Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABCG8 GBD4 ENSG00000143921 "ATP binding cassette subfamily G member 8" Q9H221 2 43831942-43882988 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 40 "intestine: 31.5;liver: 63.4" "Group enriched" "Detected in some" 4 "Hepatocytes: 32.0;Proximal enterocytes: 13.8" "Cancer enriched" "Detected in some" 30 "liver cancer: 21.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 44 "Hep G2: 5.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA019556 Uncertain Approved Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA019556: AB_1844444" "unprognostic (1.99e-1)" "unprognostic (4.49e-1)" "unprognostic (3.22e-1)" "unprognostic (1.37e-1)" "unprognostic (3.09e-2)" "unprognostic (2.43e-1)" "unprognostic (1.99e-3)" "unprognostic (1.27e-1)" "unprognostic (6.28e-1)" "unprognostic (6.14e-3)" "unprognostic (4.69e-1)" "unprognostic (1.76e-1)" "unprognostic (2.68e-1)" "unprognostic (7.86e-3)" "unprognostic (5.03e-1)" "unprognostic (1.50e-1)" 0.1 0.0 0.4 0.1 0.3 0.1 0.0 0.2 1.1 0.0 0.0 0.2 29.8 0.1 0.0 0.0 0.2 0.9 0.0 0.2 0.4 0.3 63.4 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.1 31.5 0.0 0.0 0.1 0.3 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 1.1 0.2 0.4 0.3 0.1 0.4 0.0 0.7 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 2.8 0.6 1.8 0.0 0.0 0.1 0.0 1.9 0.1 0.0 0.2 0.7 0.6 0.0 2.7 3.6 0.0 0.0 0.2 0.0 0.5 0.0 0.2 0.4 32.0 0.0 0.0 2.8 0.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 5.0 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.2 0.0 ACSL6 "ACS2, FACL6, KIAA0837, LACS2, LACS5" ENSG00000164398 "Acyl-CoA synthetase long chain family member 6" Q9UKU0 5 131949973-132012243 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.6;brain: 32.0;retina: 45.8;testis: 20.7" "Cell type enhanced" "Detected in many" "Astrocytes: 229.2;Cone photoreceptor cells: 229.4;Erythroid cells: 110.5;Inhibitory neurons: 110.6;Rod photoreceptor cells: 130.0" "Group enriched" "Detected in some" 6 "colorectal cancer: 1.8;glioma: 1.9;liver cancer: 0.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 5 "T-cells: 1.6" "Group enriched" "Detected in some" 5 "SCLC-21H: 7.6;U-937: 6.2" HPA040470 Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA040470: AB_10794033" "unprognostic (1.99e-2)" "unprognostic (1.94e-1)" "unprognostic (3.55e-3)" "unprognostic (5.89e-2)" "unprognostic (6.97e-2)" "unprognostic (1.92e-2)" "unprognostic (8.38e-3)" "unprognostic (5.84e-2)" "unprognostic (8.69e-2)" "unprognostic (7.57e-2)" "unprognostic (9.28e-4)" "unprognostic (8.69e-2)" "unprognostic (3.22e-2)" "unprognostic (6.24e-3)" "unprognostic (1.79e-1)" "unprognostic (6.44e-3)" "unprognostic (1.70e-1)" 0.2 4.2 14.8 1.4 18.3 22.6 0.2 26.3 32.0 0.1 1.2 0.5 4.7 0.1 0.5 0.3 0.2 0.3 1.4 18.6 12.8 1.9 2.0 0.3 2.4 22.2 18.2 0.0 1.1 11.3 4.2 0.6 18.9 0.3 0.3 45.8 0.3 18.0 2.3 0.1 2.4 0.1 13.8 1.1 0.6 20.7 25.0 0.6 0.4 1.4 1.0 0.2 0.1 14.3 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.1 0.0 0.0 0.4 0.0 0.0 1.5 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.4 0.1 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.4 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.2 6.2 0.3 0.0 0.0 0.0 0.4 0.0 1.1 0.0 0.7 1.6 0.0 0.0 1.1 0.5 0.0 0.3 0.0 0.0 0.0 0.3 14.8 18.3 26.3 32.0 18.6 12.8 22.2 18.2 18.9 13.8 25.0 14.3 0.6 25.6 29.2 229.2 1.4 1.9 1.5 0.0 2.2 65.2 2.1 0.4 0.0 1.5 16.1 1.8 229.4 0.3 3.3 0.6 7.9 0.6 43.7 0.3 0.1 3.9 2.4 110.5 70.6 0.2 0.1 4.2 0.0 0.2 10.1 0.2 1.8 8.4 0.1 21.9 110.6 1.8 0.0 1.0 15.9 7.9 0.3 6.4 0.0 15.9 0.9 24.5 0.0 41.7 9.8 0.3 1.6 1.9 0.8 1.1 1.8 0.4 8.1 130.0 0.0 2.3 1.1 45.3 1.7 0.1 1.3 0.3 15.3 0.1 0.4 1.3 ADGRF3 "GPR113, hGPCR37, PGR23" ENSG00000173567 "Adhesion G protein-coupled receptor F3" Q8IZF5 2 26308173-26346817 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in single" "Cell type enhanced" "Detected in some" "Astrocytes: 11.4;Early spermatids: 12.0;Late spermatids: 28.0;Microglial cells: 5.6;Oligodendrocytes: 6.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MOLT-4: 1.4;U-937: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA044500 Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" "Golgi apparatus" Cytosol "HPA044500: AB_10794290" "unprognostic (9.58e-3)" "unprognostic (2.13e-2)" "unprognostic (4.07e-1)" "unprognostic (1.36e-1)" "unprognostic (6.39e-2)" "unprognostic (6.68e-4)" "unprognostic (8.98e-3)" "unprognostic (1.14e-2)" "unprognostic (1.08e-1)" "unprognostic (1.59e-1)" "unprognostic (9.66e-4)" "unprognostic (2.29e-1)" "unprognostic (8.09e-2)" "unprognostic (3.53e-2)" "unprognostic (2.58e-1)" "unprognostic (4.08e-2)" "unprognostic (8.70e-5)" 0.1 0.1 0.5 0.4 0.3 0.4 0.0 1.0 0.6 0.0 0.5 0.1 0.5 0.1 0.0 0.2 0.1 0.1 0.0 0.4 0.4 0.8 0.1 0.1 0.5 0.6 0.3 0.2 0.8 0.0 0.1 0.1 0.4 0.1 0.1 0.1 0.7 0.0 0.0 0.1 0.1 0.0 0.3 0.3 0.2 0.5 0.4 0.4 0.2 0.0 0.1 0.1 0.1 0.4 0.1 0.0 0.1 0.5 0.0 0.1 0.8 0.1 0.0 0.0 0.1 0.2 0.0 1.0 0.6 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.2 0.3 0.7 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.3 0.0 0.0 1.4 0.4 0.9 0.0 0.0 0.8 0.7 0.3 0.0 1.1 0.8 0.4 0.0 0.3 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.3 0.1 0.7 0.7 1.2 0.0 1.4 0.1 0.0 0.0 0.4 0.2 0.1 0.1 0.3 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.5 0.3 1.0 0.6 0.4 0.4 0.6 0.3 0.4 0.3 0.4 0.4 0.4 0.0 0.0 11.4 1.3 0.0 0.3 0.0 0.0 0.9 0.3 0.4 0.7 0.0 0.0 0.0 2.1 0.1 0.8 0.0 0.0 0.1 12.0 0.9 1.1 0.2 0.0 0.0 3.4 0.0 0.1 0.2 0.5 0.8 0.0 0.2 0.0 0.2 0.1 1.7 4.1 0.1 0.0 0.0 0.0 28.0 0.0 0.5 0.0 5.6 0.3 0.2 0.0 3.0 6.3 0.1 0.0 0.0 2.7 0.1 0.4 0.1 0.0 1.2 0.0 0.2 0.3 1.5 0.4 0.1 0.0 0.1 0.9 0.2 0.2 0.1 ADGRV1 "DKFZp761P0710, FEB4, GPR98, KIAA0686, MASS1, USH2C, VLGR1" ENSG00000164199 "Adhesion G protein-coupled receptor V1" Q8WXG9 5 90529344-91164437 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "G-protein coupled receptor, Hydrolase, Receptor, Transducer" "Deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "adrenal gland: 533.0" "Cell type enriched" "Detected in many" 8 "Astrocytes: 2207.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 15.5;HAP1: 23.0;K-562: 9.8;NTERA-2: 11.6;SCLC-21H: 11.1;SuSa: 15.0;U-266/70: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067503 Approved Approved "Lipid droplets" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Lipid droplets" "HPA067503: AB_2685856" "unprognostic (1.29e-1)" "unprognostic (3.02e-1)" "unprognostic (3.69e-2)" "unprognostic (1.38e-1)" "unprognostic (4.01e-2)" "unprognostic (2.61e-1)" "unprognostic (3.76e-2)" "unprognostic (1.62e-3)" "unprognostic (1.48e-2)" "unprognostic (1.87e-1)" "unprognostic (3.95e-3)" "unprognostic (7.50e-3)" "unprognostic (9.73e-7)" "unprognostic (1.87e-2)" "unprognostic (5.24e-2)" "unprognostic (3.48e-2)" "unprognostic (7.14e-2)" 0.0 533.0 36.9 0.0 47.8 0.6 3.6 12.7 40.3 0.9 22.4 1.0 0.3 0.1 0.7 2.4 0.2 12.3 0.2 39.1 11.6 21.5 42.3 2.1 0.0 9.4 12.8 0.2 1.5 0.8 15.1 4.1 9.4 1.3 1.0 18.2 2.3 0.2 0.2 2.1 0.5 0.0 7.3 0.3 1.1 1.4 18.3 0.8 17.5 0.0 0.4 10.4 1.9 26.1 0.5 2.1 15.5 0.0 0.0 0.1 0.2 0.3 0.1 0.0 0.0 1.7 0.2 0.3 0.4 0.0 0.4 0.2 23.0 0.2 0.0 1.0 4.3 4.1 2.0 1.4 0.0 0.3 0.1 0.0 4.8 0.0 0.1 0.1 0.0 0.1 9.8 2.6 0.0 2.1 0.1 0.2 11.6 2.9 4.2 0.0 0.4 2.1 0.0 0.5 11.1 2.7 3.4 2.2 0.2 15.0 5.9 0.0 0.8 0.4 1.9 0.5 1.1 13.4 4.1 0.6 0.7 0.2 0.0 3.2 0.9 2.8 1.0 0.7 1.7 1.5 1.1 1.4 0.5 2.9 1.7 0.9 4.6 1.1 0.5 1.2 1.6 0.2 36.9 47.8 12.7 40.3 39.1 11.6 9.4 12.8 9.4 7.3 18.3 26.1 0.4 25.6 26.5 2207.3 0.0 0.0 6.1 0.0 1.8 28.0 15.5 7.4 2.4 2.8 5.6 5.5 264.8 3.0 0.4 0.6 1.9 1.9 43.5 3.3 0.3 1.1 7.3 0.0 54.0 4.2 2.6 1.1 4.6 1.9 0.0 6.7 0.0 12.4 0.2 10.1 21.9 0.4 0.0 0.8 0.0 54.8 0.6 0.5 0.0 51.5 1.2 8.9 1.0 40.2 7.4 1.7 1.2 0.4 0.1 2.1 0.1 24.2 7.3 84.4 0.0 0.3 0.4 3.6 4.5 2.9 0.0 4.1 0.6 0.2 1.2 9.0 CASR "FHH, GPRC2A, HHC, HHC1, NSHPT" ENSG00000036828 "Calcium sensing receptor" P41180 3 122183668-122291629 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "parathyroid gland: 654.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 25.6;Alveolar cells type 2: 20.2;Cholangiocytes: 27.1;Distal tubular cells: 13.7;Enteroendocrine cells: 11.5;Granulosa cells: 20.7;Respiratory ciliated cells: 15.3" "Cancer enriched" "Detected in some" 7 "pancreatic cancer: 5.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA039686, HPA050335" Enhanced NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 40: Granulosa cells - Unknown function" "HPA039686: AB_10673536, HPA050335: AB_2681092" "unprognostic (1.97e-2)" "unprognostic (7.40e-2)" "unprognostic (8.20e-4)" "unprognostic (3.15e-1)" "unprognostic (8.55e-4)" "unprognostic (1.58e-1)" "unprognostic (7.32e-2)" "unprognostic (7.67e-2)" "unprognostic (1.62e-1)" "unprognostic (1.48e-1)" "unprognostic (1.91e-5)" "unprognostic (2.72e-1)" "unprognostic (2.26e-1)" "unprognostic (1.24e-2)" 0.1 0.1 1.5 0.1 1.0 0.8 0.0 1.7 1.6 0.0 0.3 0.1 0.8 0.0 0.1 0.0 0.1 4.2 0.0 1.0 0.6 22.4 0.2 0.0 0.2 0.6 1.1 0.5 9.6 654.4 0.2 0.0 0.8 0.1 0.2 1.5 0.1 0.0 0.1 0.2 0.5 0.0 0.2 0.1 2.8 0.2 1.7 0.1 0.7 0.0 0.2 0.3 0.0 1.7 0.1 0.2 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.3 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.8 0.3 0.1 0.1 0.2 0.1 0.0 0.3 0.2 0.0 0.2 0.2 0.3 0.2 0.0 0.3 0.2 0.1 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.5 1.0 1.7 1.6 1.0 0.6 0.6 1.1 0.8 0.2 1.7 1.7 0.0 25.6 20.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 27.1 5.6 3.7 0.0 0.0 0.0 0.0 13.7 4.3 0.5 0.0 0.0 0.5 11.5 0.0 0.3 0.2 0.0 1.6 0.0 0.0 1.3 20.7 0.0 0.1 0.1 0.0 0.1 0.6 0.0 1.0 0.0 1.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.4 0.0 0.0 0.0 0.2 15.3 1.0 0.0 0.0 1.5 0.0 0.5 0.0 0.0 0.0 0.9 0.8 0.0 0.0 CEND1 "BM88, FLJ90066" ENSG00000184524 "Cell cycle exit and neuronal differentiation 1" Q8N111 11 787115-790113 "Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 234.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 94.2;Excitatory neurons: 42.9;Horizontal cells: 75.7;Inhibitory neurons: 45.6;Rod photoreceptor cells: 25.5" "Cancer enriched" "Detected in many" 13 "glioma: 24.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 13.6;Karpas-707: 31.0;SCLC-21H: 54.1;SH-SY5Y: 20.4;U-266/70: 21.1;U-87 MG: 28.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042527 Enhanced Supported Approved Mitochondria NA NA "Cluster 35: T-regs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" Mitochondria "HPA042527: AB_2678038" "unprognostic (4.62e-3)" "unprognostic (1.34e-4)" "unprognostic (9.66e-3)" "unprognostic (1.27e-2)" "prognostic unfavorable (4.38e-5)" "unprognostic (2.20e-3)" "unprognostic (4.11e-2)" "unprognostic (6.72e-2)" "unprognostic (2.60e-2)" "unprognostic (2.26e-1)" "unprognostic (2.00e-3)" "unprognostic (4.24e-3)" "unprognostic (1.94e-3)" "unprognostic (4.43e-2)" "unprognostic (1.71e-1)" "unprognostic (1.40e-1)" "unprognostic (1.03e-1)" 0.1 5.5 55.0 1.0 78.8 0.0 0.1 56.9 234.7 0.2 20.0 4.0 0.6 0.9 0.2 0.4 0.1 0.0 1.1 67.4 79.3 1.2 0.3 0.2 0.3 103.8 57.9 0.2 0.2 0.3 26.0 0.0 93.4 3.2 0.1 7.6 0.2 1.5 0.2 0.2 1.4 0.5 21.6 0.3 0.9 0.3 106.3 0.0 0.2 0.0 0.1 0.8 1.1 116.6 0.0 0.7 0.7 1.4 0.2 0.3 0.2 1.3 0.4 0.4 0.6 0.0 0.0 0.0 0.0 0.5 13.6 0.5 0.0 0.0 0.0 8.5 0.3 0.0 0.1 0.0 0.1 0.0 5.3 0.6 0.0 0.8 0.0 0.0 0.2 0.0 0.0 31.0 0.5 0.1 0.3 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 54.1 20.4 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.1 0.0 1.2 0.9 21.1 6.2 1.3 28.6 0.2 0.4 0.0 0.0 0.0 0.2 0.2 0.0 0.8 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 55.0 78.8 56.9 234.7 67.4 79.3 103.8 57.9 93.4 21.6 106.3 116.6 0.1 0.0 0.0 17.6 0.5 0.1 0.1 0.0 0.0 94.2 0.0 0.0 0.5 0.0 0.0 0.0 10.4 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.4 0.6 0.0 0.0 42.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.1 75.7 45.6 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 6.5 0.0 6.7 0.0 15.1 10.0 0.0 0.0 0.0 1.0 0.1 0.0 0.1 0.0 25.5 0.0 0.1 1.7 0.0 0.7 0.0 0.0 0.0 0.3 0.2 0.1 0.0 CHGB "SCG1, SgI" ENSG00000089199 "Chromogranin B" P05060 20 5911510-5925353 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "adrenal gland: 3466.0;pituitary gland: 1425.3" "Cell type enriched" "Detected in many" 5 "Enteroendocrine cells: 1036.1" "Cancer enriched" "Detected in many" 6 "pancreatic cancer: 154.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "SCLC-21H: 355.0;SH-SY5Y: 541.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008759, CAB009403, HPA012602" Enhanced Supported Enhanced Vesicles "Intracellular and membrane" NA NA 6500000 "Cluster 20: T-cells - T-cell receptor" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "CAB009403: AB_2081255, HPA008759: AB_1846704, HPA012602: AB_1846706" "unprognostic (1.79e-3)" "unprognostic (7.72e-2)" "unprognostic (3.48e-1)" "unprognostic (2.90e-2)" "unprognostic (1.68e-2)" "prognostic unfavorable (1.89e-4)" "unprognostic (7.96e-3)" "unprognostic (2.86e-1)" "unprognostic (6.18e-3)" "unprognostic (7.93e-2)" "prognostic favorable (9.96e-4)" "unprognostic (8.56e-2)" "unprognostic (8.21e-2)" "unprognostic (1.56e-1)" "unprognostic (2.81e-2)" "unprognostic (2.73e-1)" "unprognostic (1.01e-2)" 27.5 3466.0 17.1 5.3 9.9 0.8 2.1 134.2 90.9 0.6 0.0 7.9 60.2 1.6 4.2 0.6 13.7 0.4 71.9 101.9 92.2 8.3 0.7 2.4 3.1 76.5 100.2 25.8 92.8 6.4 1425.3 0.7 188.4 5.3 14.2 56.9 6.1 3.8 11.0 1.7 31.6 0.9 12.8 0.3 133.3 14.9 19.3 4.0 9.7 0.8 1.4 0.4 2.3 14.2 0.0 7.9 0.9 0.0 0.2 0.2 0.4 0.2 0.0 0.1 0.0 1.9 0.0 0.0 4.3 0.0 4.9 0.1 0.0 0.1 0.1 0.6 0.1 2.6 0.0 1.6 0.1 4.2 0.2 1.5 0.0 0.0 2.1 0.1 0.1 0.2 0.4 0.1 1.0 0.0 0.1 0.9 19.7 1.3 0.0 0.1 0.0 0.4 0.5 0.2 355.0 541.8 0.0 0.5 0.4 2.1 0.3 0.4 0.3 0.1 6.4 0.4 3.3 0.0 0.7 2.7 0.5 3.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 17.1 9.9 134.2 90.9 101.9 92.2 76.5 100.2 188.4 12.8 19.3 14.2 0.0 3.2 2.4 7.5 0.3 4.2 9.9 0.8 0.0 93.3 0.1 0.3 114.4 0.0 0.7 69.9 20.9 0.1 0.0 1.6 1.9 0.5 7.1 0.2 0.7 3.0 1036.1 0.0 31.6 0.4 0.0 18.9 4.1 0.3 0.0 202.8 0.0 0.3 0.1 75.7 28.8 61.9 65.1 0.3 9.5 8.3 0.9 1.6 7.2 9.4 1.1 13.7 1.0 7.5 5.2 22.9 17.7 0.4 0.0 3.3 3.2 0.3 4.4 75.6 13.1 3.0 1.6 76.6 41.8 0.0 3.7 0.3 1.0 3.0 2.2 4.2 CLCN5 "ClC-5, CLC5, DENTS, hCIC-K2, hClC-K2, NPHL1, NPHL2, XLRH, XRN" ENSG00000171365 "Chloride voltage-gated channel 5" P51795 X 49922596-50099235 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Antiport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "epididymis: 23.7;kidney: 46.2;liver: 16.9" "Cell type enriched" "Detected in many" 4 "Skeletal myocytes: 214.4" "Cancer enhanced" "Detected in all" "renal cancer: 9.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.6;plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in all" 4 "CACO-2: 49.0;RH-30: 66.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000401, HPA003213" Uncertain Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Plasma membrane" Cytosol "HPA000401: AB_1078531, HPA003213: AB_2666843" "unprognostic (3.33e-2)" "unprognostic (6.15e-2)" "unprognostic (3.13e-1)" "unprognostic (1.57e-1)" "unprognostic (7.59e-2)" "unprognostic (1.27e-1)" "unprognostic (1.54e-1)" "unprognostic (8.08e-3)" "unprognostic (1.60e-1)" "unprognostic (5.21e-2)" "prognostic favorable (5.20e-4)" "unprognostic (3.59e-2)" "prognostic favorable (2.05e-8)" "unprognostic (7.87e-3)" "unprognostic (1.07e-1)" "unprognostic (1.25e-1)" "unprognostic (3.60e-2)" 2.1 2.5 1.7 1.7 1.9 1.5 1.6 3.8 1.6 1.8 2.5 2.4 4.9 4.0 23.7 2.4 3.0 3.9 1.3 1.5 2.9 46.2 16.9 2.8 1.3 3.2 3.2 7.0 2.1 1.4 2.3 5.8 3.7 1.7 2.8 3.4 2.5 1.0 4.0 4.8 3.8 2.9 2.5 1.8 2.9 2.1 2.7 1.1 2.2 2.8 1.2 1.4 2.0 2.3 2.9 5.4 4.2 5.5 12.8 7.5 7.9 2.8 1.2 1.6 1.9 49.0 3.0 3.5 1.2 2.5 9.7 2.8 9.9 1.7 2.2 1.1 7.5 3.3 2.7 12.8 7.2 4.1 5.7 4.9 1.6 3.7 5.9 1.2 5.8 4.0 4.3 4.7 5.3 3.2 1.6 1.4 5.7 7.4 2.4 1.9 66.0 5.2 6.0 5.5 7.2 5.2 3.3 3.0 5.1 14.1 3.0 2.1 3.8 1.6 3.7 12.7 1.4 3.6 11.9 7.3 2.8 6.6 8.5 0.0 0.9 0.0 0.1 0.9 0.1 0.1 0.2 0.2 2.6 0.1 0.0 0.0 0.2 0.1 0.1 2.8 0.0 0.3 1.7 1.9 3.8 1.6 1.5 2.9 3.2 3.2 3.7 2.5 2.7 2.3 4.3 9.6 8.4 20.5 2.1 7.1 1.8 1.6 5.2 27.4 1.8 1.4 1.9 2.8 2.3 12.9 2.1 6.2 17.7 11.3 11.7 4.1 2.0 8.0 10.0 5.5 0.0 3.4 11.5 3.5 2.6 7.9 8.6 22.8 2.5 0.8 1.4 35.2 11.1 8.4 15.6 6.6 4.1 17.6 19.8 0.6 5.3 10.9 3.6 46.9 10.1 2.7 2.1 20.6 9.6 7.7 7.3 13.2 2.2 4.0 20.4 38.8 4.2 4.3 0.0 214.4 4.8 0.9 2.3 8.1 9.5 5.1 1.9 9.3 7.0 4.8 COL4A6 ENSG00000197565 "Collagen type IV alpha 6 chain" Q14031 X 108155607-108439497 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cell adhesion" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 32.6;urinary bladder: 40.7" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 24.5;Basal respiratory cells: 16.0;Cardiomyocytes: 13.1;Prostatic glandular cells: 12.1;Urothelial cells: 15.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 46.0;HeLa: 40.1;HHSteC: 59.2;hTERT-HME1: 44.1;HUVEC TERT2: 41.7;TIME: 94.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA065393 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Endoplasmic reticulum" "HPA065393: AB_2685483" "unprognostic (8.47e-3)" "unprognostic (4.50e-3)" "unprognostic (9.75e-3)" "unprognostic (9.80e-3)" "unprognostic (1.18e-1)" "unprognostic (5.99e-2)" "unprognostic (1.78e-2)" "unprognostic (3.78e-2)" "unprognostic (1.72e-1)" "unprognostic (9.84e-2)" "unprognostic (1.40e-2)" "unprognostic (4.11e-2)" "unprognostic (1.26e-1)" "unprognostic (1.32e-2)" "unprognostic (2.06e-1)" "unprognostic (8.54e-3)" "unprognostic (3.51e-1)" 3.0 0.5 0.3 0.4 0.3 0.0 2.0 0.2 0.2 12.6 1.3 1.9 1.4 32.6 17.0 5.5 14.9 13.3 5.4 0.3 0.7 4.2 0.1 1.0 0.1 0.9 1.7 9.3 0.1 5.5 7.2 3.2 1.0 12.5 2.1 1.2 1.4 21.5 1.4 6.5 1.5 24.5 0.4 1.4 13.3 1.2 0.3 0.9 0.7 1.2 0.1 40.7 9.2 0.6 0.1 31.1 9.9 0.0 24.2 1.7 0.0 0.0 1.8 0.3 0.2 17.9 0.0 0.0 0.0 0.0 3.9 5.8 10.3 46.0 0.8 0.4 8.8 0.8 40.1 0.3 59.2 0.0 0.0 2.6 27.8 6.5 44.1 0.1 41.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 14.0 0.0 3.8 0.0 0.0 0.0 1.9 3.4 0.0 0.0 2.4 0.0 0.0 18.2 0.9 0.0 94.2 0.0 0.1 5.5 0.1 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.2 0.3 0.7 0.9 1.7 1.0 0.4 0.3 0.6 0.1 0.0 0.0 6.2 0.0 6.4 24.5 16.0 3.4 0.2 2.3 6.1 13.1 0.0 2.6 1.8 0.0 0.1 0.0 0.0 1.9 0.0 2.1 0.7 6.0 0.4 0.0 0.0 0.4 0.0 0.0 6.2 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 2.0 0.0 0.3 0.3 4.1 0.0 0.0 8.4 0.0 5.5 0.0 0.0 0.6 0.1 0.0 9.1 0.0 12.1 0.0 0.0 2.2 0.4 0.0 0.4 7.2 0.2 0.2 0.1 3.7 0.0 0.1 0.8 0.0 15.2 CRB1 "LCA8, RP12" ENSG00000134376 "Crumbs cell polarity complex component 1" P82279 1 197268204-197478455 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 21.3;retina: 74.7" "Cell type enhanced" "Detected in some" "Astrocytes: 469.5;Cone photoreceptor cells: 164.7;Inhibitory neurons: 130.1;Muller glia cells: 79.7;Oligodendrocyte precursor cells: 280.0;Oligodendrocytes: 105.6;Rod photoreceptor cells: 149.3" "Cancer enriched" "Detected in single" 12 "glioma: 2.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "basophil: 7.7" "Lineage enriched" "Detected in single" 28 "granulocytes: 7.7" "Cell line enriched" "Detected in some" 8 "HeLa: 12.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA061250, HPA063127" Approved Uncertain Vesicles "Secreted in brain" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "HPA061250: AB_2684458, HPA063127: AB_2684944" "unprognostic (1.96e-1)" "unprognostic (5.38e-3)" "unprognostic (2.92e-3)" "unprognostic (1.50e-2)" "unprognostic (5.13e-1)" "unprognostic (3.28e-2)" "unprognostic (2.38e-1)" "unprognostic (2.49e-2)" "unprognostic (1.05e-1)" "unprognostic (1.48e-3)" "unprognostic (2.59e-1)" "unprognostic (2.01e-3)" "unprognostic (1.78e-3)" "unprognostic (1.56e-1)" "unprognostic (3.36e-2)" "unprognostic (2.96e-1)" 0.1 0.1 15.7 0.0 17.6 0.4 0.1 19.8 20.5 0.0 9.6 0.1 0.0 0.0 0.1 0.1 0.4 0.0 0.2 15.8 14.2 0.1 0.0 0.1 0.1 18.7 18.4 0.7 0.4 0.0 2.2 0.0 17.5 0.0 0.0 74.7 0.0 0.0 0.7 0.0 0.0 0.0 18.9 0.0 0.2 2.9 16.1 0.0 0.2 0.5 0.0 0.0 0.0 21.3 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 15.7 17.6 19.8 20.5 15.8 14.2 18.7 18.4 17.5 18.9 16.1 21.3 0.0 0.0 0.0 469.5 0.0 0.3 0.2 0.3 0.0 15.0 0.2 0.1 1.1 0.0 0.2 0.0 164.7 0.0 0.0 0.0 0.0 0.0 1.9 0.2 0.0 0.7 0.0 11.6 53.2 0.0 0.0 0.2 0.0 0.0 0.0 6.4 0.0 0.0 0.0 1.7 130.1 0.0 2.0 0.0 0.5 1.6 1.8 0.0 0.0 24.4 0.0 79.7 0.0 280.0 105.6 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.9 149.3 0.0 0.2 0.1 1.8 0.3 0.0 0.3 0.0 0.1 0.2 0.0 0.0 DNASE1 DNL1 ENSG00000213918 "Deoxyribonuclease 1" P24855 16 3611728-3680143 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Actin-binding, Endonuclease, Hydrolase, Nuclease" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 34.5;kidney: 34.2" "Cell type enriched" "Detected in many" 11 "Proximal enterocytes: 715.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA010703 Enhanced Supported Vesicles "Secreted in other tissues" NA NA 420000 "Cluster 49: Eosinophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA010703: AB_10600806" "unprognostic (5.18e-2)" "unprognostic (1.78e-2)" "unprognostic (1.16e-1)" "unprognostic (1.74e-1)" "unprognostic (2.38e-1)" "unprognostic (1.90e-2)" "unprognostic (3.73e-2)" "unprognostic (3.82e-1)" "unprognostic (3.20e-1)" "unprognostic (9.91e-2)" "unprognostic (1.69e-3)" "unprognostic (5.37e-2)" "unprognostic (1.37e-2)" "unprognostic (1.06e-1)" "unprognostic (1.74e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.14e-4)" 4.6 5.0 5.1 6.6 5.6 4.3 4.6 13.4 6.4 9.8 6.9 6.1 29.7 5.2 5.0 7.1 6.8 2.7 5.5 5.8 4.9 34.2 5.9 4.9 10.0 6.0 5.2 7.5 23.6 2.7 16.3 4.2 6.6 11.6 5.0 4.4 4.9 2.5 3.7 7.8 34.5 2.7 3.2 9.2 11.2 9.2 5.8 9.4 7.4 1.3 8.7 6.0 8.5 9.7 2.9 6.5 11.4 5.9 3.3 2.8 5.2 4.7 0.8 3.7 5.3 8.0 6.9 12.3 3.6 0.7 7.8 4.8 4.2 1.3 3.9 5.5 6.4 4.4 11.3 5.4 1.7 2.9 9.6 2.3 4.8 5.0 1.2 5.8 2.5 10.3 11.2 5.0 3.2 12.3 6.3 13.6 6.9 8.7 3.6 14.9 5.3 5.7 3.1 2.5 8.1 7.6 3.5 10.5 1.9 5.7 10.4 7.7 3.4 6.8 5.0 4.3 2.5 4.8 7.5 21.4 1.7 5.7 6.6 2.7 1.1 3.2 1.5 0.7 1.0 1.4 1.2 1.3 0.6 2.1 1.3 1.8 5.0 1.0 0.7 1.1 1.4 0.5 5.1 5.6 13.4 6.4 5.8 4.9 6.0 5.2 6.6 3.2 5.8 9.7 4.9 9.6 10.3 27.1 9.1 2.7 8.6 3.1 10.8 27.3 5.5 4.8 6.0 4.3 9.7 16.5 22.9 8.6 9.3 11.8 56.7 5.3 19.3 9.8 10.0 7.7 14.3 7.6 20.5 11.0 4.1 7.4 13.3 8.4 2.5 23.3 7.5 1.8 3.9 25.2 22.0 38.6 20.3 5.0 4.2 52.4 8.4 4.4 1.8 15.9 13.2 8.6 30.9 22.1 20.6 5.3 61.4 7.9 7.2 12.4 715.5 2.4 9.1 17.9 0.0 13.6 6.3 28.5 24.5 5.8 3.8 6.2 12.2 10.4 33.4 6.3 DUSP26 "DUSP24, MGC1136, NEAP" ENSG00000133878 "Dual specificity phosphatase 26" Q9BV47 8 33591330-33600023 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 421.3;tongue: 204.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 76.8;Cardiomyocytes: 59.4;Cone photoreceptor cells: 41.7;Enteroendocrine cells: 25.7;Horizontal cells: 25.2;Rod photoreceptor cells: 75.2" "Cancer enhanced" "Detected in some" "glioma: 6.7;pancreatic cancer: 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 97.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018221 Approved Supported Nucleoplasm NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "HPA018221: AB_2669813" "unprognostic (2.77e-4)" "unprognostic (2.70e-2)" "unprognostic (2.70e-3)" "unprognostic (5.47e-3)" "unprognostic (2.01e-1)" "unprognostic (1.24e-1)" "unprognostic (1.62e-1)" "unprognostic (2.53e-2)" "unprognostic (2.81e-1)" "unprognostic (1.39e-1)" "unprognostic (4.10e-3)" "unprognostic (1.78e-2)" "unprognostic (2.28e-1)" "unprognostic (1.52e-2)" "unprognostic (1.14e-1)" "unprognostic (8.15e-2)" "unprognostic (5.80e-2)" 0.7 27.4 44.2 1.2 45.2 0.2 0.4 47.4 49.6 1.2 18.4 2.8 3.5 1.3 5.6 5.0 3.6 1.2 70.8 45.0 53.0 1.5 0.2 3.3 0.4 39.8 42.1 33.2 3.0 2.0 61.4 0.0 55.2 4.2 1.1 34.1 4.6 0.8 421.3 0.3 2.6 2.7 38.3 0.7 3.9 3.6 44.4 0.8 0.9 204.4 0.8 1.2 1.7 41.1 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.1 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 97.7 23.1 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.1 0.1 3.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.2 45.2 47.4 49.6 45.0 53.0 39.8 42.1 55.2 38.3 44.4 41.1 0.0 0.0 0.0 1.3 0.9 0.0 0.2 0.0 0.6 76.8 0.0 0.3 59.4 0.0 0.0 0.0 41.7 0.0 0.0 0.0 21.5 0.4 7.8 0.4 0.1 0.8 25.7 0.0 11.3 0.4 0.0 3.5 0.5 0.1 0.0 1.0 0.4 0.0 0.0 25.2 14.7 0.5 0.0 0.0 0.0 5.2 0.0 0.1 1.8 2.8 0.0 22.8 0.0 12.1 12.0 1.1 0.0 6.0 5.3 0.3 0.0 2.5 0.0 75.2 0.0 10.8 5.2 0.2 0.2 0.0 0.0 0.0 0.6 0.7 0.1 0.1 FAM217A "C6orf146, MGC43581" ENSG00000145975 "Family with sequence similarity 217 member A" Q8IXS0 6 4049434-4087344 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 14.9" "Group enriched" "Detected in some" 15 "Early spermatids: 246.0;Late spermatids: 418.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA035455 Uncertain NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "HPA035455: AB_10669905" "unprognostic (5.93e-2)" "unprognostic (3.70e-2)" "unprognostic (1.24e-1)" "unprognostic (8.18e-2)" "unprognostic (1.54e-1)" "unprognostic (2.53e-2)" "unprognostic (2.99e-2)" "unprognostic (1.08e-2)" "unprognostic (2.09e-2)" "unprognostic (1.13e-1)" "unprognostic (1.85e-1)" "unprognostic (4.54e-1)" "unprognostic (6.55e-2)" "unprognostic (2.86e-1)" "unprognostic (1.85e-1)" "unprognostic (1.53e-2)" "unprognostic (5.51e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 246.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 418.8 2.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 20.9 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM222A "C12orf34, FLJ14721" ENSG00000139438 "Family with sequence similarity 222 member A" Q5U5X8 12 109713825-109770495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 33.3;Early spermatids: 29.1;Horizontal cells: 77.4;Oligodendrocytes: 78.5;Rod photoreceptor cells: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "SH-SY5Y: 116.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040181, HPA075616" Uncertain Approved "Golgi apparatus,Cell Junctions,Midbody ring" Yes NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus" "Cell Junctions, Midbody ring" "HPA040181: AB_10796448, HPA075616: " "unprognostic (8.59e-3)" "prognostic favorable (1.82e-5)" "unprognostic (1.43e-1)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (2.05e-2)" "unprognostic (1.46e-2)" "unprognostic (1.03e-1)" "unprognostic (6.66e-2)" "unprognostic (8.17e-2)" "prognostic favorable (4.81e-4)" "unprognostic (1.15e-1)" "unprognostic (4.16e-2)" "prognostic favorable (8.59e-4)" "unprognostic (3.93e-2)" "unprognostic (2.77e-1)" "unprognostic (1.24e-1)" 0.7 19.0 23.7 0.7 45.2 0.6 1.2 36.7 34.2 0.6 5.6 1.9 4.8 0.3 0.8 2.3 0.4 0.8 8.9 20.0 27.6 10.6 4.0 2.1 0.4 41.2 43.1 13.4 3.9 0.7 22.4 0.1 37.7 1.8 1.0 22.1 3.4 0.5 4.3 3.2 2.2 0.4 29.0 6.2 7.2 23.4 48.4 0.4 0.7 0.6 0.6 0.9 1.8 65.6 2.0 3.1 1.6 3.7 1.0 0.0 1.1 0.6 0.3 1.6 0.2 28.1 0.5 0.3 2.2 0.8 1.7 1.2 1.9 0.1 0.6 16.8 4.0 3.5 0.9 6.5 0.2 2.8 3.6 0.2 0.2 0.3 0.0 0.4 0.1 2.0 1.2 0.6 0.3 11.5 0.7 3.6 3.0 3.3 5.3 2.3 8.0 1.2 3.5 1.5 19.2 116.4 2.5 3.7 8.2 0.5 4.5 3.0 0.2 0.5 3.2 1.3 2.4 2.9 4.0 2.4 0.3 2.1 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 45.2 36.7 34.2 20.0 27.6 41.2 43.1 37.7 29.0 48.4 65.6 2.1 0.0 0.0 2.3 3.6 2.2 0.9 0.1 3.4 23.4 7.4 6.1 8.1 1.5 0.8 1.8 33.3 0.3 10.4 1.2 7.9 1.7 29.1 1.2 0.5 1.3 7.7 0.0 1.3 0.8 0.2 1.5 1.5 1.8 0.0 0.7 0.7 1.3 0.3 77.4 6.7 5.8 0.0 0.0 2.1 13.4 1.2 1.9 7.2 0.0 0.1 11.2 0.0 9.5 78.5 1.1 0.2 0.4 1.3 1.7 0.9 0.7 0.6 50.3 0.0 2.6 1.5 1.1 5.7 3.3 1.8 0.8 3.7 6.0 1.6 0.4 FLRT1 "MGC21624, SPG68" ENSG00000126500 "Fibronectin leucine rich transmembrane protein 1" 11 64103188-64119173 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 8.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.1;Excitatory neurons: 8.8;Inhibitory neurons: 16.1;Muller glia cells: 6.2;Oligodendrocyte precursor cells: 32.2;Oligodendrocytes: 13.2" "Cancer enhanced" "Detected in some" "glioma: 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 4.0;SCLC-21H: 5.4;SH-SY5Y: 13.5;THP-1: 11.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054589 Uncertain NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA054589: AB_2682533" "unprognostic (5.13e-3)" "unprognostic (1.55e-1)" "unprognostic (1.63e-1)" "unprognostic (8.65e-2)" "unprognostic (2.89e-1)" "unprognostic (9.55e-2)" "unprognostic (2.61e-3)" "unprognostic (6.95e-2)" "unprognostic (1.41e-2)" "unprognostic (2.98e-1)" "unprognostic (4.64e-3)" "unprognostic (6.02e-2)" "unprognostic (1.79e-1)" "unprognostic (2.62e-2)" "unprognostic (5.62e-2)" "unprognostic (1.29e-3)" "unprognostic (4.37e-2)" 0.3 4.4 7.0 0.3 8.4 0.0 0.4 1.6 6.8 2.9 0.0 3.9 0.5 1.5 0.0 0.8 0.6 0.5 1.2 7.1 3.0 2.5 0.9 0.2 0.0 1.5 4.3 0.5 1.0 0.0 1.2 0.1 0.6 1.2 0.3 1.6 0.7 0.9 0.2 1.0 0.9 0.5 1.6 0.3 1.1 0.3 8.5 0.0 2.2 0.1 0.0 0.7 1.1 7.4 0.4 0.7 2.7 0.2 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.2 0.3 0.0 0.0 0.0 0.4 0.4 0.0 1.1 0.6 3.7 0.0 0.0 0.7 0.2 0.0 0.9 0.1 0.0 2.1 0.3 4.0 0.0 0.5 0.1 0.6 1.2 0.1 0.2 0.8 0.2 0.1 0.0 0.3 5.4 13.5 0.3 0.3 0.4 0.0 0.4 11.3 0.1 0.3 1.2 0.0 0.1 0.0 0.0 0.0 0.2 3.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 8.4 1.6 6.8 7.1 3.0 1.5 4.3 0.6 1.6 8.5 7.4 0.0 0.0 0.0 4.2 0.0 0.1 0.0 0.0 0.0 6.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.0 8.8 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 6.2 0.0 32.2 13.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FRMPD2 "MGC35285, PDZD5C, PDZK5C" ENSG00000170324 "FERM and PDZ domain containing 2" Q68DX3 10 48153088-48274696 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.7;choroid plexus: 5.2;retina: 24.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 50.0;Cone photoreceptor cells: 287.7;Early spermatids: 97.7;Endometrial ciliated cells: 70.6;Late spermatids: 118.5;Respiratory ciliated cells: 62.9;Rod photoreceptor cells: 90.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.4;HBEC3-KT: 1.0;SCLC-21H: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 77: Retina - Visual perception" "Cluster 28: BEWO - Transcription regulation" "Cluster 9: Photoreceptor cells - Phototransduction" "unprognostic (1.53e-1)" "unprognostic (3.08e-1)" "unprognostic (7.88e-4)" "unprognostic (7.59e-2)" "unprognostic (2.37e-1)" "unprognostic (2.06e-1)" "unprognostic (6.54e-3)" "unprognostic (1.85e-1)" "unprognostic (6.60e-2)" "unprognostic (1.12e-1)" "unprognostic (3.25e-12)" "unprognostic (3.48e-2)" "unprognostic (5.43e-2)" "unprognostic (1.54e-1)" "unprognostic (7.43e-5)" 0.0 0.0 2.4 0.0 2.0 0.0 0.4 2.7 1.3 0.2 5.2 0.0 0.0 0.1 0.1 0.0 3.0 0.0 0.9 2.1 2.7 0.1 0.0 0.2 0.0 4.7 6.7 0.0 0.0 0.0 0.1 0.0 4.1 0.3 0.1 24.9 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.3 3.5 0.0 0.5 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.3 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 2.0 2.7 1.3 2.1 2.7 4.7 6.7 4.1 4.0 3.5 3.4 0.0 0.0 0.5 36.6 0.0 0.1 0.4 1.6 0.0 50.0 1.1 0.4 5.0 0.0 4.6 3.7 287.7 0.2 0.0 0.1 0.0 0.1 97.7 70.6 0.5 0.3 3.0 0.0 2.0 0.0 0.3 0.8 0.0 1.6 0.0 0.0 0.0 0.2 0.1 3.3 0.9 0.6 6.1 0.0 0.0 118.5 0.3 0.2 0.0 0.0 0.0 5.2 0.0 0.5 0.3 0.2 0.1 0.4 0.0 0.4 4.2 0.5 62.9 90.8 0.0 0.2 0.6 2.1 1.0 0.0 0.3 0.0 0.1 0.1 0.7 0.4 KCNJ1 "Kir1.1, ROMK1" ENSG00000151704 "Potassium inwardly rectifying channel subfamily J member 1" P48048 11 128836315-128867373 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Bartter syndrome, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 117 "kidney: 198.0" "Cell type enriched" "Detected in some" 5 "Distal tubular cells: 195.6" "Cancer enriched" "Detected in some" 7 "renal cancer: 3.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 39 "RPTEC TERT1: 116.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA026962 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA026962: AB_10601934" "unprognostic (1.75e-1)" "unprognostic (4.38e-2)" "unprognostic (1.14e-1)" "unprognostic (3.19e-1)" "unprognostic (7.55e-2)" "unprognostic (1.29e-1)" "unprognostic (3.01e-2)" "unprognostic (2.69e-1)" "unprognostic (1.46e-1)" "unprognostic (2.44e-2)" "unprognostic (6.47e-2)" "unprognostic (2.78e-1)" "unprognostic (6.05e-2)" "unprognostic (4.99e-2)" "unprognostic (1.61e-1)" "unprognostic (1.28e-1)" "unprognostic (7.81e-3)" 0.2 0.1 1.0 0.1 1.6 0.1 0.1 0.1 0.3 0.0 0.1 0.1 0.0 0.0 1.4 0.1 0.1 0.0 0.1 0.5 0.1 198.0 0.1 0.2 0.1 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 1.0 0.1 0.0 0.1 0.2 0.1 0.1 0.3 0.1 0.5 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 116.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 2.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.6 0.1 0.3 0.5 0.1 0.2 0.2 0.2 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 38.6 0.0 0.0 0.1 0.0 195.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 KCNJ3 "GIRK1, KGA, Kir3.1" ENSG00000162989 "Potassium inwardly rectifying channel subfamily J member 3" P48549 2 154697855-154858354 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.7" "Group enriched" "Detected in many" 5 "Excitatory neurons: 309.6;Horizontal cells: 124.5;Inhibitory neurons: 431.3" "Group enriched" "Detected in many" 5 "breast cancer: 12.2;renal cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 1.5;SH-SY5Y: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024231, HPA064138" Uncertain Approved "Plasma membrane,Mitochondria" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "Plasma membrane" "HPA024231: AB_1855558, HPA064138: " "unprognostic (1.45e-1)" "unprognostic (9.42e-2)" "unprognostic (2.66e-2)" "unprognostic (4.49e-4)" "unprognostic (8.89e-2)" "unprognostic (6.81e-2)" "unprognostic (7.24e-3)" "unprognostic (1.15e-2)" "unprognostic (4.25e-3)" "unprognostic (3.72e-3)" "unprognostic (3.33e-1)" "unprognostic (8.90e-3)" "unprognostic (3.75e-2)" "unprognostic (5.59e-1)" "unprognostic (2.32e-1)" "unprognostic (1.17e-1)" 0.5 1.4 5.7 0.1 8.7 0.1 0.3 32.7 17.0 1.6 4.7 0.8 10.7 0.1 1.1 0.1 0.4 1.3 15.1 14.6 3.7 10.5 3.1 0.2 0.0 2.2 4.3 0.1 2.1 10.4 6.8 0.0 2.4 6.5 0.8 5.0 0.0 11.3 5.3 0.1 9.5 0.2 1.6 0.4 0.7 0.4 4.1 0.0 0.1 0.2 0.0 0.4 0.6 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.4 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.3 0.3 0.2 0.1 0.1 0.1 5.7 8.7 32.7 17.0 14.6 3.7 2.2 4.3 2.4 1.6 4.1 6.4 0.3 0.0 0.0 38.8 0.0 0.8 5.3 0.0 0.0 10.9 3.7 1.7 49.0 5.7 0.0 20.2 14.6 0.0 0.0 0.1 5.9 0.1 0.3 0.0 0.0 1.3 31.1 0.0 309.6 3.2 0.0 5.4 0.0 0.0 0.0 0.0 0.0 1.3 0.1 124.5 431.3 7.0 0.0 0.0 2.1 0.0 6.2 0.6 1.8 5.6 0.0 0.7 0.0 32.6 6.8 0.0 1.2 4.1 0.0 6.1 16.2 8.7 0.0 3.9 0.0 8.0 1.6 0.4 0.3 0.0 1.8 0.0 0.8 1.9 8.4 4.7 KNG1 "BDK, BK, KNG" ENSG00000113889 "Kininogen 1" P01042 3 186717348-186744410 "Disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis, Inflammatory response" "Protease inhibitor, Thiol protease inhibitor, Vasoactive, Vasodilator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "liver: 3195.2" "Group enriched" "Detected in some" 25 "Distal tubular cells: 655.4;Hepatocytes: 1816.9" "Cancer enriched" "Detected in some" 126 "liver cancer: 608.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.6;Hep G2: 1.7;RH-30: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001616, HPA001645, CAB009809" Enhanced "Secreted to blood" NA NA 90000000000 47000000000 "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "CAB009809: AB_2134781, HPA001616: AB_1079216, HPA001645: AB_1079215" "unprognostic (3.88e-1)" "unprognostic (1.63e-1)" "unprognostic (2.82e-1)" "unprognostic (3.27e-1)" "unprognostic (8.30e-3)" "unprognostic (2.04e-1)" "prognostic favorable (1.28e-6)" "unprognostic (1.29e-2)" "unprognostic (1.10e-1)" "unprognostic (1.97e-2)" "unprognostic (9.96e-2)" "unprognostic (1.65e-1)" "unprognostic (3.45e-3)" "unprognostic (5.20e-2)" "unprognostic (2.46e-1)" "unprognostic (4.52e-2)" 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 464.1 3195.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.4 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.9 0.1 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.7 5.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 48.6 0.0 33.1 0.0 0.0 0.0 1.8 655.4 0.0 0.4 0.0 0.0 1.5 0.0 40.2 1.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 30.0 1816.9 0.1 0.0 0.8 0.1 0.0 47.2 0.0 0.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.0 0.5 0.1 1.1 0.0 0.0 0.0 0.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 2.7 0.0 0.1 0.1 MAP3K15 "ASK3, bA723P2.3, FLJ16518" ENSG00000180815 "Mitogen-activated protein kinase kinase kinase 15" Q6ZN16 X 19360056-19515261 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "adrenal gland: 10.8;choroid plexus: 13.1" "Cell type enhanced" "Detected in some" "Collecting duct cells: 5.5;Cone photoreceptor cells: 4.2;Granulosa cells: 7.5;Theca cells: 29.8" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.0;HAP1: 4.9;HEK 293: 4.1;JURKAT: 2.5;REH: 2.6;SuSa: 4.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA004006 Approved Vesicles NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Vesicles "HPA004006: AB_1079358" "unprognostic (2.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.21e-2)" "unprognostic (6.56e-8)" "unprognostic (3.47e-2)" "unprognostic (1.42e-2)" "unprognostic (2.19e-3)" "unprognostic (2.35e-2)" "unprognostic (1.46e-1)" "unprognostic (4.87e-2)" "unprognostic (1.30e-2)" "unprognostic (8.95e-2)" "unprognostic (2.77e-3)" "unprognostic (4.00e-1)" "unprognostic (2.37e-1)" "unprognostic (3.98e-2)" "unprognostic (8.20e-2)" 0.0 10.8 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.6 1.1 0.0 0.3 0.0 0.0 0.3 0.4 0.5 0.7 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.3 0.0 4.9 0.0 0.0 0.8 4.1 1.7 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.3 0.0 0.0 0.1 0.0 1.1 1.3 0.0 0.5 2.6 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.7 0.6 0.0 0.3 0.4 0.0 0.2 0.0 0.2 0.0 3.1 0.3 0.0 0.1 0.5 0.0 0.0 1.0 0.2 0.6 2.9 0.0 0.0 5.5 4.2 0.0 0.1 0.2 3.9 0.0 0.4 0.3 0.3 0.1 0.0 0.4 2.6 0.0 0.3 0.4 0.0 0.3 0.0 7.5 0.4 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.0 1.0 0.0 0.3 0.0 0.5 1.1 0.1 0.0 1.2 0.0 0.2 0.0 0.1 0.0 0.6 0.0 0.3 0.2 0.6 1.4 0.0 0.0 0.1 0.2 29.8 0.1 0.0 MFSD4A "DKFZp761N1114, FLJ25004, FLJ34577, MFSD4, UNQ3064" ENSG00000174514 "Major facilitator superfamily domain containing 4A" Q8N468 1 205568885-205602918 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 66.7;stomach 1: 132.6" "Cell type enhanced" "Detected in some" "Adipocytes: 11.3;Collecting duct cells: 9.2;Distal tubular cells: 13.7;Endometrial ciliated cells: 9.9;Glandular and luminal cells: 40.5;Proximal tubular cells: 7.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 17 "amygdala: 11.4;basal ganglia: 8.4;cerebral cortex: 18.4;hippocampal formation: 14.1;white matter: 5.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 1.5;SCLC-21H: 1.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 59.8" HPA055407 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "HPA055407: " "unprognostic (7.15e-4)" "prognostic favorable (7.54e-4)" "unprognostic (5.60e-2)" "unprognostic (1.38e-1)" "unprognostic (2.09e-1)" "unprognostic (1.56e-2)" "unprognostic (1.25e-1)" "prognostic favorable (4.59e-4)" "unprognostic (2.73e-2)" "unprognostic (1.65e-2)" "unprognostic (3.20e-2)" "unprognostic (6.97e-3)" "prognostic favorable (2.27e-13)" "unprognostic (1.58e-1)" "unprognostic (4.44e-2)" "unprognostic (5.75e-3)" "unprognostic (8.78e-2)" 2.2 0.4 11.4 1.1 8.4 0.0 2.7 0.6 18.4 8.5 0.0 13.8 1.9 1.0 9.2 1.4 2.5 16.8 0.9 14.1 0.0 66.7 0.2 6.8 0.4 0.0 0.0 0.6 1.4 0.4 1.5 6.2 0.0 1.4 18.2 14.0 17.1 0.6 0.3 5.1 1.4 0.8 0.0 0.6 132.6 0.5 0.0 0.6 0.4 0.7 1.3 0.7 0.8 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 8.4 0.6 18.4 14.1 0.0 0.0 0.0 0.0 0.0 0.0 5.3 11.3 6.4 2.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 3.8 2.9 0.0 0.0 6.2 9.2 0.0 0.5 0.7 0.0 13.7 1.4 0.0 9.9 6.0 2.5 0.0 0.0 0.0 6.2 0.1 0.5 0.0 40.5 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 7.7 2.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.8 0.2 0.0 0.0 MUC15 ENSG00000169550 "Mucin 15, cell surface associated" Q8N387 11 26559032-26572263 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "epididymis: 1949.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 109.0;Respiratory ciliated cells: 168.3;Syncytiotrophoblasts: 665.9" "Cancer enriched" "Detected in many" 11 "thyroid cancer: 56.7" "Region enriched" "Detected in single" 7 "basal ganglia: 4.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 8.9;K-562: 11.7;SK-BR-3: 18.0;SuSa: 12.0;U-266/70: 7.8;U-266/84: 21.1" "Group enriched" "Detected in some" 4 "cerebellum: 1.2;thalamus: 1.4" "Low region specificity" "Detected in many" "HPA026110, HPA073304" Enhanced "Intracellular and membrane" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 16: U-266 - Nucleosome" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA026110: AB_1854200, HPA073304: " "unprognostic (1.49e-1)" "unprognostic (2.08e-3)" "unprognostic (7.71e-5)" "unprognostic (5.09e-3)" "unprognostic (2.77e-2)" "unprognostic (3.04e-2)" "unprognostic (6.58e-2)" "unprognostic (1.12e-1)" "unprognostic (9.44e-3)" "unprognostic (1.98e-1)" "unprognostic (7.27e-3)" "unprognostic (4.96e-3)" "unprognostic (1.09e-1)" "unprognostic (5.70e-2)" "unprognostic (4.54e-3)" 0.1 0.3 0.4 0.0 4.5 0.0 15.4 0.0 0.6 6.5 1.1 0.0 0.0 0.4 1949.7 17.4 6.7 0.1 0.0 0.3 0.0 24.1 0.1 12.3 0.1 0.0 0.0 0.0 7.8 0.0 1.4 14.8 0.1 0.9 0.0 0.0 52.2 6.8 0.0 29.4 0.0 0.0 0.0 0.0 1.0 0.2 0.0 3.6 75.7 0.0 7.7 2.5 11.6 0.1 0.6 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 11.7 0.1 0.0 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.1 0.2 0.6 0.0 18.0 0.0 12.0 0.2 0.0 0.0 0.0 3.1 0.0 0.0 7.8 21.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.5 0.0 0.6 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 109.0 32.5 0.0 0.1 3.4 12.5 7.5 4.6 0.0 43.0 6.9 0.0 0.0 55.1 49.7 0.0 68.7 0.0 0.0 31.3 4.6 0.6 39.8 5.4 0.7 0.0 0.0 0.2 0.0 19.2 1.3 0.0 53.1 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 8.2 0.0 0.6 0.2 0.0 0.6 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.3 168.3 0.0 0.0 0.0 2.2 0.2 0.2 26.5 29.7 665.9 0.4 0.0 0.0 12.6 MYO3B ENSG00000071909 "Myosin IIIB" Q8WXR4 2 170178145-170655171 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Actin-binding, Kinase, Motor protein, Myosin, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 14.1;kidney: 5.3;parathyroid gland: 8.8;retina: 5.8" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 85.5;Early spermatids: 34.2;Inhibitory neurons: 18.3;Late spermatids: 29.6;Rod photoreceptor cells: 51.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HDLM-2: 11.2;HEL: 8.8;RT4: 11.7" "Region enriched" "Detected in some" 5 "basal ganglia: 5.2" "Not detected" "Not detected" HPA045483 Approved NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA045483: AB_2679344" "unprognostic (1.65e-1)" "unprognostic (7.87e-2)" "unprognostic (1.96e-2)" "unprognostic (1.43e-2)" "unprognostic (1.67e-1)" "unprognostic (7.15e-3)" "unprognostic (5.07e-2)" "unprognostic (2.61e-2)" "unprognostic (5.84e-3)" "unprognostic (2.12e-1)" "unprognostic (7.99e-3)" "unprognostic (2.59e-1)" "unprognostic (4.25e-5)" "unprognostic (2.34e-1)" "unprognostic (8.12e-3)" "unprognostic (1.18e-1)" "unprognostic (1.07e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 14.1 0.4 0.6 0.1 0.0 0.0 0.3 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 8.8 0.3 0.0 0.0 0.0 0.0 5.8 0.1 1.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.4 1.3 0.0 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 11.2 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 1.1 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.3 0.3 0.6 0.5 0.3 0.0 3.1 0.2 0.3 0.7 0.0 0.5 3.7 85.5 0.0 0.6 0.1 13.7 0.3 34.2 5.3 0.4 0.3 1.8 0.0 1.8 0.0 0.0 0.8 0.0 1.7 0.0 0.1 0.0 0.2 0.0 0.0 18.3 0.6 0.0 0.3 1.1 29.6 0.3 0.2 0.0 1.9 0.0 3.0 0.0 5.5 2.9 0.1 0.0 0.4 0.0 0.2 0.0 0.2 0.2 51.0 0.0 1.7 0.5 1.5 0.8 0.3 0.4 0.1 0.3 0.3 0.0 0.1 NDST3 HSST3 ENSG00000164100 "N-deacetylase and N-sulfotransferase 3" O95803 4 118033618-118258634 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Multifunctional enzyme, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 4.8;liver: 1.3;lymphoid tissue: 2.9;retina: 2.7" "Group enriched" "Detected in some" 5 "Excitatory neurons: 299.6;Inhibitory neurons: 128.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "MOLT-4: 17.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056189 Uncertain NA NA "Cluster 58: Brain - Synaptic function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA056189: AB_2683061" "unprognostic (1.95e-2)" "unprognostic (7.58e-2)" "unprognostic (4.34e-3)" "unprognostic (2.55e-7)" "unprognostic (4.05e-2)" "unprognostic (2.18e-2)" "unprognostic (2.86e-3)" "unprognostic (2.32e-2)" "unprognostic (1.87e-1)" "unprognostic (1.46e-2)" "unprognostic (7.43e-2)" "unprognostic (1.99e-2)" "unprognostic (1.09e-3)" "unprognostic (1.37e-1)" "unprognostic (4.39e-3)" "unprognostic (6.83e-2)" "unprognostic (8.85e-2)" 0.0 0.5 1.2 0.0 4.8 0.0 0.0 3.3 2.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.5 1.0 0.1 1.3 0.0 0.1 0.6 0.8 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.0 0.2 0.0 0.4 2.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.6 0.0 0.0 0.0 0.0 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 4.8 3.3 2.8 1.5 1.0 0.6 0.8 0.0 0.0 0.4 0.0 0.2 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 20.7 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 299.6 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.4 0.6 0.1 6.7 128.6 0.2 0.0 42.1 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.3 0.0 12.1 18.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 NEU4 ENSG00000204099 "Neuraminidase 4" Q8WWR8 2 241809065-241817413 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 75.8" "Cell type enhanced" "Detected in some" "Distal enterocytes: 74.6;Enteroendocrine cells: 34.4;Hepatocytes: 124.4;Intestinal goblet cells: 38.5;Oligodendrocyte precursor cells: 50.3;Paneth cells: 58.0;Proximal enterocytes: 76.0;Undifferentiated cells: 38.4" "Group enriched" "Detected in some" 7 "colorectal cancer: 2.3;glioma: 6.0;liver cancer: 6.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "Hep G2: 57.7;HMC-1: 32.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA037394 Enhanced NA NA "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA037394: AB_2675455" "unprognostic (1.50e-1)" "unprognostic (2.39e-3)" "unprognostic (1.85e-1)" "unprognostic (3.68e-4)" "unprognostic (3.76e-2)" "unprognostic (1.57e-1)" "unprognostic (8.70e-2)" "unprognostic (8.62e-2)" "unprognostic (1.74e-1)" "unprognostic (4.41e-2)" "unprognostic (1.52e-2)" "unprognostic (2.92e-1)" "unprognostic (8.11e-4)" "unprognostic (2.00e-2)" "unprognostic (3.82e-1)" "unprognostic (6.64e-3)" "unprognostic (1.55e-2)" 0.9 0.2 2.3 0.1 2.5 3.5 0.2 2.2 4.4 0.5 0.6 15.5 10.7 0.2 0.0 0.0 0.7 0.4 0.3 2.1 2.5 1.8 75.8 0.4 0.0 5.0 2.8 0.3 0.1 0.0 1.1 0.0 2.7 0.4 2.2 0.1 0.8 0.0 9.0 0.1 9.2 0.0 2.6 0.3 0.1 0.7 2.7 0.0 0.3 0.8 0.0 0.1 0.1 2.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 57.7 0.0 0.0 32.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 2.5 2.2 4.4 2.1 2.5 5.0 2.8 2.7 2.6 2.7 2.9 0.2 0.0 0.0 1.0 0.5 0.0 0.0 0.3 0.0 0.7 0.0 0.1 0.6 1.5 0.7 1.8 0.0 0.0 1.1 74.6 3.9 0.0 0.1 0.0 0.1 0.3 34.4 0.0 0.4 0.0 0.0 0.2 0.5 0.0 1.3 0.1 1.1 124.4 1.5 0.0 0.4 38.5 2.0 4.2 0.7 0.2 0.6 4.0 0.0 0.0 0.0 26.2 0.0 50.3 0.1 0.0 58.0 0.7 0.4 0.0 76.0 23.6 0.2 1.3 0.0 3.6 0.4 0.5 0.5 0.0 0.0 0.0 1.3 0.0 38.4 0.1 NHLRC4 ENSG00000257108 "NHL repeat containing 4" P0CG21 16 567005-569495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 11.7;kidney: 10.5" "Cell type enhanced" "Detected in some" "Collecting duct cells: 23.9;Endometrial ciliated cells: 23.3;Erythroid cells: 11.8;Leydig cells: 8.1;Respiratory ciliated cells: 18.1;Theca cells: 12.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 2.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 3.3;HMC-1: 9.6;REH: 2.6;RPMI-8226: 4.3" "Low region specificity" "Detected in single" HPA077301 Approved Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 3: HMC-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "HPA077301: " "unprognostic (7.95e-2)" "unprognostic (5.87e-2)" "unprognostic (4.28e-3)" "unprognostic (2.53e-2)" "unprognostic (1.08e-1)" "unprognostic (5.95e-3)" "unprognostic (2.21e-1)" "unprognostic (2.48e-1)" "unprognostic (2.28e-1)" "unprognostic (3.34e-1)" "unprognostic (2.20e-3)" "unprognostic (1.19e-2)" "unprognostic (1.16e-2)" "unprognostic (5.16e-3)" "unprognostic (1.25e-1)" "unprognostic (1.67e-2)" "unprognostic (1.60e-1)" 0.8 5.4 0.6 0.7 0.5 2.9 1.2 0.8 0.5 1.8 2.1 0.9 1.0 1.1 2.1 0.3 11.7 0.9 0.9 0.7 1.0 10.5 0.2 2.0 1.9 2.8 3.3 3.0 0.2 3.2 1.1 0.6 1.7 1.4 0.2 0.0 2.2 2.4 0.5 0.3 1.5 0.3 2.3 3.8 0.6 2.7 0.8 2.4 0.4 0.2 0.6 0.7 0.6 0.6 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.6 0.1 0.1 0.1 0.1 0.5 0.4 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.1 3.3 0.0 0.8 0.7 0.2 9.6 1.9 0.0 0.1 0.2 0.0 0.2 0.6 1.0 1.1 0.0 0.0 0.3 2.5 0.2 0.0 0.0 2.6 0.0 4.3 0.2 0.1 0.0 0.9 0.0 0.0 0.3 0.0 0.4 0.5 0.5 0.0 0.0 0.0 0.0 1.5 1.4 0.7 0.0 0.1 0.2 0.0 0.2 2.3 0.1 0.0 0.2 0.4 0.5 0.2 0.2 0.2 0.5 0.3 0.0 0.3 0.1 1.7 0.5 0.3 0.6 0.5 0.8 0.5 0.7 1.0 2.8 3.3 1.7 2.3 0.8 0.6 1.6 0.0 0.0 0.3 1.2 0.0 0.5 0.8 0.6 0.1 1.9 1.4 0.2 0.0 2.2 23.9 0.0 0.2 1.8 0.1 0.0 0.0 0.0 23.3 1.1 1.0 0.0 11.8 0.1 0.2 0.0 2.3 0.0 1.0 0.0 0.4 1.1 0.0 1.7 0.0 0.5 0.2 2.0 0.6 0.9 0.4 8.1 0.5 0.0 1.0 0.2 1.5 1.0 0.0 0.0 0.0 0.0 4.5 0.9 0.3 0.3 0.1 18.1 0.1 6.6 0.1 2.0 0.1 0.1 0.0 0.1 0.0 0.7 12.7 0.2 0.3 PCP2 "GPSM4, MGC41903" ENSG00000174788 "Purkinje cell protein 2" Q8IVA1 19 7631611-7633719 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 53.4;retina: 33.3;testis: 112.4" "Cell type enriched" "Detected in many" 4 "Late spermatids: 4139.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebellum: 53.4;white matter: 16.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 8.4;Karpas-707: 4.2;NB-4: 17.7" "Region enriched" "Detected in many" 44 "cerebellum: 2160.4" "Region enriched" "Detected in all" 28 "cerebellum: 552.9" HPA057428 Approved "Nuclear speckles,Vesicles" Yes NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear speckles" Vesicles "HPA057428: AB_2683436" "prognostic favorable (7.93e-4)" "unprognostic (6.06e-2)" "unprognostic (1.19e-2)" "unprognostic (4.43e-2)" "unprognostic (1.49e-1)" "unprognostic (1.79e-4)" "unprognostic (1.19e-1)" "unprognostic (4.88e-5)" "unprognostic (1.11e-1)" "unprognostic (6.23e-2)" "unprognostic (9.15e-3)" "unprognostic (6.01e-2)" "unprognostic (1.36e-2)" "unprognostic (8.17e-2)" "unprognostic (1.18e-1)" "unprognostic (8.70e-2)" "prognostic favorable (2.76e-5)" 0.4 1.6 0.4 1.1 0.6 3.7 5.5 53.4 2.3 2.1 0.0 0.6 1.4 0.9 3.3 2.0 2.4 2.3 2.2 0.5 0.0 8.0 3.7 2.2 3.0 0.1 3.5 0.1 5.4 1.1 1.4 0.4 5.5 5.9 0.3 33.3 16.3 1.9 0.2 7.0 1.6 0.0 0.1 3.0 3.1 112.4 0.0 3.1 5.7 0.0 1.4 0.9 1.6 16.8 1.8 0.4 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.7 1.6 0.7 1.1 0.0 0.0 1.3 0.0 0.2 0.0 0.8 0.6 2.6 2.8 0.1 0.0 0.3 8.4 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.2 4.2 0.0 0.3 0.3 17.7 0.4 0.3 0.0 0.8 0.2 0.7 0.8 0.1 0.1 0.0 1.4 1.4 0.0 0.4 3.7 3.4 0.2 0.0 0.5 0.4 0.0 1.4 0.7 0.2 0.0 2.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.1 0.1 0.1 0.2 0.3 0.2 0.3 0.8 0.2 0.0 0.6 0.0 1.7 0.4 0.6 53.4 2.3 0.5 0.0 0.1 3.5 5.5 0.1 0.0 16.8 0.1 0.0 2.3 0.0 0.2 0.8 1.1 1.4 0.0 734.7 7.7 5.8 0.0 2.8 1.8 5.5 22.9 0.2 2.7 0.7 9.8 0.8 836.5 1.0 0.1 2.6 0.0 0.0 0.0 0.2 0.1 0.1 0.0 1.5 1.3 1.3 0.0 0.5 0.4 23.5 0.0 0.4 0.0 0.8 1.3 4139.3 10.5 7.1 1.8 1.0 1.5 40.7 2.1 0.0 0.0 0.4 0.1 13.2 0.3 1.0 1.3 0.5 0.4 100.3 19.7 0.0 0.1 14.5 9.0 0.0 1.1 0.0 1.0 0.0 0.6 0.6 PROM2 ENSG00000155066 "Prominin 2" Q8N271 2 95274449-95291308 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 88.1;skin 1: 60.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 37.1;Club cells: 39.9;Collecting duct cells: 33.1;Squamous epithelial cells: 37.2;Urothelial cells: 37.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 79.5;CAPAN-2: 135.9;HaCaT: 73.2;hTCEpi: 78.4;MCF7: 62.1;RT4: 83.8;SK-BR-3: 117.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB046005, HPA063728" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Plasma membrane" "Cell Junctions" "CAB046005: AB_2284371, HPA063728: AB_2685104" "prognostic unfavorable (2.16e-4)" "unprognostic (1.60e-1)" "unprognostic (1.41e-1)" "unprognostic (1.86e-2)" "unprognostic (1.76e-1)" "unprognostic (7.30e-2)" "unprognostic (2.23e-1)" "unprognostic (1.70e-2)" "unprognostic (1.37e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.26e-1)" "prognostic unfavorable (1.55e-6)" "unprognostic (1.46e-2)" "unprognostic (4.59e-1)" "unprognostic (5.24e-2)" "unprognostic (2.50e-2)" 0.7 0.3 1.1 1.5 1.3 0.3 10.3 1.0 2.1 16.6 0.2 11.4 10.5 1.9 27.9 88.1 5.5 27.0 1.1 0.9 0.6 32.4 0.8 1.7 0.1 1.4 0.7 1.1 10.2 25.5 1.5 4.5 1.2 24.7 9.8 0.4 35.2 27.7 0.7 60.0 4.8 0.8 0.3 0.6 26.3 0.6 1.4 2.0 11.9 0.2 7.9 25.7 37.9 2.1 79.5 0.1 0.2 0.8 0.3 0.1 38.5 0.1 0.2 0.3 0.4 0.8 135.9 0.0 0.0 0.1 0.1 73.2 0.0 42.4 0.4 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.3 0.0 78.4 0.1 0.4 1.9 0.0 0.1 0.0 0.1 0.0 62.1 0.4 0.5 0.1 3.7 0.5 0.2 0.0 0.1 0.2 83.8 0.6 0.2 0.0 117.7 0.1 0.9 37.2 0.1 0.0 0.2 0.4 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.3 1.0 2.1 0.9 0.6 1.4 0.7 1.2 0.3 1.4 2.1 0.4 3.2 4.2 1.3 0.1 6.6 25.2 27.6 14.2 0.4 29.1 14.9 1.7 37.1 39.9 33.1 4.2 19.0 0.1 8.0 11.7 15.6 0.5 2.7 0.6 0.9 3.6 0.0 0.6 11.0 3.5 0.6 25.5 5.5 0.0 0.7 0.0 0.0 2.4 0.0 1.2 10.4 12.2 0.0 0.8 1.4 0.3 0.2 7.2 0.0 0.6 0.1 0.0 1.5 3.2 17.5 12.4 0.7 0.0 14.1 0.7 0.1 12.3 1.1 0.0 0.4 2.2 0.6 0.1 37.2 12.8 11.2 0.2 0.8 17.4 37.5 PRSS35 "C6orf158, dJ223E3.1, MGC46520" ENSG00000146250 "Serine protease 35" Q8N3Z0 6 83512534-83525704 "Enzymes, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 50.5" "Cell type enriched" "Detected in some" 36 "Muller glia cells: 410.9" "Group enriched" "Detected in some" 4 "glioma: 2.8;testis cancer: 4.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "MAIT T-cell: 19.5" "Lineage enriched" "Detected in single" 195 "T-cells: 19.5" "Cell line enhanced" "Detected in some" "BJ hTERT+: 10.4;CACO-2: 86.3;HAP1: 12.8;RPTEC TERT1: 24.6;SuSa: 17.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 2.9;cerebellum: 3.6;cerebral cortex: 5.8;hippocampal formation: 5.3;olfactory bulb: 2.7" "HPA038787, HPA038788" Uncertain "Secreted in female reproductive system" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 5: Muller glia cells - Visual perception" "HPA038787: AB_10675951, HPA038788: AB_2676208" "unprognostic (6.17e-2)" "unprognostic (8.75e-2)" "unprognostic (1.19e-2)" "unprognostic (2.63e-2)" "unprognostic (1.16e-1)" "unprognostic (4.03e-2)" "unprognostic (3.70e-4)" "unprognostic (6.08e-2)" "unprognostic (1.18e-3)" "unprognostic (2.33e-2)" "unprognostic (7.01e-2)" "unprognostic (9.07e-2)" "unprognostic (3.88e-6)" "unprognostic (7.15e-3)" "unprognostic (5.81e-2)" "unprognostic (2.82e-2)" "unprognostic (3.54e-4)" 1.3 2.4 2.9 0.1 3.8 0.0 0.3 1.7 6.8 2.9 1.5 0.1 0.3 1.3 1.1 0.3 1.4 4.2 4.4 3.2 2.1 3.1 0.4 1.3 0.7 1.8 1.9 10.2 0.3 0.3 1.1 3.6 1.8 1.1 0.3 50.5 0.3 0.4 0.1 0.2 0.1 1.5 1.8 0.7 0.3 3.1 2.6 0.1 0.4 0.1 0.1 1.3 0.5 2.2 0.0 0.5 1.9 0.0 0.1 0.0 0.0 0.3 10.4 1.0 2.0 86.3 0.0 0.0 0.1 0.4 0.0 0.0 12.8 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 3.1 0.0 1.2 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.1 1.6 0.4 8.2 0.0 0.0 0.0 24.6 0.0 0.0 1.0 0.0 0.0 0.0 17.9 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 19.5 0.0 0.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 3.8 1.7 6.8 3.2 2.1 1.8 1.9 1.8 1.8 2.6 2.2 0.3 3.2 0.5 8.1 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.1 1.5 0.0 0.0 1.8 0.0 0.3 0.0 0.1 9.8 0.1 0.1 0.0 0.3 0.8 1.8 0.0 0.2 0.0 0.0 4.4 0.0 0.0 0.0 0.9 0.0 0.3 0.4 6.7 0.2 0.0 0.0 0.0 0.0 0.2 1.2 0.1 0.0 1.0 0.0 410.9 0.0 1.0 0.1 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 11.4 6.6 0.1 3.7 0.1 0.5 0.0 0.0 0.1 0.7 5.1 0.0 0.0 RANBP3L FLJ25422 ENSG00000164188 "RAN binding protein 3 like" Q86VV4 5 36246913-36302114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.9;kidney: 24.6" "Cell type enriched" "Detected in some" 7 "Astrocytes: 355.9" "Group enriched" "Detected in some" 5 "breast cancer: 1.4;glioma: 3.7;prostate cancer: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "ASC diff: 12.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA037471, HPA037472, HPA061526" Approved Uncertain Nucleoplasm NA NA "Cluster 65: Brain - Ion transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA037471: AB_10671756, HPA037472: AB_2675489, HPA061526: AB_2684552" "unprognostic (1.19e-1)" "unprognostic (1.02e-1)" "unprognostic (1.27e-1)" "unprognostic (1.41e-3)" "unprognostic (5.52e-3)" "unprognostic (2.85e-1)" "unprognostic (2.35e-3)" "unprognostic (1.08e-2)" "unprognostic (9.56e-2)" "unprognostic (2.66e-1)" "unprognostic (2.81e-1)" "unprognostic (1.28e-1)" "unprognostic (3.76e-4)" "unprognostic (1.68e-2)" "unprognostic (9.13e-2)" "unprognostic (8.87e-3)" "unprognostic (5.71e-2)" 3.8 1.7 25.2 0.3 27.0 0.0 7.6 4.6 29.9 1.2 5.4 0.8 0.2 0.7 1.8 0.5 1.2 1.8 1.5 25.1 12.2 24.6 9.9 2.0 0.2 9.9 18.9 2.1 0.4 0.2 2.9 5.0 7.4 13.5 0.4 5.3 0.6 2.9 0.4 0.4 0.4 0.6 12.6 0.2 1.8 4.7 18.6 0.1 2.2 2.9 0.6 6.9 0.8 15.2 0.0 0.0 0.1 0.2 12.1 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.2 27.0 4.6 29.9 25.1 12.2 9.9 18.9 7.4 12.6 18.6 15.2 0.3 0.0 0.0 355.9 0.0 0.0 0.1 0.0 0.6 0.4 4.1 2.3 0.3 0.0 0.0 9.2 0.0 0.0 1.3 0.0 46.9 0.0 0.1 0.1 0.7 0.4 0.0 0.0 5.1 0.0 0.0 1.5 0.0 0.0 0.0 0.2 0.4 1.3 1.9 0.0 4.5 0.0 0.0 0.0 0.3 0.8 2.1 0.2 1.8 23.4 0.0 16.1 0.0 5.5 2.8 0.0 0.0 2.2 0.0 1.3 0.0 0.2 0.0 0.6 13.1 0.6 8.3 0.0 0.1 0.0 0.0 0.1 0.0 3.0 0.0 0.1 RBBP8NL "C20orf151, dJ908M14.3" ENSG00000130701 "RBBP8 N-terminal like" Q8NC74 20 62410237-62427539 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 9.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 51.2;Intestinal goblet cells: 58.0;Paneth cells: 54.5;Proximal enterocytes: 157.4;Undifferentiated cells: 26.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 18.6;CACO-2: 27.5;MCF7: 11.5;SK-BR-3: 12.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "unprognostic (8.99e-2)" "unprognostic (6.95e-3)" "unprognostic (2.71e-1)" "unprognostic (1.18e-1)" "unprognostic (1.86e-2)" "unprognostic (1.27e-3)" "unprognostic (2.07e-1)" "unprognostic (1.26e-1)" "unprognostic (1.38e-1)" "unprognostic (2.76e-1)" "unprognostic (2.15e-1)" "unprognostic (1.44e-1)" "unprognostic (7.65e-3)" "prognostic favorable (6.91e-4)" 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.3 1.5 0.0 1.7 4.5 0.1 0.7 9.1 0.7 0.5 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 2.1 1.9 2.0 0.4 0.0 3.8 0.6 0.0 4.4 1.0 0.0 4.7 4.7 0.0 0.0 0.0 2.7 2.9 0.0 0.0 3.6 0.0 0.3 1.7 3.6 0.0 1.9 0.0 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 0.0 27.5 2.8 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.1 0.0 4.5 0.0 0.0 0.0 12.5 0.0 0.1 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.3 1.3 0.3 0.0 0.0 3.3 2.2 2.7 7.2 1.7 1.8 0.0 6.0 0.0 51.2 0.0 0.3 13.4 1.0 0.0 0.0 9.6 0.0 0.4 0.2 5.1 0.2 2.0 1.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 58.0 2.0 0.0 0.0 7.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 54.5 0.0 0.0 0.7 157.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 2.1 1.4 2.6 0.1 0.0 26.2 1.0 SEMA6D "FLJ11598, KIAA1479" ENSG00000137872 "Semaphorin 6D" Q8NFY4 15 47184101-47774228 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.5;placenta: 43.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 114.7;Excitatory neurons: 120.7;Horizontal cells: 79.1;Inhibitory neurons: 319.5;Oligodendrocytes: 140.1" "Cancer enriched" "Detected in many" 4 "glioma: 8.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 14.9;SCLC-21H: 13.3;SH-SY5Y: 12.1;SuSa: 14.2;U-266/70: 10.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043109 Approved "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA 1100000 "Cluster 45: Intestine - Brush border" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Golgi apparatus" "HPA043109: AB_10793941" "unprognostic (2.00e-1)" "unprognostic (4.62e-2)" "unprognostic (3.10e-2)" "unprognostic (3.83e-3)" "unprognostic (1.38e-1)" "unprognostic (3.85e-2)" "unprognostic (1.98e-1)" "unprognostic (2.17e-3)" "unprognostic (1.24e-1)" "unprognostic (5.36e-2)" "unprognostic (7.96e-4)" "unprognostic (1.42e-1)" "prognostic favorable (5.96e-5)" "unprognostic (3.74e-2)" "unprognostic (8.56e-2)" "unprognostic (3.30e-3)" "unprognostic (2.39e-4)" 5.5 1.5 11.3 3.9 27.9 0.4 5.0 11.1 21.3 5.8 0.0 10.6 21.8 1.6 2.5 1.7 4.9 4.0 9.4 9.8 16.3 15.1 3.1 8.9 2.1 17.2 31.1 26.7 16.1 10.6 5.5 43.1 23.1 4.5 12.7 15.8 4.5 8.4 20.9 3.0 38.5 3.3 12.0 2.5 3.0 2.6 20.5 2.7 5.8 6.0 0.6 3.1 10.0 28.8 0.0 0.0 2.5 0.0 1.5 1.2 0.2 0.6 14.9 0.4 0.0 0.3 0.1 2.2 0.0 4.0 0.0 7.6 3.4 1.1 0.1 1.1 1.7 0.0 5.0 0.0 4.0 0.0 0.2 1.1 8.3 0.0 0.5 0.0 1.0 5.7 0.1 3.4 0.4 0.8 2.8 0.7 4.6 0.0 0.0 1.6 0.1 2.4 1.1 1.1 13.3 12.1 0.1 1.0 4.3 14.2 0.5 0.0 0.0 6.9 0.3 0.2 0.0 10.0 0.0 2.3 1.8 0.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 11.3 27.9 11.1 21.3 9.8 16.3 17.2 31.1 23.1 12.0 20.5 28.8 13.9 51.3 1.5 72.8 0.2 2.0 4.0 1.4 1.2 6.2 0.5 10.7 10.0 4.3 2.1 11.0 114.7 19.7 0.1 40.6 5.9 1.0 0.2 0.5 2.3 10.1 17.4 0.0 120.7 0.2 1.8 10.8 0.0 0.3 3.8 71.0 5.0 0.9 2.6 79.1 319.5 5.4 0.0 0.0 1.9 1.2 23.3 1.0 8.8 15.9 0.0 9.3 0.0 43.2 140.1 0.3 8.5 13.5 0.0 1.2 53.5 0.2 0.1 2.3 0.0 9.3 13.9 0.8 6.3 0.3 1.1 4.7 0.2 3.4 15.1 1.6 SHCBP1 "FLJ22009, PAL" ENSG00000171241 "SHC binding and spindle associated 1" Q8NEM2 16 46578591-46621379 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.4;lymphoid tissue: 10.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 36.2;Extravillous trophoblasts: 28.7;Plasma cells: 38.3;Spermatocytes: 33.7;Spermatogonia: 23.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA048876 Uncertain Approved "Nuclear bodies,Microtubules,Midbody,Mitotic spindle" Yes Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies" "Microtubules, Midbody, Mitotic spindle" "HPA048876: AB_2680542" "unprognostic (2.44e-3)" "unprognostic (1.13e-1)" "unprognostic (2.98e-2)" "unprognostic (2.74e-1)" "unprognostic (2.54e-2)" "unprognostic (2.35e-2)" "unprognostic (2.96e-4)" "unprognostic (2.26e-3)" "unprognostic (5.35e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (4.47e-5)" "unprognostic (4.81e-2)" "unprognostic (2.22e-16)" "unprognostic (3.59e-2)" "unprognostic (3.86e-2)" "unprognostic (2.66e-1)" "unprognostic (2.66e-1)" 0.7 0.5 0.5 5.1 0.5 17.4 0.9 1.2 0.6 0.6 0.4 1.9 1.2 0.6 0.6 3.5 0.2 0.6 1.0 0.4 0.2 5.4 0.2 1.0 9.8 0.4 0.3 0.3 0.2 0.2 0.2 2.4 0.4 0.3 2.2 0.2 0.8 0.2 1.5 3.3 1.5 1.7 0.1 4.4 0.9 5.2 0.5 8.8 0.3 0.2 10.6 1.2 1.2 0.7 33.8 30.8 11.9 15.3 3.1 6.2 16.2 60.7 24.6 59.2 26.8 14.6 20.8 28.0 30.2 28.8 26.8 21.0 29.3 21.7 73.8 17.7 17.2 28.2 25.8 30.3 0.1 28.5 35.4 1.2 1.6 45.9 18.1 5.9 33.0 14.9 12.7 28.3 69.7 21.5 24.0 23.7 10.0 17.2 31.6 45.4 89.9 44.8 13.7 9.4 5.0 7.2 46.0 23.7 11.1 11.4 13.0 23.4 16.1 43.9 28.7 43.5 54.0 24.9 36.7 46.7 21.4 31.3 45.8 0.2 0.3 0.6 0.2 0.5 0.0 1.7 0.3 0.1 0.3 1.2 0.0 0.1 0.4 0.1 2.4 0.7 1.2 1.1 0.5 0.5 1.2 0.6 0.4 0.2 0.4 0.3 0.4 0.1 0.5 0.7 0.2 0.0 1.1 1.3 7.1 1.7 0.7 1.2 0.0 0.3 0.6 1.1 1.9 1.5 1.4 0.0 0.0 11.3 0.8 1.9 0.0 0.2 8.4 0.7 1.7 1.7 0.0 36.2 2.1 0.0 28.7 3.7 4.1 1.5 0.0 7.6 1.8 0.3 12.6 0.0 0.7 2.2 2.0 4.5 3.3 2.3 0.6 4.0 1.8 2.8 2.8 0.8 0.0 1.0 0.5 0.1 0.1 0.4 38.3 0.5 0.4 0.1 0.1 0.3 0.0 0.5 6.3 33.7 23.7 3.6 0.6 3.7 2.2 0.8 3.4 1.1 SIAH3 FLJ39203 ENSG00000215475 "Siah E3 ubiquitin protein ligase family member 3" Q8IW03 13 45777242-45851753 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.0;fallopian tube: 3.1" "Group enriched" "Detected in some" 5 "Endometrial ciliated cells: 28.6;Inhibitory neurons: 35.6" "Cancer enhanced" "Detected in some" "endometrial cancer: 0.5;ovarian cancer: 0.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "EFO-21: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA060576 Uncertain Supported Nucleoplasm,Mitochondria NA NA "Cluster 21: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria Nucleoplasm "HPA060576: AB_2684325" "unprognostic (1.07e-3)" "unprognostic (1.26e-1)" "unprognostic (3.00e-2)" "unprognostic (1.14e-1)" "unprognostic (4.96e-2)" "unprognostic (1.00e-2)" "unprognostic (1.05e-1)" "unprognostic (7.53e-2)" "unprognostic (3.24e-4)" "unprognostic (1.11e-1)" "unprognostic (4.77e-3)" "unprognostic (3.24e-3)" "unprognostic (9.03e-4)" "unprognostic (2.03e-1)" "unprognostic (2.18e-1)" 0.0 0.2 0.7 0.1 0.9 0.1 0.0 2.3 0.8 0.9 0.0 0.0 0.0 0.3 0.3 0.0 3.1 0.0 0.0 0.6 0.7 0.6 0.0 0.0 0.0 0.8 3.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.2 0.3 0.7 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 2.3 0.8 0.6 0.7 0.8 3.0 0.8 0.6 0.4 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.5 0.0 0.0 1.8 2.1 0.0 0.0 0.0 1.9 0.0 0.0 28.6 0.5 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 3.5 0.0 0.1 0.0 0.0 0.0 0.0 35.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.6 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 SIM2 "bHLHe15, MGC119447, SIM" ENSG00000159263 "SIM bHLH transcription factor 2" Q14190 21 36699115-36749917 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 31.1;kidney: 61.3" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 100.7;Squamous epithelial cells: 68.3" "Cancer enhanced" "Detected in many" "prostate cancer: 11.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 24.9;PC-3: 43.0;RPTEC TERT1: 54.3;RT4: 33.5" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hypothalamus: 1.2" HPA029295 Approved Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nuclear bodies" "HPA029295: AB_10610425" "unprognostic (1.17e-3)" "unprognostic (6.46e-2)" "unprognostic (5.03e-2)" "prognostic unfavorable (2.10e-4)" "unprognostic (8.62e-2)" "unprognostic (1.43e-2)" "unprognostic (8.30e-2)" "unprognostic (5.46e-3)" "unprognostic (1.65e-2)" "unprognostic (1.09e-1)" "unprognostic (5.16e-3)" "unprognostic (9.18e-2)" "unprognostic (9.18e-7)" "unprognostic (2.98e-2)" "unprognostic (3.79e-2)" "unprognostic (1.07e-2)" "prognostic favorable (2.88e-4)" 0.3 0.3 1.8 0.0 1.1 0.0 0.4 0.7 1.4 2.3 0.4 0.5 0.0 0.5 0.8 31.1 0.6 0.0 0.2 1.5 2.5 61.3 0.4 0.2 0.0 0.7 1.4 0.2 0.3 1.8 1.6 0.0 0.5 6.6 0.0 0.0 0.6 0.0 10.6 0.5 0.3 0.0 0.5 0.3 9.5 0.4 2.4 0.0 0.4 0.0 3.5 0.7 0.7 0.7 6.4 9.6 0.0 0.3 0.0 0.0 9.4 0.0 0.0 0.9 0.0 5.0 14.7 0.0 8.6 0.2 17.0 3.2 4.8 0.0 0.5 7.8 15.0 0.0 14.3 0.3 0.0 0.0 0.0 1.6 1.4 0.0 2.6 24.9 0.0 0.0 0.0 0.0 16.0 3.7 0.0 0.0 0.0 6.4 43.0 0.0 0.0 0.0 54.3 33.5 0.4 0.0 15.7 0.0 0.9 1.6 4.1 0.0 0.6 0.0 2.5 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.1 0.7 1.4 1.5 2.5 0.7 1.4 0.5 0.5 2.4 0.7 0.2 0.0 0.0 0.0 0.0 0.3 19.1 0.0 100.7 0.2 0.1 0.1 2.0 0.0 0.0 9.2 0.0 0.0 0.0 0.2 9.8 0.1 2.2 0.3 0.3 0.4 0.0 0.0 0.3 0.0 0.0 0.8 12.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 5.8 0.3 0.3 0.0 0.0 0.0 0.0 0.0 7.1 1.1 0.0 0.0 0.0 1.3 9.5 0.1 0.2 0.0 0.5 0.0 1.5 0.9 0.5 0.2 68.3 0.4 0.0 0.4 0.0 0.2 4.0 SLC5A1 "D22S675, NAGT, SGLT1" ENSG00000100170 "Solute carrier family 5 member 1" P13866 22 32043261-32113029 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sugar transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 528.1" "Cell type enriched" "Detected in many" 6 "Proximal enterocytes: 768.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "OE19: 34.2" "Region enriched" "Detected in single" 26 "cerebellum: 7.6" "Low region specificity" "Detected in many" "CAB015467, HPA051805, HPA055106" Enhanced Approved "Nucleoplasm,Nuclear membrane,Golgi apparatus,Cytosol" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Golgi apparatus" "Nuclear membrane, Cytosol" "CAB015467: , HPA051805: AB_2681618, HPA055106: AB_2682695" "unprognostic (1.96e-1)" "unprognostic (1.04e-1)" "unprognostic (2.24e-2)" "prognostic favorable (2.59e-4)" "unprognostic (3.85e-2)" "unprognostic (2.75e-2)" "unprognostic (1.60e-2)" "unprognostic (2.15e-1)" "unprognostic (9.22e-2)" "unprognostic (4.83e-2)" "unprognostic (6.21e-2)" "unprognostic (9.53e-2)" "prognostic favorable (6.97e-7)" "unprognostic (4.68e-3)" "unprognostic (1.98e-1)" "unprognostic (6.00e-2)" "unprognostic (1.45e-2)" 0.1 0.0 0.1 4.2 0.1 0.0 9.7 0.2 0.1 12.3 0.0 10.7 528.1 0.5 3.5 5.1 1.1 26.9 75.2 0.1 0.0 6.6 1.7 2.1 0.3 0.1 0.0 0.0 1.6 0.3 1.0 0.0 0.1 3.0 9.7 0.2 19.0 2.4 0.3 13.5 302.4 0.7 0.0 2.9 7.2 2.3 0.5 0.1 0.0 0.0 4.0 0.0 6.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.6 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 34.2 0.0 0.0 0.0 2.1 0.0 0.0 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.5 0.2 0.1 0.0 0.0 0.3 0.2 0.6 1.7 4.2 0.0 0.0 11.6 6.5 115.2 115.8 8.2 0.0 0.0 0.0 0.2 19.8 0.0 3.0 38.4 2.4 1.4 1.0 25.4 0.0 0.4 1.4 0.0 1.4 5.6 10.3 0.0 0.0 0.0 0.3 0.0 0.0 0.3 34.1 0.0 0.0 0.0 71.3 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 32.6 1.5 0.0 17.6 768.7 6.4 2.0 0.0 0.0 0.0 0.7 10.1 4.2 2.0 5.5 0.0 0.1 0.1 41.2 6.7 SLC9A3 NHE3 ENSG00000066230 "Solute carrier family 9 member A3" P48764 5 470456-524449 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 45.4;intestine: 94.3;kidney: 62.5;stomach 1: 50.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 16.0;Collecting duct cells: 16.5;Proximal tubular cells: 40.7" "Cancer enhanced" "Detected in many" "stomach cancer: 14.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HDLM-2: 37.8" "Region enriched" "Detected in single" 14 "cerebellum: 4.1" "Low region specificity" "Detected in many" "HPA036493, HPA036669" Enhanced Supported "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA036493: AB_10673353, HPA036669: AB_10670843" "unprognostic (1.27e-1)" "unprognostic (4.88e-1)" "unprognostic (9.35e-3)" "unprognostic (1.11e-1)" "unprognostic (2.37e-1)" "unprognostic (3.35e-1)" "unprognostic (2.51e-1)" "unprognostic (9.40e-2)" "prognostic unfavorable (8.49e-4)" "unprognostic (5.18e-2)" "unprognostic (1.29e-1)" "unprognostic (3.69e-2)" "unprognostic (3.84e-1)" "unprognostic (1.30e-1)" "unprognostic (1.04e-1)" "unprognostic (1.24e-2)" "unprognostic (1.32e-1)" 2.9 4.4 3.0 10.4 2.5 1.9 3.1 6.1 5.0 3.8 1.7 94.3 46.0 2.9 4.0 8.7 4.9 45.4 3.2 4.7 2.5 62.5 2.4 2.8 3.8 3.8 2.3 4.3 6.7 6.2 0.7 2.1 3.7 7.3 10.8 1.7 9.9 3.8 6.2 19.0 68.1 3.3 1.3 3.7 50.1 5.8 3.4 3.5 4.9 3.9 3.4 2.5 2.5 2.6 6.7 5.1 10.4 10.5 2.5 3.0 7.8 5.3 3.9 8.0 5.0 11.0 7.4 14.0 7.5 3.0 5.5 10.0 6.1 4.0 3.9 37.8 10.7 6.7 23.4 5.4 3.9 5.5 8.2 4.2 8.1 3.5 5.4 3.9 2.4 6.3 9.6 7.5 2.9 9.0 6.0 24.3 4.0 17.8 8.3 8.6 9.3 8.3 2.8 4.8 11.5 5.0 19.0 5.3 4.2 4.5 12.3 4.2 2.9 8.0 7.2 5.3 3.9 12.4 5.8 8.5 5.2 21.2 5.6 0.0 0.7 0.1 2.6 0.3 2.2 0.9 3.3 2.4 0.9 1.0 3.9 3.1 0.1 2.4 0.2 1.2 2.7 1.8 3.0 2.5 6.1 5.0 4.7 2.5 3.8 2.3 3.7 1.3 3.4 2.6 3.8 16.0 5.8 0.0 1.5 0.0 0.0 0.0 0.0 0.0 7.3 8.9 0.7 0.0 5.6 16.5 0.0 0.0 3.4 0.7 5.9 9.0 0.0 3.8 3.6 2.3 0.0 0.0 0.3 8.8 0.0 2.2 0.0 2.6 2.5 5.3 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 4.6 0.0 0.0 0.0 0.1 7.7 0.0 0.0 0.7 0.0 1.1 40.7 2.9 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 2.3 5.4 0.0 0.0 SUSD4 FLJ10052 ENSG00000143502 "Sushi domain containing 4" Q5VX71 1 223220819-223364233 "Predicted intracellular proteins, Predicted membrane proteins" "Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.0;esophagus: 51.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 83.7;Inhibitory neurons: 89.7;Oligodendrocyte precursor cells: 101.6;Squamous epithelial cells: 68.3;Theca cells: 65.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 6.8;naive CD4 T-cell: 10.2" "Lineage enriched" "Detected in single" 40 "T-cells: 10.2" "Cell line enhanced" "Detected in some" "HaCaT: 9.7;RPTEC TERT1: 11.1;SCLC-21H: 36.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058296 Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA058296: AB_2683672" "unprognostic (2.90e-1)" "unprognostic (2.90e-3)" "unprognostic (1.27e-3)" "prognostic unfavorable (4.28e-4)" "unprognostic (2.12e-1)" "unprognostic (7.01e-2)" "unprognostic (7.53e-3)" "unprognostic (1.82e-3)" "unprognostic (7.94e-2)" "unprognostic (1.57e-1)" "unprognostic (1.27e-3)" "unprognostic (1.36e-1)" "unprognostic (6.51e-6)" "unprognostic (3.64e-2)" "unprognostic (5.11e-2)" "unprognostic (3.03e-1)" "unprognostic (7.11e-2)" 0.4 6.0 28.4 0.8 21.7 0.4 8.7 5.4 63.7 9.5 0.0 1.3 1.0 0.3 25.1 51.1 3.5 0.7 23.0 69.0 26.8 19.5 3.8 2.8 1.6 9.4 10.4 45.3 10.7 14.9 26.0 0.5 15.9 6.0 0.2 12.2 17.0 4.3 3.5 7.8 0.6 0.4 5.0 0.4 11.0 6.6 21.4 3.4 1.0 2.2 15.0 3.6 25.3 16.2 5.9 0.5 0.2 0.0 0.0 0.0 0.1 0.8 0.4 1.0 0.5 5.8 1.8 0.0 1.8 0.2 0.0 9.7 0.2 1.5 0.9 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.6 0.2 0.0 6.6 0.5 0.0 0.5 3.9 3.8 0.0 0.2 3.0 1.3 0.0 0.2 0.1 11.1 2.8 36.3 0.4 0.0 3.2 0.0 0.8 2.1 0.2 0.0 1.7 6.2 0.0 2.9 0.7 0.1 0.0 0.1 0.1 0.8 0.0 0.1 0.0 0.3 0.1 5.5 0.0 6.8 1.7 0.0 0.0 10.2 1.9 0.0 0.2 0.0 0.0 0.9 1.4 28.4 21.7 5.4 63.7 69.0 26.8 9.4 10.4 15.9 5.0 21.4 16.2 0.2 0.0 4.8 6.2 0.0 0.6 8.6 8.4 10.2 17.9 9.7 5.0 9.5 5.7 14.8 16.5 10.4 0.1 0.3 0.1 31.3 0.6 3.1 4.0 0.4 0.6 1.2 0.0 83.7 6.9 0.0 3.8 2.6 6.1 0.0 9.1 0.4 1.8 2.8 21.9 89.7 0.1 2.0 0.6 0.3 3.4 20.5 0.3 5.4 8.4 0.0 1.6 0.0 101.6 2.5 2.6 0.0 12.4 0.1 4.6 0.0 0.3 5.4 6.2 0.0 1.4 2.8 1.3 10.7 68.3 1.7 0.0 1.7 65.5 0.3 25.7 SYT7 "IPCA-7, MGC150517, PCANAP7, SYT-VII" ENSG00000011347 "Synaptotagmin 7" O43581 11 61513714-61581148 "Predicted intracellular proteins, Predicted membrane proteins" Exocytosis Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 78.4;liver: 86.7;salivary gland: 57.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 45.2;Enteroendocrine cells: 49.8;Excitatory neurons: 82.1;Hepatocytes: 70.7;Prostatic glandular cells: 36.8;Syncytiotrophoblasts: 66.4" "Cancer enhanced" "Detected in all" "prostate cancer: 54.4" "Region enhanced" "Detected in many" "cerebral cortex: 78.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 35.0;hTERT-HME1: 89.5;RT4: 37.8;SCLC-21H: 28.4;SK-BR-3: 40.7;T-47d: 39.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012869 Enhanced NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA012869: AB_1857698" "unprognostic (7.09e-2)" "unprognostic (8.26e-2)" "unprognostic (2.43e-1)" "unprognostic (2.10e-2)" "unprognostic (5.42e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (4.37e-2)" "unprognostic (5.08e-2)" "unprognostic (2.74e-3)" "unprognostic (1.79e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (2.08e-1)" "unprognostic (1.69e-1)" "unprognostic (2.23e-3)" "unprognostic (2.47e-1)" 3.8 4.3 17.7 1.2 33.8 0.1 9.2 0.0 78.4 3.1 0.0 5.0 2.3 2.6 1.8 3.5 3.4 1.2 19.0 30.7 1.9 24.7 86.7 1.9 0.3 0.0 1.9 1.3 16.7 5.7 51.6 18.4 0.0 50.8 5.3 8.0 57.0 0.9 3.6 4.2 5.2 1.8 0.0 2.1 3.7 4.0 13.9 0.4 8.0 1.8 0.3 1.9 3.3 38.5 13.4 1.9 0.5 0.2 1.0 14.1 10.4 0.2 35.0 0.6 0.5 3.5 6.9 0.0 0.6 0.2 1.3 6.9 0.9 0.2 0.2 0.2 1.7 0.0 1.7 2.1 0.9 0.1 0.1 0.4 7.8 4.2 89.5 0.2 0.2 0.8 0.1 0.2 0.5 21.6 0.1 0.3 2.4 24.8 14.1 0.0 0.7 1.7 0.0 37.8 28.4 5.2 1.9 40.7 0.3 5.6 39.8 0.0 0.0 8.6 3.1 10.1 0.2 0.0 0.0 0.1 0.9 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 33.8 0.0 78.4 30.7 1.9 0.0 1.9 0.0 0.0 13.9 38.5 10.6 0.0 0.5 4.2 0.2 0.3 0.4 5.1 0.0 22.6 23.2 16.3 22.3 1.5 5.0 5.5 0.0 45.2 0.6 1.9 5.9 1.2 8.4 0.3 4.3 4.9 49.8 2.7 82.1 1.6 3.4 3.0 0.0 0.5 0.0 5.9 4.6 70.7 4.0 21.9 17.8 30.2 6.1 1.0 0.0 7.6 3.4 0.1 1.8 7.5 0.0 0.6 0.0 6.0 2.5 1.0 4.6 2.2 0.0 36.8 3.5 0.1 1.3 3.5 0.0 2.8 1.4 0.8 3.9 0.9 0.1 66.4 0.2 0.6 2.4 1.7 TFAP2B AP2-B ENSG00000008196 "Transcription factor AP-2 beta" Q92481 6 50818723-50847619 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 33.3;retina: 14.8" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 145.7;Bipolar cells: 76.4;Horizontal cells: 437.4;Melanocytes: 106.7" "Cancer enriched" "Detected in some" 8 "breast cancer: 12.1" "Group enriched" "Detected in many" 6 "cerebellum: 3.5;medulla oblongata: 3.9;midbrain: 9.0;pons: 10.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 109.6;SH-SY5Y: 208.1" "Region enhanced" "Detected in many" "cerebellum: 10.0" "Low region specificity" "Detected in many" "HPA034683, HPA062942" Enhanced Approved Nucleoplasm NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA034683: AB_10670966, HPA062942: AB_2684909" "unprognostic (2.02e-1)" "unprognostic (2.29e-2)" "unprognostic (4.27e-2)" "unprognostic (5.88e-4)" "unprognostic (9.76e-2)" "unprognostic (2.10e-1)" "unprognostic (1.00e-1)" "unprognostic (4.57e-1)" "unprognostic (6.58e-6)" "unprognostic (1.13e-2)" "unprognostic (1.88e-1)" "unprognostic (7.17e-3)" 0.1 3.4 0.0 0.0 0.0 0.0 8.2 3.5 0.1 0.1 0.0 0.1 0.0 0.0 33.3 3.9 0.0 0.0 0.0 0.0 0.1 9.8 0.0 0.0 0.0 3.9 9.0 0.0 0.0 0.0 0.6 0.2 10.2 0.0 0.0 14.8 6.4 0.7 0.0 8.6 0.0 0.0 0.6 0.0 0.0 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 109.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 35.5 0.1 0.2 208.1 0.0 0.8 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.1 3.9 9.0 10.2 0.6 1.1 0.2 0.2 0.0 0.0 0.0 0.0 11.7 0.0 0.0 145.7 76.4 43.0 29.7 0.9 0.0 0.0 51.5 8.4 14.9 0.1 0.0 54.8 0.0 17.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 4.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 437.4 0.0 0.0 0.0 0.0 1.5 2.0 0.0 0.5 106.7 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.4 1.2 0.0 0.0 0.7 0.0 11.8 0.0 0.0 0.3 1.9 0.6 31.1 4.3 4.9 0.2 0.0 0.0 0.0 TUBB2B "bA506K6.1, DKFZp566F223, MGC8685" ENSG00000137285 "Tubulin beta 2B class IIb" Q9BVA1 6 3223324-3231730 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 387.9;choroid plexus: 154.0" "Group enriched" "Detected in many" 4 "Distal tubular cells: 414.8;Horizontal cells: 430.7;Muller glia cells: 847.3;Skeletal myocytes: 350.1" "Cancer enriched" "Detected in many" 9 "glioma: 216.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 541.9;CACO-2: 415.3;NTERA-2: 268.0;RPMI-8226: 277.7;SCLC-21H: 797.7;SH-SY5Y: 390.2;SuSa: 245.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043640, HPA046280" Supported Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 43: B-cells - Humoral immune response" "Cluster 70: Brain - Nervous system development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 5: Muller glia cells - Visual perception" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (2.66e-2)" "unprognostic (3.41e-1)" "unprognostic (5.92e-3)" "prognostic unfavorable (1.94e-4)" "unprognostic (6.81e-2)" "unprognostic (3.26e-2)" "unprognostic (9.03e-3)" "unprognostic (8.33e-2)" "unprognostic (1.08e-1)" "unprognostic (2.02e-1)" "unprognostic (3.78e-3)" "unprognostic (3.34e-2)" "unprognostic (2.03e-2)" "unprognostic (6.24e-3)" "unprognostic (6.04e-2)" "unprognostic (3.58e-4)" "unprognostic (2.30e-3)" 4.0 7.2 298.1 8.1 324.5 1.0 5.0 348.4 387.9 9.9 154.0 17.0 2.4 4.2 45.5 2.4 3.3 3.8 4.6 258.8 356.9 11.6 1.0 1.4 8.1 363.3 349.9 1.1 5.7 0.0 35.1 4.4 354.5 3.7 2.6 65.3 10.8 4.6 6.2 3.9 6.1 7.3 337.2 0.7 4.5 1.0 369.1 2.3 0.9 1.6 5.7 2.6 5.6 383.9 0.0 8.2 541.9 164.2 0.6 0.2 0.9 5.1 7.4 20.8 45.0 415.3 2.0 0.9 5.6 5.7 0.0 1.3 212.8 0.7 12.0 1.6 98.3 0.2 0.0 33.2 1.1 0.1 6.1 3.1 0.0 2.3 0.0 7.6 1.4 0.5 6.8 1.2 7.6 0.3 1.5 0.4 268.0 1.0 17.6 0.6 26.3 277.7 2.9 0.8 797.7 390.2 0.3 1.7 4.3 245.9 3.2 0.0 0.0 1.9 89.9 6.3 2.2 51.6 0.1 0.0 0.8 0.1 30.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 298.1 324.5 348.4 387.9 258.8 356.9 363.3 349.9 354.5 337.2 369.1 383.9 3.6 0.0 0.0 109.4 1.9 8.7 2.3 1.8 4.6 63.5 3.9 31.9 40.1 5.7 0.3 7.3 16.7 0.7 1.0 0.9 414.8 15.4 5.8 2.7 3.3 7.6 66.7 0.0 2.4 3.5 1.2 18.7 7.1 3.9 0.0 0.5 0.7 0.6 3.0 430.7 19.4 1.0 24.4 0.0 12.4 7.1 0.3 1.0 92.5 9.4 3.6 847.3 0.0 37.2 21.6 12.0 0.1 0.0 8.4 3.9 0.2 2.0 0.0 43.1 0.0 350.1 19.1 1.3 6.2 3.1 2.7 0.8 0.6 0.0 0.6 1.1 WNK4 PRKWNK4 ENSG00000126562 "WNK lysine deficient protein kinase 4" Q96J92 17 42780610-42797066 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 11.0;kidney: 37.6;prostate: 11.6" "Cell type enriched" "Detected in some" 4 "Distal tubular cells: 160.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 32.6;K-562: 36.8;TIME: 34.1;WM-115: 23.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016500 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "HPA016500: AB_10962984" "unprognostic (6.34e-3)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" "unprognostic (5.58e-2)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (2.48e-1)" "unprognostic (1.69e-1)" "unprognostic (5.84e-2)" "unprognostic (3.94e-1)" "unprognostic (2.08e-3)" "unprognostic (4.33e-3)" "unprognostic (7.70e-3)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (1.43e-1)" "unprognostic (7.99e-2)" 1.3 0.0 0.7 1.1 0.9 0.0 2.8 0.8 3.3 0.6 0.3 9.8 1.9 0.2 0.7 8.9 0.4 0.0 0.1 1.7 1.1 37.6 0.2 0.1 0.1 1.1 0.7 4.3 0.2 0.0 1.2 0.0 0.7 11.6 11.0 0.6 1.8 1.1 0.0 0.5 3.7 0.4 0.6 0.1 3.4 0.2 1.0 0.0 0.0 0.3 0.1 0.2 0.4 1.0 2.1 1.2 0.6 0.0 0.7 0.2 4.8 11.9 4.8 4.5 1.3 0.7 1.0 0.6 6.8 32.6 1.2 0.0 0.2 0.3 8.6 0.6 1.8 0.1 0.0 4.7 7.4 0.3 0.7 3.9 1.4 6.4 2.1 2.1 0.3 0.4 36.8 1.3 0.0 1.0 0.0 1.1 0.3 2.0 8.2 0.6 1.2 0.0 0.0 0.5 0.0 0.2 0.1 0.2 1.7 4.1 2.4 2.7 34.1 0.3 3.1 0.5 0.4 6.2 5.3 1.2 0.0 2.1 23.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.8 3.3 1.7 1.1 1.1 0.7 0.7 0.6 1.0 1.0 0.2 0.0 0.6 0.0 0.5 0.0 0.2 0.0 0.6 0.2 7.1 4.1 1.0 1.5 0.6 7.3 0.0 0.0 0.3 8.0 160.4 0.0 0.0 5.1 1.1 0.2 13.1 0.0 0.2 0.2 0.2 0.1 3.1 6.7 4.5 0.1 0.7 0.0 0.0 0.0 0.2 40.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 3.2 0.4 0.0 3.6 0.9 1.0 2.9 0.5 0.0 0.2 0.5 0.8 0.8 12.1 0.4 0.0 0.2 0.0 13.1 0.3