Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABCA8 KIAA0822 ENSG00000141338 "ATP binding cassette subfamily A member 8" O94911 17 68867289-68955392 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 231.5;Granulosa cells: 117.3;Leydig cells: 502.6;Microglial cells: 162.1;Oligodendrocytes: 406.6;Skeletal myocytes: 216.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 31.9;ASC TERT1: 69.6;HSkMC: 53.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044914 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA044914: AB_10964859" "unprognostic (2.58e-2)" "unprognostic (2.76e-2)" "unprognostic (1.89e-1)" "unprognostic (1.65e-1)" "unprognostic (3.04e-1)" "unprognostic (6.84e-2)" "unprognostic (1.47e-2)" "unprognostic (1.33e-2)" "unprognostic (1.19e-1)" "unprognostic (5.22e-2)" "unprognostic (6.68e-2)" "unprognostic (8.76e-2)" "unprognostic (1.42e-3)" "unprognostic (3.52e-3)" "unprognostic (1.88e-1)" "unprognostic (3.29e-1)" "unprognostic (6.14e-3)" 39.1 30.5 12.6 2.8 28.1 0.0 21.3 21.0 18.3 10.0 9.6 16.4 6.2 11.9 15.6 7.6 23.7 16.9 42.1 13.6 16.1 9.5 33.7 18.2 1.1 28.2 19.8 51.5 5.7 3.8 11.1 9.0 29.0 9.5 16.9 9.2 14.8 8.6 12.3 6.2 11.8 6.6 20.7 12.4 14.3 19.5 18.4 4.5 17.0 26.7 3.0 16.3 14.6 58.1 0.0 0.0 3.9 0.0 31.9 69.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 12.0 0.0 0.0 53.5 0.0 0.8 0.0 0.4 6.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 28.1 21.0 18.3 13.6 16.1 28.2 19.8 29.0 20.7 18.4 58.1 22.6 51.3 1.1 0.7 0.0 6.0 1.8 0.0 2.8 5.0 0.7 1.0 18.8 0.0 4.3 0.0 2.1 0.2 0.3 0.0 0.0 0.0 4.8 0.4 14.0 6.8 0.0 0.0 0.5 0.0 0.1 231.5 3.1 0.3 1.3 117.3 5.7 48.1 1.1 5.0 0.6 0.0 0.0 1.9 9.4 19.4 502.6 2.6 1.8 162.1 0.0 100.3 0.0 0.5 406.6 0.0 0.0 70.3 1.9 0.4 0.0 0.1 0.0 3.3 39.5 216.6 44.5 5.1 1.7 2.5 4.7 0.3 2.1 60.9 0.0 0.4 ACHE YT ENSG00000087085 "Acetylcholinesterase (Cartwright blood group)" P22303 7 100889994-100896974 "Blood group antigen proteins, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter degradation" "Blood group antigen, Hydrolase, Serine esterase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 98.2;skeletal muscle: 163.2;tongue: 48.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 86.2;Erythroid cells: 37.7;Exocrine glandular cells: 39.7;Horizontal cells: 55.5;Paneth cells: 118.3;Proximal enterocytes: 45.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 7.9;CACO-2: 13.0;K-562: 13.9;Karpas-707: 19.7;U-2 OS: 6.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027098 Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 990000 "Cluster 80: Striated muscle - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Vesicles "HPA027098: AB_2672111" "unprognostic (2.23e-1)" "unprognostic (9.44e-2)" "unprognostic (2.71e-2)" "unprognostic (5.80e-3)" "prognostic unfavorable (5.27e-4)" "unprognostic (2.49e-1)" "unprognostic (2.54e-1)" "unprognostic (1.36e-2)" "unprognostic (2.48e-2)" "unprognostic (8.92e-2)" "unprognostic (2.65e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.88e-5)" "unprognostic (2.95e-1)" "unprognostic (2.59e-2)" "unprognostic (9.28e-2)" "unprognostic (8.38e-2)" 1.4 4.7 20.9 2.2 16.8 7.9 2.0 37.1 32.5 5.0 0.0 7.6 4.9 2.6 0.2 2.3 3.2 1.3 12.5 8.0 98.2 8.8 4.1 4.4 3.5 66.1 54.2 4.6 4.3 4.7 8.3 0.7 72.7 8.1 1.8 5.7 7.1 1.6 163.2 1.3 9.1 0.5 26.2 3.5 2.4 3.9 58.1 3.6 2.3 48.0 1.5 1.4 3.7 10.5 0.0 0.2 0.2 0.2 0.3 0.0 7.9 0.3 0.0 0.1 0.2 13.0 0.1 0.0 0.6 0.0 1.2 0.6 2.0 0.1 0.0 4.6 0.5 0.2 0.1 0.2 0.1 0.0 0.4 0.5 0.1 0.1 0.0 0.0 0.0 0.1 13.9 19.7 0.1 4.3 0.0 0.2 1.1 0.3 0.3 0.0 0.1 0.0 0.1 0.0 0.8 1.5 0.1 0.8 0.0 2.9 0.0 0.0 0.2 0.5 6.0 0.2 0.1 0.0 0.2 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.9 16.8 37.1 32.5 8.0 98.2 66.1 54.2 72.7 26.2 58.1 10.5 0.5 0.0 0.0 3.3 0.5 0.8 20.9 0.9 6.2 13.5 2.9 1.1 6.4 5.7 0.4 0.0 0.0 8.2 0.9 86.2 0.0 10.5 0.0 0.5 1.5 2.1 3.5 37.7 4.7 39.7 2.6 3.0 1.5 2.4 0.0 7.4 2.2 0.4 0.8 55.5 9.7 12.0 0.0 0.3 6.6 0.4 0.6 1.7 1.8 1.0 4.6 11.4 0.0 8.5 0.8 20.1 118.3 0.7 1.8 20.4 45.6 1.1 0.1 6.8 0.0 13.5 4.9 4.1 8.0 1.7 1.0 7.1 0.6 1.4 4.6 15.2 ADAM12 "MCMPMltna, MLTN" ENSG00000148848 "ADAM metallopeptidase domain 12" O43184 10 126012381-126388455 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "placenta: 166.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 102.2;Extravillous trophoblasts: 400.8;Oligodendrocyte precursor cells: 99.0;Syncytiotrophoblasts: 129.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "MAIT T-cell: 6.1" "Lineage enriched" "Detected in single" 62 "T-cells: 6.1" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 154.2;hTEC/SVTERT24-B: 94.3;U-2197: 93.2;U-251 MG: 86.2;U-87 MG: 70.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA030866, HPA030867, HPA030868" Enhanced Supported "Plasma membrane" "Secreted in female reproductive system" NA NA 14000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" "HPA030866: AB_2673636, HPA030867: AB_10602428, HPA030868: AB_2673638" "unprognostic (3.35e-1)" "unprognostic (1.05e-3)" "unprognostic (3.52e-2)" "unprognostic (2.47e-2)" "unprognostic (3.34e-2)" "unprognostic (2.16e-1)" "unprognostic (2.91e-6)" "unprognostic (2.17e-2)" "unprognostic (4.85e-2)" "unprognostic (1.30e-2)" "unprognostic (2.53e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.39e-14)" "unprognostic (3.11e-3)" "unprognostic (9.06e-3)" "unprognostic (4.70e-3)" "unprognostic (3.47e-3)" 11.4 0.1 2.0 6.0 4.0 0.1 4.6 1.6 2.1 18.2 3.5 0.4 0.2 6.3 0.0 0.4 0.2 11.8 0.7 1.0 2.5 1.0 0.2 1.3 3.2 6.0 2.7 8.8 0.5 0.1 1.1 166.5 3.1 0.3 0.6 0.3 1.1 0.0 0.1 0.4 0.5 4.3 1.8 1.6 0.5 0.9 10.4 1.8 0.3 0.0 3.5 11.6 0.5 3.0 16.8 2.5 6.5 0.1 18.7 38.3 0.0 42.7 3.5 14.2 35.5 0.0 0.0 0.0 0.0 154.2 30.0 0.0 0.2 1.4 15.5 1.9 0.6 0.2 25.1 0.0 2.9 0.0 33.2 47.0 0.0 94.3 2.9 27.1 0.0 0.0 0.0 0.2 11.8 0.0 0.0 0.0 0.1 0.0 2.8 0.0 4.8 4.4 0.4 44.1 0.5 28.4 5.0 0.0 0.7 2.5 0.1 0.1 0.0 50.9 16.9 93.2 86.2 0.0 0.5 0.0 70.7 0.1 32.3 0.0 0.0 0.0 0.3 0.0 6.1 0.0 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 2.0 4.0 1.6 2.1 1.0 2.5 6.0 2.7 3.1 1.8 10.4 3.0 0.5 0.0 1.9 22.5 0.3 1.5 0.4 3.0 0.0 2.1 1.7 3.6 2.3 0.0 0.5 0.0 102.2 14.0 0.5 0.7 0.0 8.0 10.9 10.7 16.6 1.6 0.0 0.0 7.4 1.1 400.8 34.5 0.5 1.8 49.5 7.8 2.5 0.2 15.5 6.7 19.0 1.0 4.1 0.6 3.1 1.7 16.8 0.8 1.8 14.0 9.0 3.3 1.0 99.0 52.2 2.2 0.1 0.7 0.3 1.0 0.7 0.4 6.5 30.5 0.0 5.1 13.4 6.0 5.0 0.0 0.6 129.2 4.7 28.1 0.9 0.5 ADGRA2 "DKFZp434C211, DKFZp434J0911, FLJ14390, GPR124, KIAA1531, TEM5" ENSG00000020181 "Adhesion G protein-coupled receptor A2" Q96PE1 8 37784191-37844896 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Wnt signaling pathway" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 30.6;Endometrial stromal cells: 49.4;Fibroblasts: 36.4;Hepatic stellate cells: 31.4;Leydig cells: 56.5;Microglial cells: 24.4;Muller glia cells: 25.0;Peritubular cells: 41.8;Sertoli cells: 46.0;Smooth muscle cells: 36.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 83.6;ASC TERT1: 64.8;BJ hTERT+: 75.2;fHDF/TERT166: 77.6;HSkMC: 39.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012393 Uncertain NA NA 270000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA012393: AB_1849256" "unprognostic (1.63e-1)" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (1.21e-1)" "unprognostic (2.00e-1)" "unprognostic (6.34e-2)" "unprognostic (1.38e-1)" "unprognostic (3.75e-2)" "unprognostic (1.15e-2)" "unprognostic (1.20e-2)" "unprognostic (3.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.18e-7)" "unprognostic (2.65e-2)" "unprognostic (4.90e-2)" "unprognostic (6.12e-2)" "unprognostic (4.60e-3)" 29.1 4.8 10.0 12.2 8.6 2.0 26.4 8.7 10.1 59.8 5.9 24.1 7.7 45.1 18.2 24.8 43.8 26.2 17.6 9.8 6.5 9.6 4.3 16.2 7.7 7.7 8.3 35.9 5.5 2.2 10.0 48.7 7.8 44.4 8.2 6.7 9.0 54.9 6.6 13.1 12.8 27.8 7.0 11.9 12.3 3.5 11.2 5.2 11.3 8.3 5.6 39.6 32.0 6.6 0.2 2.3 0.3 4.7 83.6 64.8 0.6 38.5 75.2 4.6 12.4 0.5 0.2 0.0 6.9 77.6 3.1 0.9 3.5 0.2 1.5 1.6 1.8 0.2 2.2 0.2 38.1 0.0 0.0 39.4 0.4 3.4 0.8 3.3 22.3 3.0 0.2 0.7 1.2 1.2 0.1 8.0 3.5 0.0 0.6 6.5 4.2 0.4 0.0 0.1 0.3 18.1 1.0 0.2 5.7 17.7 0.2 16.9 18.2 7.6 9.6 11.2 3.5 6.2 0.5 0.1 1.0 20.3 8.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 8.6 8.7 10.1 9.8 6.5 7.7 8.3 7.8 7.0 11.2 6.6 30.6 0.0 0.0 1.0 0.2 0.0 0.1 0.0 0.0 1.0 1.0 1.1 1.3 0.0 0.0 0.0 0.0 1.1 0.2 0.0 1.9 0.1 0.2 1.5 49.4 17.8 0.0 0.0 7.8 1.6 0.6 36.4 0.0 2.2 0.0 0.1 31.4 0.1 2.1 0.0 7.8 0.2 0.0 1.6 0.0 3.1 56.5 1.5 0.0 24.4 1.0 25.0 1.0 3.0 0.8 0.3 0.1 41.8 0.1 0.3 0.0 0.0 0.0 0.7 46.0 5.5 36.0 0.3 0.8 0.5 0.0 2.3 0.4 2.6 0.3 0.2 AFAP1 "AFAP, AFAP-110" ENSG00000196526 "Actin filament associated protein 1" Q8N556 4 7758714-7939926 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Early spermatids: 170.5;Extravillous trophoblasts: 116.3;Inhibitory neurons: 117.2;Late spermatids: 373.8;Oligodendrocyte precursor cells: 125.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.9" "Group enriched" "Detected in many" 5 "granulocytes: 2.9;T-cells: 1.2" "Cell line enhanced" "Detected in many" "TIME: 126.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015642, CAB024712" Enhanced Supported "Actin filaments,Focal adhesion sites,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Actin filaments, Cytosol" "Focal adhesion sites" "CAB024712: , HPA015642: AB_1844632" "unprognostic (1.12e-1)" "unprognostic (2.78e-2)" "unprognostic (3.97e-1)" "unprognostic (7.29e-2)" "unprognostic (2.02e-1)" "unprognostic (1.93e-1)" "unprognostic (3.30e-1)" "prognostic unfavorable (2.84e-4)" "unprognostic (2.00e-1)" "unprognostic (3.39e-2)" "unprognostic (3.40e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (8.18e-4)" "unprognostic (1.40e-2)" "unprognostic (1.56e-1)" "unprognostic (1.85e-1)" "unprognostic (2.44e-2)" 12.6 3.1 7.0 8.7 5.8 0.7 9.7 4.5 6.9 8.7 2.9 17.6 5.6 15.4 2.0 11.0 8.5 9.4 10.8 5.8 4.5 4.9 1.2 8.5 4.4 3.7 2.7 7.1 3.8 14.7 7.9 12.6 2.8 7.7 9.8 3.4 8.6 10.2 3.5 5.3 7.7 15.4 3.4 4.0 6.7 22.0 3.5 3.1 7.4 2.4 4.8 14.2 8.3 3.5 31.9 23.2 16.2 12.9 15.4 27.8 21.3 46.4 68.1 43.6 40.0 7.4 7.2 0.1 15.2 75.5 72.3 15.1 8.6 18.7 28.6 0.9 5.7 0.0 33.2 4.5 43.0 0.0 0.4 17.2 13.8 54.4 35.5 72.2 53.0 4.8 0.7 6.8 23.0 10.3 0.6 0.0 7.0 13.2 44.3 0.0 12.1 1.5 4.7 4.1 31.8 53.0 15.9 10.9 12.4 21.4 4.1 0.3 126.7 53.0 11.8 69.6 23.0 0.0 0.2 0.0 18.9 0.1 61.9 0.0 0.4 2.9 0.4 0.1 0.5 0.0 0.6 0.6 0.0 0.0 1.2 0.5 1.0 0.0 0.0 0.0 0.5 0.7 7.0 5.8 4.5 6.9 5.8 4.5 3.7 2.7 2.8 3.4 3.5 3.5 22.5 6.4 2.0 4.6 0.2 2.9 9.7 16.2 7.4 1.2 10.2 8.9 5.9 10.0 12.7 11.0 4.2 5.6 2.3 14.8 0.0 19.2 170.5 7.5 17.6 20.1 14.5 0.0 24.7 7.7 116.3 21.1 11.2 8.8 0.0 4.4 14.3 0.0 8.5 0.0 117.2 20.6 0.0 0.3 3.6 373.8 11.1 6.0 1.8 30.9 0.6 10.2 0.0 125.2 5.4 29.9 8.6 12.4 0.6 13.5 6.4 4.2 6.4 0.7 6.6 8.0 13.4 12.5 10.0 6.2 4.3 8.8 7.3 2.6 13.9 9.9 AGPAT4 "dJ473J16.2, LPAAT-delta" ENSG00000026652 "1-acylglycerol-3-phosphate O-acyltransferase 4" Q9NRZ5 6 161129967-161274061 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 51.3" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 407.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 25.5;HEL: 19.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053287, HPA060525" Approved Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "Nucleoli, Vesicles" "HPA053287: AB_2682101, HPA060525: AB_2684306" "unprognostic (5.69e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.73e-1)" "unprognostic (3.43e-2)" "unprognostic (4.14e-2)" "unprognostic (6.67e-3)" "unprognostic (1.94e-4)" "unprognostic (1.05e-1)" "unprognostic (3.42e-2)" "unprognostic (2.77e-2)" "unprognostic (1.76e-3)" "unprognostic (1.67e-1)" "prognostic unfavorable (4.08e-4)" "unprognostic (1.82e-2)" "unprognostic (8.87e-2)" "unprognostic (3.63e-4)" "unprognostic (5.51e-2)" 4.8 2.1 14.7 1.8 30.5 5.2 4.5 24.6 22.5 7.2 5.6 6.4 1.2 7.8 2.2 3.7 6.1 4.2 2.6 14.9 22.7 6.0 0.8 6.7 0.9 47.1 26.3 7.4 2.1 0.3 11.4 8.7 34.3 3.6 2.1 2.2 2.7 2.4 1.0 2.3 2.6 4.7 25.5 4.6 2.3 2.8 28.6 1.3 4.1 1.0 1.0 3.0 5.0 51.3 0.5 1.0 25.5 5.1 4.7 9.5 1.1 0.9 0.3 1.9 3.2 1.5 4.6 0.7 1.8 4.2 11.8 0.5 4.8 4.0 1.8 2.9 8.1 19.4 4.9 0.1 3.7 0.2 2.8 11.4 1.9 5.0 2.7 9.1 6.1 3.1 9.8 8.9 2.4 0.0 1.4 2.2 6.2 0.0 9.7 0.0 1.1 0.5 5.6 0.4 14.8 5.6 4.0 2.1 1.1 9.9 1.1 1.2 6.8 2.6 3.3 1.8 4.4 0.7 1.0 0.0 9.9 1.0 1.6 0.0 1.8 0.0 3.4 1.5 1.1 0.2 1.6 2.1 1.0 0.5 0.8 1.2 0.3 2.9 1.3 0.8 1.7 1.3 14.7 30.5 24.6 22.5 14.9 22.7 47.1 26.3 34.3 25.5 28.6 51.3 12.0 3.2 5.5 7.5 4.5 3.2 5.5 9.7 6.2 2.4 3.5 2.7 5.6 5.7 6.9 5.5 0.0 20.3 31.1 6.1 0.0 5.2 52.1 23.8 12.5 13.5 1.8 31.5 87.9 8.2 12.0 17.8 4.6 5.1 11.4 20.6 10.4 0.2 18.2 0.0 95.8 0.7 10.2 7.2 16.4 72.8 5.9 17.0 3.6 23.4 9.4 4.0 9.2 56.3 407.6 5.5 18.7 8.6 15.7 1.3 0.0 0.6 21.4 1.2 19.7 5.3 6.9 4.9 2.8 1.1 2.6 22.2 14.1 3.7 1.4 3.6 ANG "RAA1, RNASE5" ENSG00000214274 Angiogenin P03950 14 20684177-20698971 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Differentiation, Stress response" "Developmental protein, DNA-binding, Endonuclease, Hydrolase, Nuclease, Protein synthesis inhibitor" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 52 "liver: 3018.1" "Cell type enriched" "Detected in many" 24 "Hepatocytes: 4816.3" "Cancer enriched" "Detected in all" 17 "liver cancer: 279.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.5;myeloid DC: 14.5" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Hep G2: 152.2;OE19: 116.1" "Low region specificity" "Detected in all" HPA055896 Approved "Nucleoli,Nucleoli rim,Mitotic chromosome,Actin filaments" "Secreted to blood" Yes No 308000000 410000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Nucleoli, Nucleoli rim, Mitotic chromosome" "Actin filaments" "HPA055896: " "unprognostic (2.50e-2)" "unprognostic (1.82e-1)" "unprognostic (9.77e-2)" "prognostic favorable (6.85e-4)" "unprognostic (5.71e-3)" "unprognostic (6.99e-2)" "prognostic favorable (7.83e-5)" "unprognostic (1.16e-1)" "unprognostic (3.20e-3)" "unprognostic (9.19e-3)" "unprognostic (1.31e-1)" "unprognostic (3.69e-1)" "unprognostic (6.65e-2)" "unprognostic (1.03e-1)" "unprognostic (3.39e-1)" "unprognostic (2.00e-1)" "unprognostic (3.09e-1)" 37.6 3.0 3.6 6.0 3.5 1.0 37.8 3.5 4.9 38.2 5.6 32.6 23.2 23.4 17.9 9.8 30.5 28.5 16.9 3.6 4.9 18.4 3018.1 18.5 3.5 4.5 4.2 58.1 30.8 5.3 5.0 3.8 4.3 32.7 45.7 2.2 52.6 13.3 6.2 27.4 27.1 10.4 4.5 7.4 58.2 10.2 3.7 1.5 8.8 10.5 4.1 24.8 31.4 4.8 3.7 9.9 2.3 0.0 23.9 27.8 0.3 4.8 8.8 1.1 4.0 5.9 5.1 0.4 1.5 12.0 8.0 3.8 2.8 3.1 1.3 18.4 3.8 0.9 5.1 152.2 5.0 4.0 0.5 22.2 2.5 1.5 5.1 11.8 5.7 4.2 0.2 27.0 3.5 0.7 0.9 1.2 0.7 116.1 10.7 0.7 3.9 11.3 2.3 2.9 0.0 0.4 4.6 1.7 6.5 5.1 4.0 0.7 6.0 1.9 2.8 1.7 0.7 5.9 4.8 0.5 3.2 2.0 5.0 0.0 24.5 0.0 0.6 2.9 0.4 5.8 1.2 1.1 14.5 4.9 0.3 0.2 0.4 0.0 0.1 2.3 0.8 7.1 3.6 3.5 3.5 4.9 3.6 4.9 4.5 4.2 4.3 4.5 3.7 4.8 9.7 28.9 17.7 0.0 9.7 27.1 43.3 39.2 14.2 0.1 33.8 24.8 0.8 194.5 24.6 11.0 0.0 1.6 0.7 32.5 11.7 40.0 1.0 6.2 9.7 11.0 71.0 27.8 0.0 31.6 5.3 48.8 56.1 24.9 0.0 10.7 62.4 4816.3 15.9 0.0 0.0 171.9 12.2 95.9 18.7 2.9 71.1 13.8 23.2 0.0 4.9 10.1 0.0 0.0 0.0 21.6 33.3 24.0 11.7 43.7 91.3 61.2 76.5 0.6 13.1 29.7 17.7 1.0 1.3 9.4 52.4 9.3 5.6 0.5 51.6 39.2 ANGPTL5 ENSG00000187151 "Angiopoietin like 5" Q86XS5 11 101890674-101916522 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "ovary: 22.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 19.4;Langerhans cells: 11.3;Leydig cells: 27.7;Melanocytes: 7.2;Peritubular cells: 15.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "ASC diff: 2.7" "Region enhanced" "Detected in some" "spinal cord: 3.3" HPA038516 Uncertain "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA038516: AB_10672749" "unprognostic (8.28e-3)" "unprognostic (3.08e-2)" "unprognostic (1.21e-1)" "unprognostic (2.62e-1)" "unprognostic (3.23e-2)" "unprognostic (2.18e-1)" "unprognostic (4.88e-2)" "unprognostic (6.74e-4)" "unprognostic (1.96e-1)" "unprognostic (1.53e-8)" "unprognostic (3.40e-2)" "unprognostic (1.95e-1)" "unprognostic (1.94e-1)" "unprognostic (3.17e-3)" 4.3 0.2 0.1 0.0 0.2 0.0 5.5 0.2 0.4 0.2 0.4 0.3 0.1 0.0 4.4 0.2 0.3 0.2 2.7 0.2 0.2 0.0 0.0 0.9 0.1 0.2 0.1 22.4 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.1 0.4 0.2 0.4 2.4 0.2 0.0 0.2 0.0 0.1 1.6 0.1 0.0 0.7 1.9 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 2.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.4 0.2 0.2 0.2 0.1 0.1 0.2 0.1 0.1 0.5 0.0 0.0 0.3 0.0 6.2 0.0 0.1 0.0 0.2 0.0 0.0 0.5 0.0 0.0 1.8 0.0 0.9 0.0 0.0 0.0 0.0 2.1 0.9 0.6 0.8 0.0 0.0 2.7 0.0 0.1 19.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 2.0 0.0 0.0 0.0 11.3 0.8 27.7 0.1 7.2 4.7 0.0 0.2 0.0 1.0 0.2 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.2 1.0 0.2 0.2 0.0 5.5 0.1 0.5 5.7 0.0 0.0 ANKDD1A FLJ25870 ENSG00000166839 "Ankyrin repeat and death domain containing 1A" Q495B1 15 64911902-64958691 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 209.6;Leydig cells: 61.8;Peritubular cells: 78.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 24.1;RT4: 17.7;U-266/84: 25.4" "Low region specificity" "Detected in some" "Region enhanced" "Detected in all" "cerebellum: 13.8" HPA040757 Approved Approved Nucleoplasm "Secreted - unknown location" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA040757: AB_10960566" "unprognostic (3.72e-4)" "unprognostic (1.86e-1)" "unprognostic (6.07e-3)" "unprognostic (3.25e-2)" "unprognostic (4.78e-1)" "unprognostic (2.49e-1)" "unprognostic (1.14e-1)" "unprognostic (1.22e-3)" "unprognostic (5.11e-3)" "unprognostic (5.57e-2)" "unprognostic (4.37e-2)" "unprognostic (1.60e-1)" "unprognostic (3.15e-7)" "unprognostic (1.06e-1)" "unprognostic (1.98e-1)" "unprognostic (8.04e-3)" "unprognostic (1.64e-2)" 3.6 9.0 5.1 2.6 4.5 2.7 1.5 2.0 5.4 2.3 0.1 1.3 1.2 2.2 1.9 3.6 4.0 2.9 2.2 3.8 2.5 0.8 0.4 2.6 4.8 4.7 2.7 3.8 4.4 4.4 1.2 1.6 2.2 2.3 0.4 2.8 2.4 2.1 1.2 3.3 1.8 1.6 2.1 10.7 1.7 3.6 3.5 0.8 2.6 0.1 1.3 3.0 2.0 2.5 1.2 3.7 1.6 1.6 2.7 2.1 6.9 1.6 4.4 1.7 2.5 2.1 1.7 1.6 1.9 3.8 1.4 1.3 3.7 0.3 1.4 0.7 1.1 1.5 4.6 1.5 2.0 1.2 2.5 1.6 0.5 1.1 0.6 0.9 1.2 1.7 0.3 24.1 0.5 3.5 0.6 2.6 2.2 0.6 1.7 0.8 1.0 12.1 0.2 17.7 3.2 4.5 1.0 1.2 1.8 1.5 1.2 1.5 1.8 3.2 3.3 2.8 1.6 6.4 25.4 1.2 3.6 3.0 1.0 0.5 0.4 0.0 1.0 0.9 0.3 0.4 0.5 1.4 0.7 0.3 0.3 0.4 0.7 3.1 0.9 0.0 2.1 0.4 5.1 4.5 2.0 5.4 3.8 2.5 4.7 2.7 2.2 2.1 3.5 2.5 8.0 0.0 1.3 209.6 1.5 5.6 4.2 1.1 4.0 11.2 0.7 1.0 1.4 1.5 1.3 0.0 12.5 3.1 3.8 0.1 0.0 0.9 1.1 1.7 9.6 12.7 1.2 0.0 37.7 2.3 5.6 6.5 0.0 3.6 5.7 1.1 5.3 0.0 5.4 3.3 24.6 0.0 2.0 6.0 25.4 4.1 61.8 7.1 10.6 19.7 1.1 28.9 5.2 30.2 10.7 2.8 0.1 78.6 6.2 2.7 0.0 0.3 0.2 8.2 13.1 11.8 7.1 2.6 1.3 0.8 3.7 2.2 3.0 3.3 0.1 5.2 ANKRD13B FLJ25555 ENSG00000198720 "Ankyrin repeat domain 13B" Q86YJ7 17 29589769-29614761 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 27.4;Endometrial stromal cells: 24.2;Excitatory neurons: 19.4;Horizontal cells: 16.8;Late spermatids: 44.7;Oligodendrocytes: 17.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 52.0;SH-SY5Y: 57.6;SK-BR-3: 48.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051886, HPA063748" Uncertain Supported Vesicles NA NA "Cluster 43: Testis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA051886: AB_2681652, HPA063748: AB_2685112" "unprognostic (1.61e-1)" "unprognostic (2.01e-1)" "unprognostic (1.27e-1)" "unprognostic (1.66e-2)" "unprognostic (1.53e-1)" "unprognostic (2.45e-1)" "unprognostic (3.10e-4)" "unprognostic (1.84e-1)" "unprognostic (1.84e-1)" "unprognostic (1.03e-2)" "prognostic favorable (7.58e-4)" "unprognostic (3.94e-2)" "prognostic unfavorable (5.92e-6)" "unprognostic (9.93e-2)" "unprognostic (1.18e-1)" "unprognostic (3.94e-2)" "unprognostic (5.36e-3)" 12.0 3.7 12.5 1.7 14.3 0.7 7.5 11.9 15.9 16.3 0.0 10.2 0.8 13.6 0.8 6.5 12.0 3.7 10.3 13.9 6.2 2.8 1.2 5.5 1.6 13.4 9.4 15.1 3.7 1.6 14.6 0.9 10.4 7.7 0.6 2.0 4.3 1.8 9.6 7.5 4.5 2.9 7.2 2.6 4.9 18.9 10.8 0.9 5.8 1.3 0.3 10.0 11.6 22.9 6.6 11.5 13.3 35.4 8.2 8.0 5.1 2.0 1.2 1.4 2.7 6.1 1.4 7.4 6.4 2.8 4.9 24.3 7.2 7.8 0.2 14.8 23.5 2.3 22.3 5.3 3.5 2.4 4.6 7.9 10.2 2.2 5.8 6.4 10.1 12.8 6.0 6.1 1.9 5.9 16.0 7.5 11.4 6.8 9.7 33.4 9.5 23.4 3.0 2.2 52.0 57.6 3.9 48.0 4.3 1.2 7.4 4.4 6.7 7.4 7.2 5.2 7.2 11.4 15.7 9.2 5.2 12.1 4.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 14.3 11.9 15.9 13.9 6.2 13.4 9.4 10.4 7.2 10.8 22.9 2.6 0.0 0.0 6.8 0.1 1.7 1.0 0.7 3.4 4.5 1.8 2.7 2.3 0.0 0.4 0.0 2.1 0.1 0.6 0.6 1.9 1.6 27.4 0.9 24.2 2.4 3.0 1.7 19.4 0.6 0.2 5.5 2.6 1.0 0.0 3.8 1.4 0.6 0.1 16.8 14.6 0.8 0.0 0.3 1.6 44.7 14.6 0.3 0.0 0.0 0.0 1.8 0.0 11.1 17.8 0.5 0.0 7.5 0.5 3.2 0.1 0.2 0.0 5.2 0.0 2.4 2.5 6.0 4.7 2.6 1.7 0.1 0.7 1.0 1.1 1.5 ANKRD35 FLJ25124 ENSG00000198483 "Ankyrin repeat domain 35" Q8N283 1 145866560-145885866 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 60.8" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 56.4;Fibroblasts: 31.2;Leydig cells: 36.4;Muller glia cells: 57.7;Peritubular cells: 50.8;Skeletal myocytes: 29.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC TERT1: 9.6;THP-1: 6.8;TIME: 8.4;U-87 MG: 8.3;U-937: 7.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035453 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Nucleoplasm "HPA035453: AB_10672864" "prognostic favorable (9.35e-4)" "prognostic favorable (2.90e-4)" "unprognostic (2.07e-1)" "unprognostic (7.39e-3)" "unprognostic (1.77e-2)" "unprognostic (1.02e-2)" "unprognostic (3.27e-1)" "unprognostic (3.58e-2)" "unprognostic (3.03e-1)" "unprognostic (1.79e-1)" "unprognostic (2.98e-1)" "unprognostic (5.86e-2)" "unprognostic (9.29e-10)" "unprognostic (8.80e-3)" "unprognostic (2.18e-1)" "unprognostic (5.92e-2)" "unprognostic (8.69e-3)" 4.0 1.3 8.2 1.1 7.9 0.3 4.6 7.6 9.7 20.6 6.4 6.0 0.5 5.8 1.4 24.7 6.6 1.3 2.9 7.5 8.6 0.8 2.5 2.3 0.4 8.7 9.5 4.4 0.7 0.0 2.0 0.1 8.5 6.6 0.8 1.3 11.4 2.7 8.2 60.8 2.5 2.1 8.4 0.5 3.9 1.6 9.0 0.5 1.7 3.8 6.7 7.3 20.6 7.6 0.1 0.0 0.0 0.0 2.2 9.6 0.2 1.4 3.6 0.4 1.2 0.4 0.0 0.0 0.3 1.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 1.1 2.9 0.1 3.3 0.4 0.3 0.0 0.1 0.4 0.0 0.0 0.0 2.2 0.0 0.0 3.9 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 8.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 8.3 7.5 0.0 0.0 2.1 0.0 0.7 0.8 0.1 0.0 0.3 1.1 0.3 0.0 0.2 0.7 0.1 0.7 0.2 0.5 0.7 0.7 8.2 7.9 7.6 9.7 7.5 8.6 8.7 9.5 8.5 8.4 9.0 7.6 1.6 0.0 0.0 6.8 0.3 4.6 16.8 10.2 0.0 1.1 6.3 13.5 1.5 2.8 9.5 1.8 0.0 0.1 2.2 0.0 0.0 0.0 3.5 56.4 10.9 1.3 0.0 2.7 5.6 0.4 0.1 31.2 0.5 17.2 19.1 0.0 2.2 13.9 11.0 0.0 2.1 0.0 14.2 1.2 4.6 5.9 36.4 1.1 5.4 1.0 1.1 57.7 5.2 3.0 0.6 0.1 0.0 50.8 0.4 5.3 0.0 0.1 9.8 2.7 0.0 29.5 6.4 0.1 1.0 10.4 12.4 0.3 5.5 1.1 0.0 13.6 ANKRD65 ENSG00000235098 "Ankyrin repeat domain 65" E5RJM6 1 1418420-1421769 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 65.0;Glandular and luminal cells: 88.4;Respiratory ciliated cells: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "myeloid DC: 3.5;plasmacytoid DC: 7.8" "Lineage enriched" "Detected in single" 23 "dendritic cells: 7.8" "Group enriched" "Detected in some" 8 "Hep G2: 35.9;RT4: 34.5;SCLC-21H: 46.3" "Not detected" "Not detected" HPA065720 Enhanced Approved Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA065720: AB_2685545" "unprognostic (2.17e-2)" "unprognostic (2.52e-2)" "unprognostic (1.21e-1)" "unprognostic (2.77e-1)" "unprognostic (1.48e-1)" "unprognostic (1.69e-2)" "unprognostic (1.59e-1)" "prognostic favorable (1.08e-5)" "unprognostic (1.64e-1)" "unprognostic (4.39e-1)" "unprognostic (1.16e-1)" "unprognostic (4.43e-2)" "unprognostic (5.14e-2)" "unprognostic (3.02e-3)" "unprognostic (1.81e-2)" "unprognostic (8.04e-2)" "unprognostic (2.76e-2)" 6.0 1.0 24.6 3.2 29.5 0.2 10.3 25.6 25.9 8.8 18.5 14.2 2.3 7.6 5.9 15.6 36.7 2.9 4.1 22.0 25.2 6.0 1.5 11.2 9.1 31.0 28.5 8.5 15.2 1.4 2.3 6.9 29.4 19.9 1.7 2.5 16.1 21.9 3.1 7.0 6.3 4.0 24.0 1.6 9.9 7.3 25.7 7.8 4.3 3.3 7.2 21.1 9.4 34.8 1.0 0.0 0.3 0.0 0.0 0.1 0.8 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.5 0.9 0.0 4.5 0.3 4.3 0.0 0.5 0.4 0.0 0.0 35.9 0.8 0.1 0.0 0.4 5.1 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.2 0.1 0.0 0.3 4.6 0.0 0.0 34.5 46.3 0.5 0.2 0.0 0.1 0.4 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 3.5 0.3 0.0 0.3 0.0 0.0 0.0 7.8 0.0 0.2 24.6 29.5 25.6 25.9 22.0 25.2 31.0 28.5 29.4 24.0 25.7 34.8 11.8 22.4 29.0 5.5 0.1 2.2 12.9 14.1 13.1 8.5 5.9 32.5 0.7 14.3 20.1 1.8 0.0 26.0 0.0 0.0 9.8 19.0 0.0 65.0 20.5 11.7 1.8 2.7 4.4 30.7 0.8 13.3 3.1 88.4 8.8 2.9 1.4 0.8 2.2 8.4 2.0 0.0 14.2 1.0 3.3 0.9 20.8 1.5 3.6 1.0 1.2 16.6 0.0 3.5 20.5 11.0 0.1 29.0 0.1 6.3 0.0 0.5 51.8 3.1 0.0 25.7 3.6 0.3 0.3 10.7 3.1 16.8 1.1 0.7 0.0 10.8 APCDD1L FLJ90166 ENSG00000198768 "APC down-regulated 1 like" Q8NCL9 20 58459101-58515399 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "salivary gland: 19.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 9.1;Breast myoepithelial cells: 7.7;Fibroblasts: 3.6;Oligodendrocyte precursor cells: 6.0;Skeletal myocytes: 8.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 94.5;hTEC/SVTERT24-B: 32.7;HUVEC TERT2: 33.6;TIME: 56.1;U-87 MG: 36.5" "Not detected" "Not detected" HPA067015 Uncertain Uncertain Mitochondria No No "Cluster 24: Salivary gland - Salivary secretion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA067015: AB_2685764" "unprognostic (2.61e-1)" "unprognostic (8.26e-3)" "unprognostic (4.63e-3)" "unprognostic (1.35e-5)" "unprognostic (4.09e-3)" "unprognostic (9.73e-3)" "unprognostic (1.31e-3)" "unprognostic (1.06e-4)" "unprognostic (7.63e-4)" "unprognostic (2.14e-2)" "unprognostic (7.62e-3)" "unprognostic (2.16e-1)" "unprognostic (6.55e-13)" "unprognostic (5.01e-3)" "unprognostic (3.21e-1)" "unprognostic (2.24e-2)" "unprognostic (1.81e-3)" 0.4 0.4 0.2 0.2 0.0 0.0 4.8 0.5 0.1 1.7 0.0 1.0 0.1 1.8 0.0 0.5 0.0 0.7 1.4 0.1 0.0 2.9 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.4 0.1 0.0 0.5 0.6 0.0 19.2 1.3 0.6 0.8 0.4 0.6 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 4.4 0.6 0.0 0.0 0.0 0.0 0.0 0.4 3.1 0.0 16.8 0.1 1.9 1.4 0.0 5.6 0.0 0.0 94.5 0.5 1.1 0.0 3.3 3.3 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 2.6 0.0 32.7 0.5 6.8 33.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 56.1 12.6 0.9 0.0 16.5 0.0 0.0 0.0 36.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.0 0.1 0.0 0.3 0.4 0.0 0.0 9.1 7.7 0.9 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.0 0.7 0.0 0.0 3.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 6.0 0.5 0.8 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 8.4 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 APOE AD2 ENSG00000130203 "Apolipoprotein E" P02649 19 44905791-44909393 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Hyperlipidemia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adrenal gland: 3453.9;liver: 6592.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 9363.4;Hofbauer cells: 6072.6;Muller glia cells: 9454.8;Peritubular cells: 4958.2;Proximal tubular cells: 8155.9;Theca cells: 7201.0" "Cancer enhanced" "Detected in all" "liver cancer: 3183.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1867.0;CACO-2: 466.1;Hep G2: 935.3;HSkMC: 1374.2;SK-MEL-30: 1956.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008363, HPA065539, HPA068768, CAB069921" Enhanced Approved Vesicles "Secreted to blood" NA NA 51800000000 29000000000 "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB008363: AB_590560, CAB069921: AB_920623, HPA065539: AB_2685509, HPA068768: AB_2686029" "unprognostic (8.98e-2)" "unprognostic (2.32e-2)" "unprognostic (2.49e-2)" "unprognostic (5.28e-2)" "unprognostic (3.77e-2)" "unprognostic (7.25e-2)" "unprognostic (5.22e-3)" "unprognostic (6.13e-2)" "unprognostic (5.06e-2)" "unprognostic (4.13e-1)" "unprognostic (5.78e-2)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (7.76e-2)" "unprognostic (1.64e-1)" "unprognostic (1.12e-3)" "unprognostic (4.13e-2)" 522.1 3453.9 813.4 92.8 1164.2 66.5 325.1 775.0 943.2 271.2 329.2 130.9 40.3 81.5 20.0 37.2 72.2 100.2 176.3 606.1 841.6 1066.0 6592.5 258.8 352.2 1016.0 1037.0 508.2 41.9 34.5 110.9 102.2 1106.9 45.4 22.9 87.6 80.5 10.8 31.1 381.2 165.9 12.6 823.2 620.3 83.3 140.5 962.6 57.8 146.4 10.4 46.1 93.4 135.5 964.4 3.2 5.2 9.5 2.6 1867.0 76.3 69.4 1.5 4.3 8.4 1.4 466.1 2.8 2.0 9.9 0.3 9.1 6.4 12.6 2.1 0.7 1.7 4.0 3.3 1.7 935.3 192.4 6.8 2.3 1374.2 2.5 14.8 1.3 15.6 1.0 0.7 124.9 2.8 1.2 3.3 1.9 2.5 243.2 3.0 1.3 2.6 8.0 1.8 2.8 0.9 5.6 2.4 4.5 1.4 1956.0 131.6 165.3 52.8 3.3 13.2 3.1 1.4 1.6 5.9 8.6 3.8 5.9 4.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 813.4 1164.2 775.0 943.2 606.1 841.6 1016.0 1037.0 1106.9 823.2 962.6 964.4 136.7 0.0 8.2 444.0 66.1 935.2 12.3 18.3 67.7 81.7 86.7 565.8 2.2 450.4 5.2 228.1 41.7 46.3 6.0 2.2 682.9 1.8 73.6 33.8 936.6 140.2 0.0 331.6 1.1 0.7 43.8 860.7 3.6 22.9 174.4 103.6 208.9 9363.4 6072.6 38.7 2.1 0.6 4.1 718.0 292.6 355.3 2629.4 940.6 2481.3 60.9 70.3 9454.8 0.0 12.1 2.2 0.6 0.3 4958.2 7.2 15.0 0.2 8155.9 1.0 311.4 223.5 2958.4 345.5 14.8 12.8 15.1 1684.9 74.3 60.6 7201.0 1.7 4.7 ARSI "FLJ16069, SPG66" ENSG00000183876 "Arylsulfatase family member I" Q5FYB1 5 150296343-150339307 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 12.1;Fibroblasts: 10.8;Melanocytes: 21.4;Smooth muscle cells: 6.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 10.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 15.7;HaCaT: 31.4;Hep G2: 19.9;hTEC/SVTERT24-B: 30.9;U-87 MG: 39.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "HPA038386, HPA038398" Uncertain Approved "Golgi apparatus" "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA038386: AB_10669781, HPA038398: AB_2675995" "unprognostic (6.08e-2)" "unprognostic (1.70e-2)" "unprognostic (9.41e-3)" "unprognostic (4.77e-3)" "unprognostic (1.54e-3)" "unprognostic (2.83e-3)" "unprognostic (2.76e-1)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.06e-1)" "unprognostic (5.81e-3)" "unprognostic (4.85e-2)" "unprognostic (1.26e-1)" "unprognostic (3.39e-7)" "unprognostic (7.18e-2)" "unprognostic (1.29e-1)" "unprognostic (3.64e-3)" "prognostic unfavorable (1.19e-4)" 1.2 0.3 1.6 2.3 2.6 0.6 0.4 2.5 2.1 2.7 0.7 1.6 0.6 3.1 0.6 1.8 2.1 1.1 1.3 1.4 1.8 0.7 0.4 4.5 0.3 3.6 2.4 0.4 0.4 0.6 1.0 2.8 3.9 1.7 0.4 0.4 0.5 0.8 0.8 4.8 0.7 2.8 2.6 0.8 0.8 0.4 2.8 0.3 0.2 0.5 0.4 3.8 2.7 5.5 1.0 3.8 1.1 0.0 0.0 0.8 0.0 8.1 12.1 15.7 11.5 1.1 1.8 0.0 3.1 11.5 1.3 31.4 0.2 5.3 5.6 0.0 0.1 0.0 0.4 19.9 1.5 0.0 0.0 0.8 3.4 30.9 0.9 10.7 0.2 0.0 0.0 0.2 2.5 0.0 0.0 0.0 1.7 0.0 0.8 0.0 0.0 0.1 0.4 0.0 0.2 0.0 6.7 0.9 1.3 11.2 0.0 0.0 0.0 0.3 10.2 0.3 0.0 0.0 0.0 0.0 39.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.6 2.5 2.1 1.4 1.8 3.6 2.4 3.9 2.6 2.8 5.5 0.1 0.0 0.0 0.3 0.0 12.1 0.0 2.4 0.0 0.1 0.1 0.4 1.0 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.2 0.0 0.0 0.1 0.0 1.1 10.8 0.0 0.0 4.5 0.0 0.0 0.0 1.1 0.0 0.0 0.0 4.1 0.0 0.8 0.2 0.6 0.0 21.4 0.0 0.0 3.9 0.0 0.0 2.5 0.4 0.0 0.4 0.0 0.0 0.0 1.2 0.0 0.3 0.0 1.8 6.6 0.1 0.9 0.9 4.7 1.4 1.1 0.0 0.0 0.0 AZIN2 "ADC, KIAA1945, ODC-p, ODC1L, ODCp" ENSG00000142920 "Antizyme inhibitor 2" Q96A70 1 33081104-33123492 "Metabolic proteins, Predicted intracellular proteins" "Polyamine biosynthesis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 32.1" "Group enriched" "Detected in many" 6 "Early spermatids: 233.2;Late spermatids: 855.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 6.4;plasmacytoid DC: 18.9" "Group enriched" "Detected in many" 8 "dendritic cells: 18.9;granulocytes: 6.4" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 11.0;SK-MEL-30: 14.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028527 Approved Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 78: Testis - Spermatogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA028527: AB_10602077" "unprognostic (5.33e-2)" "unprognostic (1.60e-1)" "unprognostic (2.16e-3)" "unprognostic (7.50e-2)" "unprognostic (8.28e-2)" "unprognostic (4.56e-2)" "unprognostic (1.15e-4)" "unprognostic (9.19e-3)" "unprognostic (3.89e-2)" "unprognostic (1.54e-2)" "unprognostic (1.06e-3)" "unprognostic (2.16e-1)" "unprognostic (3.18e-1)" "unprognostic (6.91e-2)" "unprognostic (2.91e-1)" "unprognostic (9.45e-2)" "unprognostic (2.41e-1)" 1.4 3.8 7.1 0.8 8.4 0.1 2.1 8.4 9.4 3.8 5.4 3.5 0.4 2.4 1.1 0.9 4.3 1.9 3.6 7.5 7.3 2.7 0.7 1.3 1.0 8.3 7.8 6.3 1.6 3.3 3.5 0.5 8.0 2.2 1.1 3.0 2.2 1.7 1.0 1.4 1.3 1.4 9.8 1.1 1.0 32.1 7.6 1.1 2.5 1.9 1.2 1.4 2.1 12.9 0.5 0.0 1.8 0.3 0.9 3.0 0.2 0.6 1.8 1.3 1.1 0.0 1.5 0.0 0.8 0.5 1.0 0.2 0.9 0.2 0.7 0.0 0.0 0.4 0.0 0.0 3.6 0.0 1.6 3.5 2.0 1.5 1.3 11.0 0.3 0.3 0.0 0.1 1.4 0.0 0.2 0.4 0.8 0.3 0.0 0.2 2.1 0.1 2.1 0.2 0.2 1.3 0.5 0.0 14.0 1.2 0.0 0.3 0.1 0.0 0.8 1.1 0.2 0.8 0.0 0.0 3.2 0.0 0.6 6.4 0.0 0.0 1.4 0.0 1.3 0.1 1.6 1.4 0.0 0.0 1.6 1.6 0.1 0.0 0.0 18.9 0.0 0.8 7.1 8.4 8.4 9.4 7.5 7.3 8.3 7.8 8.0 9.8 7.6 12.9 2.6 0.0 3.0 24.2 2.3 0.0 2.9 0.0 2.8 6.5 3.8 5.2 1.0 0.0 0.6 1.8 18.8 0.5 11.4 10.8 0.0 1.7 233.2 1.7 1.5 2.6 1.2 0.0 45.4 1.4 0.4 4.8 7.7 0.3 0.0 2.0 1.8 0.1 1.2 6.7 27.3 1.4 0.0 0.6 0.0 855.9 6.2 2.8 0.0 44.0 1.7 12.2 0.0 23.6 86.0 1.5 5.2 7.5 1.0 1.5 0.8 3.1 2.2 7.9 6.6 2.9 2.7 22.2 5.8 0.5 0.0 0.3 3.3 2.1 3.3 1.0 BMP1 "BMP-1, PCOLC" ENSG00000168487 "Bone morphogenetic protein 1" P13497 8 22165140-22212326 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor, Hydrolase, Metalloprotease, Protease" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 69.3;Endometrial stromal cells: 52.8;Smooth muscle cells: 43.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014572 Enhanced "Secreted to extracellular matrix" NA NA 9200000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA014572: AB_1845390" "unprognostic (1.24e-1)" "unprognostic (8.01e-2)" "unprognostic (3.75e-2)" "unprognostic (5.89e-2)" "unprognostic (1.34e-2)" "unprognostic (6.76e-2)" "unprognostic (9.53e-2)" "unprognostic (2.64e-3)" "unprognostic (1.66e-1)" "unprognostic (9.75e-3)" "unprognostic (7.05e-3)" "unprognostic (3.14e-2)" "prognostic unfavorable (3.37e-9)" "unprognostic (2.11e-2)" "unprognostic (6.57e-2)" "unprognostic (1.50e-3)" "unprognostic (3.34e-2)" 11.7 17.4 3.8 6.3 4.6 1.4 9.0 4.7 4.4 15.6 4.9 8.1 4.8 12.7 3.9 7.0 11.8 9.8 5.9 4.3 3.9 7.7 14.7 8.3 1.7 5.0 4.1 5.9 4.4 3.4 3.4 27.3 4.1 9.6 5.3 0.6 3.7 6.1 3.4 6.2 5.9 14.4 4.3 5.0 4.3 2.4 4.2 1.5 10.0 3.1 1.8 10.4 10.3 4.4 15.2 20.4 7.4 30.2 47.8 41.8 23.2 54.1 50.1 33.8 27.6 5.1 27.4 3.7 32.0 56.9 18.9 51.2 5.1 27.8 6.5 3.6 6.9 6.7 24.5 7.9 31.7 2.9 14.3 49.8 26.5 25.2 11.4 78.3 31.4 5.2 7.1 10.6 19.6 4.6 1.4 3.0 4.7 17.0 8.3 6.4 8.2 15.2 26.7 4.1 2.8 10.6 52.5 3.1 13.4 20.4 5.0 8.3 41.4 17.0 18.4 32.3 23.9 4.0 2.2 0.6 23.8 10.1 28.0 0.0 0.4 0.0 0.6 0.1 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.2 0.0 0.1 3.8 4.6 4.7 4.4 4.3 3.9 5.0 4.1 4.1 4.3 4.2 4.4 12.5 6.4 69.3 5.5 0.8 6.2 5.2 22.6 4.0 2.6 5.0 6.1 4.9 2.8 6.7 5.5 0.0 3.3 3.2 31.9 0.0 25.1 0.7 3.1 52.8 14.1 3.0 0.8 3.5 8.2 9.5 28.7 1.1 5.7 15.2 13.9 14.6 20.1 4.3 1.7 2.7 6.2 0.0 3.4 6.1 1.1 10.2 5.4 10.6 4.7 1.0 2.2 3.1 6.6 6.7 15.3 18.6 10.9 2.8 4.7 13.2 4.1 2.2 1.1 26.3 6.4 43.7 1.5 4.0 6.5 5.3 24.4 3.3 34.2 10.7 8.0 BMP4 BMP2B ENSG00000125378 "Bone morphogenetic protein 4" P12644 14 53949736-53958761 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 47.3;Fibroblasts: 65.2;Hepatic stellate cells: 52.8;Pancreatic endocrine cells: 40.1;Skeletal myocytes: 51.0;Syncytiotrophoblasts: 34.8" "Cancer enhanced" "Detected in all" "colorectal cancer: 28.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 1.9" "Group enriched" "Detected in many" 12 "monocytes: 1.9;T-cells: 1.3" "Cell line enhanced" "Detected in many" "CACO-2: 120.1;CAPAN-2: 298.6;Hep G2: 326.0;OE19: 219.1;SuSa: 168.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006863, HPA066235" Uncertain "Secreted to blood" NA NA 162000000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "CAB006863: , HPA066235: AB_2685641" "unprognostic (1.30e-1)" "unprognostic (3.27e-2)" "unprognostic (1.29e-1)" "unprognostic (5.20e-3)" "unprognostic (3.39e-2)" "unprognostic (3.32e-1)" "unprognostic (2.78e-2)" "unprognostic (3.11e-1)" "unprognostic (3.45e-3)" "unprognostic (7.67e-2)" "unprognostic (2.45e-3)" "unprognostic (7.06e-2)" "unprognostic (1.58e-2)" "unprognostic (2.93e-3)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" "unprognostic (1.24e-1)" 14.0 13.4 3.0 6.1 3.2 0.1 13.4 7.0 4.5 21.0 32.4 25.6 17.0 8.9 2.5 12.9 9.7 14.4 16.3 3.1 2.8 9.0 4.2 13.4 9.6 3.6 3.3 23.8 3.4 2.7 4.7 44.4 3.9 21.9 28.9 2.7 10.5 18.7 11.5 15.3 19.2 9.0 3.2 6.5 23.8 2.0 3.9 3.4 8.5 17.7 4.2 27.4 23.5 4.7 15.6 40.0 2.1 1.8 0.5 0.4 0.6 7.9 34.0 20.1 15.5 120.1 298.6 0.0 97.2 0.1 2.2 73.2 8.6 1.0 10.7 4.1 5.9 0.2 8.3 326.0 19.4 0.0 1.0 0.0 2.8 9.5 0.5 61.1 59.3 6.8 0.0 0.3 9.7 6.9 5.3 0.3 13.9 219.1 3.4 0.2 10.5 0.3 28.5 1.3 0.1 0.3 0.0 1.1 0.9 168.2 38.8 1.5 2.9 0.6 87.1 0.3 1.4 0.2 0.1 1.0 0.1 0.1 4.3 0.0 0.6 0.0 0.1 1.1 0.0 0.0 0.9 0.2 0.1 0.0 1.3 0.4 0.0 0.0 1.9 0.0 0.0 0.3 3.0 3.2 7.0 4.5 3.1 2.8 3.6 3.3 3.9 3.2 3.9 4.7 7.6 9.6 7.3 1.0 0.6 27.5 4.0 16.1 47.3 0.3 8.0 10.4 5.7 14.3 6.0 5.5 0.0 29.3 0.1 1.0 3.9 5.5 2.5 0.7 18.9 18.2 0.0 2.7 1.3 0.2 18.9 65.2 0.5 0.7 1.3 0.9 52.8 2.0 3.7 0.0 0.4 5.3 2.0 0.6 5.9 1.0 10.5 0.4 3.6 1.9 0.0 0.5 0.0 1.0 0.3 40.1 4.0 1.5 0.1 2.3 0.6 2.4 5.8 1.5 0.0 51.0 10.5 1.4 2.2 7.5 17.5 34.8 1.0 1.4 4.0 1.4 BNC1 "BNC, HsT19447" ENSG00000169594 "Basonuclin 1" Q01954 15 83255903-83284714 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" DNA-binding "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 15.0;esophagus: 12.5;testis: 30.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 88.6;Early spermatids: 45.5;Late spermatids: 103.4;Suprabasal keratinocytes: 58.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 25.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 51.1;HBEC3-KT: 116.6;hTCEpi: 128.1;hTERT-HME1: 123.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA063183, HPA066947, HPA077428" Enhanced Nucleoplasm NA NA "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA063183: AB_2684957, HPA066947: AB_2685752, HPA077428: AB_2732345" "unprognostic (1.86e-3)" "unprognostic (1.08e-1)" "unprognostic (7.89e-3)" "unprognostic (5.55e-2)" "unprognostic (4.06e-2)" "unprognostic (2.47e-2)" "unprognostic (2.45e-2)" "unprognostic (7.91e-2)" "unprognostic (8.89e-4)" "unprognostic (6.94e-2)" "unprognostic (4.13e-1)" "unprognostic (3.85e-3)" "unprognostic (8.46e-3)" "unprognostic (2.20e-1)" "unprognostic (2.95e-3)" "unprognostic (1.01e-2)" 15.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 3.1 0.0 0.1 0.0 0.0 8.1 12.5 0.9 0.1 1.4 0.2 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.7 0.0 1.0 0.0 1.8 0.0 0.2 0.0 0.1 2.0 0.2 0.0 9.3 0.0 0.0 0.0 0.0 0.1 30.8 0.3 4.2 0.1 0.3 2.1 0.3 6.5 0.4 25.9 0.1 0.0 0.0 4.2 6.4 0.0 2.0 0.3 21.9 30.3 0.0 0.5 0.0 1.0 13.8 0.0 51.1 2.7 116.6 39.3 0.0 0.2 0.0 0.0 0.0 32.6 0.0 0.0 5.6 128.1 19.6 123.8 4.5 21.7 0.0 0.0 0.0 16.6 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 4.6 0.0 0.0 0.0 11.6 0.0 0.0 14.2 0.0 0.0 40.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.1 0.0 0.0 0.0 0.0 88.6 14.8 15.5 14.8 0.0 0.0 0.1 0.4 1.5 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 45.5 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 6.9 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 5.5 103.4 0.6 0.1 8.8 1.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.7 0.0 1.2 0.0 0.1 1.7 0.0 0.0 2.7 0.6 22.2 6.5 21.7 58.4 0.0 0.0 0.0 0.0 4.8 BRSK1 KIAA1811 ENSG00000160469 "BR serine/threonine kinase 1" Q8TDC3 19 55282072-55312562 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 141.8;pituitary gland: 53.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 34.8;Excitatory neurons: 30.1;Horizontal cells: 38.7;Inhibitory neurons: 27.6;Oligodendrocyte precursor cells: 17.1;Oligodendrocytes: 29.4;Proximal enterocytes: 23.6" "Cancer enhanced" "Detected in all" "glioma: 12.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 56.4;SH-SY5Y: 51.8;WM-115: 46.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021212, HPA061719" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 65: Brain - Ion transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Cell Junctions" "HPA021212: AB_1845455, HPA061719: AB_2684593" "unprognostic (1.42e-3)" "unprognostic (2.92e-2)" "unprognostic (1.20e-1)" "unprognostic (6.69e-3)" "unprognostic (2.71e-1)" "unprognostic (4.21e-2)" "unprognostic (3.06e-6)" "unprognostic (4.24e-1)" "unprognostic (2.06e-2)" "unprognostic (3.04e-1)" "prognostic favorable (1.02e-4)" "unprognostic (3.00e-1)" "prognostic unfavorable (7.98e-6)" "unprognostic (1.16e-1)" "unprognostic (6.61e-3)" "unprognostic (1.34e-1)" "unprognostic (2.09e-1)" 1.5 12.0 75.0 3.7 90.1 0.5 2.6 47.5 141.8 5.9 0.0 11.8 3.8 8.3 4.0 3.2 5.4 4.4 12.8 103.2 66.1 2.4 0.7 1.9 2.7 70.4 54.8 5.5 2.8 16.9 53.0 1.1 66.8 8.3 1.6 20.4 2.3 5.0 0.7 1.5 4.7 5.6 32.9 1.8 4.9 11.4 74.1 2.3 3.1 1.4 1.4 6.3 4.6 105.5 0.8 2.8 33.2 17.6 0.1 1.4 0.3 5.9 7.7 7.1 10.3 13.1 5.9 7.0 3.7 6.2 6.6 0.3 7.0 0.3 6.6 33.3 28.0 4.6 4.0 1.4 7.0 1.5 12.8 4.6 0.6 7.3 0.0 27.4 0.3 17.9 6.6 40.8 6.5 1.9 9.0 1.7 24.9 0.7 2.3 20.4 8.5 1.1 0.5 0.0 56.4 51.8 0.1 1.0 12.8 9.2 2.9 3.8 0.0 13.7 15.2 7.7 10.8 37.9 28.0 16.6 13.8 3.1 46.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 75.0 90.1 47.5 141.8 103.2 66.1 70.4 54.8 66.8 32.9 74.1 105.5 0.3 0.0 1.3 9.4 5.2 0.1 1.0 0.1 1.2 34.8 0.9 2.2 1.2 0.0 0.6 1.8 2.1 0.0 1.2 10.4 0.0 0.4 1.2 0.3 3.8 0.9 3.5 0.0 30.1 0.0 0.0 1.2 0.5 0.3 0.0 2.3 0.0 0.0 1.6 38.7 27.6 1.6 0.0 6.6 0.4 0.3 0.6 1.0 0.0 1.0 2.3 4.1 3.1 17.1 29.4 0.5 0.1 4.9 9.8 1.0 23.6 0.9 0.2 10.1 0.0 0.6 2.1 3.9 7.0 0.0 0.0 0.0 1.1 2.8 1.9 0.2 C11orf80 "FLJ22531, TOPOVIBL" ENSG00000173715 "Chromosome 11 open reading frame 80" Q8N6T0 11 66744451-66843516 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Meiosis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 41.0" "Cell type enhanced" "Detected in many" "Early spermatids: 66.0;Excitatory neurons: 101.2;Inhibitory neurons: 73.8;Late spermatids: 125.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038932, HPA038933" Approved Approved Centrosome NA NA "Cluster 37: B-cells - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 21: OE19 - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Centrosome "HPA038932: AB_2676275, HPA038933: AB_10671867" "unprognostic (2.81e-1)" "unprognostic (4.39e-2)" "unprognostic (1.71e-2)" "unprognostic (6.69e-2)" "unprognostic (3.30e-1)" "unprognostic (2.09e-1)" "unprognostic (5.54e-3)" "unprognostic (4.16e-1)" "unprognostic (4.26e-2)" "unprognostic (6.59e-2)" "unprognostic (4.04e-2)" "unprognostic (2.53e-2)" "unprognostic (6.31e-2)" "unprognostic (1.23e-1)" "unprognostic (4.98e-1)" "unprognostic (3.72e-2)" "unprognostic (1.26e-1)" 4.0 10.8 5.9 5.9 6.5 5.5 11.1 14.3 8.3 8.8 1.9 9.4 9.0 4.1 14.0 23.8 5.5 2.9 5.9 5.8 5.7 24.6 3.1 6.0 6.8 1.8 2.5 4.0 5.9 10.1 12.2 3.3 3.2 13.8 9.3 12.2 14.4 7.0 1.2 41.0 14.2 4.4 0.6 9.9 5.6 23.8 5.6 13.0 4.2 1.4 15.0 5.0 13.4 3.9 16.1 8.7 17.1 11.7 0.9 5.3 3.2 6.8 7.9 7.8 9.8 28.7 19.5 26.4 3.8 5.8 5.2 28.8 7.8 9.8 7.7 6.9 4.5 4.7 12.0 7.3 2.1 3.2 4.7 1.4 35.0 6.1 11.0 11.9 25.2 9.6 7.7 10.0 4.7 17.9 10.8 9.7 26.9 46.4 11.6 6.5 8.1 20.4 33.6 5.8 12.8 12.6 11.2 30.0 24.2 15.1 21.3 2.0 11.7 5.5 9.9 6.0 9.9 7.2 16.2 19.1 6.2 5.5 6.9 2.2 0.8 3.0 1.8 0.4 3.6 10.7 3.3 2.6 0.5 7.4 3.5 3.0 1.6 1.5 0.9 9.1 4.1 0.7 5.9 6.5 14.3 8.3 5.8 5.7 1.8 2.5 3.2 0.6 5.6 3.9 2.8 19.2 3.6 9.8 17.0 11.6 3.2 11.9 4.6 3.6 9.4 7.6 0.5 4.3 8.0 35.0 18.8 1.7 6.0 10.7 9.8 17.0 66.0 5.0 2.1 3.0 13.8 5.7 101.2 11.7 2.3 2.5 5.6 4.4 4.5 3.2 2.2 2.7 3.3 0.0 73.8 12.4 14.2 1.0 5.2 125.5 2.5 1.3 3.6 14.0 4.3 2.0 8.2 9.5 8.5 14.6 12.1 0.4 43.6 2.8 46.2 4.1 4.8 8.7 6.6 2.3 3.0 22.0 22.9 20.4 20.0 1.5 5.9 0.8 10.3 3.2 C17orf107 ENSG00000205710 "Chromosome 17 open reading frame 107" Q6ZR85 17 4899418-4902934 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 16.6;pituitary gland: 27.0" "Cell type enriched" "Detected in many" 5 "Late spermatids: 288.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 9.0" "Immune cell enriched" "Detected in single" 7 "neutrophil: 2.9" "Lineage enriched" "Detected in single" 7 "granulocytes: 2.9" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 2.6;HMC-1: 3.2;hTCEpi: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA069713 Uncertain Approved Nucleoplasm NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA069713: AB_2686181" "prognostic favorable (5.06e-5)" "unprognostic (1.63e-1)" "unprognostic (2.43e-1)" "unprognostic (1.51e-2)" "unprognostic (5.83e-2)" "unprognostic (1.13e-3)" "unprognostic (9.61e-2)" "unprognostic (5.03e-2)" "unprognostic (4.15e-1)" "unprognostic (2.05e-1)" "prognostic favorable (8.61e-4)" "unprognostic (1.17e-1)" "prognostic favorable (2.68e-4)" "unprognostic (9.29e-2)" "unprognostic (2.65e-1)" "unprognostic (2.71e-1)" "unprognostic (3.12e-1)" 2.2 1.8 1.3 1.1 0.9 2.1 2.0 9.0 3.6 2.1 0.0 0.9 1.0 1.5 3.4 1.1 1.8 1.5 16.6 1.7 3.5 2.9 5.6 2.0 0.5 1.3 0.2 4.2 5.0 3.6 27.0 0.6 0.7 3.4 0.4 1.7 13.2 1.9 0.5 3.5 1.0 0.4 0.0 2.0 3.3 4.6 1.6 0.3 1.3 0.0 0.6 1.0 1.6 1.0 0.3 0.4 0.5 0.1 1.0 0.8 0.7 1.9 0.2 0.1 0.3 0.3 0.3 0.2 0.3 2.6 0.0 0.7 0.0 0.2 0.1 0.0 0.4 0.8 0.4 0.4 1.4 0.0 3.2 0.8 3.3 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.9 0.4 0.1 0.1 1.4 0.1 0.1 0.0 0.2 0.2 1.0 0.1 0.2 0.3 0.5 0.2 0.1 0.3 0.2 0.2 0.2 0.3 0.0 0.2 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.3 2.9 0.0 0.0 0.0 0.0 0.1 1.3 0.9 9.0 3.6 1.7 3.5 1.3 0.2 0.7 0.0 1.6 1.0 1.7 0.0 1.3 1.6 9.7 1.8 2.8 0.4 6.8 1.2 3.5 1.7 14.4 0.0 1.1 0.0 0.0 0.4 4.5 0.1 1.9 0.4 53.3 0.8 0.4 1.5 0.0 0.0 0.7 1.3 2.3 2.3 2.0 1.2 11.4 0.9 0.4 3.1 1.0 5.0 0.8 1.5 2.0 1.9 10.7 288.4 1.5 6.3 1.8 0.0 0.1 0.0 0.0 0.0 0.2 0.7 0.0 1.2 8.1 2.3 0.2 1.9 0.6 0.8 0.0 0.5 2.0 1.5 1.2 1.2 1.3 5.2 4.0 1.1 0.2 1.1 C17orf58 ENSG00000186665 "Chromosome 17 open reading frame 58" Q2M2W7 17 67991099-67996469 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 35.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 51.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 55.5" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 37.3" HPA023036 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA023036: AB_10601144" "unprognostic (1.41e-1)" "unprognostic (1.22e-1)" "unprognostic (6.66e-2)" "unprognostic (1.35e-1)" "unprognostic (1.00e-1)" "unprognostic (7.65e-3)" "prognostic unfavorable (8.99e-4)" "unprognostic (7.45e-2)" "unprognostic (2.20e-1)" "unprognostic (2.27e-2)" "unprognostic (6.22e-2)" "unprognostic (6.69e-2)" "prognostic unfavorable (1.31e-10)" "unprognostic (1.16e-2)" "unprognostic (1.04e-1)" "unprognostic (5.00e-2)" "unprognostic (1.01e-1)" 11.9 5.4 5.2 2.8 5.5 3.9 16.9 5.4 10.0 26.8 4.8 8.4 4.0 15.1 6.9 5.1 7.8 4.7 5.9 5.7 5.3 6.1 9.4 3.4 3.2 5.4 5.3 4.8 4.8 3.2 2.0 35.6 5.1 5.8 7.3 8.9 4.3 3.6 3.5 3.5 4.6 10.9 5.5 2.3 6.8 3.0 5.2 2.1 6.8 7.3 7.1 8.8 7.6 5.5 9.8 9.5 9.3 11.6 6.6 16.6 7.3 4.0 11.4 6.9 11.2 5.6 12.4 13.0 8.9 3.3 12.1 4.9 21.3 8.6 16.6 23.5 21.5 8.4 3.2 17.8 10.4 7.2 14.9 9.2 10.2 6.7 15.4 7.7 32.7 11.2 18.2 19.6 6.7 13.1 1.3 9.5 10.7 23.6 10.0 3.1 10.2 17.4 8.7 6.5 6.9 12.5 6.0 55.5 20.8 11.4 15.8 8.2 6.1 5.8 5.9 4.2 8.5 38.9 30.9 11.6 14.8 12.6 10.5 8.6 2.8 5.0 2.2 2.9 0.7 3.0 0.8 1.7 3.9 0.5 0.3 0.8 1.1 2.7 5.0 0.1 0.4 1.8 5.2 5.5 5.4 10.0 5.7 5.3 5.4 5.3 5.1 5.5 5.2 5.5 21.6 0.0 1.7 6.2 3.5 4.8 5.5 5.6 7.4 8.9 31.0 21.8 4.7 12.8 6.1 11.0 10.4 28.6 4.1 10.5 23.5 10.1 0.9 21.0 40.5 16.3 3.6 8.4 5.0 9.3 21.7 51.6 19.9 19.4 12.7 3.8 14.3 18.5 16.9 5.0 4.6 15.0 10.2 9.7 21.5 2.8 3.7 7.3 8.8 2.8 18.4 31.9 12.3 3.0 4.6 10.7 10.0 5.3 7.0 11.6 10.9 19.7 16.5 15.6 6.6 36.2 14.1 7.3 6.0 20.7 8.4 15.3 4.1 8.3 10.1 7.6 C1orf159 FLJ20584 ENSG00000131591 "Chromosome 1 open reading frame 159" Q96HA4 1 1081818-1116361 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.9" "Cell type enhanced" "Detected in many" "Early spermatids: 60.9;Late spermatids: 124.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010019, HPA075399" Approved Approved "Nucleoli rim,Mitotic chromosome,Intermediate filaments" Yes No "Cluster 34: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli rim, Mitotic chromosome" "Intermediate filaments" "HPA010019: AB_1078885, HPA075399: " "unprognostic (2.79e-1)" "unprognostic (9.46e-2)" "unprognostic (5.43e-2)" "unprognostic (1.16e-1)" "unprognostic (2.12e-1)" "unprognostic (2.60e-3)" "prognostic unfavorable (9.58e-6)" "unprognostic (1.34e-1)" "unprognostic (3.09e-1)" "unprognostic (2.04e-2)" "unprognostic (9.29e-2)" "unprognostic (3.26e-3)" "prognostic unfavorable (1.77e-6)" "unprognostic (4.10e-2)" "unprognostic (1.81e-1)" "unprognostic (7.56e-2)" "prognostic favorable (1.62e-4)" 4.0 4.8 9.6 1.6 8.0 2.4 3.8 0.9 10.4 5.3 3.2 6.1 1.8 4.2 1.1 8.6 4.8 2.2 4.3 9.4 1.0 7.7 6.7 3.9 1.8 6.3 2.7 4.3 3.7 0.7 5.3 1.4 2.8 6.9 0.6 1.6 4.6 2.3 2.2 5.0 4.1 0.5 0.7 5.5 6.0 22.9 5.4 1.8 4.5 0.3 0.9 5.5 5.9 6.9 15.7 12.0 5.6 10.0 1.5 1.6 13.3 9.0 2.1 7.8 5.1 6.5 14.7 4.3 10.8 2.8 6.4 12.2 2.5 7.1 2.2 8.6 18.2 3.1 19.6 7.0 3.6 5.5 7.3 3.2 2.8 3.3 1.6 2.3 3.8 6.4 18.6 3.1 2.8 11.9 10.2 13.2 4.7 5.9 19.7 12.0 6.7 8.5 4.7 4.7 11.8 16.1 6.8 12.2 7.6 1.6 7.8 6.5 5.2 8.3 8.8 11.9 9.2 5.6 8.3 7.8 6.8 14.9 6.5 8.1 2.6 1.4 2.6 2.6 2.8 2.5 2.5 3.0 1.7 2.2 2.5 2.6 0.5 2.7 1.8 2.2 0.9 2.3 9.6 8.0 0.9 10.4 9.4 1.0 6.3 2.7 2.8 0.7 5.4 6.9 6.3 0.0 7.7 20.2 3.4 7.5 3.6 6.2 4.6 5.9 8.9 6.6 2.3 5.7 7.1 9.2 4.2 5.0 4.9 13.6 1.9 8.2 60.9 8.6 8.2 4.4 4.2 5.2 26.5 7.0 14.0 4.2 20.4 9.0 5.7 9.0 3.3 5.3 3.9 13.5 21.8 7.4 6.1 1.0 4.8 124.1 2.8 3.9 3.6 2.8 6.0 3.2 9.2 10.6 24.5 7.8 3.5 1.5 6.9 5.1 3.4 1.8 10.4 8.2 0.0 3.5 4.8 18.3 6.8 4.2 7.0 4.9 4.6 4.4 9.4 4.9 C1orf54 FLJ23221 ENSG00000118292 "Chromosome 1 open reading frame 54" Q8WWF1 1 150268200-150280916 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 115.7;Endothelial cells: 101.3;Kupffer cells: 145.7;Langerhans cells: 282.7;Leydig cells: 95.1;Peritubular cells: 104.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "myeloid DC: 103.5" "Lineage enriched" "Detected in many" 5 "dendritic cells: 103.5" "Cell line enhanced" "Detected in many" "AF22: 77.8;AN3-CA: 110.5;ASC diff: 86.1;ASC TERT1: 141.3;HSkMC: 102.1;HUVEC TERT2: 108.4;U-87 MG: 68.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA026518, HPA043874" Approved Approved "Plasma membrane" "Secreted to blood" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "HPA026518: AB_1845647, HPA043874: AB_2732511" "unprognostic (4.64e-3)" "unprognostic (6.81e-3)" "unprognostic (4.01e-3)" "unprognostic (5.69e-3)" "unprognostic (2.22e-1)" "unprognostic (1.72e-1)" "unprognostic (1.51e-2)" "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "unprognostic (3.45e-1)" "unprognostic (3.21e-1)" "prognostic unfavorable (2.43e-4)" "unprognostic (3.16e-2)" "unprognostic (8.06e-2)" "unprognostic (1.33e-2)" "unprognostic (4.48e-2)" 37.6 19.1 59.8 26.4 60.7 11.9 30.7 62.0 96.2 27.6 56.2 25.9 13.3 30.1 39.1 17.9 33.2 46.4 34.6 57.6 62.2 28.4 29.7 29.2 62.6 61.9 61.8 7.9 5.1 14.5 10.5 59.2 62.0 28.7 25.9 16.2 8.4 75.6 24.6 11.1 15.0 60.3 63.5 69.4 12.7 13.9 64.2 30.8 13.9 48.3 27.9 36.2 18.2 62.4 1.6 0.3 77.8 110.5 86.1 141.3 2.2 14.0 20.5 3.8 12.0 0.9 1.9 0.6 4.1 12.3 1.5 2.7 0.2 0.5 5.6 1.4 12.2 1.9 2.0 1.3 17.7 3.9 2.6 102.1 5.9 24.8 1.9 13.2 108.4 1.8 1.8 12.2 15.0 4.2 0.7 24.0 5.7 0.1 3.9 18.8 1.7 1.4 1.1 6.1 1.5 1.3 1.4 0.8 7.5 16.4 1.4 58.0 0.7 28.1 2.1 0.8 0.9 5.0 4.8 1.2 68.3 3.1 0.7 0.1 21.2 0.8 0.6 20.8 2.5 0.9 3.8 1.7 103.5 0.7 3.5 2.0 1.0 0.8 5.6 2.1 1.9 6.4 59.8 60.7 62.0 96.2 57.6 62.2 61.9 61.8 62.0 63.5 64.2 62.4 115.7 3.2 4.5 19.6 3.3 6.4 2.2 2.4 1.8 0.8 2.3 3.7 10.6 2.8 2.5 22.0 0.0 1.3 1.5 2.0 76.3 0.7 9.4 3.1 37.6 101.3 1.2 0.4 4.1 2.3 0.8 29.3 5.1 3.1 1.3 0.7 51.8 1.3 45.3 0.0 3.8 1.3 0.0 145.7 282.7 19.6 95.1 65.6 12.4 16.9 24.9 23.4 1.0 0.5 0.3 2.0 1.5 104.2 3.0 4.9 2.7 4.9 0.5 1.6 32.9 7.5 70.4 16.6 1.9 7.5 5.1 3.6 3.3 5.2 1.4 8.4 C1QTNF2 CTRP2 ENSG00000145861 "C1q and TNF related 2" Q9BXJ5 5 160347754-160370641 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 23.7;Leydig cells: 23.3;Peritubular cells: 29.7;Skeletal myocytes: 16.9;Smooth muscle cells: 22.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "basophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.3" "Cell line enhanced" "Detected in some" "RH-30: 34.4;U-138 MG: 15.1;U-2 OS: 8.3;WM-115: 6.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061290 Uncertain Approved "Golgi apparatus,Centrosome" "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Centrosome" "HPA061290: AB_2684468" "unprognostic (2.28e-2)" "unprognostic (5.61e-2)" "unprognostic (4.09e-2)" "unprognostic (4.53e-2)" "unprognostic (8.92e-3)" "unprognostic (6.20e-2)" "unprognostic (1.46e-1)" "unprognostic (1.94e-1)" "unprognostic (5.91e-2)" "unprognostic (8.33e-2)" "unprognostic (3.23e-2)" "unprognostic (8.32e-2)" "unprognostic (2.11e-5)" "unprognostic (5.40e-5)" "unprognostic (1.14e-1)" "unprognostic (6.75e-2)" "unprognostic (1.10e-2)" 2.8 0.6 0.9 0.7 0.9 0.1 1.9 1.2 1.3 4.7 0.1 2.5 1.2 3.3 1.1 1.4 2.3 1.8 3.9 0.9 0.8 0.6 0.4 2.4 0.3 0.3 1.3 1.3 0.3 0.2 0.5 0.8 0.2 1.9 1.1 0.2 1.3 1.0 1.9 1.4 2.3 1.8 0.2 0.6 2.0 1.8 2.5 0.1 2.1 2.1 0.3 2.1 2.6 0.8 0.3 0.0 0.5 0.1 0.0 0.0 0.0 3.9 5.3 0.9 3.3 0.1 0.9 0.0 0.1 1.4 0.6 0.2 0.1 0.4 0.2 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 34.4 0.0 0.0 0.2 0.0 0.8 1.0 0.1 0.2 0.1 0.4 0.1 0.2 15.1 8.3 1.5 4.4 0.1 0.0 0.0 0.5 0.0 6.8 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.9 0.9 1.2 1.3 0.9 0.8 0.3 1.3 0.2 0.2 2.5 0.8 2.0 0.0 0.0 0.0 0.0 6.5 0.2 0.2 0.6 0.8 0.3 0.4 1.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 1.9 0.1 0.0 0.1 1.0 4.2 0.0 0.0 0.6 0.2 0.3 23.7 0.5 0.2 0.0 0.2 1.1 0.0 1.1 0.0 6.2 0.1 0.0 0.0 6.2 0.4 23.3 0.5 5.4 1.0 0.6 0.1 0.0 1.0 0.3 0.1 0.1 29.7 0.0 0.1 0.0 0.0 0.0 0.8 0.0 16.9 22.8 0.1 0.5 0.6 3.8 0.8 0.3 2.1 0.1 0.3 C1QTNF4 "CTRP4, ZACRP4" ENSG00000172247 "C1q and TNF related 4" Q9BXJ3 11 47589667-47594411 "Predicted secreted proteins" Cytokine "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.0;pituitary gland: 17.1" "Cell type enhanced" "Detected in many" "Late spermatids: 51.7;Leydig cells: 46.0;Muller glia cells: 54.5;Peritubular cells: 38.4;Spermatogonia: 44.5;Theca cells: 39.0" "Group enriched" "Detected in some" 4 "glioma: 1.7;ovarian cancer: 2.5;testis cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "REH: 6.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041032 Approved Uncertain "Golgi apparatus,Vesicles" "Secreted in brain" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 14: REH - Unknown function" "Cluster 52: Non-specific - Transcription" "Golgi apparatus, Vesicles" "HPA041032: AB_10671170" "unprognostic (1.84e-3)" "unprognostic (1.58e-1)" "unprognostic (8.98e-4)" "unprognostic (8.19e-2)" "unprognostic (3.59e-2)" "unprognostic (2.26e-3)" "unprognostic (6.78e-2)" "unprognostic (6.11e-2)" "unprognostic (6.35e-2)" "unprognostic (4.00e-1)" "unprognostic (4.91e-4)" "unprognostic (1.22e-1)" "unprognostic (8.22e-6)" "unprognostic (6.02e-3)" "unprognostic (1.00e-1)" "unprognostic (2.80e-2)" "unprognostic (6.28e-2)" 1.7 1.5 7.9 0.0 33.0 1.1 2.2 13.2 17.6 5.3 0.0 3.9 0.1 5.8 0.0 0.5 4.2 0.0 1.0 7.5 1.1 1.4 0.9 0.7 0.0 6.0 4.9 12.0 0.4 0.7 17.1 0.0 2.1 2.8 0.0 0.1 1.1 0.1 0.9 1.8 1.5 0.1 1.0 1.0 1.5 5.8 6.7 0.0 1.5 0.0 0.0 1.3 2.0 3.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.4 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 33.0 13.2 17.6 7.5 1.1 6.0 4.9 2.1 1.0 6.7 3.4 2.4 0.0 0.0 18.9 0.0 2.4 6.5 0.2 0.0 15.8 1.3 25.8 0.7 1.5 0.3 3.7 16.7 1.3 0.1 0.2 3.9 0.1 11.3 0.8 21.2 4.5 0.0 2.5 15.5 0.2 2.7 20.7 0.5 0.6 0.0 31.3 2.5 0.2 3.3 5.0 17.8 0.1 0.0 0.3 3.0 51.7 46.0 0.7 10.6 4.7 0.0 54.5 0.0 5.0 8.0 0.1 0.1 38.4 0.0 4.3 0.1 0.6 0.6 24.7 26.3 12.8 8.5 13.5 44.5 0.3 1.8 3.6 0.6 39.0 0.2 2.4 C7 ENSG00000112936 "Complement C7" P10643 5 40909497-40984643 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 735.4" "Group enriched" "Detected in many" 4 "Fibroblasts: 578.4;Hepatic stellate cells: 662.5;Leydig cells: 1058.5;Sertoli cells: 309.0;Theca cells: 503.1" "Cancer enriched" "Detected in all" 4 "pancreatic cancer: 73.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "ASC diff: 116.5;HHSteC: 155.1;HSkMC: 212.1;SH-SY5Y: 146.7" "Not detected" "Not detected" "Region enhanced" "Detected in many" "spinal cord: 13.7" HPA001465 Approved "Secreted to blood" NA NA 48000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA001465: AB_1078554" "unprognostic (5.01e-2)" "unprognostic (3.74e-2)" "unprognostic (7.40e-2)" "unprognostic (4.68e-3)" "unprognostic (5.35e-2)" "unprognostic (1.43e-3)" "prognostic favorable (5.89e-4)" "unprognostic (6.67e-2)" "unprognostic (3.45e-1)" "unprognostic (2.21e-2)" "unprognostic (1.33e-1)" "unprognostic (1.93e-3)" "unprognostic (2.24e-2)" "unprognostic (6.10e-3)" "unprognostic (1.12e-1)" "unprognostic (2.14e-1)" "unprognostic (2.06e-3)" 470.9 607.7 2.6 21.7 3.5 0.2 46.4 2.6 9.6 118.5 13.6 165.3 19.3 124.6 163.6 52.9 377.3 211.7 558.7 2.8 2.5 298.1 110.6 206.7 99.2 4.4 2.7 735.4 149.8 15.0 23.1 359.2 3.0 101.6 32.5 1.5 18.0 105.7 4.3 12.6 139.8 256.3 4.3 138.2 120.2 28.0 3.0 32.2 105.1 1.6 22.5 122.1 118.3 3.0 0.0 0.0 0.0 0.0 116.5 16.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 155.1 0.0 0.0 212.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 146.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.6 3.5 2.6 9.6 2.8 2.5 4.4 2.7 3.0 4.3 3.0 3.0 7.9 6.4 4.1 0.0 1.4 0.6 0.5 0.0 1.8 2.1 1.2 0.3 56.7 7.2 2.5 0.0 0.0 0.2 0.1 0.4 0.0 0.2 4.7 0.5 7.9 127.6 54.8 26.7 0.1 1.3 0.1 578.4 0.0 0.2 1.3 2.7 662.5 8.3 0.5 43.7 0.3 1.3 0.0 14.5 4.2 29.8 1058.5 1.5 0.0 58.1 0.6 3.7 0.0 0.0 0.0 0.9 0.9 18.0 1.0 1.3 0.2 0.1 0.0 0.9 309.0 2.2 23.7 2.6 2.5 6.5 0.6 0.3 1.2 503.1 3.0 0.8 CABLES1 "FLJ35924, HsT2563" ENSG00000134508 "Cdk5 and Abl enzyme substrate 1" Q8TDN4 18 23134564-23260467 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 70.2" "Cell type enhanced" "Detected in many" "Astrocytes: 258.2;Glandular and luminal cells: 54.3;Oligodendrocyte precursor cells: 163.3" "Cancer enriched" "Detected in all" 5 "melanoma: 38.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Cell line enhanced" "Detected in many" "SK-MEL-30: 154.3;U-266/70: 216.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073649 Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nuclear bodies" "HPA073649: AB_2732233" "unprognostic (1.27e-1)" "unprognostic (2.03e-1)" "unprognostic (1.97e-1)" "unprognostic (4.24e-3)" "unprognostic (1.56e-1)" "unprognostic (2.56e-3)" "unprognostic (3.24e-2)" "unprognostic (1.10e-3)" "unprognostic (1.42e-2)" "unprognostic (1.55e-1)" "unprognostic (1.08e-1)" "unprognostic (1.01e-1)" "prognostic favorable (4.71e-6)" "unprognostic (1.00e-1)" "unprognostic (1.60e-1)" "unprognostic (4.80e-2)" "unprognostic (7.81e-2)" 17.1 3.3 63.9 2.1 67.9 2.6 13.8 36.8 54.8 6.9 17.1 5.2 7.5 9.4 3.2 6.9 10.9 5.2 4.6 44.9 53.5 13.1 9.9 21.5 2.8 39.6 59.0 3.7 3.0 21.9 4.0 10.4 40.8 3.7 5.1 8.0 22.3 4.5 1.5 17.2 6.7 6.6 31.2 3.7 14.5 3.5 70.2 4.9 15.0 1.8 2.3 5.4 7.8 33.3 13.1 14.4 11.8 0.9 7.1 0.3 20.4 3.1 17.3 4.2 2.5 9.5 23.0 0.7 13.3 14.9 42.3 11.4 9.0 2.3 3.2 0.3 19.4 1.0 38.7 37.1 6.2 2.5 1.0 4.2 2.1 5.3 6.1 26.8 47.1 2.3 0.5 16.2 11.7 30.2 0.1 8.8 7.5 64.5 46.6 3.1 42.2 50.6 21.2 31.5 11.2 8.2 26.1 32.5 154.3 8.3 52.4 7.2 79.3 47.9 0.5 1.6 3.8 216.0 88.9 27.4 0.2 19.2 16.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.1 0.0 0.0 63.9 67.9 36.8 54.8 44.9 53.5 39.6 59.0 40.8 31.2 70.2 33.3 2.9 22.4 27.4 258.2 3.8 5.1 2.0 1.4 5.2 4.1 9.2 6.7 1.4 7.2 2.3 3.7 29.2 0.9 1.3 8.5 1.9 1.1 2.0 11.6 4.4 6.0 3.5 1.3 19.2 2.3 1.1 4.1 10.2 54.3 0.0 14.8 25.0 9.3 16.6 0.0 22.2 4.6 0.0 3.5 3.1 3.5 0.0 4.7 28.4 41.2 0.0 1.4 0.0 163.3 1.4 2.4 5.2 6.0 3.6 0.6 6.7 14.3 1.8 18.7 0.0 5.0 2.1 0.2 3.2 1.6 6.7 0.3 1.4 0.5 2.1 2.2 CACNB3 CACNLB3 ENSG00000167535 "Calcium voltage-gated channel auxiliary subunit beta 3" P54284 12 48813794-48828941 "FDA approved drug targets, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 84.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 22.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.8" "Lineage enriched" "Detected in single" 10 "T-cells: 1.8" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 75.9;U-937: 109.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059515 Approved "Golgi apparatus,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 32: U-937 - Innate immune response" "Cluster 36: Stromal cells - Cell proliferation" "Golgi apparatus, Vesicles" "HPA059515: AB_2684047" "unprognostic (1.77e-2)" "unprognostic (4.84e-2)" "unprognostic (2.16e-3)" "unprognostic (2.12e-2)" "unprognostic (8.76e-2)" "unprognostic (2.68e-1)" "unprognostic (2.06e-1)" "unprognostic (3.60e-2)" "unprognostic (3.27e-2)" "unprognostic (2.24e-1)" "unprognostic (5.67e-3)" "unprognostic (1.04e-1)" "unprognostic (5.44e-3)" "unprognostic (6.31e-3)" "unprognostic (6.58e-2)" "unprognostic (1.98e-1)" "unprognostic (2.78e-3)" 10.1 3.9 67.9 2.8 69.9 1.3 9.0 56.8 84.2 33.7 44.1 18.1 4.1 31.1 8.5 21.5 19.6 7.2 8.4 72.6 56.7 12.4 1.9 11.8 1.8 50.2 56.2 43.7 4.5 5.1 12.3 5.8 53.4 13.7 8.2 4.7 13.0 9.1 2.8 11.5 10.8 23.1 49.9 6.1 9.2 8.6 59.6 7.6 9.6 5.9 4.1 14.5 20.2 58.7 17.3 13.2 21.1 46.1 26.8 18.0 12.9 16.8 39.4 25.6 14.5 4.5 13.4 2.2 21.5 30.7 4.4 17.2 21.6 19.5 10.1 18.4 5.9 8.5 11.7 0.6 11.0 1.7 9.1 11.7 10.6 10.2 5.5 75.9 31.1 18.6 1.2 7.2 16.9 42.6 22.1 2.2 13.3 18.1 10.9 24.0 5.0 6.6 19.9 31.6 32.9 31.8 5.5 37.1 12.0 18.6 25.2 7.7 27.3 15.5 21.7 7.7 9.5 7.1 3.5 0.7 12.9 109.9 5.0 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.6 0.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.8 0.2 67.9 69.9 56.8 84.2 72.6 56.7 50.2 56.2 53.4 49.9 59.6 58.7 5.6 3.2 4.3 1.0 0.5 2.9 3.2 5.9 4.0 3.2 8.7 5.7 2.8 1.5 5.1 1.8 4.2 0.8 2.1 12.6 1.9 9.5 1.0 10.0 22.0 5.9 10.2 0.8 15.1 4.3 10.4 7.9 6.1 7.1 1.3 12.0 3.6 0.2 1.6 0.0 4.5 9.5 16.2 0.6 2.9 2.7 13.4 2.4 1.8 3.7 3.7 1.0 2.1 2.0 1.1 10.4 4.6 10.9 1.3 2.9 8.7 0.7 9.4 1.0 0.0 1.5 12.2 1.6 8.1 9.6 5.1 1.1 3.5 6.1 14.4 1.9 CALHM2 FAM26B ENSG00000138172 "Calcium homeostasis modulator family member 2" Q9HA72 10 103446786-103452402 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 75.1;Fibroblasts: 38.2;Hepatic stellate cells: 48.2;Hofbauer cells: 53.7;Leydig cells: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 45.1;BJ: 37.7;BJ hTERT+: 37.5;fHDF/TERT166: 43.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA014706 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Mitochondria" Cytosol "HPA014706: AB_2243916" "unprognostic (2.45e-1)" "unprognostic (1.16e-1)" "unprognostic (3.01e-1)" "unprognostic (2.48e-1)" "unprognostic (3.92e-2)" "unprognostic (1.77e-1)" "unprognostic (1.10e-1)" "unprognostic (1.63e-1)" "unprognostic (8.85e-2)" "unprognostic (5.78e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.03e-6)" "unprognostic (8.59e-2)" "unprognostic (2.47e-1)" "unprognostic (3.56e-1)" "unprognostic (4.74e-1)" 49.7 18.5 7.2 12.5 6.5 2.1 38.9 6.3 9.0 54.4 7.0 18.4 6.5 58.1 5.5 12.2 43.3 21.6 34.2 7.0 7.3 10.7 4.5 23.2 13.7 8.0 6.4 48.1 7.1 3.1 7.3 10.0 7.8 21.1 4.3 0.4 14.9 10.6 9.7 17.9 19.6 15.9 7.7 35.3 13.8 11.5 8.0 5.6 21.6 11.1 6.1 33.9 39.3 7.9 11.0 7.5 1.8 2.4 27.3 45.1 9.1 37.7 37.5 11.2 15.7 3.3 5.3 3.3 4.2 43.2 0.7 5.0 3.8 0.0 2.1 0.4 21.5 7.8 2.5 0.6 12.4 1.3 0.7 15.6 0.0 3.3 0.1 20.8 13.5 8.3 1.8 19.8 7.5 25.0 3.0 3.7 4.8 2.3 6.7 9.2 3.0 7.5 1.0 0.9 5.3 2.3 1.5 6.2 2.1 0.8 1.2 2.5 24.5 3.6 4.4 12.6 2.7 3.0 7.6 3.8 31.0 24.0 0.8 70.0 91.9 1.8 83.7 178.4 69.6 27.7 56.5 69.7 152.1 7.3 10.8 42.3 3.6 62.9 214.6 17.8 82.7 85.6 7.2 6.5 6.3 9.0 7.0 7.3 8.0 6.4 7.8 7.7 8.0 7.9 18.2 3.2 0.6 1.0 4.9 5.4 2.9 0.6 4.0 0.1 3.4 4.4 3.3 1.5 0.0 3.7 0.0 3.1 11.3 0.1 0.0 4.2 1.0 1.4 19.8 25.5 1.2 5.7 2.3 0.2 75.1 38.2 1.5 2.1 8.8 11.4 48.2 0.6 53.7 0.0 0.5 0.1 2.0 28.8 18.8 2.5 45.7 21.5 8.8 2.8 17.3 0.2 33.0 1.0 0.2 0.1 0.1 16.1 3.1 0.8 0.0 0.3 0.0 0.1 19.7 16.8 27.9 0.8 0.9 0.8 3.8 19.2 19.4 6.0 0.0 1.0 CCDC151 "MGC20983, ODA10" ENSG00000198003 "Coiled-coil domain containing 151" A5D8V7 19 11420604-11435782 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 15.0;parathyroid gland: 9.8;testis: 10.4" "Cell type enhanced" "Detected in many" "Distal tubular cells: 29.4;Kupffer cells: 51.6;Muller glia cells: 58.9;Respiratory ciliated cells: 29.6;Spermatocytes: 22.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 2.0;T-47d: 4.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA054626 Enhanced NA NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 5: Muller glia cells - Visual perception" "HPA054626: AB_2682547" "unprognostic (1.50e-1)" "unprognostic (6.59e-2)" "unprognostic (2.05e-3)" "unprognostic (4.41e-3)" "unprognostic (1.35e-2)" "unprognostic (6.30e-2)" "unprognostic (4.41e-3)" "unprognostic (2.32e-2)" "unprognostic (2.22e-1)" "unprognostic (5.09e-2)" "unprognostic (6.76e-4)" "unprognostic (3.01e-1)" "unprognostic (2.63e-3)" "unprognostic (4.27e-2)" "unprognostic (1.85e-1)" "unprognostic (2.35e-1)" "unprognostic (2.05e-1)" 0.4 2.8 4.6 0.0 4.6 0.0 0.4 4.7 6.5 1.6 15.0 0.3 0.0 0.6 0.3 0.2 8.5 0.0 1.9 5.0 4.7 3.5 0.7 2.3 0.0 6.4 6.8 0.6 0.4 9.8 7.0 0.4 5.7 0.8 0.0 0.9 1.7 0.5 0.1 0.5 0.2 0.0 5.2 2.6 0.4 10.4 4.6 0.0 2.9 0.0 0.0 0.3 0.8 4.9 0.2 0.0 0.6 0.2 0.1 0.2 0.5 0.2 0.1 0.3 0.4 0.0 0.0 0.1 0.2 0.1 1.2 0.1 0.5 0.2 0.0 0.5 0.5 0.2 0.4 0.0 0.2 0.0 0.2 0.1 0.0 0.3 0.0 0.5 0.0 0.1 0.0 0.5 0.1 0.4 0.0 0.1 0.2 0.1 1.0 0.2 0.0 0.7 0.3 0.0 2.0 1.3 0.6 0.1 0.1 0.1 4.8 0.2 0.0 0.8 0.1 1.7 0.0 1.7 1.4 0.1 1.8 0.3 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.6 4.6 4.7 6.5 5.0 4.7 6.4 6.8 5.7 5.2 4.6 4.9 1.1 0.0 0.0 6.5 5.7 0.9 0.7 1.0 0.6 1.1 0.8 1.3 2.2 1.5 2.6 12.9 0.0 0.5 0.0 0.0 29.4 0.2 12.4 20.3 4.2 2.9 0.0 0.0 2.3 0.2 0.5 3.8 0.5 1.1 4.5 1.6 14.3 1.2 4.7 1.7 1.7 0.5 2.0 51.6 1.7 14.5 2.8 7.8 7.2 1.0 2.6 58.9 0.0 1.0 0.8 0.1 0.0 0.7 0.8 0.1 0.1 1.1 29.6 3.2 6.6 15.2 6.8 22.7 6.6 0.1 0.4 1.2 1.5 1.0 0.0 0.5 CCL8 "HC14, MCP-2, SCYA8" ENSG00000108700 "C-C motif chemokine ligand 8" P80075 17 34319435-34321402 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Smooth muscle cells: 104.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 6 "classical monocyte: 3.4" "Lineage enriched" "Detected in single" 6 "monocytes: 3.4" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.1;BJ hTERT+ SV40 Large T+ RasG12V: 1.0;EFO-21: 2.1;HSkMC: 3.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 32000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (7.51e-2)" "unprognostic (3.20e-1)" "unprognostic (1.90e-2)" "unprognostic (4.03e-2)" "unprognostic (8.00e-2)" "unprognostic (1.59e-2)" "unprognostic (1.52e-1)" "unprognostic (1.65e-1)" "unprognostic (9.97e-2)" "unprognostic (1.67e-3)" "unprognostic (1.46e-1)" "unprognostic (2.13e-1)" "prognostic unfavorable (1.05e-7)" "unprognostic (1.39e-1)" "unprognostic (1.88e-2)" "unprognostic (5.65e-2)" "unprognostic (3.41e-2)" 17.5 4.7 0.4 5.1 0.4 1.8 6.2 0.4 0.9 1.5 0.5 18.1 14.1 7.3 1.9 3.5 1.3 8.8 2.7 0.4 0.4 7.7 3.2 7.1 3.9 0.6 0.4 1.4 1.1 4.8 0.5 7.1 0.6 2.2 16.4 0.0 1.9 1.3 0.4 0.5 17.0 9.3 1.8 2.9 2.9 3.1 1.1 12.5 2.3 7.0 0.5 13.7 0.3 0.6 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 1.1 0.0 1.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.4 0.4 0.9 0.4 0.4 0.6 0.4 0.6 1.8 1.1 0.6 21.5 0.0 0.0 0.0 0.1 4.2 0.3 0.5 0.0 0.0 0.9 1.1 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 10.5 0.9 7.5 9.6 0.0 0.0 0.0 2.0 0.0 16.4 0.0 1.6 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 3.5 18.6 2.2 0.0 12.7 5.4 0.0 0.1 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 1.3 104.3 0.0 0.0 0.0 5.4 0.1 0.8 0.7 0.0 0.1 CCN1 "CYR61, GIG1, IGFBP10" ENSG00000142871 "Cellular communication network factor 1" O00622 1 85580761-85584589 "Predicted secreted proteins" "Cell adhesion, Chemotaxis" "Growth factor binding, Heparin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 256.5;Cardiomyocytes: 107.6;Cytotrophoblasts: 258.1;Extravillous trophoblasts: 529.9;Fibroblasts: 296.2;Syncytiotrophoblasts: 131.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebral cortex: 25.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 431.8;BJ hTERT+ SV40 Large T+: 422.0;EFO-21: 410.9;SiHa: 551.2;TIME: 541.3;U-251 MG: 642.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029853 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA029853: AB_10611822" "unprognostic (6.09e-2)" "unprognostic (3.25e-2)" "unprognostic (9.97e-2)" "unprognostic (8.90e-2)" "unprognostic (1.80e-2)" "unprognostic (3.91e-2)" "unprognostic (3.47e-2)" "unprognostic (1.56e-2)" "unprognostic (2.59e-1)" "unprognostic (9.95e-2)" "unprognostic (1.35e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.04e-3)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (3.74e-3)" 571.1 99.7 1.0 28.2 3.9 0.2 313.4 1.0 25.0 255.7 9.6 197.1 5.1 273.6 0.1 48.7 472.4 64.8 400.6 3.7 0.0 212.8 200.5 407.8 3.8 4.9 3.8 123.1 70.7 14.8 56.0 29.8 3.1 157.3 1.7 1.1 94.2 2.9 97.8 197.1 102.0 141.7 0.0 131.2 201.7 20.1 5.1 11.1 268.1 17.3 0.0 264.4 150.8 3.6 159.3 5.2 0.7 1.0 47.4 90.6 77.4 431.8 216.6 422.0 264.6 24.1 4.3 0.0 410.9 185.5 82.8 36.3 15.9 33.4 164.4 0.7 6.9 0.3 6.8 0.7 245.2 3.7 0.2 39.9 6.9 121.2 50.1 13.4 366.0 0.1 1.6 0.0 150.3 0.8 0.3 0.7 24.9 1.8 42.2 0.4 94.9 0.7 166.0 2.5 0.4 4.0 551.2 17.7 62.1 4.9 16.5 0.8 541.3 272.3 213.3 82.2 642.6 0.3 0.7 1.8 1.9 0.2 73.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.9 1.0 25.0 3.7 0.0 4.9 3.8 3.1 0.0 5.1 3.6 256.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.6 0.0 0.0 0.0 0.0 258.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 23.2 0.0 0.0 0.0 0.0 529.9 296.2 0.0 0.0 0.0 0.0 0.0 0.0 40.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 89.1 0.0 0.0 0.0 0.0 131.3 0.0 0.0 0.0 0.0 CDH19 CDH7 ENSG00000071991 "Cadherin 19" Q9H159 18 66501083-66604138 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.4;heart muscle: 37.1;intestine: 19.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 60.1;Melanocytes: 44.4;Oligodendrocyte precursor cells: 57.8;Oligodendrocytes: 192.6" "Cancer enriched" "Detected in some" 21 "melanoma: 16.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "SK-MEL-30: 35.9;WM-115: 63.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056332 Uncertain NA NA 320000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA056332: AB_2683102" "unprognostic (1.63e-2)" "unprognostic (2.63e-2)" "unprognostic (4.26e-2)" "unprognostic (4.10e-2)" "unprognostic (2.51e-2)" "unprognostic (3.14e-2)" "unprognostic (1.93e-1)" "unprognostic (3.79e-1)" "unprognostic (1.02e-1)" "unprognostic (4.39e-2)" "unprognostic (9.33e-2)" "unprognostic (2.25e-2)" "unprognostic (4.58e-3)" "unprognostic (8.16e-3)" "unprognostic (8.21e-2)" "unprognostic (1.56e-5)" 2.3 4.2 3.3 3.1 11.4 0.1 1.3 4.4 7.2 6.7 0.0 19.4 2.2 0.9 1.6 3.0 1.9 2.6 37.1 4.7 5.3 0.4 4.1 1.2 0.1 8.8 7.4 1.1 1.2 0.1 0.4 2.9 7.5 4.2 2.8 0.1 3.4 4.1 4.2 1.9 5.4 1.7 2.7 2.2 4.9 0.7 7.7 0.1 1.0 1.2 0.0 5.2 5.9 18.4 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.1 0.0 0.0 35.9 0.1 1.5 0.0 0.0 0.1 0.3 0.2 0.1 4.0 0.2 0.0 0.1 0.1 63.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.3 11.4 4.4 7.2 4.7 5.3 8.8 7.4 7.5 2.7 7.7 18.4 0.0 0.0 0.0 1.0 0.0 1.1 0.3 0.2 2.8 0.0 1.1 0.3 9.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.6 0.0 0.0 2.8 0.0 0.0 60.1 0.0 0.0 0.0 0.0 12.5 0.3 0.0 0.0 0.5 0.0 2.0 0.6 1.0 0.2 5.3 0.1 44.4 0.0 0.0 0.0 0.0 57.8 192.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.9 3.6 2.7 0.9 0.3 0.3 0.0 0.1 0.0 0.0 0.4 CDR2 "CDR62, Yo" ENSG00000140743 "Cerebellar degeneration related protein 2" Q01850 16 22345936-22437165 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 70.2;Spermatocytes: 50.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 8.4;NK-cells: 2.5;T-cells: 6.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018151, HPA023870" Uncertain Approved Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA018151: AB_1846457, HPA023870: AB_1846459" "unprognostic (7.89e-2)" "unprognostic (1.55e-1)" "unprognostic (5.23e-2)" "unprognostic (3.09e-1)" "unprognostic (6.59e-2)" "unprognostic (1.27e-2)" "unprognostic (5.76e-2)" "unprognostic (2.75e-1)" "unprognostic (2.55e-1)" "unprognostic (1.06e-1)" "unprognostic (9.86e-2)" "unprognostic (3.04e-1)" "unprognostic (2.04e-2)" "unprognostic (3.34e-3)" "unprognostic (1.38e-2)" "unprognostic (5.78e-2)" "unprognostic (1.67e-3)" 19.1 12.0 9.5 19.0 17.7 23.9 14.6 13.6 10.9 18.8 32.0 22.5 28.6 17.8 10.3 12.1 15.9 22.2 14.3 9.8 9.5 25.0 22.9 21.6 25.4 8.6 7.6 14.9 13.9 13.2 21.8 15.0 8.5 20.7 19.3 74.0 15.7 23.1 5.9 10.6 22.1 27.2 5.0 18.7 17.5 62.0 10.5 28.2 49.0 5.6 19.3 29.2 14.0 8.3 38.9 26.8 22.8 24.2 55.2 47.4 23.9 36.4 57.0 36.7 48.4 35.3 25.9 33.3 19.3 62.4 22.2 36.5 49.2 20.8 43.0 26.2 25.1 25.3 29.4 111.0 63.4 27.6 49.6 35.6 18.8 36.2 40.3 46.3 46.2 42.6 25.1 53.3 35.4 28.0 27.8 20.0 32.4 32.3 22.0 40.1 29.4 49.5 45.7 24.8 17.5 12.5 24.8 51.9 36.4 25.7 15.4 13.7 31.9 36.2 22.9 34.5 32.9 27.6 49.7 46.9 23.8 27.1 31.7 8.4 0.8 1.2 1.6 0.7 3.6 0.9 5.3 3.4 0.9 0.6 4.1 3.5 0.7 2.5 0.9 1.1 6.5 1.7 9.5 17.7 13.6 10.9 9.8 9.5 8.6 7.6 8.5 5.0 10.5 8.3 18.2 3.2 5.1 3.6 8.7 34.0 17.3 4.3 15.4 8.9 27.4 9.1 3.5 10.0 7.0 9.2 14.6 1.7 12.7 22.0 1.9 8.7 36.7 6.9 10.0 13.9 6.6 17.2 8.0 7.1 10.8 19.6 19.4 12.0 0.0 9.6 10.0 9.5 9.4 8.4 10.5 16.1 6.1 5.0 11.5 8.8 6.8 7.4 10.6 2.8 4.0 10.1 4.1 3.5 2.2 13.8 12.2 10.9 24.9 19.4 22.4 12.4 4.9 70.2 6.6 9.7 15.8 50.9 16.1 8.7 24.3 1.4 25.8 2.7 7.8 14.8 CEP126 KIAA1377 ENSG00000110318 "Centrosomal protein 126" Q9P2H0 11 101915010-102001062 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 143.7;Horizontal cells: 102.6;Respiratory ciliated cells: 138.5;Spermatocytes: 96.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 6.1;EFO-21: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038381, HPA038399" Uncertain Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "HPA038381: AB_10669780, HPA038399: AB_10670157" "unprognostic (7.61e-2)" "unprognostic (6.75e-2)" "unprognostic (9.07e-2)" "unprognostic (1.02e-2)" "unprognostic (9.31e-2)" "unprognostic (8.87e-2)" "unprognostic (1.55e-4)" "unprognostic (1.52e-2)" "unprognostic (5.77e-2)" "unprognostic (9.55e-2)" "unprognostic (7.72e-3)" "unprognostic (8.87e-2)" "prognostic unfavorable (5.00e-4)" "unprognostic (1.30e-2)" "unprognostic (3.41e-1)" "unprognostic (9.61e-2)" "unprognostic (6.99e-3)" 5.4 4.9 8.2 0.8 9.9 0.9 3.8 9.5 12.3 7.1 16.2 4.2 0.6 4.3 2.6 2.0 9.2 1.9 4.2 9.1 7.1 2.2 0.4 4.4 1.4 9.2 8.9 7.8 2.0 1.4 18.1 0.9 7.4 3.5 1.9 11.1 2.4 3.0 1.0 3.9 2.2 2.1 9.2 1.8 1.9 16.8 8.9 0.8 4.1 1.5 0.8 3.7 5.1 9.0 0.5 1.0 0.6 0.8 6.1 3.3 0.3 0.9 1.1 0.5 0.4 0.3 1.8 0.6 5.7 1.1 2.6 0.5 0.7 1.4 0.4 1.8 0.9 0.1 2.6 0.7 0.7 0.1 0.1 1.0 3.0 0.7 1.5 3.3 1.5 0.8 0.1 0.2 1.3 0.6 0.6 0.1 0.5 0.7 0.9 0.1 0.6 0.0 1.3 0.8 1.7 2.7 0.8 1.2 0.1 1.2 2.2 0.2 1.0 1.7 0.9 0.5 1.4 1.3 0.7 0.1 1.9 0.1 0.5 0.3 0.1 0.3 0.4 0.0 0.3 0.5 0.3 0.4 0.1 0.6 0.4 0.4 0.4 0.9 0.0 1.2 0.1 0.1 8.2 9.9 9.5 12.3 9.1 7.1 9.2 8.9 7.4 9.2 8.9 9.0 6.7 9.6 6.7 0.0 7.2 0.0 5.1 0.0 5.2 29.7 6.4 11.9 6.9 8.6 23.5 18.4 45.9 1.3 20.2 0.5 3.9 2.4 21.7 143.7 45.1 4.0 66.7 2.5 0.0 0.4 0.6 33.4 8.2 3.6 0.0 19.0 3.3 0.0 0.4 102.6 0.0 9.4 0.0 0.3 0.0 12.0 53.7 2.8 0.0 0.0 0.7 25.8 20.6 0.0 0.0 1.1 1.7 51.1 3.5 3.0 0.5 6.0 138.5 53.7 6.6 18.3 11.3 96.3 26.2 1.4 0.0 0.1 6.3 39.3 1.7 2.0 CEP164 "KIAA1052, NPHP15" ENSG00000110274 "Centrosomal protein 164" Q9UPV0 11 117314557-117413266 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, DNA damage, DNA repair, Mitosis" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 454.5;Early spermatids: 241.0;Late spermatids: 291.7;Rod photoreceptor cells: 268.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037605, HPA037606" Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 17: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Centrosome" "HPA037605: AB_10672908, HPA037606: AB_10672498" "unprognostic (1.92e-1)" "unprognostic (8.99e-2)" "unprognostic (7.98e-2)" "unprognostic (1.14e-1)" "unprognostic (1.47e-1)" "unprognostic (1.00e-1)" "prognostic unfavorable (2.40e-5)" "unprognostic (1.82e-1)" "unprognostic (3.14e-2)" "unprognostic (1.90e-1)" "prognostic favorable (5.93e-4)" "unprognostic (6.54e-2)" "prognostic unfavorable (2.89e-5)" "unprognostic (1.30e-1)" "unprognostic (1.51e-1)" "unprognostic (2.13e-1)" "unprognostic (7.93e-2)" 7.0 5.8 6.7 9.7 8.2 7.3 6.8 10.8 8.0 10.5 11.5 7.3 4.2 10.8 8.1 8.6 11.4 8.4 4.3 5.5 7.9 5.1 7.3 6.7 7.6 8.2 7.5 11.9 26.3 5.6 11.1 4.6 8.1 6.9 5.1 26.0 5.7 5.8 3.1 8.0 6.2 10.3 4.9 8.5 5.8 23.9 9.2 7.7 8.4 1.3 8.5 7.1 7.5 14.0 13.2 18.0 13.0 25.9 12.8 21.7 4.2 25.6 14.3 18.0 17.5 22.4 20.8 25.9 18.1 15.9 17.7 17.1 14.6 15.0 15.3 25.8 12.0 7.8 18.9 7.1 18.9 11.3 16.8 15.2 12.6 27.3 26.5 16.1 23.6 12.6 21.7 16.4 14.4 11.2 10.6 10.2 9.2 8.5 19.4 14.0 15.5 10.1 7.9 11.3 15.1 21.8 20.3 12.2 14.4 14.4 16.9 13.2 25.7 21.3 13.2 20.7 23.8 5.8 7.7 15.2 10.3 12.6 14.5 96.2 34.3 23.4 35.4 30.9 22.9 38.8 44.3 40.4 13.9 41.0 41.4 32.6 82.5 29.6 42.0 49.4 52.6 10.8 6.7 8.2 10.8 8.0 5.5 7.9 8.2 7.5 8.1 4.9 9.2 14.0 21.0 6.4 13.1 28.1 15.4 7.6 10.3 13.2 10.8 97.7 14.5 23.6 5.8 15.7 10.3 11.0 454.5 4.5 14.3 9.0 1.9 11.1 241.0 26.5 30.3 18.3 15.5 8.0 19.0 14.7 6.8 17.2 17.9 14.7 19.6 17.6 13.2 9.0 12.9 74.0 26.3 10.2 10.2 11.7 11.4 291.7 23.9 14.5 5.4 8.4 21.2 23.4 15.5 21.6 28.7 11.7 5.8 17.0 11.0 9.8 5.4 6.2 31.6 268.7 0.0 30.3 21.4 37.6 17.2 11.4 8.1 2.2 16.4 45.0 11.9 5.6 CFAP300 "C11orf70, FBB5, MGC13040" ENSG00000137691 "Cilia and flagella associated protein 300" Q9BRQ4 11 102047437-102084554 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 29.2;testis: 30.2" "Cell type enriched" "Detected in some" 4 "Endometrial ciliated cells: 142.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 17.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038585 Enhanced Approved Centrosome NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" Centrosome "HPA038585: AB_10795357" "unprognostic (9.70e-2)" "unprognostic (3.18e-1)" "unprognostic (3.02e-1)" "unprognostic (2.20e-3)" "unprognostic (1.05e-1)" "unprognostic (2.04e-1)" "unprognostic (4.16e-2)" "unprognostic (2.62e-1)" "unprognostic (3.03e-2)" "unprognostic (5.00e-2)" "unprognostic (2.66e-2)" "unprognostic (1.18e-1)" "unprognostic (1.77e-6)" "unprognostic (1.76e-2)" "unprognostic (8.68e-3)" "unprognostic (2.94e-2)" "unprognostic (6.73e-3)" 2.7 3.4 2.3 0.4 2.6 0.0 2.6 2.2 2.1 5.4 10.9 1.3 0.8 4.3 10.7 1.8 29.2 3.3 1.3 2.5 3.3 1.7 0.1 3.0 0.9 5.8 6.7 4.1 0.8 2.7 4.0 3.3 5.5 4.0 0.8 1.4 0.8 6.6 0.2 1.3 0.8 2.9 4.7 0.1 1.8 30.2 3.3 0.6 3.6 0.0 0.5 3.0 1.9 4.0 0.1 8.5 8.5 0.0 7.5 17.9 0.2 3.4 8.6 4.6 6.5 0.6 11.1 0.0 2.0 6.7 2.3 2.1 2.1 1.0 3.3 0.0 1.3 0.0 1.3 0.0 5.3 0.0 0.0 7.8 10.5 11.9 8.0 8.9 0.1 0.1 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.2 3.5 0.0 0.0 0.0 12.6 2.4 9.4 0.0 11.0 0.1 0.0 0.0 9.6 0.0 1.3 1.1 3.5 11.2 2.8 0.1 0.0 0.0 3.7 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.3 2.6 2.2 2.1 2.5 3.3 5.8 6.7 5.5 4.7 3.3 4.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.4 3.8 0.0 0.0 0.0 29.5 0.0 7.1 0.1 0.0 1.9 4.0 0.0 142.5 9.8 0.2 0.0 0.0 0.0 0.0 0.5 3.4 0.0 2.1 0.0 2.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.9 0.2 6.0 0.0 0.0 CFH "ARMD4, ARMS1, FHL1, HF, HF1, HF2, HUS" ENSG00000000971 "Complement factor H" P08603 1 196652043-196747504 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Host-virus interaction, Immunity, Innate immunity" "Age-related macular degeneration, Cancer-related genes, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 1676.3" "Group enriched" "Detected in many" 4 "Fibroblasts: 448.0;Hepatocytes: 1114.8;Leydig cells: 283.9" "Cancer enriched" "Detected in all" 9 "liver cancer: 151.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 18.7" "Lineage enriched" "Detected in single" 26 "T-cells: 18.7" "Cell line enhanced" "Detected in many" "HHSteC: 123.1;HSkMC: 119.5;hTERT-RPE1: 374.9;RT4: 227.0" "CAB016385, CAB016769, HPA038922, HPA049176, HPA053326" Supported Approved Vesicles "Secreted to blood" NA NA 396000000000 100000000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB016385: AB_627572, CAB016769: , HPA038922: AB_2676271, HPA049176: AB_2680663, HPA053326: AB_2682113" "unprognostic (2.40e-1)" "unprognostic (9.86e-2)" "unprognostic (1.22e-1)" "unprognostic (8.39e-2)" "unprognostic (5.40e-3)" "unprognostic (1.80e-1)" "unprognostic (3.75e-3)" "unprognostic (7.40e-2)" "unprognostic (1.06e-1)" "unprognostic (1.04e-1)" "unprognostic (9.08e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.92e-6)" "unprognostic (6.50e-3)" "unprognostic (4.49e-3)" "unprognostic (1.73e-1)" "unprognostic (1.37e-1)" 125.3 42.1 18.1 32.7 21.5 1.3 66.9 20.0 29.6 76.8 43.0 51.0 30.5 12.8 15.9 63.8 24.2 133.6 301.5 18.1 18.6 25.5 1676.3 70.8 27.4 19.3 19.0 165.1 14.0 6.4 16.0 26.1 19.9 23.0 80.2 4.3 126.7 24.0 21.1 74.5 52.1 32.5 19.5 13.9 46.9 14.3 21.6 12.1 102.5 84.0 25.9 149.9 27.0 21.1 0.0 64.9 0.0 0.0 96.5 54.7 0.1 25.8 63.1 3.5 13.5 0.1 11.9 0.3 9.6 0.1 0.2 2.2 0.0 23.6 2.6 1.3 0.0 20.0 74.7 0.0 123.1 0.9 0.3 119.5 0.3 18.4 7.9 374.9 79.2 0.0 74.4 2.7 89.4 0.1 0.5 0.1 0.4 0.0 0.1 0.2 89.8 21.0 0.0 227.0 0.0 0.1 0.4 0.0 0.1 0.6 0.1 0.0 5.6 73.6 0.9 0.8 0.8 0.8 0.0 0.3 13.1 0.2 5.8 0.0 0.1 0.0 2.0 0.0 18.7 0.0 6.6 4.0 0.2 0.0 0.4 1.5 0.7 0.0 0.0 0.0 0.0 1.1 18.1 21.5 20.0 29.6 18.1 18.6 19.3 19.0 19.9 19.5 21.6 21.1 73.9 9.6 17.6 0.7 4.2 44.2 63.6 140.6 14.2 2.4 1.3 3.4 10.9 35.8 141.1 5.5 0.0 0.0 3.1 0.1 0.0 6.2 2.6 2.3 3.8 49.8 0.0 52.6 0.6 0.8 0.0 448.0 8.6 1.9 3.8 6.9 47.8 1114.8 1.1 0.0 1.0 0.0 14.2 43.8 62.1 7.4 283.9 5.7 44.4 38.4 0.3 0.3 0.0 0.0 0.2 5.3 0.0 138.8 2.6 13.0 0.0 0.5 115.6 1.4 6.6 94.2 59.6 1.4 1.0 10.9 38.2 0.1 13.2 26.3 0.0 61.5 CHD3 "Mi-2a, Mi2-ALPHA, ZFH" ENSG00000170004 "Chromodomain helicase DNA binding protein 3" Q12873 17 7884796-7912760 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043368, HPA076524" Supported Supported "Nucleoplasm,Nucleoli,Centriolar satellite" No No "Cluster 27: Non-specific - Gene expression" "Cluster 51: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nucleoli" "Centriolar satellite" "HPA043368: AB_2678448, HPA076524: AB_2686804" "unprognostic (1.77e-2)" "unprognostic (8.01e-2)" "prognostic unfavorable (2.43e-4)" "prognostic favorable (7.68e-5)" "unprognostic (1.53e-1)" "unprognostic (8.11e-3)" "unprognostic (2.54e-1)" "unprognostic (1.11e-1)" "unprognostic (2.83e-2)" "unprognostic (5.25e-3)" "prognostic favorable (8.36e-4)" "unprognostic (9.11e-2)" "unprognostic (8.31e-2)" "unprognostic (3.98e-2)" "unprognostic (1.50e-1)" "unprognostic (8.90e-3)" "unprognostic (2.20e-3)" 28.2 29.3 19.9 35.0 27.9 42.7 28.4 0.0 39.9 71.6 0.0 55.3 16.7 63.9 31.2 35.1 56.8 27.8 21.2 35.8 7.0 38.3 5.7 32.4 41.3 4.9 2.4 60.0 34.8 44.7 47.7 16.6 1.1 68.7 22.1 19.0 40.3 38.0 8.0 32.7 34.6 45.0 3.1 31.5 36.3 20.9 8.0 58.2 44.9 9.1 36.7 41.2 42.8 21.4 44.9 108.7 61.6 81.2 72.2 60.9 32.8 51.7 66.1 40.8 43.5 21.1 36.7 122.8 38.3 73.0 34.0 59.6 117.7 52.5 53.0 65.5 67.2 62.7 148.5 2.7 38.3 17.8 112.1 79.2 27.5 55.4 36.9 108.7 76.9 54.1 41.5 2.0 38.8 42.6 48.2 19.6 9.8 45.3 40.3 137.8 82.1 19.3 40.0 107.7 41.9 56.3 126.4 47.9 24.6 16.9 55.7 27.1 99.7 89.4 68.8 22.3 72.5 8.8 1.6 68.3 46.1 47.4 77.6 1.7 2.6 3.3 4.1 1.4 3.6 1.1 4.2 4.0 1.3 1.2 4.6 3.1 2.8 3.2 3.2 3.0 2.5 2.5 19.9 27.9 0.0 39.9 35.8 7.0 4.9 2.4 1.1 3.1 8.0 21.4 20.9 32.1 63.2 10.4 19.6 36.6 47.6 21.1 65.4 60.7 43.8 34.2 14.3 17.2 35.2 80.9 8.4 16.8 57.3 39.8 17.6 22.9 11.3 48.6 51.9 29.4 56.8 19.1 20.6 23.4 20.5 39.9 31.1 70.7 39.9 59.7 22.9 2.7 9.0 45.4 25.2 17.0 12.2 24.7 34.7 18.5 44.4 26.7 8.8 6.5 43.7 12.4 59.8 12.1 2.5 20.9 10.8 57.2 17.4 55.5 10.9 9.7 24.8 17.3 26.3 31.8 43.5 25.5 46.8 52.8 20.5 16.4 62.9 52.0 30.3 60.3 CHRDL1 "CHL, MGC1, NRLN1" ENSG00000101938 "Chordin like 1" Q9BU40 X 110673856-110795819 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Differentiation, Neurogenesis, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 224.4" "Group enriched" "Detected in many" 4 "Astrocytes: 50.3;Fibroblasts: 83.8;Leydig cells: 41.0;Muller glia cells: 81.6" "Cancer enhanced" "Detected in many" "prostate cancer: 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "ASC diff: 537.8;ASC TERT1: 724.7;hTERT-RPE1: 341.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000226, HPA000250" Approved "Secreted in other tissues" NA NA 610000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA000226: AB_1078522, HPA000250: AB_1078521" "unprognostic (5.13e-2)" "unprognostic (6.31e-2)" "unprognostic (8.50e-3)" "unprognostic (2.48e-3)" "unprognostic (1.99e-2)" "unprognostic (1.72e-2)" "unprognostic (7.26e-3)" "unprognostic (1.42e-2)" "unprognostic (4.89e-2)" "unprognostic (5.54e-2)" "unprognostic (3.43e-2)" "unprognostic (3.56e-1)" "prognostic unfavorable (2.36e-4)" "unprognostic (4.75e-3)" "unprognostic (7.91e-2)" "unprognostic (5.01e-2)" "prognostic unfavorable (2.23e-4)" 188.3 7.3 7.1 26.2 14.5 0.9 69.8 8.3 14.1 38.8 6.5 74.8 10.8 148.2 20.2 58.0 53.5 47.9 22.0 9.4 6.2 15.1 1.8 76.3 24.4 4.4 4.5 7.1 12.5 84.9 6.4 21.9 4.0 141.6 35.5 55.6 23.3 224.4 6.1 17.5 22.1 101.3 4.3 16.0 17.9 6.5 5.8 10.9 37.8 34.9 11.7 28.3 20.0 6.3 0.0 0.1 3.3 0.0 537.8 724.7 0.3 7.6 3.3 18.8 16.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 23.0 0.0 17.6 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 58.7 0.1 1.6 0.0 341.2 0.0 2.0 0.0 0.0 0.1 0.0 1.0 0.3 21.3 0.0 0.0 0.0 0.0 0.1 3.0 0.0 1.7 5.2 0.0 0.0 0.4 1.4 0.0 0.0 0.0 5.8 4.2 60.4 7.8 0.1 0.1 0.0 5.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 7.1 14.5 8.3 14.1 9.4 6.2 4.4 4.5 4.0 4.3 5.8 6.3 8.4 0.0 2.7 50.3 0.1 4.8 0.0 0.0 0.6 1.5 0.3 0.4 2.3 0.0 1.8 1.8 0.0 0.1 0.1 0.0 0.0 0.3 0.3 0.0 1.0 13.8 0.0 0.0 4.2 0.0 0.1 83.8 2.0 0.2 1.3 0.3 2.2 0.1 0.2 0.0 9.3 0.0 0.0 0.0 8.1 1.4 41.0 1.1 8.8 1.0 0.0 81.6 0.0 13.6 0.2 0.0 0.0 9.1 1.4 0.3 0.0 4.1 1.5 2.9 0.0 2.7 11.2 0.2 8.2 0.3 4.4 0.1 1.0 0.0 0.0 0.1 CILP HsT18872 ENSG00000138615 "Cartilage intermediate layer protein" O75339 15 65194760-65211473 "Disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.9;Fibroblasts: 138.1;Leydig cells: 231.5;Peritubular cells: 57.6;Theca cells: 83.5" "Cancer enhanced" "Detected in many" "breast cancer: 30.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 4.2;ASC TERT1: 2.5;EFO-21: 1.1;HSkMC: 6.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA003195 Uncertain "Secreted to extracellular matrix" NA NA 13000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA003195: AB_1078524" "unprognostic (2.21e-2)" "unprognostic (3.43e-2)" "unprognostic (4.22e-2)" "unprognostic (7.18e-2)" "unprognostic (2.94e-1)" "unprognostic (2.28e-1)" "unprognostic (2.60e-1)" "unprognostic (1.14e-1)" "unprognostic (1.88e-2)" "unprognostic (3.00e-2)" "unprognostic (1.84e-1)" "unprognostic (1.27e-1)" "unprognostic (2.31e-13)" "unprognostic (5.10e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (4.68e-3)" 49.8 0.8 0.2 9.5 0.2 0.1 21.9 0.3 0.3 44.9 0.1 20.3 2.3 13.8 3.6 11.0 15.8 36.8 27.4 0.2 0.2 1.0 1.6 2.9 1.6 0.2 0.2 7.5 3.0 0.3 0.7 2.5 0.2 3.1 6.9 0.5 9.4 4.8 15.5 14.0 22.6 51.0 0.2 0.6 8.3 12.1 0.2 1.8 2.4 32.9 0.8 26.9 28.1 0.2 0.0 0.0 0.0 0.0 4.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 8.1 0.0 0.0 0.0 0.0 5.2 0.1 0.2 0.0 0.9 0.4 0.5 2.1 0.0 0.4 1.8 0.0 0.0 0.2 0.1 0.0 0.1 1.7 1.2 42.9 1.5 0.0 0.0 0.3 0.0 0.0 138.1 4.1 1.7 0.0 0.1 2.2 0.1 0.1 0.0 0.6 0.1 2.0 0.0 11.9 7.1 231.5 1.7 1.8 1.9 0.0 0.2 0.0 1.0 0.3 0.0 0.0 57.6 0.3 0.1 0.0 0.0 0.0 0.1 0.0 14.7 6.6 0.6 0.3 0.1 6.1 0.0 1.6 83.5 0.2 0.0 CLDN15 ENSG00000106404 "Claudin 15" P56746 7 101232092-101238820 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "adipose tissue: 65.4;intestine: 259.8" "Cell type enriched" "Detected in many" 4 "Proximal enterocytes: 594.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 45: Enterocytes - Digestion" "unprognostic (8.85e-2)" "unprognostic (1.48e-1)" "unprognostic (4.93e-2)" "unprognostic (3.66e-1)" "unprognostic (1.11e-1)" "unprognostic (6.81e-2)" "unprognostic (1.58e-2)" "unprognostic (1.03e-1)" "unprognostic (6.56e-2)" "unprognostic (1.79e-1)" "prognostic favorable (2.56e-4)" "unprognostic (2.02e-2)" "prognostic unfavorable (5.31e-5)" "unprognostic (9.98e-2)" "unprognostic (2.89e-2)" "unprognostic (9.64e-2)" "prognostic favorable (3.30e-4)" 65.4 3.9 8.8 7.3 10.4 13.6 20.2 9.4 11.0 14.9 6.3 22.3 259.8 11.1 2.2 7.2 16.3 7.3 8.6 8.6 9.1 23.9 22.2 10.7 9.8 11.4 9.8 18.5 7.8 2.0 6.8 5.9 11.3 11.4 7.9 8.8 6.5 2.6 3.6 11.2 183.9 4.4 8.4 22.6 10.0 8.3 10.1 8.7 9.3 1.3 7.0 9.8 11.6 18.2 3.3 10.1 5.3 8.4 8.1 6.5 3.6 3.2 4.0 3.9 5.6 7.3 3.8 11.0 5.6 2.1 6.4 6.1 8.8 1.8 3.8 13.8 18.5 5.1 6.9 9.0 7.1 5.7 10.6 6.2 8.8 5.1 6.7 8.3 3.3 10.9 24.3 17.4 3.0 11.7 9.1 32.6 4.1 4.9 6.9 12.3 4.5 9.3 2.3 4.1 5.1 18.1 2.9 5.5 16.4 7.2 5.1 11.4 4.7 12.8 11.0 19.5 3.9 18.3 24.9 11.7 3.6 14.9 7.5 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.3 0.0 0.1 0.1 0.2 0.2 0.2 0.1 0.1 0.3 0.1 0.2 8.8 10.4 9.4 11.0 8.6 9.1 11.4 9.8 11.3 8.4 10.1 18.2 27.3 3.2 1.1 4.9 5.2 6.8 5.4 12.9 5.2 20.4 7.5 6.1 1.2 18.6 8.2 22.0 31.3 5.1 6.3 18.9 13.7 5.6 17.1 8.6 3.8 22.4 12.1 16.8 1.5 6.5 3.8 17.2 9.2 7.1 0.0 5.2 7.5 10.6 2.7 15.2 1.4 55.7 16.2 4.6 7.5 4.1 15.2 4.0 7.2 4.7 5.1 4.4 10.3 0.5 10.5 6.6 93.1 2.2 1.2 6.1 594.4 3.5 10.1 20.2 6.6 6.4 5.1 5.8 7.2 3.4 5.3 5.1 5.5 3.2 120.6 3.9 CLMP "ACAM, ASAM, FLJ22415" ENSG00000166250 "CXADR like membrane protein" Q9H6B4 11 123069872-123195248 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 63.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 75.7;Fibroblasts: 95.1;Inhibitory neurons: 31.9;Peritubular cells: 57.9;Skeletal myocytes: 65.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 124.8;BJ: 171.8;BJ hTERT+: 160.3;fHDF/TERT166: 126.6;hTEC/SVTERT24-B: 129.1;hTERT-HME1: 155.6;U-138 MG: 232.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 310000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.63e-2)" "unprognostic (6.65e-3)" "unprognostic (1.06e-1)" "unprognostic (1.09e-1)" "unprognostic (3.46e-2)" "unprognostic (9.42e-3)" "unprognostic (1.31e-1)" "unprognostic (1.35e-3)" "unprognostic (9.66e-3)" "unprognostic (3.25e-2)" "unprognostic (4.02e-3)" "unprognostic (3.87e-2)" "unprognostic (9.78e-8)" "unprognostic (3.88e-3)" "unprognostic (1.26e-1)" "unprognostic (1.19e-2)" "unprognostic (1.69e-2)" 63.2 6.5 0.9 14.7 0.8 0.4 24.5 7.8 2.7 20.5 3.6 41.1 7.3 30.3 4.3 10.1 18.4 23.1 12.9 5.3 0.4 6.0 0.4 8.1 7.4 4.2 2.1 9.1 2.0 0.2 1.9 26.3 1.8 7.4 10.6 0.9 5.4 8.5 1.7 6.5 17.3 36.3 2.0 8.1 16.0 2.6 2.1 0.8 2.4 3.4 5.0 16.7 14.0 5.2 3.0 3.3 7.5 15.2 124.8 108.1 45.5 171.8 160.3 23.9 43.8 7.4 0.2 0.0 0.4 126.6 82.4 0.1 0.3 45.5 27.3 0.9 0.3 0.0 7.1 0.1 40.7 0.0 0.1 61.0 30.6 129.1 155.6 59.7 11.7 0.1 0.0 0.4 33.3 0.1 0.0 0.2 17.4 0.0 20.2 0.1 2.5 0.1 12.6 0.0 20.5 50.3 0.0 0.4 0.1 3.2 0.6 0.0 43.3 232.7 2.3 96.0 21.6 0.1 0.0 0.1 63.1 0.0 7.5 0.3 0.1 0.1 0.1 0.0 0.2 0.1 0.2 0.1 0.0 0.2 0.1 0.1 0.5 0.1 0.1 0.1 0.0 0.0 0.9 0.8 7.8 2.7 5.3 0.4 4.2 2.1 1.8 2.0 2.1 5.2 2.3 0.0 3.9 2.0 0.2 1.5 0.3 2.4 0.0 3.8 1.2 14.6 5.1 0.0 0.4 0.0 0.0 9.8 0.3 0.1 0.0 1.9 0.7 2.4 75.7 1.4 6.7 0.0 26.5 1.3 20.4 95.1 0.0 1.4 0.0 5.3 2.2 0.0 3.6 1.7 31.9 0.5 0.0 0.0 1.9 0.7 20.8 0.9 0.0 4.7 0.0 0.5 0.0 1.0 3.6 0.9 0.0 57.9 0.6 2.0 0.1 0.1 0.2 1.1 0.0 65.0 8.5 0.1 0.1 0.4 1.0 10.4 1.1 2.2 0.3 0.5 CMKLR1 RVER1 ENSG00000174600 "Chemerin chemokine-like receptor 1" Q99788 12 108288044-108339317 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 34.3" "Cell type enhanced" "Detected in some" "dendritic cells: 17.3;Hofbauer cells: 32.4;Kupffer cells: 69.6;Macrophages: 27.1;Microglial cells: 39.4;NK-cells: 30.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 14.5;plasmacytoid DC: 18.1" "Group enriched" "Detected in many" 22 "dendritic cells: 18.1;monocytes: 14.5;T-cells: 7.0" "Cell line enhanced" "Detected in some" "ASC diff: 11.9;ASC TERT1: 45.3;BJ hTERT+: 34.9;hTERT-RPE1: 13.6;LHCN-M2: 10.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047865 Uncertain NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA047865: AB_2680191" "unprognostic (1.78e-1)" "unprognostic (2.61e-2)" "unprognostic (8.83e-3)" "unprognostic (7.39e-2)" "unprognostic (2.44e-1)" "unprognostic (3.49e-3)" "unprognostic (1.69e-1)" "unprognostic (2.94e-2)" "unprognostic (1.69e-1)" "unprognostic (6.83e-2)" "unprognostic (1.06e-1)" "unprognostic (8.72e-2)" "unprognostic (2.96e-2)" "unprognostic (1.77e-1)" "unprognostic (1.83e-2)" "unprognostic (5.19e-2)" "unprognostic (1.14e-1)" 10.4 5.9 3.3 11.7 3.0 0.9 4.9 2.5 3.2 4.7 4.2 7.5 4.5 8.3 1.6 3.1 4.4 5.5 6.4 2.6 4.9 3.3 6.9 12.8 17.6 5.9 4.7 1.9 3.2 1.7 3.4 22.2 5.3 3.8 8.9 0.3 4.7 4.5 2.4 4.2 5.1 14.7 4.0 34.3 2.8 2.6 5.9 4.2 8.7 5.1 8.1 8.1 2.5 7.5 0.0 0.0 0.1 0.0 11.9 45.3 0.2 0.0 34.9 0.1 0.0 0.0 0.0 0.2 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.2 13.6 0.7 0.0 0.0 0.0 10.6 0.0 0.0 1.0 0.1 0.0 0.0 0.0 1.9 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.7 0.1 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 4.1 0.0 7.0 14.5 0.0 0.0 1.1 5.1 1.1 0.0 0.4 3.5 0.3 0.6 2.8 18.1 0.3 5.1 3.3 3.0 2.5 3.2 2.6 4.9 5.9 4.7 5.3 4.0 5.9 7.5 1.9 0.0 0.0 0.0 0.9 0.9 0.0 0.0 0.0 0.0 0.1 0.3 2.2 1.5 0.6 0.0 0.0 0.4 17.3 0.0 0.0 0.0 0.1 0.0 0.7 5.8 0.0 2.7 0.5 0.0 0.5 7.8 0.0 0.0 0.0 0.0 11.4 0.6 32.4 0.0 0.4 0.0 0.0 69.6 2.5 0.3 0.3 27.1 3.6 39.4 7.6 0.0 30.9 1.0 0.0 0.0 0.0 5.3 0.8 0.0 0.0 0.0 0.7 0.1 6.6 4.1 5.1 0.0 0.0 0.1 0.6 0.5 2.2 0.5 0.0 0.0 COL1A1 OI4 ENSG00000108821 "Collagen type I alpha 1 chain" P02452 17 50184101-50201632 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, FDA approved drug targets, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1331.8;gallbladder: 1211.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 2044.3;Fibroblasts: 1944.4;Leydig cells: 556.0;Smooth muscle cells: 1024.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 1689.5;BJ: 3428.1;fHDF/TERT166: 5206.1;HSkMC: 2490.3;U-138 MG: 2687.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 115.9" "HPA011795, HPA012111" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 80000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA011795: AB_1847088, HPA012111: " "unprognostic (1.61e-1)" "unprognostic (3.60e-3)" "unprognostic (8.29e-2)" "unprognostic (5.52e-2)" "unprognostic (7.74e-2)" "unprognostic (2.22e-1)" "unprognostic (6.01e-2)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.23e-2)" "unprognostic (2.55e-2)" "unprognostic (8.53e-2)" "unprognostic (9.90e-2)" "prognostic unfavorable (7.19e-12)" "unprognostic (2.74e-2)" "unprognostic (4.73e-2)" "unprognostic (7.26e-2)" "unprognostic (3.87e-3)" 312.1 39.9 1.8 272.8 5.3 4.5 184.9 1.3 15.9 1331.8 12.0 223.2 37.7 531.4 23.4 110.2 234.1 1211.3 126.6 1.5 1.9 34.7 29.7 139.0 78.1 3.2 1.4 377.3 39.8 14.1 80.5 503.5 2.0 137.5 46.5 0.4 51.3 98.6 21.2 362.0 86.6 801.2 2.2 46.9 109.9 38.2 17.3 14.4 50.8 13.0 21.1 616.3 342.2 6.7 6.0 5.0 16.4 3.2 702.9 1689.5 29.2 3428.1 915.8 826.6 517.6 64.2 14.6 0.6 7.8 5206.1 5.7 9.1 8.3 3.4 150.1 5.2 6.1 0.4 92.2 4.2 1309.3 1.2 0.8 2490.3 45.7 1016.2 4.6 126.9 0.5 4.8 2.2 0.4 425.4 8.5 1.4 1.0 17.0 10.7 10.5 6.1 2.1 2.7 3.9 0.2 2.0 8.8 5.6 5.0 0.2 245.4 39.8 0.6 1.5 2687.4 562.6 405.0 16.2 2.8 5.9 0.7 200.1 1.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 5.3 1.3 15.9 1.5 1.9 3.2 1.4 2.0 2.2 17.3 6.7 66.9 9.6 13.8 0.0 2.1 188.0 12.4 31.6 10.8 0.2 9.1 10.0 12.5 5.7 13.2 7.3 0.0 45.7 1.7 1.4 0.0 13.3 1.9 64.6 2044.3 33.4 3.0 0.0 0.1 4.2 45.5 1944.4 17.9 49.2 2.5 8.1 378.0 3.4 67.6 0.0 0.3 5.4 6.1 0.3 318.1 18.2 556.0 13.1 188.5 12.2 0.0 2.5 0.0 0.0 0.0 23.8 0.3 268.1 1.3 10.7 0.1 0.7 9.8 0.2 78.9 74.8 1024.9 4.0 2.6 4.3 163.5 111.8 29.4 57.3 2.9 9.1 COL1A2 OI4 ENSG00000164692 "Collagen type I alpha 2 chain" P08123 7 94394895-94431227 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 1831.7;gallbladder: 1378.0;smooth muscle: 1416.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 774.5;Fibroblasts: 2148.2;Glandular and luminal cells: 592.2;Leydig cells: 991.9;Peritubular cells: 501.0;Smooth muscle cells: 770.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 3899.2;ASC TERT1: 4637.0;BJ: 3995.6;BJ hTERT+: 2901.2;fHDF/TERT166: 13615.1;HSkMC: 4058.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 133.7" "CAB032650, HPA059738" Approved Supported "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 27000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB032650: AB_2082039, HPA059738: AB_2684116" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.32e-1)" "unprognostic (3.40e-2)" "unprognostic (2.86e-2)" "unprognostic (2.81e-1)" "unprognostic (5.15e-2)" "unprognostic (7.38e-3)" "unprognostic (2.01e-2)" "unprognostic (1.40e-2)" "unprognostic (5.83e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.35e-2)" "unprognostic (5.25e-2)" "unprognostic (1.15e-1)" "unprognostic (3.31e-3)" 514.8 52.4 6.8 266.2 9.3 2.0 314.5 7.1 17.4 1831.7 18.1 175.7 61.1 411.2 61.6 263.2 206.6 1378.0 275.4 6.0 6.8 40.8 27.4 229.5 91.6 8.7 6.7 297.2 57.1 32.5 33.5 624.6 7.9 196.2 141.8 1.6 60.2 232.3 51.6 424.6 103.2 1416.9 8.8 69.3 89.1 136.6 15.6 32.8 86.4 102.1 60.1 805.6 295.2 8.2 0.1 0.0 22.8 1488.5 3899.2 4637.0 1.3 3995.6 2901.2 642.6 850.5 0.0 2.8 0.3 2.7 13615.1 0.0 0.6 2.2 1.5 160.9 0.1 0.2 0.1 0.0 0.0 1018.6 1.1 0.5 4058.4 0.1 507.9 2.4 0.3 0.5 0.0 0.3 0.3 551.0 0.0 0.6 1.5 2.5 0.0 6.3 0.5 0.8 0.8 0.1 0.0 12.9 1.4 0.3 1.0 0.1 296.0 2.1 0.1 15.9 1626.3 0.8 1022.7 115.5 1.2 0.1 0.4 408.6 0.5 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 9.3 7.1 17.4 6.0 6.8 8.7 6.7 7.9 8.8 15.6 8.2 112.9 3.2 12.9 1.0 0.8 223.1 0.7 9.3 4.6 0.2 7.2 8.6 21.7 0.0 3.3 1.8 0.0 31.5 2.5 0.0 0.0 3.0 8.4 183.2 774.5 57.2 0.0 0.0 0.0 0.2 31.7 2148.2 26.5 592.2 10.1 16.4 258.8 1.9 116.9 0.0 0.1 0.0 0.0 1.0 394.5 45.1 991.9 16.7 238.3 97.4 2.6 3.2 0.0 0.0 0.2 5.2 0.0 501.0 4.5 1.0 0.0 0.5 0.8 0.4 302.4 249.9 770.7 9.9 4.5 6.2 187.4 70.7 30.6 214.8 0.0 0.8 COL4A4 CA44 ENSG00000081052 "Collagen type IV alpha 4 chain" P53420 2 227002714-227164453 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Collecting duct cells: 46.0;Cone photoreceptor cells: 56.3;Granulosa cells: 62.6;Muller glia cells: 78.6;Oligodendrocyte precursor cells: 55.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 4.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "memory B-cell: 4.1" "Lineage enriched" "Detected in single" 5 "B-cells: 4.1" "Cell line enhanced" "Detected in some" "HeLa: 34.3;hTERT-RPE1: 27.2;Karpas-707: 8.9;RPTEC TERT1: 14.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (7.31e-2)" "unprognostic (7.56e-2)" "unprognostic (6.65e-2)" "unprognostic (4.88e-5)" "unprognostic (1.12e-1)" "unprognostic (2.92e-2)" "unprognostic (8.50e-3)" "unprognostic (5.14e-2)" "unprognostic (1.44e-1)" "unprognostic (1.69e-2)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "prognostic favorable (2.30e-13)" "unprognostic (1.53e-2)" "unprognostic (2.65e-1)" "unprognostic (1.30e-1)" "unprognostic (4.15e-2)" 1.0 6.9 1.3 2.1 1.1 0.1 0.7 0.9 0.9 0.5 14.2 0.9 0.9 2.0 7.2 1.1 2.1 4.4 9.2 1.0 1.3 14.0 1.6 8.3 2.8 3.1 2.2 2.0 5.5 0.6 10.2 0.3 2.6 4.5 0.8 8.4 0.7 8.3 6.9 0.3 2.4 1.6 1.5 1.9 1.2 1.3 4.4 0.9 9.9 5.7 4.5 2.9 0.9 1.3 0.0 0.8 0.0 0.0 0.1 0.2 0.0 0.3 0.2 0.1 0.6 0.0 0.7 0.0 1.7 0.0 0.7 0.1 3.1 1.1 0.2 0.0 3.4 0.0 34.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 27.2 0.0 1.1 0.0 8.9 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.9 14.5 5.6 0.8 0.0 2.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 2.7 0.0 0.3 6.7 5.3 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.3 0.0 0.0 4.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.3 1.1 0.9 0.9 1.0 1.3 3.1 2.2 2.6 1.5 4.4 1.3 2.0 73.7 24.1 3.6 11.1 0.5 0.4 0.2 0.0 29.1 0.5 1.3 3.5 8.6 6.2 46.0 56.3 0.0 1.4 0.1 1.9 0.3 0.8 0.3 1.8 5.2 1.2 0.0 2.5 3.8 0.0 8.1 1.5 0.9 0.0 62.6 2.5 0.7 0.1 0.0 10.4 0.1 2.0 0.3 1.5 4.3 25.1 0.8 0.0 12.2 0.0 78.6 0.0 55.3 3.4 4.1 0.1 27.1 14.9 0.2 0.0 3.6 0.0 8.5 0.0 16.8 8.6 0.1 0.6 0.2 0.0 0.0 1.4 0.9 0.3 0.1 COL5A2 ENSG00000204262 "Collagen type V alpha 2 chain" P05997 2 189031898-189225312 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 186.0;Excitatory neurons: 185.2;Fibroblasts: 145.7;Skeletal myocytes: 76.4;Smooth muscle cells: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 447.8;BJ hTERT+ SV40 Large T+ RasG12V: 382.4;fHDF/TERT166: 430.3;HSkMC: 340.2;SuSa: 373.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 820000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (7.45e-2)" "unprognostic (6.44e-3)" "unprognostic (1.22e-1)" "unprognostic (9.31e-2)" "unprognostic (2.01e-1)" "unprognostic (1.13e-1)" "unprognostic (6.28e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (5.97e-2)" "unprognostic (1.78e-2)" "unprognostic (4.44e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.53e-10)" "unprognostic (4.57e-3)" "unprognostic (3.76e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (3.58e-4)" 61.0 4.8 2.3 42.5 5.7 0.2 25.7 0.0 15.6 83.4 3.1 48.7 10.0 43.4 32.7 23.6 21.2 81.9 19.5 17.6 0.8 6.3 12.4 26.1 9.3 2.0 17.4 25.2 7.1 7.5 7.3 111.5 3.8 14.8 25.4 1.6 7.4 12.8 7.8 12.9 22.8 98.3 1.9 10.0 21.5 6.8 1.0 4.7 9.8 26.8 10.3 57.3 29.7 2.5 0.4 93.5 143.9 67.5 212.0 285.3 0.8 213.7 242.3 447.8 382.4 63.2 0.7 0.2 2.2 430.3 23.2 1.6 4.1 2.3 153.3 0.9 1.3 1.0 2.1 0.6 282.6 0.6 0.4 340.2 7.8 129.8 45.3 92.2 108.5 0.9 0.5 0.4 109.1 2.4 0.3 0.3 20.9 0.9 124.3 0.5 33.9 0.4 0.5 24.9 2.0 1.4 5.2 2.5 5.2 373.0 2.1 0.2 91.6 212.8 22.9 52.6 44.6 0.8 0.4 0.6 32.2 0.1 235.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 5.7 0.0 15.6 17.6 0.8 2.0 17.4 3.8 1.9 1.0 2.5 36.7 0.0 1.5 29.7 0.3 26.1 0.2 7.2 6.2 1.3 1.6 3.7 2.8 0.0 0.7 1.8 0.0 4.6 0.2 0.5 1.9 0.6 0.7 22.4 186.0 9.1 38.7 0.0 185.2 0.7 3.9 145.7 0.5 5.1 0.0 4.2 25.7 7.4 6.6 0.0 23.8 0.2 4.1 0.3 27.4 1.7 48.7 1.4 21.4 25.3 0.6 0.7 0.0 21.6 10.9 1.1 0.1 19.5 0.4 0.3 0.1 1.0 1.9 0.8 46.0 76.4 116.0 3.9 1.8 2.0 18.8 6.2 2.8 27.4 0.0 0.4 COLEC11 "CL-K1, MGC3279" ENSG00000118004 "Collectin subfamily member 11" Q9BWP8 2 3594832-3644644 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 54.2;liver: 143.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 37.4;Hepatic stellate cells: 89.3;Peritubular cells: 52.3;Proximal tubular cells: 127.1;Sertoli cells: 72.3" "Cancer enhanced" "Detected in many" "liver cancer: 13.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HHSteC: 135.7;SH-SY5Y: 111.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA035241 Uncertain "Secreted to blood" NA NA 130000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 85: Liver - Metabolism" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA035241: AB_10600701" "unprognostic (3.35e-1)" "unprognostic (4.73e-2)" "unprognostic (2.44e-3)" "unprognostic (2.31e-3)" "unprognostic (1.53e-2)" "unprognostic (1.40e-2)" "unprognostic (7.95e-3)" "unprognostic (5.85e-3)" "unprognostic (6.96e-2)" "unprognostic (2.04e-1)" "unprognostic (1.41e-1)" "unprognostic (6.96e-2)" "unprognostic (2.26e-1)" "unprognostic (9.27e-3)" "unprognostic (7.54e-2)" "unprognostic (1.46e-1)" "unprognostic (1.60e-1)" 13.8 40.6 1.0 0.9 1.0 1.9 3.3 4.8 1.9 1.8 6.9 2.8 3.5 1.2 0.4 1.6 4.4 54.2 46.6 1.4 0.9 24.8 143.1 2.4 1.9 1.3 0.5 46.4 13.8 1.2 5.8 2.4 1.3 3.3 0.6 0.5 0.6 1.1 0.6 1.4 3.8 1.1 0.4 3.8 3.1 7.4 1.1 4.0 17.0 0.8 0.2 7.1 1.0 1.3 0.2 1.4 0.7 2.5 0.0 0.0 11.7 0.7 0.0 0.3 0.2 0.7 0.2 0.3 4.0 0.1 0.4 0.4 0.1 0.4 0.3 0.2 0.8 0.6 1.4 5.0 135.7 0.2 1.0 1.6 0.1 0.2 0.0 0.4 0.1 0.8 11.1 0.8 0.0 0.1 0.0 0.8 0.6 0.2 0.9 0.0 0.0 0.5 0.0 0.3 2.1 111.7 1.6 1.1 0.8 0.3 0.5 1.0 0.0 0.0 0.7 0.6 0.5 3.2 26.2 1.5 0.3 1.3 0.6 0.7 0.1 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.4 0.2 0.9 0.3 0.1 0.2 0.1 0.0 1.0 1.0 4.8 1.9 1.4 0.9 1.3 0.5 1.3 0.4 1.1 1.3 7.3 0.0 0.0 0.7 0.6 1.0 0.0 0.0 2.8 0.5 0.1 0.3 1.2 0.0 0.0 0.0 0.0 1.6 0.0 0.1 17.6 0.0 0.3 1.1 22.0 4.2 0.0 0.0 2.2 0.0 1.4 37.4 0.0 0.6 0.0 1.3 89.3 7.9 2.5 0.0 0.9 0.1 0.0 1.9 0.3 0.5 7.5 0.8 3.6 1.0 0.0 1.4 0.0 0.5 0.2 0.1 0.0 52.3 0.0 0.2 0.0 127.1 0.0 0.1 72.3 0.3 18.0 1.3 11.6 0.6 0.9 1.2 0.7 27.0 0.0 0.1 CORO2B "ClipinC, KIAA0925" ENSG00000103647 "Coronin 2B" Q9UQ03 15 68578993-68727806 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 83.4;retina: 45.2" "Cell type enhanced" "Detected in many" "Astrocytes: 57.1;Bipolar cells: 43.2;Cone photoreceptor cells: 37.5;Excitatory neurons: 96.6;Inhibitory neurons: 50.0;Oligodendrocytes: 146.4" "Group enriched" "Detected in many" 8 "glioma: 34.7;melanoma: 21.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.2" "Lineage enriched" "Detected in single" 13 "B-cells: 1.2" "Cell line enhanced" "Detected in many" "ASC diff: 26.8;ASC TERT1: 57.5;HSkMC: 41.6;hTEC/SVTERT24-B: 34.6;U-87 MG: 59.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017960 Enhanced Supported Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 37: B-cells - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Focal adhesion sites" "HPA017960: AB_1847167" "unprognostic (1.35e-1)" "unprognostic (2.63e-2)" "unprognostic (2.81e-3)" "unprognostic (4.71e-3)" "unprognostic (3.28e-1)" "unprognostic (8.11e-5)" "unprognostic (4.77e-2)" "unprognostic (1.24e-1)" "unprognostic (3.68e-2)" "unprognostic (1.81e-1)" "unprognostic (1.33e-3)" "unprognostic (4.12e-2)" "unprognostic (1.26e-1)" "unprognostic (1.10e-2)" "unprognostic (5.83e-2)" "unprognostic (3.59e-2)" "unprognostic (1.87e-2)" 10.9 3.5 44.1 2.0 60.9 0.7 7.2 62.1 66.5 7.2 28.2 5.9 1.2 7.5 2.2 1.4 27.5 4.7 16.4 48.1 43.5 9.2 1.3 5.1 1.8 62.4 62.7 14.9 2.2 0.5 3.5 3.2 58.0 4.3 1.5 45.2 2.7 4.9 2.6 4.1 2.8 6.3 51.9 3.9 3.1 1.0 66.5 1.3 6.1 4.5 0.8 4.1 3.7 83.4 0.6 0.8 26.2 2.2 26.8 57.5 0.0 13.7 15.0 2.3 3.2 0.3 3.0 3.5 1.6 2.3 3.7 0.2 1.0 0.3 9.5 0.0 1.2 0.0 0.0 1.2 9.8 0.0 0.4 41.6 0.3 34.6 2.0 20.4 1.0 0.0 0.0 0.1 24.4 0.1 0.0 0.1 6.5 0.0 0.1 2.2 0.1 1.2 3.7 0.0 15.3 0.3 0.2 0.0 7.8 4.8 0.0 3.1 0.2 7.8 8.9 1.7 18.3 0.0 0.0 3.5 59.2 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.1 60.9 62.1 66.5 48.1 43.5 62.4 62.7 58.0 51.9 66.5 83.4 2.8 0.0 0.0 57.1 1.1 1.0 0.4 0.0 0.0 43.2 0.1 1.0 1.5 0.0 0.0 7.3 37.5 0.0 0.0 0.0 0.0 3.8 0.4 2.1 11.6 3.0 3.6 0.0 96.6 0.6 0.0 8.0 0.0 0.3 0.0 0.9 6.4 0.0 0.2 0.0 50.0 0.3 0.0 0.3 0.7 0.7 7.8 0.3 7.2 11.2 0.1 12.5 0.0 17.1 146.4 0.6 0.0 0.4 0.0 0.1 0.0 0.1 8.1 21.4 6.6 1.4 2.1 0.2 0.5 0.1 0.9 0.0 0.1 7.5 0.0 0.1 CRACD "CRAD, KIAA1211" ENSG00000109265 "Capping protein inhibiting regulator of actin dynamics" Q6ZU35 4 56049073-56328625 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.1;intestine: 19.7;testis: 29.6" "Cell type enriched" "Detected in single" 11 "Cardiomyocytes: 3.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 26.7;SH-SY5Y: 56.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043249, HPA048148" Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA 59000 "Cluster 45: Intestine - Brush border" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "Golgi apparatus" "HPA043249: AB_2678388, HPA048148: AB_2680286" "unprognostic (1.65e-1)" "unprognostic (1.98e-1)" "unprognostic (7.74e-3)" "unprognostic (1.31e-1)" "unprognostic (6.04e-1)" "unprognostic (6.44e-2)" "unprognostic (1.98e-2)" "unprognostic (3.24e-2)" "unprognostic (1.34e-1)" "unprognostic (3.12e-2)" "unprognostic (1.11e-1)" "unprognostic (1.09e-1)" "unprognostic (8.05e-6)" "unprognostic (1.02e-1)" "unprognostic (6.54e-2)" "unprognostic (2.79e-2)" "unprognostic (2.93e-1)" 0.5 2.3 6.6 3.1 9.6 3.9 0.3 8.7 5.6 1.6 0.0 9.5 13.8 3.5 4.2 0.5 2.9 11.3 0.8 5.7 12.8 0.7 0.6 1.0 2.2 18.8 13.3 1.2 1.8 6.3 0.9 0.6 19.1 1.7 8.1 4.1 1.0 3.5 0.0 0.5 19.7 4.4 8.7 2.5 2.7 29.6 11.9 0.6 0.1 0.2 1.9 1.3 1.2 6.2 0.0 2.9 11.2 0.9 0.3 0.0 4.1 0.1 0.4 0.5 1.2 3.4 0.4 10.2 0.3 0.0 9.1 0.0 9.6 0.2 0.3 0.9 5.6 5.7 5.1 0.5 1.6 4.8 0.8 0.4 0.2 0.0 0.1 3.6 5.3 9.1 0.0 9.8 0.1 1.4 7.1 0.4 6.0 8.7 7.2 6.8 6.1 0.2 0.1 2.6 26.7 56.7 1.0 0.3 6.9 9.4 2.4 0.5 2.1 0.3 2.8 0.7 2.6 9.7 6.9 0.1 2.8 0.2 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 9.6 8.7 5.6 5.7 12.8 18.8 13.3 19.1 8.7 11.9 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 CREB5 "CRE-BPA, H_GS165L15.1" ENSG00000146592 "CAMP responsive element binding protein 5" Q02930 7 28299321-28825894 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.0" "Cell type enhanced" "Detected in many" "Adipocytes: 165.7;Basal prostatic cells: 192.2;monocytes: 163.9;Oligodendrocyte precursor cells: 229.7;Oligodendrocytes: 734.9" "Cancer enhanced" "Detected in many" "renal cancer: 5.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 198.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 198.8" "Cell line enhanced" "Detected in many" "HL-60: 62.5;Karpas-707: 25.0;U-2 OS: 25.7;U-2197: 28.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA050020, HPA061622" Approved "Nucleoplasm,Vesicles,Plasma membrane" NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Vesicles, Plasma membrane" "HPA050020: AB_2680993, HPA061622: AB_2684569" "unprognostic (3.59e-2)" "unprognostic (3.80e-1)" "unprognostic (1.06e-1)" "unprognostic (6.46e-2)" "unprognostic (1.01e-1)" "unprognostic (4.90e-3)" "unprognostic (2.01e-3)" "unprognostic (2.87e-1)" "unprognostic (3.31e-1)" "unprognostic (1.04e-1)" "unprognostic (3.49e-1)" "unprognostic (2.67e-1)" "unprognostic (4.91e-3)" "unprognostic (6.61e-2)" "unprognostic (3.95e-1)" "unprognostic (1.60e-1)" "unprognostic (1.52e-3)" 10.5 1.3 6.3 7.9 20.5 6.1 5.0 6.8 12.7 1.7 0.0 3.5 0.9 8.4 2.8 3.5 2.2 11.4 5.3 9.6 19.9 3.0 1.8 6.1 0.9 19.7 14.6 0.7 3.2 0.2 1.1 3.7 15.8 1.2 1.7 1.3 3.5 1.0 3.2 2.9 2.2 4.7 2.9 7.4 1.4 0.7 23.0 0.7 1.8 4.0 0.8 4.4 2.2 35.0 0.1 0.6 7.3 0.4 0.4 10.3 0.3 0.7 1.6 4.4 6.6 4.2 2.7 18.9 1.3 1.8 4.5 0.7 0.2 6.4 13.8 0.0 5.0 20.4 4.2 0.4 0.4 62.5 0.7 1.3 1.2 18.9 20.1 0.9 3.0 0.1 2.4 25.0 1.5 0.1 0.1 0.0 9.1 0.1 7.4 0.5 6.8 0.5 9.0 2.0 0.7 5.2 0.3 0.4 2.2 10.0 0.2 1.5 0.8 8.6 25.7 28.7 8.5 1.5 4.5 0.2 9.4 0.3 14.8 0.1 29.9 0.0 0.0 9.7 0.0 1.9 0.0 0.0 18.2 0.1 0.0 0.0 198.8 0.0 3.9 0.3 0.0 7.0 6.3 20.5 6.8 12.7 9.6 19.9 19.7 14.6 15.8 2.9 23.0 35.0 165.7 6.4 7.2 10.7 3.2 21.9 192.2 8.2 13.1 1.3 10.7 8.9 16.8 17.2 6.3 12.9 0.0 4.0 0.8 0.0 1.9 74.2 0.4 41.0 56.3 31.3 0.0 0.4 17.0 27.4 13.4 108.0 3.1 69.7 14.0 0.6 14.3 0.5 8.3 5.0 22.2 0.0 6.1 47.4 118.2 1.6 5.9 75.8 30.2 22.5 163.9 14.3 4.1 229.7 734.9 22.5 0.0 0.4 3.2 44.9 0.0 25.6 4.7 0.9 19.7 143.5 31.8 12.6 7.3 12.0 13.2 24.8 3.1 2.6 0.0 35.1 CRIP1 CRIP ENSG00000213145 "Cysteine rich protein 1" P50238 14 105486317-105488947 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 980.8;Endometrial ciliated cells: 1761.1;Proximal enterocytes: 2548.8;Respiratory ciliated cells: 1702.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 699.8;CAPAN-2: 415.5;HaCaT: 464.1;HDLM-2: 329.5;OE19: 1305.8;T-47d: 586.0" HPA042462 Approved Approved "Nuclear speckles,Plasma membrane,Centrosome,Cytosol" NA NA 29000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 11: Alveolar cells - Smell perception" "Nuclear speckles, Cytosol" "Plasma membrane, Centrosome" "HPA042462: AB_10794277" "unprognostic (2.97e-3)" "unprognostic (1.27e-3)" "unprognostic (1.34e-2)" "unprognostic (1.17e-2)" "unprognostic (2.39e-1)" "unprognostic (2.93e-3)" "unprognostic (4.33e-1)" "unprognostic (3.33e-1)" "unprognostic (3.20e-2)" "unprognostic (2.60e-2)" "unprognostic (2.87e-1)" "unprognostic (9.16e-2)" "unprognostic (3.26e-3)" "unprognostic (5.10e-2)" "unprognostic (2.66e-1)" "unprognostic (7.51e-3)" "unprognostic (2.14e-1)" 265.2 21.7 19.2 61.1 19.7 29.4 180.8 20.0 36.4 147.4 20.3 133.9 121.7 108.0 206.6 118.7 118.2 28.1 262.6 18.5 20.3 109.7 17.8 254.6 83.9 26.9 29.1 49.8 18.3 21.2 41.5 28.3 24.6 49.6 55.4 0.2 135.7 87.9 44.7 301.1 312.5 42.4 24.7 94.5 94.2 14.3 21.0 79.6 182.1 50.2 135.7 113.7 98.9 20.3 0.0 699.8 4.8 0.6 12.1 8.3 66.8 1.3 0.4 9.0 0.1 21.0 415.5 228.0 2.4 191.0 2.6 464.1 0.1 0.0 0.0 329.5 0.0 17.7 294.7 116.3 1.8 0.1 0.2 3.8 0.0 23.1 0.0 0.9 0.5 64.6 0.5 0.9 0.0 3.7 8.1 1.6 7.4 1305.8 36.4 181.3 0.0 45.5 0.0 0.0 18.5 1.3 2.6 1.2 0.0 0.5 586.0 106.4 1.5 0.4 0.4 5.5 0.0 0.3 0.2 17.9 0.0 0.0 0.6 121.8 218.6 313.1 209.2 214.4 135.1 697.0 442.0 222.1 442.9 384.2 85.4 100.2 13.9 323.5 283.9 291.3 694.8 465.6 19.2 19.7 20.0 36.4 18.5 20.3 26.9 29.1 24.6 24.7 21.0 20.3 50.2 980.8 256.2 0.3 350.7 186.5 1.2 79.5 67.2 0.0 88.1 18.3 1.0 2.8 501.3 51.5 0.0 2.1 287.8 360.4 1.9 20.5 3.6 1761.1 124.5 86.4 76.5 27.3 0.0 3.1 4.3 313.3 210.0 491.9 521.5 0.1 24.7 1.3 52.2 0.0 0.0 243.1 30.5 168.0 577.3 26.2 25.1 523.7 370.0 1.9 461.4 0.2 83.4 0.0 0.1 34.2 659.2 9.4 584.3 0.7 2548.8 2.5 1702.1 0.0 223.5 8.2 448.0 1.0 11.4 29.4 251.6 1.5 524.7 0.1 190.7 3.0 CRISPLD1 "Cocoacrisp, DKFZp762F133, LCRISP1" ENSG00000121005 "Cysteine rich secretory protein LCCL domain containing 1" Q9H336 8 74984505-75034558 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 29.4" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 36.1;Endometrial ciliated cells: 62.2;Oligodendrocyte precursor cells: 81.4" "Cancer enhanced" "Detected in many" "glioma: 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 134.4;SH-SY5Y: 72.0;SuSa: 27.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA024725 Uncertain "Secreted - unknown location" NA NA 8200 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" "HPA024725: AB_1847238" "unprognostic (2.16e-1)" "unprognostic (5.88e-2)" "unprognostic (4.01e-2)" "unprognostic (3.78e-2)" "unprognostic (3.85e-2)" "unprognostic (1.65e-1)" "unprognostic (2.09e-4)" "unprognostic (6.81e-2)" "unprognostic (1.58e-2)" "unprognostic (5.96e-2)" "unprognostic (2.35e-1)" "unprognostic (2.24e-1)" "unprognostic (1.65e-1)" "unprognostic (7.39e-3)" "unprognostic (2.38e-1)" "unprognostic (1.77e-2)" "unprognostic (1.23e-1)" 2.7 1.3 3.9 2.5 4.0 1.5 29.4 3.4 3.1 6.3 3.4 2.7 0.7 8.6 4.9 5.0 7.4 10.0 8.8 4.3 8.0 2.1 2.1 2.3 2.8 5.8 10.4 5.7 2.4 19.3 1.2 7.8 8.3 24.6 1.6 3.1 19.3 2.6 0.5 2.3 1.2 7.0 6.3 2.0 0.9 3.8 4.1 9.4 15.1 1.2 1.1 2.5 1.1 10.7 0.0 1.7 134.4 0.0 0.0 0.0 4.5 0.0 0.0 1.6 1.9 0.8 0.0 0.0 19.0 0.0 2.2 0.1 11.3 0.1 0.0 0.1 5.2 0.2 5.1 0.0 3.0 0.0 1.0 7.2 0.3 0.1 1.0 16.6 0.0 1.0 0.0 0.0 0.0 0.1 0.9 0.2 13.9 0.0 5.0 0.0 18.5 0.2 0.0 0.0 0.8 72.0 0.0 0.1 8.0 27.5 10.4 6.4 0.0 3.8 19.6 0.2 0.5 2.4 0.9 0.0 4.6 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 3.9 4.0 3.4 3.1 4.3 8.0 5.8 10.4 8.3 6.3 4.1 10.7 1.0 3.2 0.0 12.7 0.0 0.8 6.1 1.4 17.6 1.6 10.3 36.1 0.4 0.0 5.4 1.8 0.0 22.7 0.3 0.0 0.0 0.0 15.3 62.2 4.9 3.2 0.0 3.0 15.7 0.0 3.8 9.2 0.0 22.4 3.8 1.8 23.6 0.1 2.0 0.0 11.1 0.0 0.0 0.9 0.0 1.5 4.1 0.4 7.2 1.9 0.0 8.8 0.0 81.4 0.9 0.0 0.0 1.5 0.0 9.4 0.0 0.2 22.5 0.9 0.0 0.4 1.5 1.3 6.0 2.5 1.0 12.0 0.4 6.3 0.0 2.3 CTSO CTSO1 ENSG00000256043 "Cathepsin O" P43234 4 155921580-155953912 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 37.1;HSkMC: 44.6;Karpas-707: 85.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002041 Approved "Intracellular and membrane" NA NA 25000 "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA002041: AB_1078408" "unprognostic (3.96e-3)" "unprognostic (1.62e-2)" "unprognostic (1.03e-1)" "unprognostic (1.33e-2)" "unprognostic (9.10e-3)" "unprognostic (2.55e-1)" "unprognostic (3.80e-3)" "unprognostic (2.07e-1)" "unprognostic (6.62e-2)" "unprognostic (1.33e-1)" "unprognostic (2.20e-1)" "unprognostic (1.05e-1)" "unprognostic (7.55e-2)" "unprognostic (4.87e-3)" "unprognostic (4.73e-2)" "unprognostic (1.11e-1)" "unprognostic (1.79e-1)" 19.1 31.5 8.0 17.8 8.0 5.0 31.9 6.2 11.8 36.7 7.9 19.6 32.8 37.2 36.1 16.7 36.9 40.7 20.2 7.8 7.6 34.5 98.8 36.8 24.5 7.1 7.5 28.0 19.9 24.5 9.6 41.2 6.9 29.8 23.2 5.2 22.1 32.2 6.7 10.0 34.0 30.7 7.0 39.7 15.5 9.4 7.4 14.1 34.5 17.8 17.9 28.0 15.4 7.6 0.8 0.6 4.1 3.7 17.3 37.1 0.2 1.6 18.3 3.3 5.7 0.4 14.4 0.2 1.2 6.8 1.2 0.1 0.2 0.1 2.6 1.6 0.1 0.4 0.5 0.2 18.1 1.4 0.2 44.6 3.5 2.2 1.8 25.6 3.5 0.7 0.3 85.8 11.7 0.7 1.1 0.4 0.7 0.6 0.7 4.8 0.5 1.0 16.8 7.5 0.5 4.3 2.4 9.3 2.3 2.0 4.2 2.6 3.0 13.3 0.7 0.4 2.3 8.3 0.2 0.2 24.4 0.3 18.6 5.3 0.9 0.6 1.2 0.7 3.0 1.2 1.4 0.8 0.4 1.5 1.6 2.0 0.7 3.0 0.9 1.0 3.3 1.4 8.0 8.0 6.2 11.8 7.8 7.6 7.1 7.5 6.9 7.0 7.4 7.6 29.3 38.5 20.8 15.0 19.9 10.5 13.1 11.3 12.0 10.4 20.1 13.0 5.0 44.3 14.3 25.8 2.1 20.5 19.6 15.6 13.7 24.6 0.4 20.9 34.6 28.2 6.7 8.6 1.7 20.7 7.7 51.5 8.6 27.3 8.8 25.0 43.2 58.1 16.3 5.0 1.7 7.9 8.2 29.2 23.7 1.5 30.4 21.4 30.2 7.5 26.5 17.0 22.6 36.7 5.4 12.7 6.3 25.2 7.0 17.5 21.1 10.7 14.5 1.9 19.7 34.0 24.6 0.3 2.1 5.9 9.1 10.5 14.5 14.3 6.6 9.5 CYBRD1 "CYB561A2, DCYTB, FLJ23462, FRRS3" ENSG00000071967 "Cytochrome b reductase 1" Q53TN4 2 171522247-171558129 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" "Oxidoreductase, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 221.2;Fibroblasts: 243.4;Leydig cells: 202.0;Peritubular cells: 221.5;Proximal enterocytes: 689.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 17.4;intermediate monocyte: 17.7;myeloid DC: 16.8;neutrophil: 9.8;non-classical monocyte: 13.7" "Group enriched" "Detected in many" 4 "dendritic cells: 16.8;granulocytes: 9.8;monocytes: 17.7" "Cell line enhanced" "Detected in many" "ASC diff: 1064.0;ASC TERT1: 453.8;BJ hTERT+: 408.2;HSkMC: 327.3;hTERT-RPE1: 276.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014757 Approved Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA014757: AB_1847374" "unprognostic (1.35e-1)" "unprognostic (1.57e-1)" "unprognostic (2.89e-2)" "unprognostic (4.87e-2)" "unprognostic (2.97e-2)" "unprognostic (3.11e-2)" "unprognostic (2.86e-1)" "unprognostic (5.44e-3)" "unprognostic (8.90e-3)" "unprognostic (3.57e-3)" "unprognostic (1.74e-1)" "unprognostic (1.71e-1)" "unprognostic (1.02e-3)" "unprognostic (1.93e-2)" "unprognostic (8.48e-2)" "unprognostic (2.77e-2)" "unprognostic (1.51e-2)" 166.7 97.5 32.6 24.4 38.8 18.3 148.7 33.9 34.1 140.0 32.6 68.7 197.7 100.2 49.7 70.6 88.2 153.7 128.6 28.2 45.9 32.0 21.7 129.9 33.8 45.2 38.7 180.9 21.6 12.0 26.1 38.1 40.5 70.6 39.0 22.2 63.7 76.7 23.3 85.0 233.4 87.9 35.6 30.6 53.3 23.8 35.9 27.9 231.0 82.8 30.1 84.3 90.4 43.0 24.8 18.1 10.1 19.2 1064.0 453.8 1.3 88.3 408.2 45.0 56.4 1.1 33.8 0.0 14.8 214.2 46.2 12.2 8.4 7.2 53.2 18.9 2.2 20.7 26.1 0.4 222.7 22.0 1.9 327.3 68.8 70.5 13.7 276.3 29.6 12.4 7.0 0.2 128.3 0.0 7.1 20.4 5.1 0.0 4.6 2.5 125.3 1.5 7.0 1.4 1.3 4.7 104.2 0.2 56.5 3.6 35.8 13.5 59.5 101.0 14.4 96.1 38.3 0.3 0.4 0.2 49.5 18.3 55.6 0.0 17.4 0.8 1.6 17.7 0.3 0.0 0.3 0.2 16.8 0.0 0.0 0.0 9.8 3.6 13.7 0.7 0.0 7.5 32.6 38.8 33.9 34.1 28.2 45.9 45.2 38.7 40.5 35.6 35.9 43.0 37.6 221.2 109.0 45.1 0.9 121.2 47.3 20.3 38.7 0.0 54.7 48.0 18.4 37.1 34.7 25.8 0.0 1.9 3.4 16.1 0.0 1.0 1.5 4.2 35.6 33.9 0.0 85.0 0.9 6.4 2.3 243.4 13.3 8.3 2.5 1.6 73.5 2.4 48.5 0.0 1.5 22.2 2.0 60.7 92.0 6.1 202.0 28.4 44.4 36.5 29.3 27.9 4.1 12.1 54.2 1.8 16.2 221.5 2.2 22.5 689.4 0.3 6.9 1.5 19.7 89.6 49.9 1.2 1.2 7.0 60.1 1.4 5.9 2.8 27.6 18.2 CYP27A1 "CP27, CTX, CYP27" ENSG00000135929 "Cytochrome P450 family 27 subfamily A member 1" Q02318 2 218781749-218815293 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "liver: 594.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 404.3;Hofbauer cells: 148.9;Proximal enterocytes: 206.3" "Group enriched" "Detected in all" 4 "liver cancer: 176.9;melanoma: 85.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 151.5;neutrophil: 126.3" "Group enriched" "Detected in many" 21 "granulocytes: 126.3;monocytes: 151.5" "Cell line enhanced" "Detected in many" "Hep G2: 299.6;HSkMC: 54.7;RPTEC TERT1: 78.5;SK-MEL-30: 103.6;WM-115: 42.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059155 Enhanced Approved Mitochondria,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Mitochondria Cytosol "HPA059155: AB_2683933" "prognostic favorable (1.05e-4)" "unprognostic (4.21e-2)" "unprognostic (2.34e-1)" "unprognostic (1.83e-3)" "unprognostic (3.71e-3)" "unprognostic (1.31e-2)" "prognostic favorable (8.62e-6)" "unprognostic (6.04e-2)" "unprognostic (1.73e-1)" "unprognostic (4.04e-1)" "unprognostic (1.25e-3)" "unprognostic (8.76e-3)" "unprognostic (1.09e-3)" "unprognostic (1.08e-1)" "unprognostic (7.51e-2)" "unprognostic (1.64e-1)" "unprognostic (1.36e-1)" 23.1 50.3 45.2 15.7 59.0 1.3 21.8 57.0 59.3 27.6 75.6 27.6 77.8 19.8 11.6 11.9 34.0 19.1 30.7 42.2 49.3 46.4 594.4 71.7 24.6 63.0 56.1 32.6 8.3 18.5 29.6 6.2 62.7 41.8 20.7 22.5 40.4 29.5 37.9 17.5 81.9 13.2 50.6 13.0 13.8 12.6 58.8 23.6 12.6 49.2 28.0 24.3 23.2 69.2 0.2 0.0 2.7 0.2 4.6 3.3 0.4 1.9 11.7 3.9 7.8 13.7 0.8 0.0 4.3 7.6 0.2 0.1 0.0 0.0 1.7 1.4 1.0 0.0 0.4 299.6 16.2 0.4 0.3 54.7 0.5 0.1 0.0 12.8 5.9 0.0 0.3 0.1 8.3 0.0 0.0 0.2 2.3 0.3 0.5 0.1 2.4 0.5 78.5 0.2 0.2 0.2 0.1 0.0 103.6 2.4 1.6 2.2 5.9 0.0 0.2 0.1 6.0 0.0 0.0 0.1 0.1 0.3 42.9 0.0 151.5 0.4 0.2 17.1 0.3 0.7 0.2 0.5 6.5 0.0 0.1 0.0 126.3 0.0 1.2 0.8 0.0 44.1 45.2 59.0 57.0 59.3 42.2 49.3 63.0 56.1 62.7 50.6 58.8 69.2 10.6 3.2 28.9 33.6 0.9 5.2 52.4 8.5 21.6 15.3 12.7 18.8 5.1 17.2 11.3 3.7 27.1 0.7 0.5 37.0 9.8 12.1 1.0 12.6 4.3 10.3 24.5 8.4 2.2 12.0 0.7 35.4 2.6 14.8 2.5 1.9 19.6 404.3 148.9 10.1 3.9 20.0 4.1 18.2 5.1 1.0 47.5 104.3 49.8 15.0 92.4 28.7 0.0 26.7 108.5 9.7 44.0 26.7 0.0 43.3 206.3 76.9 21.4 14.1 0.0 12.8 7.2 0.7 0.1 3.2 3.1 1.2 2.3 1.2 30.3 20.4 CYRIA "CYRI-A, DKFZP566A1524, FAM49A, FLJ11080" ENSG00000197872 "CYFIP related Rac1 interactor A" Q9H0Q0 2 16549459-16666331 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 46.4;Extravillous trophoblasts: 102.6;Hofbauer cells: 37.1;Macrophages: 24.0;Syncytiotrophoblasts: 150.0" "Cancer enhanced" "Detected in all" "thyroid cancer: 18.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 53.1;HUVEC TERT2: 43.1;RH-30: 95.6;SK-BR-3: 28.2;TIME: 34.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017847, HPA060398" Approved Approved Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB017847: , HPA060398: AB_2684275" "unprognostic (3.45e-1)" "unprognostic (1.83e-2)" "unprognostic (6.50e-2)" "unprognostic (1.94e-3)" "unprognostic (1.88e-1)" "unprognostic (7.78e-2)" "unprognostic (8.61e-2)" "unprognostic (3.83e-2)" "unprognostic (2.61e-1)" "unprognostic (2.00e-2)" "unprognostic (5.74e-2)" "unprognostic (8.38e-2)" "prognostic unfavorable (1.83e-6)" "unprognostic (1.32e-2)" "unprognostic (3.43e-2)" "unprognostic (3.82e-2)" "prognostic unfavorable (4.46e-4)" 13.9 11.0 29.8 21.1 34.2 23.2 8.8 4.6 37.9 15.8 2.5 7.9 3.4 10.1 2.2 5.1 9.1 10.9 4.1 37.2 18.3 1.9 7.6 13.0 19.2 9.9 20.6 11.9 2.8 1.1 6.4 20.0 13.2 8.2 6.3 6.4 4.1 8.6 8.4 3.6 6.5 10.7 14.5 27.8 4.2 1.9 24.1 5.0 40.9 7.3 18.1 10.3 9.4 19.6 0.5 0.0 6.1 0.3 6.2 1.8 18.0 0.0 0.1 0.0 0.0 0.1 0.0 2.9 1.0 0.0 4.2 3.7 1.5 2.4 0.0 6.8 0.2 3.8 0.1 0.0 3.3 0.1 53.1 3.1 2.3 0.5 0.0 4.9 43.1 0.1 0.4 4.8 3.8 0.4 0.1 12.9 2.7 0.3 0.0 2.1 95.6 0.4 5.1 24.4 1.0 3.6 0.0 28.2 0.0 7.4 1.1 1.7 34.1 0.4 5.4 0.0 0.2 2.8 0.1 3.4 13.9 2.8 2.0 0.2 100.1 140.5 21.6 129.7 2.5 37.2 1.0 11.3 66.4 32.3 0.8 8.1 195.4 58.1 159.2 33.0 0.4 43.2 29.8 34.2 4.6 37.9 37.2 18.3 9.9 20.6 13.2 14.5 24.1 19.6 12.2 0.0 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 46.4 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 102.6 4.7 0.0 0.0 0.0 0.0 0.0 0.0 37.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 150.0 0.7 0.0 0.0 0.0 DACT1 "DAPPER, DAPPER1, FRODO, HDPR1, THYEX3" ENSG00000165617 "Dishevelled binding antagonist of beta catenin 1" Q9NYF0 14 58633967-58648321 "Disease related genes, Predicted intracellular proteins" "Neurogenesis, Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 56.0;Late spermatids: 17.9;Peritubular cells: 27.8;Smooth muscle cells: 15.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 17.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-MEL-30: 13.5;SuSa: 17.2;U-138 MG: 31.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003016, HPA074619" Enhanced Supported Nucleoplasm NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA003016: AB_1078623, HPA074619: " "unprognostic (2.47e-2)" "unprognostic (2.72e-2)" "unprognostic (1.79e-2)" "unprognostic (1.22e-1)" "unprognostic (1.03e-2)" "unprognostic (3.55e-2)" "unprognostic (1.37e-1)" "unprognostic (1.17e-2)" "unprognostic (4.79e-2)" "unprognostic (1.93e-1)" "unprognostic (5.42e-2)" "unprognostic (6.54e-2)" "unprognostic (4.16e-2)" "unprognostic (1.64e-2)" "unprognostic (2.54e-1)" "unprognostic (1.37e-3)" "unprognostic (1.89e-3)" 8.6 7.9 5.2 4.1 4.2 1.5 6.5 17.4 3.3 12.0 0.6 6.3 5.9 7.6 5.8 2.9 5.9 24.9 8.0 3.6 2.5 5.5 2.7 9.3 4.1 1.6 3.2 24.4 2.3 8.0 3.8 12.1 2.0 11.8 6.7 2.0 3.5 13.1 2.4 2.7 3.9 8.9 2.0 7.2 6.9 9.8 2.4 3.6 10.7 4.4 2.3 14.0 6.6 3.4 0.0 0.0 4.0 0.1 4.5 5.0 0.1 2.3 2.9 2.4 2.1 0.3 0.2 0.0 0.1 6.9 4.0 3.6 11.5 0.0 1.3 2.7 2.4 0.0 0.1 0.0 8.2 0.0 1.3 5.9 0.3 9.0 0.0 9.0 0.1 0.8 0.0 0.0 1.6 0.0 0.9 0.1 3.8 0.2 0.9 4.9 5.6 0.0 0.0 0.0 0.1 0.0 6.5 0.0 13.5 17.2 0.0 0.4 0.0 31.7 10.8 0.5 8.5 4.4 1.8 0.0 3.4 1.4 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.2 4.2 17.4 3.3 3.6 2.5 1.6 3.2 2.0 2.0 2.4 3.4 1.1 0.0 0.0 0.3 1.0 0.8 1.2 0.0 1.2 0.4 0.3 1.5 3.9 7.2 0.0 1.8 0.0 0.2 0.2 0.3 0.0 1.7 56.0 0.4 9.3 1.4 0.0 0.0 2.7 2.3 0.8 11.7 2.0 0.3 0.0 2.3 4.2 0.0 1.2 0.0 4.0 1.0 0.0 2.9 2.1 17.9 12.2 0.6 1.8 6.5 0.0 4.5 0.0 1.5 0.8 3.1 0.0 27.8 0.6 0.4 0.0 1.0 0.0 0.5 0.0 2.9 15.7 12.6 8.6 0.3 1.3 0.1 0.5 3.6 0.5 0.4 DCHS1 "CDH25, CDHR6, FIB1, FLJ11790, KIAA1773, PCDH16" ENSG00000166341 "Dachsous cadherin-related 1" Q96JQ0 11 6621330-6655809 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 34.8;Endometrial stromal cells: 17.3;Endothelial cells: 29.0;Fibroblasts: 17.0;Granulosa cells: 19.3;Hepatic stellate cells: 61.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 33.5;HUVEC TERT2: 47.1;REH: 23.5;SH-SY5Y: 32.4;TIME: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017970, HPA050246" Approved Approved "Plasma membrane" NA NA 4000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA017970: AB_2669718, HPA050246: AB_2681062" "unprognostic (2.42e-1)" "unprognostic (1.13e-1)" "unprognostic (8.93e-2)" "unprognostic (3.52e-2)" "unprognostic (1.83e-1)" "unprognostic (1.38e-3)" "unprognostic (2.52e-2)" "unprognostic (4.55e-3)" "unprognostic (2.63e-2)" "unprognostic (2.93e-2)" "unprognostic (5.96e-2)" "unprognostic (6.87e-2)" "prognostic unfavorable (9.32e-4)" "unprognostic (5.62e-2)" "unprognostic (2.28e-1)" "unprognostic (1.60e-2)" "unprognostic (1.24e-3)" 9.4 2.5 7.4 8.4 6.8 0.7 9.3 6.1 6.3 19.5 0.9 19.0 4.1 28.9 2.4 5.0 13.2 8.3 9.2 6.6 10.1 4.6 2.0 10.1 4.0 7.6 6.3 11.6 3.3 2.0 3.2 10.1 5.7 9.3 3.4 0.6 3.5 11.5 4.2 3.7 8.3 16.2 4.7 12.9 8.2 3.0 8.7 3.8 4.1 4.6 2.2 14.8 9.3 3.8 0.0 0.1 33.5 0.1 0.0 0.1 0.3 1.2 8.7 5.4 6.0 0.3 0.0 0.1 5.1 9.9 0.4 0.0 2.7 0.1 3.7 0.1 0.9 0.7 0.0 0.0 0.3 0.2 0.0 1.0 0.1 2.5 0.0 0.0 47.1 0.1 0.2 0.0 2.0 0.0 1.2 0.6 5.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 2.4 32.4 0.0 0.3 0.2 3.5 0.0 1.3 20.4 0.1 10.0 0.1 0.0 0.1 0.0 0.1 0.3 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 7.4 6.8 6.1 6.3 6.6 10.1 7.6 6.3 5.7 4.7 8.7 3.8 34.8 0.0 0.5 12.1 0.2 2.9 0.3 0.0 0.0 1.5 1.7 3.0 3.8 4.3 0.0 0.0 0.0 0.2 1.4 0.2 0.0 1.0 3.1 0.8 17.3 29.0 0.0 2.7 2.0 0.4 0.3 17.0 1.1 0.7 0.0 19.3 61.1 0.2 2.2 0.0 7.4 0.7 0.0 4.7 4.2 3.4 1.2 2.4 16.0 4.7 0.2 0.9 0.0 10.1 1.4 0.1 0.1 1.9 0.2 0.3 0.1 0.1 0.0 0.5 0.0 7.4 4.9 4.9 0.6 0.5 1.7 0.3 1.2 4.6 1.1 0.1 DCLK1 "DCAMKL1, DCDC3A, DCLK, KIAA0369" ENSG00000133083 "Doublecortin like kinase 1" O15075 13 35768652-36131382 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.0" "Group enriched" "Detected in many" 6 "Excitatory neurons: 970.6;Inhibitory neurons: 664.8" "Cancer enhanced" "Detected in many" "glioma: 12.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 29.0;ASC TERT1: 27.3;fHDF/TERT166: 23.5;GAMG: 34.8;HAP1: 17.9;HSkMC: 25.5;NTERA-2: 37.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012405, HPA015040, HPA015655" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Cytosol "CAB012405: , HPA015040: AB_2669141, HPA015655: AB_2669265" "unprognostic (2.29e-1)" "unprognostic (2.56e-1)" "unprognostic (7.45e-2)" "unprognostic (1.30e-2)" "unprognostic (1.99e-1)" "unprognostic (2.35e-2)" "unprognostic (1.48e-1)" "unprognostic (3.30e-2)" "unprognostic (1.66e-1)" "unprognostic (1.74e-1)" "unprognostic (7.72e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (4.42e-4)" "unprognostic (1.93e-3)" "unprognostic (1.29e-1)" "unprognostic (1.34e-1)" "unprognostic (1.14e-4)" 15.5 2.5 22.0 4.0 27.5 0.0 14.2 10.2 45.3 11.8 0.0 4.2 1.1 6.0 4.1 5.4 4.6 7.2 5.5 37.1 37.8 2.8 0.1 2.4 4.2 17.9 13.2 6.1 1.2 1.1 13.7 0.1 53.0 4.1 3.8 17.3 3.4 4.0 2.1 8.4 4.1 19.1 15.7 4.5 3.6 1.3 17.5 1.6 2.8 4.6 2.2 4.3 5.9 18.7 0.0 0.4 6.8 0.0 29.0 27.3 0.0 0.2 0.4 0.2 0.2 0.0 0.1 0.0 0.0 23.5 34.8 0.0 17.9 0.3 0.0 0.0 1.0 0.0 0.8 0.0 1.1 0.0 0.0 25.5 13.0 0.6 0.4 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 37.1 0.0 0.4 0.0 2.0 0.0 1.0 0.0 7.3 4.4 0.0 0.0 2.2 10.4 0.0 0.0 0.0 0.1 6.1 7.6 1.3 0.1 0.0 0.0 2.4 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.0 27.5 10.2 45.3 37.1 37.8 17.9 13.2 53.0 15.7 17.5 18.7 8.0 9.6 0.6 132.2 0.1 15.2 1.3 1.8 0.0 9.4 7.8 7.0 5.8 0.0 7.9 3.7 4.2 0.0 0.0 0.0 0.0 0.1 1.5 0.7 1.7 3.8 0.0 0.0 970.6 0.0 0.0 82.6 0.5 0.3 0.0 75.5 0.4 0.0 0.1 10.1 664.8 0.0 4.1 0.3 14.7 1.6 20.8 0.7 14.2 44.0 0.0 73.8 0.0 31.2 19.1 0.2 0.0 4.1 0.3 0.6 0.0 0.6 3.1 4.2 6.6 10.8 22.0 1.3 1.4 1.0 9.7 0.0 0.8 30.1 0.0 1.7 DSEL "C18orf4, DE-epi2, FLJ11477, NCAG1" ENSG00000171451 "Dermatan sulfate epimerase like" Q8IZU8 18 67506587-67516720 "Predicted membrane proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 86.4;Extravillous trophoblasts: 72.5;Oligodendrocyte precursor cells: 112.6;Oligodendrocytes: 104.2;Theca cells: 83.9" "Cancer enhanced" "Detected in many" "glioma: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 70.7;BJ hTERT+: 43.0;fHDF/TERT166: 38.9;LHCN-M2: 92.1;U-138 MG: 95.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060942 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Plasma membrane" Nucleoplasm "HPA060942: AB_2684392" "unprognostic (2.49e-1)" "unprognostic (5.00e-1)" "unprognostic (1.67e-1)" "unprognostic (1.19e-5)" "unprognostic (1.56e-1)" "unprognostic (2.71e-1)" "unprognostic (2.40e-3)" "unprognostic (7.11e-2)" "unprognostic (4.91e-1)" "unprognostic (2.83e-1)" "unprognostic (2.19e-2)" "unprognostic (2.47e-1)" "unprognostic (7.95e-3)" "unprognostic (3.25e-2)" "unprognostic (1.24e-1)" "unprognostic (9.70e-3)" "unprognostic (1.16e-4)" 4.0 1.3 5.1 1.3 8.5 0.3 2.6 7.3 4.7 5.1 0.7 2.2 0.6 2.6 1.6 1.1 3.3 4.0 2.2 5.1 6.4 4.3 3.5 2.7 0.5 9.5 7.4 3.6 1.5 3.2 0.3 6.1 8.8 2.0 1.3 0.8 0.8 2.1 0.7 1.2 1.1 3.6 5.9 2.0 1.2 1.3 7.0 0.8 1.0 1.8 0.3 1.7 1.4 11.7 0.0 0.3 8.7 0.1 16.5 24.3 0.9 70.7 43.0 19.2 8.3 0.1 0.2 0.0 0.1 38.9 4.7 0.4 1.7 3.5 18.5 0.0 0.1 0.0 8.5 0.1 14.6 0.0 0.1 25.3 5.1 11.7 26.0 6.8 3.8 0.0 0.0 1.1 92.1 0.0 0.0 0.0 1.3 0.0 3.7 0.8 19.3 0.1 8.7 0.1 3.1 4.0 4.8 0.2 0.0 3.7 0.1 0.0 6.2 95.6 2.4 6.2 8.6 0.3 0.0 0.0 20.0 0.0 8.1 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 5.1 8.5 7.3 4.7 5.1 6.4 9.5 7.4 8.8 5.9 7.0 11.7 15.9 6.4 16.2 3.3 2.6 11.6 9.9 8.6 19.4 10.1 14.5 12.3 13.3 47.1 5.2 11.0 4.2 2.8 1.4 1.0 0.0 9.7 1.8 3.9 86.4 10.9 6.6 0.0 10.3 2.3 72.5 44.3 8.2 4.2 4.5 9.5 13.2 15.6 2.6 3.3 25.5 1.1 0.0 2.2 9.3 1.7 24.5 3.5 7.2 2.8 0.0 12.6 1.0 112.6 104.2 6.6 0.1 36.9 0.3 8.5 0.4 26.4 1.3 4.2 13.1 43.3 20.9 31.6 21.9 7.1 13.2 8.9 4.9 83.9 0.7 5.2 DTX1 "hDx-1, RNF140" ENSG00000135144 "Deltex E3 ubiquitin ligase 1" Q86Y01 12 113056709-113098028 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.1;lymphoid tissue: 11.8" "Group enriched" "Detected in many" 6 "Astrocytes: 48.3;Horizontal cells: 171.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "Daudi: 109.1;REH: 45.1;U-698: 110.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051249, HPA055275" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA051249: , HPA055275: AB_2682769" "unprognostic (2.13e-3)" "unprognostic (3.20e-3)" "unprognostic (4.24e-4)" "unprognostic (2.01e-1)" "unprognostic (7.48e-3)" "unprognostic (1.59e-3)" "unprognostic (2.49e-3)" "unprognostic (1.81e-1)" "unprognostic (9.55e-2)" "unprognostic (6.87e-2)" "unprognostic (2.19e-1)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.02e-5)" "unprognostic (2.41e-2)" "unprognostic (4.70e-1)" "unprognostic (1.63e-1)" "unprognostic (4.78e-3)" 9.0 1.7 6.5 5.7 6.8 2.7 6.4 3.2 5.9 2.4 0.2 0.8 1.3 1.5 0.3 0.9 1.8 0.8 1.2 5.2 11.1 3.5 8.9 0.8 11.1 5.2 8.8 0.4 1.6 0.0 3.3 0.3 5.1 0.8 0.1 2.9 2.6 0.3 0.5 1.0 3.5 0.3 3.7 11.8 0.9 1.9 10.5 0.5 2.2 0.1 6.0 0.5 0.6 2.4 0.2 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 109.1 0.8 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.6 0.0 0.0 0.3 4.6 0.0 2.0 0.2 0.0 45.1 0.2 2.6 0.0 0.0 2.7 7.1 0.4 0.4 2.5 0.0 0.1 0.2 1.2 0.0 4.0 0.0 0.1 0.5 0.2 110.7 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.5 6.8 3.2 5.9 5.2 11.1 5.2 8.8 5.1 3.7 10.5 2.4 0.7 0.0 0.0 48.3 8.8 1.0 0.0 0.0 0.0 4.7 0.2 0.6 0.7 0.0 0.0 1.8 8.4 0.0 0.3 0.1 7.9 2.5 0.7 0.7 17.5 1.7 0.0 0.0 10.6 0.0 0.0 4.5 0.5 0.4 7.0 0.0 0.4 12.4 0.8 171.6 13.8 0.1 0.0 0.3 0.6 1.7 7.8 0.2 3.6 2.8 0.0 11.4 2.1 13.0 1.0 0.2 0.1 7.5 2.5 0.0 0.0 0.2 0.0 2.8 0.0 0.4 1.3 0.8 2.4 0.0 0.4 0.0 2.2 0.8 0.0 0.0 DTX4 "KIAA0937, RNF155" ENSG00000110042 "Deltex E3 ubiquitin ligase 4" Q9Y2E6 11 59171430-59208588 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 33.6;Oligodendrocytes: 33.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 63.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 62.8;CACO-2: 34.5;CAPAN-2: 37.7;OE19: 35.4;RT4: 95.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056760, HPA059294" Approved Approved Vesicles NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA056760: AB_2683228, HPA059294: AB_2683969" "unprognostic (3.23e-2)" "unprognostic (1.57e-1)" "unprognostic (1.10e-2)" "unprognostic (4.98e-2)" "unprognostic (4.97e-2)" "unprognostic (5.03e-1)" "unprognostic (2.92e-1)" "unprognostic (1.06e-1)" "unprognostic (3.75e-1)" "unprognostic (1.14e-1)" "unprognostic (5.69e-2)" "unprognostic (3.04e-1)" "prognostic unfavorable (8.94e-4)" "unprognostic (5.51e-2)" "unprognostic (2.51e-1)" "prognostic favorable (5.81e-4)" "unprognostic (2.57e-3)" 10.4 1.9 13.9 5.5 21.2 9.3 9.5 21.4 20.0 8.0 8.2 17.5 16.4 3.8 1.9 4.7 5.8 4.9 3.2 13.2 21.2 8.5 32.5 18.1 5.3 30.2 22.4 15.0 7.9 1.0 4.1 14.8 27.0 7.5 17.2 10.4 21.7 3.1 1.4 3.9 14.4 2.5 33.5 6.7 11.6 1.7 25.6 1.5 10.2 1.7 6.5 15.0 3.9 50.5 4.8 5.7 30.5 0.6 8.5 0.5 62.8 0.4 2.7 0.3 0.4 34.5 37.7 11.6 2.1 0.7 1.2 16.5 9.5 11.8 0.1 0.8 0.5 0.1 6.6 11.2 2.4 0.9 2.3 1.4 19.3 0.1 0.5 2.1 0.0 2.1 0.1 1.1 1.4 2.7 0.5 0.1 16.1 35.4 1.5 4.1 27.1 1.3 2.6 95.2 0.0 0.1 24.3 6.4 0.8 7.7 4.9 0.5 0.3 0.1 4.9 0.1 0.0 0.4 0.1 1.1 0.2 2.8 2.6 0.7 0.4 0.4 0.0 0.4 0.0 1.0 0.0 0.0 0.6 1.3 0.0 0.0 1.5 0.0 0.2 2.8 0.0 0.1 13.9 21.2 21.4 20.0 13.2 21.2 30.2 22.4 27.0 33.5 25.6 50.5 8.9 19.2 16.8 9.4 3.1 1.7 3.2 7.9 2.2 2.0 2.9 3.9 1.4 28.6 21.8 7.3 0.0 15.0 6.9 33.6 0.0 10.2 0.4 1.5 8.1 3.6 4.9 0.0 12.0 4.9 19.2 7.2 12.2 3.0 1.3 4.9 5.7 23.1 3.7 0.0 8.4 10.5 2.0 2.5 2.5 0.4 4.1 2.7 5.4 3.7 0.9 30.3 0.0 7.5 33.9 10.8 16.3 3.4 0.0 3.1 19.8 9.1 14.9 2.0 0.0 22.1 3.6 0.4 1.7 1.8 1.3 5.5 1.2 5.9 18.5 22.5 DUOXA1 "FLJ32334, mol, NIP, NUMBIP" ENSG00000140254 "Dual oxidase maturation factor 1" Q1HG43 15 45117367-45129938 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 189.0;skin 1: 91.6;thyroid gland: 111.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 60.9;Alveolar cells type 2: 118.0;Club cells: 35.5;Glandular and luminal cells: 47.7;Respiratory ciliated cells: 36.9;Squamous epithelial cells: 53.6;Urothelial cells: 44.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 30.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HaCaT: 103.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA041578 Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 11: Alveolar cells - Smell perception" "HPA041578: AB_10795691" "unprognostic (1.28e-1)" "unprognostic (1.32e-3)" "unprognostic (1.88e-1)" "unprognostic (2.66e-2)" "unprognostic (2.71e-1)" "unprognostic (6.87e-3)" "unprognostic (1.03e-1)" "unprognostic (4.45e-2)" "unprognostic (6.69e-2)" "unprognostic (3.68e-2)" "unprognostic (5.82e-2)" "unprognostic (1.86e-1)" "unprognostic (2.17e-5)" "unprognostic (8.11e-2)" "unprognostic (1.12e-2)" "unprognostic (4.69e-2)" "unprognostic (5.36e-2)" 1.1 5.0 0.2 1.3 0.5 0.1 4.0 0.7 1.1 32.1 0.0 0.9 0.8 4.6 49.3 189.0 5.7 4.3 2.1 0.5 0.3 0.8 0.3 64.3 0.1 0.6 0.1 1.1 0.4 5.0 0.7 0.8 0.8 21.6 0.5 0.1 27.5 12.0 0.5 91.6 0.8 0.2 0.1 0.1 43.6 0.2 0.7 0.7 111.1 0.0 17.9 23.3 77.4 2.9 10.6 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 103.9 0.0 0.2 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 14.5 0.0 0.3 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.7 1.1 0.5 0.3 0.6 0.1 0.8 0.1 0.7 2.9 0.0 60.9 118.0 1.0 0.0 9.4 18.8 26.9 18.2 0.6 1.4 1.7 0.5 0.0 35.5 0.0 2.1 2.4 0.0 3.3 0.0 2.0 0.1 28.7 4.0 0.8 3.0 0.0 0.7 3.1 0.1 1.6 8.6 47.7 1.3 0.3 0.0 0.0 0.3 0.0 0.4 0.1 4.1 0.0 1.2 0.0 0.3 0.8 0.0 0.0 0.6 0.1 0.0 0.5 1.8 1.9 3.3 0.0 0.0 13.4 0.0 0.0 36.9 0.1 0.0 0.7 1.1 0.0 0.9 53.6 21.9 3.0 0.6 0.1 0.4 44.2 DZIP1 "DZIP, KIAA0996" ENSG00000134874 "DAZ interacting zinc finger protein 1" Q86YF9 13 95578202-95644706 "Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 384.1;Late spermatids: 774.5;Spermatocytes: 222.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054891, HPA057272" Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 43: Testis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Centrosome" "HPA054891: AB_2682631, HPA057272: AB_2683390" "unprognostic (6.74e-3)" "unprognostic (7.65e-2)" "unprognostic (1.94e-1)" "unprognostic (4.64e-3)" "unprognostic (4.82e-2)" "unprognostic (5.52e-3)" "unprognostic (6.34e-2)" "unprognostic (2.49e-1)" "unprognostic (3.34e-2)" "unprognostic (8.63e-2)" "unprognostic (1.17e-2)" "unprognostic (1.67e-1)" "unprognostic (1.36e-2)" "unprognostic (2.41e-3)" "unprognostic (1.48e-1)" "unprognostic (3.64e-2)" "unprognostic (3.89e-3)" 5.0 3.4 8.6 2.5 8.5 0.1 4.4 6.9 9.4 12.4 5.7 10.7 1.0 12.6 7.2 3.2 12.4 5.1 4.3 7.7 8.7 11.4 1.1 4.6 2.2 7.0 8.1 16.3 9.9 0.4 10.3 2.5 6.1 6.4 1.8 4.0 2.3 6.2 1.3 1.6 4.0 6.1 5.6 1.5 4.7 14.8 11.5 0.8 2.4 2.1 1.7 7.9 7.1 7.1 1.1 4.2 17.5 15.5 14.5 16.2 3.6 11.0 13.2 12.7 15.2 0.2 0.0 0.0 2.5 9.4 5.5 0.0 11.7 3.8 14.8 1.1 9.6 15.6 4.4 11.0 9.2 0.1 0.0 11.7 0.4 4.2 5.8 23.1 9.1 1.1 0.0 0.1 11.4 0.0 0.0 0.0 8.6 0.0 0.4 0.0 10.1 0.0 15.4 1.8 4.2 9.9 8.3 0.0 0.6 22.4 0.0 7.3 1.3 12.3 5.3 1.8 8.8 0.0 0.0 0.0 3.5 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.6 8.5 6.9 9.4 7.7 8.7 7.0 8.1 6.1 5.6 11.5 7.1 2.4 0.0 0.0 63.6 0.0 0.6 1.1 3.1 4.6 18.7 0.6 3.4 3.5 2.8 3.9 1.8 4.2 4.5 0.0 0.0 7.9 20.8 384.1 37.2 34.1 2.5 0.0 0.0 86.8 0.2 2.6 19.0 0.5 2.7 0.0 3.1 2.9 0.4 0.7 6.7 95.7 0.0 4.1 0.3 1.5 774.5 38.8 1.2 3.6 19.7 2.0 8.3 0.0 106.6 5.1 0.6 0.0 43.6 0.0 0.8 0.0 24.4 19.4 1.5 19.7 18.2 15.8 222.8 12.6 1.2 1.0 1.8 0.5 20.8 0.0 0.3 EBF2 "COE2, FLJ11500" ENSG00000221818 "EBF transcription factor 2" Q9HAK2 8 25841725-26045413 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 17.8" "Cell type enhanced" "Detected in some" "Adipocytes: 11.9;Fibroblasts: 23.2;Microglial cells: 13.1;Sertoli cells: 39.5;Smooth muscle cells: 53.4" "Cancer enhanced" "Detected in many" "renal cancer: 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 22.7;ASC TERT1: 45.7;HSkMC: 46.9;hTEC/SVTERT24-B: 26.7;U-138 MG: 17.1;U-2197: 22.7;U-87 MG: 19.1" "Group enriched" "Detected in many" 4 "basal ganglia: 5.7;cerebellum: 3.1;hypothalamus: 2.0;midbrain: 4.4;pons and medulla: 2.8" "Region enriched" "Detected in many" 5 "spinal cord: 8.7" "HPA003954, HPA055101" Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "HPA003954: , HPA055101: " "unprognostic (3.70e-1)" "unprognostic (3.88e-3)" "unprognostic (2.69e-2)" "unprognostic (2.47e-3)" "unprognostic (1.03e-1)" "unprognostic (6.10e-2)" "unprognostic (5.92e-2)" "unprognostic (6.75e-2)" "unprognostic (1.11e-2)" "unprognostic (6.13e-3)" "unprognostic (1.58e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.51e-6)" "unprognostic (7.41e-4)" "unprognostic (2.28e-1)" "unprognostic (3.80e-2)" "unprognostic (1.82e-2)" 17.8 0.7 0.2 0.9 0.5 0.0 8.0 0.2 0.1 0.7 0.1 1.4 0.0 0.8 1.9 0.8 4.0 2.6 9.8 0.0 0.7 0.5 0.0 0.6 0.6 1.3 3.1 1.0 0.8 2.2 0.4 0.5 2.7 0.5 0.4 0.2 1.4 0.4 4.7 1.5 0.7 1.7 3.8 0.0 0.8 1.1 0.9 1.4 6.2 9.6 0.2 1.9 1.2 0.3 0.0 0.0 0.8 0.0 22.7 45.7 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 46.9 0.0 26.7 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 17.1 0.2 22.7 0.0 0.0 0.0 0.0 19.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.2 0.1 0.0 0.7 1.3 3.1 2.7 3.8 0.9 0.3 11.9 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.6 0.1 0.2 0.3 5.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.1 5.6 0.0 0.0 0.5 0.0 0.0 23.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.4 3.2 5.9 0.6 0.0 13.1 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.2 39.5 2.6 53.4 1.0 0.2 0.4 0.3 0.0 0.2 0.1 0.0 0.1 EBF4 "COE4, KIAA1442, O/E-4, RP5-860F19.3" ENSG00000088881 "EBF family member 4" Q9BQW3 20 2692874-2760108 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 18.9;Cholangiocytes: 21.5;Endometrial stromal cells: 18.6;Oligodendrocyte precursor cells: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 7.9;HEK 293: 8.4;SH-SY5Y: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "unprognostic (9.95e-2)" "unprognostic (1.27e-1)" "prognostic unfavorable (6.59e-4)" "unprognostic (1.22e-1)" "unprognostic (4.14e-2)" "unprognostic (9.57e-2)" "unprognostic (1.00e-1)" "unprognostic (1.60e-1)" "unprognostic (7.79e-3)" "unprognostic (3.82e-1)" "prognostic favorable (2.47e-5)" "unprognostic (2.68e-2)" "unprognostic (5.58e-3)" "unprognostic (1.87e-3)" "unprognostic (2.91e-1)" "unprognostic (1.17e-2)" "unprognostic (2.87e-3)" 2.6 3.5 12.1 2.7 13.5 0.3 2.7 9.1 15.0 5.0 3.0 3.2 2.8 19.0 2.2 4.1 6.7 5.7 2.9 12.9 11.1 2.6 1.1 3.6 2.3 13.4 11.4 13.7 3.8 14.4 2.9 5.7 9.9 12.4 1.9 3.3 5.6 11.1 1.1 2.8 3.8 12.1 10.6 2.2 3.9 1.2 13.1 0.6 18.0 1.5 1.8 3.0 2.0 17.4 0.0 0.7 4.4 4.4 0.1 1.1 0.9 1.2 3.2 2.2 1.1 0.6 0.4 0.0 2.5 0.5 7.9 0.2 1.5 0.2 1.3 6.2 8.4 0.0 0.0 0.2 2.8 0.0 0.0 0.1 1.0 1.0 0.0 0.8 0.3 1.9 0.0 0.0 0.0 0.4 0.1 6.9 0.6 0.0 0.2 6.4 1.2 0.5 0.0 2.7 3.3 21.2 1.2 0.1 1.9 4.2 2.4 0.3 1.7 0.3 1.0 0.2 3.8 1.4 0.2 1.5 0.0 0.9 3.2 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 12.1 13.5 9.1 15.0 12.9 11.1 13.4 11.4 9.9 10.6 13.1 17.4 4.1 0.0 1.1 18.9 0.3 3.4 15.6 3.0 6.8 7.7 18.1 11.0 2.2 21.5 5.5 1.8 0.0 0.2 5.1 0.2 0.0 2.0 0.4 1.2 18.6 3.2 0.0 0.0 3.1 0.4 0.1 5.1 1.1 1.1 0.0 1.9 6.4 5.7 0.3 5.0 12.2 0.2 4.1 0.8 1.4 0.8 3.4 0.3 1.8 10.3 0.0 5.5 2.1 52.3 17.9 0.3 1.7 7.2 0.4 11.3 0.0 0.2 4.9 2.3 6.6 3.3 5.1 0.6 1.4 0.6 1.0 0.3 0.7 0.1 0.4 9.3 ECM2 ENSG00000106823 "Extracellular matrix protein 2" O94769 9 92493554-92536655 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 122.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 73.3;Hepatocytes: 49.3;Leydig cells: 122.1;Peritubular cells: 69.6;Skeletal myocytes: 43.6;Smooth muscle cells: 50.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "ASC diff: 19.1;ASC TERT1: 34.5;HSkMC: 36.8;hTCEpi: 42.8;hTERT-HME1: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035347, HPA035348" Approved Approved "Mitotic spindle,Centrosome,Cytosol" "Secreted to extracellular matrix" Yes NA 10000000 "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Centrosome, Cytosol" "Mitotic spindle" "HPA035347: AB_10669856, HPA035348: " "unprognostic (2.48e-1)" "unprognostic (2.11e-1)" "unprognostic (2.27e-2)" "unprognostic (2.20e-2)" "unprognostic (5.35e-2)" "unprognostic (2.30e-1)" "prognostic favorable (4.50e-5)" "unprognostic (6.14e-2)" "unprognostic (2.14e-2)" "unprognostic (1.79e-1)" "unprognostic (1.66e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (4.09e-6)" "unprognostic (1.12e-3)" "unprognostic (2.39e-2)" "unprognostic (3.80e-2)" "unprognostic (6.63e-3)" 122.1 14.3 5.0 2.1 5.0 0.6 34.8 6.0 4.9 43.5 8.1 6.8 9.0 40.8 23.2 9.0 30.0 31.7 31.5 4.5 11.6 28.4 81.5 22.5 8.3 5.2 10.3 91.6 6.3 9.1 6.1 3.5 5.8 21.2 7.4 0.3 7.2 22.2 7.4 9.7 14.8 27.8 4.4 0.9 4.3 16.8 8.0 5.0 11.4 24.6 7.8 13.3 11.1 12.0 0.7 0.1 0.4 0.0 19.1 34.5 1.3 0.8 1.1 0.1 0.5 0.6 0.0 0.0 0.1 1.9 0.3 0.5 0.9 0.8 0.1 4.4 0.0 0.0 0.0 0.0 3.3 0.2 0.0 36.8 42.8 0.9 11.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.7 0.5 0.1 0.0 0.1 0.0 2.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 5.0 6.0 4.9 4.5 11.6 5.2 10.3 5.8 4.4 8.0 12.0 12.9 0.0 2.3 5.5 0.3 11.5 0.1 0.6 0.6 3.0 0.3 1.3 5.5 1.5 2.0 0.0 2.1 0.1 0.3 0.2 0.0 0.1 5.1 0.6 18.6 5.2 0.0 0.8 3.4 0.0 16.2 73.3 0.5 0.5 0.0 18.2 2.2 49.3 0.4 0.0 2.8 0.4 0.0 1.3 15.4 8.9 122.1 1.1 5.4 17.8 0.1 0.1 0.0 0.5 2.9 0.0 0.2 69.6 1.4 0.1 11.1 9.2 3.3 2.5 26.3 43.6 50.2 0.9 0.6 0.9 9.1 0.8 0.9 13.5 0.6 0.2 EEF1AKMT3 "DKFZP586D0919, FAM119B, METTL21B" ENSG00000123427 "EEF1A lysine methyltransferase 3" Q96AZ1 12 57771492-57782541 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 14.9;Breast myoepithelial cells: 7.6;Exocrine glandular cells: 12.7;monocytes: 8.8;Proximal tubular cells: 16.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in all" 7 "RH-30: 152.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA043020, HPA045492" Uncertain Approved "Nucleoplasm,Mitotic chromosome,Centrosome" Yes NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 7: Non-specific - Mitochondria" Centrosome "Nucleoplasm, Mitotic chromosome" "HPA043020: AB_2678274, HPA045492: " "unprognostic (2.00e-1)" "unprognostic (6.52e-2)" "unprognostic (7.96e-2)" "unprognostic (1.60e-1)" "unprognostic (1.53e-1)" "unprognostic (2.01e-1)" "unprognostic (1.55e-3)" "unprognostic (1.06e-1)" "unprognostic (7.34e-3)" "unprognostic (7.52e-3)" "unprognostic (1.66e-1)" "unprognostic (2.32e-1)" "unprognostic (1.54e-3)" "unprognostic (5.77e-2)" "unprognostic (1.33e-1)" "unprognostic (1.34e-2)" "unprognostic (1.23e-1)" 7.5 6.2 2.5 3.6 2.3 2.6 9.2 4.1 2.7 10.5 2.6 5.6 3.9 9.3 9.6 5.6 8.4 5.4 3.7 2.4 1.8 11.6 6.5 5.3 3.6 2.6 2.4 11.4 21.7 6.4 3.7 4.6 2.7 8.2 4.6 3.7 19.4 8.7 2.9 7.3 3.8 7.6 2.1 4.0 7.2 4.2 2.4 1.9 10.1 3.1 3.1 6.3 7.3 3.1 5.4 11.0 4.6 5.9 12.8 12.0 4.0 5.8 10.9 8.9 9.0 5.6 9.5 3.1 7.4 7.6 7.2 5.2 3.7 3.3 9.3 4.0 5.6 14.9 6.6 9.2 11.3 3.7 6.6 12.6 8.7 9.3 9.8 15.2 9.7 13.2 8.9 22.6 5.4 3.8 4.7 11.0 3.4 4.3 8.0 8.5 152.1 10.0 6.0 5.3 4.4 6.0 10.0 7.5 6.2 4.1 11.9 10.0 9.5 13.7 7.7 5.8 6.4 5.7 2.3 3.8 11.3 15.4 10.0 0.4 3.0 0.1 1.8 1.1 7.8 0.5 3.5 2.2 3.1 0.4 1.7 1.4 0.7 1.5 4.6 1.5 2.2 2.3 2.5 2.3 4.1 2.7 2.4 1.8 2.6 2.4 2.7 2.1 2.4 3.1 3.9 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 14.9 7.6 0.0 0.0 1.8 1.8 0.0 3.4 1.3 0.0 5.9 5.5 0.0 2.0 6.0 1.9 0.0 0.0 0.0 12.7 4.9 3.4 0.0 2.5 2.5 5.4 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 8.8 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.1 0.0 0.0 16.4 1.5 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 1.6 0.5 4.7 0.0 0.0 EFS "CASS3, EFS1, EFS2, HEFS, SIN" ENSG00000100842 "Embryonal Fyn-associated substrate" O43281 14 23356403-23365752 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 48.9;Squamous epithelial cells: 22.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 73.2;AN3-CA: 39.5;BEWO: 57.7;SH-SY5Y: 66.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001581, HPA001790" Approved Uncertain Nucleoplasm,Cytosol No NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm Cytosol "HPA001581: AB_2666367, HPA001790: " "unprognostic (9.58e-3)" "unprognostic (1.10e-2)" "unprognostic (3.68e-2)" "unprognostic (1.78e-1)" "unprognostic (6.05e-2)" "unprognostic (5.76e-2)" "unprognostic (3.00e-1)" "unprognostic (3.85e-2)" "unprognostic (7.36e-2)" "unprognostic (2.15e-1)" "unprognostic (2.75e-1)" "unprognostic (1.00e-2)" "prognostic unfavorable (4.09e-5)" "unprognostic (3.44e-3)" "unprognostic (1.73e-1)" "unprognostic (2.16e-1)" "unprognostic (1.29e-1)" 19.3 12.6 39.7 5.5 59.6 0.0 22.7 51.7 45.6 47.3 28.0 24.4 3.1 29.2 9.9 44.1 28.6 8.7 15.0 35.6 39.3 10.0 1.8 12.1 3.6 63.0 57.6 41.9 2.2 22.2 8.4 10.4 54.8 36.8 3.3 10.6 26.2 22.5 3.6 59.0 9.6 12.5 44.8 7.6 11.9 5.4 49.9 3.2 17.5 5.1 4.8 25.3 42.9 76.0 4.7 0.0 73.2 39.5 17.1 20.0 57.7 5.3 11.3 2.0 0.9 0.0 0.0 0.0 0.0 30.3 0.3 27.5 0.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 11.6 18.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 28.1 0.0 0.0 0.0 22.6 0.1 0.0 24.1 7.8 66.5 15.1 2.6 0.0 8.7 17.6 0.0 0.0 7.6 0.0 19.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.7 59.6 51.7 45.6 35.6 39.3 63.0 57.6 54.8 44.8 49.9 76.0 2.0 0.0 6.7 17.0 0.0 11.6 11.6 5.6 9.6 5.0 20.3 16.3 0.7 0.0 4.1 0.0 6.2 9.3 0.2 0.0 1.9 0.1 0.9 0.6 18.9 1.8 0.0 0.0 0.2 0.0 14.7 15.7 0.0 0.7 0.0 4.4 1.8 0.0 1.6 0.0 0.3 0.0 0.0 0.0 3.7 0.8 20.2 0.4 7.2 1.9 0.0 9.0 0.0 22.1 48.9 0.0 0.0 13.9 0.1 7.6 0.0 0.3 1.1 9.3 6.6 12.6 8.9 2.2 0.5 22.7 13.4 18.1 0.5 0.3 0.0 7.0 EGFR "ERBB, ERBB1" ENSG00000146648 "Epidermal growth factor receptor" P00533 7 55019017-55211628 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Host-virus interaction" "Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 287.9;Skeletal myocytes: 251.2;Syncytiotrophoblasts: 376.8" "Cancer enhanced" "Detected in all" "glioma: 136.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 13 "A-431: 5282.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000035, HPA001200, HPA018530, CAB068186, CAB073534" Enhanced Enhanced "Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 4740000 88000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cell Junctions" "CAB000035: , CAB068186: AB_2665679, CAB073534: , HPA001200: AB_1078723, HPA018530: AB_1848044" "unprognostic (2.62e-2)" "unprognostic (9.56e-3)" "unprognostic (1.59e-1)" "unprognostic (7.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.27e-2)" "unprognostic (6.11e-2)" "unprognostic (4.88e-2)" "unprognostic (2.85e-2)" "unprognostic (3.30e-3)" "unprognostic (1.78e-3)" "unprognostic (1.04e-1)" "unprognostic (1.93e-3)" "unprognostic (6.98e-3)" "unprognostic (1.72e-1)" "unprognostic (6.62e-2)" "prognostic unfavorable (2.04e-5)" 27.9 11.4 12.6 4.0 18.3 0.0 20.0 16.6 9.7 20.4 10.5 12.2 5.7 11.4 10.3 23.5 13.9 9.0 7.1 6.3 10.3 11.6 35.3 14.9 2.5 10.4 19.0 15.1 15.8 3.5 2.9 67.9 8.9 16.2 10.7 10.2 22.1 15.0 10.9 51.0 9.5 9.3 7.5 5.1 11.1 4.2 22.6 12.8 20.6 20.6 8.3 14.7 24.1 6.3 5282.1 61.9 16.5 22.4 102.7 63.5 16.7 47.9 68.7 30.8 23.8 11.5 54.2 2.7 11.4 43.8 130.7 197.1 0.4 230.2 37.1 2.2 3.6 0.1 27.3 3.4 27.0 0.0 0.2 31.2 205.4 74.1 409.9 45.5 4.0 0.0 0.0 0.5 68.0 3.0 0.1 0.1 5.1 21.2 30.4 0.1 9.1 0.2 38.1 52.6 0.8 20.0 42.7 50.6 9.3 16.8 4.9 12.0 15.6 27.1 7.2 215.7 45.8 0.1 4.8 3.1 37.9 1.6 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 18.3 16.6 9.7 6.3 10.3 10.4 19.0 8.9 7.5 22.6 6.3 16.4 96.1 49.9 147.6 1.2 85.8 77.1 101.5 116.1 3.5 12.1 30.4 11.1 47.1 50.6 22.0 6.2 287.9 0.0 45.9 0.0 32.9 4.9 25.9 57.2 12.5 4.2 8.0 1.2 24.3 37.1 91.6 22.4 39.8 0.0 50.6 6.8 79.5 28.3 0.0 107.5 21.6 48.8 7.7 11.6 5.8 128.3 1.9 17.8 40.3 1.6 90.0 0.0 63.3 1.4 54.8 19.9 133.5 0.0 75.4 14.1 13.4 21.7 3.8 78.9 251.2 34.7 2.4 2.5 73.3 89.9 376.8 2.2 41.9 24.9 55.8 EGR2 KROX20 ENSG00000122877 "Early growth response 2" P11161 10 62811996-62919900 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Charcot-Marie-Tooth disease, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 59.9;thyroid gland: 136.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 55.5;Breast myoepithelial cells: 68.1;Enteroendocrine cells: 73.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 19.7" "Group enriched" "Detected in many" 5 "cerebral cortex: 10.2;hippocampal formation: 5.2" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.5;non-classical monocyte: 2.3" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 5 "U-87 MG: 22.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA031165 Supported Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA031165: AB_2673768" "prognostic favorable (7.30e-5)" "unprognostic (1.86e-3)" "unprognostic (1.45e-2)" "unprognostic (8.72e-2)" "unprognostic (2.92e-2)" "unprognostic (1.29e-1)" "unprognostic (2.70e-1)" "unprognostic (1.75e-1)" "unprognostic (9.79e-2)" "unprognostic (1.15e-1)" "unprognostic (1.18e-1)" "unprognostic (1.27e-1)" "unprognostic (2.47e-3)" "unprognostic (6.54e-2)" "unprognostic (1.74e-2)" "unprognostic (3.46e-1)" "unprognostic (1.11e-3)" 13.7 10.6 0.4 9.8 1.2 8.2 8.6 1.3 10.2 18.5 2.0 3.3 1.9 6.0 59.9 8.8 4.5 31.9 14.9 5.2 0.2 7.9 5.4 15.2 14.4 0.3 0.3 9.4 4.2 7.0 8.7 3.0 0.7 17.5 3.7 1.4 2.9 1.9 0.9 14.2 4.6 16.8 0.1 4.5 2.3 4.1 0.6 26.4 136.4 9.1 7.1 15.7 1.7 1.5 0.0 0.2 2.5 1.0 1.8 2.4 0.4 0.5 0.2 0.6 0.8 0.0 0.3 0.6 0.0 0.6 0.7 0.3 0.2 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.6 3.8 0.3 0.6 1.3 0.2 0.8 0.1 0.3 0.2 0.8 0.1 1.2 0.0 1.8 0.2 0.1 1.1 0.1 0.3 0.4 0.0 0.2 0.1 0.3 0.2 0.5 4.2 0.5 0.0 0.5 0.1 0.5 0.4 0.2 0.3 1.3 0.7 0.3 22.5 0.5 0.4 0.0 0.5 0.2 0.1 2.5 0.0 0.4 0.0 0.1 0.5 0.4 0.0 0.1 0.7 0.2 2.3 0.0 0.0 0.4 0.4 1.2 1.3 10.2 5.2 0.2 0.3 0.3 0.7 0.1 0.6 1.5 15.9 0.0 12.6 0.0 14.0 21.3 30.1 36.0 33.0 1.4 55.5 68.1 7.8 0.0 9.4 0.0 0.0 1.1 9.9 9.5 0.0 1.4 8.9 13.9 14.0 16.7 73.1 0.0 1.7 0.6 1.6 30.4 13.3 26.1 20.8 2.3 5.3 2.4 25.2 0.0 0.5 29.4 14.2 28.1 39.5 4.3 1.8 40.5 8.8 0.0 0.8 4.1 0.0 0.0 0.1 1.0 4.4 7.2 6.4 5.5 7.7 0.0 7.1 0.7 6.6 20.7 12.0 0.1 2.0 14.8 12.5 1.1 13.6 5.1 25.8 3.1 ELOVL4 "CT118, SCA34, STGD2, STGD3" ENSG00000118402 "ELOVL fatty acid elongase 4" Q9GZR5 6 79914814-79947553 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, FDA approved drug targets, Ichthyosis, Mental retardation, Neurodegeneration, Spinocerebellar ataxia, Stargardt disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 105.5;retina: 176.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 63.8;Cone photoreceptor cells: 148.0;Excitatory neurons: 55.3;Rod photoreceptor cells: 355.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "MAIT T-cell: 23.7" "Lineage enriched" "Detected in single" 238 "T-cells: 23.7" "Cell line enhanced" "Detected in many" "JURKAT: 41.2;MOLT-4: 32.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (1.67e-2)" "unprognostic (8.58e-3)" "unprognostic (2.38e-2)" "unprognostic (3.08e-6)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (1.27e-1)" "unprognostic (1.39e-1)" "unprognostic (1.85e-1)" "unprognostic (3.46e-1)" "unprognostic (6.91e-3)" "unprognostic (3.39e-1)" "unprognostic (1.38e-2)" "unprognostic (3.45e-3)" "unprognostic (1.66e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (6.27e-4)" 0.7 2.0 7.1 1.1 7.0 0.1 4.1 10.0 15.4 3.5 9.7 1.8 0.6 2.2 1.0 10.6 0.7 1.6 0.9 7.8 9.9 1.5 0.1 0.3 0.4 14.4 5.3 1.7 0.5 10.8 6.4 1.7 15.0 4.0 1.0 176.7 2.8 1.7 0.2 43.1 0.8 2.7 4.3 0.5 0.9 5.7 7.4 105.5 1.5 0.5 1.7 1.2 4.0 7.2 0.0 0.8 10.8 12.0 8.8 8.5 1.6 5.6 6.1 4.7 10.2 1.5 0.0 0.0 1.0 7.7 19.3 1.1 14.1 7.9 3.5 0.0 18.2 0.4 2.2 0.0 8.1 4.4 1.7 6.9 2.9 4.8 4.9 6.8 7.8 41.2 0.0 0.0 10.0 1.9 32.8 0.0 10.4 0.0 5.6 0.0 15.5 0.0 0.1 0.0 14.2 4.2 6.0 9.6 1.7 7.4 3.8 0.3 0.8 2.1 4.1 3.2 4.3 7.2 15.3 0.0 5.0 0.0 3.3 0.0 0.0 0.0 2.3 0.0 23.7 0.0 3.3 3.9 0.0 0.0 0.6 1.6 0.0 0.0 0.0 0.0 0.2 0.9 7.1 7.0 10.0 15.4 7.8 9.9 14.4 5.3 15.0 4.3 7.4 7.2 0.7 0.0 0.0 7.5 0.2 11.3 2.3 7.5 15.4 63.8 0.7 1.7 0.9 0.0 3.9 0.0 148.0 0.9 1.7 0.0 0.0 0.1 6.3 0.3 7.0 2.2 8.9 0.0 55.3 0.0 1.5 6.5 0.0 0.1 0.0 1.5 0.0 0.0 0.2 42.1 53.0 0.5 6.1 0.3 1.5 2.1 1.2 0.2 3.6 8.4 0.1 50.7 0.0 20.1 8.6 0.0 1.1 3.4 0.3 3.1 0.0 2.3 0.5 355.3 0.0 2.0 4.3 15.4 15.4 14.8 37.8 1.0 2.6 1.3 0.2 0.7 EMILIN1 "DKFZp586M121, gp115" ENSG00000138080 "Elastin microfibril interfacer 1" Q9Y6C2 2 27078615-27086403 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 64.5;Fibroblasts: 111.3;Hepatic stellate cells: 45.0;Leydig cells: 85.1;Peritubular cells: 167.3;Sertoli cells: 72.3;Smooth muscle cells: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 98.2;BJ hTERT+: 65.0;HHSteC: 99.0;HSkMC: 109.6;SH-SY5Y: 129.4;U-138 MG: 63.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002822 Supported "Secreted to extracellular matrix" NA NA 4300000 "Cluster 49: Eosinophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA002822: AB_1078738" "unprognostic (3.14e-1)" "unprognostic (2.44e-2)" "unprognostic (3.92e-2)" "unprognostic (3.42e-2)" "unprognostic (3.26e-2)" "unprognostic (1.46e-1)" "unprognostic (3.07e-1)" "unprognostic (2.89e-2)" "unprognostic (4.10e-3)" "unprognostic (3.07e-2)" "unprognostic (1.85e-1)" "unprognostic (7.97e-2)" "prognostic unfavorable (8.13e-9)" "unprognostic (8.96e-3)" "unprognostic (3.77e-2)" "unprognostic (1.20e-2)" "unprognostic (5.70e-3)" 55.5 55.7 6.9 47.0 7.1 1.9 43.6 6.4 7.1 139.8 4.6 223.5 24.9 206.3 7.4 23.3 129.2 35.4 68.9 5.9 7.5 55.5 42.4 100.7 11.7 13.0 7.6 172.4 21.2 1.4 26.9 16.2 9.5 96.4 7.9 0.3 17.5 52.1 10.3 19.1 72.0 50.3 8.3 118.1 87.6 16.9 10.4 2.4 29.7 2.6 2.2 142.9 70.2 8.6 0.9 0.7 5.9 0.9 35.8 49.0 1.1 98.2 65.0 20.7 29.7 0.5 0.8 0.6 0.9 56.6 0.1 0.9 0.2 0.2 3.8 3.1 1.3 1.8 0.5 43.9 99.0 1.5 27.0 109.6 0.1 14.2 0.0 0.2 0.2 1.3 1.0 0.9 4.3 1.1 0.9 28.8 3.2 0.5 0.7 15.6 1.3 1.2 0.0 0.4 1.6 129.4 0.3 0.5 1.1 0.4 0.4 2.5 11.9 63.6 2.0 7.6 0.4 1.7 1.8 1.1 0.7 1.3 17.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.2 0.0 6.9 7.1 6.4 7.1 5.9 7.5 13.0 7.6 9.5 8.3 10.4 8.6 5.2 0.0 0.5 6.5 0.4 3.3 0.2 0.0 0.0 0.6 0.8 7.1 2.9 1.5 0.0 0.0 0.0 1.6 0.6 0.2 0.0 0.4 0.6 1.9 64.5 6.3 0.0 4.0 0.2 0.4 1.5 111.3 0.5 1.3 4.5 0.2 45.0 1.0 6.4 0.0 0.3 0.3 0.0 2.5 5.8 10.0 85.1 4.1 10.6 8.4 0.5 3.6 0.0 0.5 0.3 0.8 0.1 167.3 0.8 0.2 0.5 1.0 0.0 1.1 72.3 35.3 52.4 0.6 0.4 0.4 3.1 2.9 1.3 10.7 0.1 0.1 EPHA3 "ETK, ETK1, HEK, HEK4, TYRO4" ENSG00000044524 "EPH receptor A3" P29320 3 89107621-89482134 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 31.5" "Group enriched" "Detected in some" 4 "Excitatory neurons: 70.6;Inhibitory neurons: 106.6;Microglial cells: 103.0;Oligodendrocytes: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AF22: 197.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010462, HPA069390" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear membrane, Plasma membrane, Cytosol" "Nucleoplasm, Actin filaments" "CAB010462: AB_2099218, HPA069390: " "unprognostic (1.48e-3)" "unprognostic (2.30e-2)" "unprognostic (4.95e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (1.47e-2)" "unprognostic (2.03e-1)" "unprognostic (9.10e-3)" "unprognostic (1.24e-3)" "unprognostic (7.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (3.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-2)" 5.4 1.0 2.1 1.8 1.3 0.0 2.3 0.2 3.8 12.3 0.1 3.8 2.3 5.5 0.2 3.2 1.3 18.8 8.2 2.2 0.7 1.3 4.9 2.4 3.6 3.3 0.9 4.1 2.1 1.0 0.9 20.1 4.0 31.5 6.2 8.0 2.2 7.1 0.8 0.7 2.4 7.9 0.8 0.9 2.5 1.0 1.7 1.0 11.0 6.3 3.2 14.3 6.4 2.2 0.0 0.0 197.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 11.2 0.2 0.7 0.0 2.4 0.0 0.0 11.8 0.0 0.0 1.7 2.0 0.0 3.9 0.0 0.0 0.6 0.0 2.5 0.1 0.3 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.1 0.0 0.5 0.1 0.1 36.1 0.1 0.0 0.0 1.7 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.3 0.2 3.8 2.2 0.7 3.3 0.9 4.0 0.8 1.7 2.2 2.2 0.0 0.0 5.5 0.0 0.5 0.3 0.0 0.6 6.4 0.0 0.1 2.4 0.0 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.5 1.8 0.0 0.0 70.6 0.0 0.1 18.1 0.5 0.0 0.0 0.0 1.1 0.0 0.1 20.2 106.6 0.0 0.0 0.0 0.7 1.6 2.1 0.1 0.0 103.0 0.0 4.7 0.0 2.5 48.0 0.0 0.0 8.2 0.0 0.1 0.0 0.0 0.0 18.7 6.6 0.7 19.2 0.1 0.0 0.3 0.3 0.5 0.2 1.3 0.0 0.1 ETV4 "E1A-F, E1AF, PEA3" ENSG00000175832 "ETS variant transcription factor 4" P43268 17 43527844-43579620 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 23.3;Cholangiocytes: 17.2;Distal tubular cells: 17.6;Enteroendocrine cells: 14.9;Extravillous trophoblasts: 19.8;Syncytiotrophoblasts: 14.9" "Cancer enhanced" "Detected in all" "testis cancer: 80.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 177.7;Hep G2: 173.0;SK-MEL-30: 197.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005768 Approved Supported "Nucleoli rim,Mitotic chromosome" Yes No "Cluster 24: Salivary gland - Salivary secretion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoli rim" "Mitotic chromosome" "HPA005768: AB_1848294" "unprognostic (2.32e-1)" "unprognostic (7.33e-2)" "unprognostic (2.14e-1)" "unprognostic (2.51e-1)" "unprognostic (1.97e-2)" "unprognostic (3.14e-3)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.58e-2)" "unprognostic (5.34e-2)" "unprognostic (8.13e-2)" "unprognostic (7.05e-2)" "unprognostic (3.01e-1)" "unprognostic (7.79e-2)" "unprognostic (2.03e-1)" "unprognostic (7.08e-2)" "prognostic favorable (7.60e-4)" "unprognostic (1.69e-1)" 0.5 2.4 1.2 1.0 1.6 0.0 7.0 0.8 2.2 3.6 0.0 2.0 6.1 2.4 1.0 9.2 2.5 6.4 3.1 1.3 0.8 5.4 1.2 2.2 0.6 1.0 0.9 0.4 7.8 7.9 14.7 5.2 1.4 4.5 1.7 3.0 4.6 3.6 1.3 6.4 4.2 1.4 0.3 0.4 3.8 1.2 0.7 0.3 6.9 2.5 4.8 2.1 5.3 0.9 24.5 67.0 80.4 177.7 3.1 20.1 17.9 7.9 21.1 14.9 15.2 38.1 33.9 0.1 4.3 4.1 36.6 43.6 2.7 40.2 13.2 0.8 0.5 2.3 10.7 173.0 4.3 47.0 20.9 3.6 1.4 56.8 35.0 16.8 32.1 0.3 48.9 0.1 31.0 9.8 0.2 82.9 116.9 123.1 110.9 99.8 9.8 58.9 33.0 17.3 0.1 71.4 2.1 4.5 197.0 43.8 0.8 13.9 15.1 10.6 52.0 15.7 22.1 7.3 47.8 0.1 18.9 8.9 63.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 1.6 0.8 2.2 1.3 0.8 1.0 0.9 1.4 0.3 0.7 0.9 0.2 0.0 0.0 1.3 0.0 1.9 2.5 3.6 23.3 3.2 10.4 12.3 1.1 17.2 2.4 0.0 0.0 2.3 0.1 1.1 17.6 6.5 3.1 0.7 0.3 1.5 14.9 0.0 1.6 1.0 19.8 1.9 3.1 1.6 0.0 0.2 0.7 0.0 0.8 0.0 1.0 4.0 2.0 0.3 0.3 6.0 0.3 0.2 3.6 1.0 0.0 10.9 0.0 1.0 0.0 3.7 3.3 0.4 0.0 0.9 1.9 0.1 1.0 0.3 0.0 2.1 1.7 0.0 1.3 3.6 1.1 14.9 0.3 0.1 7.7 4.3 EVA1B "C1orf78, FAM176B, FLJ10647" ENSG00000142694 "Eva-1 homolog B" Q9NVM1 1 36322031-36324154 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 143.9;Extravillous trophoblasts: 250.3;Syncytiotrophoblasts: 161.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 23.3;BJ: 29.0;BJ hTERT+: 22.4;HSkMC: 20.4;NB-4: 41.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041928, HPA043537" Approved Approved Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA041928: AB_2677752, HPA043537: AB_2678538" "prognostic favorable (4.58e-4)" "unprognostic (5.66e-3)" "unprognostic (1.04e-3)" "unprognostic (3.20e-2)" "unprognostic (1.22e-2)" "unprognostic (4.00e-3)" "prognostic unfavorable (4.82e-4)" "unprognostic (1.45e-1)" "unprognostic (8.33e-2)" "unprognostic (1.48e-1)" "unprognostic (1.09e-1)" "unprognostic (2.60e-1)" "prognostic unfavorable (4.79e-5)" "unprognostic (1.87e-2)" "unprognostic (3.96e-2)" "unprognostic (1.39e-1)" "unprognostic (2.02e-1)" 26.8 19.4 5.5 3.4 5.4 2.0 35.8 5.5 6.4 41.8 7.5 19.8 2.5 34.0 0.6 12.2 21.9 1.3 19.9 5.0 5.9 39.2 8.5 26.1 1.9 6.8 6.4 30.2 7.8 1.9 9.4 9.0 6.0 29.0 0.4 0.0 28.7 2.9 5.7 24.0 15.8 1.6 7.0 37.6 14.2 7.5 6.6 0.5 33.9 1.0 0.5 22.0 30.1 5.7 0.7 2.7 1.6 3.0 7.9 23.3 6.8 29.0 22.4 5.4 6.3 0.2 2.1 0.0 8.5 9.2 1.0 0.2 0.2 1.1 1.1 3.3 6.0 3.6 0.6 1.3 17.4 0.1 0.6 20.4 0.0 6.9 0.3 0.9 8.7 0.1 1.4 1.0 3.6 0.2 0.1 41.7 1.7 0.0 10.4 1.5 0.3 7.1 4.6 0.0 0.1 3.9 2.8 1.1 13.3 1.1 0.0 2.7 12.7 7.9 0.0 10.5 2.7 0.3 0.0 0.1 2.9 1.8 7.1 4.0 0.9 0.0 0.2 0.3 0.6 0.0 0.3 0.5 0.5 0.0 0.0 0.0 1.7 1.6 0.1 0.0 1.2 0.1 5.5 5.4 5.5 6.4 5.0 5.9 6.8 6.4 6.0 7.0 6.6 5.7 82.8 0.0 0.0 2.3 6.2 16.2 19.3 7.3 0.0 0.0 143.9 90.6 2.2 1.5 5.1 7.3 0.0 54.7 8.4 0.3 1.9 20.2 7.1 9.4 88.4 53.9 0.0 0.8 0.0 15.2 250.3 56.6 0.0 15.2 4.5 15.7 84.9 0.9 48.7 0.0 0.0 0.1 6.1 41.3 28.8 24.8 50.7 30.4 12.4 5.6 10.2 14.1 4.1 0.0 0.1 28.9 1.1 48.5 7.9 56.6 0.4 7.7 5.6 0.9 26.3 7.8 98.4 8.4 3.3 0.7 12.4 161.3 9.7 58.2 0.5 30.3 F2R "CF2R, PAR-1, PAR1, TR" ENSG00000181104 "Coagulation factor II thrombin receptor" P25116 5 76716126-76735770 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 69.5" "Cell type enriched" "Detected in many" 5 "Hepatic stellate cells: 307.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 25.4" "Group enriched" "Detected in many" 14 "NK-cells: 7.0;T-cells: 25.4" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 196.9;HUVEC TERT2: 366.2;WM-115: 345.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008973, CAB012962" Approved NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB008973: , CAB012962: AB_2533198" "unprognostic (3.03e-1)" "unprognostic (7.76e-2)" "unprognostic (5.55e-2)" "unprognostic (7.76e-2)" "unprognostic (7.14e-2)" "unprognostic (3.46e-1)" "unprognostic (2.51e-1)" "unprognostic (3.75e-2)" "unprognostic (5.37e-2)" "unprognostic (1.36e-1)" "unprognostic (1.36e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (2.21e-7)" "unprognostic (2.72e-3)" "unprognostic (1.30e-1)" "unprognostic (1.12e-1)" "unprognostic (6.74e-3)" 14.5 13.5 1.2 12.1 1.4 4.0 18.3 1.6 1.5 15.4 1.6 10.0 14.2 23.2 4.2 11.1 3.9 39.5 30.4 1.2 1.5 19.1 23.9 22.8 16.2 2.5 2.6 2.9 9.9 7.3 4.3 10.5 2.1 7.2 11.6 0.7 30.5 12.0 3.6 45.7 18.8 18.8 1.8 69.5 10.3 8.8 1.9 4.9 15.2 11.9 8.6 15.4 4.5 1.5 5.7 17.5 53.3 8.8 98.4 170.5 2.6 30.3 102.5 19.5 69.8 3.9 47.0 0.1 50.1 13.0 88.1 13.2 23.1 18.1 36.6 4.4 19.3 120.2 3.8 14.7 147.7 0.6 4.9 96.9 60.2 37.2 10.5 196.9 366.2 21.4 22.8 22.1 40.1 2.4 9.6 0.4 17.0 0.3 93.5 17.1 31.9 4.3 91.2 0.8 6.3 28.7 8.9 0.2 45.2 48.0 0.7 1.3 169.0 121.8 26.7 1.3 56.7 59.0 18.5 0.2 32.4 2.3 345.5 1.1 0.2 0.4 25.4 0.5 6.5 0.6 5.7 17.7 0.0 0.2 0.9 12.7 1.1 7.0 0.1 0.3 0.6 11.2 1.2 1.4 1.6 1.5 1.2 1.5 2.5 2.6 2.1 1.8 1.9 1.5 25.8 0.0 9.2 1.6 4.4 17.2 0.7 9.3 1.2 3.5 3.4 2.4 2.6 7.2 4.5 7.3 0.0 0.2 56.2 0.3 0.0 2.0 10.7 2.8 47.1 51.8 6.6 11.6 1.0 2.2 0.4 39.5 8.2 5.4 6.3 13.0 307.0 4.3 2.1 0.0 3.3 3.9 16.2 16.6 10.7 6.0 0.9 5.4 12.4 5.6 1.1 0.1 54.6 0.5 0.1 10.8 0.2 10.5 35.8 1.4 0.5 3.4 4.2 1.4 0.0 8.1 24.9 12.7 5.4 1.5 40.1 0.3 40.1 9.5 1.3 0.4 F2RL1 "GPR11, PAR2" ENSG00000164251 "F2R like trypsin receptor 1" P55085 5 76818933-76835315 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 59.4;stomach 1: 44.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 109.9;Distal enterocytes: 124.7;Gastric mucus-secreting cells: 74.5;Glandular and luminal cells: 74.7;Paneth cells: 86.1;Suprabasal keratinocytes: 168.4;Urothelial cells: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 42.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 42.0" "Cell line enhanced" "Detected in many" "PC-3: 126.0;RPTEC TERT1: 205.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB012989, HPA014091" Approved Approved "Plasma membrane" NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB012989: AB_2533199, HPA014091: AB_2668939" "unprognostic (1.29e-2)" "unprognostic (4.05e-2)" "prognostic favorable (3.88e-4)" "unprognostic (1.98e-2)" "unprognostic (8.22e-2)" "prognostic unfavorable (5.88e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (8.92e-4)" "unprognostic (6.13e-2)" "unprognostic (4.07e-1)" "unprognostic (2.16e-3)" "unprognostic (1.52e-2)" "prognostic favorable (5.86e-7)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "unprognostic (3.76e-2)" "unprognostic (9.73e-2)" 1.0 1.3 0.8 6.2 0.9 1.7 8.0 0.5 0.8 3.6 8.9 59.4 45.8 2.9 4.8 8.2 8.2 29.9 4.6 0.5 0.8 31.8 7.1 4.1 1.4 1.7 2.2 0.5 23.6 5.2 1.5 3.9 1.4 5.0 53.0 2.6 8.9 11.5 0.3 37.5 41.0 2.7 1.0 3.8 44.0 0.6 0.9 1.1 8.3 0.2 1.6 27.5 5.8 0.8 32.7 52.1 4.3 0.2 1.5 4.0 33.1 1.6 17.1 0.9 2.7 45.0 81.8 0.0 69.5 3.7 78.1 54.4 27.1 24.0 1.5 0.1 26.8 0.8 1.0 32.8 10.6 0.0 0.3 5.5 67.3 8.0 49.8 8.0 84.9 7.8 0.4 0.0 0.1 17.6 3.8 0.1 5.7 17.9 126.0 0.1 0.0 0.8 205.9 58.5 2.1 0.4 12.3 12.6 0.3 48.5 5.3 0.3 57.1 0.1 31.8 0.1 0.3 4.8 1.0 0.1 18.7 0.0 1.4 11.9 10.0 1.8 0.4 3.2 2.1 0.5 3.8 1.9 4.7 0.1 3.4 2.1 42.0 0.7 0.5 0.5 1.0 4.0 0.8 0.9 0.5 0.8 0.5 0.8 1.7 2.2 1.4 1.0 0.9 0.8 0.3 9.6 3.7 0.0 0.9 109.9 17.8 4.5 10.8 0.5 10.5 6.3 0.3 32.9 12.7 31.3 0.0 5.4 0.2 124.7 1.9 28.0 0.0 40.9 5.1 1.2 13.1 2.5 0.2 15.0 7.9 2.9 74.5 74.7 2.5 1.0 1.1 9.6 0.9 0.0 1.4 50.8 4.1 1.9 3.8 0.0 0.0 2.1 1.8 1.0 2.6 0.0 0.0 0.0 0.0 44.7 86.1 0.0 0.1 34.1 62.9 19.3 25.0 2.0 0.0 0.4 2.8 0.9 1.3 37.0 168.4 2.1 2.1 0.1 50.7 116.0 F2RL2 PAR3 ENSG00000164220 "Coagulation factor II thrombin receptor like 2" O00254 5 76615482-76623413 "G-protein coupled receptors, Predicted membrane proteins" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.9;gallbladder: 6.8" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 2.3;Fibroblasts: 3.9;Hepatic stellate cells: 10.0;Rod photoreceptor cells: 5.5" "Cancer enhanced" "Detected in many" "breast cancer: 9.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 9 "basophil: 10.4" "Lineage enriched" "Detected in many" 9 "granulocytes: 10.4" "Cell line enhanced" "Detected in many" "BJ hTERT+: 53.5;HBF TERT88: 33.8;HEL: 78.4;hTEC/SVTERT24-B: 34.8;hTERT-RPE1: 73.2;U-138 MG: 54.0;WM-115: 69.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (1.35e-3)" "unprognostic (5.71e-3)" "prognostic favorable (4.69e-4)" "unprognostic (6.71e-2)" "unprognostic (4.16e-3)" "unprognostic (3.56e-2)" "unprognostic (9.71e-2)" "unprognostic (8.49e-2)" "unprognostic (3.78e-2)" "unprognostic (1.43e-1)" "unprognostic (1.14e-1)" "unprognostic (3.20e-1)" "unprognostic (2.24e-8)" "unprognostic (7.64e-2)" "unprognostic (8.98e-2)" "unprognostic (1.29e-1)" "unprognostic (1.73e-2)" 0.3 0.4 1.2 1.8 1.5 0.3 3.8 4.4 0.2 1.3 0.1 3.5 1.6 2.3 0.1 0.8 0.3 6.8 1.8 0.2 4.4 0.3 2.0 0.6 0.1 3.9 4.7 0.1 1.0 0.3 0.4 0.2 2.9 0.3 1.7 5.0 3.7 0.1 0.0 2.3 2.3 3.8 2.3 0.3 1.3 0.0 6.9 0.8 0.2 0.5 0.3 1.0 0.3 0.5 0.0 2.0 0.2 0.2 2.3 12.1 0.0 31.3 53.5 8.3 30.0 0.0 0.1 0.0 1.8 0.2 24.8 0.1 0.0 0.2 33.8 0.0 0.1 78.4 0.7 0.2 4.7 0.1 0.1 6.7 0.2 34.8 0.1 73.2 2.9 0.2 0.0 0.1 3.0 0.0 0.0 0.0 2.8 0.0 0.3 0.0 0.2 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 54.0 16.2 2.4 0.4 2.7 0.0 0.0 6.4 0.0 69.8 10.4 0.4 0.1 0.7 0.2 0.6 0.1 0.7 0.4 0.1 0.1 0.3 0.7 0.9 1.1 0.1 1.1 0.9 0.0 1.2 1.5 4.4 0.2 0.2 4.4 3.9 4.7 2.9 2.3 6.9 0.5 0.0 0.0 0.0 0.3 0.3 0.9 0.1 0.0 0.0 0.2 0.1 0.1 0.3 0.0 0.0 1.8 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.4 2.3 1.0 0.0 0.0 0.2 0.0 0.0 3.9 1.1 0.3 0.0 0.0 10.0 0.3 0.1 0.0 0.3 0.0 0.0 1.2 1.1 0.0 0.0 0.3 0.0 0.0 0.7 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.5 0.0 0.0 0.1 0.6 0.0 0.9 0.0 0.0 0.1 FAM171B "FLJ34104, KIAA1946" ENSG00000144369 "Family with sequence similarity 171 member B" Q6P995 2 186694060-186765959 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.8" "Group enriched" "Detected in many" 5 "Astrocytes: 258.6;Bipolar cells: 141.4;Excitatory neurons: 126.5;Inhibitory neurons: 114.2;Oligodendrocyte precursor cells: 102.1;Oligodendrocytes: 78.5" "Cancer enriched" "Detected in many" 5 "glioma: 15.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 43.7;U-138 MG: 29.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010639, HPA013434" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Mitochondria" "HPA010639: AB_1852447, HPA013434: AB_2262499" "unprognostic (2.52e-1)" "unprognostic (7.75e-3)" "unprognostic (1.27e-1)" "unprognostic (1.04e-2)" "unprognostic (4.03e-2)" "unprognostic (9.43e-2)" "unprognostic (6.78e-3)" "unprognostic (2.68e-1)" "unprognostic (1.88e-2)" "unprognostic (1.52e-1)" "unprognostic (4.24e-3)" "unprognostic (1.47e-1)" "prognostic unfavorable (9.51e-7)" "unprognostic (4.63e-3)" "unprognostic (1.52e-1)" "unprognostic (2.24e-3)" "prognostic unfavorable (5.03e-4)" 2.9 14.4 36.1 1.5 52.2 0.5 3.4 8.3 54.8 6.6 0.0 1.8 1.0 7.5 2.1 1.9 2.7 4.9 1.4 52.8 33.0 1.2 0.3 1.4 1.2 15.0 16.9 10.2 1.0 7.6 10.7 3.3 17.6 2.7 2.0 24.1 23.0 2.3 0.7 3.7 1.4 4.4 17.2 1.5 2.0 0.9 28.3 2.8 2.2 3.6 1.1 2.2 2.2 30.1 4.2 4.9 7.2 22.6 20.9 15.7 0.1 4.5 8.0 5.5 7.8 13.6 21.9 0.0 1.6 12.9 9.3 0.5 9.9 4.3 7.8 0.0 5.7 5.1 2.1 0.0 1.6 1.5 1.7 20.2 1.8 4.2 3.4 7.1 12.1 3.9 0.0 43.7 10.5 2.9 3.0 0.0 9.6 0.0 4.9 0.0 13.9 1.0 8.5 15.8 22.4 12.2 2.3 1.4 6.1 4.2 1.7 1.0 7.1 29.7 3.9 0.5 2.9 11.5 12.0 0.0 9.2 0.0 4.2 0.2 0.1 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.4 0.2 0.2 0.0 0.0 36.1 52.2 8.3 54.8 52.8 33.0 15.0 16.9 17.6 17.2 28.3 30.1 9.1 0.0 0.0 258.6 0.1 8.9 2.8 1.2 4.0 141.4 10.7 5.7 0.8 5.7 5.7 0.0 14.6 11.4 0.5 0.0 0.0 1.0 1.3 1.5 13.0 14.4 4.8 1.3 126.5 0.4 0.8 14.1 2.6 4.7 0.0 0.8 6.8 0.1 2.0 23.5 114.2 0.0 4.1 0.3 2.8 4.0 7.8 1.0 3.6 18.7 0.7 16.2 0.0 102.1 78.5 0.7 0.0 13.9 0.2 1.4 0.0 0.2 2.6 17.0 0.0 8.6 4.5 0.4 1.5 0.6 5.3 8.2 0.9 2.6 0.0 1.1 FAM24B "AC073585.2, MGC45962" ENSG00000213185 "Family with sequence similarity 24 member B" Q8N5W8 10 122849078-122879641 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 15.0" "Cell type enhanced" "Detected in many" "Distal tubular cells: 50.9;Early spermatids: 28.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "hTERT-HME1: 135.5;LHCN-M2: 181.8;TIME: 58.3" HPA052490 Supported "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 43: Testis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" "HPA052490: AB_2681851" "unprognostic (4.03e-2)" "unprognostic (4.27e-2)" "unprognostic (3.13e-3)" "unprognostic (8.40e-5)" "unprognostic (2.55e-2)" "unprognostic (3.31e-2)" "unprognostic (6.42e-7)" "unprognostic (2.99e-1)" "unprognostic (7.06e-3)" "unprognostic (3.00e-1)" "unprognostic (5.89e-2)" "unprognostic (3.59e-2)" "unprognostic (1.78e-1)" "unprognostic (2.58e-1)" "unprognostic (9.23e-2)" "unprognostic (1.25e-1)" "unprognostic (8.81e-3)" 2.1 1.3 4.9 2.6 5.0 2.6 3.0 4.9 6.4 2.8 3.7 2.8 2.3 2.3 2.9 2.4 2.2 2.1 1.5 5.2 6.3 15.0 0.9 2.4 5.9 5.3 5.0 2.9 7.8 1.0 10.9 0.4 5.2 3.0 4.0 5.9 1.9 1.4 0.9 4.2 3.6 1.6 4.9 3.8 3.1 9.2 5.2 4.9 2.4 0.2 4.7 2.6 2.3 5.8 8.1 12.8 3.1 0.1 1.9 3.7 4.0 11.8 11.1 4.8 4.4 14.2 16.6 3.0 3.6 6.5 1.4 5.2 0.0 7.1 13.1 14.0 5.3 23.8 18.4 7.6 10.4 0.0 13.8 4.3 0.9 10.4 135.5 0.9 12.6 15.5 9.5 6.0 181.8 7.3 13.9 13.9 5.0 8.1 13.3 0.0 18.5 2.8 8.6 7.2 8.6 3.7 5.5 2.9 15.0 7.7 4.7 14.1 58.3 1.4 6.7 5.0 1.2 6.5 7.1 18.0 9.7 23.3 0.0 2.2 1.5 1.0 1.7 1.5 0.6 4.2 3.4 2.4 2.1 2.3 3.5 2.1 1.0 2.1 1.5 8.1 3.6 1.2 4.9 5.0 4.9 6.4 5.2 6.3 5.3 5.0 5.2 4.9 5.2 5.8 2.5 0.0 0.5 0.0 7.1 6.6 1.6 4.2 14.2 3.6 3.7 5.8 0.2 2.8 1.2 9.2 0.0 0.1 7.7 1.6 50.9 4.3 28.2 0.5 0.7 1.9 4.8 6.5 0.0 7.3 0.2 3.8 2.0 0.6 8.9 0.5 1.8 0.8 1.2 1.7 0.0 3.5 12.2 4.1 2.9 4.1 3.7 3.3 1.8 0.0 3.5 2.9 8.2 0.0 0.0 8.7 2.7 4.1 2.7 2.0 2.3 1.8 1.2 4.3 0.0 1.7 2.3 12.9 4.6 5.5 5.4 0.0 6.7 0.2 3.5 1.2 FAP DPPIV ENSG00000078098 "Fibroblast activation protein alpha" Q12884 2 162170684-162245151 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 31.4;smooth muscle: 26.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 67.6;Fibroblasts: 43.4;Microglial cells: 17.8;Muller glia cells: 57.5;Smooth muscle cells: 25.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 192.2;ASC TERT1: 202.3;BJ hTERT+: 167.8;hTERT-RPE1: 209.1;U-138 MG: 167.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "cerebral cortex: 3.1;hippocampal formation: 2.4" HPA059739 Uncertain "Secreted to blood" NA NA 108000000 56000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA059739: AB_2684117" "unprognostic (7.48e-3)" "unprognostic (7.87e-3)" "unprognostic (4.10e-2)" "unprognostic (5.04e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (4.82e-4)" "unprognostic (2.01e-2)" "unprognostic (1.05e-2)" "unprognostic (3.30e-2)" "unprognostic (4.89e-2)" "unprognostic (4.59e-2)" "unprognostic (3.52e-1)" "unprognostic (7.32e-11)" "unprognostic (1.72e-3)" "unprognostic (9.84e-3)" "unprognostic (7.97e-2)" "unprognostic (4.49e-3)" 5.8 0.2 0.9 5.2 0.9 0.0 10.1 0.4 0.9 15.2 0.0 3.5 0.5 31.4 8.5 3.6 4.8 22.3 4.9 0.3 1.4 0.7 0.2 4.0 1.5 0.6 0.5 3.0 2.5 0.7 0.5 23.1 0.6 1.9 2.5 6.4 4.7 5.8 4.4 2.8 0.9 26.4 0.2 0.4 1.0 1.5 1.0 0.5 2.8 7.5 1.5 15.5 3.6 0.7 0.0 0.0 0.0 0.0 192.2 202.3 0.4 82.8 167.8 16.6 25.4 0.0 0.0 0.0 0.6 31.3 0.0 0.1 0.0 5.1 8.0 0.0 0.0 0.1 1.2 0.0 19.5 0.0 0.0 66.2 1.2 28.1 5.2 209.1 0.1 0.0 0.0 0.0 53.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 8.5 0.0 9.0 0.2 0.1 0.0 84.3 167.3 3.1 41.4 0.4 0.0 0.1 0.0 37.5 0.1 45.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.4 0.9 0.3 1.4 0.6 0.5 0.6 0.2 1.0 0.7 3.9 0.0 0.0 5.5 0.2 4.5 0.1 7.0 0.0 1.8 0.3 0.5 0.4 0.0 0.3 0.0 0.0 0.9 0.1 0.0 0.0 0.2 6.7 3.4 67.6 6.4 4.9 0.0 13.3 0.2 1.9 43.4 0.0 6.2 0.0 0.0 1.4 0.0 0.9 1.7 0.3 1.4 0.0 0.0 2.6 4.1 8.4 0.8 3.6 17.8 0.0 57.5 0.0 0.5 4.2 1.0 0.0 0.0 0.3 0.0 0.0 1.2 0.2 2.0 0.0 4.7 25.2 2.3 0.4 0.4 4.3 1.8 0.8 1.3 0.2 0.0 FAS "APO-1, APT1, CD95, FAS1, TNFRSF6" ENSG00000026103 "Fas cell surface death receptor" P25445 10 88990531-89017059 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis "Calmodulin-binding, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 114.7" "Group enriched" "Detected in all" 5 "granulocytes: 114.7;T-cells: 96.2" "Cell line enhanced" "Detected in many" "HDLM-2: 83.4;Karpas-707: 109.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027444 Uncertain Supported "Nuclear bodies,Plasma membrane,Cytosol" "Secreted to blood" NA NA 11900000 420000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Nuclear bodies, Cytosol" "HPA027444: AB_10601378" "unprognostic (6.84e-2)" "unprognostic (2.88e-3)" "unprognostic (8.38e-3)" "unprognostic (1.94e-1)" "unprognostic (2.35e-2)" "unprognostic (9.56e-2)" "unprognostic (7.00e-2)" "unprognostic (2.05e-1)" "unprognostic (3.01e-1)" "unprognostic (7.70e-2)" "unprognostic (1.26e-2)" "unprognostic (1.98e-1)" "unprognostic (1.52e-3)" "unprognostic (2.10e-1)" "unprognostic (2.32e-2)" "unprognostic (4.95e-3)" "unprognostic (1.65e-1)" 14.1 26.3 3.6 17.0 3.6 20.8 10.9 2.9 4.7 12.7 2.8 16.4 7.0 12.8 10.3 10.8 14.8 15.7 7.5 3.6 3.7 7.2 23.3 21.7 18.9 4.6 3.1 20.1 3.7 2.7 3.7 10.4 4.0 8.9 23.3 3.3 6.5 9.3 2.3 9.4 9.2 15.0 3.5 11.2 4.4 2.6 3.9 14.4 7.3 2.6 15.6 12.9 10.2 4.3 22.7 8.2 5.4 13.9 37.0 51.3 0.0 51.8 50.2 1.7 9.1 0.1 23.4 4.7 19.0 52.1 9.6 4.0 1.0 44.8 3.2 83.4 8.7 0.4 5.2 14.7 31.6 3.4 1.6 69.2 38.7 31.4 66.0 24.5 4.7 17.8 0.0 109.0 44.0 1.4 6.4 3.4 0.6 0.2 1.8 1.4 0.5 5.0 60.7 7.3 0.4 0.2 7.7 0.0 0.8 7.0 13.9 1.0 9.5 15.8 9.0 15.2 12.3 45.3 5.3 0.4 11.8 10.2 4.5 43.1 9.4 30.9 9.9 12.3 13.8 7.5 27.6 19.6 11.5 4.0 3.1 10.0 114.7 3.1 22.1 0.2 96.2 12.8 3.6 3.6 2.9 4.7 3.6 3.7 4.6 3.1 4.0 3.5 3.9 4.3 10.3 57.7 13.8 40.1 12.8 45.9 109.7 53.1 39.9 0.0 5.5 9.5 3.5 12.8 27.5 9.2 0.0 0.4 16.3 24.9 0.0 6.3 11.3 9.2 22.3 8.9 8.4 9.5 8.8 4.3 0.2 35.4 8.6 15.5 3.8 4.9 2.2 19.3 5.5 1.7 2.8 14.4 8.2 7.0 31.7 4.9 19.0 17.7 12.4 17.8 20.9 14.5 10.3 8.0 0.7 6.5 8.7 13.9 32.2 46.0 15.6 14.4 26.3 0.7 6.6 26.8 29.1 11.3 1.1 28.5 43.9 0.4 48.4 11.8 24.4 30.0 FBLN7 "FLJ37440, TM14" ENSG00000144152 "Fibulin 7" Q53RD9 2 112138385-112188218 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 14.4;Fibroblasts: 16.6;Inhibitory neurons: 30.7;Melanocytes: 17.8;Skeletal myocytes: 19.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 26 "memory CD4 T-cell: 34.4;naive CD4 T-cell: 29.5;T-reg: 36.5" "Lineage enriched" "Detected in many" 35 "T-cells: 36.5" "Cell line enhanced" "Detected in many" "AF22: 24.5;BJ hTERT+: 17.7;hTERT-RPE1: 12.8;SCLC-21H: 15.8;SH-SY5Y: 12.6;U-2197: 25.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034992 Approved "Plasma membrane,Cell Junctions" "Secreted to extracellular matrix" NA NA 310000 "Cluster 20: T-cells - T-cell receptor" "Cluster 34: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Cell Junctions" "HPA034992: AB_10601469" "unprognostic (1.72e-1)" "unprognostic (1.47e-1)" "unprognostic (5.88e-2)" "unprognostic (4.88e-3)" "unprognostic (1.24e-1)" "unprognostic (1.70e-3)" "unprognostic (4.34e-2)" "unprognostic (4.80e-2)" "unprognostic (5.77e-2)" "unprognostic (2.01e-1)" "unprognostic (7.91e-2)" "unprognostic (2.02e-2)" "unprognostic (2.35e-2)" "unprognostic (3.11e-2)" "unprognostic (8.10e-2)" "unprognostic (1.21e-2)" "unprognostic (9.33e-2)" 6.5 4.0 0.8 4.3 0.6 0.7 7.8 4.0 6.4 10.3 0.4 1.8 1.1 4.8 2.8 1.9 7.1 3.4 2.5 2.1 3.8 1.5 5.2 2.7 9.8 9.2 4.4 1.4 2.4 6.9 12.2 3.2 9.7 3.3 1.3 2.5 2.5 3.1 1.4 5.5 2.9 2.2 2.2 5.6 3.0 0.5 4.1 8.6 10.7 2.5 6.0 2.5 7.5 1.1 0.0 0.1 24.5 0.0 2.6 1.9 0.1 5.5 17.7 5.9 9.2 0.0 0.2 0.0 0.1 8.3 1.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.9 1.1 1.2 0.0 0.0 1.9 0.1 9.9 0.0 12.8 1.4 0.3 0.0 0.0 2.1 0.0 0.7 0.1 0.6 0.0 0.5 0.0 0.0 6.6 0.3 0.0 15.8 12.6 0.1 0.1 0.7 0.1 0.7 0.2 5.2 0.8 0.7 25.4 0.8 0.0 0.0 0.0 0.8 0.0 2.1 0.0 0.0 0.0 0.4 0.0 1.3 0.0 34.4 0.4 0.0 0.0 29.5 1.0 0.0 0.0 0.0 1.0 36.5 6.2 0.8 0.6 4.0 6.4 2.1 3.8 9.2 4.4 9.7 2.2 4.1 1.1 1.4 3.2 0.5 0.3 0.7 4.5 1.0 0.3 0.0 3.8 1.0 2.4 1.1 0.0 0.0 0.0 0.0 4.0 0.2 0.0 0.0 0.3 1.7 1.2 5.9 2.6 0.0 0.0 14.4 0.2 10.1 16.6 0.0 1.2 1.3 0.7 0.4 2.2 0.5 3.3 30.7 0.0 0.0 0.0 4.0 3.6 0.3 0.4 17.8 1.9 0.0 2.3 0.0 6.6 0.9 0.6 0.0 5.3 0.1 0.4 0.1 0.5 0.3 7.6 6.6 19.3 7.8 0.1 0.4 0.1 3.8 1.5 7.7 0.2 0.0 0.3 FBN1 "FBN, MASS, MFS1, OCTD, SGS, WMS" ENSG00000166147 "Fibrillin 1" P35555 15 48408313-48645721 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Heparin-binding, Hormone" "Aortic aneurysm, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 60.9;placenta: 76.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 132.4;Fibroblasts: 388.5;Leydig cells: 236.1;Oligodendrocytes: 218.7;Peritubular cells: 227.2;Skeletal myocytes: 139.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 215.1;ASC TERT1: 460.7;fHDF/TERT166: 420.8;HSkMC: 251.3;hTERT-RPE1: 211.1;U-138 MG: 206.9;U-2197: 305.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002670, HPA017759, HPA021057, CAB058696, CAB068188" Enhanced Approved Cytosol "Secreted to blood" NA NA 520000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "CAB002670: , CAB058696: AB_2665596, CAB068188: AB_2665597, HPA017759: AB_1848584, HPA021057: AB_1848586" "unprognostic (3.97e-2)" "unprognostic (1.55e-2)" "unprognostic (2.40e-2)" "unprognostic (9.50e-2)" "unprognostic (1.51e-1)" "unprognostic (9.49e-2)" "unprognostic (2.00e-2)" "unprognostic (4.79e-2)" "unprognostic (7.82e-2)" "unprognostic (1.50e-2)" "unprognostic (2.78e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (7.44e-5)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.25e-2)" "unprognostic (8.69e-3)" "prognostic unfavorable (5.11e-4)" 60.9 4.4 1.4 14.5 5.4 3.4 13.7 2.8 2.8 36.0 9.5 8.3 3.8 15.2 6.3 12.6 12.2 27.3 23.5 0.8 2.0 2.7 2.9 10.0 3.7 5.2 6.0 28.4 3.3 3.0 2.5 76.7 3.7 8.0 11.7 1.3 4.6 13.2 4.5 5.7 6.6 35.7 2.3 6.4 6.0 7.1 4.7 2.9 18.6 21.2 3.5 18.8 9.9 5.0 0.1 5.2 19.8 22.4 215.1 460.7 0.2 175.8 62.9 51.1 32.4 0.1 0.3 0.1 7.9 420.8 0.4 0.7 3.9 0.6 45.9 20.7 1.2 2.0 88.5 0.2 120.7 0.8 0.3 251.3 0.1 135.9 15.6 211.1 55.5 1.6 0.0 0.4 55.6 0.0 1.5 0.2 4.0 0.2 7.1 0.1 17.0 0.2 5.9 0.5 0.2 12.9 0.0 2.2 0.1 15.3 0.2 1.4 106.8 206.9 6.2 305.8 37.6 1.2 1.0 0.0 138.9 0.3 13.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.4 5.4 2.8 2.8 0.8 2.0 5.2 6.0 3.7 2.3 4.7 5.0 50.0 0.0 1.3 34.9 0.4 25.6 0.8 1.5 0.6 6.1 1.3 3.4 14.2 0.0 5.8 12.9 0.0 132.4 0.4 0.0 0.0 0.2 8.7 4.2 105.2 36.1 0.0 5.5 82.3 0.6 40.8 388.5 3.1 2.0 1.3 22.5 34.6 0.6 15.3 0.0 123.5 0.0 0.0 0.8 39.0 22.8 236.1 5.7 42.7 30.0 2.3 0.8 0.0 76.9 218.7 1.7 0.0 227.2 1.7 0.7 0.1 0.6 3.3 0.2 26.3 139.5 55.8 3.3 3.4 0.8 20.6 65.8 4.3 51.3 0.0 0.2 FIBIN MGC24932 ENSG00000176971 "Fin bud initiation factor homolog" Q8TAL6 11 26994112-26997087 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 33.0;Fibroblasts: 80.8;Granulosa cells: 42.4;Leydig cells: 37.9;Oligodendrocyte precursor cells: 32.2;Peritubular cells: 35.0" "Cancer enhanced" "Detected in all" "glioma: 48.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 65.2;ASC TERT1: 41.8;fHDF/TERT166: 22.1;HHSteC: 88.2;HSkMC: 89.5;hTCEpi: 24.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040120 Uncertain "Intracellular and membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA040120: AB_10795243" "unprognostic (1.72e-1)" "unprognostic (2.61e-1)" "unprognostic (1.29e-1)" "unprognostic (9.04e-2)" "unprognostic (1.62e-2)" "unprognostic (5.42e-2)" "unprognostic (7.28e-2)" "unprognostic (1.03e-1)" "unprognostic (4.32e-2)" "unprognostic (5.08e-3)" "unprognostic (3.16e-2)" "unprognostic (2.20e-1)" "prognostic favorable (1.93e-5)" "prognostic unfavorable (6.72e-4)" "unprognostic (8.48e-2)" "prognostic unfavorable (1.85e-6)" "unprognostic (1.02e-2)" 32.3 4.9 11.0 7.7 10.6 0.0 25.1 11.4 10.8 35.6 6.1 27.8 2.2 26.1 8.0 11.3 35.7 7.9 32.6 10.8 10.7 15.2 2.0 27.2 2.8 10.6 12.7 18.5 3.8 0.3 2.6 12.6 11.7 17.0 2.6 0.6 17.6 61.3 17.1 16.7 12.0 17.1 11.4 14.1 21.1 1.3 11.6 2.1 13.4 14.5 0.9 16.3 58.3 11.7 0.0 0.0 1.0 0.0 65.2 41.8 0.1 2.1 5.7 0.2 0.9 0.0 0.0 0.0 0.0 22.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 88.2 0.0 0.0 89.5 24.0 1.1 0.0 1.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 4.2 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 10.6 11.4 10.8 10.8 10.7 10.6 12.7 11.7 11.4 11.6 11.7 2.5 0.0 0.0 17.9 0.0 6.6 1.6 33.0 1.8 0.3 1.9 0.9 1.2 11.5 4.0 11.0 0.0 1.2 0.0 0.1 11.7 0.6 0.1 0.0 0.1 1.0 0.0 0.0 0.5 0.0 0.9 80.8 0.0 0.0 0.0 42.4 6.1 0.5 1.8 0.0 0.1 0.0 12.2 0.0 10.3 0.3 37.9 0.8 7.2 0.0 0.0 19.8 0.0 32.2 0.1 0.1 0.0 35.0 0.1 0.2 0.0 4.3 0.9 0.6 0.0 3.7 7.4 0.1 0.3 0.8 5.1 1.9 0.5 3.9 0.0 0.0 FKBP10 "FKBP6, FKBP65, FLJ20683, FLJ22041, FLJ23833, hFKBP65" ENSG00000141756 "FKBP prolyl isomerase 10" Q96AY3 17 41812680-41823213 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 79.1;Fibroblasts: 100.0;Sertoli cells: 59.2;Smooth muscle cells: 65.3;Theca cells: 54.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 551.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051171, HPA057021" Enhanced Approved Mitochondria "Intracellular and membrane" NA NA 110000 "Cluster 22: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Mitochondria "HPA051171: AB_2681371, HPA057021: AB_2683312" "unprognostic (8.30e-2)" "prognostic unfavorable (4.16e-4)" "unprognostic (9.05e-2)" "unprognostic (1.71e-2)" "unprognostic (4.77e-2)" "unprognostic (2.95e-2)" "unprognostic (1.14e-2)" "unprognostic (9.98e-2)" "unprognostic (2.21e-2)" "unprognostic (7.57e-2)" "unprognostic (1.14e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.34e-2)" "unprognostic (5.77e-2)" "prognostic unfavorable (3.43e-5)" "prognostic unfavorable (4.99e-4)" 39.4 39.5 20.9 27.1 22.2 0.5 33.5 21.7 26.1 64.0 22.0 29.1 7.6 61.5 16.9 13.9 50.9 46.0 45.6 20.3 22.1 17.7 7.8 37.8 10.9 24.6 21.6 58.4 15.1 48.5 56.7 60.7 22.2 32.6 10.8 6.0 14.7 30.8 7.6 20.4 19.1 55.6 21.9 14.3 18.5 9.0 24.2 4.9 34.9 9.3 4.4 42.2 39.1 21.6 0.7 119.6 110.7 363.3 379.3 441.7 92.0 490.4 497.4 185.6 159.0 62.1 4.8 0.3 6.6 551.9 45.9 0.8 66.7 133.4 77.9 33.0 99.9 48.6 132.1 181.0 411.4 0.0 0.6 476.1 0.5 150.3 115.5 352.6 158.8 0.0 1.9 16.7 157.0 163.2 0.3 0.1 85.4 258.0 38.3 9.9 125.2 15.7 31.7 0.1 26.7 92.1 0.7 349.3 166.0 137.4 54.1 3.1 181.0 219.0 111.5 145.8 76.0 0.8 0.2 0.3 299.7 0.0 213.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 20.9 22.2 21.7 26.1 20.3 22.1 24.6 21.6 22.2 21.9 24.2 21.6 14.9 0.0 4.8 38.2 0.2 8.5 11.5 2.7 1.2 0.6 10.8 13.2 2.3 1.5 1.4 0.0 0.0 6.1 0.2 0.1 0.0 8.7 0.7 3.0 79.1 34.9 0.0 0.0 0.3 4.7 30.8 100.0 1.5 4.6 0.0 32.9 30.4 0.0 4.7 15.2 0.3 1.3 0.0 0.0 9.7 2.9 46.9 1.5 16.0 15.0 0.0 32.0 0.0 17.1 0.1 2.2 0.1 44.8 0.5 8.2 0.0 0.0 0.1 1.1 59.2 35.2 65.3 0.9 7.6 0.5 5.1 11.9 2.1 54.0 0.6 1.6 FOXP2 "CAGH44, SPCH1, TNRC10" ENSG00000128573 "Forkhead box P2" O15409 7 114086327-114693772 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.8" "Group enriched" "Detected in many" 4 "Excitatory neurons: 186.8;Microglial cells: 288.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 21.0;RH-30: 37.3;THP-1: 11.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000382, HPA000383, HPA001679" Enhanced Enhanced Nucleoplasm NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA000382: AB_1078908, HPA000383: AB_1078909, HPA001679: AB_2666415" "unprognostic (1.21e-1)" "unprognostic (7.85e-2)" "unprognostic (4.89e-2)" "unprognostic (8.83e-3)" "unprognostic (4.66e-1)" "unprognostic (3.69e-4)" "unprognostic (2.04e-2)" "unprognostic (6.22e-2)" "unprognostic (2.17e-1)" "unprognostic (6.70e-3)" "unprognostic (1.22e-1)" "unprognostic (1.77e-1)" "unprognostic (8.04e-2)" "unprognostic (4.16e-3)" "unprognostic (2.84e-1)" "unprognostic (9.81e-2)" "unprognostic (4.19e-2)" 1.9 1.3 1.8 1.9 1.3 0.4 2.0 0.0 10.1 5.0 0.0 18.8 2.5 8.0 1.7 6.1 3.4 3.5 1.4 2.7 0.9 2.0 2.5 1.5 1.0 1.5 6.9 9.7 4.6 0.6 0.9 0.5 1.9 2.2 5.2 3.2 2.8 1.4 3.2 3.7 3.2 7.7 0.0 0.5 4.2 1.3 2.6 0.2 4.9 1.8 0.7 6.1 4.3 5.2 0.4 3.2 21.0 0.0 4.9 6.2 1.3 3.5 3.6 0.7 0.4 1.6 0.3 0.3 0.8 1.2 0.1 0.5 0.8 0.0 0.1 0.2 7.0 8.0 4.6 6.6 0.0 0.5 0.5 1.3 0.8 0.1 0.0 1.3 0.0 0.0 1.8 3.0 0.8 1.5 1.8 1.2 1.1 0.4 1.0 0.6 37.3 7.9 0.5 8.6 5.1 2.2 0.0 1.3 1.1 1.2 1.0 11.9 1.6 1.3 0.6 2.0 0.7 6.3 0.7 1.0 1.5 0.8 0.6 9.7 5.5 11.4 5.9 7.4 5.8 10.1 6.4 6.3 6.7 8.2 6.5 7.4 5.5 6.6 6.3 16.6 10.7 20.5 1.8 1.3 0.0 10.1 2.7 0.9 1.5 6.9 1.9 0.0 2.6 5.2 0.5 0.0 8.2 5.5 0.0 30.7 2.9 5.5 48.3 0.1 1.8 1.3 1.6 10.0 7.3 3.7 2.1 0.1 0.0 4.8 0.0 0.1 9.7 0.1 1.2 1.9 4.2 0.0 186.8 5.4 0.0 20.6 1.1 0.0 0.0 16.2 8.2 11.7 0.2 13.5 6.4 11.5 2.0 1.6 5.6 6.2 5.3 0.4 3.6 288.6 0.0 27.7 0.0 5.5 4.6 1.3 18.5 0.7 0.6 2.3 8.6 3.8 11.3 1.3 0.0 25.5 1.7 2.4 1.4 25.3 25.6 0.3 0.3 4.2 11.5 4.0 FREM1 "C9orf143, C9orf145, C9orf154, DKFZp686M16108, FLJ25461, TILRR" ENSG00000164946 "FRAS1 related extracellular matrix 1" Q5H8C1 9 14737152-14910995 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Developmental protein" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 36.4" "Group enriched" "Detected in many" 7 "Early spermatids: 73.7;Inhibitory neurons: 126.1;Late spermatids: 144.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "HEL: 163.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA 58000 "Cluster 68: Epididymis - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.13e-5)" "unprognostic (2.59e-3)" "unprognostic (2.89e-1)" "unprognostic (1.13e-1)" "unprognostic (1.97e-1)" "unprognostic (6.27e-3)" "unprognostic (2.50e-1)" "unprognostic (4.66e-3)" "unprognostic (4.43e-1)" "unprognostic (1.31e-1)" "unprognostic (3.62e-2)" "unprognostic (6.23e-2)" "unprognostic (8.95e-13)" "unprognostic (2.28e-3)" "unprognostic (8.53e-2)" "unprognostic (3.41e-2)" "unprognostic (2.86e-1)" 5.3 2.5 0.9 0.8 1.1 0.2 4.8 4.2 1.3 5.0 2.0 6.4 2.1 19.7 36.4 1.0 4.1 3.7 6.4 1.1 1.3 17.0 0.9 2.4 0.0 2.0 1.3 1.4 6.6 5.0 1.0 5.5 1.2 1.1 1.7 1.3 0.8 3.4 0.9 3.3 5.4 14.2 3.0 0.4 1.0 4.2 1.2 1.2 0.7 0.8 0.5 2.1 2.3 3.8 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 163.8 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.4 3.7 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 4.2 1.3 1.1 1.3 2.0 1.3 1.2 3.0 1.2 3.8 0.4 0.0 0.6 13.1 0.3 1.3 0.2 0.0 0.6 2.0 0.1 0.1 2.9 2.8 0.0 1.8 0.0 0.5 0.0 0.2 0.0 0.3 73.7 1.5 7.7 0.4 0.0 3.0 16.2 0.0 0.3 11.2 0.5 1.3 5.1 0.2 3.9 0.0 0.5 0.0 126.1 2.4 0.0 0.6 1.2 144.7 0.6 0.1 0.0 6.5 0.6 4.0 0.0 7.1 4.3 0.2 0.0 1.5 0.0 0.1 13.0 1.3 0.0 0.1 0.0 0.6 2.8 0.8 0.9 0.0 1.1 0.3 0.1 6.1 4.7 0.1 FRMD6 "C14orf31, EX1, MGC17921, willin" ENSG00000139926 "FERM domain containing 6" Q96NE9 14 51489100-51730727 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 160.6;Early spermatids: 219.1;Late spermatids: 473.0;Suprabasal keratinocytes: 137.5;Urothelial cells: 130.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 351.1;fHDF/TERT166: 765.6;U-138 MG: 290.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001297 Uncertain Supported Approved Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA001297: AB_1078913" "unprognostic (1.30e-1)" "unprognostic (1.09e-1)" "unprognostic (1.84e-1)" "unprognostic (2.29e-1)" "unprognostic (2.64e-2)" "unprognostic (8.05e-2)" "unprognostic (8.19e-2)" "unprognostic (3.55e-3)" "unprognostic (1.28e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (2.66e-4)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.28e-4)" "prognostic unfavorable (3.50e-4)" "unprognostic (1.18e-1)" "unprognostic (2.11e-2)" "unprognostic (1.20e-2)" 12.1 13.4 5.2 9.5 5.2 1.2 27.1 12.6 6.7 28.1 8.4 16.0 5.2 53.6 11.3 59.8 13.4 33.0 7.3 6.4 4.5 4.2 10.4 8.6 5.5 5.7 8.1 25.9 5.0 2.4 3.4 14.1 4.9 27.7 10.8 1.5 21.5 30.7 7.4 43.2 7.5 46.8 5.4 12.0 7.2 31.0 5.8 12.6 6.6 6.8 12.7 31.5 30.1 5.6 71.4 14.1 20.1 42.1 40.1 67.6 8.8 351.1 163.2 169.5 146.0 51.9 16.4 1.9 10.6 765.6 47.6 82.8 5.7 113.8 200.3 1.1 8.6 0.3 7.6 2.2 46.8 0.2 4.2 58.8 40.9 152.0 200.5 77.8 52.6 3.7 0.7 24.6 181.8 12.2 7.1 0.2 3.9 0.2 27.4 0.8 79.1 0.7 33.4 113.7 4.1 44.9 27.8 3.9 31.3 37.7 3.0 1.0 242.6 290.7 97.6 73.3 73.5 18.9 17.3 0.2 19.3 0.3 114.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.1 0.0 0.0 0.1 5.2 5.2 12.6 6.7 6.4 4.5 5.7 8.1 4.9 5.4 5.8 5.6 6.9 3.2 1.5 34.6 0.8 111.4 160.6 42.4 41.5 0.4 40.5 49.4 2.9 8.6 11.6 0.0 0.0 40.1 1.5 0.0 0.0 16.9 219.1 2.0 41.1 14.4 0.0 2.5 45.2 2.9 4.8 57.8 1.1 3.6 1.3 0.9 9.3 4.2 3.8 0.0 22.5 0.3 10.2 0.3 21.1 473.0 17.7 1.5 32.0 68.4 0.7 8.2 0.0 74.9 5.9 64.0 0.0 22.2 3.7 52.0 0.1 0.4 2.7 0.5 6.6 24.5 28.0 10.2 9.8 115.7 137.5 39.0 3.3 0.9 0.1 130.7 FRZB "FRE, FRITZ, FRP-3, FRZB-1, FRZB-PEN, FRZB1, FZRB, hFIZ, SFRP3, SRFP3" ENSG00000162998 "Frizzled related protein" Q92765 2 182833275-182866637 "Disease related genes, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 336.9" "Cell type enriched" "Detected in many" 13 "Muller glia cells: 3633.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 19.2;ASC diff: 9.4;NTERA-2: 7.4;SH-SY5Y: 6.5" "Region enhanced" "Detected in all" "olfactory bulb: 56.9" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA 44000 "Cluster 19: B-cells - Humoral immune response" "Cluster 79: Retina - Phototransduction" "Cluster 12: NES - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (5.39e-2)" "unprognostic (1.48e-2)" "unprognostic (1.18e-1)" "unprognostic (1.79e-2)" "unprognostic (1.93e-1)" "unprognostic (2.09e-3)" "unprognostic (1.64e-2)" "unprognostic (2.38e-2)" "unprognostic (4.67e-2)" "unprognostic (8.58e-2)" "unprognostic (5.41e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (8.97e-6)" "unprognostic (3.53e-2)" "unprognostic (1.05e-2)" "unprognostic (6.04e-2)" "unprognostic (3.21e-1)" 10.4 5.7 10.4 6.1 12.8 0.7 12.6 11.0 18.6 20.3 52.2 16.2 14.4 17.2 11.4 12.4 7.1 39.0 19.9 10.3 11.2 16.3 3.3 9.1 18.7 14.1 10.9 13.5 7.1 6.7 18.6 30.5 15.4 12.9 19.9 336.9 4.7 16.6 26.6 10.4 14.5 31.1 11.9 88.9 21.9 14.2 11.3 4.9 10.8 116.2 11.9 10.3 12.3 10.3 0.0 0.0 19.2 0.2 9.4 0.2 0.2 0.0 0.9 3.2 2.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.4 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.8 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 7.4 0.0 0.0 0.6 0.8 0.0 0.0 0.0 1.0 6.5 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 12.8 11.0 18.6 10.3 11.2 14.1 10.9 15.4 11.9 11.3 10.3 13.8 0.0 0.5 1.0 0.8 8.2 0.4 0.2 0.6 39.8 7.8 18.7 2.9 0.0 1.4 0.0 33.3 5.3 0.5 2.1 0.0 0.1 0.3 0.5 1.4 18.5 1.2 0.0 2.7 8.2 3.8 97.8 9.7 0.9 0.0 0.5 3.6 1.0 7.8 26.9 7.7 137.4 0.0 0.8 3.7 2.8 3.7 0.5 245.5 25.3 0.0 3633.8 0.0 8.5 1.7 0.2 0.8 14.7 5.8 1.8 1.3 0.2 0.2 124.4 276.1 41.9 157.1 0.2 0.1 0.6 3.1 12.4 1.5 22.9 3.4 0.6 FST FS ENSG00000134363 Follistatin P19883 5 53480626-53487134 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 68.7" "Cell type enriched" "Detected in many" 6 "Granulosa cells: 700.1" "Cancer enhanced" "Detected in all" "liver cancer: 45.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 351.1;HaCaT: 292.3;HBEC3-KT: 191.3;HMC-1: 206.5;PC-3: 558.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA016612, CAB026025" Approved Approved Vesicles "Secreted to blood" NA NA 1800000 "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Vesicles "CAB026025: , HPA016612: " "unprognostic (1.43e-1)" "unprognostic (6.50e-2)" "unprognostic (1.44e-1)" "unprognostic (7.73e-3)" "unprognostic (2.30e-1)" "unprognostic (1.50e-3)" "unprognostic (8.02e-2)" "unprognostic (2.32e-2)" "unprognostic (3.06e-1)" "unprognostic (1.57e-1)" "unprognostic (1.93e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (4.44e-5)" "unprognostic (1.21e-3)" "unprognostic (2.48e-1)" "unprognostic (2.07e-2)" "unprognostic (2.18e-1)" 26.1 6.2 0.8 3.0 0.5 0.4 15.2 0.4 0.7 7.7 0.7 9.8 1.8 4.2 3.7 6.5 11.8 7.2 9.4 2.0 2.0 2.9 68.7 8.2 1.6 1.8 1.0 9.9 2.6 0.5 5.9 24.1 0.9 15.5 3.0 0.3 11.3 10.8 9.2 18.0 8.8 4.7 0.5 0.3 11.1 5.0 1.1 2.3 4.0 7.7 12.9 40.4 7.5 0.7 20.0 1.8 33.7 0.0 38.6 13.5 55.4 76.3 351.1 46.4 45.4 0.3 0.2 0.0 0.6 19.9 2.3 292.3 0.0 191.3 32.7 0.8 0.2 4.0 1.7 31.3 20.4 0.3 206.5 31.0 0.5 84.5 55.0 31.3 40.0 0.0 0.0 0.6 29.7 0.1 0.1 1.6 52.1 0.0 558.2 4.2 43.6 0.0 0.0 31.9 0.5 0.1 3.1 0.2 2.0 83.9 0.3 0.3 0.2 124.1 35.3 13.2 11.1 0.4 0.1 0.1 14.8 4.1 116.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.5 0.4 0.7 2.0 2.0 1.8 1.0 0.9 0.5 1.1 0.7 5.2 0.0 1.1 0.0 1.0 20.0 31.5 64.4 13.1 0.0 0.9 23.4 11.4 0.0 8.3 0.0 0.0 0.6 0.0 0.0 0.0 1.6 0.4 0.1 3.4 2.9 0.0 0.0 0.1 4.6 14.8 107.7 3.6 0.1 0.0 700.1 1.1 57.2 1.8 0.0 0.7 0.0 2.0 0.8 16.4 1.5 3.1 1.5 5.4 0.0 0.0 0.0 0.0 0.0 0.0 16.6 0.0 11.3 0.2 37.1 0.0 0.1 1.6 0.0 13.1 29.6 33.3 0.3 12.2 4.0 4.7 6.0 2.0 0.3 0.0 51.8 FXYD6 ENSG00000137726 "FXYD domain containing ion transport regulator 6" Q9H0Q3 11 117836976-117877486 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" Schizophrenia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 163.9;Leydig cells: 237.9;Muller glia cells: 128.7;Peritubular cells: 363.8;Sertoli cells: 355.0;Theca cells: 141.8" "Cancer enriched" "Detected in all" 6 "glioma: 71.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "classical monocyte: 37.7" "Lineage enriched" "Detected in many" 6 "monocytes: 37.7" "Cell line enhanced" "Detected in some" "AF22: 136.0;HAP1: 92.9;RH-30: 57.1;SCLC-21H: 204.5;SH-SY5Y: 114.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041334, HPA042284" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA041334: AB_10970752, HPA042284: AB_2677931" "unprognostic (2.18e-3)" "unprognostic (2.70e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (1.05e-5)" "unprognostic (3.31e-2)" "unprognostic (1.15e-1)" "prognostic favorable (5.87e-4)" "unprognostic (4.51e-2)" "unprognostic (3.78e-2)" "unprognostic (1.07e-2)" "prognostic favorable (5.97e-4)" "unprognostic (3.44e-2)" "prognostic favorable (4.38e-5)" "unprognostic (4.64e-2)" "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.60e-4)" 58.4 116.3 230.8 30.1 258.5 9.8 39.5 82.5 293.2 112.3 28.1 371.1 22.2 321.5 61.0 29.8 181.6 93.1 117.1 244.3 187.3 70.6 32.8 86.6 30.0 91.8 173.6 281.1 30.1 9.8 175.0 16.7 149.5 107.8 35.9 47.1 29.5 73.2 37.3 22.2 104.6 197.6 71.4 151.9 98.9 86.6 136.4 31.2 66.5 78.3 18.9 202.9 80.4 179.3 0.3 0.9 136.0 2.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.6 0.1 4.8 0.7 92.9 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.3 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 2.2 0.2 2.6 0.0 1.7 6.3 0.5 27.2 0.0 0.0 0.1 57.1 1.0 3.5 0.1 204.5 114.0 0.0 0.5 5.1 36.9 2.4 2.4 0.0 0.0 30.0 0.5 0.0 0.4 0.3 0.1 1.0 0.4 0.4 0.0 37.7 0.0 0.0 9.4 0.6 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.9 0.0 0.1 0.6 0.0 9.9 230.8 258.5 82.5 293.2 244.3 187.3 91.8 173.6 149.5 71.4 136.4 179.3 72.2 6.4 2.2 0.0 1.1 6.6 2.4 1.1 0.6 3.5 2.1 21.5 9.3 1.5 0.7 0.0 2.1 0.8 1.0 0.0 1.9 6.4 3.6 0.6 23.9 71.8 12.5 10.7 0.0 0.4 1.1 78.6 0.5 1.0 0.0 29.7 163.9 1.6 72.7 1.7 0.0 0.2 6.1 32.4 9.6 14.3 237.9 18.7 16.0 0.0 9.8 128.7 1.0 0.0 0.0 0.4 0.0 363.8 1.2 4.9 0.0 0.1 1.7 4.4 355.0 49.6 79.6 4.6 3.5 1.4 3.8 1.4 1.4 141.8 0.0 1.7 GAL3ST4 FLJ12116 ENSG00000197093 "Galactose-3-O-sulfotransferase 4" Q96RP7 7 100159244-100168617 "Metabolic proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 27.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 37.2;Microglial cells: 23.4;Oligodendrocyte precursor cells: 24.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 4.5;naive CD4 T-cell: 15.0;naive CD8 T-cell: 4.6;plasmacytoid DC: 4.7" "Group enriched" "Detected in many" 29 "dendritic cells: 4.7;T-cells: 15.0" "Cell line enhanced" "Detected in many" "WM-115: 43.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038137, HPA038138" Uncertain Approved Nucleoplasm,Cytosol NA NA 35000 "Cluster 32: T-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm Cytosol "HPA038137: AB_10697239, HPA038138: AB_2675854" "unprognostic (4.22e-2)" "unprognostic (2.97e-2)" "prognostic unfavorable (5.44e-4)" "unprognostic (8.64e-2)" "unprognostic (3.01e-2)" "unprognostic (1.40e-1)" "unprognostic (3.10e-2)" "unprognostic (1.81e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.57e-4)" "unprognostic (2.80e-1)" "unprognostic (2.25e-1)" "prognostic unfavorable (4.14e-4)" "unprognostic (3.98e-2)" "unprognostic (9.67e-2)" "unprognostic (1.89e-2)" "unprognostic (5.36e-2)" 4.3 4.9 9.2 3.9 9.3 0.7 3.7 8.4 12.6 11.0 7.6 6.1 3.8 9.1 3.1 7.8 6.0 5.6 5.0 9.1 9.5 1.4 0.9 5.2 2.9 13.4 9.5 6.3 1.4 3.0 4.2 5.1 10.1 4.8 6.3 0.5 25.6 3.6 1.9 27.7 5.0 9.9 10.7 2.7 2.4 4.8 15.9 22.3 1.9 1.9 3.2 6.7 10.6 13.1 0.1 0.9 5.4 2.3 4.7 9.6 10.9 3.2 3.2 1.8 2.6 0.6 0.2 1.1 0.7 10.4 3.3 12.2 0.3 1.8 0.6 0.1 0.6 0.4 0.2 0.4 3.4 0.3 2.7 11.7 4.6 5.5 0.6 4.0 3.7 4.3 1.6 0.2 3.4 0.4 4.2 0.2 1.9 11.5 1.3 2.7 2.4 0.2 0.0 0.4 0.3 2.2 1.0 0.0 6.7 1.0 0.0 0.3 3.4 0.3 1.6 0.5 0.1 0.2 0.2 2.5 1.9 0.4 43.3 0.0 0.1 0.0 0.5 0.0 0.0 0.1 4.5 0.3 0.0 0.1 15.0 4.6 0.3 0.2 0.1 4.7 1.3 2.2 9.2 9.3 8.4 12.6 9.1 9.5 13.4 9.5 10.1 10.7 15.9 13.1 0.7 0.0 0.5 2.9 0.1 4.2 2.0 3.3 7.4 0.0 2.2 2.4 1.0 1.5 0.9 0.0 0.0 0.3 0.3 1.5 0.0 0.6 0.2 0.2 2.1 1.2 0.0 2.7 0.5 0.0 0.4 7.5 0.0 0.3 0.0 1.2 1.4 0.0 37.2 0.0 0.3 1.3 4.1 1.3 0.8 0.0 4.7 9.6 5.4 23.4 0.7 0.4 0.0 24.6 0.5 0.3 2.5 5.3 0.0 0.5 0.0 0.0 0.1 0.1 0.0 3.7 3.3 0.6 0.3 4.2 8.1 0.8 0.7 0.1 4.1 1.4 GALNT12 GalNAc-T12 ENSG00000119514 "Polypeptide N-acetylgalactosaminyltransferase 12" Q8IXK2 9 98807670-98850081 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 74.7;intestine: 55.8;stomach 1: 54.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 101.2;Intestinal goblet cells: 142.4;Undifferentiated cells: 42.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 128.4;U-2197: 160.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA048292, HPA071076" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 47000 "Cluster 48: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA048292: AB_2680343, HPA071076: " "unprognostic (7.85e-3)" "unprognostic (1.50e-1)" "unprognostic (2.33e-1)" "unprognostic (1.47e-2)" "unprognostic (2.97e-3)" "unprognostic (4.10e-2)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (2.03e-2)" "unprognostic (1.97e-1)" "unprognostic (2.61e-2)" "unprognostic (7.71e-2)" "prognostic favorable (3.24e-4)" "unprognostic (9.05e-2)" "unprognostic (1.92e-1)" "unprognostic (1.60e-3)" "unprognostic (6.87e-2)" 5.0 2.0 1.2 7.7 1.3 2.2 3.4 6.5 1.8 8.7 4.3 55.3 34.2 3.7 74.7 19.6 7.5 10.5 1.2 1.1 1.4 4.8 0.4 11.7 3.2 2.6 1.4 0.4 13.6 6.3 3.4 2.6 2.7 4.6 55.8 0.6 25.5 4.3 1.3 3.4 27.1 14.0 1.1 2.2 54.8 4.6 1.5 3.3 14.7 0.6 6.1 11.9 4.6 1.6 5.4 4.1 3.4 13.5 10.0 7.8 0.0 1.4 2.1 2.0 4.6 0.8 21.6 0.0 5.0 0.9 12.2 38.0 2.9 1.3 1.6 26.2 1.7 2.4 0.2 0.0 0.5 1.6 0.5 3.8 0.9 6.4 0.0 2.7 2.3 19.3 30.2 0.0 0.6 13.9 2.6 4.7 16.7 128.4 5.6 6.5 0.3 0.1 2.3 7.7 12.4 1.1 0.5 30.6 3.0 7.7 4.5 4.5 4.3 0.0 0.3 160.9 0.0 2.1 4.8 2.3 37.1 0.0 0.9 0.0 0.0 0.5 0.3 0.0 0.6 0.0 0.4 0.2 0.0 0.1 0.6 0.3 0.0 0.6 0.0 0.1 0.0 0.1 1.2 1.3 6.5 1.8 1.1 1.4 2.6 1.4 2.7 1.1 1.5 1.6 1.3 3.2 25.7 2.0 2.3 2.4 1.3 8.3 1.2 2.4 0.4 0.1 1.0 18.6 16.9 11.0 16.7 1.0 2.6 101.2 0.0 11.2 1.8 4.8 1.6 1.6 19.9 1.3 7.4 25.4 1.7 12.5 32.1 8.7 2.5 2.4 0.0 0.0 2.3 0.0 5.7 142.4 2.0 0.3 3.9 1.4 2.1 3.9 0.0 3.7 0.2 0.8 3.1 3.5 7.0 32.0 36.5 7.5 1.7 7.4 21.9 2.7 16.9 0.2 0.0 0.7 1.5 5.9 10.5 9.9 1.3 1.1 4.5 5.1 42.5 11.1 GALNT5 GalNAc-T5 ENSG00000136542 "Polypeptide N-acetylgalactosaminyltransferase 5" Q7Z7M9 2 157257705-157318491 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.5;lung: 10.2;stomach 1: 12.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 157.0;Distal enterocytes: 48.3;Intestinal goblet cells: 75.5;Pancreatic endocrine cells: 53.5;Prostatic glandular cells: 40.1;Urothelial cells: 115.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 9 "cerebellum: 4.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 45.3;BJ: 29.8;BJ hTERT+: 53.5;fHDF/TERT166: 64.5;HaCaT: 51.8;K-562: 30.7;LHCN-M2: 52.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA008963, HPA009035" Approved Approved "Nucleoli,Golgi apparatus,Vesicles,Cytosol" NA NA 1300000 "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus, Cytosol" "Nucleoli, Vesicles" "HPA008963: AB_1078942, HPA009035: AB_1078943" "unprognostic (6.34e-3)" "unprognostic (9.31e-2)" "unprognostic (2.11e-2)" "unprognostic (9.89e-2)" "unprognostic (3.19e-2)" "unprognostic (2.46e-2)" "unprognostic (4.63e-3)" "unprognostic (1.88e-1)" "unprognostic (1.09e-1)" "unprognostic (6.93e-2)" "unprognostic (4.01e-3)" "unprognostic (1.78e-1)" "unprognostic (1.15e-2)" "unprognostic (6.27e-2)" "unprognostic (1.29e-1)" "unprognostic (1.88e-1)" "unprognostic (9.48e-3)" 0.1 0.0 0.0 0.7 0.0 0.6 1.1 4.0 0.3 1.1 5.2 10.6 2.2 0.1 0.1 4.5 0.0 2.7 0.4 0.4 0.0 0.0 0.0 10.2 0.0 0.1 0.1 0.1 0.0 0.1 0.6 0.0 0.2 0.7 13.5 0.1 8.2 0.1 0.0 0.3 4.1 0.4 0.0 0.1 12.8 0.1 0.1 0.1 0.1 0.1 1.7 4.5 4.6 0.2 45.3 4.8 0.0 0.0 2.0 17.0 0.0 29.8 53.5 0.5 1.1 1.9 24.4 0.0 0.1 64.5 0.0 51.8 0.9 10.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.0 0.2 0.0 0.9 0.0 0.0 0.0 30.7 0.0 52.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.1 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 25.4 0.3 0.6 0.1 0.0 0.1 0.0 4.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.3 0.4 0.0 0.1 0.1 0.2 0.0 0.1 0.2 0.1 157.0 36.1 0.0 0.1 0.8 13.3 20.2 6.2 0.0 0.5 2.8 0.5 2.8 32.9 0.0 0.0 0.0 0.2 48.3 0.0 1.2 6.9 1.2 0.0 0.6 2.4 5.2 0.8 3.2 0.0 2.1 35.7 2.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 75.5 6.1 0.0 0.7 0.5 0.0 0.3 3.6 0.0 1.6 0.0 0.0 0.0 0.1 53.5 26.4 0.0 1.4 40.1 3.1 0.2 10.0 0.0 0.0 0.5 1.2 2.6 0.5 4.5 0.1 0.0 0.3 0.0 22.7 115.1 GAP43 "B-50, GAP-43, PP46" ENSG00000172020 "Growth associated protein 43" P17677 3 115623510-115721490 "Plasma proteins, Predicted intracellular proteins, Transporters" "Differentiation, Growth regulation, Neurogenesis" "Calmodulin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "brain: 277.0" "Cell type enriched" "Detected in some" 4 "Excitatory neurons: 270.2" "Cancer enriched" "Detected in many" 43 "glioma: 245.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 37.9;NTERA-2: 81.1;SCLC-21H: 52.2;SH-SY5Y: 39.6;U-87 MG: 18.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004417, HPA013392, HPA015600, CAB078783" Enhanced Supported Enhanced "Plasma membrane" NA NA 35000 "Cluster 32: T-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "CAB004417: AB_627660, CAB078783: AB_2620096, HPA013392: AB_1849468, HPA015600: AB_1849466" "unprognostic (1.24e-1)" "unprognostic (1.31e-1)" "unprognostic (1.15e-2)" "unprognostic (5.72e-5)" "unprognostic (7.44e-3)" "unprognostic (2.19e-2)" "unprognostic (3.97e-3)" "unprognostic (3.15e-3)" "unprognostic (6.08e-4)" "unprognostic (3.33e-1)" "unprognostic (2.17e-2)" "unprognostic (1.62e-1)" "unprognostic (5.35e-8)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "unprognostic (2.78e-2)" "unprognostic (1.29e-3)" 0.6 6.3 131.6 7.5 149.2 0.0 0.9 36.3 277.0 0.6 0.0 10.5 2.5 0.2 0.1 1.1 0.2 4.7 4.3 149.9 187.2 0.2 0.2 0.3 0.2 55.6 156.5 0.2 0.8 0.0 10.0 1.7 113.3 0.9 4.8 8.0 2.1 0.3 0.3 0.5 5.5 4.3 28.5 0.0 2.9 0.4 150.7 0.1 0.2 0.6 0.4 1.3 1.9 121.0 0.0 0.0 37.9 0.0 0.0 0.0 0.0 0.9 0.7 0.0 0.2 0.0 0.1 0.0 0.0 0.4 0.2 0.1 0.4 0.0 0.0 0.1 0.2 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.0 8.6 0.0 0.5 0.0 0.0 0.0 9.1 0.2 0.0 0.0 0.0 81.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.2 39.6 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 1.5 0.1 0.1 0.1 0.0 0.0 18.9 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 131.6 149.2 36.3 277.0 149.9 187.2 55.6 156.5 113.3 28.5 150.7 121.0 0.1 0.0 0.0 20.9 0.0 0.3 0.0 0.0 0.0 3.7 0.0 0.0 0.5 0.0 0.0 0.0 2.1 0.1 0.4 0.0 0.0 0.0 1.0 0.0 0.8 5.1 0.0 0.0 270.2 0.0 0.1 4.5 0.0 0.0 0.0 1.5 0.0 0.0 0.8 0.0 62.5 0.0 0.0 0.0 1.2 1.8 0.0 0.0 1.8 29.0 0.0 1.4 0.0 40.2 20.2 0.8 0.0 0.0 0.4 0.0 0.0 0.2 0.0 3.5 0.0 2.0 1.1 0.9 1.7 0.0 0.1 0.0 0.1 0.3 0.0 0.0 GAREM2 "FAM59B, FLJ00375, GAREML, KIAA2038" ENSG00000157833 "GRB2 associated regulator of MAPK1 subtype 2" Q75VX8 2 26173088-26189663 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 37.2;choroid plexus: 10.4;parathyroid gland: 22.9" "Group enriched" "Detected in many" 4 "Distal tubular cells: 46.9;Muller glia cells: 19.5;Proximal tubular cells: 42.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 16.8;SH-SY5Y: 10.2;U-2 OS: 13.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071575 Approved Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA071575: AB_2686420" "unprognostic (1.70e-2)" "unprognostic (5.62e-2)" "unprognostic (7.61e-4)" "unprognostic (1.56e-2)" "unprognostic (8.27e-2)" "unprognostic (2.19e-1)" "unprognostic (2.90e-2)" "unprognostic (1.99e-1)" "unprognostic (2.12e-2)" "unprognostic (2.65e-1)" "unprognostic (1.33e-1)" "unprognostic (3.94e-2)" "unprognostic (1.15e-3)" "unprognostic (1.35e-1)" "unprognostic (3.22e-1)" "unprognostic (1.46e-2)" "unprognostic (1.04e-1)" 2.2 0.8 27.1 1.1 30.8 0.4 1.9 30.1 22.5 2.3 10.4 3.3 0.6 3.2 0.9 1.5 2.5 1.7 3.0 21.3 26.2 2.0 0.2 1.0 1.5 32.9 32.0 3.6 2.9 22.9 2.3 0.8 27.7 1.8 1.8 3.3 1.4 2.1 2.7 1.4 1.6 2.3 27.0 1.4 2.0 2.6 37.2 0.6 1.7 2.5 1.2 2.7 2.1 23.5 3.0 4.4 5.2 0.4 0.9 1.8 0.4 1.6 0.0 0.5 0.4 8.5 1.0 0.0 2.1 3.4 5.3 0.1 16.8 0.0 0.7 1.9 6.2 1.5 1.5 0.5 6.2 0.1 0.3 2.5 0.8 2.5 0.2 0.3 2.0 4.1 8.1 0.1 3.1 0.0 0.4 0.6 5.6 0.5 1.2 1.7 0.0 0.1 2.7 0.9 1.1 10.2 3.7 0.4 3.2 1.5 0.2 9.0 0.9 2.3 13.8 4.1 0.1 0.3 0.0 1.9 0.1 0.0 3.0 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.3 0.2 0.1 0.1 0.2 0.1 0.2 0.0 0.1 0.5 0.0 0.0 27.1 30.8 30.1 22.5 21.3 26.2 32.9 32.0 27.7 27.0 37.2 23.5 1.2 0.0 0.0 0.0 1.8 0.0 0.4 0.0 0.0 1.0 0.5 0.9 0.0 1.5 0.0 3.7 2.1 0.4 1.2 1.3 46.9 2.2 4.4 0.5 2.2 1.7 0.0 0.4 0.0 1.6 2.6 3.8 3.6 0.5 0.0 0.8 0.4 0.0 0.6 0.0 0.0 0.7 0.0 0.3 0.0 7.6 2.1 1.1 0.0 0.0 0.6 19.5 2.1 0.0 0.0 1.6 1.2 3.4 0.1 1.1 0.1 42.1 0.0 1.2 6.6 1.6 1.7 1.9 6.2 0.1 0.0 0.3 2.3 0.4 1.5 0.3 GDF6 "BMP13, KFS, KFS1, SGM1" ENSG00000156466 "Growth differentiation factor 6" Q6KF10 8 96142333-96160806 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Cytokine, Developmental protein, Growth factor" "Disease variant, Dwarfism, Leber congenital amaurosis, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 10.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.3;Distal tubular cells: 1.9;Excitatory neurons: 1.6;Fibroblasts: 3.1;Oligodendrocyte precursor cells: 7.1;Spermatogonia: 2.4" "Cancer enhanced" "Detected in some" "renal cancer: 2.8;thyroid cancer: 2.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTERT-RPE1: 20.4;LHCN-M2: 33.1;SuSa: 15.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "midbrain: 1.2" HPA045206 Uncertain Supported "Nucleoplasm,Nuclear membrane,Vesicles" "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Nuclear membrane" "HPA045206: AB_10962508" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.83e-2)" "unprognostic (9.66e-9)" "unprognostic (6.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-3)" "unprognostic (5.37e-2)" "unprognostic (8.13e-3)" "prognostic unfavorable (2.17e-4)" "unprognostic (5.88e-4)" "unprognostic (1.88e-2)" "unprognostic (2.68e-2)" "unprognostic (1.71e-1)" 1.3 0.1 0.3 0.9 0.3 0.0 0.4 0.4 0.8 0.2 0.0 0.7 0.3 1.4 0.4 0.4 0.5 2.4 2.8 0.3 0.4 0.2 0.4 0.2 0.1 0.8 0.4 0.1 0.7 0.1 0.1 10.9 1.0 0.3 0.3 0.0 0.0 1.4 0.0 0.0 0.9 1.1 0.4 0.0 0.6 0.6 0.8 0.1 0.6 0.0 0.0 0.8 0.9 0.4 0.0 0.0 0.2 0.0 1.1 0.6 3.9 2.6 0.0 2.3 2.0 0.0 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.0 3.2 0.0 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.1 0.0 3.0 0.0 20.4 0.2 0.0 0.0 0.0 33.1 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.8 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.4 0.8 0.3 0.4 0.8 0.4 1.0 0.4 0.8 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.8 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 1.0 2.4 0.0 0.0 0.3 0.1 0.0 0.0 0.1 GJC2 "CX46.6, CX47, GJA12, SPG44" ENSG00000198835 "Gap junction protein gamma 2" Q5T442 1 228149930-228159826 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 51.3" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 12.5;Oligodendrocytes: 26.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 5.4;SCLC-21H: 2.9;TIME: 2.7" "Region enhanced" "Detected in all" "white matter: 105.5" "Low region specificity" "Detected in all" HPA069619 Supported "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "HPA069619: " "unprognostic (2.67e-1)" "unprognostic (1.81e-2)" "unprognostic (6.42e-2)" "unprognostic (8.19e-3)" "unprognostic (4.24e-1)" "unprognostic (1.57e-1)" "unprognostic (6.94e-2)" "unprognostic (2.56e-1)" "unprognostic (4.99e-2)" "unprognostic (7.09e-2)" "unprognostic (7.88e-3)" "unprognostic (9.67e-2)" "unprognostic (6.09e-3)" "unprognostic (2.53e-2)" "unprognostic (7.36e-2)" "unprognostic (1.54e-1)" "unprognostic (2.02e-1)" 2.9 0.9 13.6 0.6 31.2 0.2 1.7 39.0 20.2 4.2 5.2 5.8 0.2 4.7 0.9 1.4 5.4 0.7 1.7 13.9 19.5 1.3 0.5 2.9 0.6 43.9 31.6 3.8 0.5 0.7 1.4 0.5 38.1 3.0 0.3 0.5 0.8 1.7 0.8 1.7 1.7 1.8 28.1 1.4 2.4 1.2 27.6 0.4 2.0 0.8 0.3 4.2 3.5 51.3 0.2 0.2 0.1 0.3 0.8 0.4 1.0 0.8 0.2 0.3 0.4 0.5 0.7 0.1 5.4 1.5 0.4 0.5 0.2 0.2 0.1 0.2 0.9 0.2 1.4 1.2 1.4 0.0 0.0 0.2 0.1 0.5 0.3 0.7 0.1 1.0 0.6 0.1 0.2 0.3 1.1 0.3 0.3 0.0 1.1 0.2 0.1 0.0 0.4 0.0 2.9 1.7 0.2 0.0 0.2 0.1 0.1 0.2 2.7 0.7 2.1 2.5 0.9 0.1 0.4 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.6 31.2 39.0 20.2 13.9 19.5 43.9 31.6 38.1 28.1 27.6 51.3 2.8 0.0 0.6 0.7 0.2 3.4 1.3 0.6 1.8 2.6 1.3 0.6 1.8 0.0 0.0 0.0 12.5 0.0 0.4 0.2 0.0 0.1 0.2 1.0 1.1 4.3 0.0 0.0 0.8 0.5 0.0 2.2 0.0 1.6 0.0 0.3 3.6 0.0 0.1 3.3 1.1 0.3 0.0 0.6 3.8 0.0 2.5 1.3 1.8 0.0 0.0 0.3 0.0 0.0 26.9 1.1 0.0 4.1 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.6 1.8 0.0 0.0 0.5 1.7 0.0 0.8 0.6 0.3 1.0 GLIS1 FLJ36155 ENSG00000174332 "GLIS family zinc finger 1" Q8NBF1 1 53506237-53738106 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 8.1;seminal vesicle: 7.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.6;Excitatory neurons: 28.0;Inhibitory neurons: 13.3;Proximal tubular cells: 4.8" "Cancer enhanced" "Detected in some" "renal cancer: 4.0" "Region enhanced" "Detected in some" "cerebral cortex: 2.2;hippocampal formation: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 4.5;GAMG: 5.9;hTERT-RPE1: 4.7;PC-3: 7.3;U-138 MG: 5.1" "Not detected" "Not detected" HPA001409 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Mitochondria, Cytosol" "HPA001409: AB_1078974" "unprognostic (1.30e-1)" "unprognostic (1.46e-1)" "unprognostic (2.07e-1)" "unprognostic (5.31e-2)" "unprognostic (3.67e-2)" "unprognostic (1.54e-2)" "unprognostic (8.91e-3)" "unprognostic (1.92e-1)" "unprognostic (2.27e-3)" "unprognostic (2.30e-1)" "unprognostic (3.03e-2)" "unprognostic (1.15e-2)" "unprognostic (1.93e-1)" "unprognostic (4.06e-2)" "unprognostic (1.55e-1)" "unprognostic (6.37e-4)" "unprognostic (1.98e-4)" 1.0 0.1 0.5 0.4 0.5 0.0 1.2 0.2 2.2 5.1 0.0 0.3 0.3 0.9 0.5 0.8 0.8 0.6 1.0 2.2 0.0 4.3 0.0 0.2 0.1 0.1 0.1 0.6 0.0 0.1 0.1 0.0 0.0 8.1 0.0 0.0 0.8 7.6 0.1 2.0 0.6 0.2 0.1 0.2 0.8 2.3 0.0 0.2 0.4 0.0 0.0 2.6 4.6 0.3 0.0 0.0 0.0 0.4 2.8 3.7 0.0 2.0 4.5 1.7 1.3 0.0 0.0 0.0 0.1 2.1 5.9 0.0 0.0 0.0 0.5 0.0 1.3 0.0 1.4 0.1 1.0 0.0 0.0 2.5 0.2 2.1 2.0 4.7 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 7.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.9 0.1 1.3 0.0 0.0 3.1 0.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.2 2.2 2.2 0.0 0.1 0.1 0.0 0.1 0.0 0.3 0.2 0.0 0.0 1.3 0.1 6.6 0.0 0.0 4.0 1.3 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.2 0.1 0.0 0.0 28.0 0.0 0.0 3.8 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 1.0 2.9 0.3 0.0 3.6 1.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 1.2 0.1 0.1 0.0 4.8 0.0 0.0 0.0 0.4 0.8 1.8 2.8 0.3 1.7 0.1 0.1 0.1 0.0 0.1 GLIS2 NPHP7 ENSG00000126603 "GLIS family zinc finger 2" Q9BZE0 16 4314761-4339597 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Ciliopathy, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Leydig cells: 22.1;Peritubular cells: 33.8;Proximal tubular cells: 21.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-2197: 36.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062755, HPA065406" Enhanced Nucleoplasm NA NA "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA062755: , HPA065406: " "unprognostic (2.86e-1)" "unprognostic (3.27e-2)" "unprognostic (5.96e-2)" "prognostic unfavorable (1.59e-5)" "unprognostic (3.76e-1)" "unprognostic (5.15e-2)" "unprognostic (8.13e-2)" "unprognostic (6.65e-2)" "unprognostic (3.94e-1)" "unprognostic (2.37e-3)" "unprognostic (3.59e-1)" "unprognostic (2.48e-1)" "prognostic favorable (8.06e-6)" "unprognostic (1.59e-3)" "unprognostic (3.18e-2)" "unprognostic (1.24e-2)" "unprognostic (4.40e-3)" 16.3 23.4 4.4 2.5 4.1 0.1 11.4 5.2 3.9 22.3 3.3 19.2 1.5 20.9 0.7 4.9 17.3 5.6 30.9 3.1 3.8 41.5 3.2 30.6 1.6 5.6 5.6 27.5 13.2 2.3 18.9 4.4 4.3 21.7 0.4 0.7 9.8 4.0 3.0 7.1 7.4 3.3 4.4 4.5 11.9 5.3 5.5 0.2 19.4 0.4 0.5 20.2 11.4 2.5 6.1 12.3 2.0 4.8 1.5 7.2 4.3 6.1 5.3 2.3 1.6 3.2 5.1 0.0 10.8 6.0 2.2 3.7 1.2 5.6 0.1 8.9 0.3 0.0 10.9 1.9 6.9 0.0 0.9 4.1 1.2 1.9 0.9 2.6 1.9 0.1 0.5 2.0 1.3 4.0 0.0 1.2 4.6 0.7 2.2 11.7 2.6 6.7 0.4 0.0 0.9 4.6 6.1 2.9 1.7 0.6 8.2 1.0 3.2 3.2 6.0 36.8 1.9 1.4 0.9 1.5 1.4 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 4.1 5.2 3.9 3.1 3.8 5.6 5.6 4.3 4.4 5.5 2.5 4.8 16.0 9.8 8.5 0.0 5.6 5.4 8.7 1.8 10.6 3.5 2.4 5.9 15.7 5.6 12.9 4.2 0.9 0.1 0.0 19.6 11.8 0.2 1.8 9.0 6.9 0.0 0.0 2.1 8.3 0.9 18.3 0.5 2.1 0.0 2.6 6.8 0.7 0.4 6.7 3.2 0.2 2.0 0.3 6.1 0.9 22.1 0.8 3.6 5.6 1.0 10.4 0.0 4.0 1.3 10.3 0.0 33.8 0.0 5.1 0.0 21.7 3.1 7.3 0.0 8.2 14.6 0.2 3.4 0.7 2.8 1.1 0.7 0.1 0.0 2.8 GLT8D2 FLJ31494 ENSG00000120820 "Glycosyltransferase 8 domain containing 2" Q9H1C3 12 103988987-104064183 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 26.3;Early spermatids: 41.2;Fibroblasts: 55.9;Leydig cells: 55.9;Peritubular cells: 51.9;Skeletal myocytes: 25.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 69.3;BJ hTERT+: 89.4;HSkMC: 63.2;hTERT-RPE1: 51.9;RPTEC TERT1: 45.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA012740, HPA026904, HPA070791" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "HPA012740: , HPA026904: AB_1849731, HPA070791: " "unprognostic (4.02e-1)" "prognostic unfavorable (7.37e-4)" "unprognostic (9.53e-2)" "unprognostic (4.56e-2)" "unprognostic (1.92e-2)" "unprognostic (1.71e-1)" "unprognostic (4.34e-3)" "unprognostic (2.57e-1)" "unprognostic (1.25e-1)" "unprognostic (7.55e-2)" "unprognostic (5.03e-2)" "unprognostic (8.87e-2)" "prognostic unfavorable (1.58e-6)" "prognostic unfavorable (7.92e-4)" "unprognostic (7.15e-2)" "unprognostic (7.70e-3)" "unprognostic (7.03e-3)" 16.9 10.9 4.2 5.2 4.9 1.5 19.5 2.6 5.1 29.6 11.2 17.6 5.8 27.4 21.6 7.5 22.3 35.8 15.4 4.8 3.7 4.3 2.7 10.2 6.0 2.9 3.1 41.6 4.5 6.6 9.6 9.4 3.1 13.3 11.4 1.0 7.7 16.0 3.2 4.1 7.7 21.8 2.8 1.6 8.4 6.8 3.7 2.2 26.3 11.5 5.8 20.8 18.9 4.4 0.3 0.6 0.7 22.2 28.3 69.3 0.5 32.0 89.4 8.3 10.5 0.4 0.2 0.9 1.8 37.5 0.4 0.1 0.4 11.9 7.0 1.6 10.0 0.6 11.2 0.2 12.7 0.9 0.5 63.2 0.7 10.0 13.8 51.9 4.4 0.6 0.4 1.3 36.5 0.3 0.8 0.5 2.7 0.1 6.7 1.0 33.6 0.2 45.5 0.4 1.3 1.7 33.5 0.8 0.4 2.4 6.0 0.5 0.7 13.2 6.2 1.3 1.9 3.9 0.8 0.3 1.0 0.7 1.1 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.2 4.9 2.6 5.1 4.8 3.7 2.9 3.1 3.1 2.8 3.7 4.4 8.0 0.0 4.6 2.9 0.3 2.8 4.2 2.4 0.0 0.8 1.0 26.3 3.9 1.5 0.1 0.0 2.1 4.1 0.4 0.0 0.0 0.1 41.2 0.6 8.3 7.5 1.8 0.0 10.2 0.0 0.8 55.9 1.1 0.4 0.0 0.1 20.7 0.3 0.6 0.0 10.5 1.3 0.0 0.6 2.8 11.5 55.9 0.4 3.6 4.7 0.6 0.5 0.0 1.0 2.6 0.3 0.0 51.9 1.2 1.4 0.0 0.0 0.1 0.5 6.6 25.2 18.0 1.1 1.1 0.2 2.4 1.4 0.6 10.7 0.0 0.1 GPC3 "DGSX, OCI-5, SDYS, SGB, SGBS, SGBS1" ENSG00000147257 "Glypican 3" P51654 X 133535745-133985594 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "placenta: 574.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 65.1;Extravillous trophoblasts: 61.0;Fibroblasts: 404.2;Muller glia cells: 88.9;Syncytiotrophoblasts: 148.6" "Cancer enriched" "Detected in all" 4 "liver cancer: 269.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.8;naive CD8 T-cell: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.8" "Group enriched" "Detected in some" 5 "HAP1: 514.3;Hep G2: 1825.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006316 Supported "Plasma membrane" NA NA 27000 "Cluster 32: T-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane" "HPA006316: AB_1078994" "unprognostic (2.06e-1)" "unprognostic (2.36e-1)" "unprognostic (9.51e-2)" "unprognostic (4.17e-2)" "unprognostic (1.78e-1)" "unprognostic (1.46e-1)" "unprognostic (6.10e-2)" "unprognostic (1.17e-2)" "unprognostic (2.07e-2)" "unprognostic (3.92e-3)" "unprognostic (6.06e-2)" "unprognostic (1.71e-1)" "unprognostic (3.81e-3)" "prognostic unfavorable (4.83e-4)" "unprognostic (1.43e-1)" "unprognostic (2.21e-1)" "unprognostic (1.60e-1)" 99.9 22.8 0.5 3.5 1.0 0.0 61.8 0.5 0.3 11.8 0.2 6.5 1.6 9.2 41.1 6.7 13.9 13.7 24.5 0.3 4.0 87.0 5.1 122.9 2.5 1.9 3.1 15.5 21.2 4.1 47.0 574.9 3.0 8.3 4.1 6.2 13.7 9.2 4.5 18.0 5.6 7.3 1.7 3.7 13.6 2.8 2.0 8.0 22.4 28.6 10.9 14.6 9.3 1.0 0.0 0.0 21.8 1.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 154.0 0.0 0.0 0.1 0.1 0.0 0.0 514.3 0.4 0.0 0.0 22.6 0.0 0.9 1825.2 0.3 0.0 0.5 12.9 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.5 0.1 132.1 0.1 0.0 0.0 0.0 0.1 122.4 6.1 15.3 40.3 0.0 0.0 0.4 233.8 0.5 23.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.8 1.2 0.0 0.7 0.0 0.0 0.0 0.1 0.5 1.0 0.5 0.3 0.3 4.0 1.9 3.1 3.0 1.7 2.0 1.0 28.5 0.0 1.7 0.3 1.0 10.5 4.8 17.0 0.0 0.4 5.0 10.4 0.5 1.5 20.0 5.5 0.0 65.1 0.8 0.5 19.6 0.3 0.9 0.2 0.4 1.8 1.8 0.0 2.5 1.6 61.0 404.2 0.5 1.5 0.0 1.0 2.2 0.0 26.7 0.0 2.5 3.1 2.0 0.0 6.1 2.4 10.5 1.0 3.6 23.4 0.0 88.9 0.0 3.5 1.4 1.7 2.6 3.0 0.4 2.7 1.2 40.7 24.3 3.1 0.0 21.7 21.3 6.9 7.1 0.2 4.0 148.6 1.1 7.6 4.1 0.6 GPR162 "A-2, GRCA" ENSG00000250510 "G protein-coupled receptor 162" Q16538 12 6821624-6829972 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "brain: 180.3;choroid plexus: 108.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 86.3;Excitatory neurons: 36.8;Horizontal cells: 40.4;Inhibitory neurons: 32.9;Muller glia cells: 55.9;Respiratory ciliated cells: 56.2" "Cancer enriched" "Detected in many" 6 "glioma: 16.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 6.9;intermediate monocyte: 4.3;neutrophil: 17.4" "Group enriched" "Detected in many" 6 "granulocytes: 17.4;monocytes: 6.9" "Cell line enhanced" "Detected in many" "AF22: 17.7;AN3-CA: 21.1;hTERT-RPE1: 18.1;NTERA-2: 19.8;SH-SY5Y: 13.5;U-2 OS: 16.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055135 Enhanced Approved "Centriolar satellite" "Intracellular and membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Centriolar satellite" "HPA055135: AB_2682710" "unprognostic (4.76e-2)" "unprognostic (8.00e-2)" "unprognostic (8.24e-3)" "unprognostic (1.31e-2)" "unprognostic (1.31e-1)" "unprognostic (2.38e-1)" "unprognostic (4.78e-2)" "unprognostic (2.25e-2)" "unprognostic (5.83e-3)" "unprognostic (1.18e-1)" "prognostic favorable (4.29e-5)" "unprognostic (3.82e-3)" "prognostic unfavorable (1.37e-6)" "unprognostic (3.10e-3)" "unprognostic (1.77e-1)" "unprognostic (3.22e-1)" "unprognostic (3.64e-2)" 5.1 6.8 116.5 4.4 122.2 1.3 2.7 111.7 180.3 5.8 108.2 15.2 3.1 7.6 2.5 2.3 18.3 5.9 10.9 138.2 106.4 5.6 6.2 17.6 1.5 100.8 100.5 5.8 2.5 10.6 31.7 4.4 101.0 5.8 2.7 20.6 1.4 1.7 1.5 1.4 8.0 5.9 93.3 6.6 5.0 1.5 106.2 1.4 2.8 1.1 0.7 7.2 2.8 117.4 0.0 3.9 17.7 21.1 1.9 1.3 0.1 1.3 4.6 3.9 2.3 0.4 0.0 0.0 0.1 2.6 0.1 0.1 2.8 0.0 1.9 0.0 1.3 2.1 0.2 0.0 3.0 0.4 0.0 3.2 0.0 6.0 0.3 18.1 10.9 1.6 1.0 0.1 1.5 0.0 0.5 1.5 19.8 0.0 0.1 0.0 2.2 3.9 1.3 0.0 1.5 13.5 0.0 0.0 0.6 12.0 0.1 5.3 7.4 2.7 16.1 1.4 2.5 0.0 1.3 0.1 2.9 3.8 0.3 0.0 6.9 0.0 0.0 4.3 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 17.4 0.0 1.5 1.7 0.0 1.9 116.5 122.2 111.7 180.3 138.2 106.4 100.8 100.5 101.0 93.3 106.2 117.4 0.5 0.0 0.0 11.8 0.3 0.8 0.2 2.3 0.0 86.3 3.6 1.3 3.8 1.5 2.6 1.8 4.2 0.1 0.0 0.0 1.9 0.0 0.1 9.3 5.6 3.5 0.0 0.4 36.8 0.0 0.1 2.9 0.0 0.3 0.0 0.6 6.1 1.5 2.6 40.4 32.9 0.0 2.0 3.7 3.4 0.6 7.5 5.2 0.0 6.5 4.2 55.9 0.0 23.1 3.7 0.1 0.0 14.7 0.1 0.5 0.0 1.9 56.2 9.0 0.0 0.5 8.1 0.0 0.2 0.2 0.1 0.3 0.2 1.3 0.1 0.1 GPR173 SREB3 ENSG00000184194 "G protein-coupled receptor 173" Q9NS66 X 53048789-53080615 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 18.4" "Cell type enhanced" "Detected in some" "Astrocytes: 43.4;Excitatory neurons: 19.7;Inhibitory neurons: 14.1;Oligodendrocyte precursor cells: 49.3;Oligodendrocytes: 42.3" "Cancer enhanced" "Detected in many" "glioma: 8.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 3.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HAP1: 9.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003905 Approved "Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "Plasma membrane" "HPA003905: AB_1078922" "unprognostic (2.68e-1)" "unprognostic (2.33e-1)" "unprognostic (4.95e-3)" "prognostic unfavorable (2.88e-6)" "unprognostic (3.87e-2)" "unprognostic (8.58e-2)" "unprognostic (2.73e-1)" "unprognostic (1.47e-1)" "unprognostic (1.92e-1)" "unprognostic (1.70e-2)" "prognostic favorable (2.33e-5)" "unprognostic (1.03e-1)" "prognostic unfavorable (2.47e-4)" "unprognostic (1.08e-4)" "unprognostic (2.83e-1)" "unprognostic (3.92e-2)" "unprognostic (6.95e-2)" 2.2 2.7 12.6 1.4 11.7 1.0 2.0 14.5 12.5 6.6 4.6 4.2 0.6 5.5 2.1 1.0 6.4 1.4 4.0 12.3 14.2 2.9 0.4 2.6 1.0 10.9 13.6 12.0 0.8 1.1 18.4 2.1 13.3 4.0 1.1 7.0 1.3 2.3 2.4 1.7 2.1 1.9 9.3 3.3 1.9 1.5 14.5 1.5 1.8 1.0 0.4 3.2 3.6 12.0 0.0 0.0 7.8 0.8 4.1 2.4 0.3 1.4 2.7 2.0 2.3 0.8 0.1 0.2 1.9 2.6 5.9 0.8 9.5 0.0 1.7 0.9 1.3 0.6 9.3 0.3 6.0 0.5 0.2 5.8 0.0 3.0 4.1 6.6 3.2 0.2 0.0 5.4 2.9 4.6 0.2 0.1 6.2 0.4 3.5 0.2 2.6 0.7 0.4 0.4 5.8 7.9 0.0 0.8 0.0 4.7 1.2 0.2 5.7 3.4 5.0 2.6 1.1 0.2 0.7 0.8 2.5 0.0 1.8 3.3 0.1 0.2 0.4 0.1 0.2 0.2 0.2 0.1 0.0 0.4 0.2 0.2 0.6 0.8 0.2 0.3 0.1 0.0 12.6 11.7 14.5 12.5 12.3 14.2 10.9 13.6 13.3 9.3 14.5 12.0 0.5 0.0 0.0 43.4 0.2 0.3 0.4 0.6 0.0 6.6 0.1 0.3 0.8 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 5.2 1.1 3.5 0.0 19.7 0.0 0.0 1.5 0.0 0.3 0.0 7.1 1.8 0.1 0.2 6.7 14.1 0.4 0.0 0.3 0.7 0.0 3.1 0.2 1.8 11.2 0.0 3.2 0.0 49.3 42.3 0.1 0.0 4.5 0.0 0.3 0.0 0.1 0.1 3.1 0.0 2.0 2.5 0.1 0.2 0.0 0.0 0.1 0.1 2.8 0.1 0.2 GYPE "GPE, MNS" ENSG00000197465 "Glycophorin E (MNS blood group)" P15421 4 143870864-143905563 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "bone marrow: 13.3" "Cell type enriched" "Detected in some" 11 "Erythroid cells: 188.4" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.4" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.2" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 12 "HEL: 120.9;K-562: 39.8" NA NA "Cluster 37: B-cells - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "unprognostic (2.17e-1)" "unprognostic (6.03e-2)" "unprognostic (2.66e-1)" "unprognostic (1.00e-2)" "unprognostic (4.71e-2)" "unprognostic (1.09e-4)" "unprognostic (2.05e-2)" "unprognostic (1.29e-1)" "unprognostic (6.77e-2)" "unprognostic (1.10e-1)" "unprognostic (1.53e-2)" "unprognostic (2.81e-3)" "unprognostic (1.10e-4)" "unprognostic (7.81e-3)" "unprognostic (1.76e-1)" "unprognostic (2.97e-1)" "unprognostic (3.49e-2)" 1.4 0.3 0.1 1.4 0.8 13.3 0.7 0.0 1.4 0.7 0.0 0.2 0.0 0.3 0.7 0.3 0.2 0.7 1.4 0.6 0.0 0.4 0.1 2.9 1.1 0.0 0.0 0.0 0.1 0.2 0.2 0.8 0.0 0.3 0.4 0.2 0.3 0.6 0.1 0.4 0.9 0.4 0.0 3.2 0.3 0.5 0.0 1.1 0.7 0.0 2.5 0.7 0.2 0.1 0.0 0.0 0.0 0.0 6.8 6.6 0.0 2.8 6.4 1.4 1.8 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.2 0.0 1.6 0.0 0.0 120.9 0.0 0.0 1.3 0.0 0.0 0.8 0.0 0.0 0.0 1.5 0.0 0.0 39.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.9 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.8 0.0 1.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 16.0 1.5 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 1.0 0.1 0.0 188.4 5.3 0.0 0.2 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.8 0.5 0.3 0.0 0.3 3.6 1.0 0.0 0.0 1.0 6.0 1.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.8 0.3 0.0 0.0 0.1 0.3 0.7 0.0 0.0 HAAO ENSG00000162882 "3-hydroxyanthranilate 3,4-dioxygenase" P46952 2 42767089-42792593 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 295.8" "Group enriched" "Detected in many" 5 "Hepatocytes: 209.8;Proximal enterocytes: 236.8;Proximal tubular cells: 162.7" "Group enriched" "Detected in all" 5 "liver cancer: 46.5;renal cancer: 13.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 23.2" "Group enriched" "Detected in many" 5 "dendritic cells: 23.2;granulocytes: 19.2;monocytes: 17.4" "Cell line enhanced" "Detected in some" "CACO-2: 14.0;Hep G2: 49.4;REH: 9.9;THP-1: 9.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036394, HPA042024" Enhanced NA NA 580000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036394: AB_10673131, HPA042024: AB_2677803" "unprognostic (6.97e-3)" "unprognostic (1.86e-2)" "unprognostic (1.63e-2)" "unprognostic (4.44e-2)" "unprognostic (1.78e-1)" "unprognostic (7.23e-3)" "prognostic favorable (5.77e-4)" "unprognostic (6.20e-2)" "unprognostic (7.58e-2)" "unprognostic (5.10e-2)" "unprognostic (1.26e-1)" "unprognostic (2.68e-2)" "unprognostic (1.05e-1)" "unprognostic (8.67e-2)" "unprognostic (1.37e-1)" "unprognostic (2.56e-1)" "unprognostic (2.03e-1)" 8.7 5.4 1.8 5.9 2.1 4.1 12.9 2.1 2.5 16.0 3.3 13.2 23.1 10.5 14.5 6.0 10.6 6.1 7.0 1.8 2.3 41.8 295.8 5.7 6.1 2.0 2.5 14.0 26.3 2.9 4.5 8.5 2.3 10.1 11.6 0.3 3.8 11.3 2.4 5.0 40.8 4.7 2.1 5.4 9.6 1.8 2.1 4.0 5.8 3.2 4.5 15.8 9.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 4.6 14.0 0.1 0.0 0.1 0.6 0.0 0.0 4.7 0.0 0.8 0.0 1.4 5.6 0.0 49.4 0.4 1.9 0.1 2.3 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 2.6 0.2 0.0 9.9 1.1 0.3 0.0 0.0 0.1 0.0 0.6 1.0 0.0 1.3 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 7.9 17.4 19.2 0.0 10.5 0.0 3.5 0.0 0.0 23.2 3.9 0.0 0.1 5.5 0.7 2.9 7.7 0.0 5.6 1.8 2.1 2.1 2.5 1.8 2.3 2.0 2.5 2.3 2.1 2.1 2.3 2.5 0.0 1.1 3.6 3.5 4.0 6.3 2.3 14.8 0.1 2.9 7.6 0.6 14.3 1.6 1.8 0.0 1.1 2.9 18.3 17.6 7.4 0.0 0.6 8.1 1.9 6.7 12.0 3.4 13.3 0.5 18.0 1.5 0.3 30.4 1.2 4.6 209.8 21.3 0.0 2.2 14.9 0.0 13.5 4.9 0.2 12.5 8.7 5.4 8.4 8.4 3.6 1.0 5.5 1.0 4.8 28.7 10.5 0.5 2.1 236.8 162.7 0.5 0.3 13.1 37.7 13.8 0.4 0.7 6.0 4.8 1.2 1.2 2.2 25.5 2.7 HES1 "bHLHb39, FLJ20408, HES-1, HRY" ENSG00000114315 "Hes family bHLH transcription factor 1" Q14469 3 194136148-194138732 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 850.6;Muller glia cells: 1146.0;Paneth cells: 1137.2;Undifferentiated cells: 882.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "eosinophil: 15.6" "Lineage enriched" "Detected in many" 8 "granulocytes: 15.6" "Cell line enhanced" "Detected in many" "hTCEpi: 94.1;OE19: 95.8;SK-BR-3: 78.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066929 Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA066929: AB_2732753" "unprognostic (1.79e-2)" "unprognostic (2.41e-1)" "unprognostic (1.79e-2)" "unprognostic (4.44e-2)" "unprognostic (1.00e-1)" "unprognostic (1.46e-1)" "unprognostic (3.01e-2)" "unprognostic (1.05e-1)" "unprognostic (4.64e-1)" "unprognostic (2.62e-2)" "unprognostic (2.04e-2)" "unprognostic (1.40e-2)" "unprognostic (1.71e-2)" "unprognostic (1.44e-1)" "unprognostic (1.74e-1)" "unprognostic (1.85e-1)" "prognostic favorable (2.04e-5)" 64.2 32.2 13.6 7.9 14.9 0.9 87.0 12.5 15.0 66.0 11.8 44.1 31.2 22.5 9.0 127.8 22.4 17.7 65.6 14.7 16.8 87.3 68.7 47.1 7.0 15.3 17.4 25.3 34.8 22.6 42.7 27.5 13.5 90.1 35.7 66.5 79.9 31.5 69.9 184.5 23.9 9.8 13.5 23.4 42.1 12.8 14.5 11.9 93.2 22.4 11.8 59.8 136.6 11.6 9.3 2.6 20.8 27.1 6.1 0.0 5.2 4.3 12.2 0.9 0.5 36.4 26.1 1.3 74.6 1.6 12.6 51.4 3.9 24.2 0.3 7.7 44.0 33.1 3.5 9.4 0.1 0.2 30.1 2.2 94.1 0.8 10.9 14.3 28.6 1.7 16.1 1.2 0.0 43.9 47.5 45.7 19.4 95.8 17.8 0.1 1.5 1.0 28.0 71.2 1.2 1.6 21.0 78.9 38.9 23.6 22.2 2.6 22.3 2.3 21.8 0.3 31.3 0.2 0.1 0.2 1.6 0.1 43.7 0.0 0.0 15.6 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 0.0 13.6 14.9 12.5 15.0 14.7 16.8 15.3 17.4 13.5 13.5 14.5 11.6 684.0 25.6 96.0 70.2 54.2 122.9 498.5 736.7 159.4 15.9 352.0 164.1 128.8 517.6 355.1 196.8 16.7 41.1 4.7 696.8 189.8 268.9 2.2 231.9 37.6 401.8 160.1 19.2 1.2 199.1 6.0 274.1 105.0 257.4 303.4 16.1 850.6 163.1 24.4 10.1 0.4 579.7 213.6 95.3 76.2 8.7 58.7 74.6 80.0 5.6 22.8 1146.0 0.0 4.5 0.1 227.1 1137.2 18.8 5.0 231.1 297.5 126.6 190.2 54.9 164.3 76.8 291.7 1.2 13.2 367.8 296.5 209.2 24.1 31.4 882.7 358.1 HES4 bHLHb42 ENSG00000188290 "Hes family bHLH transcription factor 4" Q9HCC6 1 998962-1000172 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 345.1;Paneth cells: 397.4;Prostatic glandular cells: 286.6;Smooth muscle cells: 385.7;Urothelial cells: 494.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "eosinophil: 12.4" "Lineage enriched" "Detected in many" 10 "granulocytes: 12.4" "Cell line enriched" "Detected in many" 7 "HEK 293: 198.1" "Low region specificity" "Detected in all" HPA062465 Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "Vesicles, Cytosol" "HPA062465: AB_2684771" "unprognostic (6.23e-2)" "unprognostic (3.77e-2)" "unprognostic (7.07e-2)" "prognostic favorable (3.85e-4)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.99e-4)" "unprognostic (6.25e-3)" "unprognostic (2.34e-1)" "unprognostic (1.62e-2)" "unprognostic (3.77e-1)" "unprognostic (7.76e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (3.97e-1)" "unprognostic (3.87e-2)" "unprognostic (1.86e-1)" "unprognostic (5.08e-3)" 10.5 1.9 12.9 0.7 15.3 0.5 9.1 8.1 34.3 9.2 0.9 11.0 1.2 10.5 0.4 7.5 10.3 0.1 22.6 6.8 17.9 13.6 3.0 10.8 0.2 22.3 15.8 3.9 5.6 0.9 8.4 1.5 17.0 11.4 0.3 0.8 7.7 2.2 4.0 8.4 3.9 1.2 6.0 4.4 5.6 2.6 24.0 1.4 6.0 0.9 0.3 10.0 8.4 4.0 14.3 1.6 1.5 0.2 0.2 0.1 17.6 8.6 1.0 5.2 5.4 2.3 4.5 0.0 20.0 0.7 2.3 25.3 2.1 0.3 0.2 0.1 198.1 0.1 2.4 2.9 1.7 0.0 1.7 0.1 2.0 0.3 0.4 0.7 0.6 2.5 4.1 0.3 0.0 7.6 11.7 0.6 0.2 3.1 19.2 0.2 1.9 4.4 2.0 0.0 1.1 4.6 5.8 14.3 29.1 0.7 10.5 0.0 1.1 1.6 0.6 0.0 4.0 0.0 0.0 0.0 0.1 0.3 0.5 0.0 0.0 12.4 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 12.9 15.3 8.1 34.3 6.8 17.9 22.3 15.8 17.0 6.0 24.0 4.0 90.1 0.0 0.0 18.6 15.3 52.1 345.1 1.7 6.8 8.9 158.9 149.4 13.3 20.0 4.0 58.8 0.0 1.5 22.3 88.3 31.3 44.1 1.0 74.7 30.0 63.4 10.7 2.7 12.9 2.9 43.9 65.5 11.2 153.3 53.5 3.1 37.5 0.8 4.8 0.0 25.9 25.4 4.1 10.0 120.5 1.5 7.5 70.8 115.6 11.2 5.2 129.7 12.3 8.5 1.7 10.7 397.4 15.4 2.3 286.6 1.5 0.8 1.1 11.3 164.3 157.8 385.7 3.2 29.6 43.0 82.7 3.4 27.4 2.0 56.9 494.9 HHIPL1 KIAA1822 ENSG00000182218 "HHIP like 1" Q96JK4 14 99645129-99680569 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.7" "Cell type enhanced" "Detected in some" "Astrocytes: 33.3;Bipolar cells: 10.5;Excitatory neurons: 8.3;Inhibitory neurons: 12.2;Muller glia cells: 13.1;Oligodendrocyte precursor cells: 13.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 3.1;fHDF/TERT166: 5.6;SiHa: 3.7;THP-1: 3.9" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA 120000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (6.16e-2)" "unprognostic (3.44e-2)" "unprognostic (3.43e-2)" "unprognostic (1.59e-2)" "unprognostic (1.30e-1)" "unprognostic (2.31e-1)" "unprognostic (2.75e-2)" "unprognostic (4.70e-3)" "unprognostic (6.68e-2)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "unprognostic (1.35e-3)" "unprognostic (8.49e-6)" "unprognostic (2.52e-2)" "unprognostic (2.97e-1)" "unprognostic (2.70e-2)" "unprognostic (7.12e-6)" 1.6 0.3 7.0 1.1 8.7 0.1 0.8 4.1 8.4 1.5 3.0 2.0 0.5 2.5 0.4 0.8 1.3 1.2 1.6 7.2 4.6 0.7 0.6 0.7 1.0 4.9 4.7 1.0 0.2 0.3 0.9 0.6 4.5 1.7 0.3 2.1 0.8 0.9 0.3 0.5 0.9 1.8 4.0 0.9 0.8 0.4 6.3 0.1 0.5 0.4 0.6 1.3 1.1 4.2 0.0 0.2 0.4 0.1 0.1 0.0 1.7 1.6 0.4 0.3 0.1 0.1 0.5 0.1 3.1 5.6 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 1.7 0.0 0.0 0.9 0.1 1.2 0.2 0.1 1.4 0.1 0.0 0.1 0.9 0.2 0.0 0.2 1.2 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.1 0.6 3.7 0.0 0.0 0.6 0.0 3.9 1.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 8.7 4.1 8.4 7.2 4.6 4.9 4.7 4.5 4.0 6.3 4.2 1.6 0.0 0.0 33.3 0.1 0.0 0.0 0.0 0.0 10.5 0.3 0.8 3.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 2.0 1.7 0.0 0.0 8.3 0.0 0.1 2.6 0.0 0.0 0.0 0.9 0.7 0.3 1.9 0.0 12.2 0.0 0.0 2.1 0.7 0.2 0.3 0.3 3.6 6.5 0.0 13.1 0.0 13.0 6.2 0.0 1.4 1.9 0.0 0.1 0.1 0.0 0.0 1.7 0.0 0.9 0.9 0.3 0.4 0.0 0.0 0.1 0.0 0.7 0.0 0.1 HMCN2 "DKFZp434P0216, FLJ23816" ENSG00000148357 "Hemicentin 2" Q8NDA2 9 130265882-130434123 "Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 33.9;intestine: 51.1" "Cell type enriched" "Detected in many" 8 "Skeletal myocytes: 283.7" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "pons: 4.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 7.8;RH-30: 18.0;SCLC-21H: 2.6;SH-SY5Y: 4.1;U-138 MG: 2.9;U-87 MG: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA053903, HPA070647" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 27000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA053903: AB_2682301, HPA070647: AB_2686290" "unprognostic (1.61e-1)" "unprognostic (8.05e-3)" "unprognostic (1.69e-1)" "unprognostic (5.53e-4)" "unprognostic (1.05e-1)" "unprognostic (1.12e-2)" "unprognostic (1.10e-1)" "unprognostic (8.78e-3)" "unprognostic (3.23e-1)" "unprognostic (3.97e-4)" "unprognostic (3.36e-2)" "unprognostic (3.93e-1)" "unprognostic (1.04e-3)" "unprognostic (1.53e-2)" "unprognostic (3.62e-2)" "unprognostic (8.96e-3)" "unprognostic (8.63e-2)" 14.4 1.3 0.3 1.5 0.2 0.0 3.9 0.1 0.7 21.4 0.0 51.1 5.2 33.9 0.1 4.8 10.1 0.7 12.4 0.1 0.9 4.0 1.2 3.8 1.2 2.0 0.7 2.6 0.9 0.1 0.3 0.2 4.0 9.2 1.9 0.0 2.2 2.3 25.0 4.1 21.6 4.2 1.2 0.4 4.9 5.7 1.0 1.2 4.8 6.3 0.2 9.2 12.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.4 0.2 0.5 0.0 18.0 0.1 0.0 0.1 2.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.2 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.7 0.1 0.9 2.0 0.7 4.0 1.2 1.0 0.4 1.2 3.2 7.5 2.3 0.5 0.9 0.4 0.0 0.0 1.1 0.2 0.3 4.8 0.0 3.7 0.0 0.0 0.1 0.1 22.9 1.9 0.0 17.0 0.0 0.2 5.0 0.0 0.0 1.3 0.0 0.1 24.8 0.0 0.1 7.6 0.1 0.7 2.3 0.4 1.7 5.8 3.6 2.0 0.8 0.8 10.6 0.0 2.3 1.8 1.0 0.0 0.0 0.0 0.5 0.7 0.1 8.3 0.0 0.1 0.8 34.1 1.2 4.0 0.7 0.0 283.7 4.5 0.9 1.1 0.0 0.6 0.3 1.6 2.9 5.5 4.7 HOXB2 "HOX2, HOX2H" ENSG00000173917 "Homeobox B2" P14652 17 48540894-48545109 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 156.5;Endometrial ciliated cells: 69.2;NK-cells: 58.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 13 "medulla oblongata: 14.9;pons: 10.9;spinal cord: 12.1;white matter: 10.7" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 54.5;EFO-21: 52.2;HEK 293: 59.1;HMC-1: 116.8;WM-115: 52.6" "Region enriched" "Detected in single" 34 "pons and medulla: 4.4" "Group enriched" "Detected in some" 4 "medulla oblongata: 4.9;spinal cord: 7.0" HPA047857 Supported Nucleoplasm NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 1: Thyroid gland - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA047857: AB_2680184" "unprognostic (8.58e-3)" "unprognostic (4.39e-2)" "unprognostic (4.13e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (3.16e-1)" "unprognostic (2.12e-2)" "unprognostic (7.72e-2)" "unprognostic (3.57e-1)" "unprognostic (1.75e-2)" "unprognostic (2.60e-1)" "unprognostic (3.24e-1)" "unprognostic (3.04e-3)" "unprognostic (4.12e-1)" "unprognostic (5.75e-2)" "unprognostic (5.29e-2)" "unprognostic (2.89e-1)" 26.7 29.0 0.2 6.6 0.2 3.6 21.7 0.4 0.3 20.8 0.3 44.5 3.5 17.4 42.7 24.0 33.6 5.2 11.7 0.2 0.2 47.5 5.0 15.6 7.2 14.9 0.9 3.4 3.7 19.6 0.4 2.4 10.9 13.7 2.4 0.0 0.8 12.0 9.9 8.9 17.3 5.3 12.1 16.4 16.5 3.4 0.3 4.2 6.7 7.8 2.0 11.1 18.7 10.7 0.3 1.9 54.5 0.1 12.1 14.0 0.2 5.1 0.0 0.1 0.0 0.7 0.4 0.0 52.2 15.3 0.0 0.0 8.2 0.0 0.1 0.2 59.1 21.4 2.7 0.0 21.3 0.0 116.8 8.9 0.0 23.3 9.2 0.5 8.6 0.2 42.3 0.1 31.9 0.1 0.1 0.1 0.0 1.3 0.2 0.0 26.9 0.1 38.9 4.9 0.0 0.0 4.0 0.0 34.3 3.8 28.9 0.0 0.3 0.0 3.5 0.6 0.1 0.0 0.1 0.1 20.8 0.0 52.6 3.9 0.3 0.0 3.0 0.4 1.0 0.2 4.6 3.4 1.5 0.5 6.8 2.9 0.0 1.8 0.3 4.8 6.1 1.0 0.2 0.2 0.4 0.3 0.2 0.2 14.9 0.9 10.9 12.1 0.3 10.7 27.9 3.2 1.1 0.0 4.9 7.0 7.3 0.5 53.5 0.0 18.5 18.7 2.5 0.0 2.0 53.3 0.0 15.9 26.9 1.0 156.5 1.4 0.5 69.2 9.9 21.4 2.4 21.9 0.0 0.2 30.2 19.4 0.0 42.4 21.0 0.0 31.1 0.3 7.6 0.0 0.0 1.6 24.4 10.4 21.2 1.7 0.0 11.4 12.4 2.8 7.5 0.0 58.7 0.0 0.1 0.1 1.7 0.0 3.7 8.8 0.1 26.1 0.9 0.0 0.0 9.6 31.6 7.4 6.6 36.6 5.7 24.9 28.6 0.1 0.9 28.0 IDUA "MPS1, MPSI" ENSG00000127415 Alpha-L-iduronidase P35475 4 986997-1004564 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Leydig cells: 19.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 29.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025901, HPA046979, HPA054254" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 170000 "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "CAB025901: , HPA046979: AB_2679888, HPA054254: AB_2682429" "unprognostic (3.62e-2)" "unprognostic (9.08e-2)" "prognostic unfavorable (3.13e-4)" "unprognostic (7.23e-2)" "unprognostic (1.45e-1)" "unprognostic (2.31e-2)" "unprognostic (1.83e-1)" "unprognostic (1.67e-1)" "unprognostic (1.43e-2)" "unprognostic (1.89e-3)" "unprognostic (2.64e-2)" "unprognostic (4.61e-3)" "prognostic unfavorable (7.87e-5)" "unprognostic (2.24e-1)" "unprognostic (1.55e-1)" "unprognostic (2.46e-2)" "prognostic favorable (8.04e-5)" 13.5 17.6 3.4 2.2 3.4 2.9 16.1 9.2 7.5 17.5 2.9 10.3 3.6 15.4 2.4 9.9 16.3 3.7 11.6 3.8 1.5 15.9 13.6 13.9 3.5 3.2 2.1 17.0 21.0 2.8 17.2 1.7 2.4 18.5 1.8 1.8 16.6 4.5 3.7 8.9 14.3 2.0 1.0 18.9 17.1 5.6 2.9 3.4 17.0 0.7 1.3 12.0 13.9 2.6 1.8 0.4 0.0 1.1 12.7 3.6 5.3 10.7 8.5 1.2 1.7 0.6 6.4 0.8 10.7 5.0 1.0 0.5 0.1 0.3 0.4 6.1 0.6 1.0 0.8 0.1 5.8 0.8 4.6 9.3 3.1 0.6 0.0 3.4 1.0 0.7 0.6 0.0 1.6 0.0 2.2 2.5 0.8 11.9 5.5 2.7 0.0 1.1 3.5 0.9 0.1 3.3 0.3 0.0 5.7 1.3 1.2 2.3 9.3 9.0 1.6 2.6 1.2 29.0 1.4 0.4 7.8 3.3 1.8 0.0 1.5 0.0 1.4 1.2 1.8 0.1 1.1 0.9 1.8 0.2 1.3 0.7 0.0 1.5 1.7 1.1 0.6 0.5 3.4 3.4 9.2 7.5 3.8 1.5 3.2 2.1 2.4 1.0 2.9 2.6 8.7 6.4 5.0 4.9 5.2 3.6 11.5 1.1 8.6 2.0 8.5 9.1 2.6 1.5 1.5 7.3 4.2 0.4 4.3 5.0 0.0 1.6 0.9 4.1 9.0 4.9 10.7 1.3 4.4 2.4 1.7 13.4 16.8 6.0 2.5 8.2 6.1 2.6 6.5 0.0 2.9 4.2 0.0 5.0 3.6 0.9 19.6 7.3 5.4 1.0 1.6 1.1 4.1 5.5 3.3 1.4 6.9 10.5 15.7 7.7 6.9 1.4 1.4 2.1 0.0 5.5 4.4 3.7 1.6 4.7 1.8 0.4 5.6 4.7 4.3 7.9 IER5L bA247A12.2 ENSG00000188483 "Immediate early response 5 like" Q5T953 9 129175552-129178261 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 177.5;Breast myoepithelial cells: 110.2;dendritic cells: 121.9;Endometrial stromal cells: 218.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 24.7;SiHa: 34.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA021327 Approved Nucleoplasm NA NA "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA021327: AB_2121674" "unprognostic (2.46e-1)" "unprognostic (3.73e-3)" "unprognostic (3.90e-3)" "unprognostic (8.49e-3)" "unprognostic (1.21e-1)" "unprognostic (5.65e-2)" "unprognostic (3.37e-3)" "prognostic unfavorable (1.48e-6)" "unprognostic (6.91e-3)" "unprognostic (1.45e-2)" "unprognostic (3.73e-1)" "unprognostic (3.99e-2)" "unprognostic (1.08e-3)" "unprognostic (7.23e-3)" "unprognostic (1.03e-1)" "unprognostic (5.50e-2)" "unprognostic (2.29e-1)" 21.4 10.6 3.7 1.2 4.7 0.4 10.7 3.5 7.3 39.4 2.1 9.4 0.8 13.9 2.1 9.4 16.6 1.9 21.6 3.3 4.1 27.2 14.6 13.1 0.7 6.2 4.1 18.9 4.8 0.6 10.7 1.4 4.8 12.3 0.4 0.5 7.5 3.3 3.5 7.5 5.7 1.0 3.7 6.3 9.1 4.7 4.6 0.3 12.4 0.9 0.3 16.2 19.5 4.8 8.6 24.7 6.9 13.3 5.0 7.9 20.9 12.6 1.1 1.9 1.9 1.3 13.8 0.2 4.9 2.9 5.5 18.6 0.3 1.5 0.3 1.2 1.8 0.0 5.7 2.4 3.8 0.3 0.2 8.6 1.9 1.4 0.2 10.8 0.9 0.2 0.7 4.4 0.3 22.1 0.3 1.1 0.6 2.2 12.9 1.2 0.5 3.8 7.6 1.2 3.1 4.1 34.8 11.1 15.7 2.8 3.4 2.2 5.1 11.7 7.0 7.9 18.3 2.4 1.7 0.3 14.9 2.5 5.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.7 4.7 3.5 7.3 3.3 4.1 6.2 4.1 4.8 3.7 4.6 4.8 177.5 16.0 1.7 12.7 25.5 6.8 9.2 11.1 27.9 6.1 52.7 110.2 1.6 25.8 10.7 47.8 0.0 3.9 121.9 34.7 9.8 14.5 0.7 87.1 218.9 42.6 10.7 0.8 13.1 27.1 11.8 41.4 19.9 102.7 0.0 2.2 30.0 11.7 31.0 3.3 4.3 20.6 26.4 17.0 17.2 1.6 10.8 64.7 14.2 15.0 7.4 13.9 0.0 2.0 1.4 20.0 12.5 7.2 11.2 9.8 8.4 17.3 13.4 2.8 26.3 41.8 99.0 0.1 3.6 37.6 4.5 8.1 55.1 3.9 15.4 7.7 IGF1 "IGF, IGF-I, IGF1A, IGFI" ENSG00000017427 "Insulin like growth factor 1" P05019 12 102395874-102481744 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" Deafness "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 86.7;cervix: 89.0" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 1279.3;Leydig cells: 1103.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.4" "Lineage enriched" "Detected in single" 24 "B-cells: 2.4" "Cell line enhanced" "Detected in some" "ASC diff: 37.9;HDLM-2: 49.6;K-562: 22.4;Karpas-707: 11.3;U-266/70: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048946 Approved "Secreted to blood" NA NA 103000000 330000000 "Cluster 24: B-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 36: Stromal cells - Cell proliferation" "HPA048946: AB_2680566" "unprognostic (1.25e-1)" "unprognostic (2.86e-3)" "unprognostic (1.46e-1)" "prognostic favorable (1.04e-4)" "unprognostic (1.52e-1)" "unprognostic (2.10e-1)" "unprognostic (1.59e-3)" "unprognostic (2.26e-1)" "unprognostic (9.98e-2)" "unprognostic (1.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.04e-2)" "unprognostic (2.34e-1)" "unprognostic (2.04e-2)" "unprognostic (1.55e-1)" "unprognostic (2.07e-1)" "unprognostic (1.11e-3)" 86.7 5.1 1.2 27.1 1.8 0.9 38.7 0.3 2.3 89.0 1.3 6.9 5.4 46.9 10.6 6.6 13.0 21.5 15.1 2.2 1.0 3.1 83.5 11.6 6.5 2.5 1.1 9.0 3.9 1.4 1.2 24.2 2.0 38.5 6.7 5.4 7.6 33.4 8.5 4.9 5.7 74.3 1.2 9.8 7.7 7.6 2.0 3.1 25.4 5.9 3.7 21.3 22.7 0.9 0.3 0.0 0.0 0.0 37.9 0.0 0.2 0.3 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 49.6 0.0 0.1 0.7 0.0 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 22.4 11.3 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.1 0.2 0.2 1.7 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.4 1.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 1.2 1.8 0.3 2.3 2.2 1.0 2.5 1.1 2.0 1.2 2.0 0.9 11.8 3.2 2.2 1.0 8.5 2.5 0.7 0.0 1.8 168.1 4.0 6.2 0.4 2.8 0.7 0.0 0.0 1.1 0.6 0.2 0.0 0.0 17.5 35.8 1279.3 38.9 0.0 5.3 1.2 0.6 1.5 259.7 2.6 34.5 0.0 0.3 6.4 243.0 122.0 0.0 123.9 0.0 16.2 25.8 12.5 58.0 1103.2 42.0 14.2 27.2 3.6 4.4 0.0 0.5 0.9 0.1 0.0 193.4 66.9 1.2 0.0 1.4 0.1 9.0 0.0 139.3 19.6 1.9 1.2 1.6 2.7 1.2 9.1 69.4 0.2 0.4 IL17D "FLJ30846, IL-17D, IL-27, IL27" ENSG00000172458 "Interleukin 17D" Q8TAD2 13 20702127-20723098 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 79.8;skeletal muscle: 131.1" "Cell type enhanced" "Detected in many" "Astrocytes: 64.0;Early spermatids: 19.3;Excitatory neurons: 17.5;Late spermatids: 35.0;Muller glia cells: 20.2;Oligodendrocyte precursor cells: 20.6" "Group enriched" "Detected in many" 9 "glioma: 10.8;melanoma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "TIME: 27.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 25000 "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.76e-2)" "unprognostic (2.05e-1)" "unprognostic (1.38e-2)" "unprognostic (2.23e-1)" "unprognostic (4.26e-2)" "unprognostic (3.86e-2)" "unprognostic (5.96e-2)" "unprognostic (1.37e-2)" "unprognostic (4.00e-2)" "unprognostic (3.28e-2)" "unprognostic (1.35e-3)" "unprognostic (1.43e-1)" "unprognostic (1.33e-3)" "unprognostic (1.68e-1)" "unprognostic (2.32e-1)" "unprognostic (7.93e-2)" "unprognostic (5.97e-2)" 8.4 5.7 71.9 1.6 79.7 0.4 6.4 68.7 58.7 15.2 21.6 5.6 9.4 6.5 1.1 8.9 5.0 5.1 11.6 66.0 70.9 2.6 0.8 6.2 1.2 79.1 62.2 9.3 5.9 0.4 8.9 1.6 61.8 5.5 0.5 10.6 4.3 1.6 131.1 5.4 5.7 1.2 79.6 0.9 4.4 3.9 68.2 0.2 7.6 24.5 0.3 5.4 9.9 79.8 16.5 2.2 3.5 7.6 8.1 4.6 18.3 4.5 1.1 0.4 0.8 7.6 8.7 11.0 0.8 0.4 5.3 8.5 1.5 0.1 0.2 4.0 12.2 0.8 0.7 9.1 1.0 12.2 2.4 6.3 0.1 0.6 0.0 6.9 5.0 15.3 4.5 0.0 3.0 15.9 13.6 10.0 10.7 19.2 2.6 17.8 8.6 1.3 0.2 14.1 20.7 6.7 2.6 3.8 18.3 6.1 9.6 10.4 27.1 1.7 3.0 1.4 5.7 2.0 1.7 2.9 4.0 5.7 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 71.9 79.7 68.7 58.7 66.0 70.9 79.1 62.2 61.8 79.6 68.2 79.8 0.7 0.0 0.0 64.0 0.2 2.4 0.3 0.0 1.2 1.2 0.4 0.4 1.0 0.0 0.0 0.0 0.0 1.1 0.3 0.7 0.0 0.1 19.3 0.2 1.6 0.6 0.0 0.4 17.5 0.2 7.4 7.6 0.0 0.7 0.0 0.9 1.4 0.0 0.4 0.0 12.2 0.1 0.0 0.3 1.9 35.0 11.5 0.2 8.8 2.8 0.0 20.2 0.0 20.6 12.5 0.2 0.1 1.2 0.0 0.5 0.2 0.2 0.0 4.9 0.0 9.4 2.0 8.6 0.6 0.0 2.0 1.1 0.3 0.1 0.3 0.2 INAFM1 PRR24 ENSG00000257704 "InaF motif containing 1" C9JVW0 19 47274885-47275723 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 100.3;Smooth muscle cells: 73.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 58.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 43.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA064015 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 36: Stromal cells - Cell proliferation" "HPA064015: AB_2685177" "unprognostic (3.88e-2)" "unprognostic (8.88e-3)" "prognostic unfavorable (3.20e-5)" "unprognostic (7.46e-2)" "unprognostic (1.48e-1)" "unprognostic (1.15e-2)" "unprognostic (3.60e-1)" "unprognostic (2.32e-1)" "unprognostic (3.57e-2)" "unprognostic (1.31e-1)" "unprognostic (2.22e-2)" "unprognostic (9.99e-2)" "prognostic unfavorable (3.04e-4)" "unprognostic (3.52e-2)" "unprognostic (2.02e-1)" "unprognostic (4.03e-1)" "unprognostic (4.36e-3)" 24.1 65.4 26.3 9.0 25.3 9.0 22.8 23.5 30.3 39.6 29.2 34.5 6.4 32.3 4.8 14.7 31.4 9.8 23.8 27.2 34.7 22.6 18.1 26.0 5.5 31.8 31.6 33.9 27.7 4.6 21.0 6.6 27.8 32.4 3.4 16.1 15.2 9.0 17.0 25.3 15.9 9.3 23.8 18.5 23.0 12.9 31.6 4.9 21.6 4.9 3.3 31.2 26.9 22.1 11.1 10.1 8.8 14.4 2.6 7.7 5.2 12.6 4.2 5.7 7.4 4.9 4.9 5.8 3.9 7.8 4.5 8.0 2.2 5.0 1.4 11.6 13.6 9.3 6.3 7.7 13.1 6.7 13.6 10.9 8.9 5.4 4.8 4.2 2.3 6.4 15.1 12.4 2.3 22.5 5.1 43.1 2.6 11.2 10.1 9.0 3.5 4.8 4.5 6.5 6.6 8.4 13.8 4.3 6.2 2.3 6.1 6.5 5.4 6.5 9.6 3.7 6.7 5.9 5.0 5.5 13.4 4.7 5.8 11.0 15.4 36.3 3.1 11.0 2.5 11.3 3.6 4.3 13.6 8.6 6.6 4.7 58.6 2.9 14.4 16.0 5.0 7.1 26.3 25.3 23.5 30.3 27.2 34.7 31.8 31.6 27.8 23.8 31.6 22.1 23.8 9.6 7.0 7.5 6.3 0.0 43.5 0.0 15.9 16.5 20.7 20.8 9.4 8.6 3.7 11.0 10.4 20.1 3.1 12.6 19.6 11.4 13.5 16.4 100.3 18.3 7.3 18.9 5.0 12.4 15.3 30.5 11.7 16.5 1.3 10.2 11.4 14.8 10.0 3.3 11.6 13.0 0.0 15.9 0.0 22.9 61.8 12.3 0.0 4.7 8.0 5.9 8.2 3.5 2.7 9.6 17.7 25.9 9.0 31.3 28.4 15.4 0.7 48.6 46.0 12.9 73.4 10.3 13.0 10.6 0.0 27.6 6.5 16.2 13.2 49.0 ISLR HsT17563 ENSG00000129009 "Immunoglobulin superfamily containing leucine rich repeat" O14498 15 74173710-74176872 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 193.5;Fibroblasts: 154.5;Leydig cells: 214.9;Peritubular cells: 159.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 62.7;ASC TERT1: 33.5;fHDF/TERT166: 148.1;HSkMC: 25.5;RPMI-8226: 47.0" "Region enriched" "Detected in all" 5 "olfactory bulb: 118.0" "Region enriched" "Detected in all" 5 "spinal cord: 124.7" "HPA040326, HPA050811" Approved Approved "Golgi apparatus,Plasma membrane" "Secreted - unknown location" NA NA 130000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Golgi apparatus" "HPA040326: AB_2676928, HPA050811: AB_2681243" "unprognostic (2.58e-1)" "unprognostic (1.36e-2)" "unprognostic (3.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.21e-1)" "unprognostic (6.76e-3)" "unprognostic (1.16e-2)" "unprognostic (6.81e-2)" "unprognostic (8.93e-3)" "prognostic unfavorable (4.89e-8)" "unprognostic (1.64e-2)" "unprognostic (3.42e-2)" "unprognostic (2.28e-1)" "unprognostic (9.86e-3)" 89.3 17.5 4.4 5.5 11.8 0.0 66.9 1.7 10.4 216.2 5.4 75.1 5.7 181.4 18.9 17.1 78.7 38.6 63.3 4.6 5.2 20.9 8.2 37.7 9.9 2.8 3.2 170.9 10.1 2.1 44.6 10.2 2.8 51.4 5.2 0.3 33.6 22.9 18.5 46.7 31.3 26.3 2.3 33.0 32.5 14.9 4.5 3.3 63.4 19.7 5.3 63.5 111.9 5.0 0.0 1.5 0.1 0.0 62.7 33.5 0.2 10.2 0.1 0.0 0.0 0.0 4.0 0.0 0.6 148.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 25.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 47.0 0.0 0.0 0.5 5.8 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.3 0.4 7.6 0.1 0.1 1.1 0.0 0.3 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 11.8 1.7 10.4 4.6 5.2 2.8 3.2 2.8 2.3 4.5 5.0 10.3 0.0 1.3 0.7 0.1 11.7 0.1 0.2 0.0 0.1 4.8 3.9 3.9 1.5 0.7 0.0 0.0 1.3 0.8 0.0 0.0 0.2 2.4 7.2 193.5 14.0 0.0 0.0 1.9 0.2 1.4 154.5 2.0 4.2 0.0 0.0 7.5 0.0 3.8 0.0 0.2 0.0 0.0 0.0 16.2 6.1 214.9 2.6 12.4 34.7 0.0 0.2 0.0 0.5 0.7 0.8 0.0 159.9 0.0 0.1 0.0 0.1 1.5 0.5 26.3 7.0 49.8 0.7 0.7 1.3 8.8 1.0 2.6 7.0 0.0 0.2 ITIH5 MGC10848 ENSG00000123243 "Inter-alpha-trypsin inhibitor heavy chain 5" 10 7559270-7666998 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 112.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 282.7;Fibroblasts: 111.3;Microglial cells: 160.2;Smooth muscle cells: 110.1;Syncytiotrophoblasts: 221.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "WM-115: 102.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038305 Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" Vesicles "HPA038305: AB_10670662" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "unprognostic (3.11e-3)" "unprognostic (6.80e-2)" "unprognostic (1.80e-1)" "unprognostic (5.84e-3)" "unprognostic (1.63e-1)" "unprognostic (2.55e-2)" "unprognostic (1.53e-1)" "unprognostic (2.90e-1)" "unprognostic (5.80e-3)" "unprognostic (6.11e-2)" "unprognostic (1.36e-1)" "unprognostic (6.79e-3)" "unprognostic (2.00e-2)" "unprognostic (4.50e-2)" "unprognostic (3.48e-2)" 112.7 3.7 17.9 19.4 18.6 0.2 53.3 19.7 23.2 17.4 28.6 62.7 13.9 24.3 6.3 21.4 10.5 27.7 16.8 14.7 18.0 16.4 1.6 22.4 12.5 18.9 18.1 21.2 15.0 6.3 5.4 86.9 19.7 24.0 16.8 3.5 9.5 46.6 17.8 12.0 21.6 28.8 15.7 3.4 24.0 6.2 22.5 3.8 24.5 22.5 13.4 51.4 15.3 15.2 0.0 0.0 0.0 0.1 0.0 0.0 7.0 18.0 0.0 0.0 0.0 0.0 0.1 0.0 3.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 5.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.5 14.8 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.2 0.1 0.0 0.0 0.0 102.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.9 18.6 19.7 23.2 14.7 18.0 18.9 18.1 19.7 15.7 22.5 15.2 74.9 3.2 2.7 1.3 0.2 11.3 3.0 0.1 6.8 2.7 1.6 17.3 8.7 8.6 3.7 0.0 2.1 282.7 0.8 0.1 0.0 25.7 2.0 18.7 1.5 58.8 0.0 0.0 0.5 0.4 70.2 111.3 0.0 34.1 2.5 0.5 1.8 0.1 20.7 0.0 0.7 0.0 8.2 1.2 19.6 2.2 5.3 3.6 14.2 160.2 1.1 21.9 0.0 1.5 1.0 0.3 0.0 15.4 0.9 1.8 0.2 2.1 0.7 3.2 78.9 32.3 110.1 1.7 7.7 0.7 8.8 221.9 3.0 0.3 0.0 1.6 JUNB ENSG00000171223 "JunB proto-oncogene, AP-1 transcription factor subunit" P17275 19 12791486-12793315 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 679.4" "Group enriched" "Detected in all" 5 "granulocytes: 679.4;monocytes: 182.7" "Cell line enhanced" "Detected in all" "HDLM-2: 629.0;U-266/70: 256.4;U-266/84: 411.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004464, HPA019149" Approved Supported Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB004464: AB_2130023, HPA019149: AB_1852053" "unprognostic (1.03e-2)" "unprognostic (1.10e-1)" "unprognostic (2.11e-1)" "unprognostic (1.04e-1)" "unprognostic (7.17e-2)" "unprognostic (1.77e-2)" "unprognostic (2.19e-1)" "unprognostic (2.13e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (3.65e-4)" "unprognostic (1.79e-1)" "unprognostic (9.78e-2)" "prognostic unfavorable (1.05e-4)" "unprognostic (7.20e-2)" "unprognostic (7.06e-2)" "unprognostic (3.77e-1)" "unprognostic (1.02e-1)" 722.8 259.5 22.9 110.3 28.0 455.2 248.5 90.1 65.2 283.3 30.4 287.0 52.8 130.1 2.2 449.1 874.8 92.6 383.5 28.3 68.8 184.2 279.0 399.2 65.0 83.5 29.8 649.5 150.0 20.8 351.9 39.4 33.6 195.0 22.0 32.0 131.6 56.1 144.6 605.9 145.0 58.1 51.5 153.3 309.8 30.0 31.3 78.8 198.7 73.3 12.9 333.0 330.6 34.8 52.9 10.4 2.8 6.4 11.3 27.4 10.2 22.8 19.2 11.0 10.0 6.8 30.4 18.2 77.4 8.4 33.5 98.5 2.5 34.3 1.2 629.0 9.9 18.0 42.2 9.0 15.1 24.3 80.5 34.9 97.6 10.0 7.5 22.0 5.3 12.9 48.1 32.6 3.6 158.8 16.8 147.5 1.7 36.1 40.0 22.4 7.7 38.8 7.5 65.5 23.7 36.0 98.4 59.5 30.5 1.7 10.5 27.0 17.6 32.2 18.7 64.3 28.9 256.4 411.4 17.1 37.7 62.7 8.9 29.1 132.2 132.2 33.4 182.7 33.4 30.6 36.8 42.0 87.1 25.4 25.5 28.5 679.4 18.6 177.2 7.9 38.7 124.1 22.9 28.0 90.1 65.2 28.3 68.8 83.5 29.8 33.6 51.5 31.3 34.8 3158.0 115.4 423.2 130.2 1751.7 1463.9 1778.3 2367.7 1985.1 81.0 1296.9 1693.1 374.0 474.7 707.4 154.5 39.6 129.7 1766.9 819.7 49.0 833.3 9.5 468.5 1091.4 1469.5 1502.1 244.8 8.7 546.7 224.7 2182.3 1060.1 627.8 510.5 310.0 852.4 84.6 1178.4 21.9 4.4 1029.3 740.6 674.1 2747.6 27.9 815.2 1583.3 894.6 20.6 379.3 634.6 115.4 4.5 2.4 1026.7 875.3 263.3 842.5 1036.7 701.0 84.2 337.3 168.8 1163.6 2566.6 2624.1 9.4 10.5 1164.3 1804.1 440.3 2362.6 417.0 687.7 472.6 JUND AP-1 ENSG00000130522 "JunD proto-oncogene, AP-1 transcription factor subunit" P17535 19 18279694-18281622 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 2129.8;dendritic cells: 1844.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005268, HPA063029" Supported Supported Nucleoplasm No No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 35: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB005268: AB_2130177, HPA063029: AB_2684925" "prognostic favorable (6.15e-5)" "unprognostic (4.18e-3)" "unprognostic (8.89e-2)" "unprognostic (2.52e-1)" "unprognostic (3.70e-1)" "unprognostic (6.39e-2)" "unprognostic (1.63e-2)" "unprognostic (6.35e-2)" "unprognostic (3.48e-2)" "unprognostic (2.00e-1)" "unprognostic (3.37e-3)" "unprognostic (4.09e-2)" "unprognostic (3.35e-2)" "unprognostic (1.22e-1)" "unprognostic (3.99e-1)" "unprognostic (5.37e-2)" "unprognostic (1.49e-1)" 296.3 189.3 190.3 38.9 201.6 429.1 257.3 172.1 208.5 159.7 153.1 185.2 62.9 186.6 37.5 118.3 291.4 30.0 210.6 187.5 192.5 148.8 211.8 227.3 28.8 261.3 213.2 424.2 178.4 40.4 256.4 45.1 180.9 159.1 33.0 25.7 112.7 33.8 81.0 287.7 161.3 57.5 182.5 100.5 201.4 97.4 180.4 58.2 154.8 37.1 15.9 129.5 147.7 263.8 84.2 35.3 33.3 37.9 25.9 28.8 150.5 35.0 40.8 19.2 25.4 38.3 72.9 42.1 39.4 34.8 31.1 46.1 8.2 8.3 9.5 84.6 75.9 62.7 30.3 84.9 58.6 29.5 81.4 27.8 33.7 20.0 25.9 44.5 15.3 18.8 86.5 119.8 5.2 113.6 89.9 92.5 69.7 22.7 50.6 32.7 20.9 94.0 27.8 13.1 184.2 75.1 41.7 45.4 122.0 37.5 38.6 43.9 54.7 11.8 54.8 74.4 20.9 171.3 73.8 36.3 41.5 44.7 27.9 10.5 6.5 6.8 4.9 8.2 3.8 8.4 6.4 4.5 4.9 8.7 4.5 5.0 19.7 4.8 8.3 11.3 5.7 2.4 190.3 201.6 172.1 208.5 187.5 192.5 261.3 213.2 180.9 182.5 180.4 263.8 2129.8 179.5 386.7 104.5 1176.8 317.1 400.4 76.0 188.4 129.8 1147.5 1419.1 158.8 291.7 84.4 257.5 79.2 78.5 1844.7 810.5 31.3 96.5 80.8 1026.0 1289.3 468.1 568.8 78.3 51.6 140.8 112.9 950.9 336.4 1561.4 257.7 514.1 338.4 436.1 100.1 139.7 41.0 569.6 67.1 332.7 506.0 59.2 123.3 847.7 249.1 65.6 91.7 625.2 27.8 44.7 132.0 154.4 464.2 88.8 734.5 253.6 538.1 65.4 90.4 174.3 131.5 1064.7 798.4 11.8 22.7 172.0 394.1 164.3 1158.2 448.7 297.4 232.7 KCNG1 "K13, KCNG, kH2, Kv6.1" ENSG00000026559 "Potassium voltage-gated channel modifier subfamily G member 1" Q9UIX4 20 51003656-51023107 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.8;endometrium 1: 87.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 53.7;Granulosa cells: 34.0;Syncytiotrophoblasts: 97.0" "Cancer enhanced" "Detected in many" "urothelial cancer: 8.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 20 "naive B-cell: 7.1" "Lineage enriched" "Detected in single" 71 "B-cells: 7.1" "Cell line enhanced" "Detected in many" "hTCEpi: 53.5;U-138 MG: 40.4;WM-115: 34.6" "Group enriched" "Detected in many" 5 "amygdala: 20.6;basal ganglia: 19.1;cerebral cortex: 14.9;hippocampal formation: 18.1;white matter: 9.1" "Group enriched" "Detected in all" 5 "amygdala: 12.6;basal ganglia: 11.1;cerebral cortex: 22.4;hippocampal formation: 16.8" "HPA039530, HPA040024" Approved Approved Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA039530: AB_10795144, HPA040024: AB_10796338" "unprognostic (1.19e-1)" "unprognostic (4.47e-2)" "unprognostic (8.70e-2)" "unprognostic (3.49e-2)" "unprognostic (4.07e-2)" "unprognostic (5.05e-4)" "unprognostic (2.53e-2)" "unprognostic (3.89e-3)" "unprognostic (3.64e-2)" "unprognostic (3.43e-2)" "unprognostic (8.74e-2)" "unprognostic (8.89e-2)" "unprognostic (1.83e-9)" "unprognostic (1.52e-1)" "unprognostic (7.42e-2)" "unprognostic (1.60e-1)" "unprognostic (1.02e-2)" 0.4 3.0 17.3 2.2 26.7 0.0 0.4 0.0 21.7 17.9 0.1 5.0 0.2 87.4 0.8 6.7 19.2 0.9 1.3 14.9 0.6 0.5 0.2 0.3 2.2 28.9 46.8 0.7 2.7 4.1 0.8 7.1 3.2 5.6 0.8 0.1 2.2 12.8 0.0 0.5 5.3 4.1 1.0 2.7 0.7 9.5 1.2 0.2 0.2 0.0 0.9 3.4 6.2 1.1 0.9 3.6 2.7 13.3 1.5 3.4 0.2 11.6 0.1 6.7 5.3 0.2 0.2 0.0 7.1 3.5 18.8 3.4 1.7 3.5 6.9 0.4 4.7 0.0 13.6 0.0 23.2 0.0 0.4 6.8 53.5 25.7 26.1 1.3 1.8 0.1 0.2 0.0 0.6 13.4 0.0 0.4 13.7 0.0 25.0 0.0 0.0 0.0 0.0 4.1 3.9 15.0 25.5 29.3 19.9 4.3 2.1 1.9 0.7 40.4 23.9 0.3 3.4 0.1 0.0 0.0 11.8 1.0 34.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 17.3 26.7 0.0 21.7 14.9 0.6 28.9 46.8 3.2 1.0 1.2 1.1 0.2 3.2 1.1 0.3 10.5 1.1 11.0 0.6 13.6 0.3 1.1 2.3 1.1 7.2 0.9 0.0 0.0 53.7 0.0 7.5 0.0 2.6 18.2 9.3 2.0 1.2 0.0 0.0 2.0 0.0 2.7 1.5 0.5 15.9 0.0 34.0 0.4 0.3 3.3 1.7 2.2 0.6 0.0 0.0 0.3 20.3 1.5 0.3 0.0 1.0 0.0 0.2 1.0 0.0 0.6 0.2 3.4 4.1 0.0 18.1 12.8 0.1 0.9 0.2 0.0 1.1 7.1 12.7 0.7 5.4 0.3 97.0 0.4 0.3 0.4 9.9 KCNMB4 ENSG00000135643 "Potassium calcium-activated channel subfamily M regulatory beta subunit 4" Q86W47 12 70366290-70434292 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.2;choroid plexus: 18.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 95.7;Hepatic stellate cells: 37.1;Inhibitory neurons: 45.0;Oligodendrocytes: 86.9" "Cancer enhanced" "Detected in many" "glioma: 10.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 7.7;RH-30: 8.2;RT4: 9.3;SuSa: 7.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072287 Enhanced Approved Approved Cytosol NA NA "Cluster 70: Brain - Nervous system development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA072287: AB_2686507" "unprognostic (3.90e-1)" "unprognostic (1.72e-2)" "unprognostic (2.69e-2)" "unprognostic (2.62e-2)" "unprognostic (6.98e-2)" "unprognostic (1.13e-3)" "unprognostic (1.85e-1)" "unprognostic (2.48e-2)" "unprognostic (3.50e-1)" "unprognostic (2.95e-2)" "unprognostic (3.75e-1)" "unprognostic (2.47e-2)" "unprognostic (2.19e-2)" "unprognostic (1.96e-1)" "unprognostic (1.78e-1)" "unprognostic (4.62e-2)" "unprognostic (1.05e-2)" 2.3 14.9 35.3 1.1 39.5 0.2 2.0 29.7 43.5 3.1 18.9 8.6 1.0 1.8 1.1 1.0 1.7 1.4 4.7 36.4 29.7 3.7 0.5 6.1 1.3 38.5 32.2 2.6 0.5 0.2 1.9 2.5 32.1 3.2 1.2 1.9 1.7 2.1 2.4 2.6 3.0 1.2 28.9 1.2 2.1 2.1 38.4 1.3 2.1 1.5 1.0 2.5 2.6 54.2 0.0 0.3 4.9 2.7 0.3 0.2 0.5 0.6 0.9 0.2 0.7 0.2 1.8 2.4 0.3 0.0 1.0 0.0 5.3 0.8 0.2 1.1 3.1 1.3 1.1 2.9 0.0 0.1 0.1 1.4 0.1 0.0 0.0 0.5 0.2 3.5 0.0 0.0 0.9 0.7 1.8 0.4 7.7 0.1 5.6 2.6 8.2 0.2 0.2 9.3 2.4 2.9 0.7 0.9 0.0 7.3 2.7 0.1 0.1 0.3 1.3 0.1 0.3 1.7 0.0 2.5 0.4 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.3 0.4 0.6 0.0 0.0 0.0 0.0 0.1 0.1 35.3 39.5 29.7 43.5 36.4 29.7 38.5 32.2 32.1 28.9 38.4 54.2 8.5 0.0 0.6 2.6 1.1 3.2 0.2 0.4 0.6 23.1 2.8 1.9 4.3 0.0 0.2 23.9 0.0 0.2 2.1 0.1 0.0 0.1 0.9 4.7 1.1 8.7 0.0 3.2 95.7 0.0 0.4 9.6 0.0 3.4 0.0 7.2 37.1 0.7 1.2 0.0 45.0 0.4 0.0 10.8 2.6 2.2 6.5 2.9 1.8 20.6 0.7 1.5 0.0 13.6 86.9 0.0 0.0 18.0 0.2 0.8 0.0 9.7 0.0 3.0 0.0 12.8 5.1 2.2 7.8 0.2 5.5 0.3 1.4 14.0 0.5 0.0 KCNN3 "hSK3, KCa2.3, SKCA3" ENSG00000143603 "Potassium calcium-activated channel subfamily N member 3" Q9UGI6 1 154697455-154870281 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 33.1" "Group enriched" "Detected in many" 4 "Astrocytes: 168.8;Skeletal myocytes: 121.5" "Cancer enhanced" "Detected in many" "glioma: 5.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.7;memory B-cell: 2.6" "Group enriched" "Detected in many" 11 "B-cells: 2.6;granulocytes: 4.7;monocytes: 1.4" "Cell line enhanced" "Detected in some" "Daudi: 39.3;HMC-1: 26.1;Karpas-707: 65.5;RPMI-8226: 18.7;U-266/70: 62.3;U-698: 21.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA057127 Enhanced Approved Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 29: U-266 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA057127: AB_2683345" "unprognostic (2.09e-1)" "unprognostic (2.91e-2)" "unprognostic (3.41e-2)" "unprognostic (1.04e-1)" "unprognostic (7.22e-2)" "unprognostic (4.06e-2)" "unprognostic (2.19e-2)" "unprognostic (2.03e-1)" "unprognostic (3.43e-2)" "unprognostic (9.51e-2)" "unprognostic (4.07e-3)" "unprognostic (4.89e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (1.71e-2)" "unprognostic (1.54e-1)" "unprognostic (6.93e-2)" "unprognostic (1.80e-2)" 0.9 1.1 24.9 3.9 24.2 0.3 0.7 15.1 12.8 2.7 0.0 7.4 3.0 4.9 0.6 1.7 5.7 1.5 2.1 16.9 18.5 2.1 0.2 1.5 3.5 14.4 33.1 0.8 0.3 1.1 1.2 0.0 16.5 1.6 2.4 0.3 1.3 1.2 6.1 0.3 2.2 6.0 12.9 3.5 2.4 0.5 25.7 1.0 1.9 5.3 5.5 3.1 1.6 11.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 39.3 3.1 0.0 0.1 0.1 0.9 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 26.1 0.5 0.0 0.3 0.0 0.1 0.8 0.1 0.0 65.5 0.6 0.1 0.2 0.0 0.8 0.0 2.5 0.0 16.2 18.7 0.0 0.0 0.8 0.4 0.0 0.1 0.0 0.2 0.0 0.0 1.2 1.1 0.0 0.0 0.0 62.3 8.8 21.4 0.6 0.0 6.2 4.7 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.1 24.9 24.2 15.1 12.8 16.9 18.5 14.4 33.1 16.5 12.9 25.7 11.0 8.7 12.8 2.7 168.8 3.9 1.3 0.6 0.7 0.6 0.5 0.1 0.0 3.4 0.0 2.1 0.0 2.1 0.1 0.0 0.0 3.9 0.2 3.4 26.6 0.6 25.9 4.2 0.0 18.2 0.2 0.0 16.3 0.0 5.8 0.0 2.0 13.9 0.3 0.4 0.0 13.6 0.0 4.1 0.0 3.0 7.7 0.3 0.9 0.0 11.2 0.0 2.2 0.0 12.1 5.0 0.0 2.2 0.0 30.9 0.5 0.0 0.3 18.3 0.4 0.0 121.5 1.3 0.7 0.2 0.8 1.7 0.0 0.5 22.5 0.0 0.7 KCNS3 Kv9.3 ENSG00000170745 "Potassium voltage-gated channel modifier subfamily S member 3" Q9BQ31 2 17877847-18361616 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "lung: 23.5;skeletal muscle: 86.0;tongue: 45.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 28.9;Enteroendocrine cells: 32.5;Theca cells: 30.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 69.2;RPMI-8226: 28.9;RT4: 48.2;U-266/84: 34.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014864 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Golgi apparatus, Plasma membrane" "HPA014864: AB_1852155" "unprognostic (5.62e-2)" "unprognostic (4.27e-3)" "unprognostic (6.87e-2)" "unprognostic (1.68e-1)" "unprognostic (3.19e-1)" "unprognostic (1.64e-2)" "unprognostic (3.30e-1)" "unprognostic (9.47e-3)" "unprognostic (9.06e-2)" "unprognostic (8.45e-2)" "unprognostic (5.82e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (1.64e-2)" "unprognostic (2.34e-1)" "unprognostic (1.67e-1)" "unprognostic (4.71e-2)" 2.9 1.1 2.6 3.8 2.9 0.0 6.2 3.9 4.0 7.8 9.5 12.5 3.7 3.2 2.6 6.0 3.9 5.4 6.6 2.9 4.2 5.0 3.8 23.5 0.6 10.5 7.9 1.0 9.8 2.9 1.2 11.0 12.5 6.5 5.0 0.4 11.2 3.1 86.0 5.6 5.4 3.3 5.3 1.0 9.5 3.9 4.3 1.4 2.3 45.5 2.0 6.8 6.3 4.4 8.5 1.4 0.7 0.0 1.6 0.8 3.8 2.8 8.5 1.7 2.0 0.1 17.1 0.0 0.9 3.0 1.9 2.7 20.7 0.1 1.8 0.0 5.7 0.0 0.2 0.1 8.1 0.2 0.7 0.7 12.9 0.1 1.2 15.5 0.4 3.9 0.4 0.0 1.0 2.2 0.0 0.0 10.2 11.5 0.2 2.4 69.2 28.9 1.8 48.2 20.3 0.7 0.0 5.3 6.1 4.8 2.8 0.0 0.2 2.7 0.0 0.2 21.6 0.1 34.9 0.1 15.2 0.0 20.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.9 3.9 4.0 2.9 4.2 10.5 7.9 12.5 5.3 4.3 4.4 3.8 28.9 8.2 0.0 0.0 13.9 16.8 6.9 21.1 0.2 11.5 7.0 0.5 18.6 6.8 11.0 0.0 0.6 0.0 10.9 0.0 21.5 0.3 0.9 0.6 5.9 32.5 0.0 0.3 0.4 3.5 12.1 8.2 0.9 1.3 4.3 2.5 5.4 0.5 0.0 16.9 5.6 14.2 0.0 4.5 1.2 1.5 0.4 21.4 1.9 0.7 0.1 0.0 7.1 2.5 2.4 4.9 3.8 1.2 13.6 4.1 5.5 1.7 0.2 6.6 13.5 10.6 0.3 3.4 8.0 5.8 0.8 0.6 30.6 10.3 7.1 KCNT2 "KCa4.2, SLICK, SLO2.1" ENSG00000162687 "Potassium sodium-activated channel subfamily T member 2" Q6UVM3 1 196225779-196609225 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 3.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 220.2;Inhibitory neurons: 240.5;Oligodendrocyte precursor cells: 310.7" "Cancer enhanced" "Detected in some" "renal cancer: 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 3.2;hTERT-RPE1: 9.0;SCLC-21H: 7.5;SH-SY5Y: 5.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051218 Uncertain Approved Vesicles NA NA "Cluster 15: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA051218: AB_2681392" "unprognostic (5.06e-2)" "unprognostic (2.94e-2)" "unprognostic (8.01e-2)" "unprognostic (5.10e-6)" "unprognostic (1.22e-3)" "unprognostic (1.30e-2)" "unprognostic (1.07e-1)" "unprognostic (3.03e-2)" "unprognostic (5.90e-2)" "unprognostic (2.18e-1)" "unprognostic (9.56e-3)" "unprognostic (2.61e-1)" "prognostic unfavorable (1.67e-5)" "unprognostic (3.30e-4)" "unprognostic (2.95e-2)" "unprognostic (4.75e-1)" "unprognostic (1.72e-3)" 1.0 0.6 0.9 0.1 2.0 0.0 0.4 0.0 2.0 0.4 0.3 0.5 0.2 0.3 0.4 1.0 0.5 1.4 1.8 2.5 3.3 0.3 2.8 1.8 0.1 0.0 0.2 3.8 0.1 0.0 0.9 0.2 0.0 1.0 0.5 0.1 0.5 0.6 0.1 0.3 0.4 0.5 0.6 0.2 0.5 1.1 1.0 0.1 1.1 0.8 0.1 0.8 0.4 0.5 0.0 0.1 1.8 0.0 0.2 0.2 0.0 0.0 1.0 0.1 1.8 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.9 0.0 3.2 0.0 0.0 1.2 0.0 0.4 0.1 9.0 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 2.4 0.0 0.1 0.0 0.1 0.0 0.0 0.5 7.5 5.6 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 2.0 0.0 2.0 2.5 3.3 0.0 0.2 0.0 0.6 1.0 0.5 0.8 41.7 1.1 6.8 0.0 0.4 0.2 0.0 0.6 0.0 0.0 0.1 1.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.2 0.8 0.0 0.0 220.2 0.0 0.0 9.3 0.0 0.0 0.0 6.1 2.5 6.2 0.0 0.0 240.5 0.0 0.0 0.0 0.7 3.3 6.5 0.0 1.8 58.1 0.0 0.0 0.0 310.7 6.1 0.0 0.0 4.9 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.4 4.0 0.6 0.2 0.0 0.0 0.0 0.0 3.9 0.0 0.2 KIAA1755 RP5-1054A22.3 ENSG00000149633 KIAA1755 Q5JYT7 20 38210503-38260772 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 105.0" "Group enriched" "Detected in some" 4 "Astrocytes: 63.3;Microglial cells: 67.5;Oligodendrocytes: 135.6" "Cancer enhanced" "Detected in many" "melanoma: 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 75.6;ASC diff: 11.3;ASC TERT1: 16.9;WM-115: 19.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051064 Approved Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoli "Golgi apparatus, Vesicles" "HPA051064: AB_2681331" "unprognostic (3.98e-3)" "unprognostic (2.20e-2)" "unprognostic (3.79e-1)" "unprognostic (3.01e-3)" "unprognostic (1.77e-1)" "unprognostic (7.01e-2)" "unprognostic (2.22e-1)" "unprognostic (1.11e-1)" "unprognostic (4.50e-2)" "unprognostic (2.70e-1)" "unprognostic (3.88e-2)" "unprognostic (1.69e-1)" "unprognostic (2.42e-8)" "unprognostic (1.41e-2)" "unprognostic (2.78e-2)" "unprognostic (1.25e-2)" "unprognostic (5.53e-3)" 5.6 2.1 18.4 6.0 87.7 0.5 3.4 39.2 42.2 13.1 0.0 9.0 2.4 14.6 6.4 5.1 8.7 16.2 11.4 29.0 64.1 4.1 1.2 2.5 5.0 59.2 62.3 13.6 0.9 0.1 2.2 0.1 54.7 6.6 4.2 0.5 5.8 7.3 0.6 1.4 4.2 14.7 18.3 2.7 3.6 2.6 75.3 8.3 2.0 1.7 4.7 5.2 4.8 105.0 3.0 0.3 75.6 0.1 11.3 16.9 0.0 7.6 4.3 0.0 0.0 0.3 2.2 0.0 0.3 2.4 2.5 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 6.3 0.0 2.2 1.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 2.0 0.1 0.0 0.0 0.4 0.0 1.1 0.4 1.4 0.0 0.0 0.0 0.2 0.0 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.4 87.7 39.2 42.2 29.0 64.1 59.2 62.3 54.7 18.3 75.3 105.0 0.1 0.0 0.0 63.3 0.0 0.3 0.0 0.0 0.0 0.0 0.8 1.8 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 1.5 0.1 2.5 0.2 0.0 0.0 0.8 0.0 0.0 4.4 0.0 0.6 0.0 0.0 0.4 1.1 0.1 0.0 0.5 0.0 0.0 0.0 0.5 1.9 3.7 0.2 1.8 67.5 0.0 0.0 0.0 19.6 135.6 0.6 0.0 7.5 0.0 0.0 0.0 4.1 0.0 0.0 0.0 1.1 1.2 0.3 0.3 0.2 0.3 0.0 0.0 0.4 0.0 0.0 LAMB1 CLM ENSG00000091136 "Laminin subunit beta 1" P07942 7 107923799-108003213 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 185.6;Fibroblasts: 99.6;Peritubular cells: 141.8;Theca cells: 174.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 593.0;ASC TERT1: 815.3;HSkMC: 779.6;TIME: 547.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004056, HPA004132, CAB004256" Enhanced "Secreted to extracellular matrix" NA NA 250000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 52: Non-specific - Transcription" "CAB004256: AB_627867, HPA004056: AB_1079226, HPA004132: AB_1079225" "unprognostic (2.39e-1)" "unprognostic (6.45e-3)" "unprognostic (2.01e-1)" "unprognostic (6.75e-2)" "unprognostic (3.45e-3)" "unprognostic (8.26e-2)" "prognostic unfavorable (2.07e-4)" "unprognostic (3.77e-2)" "unprognostic (1.04e-2)" "unprognostic (2.04e-2)" "unprognostic (3.44e-1)" "unprognostic (5.01e-2)" "unprognostic (2.87e-2)" "unprognostic (4.50e-3)" "unprognostic (1.75e-1)" "unprognostic (4.45e-2)" "unprognostic (1.46e-1)" 141.4 21.8 1.2 26.5 1.6 0.1 74.1 0.9 1.7 46.4 23.0 87.0 29.3 78.9 3.3 25.2 44.1 53.4 53.9 2.4 0.7 81.4 14.7 104.3 9.4 0.0 0.8 29.4 48.2 12.1 11.8 154.3 0.2 18.1 40.4 0.7 24.6 29.7 20.4 39.3 67.5 73.2 0.1 42.4 49.5 11.4 1.4 19.7 43.5 40.6 5.2 53.5 31.0 0.4 94.5 148.6 77.3 3.6 593.0 815.3 291.9 103.5 182.5 68.6 72.1 306.7 166.6 0.0 127.7 200.3 90.8 41.9 24.8 143.6 49.9 0.1 24.8 4.8 52.6 87.9 364.3 0.0 2.8 779.6 49.0 175.9 193.4 409.2 450.0 2.8 17.0 0.0 126.5 29.9 0.1 0.5 42.9 54.9 103.6 0.4 51.9 0.3 238.5 96.0 24.3 142.1 75.1 100.9 68.5 180.2 37.6 1.1 547.1 179.9 44.3 60.2 133.1 0.0 0.2 0.4 89.9 0.0 301.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.6 0.9 1.7 2.4 0.7 0.0 0.8 0.2 0.1 1.4 0.4 81.8 0.0 5.6 2.9 2.2 8.9 5.2 16.7 10.8 12.1 2.0 9.5 16.3 15.7 7.6 27.6 4.2 85.5 3.5 10.5 3.9 18.0 2.0 22.6 185.6 57.8 19.2 0.0 51.6 11.2 27.1 99.6 2.6 34.6 2.5 2.9 20.7 3.5 10.1 8.4 23.7 8.0 8.2 2.8 3.8 4.7 71.1 2.4 8.8 11.2 2.0 2.1 5.2 6.0 3.2 21.6 17.0 141.8 0.4 3.6 9.5 11.6 2.9 8.6 52.6 10.2 54.4 5.5 5.1 4.7 6.7 32.6 3.2 174.7 19.2 2.1 LCAT ENSG00000213398 "Lecithin-cholesterol acyltransferase" P04180 16 67939750-67944131 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Acyltransferase, Hydrolase, Transferase" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 283.0" "Cell type enriched" "Detected in many" 8 "Hepatocytes: 219.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 76.5;Hep G2: 62.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 29.2" HPA044767 Approved Nucleoplasm "Secreted to blood" NA NA 6470000000 6400000000 "Cluster 52: Eosinophils - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 15: Hepatocytes - Hemostasis" Nucleoplasm "HPA044767: AB_2756312" "unprognostic (3.34e-2)" "unprognostic (3.56e-2)" "prognostic unfavorable (8.50e-4)" "unprognostic (5.43e-3)" "unprognostic (1.25e-2)" "unprognostic (2.16e-1)" "prognostic favorable (4.21e-8)" "unprognostic (6.42e-2)" "unprognostic (4.26e-1)" "unprognostic (4.12e-1)" "unprognostic (1.50e-2)" "unprognostic (7.21e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (9.93e-2)" "unprognostic (1.83e-1)" "unprognostic (2.85e-1)" "unprognostic (1.90e-3)" 29.5 20.8 29.3 8.3 29.8 4.2 27.2 56.7 37.5 41.4 37.8 30.6 5.0 28.7 9.1 13.4 26.1 11.5 42.0 28.5 32.3 33.2 283.0 36.1 7.5 41.9 32.7 28.5 17.7 8.0 17.5 17.8 31.6 40.0 4.8 2.8 16.9 18.6 13.2 32.0 17.8 12.3 31.9 23.3 16.5 11.3 33.4 9.4 43.2 8.9 4.4 27.5 27.3 32.0 5.7 9.0 13.0 14.8 11.1 15.6 76.5 21.9 9.3 14.5 10.2 29.5 6.8 3.1 4.0 31.9 5.3 19.4 3.1 30.0 8.9 1.5 7.9 3.9 22.8 62.9 15.2 0.7 10.3 27.1 27.9 30.0 10.4 19.5 10.8 8.7 8.7 1.2 10.5 9.1 3.7 9.5 8.6 1.1 5.0 4.0 14.1 3.3 4.1 9.6 0.5 6.7 33.1 1.6 3.9 26.5 18.6 6.0 20.6 18.5 28.8 20.7 8.1 17.7 5.2 8.3 8.9 2.5 16.5 0.9 0.4 1.9 0.3 0.0 0.4 0.4 0.2 0.3 0.1 0.6 0.4 0.1 1.0 0.4 0.1 0.3 0.0 0.0 29.3 29.8 56.7 37.5 28.5 32.3 41.9 32.7 31.6 31.9 33.4 32.0 16.5 9.6 4.8 27.4 1.1 9.4 4.1 4.6 6.8 0.4 1.9 5.5 7.9 5.7 3.3 3.7 2.1 7.7 1.3 0.1 0.0 1.7 0.2 2.1 6.0 8.0 1.2 14.3 0.1 1.0 3.4 7.3 1.1 1.6 1.3 5.4 10.8 219.5 2.4 0.0 0.1 0.0 4.1 6.6 3.8 1.3 8.7 2.4 7.2 6.5 3.0 7.7 1.0 4.5 1.4 2.1 0.0 8.6 1.9 4.3 0.0 0.4 4.4 0.6 13.1 7.6 10.4 0.9 1.4 0.9 2.6 12.2 1.6 4.1 0.1 1.7 LDLRAD2 ENSG00000187942 "Low density lipoprotein receptor class A domain containing 2" Q5SZI1 1 21812265-21825225 "Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 2.2;Granulosa cells: 4.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 1.2;THP-1: 1.0;TIME: 2.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "basal ganglia: 4.0;midbrain: 5.9" HPA030478 Approved "Secreted - unknown location" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "HPA030478: AB_10601541" "unprognostic (4.16e-2)" "unprognostic (1.22e-1)" "unprognostic (4.13e-2)" "unprognostic (4.21e-2)" "unprognostic (1.78e-1)" "unprognostic (6.22e-3)" "unprognostic (1.35e-2)" "unprognostic (4.85e-2)" "unprognostic (7.52e-2)" "unprognostic (3.80e-2)" "unprognostic (5.34e-2)" "unprognostic (5.38e-2)" "unprognostic (1.04e-3)" "unprognostic (7.39e-3)" "unprognostic (3.14e-1)" "unprognostic (1.26e-1)" "unprognostic (6.94e-2)" 3.7 2.8 0.4 0.8 0.3 1.0 3.0 0.2 0.1 2.7 0.4 4.3 1.6 3.5 0.0 1.7 2.7 0.5 6.8 0.7 1.1 2.2 0.7 1.6 0.7 2.4 3.3 1.1 2.0 0.0 1.5 0.1 1.7 3.7 0.1 0.0 7.2 0.0 1.2 1.3 2.4 0.1 1.7 2.7 3.7 1.4 1.4 0.0 2.2 0.0 0.3 3.9 2.4 0.3 0.2 0.2 0.1 0.2 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.5 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.9 0.1 0.1 1.2 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.0 1.0 2.2 0.2 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.4 0.3 0.2 0.1 0.7 1.1 2.4 3.3 1.7 1.7 1.4 0.3 2.2 0.0 0.6 0.0 0.6 0.5 0.1 0.4 0.6 0.0 0.1 0.1 0.7 0.0 0.2 1.8 0.0 0.2 0.3 0.0 0.0 0.2 1.7 0.3 1.2 1.6 0.0 1.3 0.2 0.0 0.6 1.3 0.0 0.9 0.0 4.9 0.7 0.2 0.3 0.0 0.1 0.0 0.0 0.3 0.2 0.4 0.0 0.3 0.0 1.0 0.5 0.0 0.0 0.0 0.2 0.3 0.1 0.0 1.3 0.5 0.0 0.0 0.8 0.0 0.0 1.2 0.7 0.6 1.2 0.1 0.4 0.3 0.4 0.4 0.0 0.0 LEFTY2 "EBAF, LEFTA, LEFTYA, TGFB4" ENSG00000143768 "Left-right determination factor 2" O00292 1 225936598-225941383 "Disease related genes, Predicted secreted proteins" "Cytokine, Developmental protein, Growth factor" "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 74.5;endometrium 1: 170.0" "Cell type enhanced" "Detected in some" "Early spermatids: 17.4;Endometrial stromal cells: 30.8;Granulosa cells: 43.6;Late spermatids: 34.6;Leydig cells: 18.0;Peritubular cells: 12.0" "Cancer enriched" "Detected in many" 8 "testis cancer: 41.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 10.6;NTERA-2: 44.4;RPMI-8226: 50.9;SuSa: 25.5" "CAB025801, HPA047883, HPA056210" Approved "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 36: Stromal cells - Cell proliferation" "CAB025801: , HPA047883: AB_2680200, HPA056210: AB_2683067" "unprognostic (3.78e-2)" "unprognostic (4.10e-3)" "unprognostic (5.79e-3)" "unprognostic (5.12e-2)" "unprognostic (1.80e-1)" "unprognostic (2.30e-1)" "unprognostic (1.52e-1)" "unprognostic (4.87e-2)" "unprognostic (9.75e-4)" "unprognostic (2.91e-1)" "unprognostic (3.84e-1)" "unprognostic (7.98e-2)" "unprognostic (9.14e-3)" "unprognostic (1.15e-1)" "unprognostic (4.69e-2)" "unprognostic (1.90e-4)" "unprognostic (1.64e-3)" 1.8 1.4 0.2 1.1 0.3 0.0 0.7 0.3 0.3 74.5 15.9 1.2 0.3 170.0 12.1 0.1 3.6 0.4 2.6 0.7 0.2 0.4 0.0 2.4 0.2 0.2 0.3 37.8 0.3 0.0 16.0 3.5 0.2 1.5 0.2 0.9 0.1 12.4 0.7 0.3 0.4 36.9 0.2 0.7 0.3 4.5 0.8 0.2 0.1 0.8 0.0 0.5 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 44.4 0.0 0.0 0.0 0.0 50.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 25.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.2 2.6 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.3 0.7 0.2 0.2 0.3 0.2 0.2 0.8 0.3 0.6 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 1.4 17.4 2.2 30.8 0.6 0.0 0.0 0.0 0.0 0.6 1.4 0.0 0.7 0.0 43.6 0.4 0.0 0.5 0.0 0.1 0.2 0.0 0.0 0.2 34.6 18.0 0.3 1.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 12.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 5.3 1.7 6.7 0.4 0.0 0.0 0.0 0.2 0.7 0.0 0.1 LIMA1 EPLIN ENSG00000050405 "LIM domain and actin binding 1" Q9UHB6 12 50175788-50283546 "Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 553.9;Basal prostatic cells: 646.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 523.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023871, HPA052645" Enhanced Enhanced "Plasma membrane,Actin filaments,Focal adhesion sites,Cytosol" NA NA 90000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "Focal adhesion sites, Cytosol" "HPA023871: AB_1852875, HPA052645: AB_2681898" "unprognostic (6.22e-2)" "unprognostic (9.39e-3)" "unprognostic (8.13e-2)" "unprognostic (1.42e-1)" "unprognostic (8.08e-2)" "prognostic unfavorable (1.76e-6)" "unprognostic (1.63e-1)" "unprognostic (2.29e-1)" "unprognostic (2.28e-2)" "unprognostic (2.65e-1)" "unprognostic (1.28e-3)" "unprognostic (6.27e-2)" "prognostic favorable (2.79e-4)" "unprognostic (7.12e-2)" "unprognostic (9.26e-3)" "unprognostic (1.46e-1)" "unprognostic (1.43e-1)" 122.2 47.1 11.9 39.9 13.6 4.2 89.4 40.3 16.4 63.3 12.3 125.6 112.1 56.8 33.2 37.1 47.9 69.3 31.9 11.7 13.1 48.7 20.7 62.5 32.6 15.4 13.8 38.6 31.1 31.0 24.0 50.6 17.3 45.7 130.5 32.2 47.2 42.2 21.9 47.3 121.8 48.6 13.3 40.8 96.8 16.2 13.1 38.1 33.3 28.3 33.8 96.7 53.2 16.3 154.3 4.5 47.2 69.7 211.9 211.0 177.7 377.2 264.4 296.9 235.8 57.7 220.2 6.8 34.1 523.4 99.7 170.8 42.8 348.7 258.1 98.1 45.1 64.2 16.2 20.5 135.3 23.2 87.5 142.2 100.8 104.6 297.8 89.0 106.2 28.3 45.6 30.3 96.9 26.5 29.0 7.1 24.3 81.0 20.5 28.7 115.2 2.4 68.7 180.3 35.2 75.4 51.5 102.7 166.6 50.0 49.0 14.1 166.7 126.5 98.0 118.4 62.1 16.5 2.0 28.0 137.6 25.3 55.6 0.2 0.2 1.5 6.6 1.1 2.6 0.2 8.2 8.1 4.9 0.6 3.3 6.0 0.1 5.9 2.7 1.2 15.3 3.0 11.9 13.6 40.3 16.4 11.7 13.1 15.4 13.8 17.3 13.3 13.1 16.3 123.2 44.8 91.2 13.4 4.8 553.9 646.1 175.4 283.4 14.6 62.2 73.0 7.3 61.5 179.1 119.5 160.6 128.1 15.5 413.7 15.6 145.6 67.1 75.7 183.9 91.8 122.8 17.5 12.9 307.6 376.9 170.9 126.9 132.6 24.7 15.9 117.8 19.8 34.4 6.7 30.1 138.0 187.2 11.7 59.3 11.7 75.5 19.3 90.7 41.2 9.9 22.7 28.8 78.9 48.4 219.0 244.5 77.5 6.9 221.6 214.8 22.3 67.8 95.4 65.7 54.9 118.0 30.8 10.4 100.0 291.5 64.0 33.3 62.4 244.3 385.1 LOX ENSG00000113083 "Lysyl oxidase" P28300 5 122063195-122078413 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 27.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 67.1;Club cells: 38.4;Early spermatids: 41.9;Endometrial stromal cells: 34.0;Extravillous trophoblasts: 44.2;Fibroblasts: 79.1;Peritubular cells: 39.1;Smooth muscle cells: 32.7" "Cancer enhanced" "Detected in all" "renal cancer: 39.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 777.3;fHDF/TERT166: 1790.7;HSkMC: 356.3;U-138 MG: 475.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA043930 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 550000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA043930: AB_2678736" "unprognostic (5.10e-2)" "unprognostic (1.03e-2)" "unprognostic (6.99e-3)" "unprognostic (3.64e-2)" "unprognostic (9.86e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (7.38e-4)" "unprognostic (2.42e-3)" "unprognostic (3.06e-3)" "unprognostic (8.92e-2)" "unprognostic (3.21e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (3.93e-8)" "unprognostic (1.11e-3)" "unprognostic (9.92e-2)" "unprognostic (4.31e-2)" "prognostic unfavorable (3.32e-4)" 27.9 2.4 0.4 6.8 0.4 0.2 17.6 0.5 0.9 10.8 0.8 4.2 3.8 6.2 1.7 5.6 8.9 18.8 23.9 0.3 0.4 4.5 2.1 13.6 3.3 1.3 1.4 5.4 3.3 0.9 1.2 8.1 0.8 4.1 4.5 1.1 3.2 2.6 1.9 12.4 3.7 10.0 1.2 2.6 4.4 1.4 0.5 0.9 6.9 2.1 1.4 14.1 4.8 1.0 0.8 0.2 2.0 0.9 168.7 185.2 0.1 777.3 205.3 73.2 246.4 0.5 0.3 0.1 16.5 1790.7 3.7 0.2 4.5 3.5 196.4 0.1 2.0 0.0 16.3 9.3 203.4 0.4 0.1 356.3 4.4 137.6 7.4 329.3 95.3 0.1 0.0 0.1 83.6 0.0 0.1 0.3 6.4 0.1 1.9 0.1 7.4 0.9 4.9 0.5 0.5 4.2 72.1 0.1 12.9 29.8 0.6 0.6 6.8 475.5 23.2 272.8 9.3 0.0 0.1 0.2 207.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.5 0.9 0.3 0.4 1.3 1.4 0.8 1.2 0.5 1.0 20.0 9.6 1.1 0.0 0.2 7.8 1.9 67.1 0.0 0.6 1.3 1.1 2.1 0.0 38.4 0.0 0.0 0.8 0.1 0.0 0.0 7.2 41.9 8.4 34.0 9.4 0.0 0.0 0.3 0.6 44.2 79.1 0.0 6.6 0.0 0.1 10.8 0.5 2.2 1.7 2.0 0.0 2.0 0.8 21.6 5.0 14.0 1.3 5.4 1.9 0.6 0.0 0.0 0.0 0.0 1.3 0.0 39.1 0.3 2.8 0.0 0.1 8.3 1.7 19.7 1.1 32.7 0.8 0.6 1.8 10.7 4.8 1.1 0.4 0.1 0.9 LOXL3 ENSG00000115318 "Lysyl oxidase like 3" P58215 2 74532258-74555690 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Inflammatory response" Oxidoreductase "Deafness, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 14.0;Hofbauer cells: 17.9;Kupffer cells: 12.5;Macrophages: 12.3;Microglial cells: 30.0;Muller glia cells: 10.6;Oligodendrocyte precursor cells: 11.6;Sertoli cells: 19.7" "Cancer enhanced" "Detected in many" "melanoma: 15.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 11.7;non-classical monocyte: 9.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 143.4;HDLM-2: 110.7;U-138 MG: 245.9;WM-115: 549.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035281 Approved "Secreted to extracellular matrix" NA NA 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 17: WM-115 - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA035281: AB_10601766" "unprognostic (7.54e-2)" "unprognostic (2.53e-2)" "unprognostic (5.34e-3)" "unprognostic (4.55e-3)" "unprognostic (6.85e-2)" "unprognostic (1.96e-1)" "unprognostic (1.68e-3)" "unprognostic (6.84e-2)" "unprognostic (1.41e-1)" "unprognostic (1.78e-1)" "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.97e-8)" "unprognostic (1.22e-2)" "unprognostic (7.33e-3)" "unprognostic (7.09e-2)" "unprognostic (3.38e-2)" 6.8 5.3 4.5 7.8 4.7 14.3 3.0 4.5 5.3 5.1 3.8 7.3 4.0 7.4 1.7 3.2 4.9 6.5 8.2 4.5 5.6 2.0 1.5 4.6 4.1 7.0 5.0 2.9 1.1 1.7 2.7 15.9 6.3 3.3 3.7 4.9 1.6 4.0 1.3 2.0 3.9 8.1 5.6 8.9 2.7 2.6 7.0 1.4 2.2 1.5 2.3 5.2 4.0 7.3 1.6 0.3 21.8 3.7 17.1 20.6 4.5 71.0 143.4 33.8 31.8 25.6 1.3 0.1 0.9 73.1 1.6 1.1 2.8 1.8 19.8 110.7 1.0 17.6 1.8 0.2 5.7 0.6 16.7 22.6 0.2 90.6 3.8 12.0 0.7 0.8 0.8 2.8 6.4 4.1 0.2 6.5 12.0 0.8 0.7 2.0 3.1 0.3 0.3 1.2 11.2 12.8 0.6 1.1 14.7 3.2 2.3 1.3 0.3 245.9 8.2 1.4 0.9 1.4 0.5 0.1 92.5 6.8 549.6 0.1 6.0 0.3 0.0 11.7 0.0 0.1 0.1 0.0 3.5 0.1 0.0 0.0 2.5 0.0 9.3 0.4 0.0 2.6 4.5 4.7 4.5 5.3 4.5 5.6 7.0 5.0 6.3 5.6 7.0 7.3 0.9 0.0 0.5 14.0 0.3 0.9 0.2 0.6 0.6 0.9 0.4 0.8 0.3 1.5 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.8 0.0 0.2 4.8 1.2 0.0 0.4 0.4 0.0 1.5 7.1 0.0 0.5 1.3 0.7 0.4 0.1 17.9 1.7 4.2 0.1 0.0 12.5 2.5 0.7 5.0 12.3 0.0 30.0 4.8 10.6 1.0 11.6 0.6 0.3 0.0 4.5 0.1 0.3 0.0 0.1 0.0 0.9 19.7 1.6 5.3 0.6 0.8 0.1 0.1 0.8 0.4 0.2 0.0 0.2 LPAR1 "edg-2, EDG2, Gpcr26, GPR26, LPA1, Mrec1.3, rec.1.3, vzg-1" ENSG00000198121 "Lysophosphatidic acid receptor 1" Q92633 9 110873263-111038458 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 358.4;choroid plexus: 122.2" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 626.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 9.1;eosinophil: 19.0" "Group enriched" "Detected in many" 6 "granulocytes: 19.0;monocytes: 9.1" "Cell line enhanced" "Detected in many" "ASC diff: 582.0;ASC TERT1: 337.0;BJ hTERT+: 426.7;HSkMC: 246.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050667 Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear speckles" "Plasma membrane" "HPA050667: " "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (4.79e-2)" "unprognostic (6.08e-3)" "unprognostic (1.03e-1)" "unprognostic (1.16e-1)" "unprognostic (2.17e-2)" "unprognostic (2.10e-1)" "unprognostic (1.40e-2)" "unprognostic (4.13e-2)" "unprognostic (1.02e-1)" "unprognostic (4.29e-3)" "unprognostic (2.12e-2)" "unprognostic (5.42e-3)" "unprognostic (2.78e-2)" "unprognostic (9.97e-3)" "unprognostic (1.65e-1)" 30.5 13.3 251.0 18.8 315.0 0.2 25.9 208.8 318.6 57.7 122.2 24.5 13.9 17.0 17.1 15.2 15.8 14.1 24.1 199.5 201.3 9.6 2.6 16.3 17.6 299.6 277.5 12.1 6.6 2.2 5.0 38.8 249.2 21.0 18.3 0.8 16.7 23.6 6.6 20.1 18.3 20.5 224.0 14.8 11.8 6.9 266.2 6.8 16.5 17.5 17.2 27.6 31.7 358.4 11.7 22.2 30.4 0.1 582.0 337.0 0.0 151.6 426.7 104.1 46.8 3.0 1.8 0.0 0.1 157.7 18.6 45.5 0.4 118.5 85.0 0.0 4.1 0.0 1.1 0.0 157.1 0.1 0.2 246.6 6.8 51.4 96.9 62.3 1.8 0.2 0.0 0.2 80.8 0.1 0.0 0.1 5.9 0.0 121.6 0.1 22.4 0.0 23.5 20.6 0.9 7.2 3.1 0.0 0.0 6.2 10.4 0.5 0.1 48.9 1.3 35.3 0.1 1.5 0.0 0.0 7.4 0.0 54.9 1.5 9.1 19.0 0.0 3.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 1.9 2.1 1.3 0.2 0.0 2.1 251.0 315.0 208.8 318.6 199.5 201.3 299.6 277.5 249.2 224.0 266.2 358.4 1.9 0.0 1.1 6.2 0.2 13.0 15.5 8.5 4.0 0.0 3.4 6.0 1.4 1.5 9.1 0.0 0.0 0.5 0.3 6.6 1.9 1.8 1.4 3.6 40.4 1.9 0.0 0.0 1.0 2.9 0.4 61.4 6.1 8.7 0.0 0.0 2.5 0.0 3.3 0.0 15.6 3.7 4.1 4.1 15.1 2.7 38.8 3.6 14.2 141.5 12.0 1.0 1.0 1.0 626.8 2.0 2.9 70.7 0.7 12.7 4.5 0.2 3.0 0.2 0.0 13.3 6.3 0.3 2.4 15.2 9.2 0.8 1.2 0.2 4.2 6.7 LRFN5 "C14orf146, FIGLER8, SALM5" ENSG00000165379 "Leucine rich repeat and fibronectin type III domain containing 5" Q96NI6 14 41606876-41904549 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.5;cervix: 10.1;parathyroid gland: 11.1" "Group enriched" "Detected in some" 19 "Excitatory neurons: 873.9;Inhibitory neurons: 581.5;Oligodendrocyte precursor cells: 296.1" "Cancer enhanced" "Detected in some" "testis cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 16.4;HSkMC: 3.1;RPTEC TERT1: 5.2;SCLC-21H: 8.8;U-138 MG: 10.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001177 Uncertain "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA001177: AB_1079274" "unprognostic (5.23e-3)" "unprognostic (1.37e-1)" "unprognostic (5.10e-1)" "unprognostic (6.24e-2)" "unprognostic (2.39e-1)" "unprognostic (3.54e-1)" "unprognostic (1.31e-1)" "unprognostic (6.38e-3)" "unprognostic (2.61e-2)" "unprognostic (5.78e-2)" "unprognostic (2.70e-2)" "unprognostic (9.27e-2)" "unprognostic (6.02e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (6.07e-3)" "unprognostic (2.92e-3)" 1.4 2.2 5.3 1.0 7.5 0.0 1.4 0.0 16.5 10.1 0.0 2.0 0.2 2.5 0.6 0.5 3.3 1.0 0.6 7.9 5.9 0.2 0.3 0.7 0.0 0.8 1.4 1.6 0.3 11.1 0.8 1.1 4.9 2.4 1.0 2.6 0.3 6.4 0.2 0.6 0.4 1.5 0.8 0.6 0.7 0.9 2.0 0.3 0.5 0.5 0.2 6.1 5.2 4.3 0.0 0.0 1.7 16.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 8.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 10.7 0.1 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 7.5 0.0 16.5 7.9 5.9 0.8 1.4 4.9 0.8 2.0 4.3 0.5 0.0 0.0 29.7 0.0 0.3 0.0 0.0 0.0 8.2 0.1 0.6 1.0 2.8 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 3.2 0.3 7.8 0.9 0.0 0.0 873.9 0.0 0.1 7.9 0.0 0.6 0.0 0.2 0.0 0.5 0.1 0.0 581.5 0.0 0.0 0.0 0.8 1.7 8.4 0.1 1.8 24.4 0.0 0.4 0.0 296.1 11.8 0.1 0.0 4.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 1.4 1.5 0.0 2.1 0.0 0.3 0.1 0.2 2.1 0.0 0.1 LRRC4C "KIAA1580, NGL-1" ENSG00000148948 "Leucine rich repeat containing 4C" Q9HCJ2 11 40114203-41459773 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.4;retina: 17.1" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 5497.5" "Cancer enhanced" "Detected in some" "glioma: 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AF22: 19.1;U-2 OS: 20.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054800, HPA075816" Supported Approved Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "HPA054800: AB_2682603, HPA075816: " "unprognostic (4.86e-3)" "unprognostic (3.43e-2)" "unprognostic (7.62e-3)" "unprognostic (4.87e-3)" "unprognostic (6.48e-2)" "unprognostic (1.42e-1)" "unprognostic (2.84e-1)" "unprognostic (4.64e-2)" "unprognostic (1.93e-1)" "unprognostic (2.22e-1)" "unprognostic (2.44e-1)" "unprognostic (1.49e-1)" "unprognostic (4.90e-13)" "unprognostic (5.05e-4)" "unprognostic (5.21e-1)" "unprognostic (1.12e-1)" "unprognostic (6.45e-3)" 0.7 3.4 11.4 0.8 14.1 0.0 1.4 0.5 15.4 3.0 0.0 2.5 0.4 1.2 0.3 0.4 0.5 0.8 2.1 14.4 9.6 0.3 1.1 0.8 0.7 7.8 10.7 0.6 0.3 1.7 4.0 0.0 5.7 0.6 0.7 17.1 0.6 1.6 0.3 0.2 0.8 1.3 4.6 0.6 0.5 0.2 8.1 0.6 2.3 0.7 0.7 0.7 2.0 9.2 0.0 0.0 19.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 20.9 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 14.1 0.5 15.4 14.4 9.6 7.8 10.7 5.7 4.6 8.1 9.2 0.2 0.0 1.3 498.2 0.2 0.1 0.0 1.4 0.0 35.5 4.2 3.0 1.2 0.0 1.4 0.0 6.2 0.0 0.0 0.0 1.9 0.0 0.9 0.3 10.5 1.4 0.0 0.0 1171.8 0.0 0.0 5.6 0.0 0.9 0.0 0.1 0.0 0.0 0.1 8.4 1274.6 0.0 0.0 0.0 1.9 0.2 2.1 0.4 1.8 49.6 0.0 93.6 0.0 5497.5 221.3 0.3 0.0 1.5 0.1 0.1 0.0 0.7 0.0 99.7 0.0 2.0 0.7 0.3 0.5 0.0 0.0 0.0 0.0 2.3 0.0 0.0 LRRN4CL ENSG00000177363 "LRRN4 C-terminal like" Q8ND94 11 62686406-62689530 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 62.1;Leydig cells: 27.1;Melanocytes: 33.8;Peritubular cells: 17.3;Skeletal myocytes: 33.0" "Cancer enriched" "Detected in many" 5 "melanoma: 26.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 7.7;ASC TERT1: 25.3;HHSteC: 19.8;HSkMC: 10.6;LHCN-M2: 13.4" "Low region specificity" "Detected in many" HPA050317 Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "HPA050317: AB_2681084" "unprognostic (1.28e-1)" "unprognostic (2.74e-2)" "unprognostic (2.84e-1)" "unprognostic (9.95e-3)" "unprognostic (2.61e-2)" "unprognostic (4.03e-3)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" "unprognostic (3.04e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (1.06e-1)" "unprognostic (1.35e-7)" "unprognostic (2.73e-2)" "unprognostic (6.12e-2)" "unprognostic (4.53e-3)" "unprognostic (1.86e-2)" 23.3 6.6 0.4 2.5 0.4 0.5 16.0 1.5 1.3 22.4 2.6 15.1 1.8 29.7 3.7 4.5 18.2 3.6 7.2 0.6 0.6 1.0 0.1 3.5 0.5 0.5 0.3 21.0 1.1 0.3 1.7 0.7 0.4 6.1 2.1 0.4 5.5 5.8 4.8 10.6 7.2 9.1 0.2 0.2 8.2 1.5 0.5 0.4 4.2 5.6 0.3 9.7 16.1 0.7 0.0 0.1 0.2 0.3 7.7 25.3 0.3 2.8 4.0 0.3 1.4 0.2 0.1 0.2 0.3 4.6 0.1 0.3 0.1 0.0 0.4 0.2 0.2 0.5 0.2 0.2 19.8 0.2 0.2 10.6 0.1 0.6 0.0 0.2 0.1 0.4 0.3 0.1 13.4 0.1 0.3 0.6 0.6 0.1 0.1 0.1 1.7 0.3 0.0 0.2 0.8 0.3 0.4 0.3 0.8 0.1 0.2 0.3 0.3 2.4 0.2 2.7 0.1 0.2 0.2 0.3 1.5 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.0 0.1 0.0 0.0 0.4 0.4 1.5 1.3 0.6 0.6 0.5 0.3 0.4 0.2 0.5 0.7 4.0 0.0 1.8 0.0 0.1 6.6 2.1 0.0 0.0 2.1 0.5 0.8 1.5 0.0 0.6 0.0 2.1 0.1 0.2 0.0 0.0 0.0 1.0 0.5 11.0 3.7 1.2 0.0 0.1 0.0 0.2 62.1 0.5 0.4 1.3 0.2 1.4 0.1 0.4 1.7 0.3 0.3 0.0 0.6 8.3 0.5 27.1 1.1 33.8 1.9 0.1 0.2 1.0 0.0 0.1 0.0 0.1 17.3 0.4 1.4 0.1 0.3 0.0 1.0 0.0 33.0 2.8 0.4 0.3 0.5 7.0 0.1 1.1 1.2 0.1 1.3 LSP1 WP34 ENSG00000130592 "Lymphocyte specific protein 1" P33241 11 1850904-1892267 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 224.7;lymphoid tissue: 245.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 492.2;Langerhans cells: 553.6;monocytes: 1505.6;NK-cells: 352.2;Plasma cells: 338.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 278.5;HDLM-2: 978.9;Karpas-707: 215.4;RPMI-8226: 500.2;U-937: 173.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017781, HPA019693" Enhanced NA NA 1600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "CAB017781: , HPA019693: AB_1853387" "unprognostic (7.53e-3)" "prognostic favorable (3.56e-4)" "unprognostic (4.35e-2)" "prognostic favorable (2.54e-4)" "prognostic unfavorable (5.35e-4)" "unprognostic (1.43e-3)" "unprognostic (3.82e-2)" "unprognostic (3.22e-1)" "unprognostic (1.13e-1)" "unprognostic (1.14e-1)" "unprognostic (6.10e-2)" "unprognostic (1.72e-1)" "unprognostic (1.03e-3)" "unprognostic (3.29e-1)" "unprognostic (6.33e-2)" "unprognostic (1.40e-1)" "unprognostic (6.20e-2)" 75.6 224.7 2.1 148.8 2.6 167.3 51.2 2.4 6.4 63.8 5.3 39.2 33.6 36.8 3.8 42.5 41.7 32.6 48.2 3.8 3.4 6.4 12.1 49.8 154.8 6.0 2.6 5.3 10.7 3.8 7.4 21.8 4.5 13.4 22.3 1.0 52.8 8.1 28.4 98.0 76.6 12.5 4.3 245.0 52.1 8.1 6.0 65.5 24.7 29.4 85.0 83.7 51.4 11.6 0.3 1.2 0.0 0.0 41.0 125.2 0.4 0.0 0.0 0.0 0.0 0.1 0.2 278.5 1.5 0.2 0.3 0.4 0.0 0.0 0.0 978.9 0.0 0.5 0.2 0.4 7.9 1.0 0.9 32.0 0.5 0.1 1.3 0.4 0.1 2.2 0.9 215.4 24.7 0.1 19.6 28.2 0.5 0.0 0.0 1.1 13.6 500.2 0.0 0.0 0.4 3.3 0.2 0.0 0.3 0.0 0.3 0.9 0.5 0.7 4.6 0.3 0.8 1.0 0.7 38.4 0.4 173.0 0.3 365.1 803.6 785.5 384.3 863.3 222.6 452.1 249.1 346.8 896.6 298.8 161.3 260.8 1574.3 279.6 888.2 669.7 491.4 1293.0 2.1 2.6 2.4 6.4 3.8 3.4 6.0 2.6 4.5 4.3 6.0 11.6 18.3 16.0 7.9 0.0 312.8 118.3 14.0 43.0 76.8 0.8 3.9 4.3 2.7 8.6 37.6 3.7 0.0 3.6 295.4 0.4 1.9 1.3 3.4 1.2 13.3 11.4 1.2 40.6 0.2 8.9 4.4 160.4 15.3 1.4 12.6 0.9 11.0 2.3 492.2 1.7 0.2 0.8 16.2 118.4 553.6 7.8 89.8 310.9 65.8 0.0 1505.6 0.2 352.2 0.5 0.1 1.4 1.4 30.1 338.4 1.1 1.2 12.9 36.6 1.0 0.0 182.1 15.9 0.4 1.3 16.7 114.7 6.4 310.1 92.7 3.2 67.3 MAPK10 "JNK3, p493F12, p54bSAPK, PRKM10" ENSG00000109339 "Mitogen-activated protein kinase 10" P53779 4 85990007-86594625 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 91.3" "Cell type enhanced" "Detected in many" "Astrocytes: 902.0;Excitatory neurons: 1018.9;Inhibitory neurons: 727.8;Late spermatids: 400.5;Oligodendrocyte precursor cells: 596.6;Oligodendrocytes: 302.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 6 "AF22: 155.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022625 Approved NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB022625: " "unprognostic (2.46e-2)" "unprognostic (4.36e-2)" "unprognostic (1.13e-1)" "unprognostic (4.05e-2)" "unprognostic (5.17e-2)" "unprognostic (2.03e-1)" "unprognostic (4.59e-2)" "unprognostic (4.82e-2)" "unprognostic (3.81e-2)" "unprognostic (4.45e-2)" "unprognostic (1.18e-3)" "unprognostic (3.02e-2)" "prognostic favorable (3.11e-4)" "unprognostic (1.92e-2)" "unprognostic (1.44e-1)" "unprognostic (6.22e-3)" "prognostic favorable (5.57e-4)" 26.1 15.6 45.2 5.1 61.6 14.5 7.4 25.4 91.3 17.5 23.5 5.7 3.6 14.5 18.8 9.8 15.8 13.8 6.9 60.4 24.9 20.4 3.2 8.6 5.2 29.0 36.2 14.7 7.4 10.3 25.5 4.3 31.4 22.4 5.4 18.3 4.7 24.2 2.6 4.6 5.1 15.5 24.9 7.4 6.6 26.4 39.2 3.4 20.5 4.2 4.6 14.0 18.4 55.6 2.9 4.9 155.0 4.8 4.1 3.6 5.6 3.2 2.9 2.7 1.2 3.3 4.4 7.1 5.1 1.9 3.8 9.4 1.8 4.2 4.3 4.9 4.0 5.7 7.3 4.6 3.6 2.7 3.1 4.1 1.9 3.7 5.0 5.5 3.5 4.8 5.2 27.9 1.7 3.5 4.4 3.1 8.8 0.7 3.2 4.9 4.0 2.5 10.7 16.9 9.2 8.4 3.3 5.9 2.2 5.0 8.8 3.3 7.5 6.3 6.4 3.0 2.7 8.2 5.1 4.4 9.9 3.5 3.8 3.3 0.7 1.2 0.8 0.7 1.0 1.3 0.7 1.0 0.6 1.1 1.0 1.4 4.4 1.2 0.7 1.2 1.2 0.9 45.2 61.6 25.4 91.3 60.4 24.9 29.0 36.2 31.4 24.9 39.2 55.6 4.3 22.4 33.8 902.0 1.6 0.8 15.7 5.5 4.0 26.1 3.2 3.7 1.6 8.6 12.8 22.0 6.2 0.3 0.1 0.0 11.7 2.4 219.5 61.1 25.1 1.3 2.4 0.0 1018.9 0.0 0.5 16.9 2.0 7.1 2.5 6.2 1.1 0.0 0.3 38.7 727.8 0.0 4.1 0.3 0.0 400.5 26.4 1.5 1.8 185.5 0.0 15.7 0.0 596.6 302.8 2.0 0.0 54.9 0.1 7.6 0.0 22.6 68.9 10.8 6.6 7.2 18.5 10.5 5.5 1.3 1.0 0.1 0.9 28.5 0.0 22.6 MATN2 ENSG00000132561 "Matrilin 2" O00339 8 97868840-98036724 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 201.0;Peritubular cells: 258.8;Theca cells: 297.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 5.2" "Lineage enriched" "Detected in single" 7 "T-cells: 5.2" "Cell line enhanced" "Detected in many" "BJ: 72.5;BJ hTERT+ SV40 Large T+: 78.6;BJ hTERT+ SV40 Large T+ RasG12V: 106.7;HaCaT: 114.4;HBF TERT88: 100.6;SuSa: 67.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033879 Approved "Secreted to extracellular matrix" NA NA 1500000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" "CAB033879: AB_2141502" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (9.99e-2)" "unprognostic (2.14e-1)" "unprognostic (4.98e-1)" "unprognostic (5.35e-2)" "unprognostic (7.18e-2)" "unprognostic (5.22e-2)" "unprognostic (2.77e-1)" "unprognostic (2.07e-3)" "unprognostic (1.34e-1)" "unprognostic (1.09e-1)" "unprognostic (2.04e-2)" "unprognostic (1.69e-1)" "unprognostic (6.31e-2)" "prognostic unfavorable (9.65e-4)" "unprognostic (6.65e-2)" 54.4 51.0 24.3 30.2 22.5 1.8 43.6 17.6 23.2 194.4 19.3 67.5 58.5 147.0 101.6 32.8 46.9 40.1 110.2 20.0 23.4 39.3 24.6 15.2 18.0 24.1 30.5 116.4 11.3 28.0 9.9 177.9 26.3 104.9 57.8 45.7 42.6 171.9 4.0 62.8 80.6 98.1 18.3 5.9 23.7 31.2 23.4 4.9 271.4 28.5 15.4 103.0 139.2 30.8 24.1 10.8 23.3 2.5 60.7 3.6 15.0 72.5 17.6 78.6 106.7 13.0 8.4 0.1 7.0 29.2 3.5 114.4 2.3 4.4 100.6 0.0 2.9 0.8 6.1 0.9 14.0 0.0 0.0 13.6 9.5 16.1 0.8 22.1 0.5 1.3 0.1 0.2 4.1 11.2 0.0 0.7 7.1 0.3 3.7 0.0 2.4 11.4 5.7 5.3 16.0 1.5 11.5 0.2 19.8 67.3 10.9 1.4 0.6 5.2 31.5 16.1 11.0 0.9 0.2 0.2 18.8 0.4 5.9 0.0 0.1 0.1 0.2 0.4 5.2 0.0 0.7 0.9 0.8 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 24.3 22.5 17.6 23.2 20.0 23.4 24.1 30.5 26.3 18.3 23.4 30.8 27.8 3.2 1.3 11.1 0.3 37.3 10.1 6.2 80.2 6.3 3.8 45.8 29.1 18.6 3.0 16.5 54.2 1.2 0.2 20.6 0.0 9.9 86.0 4.2 22.6 32.4 23.4 3.2 6.4 0.0 1.1 113.1 5.1 5.0 0.0 43.5 201.0 11.0 1.6 0.0 11.5 25.4 0.0 5.0 7.7 108.6 103.5 0.9 28.4 19.7 2.0 8.1 0.0 86.0 59.8 3.2 18.2 258.8 0.0 6.5 118.7 3.4 1.6 52.9 13.1 97.2 17.1 2.5 2.6 7.3 8.5 2.5 2.0 297.5 27.4 1.8 MDFI I-mfa ENSG00000112559 "MyoD family inhibitor" Q99750 6 41636882-41654244 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 44.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 221.7;Extravillous trophoblasts: 113.7;Pancreatic endocrine cells: 134.9;Syncytiotrophoblasts: 138.7;Urothelial cells: 73.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 80.5;HBEC3-KT: 117.2;OE19: 100.0;REH: 315.3" "Region enriched" "Detected in many" 7 "cerebellum: 17.0" "Low region specificity" "Detected in all" HPA049973 Approved Approved Nucleoplasm NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 14: REH - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA049973: AB_2680975" "unprognostic (9.74e-3)" "unprognostic (4.25e-2)" "unprognostic (6.82e-2)" "unprognostic (6.26e-3)" "unprognostic (9.18e-2)" "unprognostic (1.07e-1)" "unprognostic (1.69e-1)" "prognostic unfavorable (1.32e-5)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.66e-1)" "unprognostic (3.27e-2)" "unprognostic (4.04e-2)" "prognostic unfavorable (2.85e-6)" "unprognostic (2.66e-2)" "unprognostic (6.06e-2)" "unprognostic (1.57e-1)" "unprognostic (8.22e-2)" 33.0 4.3 3.9 5.7 4.2 0.2 23.1 4.1 5.8 23.2 4.3 2.5 1.7 5.8 1.2 44.7 10.0 12.8 8.8 3.5 4.3 5.5 1.5 18.6 1.7 8.2 5.8 15.6 3.2 1.6 9.1 11.0 6.3 14.3 0.4 0.1 22.4 2.2 0.9 15.4 3.2 2.5 3.6 0.3 4.6 5.0 4.6 1.5 4.6 1.1 2.5 13.6 27.1 4.2 60.1 0.2 50.4 0.1 0.1 0.0 80.5 0.0 0.0 0.0 0.0 0.0 28.2 0.1 18.2 0.0 0.3 48.4 13.8 117.2 0.0 0.0 0.0 0.4 0.0 2.5 2.2 0.0 0.3 3.6 53.3 0.6 24.6 0.0 38.4 16.1 0.2 0.3 0.0 0.0 41.8 0.4 34.4 100.0 1.6 315.3 29.6 0.5 3.3 9.2 9.4 23.2 0.6 43.1 0.0 34.5 0.2 4.0 40.3 0.1 44.1 0.5 1.7 0.1 0.3 0.1 0.3 2.8 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.2 4.1 5.8 3.5 4.3 8.2 5.8 6.3 3.6 4.6 4.2 1.8 0.0 0.0 0.0 0.0 24.5 48.6 36.8 12.0 0.5 18.9 16.9 0.9 0.0 8.2 5.5 0.0 221.7 0.2 0.4 0.0 33.8 0.5 0.5 1.7 12.7 0.0 0.0 0.1 51.2 113.7 12.8 0.0 0.7 0.0 10.0 7.9 0.1 19.6 0.0 0.3 1.2 6.1 0.0 4.5 0.5 39.1 0.4 0.0 2.8 0.6 0.0 0.0 4.5 0.2 134.9 0.0 6.0 0.0 55.6 0.0 0.0 3.5 0.0 0.0 19.7 9.1 0.1 7.9 10.7 9.1 138.7 0.6 2.7 0.3 73.5 MEIS3 "DKFZp547H236, MRG2" ENSG00000105419 "Meis homeobox 3" Q99687 19 47403124-47419527 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 102.3;endometrium 1: 77.3" "Cell type enhanced" "Detected in many" "Early spermatids: 22.4;Endometrial stromal cells: 23.5;Excitatory neurons: 39.1;Horizontal cells: 45.4;Late spermatids: 57.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 76.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046699 Uncertain Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA046699: AB_2616456" "unprognostic (3.27e-3)" "unprognostic (2.98e-1)" "unprognostic (2.13e-2)" "unprognostic (4.49e-1)" "unprognostic (3.16e-1)" "unprognostic (4.67e-2)" "unprognostic (2.12e-2)" "unprognostic (5.93e-3)" "unprognostic (1.21e-1)" "unprognostic (2.73e-2)" "unprognostic (1.58e-2)" "unprognostic (9.76e-2)" "prognostic unfavorable (1.78e-6)" "unprognostic (9.29e-3)" "unprognostic (9.21e-3)" "unprognostic (4.36e-2)" "unprognostic (3.80e-3)" 13.1 6.9 68.8 9.0 64.3 0.0 16.3 20.5 102.3 41.7 15.7 18.7 6.6 77.3 2.3 10.8 51.8 11.2 10.2 69.2 50.4 7.5 2.0 8.1 2.9 19.8 22.4 21.8 4.2 6.6 17.2 13.7 21.6 18.9 3.9 8.0 6.9 10.9 2.5 6.0 14.1 38.9 16.3 6.7 6.3 12.2 36.4 1.2 6.2 2.7 1.6 17.1 15.7 46.8 1.0 33.4 76.3 0.3 42.0 36.4 1.3 33.1 53.8 27.5 47.5 3.0 5.3 0.3 3.8 58.2 22.6 3.8 8.1 9.6 8.8 50.4 11.3 0.0 12.7 0.3 26.4 0.6 65.0 26.5 1.9 10.5 5.6 9.5 0.0 0.0 0.8 7.7 3.0 32.2 0.0 0.4 22.1 1.0 1.9 0.1 5.8 0.8 1.8 2.4 3.1 59.9 29.3 2.6 14.4 30.5 1.8 9.8 0.0 20.2 49.3 15.1 4.7 0.1 0.0 0.1 56.3 3.2 41.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.8 64.3 20.5 102.3 69.2 50.4 19.8 22.4 21.6 16.3 36.4 46.8 1.7 0.0 3.2 2.3 0.0 0.8 1.2 0.6 0.0 10.0 8.7 4.6 1.4 0.0 1.9 3.7 6.2 0.2 0.1 0.0 0.0 0.1 22.4 0.7 23.5 0.9 0.0 0.0 39.1 0.0 0.4 11.1 0.5 1.6 0.0 0.3 1.4 0.1 0.7 45.4 11.2 0.0 0.0 0.0 1.9 57.4 11.5 0.4 7.2 4.7 0.0 17.0 0.0 13.0 2.0 0.1 0.0 4.1 0.3 4.0 0.0 0.0 1.5 2.9 13.1 0.9 11.8 3.1 4.8 0.1 1.0 0.8 1.2 0.9 0.0 0.9 MEX3D "KIAA2031, OK/SW-cl.4, RKHD1, RNF193, Tino" ENSG00000181588 "Mex-3 RNA binding family member D" Q86XN8 19 1554669-1568058 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 78.3" "Cell type enriched" "Detected in many" 4 "Late spermatids: 340.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "REH: 67.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065385 Approved NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 14: REH - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" "HPA065385: AB_2685482" "unprognostic (2.71e-1)" "unprognostic (9.01e-2)" "unprognostic (3.90e-1)" "unprognostic (1.61e-2)" "unprognostic (2.04e-1)" "unprognostic (1.80e-2)" "unprognostic (9.35e-3)" "unprognostic (3.58e-2)" "unprognostic (1.89e-1)" "unprognostic (3.85e-1)" "unprognostic (3.74e-1)" "unprognostic (9.37e-3)" "unprognostic (2.75e-3)" "unprognostic (5.13e-2)" "unprognostic (2.67e-2)" "unprognostic (2.57e-1)" "unprognostic (1.36e-2)" 8.2 3.9 11.5 2.6 10.7 0.3 8.1 8.7 10.6 9.2 0.1 8.2 4.6 12.6 5.9 9.6 7.7 2.8 6.5 8.0 5.3 4.8 5.5 7.7 1.2 16.2 10.1 12.3 6.2 2.2 4.9 6.9 9.9 6.9 2.7 0.8 9.2 2.7 1.7 10.8 5.2 3.6 8.9 2.7 6.9 78.3 10.8 1.6 6.1 1.5 2.1 7.7 9.3 18.0 40.6 3.1 17.5 20.3 6.4 6.1 43.2 24.9 5.4 9.6 10.0 9.9 6.9 12.9 27.5 9.3 2.4 20.5 7.7 6.2 11.7 21.2 9.5 3.1 3.3 12.2 5.1 9.4 8.5 4.6 9.0 5.2 4.1 7.6 15.4 6.7 18.7 12.2 11.4 8.1 22.2 10.0 36.5 8.8 11.6 67.4 18.5 10.0 8.7 6.1 26.2 29.6 20.3 11.1 15.2 14.6 14.2 10.4 28.0 19.6 27.4 30.4 32.3 13.6 5.8 13.5 8.3 13.8 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 10.7 8.7 10.6 8.0 5.3 16.2 10.1 9.9 8.9 10.8 18.0 18.1 12.8 8.4 2.0 0.6 14.8 3.5 3.8 6.2 2.4 23.4 13.2 7.3 8.6 4.2 9.2 0.0 5.2 3.4 10.8 0.0 11.9 73.8 15.6 15.6 10.5 18.6 4.0 0.9 9.6 12.8 11.0 2.6 19.9 1.3 8.2 12.5 13.6 2.4 1.7 0.6 7.3 6.1 2.5 8.1 340.7 14.9 3.3 7.2 0.0 1.2 6.0 1.0 3.0 3.5 20.9 6.4 9.4 0.8 8.9 6.2 2.7 1.7 1.7 0.0 5.9 13.6 3.7 4.3 10.1 17.6 16.6 2.5 2.6 9.6 5.1 MME "CALLA, CD10, NEP" ENSG00000196549 "Membrane metalloendopeptidase" P08473 3 155024124-155183704 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, FDA approved drug targets, Neurodegeneration, Neuropathy, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 333.5;kidney: 302.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 273.3;Proximal enterocytes: 372.4;Proximal tubular cells: 125.7;Syncytiotrophoblasts: 126.0" "Cancer enhanced" "Detected in many" "prostate cancer: 17.6" "Group enriched" "Detected in many" 5 "basal ganglia: 17.3;medulla oblongata: 9.3;pons: 10.9;thalamus: 4.6" "Immune cell enriched" "Detected in some" 122 "neutrophil: 139.4" "Lineage enriched" "Detected in many" 122 "granulocytes: 139.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 684.4;BJ hTERT+: 1116.9;HSkMC: 651.1" "Region enhanced" "Detected in many" "basal ganglia: 28.1" "Group enriched" "Detected in many" 4 "basal ganglia: 32.3;olfactory bulb: 8.5;spinal cord: 15.9" "CAB000013, HPA052583, HPA056072" Enhanced NA NA 320000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "CAB000013: AB_563478, HPA052583: AB_2681872, HPA056072: AB_2683027" "unprognostic (1.36e-1)" "unprognostic (1.02e-3)" "unprognostic (8.52e-2)" "unprognostic (2.95e-1)" "unprognostic (2.78e-2)" "unprognostic (6.52e-3)" "unprognostic (1.20e-1)" "unprognostic (1.67e-2)" "unprognostic (8.67e-2)" "unprognostic (1.96e-1)" "unprognostic (7.30e-3)" "unprognostic (1.31e-1)" "unprognostic (2.71e-3)" "unprognostic (1.50e-1)" "unprognostic (7.29e-2)" "unprognostic (1.06e-2)" "unprognostic (1.37e-2)" 103.9 1.0 0.7 4.5 17.3 11.5 38.5 1.5 1.9 22.7 0.3 1.9 333.5 13.3 22.5 2.3 1.9 13.4 4.3 0.1 0.6 302.5 56.1 27.6 10.3 9.3 2.3 0.9 1.2 0.5 0.6 73.0 10.9 79.6 3.4 0.1 6.1 44.5 20.3 1.9 289.7 1.5 0.9 7.9 1.6 1.3 4.6 16.6 1.2 23.5 12.3 6.0 7.6 0.4 0.1 0.0 0.9 0.3 280.1 684.4 1.6 160.3 1116.9 82.2 209.8 0.0 0.3 172.9 0.1 130.1 107.4 0.5 5.2 6.1 201.3 0.0 0.8 0.0 0.1 0.2 229.6 0.0 0.0 651.1 1.0 40.4 308.1 89.4 59.5 0.4 0.2 0.3 135.1 0.7 0.4 1.0 6.1 0.5 1.1 303.3 139.9 1.6 5.2 1.9 0.5 1.5 0.1 0.5 31.9 68.3 0.2 0.2 165.8 356.4 0.8 115.7 27.9 0.1 0.0 217.3 42.5 0.1 7.3 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 139.4 0.0 0.0 1.1 0.0 0.0 0.7 17.3 1.5 1.9 0.1 0.6 9.3 2.3 10.9 0.9 4.6 0.4 5.9 9.6 13.0 0.3 2.3 0.8 74.1 2.5 0.0 0.0 1.5 64.1 1.6 21.5 11.2 22.0 0.0 82.1 6.9 0.0 9.8 0.2 0.5 6.2 273.3 6.6 0.0 0.0 2.2 0.0 57.8 40.6 0.0 5.7 2.5 0.0 2.9 53.2 8.9 0.0 8.1 9.9 2.0 3.1 1.2 0.5 4.1 10.7 0.0 0.0 0.2 0.0 0.0 0.5 0.3 0.6 13.8 1.2 0.1 40.0 372.4 125.7 1.6 0.0 0.0 17.4 11.1 0.2 0.5 0.1 0.3 126.0 2.5 0.1 12.6 33.6 MMP16 "C8orf57, DKFZp761D112, MT3-MMP" ENSG00000156103 "Matrix metallopeptidase 16" P51512 8 88032011-88328025 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 2402.1" "Cancer enhanced" "Detected in many" "glioma: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 29.4;HUVEC TERT2: 12.8;SH-SY5Y: 16.2;U-138 MG: 13.7;WM-115: 28.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023693 Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol Vesicles "HPA023693: AB_1854025" "unprognostic (2.58e-1)" "unprognostic (2.42e-2)" "unprognostic (1.38e-1)" "unprognostic (1.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.31e-2)" "unprognostic (2.39e-3)" "unprognostic (1.45e-3)" "unprognostic (2.46e-1)" "unprognostic (2.61e-1)" "unprognostic (9.42e-2)" "unprognostic (2.92e-1)" "unprognostic (2.09e-8)" "unprognostic (6.90e-3)" "unprognostic (1.16e-1)" "unprognostic (3.62e-1)" "unprognostic (2.19e-3)" 0.7 0.3 4.6 0.3 5.8 0.0 1.8 2.2 5.4 1.7 0.0 0.8 0.1 1.6 0.6 0.4 0.6 2.6 0.8 5.1 3.9 0.1 0.1 0.2 0.2 1.0 1.5 1.0 0.6 0.2 0.5 1.0 1.3 0.9 0.4 0.4 0.3 0.7 0.1 0.2 0.3 1.3 1.4 0.4 0.3 0.4 3.0 0.4 1.0 0.5 0.2 0.9 0.5 3.3 0.0 0.2 7.9 29.4 1.0 2.0 0.0 10.9 1.6 3.0 1.8 0.0 0.1 0.0 0.0 4.9 1.8 0.0 5.8 0.0 3.7 0.0 3.4 0.0 0.0 0.0 2.4 0.0 0.5 1.4 0.0 4.4 1.3 5.4 12.8 0.1 0.0 1.1 1.7 0.0 0.0 0.0 1.7 0.0 3.0 0.3 0.6 0.0 0.6 0.1 0.2 16.2 0.0 0.0 0.2 2.2 1.1 0.0 7.1 13.7 7.7 0.2 4.2 0.0 0.0 0.0 5.7 0.0 28.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 5.8 2.2 5.4 5.1 3.9 1.0 1.5 1.3 1.4 3.0 3.3 2.2 0.0 0.0 20.5 0.1 1.1 0.0 0.0 0.6 4.4 0.8 1.4 1.0 0.0 0.0 0.0 2.1 0.1 0.1 0.0 1.9 0.0 6.5 0.5 15.9 5.2 0.0 0.0 443.4 0.0 0.1 16.0 0.0 0.4 0.0 1.9 1.4 0.0 0.4 1.7 300.3 0.0 0.0 0.0 1.6 6.5 0.9 0.4 1.8 10.3 0.0 3.0 0.0 2402.1 13.0 0.1 0.0 1.2 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.7 2.9 0.0 1.1 0.2 0.1 0.0 0.2 3.4 0.0 0.1 MMP17 MT4-MMP ENSG00000198598 "Matrix metallopeptidase 17" Q9ULZ9 12 131828393-131851783 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.2" "Group enriched" "Detected in many" 5 "Excitatory neurons: 47.0;Inhibitory neurons: 14.3;Melanocytes: 28.4;Oligodendrocyte precursor cells: 26.7" "Cancer enriched" "Detected in many" 10 "melanoma: 29.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "REH: 29.6;SK-MEL-30: 60.4;WM-115: 87.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA "Cluster 37: B-cells - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (9.11e-2)" "unprognostic (1.27e-2)" "unprognostic (1.69e-2)" "unprognostic (3.71e-3)" "unprognostic (5.62e-2)" "unprognostic (1.85e-2)" "unprognostic (8.90e-3)" "unprognostic (2.14e-2)" "unprognostic (2.60e-1)" "unprognostic (2.66e-4)" "unprognostic (7.68e-2)" "unprognostic (5.88e-2)" "unprognostic (9.26e-10)" "unprognostic (1.15e-2)" "unprognostic (2.65e-1)" "unprognostic (1.21e-3)" "unprognostic (2.81e-2)" 3.9 0.8 9.9 1.2 16.6 0.9 4.0 0.0 37.2 10.8 0.0 6.4 0.3 3.7 0.0 1.7 2.4 1.0 2.2 31.7 9.2 1.0 1.0 2.0 0.9 0.0 0.2 11.6 2.0 0.1 1.5 0.1 0.3 2.9 0.1 0.1 3.1 0.5 0.9 4.7 2.7 0.3 0.0 1.7 1.6 3.2 6.3 0.0 1.7 0.0 0.2 2.7 4.7 8.8 0.3 11.5 0.0 0.5 2.3 2.9 0.1 7.2 7.9 2.1 3.3 0.0 1.4 0.0 5.2 1.8 1.4 3.8 1.3 1.5 0.0 0.0 0.7 1.1 3.8 0.0 3.6 0.0 7.2 2.7 1.2 2.4 0.0 0.5 4.0 0.0 2.0 0.0 1.0 8.3 0.0 11.5 4.6 1.6 7.3 29.6 0.0 3.9 0.0 0.0 3.7 2.0 1.0 0.2 60.4 0.5 7.4 12.8 5.8 0.7 0.9 6.3 0.6 0.0 0.0 0.0 2.4 0.3 87.5 0.0 0.4 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 9.9 16.6 0.0 37.2 31.7 9.2 0.0 0.2 0.3 0.0 6.3 8.8 0.6 0.0 0.0 2.9 2.3 2.5 0.1 1.7 0.6 1.0 2.3 1.8 1.2 1.5 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 5.4 0.5 0.0 0.0 47.0 0.2 0.2 5.4 0.0 0.4 0.0 0.7 1.1 0.0 0.6 3.3 14.3 0.0 2.0 2.6 1.0 0.4 0.9 3.4 28.4 3.7 2.4 0.1 0.0 26.7 2.9 0.0 0.0 1.9 0.0 0.2 0.0 0.4 0.2 0.1 0.0 0.8 1.4 0.4 0.4 0.1 1.1 0.0 0.2 5.3 0.0 0.2 MORC4 "FLJ11565, ZCW4, ZCWCC2" ENSG00000133131 "MORC family CW-type zinc finger 4" Q8TE76 X 106813871-107000212 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 79.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 131.4;Alveolar cells type 2: 130.4;Cytotrophoblasts: 329.8;Syncytiotrophoblasts: 257.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 121.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000395, HPA015547, HPA050250" Enhanced Enhanced Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA000395: AB_1079405, HPA015547: AB_2669216, HPA050250: AB_2681063" "prognostic unfavorable (3.56e-5)" "unprognostic (3.30e-3)" "unprognostic (1.09e-1)" "unprognostic (1.13e-1)" "unprognostic (1.40e-1)" "unprognostic (6.29e-3)" "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "unprognostic (1.47e-1)" "unprognostic (2.30e-2)" "unprognostic (5.56e-2)" "unprognostic (8.59e-2)" "unprognostic (1.60e-1)" "unprognostic (1.60e-2)" "unprognostic (6.57e-2)" "unprognostic (4.89e-2)" "unprognostic (8.69e-2)" 13.4 30.9 24.8 7.8 35.5 11.8 12.2 47.8 51.0 12.1 17.8 8.5 10.4 11.5 16.3 9.6 10.4 10.1 7.0 32.4 22.4 10.8 21.1 8.8 5.6 11.1 11.4 17.4 15.1 11.7 6.2 79.9 16.6 12.4 10.8 22.3 10.9 11.5 20.2 18.7 10.0 11.4 3.9 6.0 8.4 20.2 16.6 5.6 10.2 10.3 7.0 7.5 11.1 55.7 29.8 121.0 11.4 26.4 35.0 40.3 60.5 28.7 30.8 14.6 18.3 64.6 13.1 3.7 14.2 30.5 23.9 22.5 39.8 25.5 17.1 4.6 23.0 6.4 40.7 27.1 25.6 4.7 13.9 20.8 24.3 19.6 28.6 85.7 13.1 4.1 3.9 41.4 32.7 26.7 10.7 6.4 8.9 82.0 45.2 4.2 22.9 4.3 47.0 23.3 9.2 11.5 35.4 33.9 23.0 15.9 19.7 5.0 12.6 22.5 21.4 44.7 15.7 11.1 16.2 11.5 24.0 3.8 16.2 8.3 1.5 1.8 1.9 1.3 1.7 1.7 1.9 1.5 0.7 2.7 2.1 1.7 3.7 1.5 1.7 2.5 1.5 0.4 24.8 35.5 47.8 51.0 32.4 22.4 11.1 11.4 16.6 3.9 16.6 55.7 8.6 131.4 130.4 6.2 5.1 17.5 19.1 4.9 21.1 5.4 11.5 9.5 3.0 10.0 61.8 5.5 4.2 329.8 10.4 3.6 21.5 9.9 0.9 6.2 11.5 13.6 1.8 0.4 4.2 7.4 28.2 33.4 10.2 15.5 66.3 10.3 7.5 24.0 23.4 1.7 6.5 10.5 6.1 2.1 5.0 1.8 11.1 8.2 12.4 3.7 0.3 6.7 3.1 15.1 8.7 7.5 6.7 11.7 5.8 16.4 4.4 12.7 62.2 7.2 26.3 16.9 12.0 9.9 26.6 19.7 16.1 257.8 11.9 10.1 10.1 11.8 MTMR11 CRA ENSG00000014914 "Myotubularin related protein 11" A4FU01 1 149928651-149936879 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 139.2;Intestinal goblet cells: 79.2;Paneth cells: 98.9;Proximal enterocytes: 133.2;Undifferentiated cells: 56.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.3;myeloid DC: 1.7;non-classical monocyte: 1.3" "Group enriched" "Detected in many" 16 "dendritic cells: 1.7;monocytes: 1.3" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 17.0;OE19: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030351, HPA072906" Enhanced Approved Centrosome NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Centrosome "HPA030351: AB_10602185, HPA072906: " "unprognostic (1.14e-1)" "unprognostic (3.01e-3)" "unprognostic (1.42e-1)" "unprognostic (1.22e-2)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (1.37e-2)" "unprognostic (5.81e-2)" "unprognostic (7.94e-2)" "unprognostic (2.98e-1)" "unprognostic (2.88e-2)" "unprognostic (1.22e-1)" "unprognostic (5.83e-2)" "unprognostic (1.83e-1)" "unprognostic (5.67e-2)" "unprognostic (1.80e-2)" "unprognostic (9.12e-2)" 3.6 12.3 3.5 2.9 3.6 0.1 4.1 3.2 4.0 11.0 7.3 22.2 20.3 9.5 6.9 4.3 8.4 12.9 3.2 3.1 3.9 6.9 1.4 3.8 0.7 5.1 4.3 15.2 2.1 5.1 5.3 4.2 3.9 4.7 26.7 1.0 2.2 7.7 1.0 9.4 23.4 13.8 4.5 1.8 3.9 4.9 3.8 0.7 1.6 2.7 0.9 6.9 6.9 4.4 3.1 7.3 3.1 2.6 8.6 10.1 6.6 3.1 10.0 4.0 4.9 0.2 12.9 0.0 6.7 10.6 4.9 4.3 0.3 5.2 2.4 0.2 0.1 0.0 2.3 0.9 2.2 0.0 0.2 6.3 1.7 4.1 6.8 17.0 4.8 0.1 0.2 0.3 7.8 9.9 0.0 0.1 0.7 20.5 2.9 0.0 1.0 0.1 5.8 0.9 0.2 0.2 1.7 2.9 1.1 2.0 3.0 0.0 3.3 4.5 5.4 4.0 2.7 0.6 1.5 0.0 3.9 0.0 0.5 0.0 0.8 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 3.5 3.6 3.2 4.0 3.1 3.9 5.1 4.3 3.9 4.5 3.8 4.4 2.2 0.0 0.6 2.6 0.5 4.1 3.8 8.9 5.2 0.0 3.0 4.1 6.4 5.7 3.6 14.7 0.0 14.1 0.4 139.2 1.9 15.0 0.6 1.7 3.1 4.5 15.7 0.0 4.0 17.0 10.7 7.0 19.4 2.2 0.0 3.0 3.9 1.5 4.8 0.0 4.9 79.2 0.0 11.3 6.1 0.3 5.6 15.7 1.8 1.0 43.8 0.0 0.0 0.0 3.6 45.1 98.9 12.0 0.3 4.9 133.2 18.5 4.5 0.0 6.6 0.5 7.3 0.4 0.6 3.4 6.5 28.5 0.9 6.4 56.5 4.1 MXRA5 DKFZp564I1922 ENSG00000101825 "Matrix remodeling associated 5" Q9NR99 X 3308565-3346652 "Cancer-related genes, Disease related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 35.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 38.5;Collecting duct cells: 31.3;Exocrine glandular cells: 60.7;Fibroblasts: 56.0;Pancreatic endocrine cells: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 31.4;BJ hTERT+: 125.8;fHDF/TERT166: 59.8;HaCaT: 52.4;HSkMC: 24.7" "Low region specificity" "Detected in all" "HPA000508, HPA076518" Uncertain Uncertain Mitochondria "Secreted to extracellular matrix" NA NA 2600000 "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA000508: AB_2147995, HPA076518: " "unprognostic (7.51e-2)" "unprognostic (6.45e-2)" "unprognostic (8.00e-2)" "unprognostic (2.51e-2)" "prognostic unfavorable (1.81e-4)" "unprognostic (7.05e-2)" "unprognostic (7.25e-2)" "unprognostic (1.35e-2)" "unprognostic (1.13e-1)" "unprognostic (2.53e-2)" "unprognostic (6.32e-3)" "unprognostic (1.38e-1)" "unprognostic (1.65e-2)" "unprognostic (1.58e-1)" "unprognostic (1.90e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (8.94e-4)" 12.0 10.3 0.2 9.4 0.3 0.0 13.5 0.0 0.4 35.0 0.0 7.5 4.4 6.8 2.7 9.4 3.0 8.0 11.1 0.2 0.1 5.3 4.5 5.3 1.6 0.3 0.3 2.9 16.1 1.7 0.9 5.8 0.2 7.3 10.4 0.0 6.1 10.4 1.5 29.6 4.6 15.9 0.5 3.6 10.3 0.1 1.2 5.7 9.8 5.1 3.7 19.9 7.2 0.1 0.0 0.0 0.8 0.0 0.2 31.4 0.0 19.6 125.8 0.2 0.2 0.0 0.6 0.0 1.7 59.8 0.2 52.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 24.7 5.9 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 2.0 1.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.4 0.2 0.1 0.3 0.3 0.2 0.5 1.2 0.1 10.3 0.0 0.0 0.0 0.0 38.5 7.1 10.5 20.5 0.0 2.0 4.6 1.9 0.0 3.7 31.3 0.0 0.1 0.3 0.9 0.0 2.2 0.0 1.0 8.4 4.6 0.0 0.0 0.7 60.7 0.7 56.0 0.0 1.6 0.0 0.0 10.8 0.1 0.3 0.0 1.1 0.0 0.0 0.3 16.9 0.0 0.0 0.3 17.8 4.7 0.6 0.0 0.0 0.5 0.2 42.8 0.0 1.5 0.1 0.2 0.1 0.1 1.0 0.2 0.0 7.3 9.8 0.0 0.0 5.5 21.7 0.3 1.1 0.9 0.4 2.0 MYO15A "DFNB3, MYO15" ENSG00000091536 "Myosin XVA" Q9UKN7 17 18108706-18179802 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Hearing "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "pituitary gland: 62.9" "Group enriched" "Detected in many" 4 "Early spermatids: 69.9;Late spermatids: 53.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 4 "basophil: 1.4" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078501 Enhanced NA NA "Cluster 34: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 29: Early spermatids - Spermatogenesis" "HPA078501: AB_2732383" "unprognostic (2.48e-3)" "unprognostic (5.31e-2)" "unprognostic (2.87e-3)" "unprognostic (7.35e-3)" "unprognostic (4.92e-3)" "unprognostic (2.33e-1)" "unprognostic (8.32e-4)" "unprognostic (4.51e-2)" "unprognostic (1.51e-1)" "unprognostic (1.24e-1)" "unprognostic (4.66e-3)" "unprognostic (8.38e-2)" "unprognostic (4.18e-3)" "unprognostic (5.69e-3)" "unprognostic (9.89e-2)" "unprognostic (1.47e-1)" "unprognostic (2.21e-2)" 0.5 0.4 0.5 0.3 0.4 0.1 0.6 0.5 1.5 1.3 0.0 0.7 0.3 1.0 1.5 0.3 1.4 0.2 0.6 0.0 0.6 0.6 1.9 0.9 0.1 1.8 0.5 2.2 0.5 0.8 62.9 0.1 2.1 0.9 0.3 0.3 0.6 0.9 0.4 0.3 0.6 0.2 0.5 0.5 0.6 7.2 1.4 0.8 0.9 0.0 0.2 0.7 0.8 0.4 0.0 0.0 0.4 0.0 0.2 0.7 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.1 1.4 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.5 0.4 0.5 1.5 0.0 0.6 1.8 0.5 2.1 0.5 1.4 0.4 0.3 0.0 1.1 0.7 0.8 1.5 2.1 0.2 1.2 2.9 0.9 0.6 4.0 1.5 0.1 0.0 0.0 0.5 0.3 0.7 0.0 0.8 69.9 0.8 0.9 1.0 4.2 0.0 8.5 0.9 0.3 1.4 0.5 1.2 6.3 1.3 0.4 1.7 0.6 10.1 4.5 0.5 0.0 0.8 1.4 53.6 1.2 0.8 3.6 1.0 1.3 2.6 2.1 1.5 0.9 0.6 0.1 1.2 0.1 1.9 0.4 0.3 0.2 2.5 0.0 4.6 1.1 9.2 13.4 0.4 1.3 0.7 0.6 0.7 0.8 1.0 NDUFA4L2 "COXFA4L2, FLJ26118, NUOMS" ENSG00000185633 "NDUFA4 mitochondrial complex associated like 2" Q9NRX3 12 57234903-57240715 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 304.9" "Group enriched" "Detected in many" 4 "Muller glia cells: 627.0;Sertoli cells: 1130.7;Smooth muscle cells: 525.6" "Cancer enriched" "Detected in all" 5 "renal cancer: 356.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 7 "AN3-CA: 133.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055323, HPA078265" Uncertain Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria "HPA055323: , HPA078265: " "unprognostic (1.25e-1)" "unprognostic (1.60e-1)" "unprognostic (2.11e-3)" "unprognostic (3.23e-3)" "unprognostic (5.06e-2)" "unprognostic (1.22e-2)" "unprognostic (2.25e-2)" "unprognostic (3.53e-1)" "unprognostic (6.67e-2)" "unprognostic (5.79e-2)" "unprognostic (2.13e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (1.37e-5)" "unprognostic (9.10e-3)" "unprognostic (1.31e-1)" "unprognostic (6.41e-2)" "unprognostic (2.74e-2)" 85.6 14.0 41.6 6.8 40.1 0.2 55.1 41.4 61.5 109.3 36.8 17.4 5.8 20.7 2.4 304.9 15.5 17.1 180.1 40.3 41.1 47.6 20.9 62.6 5.8 43.0 42.7 14.0 14.5 12.1 30.9 71.7 48.8 27.3 1.9 29.4 55.8 9.8 43.8 206.9 14.2 7.5 38.9 74.1 18.0 8.7 43.5 3.2 54.5 29.2 4.8 27.7 183.5 45.4 0.9 1.3 0.3 133.9 5.4 3.1 0.4 2.1 1.5 0.6 1.3 0.0 1.5 5.5 5.6 2.1 0.1 1.2 0.7 1.0 0.0 3.0 0.2 0.6 0.3 0.1 18.6 4.1 2.0 12.0 2.5 0.2 4.7 0.9 0.0 7.6 0.5 7.2 0.4 2.7 1.1 0.2 0.3 0.6 2.4 2.1 1.0 11.0 0.1 0.1 7.1 2.5 0.2 0.3 4.7 0.1 1.5 14.5 0.6 1.2 0.1 1.1 0.7 10.0 3.5 2.5 4.9 9.8 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 41.6 40.1 41.4 61.5 40.3 41.1 43.0 42.7 48.8 38.9 43.5 45.4 156.0 0.0 0.5 2.6 2.6 151.2 0.9 89.2 6.8 30.6 2.6 5.8 1.2 0.0 24.8 0.0 18.8 1.0 0.9 0.1 0.0 1.6 1.7 0.4 3.0 91.8 0.0 0.0 2.2 0.0 1.5 21.5 4.6 0.3 8.9 0.1 2.9 1.3 1.9 11.8 3.0 0.2 54.9 0.0 28.9 3.0 3.1 2.0 30.2 18.7 1.0 627.0 0.0 0.5 0.4 4.7 0.0 2.2 1.4 2.0 0.1 0.3 6.2 25.7 1130.7 13.0 525.6 12.3 5.5 20.3 161.4 1.1 1.9 2.5 0.2 1.4 NEGR1 "IGLON4, KILON, MGC46680, Ntra" ENSG00000172260 "Neuronal growth regulator 1" Q7Z3B1 1 71395943-72282539 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 29.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 1968.8;Inhibitory neurons: 1254.4;Oligodendrocyte precursor cells: 726.3;Oligodendrocytes: 442.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 26.7;TIME: 28.5;U-2 OS: 22.9;U-251 MG: 24.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011894 Uncertain Approved "Vesicles,Actin filaments,Cytosol" NA NA 380000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Actin filaments, Cytosol" "HPA011894: AB_1854363" "unprognostic (2.60e-1)" "unprognostic (1.89e-2)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "unprognostic (7.99e-2)" "unprognostic (2.48e-1)" "unprognostic (3.72e-1)" "unprognostic (6.94e-2)" "unprognostic (8.15e-2)" "unprognostic (8.73e-2)" "unprognostic (3.38e-2)" "unprognostic (1.36e-1)" "unprognostic (3.31e-5)" "unprognostic (5.89e-3)" "unprognostic (1.31e-1)" "unprognostic (1.43e-3)" "unprognostic (2.11e-4)" 16.5 5.8 12.8 3.6 15.9 1.2 5.9 4.4 15.7 7.1 0.0 17.5 2.7 5.2 4.1 10.5 7.2 10.7 11.2 15.1 9.1 6.8 0.3 5.5 1.6 1.9 5.6 6.0 4.5 0.7 3.9 2.9 2.7 7.3 7.8 29.8 2.4 5.4 3.3 5.8 5.1 6.4 3.7 0.6 7.4 3.2 12.4 5.6 3.5 5.1 0.8 13.3 6.6 6.5 0.4 0.1 0.8 0.2 26.7 21.0 0.2 19.4 7.2 10.4 12.7 0.1 0.2 0.3 0.1 21.5 0.2 0.6 0.0 0.0 22.4 0.2 0.1 0.1 3.4 0.1 2.2 0.2 0.4 10.2 0.1 8.9 1.5 15.4 12.5 0.3 0.1 0.8 19.5 0.1 0.2 0.2 3.2 0.3 11.0 13.7 20.4 0.3 1.7 0.3 1.5 1.7 6.8 0.1 0.0 0.4 0.1 0.3 28.5 2.3 22.9 0.9 24.5 0.4 0.2 0.1 5.2 13.0 8.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 12.8 15.9 4.4 15.7 15.1 9.1 1.9 5.6 2.7 3.7 12.4 6.5 6.0 0.0 0.5 170.7 0.0 5.0 0.6 0.1 0.0 51.4 0.2 0.5 4.2 1.5 2.5 0.0 27.1 0.0 4.4 0.1 0.0 2.4 6.2 0.1 1.3 2.6 0.0 0.8 1968.8 0.0 0.0 88.7 0.5 0.1 0.0 0.2 0.0 0.0 0.2 1.7 1254.4 0.6 0.0 0.0 16.7 12.5 210.3 2.4 8.8 58.1 3.1 12.2 0.0 726.3 442.7 0.5 0.0 44.8 0.5 1.3 0.0 1.5 7.1 58.7 32.9 8.3 8.5 0.7 2.5 0.3 3.4 0.0 1.1 0.2 0.1 0.7 NKD2 Naked2 ENSG00000145506 "NKD inhibitor of WNT signaling pathway 2" Q969F2 5 1008802-1038943 "Predicted intracellular proteins" "Exocytosis, Transport, Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 42.1" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 6.8;Fibroblasts: 11.6;Langerhans cells: 7.1;Melanocytes: 7.2;Microglial cells: 7.5;Muller glia cells: 7.1;Spermatogonia: 11.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 24.4;HEK 293: 14.4;MOLT-4: 7.3;NB-4: 13.4;REH: 8.8;RPMI-8226: 22.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049463 Uncertain NA NA "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA049463: AB_2680777" "unprognostic (6.23e-3)" "unprognostic (2.82e-1)" "unprognostic (4.38e-1)" "unprognostic (1.47e-1)" "unprognostic (3.18e-2)" "unprognostic (6.24e-3)" "unprognostic (5.87e-3)" "unprognostic (4.43e-1)" "prognostic unfavorable (9.97e-4)" "unprognostic (3.35e-2)" "unprognostic (6.86e-2)" "unprognostic (1.04e-2)" "prognostic unfavorable (2.66e-5)" "unprognostic (2.36e-1)" "unprognostic (1.48e-1)" "unprognostic (2.81e-2)" "unprognostic (1.52e-1)" 4.7 5.1 0.7 0.2 1.3 0.0 3.8 0.0 2.4 1.6 0.0 4.0 0.1 1.1 0.0 8.5 3.1 0.1 5.5 2.4 0.0 6.9 3.1 42.1 0.0 0.6 0.0 1.3 4.2 0.1 2.0 0.4 0.0 6.1 0.0 0.1 4.9 0.0 0.3 9.6 3.5 0.0 0.0 15.3 2.4 8.0 0.0 0.9 2.3 0.0 0.1 3.8 2.5 0.1 0.0 0.2 0.5 0.2 0.0 0.0 24.4 0.0 0.0 0.0 0.0 1.5 0.2 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 14.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.7 0.0 0.0 1.2 7.3 13.4 0.2 1.9 0.0 8.8 0.0 22.1 0.0 1.7 0.2 0.0 0.2 0.0 1.2 0.1 0.0 2.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.3 0.0 2.4 2.4 0.0 0.6 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 6.1 2.8 0.5 4.6 0.2 0.8 1.9 3.3 2.8 0.1 0.0 2.1 0.1 0.2 0.0 0.0 2.9 0.6 2.1 6.8 2.0 0.0 0.0 1.5 0.0 0.1 11.6 0.0 0.5 0.0 0.0 0.7 0.0 0.3 1.7 1.4 0.0 0.0 0.0 7.1 1.3 0.3 0.5 7.2 7.5 0.0 7.1 0.0 0.0 0.2 0.1 0.0 0.4 0.1 2.7 0.0 2.0 0.0 0.1 0.0 0.1 1.9 1.0 11.3 0.5 5.7 0.0 1.3 0.0 0.0 1.2 NOVA1 NOVA-1 ENSG00000139910 "NOVA alternative splicing regulator 1" P51513 14 26443090-26598033 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 222.9;Excitatory neurons: 414.9;Oligodendrocyte precursor cells: 1269.7;Oligodendrocytes: 319.5" "Cancer enriched" "Detected in many" 5 "glioma: 14.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 53.3;ASC diff: 25.6;HAP1: 23.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004155 Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoli Nucleoplasm "HPA004155: AB_1079497" "unprognostic (1.46e-1)" "unprognostic (4.43e-3)" "unprognostic (6.55e-3)" "unprognostic (4.00e-2)" "unprognostic (6.69e-3)" "unprognostic (4.29e-2)" "unprognostic (3.74e-3)" "unprognostic (2.41e-1)" "unprognostic (5.21e-1)" "unprognostic (4.32e-2)" "unprognostic (5.04e-4)" "unprognostic (2.40e-1)" "unprognostic (1.93e-3)" "unprognostic (9.27e-4)" "unprognostic (9.20e-2)" "unprognostic (5.62e-2)" "unprognostic (1.31e-4)" 23.4 5.4 44.0 2.4 39.7 0.1 28.9 85.4 56.3 12.1 18.9 11.6 1.4 8.5 4.9 2.9 6.7 4.8 3.3 38.8 65.3 6.1 0.9 1.4 3.4 50.3 51.2 5.0 1.2 2.4 19.3 0.1 48.5 5.6 5.1 13.4 2.7 15.9 4.3 4.7 3.6 9.5 49.2 0.9 3.3 8.8 71.1 1.2 3.4 8.7 4.5 5.9 8.4 45.5 0.0 11.6 53.3 0.0 25.6 14.6 0.1 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.7 0.7 7.1 0.1 23.7 0.2 0.0 0.0 1.8 0.0 0.1 0.3 8.5 0.0 2.1 16.8 0.0 3.6 2.9 17.8 10.3 8.7 0.0 0.1 8.4 0.0 9.8 0.1 13.5 0.0 10.9 1.3 14.8 0.2 6.8 9.1 15.5 9.4 0.0 0.0 0.0 4.2 1.1 0.0 0.0 6.5 7.7 5.2 1.4 0.0 0.0 0.0 8.8 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 44.0 39.7 85.4 56.3 38.8 65.3 50.3 51.2 48.5 49.2 71.1 45.5 24.8 0.0 1.5 141.0 0.2 5.2 5.9 0.0 4.6 222.9 51.5 29.6 1.1 5.7 0.0 14.7 4.2 0.1 1.4 6.6 9.8 0.4 20.1 0.6 15.0 9.4 65.9 0.0 414.9 0.4 0.0 188.8 0.5 0.2 0.0 18.2 38.6 0.5 0.2 136.3 203.5 7.1 0.0 0.6 10.5 16.5 150.4 2.1 3.6 93.7 0.0 32.3 0.0 1269.7 319.5 2.0 11.7 65.8 1.9 6.7 0.3 30.3 4.4 12.0 6.6 28.6 17.7 163.1 64.3 0.7 3.1 0.0 1.5 30.0 8.4 0.6 NRK DKFZp686A17109 ENSG00000123572 "Nik related kinase" Q7Z2Y5 X 105822539-105958610 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 16.1;ovary: 32.5;placenta: 24.2" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 79.4;Leydig cells: 113.4;Syncytiotrophoblasts: 67.9;Theca cells: 70.2" "Cancer enriched" "Detected in some" 8 "testis cancer: 6.1" "Region enriched" "Detected in single" 11 "cerebellum: 7.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 58.1;HSkMC: 10.6;RH-30: 12.8;RPTEC TERT1: 34.8;SuSa: 40.5" "Region enriched" "Detected in single" 28 "cerebellum: 14.2" "Region enhanced" "Detected in all" "cerebellum: 41.6" HPA017238 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Cytosol" "HPA017238: AB_1854645" "unprognostic (2.64e-4)" "unprognostic (9.82e-2)" "unprognostic (5.98e-3)" "unprognostic (5.52e-2)" "unprognostic (3.87e-2)" "unprognostic (2.29e-2)" "unprognostic (1.12e-1)" "unprognostic (2.86e-2)" "unprognostic (1.35e-2)" "unprognostic (6.08e-2)" "unprognostic (3.24e-2)" "unprognostic (5.28e-3)" "unprognostic (1.47e-3)" "unprognostic (1.14e-1)" "unprognostic (4.28e-2)" "unprognostic (6.80e-3)" 0.8 16.1 0.0 0.9 0.0 0.0 0.7 7.0 0.3 1.8 0.0 1.4 0.1 1.7 4.6 0.6 0.9 10.1 3.5 0.0 0.1 6.2 0.1 0.2 0.0 0.1 0.6 32.5 0.4 0.1 0.3 24.2 0.5 4.9 0.3 0.1 1.1 0.9 0.2 0.1 0.3 1.7 0.1 0.0 0.5 3.3 0.0 0.1 0.2 3.3 0.0 1.0 0.6 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 10.6 0.0 0.1 0.0 3.5 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 12.8 0.0 34.8 0.7 0.0 0.2 0.0 1.8 0.0 40.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.3 0.0 0.1 0.1 0.6 0.5 0.1 0.0 0.4 3.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.6 0.0 1.2 1.0 4.8 0.0 0.0 0.0 0.0 79.4 0.0 0.2 19.6 0.2 1.3 0.0 3.2 0.7 0.0 0.0 0.9 0.0 10.1 8.9 0.0 0.0 0.0 2.1 0.0 0.0 7.1 0.0 0.9 0.0 0.0 0.0 0.0 2.6 113.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 13.5 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.1 0.7 1.6 1.7 0.1 0.0 67.9 0.0 70.2 0.2 0.1 NRXN2 ENSG00000110076 "Neurexin 2" "P58401, Q9P2S2" 11 64606174-64723197 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 72.4;Horizontal cells: 149.7;Inhibitory neurons: 47.8;Late spermatids: 49.7;Muller glia cells: 60.7;Oligodendrocyte precursor cells: 47.3;Peritubular cells: 59.0" "Cancer enhanced" "Detected in many" "glioma: 12.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 47.8;SCLC-21H: 22.8;SH-SY5Y: 10.5;U-2 OS: 26.1;U-87 MG: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 1000000 "Cluster 7: Monocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 14: REH - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (3.87e-2)" "unprognostic (1.54e-4)" "unprognostic (2.60e-2)" "unprognostic (1.96e-1)" "unprognostic (8.07e-2)" "unprognostic (2.51e-2)" "unprognostic (1.89e-1)" "unprognostic (1.80e-1)" "unprognostic (5.08e-2)" "unprognostic (3.23e-1)" "unprognostic (5.93e-3)" "unprognostic (3.40e-1)" "unprognostic (9.97e-3)" "unprognostic (2.39e-2)" "unprognostic (6.99e-2)" "unprognostic (4.27e-4)" "unprognostic (5.46e-3)" 3.8 4.7 61.0 2.0 51.6 0.5 2.6 73.6 65.9 27.0 0.0 17.1 1.0 19.0 1.1 0.4 14.6 2.2 3.7 61.9 21.8 5.8 1.0 1.5 1.0 16.0 18.2 15.5 3.0 0.1 4.3 0.7 11.6 4.9 0.6 13.0 1.6 2.9 1.1 0.9 2.7 2.4 4.6 1.5 2.4 15.3 24.8 0.8 4.0 0.3 0.4 5.9 7.4 18.3 0.0 0.0 2.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 2.1 0.0 0.3 0.3 2.5 2.0 0.1 3.3 0.0 0.0 0.3 0.4 6.5 0.0 0.0 0.0 0.0 0.5 1.2 0.0 4.5 0.0 0.0 0.0 0.1 0.0 9.0 3.1 0.0 0.7 0.3 7.6 0.0 0.0 47.8 1.4 1.9 0.0 0.0 22.8 10.5 0.1 0.0 0.0 0.1 0.0 0.0 0.3 1.1 26.1 0.5 0.0 0.0 0.0 0.0 18.6 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 61.0 51.6 73.6 65.9 61.9 21.8 16.0 18.2 11.6 4.6 24.8 18.3 0.5 0.0 0.0 13.1 0.0 0.5 0.1 0.0 0.0 72.4 0.2 0.6 3.2 0.0 0.0 1.8 6.2 0.1 0.6 6.3 3.9 0.0 23.6 0.9 23.5 2.5 6.7 2.1 36.0 2.7 0.2 7.3 0.0 0.6 0.0 0.7 2.9 8.6 0.2 149.7 47.8 1.1 0.0 1.2 0.7 49.7 42.6 1.2 0.0 7.5 0.7 60.7 6.2 47.3 26.0 0.4 2.5 59.0 0.0 0.1 5.1 40.9 0.0 21.7 0.0 27.3 4.0 37.5 15.2 0.0 0.1 0.3 0.7 4.9 0.9 0.0 NUDT11 "DIPP3b, FLJ10628, hDIPP3beta" ENSG00000196368 "Nudix hydrolase 11" Q96G61 X 51490011-51496592 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.3;testis: 36.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 15.3;Late spermatids: 17.1;Peritubular cells: 20.7;Spermatocytes: 14.6;Spermatogonia: 20.3" "Group enriched" "Detected in many" 4 "glioma: 12.1;prostate cancer: 10.6;testis cancer: 17.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HAP1: 69.3;NTERA-2: 42.9" "Low region specificity" "Detected in many" "HPA047027, HPA057684" Approved Approved Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 36: Stromal cells - Cell proliferation" Cytosol "HPA047027: AB_2679907, HPA057684: AB_2683501" "unprognostic (2.01e-1)" "unprognostic (2.57e-1)" "unprognostic (8.21e-2)" "unprognostic (1.93e-3)" "unprognostic (6.61e-2)" "unprognostic (1.13e-3)" "unprognostic (5.52e-3)" "unprognostic (1.25e-1)" "unprognostic (2.25e-2)" "unprognostic (2.18e-1)" "unprognostic (8.41e-2)" "unprognostic (1.33e-1)" "unprognostic (7.80e-12)" "unprognostic (4.34e-4)" "unprognostic (1.17e-2)" "unprognostic (2.78e-1)" "unprognostic (3.94e-4)" 1.0 4.6 11.9 0.9 13.7 1.4 2.1 4.5 14.7 4.0 2.1 2.9 1.1 5.1 3.5 1.3 2.0 1.6 0.5 13.4 20.0 0.5 0.1 0.5 0.6 5.6 7.2 8.9 4.9 0.2 4.3 0.0 8.4 9.1 0.8 2.2 0.7 10.4 0.1 1.2 1.0 4.4 5.6 0.3 1.1 36.2 23.3 2.6 0.6 0.5 0.6 1.9 2.4 7.7 0.0 1.0 20.6 0.0 17.5 22.0 0.1 9.8 2.7 0.5 0.5 0.0 0.0 0.0 0.5 11.9 11.4 1.5 69.3 23.9 0.3 0.0 4.7 0.0 0.0 0.0 8.2 0.0 4.6 13.5 9.3 6.2 22.4 3.9 16.4 21.6 0.1 0.0 19.6 0.5 27.6 0.1 42.9 0.0 17.5 0.0 14.4 0.0 4.3 0.0 0.0 13.4 4.2 0.0 4.0 10.2 0.0 0.1 9.6 4.8 22.4 1.4 0.0 9.0 4.5 15.2 3.1 0.0 1.9 0.0 0.0 0.0 1.2 0.0 0.5 0.1 0.3 0.6 0.1 0.1 0.0 0.9 0.0 0.7 0.1 0.0 0.0 0.3 11.9 13.7 4.5 14.7 13.4 20.0 5.6 7.2 8.4 5.6 23.3 7.7 0.4 0.0 0.0 0.3 0.3 15.3 6.4 12.8 12.0 1.6 0.5 3.9 0.6 0.0 1.6 0.0 0.0 0.3 3.5 0.0 0.0 0.2 11.3 0.5 9.0 0.9 0.0 1.3 6.3 1.5 1.0 7.7 0.0 0.3 0.0 3.4 0.4 0.0 0.1 0.0 3.8 0.0 0.0 0.3 3.8 17.1 8.7 0.6 5.4 2.8 0.0 1.4 3.1 4.0 0.6 1.4 0.0 20.7 0.3 10.4 0.0 0.2 0.2 0.2 0.0 3.0 5.3 14.6 20.3 1.6 9.1 0.3 0.8 7.5 0.0 1.3 OLFM2 "NOE2, OlfC" ENSG00000105088 "Olfactomedin 2" O95897 19 9853718-9936552 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 202.6;skin 1: 94.8" "Cell type enhanced" "Detected in many" "Astrocytes: 108.4;Basal keratinocytes: 125.0;Muller glia cells: 91.1;Oligodendrocyte precursor cells: 124.7;Suprabasal keratinocytes: 118.1" "Cancer enhanced" "Detected in all" "glioma: 96.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 49.7" "Group enriched" "Detected in many" 26 "granulocytes: 49.7;T-cells: 17.0" "Cell line enhanced" "Detected in many" "AN3-CA: 25.6;ASC diff: 23.4;BJ hTERT+: 18.5;SH-SY5Y: 24.3;U-2 OS: 28.7;WM-115: 25.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049961, HPA057771" Uncertain Approved Nucleoplasm "Secreted in other tissues" NA NA 2700000 "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm "HPA049961: AB_2680972, HPA057771: AB_2683524" "unprognostic (1.42e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.99e-2)" "unprognostic (5.91e-2)" "unprognostic (3.39e-2)" "unprognostic (8.78e-2)" "unprognostic (4.47e-2)" "unprognostic (8.04e-2)" "unprognostic (4.03e-2)" "unprognostic (1.41e-3)" "unprognostic (2.77e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.23e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-2)" "unprognostic (1.23e-1)" 36.8 30.7 130.8 3.4 134.5 0.2 25.0 118.5 202.6 17.2 80.7 4.8 2.1 16.7 4.5 5.6 11.1 6.7 10.1 134.0 127.3 9.2 41.9 10.1 7.9 152.5 168.8 9.7 11.2 9.6 19.1 7.1 162.0 10.1 1.1 24.6 10.0 13.4 1.8 94.8 3.8 6.7 130.0 2.5 2.2 10.7 123.2 16.5 13.2 1.0 4.8 3.0 14.1 120.7 0.0 3.7 3.0 25.6 23.4 14.3 1.7 5.6 18.5 1.2 1.5 0.3 2.4 0.1 2.3 4.2 2.1 1.5 9.8 1.7 0.1 0.1 2.1 0.0 0.2 0.3 0.1 0.0 4.3 7.5 1.5 0.1 0.2 0.7 0.1 4.8 0.3 0.3 0.0 8.2 0.3 0.2 15.8 2.5 0.0 0.1 0.0 0.0 0.0 0.9 0.1 24.3 0.9 0.1 5.2 9.7 0.9 0.0 0.3 10.5 28.7 0.1 0.1 0.0 0.0 0.0 0.3 0.0 25.6 21.2 0.0 49.7 6.2 0.0 6.6 0.0 7.0 5.5 0.0 0.0 13.5 8.9 0.5 1.2 0.0 0.1 17.0 2.9 130.8 134.5 118.5 202.6 134.0 127.3 152.5 168.8 162.0 130.0 123.2 120.7 12.9 0.0 0.0 108.4 0.3 125.0 4.7 5.9 8.6 4.9 6.9 13.8 0.8 7.2 0.4 7.3 0.0 0.1 1.0 0.1 1.9 0.9 8.6 0.9 2.2 4.3 1.2 0.4 27.3 2.4 0.0 17.2 0.0 1.0 4.5 6.5 1.4 24.7 0.3 1.7 51.0 0.2 2.0 0.3 32.6 52.8 13.7 0.6 17.8 15.0 0.4 91.1 7.2 124.7 3.5 4.1 0.0 9.8 0.5 7.9 0.0 0.2 0.2 3.7 0.0 7.4 24.3 3.0 10.4 1.4 118.1 0.1 7.7 0.6 0.1 2.9 OLFML1 UNQ564 ENSG00000183801 "Olfactomedin like 1" Q6UWY5 11 7485388-7511377 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 52.3;Leydig cells: 39.7;Peritubular cells: 39.5;Sertoli cells: 26.3;Smooth muscle cells: 16.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BEWO: 31.2;U-2197: 20.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058824 Approved "Secreted - unknown location" NA NA 260000 "Cluster 14: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA058824: " "unprognostic (3.05e-1)" "unprognostic (5.35e-2)" "unprognostic (1.52e-1)" "unprognostic (3.80e-2)" "unprognostic (5.32e-1)" "unprognostic (1.82e-3)" "unprognostic (1.36e-1)" "unprognostic (1.16e-1)" "unprognostic (7.33e-2)" "unprognostic (1.37e-2)" "unprognostic (2.30e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.28e-8)" "unprognostic (3.13e-3)" "unprognostic (2.00e-2)" "unprognostic (3.34e-2)" "unprognostic (8.72e-3)" 21.6 6.2 1.4 5.2 1.8 0.3 12.5 2.2 1.9 27.2 7.5 8.4 5.0 19.0 21.3 8.2 17.5 23.8 14.8 1.8 1.9 6.4 10.8 18.9 9.3 2.0 1.5 48.6 2.8 2.3 3.1 7.3 1.7 14.1 10.2 0.2 5.6 18.3 5.2 8.3 7.2 18.0 1.2 14.7 5.4 4.1 2.1 3.2 8.2 12.1 5.6 14.9 17.7 2.0 0.0 0.0 0.4 0.0 1.9 1.9 31.2 0.3 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.2 0.1 0.1 0.1 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 6.4 0.0 0.0 0.1 0.2 0.1 20.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.6 0.1 0.1 0.2 0.0 0.8 0.1 0.0 0.0 1.4 1.8 2.2 1.9 1.8 1.9 2.0 1.5 1.7 1.2 2.1 2.0 6.1 0.0 0.0 1.0 0.4 5.2 0.0 0.0 1.2 0.1 0.2 0.3 1.0 0.0 0.6 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.3 13.3 2.9 0.0 0.0 0.1 0.0 2.0 52.3 0.0 0.4 0.0 0.0 5.0 0.9 0.6 0.0 0.1 0.0 0.0 0.0 6.1 0.7 39.7 0.4 7.2 2.8 0.0 0.0 0.0 0.5 1.4 0.1 0.0 39.5 0.2 0.1 0.0 0.3 0.0 0.0 26.3 9.4 16.3 0.3 0.1 0.2 3.7 0.3 0.7 5.0 0.0 0.1 PCDH18 "KIAA1562, PCDH68L" ENSG00000189184 "Protocadherin 18" Q9HCL0 4 137518918-137532494 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 44.2" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 72.3;Fibroblasts: 56.3;Leydig cells: 37.9;Peritubular cells: 58.6;Sertoli cells: 19.7;Smooth muscle cells: 25.5;Theca cells: 18.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 148.2;ASC diff: 175.0;ASC TERT1: 190.8;BJ hTERT+: 86.8;fHDF/TERT166: 143.3;HHSteC: 129.4;HSkMC: 195.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017976 Approved Approved "Golgi apparatus,Cytosol" No NA 5900000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" Cytosol "Golgi apparatus" "HPA017976: AB_1855045" "unprognostic (2.77e-1)" "unprognostic (1.86e-2)" "unprognostic (3.73e-3)" "unprognostic (9.19e-2)" "unprognostic (1.59e-1)" "unprognostic (3.39e-2)" "unprognostic (2.36e-1)" "unprognostic (4.30e-2)" "unprognostic (1.97e-3)" "unprognostic (2.20e-2)" "unprognostic (8.76e-2)" "unprognostic (9.45e-2)" "prognostic unfavorable (3.21e-4)" "unprognostic (1.79e-2)" "unprognostic (6.27e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (4.71e-4)" 22.2 5.2 2.6 7.9 3.0 0.1 13.5 2.8 3.2 25.3 2.6 12.2 9.3 30.4 11.2 6.4 11.7 22.5 6.5 2.5 4.8 7.1 2.1 7.2 1.7 4.1 5.8 21.0 1.5 2.0 2.4 44.2 3.8 17.5 13.8 2.1 6.5 13.5 2.6 4.1 8.7 18.4 3.2 6.4 6.7 4.5 3.9 3.6 5.1 23.2 1.4 10.8 8.4 3.0 0.0 0.3 148.2 0.0 175.0 190.8 0.1 27.4 86.8 5.0 7.7 0.3 0.0 0.0 0.1 143.3 0.4 0.4 34.2 0.7 2.6 0.2 1.0 0.0 0.0 0.0 129.4 0.0 0.1 195.9 0.3 9.4 3.8 4.7 1.0 0.7 0.0 0.6 2.8 0.0 3.9 0.1 0.3 0.0 2.7 11.7 4.1 0.0 0.0 0.1 0.0 9.6 0.0 0.0 0.2 38.3 0.9 0.0 0.0 69.3 4.2 13.9 0.5 0.2 0.0 0.0 3.9 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.0 2.8 3.2 2.5 4.8 4.1 5.8 3.8 3.2 3.9 3.0 3.4 0.0 0.5 1.3 0.0 4.1 0.4 0.1 2.2 2.5 1.1 1.7 1.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.6 1.9 72.3 3.0 0.0 0.0 0.2 0.0 0.3 56.3 0.0 1.7 0.0 6.4 2.5 0.0 3.1 0.0 9.0 0.0 0.0 0.0 7.8 1.3 37.9 0.9 1.8 10.3 0.0 6.8 0.0 0.0 0.6 0.0 0.0 58.6 0.1 0.0 0.0 0.1 0.0 0.2 19.7 6.6 25.5 0.6 0.1 1.2 2.6 0.8 0.7 18.5 0.0 0.1 PCDHB10 ENSG00000120324 "Protocadherin beta 10" Q9UN67 5 141192353-141195647 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.9;Endometrial stromal cells: 3.4;Endothelial cells: 3.2;Enteroendocrine cells: 4.2;granulocytes: 4.5;Peritubular cells: 4.1" "Cancer enhanced" "Detected in many" "glioma: 4.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 6.6;ASC TERT1: 6.4;EFO-21: 14.1;U-2197: 7.0" HPA013445 Uncertain NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" "HPA013445: AB_1855054" "unprognostic (1.08e-1)" "unprognostic (8.41e-2)" "unprognostic (4.03e-2)" "unprognostic (1.51e-2)" "unprognostic (1.94e-1)" "unprognostic (7.30e-2)" "unprognostic (1.81e-2)" "unprognostic (2.74e-1)" "unprognostic (2.61e-2)" "unprognostic (3.96e-3)" "unprognostic (2.16e-1)" "unprognostic (3.25e-1)" "unprognostic (5.40e-3)" "unprognostic (4.56e-2)" "unprognostic (3.11e-2)" "unprognostic (1.76e-1)" "unprognostic (1.83e-3)" 1.4 1.8 2.1 0.5 1.9 0.0 1.7 1.1 2.7 2.3 0.0 2.6 0.5 3.4 1.6 0.8 1.8 1.5 1.6 2.4 0.9 0.7 0.2 1.4 0.3 1.6 2.5 2.5 0.7 1.3 3.6 0.7 1.5 1.6 0.7 1.5 1.1 1.5 0.5 0.9 0.8 3.1 1.2 0.6 0.9 0.7 2.6 0.2 0.9 0.7 0.1 1.6 1.4 2.1 0.0 0.0 3.9 3.7 6.6 6.4 0.2 0.4 3.6 0.1 0.3 0.0 0.3 0.1 14.1 1.0 2.9 0.1 0.7 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.7 2.5 0.0 0.0 3.5 0.3 0.0 0.0 4.3 1.3 0.1 0.1 0.1 0.1 0.0 0.2 0.8 2.4 0.0 0.5 0.0 2.6 5.4 4.4 0.1 0.6 0.4 2.9 0.2 1.4 3.6 2.0 7.0 1.0 0.0 0.0 0.0 4.4 0.2 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.9 1.1 2.7 2.4 0.9 1.6 2.5 1.5 1.2 2.6 2.1 2.6 0.0 0.5 0.0 0.0 0.0 0.1 1.5 0.0 8.9 0.5 0.9 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.1 3.4 3.2 4.2 0.0 0.0 0.9 0.0 2.1 0.0 0.2 4.5 0.2 1.4 0.0 0.1 0.0 0.0 0.3 2.0 0.0 0.4 0.6 1.2 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.0 4.1 0.0 0.0 0.0 0.2 0.1 0.2 0.0 2.9 1.6 1.9 0.6 0.2 0.4 0.1 0.1 0.3 0.0 0.3 PCDHB7 PCDH-BETA7 ENSG00000113212 "Protocadherin beta 7" Q9Y5E2 5 141172644-141176383 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Early spermatids: 38.4;Late spermatids: 27.3;Spermatocytes: 24.5" "Cancer enriched" "Detected in many" 5 "glioma: 5.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 3.9;EFO-21: 4.8;U-138 MG: 3.2;U-2197: 9.6;U-87 MG: 3.3;WM-115: 3.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059271 Approved NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA059271: AB_2683962" "unprognostic (2.13e-1)" "unprognostic (4.71e-2)" "unprognostic (2.36e-2)" "unprognostic (1.97e-1)" "unprognostic (5.95e-2)" "unprognostic (3.69e-4)" "unprognostic (1.04e-2)" "unprognostic (2.78e-2)" "unprognostic (8.42e-2)" "unprognostic (1.32e-1)" "unprognostic (1.57e-3)" "unprognostic (2.29e-1)" "unprognostic (1.83e-3)" "unprognostic (2.35e-2)" "unprognostic (2.34e-1)" "unprognostic (1.48e-1)" "unprognostic (5.78e-4)" 1.7 0.7 0.5 0.9 0.6 0.0 2.0 0.6 1.6 2.9 0.0 1.5 0.4 4.5 1.6 0.3 2.6 1.5 1.6 1.0 0.7 1.0 0.3 2.0 0.2 1.7 1.2 2.3 0.4 0.3 2.4 0.2 1.2 1.1 0.4 1.4 0.6 1.0 0.4 0.7 0.8 3.1 0.9 0.7 0.7 2.0 0.6 0.2 1.0 0.6 0.2 1.3 1.5 1.0 0.0 0.0 0.4 0.4 3.9 1.9 0.0 0.2 0.5 0.1 0.1 0.0 0.1 0.0 4.8 0.5 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.0 1.4 1.0 0.3 0.0 0.8 0.0 2.1 0.0 0.7 3.2 0.6 9.6 0.1 0.0 0.0 0.0 3.3 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.6 1.6 1.0 0.7 1.7 1.2 1.2 0.9 0.6 1.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 4.9 0.2 0.5 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 38.4 0.3 2.4 1.1 0.0 0.0 0.0 0.4 0.0 2.1 0.0 0.1 0.0 0.0 1.8 0.0 0.1 1.7 0.0 0.0 6.1 0.0 0.0 27.3 0.9 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.3 6.6 3.4 2.1 24.5 0.7 0.0 0.9 0.1 0.0 0.3 0.0 0.0 PCNX2 "FLJ11383, KIAA0435, PCNXL2" ENSG00000135749 "Pecanex 2" A6NKB5 1 232983435-233295725 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Collecting duct cells: 12.9;Endometrial ciliated cells: 9.3;Endometrial stromal cells: 8.8;Glandular and luminal cells: 11.1;Granulosa cells: 8.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013815, HPA014427" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum" "HPA013815: AB_2236561, HPA014427: AB_1855081" "unprognostic (3.15e-1)" "unprognostic (5.61e-3)" "unprognostic (1.92e-2)" "unprognostic (1.44e-2)" "unprognostic (2.54e-1)" "unprognostic (1.31e-1)" "unprognostic (1.58e-2)" "unprognostic (1.71e-1)" "unprognostic (4.25e-2)" "unprognostic (3.79e-1)" "unprognostic (2.40e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (2.27e-5)" "unprognostic (1.12e-1)" "unprognostic (2.92e-2)" "unprognostic (1.49e-2)" "unprognostic (1.29e-1)" 4.2 2.1 8.4 2.5 8.9 2.2 3.8 6.2 18.3 4.0 0.0 2.3 1.5 3.1 6.6 3.6 4.2 3.9 1.7 15.7 1.8 4.8 0.6 2.5 5.0 1.9 4.7 7.1 4.5 3.6 14.8 1.0 2.5 4.7 2.1 11.5 4.7 3.6 3.1 4.7 5.2 2.4 0.3 3.9 3.4 2.8 8.2 3.3 5.6 0.6 3.7 4.7 5.1 6.8 5.1 12.0 6.4 0.1 10.3 11.1 1.9 3.0 8.6 3.1 5.3 3.9 6.0 10.5 6.8 8.1 11.1 8.2 2.9 8.5 7.1 8.9 8.7 0.1 6.6 0.0 4.6 3.5 2.0 8.5 7.4 6.0 23.6 10.3 5.8 7.7 0.0 5.5 3.0 3.0 9.8 0.2 20.7 4.2 7.2 0.1 1.7 1.5 5.5 7.7 11.0 9.2 4.4 1.8 1.8 3.6 4.3 0.9 2.2 8.4 5.4 9.6 9.9 6.5 7.3 0.1 7.7 3.8 9.9 0.3 0.2 0.1 0.7 0.1 0.5 0.3 0.6 0.7 0.5 0.3 0.2 0.5 0.1 0.2 0.1 0.1 0.7 0.3 8.4 8.9 6.2 18.3 15.7 1.8 1.9 4.7 2.5 0.3 8.2 6.8 7.0 9.6 5.9 0.0 1.6 0.0 0.0 0.0 0.0 0.0 6.9 7.4 0.0 0.0 6.8 12.9 0.0 0.4 5.8 0.0 7.9 6.4 0.0 9.3 8.8 1.1 0.0 0.0 0.0 3.3 1.6 3.6 0.0 11.1 1.3 8.9 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 5.6 0.0 0.0 1.7 0.0 0.0 1.7 4.4 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.3 6.5 4.3 0.0 0.0 PDE5A ENSG00000138735 "Phosphodiesterase 5A" O76074 4 119494397-119628804 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 66.1;Inhibitory neurons: 58.3;Oligodendrocyte precursor cells: 56.8;Peritubular cells: 104.9;Smooth muscle cells: 80.9" "Group enriched" "Detected in all" 4 "prostate cancer: 7.0;thyroid cancer: 27.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 47.5;HHSteC: 65.9;hTERT-RPE1: 24.6" "Region enhanced" "Detected in all" "cerebellum: 18.2" "Low region specificity" "Detected in all" "HPA004729, HPA012873" Approved Approved Cytosol NA NA 850000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA004729: AB_1079588, HPA012873: AB_1855124" "unprognostic (6.95e-2)" "prognostic favorable (5.20e-4)" "unprognostic (1.28e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (7.36e-2)" "unprognostic (2.58e-2)" "unprognostic (2.29e-2)" "unprognostic (6.97e-2)" "unprognostic (2.05e-2)" "unprognostic (2.54e-1)" "unprognostic (2.16e-2)" "unprognostic (1.52e-2)" "unprognostic (8.98e-2)" "unprognostic (8.71e-3)" "prognostic unfavorable (1.17e-4)" 15.4 11.3 0.9 10.9 3.5 2.1 9.6 4.9 3.7 32.7 12.6 37.0 15.5 14.4 41.5 41.3 22.9 10.4 12.8 1.4 3.6 5.9 1.5 22.1 6.4 4.9 8.2 5.4 12.4 8.3 3.5 13.2 5.2 59.8 25.9 9.6 9.8 49.8 6.9 5.0 18.9 11.4 0.0 5.8 9.6 9.4 3.4 3.7 16.8 5.6 3.5 14.6 15.8 1.9 16.7 0.8 11.0 1.2 3.7 5.5 1.9 10.7 47.5 0.5 1.0 1.0 1.3 1.6 0.5 13.4 3.0 5.8 3.5 1.7 1.3 0.4 7.4 18.5 2.6 0.9 65.9 3.9 1.7 6.1 3.3 1.1 0.1 24.6 1.4 3.7 2.0 2.9 1.6 0.9 5.0 0.6 2.3 1.8 2.8 0.7 5.9 4.3 4.1 4.9 4.3 8.8 13.0 15.3 1.3 8.1 2.7 2.1 2.5 6.2 5.2 3.4 1.5 4.1 2.0 1.5 5.9 1.0 0.9 0.0 0.0 0.0 0.1 0.0 0.5 0.4 0.3 0.1 0.0 0.3 0.1 0.2 0.4 0.2 0.1 0.1 0.1 1.2 0.9 3.5 4.9 3.7 1.4 3.6 4.9 8.2 5.2 0.0 3.4 1.9 7.8 6.4 3.9 19.9 1.3 3.4 2.8 1.1 5.7 8.1 11.0 8.4 5.5 14.3 3.7 1.8 14.6 0.4 0.9 15.5 0.0 15.8 30.6 5.0 12.6 7.8 2.4 0.0 66.1 2.9 0.3 28.1 1.1 3.9 1.3 1.6 0.7 0.9 0.3 5.0 58.3 9.5 2.0 0.0 3.5 11.5 20.8 11.3 5.4 40.3 1.3 28.5 2.1 56.8 41.1 3.9 10.3 104.9 1.4 3.6 7.9 0.5 0.8 5.8 19.7 5.5 80.9 5.4 6.3 3.5 2.4 0.3 1.7 7.0 11.1 2.6 PDGFRA "CD140a, GAS9, PDGFR2" ENSG00000134853 "Platelet derived growth factor receptor alpha" P16234 4 54229280-54298245 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 190.2" "Group enriched" "Detected in many" 8 "Endometrial stromal cells: 423.9;Fibroblasts: 256.4;Leydig cells: 449.8;Oligodendrocyte precursor cells: 499.6;Peritubular cells: 408.9" "Cancer enhanced" "Detected in all" "glioma: 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 468.1;ASC TERT1: 216.1;BJ hTERT+: 279.4;fHDF/TERT166: 195.9;HHSteC: 156.3;HSkMC: 392.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004947, CAB018143" Supported Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 300000 "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Plasma membrane, Cell Junctions" "CAB018143: AB_2162351, HPA004947: AB_2732399" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "unprognostic (4.59e-3)" "unprognostic (1.60e-1)" "unprognostic (8.92e-2)" "prognostic favorable (9.33e-4)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.18e-2)" "unprognostic (2.18e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (9.79e-6)" "unprognostic (9.58e-3)" "unprognostic (9.87e-2)" "unprognostic (2.16e-2)" "unprognostic (1.72e-3)" 46.0 28.9 13.9 40.4 13.7 1.6 40.1 8.1 12.8 50.8 18.1 37.7 22.4 44.3 21.8 22.5 50.9 38.5 32.1 11.9 11.0 26.5 16.0 37.9 8.5 16.7 11.9 190.2 13.4 3.0 3.7 62.7 15.1 15.0 35.2 5.3 16.6 18.9 9.6 14.8 31.3 48.1 12.1 46.2 29.4 13.6 8.9 7.6 16.5 41.9 7.2 63.9 38.0 20.0 0.1 0.0 1.0 0.8 468.1 216.1 0.5 25.4 279.4 0.1 0.7 67.6 0.5 0.5 0.5 195.9 0.8 0.6 19.6 0.2 0.1 2.6 1.0 0.7 0.7 1.2 156.3 0.3 0.4 392.0 0.0 31.4 0.0 5.4 0.0 0.7 0.6 0.9 1.1 0.1 0.4 1.2 3.5 0.3 1.1 0.5 0.1 0.1 0.0 0.4 0.6 37.9 0.0 0.5 0.2 2.0 0.7 0.1 0.8 84.9 3.2 93.9 0.2 0.4 0.1 0.8 2.6 0.1 2.2 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 13.9 13.7 8.1 12.8 11.9 11.0 16.7 11.9 15.1 12.1 8.9 20.0 11.1 0.0 0.5 0.3 0.6 17.1 0.6 2.4 1.2 5.5 4.3 3.2 4.8 0.0 0.8 0.0 0.0 1.4 0.9 0.1 1.9 4.2 2.2 11.7 423.9 5.7 0.0 0.0 1.1 6.7 2.0 256.4 5.1 9.0 0.0 2.6 26.0 1.0 3.1 0.0 19.5 0.2 10.2 0.6 27.3 17.2 449.8 5.4 23.2 39.4 4.7 17.5 0.0 499.6 0.4 20.0 0.0 408.9 0.2 0.9 0.0 0.1 0.5 0.6 0.0 25.7 13.9 1.0 3.4 8.1 15.8 1.4 2.5 49.6 0.0 1.0 PHGDH "PDG, PGDH, SERA" ENSG00000092621 "Phosphoglycerate dehydrogenase" O43175 1 119648411-119744218 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Serine biosynthesis" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 135.0;Exocrine glandular cells: 136.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 25.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-MEL-30: 975.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003681, HPA021241, HPA024031, CAB068216" Enhanced Enhanced "Nucleoplasm,Plasma membrane,Cytosol" No No 1100000 "Cluster 32: T-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" Nucleoplasm "CAB003681: AB_425928, CAB068216: AB_2665666, HPA021241: AB_1855299, HPA024031: AB_1855300" "unprognostic (2.30e-1)" "unprognostic (2.16e-1)" "unprognostic (1.80e-2)" "prognostic unfavorable (1.48e-4)" "prognostic favorable (1.62e-4)" "unprognostic (9.80e-2)" "unprognostic (1.56e-2)" "unprognostic (1.40e-1)" "unprognostic (5.24e-2)" "unprognostic (4.45e-3)" "unprognostic (8.80e-3)" "unprognostic (5.00e-2)" "unprognostic (2.37e-2)" "unprognostic (1.32e-1)" "unprognostic (1.74e-1)" "unprognostic (1.95e-1)" "unprognostic (1.78e-3)" 51.4 3.0 113.6 9.4 125.3 11.4 30.1 130.7 125.9 46.1 89.1 27.2 7.6 25.4 79.6 56.6 49.3 7.6 22.4 108.8 128.8 40.9 126.0 18.0 14.9 121.8 113.9 46.1 171.1 103.9 23.7 13.2 122.4 52.6 7.0 7.5 156.2 33.5 2.6 92.5 13.3 15.0 117.0 6.5 41.7 40.3 115.8 34.0 29.5 4.3 13.3 35.8 62.9 153.6 156.8 35.2 148.0 444.6 64.9 82.8 286.1 101.0 209.3 132.9 257.6 195.7 28.6 0.1 58.1 270.5 16.6 205.6 216.8 224.6 83.9 1.1 162.1 29.1 151.3 153.3 135.7 214.3 1.7 147.6 338.6 146.8 142.2 83.0 100.1 519.7 71.4 443.9 66.8 380.9 222.8 90.1 440.0 93.3 274.6 228.0 181.1 24.8 9.6 120.4 160.8 146.0 65.9 63.9 975.9 103.9 164.8 505.7 0.9 38.3 172.1 207.3 134.8 294.0 79.9 246.1 456.9 328.2 302.7 5.3 1.1 0.2 4.7 0.3 0.2 11.1 2.4 8.2 5.3 4.0 13.0 25.2 2.2 1.8 0.3 2.6 4.5 6.3 113.6 125.3 130.7 125.9 108.8 128.8 121.8 113.9 122.4 117.0 115.8 153.6 5.3 3.2 12.6 31.6 10.0 51.9 118.1 24.2 42.7 0.7 29.7 38.0 2.1 128.7 12.5 20.2 2.1 49.9 2.2 1.6 135.0 60.2 51.2 15.6 3.8 6.9 1.8 5.5 0.3 136.1 54.0 58.7 8.6 12.2 5.7 30.9 3.6 96.1 9.2 0.0 0.6 3.6 18.3 2.2 4.3 116.9 67.7 6.5 56.9 2.8 11.0 82.4 0.0 14.1 32.3 35.6 2.0 127.9 27.4 62.1 0.2 118.4 24.7 3.4 13.1 11.2 48.8 20.0 19.4 57.5 77.1 25.3 5.9 71.4 3.2 56.8 PID1 "FLJ20701, NYGGF4" ENSG00000153823 "Phosphotyrosine interaction domain containing 1" Q7Z2X4 2 228850526-229271287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 135.0;Inhibitory neurons: 142.2;Langerhans cells: 210.4;Microglial cells: 179.9;Oligodendrocyte precursor cells: 543.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 71.1;intermediate monocyte: 79.4;myeloid DC: 83.6" "Group enriched" "Detected in many" 53 "dendritic cells: 83.6;monocytes: 79.4" "Cell line enhanced" "Detected in many" "ASC diff: 54.5;hTEC/SVTERT24-B: 86.1;LHCN-M2: 57.3;REH: 62.3;RH-30: 90.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036103 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA036103: AB_10602144" "unprognostic (8.46e-2)" "unprognostic (2.96e-1)" "unprognostic (3.55e-2)" "unprognostic (5.52e-2)" "unprognostic (9.40e-3)" "unprognostic (2.66e-2)" "unprognostic (1.21e-2)" "unprognostic (6.36e-2)" "unprognostic (1.54e-2)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.46e-1)" "unprognostic (4.91e-3)" "unprognostic (9.98e-3)" "unprognostic (1.11e-1)" "unprognostic (5.34e-2)" "unprognostic (9.61e-6)" 31.2 29.5 18.8 13.9 20.8 2.9 25.8 9.0 21.2 30.2 9.0 37.6 5.5 22.9 8.9 12.0 33.9 12.7 17.0 20.6 15.5 5.6 62.2 24.4 4.4 14.8 30.5 31.0 13.8 1.5 8.8 26.1 13.6 19.2 21.5 3.8 10.2 14.8 13.1 20.0 25.1 16.7 11.8 20.3 25.5 5.5 21.4 3.4 16.6 20.8 3.6 30.9 27.0 13.8 0.0 1.9 0.0 0.0 54.5 10.5 0.1 9.2 34.7 5.8 7.1 0.7 0.0 0.0 0.2 13.0 18.0 1.7 0.0 1.7 7.8 0.0 0.0 0.0 4.0 0.1 22.3 0.0 0.1 19.8 15.5 86.1 14.0 16.1 0.0 0.0 0.0 0.1 57.3 0.1 0.1 0.0 0.9 7.6 5.2 62.3 90.7 0.1 1.1 0.0 1.8 2.3 19.4 1.8 0.1 0.7 0.2 0.0 0.0 22.3 8.3 21.1 8.8 0.1 0.0 0.0 29.3 0.1 3.7 0.0 71.1 0.0 0.0 79.4 0.4 0.2 0.0 0.2 83.6 0.0 0.0 0.0 1.5 0.0 16.7 0.4 0.3 28.4 18.8 20.8 9.0 21.2 20.6 15.5 14.8 30.5 13.6 11.8 21.4 13.8 4.0 6.4 70.9 53.8 1.6 15.6 6.1 13.5 6.8 5.7 0.9 1.7 2.6 8.6 11.1 0.0 0.0 1.9 0.2 75.7 0.0 2.5 0.1 1.4 37.8 4.1 4.9 0.4 121.0 4.0 31.5 107.3 1.1 4.4 6.3 7.8 4.2 135.0 3.3 0.0 142.2 11.9 4.1 42.5 210.4 1.9 88.0 50.1 21.4 179.9 35.2 14.0 1.0 543.4 3.5 1.6 24.2 75.2 0.5 21.9 39.5 0.3 2.5 1.3 0.0 4.8 8.7 0.4 2.1 1.4 14.5 4.8 2.4 41.0 36.0 1.4 PIF1 "C15orf20, FLJ22692" ENSG00000140451 "PIF1 5'-to-3' DNA helicase" Q9H611 15 64815632-64825668 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4.8" "Cell type enhanced" "Detected in many" "Early spermatids: 21.3;Erythroid cells: 17.7;Granulosa cells: 15.1;NK-cells: 15.5;Theca cells: 18.3" "Cancer enhanced" "Detected in many" "testis cancer: 10.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB018701 Supported Supported Nucleoplasm NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB018701: AB_2164654" "unprognostic (1.99e-1)" "unprognostic (6.11e-2)" "unprognostic (1.34e-1)" "unprognostic (3.12e-2)" "unprognostic (1.62e-1)" "unprognostic (8.33e-3)" "unprognostic (8.66e-4)" "unprognostic (1.47e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (6.68e-2)" "unprognostic (2.38e-2)" "unprognostic (3.27e-2)" "unprognostic (0.00e+0)" "unprognostic (2.96e-3)" "unprognostic (1.78e-1)" "unprognostic (9.61e-2)" "unprognostic (5.95e-2)" 0.7 1.0 0.8 2.6 0.8 3.8 0.4 0.7 1.3 0.9 0.7 2.4 1.9 0.8 0.1 3.1 0.7 0.8 0.9 0.7 1.2 0.6 0.6 1.0 4.6 1.4 1.0 0.4 0.2 0.2 0.5 0.9 1.1 1.7 1.0 0.1 0.6 0.7 0.3 1.0 2.6 1.2 0.9 4.8 1.8 2.5 1.2 3.6 0.5 0.1 3.3 1.5 1.4 0.8 7.7 8.7 21.1 8.6 3.7 4.3 7.8 7.4 3.9 7.3 5.6 14.0 12.6 9.3 3.0 3.6 6.8 20.9 21.8 6.2 2.7 14.8 8.0 10.8 28.5 10.2 1.9 4.3 8.4 2.5 0.0 3.2 2.6 1.8 7.5 13.6 7.2 18.0 7.0 6.7 4.7 17.9 17.2 9.7 6.0 9.7 7.0 13.0 4.1 4.3 8.7 5.6 5.7 6.3 3.3 9.2 7.0 4.7 5.2 4.4 22.6 7.0 14.0 14.3 14.3 9.0 4.2 18.8 6.4 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.1 0.8 0.8 0.7 1.3 0.7 1.2 1.4 1.0 1.1 0.9 1.2 0.8 1.2 0.0 1.1 3.6 6.5 1.9 0.8 0.6 0.0 0.5 0.6 0.6 1.9 0.0 0.1 0.0 0.0 5.1 7.5 3.2 0.0 0.0 21.3 0.4 4.4 2.3 0.0 17.7 2.6 0.0 6.5 5.6 3.6 0.7 0.0 15.1 5.3 0.5 5.8 0.0 1.0 2.4 0.0 5.1 2.0 2.3 1.5 4.5 0.0 1.9 0.1 0.8 15.5 3.5 0.1 0.2 0.1 2.2 9.7 1.1 0.2 0.1 0.1 1.2 6.6 4.2 3.5 0.8 2.0 1.6 1.0 1.1 7.5 18.3 6.2 1.3 PINLYP ENSG00000234465 "Phospholipase A2 inhibitor and LY6/PLAUR domain containing" A6NC86 19 43575801-43583964 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 23.5;Proximal tubular cells: 19.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 21.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 73.1;HMC-1: 46.6;JURKAT: 37.1;REH: 29.8;THP-1: 36.6" "Not detected" "Not detected" HPA061218 Uncertain Approved Vesicles "Secreted to blood" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 35: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA061218: AB_2684453" "unprognostic (6.72e-2)" "unprognostic (6.21e-2)" "unprognostic (4.72e-1)" "unprognostic (3.13e-2)" "unprognostic (2.46e-3)" "unprognostic (1.20e-1)" "unprognostic (1.20e-1)" "unprognostic (1.22e-2)" "unprognostic (5.07e-2)" "unprognostic (2.00e-1)" "unprognostic (2.85e-2)" "unprognostic (1.14e-1)" "unprognostic (4.36e-3)" "unprognostic (1.95e-2)" "unprognostic (1.68e-1)" "unprognostic (1.08e-1)" "unprognostic (3.60e-2)" 9.9 3.5 16.3 3.3 16.7 2.7 8.5 18.1 22.1 17.3 16.1 13.3 1.4 14.7 9.4 10.5 17.1 9.3 9.8 16.1 16.8 22.9 2.1 7.7 5.0 17.2 17.0 19.6 2.4 0.7 14.9 2.8 16.0 13.5 3.0 2.6 5.8 10.4 1.7 7.6 6.4 11.1 16.4 8.4 7.3 5.4 17.4 10.6 11.8 3.3 5.2 10.3 13.0 15.7 0.7 0.3 1.9 0.3 3.4 4.5 0.4 0.8 1.2 1.6 4.3 0.0 0.1 0.0 0.2 19.0 1.8 4.0 0.0 0.2 1.5 0.1 0.2 73.1 0.8 0.1 10.3 0.0 46.6 10.2 0.4 10.3 0.2 4.3 2.7 37.1 0.9 1.0 0.7 0.4 8.9 1.1 1.8 0.1 0.7 29.8 0.2 0.0 0.8 0.4 0.3 0.0 0.0 0.4 0.1 0.3 0.1 36.6 1.2 4.7 0.9 0.1 3.1 0.0 0.0 4.4 16.0 0.0 0.4 10.4 1.5 0.7 3.0 1.2 3.6 1.7 0.9 2.5 2.3 4.7 0.3 3.6 0.5 1.4 0.2 21.0 2.0 1.7 16.3 16.7 18.1 22.1 16.1 16.8 17.2 17.0 16.0 16.4 17.4 15.7 1.8 12.8 3.2 2.3 1.1 3.6 10.0 5.6 8.6 6.1 2.4 5.6 2.8 8.6 5.7 9.2 6.2 0.4 1.8 0.1 23.5 1.3 6.4 2.1 9.9 4.3 0.0 4.4 0.5 0.4 0.4 9.1 2.0 2.0 0.0 7.6 5.7 0.0 5.1 6.7 1.1 0.8 2.0 1.0 3.9 7.3 11.5 2.7 5.4 1.9 3.3 5.6 0.0 5.0 0.5 0.4 0.1 9.8 1.7 5.2 0.7 19.0 15.0 3.3 0.0 2.1 5.9 2.3 1.2 6.7 3.1 0.1 1.2 13.6 1.7 6.6 PIWIL4 "FLJ36156, HIWI2, Miwi2" ENSG00000134627 "Piwi like RNA-mediated gene silencing 4" Q7Z3Z4 11 94543840-94621421 "Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis, Translation regulation" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.3" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 8.7;Spermatogonia: 12.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "NB-4: 93.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036587, HPA036588, HPA057508" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Mitochondria" "HPA036587: AB_2732473, HPA036588: AB_10673502, HPA057508: AB_2683452" "unprognostic (1.43e-1)" "unprognostic (9.46e-2)" "unprognostic (2.59e-3)" "unprognostic (2.22e-3)" "unprognostic (3.16e-2)" "unprognostic (1.07e-3)" "unprognostic (1.96e-2)" "unprognostic (5.18e-2)" "unprognostic (1.41e-1)" "unprognostic (1.70e-1)" "unprognostic (6.17e-2)" "unprognostic (2.68e-1)" "unprognostic (1.21e-4)" "unprognostic (6.89e-2)" "unprognostic (1.68e-1)" "unprognostic (2.50e-1)" "unprognostic (2.80e-2)" 3.3 1.1 5.5 2.8 5.3 24.3 3.6 4.9 5.0 4.4 3.4 5.8 5.8 3.7 2.3 1.6 3.6 4.6 2.8 5.6 4.7 3.2 1.3 2.7 3.9 4.5 4.4 3.4 11.3 0.4 2.2 2.0 4.5 2.5 6.0 6.7 8.8 2.6 1.0 1.7 6.3 2.0 4.5 3.7 5.1 13.3 4.9 3.0 2.0 1.0 2.7 3.3 3.0 5.4 0.2 0.1 0.4 0.0 6.6 4.3 0.5 0.5 0.3 0.2 0.9 0.7 0.6 0.0 0.4 2.8 0.2 0.0 0.9 0.0 0.2 2.7 0.3 0.2 0.6 0.0 2.5 6.5 0.1 1.5 0.0 0.5 0.0 0.1 0.1 0.5 0.3 0.0 1.1 0.4 0.3 93.2 0.1 9.2 0.6 0.4 0.0 0.0 2.1 0.0 0.4 0.3 0.4 0.9 0.4 0.3 0.0 20.7 1.2 0.4 0.1 0.1 0.1 0.1 0.0 0.0 0.1 9.9 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 5.5 5.3 4.9 5.0 5.6 4.7 4.5 4.4 4.5 4.5 4.9 5.4 1.1 0.0 0.5 3.3 0.2 1.3 0.2 0.4 0.0 0.6 1.3 1.3 3.5 7.2 1.4 0.0 0.0 4.0 0.2 4.1 1.9 6.2 4.7 0.7 0.7 0.6 0.0 0.4 5.4 2.0 0.5 1.6 7.7 1.3 0.0 0.9 0.7 0.0 1.7 0.0 4.9 8.7 0.0 3.0 1.7 2.1 0.3 1.7 0.0 3.7 2.0 0.7 1.0 5.0 6.0 3.0 4.9 1.2 0.1 0.5 4.4 0.6 1.7 3.3 0.0 2.2 1.3 1.2 12.0 0.6 0.1 1.0 0.3 0.3 5.3 0.1 PLEKHH2 "KIAA2028, PLEKHH1L" ENSG00000152527 "Pleckstrin homology, MyTH4 and FERM domain containing H2" Q8IVE3 2 43637260-43767987 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Collecting duct cells: 66.2;Endometrial stromal cells: 150.5;Oligodendrocyte precursor cells: 191.0" "Cancer enhanced" "Detected in many" "renal cancer: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 7.4;RPTEC TERT1: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077225 Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 36: Stromal cells - Cell proliferation" "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA077225: AB_2686828" "unprognostic (1.11e-1)" "unprognostic (1.05e-1)" "unprognostic (3.49e-2)" "unprognostic (1.59e-1)" "unprognostic (2.16e-1)" "unprognostic (4.27e-3)" "unprognostic (1.77e-1)" "unprognostic (2.32e-2)" "unprognostic (2.94e-2)" "unprognostic (6.99e-2)" "unprognostic (2.81e-1)" "unprognostic (2.53e-2)" "unprognostic (1.92e-3)" "unprognostic (3.03e-2)" "unprognostic (1.29e-1)" "unprognostic (8.57e-3)" "unprognostic (1.82e-2)" 13.1 3.0 2.8 1.7 2.7 0.1 8.9 3.6 2.8 20.9 8.8 11.8 3.7 19.8 4.4 4.6 15.9 7.3 4.8 2.3 2.8 15.9 1.7 27.6 2.9 3.0 3.4 23.0 2.9 5.4 2.0 3.8 3.1 5.1 4.3 1.7 4.8 5.0 1.8 8.4 6.5 9.8 2.7 5.4 5.0 3.9 2.7 0.4 5.5 2.5 1.8 6.2 8.5 2.5 0.5 4.0 1.6 0.0 3.1 7.4 0.3 0.5 2.0 0.8 2.0 0.0 1.3 1.0 0.2 0.6 3.3 2.6 0.5 0.6 1.5 0.0 1.1 0.1 0.6 0.1 0.5 0.0 0.5 2.2 0.6 1.9 0.1 1.1 1.7 1.6 3.9 0.1 0.7 1.1 0.8 0.1 0.9 0.6 3.9 0.0 4.6 0.0 6.3 0.2 1.2 0.6 0.4 0.0 3.9 1.1 0.5 0.1 0.2 4.5 1.3 0.2 1.4 0.9 0.2 0.0 1.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.8 2.7 3.6 2.8 2.3 2.8 3.0 3.4 3.1 2.7 2.7 2.5 4.6 38.5 8.7 19.2 0.9 8.7 17.5 5.8 6.8 1.0 5.3 8.3 2.9 11.5 12.9 66.2 6.2 0.3 1.3 0.1 5.9 6.2 1.6 5.9 150.5 3.8 0.0 0.0 15.6 1.4 0.3 57.4 3.1 8.8 1.3 42.6 2.2 0.0 0.8 0.0 4.3 0.3 2.0 0.3 8.6 3.3 35.8 1.2 12.4 15.9 0.2 5.8 0.0 191.0 52.7 7.2 0.0 50.4 0.4 9.2 0.3 4.1 7.3 4.1 46.0 40.7 24.6 10.8 5.9 2.6 8.4 0.5 3.6 13.1 0.6 8.7 PLSCR4 ENSG00000114698 "Phospholipid scramblase 4" Q9NRQ2 3 146192335-146251179 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 77.3;Astrocytes: 151.1;Endothelial cells: 63.4;Hepatic stellate cells: 110.3;Oligodendrocyte precursor cells: 61.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 60.5;ASC TERT1: 48.2;hTERT-RPE1: 62.1;HUVEC TERT2: 50.8;TIME: 106.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002276 Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" "HPA002276: AB_1855479" "unprognostic (3.73e-3)" "unprognostic (4.03e-2)" "unprognostic (9.83e-2)" "prognostic unfavorable (3.90e-4)" "unprognostic (2.62e-1)" "unprognostic (6.77e-3)" "unprognostic (1.19e-1)" "unprognostic (4.36e-2)" "unprognostic (7.33e-2)" "unprognostic (2.49e-1)" "unprognostic (2.50e-1)" "unprognostic (4.17e-2)" "prognostic unfavorable (4.13e-4)" "unprognostic (1.79e-2)" "unprognostic (1.35e-1)" "unprognostic (8.13e-3)" "unprognostic (2.97e-3)" 60.2 43.8 30.2 9.4 28.2 2.3 41.9 30.9 32.5 28.9 11.6 27.4 6.8 30.1 15.7 23.2 41.2 45.6 28.0 28.7 38.5 25.3 69.0 37.4 10.5 39.3 44.0 36.4 20.5 4.3 11.2 56.4 32.6 13.8 25.2 13.7 23.6 25.8 7.4 16.1 13.6 33.7 36.9 30.1 14.4 21.6 41.8 6.6 31.2 18.8 6.7 19.8 25.5 32.2 0.0 9.9 1.7 0.0 60.5 48.2 0.3 11.5 15.7 5.0 10.9 1.0 12.6 0.0 12.3 21.0 5.0 1.4 2.4 1.1 2.8 0.1 0.1 5.0 7.9 1.3 28.1 0.1 1.3 29.6 1.6 10.4 3.0 62.1 50.8 0.0 0.2 0.9 7.4 0.3 0.0 0.1 2.1 5.1 3.4 0.0 0.8 0.0 0.1 0.0 0.6 0.0 20.1 0.1 3.9 2.5 0.7 0.6 106.4 10.4 2.6 23.6 2.1 0.3 0.0 0.0 2.6 0.1 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 30.2 28.2 30.9 32.5 28.7 38.5 39.3 44.0 32.6 36.9 41.8 32.2 77.3 3.2 10.3 151.1 1.0 10.8 5.6 0.8 12.0 0.6 10.2 8.6 4.1 25.8 6.0 3.7 0.0 0.7 0.3 27.4 0.0 8.2 1.1 3.6 11.6 63.4 10.3 15.6 1.7 11.6 0.5 57.1 2.0 1.5 1.3 7.0 110.3 44.1 0.8 0.0 0.6 11.7 0.0 7.1 11.8 3.8 42.9 1.1 3.6 40.3 0.1 51.4 0.0 61.3 0.6 4.7 13.3 32.4 2.8 2.6 6.4 28.3 6.4 1.5 0.0 18.9 23.6 1.2 0.9 4.8 8.7 0.8 1.8 20.0 8.1 2.7 PLXDC1 "TEM3, TEM7" ENSG00000161381 "Plexin domain containing 1" Q8IUK5 17 39063313-39154394 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 48.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 299.3;Fibroblasts: 63.8;Sertoli cells: 46.0;Skeletal myocytes: 96.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ hTERT+: 9.2;MOLT-4: 3.0;U-87 MG: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012805 Approved "Intracellular and membrane" NA NA 17000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 56: Bipolar cells - Visual perception" "HPA012805: AB_1857893" "unprognostic (4.28e-1)" "unprognostic (3.55e-1)" "unprognostic (2.56e-2)" "unprognostic (2.15e-1)" "unprognostic (9.50e-2)" "unprognostic (1.13e-2)" "unprognostic (2.35e-2)" "unprognostic (2.23e-2)" "unprognostic (4.07e-3)" "unprognostic (6.07e-3)" "unprognostic (4.62e-3)" "unprognostic (8.69e-2)" "prognostic unfavorable (9.15e-8)" "unprognostic (9.37e-3)" "unprognostic (1.72e-2)" "unprognostic (2.42e-1)" "unprognostic (2.33e-2)" 6.3 2.8 6.7 3.3 7.9 1.1 8.3 10.0 11.6 5.3 4.6 5.2 1.8 12.6 3.8 12.2 11.5 14.3 21.7 6.0 6.1 5.5 0.6 4.2 5.4 6.8 10.4 14.9 3.5 6.7 2.8 2.2 7.8 5.4 2.9 48.4 4.1 5.1 8.1 4.2 5.3 10.8 5.1 1.8 4.5 5.7 8.3 23.1 3.1 18.4 5.3 4.0 4.6 8.0 0.1 0.0 0.1 1.4 0.2 0.0 0.2 0.1 9.2 0.6 0.4 0.1 2.2 0.1 0.2 0.3 0.0 0.2 0.2 0.1 0.5 0.0 0.7 0.2 0.6 0.1 0.2 0.3 0.1 0.3 0.1 0.4 0.1 0.1 0.0 0.9 0.0 0.6 0.0 1.1 3.0 0.3 0.3 0.1 0.0 0.3 0.4 0.4 0.0 0.1 1.4 0.1 0.0 0.2 0.0 0.1 0.2 0.2 0.0 1.1 0.6 0.4 0.2 0.1 0.0 0.1 5.9 0.4 0.1 0.3 0.1 0.1 1.8 0.0 1.5 0.1 0.5 0.6 0.0 0.1 2.1 2.2 0.4 1.1 0.0 0.9 0.0 0.8 6.7 7.9 10.0 11.6 6.0 6.1 6.8 10.4 7.8 5.1 8.3 8.0 3.4 0.0 14.9 2.9 0.7 5.2 0.9 0.2 2.8 299.3 1.6 1.8 6.9 0.0 1.9 0.0 20.9 0.1 5.4 0.1 0.0 0.0 2.2 0.2 2.4 14.4 0.0 2.7 16.6 0.2 0.1 63.8 2.0 0.3 1.3 0.2 0.4 0.2 0.1 6.7 16.3 0.0 2.0 1.3 6.9 9.1 0.6 7.9 7.2 35.6 5.2 12.2 18.6 3.0 1.4 0.1 0.0 1.2 2.0 0.9 0.0 0.1 1.5 24.2 46.0 96.1 29.3 0.7 0.7 1.2 4.4 0.0 12.1 0.4 0.0 0.5 PNMA2 "MA2, RGAG2" ENSG00000240694 "PNMA family member 2" Q9UL42 8 26504701-26514092 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 88.4;retina: 24.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 71.2;Horizontal cells: 30.3;Inhibitory neurons: 92.0;Muller glia cells: 26.9" "Cancer enhanced" "Detected in many" "glioma: 28.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 63.0;hTERT-RPE1: 78.4;JURKAT: 43.3;SH-SY5Y: 44.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001936 Enhanced NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 65: Brain - Ion transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA001936: AB_1079647" "unprognostic (1.25e-2)" "unprognostic (1.27e-2)" "unprognostic (6.39e-2)" "unprognostic (1.43e-6)" "unprognostic (1.18e-1)" "unprognostic (1.37e-1)" "unprognostic (8.76e-2)" "prognostic favorable (1.81e-4)" "unprognostic (4.66e-2)" "unprognostic (1.34e-2)" "unprognostic (1.46e-2)" "unprognostic (1.52e-1)" "unprognostic (9.98e-2)" "prognostic unfavorable (6.23e-4)" "unprognostic (5.12e-2)" "unprognostic (4.58e-5)" "unprognostic (9.00e-3)" 2.6 10.8 52.2 1.2 55.1 0.4 1.9 1.3 73.4 3.5 0.0 1.4 0.8 0.8 1.0 0.5 2.5 3.9 4.9 55.1 88.4 3.2 0.9 6.8 0.4 29.0 25.7 0.8 3.9 2.7 15.4 0.5 28.7 0.8 0.9 24.5 0.3 0.9 0.5 0.6 1.1 1.9 16.5 0.5 2.8 1.7 67.0 0.2 2.7 0.2 0.3 2.2 0.8 29.2 0.0 11.7 63.0 0.6 12.2 2.6 0.1 3.2 17.2 7.8 2.6 0.5 8.4 0.0 2.3 1.2 19.3 0.2 39.5 0.0 6.0 0.0 7.0 0.0 8.7 0.1 0.9 0.0 0.4 4.2 0.0 33.4 0.2 78.4 37.7 43.3 0.0 0.1 4.9 0.3 19.3 0.1 34.7 0.7 0.1 0.1 12.8 0.0 18.7 4.3 30.7 44.9 0.0 0.1 2.1 4.5 0.2 1.2 18.6 0.8 12.7 16.1 2.6 5.9 4.6 0.1 36.1 0.0 1.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 52.2 55.1 1.3 73.4 55.1 88.4 29.0 25.7 28.7 16.5 67.0 29.2 0.4 3.2 13.0 20.5 0.6 0.0 0.1 0.2 0.0 6.5 0.9 1.1 0.5 0.0 3.7 0.0 2.1 0.0 0.0 0.1 0.0 0.3 5.4 1.0 4.5 1.0 10.8 0.0 71.2 0.0 0.1 3.6 0.0 1.5 1.3 0.0 0.4 0.1 0.1 30.3 92.0 0.5 0.0 1.6 0.8 1.5 11.1 0.1 1.8 12.2 0.0 26.9 0.0 19.1 11.5 2.7 0.0 12.0 0.0 0.0 0.0 5.4 2.9 6.2 0.0 0.2 4.0 0.1 0.9 0.0 0.0 0.0 0.1 0.0 0.2 0.2 PON3 ENSG00000105852 "Paraoxonase 3" Q15166 7 95359872-95396375 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 616.7" "Cell type enriched" "Detected in many" 11 "Hepatocytes: 509.6" "Group enriched" "Detected in many" 9 "liver cancer: 30.8;lung cancer: 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 28.9;CACO-2: 8.6;CAPAN-2: 6.5;Hep G2: 32.6;T-47d: 17.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA014848, CAB025250" Enhanced "Secreted to blood" NA NA 1760000000 380000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB025250: , HPA014848: AB_1855540" "unprognostic (2.67e-1)" "unprognostic (1.03e-1)" "unprognostic (6.28e-3)" "unprognostic (5.52e-3)" "unprognostic (1.36e-1)" "unprognostic (4.87e-1)" "unprognostic (1.44e-3)" "unprognostic (6.32e-2)" "unprognostic (1.11e-1)" "unprognostic (6.44e-3)" "unprognostic (9.14e-2)" "unprognostic (7.18e-3)" "unprognostic (8.30e-9)" "unprognostic (1.66e-1)" "unprognostic (1.04e-2)" "unprognostic (8.29e-2)" "unprognostic (5.12e-2)" 1.4 3.8 2.1 0.5 2.0 0.0 31.2 1.7 1.9 5.3 1.4 2.0 7.9 0.9 3.6 0.5 1.3 4.4 1.0 1.8 2.1 2.7 616.7 14.2 0.1 2.3 2.2 12.4 14.3 0.2 24.9 0.8 2.9 0.9 2.8 0.1 26.3 3.9 0.3 7.4 3.1 0.2 2.1 0.3 2.3 9.0 2.1 1.6 7.1 0.3 5.9 1.4 0.9 1.9 3.1 28.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 6.5 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 5.3 0.0 0.1 17.4 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.0 1.7 1.9 1.8 2.1 2.3 2.2 2.9 2.1 2.1 1.9 2.5 6.4 45.9 24.5 0.6 0.9 0.9 9.3 1.8 0.0 5.4 4.3 0.5 31.5 23.9 3.7 0.0 1.7 0.3 3.2 1.9 0.3 14.5 0.0 0.4 1.9 0.0 8.0 0.1 2.0 2.2 5.2 0.5 0.0 0.0 0.4 10.0 509.6 0.2 0.0 0.2 1.8 12.2 8.1 0.3 4.8 8.1 0.2 14.2 4.7 0.0 3.2 0.0 17.6 0.1 1.2 1.2 3.0 0.0 2.1 6.0 6.7 6.5 0.1 0.0 0.8 2.1 21.4 16.9 0.3 1.3 1.4 0.8 6.6 2.3 0.4 PRDM8 KMT8D ENSG00000152784 "PR/SET domain 8" Q9NQV8 4 80183879-80204329 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Transferase" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 26.1;seminal vesicle: 27.2" "Cell type enriched" "Detected in many" 9 "Bipolar cells: 271.5" "Cancer enhanced" "Detected in many" "prostate cancer: 4.6" "Region enhanced" "Detected in many" "cerebral cortex: 17.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 27.3;LHCN-M2: 41.7;NB-4: 48.2;SCLC-21H: 99.3" "Region enhanced" "Detected in many" "hippocampal formation: 28.7" "Low region specificity" "Detected in all" HPA057253 Supported "Nucleoplasm,Nuclear bodies" No NA "Cluster 24: B-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "Nuclear bodies" Nucleoplasm "HPA057253: AB_2683382" "unprognostic (2.33e-2)" "unprognostic (1.08e-1)" "unprognostic (1.23e-1)" "unprognostic (2.67e-1)" "unprognostic (1.15e-1)" "unprognostic (1.68e-1)" "unprognostic (1.65e-1)" "unprognostic (7.95e-2)" "unprognostic (1.19e-1)" "unprognostic (1.76e-1)" "unprognostic (2.34e-1)" "unprognostic (2.80e-2)" "unprognostic (1.89e-11)" "unprognostic (4.64e-2)" "unprognostic (1.69e-1)" "unprognostic (1.39e-1)" "unprognostic (2.56e-1)" 4.8 2.3 5.1 5.0 10.2 4.0 4.0 0.0 17.0 11.7 0.0 11.4 1.1 9.3 1.9 1.7 5.2 1.7 1.7 13.7 0.0 1.3 0.3 1.6 5.1 0.0 0.0 5.2 0.9 0.0 5.4 4.3 0.0 26.1 1.5 24.1 1.4 27.2 2.2 2.7 5.7 3.8 0.6 1.8 5.0 1.1 0.1 0.7 1.2 0.9 2.4 10.2 9.8 3.2 2.3 0.2 0.7 0.0 2.1 7.2 0.1 5.8 20.5 2.8 3.2 0.0 2.2 0.0 0.0 7.2 1.8 0.7 0.1 2.4 12.1 8.8 1.8 0.8 0.0 0.0 4.1 9.1 2.5 4.4 0.2 11.1 3.2 27.3 0.4 2.4 0.0 3.7 41.7 0.0 4.2 48.2 0.0 0.2 17.0 1.6 0.0 0.2 1.2 0.3 99.3 13.8 0.3 0.0 0.1 0.1 0.0 4.5 8.8 7.1 1.0 5.2 0.4 1.7 0.0 0.0 17.8 4.2 1.0 0.0 0.0 0.0 0.4 0.0 0.6 0.1 0.5 0.5 0.1 0.7 0.3 0.1 0.5 0.2 0.0 0.1 0.2 0.1 5.1 10.2 0.0 17.0 13.7 0.0 0.0 0.0 0.0 0.6 0.1 3.2 0.9 0.0 0.5 2.3 8.2 0.6 3.4 0.4 0.0 271.5 0.1 0.4 1.8 0.0 5.2 1.8 2.1 0.0 2.5 0.0 0.0 0.0 1.5 0.3 6.5 2.2 0.0 2.5 29.9 0.2 0.2 8.8 0.0 0.5 0.0 0.1 0.0 0.0 0.5 3.3 2.0 0.2 2.0 1.2 6.2 6.7 3.1 5.9 1.8 3.7 0.9 6.1 2.1 7.1 17.0 0.7 0.0 3.4 2.7 3.7 0.0 0.2 5.0 11.6 0.0 4.2 2.9 0.3 0.4 0.0 0.1 0.1 5.0 0.1 0.0 0.6 PRR5 "FLJ20185k, PP610, Protor-1" ENSG00000186654 "Proline rich 5" P85299 22 44668547-44737681 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 91.3;NK-cells: 77.2;Proximal tubular cells: 55.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "monocytes: 19.1;T-cells: 28.6" "Cell line enhanced" "Detected in many" "U-266/70: 99.2;U-266/84: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054072 Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA054072: AB_2682369" "unprognostic (2.63e-2)" "unprognostic (6.63e-3)" "unprognostic (2.61e-2)" "prognostic favorable (2.47e-5)" "unprognostic (1.83e-2)" "unprognostic (3.99e-2)" "unprognostic (7.52e-2)" "unprognostic (1.37e-1)" "unprognostic (8.98e-2)" "unprognostic (5.13e-2)" "unprognostic (1.34e-1)" "unprognostic (2.36e-1)" "unprognostic (1.65e-1)" "unprognostic (2.48e-3)" "unprognostic (1.55e-1)" "unprognostic (1.09e-1)" "unprognostic (2.00e-1)" 16.2 2.4 7.2 3.2 7.7 7.2 12.2 5.9 11.3 8.4 11.9 6.0 8.6 3.8 2.1 7.6 4.3 2.9 3.5 7.9 9.7 11.5 18.5 3.5 3.9 8.1 8.2 4.0 6.2 2.3 16.1 4.5 8.5 7.9 2.4 0.4 5.7 3.8 0.8 7.4 9.4 1.1 5.9 20.5 5.2 5.1 10.5 2.3 4.5 1.2 2.5 6.9 7.1 5.8 8.1 9.6 2.0 6.8 0.2 0.3 25.0 7.0 6.2 4.2 3.4 24.4 3.4 0.0 5.2 8.2 4.9 7.2 2.1 7.1 0.7 0.2 19.9 15.9 1.3 28.5 5.8 2.9 5.8 2.9 7.9 0.4 2.2 1.0 0.2 3.7 10.1 0.5 0.9 21.4 1.1 4.6 1.3 11.4 1.4 0.7 4.5 14.5 1.4 3.8 7.0 1.0 1.9 11.4 9.5 5.5 5.3 2.8 0.0 0.1 11.0 1.0 0.1 99.2 31.3 0.2 0.0 6.4 0.8 0.5 0.3 0.1 24.8 3.4 28.6 1.6 8.3 18.8 0.7 0.9 3.5 13.0 0.6 5.6 19.1 0.4 14.8 6.8 7.2 7.7 5.9 11.3 7.9 9.7 8.1 8.2 8.5 5.9 10.5 5.8 6.0 0.0 3.9 11.4 9.2 8.3 12.0 2.1 4.0 0.7 13.6 13.2 2.0 10.0 2.3 5.5 0.0 32.1 50.3 20.5 5.9 5.2 0.5 4.4 5.4 12.5 9.6 91.3 2.0 7.9 3.3 23.2 8.2 4.7 7.6 5.4 21.4 19.9 32.1 0.0 1.8 22.8 2.0 13.5 8.2 0.5 5.3 7.7 8.8 3.7 3.0 6.0 77.2 1.0 0.2 8.4 7.6 3.8 29.0 24.2 50.9 55.2 1.4 1.5 0.0 11.4 5.3 0.3 20.4 8.0 8.5 44.1 37.1 51.8 25.5 13.5 PRR5L "FLJ14213, PROTOR-2" ENSG00000135362 "Proline rich 5 like" Q6MZQ0 11 36296288-36465204 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.9;intestine: 34.7;lymphoid tissue: 36.4" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 302.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 35.5;HMC-1: 55.7;hTERT-HME1: 57.9;SiHa: 40.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070174 Approved "Cytokinetic bridge,Cytosol" Yes No "Cluster 38: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cytokinetic bridge, Cytosol" "HPA070174: AB_2686231" "unprognostic (6.76e-2)" "unprognostic (1.61e-1)" "unprognostic (3.48e-2)" "prognostic favorable (7.30e-5)" "unprognostic (2.34e-2)" "unprognostic (1.21e-1)" "unprognostic (1.63e-1)" "unprognostic (7.45e-2)" "unprognostic (3.61e-1)" "unprognostic (1.46e-2)" "unprognostic (3.03e-3)" "unprognostic (2.12e-1)" "prognostic unfavorable (7.71e-8)" "prognostic unfavorable (4.86e-4)" "unprognostic (1.66e-1)" "unprognostic (1.44e-1)" "unprognostic (2.98e-2)" 3.6 1.5 10.1 8.9 27.8 4.7 2.7 21.7 16.7 11.4 2.2 34.7 3.3 2.8 2.0 1.4 6.3 7.1 2.0 9.6 21.1 7.7 2.9 13.6 9.3 36.6 23.8 12.8 1.2 0.9 2.7 3.6 33.9 2.4 27.8 0.7 7.8 2.0 0.9 1.7 12.2 5.9 24.1 36.4 3.4 1.5 23.9 3.4 3.2 0.7 3.3 4.3 3.8 46.9 0.0 5.5 10.3 0.2 1.4 0.0 0.1 13.2 8.9 25.7 27.2 0.0 0.2 0.1 4.4 15.7 5.9 0.5 2.1 5.9 12.9 5.0 3.7 1.5 35.5 0.0 3.5 0.0 55.7 3.8 9.0 2.3 57.9 25.2 9.4 0.0 0.0 0.1 13.6 3.3 0.7 0.1 0.8 0.1 2.3 4.1 1.1 1.1 27.0 6.9 0.0 0.4 40.1 0.0 2.2 6.5 0.0 0.6 7.8 22.3 6.8 0.0 16.4 0.2 0.0 0.0 9.7 1.5 6.7 36.1 2.0 24.9 34.6 21.4 8.2 0.0 12.2 29.7 2.5 1.6 2.6 18.0 11.8 9.6 24.6 7.7 0.0 15.4 10.1 27.8 21.7 16.7 9.6 21.1 36.6 23.8 33.9 24.1 23.9 46.9 2.1 19.2 4.2 17.6 0.7 0.4 0.2 5.0 0.0 0.1 1.9 0.9 0.9 1.5 6.8 7.3 0.0 0.2 25.9 44.3 1.9 1.3 17.6 1.5 0.8 7.7 1.8 7.0 1.8 2.2 0.1 2.1 1.1 2.5 5.1 0.5 22.5 0.4 8.8 0.0 1.1 22.7 10.2 11.7 0.7 54.9 0.6 5.4 0.0 16.9 4.7 1.2 58.7 31.7 302.0 3.9 37.0 0.4 4.2 0.7 13.2 0.5 9.0 0.2 6.6 1.8 2.6 0.3 0.6 0.4 0.6 0.3 14.5 0.9 17.5 0.5 PRRT1 "C6orf31, DSPD1, IFITMD7, NG5" ENSG00000204314 "Proline rich transmembrane protein 1" Q99946 6 32148359-32153083 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 40.1;ovary: 11.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 67.5;Cardiomyocytes: 125.5;Granulosa cells: 181.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 38.4;cerebral cortex: 40.1;hippocampal formation: 37.0;white matter: 17.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.0;SK-MEL-30: 1.6;U-2 OS: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055149, HPA059099" Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" "HPA055149: AB_2682717, HPA059099: AB_2732632" "unprognostic (1.40e-2)" "unprognostic (1.35e-1)" "unprognostic (2.10e-3)" "unprognostic (3.87e-3)" "unprognostic (2.89e-1)" "unprognostic (4.74e-2)" "unprognostic (5.51e-3)" "unprognostic (5.93e-2)" "unprognostic (1.49e-1)" "unprognostic (1.58e-2)" "unprognostic (8.08e-5)" "unprognostic (2.99e-1)" "unprognostic (2.22e-2)" "unprognostic (8.59e-2)" "unprognostic (9.40e-2)" "unprognostic (1.94e-1)" "unprognostic (1.78e-2)" 1.6 2.2 38.4 0.3 6.4 0.0 2.0 0.0 40.1 2.7 0.0 2.9 0.6 2.3 0.0 1.5 3.6 0.1 1.6 37.0 4.8 3.1 0.9 1.3 0.1 3.4 2.1 11.9 0.6 0.3 5.6 0.2 2.2 3.1 0.0 1.3 0.9 0.6 0.4 2.0 1.8 0.0 0.0 0.9 2.0 1.3 6.5 0.0 1.9 0.0 0.0 2.4 2.4 17.5 0.0 0.1 0.0 0.5 0.2 0.1 0.2 0.8 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.8 0.0 0.0 1.6 0.0 0.6 0.0 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.4 6.4 0.0 40.1 37.0 4.8 3.4 2.1 2.2 0.0 6.5 17.5 3.2 0.0 0.0 4.9 0.5 4.0 8.0 3.4 14.8 67.5 1.8 3.0 125.5 10.0 1.2 1.8 10.4 6.7 1.7 2.2 1.9 0.1 1.3 1.3 2.3 6.7 9.0 4.2 12.6 0.0 1.0 7.8 4.6 0.5 0.0 181.6 5.0 3.5 1.0 32.0 10.9 5.5 0.0 0.8 2.1 1.2 6.2 1.9 3.6 6.5 0.2 16.0 1.0 3.5 5.0 0.2 3.4 6.4 0.8 3.6 5.5 0.1 3.7 8.7 0.0 3.6 8.0 0.8 1.6 3.8 2.7 3.6 2.2 8.1 4.1 4.8 PTGES "MGST-IV, MGST1-L1, MGST1L1, PIG12, TP53I12" ENSG00000148344 "Prostaglandin E synthase" O14684 9 129738331-129753042 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 84.2;urinary bladder: 78.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 101.2;Cytotrophoblasts: 146.0;Extravillous trophoblasts: 293.1;Syncytiotrophoblasts: 276.2" "Cancer enhanced" "Detected in all" "urothelial cancer: 69.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "basophil: 28.9" "Lineage enriched" "Detected in many" 7 "granulocytes: 28.9" "Cell line enhanced" "Detected in many" "ASC diff: 147.7;BEWO: 162.7;GAMG: 292.8;HaCaT: 216.3;SK-BR-3: 157.6;U-2197: 404.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045064 Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "HPA045064: AB_10795889" "unprognostic (2.92e-3)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.32e-4)" "unprognostic (2.54e-2)" "unprognostic (1.94e-3)" "unprognostic (1.25e-1)" "unprognostic (5.38e-3)" "unprognostic (1.24e-3)" "unprognostic (2.92e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (7.97e-5)" "unprognostic (2.22e-1)" "unprognostic (4.66e-2)" "unprognostic (9.78e-3)" "unprognostic (3.19e-2)" "unprognostic (1.30e-1)" "unprognostic (5.20e-2)" 36.7 1.4 4.1 13.9 3.6 7.8 25.5 3.9 4.5 26.1 3.5 9.2 2.8 3.7 19.0 17.8 5.4 9.0 8.5 4.5 5.1 8.1 0.7 7.8 7.6 6.1 5.8 2.2 1.6 42.1 1.9 58.4 7.1 13.7 4.2 0.0 30.8 84.2 1.3 42.3 9.1 4.1 4.1 2.5 7.1 16.9 4.7 4.2 3.7 1.1 30.7 78.6 20.0 3.5 1.5 94.9 0.1 46.6 147.7 51.9 162.7 7.4 64.2 1.1 1.7 5.6 71.7 0.1 2.7 18.0 292.8 216.3 0.7 7.2 0.6 0.3 0.5 0.0 62.5 0.4 3.5 0.0 0.0 30.9 49.0 0.9 0.3 1.4 0.0 0.9 0.0 0.1 0.7 1.7 0.2 0.0 1.2 46.7 8.2 0.2 0.0 0.3 5.3 102.2 0.8 3.6 87.1 157.6 0.8 6.3 83.3 0.0 0.5 0.1 0.4 404.8 0.0 0.0 0.0 0.0 78.8 0.1 0.7 28.9 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 4.0 0.0 0.0 0.3 4.1 3.6 3.9 4.5 4.5 5.1 6.1 5.8 7.1 4.1 4.7 3.5 3.4 0.0 0.0 0.3 0.3 17.8 8.9 101.2 10.8 0.0 29.7 19.7 0.1 0.0 53.2 3.7 0.0 146.0 0.6 0.0 1.9 13.4 0.6 1.6 2.3 4.0 7.3 0.0 1.0 1.1 293.1 70.7 0.0 5.0 1.3 61.5 0.0 0.0 17.5 0.0 2.8 6.6 30.5 0.0 21.6 0.4 0.3 13.2 14.2 7.5 7.2 0.0 0.0 0.0 0.2 8.1 0.2 0.0 0.3 8.2 0.3 0.5 6.7 0.0 0.0 0.8 13.5 0.3 0.0 5.5 43.0 276.2 0.8 0.2 0.4 49.2 PTGFR FP ENSG00000122420 "Prostaglandin F receptor" P43088 1 78303884-78540701 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 20.1" "Cell type enhanced" "Detected in many" "Club cells: 14.3;Fibroblasts: 22.7;Inhibitory neurons: 10.4;Langerhans cells: 10.6;Microglial cells: 17.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "ASC TERT1: 271.2;HSkMC: 85.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.14e-2)" "unprognostic (1.35e-2)" "unprognostic (5.89e-3)" "unprognostic (6.03e-2)" "unprognostic (5.63e-2)" "unprognostic (1.45e-3)" "unprognostic (7.61e-2)" "unprognostic (2.25e-1)" "unprognostic (9.90e-2)" "unprognostic (8.46e-4)" "unprognostic (2.21e-1)" "unprognostic (5.34e-2)" "unprognostic (2.16e-4)" "unprognostic (3.21e-4)" "unprognostic (8.48e-2)" "unprognostic (2.16e-2)" "unprognostic (1.21e-3)" 9.9 3.4 0.6 5.7 0.4 0.0 7.2 0.1 1.8 4.6 0.3 2.0 1.0 17.9 2.4 0.9 4.6 6.9 1.7 1.9 2.7 3.9 1.3 2.5 1.2 0.7 0.5 4.6 0.9 0.0 0.2 8.1 1.8 3.1 2.7 0.2 4.7 2.0 2.1 5.2 2.4 16.7 0.4 0.6 1.6 1.4 3.5 0.1 0.8 20.1 4.3 11.9 4.4 0.2 0.0 0.0 1.0 0.0 26.5 271.2 0.0 20.5 20.0 7.0 2.7 0.0 0.0 0.0 0.0 12.4 3.8 0.0 0.0 0.1 6.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 85.7 0.0 1.8 17.6 18.3 0.1 0.0 0.0 0.7 10.9 0.0 0.0 0.0 0.1 0.0 15.9 0.0 0.0 0.0 2.4 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.2 5.9 8.5 4.7 2.1 1.6 1.1 0.0 0.0 0.5 0.0 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.1 1.8 1.9 2.7 0.7 0.5 1.8 0.4 3.5 0.2 1.2 0.0 8.0 0.3 0.0 6.4 0.0 1.0 0.0 1.2 0.2 0.0 0.4 5.7 14.3 9.2 0.0 0.1 0.0 0.0 3.9 4.2 8.5 0.4 0.6 0.6 0.0 0.0 0.4 0.0 0.0 22.7 0.5 0.1 0.0 0.1 0.0 2.3 0.1 0.0 10.4 0.0 0.0 0.0 10.6 9.3 5.6 0.4 5.4 17.8 0.0 0.3 0.0 0.0 0.2 0.0 1.1 0.4 0.2 0.1 0.0 0.3 6.3 0.0 6.6 7.1 1.4 1.1 0.2 0.1 4.7 0.3 0.5 0.3 0.0 0.0 PTGS1 "COX1, PGHS-1, PTGHS" ENSG00000095303 "Prostaglandin-endoperoxide synthase 1" P23219 9 122370530-122395703 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Dioxygenase, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 108.3;skin 1: 152.5;urinary bladder: 175.0" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 109.9;Glandular and luminal cells: 191.9;granulocytes: 208.0;Hepatic stellate cells: 61.8;Macrophages: 55.3;Suprabasal keratinocytes: 58.7" "Cancer enhanced" "Detected in all" "ovarian cancer: 53.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 28.9" "Group enriched" "Detected in many" 6 "dendritic cells: 20.0;granulocytes: 28.9;monocytes: 13.1" "Cell line enhanced" "Detected in many" "ASC diff: 113.7;ASC TERT1: 89.5;BJ: 115.2;BJ hTERT+: 156.0;HEL: 73.6;HMC-1: 298.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002834, CAB020315" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 2100000 "Cluster 2: Granulocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" Vesicles "CAB020315: , HPA002834: AB_1079711" "unprognostic (4.20e-1)" "unprognostic (6.23e-2)" "unprognostic (1.08e-2)" "unprognostic (2.27e-2)" "unprognostic (5.88e-2)" "unprognostic (2.00e-2)" "unprognostic (1.22e-3)" "unprognostic (3.32e-1)" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (1.23e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (4.03e-2)" "unprognostic (1.78e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (9.35e-4)" 12.8 2.9 3.1 10.5 3.2 9.0 6.7 4.2 4.8 5.8 5.5 108.3 10.8 6.1 2.2 67.3 43.2 9.6 12.6 7.4 5.5 9.3 3.0 11.3 4.6 6.5 5.2 2.0 1.8 2.0 4.8 2.2 6.3 21.1 24.2 0.7 4.3 6.1 2.1 152.5 17.7 16.1 6.7 8.0 20.5 0.9 7.0 2.2 3.2 4.0 11.6 175.0 15.9 11.9 0.3 0.5 0.4 0.0 113.7 89.5 0.0 115.2 156.0 1.0 1.1 0.0 0.2 4.2 5.4 19.7 0.3 7.1 0.4 10.5 0.9 0.0 0.2 73.6 0.6 0.0 32.9 5.2 298.4 46.1 1.2 5.7 0.3 0.0 42.3 0.1 0.1 0.3 2.3 0.0 0.2 6.6 1.6 0.0 0.5 0.3 1.4 8.6 14.7 0.0 0.5 0.6 0.6 9.5 0.2 0.5 0.3 8.4 1.0 0.7 0.6 1.7 0.1 0.3 0.2 0.0 0.4 31.6 0.3 28.9 12.1 23.3 0.0 13.1 0.0 2.4 0.0 0.0 20.0 3.5 0.1 0.0 5.2 2.8 10.2 1.4 0.2 21.9 3.1 3.2 4.2 4.8 7.4 5.5 6.5 5.2 6.3 6.7 7.0 11.9 0.9 0.0 6.6 0.0 5.9 9.9 2.6 7.7 0.0 0.1 1.1 1.4 1.6 4.3 2.2 42.3 0.0 0.1 0.2 0.1 0.0 0.6 0.1 109.9 10.4 24.7 1.8 18.7 0.8 0.5 0.3 10.7 2.0 191.9 208.0 0.1 61.8 0.8 26.1 0.0 0.5 0.6 4.1 15.5 20.7 0.3 1.5 55.3 3.6 16.9 11.7 0.0 7.2 1.0 0.1 0.6 0.6 0.0 0.3 2.8 0.0 0.0 0.8 0.1 0.0 1.4 3.6 0.0 0.2 18.2 58.7 0.4 3.4 0.1 1.0 0.8 PTGS2 COX2 ENSG00000073756 "Prostaglandin-endoperoxide synthase 2" P35354 1 186671791-186680922 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Dioxygenase, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 116.7;seminal vesicle: 127.4;urinary bladder: 162.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 342.9;Fibroblasts: 270.7;granulocytes: 347.6;Langerhans cells: 305.6;Macrophages: 173.1;Urothelial cells: 151.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 16 "neutrophil: 11.7" "Lineage enriched" "Detected in single" 16 "granulocytes: 11.7" "Cell line enriched" "Detected in many" 4 "BJ hTERT+: 405.5" "Region enhanced" "Detected in many" "hippocampal formation: 15.1" "Low region specificity" "Detected in many" "CAB000113, HPA001335" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum, Vesicles" "CAB000113: , HPA001335: AB_1079712" "unprognostic (1.36e-3)" "unprognostic (9.97e-3)" "unprognostic (3.97e-2)" "unprognostic (3.31e-2)" "unprognostic (1.55e-1)" "unprognostic (1.11e-1)" "unprognostic (5.96e-2)" "unprognostic (9.50e-2)" "unprognostic (9.03e-3)" "unprognostic (2.81e-1)" "unprognostic (3.24e-2)" "unprognostic (3.07e-2)" "prognostic unfavorable (9.79e-4)" "unprognostic (8.04e-3)" "unprognostic (4.38e-2)" "unprognostic (8.89e-2)" "unprognostic (3.74e-2)" 17.0 7.9 1.4 13.9 2.5 116.7 3.0 1.1 4.1 62.2 2.7 14.9 2.6 8.9 0.7 6.9 5.1 31.6 11.7 1.9 1.4 10.2 8.0 34.3 8.9 2.0 1.6 2.6 2.2 5.6 3.1 8.4 1.5 25.0 9.9 0.3 1.2 127.4 0.4 1.6 3.6 12.2 1.9 2.8 14.8 0.2 1.8 5.2 3.2 6.5 0.6 162.5 2.2 2.6 0.0 21.8 0.1 0.0 2.5 2.1 0.0 93.4 405.5 0.6 3.6 15.0 17.2 0.0 0.0 0.1 2.5 12.2 0.0 7.6 1.3 0.0 0.0 0.8 2.2 0.0 13.2 0.0 0.2 0.8 2.7 11.3 28.7 1.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.8 0.0 0.0 0.0 0.0 0.0 5.5 1.5 0.0 1.0 0.0 0.9 2.7 0.0 0.1 1.5 19.3 0.6 13.5 0.6 0.2 0.0 0.0 27.7 0.4 2.3 0.0 0.3 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 11.7 0.0 0.4 0.0 0.0 0.0 1.4 2.5 1.1 4.1 1.9 1.4 2.0 1.6 1.5 1.9 1.8 2.6 5.2 342.9 77.7 0.0 7.4 118.8 59.1 72.8 12.5 0.0 2.6 12.8 2.5 0.0 79.7 0.0 0.0 0.2 4.2 0.3 0.0 0.8 0.2 50.0 9.9 31.1 1.2 3.6 3.8 0.2 0.3 270.7 2.0 98.9 347.6 3.8 13.6 0.2 12.1 0.0 1.0 1.0 8.2 21.0 305.6 0.0 0.0 173.1 35.6 3.7 3.4 0.1 0.0 0.0 0.1 4.9 0.1 0.0 2.0 122.6 0.2 0.3 13.1 0.3 0.0 1.8 12.8 0.1 0.4 3.3 28.4 0.5 10.8 3.7 1.2 151.6 PTN "HBGF8, HBNF, NEGF1" ENSG00000105894 Pleiotrophin P21246 7 137227341-137343774 "Cancer-related genes, Predicted secreted proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 280.4;parathyroid gland: 383.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 672.0;Extravillous trophoblasts: 416.0;Horizontal cells: 526.6;Muller glia cells: 548.5;Oligodendrocyte precursor cells: 322.7;Squamous epithelial cells: 439.9" "Cancer enriched" "Detected in all" 11 "glioma: 514.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 12 "AF22: 1717.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017685, HPA073913" Enhanced Supported "Endoplasmic reticulum" "Secreted to blood" NA NA 167000 1400000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: NES - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" "Endoplasmic reticulum" "CAB017685: AB_1128556, HPA073913: " "unprognostic (1.51e-2)" "unprognostic (7.87e-2)" "unprognostic (5.44e-2)" "unprognostic (4.23e-2)" "unprognostic (1.92e-1)" "unprognostic (7.19e-2)" "unprognostic (2.81e-2)" "unprognostic (7.29e-2)" "unprognostic (1.30e-1)" "unprognostic (1.09e-2)" "unprognostic (3.86e-1)" "unprognostic (1.22e-2)" "prognostic favorable (1.35e-4)" "unprognostic (2.34e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (1.16e-2)" 26.2 18.2 212.9 4.1 206.4 0.1 82.3 217.0 280.4 100.0 182.0 31.4 5.4 76.8 55.3 78.2 19.2 55.9 87.7 209.6 205.2 38.4 8.5 18.4 7.4 220.3 200.5 19.0 8.4 383.5 126.1 36.2 196.3 116.1 21.6 63.4 37.4 52.5 2.2 9.1 10.1 54.0 204.2 40.4 15.7 53.8 207.6 21.4 18.9 18.8 11.4 24.8 65.1 209.1 1.2 0.0 1717.6 21.2 0.4 0.9 140.6 45.3 134.3 25.1 34.3 0.4 0.2 0.0 0.2 60.0 15.6 1.0 0.0 0.0 18.9 0.0 1.4 0.0 0.0 0.0 7.7 0.0 0.5 1.9 0.0 16.6 0.2 24.6 0.0 0.0 0.0 8.2 7.0 0.0 0.0 0.6 133.5 0.0 1.1 0.1 2.8 0.4 0.7 0.0 8.0 116.5 0.0 0.0 0.2 24.1 0.2 0.2 0.0 37.4 32.9 1.8 99.4 0.7 0.0 0.0 119.7 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 212.9 206.4 217.0 280.4 209.6 205.2 220.3 200.5 196.3 204.2 207.6 209.1 10.1 0.0 0.0 303.3 1.3 23.2 1.7 85.0 209.5 27.7 244.6 117.3 14.6 2.8 20.9 1.8 6.2 220.0 2.2 0.0 9.8 1.1 24.5 53.4 672.0 32.0 0.0 0.0 4.9 0.0 416.0 248.8 0.5 24.6 0.0 1.1 7.1 0.3 20.4 526.6 18.1 0.0 0.0 0.3 20.6 14.0 172.7 4.0 44.4 102.1 0.0 548.5 0.0 322.7 218.4 0.3 0.0 185.5 2.5 18.6 0.0 7.5 7.2 32.3 59.2 3.0 91.4 4.0 2.4 439.9 13.9 193.3 4.4 144.7 0.0 2.2 PTPRN2 "IA-2beta, ICAAR, KIAA0387, phogrin" ENSG00000155093 "Protein tyrosine phosphatase receptor type N2" Q92932 7 157539056-158587823 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Protein phosphatase, Receptor" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.9;pancreas: 98.1" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 131.1;Excitatory neurons: 439.6;Inhibitory neurons: 433.4;Oligodendrocyte precursor cells: 138.2" "Cancer enhanced" "Detected in all" "prostate cancer: 40.8" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 23.6" "Lineage enriched" "Detected in all" 4 "granulocytes: 23.6" "Cell line enhanced" "Detected in many" "AF22: 45.5;HDLM-2: 42.0;MOLT-4: 22.1;NB-4: 43.0;SCLC-21H: 23.8;SH-SY5Y: 25.4;U-87 MG: 27.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006900, HPA007255, HPA026656" Enhanced Approved Vesicles NA NA 1600000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA006900: AB_1079715, HPA007255: , HPA026656: AB_1855912" "unprognostic (2.42e-1)" "unprognostic (4.17e-2)" "unprognostic (7.82e-2)" "unprognostic (2.69e-2)" "prognostic unfavorable (9.37e-5)" "unprognostic (7.12e-3)" "unprognostic (1.04e-1)" "unprognostic (4.55e-2)" "unprognostic (4.27e-2)" "unprognostic (1.64e-1)" "unprognostic (1.20e-2)" "unprognostic (1.39e-1)" "prognostic favorable (8.68e-4)" "unprognostic (2.60e-2)" "unprognostic (1.48e-1)" "unprognostic (1.43e-3)" "unprognostic (6.16e-2)" 3.8 16.5 29.4 2.7 34.3 1.3 2.9 0.0 49.9 2.1 0.0 7.7 8.3 3.0 4.2 1.9 10.8 7.6 3.1 35.2 22.7 3.9 1.6 4.8 3.4 7.9 3.1 8.7 98.1 1.0 41.0 2.1 3.4 17.3 6.1 9.2 12.9 3.6 1.2 0.8 6.7 2.1 0.1 13.4 40.2 6.2 14.1 1.6 8.7 1.9 2.5 4.2 2.1 20.5 0.1 0.4 45.5 3.6 0.1 0.2 0.1 0.4 0.3 0.0 0.1 0.0 4.0 0.0 1.2 0.5 9.4 0.3 1.0 0.0 0.0 42.0 0.8 0.0 0.0 7.3 1.1 0.0 0.1 2.0 0.8 0.1 0.5 0.3 0.0 3.4 0.1 0.3 0.0 0.7 22.1 43.0 5.7 13.7 3.2 0.0 2.7 0.2 0.2 0.0 23.8 25.4 0.0 0.1 0.0 0.0 0.0 20.9 6.2 9.2 4.3 0.1 1.5 0.3 0.1 0.0 27.7 17.4 6.8 14.1 1.5 2.8 1.3 0.2 0.5 3.5 2.1 1.4 2.1 4.2 2.4 1.4 23.6 2.4 0.0 0.6 5.3 1.3 29.4 34.3 0.0 49.9 35.2 22.7 7.9 3.1 3.4 0.1 14.1 20.5 40.7 3.2 12.9 16.3 18.4 2.3 12.7 1.3 4.0 30.2 1.9 2.2 3.1 10.0 9.1 40.5 10.4 0.4 8.7 5.9 35.2 22.9 51.9 8.7 2.5 26.3 131.1 6.6 439.6 13.1 0.4 13.0 41.8 0.8 19.0 14.1 44.3 0.8 44.5 11.8 433.4 43.3 6.1 7.0 11.3 19.3 12.5 7.9 12.4 27.2 5.7 67.3 15.5 138.2 11.0 7.3 7.0 19.5 5.4 15.0 6.5 3.8 52.6 8.0 26.3 1.4 7.0 62.8 16.3 4.8 1.4 0.7 14.8 32.7 9.7 24.8 PTPRT "KIAA0283, RPTPrho" ENSG00000196090 "Protein tyrosine phosphatase receptor type T" O14522 20 42072752-43189970 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 23.9;fallopian tube: 10.8" "Group enriched" "Detected in some" 14 "Excitatory neurons: 500.7;Inhibitory neurons: 700.2;Oligodendrocyte precursor cells: 418.7" "Group enriched" "Detected in many" 5 "breast cancer: 5.1;prostate cancer: 1.9" "Region enhanced" "Detected in many" "cerebral cortex: 23.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "BEWO: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017336, CAB069423" Approved NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB069423: AB_1622602, HPA017336: AB_1855943" "unprognostic (7.17e-3)" "unprognostic (1.02e-1)" "unprognostic (5.61e-3)" "unprognostic (1.08e-2)" "unprognostic (5.95e-2)" "unprognostic (3.71e-2)" "unprognostic (1.97e-1)" "unprognostic (1.31e-2)" "unprognostic (6.93e-2)" "unprognostic (2.00e-1)" "unprognostic (1.37e-6)" "unprognostic (3.16e-1)" "unprognostic (1.13e-2)" "unprognostic (1.81e-1)" "unprognostic (3.17e-1)" "unprognostic (1.10e-1)" "unprognostic (1.17e-1)" 0.1 0.2 10.1 0.1 10.7 0.0 2.7 0.0 23.9 0.6 0.0 0.1 0.5 0.0 0.2 0.0 10.8 0.1 0.2 7.4 0.0 0.1 0.2 1.0 0.4 0.1 0.0 0.0 0.4 0.0 3.0 2.8 0.0 0.2 0.0 3.6 1.0 2.6 0.0 0.4 0.3 0.0 0.0 0.1 0.8 1.6 0.0 6.3 0.0 0.1 0.4 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 10.7 0.0 23.9 7.4 0.0 0.1 0.0 0.0 0.0 0.0 5.0 0.4 0.0 1.1 13.1 0.0 0.9 0.0 0.0 0.0 36.2 2.6 6.9 1.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 3.2 0.1 0.2 0.0 0.0 500.7 0.0 0.0 1.2 0.0 0.2 0.0 3.3 6.4 0.2 0.2 5.0 700.2 0.0 0.0 0.3 0.3 12.6 0.0 0.1 0.0 8.4 0.0 10.3 0.0 418.7 8.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 18.5 2.1 0.0 0.5 0.2 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 RAB34 "NARR, RAB39, RAH" ENSG00000109113 "RAB34, member RAS oncogene family" "P0DI83, Q9BZG1" 17 28714281-28718429 "Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Peritubular cells: 169.7;Theca cells: 182.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 51.0;intermediate monocyte: 47.2;myeloid DC: 76.3;non-classical monocyte: 23.4;plasmacytoid DC: 46.6" "Group enriched" "Detected in all" 5 "dendritic cells: 76.3;monocytes: 51.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021366 Approved NA NA 1100000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" "HPA021366: AB_1856003" "unprognostic (1.29e-3)" "unprognostic (1.77e-1)" "unprognostic (7.87e-2)" "unprognostic (2.38e-1)" "unprognostic (2.35e-2)" "unprognostic (7.75e-2)" "unprognostic (1.33e-1)" "unprognostic (1.36e-3)" "unprognostic (2.21e-1)" "unprognostic (5.62e-2)" "unprognostic (8.77e-2)" "unprognostic (4.15e-2)" "prognostic unfavorable (1.64e-7)" "unprognostic (1.31e-3)" "unprognostic (7.72e-2)" "prognostic favorable (1.06e-5)" "unprognostic (5.05e-2)" 50.4 86.3 24.7 25.0 24.5 21.3 45.4 23.9 26.6 96.1 31.8 76.8 13.4 80.5 60.2 32.1 74.6 54.2 52.3 22.8 23.7 77.1 7.2 43.6 26.2 26.9 24.6 104.6 7.1 66.2 30.8 32.7 24.7 70.6 21.4 3.8 28.4 78.2 11.0 37.9 31.1 75.0 24.6 30.2 37.6 11.0 25.9 25.9 52.9 17.8 23.5 78.6 60.5 23.4 143.2 203.2 109.4 314.4 129.9 206.3 38.2 184.1 299.0 200.3 166.9 1.7 51.1 0.4 171.5 310.1 69.6 87.7 1.9 104.6 159.7 10.8 94.7 99.2 141.0 11.3 152.0 1.0 0.7 187.7 63.3 151.8 127.9 237.7 138.8 0.4 0.5 1.2 201.6 0.0 0.6 0.2 108.9 0.1 53.7 20.2 261.9 0.7 189.6 73.5 26.8 0.2 134.2 0.6 227.2 93.1 79.0 55.2 31.5 144.0 192.4 132.1 181.9 0.2 0.9 1.5 158.3 0.6 144.8 7.0 51.0 3.1 3.0 47.2 0.7 11.4 5.4 4.2 76.3 11.8 11.7 10.5 1.7 1.1 23.4 46.6 5.8 21.7 24.7 24.5 23.9 26.6 22.8 23.7 26.9 24.6 24.7 24.6 25.9 23.4 37.0 35.3 44.7 42.1 9.7 52.9 105.1 145.0 33.0 2.6 31.2 65.9 8.7 10.0 56.2 57.0 0.0 49.8 12.8 0.2 95.9 3.9 1.1 49.8 79.5 29.3 0.0 12.6 0.1 3.8 102.3 124.2 2.0 34.1 71.5 84.1 25.4 0.3 41.7 1.7 1.2 0.5 59.0 60.5 82.9 5.6 148.8 43.5 65.8 5.6 40.5 25.3 1.0 6.0 0.1 2.0 0.0 169.7 4.6 82.1 0.1 44.6 45.3 2.5 32.9 81.1 98.3 1.9 4.6 20.6 35.4 58.8 10.8 182.1 0.4 59.0 RAB36 ENSG00000100228 "RAB36, member RAS oncogene family" O95755 22 23145326-23164350 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 32.8" "Group enriched" "Detected in many" 4 "Endometrial ciliated cells: 41.2;Late spermatids: 24.5;Respiratory ciliated cells: 69.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 11.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 11.0" "Cell line enhanced" "Detected in many" "RPMI-8226: 25.5;U-266/84: 26.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059631 Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 25: RPMI-8226 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA059631: " "unprognostic (2.74e-2)" "unprognostic (1.32e-3)" "unprognostic (2.06e-2)" "unprognostic (1.23e-2)" "unprognostic (1.15e-2)" "unprognostic (6.60e-2)" "unprognostic (1.22e-1)" "unprognostic (3.46e-1)" "unprognostic (2.49e-2)" "unprognostic (7.94e-2)" "unprognostic (2.02e-3)" "unprognostic (5.56e-3)" "prognostic favorable (4.55e-4)" "unprognostic (7.08e-2)" "unprognostic (7.18e-2)" "unprognostic (1.64e-1)" "unprognostic (3.08e-1)" 2.0 5.1 8.8 1.3 8.7 0.7 2.6 3.8 8.4 5.1 21.7 3.2 0.7 4.8 4.4 2.1 32.8 5.3 1.4 9.9 9.1 9.1 0.4 4.8 1.1 9.4 11.2 6.2 3.4 5.6 17.1 2.9 6.9 3.9 1.1 2.0 3.3 6.6 0.6 1.8 1.2 3.8 7.9 1.6 2.1 6.7 10.4 0.3 17.6 0.4 1.3 2.5 2.1 5.1 8.1 9.4 7.1 10.7 1.6 3.4 2.8 4.5 9.1 9.8 3.7 0.6 0.0 0.0 4.8 6.0 5.4 10.0 0.3 5.2 3.1 0.0 4.3 0.1 0.4 0.9 4.1 0.0 1.2 4.3 1.9 9.1 1.8 6.4 1.4 0.0 0.4 8.1 0.4 6.4 0.1 0.1 0.9 5.3 2.5 0.0 0.0 25.5 12.7 1.5 17.3 7.5 0.4 3.9 2.2 0.5 0.0 0.9 0.8 1.3 2.9 3.4 6.5 17.3 26.2 0.1 8.8 0.0 5.8 0.3 0.6 0.0 0.5 0.2 0.3 0.8 0.1 0.2 0.2 0.2 0.3 0.3 11.0 1.6 0.3 0.0 0.0 0.3 8.8 8.7 3.8 8.4 9.9 9.1 9.4 11.2 6.9 7.9 10.4 5.1 0.6 0.0 3.2 3.6 1.4 0.5 0.8 4.2 0.0 0.7 1.8 2.8 0.8 4.3 7.0 1.8 6.2 6.0 0.3 0.0 5.9 3.5 10.6 41.2 2.9 0.7 6.7 0.0 2.9 0.2 0.4 2.0 1.5 2.6 1.3 2.4 1.1 0.1 0.4 1.7 1.7 0.7 6.1 0.8 0.3 24.5 3.4 0.3 1.8 1.0 0.5 3.6 1.0 1.5 1.0 0.2 0.2 3.0 0.3 0.4 0.0 9.6 69.6 0.7 0.0 1.0 2.0 3.6 1.6 0.5 0.1 2.9 0.4 4.5 0.3 0.4 RADIL "FLJ10324, KIAA1849, RASIP2" ENSG00000157927 "Rap associating with DIL domain" Q96JH8 7 4797055-4883716 "Predicted intracellular proteins" "Cell adhesion" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.0" "Cell type enhanced" "Detected in many" "Astrocytes: 10.1;Early spermatids: 9.2;Horizontal cells: 13.5;Microglial cells: 14.0;Spermatocytes: 17.0;Spermatogonia: 11.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 7.8;HEK 293: 6.5;NTERA-2: 7.3;SCLC-21H: 8.9;SH-SY5Y: 19.0;U-2197: 6.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051776 Approved Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear membrane" "HPA051776: AB_2681605" "unprognostic (6.77e-2)" "unprognostic (1.07e-1)" "unprognostic (5.61e-2)" "unprognostic (1.80e-2)" "unprognostic (1.80e-2)" "unprognostic (1.21e-1)" "unprognostic (9.74e-4)" "unprognostic (4.63e-2)" "unprognostic (3.48e-1)" "unprognostic (2.83e-2)" "unprognostic (7.89e-4)" "unprognostic (5.32e-2)" "unprognostic (1.49e-4)" "unprognostic (5.10e-3)" "unprognostic (2.46e-1)" "unprognostic (3.33e-3)" "unprognostic (4.28e-3)" 3.4 0.5 2.2 0.2 1.9 0.0 3.3 11.0 3.6 4.1 0.4 3.4 0.2 3.2 0.2 0.8 3.7 0.7 4.8 1.8 4.0 0.4 0.1 4.5 0.1 3.3 3.7 1.5 3.3 0.3 2.9 2.6 3.4 2.0 0.2 0.3 1.1 1.2 2.8 1.2 1.3 1.0 2.8 0.5 1.3 8.2 2.7 0.2 2.5 2.0 0.1 2.3 2.9 1.7 0.0 2.1 4.4 7.8 0.2 1.9 0.0 1.0 0.1 0.1 0.2 0.0 0.0 0.0 0.2 0.8 1.5 0.0 3.2 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 1.7 4.2 0.0 0.4 1.9 0.0 0.0 7.3 0.1 1.6 5.0 0.5 0.0 0.0 0.0 8.9 19.0 0.0 0.0 0.0 1.8 3.2 0.6 0.0 0.0 0.0 6.1 1.9 0.2 0.4 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.9 11.0 3.6 1.8 4.0 3.3 3.7 3.4 2.8 2.7 1.7 1.8 3.2 1.5 10.1 0.0 0.8 0.0 0.0 0.6 2.1 3.4 1.8 2.3 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 9.2 1.1 2.6 2.2 0.0 0.0 2.6 1.7 0.0 3.9 0.0 0.1 0.0 0.2 0.4 0.0 0.1 13.5 3.6 0.3 0.0 0.6 1.2 5.1 3.4 1.0 7.2 14.0 0.0 4.7 0.0 7.1 3.5 0.3 0.1 3.8 0.0 0.4 0.0 0.0 1.5 0.9 6.6 4.7 4.1 17.0 11.7 0.0 0.6 0.1 2.1 0.3 0.0 0.0 RCE1 "FACE-2, FACE2, hRCE1, RCE1A, RCE1B" ENSG00000173653 "Ras converting CAAX endopeptidase 1" Q9Y256 11 66842835-66846552 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074124 Approved NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "HPA074124: " "unprognostic (1.11e-1)" "unprognostic (7.23e-2)" "unprognostic (1.15e-1)" "unprognostic (8.16e-3)" "unprognostic (3.11e-1)" "unprognostic (6.40e-3)" "unprognostic (1.98e-3)" "unprognostic (7.69e-3)" "unprognostic (1.39e-1)" "unprognostic (9.14e-3)" "unprognostic (2.35e-3)" "unprognostic (5.31e-3)" "unprognostic (1.06e-1)" "unprognostic (4.48e-3)" "unprognostic (2.17e-2)" "unprognostic (1.04e-1)" "unprognostic (4.28e-2)" 10.1 10.9 14.9 7.2 15.1 20.9 9.3 17.9 18.2 10.7 13.7 13.3 10.1 8.4 5.9 19.9 8.9 8.6 7.3 14.7 14.9 25.7 7.9 8.9 9.9 14.0 14.1 10.8 15.5 9.5 13.9 11.8 14.2 12.0 8.2 10.0 12.6 6.1 4.4 19.9 12.4 5.9 13.5 12.0 12.0 13.5 15.5 9.5 7.0 4.2 6.1 11.9 12.9 14.6 22.7 24.5 14.7 13.8 9.0 7.8 32.3 11.6 11.2 17.7 15.8 46.6 47.2 17.2 21.8 11.1 29.3 39.6 17.1 17.4 10.2 20.7 19.3 15.5 17.0 18.0 31.7 20.3 22.0 12.6 32.7 19.9 17.6 13.7 14.6 23.5 21.7 26.0 9.0 42.8 28.2 38.3 43.5 43.1 24.0 22.9 11.0 34.1 19.5 12.0 18.3 16.5 16.8 22.3 74.1 14.3 26.2 16.3 9.7 24.2 18.7 26.4 18.5 14.6 15.2 19.6 16.4 20.8 18.4 23.1 21.1 14.6 17.1 24.0 15.6 15.3 14.7 22.1 18.9 12.0 11.8 17.8 7.2 14.3 21.5 29.1 6.7 17.8 14.9 15.1 17.9 18.2 14.7 14.9 14.0 14.1 14.2 13.5 15.5 14.6 12.5 0.0 4.8 4.2 16.9 31.2 26.6 46.2 14.2 9.2 16.4 20.6 1.8 10.0 20.3 16.5 29.2 54.6 24.9 12.4 3.9 24.3 10.1 11.3 12.5 12.2 10.7 10.7 7.7 27.4 65.0 12.0 11.7 17.1 8.2 13.3 8.2 3.0 22.8 3.3 6.2 16.0 26.4 8.9 15.1 20.2 6.8 13.3 14.2 3.7 12.9 6.4 9.2 6.0 4.0 30.0 18.0 6.4 14.5 19.6 23.2 7.4 8.9 18.0 13.1 5.6 32.1 9.7 25.7 17.1 24.9 58.6 19.1 10.3 16.2 23.9 RERG MGC15754 ENSG00000134533 "RAS like estrogen regulated growth inhibitor" Q96A58 12 15107783-15348675 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 104.7" "Cell type enhanced" "Detected in many" "Astrocytes: 202.7;Breast glandular cells: 80.1;Inhibitory neurons: 94.3;Sertoli cells: 92.1;Smooth muscle cells: 80.2" "Cancer enhanced" "Detected in all" "breast cancer: 19.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 15.2;BEWO: 34.1;T-47d: 66.0;U-2 OS: 21.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041387 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center" "HPA041387: AB_10796669" "unprognostic (5.33e-2)" "unprognostic (1.05e-1)" "unprognostic (7.72e-2)" "prognostic unfavorable (7.56e-4)" "unprognostic (8.72e-2)" "unprognostic (9.42e-3)" "unprognostic (2.47e-1)" "unprognostic (2.38e-2)" "unprognostic (1.85e-3)" "unprognostic (2.76e-2)" "unprognostic (5.07e-2)" "unprognostic (2.69e-1)" "unprognostic (7.16e-3)" "unprognostic (2.61e-3)" "unprognostic (3.30e-2)" "unprognostic (3.50e-1)" "unprognostic (2.58e-2)" 30.7 45.4 8.9 6.8 21.0 0.0 42.5 5.9 16.3 32.0 3.5 37.0 4.1 104.7 50.3 15.1 72.7 11.2 14.0 10.2 12.3 37.0 2.5 16.5 4.3 20.7 12.8 29.0 9.8 4.8 1.4 33.3 21.2 17.0 9.3 0.8 10.2 77.5 5.4 10.2 18.0 83.9 7.7 31.4 20.1 9.0 12.8 2.6 5.8 5.8 2.7 17.4 20.0 9.0 0.0 1.6 0.3 15.2 6.0 0.3 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 6.9 0.0 0.1 0.0 0.2 0.2 0.0 0.0 4.3 0.1 5.9 0.0 4.7 0.0 1.9 0.8 1.0 0.0 2.3 0.0 0.0 0.0 0.6 0.0 1.4 0.7 0.2 0.3 1.7 0.0 0.9 0.1 0.0 0.2 5.8 0.3 0.1 2.2 2.5 2.6 0.0 1.0 66.0 0.0 0.0 0.9 21.5 0.4 0.0 0.1 5.7 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 21.0 5.9 16.3 10.2 12.3 20.7 12.8 21.2 7.7 12.8 9.0 10.7 0.0 2.2 202.7 0.4 3.8 8.6 0.9 6.2 1.3 80.1 36.2 1.0 5.7 4.0 7.3 0.0 12.0 0.7 0.0 15.6 9.8 20.9 6.5 9.8 6.0 1.8 0.0 20.2 9.8 14.6 28.7 2.6 1.0 0.0 0.1 2.2 0.0 2.1 3.3 94.3 0.0 18.3 0.0 2.3 16.1 22.1 1.1 7.2 41.2 0.0 5.0 0.0 3.0 1.1 2.2 0.0 32.0 0.0 3.5 0.0 33.7 0.1 0.5 92.1 8.2 80.2 8.3 15.0 12.6 5.5 14.0 1.2 16.1 0.0 5.8 RGS4 SCZD9 ENSG00000117152 "Regulator of G protein signaling 4" P49798 1 163068775-163076802 "Disease related genes, Predicted intracellular proteins" "Signal transduction inhibitor" Schizophrenia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 34.6;brain: 120.6" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 51.6;Excitatory neurons: 115.4;Inhibitory neurons: 59.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 120.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "hTERT-RPE1: 527.4;LHCN-M2: 244.2;SH-SY5Y: 429.5;TIME: 959.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030802 Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA030802: AB_10602295" "unprognostic (1.03e-1)" "unprognostic (1.84e-1)" "unprognostic (3.02e-2)" "unprognostic (6.84e-2)" "prognostic unfavorable (2.62e-4)" "unprognostic (8.26e-2)" "unprognostic (1.27e-1)" "unprognostic (5.34e-3)" "unprognostic (1.82e-1)" "unprognostic (6.45e-2)" "unprognostic (2.12e-2)" "unprognostic (8.47e-2)" "prognostic unfavorable (3.97e-4)" "prognostic unfavorable (1.92e-4)" "unprognostic (1.00e-1)" "unprognostic (8.33e-2)" "unprognostic (2.30e-2)" 8.2 34.6 35.6 3.0 46.7 0.0 1.7 0.0 120.6 5.9 0.0 4.3 4.2 7.8 1.2 9.7 7.3 18.3 8.7 49.3 42.2 1.9 4.0 3.0 3.7 0.0 5.2 2.2 4.7 2.3 14.3 1.6 2.0 4.7 2.5 6.7 0.8 6.5 0.4 0.3 2.8 4.7 0.0 1.7 8.4 3.0 0.0 1.8 3.1 1.4 0.4 5.9 1.4 39.7 0.3 0.0 1.2 7.2 25.1 115.9 0.2 77.8 92.1 12.6 31.9 0.0 0.3 0.3 35.6 50.2 0.5 0.2 0.0 0.1 42.2 0.4 0.1 0.3 0.0 0.0 11.0 0.2 0.2 19.0 0.0 123.0 14.3 527.4 127.5 0.0 0.1 0.6 244.2 0.0 0.0 0.5 6.5 0.0 9.6 0.1 0.0 0.4 0.0 0.0 2.9 429.5 0.0 0.1 0.2 4.0 0.1 0.1 959.6 91.5 5.2 19.1 129.5 0.1 0.1 0.3 11.4 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.6 46.7 0.0 120.6 49.3 42.2 0.0 5.2 2.0 0.0 0.0 39.7 0.8 0.0 0.0 15.7 0.0 0.3 1.7 0.1 0.0 4.3 0.7 0.0 0.7 0.0 0.7 0.0 0.0 0.2 0.1 0.1 0.0 0.3 12.6 0.5 16.9 2.6 51.6 0.0 115.4 0.2 0.1 20.2 0.0 0.4 0.0 1.1 1.1 0.0 0.4 0.0 59.9 0.0 0.0 0.0 0.5 3.8 0.0 0.1 0.0 13.1 0.0 15.7 0.0 13.0 13.0 2.7 0.1 0.0 0.0 0.5 0.0 0.0 0.7 1.6 0.0 0.2 17.0 0.1 0.6 0.5 0.3 0.1 0.6 0.1 0.1 0.3 RHOJ "ARHJ, FLJ14445, RASL7B, TCL" ENSG00000126785 "Ras homolog family member J" Q9H4E5 14 63204114-63293508 "Predicted intracellular proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 41.0;Astrocytes: 176.0;Endothelial cells: 72.5;Hepatic stellate cells: 41.4;Microglial cells: 35.6;Oligodendrocyte precursor cells: 43.2;Skeletal myocytes: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 63.8;HUVEC TERT2: 375.4;TIME: 100.9;WM-115: 106.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003050 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA003050: AB_1079812" "unprognostic (7.24e-2)" "unprognostic (1.72e-1)" "unprognostic (4.37e-2)" "unprognostic (2.42e-1)" "unprognostic (6.71e-2)" "unprognostic (1.77e-2)" "unprognostic (2.89e-1)" "unprognostic (2.33e-2)" "unprognostic (2.19e-1)" "unprognostic (3.04e-3)" "unprognostic (1.42e-2)" "unprognostic (7.07e-2)" "prognostic unfavorable (1.31e-4)" "unprognostic (3.50e-3)" "unprognostic (4.84e-2)" "unprognostic (1.86e-2)" "unprognostic (1.06e-3)" 19.6 3.3 12.5 8.5 14.6 0.1 17.4 10.8 16.9 12.9 8.5 14.2 7.5 27.9 17.3 15.5 18.5 25.3 17.9 14.0 11.1 11.7 4.2 21.5 9.6 10.9 11.0 14.2 4.4 3.5 6.4 9.3 11.0 11.8 10.7 5.5 8.4 13.8 7.9 7.6 9.8 31.4 8.3 12.6 9.3 2.8 14.5 3.1 13.8 13.4 4.9 19.7 9.4 13.0 0.0 0.0 63.8 0.0 0.0 0.0 0.0 10.6 42.6 3.6 6.2 0.0 0.0 0.0 5.9 0.8 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.1 0.3 0.0 0.1 8.0 35.8 375.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.4 0.0 5.1 0.0 0.4 0.0 0.1 0.1 0.0 0.0 14.6 1.1 0.1 0.0 100.9 0.1 1.1 0.8 6.1 0.0 0.0 0.0 0.0 0.0 106.5 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 12.5 14.6 10.8 16.9 14.0 11.1 10.9 11.0 11.0 8.3 14.5 13.0 41.0 0.0 1.3 176.0 0.3 5.9 0.3 0.1 0.0 0.3 1.2 5.2 3.8 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 1.4 0.5 0.3 6.7 72.5 0.0 0.0 11.1 0.9 0.0 31.0 0.0 0.3 0.0 0.5 41.4 0.5 0.1 0.0 2.2 0.0 0.0 1.9 7.7 1.6 11.8 1.0 3.6 35.6 0.0 11.1 0.0 43.2 0.4 0.1 0.0 16.1 2.5 0.6 0.0 0.0 0.0 0.4 6.6 34.6 17.0 0.1 0.4 0.9 4.8 0.1 0.6 6.9 0.0 1.4 RNASE4 RAB1 ENSG00000258818 "Ribonuclease A family member 4" P34096 14 20684560-20701216 "Plasma proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 478.8" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 67.3;Gastric mucus-secreting cells: 47.4;Hepatocytes: 55.8;Intestinal goblet cells: 110.0" "Cancer enhanced" "Detected in many" "liver cancer: 6.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 92.6;ASC TERT1: 107.2;Hep G2: 136.9;HSkMC: 63.1;OE19: 92.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 61000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 27: Mucus-secreting cells - Mucin production" "unprognostic (1.07e-1)" "unprognostic (3.46e-1)" "unprognostic (5.21e-2)" "unprognostic (3.18e-4)" "unprognostic (1.20e-1)" "unprognostic (7.05e-2)" "prognostic favorable (9.62e-5)" "unprognostic (1.43e-1)" "unprognostic (2.22e-2)" "unprognostic (6.88e-2)" "unprognostic (3.71e-2)" "unprognostic (1.29e-1)" "unprognostic (3.46e-1)" "unprognostic (2.54e-2)" "unprognostic (1.57e-1)" "unprognostic (9.16e-2)" "unprognostic (4.27e-2)" 106.4 7.8 5.5 8.9 5.7 1.2 96.6 5.4 8.3 95.6 8.5 56.5 22.0 59.2 37.0 20.1 77.3 55.6 44.1 5.5 8.1 40.3 478.8 40.3 12.2 6.9 6.6 111.7 41.0 14.7 12.5 5.7 6.9 76.7 65.2 4.7 74.8 45.8 14.1 47.4 41.9 25.9 6.7 11.8 84.7 10.6 5.3 5.8 26.5 31.5 10.6 65.3 75.9 7.8 2.7 12.1 2.6 0.1 92.6 107.2 0.5 10.5 23.8 1.4 4.5 3.4 4.1 0.1 2.9 24.6 6.2 2.5 1.4 2.6 1.7 17.2 1.8 0.3 2.9 136.9 10.2 1.3 0.6 63.1 5.8 1.6 10.3 34.6 12.6 4.2 0.1 12.2 6.9 1.5 1.0 0.2 0.5 92.3 10.3 0.6 2.1 3.6 2.9 2.4 0.1 0.5 5.0 2.3 2.6 4.2 3.4 0.2 13.3 3.0 1.7 4.1 0.3 2.6 3.5 0.4 4.7 1.3 2.7 0.2 24.1 0.1 0.8 1.2 1.0 5.3 1.5 0.6 13.8 4.9 0.3 0.6 0.6 0.6 0.1 3.3 3.3 8.4 5.5 5.7 5.4 8.3 5.5 8.1 6.9 6.6 6.9 6.7 5.3 7.8 1.8 38.5 19.1 2.0 3.4 2.8 1.7 2.5 11.4 0.0 9.9 2.5 0.2 28.6 4.7 3.7 0.0 0.2 0.3 30.4 0.0 34.4 0.2 0.1 0.8 4.0 67.3 8.4 0.1 22.2 0.4 39.2 47.4 0.8 1.3 0.3 5.0 55.8 1.6 0.0 0.2 110.0 2.0 6.2 4.0 0.3 12.5 3.6 3.6 1.9 2.7 1.3 1.0 0.0 0.9 12.8 33.2 4.1 5.9 1.7 41.7 10.2 11.6 0.3 0.0 2.6 8.1 0.2 0.1 10.2 4.1 0.4 0.8 0.1 39.6 1.5 RNF112 "BFP, ZNF179" ENSG00000128482 "Ring finger protein 112" Q9ULX5 17 19411125-19417276 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Neurogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.8" "Cell type enhanced" "Detected in some" "Astrocytes: 8.1;Bipolar cells: 6.6;Excitatory neurons: 19.6;Inhibitory neurons: 11.6;Muller glia cells: 7.6;Oligodendrocyte precursor cells: 13.6;Sertoli cells: 6.6" "Cancer enriched" "Detected in some" 8 "glioma: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.2;fHDF/TERT166: 6.2;SCLC-21H: 6.0;SH-SY5Y: 10.6;U-87 MG: 34.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA015970 Enhanced Approved "Nuclear speckles" NA NA "Cluster 65: Brain - Ion transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "HPA015970: AB_1859103" "unprognostic (1.16e-1)" "unprognostic (3.74e-1)" "unprognostic (8.43e-5)" "unprognostic (3.65e-2)" "unprognostic (2.96e-2)" "unprognostic (6.02e-2)" "unprognostic (1.27e-1)" "unprognostic (2.88e-1)" "unprognostic (4.26e-1)" "unprognostic (5.02e-2)" "unprognostic (3.17e-1)" "unprognostic (2.96e-1)" "unprognostic (1.31e-9)" "unprognostic (1.32e-1)" "unprognostic (1.07e-1)" "unprognostic (1.59e-1)" "unprognostic (4.24e-1)" 2.2 5.4 20.2 1.5 21.9 0.1 1.9 33.8 25.0 3.2 7.2 9.4 1.8 3.0 4.5 1.7 3.2 2.8 3.6 24.7 16.8 3.9 1.0 2.8 0.7 12.7 14.2 2.4 1.3 0.0 5.5 0.5 14.0 12.3 2.8 1.5 1.2 2.0 1.3 1.9 6.9 2.2 12.9 3.0 2.5 2.3 16.6 0.2 2.2 1.3 0.2 8.4 3.2 23.2 0.0 0.0 0.1 0.4 1.4 5.2 0.2 0.3 1.2 0.1 0.0 0.2 0.0 0.0 0.1 6.2 0.0 0.2 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 4.2 0.0 0.1 2.1 0.2 0.2 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.4 0.1 0.2 0.2 0.0 0.0 6.0 10.6 0.1 0.0 0.0 1.4 0.1 0.1 0.1 0.0 0.3 0.6 0.0 0.1 0.0 0.0 34.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.2 21.9 33.8 25.0 24.7 16.8 12.7 14.2 14.0 12.9 16.6 23.2 1.1 0.0 0.0 8.1 0.0 1.0 0.0 0.2 0.0 6.6 0.1 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.1 0.2 0.3 0.5 0.0 0.0 19.6 0.0 0.0 3.3 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 11.6 0.2 0.0 0.6 0.4 0.2 0.0 0.3 0.0 4.7 0.1 7.6 1.0 13.6 3.3 0.0 1.4 3.8 0.0 0.2 0.5 0.0 0.1 0.7 6.6 1.4 1.5 1.7 0.7 0.3 1.0 0.3 0.2 0.0 0.1 0.1 RPP25 FLJ20374 ENSG00000178718 "Ribonuclease P and MRP subunit p25" Q9BUL9 15 74954418-74956772 "Enzymes, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 95.1;Hofbauer cells: 77.0;Rod photoreceptor cells: 72.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 25.8" "Group enriched" "Detected in many" 5 "dendritic cells: 25.8;monocytes: 10.1" "Cell line enhanced" "Detected in many" "HHSteC: 46.0;SCLC-21H: 42.9;SK-MEL-30: 67.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "olfactory bulb: 23.0" HPA046900 Approved Supported "Nucleoplasm,Centriolar satellite" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "Centriolar satellite" "HPA046900: AB_10962049" "unprognostic (9.36e-2)" "unprognostic (7.17e-3)" "unprognostic (5.54e-2)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (7.18e-2)" "unprognostic (5.73e-3)" "unprognostic (5.50e-3)" "unprognostic (7.78e-2)" "unprognostic (1.44e-1)" "unprognostic (3.58e-2)" "unprognostic (1.70e-1)" "unprognostic (4.71e-3)" "unprognostic (5.50e-3)" "unprognostic (5.58e-2)" "unprognostic (1.10e-1)" "unprognostic (2.53e-1)" 6.0 13.2 7.4 2.7 8.9 0.4 4.5 14.6 8.5 7.1 6.5 7.9 7.2 3.7 1.8 6.9 4.4 4.5 5.5 4.9 10.8 5.1 3.1 5.8 3.9 16.5 12.7 15.4 7.6 23.0 5.2 7.2 16.4 4.2 4.8 12.8 4.6 1.7 1.4 4.9 5.7 2.5 10.8 10.8 7.1 3.0 12.8 2.4 8.9 1.5 3.4 7.7 5.4 12.7 23.6 17.5 4.4 0.1 1.5 0.9 7.4 4.3 5.2 1.3 1.2 24.1 21.0 0.0 19.4 4.4 1.2 6.9 13.7 0.8 0.3 8.9 0.7 0.1 19.9 0.5 46.0 0.0 13.3 5.9 0.6 8.5 0.0 0.9 20.4 5.5 16.1 0.0 4.6 9.1 3.8 6.3 20.8 40.9 7.0 0.1 0.0 15.8 4.2 0.4 42.9 32.1 32.6 28.8 67.4 2.2 5.7 18.7 4.6 0.0 1.4 3.8 0.2 0.4 0.1 0.1 2.3 36.6 25.1 0.0 5.2 0.0 2.3 10.1 1.3 3.4 1.5 1.8 5.1 3.7 3.8 3.0 0.4 0.5 7.7 25.8 0.7 2.5 7.4 8.9 14.6 8.5 4.9 10.8 16.5 12.7 16.4 10.8 12.8 12.7 5.3 3.2 1.1 0.3 4.9 11.0 7.5 9.1 11.4 95.1 11.8 9.9 1.6 14.3 6.4 9.2 4.2 2.3 17.0 24.4 13.7 13.7 0.3 1.6 4.7 8.9 10.2 0.8 0.7 19.3 4.3 23.9 14.8 3.6 0.0 3.4 31.8 1.6 77.0 21.9 10.0 12.5 14.2 14.8 8.6 2.6 39.4 9.3 14.2 1.0 16.1 13.4 4.1 0.0 6.3 13.8 20.5 30.1 8.2 19.1 27.5 16.6 1.3 72.3 13.1 4.3 10.4 1.4 6.5 18.2 11.5 2.3 2.1 26.6 20.7 10.5 RTN4RL2 "NgR2, NGRH1" ENSG00000186907 "Reticulon 4 receptor like 2" Q86UN3 11 57460528-57477534 "Plasma proteins, Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 39.1;liver: 40.7;thyroid gland: 30.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 19.9;Cholangiocytes: 12.8;Excitatory neurons: 16.7;Hepatocytes: 14.0;Oligodendrocyte precursor cells: 9.5;Spermatocytes: 10.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HMC-1: 44.1;Karpas-707: 67.5;REH: 42.3;RPMI-8226: 134.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 9 "amygdala: 13.5;cerebral cortex: 23.8;hippocampal formation: 21.0" "Intracellular and membrane" NA NA 27000000 "Cluster 7: Monocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (6.27e-3)" "unprognostic (2.02e-2)" "unprognostic (4.57e-2)" "unprognostic (8.40e-2)" "unprognostic (8.51e-2)" "unprognostic (7.64e-2)" "unprognostic (6.83e-2)" "unprognostic (3.72e-2)" "unprognostic (7.27e-2)" "unprognostic (2.41e-1)" "unprognostic (1.09e-2)" "unprognostic (3.28e-1)" "prognostic unfavorable (3.05e-7)" "unprognostic (3.53e-2)" "unprognostic (1.40e-1)" "unprognostic (5.16e-3)" "unprognostic (2.18e-2)" 4.1 0.7 19.0 0.3 39.1 0.8 3.5 0.0 27.3 2.1 0.0 1.0 1.1 2.0 0.2 1.6 1.7 3.0 3.3 25.2 0.0 2.8 40.7 2.6 0.4 0.0 0.0 1.1 2.4 3.7 3.6 1.9 0.0 1.6 0.1 1.0 3.4 0.3 1.7 4.3 1.1 0.7 0.0 1.0 1.5 1.8 0.0 1.9 30.5 0.4 0.3 1.2 1.6 8.2 7.4 10.1 7.6 13.1 3.1 4.4 1.0 0.1 2.9 0.3 2.7 1.3 1.4 0.2 0.2 0.4 4.3 0.2 11.9 0.2 0.1 1.7 4.7 2.3 1.1 7.2 4.4 1.7 44.1 11.9 1.3 1.1 1.1 1.3 0.1 12.9 1.6 67.5 0.1 1.4 0.2 5.3 13.3 0.5 7.6 42.3 5.4 134.0 0.1 0.2 14.0 1.2 1.1 0.6 7.7 0.6 8.5 2.0 0.1 0.5 22.7 3.1 2.4 4.1 9.2 1.4 16.7 7.3 5.8 0.0 0.3 0.0 0.0 0.6 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 19.0 39.1 0.0 27.3 25.2 0.0 0.0 0.0 0.0 0.0 0.0 8.2 1.7 0.0 0.0 2.0 0.4 5.7 0.4 0.3 2.8 19.9 2.1 1.5 0.4 12.8 0.1 0.0 0.0 0.0 0.9 0.2 3.9 1.3 2.6 0.6 0.9 2.1 1.8 0.8 16.7 0.6 5.5 1.6 0.5 2.1 0.0 0.0 1.1 14.0 0.4 0.0 1.1 0.6 0.0 0.0 2.1 1.3 0.3 0.6 1.8 3.7 0.5 0.8 2.1 9.5 1.2 0.8 0.1 1.2 0.0 1.0 0.0 1.1 0.0 1.4 6.6 1.0 5.4 10.2 1.7 1.1 2.8 0.0 0.9 0.1 0.2 0.2 SCARA3 "APC7, CSR, CSR1, MSLR1, MSRL1" ENSG00000168077 "Scavenger receptor class A member 3" Q6AZY7 8 27633868-27676776 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 136.5" "Cell type enhanced" "Detected in many" "Astrocytes: 238.6;Collecting duct cells: 66.2;Cytotrophoblasts: 45.8;Muller glia cells: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 179.9;HeLa: 203.2;HUVEC TERT2: 140.1;U-2 OS: 120.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029861, HPA047386" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "HPA029861: AB_2673225, HPA047386: AB_2680024" "unprognostic (2.24e-1)" "unprognostic (5.36e-3)" "unprognostic (2.68e-3)" "unprognostic (1.36e-1)" "unprognostic (1.48e-2)" "unprognostic (1.17e-1)" "unprognostic (4.31e-1)" "unprognostic (1.60e-1)" "unprognostic (3.58e-2)" "unprognostic (1.45e-1)" "unprognostic (3.80e-1)" "unprognostic (1.66e-1)" "unprognostic (3.41e-2)" "unprognostic (1.78e-2)" "unprognostic (4.95e-2)" "unprognostic (6.31e-3)" "unprognostic (6.03e-3)" 23.8 7.2 53.4 15.7 58.6 0.0 17.6 55.6 57.8 58.7 29.9 34.5 5.0 87.9 9.5 23.7 86.8 30.5 13.9 50.3 68.1 11.3 3.9 15.2 13.4 136.5 89.5 13.8 4.1 1.5 9.6 19.5 79.2 25.6 8.5 8.8 35.7 66.5 2.6 17.5 15.4 68.1 80.3 2.8 14.7 3.2 79.2 15.9 51.3 8.0 23.0 31.1 20.7 71.4 1.8 61.0 9.4 0.2 49.9 179.9 40.0 23.8 38.2 25.8 19.1 22.7 15.8 0.0 52.7 50.3 21.1 44.5 0.1 44.9 12.7 0.2 5.1 17.8 203.2 0.8 5.3 0.0 0.1 75.6 2.9 40.2 2.3 35.0 140.1 4.6 0.0 0.2 15.0 11.8 0.2 0.1 12.3 0.0 22.3 0.1 0.0 0.3 8.2 27.4 0.2 5.9 5.7 32.0 0.1 4.8 31.1 0.5 49.9 20.7 120.1 77.2 12.8 0.1 0.1 0.2 35.7 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.4 58.6 55.6 57.8 50.3 68.1 136.5 89.5 79.2 80.3 79.2 71.4 2.3 0.0 0.5 238.6 0.0 3.6 16.2 4.8 14.8 1.0 12.6 19.8 2.2 8.6 6.0 66.2 0.0 45.8 0.6 0.1 0.0 0.4 2.9 3.8 10.1 6.4 0.0 0.0 38.4 0.8 20.4 25.1 1.5 2.0 0.0 5.3 15.4 0.4 4.7 0.0 30.4 0.1 0.0 0.3 2.1 1.3 15.8 0.5 17.8 21.5 0.6 52.4 0.0 19.1 18.1 2.2 0.1 6.4 0.0 5.4 0.0 0.0 6.5 1.5 6.6 1.8 14.7 0.2 1.5 6.2 3.8 8.2 0.3 1.9 0.3 10.3 SCARF2 "HUMZD58C02, SREC-II, SREC2" ENSG00000244486 "Scavenger receptor class F member 2" Q96GP6 22 20424584-20437826 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 44.8;Fibroblasts: 21.2;Leydig cells: 13.4;Peritubular cells: 17.7;Sertoli cells: 13.1;Smooth muscle cells: 19.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 25.5;SH-SY5Y: 28.5;SK-MEL-30: 31.7;U-138 MG: 38.7;U-2 OS: 40.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA035079 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 580000 "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 9: U-2 OS - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "Nuclear bodies, Cytosol" "HPA035079: AB_10670287" "unprognostic (2.12e-1)" "unprognostic (2.16e-2)" "unprognostic (2.06e-2)" "unprognostic (1.06e-3)" "unprognostic (2.29e-1)" "unprognostic (2.92e-1)" "unprognostic (7.68e-2)" "unprognostic (7.87e-2)" "unprognostic (8.27e-2)" "unprognostic (2.18e-2)" "unprognostic (1.68e-1)" "unprognostic (2.94e-1)" "prognostic unfavorable (2.78e-5)" "unprognostic (4.38e-3)" "unprognostic (3.18e-2)" "unprognostic (3.00e-3)" "prognostic unfavorable (4.28e-4)" 15.1 5.4 2.4 1.9 2.6 0.4 10.7 0.5 3.3 19.1 4.1 10.0 1.3 22.4 0.5 3.6 15.5 3.6 10.3 2.1 3.9 10.6 3.6 23.2 1.3 5.1 3.2 20.2 4.0 0.4 5.4 3.7 2.2 15.5 0.3 0.1 4.6 4.5 3.1 10.1 6.0 2.2 2.0 9.4 7.8 2.7 4.7 0.2 11.8 0.4 0.2 13.3 13.2 1.3 0.7 0.4 5.8 10.1 3.4 4.8 2.3 25.5 10.8 6.2 3.3 0.1 0.1 0.4 14.6 12.7 0.4 0.2 3.4 0.1 0.7 0.9 21.6 2.1 0.5 4.9 21.3 0.0 1.1 8.2 0.1 3.0 1.5 3.0 3.0 0.1 0.2 0.2 2.2 1.1 0.0 0.5 7.8 0.0 3.3 0.6 16.1 0.0 0.1 0.1 2.5 28.5 0.1 0.0 31.7 1.1 0.9 0.1 3.7 38.7 40.7 1.0 5.9 1.2 0.5 0.4 0.1 0.5 19.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.4 2.6 0.5 3.3 2.1 3.9 5.1 3.2 2.2 2.0 4.7 1.3 3.6 0.0 0.0 1.6 0.1 2.8 1.6 0.7 0.0 2.9 0.3 0.9 44.8 0.0 0.3 0.0 2.1 0.4 0.3 0.1 0.0 0.0 0.3 2.6 8.9 10.5 0.0 0.0 1.9 0.0 1.6 21.2 1.5 1.0 0.0 0.6 3.9 0.7 0.7 0.0 5.2 0.2 0.0 0.8 2.4 0.5 13.4 0.4 3.6 6.5 0.0 0.3 1.0 3.0 1.1 0.0 0.1 17.7 0.2 7.1 0.0 0.2 4.2 0.8 13.1 1.4 19.5 1.1 0.7 0.3 2.7 0.4 1.2 2.1 0.2 0.6 SCUBE2 "Cegb1, Cegf1, FLJ16792" ENSG00000175356 "Signal peptide, CUB domain and EGF like domain containing 2" Q9NQ36 11 9019476-9138114 "Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 48.8" "Cell type enhanced" "Detected in many" "Adipocytes: 30.3;Basal prostatic cells: 51.4;Breast glandular cells: 45.0;Breast myoepithelial cells: 31.5;Prostatic glandular cells: 39.8" "Cancer enhanced" "Detected in all" "breast cancer: 54.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "non-classical monocyte: 1.0" "Lineage enriched" "Detected in single" 6 "monocytes: 1.0" "Cell line enhanced" "Detected in some" "HAP1: 5.7;SK-MEL-30: 8.1;T-47d: 28.4" "Group enriched" "Detected in some" 4 "olfactory bulb: 4.6;thalamus: 2.7" "Low region specificity" "Detected in all" "HPA006353, HPA029871" Uncertain "Secreted to blood" NA NA 1100000 "Cluster 7: Monocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" "HPA006353: AB_1856642, HPA029871: AB_10602299" "prognostic favorable (2.41e-4)" "unprognostic (5.72e-3)" "unprognostic (2.91e-1)" "unprognostic (1.76e-2)" "unprognostic (2.73e-1)" "unprognostic (6.12e-4)" "unprognostic (3.11e-1)" "unprognostic (6.39e-2)" "unprognostic (2.08e-1)" "unprognostic (9.39e-2)" "unprognostic (1.54e-2)" "unprognostic (3.04e-1)" "unprognostic (1.94e-2)" "unprognostic (9.12e-4)" "unprognostic (4.35e-1)" "unprognostic (5.94e-2)" "unprognostic (2.88e-1)" 14.8 2.0 3.5 3.7 3.5 0.0 32.2 13.7 3.1 17.6 0.2 11.1 3.6 13.4 48.8 4.5 18.2 7.9 4.3 4.0 4.9 1.3 0.9 4.6 3.9 3.0 3.6 0.9 22.0 19.5 9.6 22.5 3.7 33.3 4.5 1.9 2.3 8.7 9.0 12.3 16.3 13.0 5.4 5.0 21.4 2.2 4.7 2.4 5.2 6.2 7.6 28.6 6.9 5.1 0.0 0.1 1.5 0.9 0.5 0.6 0.2 1.6 0.8 0.9 0.6 0.3 0.0 0.0 0.6 3.9 0.1 0.0 5.7 0.0 1.4 0.1 0.3 0.0 0.0 0.0 0.6 0.0 0.1 1.3 0.0 0.4 0.0 0.3 0.6 0.0 0.0 0.0 1.1 0.0 0.0 1.3 0.9 0.0 0.0 0.1 0.0 0.2 0.4 3.1 0.7 1.0 1.1 0.1 8.1 1.3 28.4 0.0 0.0 0.6 0.4 0.6 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.5 3.5 13.7 3.1 4.0 4.9 3.0 3.6 3.7 5.4 4.7 5.1 30.3 16.0 9.2 1.6 0.0 7.4 51.4 0.3 1.2 0.4 45.0 31.5 0.6 0.0 5.6 1.8 0.0 0.2 0.1 1.0 0.0 0.1 3.4 2.2 8.8 3.3 1.2 0.0 3.1 1.8 0.2 9.4 0.0 6.4 0.0 0.3 1.1 0.1 0.8 13.5 14.9 5.2 6.1 0.3 1.5 2.5 0.3 0.7 19.6 5.6 0.1 0.0 0.0 13.6 4.6 0.1 4.3 0.7 0.0 39.8 0.6 0.0 1.5 0.3 0.0 5.2 1.5 0.6 0.7 0.1 1.8 0.4 0.3 6.6 9.6 15.6 SERPING1 "C1-INH, C1IN, C1INH, C1NH, HAE1, HAE2" ENSG00000149131 "Serpin family G member 1" P05155 11 57597387-57619171 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Complement pathway, Fibrinolysis, Hemostasis, Immunity, Innate immunity" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 2622.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 726.4;Ductal cells: 604.0;Fibroblasts: 793.6;Hepatocytes: 2530.0;Leydig cells: 735.3" "Cancer enhanced" "Detected in all" "liver cancer: 609.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 65.2;plasmacytoid DC: 60.6" "Group enriched" "Detected in many" 243 "dendritic cells: 60.6;granulocytes: 65.2;monocytes: 25.7" "Group enriched" "Detected in many" 6 "ASC diff: 1372.2;ASC TERT1: 694.9;HSkMC: 1159.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 194.1" "CAB026161, HPA048738" Supported "Secreted to blood" NA NA 28000000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "CAB026161: , HPA048738: AB_2680505" "unprognostic (1.35e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (9.96e-4)" "unprognostic (4.26e-2)" "unprognostic (4.38e-2)" "unprognostic (2.32e-1)" "unprognostic (4.12e-3)" "unprognostic (2.13e-1)" "unprognostic (8.95e-2)" "prognostic favorable (8.03e-4)" "unprognostic (5.92e-3)" "unprognostic (3.76e-2)" "prognostic unfavorable (1.55e-4)" "unprognostic (2.60e-2)" "unprognostic (4.14e-2)" "unprognostic (2.56e-1)" "unprognostic (1.17e-1)" 971.5 144.2 27.4 90.0 27.5 10.9 733.0 27.1 36.0 629.4 53.4 358.7 52.0 616.7 163.3 162.0 793.2 533.0 547.1 26.2 34.8 337.3 2622.4 785.0 147.6 67.4 34.7 918.3 267.5 55.2 138.2 198.9 34.2 329.3 97.0 34.5 250.5 258.1 151.8 293.5 283.5 226.8 42.3 240.7 344.8 50.6 37.2 36.1 338.2 173.4 64.4 555.9 519.8 35.1 0.0 0.0 48.2 0.0 1372.2 694.9 7.3 74.2 57.0 16.8 30.7 2.5 0.0 0.0 96.7 42.1 0.0 0.0 0.4 4.7 9.4 0.0 0.1 33.7 0.0 1.7 170.3 0.9 5.4 1159.0 15.5 5.7 0.2 6.0 0.0 0.0 1.0 0.0 1.0 0.0 0.0 1.3 46.6 0.0 0.0 4.3 4.0 0.7 7.4 0.0 0.2 14.4 0.3 0.0 0.9 41.8 0.2 3.3 0.0 0.8 21.2 0.7 0.0 0.2 0.4 0.6 0.2 0.5 0.0 0.0 18.3 0.3 0.0 25.7 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 65.2 0.2 11.5 60.6 0.0 5.7 27.4 27.5 27.1 36.0 26.2 34.8 67.4 34.7 34.2 42.3 37.2 35.1 162.1 118.6 110.8 5.5 8.0 75.8 61.2 7.1 24.5 0.8 24.2 57.7 28.7 726.4 57.5 158.2 0.0 37.1 15.3 0.0 43.0 604.0 4.8 76.0 297.4 150.5 0.0 69.2 3.6 44.0 93.4 793.6 8.6 69.6 7.6 8.3 260.5 2530.0 43.6 0.0 6.2 0.1 2.0 118.9 94.2 25.6 735.3 46.9 90.7 15.9 10.4 57.2 0.0 3.5 0.5 41.4 0.0 228.7 4.5 32.4 0.0 53.5 23.1 4.5 269.5 143.6 259.6 2.5 10.4 9.0 59.5 25.2 16.8 3.4 0.0 37.4 SEZ6L ENSG00000100095 "Seizure related 6 homolog like" Q9BYH1 22 26169462-26383597 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 60.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 222.1;Inhibitory neurons: 137.7;Oligodendrocyte precursor cells: 586.1" "Group enriched" "Detected in some" 6 "glioma: 14.6;pancreatic cancer: 3.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 5.9;myeloid DC: 5.7;non-classical monocyte: 5.3" "Group enriched" "Detected in many" 58 "dendritic cells: 5.7;monocytes: 5.9" "Group enriched" "Detected in some" 6 "SCLC-21H: 39.9;SH-SY5Y: 10.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045135 Approved Vesicles NA NA 6700000 "Cluster 51: Monocytes - Innate immune response" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA045135: AB_2732518" "unprognostic (1.01e-2)" "unprognostic (1.03e-1)" "unprognostic (1.37e-1)" "unprognostic (4.95e-2)" "unprognostic (4.49e-2)" "unprognostic (6.47e-2)" "unprognostic (4.19e-1)" "unprognostic (1.09e-2)" "unprognostic (5.02e-2)" "unprognostic (7.22e-2)" "unprognostic (1.39e-3)" "unprognostic (7.80e-2)" "unprognostic (2.40e-6)" "unprognostic (4.52e-2)" "unprognostic (3.89e-1)" "unprognostic (2.39e-4)" "unprognostic (3.18e-1)" 0.1 10.0 25.0 0.5 37.5 0.2 0.0 8.9 50.6 1.1 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.1 1.3 60.8 52.0 0.0 0.0 0.2 0.0 24.5 23.6 0.0 1.5 0.0 5.8 0.0 19.0 0.2 0.2 4.5 0.2 0.1 0.1 0.3 0.4 0.3 4.0 0.2 1.4 0.3 49.0 0.9 0.1 0.0 0.0 0.1 0.1 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.9 10.7 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 5.9 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.5 25.0 37.5 8.9 50.6 60.8 52.0 24.5 23.6 19.0 4.0 49.0 24.9 0.0 0.0 0.0 21.9 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 1.1 0.2 0.0 0.4 222.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 21.9 137.7 0.0 0.0 0.0 2.1 2.0 0.6 1.5 0.0 10.3 3.5 0.7 0.0 586.1 5.5 0.6 0.0 0.4 0.0 0.1 0.0 0.1 0.0 1.2 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 SH2D2A "F2771, TSAd" ENSG00000027869 "SH2 domain containing 2A" Q9NP31 1 156806243-156816848 "Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 33.9;dendritic cells: 139.5;NK-cells: 113.3;T-cells: 103.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 30 "NK-cells: 28.5;T-cells: 66.5" "Cell line enhanced" "Detected in many" "HDLM-2: 46.5;HMC-1: 33.3;Karpas-707: 81.0;RPMI-8226: 24.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "cerebral cortex: 3.5;hippocampal formation: 1.6" HPA074482 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA074482: " "prognostic favorable (4.96e-4)" "unprognostic (2.76e-2)" "unprognostic (7.50e-2)" "unprognostic (3.03e-3)" "unprognostic (1.14e-3)" "unprognostic (2.73e-1)" "unprognostic (3.11e-1)" "unprognostic (9.80e-2)" "unprognostic (3.08e-1)" "unprognostic (1.64e-1)" "unprognostic (9.34e-3)" "unprognostic (1.70e-1)" "prognostic unfavorable (5.26e-12)" "unprognostic (1.67e-1)" "unprognostic (2.09e-1)" "unprognostic (1.79e-1)" "prognostic favorable (1.31e-4)" 3.5 0.9 1.0 11.4 1.1 4.3 1.3 3.8 1.6 1.8 1.9 2.2 2.5 1.7 0.3 1.2 1.5 3.3 2.5 0.9 1.5 2.5 2.2 5.4 9.4 1.9 1.1 0.6 1.0 0.3 1.8 0.8 1.5 2.5 2.0 3.4 0.9 0.7 0.4 0.4 5.4 1.6 1.2 13.0 2.9 0.3 1.1 14.9 1.6 0.0 5.9 3.7 1.2 1.3 2.6 0.4 0.0 0.0 0.0 0.0 4.3 0.1 0.0 0.0 0.0 1.7 2.4 0.0 6.8 0.0 0.0 0.0 0.4 1.3 0.1 46.5 0.1 6.8 0.5 0.9 0.2 0.4 33.3 0.5 0.0 0.2 3.3 0.0 0.3 11.8 1.9 81.0 0.0 0.2 5.9 0.7 4.9 4.1 8.3 0.9 0.0 24.5 0.1 0.3 7.5 0.0 1.6 0.9 0.8 0.5 0.2 1.3 2.2 0.0 0.0 0.3 0.5 11.6 16.6 8.3 0.0 6.9 0.2 1.0 0.1 0.0 66.5 0.0 61.8 1.1 27.6 40.8 0.1 0.3 10.4 27.2 1.5 28.5 0.2 0.1 34.1 18.6 1.0 1.1 3.8 1.6 0.9 1.5 1.9 1.1 1.5 1.2 1.1 1.3 1.2 3.2 2.3 0.0 4.6 2.2 0.3 0.4 1.2 33.9 1.0 1.9 0.9 0.0 1.3 0.0 0.0 0.1 139.5 1.2 0.0 0.3 0.2 0.2 2.5 0.6 1.2 6.1 0.0 0.6 1.0 4.8 9.2 0.5 8.2 0.3 1.8 0.9 1.1 0.0 0.0 0.9 0.0 1.9 2.1 0.0 0.0 4.1 0.0 1.9 1.1 1.3 113.3 0.0 0.5 6.1 1.4 0.0 24.2 0.5 0.3 0.2 0.7 1.6 0.0 0.5 2.9 0.1 4.9 3.0 1.3 0.1 103.2 0.1 1.8 0.5 SHFL "C19orf66, FLJ11286, IRAV, RyDEN, SFL" ENSG00000130813 "Shiftless antiviral inhibitor of ribosomal frameshifting" Q9NUL5 19 10086122-10093252 "Predicted intracellular proteins" "Antiviral defense" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 75.7" "Cell type enhanced" "Detected in some" "Adipocytes: 23.3;dendritic cells: 21.7;Fibroblasts: 6.8;Hofbauer cells: 32.6;Plasma cells: 9.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 71.8;BJ hTERT+ SV40 Large T+ RasG12V: 81.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042001 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 15: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Cytosol "HPA042001: AB_10794167" "prognostic favorable (4.04e-4)" "unprognostic (1.21e-2)" "unprognostic (2.39e-3)" "unprognostic (2.03e-1)" "unprognostic (2.19e-2)" "unprognostic (2.00e-2)" "unprognostic (1.46e-1)" "unprognostic (3.93e-1)" "unprognostic (6.57e-2)" "unprognostic (4.22e-3)" "unprognostic (2.34e-1)" "unprognostic (1.88e-1)" "prognostic unfavorable (8.96e-11)" "unprognostic (5.92e-2)" "unprognostic (1.81e-1)" "unprognostic (4.41e-3)" "prognostic favorable (1.35e-4)" 12.8 18.5 27.1 14.2 27.4 15.7 12.2 26.3 30.1 17.0 24.4 12.8 14.8 15.8 16.5 8.6 17.6 18.1 8.2 27.2 28.5 14.0 75.7 16.8 22.8 27.3 27.0 18.9 9.9 16.7 14.1 12.7 27.2 11.9 9.9 15.0 16.3 19.1 4.4 9.5 18.4 15.4 28.8 19.9 11.0 4.3 29.5 20.4 12.2 6.9 16.6 14.7 12.3 28.1 9.4 3.8 5.0 3.9 20.3 23.6 1.4 7.6 46.3 71.8 81.2 0.4 7.4 4.8 2.1 24.0 25.7 3.9 3.9 20.7 12.0 30.4 0.4 15.5 3.0 10.6 32.6 4.7 9.7 34.3 11.7 11.5 4.1 27.1 22.9 20.6 1.8 20.2 15.0 6.5 20.1 13.3 1.1 7.0 5.5 16.2 0.0 8.0 14.8 13.0 0.7 3.5 12.9 1.3 42.2 0.9 1.2 12.9 14.8 6.0 3.0 9.6 1.6 24.1 7.2 1.2 16.8 6.0 12.1 16.4 12.8 18.2 23.3 11.7 31.1 13.0 19.5 25.4 10.2 10.1 16.3 17.7 16.4 32.7 20.3 2.0 21.7 15.5 27.1 27.4 26.3 30.1 27.2 28.5 27.3 27.0 27.2 28.8 29.5 28.1 23.3 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 5.4 21.7 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 6.7 6.8 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 2.6 3.3 0.0 0.0 0.0 SLC16A2 "AHDS, DXS128, MCT7, MCT8, MRX22, XPCT" ENSG00000147100 "Solute carrier family 16 member 2" P36021 X 74421493-74533917 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 40.7" "Cell type enhanced" "Detected in many" "Astrocytes: 22.2;Hepatocytes: 63.7;Inhibitory neurons: 21.6;Oligodendrocyte precursor cells: 23.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 83.9;GAMG: 70.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072719 Approved "Plasma membrane" NA NA "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "HPA072719: AB_2686552" "prognostic unfavorable (8.88e-5)" "unprognostic (2.48e-1)" "unprognostic (1.99e-1)" "unprognostic (2.90e-3)" "unprognostic (1.49e-1)" "unprognostic (1.58e-2)" "unprognostic (1.58e-3)" "unprognostic (2.47e-2)" "unprognostic (1.48e-1)" "unprognostic (2.54e-1)" "unprognostic (5.67e-2)" "unprognostic (3.51e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (2.15e-2)" "unprognostic (1.89e-1)" "unprognostic (6.89e-3)" "prognostic unfavorable (3.16e-4)" 13.8 24.7 4.6 4.8 5.8 0.0 5.4 1.7 5.7 9.4 1.2 7.0 3.3 10.3 1.7 2.9 9.3 6.0 10.4 7.7 4.9 7.9 40.7 7.5 0.9 5.6 3.9 12.8 5.5 11.7 9.8 9.2 1.8 6.2 1.8 1.1 5.0 5.8 2.7 2.5 3.1 6.9 3.5 1.2 4.7 0.9 8.1 5.7 12.6 3.7 1.8 6.6 6.2 3.0 8.4 10.4 7.2 43.1 20.8 11.1 0.0 83.9 29.7 38.2 20.6 0.1 0.9 0.0 1.3 37.5 70.8 1.7 1.1 40.2 22.1 6.1 3.6 0.0 0.0 0.0 1.5 0.0 0.0 16.5 9.5 19.3 23.3 14.6 0.1 0.1 0.0 0.0 9.1 0.0 0.5 2.7 27.2 0.0 7.8 17.4 19.9 0.0 18.0 0.1 1.9 12.0 9.6 50.2 0.3 2.5 0.6 1.1 0.0 32.5 8.8 35.7 41.9 0.0 0.0 0.0 34.7 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 5.8 1.7 5.7 7.7 4.9 5.6 3.9 1.8 3.5 8.1 3.0 5.6 0.0 0.6 22.2 0.2 0.8 4.3 2.4 0.6 5.7 4.3 3.4 4.5 8.6 2.9 3.7 0.0 5.7 0.1 0.0 3.9 4.3 0.1 0.3 9.8 6.1 8.4 0.0 14.5 2.4 4.9 11.8 0.5 0.5 2.5 1.7 3.6 63.7 1.0 3.3 21.6 0.3 0.0 1.3 0.8 1.2 15.2 0.1 3.6 15.9 0.6 6.2 0.0 23.1 7.1 4.6 0.0 20.7 0.1 5.1 0.4 4.7 2.4 1.5 13.1 9.7 5.6 0.1 0.1 0.9 1.3 2.1 0.4 1.4 0.2 4.9 SLC16A4 "MCT4, MCT5" ENSG00000168679 "Solute carrier family 16 member 4" O15374 1 110362851-110391082 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 124.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 71.7;Proximal tubular cells: 192.3" "Cancer enhanced" "Detected in all" "renal cancer: 35.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.5" "Lineage enriched" "Detected in single" 4 "B-cells: 1.5" "Cell line enhanced" "Detected in many" "BEWO: 20.4;BJ hTERT+: 20.7;CAPAN-2: 30.8;HHSteC: 19.2;hTERT-RPE1: 42.6;SK-MEL-30: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046986, HPA060163" Approved Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 43: B-cells - Humoral immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Microtubules, Cytosol" "Cytokinetic bridge" "HPA046986: AB_2679892, HPA060163: " "unprognostic (2.04e-1)" "unprognostic (1.69e-1)" "unprognostic (2.56e-1)" "unprognostic (2.77e-3)" "unprognostic (1.53e-1)" "unprognostic (2.22e-1)" "unprognostic (2.00e-2)" "unprognostic (7.94e-2)" "unprognostic (2.29e-1)" "unprognostic (1.81e-1)" "unprognostic (1.70e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.69e-4)" "unprognostic (3.68e-2)" "unprognostic (9.16e-2)" "unprognostic (1.71e-2)" "unprognostic (9.46e-2)" 4.9 2.9 2.7 4.6 3.1 1.0 6.9 5.8 4.4 4.2 15.4 3.6 9.5 3.0 22.4 2.7 4.0 13.7 4.6 3.5 4.1 124.1 16.3 9.2 3.4 4.1 3.1 21.4 0.9 0.4 3.8 28.6 3.9 3.8 1.6 2.3 3.6 5.8 1.3 1.3 11.4 3.4 4.1 2.7 2.7 5.2 3.0 0.6 8.5 3.9 1.1 7.9 3.5 4.2 0.4 9.8 2.3 2.7 6.3 12.9 20.4 5.3 20.7 1.8 5.3 3.1 30.8 0.6 5.7 17.1 0.1 0.5 0.1 1.9 1.9 0.5 2.5 0.5 2.7 3.3 19.2 0.9 0.5 10.0 0.3 3.0 0.2 42.6 4.1 0.8 0.5 1.2 3.3 1.0 0.4 0.6 0.9 0.0 0.3 0.2 1.3 0.1 3.7 0.4 1.2 0.9 0.6 9.8 30.6 9.0 0.7 0.1 0.4 1.4 0.7 0.3 1.5 0.5 0.1 1.6 1.1 0.4 6.1 0.0 0.2 0.1 0.1 0.0 0.0 1.5 0.1 0.0 0.0 0.3 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.1 2.7 3.1 5.8 4.4 3.5 4.1 4.1 3.1 3.9 4.1 3.0 4.2 1.9 12.8 20.8 2.3 5.8 3.1 6.1 11.2 1.2 11.5 14.7 6.5 1.1 11.5 6.8 71.7 6.2 39.5 5.8 0.9 3.9 2.7 0.5 3.3 6.8 4.6 3.5 2.7 8.2 0.9 34.6 18.2 1.5 3.3 5.1 5.2 4.2 5.0 4.2 3.3 7.1 0.9 4.1 1.6 3.0 2.2 18.0 1.8 10.6 15.0 1.8 2.4 9.2 2.5 4.7 1.9 1.2 11.7 1.2 3.1 38.4 192.3 3.5 20.1 0.0 4.5 5.4 3.4 1.9 0.5 3.7 35.2 3.9 7.0 1.4 7.2 SLC1A7 EAAT5 ENSG00000162383 "Solute carrier family 1 member 7" O00341 1 53087179-53142638 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "retina: 40.2" "Group enriched" "Detected in some" 6 "Bipolar cells: 207.7;Cone photoreceptor cells: 70.9;Rod photoreceptor cells: 72.3" "Cancer enhanced" "Detected in many" "lung cancer: 3.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.2" "Lineage enriched" "Detected in single" 22 "T-cells: 2.2" "Cell line enriched" "Detected in some" 8 "HHSteC: 21.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA049124 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 56: Bipolar cells - Visual perception" "HPA049124: AB_2680643" "unprognostic (2.33e-1)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (9.48e-4)" "unprognostic (2.31e-1)" "unprognostic (8.73e-2)" "unprognostic (1.52e-2)" "unprognostic (6.26e-3)" "unprognostic (4.35e-1)" "unprognostic (1.45e-2)" "unprognostic (1.59e-1)" "unprognostic (7.65e-2)" "unprognostic (1.19e-3)" "unprognostic (2.58e-3)" "unprognostic (5.43e-2)" "unprognostic (8.12e-2)" "unprognostic (4.70e-3)" 1.6 0.2 1.5 0.2 1.0 0.0 1.1 1.0 1.5 1.4 0.8 1.0 2.3 1.3 0.0 1.2 1.8 5.2 1.6 1.2 1.1 0.4 1.0 0.6 0.1 1.6 1.9 2.4 0.2 0.4 0.1 0.2 1.8 0.8 0.0 40.2 0.5 0.0 1.3 0.8 3.1 0.0 1.5 0.0 0.8 0.5 2.3 0.0 0.6 3.0 0.0 1.0 1.1 1.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.3 1.5 1.0 1.0 1.5 1.2 1.1 1.6 1.9 1.8 1.5 2.3 1.2 1.9 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 207.7 0.0 0.0 0.6 0.0 0.0 0.0 70.9 0.1 3.0 2.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.5 0.2 5.9 4.1 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 1.0 0.0 0.3 0.0 0.0 1.2 0.5 0.0 7.5 0.0 8.5 16.5 0.0 0.1 0.0 4.0 1.2 0.7 0.0 17.7 0.7 0.0 72.3 0.0 1.1 0.5 0.0 0.3 0.0 0.0 0.0 1.7 0.1 0.3 0.0 SLIT2 "SLIL3, Slit-2" ENSG00000145147 "Slit guidance ligand 2" O94813 4 20251905-20620561 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Excitatory neurons: 256.7;Inhibitory neurons: 544.9;Oligodendrocytes: 157.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 98.0;BJ hTERT+: 200.8;BJ hTERT+ SV40 Large T+: 97.8;fHDF/TERT166: 117.8;HBF TERT88: 112.0;HEK 293: 88.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007590, HPA019511, HPA023088" Uncertain "Secreted in other tissues" NA NA 77000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB007590: , HPA019511: AB_1857226, HPA023088: AB_1857227" "unprognostic (1.44e-1)" "unprognostic (4.54e-2)" "unprognostic (3.26e-2)" "unprognostic (6.13e-2)" "unprognostic (9.01e-3)" "unprognostic (6.49e-2)" "unprognostic (1.71e-1)" "unprognostic (4.78e-2)" "unprognostic (1.73e-1)" "unprognostic (6.16e-3)" "unprognostic (5.32e-2)" "unprognostic (4.30e-2)" "prognostic favorable (6.51e-4)" "unprognostic (4.93e-3)" "unprognostic (6.80e-3)" "unprognostic (1.74e-1)" "unprognostic (7.16e-4)" 8.0 24.9 3.2 3.3 6.4 0.0 9.4 0.0 14.0 24.0 11.7 11.5 2.4 16.4 9.9 5.8 13.1 9.4 7.8 6.6 20.5 12.3 2.0 34.9 1.8 7.9 3.1 4.3 2.8 1.5 8.8 25.2 4.5 12.6 5.4 13.2 6.1 15.7 2.9 3.8 4.8 24.9 0.4 14.2 9.0 1.3 17.6 2.4 9.2 5.1 1.2 13.1 13.9 2.4 0.1 0.0 54.6 0.0 37.8 34.8 1.7 98.0 200.8 97.8 36.9 0.4 0.1 0.0 3.4 117.8 0.2 1.2 15.7 7.9 112.0 0.2 88.3 0.0 0.4 0.0 7.2 0.9 0.0 8.5 0.0 63.6 18.6 2.1 35.0 0.0 0.0 0.0 4.6 0.0 0.0 0.4 1.7 0.0 6.3 61.2 0.5 0.0 1.0 0.1 3.5 0.8 0.0 0.2 0.4 1.9 0.2 0.2 2.0 34.9 5.0 35.0 54.2 0.0 0.1 0.0 0.9 0.0 19.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 6.4 0.0 14.0 6.6 20.5 7.9 3.1 4.5 0.4 17.6 2.4 1.6 0.0 9.0 10.1 0.0 8.0 2.0 0.1 0.6 47.6 1.0 0.6 5.2 1.5 1.3 0.0 0.0 1.1 0.0 0.6 1.9 1.7 0.6 6.4 1.9 2.0 1.2 0.0 256.7 0.5 1.2 58.8 0.0 7.1 2.5 1.3 4.2 0.2 1.9 0.0 544.9 0.0 0.0 1.0 9.7 1.7 26.4 0.7 8.8 31.9 0.0 1.3 0.0 43.7 157.9 0.2 0.0 26.7 0.1 3.7 0.0 11.5 7.4 2.1 6.6 3.2 6.4 0.2 1.7 1.2 6.7 2.1 1.1 20.3 0.1 1.9 SNCAIP SYPH1 ENSG00000064692 "Synuclein alpha interacting protein" Q9Y6H5 5 122311354-122464219 "Disease related genes, Predicted intracellular proteins" "Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 19.5;ovary: 37.5" "Cell type enhanced" "Detected in many" "Astrocytes: 84.5;Early spermatids: 68.1;Endometrial stromal cells: 56.9;Inhibitory neurons: 62.8;Oligodendrocyte precursor cells: 30.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 50 "basophil: 7.6" "Lineage enriched" "Detected in single" 50 "granulocytes: 7.6" "Cell line enhanced" "Detected in some" "AF22: 5.2;BJ hTERT+: 5.1;HBF TERT88: 3.2;OE19: 3.0;RPMI-8226: 5.2" "Low region specificity" "Detected in all" HPA064687 Uncertain Supported "Nucleoplasm,Cytoplasmic bodies" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Cytoplasmic bodies" Nucleoplasm "HPA064687: AB_2685324" "unprognostic (7.28e-3)" "unprognostic (1.02e-2)" "unprognostic (3.01e-1)" "unprognostic (6.56e-2)" "unprognostic (2.18e-2)" "unprognostic (1.56e-1)" "unprognostic (1.47e-2)" "unprognostic (4.95e-2)" "unprognostic (1.95e-2)" "unprognostic (3.73e-1)" "unprognostic (3.52e-2)" "unprognostic (3.00e-1)" "unprognostic (5.98e-2)" "unprognostic (1.82e-3)" "unprognostic (5.77e-2)" "unprognostic (2.82e-1)" "unprognostic (2.44e-1)" 3.1 1.0 2.5 2.5 7.8 0.3 1.4 7.2 3.0 17.2 10.1 1.1 1.2 19.5 1.3 0.6 5.1 2.5 1.3 2.9 2.9 1.7 0.1 1.2 2.1 4.6 5.2 37.5 0.5 0.2 1.2 2.0 4.2 1.9 1.1 0.5 0.4 2.7 0.3 1.8 0.7 12.0 3.0 5.2 1.0 4.5 5.7 1.7 0.8 1.6 1.5 4.1 2.5 4.3 0.0 0.0 5.2 0.1 0.0 0.0 0.1 2.2 5.1 0.8 0.4 0.0 0.1 0.1 0.1 2.2 0.4 0.0 2.1 0.3 3.2 1.9 0.4 0.0 0.3 0.0 0.0 0.0 0.1 0.4 0.0 0.3 0.2 0.0 0.6 0.1 0.0 0.8 0.0 0.0 0.0 0.1 2.5 3.0 0.0 0.1 0.0 5.2 0.2 0.6 0.9 0.0 0.0 0.0 0.0 1.6 0.4 0.0 0.0 0.2 0.5 0.3 0.4 0.0 0.0 0.2 0.2 0.0 0.1 7.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 2.5 7.8 7.2 3.0 2.9 2.9 4.6 5.2 4.2 3.0 5.7 4.3 6.1 0.0 0.5 84.5 0.0 1.8 3.8 0.5 1.8 0.4 0.4 1.0 0.8 1.5 1.7 0.0 0.0 0.0 0.0 0.0 0.0 6.1 68.1 4.6 56.9 7.1 0.0 0.0 21.8 0.0 0.1 5.6 0.0 1.4 1.3 0.1 18.9 0.2 0.3 0.0 62.8 0.0 0.0 0.8 0.4 16.6 5.3 0.6 1.8 13.1 0.0 0.5 0.0 30.7 1.9 0.4 0.7 5.7 0.0 3.0 0.0 0.3 14.9 0.0 0.0 0.5 2.3 4.1 2.1 1.8 2.7 0.1 0.4 0.1 0.2 1.5 SNTB1 "59-DAP, A1B, BSYN2, SNT2, SNT2B1, TIP-43" ENSG00000172164 "Syntrophin beta 1" Q13884 8 120535745-120813273 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 89.3" "Cell type enhanced" "Detected in many" "Astrocytes: 70.2;Hepatocytes: 66.8;Microglial cells: 45.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 84.9;OE19: 78.5;U-266/70: 77.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA024659 Uncertain "Intracellular and membrane" NA NA 25000 "Cluster 2: Granulocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA024659: AB_1857713" "unprognostic (1.32e-1)" "unprognostic (2.77e-2)" "unprognostic (6.12e-2)" "unprognostic (1.42e-1)" "unprognostic (6.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.76e-2)" "unprognostic (6.41e-3)" "unprognostic (2.07e-1)" "unprognostic (3.88e-1)" "unprognostic (1.31e-1)" "unprognostic (4.72e-1)" "unprognostic (2.00e-2)" "unprognostic (5.08e-2)" "unprognostic (5.88e-2)" "unprognostic (1.03e-1)" "unprognostic (1.71e-1)" 7.9 66.4 7.5 5.5 6.5 18.9 8.0 5.8 5.9 5.6 42.9 6.2 5.7 4.4 2.7 8.4 6.0 4.3 4.9 6.1 11.8 12.6 89.3 15.4 7.3 7.2 11.4 2.5 45.0 1.4 2.6 8.6 7.8 4.8 6.4 4.8 34.8 3.4 28.2 9.8 6.3 3.1 6.0 11.9 24.1 9.8 9.1 3.4 61.4 32.4 3.5 3.9 3.6 6.5 0.1 1.8 0.7 0.0 11.3 22.9 0.1 6.0 36.7 1.8 2.7 12.0 1.6 0.0 10.7 6.8 0.0 0.1 2.0 0.0 1.3 5.6 6.5 0.0 0.3 84.9 1.2 16.9 0.0 11.4 0.0 10.1 0.0 14.9 0.4 10.4 0.0 32.3 5.9 3.3 0.0 13.7 2.1 78.5 8.7 0.0 43.8 0.1 34.4 2.0 0.1 0.4 2.4 12.5 30.2 0.7 1.5 30.5 0.0 23.7 1.4 0.0 2.0 77.2 33.0 34.8 18.4 49.0 26.7 1.8 0.8 2.7 2.2 0.4 0.5 0.5 0.4 1.1 0.6 0.2 1.1 1.1 0.1 1.6 0.3 0.0 0.0 0.6 7.5 6.5 5.8 5.9 6.1 11.8 7.2 11.4 7.8 6.0 9.1 6.5 1.9 12.8 27.2 70.2 4.7 0.4 0.7 0.9 1.8 2.4 8.5 6.0 2.0 2.8 9.0 5.5 2.1 0.8 8.4 1.3 9.8 1.5 9.3 2.4 5.8 4.2 0.0 14.1 2.4 10.9 2.2 9.8 11.2 6.2 1.3 8.8 13.2 66.8 11.3 0.0 3.1 3.9 16.2 29.9 4.3 4.2 4.7 18.1 1.8 45.9 12.1 16.0 18.6 2.5 12.2 4.3 1.9 13.2 2.8 1.1 0.1 3.3 13.8 0.7 13.1 3.9 14.3 1.1 0.2 10.1 1.0 0.3 12.0 11.0 4.1 0.6 SOX8 ENSG00000005513 "SRY-box transcription factor 8" P57073 16 981770-986979 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 127.4" "Group enriched" "Detected in some" 9 "Muller glia cells: 156.1;Oligodendrocyte precursor cells: 64.3;Oligodendrocytes: 66.0" "Cancer enriched" "Detected in many" 6 "glioma: 46.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RH-30: 114.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041640, HPA058665" Enhanced Nucleoplasm No NA "Cluster 70: Brain - Nervous system development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA041640: AB_10964357, HPA058665: AB_2683792" "unprognostic (1.40e-2)" "unprognostic (2.56e-3)" "unprognostic (1.59e-1)" "unprognostic (3.10e-2)" "unprognostic (4.58e-2)" "unprognostic (7.16e-3)" "unprognostic (6.05e-3)" "unprognostic (3.01e-2)" "unprognostic (2.53e-1)" "unprognostic (1.16e-1)" "unprognostic (4.53e-3)" "unprognostic (4.46e-2)" "unprognostic (1.20e-3)" "unprognostic (8.50e-2)" "unprognostic (6.18e-2)" "unprognostic (5.47e-1)" "unprognostic (9.09e-2)" 0.9 0.5 58.3 0.9 90.4 0.1 1.7 66.7 71.8 1.3 23.6 3.1 0.1 0.4 0.1 0.4 0.6 0.5 4.1 54.0 57.9 0.7 0.2 0.3 2.0 73.6 79.8 0.3 1.0 0.1 1.2 0.4 64.9 1.2 0.6 14.8 8.3 0.4 0.8 5.4 1.8 0.2 58.7 1.0 0.9 2.5 71.2 0.4 0.5 0.6 2.3 1.4 1.6 127.4 0.0 0.6 2.2 21.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.3 0.0 0.0 0.4 5.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.0 0.0 0.0 3.3 1.8 0.2 0.0 114.7 4.5 0.0 0.0 0.0 0.0 0.1 0.0 4.1 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.3 0.4 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 58.3 90.4 66.7 71.8 54.0 57.9 73.6 79.8 64.9 58.7 71.2 127.4 1.5 0.0 0.0 10.1 0.2 0.4 0.5 0.0 0.0 1.8 8.7 10.4 1.2 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.5 0.0 0.0 0.6 2.6 0.0 0.0 4.6 0.2 0.1 1.9 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.3 0.5 3.4 0.3 1.8 3.7 0.6 156.1 0.0 64.3 66.0 0.1 0.3 1.9 0.5 1.9 0.0 0.0 0.0 8.0 0.0 9.9 0.9 0.0 3.9 0.4 1.0 0.0 0.9 0.1 0.9 0.3 STK32B "HSA250839, STK32, STKG6, YANK2" ENSG00000152953 "Serine/threonine kinase 32B" Q9NY57 4 5051480-5500994 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 15.0;lymphoid tissue: 19.5" "Cell type enhanced" "Detected in many" "Early spermatids: 108.2;Late spermatids: 39.3;Microglial cells: 27.2;Oligodendrocyte precursor cells: 169.4" "Cancer enhanced" "Detected in many" "renal cancer: 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 27.5;HUVEC TERT2: 27.5;REH: 25.2;U-2197: 43.8;WM-115: 112.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015820 Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 17: WM-115 - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nuclear bodies" Cytosol "HPA015820: AB_1858913" "unprognostic (4.48e-2)" "unprognostic (1.02e-1)" "unprognostic (6.08e-2)" "unprognostic (1.35e-1)" "unprognostic (8.12e-3)" "unprognostic (9.96e-2)" "unprognostic (1.64e-4)" "unprognostic (1.27e-1)" "unprognostic (1.27e-1)" "unprognostic (1.70e-1)" "unprognostic (2.54e-1)" "unprognostic (8.82e-2)" "prognostic favorable (1.63e-8)" "unprognostic (8.10e-3)" "unprognostic (5.04e-2)" "unprognostic (3.62e-2)" "unprognostic (1.67e-3)" 3.5 0.3 2.3 1.2 7.8 1.5 4.3 1.9 2.3 3.3 1.5 1.1 0.5 3.5 0.3 1.2 1.3 1.4 0.4 2.1 4.5 15.0 0.1 0.9 1.8 3.7 3.9 0.6 1.8 0.3 0.4 3.2 3.7 0.6 1.1 0.8 1.0 0.9 1.3 2.4 1.1 2.5 3.6 0.2 6.0 4.5 3.5 19.5 1.7 1.7 1.0 3.1 1.5 3.6 0.0 14.0 0.8 0.0 0.6 1.0 0.0 9.7 1.1 6.3 0.2 0.1 0.0 0.0 2.1 19.7 27.5 0.1 1.5 0.0 2.3 0.0 0.0 0.1 6.4 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.2 0.2 27.5 1.4 0.0 0.1 3.4 0.0 0.0 2.0 4.1 0.0 0.0 25.2 0.1 0.0 6.2 0.0 0.4 0.0 0.0 0.1 8.5 0.6 0.0 0.0 7.1 0.2 2.8 43.8 0.0 0.9 0.1 0.0 0.1 0.0 112.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.3 7.8 1.9 2.3 2.1 4.5 3.7 3.9 3.7 3.6 3.5 3.6 3.6 0.0 1.1 1.6 0.0 2.3 0.2 0.0 0.0 0.0 4.2 1.7 0.4 0.0 0.0 0.0 0.0 0.0 1.5 0.0 17.6 1.1 108.2 0.2 0.1 3.2 0.0 0.0 3.7 0.0 0.1 5.5 4.1 0.3 0.0 0.0 0.0 0.0 1.7 0.0 14.4 0.0 0.0 0.0 1.2 39.3 1.5 1.1 5.4 27.2 0.5 0.0 0.0 169.4 1.3 0.4 0.0 1.2 0.0 0.1 0.0 18.9 0.0 0.0 0.0 0.6 0.4 1.2 5.5 0.0 1.0 0.0 0.2 0.4 0.0 0.1 SYT17 Syt-17 ENSG00000103528 "Synaptotagmin 17" Q9BSW7 16 19167971-19268332 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.6;parathyroid gland: 25.3" "Cell type enhanced" "Detected in many" "Astrocytes: 90.8;Microglial cells: 51.5;Oligodendrocyte precursor cells: 114.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 6.2;memory B-cell: 7.8;naive B-cell: 19.0;non-classical monocyte: 20.1" "Group enriched" "Detected in many" 9 "B-cells: 19.0;monocytes: 20.1" "Cell line enhanced" "Detected in many" "BEWO: 14.2;CAPAN-2: 28.1;Daudi: 12.6;MCF7: 21.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042059 Approved Nucleoplasm,Cytosol NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Cytosol" "HPA042059: AB_2677827" "unprognostic (3.43e-1)" "unprognostic (2.75e-1)" "unprognostic (2.29e-2)" "unprognostic (1.49e-2)" "unprognostic (2.74e-1)" "unprognostic (1.11e-2)" "unprognostic (9.31e-2)" "unprognostic (2.43e-1)" "unprognostic (6.76e-2)" "unprognostic (1.97e-1)" "unprognostic (3.15e-1)" "unprognostic (6.59e-2)" "unprognostic (3.00e-3)" "unprognostic (4.53e-2)" "unprognostic (3.38e-1)" "unprognostic (7.32e-2)" "unprognostic (4.95e-3)" 4.8 4.8 20.8 1.4 25.7 0.3 4.3 13.4 24.4 3.1 20.2 2.6 4.2 1.0 2.7 4.4 2.2 1.0 1.7 25.8 23.3 5.9 17.4 7.8 3.3 17.8 28.6 0.6 3.0 25.3 18.8 3.8 17.7 9.2 2.8 1.7 1.6 3.3 0.3 10.0 1.9 0.8 15.8 1.3 5.9 0.4 28.2 0.6 6.8 0.6 4.7 3.4 2.6 16.0 0.1 10.4 0.1 0.1 0.3 0.7 14.2 0.0 0.0 0.1 0.0 0.4 28.1 12.6 3.4 0.0 3.8 5.0 0.7 0.4 0.0 0.0 2.1 0.0 10.9 0.2 0.0 0.0 0.1 0.9 2.5 0.1 0.0 0.2 0.5 0.0 0.0 0.0 0.0 21.8 0.0 0.1 1.2 8.3 5.7 0.0 1.2 1.0 3.5 6.2 2.1 1.2 4.0 11.0 0.5 6.7 10.9 2.8 0.0 0.0 7.1 0.1 0.0 2.0 0.0 11.4 0.0 0.1 0.0 0.4 0.7 0.0 0.0 6.2 0.0 7.8 0.0 0.0 2.2 19.0 0.0 0.0 0.1 0.0 20.1 0.2 0.0 0.9 20.8 25.7 13.4 24.4 25.8 23.3 17.8 28.6 17.7 15.8 28.2 16.0 0.7 6.4 9.3 90.8 8.6 3.8 12.0 3.8 7.4 1.8 7.6 4.1 1.6 2.8 7.5 22.0 0.0 6.4 0.0 4.3 27.4 4.9 0.2 2.3 0.6 2.9 21.6 5.3 18.6 0.6 15.3 2.3 2.0 2.5 0.0 0.1 3.9 23.2 4.0 1.7 20.9 10.0 34.6 4.0 4.0 0.1 1.5 3.6 12.4 51.5 6.2 12.0 0.0 114.1 1.7 3.6 9.0 0.7 0.0 6.0 0.4 0.6 5.8 0.5 0.0 6.7 1.6 0.3 3.9 3.6 9.7 4.0 0.2 0.1 4.3 8.2 SYTL2 "CHR11SYT, exophilin-4, FLJ20163, FLJ21219, KIAA1597, MGC102768, PPP1R151, SGA72M, SLP2" ENSG00000137501 "Synaptotagmin like 2" Q9HCH5 11 85694224-85811159 "Plasma proteins, Predicted intracellular proteins, Transporters" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 74.2;stomach 1: 127.7" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 382.2;granulocytes: 130.8;Intestinal goblet cells: 185.9;Respiratory ciliated cells: 138.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 14.0;MAIT T-cell: 23.7" "Lineage enriched" "Detected in many" 5 "T-cells: 23.7" "Cell line enhanced" "Detected in many" "MCF7: 91.1;OE19: 148.1;RH-30: 175.8;RPTEC TERT1: 124.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039651 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Golgi apparatus" "Plasma membrane" "HPA039651: AB_10795153" "unprognostic (8.07e-3)" "unprognostic (6.72e-3)" "prognostic favorable (2.67e-4)" "unprognostic (9.34e-4)" "unprognostic (6.60e-3)" "unprognostic (2.19e-4)" "unprognostic (2.24e-2)" "unprognostic (5.37e-2)" "unprognostic (5.56e-2)" "unprognostic (5.45e-2)" "unprognostic (1.92e-2)" "unprognostic (2.97e-2)" "unprognostic (2.85e-2)" "unprognostic (4.03e-1)" "unprognostic (1.87e-2)" "unprognostic (9.72e-2)" "prognostic favorable (9.07e-4)" 16.7 9.6 19.3 12.9 24.6 3.3 16.0 8.7 35.7 10.7 11.9 51.7 21.6 9.1 16.3 17.0 7.6 27.8 8.4 29.0 25.1 20.2 6.9 14.8 11.1 26.4 14.0 4.8 2.7 6.4 6.1 18.2 17.9 13.6 74.2 13.3 8.9 9.8 5.1 6.8 25.0 10.2 15.6 10.4 127.7 5.1 13.8 7.1 4.7 2.7 6.8 50.9 7.4 29.1 3.5 8.0 12.2 1.0 2.8 15.4 0.2 30.3 39.4 26.3 59.2 34.7 4.5 0.7 11.1 21.3 38.0 22.3 0.8 2.7 34.5 2.4 0.2 0.0 0.2 0.3 1.8 2.7 0.5 19.6 3.8 56.8 0.8 6.2 0.2 1.0 0.4 0.4 33.6 91.1 0.1 0.9 20.6 148.1 13.6 1.3 175.8 0.1 124.2 46.8 0.3 0.6 6.7 5.4 3.0 10.2 0.6 0.5 0.1 40.8 15.6 25.9 1.5 0.2 0.0 16.1 41.9 0.5 25.7 0.0 0.0 0.0 14.0 0.0 23.7 0.0 2.8 8.4 0.0 0.1 2.3 4.1 0.0 4.6 0.1 1.0 1.1 2.6 19.3 24.6 8.7 35.7 29.0 25.1 26.4 14.0 17.9 15.6 13.8 29.1 7.5 22.4 32.5 15.3 3.0 3.6 11.7 15.8 1.8 10.4 45.4 14.0 2.3 8.6 62.1 68.0 8.4 0.7 45.6 115.2 0.0 9.1 1.2 8.0 2.2 6.4 19.2 4.0 103.9 16.9 0.4 11.5 382.2 2.3 130.8 0.8 5.0 0.5 0.5 1.7 23.2 185.9 2.0 5.9 5.0 0.9 1.8 4.6 10.6 20.6 1.6 14.0 63.8 35.7 91.9 16.5 40.6 30.1 31.6 30.7 16.3 8.6 138.4 8.1 32.9 42.1 59.8 3.6 2.6 2.2 5.7 0.4 50.1 2.3 36.7 60.9 TBX15 TBX14 ENSG00000092607 "T-box transcription factor 15" Q96SF7 1 118883046-118989556 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 46.8;skeletal muscle: 132.2;tongue: 114.7" "Cell type enhanced" "Detected in some" "Early spermatids: 8.2;Fibroblasts: 11.1;Hepatocytes: 15.3;Melanocytes: 7.2;Skeletal myocytes: 13.1;Smooth muscle cells: 12.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 52.6;ASC TERT1: 22.1;BJ hTERT+ SV40 Large T+ RasG12V: 20.4;fHDF/TERT166: 28.2;HSkMC: 37.9;RH-30: 29.1;U-2197: 27.3" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "spinal cord: 3.3" "HPA052245, HPA053713" Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Centrosome "HPA052245: AB_2681771, HPA053713: " "unprognostic (1.94e-1)" "unprognostic (2.75e-3)" "unprognostic (1.92e-2)" "unprognostic (3.94e-2)" "unprognostic (5.72e-3)" "unprognostic (7.79e-2)" "unprognostic (5.82e-2)" "unprognostic (2.46e-1)" "unprognostic (3.00e-3)" "unprognostic (1.39e-1)" "unprognostic (3.81e-3)" "unprognostic (5.03e-2)" "prognostic unfavorable (5.57e-8)" "unprognostic (2.63e-2)" "unprognostic (3.90e-2)" "unprognostic (1.88e-3)" "unprognostic (2.31e-1)" 29.8 0.1 0.8 0.0 1.0 0.0 16.1 0.7 1.3 0.1 2.1 0.1 0.0 0.2 0.1 1.9 0.4 0.5 3.1 0.7 0.6 1.0 46.8 0.6 2.7 0.6 0.7 0.1 0.1 0.5 1.5 0.1 0.7 1.4 0.0 0.2 6.9 0.0 132.2 9.4 0.1 0.1 0.5 0.0 0.1 0.7 0.9 0.3 1.9 114.7 1.3 0.4 0.3 0.7 1.4 0.0 0.0 0.0 52.6 22.1 0.0 4.7 6.4 12.3 20.4 0.0 0.0 0.0 2.6 28.2 0.0 0.0 0.0 0.0 4.9 0.0 0.3 0.0 1.4 0.0 0.1 0.4 0.0 37.9 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.2 14.1 0.0 0.0 0.2 2.3 0.0 0.2 0.0 29.1 0.4 3.0 1.4 0.6 0.0 1.6 0.0 0.6 0.6 0.0 0.6 0.0 6.6 4.0 27.3 0.2 0.4 0.2 0.0 13.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.0 0.7 1.3 0.7 0.6 0.6 0.7 0.7 0.5 0.9 0.7 3.2 0.0 0.0 0.3 0.0 2.0 0.0 0.0 0.0 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 8.2 0.1 0.0 1.2 0.0 0.0 0.3 0.0 0.0 11.1 0.0 0.1 0.0 0.0 0.0 15.3 0.1 0.0 0.2 0.0 0.0 0.0 4.0 1.1 0.0 0.1 7.2 1.9 0.0 0.0 0.0 0.5 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.1 12.5 0.2 0.4 0.0 2.0 0.0 0.3 0.1 0.0 0.0 TCEAL5 WEX4 ENSG00000204065 "Transcription elongation factor A like 5" Q5H9L2 X 103273691-103276750 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 67.3;choroid plexus: 35.5;pituitary gland: 62.2;retina: 23.5;testis: 60.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 43.4;Granulosa cells: 16.5;Late spermatids: 22.1;Muller glia cells: 75.5;Peritubular cells: 35.7" "Cancer enhanced" "Detected in many" "glioma: 13.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "SCLC-21H: 9.0;SH-SY5Y: 28.0" "Low region specificity" "Detected in all" "HPA045564, HPA058982" Supported Approved Nucleoplasm NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA045564: AB_2679369, HPA058982: AB_2683870" "unprognostic (1.30e-3)" "unprognostic (2.41e-1)" "prognostic unfavorable (9.09e-4)" "unprognostic (9.68e-2)" "unprognostic (8.75e-4)" "unprognostic (1.21e-1)" "unprognostic (8.11e-2)" "prognostic favorable (8.60e-4)" "unprognostic (1.28e-2)" "unprognostic (1.96e-2)" "unprognostic (1.08e-3)" "unprognostic (1.74e-1)" "unprognostic (6.30e-2)" "unprognostic (6.03e-4)" 0.9 10.5 56.5 0.9 54.9 0.0 2.1 55.4 67.3 6.2 35.5 2.2 0.6 5.6 6.8 0.3 2.4 0.8 2.7 52.9 55.2 0.3 0.1 0.3 0.0 50.8 52.6 5.2 0.9 0.0 62.2 0.0 49.5 3.3 0.7 23.5 1.1 4.1 0.1 0.4 1.2 3.3 44.9 0.0 1.0 60.0 50.3 0.6 2.3 0.7 0.0 1.5 3.8 55.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 28.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 56.5 54.9 55.4 67.3 52.9 55.2 50.8 52.6 49.5 44.9 50.3 55.4 0.1 0.0 0.0 2.9 0.0 0.1 0.5 0.0 1.8 43.4 0.3 9.5 2.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.4 0.3 7.5 0.6 0.0 0.0 7.0 0.0 0.4 7.6 0.0 0.2 0.0 16.5 0.0 0.0 0.3 1.7 7.7 0.0 0.0 0.0 1.7 22.1 8.4 0.7 0.0 2.8 0.0 75.5 0.0 7.1 2.8 0.0 0.0 35.7 0.0 0.2 0.0 0.3 0.0 6.8 0.0 6.9 1.4 7.6 1.9 0.1 0.3 0.4 0.1 0.2 0.0 0.2 TCEAL7 "MGC23947, WEX5" ENSG00000182916 "Transcription elongation factor A like 7" Q9BRU2 X 103330229-103332326 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 126.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.9;Fibroblasts: 55.2;Horizontal cells: 48.8;Leydig cells: 43.8;Muller glia cells: 88.3;Oligodendrocytes: 46.5;Peritubular cells: 39.1;Skeletal myocytes: 48.3;Smooth muscle cells: 38.7" "Cancer enriched" "Detected in many" 10 "glioma: 39.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 83.8;BJ hTERT+ SV40 Large T+ RasG12V: 75.1;GAMG: 115.3;hTEC/SVTERT24-B: 83.8;LHCN-M2: 72.0;SCLC-21H: 210.1;U-87 MG: 78.9" "Low region specificity" "Detected in many" "HPA051507, HPA065080" Enhanced Supported Nucleoplasm NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "HPA051507: AB_2681512, HPA065080: AB_2685419" "unprognostic (1.09e-2)" "unprognostic (4.36e-2)" "unprognostic (5.54e-2)" "unprognostic (2.26e-1)" "unprognostic (1.17e-1)" "unprognostic (4.52e-2)" "unprognostic (2.17e-1)" "unprognostic (2.23e-1)" "unprognostic (3.26e-2)" "unprognostic (1.12e-1)" "unprognostic (4.18e-1)" "unprognostic (1.12e-2)" "prognostic unfavorable (4.31e-4)" "prognostic unfavorable (3.53e-4)" "unprognostic (2.62e-1)" "unprognostic (2.28e-2)" "unprognostic (1.35e-3)" 7.7 27.9 72.4 4.3 73.0 0.0 9.1 75.1 126.3 26.3 40.5 18.6 4.0 48.2 18.3 5.5 17.0 11.9 14.0 72.1 84.5 5.0 2.4 6.1 2.3 80.8 77.5 29.0 1.2 1.1 37.4 2.1 82.3 12.3 7.8 23.5 3.5 13.2 3.7 1.8 8.3 29.9 74.5 5.8 6.5 3.1 77.2 5.1 3.8 9.9 1.4 9.7 15.6 96.0 0.0 0.0 83.8 0.0 36.3 55.5 15.0 12.0 61.9 26.4 75.1 0.0 0.0 0.0 0.0 12.9 115.3 0.0 0.0 1.8 45.5 0.0 0.8 0.3 0.0 0.0 18.2 0.0 0.1 46.6 0.0 83.8 0.1 0.0 27.6 0.0 0.5 0.2 72.0 0.0 0.1 0.3 0.3 0.1 0.0 0.0 53.1 0.3 0.0 0.0 210.1 56.6 0.0 0.4 0.0 0.4 0.0 0.0 0.0 38.8 1.4 0.6 0.0 0.0 0.0 0.0 78.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 72.4 73.0 75.1 126.3 72.1 84.5 80.8 77.5 82.3 74.5 77.2 96.0 4.8 0.0 1.3 5.9 0.0 2.5 5.3 0.3 1.2 36.4 0.9 19.2 13.6 0.0 0.7 3.7 4.2 1.4 0.1 0.0 5.9 0.2 0.2 1.0 42.9 5.2 0.0 0.0 21.2 0.0 0.7 55.2 0.0 0.7 0.0 19.2 1.8 0.0 0.7 48.8 26.5 0.0 0.0 0.0 4.0 1.8 43.8 0.6 8.8 4.7 0.0 88.3 0.0 19.6 46.5 0.3 0.0 39.1 0.1 1.1 0.0 2.1 0.0 12.9 13.1 48.3 38.7 3.0 1.5 0.8 3.1 0.3 0.5 5.1 0.0 0.8 TCF7L1 TCF3 ENSG00000152284 "Transcription factor 7 like 1" Q9HCS4 2 85133392-85310387 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 49.2;Astrocytes: 76.4;Leydig cells: 65.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 43.3;NTERA-2: 99.0;RH-30: 44.7;T-47d: 44.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071298 Supported Nucleoplasm,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA071298: AB_2686383" "unprognostic (1.59e-1)" "unprognostic (1.86e-1)" "unprognostic (3.64e-3)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.05e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (6.16e-5)" "unprognostic (1.79e-2)" "unprognostic (3.59e-3)" "unprognostic (2.73e-1)" "unprognostic (5.17e-3)" "unprognostic (1.69e-1)" "prognostic unfavorable (2.06e-4)" "prognostic unfavorable (2.72e-4)" "unprognostic (1.70e-1)" "unprognostic (3.52e-2)" "prognostic unfavorable (5.38e-4)" 37.8 5.3 7.5 4.0 9.9 3.7 33.4 7.8 6.4 33.1 13.8 27.6 4.3 25.9 6.7 10.0 20.1 7.2 20.3 6.9 7.7 15.7 12.5 17.8 5.9 10.8 13.0 27.5 4.5 7.0 8.9 5.2 6.9 20.0 4.1 1.7 13.1 14.5 15.0 14.6 12.2 13.0 7.4 11.8 10.7 9.1 10.0 5.8 30.6 7.9 3.5 18.3 24.1 6.7 2.1 1.5 33.5 25.8 12.6 2.6 20.3 2.5 8.5 5.8 5.3 5.2 2.0 0.7 4.0 5.6 6.4 4.7 25.9 43.3 4.0 1.8 4.1 0.7 2.1 2.3 1.2 0.3 4.9 2.1 7.7 0.6 1.4 2.6 11.2 1.3 0.5 1.3 6.8 1.6 0.2 1.6 99.0 1.3 0.9 0.6 44.7 0.5 2.7 3.7 1.0 10.4 4.0 17.1 1.3 25.9 44.3 0.9 12.1 6.5 9.2 0.4 3.3 1.1 0.3 0.4 0.2 1.0 5.2 5.1 0.5 1.1 0.5 0.4 0.7 1.1 0.6 0.7 0.2 1.5 0.7 0.9 1.3 0.9 0.5 0.9 0.6 0.1 7.5 9.9 7.8 6.4 6.9 7.7 10.8 13.0 6.9 7.4 10.0 6.7 49.2 6.4 37.3 76.4 1.0 6.0 14.4 12.9 15.9 0.2 20.0 33.1 9.1 5.7 10.5 16.5 0.0 6.3 0.8 0.3 0.0 3.7 28.2 9.4 17.5 31.4 0.0 0.0 1.1 5.6 4.0 28.9 0.5 16.0 5.1 39.4 45.7 6.7 1.7 0.0 2.2 2.9 8.2 9.1 8.3 5.4 65.3 2.2 3.6 22.5 1.0 4.9 0.0 32.2 1.5 1.1 1.6 28.6 1.4 10.8 5.0 2.2 7.7 0.2 6.6 24.9 28.9 1.9 9.3 3.4 3.4 1.4 1.2 2.9 2.1 2.4 TEDC1 C14orf80 ENSG00000185347 "Tubulin epsilon and delta complex 1" Q86SX3 14 105489855-105499575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 11.6;Endometrial ciliated cells: 12.0;Exocrine glandular cells: 12.7;Extravillous trophoblasts: 26.6;Hofbauer cells: 14.6;monocytes: 11.9;Pancreatic endocrine cells: 14.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 66.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA039049, HPA039050" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Intracellular and membrane" No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 6: Brain - Smell perception" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA039049: AB_2676320, HPA039050: AB_10670918" "unprognostic (8.06e-2)" "unprognostic (1.06e-2)" "unprognostic (9.17e-2)" "unprognostic (1.65e-1)" "unprognostic (3.06e-1)" "unprognostic (1.57e-2)" "prognostic unfavorable (3.54e-4)" "unprognostic (5.19e-2)" "unprognostic (1.49e-1)" "unprognostic (3.12e-1)" "unprognostic (3.81e-2)" "unprognostic (2.91e-2)" "unprognostic (1.12e-3)" "unprognostic (8.73e-3)" "unprognostic (2.88e-1)" "unprognostic (1.17e-1)" "unprognostic (6.18e-3)" 5.1 1.6 5.2 4.9 5.5 6.8 4.7 4.1 7.8 4.3 0.5 5.5 5.1 3.8 1.0 6.8 4.6 1.8 4.3 5.8 3.0 4.0 5.4 4.9 5.4 7.0 3.5 2.5 3.0 1.0 5.3 1.6 4.2 4.2 1.6 0.5 4.3 2.3 2.3 8.2 5.4 1.0 3.1 6.8 5.9 4.9 3.6 4.5 5.7 0.5 3.1 3.9 4.5 5.3 17.2 38.9 9.2 13.5 0.8 1.5 24.5 13.4 5.0 15.9 14.7 14.0 31.2 25.6 27.2 2.2 6.2 43.5 3.2 14.0 3.0 29.0 16.0 6.5 22.8 13.3 0.6 12.9 17.9 0.3 4.6 10.6 3.5 2.0 6.4 23.2 10.5 31.2 2.5 66.7 26.9 29.6 11.9 14.6 41.8 21.9 13.8 17.9 4.5 14.3 25.7 15.5 13.7 15.8 9.8 2.0 26.0 12.6 7.8 10.9 18.4 33.4 22.4 17.8 8.2 15.7 13.9 14.8 18.0 0.0 0.5 0.6 0.5 0.9 0.4 0.1 0.8 1.4 0.7 0.3 0.6 0.1 0.1 0.0 0.8 2.4 0.6 0.2 5.2 5.5 4.1 7.8 5.8 3.0 7.0 3.5 4.2 3.1 3.6 5.3 4.8 3.2 2.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 5.9 5.3 0.0 0.0 0.6 1.8 0.0 8.0 10.1 0.0 3.9 11.6 0.0 12.0 3.0 4.0 0.0 0.0 0.0 12.7 26.6 3.4 0.0 7.2 0.0 8.1 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 11.9 0.0 0.0 0.0 0.0 14.7 0.0 0.0 4.7 0.0 0.0 2.0 3.6 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 4.0 4.2 2.5 0.0 0.0 TENM1 "ODZ1, ODZ3, TEN-M1, TEN1, TNM" ENSG00000009694 "Teneurin transmembrane protein 1" Q9UKZ4 X 124375903-124963817 "Predicted membrane proteins, Transporters" "Stress response, Transcription, Transcription regulation" "Neuropeptide, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.1" "Group enriched" "Detected in many" 11 "Excitatory neurons: 126.0;Inhibitory neurons: 463.2;Oligodendrocyte precursor cells: 434.8" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.0" "Region enhanced" "Detected in all" "cerebellum: 23.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 2.2;MOLT-4: 5.9;RPTEC TERT1: 2.0;SCLC-21H: 1.9;U-138 MG: 3.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002848 Uncertain NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA002848: AB_1079523" "unprognostic (1.71e-3)" "unprognostic (8.25e-2)" "unprognostic (3.14e-1)" "unprognostic (8.68e-4)" "unprognostic (5.76e-3)" "unprognostic (3.51e-2)" "unprognostic (7.07e-2)" "unprognostic (2.68e-4)" "unprognostic (6.58e-2)" "unprognostic (1.71e-1)" "unprognostic (4.49e-3)" "unprognostic (3.58e-1)" "unprognostic (2.71e-2)" "unprognostic (4.41e-2)" "unprognostic (1.99e-1)" "unprognostic (3.25e-3)" "unprognostic (4.44e-2)" 2.6 1.6 4.8 0.2 4.9 2.1 1.1 23.1 3.7 0.2 0.0 1.8 0.1 1.9 1.2 0.2 1.7 0.7 0.4 4.4 5.8 1.3 8.0 1.4 0.6 2.2 3.6 0.1 0.1 0.1 4.7 0.0 4.0 4.6 0.2 2.5 1.4 0.9 1.0 1.3 1.2 0.6 2.3 0.6 0.8 0.4 4.2 8.1 1.7 0.8 0.4 0.5 0.3 1.9 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 1.3 0.0 0.6 0.0 0.0 5.9 0.0 0.3 0.0 0.8 0.0 0.0 0.0 2.0 0.0 1.9 0.0 0.0 0.4 0.0 1.2 0.4 0.0 0.0 3.2 0.1 0.0 0.2 0.2 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.3 0.2 0.5 0.1 0.0 0.0 0.0 0.0 4.8 4.9 23.1 3.7 4.4 5.8 2.2 3.6 4.0 2.3 4.2 1.9 0.7 0.0 0.0 29.0 0.2 3.3 0.1 0.0 1.8 10.2 0.6 0.3 1.6 1.5 0.0 1.8 0.0 0.0 3.4 0.1 0.0 0.0 1.2 0.2 0.0 0.9 0.0 2.7 126.0 0.0 0.0 6.8 0.0 0.2 7.6 2.2 0.4 22.9 0.0 6.7 463.2 0.0 0.0 1.0 0.8 0.4 5.0 0.3 3.6 5.6 0.6 0.7 2.1 434.8 7.7 0.0 0.0 0.0 3.0 13.7 0.0 4.0 0.0 0.6 0.0 0.6 1.8 0.0 3.4 0.1 1.8 0.0 2.2 0.0 0.0 0.3 TENM4 "KIAA1302, ODZ4, Ten-M4, TEN4" ENSG00000149256 "Teneurin transmembrane protein 4" Q6N022 11 78652829-79441030 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.8;ovary: 16.6;parathyroid gland: 14.0" "Cell type enhanced" "Detected in many" "Astrocytes: 134.5;Early spermatids: 96.8;Excitatory neurons: 337.4;Inhibitory neurons: 297.7;Microglial cells: 117.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 9.1;hTERT-RPE1: 9.5;PC-3: 10.8;REH: 10.4;SH-SY5Y: 17.4" "Low region specificity" "Detected in all" "HPA019521, HPA065961" Approved NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA019521: AB_2670171, HPA065961: AB_2685588" "unprognostic (2.81e-1)" "unprognostic (9.25e-2)" "unprognostic (1.64e-1)" "unprognostic (2.96e-3)" "unprognostic (1.87e-1)" "unprognostic (2.48e-1)" "unprognostic (1.18e-2)" "unprognostic (1.24e-1)" "unprognostic (3.01e-1)" "unprognostic (3.79e-1)" "unprognostic (1.01e-1)" "unprognostic (4.71e-1)" "unprognostic (6.51e-3)" "unprognostic (5.40e-3)" "unprognostic (5.64e-2)" "unprognostic (7.07e-2)" "unprognostic (9.81e-3)" 1.9 1.4 7.5 1.0 13.4 0.0 0.7 0.3 12.6 2.5 0.0 0.5 0.1 1.3 0.2 2.0 2.1 0.4 0.4 9.0 7.5 1.5 0.0 0.4 0.5 10.9 9.2 16.6 0.3 14.0 7.1 0.1 7.9 0.4 0.3 2.6 0.5 0.2 0.4 3.3 0.3 1.0 13.0 0.3 0.5 1.6 11.8 1.9 5.8 1.0 1.2 0.5 1.5 17.8 0.0 0.0 3.4 0.0 3.7 5.9 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 7.8 6.7 0.0 2.1 5.0 5.3 0.0 4.5 0.9 0.0 0.0 0.0 0.1 0.0 0.0 9.1 2.3 2.5 4.5 9.5 0.0 0.0 0.1 0.3 0.2 0.0 0.1 0.0 1.8 0.3 10.8 10.4 0.0 0.0 6.4 1.1 7.1 17.4 0.0 0.0 0.0 6.2 0.0 0.1 0.5 0.1 1.2 0.1 5.9 0.0 0.0 0.1 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 13.4 0.3 12.6 9.0 7.5 10.9 9.2 7.9 13.0 11.8 17.8 0.1 0.0 0.0 134.5 0.2 0.9 0.8 3.4 17.1 7.5 0.1 0.0 1.9 4.3 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 96.8 1.1 1.7 0.3 0.0 0.0 337.4 0.0 0.2 2.6 0.0 0.8 1.3 0.8 0.0 0.0 0.1 0.0 297.7 0.0 0.0 0.6 0.4 56.6 5.3 0.7 0.0 117.1 0.4 13.9 0.0 58.3 21.3 0.0 0.0 1.9 0.0 0.4 0.0 0.4 7.0 1.0 0.0 25.1 2.8 4.8 1.0 7.3 2.0 0.1 0.1 0.3 0.0 0.6 TGFB3 "ARVD, ARVD1" ENSG00000119699 "Transforming growth factor beta 3" P10600 14 75958097-75983011 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor, Mitogen" "Cancer-related genes, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 28.8;Late spermatids: 48.9;Leydig cells: 27.1;Sertoli cells: 32.9;Smooth muscle cells: 24.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "SK-BR-3: 104.6;T-47d: 75.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA063582 Approved Vesicles "Secreted to blood" NA NA 44800 "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA063582: AB_2685049" "unprognostic (7.84e-2)" "unprognostic (1.89e-1)" "unprognostic (4.32e-3)" "unprognostic (1.29e-1)" "unprognostic (3.27e-2)" "unprognostic (1.58e-1)" "unprognostic (1.24e-1)" "unprognostic (9.79e-2)" "unprognostic (2.83e-2)" "unprognostic (1.51e-2)" "unprognostic (5.63e-2)" "unprognostic (4.10e-1)" "prognostic unfavorable (4.01e-7)" "unprognostic (6.38e-3)" "unprognostic (1.10e-1)" "unprognostic (1.22e-2)" "unprognostic (3.27e-3)" 22.2 13.0 43.4 15.8 45.8 1.0 15.6 33.5 58.4 46.6 18.4 12.8 4.1 25.5 9.6 7.7 14.5 36.6 27.9 31.2 38.4 20.5 17.6 25.7 7.2 40.9 42.3 8.0 27.7 9.9 8.3 55.4 40.0 43.6 4.8 1.8 10.8 17.9 38.6 5.0 6.6 34.3 38.9 5.3 14.1 4.5 42.2 6.5 12.3 11.0 8.8 45.8 16.2 70.1 1.1 1.5 1.1 13.4 2.1 4.3 0.4 1.0 1.5 0.7 0.7 0.8 3.4 0.1 1.0 2.8 0.4 0.9 2.9 0.7 0.3 0.8 1.5 0.1 3.5 1.5 2.7 0.6 0.9 10.2 0.4 1.0 0.4 2.3 3.2 2.7 1.5 6.3 0.8 7.0 0.8 0.8 0.4 0.8 5.3 3.3 4.2 0.7 1.2 0.6 21.9 6.3 4.3 104.6 0.8 1.5 75.2 0.5 0.8 2.0 4.5 2.1 5.8 0.8 1.3 0.4 3.6 1.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.4 45.8 33.5 58.4 31.2 38.4 40.9 42.3 40.0 38.9 42.2 70.1 8.6 0.0 2.8 5.5 0.8 4.5 1.2 2.1 1.2 0.7 15.1 6.1 3.6 0.0 3.3 1.8 4.2 0.5 1.2 1.3 0.0 0.5 16.4 2.6 9.9 10.2 0.0 0.0 1.3 1.3 0.4 28.8 0.0 2.4 0.0 0.5 7.9 0.8 0.9 0.0 3.0 2.6 6.1 0.6 4.4 48.9 27.1 0.9 10.6 1.0 0.7 2.1 3.1 5.5 4.7 0.4 0.1 12.8 0.5 20.6 1.4 0.4 4.2 3.9 32.9 13.9 24.4 0.4 1.4 2.4 3.1 1.4 1.3 1.6 0.4 0.8 TGFBI "BIGH3, CDB1, CDGG1, CSD1, CSD2, CSD3, LCD1" ENSG00000120708 "Transforming growth factor beta induced" Q15582 5 136028988-136063818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Sensory transduction, Vision" "Amyloidosis, Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 457.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 251.8;Kupffer cells: 292.9;Langerhans cells: 251.2;Macrophages: 198.9;Pancreatic endocrine cells: 590.1;Smooth muscle cells: 326.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "thalamus: 77.3" "Group enriched" "Detected in many" 32 "classical monocyte: 252.3;intermediate monocyte: 149.1;myeloid DC: 156.9;non-classical monocyte: 121.4;plasmacytoid DC: 324.5" "Group enriched" "Detected in all" 46 "dendritic cells: 324.5;monocytes: 252.3" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 2857.3;GAMG: 2417.8;HSkMC: 2675.6;hTCEpi: 1915.6;LHCN-M2: 2269.4;U-2197: 1916.3;U-87 MG: 3667.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA008612, HPA017019" Enhanced "Secreted to blood" NA NA 1600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 33: Fibroblasts - ECM organization" "HPA008612: AB_1857970, HPA017019: AB_2669511" "unprognostic (1.05e-1)" "prognostic unfavorable (1.03e-5)" "unprognostic (4.38e-3)" "prognostic favorable (1.17e-4)" "unprognostic (5.21e-3)" "unprognostic (5.53e-3)" "unprognostic (4.60e-2)" "unprognostic (8.71e-3)" "unprognostic (5.45e-2)" "prognostic unfavorable (1.14e-5)" "unprognostic (1.42e-3)" "unprognostic (2.26e-1)" "prognostic unfavorable (7.82e-10)" "unprognostic (8.81e-3)" "unprognostic (1.73e-2)" "unprognostic (3.42e-1)" "unprognostic (1.70e-3)" 133.2 55.3 9.5 164.0 10.4 25.9 112.2 10.0 25.5 51.8 51.9 92.8 48.2 59.7 41.6 28.7 59.7 146.1 95.5 10.4 11.5 124.0 132.1 89.7 66.2 15.8 11.9 25.4 22.4 18.4 77.6 457.6 15.7 69.5 84.4 2.8 68.3 58.9 34.8 314.1 65.3 291.0 12.2 121.1 67.4 7.6 77.3 57.7 40.4 41.7 44.4 138.9 39.0 14.0 102.2 405.6 0.8 3.8 1104.3 354.4 1.5 295.1 42.9 209.9 125.1 186.4 1276.3 0.1 181.6 2857.3 2417.8 498.0 1.0 981.4 208.0 2.3 0.1 0.1 451.6 501.3 718.9 0.7 3.9 2675.6 1915.6 77.9 93.1 827.5 188.1 0.2 0.2 3.8 2269.4 4.8 0.7 0.7 13.1 5.1 0.9 0.4 24.3 3.4 96.7 8.8 1.3 0.7 473.7 15.5 3.9 452.8 3.7 110.9 745.6 1419.3 59.8 1916.3 1139.6 0.3 0.7 1.9 3667.3 0.9 1077.5 1.6 252.3 1.0 0.9 149.1 1.0 1.0 1.0 2.0 156.9 0.4 0.3 1.0 5.3 6.2 121.4 324.5 0.5 108.5 9.5 10.4 10.0 25.5 10.4 11.5 15.8 11.9 15.7 12.2 77.3 14.0 12.4 3.2 21.4 0.0 6.3 119.4 4.8 141.8 4.6 0.4 1.9 5.5 8.9 4.3 21.8 1.8 0.0 9.9 146.5 1.3 0.0 67.5 2.4 2.3 57.9 16.4 3.5 8.8 0.4 112.6 8.5 113.5 0.5 1.7 5.1 0.0 21.0 25.7 251.8 1.7 0.0 7.8 6.1 292.9 251.2 1.9 10.2 198.9 49.8 4.7 151.1 0.3 6.2 0.0 0.0 590.1 0.0 2.2 1.9 1.0 0.1 2.7 8.5 0.2 26.3 156.8 326.1 0.2 0.9 1.9 55.7 19.4 8.5 10.8 0.9 2.5 THBS2 TSP2 ENSG00000186340 "Thrombospondin 2" P35442 6 169215780-169254050 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 86.8;Endometrial stromal cells: 71.1;Fibroblasts: 127.7;Langerhans cells: 69.8;Melanocytes: 56.9;Oligodendrocyte precursor cells: 40.7;Oligodendrocytes: 55.8;Smooth muscle cells: 33.7;Suprabasal keratinocytes: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 250.2;ASC TERT1: 200.3;BJ hTERT+: 88.6;BJ hTERT+ SV40 Large T+: 96.3;BJ hTERT+ SV40 Large T+ RasG12V: 117.8;HSkMC: 113.2;hTEC/SVTERT24-B: 127.2;U-2197: 107.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017716, HPA044304" Approved Approved "Nuclear speckles,Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 21000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear speckles, Cytosol" "CAB017716: , HPA044304: AB_2678891" "unprognostic (2.85e-2)" "unprognostic (1.41e-1)" "unprognostic (5.87e-2)" "unprognostic (8.90e-2)" "unprognostic (3.64e-2)" "unprognostic (8.73e-2)" "unprognostic (2.93e-1)" "unprognostic (5.10e-3)" "unprognostic (1.39e-1)" "unprognostic (4.71e-2)" "unprognostic (4.00e-2)" "unprognostic (2.56e-1)" "prognostic unfavorable (3.77e-6)" "unprognostic (2.19e-3)" "unprognostic (4.38e-2)" "unprognostic (4.16e-2)" "unprognostic (2.48e-3)" 52.9 7.9 5.5 14.8 15.4 0.0 36.2 10.9 7.7 63.1 0.2 20.4 2.5 50.0 0.7 12.0 34.7 50.4 44.2 6.5 13.1 8.3 8.2 19.8 3.3 17.1 18.2 33.2 5.6 1.7 9.5 2.2 21.4 9.7 2.4 0.1 8.2 2.5 3.4 41.1 9.2 21.3 11.3 3.3 5.4 2.3 15.0 0.6 17.0 1.8 1.2 29.1 30.8 19.3 0.2 0.0 2.5 1.1 250.2 200.3 0.0 76.8 88.6 96.3 117.8 0.4 0.0 0.1 0.1 76.1 0.2 0.1 2.4 3.2 22.5 0.0 0.0 0.0 0.0 0.0 73.1 0.3 0.0 113.2 0.0 127.2 0.0 0.2 0.0 0.0 0.0 0.1 3.7 0.0 0.1 1.7 16.3 0.0 0.6 0.0 0.1 1.1 0.0 0.4 0.3 0.2 0.2 0.1 0.0 0.2 0.0 0.7 0.0 46.1 0.4 107.6 9.3 0.1 0.7 0.0 30.6 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 15.4 10.9 7.7 6.5 13.1 17.1 18.2 21.4 11.3 15.0 19.3 3.5 6.4 0.0 6.8 0.0 86.8 1.6 0.1 1.8 0.4 2.2 1.8 5.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.2 3.1 71.1 4.6 0.0 0.0 1.2 0.0 0.0 127.7 1.1 1.4 0.0 0.0 15.4 0.0 0.3 0.0 1.7 0.0 0.0 0.0 69.8 0.3 8.1 1.2 56.9 6.5 0.0 0.2 0.0 40.7 55.8 0.5 0.0 16.1 0.0 1.9 0.0 4.4 0.0 0.2 0.0 1.0 33.7 0.0 0.4 1.2 42.3 0.1 2.1 5.5 0.0 0.9 TIAM1 ENSG00000156299 "TIAM Rac1 associated GEF 1" Q13009 21 31118416-31559977 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 207.9" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 327.3;Microglial cells: 133.0;Oligodendrocyte precursor cells: 120.6;Oligodendrocytes: 124.6;Suprabasal keratinocytes: 143.3" "Cancer enhanced" "Detected in many" "testis cancer: 15.1" "Region enriched" "Detected in all" 4 "cerebellum: 207.9" "Group enriched" "Detected in many" 5 "classical monocyte: 17.4;intermediate monocyte: 15.3;memory CD4 T-cell: 12.5;myeloid DC: 9.6;naive CD4 T-cell: 16.2;NK-cell: 11.3;non-classical monocyte: 22.0;T-reg: 27.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 34.5;HEL: 34.7;HMC-1: 29.1;RT4: 35.5;SCLC-21H: 32.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 245.9" "CAB010416, HPA034853" Enhanced Supported "Nucleoplasm,Nuclear membrane,Cell Junctions,Cytokinetic bridge,Cytosol" Yes NA "Cluster 27: Non-specific - Gene expression" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cell Junctions" "Nuclear membrane, Cytokinetic bridge, Cytosol" "CAB010416: AB_2240410, HPA034853: " "unprognostic (9.59e-2)" "unprognostic (7.44e-3)" "unprognostic (5.64e-3)" "unprognostic (1.07e-1)" "unprognostic (1.58e-1)" "unprognostic (2.81e-3)" "unprognostic (2.84e-2)" "unprognostic (3.73e-1)" "unprognostic (8.08e-2)" "unprognostic (2.70e-3)" "unprognostic (7.97e-3)" "unprognostic (9.52e-2)" "unprognostic (1.20e-3)" "unprognostic (2.38e-3)" "unprognostic (1.61e-1)" "unprognostic (1.04e-2)" "unprognostic (2.21e-1)" 7.2 12.7 40.3 6.6 35.2 2.8 5.4 207.9 49.2 17.8 12.5 5.1 1.7 9.9 3.2 39.7 11.0 4.6 5.5 51.8 26.5 5.5 7.9 5.8 11.1 26.7 33.4 3.3 2.2 0.3 12.9 4.3 36.1 9.0 3.1 8.6 5.6 3.3 0.9 27.2 5.0 11.1 27.5 5.2 2.4 10.5 37.3 18.7 1.9 0.8 11.1 12.1 18.5 28.6 2.9 1.0 21.7 1.3 0.4 4.9 34.5 0.0 0.0 2.7 0.9 0.2 3.9 7.6 1.5 0.5 4.0 5.1 2.5 4.4 4.3 0.6 12.0 34.7 0.7 0.2 0.5 0.0 29.1 2.2 1.5 14.7 5.9 2.6 0.0 11.3 0.0 10.9 11.1 14.7 5.4 0.2 7.1 5.3 9.4 7.0 6.8 0.0 3.3 35.5 32.6 8.1 1.5 11.4 1.3 7.5 4.7 0.1 0.2 3.1 12.5 0.0 1.5 12.3 9.9 6.6 7.2 2.6 24.2 1.5 17.4 0.0 0.5 15.3 3.1 0.1 12.5 2.4 9.6 0.0 16.2 1.0 1.0 11.3 22.0 0.5 27.8 5.9 40.3 35.2 207.9 49.2 51.8 26.5 26.7 33.4 36.1 27.5 37.3 28.6 3.7 3.2 2.3 21.2 1.7 83.7 65.6 3.0 22.8 8.9 4.9 1.9 1.1 1.5 11.8 0.0 2.1 10.1 8.0 1.3 0.0 1.8 11.7 25.2 2.2 31.4 5.4 2.7 43.9 0.7 29.7 11.4 2.0 28.4 24.1 2.0 35.0 5.5 8.1 74.0 327.3 0.4 10.2 22.9 73.4 11.3 34.5 26.3 10.6 133.0 37.3 35.2 4.1 120.6 124.6 1.8 11.6 58.3 3.2 30.8 0.0 0.5 1.2 4.6 6.6 0.9 2.1 1.3 9.8 60.2 143.3 10.7 16.3 82.6 1.2 106.7 TMEM108 "CT124, MGC3040" ENSG00000144868 "Transmembrane protein 108" Q6UXF1 3 133038391-133397775 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 35.2;skeletal muscle: 23.1" "Cell type enhanced" "Detected in many" "Astrocytes: 209.9;Excitatory neurons: 357.3;Inhibitory neurons: 475.3;Oligodendrocyte precursor cells: 480.0" "Cancer enhanced" "Detected in many" "glioma: 4.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 24.2;LHCN-M2: 13.8;SCLC-21H: 21.0;SH-SY5Y: 92.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063350 Enhanced Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 55000 "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Nucleoli, Vesicles" "HPA063350: AB_2684993" "unprognostic (4.75e-2)" "unprognostic (1.73e-2)" "unprognostic (9.00e-2)" "unprognostic (1.92e-2)" "unprognostic (3.07e-3)" "unprognostic (3.17e-1)" "unprognostic (1.28e-1)" "unprognostic (3.65e-2)" "unprognostic (2.06e-4)" "unprognostic (2.08e-1)" "unprognostic (7.27e-4)" "unprognostic (1.11e-1)" "unprognostic (3.03e-4)" "unprognostic (1.60e-3)" "unprognostic (1.61e-2)" "unprognostic (6.12e-2)" "unprognostic (1.36e-2)" 1.4 11.3 6.3 1.5 9.6 0.2 1.5 3.4 10.0 2.0 3.2 1.5 0.4 2.4 0.6 9.6 1.7 0.8 6.8 9.6 2.9 0.4 0.1 11.0 1.7 0.0 4.1 0.3 0.3 3.0 2.2 2.4 4.0 1.0 1.3 35.2 1.3 2.0 23.1 1.4 1.6 5.5 0.0 1.3 1.3 13.9 7.9 1.3 3.1 7.0 2.3 8.3 0.8 0.8 0.0 0.0 4.1 0.0 0.0 0.1 0.0 0.2 0.0 1.1 0.0 0.3 0.0 0.1 1.0 0.0 0.0 0.1 0.2 0.0 0.7 1.0 1.8 8.5 0.0 0.0 0.0 0.0 24.2 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.1 13.8 0.7 0.1 0.3 3.8 0.0 0.0 0.0 4.8 0.1 1.1 0.0 21.0 92.6 0.0 0.1 0.3 5.5 0.2 0.0 0.0 0.1 0.1 0.0 3.4 1.3 0.0 0.7 1.8 0.0 3.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 9.6 3.4 10.0 9.6 2.9 0.0 4.1 4.0 0.0 7.9 0.8 0.6 3.2 4.6 209.9 0.0 2.4 0.5 0.2 0.0 10.4 1.3 2.8 1.7 1.5 5.0 0.0 102.2 1.8 0.0 0.0 0.0 0.0 80.6 1.0 0.6 1.3 0.0 0.0 357.3 0.4 8.6 4.6 4.1 0.2 1.3 5.5 0.4 0.0 0.3 1.7 475.3 0.0 0.0 0.0 0.8 38.2 0.9 0.1 0.0 33.7 0.0 5.7 0.0 480.0 22.2 0.3 0.0 0.7 1.2 0.2 0.0 0.0 0.0 57.6 0.0 6.8 3.3 17.2 11.2 0.0 1.6 1.1 1.0 4.9 0.0 0.4 TMEM119 OBIF ENSG00000183160 "Transmembrane protein 119" Q4V9L6 12 108589851-108598320 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Biomineralization, Differentiation, Osteogenesis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Early spermatids: 8.3;Fibroblasts: 30.5;Late spermatids: 9.3;Melanocytes: 8.8;Microglial cells: 15.0;Peritubular cells: 24.0;Smooth muscle cells: 9.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "ASC diff: 559.2;ASC TERT1: 152.6;BJ hTERT+: 168.0;fHDF/TERT166: 81.9;HSkMC: 238.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051870, HPA052650" Enhanced NA NA "Cluster 6: Non-specific - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA051870: AB_2681645, HPA052650: AB_2681901" "unprognostic (4.90e-2)" "unprognostic (2.66e-1)" "unprognostic (6.84e-2)" "unprognostic (5.97e-2)" "unprognostic (2.35e-1)" "unprognostic (3.29e-2)" "unprognostic (6.67e-2)" "unprognostic (8.40e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.61e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.06e-6)" "unprognostic (1.29e-2)" "unprognostic (8.76e-3)" "unprognostic (1.40e-2)" "unprognostic (1.87e-2)" 29.6 8.0 7.6 16.2 8.9 3.0 27.1 8.5 9.2 61.0 5.3 12.6 15.1 18.9 14.1 6.9 11.9 35.8 9.4 7.7 9.3 6.0 0.9 37.6 47.8 17.2 12.1 1.4 7.5 5.6 6.1 6.6 14.9 12.7 15.1 0.9 6.8 26.0 1.6 13.9 23.1 11.2 13.4 11.4 10.5 5.9 16.4 5.1 21.7 1.7 27.2 32.2 18.4 21.9 0.1 0.3 1.3 0.7 559.2 152.6 0.8 11.8 168.0 0.4 3.0 0.2 0.6 0.3 0.4 81.9 0.3 0.2 0.1 0.2 0.1 0.5 0.0 0.3 0.6 1.0 7.2 0.3 1.2 238.4 0.3 7.0 0.1 0.7 0.1 0.2 0.5 0.5 0.5 0.7 0.3 1.6 0.1 0.0 0.9 0.6 0.9 0.8 0.1 0.7 0.2 39.5 0.0 0.3 0.3 4.5 0.2 1.8 1.2 13.1 0.4 11.2 0.5 2.6 3.1 0.6 6.8 0.5 0.1 1.4 0.2 0.3 0.2 0.1 0.2 0.2 0.4 0.2 0.1 0.4 0.3 0.3 1.4 0.2 0.4 0.2 0.1 0.1 7.6 8.9 8.5 9.2 7.7 9.3 17.2 12.1 14.9 13.4 16.4 21.9 1.3 0.0 0.0 0.0 0.2 3.8 0.1 0.0 0.6 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 8.3 0.2 5.8 1.3 0.0 0.0 0.0 0.0 0.2 30.5 0.0 0.2 0.0 0.0 0.7 0.0 1.4 0.0 0.0 0.0 0.0 1.9 4.4 9.3 4.1 1.1 8.8 15.0 1.6 0.0 0.0 0.0 0.0 0.1 1.1 24.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.8 9.7 0.1 0.1 0.0 3.7 0.3 0.7 0.5 0.0 0.1 TMEM200B TTMB ENSG00000253304 "Transmembrane protein 200B" Q69YZ2 1 29119429-29123903 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 60.6" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 8.8;Fibroblasts: 6.1;Leydig cells: 12.8;Melanocytes: 8.8;Peritubular cells: 15.1;Sertoli cells: 6.6;Smooth muscle cells: 9.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 28.2;BJ hTERT+ SV40 Large T+: 26.7;BJ hTERT+ SV40 Large T+ RasG12V: 29.5;fHDF/TERT166: 29.0;HBF TERT88: 25.3" "Low region specificity" "Detected in all" HPA055254 Uncertain NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA055254: AB_2682760" "unprognostic (2.55e-1)" "unprognostic (2.12e-2)" "unprognostic (8.25e-3)" "unprognostic (1.39e-1)" "unprognostic (4.71e-3)" "unprognostic (6.84e-2)" "unprognostic (1.91e-1)" "unprognostic (1.52e-2)" "unprognostic (6.25e-2)" "unprognostic (1.33e-1)" "unprognostic (6.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.24e-2)" "unprognostic (1.81e-2)" "unprognostic (2.70e-1)" "unprognostic (1.12e-1)" "unprognostic (7.16e-3)" 16.8 4.4 2.0 4.0 6.3 0.0 11.8 6.9 3.3 47.2 6.6 29.5 2.3 60.6 7.8 5.6 21.5 7.3 7.0 1.9 2.4 9.4 8.4 10.5 1.2 2.2 2.1 33.3 2.5 26.1 3.6 6.5 2.2 24.6 4.1 0.3 4.1 39.7 2.2 5.8 9.2 35.1 2.0 6.4 6.4 13.3 2.6 1.0 5.0 2.6 1.3 20.9 24.3 2.1 21.0 0.0 3.4 0.0 28.2 23.4 1.1 14.4 22.6 26.7 29.5 1.1 2.3 0.0 3.5 29.0 9.8 0.4 2.3 0.0 25.3 0.1 0.9 0.1 5.7 1.8 19.6 0.0 0.1 12.5 2.7 20.1 3.9 1.1 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.3 1.9 0.0 5.8 0.0 0.0 0.0 0.3 0.1 0.0 1.7 20.7 0.0 0.1 9.5 0.0 0.0 0.0 9.4 0.4 19.9 0.4 0.0 0.0 0.0 11.6 0.0 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 6.3 6.9 3.3 1.9 2.4 2.2 2.1 2.2 2.0 2.6 2.1 2.0 3.2 0.6 0.7 0.2 1.9 0.4 0.2 2.8 0.8 0.6 1.8 1.0 1.5 0.7 0.0 2.1 0.1 0.2 0.1 0.0 0.0 0.1 1.0 8.8 1.3 0.0 0.0 0.3 0.0 0.5 6.1 0.0 0.6 0.0 0.0 1.1 1.2 0.1 0.0 0.1 0.0 0.0 0.0 1.2 2.4 12.8 0.1 8.8 1.9 0.1 0.1 0.0 0.0 0.1 0.0 0.1 15.1 0.0 0.3 0.0 5.9 0.4 1.9 6.6 1.1 9.5 0.3 0.6 0.2 0.6 0.5 0.4 0.0 0.0 0.3 TMEM35B ZMYM6NB ENSG00000243749 "Transmembrane protein 35B" Q8NCS4 1 34981535-34985353 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Alveolar cells type 1: 22.4;Alveolar cells type 2: 13.4;Club cells: 6.2;granulocytes: 8.8;Respiratory ciliated cells: 15.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 115.3;CAPAN-2: 113.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051024 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 44: Non-specific - Transcription" "Cluster 5: Breast - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Nucleoli" "HPA051024: AB_2681316" "unprognostic (3.34e-3)" "unprognostic (2.77e-3)" "unprognostic (4.25e-1)" "unprognostic (2.12e-2)" "unprognostic (5.52e-2)" "unprognostic (2.08e-2)" "unprognostic (2.06e-1)" "unprognostic (4.31e-2)" "unprognostic (1.06e-1)" "unprognostic (7.51e-3)" "unprognostic (2.32e-1)" "unprognostic (9.41e-2)" "unprognostic (2.03e-2)" "unprognostic (1.86e-1)" "unprognostic (5.49e-2)" "unprognostic (4.53e-3)" "unprognostic (1.07e-1)" 48.9 36.0 12.6 25.1 12.5 13.6 40.1 12.4 18.5 41.6 16.9 27.4 16.6 36.2 39.0 15.4 41.3 41.0 32.3 12.4 13.1 36.8 40.1 44.2 40.0 13.8 12.8 32.5 29.6 29.8 21.8 63.4 13.7 30.4 26.6 2.2 25.8 34.8 8.6 13.3 27.6 30.1 13.7 32.5 24.4 22.6 13.4 29.7 44.7 20.4 30.9 36.2 33.3 14.4 25.8 19.5 4.2 7.3 115.3 67.1 9.3 27.7 46.2 19.1 25.8 19.4 113.1 12.6 42.1 28.4 30.3 27.2 8.1 23.4 15.0 49.2 12.9 27.2 9.0 23.1 63.2 18.0 27.5 67.7 21.3 17.4 36.6 39.1 38.3 26.8 17.5 36.2 34.2 16.2 13.3 18.6 20.2 0.0 13.6 17.7 37.3 4.0 53.6 24.9 11.1 3.5 42.4 0.6 39.5 21.3 10.3 27.9 39.4 25.6 24.0 22.7 15.8 20.9 12.7 8.9 25.7 29.4 22.2 161.3 101.2 112.4 188.7 118.6 202.9 108.9 205.0 208.3 71.3 89.9 177.7 179.9 31.4 165.4 100.4 159.5 232.4 182.9 12.6 12.5 12.4 18.5 12.4 13.1 13.8 12.8 13.7 13.7 13.4 14.4 0.6 22.4 13.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 6.2 0.0 0.0 0.1 0.2 0.0 0.0 1.0 0.0 0.3 0.7 2.1 0.0 0.0 0.0 0.2 0.2 2.0 0.0 0.3 8.8 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 15.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 TMEM98 DKFZP564K1964 ENSG00000006042 "Transmembrane protein 98" Q9Y2Y6 17 32927910-32945106 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 250.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "plasmacytoid DC: 4.1" "Lineage enriched" "Detected in single" 11 "dendritic cells: 4.1" "Cell line enhanced" "Detected in many" "CACO-2: 277.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040473, HPA053385" Uncertain Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA040473: AB_10794876, HPA053385: AB_2682134" "unprognostic (1.55e-2)" "unprognostic (5.15e-2)" "unprognostic (4.36e-3)" "unprognostic (7.20e-2)" "unprognostic (1.19e-1)" "unprognostic (7.93e-2)" "prognostic unfavorable (8.14e-4)" "prognostic favorable (7.10e-4)" "unprognostic (6.38e-2)" "unprognostic (2.22e-1)" "unprognostic (3.41e-1)" "unprognostic (9.18e-3)" "prognostic favorable (3.85e-4)" "unprognostic (5.16e-2)" "unprognostic (1.44e-1)" "unprognostic (1.30e-2)" "unprognostic (2.58e-1)" 56.3 50.6 48.9 17.3 84.1 4.7 44.5 75.3 64.1 68.6 161.9 90.0 102.5 100.4 74.2 27.9 96.5 93.9 44.3 51.2 56.9 36.5 27.5 58.1 5.7 72.8 77.4 191.9 88.5 53.7 23.9 28.2 69.7 80.7 96.3 15.7 50.1 23.9 5.3 24.6 118.4 62.3 51.9 19.6 101.6 20.7 75.0 4.4 47.7 14.6 7.7 50.7 42.6 109.3 7.4 27.2 115.5 0.2 154.7 138.0 1.1 114.2 153.2 59.2 126.5 277.6 8.1 1.6 1.7 144.0 2.1 0.9 74.2 30.1 34.5 24.7 92.0 4.6 0.1 124.5 71.5 0.3 1.7 116.3 29.7 74.7 12.1 31.6 154.8 40.7 78.1 0.3 162.9 0.2 0.1 0.7 77.0 83.1 42.0 0.2 108.4 0.5 13.6 49.0 9.8 158.3 2.7 0.0 89.8 72.6 36.5 0.2 128.2 83.8 78.1 1.0 0.2 9.2 3.8 0.1 42.9 0.1 46.2 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.0 4.1 0.0 0.1 48.9 84.1 75.3 64.1 51.2 56.9 72.8 77.4 69.7 51.9 75.0 109.3 7.6 41.7 24.8 6.2 0.6 25.1 76.1 111.5 27.3 1.4 32.4 104.5 14.1 72.9 61.0 46.0 0.0 8.1 0.7 109.2 5.9 81.0 18.2 14.7 48.5 7.8 97.9 2.7 0.6 66.4 7.3 127.2 40.8 12.1 3.8 87.8 29.6 13.0 5.7 0.0 0.3 145.7 40.7 0.6 15.9 14.9 120.5 2.0 44.4 1.9 0.0 106.3 0.0 3.0 173.0 88.2 97.9 151.6 0.2 68.1 250.9 37.2 54.6 4.8 65.7 22.1 55.5 40.7 27.7 17.1 12.6 7.1 2.4 132.6 166.6 68.6 TNFAIP6 "TSG-6, TSG6" ENSG00000123610 "TNF alpha induced protein 6" P98066 2 151357592-151380046 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "urinary bladder: 196.0" "Cell type enhanced" "Detected in many" "Early spermatids: 443.9;Fibroblasts: 302.3;Langerhans cells: 137.4;Melanocytes: 74.7" "Cancer enhanced" "Detected in many" "renal cancer: 27.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 22 "neutrophil: 183.0" "Lineage enriched" "Detected in many" 22 "granulocytes: 183.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 67.5;HHSteC: 40.3;hTEC/SVTERT24-B: 54.9;SH-SY5Y: 21.6;U-2197: 44.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB032719, HPA050884" Uncertain "Secreted to blood" NA NA 100000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB032719: AB_2204650, HPA050884: AB_2681261" "unprognostic (1.31e-1)" "prognostic unfavorable (8.18e-5)" "unprognostic (8.66e-2)" "unprognostic (2.51e-2)" "unprognostic (1.15e-3)" "unprognostic (3.26e-3)" "unprognostic (3.75e-4)" "unprognostic (4.49e-3)" "unprognostic (1.22e-1)" "unprognostic (1.90e-1)" "unprognostic (5.87e-3)" "unprognostic (1.08e-1)" "prognostic unfavorable (5.59e-4)" "unprognostic (1.06e-2)" "unprognostic (1.25e-2)" "unprognostic (5.46e-2)" "prognostic unfavorable (9.16e-5)" 15.6 0.5 1.9 27.6 2.2 7.6 11.1 1.5 2.8 9.2 1.2 6.3 0.7 2.0 0.3 2.2 2.2 19.8 15.4 1.7 2.2 0.4 1.2 11.0 0.6 1.6 2.2 0.5 1.2 0.3 0.4 1.8 1.9 3.2 2.8 0.0 3.4 0.9 1.7 2.7 2.2 7.2 1.6 3.0 4.0 10.6 2.6 1.4 1.6 2.8 0.5 196.0 1.6 2.3 0.0 0.0 0.0 0.0 3.8 15.5 0.0 2.5 67.5 2.5 12.4 0.0 0.0 0.0 0.8 1.1 1.4 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.3 0.0 40.3 0.0 0.0 19.5 0.0 54.9 3.8 2.3 0.1 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.3 0.0 15.5 0.0 1.1 0.0 0.0 0.0 0.0 21.6 0.5 0.0 0.0 0.4 0.0 0.0 0.0 2.2 4.4 44.3 0.8 0.0 0.0 0.0 4.8 0.7 3.3 0.0 8.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 183.0 0.0 2.1 0.0 0.0 2.5 1.9 2.2 1.5 2.8 1.7 2.2 1.6 2.2 1.9 1.6 2.6 2.3 4.5 3.2 1.7 1.3 1.1 64.7 0.9 11.1 0.0 0.0 1.5 1.4 2.2 0.0 1.5 0.0 0.0 0.1 0.3 0.1 0.0 2.8 443.9 2.9 2.7 7.3 0.0 0.8 0.7 0.0 0.9 302.3 0.5 10.6 2.5 0.0 1.4 0.0 1.4 0.0 0.4 0.0 0.0 6.9 137.4 38.5 2.5 49.6 74.7 1.9 5.9 0.0 0.0 13.6 7.1 1.5 0.0 0.4 1.4 3.0 0.0 0.2 0.2 0.0 0.0 40.6 45.5 10.7 1.9 1.0 53.0 1.8 6.0 0.3 0.0 3.8 TNN TNW ENSG00000120332 "Tenascin N" Q9UQP3 1 175067833-175148075 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 12.0;breast: 4.9" "Cell type enhanced" "Detected in some" "Adipocytes: 6.1;Fibroblasts: 7.5;Hepatic stellate cells: 2.5;Langerhans cells: 2.5;Smooth muscle cells: 10.4" "Cancer enhanced" "Detected in some" "breast cancer: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 5.6;NB-4: 3.6;THP-1: 11.1;U-266/70: 2.7;U-937: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB010907, HPA026726, HPA026764" Uncertain "Secreted to extracellular matrix" NA NA 34000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "CAB010907: AB_477565, HPA026726: AB_10601771, HPA026764: AB_10601859" "unprognostic (1.16e-3)" "unprognostic (2.23e-2)" "unprognostic (1.35e-1)" "unprognostic (2.21e-2)" "unprognostic (1.34e-1)" "unprognostic (1.48e-1)" "unprognostic (1.48e-1)" "unprognostic (3.55e-1)" "unprognostic (5.25e-3)" "unprognostic (1.01e-2)" "unprognostic (4.69e-1)" "unprognostic (5.07e-1)" "unprognostic (1.08e-3)" "unprognostic (1.76e-2)" "unprognostic (9.38e-3)" "unprognostic (1.89e-2)" "unprognostic (1.02e-2)" 12.0 0.2 0.0 0.1 0.1 0.0 4.9 0.0 0.1 0.1 0.1 0.3 0.8 0.0 0.0 0.1 0.0 1.7 0.3 0.2 0.0 0.4 1.3 0.4 0.1 0.0 0.1 0.0 0.3 0.8 2.0 0.1 0.0 0.0 0.1 0.0 3.2 0.0 0.0 3.1 0.4 0.4 0.1 0.4 0.4 0.1 0.1 0.1 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 11.1 0.0 0.0 0.0 0.0 0.0 2.7 0.4 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.1 6.1 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.7 0.0 0.1 7.5 0.0 0.1 0.0 0.0 2.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 2.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 10.4 0.4 1.4 0.0 1.8 0.1 0.1 0.0 0.0 0.1 TPBG "5T4, 5T4-AG" ENSG00000146242 "Trophoblast glycoprotein" Q13641 6 82363206-82367420 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 120.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "MAIT T-cell: 1.4" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Cell line enhanced" "Detected in many" "BJ hTERT+: 94.6;hTCEpi: 115.2;hTEC/SVTERT24-B: 98.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA010554 Enhanced Approved Nucleoplasm NA NA 310000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA010554: AB_1858206" "unprognostic (3.03e-1)" "unprognostic (1.46e-2)" "prognostic unfavorable (6.68e-4)" "unprognostic (1.06e-1)" "unprognostic (4.52e-3)" "unprognostic (7.47e-3)" "unprognostic (8.55e-2)" "unprognostic (3.55e-3)" "unprognostic (8.39e-2)" "unprognostic (3.42e-2)" "unprognostic (8.02e-2)" "unprognostic (4.94e-1)" "unprognostic (3.77e-1)" "unprognostic (7.46e-2)" "unprognostic (1.06e-1)" "unprognostic (1.54e-1)" "unprognostic (5.57e-2)" 19.9 2.5 1.6 3.3 20.6 0.5 17.3 0.4 5.7 24.2 0.6 8.5 3.5 15.8 2.6 26.3 14.9 6.9 9.1 0.2 4.2 10.7 1.5 7.5 1.9 8.2 11.4 6.0 8.3 4.2 14.2 6.2 9.3 15.3 3.0 0.2 20.1 7.0 2.9 15.9 8.0 6.7 3.1 9.9 9.0 3.6 3.6 4.2 15.7 1.9 3.0 35.1 20.2 3.6 17.1 27.6 8.7 21.2 35.2 40.4 17.6 84.9 94.6 16.7 22.0 3.9 26.9 0.0 9.6 39.5 51.9 37.3 10.3 44.6 13.9 0.0 14.5 11.9 13.1 0.8 29.1 0.9 9.2 25.8 115.2 98.5 34.1 12.9 4.5 0.7 2.3 0.2 3.9 37.8 0.0 0.0 12.5 8.8 22.3 0.0 19.4 0.2 24.4 25.8 4.4 16.9 20.9 28.3 0.0 16.2 49.4 3.5 10.8 15.1 15.8 33.5 19.2 0.1 0.0 0.0 71.3 1.3 17.8 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 20.6 0.4 5.7 0.2 4.2 8.2 11.4 9.3 3.1 3.6 3.6 16.4 12.8 6.5 2.3 0.2 67.9 78.2 120.3 68.3 1.1 44.6 24.0 2.1 21.5 62.4 55.2 0.0 42.7 0.4 9.0 0.0 35.8 8.6 29.2 38.7 25.4 1.2 0.0 21.3 45.4 82.5 48.0 14.8 68.0 0.0 3.8 11.0 0.2 3.6 1.7 0.9 20.2 75.3 0.6 11.5 6.5 12.8 2.3 17.8 7.5 0.1 2.1 0.0 2.0 3.2 38.2 17.8 6.0 0.0 51.9 1.9 0.7 29.9 0.3 32.9 55.6 47.0 13.7 11.8 25.2 31.3 65.9 3.5 9.7 10.8 78.8 TRIL KIAA0644 ENSG00000255690 "TLR4 interactor with leucine rich repeats" Q7L0X0 7 28953358-28958330 "Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 68.0" "Cell type enriched" "Detected in many" 4 "Astrocytes: 72.1" "Cancer enhanced" "Detected in many" "glioma: 20.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 22.2;SH-SY5Y: 40.0;SK-BR-3: 35.7;T-47d: 15.8" "Low region specificity" "Detected in all" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.26e-3)" "unprognostic (3.29e-2)" "unprognostic (5.89e-2)" "prognostic unfavorable (3.23e-4)" "unprognostic (2.66e-2)" "unprognostic (1.16e-1)" "unprognostic (1.34e-1)" "unprognostic (1.58e-2)" "unprognostic (8.77e-2)" "prognostic unfavorable (8.52e-4)" "unprognostic (4.27e-3)" "unprognostic (1.24e-1)" "unprognostic (1.07e-1)" "unprognostic (1.04e-2)" "unprognostic (1.28e-1)" "unprognostic (2.31e-2)" "unprognostic (2.07e-2)" 4.7 2.3 40.8 0.6 61.3 0.0 4.1 57.4 35.0 2.9 7.3 2.0 2.0 3.6 1.7 2.4 2.3 1.0 4.3 32.5 40.8 5.9 0.6 2.6 0.4 58.2 65.2 1.6 0.5 0.8 1.6 1.1 46.1 1.9 1.8 1.0 8.2 1.4 3.1 1.9 2.4 3.4 49.7 2.6 2.3 0.5 68.0 0.4 2.9 0.7 0.3 2.3 3.5 35.9 0.0 0.0 22.2 0.0 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 6.1 0.0 0.1 0.0 0.2 0.0 0.0 0.3 0.8 40.0 0.1 35.7 0.0 3.2 15.8 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.8 61.3 57.4 35.0 32.5 40.8 58.2 65.2 46.1 49.7 68.0 35.9 7.0 12.8 5.3 72.1 0.0 0.0 0.2 0.0 4.0 0.4 7.4 11.0 2.7 0.0 0.6 1.8 0.0 0.2 0.0 0.1 3.9 0.1 0.0 0.4 0.2 4.3 0.0 0.0 0.7 0.0 1.9 15.9 0.0 1.1 0.0 0.2 2.5 0.4 0.1 6.7 0.6 0.4 0.0 0.0 0.0 0.2 1.2 0.5 0.0 5.6 0.0 17.1 0.0 13.0 0.4 0.0 0.2 0.0 0.0 0.0 0.1 1.8 0.0 0.8 13.1 15.2 4.9 0.5 0.7 2.2 0.0 0.1 0.1 2.0 0.8 0.1 TRPS1 "GC79, LGCR" ENSG00000104447 "Transcriptional repressor GATA binding 1" Q9UHF7 8 115408496-115809673 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 60.8" "Cell type enhanced" "Detected in many" "Astrocytes: 758.7;Breast glandular cells: 243.2;Oligodendrocyte precursor cells: 280.5;Oligodendrocytes: 294.0" "Cancer enriched" "Detected in many" 8 "breast cancer: 49.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 4.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 47.4;SK-BR-3: 78.1;T-47d: 244.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060380, HPA071767" Enhanced Supported Nucleoplasm NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA060380: AB_2684270, HPA071767: AB_2732185" "unprognostic (4.34e-2)" "unprognostic (4.65e-2)" "unprognostic (1.73e-2)" "unprognostic (2.57e-1)" "unprognostic (1.87e-1)" "prognostic favorable (9.42e-4)" "unprognostic (2.23e-3)" "unprognostic (2.08e-1)" "unprognostic (9.31e-2)" "unprognostic (3.26e-1)" "prognostic unfavorable (3.16e-4)" "unprognostic (3.02e-1)" "unprognostic (2.17e-2)" "unprognostic (1.93e-2)" "unprognostic (1.64e-1)" "unprognostic (1.78e-2)" "unprognostic (3.07e-3)" 4.4 3.1 15.5 5.7 14.3 7.6 60.8 10.5 14.7 10.9 10.1 5.9 0.9 9.9 3.4 14.2 5.5 10.0 3.8 17.0 13.5 5.4 2.1 4.7 4.9 32.5 31.5 5.2 1.1 5.3 2.6 2.8 24.2 9.4 2.7 4.1 12.0 8.4 2.6 10.6 2.1 10.6 18.4 4.2 2.7 12.5 27.5 2.4 5.7 3.3 4.0 5.1 14.1 16.3 3.1 0.6 5.9 0.3 5.4 19.8 0.6 4.9 11.3 3.1 5.2 0.5 4.9 2.4 0.0 12.7 2.6 0.1 22.9 4.3 3.5 0.3 6.9 0.1 10.3 0.2 7.2 0.0 0.3 9.5 4.4 8.6 15.8 8.9 2.7 0.3 1.1 37.7 6.0 47.4 0.2 0.0 1.1 1.1 4.8 0.2 0.2 30.0 4.9 0.3 5.2 3.9 2.5 78.1 3.2 2.8 244.8 2.1 0.2 13.7 6.9 4.0 9.7 10.1 0.3 4.5 14.4 0.0 9.2 0.0 4.5 0.0 0.9 1.9 0.9 0.5 1.0 1.0 1.7 0.8 0.9 0.9 0.8 1.0 1.4 0.6 0.5 0.8 15.5 14.3 10.5 14.7 17.0 13.5 32.5 31.5 24.2 18.4 27.5 16.3 10.0 6.4 3.0 758.7 13.3 9.4 20.0 10.3 34.1 9.2 243.2 125.1 4.6 2.8 9.2 18.4 43.8 0.1 18.7 0.1 11.7 2.9 95.0 58.5 35.7 7.5 0.0 5.5 128.3 2.9 0.2 26.8 4.6 63.5 12.7 0.3 3.6 1.1 16.5 0.0 148.2 0.0 8.2 55.2 104.1 163.2 25.1 55.5 21.4 171.4 32.5 10.6 5.2 280.5 294.0 2.7 0.0 28.2 10.1 16.9 0.0 23.7 8.9 35.9 6.6 60.2 28.2 1.8 8.3 73.6 12.5 0.3 25.6 19.5 0.0 11.2 TSHZ2 "C20orf17, OVC10-2, TSH2, ZABC2, ZNF218" ENSG00000182463 "Teashirt zinc finger homeobox 2" Q9NRE2 20 52972358-53495330 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 395.6;Leydig cells: 468.2;Peritubular cells: 803.8;Theca cells: 396.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 3.0;T-reg: 2.4" "Lineage enriched" "Detected in single" 4 "T-cells: 3.0" "Cell line enhanced" "Detected in some" "AN3-CA: 26.7;ASC diff: 11.3;HeLa: 23.6;SiHa: 15.3;U-2197: 13.7" "Low region specificity" "Detected in all" HPA038123 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" Nucleoplasm "HPA038123: AB_10670657" "unprognostic (9.24e-3)" "unprognostic (1.58e-1)" "unprognostic (9.35e-2)" "unprognostic (1.13e-1)" "unprognostic (1.21e-4)" "unprognostic (3.30e-1)" "unprognostic (4.30e-1)" "unprognostic (1.28e-1)" "unprognostic (2.16e-1)" "unprognostic (3.23e-2)" "unprognostic (3.33e-1)" "unprognostic (3.14e-2)" "unprognostic (9.88e-8)" "unprognostic (6.26e-2)" "unprognostic (3.81e-2)" "unprognostic (3.37e-7)" "unprognostic (2.97e-3)" 21.5 14.8 3.4 4.5 4.7 0.2 10.6 2.9 4.3 9.0 0.0 7.3 2.3 6.8 16.5 8.2 8.7 12.4 3.7 5.7 8.9 3.3 12.6 2.9 3.9 5.9 8.2 18.4 3.5 5.4 2.7 1.3 5.5 5.4 2.0 1.7 12.9 13.6 1.6 5.9 2.8 8.8 10.3 5.1 6.1 4.8 8.1 2.0 5.3 2.6 3.4 7.6 5.7 7.5 0.0 0.0 1.8 26.7 11.3 2.8 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 6.8 0.0 0.1 0.0 0.1 0.0 5.2 1.4 0.0 23.6 0.0 0.3 0.0 0.6 4.1 3.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.7 4.4 15.3 0.1 0.0 0.7 0.0 0.0 0.0 0.1 2.6 13.7 0.0 0.1 0.3 0.0 2.7 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.4 2.1 0.1 0.0 0.4 3.0 0.2 0.6 0.1 0.0 0.1 2.4 0.5 3.4 4.7 2.9 4.3 5.7 8.9 5.9 8.2 5.5 10.3 8.1 7.5 171.4 0.0 0.6 32.7 7.0 45.4 19.9 43.8 37.0 6.7 24.4 161.5 2.8 54.3 41.6 36.8 2.1 1.3 1.3 0.1 0.0 52.2 11.1 32.7 144.4 125.7 6.6 0.0 188.2 9.8 0.5 93.3 3.1 68.9 1.3 395.6 11.7 92.1 1.2 0.0 58.1 1.9 18.3 1.3 16.6 20.3 468.2 2.8 12.4 104.9 1.9 39.0 1.0 23.6 4.9 6.8 2.7 803.8 16.0 27.5 0.8 0.4 19.9 1.9 39.5 10.9 48.2 2.6 1.8 43.9 40.5 0.8 24.2 396.9 2.6 8.2 TTC39B "C9orf52, FLJ33868" ENSG00000155158 "Tetratricopeptide repeat domain 39B" Q5VTQ0 9 15163622-15307360 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 64.4;Paneth cells: 65.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 2.0;gdT-cell: 2.9;MAIT T-cell: 3.9;memory CD4 T-cell: 4.0;memory CD8 T-cell: 4.6;naive CD4 T-cell: 4.7;naive CD8 T-cell: 2.9;NK-cell: 6.3;T-reg: 3.8" "Group enriched" "Detected in many" 6 "granulocytes: 2.0;NK-cells: 6.3;T-cells: 4.7" "Cell line enhanced" "Detected in many" "HEL: 40.9;RT4: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063162 Approved "Endoplasmic reticulum" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA063162: AB_2684952" "unprognostic (1.64e-1)" "unprognostic (9.32e-3)" "unprognostic (1.47e-2)" "unprognostic (7.89e-2)" "unprognostic (7.47e-2)" "unprognostic (1.06e-1)" "unprognostic (4.12e-2)" "prognostic favorable (9.64e-6)" "unprognostic (5.99e-2)" "unprognostic (4.77e-2)" "unprognostic (1.59e-1)" "unprognostic (6.89e-2)" "prognostic favorable (4.08e-7)" "unprognostic (3.31e-3)" "unprognostic (2.12e-2)" "unprognostic (5.19e-2)" "unprognostic (1.48e-1)" 1.9 2.6 2.9 4.0 2.5 1.5 4.8 10.8 7.0 4.3 1.8 6.7 5.7 3.5 1.9 8.8 3.3 6.9 1.3 1.5 4.6 9.0 5.4 4.6 6.1 7.0 2.9 2.9 3.9 1.9 3.9 1.2 7.2 2.3 5.6 2.9 3.0 1.9 1.8 9.6 5.6 4.2 2.5 3.8 5.5 5.7 4.7 3.4 2.6 1.3 6.0 3.6 4.7 2.9 3.9 0.8 1.2 5.6 5.3 9.9 1.2 5.0 9.1 3.9 9.3 0.8 1.6 0.0 0.6 6.3 4.6 3.4 0.9 6.2 3.3 4.5 0.8 40.9 1.7 7.3 8.8 0.0 0.8 9.7 4.7 8.1 9.0 2.8 5.6 3.3 0.1 9.1 10.0 1.3 2.2 0.2 1.6 12.3 1.2 0.4 3.0 1.9 8.3 23.0 2.9 0.5 1.2 2.9 0.9 1.8 12.7 2.5 4.2 2.2 1.8 3.1 1.4 0.1 0.1 0.0 2.1 0.5 1.1 2.0 0.7 0.9 2.9 0.5 3.9 0.2 4.0 4.6 0.4 0.6 4.7 2.9 0.4 6.3 0.7 0.1 3.8 2.5 2.9 2.5 10.8 7.0 1.5 4.6 7.0 2.9 7.2 2.5 4.7 2.9 7.5 12.8 19.8 10.4 7.0 17.3 7.8 19.1 10.8 25.5 9.0 4.4 4.1 10.0 15.8 7.3 0.0 3.2 18.0 40.6 17.6 6.6 43.2 11.8 10.1 7.4 12.7 0.4 44.0 21.8 1.1 10.0 22.4 7.7 29.1 3.6 7.5 11.6 4.1 13.5 64.4 16.1 24.4 3.1 9.2 33.2 7.2 16.7 7.2 12.2 2.9 14.9 11.3 24.6 2.3 10.5 65.0 12.8 5.5 11.5 30.3 35.5 25.3 4.3 0.0 9.4 12.4 4.7 3.0 8.6 21.5 4.1 22.3 6.8 17.3 14.4 TWIST2 "bHLHa39, Dermo-1, DERMO1" ENSG00000233608 "Twist family bHLH transcription factor 2" Q8WVJ9 2 238848032-238910534 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 83.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 95.4;Fibroblasts: 58.9;Leydig cells: 48.1;Peritubular cells: 39.1;Theca cells: 23.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 24 "eosinophil: 4.6" "Lineage enriched" "Detected in single" 47 "granulocytes: 4.6" "Cell line enhanced" "Detected in many" "ASC diff: 80.0;ASC TERT1: 50.5;BJ: 69.3;BJ hTERT+: 212.4;fHDF/TERT166: 97.4;U-2197: 81.3" "Low region specificity" "Detected in single" HPA062870 Supported Nucleoplasm,Nucleoli NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm Nucleoli "HPA062870: AB_2684888" "unprognostic (1.62e-2)" "unprognostic (1.33e-1)" "unprognostic (3.45e-1)" "unprognostic (3.81e-2)" "unprognostic (2.53e-4)" "unprognostic (1.83e-2)" "unprognostic (4.06e-2)" "unprognostic (1.13e-2)" "unprognostic (2.75e-2)" "unprognostic (2.33e-1)" "unprognostic (2.24e-1)" "unprognostic (1.17e-1)" "unprognostic (2.40e-9)" "unprognostic (1.59e-2)" "unprognostic (2.06e-1)" "unprognostic (1.98e-2)" "unprognostic (4.48e-2)" 59.7 4.0 0.3 1.4 0.3 0.4 43.3 0.3 0.5 83.0 0.6 22.9 0.3 31.3 0.7 10.1 30.4 1.7 10.8 0.4 0.3 1.8 0.7 9.3 0.3 0.4 0.8 39.9 1.8 0.1 8.3 3.1 0.4 25.7 1.1 0.0 7.9 3.7 1.8 33.5 8.9 2.9 0.4 2.3 10.3 1.9 0.3 0.1 8.2 1.0 0.4 21.3 54.2 0.5 0.1 4.5 0.4 0.0 80.0 50.5 0.1 69.3 212.4 31.0 46.4 0.0 0.0 0.0 2.1 97.4 2.5 0.5 0.7 5.4 22.5 0.0 7.3 0.0 4.0 0.2 13.7 0.0 1.6 11.8 2.9 15.0 12.5 3.7 4.2 0.0 0.0 0.0 4.2 0.0 0.0 0.0 3.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.1 0.0 0.7 0.0 0.9 11.8 1.2 2.2 81.3 0.8 0.0 0.0 0.0 0.3 2.1 4.3 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.5 0.4 0.3 0.4 0.8 0.4 0.4 0.3 0.5 2.5 0.0 2.6 0.0 0.1 2.0 16.0 0.0 7.4 0.0 0.5 0.4 0.6 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.4 3.6 95.4 1.3 0.0 0.0 4.4 0.0 1.9 58.9 0.0 2.1 1.3 0.5 2.9 0.1 2.2 0.0 0.2 0.0 0.0 0.0 3.6 1.2 48.1 0.8 1.8 12.2 0.4 0.0 8.2 0.5 0.1 0.1 0.0 39.1 0.0 20.5 0.0 0.0 0.0 0.0 0.0 1.1 9.6 0.5 3.3 0.2 1.7 1.6 1.6 23.2 0.0 3.7 VAV2 ENSG00000160293 "Vav guanine nucleotide exchange factor 2" P52735 9 133761894-133992604 "Plasma proteins, Predicted intracellular proteins" Angiogenesis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 48.3;Inhibitory neurons: 40.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 3.3" "Group enriched" "Detected in many" 22 "B-cells: 3.3;dendritic cells: 1.1;monocytes: 2.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003224 Uncertain Approved Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA003224: AB_1080554" "unprognostic (1.56e-1)" "unprognostic (1.10e-1)" "unprognostic (1.07e-2)" "unprognostic (1.09e-1)" "unprognostic (3.43e-1)" "unprognostic (1.19e-1)" "unprognostic (6.57e-2)" "unprognostic (1.16e-3)" "unprognostic (1.83e-2)" "unprognostic (3.74e-3)" "unprognostic (4.73e-2)" "unprognostic (9.16e-2)" "prognostic favorable (7.39e-7)" "unprognostic (8.64e-3)" "unprognostic (3.00e-2)" "prognostic unfavorable (4.33e-4)" "unprognostic (3.97e-2)" 8.4 26.8 9.3 10.7 8.8 3.0 7.7 7.4 9.8 12.0 10.9 11.8 20.9 9.9 7.2 6.7 12.2 10.8 7.4 11.6 9.9 21.3 46.1 16.8 13.3 11.6 16.0 5.5 38.6 10.8 8.0 13.1 13.2 10.2 9.6 3.0 13.2 8.9 2.0 6.1 22.4 6.9 8.9 13.9 9.5 4.4 9.9 6.2 13.8 2.3 13.3 11.4 7.9 8.4 12.5 21.6 33.3 13.5 9.0 15.1 85.8 24.6 13.5 20.3 12.2 33.0 19.0 3.6 19.6 24.6 26.2 72.8 31.6 53.0 10.4 21.3 7.3 4.2 28.3 37.2 33.4 10.3 1.6 15.0 33.5 17.9 25.3 13.6 22.9 7.3 7.3 6.0 14.2 63.5 0.8 5.1 16.3 54.3 20.5 33.9 28.2 12.1 46.1 22.4 36.9 24.9 64.7 42.7 8.8 21.3 26.0 14.5 18.7 28.6 16.0 28.7 34.5 0.4 0.3 6.8 19.1 8.8 18.0 0.0 0.8 0.0 0.0 2.0 0.0 3.3 0.0 0.0 1.1 2.1 0.0 0.0 0.0 0.0 1.4 0.7 0.0 0.5 9.3 8.8 7.4 9.8 11.6 9.9 11.6 16.0 13.2 8.9 9.9 8.4 4.8 0.0 5.4 20.5 11.2 5.1 3.0 10.1 4.0 1.9 6.7 5.6 4.7 21.5 7.5 36.8 0.0 1.3 0.6 27.0 3.9 9.2 2.5 6.9 6.4 6.6 28.2 0.4 8.5 12.5 18.3 5.0 9.7 13.9 0.0 24.6 6.8 48.3 6.2 0.0 40.9 9.8 6.1 5.4 7.2 7.9 7.2 7.7 1.8 8.4 9.3 4.2 2.1 31.2 2.6 24.7 15.6 6.0 3.3 6.3 35.7 13.6 3.3 1.8 13.1 6.4 8.8 0.1 3.8 2.1 2.7 1.0 1.7 12.0 13.5 2.1 VCAN "CSPG2, PG-M" ENSG00000038427 Versican P13611 5 83471618-83582303 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 975.7;Granulosa cells: 1131.8;Kupffer cells: 547.3;Macrophages: 605.6;monocytes: 948.1;Oligodendrocyte precursor cells: 1644.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 240.0;myeloid DC: 88.9" "Group enriched" "Detected in many" 20 "dendritic cells: 88.9;monocytes: 240.0" "Cell line enhanced" "Detected in many" "AF22: 300.5;HSkMC: 199.5;hTERT-RPE1: 959.0;RPTEC TERT1: 381.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004726, CAB008979" Supported Approved Vesicles "Secreted to blood" NA NA 12000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "CAB008979: , HPA004726: AB_1080561" "unprognostic (7.90e-2)" "unprognostic (9.03e-3)" "unprognostic (7.09e-2)" "unprognostic (6.06e-3)" "unprognostic (1.87e-1)" "unprognostic (4.49e-2)" "unprognostic (1.23e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (7.59e-4)" "unprognostic (4.36e-3)" "unprognostic (2.68e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (5.17e-4)" "prognostic unfavorable (1.41e-4)" "unprognostic (1.15e-1)" "unprognostic (4.44e-2)" "unprognostic (5.30e-3)" 42.0 23.9 18.6 74.9 20.8 32.6 15.6 24.2 23.0 29.4 5.2 11.3 3.8 17.8 1.8 3.8 8.6 30.5 45.0 25.7 27.8 6.5 2.7 34.4 2.3 36.1 19.3 2.1 3.1 2.4 2.1 73.5 31.3 6.8 10.7 0.2 7.6 4.2 3.9 11.2 5.7 48.0 28.9 13.9 7.7 4.8 44.9 2.7 6.6 6.8 1.9 48.3 7.2 42.7 0.2 5.6 300.5 0.1 119.8 81.5 0.1 2.3 6.2 2.1 1.5 3.1 0.2 0.0 45.2 111.5 3.9 0.0 0.4 0.4 1.7 0.1 9.8 2.1 0.0 2.3 5.5 0.1 0.0 199.5 0.1 127.6 1.2 959.0 0.1 0.0 0.0 0.1 64.6 0.0 0.5 0.0 51.1 0.0 10.3 0.0 63.0 0.1 381.0 0.0 3.6 15.5 0.0 0.0 0.2 33.2 0.2 0.5 116.5 90.6 0.5 168.3 179.0 0.0 0.1 0.2 41.8 0.1 16.4 8.3 240.0 0.5 0.5 31.3 0.3 0.2 0.1 0.1 88.9 0.1 0.1 0.0 3.9 0.5 3.5 1.7 0.0 94.0 18.6 20.8 24.2 23.0 25.7 27.8 36.1 19.3 31.3 28.9 44.9 42.7 23.4 19.2 19.8 128.9 5.5 38.6 10.6 14.9 1.2 0.0 1.8 1.9 8.2 44.3 17.5 25.8 0.0 5.9 7.4 0.0 0.0 1.9 3.0 64.4 975.7 29.9 0.0 5.2 1.5 0.7 7.0 348.1 3.6 241.3 12.6 1131.8 16.8 3.6 25.6 0.0 30.7 0.2 0.0 547.3 83.1 2.5 18.6 605.6 44.4 20.6 948.1 0.0 13.4 1644.7 1.5 32.3 1.1 117.8 2.5 2.5 0.0 1.8 16.2 0.0 0.0 11.0 80.6 0.9 1.2 1.1 28.7 11.5 12.7 1.6 0.3 0.9 VILL ENSG00000136059 "Villin like" O15195 3 37988059-38007188 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "intestine: 61.9;stomach 1: 97.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 221.7;Gastric mucus-secreting cells: 192.7;Paneth cells: 139.0;Proximal enterocytes: 165.6" "Cancer enhanced" "Detected in many" "pancreatic cancer: 22.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 25.0;OE19: 78.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA035675, HPA035676" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center" "HPA035675: AB_10671223, HPA035676: " "unprognostic (7.86e-3)" "unprognostic (7.37e-3)" "unprognostic (1.43e-1)" "unprognostic (2.03e-2)" "prognostic unfavorable (1.35e-4)" "prognostic favorable (1.75e-4)" "unprognostic (1.69e-1)" "unprognostic (1.44e-1)" "unprognostic (1.38e-1)" "unprognostic (2.18e-1)" "unprognostic (1.03e-2)" "unprognostic (2.95e-2)" "unprognostic (3.66e-3)" "unprognostic (5.55e-2)" "unprognostic (1.09e-1)" "unprognostic (1.15e-1)" "unprognostic (7.43e-3)" 5.4 3.7 8.7 11.0 9.0 12.6 6.4 6.6 10.6 9.5 6.4 46.8 61.9 5.7 1.5 7.2 6.7 15.7 6.4 8.6 7.8 5.3 1.4 7.7 9.8 8.3 8.4 6.8 3.4 1.2 5.1 4.1 8.0 16.0 26.6 1.2 5.7 4.0 1.2 9.1 61.7 4.1 8.0 11.8 97.5 5.4 8.2 10.2 7.4 1.4 6.3 17.5 7.4 7.2 8.2 0.1 0.2 0.4 2.8 2.2 0.8 2.3 1.9 2.3 2.2 6.1 25.0 3.9 3.5 1.6 0.0 1.9 1.8 0.2 0.5 0.8 0.0 7.3 0.1 0.6 3.4 7.7 9.5 3.3 2.2 2.2 0.0 0.0 4.5 16.1 7.3 2.3 2.6 0.1 12.4 8.7 0.2 78.4 0.0 4.8 0.0 2.0 0.8 9.8 0.1 0.3 0.0 0.5 1.8 0.0 0.7 12.4 2.8 1.0 0.3 3.0 0.0 1.4 3.1 1.2 0.6 10.9 5.0 0.0 3.2 0.0 6.8 2.0 7.4 3.5 4.4 3.9 2.1 4.6 5.6 4.2 0.1 3.4 1.4 3.8 5.8 4.1 8.7 9.0 6.6 10.6 8.6 7.8 8.3 8.4 8.0 8.0 8.2 7.2 4.9 9.6 7.4 10.4 7.2 2.3 5.7 25.5 6.8 0.9 3.3 2.9 1.9 8.6 46.1 0.0 0.0 3.0 13.3 221.7 0.0 3.4 6.2 1.5 2.7 4.5 9.6 6.1 5.5 16.9 3.4 6.7 192.7 1.5 8.2 6.1 5.3 0.3 2.4 1.7 3.0 64.4 14.2 1.9 2.4 19.9 3.7 4.0 1.8 3.7 4.2 28.1 7.2 2.5 1.2 38.7 139.0 2.6 4.4 6.2 165.6 1.6 40.5 0.8 0.0 4.3 7.1 5.4 3.4 3.1 1.4 1.0 8.1 5.6 50.5 33.4 WHRN "CIP98, DFNB31, PDZD7B, USH2D" ENSG00000095397 Whirlin Q9P202 9 114402080-114505473 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Hearing "Deafness, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 104.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 49.5;Endometrial stromal cells: 13.9;Glandular and luminal cells: 39.6;Plasma cells: 14.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 97.9;U-266/70: 67.8;U-266/84: 89.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (6.06e-3)" "unprognostic (1.02e-1)" "unprognostic (9.96e-2)" "unprognostic (4.27e-3)" "unprognostic (4.59e-1)" "unprognostic (7.07e-2)" "unprognostic (3.66e-2)" "unprognostic (7.25e-2)" "unprognostic (6.13e-3)" "unprognostic (3.43e-2)" "prognostic favorable (2.28e-4)" "unprognostic (1.03e-1)" "unprognostic (1.71e-3)" "unprognostic (3.21e-2)" "unprognostic (1.92e-1)" "unprognostic (1.25e-2)" "unprognostic (3.44e-1)" 5.8 104.7 21.7 2.3 33.5 2.6 5.9 24.0 28.9 17.8 47.2 12.4 3.8 36.4 4.1 5.6 11.5 2.3 8.1 21.7 29.3 7.9 4.8 5.0 2.8 37.2 27.5 20.5 14.1 7.1 36.8 1.8 41.4 13.8 1.2 12.4 8.7 4.0 0.5 9.1 8.9 6.3 24.2 20.7 7.9 50.1 31.5 8.6 10.1 0.2 0.9 6.5 7.2 58.7 2.0 2.0 2.4 11.3 1.1 0.5 5.2 1.0 1.9 1.5 0.9 1.0 0.9 0.0 3.0 1.2 16.2 5.3 0.6 1.3 0.4 31.0 7.1 0.0 23.4 3.1 0.6 0.2 0.6 1.0 4.9 5.3 0.4 6.9 0.1 2.6 9.6 97.9 1.4 14.7 0.2 0.3 4.7 0.1 18.1 1.6 0.0 32.3 3.8 0.6 14.9 1.1 6.8 10.2 29.7 3.2 8.0 0.3 1.6 3.4 2.2 4.3 5.6 67.8 89.6 0.7 2.0 0.1 2.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.3 0.0 21.7 33.5 24.0 28.9 21.7 29.3 37.2 27.5 41.4 24.2 31.5 58.7 1.1 0.0 0.6 0.0 5.2 0.0 0.0 0.0 0.0 0.0 9.2 10.3 0.0 0.0 1.3 0.0 0.0 2.9 10.2 0.0 0.0 1.7 0.0 49.5 13.9 0.7 0.0 0.0 0.0 2.0 2.0 2.0 0.0 39.6 2.5 4.5 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 14.3 0.0 0.0 1.3 8.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 4.2 7.8 7.1 0.0 0.0 XPNPEP2 ENSG00000122121 "X-prolyl aminopeptidase 2" O43895 X 129738949-129769536 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 166.6;kidney: 156.0" "Cell type enriched" "Detected in some" 6 "Proximal enterocytes: 475.9" "Cancer enhanced" "Detected in many" "liver cancer: 18.3" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 4.3;intermediate monocyte: 1.4;MAIT T-cell: 1.2;memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.8;naive CD8 T-cell: 2.0;non-classical monocyte: 2.8;T-reg: 1.4" "Group enriched" "Detected in many" 7 "monocytes: 2.8;T-cells: 4.3" "Cell line enhanced" "Detected in some" "ASC diff: 8.2;ASC TERT1: 40.1;HSkMC: 21.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA000339, CAB025136, CAB025269, HPA064568" Enhanced Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 13000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "CAB025136: , CAB025269: , HPA000339: AB_1858894, HPA064568: " "unprognostic (7.95e-2)" "unprognostic (5.73e-2)" "unprognostic (2.56e-1)" "unprognostic (6.21e-3)" "unprognostic (3.54e-2)" "unprognostic (1.54e-1)" "unprognostic (4.04e-1)" "unprognostic (3.26e-1)" "unprognostic (3.01e-1)" "unprognostic (2.41e-2)" "unprognostic (3.07e-1)" "unprognostic (9.28e-3)" "unprognostic (2.77e-2)" "unprognostic (6.53e-2)" "unprognostic (3.18e-2)" "unprognostic (1.39e-2)" "unprognostic (3.26e-3)" 7.5 0.9 0.1 3.7 0.1 0.2 3.0 0.1 0.1 3.7 0.1 5.5 99.0 2.4 0.1 2.2 6.3 4.3 5.3 0.1 0.1 156.0 23.1 2.1 0.5 0.2 0.1 1.8 0.3 0.3 0.1 1.2 0.1 1.8 6.3 0.0 1.5 0.4 0.5 4.4 166.6 6.0 0.1 0.3 3.4 0.1 0.1 1.0 1.4 2.4 0.4 7.8 4.0 0.1 0.0 0.0 0.5 0.0 8.2 40.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 0.0 0.0 21.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 4.3 1.4 1.2 0.0 1.3 2.8 0.2 0.2 0.4 2.0 0.1 0.0 2.8 0.4 1.4 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 1.2 0.0 0.0 0.0 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.8 0.0 0.2 0.5 11.4 5.9 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.2 0.0 0.0 10.0 1.1 0.0 0.0 0.0 0.4 18.5 0.8 0.0 0.3 12.8 0.0 1.0 3.6 0.0 0.0 1.0 1.8 1.0 0.0 0.0 3.1 0.0 0.1 0.0 21.0 0.0 0.1 0.0 475.9 75.1 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 1.0 1.2 0.9 0.0 8.4 0.0 ZC3H12B "CXorf32, MCPIP2" ENSG00000102053 "Zinc finger CCCH-type containing 12B" Q5HYM0 X 65366638-65507887 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 30 "Astrocytes: 90.4;Excitatory neurons: 232.1;Inhibitory neurons: 219.8;Microglial cells: 128.4;Oligodendrocyte precursor cells: 253.8;Oligodendrocytes: 258.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA000836 Uncertain Approved "Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Endoplasmic reticulum" "Golgi apparatus, Vesicles" "HPA000836: AB_2217374" "unprognostic (1.91e-1)" "unprognostic (9.72e-2)" "unprognostic (1.38e-1)" "unprognostic (1.71e-2)" "unprognostic (1.64e-1)" "unprognostic (7.44e-3)" "unprognostic (7.86e-3)" "unprognostic (5.46e-2)" "unprognostic (3.32e-1)" "unprognostic (5.76e-2)" "unprognostic (1.12e-3)" "unprognostic (1.28e-1)" "unprognostic (2.61e-1)" "unprognostic (1.11e-2)" "unprognostic (5.08e-2)" "unprognostic (1.45e-2)" "unprognostic (1.71e-2)" 0.6 0.5 2.4 0.4 2.7 0.2 0.5 2.1 2.7 1.3 0.8 1.3 0.6 1.3 0.5 0.3 1.3 0.6 0.6 2.7 1.6 0.7 0.5 0.5 0.5 1.1 1.4 1.7 0.4 1.6 2.2 0.0 0.9 1.1 0.6 1.9 0.6 1.1 0.2 0.3 0.9 0.9 1.3 0.4 0.8 0.2 2.1 0.9 1.0 0.3 0.3 1.0 0.9 2.3 0.1 0.2 2.1 0.3 0.0 0.0 0.2 0.5 1.1 0.0 0.3 0.2 0.2 0.3 0.1 0.6 0.0 0.3 0.5 0.0 0.0 0.3 1.5 0.7 1.2 0.3 0.0 0.6 0.1 0.1 0.0 0.0 0.0 0.4 0.0 1.7 0.4 1.7 0.0 0.0 0.9 0.2 0.8 1.2 0.4 1.0 0.1 0.4 0.0 0.1 0.0 1.0 0.0 0.0 0.0 1.2 0.0 0.5 0.0 0.0 0.4 0.7 0.2 0.3 0.4 0.7 1.3 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 2.4 2.7 2.1 2.7 2.7 1.6 1.1 1.4 0.9 1.3 2.1 2.3 0.2 6.4 0.5 90.4 1.3 0.0 0.5 0.0 1.2 2.7 0.1 0.6 0.6 0.0 0.0 0.0 2.1 0.0 0.1 0.7 0.0 0.2 0.2 0.7 1.3 0.5 4.2 0.0 232.1 0.2 0.2 1.4 0.0 0.1 0.0 0.6 0.7 0.7 0.1 1.7 219.8 1.3 0.0 0.0 0.3 0.2 2.5 0.0 0.0 128.4 0.1 1.0 0.0 253.8 258.0 0.2 0.6 4.1 0.3 0.3 1.0 0.4 0.0 1.5 0.0 2.1 1.1 0.0 0.1 0.1 0.4 0.0 0.4 0.5 1.0 0.1 ZFP36L1 "Berg36, BRF1, cMG1, ERF1, RNF162B, TIS11B" ENSG00000185650 "ZFP36 ring finger protein like 1" Q07352 14 68787660-68796253 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA transport, Transport" "Developmental protein, DNA-binding, Ribonucleoprotein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 1973.2;Squamous epithelial cells: 2019.8;Suprabasal keratinocytes: 3223.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 2901.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 2901.2" "Cell line enhanced" "Detected in all" "hTERT-HME1: 462.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001301 Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA001301: AB_1080644" "unprognostic (1.18e-2)" "unprognostic (2.64e-1)" "unprognostic (1.28e-1)" "unprognostic (1.58e-1)" "unprognostic (7.00e-2)" "unprognostic (1.27e-1)" "unprognostic (1.64e-2)" "unprognostic (1.11e-1)" "unprognostic (2.17e-2)" "unprognostic (3.81e-3)" "unprognostic (1.13e-3)" "unprognostic (1.30e-1)" "unprognostic (1.11e-2)" "unprognostic (6.45e-3)" "unprognostic (5.77e-2)" "unprognostic (2.97e-1)" "unprognostic (5.68e-2)" 342.7 107.9 108.1 218.2 108.3 84.0 305.6 118.0 96.1 466.4 91.7 335.1 127.5 423.1 107.7 293.0 303.3 174.9 178.8 98.7 184.1 157.8 260.1 242.7 199.5 207.8 187.5 453.5 225.4 161.7 67.3 315.8 145.0 222.3 104.2 57.5 319.3 201.7 93.1 511.3 151.5 316.0 162.7 178.5 196.9 49.3 142.6 130.1 190.6 89.6 150.4 335.8 467.0 166.8 235.6 211.8 94.7 139.0 234.4 187.2 203.9 96.4 169.6 59.1 72.9 93.9 159.5 58.4 59.5 177.4 85.5 108.4 8.8 313.8 70.0 27.9 13.2 21.5 115.0 68.2 133.8 3.3 24.3 157.6 396.4 69.1 462.1 195.2 119.2 17.1 61.5 113.7 314.4 54.1 9.3 11.1 78.7 105.1 31.7 150.5 127.1 17.8 213.4 155.3 1.0 2.5 113.7 163.4 87.8 131.9 148.3 3.0 254.4 167.3 122.8 139.0 101.0 62.9 32.9 39.9 213.5 1.4 66.9 230.8 240.9 3.9 211.1 244.7 197.2 266.0 168.8 150.3 123.8 461.4 179.3 162.2 2901.2 154.3 176.1 16.2 174.5 257.5 108.1 108.3 118.0 96.1 98.7 184.1 207.8 187.5 145.0 162.7 142.6 166.8 830.2 477.5 415.6 172.7 513.8 1333.5 761.2 830.2 1973.2 4.6 750.7 504.4 84.2 420.4 523.9 364.1 0.0 442.1 276.5 164.4 84.1 575.8 97.0 434.6 479.6 571.0 20.4 87.7 1.5 573.1 476.6 894.3 218.6 656.2 200.8 21.1 292.7 595.6 548.3 0.0 0.7 225.3 215.7 613.9 1272.8 72.2 502.0 670.0 528.3 142.4 499.0 211.9 131.8 63.8 0.9 544.8 138.3 397.2 191.7 657.7 138.4 143.7 314.5 9.2 269.5 562.0 714.4 12.2 13.3 2019.8 3223.6 898.7 405.2 157.1 191.1 817.8