Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" A1CF "ACF, ACF64, ACF65, APOBEC1CF, ASP" ENSG00000148584 "APOBEC1 complementation factor" Q9NQ94 10 50799409-50885675 "Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 144.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 150.2;Distal enterocytes: 71.3;Enteroendocrine cells: 116.5;Hepatocytes: 337.9;Paneth cells: 83.8;Proximal enterocytes: 147.5;Proximal tubular cells: 118.4" "Cancer enriched" "Detected in some" 6 "liver cancer: 18.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 24 "CACO-2: 23.5;Hep G2: 60.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA037779, HPA044079" Enhanced Supported Nucleoplasm NA NA "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "HPA037779: AB_10670529, HPA044079: AB_2678800" "unprognostic (3.87e-3)" "unprognostic (7.86e-2)" "unprognostic (2.34e-1)" "unprognostic (2.21e-3)" "unprognostic (2.73e-1)" "unprognostic (4.61e-3)" "unprognostic (1.71e-1)" "unprognostic (7.38e-3)" "unprognostic (1.30e-2)" "unprognostic (2.46e-2)" "unprognostic (1.20e-1)" "unprognostic (1.90e-3)" "unprognostic (1.97e-2)" "unprognostic (2.77e-1)" "unprognostic (2.19e-2)" "unprognostic (8.50e-4)" 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 11.1 23.4 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 12.5 144.0 0.0 0.0 0.0 0.0 0.1 7.5 0.0 0.0 0.0 0.0 0.0 10.3 0.1 0.0 0.0 0.0 0.0 26.8 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 60.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.6 150.2 0.0 3.7 2.1 0.0 0.0 71.3 9.8 1.2 0.0 0.0 0.0 0.6 116.5 5.3 0.4 11.4 0.0 0.0 0.0 0.0 0.0 0.0 6.1 337.9 0.0 0.0 0.3 52.0 0.0 8.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 10.1 83.8 0.0 0.0 0.1 147.5 118.4 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 35.1 0.1 ABAT "GABA-T, GABAT" ENSG00000183044 "4-aminobutyrate aminotransferase" P80404 16 8674596-8784575 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Neurotransmitter degradation" "Aminotransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 137.9;kidney: 133.3;liver: 345.6;pancreas: 138.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 268.2;Inhibitory neurons: 95.0;Oligodendrocyte precursor cells: 76.9;Proximal tubular cells: 94.9" "Cancer enhanced" "Detected in all" "glioma: 27.3;liver cancer: 26.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 127.5;MCF7: 81.9;RH-30: 67.4;T-47d: 42.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041528, HPA041690" Enhanced Supported Supported Mitochondria No No 2100000 "Cluster 14: Monocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA041528: AB_10795690, HPA041690: AB_10794674" "unprognostic (1.77e-2)" "unprognostic (3.27e-1)" "unprognostic (1.00e-1)" "unprognostic (2.71e-1)" "unprognostic (2.90e-1)" "unprognostic (2.05e-1)" "prognostic favorable (5.36e-5)" "prognostic favorable (5.93e-4)" "unprognostic (1.71e-1)" "unprognostic (1.30e-1)" "unprognostic (1.56e-2)" "unprognostic (1.04e-1)" "prognostic favorable (5.44e-8)" "unprognostic (2.10e-1)" "unprognostic (2.48e-2)" "unprognostic (3.80e-1)" "unprognostic (1.50e-2)" 3.3 27.7 94.6 4.7 105.4 2.2 5.1 85.2 103.4 3.8 70.7 7.6 43.6 3.8 9.6 7.7 6.2 4.4 14.1 90.2 120.7 133.3 345.6 4.5 5.0 90.8 107.4 10.5 138.3 8.2 55.8 3.4 137.6 21.7 7.8 29.6 6.5 3.5 1.6 2.7 20.1 2.7 88.1 4.1 7.4 13.4 137.9 4.2 29.3 1.4 5.9 9.9 4.1 70.9 0.7 0.2 32.1 18.7 5.0 1.7 2.0 4.2 2.2 1.8 0.7 12.7 0.9 4.0 1.4 2.3 1.2 8.3 2.1 7.7 2.4 2.3 2.1 5.5 0.1 127.5 8.1 1.3 8.3 6.5 3.4 3.2 1.4 0.9 0.6 10.7 1.1 2.6 0.6 81.9 2.1 0.6 2.8 23.2 0.3 9.7 67.4 1.8 1.2 20.9 5.1 15.7 1.9 1.0 0.2 6.2 42.6 3.4 0.6 0.8 5.7 2.7 0.1 3.0 0.3 0.8 0.8 5.7 4.2 0.7 1.9 2.7 1.5 2.2 0.7 0.6 1.0 1.1 1.2 1.2 0.7 1.1 6.1 1.2 4.2 0.2 1.1 1.2 94.6 105.4 85.2 103.4 90.2 120.7 90.8 107.4 137.6 88.1 137.9 70.9 1.7 0.0 6.9 39.5 6.1 1.5 4.0 3.3 2.2 27.3 9.1 5.0 10.8 20.0 5.8 1.8 4.2 1.4 5.3 8.9 23.5 1.6 13.0 12.9 6.2 2.4 15.6 13.9 41.8 6.2 1.5 3.2 5.6 12.9 1.3 59.5 7.1 268.2 5.2 35.3 95.0 3.9 2.0 15.7 7.4 8.7 3.7 8.2 1.8 19.7 6.5 48.6 9.2 76.9 17.7 6.8 6.1 4.5 1.0 7.4 15.7 94.9 3.6 5.8 0.0 4.3 3.8 3.7 0.9 9.5 0.6 1.4 6.3 2.3 6.9 5.0 ABCC2 "CMOAT, cMRP, DJS, MRP2" ENSG00000023839 "ATP binding cassette subfamily C member 2" Q92887 10 99782640-99852594 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport Translocase "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 40.2;liver: 121.7" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 70.7" "Cancer enriched" "Detected in many" 5 "liver cancer: 24.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "A549: 204.4;Hep G2: 208.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA071145 Enhanced NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA071145: " "unprognostic (1.49e-3)" "unprognostic (5.92e-2)" "unprognostic (1.59e-1)" "unprognostic (3.67e-1)" "unprognostic (1.93e-2)" "unprognostic (2.33e-1)" "unprognostic (2.51e-1)" "unprognostic (7.15e-3)" "unprognostic (5.68e-2)" "unprognostic (2.01e-1)" "unprognostic (4.30e-1)" "unprognostic (1.40e-3)" "prognostic unfavorable (1.93e-5)" "unprognostic (1.31e-1)" "unprognostic (3.22e-2)" "unprognostic (2.95e-1)" "unprognostic (1.26e-2)" 1.6 0.4 0.2 0.7 0.4 0.8 3.0 0.5 0.3 0.5 0.1 0.6 39.1 0.4 0.2 0.3 0.7 24.4 0.2 0.3 0.2 18.5 121.7 0.5 0.7 0.4 0.3 0.3 1.1 0.1 0.1 0.5 0.4 0.4 0.4 3.9 0.5 0.2 1.1 1.7 40.2 0.2 0.2 1.4 0.7 0.7 0.3 0.8 0.4 0.7 0.5 1.3 0.5 0.6 0.3 204.4 3.5 10.2 15.3 12.0 3.4 0.5 1.3 0.5 0.6 44.6 0.3 0.4 0.3 0.7 0.5 1.3 0.3 0.4 0.6 0.5 0.3 0.0 1.0 208.7 0.5 0.3 0.7 1.9 13.9 1.5 1.4 0.2 0.4 0.6 0.0 0.3 0.2 1.0 0.2 1.4 0.3 39.8 0.3 0.3 0.2 0.4 1.4 0.3 0.1 0.2 0.5 3.4 25.9 0.4 0.1 0.4 0.7 0.6 0.6 0.9 0.6 0.8 0.1 0.2 16.1 1.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.5 0.3 0.3 0.2 0.4 0.3 0.4 0.2 0.3 0.6 0.7 0.0 0.0 2.3 0.4 0.0 0.2 0.2 0.0 0.3 0.1 0.0 0.5 1.5 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.2 2.6 2.9 0.2 0.3 0.0 0.4 1.0 0.4 0.0 1.7 0.0 0.6 1.3 0.1 1.4 70.7 0.2 0.0 1.3 0.6 0.0 1.0 0.0 1.1 0.3 0.4 5.4 1.9 0.3 0.1 0.0 1.0 2.2 0.1 0.0 0.0 0.1 0.2 15.5 10.7 2.8 1.5 0.0 0.4 0.5 1.2 0.7 0.1 0.0 1.6 0.4 0.1 0.4 0.0 ABCC6 "ARA, EST349056, MLP1, MRP6, PXE, URG7" ENSG00000091262 "ATP binding cassette subfamily C member 6" O95255 16 16149565-16223522 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Transport, Vision" Translocase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 134.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 31.5;Distal tubular cells: 45.0;Hepatocytes: 77.9;Proximal enterocytes: 33.7;Proximal tubular cells: 151.1" "Group enriched" "Detected in many" 5 "liver cancer: 16.7;renal cancer: 5.0" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 6 "classical monocyte: 3.4" "Lineage enriched" "Detected in single" 7 "monocytes: 3.4" "Cell line enriched" "Detected in some" 8 "Hep G2: 68.4" "Not detected" "Not detected" HPA038105 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" Nucleoplasm "HPA038105: AB_2675835" "unprognostic (1.32e-1)" "unprognostic (1.11e-1)" "unprognostic (5.98e-2)" "unprognostic (3.15e-2)" "unprognostic (1.59e-1)" "unprognostic (3.09e-1)" "prognostic favorable (3.82e-4)" "unprognostic (6.54e-3)" "unprognostic (3.64e-1)" "unprognostic (9.10e-2)" "unprognostic (1.30e-1)" "unprognostic (1.65e-1)" "unprognostic (1.12e-3)" "unprognostic (3.42e-1)" "unprognostic (2.00e-1)" "unprognostic (4.91e-2)" "unprognostic (1.41e-1)" 5.6 3.6 0.7 0.3 0.7 0.7 3.8 0.7 1.1 1.0 0.8 5.7 13.2 0.3 0.6 0.3 1.5 2.9 2.6 0.7 0.7 27.4 134.2 7.4 0.0 0.8 0.9 1.0 17.2 2.1 0.9 0.2 0.8 2.9 2.8 0.3 12.7 1.0 4.6 0.4 7.9 0.3 0.7 0.7 6.4 0.4 0.8 0.0 5.6 0.1 0.0 0.4 0.7 0.7 0.0 1.5 0.7 0.0 0.0 0.8 1.8 0.0 0.4 1.0 1.6 7.1 2.3 0.0 0.8 0.0 0.2 0.0 0.7 0.1 0.6 0.0 0.7 1.8 0.2 68.4 0.4 0.0 0.0 2.7 0.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.2 0.6 0.0 0.0 0.0 0.0 2.3 0.0 0.1 1.0 0.0 0.8 0.1 0.3 8.4 5.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 3.4 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.7 0.7 0.7 1.1 0.7 0.7 0.8 0.9 0.8 0.7 0.8 0.7 0.3 28.9 31.5 2.9 1.9 0.1 0.5 3.2 0.0 1.0 4.3 3.6 3.3 18.6 8.7 9.2 0.0 0.0 0.0 13.7 45.0 2.2 0.5 4.8 1.0 0.8 3.0 2.7 1.0 7.9 0.0 1.7 13.3 1.0 1.3 1.9 1.8 77.9 1.0 0.0 1.1 10.9 0.0 3.5 0.0 0.7 1.5 1.8 1.8 3.7 3.1 1.5 0.0 1.0 0.4 2.2 8.1 5.7 0.3 2.0 33.7 151.1 25.4 0.6 0.0 0.3 1.2 0.4 0.3 0.2 0.9 0.0 1.4 1.8 11.9 0.7 AC005726.1 ENSG00000258472 "Novel protein" 17 28455752-28614185 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 13.2;Club cells: 5.6;granulocytes: 6.3;Proximal tubular cells: 20.4;Respiratory ciliated cells: 5.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.0" HPA046590 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" Nucleoplasm "HPA046590: AB_2679710" "unprognostic (1.26e-2)" "unprognostic (1.82e-1)" "unprognostic (6.04e-3)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" "unprognostic (2.23e-3)" "unprognostic (2.76e-3)" "unprognostic (7.25e-2)" "unprognostic (5.96e-2)" "unprognostic (4.58e-2)" "unprognostic (9.22e-3)" "unprognostic (3.17e-3)" "unprognostic (1.49e-4)" "unprognostic (1.25e-1)" "unprognostic (2.65e-1)" "unprognostic (7.50e-2)" "unprognostic (3.79e-4)" 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 9.6 13.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.3 2.4 0.0 0.0 5.6 3.7 0.0 1.7 0.5 0.0 1.9 1.2 0.0 1.7 2.4 1.4 0.0 0.0 0.0 2.0 0.8 1.6 0.0 3.2 6.3 2.6 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 20.4 5.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 5.3 1.1 1.2 0.0 0.0 ACAA1 ENSG00000060971 "Acetyl-CoA acyltransferase 1" P09110 3 38103129-38137242 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "kidney: 212.6;liver: 659.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 356.8;Hepatocytes: 686.0;Proximal enterocytes: 441.1;Proximal tubular cells: 721.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 224.0;SK-BR-3: 342.9" "Low region specificity" "Detected in all" "HPA006764, HPA007244" Enhanced Supported Peroxisomes NA NA 4700000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Peroxisomes "HPA006764: AB_1078085, HPA007244: AB_1078084" "prognostic favorable (3.00e-4)" "unprognostic (5.57e-2)" "unprognostic (4.54e-2)" "prognostic favorable (7.53e-4)" "unprognostic (2.63e-1)" "prognostic favorable (1.23e-4)" "unprognostic (9.35e-3)" "unprognostic (2.91e-2)" "unprognostic (8.11e-2)" "unprognostic (2.22e-1)" "unprognostic (2.24e-1)" "unprognostic (4.90e-1)" "prognostic favorable (6.99e-9)" "unprognostic (1.72e-1)" "unprognostic (1.99e-1)" "unprognostic (2.50e-2)" "unprognostic (1.65e-2)" 42.8 54.1 47.5 24.0 54.4 44.7 41.2 54.3 49.5 28.3 42.3 56.9 101.0 20.8 44.6 56.7 19.4 29.8 84.8 44.6 48.7 212.6 659.3 34.9 26.1 54.2 50.4 20.9 59.3 47.9 24.8 17.2 53.0 55.1 51.2 4.9 38.9 25.3 48.2 30.7 89.5 18.7 50.9 41.3 42.1 15.5 53.6 28.0 32.1 53.8 30.0 43.7 33.5 54.9 35.5 39.8 13.0 40.7 55.6 32.2 44.6 32.2 47.0 36.3 34.5 52.8 38.8 21.1 22.6 52.0 17.4 24.5 34.9 54.0 20.0 31.0 37.2 27.0 35.4 155.5 35.3 63.3 59.8 59.0 39.3 31.2 22.5 23.9 49.9 49.7 26.2 24.2 41.3 49.2 60.3 45.3 13.3 224.0 47.0 13.9 25.0 34.3 103.4 110.4 10.9 16.5 31.7 342.9 23.7 18.0 35.1 48.9 36.8 21.9 21.1 43.2 44.2 31.9 21.7 16.1 34.8 54.4 34.7 79.9 114.4 130.4 48.8 159.1 41.2 33.9 45.7 47.4 178.1 36.0 45.2 42.5 76.3 71.9 187.7 104.5 77.2 82.1 47.5 54.4 54.3 49.5 44.6 48.7 54.2 50.4 53.0 50.9 53.6 54.9 30.7 41.7 38.7 50.6 45.6 33.3 56.5 57.6 40.9 36.9 48.7 37.1 3.2 98.7 44.3 66.2 14.6 91.6 61.7 356.8 166.3 98.0 4.5 40.7 38.6 25.4 55.1 40.4 25.6 78.4 64.5 34.4 76.5 39.1 19.0 32.5 37.1 686.0 81.7 8.4 24.7 73.1 48.8 93.5 86.8 9.6 35.8 83.2 58.7 14.0 89.5 43.1 53.5 12.5 30.9 100.9 270.6 33.1 44.5 60.6 441.1 721.8 26.3 16.7 32.9 28.5 27.4 19.8 11.7 48.1 35.5 99.3 44.4 186.7 84.3 87.0 ACADSB "ACAD7, SBCAD" ENSG00000196177 "Acyl-CoA dehydrogenase short/branched chain" P45954 10 123008979-123058290 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 360.1" "Cell type enhanced" "Detected in all" "Hepatocytes: 499.5;Proximal tubular cells: 137.9" "Cancer enhanced" "Detected in all" "liver cancer: 32.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 54.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041458, HPA063555" Enhanced Supported Mitochondria NA NA 37000 "Cluster 2: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA041458: AB_2677491, HPA063555: " "unprognostic (1.53e-2)" "unprognostic (1.31e-1)" "unprognostic (3.91e-3)" "unprognostic (2.02e-1)" "unprognostic (1.25e-1)" "unprognostic (4.87e-2)" "unprognostic (4.15e-2)" "unprognostic (1.32e-3)" "unprognostic (1.30e-1)" "unprognostic (3.67e-1)" "prognostic favorable (3.40e-4)" "unprognostic (9.37e-3)" "prognostic favorable (6.37e-12)" "unprognostic (2.69e-1)" "unprognostic (7.20e-2)" "unprognostic (1.60e-3)" "unprognostic (7.14e-2)" 14.8 27.4 8.0 7.1 8.5 3.8 23.9 13.9 10.3 7.8 13.1 15.9 52.4 9.9 7.7 12.6 9.7 7.6 38.5 8.6 6.7 90.2 360.1 12.7 8.2 6.3 7.6 12.8 15.8 33.4 8.8 5.1 6.8 22.7 16.8 12.4 15.7 11.2 42.4 9.8 11.0 8.5 5.9 6.4 14.0 8.4 8.0 7.4 12.3 69.1 10.3 10.8 8.1 8.4 15.4 10.9 7.9 14.5 10.6 13.1 7.0 9.3 18.8 9.2 9.1 9.6 4.9 16.0 6.3 7.9 5.6 6.3 12.5 6.5 15.1 10.6 12.9 8.3 3.3 54.8 7.5 12.0 7.6 9.7 6.5 5.8 5.3 13.5 9.0 13.2 8.1 11.5 11.5 7.1 11.4 9.8 4.8 8.5 6.7 13.4 16.6 5.1 13.1 16.9 1.4 9.1 14.3 4.2 14.4 7.5 12.9 5.8 9.5 4.9 4.4 11.4 11.4 12.9 15.5 8.5 7.6 11.1 3.8 17.4 4.5 11.8 8.8 4.7 10.2 5.5 8.1 7.6 6.4 5.7 7.4 8.3 2.9 8.5 2.9 3.8 7.1 5.7 8.0 8.5 13.9 10.3 8.6 6.7 6.3 7.6 6.8 5.9 8.0 8.4 7.7 28.9 53.1 29.4 11.6 9.3 9.2 8.2 14.2 17.4 58.6 27.8 80.7 37.1 21.1 11.0 10.4 20.1 8.7 11.2 46.9 7.3 7.0 6.8 9.1 8.2 12.1 21.4 39.8 4.8 3.5 10.6 10.7 18.8 3.8 29.1 15.4 499.5 7.3 21.9 49.6 13.7 26.4 17.4 5.9 8.1 13.4 7.1 7.2 12.2 7.9 12.0 7.2 15.6 38.3 4.6 13.1 10.9 9.1 19.8 9.2 137.9 15.2 7.7 19.7 12.3 11.0 8.5 3.7 14.7 13.8 30.1 13.3 18.9 18.3 12.0 ACAT1 "ACAT, THIL" ENSG00000075239 "Acetyl-CoA acetyltransferase 1" P24752 11 108116695-108147603 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 622.7;liver: 969.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 508.4;Distal tubular cells: 698.5;Hepatocytes: 663.4;Proximal tubular cells: 1484.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 420.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004428, HPA007569" Enhanced Enhanced Mitochondria NA NA 1400000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA004428: AB_1078088, HPA007569: AB_1844482" "unprognostic (3.70e-3)" "unprognostic (2.23e-2)" "unprognostic (7.84e-3)" "unprognostic (4.65e-2)" "unprognostic (3.05e-2)" "unprognostic (1.12e-1)" "prognostic favorable (1.43e-5)" "unprognostic (3.59e-3)" "unprognostic (1.26e-1)" "unprognostic (5.20e-2)" "unprognostic (2.64e-2)" "unprognostic (1.13e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.96e-1)" "unprognostic (1.68e-1)" "unprognostic (8.06e-2)" "unprognostic (6.62e-3)" 135.4 151.3 45.2 24.3 45.3 38.4 56.9 47.1 60.1 41.0 91.8 96.3 103.9 44.0 34.1 45.0 39.1 25.6 289.4 42.7 46.8 622.7 969.5 43.7 28.2 44.8 45.2 64.7 110.6 95.9 30.9 24.7 45.2 45.6 85.6 26.2 104.1 60.2 461.1 45.3 53.2 57.1 46.7 29.3 81.9 66.3 45.6 19.1 65.5 410.8 29.7 44.1 34.6 47.7 76.9 57.7 48.2 139.3 155.9 138.7 25.1 71.7 78.8 77.7 91.7 168.1 77.3 41.3 116.8 83.6 119.7 78.1 142.3 70.3 83.3 84.9 114.6 117.4 64.6 163.9 107.6 112.9 64.9 124.6 77.1 69.2 127.4 91.5 85.0 92.3 172.1 61.8 128.6 45.8 57.4 122.4 48.2 103.1 135.0 88.1 96.9 420.4 114.7 50.4 75.7 88.1 111.6 152.7 83.0 37.0 132.2 97.6 87.4 83.2 44.5 73.5 88.8 18.9 57.8 77.7 37.6 233.1 59.6 1.4 17.1 4.7 25.3 25.5 29.9 29.2 28.8 30.0 33.5 13.8 25.5 22.4 1.8 13.4 27.8 11.3 35.7 23.4 45.2 45.3 47.1 60.1 42.7 46.8 44.8 45.2 45.2 46.7 45.6 47.7 50.5 54.5 91.8 17.9 37.2 43.1 52.2 48.9 23.9 30.1 34.6 29.6 508.4 78.6 33.5 104.8 27.1 39.9 29.2 125.0 698.5 43.1 345.7 62.2 42.1 62.5 30.0 74.7 35.1 60.5 41.5 57.1 29.0 25.7 27.8 48.6 99.2 663.4 97.9 38.7 37.8 38.5 97.6 73.6 27.8 65.3 66.5 39.1 58.7 30.0 50.1 39.1 25.7 22.6 26.5 33.8 93.8 82.4 52.7 27.8 51.4 1484.0 101.8 28.8 65.7 54.2 69.2 172.7 27.2 39.2 48.4 25.2 38.1 61.6 84.5 24.4 ACE "ACE1, CD143, DCP1" ENSG00000159640 "Angiotensin I converting enzyme" P12821 17 63477061-63498380 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 265.1;testis: 101.9" "Group enriched" "Detected in many" 20 "Early spermatids: 543.6;Late spermatids: 1322.9;Proximal enterocytes: 1172.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 8.1" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "ASC TERT1: 63.3;HUVEC TERT2: 33.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002426, CAB002921, HPA029298, HPA069790" Enhanced Approved Vesicles "Secreted to blood" NA NA 104000000 170000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB002426: AB_442052, CAB002921: , HPA029298: AB_10960255, HPA069790: AB_2686197" "unprognostic (4.72e-2)" "unprognostic (4.16e-1)" "unprognostic (1.93e-3)" "unprognostic (6.06e-2)" "unprognostic (2.78e-1)" "unprognostic (1.35e-2)" "unprognostic (4.37e-1)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-2)" "unprognostic (3.13e-2)" "unprognostic (2.38e-1)" "unprognostic (7.66e-2)" "unprognostic (9.07e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (2.76e-2)" 13.4 4.9 1.7 4.8 8.1 0.1 8.1 0.2 2.5 18.1 0.5 11.2 176.4 8.1 3.5 4.1 6.3 8.2 10.4 1.3 1.0 10.8 1.9 49.0 4.9 1.3 0.9 1.9 6.2 18.7 9.2 11.6 1.3 8.9 6.1 0.4 7.6 23.8 16.1 3.8 265.1 9.6 0.8 2.8 8.3 101.9 2.0 0.8 19.2 10.0 2.1 5.5 3.8 1.1 0.0 0.0 0.0 0.0 2.6 63.3 0.6 2.4 4.7 0.0 0.0 0.9 5.1 1.3 1.8 11.4 0.1 0.0 3.1 0.0 0.0 0.0 1.4 6.6 0.0 0.0 1.4 0.0 0.0 4.2 0.0 0.1 0.0 1.2 33.8 0.0 5.8 0.0 0.1 1.1 0.0 1.4 0.4 11.7 0.7 0.1 0.5 0.9 0.0 0.0 8.2 5.6 0.0 0.0 0.0 1.3 2.9 0.4 0.0 0.1 0.2 0.5 0.1 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.2 1.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.7 8.1 0.2 2.5 1.3 1.0 1.3 0.9 1.3 0.8 2.0 1.1 50.0 0.0 3.3 0.0 0.5 1.5 2.6 0.1 1.2 4.0 3.6 1.9 2.1 1.5 0.7 0.0 0.0 0.1 0.3 11.9 0.0 5.9 543.6 10.8 8.0 34.7 18.0 0.0 4.7 0.4 0.1 11.5 2.0 36.3 7.0 24.1 3.6 0.8 4.2 0.0 1.8 39.8 0.0 33.7 3.5 1322.9 4.4 13.6 3.6 4.7 0.0 1.8 0.0 1.0 0.2 0.7 40.9 2.6 0.1 4.2 1172.8 21.7 0.0 1.1 0.0 2.0 4.2 13.5 6.4 0.2 0.1 0.1 2.2 0.3 26.2 2.1 ACE2 ENSG00000130234 "Angiotensin I converting enzyme 2" Q9BYF1 X 15494566-15607236 "Enzymes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Host-virus interaction" "Carboxypeptidase, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 65.5;intestine: 242.2;kidney: 87.6" "Cell type enriched" "Detected in many" 5 "Proximal enterocytes: 294.8" "Group enriched" "Detected in many" 4 "colorectal cancer: 13.9;renal cancer: 26.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 1.2;NTERA-2: 1.2;SuSa: 1.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA000288, CAB026174, CAB026213, CAB080024, CAB080025, CAB080027, CAB080028" Enhanced "Secreted to blood" NA NA 400000 "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 45: Enterocytes - Digestion" "CAB026174: , CAB026213: , CAB080024: AB_10864415, CAB080025: AB_2809589, CAB080027: AB_2665870, CAB080028: AB_2665871, HPA000288: AB_1078160" "unprognostic (1.40e-1)" "unprognostic (7.26e-2)" "unprognostic (2.76e-2)" "unprognostic (5.71e-2)" "unprognostic (2.51e-1)" "unprognostic (5.26e-2)" "prognostic favorable (4.21e-4)" "unprognostic (2.34e-2)" "unprognostic (6.74e-3)" "unprognostic (2.54e-3)" "unprognostic (1.00e-1)" "unprognostic (1.74e-1)" "prognostic favorable (2.12e-5)" "unprognostic (1.94e-1)" "unprognostic (9.62e-2)" "unprognostic (2.11e-1)" "unprognostic (7.10e-2)" 8.9 0.5 0.1 1.4 0.1 0.6 4.3 0.4 0.3 0.6 1.9 9.9 183.3 0.5 0.5 1.8 1.5 65.5 42.7 0.2 0.2 87.6 5.7 0.8 0.4 0.2 0.2 1.8 2.5 1.5 0.1 1.2 0.2 0.4 5.9 0.3 1.4 4.1 0.7 0.3 242.2 0.5 0.1 0.1 2.6 49.7 0.2 0.5 4.5 0.5 0.2 0.8 1.2 0.2 0.0 0.0 0.3 0.0 0.2 0.0 0.8 0.1 0.0 0.2 0.2 0.2 0.3 0.4 0.3 0.0 0.3 0.7 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.5 1.2 1.2 0.0 0.0 0.3 0.2 0.5 0.2 0.4 0.2 0.9 0.0 0.4 0.0 1.9 0.4 0.4 0.1 0.0 0.0 0.3 0.4 0.1 0.5 0.5 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.3 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.4 0.0 0.5 1.3 1.4 0.1 0.5 5.0 0.0 0.0 1.6 0.0 11.2 55.8 2.6 0.0 0.0 4.2 0.1 22.9 3.9 1.2 0.5 1.1 0.3 1.0 7.2 0.0 0.8 0.8 0.3 4.6 0.0 0.6 0.0 3.9 0.0 0.9 0.8 0.0 0.8 8.2 0.0 0.0 0.0 1.4 8.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.9 5.1 6.0 0.0 1.0 294.8 48.8 2.0 0.0 19.7 0.0 8.9 1.1 1.0 0.0 0.1 12.7 0.3 0.1 10.6 2.2 ACMSD ENSG00000153086 "Aminocarboxymuconate semialdehyde decarboxylase" Q8TDX5 2 134838616-134902034 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "kidney: 141.1;liver: 162.5" "Group enriched" "Detected in some" 4 "Hepatocytes: 120.2;Proximal tubular cells: 408.1" "Group enriched" "Detected in some" 23 "liver cancer: 21.2;renal cancer: 19.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 21 "RPTEC TERT1: 26.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA010533, HPA011179" Enhanced Approved Cytosol NA NA 12000 "Cluster 37: B-cells - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA010533: AB_1844517, HPA011179: AB_1844516" "unprognostic (1.06e-2)" "unprognostic (5.30e-2)" "unprognostic (1.40e-1)" "unprognostic (7.50e-2)" "unprognostic (3.79e-2)" "unprognostic (1.36e-2)" "unprognostic (4.40e-3)" "unprognostic (1.15e-1)" "unprognostic (5.35e-4)" "unprognostic (7.60e-2)" "unprognostic (5.17e-2)" "unprognostic (2.44e-3)" "prognostic favorable (2.39e-4)" "unprognostic (1.26e-1)" "unprognostic (1.70e-1)" "unprognostic (2.93e-2)" "unprognostic (2.65e-5)" 0.0 0.2 0.1 0.1 0.0 0.2 0.1 0.9 0.3 0.0 0.0 0.1 0.9 0.1 0.0 0.0 0.0 7.1 0.2 0.0 0.3 141.1 162.5 0.1 0.3 0.8 0.2 0.7 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.4 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.6 0.4 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.4 0.1 1.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.7 0.4 0.1 0.8 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.4 0.6 0.0 0.0 0.3 0.8 0.3 1.2 0.2 0.5 0.1 0.6 0.3 26.7 0.4 1.0 0.3 0.1 0.3 0.4 0.8 0.2 0.7 1.0 0.0 0.4 0.2 0.8 0.2 0.1 0.5 0.2 0.3 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.9 0.3 0.0 0.3 0.8 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.2 50.1 0.0 9.2 0.0 0.0 0.0 0.0 54.8 0.2 0.0 0.0 0.1 0.0 0.0 2.7 8.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.9 120.2 0.0 0.0 7.3 0.0 0.0 1.9 0.0 0.0 0.0 2.8 0.0 1.0 0.0 0.0 0.0 2.5 1.9 0.1 0.0 0.0 0.0 0.0 0.0 408.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 ACOT12 "Cach, STARD15, THEAL" ENSG00000172497 "Acyl-CoA thioesterase 12" Q8WYK0 5 81329996-81394179 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "liver: 100.7" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 36.2" "Cancer enriched" "Detected in single" 76 "liver cancer: 13.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA037723 Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 62: Liver - Hemostasis" "Cluster 2: Hepatocytes - Metabolism" Cytosol "Nucleoplasm, Cytokinetic bridge" "HPA037723: AB_10672606" "unprognostic (6.06e-2)" "unprognostic (1.39e-1)" "prognostic favorable (5.30e-4)" "unprognostic (7.68e-2)" "unprognostic (8.22e-2)" "unprognostic (5.68e-3)" "unprognostic (2.46e-1)" "unprognostic (6.86e-2)" "unprognostic (1.46e-2)" "unprognostic (3.07e-1)" "unprognostic (1.06e-1)" 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.5 2.7 100.7 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.0 0.5 0.3 0.5 0.3 0.3 0.6 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.8 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 8.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 36.2 0.5 0.0 1.2 0.0 0.0 1.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 3.4 4.2 0.0 0.0 0.0 0.4 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 ACOT6 C14orf42 ENSG00000205669 "Acyl-CoA thioesterase 6" Q3I5F7 14 73610945-73619888 "Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.0;kidney: 3.7;liver: 3.1;skeletal muscle: 4.0" "Cell type enhanced" "Detected in some" "Astrocytes: 2.3;Excitatory neurons: 2.7;Hepatocytes: 3.4;Inhibitory neurons: 2.8;Proximal tubular cells: 5.7" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 5.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "T-47d: 10.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058258 Uncertain NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA058258: AB_2683656" "unprognostic (1.88e-1)" "unprognostic (1.77e-1)" "unprognostic (5.17e-2)" "unprognostic (1.24e-1)" "unprognostic (3.15e-2)" "unprognostic (6.52e-2)" "unprognostic (1.25e-1)" "unprognostic (5.07e-2)" "unprognostic (2.28e-1)" "unprognostic (5.04e-1)" 1.7 0.6 0.8 0.1 1.3 0.0 0.1 5.0 2.5 0.0 2.1 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.8 1.2 0.0 3.7 3.1 0.1 0.1 0.6 0.3 0.5 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.2 0.0 4.0 0.0 0.1 0.0 0.4 0.2 0.0 0.5 0.5 0.0 0.8 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.6 1.8 0.1 0.0 10.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.3 5.0 2.5 1.2 0.0 0.6 0.3 1.0 0.4 0.5 0.8 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.4 0.0 0.0 2.8 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACOT7 "ACH1, ACT, BACH, CTE-II, hBACH, LACH1, MGC1126" ENSG00000097021 "Acyl-CoA thioesterase 7" O00154 1 6264269-6393767 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 128.7" "Cell type enhanced" "Detected in many" "granulocytes: 137.2;Late spermatids: 160.8;Proximal enterocytes: 179.4;Proximal tubular cells: 253.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "NK-cell: 40.2;plasmacytoid DC: 35.7" "Group enriched" "Detected in many" 5 "dendritic cells: 35.7;NK-cells: 40.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025735, HPA025762" Enhanced Supported Nucleoplasm,Cytosol No No 26000 "Cluster 40: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA025735: AB_1844523, HPA025762: AB_1844524" "unprognostic (3.94e-2)" "unprognostic (1.74e-1)" "unprognostic (7.09e-2)" "unprognostic (4.33e-2)" "unprognostic (4.10e-2)" "unprognostic (5.06e-2)" "prognostic unfavorable (2.31e-5)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.35e-2)" "unprognostic (4.05e-2)" "unprognostic (1.15e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (2.55e-6)" "unprognostic (2.68e-2)" "unprognostic (1.45e-1)" "unprognostic (9.06e-2)" "unprognostic (3.72e-2)" 11.3 20.4 72.8 18.7 72.8 14.7 9.9 56.2 108.2 17.8 16.7 32.7 55.1 18.2 5.5 35.0 11.0 8.2 17.3 75.1 107.2 47.8 22.0 17.9 22.4 96.1 88.5 11.2 9.0 3.8 65.1 10.4 128.7 12.9 21.4 24.5 11.9 6.9 5.2 27.1 56.1 23.5 46.9 20.7 19.2 38.1 83.9 28.3 6.1 4.7 19.4 18.0 23.5 68.4 117.6 100.0 96.6 104.6 21.7 35.6 36.4 98.6 50.6 142.7 85.1 347.7 37.0 142.4 70.6 80.4 110.3 113.0 156.9 263.2 53.2 126.0 136.7 75.2 74.4 124.9 88.7 88.8 59.9 32.1 49.6 118.2 139.2 38.1 81.2 174.8 62.3 29.8 76.8 136.6 187.0 94.0 48.5 116.9 228.2 219.9 110.6 95.6 80.9 44.2 52.6 149.1 88.9 134.5 317.9 47.3 47.9 41.2 133.0 129.1 75.4 129.6 158.9 24.9 110.6 202.1 81.8 153.7 80.3 0.0 0.3 0.2 7.3 1.2 1.8 2.1 5.8 6.2 5.4 0.7 2.0 3.9 0.7 40.2 0.9 35.7 8.2 5.3 72.8 72.8 56.2 108.2 75.1 107.2 96.1 88.5 128.7 46.9 83.9 68.4 3.4 6.4 16.4 9.4 4.9 31.7 16.5 24.2 12.5 46.8 4.1 7.5 9.8 8.6 14.9 9.2 10.4 20.9 14.4 45.4 15.6 22.7 95.5 4.0 6.1 19.1 4.8 26.5 38.6 7.2 29.7 11.5 19.9 7.6 137.2 13.2 8.6 16.8 30.1 47.1 38.9 110.2 36.7 4.8 85.9 160.8 3.7 13.4 39.2 5.6 15.7 12.8 8.2 22.6 21.0 23.2 41.8 7.2 9.3 9.5 179.4 253.7 7.1 24.4 0.0 6.7 17.6 37.8 28.0 26.2 29.5 17.2 21.7 13.7 51.3 19.6 ACP5 "HPAP, TRAP" ENSG00000102575 "Acid phosphatase 5, tartrate resistant" P13686 19 11574660-11579008 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 174.1" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 426.9;Hofbauer cells: 426.7;Macrophages: 298.2;Proximal tubular cells: 145.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 200.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 41.1;K-562: 30.4;RPMI-8226: 41.4;SK-MEL-30: 127.6;U-138 MG: 102.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002584, HPA057655, HPA059463" Enhanced Uncertain Cytosol "Intracellular and membrane" NA NA 4000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB002584: AB_564039, HPA057655: AB_2683490, HPA059463: AB_2684028" "unprognostic (4.27e-2)" "unprognostic (2.05e-2)" "unprognostic (2.93e-1)" "unprognostic (8.60e-3)" "unprognostic (2.96e-1)" "unprognostic (1.95e-2)" "unprognostic (5.21e-2)" "unprognostic (5.17e-3)" "unprognostic (5.13e-2)" "unprognostic (3.80e-1)" "unprognostic (3.66e-3)" "unprognostic (9.09e-2)" "unprognostic (1.39e-2)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "unprognostic (1.05e-1)" "unprognostic (1.19e-1)" 9.4 6.0 2.2 42.4 3.9 9.4 25.6 2.5 21.4 34.7 3.0 46.4 31.9 19.2 7.8 23.4 8.6 26.7 5.1 1.9 3.9 74.0 32.5 174.1 87.1 4.1 3.1 20.3 11.9 2.4 1.3 13.3 6.0 19.6 36.4 20.1 14.3 7.0 1.4 24.9 30.2 13.3 4.1 43.5 38.7 4.0 15.7 25.4 3.0 5.0 43.6 33.1 11.3 5.7 10.2 1.1 0.0 0.2 0.5 0.0 41.1 1.1 25.8 0.0 0.1 0.4 0.3 1.4 1.8 9.0 5.9 0.3 0.0 4.5 0.1 12.1 0.8 0.3 0.0 5.0 1.4 0.1 0.6 0.0 4.1 0.4 0.0 0.0 0.0 0.0 30.4 0.2 0.0 2.3 0.9 1.4 0.8 0.3 0.7 0.4 1.8 41.4 0.0 0.4 0.7 1.0 0.0 0.0 127.6 1.1 0.2 0.4 0.9 102.9 1.2 1.8 0.3 0.7 5.7 0.6 23.7 0.1 4.0 0.4 35.3 76.6 15.8 36.1 8.8 200.1 26.0 19.6 7.3 110.9 35.3 20.2 10.4 13.3 36.3 62.5 67.8 36.4 2.2 3.9 2.5 21.4 1.9 3.9 4.1 3.1 6.0 4.1 15.7 5.7 2.2 9.6 7.8 0.0 75.7 10.3 11.0 21.8 25.0 18.3 14.6 18.4 1.4 15.7 5.7 7.3 18.8 33.4 21.2 7.0 9.8 1.8 0.2 0.7 9.1 30.9 3.0 24.5 0.0 11.3 32.7 19.8 10.7 0.9 63.7 0.8 426.9 8.4 426.7 1.7 0.0 4.7 10.2 106.0 68.6 0.7 1.8 298.2 14.2 1.0 79.8 48.5 8.2 0.0 0.1 4.4 20.4 12.0 33.4 14.5 12.7 145.8 2.5 41.4 0.0 0.4 2.8 0.1 0.2 14.6 11.1 26.1 29.5 0.1 6.7 6.1 ACSBG2 "BGR, DKFZp434K1635, PRTD-NY3" ENSG00000130377 "Acyl-CoA synthetase bubblegum family member 2" Q5FVE4 19 6135247-6193094 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Fatty acid metabolism, Lipid metabolism, Spermatogenesis" "Developmental protein, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 89 "testis: 129.3" "Group enriched" "Detected in some" 75 "Early spermatids: 533.6;Late spermatids: 1782.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043421, HPA051013" Enhanced Supported Cytosol NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA043421: AB_10794182, HPA051013: AB_2681311" "unprognostic (4.13e-2)" "unprognostic (1.28e-1)" "unprognostic (2.47e-1)" "unprognostic (3.27e-2)" "unprognostic (4.33e-2)" "unprognostic (1.92e-4)" "unprognostic (1.96e-2)" "unprognostic (4.17e-2)" "unprognostic (2.07e-1)" "unprognostic (2.62e-1)" "unprognostic (6.88e-3)" "unprognostic (3.13e-2)" "unprognostic (3.91e-3)" "unprognostic (2.20e-1)" "unprognostic (9.23e-2)" "unprognostic (8.78e-2)" "unprognostic (4.70e-4)" 0.1 0.0 0.2 0.0 0.2 0.0 0.2 1.4 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.7 0.3 0.0 0.0 0.0 0.5 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 129.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.4 0.2 0.3 0.1 0.7 0.3 0.2 0.1 0.2 0.9 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 533.6 0.0 0.1 0.6 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 1782.3 11.8 0.8 0.0 1.9 0.0 0.0 0.0 1.5 3.1 0.0 0.0 7.2 0.0 0.0 0.0 1.9 0.0 0.0 6.6 0.0 0.1 15.4 9.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 ACSF2 "ACSMW, FLJ20920" ENSG00000167107 "Acyl-CoA synthetase family member 2" Q96CM8 17 50426158-50474845 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 142.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 85.8;Proximal enterocytes: 78.2;Proximal tubular cells: 128.4;Syncytiotrophoblasts: 81.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 97.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024693 Enhanced Uncertain Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Microtubules, Cytosol" "HPA024693: AB_2671654" "unprognostic (1.40e-2)" "unprognostic (1.34e-1)" "unprognostic (2.58e-1)" "unprognostic (1.53e-1)" "unprognostic (1.06e-1)" "unprognostic (2.11e-1)" "unprognostic (8.48e-2)" "unprognostic (1.14e-2)" "unprognostic (6.49e-2)" "unprognostic (7.83e-2)" "unprognostic (2.41e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.72e-2)" "unprognostic (1.11e-1)" "unprognostic (2.45e-2)" "prognostic favorable (2.41e-4)" 24.8 71.9 7.6 5.7 8.5 3.3 21.0 7.7 10.1 18.9 8.6 26.9 22.1 6.7 15.8 7.7 9.7 10.8 25.9 7.1 7.0 142.1 36.4 17.8 8.5 8.5 7.3 19.3 6.8 9.9 2.9 15.4 8.0 15.0 17.5 1.1 15.8 16.0 41.3 22.5 20.2 5.4 8.2 8.4 18.8 4.9 7.9 5.6 42.5 25.8 8.2 17.8 13.4 7.7 24.8 8.1 6.6 15.8 68.1 12.1 38.1 5.9 8.6 12.6 24.5 32.1 47.2 15.7 12.6 7.3 11.5 14.7 4.7 29.2 15.3 19.5 11.2 27.3 3.9 58.5 11.4 3.3 24.3 54.9 44.4 15.8 2.1 45.4 17.4 20.3 3.2 8.8 13.7 31.3 8.8 11.1 1.1 47.5 11.9 20.6 4.8 41.2 4.2 97.2 21.6 11.3 11.8 17.3 12.3 13.7 15.5 22.8 12.7 22.5 6.8 3.5 1.9 15.4 3.1 8.2 9.3 17.1 1.4 0.0 2.9 15.3 2.0 7.7 1.7 8.6 1.5 2.1 16.1 2.0 0.7 0.9 0.5 1.6 7.0 6.3 5.5 2.7 7.6 8.5 7.7 10.1 7.1 7.0 8.5 7.3 8.0 8.2 7.9 7.7 3.2 28.9 24.3 27.1 7.3 6.0 23.3 17.0 25.0 0.0 20.8 16.0 25.9 11.5 19.9 3.7 0.0 85.8 1.7 59.5 11.7 13.5 0.4 4.9 3.5 4.9 10.2 1.3 0.3 4.3 11.7 6.5 21.9 7.7 22.2 24.5 4.2 44.4 21.9 0.0 0.3 20.6 2.0 9.8 11.0 1.6 26.8 11.0 3.6 17.8 12.7 6.1 5.2 3.5 0.5 5.7 53.1 14.3 2.6 3.5 78.2 128.4 14.6 0.2 0.0 2.7 5.9 0.2 2.2 5.4 7.0 81.0 4.1 12.1 25.8 14.0 ACSM2A "A-923A4.1, ACSM2, MGC150530" ENSG00000183747 "Acyl-CoA synthetase medium chain family member 2A" Q08AH3 16 20451461-20487669 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 1182 "kidney: 277.2;liver: 363.3" "Group enriched" "Detected in some" 17 "Hepatocytes: 708.7;Proximal tubular cells: 372.5" "Group enriched" "Detected in some" 479 "liver cancer: 22.7;renal cancer: 25.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "Hep G2: 1.9" HPA057699 Supported NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA057699: AB_2683506" "unprognostic (1.17e-4)" "prognostic favorable (1.41e-5)" "unprognostic (5.25e-1)" "unprognostic (2.42e-1)" "unprognostic (9.28e-3)" "unprognostic (1.52e-1)" "unprognostic (5.10e-1)" "unprognostic (2.09e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 277.2 363.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.0 4.5 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.4 21.5 0.0 7.3 0.0 0.0 0.0 0.0 31.3 0.0 0.0 0.0 0.0 2.7 0.0 13.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 17.2 708.7 0.0 0.0 0.2 0.0 0.0 18.3 0.0 0.2 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 372.5 0.0 0.0 0.0 0.5 0.1 0.2 0.1 0.0 0.1 0.3 1.7 0.0 0.0 0.1 ACSM2B "ACSM2, HXMA, HYST1046" ENSG00000066813 "Acyl-CoA synthetase medium chain family member 2B" Q68CK6 16 20536226-20576427 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 173 "kidney: 414.1;liver: 523.5" "Group enriched" "Detected in some" 20 "Hepatocytes: 1036.1;Proximal tubular cells: 441.9" "Group enriched" "Detected in some" 449 "liver cancer: 30.9;renal cancer: 17.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.9;Hep G2: 5.5;U-937: 1.9" HPA057699 Supported NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA057699: AB_2683506" "unprognostic (1.34e-2)" "prognostic favorable (3.31e-4)" "unprognostic (7.13e-2)" "unprognostic (2.29e-1)" "unprognostic (6.67e-2)" "unprognostic (1.24e-1)" "unprognostic (1.15e-1)" "unprognostic (2.22e-2)" 0.4 0.5 0.4 0.0 1.0 0.2 0.3 2.7 1.6 0.1 0.1 0.8 0.3 0.3 0.3 0.3 0.4 0.5 0.6 0.6 0.8 414.1 523.5 0.4 0.2 0.7 0.5 0.4 0.2 0.2 0.1 0.1 0.7 0.2 0.0 0.5 0.1 0.0 0.9 0.8 0.1 0.1 0.1 0.3 0.6 0.9 0.4 0.1 1.0 0.0 0.1 0.0 0.1 0.8 0.5 0.0 2.9 0.7 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.7 0.5 0.0 1.4 0.0 0.4 0.4 0.0 0.0 0.0 0.5 0.4 0.1 0.7 5.5 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.5 0.0 0.0 0.4 0.3 0.5 0.6 0.7 0.0 0.0 0.6 0.1 0.0 0.1 0.9 0.5 1.4 0.0 0.5 0.1 1.1 0.2 0.0 0.0 0.5 0.0 0.4 0.3 0.2 0.3 0.2 1.9 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 1.0 2.7 1.6 0.6 0.8 0.7 0.5 0.7 0.1 0.4 0.8 0.5 0.0 0.0 0.0 6.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.3 28.6 0.0 7.3 0.0 0.0 0.0 0.2 35.2 0.1 0.8 0.0 0.0 2.2 1.8 24.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 24.7 1036.1 0.1 0.0 0.0 0.0 0.0 23.2 0.4 0.7 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 441.9 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.0 0.1 2.7 0.1 0.0 0.0 ACSM5 FLJ20581 ENSG00000183549 "Acyl-CoA synthetase medium chain family member 5" Q6NUN0 16 20409534-20441336 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 276.6" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 237.8" "Group enriched" "Detected in some" 7 "liver cancer: 20.5;renal cancer: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 5.3;ASC TERT1: 11.5;HSkMC: 13.8;U-87 MG: 8.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA041435 Uncertain Uncertain Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA041435: AB_10961121" "unprognostic (1.01e-1)" "unprognostic (1.61e-3)" "unprognostic (3.73e-2)" "unprognostic (1.98e-2)" "unprognostic (1.03e-1)" "unprognostic (1.59e-2)" "unprognostic (1.84e-2)" "unprognostic (4.64e-3)" "unprognostic (1.64e-1)" "unprognostic (2.01e-2)" "unprognostic (2.15e-2)" "unprognostic (2.33e-1)" "unprognostic (5.11e-3)" "unprognostic (2.09e-2)" "unprognostic (3.85e-2)" "unprognostic (2.78e-2)" "unprognostic (1.57e-1)" 25.5 2.5 7.1 0.6 5.2 0.6 10.7 4.7 5.0 2.8 3.0 3.7 0.8 1.2 7.1 1.0 1.7 2.3 3.3 5.5 7.9 25.4 276.6 2.1 1.9 6.3 6.8 0.8 0.6 1.0 0.5 1.4 6.8 0.6 1.2 0.5 0.9 0.9 13.9 2.3 1.9 1.0 6.7 4.6 3.4 0.9 8.2 0.7 4.2 1.7 0.7 1.1 2.2 8.2 0.0 0.0 0.1 0.1 5.3 11.5 0.0 0.1 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.0 13.8 0.0 0.8 0.1 0.2 0.0 0.0 0.1 0.5 1.6 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 2.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 8.5 0.1 0.0 0.1 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 7.1 5.2 4.7 5.0 5.5 7.9 6.3 6.8 6.8 6.7 8.2 8.2 0.4 0.0 0.0 1.0 0.5 0.0 0.1 0.0 0.0 0.0 0.8 0.4 3.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.5 0.5 0.0 0.3 1.2 0.0 13.5 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.3 6.1 237.8 3.7 0.0 0.2 0.0 0.0 11.7 1.5 0.8 9.3 3.5 0.0 7.5 1.3 0.9 0.0 1.5 0.1 0.0 0.0 6.0 0.0 0.2 0.0 52.1 0.0 0.1 0.0 11.3 0.3 0.2 0.3 0.1 0.6 0.0 0.7 0.9 0.1 0.2 ACY1 ENSG00000243989 "Aminoacylase 1" Q03154 3 51983340-51989197 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 9 "intestine: 181.5;kidney: 449.9;liver: 274.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 31.6;Gastric mucus-secreting cells: 32.6;Proximal enterocytes: 144.8;Proximal tubular cells: 92.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 128.0" "CAB003695, HPA036174, HPA036175" Enhanced NA NA 23000000 "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB003695: AB_425286, HPA036174: AB_2674988, HPA036175: AB_2674989" "unprognostic (4.28e-2)" "unprognostic (1.89e-1)" "unprognostic (2.10e-1)" "unprognostic (2.48e-3)" "unprognostic (3.15e-1)" "unprognostic (6.51e-2)" "unprognostic (2.82e-2)" "unprognostic (1.47e-1)" "unprognostic (1.05e-2)" "unprognostic (6.08e-2)" "unprognostic (2.36e-2)" "unprognostic (2.70e-2)" "prognostic favorable (2.93e-4)" "unprognostic (3.57e-1)" "unprognostic (3.75e-1)" "unprognostic (7.88e-2)" "prognostic favorable (6.77e-4)" 19.2 24.0 5.6 7.3 5.7 8.8 20.7 6.4 7.3 13.9 11.6 30.6 181.5 4.3 21.8 10.7 13.0 10.7 14.5 5.1 6.0 449.9 274.9 9.2 7.2 6.5 5.9 4.8 8.7 28.2 4.7 9.7 6.6 14.3 30.5 1.9 16.4 11.1 20.2 8.2 138.2 6.9 6.7 8.1 23.6 3.2 6.1 5.1 21.0 34.6 9.2 12.5 7.1 6.6 15.9 26.2 13.2 34.1 28.9 39.4 40.5 12.6 28.2 29.4 14.9 41.2 67.9 7.2 12.2 22.0 13.2 20.0 14.7 81.2 11.5 21.8 10.7 25.3 13.9 128.0 49.7 19.8 21.0 48.0 67.2 25.4 69.1 25.8 11.5 14.6 47.1 23.9 29.9 35.2 0.6 38.9 23.4 92.1 39.3 8.0 14.1 63.5 74.5 50.8 16.9 18.2 12.6 62.6 29.5 7.5 42.3 27.9 7.1 22.0 21.9 24.8 18.8 61.7 16.9 12.1 28.1 42.9 29.0 9.1 15.7 0.4 10.7 15.1 5.7 7.4 2.6 4.5 21.2 6.1 4.1 4.7 0.0 20.4 6.4 2.8 3.8 9.7 5.6 5.7 6.4 7.3 5.1 6.0 6.5 5.9 6.6 6.7 6.1 6.6 0.5 3.2 3.2 0.0 4.9 0.6 1.0 1.9 17.1 0.2 2.7 1.3 0.2 1.5 2.5 5.5 0.0 3.9 0.3 31.6 9.8 16.6 0.2 0.2 0.9 0.9 2.4 15.8 0.0 8.3 4.5 4.3 32.6 0.6 7.0 0.2 1.1 13.1 1.9 0.0 0.0 11.2 4.1 1.9 0.3 0.8 0.6 4.2 0.0 0.0 9.3 0.8 1.0 0.0 0.0 16.4 23.3 0.0 14.9 0.6 144.8 92.0 1.7 1.1 0.0 0.6 2.0 0.1 0.2 18.5 0.4 4.1 2.6 1.0 14.5 0.4 ACY3 "ACY-3, HCBP1, MGC9740" ENSG00000132744 "Aminoacylase 3" Q96HD9 11 67642555-67650730 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 77.7;kidney: 58.2;liver: 33.8;pancreas: 22.2" "Group enriched" "Detected in many" 8 "Proximal enterocytes: 255.7;Proximal tubular cells: 437.6" "Cancer enhanced" "Detected in many" "renal cancer: 24.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 34.1" "Group enriched" "Detected in many" 5 "dendritic cells: 8.7;monocytes: 34.1" "Cell line enhanced" "Detected in some" "CACO-2: 9.6;CAPAN-2: 15.3;Daudi: 57.7;OE19: 15.3;RPMI-8226: 9.8" "Low region specificity" "Detected in all" "HPA039219, HPA048187" Enhanced NA NA 13000 "Cluster 51: Monocytes - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA039219: AB_10671872, HPA048187: AB_2680306" "unprognostic (8.37e-3)" "unprognostic (1.29e-1)" "unprognostic (1.04e-1)" "prognostic favorable (4.80e-4)" "unprognostic (1.07e-1)" "unprognostic (1.99e-2)" "unprognostic (1.38e-2)" "unprognostic (1.43e-1)" "unprognostic (7.37e-4)" "unprognostic (2.44e-3)" "unprognostic (1.15e-1)" "unprognostic (3.21e-1)" "unprognostic (2.63e-3)" "unprognostic (1.07e-1)" "unprognostic (8.24e-2)" "unprognostic (2.68e-2)" "unprognostic (1.48e-3)" 0.1 0.1 4.0 4.2 3.0 1.4 0.9 3.6 3.5 10.5 2.0 6.7 77.7 0.5 0.8 0.8 0.9 1.9 0.0 4.1 5.0 58.2 33.8 0.2 7.0 5.0 3.5 0.2 22.2 0.4 0.3 0.2 4.3 0.6 4.5 0.0 2.4 0.4 0.0 0.2 70.8 0.3 5.7 1.4 11.9 0.1 5.1 1.9 0.1 0.0 8.9 0.3 0.1 4.6 0.2 1.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 9.6 15.3 57.7 0.6 0.0 1.4 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 5.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.5 0.0 0.1 2.1 2.5 0.0 15.3 0.0 1.8 0.0 9.8 0.0 0.0 0.0 0.1 0.3 1.3 0.1 0.0 0.1 2.8 0.2 0.0 0.1 0.0 0.0 0.0 0.1 1.0 0.0 6.4 0.5 0.0 0.7 0.0 0.2 7.6 0.7 1.3 0.4 0.2 3.8 1.4 1.3 0.9 0.0 3.9 34.1 8.7 0.0 1.9 4.0 3.0 3.6 3.5 4.1 5.0 5.0 3.5 4.3 5.7 5.1 4.6 0.1 0.0 1.7 0.0 4.7 0.0 0.1 0.7 0.0 0.0 1.6 2.2 0.5 8.6 1.6 22.0 0.0 0.2 0.1 9.2 31.3 4.1 0.0 0.5 0.2 0.1 1.2 0.0 0.0 10.4 0.3 0.1 19.4 0.9 0.0 0.0 0.0 25.3 2.2 0.0 0.0 40.8 0.0 0.6 0.9 0.0 0.0 3.0 5.4 10.3 0.4 0.0 0.0 0.0 0.0 5.7 10.6 0.0 3.3 0.5 255.7 437.6 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 2.7 0.1 14.7 0.9 ADAMTS19 ENSG00000145808 "ADAM metallopeptidase with thrombospondin type 1 motif 19" 5 129460281-129738683 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 10 "brain: 3.3;cervix: 10.2;endometrium 1: 9.8;placenta: 3.7;smooth muscle: 5.9" "Group enriched" "Detected in some" 4 "Excitatory neurons: 82.6;Inhibitory neurons: 79.7;Oligodendrocytes: 31.8" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.7;testis cancer: 1.2" "Region enhanced" "Detected in some" "basal ganglia: 3.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "MCF7: 15.9;SH-SY5Y: 34.8" "Region enriched" "Detected in single" 5 "olfactory bulb: 2.6" "Low region specificity" "Detected in many" "HPA056171, HPA058438" Uncertain Approved Vesicles,Midbody "Secreted to extracellular matrix" Yes NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Midbody" "HPA056171: AB_2683054, HPA058438: AB_2683718" "unprognostic (1.14e-1)" "unprognostic (1.42e-1)" "unprognostic (1.01e-1)" "unprognostic (1.10e-3)" "unprognostic (1.09e-1)" "unprognostic (6.49e-2)" "unprognostic (3.93e-2)" "unprognostic (4.17e-2)" "unprognostic (5.99e-3)" "unprognostic (5.17e-1)" "unprognostic (1.14e-1)" "unprognostic (5.88e-2)" "unprognostic (3.06e-2)" 0.0 0.6 1.0 0.0 3.3 0.0 0.0 0.0 1.5 10.2 0.1 0.2 0.1 9.8 0.0 0.2 0.2 0.0 0.2 0.8 0.2 0.3 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.1 0.0 3.7 0.0 0.1 0.3 0.5 0.3 0.0 0.5 0.0 0.1 5.9 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.3 0.1 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 15.9 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 34.8 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.3 0.0 1.5 0.8 0.2 0.0 0.5 0.0 0.0 0.3 0.6 0.1 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 1.4 0.0 0.0 1.8 0.0 15.6 0.0 0.3 0.0 0.0 1.5 0.5 8.9 0.2 0.0 0.0 82.6 0.2 0.7 1.0 0.0 0.7 0.0 0.0 0.0 0.0 1.7 0.0 79.7 0.1 0.0 0.0 0.3 0.7 0.0 0.1 0.0 1.0 0.0 1.1 0.0 12.5 31.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.4 0.1 0.1 0.0 5.2 0.1 0.1 0.3 0.0 ADGRL4 "ELTD1, ETL" ENSG00000162618 "Adhesion G protein-coupled receptor L4" Q9HBW9 1 78889764-79282124 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 73.1" "Group enriched" "Detected in many" 5 "Adipocytes: 559.9;Endothelial cells: 276.0;Hepatic stellate cells: 287.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "hTERT-RPE1: 101.2;HUVEC TERT2: 330.0;TIME: 379.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025229 Supported NA NA 3800000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA025229: AB_10602493" "unprognostic (2.67e-1)" "unprognostic (2.17e-1)" "unprognostic (2.05e-2)" "unprognostic (2.58e-1)" "unprognostic (5.32e-2)" "unprognostic (8.11e-3)" "unprognostic (2.01e-1)" "unprognostic (1.23e-1)" "unprognostic (7.52e-2)" "unprognostic (2.38e-1)" "unprognostic (2.57e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (5.32e-3)" "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (3.85e-3)" 73.1 8.2 7.7 9.7 8.2 0.7 64.0 8.5 13.8 22.1 7.0 9.3 4.7 16.3 6.2 9.0 12.1 22.4 24.2 8.0 8.0 15.2 14.3 18.0 9.9 9.1 7.7 4.8 4.7 9.7 5.1 22.5 9.1 9.4 6.3 3.0 7.9 8.9 14.2 9.0 8.6 27.6 7.6 39.8 8.0 6.7 9.8 4.6 20.8 23.6 7.1 24.0 10.4 8.4 0.0 0.0 25.7 0.2 7.3 24.7 0.0 7.8 7.7 0.5 0.3 0.8 0.2 0.2 0.6 22.5 0.0 0.0 0.1 0.0 5.0 0.0 0.0 0.5 0.7 0.1 25.3 0.0 0.3 17.8 0.4 55.7 0.3 101.2 330.0 0.2 0.4 2.5 7.0 0.0 0.0 1.0 0.4 0.2 0.4 0.2 0.0 0.0 61.1 3.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 379.3 0.2 5.8 2.0 0.0 0.8 0.5 0.1 0.3 0.5 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 7.7 8.2 8.5 13.8 8.0 8.0 9.1 7.7 9.1 7.6 9.8 8.4 559.9 0.0 6.0 0.3 1.2 0.0 0.4 0.0 4.6 0.0 1.8 2.5 7.6 5.7 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.2 45.3 0.8 1.5 276.0 0.0 2.7 1.5 0.2 0.0 10.2 0.0 3.8 0.0 0.0 287.7 3.5 0.6 1.7 1.0 0.0 0.0 19.2 0.0 57.9 0.6 1.5 0.0 72.1 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.4 1.2 1.3 0.0 0.0 0.0 0.4 0.0 5.1 5.7 7.2 1.8 1.0 0.0 0.0 1.1 5.4 0.0 0.7 ADH6 ADH-5 ENSG00000172955 "Alcohol dehydrogenase 6 (class V)" P28332 4 99202638-99219537 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 703.8" "Group enriched" "Detected in some" 6 "Hepatocytes: 325.5;Proximal tubular cells: 92.4" "Cancer enriched" "Detected in many" 18 "liver cancer: 46.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "Hep G2: 44.7" "Not detected" "Not detected" "HPA067946, HPA069081" Enhanced NA NA 3400000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA067946: AB_2732776, HPA069081: AB_2732127" "unprognostic (1.38e-2)" "unprognostic (1.83e-2)" "unprognostic (5.82e-2)" "unprognostic (1.49e-3)" "unprognostic (8.49e-2)" "unprognostic (1.08e-1)" "unprognostic (5.11e-3)" "unprognostic (2.40e-1)" "unprognostic (3.60e-2)" "unprognostic (1.35e-1)" "unprognostic (9.72e-3)" "unprognostic (1.67e-1)" "unprognostic (3.66e-3)" "unprognostic (1.35e-1)" "unprognostic (2.43e-1)" "unprognostic (8.74e-3)" "unprognostic (3.86e-3)" 0.2 0.0 0.1 0.6 0.0 0.0 0.1 0.0 0.0 0.2 0.0 8.2 41.5 0.3 0.0 0.3 9.2 7.7 0.0 0.0 0.0 52.3 703.8 0.2 0.2 0.1 0.2 0.0 0.3 0.0 0.0 0.2 0.1 0.1 8.6 0.0 0.0 0.1 0.0 1.8 22.6 0.3 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.5 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 44.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.1 9.0 0.1 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.3 0.0 0.0 0.5 0.0 0.7 0.5 0.1 0.5 0.0 0.0 0.0 0.0 0.3 15.7 1.1 5.5 0.0 0.0 0.0 7.8 7.9 0.3 0.0 11.2 0.3 0.4 12.1 0.0 0.1 0.2 0.0 0.1 0.0 0.4 0.0 0.0 7.1 325.5 0.0 0.0 0.1 8.9 8.2 5.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.2 0.0 0.0 0.0 31.1 92.4 15.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.9 0.0 12.7 0.1 ADM2 "AM2, FLJ21135" ENSG00000128165 "Adrenomedullin 2" Q7Z4H4 22 50481543-50486440 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 8.3;pancreas: 15.5;thyroid gland: 11.6" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 10.0;Gastric mucus-secreting cells: 7.1;Intestinal goblet cells: 7.1;Pancreatic endocrine cells: 9.4;Proximal enterocytes: 7.4;Proximal tubular cells: 28.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 37.1;hTCEpi: 23.8;Karpas-707: 38.2;SK-MEL-30: 25.9;U-266/70: 25.6" "Not detected" "Not detected" "Secreted to blood" NA NA 61300 "Cluster 25: Pancreas - Digestion" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.30e-2)" "unprognostic (4.96e-2)" "unprognostic (6.43e-2)" "unprognostic (1.45e-1)" "unprognostic (2.67e-1)" "unprognostic (3.15e-1)" "unprognostic (4.62e-3)" "unprognostic (7.26e-3)" "unprognostic (1.50e-1)" "unprognostic (3.44e-1)" "unprognostic (7.20e-2)" "unprognostic (9.41e-2)" "unprognostic (7.30e-3)" "unprognostic (1.17e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.72e-4)" "unprognostic (1.06e-2)" 0.3 0.2 0.2 1.7 0.3 0.4 0.4 0.6 0.4 0.9 0.0 1.1 3.7 0.1 1.7 3.0 0.2 1.2 0.1 0.1 0.1 8.3 3.8 0.8 2.6 0.2 0.2 0.0 15.5 0.3 0.4 0.2 0.2 2.6 0.6 0.0 5.6 0.4 0.0 0.4 2.9 0.2 0.0 1.1 4.0 0.6 0.4 1.0 11.6 0.0 1.9 0.3 0.3 0.2 1.8 0.3 0.5 2.0 1.2 2.1 7.0 9.1 0.8 1.3 2.9 3.9 1.5 0.0 1.3 7.9 1.5 1.4 2.0 1.2 0.5 17.3 0.0 0.1 0.5 2.8 37.1 3.8 2.5 7.5 23.8 4.1 8.6 0.1 0.1 10.1 2.4 38.2 0.3 5.8 0.3 0.7 1.2 10.7 5.7 0.0 0.0 15.1 1.7 0.2 1.0 4.0 0.1 5.5 25.9 1.2 7.6 12.2 0.0 0.0 8.1 0.0 0.0 25.6 4.2 5.0 0.3 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.6 0.4 0.1 0.1 0.2 0.2 0.2 0.0 0.4 0.2 0.2 0.0 3.0 0.0 2.5 0.0 0.9 1.0 0.0 0.0 3.6 1.8 1.4 1.5 0.5 0.0 0.0 0.1 0.6 3.9 3.9 2.6 0.0 0.5 0.4 0.3 1.2 0.0 0.0 10.0 0.7 0.2 7.1 1.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 7.1 0.0 0.0 0.3 0.2 0.0 0.4 1.8 0.0 0.6 0.0 1.0 0.0 0.0 9.4 1.4 0.0 3.1 2.0 7.4 28.1 0.1 0.0 0.0 1.1 0.7 0.2 1.0 0.0 0.4 1.0 1.2 0.0 1.1 0.9 AFP "FETA, HPAFP" ENSG00000081051 "Alpha fetoprotein" P02771 4 73431138-73456174 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "liver: 3.7" "Group enriched" "Detected in some" 10 "Hepatocytes: 107.5;Proximal tubular cells: 101.6" "Cancer enriched" "Detected in some" 4 "liver cancer: 208.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 192 "Hep G2: 2165.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010607, HPA023600, CAB024283, CAB025339" Approved Approved "Golgi apparatus,Cytosol" "Secreted to blood" NA NA 3010000 150000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" Cytosol "CAB024283: AB_2650473, CAB025339: , HPA010607: AB_1078141, HPA023600: AB_1844769" "unprognostic (4.69e-1)" "unprognostic (1.87e-1)" "unprognostic (3.34e-3)" "unprognostic (1.48e-1)" "unprognostic (1.48e-3)" "unprognostic (2.95e-2)" "unprognostic (3.35e-1)" "unprognostic (1.54e-1)" "unprognostic (3.81e-2)" "unprognostic (1.01e-1)" "unprognostic (1.25e-1)" "unprognostic (1.63e-6)" "unprognostic (1.98e-2)" "unprognostic (5.80e-2)" "unprognostic (1.14e-1)" 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2165.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 1.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 9.7 5.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.1 7.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 2.7 2.8 0.3 0.0 0.1 0.0 0.1 2.5 107.5 2.3 0.0 0.1 0.1 0.0 3.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.9 101.6 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 1.5 0.2 0.1 0.2 0.0 AGMAT FLJ23384 ENSG00000116771 Agmatinase Q9BSE5 1 15571699-15585051 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Putrescine biosynthesis, Spermidine biosynthesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 133.9;liver: 62.1;skeletal muscle: 34.2" "Cell type enriched" "Detected in many" 7 "Proximal tubular cells: 306.8" "Group enriched" "Detected in all" 5 "colorectal cancer: 18.5;liver cancer: 25.3;renal cancer: 11.2;stomach cancer: 11.1" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 4.1;T-cells: 8.4" "Cell line enhanced" "Detected in many" "CACO-2: 36.7;Hep G2: 92.6;RPMI-8226: 22.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA026443, HPA028321" Enhanced NA NA 240000 "Cluster 20: T-cells - T-cell receptor" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA026443: AB_1844644, HPA028321: AB_10600779" "unprognostic (2.27e-2)" "unprognostic (3.45e-1)" "unprognostic (1.79e-3)" "unprognostic (3.60e-2)" "unprognostic (8.72e-2)" "unprognostic (6.66e-3)" "unprognostic (9.48e-2)" "unprognostic (1.19e-2)" "unprognostic (2.06e-2)" "unprognostic (2.37e-2)" "unprognostic (1.13e-2)" "unprognostic (2.35e-1)" "prognostic favorable (5.13e-4)" "unprognostic (4.43e-3)" "unprognostic (2.44e-1)" "unprognostic (1.33e-1)" "unprognostic (2.45e-2)" 0.4 1.1 1.3 3.2 1.2 1.0 0.3 1.6 1.5 0.5 1.1 9.2 17.9 0.5 0.3 0.5 0.3 0.5 0.1 1.1 1.3 133.9 62.1 0.2 4.0 0.7 0.6 0.1 0.6 2.2 0.3 0.2 0.8 0.5 6.8 0.4 4.6 0.1 34.2 0.4 13.4 0.7 0.4 1.6 1.8 0.7 0.9 2.1 0.5 6.1 4.1 0.8 0.1 1.2 7.7 6.3 0.5 0.3 0.1 0.8 0.2 1.3 1.4 0.8 0.5 36.7 5.1 0.1 0.2 0.9 0.2 0.2 0.0 0.0 0.9 7.6 0.1 5.2 5.1 92.6 0.9 4.0 0.2 0.9 0.4 2.4 0.0 0.6 0.7 0.1 0.1 10.3 1.9 8.6 0.2 4.0 8.1 6.5 3.7 0.1 0.0 22.3 0.2 2.2 1.5 1.1 10.9 0.4 1.3 0.4 1.5 8.2 1.1 0.3 0.3 2.1 0.1 0.3 6.1 5.0 0.4 0.1 0.2 1.2 0.3 0.2 2.1 0.3 2.6 4.1 4.5 2.4 0.2 2.7 8.4 5.0 1.4 0.5 0.2 0.4 6.4 2.0 1.3 1.2 1.6 1.5 1.1 1.3 0.7 0.6 0.8 0.4 0.9 1.2 0.2 0.0 0.0 1.0 5.9 0.3 1.7 0.5 0.0 1.3 0.5 0.9 0.6 2.8 0.3 3.7 0.0 0.9 0.5 7.4 31.3 1.1 9.4 1.2 1.1 0.6 1.2 2.1 1.9 0.9 0.8 0.7 5.1 2.1 0.0 1.4 1.8 42.5 1.1 3.3 2.2 9.6 2.0 2.9 0.8 4.2 0.3 2.0 1.8 3.7 1.9 1.0 5.2 0.5 0.4 2.3 6.0 0.0 2.0 1.7 27.0 306.8 1.4 2.4 0.0 4.7 0.5 1.6 3.5 1.2 0.6 0.8 5.0 3.4 18.9 3.0 AGMO "FLJ16237, TMEM195" ENSG00000187546 "Alkylglycerol monooxygenase" Q6ZNB7 7 15200317-15562015 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 122.5" "Cell type enhanced" "Detected in some" "Hepatocytes: 83.0;Oligodendrocyte precursor cells: 33.7;Oligodendrocytes: 38.5;Proximal enterocytes: 30.5;Proximal tubular cells: 16.9" "Cancer enriched" "Detected in many" 5 "liver cancer: 15.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.4" "Cell line enhanced" "Detected in some" "HSkMC: 3.5;Karpas-707: 7.7;NTERA-2: 3.5;SCLC-21H: 3.2;TIME: 4.0;WM-115: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057900 Uncertain Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 17: WM-115 - Nervous system development" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA057900: " "unprognostic (2.82e-1)" "unprognostic (9.28e-2)" "unprognostic (5.60e-3)" "unprognostic (1.44e-4)" "unprognostic (7.52e-2)" "unprognostic (1.07e-2)" "unprognostic (3.61e-2)" "unprognostic (6.56e-2)" "unprognostic (3.31e-1)" "unprognostic (3.35e-1)" "unprognostic (4.18e-3)" "unprognostic (3.24e-1)" "unprognostic (1.64e-1)" "unprognostic (2.04e-2)" "unprognostic (3.45e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" 2.8 0.1 0.9 0.6 2.4 0.1 1.8 0.7 1.9 0.1 0.1 1.2 9.7 0.1 14.5 0.1 0.1 3.6 0.4 0.7 1.4 8.9 122.5 0.2 0.5 1.5 1.4 0.1 0.1 0.0 0.4 0.8 1.5 0.0 0.6 0.1 0.2 0.1 0.3 0.2 14.9 0.1 0.9 0.0 0.3 3.0 1.8 0.2 0.4 0.4 0.1 1.2 0.1 4.1 0.0 2.2 0.0 1.9 0.2 2.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.1 3.5 0.0 0.0 0.0 0.0 1.2 0.0 0.7 3.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 4.0 1.3 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 15.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.9 2.4 0.7 1.9 0.7 1.4 1.5 1.4 1.5 0.9 1.8 4.1 10.0 0.0 0.0 6.8 0.3 0.1 0.1 0.7 0.0 0.0 0.2 0.3 0.1 11.5 0.4 3.7 0.0 0.1 0.1 0.5 0.0 0.0 1.3 0.3 0.1 1.2 1.8 2.7 1.3 0.0 0.2 1.2 0.0 0.0 0.0 0.0 1.1 83.0 0.1 0.0 1.7 0.4 0.0 1.6 0.5 1.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 33.7 38.5 0.9 0.1 0.0 0.0 0.0 30.5 16.9 0.3 0.0 6.6 0.4 2.4 1.7 6.4 0.1 0.0 0.1 0.2 0.1 0.6 0.0 AGXT "AGT, AGT1, AGXT1, PH1, SPAT, SPT" ENSG00000172482 "Alanine--glyoxylate and serine--pyruvate aminotransferase" P21549 2 240868824-240880502 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 315 "liver: 2199.2" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 2037.9" "Cancer enriched" "Detected in some" 425 "liver cancer: 253.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "Hep G2: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035370, HPA035371" Enhanced Supported Vesicles NA NA 4700000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA035370: AB_10673218, HPA035371: AB_2674593" "unprognostic (3.14e-2)" "unprognostic (2.58e-1)" "unprognostic (3.37e-4)" "unprognostic (1.04e-1)" "unprognostic (1.23e-2)" "unprognostic (9.56e-2)" "prognostic favorable (5.92e-5)" "unprognostic (8.28e-2)" "unprognostic (2.77e-1)" "unprognostic (5.39e-2)" "unprognostic (1.55e-1)" "unprognostic (7.57e-3)" "unprognostic (2.54e-1)" "unprognostic (9.22e-2)" "unprognostic (1.37e-1)" "unprognostic (3.26e-2)" 0.5 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 6.9 2199.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 2.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.3 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 44.3 0.1 7.3 0.0 0.7 0.0 7.6 23.5 0.1 0.1 0.2 0.0 2.8 9.0 128.4 0.0 1.7 26.7 0.4 0.0 0.4 0.0 0.0 52.5 2037.9 0.2 0.0 0.0 8.1 4.1 53.5 0.0 1.6 0.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 12.8 0.4 0.0 0.8 1.9 343.9 0.1 0.0 0.0 2.7 0.1 0.1 0.0 0.0 0.0 1.9 5.2 0.1 1.5 0.4 AGXT2 AGT2 ENSG00000113492 "Alanine--glyoxylate aminotransferase 2" Q9BYV1 5 34998101-35048135 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 44 "kidney: 207.9;liver: 123.5" "Group enriched" "Detected in some" 5 "Hepatocytes: 105.9;Proximal tubular cells: 359.5" "Group enriched" "Detected in some" 112 "liver cancer: 9.2;renal cancer: 12.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA037382 Enhanced NA NA 13000 "Cluster 81: Kidney & Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA037382: AB_10670851" "unprognostic (2.61e-1)" "unprognostic (1.40e-2)" "prognostic favorable (7.47e-4)" "unprognostic (8.24e-2)" "unprognostic (1.28e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 207.9 123.5 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 2.8 0.0 9.2 0.0 0.0 0.0 0.0 45.0 0.0 0.0 0.0 0.1 0.1 0.0 2.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 105.9 0.0 0.0 0.2 0.6 0.0 2.4 0.0 0.0 0.3 1.6 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 1.2 0.4 0.0 0.0 6.7 359.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.3 0.0 AIFM1 "AIF, AUNX1, CMTX4, DFNX5, NAMSD, PDCD8" ENSG00000156709 "Apoptosis inducing factor mitochondria associated 1" O95831 X 130124666-130165879 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "DNA-binding, Oxidoreductase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Dwarfism, Mental retardation, Neurodegeneration, Neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 165.4;Proximal tubular cells: 326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003764, HPA030611" Enhanced Supported Mitochondria NA NA 230000 "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB003764: AB_289587, HPA030611: AB_2673549" "unprognostic (3.00e-3)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.22e-1)" "unprognostic (2.10e-2)" "unprognostic (3.15e-3)" "unprognostic (1.46e-1)" "unprognostic (1.14e-2)" "unprognostic (1.43e-1)" "unprognostic (3.11e-2)" "unprognostic (2.54e-3)" "unprognostic (2.81e-3)" "prognostic favorable (4.42e-10)" "unprognostic (1.76e-2)" "unprognostic (1.14e-1)" "unprognostic (5.04e-2)" "unprognostic (2.11e-2)" 21.0 65.2 10.5 17.6 11.2 11.8 17.8 11.9 12.8 15.7 24.7 34.3 52.9 15.3 8.9 20.8 22.1 10.1 107.7 10.9 11.6 97.3 110.6 13.9 16.2 11.3 11.0 11.9 27.8 29.7 16.2 10.3 11.4 14.8 15.9 8.5 18.6 7.6 68.9 15.2 29.9 10.1 11.2 20.3 41.2 30.3 12.1 18.5 14.7 25.2 11.0 18.4 13.4 11.6 52.8 95.4 22.6 85.2 24.1 14.6 50.0 28.6 19.0 33.5 25.2 55.8 36.4 105.0 113.3 17.5 39.3 47.2 61.3 33.3 12.7 48.2 73.4 61.6 59.1 68.9 34.0 51.5 63.5 26.1 21.7 34.5 22.0 12.1 27.2 83.4 62.6 50.7 13.1 96.7 57.6 74.5 24.4 53.6 65.1 55.6 31.7 132.7 60.8 36.6 46.0 28.2 35.5 68.0 67.5 13.2 46.0 40.8 31.7 20.5 20.4 63.9 58.7 24.2 45.0 47.5 25.3 86.4 33.4 4.1 21.0 14.1 11.8 26.6 13.1 14.6 12.8 14.6 31.7 10.3 12.7 12.6 2.4 20.7 24.8 14.7 17.9 12.4 10.5 11.2 11.9 12.8 10.9 11.6 11.3 11.0 11.4 11.2 12.1 11.6 12.6 16.0 20.1 17.0 17.1 8.7 8.2 25.0 9.1 19.3 13.0 8.3 165.4 22.8 21.2 40.5 22.9 58.0 14.2 31.6 92.0 24.9 1.8 36.7 17.3 11.5 9.6 26.3 10.8 20.5 29.0 16.4 27.0 50.4 10.8 33.1 14.3 92.3 38.0 15.2 12.1 24.0 34.6 14.4 7.4 4.9 17.4 16.8 10.6 8.4 16.6 17.2 20.6 8.0 19.6 18.0 18.9 17.3 19.2 7.9 45.6 326.1 21.3 48.1 6.6 11.3 39.3 10.2 32.0 17.1 6.8 39.7 15.8 45.9 37.2 9.8 AK4 "AK3, AK3L1" ENSG00000162433 "Adenylate kinase 4" P27144 1 65147549-65232145 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 183.5;liver: 104.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 242.6;Proximal tubular cells: 595.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.1;myeloid DC: 2.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 208.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042753, HPA049461" Enhanced Supported Mitochondria "Intracellular and membrane" NA Yes 39000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA042753: AB_2678146, HPA049461: AB_2680776" "unprognostic (3.73e-2)" "prognostic unfavorable (4.17e-4)" "unprognostic (2.25e-1)" "unprognostic (3.05e-3)" "unprognostic (1.48e-2)" "prognostic unfavorable (8.83e-4)" "unprognostic (1.16e-3)" "unprognostic (3.89e-2)" "unprognostic (4.03e-1)" "unprognostic (5.39e-2)" "prognostic unfavorable (4.34e-5)" "unprognostic (6.71e-2)" "prognostic unfavorable (4.36e-4)" "prognostic unfavorable (4.87e-4)" "unprognostic (2.69e-1)" "unprognostic (7.07e-2)" "unprognostic (7.57e-2)" 24.7 1.9 19.5 6.6 21.0 4.9 26.6 17.8 20.8 6.1 17.5 19.7 4.3 7.0 4.2 23.4 7.6 13.7 51.7 21.4 21.2 183.5 104.0 2.8 1.6 19.0 22.8 4.6 1.2 18.3 4.7 8.3 22.8 16.2 14.0 21.9 9.6 12.7 1.7 27.4 6.6 21.4 18.5 1.2 15.0 11.3 22.7 5.7 2.5 38.8 3.3 19.1 11.8 21.1 73.2 5.0 5.6 23.9 51.6 48.7 12.0 12.1 15.0 25.6 70.8 108.1 8.6 39.1 31.0 19.0 32.1 46.1 18.8 89.9 101.9 33.0 21.5 37.9 21.9 208.6 2.5 29.9 4.6 27.2 49.6 25.1 73.0 42.2 0.9 12.2 48.0 0.6 39.6 31.2 1.1 1.3 24.6 1.0 42.5 0.2 41.0 7.1 37.8 3.2 20.5 15.4 21.6 1.5 16.7 25.8 29.7 12.9 4.2 42.4 36.2 3.3 20.9 39.5 18.8 2.1 68.7 10.9 2.5 0.9 3.1 0.0 0.1 0.6 0.2 0.2 0.1 0.2 2.7 0.1 0.1 0.1 0.4 0.3 0.1 0.4 0.0 0.8 19.5 21.0 17.8 20.8 21.4 21.2 19.0 22.8 22.8 18.5 22.7 21.1 11.2 0.0 0.5 51.2 4.7 49.7 23.6 44.2 63.7 24.5 48.9 44.7 105.7 52.9 14.3 31.3 2.1 2.2 0.6 15.8 56.7 18.6 3.4 30.1 8.2 19.6 5.4 13.9 17.1 12.1 21.1 11.4 27.5 52.2 0.0 36.4 11.7 242.6 3.3 16.8 7.7 8.7 24.4 7.8 9.2 5.8 4.1 6.9 24.9 3.7 5.7 32.7 0.0 9.5 2.5 31.9 4.3 9.4 0.4 38.7 18.8 595.5 12.3 6.5 6.6 5.6 18.8 1.8 9.5 43.1 74.3 4.9 3.6 0.7 23.1 20.4 AKR7A3 ENSG00000162482 "Aldo-keto reductase family 7 member A3" O95154 1 19282573-19288770 "Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 248.9;liver: 154.6;pancreas: 288.4;stomach 1: 224.4" "Group enriched" "Detected in many" 5 "Gastric mucus-secreting cells: 348.1;Proximal enterocytes: 1132.3;Proximal tubular cells: 766.6" "Cancer enhanced" "Detected in many" "liver cancer: 36.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "OE19: 15.9;SK-BR-3: 25.0" HPA064638 Supported "Golgi apparatus,Cytosol" NA NA 1900000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "Golgi apparatus" "HPA064638: AB_2685307" "unprognostic (7.78e-2)" "unprognostic (5.07e-2)" "unprognostic (6.08e-2)" "unprognostic (1.61e-1)" "unprognostic (1.10e-2)" "unprognostic (8.84e-2)" "unprognostic (3.85e-3)" "unprognostic (7.70e-3)" "unprognostic (2.72e-1)" "unprognostic (2.50e-2)" "unprognostic (1.17e-1)" "unprognostic (2.98e-1)" "prognostic favorable (8.80e-7)" "unprognostic (4.53e-2)" "unprognostic (5.58e-2)" "unprognostic (2.85e-1)" "unprognostic (2.35e-1)" 1.6 4.0 2.3 2.6 2.4 0.3 4.2 2.8 3.2 2.3 16.7 29.2 248.9 1.4 0.4 1.8 1.8 38.0 0.6 3.3 2.6 71.1 154.6 1.0 0.4 2.7 2.9 2.6 288.4 0.3 2.2 0.2 2.6 1.9 17.4 1.5 3.5 0.3 0.4 2.6 144.8 1.4 2.5 1.3 224.4 2.1 2.9 0.1 1.8 0.1 0.2 1.0 1.6 2.6 0.5 0.0 0.5 0.3 0.5 0.2 1.8 0.1 0.1 0.2 0.1 0.5 1.9 0.2 0.3 0.4 0.0 0.8 0.0 0.0 0.0 0.2 0.5 0.2 0.7 0.8 0.2 0.2 0.2 0.3 0.3 0.3 0.0 0.2 0.0 0.3 0.2 0.3 0.1 0.7 0.5 1.7 0.3 15.9 0.6 0.7 0.1 1.6 0.0 0.1 0.9 1.4 0.3 25.0 0.6 0.1 4.1 0.5 0.4 0.3 0.2 0.9 0.3 1.2 0.3 0.3 0.5 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.3 2.4 2.8 3.2 3.3 2.6 2.7 2.9 2.6 2.5 2.9 2.6 0.4 0.0 0.0 7.5 3.3 0.8 0.7 0.2 0.6 1.0 13.8 9.5 0.8 140.2 0.3 29.5 0.0 0.5 0.5 133.3 119.3 3.9 3.5 0.5 0.4 0.8 20.8 11.2 4.1 31.8 0.3 0.5 348.1 0.4 4.5 0.9 4.2 119.0 0.3 0.0 3.6 87.6 4.1 3.5 0.0 4.7 0.3 4.4 0.0 1.9 0.1 3.6 0.0 2.5 1.9 18.3 125.0 0.4 0.8 1.2 1132.3 766.6 3.2 1.1 0.0 0.7 0.4 1.8 1.1 1.1 0.6 0.5 3.0 0.7 130.2 0.4 ALDH1L1 "10-fTHF, FDH, FTHFD" ENSG00000144908 "Aldehyde dehydrogenase 1 family member L1" O75891 3 126103562-126197994 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 369.7" "Group enriched" "Detected in many" 4 "Hepatocytes: 633.3;Proximal tubular cells: 197.4" "Cancer enriched" "Detected in many" 4 "liver cancer: 40.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 36.5;Hep G2: 78.1;Karpas-707: 82.0;RPMI-8226: 45.0;RT4: 219.1;U-266/70: 44.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036900, HPA050139" Enhanced Supported Supported Cytosol No No 3000000 "Cluster 15: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Cytosol "HPA036900: AB_10672273, HPA050139: AB_2681031" "unprognostic (5.93e-2)" "unprognostic (1.22e-1)" "unprognostic (9.12e-2)" "unprognostic (2.68e-1)" "unprognostic (1.10e-1)" "unprognostic (1.10e-1)" "unprognostic (7.12e-2)" "unprognostic (1.29e-1)" "unprognostic (3.05e-2)" "unprognostic (4.73e-2)" "unprognostic (3.05e-3)" "unprognostic (8.40e-2)" "prognostic favorable (2.42e-8)" "unprognostic (3.60e-1)" "unprognostic (1.47e-1)" "unprognostic (7.03e-3)" "unprognostic (7.93e-2)" 76.4 37.2 53.4 2.0 63.2 0.4 28.8 55.9 63.6 15.6 37.7 10.1 0.2 7.2 2.5 6.6 16.0 2.3 26.5 47.5 56.2 116.6 369.7 3.1 0.3 56.7 52.9 45.3 44.3 15.1 4.5 0.0 53.0 14.6 5.4 8.7 88.6 6.9 90.7 3.5 5.6 2.0 48.4 0.4 9.5 15.0 53.9 3.7 2.6 59.9 4.6 28.3 6.4 46.0 1.3 0.0 0.0 0.0 36.5 0.0 0.4 0.3 1.5 0.4 0.6 0.0 3.2 2.6 10.2 0.0 2.1 0.4 0.6 1.5 0.7 0.0 0.2 0.1 0.3 78.1 10.6 10.6 0.2 0.3 0.8 0.0 0.0 0.3 0.0 0.0 0.0 82.0 1.6 0.0 0.0 0.2 0.3 1.1 0.0 0.1 0.2 45.0 0.7 219.1 0.4 0.3 1.3 10.6 0.0 0.6 0.1 0.0 0.3 1.4 6.2 0.0 0.1 44.8 14.8 0.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.4 63.2 55.9 63.6 47.5 56.2 56.7 52.9 53.0 48.4 53.9 46.0 0.8 0.0 6.0 92.7 4.6 0.1 53.5 9.1 1.8 0.2 14.4 2.2 16.1 38.6 44.0 12.9 0.0 0.0 0.1 7.2 72.4 2.9 22.3 57.2 5.2 4.6 1.2 34.7 0.6 5.6 0.2 9.1 0.0 3.6 27.8 12.4 17.2 633.3 0.1 0.0 3.0 17.6 2.0 24.5 1.9 35.0 26.4 9.3 3.6 3.7 0.0 40.0 0.0 11.1 0.2 2.2 0.4 22.6 0.0 12.2 0.8 197.4 32.2 1.4 6.6 10.5 5.3 1.6 4.3 1.7 0.0 0.1 2.8 0.9 5.6 61.7 ALDH4A1 "ALDH4, P5CDh" ENSG00000159423 "Aldehyde dehydrogenase 4 family member A1" P30038 1 18871430-18902724 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Proline metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 200.4;liver: 436.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 78.0;Hepatocytes: 385.1;Proximal tubular cells: 279.4;Syncytiotrophoblasts: 86.6" "Cancer enhanced" "Detected in all" "liver cancer: 72.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Hep G2: 83.7;SK-BR-3: 85.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004645, HPA006401, HPA072759" Enhanced Supported Mitochondria NA NA 58000 "Cluster 7: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB004645: AB_425775, HPA006401: AB_1844731, HPA072759: " "unprognostic (1.17e-1)" "prognostic favorable (5.06e-4)" "unprognostic (1.38e-2)" "unprognostic (4.16e-2)" "unprognostic (3.15e-1)" "unprognostic (7.67e-2)" "unprognostic (1.28e-1)" "unprognostic (6.18e-2)" "unprognostic (1.92e-1)" "unprognostic (1.09e-2)" "unprognostic (1.02e-1)" "unprognostic (2.06e-1)" "unprognostic (4.27e-3)" "unprognostic (9.41e-3)" "unprognostic (3.83e-1)" "unprognostic (2.69e-3)" "unprognostic (9.34e-2)" 70.8 16.1 73.9 3.9 88.9 11.7 21.6 73.8 95.9 12.6 106.5 6.8 1.6 9.8 4.7 36.3 8.3 5.5 33.0 68.2 73.8 200.4 436.6 6.2 3.4 72.9 82.8 7.3 4.6 23.0 9.7 13.2 70.0 29.5 2.7 6.5 9.1 27.1 74.2 19.2 4.7 7.1 65.6 7.5 12.5 3.2 92.4 11.7 7.1 74.8 4.2 19.3 16.8 66.1 12.7 17.8 9.5 29.2 40.0 5.7 25.2 13.1 7.1 11.8 9.5 13.7 8.9 8.8 16.6 15.6 5.7 34.0 16.7 35.4 4.5 4.8 15.9 5.9 5.0 83.7 12.6 4.4 15.1 15.6 19.2 6.5 6.6 9.0 13.5 14.0 21.0 5.7 8.1 32.3 4.3 20.2 4.7 26.0 10.1 27.9 8.4 10.0 12.1 32.0 19.6 7.6 21.9 85.0 16.1 14.7 38.7 6.3 11.3 10.2 14.0 12.2 4.5 7.1 17.9 2.5 3.4 33.7 13.5 0.0 2.7 1.5 0.6 3.6 0.5 0.8 0.3 0.8 4.4 0.7 0.2 0.5 0.3 0.1 2.0 1.5 0.6 1.5 73.9 88.9 73.8 95.9 68.2 73.8 72.9 82.8 70.0 65.6 92.4 66.1 2.6 0.0 2.8 27.1 4.3 7.5 17.9 12.5 17.6 3.7 9.8 8.5 20.9 34.3 2.9 46.0 10.4 78.0 2.0 2.0 46.9 6.5 0.5 1.1 1.7 3.1 2.4 32.2 1.2 0.9 12.6 3.2 7.7 3.9 4.5 2.1 15.4 385.1 13.8 20.2 1.6 3.6 6.1 17.2 1.4 0.6 1.2 4.7 3.6 1.9 10.9 14.0 1.0 5.5 1.3 2.5 1.8 2.6 4.4 12.0 0.3 279.4 1.7 4.8 6.6 2.6 4.7 2.2 3.9 21.7 5.4 86.6 2.6 4.5 4.0 9.5 ALDH6A1 MMSDH ENSG00000119711 "Aldehyde dehydrogenase 6 family member A1" Q02252 14 74056847-74084492 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "kidney: 379.1;liver: 367.1" "Cell type enhanced" "Detected in all" "Distal tubular cells: 201.5;Hepatocytes: 523.6;Proximal tubular cells: 962.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 43.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 43.2" "Cell line enhanced" "Detected in all" "T-47d: 57.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029072, HPA029073, HPA029074, HPA029075" Enhanced Enhanced Mitochondria No No 37000 "Cluster 2: Granulocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA029072: AB_10599176, HPA029073: AB_10601877, HPA029074: AB_10601000, HPA029075: AB_10602005" "unprognostic (1.45e-1)" "unprognostic (5.38e-2)" "unprognostic (6.89e-2)" "unprognostic (6.95e-3)" "unprognostic (1.46e-1)" "unprognostic (7.93e-2)" "unprognostic (1.11e-3)" "prognostic favorable (4.22e-4)" "unprognostic (1.58e-1)" "unprognostic (9.10e-2)" "unprognostic (3.11e-2)" "unprognostic (2.13e-1)" "prognostic favorable (2.00e-15)" "unprognostic (4.59e-1)" "unprognostic (1.92e-1)" "unprognostic (6.05e-3)" "unprognostic (1.12e-1)" 38.7 14.7 58.6 4.8 66.0 3.3 14.4 58.8 59.3 17.3 61.4 15.2 26.6 11.4 9.8 9.8 12.8 9.4 40.3 51.0 54.0 379.1 367.1 9.4 5.1 63.3 54.0 28.3 23.4 37.0 6.6 7.6 55.6 25.4 15.8 15.2 19.8 16.1 27.5 6.2 23.4 9.0 56.4 5.4 24.0 17.1 69.8 5.7 28.3 34.8 5.3 11.4 7.0 62.6 8.9 7.8 11.0 23.5 39.3 19.2 17.5 6.3 11.8 6.8 11.5 17.3 10.2 10.5 13.6 13.5 5.3 4.8 24.9 7.0 14.5 9.5 3.5 5.1 8.0 19.2 45.0 2.7 2.4 28.2 12.0 8.7 20.7 17.0 12.0 23.7 8.1 14.7 4.6 36.2 7.6 4.0 8.7 32.6 5.2 15.1 11.2 14.6 9.2 5.8 4.4 7.0 21.0 21.9 5.7 18.0 57.5 9.6 3.8 7.4 9.0 11.7 2.4 9.3 18.9 10.2 9.9 3.2 7.3 29.1 6.2 43.2 6.9 4.8 10.6 7.2 7.8 8.4 9.2 6.1 9.9 7.0 2.4 9.7 4.2 5.3 6.1 4.9 58.6 66.0 58.8 59.3 51.0 54.0 63.3 54.0 55.6 56.4 69.8 62.6 15.4 38.5 60.4 24.5 11.8 9.2 26.8 10.0 20.5 20.6 28.4 18.9 81.4 67.2 22.9 66.2 4.2 31.0 7.1 18.9 201.5 11.6 23.4 26.2 27.5 27.0 16.9 28.6 5.5 3.1 14.8 25.9 34.7 90.2 7.6 27.1 87.4 523.6 17.7 11.8 10.0 39.3 8.2 26.5 8.9 19.0 28.9 13.4 24.9 1.9 15.8 98.5 9.2 12.5 23.4 4.1 16.3 48.2 8.0 27.6 55.3 962.4 15.4 17.0 13.1 25.6 16.9 11.0 4.2 25.2 7.4 30.6 11.0 10.2 35.7 17.2 ALDH8A1 ALDH12 ENSG00000118514 "Aldehyde dehydrogenase 8 family member A1" Q9H2A2 6 134917393-134950115 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 16 "kidney: 72.2;liver: 247.2" "Group enriched" "Detected in some" 4 "Hepatocytes: 142.5;Proximal tubular cells: 136.9" "Group enriched" "Detected in some" 7 "liver cancer: 26.3;renal cancer: 17.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HEK 293: 2.9;Hep G2: 2.9;K-562: 3.0;RPTEC TERT1: 3.3;U-266/70: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA026292, HPA055414" Enhanced Approved Nucleoplasm,Centrosome NA NA 110000 "Cluster 46: Basophils - DNA binding" "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Centrosome Nucleoplasm "HPA026292: AB_1844741, HPA055414: AB_2682810" "unprognostic (1.12e-1)" "unprognostic (1.48e-1)" "unprognostic (1.88e-1)" "unprognostic (1.75e-1)" "unprognostic (2.70e-2)" "unprognostic (6.32e-2)" "unprognostic (4.30e-3)" "unprognostic (1.12e-1)" "unprognostic (3.98e-2)" "unprognostic (1.64e-1)" "unprognostic (2.39e-2)" "unprognostic (3.99e-2)" "prognostic favorable (9.87e-4)" "unprognostic (1.25e-2)" "unprognostic (1.36e-1)" "unprognostic (2.36e-2)" "unprognostic (5.86e-5)" 1.3 1.3 6.4 0.7 7.1 2.4 1.2 6.9 9.8 1.5 2.2 3.3 0.8 1.2 2.1 0.8 1.0 0.9 0.7 6.5 3.8 72.2 247.2 0.9 0.6 5.3 4.4 0.5 0.9 0.4 0.8 0.5 6.2 1.7 0.8 2.8 0.8 0.8 3.6 1.7 1.1 0.9 3.1 1.3 1.2 0.5 5.4 0.7 0.6 0.3 0.6 1.9 0.9 8.3 0.1 0.5 0.8 0.5 0.2 0.1 0.6 0.2 0.2 0.0 0.5 0.2 0.3 0.1 0.2 0.0 0.1 0.6 0.6 0.0 0.4 0.6 2.9 2.0 2.1 2.9 0.3 0.8 1.0 0.8 0.9 0.2 0.4 0.6 0.2 0.8 3.0 1.1 0.1 0.0 0.9 1.0 0.2 0.2 0.3 0.0 0.2 0.2 3.3 0.4 0.8 0.2 0.1 0.0 0.5 0.2 0.3 0.2 0.2 0.2 1.6 0.6 0.8 2.8 1.0 0.5 0.3 0.7 0.2 2.5 0.3 0.3 0.4 0.1 0.1 0.4 0.4 0.2 0.0 0.4 0.3 0.3 0.8 0.8 0.1 0.4 0.5 0.3 6.4 7.1 6.9 9.8 6.5 3.8 5.3 4.4 6.2 3.1 5.4 8.3 0.3 3.2 0.6 3.6 0.8 0.0 0.2 0.2 0.0 2.6 0.7 0.9 0.6 1.5 0.7 31.3 0.0 0.2 0.3 0.1 19.6 0.2 0.1 0.4 0.4 0.7 0.0 0.0 14.3 0.0 1.7 0.4 0.0 1.6 0.0 0.5 2.5 142.5 0.1 3.3 12.9 0.1 0.0 2.5 0.3 0.0 0.0 0.8 0.0 1.0 0.7 0.3 0.0 3.0 9.6 0.0 0.1 0.0 0.3 0.1 0.0 136.9 0.0 1.8 0.0 1.2 0.5 0.0 0.0 0.0 0.4 0.0 0.9 0.5 0.2 0.1 ALDOB ENSG00000136872 "Aldolase, fructose-bisphosphate B" P05062 9 101420560-101449664 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 27 "intestine: 5736.6;kidney: 7181.0;liver: 11160.8" "Group enriched" "Detected in some" 4 "Proximal enterocytes: 20078.3;Proximal tubular cells: 7956.0" "Cancer enriched" "Detected in many" 31 "liver cancer: 1414.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 21.4;NB-4: 21.0;RPMI-8226: 28.6;SH-SY5Y: 20.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA002198, CAB020827" Enhanced NA NA 560000000 "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 24: NB-4 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB020827: , HPA002198: AB_1078129" "unprognostic (6.58e-3)" "unprognostic (2.83e-1)" "unprognostic (1.43e-3)" "unprognostic (1.03e-1)" "unprognostic (8.10e-2)" "unprognostic (1.96e-2)" "unprognostic (1.44e-3)" "unprognostic (4.34e-2)" "unprognostic (4.57e-2)" "unprognostic (2.66e-1)" "unprognostic (5.79e-2)" "unprognostic (7.48e-2)" "unprognostic (1.66e-2)" "unprognostic (2.02e-1)" "unprognostic (2.58e-1)" "unprognostic (5.19e-2)" "unprognostic (1.96e-2)" 3.3 1.4 0.4 17.0 0.7 0.0 0.7 1.0 2.3 0.2 0.0 30.1 4073.8 2.8 1.0 0.7 0.4 176.9 1.0 2.4 0.0 7181.0 11160.8 0.5 4.9 0.0 0.0 0.5 292.7 0.0 5.6 0.4 0.0 2.1 5.6 0.3 0.3 0.0 0.4 0.5 5736.6 7.0 0.0 2.0 34.3 1.1 0.0 0.7 0.3 0.0 0.8 0.1 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 21.4 0.0 0.0 0.0 0.0 0.5 0.0 4.5 1.8 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 2.2 0.0 1.0 0.0 6.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.3 0.0 0.0 0.3 21.0 0.4 0.5 0.0 0.3 4.6 28.6 0.0 0.0 4.3 20.6 2.0 0.0 0.0 0.0 0.0 0.1 1.9 0.1 1.0 7.1 0.3 0.5 0.7 2.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 1.0 2.3 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 39.4 0.0 0.0 0.3 0.0 1.1 0.0 0.0 1.1 308.8 0.8 150.8 0.0 0.0 0.0 13.5 620.3 4.9 0.0 0.0 0.4 3.6 0.0 50.8 0.5 253.3 0.1 0.0 0.0 0.3 0.0 0.0 49.2 3225.4 0.2 3.3 0.2 464.9 0.0 66.2 0.0 0.0 0.0 38.1 0.0 0.0 3.6 0.3 0.0 0.0 0.3 182.1 997.4 0.0 0.1 0.0 20078.3 7956.0 0.2 0.6 0.0 0.4 1.6 0.0 0.0 0.0 0.0 0.3 20.6 0.2 412.7 0.0 ALLC ALC ENSG00000151360 Allantoicase Q8N6M5 2 3658200-3702671 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 17 "testis: 16.5" "Cell type enriched" "Detected in some" 4 "Early spermatids: 140.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 19 "U-266/84: 6.1" "Not detected" "Not detected" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (5.47e-2)" "unprognostic (3.24e-2)" "unprognostic (2.91e-3)" "unprognostic (4.75e-1)" "unprognostic (2.17e-1)" "unprognostic (1.06e-1)" "unprognostic (9.83e-3)" "unprognostic (5.42e-2)" "unprognostic (1.74e-4)" "unprognostic (1.01e-2)" "unprognostic (2.73e-1)" 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.1 0.4 0.6 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 16.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 140.7 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 33.2 3.4 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 22.2 0.0 0.0 0.0 0.5 0.0 0.0 13.1 0.0 0.1 5.1 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 ALPL "HOPS, TNALP, TNAP, TNSALP" ENSG00000162551 "Alkaline phosphatase, biomineralization associated" P05186 1 21509397-21578410 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Biomineralization Hydrolase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 60.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 92.0;Breast myoepithelial cells: 32.4;Glandular and luminal cells: 43.3;Hepatic stellate cells: 40.7;Hepatocytes: 30.1;Proximal tubular cells: 43.9;Rod photoreceptor cells: 34.2" "Cancer enhanced" "Detected in all" "testis cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 90 "neutrophil: 379.1" "Lineage enriched" "Detected in many" 139 "granulocytes: 379.1" "Cell line enhanced" "Detected in many" "HSkMC: 176.9;hTEC/SVTERT24-B: 141.2;LHCN-M2: 103.7;NTERA-2: 41.2;SCLC-21H: 88.2;SuSa: 48.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007105, HPA008765, CAB020829" Enhanced Approved Cytosol "Intracellular and membrane" NA NA 13000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 11: Alveolar cells - Smell perception" Cytosol "CAB020829: , HPA007105: AB_1078137, HPA008765: AB_1078138" "unprognostic (3.89e-2)" "unprognostic (1.27e-1)" "unprognostic (5.57e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (7.57e-4)" "unprognostic (3.05e-3)" "unprognostic (6.50e-3)" "unprognostic (1.01e-1)" "prognostic unfavorable (7.08e-4)" "unprognostic (1.17e-2)" "unprognostic (2.48e-3)" "unprognostic (1.74e-1)" "unprognostic (7.28e-2)" "unprognostic (1.73e-2)" "unprognostic (2.27e-1)" "unprognostic (9.70e-3)" "unprognostic (2.58e-1)" 24.7 60.7 19.5 27.9 16.7 4.2 22.9 18.0 25.8 3.4 26.0 5.0 2.6 5.8 1.3 4.1 10.4 3.9 16.4 17.8 18.8 45.7 56.3 54.9 6.4 21.7 17.7 2.8 3.9 3.3 9.3 3.1 22.4 7.1 1.5 18.8 6.4 9.2 1.1 4.2 7.5 3.5 18.2 45.5 4.7 4.2 21.3 1.5 8.6 5.7 5.9 9.7 3.3 17.3 0.0 0.2 5.2 0.2 0.8 6.6 11.4 0.4 2.4 0.9 1.5 1.0 0.0 2.4 7.7 0.0 0.1 0.1 31.3 0.2 0.6 0.0 2.1 0.0 3.5 3.9 1.8 0.0 0.7 176.9 0.0 141.2 0.5 0.0 0.0 0.0 0.2 0.0 103.7 0.0 0.1 0.0 41.2 0.2 0.0 0.0 3.8 0.2 0.1 0.0 88.2 1.2 0.0 0.1 0.3 48.1 0.2 0.0 0.0 5.2 4.3 0.1 0.0 0.3 0.0 0.1 0.9 0.0 0.8 0.0 0.0 4.2 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.5 0.0 0.0 379.1 0.0 0.0 0.0 0.0 0.1 19.5 16.7 18.0 25.8 17.8 18.8 21.7 17.7 22.4 18.2 21.3 17.3 25.9 3.2 92.0 0.3 3.8 0.1 0.6 8.2 0.6 2.5 6.6 32.4 2.1 2.8 17.6 0.0 0.0 0.1 0.1 0.0 7.9 0.0 1.4 15.0 2.2 26.5 0.0 5.7 0.9 0.0 0.3 6.8 0.0 43.3 7.6 10.6 40.7 30.1 0.1 1.7 0.3 0.0 12.2 1.6 0.3 8.5 0.3 1.0 0.0 18.7 0.0 6.0 0.0 6.0 0.2 0.0 0.0 0.0 0.3 1.7 0.0 43.9 3.6 34.2 0.0 0.3 5.1 0.4 14.0 0.2 0.4 1.5 1.0 8.0 0.0 0.3 ALS2CL "DKFZp686I0110, FLJ36525, RN49018" ENSG00000178038 "ALS2 C-terminal like" Q60I27 3 46668995-46693704 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 37.5;kidney: 30.7;skin 1: 32.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Gastric mucus-secreting cells: 41.3;Respiratory ciliated cells: 46.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 31.6;HaCaT: 17.1;HBEC3-KT: 33.1;hTCEpi: 20.9;RT4: 15.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB046465, HPA048301" Uncertain NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB046465: AB_10638285, HPA048301: AB_2680346" "unprognostic (6.38e-2)" "unprognostic (5.98e-2)" "unprognostic (2.38e-3)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.86e-2)" "unprognostic (1.04e-2)" "unprognostic (1.92e-1)" "unprognostic (8.60e-2)" "unprognostic (4.28e-2)" "unprognostic (1.42e-2)" "unprognostic (4.50e-2)" "unprognostic (1.04e-1)" "unprognostic (1.98e-3)" "unprognostic (4.45e-2)" "unprognostic (5.20e-2)" "unprognostic (6.79e-2)" "unprognostic (4.14e-3)" 4.7 2.2 0.8 1.6 0.9 0.8 5.1 1.8 2.0 10.1 0.5 5.6 3.5 2.2 0.1 37.5 4.4 2.7 10.1 0.6 0.8 30.7 7.2 10.8 1.7 1.5 0.6 1.8 5.8 0.5 4.3 1.3 1.4 4.5 1.0 0.0 11.0 2.2 5.3 32.3 4.7 0.8 0.5 6.5 3.5 0.8 0.6 1.1 15.6 1.9 1.4 4.8 19.5 0.6 9.8 2.2 0.0 0.0 0.0 0.0 0.1 0.7 1.1 0.0 0.3 0.1 31.6 0.0 8.9 0.8 0.5 17.1 0.0 33.1 0.1 0.1 0.0 0.8 3.7 0.0 0.3 0.0 0.0 0.0 20.9 0.0 3.2 0.2 0.9 2.0 0.0 0.2 0.0 0.9 0.0 0.1 0.3 4.7 1.9 0.1 0.0 12.0 7.7 15.8 0.3 0.2 12.6 9.7 0.0 0.5 2.2 0.2 6.6 0.1 1.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.8 0.9 1.8 2.0 0.6 0.8 1.5 0.6 1.4 0.5 0.6 0.6 17.5 73.7 15.3 2.3 0.5 15.2 8.4 21.8 12.0 0.3 4.7 5.5 10.2 18.6 29.9 11.0 0.0 1.5 0.1 29.0 0.0 10.1 0.6 5.1 1.8 13.1 0.0 0.0 8.0 13.5 7.3 4.5 41.3 5.5 1.3 0.1 7.1 7.6 2.7 0.0 2.9 6.4 24.4 0.3 4.1 0.2 0.3 1.4 1.8 10.3 0.8 0.1 0.0 0.0 0.3 26.3 12.0 0.0 0.1 17.7 5.9 0.4 46.9 0.1 19.7 5.6 8.5 1.3 2.7 22.3 16.3 2.1 1.3 0.3 11.8 27.7 AMDHD1 MGC35366 ENSG00000139344 "Amidohydrolase domain containing 1" Q96NU7 12 95943331-95968720 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Histidine metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 60.7;skeletal muscle: 27.3" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 132.5" "Cancer enriched" "Detected in many" 14 "liver cancer: 23.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 46.6;HMC-1: 47.7;Karpas-707: 61.2;SiHa: 40.5;SK-BR-3: 46.1;U-266/70: 49.1;U-266/84: 62.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039720, HPA040149" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" No NA 1400000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "Nucleoplasm, Plasma membrane" "HPA039720: AB_10672967, HPA040149: " "unprognostic (4.81e-2)" "unprognostic (2.91e-1)" "unprognostic (1.53e-1)" "unprognostic (2.09e-2)" "unprognostic (1.80e-2)" "unprognostic (2.88e-2)" "unprognostic (2.33e-2)" "unprognostic (6.62e-3)" "unprognostic (1.06e-1)" "unprognostic (7.01e-2)" "unprognostic (3.35e-3)" "unprognostic (1.17e-1)" "unprognostic (4.63e-3)" "unprognostic (3.98e-2)" "unprognostic (1.70e-1)" "unprognostic (4.08e-3)" "unprognostic (2.61e-1)" 1.8 11.7 8.2 6.5 11.2 6.1 0.4 5.5 11.8 0.3 6.9 1.4 5.1 3.0 0.4 2.6 0.7 1.7 1.7 7.6 6.9 5.8 60.7 2.3 4.4 15.5 8.6 1.4 3.3 0.7 0.5 2.0 9.5 2.8 0.2 1.8 2.0 0.2 27.3 5.8 5.0 0.6 2.7 5.9 4.8 13.1 8.0 0.6 0.9 0.9 0.4 0.3 0.2 15.4 46.6 9.5 0.8 5.8 0.0 0.0 10.0 1.5 0.5 0.7 1.4 3.9 5.8 4.0 4.2 0.0 2.6 8.2 0.3 0.0 0.3 16.0 1.7 4.2 7.9 9.4 0.0 5.9 47.7 0.0 0.4 0.8 0.1 0.2 0.3 3.9 2.7 61.2 0.0 6.8 3.7 10.8 4.4 1.8 2.2 7.8 0.3 5.3 0.0 4.3 4.9 6.9 40.5 46.1 5.2 0.2 4.6 8.4 0.0 5.8 19.1 8.0 5.4 49.1 62.8 6.3 3.8 12.2 6.9 0.2 0.6 1.7 0.5 0.6 0.4 0.6 0.2 0.6 0.5 0.3 0.3 0.4 0.4 2.3 1.8 0.2 0.1 0.5 8.2 11.2 5.5 11.8 7.6 6.9 15.5 8.6 9.5 2.7 8.0 15.4 1.1 0.0 0.5 0.3 2.0 0.4 0.2 0.0 0.0 0.1 1.1 1.0 0.6 1.5 0.6 3.7 0.0 0.9 1.7 0.0 3.9 0.2 0.9 0.1 0.0 0.8 1.8 8.0 0.7 1.1 0.1 0.1 0.0 0.0 0.0 0.2 8.6 132.5 4.4 1.7 0.3 0.1 0.0 5.7 1.3 0.1 0.3 1.8 3.6 0.0 0.7 1.8 2.1 4.0 2.0 0.2 0.0 0.0 0.7 0.0 0.4 31.0 0.0 0.0 0.0 0.8 0.0 1.5 1.9 0.0 0.3 0.3 1.4 0.3 0.4 0.1 AMN amnionless ENSG00000166126 "Amnion associated transmembrane protein" Q9BXJ7 14 102922663-102933596 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Protein transport, Transport" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 83.5;kidney: 39.8;liver: 37.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 672.6;Intestinal goblet cells: 283.9;Paneth cells: 724.4;Proximal enterocytes: 2014.8;Proximal tubular cells: 348.9;Undifferentiated cells: 272.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.2;CACO-2: 8.1;Hep G2: 9.9;U-698: 3.4" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA000817 Approved "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "HPA000817: AB_1078146" "unprognostic (2.02e-2)" "unprognostic (1.67e-1)" "unprognostic (3.94e-3)" "unprognostic (7.39e-3)" "unprognostic (9.32e-2)" "unprognostic (1.88e-3)" "unprognostic (8.68e-2)" "unprognostic (1.62e-1)" "unprognostic (4.37e-2)" "unprognostic (2.97e-2)" "unprognostic (7.57e-2)" "unprognostic (2.43e-2)" "prognostic favorable (9.62e-5)" "unprognostic (8.02e-2)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (1.66e-1)" 1.4 0.0 0.1 1.1 0.2 0.1 0.5 0.1 0.2 1.5 0.0 33.0 43.5 0.1 0.0 5.6 1.1 1.9 0.0 0.2 0.1 39.8 37.8 1.7 0.1 0.3 0.1 0.1 0.7 0.0 0.5 0.0 0.3 0.7 3.0 0.0 1.2 0.0 0.0 2.3 83.5 0.1 0.1 0.5 8.0 0.8 0.1 0.1 0.8 0.0 0.0 0.3 2.5 0.3 0.3 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 8.1 0.1 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 9.9 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 1.8 0.0 0.2 0.0 0.1 0.7 1.2 0.0 1.1 0.0 0.1 0.0 0.1 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.1 0.7 0.2 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.1 0.2 0.2 0.1 0.3 0.1 0.3 0.1 0.1 0.3 0.2 9.6 0.5 0.7 18.0 13.4 23.4 1.3 12.0 3.3 13.1 2.0 1.5 140.2 6.1 20.2 0.0 2.7 4.7 672.6 33.2 1.8 4.8 8.2 1.1 0.6 19.2 0.8 0.1 0.7 4.1 0.9 61.7 10.5 4.5 1.9 0.4 52.6 0.6 1.7 0.1 283.9 6.1 1.6 2.3 6.3 0.6 3.1 7.2 0.0 0.1 0.2 1.0 0.0 0.1 11.1 724.4 0.7 4.5 28.1 2014.8 348.9 4.5 1.2 0.0 0.5 0.9 21.2 25.7 17.1 20.9 1.4 5.2 0.4 272.4 65.7 ANGPTL3 ANGPT5 ENSG00000132855 "Angiopoietin like 3" Q9Y5C1 1 62597520-62606313 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Lipid metabolism" Heparin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 675.7" "Group enriched" "Detected in some" 12 "Hepatocytes: 567.6;Proximal tubular cells: 272.5" "Cancer enriched" "Detected in some" 39 "liver cancer: 94.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA038097 Approved "Secreted to blood" NA NA 225000000 120000000 "Cluster 85: Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA038097: AB_10675628" "unprognostic (2.29e-1)" "unprognostic (8.01e-2)" "unprognostic (2.51e-1)" "unprognostic (4.06e-2)" "unprognostic (2.70e-1)" "unprognostic (1.25e-2)" "unprognostic (4.06e-2)" "unprognostic (1.56e-2)" "unprognostic (8.11e-3)" "unprognostic (6.85e-3)" "unprognostic (2.89e-2)" "unprognostic (1.20e-2)" "unprognostic (1.09e-2)" "unprognostic (3.08e-2)" "unprognostic (1.09e-2)" "unprognostic (5.38e-2)" "unprognostic (7.62e-2)" 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 53.0 675.7 0.0 0.0 0.2 0.2 0.1 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 4.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.1 0.1 0.1 0.2 0.2 0.1 0.2 0.2 0.4 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.3 11.5 0.0 5.5 0.0 0.0 0.0 0.0 33.2 0.0 0.0 0.1 0.1 0.7 0.0 16.0 0.1 0.2 0.1 0.0 2.6 0.3 0.0 0.0 9.7 567.6 0.1 0.0 0.1 0.0 0.0 16.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 272.5 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.9 0.1 0.0 0.0 ANKS4B "FLJ38819, HARP" ENSG00000175311 "Ankyrin repeat and sterile alpha motif domain containing 4B" Q8N8V4 16 21233699-21253850 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 12.3;kidney: 5.9;liver: 13.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 63.4;Enteroendocrine cells: 25.1;Hepatocytes: 28.0;Intestinal goblet cells: 40.0;Paneth cells: 38.2;Proximal enterocytes: 113.0;Proximal tubular cells: 37.5;Undifferentiated cells: 24.7" "Group enriched" "Detected in many" 8 "colorectal cancer: 12.2;liver cancer: 5.1;pancreatic cancer: 3.2;renal cancer: 3.3;stomach cancer: 5.0" "Region enriched" "Detected in single" 8 "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.3;HDLM-2: 3.4;Hep G2: 8.2;OE19: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA043523, HPA061125" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Cytosol" "HPA043523: AB_10966687, HPA061125: " "unprognostic (1.35e-1)" "unprognostic (4.96e-2)" "unprognostic (2.73e-2)" "unprognostic (3.32e-2)" "unprognostic (8.42e-3)" "unprognostic (8.61e-2)" "unprognostic (2.36e-1)" "unprognostic (9.48e-2)" "unprognostic (2.04e-1)" "unprognostic (4.08e-1)" "unprognostic (1.08e-1)" "unprognostic (9.75e-4)" "unprognostic (5.15e-3)" "unprognostic (1.88e-1)" "unprognostic (4.77e-2)" "unprognostic (4.34e-3)" 0.0 0.0 0.1 0.6 0.2 0.1 0.0 2.1 0.2 0.0 0.0 8.9 9.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 5.9 13.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 7.1 0.2 0.0 0.0 0.7 0.1 12.3 0.2 0.0 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.1 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 2.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.6 0.0 0.7 0.0 0.0 0.4 0.0 0.1 0.8 2.8 0.6 1.8 0.0 0.0 0.0 63.4 0.0 0.2 0.8 0.3 0.1 0.3 25.1 0.0 1.3 1.7 0.0 0.2 0.0 0.1 1.3 0.0 0.4 28.0 0.0 0.0 0.2 40.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.5 0.0 0.0 0.1 1.3 38.2 0.0 0.0 0.5 113.0 37.5 0.0 0.3 0.0 1.5 0.3 0.2 0.0 0.0 0.0 0.1 0.6 0.0 24.7 0.4 ANPEP "CD13, gp150, LAP1, p150, PEPN" ENSG00000166825 "Alanyl aminopeptidase, membrane" P15144 15 89784895-89815401 "CD markers, Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Aminopeptidase, Developmental protein, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 2384.1;pancreas: 675.0" "Cell type enriched" "Detected in many" 14 "Proximal enterocytes: 6315.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 5 "cerebral cortex: 9.2;thalamus: 17.4" "Immune cell enriched" "Detected in many" 4 "neutrophil: 227.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 227.1" "Cell line enhanced" "Detected in many" "ASC diff: 613.7;ASC TERT1: 764.2;BJ: 738.4;BJ hTERT+: 1135.6;fHDF/TERT166: 703.8;HMC-1: 660.3;HSkMC: 670.0;HUVEC TERT2: 874.8;TIME: 815.1;U-2197: 891.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "spinal cord: 14.8" "CAB002417, HPA004625" Enhanced Supported "Plasma membrane" NA NA 1200000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "CAB002417: AB_563491, HPA004625: AB_2667199" "unprognostic (6.31e-2)" "unprognostic (7.94e-3)" "unprognostic (6.91e-2)" "unprognostic (2.16e-1)" "unprognostic (2.50e-1)" "unprognostic (1.13e-1)" "unprognostic (2.23e-2)" "unprognostic (1.89e-1)" "unprognostic (2.50e-1)" "unprognostic (7.73e-2)" "unprognostic (5.28e-3)" "unprognostic (3.96e-1)" "unprognostic (4.04e-3)" "unprognostic (3.20e-2)" "unprognostic (2.01e-2)" "unprognostic (4.61e-3)" "unprognostic (1.99e-2)" 55.4 7.0 1.6 36.6 1.6 103.4 55.9 1.3 9.2 41.4 3.4 266.8 2384.1 3.6 1.7 4.8 8.0 120.3 6.9 1.3 1.5 249.7 271.8 34.3 12.8 1.5 2.1 1.9 675.0 0.8 1.9 33.1 2.5 94.0 59.9 0.0 42.1 5.5 2.5 32.5 1970.6 29.7 1.3 25.9 8.0 2.0 17.4 7.1 8.2 3.8 4.7 16.8 15.0 1.2 0.1 45.6 0.0 0.5 613.7 764.2 6.2 738.4 1135.6 95.3 81.6 5.8 0.4 0.2 8.4 703.8 0.0 0.6 5.6 0.2 38.6 0.1 0.1 137.3 4.6 122.8 352.0 11.4 660.3 670.0 1.4 302.3 0.3 4.4 874.8 0.0 3.8 0.8 37.8 0.1 0.6 355.4 1.9 0.0 49.9 0.3 0.1 9.5 449.2 0.0 1.2 7.2 0.1 1.3 0.1 1.8 0.5 72.1 815.1 385.3 0.6 891.4 0.1 0.4 0.1 0.1 0.9 0.9 20.5 22.2 56.3 41.1 0.1 27.4 0.0 0.2 0.0 0.0 26.2 0.2 0.0 0.0 227.1 0.0 49.7 0.7 0.0 25.7 1.6 1.6 1.3 9.2 1.3 1.5 1.5 2.1 2.5 1.3 17.4 1.2 2.4 0.0 3.0 0.0 5.2 9.9 2.8 1.4 0.6 0.0 35.7 12.8 1.2 391.7 19.7 20.2 0.0 13.0 0.7 429.8 43.0 15.4 0.2 0.5 10.1 8.4 3.0 6.6 0.3 386.2 16.3 31.0 0.0 0.4 24.1 0.3 79.2 192.4 37.5 0.0 0.3 199.6 2.0 54.1 63.2 0.2 2.8 71.9 3.6 0.0 38.3 0.0 0.0 0.0 0.1 75.5 316.9 1.5 2.1 20.9 6315.2 435.0 3.3 0.0 26.3 0.8 8.1 0.3 0.5 0.2 5.8 6.4 3.7 187.8 290.9 1.4 AOC3 "HPAO, VAP-1, VAP1" ENSG00000131471 "Amine oxidase copper containing 3" Q16853 17 42851184-42858130 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 422.8" "Group enriched" "Detected in many" 4 "Adipocytes: 58.2;Peritubular cells: 74.9;Sertoli cells: 118.3;Smooth muscle cells: 93.0;Theca cells: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 17 "ASC diff: 307.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA000980, CAB025797" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted - unknown location" NA NA 240000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "Golgi apparatus" "CAB025797: , HPA000980: AB_1078170" "unprognostic (2.20e-1)" "unprognostic (4.49e-2)" "prognostic unfavorable (3.68e-4)" "unprognostic (2.97e-2)" "unprognostic (1.17e-1)" "unprognostic (2.64e-1)" "unprognostic (2.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.48e-1)" "unprognostic (4.00e-2)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (1.79e-5)" "unprognostic (5.61e-2)" "unprognostic (1.67e-1)" "unprognostic (8.39e-2)" "prognostic unfavorable (6.98e-4)" 422.8 48.4 2.6 31.9 3.2 1.4 169.2 2.5 4.2 52.8 2.7 210.8 17.3 95.1 33.5 88.0 84.8 50.7 50.2 2.9 2.5 24.1 19.1 218.6 12.4 2.5 2.5 26.5 12.0 8.4 5.4 28.0 2.6 59.1 41.0 1.7 14.7 103.6 17.8 24.6 57.6 144.8 2.3 21.4 66.6 12.8 2.4 5.9 28.2 22.9 3.9 142.1 50.9 2.5 0.1 1.5 0.2 1.0 307.5 0.3 5.0 0.3 0.1 0.2 0.8 0.9 0.0 0.7 0.7 0.1 0.2 0.5 0.8 0.2 0.8 1.5 5.7 0.4 0.5 18.4 0.8 0.3 1.0 3.3 1.0 0.3 0.8 0.0 0.2 2.2 0.3 1.7 0.6 0.2 0.2 1.4 0.7 0.1 0.4 0.7 0.8 3.0 0.1 2.2 0.3 0.4 0.0 0.2 2.0 2.2 0.1 0.1 0.0 0.3 2.7 1.2 0.4 4.8 5.9 0.6 0.4 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.6 3.2 2.5 4.2 2.9 2.5 2.5 2.5 2.6 2.3 2.4 2.5 58.2 3.2 6.0 0.0 0.5 2.9 0.1 0.0 2.2 0.0 1.1 2.2 9.5 0.0 1.9 0.0 0.0 0.1 0.4 0.1 0.0 0.2 4.5 0.8 2.3 12.3 0.0 0.0 0.4 0.2 0.1 11.3 0.0 1.4 1.3 2.1 20.7 0.2 1.4 0.0 0.3 0.1 0.0 1.4 2.7 2.6 3.4 0.9 3.6 3.7 0.0 0.2 0.0 0.0 0.1 0.2 0.0 74.9 0.0 0.4 0.1 1.4 1.0 0.4 118.3 2.6 93.0 1.1 1.3 0.7 1.8 0.3 0.6 74.6 0.1 0.3 AOX1 "AO, AOH1" ENSG00000138356 "Aldehyde oxidase 1" Q06278 2 200586014-200677064 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adrenal gland: 300.5;liver: 891.0" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 749.1" "Cancer enriched" "Detected in many" 9 "liver cancer: 122.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 377.3;ASC TERT1: 191.5;HSkMC: 78.2;hTERT-HME1: 81.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA040199, HPA040215" Enhanced NA NA 3300000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "HPA040199: AB_10795273, HPA040215: AB_10795360" "unprognostic (4.39e-2)" "unprognostic (1.03e-3)" "unprognostic (1.96e-1)" "unprognostic (3.15e-2)" "unprognostic (1.17e-4)" "unprognostic (1.92e-2)" "unprognostic (2.34e-2)" "unprognostic (3.54e-1)" "unprognostic (1.15e-1)" "unprognostic (4.93e-2)" "unprognostic (5.48e-2)" "unprognostic (2.00e-2)" "prognostic favorable (6.05e-5)" "unprognostic (1.33e-2)" "unprognostic (8.16e-3)" "unprognostic (3.38e-2)" "unprognostic (4.99e-3)" 87.6 300.5 0.6 3.2 2.9 0.5 50.2 0.1 2.4 17.9 3.6 12.0 0.8 10.8 12.3 8.2 48.2 9.9 14.9 1.1 1.5 103.2 891.0 19.5 4.7 1.3 1.0 48.0 85.0 1.3 2.8 1.7 1.2 22.3 4.5 0.5 15.3 28.3 12.9 20.1 12.7 7.1 0.5 4.1 14.3 19.4 4.0 2.0 17.7 11.0 1.5 38.6 17.7 3.6 0.6 0.2 0.0 0.0 377.3 191.5 0.2 6.6 12.2 5.4 9.7 0.0 0.1 0.1 0.5 8.4 2.3 0.2 0.1 18.6 22.0 0.2 0.6 0.0 4.6 20.7 25.4 0.9 0.0 78.2 4.6 26.1 81.2 5.4 0.2 0.2 0.2 0.1 18.3 0.5 0.0 0.1 8.0 0.1 5.2 0.0 0.5 0.1 0.2 0.2 0.4 0.3 4.8 0.0 0.3 0.4 0.1 0.2 31.9 13.8 11.2 0.2 2.5 0.2 0.1 2.6 10.7 0.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.9 0.1 2.4 1.1 1.5 1.3 1.0 1.2 0.5 4.0 3.6 1.0 3.2 1.1 0.7 3.6 1.8 0.5 1.2 1.2 0.1 0.2 0.3 0.9 17.2 0.1 3.7 0.0 0.1 0.0 0.1 11.7 0.7 0.8 0.4 3.0 2.6 3.0 37.5 0.9 26.2 0.2 22.9 0.0 8.2 0.0 0.1 15.4 749.1 0.4 0.0 2.5 0.1 2.0 19.8 3.6 4.4 74.0 1.7 3.6 1.0 0.0 0.6 0.0 5.0 6.9 11.5 0.0 82.0 0.0 7.5 0.1 162.2 0.1 0.1 0.0 5.3 3.0 0.8 1.3 0.1 1.6 0.0 2.0 2.3 0.1 0.4 APLP1 APLP ENSG00000105290 "Amyloid beta precursor like protein 1" P51693 19 35867899-35879792 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion, Endocytosis" Heparin-binding Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 1201.6" "Group enriched" "Detected in many" 4 "Bipolar cells: 147.1;Horizontal cells: 161.5;Oligodendrocytes: 461.3" "Cancer enhanced" "Detected in many" "glioma: 63.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 81.6;AN3-CA: 162.9;HMC-1: 76.0;SCLC-21H: 87.2;SH-SY5Y: 89.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028970, HPA028971" Enhanced Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA 6400000 "Cluster 11: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Plasma membrane" Nucleoplasm "HPA028970: AB_2672847, HPA028971: AB_10601334" "unprognostic (1.33e-2)" "unprognostic (2.07e-1)" "unprognostic (9.36e-3)" "prognostic unfavorable (3.87e-4)" "unprognostic (7.32e-3)" "unprognostic (1.26e-2)" "unprognostic (1.04e-3)" "unprognostic (2.24e-2)" "unprognostic (4.98e-2)" "unprognostic (6.16e-2)" "unprognostic (2.35e-2)" "unprognostic (1.13e-1)" "unprognostic (2.57e-11)" "unprognostic (1.38e-3)" "unprognostic (7.12e-2)" "unprognostic (5.43e-2)" "prognostic unfavorable (2.65e-5)" 3.0 31.5 417.1 3.1 718.0 0.4 1.4 680.9 552.4 3.1 218.6 4.4 1.8 3.1 1.3 1.5 2.7 5.5 10.8 438.3 465.8 4.9 0.6 1.9 1.4 783.2 627.4 1.4 75.0 22.3 151.4 0.9 710.7 2.1 2.2 56.3 1.8 1.9 0.5 1.1 2.1 3.2 605.9 0.5 28.1 13.1 598.3 0.8 1.5 0.5 1.5 1.2 2.1 1201.6 4.4 40.0 81.6 162.9 7.1 3.2 10.4 5.6 3.5 7.8 1.1 7.3 6.3 0.8 66.5 21.0 27.7 2.2 26.1 2.6 5.2 48.9 3.7 0.3 10.6 5.2 2.0 0.2 76.0 3.6 1.8 3.2 0.1 28.8 3.1 6.1 2.7 1.2 25.0 8.3 0.2 0.3 3.9 16.5 16.5 7.2 0.4 1.1 1.4 1.1 87.2 89.3 23.1 3.8 0.8 23.9 20.8 4.3 1.3 61.3 28.8 32.9 4.3 2.4 1.6 0.3 42.3 1.1 33.3 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.6 0.0 0.0 0.0 0.0 417.1 718.0 680.9 552.4 438.3 465.8 783.2 627.4 710.7 605.9 598.3 1201.6 2.5 6.4 0.0 12.4 0.6 1.3 2.6 0.7 1.2 147.1 0.4 1.1 6.2 1.5 0.2 0.0 12.5 0.3 0.3 0.4 0.0 2.0 27.6 1.3 1.2 2.8 34.9 0.0 55.5 4.2 6.4 2.8 10.2 3.2 0.0 0.1 0.7 0.4 0.4 161.5 46.8 1.1 2.0 0.3 1.6 15.8 1.2 1.1 5.4 12.2 0.0 14.6 0.0 19.1 461.3 3.1 0.1 0.0 0.4 1.9 0.0 0.1 0.2 38.6 0.0 1.9 1.8 14.5 28.7 0.1 0.6 0.4 0.5 0.1 0.2 1.3 APOE AD2 ENSG00000130203 "Apolipoprotein E" P02649 19 44905791-44909393 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Hyperlipidemia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adrenal gland: 3453.9;liver: 6592.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 9363.4;Hofbauer cells: 6072.6;Muller glia cells: 9454.8;Peritubular cells: 4958.2;Proximal tubular cells: 8155.9;Theca cells: 7201.0" "Cancer enhanced" "Detected in all" "liver cancer: 3183.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1867.0;CACO-2: 466.1;Hep G2: 935.3;HSkMC: 1374.2;SK-MEL-30: 1956.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008363, HPA065539, HPA068768, CAB069921" Enhanced Approved Vesicles "Secreted to blood" NA NA 51800000000 29000000000 "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB008363: AB_590560, CAB069921: AB_920623, HPA065539: AB_2685509, HPA068768: AB_2686029" "unprognostic (8.98e-2)" "unprognostic (2.32e-2)" "unprognostic (2.49e-2)" "unprognostic (5.28e-2)" "unprognostic (3.77e-2)" "unprognostic (7.25e-2)" "unprognostic (5.22e-3)" "unprognostic (6.13e-2)" "unprognostic (5.06e-2)" "unprognostic (4.13e-1)" "unprognostic (5.78e-2)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (7.76e-2)" "unprognostic (1.64e-1)" "unprognostic (1.12e-3)" "unprognostic (4.13e-2)" 522.1 3453.9 813.4 92.8 1164.2 66.5 325.1 775.0 943.2 271.2 329.2 130.9 40.3 81.5 20.0 37.2 72.2 100.2 176.3 606.1 841.6 1066.0 6592.5 258.8 352.2 1016.0 1037.0 508.2 41.9 34.5 110.9 102.2 1106.9 45.4 22.9 87.6 80.5 10.8 31.1 381.2 165.9 12.6 823.2 620.3 83.3 140.5 962.6 57.8 146.4 10.4 46.1 93.4 135.5 964.4 3.2 5.2 9.5 2.6 1867.0 76.3 69.4 1.5 4.3 8.4 1.4 466.1 2.8 2.0 9.9 0.3 9.1 6.4 12.6 2.1 0.7 1.7 4.0 3.3 1.7 935.3 192.4 6.8 2.3 1374.2 2.5 14.8 1.3 15.6 1.0 0.7 124.9 2.8 1.2 3.3 1.9 2.5 243.2 3.0 1.3 2.6 8.0 1.8 2.8 0.9 5.6 2.4 4.5 1.4 1956.0 131.6 165.3 52.8 3.3 13.2 3.1 1.4 1.6 5.9 8.6 3.8 5.9 4.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 813.4 1164.2 775.0 943.2 606.1 841.6 1016.0 1037.0 1106.9 823.2 962.6 964.4 136.7 0.0 8.2 444.0 66.1 935.2 12.3 18.3 67.7 81.7 86.7 565.8 2.2 450.4 5.2 228.1 41.7 46.3 6.0 2.2 682.9 1.8 73.6 33.8 936.6 140.2 0.0 331.6 1.1 0.7 43.8 860.7 3.6 22.9 174.4 103.6 208.9 9363.4 6072.6 38.7 2.1 0.6 4.1 718.0 292.6 355.3 2629.4 940.6 2481.3 60.9 70.3 9454.8 0.0 12.1 2.2 0.6 0.3 4958.2 7.2 15.0 0.2 8155.9 1.0 311.4 223.5 2958.4 345.5 14.8 12.8 15.1 1684.9 74.3 60.6 7201.0 1.7 4.7 APOM "G3a, NG20" ENSG00000204444 "Apolipoprotein M" O95445 6 31652416-31658210 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 390.7" "Group enriched" "Detected in many" 8 "Hepatocytes: 665.9;Proximal tubular cells: 681.1" "Cancer enriched" "Detected in all" 13 "liver cancer: 185.9" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "basophil: 3.0" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 12 "Hep G2: 38.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034086, HPA051006" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 7400000000 8200000000 "Cluster 34: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "CAB034086: AB_1119033, HPA051006: AB_2681307" "unprognostic (2.76e-3)" "unprognostic (1.69e-2)" "unprognostic (8.66e-2)" "unprognostic (2.61e-2)" "unprognostic (1.12e-1)" "unprognostic (5.28e-2)" "unprognostic (3.78e-1)" "unprognostic (1.97e-2)" "unprognostic (1.80e-1)" "unprognostic (6.04e-3)" "unprognostic (2.27e-2)" "unprognostic (1.48e-1)" "unprognostic (7.28e-2)" "unprognostic (5.71e-2)" "unprognostic (1.96e-1)" "unprognostic (1.30e-1)" "unprognostic (3.20e-2)" 4.9 5.3 0.6 0.1 0.6 2.5 5.2 1.0 0.9 3.7 0.5 3.8 0.6 3.9 1.0 4.1 4.1 0.5 3.5 0.6 0.7 93.7 390.7 2.6 0.6 0.7 0.7 6.2 6.0 0.7 4.7 0.1 0.7 3.8 0.4 0.4 3.5 0.5 7.2 6.4 9.0 0.4 0.7 4.1 5.3 16.0 0.6 1.2 5.5 0.6 1.1 3.3 3.3 0.8 0.5 0.3 0.6 0.7 0.6 0.8 0.0 0.4 1.1 0.4 0.9 3.2 1.0 1.4 0.2 1.1 0.2 0.6 0.4 0.6 0.8 0.8 0.7 0.8 0.3 38.2 1.3 1.7 0.1 1.2 0.4 0.3 1.0 0.5 0.3 0.9 1.2 0.4 1.1 1.1 1.1 0.9 0.5 0.6 0.2 0.8 0.4 1.5 1.1 0.6 0.5 0.2 0.4 0.0 0.5 0.2 1.5 1.2 0.4 0.2 0.1 0.3 0.3 1.1 1.2 1.5 0.2 1.8 0.1 3.0 0.6 0.6 0.3 0.3 0.5 1.1 0.4 0.3 0.5 0.5 0.5 0.6 0.4 0.3 0.7 0.3 0.7 0.3 0.6 0.6 1.0 0.9 0.6 0.7 0.7 0.7 0.7 0.7 0.6 0.8 1.5 0.0 7.4 2.3 9.0 6.4 6.7 6.7 9.1 1.5 6.6 12.4 1.6 12.8 3.0 14.7 4.2 2.0 1.6 4.1 76.3 4.3 60.2 5.2 3.1 2.0 4.2 11.4 0.3 6.9 0.9 4.3 5.1 1.6 5.1 1.8 8.9 665.9 5.4 0.0 0.4 4.9 2.0 14.5 4.2 38.4 9.3 6.1 5.4 0.0 2.5 14.6 1.0 0.5 1.3 6.4 4.9 6.4 7.4 4.2 81.4 681.1 4.6 2.5 0.0 6.2 3.1 33.1 6.6 5.3 6.5 1.2 5.6 4.6 6.5 6.1 AQP7 "AQP7L, AQP9, AQPap" ENSG00000165269 "Aquaporin 7" O14520 9 33383179-33402682 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 252.7;breast: 104.9;heart muscle: 108.5" "Cell type enhanced" "Detected in many" "Adipocytes: 129.7;Cardiomyocytes: 86.0;Early spermatids: 128.5;Proximal enterocytes: 160.7;Proximal tubular cells: 61.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 43 "ASC diff: 196.0" "Not detected" "Not detected" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "unprognostic (3.25e-2)" "unprognostic (3.81e-3)" "unprognostic (1.25e-5)" "unprognostic (7.22e-3)" "unprognostic (1.50e-1)" "unprognostic (3.32e-1)" "unprognostic (4.67e-2)" "unprognostic (3.06e-2)" "unprognostic (9.99e-2)" "unprognostic (4.65e-2)" "unprognostic (8.56e-4)" "unprognostic (1.21e-1)" "prognostic favorable (9.21e-8)" "unprognostic (2.42e-1)" "unprognostic (1.28e-1)" "unprognostic (1.61e-1)" "unprognostic (2.12e-3)" 252.7 5.0 0.9 1.9 1.3 0.0 104.9 4.4 1.4 1.3 0.0 6.6 17.9 1.7 2.9 2.8 5.9 3.4 108.5 0.8 0.7 24.2 23.5 1.2 0.7 4.8 0.7 1.8 3.8 18.3 0.3 0.5 5.8 1.2 4.0 0.3 6.4 2.5 33.8 6.2 26.8 2.5 0.3 1.3 2.8 30.4 1.0 1.0 4.8 51.9 0.2 4.7 2.2 1.2 0.1 1.9 0.2 0.1 196.0 4.5 0.2 0.0 0.0 0.0 0.0 2.2 0.1 0.2 0.1 0.1 0.1 0.3 0.1 1.1 0.0 0.1 0.0 0.1 0.4 2.2 0.2 0.0 0.2 3.1 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 0.1 0.2 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 4.5 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.9 1.3 4.4 1.4 0.8 0.7 4.8 0.7 5.8 0.3 1.0 1.2 129.7 6.4 7.3 0.3 0.2 1.5 0.3 0.3 0.0 0.0 0.8 1.5 86.0 14.3 0.9 35.0 0.0 0.0 0.6 30.7 5.9 1.9 128.5 9.1 0.2 11.2 0.0 0.0 0.1 0.2 0.3 4.1 0.0 0.7 0.0 0.2 2.9 20.1 0.1 0.0 0.1 9.2 0.0 0.3 0.3 21.4 2.1 1.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.2 22.5 1.9 0.1 0.5 160.7 61.4 7.7 0.0 6.6 1.7 9.6 4.1 0.7 1.3 2.6 0.0 0.3 0.9 4.3 2.1 ARHGAP28 "FLJ10312, KIAA1314" ENSG00000088756 "Rho GTPase activating protein 28" Q9P2N2 18 6729716-6915716 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "placenta: 25.9;testis: 77.5" "Group enriched" "Detected in many" 14 "Early spermatids: 536.8;Late spermatids: 488.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 4 "neutrophil: 3.0" "Lineage enriched" "Detected in single" 11 "granulocytes: 3.0" "Cell line enhanced" "Detected in many" "AF22: 30.4;CACO-2: 32.8;SuSa: 22.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA030413, HPA030414, HPA030415" Enhanced Supported "Cell Junctions" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 83: Testis - Spermatogenesis" "Cluster 12: NES - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Cell Junctions" "HPA030413: AB_10601455, HPA030414: AB_10670042, HPA030415: AB_10669598" "unprognostic (8.33e-2)" "unprognostic (8.79e-3)" "unprognostic (3.15e-3)" "unprognostic (6.94e-5)" "unprognostic (1.49e-1)" "unprognostic (2.92e-2)" "unprognostic (1.11e-3)" "unprognostic (1.10e-1)" "unprognostic (7.56e-3)" "unprognostic (9.52e-4)" "unprognostic (1.43e-2)" "unprognostic (3.12e-1)" "unprognostic (4.53e-3)" "unprognostic (3.59e-3)" "unprognostic (6.00e-2)" "unprognostic (3.61e-2)" "unprognostic (2.76e-2)" 4.7 1.9 1.1 1.7 1.2 0.8 2.7 1.7 1.6 8.6 0.8 1.9 1.7 2.9 8.7 1.9 3.1 6.6 2.0 1.5 1.6 8.4 0.9 4.6 1.7 0.4 0.2 10.4 3.8 3.0 0.8 25.9 0.5 3.9 2.3 1.4 0.8 2.2 4.9 2.1 1.8 1.4 0.1 12.6 2.1 77.5 1.1 3.8 2.9 1.6 0.9 5.4 3.0 0.8 0.2 0.2 30.4 3.1 6.3 10.5 4.9 2.2 5.1 2.5 5.3 32.8 0.2 0.2 1.0 0.4 1.7 1.4 0.1 0.8 3.7 1.0 1.8 0.1 2.9 0.2 1.1 0.1 0.1 12.6 0.6 2.7 0.2 0.3 7.8 0.5 0.8 2.5 4.1 0.5 0.5 0.3 9.6 0.4 1.4 0.1 2.7 0.2 0.0 2.9 2.9 11.9 0.1 2.8 0.5 22.6 0.2 0.1 1.3 0.5 13.1 10.1 0.4 0.2 0.1 0.1 5.0 0.3 1.1 0.7 0.2 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.1 3.0 0.1 0.0 0.2 0.0 0.0 1.1 1.2 1.7 1.6 1.5 1.6 0.4 0.2 0.5 0.1 1.1 0.8 8.3 0.0 1.9 6.2 0.1 1.9 1.3 0.2 0.0 1.5 0.9 0.5 1.8 0.0 0.7 1.8 20.9 14.9 0.0 0.0 0.0 1.1 536.8 0.5 14.6 7.9 0.0 0.0 7.1 2.7 2.7 16.1 0.0 0.4 0.0 25.8 4.2 0.2 2.1 0.0 34.4 0.1 0.0 0.3 0.4 488.0 18.3 0.5 0.0 12.2 0.0 0.2 0.0 24.6 3.6 0.7 0.0 14.3 0.1 4.7 0.0 3.8 0.0 0.8 0.0 11.0 5.4 14.3 3.7 0.8 1.4 6.6 0.3 23.7 0.0 1.3 ARMH4 "C14orf37, UT2" ENSG00000139971 "Armadillo like helical domain containing 4" Q86TY3 14 57999735-58298139 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.8;kidney: 8.3" "Cell type enhanced" "Detected in some" "Adipocytes: 15.8;Collecting duct cells: 12.9;Endometrial ciliated cells: 10.2;Endometrial stromal cells: 7.7;Granulosa cells: 26.0;Theca cells: 44.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 9.7;AN3-CA: 6.1;fHDF/TERT166: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001580, HPA001789" Enhanced Approved "Plasma membrane" NA NA 1800000 "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Plasma membrane" "HPA001580: AB_2666366, HPA001789: AB_1078328" "unprognostic (2.56e-2)" "unprognostic (2.04e-2)" "unprognostic (1.20e-3)" "unprognostic (8.56e-2)" "unprognostic (1.15e-1)" "unprognostic (6.97e-3)" "unprognostic (1.94e-1)" "unprognostic (7.84e-3)" "unprognostic (2.66e-1)" "unprognostic (2.32e-1)" "unprognostic (2.42e-1)" "unprognostic (1.01e-1)" "unprognostic (3.87e-8)" "unprognostic (5.22e-6)" "unprognostic (4.93e-2)" "unprognostic (8.74e-4)" "unprognostic (3.01e-4)" 1.2 2.5 2.3 0.6 3.6 0.7 0.8 8.5 3.5 1.8 0.0 0.7 0.5 3.0 1.8 0.8 2.1 1.8 3.1 2.6 2.1 8.3 0.8 0.7 0.4 11.5 5.1 4.3 1.0 3.6 1.3 0.4 12.8 1.6 1.0 1.2 0.7 1.4 0.2 1.0 0.7 2.3 1.0 0.5 1.4 2.2 1.6 0.2 1.5 1.9 0.3 1.2 0.9 0.7 0.0 0.0 9.7 6.1 4.7 1.7 0.0 1.9 1.5 0.3 0.3 0.5 0.1 0.0 0.6 10.8 1.2 0.0 2.9 0.0 0.4 0.1 1.0 0.0 0.0 0.5 0.2 0.0 4.8 1.8 0.0 0.2 0.2 2.7 0.5 0.8 0.1 0.3 1.2 0.3 0.0 0.0 4.5 0.0 2.0 1.4 0.3 2.5 3.9 0.3 1.1 0.0 0.1 0.0 0.3 2.7 0.2 0.2 0.1 1.3 3.5 0.5 2.6 0.3 0.2 0.0 3.0 0.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.6 8.5 3.5 2.6 2.1 11.5 5.1 12.8 1.0 1.6 0.7 15.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 12.9 0.0 0.2 0.7 0.0 0.0 2.1 0.0 10.2 7.7 2.3 0.0 0.0 0.0 1.3 0.4 3.0 0.0 2.4 0.0 26.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.3 0.3 44.5 0.0 0.0 ARSF ENSG00000062096 "Arylsulfatase F" P54793 X 3041471-3112727 "Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9;kidney: 7.6;skin 1: 5.6" "Cell type enhanced" "Detected in some" "Astrocytes: 9.4;Distal tubular cells: 1.9;Inhibitory neurons: 4.6;Oligodendrocyte precursor cells: 2.5;Proximal tubular cells: 10.5" "Cancer enhanced" "Detected in some" "glioma: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA000549 Uncertain Cytosol "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA000549: AB_1845055" "unprognostic (2.19e-2)" "unprognostic (8.88e-2)" "unprognostic (2.87e-1)" "unprognostic (5.41e-3)" "unprognostic (3.83e-1)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (9.72e-2)" "unprognostic (4.70e-1)" "unprognostic (6.33e-2)" "unprognostic (1.29e-1)" "unprognostic (3.05e-2)" "unprognostic (3.59e-1)" "unprognostic (1.23e-1)" "unprognostic (9.76e-2)" "unprognostic (1.48e-1)" 0.0 3.0 2.6 0.0 3.6 0.1 0.2 3.0 2.7 0.4 1.5 0.0 0.0 0.0 1.6 2.6 0.0 0.0 0.0 3.2 2.1 7.6 1.6 0.0 0.0 4.9 2.9 0.0 0.6 0.3 0.0 0.0 3.1 0.1 0.0 0.1 0.2 0.0 0.1 5.6 0.0 0.0 2.8 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.5 0.2 1.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.6 3.6 3.0 2.7 3.2 2.1 4.9 2.9 3.1 2.8 3.0 2.1 0.0 0.0 0.0 9.4 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 ASB15 FLJ43370 ENSG00000146809 "Ankyrin repeat and SOCS box containing 15" Q8WXK1 7 123567010-123639481 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 27.3;skeletal muscle: 119.3;tongue: 84.1" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 54.2;Early spermatids: 35.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (1.19e-1)" "unprognostic (7.45e-2)" "unprognostic (1.37e-1)" "unprognostic (5.98e-1)" "unprognostic (6.09e-6)" "unprognostic (7.31e-2)" "unprognostic (6.39e-2)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 27.3 0.1 0.1 7.4 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.5 0.0 119.3 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 84.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.5 0.0 0.2 0.4 0.0 1.7 0.3 0.3 54.2 0.0 0.2 0.0 0.0 0.2 0.2 0.3 1.9 0.2 35.0 0.8 0.4 0.4 0.0 0.0 0.4 0.4 1.4 0.9 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.4 5.6 0.6 0.0 3.6 0.0 0.0 0.3 0.0 0.5 0.1 0.7 0.0 0.0 0.0 0.7 0.1 10.4 0.1 0.1 0.0 6.9 0.8 1.2 0.4 0.0 0.1 1.1 0.2 0.3 0.2 0.3 ASPDH ENSG00000204653 "Aspartate dehydrogenase domain containing" A6ND91 19 50511600-50514690 "Enzymes, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.1;kidney: 39.0;liver: 132.4" "Group enriched" "Detected in some" 6 "Hepatocytes: 135.8;Proximal tubular cells: 487.2" "Cancer enriched" "Detected in some" 13 "liver cancer: 24.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 13.6;MOLT-4: 16.5;SH-SY5Y: 9.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042631, HPA042654" Approved Approved Nucleoplasm,Cytosol NA NA 200000 "Cluster 15: Liver - Metabolism" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Cytosol "HPA042631: AB_10794530, HPA042654: AB_10794383" "unprognostic (5.79e-2)" "unprognostic (9.47e-2)" "unprognostic (8.97e-3)" "unprognostic (6.13e-3)" "unprognostic (5.13e-1)" "unprognostic (3.64e-2)" "unprognostic (3.15e-3)" "unprognostic (3.32e-2)" "unprognostic (2.87e-2)" "unprognostic (2.09e-2)" "unprognostic (2.87e-3)" "unprognostic (6.70e-3)" "unprognostic (9.65e-3)" "unprognostic (3.36e-2)" "unprognostic (1.07e-1)" "unprognostic (5.31e-4)" "unprognostic (1.99e-3)" 0.5 2.5 18.1 0.9 20.9 0.5 0.0 23.7 40.1 0.0 7.3 0.2 6.6 0.2 0.0 0.3 0.0 1.7 0.3 19.8 17.3 39.0 132.4 0.2 0.9 17.0 17.5 0.0 0.8 0.0 19.6 0.0 16.8 0.3 0.0 5.4 1.6 0.0 0.3 1.1 2.5 0.0 13.4 0.6 0.3 0.2 22.9 2.4 0.9 0.0 0.0 0.1 0.1 21.9 0.1 2.2 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 13.6 0.0 0.7 3.8 0.0 1.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.4 1.7 0.0 1.6 16.5 0.1 0.0 0.6 0.2 0.4 0.3 1.1 0.0 0.2 1.7 9.2 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 3.6 0.8 1.8 0.2 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.1 20.9 23.7 40.1 19.8 17.3 17.0 17.5 16.8 13.4 22.9 21.9 0.0 0.0 0.0 3.3 2.0 0.0 0.0 0.0 0.0 29.8 0.0 0.0 0.4 1.5 0.0 9.2 4.2 0.0 0.0 0.1 45.0 0.0 0.7 0.0 0.0 0.1 7.1 10.7 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 135.8 0.0 0.0 4.4 0.1 0.0 1.9 0.0 2.5 0.0 3.4 0.0 2.8 0.0 0.7 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 8.8 487.2 0.0 4.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.1 0.0 0.1 0.0 ASS1 "ASS, CTLN1" ENSG00000130707 "Argininosuccinate synthase 1" P00966 9 130444961-130501274 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 1284.8;liver: 2037.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 398.7;Hepatocytes: 1062.0;Proximal enterocytes: 618.2;Proximal tubular cells: 1408.9;Urothelial cells: 413.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 15 "dendritic cells: 1.5" "Cell line enhanced" "Detected in many" "BJ hTERT+: 893.9;HaCaT: 850.4;hTCEpi: 817.8;RPMI-8226: 1444.5;THP-1: 1061.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020896, HPA020934" Enhanced Supported Nucleoplasm,Cytosol No No 6400000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA020896: AB_1845117, HPA020934: AB_1845118" "unprognostic (3.73e-2)" "unprognostic (1.77e-2)" "unprognostic (2.78e-1)" "prognostic unfavorable (8.14e-9)" "unprognostic (3.06e-1)" "unprognostic (1.05e-2)" "unprognostic (2.93e-2)" "unprognostic (3.71e-2)" "unprognostic (3.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.02e-2)" "unprognostic (4.24e-2)" "unprognostic (2.92e-3)" "unprognostic (1.41e-2)" "unprognostic (1.05e-1)" "unprognostic (3.14e-1)" "unprognostic (4.72e-3)" 215.0 146.8 29.6 51.3 29.7 0.2 168.2 25.0 31.0 67.0 61.7 157.2 124.5 111.3 124.8 51.1 166.3 110.2 66.5 31.5 38.3 1284.8 2037.7 52.9 7.5 40.2 42.2 57.2 68.4 11.4 45.0 50.6 51.7 56.2 167.9 6.9 119.4 132.6 74.4 131.3 194.8 61.2 28.4 20.0 53.2 35.9 38.4 7.8 92.3 71.4 15.6 288.7 66.6 25.3 124.5 11.9 13.7 23.1 88.4 223.1 43.6 146.2 893.9 28.2 85.5 52.5 34.0 0.4 95.9 300.2 8.2 850.4 59.9 5.2 19.5 21.7 27.1 0.3 18.3 137.3 305.4 18.3 1.6 148.2 817.8 45.4 81.2 0.3 1.1 384.0 5.3 530.6 28.8 619.8 7.2 262.7 19.2 635.9 26.7 1.7 15.4 1444.5 78.8 61.3 342.4 5.8 515.4 534.7 41.5 53.5 366.1 1061.5 0.4 11.3 68.3 2.3 13.0 88.1 91.5 32.1 219.0 137.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 29.6 29.7 25.0 31.0 31.5 38.3 40.2 42.2 51.7 28.4 38.4 25.3 72.1 25.6 28.6 2.6 21.3 70.5 55.7 179.8 53.5 0.1 23.7 17.3 5.4 138.7 104.4 47.8 0.0 178.5 0.4 398.7 133.1 116.5 1.2 4.7 30.5 68.0 12.0 93.7 2.2 110.5 8.9 21.5 20.4 6.2 5.7 55.5 65.7 1062.0 14.7 0.0 8.0 186.8 24.4 40.1 6.5 7.8 31.1 8.0 3.6 7.5 1.6 10.6 0.0 0.0 0.2 70.8 310.4 124.8 11.7 104.0 618.2 1408.9 32.7 0.4 0.0 18.7 13.4 1.4 2.6 23.5 17.5 144.1 11.5 62.0 165.6 413.2 ATOH7 "bHLHa13, Math5" ENSG00000179774 "Atonal bHLH transcription factor 7" Q8N100 10 68230595-68232113 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.0;liver: 3.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Excitatory neurons: 1.7;Hepatocytes: 1.1;Spermatogonia: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "SCLC-21H: 7.5" "Region enriched" "Detected in some" 9 "cerebellum: 28.7" "Low region specificity" "Detected in some" HPA027008 Uncertain NA NA "Cluster 15: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA027008: AB_10600783" "unprognostic (7.17e-2)" "unprognostic (2.81e-1)" "unprognostic (7.66e-2)" "unprognostic (1.86e-2)" "unprognostic (2.20e-3)" "unprognostic (7.40e-2)" "unprognostic (7.76e-2)" "unprognostic (6.16e-2)" "unprognostic (2.46e-1)" "unprognostic (9.28e-4)" "unprognostic (4.96e-3)" "unprognostic (1.17e-1)" "unprognostic (5.06e-4)" "unprognostic (1.72e-1)" "unprognostic (2.52e-2)" "unprognostic (1.36e-1)" "unprognostic (7.18e-2)" 0.1 0.2 1.4 0.0 1.5 0.0 0.1 3.0 2.0 0.1 0.7 0.2 0.2 0.2 0.1 0.0 0.1 0.0 0.0 2.0 1.0 1.2 3.0 0.0 0.0 0.8 0.8 0.1 0.4 0.0 0.2 0.0 0.8 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.3 0.0 0.8 0.0 0.3 0.2 0.8 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 7.5 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.5 3.0 2.0 2.0 1.0 0.8 0.8 0.8 0.8 0.8 1.2 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.2 0.3 0.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.9 0.1 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.4 0.0 0.3 0.0 1.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.3 0.5 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 ATP6V0D2 "ATP6D2, FLJ38708, VMA6" ENSG00000147614 "ATPase H+ transporting V0 subunit d2" Q8N8Y2 8 85987323-86154225 "Metabolic proteins, Predicted intracellular proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 60.5" "Cell type enriched" "Detected in some" 6 "Distal tubular cells: 209.4" "Cancer enriched" "Detected in many" 9 "renal cancer: 36.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "SK-MEL-30: 3.3;SuSa: 5.8;U-87 MG: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA055327, HPA058496" Enhanced Approved Vesicles NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 7: Kidney - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA055327: AB_2682784, HPA058496: " "unprognostic (3.79e-2)" "unprognostic (1.59e-1)" "unprognostic (1.78e-1)" "unprognostic (1.22e-1)" "unprognostic (8.50e-2)" "unprognostic (8.43e-3)" "unprognostic (5.36e-5)" "unprognostic (4.02e-2)" "unprognostic (1.16e-1)" "unprognostic (7.75e-3)" "unprognostic (2.32e-2)" "unprognostic (1.61e-1)" "prognostic favorable (2.20e-6)" "unprognostic (8.58e-2)" "unprognostic (1.77e-2)" "unprognostic (3.67e-1)" "unprognostic (1.97e-2)" 0.3 0.0 0.6 0.7 1.4 1.9 0.8 0.4 0.7 0.4 0.4 3.1 1.6 0.3 1.4 0.7 0.0 0.5 0.4 0.5 0.7 60.5 0.4 2.6 1.3 0.6 1.1 0.0 0.4 1.3 0.0 0.8 0.6 1.4 3.5 14.0 1.1 2.5 0.0 1.7 1.3 0.4 0.3 1.1 0.3 0.2 1.0 0.5 1.0 0.0 1.1 0.5 0.0 1.4 0.4 0.6 0.3 0.4 0.0 0.3 1.3 0.0 0.0 0.6 0.1 0.0 0.2 0.1 0.1 0.0 1.4 1.2 0.4 0.9 0.2 0.2 0.0 0.5 0.7 0.1 0.0 0.4 0.6 0.3 0.0 0.2 0.4 1.1 0.0 0.1 0.2 0.3 0.3 0.0 0.0 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.6 2.0 0.1 0.0 0.4 3.3 5.8 0.9 0.0 0.2 0.3 0.4 0.2 0.3 0.2 0.1 0.3 5.1 0.3 0.4 0.7 0.2 0.1 0.2 0.1 0.1 0.2 0.2 0.1 0.1 0.4 0.2 0.2 1.0 0.5 0.2 0.4 0.2 0.1 0.6 1.4 0.4 0.7 0.5 0.7 0.6 1.1 0.6 0.3 1.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.1 0.0 0.4 0.1 0.0 0.4 0.0 0.1 7.3 31.3 0.0 0.0 0.0 209.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.0 0.0 0.2 0.0 30.5 0.0 1.1 0.0 0.0 6.9 0.0 0.0 0.0 1.5 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.3 0.0 1.0 0.0 11.4 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.2 ATP6V1C2 "ATP6C2, VMA5" ENSG00000143882 "ATPase H+ transporting V1 subunit C2" Q8NEY4 2 10721100-10785110 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 80.3;salivary gland: 103.2;skin 1: 87.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 147.2;Distal tubular cells: 45.0;Enteroendocrine cells: 41.5;Glandular and luminal cells: 73.4;Ionocytes: 93.6;Syncytiotrophoblasts: 169.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "BEWO: 78.4;SK-BR-3: 27.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034734, HPA067305" Approved Uncertain Mitochondria NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA034734: AB_2674305, HPA067305: AB_2732763" "unprognostic (2.29e-1)" "unprognostic (1.86e-1)" "unprognostic (1.15e-2)" "unprognostic (6.55e-3)" "unprognostic (2.69e-2)" "unprognostic (2.20e-2)" "unprognostic (7.03e-3)" "unprognostic (8.53e-2)" "unprognostic (1.29e-1)" "unprognostic (2.11e-2)" "unprognostic (6.77e-2)" "unprognostic (2.73e-2)" "prognostic unfavorable (1.12e-11)" "unprognostic (6.17e-2)" "unprognostic (3.30e-1)" "unprognostic (2.37e-1)" "unprognostic (8.27e-2)" 3.4 4.0 1.4 1.7 2.1 4.3 5.7 0.7 1.4 57.5 0.9 2.4 0.9 4.7 80.3 18.3 2.9 0.9 3.0 1.8 0.8 43.3 6.0 2.8 2.0 0.7 0.8 2.9 3.8 1.2 23.5 36.7 0.6 5.1 2.5 1.6 103.2 6.8 1.0 87.6 2.7 0.2 0.6 4.0 2.4 2.0 0.9 0.5 3.8 0.0 5.0 2.0 19.0 1.6 0.6 0.9 2.4 2.7 0.0 0.0 78.4 1.1 0.0 0.0 0.0 1.5 1.9 1.9 1.3 0.0 1.2 1.2 1.3 0.1 0.1 1.1 2.6 0.9 1.4 2.7 0.0 1.8 1.0 0.0 0.3 0.0 0.0 1.8 0.0 0.6 0.9 3.6 0.0 2.1 0.7 2.9 1.8 1.1 0.8 1.6 1.4 5.5 0.0 1.7 1.9 2.3 0.7 27.2 0.8 10.0 2.4 4.0 0.4 0.9 1.8 1.1 1.1 6.2 2.5 1.1 1.1 1.5 0.8 0.0 0.1 0.1 0.3 0.3 0.2 0.1 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.2 1.4 2.1 0.7 1.4 1.8 0.8 0.7 0.8 0.6 0.6 0.9 1.6 13.6 0.0 2.6 0.3 1.0 0.4 3.7 2.8 1.2 0.0 1.4 1.8 0.9 0.0 6.6 7.3 0.0 147.2 0.8 0.3 45.0 0.1 0.7 31.3 13.4 1.4 41.5 0.0 2.4 0.2 33.0 2.7 1.1 73.4 2.5 0.3 0.0 0.2 13.8 0.0 1.2 0.2 93.6 0.8 0.8 0.4 0.6 0.9 0.0 2.8 0.0 0.0 0.0 0.5 1.3 0.2 0.1 0.0 4.0 1.1 0.0 1.1 4.4 0.0 0.0 0.7 1.2 0.2 1.2 0.6 2.4 169.1 1.0 0.3 0.8 0.4 ATP6V1G3 "ATP6G3, Vma10" ENSG00000151418 "ATPase H+ transporting V1 subunit G3" Q96LB4 1 198523222-198540945 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "kidney: 59.3" "Cell type enriched" "Detected in some" 48 "Distal tubular cells: 444.1" "Cancer enriched" "Detected in single" 140 "renal cancer: 11.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 1.5;BJ hTERT+: 1.1;fHDF/TERT166: 4.4;hTERT-RPE1: 1.8;U-2197: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA028701 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "HPA028701: AB_10611681" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 59.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.8 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.5 1.1 0.8 0.3 0.0 0.0 0.0 0.2 4.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.5 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.2 0.0 0.0 0.0 0.0 444.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 AVP "ADH, ARVP" ENSG00000101200 "Arginine vasopressin" P01185 20 3082556-3084724 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Hormone, Vasoactive, Vasoconstrictor" "Diabetes insipidus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1308 "brain: 7951.2" "Group enriched" "Detected in some" 6 "Late spermatids: 26.2;Proximal tubular cells: 46.6" "Not detected" "Not detected" "Region enriched" "Detected in many" 131 "hypothalamus: 7951.2" "Immune cell enriched" "Detected in single" 6 "eosinophil: 2.7" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.7" "Cell line enriched" "Detected in single" 13 "NB-4: 2.3" "Region enriched" "Detected in many" 10 "hypothalamus: 232.9" "Group enriched" "Detected in many" 337 "basal ganglia: 815.6;hypothalamus: 743.3" "CAB025318, HPA071892" Enhanced Supported "Secreted to blood" NA NA 19300 "Cluster 49: Eosinophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 24: NB-4 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB025318: , HPA071892: AB_2732190" "unprognostic (1.15e-1)" "unprognostic (2.61e-1)" 0.3 0.3 24.5 0.0 7.0 0.8 0.2 1.2 60.5 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.3 1.6 7951.2 1.5 0.3 0.1 0.0 0.2 0.7 0.1 0.1 0.0 6.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.1 1.7 0.1 0.0 1.0 0.0 0.0 1.4 10.8 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 24.5 7.0 1.2 60.5 1.6 7951.2 0.2 0.7 0.3 1.0 10.8 0.5 0.1 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 1.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 0.0 5.7 0.0 0.2 0.0 0.0 4.2 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.1 0.0 5.0 0.2 0.0 0.0 0.0 0.3 26.2 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.3 46.6 0.0 0.1 0.0 0.0 0.0 0.2 2.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 AXDND1 "C1orf125, FLJ32940" ENSG00000162779 "Axonemal dynein light chain domain containing 1" Q5T1B0 1 179365720-179554735 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "testis: 15.7" "Group enriched" "Detected in some" 4 "Early spermatids: 226.5;Late spermatids: 247.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA071114 Enhanced NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA071114: AB_2686345" "unprognostic (1.67e-2)" "unprognostic (8.37e-2)" "unprognostic (2.81e-2)" "unprognostic (1.05e-1)" "unprognostic (3.34e-1)" "unprognostic (1.73e-1)" "unprognostic (3.78e-4)" "unprognostic (2.62e-1)" "unprognostic (1.75e-1)" "unprognostic (6.99e-3)" "unprognostic (2.09e-2)" "unprognostic (1.31e-1)" "unprognostic (5.17e-3)" "unprognostic (1.92e-1)" "unprognostic (5.48e-2)" "unprognostic (5.04e-2)" "unprognostic (2.25e-1)" 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.2 15.7 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.2 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.2 0.4 0.2 0.3 0.2 0.2 0.1 0.0 0.5 8.8 0.3 0.0 0.1 0.1 0.0 0.3 0.1 0.3 0.8 0.0 0.8 0.0 2.1 0.1 0.1 16.3 0.0 0.2 226.5 3.1 0.3 0.2 0.0 0.0 3.1 0.2 0.3 0.1 31.6 0.3 0.0 0.2 0.0 0.0 0.1 0.0 3.2 1.5 0.0 0.0 0.0 247.2 1.5 0.5 0.0 1.0 0.0 0.6 0.0 2.0 2.5 0.6 3.8 1.9 0.1 0.1 2.0 0.1 3.2 0.7 0.0 0.0 0.2 50.2 4.3 0.0 0.0 0.1 0.2 0.6 6.1 0.2 AZGP1 "ZA2G, ZAG" ENSG00000160862 "Alpha-2-glycoprotein 1, zinc-binding" P25311 7 99966720-99976042 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 2809.6;salivary gland: 3847.3" "Cell type enhanced" "Detected in many" "Breast glandular cells: 1315.5;Breast myoepithelial cells: 704.8;Hepatocytes: 4270.8;Ionocytes: 901.3;Prostatic glandular cells: 1691.9;Urothelial cells: 674.2" "Group enriched" "Detected in many" 12 "breast cancer: 412.6;liver cancer: 273.6;prostate cancer: 469.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 56.6;OE19: 158.9;RPMI-8226: 130.4;T-47d: 41.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012582, HPA012876, CAB016087, CAB032276" Enhanced Approved Nucleoplasm,Vesicles "Secreted to blood" NA NA 55200000000 74000000000 "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" Vesicles Nucleoplasm "CAB016087: AB_667849, CAB032276: AB_2062580, HPA012582: AB_1845226, HPA012876: " "unprognostic (8.14e-2)" "unprognostic (1.50e-1)" "unprognostic (3.41e-1)" "unprognostic (5.42e-3)" "unprognostic (4.98e-2)" "unprognostic (5.74e-3)" "prognostic favorable (2.90e-4)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (2.19e-1)" "unprognostic (2.35e-2)" "unprognostic (1.79e-1)" "prognostic favorable (1.53e-4)" "unprognostic (2.18e-1)" "unprognostic (2.08e-2)" "unprognostic (9.80e-2)" "unprognostic (3.51e-3)" 128.6 3.9 17.1 2.7 28.8 0.4 1061.4 23.1 18.8 3.4 16.0 6.7 30.9 1.5 2.5 22.0 3.0 38.7 114.7 14.9 22.2 326.8 2809.6 14.8 0.4 20.2 23.3 6.0 752.1 0.1 1.3 0.5 27.1 1051.4 4.2 3.6 3847.3 40.2 1.7 206.8 28.6 0.3 14.0 1.4 315.2 25.9 21.4 0.8 1.9 2.3 1.5 5.8 7.5 24.5 0.2 0.0 0.0 0.0 11.3 0.0 5.5 0.0 0.0 0.0 0.0 0.1 4.0 14.2 0.7 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.1 0.3 0.1 56.6 4.9 1.5 0.1 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.3 29.9 0.0 0.0 0.0 5.1 0.2 158.9 0.0 0.0 1.7 130.4 0.0 0.0 0.0 2.0 1.0 25.4 13.0 0.0 41.8 0.0 0.0 0.5 0.1 1.8 0.9 1.9 0.8 0.4 0.0 0.5 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 28.8 23.1 18.8 14.9 22.2 20.2 23.3 27.1 14.0 21.4 24.5 9.9 22.4 276.8 0.0 14.7 4.2 422.1 25.3 0.0 0.0 1315.5 704.8 115.9 451.8 63.0 5.5 2.1 0.0 10.4 5.5 46.9 11.7 1.9 1.4 1.2 14.2 12.4 85.5 0.1 254.2 0.0 7.7 94.8 5.5 3.8 1.2 65.3 4270.8 0.0 0.0 0.1 13.1 901.3 93.1 0.7 4.2 0.9 14.8 62.2 1.0 2.0 23.7 0.0 7.5 7.3 221.5 6.4 0.0 0.3 1691.9 15.3 596.1 6.3 0.3 0.0 0.0 11.9 7.4 0.4 9.9 9.7 0.0 12.3 0.1 12.6 674.2 B3GNT4 "B3GN-T4, beta3Gn-T4" ENSG00000176383 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4" Q9C0J1 12 122203681-122208952 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9;skin 1: 3.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 3.3;Excitatory neurons: 3.2;Proximal tubular cells: 9.7;Spermatogonia: 2.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 5.1;hTCEpi: 4.0;T-47d: 4.2;U-266/84: 3.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA055261 Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria Nucleoli "HPA055261: AB_2682765" "unprognostic (1.67e-1)" "unprognostic (1.66e-1)" "unprognostic (1.27e-1)" "unprognostic (2.36e-1)" "unprognostic (1.10e-2)" "unprognostic (2.60e-2)" "unprognostic (1.32e-3)" "unprognostic (1.98e-1)" "unprognostic (3.44e-2)" "unprognostic (1.21e-1)" "unprognostic (3.82e-2)" "unprognostic (3.69e-1)" "prognostic unfavorable (3.52e-6)" "unprognostic (1.24e-1)" "unprognostic (2.79e-1)" "unprognostic (8.97e-2)" "unprognostic (9.47e-2)" 0.2 0.7 2.3 0.1 2.6 1.5 0.2 4.9 3.1 0.3 0.0 0.3 0.2 0.1 0.0 1.3 0.6 0.2 0.1 3.8 0.5 2.7 0.4 0.3 0.1 0.0 0.0 0.2 0.3 0.3 1.4 0.1 0.0 0.4 0.0 0.5 0.5 0.0 0.2 3.1 0.3 0.0 0.0 0.5 0.3 1.6 0.9 0.0 0.4 0.0 0.1 0.1 0.5 1.2 3.4 0.6 0.2 1.4 0.1 0.1 0.6 0.1 0.0 0.2 0.3 2.2 0.3 0.3 0.5 0.0 0.2 1.3 1.7 1.2 0.1 5.1 1.9 0.1 1.3 0.2 0.4 0.5 0.7 0.3 4.0 0.1 0.2 0.5 0.0 1.3 1.0 0.4 0.0 3.2 0.0 0.5 0.4 0.1 1.4 0.2 0.4 0.7 0.5 0.4 0.8 1.1 0.9 0.7 0.4 0.5 4.2 0.1 0.1 0.3 1.7 0.4 0.2 0.4 3.6 0.8 0.3 0.5 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 2.3 2.6 4.9 3.1 3.8 0.5 0.0 0.0 0.0 0.0 0.9 1.2 0.4 0.0 1.8 0.7 0.3 1.3 0.7 3.3 0.6 0.2 0.7 0.8 0.5 0.0 1.1 0.0 0.0 0.5 0.5 0.6 1.9 1.0 0.4 0.6 0.3 0.3 0.0 0.0 3.2 0.2 1.1 0.3 0.0 0.8 0.0 0.1 0.4 0.0 0.2 0.0 1.4 0.0 2.0 0.6 0.6 0.1 0.3 0.3 0.0 1.9 0.0 0.2 0.0 0.5 0.6 0.4 1.3 0.0 0.4 0.3 0.1 9.7 1.1 0.2 0.0 0.5 0.2 0.8 2.9 0.8 1.4 0.5 0.4 0.1 0.3 0.4 BAIAP2L2 "FLJ22582, pinkbar" ENSG00000128298 "BAR/IMD domain containing adaptor protein 2 like 2" Q6UXY1 22 38084652-38111015 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 98.6;kidney: 42.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 68.2;Intestinal goblet cells: 58.4;Oligodendrocytes: 31.0;Paneth cells: 32.6;Proximal enterocytes: 125.8;Undifferentiated cells: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 14.1;OE19: 44.2;RPTEC TERT1: 27.3;SK-MEL-30: 38.4;WM-115: 29.8" "Region enhanced" "Detected in many" "olfactory bulb: 3.7" "Low region specificity" "Detected in many" HPA003043 Approved NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" "HPA003043: AB_2227864" "unprognostic (2.15e-1)" "unprognostic (4.23e-2)" "unprognostic (9.82e-2)" "unprognostic (5.91e-2)" "unprognostic (7.75e-2)" "unprognostic (1.75e-1)" "unprognostic (2.57e-3)" "unprognostic (1.37e-3)" "unprognostic (2.30e-2)" "unprognostic (2.14e-1)" "unprognostic (1.21e-1)" "unprognostic (1.88e-3)" "unprognostic (1.77e-1)" "unprognostic (5.73e-2)" "unprognostic (1.27e-1)" "unprognostic (4.23e-2)" "unprognostic (4.51e-2)" 2.5 1.1 3.1 2.8 3.0 0.1 1.8 2.6 6.1 3.7 2.8 41.0 98.6 2.1 0.4 9.7 1.9 14.9 0.8 3.1 2.6 42.5 3.7 0.9 0.3 2.8 2.8 1.5 2.7 0.1 3.5 0.2 2.9 2.5 12.7 0.4 1.9 0.3 1.2 2.4 81.6 0.8 2.6 1.4 8.5 5.9 2.7 0.6 3.1 0.1 0.4 1.2 3.4 3.7 0.2 12.3 0.0 0.0 0.3 1.9 1.5 3.0 0.0 0.0 0.2 9.6 0.8 0.2 4.6 2.7 0.0 1.6 0.0 0.4 0.0 0.3 0.4 0.9 0.0 14.1 0.6 0.0 0.8 0.3 0.7 7.0 0.5 0.0 0.0 0.5 0.4 0.0 0.1 0.1 0.6 0.3 1.1 44.2 0.0 0.4 0.0 0.8 27.3 0.1 0.2 0.2 0.0 5.3 38.4 0.1 0.3 0.2 0.1 0.1 0.4 0.0 0.0 0.9 0.1 0.2 0.0 0.0 29.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 3.0 2.6 6.1 3.1 2.6 2.8 2.8 2.9 2.6 2.7 3.7 0.2 0.0 0.0 7.8 0.5 0.8 0.2 1.0 1.2 2.8 0.3 0.3 1.1 17.2 0.2 0.0 2.1 0.3 0.2 68.2 1.9 0.6 0.7 2.2 3.8 0.3 27.6 0.0 17.2 0.0 1.2 0.8 21.9 12.8 0.0 0.5 0.4 0.9 0.5 6.7 13.1 58.4 0.0 0.3 0.2 0.5 1.2 0.2 5.4 5.6 0.1 0.2 1.0 7.5 31.0 5.4 32.6 1.2 0.3 0.2 125.8 19.1 0.1 1.4 0.0 0.2 1.3 1.3 4.4 1.4 1.1 0.4 0.5 0.3 41.4 0.5 BCL6B "BAZF, ZBTB28, ZNF62" ENSG00000161940 "BCL6B transcription repressor" Q8N143 17 7023050-7030290 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 37.8;Endothelial cells: 45.0;Hepatic stellate cells: 23.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 18.2;HMC-1: 53.2;HUVEC TERT2: 96.2;TIME: 38.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA059147, HPA075112" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Vesicles, Plasma membrane" "HPA059147: AB_2683928, HPA075112: AB_2732279" "unprognostic (5.61e-2)" "unprognostic (9.43e-3)" "unprognostic (2.33e-2)" "unprognostic (2.12e-1)" "unprognostic (1.40e-1)" "prognostic favorable (8.56e-5)" "unprognostic (2.81e-1)" "unprognostic (2.28e-2)" "unprognostic (4.81e-2)" "unprognostic (1.80e-1)" "unprognostic (6.10e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (4.04e-4)" "unprognostic (7.14e-2)" "unprognostic (1.11e-1)" "unprognostic (4.29e-2)" "unprognostic (4.26e-2)" 29.8 5.6 8.1 5.7 7.0 0.1 15.4 6.2 9.2 5.7 4.4 4.4 3.2 7.7 0.7 3.8 5.1 13.4 23.3 6.5 6.9 13.4 4.0 28.9 5.5 7.8 7.1 2.9 3.8 3.1 5.5 19.9 7.3 4.5 2.2 0.6 4.0 3.5 11.5 4.4 4.9 7.7 6.6 13.0 4.3 2.0 10.1 2.0 12.0 14.7 2.1 7.9 4.8 6.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 18.2 0.0 0.0 0.5 0.0 53.2 0.0 0.0 0.0 0.1 0.0 96.2 0.2 3.4 0.4 0.0 0.0 0.2 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.2 38.2 0.8 0.2 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.2 9.2 6.5 6.9 7.8 7.1 7.3 6.6 10.1 6.7 37.8 3.2 4.2 0.0 0.5 2.2 0.0 0.0 0.0 0.0 0.2 0.3 2.9 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.3 45.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.1 23.6 0.2 0.1 0.0 0.0 0.2 0.0 1.9 2.3 0.0 0.0 0.3 3.6 4.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.4 0.0 0.1 0.0 0.2 0.0 0.9 0.8 0.6 1.5 0.4 1.3 0.1 0.2 0.9 0.0 0.5 BHMT BHMT1 ENSG00000145692 "Betaine--homocysteine S-methyltransferase" Q93088 5 79111809-79132288 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 83 "kidney: 778.9;liver: 1141.8" "Group enriched" "Detected in some" 10 "Hepatocytes: 604.2;Proximal tubular cells: 996.1" "Group enriched" "Detected in some" 4 "liver cancer: 90.6;renal cancer: 50.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 3.6;NTERA-2: 1.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA038285, HPA058310" Enhanced Supported Cytosol No NA 10000000 "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA038285: AB_10675791, HPA058310: AB_2683675" "unprognostic (2.61e-2)" "unprognostic (4.12e-1)" "unprognostic (4.45e-1)" "unprognostic (4.14e-3)" "unprognostic (5.62e-2)" "unprognostic (4.14e-1)" "prognostic favorable (7.32e-4)" "unprognostic (5.33e-2)" "unprognostic (1.51e-1)" "unprognostic (1.13e-1)" "unprognostic (9.66e-4)" "unprognostic (6.42e-2)" "unprognostic (8.26e-3)" "unprognostic (1.77e-1)" "unprognostic (3.22e-1)" "unprognostic (3.60e-2)" "unprognostic (2.30e-3)" 0.7 0.3 0.3 0.0 0.8 0.0 0.5 0.0 0.5 0.3 0.1 0.6 1.2 0.2 1.8 0.1 0.2 0.2 0.2 0.5 0.3 778.9 1141.8 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.5 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.1 3.2 0.3 0.3 0.5 0.4 0.0 0.0 11.6 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.6 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.5 0.5 0.3 0.1 0.2 0.1 0.1 0.3 0.2 0.1 0.0 0.0 1.0 5.2 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.3 4.3 0.0 16.5 0.0 0.0 0.0 0.0 78.2 0.0 0.5 0.1 0.8 0.8 0.0 13.5 0.9 0.0 0.1 0.1 8.2 0.2 0.0 0.1 8.9 604.2 0.0 0.0 0.2 0.4 0.0 12.2 0.0 0.5 0.9 3.5 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 2.6 0.0 0.0 0.0 996.1 0.0 0.4 0.0 0.2 0.1 0.2 1.0 0.0 0.0 0.1 4.2 0.5 0.1 0.3 BHMT2 ENSG00000132840 "Betaine--homocysteine S-methyltransferase 2" Q9H2M3 5 79069767-79090069 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "kidney: 333.1;liver: 429.9" "Cell type enhanced" "Detected in many" "Distal tubular cells: 95.9;Hepatocytes: 201.2;Proximal tubular cells: 408.6" "Group enriched" "Detected in many" 14 "liver cancer: 79.6;renal cancer: 52.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 17.5;Hep G2: 78.2;hTEC/SVTERT24-B: 46.0;U-87 MG: 18.6" "Not detected" "Not detected" HPA044573 Enhanced NA NA 1900000 "Cluster 17: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA044573: AB_10795044" "unprognostic (5.03e-2)" "unprognostic (4.42e-2)" "unprognostic (2.60e-2)" "unprognostic (3.76e-2)" "unprognostic (4.40e-2)" "unprognostic (2.90e-3)" "unprognostic (1.56e-2)" "unprognostic (1.95e-1)" "unprognostic (1.87e-2)" "unprognostic (2.45e-3)" "unprognostic (1.41e-2)" "unprognostic (1.02e-1)" "unprognostic (1.76e-2)" "unprognostic (5.05e-2)" "unprognostic (1.49e-1)" "unprognostic (1.60e-1)" "unprognostic (1.06e-3)" 31.3 16.6 5.6 3.0 6.0 0.3 15.5 4.5 5.0 8.5 14.2 15.7 1.7 12.1 37.6 7.6 7.6 7.4 13.6 4.9 7.3 333.1 429.9 3.1 1.3 5.2 7.0 7.8 1.8 0.5 12.3 0.4 6.2 12.0 2.4 1.3 2.1 14.4 10.2 2.4 6.1 13.0 4.7 0.6 9.1 3.8 6.9 0.9 18.8 4.8 1.0 18.1 3.8 4.7 0.0 0.2 0.1 0.1 8.5 6.0 2.8 7.8 17.5 4.0 7.7 0.0 0.1 0.1 0.1 9.7 0.0 0.1 0.0 0.0 5.7 0.0 0.0 0.4 0.4 78.2 6.6 0.4 0.1 7.3 0.0 46.0 0.0 7.9 0.0 0.0 0.4 0.4 1.1 0.0 0.1 0.3 0.1 0.0 0.2 0.1 0.5 0.1 0.0 0.2 2.2 0.1 0.5 0.0 0.1 0.5 0.1 0.2 0.0 0.3 0.1 0.3 0.1 0.1 0.1 0.3 18.6 0.4 0.1 0.7 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.8 0.3 0.0 0.1 0.0 0.0 5.6 6.0 4.5 5.0 4.9 7.3 5.2 7.0 6.2 4.7 6.9 4.7 1.4 6.4 0.5 6.2 1.2 0.8 0.4 0.1 0.0 1.5 0.2 0.1 4.4 1.5 0.0 46.0 2.1 0.2 0.0 0.0 95.9 0.1 0.5 0.4 11.7 2.9 1.2 2.7 4.1 0.0 0.4 17.3 0.0 0.4 0.0 4.5 2.5 201.2 0.3 0.0 0.6 0.1 0.0 4.4 1.2 1.3 27.4 2.5 0.0 11.2 0.3 4.2 0.0 2.0 0.6 0.0 0.0 37.2 0.1 0.4 0.0 408.6 0.1 1.2 6.6 6.2 3.1 0.4 0.5 0.1 1.0 0.3 2.2 30.0 0.0 1.0 BPHL "Bph-rp, MCNAA, VACVase" ENSG00000137274 "Biphenyl hydrolase like" Q86WA6 6 3118374-3153578 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 110.4;liver: 84.8" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 99.7;Proximal tubular cells: 336.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036752, HPA036753" Enhanced Approved Mitochondria NA NA 14000 "Cluster 44: Non-specific - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA036752: AB_10673662, HPA036753: AB_2675291" "unprognostic (2.93e-1)" "unprognostic (1.29e-1)" "unprognostic (8.88e-2)" "unprognostic (1.11e-1)" "unprognostic (3.72e-3)" "unprognostic (1.84e-1)" "unprognostic (8.65e-2)" "unprognostic (3.14e-2)" "unprognostic (1.94e-1)" "prognostic favorable (5.97e-4)" "unprognostic (4.59e-2)" "unprognostic (9.46e-3)" "prognostic favorable (5.16e-7)" "unprognostic (1.60e-2)" "unprognostic (1.51e-2)" "unprognostic (6.98e-2)" "unprognostic (5.20e-2)" 24.1 15.3 9.4 3.9 9.8 3.5 11.2 9.5 14.5 9.3 11.8 10.6 33.8 7.0 28.8 13.2 11.1 8.9 11.6 10.1 10.8 110.4 84.8 5.2 4.4 9.8 10.2 6.5 11.5 10.8 12.7 5.0 10.7 6.8 9.4 4.2 11.3 4.7 15.5 11.2 32.8 5.8 8.6 3.9 10.0 5.0 9.8 4.8 5.5 12.5 5.9 9.0 9.1 10.8 12.0 13.8 26.8 30.6 22.5 16.2 10.2 7.1 8.7 8.6 11.4 12.4 15.3 18.6 19.7 9.2 21.4 22.1 11.7 8.0 7.6 24.8 10.5 2.7 5.4 21.8 7.9 6.3 1.8 16.9 14.1 6.3 6.0 17.7 15.5 18.8 7.2 3.0 19.9 18.2 14.8 8.3 22.5 21.1 21.9 16.1 17.7 27.9 19.7 30.3 31.7 23.3 13.2 9.0 58.4 39.4 25.6 2.2 7.7 12.5 3.4 13.1 4.9 8.6 27.8 20.4 3.5 4.0 18.4 13.6 9.8 0.0 8.2 12.9 10.9 17.5 9.7 8.4 15.3 12.8 9.1 12.7 0.6 14.6 7.8 8.4 5.4 7.5 9.4 9.8 9.5 14.5 10.1 10.8 9.8 10.2 10.7 8.6 9.8 10.8 15.9 6.4 9.3 11.1 8.2 8.9 8.6 26.0 10.8 11.1 15.1 19.0 4.8 31.5 19.3 16.5 20.9 28.6 5.6 13.6 70.5 28.1 0.5 13.6 14.0 9.1 16.1 6.9 9.3 13.5 32.2 12.2 11.2 8.2 2.5 31.8 6.1 70.9 23.7 16.8 12.8 14.9 38.7 2.2 8.3 1.6 14.9 8.0 32.0 10.3 13.9 12.2 7.2 9.0 4.7 19.6 14.8 13.9 4.5 8.4 99.7 336.3 38.2 6.9 6.6 19.0 12.5 6.8 20.6 13.9 9.2 14.0 7.6 32.9 19.0 8.1 C10orf67 "bA215C7.4, C10orf115, LINC01552, MGC46732" ENSG00000179133 "Chromosome 10 open reading frame 67" Q8IYJ2 10 23202696-23344845 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 5.1;fallopian tube: 4.8;testis: 12.4" "Group enriched" "Detected in some" 5 "Alveolar cells type 1: 38.5;Early spermatids: 40.2;Endometrial ciliated cells: 18.2;Late spermatids: 32.8;Proximal tubular cells: 17.9;Respiratory ciliated cells: 35.7;Spermatocytes: 70.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HaCaT: 3.0;SiHa: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA038131 Approved Approved Vesicles,Microtubules,Mitochondria NA No "Cluster 35: T-regs - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Vesicles, Microtubules, Mitochondria" "HPA038131: AB_10670658" "unprognostic (4.76e-4)" "unprognostic (2.38e-1)" "unprognostic (3.75e-2)" "unprognostic (2.92e-2)" "unprognostic (9.67e-3)" "unprognostic (1.91e-1)" "unprognostic (1.54e-1)" "unprognostic (1.78e-2)" "unprognostic (8.56e-2)" "unprognostic (1.78e-1)" "unprognostic (1.24e-2)" "unprognostic (2.46e-3)" "unprognostic (3.98e-1)" "unprognostic (3.59e-2)" "unprognostic (3.84e-3)" "unprognostic (9.58e-2)" 0.0 0.2 1.5 0.2 1.4 0.3 0.1 0.9 1.6 0.1 5.1 0.1 0.5 0.2 1.4 0.1 4.8 0.2 0.7 1.7 1.3 3.5 0.4 2.9 0.3 2.0 2.2 0.5 0.2 0.4 1.2 0.1 1.5 0.0 0.0 0.9 0.1 0.1 0.5 1.3 0.3 0.0 1.3 0.2 0.1 12.4 1.9 0.0 0.6 0.1 0.1 0.0 0.0 2.0 0.7 0.1 0.9 0.1 0.0 0.2 0.3 0.1 0.0 0.9 0.8 0.2 1.3 0.1 0.1 0.8 0.1 3.0 0.1 0.3 0.8 0.3 0.2 0.3 0.7 0.2 0.5 0.1 0.2 0.2 1.0 0.3 0.4 0.1 0.0 0.1 0.3 0.5 0.0 0.3 0.1 0.2 0.5 0.0 0.1 0.1 0.1 0.1 0.7 0.2 0.5 0.2 3.9 0.1 0.0 0.1 0.2 0.2 0.2 0.2 0.8 0.2 0.1 0.5 0.1 0.0 1.1 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.1 0.2 0.3 0.2 0.0 0.3 0.2 0.2 0.0 0.2 0.1 0.2 1.2 0.0 1.5 1.4 0.9 1.6 1.7 1.3 2.0 2.2 1.5 1.3 1.9 2.0 0.0 38.5 2.4 0.3 0.0 2.8 0.1 1.9 0.0 0.4 0.0 0.0 1.8 0.0 2.5 0.0 0.0 0.0 0.0 0.0 1.9 0.2 40.2 18.2 0.2 0.1 0.0 0.0 4.7 0.2 0.0 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 32.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 2.2 0.2 0.0 0.7 0.0 0.0 0.0 17.9 35.7 1.6 6.6 0.0 0.1 70.1 5.2 0.0 1.3 0.0 0.3 0.5 0.1 0.0 C11orf54 PTD012 ENSG00000182919 "Chromosome 11 open reading frame 54" Q9H0W9 11 93741591-93764749 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "kidney: 569.9;liver: 258.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 370.4;Proximal tubular cells: 1136.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040088, HPA040511" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA 1300000 "Cluster 5: Granulocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear bodies" Nucleoplasm "HPA040088: AB_10795518, HPA040511: AB_10795369" "unprognostic (3.32e-2)" "unprognostic (3.51e-1)" "unprognostic (1.67e-3)" "unprognostic (2.62e-2)" "unprognostic (1.82e-2)" "unprognostic (1.90e-2)" "unprognostic (2.81e-2)" "unprognostic (1.01e-1)" "unprognostic (2.46e-2)" "unprognostic (2.87e-1)" "unprognostic (2.10e-3)" "unprognostic (1.58e-1)" "prognostic favorable (5.06e-6)" "unprognostic (2.19e-1)" "unprognostic (6.10e-2)" "unprognostic (2.41e-2)" "unprognostic (6.53e-3)" 20.1 24.6 10.2 19.1 16.4 7.4 31.4 15.2 14.8 20.7 18.0 40.8 53.0 21.7 19.6 17.6 32.3 47.2 21.5 9.5 14.8 569.9 258.8 30.3 21.5 18.3 12.9 30.1 51.6 20.9 16.7 25.3 16.5 39.6 43.8 20.7 28.9 25.0 41.8 21.2 51.5 20.8 13.0 17.3 37.9 19.8 12.9 28.1 35.9 54.7 23.4 17.0 12.9 25.2 9.4 13.5 30.9 18.3 23.5 26.8 36.1 13.8 23.6 13.8 19.0 5.6 52.9 39.4 85.5 25.6 14.4 22.2 37.5 10.0 19.4 39.9 11.4 21.7 34.9 26.5 27.7 20.7 11.0 24.7 17.0 24.7 16.6 34.8 21.6 26.2 29.6 26.6 12.8 8.0 33.0 23.7 10.5 64.9 22.1 31.4 40.8 62.2 74.6 19.6 15.2 20.2 23.0 28.2 27.7 22.7 65.9 13.4 13.5 13.0 10.0 22.5 6.6 12.0 38.2 37.8 9.8 29.2 23.3 75.0 30.0 74.0 21.7 21.5 22.3 27.1 22.1 24.7 23.0 23.0 27.0 23.7 100.9 24.8 19.0 31.9 31.5 18.8 10.2 16.4 15.2 14.8 9.5 14.8 18.3 12.9 16.5 13.0 12.9 25.2 25.1 64.1 54.7 28.1 27.4 5.5 10.6 18.4 21.1 18.0 21.6 14.6 34.7 190.1 33.5 47.8 16.7 51.4 21.6 53.6 178.1 17.4 14.4 34.2 20.5 18.3 22.2 23.1 23.7 13.9 14.8 23.9 32.6 43.6 15.2 40.2 29.6 370.4 17.5 15.2 27.8 37.1 28.5 29.2 7.2 6.4 25.7 22.2 8.8 15.9 18.2 17.0 10.3 25.6 37.8 13.1 38.4 23.0 25.7 29.0 75.0 1136.3 36.2 19.7 6.6 28.9 17.0 38.6 17.4 17.6 9.9 62.0 21.1 16.3 35.6 22.9 C11orf86 FLJ22675 ENSG00000173237 "Chromosome 11 open reading frame 86" A6NJI1 11 66975277-66977004 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 68.0" "Group enriched" "Detected in some" 20 "Distal enterocytes: 212.2;Paneth cells: 132.8;Proximal enterocytes: 506.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HeLa: 7.2;SiHa: 24.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA039348 Uncertain NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 20: HeLa - Mitochondria" "Cluster 45: Enterocytes - Digestion" "HPA039348: AB_10673421" "unprognostic (1.54e-2)" "unprognostic (7.67e-3)" "unprognostic (3.02e-2)" "unprognostic (1.20e-1)" "unprognostic (3.90e-4)" "prognostic unfavorable (8.97e-4)" "unprognostic (4.17e-1)" "prognostic unfavorable (6.97e-5)" "prognostic unfavorable (1.02e-5)" "unprognostic (7.04e-2)" "unprognostic (1.51e-1)" "unprognostic (1.69e-2)" "unprognostic (3.58e-3)" 0.1 15.4 0.1 0.6 0.1 0.0 0.1 0.1 0.1 0.0 0.1 10.4 68.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.7 1.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.3 0.1 0.0 6.5 0.0 0.0 0.0 0.0 0.0 64.2 0.7 0.1 0.0 2.1 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 1.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 24.9 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 212.2 0.0 0.2 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 132.8 0.0 0.0 0.0 506.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 8.4 0.2 C11orf97 LINC01171 ENSG00000257057 "Chromosome 11 open reading frame 97" A0A1B0GVM6 11 94512461-94532123 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "fallopian tube: 19.1;testis: 18.2" "Group enriched" "Detected in some" 5 "Early spermatids: 239.3;Endometrial ciliated cells: 258.2;Respiratory ciliated cells: 109.3" "Cancer enhanced" "Detected in some" "endometrial cancer: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (3.62e-3)" "unprognostic (1.29e-1)" "unprognostic (1.22e-1)" "unprognostic (4.18e-1)" "unprognostic (4.70e-1)" "unprognostic (9.64e-3)" "unprognostic (9.44e-3)" "unprognostic (3.86e-3)" 0.0 0.0 1.4 0.0 2.6 0.3 0.0 0.2 1.7 1.2 4.0 0.0 0.0 0.5 0.1 0.0 19.1 0.1 0.0 1.5 1.1 0.9 1.3 2.5 0.0 2.2 2.5 0.0 0.5 0.0 0.2 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 18.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 2.6 0.2 1.7 1.5 1.1 2.2 2.5 1.6 1.9 1.5 1.5 0.0 3.2 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 11.2 0.0 0.0 0.3 0.0 0.1 0.0 0.4 239.3 258.2 1.4 0.6 0.0 0.0 3.4 0.2 0.0 0.5 0.0 3.2 0.0 0.0 0.0 4.5 0.1 0.0 2.0 0.0 0.0 0.0 0.0 34.4 1.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 1.9 0.0 0.0 0.0 18.1 109.3 0.0 0.0 0.0 0.0 37.9 9.6 0.0 0.0 0.0 0.5 0.0 0.0 0.1 C1QA ENSG00000173372 "Complement C1q A chain" P02745 1 22636628-22639678 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 1092.6" "Group enriched" "Detected in many" 9 "Hofbauer cells: 1663.2;Kupffer cells: 5007.4;Macrophages: 1874.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39 "intermediate monocyte: 226.1;non-classical monocyte: 181.7" "Lineage enriched" "Detected in many" 60 "monocytes: 226.1" "Cell line enhanced" "Detected in some" "HMC-1: 2.3;NB-4: 1.4;RPMI-8226: 7.1;SCLC-21H: 3.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002350, CAB009823" Supported "Secreted to blood" NA NA 2700000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009823: AB_2228238, HPA002350: AB_1078552" "unprognostic (1.97e-1)" "unprognostic (1.14e-2)" "unprognostic (1.98e-3)" "unprognostic (3.07e-2)" "unprognostic (6.10e-2)" "unprognostic (2.60e-1)" "unprognostic (1.16e-1)" "unprognostic (2.13e-1)" "unprognostic (1.67e-2)" "unprognostic (1.99e-1)" "unprognostic (4.42e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (1.58e-6)" "unprognostic (1.54e-1)" "unprognostic (2.11e-3)" "unprognostic (2.75e-2)" "unprognostic (7.30e-2)" 375.1 235.6 86.6 134.0 85.6 53.9 95.9 85.8 135.3 75.8 120.0 142.8 172.3 43.1 26.0 58.3 75.6 172.4 74.8 82.9 93.7 56.2 208.8 404.3 532.3 126.7 110.1 37.5 34.3 26.2 46.3 256.3 110.3 47.1 120.2 4.1 48.1 54.6 14.8 21.8 190.1 195.0 107.5 1092.6 90.8 38.2 109.4 100.3 36.5 49.3 68.0 257.5 30.4 131.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.4 0.3 0.0 0.0 0.5 0.2 7.1 0.0 0.0 3.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.4 0.1 0.8 0.0 0.0 0.1 0.1 0.0 0.1 5.2 0.1 0.1 226.1 0.0 0.0 0.1 0.1 3.7 0.0 0.0 0.0 0.5 0.3 181.7 0.0 0.0 9.7 86.6 85.6 85.8 135.3 82.9 93.7 126.7 110.1 110.3 107.5 109.4 131.6 17.4 35.3 55.8 0.0 19.0 18.4 2.3 0.0 2.2 0.4 5.1 24.6 8.9 37.1 18.0 0.0 0.0 8.7 2.7 0.5 0.0 0.0 4.5 0.2 0.5 46.0 1.8 41.0 0.0 0.2 11.3 9.6 0.0 0.2 21.5 0.2 76.1 26.2 1663.2 0.0 0.0 0.1 0.0 5007.4 291.4 9.9 13.1 1874.2 26.6 20.6 16.7 0.3 0.0 0.0 0.1 0.0 0.1 0.4 2.8 1.3 0.1 1.1 15.3 0.8 78.9 7.4 4.6 0.7 2.1 4.2 16.8 18.2 11.8 0.0 0.2 1.3 C1QB ENSG00000173369 "Complement C1q B chain" 1 22652762-22661637 "Human disease related genes, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "lung: 546.4;lymphoid tissue: 990.2" "Group enriched" "Detected in many" 28 "Hofbauer cells: 1451.0;Kupffer cells: 4559.7;Macrophages: 1747.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 71 "intermediate monocyte: 140.6;non-classical monocyte: 101.2" "Lineage enriched" "Detected in many" 85 "monocytes: 140.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052116 Approved "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA052116: AB_2681735" "unprognostic (1.42e-1)" "unprognostic (3.36e-2)" "unprognostic (5.61e-3)" "unprognostic (8.20e-2)" "unprognostic (5.93e-2)" "unprognostic (4.09e-1)" "unprognostic (1.25e-1)" "unprognostic (2.35e-1)" "unprognostic (2.87e-2)" "unprognostic (2.21e-1)" "unprognostic (2.63e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (9.58e-6)" "unprognostic (4.14e-2)" "unprognostic (7.76e-3)" "unprognostic (4.83e-2)" "unprognostic (2.35e-2)" 439.2 229.0 95.8 149.4 94.2 53.5 87.1 97.2 148.7 65.4 132.6 162.0 186.0 27.7 26.4 63.0 50.5 194.9 62.6 89.8 107.7 18.3 243.4 546.4 514.6 161.0 143.3 39.6 40.0 28.5 1.8 249.2 138.4 28.0 146.0 7.8 44.9 51.2 5.3 6.1 186.1 261.4 138.2 990.2 88.0 39.9 142.2 72.0 23.6 38.6 58.4 255.8 1.1 185.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.8 0.4 0.0 0.0 0.5 0.3 0.6 0.0 0.0 0.5 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.8 0.0 0.1 0.1 0.0 0.2 0.0 1.7 0.0 0.0 140.6 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.4 0.8 101.2 0.0 0.0 5.3 95.8 94.2 97.2 148.7 89.8 107.7 161.0 143.3 138.4 138.2 142.2 185.8 13.8 12.8 22.1 0.0 17.1 6.2 2.1 0.0 1.8 1.2 4.9 23.1 5.5 24.3 10.5 3.7 0.0 6.6 2.7 0.6 0.0 0.0 3.3 0.1 0.2 65.9 0.0 32.8 0.1 0.0 9.6 5.9 0.0 0.1 11.4 0.1 52.1 26.0 1451.0 0.0 0.1 0.0 0.0 4559.7 92.1 7.8 8.4 1747.2 0.0 34.7 5.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 2.3 1.0 0.3 1.1 3.6 3.9 59.2 4.0 3.2 0.4 0.9 5.7 4.5 9.6 6.1 0.2 0.0 1.5 C1QC C1QG ENSG00000159189 "Complement C1q C chain" P02747 1 22643633-22648110 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 950.7" "Group enriched" "Detected in many" 7 "Hofbauer cells: 1356.5;Kupffer cells: 2134.6;Macrophages: 1040.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "intermediate monocyte: 57.2" "Lineage enriched" "Detected in single" 541 "monocytes: 57.2" "Cell line enhanced" "Detected in some" "NB-4: 1.0;RPMI-8226: 2.6;U-266/70: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001471, CAB009828" Supported "Secreted to blood" NA NA 513000000 2100000000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009828: AB_2067541, HPA001471: AB_1078553" "unprognostic (2.97e-1)" "unprognostic (6.80e-2)" "unprognostic (2.40e-2)" "unprognostic (1.84e-1)" "unprognostic (7.40e-2)" "unprognostic (2.38e-1)" "unprognostic (1.98e-1)" "unprognostic (1.40e-1)" "unprognostic (1.66e-2)" "unprognostic (7.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (1.06e-1)" "unprognostic (1.63e-3)" "unprognostic (2.21e-2)" "unprognostic (3.73e-2)" 285.2 196.0 60.1 159.7 58.6 43.5 70.5 64.8 97.1 51.9 90.6 133.2 179.9 36.3 13.5 55.3 67.4 155.4 58.6 54.9 75.5 41.2 169.6 290.8 370.2 124.7 105.4 32.1 37.5 22.1 39.6 204.9 105.0 37.8 91.3 3.9 51.6 44.5 12.9 18.3 195.7 164.7 100.4 950.7 94.8 33.9 106.0 75.7 29.2 31.8 50.7 191.8 24.6 159.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 1.0 0.2 0.0 0.0 0.6 0.2 2.6 0.0 0.0 0.4 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 1.0 0.0 0.1 0.1 0.1 0.0 0.0 1.3 0.0 0.0 57.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.4 0.0 0.0 1.2 60.1 58.6 64.8 97.1 54.9 75.5 124.7 105.4 105.0 100.4 106.0 159.3 13.4 6.4 5.2 0.3 13.7 8.9 1.1 0.0 2.8 0.6 4.9 24.5 1.6 15.7 3.1 0.0 0.0 5.8 2.3 0.4 0.0 0.0 3.2 0.0 0.1 34.5 0.0 27.2 0.0 0.2 9.5 4.4 0.0 0.1 5.1 0.1 25.4 6.6 1356.5 0.0 0.1 0.1 0.0 2134.6 202.4 3.6 6.2 1040.7 7.2 29.0 23.6 0.4 0.0 0.0 0.0 0.0 1.1 1.2 0.9 0.4 0.0 0.4 0.7 0.6 46.0 2.5 1.8 0.4 0.8 3.3 6.5 9.9 3.5 0.0 0.0 0.7 C1QTNF12 "ADIPOLIN, C1QDC2, CTRP12, FAM132A, MGC105127" ENSG00000184163 "C1q and TNF related 12" Q5T7M4 1 1242446-1246722 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 6.8;skin 1: 6.6" "Cell type enhanced" "Detected in some" "Adipocytes: 19.5;Extravillous trophoblasts: 11.2;Proximal tubular cells: 45.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "EFO-21: 4.1;U-2 OS: 4.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA024107 Uncertain Approved Vesicles "Secreted to blood" NA NA 38200000 "Cluster 40: NK-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA024107: AB_2101207" "unprognostic (1.10e-2)" "unprognostic (5.68e-3)" "unprognostic (3.45e-1)" "unprognostic (1.24e-2)" "unprognostic (6.60e-3)" "unprognostic (2.43e-1)" "unprognostic (2.67e-3)" "unprognostic (1.01e-2)" "unprognostic (2.58e-1)" "unprognostic (1.05e-2)" "unprognostic (8.02e-3)" "unprognostic (1.10e-2)" "unprognostic (9.68e-3)" "unprognostic (1.48e-1)" "unprognostic (2.47e-1)" "unprognostic (1.09e-1)" "unprognostic (1.20e-1)" 1.3 0.1 0.4 0.2 0.4 0.0 0.7 0.3 0.5 0.5 0.0 3.4 6.8 0.3 0.0 1.3 0.5 0.1 0.8 0.4 0.7 3.4 0.5 0.4 0.0 0.8 0.4 0.2 0.2 0.0 0.3 0.2 0.5 0.3 0.7 0.0 0.3 0.0 0.4 6.6 6.7 0.0 0.4 0.2 0.4 2.4 0.9 0.0 0.4 0.0 0.1 0.3 0.6 0.5 0.1 0.0 0.0 0.3 0.2 0.0 0.8 0.6 0.0 0.0 0.0 0.3 0.2 0.0 4.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.1 0.1 0.4 0.3 0.1 0.1 0.0 0.7 0.0 0.0 0.6 0.1 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.0 4.0 0.0 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.4 0.4 0.3 0.5 0.4 0.7 0.8 0.4 0.5 0.4 0.9 0.5 19.5 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.6 2.9 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 3.9 0.5 0.0 0.6 1.2 0.7 0.0 0.0 0.0 0.8 11.2 0.5 0.0 0.7 2.5 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 45.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.4 0.3 0.0 0.0 C3orf85 FLJ22763 ENSG00000241224 "Chromosome 3 open reading frame 85" A0A1B0GTC6 3 109118252-109151401 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 70.4;kidney: 13.9;liver: 19.8" "Cell type enriched" "Detected in some" 9 "Proximal tubular cells: 169.0" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA 2900000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (9.10e-2)" "unprognostic (9.48e-3)" "unprognostic (3.80e-4)" "unprognostic (1.15e-1)" "unprognostic (6.70e-2)" 0.1 0.0 0.2 0.4 0.4 0.0 0.0 0.5 0.2 0.0 0.0 5.4 70.4 0.1 1.6 0.0 0.0 0.0 0.0 0.1 0.2 13.9 19.8 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.2 0.1 0.0 0.0 0.0 0.0 64.6 0.1 0.1 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.5 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.5 0.5 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 169.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 CACNA1E "BII, CACH6, CACNL1A6, Cav2.3" ENSG00000198216 "Calcium voltage-gated channel subunit alpha1 E" Q15878 1 181317690-181808084 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "brain: 42.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 188.7;Inhibitory neurons: 116.0;Oligodendrocyte precursor cells: 73.9;Oligodendrocytes: 34.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.6;NB-4: 1.0;NTERA-2: 1.1;U-266/70: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042515, CAB079032" Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Actin filaments, Cytosol" "CAB079032: , HPA042515: " "unprognostic (3.96e-3)" "unprognostic (1.89e-1)" "unprognostic (1.05e-2)" "unprognostic (1.54e-5)" "unprognostic (6.56e-2)" "unprognostic (3.16e-2)" "unprognostic (4.30e-3)" "unprognostic (1.18e-1)" "unprognostic (2.40e-1)" "unprognostic (9.48e-3)" "unprognostic (1.04e-1)" "unprognostic (2.06e-1)" "unprognostic (9.85e-7)" "unprognostic (1.74e-2)" "unprognostic (2.07e-2)" "unprognostic (1.16e-1)" "unprognostic (3.75e-2)" 0.0 1.0 33.5 0.6 30.5 1.2 0.0 0.0 34.6 0.0 0.0 0.1 0.0 0.0 1.5 0.2 0.7 0.0 0.3 42.8 3.4 1.3 0.0 0.1 0.4 4.6 6.2 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.2 0.2 9.7 0.4 0.1 1.0 3.8 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.1 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 33.5 30.5 0.0 34.6 42.8 3.4 4.6 6.2 0.9 9.7 3.8 1.1 0.0 0.0 0.0 3.6 0.0 0.1 0.0 0.0 0.0 4.6 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.4 0.0 0.0 188.7 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 116.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 6.5 0.0 0.2 0.0 73.9 34.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 CALML3 CLP ENSG00000178363 "Calmodulin like 3" P27482 10 5524961-5526771 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 507.1;skin 1: 179.0;vagina: 200.8" "Cell type enriched" "Detected in some" 8 "Squamous epithelial cells: 1257.1" "Cancer enhanced" "Detected in many" "cervical cancer: 150.9;head and neck cancer: 196.3" "Region enhanced" "Detected in single" "cerebellum: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "A-431: 21.5;hTCEpi: 8.6;RPMI-8226: 6.0" "Not detected" "Not detected" "CAB010070, HPA044999" Approved NA NA 1200000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "CAB010070: , HPA044999: AB_2679177" "unprognostic (1.02e-3)" "unprognostic (1.18e-2)" "unprognostic (4.33e-2)" "unprognostic (1.37e-1)" "unprognostic (1.29e-2)" "unprognostic (2.16e-1)" "unprognostic (2.93e-1)" "unprognostic (3.11e-1)" "unprognostic (1.02e-2)" "unprognostic (9.64e-2)" "unprognostic (1.35e-1)" "unprognostic (2.73e-2)" "unprognostic (1.71e-1)" "unprognostic (2.56e-1)" "unprognostic (1.65e-1)" "unprognostic (4.43e-3)" 0.5 0.1 0.2 0.0 0.2 0.0 5.4 1.5 0.1 107.9 0.0 0.1 0.0 0.1 0.1 507.1 1.2 0.0 0.1 0.0 0.3 17.3 1.6 0.0 0.0 0.5 0.3 0.1 0.2 0.0 0.3 0.0 0.2 2.9 0.0 0.0 121.0 0.1 1.0 179.0 0.2 0.0 0.0 0.1 0.3 1.7 0.7 79.5 0.1 0.0 39.8 0.2 200.8 0.0 21.5 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 8.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.5 0.1 0.0 0.3 0.5 0.3 0.2 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 28.4 29.8 6.3 157.1 2.2 13.3 22.4 0.4 0.0 1.1 0.0 0.0 0.0 0.0 0.0 5.9 0.0 4.3 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 28.5 0.0 1.4 8.3 0.3 0.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 6.5 0.0 59.6 0.7 0.3 0.0 0.0 0.9 6.7 0.1 1257.1 55.0 0.0 0.7 0.0 0.2 30.6 CCDC200 "LINC00854, TMEM106A-AS1" ENSG00000236383 "Coiled-coil domain containing 200" A0A1B0GVQ3 17 43216941-43305397 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 45.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 8.8;NK-cell: 7.3" "Group enriched" "Detected in many" 5 "granulocytes: 8.8;NK-cells: 7.3" "Cell line enhanced" "Detected in many" "HeLa: 7.6;Hep G2: 6.8;HMC-1: 4.6" "Not detected" "Not detected" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (3.14e-2)" "unprognostic (1.97e-1)" "unprognostic (1.81e-3)" "unprognostic (4.29e-2)" "unprognostic (3.95e-2)" "unprognostic (7.19e-4)" "unprognostic (1.41e-3)" "unprognostic (1.73e-1)" "unprognostic (1.10e-1)" "unprognostic (1.97e-1)" "unprognostic (1.17e-1)" "unprognostic (2.10e-1)" "unprognostic (2.88e-4)" "unprognostic (2.11e-1)" "unprognostic (3.88e-2)" "unprognostic (5.95e-2)" "unprognostic (3.08e-2)" 0.9 0.7 0.7 2.1 2.3 2.2 0.6 9.7 1.3 1.2 0.0 0.6 0.6 0.7 0.6 0.9 0.8 0.9 0.7 0.4 1.6 3.7 0.7 1.2 2.5 2.6 2.0 1.2 0.6 0.0 0.6 0.8 1.6 0.9 0.1 4.5 0.9 0.0 1.7 2.4 1.0 0.2 0.2 2.7 1.0 45.2 2.3 0.1 1.7 0.0 0.5 0.7 0.6 4.3 0.8 3.2 0.6 0.9 0.1 0.1 1.4 1.0 0.0 0.2 0.0 2.9 0.8 1.7 0.8 0.5 0.4 0.9 0.0 0.0 0.0 1.0 2.4 1.1 7.6 6.8 0.5 0.9 4.6 0.0 0.3 0.0 0.0 0.4 0.0 1.5 0.3 1.0 0.0 2.8 1.5 4.0 0.2 1.2 0.4 2.5 0.8 0.2 0.0 0.2 2.0 0.1 0.6 0.9 0.5 0.5 0.4 1.7 2.6 1.1 0.7 1.0 0.5 1.2 0.4 0.4 0.6 2.0 1.1 8.8 1.0 1.1 0.6 0.8 0.3 0.9 0.4 0.4 0.3 1.7 0.4 0.4 3.1 7.3 0.3 1.7 0.4 0.4 0.7 2.3 9.7 1.3 0.4 1.6 2.6 2.0 1.6 0.2 2.3 4.3 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCL15 "HCC-2, HMRP-2B, Lkn-1, MIP-1d, MIP-5, NCC-3, SCYA15, SCYL3" ENSG00000275718 "C-C motif chemokine ligand 15" Q16663 17 35996440-36001553 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Cytokine, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 83.0;liver: 31.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 262.6;Intestinal goblet cells: 208.3;Paneth cells: 380.6;Proximal enterocytes: 461.4;Undifferentiated cells: 138.2" "Cancer enhanced" "Detected in many" "liver cancer: 11.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "Hep G2: 35.4;OE19: 28.7" HPA058608 Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 3270000 11000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" Vesicles "HPA058608: AB_2683776" "unprognostic (1.26e-1)" "unprognostic (1.23e-1)" "unprognostic (1.31e-2)" "unprognostic (1.40e-1)" "unprognostic (8.88e-2)" "unprognostic (1.50e-1)" "unprognostic (1.63e-1)" "unprognostic (2.45e-1)" "unprognostic (2.41e-2)" "unprognostic (1.96e-2)" "unprognostic (9.94e-2)" "unprognostic (1.15e-1)" "unprognostic (1.07e-2)" "prognostic favorable (3.02e-4)" 0.2 0.4 0.1 7.8 0.1 0.1 0.4 0.1 0.3 0.3 0.0 59.7 37.6 0.1 0.0 0.2 9.6 9.2 0.0 0.1 0.1 10.0 31.6 2.1 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 83.0 0.0 0.1 0.1 0.0 0.1 62.0 1.4 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.3 4.9 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 35.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.1 0.0 28.7 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.3 0.5 0.0 0.5 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.1 0.1 7.2 5.0 0.0 0.0 0.0 0.0 262.6 0.0 0.0 0.0 12.2 0.1 0.7 71.8 0.0 0.0 0.7 0.0 0.0 0.0 0.1 8.9 0.0 2.5 40.2 0.1 0.0 0.0 208.3 2.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 380.6 0.0 0.0 0.0 461.4 61.3 76.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 138.2 0.2 CD14 ENSG00000170458 "CD14 molecule" P08571 5 140631728-140633701 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 403.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 2809.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3697.0" "Group enriched" "Detected in all" 5 "granulocytes: 942.3;monocytes: 3697.0" "Cell line enhanced" "Detected in many" "A549: 10.1;CACO-2: 17.0;SiHa: 21.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001887, HPA002127, CAB033631, CAB072865, CAB072866" Enhanced Approved Vesicles "Secreted to blood" NA NA 2750000000 10000000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" Vesicles "CAB033631: AB_781932, CAB072865: AB_2665714, CAB072866: AB_2665715, HPA001887: AB_1078442, HPA002127: AB_1078440" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (3.42e-3)" "unprognostic (3.89e-2)" "unprognostic (3.29e-2)" "unprognostic (1.54e-1)" "unprognostic (4.71e-3)" "unprognostic (4.88e-2)" "unprognostic (2.16e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.80e-5)" "unprognostic (1.20e-2)" "unprognostic (6.87e-3)" "unprognostic (8.12e-2)" "unprognostic (6.92e-2)" 134.5 151.3 15.9 236.1 16.0 68.8 50.5 14.7 33.1 27.9 26.8 55.9 31.4 23.5 21.0 23.9 40.5 79.8 35.6 14.5 23.2 41.6 403.4 91.6 107.9 33.6 26.4 21.4 27.0 16.7 35.5 183.0 29.6 18.3 47.6 4.0 121.8 30.4 10.6 13.5 38.0 111.7 25.4 87.6 33.9 26.6 30.3 20.9 23.0 17.5 23.0 102.5 12.6 42.1 0.1 10.1 0.1 0.8 1.3 0.3 0.5 0.9 4.7 1.9 2.1 17.0 3.1 0.4 1.0 5.9 1.4 4.9 0.0 2.6 0.5 0.1 1.4 0.3 1.1 2.0 5.1 1.1 0.3 4.8 0.3 0.3 1.5 0.4 0.0 0.3 0.3 0.3 1.7 0.3 0.1 1.2 0.4 0.3 0.3 0.4 0.6 1.8 0.2 0.1 3.6 1.3 21.1 0.5 0.5 0.2 0.3 2.1 0.6 0.4 0.4 1.9 2.1 0.8 1.6 0.8 0.4 0.5 0.1 13.5 3697.0 21.7 6.8 677.3 8.7 12.1 3.7 3.9 440.4 1.9 5.2 3.6 942.3 3.8 95.1 25.2 3.7 3034.0 15.9 16.0 14.7 33.1 14.5 23.2 33.6 26.4 29.6 25.4 30.3 42.1 17.9 9.6 27.6 0.7 9.0 5.1 3.4 5.2 6.2 7.2 164.9 23.4 2.6 22.8 18.3 1.8 0.0 18.1 5.3 77.2 1.9 5.1 2.3 0.6 1.7 46.5 7.2 29.5 0.7 1.8 16.3 19.7 1.1 1.0 8.8 0.6 340.2 348.0 2809.2 33.7 0.9 5.9 4.1 668.4 75.9 6.1 5.0 652.8 8.8 23.4 285.3 30.0 11.3 0.5 0.4 1.8 35.3 5.3 1.8 1.7 5.0 7.0 9.8 5.1 32.9 25.8 9.7 1.5 2.0 4.4 4.3 46.1 5.5 2.1 7.4 4.9 CD163 "M130, MM130, SCARI1" ENSG00000177575 "CD163 molecule" Q86VB7 12 7470811-7503893 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Acute phase, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 240.5" "Cell type enriched" "Detected in many" 4 "Kupffer cells: 1756.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 76.1;myeloid DC: 65.2" "Group enriched" "Detected in many" 40 "dendritic cells: 65.2;monocytes: 76.1" "Cell line enhanced" "Detected in some" "GAMG: 1.8;HSkMC: 1.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB002432, HPA046404, HPA051974" Enhanced Supported "Plasma membrane" "Secreted to blood" NA NA 903000000 1600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB002432: AB_563510, HPA046404: AB_2679655, HPA051974: AB_2681678" "unprognostic (1.13e-1)" "unprognostic (2.13e-1)" "unprognostic (5.02e-3)" "unprognostic (2.72e-1)" "unprognostic (6.17e-3)" "unprognostic (2.09e-1)" "unprognostic (1.02e-1)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.04e-1)" "unprognostic (6.50e-2)" "unprognostic (1.84e-2)" "unprognostic (8.77e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (1.20e-2)" 171.8 85.6 6.1 152.5 7.0 17.6 50.8 5.2 18.4 25.6 21.5 48.7 12.4 27.3 3.6 16.4 68.1 43.5 52.7 4.9 7.9 27.3 89.7 131.7 54.4 15.8 10.9 23.1 21.4 8.8 11.4 109.4 18.0 15.5 21.6 4.3 25.9 7.2 11.4 15.3 52.9 130.4 7.2 240.5 35.6 9.7 55.9 18.7 17.2 17.6 7.2 68.5 16.3 10.3 0.0 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 1.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 76.1 0.5 0.1 6.4 0.0 0.0 0.0 0.1 65.2 0.0 0.0 0.0 1.7 0.0 0.0 1.0 0.1 20.1 6.1 7.0 5.2 18.4 4.9 7.9 15.8 10.9 18.0 7.2 55.9 10.3 2.7 3.2 8.3 0.0 3.8 1.5 0.2 0.0 0.0 0.1 0.1 0.3 4.6 7.2 5.0 0.0 2.1 1.5 0.5 0.0 0.0 0.0 4.3 0.0 0.1 13.9 0.0 3.6 0.4 0.0 1.9 3.0 0.5 0.0 5.1 0.1 17.9 13.9 269.9 0.0 0.5 0.0 0.0 1756.1 30.9 6.4 5.0 387.9 0.0 2.8 41.1 0.9 1.0 0.0 0.0 0.0 0.0 1.2 1.0 0.1 0.0 0.2 1.6 0.2 118.3 1.7 4.0 3.9 2.6 0.5 1.0 3.0 1.3 0.0 0.0 0.1 CD209 "CDSIGN, CLEC4L, DC-SIGN, DC-SIGN1" ENSG00000090659 "CD209 molecule" Q9NNX6 19 7739993-7747564 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Endocytosis, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 34.2;placenta: 22.8" "Group enriched" "Detected in some" 4 "Kupffer cells: 15.6;Langerhans cells: 14.7;Macrophages: 12.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "classical monocyte: 1.4;intermediate monocyte: 1.4;myeloid DC: 1.2" "Group enriched" "Detected in many" 4 "dendritic cells: 1.2;monocytes: 1.4" "Cell line enriched" "Detected in single" 14 "THP-1: 3.3" "CAB032436, CAB033831" Supported "Intracellular and membrane" NA NA 3100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB032436: AB_639039, CAB033831: AB_1121347" "unprognostic (2.76e-1)" "unprognostic (1.15e-2)" "unprognostic (5.36e-3)" "unprognostic (1.25e-1)" "unprognostic (4.43e-2)" "unprognostic (1.40e-1)" "unprognostic (5.45e-2)" "unprognostic (3.83e-2)" "unprognostic (2.10e-2)" "unprognostic (1.24e-1)" "unprognostic (9.65e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.15e-5)" "unprognostic (1.70e-1)" "unprognostic (5.51e-2)" "unprognostic (6.17e-2)" "unprognostic (1.09e-1)" 34.2 3.9 0.3 8.6 0.6 0.4 4.4 1.3 3.0 4.0 5.7 10.5 14.3 1.4 1.0 4.8 2.5 8.6 4.5 0.3 0.7 2.1 3.3 4.9 18.1 1.0 0.6 1.0 1.0 0.8 0.7 22.8 0.8 0.8 13.9 0.1 2.1 1.9 0.9 1.4 19.3 10.6 0.9 2.4 4.1 2.1 0.6 5.4 1.4 1.5 2.3 20.2 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.0 1.4 0.0 0.1 0.0 0.0 1.2 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.4 0.3 0.6 1.3 3.0 0.3 0.7 1.0 0.6 0.8 0.9 0.6 0.8 0.3 0.0 0.0 0.0 0.4 0.5 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 1.3 0.0 0.0 0.1 3.5 0.0 0.0 0.0 0.0 15.6 14.7 0.3 0.0 12.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.1 0.9 0.1 0.1 0.0 0.0 0.1 CDH9 ENSG00000113100 "Cadherin 9" Q9ULB4 5 26880597-27121150 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.8;kidney: 5.7" "Group enriched" "Detected in some" 33 "Excitatory neurons: 307.2;Inhibitory neurons: 459.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "amygdala: 6.8;basal ganglia: 4.3;cerebral cortex: 6.4;hippocampal formation: 5.8" "Immune cell enhanced" "Detected in some" "neutrophil: 4.9" "Group enriched" "Detected in many" 5 "B-cells: 2.3;granulocytes: 4.9" "Cell line enhanced" "Detected in some" "K-562: 7.3;NTERA-2: 10.1;U-698: 4.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA007167 Approved Approved "Golgi apparatus" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA007167: AB_1078489" "unprognostic (1.49e-1)" "unprognostic (2.27e-4)" 0.3 0.2 6.8 0.6 4.3 1.9 0.3 0.0 6.4 0.0 0.0 0.4 0.5 0.5 0.6 0.4 0.2 0.4 0.1 5.8 0.0 5.7 0.1 0.3 1.0 0.0 0.0 0.3 0.6 0.1 0.0 0.4 0.0 0.5 0.6 1.3 0.2 0.1 0.1 1.0 0.8 0.4 0.0 0.4 0.5 2.2 0.0 0.2 1.0 0.1 1.0 0.3 0.0 0.9 1.9 0.7 0.4 0.6 0.2 0.0 1.2 0.0 0.3 0.1 0.2 0.0 0.7 1.0 0.1 0.1 0.1 0.2 0.1 0.2 0.0 0.1 0.2 0.4 0.6 2.2 0.0 0.0 1.2 0.2 0.3 0.0 0.0 0.0 0.1 0.6 7.3 1.8 0.0 1.3 0.6 0.4 10.1 0.2 0.4 0.2 0.2 0.3 0.3 0.4 2.2 0.2 0.0 0.3 0.3 1.8 0.3 0.7 1.3 0.1 0.7 0.6 0.2 2.0 0.8 4.6 0.6 0.8 0.6 1.2 0.1 0.2 0.1 0.4 0.3 2.3 0.1 0.1 0.1 1.6 0.1 0.3 4.9 0.0 0.7 0.5 0.5 0.6 6.8 4.3 0.0 6.4 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 10.4 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 307.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 459.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 11.6 5.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CDHR2 "FLJ20124, FLJ20383, PC-LKC, PCDH24, PCLKC" ENSG00000074276 "Cadherin related family member 2" Q9BYE9 5 176542511-176595974 "Plasma proteins, Predicted membrane proteins" "Cell adhesion, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 275.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 167.0;Early spermatids: 182.4;Late spermatids: 680.0;Paneth cells: 215.0;Proximal enterocytes: 611.4" "Group enriched" "Detected in many" 14 "colorectal cancer: 9.1;liver cancer: 5.7;pancreatic cancer: 11.7;renal cancer: 8.6;stomach cancer: 9.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 17 "Hep G2: 22.2" "Region enriched" "Detected in single" 6 "hypothalamus: 2.1" "Low region specificity" "Detected in all" "HPA012569, HPA017053" Enhanced NA NA 8800000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "HPA012569: AB_1845298, HPA017053: AB_1845297" "unprognostic (1.34e-2)" "unprognostic (8.90e-4)" "unprognostic (3.82e-2)" "unprognostic (8.51e-2)" "unprognostic (5.10e-4)" "unprognostic (4.24e-3)" "unprognostic (6.66e-2)" "unprognostic (2.06e-3)" "unprognostic (1.54e-1)" "unprognostic (1.99e-1)" "unprognostic (7.66e-3)" "unprognostic (1.75e-1)" "prognostic favorable (9.29e-4)" "unprognostic (6.58e-2)" "unprognostic (3.55e-1)" "unprognostic (2.30e-2)" "unprognostic (1.42e-1)" 0.0 0.1 0.8 4.5 0.4 0.2 0.0 0.1 0.7 0.0 0.0 23.2 275.8 0.1 0.0 0.1 0.6 5.0 0.0 1.2 0.4 10.1 30.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 12.6 0.3 0.0 0.0 0.0 0.1 238.3 1.1 0.0 0.1 12.4 4.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.2 0.2 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.1 22.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.2 0.5 0.0 0.2 0.0 0.1 0.0 1.3 0.0 0.0 0.3 1.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.1 0.7 1.2 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 2.3 1.2 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.6 8.6 0.0 1.8 0.0 0.0 0.3 167.0 0.0 4.0 182.4 3.2 0.1 0.2 33.6 0.0 3.9 1.0 0.0 0.0 55.0 0.1 0.0 0.0 0.0 15.3 0.0 0.0 4.2 42.7 0.0 0.6 0.0 680.0 1.5 0.5 0.0 1.0 0.0 1.6 0.0 1.5 0.5 15.3 215.0 2.2 0.1 0.0 611.4 13.7 0.7 0.3 0.0 0.0 0.1 3.8 2.0 0.0 0.0 0.1 0.7 3.5 19.8 0.0 CDHR5 "FLJ20219, MU-PCDH, MUCDHL, MUPCDH" ENSG00000099834 "Cadherin related family member 5" Q9HBB8 11 616577-626078 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 296.8;liver: 129.8" "Group enriched" "Detected in some" 7 "Distal enterocytes: 811.5;Paneth cells: 732.4;Proximal enterocytes: 2545.8" "Cancer enhanced" "Detected in many" "liver cancer: 61.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "OE19: 13.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009081, HPA009173, CAB025004" Enhanced "Intracellular and membrane" NA NA 190000000 "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "CAB025004: , HPA009081: AB_1079428, HPA009173: AB_1079429" "unprognostic (7.65e-2)" "unprognostic (1.42e-1)" "unprognostic (9.85e-2)" "unprognostic (1.21e-1)" "unprognostic (1.05e-1)" "unprognostic (5.56e-3)" "unprognostic (4.89e-2)" "unprognostic (3.85e-2)" "unprognostic (5.75e-2)" "unprognostic (6.36e-2)" "unprognostic (7.95e-2)" "unprognostic (5.07e-2)" "unprognostic (5.01e-2)" "unprognostic (3.90e-1)" "unprognostic (8.85e-2)" "unprognostic (2.29e-1)" "unprognostic (2.14e-2)" 0.1 0.9 0.2 4.0 0.6 0.1 0.4 0.5 0.4 0.1 2.2 102.2 241.2 0.2 0.0 0.3 0.3 3.9 0.0 0.2 0.0 44.9 129.8 0.2 0.2 0.2 0.1 0.2 1.8 0.0 0.6 0.0 0.3 0.1 51.9 0.1 0.0 0.1 0.1 0.1 296.8 2.7 0.0 0.1 4.3 0.3 0.3 0.0 0.1 0.0 0.0 0.1 0.1 0.8 0.0 0.3 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 3.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.3 13.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.5 0.4 0.2 0.0 0.2 0.1 0.3 0.0 0.3 0.8 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 11.5 0.0 1.8 0.0 0.0 1.4 811.5 13.7 0.3 2.8 0.1 0.2 0.1 92.8 0.0 0.0 1.3 0.0 0.0 33.6 0.4 13.4 0.0 4.6 126.1 0.1 0.0 0.1 193.2 0.0 4.3 0.0 18.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 732.4 0.0 0.0 0.0 2545.8 107.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 154.6 0.0 CEACAM1 "BGP, BGP1, CD66a" ENSG00000079385 "CEA cell adhesion molecule 1" P13688 19 42507304-42561234 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 246.3" "Group enriched" "Detected in many" 5 "Basal prostatic cells: 335.2;Distal enterocytes: 731.7;Paneth cells: 585.4;Prostatic glandular cells: 244.9;Urothelial cells: 618.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 43.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "eosinophil: 43.6;neutrophil: 26.3" "Lineage enriched" "Detected in many" 13 "granulocytes: 43.6" "Group enriched" "Detected in many" 5 "CAPAN-2: 30.6;Hep G2: 101.0;OE19: 80.9;RT4: 59.2;SK-MEL-30: 67.4" "CAB002146, HPA011041" Enhanced "Intracellular and membrane" NA NA 130000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB002146: AB_563614, HPA011041: AB_1078481" "unprognostic (7.13e-3)" "unprognostic (2.15e-1)" "unprognostic (2.67e-2)" "prognostic favorable (6.32e-7)" "unprognostic (3.04e-1)" "unprognostic (1.80e-3)" "unprognostic (1.21e-1)" "unprognostic (4.45e-2)" "unprognostic (4.43e-1)" "unprognostic (5.46e-3)" "unprognostic (4.87e-2)" "unprognostic (4.03e-1)" "unprognostic (1.92e-2)" "unprognostic (1.88e-1)" "unprognostic (1.06e-1)" "unprognostic (7.55e-2)" "unprognostic (5.52e-3)" 11.9 10.6 1.3 31.1 0.8 74.5 13.3 3.2 1.8 16.4 0.0 246.3 53.3 11.1 3.9 64.9 6.0 7.4 4.0 1.9 0.0 31.9 60.5 6.8 4.3 0.4 0.1 1.1 2.4 1.7 3.8 33.1 0.5 20.2 141.2 0.6 58.9 10.3 2.7 3.3 51.0 13.1 0.0 7.9 19.9 3.7 0.2 2.3 3.1 3.1 21.5 37.0 29.2 0.0 0.6 5.6 0.3 0.3 0.0 0.0 14.4 0.0 0.2 1.0 0.5 2.3 30.6 1.7 12.2 0.0 3.2 0.8 0.0 7.9 0.4 0.1 0.5 0.3 0.2 101.0 1.7 0.2 13.3 0.0 0.1 0.1 0.1 0.0 0.7 1.4 0.0 5.0 0.0 3.2 0.3 0.2 0.9 80.9 1.7 2.6 0.0 1.3 0.6 59.2 0.5 0.2 0.0 0.2 67.4 7.3 0.3 0.0 2.1 0.3 1.2 1.4 0.5 1.8 0.0 3.7 0.2 0.4 1.0 0.8 0.0 43.6 0.1 1.7 0.3 3.3 0.9 0.4 0.2 0.8 0.6 0.2 26.3 0.1 3.3 0.1 2.7 0.6 1.3 0.8 3.2 1.8 1.9 0.0 0.4 0.1 0.5 0.0 0.2 0.0 16.7 6.4 8.2 1.0 6.0 1.3 335.2 10.4 2.8 6.0 16.3 12.7 1.8 7.2 14.7 0.0 4.2 2.0 0.7 731.7 0.0 21.3 3.5 5.0 5.2 22.3 17.3 0.4 1.7 16.1 9.4 2.9 12.8 28.7 8.9 4.6 41.4 37.7 1.4 5.0 1.4 46.1 4.1 5.9 3.1 0.2 0.0 2.6 7.2 0.0 0.9 1.3 2.1 0.5 0.6 58.7 585.4 0.7 0.2 244.9 97.5 11.1 3.9 6.4 0.0 2.7 3.1 4.3 3.9 9.2 1.0 0.7 5.5 2.2 33.2 618.9 CES3 "ES31, FLJ21736" ENSG00000172828 "Carboxylesterase 3" Q6UWW8 16 66961245-66975149 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.2;liver: 52.5;skeletal muscle: 24.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 120.1;Granulosa cells: 58.5;Hepatocytes: 53.4;Intestinal goblet cells: 32.0;Paneth cells: 67.0;Proximal enterocytes: 66.0;Undifferentiated cells: 44.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 7.4;Daudi: 8.5;JURKAT: 13.5;U-937: 7.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041008, HPA041307" Approved Approved "Nuclear membrane,Endoplasmic reticulum" "Intracellular and membrane" NA NA 1200000 "Cluster 52: Eosinophils - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear membrane, Endoplasmic reticulum" "HPA041008: AB_2677247, HPA041307: AB_2677400" "unprognostic (3.91e-3)" "unprognostic (1.22e-1)" "unprognostic (1.94e-2)" "unprognostic (8.99e-3)" "unprognostic (9.32e-2)" "unprognostic (7.84e-4)" "prognostic favorable (7.26e-5)" "unprognostic (5.67e-3)" "unprognostic (1.52e-1)" "unprognostic (2.17e-1)" "unprognostic (6.43e-2)" "unprognostic (1.84e-2)" "unprognostic (1.19e-2)" "unprognostic (2.18e-2)" "unprognostic (2.75e-1)" "unprognostic (3.31e-2)" "unprognostic (7.41e-2)" 0.8 0.5 3.1 3.2 2.7 0.9 2.3 2.5 2.9 1.3 1.3 38.2 30.0 0.7 0.2 4.2 2.9 0.9 0.7 3.8 2.0 12.2 52.5 0.7 0.3 3.3 2.7 0.6 4.1 1.0 1.9 0.6 3.5 0.5 31.3 0.6 12.0 0.3 24.7 1.2 23.7 1.2 1.4 0.4 7.7 1.1 2.2 0.2 0.4 1.5 0.2 0.1 0.8 2.2 0.4 3.1 0.3 7.4 0.2 0.2 1.2 0.2 0.2 0.3 0.5 0.5 3.8 8.5 2.4 0.0 0.2 0.6 1.1 0.5 0.1 1.5 5.5 4.3 1.3 2.6 0.0 0.9 0.7 0.3 0.9 0.8 0.1 0.2 0.0 13.5 2.8 1.7 0.3 1.1 1.4 1.4 1.5 2.6 0.4 1.3 0.7 1.3 0.1 0.4 0.4 0.8 0.2 5.8 0.2 0.6 5.0 6.5 0.3 0.4 2.4 0.7 0.2 0.9 3.6 1.3 0.3 7.2 0.2 0.2 0.1 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.1 0.0 3.1 2.7 2.5 2.9 3.8 2.0 3.3 2.7 3.5 1.4 2.2 2.2 0.1 3.2 6.7 0.7 0.4 0.5 0.0 1.3 1.2 0.2 9.1 5.7 1.4 2.8 0.9 0.0 0.0 0.0 0.0 120.1 0.0 0.2 0.5 3.2 0.3 0.2 19.7 0.0 1.8 0.9 0.0 0.2 11.7 4.4 1.3 58.5 0.4 53.4 0.3 0.0 2.9 32.0 0.0 3.2 0.9 5.4 0.0 0.9 0.0 0.0 0.0 0.4 0.0 1.5 0.1 1.0 67.0 1.2 0.1 0.1 66.0 9.9 4.8 0.2 0.0 0.6 0.2 2.3 2.9 1.1 0.3 0.0 0.4 0.1 44.3 0.2 CHDH ENSG00000016391 "Choline dehydrogenase" Q8NE62 3 53812335-53846419 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 37.6;liver: 35.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 52.9;Hepatocytes: 51.8;Proximal enterocytes: 70.1;Proximal tubular cells: 87.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "basophil: 3.1;T-reg: 1.3" "Group enriched" "Detected in many" 17 "granulocytes: 3.1;T-cells: 1.3" "Cell line enhanced" "Detected in many" "CACO-2: 11.4;Hep G2: 35.8;OE19: 25.3;T-47d: 11.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA036633, HPA058130" Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036633: AB_10670841, HPA058130: AB_2683615" "unprognostic (3.40e-3)" "unprognostic (1.17e-2)" "unprognostic (2.26e-3)" "unprognostic (7.17e-3)" "unprognostic (9.15e-2)" "unprognostic (1.17e-3)" "unprognostic (1.10e-1)" "unprognostic (1.97e-2)" "unprognostic (2.75e-1)" "unprognostic (4.35e-3)" "unprognostic (4.57e-2)" "unprognostic (5.12e-2)" "prognostic favorable (1.88e-8)" "unprognostic (3.37e-2)" "unprognostic (2.42e-1)" "unprognostic (8.26e-2)" "unprognostic (2.29e-2)" 0.6 2.8 13.6 1.8 14.3 0.6 7.3 12.5 11.4 3.7 16.5 8.9 8.4 2.7 1.4 0.9 2.6 2.7 2.4 11.3 10.9 37.6 35.8 2.4 1.0 14.5 13.9 1.3 16.4 8.3 7.8 0.4 10.1 5.8 9.2 1.5 15.0 1.0 3.9 2.4 14.7 0.9 10.3 0.5 8.0 6.9 15.9 0.2 2.6 1.2 1.2 0.4 0.9 12.0 0.4 4.6 1.2 0.1 0.0 0.0 5.2 0.3 0.5 0.0 0.0 11.4 0.8 0.4 0.8 0.8 0.1 0.0 7.4 0.0 0.0 0.0 4.0 0.0 1.7 35.8 0.0 0.1 0.7 0.1 0.0 0.0 0.0 0.6 0.0 0.0 5.7 0.7 0.0 6.9 0.0 0.1 7.2 25.3 0.8 0.0 1.8 8.2 5.1 4.0 3.0 4.0 1.8 0.1 0.0 0.9 11.2 0.1 0.0 0.0 0.8 0.2 1.0 1.0 1.6 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 13.6 14.3 12.5 11.4 11.3 10.9 14.5 13.9 10.1 10.3 15.9 12.0 0.6 3.2 6.8 19.6 1.3 6.6 5.6 1.1 1.2 23.8 23.5 19.8 11.3 52.9 5.9 11.0 14.6 3.7 0.4 16.6 7.9 19.4 28.9 3.2 11.0 1.4 47.9 0.0 2.4 13.8 2.3 2.3 21.4 9.4 7.0 2.2 1.4 51.8 0.3 1.7 3.5 38.9 0.0 1.9 2.5 46.2 5.9 2.6 3.6 1.0 0.1 18.8 0.0 27.2 5.2 8.0 15.1 15.4 5.3 19.8 70.1 87.8 3.8 13.4 0.0 1.0 3.4 15.1 2.3 0.7 5.3 0.8 2.4 2.0 45.4 2.2 CHP2 ENSG00000166869 "Calcineurin like EF-hand protein 2" O43745 16 23755026-23758935 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 16 "intestine: 305.0;skin 1: 149.7" "Group enriched" "Detected in some" 5 "Distal enterocytes: 345.0;Paneth cells: 274.0;Proximal enterocytes: 654.2;Undifferentiated cells: 205.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 10.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 7.3;hTERT-RPE1: 10.2;NB-4: 8.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055198, CAB072806" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Nucleoli, Cytosol" "CAB072806: , HPA055198: " "unprognostic (4.82e-1)" "unprognostic (3.40e-1)" "unprognostic (4.93e-2)" "unprognostic (1.01e-2)" "unprognostic (8.85e-2)" "unprognostic (3.54e-1)" "unprognostic (4.54e-2)" "unprognostic (1.47e-1)" "unprognostic (1.38e-1)" "unprognostic (5.31e-2)" "unprognostic (4.70e-2)" "unprognostic (1.44e-5)" "unprognostic (2.21e-1)" "unprognostic (5.97e-2)" "unprognostic (7.84e-2)" "unprognostic (9.01e-2)" 0.4 0.2 1.1 3.8 1.1 2.2 4.3 3.6 1.3 14.0 0.0 146.7 305.0 0.9 1.1 0.6 0.9 0.4 0.4 0.7 1.6 4.1 0.7 0.6 0.8 0.5 0.1 0.4 0.5 0.1 0.0 1.4 0.9 3.8 147.4 1.3 0.8 4.5 1.2 149.7 250.5 6.5 0.1 0.3 1.1 7.3 0.9 0.5 0.6 0.2 0.4 9.0 4.2 2.9 1.0 2.2 0.5 0.6 1.2 1.3 1.2 2.9 1.1 0.3 1.0 0.5 2.3 0.4 0.9 2.5 1.2 1.4 0.4 2.9 0.6 0.7 0.2 0.5 4.1 1.6 1.7 0.3 0.7 0.9 0.8 2.5 7.3 10.2 1.1 0.3 1.2 1.0 1.2 0.1 0.1 8.7 0.3 0.5 2.1 0.2 0.1 1.4 1.1 0.7 0.6 0.7 0.8 0.2 0.0 0.6 0.2 0.2 1.3 0.5 0.6 0.7 0.1 0.4 0.1 0.2 0.0 0.5 0.5 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.0 0.1 0.1 0.0 0.0 1.1 1.1 3.6 1.3 0.7 1.6 0.5 0.1 0.9 0.1 0.9 2.9 0.0 0.0 0.0 0.0 0.0 10.3 8.7 6.1 0.0 0.0 0.0 0.1 0.1 0.0 24.4 1.8 0.0 0.9 0.0 345.0 0.0 0.0 0.6 1.3 0.5 0.2 9.1 0.0 0.0 0.0 4.1 0.2 0.0 3.6 4.5 0.7 0.0 0.0 0.1 0.0 0.0 70.0 12.2 0.0 1.6 0.5 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 274.0 0.0 0.0 2.5 654.2 12.9 4.4 0.0 0.0 0.0 0.3 0.0 0.2 0.0 67.5 0.7 0.2 0.2 205.4 29.9 CHRNA4 "BFNC, EBN, EBN1" ENSG00000101204 "Cholinergic receptor nicotinic alpha 4 subunit" P43681 20 63343223-63378401 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 28.8;liver: 58.0" "Group enriched" "Detected in some" 4 "Hepatocytes: 42.0;Horizontal cells: 139.7" "Cancer enhanced" "Detected in some" "liver cancer: 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "U-2 OS: 2.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "midbrain: 21.8;pons: 20.5;thalamus: 33.5" CAB034064 Uncertain NA NA "Cluster 15: Liver - Metabolism" "Cluster 9: U-2 OS - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "CAB034064: AB_2080535" "unprognostic (3.40e-1)" "unprognostic (1.71e-1)" "unprognostic (2.87e-2)" "unprognostic (3.98e-1)" "unprognostic (8.03e-2)" "unprognostic (1.75e-1)" "unprognostic (1.22e-1)" "unprognostic (1.74e-1)" "unprognostic (2.10e-3)" "unprognostic (5.72e-4)" "unprognostic (9.02e-3)" "unprognostic (9.79e-4)" "unprognostic (6.77e-2)" "unprognostic (1.08e-1)" "unprognostic (3.81e-2)" 0.0 0.2 6.7 0.0 6.5 0.0 0.0 0.6 6.2 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.7 8.7 3.4 58.0 0.0 0.0 5.7 15.7 0.1 0.0 12.7 0.8 0.0 6.2 0.2 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.5 0.0 1.6 28.8 0.0 0.5 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 6.5 0.6 6.2 6.7 8.7 5.7 15.7 6.2 0.5 28.8 4.9 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 22.4 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 4.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 42.0 0.0 139.7 8.8 0.0 0.0 1.0 0.0 1.1 0.0 0.0 0.0 1.0 0.0 0.9 0.0 7.5 2.1 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 2.7 0.0 1.7 0.1 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 CLDN16 "HOMG3, PCLN1" ENSG00000113946 "Claudin 16" Q9Y5I7 3 190322541-190412138 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Disease variant, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "kidney: 63.6" "Cell type enriched" "Detected in some" 8 "Distal tubular cells: 187.9" "Group enriched" "Detected in many" 15 "ovarian cancer: 39.8;thyroid cancer: 29.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 153 "EFO-21: 691.6;RPTEC TERT1: 233.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA056020 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA056020: AB_2683011" "unprognostic (5.01e-2)" "unprognostic (7.83e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.99e-5)" "unprognostic (6.06e-4)" "unprognostic (1.30e-1)" "unprognostic (2.07e-1)" "unprognostic (2.39e-2)" "unprognostic (3.31e-1)" "unprognostic (4.20e-1)" "unprognostic (2.76e-3)" "unprognostic (3.70e-1)" "unprognostic (1.96e-1)" "unprognostic (5.76e-2)" "unprognostic (8.08e-2)" "unprognostic (1.62e-2)" "unprognostic (1.15e-1)" 0.1 0.7 0.3 0.2 0.4 0.0 0.2 0.0 0.5 0.1 1.5 0.0 0.0 0.3 0.6 0.5 2.9 0.7 0.0 0.2 0.2 63.6 2.2 0.4 1.5 0.2 0.1 0.0 0.2 0.0 0.0 0.2 0.2 0.1 0.0 0.1 0.4 0.9 0.0 3.2 0.0 0.4 0.1 0.1 0.1 0.1 0.3 0.3 9.7 0.0 1.0 0.3 0.2 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 691.6 0.0 0.3 0.7 0.0 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.8 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 233.2 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.3 0.0 0.0 2.2 0.0 0.3 1.4 1.2 3.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.5 0.2 0.2 0.2 0.1 0.2 0.1 0.3 0.6 0.1 0.0 0.0 0.3 0.0 7.0 5.8 2.6 0.6 0.3 0.8 0.3 0.4 4.3 1.6 9.2 0.0 0.4 0.0 0.0 187.9 3.4 2.0 3.0 0.1 0.2 0.0 0.0 5.0 0.4 0.2 0.9 0.0 0.5 1.3 0.3 0.0 1.6 0.1 3.3 3.6 0.0 0.0 0.3 1.2 0.2 0.0 0.4 5.4 2.8 0.0 0.2 0.0 4.0 0.1 0.5 0.0 0.4 0.0 6.7 0.0 0.9 22.1 0.2 0.0 0.8 0.6 0.3 0.3 0.9 12.6 6.2 0.2 0.2 0.0 3.1 CLEC18A MRCL ENSG00000157322 "C-type lectin domain family 18 member A" A5D8T8 16 69950705-69964452 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "kidney: 23.9" "Cell type enriched" "Detected in some" 23 "Proximal tubular cells: 78.0" "Cancer enriched" "Detected in single" 7 "renal cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA048976 Uncertain "Secreted to blood" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA048976: AB_2680582" "unprognostic (1.68e-1)" "unprognostic (3.06e-2)" "unprognostic (1.19e-2)" "unprognostic (1.48e-1)" "unprognostic (3.14e-2)" "unprognostic (4.62e-2)" "unprognostic (1.36e-1)" "unprognostic (4.14e-2)" "unprognostic (1.04e-1)" "unprognostic (4.40e-2)" "unprognostic (6.77e-4)" "unprognostic (6.73e-2)" "unprognostic (4.58e-2)" "unprognostic (2.06e-1)" "unprognostic (9.03e-4)" "unprognostic (1.52e-1)" "unprognostic (2.53e-2)" 0.2 0.9 0.1 0.0 0.2 0.3 0.3 0.6 0.5 0.3 2.8 0.4 0.0 0.1 0.0 0.1 0.3 0.1 0.1 0.2 0.2 23.9 0.2 0.4 0.1 0.2 0.2 0.2 0.4 0.1 0.4 0.0 0.4 0.3 0.1 0.1 0.6 0.0 0.2 0.3 0.7 0.0 0.2 1.2 0.5 3.2 0.2 0.3 0.4 0.1 0.1 0.3 0.1 0.3 0.0 0.1 0.7 0.0 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.2 0.4 0.0 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.4 0.0 0.2 0.0 0.0 0.1 0.1 0.4 0.0 0.1 0.4 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.6 0.5 0.2 0.2 0.2 0.2 0.4 0.2 0.2 0.3 0.3 0.0 1.1 0.0 0.9 0.1 0.0 0.2 0.0 1.6 0.3 0.4 0.5 2.8 0.4 0.0 2.1 0.1 0.3 3.3 1.9 0.3 0.4 0.4 0.1 0.4 0.0 0.0 0.3 0.2 0.1 0.3 2.0 0.5 0.0 0.6 2.5 0.4 0.4 3.3 0.4 1.0 0.0 0.6 0.3 0.8 0.3 1.1 0.0 0.0 0.9 0.9 1.0 0.0 0.0 0.5 0.4 0.0 0.2 0.2 1.5 78.0 0.7 1.3 0.0 0.7 1.3 0.5 0.2 0.0 0.0 0.3 0.6 0.6 1.3 0.2 CLEC18B MRCL2 ENSG00000140839 "C-type lectin domain family 18 member B" Q6UXF7 16 74408270-74421953 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 33.4;testis: 11.8" "Cell type enriched" "Detected in some" 14 "Proximal tubular cells: 26.8" "Cancer enhanced" "Detected in some" "glioma: 2.7;renal cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.1;JURKAT: 1.6;K-562: 3.1;U-266/70: 1.1" HPA048976 Uncertain "Secreted to blood" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA048976: AB_2680582" "unprognostic (5.69e-2)" "unprognostic (1.46e-1)" "unprognostic (5.30e-3)" "unprognostic (9.37e-2)" "prognostic unfavorable (2.07e-4)" "unprognostic (7.15e-2)" "unprognostic (7.51e-2)" "unprognostic (4.49e-3)" "unprognostic (2.17e-1)" "unprognostic (2.28e-1)" "unprognostic (9.91e-2)" "unprognostic (3.58e-2)" "unprognostic (1.42e-2)" "unprognostic (2.31e-2)" "unprognostic (5.87e-2)" "unprognostic (5.43e-2)" "unprognostic (4.27e-2)" 0.1 1.9 3.4 0.4 3.7 0.1 0.2 4.5 4.9 0.5 2.6 0.2 0.4 0.1 0.6 2.7 0.3 0.3 0.2 3.8 3.8 33.4 0.6 0.2 0.1 3.7 3.6 0.2 0.6 0.0 0.8 0.1 4.0 0.5 0.1 2.3 0.6 0.0 0.2 0.2 0.3 0.1 3.6 0.6 0.3 11.8 3.3 0.2 0.6 0.0 0.0 0.1 1.7 4.4 0.0 0.6 1.1 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.2 0.2 0.4 0.4 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.0 0.1 0.6 0.1 0.0 0.0 0.2 0.0 1.6 3.1 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.3 0.1 0.0 0.6 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.3 1.1 0.7 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 3.7 4.5 4.9 3.8 3.8 3.7 3.6 4.0 3.6 3.3 4.4 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.3 0.0 0.4 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 1.5 1.9 0.1 0.1 0.1 0.1 0.1 1.2 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.4 0.4 0.0 0.0 0.0 1.6 0.3 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.6 0.5 0.1 0.0 0.0 0.0 0.4 26.8 0.0 1.4 0.0 0.0 0.2 0.5 0.2 0.0 0.1 0.0 0.1 0.0 0.3 0.0 CLEC18C "MGC34761, MRCL3" ENSG00000157335 "C-type lectin domain family 18 member C" Q8NCF0 16 70173322-70187361 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 17.8" "Cell type enriched" "Detected in single" 46 "Proximal tubular cells: 23.3" "Cancer enriched" "Detected in single" 9 "renal cancer: 1.4" "Region enhanced" "Detected in single" "cerebellum: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA048976 Uncertain "Secreted to blood" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA048976: AB_2680582" "unprognostic (3.90e-1)" "unprognostic (3.03e-1)" "unprognostic (1.20e-4)" "unprognostic (5.55e-2)" "unprognostic (5.72e-3)" "unprognostic (2.92e-1)" "unprognostic (7.64e-2)" "unprognostic (3.79e-2)" "unprognostic (3.61e-3)" "unprognostic (6.98e-2)" 0.0 0.1 0.1 0.0 0.3 0.0 0.0 1.0 0.5 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 17.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.0 0.5 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 CLIC5 DFNB102 ENSG00000112782 "Chloride intracellular channel 5" Q9NZA1 6 45880827-46080348 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Hearing, Ion transport, Sensory transduction, Transport, Vision" "Chloride channel, Ion channel, Voltage-gated channel" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 102.7;skeletal muscle: 289.7;tongue: 98.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 509.6;Cardiomyocytes: 285.7;Distal enterocytes: 164.2;Late spermatids: 93.8;Proximal enterocytes: 126.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 11.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 5.1" "Lineage enriched" "Detected in single" 17 "T-cells: 5.1" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.5;EFO-21: 9.2;HDLM-2: 4.7;REH: 11.9;U-266/70: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074371 Supported "Nuclear speckles,Plasma membrane" NA NA 400000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Nuclear speckles" "HPA074371: " "unprognostic (4.95e-2)" "unprognostic (1.59e-2)" "unprognostic (8.84e-2)" "unprognostic (5.05e-2)" "unprognostic (2.44e-1)" "unprognostic (6.73e-2)" "unprognostic (3.37e-1)" "unprognostic (1.26e-1)" "unprognostic (1.79e-1)" "unprognostic (6.46e-2)" "unprognostic (5.50e-2)" "unprognostic (3.65e-1)" "unprognostic (6.77e-3)" "unprognostic (1.22e-1)" "unprognostic (1.99e-1)" "unprognostic (8.26e-2)" "unprognostic (1.01e-1)" 18.9 1.5 3.2 4.3 4.4 0.2 6.5 1.5 2.9 19.0 0.5 28.6 20.9 2.1 0.9 2.9 4.5 3.0 102.7 2.1 5.0 54.7 0.3 70.8 1.7 2.1 3.8 0.5 1.1 1.7 3.0 16.5 2.2 2.6 25.8 16.9 2.7 1.4 289.7 1.2 36.6 2.3 1.8 44.5 1.6 1.4 5.5 1.0 7.3 98.3 1.9 2.0 2.6 1.9 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 13.5 0.0 9.2 0.0 0.0 0.3 0.0 0.1 0.0 4.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.1 0.4 1.6 0.0 11.9 0.3 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.4 0.1 0.0 12.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 1.5 0.0 5.1 0.1 2.0 1.3 0.0 0.0 0.3 0.2 0.0 0.3 0.0 0.0 1.0 0.5 3.2 4.4 1.5 2.9 2.1 5.0 2.1 3.8 2.2 1.8 5.5 1.9 59.6 509.6 30.0 4.6 1.4 0.1 0.1 0.0 1.2 0.3 0.5 0.4 285.7 5.7 26.9 14.7 0.0 0.2 0.7 164.2 0.0 1.7 52.9 4.6 0.5 29.8 13.1 0.4 8.6 0.2 0.1 7.9 0.5 5.7 1.3 0.0 0.7 0.0 0.0 0.0 5.4 23.5 0.0 0.0 0.0 93.8 0.9 0.7 0.0 34.7 0.6 53.8 0.0 0.5 2.9 2.9 51.1 0.7 3.4 3.2 126.0 2.9 11.4 1.8 0.0 6.1 4.3 1.0 0.1 0.1 0.1 2.2 5.8 0.1 13.5 4.3 CLRN3 "MGC32871, TMEM12, USH3AL1" ENSG00000180745 "Clarin 3" Q8NCR9 10 127877841-127892941 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 89.0;kidney: 43.9;liver: 79.9" "Group enriched" "Detected in some" 5 "Distal enterocytes: 102.0;Enteroendocrine cells: 41.5;Hepatocytes: 43.0;Intestinal goblet cells: 75.3;Paneth cells: 95.9;Proximal enterocytes: 155.4;Proximal tubular cells: 68.3;Undifferentiated cells: 45.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 45.3;renal cancer: 30.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 41 "OE19: 96.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA014482 Approved NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "HPA014482: AB_2082885" "unprognostic (7.34e-3)" "unprognostic (1.55e-1)" "unprognostic (1.41e-2)" "unprognostic (1.46e-3)" "unprognostic (1.22e-2)" "unprognostic (1.06e-1)" "unprognostic (5.08e-2)" "unprognostic (2.62e-1)" "unprognostic (6.22e-2)" "unprognostic (4.67e-1)" "unprognostic (8.86e-2)" "prognostic favorable (8.98e-4)" "unprognostic (1.74e-1)" "unprognostic (2.89e-3)" "unprognostic (3.00e-2)" 0.6 0.1 0.4 5.6 0.4 0.0 0.3 0.3 0.5 0.0 0.3 71.1 73.4 0.1 0.0 0.0 0.0 15.2 0.0 0.4 0.3 43.9 79.9 0.0 0.1 0.3 0.3 0.0 0.3 0.0 0.2 0.0 0.4 0.0 70.3 0.0 0.0 0.2 0.0 0.0 89.0 1.7 0.3 0.1 1.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 96.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.4 0.3 0.5 0.4 0.3 0.3 0.3 0.4 0.3 0.4 0.4 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 102.0 15.6 0.4 0.0 0.2 0.0 0.1 41.5 0.0 0.4 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.4 43.0 0.0 0.0 0.1 75.3 0.0 0.6 0.0 0.0 0.0 0.5 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.5 95.9 0.0 0.0 0.0 155.4 68.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 45.6 0.0 CLTRN "NX17, TMEM27" ENSG00000147003 "Collectrin, amino acid transport regulator" Q9HBJ8 X 15627318-15675012 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "kidney: 486.4" "Cell type enriched" "Detected in some" 16 "Proximal tubular cells: 885.4" "Cancer enriched" "Detected in many" 35 "renal cancer: 106.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 8.5;hTERT-HME1: 5.2;RPTEC TERT1: 8.5;SuSa: 5.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA048543 Enhanced Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Endoplasmic reticulum, Vesicles" "HPA048543: AB_2680436" "unprognostic (1.27e-1)" "unprognostic (4.77e-2)" "unprognostic (2.45e-2)" "unprognostic (2.66e-2)" "unprognostic (5.20e-2)" "unprognostic (5.23e-2)" "unprognostic (1.25e-1)" "unprognostic (8.50e-2)" "unprognostic (1.90e-2)" "prognostic favorable (5.65e-4)" "unprognostic (1.05e-2)" "unprognostic (3.03e-1)" "prognostic favorable (6.78e-9)" "unprognostic (1.77e-1)" "unprognostic (2.60e-2)" "unprognostic (2.58e-1)" "unprognostic (1.33e-2)" 0.5 0.8 0.5 0.0 0.6 0.3 2.0 0.7 0.8 1.0 16.6 0.6 1.3 1.5 3.1 0.6 2.4 3.7 1.1 0.7 0.6 486.4 61.5 1.7 0.4 0.6 0.5 3.2 5.3 10.5 0.6 0.5 0.6 1.5 0.3 1.2 0.8 1.3 0.1 1.2 0.4 0.4 0.4 0.2 10.9 1.0 0.5 0.8 4.1 0.1 0.3 0.8 0.4 0.9 2.3 1.8 1.1 0.3 0.7 1.0 0.7 0.0 0.0 0.1 0.1 0.1 0.5 0.1 1.6 0.2 0.2 8.5 0.7 2.3 0.0 0.3 0.7 0.2 0.0 0.8 1.0 0.0 0.0 0.2 2.0 0.3 5.2 0.6 0.0 2.1 0.5 0.4 0.2 2.8 0.1 0.3 2.9 0.8 2.6 0.2 0.3 0.9 8.5 0.1 1.1 1.0 0.6 0.1 1.8 5.1 0.6 0.2 0.0 0.2 0.4 0.3 0.0 0.4 0.2 0.3 0.6 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.2 0.1 0.1 0.2 0.6 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.6 0.7 0.8 0.7 0.6 0.6 0.5 0.6 0.4 0.5 0.9 0.1 0.0 4.1 0.0 5.7 0.0 0.0 0.0 0.0 0.0 3.0 3.2 0.0 0.0 1.8 27.6 0.0 2.1 0.0 0.0 54.8 25.1 0.0 2.8 0.6 0.1 0.0 0.0 0.0 0.6 0.5 0.3 0.0 3.3 0.0 1.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 885.4 2.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.0 3.7 0.5 0.0 0.0 CMBL FLJ23617 ENSG00000164237 "Carboxymethylenebutenolidase homolog" Q96DG6 5 10275875-10307902 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 168.5;liver: 172.4;skeletal muscle: 164.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 185.2;Distal tubular cells: 215.2;Proximal enterocytes: 716.0;Proximal tubular cells: 465.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 48.5;K-562: 51.4;PC-3: 46.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036571 Uncertain NA NA 580000 "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036571: AB_10670114" "unprognostic (1.81e-2)" "unprognostic (2.55e-1)" "unprognostic (8.10e-3)" "unprognostic (2.53e-2)" "unprognostic (2.01e-1)" "unprognostic (2.30e-1)" "unprognostic (1.07e-1)" "unprognostic (3.20e-1)" "unprognostic (8.64e-2)" "prognostic favorable (1.99e-4)" "unprognostic (1.76e-1)" "unprognostic (4.44e-2)" "unprognostic (1.29e-2)" "unprognostic (2.12e-1)" "unprognostic (1.16e-1)" "unprognostic (1.52e-1)" "unprognostic (2.44e-1)" 11.3 31.5 8.9 3.8 8.7 4.0 10.6 7.2 10.2 7.2 8.1 53.6 95.8 8.5 9.9 3.8 13.5 14.2 22.9 8.5 8.5 168.5 172.4 6.8 1.2 8.5 8.9 23.3 16.6 26.6 10.6 2.1 9.0 14.3 34.7 1.3 9.6 7.4 164.4 2.8 85.0 6.4 8.0 2.7 28.5 3.2 10.0 2.9 9.8 42.4 0.5 9.7 6.4 7.7 5.9 7.2 8.2 20.3 32.0 35.7 41.2 9.7 11.1 3.0 4.5 3.0 30.9 0.1 15.4 7.8 14.5 0.1 19.7 12.8 4.1 0.3 13.4 27.4 28.6 24.3 9.8 0.2 0.2 48.5 8.5 6.7 6.1 11.7 9.4 0.0 51.4 0.4 11.6 1.3 0.1 1.1 12.1 0.0 46.0 5.9 0.0 0.6 32.2 3.8 6.3 9.7 23.1 2.2 0.7 9.7 16.7 1.0 2.7 4.6 6.0 7.6 0.1 0.2 0.1 0.1 8.0 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 8.9 8.7 7.2 10.2 8.5 8.5 8.5 8.9 9.0 8.0 10.0 7.7 4.0 25.6 17.2 2.9 2.2 3.7 17.8 6.3 14.8 2.0 40.1 16.8 86.0 55.8 14.8 23.9 4.2 15.3 0.9 185.2 215.2 10.7 3.2 26.5 25.8 7.1 19.2 56.1 5.0 15.6 10.6 37.1 133.0 19.2 13.3 47.4 14.3 161.2 12.1 0.0 6.9 100.5 2.0 4.1 3.8 3.5 47.8 5.5 1.8 1.9 0.4 17.5 1.0 4.0 0.4 16.1 118.6 41.3 0.5 17.5 716.0 465.4 13.0 3.1 0.0 31.0 12.7 1.0 5.9 5.2 3.8 4.9 4.4 145.0 162.7 15.6 CNDP1 "CN1, CPGL2, HsT2308, MGC10825" ENSG00000150656 "Carnosine dipeptidase 1" Q96KN2 18 74534500-74587212 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 85.6" "Cell type enriched" "Detected in some" 10 "Oligodendrocytes: 361.7" "Cancer enhanced" "Detected in some" "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 38 "U-266/84: 15.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008933, HPA073283" Enhanced "Secreted to blood" NA NA 2100000000 "Cluster 70: Brain - Nervous system development" "Cluster 16: U-266 - Nucleosome" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA008933: AB_1847033, HPA073283: " "unprognostic (7.43e-3)" "unprognostic (6.00e-2)" "unprognostic (8.55e-3)" "unprognostic (3.93e-1)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (8.04e-3)" "unprognostic (1.12e-2)" "unprognostic (2.81e-1)" "unprognostic (1.16e-1)" "unprognostic (1.16e-1)" "unprognostic (1.66e-1)" "unprognostic (6.90e-3)" "unprognostic (1.14e-1)" "unprognostic (3.30e-2)" "unprognostic (1.33e-1)" "unprognostic (1.28e-1)" 0.0 0.0 27.4 0.0 74.2 0.1 0.0 80.4 39.0 0.0 6.0 0.0 1.3 0.0 0.7 0.0 0.0 0.1 0.0 30.5 51.3 0.5 12.9 0.0 0.0 85.6 76.9 0.0 0.0 0.0 0.2 0.0 74.3 0.1 0.0 0.1 0.0 0.1 1.4 0.1 0.2 0.0 39.7 0.0 0.0 0.3 74.9 0.0 0.2 0.0 0.0 0.0 0.0 80.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 15.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 27.4 74.2 80.4 39.0 30.5 51.3 85.6 76.9 74.3 39.7 74.9 80.7 0.2 0.0 0.0 0.3 0.2 0.1 0.4 0.2 0.0 0.6 0.5 0.3 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 8.6 0.5 0.2 0.2 0.0 2.7 1.2 0.2 0.0 0.3 0.0 1.5 0.0 0.2 0.7 35.1 0.1 0.0 1.5 0.7 0.0 1.2 1.1 3.1 0.0 0.2 0.0 1.0 0.0 0.5 0.0 3.0 361.7 0.2 0.1 0.0 0.0 0.4 0.4 24.5 0.0 1.0 0.0 0.6 0.2 1.0 0.4 0.0 0.3 0.0 0.4 0.0 0.5 0.2 COL19A1 ENSG00000082293 "Collagen type XIX alpha 1 chain" Q14993 6 69866556-70212468 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Myogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.1;lymphoid tissue: 3.2" "Cell type enhanced" "Detected in some" "B-cells: 33.5;Excitatory neurons: 66.6;Inhibitory neurons: 164.2;Oligodendrocyte precursor cells: 39.7" "Cancer enhanced" "Detected in single" "melanoma: 0.7" "Region enhanced" "Detected in many" "cerebellum: 9.1" "Group enriched" "Detected in some" 218 "memory B-cell: 14.6;naive B-cell: 31.9" "Lineage enriched" "Detected in single" 299 "B-cells: 31.9" "Cell line enhanced" "Detected in some" "HDLM-2: 5.3;RH-30: 11.4;SCLC-21H: 3.7;SH-SY5Y: 2.9;SK-MEL-30: 9.6;WM-115: 9.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA042422 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA042422: AB_10794798" "unprognostic (2.65e-2)" "unprognostic (2.55e-1)" "unprognostic (2.71e-1)" "unprognostic (9.24e-2)" "unprognostic (2.26e-2)" "unprognostic (6.20e-2)" "unprognostic (3.17e-1)" "unprognostic (1.10e-3)" "unprognostic (3.41e-1)" "unprognostic (1.28e-1)" "unprognostic (2.76e-1)" "unprognostic (1.62e-2)" "unprognostic (1.31e-2)" "unprognostic (1.73e-1)" "unprognostic (2.20e-1)" "unprognostic (3.35e-1)" "unprognostic (8.91e-2)" 0.0 0.1 1.2 1.5 1.6 0.3 0.0 9.1 1.9 0.0 0.0 0.5 0.2 0.0 0.0 0.1 0.1 0.1 0.7 2.3 0.1 1.4 0.1 0.0 2.6 0.2 0.2 0.0 0.2 0.0 0.6 0.0 0.3 0.7 0.7 0.6 0.1 0.0 0.7 0.0 0.7 0.0 0.0 1.6 1.1 0.4 0.0 1.1 0.0 0.2 3.2 2.2 0.2 2.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 5.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 11.4 0.0 0.0 0.0 3.7 2.9 0.0 0.0 9.6 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.0 0.0 31.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.2 1.6 9.1 1.9 2.3 0.1 0.2 0.2 0.3 0.0 0.0 2.1 0.0 0.0 0.0 11.1 33.5 0.1 0.2 0.0 0.0 4.4 0.1 0.0 2.5 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.2 0.0 0.0 66.6 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.7 0.1 0.0 0.0 164.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.8 8.4 0.3 0.1 1.0 39.7 10.6 0.0 0.0 0.0 0.9 0.0 0.0 3.8 0.7 0.1 0.0 11.2 0.4 1.8 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 COX6A2 ENSG00000156885 "Cytochrome c oxidase subunit 6A2" Q02221 16 31427731-31428360 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Oxidoreductase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 46 "heart muscle: 3905.3;skeletal muscle: 6742.0;tongue: 2096.1" "Cell type enriched" "Detected in some" 18 "Cardiomyocytes: 4861.8" "Group enriched" "Detected in many" 5 "head and neck cancer: 9.3;liver cancer: 2.9;prostate cancer: 3.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 150 "NK-cell: 15.0" "Lineage enriched" "Detected in single" 150 "NK-cells: 15.0" "Cell line enriched" "Detected in some" 4 "U-266/84: 13.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 16: U-266 - Nucleosome" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (1.66e-1)" "unprognostic (1.73e-3)" "unprognostic (2.09e-2)" "unprognostic (1.25e-2)" "unprognostic (1.68e-2)" "unprognostic (3.88e-1)" "unprognostic (5.61e-2)" "unprognostic (7.20e-2)" "unprognostic (8.71e-2)" "unprognostic (6.20e-2)" "unprognostic (1.68e-1)" "unprognostic (2.65e-1)" 1.9 0.9 1.8 0.1 1.3 0.0 2.9 2.3 2.3 0.4 0.2 1.4 1.1 1.0 0.0 74.8 0.9 0.0 3905.3 0.9 2.1 4.5 15.9 3.3 0.4 1.6 2.6 1.2 3.0 2.9 11.9 0.1 7.3 38.9 0.0 1.0 92.1 0.1 6742.0 3.5 1.2 0.0 0.8 0.5 1.3 1.3 2.6 0.5 2.0 2096.1 0.1 0.3 1.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.1 1.8 1.3 2.3 2.3 0.9 2.1 1.6 2.6 7.3 0.8 2.6 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.2 0.4 4861.8 2.8 0.0 3.7 0.0 0.0 0.4 0.0 5.9 0.0 0.0 0.0 0.1 48.8 0.0 0.0 0.0 0.4 0.0 96.2 0.0 0.1 0.0 0.2 0.4 75.7 2.9 3.3 0.0 0.1 0.0 1.6 0.0 0.8 0.3 1.3 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.1 1.3 24.9 0.0 4.2 19.7 258.0 53.7 0.2 1.2 0.0 0.0 0.0 2.1 0.0 0.0 0.0 CPN2 ACBP ENSG00000178772 "Carboxypeptidase N subunit 2" P22792 3 194339768-194351328 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "liver: 218.6" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 171.8" "Cancer enriched" "Detected in some" 32 "liver cancer: 72.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 29 "Hep G2: 61.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA004732 Uncertain "Secreted to blood" NA NA 25000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA004732: AB_1078561" "unprognostic (4.27e-2)" "unprognostic (3.04e-1)" "unprognostic (1.42e-1)" "unprognostic (4.12e-2)" "prognostic favorable (2.05e-4)" "unprognostic (1.27e-1)" "unprognostic (8.65e-2)" "unprognostic (8.56e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (2.91e-2)" "unprognostic (2.40e-1)" "unprognostic (6.90e-5)" "unprognostic (8.42e-2)" 0.4 3.0 0.7 0.4 0.6 1.5 0.2 0.6 1.1 0.2 0.0 0.2 0.0 0.4 0.4 0.1 0.2 0.4 1.0 0.7 0.8 14.7 218.6 0.2 0.3 0.2 0.2 0.3 0.1 0.1 0.0 0.4 0.2 0.2 0.2 1.1 0.2 0.1 0.1 0.6 0.2 0.2 0.0 1.2 0.4 0.7 0.4 0.1 0.3 0.0 0.2 0.1 0.0 1.1 0.2 0.1 0.3 0.3 0.1 0.8 0.2 0.3 0.1 0.0 0.0 0.4 0.2 0.2 0.3 0.8 0.4 0.5 0.1 0.0 0.2 0.1 0.2 0.3 0.6 61.8 0.0 0.3 0.1 0.1 0.0 0.2 0.1 0.3 0.0 0.3 0.5 0.6 0.0 0.3 0.2 0.3 0.3 0.1 0.1 0.1 0.5 0.0 0.1 0.4 0.3 0.2 0.3 0.2 0.4 0.3 0.2 1.4 1.6 0.2 2.1 0.2 0.1 0.2 0.2 0.1 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.6 1.1 0.7 0.8 0.2 0.2 0.2 0.0 0.4 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.9 171.8 0.2 0.0 0.3 0.0 0.0 2.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 CRB2 "FLJ16786, FLJ38464" ENSG00000148204 "Crumbs cell polarity complex component 2" Q5IJ48 9 123356170-123380324 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Gastrulation, Sensory transduction, Vision" "Developmental protein" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 24.9;choroid plexus: 14.1;retina: 8.1" "Cell type enhanced" "Detected in some" "Astrocytes: 40.5;Bipolar cells: 29.7;Cone photoreceptor cells: 118.9;Oligodendrocytes: 26.8;Rod photoreceptor cells: 110.1" "Group enriched" "Detected in some" 7 "glioma: 9.4;ovarian cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "AF22: 32.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA043674 Approved Supported "Intracellular and membrane" NA NA 210000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA043674: AB_10962974" "unprognostic (1.38e-2)" "unprognostic (2.39e-2)" "unprognostic (1.26e-1)" "unprognostic (2.83e-4)" "unprognostic (2.85e-2)" "unprognostic (1.14e-2)" "unprognostic (2.31e-1)" "unprognostic (3.69e-4)" "unprognostic (1.20e-1)" "unprognostic (7.28e-3)" "unprognostic (4.66e-3)" "unprognostic (3.09e-1)" "unprognostic (5.56e-5)" "unprognostic (1.31e-1)" "unprognostic (1.55e-1)" "unprognostic (4.38e-2)" "unprognostic (3.38e-1)" 1.6 0.0 14.5 0.5 21.5 0.3 0.1 11.0 12.5 0.0 14.1 0.7 0.1 1.5 0.1 0.0 1.0 0.0 0.1 13.8 13.7 5.8 0.0 0.0 0.7 24.0 20.3 0.2 0.0 0.0 1.4 0.0 14.9 0.0 0.4 8.1 0.0 0.0 0.0 0.1 0.3 0.3 22.2 0.5 0.2 0.5 24.9 0.2 0.1 0.0 0.6 0.2 0.0 23.0 0.0 0.1 32.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.5 0.1 0.3 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.2 0.0 0.6 0.0 0.0 4.3 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.7 1.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 21.5 11.0 12.5 13.8 13.7 24.0 20.3 14.9 22.2 24.9 23.0 0.0 0.0 0.0 40.5 0.5 0.3 0.1 0.0 0.0 29.7 0.0 2.2 2.8 0.0 0.0 1.8 118.9 0.1 0.0 0.7 0.0 0.0 3.9 0.4 1.3 0.4 3.0 0.0 4.2 0.0 0.1 2.5 0.0 0.1 1.3 0.0 0.0 0.0 0.2 3.3 0.4 2.8 0.0 0.0 1.0 7.7 1.8 0.1 0.0 0.0 0.1 6.1 1.0 2.0 26.8 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 110.1 0.0 0.5 0.3 0.1 0.3 0.0 0.6 0.3 0.1 0.1 5.3 0.1 CRYBB1 ENSG00000100122 "Crystallin beta B1" P53674 22 26599278-26618027 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 9.6" "Cell type enriched" "Detected in some" 21 "Hofbauer cells: 82.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 10.3;non-classical monocyte: 7.5" "Lineage enriched" "Detected in many" 7 "monocytes: 10.3" "Group enriched" "Detected in some" 5 "Karpas-707: 43.3;RPMI-8226: 82.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA003448, CAB010058" Supported NA NA 89000 "Cluster 51: Monocytes - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB010058: AB_668166, HPA003448: AB_2732396" "unprognostic (1.31e-1)" "unprognostic (5.56e-3)" "unprognostic (1.39e-2)" "unprognostic (1.44e-2)" "unprognostic (2.29e-1)" "unprognostic (2.18e-1)" "unprognostic (7.89e-3)" "unprognostic (1.51e-1)" "unprognostic (9.51e-2)" "unprognostic (1.05e-1)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "unprognostic (3.88e-4)" "unprognostic (2.62e-2)" "unprognostic (1.23e-2)" "unprognostic (3.22e-1)" "unprognostic (1.76e-2)" 1.3 1.6 1.5 0.9 1.6 0.6 0.6 1.6 2.4 0.6 1.3 0.5 0.4 0.3 9.6 0.4 0.4 1.2 0.4 1.6 1.6 0.2 0.4 0.5 1.2 1.9 1.8 0.2 0.2 0.3 0.5 3.3 2.3 0.2 0.4 0.0 0.4 0.2 0.1 0.1 0.4 0.9 1.9 1.6 0.3 0.3 2.2 0.4 0.2 0.2 0.5 1.1 0.2 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 1.5 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 43.3 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.8 0.0 82.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 4.6 0.0 0.2 0.5 0.0 0.0 0.7 0.2 1.8 0.0 2.2 0.0 0.0 1.0 0.0 0.0 10.3 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.4 0.5 7.5 0.0 0.0 0.6 1.5 1.6 1.6 2.4 1.6 1.6 1.9 1.8 2.3 1.9 2.2 2.1 0.1 0.0 0.0 0.7 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.1 1.3 0.0 0.0 0.9 0.0 0.5 0.2 0.0 0.1 1.3 0.0 0.0 0.2 82.6 0.0 0.2 0.0 0.0 3.5 0.8 0.6 0.0 2.8 1.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.2 0.0 0.0 CRYM DFNA40 ENSG00000103316 "Crystallin mu" Q14894 16 21238874-21303083 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 78.7;heart muscle: 175.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 126.0;Ionocytes: 114.0;Muller glia cells: 640.7;Proximal tubular cells: 190.1" "Cancer enhanced" "Detected in many" "prostate cancer: 14.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 21 "plasmacytoid DC: 82.0" "Lineage enriched" "Detected in many" 21 "dendritic cells: 82.0" "Cell line enriched" "Detected in some" 4 "RPTEC TERT1: 100.3" "Group enriched" "Detected in all" 11 "amygdala: 124.0;basal ganglia: 275.1;cerebral cortex: 124.7;hippocampal formation: 324.3;white matter: 128.4" "Low region specificity" "Detected in all" "HPA019086, HPA030619" Enhanced Supported Cytosol NA NA 150000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 5: Muller glia cells - Visual perception" Cytosol "HPA019086: AB_1847260, HPA030619: AB_2673551" "unprognostic (1.32e-1)" "unprognostic (2.93e-3)" "unprognostic (8.96e-2)" "unprognostic (1.44e-1)" "unprognostic (2.13e-1)" "unprognostic (4.62e-2)" "unprognostic (2.88e-1)" "unprognostic (5.75e-3)" "unprognostic (2.81e-1)" "unprognostic (7.37e-2)" "unprognostic (2.05e-2)" "unprognostic (5.95e-2)" "unprognostic (2.11e-3)" "unprognostic (7.79e-3)" "unprognostic (2.49e-2)" "unprognostic (1.87e-3)" "unprognostic (1.31e-1)" 1.9 0.8 37.4 0.9 78.7 1.0 2.7 40.6 62.2 3.7 13.6 6.9 1.6 1.0 0.2 7.6 1.1 7.0 175.3 54.0 31.6 64.4 14.2 8.5 1.1 13.9 19.8 0.3 1.8 8.9 55.6 0.4 15.6 35.4 8.4 54.7 20.6 0.2 13.4 4.1 2.6 0.3 14.1 0.3 1.3 5.1 20.5 0.3 0.4 0.9 3.8 21.8 3.6 31.3 0.2 4.0 0.0 0.0 0.2 0.4 0.7 0.0 2.1 0.1 0.2 0.2 0.2 0.3 1.0 0.0 1.8 0.6 5.4 0.0 0.0 0.0 0.8 23.2 0.1 2.3 0.0 0.1 2.2 0.8 0.0 0.8 1.0 0.0 0.0 0.5 0.0 0.4 0.7 0.3 0.0 0.9 9.7 1.6 0.1 0.1 0.0 0.5 100.3 0.1 3.7 5.2 0.2 0.1 2.6 4.8 0.1 0.0 0.0 0.5 0.7 6.8 0.0 0.2 0.0 0.5 16.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.2 0.0 0.0 0.1 3.9 0.0 0.0 0.3 0.0 0.0 82.0 0.0 1.2 37.4 78.7 40.6 62.2 54.0 31.6 13.9 19.8 15.6 14.1 20.5 31.3 0.3 0.0 20.1 5.2 4.1 2.3 25.4 16.3 0.0 6.3 0.4 11.7 126.0 2.8 56.1 14.7 4.2 0.0 11.4 7.1 17.6 0.1 19.7 3.2 1.5 3.0 13.1 4.8 43.8 0.0 0.0 7.1 6.1 7.7 1.3 1.3 0.4 8.3 0.1 1.7 5.9 20.6 114.0 1.6 0.7 12.4 0.0 1.5 33.8 10.3 0.7 640.7 0.0 7.1 6.6 0.4 2.8 0.0 0.3 19.0 7.5 190.1 19.9 26.2 0.0 0.2 4.3 6.7 7.3 0.2 1.3 0.1 1.1 0.1 8.2 68.0 CTXN3 ENSG00000205279 "Cortexin 3" Q4LDR2 5 127649044-127658630 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "kidney: 79.8" "Cell type enriched" "Detected in some" 8 "Proximal tubular cells: 201.3" "Cancer enriched" "Detected in single" 8 "renal cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (7.32e-2)" "unprognostic (9.88e-2)" "unprognostic (1.19e-1)" "unprognostic (1.29e-1)" "unprognostic (6.20e-3)" 0.0 0.0 3.1 0.0 4.2 0.0 0.0 1.9 10.2 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.1 4.8 79.8 0.0 0.1 0.0 8.3 11.8 0.0 0.0 0.2 5.3 0.0 10.2 0.5 0.0 0.2 0.2 0.0 12.9 0.0 0.0 0.0 2.6 0.0 0.0 0.1 5.3 0.1 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 4.2 1.9 10.2 5.1 4.8 8.3 11.8 10.2 2.6 5.3 3.6 0.0 0.0 0.0 1.0 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 23.5 0.0 0.7 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 201.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 CUBN "gp280, IFCR, MGA1" ENSG00000107611 Cubilin O60494 10 16823966-17129811 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol metabolism, Endocytosis, Lipid metabolism, Protein transport, Steroid metabolism, Sterol metabolism, Transport" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 140.4" "Group enriched" "Detected in many" 7 "Proximal enterocytes: 257.7;Proximal tubular cells: 325.0" "Cancer enriched" "Detected in some" 15 "renal cancer: 24.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 14.8;ASC TERT1: 3.0;SK-MEL-30: 2.8;WM-115: 5.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004133, HPA043854" Enhanced "Intracellular and membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA004133: AB_2732398, HPA043854: AB_2732510" "unprognostic (1.75e-1)" "unprognostic (2.35e-1)" "unprognostic (2.12e-3)" "unprognostic (8.61e-4)" "unprognostic (9.54e-2)" "unprognostic (2.78e-2)" "unprognostic (2.88e-2)" "unprognostic (7.03e-2)" "unprognostic (1.24e-1)" "unprognostic (7.16e-2)" "unprognostic (1.98e-2)" "unprognostic (2.47e-1)" "prognostic favorable (1.12e-4)" "unprognostic (6.24e-3)" "unprognostic (1.97e-1)" "unprognostic (2.00e-1)" "unprognostic (1.93e-1)" 0.7 0.8 0.8 0.4 0.9 0.4 0.8 0.8 0.7 1.2 1.3 0.5 0.2 0.7 3.1 0.2 2.1 0.3 0.6 0.8 0.8 140.4 0.1 0.6 0.8 2.5 1.7 2.5 0.5 0.6 2.2 2.6 2.4 1.1 0.2 3.0 0.7 0.4 0.3 0.8 28.0 0.4 1.7 0.9 0.4 2.0 1.0 1.7 3.8 0.5 0.7 0.4 0.7 0.6 0.0 0.0 1.5 14.8 0.5 3.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.8 1.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.5 0.0 0.6 1.5 0.6 0.1 0.2 0.2 0.0 0.2 0.1 0.2 0.0 0.1 0.0 0.2 0.0 0.4 0.0 0.0 0.3 0.0 0.0 2.8 0.1 0.0 0.1 1.6 0.1 0.2 0.3 0.1 0.5 0.0 0.0 0.4 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.9 0.8 0.7 0.8 0.8 2.5 1.7 2.4 1.7 1.0 0.6 3.2 0.0 1.5 23.8 3.7 0.5 0.4 0.2 0.6 2.9 0.6 0.6 1.7 0.0 3.2 5.5 2.1 0.0 3.3 0.1 13.7 0.0 37.3 3.1 2.2 5.7 0.0 0.0 8.4 0.2 0.0 2.3 0.0 2.2 0.0 2.2 1.4 0.0 0.1 0.0 9.0 3.7 0.0 0.3 0.4 31.8 2.8 3.1 7.2 7.5 0.1 6.5 1.0 9.0 5.5 0.1 5.0 1.2 1.6 0.4 257.7 325.0 3.5 4.0 0.0 19.0 1.6 1.1 0.9 0.1 0.9 0.1 2.9 1.2 1.2 0.2 CYB5A CYB5 ENSG00000166347 "Cytochrome b5 type A" P00167 18 74250846-74291973 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 889.6;liver: 2472.0" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 1371.0;Distal tubular cells: 2156.1;Hepatocytes: 3376.3;Proximal enterocytes: 1856.4;Proximal tubular cells: 3630.6" "Cancer enhanced" "Detected in all" "liver cancer: 43.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1117.0;RT4: 513.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006333, HPA047548, HPA058547" Enhanced Enhanced Vesicles,Cytosol No No 1400000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "CAB006333: , HPA047548: AB_2680084, HPA058547: AB_2683750" "unprognostic (1.88e-1)" "unprognostic (1.28e-1)" "prognostic favorable (5.23e-4)" "unprognostic (1.08e-2)" "unprognostic (1.41e-1)" "unprognostic (9.14e-2)" "prognostic favorable (4.15e-4)" "unprognostic (7.79e-3)" "unprognostic (1.11e-1)" "unprognostic (3.33e-2)" "unprognostic (2.68e-2)" "unprognostic (1.65e-2)" "unprognostic (1.17e-1)" "unprognostic (1.95e-1)" "unprognostic (1.75e-1)" "unprognostic (4.64e-2)" "unprognostic (8.54e-2)" 309.5 109.6 38.4 31.2 39.7 25.3 253.5 42.2 45.2 86.0 37.6 146.5 438.2 44.9 176.2 78.1 81.9 301.2 84.8 37.5 38.8 889.6 2472.0 356.6 43.7 43.1 39.7 223.9 461.3 236.0 58.5 81.8 41.9 95.9 103.4 10.3 59.1 122.8 41.4 118.4 381.7 46.7 40.8 75.6 194.8 57.9 40.0 51.6 42.5 42.1 35.2 155.5 68.3 43.5 78.8 130.8 67.4 0.6 1117.0 198.2 89.5 52.6 113.8 111.0 163.8 156.2 82.7 95.6 36.7 97.6 54.4 170.6 0.1 73.1 86.9 179.8 91.7 34.9 65.6 418.1 174.6 67.3 44.1 334.1 57.4 63.0 32.3 66.0 63.6 85.8 58.6 35.0 93.7 140.9 38.3 80.5 30.4 110.0 86.8 93.6 21.9 2.3 111.9 513.2 190.4 79.7 51.4 137.1 65.8 56.6 271.5 63.7 57.9 0.6 85.8 26.6 68.1 24.6 109.2 30.3 67.0 19.2 64.3 4.1 29.5 7.5 51.3 36.3 116.2 93.7 55.6 60.2 53.7 112.7 54.5 68.6 3.7 36.3 45.7 47.8 48.8 43.2 38.4 39.7 42.2 45.2 37.5 38.8 43.1 39.7 41.9 40.8 40.0 43.5 169.7 637.8 1371.0 11.4 76.0 98.0 82.1 368.6 50.7 9.9 345.8 213.2 90.7 836.4 1053.2 842.4 4.2 229.3 29.4 197.0 2156.1 239.4 7.5 163.1 76.6 119.9 164.2 180.0 13.1 504.6 169.8 141.4 208.9 345.6 39.9 55.0 177.4 3376.3 97.4 8.4 12.6 236.5 457.7 128.6 72.9 26.7 158.1 60.8 90.7 10.3 224.1 39.2 32.0 14.1 22.7 266.7 358.9 149.7 33.4 142.0 1856.4 3630.6 619.5 14.0 52.6 49.6 85.0 15.3 42.0 141.2 223.9 44.5 52.6 1123.6 329.9 220.7 CYP27B1 "CYP1, P450c1, PDDR, VDD1" ENSG00000111012 "Cytochrome P450 family 27 subfamily B member 1" O15528 12 57762334-57768986 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 15.2;thyroid gland: 5.7" "Group enriched" "Detected in many" 5 "Exocrine glandular cells: 22.1;monocytes: 22.8;Proximal tubular cells: 36.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "MAIT T-cell: 1.2" "Lineage enriched" "Detected in single" 12 "T-cells: 1.2" "Cell line enhanced" "Detected in many" "hTERT-HME1: 13.6;RH-30: 22.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (8.59e-2)" "unprognostic (1.42e-1)" "unprognostic (8.89e-2)" "unprognostic (2.77e-2)" "unprognostic (4.16e-2)" "unprognostic (1.03e-2)" "unprognostic (1.28e-2)" "unprognostic (1.44e-1)" "unprognostic (2.10e-2)" "unprognostic (4.72e-2)" "unprognostic (2.51e-1)" "unprognostic (1.17e-2)" "unprognostic (1.75e-3)" "unprognostic (4.10e-2)" "unprognostic (3.19e-2)" "prognostic unfavorable (6.79e-4)" "unprognostic (5.67e-3)" 0.3 0.9 0.3 0.7 0.3 0.8 0.8 0.3 0.4 0.2 0.3 0.4 0.4 0.2 0.6 0.4 0.2 0.5 0.1 0.3 0.3 15.2 0.6 0.5 0.9 0.3 0.3 0.2 1.6 1.0 0.4 0.3 0.3 0.3 0.6 3.3 0.5 0.2 0.1 0.6 0.5 0.1 0.3 0.2 0.5 0.4 0.3 0.2 5.7 0.0 0.7 2.2 0.2 0.5 2.8 0.4 0.0 0.3 0.2 0.4 1.1 0.1 3.1 1.0 0.3 3.7 1.0 2.0 0.1 0.4 0.3 3.3 0.5 5.9 3.1 0.6 0.4 0.9 0.0 1.0 0.3 1.2 2.5 0.5 1.9 0.8 13.6 1.2 0.4 2.6 1.3 1.2 0.4 0.4 0.4 1.1 1.3 2.8 2.3 0.8 22.6 1.7 0.5 0.3 0.7 0.8 2.0 0.4 0.1 0.1 1.7 2.3 0.2 0.2 1.6 1.1 0.4 1.4 1.2 0.4 1.2 2.6 1.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.4 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.5 0.5 0.0 0.0 0.7 3.0 5.2 1.3 1.1 0.6 0.7 5.1 2.7 0.7 2.8 1.9 0.0 2.1 0.1 0.0 0.6 1.9 2.0 0.9 1.1 0.5 0.5 0.0 0.0 0.3 22.1 0.4 0.6 0.0 1.7 4.5 0.4 0.4 0.3 2.3 0.0 0.2 0.6 0.0 0.3 0.8 0.0 0.0 1.5 0.0 0.0 22.8 0.6 0.0 0.0 0.1 5.4 0.1 0.4 1.7 1.4 0.5 36.9 0.6 5.2 0.0 1.5 1.1 0.3 0.7 1.3 2.7 0.1 0.5 0.4 0.9 0.6 CYP2B6 "CPB6, CYP2B, CYPIIB6" ENSG00000197408 "Cytochrome P450 family 2 subfamily B member 6" P20813 19 40991282-41018398 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "liver: 533.7" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 420.9" "Cancer enhanced" "Detected in many" "liver cancer: 28.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 2.6;OE19: 1.8" "Region enhanced" "Detected in single" "spinal cord: 2.3" "CAB033866, HPA048124, HPA062973" Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "Nuclear membrane" "Nucleoplasm, Cytosol" "CAB033866: AB_2292644, HPA048124: AB_2680274, HPA062973: AB_2684914" "unprognostic (1.86e-1)" "unprognostic (1.23e-2)" "unprognostic (1.13e-2)" "unprognostic (6.13e-2)" "unprognostic (4.59e-2)" "unprognostic (4.63e-2)" "unprognostic (4.41e-2)" "unprognostic (1.73e-1)" "unprognostic (5.78e-2)" "unprognostic (1.04e-3)" "unprognostic (2.19e-1)" "unprognostic (9.43e-2)" "unprognostic (5.44e-1)" 0.0 0.0 0.2 0.2 0.2 0.5 0.1 0.6 0.3 0.0 0.3 4.7 5.1 0.1 0.0 0.0 0.0 0.7 0.1 0.3 0.1 15.1 533.7 0.4 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 1.7 0.8 0.0 0.1 0.2 0.0 6.7 0.6 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.1 0.0 2.6 0.1 0.0 0.0 0.1 0.2 0.1 0.3 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.5 0.2 1.8 0.1 0.0 0.1 0.1 0.6 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.2 0.4 0.3 0.2 0.1 0.2 0.2 0.1 0.3 0.3 0.0 0.4 0.0 0.7 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.5 0.1 0.0 0.4 0.1 0.0 0.2 0.2 0.6 0.3 0.3 0.1 0.3 0.1 0.2 0.0 0.2 0.4 0.0 0.0 1.1 0.0 0.8 0.0 0.2 0.4 0.0 0.0 0.1 0.0 0.2 7.2 1.4 1.8 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 16.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 11.4 420.9 0.0 0.0 0.1 1.6 0.0 11.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.3 0.0 0.0 0.1 38.3 16.9 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.1 4.3 0.7 CYP4A11 "CYP4A2, CYP4AII" ENSG00000187048 "Cytochrome P450 family 4 subfamily A member 11" Q02928 1 46929177-46941484 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 333 "kidney: 218.8;liver: 857.1" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 563.8" "Cancer enriched" "Detected in some" 5 "liver cancer: 73.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 85: Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (9.05e-2)" "unprognostic (4.98e-2)" "unprognostic (4.43e-2)" "unprognostic (4.11e-1)" "unprognostic (7.81e-5)" "unprognostic (5.10e-3)" "unprognostic (1.16e-2)" "unprognostic (1.83e-2)" "unprognostic (1.92e-2)" "unprognostic (1.90e-1)" "unprognostic (1.12e-1)" "unprognostic (4.59e-2)" "unprognostic (5.86e-2)" "unprognostic (1.96e-1)" "unprognostic (3.00e-3)" "unprognostic (1.68e-2)" 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 1.6 0.0 1.4 0.0 0.1 1.1 0.1 0.0 0.1 218.8 857.1 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.3 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 32.9 0.0 7.3 0.0 0.0 0.0 0.0 17.6 0.0 0.5 0.8 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 563.8 0.0 0.0 0.1 0.0 0.0 7.3 0.2 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 4.1 108.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 CYP4A22 ENSG00000162365 "Cytochrome P450 family 4 subfamily A member 22" Q5TCH4 1 47137435-47149735 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "liver: 214.2" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 143.0" "Cancer enriched" "Detected in some" 13 "liver cancer: 20.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RH-30: 1.2" NA NA "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (5.34e-2)" "unprognostic (1.24e-1)" "unprognostic (3.19e-2)" "unprognostic (2.88e-3)" "unprognostic (2.76e-3)" "unprognostic (1.50e-3)" "unprognostic (2.21e-1)" "unprognostic (2.75e-1)" "unprognostic (1.93e-2)" "unprognostic (5.29e-3)" "unprognostic (1.02e-1)" "unprognostic (1.71e-1)" "unprognostic (8.59e-4)" 0.4 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.0 0.0 0.1 0.1 0.0 32.9 214.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 143.0 0.0 0.0 0.2 0.0 0.0 1.9 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 CYP4F2 ENSG00000186115 "Cytochrome P450 family 4 subfamily F member 2" P78329 19 15878023-15898077 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 80.2;kidney: 40.9;liver: 166.7" "Group enriched" "Detected in some" 4 "Hepatocytes: 139.7;Proximal enterocytes: 204.6" "Cancer enriched" "Detected in some" 9 "liver cancer: 29.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 19 "basophil: 8.1" "Lineage enriched" "Detected in single" 82 "granulocytes: 8.1" "Cell line enriched" "Detected in single" 4 "Hep G2: 3.8" "Low region specificity" "Detected in all" "HPA014048, HPA017265, HPA058960" Supported "Intracellular and membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA014048: AB_1847452, HPA017265: AB_1847451, HPA058960: AB_2683862" "unprognostic (7.46e-3)" "unprognostic (3.58e-1)" "unprognostic (3.01e-1)" "unprognostic (9.39e-2)" "unprognostic (1.74e-1)" "unprognostic (2.87e-2)" "unprognostic (4.55e-3)" "unprognostic (6.52e-2)" "unprognostic (2.05e-1)" "unprognostic (4.64e-2)" "unprognostic (9.82e-2)" "unprognostic (2.92e-1)" "unprognostic (8.69e-4)" "unprognostic (3.24e-1)" "unprognostic (1.89e-1)" "unprognostic (7.79e-3)" 0.0 0.0 0.1 0.1 0.1 1.1 0.2 0.1 0.3 0.1 0.5 2.2 79.9 0.0 25.8 0.2 0.0 3.3 0.0 0.2 0.1 40.9 166.7 0.0 0.1 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.1 6.6 0.9 0.0 0.0 0.1 0.0 0.8 80.2 0.0 0.3 0.1 0.6 0.5 0.1 0.0 0.0 0.0 0.0 0.3 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 3.8 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.4 0.1 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.5 4.3 0.0 0.0 0.0 0.0 0.0 12.3 1.9 0.1 5.8 0.0 0.0 0.1 1.8 5.3 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 1.4 139.7 0.0 0.0 0.0 8.9 0.0 3.8 0.0 18.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.5 204.6 37.7 0.0 0.0 0.0 0.0 0.7 0.1 0.4 0.0 0.1 0.0 0.2 0.1 5.6 0.2 CYP4F3 "CYP4F, LTB4H" ENSG00000186529 "Cytochrome P450 family 4 subfamily F member 3" Q08477 19 15640897-15662825 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 80.2;liver: 235.8" "Cell type enriched" "Detected in many" 8 "Hepatocytes: 562.4" "Cancer enhanced" "Detected in many" "liver cancer: 30.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 63 "neutrophil: 84.1" "Lineage enriched" "Detected in single" 177 "granulocytes: 84.1" "Cell line enhanced" "Detected in some" "CAPAN-2: 33.0;HaCaT: 14.9;Hep G2: 18.3;OE19: 49.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA058960 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 2: Hepatocytes - Metabolism" "HPA058960: AB_2683862" "unprognostic (1.73e-2)" "unprognostic (9.70e-3)" "unprognostic (1.21e-1)" "unprognostic (1.16e-3)" "unprognostic (5.40e-1)" "unprognostic (1.57e-1)" "unprognostic (7.15e-3)" "unprognostic (5.19e-2)" "unprognostic (2.12e-1)" "unprognostic (3.61e-2)" "unprognostic (1.26e-2)" "unprognostic (2.32e-1)" "unprognostic (1.59e-3)" "unprognostic (2.36e-1)" "unprognostic (1.12e-1)" "unprognostic (1.07e-2)" "unprognostic (2.07e-1)" 1.6 0.1 0.9 1.2 3.3 80.2 0.2 2.3 1.3 6.9 0.3 2.1 9.4 0.1 0.8 26.7 1.1 15.5 0.3 1.8 2.2 27.3 235.8 2.3 0.1 2.8 3.0 0.0 0.6 0.0 0.5 0.4 2.9 0.6 1.8 0.0 3.4 0.6 0.1 3.9 15.0 0.3 1.9 7.8 5.1 0.3 1.9 0.7 0.1 0.6 0.7 2.9 9.0 4.1 0.3 7.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 33.0 0.1 0.2 0.0 0.1 14.9 0.0 0.2 0.0 0.6 0.0 0.1 3.5 18.3 0.0 0.2 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 49.3 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.2 0.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 84.1 0.0 0.1 0.0 0.0 0.1 0.9 3.3 2.3 1.3 1.8 2.2 2.8 3.0 2.9 1.9 1.9 4.1 0.0 9.6 3.7 0.7 2.0 1.0 2.1 2.5 1.2 0.0 0.1 0.1 0.9 62.9 5.0 0.0 0.0 0.0 1.4 10.0 0.0 2.3 0.1 0.9 0.2 0.7 53.1 17.3 0.0 0.2 0.2 0.8 7.7 3.1 1.3 0.0 8.2 562.4 0.0 0.0 0.0 14.4 8.2 11.4 0.3 0.7 0.0 1.2 0.0 0.0 1.2 0.0 0.0 0.0 0.0 4.0 7.4 0.0 0.0 3.2 69.9 32.1 1.9 0.0 0.0 0.7 1.3 0.0 0.3 25.7 6.5 0.0 1.1 0.0 10.9 13.1 DAO "DAAO, DAMOX" ENSG00000110887 "D-amino acid oxidase" P14920 12 108858932-108901043 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase Schizophrenia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 71.4;kidney: 90.3;liver: 149.9" "Group enriched" "Detected in some" 8 "Hepatocytes: 46.1;Proximal tubular cells: 86.8" "Cancer enriched" "Detected in some" 9 "liver cancer: 13.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Hep G2: 1.1" "Group enriched" "Detected in some" 10 "cerebellum: 66.4;pons and medulla: 20.2" "Low region specificity" "Detected in all" "HPA038653, HPA038654" Enhanced "Intracellular and membrane" NA NA "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA038653: AB_10673016, HPA038654: AB_10673285" "unprognostic (1.50e-1)" "unprognostic (5.61e-2)" "unprognostic (1.43e-1)" "unprognostic (2.91e-1)" "unprognostic (2.18e-1)" "unprognostic (2.99e-2)" "unprognostic (2.31e-3)" "unprognostic (8.02e-2)" "unprognostic (2.88e-2)" "unprognostic (9.59e-2)" "unprognostic (9.07e-2)" "unprognostic (7.13e-2)" "prognostic favorable (4.11e-4)" "unprognostic (3.44e-3)" "unprognostic (8.96e-2)" "unprognostic (2.67e-1)" "unprognostic (2.17e-1)" 0.1 0.0 0.9 0.0 6.9 0.0 0.0 71.4 1.6 0.0 0.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 3.3 90.3 149.9 0.2 0.0 41.9 14.8 0.0 0.2 0.0 0.0 0.0 29.5 0.0 2.0 12.0 0.0 0.0 0.0 0.0 0.0 0.1 44.0 0.1 0.1 0.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 59.1 0.0 0.0 0.3 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 6.9 71.4 1.6 0.8 3.3 41.9 14.8 29.5 44.0 4.3 59.1 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.5 0.0 0.0 1.8 0.0 0.7 0.0 4.6 3.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 46.1 0.2 0.0 1.2 0.0 0.0 0.8 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.7 0.0 0.5 0.1 0.0 1.2 0.0 0.0 0.0 0.0 86.8 0.0 7.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.7 0.4 0.0 0.2 0.0 DBX2 FLJ16139 ENSG00000185610 "Developing brain homeobox 2" Q6ZNG2 12 45014672-45051099 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "brain: 9.3" "Group enriched" "Detected in some" 9 "Astrocytes: 11.4;Oligodendrocyte precursor cells: 14.1;Spermatogonia: 5.1" "Cancer enriched" "Detected in single" 32 "glioma: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065045, HPA066053" Uncertain Approved "Nucleoplasm,Nuclear membrane,Vesicles" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nuclear membrane" Vesicles "HPA065045: , HPA066053: AB_2685605" "unprognostic (1.13e-4)" "unprognostic (9.99e-2)" "unprognostic (7.82e-3)" "unprognostic (5.24e-2)" "unprognostic (5.62e-2)" "unprognostic (1.51e-1)" "unprognostic (9.22e-2)" "unprognostic (4.76e-2)" "unprognostic (1.64e-1)" "unprognostic (5.19e-1)" 0.4 0.0 3.6 0.0 4.0 0.0 0.2 3.7 3.7 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.4 3.6 0.1 0.0 0.0 0.0 8.2 4.6 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 9.3 0.0 0.0 0.6 5.2 0.0 0.2 0.2 0.0 0.0 0.1 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 4.0 3.7 3.7 3.4 3.6 8.2 4.6 5.6 9.3 5.2 7.4 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 5.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 DCN "DSPG2, SLRR1B" ENSG00000011465 Decorin P07585 12 91140484-91183217 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Corneal dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1218.7;Fibroblasts: 7960.2;Leydig cells: 6281.9;Peritubular cells: 1856.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "basophil: 24.5" "Lineage enriched" "Detected in single" 35 "granulocytes: 24.5" "Cell line enhanced" "Detected in many" "ASC diff: 3291.1;ASC TERT1: 2371.6;BJ hTERT+: 2546.6;HSkMC: 2289.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "spinal cord: 544.7" "HPA003315, CAB017118, HPA064736, CAB068930" Enhanced "Secreted to extracellular matrix" NA NA 1900000 "Cluster 46: Basophils - DNA binding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB017118: , CAB068930: AB_425394, HPA003315: AB_1078639, HPA064736: AB_2685340" "unprognostic (1.73e-1)" "unprognostic (1.90e-1)" "unprognostic (1.43e-1)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-2)" "unprognostic (2.68e-1)" "unprognostic (1.98e-1)" "unprognostic (6.12e-2)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "prognostic unfavorable (1.46e-5)" "unprognostic (3.06e-3)" "unprognostic (5.37e-2)" "unprognostic (1.59e-3)" "unprognostic (7.56e-3)" 1522.3 1171.7 60.6 272.0 80.0 4.4 2342.2 63.5 119.2 1493.0 111.6 549.9 163.5 1308.5 1302.0 932.8 1213.4 1802.7 2108.9 66.8 60.3 394.8 459.6 955.8 130.4 68.9 60.9 2681.4 257.9 80.2 112.0 1534.8 75.7 451.6 493.0 3.1 362.5 462.3 469.0 713.4 336.6 1027.8 70.2 20.0 434.5 279.6 72.8 183.0 479.3 1328.3 293.6 1895.5 783.7 57.9 0.2 0.4 4.4 0.6 3291.1 2371.6 6.2 608.7 2546.6 28.8 28.5 0.3 0.9 1.1 0.5 523.5 0.6 2.1 0.8 1.9 4.9 0.7 0.5 0.6 20.4 0.1 717.4 1.3 1.4 2289.4 8.9 78.3 38.5 12.1 1.0 0.2 0.8 0.7 63.0 0.6 1.5 10.8 1.2 0.4 1.6 0.7 2.3 2.8 3.4 0.5 2.7 11.9 10.3 1.1 0.9 1.8 0.6 0.4 0.9 132.3 1.2 497.5 0.6 3.3 3.1 2.0 8.0 2.0 0.8 24.5 0.3 0.6 0.3 0.1 0.3 0.3 0.3 0.2 0.1 0.6 0.4 0.4 2.7 0.4 0.2 0.7 0.2 0.0 60.6 80.0 63.5 119.2 66.8 60.3 68.9 60.9 75.7 70.2 72.8 57.9 351.1 41.7 44.1 2.3 4.1 609.1 5.4 0.0 264.6 1.9 25.5 31.5 154.7 10.0 11.8 20.2 0.0 31.2 12.8 0.0 1.9 1.0 25.0 39.4 1218.7 158.7 0.0 2.7 0.8 0.0 30.0 7960.2 54.0 22.0 21.5 0.2 214.9 1.4 58.8 0.0 17.1 0.1 0.0 2.8 962.7 103.0 6281.9 52.5 606.5 122.7 0.0 3.3 0.0 0.0 1.4 2.7 0.5 1856.9 23.2 5.8 0.0 0.4 5.8 0.7 210.4 236.8 408.2 13.4 9.2 36.8 482.5 63.9 72.3 70.2 0.0 10.7 DCSTAMP "DC-STAMP, FIND, TM7SF4" ENSG00000164935 "Dendrocyte expressed seven transmembrane protein" Q9H295 8 104339087-104356689 "Predicted membrane proteins, Transporters" "Differentiation, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 4.5;epididymis: 2.0;lung: 3.8" "Group enriched" "Detected in some" 5 "Hofbauer cells: 7.1;Macrophages: 6.5" "Cancer enriched" "Detected in some" 46 "thyroid cancer: 45.3" "Group enriched" "Detected in some" 4 "amygdala: 4.5;basal ganglia: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-87 MG: 1.0" "Low region specificity" "Detected in many" "Not detected" "Not detected" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 4: Macrophages - Innate immune response" "unprognostic (1.11e-2)" "unprognostic (1.22e-2)" "unprognostic (8.41e-2)" "unprognostic (2.96e-2)" "unprognostic (8.48e-4)" "unprognostic (2.14e-1)" "unprognostic (5.40e-2)" "unprognostic (1.51e-2)" "unprognostic (3.08e-2)" "unprognostic (1.18e-2)" "unprognostic (5.26e-2)" "unprognostic (2.45e-1)" "unprognostic (1.61e-3)" "unprognostic (8.84e-2)" "unprognostic (1.36e-1)" "unprognostic (8.05e-2)" "unprognostic (8.34e-3)" 0.8 0.0 4.5 0.1 2.6 0.2 0.3 0.0 0.8 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.1 0.1 0.0 0.8 0.1 0.0 0.4 3.8 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 4.5 2.6 0.0 0.8 0.8 0.1 0.0 0.1 0.1 0.0 0.8 0.1 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 7.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DCXR "DCR, HCR2, KIDCR, P34H, SDR20C1" ENSG00000169738 "Dicarbonyl and L-xylulose reductase" Q7Z4W1 17 82035136-82037709 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Xylose metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "liver: 1851.6" "Cell type enhanced" "Detected in all" "Distal tubular cells: 812.0;Hepatocytes: 3510.3;Proximal tubular cells: 2919.4" "Group enriched" "Detected in all" 5 "liver cancer: 305.9;prostate cancer: 163.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 365.2;MCF7: 446.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023371, HPA023863" Enhanced Uncertain Nucleoli,Microtubules NA NA 4000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoli, Microtubules" "HPA023371: AB_1847530, HPA023863: AB_1847531" "unprognostic (3.33e-2)" "unprognostic (1.67e-3)" "unprognostic (3.75e-1)" "unprognostic (1.16e-2)" "unprognostic (1.19e-1)" "unprognostic (8.43e-2)" "unprognostic (4.54e-3)" "unprognostic (1.86e-2)" "unprognostic (3.05e-1)" "unprognostic (2.56e-2)" "prognostic favorable (4.70e-4)" "unprognostic (1.72e-1)" "prognostic favorable (2.13e-4)" "unprognostic (1.81e-1)" "unprognostic (1.36e-1)" "unprognostic (2.64e-1)" "unprognostic (1.10e-2)" 106.7 43.9 93.1 15.2 95.3 25.3 107.6 102.5 111.1 52.0 84.4 49.6 29.2 39.5 281.3 96.6 59.2 10.8 132.7 87.6 100.7 239.9 1851.6 61.0 16.6 102.4 98.0 70.0 71.6 46.1 63.9 20.2 105.9 138.0 20.9 9.7 103.4 33.6 187.3 87.6 44.4 10.4 91.8 35.8 167.0 44.8 105.9 26.1 60.7 80.6 19.6 48.9 62.1 94.9 50.3 68.2 32.8 56.4 123.2 31.8 80.4 25.0 33.9 68.5 48.4 122.0 21.3 100.3 47.4 35.9 9.4 57.4 59.6 52.6 24.1 21.4 145.9 96.9 48.8 365.2 143.2 75.6 114.5 44.6 62.2 22.7 79.8 16.0 41.1 61.1 112.4 76.3 36.5 446.2 63.7 184.1 35.0 242.9 71.3 57.9 42.0 135.3 53.3 71.9 85.5 51.0 35.5 287.5 46.0 19.7 213.4 74.5 20.5 36.6 45.0 48.9 48.2 73.7 56.2 50.2 31.4 83.0 26.7 49.5 92.6 77.9 66.5 92.0 64.1 86.8 83.0 64.7 151.3 99.2 117.7 85.4 47.2 108.9 88.1 121.6 98.9 110.1 93.1 95.3 102.5 111.1 87.6 100.7 102.4 98.0 105.9 91.8 105.9 94.9 29.0 51.3 198.2 16.6 133.6 58.5 200.3 113.5 109.8 16.0 301.8 269.2 120.7 183.0 123.4 178.4 18.8 372.1 116.6 152.9 812.0 41.4 6.0 67.0 50.9 44.6 54.7 335.7 4.7 42.6 450.6 65.0 151.4 102.3 64.7 62.7 138.5 3510.3 164.7 21.9 9.0 170.4 189.2 165.7 65.6 22.6 70.8 82.3 179.7 1.9 52.8 145.1 78.2 5.5 10.5 30.4 135.7 47.4 98.6 215.2 158.9 2919.4 55.4 26.5 19.7 40.6 79.6 10.3 48.2 219.9 73.2 342.6 135.7 118.6 154.6 178.8 DDC AADC ENSG00000132437 "Dopa decarboxylase" P20711 7 50458436-50565405 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine biosynthesis" "Decarboxylase, Lyase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 165.8;kidney: 314.9;retina: 175.6" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 410.3;Proximal enterocytes: 391.5;Proximal tubular cells: 429.5;Rod photoreceptor cells: 498.9" "Group enriched" "Detected in many" 5 "colorectal cancer: 23.5;liver cancer: 13.4;pancreatic cancer: 6.4;renal cancer: 18.7;stomach cancer: 9.9" "Group enriched" "Detected in many" 9 "midbrain: 86.3;pons: 29.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "CACO-2: 54.5;Hep G2: 49.3;OE19: 83.6;SCLC-21H: 130.9;SH-SY5Y: 135.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "midbrain: 74.5;pons: 29.4" HPA017742 Enhanced Approved "Actin filaments" NA NA 120000 "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Actin filaments" "HPA017742: AB_1847832" "unprognostic (1.04e-1)" "unprognostic (3.68e-2)" "unprognostic (2.57e-2)" "unprognostic (3.49e-5)" "unprognostic (1.17e-1)" "unprognostic (1.03e-1)" "unprognostic (1.28e-1)" "unprognostic (5.15e-2)" "unprognostic (4.69e-2)" "unprognostic (5.44e-2)" "unprognostic (9.36e-3)" "unprognostic (5.24e-2)" "unprognostic (1.76e-3)" "unprognostic (1.60e-1)" "unprognostic (3.55e-1)" "unprognostic (7.65e-2)" "unprognostic (1.16e-1)" 0.5 48.9 0.1 2.3 0.7 0.0 1.0 0.0 0.6 0.0 0.2 36.5 154.8 0.0 9.1 0.1 0.0 0.1 0.0 0.2 2.2 314.9 54.6 2.0 0.1 6.1 86.3 0.8 15.8 0.0 0.0 0.0 29.4 0.6 37.5 175.6 0.0 0.0 0.0 0.1 165.8 1.7 0.0 0.1 18.1 1.5 1.9 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 1.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 54.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.3 0.0 0.0 11.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 83.6 0.0 0.0 0.0 0.7 1.3 0.0 130.9 135.9 0.0 4.4 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.6 0.2 2.2 6.1 86.3 29.4 0.0 1.9 0.2 0.0 0.0 12.2 0.0 2.5 0.0 0.0 0.0 0.0 89.3 0.1 0.1 0.4 2.8 0.6 3.7 41.7 0.0 0.0 34.4 25.4 0.1 6.6 0.1 0.0 1.8 410.3 0.0 0.3 0.9 0.1 0.1 0.0 0.4 0.0 0.0 1.1 67.2 0.1 3.3 0.4 67.8 0.0 1.3 0.0 5.4 0.0 2.5 0.0 0.0 0.0 45.1 0.0 0.0 0.1 0.2 31.8 0.0 0.0 0.3 391.5 429.5 0.0 498.9 0.0 0.0 0.0 4.0 0.4 0.0 0.0 0.1 1.3 0.1 88.7 0.2 DDO ENSG00000203797 "D-aspartate oxidase" Q99489 6 110391771-110415575 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 18.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 17.4;Muller glia cells: 8.2;Oligodendrocytes: 13.3;Paneth cells: 8.5;Proximal enterocytes: 8.5;Proximal tubular cells: 12.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 3.3;myeloid DC: 4.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "GAMG: 11.5;RPMI-8226: 15.9;U-937: 17.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037525, HPA037526" Enhanced Enhanced Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "HPA037525: AB_2675523, HPA037526: AB_10672352" "unprognostic (1.37e-1)" "unprognostic (1.54e-1)" "unprognostic (6.51e-2)" "unprognostic (1.30e-2)" "unprognostic (2.00e-1)" "unprognostic (3.28e-2)" "unprognostic (3.71e-2)" "unprognostic (1.01e-2)" "unprognostic (2.05e-1)" "unprognostic (2.91e-1)" "unprognostic (6.97e-2)" "unprognostic (1.43e-1)" "prognostic favorable (8.69e-5)" "unprognostic (3.51e-4)" "unprognostic (3.36e-3)" "unprognostic (1.27e-3)" "unprognostic (9.06e-2)" 1.9 8.2 4.5 0.8 7.0 1.4 2.5 5.0 4.8 1.9 4.3 2.3 7.4 2.1 2.7 0.8 4.9 2.9 18.4 4.4 4.5 10.6 11.1 3.2 1.0 5.4 4.9 0.3 2.6 5.3 1.2 1.6 5.3 2.0 3.2 2.4 4.2 2.3 10.9 0.4 7.0 2.2 4.8 2.1 1.1 0.1 4.7 0.4 1.3 7.4 0.2 1.6 0.9 5.9 0.2 0.0 0.0 0.1 0.0 0.2 1.1 0.1 5.4 1.3 0.9 0.0 0.1 0.0 0.7 0.7 11.5 0.0 0.0 0.0 2.3 5.0 0.0 5.1 0.1 4.3 1.6 0.0 0.0 0.1 0.0 2.7 0.1 2.3 0.0 0.0 0.0 1.9 4.5 0.0 0.0 0.2 0.0 0.0 0.1 0.1 3.0 15.9 0.0 4.9 0.1 0.2 0.0 0.5 0.6 0.0 0.7 1.1 0.9 1.0 0.1 0.0 2.6 0.1 0.4 0.0 2.0 17.4 0.0 0.0 2.9 0.0 0.0 3.3 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 1.1 1.0 0.0 0.0 1.1 4.5 7.0 5.0 4.8 4.4 4.5 5.4 4.9 5.3 4.8 4.7 5.9 1.1 0.0 0.0 4.9 0.0 0.0 0.7 0.7 0.6 0.0 1.4 1.1 17.4 0.0 0.4 0.0 2.1 0.2 0.1 1.8 3.9 4.5 0.3 3.6 0.5 0.7 4.2 0.0 0.0 2.2 0.2 0.6 0.0 0.9 0.0 0.1 2.5 4.9 1.7 0.0 0.1 6.0 0.0 3.1 0.4 0.0 0.3 1.6 0.0 0.0 2.0 8.2 0.0 3.5 13.3 0.8 8.5 0.0 0.0 0.4 8.5 12.9 2.2 0.2 0.0 2.1 1.2 0.0 0.0 0.2 0.0 0.0 0.2 0.3 5.0 0.5 DEPDC7 ENSG00000121690 "DEP domain containing 7" Q96QD5 11 33015876-33033582 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 29.0;kidney: 19.6;liver: 74.0;testis: 28.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 34.8;Early spermatids: 153.3;Extravillous trophoblasts: 47.0;Proximal enterocytes: 33.2;Spermatocytes: 42.3" "Cancer enhanced" "Detected in many" "liver cancer: 6.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 6.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 53.7;RH-30: 40.1;SiHa: 37.3;SK-MEL-30: 34.4;U-2197: 34.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA015800 Approved Nucleoplasm,Nucleoli,Cytosol Yes No "Cluster 2: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoli "Nucleoplasm, Cytosol" "HPA015800: AB_1847610" "unprognostic (2.34e-1)" "unprognostic (5.57e-2)" "unprognostic (1.27e-1)" "unprognostic (2.27e-1)" "unprognostic (2.66e-2)" "unprognostic (7.26e-2)" "prognostic favorable (7.26e-4)" "unprognostic (1.80e-1)" "unprognostic (1.22e-1)" "unprognostic (2.92e-1)" "unprognostic (1.17e-3)" "unprognostic (8.99e-2)" "unprognostic (1.89e-2)" "unprognostic (9.30e-2)" "unprognostic (8.09e-3)" "unprognostic (2.64e-1)" "unprognostic (2.94e-2)" 0.6 0.8 2.5 1.9 3.2 1.8 0.9 2.9 3.7 2.8 2.7 4.6 24.6 1.0 2.2 4.4 0.9 4.4 1.1 2.6 2.7 19.6 74.0 0.9 0.7 3.2 2.7 1.6 3.8 2.3 0.8 1.5 3.0 1.9 5.1 0.1 2.0 1.5 4.9 6.0 29.0 1.7 2.8 0.3 3.0 28.2 2.7 2.9 0.5 0.9 1.5 1.2 3.4 4.9 9.4 5.2 7.3 3.3 3.8 3.6 4.9 16.2 5.4 9.8 13.0 13.5 0.9 0.0 3.7 16.2 4.5 9.4 10.8 3.8 11.5 0.0 14.9 2.5 16.1 19.3 3.2 9.1 10.9 4.6 5.7 5.7 4.2 5.3 0.0 0.0 6.2 0.0 53.7 1.0 0.0 14.6 4.8 7.7 0.0 0.0 40.1 0.1 3.2 1.3 1.6 4.2 37.3 6.6 34.4 5.1 1.7 4.7 0.0 6.3 10.4 34.1 10.6 0.0 0.0 0.1 2.3 0.0 31.5 4.1 0.5 6.7 0.2 0.1 0.0 0.0 0.4 0.2 3.2 0.0 1.9 2.1 0.0 2.4 0.0 1.2 0.0 0.4 2.5 3.2 2.9 3.7 2.6 2.7 3.2 2.7 3.0 2.8 2.7 4.9 0.2 0.0 0.0 1.0 0.0 34.8 12.8 4.5 12.5 0.0 0.2 0.6 0.1 1.5 0.9 0.0 0.0 0.5 0.5 6.0 3.9 0.9 153.3 0.2 0.2 0.3 3.5 3.2 0.1 0.6 47.0 1.6 0.0 0.1 2.5 0.1 1.4 22.6 3.1 0.0 0.4 2.4 0.0 0.6 9.5 16.3 1.5 1.7 1.8 3.7 1.2 0.0 0.0 3.5 10.4 0.8 0.6 1.2 0.1 2.4 33.2 18.4 0.9 0.0 0.0 4.5 1.4 42.3 6.5 6.6 7.4 1.5 0.7 0.2 2.4 1.6 DHDH HUM2DD ENSG00000104808 "Dihydrodiol dehydrogenase" Q9UQ10 19 48933699-48944969 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 17.3;kidney: 18.0" "Group enriched" "Detected in many" 11 "Proximal enterocytes: 213.7;Proximal tubular cells: 77.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.2" "Group enriched" "Detected in many" 33 "granulocytes: 4.2;T-cells: 2.3" "Cell line enhanced" "Detected in some" "JURKAT: 3.2;U-266/70: 3.2;U-266/84: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044131 Approved Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Actin filaments" "HPA044131: AB_10966968" "unprognostic (1.54e-1)" "unprognostic (2.72e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (9.91e-4)" "unprognostic (3.33e-3)" "unprognostic (1.45e-1)" "unprognostic (5.81e-6)" "unprognostic (1.56e-2)" "unprognostic (5.88e-2)" "unprognostic (4.96e-2)" "unprognostic (3.30e-2)" "unprognostic (5.08e-2)" "prognostic favorable (3.15e-4)" "unprognostic (2.93e-2)" "unprognostic (1.23e-1)" "unprognostic (1.67e-1)" "unprognostic (1.54e-1)" 0.2 0.4 1.6 0.0 1.6 0.1 0.2 1.9 3.3 0.3 1.0 0.3 10.5 0.1 0.0 0.8 0.3 0.2 0.1 1.7 1.7 18.0 0.4 1.1 0.2 1.2 1.3 0.6 0.4 0.5 1.8 1.3 1.2 3.2 0.0 1.7 0.4 0.1 0.2 0.2 17.3 0.0 1.3 1.7 0.7 1.9 2.7 0.1 0.1 0.0 0.2 0.3 0.4 1.6 1.4 0.0 0.1 0.7 0.4 0.3 0.5 0.0 0.2 0.2 0.7 1.4 1.1 0.0 0.2 0.0 0.9 0.4 0.5 1.0 0.4 0.5 1.1 2.0 0.5 0.5 0.0 0.0 0.4 0.2 0.1 0.5 0.0 0.3 0.0 3.2 0.7 0.2 0.0 0.3 0.0 0.1 0.3 2.1 0.9 0.7 0.1 1.0 0.1 0.4 2.1 1.1 0.2 0.1 0.5 0.1 1.0 0.0 0.0 0.0 0.8 0.3 0.0 3.2 2.8 0.8 0.7 0.0 0.2 4.2 0.0 0.5 0.7 0.0 0.4 0.0 0.8 0.3 0.0 0.0 2.3 1.5 0.0 0.0 0.0 0.0 0.6 0.2 1.6 1.6 1.9 3.3 1.7 1.7 1.2 1.3 1.2 1.3 2.7 1.6 0.5 3.2 6.4 1.0 1.0 0.8 2.4 3.3 2.2 2.4 1.0 3.4 0.7 1.5 4.6 3.7 0.0 0.2 0.4 1.5 9.8 2.2 0.7 0.3 0.5 0.8 0.0 0.4 1.0 0.4 0.2 0.5 4.1 0.8 1.3 0.1 0.0 0.0 12.9 0.0 1.2 5.0 2.0 0.8 0.0 2.4 0.0 1.7 0.0 0.0 0.0 1.6 0.0 0.0 0.5 1.5 3.6 0.0 0.0 3.5 213.7 77.8 0.5 4.5 0.0 1.2 0.4 0.0 0.8 3.1 0.1 0.1 0.6 0.4 2.7 3.2 DHRS4 "FLJ11008, humNRDR, SCAD-SRL, SDR-SRL, SDR25C2" ENSG00000157326 "Dehydrogenase/reductase 4" Q9BTZ2 14 23953734-23969279 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 235.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA023972 Uncertain Approved "Nuclear membrane,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "Nuclear membrane" "HPA023972: AB_1854890" "unprognostic (1.21e-2)" "unprognostic (2.59e-1)" "unprognostic (3.46e-2)" "unprognostic (3.79e-3)" "unprognostic (1.97e-1)" "unprognostic (1.66e-1)" "unprognostic (7.35e-3)" "unprognostic (1.61e-3)" "unprognostic (2.66e-1)" "unprognostic (1.19e-2)" "unprognostic (1.06e-2)" "unprognostic (7.65e-2)" "prognostic favorable (4.55e-6)" "unprognostic (2.03e-2)" "unprognostic (1.48e-1)" "unprognostic (2.03e-1)" "unprognostic (5.68e-2)" 34.1 45.8 8.6 10.4 9.2 6.9 34.5 8.8 9.7 30.5 10.1 43.5 34.0 27.1 5.2 45.8 23.6 5.9 49.1 8.3 8.6 92.0 109.7 28.0 10.2 9.2 8.6 33.0 40.3 8.8 19.3 5.3 9.2 31.9 13.5 3.9 31.2 8.4 62.2 44.7 38.6 8.3 8.6 32.2 33.7 37.9 9.0 9.6 25.4 14.0 8.5 30.5 33.1 9.5 15.1 29.6 10.4 17.2 16.6 18.5 0.1 27.4 15.3 11.5 9.1 6.5 16.5 13.3 14.3 14.6 7.6 18.1 8.6 12.3 10.1 34.6 16.5 7.8 23.5 36.6 9.5 11.6 45.2 18.0 14.8 9.2 20.8 12.3 14.4 19.6 11.8 30.4 15.8 52.3 21.1 10.7 9.9 18.9 30.3 33.8 18.0 41.4 12.1 17.1 19.9 16.1 27.7 17.6 13.8 6.8 16.0 14.6 25.5 13.3 13.8 13.9 9.0 22.8 22.8 3.5 11.8 12.6 13.6 5.4 54.4 6.0 18.0 45.8 21.4 21.5 20.3 18.2 47.4 18.5 20.1 19.5 2.3 18.1 25.5 39.4 19.4 36.2 8.6 9.2 8.8 9.7 8.3 8.6 9.2 8.6 9.2 8.6 9.0 9.5 16.6 16.0 30.5 6.2 12.5 12.5 10.4 15.7 55.2 5.1 22.2 31.9 35.4 17.2 21.3 14.7 0.0 9.6 17.8 34.2 78.2 6.4 50.4 13.1 11.6 14.6 19.2 20.8 2.6 9.8 6.0 23.7 34.7 7.8 13.9 10.5 20.0 68.1 30.4 6.7 2.1 50.1 8.2 29.2 13.5 66.1 11.1 35.9 5.4 3.7 33.2 18.1 47.4 4.0 5.0 5.3 22.3 17.3 24.6 11.2 51.8 235.4 23.2 1.8 6.6 13.5 18.1 59.4 1.9 61.6 13.4 3.8 18.1 22.9 71.8 9.0 DHRS4L2 SDR25C3 ENSG00000187630 "Dehydrogenase/reductase 4 like 2" Q6PKH6 14 23969874-24006408 "Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 136.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 204.2;Proximal enterocytes: 326.4;Proximal tubular cells: 581.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA023972 Uncertain Approved "Nuclear membrane,Vesicles" "Secreted - unknown location" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "Nuclear membrane" "HPA023972: AB_1854890" "unprognostic (1.41e-2)" "unprognostic (2.83e-3)" "unprognostic (1.25e-1)" "unprognostic (2.68e-2)" "unprognostic (1.47e-1)" "unprognostic (2.53e-1)" "unprognostic (6.02e-2)" "unprognostic (3.97e-3)" "unprognostic (7.34e-2)" "prognostic favorable (3.21e-4)" "unprognostic (1.57e-2)" "unprognostic (1.46e-2)" "unprognostic (1.36e-3)" "unprognostic (6.00e-2)" "unprognostic (2.38e-1)" "unprognostic (2.00e-1)" "unprognostic (3.65e-2)" 27.2 39.5 28.8 14.6 29.6 11.5 30.5 28.3 38.4 26.9 30.8 34.7 34.4 19.7 12.8 38.4 18.6 10.6 45.9 28.5 27.8 122.5 136.2 22.5 14.6 29.3 28.7 25.2 34.0 24.5 16.7 10.0 28.7 32.5 26.6 6.7 24.7 20.7 50.7 37.1 42.0 18.4 28.6 29.3 27.9 41.4 29.4 16.9 21.5 28.5 16.5 26.0 26.1 29.9 18.7 29.0 4.9 24.4 46.2 47.9 0.6 17.3 34.3 24.8 18.4 8.4 22.5 12.6 11.5 35.3 16.0 20.6 22.3 29.1 20.6 43.3 13.3 3.1 24.8 52.4 34.0 15.3 47.9 50.0 36.4 16.3 23.7 17.0 29.5 40.0 10.1 44.9 26.7 61.5 40.4 16.5 9.7 45.9 31.8 64.9 19.9 38.2 35.6 23.7 26.0 15.7 24.5 21.5 15.0 10.3 25.2 24.5 20.8 12.9 13.4 15.4 8.8 25.5 21.1 3.8 11.1 23.7 18.8 4.8 56.3 6.9 19.4 47.2 20.1 21.9 20.9 22.2 45.4 17.4 21.0 19.1 2.6 17.2 29.3 37.4 21.8 33.6 28.8 29.6 28.3 38.4 28.5 27.8 29.3 28.7 28.7 28.6 29.4 29.9 39.3 16.0 29.6 10.4 17.8 27.8 46.1 56.8 27.9 9.9 45.5 54.4 17.2 47.1 34.3 25.8 2.1 21.2 22.9 37.9 127.2 40.0 20.7 20.6 20.1 32.0 37.3 24.2 7.3 55.7 7.3 36.4 13.3 16.5 17.7 31.8 50.0 204.2 146.1 11.8 6.7 61.7 42.7 55.9 42.8 35.4 43.8 41.9 51.6 10.3 65.0 79.5 35.0 10.1 8.5 30.4 54.9 37.2 10.8 32.5 326.4 581.7 28.6 8.3 32.9 24.2 32.7 17.2 1.7 42.1 40.2 13.0 21.3 37.5 78.1 42.4 DIO1 TXDI1 ENSG00000211452 "Iodothyronine deiodinase 1" P49895 1 53891239-53911086 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Thyroid hormones biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 42 "kidney: 144.9;liver: 185.3;thyroid gland: 260.2" "Group enriched" "Detected in some" 5 "Hepatocytes: 61.5;Proximal tubular cells: 115.7" "Group enriched" "Detected in many" 8 "liver cancer: 44.7;thyroid cancer: 43.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 26 "Hep G2: 33.9;SK-BR-3: 79.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (4.89e-2)" "unprognostic (4.86e-2)" "unprognostic (1.81e-2)" "unprognostic (1.21e-2)" "unprognostic (1.06e-1)" "unprognostic (2.68e-2)" "unprognostic (3.91e-3)" "unprognostic (6.96e-4)" "unprognostic (6.94e-2)" "unprognostic (4.83e-2)" "unprognostic (8.81e-2)" "unprognostic (1.43e-1)" "unprognostic (3.50e-3)" "unprognostic (9.99e-3)" "unprognostic (3.78e-2)" "prognostic unfavorable (5.44e-4)" "unprognostic (3.59e-2)" 0.1 0.2 0.2 0.1 0.1 0.1 0.7 0.1 0.2 0.1 0.2 0.1 0.1 0.2 0.0 0.2 4.6 1.0 0.6 0.1 0.1 144.9 185.3 0.4 0.8 0.3 0.2 0.2 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.3 0.7 0.3 0.0 260.2 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 1.0 0.3 0.0 33.9 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.2 0.0 0.3 0.1 0.1 0.2 0.3 0.1 0.5 0.3 0.0 0.0 0.0 0.0 0.2 0.0 79.0 0.0 0.1 2.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 0.1 0.1 0.3 0.2 0.3 0.0 0.3 0.4 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.8 0.0 0.0 0.9 0.1 15.2 11.5 0.4 0.0 0.0 0.5 0.1 0.0 11.7 0.0 3.6 0.3 0.1 0.4 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.4 61.5 0.5 0.0 0.5 0.0 0.0 2.2 0.0 5.3 0.0 0.7 0.0 1.0 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.2 0.0 115.7 10.2 0.0 0.0 0.0 0.4 0.6 0.2 0.0 0.0 2.3 0.3 0.1 0.0 0.0 DKK3 "REIC, RIG" ENSG00000050165 "Dickkopf WNT signaling pathway inhibitor 3" Q9UBP4 11 11956207-12009769 "Plasma proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1224.0" "Group enriched" "Detected in many" 7 "Cardiomyocytes: 884.3;Muller glia cells: 1960.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 6.2;memory CD8 T-cell: 3.8" "Lineage enriched" "Detected in single" 62 "T-cells: 6.2" "Cell line enhanced" "Detected in many" "BJ: 418.9;BJ hTERT+: 643.0;fHDF/TERT166: 614.4;hTERT-RPE1: 370.2;TIME: 349.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011868, CAB024949" Approved Supported "Nuclear bodies,Vesicles,Cytosol" "Secreted in other tissues" No No 18000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Nuclear bodies, Cytosol" "CAB024949: , HPA011868: AB_1847716" "unprognostic (4.24e-2)" "unprognostic (6.40e-2)" "unprognostic (1.96e-1)" "unprognostic (7.84e-2)" "unprognostic (3.06e-3)" "unprognostic (6.58e-3)" "unprognostic (1.14e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-3)" "unprognostic (5.28e-2)" "unprognostic (4.51e-2)" "unprognostic (3.87e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (7.41e-3)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.02e-3)" 31.2 79.1 110.7 10.0 183.6 0.2 26.0 12.6 135.2 89.7 104.8 53.2 14.6 47.0 16.7 29.7 23.0 67.0 1224.0 147.7 80.2 17.0 5.6 123.7 8.5 95.1 54.3 38.1 18.2 34.2 38.2 25.0 46.8 59.4 13.0 204.1 30.9 78.1 7.8 29.7 24.6 43.1 83.9 33.2 31.7 30.9 99.9 4.7 16.4 18.8 5.4 40.9 48.3 121.6 1.5 13.1 18.1 0.1 15.3 29.7 0.6 418.9 643.0 182.4 205.5 9.6 3.2 0.0 44.8 614.4 96.8 64.4 1.5 181.9 69.5 0.1 0.5 0.0 1.7 0.0 113.6 0.0 0.3 45.3 60.0 61.9 151.3 370.2 195.3 0.0 0.2 0.4 256.4 0.0 0.1 0.4 8.6 0.0 0.5 0.1 1.2 0.1 62.5 0.6 0.5 53.2 2.0 0.0 0.2 47.9 0.2 0.5 349.7 107.5 82.8 11.2 110.3 0.1 0.0 0.3 18.1 0.0 103.5 0.0 0.0 0.0 0.5 0.0 6.2 0.0 0.6 3.8 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 110.7 183.6 12.6 135.2 147.7 80.2 95.1 54.3 46.8 83.9 99.9 121.6 5.8 3.2 3.0 94.3 0.1 45.6 59.5 70.3 93.4 31.6 3.2 103.2 884.3 0.0 12.8 0.0 12.5 0.5 0.4 0.0 0.0 0.8 104.3 0.7 8.4 32.9 1.8 0.0 90.4 0.2 0.8 106.1 7.1 0.6 1.3 17.0 66.8 0.4 20.4 13.5 83.7 0.1 0.0 1.3 12.5 88.5 20.5 1.4 64.0 38.4 0.0 1960.4 0.0 27.6 14.7 1.1 0.1 57.6 1.7 32.8 0.0 0.2 2.9 67.5 190.7 12.7 83.4 1.2 3.2 5.8 14.8 0.8 4.1 0.5 0.3 3.0 DLGAP2 "C8orf68, DAP-2, ERICH1-AS1" ENSG00000198010 "DLG associated protein 2" Q9P1A6 8 737628-1708476 "Nuclear receptors, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.9;pituitary gland: 2.6;testis: 12.2" "Group enriched" "Detected in some" 8 "Excitatory neurons: 645.0;Inhibitory neurons: 467.8" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebral cortex: 3.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA030320 Uncertain NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA030320: AB_10600904" "unprognostic (8.86e-2)" "unprognostic (2.32e-1)" "unprognostic (5.32e-1)" "unprognostic (1.33e-1)" "unprognostic (5.42e-2)" "unprognostic (1.23e-3)" "unprognostic (1.07e-1)" "unprognostic (2.71e-2)" "unprognostic (5.01e-2)" "unprognostic (2.16e-2)" "unprognostic (1.90e-3)" "unprognostic (2.53e-1)" "unprognostic (1.04e-1)" "unprognostic (2.05e-3)" "unprognostic (1.96e-1)" "unprognostic (3.85e-1)" "unprognostic (3.81e-1)" 0.2 0.0 0.1 0.0 1.0 0.0 0.1 0.0 3.9 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 12.2 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 3.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 16.0 0.0 0.4 0.3 0.0 0.0 4.1 0.7 0.9 1.7 0.0 1.8 0.0 16.7 0.0 0.0 0.0 1.9 0.1 64.1 0.1 0.0 0.6 0.0 0.0 645.0 0.0 0.0 1.2 0.0 0.1 0.0 0.2 0.0 0.0 0.1 40.4 467.8 0.0 0.0 0.0 0.3 31.9 0.9 0.2 1.8 35.6 0.0 1.9 0.0 12.1 9.1 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.7 2.5 0.0 0.3 0.2 8.2 6.2 0.0 0.1 0.0 0.1 0.2 0.0 0.1 DLL4 ENSG00000128917 "Delta like canonical Notch ligand 4" Q9NR61 15 40929340-40939073 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Angiogenesis, Differentiation, Neurogenesis, Notch signaling pathway, Sensory transduction, Vision" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 70.7;Distal enterocytes: 24.2;Endothelial cells: 48.6;Hepatic stellate cells: 30.4;Intestinal goblet cells: 36.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "BJ hTERT+: 59.4;HUVEC TERT2: 15.7;SCLC-21H: 32.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023392 Uncertain NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA023392: AB_1847740" "unprognostic (1.92e-2)" "prognostic unfavorable (3.97e-4)" "unprognostic (7.52e-2)" "unprognostic (4.71e-2)" "unprognostic (2.72e-1)" "unprognostic (4.16e-2)" "unprognostic (3.56e-2)" "unprognostic (1.60e-2)" "unprognostic (2.49e-1)" "unprognostic (2.73e-1)" "unprognostic (3.51e-2)" "unprognostic (6.10e-2)" "unprognostic (2.56e-3)" "unprognostic (9.92e-2)" "unprognostic (2.93e-1)" "unprognostic (1.51e-2)" "unprognostic (5.51e-3)" 25.2 2.6 6.9 2.9 6.1 0.3 21.2 6.5 7.0 8.0 4.9 7.6 4.0 8.8 1.0 3.7 7.6 3.7 23.8 5.8 6.0 10.0 3.5 22.5 5.0 7.1 6.5 4.1 2.9 2.9 5.6 19.8 7.5 7.9 3.0 0.9 4.3 2.7 10.0 5.5 6.8 4.2 6.6 4.6 4.8 1.5 8.4 5.0 15.4 10.6 1.7 8.7 7.6 6.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.9 59.4 0.2 0.3 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.8 0.0 0.1 0.0 1.0 0.5 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 15.7 0.0 0.4 1.1 0.1 0.1 0.0 0.6 0.0 0.9 0.0 1.4 0.5 1.6 0.0 0.1 32.5 0.0 0.3 0.7 0.0 0.0 0.0 3.5 0.9 0.0 0.1 0.0 0.0 1.3 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 6.1 6.5 7.0 5.8 6.0 7.1 6.5 7.5 6.6 8.4 6.2 70.7 0.0 2.7 0.0 1.7 1.3 0.2 0.2 4.0 4.9 1.6 2.8 3.2 1.5 0.9 0.0 0.0 1.5 0.2 24.2 0.0 0.2 0.2 1.9 0.7 48.6 17.4 0.0 0.9 0.2 0.6 3.1 13.3 2.6 2.5 0.0 30.4 0.1 0.2 0.0 0.6 36.3 6.1 1.6 0.8 0.3 0.0 0.8 1.8 11.2 0.0 0.2 0.0 0.5 0.5 0.2 16.7 0.0 3.5 2.3 9.2 0.0 0.2 1.4 0.0 0.9 3.8 0.8 2.0 1.0 1.6 1.9 0.4 0.4 12.0 0.6 DMGDH ENSG00000132837 "Dimethylglycine dehydrogenase" Q9UI17 5 78997564-79236038 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 18 "kidney: 169.4;liver: 283.8" "Cell type enhanced" "Detected in many" "Early spermatids: 40.6;Hepatocytes: 104.2;Late spermatids: 33.1;Proximal tubular cells: 83.9" "Group enriched" "Detected in some" 12 "liver cancer: 15.6;renal cancer: 12.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 3.6;Hep G2: 7.6;hTEC/SVTERT24-B: 2.2;Karpas-707: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036441, HPA036442, HPA077849" Enhanced Supported Mitochondria NA NA 680000 "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA036441: AB_2675124, HPA036442: AB_10669792, HPA077849: AB_2686859" "unprognostic (3.11e-2)" "unprognostic (3.36e-1)" "unprognostic (6.70e-2)" "unprognostic (1.81e-1)" "unprognostic (3.15e-1)" "unprognostic (2.52e-3)" "prognostic favorable (5.32e-5)" "unprognostic (2.21e-1)" "unprognostic (3.05e-2)" "unprognostic (3.19e-2)" "unprognostic (1.07e-4)" "unprognostic (1.89e-1)" "prognostic favorable (1.17e-5)" "unprognostic (2.03e-2)" "unprognostic (9.75e-4)" "unprognostic (1.46e-1)" "unprognostic (2.26e-1)" 8.4 4.5 1.5 0.3 1.7 0.0 2.2 1.4 1.6 1.4 3.0 1.3 0.2 2.8 12.2 1.4 1.3 2.1 1.9 1.5 2.4 169.4 283.8 0.4 0.2 1.5 1.9 2.2 1.8 0.6 2.9 0.1 2.0 1.8 0.4 1.5 0.4 1.8 2.4 0.6 0.6 1.7 1.4 0.1 1.0 2.3 2.9 0.3 4.8 1.5 0.3 1.2 0.5 1.6 0.0 0.0 0.0 0.3 0.3 0.8 0.3 0.2 3.6 0.8 1.4 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.0 0.0 7.6 1.9 0.0 0.0 1.7 2.1 2.2 1.6 1.5 0.0 0.8 0.0 2.3 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 2.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.7 1.4 1.6 1.5 2.4 1.5 1.9 2.0 1.4 2.9 1.6 1.3 0.0 1.1 19.9 2.9 0.1 0.5 1.0 1.8 1.9 1.4 1.8 1.0 2.8 0.8 9.2 2.1 0.3 1.9 0.7 19.6 0.4 40.6 2.6 5.0 1.2 1.2 6.1 5.8 0.7 0.1 2.7 3.6 2.7 0.0 4.1 1.8 104.2 0.1 0.0 1.5 1.2 4.1 1.6 0.4 33.1 2.5 1.7 0.0 4.7 0.2 4.3 3.1 4.5 3.3 0.8 1.4 2.6 4.5 0.9 1.6 83.9 4.7 3.7 0.0 1.7 0.7 4.9 5.3 1.8 0.3 0.3 2.9 4.4 0.9 0.8 DNMT3L MGC1090 ENSG00000142182 "DNA methyltransferase 3 like" Q9UJW3 21 44246339-44262216 "Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "liver: 1.9" "Group enriched" "Detected in some" 6 "Hepatocytes: 20.8;Proximal tubular cells: 29.1" "Cancer enriched" "Detected in some" 90 "testis cancer: 46.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "BEWO: 24.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA055234, HPA066780" Approved Approved "Nuclear speckles" NA NA "Cluster 15: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA055234: AB_2682750, HPA066780: AB_2685719" "unprognostic (1.05e-4)" "unprognostic (1.91e-1)" "unprognostic (2.73e-9)" "unprognostic (2.77e-1)" "unprognostic (5.28e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.6 1.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 24.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.7 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 20.8 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 29.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.1 DPEP1 ENSG00000015413 "Dipeptidase 1" P16444 16 89613308-89638456 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Dipeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 377.4;kidney: 255.9;pancreas: 440.7" "Cell type enhanced" "Detected in many" "Peritubular cells: 1217.5;Proximal enterocytes: 4683.5;Proximal tubular cells: 829.6" "Cancer enriched" "Detected in many" 8 "colorectal cancer: 107.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 8.5;Hep G2: 33.1;HHSteC: 13.9;U-937: 46.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009426, HPA012783" Enhanced Approved "Nucleoplasm,Cell Junctions" "Intracellular and membrane" NA NA 370000 "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Cell Junctions" "HPA009426: AB_1847842, HPA012783: AB_1847843" "unprognostic (3.31e-2)" "unprognostic (3.86e-1)" "unprognostic (1.37e-1)" "unprognostic (1.95e-2)" "unprognostic (1.91e-2)" "unprognostic (4.93e-2)" "unprognostic (1.04e-1)" "unprognostic (1.89e-1)" "unprognostic (3.45e-2)" "unprognostic (5.18e-1)" "unprognostic (8.68e-2)" "unprognostic (1.27e-1)" "prognostic favorable (6.84e-4)" "unprognostic (6.12e-3)" "unprognostic (1.92e-1)" "unprognostic (5.23e-2)" "unprognostic (3.93e-2)" 0.6 2.3 0.0 1.8 0.0 0.4 0.5 0.0 0.2 4.1 0.0 1.7 85.5 0.6 0.9 0.3 0.6 3.9 0.3 0.0 0.3 255.9 0.5 0.9 2.8 0.2 1.1 0.8 440.7 0.0 0.5 0.8 0.6 0.5 0.5 0.3 1.2 1.0 0.0 2.2 377.4 0.3 0.3 4.5 1.6 46.5 0.9 0.9 0.8 0.0 0.9 2.2 0.9 0.0 0.0 0.9 0.2 0.0 1.7 0.2 4.4 0.0 0.0 0.0 0.0 8.5 0.2 0.0 3.0 0.0 0.0 0.0 0.2 0.0 0.0 2.2 0.6 0.0 0.0 33.1 13.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 1.1 1.1 3.4 0.0 0.0 0.0 3.0 0.0 0.1 0.9 0.8 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 1.4 0.0 0.0 0.2 0.1 0.0 46.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.2 1.1 0.6 0.3 0.9 0.0 0.1 3.2 1.8 0.0 9.2 0.5 0.0 0.0 0.0 5.8 1.7 0.0 0.3 0.0 0.6 23.9 0.0 0.2 0.0 2.0 56.7 0.5 13.2 0.2 0.2 7.0 8.9 0.0 0.3 192.1 0.8 8.9 1.1 0.1 1.3 0.7 1.1 0.0 0.5 0.0 0.3 142.3 0.0 0.3 0.3 45.2 289.8 4.8 5.4 0.0 1.0 0.1 0.0 0.0 0.1 27.4 187.4 1217.5 61.2 0.0 4683.5 829.6 0.0 0.2 6.6 0.0 0.7 17.3 2.8 0.0 0.3 0.4 2.5 0.2 151.7 0.0 DPF3 "BAF45c, cer-d4, Cerd4, FLJ14079" ENSG00000205683 "Double PHD fingers 3" Q92784 14 72619296-72894116 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.5;retina: 18.0;skeletal muscle: 26.5" "Cell type enhanced" "Detected in many" "Astrocytes: 104.5;Cone photoreceptor cells: 108.4;Early spermatids: 58.5;Oligodendrocyte precursor cells: 123.1;Oligodendrocytes: 115.7;Rod photoreceptor cells: 85.5" "Cancer enhanced" "Detected in some" "glioma: 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 17.7;BJ hTERT+ SV40 Large T+: 12.2;HEL: 31.5;Karpas-707: 12.4" "Region enhanced" "Detected in all" "cerebellum: 49.5" "Low region specificity" "Detected in all" "HPA066790, HPA070601" Enhanced Enhanced Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 36: HEL - Hemostasis" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA066790: AB_2685724, HPA070601: AB_2686284" "unprognostic (2.38e-2)" "unprognostic (2.96e-1)" "unprognostic (3.25e-1)" "unprognostic (1.56e-2)" "unprognostic (1.55e-1)" "unprognostic (9.98e-2)" "unprognostic (4.80e-2)" "unprognostic (1.19e-2)" "unprognostic (1.33e-1)" "unprognostic (3.54e-2)" "unprognostic (9.71e-3)" "unprognostic (1.02e-1)" "unprognostic (2.02e-1)" "unprognostic (3.85e-3)" "unprognostic (4.08e-2)" "unprognostic (4.80e-2)" "unprognostic (1.96e-1)" 0.3 1.4 2.8 0.5 6.7 2.6 0.4 35.5 5.1 0.4 0.0 2.0 0.2 0.2 0.0 0.6 0.3 0.3 14.2 10.2 3.8 1.4 3.0 0.2 0.8 12.0 5.9 13.7 0.3 5.1 0.6 0.3 12.6 0.1 1.5 18.0 0.4 0.2 26.5 0.5 1.3 0.5 4.4 1.0 0.5 3.5 5.7 0.3 0.4 9.1 1.0 0.2 0.2 7.7 2.1 0.0 1.6 0.1 0.2 2.9 17.7 5.4 5.1 12.2 4.7 0.1 0.2 0.2 0.3 1.7 0.2 0.1 1.7 0.8 7.4 0.3 0.6 31.5 0.2 0.0 0.5 0.2 0.5 0.7 0.3 2.8 2.0 2.0 4.0 3.4 2.8 12.4 3.9 0.1 2.7 0.3 0.0 0.0 1.8 6.9 0.8 0.4 2.1 0.0 1.2 0.7 0.0 0.1 0.0 0.5 0.0 0.0 8.7 6.0 0.0 2.2 0.6 4.3 1.2 0.4 0.5 1.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 6.7 35.5 5.1 10.2 3.8 12.0 5.9 12.6 4.4 5.7 7.7 0.8 0.0 0.0 104.5 6.0 0.6 0.1 0.0 0.0 10.5 1.1 0.9 38.4 1.5 0.0 0.0 108.4 2.6 2.6 7.5 1.9 0.1 58.5 0.1 0.8 2.9 0.0 8.6 17.7 0.4 1.3 2.8 0.0 0.1 4.5 43.2 1.1 4.4 0.4 6.7 21.7 3.4 0.0 0.8 0.7 34.3 0.3 1.7 0.0 8.4 0.1 8.6 2.1 123.1 115.7 0.7 5.1 4.9 2.6 0.1 2.7 10.7 0.0 85.5 0.0 2.6 3.5 4.5 1.2 0.3 0.3 0.1 3.8 14.5 7.4 0.0 DPP6 "DPL1, DPPX" ENSG00000130226 "Dipeptidyl peptidase like 6" P42658 7 153887097-154894285 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.0;endometrium 1: 58.2" "Group enriched" "Detected in many" 4 "Excitatory neurons: 673.4;Inhibitory neurons: 1195.9;Oligodendrocyte precursor cells: 1947.8" "Cancer enriched" "Detected in some" 11 "glioma: 12.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "NTERA-2: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050509 Enhanced Supported NA NA "Cluster 42: Non-specific - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA050509: AB_2681150" "unprognostic (1.29e-1)" "unprognostic (3.55e-2)" "unprognostic (5.68e-2)" "unprognostic (5.86e-2)" "unprognostic (1.53e-2)" "unprognostic (2.28e-1)" "unprognostic (2.73e-1)" "unprognostic (5.83e-4)" "unprognostic (1.55e-1)" "unprognostic (2.98e-1)" "unprognostic (7.45e-3)" "unprognostic (4.04e-3)" "unprognostic (2.94e-3)" "unprognostic (1.85e-4)" "unprognostic (1.05e-1)" "unprognostic (4.61e-3)" "unprognostic (6.11e-2)" 0.6 8.2 16.5 0.2 24.5 0.1 0.5 32.0 34.5 5.8 0.0 19.8 0.5 58.2 2.5 0.3 5.2 0.1 0.2 42.7 21.6 5.3 0.0 1.4 0.1 54.0 24.5 0.7 3.9 0.0 10.8 0.2 53.1 0.3 1.6 11.1 0.1 8.9 6.0 3.6 3.4 19.9 8.6 4.7 7.8 7.3 32.2 1.9 17.1 0.9 0.0 0.3 1.1 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.2 11.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 1.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.6 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.3 0.2 0.2 0.1 0.1 0.0 16.5 24.5 32.0 34.5 42.7 21.6 54.0 24.5 53.1 8.6 32.2 14.8 0.1 0.0 0.0 147.9 0.0 3.3 0.4 0.0 0.0 27.0 0.4 1.3 7.4 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 13.4 0.9 21.6 0.4 10.3 0.0 673.4 4.0 0.0 2.1 0.0 0.5 0.0 0.0 0.0 0.0 0.2 32.0 1195.9 0.4 0.0 0.0 0.0 18.4 1.2 0.2 16.0 22.5 0.0 17.1 0.0 1947.8 290.8 0.3 0.0 3.8 0.0 0.1 0.1 0.4 0.8 6.1 0.0 0.7 0.9 1.2 4.0 0.0 1.6 0.0 0.2 0.0 0.0 0.2 DPYS DHPase ENSG00000147647 Dihydropyrimidinase Q14117 8 104330324-104467055 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 39 "kidney: 199.6;liver: 477.6" "Group enriched" "Detected in some" 12 "Hepatocytes: 459.5;Proximal tubular cells: 518.8" "Cancer enriched" "Detected in some" 5 "liver cancer: 57.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024785, HPA070814" Enhanced NA NA 820000 "Cluster 85: Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA024785: AB_1847856, HPA070814: " "unprognostic (1.54e-3)" "unprognostic (2.33e-1)" "unprognostic (1.47e-1)" "unprognostic (2.18e-1)" "unprognostic (2.69e-1)" "unprognostic (2.38e-3)" "unprognostic (4.16e-4)" "unprognostic (1.56e-1)" "unprognostic (3.53e-2)" "unprognostic (3.85e-3)" "unprognostic (2.43e-1)" "unprognostic (4.81e-2)" "unprognostic (9.56e-3)" "unprognostic (2.72e-1)" "unprognostic (2.02e-1)" "unprognostic (1.86e-1)" 8.6 2.8 0.6 0.1 0.6 0.0 0.4 0.2 1.7 1.2 0.2 0.2 0.0 0.1 0.6 0.1 0.7 6.5 0.1 0.6 0.5 199.6 477.6 0.6 0.3 0.5 0.7 0.2 0.1 0.6 0.2 0.6 0.6 4.4 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.3 0.1 0.9 1.2 5.1 0.0 0.0 0.0 0.2 0.1 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.2 1.7 0.6 0.5 0.5 0.7 0.6 0.3 1.2 0.5 0.1 0.0 0.0 1.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 40.0 0.0 20.2 0.0 0.0 0.0 0.0 27.4 0.1 12.8 0.3 0.1 1.0 0.0 16.0 11.2 0.0 0.0 1.8 0.0 0.3 0.0 0.4 11.7 459.5 1.4 0.0 4.6 0.0 0.0 11.1 0.3 13.5 0.9 10.6 0.0 14.0 0.4 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.7 0.0 518.8 0.0 0.1 0.0 0.0 0.0 1.2 1.7 0.0 0.0 0.0 2.7 0.0 0.0 0.0 DUSP9 "MKP-4, MKP4" ENSG00000130829 "Dual specificity phosphatase 9" Q99956 X 153642492-153651326 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "kidney: 56.9;placenta: 72.6" "Group enriched" "Detected in some" 14 "Cytotrophoblasts: 1171.5;Distal tubular cells: 727.8;Syncytiotrophoblasts: 1735.1" "Cancer enhanced" "Detected in many" "liver cancer: 10.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 9 "Hep G2: 372.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA003336 Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "HPA003336: AB_1078709" "unprognostic (4.64e-2)" "unprognostic (6.48e-2)" "unprognostic (4.87e-2)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.52e-2)" "unprognostic (2.74e-3)" "unprognostic (9.36e-3)" "unprognostic (6.15e-2)" "unprognostic (2.81e-1)" "unprognostic (3.03e-1)" "unprognostic (1.29e-2)" "unprognostic (1.38e-2)" "unprognostic (2.68e-7)" "unprognostic (4.49e-2)" "unprognostic (2.08e-1)" "unprognostic (2.77e-2)" "unprognostic (5.52e-2)" 0.2 0.0 4.1 0.0 3.3 0.0 0.2 1.7 3.8 0.1 1.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 4.0 1.9 56.9 1.1 0.0 0.0 2.1 2.5 0.8 0.5 0.7 0.0 72.6 2.2 0.1 0.0 0.0 0.5 0.3 0.0 0.1 0.1 0.0 1.9 0.0 0.0 1.6 2.8 0.0 0.0 0.0 0.0 0.7 0.1 2.6 1.6 0.8 0.1 32.6 0.0 0.0 10.3 0.1 0.0 0.0 0.0 6.5 2.0 0.0 15.8 0.0 1.2 7.5 39.9 1.0 0.0 1.1 7.3 0.0 3.0 372.7 0.0 0.0 5.6 0.0 0.5 0.0 0.0 0.0 0.0 0.2 9.7 0.0 0.0 2.1 0.1 0.8 1.1 1.8 14.8 0.0 0.0 0.0 0.1 9.4 0.4 1.2 2.3 2.8 1.6 0.9 0.6 3.9 0.2 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 3.3 1.7 3.8 4.0 1.9 2.1 2.5 2.2 1.9 2.8 2.6 0.0 0.0 0.0 3.6 0.5 0.6 1.0 0.6 2.8 0.0 0.2 3.4 2.3 1.5 0.0 11.0 0.0 1171.5 0.0 0.0 727.8 0.1 0.0 0.1 0.1 3.1 0.0 0.0 0.7 0.0 84.0 6.1 0.0 0.0 0.0 3.8 0.0 0.9 84.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.4 0.0 0.8 0.0 3.2 0.4 0.0 0.0 0.0 0.4 0.8 8.9 0.2 0.0 1735.1 0.2 10.8 0.1 1.1 EAF2 "BM040, TRAITS, U19" ENSG00000145088 "ELL associated factor 2" Q96CJ1 3 121835183-121886526 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 71.8;lymphoid tissue: 53.6" "Cell type enhanced" "Detected in many" "B-cells: 73.7;Plasma cells: 144.1;Proximal tubular cells: 128.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "memory B-cell: 104.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 73.5;HL-60: 114.9;THP-1: 59.9;U-698: 93.5;U-937: 64.0" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA008411 Enhanced NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA008411: AB_1847950" "unprognostic (3.43e-1)" "prognostic favorable (2.25e-9)" "unprognostic (1.48e-1)" "prognostic favorable (2.66e-4)" "unprognostic (1.00e-1)" "unprognostic (3.18e-2)" "unprognostic (1.89e-3)" "unprognostic (7.04e-2)" "unprognostic (2.04e-1)" "unprognostic (2.18e-1)" "unprognostic (2.08e-1)" "unprognostic (1.14e-1)" "unprognostic (2.08e-2)" "unprognostic (2.55e-1)" "unprognostic (1.81e-1)" "unprognostic (9.04e-2)" "unprognostic (8.34e-2)" 4.3 2.6 2.3 19.5 2.0 71.8 10.0 2.1 3.1 5.5 1.5 10.3 8.9 2.0 4.9 2.7 1.4 5.0 1.7 2.7 2.4 30.2 3.5 4.3 53.6 2.1 2.4 1.0 4.2 3.1 3.3 2.9 2.2 21.0 11.6 1.7 7.6 8.4 0.8 1.0 7.7 3.5 1.4 16.9 8.2 4.6 3.0 7.7 1.7 1.3 43.4 7.8 1.4 2.0 3.5 3.0 2.0 2.5 0.7 2.1 6.0 1.3 0.8 2.4 4.4 5.8 2.0 73.5 1.5 0.3 7.7 5.7 5.0 3.0 6.0 35.8 2.9 42.4 3.0 11.1 1.0 114.9 44.7 1.0 6.9 2.8 2.6 0.0 2.3 10.0 5.0 14.2 1.1 1.0 16.3 15.1 2.9 13.8 2.5 17.1 6.4 11.2 2.4 4.3 2.5 0.6 2.1 2.0 5.7 5.5 1.8 59.9 0.7 1.5 2.4 1.4 3.4 25.4 12.2 93.5 2.8 64.0 4.7 11.9 18.8 42.8 1.4 41.2 2.8 104.4 2.2 1.5 22.5 97.4 2.9 1.6 3.5 1.8 54.7 30.5 2.7 13.1 2.3 2.0 2.1 3.1 2.7 2.4 2.1 2.4 2.2 1.4 3.0 2.0 4.5 3.2 4.2 48.0 73.7 2.4 6.9 25.0 6.2 1.3 5.9 6.6 4.3 0.0 16.5 1.8 4.2 15.5 15.3 2.9 17.6 4.4 36.4 4.3 2.0 2.5 1.2 10.3 17.3 17.6 2.2 4.9 7.7 7.7 10.1 2.5 3.9 1.6 16.5 0.0 28.6 5.7 16.2 32.4 15.7 4.6 5.0 29.8 16.0 8.4 29.5 9.4 6.2 12.1 7.7 4.2 4.7 3.0 144.1 11.1 2.4 128.0 9.1 5.3 0.0 4.5 4.6 37.6 18.1 2.3 2.4 7.7 11.1 2.2 3.5 5.9 ECHDC3 FLJ20909 ENSG00000134463 "Enoyl-CoA hydratase domain containing 3" Q96DC8 10 11742366-11764070 "Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 161.6;skeletal muscle: 128.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 81.2;Distal tubular cells: 144.8;Hepatocytes: 152.0;Proximal tubular cells: 209.9" "Cancer enhanced" "Detected in all" "liver cancer: 35.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "eosinophil: 15.4" "Lineage enriched" "Detected in many" 9 "granulocytes: 15.4" "Cell line enhanced" "Detected in many" "A-431: 52.9;BEWO: 28.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA038306 Enhanced NA NA 120000 "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 28: BEWO - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA038306: AB_10672586" "unprognostic (8.74e-2)" "unprognostic (1.69e-1)" "unprognostic (2.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.92e-1)" "unprognostic (2.37e-2)" "unprognostic (1.09e-1)" "unprognostic (1.64e-1)" "unprognostic (5.07e-1)" "unprognostic (2.23e-1)" "unprognostic (2.04e-2)" "unprognostic (3.53e-1)" "prognostic favorable (3.43e-4)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (3.91e-4)" 71.7 29.3 2.6 3.2 2.4 7.0 52.8 2.5 2.5 15.9 17.5 6.7 1.8 11.0 2.2 22.9 11.1 1.8 67.0 2.6 4.3 63.0 161.6 17.5 3.7 3.0 2.7 10.5 29.7 1.8 10.8 7.9 2.9 13.7 3.6 2.0 28.6 13.7 128.4 21.7 6.0 4.4 2.9 15.7 26.6 14.3 3.8 2.8 17.9 60.1 5.5 9.3 17.8 3.3 52.9 7.6 0.1 0.0 0.0 0.0 28.7 6.3 0.0 4.6 4.0 19.1 0.4 0.0 5.8 14.1 1.3 12.5 11.9 1.9 2.0 0.1 0.5 0.0 7.6 0.0 20.5 0.0 7.4 14.1 11.8 4.8 0.0 0.4 9.3 0.0 19.6 0.0 1.4 7.3 0.0 0.2 13.3 0.1 0.0 16.3 0.0 0.0 3.6 0.0 5.5 8.4 0.0 13.1 0.0 16.5 20.5 2.6 2.8 0.0 5.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 3.6 2.9 1.7 15.4 0.0 0.6 0.0 0.2 0.1 0.5 1.7 1.7 0.3 0.0 3.6 0.5 0.7 0.6 0.0 0.3 2.6 2.4 2.5 2.5 2.6 4.3 3.0 2.7 2.9 2.9 3.8 3.3 2.7 19.2 11.8 0.0 3.6 4.5 13.8 2.7 0.0 0.9 16.7 27.2 42.2 17.2 6.4 16.5 2.1 81.2 0.1 1.3 144.8 33.6 4.0 2.3 5.9 3.5 0.0 1.7 0.3 29.8 32.9 6.0 16.3 4.6 0.0 49.5 4.6 152.0 13.1 0.0 0.2 0.6 6.1 14.1 2.2 6.3 2.8 10.6 8.8 1.0 6.8 13.1 0.0 0.0 0.5 13.6 1.2 3.4 6.4 26.1 0.9 209.9 0.4 2.7 19.7 12.0 12.0 22.1 9.6 0.4 5.7 28.9 1.5 4.9 1.9 6.8 ECHS1 SCEH ENSG00000127884 "Enoyl-CoA hydratase, short chain 1" P30084 10 133362485-133373354 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1128.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 1476.3;Proximal tubular cells: 2336.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003783, HPA021995, HPA022476" Enhanced Enhanced Mitochondria NA NA 1200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB003783: , HPA021995: AB_1847974, HPA022476: AB_1847975" "unprognostic (3.68e-1)" "unprognostic (2.46e-3)" "unprognostic (9.57e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-1)" "unprognostic (3.14e-1)" "unprognostic (2.51e-3)" "unprognostic (2.30e-1)" "unprognostic (1.82e-2)" "unprognostic (2.28e-2)" "unprognostic (1.60e-1)" "unprognostic (1.27e-1)" "prognostic favorable (8.57e-5)" "unprognostic (2.84e-2)" "unprognostic (1.19e-2)" "unprognostic (3.04e-2)" "unprognostic (2.50e-2)" 302.4 127.1 127.7 53.7 127.8 43.9 116.9 131.3 136.1 59.8 149.7 143.1 171.6 47.0 89.3 107.9 90.5 66.7 226.4 133.1 129.9 481.7 1128.7 48.5 52.4 129.4 129.9 71.3 96.8 98.7 74.3 73.6 128.8 102.0 104.6 39.8 163.4 123.2 294.3 68.2 153.6 59.4 130.3 48.4 84.5 52.6 134.6 40.0 88.5 271.6 59.0 87.4 57.8 136.0 185.1 229.2 120.4 303.4 173.0 111.4 110.5 132.2 175.9 183.2 154.1 509.5 174.0 139.2 111.9 151.4 94.4 167.7 160.2 136.1 132.0 107.4 281.2 138.5 128.1 367.2 145.0 180.4 93.5 124.5 115.9 121.2 153.6 160.8 165.1 98.3 127.8 117.4 181.6 443.9 90.7 352.0 84.4 289.8 272.1 152.8 146.4 74.6 227.8 236.0 78.1 123.4 137.0 224.1 178.9 69.4 174.8 171.5 132.1 81.3 115.9 169.9 177.4 87.0 58.8 159.8 192.4 98.8 68.7 96.1 184.7 86.8 105.5 212.2 137.6 178.7 117.8 115.8 242.6 148.9 119.3 115.8 19.8 166.0 168.1 104.9 123.0 233.0 127.7 127.8 131.3 136.1 133.1 129.9 129.4 129.9 128.8 130.3 134.6 136.0 99.2 44.8 82.7 16.3 60.5 68.2 86.9 271.8 62.6 57.0 98.5 119.6 255.2 210.1 161.5 174.7 6.2 470.2 34.0 298.6 565.4 162.8 29.9 148.9 92.7 71.4 131.7 72.2 11.6 101.1 163.5 92.5 87.7 226.4 91.2 120.0 88.5 1476.3 221.1 45.4 11.0 223.0 175.0 92.1 61.5 39.1 77.6 88.0 135.2 10.3 113.0 145.2 45.3 10.6 24.3 107.8 248.6 91.7 57.5 88.0 486.2 2336.5 93.2 55.2 85.5 57.0 98.8 52.9 66.1 125.2 76.3 299.1 62.5 220.0 317.2 127.8 ECSCR "ARIA, ECSM2" ENSG00000249751 "Endothelial cell surface expressed chemotaxis and apoptosis regulator" Q19T08 5 139448560-139462743 "Predicted membrane proteins" "Angiogenesis, Apoptosis, Chemotaxis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 12 "Adipocytes: 235.8;Endothelial cells: 214.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 122 "EFO-21: 172.1;HUVEC TERT2: 443.7;TIME: 330.9" HPA063337 Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA063337: AB_2732701" "unprognostic (5.91e-2)" "unprognostic (2.37e-2)" "unprognostic (1.95e-2)" "unprognostic (2.83e-2)" "unprognostic (3.69e-2)" "unprognostic (2.15e-3)" "unprognostic (3.95e-2)" "unprognostic (1.12e-1)" "unprognostic (2.29e-2)" "unprognostic (1.78e-1)" "unprognostic (2.78e-2)" "unprognostic (1.91e-1)" "unprognostic (1.83e-3)" "unprognostic (2.41e-3)" "unprognostic (1.36e-1)" "unprognostic (9.90e-2)" "unprognostic (2.91e-1)" 62.7 12.7 5.5 11.2 5.5 0.2 59.8 5.7 8.5 26.8 5.3 19.4 4.6 29.4 7.4 15.9 33.5 12.1 54.6 5.2 5.9 29.9 6.0 60.1 11.6 6.0 5.9 10.4 6.7 4.7 7.1 33.5 6.3 19.6 8.0 0.8 16.1 7.3 15.1 16.6 20.7 24.4 6.1 23.5 15.2 3.3 6.7 3.5 40.9 17.2 7.2 35.5 26.1 5.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.3 0.0 0.0 172.1 0.3 0.1 0.0 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 443.7 0.1 0.0 0.0 1.4 0.0 0.0 0.9 2.5 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.4 330.9 0.4 0.4 0.0 1.7 0.0 0.0 0.2 0.0 1.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 5.5 5.7 8.5 5.2 5.9 6.0 5.9 6.3 6.1 6.7 5.9 235.8 0.0 3.9 0.0 1.0 14.9 0.4 0.0 0.0 0.0 1.9 2.5 0.0 0.0 0.6 0.0 0.0 0.2 1.0 0.0 0.0 0.6 0.0 0.4 0.5 214.9 0.0 0.0 0.1 1.2 0.1 3.1 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 18.3 0.0 0.0 1.7 10.6 5.6 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.5 0.0 0.0 0.7 0.4 0.0 0.0 1.9 0.0 0.0 0.0 13.9 0.3 1.3 0.9 0.0 1.6 EHHADH ECHD ENSG00000113790 "Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase" Q08426 3 185190624-185281990 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Multifunctional enzyme, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 11 "kidney: 144.3;liver: 344.5" "Group enriched" "Detected in many" 10 "Hepatocytes: 289.0;Proximal tubular cells: 147.1" "Group enriched" "Detected in all" 7 "liver cancer: 42.2;renal cancer: 25.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036401, HPA042021" Enhanced NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036401: AB_10670165, HPA042021: AB_2677801" "unprognostic (1.20e-1)" "unprognostic (5.99e-2)" "unprognostic (2.17e-3)" "unprognostic (2.69e-2)" "unprognostic (6.82e-2)" "unprognostic (1.48e-1)" "unprognostic (4.79e-3)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (3.89e-2)" "unprognostic (3.19e-3)" "unprognostic (1.87e-1)" "prognostic favorable (1.28e-5)" "unprognostic (1.93e-1)" "unprognostic (1.53e-1)" "unprognostic (2.96e-2)" "unprognostic (2.80e-1)" 10.8 4.3 2.1 3.0 2.9 1.2 4.1 3.9 2.7 3.5 9.2 14.2 21.5 2.8 3.5 5.5 3.6 4.4 10.7 2.1 3.1 144.3 344.5 4.3 2.1 3.2 4.1 2.6 9.9 7.8 1.5 3.2 3.0 6.3 10.8 1.6 5.7 2.2 1.7 4.5 12.9 3.7 2.5 3.7 10.4 2.7 3.1 2.1 6.5 5.6 2.8 3.6 2.1 2.8 12.3 5.0 1.4 0.0 7.3 6.1 1.5 5.7 1.8 3.7 4.1 21.9 7.5 0.0 22.1 5.7 1.4 5.8 0.0 4.8 7.6 16.2 5.2 8.6 1.3 22.5 4.7 1.0 0.2 8.7 6.0 3.7 3.4 5.0 5.5 0.0 5.7 6.1 7.2 6.4 0.2 5.1 3.0 4.3 6.3 0.0 9.9 0.5 15.4 6.8 4.4 6.4 11.2 6.4 10.5 12.1 23.7 10.1 2.6 2.4 3.6 1.9 0.5 1.7 5.6 0.5 0.8 3.9 4.0 0.1 0.9 0.0 0.6 0.8 0.4 0.5 0.4 0.9 2.4 0.0 0.6 1.0 0.0 1.2 0.8 1.0 0.6 0.4 2.1 2.9 3.9 2.7 2.1 3.1 3.2 4.1 3.0 2.5 3.1 2.8 4.9 16.0 10.9 20.9 4.5 1.5 1.4 1.9 1.2 0.7 3.2 2.3 19.2 17.2 3.9 20.2 4.2 8.9 0.4 17.8 19.6 2.1 0.2 6.5 5.1 3.9 7.7 9.7 4.9 6.8 2.9 1.6 8.6 3.1 0.0 6.1 13.6 289.0 4.4 0.0 5.7 12.8 0.0 10.5 1.0 0.7 0.6 2.7 3.6 4.7 9.4 1.9 0.0 3.5 8.0 3.7 9.3 0.4 0.8 2.5 15.0 147.1 4.0 1.2 0.0 1.1 2.4 3.7 4.2 4.9 0.4 1.4 2.2 3.6 10.8 1.8 ENPEP "CD249, gp160" ENSG00000138792 "Glutamyl aminopeptidase" Q07075 4 110365733-110565285 "CD markers, Enzymes, Plasma proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 163.6;kidney: 90.0" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 663.2;Proximal tubular cells: 177.6;Sertoli cells: 157.8" "Cancer enriched" "Detected in many" 8 "renal cancer: 41.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.7;HEK 293: 7.5;MOLT-4: 1.8;SuSa: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005128 Enhanced NA NA 55000000 "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 45: Enterocytes - Digestion" "HPA005128: AB_1844795" "unprognostic (2.73e-3)" "unprognostic (2.84e-3)" "unprognostic (5.16e-3)" "unprognostic (3.48e-1)" "unprognostic (2.90e-1)" "unprognostic (8.74e-2)" "unprognostic (3.34e-2)" "unprognostic (1.03e-1)" "unprognostic (1.35e-2)" "unprognostic (1.22e-1)" "unprognostic (1.93e-1)" "unprognostic (9.47e-2)" "unprognostic (4.49e-3)" "unprognostic (3.43e-3)" "unprognostic (1.52e-2)" "unprognostic (8.46e-2)" "unprognostic (2.49e-3)" 11.6 2.2 0.4 1.5 0.5 0.1 4.8 0.4 2.5 1.6 1.8 1.2 36.6 12.9 4.1 1.7 2.3 4.4 4.3 0.6 0.5 90.0 29.0 4.6 0.8 0.9 0.8 1.2 1.3 45.2 1.2 15.5 0.7 1.8 0.8 0.0 1.1 1.2 2.3 0.7 163.6 10.6 0.5 9.2 1.2 0.5 0.4 4.4 5.0 8.9 0.3 2.6 1.6 0.8 0.0 0.2 0.0 0.0 0.1 0.1 2.7 0.4 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 1.8 0.3 0.3 0.1 0.0 0.1 0.0 0.3 0.0 0.3 0.1 0.1 0.0 1.3 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.4 2.5 0.6 0.5 0.9 0.8 0.7 0.5 0.4 0.8 10.7 0.0 2.0 1.6 1.1 1.7 0.1 0.0 0.0 0.0 0.2 0.1 3.9 0.0 0.3 11.0 0.0 37.0 0.0 1.5 17.6 0.0 0.5 3.1 40.7 2.2 1.8 0.0 7.3 0.0 3.5 15.4 0.0 2.3 0.0 0.0 1.4 31.4 2.7 0.0 2.9 28.4 2.0 1.0 1.9 0.2 0.6 1.1 0.0 1.0 0.0 0.0 1.0 0.0 0.8 0.0 31.6 0.4 0.1 0.2 663.2 177.6 1.7 0.0 157.8 0.8 54.1 0.0 0.2 0.1 1.0 58.6 1.9 0.5 42.1 0.1 ENPP3 "B10, CD203c, gp130RB13-6, PD-IBETA, PDNP3" ENSG00000154269 "Ectonucleotide pyrophosphatase/phosphodiesterase 3" O14638 6 131628442-131747418 "CD markers, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 32.1;intestine: 44.5" "Group enriched" "Detected in many" 5 "Endometrial ciliated cells: 160.0;Glandular and luminal cells: 387.2" "Cancer enriched" "Detected in many" 8 "renal cancer: 49.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 86 "basophil: 30.6" "Lineage enriched" "Detected in single" 86 "granulocytes: 30.6" "Group enriched" "Detected in some" 18 "HEL: 4.4;Hep G2: 14.6;HMC-1: 6.2" "Low region specificity" "Detected in some" "Region enriched" "Detected in single" 4 "spinal cord: 2.6" HPA043772 Enhanced "Secreted - unknown location" NA NA 1100000 "Cluster 38: Basophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 44: Endometrium - Transcription" "HPA043772: AB_10795616" "unprognostic (2.74e-1)" "unprognostic (1.99e-2)" "unprognostic (1.84e-1)" "unprognostic (5.41e-3)" "unprognostic (6.07e-2)" "unprognostic (4.86e-5)" "unprognostic (1.13e-1)" "unprognostic (7.20e-3)" "unprognostic (1.17e-1)" "unprognostic (1.13e-1)" "unprognostic (2.21e-3)" "unprognostic (2.34e-1)" "prognostic unfavorable (1.96e-4)" "unprognostic (2.80e-2)" "unprognostic (7.85e-2)" "unprognostic (2.29e-1)" "unprognostic (1.31e-3)" 1.2 6.2 0.4 1.1 0.4 0.1 6.6 0.9 0.5 32.1 0.2 9.3 16.2 3.8 1.2 0.5 2.3 1.3 0.1 0.3 0.5 10.0 5.0 0.9 0.5 0.5 0.6 0.5 0.1 0.3 0.1 0.1 0.5 2.4 8.4 0.3 18.1 15.6 0.1 0.6 44.5 0.8 0.4 0.3 0.5 0.8 0.5 9.6 0.3 0.2 0.4 0.4 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 4.4 0.0 14.6 0.0 0.1 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 30.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.4 0.9 0.5 0.3 0.5 0.5 0.6 0.5 0.4 0.5 0.4 0.4 0.0 1.1 5.2 0.2 0.0 2.6 0.7 1.2 0.2 1.0 0.6 0.3 0.0 2.5 0.0 0.0 0.0 0.2 9.2 1.9 0.0 1.6 160.0 46.3 1.4 0.0 2.1 2.1 0.0 0.1 0.5 0.0 387.2 36.0 0.1 0.7 1.7 0.1 0.0 4.1 1.5 0.0 0.6 1.1 0.4 1.2 1.5 1.8 2.8 0.0 0.1 1.0 3.5 0.9 0.0 1.9 0.7 0.3 2.7 53.3 9.1 5.4 0.1 0.0 0.2 1.0 2.5 0.8 0.0 0.6 0.1 2.2 0.1 4.9 1.1 ENPP6 MGC33971 ENSG00000164303 "Ectonucleotide pyrophosphatase/phosphodiesterase 6" Q6UWR7 4 184088706-184221230 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.4;kidney: 30.6;ovary: 12.5" "Cell type enhanced" "Detected in some" "Oligodendrocytes: 119.9;Peritubular cells: 35.3;Proximal tubular cells: 31.3;Theca cells: 23.9" "Cancer enriched" "Detected in some" 5 "glioma: 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 3.2;SH-SY5Y: 3.6;U-266/70: 2.9;U-266/84: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042740, HPA069197" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" NA NA 290000 "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "HPA042740: AB_10793984, HPA069197: " "unprognostic (4.81e-4)" "unprognostic (1.47e-1)" "unprognostic (3.54e-2)" "unprognostic (1.24e-1)" "unprognostic (2.56e-1)" "unprognostic (6.69e-3)" "unprognostic (3.07e-2)" "unprognostic (1.27e-2)" "unprognostic (1.03e-1)" "unprognostic (1.09e-1)" "unprognostic (7.60e-3)" "unprognostic (3.04e-2)" "unprognostic (1.72e-1)" "unprognostic (2.98e-2)" "unprognostic (2.82e-1)" "unprognostic (3.93e-3)" "unprognostic (2.01e-1)" 0.2 0.3 2.7 0.8 11.8 0.9 0.8 14.2 5.5 0.2 2.3 1.0 1.7 0.2 6.1 1.0 0.3 0.5 0.2 2.7 6.1 30.6 0.1 0.3 0.9 20.4 9.6 12.5 0.0 0.0 4.2 0.1 18.1 2.2 1.0 0.1 0.7 6.1 0.2 0.1 2.2 0.1 12.5 1.0 1.2 2.4 11.1 1.9 0.1 1.3 2.8 0.6 0.3 29.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 3.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.9 1.7 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 2.7 11.8 14.2 5.5 2.7 6.1 20.4 9.6 18.1 12.5 11.1 29.4 0.5 0.0 0.0 5.9 0.1 0.0 0.2 0.9 0.6 0.0 0.1 0.5 0.9 0.0 0.4 1.8 0.0 0.0 0.0 0.0 3.9 1.1 1.0 0.0 0.0 0.5 0.0 0.0 4.3 0.2 0.0 8.7 0.0 0.0 5.7 0.0 0.0 0.4 0.2 0.0 1.5 0.0 0.0 0.6 0.0 0.4 4.1 0.6 1.8 4.7 1.1 0.0 0.0 6.6 119.9 0.0 0.0 35.3 0.5 0.1 0.0 31.3 0.2 0.0 0.0 5.1 0.6 0.1 1.6 0.0 0.0 0.0 0.3 23.9 0.0 0.3 ENPP7 "alk-SMase, NPP7" ENSG00000182156 "Ectonucleotide pyrophosphatase/phosphodiesterase 7" Q6UWV6 17 79730943-79742219 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 104.6" "Group enriched" "Detected in some" 7 "Hepatocytes: 9.1;Proximal enterocytes: 22.7;Proximal tubular cells: 9.7" "Cancer enriched" "Detected in some" 6 "liver cancer: 6.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Hep G2: 1.2;Karpas-707: 2.1;U-266/70: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA024603 Approved "Intracellular and membrane" NA NA 450000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" "HPA024603: AB_1848174" "unprognostic (4.00e-2)" "unprognostic (1.16e-2)" "unprognostic (6.49e-2)" "unprognostic (4.83e-2)" "unprognostic (1.55e-1)" "unprognostic (2.65e-2)" "unprognostic (1.24e-1)" "unprognostic (1.01e-1)" "unprognostic (8.45e-4)" "unprognostic (4.83e-2)" "unprognostic (1.18e-2)" "unprognostic (1.52e-2)" "unprognostic (5.21e-2)" "unprognostic (1.25e-1)" "unprognostic (1.80e-2)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 11.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 104.6 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 9.1 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.7 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 ENTPD5 "CD39L4, NTPDase-5, PCPH" ENSG00000187097 "Ectonucleoside triphosphate diphosphohydrolase 5 (inactive)" O75356 14 73958010-74019399 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 107.2;kidney: 95.2;liver: 263.7" "Cell type enhanced" "Detected in all" "Distal enterocytes: 209.3;Hepatocytes: 134.8;Intestinal goblet cells: 77.1;Proximal enterocytes: 87.0" "Group enriched" "Detected in all" 5 "liver cancer: 18.2;prostate cancer: 39.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 18.3;eosinophil: 9.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 18.3" "Cell line enhanced" "Detected in all" "RT4: 57.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002927 Enhanced "Secreted to blood" NA NA 5900000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA002927: AB_1078744" "unprognostic (4.19e-1)" "unprognostic (9.63e-3)" "unprognostic (3.11e-2)" "unprognostic (2.06e-2)" "unprognostic (1.98e-1)" "unprognostic (3.87e-2)" "unprognostic (1.46e-1)" "unprognostic (1.19e-1)" "unprognostic (3.34e-1)" "unprognostic (6.01e-2)" "unprognostic (6.20e-2)" "unprognostic (2.55e-1)" "prognostic favorable (3.95e-5)" "unprognostic (1.25e-1)" "unprognostic (5.06e-2)" "unprognostic (1.76e-1)" "unprognostic (6.92e-3)" 8.2 7.7 5.0 11.4 7.3 8.0 12.4 7.1 6.7 7.3 7.1 94.6 72.1 6.3 7.7 11.3 5.7 12.1 7.7 5.1 6.3 95.2 263.7 6.5 5.5 7.6 7.3 6.7 4.9 7.7 5.0 5.6 7.8 37.7 107.2 9.4 10.7 4.4 15.0 8.1 68.4 9.7 6.5 6.0 42.3 8.6 7.3 4.6 6.1 9.1 5.6 16.9 7.2 9.0 9.5 7.8 8.2 15.1 16.5 15.5 9.4 9.6 7.9 6.4 7.1 5.6 10.9 10.6 4.7 12.8 6.0 10.8 8.5 14.1 7.2 8.8 4.0 7.9 5.7 30.9 15.5 4.7 8.8 12.9 14.0 8.7 18.2 8.8 13.1 17.1 8.8 15.4 9.7 13.6 5.4 5.6 2.5 8.5 15.7 6.0 8.0 5.2 11.4 57.1 5.8 6.0 16.6 12.9 9.2 6.4 18.7 4.1 10.8 12.6 12.7 7.5 7.2 10.1 16.9 8.3 8.0 8.8 11.5 18.3 1.2 9.4 2.5 2.3 1.3 1.4 1.3 1.8 1.7 1.5 2.1 2.1 0.1 0.5 1.4 0.9 1.6 1.3 5.0 7.3 7.1 6.7 5.1 6.3 7.6 7.3 7.8 6.5 7.3 9.0 8.0 16.0 6.7 8.1 4.9 3.7 6.2 8.9 5.2 6.6 15.0 7.9 5.2 10.0 11.3 7.3 4.2 8.2 4.3 209.3 25.4 6.9 19.5 10.0 13.6 7.0 16.2 36.6 5.9 12.9 6.7 7.9 23.0 25.8 1.3 9.6 9.7 134.8 6.2 10.1 8.2 77.1 14.2 9.7 1.9 12.7 2.8 5.2 5.4 11.2 5.4 4.9 8.2 2.0 11.3 9.1 58.4 5.7 3.6 28.5 87.0 63.1 6.4 12.2 13.1 6.0 5.9 27.2 19.1 8.5 3.4 3.3 4.9 10.3 60.9 39.0 EPHX2 ABHD20 ENSG00000120915 "Epoxide hydrolase 2" P34913 8 27490781-27545564 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aromatic hydrocarbons catabolism, Detoxification, Lipid metabolism" "Hydrolase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 333.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 180.0;Hepatocytes: 131.5;Proximal enterocytes: 399.0;Proximal tubular cells: 259.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory CD4 T-cell: 35.0;naive CD4 T-cell: 106.7;naive CD8 T-cell: 50.4;T-reg: 29.6" "Lineage enriched" "Detected in many" 23 "T-cells: 106.7" "Cell line enhanced" "Detected in many" "JURKAT: 139.4;K-562: 51.6;OE19: 102.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023094, HPA023660" Enhanced Enhanced Cytosol NA NA 1100000 "Cluster 32: T-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA023094: AB_1848214, HPA023660: AB_1848215" "unprognostic (1.30e-1)" "prognostic favorable (2.45e-4)" "unprognostic (2.99e-2)" "unprognostic (3.62e-2)" "unprognostic (1.76e-2)" "unprognostic (3.30e-3)" "unprognostic (1.26e-3)" "unprognostic (3.31e-3)" "unprognostic (1.46e-1)" "unprognostic (3.55e-2)" "unprognostic (4.14e-3)" "unprognostic (1.98e-1)" "prognostic favorable (1.98e-10)" "unprognostic (9.82e-2)" "unprognostic (1.73e-1)" "unprognostic (8.12e-2)" "unprognostic (2.26e-1)" 19.3 74.0 14.5 9.1 15.0 1.9 30.1 14.4 14.1 21.0 42.2 61.4 112.8 17.7 27.2 38.6 41.6 9.4 29.1 13.2 15.3 166.3 333.2 11.2 17.2 16.1 17.3 38.0 64.5 54.8 35.8 8.5 15.9 64.6 57.6 21.5 36.5 27.2 16.2 43.4 128.4 15.4 15.8 10.8 23.4 9.0 15.8 65.9 22.6 13.8 20.8 19.7 23.4 15.7 15.3 10.1 6.3 8.1 0.4 0.0 4.8 1.3 0.9 0.7 0.2 8.0 10.1 0.1 5.9 4.1 3.2 10.7 1.1 2.6 0.5 0.0 4.7 22.5 1.1 24.8 3.4 0.1 4.5 8.6 10.7 0.1 1.1 2.5 0.5 139.4 51.6 0.2 0.0 4.7 14.9 0.5 10.1 102.4 17.2 0.1 0.1 0.4 8.7 2.2 5.1 16.0 12.1 14.2 15.0 4.6 21.8 4.2 0.2 0.0 3.8 1.8 0.1 12.5 10.1 0.2 0.4 0.1 0.1 0.1 0.1 0.0 7.8 0.0 11.3 4.5 35.0 12.7 0.1 2.5 106.7 50.4 0.2 4.6 0.1 0.2 29.6 20.0 14.5 15.0 14.4 14.1 13.2 15.3 16.1 17.3 15.9 15.8 15.8 15.7 6.3 6.4 17.0 16.3 6.1 11.9 18.6 10.1 29.6 34.1 17.2 18.4 23.7 20.0 9.7 27.6 79.2 22.8 1.0 82.7 180.0 8.8 7.5 6.9 4.8 9.4 23.4 3.8 3.0 6.4 2.5 12.1 15.8 1.5 5.7 17.4 17.5 131.5 2.2 33.7 7.2 63.4 2.0 4.6 1.2 4.8 29.8 3.6 5.4 2.8 2.6 91.5 3.1 7.5 5.1 3.1 83.7 18.8 4.5 20.5 399.0 259.3 24.1 52.4 0.0 11.5 10.2 1.3 13.9 39.2 18.3 8.2 11.9 78.5 101.3 10.8 ERG "erg-3, p55" ENSG00000157554 "ETS transcription factor ERG" P11308 21 38380027-38661780 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 94.4;Endothelial cells: 105.5;Hepatic stellate cells: 69.9;Microglial cells: 88.1" "Cancer enriched" "Detected in all" 4 "prostate cancer: 18.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 138.3;MOLT-4: 47.7;REH: 151.5;TIME: 113.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018377, HPA046598" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "CAB018377: AB_675518, HPA046598: AB_2679715" "unprognostic (2.14e-1)" "prognostic unfavorable (6.18e-6)" "unprognostic (6.44e-3)" "unprognostic (8.64e-3)" "unprognostic (5.65e-2)" "unprognostic (1.91e-1)" "unprognostic (9.03e-4)" "unprognostic (4.30e-2)" "unprognostic (2.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (4.31e-3)" "unprognostic (3.88e-2)" "unprognostic (2.64e-2)" "unprognostic (5.63e-3)" 24.6 4.1 5.1 7.1 5.5 7.6 20.0 5.0 5.5 10.0 3.0 5.4 3.4 11.6 1.9 5.2 9.1 12.0 12.4 4.5 5.1 12.8 6.1 19.6 7.5 5.9 5.4 4.4 4.9 2.4 2.4 24.3 6.2 7.1 3.4 0.5 3.7 4.3 7.9 4.9 6.5 12.0 4.7 26.6 4.6 1.5 7.0 4.1 10.0 9.9 3.7 9.2 6.9 5.4 0.0 0.0 1.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.2 22.3 0.0 0.1 0.9 0.0 0.0 138.3 0.1 0.0 0.0 0.0 1.0 47.7 0.0 0.5 0.0 0.0 151.5 0.0 0.0 0.0 0.1 0.1 0.0 1.1 0.2 0.0 0.0 0.0 0.0 113.4 0.7 2.2 0.5 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.1 5.5 5.0 5.5 4.5 5.1 5.9 5.4 6.2 4.7 7.0 5.4 94.4 0.0 3.9 0.3 0.7 3.4 1.7 0.6 3.4 0.0 0.6 4.3 3.8 4.3 1.3 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.7 0.7 0.4 105.5 0.0 13.5 13.3 0.0 0.0 5.7 0.0 2.1 24.0 4.4 69.9 1.3 0.3 0.0 1.7 0.4 0.0 5.9 3.4 2.1 0.9 0.9 3.6 88.1 0.2 0.0 0.0 7.1 1.4 0.0 0.0 0.0 1.5 1.4 0.0 0.0 0.0 0.1 0.0 2.4 3.7 0.3 1.4 0.5 3.4 0.0 0.6 0.5 0.3 0.6 ERICH4 "C19orf69, LOC100170765" ENSG00000204978 "Glutamate rich 4" A6NGS2 19 41443156-41444765 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "intestine: 42.5;kidney: 16.6" "Group enriched" "Detected in some" 10 "Proximal enterocytes: 189.7;Proximal tubular cells: 90.2" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "CACO-2: 2.6;Hep G2: 6.2;THP-1: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA042632, HPA048484" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Cytosol "HPA042632: AB_2678090, HPA048484: AB_2680415" "unprognostic (1.41e-1)" "unprognostic (3.05e-1)" "unprognostic (9.52e-2)" "unprognostic (1.24e-1)" "unprognostic (2.76e-1)" "unprognostic (4.03e-5)" "unprognostic (8.53e-2)" "unprognostic (7.54e-2)" "unprognostic (1.97e-1)" "unprognostic (3.09e-2)" "unprognostic (1.04e-1)" "unprognostic (2.79e-1)" "unprognostic (2.35e-1)" "unprognostic (1.16e-1)" 0.6 0.0 0.3 0.1 0.1 0.0 0.6 0.1 0.1 0.4 0.1 0.3 42.5 0.6 0.0 0.2 0.5 0.3 2.0 0.0 0.0 16.6 0.0 1.1 0.3 0.3 0.1 0.2 0.1 0.0 0.0 0.2 0.2 0.2 0.0 0.1 0.3 0.0 1.7 0.2 39.2 0.0 0.1 0.6 0.2 0.8 0.2 0.0 0.3 0.0 0.0 0.3 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.3 0.1 0.2 0.1 0.2 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.1 13.7 0.2 3.7 0.7 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 4.7 0.0 0.0 0.0 1.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.1 189.7 90.2 0.0 0.0 0.0 0.7 0.2 0.8 0.6 0.0 0.0 0.0 0.3 0.1 3.0 0.0 ESPL1 "ESP1, KIAA0165, SEPA" ENSG00000135476 "Extra spindle pole bodies like 1, separase" Q14674 12 53268299-53293638 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Chromosome partition" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.5;esophagus: 15.4;lymphoid tissue: 10.7" "Cell type enhanced" "Detected in many" "Ionocytes: 22.4;Proximal enterocytes: 22.6;Squamous epithelial cells: 7.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "CAB012185, HPA073188" Approved Supported Nucleoplasm,Vesicles NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 45: Enterocytes - Digestion" Nucleoplasm Vesicles "CAB012185: AB_304056, HPA073188: " "unprognostic (1.57e-1)" "unprognostic (3.56e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (5.32e-5)" "unprognostic (2.91e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (2.01e-5)" "prognostic unfavorable (7.14e-4)" "unprognostic (1.59e-2)" "unprognostic (2.48e-1)" "unprognostic (4.17e-3)" "unprognostic (1.18e-2)" "unprognostic (7.42e-13)" "prognostic favorable (7.10e-4)" "unprognostic (2.39e-1)" "unprognostic (7.41e-2)" "unprognostic (1.42e-1)" 0.4 0.2 0.0 2.4 0.0 8.5 0.5 0.0 0.0 3.5 0.0 1.5 3.9 0.2 0.0 15.4 0.2 0.4 0.1 0.0 0.0 0.9 0.6 0.4 4.4 0.0 0.0 0.1 0.1 0.0 0.0 1.1 0.0 0.1 1.4 0.0 2.0 0.1 0.0 2.6 4.3 0.7 0.0 1.0 0.9 6.2 0.1 10.7 0.1 0.0 4.9 0.6 5.9 0.0 27.8 23.6 27.6 21.1 0.6 1.9 17.5 15.9 8.6 28.8 19.2 15.8 22.7 49.9 9.5 6.8 17.4 20.2 32.6 9.9 14.3 13.7 32.8 30.6 24.1 11.1 0.1 19.5 25.2 0.6 0.6 15.5 7.6 2.8 15.4 22.2 42.6 41.0 9.1 29.2 30.6 16.4 22.5 14.5 12.9 29.3 30.2 21.4 4.2 11.6 18.9 15.8 11.9 20.4 10.1 13.0 36.9 12.7 8.2 14.5 27.2 11.9 25.5 32.5 29.7 31.9 8.2 19.0 27.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.3 0.6 0.9 0.3 0.5 0.6 0.0 1.0 1.3 0.9 0.0 0.4 3.7 0.0 1.9 0.6 2.7 0.0 0.2 0.8 0.2 0.8 1.0 3.5 1.3 0.7 0.0 2.3 1.1 3.6 0.7 0.0 4.4 0.7 6.8 2.6 0.0 0.4 2.7 22.4 0.6 2.1 1.2 0.0 1.3 0.0 1.0 0.0 0.0 0.0 0.0 0.5 1.5 1.3 0.4 2.1 0.4 22.6 6.6 0.2 0.0 0.0 0.4 0.9 5.5 4.1 7.4 0.6 0.3 0.4 0.1 2.8 0.4 ESPN DFNB36 ENSG00000187017 Espin B1AK53 1 6424776-6461367 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing Actin-binding "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 129.1;retina: 117.8;testis: 145.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 175.5;Early spermatids: 137.5;Late spermatids: 461.6;Muller glia cells: 272.5;Paneth cells: 186.3;Proximal enterocytes: 512.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebellum: 13.4;thalamus: 6.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 48.9;Hep G2: 81.5;SK-BR-3: 160.1;T-47d: 53.6" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "cerebellum: 2.6" "HPA028674, HPA060220" Enhanced Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA028674: AB_10601316, HPA060220: AB_2684224" "unprognostic (5.06e-2)" "unprognostic (1.18e-2)" "unprognostic (2.69e-1)" "unprognostic (1.28e-1)" "unprognostic (2.19e-2)" "unprognostic (1.41e-1)" "unprognostic (1.59e-1)" "unprognostic (2.28e-1)" "unprognostic (1.16e-1)" "unprognostic (5.71e-2)" "unprognostic (7.48e-3)" "unprognostic (5.53e-2)" "unprognostic (6.26e-3)" "unprognostic (5.51e-2)" "unprognostic (1.16e-1)" "unprognostic (3.04e-2)" "unprognostic (1.17e-2)" 0.6 5.7 0.4 2.6 1.0 28.0 9.2 13.4 1.0 30.3 0.2 28.2 90.4 2.4 39.9 34.3 18.6 0.3 0.9 0.4 1.7 63.4 129.1 3.2 0.3 0.6 1.3 0.4 0.9 26.8 42.1 0.9 1.1 10.0 6.8 117.8 9.4 6.2 0.8 91.7 89.5 0.8 0.3 0.9 2.7 145.3 6.1 1.6 0.4 0.0 1.7 1.3 22.3 0.5 14.1 0.7 0.6 0.1 0.0 0.0 48.9 0.0 0.0 0.2 0.0 29.9 1.5 0.5 6.5 0.0 0.1 32.6 2.3 0.1 0.0 2.0 0.7 0.4 0.7 81.5 0.0 0.6 2.7 0.1 0.6 0.0 0.0 0.0 0.0 1.0 17.6 0.0 0.0 28.2 0.2 1.0 0.6 3.8 12.2 0.0 0.4 10.9 0.2 0.1 21.0 0.7 3.7 160.1 5.0 0.3 53.6 7.4 15.6 0.1 0.8 0.6 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 1.0 13.4 1.0 0.4 1.7 0.6 1.3 1.1 0.3 6.1 0.5 0.2 0.0 0.6 0.0 0.8 7.8 2.4 4.5 12.5 5.6 10.7 3.9 1.4 11.5 3.8 9.2 68.8 3.0 0.2 175.5 13.7 0.2 137.5 19.1 0.9 0.8 6.0 8.2 0.2 3.1 0.5 0.3 5.6 12.4 0.0 0.0 3.9 109.4 0.2 0.0 0.2 36.3 8.2 3.2 0.9 461.6 3.7 1.5 0.0 0.0 0.0 272.5 0.0 0.0 0.1 0.1 186.3 2.2 0.0 1.6 512.1 102.2 9.0 72.5 0.0 0.0 0.2 12.3 3.9 17.6 22.7 6.6 1.5 0.0 35.3 2.9 ESRRB "DFNB35, ERR2, ERRb, ERRbeta, ESRL2, NR3B2" ENSG00000119715 "Estrogen related receptor beta" O95718 14 76310712-76501837 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "retina: 36.5" "Cell type enhanced" "Detected in some" "Distal tubular cells: 13.7;Early spermatids: 14.1;Horizontal cells: 55.5;Late spermatids: 37.6;Rod photoreceptor cells: 40.3" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 1.3;K-562: 5.0;U-266/70: 2.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA074772 Supported Nucleoplasm,Cytosol NA NA "Cluster 77: Retina - Visual perception" "Cluster 1: K-562 - Erythropoiesis" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm Cytosol "HPA074772: " "unprognostic (1.12e-1)" "unprognostic (1.34e-2)" "unprognostic (6.28e-2)" "unprognostic (3.92e-5)" "unprognostic (5.18e-2)" "unprognostic (3.15e-2)" "unprognostic (2.14e-1)" "unprognostic (1.48e-1)" "unprognostic (2.28e-2)" "unprognostic (2.24e-2)" "unprognostic (2.16e-2)" "unprognostic (4.11e-2)" "unprognostic (2.68e-1)" "unprognostic (3.46e-1)" "unprognostic (1.89e-1)" "unprognostic (2.12e-4)" "unprognostic (4.40e-2)" 0.0 0.0 0.4 0.0 0.4 0.0 0.3 0.4 0.4 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 4.9 0.3 0.6 6.6 0.0 0.0 0.0 1.5 1.2 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 36.5 0.0 0.0 6.5 0.0 0.0 0.0 0.6 0.1 2.4 1.2 0.9 0.1 0.0 1.6 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.2 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.0 0.2 0.0 0.6 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.4 0.0 0.2 2.3 0.7 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.4 0.3 0.6 1.5 1.2 0.7 0.6 0.9 0.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 2.4 1.0 0.4 5.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 13.7 0.0 14.1 0.0 0.0 0.8 0.0 0.0 1.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.5 2.0 0.0 0.0 0.0 0.0 37.6 0.0 0.1 0.0 3.7 0.0 4.6 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 40.3 0.0 0.1 0.8 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ETNK2 "EKI2, FLJ10761" ENSG00000143845 "Ethanolamine kinase 2" Q9NVF9 1 204131062-204152044 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "kidney: 108.1;liver: 235.5;testis: 125.0" "Group enriched" "Detected in many" 4 "Early spermatids: 417.0;Late spermatids: 1337.3" "Cancer enhanced" "Detected in all" "liver cancer: 32.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTCEpi: 53.8;MCF7: 55.1" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 8 "basal ganglia: 22.6" HPA057167 Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" "HPA057167: AB_2683358" "unprognostic (1.64e-1)" "unprognostic (4.17e-2)" "unprognostic (2.56e-2)" "unprognostic (7.81e-2)" "prognostic unfavorable (4.11e-4)" "unprognostic (1.95e-1)" "unprognostic (1.99e-2)" "unprognostic (1.13e-1)" "unprognostic (9.39e-3)" "unprognostic (4.28e-2)" "unprognostic (6.54e-2)" "unprognostic (4.35e-2)" "prognostic favorable (6.50e-4)" "unprognostic (5.50e-3)" "unprognostic (4.69e-2)" "unprognostic (2.00e-2)" "unprognostic (1.20e-1)" 14.4 6.1 12.8 2.1 12.5 2.8 17.4 7.9 12.0 18.8 28.3 5.7 1.9 10.8 29.9 23.9 13.1 5.3 6.3 10.6 14.0 108.1 235.5 3.3 2.1 10.5 13.4 36.1 9.5 18.5 25.6 4.3 11.1 13.7 2.1 5.7 27.7 16.2 2.0 20.3 3.7 6.5 8.5 7.2 4.9 125.0 15.1 3.7 10.6 4.1 9.3 10.0 26.0 7.5 11.3 3.8 11.0 20.9 4.0 1.3 10.9 11.4 25.2 15.6 6.8 19.2 5.4 0.4 18.4 2.8 18.2 9.9 19.7 15.9 10.7 0.4 17.3 0.2 2.5 30.6 16.2 0.5 0.7 5.4 53.8 3.2 0.7 8.0 11.1 11.9 1.6 0.4 2.0 55.1 3.2 0.3 23.0 0.4 8.4 0.8 13.0 0.4 13.4 4.3 2.9 15.4 7.2 33.6 5.4 35.1 32.5 0.7 0.7 4.4 23.8 1.0 8.4 0.5 0.2 0.5 0.3 0.6 6.3 0.0 0.1 0.0 2.2 0.0 2.1 0.0 0.5 1.3 0.0 0.1 1.3 1.6 0.1 0.8 0.0 0.0 0.3 0.6 12.8 12.5 7.9 12.0 10.6 14.0 10.5 13.4 11.1 8.5 15.1 7.5 1.3 0.0 0.0 1.3 1.0 4.1 13.8 8.2 1.8 4.2 12.3 11.6 1.1 4.3 2.5 3.7 4.2 6.1 1.6 0.1 39.2 9.5 417.0 4.5 1.9 2.1 1.2 13.5 1.2 6.3 9.2 6.4 1.1 3.2 8.9 47.4 6.8 196.9 0.8 0.0 2.9 0.1 2.0 6.5 1.1 1337.3 29.2 1.6 10.6 0.0 0.0 3.8 1.0 2.5 0.2 4.5 0.0 42.2 0.0 14.9 0.3 147.2 3.1 0.8 0.0 4.1 4.4 11.0 7.4 16.1 2.4 9.4 2.9 34.1 0.2 13.5 FABP1 L-FABP ENSG00000163586 "Fatty acid binding protein 1" P07148 2 88122982-88128062 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "intestine: 5501.2;liver: 13065.3" "Cell type enhanced" "Detected in some" "Distal enterocytes: 12424.2;Hepatocytes: 7459.2;Paneth cells: 3975.2;Proximal enterocytes: 15929.5" "Group enriched" "Detected in many" 14 "colorectal cancer: 175.1;liver cancer: 437.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "CACO-2: 122.1;Hep G2: 393.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002305, HPA028275" Enhanced Approved Nucleoplasm,Cytosol NA NA 45000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Cytosol" "CAB002305: AB_563728, HPA028275: AB_10600909" "unprognostic (1.91e-1)" "unprognostic (7.91e-3)" "unprognostic (5.47e-2)" "unprognostic (1.96e-1)" "unprognostic (2.03e-2)" "unprognostic (2.35e-1)" "unprognostic (7.99e-2)" "unprognostic (8.92e-2)" "unprognostic (2.29e-1)" 6.7 0.8 0.6 160.2 0.6 0.0 10.7 0.5 1.8 0.7 0.4 5501.2 4751.8 13.0 0.0 2.6 3.9 0.5 0.8 0.6 0.7 727.6 13065.3 0.9 3.7 0.6 0.5 0.9 1.0 0.3 0.8 0.7 0.5 2.6 3416.4 0.1 0.5 8.4 0.9 0.5 4727.6 230.4 0.5 2.8 15.8 1.1 0.6 0.1 0.5 0.4 0.1 0.6 0.8 0.7 0.0 0.0 0.0 0.0 0.0 0.0 33.3 0.0 0.0 0.0 0.0 122.1 0.0 1.4 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.2 0.0 393.9 0.0 7.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 33.0 0.5 0.0 0.0 0.3 6.4 37.4 0.0 0.5 3.6 24.7 2.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.1 11.8 0.7 0.4 0.1 2.5 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.5 1.8 0.6 0.7 0.6 0.5 0.5 0.5 0.6 0.7 0.0 0.0 0.0 0.3 42.6 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.3 120.1 0.0 60.7 0.0 0.2 0.0 12424.2 156.5 0.0 0.0 0.0 0.0 7.5 261.9 149.7 0.1 0.0 1.2 0.1 2.6 0.0 129.2 0.0 105.3 7459.2 1.5 0.0 0.1 1061.1 0.0 166.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 3975.2 0.0 0.0 0.1 15929.5 2014.4 0.0 0.0 0.0 0.0 0.1 0.1 1.5 0.0 0.0 1.4 29.3 0.0 1708.4 0.0 FADS6 ENSG00000172782 "Fatty acid desaturase 6" 17 74877302-74893781 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 10.7;epididymis: 18.2;intestine: 14.8" "Cell type enriched" "Detected in some" 13 "Proximal enterocytes: 72.2" "Cancer enhanced" "Detected in some" "liver cancer: 2.6" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in some" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016802 Uncertain NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 45: Enterocytes - Digestion" "HPA016802: AB_2669448" "unprognostic (2.41e-2)" "unprognostic (6.80e-3)" "unprognostic (2.64e-1)" "unprognostic (4.68e-3)" "unprognostic (4.73e-2)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (1.07e-1)" "unprognostic (6.41e-2)" "unprognostic (6.98e-4)" "unprognostic (3.38e-2)" "unprognostic (7.53e-2)" "unprognostic (1.14e-2)" "unprognostic (6.71e-2)" "unprognostic (2.27e-1)" "unprognostic (8.45e-2)" "unprognostic (1.79e-1)" 0.2 7.1 4.5 0.5 3.5 1.5 0.5 6.6 9.1 0.6 0.0 0.8 7.5 0.2 18.2 3.2 0.1 0.0 0.2 2.0 2.0 1.1 6.1 0.2 0.6 10.2 2.4 0.3 0.4 0.5 0.1 0.2 10.7 0.1 0.7 1.2 0.3 0.3 0.4 7.7 14.8 0.2 0.9 4.1 0.2 0.7 5.1 0.4 0.4 0.2 0.8 1.2 1.1 3.6 0.2 0.3 0.5 0.4 0.0 1.0 0.7 0.5 0.0 0.1 0.2 0.8 0.3 0.3 0.1 0.5 0.3 0.3 0.7 0.0 0.2 0.1 0.0 0.5 1.6 0.6 0.3 0.4 0.4 0.3 0.0 1.1 0.4 0.2 0.0 0.4 0.4 1.4 0.6 0.6 0.3 1.1 0.3 0.2 0.5 0.2 0.1 0.5 0.3 0.3 0.4 0.4 0.5 0.2 0.1 0.5 0.2 0.5 0.3 0.3 0.7 0.6 0.5 0.5 0.2 0.3 1.0 0.3 0.5 1.1 0.6 0.4 0.2 0.6 0.2 0.3 0.3 0.3 0.1 0.5 0.3 0.4 2.0 0.8 1.5 0.5 0.2 0.0 4.5 3.5 6.6 9.1 2.0 2.0 10.2 2.4 10.7 0.9 5.1 3.6 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.0 1.8 1.5 0.1 0.0 1.1 0.0 0.0 0.0 0.0 2.1 0.0 3.7 0.0 0.0 0.8 0.0 0.1 0.3 0.0 0.0 5.2 0.2 0.1 0.3 0.0 0.2 0.0 1.1 0.4 4.0 0.3 1.7 5.4 1.1 0.0 0.0 0.4 0.2 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.2 0.0 5.1 0.0 0.0 1.1 72.2 1.9 0.0 0.5 0.0 1.1 0.4 0.0 2.0 1.7 0.6 3.8 0.2 0.4 0.7 1.3 FAH ENSG00000103876 "Fumarylacetoacetate hydrolase" P16930 15 80152490-80186946 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 301.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 266.8;Proximal tubular cells: 305.5" "Cancer enhanced" "Detected in all" "liver cancer: 23.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 34.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 316.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041370, HPA044093" Enhanced Approved Nucleoplasm,Cytosol NA NA 220000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA041370: AB_2677438, HPA044093: AB_2678806" "unprognostic (3.15e-1)" "unprognostic (5.65e-2)" "unprognostic (1.64e-1)" "unprognostic (6.16e-2)" "unprognostic (2.33e-3)" "prognostic unfavorable (8.51e-4)" "unprognostic (1.19e-2)" "unprognostic (5.83e-2)" "unprognostic (2.51e-2)" "unprognostic (5.21e-2)" "unprognostic (1.80e-1)" "unprognostic (1.23e-1)" "unprognostic (2.17e-2)" "unprognostic (4.21e-2)" "unprognostic (2.99e-1)" "unprognostic (2.93e-1)" "unprognostic (8.98e-2)" 99.2 65.4 16.0 7.0 17.1 20.0 59.0 16.6 21.1 19.2 15.1 13.8 14.6 19.3 50.4 15.2 23.0 9.7 20.3 16.3 18.8 65.0 301.5 20.0 5.7 17.9 19.6 26.4 9.9 18.4 16.8 7.8 16.9 16.6 11.9 1.6 14.8 13.6 31.0 10.9 16.8 13.5 17.2 19.1 14.2 20.8 17.4 6.7 14.5 27.7 5.8 16.4 15.8 17.5 20.1 34.4 13.5 17.0 60.2 62.2 32.9 24.3 56.8 26.2 22.3 22.0 35.9 0.4 39.0 52.6 36.8 29.1 46.8 59.6 25.1 12.5 28.5 166.6 18.0 112.1 316.6 79.6 88.8 107.5 37.1 22.9 39.7 84.2 37.4 38.3 71.1 35.7 50.3 31.0 22.3 42.0 9.9 15.5 37.6 12.2 19.3 123.4 77.0 25.2 0.7 8.3 27.4 76.7 77.9 21.6 58.3 55.0 126.1 46.8 30.0 25.5 42.7 32.7 69.5 13.8 99.6 187.5 26.9 34.5 18.8 3.3 9.6 8.1 2.3 0.1 2.4 6.0 25.3 0.1 3.1 2.7 1.3 5.7 8.4 1.9 2.5 9.7 16.0 17.1 16.6 21.1 16.3 18.8 17.9 19.6 16.9 17.2 17.4 17.5 3.0 3.2 13.8 9.8 4.1 6.8 17.5 30.8 15.4 0.4 19.1 13.7 15.5 21.5 12.5 33.1 0.0 37.9 4.9 9.3 52.8 9.3 7.5 3.0 16.2 3.2 4.2 24.4 0.4 3.5 14.1 16.6 3.6 4.0 41.9 6.3 8.9 266.8 72.5 0.0 2.5 13.0 24.4 21.4 6.6 13.5 9.9 30.5 19.6 1.0 5.7 7.3 3.1 2.5 0.6 4.5 12.8 7.9 5.2 9.7 54.1 305.5 5.3 0.4 0.0 9.2 11.2 1.5 2.1 18.2 5.7 22.0 7.7 8.7 22.4 16.4 FAHD1 "C16orf36, DKFZP566J2046" ENSG00000180185 "Fumarylacetoacetate hydrolase domain containing 1" Q6P587 16 1826941-1840207 "Enzymes, Predicted intracellular proteins" "Hydrolase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 64.1" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 112.2;Proximal tubular cells: 210.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025530, HPA043226, HPA043534" Enhanced Enhanced Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria Nucleoplasm "CAB025530: , HPA043226: AB_2678370, HPA043534: AB_2678535" "unprognostic (3.71e-1)" "unprognostic (1.25e-2)" "prognostic favorable (8.27e-4)" "unprognostic (1.99e-1)" "unprognostic (6.74e-2)" "unprognostic (1.01e-3)" "unprognostic (2.89e-2)" "unprognostic (4.32e-1)" "unprognostic (1.13e-1)" "unprognostic (5.36e-2)" "unprognostic (1.65e-1)" "unprognostic (1.38e-1)" "prognostic favorable (2.80e-14)" "unprognostic (1.02e-1)" "unprognostic (1.66e-1)" "unprognostic (1.26e-1)" "unprognostic (3.31e-2)" 12.3 21.4 9.1 8.5 9.4 10.0 9.4 9.3 11.1 8.3 9.2 22.6 36.1 9.7 8.0 19.3 6.9 12.1 19.9 10.9 11.1 64.1 58.5 7.1 7.4 10.7 10.0 8.0 15.8 12.1 9.5 7.5 10.1 9.4 14.2 6.7 11.2 10.7 30.7 17.1 27.1 8.7 8.8 8.4 21.0 10.1 9.4 7.9 7.8 24.7 6.4 11.3 11.1 9.9 20.1 44.6 20.9 36.9 27.0 19.5 12.9 32.4 16.0 21.1 22.9 28.6 20.4 12.8 26.6 20.2 32.7 40.5 16.4 25.8 19.0 19.3 39.0 11.5 38.7 67.0 26.2 20.0 21.2 25.8 33.3 19.3 12.9 17.8 27.8 15.3 12.1 12.8 26.8 92.5 10.9 30.1 12.4 18.4 33.0 24.6 28.3 36.4 76.8 24.9 40.4 33.6 42.3 33.5 52.0 13.8 49.4 13.4 41.1 34.4 24.6 20.5 17.8 18.6 42.3 15.1 22.0 14.5 15.1 15.8 40.8 16.5 25.1 51.5 22.5 37.2 24.7 27.3 42.6 32.7 27.0 24.8 3.5 38.1 38.4 33.1 28.4 24.3 9.1 9.4 9.3 11.1 10.9 11.1 10.7 10.0 10.1 8.8 9.4 9.9 14.6 25.6 16.4 2.9 11.2 14.0 13.3 29.6 13.1 19.8 12.4 15.7 42.9 27.1 17.2 42.3 27.1 22.6 10.9 50.8 50.9 57.2 89.8 16.8 19.8 16.3 29.3 36.4 8.0 39.2 14.2 15.5 17.3 18.2 5.1 13.8 9.7 35.5 30.5 18.5 8.6 25.6 24.4 9.1 14.2 45.0 14.6 13.7 16.0 4.7 18.9 17.4 20.6 3.0 6.4 34.9 36.7 15.4 4.0 11.2 112.2 210.9 14.4 24.2 13.1 12.7 16.5 9.9 9.1 27.2 24.0 15.3 9.8 30.3 52.7 9.6 FAM151A "C1orf179, MGC27169" ENSG00000162391 "Family with sequence similarity 151 member A" Q8WW52 1 54609181-54623556 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 66.3;kidney: 174.5" "Group enriched" "Detected in some" 15 "Proximal enterocytes: 478.5;Proximal tubular cells: 294.8" "Group enriched" "Detected in many" 5 "liver cancer: 2.3;renal cancer: 3.2;testis cancer: 5.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 44 "CACO-2: 78.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA016840 Approved NA NA 10000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA016840: AB_2669461" "unprognostic (1.89e-1)" "unprognostic (6.90e-3)" "unprognostic (3.73e-2)" "unprognostic (1.97e-6)" "unprognostic (1.71e-2)" "unprognostic (4.84e-3)" "unprognostic (1.02e-1)" "unprognostic (3.46e-2)" "unprognostic (2.87e-1)" "unprognostic (1.05e-2)" "unprognostic (4.91e-3)" "unprognostic (9.99e-2)" "prognostic favorable (4.09e-5)" "unprognostic (5.85e-2)" "unprognostic (8.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.40e-3)" 0.6 0.3 0.5 0.6 1.5 0.2 0.1 1.6 0.9 0.0 5.9 2.4 2.4 0.1 0.0 0.3 0.0 0.1 3.0 0.6 0.5 174.5 16.7 0.0 5.3 2.7 2.8 0.3 0.6 0.0 0.1 0.0 1.5 0.1 1.3 0.3 0.5 0.0 1.0 0.1 66.3 0.0 0.4 0.8 0.7 0.6 2.2 0.2 0.4 0.0 1.8 0.1 0.0 0.6 0.7 0.1 0.1 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 78.9 0.9 0.0 0.3 0.0 0.2 1.1 0.0 0.0 0.0 0.5 0.0 1.7 0.4 0.4 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 1.5 0.0 0.0 0.8 0.0 0.0 1.6 0.4 0.5 0.1 0.0 0.0 0.3 0.0 0.5 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.5 1.6 0.9 0.6 0.5 2.7 2.8 1.5 0.4 2.2 0.6 0.0 0.0 0.0 3.6 2.4 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 7.3 0.0 0.0 0.0 9.3 13.7 0.0 5.2 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.2 0.0 0.0 0.4 16.8 0.0 0.3 0.0 14.3 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 25.0 0.0 0.0 0.0 478.5 294.8 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.0 0.1 18.1 0.0 FAM205C FAM205CP ENSG00000187791 "Family with sequence similarity 205 member C" A6NFA0 9 34889066-34895764 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 38 "testis: 28.9" "Group enriched" "Detected in some" 91 "Early spermatids: 275.6;Late spermatids: 489.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 103 "THP-1: 14.8" "Not detected" "Not detected" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 34: Spermatids - Unknown function" "unprognostic (1.29e-1)" "unprognostic (1.90e-1)" "unprognostic (3.64e-2)" "unprognostic (8.64e-2)" "unprognostic (2.63e-1)" "unprognostic (1.84e-1)" "unprognostic (7.73e-2)" "unprognostic (1.85e-4)" "unprognostic (1.48e-3)" 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.7 0.1 0.1 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.1 0.1 28.9 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 4.2 0.0 0.0 0.0 1.9 0.0 275.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 489.3 1.2 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.6 0.0 0.5 0.0 0.0 0.0 2.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FBLN5 "ARMD3, DANCE, EVEC, UP50" ENSG00000140092 "Fibulin 5" Q9UBX5 14 91869411-91947987 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Age-related macular degeneration, Charcot-Marie-Tooth disease, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Fibroblasts: 209.4;Leydig cells: 626.6;Peritubular cells: 794.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.6" "Group enriched" "Detected in many" 19 "granulocytes: 6.6;T-cells: 1.8" "Cell line enhanced" "Detected in many" "ASC diff: 457.1;ASC TERT1: 234.6;BJ: 202.0;BJ hTERT+: 202.5;fHDF/TERT166: 394.6;HSkMC: 216.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000848, HPA000868, CAB025843" Supported Uncertain "Plasma membrane" "Secreted to extracellular matrix" NA NA 12000000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB025843: , HPA000848: AB_1078620, HPA000868: AB_1078619" "unprognostic (5.53e-3)" "unprognostic (1.14e-1)" "unprognostic (7.78e-2)" "unprognostic (9.29e-2)" "unprognostic (5.55e-3)" "unprognostic (4.73e-2)" "prognostic favorable (6.75e-4)" "unprognostic (5.21e-3)" "unprognostic (4.76e-2)" "unprognostic (1.25e-2)" "unprognostic (3.74e-2)" "unprognostic (1.90e-1)" "unprognostic (7.26e-2)" "unprognostic (1.56e-3)" "unprognostic (1.73e-1)" "unprognostic (5.18e-2)" "unprognostic (3.17e-3)" 182.2 73.4 10.7 17.7 12.8 7.5 110.4 7.4 12.5 124.9 15.7 80.3 19.1 178.4 40.0 26.8 143.0 130.2 211.1 9.4 8.6 108.4 29.3 164.8 25.5 15.5 10.9 107.3 46.4 16.8 14.5 67.0 14.2 49.0 20.6 0.6 55.8 70.9 30.4 66.9 52.7 88.7 13.1 130.9 68.9 35.6 12.7 21.8 79.5 36.0 15.7 117.5 93.3 7.5 0.0 1.6 0.2 0.0 457.1 234.6 22.5 202.0 202.5 5.8 4.5 4.7 0.0 0.0 4.2 394.6 0.6 0.1 9.8 1.0 1.0 0.0 2.3 0.4 4.7 0.0 74.2 0.0 0.1 216.6 0.4 3.9 14.1 2.8 10.4 0.1 0.0 0.1 25.3 0.4 0.5 0.5 0.5 0.0 0.5 0.4 30.2 0.2 1.2 0.1 0.2 0.1 12.3 0.7 2.6 7.0 2.9 0.3 1.9 3.2 6.6 3.8 0.1 0.1 0.0 0.2 0.4 0.0 0.0 6.6 0.1 2.2 0.8 0.2 0.5 0.0 0.3 0.1 0.0 0.1 1.1 1.8 2.5 0.0 0.2 0.0 0.1 0.4 10.7 12.8 7.4 12.5 9.4 8.6 15.5 10.9 14.2 13.1 12.7 7.5 31.4 83.3 13.1 0.0 2.1 9.2 2.4 7.1 1.8 0.0 11.2 9.3 5.2 0.0 11.5 5.5 0.0 2.5 2.5 0.1 5.9 4.7 5.9 13.3 67.4 15.2 0.0 0.4 2.6 4.7 2.5 209.4 2.0 12.0 2.5 1.8 34.2 0.4 7.8 0.0 3.6 0.1 18.3 2.5 18.4 27.5 626.6 5.8 21.4 15.9 1.6 0.0 8.2 5.0 2.3 2.2 0.0 794.8 0.7 1.3 0.0 32.5 21.4 0.0 6.6 28.0 14.5 3.0 2.8 1.3 8.7 3.7 15.5 3.5 0.4 1.2 FBN3 KIAA1776 ENSG00000142449 "Fibrillin 3" Q75N90 19 8065402-8149592 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 2.4;salivary gland: 4.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Cardiomyocytes: 2.4;Inhibitory neurons: 3.4;Oligodendrocyte precursor cells: 17.1" "Cancer enhanced" "Detected in many" "testis cancer: 8.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.8;CACO-2: 3.7;NTERA-2: 12.3;REH: 18.6;SuSa: 4.5" "Not detected" "Not detected" HPA049482 Uncertain "Secreted to extracellular matrix" NA NA 2400000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA049482: AB_2680786" "unprognostic (9.66e-3)" "unprognostic (5.15e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (5.15e-4)" "unprognostic (4.14e-2)" "unprognostic (5.14e-3)" "unprognostic (6.26e-2)" "unprognostic (4.10e-3)" "unprognostic (3.17e-2)" "unprognostic (8.94e-2)" "unprognostic (4.61e-2)" "unprognostic (1.53e-1)" "unprognostic (2.76e-2)" "unprognostic (1.34e-2)" "unprognostic (2.57e-1)" "unprognostic (1.17e-2)" "unprognostic (3.17e-1)" 0.1 0.0 0.2 0.0 0.3 0.0 0.2 0.3 0.5 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.5 0.0 0.1 0.3 0.6 2.4 0.1 1.4 0.0 0.5 0.6 0.1 0.0 0.0 0.7 0.0 0.6 0.9 0.1 0.0 4.0 0.0 0.3 0.2 0.1 0.1 0.5 0.0 0.1 0.5 0.6 0.5 1.9 0.9 0.0 0.0 0.0 0.6 0.0 0.0 0.9 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 3.7 0.4 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 12.3 0.0 0.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.5 0.3 0.6 0.5 0.6 0.6 0.5 0.6 0.6 0.0 6.4 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.2 0.0 0.8 0.0 0.0 0.2 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 17.1 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 FBP1 FBP ENSG00000165140 "Fructose-bisphosphatase 1" P09467 9 94603133-94640249 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Gluconeogenesis" "Allosteric enzyme, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 324.4;kidney: 297.8;liver: 893.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 500.4;Macrophages: 238.6;Proximal enterocytes: 1095.0;Proximal tubular cells: 864.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 404.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HaCaT: 75.2;MCF7: 243.4;OE19: 54.5;RT4: 157.0;U-698: 170.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA005857, HPA012513, CAB033869" Enhanced Approved Mitochondria NA NA 21000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB033869: AB_1121520, HPA005857: AB_1848445, HPA012513: AB_1848446" "unprognostic (4.95e-2)" "unprognostic (1.40e-2)" "unprognostic (1.40e-1)" "prognostic favorable (5.16e-4)" "unprognostic (1.13e-2)" "unprognostic (1.37e-1)" "prognostic favorable (1.79e-4)" "unprognostic (6.94e-3)" "unprognostic (4.52e-2)" "unprognostic (7.79e-2)" "unprognostic (7.59e-2)" "unprognostic (1.12e-1)" "prognostic favorable (6.86e-7)" "unprognostic (6.91e-2)" "unprognostic (3.22e-2)" "unprognostic (1.07e-1)" "prognostic favorable (1.64e-5)" 13.7 27.4 1.6 12.7 1.8 15.0 41.4 1.8 5.7 19.9 2.6 29.8 324.4 3.6 15.8 2.7 7.1 34.4 2.9 1.5 2.2 297.8 893.2 165.9 6.8 3.6 2.6 1.1 41.4 107.9 8.6 3.0 2.9 25.8 30.5 0.7 53.2 28.9 1.3 8.1 258.1 8.8 2.6 12.2 85.6 2.5 3.2 2.2 16.8 0.9 7.8 70.8 6.7 3.8 0.5 0.1 0.3 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.1 0.6 3.8 0.0 0.3 0.8 0.1 75.2 0.1 0.0 0.1 0.0 0.3 0.6 2.9 1.3 0.0 1.5 18.8 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.2 0.3 0.2 243.4 0.1 4.4 1.1 54.5 9.5 0.0 0.9 1.9 0.0 157.0 0.7 5.6 0.6 44.5 0.0 0.9 26.7 7.7 0.2 0.1 1.0 0.8 0.0 0.3 1.1 170.4 0.0 1.4 0.1 63.3 68.4 404.3 7.9 162.3 11.7 3.0 4.6 4.6 90.1 3.2 16.2 8.3 12.1 15.4 90.7 32.1 2.3 33.1 1.6 1.8 1.8 5.7 1.5 2.2 3.6 2.6 2.9 2.6 3.2 3.8 2.8 76.9 182.8 0.0 10.3 0.8 8.9 0.7 0.0 0.1 62.4 24.3 0.7 102.9 41.0 62.5 0.0 11.1 14.8 26.1 111.6 21.5 0.1 4.0 0.4 4.8 31.9 24.4 0.9 62.7 1.7 5.4 102.4 5.2 47.4 16.0 12.1 500.4 177.6 0.0 0.8 61.4 0.0 79.9 32.1 1.5 1.5 238.6 12.4 1.9 20.1 2.6 8.2 0.5 0.3 24.0 77.6 4.1 18.3 11.9 1095.0 864.1 9.1 0.2 6.6 0.6 2.0 0.6 1.3 0.8 1.0 10.1 12.1 0.5 90.4 68.1 FCAMR "CD351, FCA/MR, FKSG87" ENSG00000162897 "Fc fragment of IgA and IgM receptor" Q8WWV6 1 206957965-206970625 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "kidney: 38.1;lymphoid tissue: 26.2" "Cell type enriched" "Detected in some" 8 "Proximal tubular cells: 32.9" "Group enriched" "Detected in some" 5 "liver cancer: 2.4;renal cancer: 5.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA056505 Enhanced NA NA 5300000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA056505: AB_2732604" "unprognostic (2.94e-1)" "unprognostic (1.06e-1)" "unprognostic (8.53e-2)" "unprognostic (2.92e-1)" "unprognostic (7.44e-2)" "unprognostic (4.55e-3)" "unprognostic (2.69e-3)" "unprognostic (1.08e-4)" "unprognostic (3.61e-2)" "unprognostic (1.25e-1)" "unprognostic (1.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (1.29e-1)" "unprognostic (3.88e-2)" "unprognostic (2.08e-1)" "unprognostic (1.26e-1)" 0.2 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 1.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 38.1 7.9 0.0 23.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.0 1.0 0.0 0.0 2.3 0.6 0.0 0.0 1.0 0.0 0.0 26.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.9 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 32.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.1 FCER1G ENSG00000158869 "Fc fragment of IgE receptor Ig" P30273 1 161215234-161220699 "FDA approved drug targets, Predicted membrane proteins" "Immunity, Innate immunity" "IgE-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 441.6;lymphoid tissue: 470.1" "Group enriched" "Detected in many" 9 "dendritic cells: 726.6;granulocytes: 705.6;Hofbauer cells: 2318.6;Kupffer cells: 1950.8;Langerhans cells: 1526.3;Macrophages: 1971.3;monocytes: 808.9;NK-cells: 1037.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 11 "basophil: 1987.3;classical monocyte: 3240.2;intermediate monocyte: 5333.6;myeloid DC: 2386.3;neutrophil: 1831.0;NK-cell: 1750.9;non-classical monocyte: 6984.5;plasmacytoid DC: 3315.6" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "HEL: 77.8;HMC-1: 301.7;THP-1: 276.1;U-266/84: 90.1;U-937: 87.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022108, HPA026872" Supported NA NA 270000 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB022108: , HPA026872: AB_1848473" "unprognostic (3.71e-2)" "unprognostic (2.52e-2)" "unprognostic (2.40e-2)" "unprognostic (8.73e-3)" "unprognostic (1.46e-1)" "unprognostic (4.28e-2)" "unprognostic (3.10e-3)" "unprognostic (1.84e-1)" "unprognostic (3.25e-1)" "unprognostic (9.63e-2)" "unprognostic (2.28e-2)" "unprognostic (5.67e-2)" "prognostic unfavorable (1.83e-6)" "unprognostic (1.99e-1)" "unprognostic (6.28e-2)" "unprognostic (2.04e-2)" "unprognostic (7.87e-2)" 251.7 86.5 34.0 275.6 33.8 441.6 62.9 35.5 66.0 52.5 47.5 82.7 44.9 30.7 38.7 30.6 72.0 101.5 53.1 33.7 42.0 40.3 177.3 286.6 160.9 53.4 48.7 19.9 22.3 26.8 26.9 211.0 50.1 31.0 113.2 8.3 42.9 38.8 11.9 21.0 60.6 160.3 41.5 470.1 39.4 14.5 49.9 62.7 25.5 34.6 82.5 254.6 21.7 65.4 0.2 0.0 0.7 1.3 1.8 0.7 0.4 0.5 0.2 0.5 0.8 2.2 0.1 0.5 0.7 0.0 0.3 0.2 0.5 0.0 0.4 0.3 1.5 77.8 0.6 14.0 0.3 16.1 301.7 6.0 3.3 2.3 0.2 0.7 0.4 1.8 0.1 7.3 2.4 0.5 1.4 37.9 1.6 0.0 0.0 0.1 6.7 0.2 0.5 0.4 0.3 1.0 0.6 0.1 2.7 1.4 0.2 276.1 0.4 1.8 0.4 0.9 1.1 3.0 90.1 0.9 1.7 87.1 0.5 1987.3 3240.2 307.3 13.6 5333.6 15.9 28.2 10.6 10.6 2386.3 9.0 17.3 45.0 1831.0 1750.9 6984.5 3315.6 21.8 4265.5 34.0 33.8 35.5 66.0 33.7 42.0 53.4 48.7 50.1 41.5 49.9 65.4 12.8 86.6 147.7 0.7 35.9 39.6 1.5 0.2 1.8 0.1 5.2 22.1 6.8 15.7 27.3 18.4 0.0 14.5 726.6 1.0 0.0 1.9 3.0 1.0 0.9 38.6 1.8 79.3 0.1 1.0 18.8 18.3 1.1 1.0 705.6 0.5 41.0 13.6 2318.6 0.0 0.2 0.5 0.0 1950.8 1526.3 9.4 5.3 1971.3 80.0 12.2 808.9 0.2 1037.1 0.0 0.1 1.0 1.4 1.2 10.1 1.3 0.4 5.4 15.3 2.3 72.3 3.8 11.2 1.0 2.5 1.4 35.9 23.7 133.3 0.4 0.6 1.8 FGF1 "AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-alpha, FGFA, GLIO703, HBGF1" ENSG00000113578 "Fibroblast growth factor 1" P05230 5 142592178-142698070 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 295.2;choroid plexus: 125.8" "Cell type enhanced" "Detected in many" "Astrocytes: 75.1;Cardiomyocytes: 62.4;Muller glia cells: 69.4;Oligodendrocytes: 119.8" "Cancer enriched" "Detected in many" 12 "glioma: 33.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 44.6;BJ hTERT+: 33.0;BJ hTERT+ SV40 Large T+: 35.9;BJ hTERT+ SV40 Large T+ RasG12V: 45.0;HBF TERT88: 64.3;hTEC/SVTERT24-B: 45.4;LHCN-M2: 30.6;U-2 OS: 33.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003265, CAB017519" Enhanced Supported Nucleoplasm "Secreted in other tissues" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "CAB017519: AB_629473, HPA003265: AB_1848522" "unprognostic (1.25e-2)" "unprognostic (2.43e-1)" "unprognostic (1.06e-1)" "unprognostic (3.41e-3)" "unprognostic (2.55e-2)" "unprognostic (3.52e-1)" "unprognostic (2.77e-1)" "unprognostic (2.39e-1)" "unprognostic (3.63e-1)" "unprognostic (1.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.54e-1)" "prognostic favorable (2.59e-5)" "unprognostic (3.72e-4)" "unprognostic (2.49e-1)" "prognostic favorable (3.45e-5)" "unprognostic (3.01e-4)" 17.9 3.3 206.3 1.6 259.3 1.1 12.5 213.9 295.2 1.3 125.8 2.4 1.0 3.1 7.9 2.0 1.7 2.5 50.2 183.5 245.5 66.5 1.7 2.8 1.2 236.2 237.7 0.9 0.8 4.3 6.5 2.1 259.9 1.8 1.3 18.8 7.3 2.3 2.2 1.7 1.2 2.5 225.4 6.9 0.8 2.0 244.3 1.5 5.6 7.8 2.0 1.2 1.0 272.8 5.6 0.3 0.3 1.5 1.1 3.3 1.8 44.6 33.0 35.9 45.0 0.2 0.2 1.3 3.1 15.4 2.1 0.7 0.0 3.5 64.3 0.2 0.0 0.0 0.8 0.4 0.6 0.0 0.4 1.6 1.1 45.4 2.7 9.7 0.0 0.2 0.0 1.6 30.6 0.7 0.1 0.9 1.4 0.1 1.4 0.2 1.5 0.6 1.5 0.2 1.1 2.3 0.1 0.9 0.6 8.0 0.0 0.2 1.1 5.8 33.0 0.8 21.3 0.8 0.4 0.3 8.2 0.3 1.6 0.0 0.0 0.4 0.4 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.1 0.3 0.3 0.0 0.1 0.2 0.1 0.0 206.3 259.3 213.9 295.2 183.5 245.5 236.2 237.7 259.9 225.4 244.3 272.8 1.4 0.0 0.0 75.1 0.1 0.4 5.0 5.7 7.4 3.5 1.2 25.4 62.4 0.0 2.1 20.2 16.7 1.1 0.1 0.0 0.0 1.1 0.4 0.0 0.7 4.8 0.0 0.0 13.0 0.0 0.5 4.7 0.0 0.2 0.0 0.0 1.1 0.0 0.1 0.0 14.6 0.0 12.2 0.0 0.0 1.4 0.0 0.2 3.6 29.0 0.0 69.4 0.0 15.1 119.8 0.6 0.0 0.4 0.0 5.3 0.0 0.3 0.1 11.6 6.6 0.5 23.4 0.1 0.1 0.6 0.0 0.8 0.4 0.0 0.0 0.7 FMN2 ENSG00000155816 "Formin 2" Q9NZ56 1 240014348-240475187 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, Protein transport, Stress response, Transport" "Actin-binding, Developmental protein" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.0;parathyroid gland: 19.7;retina: 16.7" "Cell type enhanced" "Detected in many" "Astrocytes: 758.1;Excitatory neurons: 537.5;Horizontal cells: 124.5;Inhibitory neurons: 366.7;Oligodendrocyte precursor cells: 154.3" "Group enriched" "Detected in some" 8 "glioma: 5.9;testis cancer: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 70.8;BJ hTERT+: 39.4;fHDF/TERT166: 73.8;LHCN-M2: 87.9;U-138 MG: 48.9;WM-115: 69.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050649 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Actin filaments" "HPA050649: AB_2681202" "unprognostic (1.55e-2)" "unprognostic (8.21e-2)" "unprognostic (4.01e-2)" "unprognostic (8.06e-2)" "unprognostic (2.77e-1)" "unprognostic (1.76e-1)" "unprognostic (7.97e-3)" "unprognostic (2.11e-2)" "unprognostic (2.93e-1)" "unprognostic (3.92e-2)" "unprognostic (3.35e-3)" "unprognostic (4.08e-1)" "unprognostic (1.11e-2)" "unprognostic (8.03e-3)" "unprognostic (9.78e-2)" "unprognostic (3.10e-2)" "unprognostic (1.40e-3)" 1.2 5.1 27.6 0.2 29.6 0.0 0.5 11.8 46.0 0.4 0.0 6.8 0.2 1.4 0.9 0.7 1.9 1.2 0.1 28.4 20.9 3.6 0.0 0.3 0.0 21.2 29.7 2.4 1.0 19.7 9.0 0.2 14.4 1.6 1.6 16.7 0.3 2.6 0.1 0.2 0.9 1.7 16.0 0.2 0.7 2.2 39.0 0.0 0.5 0.2 0.1 0.3 0.3 30.9 0.0 2.1 6.6 0.0 20.2 15.3 0.0 70.8 39.4 31.0 16.3 0.0 0.0 0.0 0.0 73.8 1.2 0.0 1.3 0.0 28.8 0.0 5.8 0.0 0.7 0.0 0.1 0.0 0.0 1.7 0.0 8.5 1.9 17.0 0.0 0.0 0.0 0.0 87.9 0.0 0.0 0.1 2.3 0.0 2.2 0.0 0.2 0.0 0.0 0.0 12.0 10.6 0.0 0.1 0.3 0.2 2.1 0.1 0.3 48.9 0.2 16.0 18.2 0.0 0.0 0.0 10.4 0.0 69.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.6 29.6 11.8 46.0 28.4 20.9 21.2 29.7 14.4 16.0 39.0 30.9 0.0 0.0 0.0 758.1 0.0 0.1 0.0 0.0 0.0 30.6 0.2 0.3 1.6 0.0 0.0 1.8 50.1 0.1 0.0 4.7 0.0 0.0 15.2 4.3 0.7 0.5 12.1 0.0 537.5 0.0 0.1 1.4 0.0 1.1 0.0 0.8 2.9 0.1 0.1 124.5 366.7 0.5 0.0 0.6 0.6 3.0 0.3 0.1 1.8 31.9 0.0 2.3 0.0 154.3 17.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.3 1.8 4.4 0.0 0.0 0.5 0.0 3.1 1.6 0.0 FMO1 ENSG00000010932 "Flavin containing dimethylaniline monoxygenase 1" Q01740 1 171248471-171285978 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "kidney: 199.0" "Group enriched" "Detected in many" 7 "Proximal enterocytes: 97.9;Proximal tubular cells: 196.9" "Cancer enriched" "Detected in many" 8 "renal cancer: 18.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HSkMC: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078132 Approved NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA078132: " "unprognostic (1.04e-1)" "unprognostic (1.05e-2)" "unprognostic (5.87e-2)" "unprognostic (1.34e-1)" "unprognostic (5.32e-3)" "unprognostic (1.89e-2)" "unprognostic (1.04e-1)" "unprognostic (4.04e-1)" "unprognostic (9.16e-2)" "unprognostic (9.03e-2)" "unprognostic (1.36e-2)" "unprognostic (2.23e-1)" "prognostic favorable (2.81e-4)" "unprognostic (6.49e-4)" "unprognostic (1.40e-1)" "unprognostic (3.58e-1)" "unprognostic (1.37e-1)" 5.1 5.6 0.1 0.5 0.1 0.0 10.0 0.1 0.3 6.3 0.3 0.4 0.1 3.1 0.1 3.5 4.2 5.2 0.7 0.1 0.1 199.0 2.9 1.5 0.4 0.1 0.1 5.0 2.4 1.1 1.8 2.3 0.1 0.4 0.2 0.0 5.4 0.7 0.1 10.4 20.2 4.2 0.1 0.0 0.9 1.6 0.1 7.4 2.3 0.8 10.8 2.5 1.7 0.1 0.0 0.0 0.0 0.0 2.7 1.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 20.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 5.0 0.0 0.0 0.3 3.0 3.2 0.5 0.0 12.5 0.0 0.5 1.1 10.0 2.8 0.0 3.7 0.0 0.3 0.0 0.0 13.7 0.0 0.7 0.0 0.1 1.1 0.0 0.0 0.1 0.0 0.1 18.7 0.0 0.0 0.0 3.2 0.0 0.3 0.4 0.0 0.1 2.9 0.0 0.0 0.0 1.5 10.8 0.9 1.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.8 2.6 0.0 0.1 97.9 196.9 0.0 0.0 6.6 0.5 4.7 0.0 0.1 1.4 2.3 0.8 1.0 2.6 1.4 0.1 FN3K ENSG00000167363 "Fructosamine 3 kinase" Q9H479 17 82735615-82751196 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 79.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 90.1;Proximal tubular cells: 167.2;Rod photoreceptor cells: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 34.3;Hep G2: 66.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059151, HPA061358" Supported Approved Mitochondria NA NA 180000 "Cluster 35: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA059151: AB_2683931, HPA061358: AB_2684490" "unprognostic (4.74e-2)" "unprognostic (9.19e-2)" "unprognostic (4.22e-2)" "prognostic favorable (1.10e-4)" "unprognostic (6.10e-2)" "unprognostic (1.39e-1)" "unprognostic (6.45e-2)" "unprognostic (9.86e-2)" "unprognostic (5.08e-2)" "unprognostic (2.61e-1)" "prognostic favorable (2.40e-4)" "unprognostic (6.66e-2)" "prognostic favorable (1.39e-6)" "unprognostic (2.68e-2)" "unprognostic (8.02e-2)" "unprognostic (4.77e-1)" "unprognostic (1.22e-2)" 14.4 47.3 47.4 2.9 64.3 12.0 8.4 64.4 56.6 10.4 36.8 15.5 22.4 9.4 7.0 4.6 12.5 6.9 47.5 46.5 54.3 49.6 48.1 7.8 2.4 63.3 56.8 22.3 18.1 21.9 22.4 5.3 62.7 12.5 9.5 13.8 28.5 12.1 23.5 5.3 14.5 6.6 49.4 4.6 17.4 5.2 55.6 1.0 10.2 10.9 2.3 8.8 7.9 79.8 1.3 16.1 4.4 23.2 6.9 5.7 2.9 2.9 2.2 5.4 2.7 21.0 3.3 0.2 3.9 2.6 4.5 0.6 34.3 2.5 2.0 1.0 2.4 12.5 12.9 66.2 18.8 0.3 10.1 4.9 9.0 2.1 0.0 5.7 10.6 1.0 22.4 0.6 1.1 1.8 0.2 0.2 2.9 7.6 13.0 2.1 0.3 0.1 11.5 4.5 7.0 22.7 5.3 1.2 15.8 3.8 15.4 4.5 2.5 0.4 1.6 5.6 4.3 1.2 0.3 0.1 0.4 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.4 64.3 64.4 56.6 46.5 54.3 63.3 56.8 62.7 49.4 55.6 79.8 3.9 3.2 2.0 8.8 1.9 1.5 3.7 1.5 14.8 41.9 4.5 3.7 5.8 4.3 2.5 31.3 47.9 11.7 2.6 5.7 90.1 3.2 0.2 11.6 3.0 5.2 5.4 49.2 10.2 1.2 2.6 8.6 47.9 25.9 1.3 6.9 4.2 5.4 8.2 32.0 13.0 10.4 6.1 1.0 3.4 0.4 5.3 5.7 12.4 5.6 1.2 36.2 1.0 6.0 17.1 1.7 7.3 3.0 9.1 3.9 28.2 167.2 2.5 72.9 0.0 6.1 9.8 0.8 4.1 12.8 1.8 8.3 3.1 18.6 9.5 3.5 FOLR2 FRβ ENSG00000165457 "Folate receptor beta" P14207 11 72216601-72221950 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Transport Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 168.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 1114.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 64.2;intermediate monocyte: 50.6" "Group enriched" "Detected in many" 4 "dendritic cells: 18.7;monocytes: 64.2" "Cell line enriched" "Detected in some" 5 "U-698: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 15000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (2.03e-1)" "unprognostic (6.58e-3)" "prognostic unfavorable (8.42e-4)" "unprognostic (1.47e-1)" "unprognostic (2.76e-1)" "unprognostic (2.83e-1)" "unprognostic (1.39e-1)" "unprognostic (3.36e-1)" "unprognostic (3.38e-1)" "unprognostic (2.51e-1)" "unprognostic (8.11e-2)" "unprognostic (1.16e-1)" "unprognostic (3.91e-3)" "unprognostic (6.16e-3)" "unprognostic (1.14e-1)" "prognostic favorable (8.41e-4)" "unprognostic (7.98e-3)" 119.1 55.0 10.7 28.2 11.0 10.8 31.7 8.2 18.6 27.9 13.8 36.0 19.5 13.5 12.4 31.6 16.8 80.1 38.6 10.9 9.5 10.8 44.8 39.7 78.5 9.3 10.7 16.0 7.1 7.9 6.1 168.4 11.4 6.1 46.7 0.2 12.8 16.7 5.9 9.8 29.6 46.3 9.3 27.7 21.0 13.0 16.2 28.7 9.1 26.3 29.0 81.3 6.3 16.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.7 0.2 0.2 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.2 0.0 0.2 0.0 18.6 0.5 0.8 0.0 0.0 64.2 0.0 0.3 50.6 0.0 9.5 0.0 0.0 18.7 4.0 0.0 0.0 1.1 1.8 13.7 0.2 0.0 20.4 10.7 11.0 8.2 18.6 10.9 9.5 9.3 10.7 11.4 9.3 16.2 16.1 3.4 0.0 0.6 0.0 8.0 7.9 0.1 0.0 1.2 0.0 0.1 1.1 2.2 1.5 0.0 0.0 0.0 7.6 0.6 0.0 0.0 0.0 0.9 0.3 0.1 2.3 0.0 0.0 0.0 0.0 6.0 2.4 0.0 0.5 2.5 0.0 2.2 1.7 1114.8 0.0 0.0 0.0 0.0 229.3 98.8 2.5 1.5 199.4 0.0 15.9 5.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 2.1 0.1 0.0 0.2 0.0 0.3 0.0 2.5 1.2 0.6 0.7 1.3 5.1 16.0 1.2 0.1 0.0 0.1 FTCD ENSG00000160282 "Formimidoyltransferase cyclodeaminase" O95954 21 46136262-46155579 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Histidine metabolism" "Lyase, Multifunctional enzyme, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 939.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 131.5;Early spermatids: 104.7;Hepatocytes: 444.9;Late spermatids: 124.3;Proximal tubular cells: 395.1" "Cancer enriched" "Detected in some" 8 "liver cancer: 87.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 30 "Hep G2: 92.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA020073, HPA030928, HPA030929, HPA036114" Enhanced Approved "Plasma membrane,Cytosol" No NA 1600000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "Plasma membrane" "HPA020073: AB_1849005, HPA030928: AB_2673664, HPA030929: AB_2673665, HPA036114: AB_2674947" "unprognostic (1.71e-1)" "unprognostic (2.27e-1)" "unprognostic (4.62e-5)" "unprognostic (2.90e-2)" "unprognostic (1.13e-1)" "unprognostic (2.96e-1)" "prognostic favorable (1.70e-4)" "unprognostic (1.85e-1)" "unprognostic (2.67e-1)" "unprognostic (1.99e-1)" "prognostic favorable (6.78e-5)" "unprognostic (1.80e-1)" "prognostic favorable (5.78e-4)" "unprognostic (3.80e-2)" "unprognostic (3.60e-1)" "unprognostic (9.37e-2)" "unprognostic (2.10e-1)" 0.4 1.7 5.4 0.2 6.8 0.0 0.4 3.6 8.4 1.3 3.0 1.3 1.3 1.2 0.4 0.3 0.9 0.1 1.6 4.9 4.7 155.7 939.8 0.2 0.2 4.6 3.9 3.0 4.0 0.0 3.4 0.0 5.6 4.2 0.0 0.0 0.2 0.6 0.4 0.3 1.7 0.0 3.5 0.5 0.5 13.9 4.4 0.0 0.9 0.0 0.0 1.3 1.0 5.5 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.0 3.1 0.0 0.3 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.6 0.6 0.0 92.9 0.0 0.6 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.7 0.0 0.0 1.9 0.0 0.1 0.2 0.2 0.0 0.2 0.0 0.9 0.3 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.3 0.4 0.5 0.0 0.3 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 5.4 6.8 3.6 8.4 4.9 4.7 4.6 3.9 5.6 3.5 4.4 5.5 0.0 0.0 0.0 1.0 8.1 0.1 0.0 0.0 0.0 1.3 0.2 0.5 1.5 131.5 0.0 9.2 0.0 0.0 0.1 0.0 46.9 0.0 104.7 0.1 0.4 1.8 0.0 61.5 10.5 0.0 0.0 0.6 0.0 0.2 0.0 0.6 30.4 444.9 0.1 3.3 5.9 0.1 0.0 28.9 0.0 124.3 3.1 1.6 0.0 1.0 0.0 0.2 0.0 1.0 18.5 0.0 0.1 2.6 0.0 0.5 0.3 395.1 0.0 0.4 0.0 0.2 0.5 39.2 17.9 0.2 0.4 0.0 3.6 0.1 0.2 0.1 FUOM "C10orf125, FLJ26016, FucM, FucU" ENSG00000148803 "Fucose mutarotase" A2VDF0 10 133355158-133358025 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 228.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 564.7;Hofbauer cells: 172.0;Proximal enterocytes: 690.7;Proximal tubular cells: 368.1" "Cancer enriched" "Detected in all" 5 "liver cancer: 61.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039207 Approved NA NA 2000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "HPA039207: AB_10795033" "unprognostic (1.15e-2)" "unprognostic (1.16e-1)" "unprognostic (4.48e-2)" "unprognostic (7.19e-2)" "unprognostic (4.82e-1)" "unprognostic (2.66e-2)" "unprognostic (1.66e-2)" "unprognostic (2.45e-1)" "unprognostic (6.25e-2)" "unprognostic (7.56e-2)" "unprognostic (4.50e-2)" "unprognostic (8.67e-2)" "unprognostic (3.65e-2)" "unprognostic (4.02e-2)" "unprognostic (1.50e-1)" "unprognostic (4.88e-3)" "unprognostic (1.65e-1)" 12.9 8.8 4.2 11.3 4.4 6.6 13.0 4.0 7.2 7.3 8.2 12.0 52.0 5.5 3.2 8.7 7.9 9.6 17.4 4.2 4.6 46.7 228.3 14.1 16.8 5.3 4.7 7.3 18.3 8.0 6.0 5.2 5.7 7.0 5.4 0.3 28.8 3.6 3.0 7.4 46.8 3.6 4.9 23.7 8.5 5.6 5.1 6.1 6.6 2.6 8.0 7.9 7.7 4.8 23.3 7.2 13.6 28.4 3.8 9.2 24.8 18.3 20.7 6.5 8.1 46.4 12.4 0.0 20.7 13.8 0.0 1.2 4.9 6.3 0.5 8.4 4.9 22.3 10.3 50.7 20.1 25.2 14.8 9.6 0.2 2.6 1.4 3.0 9.2 22.9 22.2 29.7 13.9 23.0 3.9 33.6 9.5 13.5 3.2 21.8 0.4 13.0 7.5 0.0 1.4 11.0 6.7 20.6 25.3 6.8 0.2 38.3 18.7 0.1 18.4 0.0 0.1 15.5 2.7 16.7 5.5 10.2 7.1 0.1 68.9 6.5 16.0 73.2 14.7 36.0 14.0 13.4 57.2 34.5 14.9 13.1 3.3 17.1 15.7 79.0 10.4 28.6 4.2 4.4 4.0 7.2 4.2 4.6 5.3 4.7 5.7 4.9 5.1 4.8 20.4 6.4 10.0 0.0 32.7 12.1 9.2 8.5 6.2 0.1 12.2 25.7 10.9 22.8 11.4 9.2 0.0 10.3 25.1 79.2 31.3 13.6 3.7 3.8 9.7 14.1 3.0 24.4 0.6 12.7 9.0 25.6 8.6 7.7 27.3 15.5 25.0 564.7 172.0 0.0 1.2 49.7 6.1 103.0 55.4 10.3 10.2 68.7 26.6 1.9 85.6 3.5 13.4 0.0 1.0 12.5 119.5 3.8 29.6 17.8 690.7 368.1 4.0 1.1 13.1 11.6 14.9 20.2 23.7 10.0 9.9 6.6 21.5 4.1 61.1 12.1 FUT3 "CD174, LE" ENSG00000171124 "Fucosyltransferase 3 (Lewis blood group)" P21217 19 5842888-5851474 "Blood group antigen proteins, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 158.7;intestine: 72.3;retina: 79.3;salivary gland: 84.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 154.7;Intestinal goblet cells: 78.7;Pancreatic endocrine cells: 49.0;Paneth cells: 88.9;Proximal enterocytes: 85.2;Undifferentiated cells: 65.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 41.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 46.3;hTCEpi: 6.9;OE19: 20.6;RH-30: 14.8;SK-BR-3: 7.1" HPA046966 Supported NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA046966: AB_2679879" "prognostic unfavorable (6.86e-4)" "unprognostic (2.59e-1)" "unprognostic (1.06e-1)" "unprognostic (9.12e-2)" "unprognostic (8.58e-3)" "unprognostic (1.63e-3)" "unprognostic (3.88e-2)" "unprognostic (2.03e-2)" "unprognostic (4.02e-2)" "unprognostic (3.98e-2)" "unprognostic (4.21e-2)" "unprognostic (2.99e-1)" "prognostic favorable (8.22e-7)" "unprognostic (5.66e-3)" "unprognostic (9.56e-2)" "unprognostic (4.30e-2)" "unprognostic (1.07e-1)" 0.5 0.0 0.4 12.6 0.6 0.7 1.2 0.5 0.7 25.9 0.5 72.3 47.7 0.3 0.0 158.7 1.3 22.4 0.2 0.4 1.2 9.8 2.3 5.2 0.1 0.8 0.5 0.1 9.1 0.0 0.6 0.1 0.7 2.2 44.5 79.3 84.2 8.5 0.1 3.2 56.3 2.8 0.2 0.2 20.8 4.0 0.6 0.2 0.0 0.0 15.9 3.0 53.2 0.7 46.3 0.0 0.2 0.2 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.1 5.2 0.0 0.6 0.0 0.0 2.0 0.0 0.4 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 6.9 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 20.6 0.0 0.0 14.8 1.6 0.0 0.6 0.0 0.2 0.0 7.1 0.2 0.1 0.1 0.4 0.0 0.2 0.1 0.1 0.3 0.3 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.6 0.5 0.7 0.4 1.2 0.8 0.5 0.7 0.2 0.6 0.7 0.1 0.0 4.8 0.3 1.1 0.0 3.0 23.6 0.0 1.8 1.7 0.3 0.3 11.5 36.4 0.0 0.0 0.1 0.0 154.7 0.0 43.2 4.9 1.1 0.1 0.5 13.8 0.0 0.1 14.2 0.4 0.0 18.3 0.6 8.9 0.1 0.0 0.4 0.0 0.0 0.0 78.7 14.2 0.0 0.0 8.7 0.0 0.2 0.0 1.0 0.0 1.9 0.0 0.0 0.1 49.0 88.9 0.0 0.1 0.9 85.2 16.5 22.8 34.9 0.0 0.0 1.5 0.5 0.2 6.5 0.0 0.3 0.5 0.0 65.6 27.3 FUT6 "FCT3A, FLJ40754, FT1A, FucT-VI" ENSG00000156413 "Fucosyltransferase 6" P51993 19 5830408-5839722 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 79.4;kidney: 36.1;salivary gland: 45.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 35.6;Intestinal goblet cells: 39.4;Paneth cells: 21.5;Proximal enterocytes: 101.4;Proximal tubular cells: 45.3;Undifferentiated cells: 29.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 9.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 6 "Hep G2: 10.5;RPMI-8226: 4.0" "HPA043707, HPA046966" Approved Supported "Golgi apparatus" "Secreted to blood" NA NA 51000 "Cluster 10: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" "HPA043707: AB_2678628, HPA046966: AB_2679879" "unprognostic (3.65e-2)" "unprognostic (3.00e-3)" "unprognostic (2.13e-3)" "unprognostic (2.78e-3)" "unprognostic (6.35e-2)" "prognostic favorable (2.12e-4)" "unprognostic (8.02e-2)" "unprognostic (6.68e-3)" "unprognostic (4.01e-2)" "unprognostic (8.53e-2)" "unprognostic (2.62e-2)" "unprognostic (4.94e-2)" "prognostic favorable (3.17e-8)" "unprognostic (1.05e-2)" "unprognostic (1.38e-1)" "unprognostic (2.40e-1)" "unprognostic (1.27e-1)" 0.1 0.0 0.1 2.6 0.1 0.4 1.7 0.2 0.1 17.3 0.4 17.3 28.6 0.3 0.0 79.4 0.6 9.3 0.0 0.1 0.1 36.1 12.4 0.2 0.1 0.1 0.1 0.0 3.7 0.0 0.0 0.0 0.1 0.2 11.6 2.0 45.7 2.5 0.0 0.1 27.0 0.4 0.1 0.1 4.8 0.2 0.1 0.0 0.0 0.0 6.7 0.0 26.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.2 10.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.7 4.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.6 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.0 0.5 0.0 0.7 0.0 0.4 3.5 0.0 0.4 3.7 1.9 0.3 18.6 15.7 1.8 0.0 0.2 0.3 35.6 3.9 6.8 0.3 0.6 0.7 0.3 4.9 0.0 0.1 0.4 0.1 0.3 0.0 0.7 0.0 0.2 0.7 5.1 0.1 0.0 0.1 39.4 8.2 0.0 0.8 0.0 0.3 0.4 0.0 0.0 0.0 0.9 0.0 0.5 0.1 2.7 21.5 0.0 0.0 0.2 101.4 45.3 6.4 11.5 0.0 0.3 0.7 1.0 0.6 3.6 0.1 0.0 0.5 0.1 29.0 1.7 GALM ENSG00000143891 "Galactose mutarotase" Q96C23 2 38666081-38741237 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 86.5;kidney: 120.2" "Cell type enhanced" "Detected in many" "Peritubular cells: 97.8;Proximal enterocytes: 161.1;Proximal tubular cells: 222.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 68.3" "Group enriched" "Detected in all" 5 "granulocytes: 39.1;T-cells: 68.3" "Cell line enhanced" "Detected in many" "Hep G2: 62.7;Karpas-707: 71.1;U-266/70: 76.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035472, HPA035473, HPA064835" Enhanced Approved Nucleoplasm NA NA 620000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA035472: AB_10669906, HPA035473: AB_2674642, HPA064835: AB_2732723" "unprognostic (5.02e-2)" "unprognostic (1.10e-1)" "unprognostic (2.67e-1)" "unprognostic (9.20e-2)" "unprognostic (1.88e-2)" "unprognostic (9.99e-3)" "unprognostic (1.63e-2)" "unprognostic (2.80e-3)" "unprognostic (1.87e-1)" "unprognostic (7.17e-2)" "unprognostic (6.65e-2)" "unprognostic (6.45e-2)" "prognostic favorable (9.06e-5)" "unprognostic (1.70e-2)" "unprognostic (1.62e-1)" "unprognostic (4.34e-1)" "prognostic favorable (1.32e-4)" 9.0 86.5 5.2 12.2 5.1 3.8 10.4 6.0 6.1 9.3 8.3 34.7 71.4 8.1 23.0 5.8 35.8 16.5 13.0 4.9 4.8 120.2 72.5 14.3 16.0 5.4 6.1 15.5 15.0 21.3 3.0 7.7 5.4 10.2 33.3 4.4 8.7 20.8 13.1 3.8 52.8 10.4 5.7 6.6 14.9 4.4 7.0 11.0 15.1 12.3 10.2 10.8 6.4 6.0 0.2 27.1 8.1 0.0 27.3 15.4 14.9 3.2 10.3 7.5 12.2 32.4 14.4 10.9 18.9 15.3 14.5 4.3 11.7 0.7 14.5 49.5 19.3 5.9 7.1 62.7 10.0 2.4 0.4 11.1 0.4 17.5 0.0 10.5 8.2 0.0 17.2 71.1 13.9 0.9 23.4 41.0 12.4 59.2 8.6 15.2 0.6 21.3 9.3 45.1 1.5 11.2 0.1 18.9 14.7 10.2 9.0 5.4 3.4 2.5 0.5 18.6 1.0 76.4 54.3 0.3 17.9 7.0 0.3 39.1 4.8 4.2 21.5 3.3 31.8 6.8 33.1 31.2 10.3 4.7 11.7 10.2 11.3 5.5 0.7 0.8 68.3 11.9 5.2 5.1 6.0 6.1 4.9 4.8 5.4 6.1 5.4 5.7 7.0 6.0 9.7 28.9 11.0 13.4 10.0 6.6 6.7 3.4 10.8 3.6 7.8 4.2 23.4 24.3 6.5 69.9 0.0 23.6 19.0 83.2 25.4 12.1 1.4 28.5 11.6 10.0 13.2 8.2 2.3 15.1 31.4 16.1 17.9 10.1 7.0 16.8 14.6 48.1 94.8 3.3 1.4 40.5 4.1 18.6 43.6 1.3 20.2 34.7 17.8 4.7 9.9 38.2 18.6 0.5 1.3 6.8 64.5 97.8 14.7 5.7 161.1 222.1 14.8 6.8 6.6 16.6 10.4 1.0 2.3 3.2 6.0 6.3 44.0 43.3 80.4 5.7 GAMT "PIG2, TP53I2" ENSG00000130005 "Guanidinoacetate N-methyltransferase" Q14353 19 1397026-1401570 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 615.1;skeletal muscle: 1234.9;tongue: 466.4" "Group enriched" "Detected in many" 4 "Hepatocytes: 718.3;Proximal tubular cells: 417.4" "Cancer enriched" "Detected in all" 5 "liver cancer: 173.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 176.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051806 Approved NA NA 420000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA051806: AB_2681619" "unprognostic (3.25e-1)" "unprognostic (7.74e-3)" "unprognostic (3.22e-2)" "unprognostic (6.32e-2)" "unprognostic (4.35e-2)" "unprognostic (1.86e-1)" "unprognostic (2.92e-2)" "unprognostic (2.80e-2)" "unprognostic (1.14e-1)" "unprognostic (2.27e-1)" "unprognostic (3.41e-2)" "unprognostic (7.10e-2)" "unprognostic (6.36e-2)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.78e-1)" "unprognostic (1.82e-1)" "unprognostic (1.54e-2)" 14.0 26.6 69.4 4.5 74.5 8.8 15.6 68.6 79.1 16.5 53.4 10.9 3.2 10.0 141.9 23.0 14.7 9.9 98.1 67.3 67.1 72.0 615.1 8.1 7.7 71.8 68.3 22.8 229.8 37.8 37.4 4.9 70.4 36.5 2.2 15.0 42.6 17.5 1234.9 32.8 6.4 4.6 68.8 10.7 31.8 55.0 76.1 24.8 22.2 466.4 4.3 12.9 15.3 94.5 21.6 24.1 25.2 56.9 30.9 37.3 34.3 25.2 41.2 31.8 28.7 54.8 15.1 11.3 17.2 30.0 3.8 9.1 39.8 15.5 8.5 81.5 46.2 34.9 20.3 176.7 18.2 0.7 11.5 41.8 5.5 33.8 0.1 44.0 6.9 43.0 50.6 26.6 52.6 22.1 103.9 12.0 28.6 10.7 75.4 103.1 22.3 81.4 38.1 19.5 8.4 58.5 1.9 14.3 32.0 16.1 65.3 48.1 12.2 34.6 35.6 1.9 11.6 119.0 24.8 19.5 32.2 46.1 40.7 3.7 2.5 15.3 18.8 3.4 27.3 22.0 26.3 23.8 11.2 32.3 40.6 30.8 1.5 18.2 6.1 47.3 15.8 14.9 69.4 74.5 68.6 79.1 67.3 67.1 71.8 68.3 70.4 68.8 76.1 94.5 9.2 0.0 7.2 5.5 18.0 58.9 42.1 57.8 116.7 41.0 60.3 99.9 99.3 127.2 12.9 16.5 56.3 35.7 15.4 0.8 92.0 39.9 5.2 6.5 7.4 9.2 7.2 35.8 7.4 33.6 41.2 30.9 10.2 4.0 4.5 43.3 18.9 718.3 81.7 18.5 10.1 1.5 6.1 29.5 13.3 16.0 83.9 13.9 32.0 3.7 4.7 57.3 10.3 4.0 36.7 13.5 0.1 139.5 12.5 24.1 0.1 417.4 6.1 61.7 32.9 77.8 47.1 4.3 22.6 42.1 42.9 12.0 19.7 31.1 3.3 23.2 GATM AGAT ENSG00000171766 "Glycine amidinotransferase" P50440 15 45361124-45402327 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 12 "kidney: 2099.3;liver: 2804.2;pancreas: 2935.3" "Group enriched" "Detected in many" 8 "Hepatocytes: 1495.2;Proximal tubular cells: 3703.0" "Cancer enhanced" "Detected in all" "liver cancer: 135.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 11.0;myeloid DC: 6.6;naive B-cell: 5.4;plasmacytoid DC: 6.8" "Group enriched" "Detected in many" 5 "B-cells: 11.0;dendritic cells: 6.8" "Group enriched" "Detected in many" 4 "RH-30: 210.1;RT4: 55.8;U-266/70: 126.3;U-266/84: 165.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026077 Enhanced Supported Mitochondria NA NA 600000 "Cluster 43: B-cells - Humoral immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA026077: AB_1849528" "unprognostic (1.91e-1)" "unprognostic (1.33e-2)" "unprognostic (2.77e-2)" "unprognostic (6.57e-2)" "unprognostic (9.43e-2)" "unprognostic (1.67e-2)" "unprognostic (6.99e-3)" "unprognostic (1.04e-1)" "unprognostic (4.51e-2)" "unprognostic (3.36e-2)" "unprognostic (1.33e-1)" "unprognostic (5.67e-2)" "prognostic favorable (1.38e-4)" "unprognostic (1.09e-1)" "unprognostic (4.07e-2)" "unprognostic (3.60e-2)" "unprognostic (1.80e-1)" 14.4 21.4 133.9 12.4 138.4 1.8 25.4 152.5 216.5 9.9 94.3 19.6 175.5 8.4 10.5 25.1 11.6 47.7 57.2 131.1 140.9 2099.3 2804.2 7.3 18.4 148.0 135.4 165.2 2935.3 2.7 8.3 74.7 153.4 12.4 11.5 7.5 57.5 15.1 142.5 137.6 110.2 14.5 149.2 33.6 99.2 78.2 140.4 12.6 63.0 46.9 29.7 18.0 15.5 181.2 12.9 6.5 4.4 0.6 0.1 0.2 0.8 0.1 0.1 0.0 0.2 1.4 21.4 34.4 1.0 0.0 5.7 2.2 17.0 0.6 0.4 1.9 0.3 2.8 0.4 0.3 0.8 20.7 2.6 0.8 0.7 0.0 0.4 0.0 0.3 7.8 0.4 0.7 0.2 0.6 2.2 0.6 11.2 31.3 0.0 0.5 210.1 1.5 3.5 55.8 23.5 4.1 6.9 0.4 1.2 2.1 2.9 23.7 0.0 0.0 0.5 0.2 6.3 126.3 165.5 0.8 1.6 0.3 1.0 0.0 1.1 0.3 0.2 1.6 0.0 11.0 0.0 0.2 6.6 5.4 0.0 1.4 0.0 0.1 0.6 6.8 0.0 1.0 133.9 138.4 152.5 216.5 131.1 140.9 148.0 135.4 153.4 149.2 140.4 181.2 2.4 3.2 1.1 67.3 42.3 54.3 14.9 5.2 5.7 8.1 16.9 9.5 35.5 228.8 5.4 71.7 0.0 1.0 0.8 3.1 295.4 58.2 8.8 1.3 0.4 7.3 0.0 29.3 6.8 290.0 1.2 19.8 69.8 2.7 3.8 219.5 23.9 1495.2 89.6 8.4 3.3 3.1 2.0 80.3 80.3 18.3 4.4 50.6 23.2 20.6 3.1 19.1 2.1 57.3 196.3 97.3 3.9 3.4 7.2 6.4 98.4 3703.0 1.9 3.8 6.6 38.4 16.8 22.0 9.7 16.0 133.7 1.8 17.6 4.1 3.4 20.4 GCHFR "GFRP, HsT16933" ENSG00000137880 "GTP cyclohydrolase I feedback regulator" P30047 15 40764068-40767708 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 350.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 787.2;Hofbauer cells: 522.9;Proximal enterocytes: 620.8;Proximal tubular cells: 500.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 120.3;RPTEC TERT1: 146.6;SCLC-21H: 124.6" "Group enriched" "Detected in many" 5 "cerebellum: 10.3;midbrain: 11.8;pons and medulla: 9.4" HPA046258 Enhanced Supported Nucleoplasm NA NA 170000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "HPA046258: AB_10967205" "unprognostic (2.50e-1)" "unprognostic (1.49e-2)" "unprognostic (1.28e-1)" "unprognostic (1.72e-2)" "unprognostic (9.89e-3)" "unprognostic (3.51e-3)" "unprognostic (1.57e-1)" "prognostic favorable (5.62e-4)" "unprognostic (4.63e-2)" "unprognostic (1.67e-1)" "unprognostic (3.81e-1)" "unprognostic (2.31e-1)" "unprognostic (7.03e-3)" "unprognostic (9.28e-3)" "unprognostic (2.91e-2)" "unprognostic (1.84e-1)" "unprognostic (2.55e-1)" 37.4 20.1 13.6 8.9 13.3 19.5 34.5 17.4 20.1 16.1 18.5 18.7 38.8 6.5 2.2 57.2 15.8 10.0 10.9 13.1 14.5 73.5 350.1 46.4 24.7 18.2 67.3 19.2 15.3 9.8 12.2 6.6 33.7 19.4 6.9 4.2 22.3 3.2 4.5 31.1 60.7 1.7 13.5 13.0 16.4 3.3 15.9 23.0 12.8 7.4 19.5 12.2 17.6 12.2 0.3 7.7 6.2 33.3 9.5 3.4 16.7 2.2 7.8 3.7 7.4 90.7 49.7 46.0 31.1 1.9 2.4 6.1 16.4 3.1 0.8 36.2 26.2 45.5 65.3 120.3 7.7 29.9 15.2 7.8 3.8 1.6 0.6 2.9 14.4 3.7 23.2 13.2 1.1 17.2 7.9 60.4 16.0 8.2 56.5 64.7 0.5 28.8 146.6 24.2 124.6 1.9 20.1 87.7 10.4 8.1 25.3 30.0 0.0 0.6 1.2 2.2 0.3 0.9 6.0 28.9 4.9 66.3 4.0 18.0 73.3 102.4 76.8 23.6 129.0 48.2 67.1 71.1 48.7 31.2 68.3 44.7 11.7 132.6 22.4 90.4 144.4 109.0 13.6 13.3 17.4 20.1 13.1 14.5 18.2 67.3 33.7 13.5 15.9 12.2 24.3 3.2 54.0 0.3 24.9 14.5 21.6 72.2 8.6 2.5 81.4 48.0 0.1 84.4 87.0 64.4 12.5 161.9 25.9 75.7 76.3 52.5 0.6 46.2 4.9 13.7 60.6 24.4 1.6 32.7 37.0 10.1 16.3 35.7 44.4 12.2 31.4 787.2 522.9 0.0 1.7 74.4 111.9 56.1 18.5 0.5 17.7 71.9 67.6 0.0 29.0 26.1 102.0 0.0 0.4 18.7 161.8 8.6 12.8 25.6 620.8 500.2 58.3 22.4 0.0 4.7 12.4 2.9 12.5 79.7 14.9 36.5 49.2 1.7 125.3 40.8 GDA ENSG00000119125 "Guanine deaminase" Q9Y2T3 9 72114595-72257193 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 79.7;intestine: 94.8;kidney: 42.9;liver: 60.3" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 112.3;Excitatory neurons: 109.3;Glandular and luminal cells: 171.1;Paneth cells: 83.7;Proximal enterocytes: 321.3;Proximal tubular cells: 98.2" "Cancer enhanced" "Detected in many" "renal cancer: 13.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 34.4;EFO-21: 127.9;HeLa: 46.4;hTCEpi: 62.3;OE19: 157.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "amygdala: 36.5;basal ganglia: 30.1;cerebral cortex: 60.0;hippocampal formation: 70.7;olfactory bulb: 18.3" "HPA019352, HPA024099, HPA030387" Enhanced Approved Nucleoplasm No NA 1500000 "Cluster 11: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA019352: AB_1855593, HPA024099: AB_1855594, HPA030387: AB_10602351" "unprognostic (2.64e-2)" "unprognostic (7.10e-2)" "unprognostic (2.83e-2)" "unprognostic (2.92e-1)" "unprognostic (4.35e-2)" "unprognostic (8.45e-2)" "unprognostic (2.00e-1)" "unprognostic (5.60e-2)" "unprognostic (3.26e-1)" "unprognostic (1.32e-1)" "unprognostic (1.55e-1)" "unprognostic (5.56e-2)" "prognostic favorable (2.66e-5)" "unprognostic (2.23e-1)" "unprognostic (6.70e-2)" "unprognostic (2.77e-1)" "unprognostic (8.30e-4)" 0.3 2.7 57.0 1.2 66.9 0.4 0.2 19.8 79.7 1.6 23.2 10.4 94.3 3.7 0.4 0.4 8.5 15.9 0.1 62.3 52.3 42.9 60.3 0.2 0.4 19.9 26.1 0.2 2.7 8.5 2.8 2.9 25.8 0.1 9.9 0.1 0.0 6.7 1.6 2.2 94.8 0.4 20.5 0.1 3.4 1.2 60.5 0.6 0.1 0.4 4.7 4.0 0.2 42.3 34.4 4.5 0.1 0.1 0.0 0.0 0.8 0.3 24.9 0.0 0.0 3.2 19.3 0.0 127.9 0.0 0.2 2.9 0.2 0.0 0.0 0.4 0.1 0.0 46.4 0.2 0.0 0.1 0.1 0.2 62.3 0.0 0.6 0.1 0.0 0.0 9.6 0.1 0.0 0.2 0.2 0.3 0.2 157.0 0.0 0.0 0.1 1.1 1.1 7.9 0.2 0.6 2.5 0.1 0.1 0.2 0.1 0.2 0.6 0.2 0.4 0.2 0.1 0.3 0.2 0.3 0.1 0.3 0.1 0.8 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.1 0.2 0.4 0.3 0.1 0.1 0.1 0.0 57.0 66.9 19.8 79.7 62.3 52.3 19.9 26.1 25.8 20.5 60.5 42.3 0.0 0.0 0.5 3.9 1.9 0.0 0.7 19.0 0.0 0.0 0.0 0.0 0.8 14.3 24.7 0.0 0.0 0.2 0.0 65.5 3.9 11.7 1.2 112.3 7.4 0.4 4.8 0.0 109.3 10.7 1.9 0.3 12.2 171.1 0.0 0.0 1.1 56.9 0.2 0.0 22.8 22.1 2.0 1.9 0.4 0.6 0.3 1.2 0.0 5.6 0.6 0.0 0.0 5.0 3.8 6.7 83.7 0.0 0.1 0.8 321.3 98.2 58.6 0.0 0.0 0.8 3.0 1.4 4.7 0.0 0.1 1.9 1.2 0.2 16.1 2.2 GGH ENSG00000137563 "Gamma-glutamyl hydrolase" Q92820 8 63014881-63039407 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 125.7;liver: 188.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 510.3;Early spermatids: 471.0;Extravillous trophoblasts: 273.4;Proximal tubular cells: 340.8;Syncytiotrophoblasts: 754.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 30.6" "Lineage enriched" "Detected in all" 5 "dendritic cells: 30.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019296, HPA025226" Approved "Intracellular and membrane" NA NA 1200000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB019296: , HPA025226: AB_1849645" "unprognostic (9.29e-2)" "unprognostic (1.22e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (3.99e-7)" "unprognostic (5.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.65e-4)" "unprognostic (1.95e-2)" "unprognostic (1.60e-1)" "unprognostic (2.11e-2)" "unprognostic (1.32e-1)" "unprognostic (1.69e-2)" "unprognostic (9.62e-3)" "unprognostic (1.50e-1)" "unprognostic (2.36e-1)" "unprognostic (6.50e-2)" 9.8 5.4 11.1 14.2 11.1 43.7 16.5 10.7 14.3 5.9 13.1 54.3 11.3 6.3 4.4 20.7 3.5 4.3 3.1 11.1 12.3 125.7 188.6 8.0 10.9 13.3 11.1 3.1 9.9 13.1 1.9 54.9 13.7 4.4 74.4 2.1 13.0 3.7 2.1 27.2 9.9 11.6 10.1 5.5 8.2 33.9 14.4 17.8 2.4 3.2 22.5 8.5 10.8 11.1 110.5 97.6 97.4 15.7 94.1 39.6 69.6 64.3 105.1 94.2 137.7 144.5 183.8 69.8 18.0 77.1 166.8 87.2 97.2 101.9 138.9 139.0 71.6 112.3 50.3 105.1 17.6 53.5 65.9 29.1 29.2 93.9 50.7 59.4 116.1 66.9 62.4 255.2 177.3 64.3 28.8 71.1 51.0 231.6 86.0 77.6 95.2 98.1 75.8 40.3 38.6 69.9 91.8 103.6 98.5 91.6 116.6 65.8 65.5 104.2 115.6 99.4 111.3 112.6 127.2 88.3 158.0 0.1 185.0 0.0 2.1 2.3 1.1 1.7 0.8 6.5 1.5 1.7 0.9 2.7 1.8 1.9 3.0 4.4 2.0 30.6 2.7 1.9 11.1 11.1 10.7 14.3 11.1 12.3 13.3 11.1 13.7 10.1 14.4 11.1 13.1 16.0 7.3 11.1 26.1 30.2 23.2 66.6 9.1 2.0 14.9 21.0 3.2 17.2 31.1 22.0 0.0 510.3 11.7 49.2 37.2 19.7 471.0 5.4 11.5 13.1 13.2 62.5 11.5 7.4 273.4 27.2 11.7 7.6 10.8 21.4 13.6 219.5 72.4 0.0 8.7 70.7 44.7 21.0 15.5 154.2 5.9 12.0 24.9 1.0 32.1 23.1 2.1 3.5 2.9 4.3 23.7 8.2 106.9 10.5 4.3 340.8 18.3 1.3 26.3 12.8 20.4 80.3 133.0 35.9 43.0 754.5 8.5 9.3 102.0 23.1 GHRHR ENSG00000106128 "Growth hormone releasing hormone receptor" Q02643 7 30938669-30993254 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 351 "pituitary gland: 211.7" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1.5;Spermatocytes: 1.2;Spermatogonia: 3.0" "Cancer enhanced" "Detected in single" "liver cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "unprognostic (8.32e-2)" "unprognostic (1.45e-1)" "unprognostic (9.30e-2)" "unprognostic (1.39e-1)" "unprognostic (7.23e-2)" "unprognostic (4.15e-1)" "unprognostic (2.28e-2)" "unprognostic (1.54e-1)" "unprognostic (1.20e-1)" "unprognostic (1.27e-1)" "unprognostic (1.43e-2)" "unprognostic (1.47e-1)" "unprognostic (5.87e-3)" 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 211.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.1 1.2 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GIPC2 "FLJ20075, SEMCAP-2" ENSG00000137960 "GIPC PDZ domain containing family member 2" Q8TF65 1 77979542-78138444 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.0;kidney: 41.4;lymphoid tissue: 27.9" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 122.1;Proximal tubular cells: 267.7;Undifferentiated cells: 63.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 6.1;HaCaT: 6.0;Hep G2: 23.0;HUVEC TERT2: 23.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA051212, HPA062684" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Cytosol "HPA051212: , HPA062684: AB_2684833" "unprognostic (1.72e-2)" "unprognostic (9.37e-2)" "prognostic favorable (5.49e-4)" "unprognostic (1.09e-2)" "unprognostic (1.43e-1)" "unprognostic (2.29e-2)" "unprognostic (2.01e-1)" "unprognostic (2.35e-1)" "unprognostic (7.63e-2)" "unprognostic (2.22e-1)" "unprognostic (5.91e-2)" "unprognostic (1.44e-1)" "prognostic favorable (2.11e-6)" "unprognostic (6.55e-2)" "unprognostic (1.78e-1)" "unprognostic (4.18e-2)" "unprognostic (1.29e-1)" 3.9 23.8 0.5 1.7 0.4 0.3 3.0 0.4 0.5 1.8 0.5 15.6 38.0 2.1 0.9 2.1 3.1 5.5 1.5 0.5 0.4 41.4 18.4 2.7 0.8 0.4 0.4 2.4 18.1 2.3 0.9 3.5 0.4 1.7 14.9 0.1 4.2 0.9 1.1 4.7 38.0 2.8 0.4 27.9 6.0 1.0 0.5 0.4 1.0 1.6 0.8 2.0 1.9 0.4 0.0 0.0 0.0 0.1 2.4 6.1 0.0 1.0 0.0 0.5 1.1 5.1 3.3 1.5 0.1 0.5 0.0 6.0 0.0 0.0 3.2 0.2 0.0 0.8 0.0 23.0 1.2 0.0 0.0 1.0 0.1 3.5 0.1 0.0 23.5 0.0 0.0 0.1 2.9 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.4 0.5 0.5 0.4 0.4 0.4 0.4 0.4 0.5 0.4 33.6 0.0 1.3 2.0 2.0 12.9 2.4 0.9 4.0 0.4 5.2 1.5 3.2 27.1 2.5 9.2 2.1 6.7 0.0 43.7 33.2 11.8 2.5 13.3 0.9 21.6 3.0 0.4 14.7 33.0 3.1 2.9 8.6 7.2 0.0 5.9 22.9 43.3 13.2 0.0 15.2 34.4 0.0 0.8 1.9 1.2 1.2 2.1 0.0 14.0 1.0 0.0 0.0 4.5 8.9 16.5 39.3 0.0 0.0 0.8 122.1 267.7 11.7 0.5 0.0 1.3 1.3 0.6 2.5 7.9 21.7 1.6 1.3 32.4 63.8 6.0 GJA3 "CX46, CZP3" ENSG00000121743 "Gap junction protein alpha 3" Q9Y6H8 13 20138255-20161052 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 7.8;parathyroid gland: 4.0;placenta: 2.5" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 13.6" "Group enriched" "Detected in some" 4 "head and neck cancer: 1.3;melanoma: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 4.4;CAPAN-2: 7.7;HL-60: 6.6;U-266/84: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA014821 Supported NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA014821: AB_2669097" "unprognostic (2.32e-1)" "unprognostic (1.01e-1)" "unprognostic (4.37e-2)" "unprognostic (2.58e-3)" "unprognostic (2.98e-2)" "unprognostic (1.04e-2)" "unprognostic (6.87e-3)" "unprognostic (1.84e-1)" "unprognostic (1.73e-1)" "unprognostic (7.52e-2)" "unprognostic (7.70e-2)" "unprognostic (4.02e-2)" "unprognostic (9.65e-8)" "unprognostic (2.87e-1)" "unprognostic (1.91e-1)" "unprognostic (2.55e-2)" "unprognostic (8.04e-3)" 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 7.8 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 4.0 0.0 2.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 1.2 0.1 0.0 0.1 0.0 1.0 0.0 0.2 0.0 4.4 0.2 0.0 3.7 0.1 1.1 0.0 0.5 3.5 0.6 0.7 0.4 7.7 0.0 0.1 1.3 1.2 0.1 2.5 2.1 0.5 0.2 1.9 1.8 0.0 0.0 0.0 6.6 0.0 0.2 1.2 0.1 0.3 0.0 0.0 2.8 0.5 0.0 0.1 0.0 0.0 0.0 0.5 0.1 1.5 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 3.7 0.1 0.8 1.4 0.0 0.0 0.0 1.5 0.2 1.7 4.7 0.0 0.0 0.1 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 1.2 0.0 0.0 0.0 13.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 2.7 0.3 0.0 0.0 0.1 0.0 0.0 0.1 GJB2 "CX26, DFNA3, DFNB1, NSRD1" ENSG00000165474 "Gap junction protein beta 2" P29033 13 20187463-20192938 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Hearing "Deafness, Disease variant, Ectodermal dysplasia, Ichthyosis, Non-syndromic deafness, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 328.1;esophagus: 812.1;vagina: 519.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 69.8;Basal respiratory cells: 237.4;Basal squamous epithelial cells: 55.8;Ionocytes: 50.8;Squamous epithelial cells: 160.9" "Cancer enhanced" "Detected in all" "head and neck cancer: 447.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 144.6;hTCEpi: 105.4;OE19: 76.9;RT4: 169.9" "Low region specificity" "Detected in all" "CAB013093, HPA014362" Uncertain Approved Mitochondria NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "CAB013093: AB_2533903, HPA014362: " "unprognostic (2.21e-1)" "unprognostic (1.25e-3)" "unprognostic (2.43e-2)" "unprognostic (6.14e-2)" "prognostic unfavorable (4.45e-4)" "unprognostic (9.77e-2)" "unprognostic (2.92e-1)" "prognostic unfavorable (6.25e-4)" "unprognostic (1.33e-1)" "unprognostic (3.69e-3)" "prognostic unfavorable (2.90e-4)" "unprognostic (3.22e-2)" "prognostic unfavorable (2.53e-6)" "unprognostic (5.78e-3)" "unprognostic (2.40e-1)" "unprognostic (1.17e-2)" "unprognostic (8.93e-3)" 2.0 0.7 1.3 6.7 1.2 3.8 3.7 2.4 3.1 328.1 5.3 20.8 12.9 2.9 3.4 812.1 0.9 14.0 0.4 1.1 1.7 9.8 47.5 0.7 0.4 1.8 1.7 0.3 1.3 0.1 4.1 0.2 1.7 1.2 17.4 0.0 145.2 0.3 0.4 73.0 10.6 2.6 1.7 0.2 8.1 1.2 7.6 12.5 1.7 1.2 90.4 27.9 519.8 1.6 8.7 0.6 0.0 0.2 0.0 2.9 1.7 0.0 0.0 0.0 0.0 1.3 144.6 0.0 0.7 0.1 1.1 28.9 5.3 14.4 0.1 12.6 1.8 0.1 0.1 0.3 0.0 0.0 5.1 2.4 105.4 1.9 19.5 0.0 0.0 2.1 0.1 10.7 0.2 1.4 1.3 0.0 0.3 76.9 14.4 0.2 0.0 8.3 0.2 169.9 0.1 0.0 0.3 0.1 0.3 1.9 2.2 0.4 0.0 0.2 0.0 2.5 22.2 8.7 9.6 0.0 17.1 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 2.4 3.1 1.1 1.7 1.8 1.7 1.7 1.7 7.6 1.6 0.1 3.2 0.0 2.0 0.6 69.8 16.1 237.4 55.8 0.0 1.3 1.3 0.5 4.3 37.3 1.8 0.0 0.1 0.0 28.0 0.0 4.4 1.5 5.0 1.5 1.3 4.2 0.0 0.0 9.8 0.2 1.7 4.1 19.1 0.0 0.0 0.0 25.2 0.6 0.0 0.0 6.1 50.8 0.6 13.3 1.3 0.0 3.9 1.8 0.0 4.6 0.0 0.0 0.0 0.0 9.2 13.3 0.0 2.7 8.6 10.7 17.5 7.5 0.0 0.0 0.1 4.7 0.8 2.1 160.9 28.7 0.1 0.9 0.0 25.0 21.7 GK "GK1, GKD" ENSG00000198814 "Glycerol kinase" P32189 X 30653359-30731462 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 90.7;kidney: 107.7;liver: 79.2" "Cell type enhanced" "Detected in many" "Langerhans cells: 139.2;Macrophages: 133.4;Proximal enterocytes: 144.2;Proximal tubular cells: 161.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 8 "neutrophil: 178.4" "Lineage enriched" "Detected in all" 8 "granulocytes: 178.4" "Cell line enhanced" "Detected in many" "BJ hTERT+: 37.4;Hep G2: 46.4" "Low region specificity" "Detected in all" HPA060687 Supported NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 41: Macrophages - Immune response" "HPA060687: AB_2684343" "unprognostic (8.78e-3)" "unprognostic (8.41e-3)" "unprognostic (1.28e-2)" "unprognostic (3.77e-2)" "unprognostic (3.15e-1)" "unprognostic (4.15e-3)" "unprognostic (5.52e-2)" "unprognostic (1.42e-2)" "unprognostic (3.85e-1)" "unprognostic (8.56e-3)" "unprognostic (1.30e-2)" "unprognostic (1.58e-2)" "prognostic favorable (3.24e-9)" "unprognostic (1.59e-1)" "unprognostic (9.35e-2)" "unprognostic (4.57e-3)" "unprognostic (4.11e-3)" 8.8 9.8 3.1 51.5 2.8 6.6 4.8 3.7 17.2 4.8 8.4 13.0 86.6 3.6 12.3 9.6 7.7 23.8 4.8 2.3 4.1 107.7 79.2 19.7 10.6 7.2 4.2 2.6 4.5 14.0 5.4 8.2 6.8 3.6 10.9 10.3 11.2 2.2 2.6 6.3 90.7 4.4 3.6 10.1 6.2 2.9 14.5 5.4 6.6 3.1 14.5 30.2 2.7 8.0 4.5 3.5 4.5 7.7 2.7 10.4 1.8 10.6 37.4 7.6 8.6 5.8 4.1 12.6 1.7 4.1 6.9 0.3 8.5 3.5 10.1 8.2 9.6 7.5 6.6 46.4 17.2 14.2 15.4 6.3 4.9 24.2 22.3 1.9 6.0 9.6 4.0 17.3 2.1 6.2 11.0 14.6 7.5 4.9 4.0 15.0 7.1 13.1 5.7 14.8 4.8 6.1 9.4 9.4 21.5 4.5 10.6 10.1 2.3 5.5 2.3 0.3 4.9 9.1 10.7 12.5 9.5 9.1 5.6 5.0 22.8 7.9 1.7 7.2 1.3 3.1 3.1 2.2 14.2 5.6 1.8 1.9 178.4 4.8 9.1 4.2 11.5 6.2 3.1 2.8 3.7 17.2 2.3 4.1 7.2 4.2 6.8 3.6 14.5 8.0 2.0 16.0 27.4 19.6 15.8 6.9 12.3 12.6 4.6 3.2 9.4 3.9 4.3 12.8 22.5 7.3 16.7 1.2 5.6 54.7 35.2 21.9 61.5 15.1 2.7 3.8 12.1 6.3 41.5 11.1 1.1 12.4 20.9 1.7 14.5 6.9 3.6 38.1 34.8 5.0 37.2 14.7 0.0 26.6 139.2 29.9 1.2 133.4 14.2 10.3 42.6 29.1 3.1 28.6 19.6 10.6 39.9 2.2 12.4 17.0 144.2 161.1 47.7 17.7 0.0 9.2 7.0 15.3 1.7 14.7 16.9 0.8 15.7 3.7 11.0 26.8 GLB1L3 FLJ90231 ENSG00000166105 "Galactosidase beta 1 like 3" Q8NCI6 11 134274245-134319564 "Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.0;prostate: 7.9;seminal vesicle: 4.3" "Cell type enhanced" "Detected in some" "Early spermatids: 9.8;Excitatory neurons: 39.5;Inhibitory neurons: 20.9;Oligodendrocyte precursor cells: 11.6;Spermatogonia: 7.5" "Cancer enhanced" "Detected in some" "prostate cancer: 5.0" "Region enhanced" "Detected in some" "cerebral cortex: 4.0" "Group enriched" "Detected in many" 11 "gdT-cell: 1.2;memory CD4 T-cell: 3.1;memory CD8 T-cell: 1.9;naive CD4 T-cell: 2.4;naive CD8 T-cell: 1.9;T-reg: 1.5" "Lineage enriched" "Detected in single" 31 "T-cells: 3.1" "Cell line enhanced" "Detected in some" "HEK 293: 5.5;JURKAT: 11.4;NTERA-2: 3.4;PC-3: 4.5;SCLC-21H: 6.8" "Not detected" "Not detected" HPA039916 Uncertain NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 68: Epididymis - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA039916: AB_2676746" "unprognostic (1.64e-3)" "unprognostic (7.80e-3)" "unprognostic (5.12e-2)" "unprognostic (1.27e-1)" "unprognostic (1.35e-1)" "unprognostic (1.55e-2)" "unprognostic (8.69e-3)" "prognostic favorable (1.97e-4)" "unprognostic (6.58e-3)" "unprognostic (3.81e-1)" "unprognostic (6.95e-3)" "unprognostic (9.73e-2)" "unprognostic (1.52e-5)" "unprognostic (1.39e-1)" "unprognostic (6.40e-2)" "unprognostic (1.52e-1)" "unprognostic (2.07e-1)" 0.0 1.0 0.9 0.4 1.0 0.1 0.3 2.3 4.0 0.4 0.0 0.9 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.4 0.0 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.2 7.9 0.0 1.6 2.7 4.3 0.0 3.3 0.1 0.0 0.0 0.1 0.0 1.3 0.2 0.1 1.3 0.0 0.1 0.1 0.8 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.2 0.0 2.1 5.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 2.2 0.0 3.4 0.0 4.5 0.0 0.0 0.0 0.0 0.0 6.8 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 3.1 1.9 0.0 0.0 2.4 1.9 0.0 0.0 0.0 0.0 1.5 0.6 0.9 1.0 2.3 4.0 0.4 0.1 0.5 0.0 0.2 0.0 0.2 0.8 0.0 0.0 0.0 1.3 0.1 0.5 0.1 1.3 0.0 0.5 0.4 1.3 0.7 0.0 0.1 0.0 0.0 1.3 0.3 0.0 0.0 0.0 9.8 0.1 0.3 0.3 0.0 0.0 39.5 0.0 3.4 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.4 0.0 20.9 0.0 0.0 0.0 0.0 1.2 0.6 0.1 0.0 1.9 0.0 0.3 0.0 11.6 0.9 0.1 0.0 0.0 0.3 0.4 0.0 0.5 0.0 0.7 0.0 0.0 0.1 4.3 7.5 0.0 0.1 1.2 0.3 0.0 0.0 0.1 GLIS1 FLJ36155 ENSG00000174332 "GLIS family zinc finger 1" Q8NBF1 1 53506237-53738106 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 8.1;seminal vesicle: 7.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.6;Excitatory neurons: 28.0;Inhibitory neurons: 13.3;Proximal tubular cells: 4.8" "Cancer enhanced" "Detected in some" "renal cancer: 4.0" "Region enhanced" "Detected in some" "cerebral cortex: 2.2;hippocampal formation: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 4.5;GAMG: 5.9;hTERT-RPE1: 4.7;PC-3: 7.3;U-138 MG: 5.1" "Not detected" "Not detected" HPA001409 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Mitochondria, Cytosol" "HPA001409: AB_1078974" "unprognostic (1.30e-1)" "unprognostic (1.46e-1)" "unprognostic (2.07e-1)" "unprognostic (5.31e-2)" "unprognostic (3.67e-2)" "unprognostic (1.54e-2)" "unprognostic (8.91e-3)" "unprognostic (1.92e-1)" "unprognostic (2.27e-3)" "unprognostic (2.30e-1)" "unprognostic (3.03e-2)" "unprognostic (1.15e-2)" "unprognostic (1.93e-1)" "unprognostic (4.06e-2)" "unprognostic (1.55e-1)" "unprognostic (6.37e-4)" "unprognostic (1.98e-4)" 1.0 0.1 0.5 0.4 0.5 0.0 1.2 0.2 2.2 5.1 0.0 0.3 0.3 0.9 0.5 0.8 0.8 0.6 1.0 2.2 0.0 4.3 0.0 0.2 0.1 0.1 0.1 0.6 0.0 0.1 0.1 0.0 0.0 8.1 0.0 0.0 0.8 7.6 0.1 2.0 0.6 0.2 0.1 0.2 0.8 2.3 0.0 0.2 0.4 0.0 0.0 2.6 4.6 0.3 0.0 0.0 0.0 0.4 2.8 3.7 0.0 2.0 4.5 1.7 1.3 0.0 0.0 0.0 0.1 2.1 5.9 0.0 0.0 0.0 0.5 0.0 1.3 0.0 1.4 0.1 1.0 0.0 0.0 2.5 0.2 2.1 2.0 4.7 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 7.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.9 0.1 1.3 0.0 0.0 3.1 0.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.2 2.2 2.2 0.0 0.1 0.1 0.0 0.1 0.0 0.3 0.2 0.0 0.0 1.3 0.1 6.6 0.0 0.0 4.0 1.3 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.2 0.1 0.0 0.0 28.0 0.0 0.0 3.8 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 1.0 2.9 0.3 0.0 3.6 1.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 1.2 0.1 0.1 0.0 4.8 0.0 0.0 0.0 0.4 0.8 1.8 2.8 0.3 1.7 0.1 0.1 0.1 0.0 0.1 GLOD5 ENSG00000171433 "Glyoxalase domain containing 5" A6NK44 X 48761747-48773648 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "epididymis: 5.8;intestine: 10.6;kidney: 11.2;liver: 8.2" "Group enriched" "Detected in some" 4 "Proximal enterocytes: 45.2;Proximal tubular cells: 70.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "MCF7: 2.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA010667 Enhanced Uncertain Mitochondria NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA010667: AB_1078975" "unprognostic (1.03e-1)" "unprognostic (2.61e-1)" "unprognostic (7.78e-2)" "unprognostic (7.04e-2)" "unprognostic (3.14e-1)" "unprognostic (6.11e-2)" "unprognostic (1.80e-2)" "unprognostic (2.64e-1)" "unprognostic (2.76e-1)" "unprognostic (2.21e-1)" "unprognostic (1.05e-8)" "unprognostic (2.08e-2)" "unprognostic (1.73e-1)" "unprognostic (5.07e-2)" "unprognostic (6.79e-4)" 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.1 0.3 0.0 4.7 10.6 0.0 5.8 0.1 1.9 0.8 0.0 0.0 0.0 11.2 8.2 1.3 0.0 0.1 0.0 0.0 0.7 0.1 0.3 0.0 0.1 0.2 6.1 1.9 0.3 0.3 0.0 0.0 10.0 0.1 0.0 0.0 1.4 0.1 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 3.2 2.6 1.3 0.5 0.0 0.3 0.2 0.0 0.6 8.3 1.0 0.0 4.3 0.3 7.3 0.0 0.1 0.0 14.4 13.7 0.6 0.2 3.0 0.1 0.0 1.2 2.7 0.2 0.9 0.1 0.0 0.0 1.1 0.0 0.1 0.0 8.0 0.0 0.0 0.3 7.3 0.0 0.3 0.0 0.2 0.0 0.5 0.0 0.0 0.6 0.5 0.0 0.5 0.5 0.8 13.9 0.0 0.1 0.3 45.2 70.5 2.7 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 8.9 0.7 GLRX "GRX, GRX1" ENSG00000173221 Glutaredoxin P35754 5 95751319-95822726 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 777.4" "Cell type enhanced" "Detected in many" "Distal tubular cells: 723.9;Extravillous trophoblasts: 751.2;Proximal enterocytes: 968.3;Proximal tubular cells: 1165.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 569.0;RPTEC TERT1: 462.1;U-87 MG: 441.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008634, HPA046431, CAB069419" Approved Supported "Plasma membrane,Cytosol" NA NA 6300000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cytosol" "CAB008634: AB_1616672, CAB069419: AB_1616670, HPA046431: AB_2679663" "unprognostic (1.69e-1)" "unprognostic (1.32e-1)" "unprognostic (1.94e-2)" "unprognostic (4.81e-2)" "unprognostic (2.01e-2)" "unprognostic (2.22e-2)" "unprognostic (8.62e-3)" "unprognostic (9.31e-3)" "unprognostic (1.99e-2)" "unprognostic (1.65e-2)" "unprognostic (2.34e-1)" "unprognostic (1.82e-1)" "unprognostic (8.11e-2)" "unprognostic (2.18e-1)" "unprognostic (1.03e-1)" "unprognostic (2.61e-1)" "unprognostic (2.61e-1)" 82.1 101.4 32.5 80.0 34.9 173.7 37.2 46.3 52.4 28.2 29.0 57.2 194.7 12.7 10.1 13.6 17.2 50.8 102.7 47.3 37.1 247.4 143.6 71.9 61.5 52.0 42.1 10.9 10.9 82.4 23.7 102.0 39.8 28.5 47.4 6.9 59.2 25.6 777.4 38.3 170.3 25.7 34.3 64.9 40.2 4.9 43.6 75.6 18.9 55.9 80.4 53.1 20.9 37.9 22.2 97.1 8.4 18.0 211.3 310.4 1.6 326.5 569.0 35.9 62.9 31.2 10.2 86.2 45.7 99.0 83.0 9.7 12.9 156.4 100.5 75.7 24.1 62.8 63.5 248.1 386.6 67.2 182.8 184.4 23.2 219.7 21.3 81.1 75.3 179.3 8.2 51.3 262.3 7.9 121.4 133.0 22.2 3.3 111.6 186.1 66.8 107.9 462.1 16.8 23.6 12.5 85.3 47.8 39.4 22.0 13.0 66.0 78.0 91.9 101.9 74.6 14.4 37.1 202.0 70.4 441.3 170.6 19.7 48.9 727.2 901.6 222.9 483.8 313.6 142.9 205.0 166.7 459.8 107.8 201.4 186.1 783.8 113.4 411.2 166.6 457.7 781.7 32.5 34.9 46.3 52.4 47.3 37.1 52.0 42.1 39.8 34.3 43.6 37.9 77.5 22.4 28.4 3.6 74.1 17.2 62.9 330.5 8.6 2.2 57.9 31.5 154.9 65.8 183.6 93.8 0.0 47.4 130.0 173.8 723.9 60.4 0.3 83.4 49.0 47.1 31.7 63.1 8.7 96.0 751.2 63.1 35.7 118.0 31.6 3.5 46.4 206.9 271.5 0.0 8.0 89.9 65.1 304.9 276.1 2.3 19.0 232.3 69.4 12.2 340.0 7.8 302.8 2.0 2.4 113.5 291.3 13.9 200.2 89.5 968.3 1165.9 124.1 3.9 19.7 22.1 67.0 0.6 1.6 4.1 20.6 285.3 97.7 11.7 85.4 214.6 GLTPD2 ENSG00000182327 "Glycolipid transfer protein domain containing 2" A6NH11 17 4788964-4790589 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 73.8" "Group enriched" "Detected in some" 5 "Hepatocytes: 83.7;Proximal tubular cells: 135.8" "Cancer enriched" "Detected in many" 5 "liver cancer: 25.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BEWO: 3.4;CACO-2: 9.2;Hep G2: 13.7;MCF7: 4.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA058295, HPA065267" Uncertain Approved Vesicles "Secreted - unknown location" NA NA 150000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA058295: AB_2683671, HPA065267: AB_2685451" "unprognostic (4.00e-1)" "unprognostic (1.93e-1)" "unprognostic (1.95e-3)" "unprognostic (1.70e-1)" "unprognostic (3.03e-2)" "unprognostic (1.79e-4)" "unprognostic (1.40e-1)" "unprognostic (1.45e-2)" "unprognostic (4.16e-3)" "unprognostic (2.33e-2)" "unprognostic (5.62e-4)" "unprognostic (7.80e-2)" "unprognostic (2.62e-1)" "unprognostic (4.25e-1)" "unprognostic (4.79e-1)" "unprognostic (1.71e-4)" "unprognostic (7.59e-3)" 0.5 0.5 1.3 0.5 1.1 1.5 0.3 2.3 2.7 0.4 0.0 0.5 10.1 0.5 0.0 0.8 0.4 0.3 0.2 1.0 2.1 12.0 73.8 0.4 0.1 3.1 2.8 0.3 0.7 0.2 0.8 0.1 2.0 0.4 0.0 0.3 1.0 0.0 1.3 1.7 6.2 0.0 0.4 1.1 1.1 0.1 1.5 0.0 0.2 0.0 0.0 0.5 0.5 1.4 0.5 1.8 0.1 1.5 0.0 0.0 3.4 0.4 0.0 0.0 0.0 9.2 0.6 0.8 0.9 0.0 0.3 1.7 0.0 0.0 0.0 1.7 1.2 0.1 0.7 13.7 0.1 0.2 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.5 0.4 0.0 4.1 0.1 0.1 0.2 0.6 0.7 0.7 0.5 0.2 0.0 0.7 1.1 0.7 1.6 0.3 0.4 0.0 1.0 0.1 1.7 0.5 0.7 0.4 0.3 0.1 0.5 0.1 0.2 0.5 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.3 1.1 2.3 2.7 1.0 2.1 3.1 2.8 2.0 0.4 1.5 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.1 0.3 0.2 1.5 0.5 0.0 0.0 0.0 0.1 0.4 17.6 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.6 0.2 0.0 0.2 0.0 0.0 2.2 83.7 0.1 0.0 0.2 0.6 0.0 1.3 0.4 0.2 0.6 1.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 1.2 0.0 0.6 0.3 21.1 135.8 0.3 0.0 0.0 0.0 0.0 0.6 0.9 0.0 0.1 0.3 0.3 0.1 0.3 0.4 GLYAT "ACGNAT, GAT" ENSG00000149124 Glycine-N-acyltransferase Q6IB77 11 58640426-58731974 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Detoxification "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "kidney: 571.8;liver: 698.0" "Group enriched" "Detected in some" 6 "Hepatocytes: 346.7;Proximal tubular cells: 1261.0" "Group enriched" "Detected in some" 158 "liver cancer: 21.7;renal cancer: 25.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-937: 1.4" "Not detected" "Not detected" "HPA040251, HPA044094" Enhanced NA NA 21000 "Cluster 81: Kidney & Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA040251: AB_2676902, HPA044094: AB_2678807" "unprognostic (2.15e-2)" "unprognostic (9.38e-4)" "unprognostic (4.60e-2)" "unprognostic (1.65e-3)" "unprognostic (1.83e-1)" "unprognostic (1.60e-1)" "prognostic favorable (1.31e-6)" "unprognostic (2.69e-1)" 47.0 0.1 0.0 0.1 0.1 0.1 8.5 0.1 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.1 0.0 571.8 698.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 1.2 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.3 0.5 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.3 0.3 0.1 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 11.5 0.0 31.3 0.0 0.1 0.0 0.0 123.3 0.0 6.0 0.0 0.0 0.6 0.0 8.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 346.7 0.0 0.0 0.2 0.0 0.0 10.7 0.0 8.2 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1261.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 3.8 0.0 0.0 0.0 GLYATL1 "FLJ34646, MGC15397" ENSG00000166840 "Glycine-N-acyltransferase like 1" Q969I3 11 58905398-59043527 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 576.3" "Group enriched" "Detected in some" 4 "Hepatocytes: 234.3;Proximal tubular cells: 797.1" "Group enriched" "Detected in some" 8 "liver cancer: 14.1;prostate cancer: 13.3;renal cancer: 10.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 2.0;Daudi: 4.9;RPTEC TERT1: 1.5;U-2197: 1.2" HPA039501 Supported Uncertain "Golgi apparatus,Cytosol" NA NA "Cluster 85: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" Cytosol "HPA039501: AB_2676545" "unprognostic (9.46e-3)" "unprognostic (5.33e-2)" "unprognostic (3.90e-5)" "unprognostic (3.93e-3)" "unprognostic (3.54e-3)" "unprognostic (2.17e-1)" "prognostic favorable (3.69e-4)" "unprognostic (3.62e-1)" "unprognostic (2.51e-1)" "unprognostic (1.05e-1)" "unprognostic (2.08e-1)" "unprognostic (2.92e-1)" "prognostic favorable (3.03e-5)" "unprognostic (1.50e-1)" "unprognostic (1.01e-1)" "unprognostic (1.86e-2)" "unprognostic (4.55e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 1.3 0.3 0.4 0.1 0.4 0.3 1.6 0.1 0.7 0.1 1.3 0.9 0.0 0.1 0.3 141.4 576.3 0.0 0.1 0.9 0.2 0.0 1.7 2.6 0.0 0.0 1.1 11.1 0.3 0.2 1.9 0.0 0.0 0.6 0.2 0.0 0.3 0.1 2.7 0.1 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.2 0.1 0.5 0.4 2.0 0.0 4.9 0.0 0.3 0.4 0.0 0.0 0.0 0.8 0.0 0.2 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.5 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.6 0.0 1.2 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.4 0.1 0.3 0.9 0.2 1.1 0.3 0.3 0.3 0.0 0.0 0.0 0.0 3.5 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.3 12.8 0.0 14.7 0.0 0.0 0.0 0.1 107.6 0.1 0.0 2.5 0.1 0.5 0.0 8.0 0.7 0.6 0.0 0.1 0.0 0.1 0.0 0.1 5.0 234.3 0.0 0.0 0.8 0.1 0.0 8.1 0.0 0.0 0.0 3.1 1.8 0.0 0.0 0.0 0.0 0.5 0.2 0.3 0.0 0.0 0.0 1.3 0.0 797.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 1.9 0.1 0.9 0.2 GP2 ZAP75 ENSG00000169347 "Glycoprotein 2" P55259 16 20309574-20327808 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 966 "pancreas: 35381.6" "Cell type enriched" "Detected in some" 5 "Exocrine glandular cells: 504.1" "Cancer enriched" "Detected in many" 14 "pancreatic cancer: 320.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015739, HPA016668" Enhanced "Secreted to digestive system" NA NA 41000 "Cluster 11: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 1: Pancreatic cells - Digestion" "HPA015739: AB_1849905, HPA016668: AB_1849907" "unprognostic (2.14e-2)" "unprognostic (1.97e-2)" "unprognostic (5.68e-2)" "unprognostic (4.29e-2)" "unprognostic (1.63e-1)" "unprognostic (2.84e-1)" "unprognostic (6.35e-2)" "unprognostic (8.17e-3)" "unprognostic (1.27e-1)" "unprognostic (2.36e-1)" 7.1 1.9 0.2 0.9 0.2 0.7 3.8 0.6 0.4 2.5 0.4 3.9 36.6 2.1 0.2 3.9 1.4 18.7 6.5 0.3 0.2 33.4 5.0 1.5 2.1 0.2 0.6 15.4 35381.6 0.0 2.9 2.4 0.3 33.4 6.2 0.1 7.5 0.0 1.6 1.8 10.1 0.1 0.1 2.5 27.4 1.9 0.2 0.1 1.3 0.0 0.2 1.0 1.6 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.3 0.1 0.0 0.2 0.0 0.0 0.2 0.2 0.6 0.4 0.3 0.2 0.2 0.6 0.3 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.7 0.0 0.0 0.2 1.1 0.1 0.1 87.2 0.0 0.0 0.0 0.0 0.0 1.7 9.8 1.3 7.5 0.3 0.5 0.2 0.0 0.0 0.0 504.1 0.0 0.2 0.0 2.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.1 0.0 0.0 0.3 15.6 0.3 0.4 0.0 0.0 4.2 0.2 0.0 0.0 0.0 20.7 13.9 0.4 0.0 69.7 2.0 0.0 0.0 0.3 0.0 0.5 0.2 0.4 0.1 0.0 0.0 0.0 0.1 0.1 19.9 2.1 GPD1 ENSG00000167588 "Glycerol-3-phosphate dehydrogenase 1" P21695 12 50103982-50111313 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 609.9;skeletal muscle: 577.1" "Group enriched" "Detected in many" 4 "Hepatocytes: 99.1;Proximal enterocytes: 247.0;Proximal tubular cells: 298.4" "Cancer enhanced" "Detected in many" "liver cancer: 18.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "ASC diff: 134.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044620, HPA058621" Enhanced NA NA 4700000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA044620: AB_10796803, HPA058621: " "unprognostic (2.65e-2)" "unprognostic (5.60e-2)" "unprognostic (3.28e-2)" "unprognostic (3.37e-2)" "unprognostic (3.26e-1)" "unprognostic (2.54e-1)" "unprognostic (1.45e-3)" "unprognostic (7.19e-2)" "unprognostic (9.42e-2)" "unprognostic (1.58e-1)" "unprognostic (2.24e-2)" "unprognostic (3.24e-1)" "unprognostic (1.37e-1)" "unprognostic (9.58e-2)" "unprognostic (3.37e-1)" "unprognostic (1.14e-1)" "unprognostic (1.12e-2)" 609.9 4.7 9.1 1.6 16.8 0.2 229.2 22.7 12.8 0.3 5.5 6.4 76.4 0.2 5.3 4.9 0.5 16.6 9.2 10.1 14.2 149.3 147.6 18.4 1.0 32.6 18.3 0.3 7.2 13.0 1.3 0.0 26.5 1.3 3.3 1.0 33.0 1.3 577.1 10.2 76.9 1.3 32.7 0.4 3.3 0.8 18.4 1.5 2.7 215.7 0.4 4.1 1.0 49.4 0.1 0.2 0.1 0.1 134.0 0.0 0.3 0.1 0.0 0.0 0.0 27.0 0.1 0.4 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.6 0.1 0.6 25.2 0.0 0.2 0.0 0.3 0.2 0.1 0.3 0.1 0.0 0.7 0.7 0.3 0.0 0.2 0.1 0.4 0.1 3.7 0.0 0.2 0.2 30.2 0.2 0.0 0.6 0.2 0.0 1.5 1.0 0.0 1.8 0.0 0.0 0.0 0.3 0.2 0.1 0.6 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 16.8 22.7 12.8 10.1 14.2 32.6 18.3 26.5 32.7 18.4 49.4 3.4 3.2 3.2 0.0 2.4 0.0 0.2 0.3 0.6 3.2 3.4 3.7 5.8 11.5 1.8 5.5 8.4 0.0 0.0 3.0 43.0 0.9 0.1 0.5 0.1 0.2 1.2 5.3 0.2 0.7 0.0 0.8 4.1 0.2 0.0 0.1 1.1 99.1 2.3 3.3 0.2 9.7 0.0 1.0 0.4 0.0 0.0 5.2 1.8 0.0 1.0 2.8 0.0 0.0 4.0 0.6 8.0 0.0 0.0 0.1 247.0 298.4 0.4 1.7 0.0 7.0 1.1 0.0 0.0 0.8 0.4 0.0 1.2 0.0 10.6 0.2 GPHA2 "A2, GPA2, MGC126572, ZSIG51" ENSG00000149735 "Glycoprotein hormone subunit alpha 2" Q96T91 11 64934471-64935893 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "pancreas: 360.5" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 2.5;Exocrine glandular cells: 17.4;Pancreatic endocrine cells: 2.4;Spermatocytes: 7.7;Spermatogonia: 3.2" "Cancer enriched" "Detected in some" 7 "testis cancer: 15.8" "Region enhanced" "Detected in single" "cerebellum: 3.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "Hep G2: 21.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA067068 Approved Vesicles "Secreted to blood" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 1: Pancreatic cells - Digestion" Vesicles "HPA067068: " "unprognostic (1.13e-1)" "unprognostic (8.31e-3)" "unprognostic (1.51e-2)" "unprognostic (9.22e-4)" "unprognostic (7.88e-3)" "unprognostic (2.62e-1)" "unprognostic (1.45e-1)" "unprognostic (3.20e-2)" "unprognostic (1.82e-1)" "unprognostic (1.75e-1)" "unprognostic (5.03e-2)" "unprognostic (9.86e-3)" "unprognostic (1.70e-1)" 0.0 0.1 0.3 0.2 0.6 0.1 0.1 3.6 0.6 0.1 0.0 0.1 0.1 0.2 0.2 0.0 0.4 16.9 0.0 0.3 0.3 0.8 0.7 0.3 0.6 0.4 0.3 2.7 360.5 0.0 28.0 0.0 0.6 0.7 0.0 0.1 0.3 0.5 0.0 0.5 0.5 0.0 0.2 0.6 1.1 10.8 0.4 0.1 0.3 0.0 0.5 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 21.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 3.6 0.6 0.3 0.3 0.4 0.3 0.6 0.2 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.1 2.5 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 17.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.4 0.0 0.5 0.2 0.0 0.0 0.0 0.0 7.7 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 GPT2 ALT2 ENSG00000166123 "Glutamic--pyruvic transaminase 2" Q8TD30 16 46884362-46931289 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 267.4;skeletal muscle: 176.4;tongue: 184.5" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 64.3;Hepatocytes: 123.9;Syncytiotrophoblasts: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.3;naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Hep G2: 159.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051514 Approved Approved Mitochondria No No "Cluster 19: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA051514: AB_2681516" "unprognostic (1.65e-2)" "unprognostic (3.32e-2)" "unprognostic (2.87e-1)" "unprognostic (3.87e-2)" "unprognostic (3.41e-1)" "unprognostic (1.27e-1)" "unprognostic (1.95e-3)" "unprognostic (3.44e-2)" "unprognostic (6.12e-2)" "prognostic favorable (3.17e-4)" "unprognostic (1.90e-1)" "unprognostic (1.30e-1)" "unprognostic (1.56e-1)" "unprognostic (1.44e-2)" "unprognostic (4.86e-1)" "unprognostic (3.54e-3)" "unprognostic (3.18e-1)" 56.8 10.4 51.6 4.0 49.9 3.8 17.0 49.1 56.9 5.2 38.4 7.7 1.7 3.7 31.4 77.8 7.6 9.8 7.9 51.3 45.7 23.5 103.7 2.1 4.3 69.8 45.9 2.3 267.4 8.3 13.0 3.1 63.9 24.2 4.9 6.9 48.8 10.9 176.4 37.8 3.9 3.1 60.2 2.3 58.6 15.0 54.9 7.7 7.6 184.5 13.4 2.7 7.7 64.5 42.6 19.0 23.8 90.6 32.7 7.0 43.1 28.9 10.9 30.7 19.2 65.3 17.6 29.9 24.7 20.7 15.6 33.6 43.3 42.8 20.4 14.0 21.1 10.5 10.8 159.9 22.4 75.6 9.5 15.2 37.0 30.0 46.3 20.3 15.1 56.1 8.7 23.3 10.3 75.8 15.1 62.9 25.3 52.2 54.2 0.3 26.3 71.1 12.4 21.0 73.7 37.7 14.9 76.4 39.0 9.4 19.6 67.6 11.3 21.1 40.9 14.2 23.4 110.2 36.9 87.1 32.6 48.3 11.7 0.4 0.2 0.0 0.1 0.0 0.0 1.3 0.0 0.1 0.4 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 51.6 49.9 49.1 56.9 51.3 45.7 69.8 45.9 63.9 60.2 54.9 64.5 1.3 6.4 3.4 54.9 4.8 15.9 4.9 6.8 64.3 14.5 6.7 8.4 14.9 8.6 9.1 18.4 22.9 9.2 0.3 10.2 11.7 7.0 9.6 12.2 7.2 2.3 13.1 5.2 16.7 30.2 44.8 7.5 37.2 37.5 3.8 14.9 5.0 123.9 3.8 6.7 18.8 13.4 6.1 3.2 7.3 22.9 4.7 2.3 8.8 1.0 1.1 42.5 1.0 13.6 26.0 25.6 5.2 15.4 7.9 12.4 2.0 38.6 5.4 5.9 0.0 5.2 3.6 2.5 17.3 53.1 16.3 83.3 1.4 2.6 6.3 4.2 GPX3 ENSG00000211445 "Glutathione peroxidase 3" P22352 5 151020438-151028992 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 11673.5" "Cell type enriched" "Detected in many" 4 "Proximal tubular cells: 20125.9" "Cancer enhanced" "Detected in all" "renal cancer: 605.6;thyroid cancer: 856.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 20.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 20.7" "Cell line enriched" "Detected in many" 12 "ASC diff: 7677.4" "Region enhanced" "Detected in all" "hypothalamus: 239.5" "Low region specificity" "Detected in all" CAB069456 Approved "Secreted to blood" NA NA 5090000000 6200000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB069456: AB_1616682" "unprognostic (4.03e-1)" "unprognostic (7.35e-2)" "unprognostic (5.05e-3)" "unprognostic (9.01e-2)" "unprognostic (1.41e-2)" "unprognostic (8.13e-2)" "unprognostic (1.39e-2)" "unprognostic (1.62e-1)" "unprognostic (5.75e-3)" "unprognostic (2.70e-3)" "unprognostic (8.17e-3)" "unprognostic (1.14e-2)" "unprognostic (2.95e-1)" "prognostic unfavorable (1.65e-4)" "unprognostic (2.14e-1)" "unprognostic (5.11e-2)" "unprognostic (1.26e-1)" 4524.7 443.8 57.8 75.4 68.3 7.9 3188.6 62.7 73.8 917.6 578.2 741.2 88.3 416.0 90.7 568.6 1038.4 136.4 2362.4 68.2 117.5 11673.5 986.3 2471.8 133.2 317.7 104.5 517.8 257.0 112.4 793.7 592.2 136.6 557.5 93.4 4204.9 481.4 140.0 847.9 669.7 720.6 61.0 67.5 555.7 641.1 80.4 135.8 26.8 3627.5 458.9 44.9 1196.7 891.7 70.3 2.2 10.0 8.5 2.7 7677.4 6.7 9.2 3.5 0.8 7.9 2.4 177.5 3.9 1.1 214.1 5.6 3.2 2.8 39.6 433.2 6.0 6.1 2.5 1.9 4.3 195.0 294.7 0.5 4.3 649.1 41.2 0.2 1.0 10.6 11.3 1.2 1.2 0.3 11.0 31.4 0.5 1.2 13.8 0.8 0.2 1.0 5.2 1.7 74.1 4.3 11.3 11.4 1.2 31.6 1.9 33.6 43.5 2.1 2.5 2.3 19.6 3.7 1.0 2.7 15.6 2.5 7.0 3.0 0.6 0.0 4.3 0.1 0.0 1.6 0.3 0.0 0.0 0.0 4.2 0.0 0.0 0.0 20.7 0.0 0.2 0.0 0.0 1.6 57.8 68.3 62.7 73.8 68.2 117.5 317.7 104.5 136.6 67.5 135.8 70.3 353.6 9.6 33.7 1.0 106.8 18.5 86.9 94.8 1.2 26.3 31.7 5.5 639.8 18.6 58.3 649.2 43.8 713.8 2.2 2.3 1772.6 5.5 2.9 48.1 71.1 144.6 45.6 24.0 4.0 48.2 1191.3 514.0 50.0 627.9 11.4 274.9 735.3 228.4 151.5 16.8 0.4 5.9 91.6 47.9 86.7 17.5 446.7 160.2 23.2 3.7 0.7 5019.8 0.0 0.0 0.3 9.9 13.8 41.0 2.2 141.8 0.5 20125.9 39.1 86.8 683.7 131.6 264.6 7.1 10.3 13.9 21.6 1767.7 68.3 1.0 1.3 34.3 GRAMD1B "KIAA1201, LINC01059" ENSG00000023171 "GRAM domain containing 1B" Q3KR37 11 123358428-123627774 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 258.8;choroid plexus: 91.8;retina: 96.7" "Cell type enhanced" "Detected in many" "Astrocytes: 94.7;Cone photoreceptor cells: 114.7;Excitatory neurons: 120.7;Inhibitory neurons: 102.8;Oligodendrocyte precursor cells: 95.0;Rod photoreceptor cells: 92.3;Theca cells: 109.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 7.0" "Lineage enriched" "Detected in many" 4 "dendritic cells: 7.0" "Group enriched" "Detected in many" 4 "A549: 62.4;HDLM-2: 168.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008557, HPA075204" Approved Supported "Endoplasmic reticulum,Vesicles,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 58: Brain - Synaptic function" "Cluster 44: HDLM-2 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum, Plasma membrane" Vesicles "HPA008557: AB_1079197, HPA075204: " "unprognostic (1.86e-1)" "unprognostic (7.18e-3)" "unprognostic (2.43e-2)" "unprognostic (2.74e-3)" "unprognostic (8.15e-2)" "unprognostic (4.28e-2)" "unprognostic (2.69e-3)" "unprognostic (4.12e-3)" "unprognostic (1.40e-1)" "unprognostic (2.90e-2)" "unprognostic (9.60e-2)" "unprognostic (8.06e-2)" "prognostic unfavorable (4.30e-7)" "unprognostic (1.39e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (1.69e-1)" 1.8 258.8 22.5 4.3 27.4 18.6 1.1 80.1 52.3 0.9 91.8 1.6 34.6 1.1 9.4 0.6 3.6 12.1 15.0 55.6 19.4 15.5 1.5 2.6 5.4 25.7 20.1 15.2 2.4 0.7 16.6 5.0 24.2 1.1 1.1 96.7 1.9 2.0 3.4 0.5 25.2 1.2 9.4 3.6 11.4 16.8 33.5 6.6 4.9 2.2 3.5 1.2 0.8 26.1 0.1 62.4 3.5 0.1 0.3 0.7 9.5 20.5 14.6 4.1 1.8 2.6 0.4 3.8 10.4 10.1 6.8 0.0 6.2 0.0 4.3 168.5 5.0 0.0 28.3 0.7 0.0 22.1 0.0 1.0 0.1 7.1 0.0 5.2 1.8 1.6 0.0 0.2 3.7 0.5 3.8 7.2 7.6 28.3 23.0 10.8 9.8 6.8 0.2 0.0 20.0 16.3 4.9 0.5 0.1 8.1 0.5 12.0 12.3 23.8 3.2 4.2 1.0 0.0 0.0 0.0 4.6 20.5 1.1 0.0 1.2 0.4 0.4 0.7 0.2 0.0 1.5 1.2 1.7 0.0 0.2 0.2 0.1 1.6 0.7 7.0 0.7 0.5 22.5 27.4 80.1 52.3 55.6 19.4 25.7 20.1 24.2 9.4 33.5 26.1 1.4 0.0 0.5 94.7 0.6 0.0 0.0 0.1 1.2 44.3 1.1 1.0 5.7 21.5 0.2 5.5 114.7 6.9 17.9 0.1 3.9 0.7 9.6 1.6 0.6 1.0 0.0 0.0 120.7 0.4 3.7 1.6 16.3 0.9 0.0 41.9 0.7 0.0 2.6 45.4 102.8 1.8 0.0 3.8 2.6 2.7 0.6 7.5 0.0 37.5 2.5 23.4 0.0 95.0 5.5 3.9 1.3 0.7 2.4 0.1 17.3 8.9 0.4 92.3 0.0 3.0 4.2 3.9 1.9 0.1 0.4 2.5 7.2 109.3 1.5 0.0 GREB1 KIAA0575 ENSG00000196208 "Growth regulating estrogen receptor binding 1" Q4ZG55 2 11482341-11642788 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "ovary: 278.3" "Cell type enriched" "Detected in many" 9 "Granulosa cells: 545.2" "Cancer enhanced" "Detected in many" "prostate cancer: 17.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 40.3;Hep G2: 39.6;MCF7: 61.8;SH-SY5Y: 40.5;SK-MEL-30: 30.4;T-47d: 138.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA024616, HPA027843, HPA028416" Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" "Mitochondria, Cytosol" "HPA024616: AB_10599728, HPA027843: AB_10601103, HPA028416: AB_10601344" "unprognostic (1.52e-2)" "unprognostic (4.63e-1)" "unprognostic (1.46e-1)" "prognostic favorable (1.05e-4)" "unprognostic (1.23e-2)" "unprognostic (1.32e-1)" "unprognostic (6.29e-2)" "unprognostic (1.24e-1)" "unprognostic (6.19e-2)" "unprognostic (1.38e-1)" "unprognostic (3.68e-1)" "unprognostic (3.63e-2)" "unprognostic (7.51e-4)" "unprognostic (2.42e-2)" "unprognostic (3.34e-1)" "unprognostic (2.46e-3)" "unprognostic (4.80e-2)" 1.8 3.4 8.5 0.7 9.6 0.4 13.7 2.1 9.9 60.2 0.8 1.0 0.7 61.3 7.0 0.6 53.4 2.8 4.6 7.8 20.4 1.8 3.1 1.4 0.6 8.7 8.5 278.3 7.6 0.7 8.9 3.0 4.4 63.4 0.2 1.5 1.1 3.8 4.0 2.7 0.9 12.8 3.2 0.2 3.0 14.9 10.7 0.3 0.6 4.8 0.3 1.7 21.5 6.5 0.1 1.0 40.3 0.5 0.2 0.2 1.8 0.0 0.1 0.1 0.3 0.3 0.2 2.5 0.3 0.0 6.9 0.2 3.1 0.2 0.1 5.1 3.6 0.4 0.3 39.6 0.5 0.3 2.1 0.5 2.2 0.6 0.4 0.4 0.0 3.9 0.5 1.0 0.3 61.8 1.2 2.0 13.0 0.1 0.1 29.1 0.0 1.9 0.1 0.0 11.8 40.5 0.9 1.1 30.4 5.2 138.0 0.7 0.0 4.1 2.0 0.4 0.1 6.0 4.4 24.7 6.8 11.9 1.2 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.1 0.1 0.1 0.1 0.0 8.5 9.6 2.1 9.9 7.8 20.4 8.7 8.5 4.4 3.2 10.7 6.5 0.4 0.0 0.5 20.2 0.7 0.8 1.9 0.0 0.6 4.8 24.7 13.7 8.3 5.7 0.6 0.0 2.1 0.2 0.1 0.1 0.0 0.3 0.8 35.7 36.0 1.3 0.0 0.0 15.0 0.2 3.6 16.9 0.0 23.4 3.8 545.2 0.7 8.9 3.2 3.3 46.9 0.0 0.0 0.0 1.2 2.5 20.2 1.4 5.4 1.0 0.0 0.2 0.0 11.6 20.9 0.4 0.0 55.3 5.0 14.3 0.0 2.5 2.9 0.5 0.0 7.2 14.8 1.1 2.9 0.3 0.3 0.3 1.1 33.1 0.0 2.5 GRIK2 "GluK2, GLUR6, MRT6" ENSG00000164418 "Glutamate ionotropic receptor kainate type subunit 2" Q13002 6 101181257-102070083 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "brain: 93.3" "Group enriched" "Detected in some" 26 "Excitatory neurons: 724.6;Inhibitory neurons: 2376.0;Oligodendrocyte precursor cells: 1234.0" "Cancer enriched" "Detected in some" 5 "glioma: 3.9" "Region enhanced" "Detected in all" "cerebellum: 93.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 16.4;BJ hTERT+: 26.6;fHDF/TERT166: 20.8;HAP1: 10.2;SiHa: 11.1;WM-115: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014395, HPA014623, CAB022463" Approved "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB022463: , HPA014395: AB_1850303, HPA014623: AB_1850305" "unprognostic (1.43e-3)" "unprognostic (1.26e-2)" "unprognostic (3.99e-2)" "unprognostic (3.20e-1)" "unprognostic (1.92e-1)" "unprognostic (3.48e-2)" "unprognostic (2.57e-1)" "unprognostic (4.32e-2)" "unprognostic (8.46e-2)" "unprognostic (9.19e-2)" "unprognostic (4.01e-2)" "unprognostic (1.36e-1)" "unprognostic (1.34e-5)" "unprognostic (1.94e-3)" "unprognostic (7.78e-2)" "unprognostic (1.09e-2)" "unprognostic (8.68e-4)" 0.2 1.8 18.7 0.4 20.3 0.3 0.2 93.3 25.2 1.4 0.0 0.5 0.6 0.4 1.1 0.4 0.3 0.5 4.5 20.7 28.4 0.8 0.1 0.1 0.1 1.0 6.8 0.4 2.6 0.0 1.6 2.4 7.9 0.9 0.4 4.2 0.7 1.2 0.9 1.6 0.6 0.3 1.6 0.4 0.3 0.7 19.8 0.0 3.4 0.1 0.0 0.5 0.4 7.6 0.1 0.1 3.1 0.2 3.6 0.1 0.0 16.4 26.6 0.8 0.5 0.0 0.3 0.1 0.0 20.8 0.0 5.1 10.2 0.0 0.3 0.0 0.0 1.7 8.5 0.0 0.9 0.0 0.2 0.3 0.0 0.0 1.0 2.3 0.0 0.0 0.0 0.4 6.2 0.0 0.0 0.2 2.7 0.0 0.2 0.1 0.4 0.1 0.7 0.0 3.3 7.0 11.1 0.0 0.5 0.5 0.0 0.8 0.0 2.1 0.5 0.1 1.3 0.1 0.0 0.1 1.5 0.0 24.6 0.5 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.0 0.0 18.7 20.3 93.3 25.2 20.7 28.4 1.0 6.8 7.9 1.6 19.8 7.6 0.2 0.0 0.5 54.9 0.0 0.6 1.0 0.1 0.6 11.4 0.1 0.0 5.9 0.0 1.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 3.8 3.4 1.9 0.4 1.8 0.0 724.6 0.6 0.0 1.8 0.0 0.5 0.0 13.0 0.0 0.0 0.1 0.0 2376.0 0.0 0.0 0.0 0.0 7.7 0.3 0.1 1.8 38.4 0.0 0.5 0.0 1234.0 40.5 0.1 1.1 0.4 0.0 0.8 0.1 0.0 2.2 1.1 0.0 0.7 4.6 0.0 0.5 0.1 0.6 0.0 0.0 4.3 0.1 0.9 GRM1 "GPRC1A, mGlu1, MGLUR1, PPP1R85" ENSG00000152822 "Glutamate metabotropic receptor 1" Q13255 6 146027646-146437601 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 27.6" "Group enriched" "Detected in some" 6 "Excitatory neurons: 215.5;Inhibitory neurons: 138.8;Rod photoreceptor cells: 124.9" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 27.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA015701 Approved Supported Approved Vesicles NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA015701: AB_1853917" "unprognostic (1.04e-2)" "unprognostic (7.33e-2)" "unprognostic (3.73e-3)" "unprognostic (9.77e-3)" "unprognostic (6.75e-2)" "unprognostic (2.13e-1)" "unprognostic (1.09e-1)" "unprognostic (5.78e-2)" "unprognostic (4.31e-2)" "unprognostic (2.93e-2)" "unprognostic (9.48e-3)" "unprognostic (7.92e-2)" "unprognostic (1.84e-2)" "unprognostic (1.03e-1)" "unprognostic (3.50e-2)" "unprognostic (8.33e-3)" "unprognostic (9.76e-2)" 0.0 0.0 3.3 0.0 3.6 0.0 0.0 27.6 6.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.8 7.3 2.3 0.7 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 5.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 7.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 3.6 27.6 6.8 7.3 2.3 0.0 3.1 0.9 0.0 7.7 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 13.8 0.0 0.0 3.7 0.0 0.0 1.8 16.7 0.0 0.0 0.0 1.9 0.0 8.5 0.1 0.0 0.2 0.0 0.0 215.5 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.6 6.7 138.8 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 3.7 0.0 4.0 0.0 8.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 124.9 0.0 0.0 0.1 1.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GSTA1 ENSG00000243955 "Glutathione S-transferase alpha 1" P08263 6 52791371-52803860 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Oxidoreductase, Peroxidase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 916.5;kidney: 943.1;liver: 2610.5" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 1652.6;Granulosa cells: 3177.1;Proximal enterocytes: 4294.8;Proximal tubular cells: 3190.6;Theca cells: 4578.2" "Cancer enriched" "Detected in many" 4 "liver cancer: 555.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 14 "Hep G2: 263.9" "HPA004342, HPA048934, HPA053817" Supported Supported Cytosol NA NA 27800000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA004342: AB_1078987, HPA048934: AB_2680563, HPA053817: AB_2630367" "unprognostic (4.84e-3)" "unprognostic (2.40e-2)" "unprognostic (3.40e-1)" "unprognostic (4.78e-2)" "unprognostic (1.72e-1)" "unprognostic (1.26e-1)" "unprognostic (1.00e-2)" "prognostic favorable (8.66e-4)" "unprognostic (5.75e-2)" "unprognostic (6.90e-3)" "unprognostic (3.00e-1)" "unprognostic (8.27e-2)" "prognostic unfavorable (3.71e-4)" "unprognostic (1.21e-1)" "unprognostic (4.26e-3)" "unprognostic (1.02e-1)" "unprognostic (2.16e-2)" 0.5 916.5 0.0 2.5 0.0 0.0 4.2 0.0 0.2 2.0 0.0 7.3 672.0 0.4 7.0 5.3 86.1 119.5 0.2 0.0 0.0 943.1 2610.5 12.2 0.5 0.0 0.0 78.9 148.6 0.0 0.2 0.5 0.0 18.7 8.1 0.0 21.5 0.6 0.1 1.2 674.6 0.3 0.0 0.2 135.5 336.8 0.3 0.1 0.1 0.0 11.5 2.2 5.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 19.4 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.5 0.1 263.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.4 2.1 0.0 0.2 1.5 2.1 0.3 0.0 0.0 1.1 0.0 0.2 0.5 0.5 0.1 0.6 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 6.4 7.7 0.0 13.5 0.0 5.0 35.7 0.0 0.0 7.0 1.5 0.0 453.2 159.9 73.5 0.0 0.1 0.1 5.8 536.1 71.3 11.8 0.4 0.1 3.1 3.0 45.5 0.0 1652.6 0.2 7.3 116.7 0.5 2.5 3177.1 26.4 1013.9 0.1 0.0 0.0 165.6 42.7 31.5 0.0 43.0 65.6 25.3 0.0 0.0 13.3 0.0 1.0 0.0 0.1 629.1 187.4 4.5 0.2 27.6 4294.8 3190.6 533.5 0.0 0.0 0.0 98.6 36.8 3.4 6.8 0.0 0.5 10.4 4578.2 295.3 58.7 GSTA2 GST2 ENSG00000244067 "Glutathione S-transferase alpha 2" P09210 6 52750087-52763475 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 696.0;liver: 2058.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 201.6;Distal tubular cells: 213.2;Exocrine glandular cells: 239.6;Pancreatic endocrine cells: 334.7;Proximal enterocytes: 367.0;Proximal tubular cells: 1186.6;Respiratory ciliated cells: 435.5" "Group enriched" "Detected in many" 16 "liver cancer: 124.6;renal cancer: 48.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "CACO-2: 25.9;Hep G2: 20.0" "HPA004342, HPA048934, HPA053817" Supported Supported Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA004342: AB_1078987, HPA048934: AB_2680563, HPA053817: AB_2630367" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (2.72e-2)" "unprognostic (1.15e-1)" "unprognostic (6.43e-3)" "unprognostic (2.41e-1)" "unprognostic (1.30e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (4.34e-2)" "unprognostic (1.91e-1)" "unprognostic (6.54e-2)" 0.4 4.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.6 149.5 0.0 0.7 0.1 2.5 109.4 0.0 0.0 0.0 696.0 2058.5 4.8 0.1 0.0 0.0 0.2 299.2 0.0 0.0 0.1 0.0 3.8 0.1 0.0 0.5 0.0 0.0 0.0 115.5 0.0 0.0 0.0 11.7 44.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 25.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.2 0.0 20.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 1.7 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.6 0.0 0.0 0.3 0.6 0.5 0.5 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 1.7 0.0 0.2 1.5 0.0 0.0 0.1 0.1 0.0 201.6 31.1 16.5 0.0 0.0 0.0 0.1 213.2 8.1 6.9 0.0 0.0 0.6 0.0 0.0 0.0 239.6 0.2 0.5 7.7 0.0 0.0 37.2 0.7 124.2 0.1 0.0 0.0 13.7 2.0 2.2 0.0 14.6 1.2 5.1 0.0 0.0 5.2 0.0 0.0 0.0 0.1 334.7 18.8 0.4 0.0 3.9 367.0 1186.6 435.5 0.0 0.0 0.0 1.5 1.9 0.7 0.0 0.0 0.0 2.6 10.4 30.1 1.3 GSTA5 ENSG00000182793 "Glutathione S-transferase alpha 5" Q7RTV2 6 52831655-52840843 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 10 "Smooth muscle cells: 23.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA004342, HPA048934, HPA053817" Uncertain Approved Cytosol NA NA "Cluster 10: Non-specific - Unknown function" Cytosol "HPA004342: AB_1078987, HPA048934: AB_2680563, HPA053817: AB_2630367" "unprognostic (1.97e-2)" "unprognostic (2.83e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 2.2 0.4 0.0 0.0 0.0 23.6 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 H2AC1 "bA317E16.2, H2AFR, HIST1H2AA" ENSG00000164508 "H2A clustered histone 1" Q96QV6 6 25726063-25726562 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 19 "testis: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041189 Supported Approved Nucleoplasm NA NA "Cluster 83: Testis - Spermatogenesis" Nucleoplasm "HPA041189: AB_2677357" "unprognostic (4.53e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 H2BC1 "bA317E16.3, H2BFU, HIST1H2BA, STBP, TSH2B" ENSG00000146047 "H2B clustered histone 1" Q96A08 6 25726777-25727345 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 18 "testis: 6.4" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "testis cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB011603, HPA042205, HPA043013" Enhanced NA NA "Cluster 78: Testis - Spermatogenesis" "CAB011603: AB_2118143, HPA042205: AB_2677900, HPA043013: AB_2678269" "unprognostic (3.94e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HAO2 "GIG16, HAOX2" ENSG00000116882 "Hydroxyacid oxidase 2" Q9NYQ3 1 119368779-119394130 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "kidney: 303.7;liver: 425.6" "Group enriched" "Detected in some" 7 "Hepatocytes: 256.8;Proximal tubular cells: 450.1" "Group enriched" "Detected in some" 26 "liver cancer: 25.6;renal cancer: 11.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050355 Uncertain Vesicles,Cytosol NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Vesicles "HPA050355: " "unprognostic (1.13e-1)" "unprognostic (1.68e-2)" "unprognostic (2.07e-1)" "unprognostic (1.00e-1)" "unprognostic (6.22e-2)" "unprognostic (5.33e-3)" "unprognostic (2.80e-2)" "unprognostic (3.27e-1)" "unprognostic (3.15e-1)" "unprognostic (3.17e-1)" "unprognostic (1.41e-1)" "unprognostic (1.73e-1)" "prognostic favorable (4.92e-4)" "unprognostic (9.66e-2)" "unprognostic (1.79e-1)" "unprognostic (2.89e-2)" "unprognostic (5.14e-4)" 0.0 0.6 0.2 0.1 0.6 0.0 0.6 0.1 0.6 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 303.7 425.6 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.0 4.4 0.1 0.0 0.1 0.4 0.2 0.1 0.3 23.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.1 0.6 0.2 0.0 0.2 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.7 0.0 11.0 0.0 0.0 0.0 0.0 49.0 0.0 0.0 0.0 0.0 0.6 0.0 13.5 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 4.2 256.8 0.1 0.0 0.1 0.0 0.0 6.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 450.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 HAVCR2 "CD366, FLJ14428, Tim-3, TIM3, TIMD3" ENSG00000135077 "Hepatitis A virus cellular receptor 2" Q8TDQ0 5 157085832-157142869 "CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 32.1" "Cell type enhanced" "Detected in many" "dendritic cells: 87.6;granulocytes: 80.6;Hofbauer cells: 148.3;Kupffer cells: 89.1;Langerhans cells: 67.8;Macrophages: 83.2;monocytes: 49.5;NK-cells: 70.0;Proximal tubular cells: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 53.8;intermediate monocyte: 57.9;myeloid DC: 137.9;NK-cell: 97.1;non-classical monocyte: 36.1" "Group enriched" "Detected in all" 6 "dendritic cells: 137.9;monocytes: 57.9;NK-cells: 97.1" "Cell line enhanced" "Detected in some" "ASC diff: 7.8;Daudi: 6.4;HDLM-2: 26.3;HMC-1: 6.0;RPMI-8226: 21.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB026003 Enhanced NA NA 9900000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB026003: " "unprognostic (2.50e-2)" "unprognostic (1.11e-2)" "unprognostic (5.18e-2)" "unprognostic (2.04e-3)" "unprognostic (3.79e-2)" "unprognostic (1.14e-1)" "unprognostic (6.69e-2)" "unprognostic (2.54e-1)" "unprognostic (9.18e-2)" "unprognostic (1.42e-1)" "unprognostic (8.48e-2)" "unprognostic (5.13e-2)" "unprognostic (7.83e-2)" "unprognostic (1.89e-1)" "unprognostic (1.83e-2)" "unprognostic (2.13e-1)" "unprognostic (1.34e-1)" 14.2 8.2 9.5 19.7 11.1 13.9 5.3 11.1 13.3 4.9 10.4 5.4 4.0 3.2 6.0 3.7 3.3 12.8 2.5 9.1 11.8 26.8 9.8 22.6 32.1 18.0 13.7 1.7 3.0 2.8 1.8 16.9 16.9 2.1 6.8 1.2 2.9 2.9 1.7 2.2 4.9 7.9 16.1 24.1 4.7 2.0 17.5 9.1 1.6 2.1 14.0 13.1 1.2 27.2 0.0 0.2 0.1 0.2 7.8 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.1 6.4 0.3 0.0 0.2 0.1 0.0 0.0 0.0 26.3 0.0 1.1 0.1 0.0 0.0 0.0 6.0 0.4 0.4 0.0 0.2 0.0 0.0 0.7 0.1 2.3 0.0 0.1 0.1 3.9 0.2 0.0 0.0 0.1 3.0 21.5 0.3 0.0 0.2 0.1 0.0 0.1 0.2 0.5 0.2 0.3 0.0 0.9 0.3 0.3 0.0 0.3 1.8 0.2 0.1 0.7 0.1 16.7 53.8 0.1 14.6 57.9 3.0 1.2 5.9 7.9 137.9 0.5 7.0 9.5 2.5 97.1 36.1 16.4 11.5 43.1 9.5 11.1 11.1 13.3 9.1 11.8 18.0 13.7 16.9 16.1 17.5 27.2 1.2 6.4 6.5 2.0 5.9 1.0 0.2 0.1 0.0 0.9 0.7 1.5 1.1 0.0 1.9 0.0 0.0 0.6 87.6 0.3 7.9 0.1 11.1 0.1 0.1 3.7 0.0 1.3 2.1 0.0 0.8 0.9 0.5 0.1 80.6 0.1 1.1 0.5 148.3 0.0 1.7 0.3 0.0 89.1 67.8 7.8 0.3 83.2 3.6 31.9 49.5 0.1 70.0 1.0 4.8 0.1 0.1 0.0 16.3 0.5 0.1 57.7 0.0 0.2 6.6 0.7 0.5 0.3 0.4 0.1 1.3 1.1 26.3 1.5 0.2 0.3 HECW1 "KIAA0322, NEDL1" ENSG00000002746 "HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1" Q76N89 7 43112629-43566001 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 16.4;kidney: 7.8" "Cell type enhanced" "Detected in some" "Early spermatids: 135.6;Excitatory neurons: 533.3;Inhibitory neurons: 157.3;Late spermatids: 72.0;Oligodendrocyte precursor cells: 277.9" "Not detected" "Not detected" "Region enriched" "Detected in many" 4 "cerebral cortex: 16.4" "Group enriched" "Detected in some" 4 "basophil: 4.9;neutrophil: 3.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 4.9" "Cell line enhanced" "Detected in some" "A549: 3.8;GAMG: 3.7;U-266/70: 12.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007203, HPA007593, HPA007609" Uncertain Supported Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA007203: AB_2667776, HPA007593: AB_1852305, HPA007609: AB_2117518" "unprognostic (1.40e-1)" "unprognostic (2.85e-3)" "unprognostic (2.57e-1)" "unprognostic (4.39e-1)" "unprognostic (2.43e-2)" "unprognostic (2.80e-2)" "unprognostic (8.65e-4)" "unprognostic (6.93e-2)" "unprognostic (7.30e-2)" "unprognostic (7.31e-2)" "unprognostic (3.43e-2)" "unprognostic (2.67e-2)" "unprognostic (1.43e-3)" "unprognostic (1.64e-2)" "unprognostic (5.23e-3)" "unprognostic (1.89e-2)" "unprognostic (2.42e-2)" 0.1 0.0 1.5 0.2 1.7 0.5 0.2 0.0 16.4 0.1 0.0 0.2 0.0 0.2 0.6 1.0 0.1 1.9 0.0 0.7 0.0 7.8 0.1 0.1 0.4 0.2 0.0 0.3 0.0 0.2 0.0 0.1 0.1 1.3 0.1 2.2 0.4 0.2 0.9 0.6 0.1 0.1 0.0 0.1 0.3 1.8 0.2 0.0 0.5 2.6 0.2 0.3 0.1 3.8 0.0 3.8 0.3 0.5 0.0 0.0 0.0 1.2 2.2 0.1 0.5 0.0 0.0 0.2 2.3 2.2 3.7 0.2 0.0 0.0 0.2 0.1 0.7 0.0 0.3 0.2 0.2 1.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.3 0.0 0.0 0.0 0.0 1.8 0.1 0.7 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.0 0.0 0.2 0.2 0.0 0.0 0.6 0.8 0.9 0.3 12.0 0.4 0.0 2.7 0.3 0.0 4.9 0.8 0.7 0.3 0.5 0.2 0.6 0.3 0.1 0.1 1.0 0.3 0.3 3.3 0.6 0.6 0.9 0.1 0.0 1.5 1.7 0.0 16.4 0.7 0.0 0.2 0.0 0.1 0.0 0.2 3.8 0.0 0.0 0.0 7.8 0.1 0.4 0.3 0.0 0.0 15.4 0.1 0.3 1.4 0.0 0.0 0.0 4.2 0.0 0.0 0.5 0.0 0.0 135.6 1.1 3.6 0.2 0.0 0.0 533.3 0.0 0.1 0.7 0.0 0.7 0.0 0.0 0.4 0.1 0.0 45.4 157.3 0.1 0.0 0.0 1.4 72.0 0.3 0.2 0.0 24.4 0.1 0.6 0.0 277.9 4.8 0.0 1.4 0.4 0.0 0.4 4.3 15.8 0.0 1.9 0.0 0.6 0.4 3.2 3.3 0.3 0.3 0.0 0.6 0.2 0.5 0.3 HEPACAM2 FLJ38683 ENSG00000188175 "HEPACAM family member 2" A8MVW5 7 93188534-93226469 "Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "intestine: 96.2" "Group enriched" "Detected in some" 11 "Enteroendocrine cells: 218.2;Intestinal goblet cells: 387.5;Ionocytes: 349.9;Paneth cells: 318.1" "Group enriched" "Detected in many" 5 "colorectal cancer: 8.4;pancreatic cancer: 10.7;renal cancer: 10.6;stomach cancer: 5.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 36 "SCLC-21H: 172.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA012381 Supported "Nucleoplasm,Vesicles,Mitotic spindle" Yes NA 210000 "Cluster 9: Intestine - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 27: Mucus-secreting cells - Mucin production" "Vesicles, Mitotic spindle" Nucleoplasm "HPA012381: AB_1853037" "unprognostic (2.01e-3)" "unprognostic (6.05e-2)" "prognostic favorable (9.73e-5)" "unprognostic (1.33e-2)" "unprognostic (7.27e-2)" "unprognostic (2.24e-2)" "unprognostic (4.48e-2)" "unprognostic (8.40e-3)" "unprognostic (7.61e-2)" "unprognostic (8.68e-2)" "unprognostic (5.37e-3)" "unprognostic (4.93e-2)" "unprognostic (3.64e-3)" "unprognostic (2.06e-1)" "unprognostic (4.73e-2)" "unprognostic (3.82e-1)" "unprognostic (6.34e-2)" 0.1 0.1 0.0 2.3 0.0 2.5 8.9 0.0 0.1 0.0 0.0 64.3 30.1 0.0 0.5 0.1 0.0 0.2 0.1 0.0 0.0 15.2 0.0 0.1 0.0 0.1 0.1 0.0 4.3 0.4 7.3 0.2 0.0 0.8 96.2 0.0 2.6 1.4 0.0 0.0 48.0 1.5 0.1 0.1 10.1 3.2 0.0 0.1 0.0 0.0 1.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.5 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 172.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.7 0.4 0.3 1.1 0.7 0.0 0.0 15.1 6.6 0.2 0.0 0.9 5.5 0.0 0.0 0.0 17.2 9.8 0.1 2.5 0.0 0.0 0.1 218.2 18.7 0.5 0.0 0.0 0.1 27.5 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.6 387.5 349.9 0.0 0.0 2.4 0.0 0.0 7.2 1.0 0.0 0.0 0.0 0.0 2.2 0.0 318.1 0.0 0.1 0.9 11.5 0.0 0.3 0.0 0.0 0.0 0.1 5.6 1.2 0.0 0.1 0.1 0.1 0.0 19.7 0.3 HGD "AKU, HGO" ENSG00000113924 "Homogentisate 1,2-dioxygenase" Q93099 3 120628172-120682269 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "kidney: 200.3;liver: 752.6" "Cell type enhanced" "Detected in many" "Distal tubular cells: 103.7;Endometrial ciliated cells: 113.9;Glandular and luminal cells: 127.8;Hepatocytes: 534.7;Proximal tubular cells: 477.5" "Cancer enriched" "Detected in many" 4 "liver cancer: 119.8" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.1" "Cell line enhanced" "Detected in some" "CACO-2: 55.8;EFO-21: 82.7;Hep G2: 186.6;OE19: 328.0;RPTEC TERT1: 212.2" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.2" "HPA047374, HPA052359" Enhanced Approved "Golgi apparatus" NA NA 700000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "HPA047374: AB_2680019, HPA052359: AB_2681798" "unprognostic (1.36e-1)" "unprognostic (9.89e-2)" "unprognostic (3.93e-2)" "prognostic favorable (1.78e-4)" "unprognostic (1.56e-1)" "unprognostic (2.05e-1)" "unprognostic (5.65e-3)" "unprognostic (7.20e-2)" "unprognostic (6.05e-2)" "unprognostic (2.41e-3)" "unprognostic (2.68e-2)" "unprognostic (1.16e-1)" "unprognostic (4.29e-3)" "unprognostic (8.57e-2)" "unprognostic (1.78e-1)" "unprognostic (3.71e-3)" "unprognostic (1.43e-1)" 0.4 0.3 0.4 2.5 1.9 0.5 12.5 0.6 0.8 27.4 1.5 16.7 31.6 3.1 13.0 0.4 4.2 61.7 0.3 0.5 0.4 200.3 752.6 0.8 0.4 0.4 0.4 0.2 31.2 7.0 0.2 0.2 0.4 44.5 20.3 0.7 4.2 4.2 0.1 0.9 25.6 0.5 0.4 0.6 25.5 0.1 0.5 0.7 55.1 0.2 0.1 0.2 0.1 0.6 0.0 12.3 4.6 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 55.8 10.7 0.1 82.7 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.2 186.6 0.0 0.4 1.0 0.0 0.2 0.1 0.0 0.1 0.1 0.4 0.0 0.3 0.5 0.0 0.0 0.2 0.3 328.0 0.0 0.1 0.3 0.1 212.2 0.0 0.2 0.2 0.2 0.9 0.0 0.0 0.2 1.0 0.6 0.1 0.9 0.2 0.1 0.0 0.3 0.5 0.2 0.8 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.3 0.4 1.9 0.6 0.8 0.5 0.4 0.4 0.4 0.4 0.4 0.5 0.6 0.1 0.0 2.0 0.3 5.9 0.0 0.4 0.6 0.0 0.3 7.5 1.7 0.3 81.5 4.9 27.6 2.1 0.0 0.3 18.5 103.7 7.2 0.2 113.9 17.1 1.2 43.8 24.0 3.2 17.8 0.0 0.4 19.4 127.8 1.3 0.0 16.4 534.7 0.2 0.0 0.6 16.0 2.0 16.1 0.0 0.0 0.0 21.3 0.0 1.9 2.0 4.2 0.0 0.0 0.5 12.1 35.6 0.0 0.0 12.9 54.6 477.5 4.1 0.2 0.0 0.2 1.1 0.1 0.0 0.0 0.0 0.0 3.8 0.4 9.1 0.4 HNF1A "HNF1, LFB1, MODY3, TCF1" ENSG00000135100 "HNF1 homeobox A" 12 120978543-121002512 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 15.4;kidney: 16.7;liver: 34.7;pancreas: 9.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 14.5;Hepatocytes: 15.8;Intestinal goblet cells: 9.4;Paneth cells: 14.8;Proximal enterocytes: 33.4;Proximal tubular cells: 16.0;Undifferentiated cells: 10.8" "Group enriched" "Detected in many" 4 "colorectal cancer: 4.5;liver cancer: 3.6;pancreatic cancer: 1.4;renal cancer: 3.6;stomach cancer: 4.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A549: 8.9;CACO-2: 29.4;Hep G2: 32.5;OE19: 15.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB010430, HPA035231" Enhanced Supported Nucleoplasm NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "CAB010430: AB_2116746, HPA035231: AB_2674528" "unprognostic (5.92e-3)" "unprognostic (8.47e-2)" "unprognostic (4.12e-3)" "unprognostic (6.18e-3)" "unprognostic (3.72e-1)" "unprognostic (1.27e-2)" "unprognostic (9.18e-2)" "unprognostic (9.18e-2)" "unprognostic (2.99e-1)" "unprognostic (2.01e-1)" "unprognostic (9.77e-3)" "unprognostic (5.21e-2)" "unprognostic (6.25e-3)" "unprognostic (5.55e-2)" "unprognostic (2.48e-1)" "unprognostic (6.93e-3)" 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.1 0.2 0.0 5.5 15.4 0.2 0.0 0.1 1.1 0.8 0.0 0.1 0.1 16.7 34.7 0.0 0.0 0.1 0.1 0.0 9.5 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.2 14.3 0.1 0.0 0.0 4.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.9 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 29.4 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.5 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.5 0.0 0.0 0.6 0.2 0.0 1.2 4.3 0.0 1.8 0.0 0.1 0.4 14.5 0.0 2.6 0.0 1.3 0.2 0.3 4.8 0.0 0.2 5.3 0.1 0.2 4.6 0.5 0.0 0.1 0.4 15.8 0.1 0.0 0.2 9.4 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.7 0.5 0.0 0.5 0.0 3.9 14.8 0.0 0.1 0.5 33.4 16.0 0.0 0.3 0.0 0.8 0.3 0.1 0.3 0.0 0.3 0.0 0.5 0.0 10.8 0.4 HNF4A "HNF4, MODY, MODY1, NR2A1, TCF14" ENSG00000101076 "Hepatocyte nuclear factor 4 alpha" P41235 20 44355700-44434596 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 102.4;kidney: 43.3;liver: 117.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 232.6;Hepatocytes: 186.8;Intestinal goblet cells: 69.8;Paneth cells: 120.0;Proximal enterocytes: 153.9;Proximal tubular cells: 170.1;Undifferentiated cells: 136.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 48.2;liver cancer: 38.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "CACO-2: 154.4;Hep G2: 114.8;OE19: 42.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004712, CAB019417" Enhanced Supported Nucleoplasm NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB019417: AB_2295208, HPA004712: AB_1079075" "unprognostic (2.47e-1)" "unprognostic (3.08e-1)" "unprognostic (2.34e-1)" "unprognostic (2.29e-1)" "unprognostic (8.54e-2)" "unprognostic (1.56e-2)" "unprognostic (6.90e-2)" "unprognostic (4.79e-3)" "unprognostic (2.59e-2)" "unprognostic (3.77e-2)" "unprognostic (2.45e-2)" "unprognostic (1.05e-1)" "unprognostic (2.75e-2)" "unprognostic (8.40e-3)" "unprognostic (2.12e-1)" "unprognostic (2.70e-2)" 0.2 0.1 0.1 5.9 0.2 0.1 0.1 0.2 0.2 0.0 8.4 58.6 102.4 0.1 0.0 0.1 1.0 5.9 0.0 0.4 0.0 43.3 117.1 0.1 0.1 0.0 0.0 0.0 25.2 0.0 0.0 0.0 0.0 0.0 44.1 0.1 0.0 0.1 0.2 0.0 82.6 1.8 0.0 0.0 22.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 14.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 154.4 6.0 0.1 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 114.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 42.2 0.0 0.0 0.1 0.7 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 1.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 35.8 0.0 12.9 0.0 0.0 0.0 232.6 15.6 7.8 4.0 2.5 0.1 0.4 35.9 2.7 0.5 22.1 0.0 0.1 38.2 0.1 4.5 0.0 3.6 186.8 0.0 0.0 0.3 69.8 0.0 5.3 0.0 18.7 0.3 1.6 0.0 0.0 1.0 0.0 0.0 0.0 0.1 21.0 120.0 0.4 0.1 0.3 153.9 170.1 0.0 0.0 0.0 0.6 0.2 0.4 0.0 0.0 0.0 0.0 0.7 0.8 136.1 0.2 HNF4G NR2A2 ENSG00000164749 "Hepatocyte nuclear factor 4 gamma" Q14541 8 75407914-75566834 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 114.6" "Cell type enhanced" "Detected in many" "Astrocytes: 39.8;Distal enterocytes: 51.0;Intestinal goblet cells: 32.3;Paneth cells: 54.3;Proximal enterocytes: 165.3;Undifferentiated cells: 36.9" "Group enriched" "Detected in many" 5 "colorectal cancer: 8.5;liver cancer: 2.8;pancreatic cancer: 4.0;renal cancer: 4.6;stomach cancer: 10.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.3;CAPAN-2: 16.1;Karpas-707: 4.5;OE19: 10.0;PC-3: 4.8;THP-1: 5.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005438, HPA010610" Enhanced Enhanced "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA005438: AB_1850822, HPA010610: AB_2668318" "unprognostic (2.09e-1)" "unprognostic (2.90e-1)" "unprognostic (1.77e-2)" "unprognostic (9.44e-2)" "unprognostic (5.60e-2)" "unprognostic (4.65e-2)" "unprognostic (5.26e-2)" "unprognostic (1.27e-2)" "unprognostic (3.92e-1)" "unprognostic (8.09e-2)" "unprognostic (3.68e-2)" "unprognostic (1.83e-2)" "unprognostic (6.93e-3)" "unprognostic (1.67e-2)" "unprognostic (2.11e-1)" "unprognostic (4.22e-2)" "unprognostic (2.47e-2)" 0.2 0.0 0.2 2.5 0.5 0.0 1.0 0.2 0.3 2.3 0.1 20.6 100.5 0.4 1.2 0.3 1.0 12.1 0.0 0.3 0.3 17.4 12.9 0.2 0.1 0.4 0.5 0.0 5.6 0.0 0.0 0.1 0.3 0.6 19.6 0.0 0.4 0.4 0.0 0.0 114.6 0.9 0.4 0.1 8.1 3.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.3 1.1 4.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.3 16.1 0.0 2.2 0.0 1.8 0.0 2.0 0.0 0.0 0.0 1.8 0.0 0.0 2.9 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.5 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.3 0.3 10.0 4.8 0.0 0.0 0.3 2.7 0.1 0.3 1.6 0.3 0.1 0.0 0.2 0.2 5.5 0.0 0.3 0.1 0.1 0.0 1.1 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.2 0.3 0.3 0.3 0.4 0.5 0.3 0.4 0.3 0.3 0.0 0.0 1.1 39.8 0.5 0.0 0.6 0.4 2.2 0.0 1.3 0.5 0.2 17.2 1.5 3.7 0.0 0.0 0.0 51.0 5.9 3.2 3.1 3.6 0.2 0.0 16.3 0.0 0.5 4.3 0.0 0.1 8.2 3.2 0.0 0.0 0.0 10.7 0.0 0.0 0.6 32.3 2.0 0.0 0.0 5.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 26.2 0.6 5.6 54.3 0.0 0.0 1.6 165.3 18.5 8.1 0.0 0.0 0.1 0.4 4.8 0.0 0.4 0.0 0.0 0.2 0.0 36.9 2.9 HPD "4-HPPD, 4HPPD, GLOD3, PPD" ENSG00000158104 "4-hydroxyphenylpyruvate dioxygenase" P32754 12 121839527-121863596 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Dioxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 2530.4" "Group enriched" "Detected in some" 9 "Hepatocytes: 1373.6;Proximal tubular cells: 2144.0" "Cancer enriched" "Detected in many" 100 "liver cancer: 540.9" "Region enhanced" "Detected in many" "hippocampal formation: 7.8" "Immune cell enhanced" "Detected in some" "eosinophil: 7.8" "Group enriched" "Detected in many" 4 "dendritic cells: 3.8;granulocytes: 7.8" "Cell line enriched" "Detected in some" 31 "Hep G2: 516.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038321, HPA038322" Enhanced Uncertain "Nuclear speckles" NA NA 26000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA038321: AB_2675957, HPA038322: AB_10670778" "unprognostic (3.01e-2)" "unprognostic (2.30e-1)" "unprognostic (4.81e-3)" "unprognostic (1.42e-3)" "unprognostic (1.10e-2)" "unprognostic (9.08e-2)" "unprognostic (1.13e-2)" "unprognostic (8.84e-2)" "unprognostic (5.58e-2)" "unprognostic (6.14e-3)" "unprognostic (9.72e-3)" "unprognostic (8.61e-3)" "unprognostic (7.16e-2)" "unprognostic (1.97e-1)" "unprognostic (4.12e-1)" "unprognostic (3.06e-2)" "unprognostic (2.34e-1)" 2.3 5.3 0.6 0.7 0.4 0.9 4.6 3.2 0.6 2.0 119.0 1.2 0.1 4.1 0.7 0.7 6.4 1.1 3.5 7.8 0.5 531.0 2530.4 2.0 0.3 1.5 1.0 4.7 3.9 0.1 1.1 0.3 0.8 2.3 0.5 0.3 0.2 7.3 2.2 0.2 0.9 1.4 0.6 2.3 1.9 10.2 3.5 0.1 0.7 0.1 0.1 3.7 1.9 1.0 0.3 0.9 0.6 0.6 0.3 0.6 0.6 0.0 0.1 0.0 0.0 0.2 0.5 0.2 0.6 1.1 0.2 0.4 0.2 0.0 0.0 0.3 0.8 1.2 5.4 516.4 11.5 1.8 16.4 3.6 0.3 0.0 0.0 1.3 0.0 0.5 0.8 0.0 1.3 1.3 0.2 0.4 9.9 0.4 0.0 0.3 1.6 0.5 0.0 1.4 0.1 0.1 1.5 0.1 0.1 6.9 1.1 0.9 0.2 0.0 0.3 0.1 0.1 0.8 0.6 0.7 0.2 1.2 0.0 0.0 0.6 7.8 0.0 0.8 0.0 0.1 0.1 0.1 1.0 0.1 0.2 0.2 3.9 0.0 1.3 3.8 0.0 0.3 0.6 0.4 3.2 0.6 7.8 0.5 1.5 1.0 0.8 0.6 3.5 1.0 0.0 0.0 0.0 0.7 15.8 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.3 55.8 0.0 92.0 0.0 0.8 0.0 0.0 193.7 0.5 38.0 0.1 0.0 2.6 0.0 80.2 1.0 16.2 0.3 0.4 0.0 0.1 0.0 0.0 38.9 1373.6 0.3 0.0 1.0 0.0 0.0 37.8 0.3 121.0 2.5 10.8 0.0 0.0 0.4 0.0 0.0 1.5 0.7 0.2 0.0 5.3 0.0 0.0 0.0 2144.0 0.0 0.0 0.0 2.0 0.2 1.8 1.4 0.0 0.0 1.1 8.0 7.1 0.0 0.0 HS6ST2 ENSG00000171004 "Heparan sulfate 6-O-sulfotransferase 2" Q96MM7 X 132626016-132961395 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.5;kidney: 13.9;ovary: 14.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 35.7;Excitatory neurons: 37.5;Inhibitory neurons: 44.2;Leydig cells: 62.7;Oligodendrocyte precursor cells: 54.3;Peritubular cells: 35.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 46.2;HeLa: 28.1;RH-30: 66.1;RT4: 33.7;SH-SY5Y: 82.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA034625 Uncertain Approved "Golgi apparatus" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA034625: AB_10612119" "unprognostic (7.62e-3)" "unprognostic (4.89e-2)" "unprognostic (2.89e-1)" "unprognostic (1.41e-1)" "unprognostic (3.24e-1)" "unprognostic (5.54e-2)" "unprognostic (1.44e-1)" "unprognostic (1.71e-2)" "unprognostic (1.14e-2)" "unprognostic (2.13e-1)" "unprognostic (1.06e-1)" "unprognostic (3.57e-1)" "unprognostic (8.39e-5)" "unprognostic (1.36e-3)" "unprognostic (1.44e-1)" "unprognostic (2.54e-1)" "prognostic favorable (6.03e-4)" 0.2 2.4 12.4 0.6 10.0 0.0 2.0 1.2 7.4 1.0 0.0 0.6 0.1 3.5 2.4 3.9 1.8 0.3 0.2 9.6 10.7 13.9 0.0 0.7 0.1 6.3 22.5 14.1 5.3 0.3 1.1 8.4 7.3 2.8 0.8 1.5 0.9 0.8 6.2 0.2 0.1 1.5 4.9 0.0 0.9 2.9 20.3 0.6 0.4 0.9 0.5 2.5 0.7 2.6 10.7 0.1 14.5 0.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 17.0 0.0 0.0 15.2 0.0 0.0 0.5 21.7 0.1 0.0 0.0 46.2 0.1 28.1 0.0 0.0 0.0 0.0 0.7 20.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 7.8 0.3 0.1 11.8 7.2 0.6 0.0 66.1 0.0 13.3 33.7 1.8 82.0 14.8 0.0 0.1 23.7 0.0 0.1 0.0 0.0 2.6 9.6 23.8 0.0 0.1 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 12.4 10.0 1.2 7.4 9.6 10.7 6.3 22.5 7.3 4.9 20.3 2.6 0.0 0.0 0.0 1.6 0.0 0.3 0.2 1.8 6.8 0.2 4.3 2.4 0.8 0.0 5.5 3.7 0.0 35.7 0.2 0.3 5.9 0.0 0.5 0.3 0.6 0.5 0.0 0.0 37.5 2.0 2.6 2.6 0.0 0.1 0.0 0.1 0.0 0.0 3.4 0.0 44.2 0.2 2.0 0.0 0.0 1.1 62.7 0.2 0.0 10.3 0.0 5.3 0.0 54.3 1.4 0.8 0.2 35.3 0.0 1.3 0.0 0.1 9.8 0.4 0.0 17.9 0.3 0.3 1.1 11.1 0.3 17.4 0.1 0.3 0.2 1.8 HSD17B14 "DHRS10, retSDR3, SDR47C1" ENSG00000087076 "Hydroxysteroid 17-beta dehydrogenase 14" Q9BPX1 19 48813018-48836510 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 78.2;Hofbauer cells: 149.9;Proximal tubular cells: 434.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "B-cells: 3.7;NK-cells: 4.7;T-cells: 3.1" "Cell line enhanced" "Detected in many" "GAMG: 53.9;HHSteC: 49.5;hTERT-RPE1: 37.9;Karpas-707: 50.7;RT4: 40.5" "Not detected" "Not detected" HPA021467 Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA021467: AB_1847652" "unprognostic (2.03e-1)" "unprognostic (7.94e-3)" "prognostic unfavorable (4.39e-5)" "unprognostic (4.32e-2)" "unprognostic (8.03e-2)" "unprognostic (1.47e-1)" "unprognostic (7.54e-2)" "unprognostic (7.76e-3)" "unprognostic (2.71e-1)" "unprognostic (4.04e-1)" "prognostic favorable (2.87e-5)" "unprognostic (4.56e-1)" "unprognostic (5.50e-3)" "unprognostic (9.05e-3)" "unprognostic (1.01e-1)" "unprognostic (5.51e-2)" "unprognostic (1.81e-2)" 9.2 39.5 38.1 3.2 36.3 1.2 11.2 42.8 47.7 34.1 72.5 10.5 3.3 31.6 5.6 4.2 22.7 11.6 8.1 37.2 38.2 58.2 78.8 13.1 8.0 35.6 41.2 56.2 6.2 46.7 24.1 7.3 35.3 15.0 1.9 10.0 6.4 9.2 1.3 7.7 8.2 8.5 35.8 8.7 8.6 4.8 43.6 9.6 25.3 2.2 3.8 15.8 14.6 37.0 0.1 14.0 14.1 2.4 15.8 2.6 0.3 2.6 19.9 1.1 1.2 13.4 0.2 8.0 14.2 0.6 53.9 0.1 1.3 0.1 1.3 0.5 1.0 4.1 0.3 1.8 49.5 0.0 20.9 19.0 0.5 1.2 0.5 37.9 18.1 4.8 0.1 50.7 0.1 0.5 1.1 0.4 1.2 8.2 9.3 7.9 0.1 1.5 0.0 40.5 3.5 9.0 0.0 1.8 10.9 6.0 0.4 0.5 0.0 0.3 5.2 0.5 0.1 8.9 18.9 0.6 11.9 1.2 0.1 0.0 0.0 0.0 0.9 0.0 1.5 3.7 1.5 0.7 0.0 2.5 3.1 2.3 0.0 4.7 0.0 0.5 0.5 0.8 38.1 36.3 42.8 47.7 37.2 38.2 35.6 41.2 35.3 35.8 43.6 37.0 3.3 3.2 11.5 21.5 6.0 2.5 3.6 1.7 0.0 5.5 1.3 5.0 2.0 1.5 4.4 7.3 0.0 1.4 0.3 0.0 78.2 1.9 0.4 0.3 3.5 8.2 13.2 5.3 5.0 1.1 3.0 14.1 2.0 0.7 7.0 7.4 28.5 32.0 149.9 11.8 5.0 0.3 8.2 13.4 9.5 1.4 4.1 17.3 21.4 6.5 8.0 53.5 1.0 4.5 0.8 2.6 0.0 7.2 0.1 3.8 2.2 434.5 0.7 1.6 0.0 2.4 2.9 5.6 15.7 0.3 1.8 2.2 2.8 7.5 0.2 2.9 HSD17B3 SDR12C2 ENSG00000130948 "Hydroxysteroid 17-beta dehydrogenase 3" P37058 9 96235306-96302176 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Disease variant, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 15.1;testis: 36.7" "Group enriched" "Detected in some" 6 "Leydig cells: 108.1;Oligodendrocytes: 93.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 2.3;HEL: 1.0;U-2 OS: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA056833 Enhanced Approved Vesicles NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA056833: AB_2683252" "unprognostic (2.78e-1)" "unprognostic (6.61e-3)" "unprognostic (1.03e-1)" "unprognostic (5.76e-2)" "unprognostic (1.15e-1)" "unprognostic (1.55e-1)" "unprognostic (3.08e-2)" "unprognostic (6.15e-2)" "unprognostic (1.74e-1)" "unprognostic (5.13e-2)" "unprognostic (3.26e-4)" "unprognostic (3.45e-1)" "unprognostic (5.48e-8)" "unprognostic (8.47e-3)" "unprognostic (1.15e-1)" "unprognostic (7.24e-2)" "unprognostic (3.11e-2)" 1.6 0.8 3.1 0.2 4.3 0.0 1.7 3.4 5.9 3.1 2.4 2.7 0.5 1.5 0.9 0.7 3.5 0.2 2.1 3.1 3.6 4.7 15.1 1.8 0.0 4.3 3.9 1.4 4.2 0.0 1.7 0.1 4.2 3.2 0.1 0.7 1.0 0.1 0.5 0.9 3.7 0.0 3.3 0.9 1.4 36.7 4.2 0.1 10.0 0.1 0.0 1.6 1.8 5.4 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.3 0.0 0.0 0.0 1.0 0.0 0.1 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.1 4.3 3.4 5.9 3.1 3.6 4.3 3.9 4.2 3.3 4.2 5.4 0.0 0.0 0.0 15.3 0.2 0.0 0.1 0.8 0.0 0.2 0.1 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.2 4.0 0.2 0.0 0.4 1.8 0.0 0.5 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.0 2.5 0.0 0.0 0.5 0.5 0.0 0.0 0.4 14.4 108.1 1.1 0.0 4.7 0.1 0.6 0.0 1.0 93.2 0.2 0.1 12.8 0.0 0.1 0.6 0.0 0.5 0.2 0.0 0.1 0.5 1.9 1.8 0.0 0.3 0.1 0.0 0.0 0.3 0.0 HTRA1 "ARMD7, HtrA, IGFBP5-protease, PRSS11" ENSG00000166033 "HtrA serine peptidase 1" Q92743 10 122458551-122514907 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 269.3;Granulosa cells: 731.6;Horizontal cells: 625.9;Muller glia cells: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 2417.8;ASC TERT1: 889.4;fHDF/TERT166: 862.3;HSkMC: 1581.4;LHCN-M2: 1238.2;U-87 MG: 1004.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036655 Approved Supported "Plasma membrane" "Secreted to blood" NA NA 24800000 7600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "HPA036655: AB_10671966" "unprognostic (3.84e-1)" "unprognostic (3.42e-2)" "unprognostic (1.57e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-3)" "unprognostic (8.71e-3)" "unprognostic (2.33e-2)" "unprognostic (3.83e-1)" "unprognostic (7.22e-2)" "unprognostic (3.36e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (7.90e-7)" "unprognostic (7.12e-3)" "unprognostic (9.13e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.62e-6)" 246.0 81.3 382.1 37.0 436.6 0.5 202.8 422.6 595.7 352.1 316.2 154.8 20.8 197.1 247.1 57.8 122.9 301.2 114.7 377.7 411.4 230.9 226.4 69.9 39.9 427.1 447.0 425.5 55.9 111.8 184.1 281.9 425.3 85.7 51.8 243.6 101.1 114.5 31.1 130.5 73.5 152.3 382.1 54.2 87.3 19.5 423.6 21.2 78.8 80.9 27.3 137.3 188.3 464.2 0.3 45.6 19.4 5.7 2417.8 889.4 0.8 108.3 196.8 44.4 23.6 0.2 0.6 0.0 29.0 862.3 68.6 12.8 7.6 124.4 6.2 0.1 4.9 0.1 65.4 0.3 123.7 0.1 0.9 1581.4 444.6 25.8 205.3 503.6 207.1 0.0 0.1 1.5 1238.2 22.3 0.1 0.7 20.9 0.2 67.6 0.2 1.3 0.4 282.6 2.2 1.2 3.9 272.1 0.2 122.2 91.4 8.6 0.2 136.0 309.9 4.5 141.3 94.1 0.2 0.1 0.3 1004.6 0.2 148.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 382.1 436.6 422.6 595.7 377.7 411.4 427.1 447.0 425.3 382.1 423.6 464.2 55.1 22.4 6.9 116.5 0.9 44.1 32.5 10.8 23.9 53.3 5.4 31.2 26.4 14.3 0.9 64.4 54.2 30.9 1.3 0.0 0.0 2.0 3.5 11.3 76.5 107.0 0.0 2.7 2.2 4.6 164.6 269.3 4.6 14.4 1.3 731.6 57.8 157.8 51.3 625.9 31.2 0.3 8.2 18.1 59.9 4.2 31.7 22.0 46.2 86.2 8.5 373.8 0.0 193.0 112.5 2.7 1.3 77.5 1.9 8.7 0.2 22.6 10.1 150.3 6.6 63.3 140.5 0.2 0.7 7.0 30.5 87.7 7.2 2.5 0.6 11.9 IGF2BP1 IMP-1 ENSG00000159217 "Insulin like growth factor 2 mRNA binding protein 1" Q9NZI8 17 48997385-49056145 "Predicted intracellular proteins" "mRNA transport, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 5.5;testis: 4.8" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 37.3;Spermatocytes: 30.4;Spermatogonia: 21.7" "Cancer enriched" "Detected in many" 16 "testis cancer: 28.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 146.7;CACO-2: 238.7;Hep G2: 112.0;K-562: 124.4;NTERA-2: 117.6;REH: 140.0;SuSa: 111.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021367, HPA062273" Enhanced Supported Cytosol NA NA 13000 "Cluster 28: Placenta - Pregnancy" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" Cytosol "HPA021367: AB_1851480, HPA062273: AB_2684733" "unprognostic (6.79e-4)" "unprognostic (2.76e-1)" "unprognostic (4.86e-3)" "unprognostic (2.30e-6)" "unprognostic (1.95e-2)" "unprognostic (9.11e-3)" "unprognostic (1.80e-2)" "unprognostic (1.01e-2)" "unprognostic (9.55e-3)" "unprognostic (2.58e-1)" "unprognostic (2.86e-2)" "unprognostic (5.91e-2)" "unprognostic (2.80e-6)" "unprognostic (2.58e-2)" "unprognostic (1.55e-1)" "unprognostic (2.32e-3)" "unprognostic (1.47e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 59.5 146.7 0.1 5.2 7.6 105.0 8.5 0.2 12.1 20.1 238.7 4.0 12.4 0.9 1.0 3.6 0.0 91.4 0.0 21.1 0.0 52.9 91.3 33.6 112.0 6.9 48.8 23.6 10.4 0.0 2.9 0.2 4.1 24.9 16.6 124.4 0.0 16.6 0.9 0.1 42.9 117.6 0.2 0.2 140.0 48.3 0.0 0.0 0.1 0.0 0.0 5.1 0.1 3.6 111.4 0.2 13.5 0.5 0.0 1.4 12.5 0.0 0.1 0.1 80.7 0.1 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.4 1.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.1 5.5 0.0 0.6 0.0 0.0 3.5 0.2 0.0 0.0 0.0 5.3 0.1 0.1 3.9 0.0 2.7 0.2 0.0 37.3 3.7 0.0 0.1 1.3 0.0 0.0 0.0 6.9 0.0 0.2 0.0 0.0 0.0 0.8 4.4 0.3 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 1.1 0.0 0.0 0.1 0.0 5.3 0.7 0.0 0.0 1.1 1.1 30.4 21.7 0.0 0.1 2.9 0.3 0.1 0.0 0.3 IGSF11 "BT-IgSF, CT119, Igsf13, MGC35227, VSIG3" ENSG00000144847 "Immunoglobulin superfamily member 11" Q5DX21 3 118900557-119146068 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Growth regulation" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 46.3;ovary: 16.2;retina: 50.6;testis: 35.7" "Cell type enhanced" "Detected in many" "Astrocytes: 133.9;Early spermatids: 257.9;Inhibitory neurons: 139.1;Late spermatids: 334.0;Oligodendrocytes: 283.2" "Group enriched" "Detected in many" 9 "glioma: 9.2;melanoma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 8.0;HEL: 5.9;SK-MEL-30: 35.1;U-266/70: 11.9;U-266/84: 15.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046377 Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Cell Junctions" "Nucleoplasm, Cytosol" "HPA046377: AB_10966195" "unprognostic (2.05e-1)" "unprognostic (1.29e-1)" "unprognostic (1.62e-1)" "unprognostic (1.88e-1)" "unprognostic (1.17e-2)" "unprognostic (1.89e-3)" "unprognostic (2.51e-2)" "unprognostic (3.56e-2)" "unprognostic (3.91e-1)" "unprognostic (1.44e-1)" "unprognostic (2.20e-1)" "unprognostic (8.70e-2)" "unprognostic (1.08e-1)" "unprognostic (5.03e-4)" "unprognostic (1.39e-1)" "unprognostic (3.42e-2)" "unprognostic (7.57e-2)" 0.3 7.8 19.5 0.4 34.0 0.0 0.2 26.9 22.2 0.8 1.5 4.1 0.2 0.5 1.1 1.2 0.6 0.8 2.2 19.3 18.6 8.2 0.1 0.1 0.1 30.5 28.0 16.2 3.7 1.3 1.7 0.1 29.9 0.7 0.8 50.6 0.6 0.8 3.9 1.5 0.9 0.5 23.3 0.1 1.6 35.7 25.6 0.3 3.4 5.0 0.2 0.6 0.8 46.3 0.0 8.0 0.2 0.1 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.9 2.7 0.0 0.0 0.0 0.1 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.7 0.6 0.0 0.1 35.1 2.1 0.7 0.1 0.0 0.0 1.4 0.0 0.1 11.9 15.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 34.0 26.9 22.2 19.3 18.6 30.5 28.0 29.9 23.3 25.6 46.3 0.1 0.0 0.0 133.9 0.6 0.4 0.1 0.3 2.8 9.1 0.3 0.1 1.3 0.0 0.5 0.0 75.0 0.2 0.1 0.0 0.0 0.9 257.9 4.2 0.8 0.3 0.0 0.0 77.8 0.7 0.0 2.0 0.0 7.2 0.0 26.8 0.0 0.0 0.0 16.8 139.1 0.0 6.1 0.0 0.4 334.0 3.7 0.4 3.6 4.7 0.0 22.3 0.0 43.2 283.2 0.2 0.0 1.9 0.2 0.1 0.0 5.9 0.4 25.7 0.0 0.8 0.9 22.4 6.0 0.7 0.0 0.1 0.2 6.8 0.0 0.4 IGSF21 "MGC15730, RP11-121A23.1" ENSG00000117154 "Immunoglobin superfamily member 21" Q96ID5 1 18107798-18378483 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 51.7" "Group enriched" "Detected in some" 4 "Bipolar cells: 177.8;Excitatory neurons: 82.2;Microglial cells: 74.9;Oligodendrocyte precursor cells: 141.3" "Group enriched" "Detected in many" 5 "breast cancer: 4.1;glioma: 8.6;prostate cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 19.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 23000 "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.87e-1)" "unprognostic (1.73e-1)" "unprognostic (1.50e-3)" "unprognostic (7.06e-2)" "unprognostic (3.29e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "unprognostic (1.66e-2)" "unprognostic (7.87e-2)" "unprognostic (2.77e-3)" "unprognostic (4.34e-2)" "unprognostic (2.33e-1)" "unprognostic (7.85e-4)" "unprognostic (3.76e-5)" "unprognostic (2.10e-1)" "unprognostic (1.23e-2)" "unprognostic (2.63e-2)" 2.2 4.8 29.6 0.4 35.8 0.4 3.0 41.4 51.7 1.7 9.2 1.0 0.0 1.0 0.4 0.9 1.0 0.8 1.0 37.4 17.6 1.1 0.4 1.5 0.2 26.9 23.4 0.6 1.9 10.4 1.6 1.4 27.0 3.8 0.3 9.4 1.1 1.1 0.3 0.8 0.4 0.3 21.6 13.0 0.6 0.8 24.5 0.8 0.6 0.4 0.7 3.9 1.1 33.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.6 35.8 41.4 51.7 37.4 17.6 26.9 23.4 27.0 21.6 24.5 33.5 0.1 0.0 0.0 3.6 0.6 0.3 0.2 0.0 0.0 177.8 9.2 2.7 0.6 1.5 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 5.9 0.0 0.0 1.8 3.0 0.0 82.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.7 28.9 0.1 0.0 23.6 4.0 12.8 0.6 12.8 0.0 74.9 0.0 6.3 0.0 141.3 2.4 0.1 1.3 0.0 0.0 0.9 0.0 0.0 0.0 13.0 6.6 4.5 0.2 0.4 0.6 0.0 0.1 0.0 0.0 0.0 0.2 0.2 IL17RB "CRL4, EVI27, IL17BR, IL17RH1" ENSG00000056736 "Interleukin 17 receptor B" Q9NRM6 3 53846568-53865794 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.9;kidney: 59.8;liver: 33.3" "Cell type enhanced" "Detected in many" "Astrocytes: 48.3;Enteroendocrine cells: 29.2;Oligodendrocyte precursor cells: 37.7;Proximal tubular cells: 78.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 20.2;Hep G2: 59.5;OE19: 46.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005482 Enhanced Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" "HPA005482: AB_1234567" "unprognostic (1.85e-3)" "unprognostic (4.22e-3)" "unprognostic (1.60e-3)" "unprognostic (2.86e-2)" "unprognostic (1.42e-2)" "unprognostic (6.20e-3)" "unprognostic (1.62e-2)" "unprognostic (6.09e-3)" "unprognostic (1.30e-1)" "unprognostic (5.41e-2)" "unprognostic (4.75e-2)" "unprognostic (4.27e-2)" "prognostic favorable (6.61e-4)" "unprognostic (8.10e-2)" "unprognostic (6.97e-2)" "unprognostic (5.29e-1)" "unprognostic (7.15e-3)" 0.9 2.0 20.2 2.3 21.4 0.5 5.7 22.7 28.9 18.1 16.6 6.8 5.8 5.1 0.7 1.7 3.3 2.4 2.7 19.4 20.2 59.8 33.3 3.8 2.5 18.7 19.9 1.5 7.8 1.1 4.2 0.9 19.0 2.4 6.9 4.8 4.9 0.6 1.3 2.2 5.9 0.8 18.9 1.2 3.6 2.5 23.2 0.3 2.9 0.2 0.7 0.8 1.3 23.6 1.5 3.1 4.5 3.4 0.1 0.0 7.1 3.1 0.1 0.1 0.0 20.2 1.4 4.6 1.0 1.0 1.7 0.8 12.2 0.0 0.0 1.6 3.5 6.0 6.1 59.5 0.0 5.6 3.2 0.0 0.0 0.0 0.0 3.8 0.0 1.6 4.9 2.1 0.1 4.2 0.9 2.3 12.1 46.2 2.6 1.7 1.9 5.3 1.4 5.3 6.4 3.7 10.1 2.4 1.9 3.3 9.2 2.0 2.5 3.0 3.3 2.6 3.9 4.7 5.6 2.9 2.7 3.3 1.7 1.3 0.2 0.0 0.2 0.2 0.1 0.1 0.6 0.2 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.3 0.9 0.1 20.2 21.4 22.7 28.9 19.4 20.2 18.7 19.9 19.0 18.9 23.2 23.6 0.2 0.0 4.1 48.3 0.2 0.3 2.0 0.0 0.0 0.1 8.2 4.4 4.1 17.2 1.3 0.0 0.0 1.4 0.3 4.3 9.8 4.8 1.0 0.5 1.0 0.2 29.2 0.0 0.5 1.6 1.0 0.6 4.6 1.7 2.5 0.4 0.4 13.1 0.1 0.0 2.5 8.7 2.0 0.0 1.1 0.7 1.2 1.2 0.0 1.9 0.0 4.4 0.0 37.7 4.3 1.8 3.0 0.4 0.0 4.4 2.9 78.0 0.0 0.1 0.0 0.3 0.5 0.4 1.0 0.0 0.1 0.4 0.9 0.0 10.2 0.6 IYD "C6orf71, DEHAL1, dJ422F24.1" ENSG00000009765 "Iodotyrosine deiodinase" Q6PHW0 6 150368892-150405969 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" Oxidoreductase "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "thyroid gland: 472.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 23.7;Hepatocytes: 25.1;Intestinal goblet cells: 21.8;Paneth cells: 22.5;Proximal enterocytes: 89.1;Proximal tubular cells: 35.4" "Cancer enriched" "Detected in many" 20 "thyroid cancer: 80.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 1.9" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 7 "CACO-2: 1.3;OE19: 3.0;SK-BR-3: 3.2" "Group enriched" "Detected in some" 13 "hippocampal formation: 7.4;thalamus: 2.4" "Low region specificity" "Detected in all" HPA059627 Enhanced Supported "Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 1: Thyroid gland - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA059627: AB_2684086" "unprognostic (3.73e-4)" "unprognostic (2.93e-2)" "unprognostic (5.97e-2)" "unprognostic (1.95e-2)" "unprognostic (1.55e-1)" "unprognostic (2.98e-2)" "prognostic favorable (6.22e-4)" "unprognostic (1.11e-1)" "unprognostic (3.80e-2)" "unprognostic (1.17e-1)" "unprognostic (7.41e-2)" "unprognostic (1.02e-1)" "unprognostic (3.07e-9)" "unprognostic (9.79e-3)" "unprognostic (2.04e-1)" "unprognostic (2.03e-2)" "unprognostic (2.18e-2)" 0.1 0.0 0.4 0.6 0.3 0.3 0.5 0.6 0.6 0.1 0.2 6.4 18.1 0.2 0.6 0.0 0.0 8.9 0.5 0.3 0.1 26.6 33.6 0.7 0.5 0.5 0.4 0.0 0.4 0.0 0.0 0.0 0.6 0.2 6.5 0.2 0.1 0.0 0.0 0.2 19.6 0.2 0.0 0.1 2.0 0.2 0.5 0.0 472.7 0.0 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 3.0 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 3.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 1.6 0.5 0.3 0.2 0.4 0.2 0.2 0.1 0.1 0.0 0.4 0.2 0.2 1.9 0.7 0.2 0.3 0.2 1.3 0.4 0.3 0.6 0.6 0.3 0.1 0.5 0.4 0.6 0.0 0.5 0.5 0.7 3.2 7.8 0.0 0.0 0.1 0.6 0.2 0.0 0.1 0.3 0.4 0.8 14.3 8.9 0.0 0.0 0.1 0.0 23.7 1.9 0.3 0.0 0.9 0.3 0.4 3.6 2.7 0.1 0.2 0.0 0.7 0.0 2.2 1.3 0.1 1.1 25.1 0.1 0.0 0.1 21.8 0.0 0.0 1.2 0.1 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 22.5 0.0 0.0 1.0 89.1 35.4 3.6 1.3 0.0 1.7 0.3 0.1 0.1 0.0 0.4 0.3 0.9 0.4 11.5 0.7 KANK3 "ANKRD47, FLJ46061" ENSG00000186994 "KN motif and ankyrin repeat domains 3" Q6NY19 19 8322584-8343262 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 196.2;Endothelial cells: 83.8;Hepatic stellate cells: 55.3" "Cancer enhanced" "Detected in all" "testis cancer: 7.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 4 "NK-cells: 1.2;T-cells: 1.0" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 8.1;TIME: 14.8;U-266/70: 5.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "olfactory bulb: 16.2" HPA051153 Approved Approved "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA051153: AB_2681365" "unprognostic (1.56e-1)" "unprognostic (1.63e-4)" "unprognostic (1.54e-2)" "unprognostic (8.95e-3)" "unprognostic (1.07e-1)" "unprognostic (2.84e-3)" "unprognostic (1.82e-3)" "unprognostic (3.26e-2)" "unprognostic (1.19e-1)" "unprognostic (1.39e-2)" "unprognostic (1.34e-2)" "unprognostic (4.77e-1)" "prognostic favorable (1.69e-5)" "unprognostic (5.03e-2)" "unprognostic (1.67e-1)" "unprognostic (2.86e-1)" "unprognostic (3.24e-1)" 25.6 7.6 12.0 2.3 9.7 0.6 26.1 9.6 12.2 8.2 5.8 6.2 2.9 10.2 0.7 5.1 11.2 2.5 32.9 8.7 8.9 22.2 4.2 33.4 2.8 12.5 11.5 3.6 3.9 1.5 6.9 14.6 11.5 7.6 0.5 0.3 4.1 1.8 13.7 6.7 7.3 2.4 9.7 35.5 6.2 2.4 13.2 0.7 15.5 6.0 0.8 7.9 6.8 8.9 0.1 0.6 0.2 0.5 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.7 0.2 0.0 2.3 0.0 0.0 0.1 0.5 2.6 0.0 0.7 1.4 0.3 0.3 0.4 0.1 0.2 1.3 0.0 0.8 0.0 0.0 0.0 8.1 0.6 0.0 0.3 0.0 0.4 0.0 0.4 0.5 0.5 0.2 1.4 0.0 0.7 0.1 0.1 0.0 0.1 0.0 0.7 0.1 0.0 0.5 0.0 14.8 0.0 1.3 0.3 0.1 5.9 0.2 0.3 0.1 0.1 0.2 0.2 0.1 0.0 1.0 0.0 0.5 0.1 0.5 0.1 0.0 0.1 0.2 0.4 0.2 1.2 0.0 0.0 0.4 0.2 12.0 9.7 9.6 12.2 8.7 8.9 12.5 11.5 11.5 9.7 13.2 8.9 196.2 6.4 3.2 2.0 0.3 2.5 0.4 0.6 0.6 0.3 1.5 2.5 2.2 0.0 0.8 0.0 4.2 0.4 3.8 0.1 5.9 0.1 6.6 0.5 0.7 83.8 0.0 2.7 0.6 1.8 0.3 6.4 1.5 0.8 0.0 0.2 55.3 1.0 0.5 0.0 0.9 0.0 0.0 1.3 2.1 8.1 0.6 0.9 5.4 18.7 0.0 0.4 12.3 0.5 1.6 0.6 0.1 0.4 0.4 1.0 0.0 0.4 0.7 0.7 19.7 8.3 12.9 6.5 3.6 1.1 1.3 0.3 2.8 4.0 0.1 0.8 KCNAB2 "AKR6A5, HKvbeta2.1, HKvbeta2.2, KCNA2B" ENSG00000069424 "Potassium voltage-gated channel subfamily A regulatory beta subunit 2" Q13303 1 5990927-6101193 "Plasma proteins, Predicted intracellular proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 188.3" "Cell type enhanced" "Detected in many" "dendritic cells: 50.3;Excitatory neurons: 67.8;Hofbauer cells: 63.6;Inhibitory neurons: 49.2;Kupffer cells: 86.2;Macrophages: 51.3;Melanocytes: 64.0;NK-cells: 51.5" "Cancer enriched" "Detected in all" 7 "melanoma: 29.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 278.8;JURKAT: 142.7;U-937: 289.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB001975 Enhanced NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 10: Brain - Neuronal signaling" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB001975: " "unprognostic (6.60e-2)" "unprognostic (2.33e-2)" "unprognostic (3.97e-3)" "unprognostic (2.30e-2)" "unprognostic (1.76e-2)" "unprognostic (8.18e-3)" "unprognostic (4.30e-2)" "unprognostic (1.05e-1)" "unprognostic (4.85e-2)" "unprognostic (1.58e-2)" "unprognostic (7.71e-3)" "unprognostic (8.83e-3)" "prognostic unfavorable (3.50e-5)" "unprognostic (2.88e-2)" "unprognostic (3.10e-2)" "unprognostic (2.35e-1)" "unprognostic (5.24e-2)" 12.8 7.7 69.2 28.6 94.1 63.8 8.0 7.4 188.3 5.6 0.0 8.8 5.4 7.2 2.3 5.0 8.6 11.2 22.1 141.6 12.8 26.0 10.1 31.1 43.6 78.7 5.3 5.6 4.0 1.5 20.3 5.9 77.5 6.2 4.6 17.8 6.4 3.4 12.6 12.3 23.9 6.3 1.5 65.8 6.5 5.6 18.9 27.0 6.2 15.8 24.7 8.8 5.1 89.7 11.3 27.0 2.5 4.5 1.5 5.0 10.3 6.3 40.0 6.3 7.8 10.6 4.1 62.0 23.3 6.1 7.7 5.4 2.7 1.0 3.2 84.6 9.6 71.1 25.3 21.1 6.0 278.8 1.9 6.5 1.3 3.4 7.5 6.3 3.6 142.7 2.7 114.2 3.1 9.8 61.9 115.9 1.1 3.9 15.4 13.8 9.7 78.9 0.1 0.2 20.6 6.2 5.3 6.4 101.0 2.7 5.4 117.3 1.1 1.3 9.4 14.4 7.5 84.4 122.4 100.4 12.7 289.2 1.9 4.4 34.3 18.6 29.8 27.2 26.8 7.5 18.2 28.0 31.0 8.7 18.7 20.6 14.4 19.4 25.0 12.7 19.1 43.2 69.2 94.1 7.4 188.3 141.6 12.8 78.7 5.3 77.5 1.5 18.9 89.7 3.0 0.0 6.6 7.5 23.0 4.8 1.7 1.8 1.8 24.0 1.2 2.3 15.7 7.2 1.5 1.8 6.2 0.5 50.3 0.3 0.0 0.3 5.8 3.4 1.9 3.1 0.0 11.1 67.8 1.4 2.3 3.5 2.0 0.6 8.8 2.9 3.9 1.0 63.6 6.7 49.2 0.5 2.0 86.2 19.0 5.2 3.7 51.3 64.0 5.6 26.6 4.9 51.5 8.5 6.1 0.6 0.1 2.6 23.4 0.4 0.1 40.8 8.7 11.8 0.0 2.1 3.1 3.2 2.9 0.7 2.8 0.8 44.3 2.5 0.3 0.6 KCNH6 "erg2, HERG2, Kv11.2" ENSG00000173826 "Potassium voltage-gated channel subfamily H member 6" Q9H252 17 63523334-63548977 "FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.8;kidney: 7.0;pituitary gland: 5.3;prostate: 3.9;retina: 4.4" "Group enriched" "Detected in some" 8 "Bipolar cells: 44.8;Cardiomyocytes: 25.6;Cone photoreceptor cells: 31.3;Enteroendocrine cells: 34.6;Proximal enterocytes: 40.3;Proximal tubular cells: 14.1" "Cancer enhanced" "Detected in some" "prostate cancer: 5.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "SCLC-21H: 3.3;SH-SY5Y: 1.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "medulla oblongata: 1.1;olfactory bulb: 2.4;spinal cord: 2.5" HPA061704 Approved NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA061704: " "unprognostic (8.00e-2)" "unprognostic (1.80e-1)" "unprognostic (5.46e-2)" "unprognostic (5.68e-2)" "unprognostic (5.98e-5)" "unprognostic (3.39e-1)" "unprognostic (1.15e-1)" "unprognostic (3.03e-1)" "unprognostic (1.28e-2)" "unprognostic (3.25e-1)" "unprognostic (1.74e-3)" "unprognostic (3.95e-1)" "unprognostic (1.19e-1)" "unprognostic (9.80e-2)" "unprognostic (3.66e-1)" "unprognostic (8.05e-2)" "unprognostic (9.15e-2)" 0.0 0.1 0.9 0.0 1.1 0.2 0.0 0.9 1.1 0.0 0.3 0.2 2.2 0.0 0.0 0.0 0.1 0.0 0.0 0.6 1.6 7.0 0.0 0.3 0.0 1.6 1.5 0.0 1.3 0.0 5.3 0.1 1.7 3.9 0.2 4.4 0.0 0.0 0.1 0.1 4.8 0.0 1.1 0.1 0.8 1.2 1.5 0.7 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.3 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 1.1 0.9 1.1 0.6 1.6 1.6 1.5 1.7 1.1 1.5 1.1 0.0 0.0 0.0 0.3 0.0 0.3 0.2 0.0 0.0 44.8 0.0 0.3 25.6 0.0 0.0 0.0 31.3 0.0 0.0 0.1 0.0 0.0 3.0 0.6 0.1 1.3 34.6 0.0 1.1 0.0 0.0 0.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.9 3.8 0.0 0.0 0.0 3.4 0.0 0.1 1.8 0.0 0.0 1.1 0.0 0.5 0.1 0.1 1.2 0.0 0.0 1.4 40.3 14.1 0.0 3.1 0.0 0.2 1.0 0.0 0.7 0.0 0.1 0.1 0.1 0.0 0.8 0.1 KCNK10 "K2p10.1, PPP1R97, TREK-2, TREK2" ENSG00000100433 "Potassium two pore domain channel subfamily K member 10" P57789 14 88180103-88326907 "Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1;intestine: 5.1;stomach 1: 2.6" "Group enriched" "Detected in some" 4 "dendritic cells: 12.5;Excitatory neurons: 43.8;Inhibitory neurons: 17.0;Oligodendrocyte precursor cells: 37.7;Oligodendrocytes: 11.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 62 "plasmacytoid DC: 10.0" "Lineage enriched" "Detected in single" 100 "dendritic cells: 10.0" "Cell line enhanced" "Detected in some" "OE19: 1.5;REH: 1.7;SCLC-21H: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030462 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA030462: AB_10601919" "unprognostic (9.52e-3)" "unprognostic (1.17e-1)" "unprognostic (1.94e-2)" "unprognostic (1.08e-1)" "unprognostic (8.20e-2)" "unprognostic (1.45e-1)" "unprognostic (1.18e-1)" "unprognostic (2.25e-1)" "unprognostic (4.58e-1)" "unprognostic (1.23e-2)" "unprognostic (2.70e-1)" "unprognostic (2.45e-1)" "unprognostic (6.97e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-2)" "unprognostic (1.29e-1)" "unprognostic (4.26e-3)" 0.0 0.3 4.0 0.4 3.6 0.2 0.0 5.1 4.1 0.2 0.0 1.3 5.1 0.0 0.0 1.1 0.0 0.0 0.0 4.4 2.9 2.4 0.0 0.1 0.1 4.2 2.9 0.0 1.4 0.0 0.5 0.0 3.5 0.0 0.7 0.1 0.2 0.0 0.0 0.0 2.6 0.1 2.3 0.1 2.6 0.5 2.4 0.0 0.0 0.0 0.4 0.0 0.2 4.6 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.5 0.1 1.7 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.1 4.0 3.6 5.1 4.1 4.4 2.9 4.2 2.9 3.5 2.3 2.4 4.6 0.0 0.0 0.0 0.7 0.1 0.6 0.0 0.0 1.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 12.5 2.1 0.0 0.0 0.7 0.0 0.0 0.1 1.8 0.0 43.8 0.6 0.0 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 17.0 1.6 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 37.7 11.9 0.1 0.3 0.0 0.0 0.0 1.5 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.7 3.2 0.0 0.0 0.1 0.0 1.6 0.1 KDR "CD309, FLK1, VEGFR, VEGFR2" ENSG00000128052 "Kinase insert domain receptor" P35968 4 55078481-55125595 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 9 "Adipocytes: 157.8;Endothelial cells: 143.8;Hepatic stellate cells: 158.1;Muller glia cells: 206.6" "Cancer enhanced" "Detected in all" "renal cancer: 27.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 74.8;TIME: 83.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004028, HPA073577" Enhanced Approved "Nuclear membrane,Vesicles" "Intracellular and membrane" NA NA 11000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Nuclear membrane" "CAB004028: AB_2212507, HPA073577: " "unprognostic (1.61e-1)" "unprognostic (2.03e-1)" "unprognostic (9.65e-2)" "unprognostic (1.97e-1)" "unprognostic (9.63e-2)" "unprognostic (1.22e-2)" "unprognostic (1.78e-3)" "unprognostic (2.59e-2)" "unprognostic (1.19e-2)" "unprognostic (1.10e-1)" "unprognostic (8.79e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (7.26e-4)" "unprognostic (4.00e-2)" "unprognostic (2.30e-1)" "unprognostic (3.22e-1)" "unprognostic (1.86e-1)" 41.6 11.7 2.7 4.3 3.8 0.0 26.1 2.8 4.1 14.8 10.4 6.3 2.2 39.5 2.9 4.0 17.9 5.6 20.6 2.1 2.8 15.7 9.2 23.5 2.8 3.2 3.6 5.2 6.2 8.6 11.0 30.9 3.5 11.7 1.0 16.4 5.3 10.0 6.5 5.9 7.5 7.5 3.3 4.4 8.4 1.8 4.5 1.0 34.4 4.6 1.0 8.6 7.5 3.4 0.0 0.0 4.4 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 8.5 0.0 0.0 0.9 0.0 0.0 0.4 0.2 74.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.4 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.8 2.8 4.1 2.1 2.8 3.2 3.6 3.5 3.3 4.5 3.4 157.8 0.0 4.9 0.0 1.4 2.5 0.5 0.1 1.8 11.7 1.3 2.5 9.4 1.5 18.4 0.0 0.0 0.1 0.8 0.0 0.0 0.5 0.8 0.4 2.6 143.8 0.0 2.7 0.1 0.0 0.1 8.3 0.0 0.8 2.5 0.0 158.1 3.3 0.4 0.0 1.3 0.0 0.0 10.6 2.1 0.9 0.0 1.2 7.2 7.5 0.0 206.6 0.0 0.0 6.1 0.5 0.0 0.4 1.3 0.5 0.0 0.0 3.9 7.9 0.0 0.9 7.5 0.3 0.9 0.8 2.7 0.1 0.6 1.6 0.0 1.4 KHK ENSG00000138030 Ketohexokinase P50053 2 27086747-27100762 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 14 "intestine: 121.2;kidney: 104.4;liver: 180.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 428.5;Proximal enterocytes: 1858.7;Proximal tubular cells: 1019.7" "Group enriched" "Detected in all" 7 "liver cancer: 62.2;renal cancer: 32.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 32.8;Hep G2: 48.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007040 Enhanced Approved Vesicles,Cytosol NA NA 620000 "Cluster 39: Non-specific - mRNA processing" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Vesicles "HPA007040: AB_1079185" "unprognostic (8.44e-2)" "unprognostic (1.49e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (7.62e-8)" "unprognostic (2.25e-1)" "unprognostic (1.21e-1)" "unprognostic (3.08e-2)" "unprognostic (3.13e-2)" "unprognostic (1.67e-2)" "unprognostic (2.50e-2)" "unprognostic (3.01e-2)" "unprognostic (1.30e-1)" "unprognostic (1.68e-2)" "unprognostic (2.56e-3)" "unprognostic (2.32e-1)" "unprognostic (2.44e-1)" "unprognostic (1.02e-2)" 2.2 4.6 4.2 3.0 4.3 1.7 2.0 7.1 5.9 2.6 1.2 4.2 112.4 3.8 0.6 2.4 4.3 1.3 1.4 4.8 3.9 104.4 180.5 1.6 1.9 5.4 4.0 3.6 9.4 2.6 1.4 0.5 5.5 1.6 1.2 1.5 4.4 1.4 3.8 2.4 121.2 1.9 3.6 2.0 2.9 3.2 3.8 0.7 1.1 2.0 1.2 1.8 2.3 4.7 25.0 18.5 2.8 11.0 2.0 0.5 2.5 1.7 1.1 2.3 1.4 9.0 5.3 3.7 5.8 0.1 2.6 10.7 9.4 3.1 0.8 8.8 17.2 32.8 5.2 48.0 1.1 4.6 3.7 0.1 1.3 2.7 0.2 1.2 2.1 5.1 5.9 6.1 0.2 16.0 5.4 3.6 4.0 22.3 7.2 18.9 1.4 20.9 2.7 3.0 10.2 15.8 3.6 6.2 6.9 1.0 2.7 2.0 1.9 0.7 3.6 1.6 6.5 7.5 14.4 6.3 3.0 10.7 1.8 0.0 5.4 0.3 4.1 3.1 5.5 3.8 6.6 6.0 4.9 3.6 4.7 5.8 0.5 4.9 1.4 6.1 4.7 4.9 4.2 4.3 7.1 5.9 4.8 3.9 5.4 4.0 5.5 3.6 3.8 4.7 6.5 3.2 3.7 1.6 6.8 3.6 2.6 0.8 6.8 3.6 4.7 5.8 1.8 20.0 1.0 40.5 2.1 4.1 1.3 7.4 129.1 3.2 1.2 0.1 0.6 5.5 6.0 15.6 3.4 3.0 3.6 2.4 3.6 0.3 4.5 2.9 9.7 428.5 8.3 6.7 2.7 89.6 4.1 11.9 2.0 6.2 1.8 10.8 8.8 0.0 1.9 9.8 4.1 2.5 2.3 2.1 95.7 1.5 8.0 0.7 1858.7 1019.7 0.0 5.4 0.0 5.0 5.0 1.1 5.8 4.6 6.8 9.4 6.8 0.8 82.6 2.2 KIRREL2 "DKFZp564A1164, FILTRIN, MGC15718, NEPH3, NLG1" ENSG00000126259 "Kirre like nephrin family adhesion molecule 2" Q6UWL6 19 35855861-35867136 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "pancreas: 70.0" "Cell type enriched" "Detected in some" 9 "Bipolar cells: 58.6" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 21.5;HMC-1: 33.0;JURKAT: 19.5;U-937: 7.5" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA071587, HPA074326" Enhanced Supported "Centriolar satellite" "Intracellular and membrane" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" "Centriolar satellite" "HPA071587: AB_2732182, HPA074326: AB_2732251" "unprognostic (1.28e-2)" "unprognostic (1.80e-1)" "unprognostic (3.29e-2)" "unprognostic (3.16e-3)" "unprognostic (2.05e-3)" "unprognostic (2.29e-1)" "unprognostic (2.00e-1)" "unprognostic (1.72e-3)" "unprognostic (3.30e-2)" "unprognostic (5.56e-2)" "unprognostic (4.85e-2)" "unprognostic (2.62e-2)" "unprognostic (2.43e-6)" "unprognostic (1.72e-1)" "unprognostic (4.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.62e-2)" 0.5 0.0 0.5 0.2 1.4 0.1 0.0 0.3 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 1.1 0.0 0.0 0.8 0.4 0.4 0.0 70.0 0.0 0.9 0.1 0.4 0.0 0.1 11.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.6 0.5 0.6 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.7 1.1 0.0 0.0 0.0 1.6 0.1 0.0 0.1 0.0 1.1 0.7 0.0 0.1 0.0 3.6 0.1 2.9 0.0 0.1 21.5 0.1 0.0 0.0 0.3 0.0 0.0 33.0 0.2 0.0 0.0 0.0 0.0 0.0 19.5 0.2 0.3 0.0 0.2 0.6 0.1 0.2 0.1 0.0 5.5 0.0 0.0 0.0 0.0 4.1 1.3 0.0 0.0 0.0 0.1 0.0 5.3 0.0 0.8 1.3 0.3 0.0 0.0 0.0 0.4 0.0 7.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.4 0.3 1.0 0.8 0.1 0.4 0.4 0.4 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.6 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 1.8 0.1 0.2 0.1 0.0 0.0 0.4 6.0 0.1 0.1 0.0 1.0 0.0 0.0 0.0 0.0 2.8 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.0 0.7 5.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.0 0.7 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 KLK7 "PRSS6, SCCE" ENSG00000169035 "Kallikrein related peptidase 7" P49862 19 50976468-50984099 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 94.7;skin 1: 201.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Basal keratinocytes: 5.0;Basal squamous epithelial cells: 4.6;Breast glandular cells: 9.4;Breast myoepithelial cells: 10.4;Squamous epithelial cells: 5.9;Suprabasal keratinocytes: 10.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 139.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 5.0;CAPAN-2: 8.0;HaCaT: 31.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018994, CAB026342, HPA062126" Enhanced Supported "Nuclear membrane,Plasma membrane" "Secreted in other tissues" NA NA 3700000 "Cluster 11: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "Nuclear membrane" "CAB026342: , HPA018994: AB_1852607, HPA062126: AB_2684691" "unprognostic (1.88e-2)" "unprognostic (6.41e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (8.06e-5)" "unprognostic (4.33e-3)" "unprognostic (2.28e-1)" "unprognostic (4.44e-3)" "unprognostic (2.99e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (2.10e-1)" "unprognostic (2.82e-3)" "unprognostic (3.25e-1)" "unprognostic (4.47e-2)" "unprognostic (1.12e-2)" "unprognostic (5.60e-3)" 7.1 0.1 8.4 0.1 9.2 0.3 11.2 0.9 7.4 19.7 1.0 0.1 0.5 0.7 0.2 94.7 16.3 1.3 0.2 6.5 1.4 12.1 0.1 3.1 0.0 4.3 1.4 0.1 0.1 0.3 0.7 0.0 4.9 0.1 0.0 0.1 21.6 0.2 1.0 201.2 0.0 0.2 2.1 0.8 0.3 0.3 7.4 0.9 0.2 0.0 10.9 0.0 30.9 3.0 5.0 0.0 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 1.8 8.0 0.0 1.1 0.0 0.1 31.7 0.0 1.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.3 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 8.4 9.2 0.9 7.4 6.5 1.4 4.3 1.4 4.9 2.1 7.4 3.0 0.0 6.4 1.1 0.0 0.0 5.0 0.1 0.5 4.6 0.0 9.4 10.4 0.2 0.0 2.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 2.6 0.2 0.0 0.0 1.7 0.0 0.0 2.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.2 5.9 10.7 0.0 0.1 0.0 0.1 2.7 KMO ENSG00000117009 "Kynurenine 3-monooxygenase" O15229 1 241532134-241595642 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Pyridine nucleotide biosynthesis" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 31.5;liver: 91.7" "Cell type enhanced" "Detected in many" "B-cells: 33.8;Hepatocytes: 46.9;Langerhans cells: 49.4;Macrophages: 33.0;Proximal tubular cells: 63.2;Syncytiotrophoblasts: 180.1" "Group enriched" "Detected in many" 4 "breast cancer: 1.6;liver cancer: 3.3;renal cancer: 3.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 79 "classical monocyte: 11.0;intermediate monocyte: 32.3;memory B-cell: 36.1;myeloid DC: 11.3;naive B-cell: 42.0;non-classical monocyte: 33.8;plasmacytoid DC: 24.3" "Group enriched" "Detected in many" 97 "B-cells: 42.0;dendritic cells: 24.3;monocytes: 33.8" "Cell line enhanced" "Detected in some" "Daudi: 6.2;RPMI-8226: 9.1;RPTEC TERT1: 21.9;SK-BR-3: 10.9;U-698: 9.4" "Region enriched" "Detected in single" 4 "thalamus: 1.1" "Low region specificity" "Detected in many" "HPA031115, HPA056942" Enhanced NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 57: B-cells - Immune response" "HPA031115: AB_10601924, HPA056942: AB_2683281" "unprognostic (4.27e-2)" "unprognostic (3.35e-2)" "unprognostic (3.95e-2)" "unprognostic (7.48e-3)" "unprognostic (8.37e-3)" "unprognostic (2.63e-1)" "unprognostic (9.79e-2)" "unprognostic (3.65e-1)" "unprognostic (2.42e-1)" "unprognostic (4.75e-3)" "unprognostic (8.07e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (6.49e-8)" "unprognostic (1.60e-2)" "unprognostic (3.65e-2)" "unprognostic (3.36e-2)" "unprognostic (6.81e-2)" 1.4 0.8 0.1 5.1 0.2 1.4 5.3 0.1 1.0 0.6 0.5 0.9 0.6 5.4 0.2 0.2 0.2 1.6 0.4 0.3 0.0 31.5 91.7 5.0 8.8 0.0 0.0 0.2 0.1 0.1 0.2 6.8 0.1 0.3 1.1 0.2 0.3 0.2 0.1 0.2 1.2 0.7 0.0 8.4 1.2 1.3 0.8 1.6 0.2 0.0 11.2 5.6 0.1 0.3 0.2 1.8 0.1 0.0 0.0 0.3 0.3 0.1 0.1 0.2 0.4 0.0 0.2 6.2 0.4 0.0 0.2 2.5 0.0 0.2 0.0 1.1 0.0 0.0 0.1 0.1 0.0 0.6 0.2 0.2 0.7 0.1 0.2 0.5 0.0 0.4 0.1 0.9 0.0 0.2 0.0 2.4 1.0 0.9 0.4 1.6 0.1 9.1 21.9 4.5 0.3 0.1 0.0 10.9 0.1 2.1 4.3 2.1 0.0 0.0 0.1 0.1 1.6 0.4 0.6 9.4 0.2 2.7 1.8 0.1 11.0 0.2 0.0 32.3 0.0 36.1 0.0 0.0 11.3 42.0 0.0 0.1 0.3 0.0 33.8 24.3 0.0 6.1 0.1 0.2 0.1 1.0 0.3 0.0 0.0 0.0 0.1 0.0 0.8 0.3 0.1 0.0 0.5 0.0 33.8 1.0 0.1 13.3 2.2 0.0 1.8 0.8 0.4 2.8 11.1 0.0 0.0 3.6 5.5 0.1 5.9 4.8 4.9 9.5 1.5 0.3 0.0 5.2 6.6 0.2 2.3 0.4 2.0 26.6 0.0 0.1 0.7 46.9 7.0 0.0 30.0 0.0 4.1 22.7 49.4 1.8 0.0 33.0 0.0 0.0 5.5 0.0 1.0 1.0 0.6 1.5 0.0 0.0 11.7 0.2 0.2 63.2 2.3 0.0 0.0 0.1 1.3 1.6 0.3 3.1 1.4 180.1 1.6 0.1 0.0 0.1 KRT85 "Hb-5, KRTHB5" ENSG00000135443 "Keratin 85" P78386 12 52360006-52367481 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 46 "skin 1: 172.7" "Group enriched" "Detected in some" 12 "Early spermatids: 6.2;Late spermatids: 16.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "A549: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA049778 Supported NA NA 110000000 "Cluster 61: Skin - Cornification" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" "HPA049778: AB_2680877" "unprognostic (1.36e-2)" "unprognostic (3.93e-1)" "unprognostic (7.27e-3)" "unprognostic (5.71e-2)" "unprognostic (2.36e-1)" "unprognostic (4.72e-2)" "unprognostic (9.22e-4)" "unprognostic (1.64e-2)" "unprognostic (1.74e-2)" "unprognostic (1.38e-1)" 3.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 172.7 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.4 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 LDHD ENSG00000166816 "Lactate dehydrogenase D" Q86WU2 16 75111860-75116780 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 85.6;liver: 135.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 37.3;Distal enterocytes: 80.2;Distal tubular cells: 37.2;Hepatocytes: 88.6;Proximal tubular cells: 118.1" "Cancer enhanced" "Detected in all" "liver cancer: 32.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 11.1" "Group enriched" "Detected in many" 45 "granulocytes: 11.1;monocytes: 4.8" "Cell line enhanced" "Detected in many" "Hep G2: 11.4;HMC-1: 14.4;T-47d: 29.1;U-266/70: 11.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041766, HPA048639, HPA066148" Enhanced Approved Cytosol No NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA041766: AB_2677660, HPA048639: AB_2680473, HPA066148: AB_2685626" "unprognostic (8.75e-2)" "unprognostic (3.68e-3)" "unprognostic (1.27e-1)" "unprognostic (5.28e-2)" "unprognostic (1.57e-1)" "unprognostic (1.53e-1)" "prognostic favorable (5.61e-4)" "unprognostic (2.49e-3)" "unprognostic (1.91e-1)" "unprognostic (2.72e-1)" "unprognostic (3.74e-1)" "unprognostic (4.01e-1)" "prognostic favorable (2.95e-14)" "unprognostic (4.10e-3)" "unprognostic (4.49e-2)" "unprognostic (7.00e-2)" "unprognostic (2.20e-1)" 24.9 14.4 17.7 2.1 19.7 0.7 11.7 20.5 22.6 5.4 34.1 27.2 8.8 3.5 1.1 10.8 5.5 3.0 85.6 16.1 18.9 36.1 135.5 4.9 0.8 20.8 20.2 16.4 18.7 17.0 11.8 0.7 22.4 8.1 9.7 1.3 21.3 3.2 68.7 5.8 5.7 1.2 17.0 1.1 23.1 1.7 19.3 0.5 10.6 52.7 0.6 2.6 3.7 17.5 0.7 2.1 0.0 0.2 1.6 1.4 6.1 0.2 0.1 0.2 0.2 2.8 2.6 0.1 2.1 0.9 1.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.8 11.4 2.6 0.0 14.4 2.0 0.3 0.0 0.0 0.6 0.1 0.4 0.7 2.5 0.0 5.3 0.1 0.8 1.4 2.7 1.3 0.0 0.0 7.8 1.4 0.1 0.0 0.0 0.2 5.2 0.3 0.7 29.1 3.3 0.0 0.0 0.2 0.0 0.0 11.5 0.6 0.0 1.9 0.1 0.0 11.1 2.2 0.6 0.0 3.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.8 17.7 19.7 20.5 22.6 16.1 18.9 20.8 20.2 22.4 17.0 19.3 17.5 1.6 0.0 6.7 7.8 1.0 0.6 1.8 2.2 0.6 0.5 6.5 2.4 37.3 11.5 2.3 11.0 0.0 2.1 0.1 80.2 37.2 2.3 0.4 2.2 0.3 1.7 3.0 2.7 1.0 6.2 1.2 2.3 32.6 3.8 10.2 2.1 4.2 88.6 7.2 1.7 1.4 11.0 0.0 6.0 1.0 0.6 0.0 3.0 5.4 1.9 2.0 12.0 0.0 1.0 3.2 3.0 28.3 0.0 0.8 2.1 2.4 118.1 2.0 1.4 0.0 4.1 1.3 0.0 0.7 3.6 0.3 3.1 1.0 1.8 15.7 1.5 LGALS2 HL14 ENSG00000100079 "Galectin 2" P05162 22 37570248-37582616 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 335.5;intestine: 198.0;kidney: 153.0;pancreas: 211.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 779.2;Distal enterocytes: 695.4;Langerhans cells: 982.8;Proximal enterocytes: 2724.7;Proximal tubular cells: 1764.8;Undifferentiated cells: 749.3" "Cancer enhanced" "Detected in all" "renal cancer: 54.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 27 "classical monocyte: 1464.7;intermediate monocyte: 553.8;myeloid DC: 1207.2" "Group enriched" "Detected in all" 50 "dendritic cells: 1207.2;monocytes: 1464.7" "Group enriched" "Detected in many" 4 "CACO-2: 109.4;Hep G2: 62.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA003536, CAB025198" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria Nucleoplasm "CAB025198: , HPA003536: AB_1078936" "unprognostic (1.37e-3)" "unprognostic (4.11e-3)" "unprognostic (1.32e-3)" "unprognostic (4.32e-2)" "unprognostic (1.74e-1)" "unprognostic (2.91e-3)" "unprognostic (3.19e-1)" "unprognostic (9.92e-2)" "unprognostic (8.07e-2)" "unprognostic (2.58e-1)" "unprognostic (6.15e-2)" "unprognostic (5.19e-1)" "unprognostic (2.33e-3)" "unprognostic (1.80e-1)" "unprognostic (6.70e-2)" "unprognostic (5.01e-3)" "unprognostic (1.21e-1)" 7.5 1.4 0.6 23.5 1.4 19.2 5.4 0.2 1.1 1.8 0.2 55.0 41.2 3.6 1.0 5.2 4.4 335.5 1.6 0.5 1.0 153.0 5.0 8.6 60.7 1.6 1.2 0.9 211.5 0.2 0.1 1.7 1.4 2.2 81.1 0.1 2.1 0.7 1.9 9.9 198.0 5.2 0.4 59.2 10.7 0.6 1.1 41.3 1.0 0.7 64.0 8.2 0.5 3.4 2.8 1.5 0.9 1.0 0.0 0.0 1.1 1.7 0.0 0.0 0.0 109.4 0.1 0.4 0.3 0.0 0.3 1.7 0.0 0.0 0.0 0.2 1.1 0.0 0.0 62.5 0.3 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.0 0.5 0.0 0.0 2.8 0.0 1.0 0.4 21.2 0.3 0.0 0.9 1.3 0.0 0.0 0.0 0.3 1.7 1.9 2.4 0.5 1.6 1.7 6.4 2.0 1.0 4.3 0.8 0.0 0.2 0.3 2.7 0.2 1.3 7.7 1464.7 8.7 1.8 553.8 3.3 9.9 1.8 2.1 1207.2 2.3 2.3 1.9 26.8 2.3 39.7 9.6 3.0 981.5 0.6 1.4 0.2 1.1 0.5 1.0 1.6 1.2 1.4 0.4 1.1 3.4 1.6 6.4 3.9 0.0 16.4 17.1 0.1 0.5 0.0 0.0 13.2 7.5 0.3 779.2 1.4 29.5 0.0 0.2 7.0 695.4 127.2 26.3 0.1 0.1 0.3 2.3 73.7 4.8 0.1 206.7 0.3 3.2 5.6 0.2 2.5 0.0 0.7 1.9 26.4 0.0 0.1 413.0 0.0 100.8 982.8 0.3 0.6 150.8 24.9 0.0 164.8 0.0 4.1 0.0 0.1 291.6 331.6 0.0 0.9 0.3 2724.7 1764.8 2.1 0.0 0.0 0.3 2.3 0.0 0.4 0.1 12.4 0.3 8.6 0.0 749.3 0.3 LGSN "GLULD1, LGS" ENSG00000146166 "Lengsin, lens protein with glutamine synthetase domain" Q5TDP6 6 63275951-63319983 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 2.0;liver: 3.8;placenta: 1.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 3.5;Inhibitory neurons: 3.7;Late spermatids: 4.4;Oligodendrocytes: 5.9;Proximal tubular cells: 5.6;Respiratory ciliated cells: 3.0" "Cancer enriched" "Detected in some" 4 "lung cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 6.2;BEWO: 3.3;CACO-2: 1.6;HeLa: 1.8;Karpas-707: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA030957, HPA039983" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Vesicles" "HPA030957: AB_10670149, HPA039983: AB_2676784" "unprognostic (1.94e-1)" "unprognostic (1.72e-1)" "unprognostic (1.12e-1)" "unprognostic (9.03e-2)" "unprognostic (2.81e-1)" "unprognostic (1.01e-1)" "unprognostic (5.05e-4)" "unprognostic (1.26e-1)" "unprognostic (1.74e-1)" "unprognostic (1.08e-1)" "unprognostic (2.13e-1)" "unprognostic (2.53e-2)" "unprognostic (4.51e-3)" "unprognostic (1.64e-3)" "unprognostic (1.31e-1)" "unprognostic (2.19e-1)" 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.4 0.2 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 2.0 3.8 0.2 0.0 0.3 0.1 0.0 0.3 0.0 0.0 1.1 0.2 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 6.2 0.0 0.0 0.0 0.0 3.3 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.4 0.2 0.1 0.1 0.3 0.1 0.2 0.1 0.1 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.0 0.0 0.0 2.2 0.0 1.1 1.9 0.1 1.2 2.0 0.0 0.1 0.0 0.0 3.5 0.2 0.5 0.1 0.0 0.0 0.0 0.3 0.0 1.1 0.3 0.0 3.7 0.7 0.0 0.3 0.0 4.4 0.3 0.1 0.0 1.9 0.0 0.0 0.0 1.5 5.9 0.0 0.3 0.0 0.1 0.2 0.1 5.6 3.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 1.4 0.1 0.1 0.8 0.2 LIME1 "dJ583P15.4, FLJ20406, LIME" ENSG00000203896 "Lck interacting transmembrane adaptor 1" Q9H400 20 63736283-63739103 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 242.8" "Cell type enriched" "Detected in some" 5 "Plasma cells: 210.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 314.8;MAIT T-cell: 285.2;memory CD4 T-cell: 437.6;memory CD8 T-cell: 412.5;naive CD4 T-cell: 289.4;naive CD8 T-cell: 319.4;plasmacytoid DC: 749.3;T-reg: 689.4" "Group enriched" "Detected in all" 8 "dendritic cells: 749.3;T-cells: 689.4" "Cell line enhanced" "Detected in many" "Karpas-707: 33.9;MOLT-4: 37.9;RPMI-8226: 144.4;U-266/70: 71.1" "Low region specificity" "Detected in many" CAB015363 Approved "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 58: T-cells - T-cell receptor" "CAB015363: AB_629890" "unprognostic (1.16e-1)" "unprognostic (2.35e-1)" "unprognostic (5.95e-3)" "unprognostic (3.01e-1)" "unprognostic (1.34e-1)" "unprognostic (3.85e-3)" "unprognostic (3.06e-2)" "unprognostic (1.46e-1)" "unprognostic (1.36e-1)" "unprognostic (1.94e-1)" "unprognostic (1.05e-3)" "unprognostic (1.51e-3)" "prognostic unfavorable (5.04e-5)" "unprognostic (2.39e-2)" "unprognostic (4.25e-2)" "unprognostic (1.67e-1)" "prognostic favorable (6.92e-6)" 8.9 5.6 2.2 5.6 5.6 4.7 5.8 2.6 7.0 8.8 0.8 11.8 2.2 5.9 0.0 11.2 6.8 0.0 5.1 2.9 1.4 54.5 242.8 9.0 10.7 2.8 1.8 9.6 5.1 0.1 11.3 0.1 2.5 13.4 0.3 0.0 12.5 0.4 3.9 13.2 18.7 0.0 1.0 43.2 18.3 5.9 3.5 6.1 11.2 0.0 1.2 7.6 9.2 4.8 2.0 0.6 0.1 0.4 0.0 0.0 4.9 2.6 0.2 0.3 0.0 1.1 2.1 5.7 3.8 0.1 0.0 5.1 0.0 0.3 0.3 2.5 4.8 1.1 2.3 25.4 0.0 1.5 2.1 0.2 0.7 0.0 0.0 0.0 0.0 16.4 2.1 33.9 0.0 1.1 37.9 10.7 2.0 1.3 6.6 25.9 0.8 144.4 0.4 0.3 2.0 2.9 1.3 1.3 2.8 0.0 1.1 0.8 0.5 1.8 2.8 1.9 1.5 71.1 3.0 12.7 1.5 1.1 0.7 1.9 1.5 1.8 314.8 1.0 285.2 76.4 437.6 412.5 2.4 37.2 289.4 319.4 10.6 85.5 1.7 749.3 689.4 193.8 2.2 5.6 2.6 7.0 2.9 1.4 2.8 1.8 2.5 1.0 3.5 4.8 0.0 0.0 0.0 21.5 7.2 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.8 7.7 0.0 0.0 0.3 22.4 0.0 0.0 0.0 0.4 3.1 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 5.6 0.1 0.0 0.0 9.0 9.6 0.0 0.0 0.0 210.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 5.8 0.1 0.0 36.7 0.0 0.1 0.0 LMX1B NPS1 ENSG00000136944 "LIM homeobox transcription factor 1 beta" O60663 9 126613928-126701032 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.2;salivary gland: 18.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 8.3;Breast myoepithelial cells: 7.2;Cardiomyocytes: 1.9;Early spermatids: 1.6;Spermatogonia: 2.1" "Cancer enriched" "Detected in some" 14 "breast cancer: 12.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 3.5;HEK 293: 3.6;MCF7: 11.9;OE19: 10.4;T-47d: 8.1" "Region enhanced" "Detected in some" "pons and medulla: 2.3" "Region enhanced" "Detected in many" "midbrain: 5.0" "HPA073716, HPA075656" Approved Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "HPA073716: AB_2686630, HPA075656: " "unprognostic (4.17e-1)" "unprognostic (4.72e-2)" "unprognostic (2.81e-2)" "unprognostic (2.53e-4)" "unprognostic (1.73e-1)" "unprognostic (1.50e-4)" "unprognostic (1.86e-1)" "unprognostic (2.20e-2)" "unprognostic (3.41e-1)" "unprognostic (2.26e-1)" "unprognostic (1.34e-2)" "unprognostic (3.51e-3)" "unprognostic (1.63e-5)" "unprognostic (1.69e-1)" "unprognostic (1.23e-1)" "unprognostic (1.56e-6)" "unprognostic (1.13e-2)" 0.6 0.0 0.1 0.0 0.1 0.1 4.1 0.1 5.6 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.0 1.0 3.6 0.0 0.1 0.0 3.8 9.2 0.0 0.2 1.1 0.2 0.0 3.3 0.0 0.0 0.0 18.5 0.0 0.1 2.1 0.1 0.0 6.8 0.0 0.1 1.4 2.6 0.0 0.4 0.0 0.0 0.0 0.0 0.5 1.2 0.6 0.3 2.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.3 0.0 2.5 0.6 3.5 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.5 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 11.9 0.0 0.0 0.0 10.4 0.0 0.0 2.4 0.0 0.0 0.1 0.0 1.1 0.3 0.0 0.2 0.1 8.1 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 5.6 1.0 1.0 3.8 9.2 3.3 6.8 2.6 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 8.3 7.2 1.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.8 1.6 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 LPA "LP, Lp(a)" ENSG00000198670 Lipoprotein(a) P08519 6 160531482-160664275 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid transport, Transport" "Hydrolase, Protease, Serine protease" Atherosclerosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "liver: 76.7" "Cell type enriched" "Detected in some" 28 "Hepatocytes: 80.7" "Cancer enriched" "Detected in single" 38 "liver cancer: 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "RT4: 1.0" "CAB016072, HPA060604" Supported "Secreted to blood" NA NA 78800000000 1800000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 15: Hepatocytes - Hemostasis" "CAB016072: AB_2135240, HPA060604: AB_2684330" "unprognostic (2.16e-1)" "unprognostic (5.10e-1)" "unprognostic (7.75e-3)" "unprognostic (6.70e-2)" "unprognostic (1.60e-1)" "unprognostic (4.17e-3)" "unprognostic (1.59e-1)" "unprognostic (6.38e-3)" "unprognostic (3.63e-2)" "unprognostic (3.18e-1)" "unprognostic (7.45e-3)" "unprognostic (2.56e-1)" "unprognostic (1.80e-1)" "unprognostic (1.34e-1)" "unprognostic (3.72e-2)" 0.0 0.1 2.0 0.0 1.2 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.2 0.4 0.1 0.8 0.0 0.0 0.8 6.3 0.5 76.7 0.1 0.0 1.8 1.9 0.2 0.6 0.0 0.0 0.0 1.3 0.6 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 4.2 1.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.2 0.0 1.1 0.8 6.3 1.8 1.9 1.3 0.2 4.2 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 2.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.1 0.0 0.2 0.0 2.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 80.7 0.0 0.0 1.3 0.0 0.0 2.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 LRP2 "DBS, gp330" ENSG00000081479 "LDL receptor related protein 2" P98164 2 169127109-169362534 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Endocytosis, Hearing, Neurogenesis, Transport" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 70.5;kidney: 34.8;parathyroid gland: 44.7;retina: 29.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 87.6;Cytotrophoblasts: 63.2;Oligodendrocytes: 300.1;Proximal tubular cells: 283.9" "Cancer enhanced" "Detected in many" "renal cancer: 29.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "AF22: 39.4;CACO-2: 64.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA005980, HPA064792" Enhanced Approved Vesicles,Mitochondria No NA 74000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Mitochondria" "HPA005980: AB_1079278, HPA064792: AB_2685353" "unprognostic (1.87e-1)" "unprognostic (1.04e-3)" "unprognostic (1.32e-3)" "unprognostic (3.65e-3)" "unprognostic (3.18e-2)" "unprognostic (1.60e-2)" "unprognostic (1.64e-3)" "unprognostic (2.99e-1)" "unprognostic (1.94e-1)" "unprognostic (1.39e-1)" "unprognostic (4.09e-2)" "unprognostic (4.38e-1)" "prognostic favorable (3.43e-5)" "unprognostic (1.37e-1)" "unprognostic (4.21e-1)" "unprognostic (2.44e-2)" "unprognostic (1.62e-2)" 1.5 0.0 5.5 0.0 23.4 0.1 9.6 18.9 13.5 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.2 7.5 14.6 34.8 0.3 1.2 0.0 30.5 17.5 0.0 0.0 44.7 0.1 7.5 31.9 0.0 0.0 29.3 0.9 0.0 0.1 0.1 0.0 0.0 14.5 0.0 0.0 0.2 18.7 0.0 17.3 0.0 0.0 0.0 0.0 70.5 0.0 0.0 39.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 64.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 4.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.2 0.0 0.5 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 23.4 18.9 13.5 7.5 14.6 30.5 17.5 31.9 14.5 18.7 70.5 0.2 6.4 43.7 1.0 3.0 0.3 0.2 0.0 0.0 2.8 22.9 15.1 2.1 2.8 2.5 3.7 87.6 63.2 0.2 0.0 17.6 0.0 3.1 0.1 0.1 0.5 0.0 0.0 1.8 0.0 2.2 1.8 0.0 0.1 2.5 0.0 0.0 0.8 5.1 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.0 2.5 0.0 1.9 0.0 33.1 0.0 1.5 300.1 0.0 0.0 0.0 0.0 0.0 0.0 283.9 2.2 19.5 0.0 0.0 0.3 0.1 0.8 0.0 0.0 23.1 1.7 0.0 0.0 0.2 LRRC25 "FLJ38116, MAPA" ENSG00000175489 "Leucine rich repeat containing 25" Q8N386 19 18391137-18397622 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 32.4;lymphoid tissue: 61.2" "Group enriched" "Detected in some" 6 "Hofbauer cells: 47.0;Kupffer cells: 123.6;Macrophages: 90.0;monocytes: 74.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 320.6;eosinophil: 356.2;intermediate monocyte: 512.1;myeloid DC: 229.3;neutrophil: 573.0;non-classical monocyte: 706.7" "Group enriched" "Detected in all" 60 "dendritic cells: 229.3;granulocytes: 573.0;monocytes: 706.7" "Cell line enhanced" "Detected in some" "Hep G2: 1.0;HMC-1: 1.8;THP-1: 1.7;U-937: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029459 Approved Approved "Endoplasmic reticulum,Microtubules,Cytosol" NA NA 630000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Endoplasmic reticulum, Microtubules, Cytosol" "HPA029459: AB_10610005" "unprognostic (2.72e-2)" "unprognostic (6.08e-2)" "unprognostic (1.76e-2)" "unprognostic (2.07e-1)" "unprognostic (3.77e-2)" "unprognostic (9.15e-2)" "unprognostic (5.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-2)" "unprognostic (4.63e-2)" "unprognostic (2.02e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-3)" "unprognostic (5.77e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (1.74e-1)" "unprognostic (1.14e-1)" 9.4 9.4 2.4 21.8 2.5 32.4 3.1 3.3 2.9 1.8 3.2 3.3 3.7 1.6 0.7 2.3 3.9 5.3 2.5 2.3 3.1 2.4 5.9 11.5 9.9 4.6 4.0 1.5 2.0 0.7 1.2 5.4 4.2 2.0 2.8 0.3 2.6 1.2 3.7 1.0 4.8 6.7 2.8 61.2 2.3 1.2 5.4 3.0 1.2 8.7 4.0 7.0 1.3 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.3 1.0 0.8 0.4 1.8 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.4 0.2 0.1 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.7 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.2 1.5 0.1 55.4 320.6 356.2 0.9 512.1 1.9 7.3 0.6 0.7 229.3 8.4 0.5 0.6 573.0 4.6 706.7 32.1 1.3 229.2 2.4 2.5 3.3 2.9 2.3 3.1 4.6 4.0 4.2 2.8 5.4 4.7 0.7 0.0 1.3 0.0 5.0 0.0 0.1 0.1 0.0 0.1 0.3 1.0 0.3 0.0 0.7 0.0 0.0 0.1 2.9 0.1 5.9 0.1 1.9 0.2 0.1 0.9 0.0 2.1 0.1 0.0 0.4 0.5 0.0 0.4 10.2 0.0 1.8 0.5 47.0 0.0 0.1 0.0 0.0 123.6 12.5 0.5 0.0 90.0 1.8 1.0 74.9 0.0 6.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 2.4 0.2 0.0 0.2 0.0 0.1 0.4 1.1 0.2 0.1 0.1 MACROD1 LRP16 ENSG00000133315 "Mono-ADP ribosylhydrolase 1" Q9BQ69 11 63998558-64166113 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 290.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 137.0;Proximal tubular cells: 333.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 73.8;RPMI-8226: 145.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041031, HPA071075" Uncertain Supported Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 59: Non-specific - Translation" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA041031: AB_10794435, HPA071075: AB_2686341" "unprognostic (1.19e-2)" "unprognostic (2.15e-1)" "unprognostic (1.38e-1)" "unprognostic (3.14e-2)" "unprognostic (3.88e-2)" "unprognostic (6.03e-2)" "unprognostic (1.95e-2)" "unprognostic (2.82e-1)" "unprognostic (2.44e-2)" "unprognostic (1.34e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.15e-1)" "prognostic favorable (4.68e-6)" "unprognostic (2.45e-2)" "unprognostic (9.92e-2)" "unprognostic (2.36e-1)" "unprognostic (2.86e-2)" 14.9 14.1 6.4 1.3 5.9 2.8 17.3 6.8 12.7 15.6 5.9 21.3 5.7 13.8 0.9 18.6 15.3 2.2 111.6 6.4 8.2 55.1 50.2 10.4 1.1 8.6 7.9 21.6 49.5 4.1 11.8 1.6 8.8 19.6 1.4 1.2 30.1 5.5 290.1 26.0 10.7 1.1 6.6 6.5 27.2 4.7 9.1 1.0 32.0 58.9 0.5 17.4 16.8 7.4 12.7 5.7 1.9 10.2 1.7 1.0 10.9 7.5 3.2 5.3 5.1 5.3 33.2 44.9 25.4 0.6 2.6 29.8 1.9 0.1 0.6 3.6 21.9 16.8 23.3 29.7 6.1 13.8 1.8 2.5 3.4 0.6 1.7 4.5 1.8 14.7 15.2 8.5 1.1 73.8 20.1 45.1 5.5 4.3 24.4 18.7 11.5 145.4 1.8 0.7 15.7 31.2 5.7 40.3 41.4 0.2 29.8 1.0 2.9 4.9 7.4 7.0 0.8 17.8 3.1 7.4 3.4 13.4 4.6 0.0 0.0 0.0 0.4 0.2 0.4 0.1 0.4 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 6.4 5.9 6.8 12.7 6.4 8.2 8.6 7.9 8.8 6.6 9.1 7.4 19.4 0.0 4.6 6.8 7.1 28.0 39.8 7.5 57.5 15.1 46.2 45.0 32.5 30.0 8.6 42.3 0.0 35.6 1.3 34.6 137.0 20.8 7.1 19.0 13.3 11.9 22.9 8.0 7.1 40.4 16.1 15.9 20.9 22.7 0.0 41.6 9.7 45.3 11.7 11.8 12.4 55.2 8.2 6.9 5.1 26.8 24.8 7.2 39.2 4.7 2.4 16.9 1.0 13.6 6.9 19.2 35.2 14.3 12.9 37.6 23.0 333.4 3.1 20.6 19.7 55.7 19.1 8.2 32.5 46.3 37.1 23.9 6.1 18.8 67.9 49.8 MAF c-MAF ENSG00000178573 "MAF bZIP transcription factor" O75444 16 79585843-79600737 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, Mental retardation, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 407.6;Hofbauer cells: 273.6;Inhibitory neurons: 378.7;Kupffer cells: 394.7;Proximal enterocytes: 288.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 38.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 38.1" "Group enriched" "Detected in some" 13 "Karpas-707: 207.0;RPMI-8226: 355.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010296, HPA028289" Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB010296: AB_638562, HPA028289: AB_10602024" "unprognostic (6.76e-2)" "unprognostic (1.74e-2)" "unprognostic (6.45e-2)" "unprognostic (7.65e-2)" "unprognostic (7.89e-3)" "unprognostic (1.07e-2)" "unprognostic (1.63e-2)" "unprognostic (2.33e-1)" "unprognostic (8.76e-2)" "unprognostic (3.16e-2)" "unprognostic (9.46e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (3.74e-4)" "unprognostic (4.54e-2)" "unprognostic (7.83e-2)" "unprognostic (1.09e-2)" "unprognostic (4.56e-3)" 27.8 15.4 14.6 20.7 14.5 4.0 17.3 10.3 13.5 35.0 14.2 11.4 70.3 23.5 6.0 22.6 20.1 16.7 6.8 13.7 13.0 48.2 25.7 18.8 30.9 19.0 22.6 39.2 3.2 50.8 5.3 36.1 17.6 18.4 10.7 4.7 11.8 15.4 49.6 57.8 83.0 17.8 18.7 26.0 13.0 10.0 28.7 17.9 23.1 19.8 23.9 17.7 30.5 29.8 0.0 0.0 22.4 0.0 0.8 0.0 0.5 2.2 0.1 0.0 0.0 0.3 0.0 0.1 0.0 1.2 0.0 0.8 0.7 0.4 0.0 7.2 8.3 0.0 0.0 0.2 1.0 0.1 14.3 0.1 6.4 0.0 0.2 0.0 0.0 0.3 2.4 207.0 1.5 0.1 0.2 0.4 13.5 0.0 0.0 0.1 6.2 355.1 0.0 1.9 0.5 0.3 0.9 0.2 0.6 8.7 0.2 0.0 4.5 0.0 6.9 0.5 0.9 0.0 0.0 0.0 0.9 0.0 1.4 38.1 0.3 0.0 1.1 1.1 8.6 0.0 3.2 2.7 0.1 0.0 0.2 0.5 0.0 0.9 0.3 0.0 4.7 0.6 14.6 14.5 10.3 13.5 13.7 13.0 19.0 22.6 17.6 18.7 28.7 29.8 40.2 9.6 14.6 24.8 10.4 88.3 3.7 30.1 51.2 9.7 8.5 33.1 8.2 57.2 7.7 3.7 0.0 1.7 71.5 18.2 11.7 1.7 1.1 8.1 114.1 42.7 3.0 8.4 5.1 0.8 3.0 73.0 12.8 6.6 22.1 73.0 407.6 63.7 273.6 0.0 378.7 8.9 16.2 394.7 57.9 9.0 149.8 127.2 44.4 122.7 2.7 78.1 40.2 67.3 20.0 4.0 9.9 115.1 48.1 33.9 288.9 146.6 3.0 2.7 13.1 42.7 40.0 1.1 2.0 107.4 141.2 4.2 122.2 28.0 10.1 5.4 MAJIN C11orf85 ENSG00000168070 "Membrane anchored junction protein" Q3KP22 11 64937517-64972108 "Predicted intracellular proteins" Meiosis DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 22.5" "Group enriched" "Detected in some" 8 "Distal tubular cells: 3.9;Proximal tubular cells: 9.5" "Cancer enhanced" "Detected in some" "cervical cancer: 1.0" "Region enriched" "Detected in single" 4 "cerebellum: 2.6" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.3" "Lineage enriched" "Detected in single" 5 "B-cells: 1.3" "Group enriched" "Detected in some" 10 "CAPAN-2: 7.5;SiHa: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (3.37e-1)" "unprognostic (6.43e-3)" "unprognostic (3.69e-2)" "unprognostic (7.05e-2)" "unprognostic (9.64e-3)" "unprognostic (2.92e-2)" "unprognostic (4.46e-2)" "unprognostic (1.06e-1)" "unprognostic (9.11e-2)" "unprognostic (4.11e-2)" "unprognostic (1.61e-2)" "unprognostic (2.58e-1)" "unprognostic (1.48e-2)" "unprognostic (2.43e-1)" "unprognostic (2.79e-1)" "unprognostic (4.18e-3)" "unprognostic (1.76e-2)" 0.0 0.2 0.2 0.2 0.6 0.1 0.2 2.6 0.6 0.1 0.0 0.1 0.0 0.0 2.0 0.1 1.1 2.9 0.0 0.1 0.1 1.4 1.2 0.2 1.4 0.5 0.2 0.0 0.3 0.0 0.0 0.1 0.3 0.3 0.2 0.2 0.1 0.6 0.0 1.2 0.4 0.0 0.2 0.6 0.2 22.5 0.1 0.1 0.9 0.0 1.3 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 2.6 0.6 0.1 0.1 0.5 0.2 0.3 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.3 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 MANSC4 ENSG00000205693 "MANSC domain containing 4" A6NHS7 12 27762427-27780236 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "testis: 1.5" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 2.1;Oligodendrocyte precursor cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA039454, HPA039682" Uncertain NA NA "Cluster 34: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA039454: AB_2676515, HPA039682: AB_10805483" "unprognostic (1.13e-1)" "unprognostic (4.74e-2)" "unprognostic (2.34e-2)" "unprognostic (2.75e-2)" "unprognostic (6.07e-2)" "unprognostic (1.09e-1)" "unprognostic (1.18e-1)" "unprognostic (2.25e-4)" "unprognostic (1.96e-1)" "unprognostic (2.49e-2)" "unprognostic (2.87e-3)" "unprognostic (2.50e-3)" "unprognostic (7.15e-3)" "unprognostic (2.34e-1)" "unprognostic (1.00e-2)" "unprognostic (1.21e-1)" "unprognostic (2.10e-2)" 0.1 0.0 0.2 0.1 0.1 0.2 0.1 0.6 0.3 0.1 0.1 0.1 0.1 0.2 0.2 0.0 0.1 0.0 0.0 0.2 0.2 0.4 0.0 0.2 0.5 0.3 0.1 0.2 0.2 0.0 0.7 0.5 0.1 0.1 0.0 0.5 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.1 1.5 0.3 0.1 0.1 0.1 0.3 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.6 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.2 0.1 0.5 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.6 0.3 0.2 0.2 0.3 0.1 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.7 0.0 0.2 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 MAP7D2 FLJ14503 ENSG00000184368 "MAP7 domain containing 2" Q96T17 X 20006713-20116907 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 66.6;epididymis: 36.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 93.0;Excitatory neurons: 45.5;Inhibitory neurons: 55.2;Spermatocytes: 57.8;Spermatogonia: 134.9" "Cancer enhanced" "Detected in many" "testis cancer: 7.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 3.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 3.0" "Cell line enhanced" "Detected in some" "A549: 13.3;CACO-2: 19.3;HEK 293: 25.0;HeLa: 21.4;Hep G2: 11.4;SCLC-21H: 29.1;SiHa: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051508, HPA059537" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm Cytosol "HPA051508: AB_2681513, HPA059537: AB_2684054" "unprognostic (1.51e-1)" "unprognostic (9.19e-2)" "unprognostic (3.76e-1)" "unprognostic (1.45e-5)" "unprognostic (5.65e-2)" "unprognostic (9.77e-3)" "unprognostic (1.50e-1)" "unprognostic (1.50e-1)" "unprognostic (5.95e-2)" "unprognostic (7.77e-3)" "unprognostic (3.58e-4)" "unprognostic (2.21e-2)" "prognostic unfavorable (7.27e-5)" "unprognostic (9.12e-3)" "unprognostic (3.60e-2)" "unprognostic (2.54e-3)" "unprognostic (3.19e-1)" 0.2 2.8 11.6 0.3 15.3 0.7 0.4 12.5 66.6 0.3 0.0 0.7 0.7 0.6 36.4 0.2 2.3 0.5 0.4 13.9 16.3 3.5 0.1 0.2 0.2 35.8 7.0 0.3 1.1 0.0 3.9 7.6 28.9 0.8 0.8 14.6 0.2 2.0 0.5 0.9 1.2 0.4 3.0 0.1 8.7 9.6 17.1 2.3 0.1 0.1 0.3 0.1 0.3 20.0 0.0 13.3 1.1 0.1 0.1 0.3 0.0 1.4 0.0 0.2 0.1 19.3 0.5 2.3 2.0 0.0 0.2 0.0 0.0 0.0 0.1 1.0 25.0 0.0 21.4 11.4 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.2 5.0 1.0 0.0 0.3 0.0 0.0 1.5 0.0 29.1 5.0 12.8 4.4 0.0 2.8 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.5 1.4 0.1 1.4 3.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 11.6 15.3 12.5 66.6 13.9 16.3 35.8 7.0 28.9 3.0 17.1 20.0 0.2 3.2 0.0 4.6 0.6 1.8 0.3 7.2 0.6 29.1 0.9 1.1 1.2 0.0 2.5 0.0 2.1 93.0 0.8 2.2 3.9 1.3 16.4 0.6 0.2 0.7 9.6 0.0 45.5 0.9 9.2 1.1 28.1 0.7 0.0 12.3 0.0 0.2 6.1 18.5 55.2 0.6 2.0 0.0 0.7 17.8 0.6 0.7 0.0 6.5 0.0 2.8 0.0 11.1 3.6 0.8 4.8 1.9 0.9 1.0 3.5 18.8 6.9 8.1 0.0 0.6 0.8 57.8 134.9 0.9 1.6 30.6 0.4 0.9 1.3 0.5 MAPT "DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, PPP1R103, tau" ENSG00000186868 "Microtubule associated protein tau" P10636 17 45894527-46028334 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Alzheimer disease, Disease variant, FDA approved drug targets, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 67.7;skeletal muscle: 79.0" "Cell type enhanced" "Detected in many" "Astrocytes: 142.4;Bipolar cells: 314.4;Early spermatids: 199.9;Excitatory neurons: 189.2;Horizontal cells: 361.7;Inhibitory neurons: 153.7;Late spermatids: 416.6;Muller glia cells: 145.7;Oligodendrocytes: 163.8" "Cancer enhanced" "Detected in many" "breast cancer: 9.5;glioma: 13.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.7" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 5 "HDLM-2: 69.0;SCLC-21H: 21.1;T-47d: 34.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000151, HPA048895, HPA069524, HPA069570, CAB072344" Enhanced Supported "Nuclear speckles,Plasma membrane" "Secreted to blood" NA NA 7100 "Cluster 35: T-regs - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Nuclear speckles" "CAB000151: , CAB072344: , HPA048895: AB_2680550, HPA069524: AB_2686145, HPA069570: AB_2686155" "unprognostic (1.78e-3)" "unprognostic (7.51e-2)" "unprognostic (3.71e-2)" "unprognostic (8.40e-5)" "unprognostic (1.40e-1)" "unprognostic (1.31e-2)" "unprognostic (4.06e-5)" "unprognostic (6.04e-2)" "unprognostic (2.19e-2)" "unprognostic (3.49e-2)" "unprognostic (3.88e-3)" "unprognostic (2.65e-1)" "unprognostic (1.72e-3)" "unprognostic (6.53e-2)" "unprognostic (3.43e-1)" "unprognostic (1.85e-2)" "unprognostic (5.47e-2)" 4.7 4.3 26.2 0.3 27.1 0.0 9.1 8.3 67.7 2.4 0.0 8.4 0.5 1.0 0.2 8.4 1.0 0.8 9.4 30.0 20.4 14.7 0.6 0.8 0.3 11.6 11.4 0.6 1.5 2.9 29.5 3.4 22.4 5.4 0.3 17.6 8.5 3.4 79.0 6.3 1.8 0.3 2.7 0.4 1.7 20.3 14.8 0.4 0.9 27.4 0.2 10.2 2.3 19.7 2.9 0.5 0.3 6.4 0.3 0.9 1.8 0.1 0.3 0.1 0.0 0.2 0.0 0.0 0.6 0.4 0.5 0.1 2.3 0.3 0.0 69.0 3.4 0.0 0.3 4.2 0.0 0.1 0.1 0.0 0.5 0.1 0.3 0.1 0.0 4.4 0.7 3.6 0.0 7.7 1.0 0.2 0.2 0.7 2.0 0.0 4.0 8.5 0.0 9.1 21.1 9.1 2.5 0.0 1.8 1.0 34.7 0.1 0.1 0.3 0.8 1.7 0.3 0.9 0.3 0.0 0.6 2.0 0.5 0.1 0.0 0.0 0.2 0.7 0.2 0.0 0.1 0.5 0.0 0.0 0.2 0.3 0.2 0.1 1.7 0.0 0.7 0.0 26.2 27.1 8.3 67.7 30.0 20.4 11.6 11.4 22.4 2.7 14.8 19.7 1.9 0.0 9.8 142.4 1.0 1.0 1.4 0.2 1.2 314.4 26.7 21.2 35.2 0.0 0.1 1.8 64.6 0.2 0.4 0.1 7.9 0.5 199.9 0.4 1.7 1.8 0.0 0.0 189.2 0.4 9.1 3.7 0.5 1.3 4.5 1.6 1.1 0.5 0.3 361.7 153.7 0.0 2.0 0.6 1.7 416.6 2.8 0.8 5.4 8.4 0.7 145.7 0.0 129.7 163.8 0.6 0.0 2.6 0.1 2.5 0.1 76.1 0.0 28.3 0.0 28.2 6.0 18.4 8.1 22.7 3.3 0.3 1.5 0.8 0.3 0.6 MCCD1 ENSG00000204511 "Mitochondrial coiled-coil domain 1" P59942 6 31528962-31530232 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 73 "kidney: 81.8" "Group enriched" "Detected in some" 44 "Distal tubular cells: 401.1;Proximal tubular cells: 414.8" "Group enriched" "Detected in some" 5 "breast cancer: 0.7;endometrial cancer: 0.8;liver cancer: 2.4;renal cancer: 2.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.34e-1)" "unprognostic (2.39e-2)" "unprognostic (2.71e-1)" "unprognostic (3.22e-2)" "prognostic favorable (1.73e-4)" 0.0 0.0 0.1 0.0 0.2 0.1 1.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 81.8 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.5 0.1 0.3 0.4 0.1 0.4 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 401.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 414.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 METTL7B "ALDI, MGC17301" ENSG00000170439 "Methyltransferase like 7B" Q6UX53 12 55681678-55684611 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 133.1;heart muscle: 124.2;liver: 284.3" "Cell type enhanced" "Detected in some" "Hepatocytes: 83.9;Hofbauer cells: 72.7;Proximal enterocytes: 192.4;Proximal tubular cells: 55.6" "Cancer enhanced" "Detected in many" "glioma: 97.9;liver cancer: 97.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "intermediate monocyte: 4.5;myeloid DC: 7.0;naive B-cell: 1.7;non-classical monocyte: 3.3" "Group enriched" "Detected in many" 45 "B-cells: 1.7;dendritic cells: 7.0;monocytes: 4.5" "Cell line enhanced" "Detected in many" "CACO-2: 28.4;CAPAN-2: 56.6;EFO-21: 41.3;Hep G2: 28.7;LHCN-M2: 47.0;OE19: 32.5;THP-1: 42.2;U-87 MG: 41.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA038644 Enhanced Approved Vesicles,Microtubules NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" Microtubules Vesicles "HPA038644: AB_2676130" "unprognostic (7.54e-2)" "unprognostic (7.15e-2)" "unprognostic (5.55e-2)" "unprognostic (3.07e-3)" "unprognostic (6.30e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (2.00e-1)" "unprognostic (2.22e-1)" "unprognostic (1.22e-1)" "unprognostic (2.55e-1)" "unprognostic (2.98e-2)" "unprognostic (5.33e-2)" "unprognostic (2.64e-1)" "unprognostic (2.76e-2)" "unprognostic (7.10e-2)" "prognostic favorable (2.37e-4)" "unprognostic (2.43e-1)" 2.1 1.7 5.5 1.8 5.9 1.2 0.9 4.9 10.8 0.4 5.9 28.5 59.6 0.4 133.1 0.1 3.1 11.7 124.2 13.1 5.9 52.1 284.3 1.6 2.3 8.4 5.5 0.1 2.9 0.2 3.1 10.9 5.0 0.3 23.6 1.3 0.5 0.8 7.4 0.9 55.3 2.1 5.7 4.3 4.2 0.7 11.6 0.2 3.3 10.0 0.5 1.3 0.1 7.7 0.4 21.8 0.1 0.5 4.3 15.3 0.3 0.8 3.2 0.2 1.4 28.4 56.6 11.6 41.3 1.2 1.1 0.1 4.1 0.3 0.8 0.0 5.4 1.2 3.2 28.7 0.0 0.6 0.0 4.0 0.0 1.0 0.0 4.2 0.0 0.0 0.2 0.0 47.0 20.2 0.0 0.4 5.7 32.5 2.7 0.0 1.5 2.7 0.5 0.1 0.1 0.3 2.2 0.0 3.9 0.2 3.8 42.2 0.0 3.1 3.5 0.4 2.9 0.0 0.6 3.5 41.9 9.9 0.2 0.0 0.8 0.0 0.0 4.5 0.0 0.5 0.0 0.0 7.0 1.7 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.4 5.5 5.9 4.9 10.8 13.1 5.9 8.4 5.5 5.0 5.7 11.6 7.7 0.0 0.0 1.5 0.7 0.5 0.0 0.3 0.0 0.0 0.0 0.1 0.1 26.5 22.8 0.6 0.0 0.0 0.5 0.0 29.0 3.9 3.9 0.0 0.1 0.0 0.5 1.2 4.0 0.7 5.1 0.5 2.0 2.6 0.2 0.0 0.8 1.1 83.9 72.7 0.0 0.1 14.0 0.0 17.0 0.0 0.0 0.0 3.3 0.0 0.0 0.2 0.5 0.0 0.0 0.0 4.6 20.7 1.2 0.0 0.1 192.4 55.6 0.0 0.0 0.0 7.8 0.6 0.0 0.1 0.0 0.0 0.7 0.3 0.1 22.2 0.1 MGAM MGA ENSG00000257335 Maltase-glucoamylase O43451 7 141907813-142106747 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Multifunctional enzyme" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 25.5;intestine: 87.6" "Group enriched" "Detected in some" 5 "Late spermatids: 156.4;Proximal enterocytes: 521.4" "Cancer enriched" "Detected in some" 7 "renal cancer: 4.9" "Region enhanced" "Detected in single" "cerebral cortex: 2.3" "Immune cell enriched" "Detected in some" 7 "neutrophil: 13.5" "Lineage enriched" "Detected in single" 102 "granulocytes: 13.5" "Cell line enhanced" "Detected in some" "A549: 1.8;BJ hTERT+: 1.6;HL-60: 2.8;U-937: 4.3;WM-115: 1.0" "Region enriched" "Detected in single" 12 "olfactory bulb: 2.0" "Low region specificity" "Detected in many" HPA002270 Enhanced NA NA 310000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 32: U-937 - Innate immune response" "Cluster 45: Enterocytes - Digestion" "HPA002270: AB_1079366" "unprognostic (1.02e-2)" "unprognostic (1.45e-1)" "unprognostic (1.13e-1)" "unprognostic (6.95e-3)" "unprognostic (2.80e-1)" "unprognostic (7.81e-2)" "unprognostic (7.32e-3)" "unprognostic (3.83e-2)" "unprognostic (4.97e-1)" "unprognostic (2.17e-2)" "unprognostic (6.86e-2)" "unprognostic (1.99e-1)" "prognostic favorable (6.16e-5)" "unprognostic (1.82e-1)" "unprognostic (2.82e-1)" "unprognostic (1.34e-3)" "unprognostic (3.03e-1)" 2.6 0.1 0.2 2.5 0.4 18.1 0.2 0.2 2.3 0.4 0.3 0.5 58.9 0.1 25.5 0.3 1.2 0.4 0.3 0.1 0.3 18.7 0.5 3.2 0.1 0.5 0.4 0.1 0.2 0.0 0.1 0.3 0.6 0.1 0.2 0.0 0.1 7.1 0.1 0.1 87.6 0.4 0.2 12.6 1.8 1.3 0.6 0.4 0.1 1.0 0.0 0.5 0.1 0.4 0.0 1.8 0.1 0.0 0.0 0.0 0.2 0.0 1.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.2 0.0 0.1 0.0 0.0 0.0 4.3 1.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.2 2.3 0.1 0.3 0.5 0.4 0.6 0.2 0.6 0.4 0.0 0.0 2.5 3.3 0.1 0.0 0.0 0.6 0.0 0.2 0.5 0.1 1.4 0.0 3.2 12.9 0.0 0.0 2.8 1.8 1.9 0.1 59.7 0.1 0.2 0.3 1.2 0.0 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.7 17.8 0.0 0.0 2.5 156.4 0.6 1.1 0.0 0.0 0.7 0.6 5.2 1.5 0.6 0.2 16.3 0.4 0.0 0.1 521.4 24.4 6.7 0.0 0.0 0.5 0.1 1.8 1.2 0.0 0.0 0.0 0.4 0.0 7.3 0.3 MIOX ALDRL6 ENSG00000100253 "Myo-inositol oxygenase" Q9UGB7 22 50486784-50490648 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 48 "kidney: 700.9" "Cell type enriched" "Detected in some" 10 "Proximal tubular cells: 4564.6" "Cancer enriched" "Detected in many" 16 "renal cancer: 56.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HDLM-2: 24.9;Hep G2: 5.7;Karpas-707: 12.8;U-266/70: 7.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039451, HPA039562" Enhanced NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 7: Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA039451: AB_2676513, HPA039562: AB_2676574" "unprognostic (2.11e-1)" "unprognostic (4.32e-2)" "unprognostic (2.22e-2)" "unprognostic (1.30e-2)" "unprognostic (9.83e-2)" "unprognostic (5.25e-2)" "unprognostic (1.61e-2)" "unprognostic (3.84e-3)" "unprognostic (2.84e-1)" "unprognostic (4.72e-2)" "unprognostic (1.85e-2)" "unprognostic (9.83e-2)" "prognostic favorable (2.60e-6)" "unprognostic (1.77e-1)" "unprognostic (1.50e-1)" "unprognostic (1.36e-2)" "unprognostic (2.23e-2)" 0.2 0.1 0.1 0.3 0.2 0.2 0.0 0.8 0.5 0.0 0.2 0.8 0.2 0.0 0.2 0.1 0.0 5.3 0.0 0.2 0.2 700.9 0.4 0.0 0.7 0.2 0.2 0.0 1.2 0.0 0.1 0.1 0.3 0.5 0.0 0.1 0.3 0.1 0.0 0.3 0.2 0.0 0.1 0.2 1.1 0.2 0.2 0.2 14.7 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.1 0.3 0.2 0.1 2.0 0.2 0.0 0.0 0.1 0.1 0.2 0.1 0.6 0.4 0.0 0.2 0.2 0.0 0.0 24.9 0.0 0.2 0.4 5.7 2.8 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 1.1 0.1 12.8 0.0 1.2 0.0 0.1 0.2 0.5 0.4 0.1 0.1 0.1 2.6 0.1 0.1 0.3 0.0 0.0 0.6 0.5 0.1 1.4 0.0 0.0 0.5 0.1 0.1 7.8 0.7 0.3 0.1 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.1 0.2 0.8 0.5 0.2 0.2 0.2 0.2 0.3 0.1 0.2 0.3 0.2 0.0 1.7 0.0 13.0 0.8 0.9 0.1 0.0 0.6 0.7 0.8 0.1 1.5 0.0 99.3 0.0 0.0 0.3 0.3 424.6 0.0 0.0 0.1 0.2 0.2 1.2 0.0 0.0 0.9 0.1 0.3 0.0 0.2 0.0 0.1 0.4 0.3 0.1 0.0 0.0 0.9 0.0 0.0 1.6 0.0 0.0 23.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.2 4564.6 0.0 0.5 0.0 0.2 0.1 0.1 0.3 0.0 0.1 0.3 7.8 0.0 0.1 0.9 MLXIPL "bHLHd14, CHREBP, MIO, MONDOB, WBSCR14, WS-bHLH" ENSG00000009950 "MLX interacting protein like" Q9NP71 7 73593194-73624543 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 609.7" "Group enriched" "Detected in many" 4 "Cholangiocytes: 84.4;Enteroendocrine cells: 90.1;Hepatocytes: 286.6;Proximal enterocytes: 108.9" "Cancer enriched" "Detected in many" 6 "liver cancer: 60.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 46.5;K-562: 15.2;SCLC-21H: 25.5;T-47d: 11.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064640 Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "HPA064640: AB_2685309" "unprognostic (1.11e-1)" "unprognostic (1.14e-1)" "unprognostic (2.18e-2)" "unprognostic (4.86e-2)" "unprognostic (5.04e-1)" "unprognostic (1.06e-3)" "unprognostic (3.46e-3)" "unprognostic (9.12e-2)" "unprognostic (1.30e-1)" "unprognostic (1.43e-1)" "unprognostic (6.13e-3)" "unprognostic (4.91e-2)" "unprognostic (2.25e-2)" "unprognostic (1.12e-1)" "unprognostic (3.46e-2)" "unprognostic (2.46e-2)" "unprognostic (7.72e-3)" 72.3 85.1 5.5 0.7 4.1 0.2 51.2 16.3 9.4 3.0 0.2 7.8 58.8 0.6 16.3 3.4 12.9 5.5 3.5 4.5 1.4 36.2 609.7 2.7 0.0 5.6 1.4 4.9 23.1 6.3 13.4 0.0 6.1 3.7 1.5 0.7 8.7 0.8 58.1 4.5 46.8 0.5 1.3 0.3 4.7 30.9 2.2 0.9 7.3 13.8 0.0 2.0 2.7 2.1 0.2 2.5 0.0 5.9 4.8 0.0 0.1 0.0 0.0 0.0 0.0 0.3 7.5 0.0 0.3 0.0 0.6 1.2 0.0 0.0 0.0 0.2 6.1 0.0 4.8 46.5 1.3 0.2 1.7 0.8 0.0 0.0 0.0 0.1 0.0 0.0 15.2 0.0 0.1 6.3 0.1 0.0 0.7 8.2 1.0 0.0 0.0 1.2 0.0 0.1 25.5 0.7 1.0 4.4 0.0 0.1 11.4 6.2 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 4.1 16.3 9.4 4.5 1.4 5.6 1.4 6.1 1.3 2.2 2.1 0.6 0.0 16.2 2.3 1.6 1.1 4.8 0.6 0.6 9.9 1.4 1.3 3.4 84.4 4.7 3.7 20.9 0.1 0.3 3.2 1.9 2.9 3.2 0.7 0.2 2.5 90.1 16.0 33.4 1.0 0.1 6.5 4.6 0.8 0.0 0.1 12.8 286.6 0.4 1.7 29.1 19.6 0.0 11.2 1.5 1.2 2.8 2.8 7.2 30.9 0.2 2.0 1.0 2.0 0.9 1.4 13.9 1.2 0.1 2.2 108.9 14.1 3.2 6.5 0.0 23.9 1.0 5.1 1.1 0.5 0.9 0.5 1.7 0.0 31.9 4.0 MOGAT2 "DGAT2L5, FLJ22644, MGAT2" ENSG00000166391 "Monoacylglycerol O-acyltransferase 2" Q3SYC2 11 75717838-75732958 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 19 "intestine: 48.2;liver: 25.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 73.8;Hepatocytes: 79.6;Intestinal goblet cells: 36.2;Proximal enterocytes: 159.6;Undifferentiated cells: 32.4" "Cancer enhanced" "Detected in many" "liver cancer: 6.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Hep G2: 4.5;RPMI-8226: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA028834 Uncertain NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "HPA028834: AB_10601865" "unprognostic (5.63e-2)" "unprognostic (2.71e-2)" "unprognostic (6.37e-2)" "unprognostic (6.88e-3)" "unprognostic (1.15e-4)" "unprognostic (2.66e-3)" "unprognostic (1.28e-3)" "unprognostic (1.09e-1)" "unprognostic (1.42e-2)" "unprognostic (1.12e-1)" "unprognostic (4.21e-2)" "unprognostic (3.02e-1)" "unprognostic (1.24e-5)" "unprognostic (2.13e-3)" "unprognostic (1.84e-2)" "unprognostic (2.13e-1)" "unprognostic (2.83e-3)" 0.0 0.0 0.0 1.9 0.2 0.0 1.4 0.0 0.1 0.1 0.0 13.9 44.9 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 25.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 12.6 0.0 0.2 0.2 0.0 0.6 48.2 0.7 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.7 0.6 0.3 1.5 0.2 0.0 0.0 0.0 0.0 73.8 0.0 0.0 0.0 0.1 0.0 0.0 2.4 2.7 0.0 0.5 0.0 0.0 2.6 0.1 0.0 0.0 0.4 79.6 0.0 0.0 0.0 36.2 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 21.3 0.0 0.0 0.6 159.6 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 32.4 0.1 MRC1 "bA541I19.1, CD206, CLEC13D, CLEC13DL, MRC1L1" ENSG00000260314 "Mannose receptor C-type 1" P22897 10 17809348-17911164 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Endocytosis, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 122.3" "Group enriched" "Detected in many" 4 "Breast glandular cells: 128.9;Hepatic stellate cells: 397.7;Hofbauer cells: 176.1;Kupffer cells: 361.4;Macrophages: 316.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 16 "myeloid DC: 4.8" "Lineage enriched" "Detected in single" 16 "dendritic cells: 4.8" "Group enriched" "Detected in some" 19 "MOLT-4: 19.3;TIME: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004114, HPA045134, CAB068203" Enhanced NA NA 170000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "CAB068203: AB_2665652, HPA004114: AB_1846270, HPA045134: AB_2679228" "unprognostic (2.20e-1)" "unprognostic (2.07e-1)" "unprognostic (1.03e-2)" "unprognostic (2.58e-1)" "unprognostic (5.62e-2)" "unprognostic (4.30e-1)" "unprognostic (6.36e-3)" "unprognostic (1.35e-1)" "unprognostic (1.05e-2)" "unprognostic (6.05e-2)" "unprognostic (5.61e-2)" "unprognostic (4.12e-1)" "unprognostic (2.94e-2)" "unprognostic (4.97e-2)" "unprognostic (3.05e-2)" "unprognostic (1.74e-2)" "unprognostic (7.02e-2)" 54.4 28.7 0.8 24.0 1.7 0.7 16.3 0.3 3.5 17.2 9.2 16.1 9.9 7.2 1.7 13.1 11.9 27.7 10.2 1.1 0.7 7.6 40.9 122.3 15.2 1.4 0.9 6.2 8.1 4.6 1.5 54.3 1.1 2.2 18.5 0.1 4.9 8.0 1.8 2.8 17.5 30.3 0.7 50.6 9.7 7.5 2.8 8.0 5.5 8.7 3.0 29.0 2.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 19.3 0.0 0.2 0.0 0.0 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 17.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.8 1.7 0.3 3.5 1.1 0.7 1.4 0.9 1.1 0.7 2.8 1.3 4.0 32.1 43.5 1.3 3.5 0.4 0.0 0.0 0.0 0.0 128.9 1.7 3.6 11.5 7.4 0.0 0.0 0.9 1.0 1.4 0.0 0.1 27.3 0.0 0.1 39.0 0.0 3.2 0.8 0.4 1.4 2.5 0.0 0.1 13.9 0.1 397.7 13.1 176.1 0.0 1.3 0.9 0.0 361.4 46.8 19.4 1.5 316.5 0.0 60.9 0.5 0.0 0.0 0.5 0.5 0.1 1.5 0.0 1.0 0.0 2.2 0.1 5.8 0.0 32.9 3.0 2.2 0.4 2.3 1.2 0.4 2.1 4.7 1.7 0.8 0.1 MROH2A HEATR7B1 ENSG00000185038 "Maestro heat like repeat family member 2A" A6NES4 2 233775679-233833423 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 1.7;thyroid gland: 1.6" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 3.4;Early spermatids: 1.3;Hepatocytes: 1.0;Late spermatids: 1.7;Spermatocytes: 1.5" "Cancer enhanced" "Detected in some" "urothelial cancer: 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "RT4: 6.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA052107 Uncertain Uncertain Cytosol NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 15: RT4 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA052107: AB_2681729" "unprognostic (7.00e-2)" "unprognostic (3.37e-3)" "unprognostic (4.77e-1)" "unprognostic (1.65e-2)" "unprognostic (4.03e-1)" "unprognostic (1.71e-1)" "unprognostic (1.87e-1)" "unprognostic (4.41e-2)" "unprognostic (2.69e-1)" "unprognostic (1.67e-1)" "unprognostic (4.32e-2)" "unprognostic (5.05e-2)" "unprognostic (4.06e-9)" "unprognostic (5.65e-2)" "unprognostic (3.90e-2)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.7 0.1 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.4 3.4 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 1.5 0.6 0.6 0.1 0.0 0.0 0.0 0.0 0.3 MS4A4A "CD20L1, MS4A4, MS4A7" ENSG00000110079 "Membrane spanning 4-domains A4A" Q96JQ5 11 60185657-60318080 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 63.1" "Group enriched" "Detected in many" 7 "Hofbauer cells: 376.8;Kupffer cells: 445.0;Macrophages: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 61.2;myeloid DC: 27.6;non-classical monocyte: 82.9;plasmacytoid DC: 27.7" "Group enriched" "Detected in many" 30 "dendritic cells: 27.7;monocytes: 82.9" "Cell line enhanced" "Detected in some" "HEL: 35.6;HMC-1: 45.8;K-562: 154.9" HPA029323 Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 1: K-562 - Erythropoiesis" "Cluster 4: Macrophages - Innate immune response" "HPA029323: AB_10601866" "unprognostic (7.93e-2)" "unprognostic (2.05e-2)" "unprognostic (1.37e-3)" "unprognostic (1.98e-1)" "unprognostic (4.46e-2)" "unprognostic (2.31e-1)" "unprognostic (9.66e-2)" "unprognostic (1.59e-1)" "unprognostic (4.56e-1)" "unprognostic (6.65e-2)" "unprognostic (8.10e-2)" "unprognostic (2.11e-1)" "unprognostic (5.02e-3)" "unprognostic (3.32e-2)" "unprognostic (4.66e-2)" "unprognostic (4.89e-2)" "unprognostic (4.21e-2)" 42.8 24.7 3.5 16.5 3.6 6.1 12.3 3.7 8.6 14.1 4.4 14.0 5.2 4.9 3.4 8.9 11.6 25.8 8.4 3.5 3.9 4.8 15.4 28.0 31.3 4.2 3.4 4.1 4.0 3.3 3.3 63.1 3.6 3.4 16.1 2.0 7.6 4.9 2.3 2.9 13.5 20.0 2.5 33.3 6.6 3.0 5.5 11.5 3.7 10.4 7.5 28.0 3.3 4.3 0.3 0.1 0.1 0.6 0.0 0.2 0.7 0.6 0.0 0.2 0.4 0.3 0.9 0.8 0.4 0.0 0.4 0.3 0.5 0.1 0.6 1.6 0.0 35.6 0.7 0.6 0.1 1.2 45.8 0.4 0.3 0.2 0.8 0.2 0.0 0.4 154.9 4.2 0.6 0.7 0.6 0.9 0.7 0.3 0.1 0.7 0.0 2.5 0.1 1.5 0.5 0.5 0.3 0.3 0.1 0.7 0.7 8.9 0.8 1.5 0.6 0.4 0.2 6.0 0.7 0.5 0.2 0.8 0.2 0.1 9.9 0.0 0.1 61.2 0.2 1.0 0.1 0.1 27.6 0.3 0.2 0.1 0.9 1.8 82.9 27.7 0.1 6.0 3.5 3.6 3.7 8.6 3.5 3.9 4.2 3.4 3.6 2.5 5.5 4.3 2.3 0.0 7.9 0.0 3.0 1.8 0.1 0.0 0.6 0.0 0.3 2.2 3.4 2.8 2.5 0.0 0.0 1.8 7.5 0.0 0.0 0.0 0.7 0.0 0.0 5.7 0.0 13.0 0.1 0.0 2.0 1.6 0.0 0.0 7.6 0.0 47.5 4.6 376.8 0.0 0.1 0.0 0.0 445.0 24.9 1.0 0.9 264.6 3.6 10.3 8.3 0.4 0.0 0.0 0.2 0.2 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 13.1 1.2 1.1 0.1 0.2 0.7 1.8 3.6 1.5 0.1 0.0 0.1 MS4A7 "CD20L4, CFFM4, MS4A8" ENSG00000166927 "Membrane spanning 4-domains A7" Q9GZW8 11 60378485-60395951 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 196.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 311.4;Kupffer cells: 1060.3;Macrophages: 567.5;monocytes: 184.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "intermediate monocyte: 747.4;non-classical monocyte: 1486.0" "Lineage enriched" "Detected in many" 12 "monocytes: 1486.0" "Cell line enriched" "Detected in some" 25 "THP-1: 114.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA017418, CAB026387" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB026387: , HPA017418: AB_1854137" "unprognostic (1.43e-1)" "unprognostic (2.60e-3)" "unprognostic (3.24e-2)" "unprognostic (9.67e-2)" "unprognostic (2.04e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-1)" "unprognostic (9.51e-2)" "unprognostic (3.02e-2)" "unprognostic (4.85e-2)" "unprognostic (5.79e-2)" "unprognostic (1.90e-1)" "unprognostic (1.43e-2)" "unprognostic (4.59e-2)" "unprognostic (3.90e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" 46.9 37.6 6.3 50.9 5.0 10.7 30.7 4.5 13.7 18.2 13.9 21.4 17.6 7.6 4.1 12.7 6.6 46.8 9.9 4.2 8.7 8.0 66.5 75.7 23.2 12.8 10.4 6.0 6.0 9.0 4.7 43.9 11.4 4.9 23.3 1.2 6.7 9.0 1.9 2.3 25.1 15.9 7.4 196.6 14.8 4.7 17.1 18.2 7.3 4.1 18.6 41.2 3.9 18.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 2.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.5 0.1 0.0 0.1 1.1 0.1 0.1 0.0 2.8 0.0 0.1 0.1 0.8 0.5 0.0 0.0 114.2 0.0 0.1 0.1 0.1 0.1 0.2 0.2 3.0 0.0 3.1 0.0 8.3 188.0 2.5 0.8 747.4 1.1 22.3 0.6 0.5 120.9 19.7 0.8 0.4 9.3 0.8 1486.0 3.2 0.9 137.8 6.3 5.0 4.5 13.7 4.2 8.7 12.8 10.4 11.4 7.4 17.1 18.3 5.0 12.8 31.4 0.0 30.6 2.7 0.8 0.0 0.6 3.6 14.7 9.9 2.1 0.0 3.7 9.2 0.0 1.0 1.4 0.3 0.0 0.0 2.4 0.1 0.0 12.2 0.0 10.1 0.1 0.2 1.7 3.9 1.5 0.1 13.9 0.1 11.0 4.7 311.4 0.0 0.2 0.0 0.0 1060.3 93.4 1.2 1.2 567.5 1.8 59.0 184.8 0.4 4.1 0.0 0.3 0.1 1.1 0.0 1.8 1.1 0.0 0.7 7.3 0.5 19.7 2.2 1.2 0.0 0.4 0.9 1.8 1.9 5.3 0.3 0.1 1.0 MSRA ENSG00000175806 "Methionine sulfoxide reductase A" Q9UJ68 8 10054292-10428891 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 86.0;liver: 64.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 625.8;Inhibitory neurons: 318.6;Oligodendrocyte precursor cells: 268.9;Proximal tubular cells: 666.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebellum: 28.4" "Immune cell enhanced" "Detected in some" "eosinophil: 5.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 12.3" "Low region specificity" "Detected in all" "HPA023804, HPA075766" Approved Supported "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" No No 55000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "Plasma membrane, Actin filaments" "HPA023804: AB_1853826, HPA075766: " "unprognostic (1.55e-1)" "unprognostic (4.30e-3)" "unprognostic (1.45e-3)" "unprognostic (1.00e-2)" "unprognostic (4.21e-2)" "unprognostic (1.62e-2)" "unprognostic (1.49e-2)" "unprognostic (6.40e-2)" "unprognostic (9.69e-2)" "unprognostic (1.08e-1)" "unprognostic (1.80e-1)" "unprognostic (4.58e-2)" "unprognostic (1.07e-3)" "unprognostic (6.43e-3)" "unprognostic (4.02e-1)" "unprognostic (6.36e-3)" "unprognostic (3.07e-1)" 17.0 20.4 2.2 1.1 3.0 13.5 16.1 28.4 5.4 9.1 0.0 13.9 1.1 10.7 0.1 11.6 7.4 0.4 29.0 3.8 0.0 86.0 64.0 12.2 0.6 0.0 0.4 6.4 14.5 0.7 9.2 0.8 1.8 9.2 0.6 0.6 10.5 1.0 14.5 9.5 20.1 0.8 0.0 18.6 14.2 15.2 0.3 1.5 9.6 1.3 0.6 11.6 8.2 2.8 0.1 0.9 1.3 4.3 1.2 1.4 0.5 2.5 0.2 0.3 1.7 0.6 2.1 0.0 0.6 2.5 5.8 2.3 0.4 0.1 1.3 0.2 0.0 0.3 1.5 2.2 4.3 0.8 12.3 0.4 3.2 0.3 0.0 1.4 0.6 0.3 0.4 0.2 4.9 0.1 0.0 0.3 0.6 3.3 0.8 1.6 1.3 2.0 1.1 1.1 2.5 1.5 4.6 0.2 0.5 0.4 2.3 2.8 2.6 1.7 2.0 0.4 1.2 0.2 0.1 0.7 4.8 0.8 3.1 0.5 1.9 5.6 0.4 1.2 0.3 0.6 0.4 0.3 1.2 0.1 0.3 0.2 2.2 0.7 0.9 0.2 0.3 0.2 2.2 3.0 28.4 5.4 3.8 0.0 0.0 0.4 1.8 0.0 0.3 2.8 44.1 0.0 7.4 152.8 21.4 16.4 29.3 10.8 14.2 10.1 21.2 21.8 21.6 25.8 7.2 25.8 31.3 7.7 12.4 26.4 92.0 32.3 80.6 13.6 8.7 30.3 9.6 3.4 625.8 47.1 4.6 13.1 14.8 11.8 80.7 13.7 19.6 97.2 47.0 16.8 318.6 20.8 4.1 33.6 48.3 167.9 9.3 38.0 30.2 85.3 22.3 14.6 11.3 268.9 60.7 51.1 37.8 9.8 16.2 33.8 195.5 666.1 5.6 6.2 13.1 11.3 16.9 39.3 26.5 20.1 14.1 8.3 18.0 14.1 24.5 31.1 MSRB1 "SelR, SelX, SepR, SEPX1" ENSG00000198736 "Methionine sulfoxide reductase B1" Q9NZV6 16 1938229-1943293 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 234.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 275.6;monocytes: 178.7;Proximal tubular cells: 496.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 1414.9;neutrophil: 3051.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 3051.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008650, HPA043463, HPA069557" Enhanced Enhanced Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "CAB008650: AB_1619225, HPA043463: AB_2678489, HPA069557: AB_2686153" "unprognostic (3.93e-2)" "unprognostic (3.68e-1)" "unprognostic (1.32e-1)" "unprognostic (9.61e-2)" "unprognostic (1.76e-2)" "unprognostic (1.15e-1)" "unprognostic (2.19e-1)" "unprognostic (1.49e-1)" "unprognostic (2.88e-2)" "unprognostic (4.90e-2)" "unprognostic (5.29e-2)" "unprognostic (3.60e-1)" "unprognostic (4.27e-2)" "unprognostic (8.46e-2)" "unprognostic (4.92e-2)" "unprognostic (7.31e-2)" "unprognostic (4.59e-3)" 28.1 15.1 26.2 31.8 27.3 96.3 21.3 27.8 28.4 17.5 25.8 36.7 29.4 29.5 11.2 45.3 33.5 23.2 47.3 25.6 26.8 80.3 234.2 30.4 17.7 29.3 28.0 16.4 149.6 14.8 14.5 13.2 27.1 32.0 17.4 2.7 16.5 29.2 76.0 31.1 27.5 36.8 27.5 67.0 33.3 17.7 28.5 13.7 12.5 93.6 12.2 40.8 20.1 27.1 23.6 59.1 21.3 50.4 39.9 17.0 36.4 27.8 36.0 41.2 35.6 96.2 25.5 22.7 90.6 33.5 36.0 37.9 36.3 25.2 12.8 127.7 41.1 17.5 20.5 154.9 36.1 49.3 40.3 32.0 21.9 29.6 6.0 12.9 41.9 28.8 28.2 12.3 22.3 131.2 28.2 82.7 29.2 42.7 33.5 40.3 29.3 106.0 66.0 37.2 20.5 26.9 32.3 35.6 17.3 13.9 38.7 87.9 24.8 12.3 33.7 24.3 16.7 32.0 53.4 42.4 12.5 47.4 22.0 493.5 412.0 1414.9 31.9 194.8 32.2 28.0 26.5 26.7 171.2 28.3 20.5 22.7 3051.8 42.2 182.9 73.2 45.9 226.7 26.2 27.3 27.8 28.4 25.6 26.8 29.3 28.0 27.1 27.5 28.5 27.1 24.9 9.6 13.4 3.9 10.0 6.5 9.1 21.5 8.0 6.5 27.9 21.3 36.1 32.9 14.9 33.1 4.2 33.3 12.3 69.1 93.9 65.9 5.9 23.9 13.4 15.4 60.3 21.5 0.8 111.2 121.4 13.7 11.7 17.0 4.5 12.2 20.7 275.6 63.5 8.4 1.2 38.6 34.6 59.2 21.2 13.9 9.3 37.9 16.0 2.8 178.7 22.5 25.7 1.5 2.9 66.0 62.8 23.0 13.0 16.3 97.3 496.8 37.9 4.2 0.0 8.1 22.8 28.9 8.7 11.1 9.5 38.6 10.6 14.8 33.5 21.9 MTNR1A MEL-1A-R ENSG00000168412 "Melatonin receptor 1A" P48039 4 186533655-186555567 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.0;intestine: 1.2;kidney: 2.1;testis: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "cerebellum: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (7.99e-2)" "unprognostic (2.27e-1)" "unprognostic (2.16e-1)" "unprognostic (3.67e-1)" "unprognostic (2.14e-1)" "unprognostic (9.88e-2)" "unprognostic (9.20e-2)" "unprognostic (8.81e-2)" 0.0 0.0 0.0 0.6 0.1 0.0 0.0 1.0 0.1 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MTTP "ABL, MTP" ENSG00000138823 "Microsomal triglyceride transfer protein" P55157 4 99564081-99623997 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "intestine: 275.2;liver: 266.6" "Group enriched" "Detected in many" 9 "Hepatocytes: 244.2;Proximal enterocytes: 605.4" "Cancer enriched" "Detected in many" 13 "liver cancer: 28.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 10.8;Hep G2: 12.2" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA051170, HPA054862" Uncertain Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 640000 "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Endoplasmic reticulum, Cytosol" "HPA051170: , HPA054862: AB_2682628" "unprognostic (1.66e-2)" "unprognostic (1.14e-1)" "unprognostic (5.64e-2)" "unprognostic (5.33e-2)" "unprognostic (3.49e-3)" "unprognostic (7.38e-2)" "unprognostic (1.05e-1)" "unprognostic (2.74e-2)" "unprognostic (1.08e-1)" "unprognostic (3.66e-2)" "unprognostic (1.00e-2)" "unprognostic (1.62e-1)" "unprognostic (1.27e-3)" "unprognostic (2.02e-2)" "unprognostic (3.64e-1)" "unprognostic (1.53e-2)" "unprognostic (1.31e-1)" 0.3 0.1 0.9 0.2 0.9 0.0 0.2 0.8 0.9 0.1 0.3 1.3 243.2 0.1 1.0 0.1 0.6 1.3 0.9 0.8 1.5 12.9 266.6 0.3 0.3 1.1 1.6 2.0 0.0 0.0 0.5 0.0 1.3 0.5 0.3 5.6 0.1 0.2 0.4 0.1 275.2 0.5 1.2 0.0 0.8 9.6 1.2 0.2 0.1 0.3 0.1 0.9 0.0 1.9 0.0 0.2 10.8 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.1 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.2 0.1 12.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.6 0.5 0.1 0.2 0.1 0.1 1.0 0.0 0.0 0.7 0.8 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.8 0.9 0.8 1.5 1.1 1.6 1.3 1.2 1.2 1.9 0.1 0.0 0.0 4.6 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.4 2.8 4.3 0.1 1.8 0.0 0.2 0.2 0.2 0.0 0.0 44.2 1.0 0.1 0.1 0.0 2.7 1.6 0.0 0.0 0.8 1.5 0.2 0.0 30.1 3.6 244.2 0.1 0.0 0.7 16.7 2.0 3.5 0.0 12.0 0.9 0.2 0.0 0.0 0.6 0.0 0.0 0.0 2.0 0.2 12.5 0.4 0.1 0.0 605.4 23.5 1.0 0.0 6.6 0.5 0.5 32.1 5.7 0.0 0.0 0.0 0.4 12.0 21.0 0.0 MYCT1 "FLJ21269, MTLC" ENSG00000120279 "MYC target 1" Q8N699 6 152697895-152724567 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 49.6" "Group enriched" "Detected in some" 5 "Adipocytes: 123.0;Endothelial cells: 141.3;Hepatic stellate cells: 230.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 33 "eosinophil: 30.7" "Lineage enriched" "Detected in single" 248 "granulocytes: 30.7" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 124.6;TIME: 104.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047992 Approved Nucleoplasm,Vesicles NA NA 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Vesicles "HPA047992: " "unprognostic (2.92e-1)" "unprognostic (1.82e-1)" "unprognostic (5.95e-2)" "unprognostic (2.06e-1)" "unprognostic (6.73e-2)" "unprognostic (6.80e-2)" "unprognostic (4.64e-3)" "unprognostic (6.78e-2)" "unprognostic (9.90e-2)" "unprognostic (2.10e-1)" "unprognostic (2.66e-2)" "unprognostic (2.18e-2)" "prognostic unfavorable (4.73e-4)" "unprognostic (1.26e-3)" "unprognostic (1.08e-1)" "unprognostic (1.25e-1)" "unprognostic (3.36e-2)" 26.6 3.2 6.8 5.2 6.9 1.2 21.4 6.9 10.2 9.0 5.2 6.1 3.5 10.1 4.5 4.6 9.2 10.5 17.1 6.3 7.1 6.6 13.1 15.6 6.2 7.7 6.9 3.6 2.7 4.3 2.2 20.7 8.6 4.4 5.8 1.0 3.7 3.8 12.8 4.7 5.6 12.4 6.8 49.6 4.5 1.8 10.0 2.5 12.2 20.5 3.0 8.1 7.3 7.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 17.7 0.1 0.0 0.2 0.0 0.1 0.0 23.0 0.3 0.0 0.7 0.1 0.1 0.0 0.2 0.2 0.3 0.0 124.6 0.0 0.3 0.3 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 2.1 0.0 0.0 104.4 0.5 0.8 1.5 0.0 1.1 0.0 15.6 0.0 0.0 0.0 0.9 0.0 30.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.6 6.8 6.9 6.9 10.2 6.3 7.1 7.7 6.9 8.6 6.8 10.0 7.5 123.0 0.0 5.2 0.7 0.8 7.1 0.2 0.1 2.8 0.2 0.4 0.9 3.1 2.8 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 10.2 1.3 0.2 141.3 0.0 13.7 0.1 0.2 0.0 4.0 0.0 0.1 1.3 0.0 230.6 2.1 0.1 0.0 0.1 0.0 0.0 7.3 7.3 3.7 0.3 13.3 14.2 30.9 0.1 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.6 0.5 0.0 0.0 17.7 0.0 0.0 1.5 2.2 0.1 0.1 0.5 5.5 0.0 0.9 0.5 0.0 0.7 MYLK3 "caMLCK, MLCK" ENSG00000140795 "Myosin light chain kinase 3" Q32MK0 16 46702282-46790407 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 103.4;skeletal muscle: 46.5;tongue: 72.6" "Group enriched" "Detected in some" 12 "Cardiomyocytes: 169.0;Endometrial ciliated cells: 44.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 12.9;HEL: 40.2;K-562: 6.5;SK-BR-3: 7.9" "Group enriched" "Detected in some" 7 "cerebral cortex: 9.6;hippocampal formation: 5.1" "Region enriched" "Detected in single" 5 "hippocampal formation: 3.5" HPA073447 Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm Vesicles "HPA073447: AB_2732225" "unprognostic (6.01e-4)" "unprognostic (2.19e-1)" "unprognostic (2.64e-1)" "unprognostic (1.77e-2)" "unprognostic (1.84e-1)" "unprognostic (2.94e-3)" "unprognostic (2.60e-1)" "unprognostic (4.73e-2)" "unprognostic (3.33e-2)" "unprognostic (2.41e-2)" "unprognostic (6.58e-3)" "unprognostic (1.83e-1)" "unprognostic (4.16e-2)" "unprognostic (2.57e-2)" "unprognostic (2.52e-1)" "unprognostic (1.08e-2)" "unprognostic (2.97e-1)" 0.0 0.1 1.9 0.1 1.7 0.3 0.1 1.1 2.3 0.4 1.7 0.0 0.1 0.3 0.8 4.3 1.7 0.2 103.4 2.5 2.8 1.1 0.1 0.4 0.2 9.8 12.2 0.3 0.1 0.0 0.4 0.5 8.2 2.2 0.1 0.2 2.1 0.1 46.5 0.1 0.1 0.2 5.9 0.1 0.1 6.0 1.9 0.1 0.1 72.6 0.1 0.0 0.0 3.0 0.0 0.1 0.1 0.1 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.8 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.2 2.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 6.5 0.3 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.4 0.0 7.9 0.2 3.5 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.5 0.1 0.3 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 1.9 1.7 1.1 2.3 2.5 2.8 9.8 12.2 8.2 5.9 1.9 3.0 0.2 0.0 3.3 0.7 0.5 0.0 0.7 0.0 0.0 0.9 1.3 0.0 169.0 0.0 3.7 0.0 2.1 2.0 0.2 0.0 0.0 0.0 8.1 44.8 7.1 1.7 0.0 0.0 0.9 0.2 0.5 6.7 0.0 2.2 1.3 1.6 0.7 0.1 0.4 0.0 0.6 0.0 0.0 0.0 0.0 7.2 0.6 0.8 0.0 0.0 0.2 0.8 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.8 0.0 0.2 8.7 1.3 0.0 4.9 2.7 1.0 0.7 0.0 0.0 0.3 0.8 0.7 0.0 0.8 MYO7B ENSG00000169994 "Myosin VIIB" Q6PIF6 2 127535802-127637729 "Predicted intracellular proteins" Differentiation "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 113.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 127.7;Intestinal goblet cells: 48.3;Paneth cells: 74.9;Proximal enterocytes: 151.4;Undifferentiated cells: 45.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 17.2" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.7;naive B-cell: 5.9" "Group enriched" "Detected in many" 22 "B-cells: 5.9;dendritic cells: 2.6;monocytes: 5.7" "Cell line enriched" "Detected in some" 10 "MOLT-4: 286.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA039131 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" "HPA039131: AB_10672771" "unprognostic (4.10e-3)" "unprognostic (3.81e-2)" "unprognostic (3.80e-2)" "unprognostic (2.23e-4)" "unprognostic (1.14e-2)" "unprognostic (2.23e-1)" "unprognostic (2.07e-1)" "unprognostic (8.51e-2)" "unprognostic (3.76e-1)" "unprognostic (3.86e-2)" "unprognostic (2.32e-1)" "unprognostic (1.03e-1)" "prognostic favorable (1.25e-4)" "unprognostic (2.80e-2)" "unprognostic (8.76e-2)" "unprognostic (1.57e-1)" "unprognostic (2.88e-1)" 0.1 0.0 0.2 4.9 0.2 6.5 0.1 0.2 0.3 0.0 0.0 35.9 113.2 0.0 6.7 0.3 0.4 13.0 0.2 0.7 1.8 8.5 0.3 1.0 4.0 0.5 1.1 0.0 0.2 0.0 0.0 1.7 1.1 0.1 25.3 0.0 0.1 0.2 0.8 0.3 84.4 1.2 0.5 11.3 0.4 1.4 0.3 9.0 0.2 0.0 1.6 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.0 14.5 5.1 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.2 0.0 28.1 0.0 0.0 0.2 0.0 286.1 0.8 0.0 0.5 1.7 0.5 1.9 0.3 0.5 0.0 0.1 0.1 0.0 2.4 0.0 0.0 0.1 0.5 0.1 0.6 8.6 0.4 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.7 0.1 0.0 2.2 0.0 0.8 0.0 0.0 2.6 5.9 0.0 0.2 0.1 0.0 1.4 0.7 0.0 2.4 0.2 0.2 0.2 0.3 0.7 1.8 0.5 1.1 1.1 0.5 0.3 0.8 2.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 12.8 0.0 5.5 0.0 0.1 1.5 127.7 1.9 0.2 0.1 0.0 0.0 1.0 25.8 0.0 0.2 0.2 2.0 0.1 1.5 0.0 0.0 0.1 2.9 0.2 0.1 0.0 0.4 48.3 0.0 0.0 0.3 0.4 0.0 1.0 0.0 0.0 0.8 0.0 0.0 0.5 0.1 1.6 74.9 0.0 0.0 0.0 151.4 9.9 0.0 0.0 0.0 2.8 0.1 0.6 1.1 0.0 0.1 0.3 0.6 0.0 45.7 0.1 MYOM3 FLJ35961 ENSG00000142661 "Myomesin 3" Q5VTT5 1 24056035-24112135 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "heart muscle: 222.5;skeletal muscle: 321.5;tongue: 255.9" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 198.3" "Cancer enhanced" "Detected in some" "renal cancer: 6.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A549: 4.6;Hep G2: 18.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA028132, HPA028340" Approved "Golgi apparatus,Vesicles,Cytokinetic bridge" Yes No 830000 "Cluster 38: Heart - Muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Vesicles "Golgi apparatus, Cytokinetic bridge" "HPA028132: AB_10599293, HPA028340: " "unprognostic (8.59e-2)" "unprognostic (2.85e-2)" "unprognostic (2.39e-1)" "unprognostic (8.60e-3)" "unprognostic (1.52e-2)" "unprognostic (7.31e-2)" "unprognostic (3.00e-2)" "unprognostic (1.40e-2)" "unprognostic (4.66e-1)" "unprognostic (2.21e-1)" "unprognostic (2.73e-4)" "unprognostic (2.09e-1)" "prognostic favorable (4.28e-6)" "unprognostic (2.77e-2)" "unprognostic (1.60e-3)" "unprognostic (7.75e-2)" "unprognostic (1.68e-1)" 0.4 0.2 0.0 0.2 0.0 0.0 0.7 0.3 0.1 0.2 0.0 0.6 1.1 0.3 0.0 6.0 0.9 0.4 222.5 0.1 0.1 31.4 0.2 0.3 0.1 0.1 0.1 0.1 1.2 0.0 0.0 0.0 0.1 4.5 0.7 1.2 7.1 0.0 321.5 2.2 5.2 0.2 0.0 0.0 0.2 9.0 0.0 1.7 0.3 255.9 0.1 0.1 0.4 0.2 0.1 4.6 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 1.3 0.0 1.9 0.6 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.8 18.1 0.0 0.1 0.1 0.5 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.4 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.2 0.2 0.1 1.0 0.2 0.5 0.6 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.0 0.6 0.2 0.1 0.6 0.0 0.1 0.6 198.3 0.0 0.0 3.7 0.0 0.0 0.1 3.6 1.9 0.1 16.2 0.4 0.0 1.6 1.2 0.0 0.4 0.4 0.0 6.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.3 1.7 0.0 0.0 0.7 10.3 0.6 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.2 2.5 2.4 0.0 0.0 0.2 13.0 33.2 0.0 2.5 6.6 10.0 1.3 0.0 0.2 0.0 0.6 0.0 0.3 2.3 2.2 0.3 NAT8 "ATase2, GLA, Hcml1, TSC501" ENSG00000144035 "N-acetyltransferase 8 (putative)" Q9UHE5 2 73640723-73642422 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "kidney: 732.4" "Cell type enriched" "Detected in some" 13 "Proximal tubular cells: 2565.5" "Cancer enriched" "Detected in some" 5 "renal cancer: 242.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 15 "Hep G2: 10.7" "Low region specificity" "Detected in all" "HPA067855, HPA074519" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Endoplasmic reticulum" "HPA067855: AB_2732774, HPA074519: AB_2686699" "unprognostic (4.51e-2)" "unprognostic (6.36e-2)" "unprognostic (1.95e-1)" "unprognostic (1.81e-1)" "unprognostic (1.98e-1)" "unprognostic (4.95e-3)" "unprognostic (2.46e-1)" "unprognostic (1.90e-2)" "unprognostic (9.42e-2)" "unprognostic (1.82e-1)" "unprognostic (2.13e-2)" "unprognostic (8.60e-2)" "unprognostic (1.37e-3)" "unprognostic (2.07e-2)" "unprognostic (4.11e-3)" "unprognostic (2.13e-2)" "unprognostic (8.36e-5)" 0.1 0.3 1.1 0.1 0.5 0.1 0.2 0.1 0.7 0.2 0.0 1.1 4.6 0.1 0.0 0.0 1.2 0.6 0.1 0.8 0.8 732.4 82.7 0.2 0.0 0.6 0.3 1.3 0.2 0.0 0.6 0.0 0.1 0.2 0.1 1.8 0.1 0.1 0.0 0.0 7.2 0.1 0.4 1.1 0.6 0.5 1.0 0.0 0.1 0.0 0.0 0.1 0.1 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.5 0.1 0.7 0.8 0.8 0.6 0.3 0.1 0.4 1.0 0.8 0.0 0.0 0.0 0.0 19.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 36.8 0.0 0.0 0.0 0.3 187.9 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 22.9 51.1 0.0 0.0 0.0 1.1 0.0 1.0 0.4 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 61.3 2565.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.6 0.1 NCKAP5 "ERIH1, ERIH2, NAP5" ENSG00000176771 "NCK associated protein 5" O14513 2 132671788-133568463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 34.8;lung: 11.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 262.8;Astrocytes: 478.6;Oligodendrocyte precursor cells: 774.6;Oligodendrocytes: 2156.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "AF22: 46.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034639, HPA044859" Uncertain Approved "Nucleoli,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoli "Golgi apparatus, Plasma membrane, Cytosol" "HPA034639: AB_10669678, HPA044859: AB_2679114" "unprognostic (2.54e-1)" "unprognostic (1.95e-2)" "unprognostic (2.30e-2)" "unprognostic (2.58e-2)" "unprognostic (2.49e-2)" "unprognostic (3.13e-1)" "unprognostic (7.07e-2)" "unprognostic (1.90e-1)" "unprognostic (1.96e-2)" "unprognostic (1.82e-2)" "unprognostic (1.46e-1)" "unprognostic (2.93e-1)" "unprognostic (1.06e-11)" "unprognostic (4.56e-2)" "unprognostic (1.17e-1)" "unprognostic (8.95e-2)" "unprognostic (1.03e-1)" 1.9 1.0 9.6 0.5 31.3 0.0 3.0 18.6 12.3 1.2 2.5 1.2 2.2 0.4 0.6 4.0 0.4 0.7 2.6 9.5 14.5 4.1 3.9 11.4 1.3 23.4 28.6 2.4 0.9 0.6 0.6 2.6 22.9 0.8 1.0 4.7 2.1 0.3 0.5 2.1 3.2 0.4 10.1 1.7 1.7 1.1 28.6 0.8 1.1 0.6 1.0 0.5 2.0 34.8 0.0 2.2 46.2 0.0 0.1 0.4 0.2 0.7 8.3 0.7 0.8 0.0 0.1 3.6 0.0 0.5 0.5 0.2 0.3 0.7 2.5 0.0 0.3 0.0 7.1 0.0 0.0 0.0 0.0 0.5 3.8 4.4 0.6 7.2 0.8 0.0 0.0 0.0 1.3 0.5 0.0 0.0 1.1 0.3 1.4 0.4 0.0 1.9 1.1 1.1 0.2 1.4 0.0 1.7 2.4 0.4 0.7 0.0 2.4 0.3 0.4 6.7 0.1 0.2 0.0 1.3 0.4 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 31.3 18.6 12.3 9.5 14.5 23.4 28.6 22.9 10.1 28.6 34.8 6.0 262.8 13.3 478.6 0.6 8.9 0.7 1.4 15.4 179.6 14.5 10.8 16.8 0.0 28.6 1.8 41.7 0.1 0.1 5.3 3.9 0.3 6.8 1.1 1.1 2.9 3.6 0.0 16.4 0.2 0.2 6.8 7.7 1.4 1.3 0.0 0.7 6.3 0.6 33.7 41.3 5.4 10.2 7.9 32.2 3.3 26.4 6.2 1.8 147.1 4.1 56.9 0.0 774.6 2156.8 1.0 5.2 7.5 0.0 0.5 20.7 14.0 1.2 7.8 6.6 8.7 24.7 0.1 1.3 15.5 2.8 0.0 0.7 0.0 1.6 1.5 NECAB2 EFCBP2 ENSG00000103154 "N-terminal EF-hand calcium binding protein 2" Q7Z6G3 16 83968244-84002776 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 106.4" "Cell type enhanced" "Detected in some" "Early spermatids: 16.6;Hepatocytes: 10.7;Inhibitory neurons: 22.2;Late spermatids: 49.2;Muller glia cells: 17.8;Proximal tubular cells: 27.8" "Cancer enhanced" "Detected in many" "liver cancer: 7.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 66 "neutrophil: 55.4" "Lineage enriched" "Detected in single" 66 "granulocytes: 55.4" "Cell line enhanced" "Detected in some" "AF22: 10.1;MCF7: 6.8;SCLC-21H: 37.6;U-87 MG: 12.2" "Low region specificity" "Detected in all" "HPA013998, HPA014144, CAB068211" Enhanced Supported NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB068211: AB_2665678, HPA013998: AB_1848016, HPA014144: AB_1848017" "unprognostic (5.27e-2)" "unprognostic (1.14e-1)" "unprognostic (5.50e-2)" "unprognostic (3.48e-5)" "unprognostic (3.45e-2)" "unprognostic (4.20e-2)" "unprognostic (6.74e-2)" "unprognostic (8.79e-2)" "unprognostic (4.15e-1)" "unprognostic (2.59e-1)" "unprognostic (5.75e-3)" "unprognostic (2.14e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (8.89e-3)" "unprognostic (3.48e-1)" "unprognostic (8.61e-3)" "unprognostic (3.75e-2)" 0.9 0.5 67.8 0.6 73.0 0.5 0.7 20.3 106.4 2.0 24.9 1.3 1.2 1.2 0.3 0.1 0.4 0.5 1.2 80.5 62.0 11.1 26.0 0.5 0.2 32.1 50.7 0.5 1.9 6.7 16.2 0.3 80.2 0.3 0.2 3.1 0.1 0.1 0.2 0.2 1.2 0.4 24.9 1.6 1.8 10.5 59.4 0.2 0.5 0.2 0.0 0.3 0.2 31.4 0.2 4.4 10.1 0.0 0.0 1.4 0.1 0.1 0.2 0.1 0.1 0.3 0.2 0.0 1.6 0.2 0.8 0.0 1.9 0.0 0.0 0.1 2.9 0.0 0.0 0.5 0.1 0.0 1.7 0.5 0.2 0.3 0.1 0.2 0.1 0.0 0.2 0.1 0.0 6.8 0.0 0.0 5.0 0.4 0.6 0.1 0.0 0.6 0.0 0.0 37.6 1.5 0.0 0.2 3.1 1.4 5.2 1.4 0.3 0.2 2.8 0.4 0.0 0.1 0.0 0.0 12.2 0.5 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.4 0.0 0.0 0.0 0.0 0.1 67.8 73.0 20.3 106.4 80.5 62.0 32.1 50.7 80.2 24.9 59.4 31.4 0.1 0.0 0.0 4.6 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.0 16.6 0.0 0.1 0.1 7.2 0.0 2.2 0.0 0.0 0.3 0.0 0.1 0.0 0.6 0.0 10.7 3.4 0.0 22.2 0.0 0.0 0.0 0.0 49.2 0.3 0.3 0.0 3.7 0.2 17.8 0.0 4.0 0.6 0.0 0.0 0.7 0.0 0.0 0.3 27.8 0.0 0.3 0.0 0.1 0.0 2.1 3.3 0.0 0.0 0.0 0.1 0.3 0.0 0.0 NGEF ARHGEF27 ENSG00000066248 "Neuronal guanine nucleotide exchange factor" Q8N5V2 2 232878701-233013256 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 56.2;brain: 129.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 38.0;Excitatory neurons: 105.9;Proximal enterocytes: 66.7" "Cancer enhanced" "Detected in many" "testis cancer: 22.5" "Region enhanced" "Detected in many" "basal ganglia: 129.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 53.9;HDLM-2: 45.3;HeLa: 21.6;PC-3: 57.0;T-47d: 32.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 167.6;cerebral cortex: 133.8;hippocampal formation: 73.0" HPA008160 Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA008160: AB_1854450" "unprognostic (3.92e-1)" "unprognostic (1.78e-1)" "unprognostic (4.12e-3)" "unprognostic (1.66e-1)" "unprognostic (5.25e-2)" "unprognostic (5.46e-2)" "unprognostic (1.15e-1)" "unprognostic (2.39e-3)" "unprognostic (5.41e-3)" "unprognostic (2.58e-1)" "unprognostic (6.94e-3)" "unprognostic (1.24e-1)" "unprognostic (6.16e-2)" "unprognostic (2.31e-1)" "unprognostic (1.10e-1)" "unprognostic (2.80e-2)" "unprognostic (2.74e-1)" 1.1 56.2 16.3 2.2 129.6 0.1 1.9 0.0 59.4 4.1 0.0 14.2 42.7 5.0 4.1 10.3 4.8 3.1 2.2 19.8 0.0 7.0 35.5 0.7 0.2 0.0 0.0 2.0 6.0 11.9 2.7 0.3 0.0 1.8 10.5 1.4 2.0 0.7 0.9 30.3 31.3 6.7 0.0 0.4 10.7 3.7 0.2 0.0 0.9 0.7 0.3 1.8 5.2 29.4 53.9 15.4 0.6 0.2 0.2 8.2 0.9 0.9 0.1 0.4 0.0 0.7 5.2 0.0 15.2 10.9 5.5 6.9 11.6 3.0 0.4 45.3 3.8 0.1 21.6 16.7 0.2 0.0 0.3 0.0 0.2 3.5 0.6 0.2 1.9 0.2 0.2 0.2 0.5 4.0 0.0 0.1 1.3 0.2 57.0 0.0 0.0 0.1 1.0 1.4 1.9 0.4 6.6 3.3 0.1 2.0 32.2 0.4 0.0 0.5 4.5 0.3 1.0 0.5 0.2 0.0 3.8 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 129.6 0.0 59.4 19.8 0.0 0.0 0.0 0.0 0.0 0.2 29.4 0.0 0.0 0.0 10.4 0.0 9.9 1.2 1.2 2.8 0.3 2.1 1.4 2.4 4.3 0.5 0.0 0.0 0.1 0.0 38.0 0.0 3.9 0.7 9.1 0.9 0.4 4.9 0.0 105.9 10.5 0.3 0.7 17.3 2.0 0.0 0.3 0.4 20.4 0.1 1.7 12.8 14.6 0.0 0.3 0.6 2.0 0.0 0.3 1.8 6.5 0.0 5.5 0.0 4.5 6.0 12.1 23.5 1.2 0.1 0.5 66.7 9.8 2.5 0.2 0.0 0.2 0.3 1.1 0.8 3.8 7.5 0.0 0.2 0.5 20.2 1.1 NOVA2 "ANOVA, NOVA-2, NOVA3" ENSG00000104967 "NOVA alternative splicing regulator 2" Q9UNW9 19 45933734-45974044 "Human disease related genes, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.7" "Cell type enhanced" "Detected in some" "Adipocytes: 39.4;Bipolar cells: 56.7;Endothelial cells: 32.0;Excitatory neurons: 21.8;Hepatic stellate cells: 42.5;Horizontal cells: 21.9;Inhibitory neurons: 20.9" "Cancer enriched" "Detected in many" 4 "glioma: 5.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.7;HDLM-2: 11.0;HUVEC TERT2: 16.9;SH-SY5Y: 5.6;TIME: 25.8;U-2 OS: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045607 Enhanced Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" No No "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 56: Bipolar cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Nuclear bodies" "HPA045607: AB_10962628" "unprognostic (9.84e-2)" "unprognostic (2.07e-1)" "unprognostic (9.68e-2)" "unprognostic (2.01e-1)" "unprognostic (1.79e-1)" "unprognostic (3.04e-3)" "unprognostic (1.46e-1)" "unprognostic (6.21e-2)" "unprognostic (2.36e-1)" "unprognostic (3.02e-3)" "unprognostic (6.42e-5)" "unprognostic (1.16e-1)" "prognostic unfavorable (3.04e-4)" "unprognostic (5.05e-2)" "unprognostic (2.54e-1)" "unprognostic (1.41e-1)" "unprognostic (8.31e-2)" 6.7 1.9 12.4 0.7 15.1 0.0 5.7 0.5 16.7 3.2 0.0 1.8 0.6 3.4 0.6 1.4 2.9 1.4 6.7 16.0 5.8 4.7 1.0 9.3 0.5 4.6 3.0 1.2 1.1 1.0 6.2 3.9 3.6 2.3 0.5 5.6 1.1 0.8 2.3 1.1 1.7 2.0 0.6 1.5 1.5 2.0 4.6 0.4 4.5 2.5 0.2 2.5 2.0 9.8 0.0 0.1 9.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 1.3 0.0 0.0 11.0 0.4 0.0 0.1 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 25.8 0.0 5.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 15.1 0.5 16.7 16.0 5.8 4.6 3.0 3.6 0.6 4.6 9.8 39.4 0.0 0.0 5.9 0.1 0.6 0.2 0.0 0.6 56.7 0.1 0.5 3.4 1.5 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 3.8 0.1 0.1 32.0 0.0 0.0 21.8 0.2 0.0 1.2 0.0 0.1 0.0 0.1 42.5 0.5 0.1 21.9 20.9 0.0 0.0 1.6 1.5 3.5 0.0 0.1 0.0 9.4 0.0 1.3 0.0 11.6 9.5 0.2 0.0 0.4 1.2 0.3 0.0 0.0 0.0 3.3 0.0 0.6 0.6 2.4 2.3 0.3 0.1 0.0 0.5 0.4 0.0 0.3 NOX4 "KOX, KOX-1" ENSG00000086991 "NADPH oxidase 4" Q9NPH5 11 89324353-89498187 "Predicted membrane proteins, Transporters" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "kidney: 138.0" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 164.0" "Cancer enhanced" "Detected in many" "renal cancer: 5.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 14.3;HUVEC TERT2: 27.7;TIME: 70.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.91e-2)" "unprognostic (1.08e-1)" "unprognostic (1.74e-3)" "unprognostic (6.58e-3)" "unprognostic (1.92e-1)" "unprognostic (2.33e-1)" "unprognostic (8.83e-3)" "unprognostic (8.95e-3)" "unprognostic (3.80e-1)" "unprognostic (6.88e-2)" "unprognostic (1.56e-2)" "unprognostic (1.73e-1)" "prognostic favorable (6.14e-4)" "unprognostic (1.99e-4)" "unprognostic (9.71e-2)" "unprognostic (5.69e-2)" "unprognostic (3.03e-3)" 7.8 0.7 0.7 0.7 1.2 0.2 3.8 0.7 1.2 1.5 0.0 1.2 0.2 4.9 0.4 0.4 1.3 2.4 7.6 0.4 0.6 138.0 0.3 1.5 0.2 1.0 0.7 0.8 0.3 3.6 0.9 3.1 0.9 1.0 0.3 17.1 3.0 1.3 1.7 1.4 0.6 3.4 0.8 0.4 0.5 0.3 0.7 0.1 2.1 3.5 0.5 1.4 1.1 1.7 0.0 0.0 1.9 0.0 0.0 0.0 0.0 3.5 0.2 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.7 0.1 0.0 0.1 14.3 27.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 6.1 0.0 0.0 0.3 7.1 0.4 0.0 70.6 0.2 5.0 0.0 5.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.7 1.2 0.7 1.2 0.4 0.6 1.0 0.7 0.9 0.8 0.7 1.7 4.4 0.0 0.0 2.9 1.0 0.6 0.1 0.4 0.0 7.5 0.2 0.3 1.0 0.0 0.0 11.0 6.2 2.2 0.2 0.1 15.6 0.0 0.8 1.0 1.4 5.9 0.0 0.0 30.0 0.0 0.8 9.2 0.0 3.0 0.0 0.6 2.5 0.1 0.2 0.0 21.1 0.0 0.0 0.0 0.5 0.7 0.3 1.3 0.0 6.5 0.1 4.5 0.0 7.1 28.4 0.1 0.0 1.2 0.3 0.1 0.0 164.0 0.0 27.1 0.0 1.2 1.0 0.6 0.7 0.1 0.3 2.5 1.1 0.1 0.0 0.1 NPHS1 "CNF, NPHN" ENSG00000161270 "NPHS1 adhesion molecule, nephrin" O60500 19 35825372-35869287 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Myogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "kidney: 41.5;pancreas: 22.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 5.0;Early spermatids: 13.5;Endometrial ciliated cells: 4.5;Fibroblasts: 5.1;Glandular and luminal cells: 12.1;Late spermatids: 6.9" "Cancer enhanced" "Detected in some" "pancreatic cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 1.1;JURKAT: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB035555 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "CAB035555: " "unprognostic (3.42e-2)" "unprognostic (1.53e-1)" "unprognostic (1.96e-1)" "unprognostic (3.53e-2)" "unprognostic (1.65e-1)" "unprognostic (2.39e-2)" "unprognostic (6.47e-3)" "unprognostic (2.25e-2)" "unprognostic (1.58e-1)" "unprognostic (1.69e-1)" "unprognostic (3.32e-2)" "unprognostic (3.17e-1)" "unprognostic (3.83e-5)" "unprognostic (4.30e-2)" "unprognostic (4.38e-2)" "unprognostic (1.20e-1)" "unprognostic (2.05e-1)" 0.3 0.0 0.4 0.6 0.9 0.2 0.0 0.8 0.4 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.2 41.5 0.1 0.0 3.9 0.4 0.4 0.0 22.8 0.0 0.1 0.0 0.5 0.0 0.0 0.7 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.3 0.7 0.6 0.7 0.0 0.0 2.2 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.8 0.4 0.4 0.2 0.4 0.4 0.5 0.1 0.6 0.7 0.3 0.0 0.5 0.0 0.2 0.8 0.8 0.0 0.6 5.0 0.3 0.3 1.0 0.0 0.0 3.7 0.0 0.0 0.2 0.0 0.0 0.3 13.5 4.5 0.4 0.7 0.0 0.0 0.7 2.4 0.0 5.1 0.0 12.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 2.1 6.9 0.0 2.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 1.2 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.1 0.0 0.4 0.5 0.8 0.4 0.1 0.4 0.0 0.3 0.0 0.1 0.3 NPHS2 "PDCN, SRN1" ENSG00000116218 "NPHS2 stomatin family member, podocin" Q9NP85 1 179550539-179575952 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 140 "kidney: 255.0" "Group enriched" "Detected in some" 7 "Collecting duct cells: 20.2;Early spermatids: 9.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 12 "NTERA-2: 1.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB037267, HPA049486" Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 29: Early spermatids - Spermatogenesis" "CAB037267: AB_261982, HPA049486: AB_2680788" "unprognostic (6.77e-2)" "unprognostic (9.71e-2)" "unprognostic (1.86e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 255.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.2 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 NPL "C1orf13, DHDPS1, NPL1" ENSG00000135838 "N-acetylneuraminate pyruvate lyase" Q9BXD5 1 182789293-182830384 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 52.3;placenta: 45.2" "Cell type enhanced" "Detected in many" "Astrocytes: 170.1;Cytotrophoblasts: 123.1;Hofbauer cells: 481.5;Kupffer cells: 148.8;Microglial cells: 125.5;Proximal tubular cells: 141.0;Syncytiotrophoblasts: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 423.2" "Group enriched" "Detected in many" 34 "granulocytes: 423.2;monocytes: 128.4" "Cell line enhanced" "Detected in many" "HEL: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028345, HPA075808" Enhanced Approved "Vesicles,Plasma membrane" NA NA 190000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Plasma membrane" "HPA028345: AB_10610145, HPA075808: " "unprognostic (2.43e-2)" "unprognostic (5.71e-3)" "unprognostic (1.72e-2)" "unprognostic (1.06e-1)" "unprognostic (1.57e-1)" "unprognostic (3.06e-1)" "prognostic unfavorable (8.05e-4)" "unprognostic (4.41e-2)" "unprognostic (6.54e-3)" "unprognostic (1.45e-1)" "unprognostic (1.49e-1)" "unprognostic (6.18e-2)" "prognostic unfavorable (6.63e-4)" "unprognostic (2.11e-1)" "unprognostic (2.93e-2)" "unprognostic (2.35e-2)" "unprognostic (7.44e-2)" 12.7 5.8 16.7 19.2 20.8 18.9 5.5 19.3 22.9 4.3 11.1 6.9 2.8 1.7 29.9 10.0 3.3 13.0 2.6 12.7 15.6 52.3 20.8 14.5 32.5 19.6 20.1 1.4 2.8 3.3 1.7 45.2 18.9 2.3 9.1 1.9 4.2 6.2 1.7 8.4 4.4 7.5 15.8 28.7 5.0 5.1 27.0 6.2 2.6 2.8 14.7 15.5 5.1 22.0 3.4 0.6 1.0 0.0 2.8 2.8 0.9 1.1 2.1 1.2 0.6 0.0 1.4 9.0 1.5 0.0 0.0 1.3 1.9 2.4 0.3 0.0 1.5 14.2 0.4 0.1 1.5 5.4 8.1 2.2 9.1 0.2 0.0 0.1 0.1 10.1 10.9 13.8 2.1 1.1 0.3 3.5 11.0 7.0 1.1 1.4 0.7 11.0 0.2 7.4 3.1 4.6 5.0 0.3 4.7 1.1 2.9 8.7 0.2 1.1 2.4 0.7 0.1 9.8 12.7 9.0 2.4 9.5 3.6 25.5 128.4 104.1 5.5 118.2 4.8 1.8 4.5 4.9 7.6 6.3 3.5 4.9 423.2 0.3 96.6 1.5 8.1 65.4 16.7 20.8 19.3 22.9 12.7 15.6 19.6 20.1 18.9 15.8 27.0 22.0 2.9 0.0 5.5 170.1 4.9 6.1 4.0 8.6 1.8 7.6 1.5 4.4 2.9 2.8 4.8 7.3 2.1 123.1 2.2 2.3 19.6 1.2 19.1 0.4 0.6 3.5 1.8 45.5 7.5 2.4 6.1 2.5 3.1 0.2 5.7 0.5 72.8 3.9 481.5 6.7 13.5 1.4 6.1 148.8 11.5 27.0 0.9 91.7 10.6 125.5 40.1 2.8 5.2 22.1 21.0 1.3 0.3 0.4 0.7 1.6 0.9 141.0 1.7 2.8 0.0 1.7 1.7 16.5 8.9 16.5 7.1 107.4 3.1 3.4 1.6 4.3 NQO2 "DHQV, DIA6, NMOR2, QR2" ENSG00000124588 "N-ribosyldihydronicotinamide:quinone reductase 2" P16083 6 2987987-3019755 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 202.5;Proximal tubular cells: 730.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 240.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021283, HPA021332" Enhanced Supported Nucleoplasm,Cytosol NA NA 6000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA021283: AB_1854600, HPA021332: AB_1854601" "unprognostic (7.11e-3)" "unprognostic (1.43e-3)" "unprognostic (2.41e-1)" "unprognostic (3.01e-2)" "unprognostic (1.00e-2)" "unprognostic (3.58e-1)" "prognostic unfavorable (8.40e-4)" "unprognostic (1.77e-1)" "unprognostic (1.15e-1)" "unprognostic (4.90e-2)" "unprognostic (6.59e-2)" "unprognostic (3.60e-2)" "unprognostic (8.28e-2)" "unprognostic (2.03e-1)" "unprognostic (3.32e-2)" "unprognostic (3.96e-1)" "unprognostic (2.02e-1)" 60.0 121.5 48.1 27.0 48.8 72.1 45.0 61.1 65.4 32.6 64.3 28.2 35.3 25.8 32.9 32.8 30.0 31.5 76.5 48.5 49.6 190.3 124.2 30.4 19.5 61.8 47.9 29.8 42.6 33.5 21.2 28.6 61.4 28.1 19.6 31.1 61.9 28.9 123.6 50.7 35.6 19.8 42.9 39.3 36.1 18.2 51.5 18.3 26.8 144.9 18.2 31.8 29.0 53.2 45.7 75.7 42.1 95.3 73.0 42.9 45.4 40.5 51.2 37.1 40.9 80.0 16.1 36.9 144.7 71.1 86.4 33.7 45.4 28.5 28.9 95.9 37.1 23.6 83.0 77.3 59.7 24.4 73.9 27.8 34.2 44.9 40.9 53.4 36.8 47.9 142.3 24.1 30.8 95.5 27.0 44.4 54.9 87.6 59.8 49.3 50.1 108.2 56.6 24.0 11.4 15.9 59.5 25.9 128.9 75.0 35.4 16.9 60.7 34.8 14.4 45.9 18.1 45.4 116.7 12.3 43.3 69.5 72.7 25.2 91.8 52.8 33.1 64.2 24.4 12.1 29.6 29.8 61.7 9.1 17.8 19.6 240.2 30.0 60.8 6.5 37.2 43.2 48.1 48.8 61.1 65.4 48.5 49.6 61.8 47.9 61.4 42.9 51.5 53.2 30.3 9.6 16.1 9.8 16.3 35.2 41.5 32.7 12.5 34.8 34.2 32.1 72.8 47.1 21.3 25.8 10.4 42.6 18.2 21.2 162.4 29.1 51.6 15.1 21.4 28.0 4.8 43.8 47.0 63.4 53.9 51.5 33.1 9.0 13.9 11.0 25.7 202.5 76.6 42.1 46.7 23.3 30.5 44.7 105.7 62.8 35.8 75.4 67.6 19.7 148.6 54.0 20.6 10.6 9.1 55.8 18.3 41.0 15.0 38.6 103.7 730.3 28.7 22.5 26.3 35.0 42.9 24.8 11.4 35.4 41.2 31.2 20.8 21.9 25.4 41.8 NR1I3 "CAR, CAR1, MB67" ENSG00000143257 "Nuclear receptor subfamily 1 group I member 3" Q14994 1 161229666-161238244 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "liver: 169.9" "Group enriched" "Detected in some" 4 "Hepatocytes: 134.8;Proximal tubular cells: 47.1" "Cancer enriched" "Detected in single" 67 "liver cancer: 17.6" "Region enhanced" "Detected in some" "basal ganglia: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA051365 Approved Nucleoplasm NA NA "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA051365: AB_2616454" "unprognostic (2.59e-3)" "unprognostic (1.06e-2)" "unprognostic (9.33e-2)" "unprognostic (6.92e-4)" "unprognostic (2.55e-1)" "unprognostic (1.88e-2)" "unprognostic (1.91e-2)" "unprognostic (5.51e-2)" "unprognostic (8.69e-2)" "unprognostic (1.85e-1)" "unprognostic (6.23e-2)" "unprognostic (5.63e-3)" "unprognostic (2.71e-1)" "unprognostic (5.79e-2)" "unprognostic (6.44e-2)" "unprognostic (5.48e-3)" "unprognostic (2.62e-2)" 0.1 0.1 0.2 0.0 2.2 0.6 0.0 0.4 1.0 0.1 0.0 0.1 2.4 0.1 0.0 0.2 0.1 0.0 0.4 0.1 0.0 10.0 169.9 0.2 0.2 0.2 0.1 0.1 0.2 0.0 1.7 0.0 0.3 0.1 0.0 1.0 0.0 0.0 1.5 1.2 3.6 0.0 0.0 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.6 0.1 0.4 0.4 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 3.8 0.1 0.4 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.9 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.5 0.2 0.0 0.3 0.1 0.2 0.7 0.7 0.5 0.4 0.3 0.2 0.0 0.7 0.8 0.6 0.1 1.2 0.1 0.5 0.8 0.5 0.8 0.2 0.3 0.6 0.1 0.6 1.0 0.5 0.2 1.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.2 0.4 1.0 0.1 0.0 0.2 0.1 0.3 0.0 0.2 0.6 0.8 22.4 11.7 0.0 1.3 0.6 1.2 0.1 0.0 0.7 0.2 0.1 0.5 5.7 5.0 3.7 0.0 0.1 0.2 0.2 3.9 0.1 1.7 0.1 0.2 2.3 0.0 8.0 0.4 0.0 0.2 1.9 0.0 0.1 13.3 0.1 3.9 134.8 0.3 0.0 0.6 0.0 0.0 4.1 1.1 3.1 0.3 1.8 0.0 0.0 0.1 0.4 0.0 0.5 0.0 0.1 0.0 0.4 0.8 0.5 5.0 47.1 4.4 1.6 0.0 2.4 0.5 0.2 0.2 0.0 0.0 0.0 1.6 0.1 0.3 0.9 NRK DKFZp686A17109 ENSG00000123572 "Nik related kinase" Q7Z2Y5 X 105822539-105958610 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 16.1;ovary: 32.5;placenta: 24.2" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 79.4;Leydig cells: 113.4;Syncytiotrophoblasts: 67.9;Theca cells: 70.2" "Cancer enriched" "Detected in some" 8 "testis cancer: 6.1" "Region enriched" "Detected in single" 11 "cerebellum: 7.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 58.1;HSkMC: 10.6;RH-30: 12.8;RPTEC TERT1: 34.8;SuSa: 40.5" "Region enriched" "Detected in single" 28 "cerebellum: 14.2" "Region enhanced" "Detected in all" "cerebellum: 41.6" HPA017238 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Cytosol" "HPA017238: AB_1854645" "unprognostic (2.64e-4)" "unprognostic (9.82e-2)" "unprognostic (5.98e-3)" "unprognostic (5.52e-2)" "unprognostic (3.87e-2)" "unprognostic (2.29e-2)" "unprognostic (1.12e-1)" "unprognostic (2.86e-2)" "unprognostic (1.35e-2)" "unprognostic (6.08e-2)" "unprognostic (3.24e-2)" "unprognostic (5.28e-3)" "unprognostic (1.47e-3)" "unprognostic (1.14e-1)" "unprognostic (4.28e-2)" "unprognostic (6.80e-3)" 0.8 16.1 0.0 0.9 0.0 0.0 0.7 7.0 0.3 1.8 0.0 1.4 0.1 1.7 4.6 0.6 0.9 10.1 3.5 0.0 0.1 6.2 0.1 0.2 0.0 0.1 0.6 32.5 0.4 0.1 0.3 24.2 0.5 4.9 0.3 0.1 1.1 0.9 0.2 0.1 0.3 1.7 0.1 0.0 0.5 3.3 0.0 0.1 0.2 3.3 0.0 1.0 0.6 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 10.6 0.0 0.1 0.0 3.5 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 12.8 0.0 34.8 0.7 0.0 0.2 0.0 1.8 0.0 40.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.3 0.0 0.1 0.1 0.6 0.5 0.1 0.0 0.4 3.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.6 0.0 1.2 1.0 4.8 0.0 0.0 0.0 0.0 79.4 0.0 0.2 19.6 0.2 1.3 0.0 3.2 0.7 0.0 0.0 0.9 0.0 10.1 8.9 0.0 0.0 0.0 2.1 0.0 0.0 7.1 0.0 0.9 0.0 0.0 0.0 0.0 2.6 113.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 13.5 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.1 0.7 1.6 1.7 0.1 0.0 67.9 0.0 70.2 0.2 0.1 NTNG1 "KIAA0976, Lmnt1" ENSG00000162631 "Netrin G1" Q9Y2I2 1 107140007-107484923 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 75.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 59.7;Excitatory neurons: 122.1;Inhibitory neurons: 162.5;Oligodendrocyte precursor cells: 425.3" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in all" "thalamus: 75.1" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 48.7;fHDF/TERT166: 25.0;RPTEC TERT1: 27.4;U-138 MG: 21.8;U-251 MG: 16.9;U-87 MG: 24.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "hippocampal formation: 19.7;midbrain: 61.3;pons: 56.0;thalamus: 76.4" HPA065954 Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA065954: AB_2685585" "unprognostic (1.79e-1)" "unprognostic (4.63e-2)" "unprognostic (1.67e-2)" "unprognostic (9.38e-5)" "unprognostic (1.93e-3)" "unprognostic (9.87e-3)" "unprognostic (3.34e-1)" "unprognostic (8.38e-3)" "unprognostic (1.03e-1)" "unprognostic (2.02e-1)" "unprognostic (5.68e-2)" "unprognostic (2.05e-2)" "unprognostic (3.10e-4)" "unprognostic (2.00e-1)" "unprognostic (1.52e-1)" "unprognostic (1.93e-5)" 3.1 4.4 17.2 0.2 3.8 0.0 0.2 6.3 6.7 3.2 0.0 2.2 0.0 0.6 0.0 0.1 0.4 0.6 0.1 7.8 15.2 8.8 0.0 3.8 0.4 5.8 28.3 0.4 0.1 0.1 2.5 1.1 4.6 3.4 0.4 10.3 0.2 4.7 0.0 1.3 0.4 0.1 3.2 0.3 0.2 0.4 75.1 0.5 0.1 0.2 0.6 4.0 1.8 2.7 0.0 0.0 2.8 0.0 5.0 48.7 0.0 13.9 2.1 1.2 1.1 0.0 0.0 0.0 0.6 25.0 0.0 0.0 0.0 1.5 2.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 13.9 0.3 3.5 1.8 14.7 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 1.0 0.0 6.1 0.0 3.1 0.0 27.4 0.0 0.3 0.4 0.0 0.0 0.0 0.8 0.0 0.1 0.2 21.8 4.3 8.1 16.9 0.1 0.0 0.0 24.8 0.0 2.5 0.3 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.0 17.2 3.8 6.3 6.7 7.8 15.2 5.8 28.3 4.6 3.2 75.1 2.7 0.2 0.0 0.0 46.4 3.1 0.5 6.5 0.4 0.0 59.7 0.1 0.0 0.9 0.0 0.2 7.3 0.0 0.1 0.0 0.0 0.0 0.0 10.5 0.1 0.8 0.9 0.0 0.0 122.1 0.0 0.0 2.8 0.0 0.4 0.0 6.1 0.4 0.0 0.0 0.0 162.5 0.0 6.1 0.0 1.3 1.8 8.1 0.0 1.8 18.7 0.0 1.0 0.0 425.3 2.5 0.3 0.0 0.0 1.0 1.1 0.0 0.0 0.0 2.9 6.6 0.2 2.7 0.2 1.1 0.1 0.6 0.0 0.1 7.2 0.0 4.3 NUGGC "C8orf80, HMFN0672, SLIP-GC" ENSG00000189233 "Nuclear GTPase, germinal center associated" Q68CJ6 8 28021964-28083936 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "liver: 20.6;lymphoid tissue: 22.9" "Cell type enhanced" "Detected in some" "Hepatocytes: 15.7;Plasma cells: 35.1;Proximal tubular cells: 7.8" "Cancer enriched" "Detected in many" 5 "liver cancer: 3.8" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 4.0" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Daudi: 116.5;Karpas-707: 38.6;U-698: 84.8" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (6.23e-2)" "unprognostic (2.17e-4)" "unprognostic (1.28e-2)" "unprognostic (1.96e-2)" "unprognostic (2.15e-2)" "unprognostic (1.83e-4)" "unprognostic (2.08e-3)" "unprognostic (6.19e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-3)" "unprognostic (2.45e-1)" "unprognostic (1.95e-1)" "unprognostic (3.39e-3)" "unprognostic (1.84e-1)" "unprognostic (1.33e-1)" "unprognostic (1.69e-1)" "unprognostic (6.14e-2)" 0.4 0.3 1.2 6.2 0.6 0.9 0.8 1.2 1.8 0.1 2.7 1.9 1.9 0.2 0.2 0.4 0.3 0.4 0.2 1.1 1.1 5.1 20.6 0.8 18.7 1.8 1.2 0.5 0.2 0.0 0.0 0.1 1.7 0.3 1.5 0.3 1.3 0.2 0.3 0.5 2.3 0.1 0.1 2.7 2.6 0.4 0.7 0.5 2.1 0.0 22.9 1.6 0.1 3.7 0.1 0.2 0.1 0.2 0.1 0.1 0.3 0.1 0.0 0.0 0.0 1.0 0.3 116.5 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.1 0.2 0.3 1.1 0.0 0.2 0.5 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.5 38.6 0.0 0.1 2.4 0.2 0.1 0.3 0.0 1.1 0.2 0.1 0.0 0.1 0.1 0.3 0.1 0.0 0.1 0.1 0.3 0.6 0.0 0.1 0.3 0.1 0.1 15.2 1.4 84.8 0.2 0.2 0.0 1.0 0.4 0.2 4.0 0.3 0.5 1.6 1.8 2.6 0.1 0.6 0.3 1.0 0.8 0.5 0.1 0.3 0.1 0.5 1.2 0.6 1.2 1.8 1.1 1.1 1.8 1.2 1.7 0.1 0.7 3.7 0.2 0.0 2.2 0.0 5.0 0.3 0.3 0.0 0.0 0.1 0.1 0.0 0.7 0.0 3.7 1.8 0.0 0.0 2.2 0.0 1.9 0.0 1.1 0.1 0.1 0.2 0.0 0.0 0.5 0.0 0.0 0.5 3.1 0.1 1.3 0.0 0.0 15.7 0.0 0.0 0.5 0.0 0.0 0.6 1.1 1.5 0.0 0.4 0.0 0.0 0.1 0.1 2.1 0.5 0.2 0.0 0.0 0.0 35.1 0.2 0.0 7.8 0.0 0.3 0.0 0.4 0.3 0.1 0.0 0.0 1.0 0.0 4.6 0.1 0.0 0.3 NYX "CLRP, CSNB1, CSNB1A, CSNB4" ENSG00000188937 Nyctalopin Q9GZU5 X 41447343-41475710 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 7 "Bipolar cells: 13.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "HDLM-2: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 44: HDLM-2 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (3.27e-2)" "unprognostic (6.72e-2)" "unprognostic (4.21e-2)" "unprognostic (4.10e-4)" "unprognostic (1.83e-1)" "unprognostic (3.96e-2)" "unprognostic (1.80e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.5 0.0 0.0 1.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.6 0.0 0.0 0.0 0.5 1.7 0.0 0.0 0.3 0.0 0.1 0.0 0.0 OCSTAMP "C20orf123, dJ257E24.3" ENSG00000149635 "Osteoclast stimulatory transmembrane protein" Q9BR26 20 46540946-46550654 "Predicted membrane proteins, Transporters" Differentiation "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Langerhans cells: 1.9;Melanocytes: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.1;HMC-1: 2.2;Karpas-707: 1.3;NB-4: 2.5;RPMI-8226: 1.2;U-266/84: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA031116 Uncertain NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA031116: AB_10600758" "unprognostic (2.77e-1)" "unprognostic (3.04e-1)" "unprognostic (8.80e-2)" "unprognostic (5.02e-2)" "unprognostic (2.42e-1)" "unprognostic (2.71e-1)" "unprognostic (2.65e-1)" "unprognostic (9.59e-2)" "unprognostic (2.08e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.8 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.5 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OIT3 "FLJ39116, LZP" ENSG00000138315 "Oncoprotein induced transcript 3" Q8WWZ8 10 72893584-72933036 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "liver: 110.8" "Cell type enriched" "Detected in some" 11 "Hepatic stellate cells: 372.3" "Cancer enriched" "Detected in many" 4 "liver cancer: 4.6" "Region enhanced" "Detected in single" "cerebellum: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CACO-2: 2.3;Hep G2: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 52000000 "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.42e-2)" "unprognostic (6.76e-2)" "unprognostic (7.98e-4)" "unprognostic (9.26e-2)" "unprognostic (9.47e-4)" "unprognostic (3.05e-1)" "unprognostic (4.33e-2)" "unprognostic (1.99e-2)" "unprognostic (1.00e-1)" "unprognostic (1.11e-1)" "unprognostic (8.50e-3)" "unprognostic (1.41e-1)" "unprognostic (4.11e-2)" "unprognostic (1.35e-1)" "unprognostic (2.44e-1)" "unprognostic (3.68e-3)" "unprognostic (1.19e-1)" 0.0 0.0 0.1 0.3 0.1 0.0 0.0 1.3 0.5 0.0 0.1 0.3 5.3 0.0 0.0 0.0 0.0 0.3 2.8 0.1 0.0 1.5 110.8 0.3 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 6.1 0.0 0.0 7.8 0.1 0.5 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.4 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.3 0.5 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.7 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 10.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.2 0.0 14.6 0.0 10.7 0.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 372.3 10.6 0.0 0.0 0.9 0.0 0.0 31.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.4 0.5 0.0 0.0 OSBPL6 ORP6 ENSG00000079156 "Oxysterol binding protein like 6" Q9BZF3 2 178194481-178402893 "Plasma proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 33.8;tongue: 20.3" "Cell type enhanced" "Detected in many" "Astrocytes: 281.4;Excitatory neurons: 314.2;Inhibitory neurons: 404.2;Oligodendrocyte precursor cells: 134.2" "Cancer enhanced" "Detected in many" "glioma: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 48.8;hTERT-HME1: 50.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032131 Enhanced Approved "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA032131: AB_10670963" "unprognostic (6.22e-2)" "unprognostic (1.53e-1)" "unprognostic (2.47e-1)" "unprognostic (5.95e-3)" "unprognostic (5.26e-2)" "unprognostic (1.40e-2)" "unprognostic (7.55e-2)" "unprognostic (4.81e-2)" "unprognostic (3.32e-1)" "unprognostic (1.03e-1)" "unprognostic (3.03e-3)" "unprognostic (3.49e-2)" "unprognostic (1.15e-5)" "unprognostic (1.11e-2)" "unprognostic (1.30e-1)" "unprognostic (3.73e-4)" "unprognostic (4.44e-6)" 1.3 1.5 4.1 1.0 6.1 0.2 1.7 3.7 16.3 1.1 0.0 1.0 0.7 0.8 0.7 2.4 1.0 1.1 3.8 6.1 8.0 2.7 5.6 4.0 1.1 5.7 6.9 1.4 1.2 0.8 6.7 0.6 5.3 3.1 1.0 8.4 2.2 1.5 33.8 8.7 3.5 1.4 1.7 1.0 0.8 1.3 7.5 1.6 2.3 20.3 0.8 1.0 1.5 8.3 0.0 1.1 8.3 16.9 6.8 7.5 6.3 13.9 7.2 12.0 14.6 1.4 0.2 0.0 0.5 12.9 6.6 0.3 19.6 11.4 20.2 0.2 10.2 48.8 2.9 0.0 4.4 8.0 0.3 5.0 17.6 26.4 50.8 4.3 5.8 6.2 0.9 5.8 15.9 7.0 0.1 0.0 10.0 0.0 10.2 0.0 16.9 3.2 0.9 0.0 6.3 3.8 6.2 1.8 13.7 9.2 2.4 0.1 11.4 13.7 8.5 9.3 16.3 31.8 13.4 0.0 16.3 0.0 6.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 4.1 6.1 3.7 16.3 6.1 8.0 5.7 6.9 5.3 1.7 7.5 8.3 0.7 0.0 7.2 281.4 0.0 13.3 2.1 1.3 7.4 59.4 2.1 1.7 15.2 4.3 6.5 0.0 25.0 0.2 0.0 0.1 1.9 0.6 1.0 4.4 1.0 1.7 1.8 0.0 314.2 0.8 4.9 4.3 0.0 0.4 7.0 2.0 0.0 6.2 3.9 1.7 404.2 6.0 4.1 3.5 1.0 1.1 0.0 0.7 5.4 62.8 0.0 10.6 0.0 134.2 10.3 0.2 0.0 1.5 1.5 2.2 9.5 6.2 78.2 6.9 0.0 25.4 5.8 0.1 2.1 6.4 20.9 0.1 0.9 14.5 1.4 0.5 OXT "OT, OT-NPI, OXT-NPI" ENSG00000101405 "Oxytocin/neurophysin I prepropeptide" P01178 20 3071620-3072517 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 60 "brain: 1167.9" "Cell type enhanced" "Detected in many" "Early spermatids: 30.0;Hepatocytes: 41.2;Late spermatids: 66.3;Proximal enterocytes: 15.7;Proximal tubular cells: 36.5" "Cancer enriched" "Detected in some" 5 "testis cancer: 12.1" "Region enriched" "Detected in many" 141 "hypothalamus: 1167.9" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CACO-2: 1.6;HMC-1: 1.1" "Region enriched" "Detected in many" 6 "hypothalamus: 179.3" "Group enriched" "Detected in some" 903 "basal ganglia: 794.6;hypothalamus: 1854.1" HPA071892 Supported Supported "Secreted to blood" NA NA 1500000 "Cluster 49: Eosinophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA071892: AB_2732190" "unprognostic (7.45e-3)" "unprognostic (1.99e-2)" "unprognostic (2.66e-2)" "unprognostic (2.28e-1)" "unprognostic (2.62e-1)" "unprognostic (3.82e-2)" "unprognostic (8.22e-2)" "unprognostic (8.36e-2)" "unprognostic (6.02e-2)" "unprognostic (3.05e-2)" "unprognostic (6.65e-2)" "unprognostic (6.18e-1)" "unprognostic (3.81e-1)" "unprognostic (3.36e-2)" "unprognostic (1.95e-1)" "unprognostic (1.81e-1)" "unprognostic (1.10e-1)" 3.2 1.7 8.3 0.0 0.8 0.1 1.7 0.5 0.9 0.9 0.7 0.4 1.0 0.4 0.0 0.2 0.3 0.0 0.5 0.2 1167.9 4.1 19.3 0.2 0.1 0.2 0.7 0.3 0.1 0.0 15.9 0.0 0.2 0.7 0.0 0.0 0.5 0.1 0.2 2.3 1.0 0.0 1.3 0.2 0.2 2.6 7.8 0.0 0.6 0.0 0.0 0.4 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 3.4 0.4 0.2 0.5 2.1 0.8 0.5 0.4 1.6 1.4 1.7 0.5 0.2 0.0 0.7 1.3 0.3 8.3 0.8 0.5 0.9 0.2 1167.9 0.2 0.7 0.2 1.3 7.8 0.2 0.6 0.0 1.8 0.3 3.5 0.8 0.7 0.1 1.2 0.0 1.2 1.7 0.2 0.0 1.3 5.5 0.0 0.0 2.3 0.1 1.9 0.1 30.0 0.2 2.4 0.3 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.5 0.0 0.3 0.0 41.2 0.2 0.0 0.1 1.8 0.0 0.3 1.6 66.3 0.9 0.6 3.6 0.0 0.0 0.0 1.0 0.5 0.0 0.2 1.7 1.2 1.2 0.4 15.7 36.5 0.9 0.0 0.0 1.8 0.7 1.1 7.8 0.3 1.0 0.0 1.1 0.0 2.0 0.3 PAH PH ENSG00000171759 "Phenylalanine hydroxylase" P00439 12 102836889-102958410 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Phenylalanine catabolism" "Allosteric enzyme, Monooxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets, Phenylketonuria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "kidney: 496.6;liver: 1408.4" "Group enriched" "Detected in some" 6 "Cholangiocytes: 250.2;Hepatocytes: 807.7;Proximal tubular cells: 344.4" "Cancer enriched" "Detected in some" 17 "liver cancer: 94.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 31 "Hep G2: 238.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028407, HPA031642" Enhanced Approved "Endoplasmic reticulum,Vesicles" No NA 40000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Endoplasmic reticulum, Vesicles" "HPA028407: AB_10601241, HPA031642: AB_2673974" "unprognostic (1.16e-1)" "unprognostic (1.52e-1)" "unprognostic (4.47e-2)" "unprognostic (9.13e-3)" "unprognostic (5.19e-2)" "unprognostic (5.99e-2)" "prognostic favorable (4.30e-4)" "unprognostic (1.27e-1)" "unprognostic (6.60e-2)" "unprognostic (4.45e-3)" "unprognostic (1.94e-3)" "unprognostic (1.83e-1)" "unprognostic (1.10e-2)" "unprognostic (3.51e-1)" "unprognostic (1.64e-1)" "unprognostic (3.96e-2)" "unprognostic (1.68e-2)" 0.2 6.4 2.1 0.0 1.9 0.0 0.2 1.8 3.4 0.1 1.1 0.3 0.1 0.1 0.5 0.0 0.1 79.4 0.0 2.2 2.3 496.6 1408.4 0.0 0.1 2.8 2.3 0.1 9.2 0.8 3.0 0.0 2.3 1.5 0.0 2.4 0.1 0.1 0.0 0.0 0.1 0.0 2.6 0.3 0.4 3.3 2.5 0.7 0.6 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.3 238.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.2 1.0 0.1 0.2 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.9 1.8 3.4 2.2 2.3 2.8 2.3 2.3 2.6 2.5 2.8 0.0 0.0 0.0 1.0 2.7 0.0 0.0 0.0 0.0 1.4 0.2 0.1 0.5 250.2 0.0 5.5 0.0 0.0 0.0 0.0 21.5 2.4 66.8 0.0 0.1 1.1 1.8 21.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 807.7 0.0 3.3 2.3 0.0 0.0 22.2 0.0 15.7 0.6 1.8 0.0 0.0 0.0 0.6 0.0 4.5 0.0 0.0 0.0 1.2 0.0 0.4 0.0 344.4 0.0 0.2 0.0 0.0 0.0 2.1 0.4 0.0 0.0 0.0 3.3 0.0 0.0 0.1 PAK5 "KIAA1264, PAK7" ENSG00000101349 "P21 (RAC1) activated kinase 5" Q9P286 20 9537370-9839076 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 12.0;retina: 4.7" "Group enriched" "Detected in some" 4 "Breast myoepithelial cells: 6.5;Glandular and luminal cells: 2.0;Granulosa cells: 5.8" "Cancer enhanced" "Detected in single" "glioma: 0.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "SCLC-21H: 4.6;SH-SY5Y: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020444 Approved Approved Nucleoplasm NA NA "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA020444: AB_1854947" "unprognostic (5.14e-5)" "unprognostic (3.35e-1)" "unprognostic (1.05e-1)" "unprognostic (8.63e-2)" "unprognostic (3.21e-1)" "unprognostic (3.04e-1)" "unprognostic (2.25e-4)" "unprognostic (3.76e-1)" "unprognostic (2.56e-2)" "unprognostic (3.83e-1)" "unprognostic (3.35e-2)" "unprognostic (6.04e-2)" "unprognostic (4.58e-1)" 0.0 1.9 3.6 0.0 4.8 0.0 0.4 12.0 8.4 0.1 0.0 0.0 0.0 0.2 0.6 0.2 0.0 1.2 0.0 5.5 0.7 0.2 0.7 0.0 0.0 0.3 1.4 0.0 1.3 0.0 1.2 0.0 0.4 0.4 0.0 4.7 0.3 0.4 0.0 0.4 0.0 0.0 0.2 0.0 0.3 0.2 2.1 0.4 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 4.8 12.0 8.4 5.5 0.7 0.3 1.4 0.4 0.2 2.1 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.0 0.0 5.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 PBLD "FLJ14767, MAWBP, MAWDBP" ENSG00000108187 "Phenazine biosynthesis like protein domain containing" P30039 10 68282660-68333049 "Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "intestine: 171.5;kidney: 270.0;liver: 335.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 97.5;Distal tubular cells: 109.5;Hepatocytes: 216.9;Proximal enterocytes: 380.2;Proximal tubular cells: 426.5" "Cancer enhanced" "Detected in all" "liver cancer: 16.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA038035, HPA038036" Enhanced Approved Vesicles NA NA 1100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA038035: AB_10672470, HPA038036: AB_10675625" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (6.14e-2)" "unprognostic (8.83e-3)" "unprognostic (1.14e-1)" "unprognostic (2.78e-1)" "prognostic favorable (1.44e-4)" "unprognostic (8.25e-2)" "unprognostic (3.62e-2)" "unprognostic (3.36e-3)" "unprognostic (1.19e-1)" "unprognostic (6.26e-3)" "unprognostic (3.40e-2)" "unprognostic (1.17e-1)" "unprognostic (2.07e-2)" "unprognostic (8.28e-2)" "unprognostic (6.68e-2)" 8.9 11.2 2.9 8.4 5.5 9.3 4.5 5.3 5.3 3.9 4.2 33.2 171.5 5.9 3.8 3.4 7.2 9.4 6.2 3.0 4.6 270.0 335.2 3.9 5.5 4.9 4.1 3.6 63.0 5.6 2.3 4.2 4.2 5.6 27.6 8.7 4.5 5.1 5.6 5.6 146.4 5.0 3.0 4.6 54.8 3.8 4.4 2.1 5.5 3.1 2.2 5.4 2.1 8.9 3.8 7.5 7.1 4.9 6.4 3.6 3.3 15.1 9.5 5.6 5.8 6.9 9.5 4.2 5.6 10.6 2.3 5.8 3.3 3.9 4.8 2.0 5.4 3.3 9.3 6.4 3.0 5.0 3.3 6.4 4.0 3.4 4.2 10.1 3.5 4.0 3.1 9.2 8.9 5.9 4.7 8.7 2.1 3.0 3.2 8.0 9.4 7.1 11.3 5.4 4.1 5.5 10.1 5.8 7.0 2.0 20.0 5.9 10.9 5.5 3.9 2.7 2.5 5.5 4.3 6.3 6.6 2.7 1.4 2.6 2.8 1.5 0.4 1.4 0.8 0.8 0.6 0.4 2.8 0.6 1.1 0.7 3.3 1.8 0.9 1.2 1.1 1.2 2.9 5.5 5.3 5.3 3.0 4.6 4.9 4.1 4.2 3.0 4.4 8.9 1.6 3.2 4.2 3.6 4.5 1.9 1.7 2.2 1.2 5.0 6.2 2.8 3.5 24.3 4.3 55.2 10.4 3.9 3.7 97.5 109.5 8.8 1.2 17.9 5.7 3.4 7.2 6.6 1.8 31.8 2.0 3.2 33.1 6.5 1.3 8.2 6.4 216.9 3.1 10.1 2.8 42.6 2.0 10.4 4.4 0.4 4.1 5.5 1.8 3.7 5.0 5.5 3.1 3.0 7.5 12.5 46.4 3.0 1.5 2.0 380.2 426.5 12.9 17.2 0.0 2.0 6.6 1.6 1.4 1.8 0.6 3.1 2.8 9.6 57.3 3.0 PC PCB ENSG00000173599 "Pyruvate carboxylase" P11498 11 66848417-66958386 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Lipid biosynthesis, Lipid metabolism" "Ligase, Multifunctional enzyme" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 148.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 201.9;Late spermatids: 53.2" "Cancer enhanced" "Detected in all" "liver cancer: 37.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 57.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033742, HPA043922, HPA058765" Enhanced Enhanced Mitochondria Yes No 200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 15: Hepatocytes - Hemostasis" Mitochondria "CAB033742: AB_2283532, HPA043922: AB_2678732, HPA058765: AB_2683812" "unprognostic (2.10e-1)" "unprognostic (1.51e-1)" "unprognostic (1.36e-2)" "unprognostic (8.24e-3)" "unprognostic (3.67e-1)" "unprognostic (3.18e-2)" "unprognostic (2.97e-1)" "unprognostic (3.00e-1)" "unprognostic (3.63e-1)" "prognostic unfavorable (7.86e-5)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "prognostic favorable (8.22e-5)" "unprognostic (8.58e-3)" "unprognostic (5.67e-2)" "unprognostic (9.15e-3)" "unprognostic (1.05e-1)" 60.9 23.7 35.7 2.9 35.5 3.5 28.4 36.6 35.8 3.7 17.5 4.7 6.5 3.8 1.8 9.3 3.2 2.8 4.3 32.4 41.0 23.3 148.0 2.6 1.3 43.4 40.1 5.1 4.9 18.2 8.6 4.4 37.6 7.2 2.8 2.4 35.3 9.3 12.1 4.7 7.7 1.4 37.8 1.5 9.1 10.7 49.0 2.0 4.6 6.6 2.0 2.9 4.4 37.0 6.1 19.3 6.5 17.2 25.4 8.9 6.6 3.4 15.5 6.9 7.5 8.8 6.0 0.0 7.4 6.0 9.6 6.8 7.7 39.5 1.5 2.8 11.0 10.3 57.4 41.2 21.0 0.1 10.8 40.2 10.1 5.8 12.4 4.4 5.7 14.3 17.4 0.0 2.1 44.6 9.2 4.6 12.0 15.1 16.2 8.3 13.0 3.2 5.7 1.9 15.2 21.0 33.6 18.0 15.5 4.8 14.6 2.7 6.3 7.8 6.6 8.8 4.7 3.5 4.8 0.1 7.7 5.7 6.7 0.0 1.3 0.0 0.5 0.3 0.5 0.0 0.1 0.5 0.9 0.2 0.9 0.5 0.1 0.1 0.1 0.3 0.5 0.7 35.7 35.5 36.6 35.8 32.4 41.0 43.4 40.1 37.6 37.8 49.0 37.0 0.9 0.0 3.0 26.4 1.4 1.3 1.6 9.1 2.8 5.6 4.8 5.8 4.4 11.5 3.0 3.7 2.1 17.4 0.6 27.6 1.9 3.1 18.4 2.3 7.1 1.5 9.0 28.0 18.5 1.8 4.2 3.2 5.6 3.0 8.9 16.0 4.6 201.9 12.3 0.0 18.6 5.0 0.0 7.0 1.8 53.2 0.6 1.8 5.4 7.5 18.9 9.4 2.1 10.1 16.7 2.3 8.5 4.1 0.1 3.1 23.6 39.0 1.5 4.8 0.0 2.2 2.2 11.2 4.7 4.1 0.6 25.4 1.2 6.0 6.4 1.3 PCARE "C2orf71, FLJ34931, RP54" ENSG00000179270 "Photoreceptor cilium actin regulator" A6NGG8 2 29060976-29074523 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Ciliopathy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "retina: 28.5" "Cell type enriched" "Detected in single" 20 "Cardiomyocytes: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (2.28e-3)" "unprognostic (1.23e-1)" "unprognostic (1.13e-1)" "unprognostic (3.15e-1)" "unprognostic (1.88e-1)" "unprognostic (5.88e-3)" "unprognostic (6.68e-3)" "unprognostic (1.21e-1)" "unprognostic (6.61e-2)" "unprognostic (3.81e-2)" "unprognostic (2.37e-1)" "unprognostic (2.08e-1)" "unprognostic (1.64e-1)" "unprognostic (2.28e-4)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.5 0.4 0.0 0.1 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 28.5 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.5 0.2 0.3 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDH15 "CDHR15, DFNB23, USH1F" ENSG00000150275 "Protocadherin related 15" Q96QU1 10 53802771-55627942 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Hearing" "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 19.0;brain: 21.2;retina: 61.7" "Cell type enriched" "Detected in some" 13 "Oligodendrocyte precursor cells: 2965.2" "Cancer enriched" "Detected in single" 9 "glioma: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "U-2 OS: 1.1;U-266/70: 3.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA074437 Supported "Intracellular and membrane" NA NA 22000 "Cluster 77: Retina - Visual perception" "Cluster 29: U-266 - Adaptive immune response" "Cluster 68: Oligodendrocytes - Mixed function" "HPA074437: " "unprognostic (1.38e-1)" "unprognostic (3.39e-1)" "unprognostic (8.15e-5)" "unprognostic (3.07e-3)" "unprognostic (2.79e-1)" "unprognostic (9.15e-4)" "unprognostic (2.02e-1)" "unprognostic (3.89e-2)" "unprognostic (1.12e-3)" "unprognostic (1.31e-3)" "unprognostic (1.19e-1)" "unprognostic (1.34e-1)" "unprognostic (3.27e-1)" "unprognostic (7.66e-3)" 0.2 19.0 13.4 0.3 9.5 0.1 0.0 3.1 10.3 0.2 0.0 0.1 0.2 0.1 0.5 0.1 0.1 0.1 0.5 16.6 19.6 8.0 0.0 2.5 0.4 13.8 13.7 0.0 0.0 0.5 4.7 0.2 12.6 0.2 0.0 61.7 0.1 0.0 0.0 0.1 0.2 0.0 9.7 0.7 0.3 3.3 21.2 0.1 0.0 0.0 0.5 0.5 0.0 6.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 1.1 0.0 0.0 3.3 0.3 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 9.5 3.1 10.3 16.6 19.6 13.8 13.7 12.6 9.7 21.2 6.2 0.0 0.0 0.0 14.4 0.0 0.3 0.0 0.0 0.0 5.1 0.6 0.0 4.8 0.0 0.0 0.0 87.6 0.0 0.0 0.0 0.0 0.0 26.1 0.0 0.1 0.3 0.0 0.0 27.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 216.2 0.1 0.0 0.0 0.0 7.5 0.0 0.1 0.0 3.7 0.0 4.4 0.0 2965.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 92.8 0.0 0.0 0.2 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 PCK1 PEPCK-C ENSG00000124253 "Phosphoenolpyruvate carboxykinase 1" P35558 20 57561080-57568121 "Citric acid cycle related proteins, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Gluconeogenesis "Decarboxylase, Kinase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 432.1;liver: 681.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 703.8;Distal tubular cells: 588.9;Hepatocytes: 1184.0;Proximal enterocytes: 2209.9;Proximal tubular cells: 3547.9" "Cancer enriched" "Detected in many" 5 "liver cancer: 99.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "ASC diff: 20.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006277, HPA006507, CAB017027" Approved NA NA 840000 "Cluster 81: Kidney & Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB017027: , HPA006277: AB_1079579, HPA006507: AB_1079578" "unprognostic (3.50e-2)" "unprognostic (5.60e-2)" "unprognostic (4.60e-2)" "unprognostic (8.62e-3)" "unprognostic (1.99e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-2)" "unprognostic (4.43e-2)" "unprognostic (1.84e-1)" "unprognostic (2.37e-1)" "unprognostic (1.64e-1)" "prognostic favorable (1.47e-5)" "unprognostic (1.03e-1)" "unprognostic (6.40e-2)" "unprognostic (1.05e-3)" "unprognostic (2.21e-1)" 59.2 1.1 0.8 1.7 0.8 0.0 29.8 0.7 1.6 0.0 0.6 57.8 110.4 1.2 0.2 0.4 0.9 5.0 1.0 0.7 1.4 432.1 681.4 0.2 0.3 0.7 0.9 1.6 0.4 0.0 21.1 0.3 0.8 0.2 79.8 0.5 1.1 0.2 0.4 0.9 143.9 2.9 0.6 0.3 0.9 0.0 1.3 0.1 0.8 6.5 0.0 0.8 0.1 0.8 0.0 0.0 0.0 0.0 20.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.7 1.6 0.7 1.4 0.7 0.9 0.8 0.6 1.3 0.8 0.7 0.0 0.0 0.0 21.3 0.1 0.0 0.0 15.9 0.3 0.7 0.6 1.0 61.5 0.6 90.1 0.0 0.1 0.1 703.8 588.9 0.6 0.1 1.3 1.5 2.7 53.9 40.2 0.0 0.0 0.0 2.3 19.9 8.5 8.9 0.1 29.6 1184.0 0.0 3.3 0.0 293.6 0.0 22.6 0.0 0.0 0.0 12.8 0.0 1.9 0.0 9.9 0.0 0.0 0.0 0.1 285.5 0.0 0.0 0.0 2209.9 3547.9 0.0 0.4 0.0 0.3 6.0 0.0 0.1 10.3 0.3 0.3 10.2 1.5 348.5 0.1 PCK2 "PEPCK, PEPCK2" ENSG00000100889 "Phosphoenolpyruvate carboxykinase 2, mitochondrial" Q16822 14 24094053-24110598 "Citric acid cycle related proteins, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Gluconeogenesis "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "intestine: 196.1;kidney: 99.1;liver: 374.1" "Group enriched" "Detected in many" 4 "Hepatocytes: 309.3;Proximal enterocytes: 752.6;Proximal tubular cells: 237.1" "Cancer enhanced" "Detected in all" "liver cancer: 91.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 104.7;hTCEpi: 104.7;SK-MEL-30: 103.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB018734, HPA051162, HPA053502" Enhanced Enhanced Mitochondria NA NA 3500000 "Cluster 51: Monocytes - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB018734: AB_2160168, HPA051162: AB_2681368, HPA053502: AB_2682171" "unprognostic (3.38e-2)" "unprognostic (1.13e-1)" "unprognostic (1.50e-2)" "unprognostic (4.07e-1)" "unprognostic (3.11e-1)" "unprognostic (2.10e-1)" "prognostic favorable (2.81e-4)" "unprognostic (3.91e-2)" "unprognostic (1.04e-1)" "unprognostic (2.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.67e-2)" "unprognostic (1.33e-2)" "unprognostic (2.81e-1)" "unprognostic (3.71e-1)" "unprognostic (2.82e-2)" "unprognostic (1.17e-1)" 25.5 10.7 3.2 8.0 3.9 4.5 21.1 3.8 3.3 6.8 3.4 44.8 196.1 5.8 3.1 20.0 5.9 4.5 5.8 3.1 3.9 99.1 374.1 16.5 8.7 4.6 4.2 3.0 34.8 17.4 8.0 2.8 4.1 9.1 19.2 2.7 18.6 7.1 2.6 12.6 136.3 3.8 4.0 21.7 16.0 19.7 3.9 3.7 18.9 1.2 7.5 10.8 10.0 4.3 17.6 9.8 2.7 18.1 11.0 10.5 46.0 21.5 25.6 17.4 28.4 16.1 19.9 44.6 2.6 33.4 5.6 25.4 18.0 28.1 13.8 22.8 0.8 8.0 5.0 84.2 104.7 15.8 33.4 12.9 104.7 10.6 26.5 5.0 14.0 50.6 23.4 79.3 6.4 74.6 4.0 7.6 3.1 39.4 13.0 8.7 10.5 26.0 5.3 26.7 11.3 18.2 16.5 21.2 103.9 2.6 28.5 24.1 2.7 3.8 19.7 5.6 6.0 53.2 18.6 11.0 10.6 24.5 9.6 0.3 11.6 3.5 4.0 21.6 4.1 11.4 4.5 4.5 15.3 7.3 2.7 2.5 1.3 2.2 22.0 2.5 9.1 6.1 3.2 3.9 3.8 3.3 3.1 3.9 4.6 4.2 4.1 4.0 3.9 4.3 4.8 12.8 28.5 1.3 17.9 3.3 10.2 12.3 5.7 4.7 8.6 5.2 1.8 18.6 8.0 18.4 0.0 4.7 4.3 91.2 35.2 18.9 60.1 1.6 5.2 5.6 9.1 24.4 0.5 76.3 14.3 7.4 16.8 4.5 1.3 1.6 13.2 309.3 63.8 0.0 0.9 60.8 18.3 25.8 5.7 30.8 3.4 16.4 7.2 1.0 22.9 5.8 7.2 0.0 0.1 29.0 87.8 3.0 13.3 7.6 752.6 237.1 4.8 5.5 0.0 3.4 18.7 19.8 1.0 9.1 4.8 3.0 7.6 6.8 72.0 15.0 PDZD3 "FLJ22756, IKEPP, PDZK2" ENSG00000172367 "PDZ domain containing 3" Q86UT5 11 119185457-119190223 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 19.3;kidney: 17.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 93.4;Gastric mucus-secreting cells: 30.5;Paneth cells: 74.8;Proximal enterocytes: 79.1;Proximal tubular cells: 29.5;Undifferentiated cells: 21.0" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.3;renal cancer: 2.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "OE19: 1.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA077887 Enhanced NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA077887: " "unprognostic (2.42e-2)" "unprognostic (1.51e-1)" "unprognostic (2.65e-1)" "unprognostic (5.51e-2)" "unprognostic (1.59e-1)" "unprognostic (5.39e-2)" "unprognostic (6.07e-2)" "unprognostic (3.22e-1)" "unprognostic (1.86e-2)" "unprognostic (6.58e-3)" "unprognostic (9.00e-2)" "unprognostic (6.08e-2)" "unprognostic (8.72e-2)" "unprognostic (1.08e-1)" "unprognostic (3.37e-1)" "unprognostic (1.38e-1)" "unprognostic (3.41e-3)" 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.3 17.1 0.0 0.0 0.0 1.0 2.8 0.1 0.0 0.0 17.4 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 19.3 0.1 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 1.0 0.1 0.0 0.1 0.0 0.0 0.1 0.4 0.3 8.6 0.0 0.0 6.2 0.0 0.0 93.4 3.9 0.1 0.0 0.2 0.1 0.2 1.2 0.0 0.0 0.2 0.0 0.4 30.5 0.1 0.0 0.1 1.1 0.1 0.2 0.0 0.0 8.5 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 74.8 0.0 0.2 0.1 79.1 29.5 0.7 0.7 0.0 0.5 0.1 0.0 0.0 0.3 0.1 0.0 0.2 0.1 21.0 0.1 PDZK1 "NHERF3, PDZD1" ENSG00000174827 "PDZ domain containing 1" Q5T2W1 1 145670852-145708148 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 595.8" "Group enriched" "Detected in many" 5 "Proximal enterocytes: 280.0;Proximal tubular cells: 1113.8" "Group enriched" "Detected in many" 4 "liver cancer: 27.6;renal cancer: 44.3" "Region enriched" "Detected in many" 7 "cerebellum: 14.7" "Immune cell enriched" "Detected in single" 5 "NK-cell: 4.2" "Lineage enriched" "Detected in single" 5 "NK-cells: 4.2" "Group enriched" "Detected in many" 4 "RPTEC TERT1: 250.0;T-47d: 653.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA005755, HPA006155, CAB008971" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Vesicles" Cytosol "CAB008971: , HPA005755: AB_1855164, HPA006155: AB_1855163" "unprognostic (4.56e-3)" "unprognostic (3.07e-1)" "unprognostic (8.79e-2)" "unprognostic (4.41e-2)" "unprognostic (9.15e-2)" "unprognostic (2.09e-1)" "unprognostic (2.18e-1)" "unprognostic (3.42e-1)" "unprognostic (2.08e-1)" "unprognostic (3.27e-1)" "unprognostic (2.34e-2)" "unprognostic (9.87e-3)" "prognostic favorable (2.54e-7)" "unprognostic (9.90e-2)" "unprognostic (3.02e-1)" "unprognostic (1.00e-3)" "unprognostic (8.87e-2)" 0.6 3.5 0.7 0.5 0.9 0.6 19.6 14.7 2.0 2.4 1.9 4.7 74.8 0.7 15.8 0.2 1.0 22.0 0.4 1.0 0.5 595.8 128.1 0.3 0.7 1.4 0.8 0.3 16.6 0.0 0.6 0.5 1.8 0.3 8.2 3.0 0.4 0.8 0.3 2.6 124.9 0.8 0.4 0.7 2.8 0.6 0.8 0.3 0.3 0.1 0.2 0.2 0.3 1.5 7.6 1.2 0.8 0.8 0.3 0.4 3.0 1.2 0.3 0.2 1.0 106.6 1.0 0.7 1.3 5.9 0.5 3.4 0.2 0.6 0.6 10.3 2.0 0.9 2.8 45.7 0.0 1.1 0.9 0.3 0.7 0.4 0.2 0.8 0.0 0.4 0.8 1.6 0.8 6.0 0.7 1.4 1.2 1.5 3.6 0.4 7.3 1.6 250.0 0.3 0.6 6.7 1.7 1.8 0.2 6.4 653.8 0.9 0.5 1.3 1.3 0.9 1.1 8.8 1.2 0.6 1.0 0.6 0.5 0.1 0.1 0.0 0.7 0.1 0.2 0.6 0.2 0.8 0.0 0.4 0.2 0.3 0.1 4.2 0.0 0.5 0.0 0.3 0.7 0.9 14.7 2.0 1.0 0.5 1.4 0.8 1.8 0.4 0.8 1.5 0.2 0.0 0.0 2.0 4.1 0.1 0.0 0.1 0.0 0.4 20.2 3.3 0.5 72.9 0.0 57.0 0.0 0.0 0.9 27.4 138.9 1.2 8.6 1.1 0.5 0.4 6.6 0.0 2.8 2.0 0.1 0.5 0.5 4.9 0.0 0.2 1.1 47.9 0.2 0.0 1.9 7.8 0.0 0.9 0.3 9.0 0.0 4.9 0.0 1.9 0.0 0.3 2.1 3.0 0.7 1.5 7.4 0.0 0.0 0.1 280.0 1113.8 0.1 0.5 0.0 0.1 0.3 0.2 0.3 0.0 0.0 0.1 4.1 4.3 6.5 0.1 PDZK1IP1 "DD96, MAP17, SPAP" ENSG00000162366 "PDZK1 interacting protein 1" Q13113 1 47183582-47191044 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 1047.0" "Cell type enriched" "Detected in many" 4 "Proximal tubular cells: 5516.6" "Cancer enhanced" "Detected in all" "renal cancer: 340.7" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "neutrophil: 6.6" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 6 "EFO-21: 148.8;RPTEC TERT1: 501.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA014907 Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "Nuclear speckles" "HPA014907: AB_1855166" "unprognostic (2.97e-1)" "unprognostic (3.33e-2)" "unprognostic (1.03e-1)" "unprognostic (9.16e-2)" "prognostic unfavorable (6.92e-4)" "unprognostic (8.14e-3)" "unprognostic (2.32e-1)" "unprognostic (1.46e-1)" "unprognostic (2.65e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (3.45e-4)" "unprognostic (2.64e-2)" "unprognostic (7.90e-3)" "unprognostic (1.22e-1)" "unprognostic (2.07e-1)" "unprognostic (1.75e-3)" "unprognostic (1.89e-1)" 20.9 8.2 0.6 24.6 0.8 43.2 36.4 0.4 1.2 29.9 0.7 44.4 21.6 10.7 2.9 205.9 25.7 197.6 1.4 0.5 0.7 1047.0 6.8 29.5 0.4 0.4 0.5 0.7 99.9 0.0 1.1 3.9 0.7 12.1 30.9 0.0 203.4 8.6 1.6 153.1 66.4 3.1 0.4 3.7 63.4 1.4 0.9 1.9 1.5 0.6 60.2 20.0 66.6 0.4 54.8 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 41.5 0.0 148.8 0.0 0.0 0.7 0.0 0.5 0.0 0.6 0.0 0.6 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 2.9 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 2.6 501.3 0.0 0.0 0.0 0.5 4.3 0.0 0.0 1.4 0.0 0.0 0.1 1.2 0.1 0.4 0.3 0.6 0.3 0.1 0.1 0.0 0.0 3.4 0.3 0.6 1.1 0.2 0.0 0.0 0.0 1.7 0.4 0.2 0.0 6.6 0.7 0.1 1.5 1.1 144.5 0.6 0.8 0.4 1.2 0.5 0.7 0.4 0.5 0.7 0.4 0.9 0.4 1.6 76.9 47.4 0.0 31.2 14.1 13.3 489.8 7.4 0.0 152.9 105.5 0.1 303.1 413.3 233.6 0.0 0.1 1.7 118.8 414.8 1175.8 0.0 6.1 3.3 4.5 39.6 148.4 0.0 760.0 0.0 6.6 36.7 38.1 10.8 0.2 5.0 1.7 0.3 0.0 0.0 143.3 52.9 0.3 2.1 0.0 3.4 59.3 8.8 0.0 13.6 0.6 2.1 0.0 0.0 1115.2 91.0 0.0 0.1 38.9 106.2 5516.6 147.6 0.0 0.0 0.1 28.7 0.0 0.1 30.7 54.0 0.8 22.0 0.0 150.5 68.5 PEPD ENSG00000124299 "Peptidase D" P12955 19 33386950-33521791 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Collagen degradation" "Dipeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 209.5;kidney: 277.7" "Group enriched" "Detected in all" 4 "Proximal enterocytes: 833.0;Proximal tubular cells: 1278.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015599, HPA072045" Enhanced Approved Nucleoplasm NA NA 860000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA015599: AB_1855192, HPA072045: AB_2732194" "unprognostic (1.39e-1)" "unprognostic (2.62e-2)" "unprognostic (2.27e-1)" "unprognostic (4.01e-2)" "unprognostic (2.98e-1)" "unprognostic (6.77e-2)" "unprognostic (2.82e-1)" "unprognostic (3.64e-2)" "unprognostic (3.96e-1)" "unprognostic (5.10e-2)" "unprognostic (1.11e-2)" "unprognostic (1.99e-1)" "prognostic favorable (6.50e-9)" "unprognostic (4.38e-2)" "unprognostic (1.99e-1)" "unprognostic (1.65e-1)" "unprognostic (1.29e-1)" 53.2 56.0 28.5 26.9 35.5 14.3 43.6 35.6 30.5 36.9 33.5 44.2 180.5 49.7 9.9 42.8 34.2 31.2 24.3 28.7 30.9 277.7 117.8 38.1 30.7 36.2 30.8 35.9 27.1 29.3 42.5 21.9 36.3 23.6 14.8 11.8 33.6 22.9 35.6 43.1 209.5 24.5 34.6 38.2 33.6 18.3 33.4 20.8 37.0 23.2 21.3 40.1 28.2 43.4 43.2 118.7 26.4 53.1 114.9 44.9 80.6 37.4 65.3 45.6 52.7 104.7 34.2 18.8 53.5 73.2 33.9 11.2 39.5 28.5 23.4 51.3 50.4 107.7 24.6 108.3 91.6 29.6 128.8 63.6 29.0 38.2 18.3 27.8 56.4 34.4 22.7 49.4 44.2 54.3 19.0 11.7 46.2 79.6 48.8 45.3 41.0 51.2 39.4 108.8 40.3 106.4 64.2 31.3 62.5 18.2 25.1 36.3 56.6 48.3 46.6 62.3 41.8 45.2 59.1 13.1 49.5 48.2 65.8 113.7 117.2 8.3 75.5 123.6 65.5 49.6 74.0 69.8 100.6 50.5 47.1 55.6 6.1 55.6 92.5 31.0 76.1 119.6 28.5 35.5 35.6 30.5 28.7 30.9 36.2 30.8 36.3 34.6 33.4 43.4 56.9 22.4 27.4 11.4 29.0 19.4 32.9 36.0 11.4 33.3 16.2 24.4 13.3 52.9 23.8 73.5 4.2 21.4 32.6 17.6 197.6 77.2 8.0 15.0 20.1 50.7 17.3 25.4 19.9 44.2 67.3 38.6 18.3 13.0 57.6 41.9 52.8 180.3 227.2 62.2 14.9 35.6 30.5 59.7 40.9 13.2 49.4 75.3 67.6 15.9 102.2 73.6 34.0 21.6 24.3 33.8 79.3 60.5 31.5 22.9 833.0 1278.3 27.1 33.7 39.5 37.0 43.1 10.2 44.5 34.3 20.3 30.4 33.7 48.7 44.6 22.2 PFN3 ENSG00000196570 "Profilin 3" P60673 5 177400109-177400661 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 27 "testis: 25.7" "Group enriched" "Detected in some" 176 "Early spermatids: 666.2;Late spermatids: 1589.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA038274 Approved Vesicles,Cytosol NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Cytosol" "HPA038274: " "unprognostic (1.03e-2)" "unprognostic (1.13e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 666.2 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1589.2 6.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 5.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 PHYHIP "DYRK1AP3, KIAA0273, PAHX-AP" ENSG00000168490 "Phytanoyl-CoA 2-hydroxylase interacting protein" Q92561 8 22219703-22232101 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 217.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 18.9;Basal squamous epithelial cells: 14.8;Excitatory neurons: 48.5;Inhibitory neurons: 15.4" "Cancer enhanced" "Detected in many" "glioma: 6.3;thyroid cancer: 6.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPMI-8226: 9.3;SH-SY5Y: 3.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "amygdala: 101.1;basal ganglia: 300.5;cerebellum: 251.7;cerebral cortex: 256.5;hippocampal formation: 296.8" "HPA068030, HPA069318" Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 25: RPMI-8226 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria Nucleoplasm "HPA068030: AB_2685944, HPA069318: AB_2686117" "unprognostic (1.19e-2)" "unprognostic (2.33e-2)" "unprognostic (3.06e-2)" "unprognostic (9.22e-3)" "unprognostic (2.07e-3)" "unprognostic (2.35e-1)" "unprognostic (1.59e-1)" "unprognostic (2.80e-1)" "unprognostic (3.01e-2)" "unprognostic (7.44e-3)" "unprognostic (2.36e-1)" "unprognostic (4.05e-2)" "unprognostic (4.44e-5)" "unprognostic (8.62e-4)" "unprognostic (1.36e-1)" "unprognostic (1.35e-2)" "unprognostic (4.09e-3)" 11.3 33.1 106.0 1.5 183.9 0.0 9.3 98.1 217.1 11.6 0.0 14.1 1.3 14.5 2.8 9.8 25.6 6.7 5.2 210.3 21.9 9.4 0.7 2.5 0.2 63.7 11.5 7.1 1.6 0.2 35.7 2.5 58.1 11.9 0.6 2.2 1.8 5.9 0.9 55.8 5.1 8.1 2.0 11.5 3.7 10.7 30.7 0.2 3.9 0.3 0.2 12.1 15.1 137.4 0.6 1.6 0.3 0.0 0.2 0.5 0.8 0.2 0.9 0.2 0.2 0.1 1.4 0.0 1.5 0.5 1.0 2.6 0.0 0.4 0.0 0.0 0.1 0.0 3.0 1.0 1.1 0.0 0.0 0.6 0.0 0.6 0.0 2.5 1.7 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.6 0.5 0.2 0.0 0.2 9.3 0.0 0.0 2.9 3.5 2.0 0.0 2.4 0.2 0.0 0.2 0.7 0.0 1.4 1.1 0.5 0.6 0.1 0.0 1.4 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.0 183.9 98.1 217.1 210.3 21.9 63.7 11.5 58.1 2.0 30.7 137.4 1.1 0.0 0.0 7.2 0.0 18.9 5.5 5.6 14.8 1.5 0.7 1.3 1.4 1.5 1.9 3.7 0.0 0.1 0.1 0.2 0.0 0.2 0.8 0.4 3.6 1.5 0.0 0.0 48.5 2.1 0.4 5.6 0.5 0.2 0.0 0.0 1.4 1.0 0.2 0.0 15.4 0.7 0.0 0.0 1.4 1.8 3.1 0.1 1.8 5.6 0.0 0.6 0.0 7.5 5.8 0.8 0.0 3.8 0.0 1.3 2.6 3.5 0.3 1.1 0.0 0.2 8.0 0.4 0.4 8.2 10.9 2.2 0.2 0.1 0.1 5.0 PIPOX LPIPOX ENSG00000179761 "Pipecolic acid and sarcosine oxidase" Q9P0Z9 17 28950513-29057216 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "kidney: 146.0;liver: 506.6" "Group enriched" "Detected in many" 6 "Hepatocytes: 225.4;Proximal tubular cells: 163.7" "Cancer enriched" "Detected in many" 5 "liver cancer: 73.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "AF22: 36.7;Hep G2: 120.2;NTERA-2: 68.4;RH-30: 90.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA 380000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (8.02e-2)" "unprognostic (3.50e-4)" "unprognostic (3.03e-1)" "unprognostic (6.25e-3)" "unprognostic (1.52e-1)" "unprognostic (5.01e-2)" "unprognostic (1.95e-3)" "unprognostic (1.15e-2)" "unprognostic (2.17e-1)" "unprognostic (3.45e-1)" "prognostic favorable (1.49e-4)" "unprognostic (2.39e-1)" "unprognostic (3.13e-3)" "unprognostic (2.58e-3)" "unprognostic (2.01e-1)" "unprognostic (2.79e-2)" "unprognostic (1.22e-1)" 0.4 0.6 14.3 0.6 17.5 0.3 0.3 17.5 15.6 0.7 11.4 3.6 13.6 1.6 24.4 1.8 8.8 3.4 0.4 13.8 15.3 146.0 506.6 1.2 0.9 15.1 16.3 0.9 0.7 1.7 0.8 4.2 14.7 2.0 1.1 4.4 0.5 3.4 0.3 0.7 4.3 2.0 13.0 1.0 0.9 0.3 16.3 0.4 0.2 0.1 0.5 1.3 0.5 14.2 0.0 0.0 36.7 0.3 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.3 0.2 0.8 0.0 0.1 0.2 0.6 0.0 0.1 0.5 0.5 0.5 0.2 120.2 0.0 0.2 0.3 0.0 0.0 0.0 0.2 0.2 0.0 0.4 0.0 1.1 0.0 0.2 0.0 0.7 68.4 2.4 0.0 0.3 90.7 2.2 0.0 0.1 11.2 3.8 0.3 0.2 0.5 5.9 0.2 4.4 0.0 0.1 0.2 0.1 4.3 0.9 11.4 0.4 0.0 0.6 3.6 1.0 0.2 0.3 0.3 0.2 0.3 0.1 0.1 0.4 1.8 0.2 0.1 0.8 1.4 0.3 0.1 0.1 0.4 0.3 14.3 17.5 17.5 15.6 13.8 15.3 15.1 16.3 14.7 13.0 16.3 14.2 0.4 0.0 0.6 12.4 1.4 0.3 0.3 0.2 0.0 2.9 0.2 0.3 0.5 5.7 0.1 0.0 4.2 0.2 0.7 0.2 9.8 0.0 1.5 0.2 0.3 0.8 1.2 5.3 0.2 0.2 7.7 0.7 1.5 0.2 5.7 1.3 5.3 225.4 1.2 0.0 0.5 0.0 0.0 6.0 2.1 2.1 0.3 2.2 0.0 1.0 2.2 29.0 0.0 1.0 0.1 0.0 0.0 1.2 0.2 0.3 1.9 163.7 0.0 1.4 0.0 0.7 0.4 0.1 1.0 0.0 0.1 0.4 1.2 0.1 0.1 0.1 PKLR ENSG00000143627 "Pyruvate kinase L/R" P30613 1 155289293-155301438 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 19.6;kidney: 25.1;liver: 92.5" "Cell type enhanced" "Detected in some" "Early spermatids: 9.3;Erythroid cells: 22.1;Hepatocytes: 16.3;Late spermatids: 23.0;Proximal enterocytes: 14.8;Proximal tubular cells: 48.9" "Cancer enriched" "Detected in some" 9 "liver cancer: 56.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "K-562: 107.8" "Region enhanced" "Detected in single" "basal ganglia: 1.6" "Not detected" "Not detected" "HPA006653, CAB034376, CAB034378" Enhanced Approved Cytosol No NA 5200000 "Cluster 85: Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "CAB034376: AB_2163671, CAB034378: AB_2252321, HPA006653: AB_2667632" "unprognostic (9.16e-2)" "unprognostic (1.22e-1)" "unprognostic (2.22e-1)" "unprognostic (5.98e-2)" "unprognostic (2.62e-1)" "unprognostic (7.86e-4)" "unprognostic (1.53e-2)" "unprognostic (1.08e-1)" "unprognostic (8.79e-2)" "unprognostic (1.89e-1)" "unprognostic (4.07e-1)" "unprognostic (4.53e-2)" "unprognostic (1.96e-2)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" "unprognostic (6.21e-3)" 0.0 0.0 0.0 0.0 0.1 19.6 0.0 0.7 0.1 0.0 0.0 0.4 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 25.1 92.5 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 1.2 7.2 0.0 0.0 0.1 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 11.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.1 0.0 0.5 0.2 0.2 0.3 0.0 0.4 0.0 0.1 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.4 1.5 0.0 1.8 0.0 0.0 0.0 0.6 0.0 0.0 9.3 0.2 0.3 0.1 0.0 22.1 1.2 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.7 16.3 0.2 0.0 1.2 0.9 0.0 0.0 0.0 23.0 0.0 0.3 0.0 1.0 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 14.8 48.9 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 PLA2G12B PLA2G13 ENSG00000138308 "Phospholipase A2 group XIIB" Q9BX93 10 72934762-72954806 "Metabolic proteins, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 33.1;kidney: 14.4;liver: 71.0" "Group enriched" "Detected in some" 4 "Hepatocytes: 52.2;Proximal enterocytes: 70.0" "Cancer enriched" "Detected in many" 8 "liver cancer: 35.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "CACO-2: 9.1;Hep G2: 15.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA057745, HPA059562" Approved "Secreted to blood" NA NA 2300000 "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "HPA057745: AB_2683514, HPA059562: AB_2684064" "unprognostic (1.11e-2)" "unprognostic (2.66e-2)" "unprognostic (2.02e-3)" "unprognostic (3.41e-1)" "unprognostic (1.68e-1)" "unprognostic (1.89e-1)" "unprognostic (1.26e-1)" "unprognostic (3.14e-2)" 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.3 0.0 0.0 2.2 27.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.0 14.4 71.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.1 0.0 0.0 0.0 0.0 33.1 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.1 0.3 0.6 0.0 0.0 0.0 0.0 1.3 0.0 0.0 3.1 1.5 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 1.8 52.2 0.0 0.0 0.3 2.4 0.0 0.8 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 6.3 0.0 0.0 0.0 70.0 13.4 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 6.3 0.0 PLA2R1 "CLEC13C, PLA2-R, PLA2G1R, PLA2IR" ENSG00000153246 "Phospholipase A2 receptor 1" Q13018 2 159932006-160062615 "Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 39.1;thyroid gland: 41.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 33.1;Excitatory neurons: 34.6;Inhibitory neurons: 43.5;Muller glia cells: 33.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 14.5;ASC TERT1: 19.5;BJ hTERT+: 16.2;hTERT-RPE1: 26.3;TIME: 47.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB068217, CAB068218" Approved Approved Cytosol "Secreted to blood" NA NA 960000 "Cluster 1: Thyroid gland - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "CAB068217: AB_2665660, CAB068218: AB_2665661" "unprognostic (2.04e-1)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.39e-2)" "unprognostic (4.91e-3)" "unprognostic (6.01e-2)" "unprognostic (9.71e-2)" "unprognostic (1.09e-1)" "unprognostic (1.40e-2)" "unprognostic (9.38e-3)" "unprognostic (4.30e-3)" "unprognostic (2.82e-1)" "unprognostic (2.14e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (2.62e-1)" "unprognostic (6.58e-2)" "unprognostic (2.02e-1)" 4.7 2.9 0.7 1.4 0.8 0.0 14.9 9.7 2.2 6.9 1.7 3.1 3.9 8.8 2.9 4.7 5.4 9.3 2.5 0.5 1.5 20.8 1.4 2.6 1.9 2.0 2.7 10.8 0.6 19.7 2.2 3.8 2.1 3.1 3.2 5.6 39.1 2.9 0.5 10.9 6.1 6.9 1.4 5.1 1.6 1.0 2.5 0.6 41.9 1.3 2.7 3.9 6.0 1.0 0.2 1.6 0.6 0.0 14.5 19.5 0.1 6.8 16.2 1.3 1.8 0.0 3.4 0.0 0.4 7.2 1.4 3.3 0.1 5.0 1.4 0.0 0.0 0.0 11.8 0.0 1.2 0.0 0.0 7.9 5.4 1.9 2.1 26.3 9.3 0.0 0.0 0.0 2.3 0.1 0.0 0.0 0.2 0.1 2.6 0.0 0.0 0.0 1.4 0.7 0.0 0.0 11.8 2.2 0.0 1.7 2.6 0.2 47.3 0.0 0.8 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.7 0.8 9.7 2.2 0.5 1.5 2.0 2.7 2.1 1.4 2.5 1.0 11.1 6.4 2.8 20.9 0.1 9.4 2.7 18.1 21.6 2.7 22.1 14.5 4.1 5.7 11.3 33.1 0.0 7.3 0.5 1.7 0.0 0.6 0.1 5.6 22.0 4.0 1.2 0.0 34.6 2.0 1.3 14.8 0.0 9.4 1.3 9.6 8.6 0.0 0.6 16.8 43.5 7.2 4.1 0.0 2.1 1.4 16.1 0.5 7.2 25.3 0.0 33.5 0.0 5.5 1.8 5.1 11.3 16.6 0.1 2.6 15.6 2.3 8.1 1.4 6.6 3.4 4.8 0.1 1.0 9.3 5.4 1.5 0.6 6.3 7.5 3.0 PLAAT2 "FLJ20556, HRASLS2, PLAAT-2" ENSG00000133328 "Phospholipase A and acyltransferase 2" Q9NWW9 11 63552770-63563379 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 67.9" "Cell type enhanced" "Detected in single" "dendritic cells: 2.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 8 "memory B-cell: 17.3;naive B-cell: 8.2" "Lineage enriched" "Detected in many" 10 "B-cells: 17.3" "Cell line enriched" "Detected in some" 8 "U-266/70: 128.9" HPA058997 Approved Approved Mitochondria NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "HPA058997: AB_2683874" "unprognostic (4.76e-2)" "prognostic favorable (6.87e-4)" "unprognostic (1.20e-1)" "unprognostic (3.07e-2)" "unprognostic (1.43e-1)" "unprognostic (1.43e-1)" "unprognostic (1.82e-1)" "unprognostic (1.53e-1)" "unprognostic (9.69e-2)" "unprognostic (3.91e-3)" "prognostic unfavorable (5.27e-5)" "unprognostic (1.56e-1)" "unprognostic (2.29e-1)" "unprognostic (1.38e-2)" "unprognostic (2.51e-1)" "unprognostic (2.43e-1)" "unprognostic (1.57e-2)" 0.3 0.0 0.6 0.8 0.6 0.1 9.1 0.5 0.9 0.9 0.3 11.2 67.9 0.3 1.2 1.5 4.7 0.6 0.2 0.5 0.5 8.6 4.6 3.6 0.3 0.7 0.6 0.2 0.0 0.0 0.2 0.2 0.6 0.4 13.7 0.0 0.9 0.5 0.0 0.3 42.5 0.3 0.5 0.7 12.4 0.5 0.6 0.3 0.9 0.0 0.3 1.3 0.2 1.1 0.4 1.7 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.4 0.1 0.3 15.6 0.0 0.9 0.0 0.4 1.0 0.6 0.2 0.1 0.2 0.0 0.1 1.0 0.1 0.2 0.0 0.1 0.1 1.2 0.3 0.0 0.7 0.0 0.0 0.0 6.7 0.0 0.0 0.2 0.3 0.1 8.7 1.9 0.0 0.0 1.5 0.6 0.0 0.0 0.2 0.1 4.0 0.0 0.1 2.2 0.1 0.0 0.0 0.0 0.1 0.0 128.9 16.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.9 17.3 0.2 1.0 0.1 8.2 0.2 0.7 0.1 1.6 0.0 0.9 0.0 3.9 0.6 0.6 0.5 0.9 0.5 0.5 0.7 0.6 0.6 0.5 0.6 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 PLAAT5 "HRASLS5, HRLP5, iNAT, PLAAT-5" ENSG00000168004 "Phospholipase A and acyltransferase 5" Q96KN8 11 63461404-63491194 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "adipose tissue: 16.5;pancreas: 13.6;testis: 53.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;Syncytiotrophoblasts: 1.0" "Cancer enhanced" "Detected in many" "breast cancer: 3.9" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 64 "basophil: 5.4;eosinophil: 16.4" "Lineage enriched" "Detected in single" 97 "granulocytes: 16.4" "Group enriched" "Detected in some" 5 "HAP1: 11.4;NB-4: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042493 Uncertain "Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA042493: AB_10797499" "unprognostic (3.16e-1)" "unprognostic (3.45e-2)" "unprognostic (2.83e-3)" "unprognostic (4.24e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (7.11e-3)" "unprognostic (2.14e-1)" "unprognostic (6.66e-2)" "unprognostic (9.46e-2)" "unprognostic (8.89e-3)" "unprognostic (3.15e-2)" "unprognostic (7.33e-2)" "unprognostic (1.04e-5)" "unprognostic (1.52e-1)" "unprognostic (1.21e-2)" "unprognostic (2.57e-3)" "unprognostic (4.50e-4)" 16.5 0.2 1.2 0.3 0.9 0.1 3.3 0.7 0.8 0.1 0.0 0.7 0.2 0.5 0.2 0.8 0.9 0.6 0.6 1.0 1.3 0.1 0.0 0.6 0.1 1.5 0.5 0.6 13.6 0.0 0.0 0.0 1.0 0.4 0.2 0.5 0.8 1.3 0.1 0.2 0.3 1.4 1.1 0.1 0.5 53.4 0.8 0.0 0.1 0.1 0.0 0.5 0.1 3.2 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.4 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.7 0.8 1.0 1.3 1.5 0.5 1.0 1.1 0.8 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 PLAT ENSG00000104368 "Plasminogen activator, tissue type" P00750 8 42174718-42207709 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 246.0;urinary bladder: 181.4" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 763.3;Urothelial cells: 992.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 604.7;HMC-1: 425.2;hTERT-RPE1: 344.9;LHCN-M2: 298.2;U-2197: 441.2;WM-115: 806.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003412, CAB009335" Supported Approved "Actin filaments" "Secreted to blood" NA NA 9900000 110000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 17: WM-115 - Nervous system development" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" "CAB009335: AB_2237146, HPA003412: AB_1858205" "prognostic favorable (7.57e-4)" "unprognostic (2.23e-1)" "unprognostic (4.08e-1)" "unprognostic (3.39e-1)" "unprognostic (4.88e-3)" "unprognostic (9.39e-2)" "unprognostic (4.65e-3)" "unprognostic (5.78e-2)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (2.98e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (4.95e-4)" "unprognostic (8.72e-3)" "unprognostic (1.37e-2)" "unprognostic (2.63e-2)" "unprognostic (6.09e-2)" 58.9 44.0 14.0 35.6 13.7 0.1 35.1 14.6 17.4 21.8 10.3 55.3 29.9 49.6 16.8 33.7 49.8 40.4 19.3 12.5 16.6 91.9 5.3 41.3 2.3 15.4 15.4 21.5 16.0 246.0 13.3 44.4 16.6 54.0 25.0 2.1 15.6 29.1 8.8 6.2 34.6 32.9 16.0 2.0 41.8 11.9 18.8 4.4 30.9 9.8 2.7 181.4 33.1 14.0 4.2 1.4 29.0 9.1 43.1 61.9 0.9 125.8 216.4 54.2 43.4 1.4 604.7 0.0 4.4 17.1 28.4 14.5 0.3 23.9 78.5 64.6 8.4 0.7 1.0 0.6 253.9 0.2 425.2 65.6 0.4 140.3 6.0 344.9 103.9 0.2 4.6 0.8 298.2 0.0 0.6 0.5 42.3 0.3 48.2 0.2 103.5 0.3 12.6 0.4 0.3 7.4 0.2 0.4 158.7 39.7 1.0 0.3 189.3 11.6 43.1 441.2 15.6 0.2 1.1 0.2 9.7 0.2 806.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 14.0 13.7 14.6 17.4 12.5 16.6 15.4 15.4 16.6 16.0 18.8 14.0 63.5 0.0 13.7 0.0 2.9 10.8 763.3 155.9 7.4 4.7 103.9 66.3 7.4 1.5 19.1 0.0 4.2 0.6 0.9 0.1 0.0 9.3 0.9 4.8 104.2 98.2 0.0 0.0 1.6 0.6 1.3 136.5 2.0 5.1 164.0 89.7 36.4 0.8 1.9 1.7 4.0 0.0 4.1 1.0 17.7 1.5 3.7 4.7 23.2 25.3 1.6 2.1 1.0 42.7 0.3 52.0 0.0 2.6 2.8 193.3 0.2 0.3 4.0 3.8 13.1 10.8 48.3 1.1 0.6 13.6 13.5 0.7 6.0 0.5 0.5 992.1 PLCE1 "KIAA1516, NPHS3, PLCE" ENSG00000138193 "Phospholipase C epsilon 1" Q9P212 10 93993931-94332823 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Guanine-nucleotide releasing factor, Hydrolase, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 70.5;Astrocytes: 69.5;Distal enterocytes: 79.6;Inhibitory neurons: 83.9;Muller glia cells: 82.7;Oligodendrocyte precursor cells: 123.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RT4: 10.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015597, HPA015598" Enhanced Supported Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA015597: AB_1855321, HPA015598: AB_1855322" "unprognostic (4.73e-2)" "unprognostic (1.16e-1)" "unprognostic (4.03e-2)" "unprognostic (3.59e-3)" "unprognostic (3.01e-1)" "unprognostic (2.96e-1)" "unprognostic (1.73e-2)" "unprognostic (4.76e-3)" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.26e-3)" "unprognostic (3.56e-1)" "unprognostic (3.92e-2)" "unprognostic (3.54e-2)" "unprognostic (4.30e-2)" 3.8 2.6 4.5 2.8 4.1 0.2 2.7 3.1 5.6 8.0 7.0 12.6 4.0 9.0 5.3 1.7 4.4 2.5 12.4 3.9 4.7 8.4 0.7 7.3 0.7 3.9 4.8 3.9 14.7 0.8 4.4 2.9 4.0 3.8 7.5 7.3 2.3 5.4 4.1 1.1 5.2 4.2 3.2 6.2 8.3 2.0 5.4 0.5 9.8 6.3 0.6 5.6 5.6 4.2 4.0 6.7 1.8 1.1 0.7 3.2 1.9 2.8 0.6 0.3 0.4 5.3 1.3 0.8 1.3 2.3 1.3 2.6 2.2 0.4 0.6 0.4 2.3 0.5 4.0 0.5 0.0 0.9 0.3 1.8 0.0 1.1 0.0 6.8 0.0 0.4 0.5 0.3 4.2 0.3 0.8 0.9 0.7 7.9 5.0 0.1 3.9 0.2 0.2 10.3 0.9 1.5 3.3 3.6 0.7 4.1 3.5 0.6 0.6 3.0 5.9 2.0 4.4 0.6 0.3 0.4 3.5 1.1 2.2 0.1 0.1 0.0 0.3 0.2 0.2 0.5 0.3 0.2 0.1 0.7 0.5 0.4 0.1 0.2 0.2 0.2 0.1 0.1 4.5 4.1 3.1 5.6 3.9 4.7 3.9 4.8 4.0 3.2 5.4 4.2 8.2 70.5 5.4 69.5 7.0 8.2 9.7 6.8 2.2 12.2 3.6 3.6 34.7 4.3 12.3 0.0 0.0 3.7 2.9 79.6 1.9 1.1 20.7 26.7 18.4 9.7 1.8 0.0 3.1 6.4 2.5 15.3 29.6 10.6 0.0 7.2 4.2 1.6 0.7 6.7 83.9 9.7 4.1 2.4 5.2 5.3 12.2 1.3 7.2 5.6 1.2 82.7 4.1 123.1 2.4 4.2 54.8 23.3 0.9 7.5 11.0 2.5 10.6 18.7 6.6 30.8 37.7 3.7 8.0 1.7 7.4 1.9 4.3 3.7 41.1 10.5 PLG ENSG00000122194 Plasminogen P00747 6 160702238-160754097 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Tissue remodeling" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 2666.4" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 1772.7" "Cancer enriched" "Detected in some" 84 "liver cancer: 180.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000668, CAB016678, HPA021602, HPA048823" Supported "Secreted to blood" NA NA 140000000000 45000000000 "Cluster 85: Liver - Metabolism" "Cluster 15: Hepatocytes - Hemostasis" "CAB000668: , CAB016678: AB_1621208, HPA021602: AB_1855453, HPA048823: AB_2680532" "unprognostic (1.70e-1)" "unprognostic (2.16e-3)" "unprognostic (2.44e-1)" "unprognostic (8.54e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-3)" "unprognostic (6.28e-2)" "unprognostic (7.25e-2)" "prognostic favorable (4.22e-4)" "unprognostic (3.97e-3)" "unprognostic (5.21e-2)" "unprognostic (2.33e-2)" 0.4 0.4 0.3 0.2 0.4 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.3 0.2 0.0 0.1 2.4 0.5 0.1 0.2 0.3 240.9 2666.4 0.4 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.1 0.9 0.0 0.1 0.2 0.1 0.0 0.0 0.5 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.5 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.3 0.2 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.3 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 5.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.6 30.0 0.0 1.8 0.0 0.0 0.3 0.0 19.6 0.0 0.2 3.0 0.1 1.2 0.0 24.0 0.6 0.0 0.0 0.0 0.0 0.1 1.3 0.0 28.5 1772.7 0.1 0.0 0.5 0.0 0.0 35.4 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 235.7 1.5 0.1 0.0 0.4 0.2 0.4 0.4 0.0 0.0 0.0 2.3 0.1 0.0 0.0 PNPLA1 "dJ50J22.1, FLJ38755" ENSG00000180316 "Patatin like phospholipase domain containing 1" Q8N8W4 6 36243203-36313955 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 23.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.9;granulocytes: 4.5;Oligodendrocyte precursor cells: 1.5;Proximal enterocytes: 1.5;Proximal tubular cells: 3.8;Suprabasal keratinocytes: 3.7" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "basophil: 69.8;eosinophil: 18.9" "Lineage enriched" "Detected in many" 17 "granulocytes: 69.8" "Cell line enriched" "Detected in some" 4 "U-937: 17.6" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (3.57e-2)" "unprognostic (2.04e-2)" "unprognostic (1.06e-1)" "unprognostic (3.95e-4)" "unprognostic (1.69e-1)" "unprognostic (1.47e-1)" "unprognostic (7.37e-2)" "unprognostic (2.49e-1)" "unprognostic (8.89e-2)" "unprognostic (1.13e-2)" "unprognostic (2.95e-1)" "unprognostic (2.76e-2)" "unprognostic (2.70e-2)" "unprognostic (9.85e-2)" "unprognostic (2.06e-1)" "unprognostic (2.04e-2)" "unprognostic (1.65e-2)" 0.1 0.2 0.1 0.6 0.2 4.3 0.6 0.3 0.4 0.3 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 4.7 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.2 23.9 0.9 0.2 0.1 0.7 1.7 1.0 0.2 0.1 0.1 0.0 0.1 0.2 0.6 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 3.9 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.0 17.6 0.0 69.8 4.0 18.9 0.0 2.2 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.2 6.2 0.1 1.1 0.0 0.0 1.1 0.1 0.2 0.3 0.4 0.1 0.1 0.2 0.0 0.2 0.1 0.2 0.3 0.0 0.0 0.0 1.0 0.0 0.9 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.2 4.5 0.7 0.0 0.0 0.2 0.0 1.2 0.4 0.0 0.0 0.3 1.3 0.0 0.1 0.0 0.0 0.7 0.0 0.0 1.5 0.7 0.1 0.0 0.0 0.0 0.1 1.5 3.8 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 3.7 0.1 0.0 0.4 0.2 0.2 PNPLA3 "adiponutrin, ADPN, C22orf20, dJ796I17.1, FLJ22012, iPLA2epsilon" ENSG00000100344 "Patatin like phospholipase domain containing 3" Q9NST1 22 43923792-43964488 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 31.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 35.9;Cone photoreceptor cells: 18.8;Hepatocytes: 42.3;Rod photoreceptor cells: 37.3" "Cancer enhanced" "Detected in many" "liver cancer: 4.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 16.7;LHCN-M2: 19.3" "Region enhanced" "Detected in many" "cerebellum: 12.2" "Not detected" "Not detected" HPA058058 Approved Approved Nucleoli,Mitochondria,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoli "Mitochondria, Cytosol" "HPA058058: AB_2683590" "unprognostic (4.74e-3)" "unprognostic (4.52e-2)" "unprognostic (1.76e-1)" "unprognostic (2.31e-1)" "unprognostic (1.36e-2)" "unprognostic (1.89e-1)" "unprognostic (8.93e-2)" "unprognostic (1.02e-1)" "unprognostic (2.63e-1)" "unprognostic (2.93e-1)" "unprognostic (2.33e-2)" "unprognostic (1.05e-1)" "unprognostic (1.39e-3)" "unprognostic (2.52e-3)" "unprognostic (5.91e-2)" "unprognostic (2.02e-2)" "unprognostic (1.01e-1)" 2.6 0.2 0.6 0.5 0.8 0.1 1.6 0.1 1.2 0.6 5.9 0.1 0.8 0.3 0.1 0.2 0.9 0.4 0.2 1.2 0.7 4.5 31.0 0.8 0.3 1.7 1.8 0.3 0.0 0.2 0.0 0.3 2.0 0.0 0.1 6.4 0.7 0.0 1.7 5.8 0.5 0.0 0.2 0.4 0.2 0.4 1.3 0.1 0.1 0.1 0.2 0.0 0.3 0.6 5.1 1.6 16.7 6.8 4.6 5.2 0.5 3.1 1.8 4.1 8.8 5.0 9.0 0.0 2.5 5.2 2.4 4.3 10.6 5.0 3.4 0.0 0.9 0.3 4.5 9.4 7.5 0.0 0.3 6.0 3.8 13.2 0.6 7.0 0.5 0.2 0.0 0.0 19.3 0.7 0.3 0.0 11.5 0.6 0.0 0.1 8.9 0.2 1.7 0.2 1.5 0.1 3.4 1.4 4.8 2.9 5.3 5.8 0.6 1.6 4.9 0.1 0.1 0.1 0.0 0.0 14.3 0.1 6.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.8 0.1 1.2 1.2 0.7 1.7 1.8 2.0 0.2 1.3 0.6 0.4 0.0 0.0 4.2 0.2 0.4 0.5 2.4 0.0 35.9 0.5 0.1 1.3 10.0 1.4 0.0 18.8 0.0 0.2 0.2 0.0 0.4 0.0 1.5 0.5 0.4 1.8 0.0 1.9 0.0 0.1 0.5 0.0 3.6 0.0 1.9 0.7 42.3 0.7 0.0 1.2 0.8 0.0 2.8 0.3 0.3 0.3 0.9 1.8 0.0 0.0 1.1 0.0 0.0 0.8 2.6 0.0 0.7 0.0 0.7 0.4 5.0 0.1 37.3 0.0 1.0 0.8 0.6 0.6 0.0 0.1 0.0 0.2 1.6 0.4 0.4 PODXL "Gp200, PC, PCLP" ENSG00000128567 "Podocalyxin like" O00592 7 131500262-131558217 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 96.2" "Cell type enhanced" "Detected in many" "Adipocytes: 165.8;Cone photoreceptor cells: 87.6;Endothelial cells: 181.1;Glandular and luminal cells: 121.3;Microglial cells: 92.8;Rod photoreceptor cells: 188.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 295.8;NTERA-2: 509.7;SuSa: 640.8;TIME: 474.0;U-251 MG: 226.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002110, CAB016169, HPA045507, CAB062558, CAB068219, CAB068220" Enhanced Supported "Vesicles,Plasma membrane,Centriolar satellite" NA NA 33000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Centriolar satellite" Vesicles "CAB016169: AB_628165, CAB062558: AB_2665627, CAB068219: AB_2665618, CAB068220: AB_2665619, HPA002110: AB_1855512, HPA045507: AB_2679356" "unprognostic (1.26e-1)" "unprognostic (7.68e-2)" "unprognostic (8.28e-3)" "unprognostic (6.46e-3)" "unprognostic (5.16e-3)" "unprognostic (5.85e-2)" "unprognostic (1.63e-2)" "unprognostic (1.05e-1)" "unprognostic (7.95e-3)" "unprognostic (3.52e-1)" "unprognostic (9.20e-3)" "unprognostic (3.40e-1)" "prognostic favorable (2.89e-4)" "unprognostic (2.56e-1)" "unprognostic (8.78e-3)" "unprognostic (3.55e-2)" "unprognostic (1.03e-1)" 20.8 6.8 27.7 8.9 26.5 0.3 21.9 25.2 34.4 26.0 19.0 8.4 5.1 27.5 5.6 8.1 49.0 14.5 29.1 25.2 25.3 96.2 3.0 31.8 5.6 29.2 28.1 6.1 26.0 18.9 1.1 29.3 29.5 8.7 8.6 67.8 16.1 18.9 15.3 4.8 6.2 28.9 22.0 5.6 5.6 2.4 42.0 3.7 28.5 26.1 6.1 9.6 1.0 22.0 50.9 18.9 42.6 16.3 0.5 0.0 2.6 5.4 4.2 16.9 6.1 121.4 83.1 0.3 109.7 295.8 57.1 34.9 34.3 0.7 15.3 5.4 17.3 0.2 115.0 2.7 1.1 4.2 4.0 0.2 0.4 50.5 0.8 9.4 146.3 1.5 10.5 1.8 16.9 18.0 0.5 1.3 509.7 10.0 43.6 16.2 73.1 15.8 1.6 16.6 34.3 8.9 34.7 7.0 0.2 640.8 4.1 2.2 474.0 6.8 26.6 72.5 226.1 2.5 4.5 1.2 27.1 20.1 48.4 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.7 26.5 25.2 34.4 25.2 25.3 29.2 28.1 29.5 22.0 42.0 22.0 165.8 6.4 9.9 3.6 2.4 5.2 0.9 14.0 0.6 9.7 33.3 20.7 22.9 4.3 25.4 27.6 87.6 0.8 1.0 1.0 0.0 4.6 0.8 44.8 13.0 181.1 2.4 2.7 9.4 18.3 0.4 9.2 1.1 121.3 2.5 2.2 65.0 1.0 0.4 5.0 3.3 12.9 4.1 0.9 9.6 1.3 4.7 2.6 5.4 92.8 0.7 10.6 0.0 7.1 3.1 42.7 0.8 0.4 4.3 3.6 0.7 0.8 10.3 188.4 0.0 6.3 8.4 0.3 1.1 1.3 3.1 0.7 3.3 1.9 2.7 5.8 PPFIA4 ENSG00000143847 "PTPRF interacting protein alpha 4" O75335 1 203026498-203078740 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.8;heart muscle: 22.0;skeletal muscle: 18.9" "Group enriched" "Detected in some" 4 "Astrocytes: 12.7;Cardiomyocytes: 35.3;Excitatory neurons: 36.9;Inhibitory neurons: 31.9" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "cerebellum: 58.8;cerebral cortex: 37.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 8.0;hTERT-RPE1: 13.1;RH-30: 13.6;U-266/70: 8.5;U-87 MG: 12.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053419, HPA054132" Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA053419: AB_2682143, HPA054132: AB_2682393" "unprognostic (2.83e-1)" "unprognostic (2.34e-3)" "unprognostic (3.38e-5)" "unprognostic (3.19e-1)" "unprognostic (6.58e-2)" "unprognostic (5.36e-2)" "unprognostic (7.49e-8)" "unprognostic (4.65e-1)" "unprognostic (6.01e-4)" "unprognostic (1.29e-1)" "unprognostic (7.70e-2)" "unprognostic (2.60e-2)" "prognostic unfavorable (1.73e-8)" "unprognostic (6.82e-3)" "unprognostic (9.96e-2)" "unprognostic (1.11e-1)" "unprognostic (4.28e-2)" 0.5 0.6 9.5 0.4 4.2 1.0 0.6 58.8 37.4 3.5 0.0 1.4 0.5 2.3 2.4 1.1 1.0 1.7 22.0 7.6 0.0 5.3 0.3 0.8 0.2 2.2 0.0 0.9 0.1 0.4 1.6 2.8 1.5 1.0 0.2 7.2 1.4 0.6 18.9 2.0 0.8 1.2 0.0 1.6 0.8 3.2 2.5 0.4 0.5 12.0 0.2 0.6 2.0 3.1 8.0 0.0 0.1 1.9 0.0 0.3 0.3 0.4 0.9 0.7 3.2 0.4 0.3 0.4 1.6 1.8 0.2 0.9 0.6 1.5 1.5 0.0 0.6 0.1 0.0 0.0 0.1 0.0 1.0 2.5 0.1 0.4 0.0 13.1 0.0 1.6 0.1 0.3 6.5 1.1 0.6 1.0 0.9 0.0 0.3 1.4 13.6 2.3 0.0 0.0 2.6 3.3 0.8 0.2 1.1 1.2 0.2 0.6 0.0 4.8 2.8 0.1 0.1 8.5 0.2 0.1 12.4 0.7 0.6 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 9.5 4.2 58.8 37.4 7.6 0.0 2.2 0.0 1.5 0.0 2.5 3.1 0.1 0.0 0.0 12.7 0.1 0.0 0.1 3.7 0.6 5.1 0.5 0.3 35.3 0.0 0.9 0.0 6.2 0.1 0.1 0.0 0.0 0.9 2.7 0.4 0.3 0.6 0.0 0.0 36.9 0.0 0.4 1.7 0.0 0.7 0.0 1.8 0.7 0.0 0.3 6.7 31.9 0.1 0.0 0.0 0.0 3.6 0.3 0.7 0.0 4.7 1.9 1.5 1.0 5.5 1.9 0.4 0.1 1.9 0.0 0.1 0.0 0.1 1.0 1.5 0.0 1.1 0.8 0.6 1.4 0.3 0.0 0.3 0.1 0.1 0.0 0.0 PPP1R16B "ANKRD4, KIAA0823, TIMAP" ENSG00000101445 "Protein phosphatase 1 regulatory subunit 16B" Q96T49 20 38805697-38923024 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.6;lymphoid tissue: 41.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 119.4;Inhibitory neurons: 46.8;Oligodendrocyte precursor cells: 49.8;Oligodendrocytes: 238.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 57.3;HMC-1: 59.2;HUVEC TERT2: 35.6;U-266/70: 96.7;U-266/84: 41.8;U-698: 38.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049571, HPA079512" Approved Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "Nuclear speckles" "HPA049571: , HPA079512: " "unprognostic (2.62e-2)" "prognostic favorable (2.11e-4)" "unprognostic (2.67e-3)" "unprognostic (3.35e-3)" "unprognostic (2.19e-1)" "prognostic favorable (7.87e-5)" "unprognostic (1.13e-1)" "unprognostic (4.17e-2)" "unprognostic (4.31e-2)" "unprognostic (6.28e-2)" "unprognostic (4.09e-3)" "unprognostic (4.77e-2)" "unprognostic (3.45e-2)" "unprognostic (8.53e-2)" "unprognostic (3.75e-2)" "unprognostic (1.73e-1)" "unprognostic (7.90e-2)" 13.2 2.9 36.5 19.3 71.6 17.7 8.2 26.1 61.1 3.2 5.1 4.6 3.6 3.4 1.5 3.1 5.8 5.3 5.2 49.3 22.3 27.7 2.4 7.9 37.7 27.8 34.7 1.1 1.5 0.8 2.2 3.7 27.1 1.6 5.1 3.7 2.0 1.9 3.6 1.5 18.0 7.2 24.3 18.1 5.6 0.7 35.7 18.2 3.4 5.7 41.9 6.0 1.6 52.1 0.1 0.7 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 57.3 0.8 0.0 0.9 0.1 1.0 0.1 0.0 1.4 0.2 4.4 0.0 0.0 0.0 0.2 59.2 0.0 0.1 0.0 0.0 0.0 35.6 7.6 1.0 11.9 0.0 0.0 7.4 9.7 7.9 0.1 0.0 5.0 0.0 0.0 0.0 0.0 17.7 19.7 0.0 0.0 0.0 0.7 0.0 3.1 5.5 0.0 0.9 0.0 0.0 96.7 41.8 38.3 0.0 0.0 0.1 0.0 0.2 2.5 3.4 0.5 1.8 5.3 2.3 3.3 0.7 3.3 1.3 1.8 0.0 2.9 0.9 3.3 2.6 1.1 36.5 71.6 26.1 61.1 49.3 22.3 27.8 34.7 27.1 24.3 35.7 52.1 29.3 3.2 3.0 1.3 33.6 1.0 0.0 0.8 0.6 2.3 0.5 0.5 23.5 1.5 4.0 0.0 0.0 0.0 34.0 0.3 0.0 0.0 1.9 0.2 0.2 18.7 0.0 2.7 119.4 0.0 0.0 1.6 4.1 0.3 3.8 0.0 38.6 0.3 0.1 37.0 46.8 0.1 0.0 3.1 3.6 1.5 0.0 3.8 8.8 23.4 20.5 0.3 11.3 49.8 238.0 0.0 0.1 0.0 29.3 0.0 0.0 17.4 3.6 0.3 0.0 0.3 1.0 0.0 0.3 0.3 1.3 0.0 37.4 0.0 0.2 0.3 PRAP1 UPA ENSG00000165828 "Proline rich acidic protein 1" Q96NZ9 10 133347368-133352683 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 1135.4;liver: 675.2" "Cell type enriched" "Detected in some" 9 "Proximal enterocytes: 17736.9" "Cancer enriched" "Detected in many" 5 "liver cancer: 348.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CACO-2: 34.2;Hep G2: 128.3" "HPA038713, HPA052451" Supported "Secreted to digestive system" NA NA 210000000 "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "HPA038713: AB_10673117, HPA052451: AB_2681839" "unprognostic (1.63e-3)" "unprognostic (1.79e-2)" "unprognostic (1.09e-1)" "unprognostic (1.89e-3)" "unprognostic (1.18e-1)" "unprognostic (1.11e-1)" "unprognostic (8.90e-2)" "unprognostic (3.60e-2)" "unprognostic (1.03e-1)" "unprognostic (2.30e-1)" "unprognostic (4.35e-3)" "unprognostic (4.91e-2)" "unprognostic (8.23e-3)" "unprognostic (2.25e-1)" "unprognostic (3.15e-1)" "unprognostic (2.92e-2)" "unprognostic (2.22e-3)" 0.6 0.5 0.7 4.2 0.7 0.5 0.3 0.4 0.7 0.2 6.5 74.6 1053.8 0.8 0.1 0.4 0.7 2.6 0.3 0.6 0.4 145.4 675.2 0.2 1.5 1.2 0.7 0.4 0.1 0.1 0.8 0.1 1.1 0.3 35.7 0.0 1.7 0.3 0.2 1.3 1135.4 1.7 0.4 0.8 2.7 12.2 0.6 0.3 0.2 0.3 0.1 0.3 0.2 0.8 0.2 0.5 0.1 1.2 0.1 0.0 14.6 0.0 0.0 0.0 0.0 34.2 0.6 0.5 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.3 0.5 128.3 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 1.6 0.0 3.5 0.4 5.0 0.0 0.2 0.9 2.9 0.0 0.0 0.9 4.6 0.4 0.0 0.0 0.8 0.0 0.2 0.0 0.0 1.4 1.3 0.0 1.4 0.1 0.4 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.7 0.4 0.7 0.6 0.4 1.2 0.7 1.1 0.4 0.6 0.8 0.0 0.0 0.0 0.0 7.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 8.6 0.0 9.2 0.0 0.2 0.0 773.7 33.2 0.1 1.9 0.6 0.0 0.6 18.4 13.5 0.1 0.2 0.2 0.2 1.5 0.1 8.9 0.0 12.5 1021.3 0.2 0.0 0.0 676.2 0.0 20.9 0.0 7.3 1.2 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1815.7 1.5 0.0 0.1 17736.9 412.0 0.1 0.0 0.0 0.0 0.1 140.2 38.2 0.0 0.0 0.3 3.5 0.0 607.1 0.1 PRDM7 ZNF910 ENSG00000126856 "PR/SET domain 7" Q9NQW5 16 90056566-90092072 "Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "testis: 1.0" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 6.3;Spermatocytes: 14.3;Spermatogonia: 5.1" "Cancer enriched" "Detected in single" 30 "melanoma: 3.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "REH: 3.8;SK-MEL-30: 2.6" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA059944 Approved Uncertain "Nuclear speckles" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 14: REH - Unknown function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear speckles" "HPA059944: AB_2684174" "unprognostic (3.98e-1)" "unprognostic (8.89e-2)" "unprognostic (8.02e-3)" "unprognostic (8.26e-2)" "unprognostic (9.01e-2)" "unprognostic (5.61e-3)" "unprognostic (1.05e-2)" "unprognostic (1.46e-1)" "unprognostic (5.73e-1)" "unprognostic (5.52e-4)" "unprognostic (1.36e-1)" "unprognostic (1.61e-1)" "unprognostic (4.03e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.2 14.3 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PROC ENSG00000115718 "Protein C, inactivator of coagulation factors Va and VIIIa" P04070 2 127418427-127429242 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 40 "liver: 598.5" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 432.9" "Cancer enriched" "Detected in many" 22 "liver cancer: 118.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 9 "plasmacytoid DC: 59.7" "Lineage enriched" "Detected in many" 9 "dendritic cells: 59.7" "Cell line enriched" "Detected in some" 16 "Hep G2: 156.1" "Low region specificity" "Detected in all" "HPA005550, CAB016721, CAB016792" Approved "Secreted to blood" NA NA 5200000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB016721: , CAB016792: , HPA005550: AB_1079687" "unprognostic (2.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (6.64e-2)" "unprognostic (3.13e-2)" "unprognostic (4.90e-3)" "unprognostic (2.63e-1)" "unprognostic (1.67e-1)" "unprognostic (3.29e-1)" "unprognostic (3.74e-3)" "unprognostic (2.56e-2)" "unprognostic (8.12e-3)" "unprognostic (2.01e-2)" "unprognostic (1.71e-1)" "unprognostic (4.60e-3)" "unprognostic (8.06e-2)" 0.2 0.0 0.6 0.1 1.1 1.1 0.1 0.6 1.0 0.4 0.0 1.0 0.8 0.1 0.1 0.1 0.2 0.6 0.1 0.6 1.0 14.8 598.5 0.2 0.6 1.6 0.8 0.2 0.3 0.0 0.3 0.1 1.5 0.2 0.6 0.2 0.2 0.1 0.2 0.6 0.8 0.0 0.4 0.4 2.6 0.1 0.8 0.6 0.2 0.0 0.3 0.4 0.2 1.1 0.1 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 4.1 0.0 0.9 0.1 0.4 9.5 0.0 0.3 0.0 0.0 0.2 0.1 7.8 156.1 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.3 1.6 0.4 2.3 0.7 0.0 0.1 0.0 0.0 0.9 0.4 0.0 1.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.1 0.0 0.0 6.3 0.0 0.0 59.7 0.0 0.3 0.6 1.1 0.6 1.0 0.6 1.0 1.6 0.8 1.5 0.4 0.8 1.1 0.0 0.0 0.0 0.3 4.1 0.8 0.4 11.2 0.0 0.0 0.1 0.0 0.4 47.1 1.2 0.0 0.0 0.0 24.0 3.9 5.9 0.5 0.1 3.4 0.1 0.6 10.3 18.7 0.1 0.2 0.0 0.7 2.0 0.2 0.0 0.0 12.1 432.9 3.7 0.0 0.5 9.3 0.0 9.3 4.0 0.1 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 8.1 0.0 0.0 0.0 3.8 84.8 3.4 0.0 0.0 0.2 0.3 0.1 0.2 0.0 0.1 0.1 1.1 0.0 1.8 0.3 PRODH2 HSPOX1 ENSG00000250799 "Proline dehydrogenase 2" Q9UF12 19 35799988-35813299 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Proline metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 34 "kidney: 140.1;liver: 173.6" "Group enriched" "Detected in some" 13 "Hepatocytes: 157.6;Proximal tubular cells: 559.9" "Cancer enriched" "Detected in some" 5 "liver cancer: 28.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "Hep G2: 33.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA051287 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Cytosol "HPA051287: AB_2681420" "unprognostic (2.58e-1)" "unprognostic (3.41e-3)" "unprognostic (2.75e-2)" "unprognostic (7.03e-2)" "unprognostic (1.73e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 140.1 173.6 0.0 0.4 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.8 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.9 1.5 0.0 12.9 0.0 0.0 0.0 0.0 27.4 0.0 2.8 0.3 0.0 0.3 0.0 2.7 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.1 157.6 0.1 0.0 0.1 0.0 0.0 4.7 0.0 0.9 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 559.9 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 PROZ PZ ENSG00000126231 "Protein Z, vitamin K dependent plasma glycoprotein" P22891 13 113158648-113172386 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 109.2" "Group enriched" "Detected in some" 52 "Hepatocytes: 63.5;Proximal tubular cells: 20.5" "Cancer enriched" "Detected in single" 27 "liver cancer: 12.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 2.2;Hep G2: 3.6" "Not detected" "Not detected" HPA052006 Supported "Secreted to blood" NA NA 1720000000 650000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA052006: AB_2681691" "unprognostic (5.03e-2)" "unprognostic (4.05e-2)" "unprognostic (1.11e-1)" "unprognostic (2.36e-1)" "unprognostic (6.48e-2)" "unprognostic (1.39e-1)" "prognostic favorable (3.46e-4)" "unprognostic (4.10e-1)" "unprognostic (2.21e-1)" "unprognostic (2.50e-1)" "unprognostic (5.20e-2)" "unprognostic (2.87e-1)" "unprognostic (9.83e-2)" "unprognostic (5.63e-2)" "unprognostic (1.41e-1)" "unprognostic (9.99e-2)" "unprognostic (2.51e-4)" 0.1 0.3 0.1 0.3 0.0 0.1 0.0 0.7 0.2 0.2 0.1 0.2 0.2 0.1 0.0 0.1 0.2 0.2 0.1 0.0 0.0 14.4 109.2 0.1 0.3 0.0 0.0 0.1 0.7 0.0 1.2 0.0 0.0 0.4 0.0 0.1 0.3 0.0 0.0 0.5 0.3 0.0 0.0 0.4 0.5 1.7 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.4 0.6 0.3 0.4 0.0 0.0 0.2 0.7 0.0 0.0 0.0 1.4 0.8 0.3 0.0 0.0 0.1 2.2 0.0 0.0 0.0 0.4 1.1 0.4 1.6 3.6 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.5 0.3 0.0 0.5 0.3 0.4 0.8 1.4 0.1 0.6 0.1 0.1 0.0 0.5 1.3 0.0 0.0 0.1 0.6 0.7 0.0 0.4 0.3 0.3 0.0 0.3 0.1 0.7 0.4 0.3 0.7 0.4 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 63.5 0.0 0.0 0.1 0.6 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 20.5 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.1 PRSS55 "CT153, T-SP1, UNQ9391" ENSG00000184647 "Serine protease 55" Q6UWB4 8 10525532-10554166 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 58 "testis: 27.7" "Group enriched" "Detected in some" 46 "Early spermatids: 260.4;Late spermatids: 85.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (3.64e-1)" "unprognostic (8.44e-3)" "unprognostic (6.10e-2)" "unprognostic (7.40e-2)" "unprognostic (6.23e-5)" "unprognostic (6.62e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 260.4 0.0 0.0 0.1 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 85.4 1.5 0.3 0.0 0.0 0.0 0.0 0.0 3.0 0.6 0.1 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PSAT1 PSA ENSG00000135069 "Phosphoserine aminotransferase 1" Q9Y617 9 78297125-78330093 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Serine biosynthesis" "Aminotransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 175.0;liver: 267.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 115.5;Glandular and luminal cells: 145.9;Hepatocytes: 161.7;Proximal tubular cells: 304.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 15.1" "Lineage enriched" "Detected in many" 5 "T-cells: 15.1" "Cell line enhanced" "Detected in many" "hTCEpi: 1170.1;SK-MEL-30: 752.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014882, CAB040567, HPA042924" Enhanced Enhanced Cytosol NA NA 2400000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 22: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "CAB014882: , CAB040567: , HPA042924: AB_2678223" "unprognostic (8.26e-3)" "unprognostic (4.69e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (5.62e-5)" "unprognostic (4.05e-3)" "unprognostic (1.41e-1)" "unprognostic (2.21e-3)" "unprognostic (1.86e-1)" "unprognostic (9.85e-2)" "unprognostic (2.25e-2)" "unprognostic (4.53e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (6.00e-7)" "unprognostic (3.87e-3)" "unprognostic (1.21e-1)" "unprognostic (8.07e-3)" "unprognostic (1.71e-1)" 7.8 65.8 123.3 7.3 124.6 2.0 5.1 130.5 175.0 5.1 92.8 5.9 5.4 4.3 61.6 33.2 34.7 1.7 2.7 122.4 126.5 136.7 267.9 5.1 9.3 130.2 122.4 5.6 129.1 9.7 7.6 3.0 129.9 10.0 5.5 6.2 19.2 4.0 0.6 57.2 4.5 3.3 133.6 6.0 19.4 10.4 120.3 30.0 30.3 0.5 12.4 7.3 11.2 161.6 222.8 146.0 121.1 215.6 35.1 41.2 284.7 184.3 130.4 91.8 170.6 38.2 41.9 143.2 79.8 416.9 82.9 215.3 209.1 203.6 136.4 141.2 73.9 49.2 60.8 293.3 322.0 277.6 84.6 131.1 1170.1 122.0 322.9 22.6 85.0 548.3 53.8 358.2 77.1 83.2 95.8 44.3 278.2 415.1 158.4 46.5 78.6 173.4 126.6 50.9 54.9 127.0 51.1 87.7 752.3 75.9 42.0 344.1 19.9 23.2 73.5 85.9 151.5 242.0 242.7 0.8 268.9 215.6 112.1 0.0 0.0 0.0 5.2 0.0 5.9 3.1 5.0 7.0 0.3 1.3 8.1 7.5 0.3 0.0 0.1 0.0 15.1 3.3 123.3 124.6 130.5 175.0 122.4 126.5 130.2 122.4 129.9 133.6 120.3 161.6 0.4 0.0 0.0 70.2 11.0 41.9 8.8 18.9 115.5 0.9 1.8 3.9 0.6 1.5 4.7 11.0 0.0 32.0 2.2 2.0 62.6 11.5 1.7 77.7 10.3 3.7 3.6 29.9 7.3 48.4 13.7 4.2 6.6 145.9 0.0 0.5 3.6 161.7 5.3 5.0 6.0 4.8 18.3 4.4 2.9 3.8 5.0 3.4 19.6 5.6 3.8 26.7 0.0 48.2 78.8 22.7 0.1 1.9 29.1 16.0 0.3 304.1 3.8 1.1 0.0 33.5 14.3 1.6 3.7 35.5 50.7 9.3 8.6 68.2 4.2 11.8 PTPRO "GLEPP1, NPHS6, PTP-oc, PTP-U2, PTPU2" ENSG00000151490 "Protein tyrosine phosphatase receptor type O" Q16827 12 15322257-15602175 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.8;kidney: 36.3" "Group enriched" "Detected in many" 7 "Excitatory neurons: 193.6;Inhibitory neurons: 231.1;Oligodendrocyte precursor cells: 126.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 8.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "GAMG: 9.9;NTERA-2: 5.8;SH-SY5Y: 6.1;THP-1: 2.7" "Region enhanced" "Detected in all" "olfactory bulb: 175.9" "Low region specificity" "Detected in all" HPA034525 Enhanced "Intracellular and membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA034525: AB_10669785" "unprognostic (3.68e-2)" "unprognostic (3.49e-1)" "unprognostic (9.64e-2)" "unprognostic (1.25e-2)" "unprognostic (7.87e-2)" "unprognostic (2.08e-1)" "unprognostic (5.93e-3)" "unprognostic (5.37e-2)" "unprognostic (2.03e-1)" "unprognostic (3.72e-2)" "unprognostic (2.00e-1)" "unprognostic (5.43e-2)" "unprognostic (4.89e-2)" "unprognostic (2.12e-1)" "unprognostic (1.99e-2)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" 1.8 0.8 8.7 3.0 9.4 0.2 0.8 0.0 10.3 1.3 0.1 10.4 1.7 4.8 1.4 0.4 1.0 1.2 0.5 9.8 8.9 36.3 1.3 6.8 3.1 2.2 3.3 0.4 0.4 0.3 2.4 4.4 5.3 0.5 26.8 7.5 0.5 0.8 0.3 0.4 2.0 6.6 0.9 3.4 0.8 0.5 9.5 1.2 0.3 0.5 3.2 1.5 0.4 2.9 0.0 0.1 0.3 0.1 0.2 0.0 0.2 0.0 0.0 0.5 1.3 0.0 0.0 0.1 0.1 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 5.8 1.2 0.0 0.0 0.0 0.0 0.1 0.2 1.5 6.1 0.9 0.0 0.1 0.1 0.1 2.7 0.0 0.0 0.3 0.0 0.2 0.4 0.0 0.3 0.0 0.1 1.2 0.0 6.0 0.0 0.0 12.3 0.0 8.9 1.7 0.4 8.5 8.6 2.8 1.2 0.1 0.1 12.7 10.9 1.4 3.2 8.7 9.4 0.0 10.3 9.8 8.9 2.2 3.3 5.3 0.9 9.5 2.9 0.2 0.0 0.5 7.5 7.0 0.3 1.3 0.5 0.0 25.2 0.0 0.1 0.7 0.0 1.8 16.5 0.0 0.2 4.0 3.9 0.0 0.4 0.0 0.8 0.2 1.1 3.6 0.0 193.6 0.0 0.2 0.9 0.0 0.6 0.0 0.0 1.1 0.2 26.1 25.2 231.1 8.3 0.0 21.1 10.6 0.6 0.6 10.5 0.0 17.8 13.8 0.6 1.0 126.7 6.3 0.1 9.8 0.4 1.0 0.1 0.1 0.2 0.0 4.8 0.0 2.1 0.7 0.6 1.1 0.1 0.4 0.3 1.0 0.1 22.4 0.8 QDPR "DHPR, PKU2, SDR33C1" ENSG00000151552 "Quinoid dihydropteridine reductase" P09417 4 17460261-17512206 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" Oxidoreductase "Disease variant, Phenylketonuria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 752.2;choroid plexus: 301.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 337.6;Muller glia cells: 387.2;Oligodendrocytes: 481.3;Proximal tubular cells: 527.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058951, HPA065649" Enhanced Approved Mitochondria NA NA 2500000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA058951: AB_2683861, HPA065649: AB_2685526" "unprognostic (1.30e-2)" "unprognostic (4.29e-1)" "unprognostic (8.27e-2)" "unprognostic (2.52e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" "unprognostic (3.29e-3)" "unprognostic (3.80e-3)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "unprognostic (6.82e-3)" "unprognostic (2.07e-1)" "prognostic favorable (7.84e-6)" "unprognostic (1.58e-1)" "unprognostic (2.60e-1)" "unprognostic (9.01e-2)" "unprognostic (3.19e-1)" 66.6 74.3 515.1 10.2 720.1 15.1 26.4 696.9 571.9 15.8 301.8 21.2 25.6 16.5 40.1 15.6 17.3 17.7 43.4 457.6 578.5 110.1 197.2 23.3 11.9 663.0 752.2 18.3 28.8 49.9 32.7 11.8 688.6 28.7 17.0 40.1 36.3 19.5 108.6 16.2 23.9 17.9 524.9 14.3 23.7 12.4 602.6 13.6 22.1 61.2 13.3 14.5 15.1 663.7 33.1 62.5 30.2 35.8 66.1 32.3 41.5 43.2 22.3 47.5 41.6 52.2 46.4 12.2 28.0 30.3 50.8 18.4 40.3 58.4 33.7 35.3 7.3 34.8 33.4 128.3 37.3 46.2 2.9 40.8 35.6 31.6 40.3 25.9 24.5 33.2 37.0 29.0 50.6 19.2 65.0 77.8 44.8 36.7 45.4 27.0 21.0 52.2 48.2 17.5 47.1 64.3 31.9 6.7 156.6 35.0 15.7 19.0 37.7 23.6 41.1 26.5 38.2 43.1 67.7 85.3 52.0 43.1 41.7 0.3 38.9 3.0 31.3 61.3 29.8 18.6 33.1 32.3 48.3 18.3 37.4 32.6 1.1 29.8 48.4 115.1 20.3 34.4 515.1 720.1 696.9 571.9 457.6 578.5 663.0 752.2 688.6 524.9 602.6 663.7 20.3 28.9 31.5 10.7 14.8 20.0 21.3 32.2 18.8 36.2 37.6 28.3 74.4 50.1 19.5 38.6 8.4 69.6 22.8 13.7 109.5 41.1 1.0 11.8 19.1 17.2 174.3 30.1 23.1 23.4 34.2 27.1 27.5 17.8 25.4 42.3 20.7 337.6 80.3 82.4 21.9 31.1 34.6 38.1 23.9 4.8 22.7 32.2 152.9 12.2 23.4 387.2 16.5 15.1 481.3 16.9 11.6 38.0 23.6 23.2 41.4 527.2 6.2 31.4 26.3 27.5 25.4 3.3 58.9 29.7 16.1 18.3 18.5 90.0 35.7 17.3 QPRT QPRTase ENSG00000103485 "Quinolinate phosphoribosyltransferase" Q15274 16 29663279-29698699 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 119.4;liver: 183.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 404.7;Extravillous trophoblasts: 315.1;Hepatocytes: 367.4;Proximal tubular cells: 598.8;Syncytiotrophoblasts: 215.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 4.2;intermediate monocyte: 5.3;myeloid DC: 5.8;non-classical monocyte: 9.0;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 8 "dendritic cells: 5.8;monocytes: 9.0" "Cell line enhanced" "Detected in many" "EFO-21: 597.1;Hep G2: 258.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011887, HPA076010" Enhanced Approved Vesicles "Intracellular and membrane" NA NA 780000 "Cluster 7: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA011887: AB_2668555, HPA076010: " "prognostic unfavorable (5.10e-5)" "unprognostic (2.00e-1)" "unprognostic (9.48e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (9.31e-4)" "unprognostic (1.44e-2)" "unprognostic (8.75e-2)" "unprognostic (1.22e-1)" "unprognostic (8.16e-2)" "unprognostic (1.01e-2)" "unprognostic (2.39e-1)" "unprognostic (6.81e-2)" "unprognostic (3.37e-2)" "unprognostic (1.33e-2)" "unprognostic (2.65e-1)" "unprognostic (1.63e-1)" "unprognostic (1.58e-2)" 8.4 89.4 20.6 4.3 20.2 4.8 6.7 25.8 19.8 50.6 19.4 19.2 61.6 26.1 95.2 4.0 43.6 10.2 26.8 18.5 22.2 119.4 183.5 9.2 6.8 28.6 26.6 31.0 34.5 16.2 5.8 27.3 32.4 7.0 15.2 7.5 13.4 26.1 5.1 5.1 30.3 13.7 23.6 17.2 7.1 4.1 22.8 8.2 6.5 1.2 5.2 10.5 11.5 23.3 0.6 1.4 51.8 56.4 8.8 21.6 167.8 6.0 5.2 8.6 11.0 145.9 91.9 2.3 597.1 10.8 10.0 1.0 18.5 0.6 4.5 0.8 16.7 27.1 2.2 258.0 52.5 4.1 10.4 69.8 1.4 4.8 0.2 12.8 0.2 28.2 75.1 2.9 0.4 154.6 17.6 100.3 162.1 1.9 0.2 89.3 16.3 58.5 47.9 4.2 48.6 103.5 0.0 142.1 118.8 85.1 106.5 112.8 0.6 2.5 24.9 0.9 0.5 1.8 4.9 18.8 4.4 10.4 8.1 0.0 4.2 0.3 0.8 5.3 0.9 0.1 0.6 0.7 5.8 0.0 0.1 0.4 0.8 0.4 9.0 3.1 0.9 1.9 20.6 20.2 25.8 19.8 18.5 22.2 28.6 26.6 32.4 23.6 22.8 23.3 3.1 9.6 24.8 5.2 10.1 3.6 11.7 0.5 1.8 3.3 5.0 2.0 43.2 8.6 3.0 64.4 0.0 404.7 5.8 84.5 50.9 1.2 0.0 93.8 49.5 5.5 28.3 10.5 1.3 55.2 315.1 35.8 0.5 81.0 5.1 6.7 9.7 367.4 147.5 6.7 5.6 47.3 0.0 21.2 18.3 0.5 29.2 19.8 42.7 12.2 4.4 20.8 3.1 11.1 0.5 11.5 78.5 27.1 8.7 4.2 161.0 598.8 1.5 5.0 6.6 3.3 16.2 0.5 3.0 0.2 2.0 215.6 5.7 36.5 104.7 8.3 R3HDML dJ881L22.3 ENSG00000101074 "R3H domain containing like" Q9H3Y0 20 44337043-44351238 "Predicted secreted proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "intestine: 2.4" "Cell type enriched" "Detected in single" 5 "Microglial cells: 1.0" "Cancer enriched" "Detected in single" 5 "colorectal cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.0;OE19: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA070264 Enhanced "Secreted - unknown location" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "HPA070264: AB_2686244" "unprognostic (1.89e-1)" "unprognostic (2.23e-1)" "unprognostic (9.86e-2)" "unprognostic (9.12e-2)" "unprognostic (6.06e-3)" "unprognostic (2.64e-1)" "unprognostic (6.32e-2)" "unprognostic (4.95e-3)" 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.7 2.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.4 0.0 0.0 0.0 0.4 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 RAB11FIP3 "eferin, KIAA0665, Rab11-FIP3" ENSG00000090565 "RAB11 family interacting protein 3" O75154 16 425649-523011 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 151.1" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 384.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028088, HPA028631, HPA030086" Enhanced Enhanced "Nucleoplasm,Vesicles,Cytokinetic bridge,Centriolar satellite,Mitochondria" Yes No "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Centriolar satellite" "Nucleoplasm, Cytokinetic bridge, Mitochondria" "HPA028088: AB_10601672, HPA028631: AB_10601853, HPA030086: AB_10669596" "unprognostic (6.65e-2)" "unprognostic (1.84e-2)" "unprognostic (1.51e-1)" "prognostic favorable (1.22e-4)" "unprognostic (2.87e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (9.87e-5)" "unprognostic (6.71e-2)" "unprognostic (4.74e-1)" "unprognostic (9.66e-2)" "prognostic favorable (3.16e-5)" "unprognostic (1.12e-1)" "prognostic favorable (7.99e-4)" "unprognostic (1.39e-1)" "unprognostic (1.77e-1)" "unprognostic (1.58e-1)" "unprognostic (1.44e-1)" 27.9 32.3 18.0 5.3 18.9 7.0 19.5 21.3 22.6 29.6 7.6 35.1 9.0 31.3 5.5 12.3 27.5 7.4 31.4 21.7 14.0 151.1 37.3 25.2 5.8 14.4 15.8 33.8 47.4 15.9 41.5 6.5 15.2 29.9 3.1 6.1 19.3 7.8 52.2 19.5 27.5 7.1 12.7 26.4 22.2 34.6 16.8 5.3 24.8 15.8 3.2 31.7 19.9 19.0 5.9 14.9 14.6 11.9 20.2 13.2 10.0 10.6 11.6 10.7 7.6 11.5 3.0 15.3 11.0 18.7 8.9 5.5 8.9 13.4 3.9 10.8 14.9 7.9 14.8 31.7 20.9 9.5 8.6 12.7 8.8 11.6 9.9 11.7 17.3 10.7 3.5 6.0 14.4 22.5 10.2 15.9 11.7 5.0 6.8 22.8 10.8 4.6 11.3 4.0 13.8 12.0 11.5 13.6 7.5 5.0 7.6 13.9 29.9 14.8 8.8 13.6 7.0 6.9 6.7 18.8 6.5 5.8 11.7 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 18.0 18.9 21.3 22.6 21.7 14.0 14.4 15.8 15.2 12.7 16.8 19.0 9.4 3.2 1.7 36.9 3.8 3.7 0.7 1.1 2.2 7.7 3.5 4.3 12.4 7.2 4.3 5.5 6.2 1.0 5.7 5.9 27.4 1.6 1.2 6.4 8.7 7.1 3.0 1.7 73.5 1.2 0.2 5.5 2.0 13.1 1.3 8.4 17.9 15.9 0.8 21.9 60.3 3.0 0.0 3.7 1.6 2.6 0.6 4.7 0.0 19.7 0.6 7.2 2.1 46.8 40.7 1.4 3.9 1.9 3.4 0.9 8.1 384.2 3.1 7.6 6.6 5.3 5.4 4.0 2.8 0.3 2.3 0.8 4.4 6.1 5.9 0.3 RAB29 "RAB7L, RAB7L1" ENSG00000117280 "RAB29, member RAS oncogene family" O14966 1 205767986-205775482 "Predicted intracellular proteins" "Differentiation, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 73.1" "Cell type enhanced" "Detected in many" "dendritic cells: 82.3;monocytes: 76.4;NK-cells: 129.8;Proximal tubular cells: 187.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020822, HPA026303" Approved Supported Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "CAB020822: , HPA026303: AB_1856016" "unprognostic (5.38e-2)" "unprognostic (1.76e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.82e-5)" "unprognostic (9.50e-2)" "unprognostic (1.56e-1)" "prognostic unfavorable (1.61e-4)" "unprognostic (2.60e-2)" "unprognostic (3.14e-1)" "unprognostic (5.50e-2)" "unprognostic (2.45e-1)" "unprognostic (3.05e-2)" "unprognostic (1.06e-2)" "unprognostic (2.16e-1)" "unprognostic (1.53e-1)" "unprognostic (8.20e-3)" "unprognostic (1.42e-1)" 13.5 14.4 12.5 20.4 14.1 7.1 14.1 14.3 12.1 8.7 10.5 12.6 10.6 8.3 23.8 7.8 6.2 16.9 13.1 12.3 14.3 73.1 19.4 13.5 35.1 15.9 12.9 7.9 9.2 25.5 5.9 7.2 15.8 13.8 10.1 6.8 19.8 13.9 6.4 5.5 12.4 14.8 14.3 24.3 10.4 4.6 15.3 12.1 33.4 6.0 28.0 15.7 5.7 17.0 20.4 18.6 2.8 13.1 52.5 29.8 9.7 14.1 43.2 28.9 34.4 5.6 28.7 21.6 13.6 24.3 34.6 11.2 32.8 37.3 26.4 88.3 15.3 16.4 7.3 9.5 25.4 16.1 23.2 29.0 24.6 23.3 32.8 24.0 37.2 19.8 16.2 24.2 41.2 7.6 17.7 8.3 13.1 25.4 14.0 3.7 43.1 17.5 33.6 27.7 4.4 12.5 10.0 45.0 37.8 10.3 22.0 13.2 38.7 29.7 15.0 43.5 20.6 39.4 87.0 11.5 30.1 26.3 22.5 92.4 22.6 62.3 92.2 43.8 86.9 50.8 51.0 79.5 33.4 45.8 37.2 63.5 8.8 94.1 53.9 10.4 53.3 51.3 12.5 14.1 14.3 12.1 12.3 14.3 15.9 12.9 15.8 14.3 15.3 17.0 16.3 19.2 17.7 11.1 61.2 0.0 6.3 0.0 13.6 2.1 19.5 16.0 19.3 21.5 6.2 31.3 0.0 12.0 82.3 1.9 29.4 18.7 5.1 2.0 6.3 18.6 4.9 10.8 7.8 10.1 6.4 11.2 10.7 3.5 13.3 9.2 14.6 33.7 32.8 0.0 10.2 3.7 0.0 30.1 0.0 4.1 14.3 34.0 0.0 10.3 76.4 26.5 129.8 10.6 9.8 8.3 4.8 20.7 34.8 10.7 9.5 187.7 2.9 2.0 6.6 10.0 6.7 3.8 11.8 9.3 0.0 2.9 51.7 19.7 5.5 6.9 RASGRF1 "CDC25, CDC25L, GNRP, GRF1, GRF55, H-GRF55, PP13187" ENSG00000058335 "Ras protein specific guanine nucleotide releasing factor 1" Q13972 15 78959906-79090780 "Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 26.5;lung: 7.5;retina: 7.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 80.6;Excitatory neurons: 80.9;Inhibitory neurons: 91.2;Oligodendrocytes: 121.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 8.5;BEWO: 7.7;Karpas-707: 10.4;RPMI-8226: 13.0;U-2 OS: 15.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010413, HPA041965" Approved Supported "Golgi apparatus" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "CAB010413: AB_2238127, HPA041965: AB_10793939" "unprognostic (2.57e-3)" "unprognostic (3.08e-2)" "unprognostic (3.14e-2)" "prognostic favorable (6.14e-6)" "unprognostic (1.90e-1)" "unprognostic (1.15e-3)" "unprognostic (5.37e-2)" "unprognostic (6.16e-2)" "unprognostic (7.58e-2)" "unprognostic (3.25e-2)" "unprognostic (1.00e-1)" "unprognostic (2.03e-1)" "unprognostic (4.02e-6)" "unprognostic (2.35e-1)" "unprognostic (8.02e-2)" "unprognostic (3.81e-2)" "unprognostic (8.81e-2)" 0.1 0.1 4.2 1.0 4.1 0.0 0.1 24.4 24.4 0.6 0.0 0.2 0.2 0.4 0.1 0.1 0.4 0.1 0.0 12.2 6.4 0.7 0.0 7.5 1.3 13.9 10.2 0.8 2.3 0.6 1.1 0.2 16.4 0.5 0.2 7.4 0.1 0.2 0.0 0.0 1.4 0.1 8.7 0.6 0.2 0.3 14.9 0.5 0.0 0.0 1.4 0.3 0.1 26.5 8.5 0.1 0.1 0.0 0.0 0.0 7.7 0.0 0.4 0.5 1.2 0.0 1.5 0.4 0.2 0.0 0.6 0.7 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.4 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 10.4 1.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.9 13.0 0.1 0.3 0.8 0.0 0.0 0.1 1.6 0.7 0.0 1.7 0.0 0.0 15.1 0.0 0.3 0.0 3.8 2.9 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 4.1 24.4 24.4 12.2 6.4 13.9 10.2 16.4 8.7 14.9 26.5 0.2 3.2 80.6 8.5 4.5 0.6 0.6 0.2 0.0 13.7 0.2 0.1 1.0 0.0 1.9 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.2 0.6 0.4 0.5 0.0 0.0 80.9 0.0 2.7 0.3 0.0 1.8 0.0 0.0 0.0 0.0 2.0 25.2 91.2 0.0 0.0 0.3 16.1 0.0 0.0 1.8 3.6 5.6 0.6 1.1 0.0 1.5 121.5 0.3 0.0 0.4 2.1 0.2 0.0 6.8 2.0 2.5 0.0 0.0 0.1 0.0 0.5 0.0 0.3 0.8 0.1 1.6 0.0 0.4 RASSF4 "AD037, MGC44914" ENSG00000107551 "Ras association domain family member 4" Q9H2L5 10 44959407-44995891 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 77.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 157.0;monocytes: 258.7;Muller glia cells: 260.3;Proximal tubular cells: 128.0;Skeletal myocytes: 186.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 84.8;intermediate monocyte: 63.9;myeloid DC: 84.2;non-classical monocyte: 37.9" "Group enriched" "Detected in many" 10 "dendritic cells: 84.2;monocytes: 84.8" "Cell line enhanced" "Detected in many" "Karpas-707: 64.3;RH-30: 162.7;RPMI-8226: 54.9;U-937: 85.4;WM-115: 54.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038834, HPA077069" Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" "Nucleoplasm, Nucleoli" "Cell Junctions, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA038834: AB_10795576, HPA077069: " "unprognostic (1.83e-1)" "unprognostic (8.21e-3)" "unprognostic (1.21e-2)" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (5.14e-2)" "unprognostic (3.15e-2)" "unprognostic (2.18e-2)" "unprognostic (8.81e-2)" "unprognostic (4.83e-2)" "unprognostic (8.75e-3)" "unprognostic (4.20e-1)" "unprognostic (4.11e-3)" "unprognostic (4.02e-2)" "unprognostic (2.22e-2)" "unprognostic (1.42e-1)" "unprognostic (6.20e-2)" 35.3 7.1 57.4 21.7 67.9 8.3 22.7 64.3 58.6 6.5 43.8 18.5 13.6 3.0 8.6 4.7 6.0 10.8 44.8 53.9 58.9 77.3 17.1 11.9 19.7 63.4 64.0 3.6 39.5 5.0 13.0 12.7 65.9 7.9 6.0 26.9 16.7 10.9 14.8 4.8 13.8 8.7 55.8 20.1 9.4 9.0 65.3 10.4 40.7 17.6 9.1 11.4 7.0 69.7 1.4 0.3 6.0 11.4 17.9 1.0 4.1 0.7 1.1 2.0 3.5 5.0 0.6 0.1 2.3 0.8 3.9 0.0 2.6 2.8 2.8 37.8 0.0 0.1 0.2 39.7 19.0 2.6 0.0 13.1 0.0 1.9 0.2 10.9 3.0 1.6 0.0 64.3 2.9 0.0 3.0 43.1 1.2 0.2 1.2 8.1 162.7 54.9 0.4 1.2 1.0 0.8 0.0 0.5 2.0 10.7 1.1 32.4 0.0 0.4 3.6 3.0 6.5 0.7 0.7 0.1 18.9 85.4 54.8 0.0 84.8 0.1 8.7 63.9 0.2 0.0 0.6 3.7 84.2 0.0 0.6 2.6 3.0 6.9 37.9 2.2 0.3 48.9 57.4 67.9 64.3 58.6 53.9 58.9 63.4 64.0 65.9 55.8 65.3 69.7 8.9 19.2 17.2 77.4 3.7 3.7 1.4 3.2 1.2 22.5 9.7 7.0 47.9 37.1 13.1 16.5 4.2 1.2 20.3 10.1 17.6 45.3 1.4 6.4 13.7 9.2 11.5 0.0 17.0 3.8 1.2 28.6 1.5 14.8 1.3 4.2 6.1 20.1 157.0 37.0 33.6 7.4 12.2 84.7 94.3 4.4 10.5 91.0 8.8 35.6 258.7 260.3 54.6 37.7 38.2 4.0 11.3 2.2 4.1 1.0 45.0 128.0 5.9 13.3 26.3 186.4 25.9 0.6 1.9 0.8 1.7 2.6 8.0 4.9 15.0 0.7 RBP5 CRBPIII ENSG00000139194 "Retinol binding protein 5" P82980 12 7115736-7128889 "Plasma proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 443.5;liver: 324.2" "Cell type enriched" "Detected in many" 8 "Proximal tubular cells: 3197.2" "Group enriched" "Detected in all" 8 "liver cancer: 70.1;renal cancer: 126.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 6.0;Hep G2: 13.4;K-562: 26.3" HPA038723 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" Vesicles "HPA038723: AB_2676175" "unprognostic (5.70e-3)" "unprognostic (7.34e-2)" "unprognostic (2.72e-2)" "unprognostic (1.53e-2)" "unprognostic (1.87e-2)" "unprognostic (1.39e-3)" "unprognostic (2.49e-2)" "prognostic favorable (8.37e-4)" "unprognostic (1.04e-1)" "unprognostic (2.65e-1)" "unprognostic (1.13e-2)" "unprognostic (1.13e-1)" "unprognostic (1.04e-1)" "unprognostic (1.83e-2)" "unprognostic (3.33e-2)" "unprognostic (4.22e-1)" "prognostic favorable (3.68e-4)" 6.4 11.7 0.0 15.0 0.1 1.6 5.1 0.3 0.3 11.2 0.2 8.5 4.6 8.6 3.2 3.8 8.1 5.9 1.4 0.0 0.0 443.5 324.2 3.8 31.2 0.5 0.3 4.9 5.2 1.3 6.2 0.3 0.3 10.0 4.9 0.8 3.7 5.0 0.7 2.4 20.6 5.4 0.0 97.1 5.2 2.2 0.2 14.2 7.9 0.0 21.4 7.4 4.6 0.0 0.9 1.3 0.0 0.3 0.0 0.0 0.2 1.1 0.0 0.0 0.2 1.1 1.2 1.0 0.3 0.0 0.1 1.2 0.1 0.0 0.0 1.6 0.0 6.0 3.9 13.4 0.0 0.2 0.9 0.2 0.0 0.0 0.0 2.4 0.0 0.6 26.3 0.7 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.2 0.0 0.1 0.1 1.2 0.0 0.2 1.4 0.9 0.0 0.6 0.5 0.7 0.7 0.6 0.5 2.8 0.4 0.3 0.1 0.0 0.3 1.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.5 0.3 0.3 0.0 0.2 0.0 4.9 0.0 0.6 0.7 15.2 1.5 0.5 0.1 0.0 1.2 1.3 1.3 0.1 5.7 0.1 80.9 0.0 0.1 0.3 0.1 352.1 0.2 4.1 0.3 1.7 28.8 0.0 0.0 2.1 0.4 0.0 8.2 0.0 0.5 0.0 0.2 8.9 361.1 0.1 5.0 1.1 0.0 0.0 8.1 2.6 6.7 2.5 16.6 0.0 1.9 0.0 1.4 0.0 0.5 0.1 0.2 0.0 0.4 0.1 0.5 0.0 3197.2 0.9 1.7 0.0 0.1 4.3 0.7 0.4 0.2 2.3 0.0 7.3 2.4 0.1 0.3 RDH12 "FLJ30273, LCA13, RP53, SDR7C2" ENSG00000139988 "Retinol dehydrogenase 12" Q96NR8 14 67701886-67734451 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Oxidoreductase "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "retina: 222.7;skin 1: 63.8" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 146.0;Rod photoreceptor cells: 453.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (4.25e-3)" "unprognostic (4.50e-3)" "unprognostic (1.16e-1)" "unprognostic (7.53e-2)" "unprognostic (2.99e-1)" "unprognostic (1.99e-1)" "unprognostic (6.70e-2)" "unprognostic (2.13e-1)" "unprognostic (1.69e-2)" "unprognostic (2.72e-3)" "unprognostic (7.59e-2)" "unprognostic (2.02e-1)" "unprognostic (1.42e-2)" "unprognostic (6.47e-2)" "unprognostic (7.83e-2)" "unprognostic (3.58e-1)" "unprognostic (3.92e-1)" 0.1 4.1 1.3 0.1 1.0 0.1 2.2 1.0 1.4 11.0 0.4 0.0 0.3 0.0 8.7 22.1 0.5 17.6 0.0 0.9 1.2 13.6 3.8 0.1 0.0 1.2 2.3 0.0 3.2 0.0 0.9 0.1 1.2 0.5 0.0 222.7 1.7 0.1 0.1 63.8 0.1 0.0 0.6 0.0 12.4 0.1 4.6 0.4 1.2 0.0 1.6 0.0 23.6 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.0 1.0 1.4 0.9 1.2 1.2 2.3 1.2 0.6 4.6 1.1 0.0 0.0 0.0 0.7 0.0 4.7 0.3 0.0 0.6 39.8 0.1 0.1 0.0 20.0 0.3 1.8 146.0 0.0 0.0 0.1 0.0 0.7 0.2 1.8 1.1 2.2 0.0 0.0 1.2 1.7 0.0 0.4 14.3 1.7 0.0 0.0 0.0 5.7 0.2 20.2 0.9 0.0 0.0 0.6 0.9 0.0 0.3 0.2 1.8 1.0 0.0 53.0 0.0 1.5 0.2 1.5 2.6 0.0 0.0 0.3 0.1 12.5 0.2 453.2 0.0 0.0 0.2 0.0 0.1 4.7 38.6 0.0 0.1 0.1 0.1 0.3 REEP6 "C19orf32, DP1L1, FLJ25383, Yip2f" ENSG00000115255 "Receptor accessory protein 6" Q96HR9 19 1491166-1497927 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 217.5;liver: 398.0;testis: 283.9" "Cell type enhanced" "Detected in many" "Early spermatids: 559.1;Late spermatids: 3135.0;Proximal enterocytes: 898.7" "Cancer enhanced" "Detected in all" "liver cancer: 114.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 57.9;Hep G2: 56.2;K-562: 155.7;T-47d: 121.4" "HPA003895, HPA048015" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 45: Intestine - Brush border" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA003895: AB_1845723, HPA048015: AB_2680233" "unprognostic (1.21e-1)" "unprognostic (1.56e-1)" "unprognostic (7.76e-2)" "unprognostic (1.63e-3)" "unprognostic (3.24e-1)" "unprognostic (2.43e-2)" "unprognostic (1.92e-1)" "unprognostic (6.85e-2)" "unprognostic (7.38e-2)" "unprognostic (4.56e-1)" "unprognostic (1.49e-1)" "unprognostic (1.93e-1)" "unprognostic (1.40e-2)" "unprognostic (2.17e-1)" "unprognostic (8.08e-2)" "unprognostic (2.83e-1)" "unprognostic (5.38e-2)" 8.4 86.5 11.1 1.3 12.4 1.2 17.5 10.1 18.0 5.6 7.7 3.0 217.5 3.5 14.6 14.3 4.6 7.0 3.9 12.7 8.8 22.1 398.0 1.6 1.3 9.7 10.1 7.7 28.5 2.0 9.8 1.6 9.9 20.1 1.7 94.0 17.9 6.8 2.0 9.3 199.6 0.9 8.4 1.7 4.2 283.9 12.1 0.7 6.0 0.7 1.0 9.2 7.0 10.9 7.3 9.2 2.6 34.3 5.6 2.0 39.5 1.8 0.7 1.9 1.9 57.9 22.5 3.9 12.2 1.1 2.3 7.3 9.8 0.6 1.0 1.9 4.1 21.3 1.3 56.2 4.2 1.6 6.6 4.7 4.1 0.4 1.4 3.2 1.1 4.9 155.7 5.0 0.3 29.6 1.8 4.7 12.8 21.1 19.5 4.9 1.1 10.0 10.9 2.7 0.7 17.2 9.8 14.2 6.3 1.9 121.4 5.7 3.4 2.8 5.4 8.7 1.2 16.4 5.3 0.8 11.2 9.4 8.2 0.0 1.1 0.0 5.5 1.2 2.8 0.1 1.4 1.2 1.9 0.6 2.0 2.2 0.0 4.9 4.3 3.3 1.6 1.6 11.1 12.4 10.1 18.0 12.7 8.8 9.7 10.1 9.9 8.4 12.1 10.9 1.5 3.2 3.2 2.6 2.7 6.8 7.9 6.8 10.8 30.4 47.4 20.3 1.8 91.5 10.5 5.5 33.3 69.4 2.5 7.8 7.9 34.5 559.1 4.5 7.1 4.2 6.0 10.1 1.5 69.2 12.8 4.7 2.6 3.0 10.2 132.9 5.0 267.4 9.6 23.5 1.2 51.9 4.1 6.3 4.3 3135.0 34.2 4.1 30.2 0.0 1.7 44.2 2.1 0.0 1.5 25.0 53.6 16.6 1.9 13.1 898.7 52.0 8.3 292.8 19.7 0.8 3.3 29.9 36.5 17.5 6.7 36.0 4.3 50.1 70.7 14.7 RGN "RC, SMP30" ENSG00000130988 Regucalcin Q15493 X 47078355-47093314 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 184.7;liver: 383.7" "Cell type enhanced" "Detected in many" "Distal tubular cells: 58.7;Granulosa cells: 67.8;Hepatocytes: 175.7;Muller glia cells: 54.5;Peritubular cells: 69.6;Proximal tubular cells: 174.4" "Cancer enriched" "Detected in many" 6 "liver cancer: 47.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 21.7;fHDF/TERT166: 6.9;Hep G2: 32.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA029102, HPA029103, HPA029104" Enhanced Approved Cytosol NA NA 280000 "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA029102: AB_10599846, HPA029103: AB_10602097, HPA029104: " "unprognostic (1.80e-1)" "unprognostic (1.25e-1)" "unprognostic (1.39e-1)" "unprognostic (5.56e-3)" "unprognostic (8.22e-3)" "unprognostic (1.32e-2)" "prognostic favorable (7.55e-4)" "unprognostic (2.60e-3)" "unprognostic (2.23e-2)" "unprognostic (8.38e-2)" "unprognostic (3.37e-2)" "unprognostic (1.14e-2)" "prognostic favorable (5.10e-10)" "unprognostic (1.69e-2)" "unprognostic (2.43e-1)" "unprognostic (7.82e-2)" "unprognostic (5.22e-2)" 7.8 184.7 19.2 0.7 20.8 0.0 3.4 23.0 19.9 12.2 25.9 8.4 13.2 7.2 4.5 3.2 5.4 5.0 13.9 19.0 20.2 56.7 383.7 18.9 1.0 21.6 19.8 21.4 34.0 5.8 8.8 12.1 20.7 13.4 2.1 8.0 14.4 17.3 11.8 1.5 13.6 4.4 21.3 3.7 11.9 3.5 19.3 0.5 18.9 11.3 0.5 7.6 6.0 21.2 0.0 0.0 0.2 0.0 0.0 0.2 0.5 0.4 0.8 0.0 0.0 21.7 0.0 0.0 1.1 6.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 32.8 1.0 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.8 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 20.8 23.0 19.9 19.0 20.2 21.6 19.8 20.7 21.3 19.3 21.2 0.6 6.4 3.6 16.3 0.6 0.5 4.9 0.2 1.8 9.6 2.4 7.0 27.5 8.6 0.7 14.7 0.0 0.1 0.0 0.2 58.7 13.9 0.4 3.4 7.4 2.4 4.8 2.7 10.8 8.9 0.3 11.2 3.1 0.5 0.0 67.8 11.4 175.7 0.1 5.0 4.9 0.2 0.0 5.3 1.2 2.1 24.8 1.2 1.8 4.7 0.0 54.5 0.0 27.2 13.7 5.0 1.2 69.6 0.7 1.1 0.2 174.4 1.7 3.1 13.1 22.3 11.3 0.2 0.2 0.5 0.3 0.3 0.7 14.5 0.7 1.3 RHBG SLC42A2 ENSG00000132677 "Rh family B glycoprotein" Q9H310 1 156369211-156385219 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ammonia transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 9.8" "Group enriched" "Detected in some" 4 "Granulosa cells: 89.9;Theca cells: 91.3" "Group enriched" "Detected in some" 5 "liver cancer: 14.2;renal cancer: 5.1;urothelial cancer: 4.1" "Region enriched" "Detected in single" 17 "cerebellum: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CACO-2: 2.9;Hep G2: 3.0;RT4: 5.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA042726, HPA048489" Enhanced Approved Nucleoplasm NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 15: RT4 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA042726: AB_2678131, HPA048489: AB_2680417" "unprognostic (1.20e-1)" "unprognostic (2.05e-1)" "unprognostic (4.55e-3)" "unprognostic (5.04e-2)" "unprognostic (2.95e-2)" "unprognostic (3.76e-3)" "unprognostic (2.00e-1)" "unprognostic (1.19e-1)" "unprognostic (1.49e-1)" "unprognostic (2.45e-1)" "unprognostic (3.72e-1)" "unprognostic (3.63e-2)" "unprognostic (4.91e-2)" "unprognostic (1.51e-1)" "unprognostic (1.96e-1)" "unprognostic (1.91e-3)" "prognostic favorable (8.06e-4)" 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 9.8 1.9 0.0 0.0 0.1 0.0 2.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 22.0 0.0 0.0 0.0 0.0 19.6 0.3 10.3 0.3 0.0 0.1 0.0 0.0 0.2 0.6 0.1 1.3 0.0 0.1 0.0 89.9 0.0 10.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 12.4 0.3 0.1 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.1 1.3 0.2 0.0 0.0 0.0 0.8 2.3 0.4 0.0 0.4 0.0 0.0 91.3 0.0 0.1 RHOBTB1 KIAA0740 ENSG00000072422 "Rho related BTB domain containing 1" O94844 10 60869438-61001440 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 144.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 135.5;Horizontal cells: 334.8;Oligodendrocytes: 155.5;Syncytiotrophoblasts: 302.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 67.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA040205, HPA040226" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm Cytosol "HPA040205: AB_2676883, HPA040226: AB_10795377" "unprognostic (1.25e-1)" "unprognostic (2.72e-2)" "unprognostic (6.69e-3)" "unprognostic (2.63e-2)" "unprognostic (1.08e-1)" "unprognostic (1.34e-1)" "unprognostic (3.22e-3)" "unprognostic (1.64e-1)" "unprognostic (2.25e-1)" "unprognostic (4.31e-1)" "unprognostic (1.39e-1)" "unprognostic (5.53e-2)" "unprognostic (8.54e-3)" "unprognostic (1.38e-1)" "unprognostic (1.79e-1)" "unprognostic (7.16e-2)" "unprognostic (2.57e-2)" 7.8 13.9 5.6 4.1 6.6 0.9 7.1 5.2 7.8 15.7 5.3 8.1 6.6 14.5 2.4 3.0 10.9 11.5 13.5 4.6 4.7 30.8 6.8 10.6 2.8 6.1 6.1 10.2 9.2 8.6 3.2 37.1 6.3 7.7 4.8 24.3 2.1 9.9 144.2 3.6 5.6 12.1 4.9 14.9 20.8 15.1 7.6 1.9 3.3 19.6 1.2 7.4 7.5 7.8 0.2 12.0 17.8 0.0 8.3 7.3 0.0 5.3 4.8 4.3 6.4 0.6 0.2 0.0 21.9 28.0 2.0 0.3 5.3 1.6 5.0 0.0 4.8 1.1 8.8 67.3 9.0 1.4 0.4 10.6 3.0 2.6 2.7 16.5 20.6 3.8 10.2 0.0 19.1 0.4 5.2 0.0 7.7 0.2 7.9 4.5 24.9 6.4 14.1 0.7 4.9 19.0 6.3 6.9 6.9 11.1 1.4 2.4 18.5 8.2 21.1 0.2 5.9 0.0 0.0 0.0 4.1 3.9 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 5.6 6.6 5.2 7.8 4.6 4.7 6.1 6.1 6.3 4.9 7.6 7.8 13.7 16.0 8.7 3.6 1.0 1.8 1.0 0.5 0.6 3.4 3.7 2.5 29.5 1.5 2.3 1.8 135.5 66.1 0.2 0.7 1.9 3.8 75.2 11.0 14.7 13.6 8.3 3.8 74.3 16.0 3.4 8.6 34.1 4.5 0.0 59.0 17.9 9.6 11.3 334.8 23.1 7.7 4.1 21.5 1.4 35.3 8.1 14.1 1.8 57.1 0.4 16.0 0.0 14.1 155.5 16.4 2.5 4.9 0.1 1.2 1.5 36.4 10.2 25.1 6.6 16.7 11.8 2.8 1.4 0.6 1.4 302.4 0.8 15.2 4.3 0.4 RIDA "HRSP12, P14.5, PSP, UK114" ENSG00000132541 "Reactive intermediate imine deaminase A homolog" P52758 8 98102344-98117171 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "kidney: 496.2;liver: 1536.9" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 1579.1" "Group enriched" "Detected in all" 5 "liver cancer: 162.2;renal cancer: 42.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 191.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022856, HPA023489" Enhanced NA NA 5000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA022856: AB_1858253, HPA023489: AB_1858252" "unprognostic (1.67e-2)" "unprognostic (3.73e-1)" "unprognostic (1.29e-1)" "unprognostic (1.10e-1)" "unprognostic (4.16e-1)" "unprognostic (2.20e-2)" "prognostic favorable (9.61e-6)" "unprognostic (6.08e-2)" "unprognostic (1.13e-1)" "unprognostic (3.15e-1)" "unprognostic (2.81e-1)" "unprognostic (4.46e-1)" "unprognostic (1.55e-1)" "unprognostic (1.73e-1)" "unprognostic (2.04e-1)" "unprognostic (2.08e-2)" "unprognostic (1.51e-2)" 50.1 48.4 93.1 11.4 96.4 7.5 19.1 95.5 131.7 11.2 83.8 24.5 30.5 8.4 22.7 14.3 9.4 22.7 32.3 89.2 95.0 496.2 1536.9 9.5 10.1 91.6 97.8 23.4 27.0 24.6 10.0 10.8 95.5 19.3 24.6 26.6 16.4 11.6 40.0 10.6 21.8 10.8 92.6 7.4 24.8 17.2 100.0 11.2 15.9 41.0 12.3 15.5 7.9 91.0 44.0 37.5 29.3 36.6 65.5 50.4 33.0 39.7 28.0 26.4 31.0 51.4 28.4 62.5 49.6 29.4 34.5 30.8 65.4 56.9 52.5 22.3 28.6 45.0 25.6 55.6 29.9 17.6 7.0 44.4 19.5 36.6 39.9 32.4 34.2 65.3 82.7 12.9 35.5 57.8 35.6 50.1 47.0 191.4 67.8 41.0 21.7 18.4 64.6 31.6 32.2 15.7 25.5 17.4 29.2 37.4 44.5 23.5 20.9 20.6 12.5 33.7 16.3 31.2 46.1 30.9 35.0 39.0 13.2 0.2 9.0 5.6 6.6 7.8 8.7 13.8 9.4 10.1 11.1 11.5 12.0 13.0 1.9 10.3 8.3 8.5 13.9 8.1 93.1 96.4 95.5 131.7 89.2 95.0 91.6 97.8 95.5 92.6 100.0 91.0 7.8 25.6 22.4 0.0 7.4 0.0 0.0 0.0 0.0 0.0 13.8 15.1 0.0 0.0 1.8 47.8 0.0 31.1 3.2 0.0 285.7 19.7 0.0 25.1 12.3 5.0 0.0 0.0 0.0 8.5 29.9 7.9 0.0 9.4 2.5 17.7 0.0 0.0 24.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 5.7 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.8 0.0 0.0 1579.1 5.8 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 14.4 6.3 22.3 0.0 0.0 RNASE2 "EDN, RAF3, RNS2" ENSG00000169385 "Ribonuclease A family member 2" P10153 14 20955487-20956436 "Enzymes, Plasma proteins, Predicted secreted proteins" Chemotaxis "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 49 "bone marrow: 1713.7" "Cell type enhanced" "Detected in some" "Erythroid cells: 30.7;Kupffer cells: 174.3;Macrophages: 82.2;monocytes: 54.6" "Cancer enriched" "Detected in many" 7 "glioma: 14.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 457.5;eosinophil: 1352.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 1352.6" "Group enriched" "Detected in some" 303 "HL-60: 539.0;NB-4: 539.8;THP-1: 1405.4;U-937: 1295.9" HPA044983 Enhanced "Secreted to blood" NA NA 200000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA044983: AB_10963689" "unprognostic (6.66e-2)" "unprognostic (3.00e-1)" "unprognostic (6.85e-2)" "unprognostic (7.68e-2)" "unprognostic (2.73e-2)" "unprognostic (9.26e-2)" "unprognostic (4.94e-3)" "unprognostic (6.77e-2)" "unprognostic (9.54e-2)" "unprognostic (3.24e-2)" "unprognostic (3.25e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (3.28e-13)" "unprognostic (2.27e-2)" "unprognostic (7.14e-3)" "unprognostic (5.33e-2)" "unprognostic (1.50e-1)" 7.1 6.0 3.0 9.1 2.8 1713.7 1.7 2.9 5.5 2.3 4.4 2.2 0.2 2.1 0.3 0.9 5.7 2.6 4.0 2.8 4.2 1.7 4.6 12.2 1.9 5.4 4.1 1.5 1.7 0.5 1.7 1.8 4.4 1.7 0.7 1.7 1.9 0.2 0.7 2.9 1.4 9.7 4.5 35.1 2.1 0.7 4.2 14.8 0.9 0.6 0.6 5.2 1.4 6.3 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.1 0.0 539.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 539.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.0 1405.4 0.0 0.0 0.1 0.0 1.2 0.0 0.2 0.7 0.0 1295.9 0.0 457.5 109.0 1352.6 0.4 19.3 0.8 0.3 0.4 0.0 191.8 0.4 0.4 0.4 9.8 0.1 2.8 2.6 0.1 39.9 3.0 2.8 2.9 5.5 2.8 4.2 5.4 4.1 4.4 4.5 4.2 6.3 0.2 3.2 0.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 1.4 0.0 1.9 0.0 0.5 0.0 0.0 1.3 0.0 30.7 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.4 2.2 13.0 0.0 0.0 0.0 0.0 174.3 0.7 1.7 0.3 82.2 0.0 0.0 54.6 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 19.7 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 RNF157 KIAA1917 ENSG00000141576 "Ring finger protein 157" Q96PX1 17 76142465-76240493 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 86.9;retina: 59.0;skeletal muscle: 73.9;testis: 31.4;tongue: 43.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 114.1;Cone photoreceptor cells: 189.7;Excitatory neurons: 64.6;Horizontal cells: 180.0;Inhibitory neurons: 92.7;Rod photoreceptor cells: 70.9" "Cancer enhanced" "Detected in many" "glioma: 11.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 2.2;T-cells: 5.8" "Cell line enhanced" "Detected in many" "HDLM-2: 100.9;U-266/70: 50.6;U-266/84: 45.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021854, HPA021991, HPA023922" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "Golgi apparatus" Vesicles "HPA021854: AB_10600307, HPA021991: AB_10601112, HPA023922: AB_10602202" "unprognostic (4.21e-1)" "unprognostic (4.62e-2)" "unprognostic (1.55e-2)" "unprognostic (2.63e-3)" "unprognostic (4.93e-2)" "unprognostic (5.06e-2)" "unprognostic (2.07e-3)" "unprognostic (4.21e-1)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "unprognostic (1.04e-3)" "unprognostic (4.02e-1)" "unprognostic (8.26e-2)" "unprognostic (8.69e-3)" "unprognostic (2.28e-1)" "unprognostic (2.75e-2)" "unprognostic (1.38e-1)" 13.6 3.3 36.4 3.7 39.1 2.2 4.9 34.1 86.9 1.4 9.8 9.8 9.6 1.4 3.4 1.0 1.8 1.3 6.4 56.9 34.5 5.8 2.5 1.4 5.2 59.7 41.9 1.2 3.4 14.6 6.3 1.6 61.1 1.9 7.0 59.0 1.9 1.5 73.9 1.0 10.3 1.8 34.1 3.5 3.9 31.4 51.5 2.8 3.4 43.7 2.7 3.0 1.0 58.1 0.2 7.1 29.3 10.7 8.8 4.4 13.4 0.3 8.9 1.9 1.3 3.3 3.1 0.0 4.2 0.5 6.9 0.2 26.0 0.1 1.6 100.9 8.9 0.0 2.9 4.7 1.7 1.4 10.9 2.4 0.1 3.7 0.1 1.5 0.2 4.7 16.0 0.3 3.6 8.0 4.4 0.8 4.8 5.5 21.1 0.0 0.3 0.1 3.4 3.2 5.1 24.0 5.3 0.1 11.5 6.5 0.7 5.1 0.2 1.9 2.3 14.4 9.6 50.6 45.5 0.1 0.8 0.1 15.1 2.2 0.2 0.3 1.6 0.1 3.4 0.2 3.4 2.7 0.1 0.4 5.8 3.9 1.2 0.7 0.2 0.3 1.3 1.0 36.4 39.1 34.1 86.9 56.9 34.5 59.7 41.9 61.1 34.1 51.5 58.1 2.8 3.2 3.3 33.3 1.5 2.0 0.8 0.2 0.6 114.1 0.8 0.9 9.0 11.5 1.3 1.8 189.7 0.6 5.0 5.3 0.0 1.9 27.8 0.6 3.7 4.4 2.4 5.5 64.6 1.1 0.4 3.1 0.0 1.5 0.0 0.9 0.7 4.3 0.4 180.0 92.7 7.4 0.0 0.8 6.0 29.1 11.5 1.1 1.8 3.7 1.4 35.9 8.2 62.8 35.0 0.1 3.4 13.9 2.1 0.9 19.3 9.1 0.7 70.9 0.0 2.9 1.3 22.7 25.0 0.0 2.3 0.3 15.5 1.3 18.2 1.5 RNF186 FLJ20225 ENSG00000178828 "Ring finger protein 186" Q9NXI6 1 19814029-19815283 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 67.2;intestine: 131.1;pancreas: 43.4" "Group enriched" "Detected in some" 5 "Distal enterocytes: 41.6;Enteroendocrine cells: 86.6;Intestinal goblet cells: 46.6;Paneth cells: 123.4;Proximal tubular cells: 142.7;Undifferentiated cells: 110.3" "Group enriched" "Detected in many" 4 "colorectal cancer: 18.5;renal cancer: 12.1;stomach cancer: 7.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "RPMI-8226: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA034547, HPA035558" Enhanced NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA034547: AB_10670975, HPA035558: AB_2674678" "unprognostic (1.66e-2)" "unprognostic (2.49e-2)" "unprognostic (3.89e-1)" "unprognostic (5.93e-3)" "unprognostic (1.77e-3)" "unprognostic (3.23e-1)" "unprognostic (3.05e-1)" "unprognostic (3.25e-2)" "unprognostic (1.06e-1)" "unprognostic (3.76e-1)" "unprognostic (1.40e-1)" "unprognostic (8.60e-3)" 0.3 0.0 0.0 5.0 0.0 0.0 0.8 0.0 0.0 0.3 0.0 18.7 131.1 0.1 67.2 0.0 0.0 0.4 0.0 0.0 0.0 26.1 0.8 0.0 0.0 0.0 0.0 0.2 43.4 0.0 0.0 0.0 0.0 0.3 15.4 0.0 0.3 0.4 0.0 0.0 44.8 0.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.1 1.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 5.0 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 41.6 5.9 9.6 0.0 0.8 0.1 0.1 86.6 0.0 0.0 18.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 123.4 0.0 0.0 0.1 16.1 142.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 110.3 0.2 ROBO4 "ECSM4, FLJ20798, MRB" ENSG00000154133 "Roundabout guidance receptor 4" Q8WZ75 11 124883691-124898500 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Adipocytes: 181.5;Endothelial cells: 119.7;Hepatic stellate cells: 148.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 247.6;TIME: 224.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065212 Approved "Plasma membrane" NA NA 380000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA065212: AB_2685434" "unprognostic (2.86e-1)" "unprognostic (9.35e-2)" "unprognostic (2.67e-1)" "unprognostic (1.07e-1)" "unprognostic (3.82e-2)" "unprognostic (6.97e-2)" "prognostic favorable (4.85e-4)" "unprognostic (7.94e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (1.73e-3)" "unprognostic (2.17e-1)" "unprognostic (1.17e-2)" "prognostic unfavorable (8.73e-4)" "unprognostic (1.55e-1)" "unprognostic (4.63e-1)" "unprognostic (5.15e-2)" 41.4 7.2 11.4 6.6 9.6 0.2 31.8 9.0 9.4 10.0 5.8 6.5 2.9 10.9 2.1 5.5 10.3 9.7 25.8 7.9 9.2 18.5 5.3 34.8 7.8 11.3 10.7 4.1 4.3 4.7 4.6 28.6 11.2 7.0 1.7 0.2 4.1 4.6 13.9 6.9 7.3 9.9 9.5 43.5 6.3 1.4 13.2 1.8 16.7 11.9 2.0 9.4 7.0 8.6 0.4 0.0 0.4 0.0 0.0 1.1 0.1 0.2 3.1 0.7 1.5 0.0 0.0 0.0 23.6 0.1 1.0 0.0 0.0 0.4 1.2 0.0 0.0 0.9 0.0 0.1 0.6 0.0 0.0 0.1 0.0 8.9 3.0 0.4 247.6 0.0 0.0 0.0 8.6 0.0 0.0 0.2 0.0 0.0 3.4 0.0 8.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 224.8 1.2 0.6 0.3 1.1 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 9.6 9.0 9.4 7.9 9.2 11.3 10.7 11.2 9.5 13.2 8.6 181.5 0.0 4.2 2.3 1.6 2.2 1.0 0.2 0.6 0.2 0.6 1.0 3.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.5 0.5 0.2 0.3 119.7 0.0 4.0 0.0 0.2 0.0 5.2 0.0 0.3 2.5 0.6 148.9 1.5 0.1 0.0 0.0 0.0 0.0 8.1 3.7 1.7 4.4 2.8 1.8 20.6 0.1 1.1 0.0 0.5 0.1 0.1 0.0 1.2 2.6 0.3 0.0 0.0 0.0 5.2 0.0 4.5 2.1 0.0 0.1 0.6 1.3 0.0 0.9 2.0 0.1 0.2 SAMD5 dJ875H10.1 ENSG00000203727 "Sterile alpha motif domain containing 5" Q5TGI4 6 147508690-147737547 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Bipolar cells: 96.0;Inhibitory neurons: 276.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 16.6;Hep G2: 65.6;K-562: 44.7;RH-30: 29.0;WM-115: 20.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067811 Uncertain Supported Vesicles No No "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA067811: AB_2685901" "unprognostic (4.16e-2)" "unprognostic (4.52e-2)" "unprognostic (9.65e-3)" "unprognostic (1.41e-2)" "unprognostic (1.82e-2)" "unprognostic (5.88e-2)" "prognostic unfavorable (2.23e-4)" "unprognostic (2.31e-1)" "unprognostic (1.54e-1)" "unprognostic (1.61e-2)" "unprognostic (8.55e-3)" "unprognostic (3.09e-2)" "unprognostic (5.40e-3)" "unprognostic (1.72e-1)" "unprognostic (4.51e-2)" "unprognostic (9.82e-3)" "unprognostic (1.50e-1)" 0.6 1.8 2.8 1.3 5.6 0.1 4.1 1.0 2.6 1.4 0.1 6.0 3.0 4.2 0.8 8.9 0.9 2.2 1.2 2.7 4.0 7.4 7.5 3.4 0.3 8.7 4.1 0.4 1.3 5.7 3.8 12.2 9.1 1.4 8.1 8.9 2.3 2.4 0.2 1.9 4.4 3.1 0.0 1.4 4.5 7.6 7.2 0.1 2.1 0.1 0.7 1.5 1.9 0.8 11.2 1.4 1.4 2.0 0.0 0.0 0.1 3.6 1.3 0.3 0.2 16.6 0.1 0.6 3.6 0.0 0.6 0.1 0.3 2.5 0.4 0.0 2.0 0.8 1.5 65.6 0.2 0.0 1.3 0.0 0.1 0.3 0.1 0.0 6.8 0.0 44.7 0.6 4.8 0.1 0.0 0.0 0.1 8.4 2.8 0.0 29.0 6.5 0.1 2.3 0.5 0.1 0.9 0.2 2.8 0.3 0.0 0.0 4.9 0.5 1.5 0.5 1.3 0.1 1.1 0.0 0.1 0.1 20.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.8 5.6 1.0 2.6 2.7 4.0 8.7 4.1 9.1 0.0 7.2 0.8 1.7 3.2 5.9 1.3 1.0 1.8 5.6 0.5 2.2 96.0 2.9 23.5 2.6 0.0 0.0 18.4 2.1 0.2 0.0 5.4 9.8 2.2 0.5 1.1 10.7 11.1 16.9 0.0 15.7 0.2 0.3 6.9 19.4 1.8 0.0 7.0 6.1 28.1 0.8 0.0 276.9 11.6 0.0 1.0 1.4 1.3 0.3 0.7 0.0 45.0 0.0 9.2 0.0 5.5 0.9 0.6 3.4 3.4 0.1 3.0 5.2 19.7 0.0 4.0 0.0 3.1 2.0 0.5 0.2 36.4 1.6 0.3 0.5 3.6 25.7 4.2 SARDH "DMGDHL1, SDH" ENSG00000123453 "Sarcosine dehydrogenase" Q9UL12 9 133663560-133739955 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "epididymis: 47.9;liver: 114.4;pancreas: 43.2" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 120.6" "Cancer enriched" "Detected in many" 8 "liver cancer: 18.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 3.3;naive CD4 T-cell: 6.7;T-reg: 8.8" "Lineage enriched" "Detected in single" 16 "T-cells: 8.8" "Cell line enhanced" "Detected in many" "AN3-CA: 17.4;Hep G2: 31.1;MOLT-4: 22.5;RH-30: 18.5;RPMI-8226: 39.1;SH-SY5Y: 14.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA057267, HPA058086" Approved Approved Mitochondria NA NA 230000 "Cluster 20: T-cells - T-cell receptor" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA057267: AB_2683388, HPA058086: AB_2683601" "unprognostic (3.64e-2)" "unprognostic (4.87e-2)" "unprognostic (2.31e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (4.62e-4)" "unprognostic (5.83e-2)" "unprognostic (1.42e-3)" "unprognostic (2.21e-1)" "unprognostic (1.58e-1)" "unprognostic (1.43e-1)" "unprognostic (2.23e-1)" "unprognostic (1.74e-1)" "unprognostic (7.74e-3)" "unprognostic (2.78e-1)" "unprognostic (3.48e-1)" "unprognostic (9.73e-2)" "unprognostic (1.30e-2)" 1.1 2.2 3.6 2.5 3.5 0.9 0.8 1.9 3.9 2.6 0.7 1.1 1.8 2.0 47.9 0.6 1.9 1.3 2.4 3.3 3.5 12.0 114.4 2.6 4.1 4.4 3.1 3.0 43.2 2.1 4.1 0.9 3.4 2.3 0.4 0.6 5.3 1.8 0.6 0.4 1.3 0.9 2.9 1.3 3.0 0.7 4.2 4.3 1.6 0.3 2.4 1.1 1.0 3.1 0.0 0.1 1.4 17.4 0.1 0.5 2.3 0.1 0.7 0.9 1.1 0.3 0.2 0.0 2.4 0.3 2.2 0.1 0.0 0.3 0.7 0.0 0.3 2.5 0.0 31.1 1.9 0.1 0.3 4.2 0.0 2.0 0.1 0.4 0.2 13.1 0.1 0.4 11.1 3.2 22.5 2.4 2.8 1.7 0.2 1.6 18.5 39.1 0.0 0.1 1.7 14.7 0.0 0.4 3.9 0.8 2.4 0.2 0.1 3.3 3.0 0.3 0.0 0.3 0.0 1.3 2.1 1.4 0.1 0.3 0.1 0.1 0.3 0.0 0.8 0.0 3.3 0.8 0.0 0.3 6.7 1.2 0.5 0.1 0.0 0.3 8.8 1.4 3.6 3.5 1.9 3.9 3.3 3.5 4.4 3.1 3.4 2.9 4.2 3.1 0.1 0.0 1.9 6.8 0.4 0.3 0.4 0.0 1.2 0.1 0.2 0.8 0.8 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.0 0.8 1.2 5.7 1.5 1.1 0.1 2.3 0.0 0.3 1.3 0.8 2.9 120.6 0.1 0.0 0.7 0.0 0.0 1.6 0.6 0.8 4.7 0.2 0.0 1.9 0.0 4.2 1.0 0.5 0.3 0.1 0.0 3.0 0.7 0.3 0.0 21.3 0.0 0.3 0.0 1.6 3.5 0.1 0.8 0.0 0.1 0.0 4.2 1.6 0.0 0.2 SAT2 SSAT2 ENSG00000141504 "Spermidine/spermine N1-acetyltransferase family member 2" Q96F10 17 7626234-7627876 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 139.8" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 1060.0;Proximal tubular cells: 1313.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022136, HPA057096" Enhanced NA NA 11000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA022136: AB_1856592, HPA057096: AB_2683334" "unprognostic (2.61e-2)" "unprognostic (1.27e-2)" "unprognostic (3.23e-2)" "prognostic favorable (8.76e-6)" "unprognostic (2.18e-2)" "unprognostic (2.32e-1)" "unprognostic (7.20e-2)" "prognostic favorable (6.71e-4)" "unprognostic (4.14e-2)" "unprognostic (2.75e-1)" "prognostic favorable (6.05e-5)" "unprognostic (1.83e-1)" "unprognostic (6.66e-3)" "unprognostic (2.49e-1)" "unprognostic (1.86e-1)" "unprognostic (1.50e-1)" "unprognostic (3.12e-2)" 28.3 102.8 27.7 9.6 28.4 11.3 26.8 28.7 37.5 26.2 32.9 30.5 92.7 25.2 25.1 17.2 26.1 15.8 33.5 27.9 29.2 97.6 139.8 19.0 9.5 28.4 28.5 44.5 47.4 36.0 30.4 8.6 28.3 27.4 15.4 21.1 27.0 16.4 31.8 19.0 65.5 17.1 28.9 29.1 33.4 17.1 29.2 8.0 28.2 20.5 11.8 22.6 19.8 28.8 17.9 27.3 24.1 44.9 37.5 43.6 3.0 12.2 44.3 27.2 33.8 9.3 8.9 3.3 6.8 11.9 30.4 15.3 15.4 11.1 18.0 5.1 41.9 3.6 15.8 49.2 45.3 0.1 12.3 54.6 28.3 16.2 11.9 36.6 39.9 3.5 2.5 5.3 28.8 1.6 0.3 4.1 9.9 10.2 16.6 6.6 11.8 4.2 42.8 20.6 2.6 22.4 11.4 23.4 26.3 21.4 15.5 3.3 17.3 13.2 8.5 0.3 19.3 9.9 9.6 0.7 44.5 5.2 19.7 7.6 41.9 9.5 14.2 28.3 16.7 13.6 12.0 14.6 30.7 12.7 17.8 12.7 2.7 12.4 14.9 14.0 19.5 22.5 27.7 28.4 28.7 37.5 27.9 29.2 28.4 28.5 28.3 28.9 29.2 28.8 70.3 44.8 121.2 76.4 76.2 82.6 90.6 83.2 134.3 121.9 124.1 140.8 62.8 257.4 82.6 80.9 68.8 70.8 68.7 80.4 422.6 135.9 19.4 66.9 79.0 69.8 132.7 25.9 86.2 66.2 33.7 97.3 43.3 59.2 62.1 181.4 114.5 289.0 165.3 129.5 64.6 116.4 124.1 142.7 165.1 28.0 181.7 110.7 94.3 25.3 103.4 156.9 49.4 32.6 36.9 92.8 129.1 119.2 92.9 108.6 1060.0 1313.7 83.9 148.6 72.3 91.2 92.2 30.4 7.8 79.6 56.1 79.2 67.0 321.2 116.8 103.9 SEMA3F "Sema4, SEMAK" ENSG00000001617 "Semaphorin 3F" Q13275 3 50155045-50189075 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 100.8" "Cell type enhanced" "Detected in many" "Adipocytes: 40.2;Bipolar cells: 23.4;Endothelial cells: 24.4;Hepatic stellate cells: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 108.1;HUVEC TERT2: 187.0;RT4: 112.3;SK-BR-3: 170.2;TIME: 338.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035008 Approved "Secreted to blood" NA NA 1700000 7900000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA035008: AB_10604091" "unprognostic (8.17e-2)" "unprognostic (2.01e-1)" "unprognostic (1.12e-2)" "unprognostic (1.87e-2)" "unprognostic (5.52e-3)" "unprognostic (1.71e-1)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.71e-1)" "unprognostic (9.05e-2)" "unprognostic (4.20e-1)" "unprognostic (9.55e-2)" "unprognostic (3.01e-1)" "unprognostic (2.23e-2)" "unprognostic (6.19e-2)" "unprognostic (8.56e-2)" "unprognostic (3.88e-3)" "unprognostic (6.87e-3)" 33.8 9.0 8.8 8.6 5.7 2.7 31.9 5.1 8.1 28.3 12.0 10.5 13.4 14.5 5.4 100.8 15.6 10.8 22.6 5.0 9.2 49.2 4.8 46.2 3.7 10.2 12.7 3.6 6.7 5.5 11.1 30.4 8.7 32.7 6.3 22.0 24.6 32.5 10.4 75.1 12.5 9.1 6.3 50.7 17.3 2.4 21.8 6.1 27.1 6.1 12.6 27.0 55.4 4.7 13.9 3.1 0.7 14.2 0.2 1.3 3.0 8.0 24.2 6.5 10.2 5.4 6.1 0.5 77.9 1.1 0.7 47.5 6.9 100.7 2.4 0.1 1.8 0.8 108.1 18.5 5.7 1.7 3.2 6.2 55.3 15.1 45.4 90.7 187.0 1.2 2.9 0.1 1.3 12.4 1.5 7.5 8.6 6.2 10.1 11.8 0.0 0.5 7.2 112.3 1.1 2.6 12.8 170.2 0.3 10.4 67.2 7.3 338.6 4.2 31.9 29.7 5.5 0.2 0.0 0.9 0.3 4.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 5.7 5.1 8.1 5.0 9.2 10.2 12.7 8.7 6.3 21.8 4.7 40.2 0.0 1.1 0.0 0.2 6.8 3.0 9.2 5.7 23.4 10.7 6.0 9.2 1.5 6.6 18.4 10.4 11.2 0.6 5.5 0.0 0.3 0.0 6.5 2.4 24.4 0.0 0.0 0.7 0.8 0.5 1.1 16.3 6.9 0.0 0.2 25.4 0.6 1.4 6.7 1.1 10.7 0.0 0.3 0.8 0.3 0.3 0.2 0.0 3.7 0.0 8.7 0.0 0.0 0.1 6.8 3.8 0.0 0.0 2.5 5.7 0.7 5.4 19.8 0.0 0.5 2.5 0.0 0.4 17.7 8.9 6.3 0.4 0.2 5.2 8.6 SERPINA6 CBG ENSG00000170099 "Serpin family A member 6" P08185 14 94304248-94323389 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "liver: 776.6" "Group enriched" "Detected in some" 4 "Cholangiocytes: 204.5;Hepatocytes: 390.8" "Cancer enriched" "Detected in many" 9 "liver cancer: 244.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "T-47d: 961.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA017864 Approved "Secreted to blood" NA NA 60800000000 37000000000 "Cluster 62: Liver - Hemostasis" "Cluster 6: T47d - Mammary gland" "Cluster 15: Hepatocytes - Hemostasis" "HPA017864: AB_1856721" "unprognostic (2.82e-2)" "unprognostic (1.67e-1)" "unprognostic (1.02e-3)" "prognostic favorable (6.96e-5)" "unprognostic (2.93e-3)" "unprognostic (9.98e-3)" "unprognostic (4.43e-2)" "unprognostic (3.11e-1)" "unprognostic (4.80e-3)" "unprognostic (2.94e-1)" "unprognostic (2.47e-2)" "unprognostic (4.54e-2)" "unprognostic (1.43e-1)" "unprognostic (2.14e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 1.9 0.0 3.5 0.1 0.5 0.0 0.0 12.6 35.1 0.0 0.0 0.0 43.5 776.6 0.1 0.0 0.0 0.0 0.3 17.4 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 114.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.2 0.4 0.4 4.5 0.1 0.4 0.0 0.1 0.7 0.0 0.0 961.9 0.0 0.0 0.5 0.0 0.6 0.0 0.3 0.0 0.5 1.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.1 0.1 0.1 0.7 0.0 0.0 4.4 0.0 0.4 204.5 0.3 0.0 0.0 0.3 0.0 0.4 1.9 33.1 0.0 62.6 0.3 0.4 9.0 16.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.2 9.7 390.8 0.0 0.0 0.0 0.8 2.0 8.7 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.1 1.0 1.2 0.0 0.0 0.0 0.1 43.0 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 1.8 0.1 SERPINC1 "AT3, ATIII, MGC22579" ENSG00000117601 "Serpin family C member 1" P01008 1 173903800-173917327 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1341 "liver: 5056.6" "Cell type enriched" "Detected in some" 49 "Hepatocytes: 2707.9" "Cancer enriched" "Detected in some" 871 "liver cancer: 1504.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 37 "Hep G2: 84.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001816, CAB016790, HPA024007" Supported "Secreted to blood" NA NA 120000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB016790: , HPA001816: AB_1079926, HPA024007: AB_1856732" "unprognostic (1.28e-2)" "unprognostic (2.22e-1)" "unprognostic (3.83e-2)" "unprognostic (5.98e-2)" "unprognostic (6.91e-2)" "unprognostic (1.93e-2)" "prognostic favorable (3.40e-5)" "unprognostic (1.75e-2)" "unprognostic (8.67e-2)" "unprognostic (3.48e-2)" "unprognostic (4.74e-2)" "unprognostic (1.91e-1)" "unprognostic (2.36e-2)" "unprognostic (5.28e-3)" "unprognostic (5.80e-2)" "unprognostic (6.35e-2)" "unprognostic (8.21e-2)" 0.3 0.1 0.2 0.0 0.3 0.0 0.1 0.3 0.3 0.1 0.2 0.2 0.0 0.0 0.1 0.2 0.1 0.0 0.3 0.3 0.2 3.7 5056.6 0.3 0.1 0.3 0.2 0.1 0.2 0.0 0.2 0.1 0.3 0.1 0.0 0.7 0.1 0.0 0.3 0.1 0.2 0.0 0.2 1.5 0.2 0.4 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.6 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 84.2 0.0 1.6 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.0 0.2 1.8 0.1 0.0 0.1 0.0 0.1 1.2 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.3 0.0 1.0 0.1 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.3 0.3 0.2 0.3 0.2 0.3 0.2 0.2 0.3 0.1 3.2 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 37.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.3 0.2 0.0 1.6 0.0 34.7 0.1 0.4 0.0 0.1 0.0 0.2 0.0 0.1 42.1 2707.9 0.2 0.0 0.1 0.0 0.0 55.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 4.6 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.3 3.7 0.0 0.0 0.2 SERPINF2 "A2AP, AAP, ALPHA-2-PI, API, PLI" ENSG00000167711 "Serpin family F member 2" P08697 17 1742836-1755265 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "liver: 1578.5" "Cell type enriched" "Detected in many" 11 "Hepatocytes: 1007.7" "Cancer enriched" "Detected in all" 6 "liver cancer: 450.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 44.7" "Lineage enriched" "Detected in many" 23 "dendritic cells: 44.7" "Cell line enriched" "Detected in some" 24 "Hep G2: 145.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA001885, CAB024863" Approved "Secreted to blood" NA NA 11900 61000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB024863: , HPA001885: AB_1079922" "unprognostic (2.17e-3)" "unprognostic (2.56e-3)" "unprognostic (2.48e-1)" "unprognostic (7.57e-3)" "unprognostic (3.69e-2)" "unprognostic (1.45e-2)" "prognostic favorable (2.26e-5)" "unprognostic (1.44e-1)" "unprognostic (2.32e-2)" "unprognostic (1.38e-1)" "unprognostic (1.88e-3)" "unprognostic (2.18e-1)" "unprognostic (1.09e-3)" "unprognostic (7.05e-2)" "unprognostic (2.81e-1)" "unprognostic (7.68e-3)" "unprognostic (2.93e-1)" 11.6 2.0 1.4 4.3 1.5 0.4 18.3 1.2 2.2 7.1 11.1 4.2 0.7 8.7 101.4 3.0 19.6 0.7 2.5 2.0 1.4 74.1 1578.5 12.9 3.0 1.6 1.6 7.7 9.2 0.1 1.9 0.8 1.7 21.4 0.5 0.5 6.1 32.6 4.3 5.5 11.6 1.8 1.3 7.1 3.7 12.5 1.8 2.6 7.9 0.4 3.5 7.3 5.8 2.2 1.8 6.1 0.0 0.0 0.5 0.3 0.3 0.0 0.0 0.0 0.0 0.0 3.8 0.3 0.9 0.0 0.3 0.9 0.0 3.3 0.0 0.0 0.0 0.1 0.9 145.9 1.1 0.8 0.1 1.6 1.2 0.0 0.7 0.1 0.0 0.1 0.2 0.2 0.0 0.2 0.0 0.7 0.1 0.3 0.3 0.1 0.9 1.3 0.0 0.3 0.0 0.2 0.6 0.0 1.1 0.0 0.2 0.1 0.3 0.0 0.6 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 1.9 1.4 0.0 0.8 0.0 0.5 0.0 0.0 10.7 0.5 0.0 0.0 0.0 1.2 0.0 44.7 0.0 1.2 1.4 1.5 1.2 2.2 2.0 1.4 1.6 1.6 1.7 1.3 1.8 2.2 1.6 3.2 19.6 0.3 5.3 1.5 4.9 10.3 8.0 0.2 20.5 8.8 0.7 27.1 7.0 1.8 6.2 0.2 32.1 0.7 9.8 0.0 0.6 0.1 2.7 3.4 4.2 23.6 1.6 4.9 0.3 2.7 0.0 0.3 1.3 0.3 14.6 1007.7 7.7 0.0 1.9 2.1 12.2 32.2 20.1 0.8 33.8 8.2 1.8 1.0 10.9 0.1 0.0 1.0 0.7 3.8 2.7 26.7 3.2 2.8 2.2 87.5 4.4 0.4 0.0 1.3 1.2 0.4 0.5 1.3 1.6 0.3 2.6 0.0 3.3 1.8 SFXN2 SLC56A2 ENSG00000156398 "Sideroflexin 2" Q96NB2 10 102714538-102743492 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 17.9;parathyroid gland: 12.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 33.3;Hepatocytes: 21.2;Proximal tubular cells: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "T-47d: 38.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018150, HPA026834" Enhanced Approved Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA018150: AB_1856790, HPA026834: AB_1856791" "unprognostic (1.70e-2)" "prognostic favorable (2.28e-4)" "unprognostic (3.30e-2)" "unprognostic (2.95e-1)" "unprognostic (6.10e-2)" "unprognostic (1.44e-2)" "prognostic favorable (9.95e-4)" "unprognostic (4.24e-2)" "unprognostic (9.69e-2)" "unprognostic (3.98e-2)" "unprognostic (1.32e-1)" "unprognostic (8.98e-3)" "prognostic favorable (2.28e-5)" "unprognostic (1.20e-1)" "unprognostic (2.14e-1)" "unprognostic (3.77e-2)" "prognostic favorable (6.52e-4)" 1.5 1.1 1.2 1.9 2.8 3.0 2.8 3.9 1.7 1.6 3.6 1.9 2.5 2.7 3.6 1.4 3.6 1.1 0.6 1.8 0.8 17.9 4.2 1.6 2.6 1.0 0.5 3.4 3.1 12.7 2.7 3.4 1.2 2.2 3.0 2.7 4.9 1.3 0.7 1.9 1.9 1.1 0.2 2.1 3.3 1.2 1.8 3.2 3.8 0.2 1.9 0.9 0.7 2.1 4.2 2.3 3.5 3.7 1.3 0.9 5.1 1.4 0.6 1.8 0.9 7.2 1.9 9.1 2.7 1.2 1.0 3.0 0.7 4.8 1.0 1.6 2.8 13.1 4.4 4.5 0.6 7.5 1.1 1.0 0.7 1.8 1.8 1.1 1.7 7.7 6.0 4.2 1.1 4.0 11.5 2.5 2.3 4.0 0.8 5.5 4.3 1.3 1.7 3.5 2.6 2.5 1.2 3.1 0.6 1.4 38.4 1.6 1.2 1.4 4.4 1.8 3.1 4.6 6.5 7.9 1.7 9.0 1.2 1.6 0.5 0.2 1.9 0.2 1.7 0.8 1.9 2.0 0.7 2.5 3.0 2.5 0.9 1.9 0.3 1.7 2.0 0.7 1.2 2.8 3.9 1.7 1.8 0.8 1.0 0.5 1.2 0.2 1.8 2.1 1.0 0.0 10.1 5.2 3.8 0.9 3.0 0.8 4.0 6.1 7.3 5.2 2.5 4.3 2.0 1.8 33.3 9.1 2.4 2.5 9.8 1.9 0.8 7.3 4.2 2.2 3.6 4.2 5.4 2.8 4.4 3.2 8.2 10.0 0.0 9.2 5.0 21.2 9.6 0.0 5.5 5.0 0.0 7.5 0.6 0.5 2.1 2.4 0.0 8.4 0.8 1.1 4.1 7.1 2.9 1.4 0.8 1.5 6.7 4.4 2.4 43.1 0.4 15.1 0.0 2.7 1.7 1.2 1.3 3.3 1.3 4.5 2.8 2.6 7.3 2.9 SH2D6 FLJ35993 ENSG00000152292 "SH2 domain containing 6" 2 85418931-85437029 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "intestine: 1.9" "Group enriched" "Detected in some" 5 "Enteroendocrine cells: 10.7;Gastric mucus-secreting cells: 18.3;Proximal tubular cells: 16.7;Spermatocytes: 6.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 13 "LHCN-M2: 1.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA053873 Uncertain NA NA "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA053873: AB_2682286" "unprognostic (4.70e-1)" "unprognostic (3.55e-2)" "unprognostic (3.30e-1)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (2.67e-2)" "unprognostic (7.95e-3)" "unprognostic (1.22e-2)" "unprognostic (1.30e-1)" "unprognostic (1.46e-1)" "unprognostic (2.70e-1)" "unprognostic (2.49e-1)" "unprognostic (5.06e-7)" "unprognostic (2.54e-1)" "unprognostic (8.65e-2)" "unprognostic (1.23e-2)" "unprognostic (5.65e-3)" 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.4 0.0 0.0 0.8 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.2 0.4 0.1 0.2 0.3 0.2 0.3 0.1 0.3 0.4 0.0 0.0 0.0 1.3 0.2 0.0 0.5 0.0 0.0 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 1.9 0.0 0.3 0.1 0.1 0.0 10.7 0.0 0.6 0.0 0.0 0.1 18.3 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.2 2.0 0.0 0.3 0.3 0.4 0.0 0.2 0.0 0.0 0.0 0.4 0.0 1.0 2.4 0.1 2.3 0.4 0.1 0.3 0.6 16.7 0.0 0.2 0.0 0.8 0.2 6.8 2.3 0.0 0.0 0.1 0.3 0.1 1.5 0.0 SH3GL2 "CNSA2, EEN-B1, SH3D2A, SH3P4" ENSG00000107295 "SH3 domain containing GRB2 like 2, endophilin A1" Q99962 9 17579066-17797124 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 123.8;retina: 75.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 89.4;Excitatory neurons: 390.8;Inhibitory neurons: 140.9" "Cancer enhanced" "Detected in many" "glioma: 8.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 9.3;HeLa: 21.1;JURKAT: 18.7;RT4: 41.8;SCLC-21H: 26.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010056, HPA026685, HPA063573" Enhanced Supported Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes No "Cluster 6: Brain - Smell perception" "Cluster 15: RT4 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB010056: AB_628099, HPA026685: AB_1856817, HPA063573: AB_2685045" "unprognostic (4.78e-2)" "unprognostic (3.24e-2)" "unprognostic (1.68e-2)" "unprognostic (5.05e-5)" "unprognostic (4.23e-2)" "unprognostic (3.40e-1)" "unprognostic (1.21e-1)" "unprognostic (5.90e-2)" "unprognostic (3.90e-1)" "unprognostic (5.07e-3)" "unprognostic (8.76e-3)" "unprognostic (1.26e-1)" "prognostic favorable (6.68e-12)" "unprognostic (2.65e-2)" "unprognostic (8.29e-2)" "unprognostic (2.25e-2)" "unprognostic (8.44e-2)" 0.3 0.2 63.0 0.1 69.0 0.0 0.1 92.3 123.8 2.3 1.9 0.5 0.2 2.2 1.2 0.5 2.0 0.0 4.3 77.7 26.6 16.8 0.2 1.1 0.0 27.9 28.5 1.8 3.0 0.3 26.2 0.0 25.9 1.8 0.6 75.0 0.1 0.1 0.1 0.1 0.5 1.7 29.3 0.1 8.7 6.5 41.1 0.7 1.5 0.0 0.0 4.3 0.4 55.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 2.0 7.5 0.8 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 9.3 0.0 21.1 0.0 0.1 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 18.7 0.0 0.1 0.0 0.0 0.1 0.2 2.5 0.0 2.4 0.0 0.0 0.0 0.0 41.8 26.5 0.0 0.3 0.0 0.8 0.8 0.0 0.0 0.0 0.0 2.2 0.0 1.5 0.0 0.4 0.0 1.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 63.0 69.0 92.3 123.8 77.7 26.6 27.9 28.5 25.9 29.3 41.1 55.5 0.0 0.0 0.0 16.3 0.0 0.1 0.4 0.0 0.0 89.4 0.1 0.0 1.8 0.0 0.0 7.3 22.9 0.0 0.0 0.1 11.7 0.0 16.7 0.2 0.1 0.3 5.3 0.0 390.8 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.1 13.5 140.9 0.7 0.0 0.0 0.3 47.4 1.2 0.1 0.0 13.1 0.1 9.0 0.0 41.7 10.2 0.2 0.1 0.4 0.0 2.2 0.0 22.2 0.0 28.0 0.0 0.0 0.1 2.4 6.1 0.0 0.0 0.1 0.0 1.2 0.7 0.4 SHBG "ABP, MGC126834, MGC138391, TEBG" ENSG00000129214 "Sex hormone binding globulin" P04278 17 7613946-7633382 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 63.4" "Cell type enhanced" "Detected in some" "Early spermatids: 51.6;Late spermatids: 124.5;Proximal enterocytes: 31.1" "Cancer enriched" "Detected in some" 28 "liver cancer: 14.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 4.4;Hep G2: 3.0;HSkMC: 4.3" "Not detected" "Not detected" "Secreted to blood" NA NA 9100000000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (3.35e-3)" "unprognostic (6.47e-2)" "unprognostic (5.65e-2)" "unprognostic (2.35e-1)" "unprognostic (8.84e-2)" "unprognostic (3.08e-1)" "unprognostic (3.50e-1)" "unprognostic (2.27e-1)" "unprognostic (6.55e-2)" "unprognostic (1.32e-3)" "unprognostic (3.58e-3)" "unprognostic (2.21e-1)" "unprognostic (4.49e-2)" "unprognostic (7.83e-3)" "unprognostic (4.35e-1)" "unprognostic (5.50e-3)" "unprognostic (1.06e-1)" 0.7 1.3 1.8 0.0 1.8 0.1 0.4 1.7 2.0 0.7 1.9 0.3 5.3 0.5 0.9 0.2 0.6 0.3 0.6 1.9 1.8 3.5 63.4 0.3 0.1 1.8 1.8 0.7 0.4 0.5 0.7 0.3 1.9 0.5 0.2 0.9 0.2 0.4 0.8 0.1 7.1 0.2 1.7 0.4 0.3 12.4 1.7 0.2 0.8 0.7 0.1 0.3 0.2 1.8 0.1 2.4 2.4 0.3 4.4 2.0 0.1 0.6 0.9 0.9 0.5 0.9 0.3 0.0 0.5 0.8 1.2 0.3 0.1 0.1 0.5 0.1 0.3 0.0 0.6 3.0 1.4 0.0 0.1 4.3 0.3 1.6 0.8 0.8 0.1 0.0 0.2 0.1 0.2 0.5 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.3 0.3 0.3 0.1 0.3 1.8 0.0 0.2 0.8 0.4 0.0 0.8 0.4 0.0 0.0 0.2 0.3 0.3 0.2 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.8 1.7 2.0 1.9 1.8 1.8 1.8 1.9 1.7 1.7 1.8 0.2 0.0 0.0 0.7 0.5 0.0 0.3 0.1 0.0 0.4 0.5 0.6 0.5 0.0 0.2 0.0 0.0 0.4 0.0 0.2 5.9 0.5 51.6 0.4 0.6 0.1 0.0 0.0 1.0 0.2 0.1 0.4 0.0 0.2 0.0 0.6 1.1 13.8 0.3 0.0 0.9 1.3 2.0 0.8 0.0 124.5 0.9 0.5 0.0 0.0 0.0 2.4 0.0 0.5 0.6 0.1 1.3 0.7 0.0 0.3 31.1 12.8 0.4 1.3 6.6 0.2 0.3 7.2 0.8 0.0 0.0 0.3 0.1 1.1 0.5 0.3 SHISA2 "bA398O19.2, C13orf13, hShisa, PRO28631, TMEM46, WGAR9166" ENSG00000180730 "Shisa family member 2" Q6UWI4 13 26044597-26052016 "Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 12.4;skeletal muscle: 14.2;thyroid gland: 21.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 13.1;Basal prostatic cells: 14.6;Breast glandular cells: 24.1;Oligodendrocytes: 10.9;Urothelial cells: 19.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 25.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 26.7;JURKAT: 20.8;LHCN-M2: 18.7;NTERA-2: 15.5;RH-30: 46.3;U-2197: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA049752, HPA050172" Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "Nuclear bodies, Vesicles" "HPA049752: , HPA050172: AB_2681041" "unprognostic (2.08e-2)" "unprognostic (3.00e-1)" "unprognostic (2.41e-1)" "unprognostic (9.71e-2)" "unprognostic (6.09e-2)" "unprognostic (2.52e-1)" "unprognostic (1.20e-1)" "prognostic favorable (3.30e-4)" "unprognostic (4.03e-2)" "unprognostic (3.10e-1)" "unprognostic (7.45e-2)" "unprognostic (2.17e-2)" "prognostic favorable (2.43e-4)" "unprognostic (5.56e-3)" "unprognostic (2.09e-1)" "unprognostic (3.46e-1)" "unprognostic (1.51e-2)" 0.5 0.0 1.1 0.2 2.3 0.1 12.4 1.5 2.0 1.7 0.9 0.1 0.7 0.1 7.8 0.2 0.2 0.5 0.2 2.0 1.5 4.7 0.0 4.3 0.5 1.9 1.5 0.3 0.3 0.1 1.6 0.0 1.6 0.5 0.1 0.0 2.7 0.3 14.2 1.1 0.7 0.1 2.2 0.2 2.1 1.2 1.6 2.5 21.0 1.2 0.7 0.7 0.0 5.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.8 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.4 4.2 1.4 0.0 0.0 1.7 26.7 1.0 20.8 0.0 0.0 18.7 1.2 2.3 0.5 15.5 8.4 8.2 0.0 46.3 0.3 1.7 6.5 0.4 0.0 0.4 0.0 5.4 2.6 0.7 0.2 1.6 0.1 0.7 30.4 7.0 0.0 0.0 0.0 0.0 0.0 4.1 0.8 0.1 0.5 0.1 0.2 0.2 0.1 0.4 0.1 0.0 0.2 1.0 1.6 0.4 0.2 0.3 0.1 0.2 0.1 1.1 2.3 1.5 2.0 2.0 1.5 1.9 1.5 1.6 2.2 1.6 5.4 4.7 0.0 13.1 0.0 0.4 5.4 14.6 2.3 0.6 0.0 24.1 6.2 0.5 0.0 1.5 3.7 0.0 0.3 0.3 0.1 0.0 6.0 2.6 1.0 0.5 5.1 0.0 0.0 0.0 0.2 0.3 2.8 3.1 2.5 0.0 2.4 1.1 0.0 0.8 0.0 1.0 0.1 8.2 0.3 2.3 1.0 0.0 0.3 1.8 0.0 0.0 0.0 0.0 0.5 10.9 1.2 0.0 0.4 0.2 3.9 0.0 0.3 1.1 0.0 0.0 7.6 1.6 0.7 5.1 0.4 1.7 0.1 1.1 0.7 0.0 19.6 SHMT1 "CSHMT, MGC15229, MGC24556, SHMT" ENSG00000176974 "Serine hydroxymethyltransferase 1" P34896 17 18327860-18363563 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 168.5;liver: 398.7" "Group enriched" "Detected in many" 4 "Hepatocytes: 307.7;Proximal tubular cells: 435.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023314, HPA078682" Enhanced Supported Nucleoplasm,Cytosol NA NA 1500000 "Cluster 44: Non-specific - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA023314: AB_1856830, HPA078682: " "unprognostic (4.76e-2)" "unprognostic (1.98e-2)" "unprognostic (5.46e-2)" "unprognostic (3.76e-1)" "unprognostic (2.45e-1)" "unprognostic (8.44e-3)" "prognostic favorable (2.52e-4)" "unprognostic (7.55e-3)" "unprognostic (4.50e-1)" "unprognostic (2.42e-1)" "unprognostic (2.14e-1)" "unprognostic (1.70e-1)" "prognostic favorable (8.54e-6)" "unprognostic (1.70e-2)" "unprognostic (2.66e-1)" "unprognostic (2.57e-3)" "unprognostic (4.04e-2)" 37.5 9.4 8.1 4.0 9.4 9.5 36.3 12.6 9.5 13.6 7.1 17.5 13.8 7.6 4.9 59.2 13.1 7.7 5.7 8.8 8.5 168.5 398.7 10.3 9.0 10.8 9.3 11.7 8.8 85.7 4.1 7.7 10.7 10.1 6.1 3.1 30.0 10.0 18.8 22.6 24.4 3.7 8.0 21.7 13.3 12.8 9.4 21.1 23.5 18.6 17.6 11.5 19.3 16.0 39.6 28.9 5.5 34.5 29.9 15.8 63.0 11.3 10.3 30.8 31.2 22.1 22.5 26.8 27.8 3.6 16.4 18.8 32.4 39.7 24.3 17.3 30.6 13.0 39.9 21.6 7.2 4.4 11.0 21.1 13.6 23.1 7.2 10.9 9.7 32.3 10.0 10.9 11.3 12.4 46.0 13.9 17.4 43.6 5.1 29.7 48.5 34.7 69.3 17.0 24.0 5.3 82.7 14.9 21.4 50.2 64.5 19.4 2.6 5.7 14.0 71.4 17.6 10.7 20.5 7.1 10.3 12.7 16.5 10.2 4.7 5.2 5.3 5.9 8.1 4.4 6.6 5.5 3.5 3.7 6.8 6.4 0.2 8.5 5.2 1.1 11.2 4.3 8.1 9.4 12.6 9.5 8.8 8.5 10.8 9.3 10.7 8.0 9.4 16.0 11.2 12.8 31.0 3.3 10.4 10.3 21.7 16.5 18.8 3.1 22.7 13.8 2.7 42.9 11.2 36.8 4.2 23.7 5.2 8.9 82.2 13.7 10.9 6.2 1.9 7.4 1.2 28.0 5.2 7.7 76.1 8.0 9.2 10.1 8.2 9.9 13.6 307.7 39.6 0.0 4.8 12.9 4.1 36.8 3.5 5.5 5.9 17.2 12.4 9.4 4.4 33.8 5.2 2.0 11.4 5.3 9.7 3.0 20.3 5.9 53.7 435.7 3.5 4.2 19.7 8.1 4.4 30.0 21.4 35.4 10.5 8.5 10.1 4.9 32.2 10.9 SIGLEC9 CD329 ENSG00000129450 "Sialic acid binding Ig like lectin 9" Q9Y336 19 51124906-51136651 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.7" "Cell type enhanced" "Detected in some" "Hofbauer cells: 42.1;Kupffer cells: 39.8;Langerhans cells: 13.4;Macrophages: 26.8;monocytes: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 198.9;intermediate monocyte: 182.5;myeloid DC: 169.1;neutrophil: 212.0;non-classical monocyte: 121.9" "Group enriched" "Detected in many" 13 "dendritic cells: 169.1;granulocytes: 212.0;monocytes: 198.9" "Group enriched" "Detected in some" 10 "Karpas-707: 23.4;RPMI-8226: 16.5" HPA010682 Uncertain NA NA 270000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA010682: AB_1079968" "unprognostic (2.31e-1)" "unprognostic (3.99e-2)" "unprognostic (1.03e-2)" "unprognostic (1.36e-1)" "unprognostic (4.69e-2)" "unprognostic (6.86e-2)" "unprognostic (5.10e-2)" "unprognostic (2.10e-1)" "unprognostic (1.31e-1)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (7.03e-3)" "prognostic unfavorable (6.17e-5)" "unprognostic (6.56e-2)" "unprognostic (7.38e-3)" "unprognostic (2.95e-1)" "unprognostic (1.73e-1)" 8.0 5.4 2.0 17.9 2.1 9.0 1.9 2.2 4.3 1.4 2.8 2.1 1.7 0.9 0.2 0.9 2.5 5.0 2.1 1.9 3.4 1.4 5.5 8.3 5.0 5.4 4.0 3.2 1.2 4.1 0.9 7.9 5.0 1.1 2.4 0.3 1.5 0.9 0.4 0.5 2.2 6.4 4.0 20.7 1.4 1.7 6.2 1.4 0.9 1.3 2.5 5.4 0.8 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 23.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 2.0 1.5 0.0 17.3 198.9 1.6 15.2 182.5 8.6 0.2 2.5 5.8 169.1 0.1 0.6 2.7 212.0 3.1 121.9 9.2 0.9 84.9 2.0 2.1 2.2 4.3 1.9 3.4 5.4 4.0 5.0 4.0 6.2 5.9 0.1 0.0 0.5 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 1.3 0.0 0.0 0.2 2.7 0.0 0.0 0.0 1.8 0.0 0.1 1.1 0.0 0.0 0.2 0.0 0.4 0.5 0.0 0.0 0.0 0.1 5.3 0.8 42.1 0.0 0.2 0.0 0.0 39.8 13.4 0.4 5.0 26.8 0.0 5.6 10.4 0.0 7.2 0.0 0.1 0.0 0.0 2.2 0.4 0.0 0.0 0.1 0.0 0.0 6.6 0.0 0.1 0.0 0.1 0.0 0.1 0.3 1.3 2.8 0.0 0.0 SLC10A2 "ASBT, ISBT" ENSG00000125255 "Solute carrier family 10 member 2" Q12908 13 103043998-103066417 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 80.8" "Cell type enriched" "Detected in some" 29 "Proximal enterocytes: 371.2" "Cancer enriched" "Detected in single" 11 "renal cancer: 4.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA004795 Approved NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 45: Enterocytes - Digestion" "HPA004795: AB_1856953" "unprognostic (2.82e-2)" "prognostic favorable (5.78e-5)" "unprognostic (1.64e-2)" "unprognostic (1.29e-1)" 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.3 0.2 0.0 0.0 0.4 23.8 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 16.9 0.0 0.1 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 80.8 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 0.0 0.2 0.5 0.3 0.5 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 371.2 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.1 SLC13A1 "NAS1, NaSi-1" ENSG00000081800 "Solute carrier family 13 member 1" Q9BZW2 7 123113531-123199972 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sulfate transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "kidney: 81.9" "Cell type enriched" "Detected in some" 6 "Proximal tubular cells: 452.1" "Cancer enriched" "Detected in single" 219 "renal cancer: 10.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA053615, HPA062714" Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA053615: AB_2682207, HPA062714: AB_2684846" "unprognostic (1.86e-1)" "prognostic favorable (8.95e-5)" "unprognostic (1.71e-1)" "unprognostic (3.76e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 81.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 7.3 0.0 0.0 0.0 0.1 27.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.1 0.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 75.3 452.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 4.1 0.0 SLC13A2 NaDC-1 ENSG00000007216 "Solute carrier family 13 member 2" Q13183 17 28473293-28497781 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 119.6;kidney: 38.2;salivary gland: 44.9" "Group enriched" "Detected in some" 6 "Proximal enterocytes: 290.2;Proximal tubular cells: 97.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA014963 Enhanced NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA014963: AB_1857096" "unprognostic (8.47e-2)" "unprognostic (7.63e-3)" "unprognostic (4.36e-3)" "unprognostic (2.06e-1)" "unprognostic (2.36e-3)" "unprognostic (3.06e-1)" "unprognostic (2.28e-4)" "unprognostic (1.50e-1)" "unprognostic (1.74e-1)" "unprognostic (1.00e-2)" "prognostic favorable (9.00e-4)" "unprognostic (2.16e-1)" "unprognostic (2.64e-1)" "unprognostic (1.50e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.7 6.1 119.6 0.0 3.0 0.0 0.0 6.8 0.0 0.0 0.0 38.2 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.8 0.8 44.9 11.4 0.0 3.1 90.8 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.8 0.0 0.0 13.7 10.9 0.6 27.1 1.6 3.7 12.5 0.0 0.7 29.3 9.8 0.7 0.0 0.0 0.0 0.2 4.8 0.0 0.1 7.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 31.4 0.0 0.0 0.4 0.0 0.0 0.7 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.2 15.7 0.0 0.0 0.0 290.2 97.8 0.3 0.4 0.0 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.5 0.0 25.8 0.5 SLC13A3 "NADC3, SDCT2" ENSG00000158296 "Solute carrier family 13 member 3" Q8WWT9 20 46557823-46684467 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "kidney: 407.6" "Cell type enhanced" "Detected in many" "Astrocytes: 53.8;Cytotrophoblasts: 106.6;Excitatory neurons: 65.0;Oligodendrocytes: 178.1;Proximal tubular cells: 245.9;Syncytiotrophoblasts: 79.4" "Cancer enhanced" "Detected in many" "liver cancer: 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 16.1;EFO-21: 18.8;Hep G2: 56.1;HHSteC: 18.4;K-562: 15.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014333, HPA014353, HPA014736" Enhanced Supported "Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA014333: AB_2732407, HPA014353: AB_1856968, HPA014736: AB_1856970" "unprognostic (1.07e-2)" "unprognostic (7.40e-2)" "unprognostic (5.59e-2)" "unprognostic (1.19e-2)" "unprognostic (3.34e-1)" "unprognostic (3.19e-2)" "unprognostic (2.15e-1)" "unprognostic (2.82e-2)" "unprognostic (1.66e-2)" "unprognostic (9.50e-2)" "unprognostic (1.92e-2)" "unprognostic (1.03e-1)" "unprognostic (8.94e-2)" "unprognostic (3.87e-1)" "unprognostic (1.17e-1)" "unprognostic (1.87e-1)" "unprognostic (2.05e-2)" 1.3 2.4 12.5 0.7 22.8 0.2 1.9 16.5 16.1 2.0 4.9 0.8 0.3 1.8 1.0 0.9 2.4 1.9 1.0 10.1 16.2 407.6 21.7 1.4 0.6 18.3 19.5 4.5 9.0 0.2 2.6 43.2 19.0 6.3 0.5 1.1 4.9 0.8 1.0 2.2 0.4 1.9 12.5 0.6 4.7 8.7 19.9 1.1 1.4 0.3 0.7 1.8 1.4 37.4 0.1 0.0 1.6 5.6 8.3 7.7 16.1 3.5 2.0 1.9 1.4 0.0 0.1 0.2 18.8 0.2 0.1 2.1 0.1 2.6 4.5 0.0 0.6 6.8 0.4 56.1 18.4 0.1 4.8 10.5 7.5 10.9 5.4 5.4 0.0 0.0 15.3 0.3 0.0 0.6 0.1 0.7 10.3 0.2 0.0 0.2 0.0 0.1 1.2 0.4 0.7 0.2 0.0 4.0 0.8 1.0 2.9 0.3 0.2 0.1 4.0 8.7 0.1 0.5 1.2 0.1 0.6 0.0 0.4 0.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.5 0.0 0.0 12.5 22.8 16.5 16.1 10.1 16.2 18.3 19.5 19.0 12.5 19.9 37.4 0.3 0.0 2.2 53.8 3.8 1.3 1.0 0.8 6.2 0.7 1.2 1.7 1.7 0.0 0.5 7.3 0.0 106.6 0.0 0.1 15.6 0.2 23.3 0.5 2.0 0.6 0.0 0.0 65.0 0.9 7.1 2.3 3.1 0.8 0.0 3.0 0.4 17.5 9.5 0.0 40.3 0.0 0.0 0.3 0.7 27.8 3.1 2.0 0.0 11.2 0.0 0.4 0.0 24.1 178.1 0.9 0.0 0.4 1.2 3.5 0.0 245.9 6.4 0.2 0.0 0.4 1.0 6.6 1.2 1.2 0.6 79.4 1.5 2.2 0.0 0.6 SLC16A9 "C10orf36, FLJ43803, MCT9" ENSG00000165449 "Solute carrier family 16 member 9" Q7RTY1 10 59650764-59736002 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 151.3;kidney: 191.1" "Group enriched" "Detected in many" 4 "Astrocytes: 83.9;Distal enterocytes: 108.6;Proximal tubular cells: 252.6;Theca cells: 99.4" "Cancer enhanced" "Detected in many" "renal cancer: 21.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 10.8;NTERA-2: 20.1;SuSa: 10.1;U-251 MG: 10.6;U-937: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049286 Approved Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Cell Junctions" "HPA049286: AB_2680699" "unprognostic (3.39e-2)" "unprognostic (6.91e-2)" "unprognostic (1.30e-1)" "unprognostic (1.27e-1)" "unprognostic (1.60e-3)" "unprognostic (1.76e-2)" "unprognostic (5.96e-2)" "unprognostic (3.50e-3)" "unprognostic (5.01e-2)" "unprognostic (2.11e-3)" "unprognostic (5.99e-2)" "unprognostic (4.60e-2)" "prognostic favorable (2.56e-6)" "unprognostic (7.57e-3)" "unprognostic (1.27e-2)" "unprognostic (3.72e-1)" "unprognostic (1.94e-1)" 1.2 151.3 12.8 1.2 12.8 1.7 1.7 11.9 14.8 18.5 18.4 12.5 0.4 16.2 5.2 10.9 22.0 3.1 3.4 12.9 16.6 191.1 2.5 1.1 1.7 14.0 13.7 34.1 3.0 29.2 6.9 0.1 12.0 7.8 16.7 5.6 2.9 10.2 4.3 0.4 1.2 7.2 13.3 40.8 6.0 8.9 12.3 1.2 13.9 2.8 2.8 2.2 9.0 15.0 0.0 0.3 5.2 6.8 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.3 0.0 0.7 0.0 0.0 0.9 10.8 0.0 0.0 0.0 1.8 0.1 0.3 0.1 0.1 2.3 0.0 0.5 0.2 0.0 2.8 0.1 0.4 5.4 8.0 0.1 0.6 4.2 3.0 0.0 20.1 2.0 9.3 3.6 0.2 7.2 0.0 0.3 3.4 9.6 0.1 0.4 0.0 10.1 3.4 4.5 3.2 0.5 1.1 0.1 10.6 0.0 0.0 0.0 0.0 18.6 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 12.8 11.9 14.8 12.9 16.6 14.0 13.7 12.0 13.3 12.3 15.0 0.3 0.0 0.0 83.9 1.0 0.1 2.1 9.4 0.6 4.3 3.1 1.5 3.9 0.0 26.2 7.3 0.0 0.0 0.0 108.6 25.4 1.0 0.2 2.3 2.0 1.5 20.0 4.2 2.5 0.0 1.7 4.1 3.6 2.4 0.0 28.4 0.4 0.0 0.1 3.3 4.8 19.1 4.1 18.8 0.7 1.5 13.7 1.5 3.6 1.9 0.6 11.8 0.0 14.6 1.0 0.1 23.2 12.0 0.0 17.7 2.2 252.6 7.4 1.0 0.0 2.4 3.4 0.3 0.2 17.0 0.1 0.0 0.7 99.4 11.9 6.5 SLC17A1 "NAPI-1, NPT1" ENSG00000124568 "Solute carrier family 17 member 1" Q14916 6 25782915-25832052 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 49 "kidney: 169.3;liver: 49.4" "Cell type enhanced" "Detected in some" "Early spermatids: 13.5;Hepatocytes: 10.3;Proximal tubular cells: 49.2" "Group enriched" "Detected in some" 150 "liver cancer: 7.6;renal cancer: 19.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 647 "RPTEC TERT1: 64.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA050513 Approved "Golgi apparatus" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "HPA050513: AB_2681152" "unprognostic (6.98e-2)" "unprognostic (2.99e-1)" "unprognostic (1.03e-1)" "unprognostic (1.26e-1)" "unprognostic (2.71e-3)" "unprognostic (1.32e-1)" "unprognostic (2.37e-1)" "unprognostic (4.74e-1)" 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 169.3 49.4 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 49.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 SLC17A3 NPT4 ENSG00000124564 "Solute carrier family 17 member 3" O00476 6 25833066-25882286 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 164.3" "Cell type enriched" "Detected in some" 13 "Proximal tubular cells: 197.8" "Cancer enriched" "Detected in some" 17 "renal cancer: 57.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 210 "RPTEC TERT1: 114.7" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (5.31e-3)" "unprognostic (1.56e-2)" "unprognostic (2.51e-1)" "unprognostic (4.65e-2)" "unprognostic (5.05e-2)" "unprognostic (1.88e-1)" "unprognostic (1.07e-1)" "unprognostic (2.34e-1)" "unprognostic (1.34e-1)" "unprognostic (4.49e-1)" 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 164.3 37.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 114.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 1.5 0.0 1.8 0.0 0.0 0.2 0.1 7.9 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.1 15.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 197.8 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.8 0.2 0.0 0.1 SLC22A11 OAT4 ENSG00000168065 "Solute carrier family 22 member 11" Q9NSA0 11 64555690-64572875 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 72 "epididymis: 10.6;kidney: 31.9;placenta: 33.4" "Group enriched" "Detected in some" 19 "Cytotrophoblasts: 654.0;Syncytiotrophoblasts: 1520.6" "Cancer enriched" "Detected in some" 4 "renal cancer: 15.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.3;Hep G2: 1.0" "Not detected" "Not detected" HPA026076 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA026076: AB_1854756" "unprognostic (8.21e-5)" "unprognostic (3.29e-2)" "unprognostic (3.57e-1)" "unprognostic (1.57e-1)" "unprognostic (3.20e-2)" "unprognostic (4.57e-3)" "unprognostic (3.48e-1)" "unprognostic (1.93e-1)" "unprognostic (4.86e-2)" "unprognostic (4.51e-2)" "unprognostic (7.56e-2)" "unprognostic (1.13e-1)" "prognostic favorable (3.68e-5)" "unprognostic (4.62e-2)" "unprognostic (6.52e-2)" "unprognostic (3.50e-2)" "unprognostic (8.24e-3)" 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 31.9 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 33.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 0.0 0.0 0.0 0.0 654.0 0.0 0.0 5.9 0.0 1.2 0.0 0.2 1.7 0.0 0.0 0.0 0.4 22.5 3.4 0.0 0.0 0.0 0.0 0.4 0.2 50.3 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.3 0.3 0.0 1.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.8 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 1520.6 0.2 0.1 0.2 0.0 SLC22A12 "OAT4L, RST, URAT1" ENSG00000197891 "Solute carrier family 22 member 12" Q96S37 11 64590641-64602353 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 204 "kidney: 109.4" "Cell type enriched" "Detected in some" 17 "Proximal tubular cells: 173.1" "Cancer enriched" "Detected in some" 4 "renal cancer: 16.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA024575 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA024575: AB_1858650" "unprognostic (5.88e-2)" "unprognostic (2.33e-1)" "prognostic favorable (2.63e-4)" "unprognostic (6.19e-2)" "unprognostic (3.91e-2)" 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.5 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 109.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.8 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 173.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 SLC22A13 "OAT10, OCTL1, OCTL3, ORCTL3" ENSG00000172940 "Solute carrier family 22 member 13" Q9Y226 3 38265812-38278757 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "kidney: 9.0" "Group enriched" "Detected in some" 12 "Excitatory neurons: 2.3;Inhibitory neurons: 1.8;Proximal tubular cells: 7.1" "Cancer enriched" "Detected in single" 7 "renal cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA035603, HPA035962" Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA035603: AB_10672869, HPA035962: AB_2674890" "unprognostic (2.73e-2)" "unprognostic (6.70e-2)" "unprognostic (2.80e-1)" "unprognostic (5.68e-2)" "unprognostic (7.13e-3)" "unprognostic (3.50e-3)" "unprognostic (6.83e-2)" "unprognostic (1.49e-1)" "unprognostic (3.48e-1)" "unprognostic (2.09e-1)" "unprognostic (3.04e-1)" "unprognostic (1.92e-1)" "unprognostic (8.65e-5)" "unprognostic (3.39e-1)" "unprognostic (1.96e-2)" "unprognostic (5.24e-2)" "unprognostic (2.74e-1)" 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.1 0.1 0.4 0.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLC22A18AS "BWR1B, BWSCR1B, ORCTL2S, p27-BWR1B, SLC22A1LS" ENSG00000254827 "Solute carrier family 22 member 18 antisense" Q8N1D0 11 2887344-2903575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 17.7;kidney: 11.1;liver: 14.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 163.3;Paneth cells: 124.4;Proximal enterocytes: 75.7;Proximal tubular cells: 104.0;Syncytiotrophoblasts: 80.7;Undifferentiated cells: 48.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 7.0" "Group enriched" "Detected in many" 8 "dendritic cells: 3.9;granulocytes: 4.0;monocytes: 7.0" "Cell line enhanced" "Detected in some" "A549: 9.4;CAPAN-2: 9.4;MCF7: 18.8;OE19: 8.4;SK-MEL-30: 35.8;WM-115: 14.8" HPA068288 Enhanced Approved Nucleoplasm No NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA068288: AB_2685969" "unprognostic (1.43e-1)" "unprognostic (9.21e-2)" "unprognostic (3.36e-1)" "unprognostic (8.05e-2)" "unprognostic (1.33e-3)" "unprognostic (3.16e-2)" "unprognostic (5.14e-3)" "unprognostic (9.76e-2)" "unprognostic (1.45e-1)" "unprognostic (2.73e-1)" "unprognostic (1.10e-2)" "unprognostic (1.48e-2)" "unprognostic (9.52e-2)" "unprognostic (1.77e-1)" "unprognostic (2.39e-1)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" 3.2 0.6 0.5 2.2 0.6 0.2 0.7 0.5 1.7 0.7 0.5 17.7 13.4 0.8 0.4 1.2 0.4 1.7 0.3 0.6 1.0 11.1 14.9 0.6 0.4 0.9 0.9 0.4 0.3 0.0 0.3 2.3 1.1 0.8 10.2 0.3 1.8 0.1 0.1 1.1 9.7 0.7 0.8 0.7 1.6 0.5 0.8 0.1 0.3 0.0 0.1 0.7 0.9 1.1 1.2 9.4 0.3 0.5 0.0 0.0 0.9 0.5 0.4 0.0 0.2 2.2 9.4 0.0 0.8 0.0 0.6 0.5 0.0 0.3 0.0 0.4 0.1 0.0 0.8 5.8 0.7 0.0 0.1 0.1 0.3 0.0 0.6 0.4 0.3 0.5 0.0 0.9 0.0 18.8 0.0 0.4 0.2 8.4 0.3 0.3 0.0 1.0 0.8 0.0 0.1 0.3 0.9 0.4 35.8 0.2 0.0 0.9 1.9 0.0 0.7 0.3 0.2 0.0 0.0 0.2 0.2 2.6 14.8 4.0 7.0 1.2 0.2 3.9 0.1 0.0 0.1 0.2 3.9 0.0 0.0 0.1 1.6 0.4 2.9 0.0 0.6 2.4 0.5 0.6 0.5 1.7 0.6 1.0 0.9 0.9 1.1 0.8 0.8 1.1 0.6 0.0 0.5 0.0 1.3 0.5 1.1 6.3 1.2 0.0 1.2 0.9 0.4 1.5 2.7 7.3 0.0 19.5 0.4 163.3 9.8 1.7 0.1 0.1 0.3 0.7 9.1 3.2 0.4 0.8 9.8 1.4 2.6 0.5 1.3 0.0 2.9 22.7 17.7 0.0 0.1 26.2 6.1 6.3 5.5 0.2 0.3 6.4 3.6 0.0 4.6 0.0 0.0 0.0 0.1 2.4 124.4 0.0 0.0 1.0 75.7 104.0 1.0 0.0 0.0 0.0 0.6 0.1 0.4 2.1 1.1 80.7 0.9 0.8 48.5 2.5 SLC22A24 "MGC34821, NET46" ENSG00000197658 "Solute carrier family 22 member 24" Q8N4F4 11 63079940-63144221 "Predicted membrane proteins" "Ion transport, Lipid metabolism, Steroid metabolism, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 1.1;kidney: 4.4" "Group enriched" "Detected in some" 5 "Excitatory neurons: 5.9;Proximal tubular cells: 11.8" "Cancer enriched" "Detected in single" 11 "renal cancer: 0.5" "Region enhanced" "Detected in single" "cerebral cortex: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045015 Uncertain NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA045015: AB_2679183" "unprognostic (5.72e-3)" "unprognostic (1.80e-7)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 4.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 1.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLC22A6 "OAT1, PAHT, ROAT1" ENSG00000197901 "Solute carrier family 22 member 6" Q4U2R8 11 62936385-62984967 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 26 "kidney: 196.5" "Cell type enriched" "Detected in some" 17 "Proximal tubular cells: 310.4" "Cancer enriched" "Detected in single" 102 "renal cancer: 18.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA074559, CAB075704" Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB075704: , HPA074559: AB_2732260" "unprognostic (2.42e-2)" "unprognostic (2.25e-3)" "unprognostic (4.43e-1)" 0.0 0.0 1.3 0.0 2.5 0.0 0.0 3.6 2.3 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 3.8 196.5 0.0 0.0 0.0 7.0 5.5 0.0 0.0 0.0 0.6 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.1 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.5 3.6 2.3 1.3 3.8 7.0 5.5 3.1 3.3 7.6 1.2 0.0 0.0 0.0 4.9 1.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 7.3 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.3 0.0 1.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 310.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 SLC22A7 "NLT, OAT2" ENSG00000137204 "Solute carrier family 22 member 7" Q9Y694 6 43295694-43305538 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "liver: 427.9" "Group enriched" "Detected in some" 17 "Hepatocytes: 254.5;Proximal tubular cells: 91.8" "Cancer enriched" "Detected in some" 37 "liver cancer: 81.5" "Region enhanced" "Detected in single" "cerebellum: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 20 "Hep G2: 9.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA030220 Approved NA NA "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA030220: AB_10603027" "unprognostic (9.17e-2)" "unprognostic (9.73e-4)" "unprognostic (2.13e-1)" "prognostic favorable (5.48e-6)" "unprognostic (1.45e-1)" "unprognostic (1.54e-3)" "unprognostic (1.74e-2)" "prognostic favorable (8.98e-4)" "unprognostic (1.29e-1)" "unprognostic (1.07e-1)" 0.0 0.0 0.3 0.0 0.4 0.0 0.0 1.5 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 47.6 427.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 1.5 0.6 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.1 9.8 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 254.5 0.0 0.0 0.7 0.0 0.0 4.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 91.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 SLC22A8 OAT3 ENSG00000149452 "Solute carrier family 22 member 8" Q8TCC7 11 62989154-63015841 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Detoxification, Ion transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 61 "choroid plexus: 111.4;kidney: 335.0" "Cell type enriched" "Detected in some" 38 "Proximal tubular cells: 347.6" "Cancer enhanced" "Detected in single" "renal cancer: 0.6" "Region enhanced" "Detected in some" "hippocampal formation: 3.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044174 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA044174: AB_10963058" "unprognostic (5.35e-4)" "unprognostic (4.66e-1)" "unprognostic (6.88e-3)" "unprognostic (1.72e-1)" "unprognostic (2.20e-1)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.7 0.0 111.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 335.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.7 3.6 0.0 0.1 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 1.2 0.0 0.0 5.5 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 347.6 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 SLC23A1 "SLC23A2, SVCT1, YSPL3" ENSG00000170482 "Solute carrier family 23 member 1" Q9UHI7 5 139367196-139384553 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "fallopian tube: 54.2;intestine: 65.3;kidney: 40.2;liver: 22.5" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 65.2;Hepatocytes: 19.3;Proximal enterocytes: 131.7;Proximal tubular cells: 27.0" "Group enriched" "Detected in many" 5 "endometrial cancer: 2.1;liver cancer: 7.7;prostate cancer: 4.0;renal cancer: 3.9" "Region enhanced" "Detected in some" "midbrain: 3.2" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "CACO-2: 9.4;HDLM-2: 8.3;Hep G2: 13.6;JURKAT: 15.5;Karpas-707: 10.9;RPMI-8226: 10.9;U-266/70: 16.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA047612 Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" "HPA047612: AB_2680102" "unprognostic (4.00e-3)" "unprognostic (2.66e-3)" "unprognostic (2.63e-2)" "unprognostic (1.75e-3)" "unprognostic (1.93e-1)" "unprognostic (6.36e-6)" "unprognostic (7.41e-2)" "unprognostic (6.55e-2)" "unprognostic (5.88e-2)" "unprognostic (3.90e-2)" "unprognostic (1.01e-1)" "unprognostic (3.77e-2)" "unprognostic (1.22e-1)" "unprognostic (6.51e-2)" "unprognostic (4.16e-2)" "unprognostic (1.55e-2)" "unprognostic (3.65e-3)" 0.2 0.1 0.1 1.2 0.2 2.8 0.2 1.1 0.2 2.3 0.1 3.3 26.3 0.7 0.0 0.3 54.2 2.4 0.1 0.2 0.4 40.2 22.5 0.9 1.7 1.1 3.2 0.3 1.2 0.3 0.2 0.1 0.8 6.3 1.5 0.6 3.2 0.6 0.4 1.9 65.3 0.2 0.1 1.3 1.5 0.2 0.2 5.5 0.2 0.0 1.2 0.4 0.3 0.6 0.3 2.1 0.4 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 9.4 1.3 5.8 3.0 0.0 0.1 0.3 0.0 0.0 0.1 8.3 0.1 0.2 0.8 13.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 15.5 0.1 10.9 0.0 0.2 5.7 1.0 0.1 0.8 0.1 6.8 0.3 10.9 0.5 0.4 0.3 0.3 0.3 1.9 0.0 0.7 5.0 0.1 0.3 0.3 0.3 0.1 0.0 16.6 2.2 7.6 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 1.3 0.1 0.0 0.1 0.2 1.1 0.2 0.2 0.4 1.1 3.2 0.8 0.1 0.2 0.6 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.0 0.1 0.3 0.3 0.3 1.5 2.0 0.0 4.2 0.4 0.4 1.9 5.9 0.2 0.0 65.2 0.7 0.1 0.0 0.0 1.1 0.2 0.0 0.0 0.0 1.5 0.0 0.1 0.4 19.3 0.1 0.0 1.2 3.6 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 1.4 0.1 3.1 0.0 0.4 0.9 131.7 27.0 13.4 0.7 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.8 0.2 0.0 4.2 0.2 SLC23A3 "FLJ31168, SVCT3, Yspl1" ENSG00000213901 "Solute carrier family 23 member 3" Q6PIS1 2 219161465-219170095 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 8 "intestine: 18.4;kidney: 45.6" "Group enriched" "Detected in many" 5 "Proximal enterocytes: 55.9;Proximal tubular cells: 14.4" "Cancer enriched" "Detected in some" 9 "renal cancer: 5.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTCEpi: 4.9;U-266/70: 3.1" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Not detected" "Not detected" HPA019059 Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Cell Junctions" "HPA019059: AB_1857017" "unprognostic (2.49e-2)" "unprognostic (6.65e-2)" "unprognostic (2.05e-4)" "unprognostic (6.97e-2)" "unprognostic (8.41e-2)" "unprognostic (1.22e-2)" "unprognostic (9.07e-2)" "unprognostic (1.93e-1)" "unprognostic (4.01e-2)" "unprognostic (4.35e-2)" "unprognostic (3.10e-1)" "unprognostic (6.12e-4)" "unprognostic (9.42e-2)" "unprognostic (6.48e-2)" "unprognostic (2.41e-2)" "unprognostic (3.34e-1)" "unprognostic (6.52e-5)" 1.1 0.4 1.0 0.9 1.0 0.1 0.9 1.2 0.9 2.8 1.0 3.8 7.6 1.6 0.5 2.2 1.5 0.5 1.0 1.0 1.0 45.6 4.0 1.3 0.7 1.1 1.0 1.8 1.1 0.8 0.5 1.0 1.0 2.4 1.5 0.2 1.0 0.6 0.2 1.9 18.4 0.7 1.0 1.5 1.2 0.1 1.1 0.3 2.4 0.1 0.8 1.1 2.3 1.0 0.5 0.2 0.1 0.6 2.0 1.1 0.4 1.2 0.3 0.2 0.7 1.1 0.7 0.2 0.4 0.8 0.0 1.7 0.4 0.1 0.3 1.1 0.9 1.1 1.2 0.1 0.4 0.1 0.4 0.4 4.9 0.4 1.5 1.9 0.6 0.6 0.1 0.4 0.3 0.2 0.0 0.5 0.0 0.4 0.1 0.3 0.3 0.4 1.6 1.9 0.2 0.5 0.1 0.0 1.3 0.5 0.5 0.5 1.4 1.1 0.7 1.0 0.4 3.1 0.1 1.5 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 1.2 0.9 1.0 1.0 1.1 1.0 1.0 1.0 1.1 1.0 0.6 0.0 0.5 0.0 1.7 1.5 1.4 0.5 0.6 1.1 0.9 1.1 0.3 1.5 0.3 1.8 0.0 0.3 0.5 3.8 1.9 0.2 0.0 0.2 0.8 1.0 1.8 0.4 0.3 0.0 0.1 0.8 0.0 0.9 0.0 0.5 1.1 1.2 0.2 0.0 0.3 4.0 0.0 0.9 0.8 0.0 1.5 1.0 1.8 1.0 1.1 1.2 0.0 0.0 0.0 0.4 6.0 1.2 0.2 1.5 55.9 14.4 0.1 0.2 0.0 0.8 1.0 0.0 0.2 0.7 1.6 0.4 0.8 0.6 3.9 0.9 SLC25A10 DIC ENSG00000183048 "Solute carrier family 25 member 10" Q9UBX3 17 81712236-81721016 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 183.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 42.3;Late spermatids: 76.9;Proximal enterocytes: 50.9;Proximal tubular cells: 84.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "Hep G2: 158.9;SK-BR-3: 116.6" HPA023048 Supported Supported Nucleoplasm,Mitochondria NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria Nucleoplasm "HPA023048: AB_2301950" "unprognostic (7.17e-2)" "unprognostic (2.38e-2)" "unprognostic (2.36e-2)" "unprognostic (1.36e-1)" "unprognostic (9.50e-2)" "prognostic favorable (2.56e-4)" "unprognostic (5.66e-2)" "unprognostic (2.11e-1)" "unprognostic (1.78e-2)" "prognostic favorable (8.14e-4)" "unprognostic (6.73e-2)" "unprognostic (1.33e-1)" "unprognostic (6.02e-2)" "unprognostic (6.32e-2)" "unprognostic (2.76e-1)" "unprognostic (2.05e-1)" "prognostic favorable (1.31e-4)" 17.8 14.8 5.3 3.0 5.0 9.5 16.8 5.6 6.2 6.5 6.4 26.1 21.4 3.8 2.7 38.8 9.2 5.5 10.4 4.6 5.2 72.9 183.3 4.3 2.5 6.6 5.2 4.8 35.8 17.3 6.3 1.8 5.1 17.2 6.8 0.6 26.0 6.1 5.8 17.3 20.1 0.9 5.8 4.8 24.0 35.0 5.4 3.9 9.6 1.9 2.9 9.1 11.5 6.6 45.3 81.8 7.6 38.1 2.9 2.3 15.3 19.2 6.1 23.2 17.4 49.5 18.4 20.2 14.3 4.5 11.2 28.3 10.8 19.3 4.2 14.9 66.2 16.7 49.0 158.9 3.3 37.5 19.5 1.6 10.0 16.5 3.2 4.5 13.6 27.9 28.0 24.3 8.2 85.4 54.3 40.0 7.8 18.8 63.9 41.0 16.3 63.6 21.1 39.6 49.8 34.0 18.1 116.6 4.0 2.0 50.3 20.4 6.1 17.9 58.6 26.5 34.4 15.3 8.3 12.0 7.8 39.0 15.9 0.0 0.2 0.0 0.1 0.3 0.3 0.0 0.1 0.4 0.1 0.2 0.1 0.0 0.0 1.0 0.0 0.1 0.2 0.2 5.3 5.0 5.6 6.2 4.6 5.2 6.6 5.2 5.1 5.8 5.4 6.6 1.4 0.0 2.2 1.6 1.3 0.0 4.5 0.0 2.2 4.9 14.6 7.5 3.8 17.2 3.1 14.7 0.0 16.4 2.3 10.2 25.4 16.9 30.5 22.3 3.8 1.5 4.9 8.2 1.2 22.9 6.9 2.3 18.8 16.4 0.0 5.1 3.6 42.3 8.0 0.0 1.7 15.3 0.0 2.4 0.0 76.9 2.1 2.0 0.0 0.0 0.8 1.9 3.1 0.5 1.2 9.9 19.3 1.9 4.3 4.7 50.9 84.6 7.3 4.2 0.0 1.3 1.6 27.9 3.1 15.9 0.0 4.2 1.5 5.3 27.2 7.9 SLC25A42 MGC26694 ENSG00000181035 "Solute carrier family 25 member 42" Q86VD7 19 19063994-19113030 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 82.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 67.7;Hepatocytes: 52.1;Proximal tubular cells: 39.6;Rod photoreceptor cells: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 2.7;MAIT T-cell: 1.4;memory B-cell: 3.3;memory CD4 T-cell: 1.5;memory CD8 T-cell: 2.4;naive B-cell: 3.2;naive CD4 T-cell: 1.0;naive CD8 T-cell: 1.4;NK-cell: 1.8;T-reg: 1.7" "Group enriched" "Detected in many" 6 "B-cells: 3.3;NK-cells: 1.8;T-cells: 2.7" "Cell line enhanced" "Detected in many" "K-562: 20.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049449 Approved Supported Mitochondria Yes No "Cluster 43: B-cells - Humoral immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 56: Bipolar cells - Visual perception" Mitochondria "HPA049449: AB_2680772" "unprognostic (2.27e-1)" "prognostic favorable (5.04e-4)" "unprognostic (5.79e-2)" "unprognostic (5.67e-2)" "unprognostic (1.35e-1)" "unprognostic (3.42e-3)" "unprognostic (1.27e-3)" "prognostic favorable (4.11e-4)" "unprognostic (6.89e-2)" "unprognostic (2.73e-1)" "unprognostic (1.37e-3)" "unprognostic (3.04e-2)" "unprognostic (5.29e-3)" "unprognostic (1.76e-1)" "unprognostic (2.39e-2)" "unprognostic (4.17e-2)" "unprognostic (2.03e-2)" 8.5 7.5 17.2 4.3 16.9 8.3 7.9 14.5 18.3 13.1 16.7 8.4 5.1 10.1 3.7 5.2 12.5 3.5 15.8 17.9 16.9 34.1 82.0 6.6 9.0 14.9 15.2 16.9 11.3 6.0 14.4 2.6 14.7 9.9 2.4 8.4 9.2 5.2 46.5 6.7 9.3 4.9 13.9 12.7 8.3 7.0 18.0 8.1 25.6 32.6 7.5 9.6 9.1 13.9 7.3 1.0 1.8 3.2 6.8 5.6 2.8 3.5 5.2 5.3 6.0 1.4 14.3 5.2 8.0 3.3 5.3 1.3 3.7 2.9 3.0 1.3 7.0 1.8 2.0 11.8 5.4 0.8 3.6 5.6 2.0 4.0 2.4 4.3 2.4 16.8 20.9 9.2 2.8 6.6 9.0 8.4 1.0 2.0 7.4 6.8 3.2 10.2 2.1 1.3 2.0 1.5 3.7 0.1 1.6 2.4 6.5 4.1 2.2 3.9 2.2 8.2 3.4 10.7 6.2 4.1 4.1 11.2 2.0 0.0 0.1 0.1 2.7 0.3 1.4 3.3 1.5 2.4 0.2 3.2 1.0 1.4 0.0 1.8 0.3 0.4 1.7 0.9 17.2 16.9 14.5 18.3 17.9 16.9 14.9 15.2 14.7 13.9 18.0 13.9 4.6 0.0 13.1 12.4 14.2 3.2 2.8 3.3 2.8 67.7 5.9 6.6 9.7 5.7 4.1 9.2 18.8 7.7 16.5 3.1 13.7 1.5 1.2 2.5 5.4 4.1 8.4 13.7 18.6 3.1 3.8 5.1 4.1 3.6 3.8 8.3 5.3 52.1 1.8 3.3 25.0 3.8 6.1 0.6 1.9 1.6 5.0 1.4 3.6 6.5 1.3 12.5 32.0 16.1 8.6 2.5 4.6 6.4 16.4 2.4 9.2 39.6 3.0 41.4 6.6 9.6 5.8 10.6 7.6 0.9 2.8 4.7 10.9 8.0 3.1 1.7 SLC26A7 SUT2 ENSG00000147606 "Solute carrier family 26 member 7" Q8TE54 8 91209494-91398155 "Metabolic proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "thyroid gland: 330.3" "Cell type enhanced" "Detected in some" "Collecting duct cells: 23.9;Endometrial ciliated cells: 31.6;Endometrial stromal cells: 23.9;Enteroendocrine cells: 45.2;Glandular and luminal cells: 52.0;Hepatic stellate cells: 24.7" "Group enriched" "Detected in some" 11 "renal cancer: 8.7;thyroid cancer: 32.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 44: Endometrium - Transcription" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (5.84e-2)" "unprognostic (8.04e-3)" "unprognostic (4.15e-3)" "unprognostic (1.51e-1)" "unprognostic (2.39e-3)" "unprognostic (2.94e-3)" "unprognostic (1.24e-1)" "unprognostic (1.43e-1)" "unprognostic (1.41e-2)" "unprognostic (8.26e-2)" "unprognostic (4.82e-2)" "unprognostic (3.31e-2)" "unprognostic (2.07e-1)" "unprognostic (5.19e-3)" "unprognostic (6.83e-3)" 1.5 0.1 0.1 0.0 0.2 0.0 0.3 0.2 0.1 1.4 0.2 0.2 0.1 2.7 0.1 0.0 0.5 0.6 0.7 0.0 0.1 23.8 0.0 0.1 3.7 0.1 0.1 0.1 1.2 0.2 0.3 0.3 0.2 0.1 0.4 0.0 0.4 0.2 0.1 0.2 0.1 0.2 0.1 0.1 6.1 0.5 0.2 0.0 330.3 0.3 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.2 0.4 3.9 0.0 1.5 5.9 0.1 0.3 0.4 0.2 0.0 0.0 1.9 0.6 1.1 0.0 0.3 23.9 0.0 0.0 0.0 0.3 13.7 0.1 11.9 31.6 23.9 1.5 45.2 0.0 0.5 0.2 0.0 1.5 1.5 52.0 0.0 0.1 24.7 0.1 0.1 0.0 0.7 0.7 2.0 0.6 0.3 2.9 3.7 0.2 3.6 0.0 0.0 0.1 0.0 0.0 3.8 1.4 0.2 0.0 0.0 0.3 0.0 0.3 1.9 0.2 0.0 0.0 4.4 0.6 1.1 0.0 0.1 0.0 0.4 0.5 0.3 0.1 SLC26A9 ENSG00000174502 "Solute carrier family 26 member 9" Q7LBE3 1 205913048-205943460 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "salivary gland: 72.4;stomach 1: 33.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 50.1;Cardiomyocytes: 26.2;Gastric mucus-secreting cells: 29.0;Proximal tubular cells: 25.4" "Cancer enhanced" "Detected in many" "pancreatic cancer: 9.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.5;Hep G2: 5.1;OE19: 22.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA051485 Enhanced Approved "Cell Junctions" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 11: Alveolar cells - Smell perception" "Cell Junctions" "HPA051485: AB_2681503" "unprognostic (1.55e-2)" "unprognostic (2.70e-2)" "unprognostic (8.77e-2)" "unprognostic (3.14e-1)" "unprognostic (1.83e-2)" "prognostic favorable (8.55e-5)" "unprognostic (1.26e-1)" "unprognostic (1.68e-1)" "unprognostic (3.49e-1)" "unprognostic (8.07e-2)" "unprognostic (8.85e-2)" "unprognostic (3.41e-1)" "unprognostic (2.43e-1)" "unprognostic (2.19e-1)" "unprognostic (1.05e-1)" "unprognostic (7.45e-3)" "unprognostic (2.01e-1)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 1.3 0.2 0.0 0.0 0.1 0.0 7.7 0.0 0.3 0.3 0.0 0.4 0.0 0.2 0.0 0.3 0.0 0.0 0.0 72.4 0.0 0.0 2.0 0.0 0.0 0.0 0.0 33.9 0.0 0.1 0.0 0.4 0.3 5.3 0.0 0.5 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.3 0.0 0.1 0.1 0.0 3.2 50.1 1.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 26.2 0.0 2.7 1.8 0.0 0.0 0.0 0.0 1.9 4.3 0.5 0.2 0.0 0.3 0.0 0.0 0.1 2.2 0.0 1.7 29.0 0.2 2.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.2 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.5 0.0 0.0 0.0 0.4 0.0 25.4 2.3 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.5 1.5 0.0 0.4 SLC27A2 "ACSVL1, FACVL1, FATP2, hFACVL1, HsT17226, VLACS, VLCS" ENSG00000140284 "Solute carrier family 27 member 2" O14975 15 50182196-50236385 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 157.7;liver: 288.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 265.5;Hepatocytes: 205.7;Proximal enterocytes: 81.0;Proximal tubular cells: 198.9;Respiratory ciliated cells: 70.2" "Cancer enhanced" "Detected in many" "liver cancer: 49.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 30 "basophil: 63.5" "Lineage enriched" "Detected in many" 30 "granulocytes: 63.5" "Cell line enhanced" "Detected in many" "A549: 50.0;HaCaT: 89.3;HL-60: 66.3;OE19: 101.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026089 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA026089: AB_1857060" "unprognostic (3.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (2.10e-2)" "unprognostic (3.06e-1)" "unprognostic (1.10e-1)" "unprognostic (4.06e-3)" "unprognostic (3.33e-1)" "unprognostic (1.89e-1)" "unprognostic (6.38e-3)" "unprognostic (4.83e-2)" "unprognostic (1.82e-1)" "prognostic favorable (7.48e-6)" "unprognostic (5.01e-3)" "unprognostic (4.08e-1)" "unprognostic (1.22e-2)" "prognostic favorable (6.40e-4)" 4.8 16.0 1.7 2.9 2.0 6.5 13.3 1.7 3.2 1.6 9.2 18.2 11.1 0.3 65.9 2.6 10.9 2.3 0.0 2.7 2.4 157.7 288.0 1.7 1.5 0.8 1.1 0.1 7.2 4.1 12.4 17.3 0.8 5.4 16.2 3.4 0.9 1.0 0.0 1.2 21.3 0.8 0.8 0.4 1.8 0.9 2.5 0.5 4.6 0.0 1.7 3.6 1.2 0.7 0.0 50.0 0.0 0.0 0.0 0.0 0.1 0.9 0.4 0.9 1.3 26.2 6.9 0.0 0.6 1.2 0.6 89.3 22.8 0.7 2.3 36.0 27.9 37.5 43.0 23.6 0.5 66.3 25.8 0.0 2.1 0.2 0.1 0.0 0.0 16.9 11.6 0.0 0.0 8.3 1.8 44.5 1.7 101.8 1.8 0.0 0.0 1.8 4.7 45.7 40.4 2.6 8.7 1.1 0.0 1.1 4.7 22.8 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 0.0 21.2 0.0 63.5 0.0 0.9 0.8 0.0 0.7 0.3 0.7 0.8 0.0 0.2 0.1 0.2 0.3 2.0 0.0 0.0 0.9 0.5 1.7 2.0 1.7 3.2 2.7 2.4 0.8 1.1 0.8 0.8 2.5 0.7 0.3 0.0 1.1 0.7 2.2 1.0 1.3 8.7 1.2 1.1 1.1 0.3 0.3 0.0 13.6 9.2 0.0 265.5 1.6 17.2 11.7 0.6 0.7 9.8 0.1 0.8 4.2 8.0 4.9 2.0 7.6 0.9 1.5 0.7 6.3 0.1 3.9 205.7 16.4 1.7 6.6 18.9 10.2 3.2 0.3 0.9 0.3 1.2 0.0 1.0 0.0 0.6 1.0 0.0 0.4 1.4 26.6 0.0 0.8 3.3 81.0 198.9 70.2 1.9 0.0 0.0 1.0 4.4 4.2 5.1 0.3 54.9 4.6 0.2 25.9 4.9 SLC28A1 CNT1 ENSG00000156222 "Solute carrier family 28 member 1" O00337 15 84884654-84945798 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "intestine: 49.1;kidney: 48.2;liver: 111.3" "Group enriched" "Detected in some" 5 "Hepatocytes: 38.6;Hofbauer cells: 54.3;Proximal enterocytes: 86.9;Proximal tubular cells: 93.4" "Group enriched" "Detected in some" 63 "liver cancer: 10.9;renal cancer: 33.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA019551, HPA056247" Enhanced Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Nuclear speckles, Cytosol" "HPA019551: AB_2670187, HPA056247: " "unprognostic (3.81e-2)" "unprognostic (1.60e-1)" "unprognostic (2.22e-1)" "unprognostic (7.49e-2)" "unprognostic (5.08e-2)" "unprognostic (7.08e-2)" "unprognostic (8.68e-3)" "unprognostic (1.82e-1)" "unprognostic (1.98e-1)" "unprognostic (2.18e-2)" "unprognostic (1.63e-1)" "unprognostic (8.37e-2)" "unprognostic (1.35e-1)" "unprognostic (7.42e-2)" "unprognostic (7.72e-3)" "unprognostic (6.65e-2)" "unprognostic (1.55e-1)" 0.2 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.1 0.3 0.0 0.0 37.9 0.0 0.5 0.1 0.7 0.2 1.0 0.1 0.3 48.2 111.3 0.0 0.2 0.9 0.3 0.0 0.0 0.2 0.2 1.2 0.7 0.0 0.0 0.0 0.1 0.0 1.5 0.0 49.1 0.0 0.4 0.0 0.1 0.1 0.2 0.0 0.0 3.3 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.3 0.9 0.3 0.7 0.4 0.2 0.6 0.2 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.3 2.2 4.3 0.6 7.3 0.0 0.5 0.0 0.0 11.7 3.0 0.0 0.4 0.1 0.1 0.0 0.0 0.5 0.0 0.5 0.4 0.0 0.6 0.0 0.0 0.4 38.6 54.3 0.0 0.5 2.8 0.0 0.6 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.0 0.5 1.1 0.3 2.5 0.0 0.0 0.0 86.9 93.4 1.4 0.0 0.0 2.6 0.2 0.0 0.0 0.0 0.0 0.8 0.4 0.3 1.5 0.1 SLC2A2 GLUT2 ENSG00000163581 "Solute carrier family 2 member 2" P11168 3 170996347-171026743 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 836.1" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 457.6" "Cancer enriched" "Detected in some" 12 "liver cancer: 105.2" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 55 "CACO-2: 7.7;Hep G2: 27.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB010444, HPA028997" Enhanced Supported "Plasma membrane" NA NA "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "CAB010444: AB_641068, HPA028997: AB_2672860" "unprognostic (9.56e-2)" "unprognostic (1.24e-1)" "prognostic favorable (2.63e-5)" "unprognostic (3.10e-1)" "unprognostic (1.02e-1)" "unprognostic (2.95e-2)" "unprognostic (6.31e-2)" 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.2 0.4 0.0 0.2 0.0 66.1 0.0 0.0 0.0 0.0 5.2 0.0 0.3 0.3 30.8 836.1 0.0 0.0 0.5 0.4 0.0 2.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 27.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.2 0.4 0.3 0.3 0.5 0.4 0.8 0.4 0.4 2.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 90.1 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.2 6.7 0.0 0.0 0.1 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 457.6 0.0 0.0 0.1 3.0 0.0 10.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 2.5 0.0 0.0 0.0 105.4 63.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 1.8 0.0 SLC2A5 GLUT5 ENSG00000142583 "Solute carrier family 2 member 5" P22732 1 9035106-9088478 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 97.3;intestine: 109.1;skeletal muscle: 78.8;testis: 76.4" "Cell type enhanced" "Detected in many" "Early spermatids: 64.3;Paneth cells: 55.6;Plasma cells: 35.3;Proximal enterocytes: 189.4;Spermatocytes: 83.2" "Group enriched" "Detected in many" 6 "glioma: 11.0;renal cancer: 11.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "naive B-cell: 23.3" "Lineage enriched" "Detected in many" 5 "B-cells: 23.3" "Group enriched" "Detected in some" 5 "Daudi: 190.3;THP-1: 47.8;U-266/70: 154.0;U-698: 178.2;U-937: 68.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA005449, HPA075145" Enhanced Enhanced "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA005449: AB_1078985, HPA075145: " "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (8.00e-3)" "unprognostic (2.25e-2)" "unprognostic (6.13e-2)" "unprognostic (2.61e-1)" "unprognostic (1.47e-2)" "unprognostic (5.35e-2)" "unprognostic (4.18e-1)" "unprognostic (6.85e-2)" "unprognostic (3.77e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (5.44e-5)" "unprognostic (8.56e-2)" "unprognostic (2.07e-1)" "unprognostic (8.19e-3)" "unprognostic (8.61e-2)" 7.7 3.4 9.2 5.4 9.2 97.3 5.1 10.5 11.8 2.6 10.1 4.8 109.1 1.3 10.5 3.9 2.6 1.1 2.3 10.3 12.0 38.4 0.6 1.2 20.4 24.1 14.5 2.8 0.6 1.5 2.9 4.9 20.4 15.1 3.6 2.7 2.4 5.1 78.8 6.9 85.3 4.4 14.3 5.6 0.9 76.4 16.1 1.7 0.8 65.9 18.3 3.0 4.2 19.6 0.3 0.1 0.0 0.2 0.2 1.2 0.5 0.2 0.7 0.0 0.6 1.3 0.0 190.3 0.2 0.4 0.1 0.4 1.7 0.1 0.4 25.1 0.2 0.2 3.4 0.0 0.3 3.0 1.6 2.7 2.6 0.6 0.0 2.9 0.0 0.1 0.3 2.0 0.0 0.0 0.1 10.0 0.2 0.0 0.2 4.9 0.0 5.9 0.2 2.0 0.6 0.3 0.3 0.5 0.7 0.1 0.3 47.8 0.2 3.0 0.9 0.5 0.2 154.0 0.2 178.2 0.2 68.2 0.2 4.8 2.5 0.2 0.2 0.5 0.2 4.3 0.2 0.2 0.9 23.3 0.2 0.2 1.4 0.3 0.1 0.2 0.1 1.2 9.2 9.2 10.5 11.8 10.3 12.0 24.1 14.5 20.4 14.3 16.1 19.6 0.3 0.0 0.0 2.0 5.2 2.0 2.0 0.2 10.2 0.0 0.1 0.4 1.9 0.0 0.0 1.8 0.0 0.1 0.0 1.4 7.9 0.3 64.3 0.1 0.3 4.9 1.2 0.0 1.0 0.0 1.1 0.8 0.0 0.4 1.3 0.1 0.4 0.1 4.3 0.0 1.2 7.6 0.0 0.8 1.2 19.3 2.8 2.7 0.0 31.9 0.6 0.6 0.0 2.5 0.9 0.6 55.6 0.4 35.3 2.1 189.4 24.2 0.0 0.1 6.6 2.1 0.4 83.2 8.2 2.7 0.6 0.5 0.3 0.3 8.0 0.2 SLC2A9 "Glut9, GLUTX, URATv1" ENSG00000109667 "Solute carrier family 2 member 9" Q9NRM0 4 9771153-10054936 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 29.3;liver: 21.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 27.4;Proximal tubular cells: 72.6" "Cancer enhanced" "Detected in many" "renal cancer: 6.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 36.9;myeloid DC: 30.5" "Group enriched" "Detected in many" 30 "dendritic cells: 30.5;monocytes: 36.9" "Cell line enhanced" "Detected in some" "HBEC3-KT: 48.1;Hep G2: 23.6;hTCEpi: 19.9;THP-1: 20.5;U-937: 13.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA066229, HPA075669" Enhanced NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA066229: AB_2685639, HPA075669: " "unprognostic (3.21e-1)" "unprognostic (8.99e-3)" "unprognostic (1.25e-2)" "unprognostic (2.01e-1)" "unprognostic (2.14e-2)" "unprognostic (2.56e-2)" "unprognostic (8.94e-2)" "unprognostic (6.94e-2)" "unprognostic (2.86e-2)" "unprognostic (1.28e-2)" "unprognostic (3.16e-1)" "unprognostic (2.23e-1)" "prognostic favorable (1.32e-11)" "unprognostic (1.01e-1)" "unprognostic (3.88e-2)" "unprognostic (3.17e-3)" "unprognostic (1.20e-1)" 1.6 2.6 1.0 2.0 1.2 2.1 4.2 1.3 1.2 2.5 2.7 1.8 10.7 1.4 2.4 5.2 3.5 2.4 2.3 1.1 1.6 29.3 21.4 4.2 2.0 2.3 1.5 1.6 1.0 2.4 1.4 7.6 2.0 3.5 1.6 1.2 16.6 18.8 0.5 2.2 8.4 2.0 1.8 1.8 1.0 0.7 2.0 4.2 2.7 0.5 1.4 6.4 4.0 3.0 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.3 0.1 0.0 0.3 2.4 0.0 3.5 0.7 0.0 7.3 0.0 48.1 0.0 8.2 0.3 0.0 0.0 23.6 1.6 0.1 6.3 3.4 19.9 0.0 4.8 0.0 0.1 0.8 0.0 0.1 0.1 0.0 0.3 2.4 0.0 0.4 0.1 1.5 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 20.5 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.5 0.1 0.0 36.9 0.9 0.3 7.6 0.3 0.3 0.3 0.1 30.5 0.1 0.2 0.1 1.1 0.2 0.9 12.2 0.2 9.1 1.0 1.2 1.3 1.2 1.1 1.6 2.3 1.5 2.0 1.8 2.0 3.0 1.4 0.0 0.0 8.1 1.3 0.9 13.4 27.4 6.2 0.0 4.6 6.1 2.4 0.0 5.7 3.7 2.1 18.7 0.5 1.7 3.9 0.5 5.1 4.1 2.1 1.5 0.0 1.3 4.4 1.1 1.8 1.6 1.1 11.5 1.3 0.5 2.2 5.2 10.3 0.0 5.6 0.9 10.2 8.7 3.7 3.4 0.0 8.8 0.0 15.9 4.4 1.2 1.0 10.6 1.1 0.6 0.5 0.4 0.3 2.0 8.1 72.6 3.0 0.4 0.0 4.6 1.6 1.1 1.9 5.4 0.6 8.5 0.9 0.7 2.5 7.7 SLC30A2 ZNT2 ENSG00000158014 "Solute carrier family 30 member 2" Q9BRI3 1 26037252-26046118 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "pancreas: 99.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 31.0;Endometrial ciliated cells: 30.5;Glandular and luminal cells: 93.7;Proximal tubular cells: 36.2;Syncytiotrophoblasts: 85.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 19.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BEWO: 2.1;RPTEC TERT1: 4.5;WM-115: 3.5" "Region enriched" "Detected in single" 5 "olfactory bulb: 1.2" "Not detected" "Not detected" HPA017979 Approved Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Vesicles "HPA017979: AB_1857085" "unprognostic (4.87e-2)" "unprognostic (6.70e-2)" "unprognostic (3.79e-2)" "unprognostic (1.79e-3)" "unprognostic (1.11e-1)" "unprognostic (2.37e-2)" "unprognostic (2.25e-2)" "unprognostic (2.59e-1)" "unprognostic (3.67e-2)" "unprognostic (1.02e-1)" "unprognostic (6.99e-2)" "unprognostic (1.10e-1)" "prognostic favorable (2.86e-6)" "unprognostic (9.38e-2)" "unprognostic (3.50e-2)" "unprognostic (1.17e-1)" "unprognostic (3.01e-2)" 0.1 1.2 0.4 0.3 0.5 0.6 1.1 1.9 1.0 0.2 0.3 0.5 0.5 0.5 0.3 0.1 0.4 6.7 6.3 0.4 0.3 20.2 0.1 0.2 0.2 0.2 0.0 0.1 99.8 2.2 0.0 4.5 0.1 0.2 0.1 0.5 1.6 2.3 3.8 1.0 0.8 0.1 0.0 0.3 0.3 0.2 0.6 0.0 19.8 0.7 0.1 0.5 0.0 0.2 0.1 0.1 0.0 0.4 0.1 0.0 2.1 0.1 0.1 0.0 0.0 0.3 0.4 0.1 0.4 0.0 0.1 0.3 0.1 0.2 0.0 0.3 0.1 0.2 0.2 0.0 0.0 0.3 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.7 0.0 0.3 0.2 0.3 0.3 0.2 0.0 0.1 0.3 0.3 4.5 0.1 0.4 0.1 0.3 0.5 0.1 0.7 0.3 0.1 0.2 0.2 0.5 0.2 0.1 0.3 0.2 0.3 0.2 0.2 3.5 0.9 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.6 0.3 0.1 0.2 0.1 0.0 0.4 0.5 1.9 1.0 0.4 0.3 0.2 0.0 0.1 0.0 0.6 0.2 0.2 3.2 3.0 0.0 0.6 0.4 0.7 0.0 0.0 4.5 9.1 0.4 13.9 8.6 0.0 9.2 0.0 31.0 0.1 0.5 5.9 11.5 0.0 30.5 9.7 1.0 0.0 0.0 0.0 21.1 2.8 0.5 0.0 93.7 4.5 0.1 0.0 0.0 3.6 0.0 0.0 0.4 0.0 0.0 0.8 0.0 0.3 0.9 3.6 0.0 1.0 0.7 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.6 3.9 36.2 0.0 2.3 6.6 2.1 1.0 0.2 0.4 0.0 0.9 85.1 0.9 0.1 1.1 0.7 SLC34A1 "NAPI-3, NPT2, NPTIIa, SLC11, SLC17A2" ENSG00000131183 "Solute carrier family 34 member 1" Q06495 5 177379235-177398848 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "kidney: 155.4" "Cell type enriched" "Detected in some" 14 "Proximal tubular cells: 143.2" "Cancer enriched" "Detected in single" 12 "renal cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "HEL: 2.4;U-937: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051255, HPA077175" Approved Approved "Nucleoplasm,Nuclear speckles,Plasma membrane,Mitotic spindle,Cytosol" Yes NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 36: HEL - Hemostasis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles, Plasma membrane" "Nucleoplasm, Mitotic spindle, Cytosol" "HPA051255: AB_2681409, HPA077175: " "unprognostic (1.17e-1)" "unprognostic (3.33e-3)" "unprognostic (1.49e-1)" "unprognostic (3.49e-2)" "unprognostic (1.56e-3)" "unprognostic (2.28e-1)" "unprognostic (4.50e-2)" "unprognostic (4.43e-3)" "unprognostic (1.91e-1)" "unprognostic (1.14e-1)" "unprognostic (5.95e-2)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (2.01e-1)" "unprognostic (1.28e-2)" "unprognostic (4.66e-2)" 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 155.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 7.3 0.0 0.0 0.2 0.0 9.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 143.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.0 0.0 0.1 SLC34A3 "FLJ38680, NPTIIc" ENSG00000198569 "Solute carrier family 34 member 3" Q8N130 9 137230757-137236555 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 9.7;kidney: 13.6" "Group enriched" "Detected in some" 9 "Proximal enterocytes: 83.7;Proximal tubular cells: 40.3" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 4.0;HDLM-2: 2.8;HeLa: 3.3;MCF7: 7.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA023776 Enhanced NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA023776: AB_1857102" "unprognostic (2.69e-1)" "unprognostic (4.16e-1)" "unprognostic (9.08e-3)" "unprognostic (1.83e-2)" "unprognostic (2.41e-1)" "unprognostic (1.29e-3)" "unprognostic (4.02e-3)" "unprognostic (1.75e-2)" "unprognostic (1.05e-2)" "unprognostic (9.84e-3)" "unprognostic (2.05e-2)" "unprognostic (2.20e-2)" "unprognostic (5.94e-2)" "unprognostic (1.94e-2)" "unprognostic (9.12e-2)" "unprognostic (5.80e-2)" "unprognostic (2.20e-1)" 0.0 0.1 0.1 0.1 0.3 0.3 0.0 0.0 0.5 0.2 0.0 0.1 0.5 0.2 0.0 2.9 0.4 0.5 0.2 0.2 0.2 13.6 0.0 0.3 0.2 1.8 2.0 0.0 0.6 0.0 1.2 0.0 0.5 0.3 0.0 0.2 1.6 0.0 0.1 0.4 9.7 0.0 0.5 0.2 0.4 0.4 0.8 0.0 0.3 0.0 0.0 0.1 0.5 1.1 0.6 1.2 0.7 1.5 0.0 0.0 0.3 0.4 0.0 0.1 0.0 0.5 4.0 0.5 0.1 0.0 0.1 1.8 0.0 0.0 0.1 2.8 0.3 0.1 3.3 1.5 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.5 0.0 0.2 0.3 0.6 0.0 7.6 0.0 0.1 0.3 0.7 0.8 0.9 0.5 0.0 0.0 0.6 0.0 1.3 0.4 0.9 0.2 0.6 2.2 0.0 0.3 0.3 0.3 1.5 0.1 0.7 0.3 0.3 0.7 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.5 0.2 0.2 1.8 2.0 0.5 0.5 0.8 1.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.3 0.0 0.0 0.0 83.7 40.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 SLC36A2 "PAT2, TRAMD1, tramdorin" ENSG00000186335 "Solute carrier family 36 member 2" Q495M3 5 151314972-151347590 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 60 "kidney: 67.6;skeletal muscle: 80.2;tongue: 29.8" "Cell type enriched" "Detected in some" 8 "Proximal tubular cells: 53.0" "Cancer enriched" "Detected in single" 9 "renal cancer: 0.5" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA044002, HPA062229" Enhanced NA NA "Cluster 17: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA044002: AB_10964214, HPA062229: AB_2684717" "unprognostic (3.47e-1)" "unprognostic (3.40e-1)" "unprognostic (2.26e-2)" "unprognostic (6.23e-2)" "unprognostic (8.38e-3)" "unprognostic (4.66e-3)" "unprognostic (3.03e-1)" "unprognostic (7.73e-2)" "unprognostic (1.92e-2)" "unprognostic (2.11e-1)" "unprognostic (1.92e-1)" "unprognostic (1.20e-3)" "unprognostic (1.43e-1)" "unprognostic (1.05e-1)" "unprognostic (2.18e-1)" "unprognostic (3.89e-2)" 0.2 0.1 0.2 0.1 0.1 0.3 0.1 0.8 0.6 0.0 0.1 0.0 0.0 0.0 0.5 0.8 0.0 0.0 0.2 0.1 0.0 67.6 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.3 0.0 0.2 0.9 0.0 80.2 0.2 0.0 0.0 0.0 0.1 0.0 0.9 0.1 0.0 0.0 29.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.2 0.3 0.1 0.1 0.1 0.3 0.1 0.1 0.0 0.4 0.2 0.2 1.1 0.4 0.1 0.4 0.1 0.1 0.2 0.1 0.8 0.6 0.1 0.0 0.2 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 5.9 0.0 6.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.2 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.0 0.0 0.0 0.0 1.8 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 SLC39A4 "AEZ, AWMS2, ZIP4" ENSG00000147804 "Solute carrier family 39 member 4" Q6P5W5 8 144409742-144416844 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 88.1" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 406.4;Proximal tubular cells: 230.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "CAPAN-2: 36.4;Hep G2: 97.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.59e-1)" "unprognostic (2.35e-3)" "unprognostic (9.16e-2)" "unprognostic (3.84e-2)" "unprognostic (5.63e-3)" "unprognostic (1.46e-1)" "unprognostic (5.40e-2)" "unprognostic (1.54e-1)" "unprognostic (1.61e-1)" "unprognostic (3.28e-2)" "unprognostic (1.41e-2)" "unprognostic (1.24e-1)" "prognostic favorable (9.04e-4)" "unprognostic (2.78e-2)" "unprognostic (3.97e-1)" "unprognostic (9.04e-3)" "unprognostic (1.87e-1)" 0.1 0.2 0.1 1.4 0.2 0.5 0.3 0.0 0.7 0.7 0.0 33.1 88.1 0.4 0.1 0.2 0.9 0.5 0.0 0.2 0.0 18.4 1.3 3.1 0.1 0.0 0.0 3.3 1.4 0.0 0.2 1.0 0.0 1.3 0.5 0.0 1.2 0.3 0.0 0.5 74.9 0.1 0.0 0.7 2.9 1.3 0.0 0.0 3.9 0.0 0.0 0.6 0.6 0.0 2.3 0.2 0.0 0.1 0.0 0.0 2.5 0.1 0.0 0.0 0.0 2.1 36.4 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 6.4 0.8 1.6 0.6 97.4 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.5 2.2 0.0 1.7 0.0 0.4 0.1 0.5 0.1 0.4 0.0 1.1 0.0 0.4 0.9 1.9 0.2 0.4 0.1 0.4 1.7 0.1 0.0 0.1 0.2 0.0 0.0 0.9 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 19.2 24.8 0.3 21.3 18.7 36.6 46.9 38.7 0.2 45.0 50.3 7.4 20.0 24.1 42.3 0.0 17.0 15.4 112.8 50.9 40.0 1.4 41.8 12.9 10.9 42.6 26.3 1.0 42.9 69.7 16.8 29.6 51.9 37.4 8.5 8.9 27.4 32.1 3.3 0.2 95.0 30.5 18.2 21.0 2.0 8.1 23.5 21.4 0.0 25.9 11.3 23.7 0.0 0.1 75.6 135.0 6.4 31.9 60.8 406.4 230.3 26.9 1.0 6.6 7.5 11.1 2.9 33.1 46.4 30.0 11.2 15.4 23.2 98.2 46.3 SLC39A5 ENSG00000139540 "Solute carrier family 39 member 5" Q6ZMH5 12 56230049-56237846 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 32 "intestine: 237.4;kidney: 110.0;liver: 171.1;pancreas: 306.8" "Cell type enriched" "Detected in some" 4 "Proximal enterocytes: 798.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 30.6;liver cancer: 36.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 53 "CACO-2: 39.9;Hep G2: 58.5" "Region enhanced" "Detected in single" "basal ganglia: 1.1" "Not detected" "Not detected" HPA018423 Approved Nucleoplasm,Vesicles NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" Vesicles Nucleoplasm "HPA018423: AB_1857154" "unprognostic (5.94e-3)" "unprognostic (8.29e-2)" "unprognostic (1.82e-2)" "unprognostic (2.19e-7)" "unprognostic (1.73e-1)" "unprognostic (7.79e-2)" "unprognostic (1.56e-1)" "unprognostic (1.36e-1)" "unprognostic (1.08e-1)" "unprognostic (1.32e-1)" "unprognostic (7.33e-2)" "unprognostic (2.93e-3)" "prognostic favorable (5.05e-4)" "unprognostic (2.75e-1)" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (1.96e-4)" 0.3 0.1 0.2 5.5 0.2 0.1 0.3 0.5 0.4 0.3 0.2 73.7 237.4 0.4 0.0 0.1 0.3 6.5 0.2 0.1 0.1 110.0 171.1 0.2 0.4 0.2 0.1 0.4 306.8 0.0 0.2 0.1 0.1 0.3 45.9 6.4 0.1 0.3 0.1 0.3 219.0 2.6 0.1 0.3 1.4 0.2 0.1 0.0 0.3 0.2 0.0 0.2 0.2 0.1 0.0 0.3 0.1 0.2 0.2 0.3 0.5 0.0 0.0 0.1 0.0 39.9 0.4 0.1 0.1 0.1 0.0 0.2 0.0 0.3 0.0 0.6 0.1 0.2 0.2 58.5 0.2 0.1 0.2 0.2 0.1 0.2 0.0 0.1 0.0 0.1 0.1 0.3 0.0 0.2 0.0 0.8 0.0 0.9 0.1 0.2 0.2 0.3 0.5 0.1 0.3 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.4 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 1.4 0.6 0.1 0.0 0.0 0.9 0.1 0.3 0.2 15.7 0.0 3.7 116.7 0.0 0.0 171.9 19.6 0.3 0.6 0.0 0.1 0.2 25.3 2.7 0.2 20.6 0.0 0.1 0.0 0.0 0.0 0.0 2.2 138.9 0.1 0.0 0.2 112.7 0.0 1.6 1.2 1.4 0.0 1.3 0.0 0.0 0.6 0.6 0.0 0.0 0.1 7.4 192.8 0.0 0.0 0.1 798.4 169.9 0.0 1.8 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.0 0.8 0.0 168.7 0.0 SLC47A1 "FLJ10847, MATE1" ENSG00000142494 "Solute carrier family 47 member 1" Q96FL8 17 19495385-19579034 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 127.3;kidney: 100.3;liver: 103.9" "Cell type enhanced" "Detected in many" "Granulosa cells: 189.2;Hepatocytes: 43.3;Proximal tubular cells: 52.9;Skeletal myocytes: 67.8" "Cancer enhanced" "Detected in many" "renal cancer: 37.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "eosinophil: 12.2;plasmacytoid DC: 6.6" "Group enriched" "Detected in many" 6 "dendritic cells: 6.6;granulocytes: 12.2" "Cell line enhanced" "Detected in many" "A549: 21.3;AN3-CA: 16.7;Hep G2: 41.5;U-266/70: 31.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021987 Enhanced NA NA 18000 "Cluster 49: Eosinophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" "HPA021987: AB_1857185" "unprognostic (1.17e-2)" "unprognostic (1.94e-2)" "unprognostic (1.46e-1)" "prognostic favorable (5.54e-8)" "unprognostic (7.87e-2)" "unprognostic (8.34e-2)" "unprognostic (2.92e-2)" "prognostic favorable (1.88e-5)" "unprognostic (4.84e-2)" "unprognostic (6.89e-2)" "unprognostic (6.75e-2)" "unprognostic (1.60e-1)" "prognostic favorable (1.06e-5)" "unprognostic (1.77e-1)" "unprognostic (1.48e-1)" "unprognostic (2.91e-2)" "unprognostic (9.40e-2)" 1.9 127.3 2.1 0.8 2.6 2.7 1.3 3.5 15.8 29.4 9.3 2.0 1.3 16.2 2.5 1.9 7.4 3.8 5.4 15.7 1.6 100.3 103.9 7.0 1.6 3.0 2.5 7.7 0.3 1.4 16.5 0.4 3.1 6.3 1.0 1.2 2.6 12.3 34.1 25.0 1.3 7.7 2.5 3.7 1.2 14.5 4.3 1.5 6.2 37.7 1.3 1.0 10.6 3.3 0.1 21.3 0.6 16.7 0.5 0.1 0.1 0.6 0.5 2.5 2.3 0.0 0.6 0.2 3.9 3.1 8.3 0.1 7.4 0.6 0.6 0.1 9.8 0.2 10.6 41.5 0.2 0.2 0.5 0.4 3.7 1.9 0.3 2.8 5.9 0.0 0.0 0.0 0.0 3.0 0.1 0.4 2.2 0.3 0.8 0.2 0.2 0.2 0.0 1.3 3.9 3.4 7.0 0.1 1.9 5.6 7.1 1.9 0.0 0.1 0.8 0.3 2.0 31.0 13.1 0.1 0.8 0.1 3.6 0.3 1.4 12.2 0.3 0.9 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.6 0.2 0.0 0.1 6.6 0.0 0.5 2.1 2.6 3.5 15.8 15.7 1.6 3.0 2.5 3.1 2.5 4.3 3.3 0.5 6.4 3.7 0.7 1.3 4.7 2.3 0.4 6.2 0.9 0.1 0.8 4.1 4.3 0.1 1.8 0.0 0.0 1.7 0.0 3.9 0.1 15.5 3.0 1.3 1.2 0.0 0.0 3.5 0.0 0.0 4.4 0.0 9.2 5.7 189.2 0.0 43.3 1.5 0.0 14.4 0.0 0.0 2.9 1.2 4.8 3.7 2.5 1.8 3.7 0.4 1.4 0.0 2.5 0.3 0.0 0.0 1.5 3.9 2.3 0.0 52.9 0.8 0.9 6.6 67.8 3.3 0.6 1.1 1.1 6.7 0.0 1.7 0.3 0.0 1.5 SLC47A2 "FLJ31196, MATE2, MATE2-K" ENSG00000180638 "Solute carrier family 47 member 2" Q86VL8 17 19678288-19718979 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 22.3;choroid plexus: 39.6;kidney: 55.8" "Cell type enriched" "Detected in some" 4 "Proximal tubular cells: 91.3" "Cancer enhanced" "Detected in some" "glioma: 2.6;renal cancer: 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "hTCEpi: 2.1" "Not detected" "Not detected" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (4.52e-3)" "unprognostic (8.28e-3)" "unprognostic (1.54e-1)" "unprognostic (4.99e-2)" "prognostic unfavorable (8.95e-4)" "unprognostic (5.22e-2)" "unprognostic (2.72e-1)" "unprognostic (1.99e-2)" "unprognostic (3.29e-2)" "unprognostic (1.51e-1)" "unprognostic (1.36e-3)" "unprognostic (7.77e-2)" "unprognostic (1.04e-3)" "unprognostic (4.33e-2)" "unprognostic (1.61e-1)" "unprognostic (6.44e-2)" "unprognostic (5.71e-2)" 0.1 0.2 2.5 0.0 2.1 0.0 0.2 2.0 1.5 0.1 39.6 0.0 0.0 0.1 6.7 0.4 10.0 0.0 0.1 3.5 6.4 55.8 0.0 0.0 0.0 11.6 22.3 0.1 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.6 0.4 0.2 1.1 2.3 0.3 0.1 8.4 0.0 0.0 0.0 5.0 0.0 0.2 0.2 0.0 0.0 0.1 4.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.1 2.0 1.5 3.5 6.4 11.6 22.3 11.5 8.4 5.0 4.7 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.7 0.6 0.0 0.0 0.9 0.7 0.0 0.2 5.5 0.0 0.1 0.0 0.2 5.9 0.0 0.6 20.9 0.4 0.1 0.0 0.0 3.3 0.0 0.0 0.5 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 1.6 0.0 2.0 0.0 0.0 0.7 0.3 0.9 0.0 1.9 0.0 1.3 0.0 2.0 1.4 0.1 0.0 0.0 0.0 0.8 1.7 91.3 2.5 0.5 0.0 3.5 0.1 0.6 0.8 1.0 0.3 0.0 0.6 0.0 0.2 0.2 SLC4A4 "hhNMC, HNBC1, NBC1, NBC2, pNBC, SLC4A5" ENSG00000080493 "Solute carrier family 4 member 4" Q9Y6R1 4 71062667-71572087 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 119.5;pancreas: 260.3" "Cell type enhanced" "Detected in many" "Astrocytes: 819.1;Cholangiocytes: 133.0;Distal enterocytes: 282.9;Ductal cells: 129.2;Proximal tubular cells: 211.0" "Group enriched" "Detected in many" 5 "glioma: 23.9;pancreatic cancer: 22.5;prostate cancer: 47.4;renal cancer: 19.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 13.0;fHDF/TERT166: 6.1;HBF TERT88: 5.7;hTERT-RPE1: 6.0;RPTEC TERT1: 15.4;U-138 MG: 7.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022493, HPA035628, HPA035629, HPA079220" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 64: Astrocytes - Nervous system maintenance" "CAB022493: , HPA035628: AB_2674708, HPA035629: AB_2674709, HPA079220: " "unprognostic (3.92e-2)" "unprognostic (1.63e-1)" "prognostic favorable (7.69e-4)" "unprognostic (5.32e-2)" "unprognostic (1.01e-1)" "unprognostic (5.09e-2)" "unprognostic (4.24e-2)" "unprognostic (7.49e-2)" "unprognostic (1.46e-1)" "unprognostic (9.22e-3)" "unprognostic (1.04e-1)" "unprognostic (1.74e-1)" "prognostic favorable (1.18e-4)" "unprognostic (7.00e-2)" "unprognostic (2.92e-1)" "unprognostic (2.05e-3)" "unprognostic (2.04e-1)" 5.1 0.7 30.0 2.2 43.6 0.5 1.0 47.0 32.5 11.5 0.0 41.1 54.3 0.4 0.3 1.2 0.9 29.4 6.2 21.5 37.9 119.5 21.7 6.9 0.2 38.6 28.0 0.8 260.3 17.2 5.8 2.7 24.8 34.7 41.2 5.1 2.5 1.1 2.2 0.1 14.6 1.7 38.2 0.8 18.6 0.5 38.5 3.5 22.0 3.5 0.0 4.5 0.4 33.2 0.0 3.5 1.0 0.0 0.0 0.0 0.1 13.0 1.9 2.2 1.6 0.0 0.1 0.0 0.1 6.1 0.5 0.0 0.2 0.0 5.7 0.0 1.7 0.9 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 6.0 0.0 0.7 0.0 0.5 1.2 0.0 4.8 0.2 0.1 0.2 0.0 0.0 0.0 0.9 15.4 4.1 0.9 0.1 0.0 0.0 0.2 1.3 0.0 0.0 0.0 7.7 0.7 5.5 0.6 0.0 0.0 0.0 5.1 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.1 0.6 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 30.0 43.6 47.0 32.5 21.5 37.9 38.6 28.0 24.8 38.2 38.5 33.2 1.5 3.2 37.1 819.1 2.2 0.0 4.3 3.2 0.6 3.2 0.9 0.3 24.0 133.0 31.1 25.8 0.0 0.3 7.2 282.9 15.6 129.2 11.5 2.8 0.5 1.3 8.5 4.0 51.4 24.2 0.1 4.9 33.1 5.8 1.3 0.6 3.9 35.8 0.2 0.0 93.4 65.6 2.0 0.6 0.2 1.5 0.0 2.3 1.8 34.7 1.0 3.9 1.0 29.1 3.7 16.2 60.8 0.0 1.7 40.8 31.8 211.0 10.4 1.5 6.6 1.0 6.2 0.1 1.0 5.5 0.0 0.3 6.8 2.4 68.1 12.3 SLC4A9 AE4 ENSG00000113073 "Solute carrier family 4 member 9" Q96Q91 5 140360194-140375141 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 24 "kidney: 35.5" "Cell type enhanced" "Detected in some" "Distal tubular cells: 1.9;Excitatory neurons: 2.4;Inhibitory neurons: 2.4;Ionocytes: 2.0;Oligodendrocyte precursor cells: 1.5;Oligodendrocytes: 6.4;Spermatocytes: 1.7;Spermatogonia: 1.9" "Cancer enriched" "Detected in single" 8 "renal cancer: 0.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051307 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" Vesicles "HPA051307: AB_2681434" "unprognostic (1.68e-1)" "unprognostic (4.22e-2)" "unprognostic (2.20e-1)" "unprognostic (1.47e-1)" "unprognostic (1.10e-1)" "unprognostic (2.13e-1)" "unprognostic (1.02e-2)" "unprognostic (3.28e-3)" "unprognostic (2.78e-1)" "unprognostic (2.47e-1)" "unprognostic (4.78e-2)" "unprognostic (1.19e-1)" "unprognostic (4.24e-2)" "unprognostic (2.99e-2)" "unprognostic (3.06e-2)" "unprognostic (5.04e-2)" "unprognostic (1.82e-2)" 0.1 0.0 0.3 0.0 0.7 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.5 35.5 0.0 0.1 0.0 0.9 0.6 0.0 0.1 0.0 0.2 0.0 1.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.6 0.0 0.2 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.4 0.7 0.3 0.5 0.9 0.6 1.0 0.5 0.6 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.4 1.9 0.0 0.0 0.1 0.0 0.1 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 2.0 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.5 6.4 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.3 0.0 1.7 1.9 0.0 0.1 0.0 0.1 0.1 0.1 0.2 SLC51B OSTbeta ENSG00000186198 "Solute carrier family 51 subunit beta" Q86UW2 15 65045387-65053397 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 41.8;intestine: 107.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 354.6;Paneth cells: 145.1;Proximal enterocytes: 721.4" "Cancer enhanced" "Detected in many" "liver cancer: 9.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "CACO-2: 18.5;EFO-21: 11.9;Hep G2: 15.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008398, HPA008533" Enhanced Approved Vesicles,Mitochondria No NA "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" Mitochondria Vesicles "HPA008398: , HPA008533: AB_1854824" "unprognostic (6.18e-2)" "unprognostic (6.75e-3)" "unprognostic (1.66e-1)" "unprognostic (1.31e-2)" "unprognostic (5.88e-2)" "unprognostic (9.49e-2)" "unprognostic (9.77e-3)" "unprognostic (1.81e-2)" "unprognostic (3.35e-2)" "unprognostic (2.76e-1)" "unprognostic (2.24e-1)" "unprognostic (4.34e-2)" "prognostic favorable (8.46e-5)" "unprognostic (5.87e-2)" "unprognostic (2.64e-2)" "unprognostic (1.05e-2)" "unprognostic (1.17e-2)" 0.7 1.1 5.8 3.5 5.5 0.8 0.3 4.0 3.9 41.8 0.0 41.9 86.9 3.0 0.3 2.4 3.6 2.8 2.3 3.8 6.5 19.5 2.2 6.1 0.6 7.3 10.9 1.1 0.3 0.0 0.4 0.6 7.7 2.7 29.4 0.7 1.0 0.6 1.0 0.8 107.1 1.7 6.5 0.8 0.8 9.6 11.8 0.0 0.7 0.0 0.0 1.5 0.9 4.2 0.0 1.5 0.2 0.8 0.0 0.1 0.4 0.0 0.0 0.2 0.0 18.5 0.0 0.1 11.9 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.1 15.7 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.4 0.1 0.4 0.4 0.1 0.4 0.0 0.0 0.9 0.4 0.0 0.6 0.5 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.3 0.0 0.1 0.2 0.2 0.4 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 5.5 4.0 3.9 3.8 6.5 7.3 10.9 7.7 6.5 11.8 4.2 0.0 0.0 1.1 0.3 1.3 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 1.5 0.7 0.0 0.0 0.1 0.0 354.6 13.7 0.0 60.8 10.4 0.2 1.2 1.8 2.7 0.0 0.0 0.0 0.5 0.0 1.9 4.5 0.0 0.4 1.8 0.1 0.0 0.0 23.0 0.0 0.3 0.0 14.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 145.1 0.0 0.0 0.0 721.4 73.3 15.6 0.0 6.6 1.0 0.4 27.9 0.5 0.0 0.0 0.1 0.6 0.1 45.8 0.0 SLC5A10 SGLT5 ENSG00000154025 "Solute carrier family 5 member 10" A0PJK1 17 18950345-19022595 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "kidney: 41.6" "Group enriched" "Detected in some" 5 "Late spermatids: 33.7;Proximal tubular cells: 76.9" "Cancer enriched" "Detected in some" 11 "renal cancer: 6.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "intermediate monocyte: 1.8;non-classical monocyte: 4.8" "Lineage enriched" "Detected in single" 7 "monocytes: 4.8" "Cell line enriched" "Detected in some" 5 "U-937: 5.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA052014 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA052014: AB_2681694" "unprognostic (3.74e-1)" "unprognostic (2.92e-1)" "unprognostic (3.04e-2)" "unprognostic (6.11e-2)" "unprognostic (6.56e-2)" "unprognostic (3.36e-4)" "unprognostic (7.36e-2)" "unprognostic (2.39e-1)" "unprognostic (1.52e-1)" "unprognostic (8.94e-2)" "unprognostic (3.24e-2)" "unprognostic (1.53e-1)" "unprognostic (1.09e-2)" "unprognostic (3.43e-2)" "unprognostic (2.61e-2)" "unprognostic (2.75e-2)" "unprognostic (2.11e-1)" 0.2 0.2 0.1 0.6 0.1 2.3 0.2 0.0 0.0 0.3 0.0 0.2 0.1 0.1 0.0 0.4 0.1 0.1 0.9 0.0 0.0 41.6 0.5 0.4 0.9 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.9 1.4 0.0 0.1 3.5 0.1 0.5 0.1 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 5.3 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 4.8 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.3 1.4 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.2 9.8 0.3 8.8 0.0 0.0 0.1 0.0 0.0 0.6 0.2 0.6 0.0 0.0 0.1 0.0 0.2 1.1 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.0 33.7 0.0 0.5 1.8 0.0 0.1 0.0 0.0 1.0 0.3 0.5 0.0 0.0 0.7 0.1 0.0 76.9 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.3 0.3 0.6 0.0 0.0 0.0 SLC5A11 "KST1, SGLT6, SMIT2" ENSG00000158865 "Solute carrier family 5 member 11" Q8WWX8 16 24845841-24911628 "Metabolic proteins, Predicted membrane proteins, Transporters" "Apoptosis, Ion transport, Sodium transport, Sugar transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 43.9" "Cell type enriched" "Detected in some" 19 "Oligodendrocytes: 677.9" "Cancer enhanced" "Detected in some" "glioma: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Hep G2: 8.3;Karpas-707: 2.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035331 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 70: Brain - Nervous system development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Cytosol "HPA035331: AB_10601489" "unprognostic (2.57e-1)" "unprognostic (7.90e-3)" "unprognostic (1.34e-2)" "unprognostic (2.65e-2)" "unprognostic (2.00e-2)" "unprognostic (1.08e-1)" "unprognostic (1.27e-2)" "unprognostic (9.90e-2)" "unprognostic (8.08e-2)" "unprognostic (2.85e-1)" "unprognostic (2.85e-3)" "unprognostic (6.68e-2)" "unprognostic (1.17e-2)" "unprognostic (1.59e-1)" "unprognostic (1.58e-1)" "unprognostic (8.07e-2)" "unprognostic (1.45e-3)" 0.1 0.1 8.5 0.0 24.2 0.0 0.6 22.0 22.6 0.0 5.0 0.3 3.3 0.0 0.0 0.0 0.1 0.2 0.1 8.6 17.0 3.0 0.8 0.1 0.0 27.2 21.5 0.1 0.3 0.0 0.3 0.0 27.3 0.1 0.0 0.0 0.1 0.0 0.0 0.1 8.1 0.0 14.5 0.2 0.1 0.4 20.7 0.0 0.1 0.2 0.0 0.1 0.1 43.9 0.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 24.2 22.0 22.6 8.6 17.0 27.2 21.5 27.3 14.5 20.7 43.9 0.0 0.0 0.0 2.9 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 2.3 0.0 0.8 0.0 0.0 0.1 0.0 0.1 0.0 0.6 0.1 0.0 2.0 1.5 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.5 677.9 0.0 2.4 0.0 0.1 0.0 35.2 7.2 0.2 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.1 0.0 0.2 0.6 0.0 SLC5A12 "MGC52019, SMCT2" ENSG00000148942 "Solute carrier family 5 member 12" Q1EHB4 11 26667020-26723427 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 47.7;intestine: 30.1;kidney: 171.7" "Group enriched" "Detected in some" 23 "Proximal enterocytes: 286.0;Proximal tubular cells: 181.0" "Cancer enriched" "Detected in single" 26 "renal cancer: 9.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 2.3;NTERA-2: 1.7;SuSa: 3.3;T-47d: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA060904 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" Nucleoplasm "HPA060904: AB_2684385" "unprognostic (3.69e-3)" "unprognostic (6.92e-2)" "unprognostic (1.79e-1)" "unprognostic (2.86e-1)" "unprognostic (2.01e-2)" "unprognostic (9.35e-3)" "unprognostic (4.21e-3)" "unprognostic (4.49e-2)" "unprognostic (2.36e-3)" "unprognostic (1.71e-1)" "unprognostic (2.03e-2)" "unprognostic (3.43e-1)" "unprognostic (2.91e-3)" "unprognostic (1.34e-1)" "unprognostic (8.53e-2)" "unprognostic (1.42e-2)" "unprognostic (9.40e-3)" 0.1 0.1 0.3 0.0 0.5 0.9 0.1 0.9 0.4 0.0 0.3 0.2 4.9 0.1 47.7 0.0 0.1 0.1 4.3 0.3 0.4 171.7 1.7 0.1 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.6 0.2 0.1 0.2 1.0 0.1 0.1 0.1 0.3 30.1 0.0 0.0 0.6 0.3 0.2 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.5 0.2 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.3 0.0 0.0 0.1 0.2 1.7 0.3 0.0 0.0 0.0 0.3 0.0 0.5 0.8 0.1 0.7 0.1 0.0 3.3 1.2 0.2 0.2 0.2 0.1 0.2 0.1 1.0 0.3 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.5 0.9 0.4 0.3 0.4 0.2 0.1 0.2 0.0 0.2 0.5 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.1 3.7 0.0 0.1 0.0 2.4 9.8 0.0 1.4 0.2 0.0 0.2 0.0 0.0 0.7 0.0 0.2 0.7 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.3 6.7 0.0 0.0 0.0 0.2 0.0 0.7 0.0 1.0 0.0 0.8 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 286.0 181.0 0.1 0.3 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.6 4.5 3.5 0.1 SLC5A2 SGLT2 ENSG00000140675 "Solute carrier family 5 member 2" P31639 16 31483002-31490860 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sugar transport, Symport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "kidney: 54.2" "Cell type enhanced" "Detected in some" "Early spermatids: 59.7;Late spermatids: 145.7;Proximal tubular cells: 142.9;Spermatocytes: 31.7" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041603 Enhanced NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA041603: AB_10960540" "unprognostic (1.61e-1)" "unprognostic (2.95e-1)" "unprognostic (2.84e-1)" "unprognostic (3.00e-2)" "unprognostic (8.04e-2)" "unprognostic (8.23e-3)" "unprognostic (1.49e-1)" "unprognostic (2.25e-3)" "unprognostic (2.57e-1)" "unprognostic (1.12e-2)" "unprognostic (6.43e-2)" "unprognostic (2.47e-1)" "unprognostic (1.42e-3)" "unprognostic (5.88e-2)" "unprognostic (2.14e-1)" "unprognostic (4.18e-2)" "unprognostic (3.22e-1)" 0.1 0.0 0.1 0.0 0.1 0.0 0.0 1.0 0.3 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 54.2 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 2.9 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.1 1.0 0.3 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.3 0.0 3.7 0.3 0.2 0.3 0.1 0.2 0.0 0.5 0.2 0.4 0.5 1.5 0.1 9.2 0.0 0.2 0.1 0.1 7.9 0.6 59.7 0.6 0.5 0.2 0.0 0.0 0.1 0.5 0.1 0.4 1.5 0.2 0.0 0.1 0.0 0.1 0.2 0.0 0.3 0.5 2.0 0.0 0.5 145.7 2.1 0.9 0.0 0.0 0.0 0.0 0.0 0.5 0.1 1.0 0.1 1.5 0.0 0.1 4.7 142.9 1.7 0.2 0.0 0.1 0.2 31.7 1.1 0.0 0.3 0.1 1.4 0.1 0.6 0.0 SLC5A9 SGLT4 ENSG00000117834 "Solute carrier family 5 member 9" Q2M3M2 1 48222685-48248644 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "intestine: 43.3" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 22.4;Proximal enterocytes: 84.0" "Cancer enhanced" "Detected in many" "liver cancer: 4.1;renal cancer: 3.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "Hep G2: 15.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA050263 Approved "Actin filaments,Cytosol" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Actin filaments" Cytosol "HPA050263: " "unprognostic (3.09e-3)" "unprognostic (1.89e-1)" "unprognostic (6.75e-2)" "unprognostic (5.66e-2)" "unprognostic (2.36e-1)" "unprognostic (1.35e-3)" "unprognostic (3.64e-2)" "unprognostic (4.59e-2)" "unprognostic (3.60e-2)" "unprognostic (1.59e-1)" "unprognostic (7.42e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (4.56e-1)" "unprognostic (2.11e-1)" "unprognostic (4.30e-3)" "unprognostic (1.06e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.8 43.3 0.1 1.2 0.2 0.1 2.5 0.0 0.0 0.0 3.8 7.8 3.0 0.0 0.2 0.2 0.0 3.9 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.8 0.1 1.1 42.0 0.0 0.0 0.0 0.5 0.5 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.2 0.3 0.2 22.4 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.5 2.8 0.0 0.0 0.0 0.0 0.0 3.1 1.9 0.5 6.3 0.5 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.3 0.0 0.5 4.5 0.0 0.7 4.4 0.1 0.0 0.2 2.9 0.0 1.3 0.0 11.0 0.3 0.3 0.0 1.9 0.1 0.0 0.0 7.5 2.9 0.1 1.7 0.4 0.0 0.0 84.0 4.1 0.0 0.0 0.0 0.2 0.1 0.6 0.3 0.0 0.0 0.0 0.1 0.0 3.0 0.0 SLC6A13 GAT2 ENSG00000010379 "Solute carrier family 6 member 13" Q9NSD5 12 220621-262873 "Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 153.1" "Cell type enriched" "Detected in some" 6 "Proximal tubular cells: 324.9" "Cancer enriched" "Detected in some" 18 "renal cancer: 32.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "RPTEC TERT1: 4.6;SuSa: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036449, HPA052726" Supported Nucleoplasm,Nucleoli,Mitochondria,Cytosol NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "Nucleoplasm, Nucleoli, Cytosol" "HPA036449: AB_2675130, HPA052726: AB_2681927" "unprognostic (8.45e-3)" "unprognostic (4.20e-1)" "unprognostic (5.44e-2)" "unprognostic (1.64e-5)" "unprognostic (1.13e-1)" "unprognostic (8.02e-2)" "unprognostic (1.32e-2)" "unprognostic (1.30e-1)" "unprognostic (1.75e-1)" "unprognostic (2.15e-1)" "unprognostic (7.21e-4)" "unprognostic (2.93e-1)" "unprognostic (1.25e-3)" "unprognostic (3.79e-2)" "unprognostic (2.62e-1)" "unprognostic (6.23e-2)" "unprognostic (1.91e-1)" 0.2 0.3 13.4 0.0 16.5 0.1 0.1 11.0 20.1 0.1 13.9 0.1 2.6 0.1 0.3 0.0 7.1 0.0 2.6 12.2 11.9 153.1 36.8 0.8 0.0 11.6 12.6 0.2 0.0 0.0 3.0 0.0 11.7 0.5 0.0 1.1 0.1 0.1 0.5 0.2 0.6 0.0 12.1 0.3 0.1 3.1 13.8 0.1 6.3 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.4 1.6 0.0 0.0 0.1 0.0 0.5 0.0 0.2 0.6 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 16.5 11.0 20.1 12.2 11.9 11.6 12.6 11.7 12.1 13.8 11.7 0.0 0.0 0.6 1.3 1.9 0.0 0.0 0.4 0.0 0.4 0.1 0.1 1.5 0.0 0.1 18.4 2.1 0.0 0.1 0.0 49.0 0.0 1.4 0.6 0.1 0.2 0.0 5.3 3.6 0.0 0.0 0.3 0.0 0.6 0.0 0.0 1.8 27.0 0.0 0.0 1.2 0.0 2.0 1.6 0.0 0.6 0.3 1.7 0.0 17.8 0.0 0.0 0.0 1.5 1.3 0.0 0.0 0.0 0.0 0.1 0.5 324.9 0.7 0.7 0.0 0.4 0.1 0.6 0.4 0.0 0.0 0.3 0.9 0.0 0.0 0.0 SLC6A19 ENSG00000174358 "Solute carrier family 6 member 19" Q695T7 5 1201595-1225111 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 35 "intestine: 142.4;kidney: 88.7" "Cell type enriched" "Detected in some" 5 "Proximal enterocytes: 561.5" "Group enriched" "Detected in many" 4 "renal cancer: 7.9;stomach cancer: 5.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BEWO: 14.3;HEL: 18.3;OE19: 5.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA037415, HPA043207" Enhanced NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 36: HEL - Hemostasis" "Cluster 45: Enterocytes - Digestion" "HPA037415: AB_10672346, HPA043207: AB_2678363" "unprognostic (1.26e-1)" "unprognostic (1.01e-3)" "unprognostic (6.04e-2)" "unprognostic (3.64e-1)" "prognostic favorable (4.14e-6)" "unprognostic (1.37e-1)" "unprognostic (7.36e-2)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 139.7 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 88.7 0.9 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 5.6 0.0 0.0 0.0 0.0 0.0 142.4 0.3 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.4 0.0 5.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 64.3 0.6 1.8 0.0 0.0 0.0 104.4 1.9 0.1 0.1 0.0 0.0 0.1 4.8 2.7 0.0 0.0 14.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 13.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 0.0 0.0 0.0 561.5 76.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.4 0.0 8.7 0.0 SLC6A2 "NAT1, NET, NET1, SLC6A5" ENSG00000103546 "Solute carrier family 6 member 2" P23975 16 55655604-55706192 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 149.4" "Group enriched" "Detected in some" 4 "Early spermatids: 4.3;Extravillous trophoblasts: 10.6;Late spermatids: 4.4;Spermatocytes: 11.5;Syncytiotrophoblasts: 5.6" "Cancer enhanced" "Detected in some" "liver cancer: 1.9" "Region enriched" "Detected in some" 10 "pons: 149.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 29 "SH-SY5Y: 489.1" "Region enriched" "Detected in some" 4 "pons and medulla: 7.8" "Region enriched" "Detected in single" 19 "pons: 13.8" "HPA004057, HPA076311, CAB078195" Enhanced Supported Approved Mitochondria,Cytosol NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol Mitochondria "CAB078195: AB_2665806, HPA004057: AB_1080012, HPA076311: AB_2732307" "unprognostic (9.58e-3)" "unprognostic (5.48e-2)" "unprognostic (1.26e-4)" "unprognostic (4.07e-1)" "unprognostic (4.16e-1)" "unprognostic (8.38e-2)" "unprognostic (2.97e-2)" "unprognostic (3.29e-1)" "unprognostic (2.31e-1)" "unprognostic (3.27e-1)" "unprognostic (2.12e-2)" "unprognostic (2.95e-2)" "unprognostic (1.72e-1)" "unprognostic (6.02e-2)" "unprognostic (8.48e-2)" "unprognostic (1.43e-2)" 0.9 21.7 0.1 0.0 0.1 0.0 0.8 0.0 0.2 2.4 0.0 0.2 0.1 5.4 0.2 0.2 0.5 0.1 0.0 0.1 0.0 0.4 0.4 0.1 0.0 3.8 14.6 0.1 0.0 0.5 0.0 12.6 149.4 0.2 0.3 0.0 1.9 0.6 0.0 13.3 0.2 0.8 0.1 0.0 0.1 6.2 0.0 0.1 0.0 0.0 0.1 0.2 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 5.2 3.7 489.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 3.8 14.6 149.4 0.1 0.0 0.5 1.8 0.0 0.0 0.0 0.0 1.5 0.2 0.4 0.0 0.0 0.3 0.1 0.8 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.3 0.1 0.0 0.3 0.0 0.0 0.0 0.0 10.6 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.5 4.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 11.5 0.3 0.0 0.4 5.6 0.0 0.0 0.0 0.1 SLC7A7 "LPI, y+LAT-1" ENSG00000155465 "Solute carrier family 7 member 7" Q9UM01 14 22773222-22829820 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 131.6;kidney: 300.6" "Group enriched" "Detected in many" 4 "Hofbauer cells: 216.5;Kupffer cells: 410.6;Macrophages: 146.2;monocytes: 164.0;Proximal enterocytes: 423.1;Proximal tubular cells: 327.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 299.9;intermediate monocyte: 410.0;non-classical monocyte: 457.1" "Lineage enriched" "Detected in many" 5 "monocytes: 457.1" "Group enriched" "Detected in many" 4 "BEWO: 217.2;CACO-2: 385.7;OE19: 329.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036227 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036227: AB_10696653" "unprognostic (1.34e-1)" "unprognostic (7.65e-2)" "unprognostic (4.25e-2)" "unprognostic (2.52e-1)" "unprognostic (6.12e-2)" "unprognostic (3.69e-2)" "unprognostic (7.84e-3)" "unprognostic (1.47e-1)" "unprognostic (2.88e-2)" "unprognostic (1.73e-2)" "unprognostic (2.60e-3)" "unprognostic (7.15e-2)" "prognostic unfavorable (6.28e-6)" "unprognostic (2.68e-3)" "unprognostic (1.86e-2)" "unprognostic (2.61e-1)" "unprognostic (1.12e-1)" 15.1 9.0 3.1 37.4 3.2 19.7 6.8 3.8 7.5 7.3 4.3 13.8 107.0 5.3 2.0 3.7 7.8 17.0 5.1 2.8 3.8 300.6 16.4 54.1 29.1 6.9 4.7 2.1 5.2 78.4 1.4 18.2 6.4 3.5 15.0 1.0 5.4 2.8 2.0 3.2 131.6 15.6 5.1 56.8 8.6 32.8 7.1 9.6 4.6 2.8 25.2 14.7 4.1 8.1 0.2 11.2 1.2 0.5 1.9 3.7 217.2 2.2 16.3 0.4 1.4 385.7 34.4 17.0 72.2 1.4 1.2 13.3 0.1 0.0 0.6 0.6 0.2 0.9 0.4 3.7 9.1 1.9 1.6 7.1 1.0 1.0 0.5 1.8 25.3 1.5 0.1 12.8 2.9 0.6 0.4 1.7 3.6 329.0 0.1 2.9 35.5 9.8 0.8 1.3 0.4 0.8 0.6 0.5 2.5 9.4 0.4 8.3 1.3 0.8 1.7 0.6 0.5 2.7 0.9 8.9 0.9 0.8 0.2 0.2 299.9 1.1 0.5 410.0 0.4 19.1 0.2 0.2 99.5 13.8 0.7 0.4 36.5 0.3 457.1 3.4 0.9 155.1 3.1 3.2 3.8 7.5 2.8 3.8 6.9 4.7 6.4 5.1 7.1 8.1 5.3 12.8 7.1 2.0 14.3 1.0 0.2 6.7 1.8 0.2 0.5 1.7 0.9 67.2 5.6 3.7 0.0 1.2 5.7 3.0 11.7 8.2 61.1 1.7 1.2 5.0 1.2 0.0 0.6 6.4 5.2 4.4 2.6 0.4 1.3 0.7 16.1 3.0 216.5 0.0 1.4 7.2 2.0 410.6 16.8 11.8 3.7 146.2 5.4 20.6 164.0 0.4 4.1 0.0 0.8 8.9 12.5 0.0 20.1 0.1 423.1 327.6 9.2 1.3 6.6 0.8 1.4 17.8 2.2 0.4 0.4 1.8 2.7 38.8 6.4 0.1 SLC7A9 CSNU3 ENSG00000021488 "Solute carrier family 7 member 9" P82251 19 32830509-32869767 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Cystinuria, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 124.6;kidney: 68.2" "Cell type enriched" "Detected in some" 7 "Proximal enterocytes: 772.0" "Group enriched" "Detected in some" 7 "liver cancer: 6.6;renal cancer: 5.2;stomach cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "BEWO: 3.4;CACO-2: 8.2;Hep G2: 8.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042591 Enhanced NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "HPA042591: AB_10962500" "unprognostic (4.12e-2)" "unprognostic (5.40e-2)" "unprognostic (6.19e-2)" "unprognostic (3.37e-3)" "unprognostic (1.69e-1)" "unprognostic (1.54e-1)" "unprognostic (4.17e-2)" "unprognostic (3.87e-2)" "unprognostic (1.49e-1)" "unprognostic (1.78e-1)" "unprognostic (1.24e-1)" "unprognostic (2.39e-1)" "unprognostic (9.69e-2)" "unprognostic (5.97e-2)" "unprognostic (3.20e-1)" "unprognostic (4.94e-3)" "unprognostic (5.10e-5)" 0.2 0.1 0.7 0.1 0.7 0.0 0.3 0.7 0.9 0.8 0.6 0.8 78.3 0.4 1.4 0.2 0.5 0.2 0.1 0.7 0.7 68.2 17.3 0.2 0.1 0.7 0.7 0.6 0.3 0.0 0.7 0.1 0.7 1.0 0.2 1.0 0.2 0.2 0.0 0.3 124.6 0.2 0.6 0.3 0.2 0.4 0.7 0.2 0.8 0.0 0.0 0.3 0.5 0.7 0.0 0.1 0.0 0.0 0.1 0.0 3.4 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.7 0.7 0.9 0.7 0.7 0.7 0.7 0.7 0.6 0.7 0.7 0.1 0.0 0.0 2.3 0.5 0.0 0.1 0.0 0.0 1.3 0.2 0.6 0.4 0.0 0.0 5.5 4.2 0.2 0.1 0.0 1.9 0.1 1.6 0.3 0.2 0.1 0.0 0.0 3.1 7.2 8.8 0.2 0.0 0.2 0.0 0.4 0.0 12.2 0.2 0.0 3.0 18.2 0.0 0.0 0.0 0.1 0.6 0.5 0.0 2.8 0.0 0.2 0.0 0.0 1.7 0.6 27.5 0.0 0.0 0.0 772.0 97.8 1.8 1.2 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.5 0.1 11.7 0.0 SLC9A3R1 "EBP50, NHERF, NHERF1" ENSG00000109062 "SLC9A3 regulator 1" O14745 17 74748628-74769353 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Wnt signaling pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 352.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 295.8;Proximal enterocytes: 536.9;Proximal tubular cells: 433.0;Squamous epithelial cells: 303.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 572.4;SK-BR-3: 450.7;T-47d: 873.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001962, HPA009672, HPA027247" Enhanced Approved "Vesicles,Plasma membrane,Centriolar satellite" NA Yes 940000 "Cluster 2: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "Vesicles, Centriolar satellite" "CAB001962: , HPA009672: AB_1857215, HPA027247: AB_10601162" "unprognostic (1.29e-1)" "unprognostic (4.58e-2)" "unprognostic (1.73e-2)" "unprognostic (5.51e-2)" "unprognostic (5.83e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (7.41e-2)" "unprognostic (5.61e-2)" "unprognostic (5.38e-2)" "unprognostic (7.53e-2)" "unprognostic (4.49e-2)" "unprognostic (1.56e-3)" "unprognostic (7.81e-3)" "unprognostic (5.53e-2)" "unprognostic (3.84e-2)" "unprognostic (2.08e-2)" 27.0 146.3 98.9 43.7 103.0 115.7 64.1 105.6 118.1 58.3 127.5 85.1 257.8 22.6 26.0 352.8 89.7 96.6 24.3 98.3 91.0 203.5 269.2 26.5 67.9 100.2 97.6 11.1 85.4 110.3 20.8 33.6 95.6 43.9 59.3 13.0 192.2 71.1 5.2 51.1 274.4 11.6 92.2 61.1 78.2 22.5 102.0 57.7 21.4 10.0 89.2 25.7 103.3 106.1 102.1 82.6 40.4 42.1 23.9 17.5 179.9 24.1 22.4 60.3 58.2 259.6 59.6 22.2 23.9 51.4 32.3 142.2 69.8 46.4 28.3 25.9 66.2 167.4 210.9 350.8 48.6 110.3 108.9 14.4 25.6 48.0 20.6 124.9 50.2 65.8 54.0 115.9 93.8 572.4 262.5 246.7 36.1 286.3 47.6 28.0 45.4 100.6 83.5 71.7 34.6 45.3 25.2 450.7 51.9 110.4 873.8 87.3 17.0 18.7 53.5 43.8 40.2 200.0 98.9 40.9 30.2 145.4 11.2 581.6 91.9 440.8 421.5 133.0 279.8 58.6 255.5 360.4 87.8 52.1 147.5 266.1 318.8 308.8 172.1 90.8 309.0 345.9 98.9 103.0 105.6 118.1 98.3 91.0 100.2 97.6 95.6 92.2 102.0 106.1 12.3 6.4 17.2 29.0 41.8 46.1 21.4 128.7 50.1 2.2 135.3 78.7 17.8 163.0 120.8 31.3 4.2 74.5 122.9 295.8 66.5 194.9 15.8 61.8 7.8 12.0 18.7 24.8 0.4 99.0 56.6 24.7 45.3 85.0 25.3 7.3 7.9 190.6 85.4 5.0 0.5 58.0 105.8 25.7 18.8 9.9 8.7 43.5 28.4 3.7 27.0 86.2 203.9 5.0 11.4 76.5 143.8 41.8 151.1 27.5 536.9 433.0 76.0 5.0 6.6 27.6 20.0 22.5 19.5 303.4 57.4 111.5 126.1 17.1 57.1 34.6 SMIM32 ENSG00000271824 "Small integral membrane protein 32" A0A1B0GUA5 5 136191468-136193162 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 13 "brain: 17.7;intestine: 12.9;kidney: 49.2" "Cell type enriched" "Detected in some" 11 "Proximal tubular cells: 394.0" "Cancer enhanced" "Detected in many" "renal cancer: 12.4" "Group enriched" "Detected in many" 6 "basal ganglia: 17.7;cerebral cortex: 4.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SCLC-21H: 1.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.35e-5)" "unprognostic (3.08e-1)" "unprognostic (7.74e-2)" "unprognostic (7.79e-2)" "unprognostic (2.11e-2)" "unprognostic (9.13e-2)" "prognostic favorable (1.63e-4)" "unprognostic (1.86e-2)" "unprognostic (1.75e-2)" "prognostic favorable (6.13e-4)" "unprognostic (1.51e-1)" "unprognostic (1.19e-2)" "unprognostic (2.78e-1)" "unprognostic (1.14e-1)" "unprognostic (4.85e-3)" "unprognostic (8.05e-2)" 0.0 0.0 1.0 0.2 17.7 0.0 0.0 1.8 4.5 0.0 0.0 4.9 12.9 0.0 0.0 0.0 0.0 2.0 0.0 1.1 1.4 49.2 0.3 0.0 0.0 1.0 1.4 0.0 0.4 0.0 0.0 0.0 0.8 0.4 1.5 0.0 0.1 0.0 0.6 0.0 6.2 0.0 0.8 0.0 1.4 0.3 0.9 0.0 1.2 0.6 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 17.7 1.8 4.5 1.1 1.4 1.0 1.4 0.8 0.8 0.9 1.7 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.4 0.0 0.0 0.0 0.0 33.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 394.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.0 SMLR1 ENSG00000256162 "Small leucine rich protein 1" H3BR10 6 130827406-130837135 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 56.6" "Group enriched" "Detected in some" 11 "Hepatocytes: 243.3;Proximal enterocytes: 144.8" "Cancer enriched" "Detected in some" 20 "liver cancer: 16.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "Hep G2: 81.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA066060 Uncertain NA NA "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA066060: AB_2685607" "unprognostic (1.73e-1)" "unprognostic (7.37e-3)" "unprognostic (1.43e-1)" "unprognostic (1.32e-2)" "unprognostic (2.35e-1)" "unprognostic (1.31e-1)" "unprognostic (1.50e-1)" "unprognostic (6.43e-3)" "unprognostic (2.68e-3)" "unprognostic (3.29e-1)" 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 3.2 56.6 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 81.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.1 10.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 14.7 1.4 243.3 0.1 0.0 0.0 3.1 0.0 5.2 0.0 0.2 0.0 0.1 0.0 2.8 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 144.8 17.5 0.0 1.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 2.0 1.5 0.0 SORD ENSG00000140263 "Sorbitol dehydrogenase" Q00796 15 45023147-45077185 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 163.8;liver: 247.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 138.7;Hepatocytes: 649.4;Prostatic glandular cells: 218.8;Proximal tubular cells: 270.2" "Group enriched" "Detected in all" 4 "liver cancer: 30.3;prostate cancer: 72.5;thyroid cancer: 30.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 10 "basophil: 86.3;eosinophil: 55.9" "Lineage enriched" "Detected in all" 12 "granulocytes: 86.3" "Cell line enhanced" "Detected in many" "SK-BR-3: 57.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040260, HPA040621" Enhanced Approved Cytosol NA NA 2800000 "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA040260: AB_10794872, HPA040621: AB_10795384" "unprognostic (8.18e-2)" "unprognostic (7.58e-2)" "unprognostic (8.19e-2)" "unprognostic (1.51e-1)" "unprognostic (5.69e-3)" "unprognostic (3.90e-2)" "prognostic favorable (6.14e-5)" "unprognostic (3.33e-3)" "unprognostic (1.67e-1)" "unprognostic (4.95e-2)" "unprognostic (7.04e-3)" "unprognostic (1.40e-1)" "unprognostic (4.26e-2)" "unprognostic (1.23e-2)" "unprognostic (8.53e-2)" "unprognostic (2.31e-2)" "unprognostic (1.56e-1)" 2.0 15.7 4.9 3.1 3.8 2.8 53.8 7.4 8.4 163.8 1.9 5.3 7.5 4.3 6.9 10.2 6.7 8.2 5.6 5.0 4.5 50.3 247.0 3.2 2.6 4.3 3.7 2.4 5.7 4.4 3.1 2.5 4.0 87.9 7.8 4.8 5.3 27.0 2.2 16.6 7.2 3.5 4.2 2.3 9.2 12.2 3.9 3.7 89.4 2.8 3.4 9.1 6.9 6.3 12.3 12.2 4.7 20.8 4.4 5.3 5.9 1.8 3.5 12.2 7.0 12.2 5.8 2.7 8.0 5.4 4.1 17.6 19.9 19.1 9.2 29.9 12.3 13.5 12.1 50.3 0.2 18.0 25.5 6.7 18.0 6.6 9.5 5.4 12.5 15.1 11.7 10.6 14.9 8.1 18.4 38.3 39.0 29.4 13.8 0.9 16.6 6.4 16.8 12.1 25.1 12.2 2.1 57.3 5.9 5.2 16.4 22.5 4.7 3.5 38.0 1.6 5.8 8.7 4.5 4.4 14.2 18.6 10.6 86.3 1.7 55.9 1.6 1.5 1.7 5.4 1.3 1.6 1.7 6.9 1.6 1.4 3.8 1.1 2.1 2.4 2.5 2.0 4.9 3.8 7.4 8.4 5.0 4.5 4.3 3.7 4.0 4.2 3.9 6.3 3.9 0.0 3.1 5.5 11.9 7.8 26.5 14.8 17.6 10.8 24.7 17.5 3.2 25.8 28.1 33.1 0.0 1.3 2.3 15.0 29.4 68.2 31.7 40.2 17.4 4.9 84.8 37.5 4.8 138.7 5.1 7.5 31.1 43.7 8.8 11.5 15.7 649.4 16.0 3.3 5.4 32.5 22.4 24.2 6.4 24.1 3.7 12.2 16.0 1.0 13.3 9.0 2.1 7.1 8.9 89.0 18.1 6.0 7.9 218.8 8.0 270.2 42.5 4.7 0.0 8.9 8.9 7.4 2.8 35.1 20.3 1.0 6.5 15.3 39.4 131.2 SOX7 ENSG00000171056 "SRY-box transcription factor 7" Q9BT81 8 10723768-10730511 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "vagina: 42.4" "Cell type enhanced" "Detected in many" "Adipocytes: 115.4;Basal keratinocytes: 61.2;Basal prostatic cells: 67.6;Basal squamous epithelial cells: 148.5;Endothelial cells: 115.1;Squamous epithelial cells: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 11.8;hTCEpi: 21.3;HUVEC TERT2: 25.2;TIME: 6.8" "Low region specificity" "Detected in many" HPA009065 Approved Approved "Nuclear speckles,Golgi apparatus" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" "Golgi apparatus" "HPA009065: AB_1857390" "unprognostic (1.21e-1)" "unprognostic (1.08e-1)" "unprognostic (1.15e-3)" "unprognostic (1.29e-2)" "unprognostic (1.60e-1)" "unprognostic (1.65e-1)" "unprognostic (3.17e-2)" "unprognostic (1.02e-1)" "unprognostic (8.74e-2)" "unprognostic (7.26e-2)" "unprognostic (7.44e-2)" "unprognostic (1.09e-1)" "unprognostic (7.71e-3)" "unprognostic (2.45e-3)" "unprognostic (2.38e-1)" "unprognostic (5.41e-3)" "unprognostic (4.84e-3)" 22.6 3.8 2.5 1.0 2.3 0.1 11.9 1.9 2.6 27.0 1.4 4.2 0.1 4.3 1.1 26.8 4.5 3.6 18.5 2.1 1.8 5.1 4.3 23.2 1.7 2.6 2.2 1.5 2.6 1.0 5.6 17.3 2.5 5.4 1.1 0.4 10.5 2.7 9.8 20.2 3.6 2.3 2.5 2.4 3.7 0.7 2.7 1.5 7.6 6.4 1.9 4.6 42.4 2.0 5.8 0.1 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.4 0.3 0.6 11.8 3.4 4.2 0.1 0.1 0.4 0.1 0.3 0.1 0.0 0.2 0.2 0.1 21.3 0.0 4.3 0.0 25.2 0.0 0.6 0.3 0.0 0.2 0.2 0.2 1.6 0.9 3.2 1.2 0.0 0.0 0.0 2.1 0.6 3.4 2.2 0.0 0.0 1.4 0.0 0.1 6.8 0.1 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.3 1.9 2.6 2.1 1.8 2.6 2.2 2.5 2.5 2.7 2.0 115.4 0.0 11.5 0.3 1.1 61.2 67.6 24.5 148.5 1.2 5.2 4.7 4.8 1.5 6.3 0.0 4.2 4.3 0.1 0.2 0.0 0.2 0.2 14.9 1.9 115.1 0.0 0.0 4.6 0.2 0.8 4.7 0.0 22.9 3.8 0.5 48.5 4.9 0.7 0.0 2.9 0.2 10.2 1.9 8.7 0.1 0.9 0.9 3.6 10.3 0.3 0.5 0.0 1.5 0.8 0.5 0.0 0.4 1.2 17.8 0.1 0.6 3.2 2.2 0.0 8.5 4.4 2.4 1.6 98.9 40.6 12.4 1.8 1.2 0.4 26.6 SPAG5 "DEEPEST, hMAP126, MAP126" ENSG00000076382 "Sperm associated antigen 5" Q96R06 17 28577565-28599025 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.9;kidney: 37.8;testis: 74.0" "Cell type enhanced" "Detected in many" "Early spermatids: 126.0;Erythroid cells: 37.2;Spermatocytes: 72.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 11.7;T-reg: 4.9" "Group enriched" "Detected in many" 6 "granulocytes: 11.7;T-cells: 4.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA022008, HPA022479, HPA024418" Approved Supported "Nuclear bodies,Mitotic spindle,Cytosol" Yes Yes "Cluster 34: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies, Mitotic spindle" Cytosol "HPA022008: AB_1853519, HPA022479: AB_1853521, HPA024418: " "unprognostic (4.71e-2)" "unprognostic (1.32e-1)" "unprognostic (5.31e-3)" "unprognostic (2.32e-3)" "unprognostic (3.50e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (5.43e-5)" "unprognostic (3.37e-3)" "unprognostic (4.84e-3)" "unprognostic (5.97e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (3.49e-2)" "prognostic unfavorable (5.43e-13)" "unprognostic (2.64e-1)" "unprognostic (1.66e-1)" "unprognostic (2.90e-2)" "unprognostic (2.01e-1)" 2.2 3.3 7.8 7.8 7.6 37.9 2.4 5.8 9.1 2.6 3.4 8.3 7.9 1.9 2.4 8.3 1.7 1.8 1.4 7.6 7.7 37.8 14.8 3.4 14.5 6.7 6.8 2.7 1.5 1.1 4.3 5.7 6.7 2.2 10.7 10.8 2.4 0.8 1.0 5.5 9.1 3.4 5.0 7.4 3.6 74.0 7.7 22.4 8.7 0.7 17.3 2.6 3.6 7.5 84.7 87.7 103.3 78.4 5.2 8.6 42.4 65.9 42.4 98.1 78.3 69.2 25.5 59.8 34.2 46.8 91.7 70.2 114.5 42.7 103.8 108.6 72.9 62.9 87.9 80.2 0.6 83.1 76.1 2.9 3.8 78.6 40.4 14.5 52.1 90.6 69.7 101.5 80.7 52.6 109.4 92.9 54.2 68.3 44.5 72.1 144.4 70.9 29.0 43.0 78.6 45.8 96.4 114.9 31.6 84.9 82.2 70.6 25.7 56.4 91.3 46.6 114.6 46.7 72.9 87.3 37.8 60.6 91.8 11.7 0.0 0.0 0.4 0.4 0.7 0.6 1.2 0.9 0.1 1.4 1.1 0.9 0.2 0.8 0.3 0.3 4.9 0.9 7.8 7.6 5.8 9.1 7.6 7.7 6.7 6.8 6.7 5.0 7.7 7.5 0.5 3.2 1.7 0.7 3.3 2.0 0.9 1.3 1.2 5.0 1.1 1.0 0.7 0.0 1.9 0.0 0.0 9.0 1.3 4.7 1.9 0.5 126.0 6.0 1.1 1.5 13.1 37.2 5.2 0.4 12.2 2.6 5.1 1.8 1.3 12.6 3.3 6.3 6.5 3.3 6.0 4.6 4.1 2.7 4.0 25.2 0.9 6.1 0.0 1.9 0.9 0.7 0.0 2.0 1.7 0.4 4.7 0.0 13.1 0.8 8.1 12.5 7.7 3.9 6.6 2.0 2.2 72.6 21.0 5.2 1.0 3.8 2.8 0.9 5.1 1.1 SPOCK2 "KIAA0275, testican-2" ENSG00000107742 "SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2" Q92563 10 72059034-72089032 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 220.1;lymphoid tissue: 114.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 288.4;Bipolar cells: 116.5;dendritic cells: 86.4;Inhibitory neurons: 81.1;Microglial cells: 75.9;NK-cells: 90.6;T-cells: 195.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 117.5;MAIT T-cell: 198.8;memory CD4 T-cell: 115.9;memory CD8 T-cell: 93.5;naive CD4 T-cell: 87.8;naive CD8 T-cell: 89.4;T-reg: 174.3" "Lineage enriched" "Detected in all" 8 "T-cells: 198.8" "Group enriched" "Detected in some" 7 "Hep G2: 50.2;SCLC-21H: 68.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044605 Enhanced "Secreted to blood" NA NA 34000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 24: Non-specific - Transcription regulation" "HPA044605: AB_10965991" "prognostic favorable (4.05e-4)" "unprognostic (3.11e-3)" "unprognostic (2.92e-2)" "unprognostic (2.29e-1)" "unprognostic (2.77e-2)" "prognostic favorable (1.95e-5)" "unprognostic (4.18e-2)" "unprognostic (9.04e-2)" "prognostic favorable (4.72e-4)" "prognostic unfavorable (7.19e-4)" "unprognostic (4.53e-3)" "unprognostic (2.29e-1)" "unprognostic (1.46e-3)" "unprognostic (5.59e-2)" "unprognostic (5.49e-2)" "unprognostic (3.19e-3)" "unprognostic (2.24e-2)" 9.4 46.6 152.6 44.5 108.0 58.1 3.8 160.4 143.2 4.2 2.8 7.6 9.2 4.0 3.1 3.3 6.2 15.3 10.0 117.4 150.1 68.0 2.7 86.5 67.3 212.1 157.7 7.1 1.6 2.0 44.0 3.4 220.1 4.7 5.4 33.4 3.3 5.6 5.1 1.8 32.3 4.4 127.9 29.1 13.6 25.1 207.3 114.4 10.4 6.7 45.3 9.9 3.8 95.6 0.2 0.4 0.3 0.6 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 8.2 0.3 1.4 0.0 0.0 0.9 0.0 0.0 0.0 0.5 0.8 0.2 1.4 50.2 1.6 0.4 1.2 0.1 0.4 0.0 0.0 0.2 0.1 2.7 0.1 0.8 0.0 0.3 0.9 0.3 0.1 0.0 0.2 0.2 0.3 0.1 0.0 0.3 68.2 4.1 0.1 1.5 0.4 0.3 0.0 1.9 0.2 0.0 0.3 0.3 0.1 0.7 1.7 7.3 0.3 0.1 0.2 0.6 0.4 0.2 117.5 1.2 198.8 23.6 115.9 93.5 0.3 18.3 87.8 89.4 13.5 14.4 0.4 3.5 174.3 48.4 152.6 108.0 160.4 143.2 117.4 150.1 212.1 157.7 220.1 127.9 207.3 95.6 17.3 288.4 10.0 51.9 54.6 3.8 0.4 2.1 0.0 116.5 1.9 2.0 3.1 1.5 4.1 14.7 6.2 0.1 86.4 2.4 0.0 3.6 8.1 2.5 1.0 29.9 4.9 3.6 39.6 0.8 0.1 8.4 3.6 1.0 3.8 0.2 7.9 0.4 0.2 3.3 81.1 1.3 2.0 1.6 7.9 10.5 5.3 5.5 5.4 75.9 4.1 5.0 90.6 28.6 8.3 0.0 4.4 6.0 34.2 0.5 0.1 0.5 2.4 17.6 0.0 17.9 2.4 6.3 1.1 0.5 4.4 0.4 195.1 0.8 0.7 0.3 SSTR3 ENSG00000278195 "Somatostatin receptor 3" P32745 22 37204237-37212477 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.6;lymphoid tissue: 11.1;testis: 7.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.3;Late spermatids: 2.0;Microglial cells: 1.9" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 10 "T-cells: 1.1" "Group enriched" "Detected in some" 11 "RPMI-8226: 23.3;SCLC-21H: 8.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022647 Approved NA NA "Cluster 32: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB022647: " "unprognostic (1.63e-2)" "unprognostic (5.58e-3)" "unprognostic (1.32e-2)" "unprognostic (3.18e-2)" "unprognostic (7.03e-2)" "unprognostic (6.26e-5)" "unprognostic (1.11e-1)" "unprognostic (1.72e-2)" "unprognostic (1.90e-2)" "unprognostic (8.95e-2)" "unprognostic (3.88e-3)" "unprognostic (2.93e-1)" "unprognostic (1.51e-7)" "unprognostic (1.55e-1)" "unprognostic (1.24e-2)" "unprognostic (5.61e-3)" "unprognostic (1.06e-2)" 0.1 0.3 2.2 1.0 2.2 0.4 0.0 1.2 6.4 0.0 0.0 0.2 1.3 1.1 0.0 0.0 0.1 0.0 0.0 1.9 2.2 0.1 0.0 0.0 1.8 6.8 3.5 3.3 1.8 0.0 2.6 0.0 6.7 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.5 1.0 1.2 0.6 0.2 7.8 7.6 11.1 0.0 0.0 0.9 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 8.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 1.1 0.9 0.0 0.0 0.0 0.0 0.1 0.2 2.2 2.2 1.2 6.4 1.9 2.2 6.8 3.5 6.7 1.2 7.6 2.3 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.4 0.0 0.0 ST18 "KIAA0535, NZF-3, NZF3, ZC2H2C3, ZC2HC10, ZNF387" ENSG00000147488 "ST18 C2H2C-type zinc finger transcription factor" O60284 8 52110839-52460959 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 82.1" "Cell type enriched" "Detected in some" 39 "Oligodendrocytes: 4055.3" "Cancer enhanced" "Detected in single" "pancreatic cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.7;SCLC-21H: 9.6;U-87 MG: 1.5" "Region enhanced" "Detected in all" "cerebellum: 40.2" "Low region specificity" "Detected in all" HPA044919 Uncertain NA NA "Cluster 70: Brain - Nervous system development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA044919: AB_10959756" "unprognostic (3.66e-1)" "unprognostic (4.34e-2)" "unprognostic (7.47e-2)" "unprognostic (2.04e-2)" "unprognostic (2.78e-1)" "unprognostic (2.42e-2)" "unprognostic (1.22e-1)" "unprognostic (7.11e-2)" "unprognostic (2.12e-1)" "unprognostic (1.58e-1)" "unprognostic (1.55e-3)" "unprognostic (2.82e-1)" "unprognostic (2.53e-5)" "unprognostic (3.29e-1)" "unprognostic (1.35e-1)" "unprognostic (9.34e-2)" "unprognostic (9.84e-3)" 0.0 0.9 18.4 0.1 48.6 0.0 0.0 44.1 24.1 0.0 1.7 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.0 18.0 29.0 0.3 0.1 0.1 0.0 47.8 37.4 0.0 1.9 0.0 4.4 0.1 43.5 0.1 0.3 8.5 0.0 0.0 0.0 0.0 0.5 0.0 22.3 0.0 1.5 0.3 35.7 0.1 0.0 0.0 0.1 0.0 0.0 82.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.4 48.6 44.1 24.1 18.0 29.0 47.8 37.4 43.5 22.3 35.7 82.1 0.0 0.0 0.0 4.9 0.6 0.1 0.1 0.0 0.0 101.5 0.0 0.0 1.1 4.3 0.0 0.0 14.6 0.0 0.0 0.1 0.0 0.0 7.4 0.0 0.0 0.2 49.6 1.3 3.4 0.0 0.4 0.2 5.1 0.0 0.0 0.0 0.0 0.2 1.3 1.7 8.5 0.8 10.2 1.6 11.0 1.7 0.0 3.4 0.0 0.0 0.7 2.4 0.0 13.0 4055.3 0.3 0.0 0.0 0.1 0.3 0.1 0.8 0.0 4.5 0.0 0.0 0.1 0.3 0.3 0.0 0.3 0.1 0.1 0.0 0.3 0.0 ST6GALNAC3 SIAT7C ENSG00000184005 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3" Q8NDV1 1 76074746-76634603 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.0" "Group enriched" "Detected in many" 4 "Microglial cells: 912.5;Oligodendrocytes: 698.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 35.8;HUVEC TERT2: 45.9;SK-MEL-30: 62.3;TIME: 20.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054566, HPA055399" Uncertain Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA054566: AB_2682526, HPA055399: AB_2682806" "unprognostic (7.85e-2)" "unprognostic (1.78e-1)" "unprognostic (2.99e-2)" "unprognostic (2.70e-4)" "unprognostic (2.76e-2)" "unprognostic (2.21e-2)" "unprognostic (6.55e-3)" "unprognostic (7.31e-2)" "unprognostic (2.14e-1)" "unprognostic (4.57e-1)" "unprognostic (1.50e-1)" "unprognostic (5.95e-2)" "unprognostic (9.97e-4)" "unprognostic (3.33e-4)" "unprognostic (5.44e-2)" "unprognostic (1.92e-1)" "unprognostic (3.44e-4)" 8.8 1.4 5.8 1.8 13.3 3.1 6.4 14.3 8.4 1.9 10.4 2.0 0.7 5.9 0.5 1.9 2.7 2.5 4.4 6.9 9.0 8.7 2.0 5.2 2.0 15.2 10.6 2.3 0.9 4.4 2.1 3.1 17.2 1.1 2.4 3.9 1.1 1.6 1.6 0.8 1.4 4.5 13.3 1.4 1.5 0.3 11.3 0.9 13.3 6.5 0.7 2.6 1.6 21.0 0.2 0.0 35.8 0.0 0.6 0.0 0.0 0.0 4.2 0.6 0.4 11.9 0.1 0.6 2.4 0.3 2.3 0.1 0.0 0.4 0.3 0.0 2.5 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.6 0.0 0.0 1.1 45.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 2.9 0.0 1.8 1.7 0.0 0.0 0.0 2.7 8.8 0.0 0.0 62.3 8.3 0.0 0.2 20.6 0.3 2.8 0.1 3.3 0.0 0.0 0.0 0.0 8.4 5.5 0.0 6.3 2.8 0.0 2.2 0.0 2.6 0.3 0.5 2.3 3.8 1.3 1.4 3.9 0.3 4.3 0.0 0.0 1.9 5.8 13.3 14.3 8.4 6.9 9.0 15.2 10.6 17.2 13.3 11.3 21.0 59.8 3.2 1.5 174.3 5.6 0.3 0.2 0.0 0.6 3.2 0.6 1.0 1.2 0.0 0.0 3.7 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.1 4.5 23.2 0.0 0.4 107.0 0.0 0.1 2.5 3.6 0.1 0.0 0.8 66.0 0.8 1.1 0.0 101.4 0.5 0.0 9.8 0.7 0.8 0.0 3.7 5.4 912.5 3.0 12.3 1.0 23.1 698.3 0.2 3.4 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 1.1 1.3 0.2 0.7 0.1 0.4 0.1 2.0 6.9 0.3 0.1 STRA6 FLJ12541 ENSG00000137868 "Signaling receptor and transporter of retinol STRA6" Q9BX79 15 74179466-74212267 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Receptor "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 24.5" "Cell type enhanced" "Detected in many" "Club cells: 17.6;Endometrial stromal cells: 43.1;Extravillous trophoblasts: 12.1;Fibroblasts: 16.1;Proximal tubular cells: 10.3;Syncytiotrophoblasts: 26.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 33.7;CAPAN-2: 94.5;SH-SY5Y: 59.2;WM-115: 142.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040839 Approved NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA040839: AB_10794881" "unprognostic (1.20e-2)" "unprognostic (4.99e-2)" "unprognostic (3.71e-2)" "unprognostic (3.55e-3)" "unprognostic (1.37e-1)" "unprognostic (2.09e-2)" "unprognostic (4.38e-3)" "unprognostic (1.67e-2)" "unprognostic (9.16e-2)" "unprognostic (1.21e-1)" "unprognostic (5.35e-2)" "unprognostic (3.89e-1)" "unprognostic (7.91e-13)" "unprognostic (2.90e-2)" "unprognostic (2.03e-1)" "unprognostic (1.51e-2)" "unprognostic (1.91e-1)" 0.1 1.0 0.1 0.3 0.0 0.0 0.9 0.0 0.4 24.5 0.4 0.1 0.0 4.3 0.5 1.1 3.6 0.3 0.1 0.1 0.1 4.3 0.0 0.2 0.8 0.1 0.0 0.6 0.1 0.0 5.5 7.6 0.0 5.2 0.0 0.0 0.7 1.4 0.0 0.3 0.2 0.2 0.1 0.1 0.0 3.1 0.3 0.2 0.1 0.1 0.5 1.3 2.4 0.0 0.5 33.7 1.9 0.1 0.0 0.0 6.0 1.0 0.2 0.0 0.0 11.7 94.5 0.0 22.1 0.1 0.7 3.4 1.8 0.0 0.0 0.0 0.2 3.0 1.3 2.5 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.4 6.1 0.6 2.9 0.1 0.0 0.4 0.0 0.0 0.0 2.9 17.4 59.2 0.0 3.6 0.0 3.6 0.2 0.1 0.0 0.2 7.3 0.6 1.6 0.1 0.2 0.0 0.6 0.0 142.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.4 1.0 9.7 0.0 0.0 0.2 0.3 1.0 0.0 17.6 0.0 0.0 4.2 0.0 0.0 1.9 0.3 1.7 2.1 43.1 1.3 0.0 0.0 0.1 0.0 12.1 16.1 0.0 1.8 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.0 2.0 0.0 0.8 0.8 6.8 0.4 1.8 1.9 0.1 0.0 0.0 0.0 0.0 4.7 0.0 4.1 0.0 0.4 0.0 10.3 6.6 0.0 0.0 1.3 4.7 0.5 0.5 0.0 0.0 26.4 0.3 0.1 0.0 1.3 STRIP2 "FAM40B, FAR11B, KIAA1170" ENSG00000128578 "Striatin interacting protein 2" Q9ULQ0 7 129434432-129488399 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.0;choroid plexus: 80.0;skeletal muscle: 28.6" "Cell type enhanced" "Detected in many" "Astrocytes: 54.9;Cardiomyocytes: 49.5;Muller glia cells: 62.1;Oligodendrocyte precursor cells: 29.7;Spermatocytes: 79.1;Spermatogonia: 37.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 4 "basal ganglia: 41.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-2197: 44.7" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 102.5" HPA019657 Approved Approved Cytosol NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "HPA019657: AB_1848399" "unprognostic (1.95e-1)" "unprognostic (2.45e-1)" "unprognostic (2.11e-1)" "unprognostic (2.41e-1)" "unprognostic (4.32e-1)" "unprognostic (1.43e-2)" "unprognostic (2.80e-3)" "prognostic unfavorable (6.78e-4)" "unprognostic (9.05e-2)" "unprognostic (2.25e-1)" "unprognostic (8.99e-2)" "unprognostic (1.95e-1)" "unprognostic (2.87e-6)" "prognostic favorable (5.41e-4)" "unprognostic (4.06e-2)" "unprognostic (5.34e-2)" "unprognostic (7.50e-2)" 0.4 2.3 3.7 1.6 41.0 3.6 0.4 3.9 10.2 0.3 80.0 0.6 0.5 0.4 0.3 1.1 0.2 0.8 9.5 4.4 1.8 4.7 0.5 1.0 2.4 0.8 8.0 0.7 0.9 0.1 8.2 0.9 1.0 1.1 0.9 22.1 1.3 0.1 28.6 0.9 0.9 0.5 2.8 1.2 0.7 14.2 8.9 1.3 0.4 19.4 1.7 0.7 0.4 2.4 15.4 6.5 5.9 9.3 2.3 2.0 25.5 6.1 7.7 10.2 9.8 3.6 8.5 6.4 0.8 2.6 33.2 16.9 6.4 5.5 15.4 37.6 5.3 4.9 11.5 3.7 1.5 3.1 25.0 2.4 1.9 17.3 10.6 16.8 17.8 5.7 21.7 3.8 39.7 0.8 8.2 7.8 5.7 3.3 13.4 5.4 10.9 1.2 3.7 5.7 1.3 1.3 14.2 1.0 3.1 4.4 1.8 7.6 6.4 5.9 5.8 44.7 18.0 3.6 2.5 7.6 39.4 7.9 8.5 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 3.7 41.0 3.9 10.2 4.4 1.8 0.8 8.0 1.0 2.8 8.9 2.4 0.4 3.2 1.1 54.9 0.8 0.3 0.3 0.3 0.0 10.5 0.5 0.4 49.5 0.0 0.3 0.0 2.1 0.7 0.8 2.1 0.0 0.9 5.7 0.2 0.9 1.1 0.0 9.1 18.6 3.8 3.8 3.2 2.0 0.4 7.6 1.0 0.4 0.2 0.8 1.7 16.7 1.0 0.0 0.3 0.3 9.9 0.6 2.1 1.8 7.5 7.8 62.1 0.0 29.7 1.0 5.0 4.4 0.7 1.4 0.6 0.1 13.7 0.8 3.5 0.0 2.3 0.9 79.1 37.1 0.5 0.1 0.3 1.3 0.5 0.8 0.6 SUCLG1 ENSG00000163541 "Succinate-CoA ligase GDP/ADP-forming subunit alpha" P53597 2 84423528-84460045 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 554.0" "Cell type enhanced" "Detected in all" "Distal tubular cells: 935.2;Proximal enterocytes: 647.5;Proximal tubular cells: 2949.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036683, HPA036684" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" "Intracellular and membrane" NA NA 350000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "Plasma membrane, Cytosol" "HPA036683: AB_10671708, HPA036684: AB_2675248" "unprognostic (6.84e-3)" "unprognostic (7.16e-3)" "unprognostic (2.58e-3)" "prognostic unfavorable (5.23e-4)" "unprognostic (1.02e-1)" "unprognostic (2.11e-1)" "unprognostic (3.63e-2)" "unprognostic (3.49e-2)" "unprognostic (1.02e-1)" "unprognostic (2.00e-1)" "unprognostic (2.36e-2)" "unprognostic (9.24e-2)" "prognostic favorable (2.21e-8)" "unprognostic (4.94e-2)" "unprognostic (2.08e-1)" "unprognostic (2.81e-2)" "unprognostic (1.23e-1)" 118.7 73.3 70.6 43.1 73.2 48.2 80.0 76.2 92.5 49.9 91.1 156.9 231.1 42.4 78.8 86.9 54.6 41.9 258.1 71.1 74.5 554.0 193.0 41.6 47.8 71.7 70.2 45.7 93.6 244.2 46.8 48.8 72.9 54.3 165.9 38.4 120.6 66.6 274.1 55.4 195.4 63.5 73.8 39.6 81.1 36.9 73.3 61.7 97.6 368.1 63.1 66.4 58.5 76.9 90.2 94.9 73.8 91.1 137.8 91.2 127.7 98.4 85.2 126.0 91.2 224.5 72.0 122.4 67.0 119.8 100.2 126.8 156.7 118.4 149.8 119.3 141.4 105.9 75.4 129.2 116.0 110.6 82.7 109.1 95.6 106.3 143.7 76.7 115.1 97.9 110.1 98.1 117.5 137.4 158.2 101.1 39.4 334.1 170.0 98.3 172.6 134.5 172.2 106.4 89.8 49.3 78.9 163.7 162.3 69.0 99.8 85.4 93.1 96.6 94.6 119.9 124.9 84.2 131.0 107.8 113.9 150.4 88.0 101.6 91.0 80.8 79.0 110.2 88.5 70.2 72.0 88.4 115.4 55.4 79.1 84.3 49.7 102.3 114.3 63.2 107.7 142.7 70.6 73.2 76.2 92.5 71.1 74.5 71.7 70.2 72.9 73.8 73.3 76.9 52.7 64.1 96.5 32.7 61.0 35.4 108.9 129.6 44.3 33.3 105.0 109.1 408.6 131.5 115.2 141.6 22.9 232.3 49.9 218.1 935.2 131.8 49.2 67.1 56.9 57.0 106.3 68.4 45.8 113.2 129.3 69.8 79.5 80.8 91.3 46.0 57.5 210.0 131.7 45.4 43.5 202.1 105.8 71.3 46.0 35.9 54.7 82.2 119.2 16.9 89.8 68.2 58.7 28.1 46.2 67.1 215.4 74.1 57.1 64.2 647.5 2949.2 83.7 36.1 52.6 61.1 98.3 138.9 54.4 111.3 41.3 188.4 64.4 90.7 388.7 111.0 SUGCT "C7orf10, DERP13, FLJ11808, ORF19" ENSG00000175600 "Succinyl-CoA:glutarate-CoA transferase" Q9HAC7 7 40135005-40860763 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 44.4;liver: 28.4" "Cell type enhanced" "Detected in many" "Astrocytes: 76.0;Inhibitory neurons: 38.5;Oligodendrocyte precursor cells: 58.3;Proximal tubular cells: 81.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HBEC3-KT: 43.9;LHCN-M2: 26.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026698, HPA026704, HPA026705" Enhanced NA NA "Cluster 32: T-cells - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA026698: AB_10600191, HPA026704: AB_10600230, HPA026705: AB_10601003" "unprognostic (4.66e-3)" "unprognostic (3.45e-2)" "unprognostic (2.06e-2)" "unprognostic (3.32e-3)" "unprognostic (5.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.14e-3)" "unprognostic (1.75e-2)" "unprognostic (2.61e-1)" "unprognostic (1.80e-1)" "unprognostic (5.27e-3)" "unprognostic (7.65e-2)" "prognostic favorable (3.93e-7)" "unprognostic (2.62e-2)" "unprognostic (3.38e-1)" "unprognostic (3.41e-3)" "prognostic unfavorable (2.53e-4)" 2.4 9.0 1.7 0.9 1.8 0.1 2.3 1.7 2.2 2.2 4.4 4.5 0.7 2.2 1.0 2.1 1.7 2.8 3.9 1.7 2.0 44.4 28.4 0.6 0.8 2.0 2.1 4.1 2.3 4.1 0.9 0.6 1.9 2.0 2.4 2.0 1.4 1.8 10.3 0.9 5.3 2.2 1.8 0.8 1.0 2.8 1.8 0.8 1.8 8.2 1.0 2.0 1.6 1.8 0.8 0.1 4.8 3.4 5.0 11.5 1.8 2.5 4.6 3.2 3.8 2.0 1.0 3.1 1.2 3.5 3.4 0.2 1.4 43.9 5.3 0.0 2.1 2.8 0.3 7.3 6.2 0.4 0.3 14.6 9.7 3.7 2.2 6.9 0.9 1.2 3.9 0.3 26.2 0.0 0.1 0.4 8.1 0.1 3.7 2.9 0.4 0.0 7.4 0.0 0.3 2.7 4.0 1.8 5.8 7.9 0.1 0.7 3.7 14.6 4.2 0.2 1.0 0.3 0.0 0.2 2.8 1.2 3.3 0.0 0.0 0.1 0.2 0.0 0.4 0.5 0.7 0.3 0.0 0.3 1.4 0.9 0.3 0.0 0.0 0.0 0.0 0.2 1.7 1.8 1.7 2.2 1.7 2.0 2.0 2.1 1.9 1.8 1.8 1.8 0.6 3.2 0.5 76.0 1.9 2.0 2.1 26.0 10.2 1.0 1.3 23.0 5.1 1.5 4.4 1.8 8.4 1.5 0.0 10.1 17.6 1.2 31.0 0.9 2.5 0.7 3.6 0.4 19.8 0.8 2.4 3.5 0.0 1.3 0.0 2.2 0.0 21.1 0.3 0.0 38.5 1.5 0.0 1.3 1.0 16.7 6.2 0.7 3.6 14.0 0.1 5.3 0.0 58.3 22.8 0.6 5.6 3.0 0.1 0.8 13.9 81.6 0.8 4.5 6.6 1.4 15.3 2.7 3.1 3.2 0.6 0.8 0.7 7.4 5.3 0.7 SUSD2 "BK65A6.2, FLJ22778, W5C5" ENSG00000099994 "Sushi domain containing 2" Q9UGT4 22 24181487-24189106 "Predicted membrane proteins" Receptor "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 99.8" "Group enriched" "Detected in many" 6 "Alveolar cells type 1: 250.0;Alveolar cells type 2: 151.5;Proximal enterocytes: 154.9" "Cancer enhanced" "Detected in all" "testis cancer: 64.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 29 "SK-BR-3: 898.7" "Low region specificity" "Detected in all" HPA004117 Enhanced Approved "Plasma membrane" NA NA 6800000 "Cluster 19: Lung - Lung function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "HPA004117: AB_1857674" "unprognostic (5.24e-3)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "unprognostic (7.30e-2)" "unprognostic (1.27e-2)" "unprognostic (5.40e-2)" "unprognostic (5.20e-2)" "unprognostic (1.89e-2)" "unprognostic (5.87e-2)" "unprognostic (1.20e-2)" "unprognostic (9.74e-3)" "unprognostic (8.97e-2)" "prognostic unfavorable (3.29e-5)" "unprognostic (2.72e-2)" "unprognostic (2.82e-2)" "unprognostic (1.88e-2)" "unprognostic (3.33e-3)" 12.1 9.6 4.9 1.9 2.8 0.2 9.5 1.7 5.8 13.6 2.2 4.8 12.8 9.8 0.5 2.8 15.0 1.8 12.5 1.6 5.3 32.6 2.9 99.8 2.2 22.9 6.9 5.4 4.3 1.5 7.1 3.6 26.5 5.6 1.0 0.1 4.7 5.6 2.2 28.2 34.6 3.4 6.8 3.6 6.3 3.2 13.2 0.8 17.8 1.4 1.3 5.4 11.0 10.0 5.1 10.4 0.1 0.0 18.8 24.3 0.8 2.4 0.1 0.1 0.0 7.8 0.6 1.4 21.5 0.5 0.4 1.4 0.1 0.5 0.0 0.6 0.3 0.0 0.4 30.6 8.0 0.0 0.3 21.5 0.4 0.1 6.2 0.0 0.1 0.0 0.5 0.3 0.0 9.1 0.3 0.4 0.7 2.5 0.3 0.3 0.0 2.5 0.1 0.2 1.7 13.5 0.7 898.7 0.2 3.6 3.0 0.0 0.0 0.1 0.9 0.7 0.1 1.1 1.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 2.8 1.7 5.8 1.6 5.3 22.9 6.9 26.5 6.8 13.2 10.0 1.7 250.0 151.5 0.3 0.6 0.3 0.3 2.6 0.0 0.0 3.4 3.4 6.8 0.0 20.9 1.8 0.0 13.8 0.3 0.7 5.9 0.1 0.0 1.3 0.7 1.1 1.8 0.0 0.2 0.0 0.7 6.7 0.5 1.3 3.8 0.1 2.9 0.5 1.1 0.0 0.1 5.5 2.0 0.0 0.3 0.4 0.6 0.8 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.4 154.9 27.8 3.6 0.0 0.0 0.6 22.1 1.7 1.3 0.7 2.7 26.4 1.1 0.0 1.6 0.6 SVOP DKFZp761H039 ENSG00000166111 "SV2 related protein" Q8N4V2 12 108907741-109021068 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 14.3;pituitary gland: 7.4;retina: 13.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 41.7;Early spermatids: 65.4;Excitatory neurons: 70.3;Inhibitory neurons: 75.8;Late spermatids: 121.5" "Group enriched" "Detected in some" 9 "glioma: 0.6;pancreatic cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "Karpas-707: 2.8;RPMI-8226: 3.0;SCLC-21H: 1.5;SH-SY5Y: 1.3;U-266/84: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016573 Uncertain NA NA "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA016573: AB_2197027" "unprognostic (6.88e-2)" "unprognostic (1.10e-1)" "unprognostic (2.09e-1)" "unprognostic (6.51e-3)" "unprognostic (2.18e-2)" "unprognostic (3.79e-1)" "unprognostic (1.84e-2)" "unprognostic (1.25e-1)" "unprognostic (3.38e-2)" "unprognostic (4.29e-3)" "unprognostic (3.07e-1)" "unprognostic (4.28e-3)" "unprognostic (3.94e-2)" "unprognostic (2.26e-2)" "unprognostic (6.17e-2)" 0.0 1.5 11.2 0.1 12.4 0.1 0.0 2.2 14.3 0.0 0.0 0.3 0.5 0.0 0.1 0.0 0.0 0.0 1.0 11.3 9.5 0.1 0.2 0.0 0.0 2.9 2.1 0.0 0.7 0.0 7.4 0.0 3.7 0.0 0.1 13.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.0 0.7 0.5 6.4 0.0 0.0 0.1 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 1.5 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 11.2 12.4 2.2 14.3 11.3 9.5 2.9 2.1 3.7 0.4 6.4 6.0 0.2 12.8 9.6 2.6 0.1 0.0 0.7 0.0 0.0 19.7 0.1 0.0 1.3 0.0 5.0 1.8 41.7 1.3 0.0 0.1 0.0 0.1 65.4 0.1 0.1 1.0 16.8 0.0 70.3 0.0 0.3 0.6 0.0 0.2 2.5 0.1 1.1 0.1 0.1 11.8 75.8 0.0 0.0 0.0 0.0 121.5 0.3 1.0 0.0 1.0 0.1 2.1 0.0 4.0 2.8 0.1 0.0 0.7 0.0 0.3 0.0 0.1 0.0 21.9 0.0 1.5 0.7 0.7 0.9 0.0 0.0 0.8 0.5 0.1 0.0 0.4 SYN2 "SYNII, SYNIIa, SYNIIb" ENSG00000157152 "Synapsin II" Q92777 3 12004388-12192032 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Schizophrenia "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "brain: 96.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 338.3;Inhibitory neurons: 543.3;Oligodendrocyte precursor cells: 128.2" "Cancer enhanced" "Detected in many" "glioma: 4.5" "Group enriched" "Detected in many" 5 "amygdala: 67.0;basal ganglia: 77.7;cerebral cortex: 96.8;hippocampal formation: 92.9;white matter: 44.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.3;HMC-1: 4.5;NTERA-2: 3.3;SCLC-21H: 2.7;SH-SY5Y: 11.1;SuSa: 2.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037012, CAB079005" Supported Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "CAB079005: , HPA037012: AB_2675431" "unprognostic (1.62e-3)" "unprognostic (1.60e-2)" "unprognostic (7.54e-2)" "unprognostic (9.87e-3)" "unprognostic (1.73e-1)" "unprognostic (3.19e-1)" "unprognostic (6.32e-3)" "unprognostic (1.08e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (3.68e-2)" "unprognostic (1.24e-1)" "unprognostic (9.77e-2)" "unprognostic (4.89e-4)" "unprognostic (9.94e-2)" "unprognostic (7.35e-2)" "unprognostic (1.78e-2)" 7.0 3.1 67.0 0.4 77.7 0.1 7.1 3.8 96.8 1.4 0.0 2.3 0.4 2.0 1.0 0.3 1.2 0.4 1.0 92.9 2.9 1.5 0.0 1.1 0.0 13.4 0.0 1.5 0.5 4.1 3.4 2.8 10.8 0.5 0.5 7.8 2.4 0.2 0.9 2.5 1.6 1.8 0.0 0.6 1.8 3.6 15.3 0.1 0.2 0.4 0.0 0.3 1.3 44.9 0.0 0.2 0.0 0.0 1.8 0.5 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 2.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.3 0.0 0.2 1.0 0.0 0.2 0.0 0.0 0.0 0.0 3.3 0.1 0.2 0.0 0.0 0.0 0.0 0.2 2.7 11.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 67.0 77.7 3.8 96.8 92.9 2.9 13.4 0.0 10.8 0.0 15.3 44.9 43.4 0.0 0.0 7.8 0.0 0.0 0.4 0.0 0.6 13.9 0.4 2.4 1.4 0.0 0.0 0.0 6.2 1.7 0.1 0.0 0.0 0.0 0.6 0.2 0.1 4.5 0.0 0.0 338.3 0.0 0.4 0.9 0.0 0.3 0.0 0.2 0.7 0.0 0.6 13.5 543.3 0.0 0.0 1.8 0.0 1.8 0.0 0.3 0.0 4.7 0.1 2.5 0.0 128.2 8.3 0.3 0.0 0.0 0.0 0.3 0.0 2.7 0.0 3.7 0.0 0.7 0.7 4.9 6.9 0.0 0.0 0.8 0.1 0.1 0.0 0.2 SYT6 ENSG00000134207 "Synaptotagmin 6" Q5T7P8 1 114089291-114153880 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 13.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.1;Early spermatids: 6.1;Excitatory neurons: 5.9;Late spermatids: 14.1;Microglial cells: 27.2;Oligodendrocyte precursor cells: 7.5" "Cancer enhanced" "Detected in some" "glioma: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "NTERA-2: 22.0;WM-115: 15.2" "Group enriched" "Detected in all" 7 "basal ganglia: 31.2;olfactory bulb: 71.2" "Low region specificity" "Detected in many" HPA058362 Approved Vesicles NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA058362: " "unprognostic (7.12e-2)" "unprognostic (2.03e-2)" "unprognostic (3.26e-3)" "unprognostic (1.04e-1)" "unprognostic (9.37e-2)" "unprognostic (2.49e-1)" "unprognostic (4.11e-2)" "unprognostic (3.60e-3)" "unprognostic (1.19e-1)" "unprognostic (4.71e-1)" "unprognostic (5.50e-2)" "unprognostic (1.01e-1)" "unprognostic (2.82e-1)" "unprognostic (2.11e-3)" "unprognostic (1.48e-1)" "unprognostic (1.48e-2)" "unprognostic (1.18e-1)" 0.0 0.8 2.7 0.2 4.2 0.0 0.7 1.5 2.8 0.0 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.0 3.0 13.5 1.5 0.0 0.0 0.0 4.8 4.5 0.8 3.1 0.1 0.1 0.5 3.9 0.4 0.1 1.4 0.0 0.0 0.1 0.0 0.0 0.0 7.9 0.0 0.0 0.3 9.5 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 22.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.7 2.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 4.2 1.5 2.8 3.0 13.5 4.8 4.5 3.9 7.9 9.5 4.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 7.1 0.1 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 6.1 0.0 0.2 0.3 0.0 0.0 5.9 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.4 0.0 2.4 0.0 0.0 0.0 0.4 14.1 0.0 1.2 3.6 27.2 0.0 0.7 0.0 7.5 0.6 0.0 0.0 0.0 0.0 0.3 0.0 4.3 0.0 0.7 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.1 3.9 0.0 0.0 TACR3 "NK3R, NKR, TAC3R" ENSG00000169836 "Tachykinin receptor 3" P29371 4 103586031-103719985 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.4;retina: 2.7;urinary bladder: 1.9" "Group enriched" "Detected in some" 9 "Bipolar cells: 13.1;Excitatory neurons: 6.7;Extravillous trophoblasts: 4.5;Oligodendrocytes: 10.5;Skeletal myocytes: 11.4" "Not detected" "Not detected" "Region enhanced" "Detected in many" "pons: 8.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 11 "BEWO: 7.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA009418 Uncertain NA NA "Cluster 77: Retina - Visual perception" "Cluster 28: BEWO - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "HPA009418: AB_1857727" "unprognostic (3.81e-2)" "unprognostic (2.92e-1)" "unprognostic (2.29e-1)" "unprognostic (3.50e-1)" "unprognostic (3.21e-1)" "unprognostic (5.52e-1)" "unprognostic (3.80e-1)" "unprognostic (3.42e-2)" "unprognostic (1.72e-2)" 0.0 0.0 2.7 0.0 0.3 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.4 0.2 0.0 0.1 0.0 1.4 1.5 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 2.7 0.0 0.0 0.1 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 1.9 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.3 0.1 0.4 0.3 2.4 1.4 1.5 8.4 1.7 0.9 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 6.7 0.0 4.5 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 1.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 11.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TCN2 "D22S676, D22S750, TC2" ENSG00000185339 "Transcobalamin 2" P20062 22 30607003-30627271 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cobalt transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 115.8" "Cell type enhanced" "Detected in many" "Adipocytes: 105.0;Hepatic stellate cells: 137.4;Kupffer cells: 144.1;Proximal enterocytes: 563.6;Proximal tubular cells: 125.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 43.8;intermediate monocyte: 66.5;non-classical monocyte: 24.4" "Lineage enriched" "Detected in many" 8 "monocytes: 66.5" "Cell line enhanced" "Detected in many" "ASC TERT1: 117.6;HUVEC TERT2: 142.6;Karpas-707: 184.0;RPTEC TERT1: 70.7;TIME: 85.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000837 Approved Cytosol "Secreted to blood" NA NA 19000000 "Cluster 7: Monocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 45: Enterocytes - Digestion" Cytosol "HPA000837: AB_1080235" "unprognostic (6.43e-2)" "prognostic favorable (3.47e-4)" "unprognostic (1.53e-3)" "unprognostic (3.17e-1)" "unprognostic (1.49e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (2.64e-4)" "unprognostic (1.52e-2)" "unprognostic (2.90e-1)" "unprognostic (1.07e-1)" "unprognostic (4.03e-2)" "unprognostic (1.59e-1)" "unprognostic (6.95e-3)" "unprognostic (4.94e-3)" "unprognostic (2.09e-2)" "unprognostic (1.30e-1)" "unprognostic (1.50e-1)" 49.6 30.6 24.6 16.0 24.1 5.5 37.9 25.5 30.6 25.9 27.1 23.4 23.6 28.7 20.3 8.6 21.5 50.1 28.7 22.7 25.3 115.8 17.3 37.7 35.3 27.1 26.1 14.8 12.1 8.6 15.1 18.6 27.7 16.0 27.8 11.1 13.2 45.4 6.0 9.0 59.5 36.8 25.5 46.7 17.4 21.9 29.7 6.4 26.4 13.7 10.0 22.0 14.7 25.3 0.2 9.5 41.8 0.2 24.6 117.6 1.4 3.1 30.9 8.0 13.1 4.6 21.2 0.6 45.7 6.2 0.7 1.5 3.7 2.2 2.5 0.0 2.3 0.2 1.2 2.0 58.5 0.6 33.7 19.8 2.5 6.1 5.1 8.8 142.6 0.0 0.8 184.0 12.7 0.1 0.1 3.3 16.4 11.7 1.0 4.9 6.0 64.2 70.7 1.1 14.4 1.9 0.3 0.6 12.0 2.8 0.4 2.0 85.3 26.4 3.5 3.3 1.3 5.1 1.4 0.2 9.5 1.7 0.6 0.0 43.8 0.0 0.1 66.5 0.7 0.0 0.8 0.4 7.9 0.0 0.3 0.6 1.4 0.0 24.4 1.5 0.2 18.8 24.6 24.1 25.5 30.6 22.7 25.3 27.1 26.1 27.7 25.5 29.7 25.3 105.0 3.2 3.9 3.9 3.7 5.2 2.2 4.7 0.6 8.0 7.1 5.1 6.5 27.1 13.7 12.9 20.9 0.4 0.5 70.9 7.9 7.8 1.1 3.5 5.4 64.6 6.7 0.8 0.2 6.0 0.8 19.5 5.1 6.2 4.5 23.4 137.4 5.6 45.9 1.7 1.9 28.6 4.1 144.1 9.4 1.4 10.5 53.8 23.2 8.4 8.8 7.4 0.0 5.5 1.7 5.1 50.2 9.8 13.5 2.0 563.6 125.8 2.8 29.1 13.1 0.9 5.5 1.0 12.6 0.5 5.3 0.4 2.2 5.6 21.0 2.7 TENM2 "KIAA1127, ODZ2, Ten-M2, TEN2" ENSG00000145934 "Teneurin transmembrane protein 2" Q9NT68 5 167284799-168264157 "Predicted membrane proteins, Transporters" "Cell adhesion, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 9.8;heart muscle: 35.1" "Group enriched" "Detected in many" 5 "Astrocytes: 512.9;Excitatory neurons: 706.2;Inhibitory neurons: 965.9" "Cancer enriched" "Detected in many" 6 "head and neck cancer: 15.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 66.1;HBEC3-KT: 43.0;HDLM-2: 43.3;U-138 MG: 74.6;U-2 OS: 64.0;U-251 MG: 50.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA038018, HPA038420, HPA068691" Uncertain Approved Nucleoli No No 11000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoli "HPA038018: , HPA038420: AB_10674682, HPA068691: AB_2686019" "unprognostic (6.00e-2)" "unprognostic (1.50e-1)" "unprognostic (2.94e-2)" "unprognostic (9.16e-3)" "unprognostic (3.88e-3)" "unprognostic (3.81e-3)" "unprognostic (5.81e-2)" "unprognostic (2.41e-1)" "unprognostic (4.62e-2)" "unprognostic (2.10e-2)" "unprognostic (3.68e-3)" "unprognostic (4.34e-2)" "unprognostic (4.69e-5)" "unprognostic (3.47e-2)" "unprognostic (1.03e-1)" "unprognostic (5.16e-4)" "prognostic unfavorable (7.52e-4)" 0.1 0.5 2.9 0.0 4.7 0.0 1.9 0.0 9.8 1.3 0.0 0.2 0.4 0.0 0.5 1.9 0.1 0.4 35.1 6.0 1.2 0.8 1.3 0.2 0.0 0.6 0.1 0.7 0.1 0.0 0.7 0.0 1.6 2.2 0.1 4.1 0.5 1.0 0.0 3.2 0.2 0.0 0.0 0.0 0.1 1.3 4.3 2.2 0.4 0.5 1.0 0.1 2.0 0.0 0.1 0.0 13.4 0.0 0.0 0.4 0.0 1.9 0.0 0.7 1.8 0.0 0.0 0.0 0.0 66.1 1.7 0.0 0.0 43.0 0.8 43.3 0.0 0.0 0.2 0.0 2.0 0.0 0.0 3.0 7.4 0.3 5.3 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.6 0.0 0.0 0.3 9.8 0.2 0.0 0.0 6.6 0.0 0.1 0.0 0.1 2.4 3.8 0.1 0.0 74.6 64.0 0.1 50.0 0.0 0.0 0.0 7.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 4.7 0.0 9.8 6.0 1.2 0.6 0.1 1.6 0.0 4.3 0.0 0.5 0.0 0.0 512.9 0.0 14.8 1.1 20.3 33.6 15.5 0.3 13.0 144.0 0.0 1.4 0.0 18.8 0.0 0.0 1.0 0.0 3.4 23.5 0.1 0.3 1.7 0.0 0.0 706.2 0.2 0.0 2.2 0.0 0.2 1.3 1.6 0.4 5.1 0.1 121.1 965.9 0.7 0.0 0.0 1.2 18.2 4.4 0.2 1.8 36.5 0.0 2.3 0.0 21.6 12.8 0.0 0.0 61.7 0.0 1.4 0.3 0.0 0.6 1.8 0.0 0.4 1.5 1.2 1.1 1.4 1.7 0.0 0.1 0.0 0.4 0.1 TINAG ENSG00000137251 "Tubulointerstitial nephritis antigen" Q9UJW2 6 54307859-54390142 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "kidney: 110.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 48.6;Distal tubular cells: 23.5;Proximal enterocytes: 72.5;Proximal tubular cells: 207.1" "Cancer enriched" "Detected in some" 4 "renal cancer: 15.8" "Group enriched" "Detected in some" 6 "medulla oblongata: 1.7;pons: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 33 "RPTEC TERT1: 91.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035427, HPA073753" Approved "Secreted to extracellular matrix" NA NA 40000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA035427: AB_10601822, HPA073753: " "unprognostic (7.62e-3)" "unprognostic (1.12e-2)" "prognostic unfavorable (2.05e-5)" "unprognostic (7.27e-2)" "unprognostic (5.99e-3)" "prognostic favorable (8.75e-5)" "unprognostic (7.10e-2)" 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.2 0.0 0.0 14.0 11.7 0.0 0.0 0.0 0.0 1.7 0.1 0.2 0.0 110.4 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 13.8 0.0 0.0 0.0 0.2 0.0 14.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 91.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.0 1.7 0.1 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 7.3 0.0 0.0 0.0 48.6 23.5 0.0 1.0 0.1 0.0 0.0 9.7 0.0 2.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.6 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 15.3 0.0 0.0 0.0 72.5 207.1 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.3 0.0 18.4 0.0 TM6SF2 Lpr4 ENSG00000213996 "Transmembrane 6 superfamily member 2" Q9BZW4 19 19264364-19273391 "Predicted membrane proteins, Transporters" "Lipid metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "intestine: 75.5;liver: 33.7" "Cell type enriched" "Detected in some" 6 "Proximal enterocytes: 231.1" "Cancer enhanced" "Detected in many" "liver cancer: 6.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 1.4;HHSteC: 1.8;LHCN-M2: 1.5;NTERA-2: 1.0;SH-SY5Y: 1.8" "Low region specificity" "Detected in single" HPA066026 Uncertain NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "HPA066026: AB_2685598" "unprognostic (2.41e-1)" "unprognostic (4.81e-3)" "unprognostic (1.49e-1)" "unprognostic (1.15e-3)" "unprognostic (3.29e-1)" "unprognostic (2.35e-1)" "unprognostic (1.39e-3)" "unprognostic (4.00e-2)" "unprognostic (4.15e-2)" "unprognostic (4.53e-4)" "unprognostic (9.55e-3)" "unprognostic (4.37e-2)" "unprognostic (1.38e-1)" "unprognostic (1.61e-1)" "unprognostic (4.56e-2)" "unprognostic (1.51e-1)" "unprognostic (6.15e-2)" 0.2 0.4 0.2 0.1 0.2 0.0 0.2 0.2 0.5 1.0 0.4 2.2 75.5 0.6 0.2 0.1 0.3 0.5 0.5 0.2 0.7 3.3 33.7 0.4 0.1 0.2 0.2 0.0 0.1 0.2 0.6 0.5 0.2 0.6 2.0 0.0 0.1 0.3 0.0 0.1 68.8 0.3 0.1 0.1 2.4 0.1 0.4 0.0 0.1 0.1 0.0 0.2 0.5 0.2 0.0 0.2 0.7 0.0 0.0 0.1 0.0 0.8 0.4 0.4 0.5 0.4 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 1.4 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 1.8 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.5 0.2 0.7 0.2 0.2 0.2 0.1 0.4 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 10.7 3.9 0.0 0.0 0.2 1.8 0.1 0.0 0.0 0.8 0.2 0.3 1.2 21.4 0.1 4.5 0.0 1.1 35.6 0.1 0.0 1.1 8.6 0.0 0.3 0.4 0.0 0.6 0.0 1.8 1.0 0.0 0.0 0.0 3.5 0.1 0.1 29.7 0.4 0.0 0.0 231.1 5.5 0.0 0.0 0.0 0.1 0.7 0.0 0.2 0.1 0.1 0.1 0.1 0.1 9.6 0.0 TMED6 "MGC23911, p24g5, p24gamma5" ENSG00000157315 "Transmembrane p24 trafficking protein 6" Q8WW62 16 69343250-69351786 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "pancreas: 298.9" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 28.3;Exocrine glandular cells: 36.6;Pancreatic endocrine cells: 12.8;Paneth cells: 10.6;Proximal tubular cells: 19.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 15.5;OE19: 7.4" HPA012532 Approved NA NA "Cluster 32: T-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 1: Pancreatic cells - Digestion" "HPA012532: AB_1858065" "unprognostic (6.85e-2)" "unprognostic (1.42e-1)" "unprognostic (6.31e-3)" "prognostic favorable (7.74e-5)" "unprognostic (9.84e-3)" "unprognostic (7.57e-2)" "unprognostic (2.40e-1)" "unprognostic (1.20e-1)" "unprognostic (7.94e-2)" "unprognostic (3.74e-1)" "unprognostic (2.94e-2)" "unprognostic (4.76e-2)" "unprognostic (4.58e-3)" "unprognostic (9.71e-2)" "unprognostic (1.50e-1)" "unprognostic (1.36e-1)" "unprognostic (4.52e-3)" 0.5 0.6 0.1 0.7 0.3 1.1 0.6 0.8 0.7 2.5 0.1 4.3 12.5 0.9 18.1 0.4 22.5 0.7 0.4 0.3 0.0 16.1 5.5 1.9 1.3 0.1 0.1 0.6 298.9 0.1 0.2 0.4 0.1 0.7 7.8 1.0 0.5 2.4 0.3 1.0 7.7 0.5 0.1 0.9 61.2 0.4 0.2 0.2 0.5 0.0 0.6 0.3 0.2 0.4 0.6 1.6 1.4 1.0 0.1 0.0 0.9 2.0 0.1 0.0 0.3 2.2 0.8 4.2 0.7 0.0 0.6 1.1 0.2 0.2 0.4 0.6 1.7 2.1 0.6 15.5 0.1 2.7 0.9 0.2 0.8 0.1 0.3 0.8 0.1 1.9 1.4 0.5 0.3 1.6 1.1 2.9 1.9 7.4 1.4 2.3 1.2 1.6 0.4 1.7 3.2 1.3 2.7 0.9 1.0 0.5 0.5 1.7 1.9 2.2 1.3 0.8 1.4 1.4 1.3 4.5 1.2 2.2 0.7 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.8 0.7 0.3 0.0 0.1 0.1 0.1 0.1 0.2 0.4 0.1 0.0 0.5 1.3 0.5 0.0 0.1 0.1 0.6 0.5 0.5 0.3 0.2 1.5 0.1 1.8 2.1 0.1 0.0 5.0 0.0 6.6 0.1 28.3 0.7 0.4 8.4 3.2 1.4 36.6 0.0 0.1 9.7 5.0 1.3 0.1 0.4 4.7 0.3 0.0 0.8 2.6 0.0 0.8 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.5 0.0 0.5 1.0 12.8 10.6 0.0 0.3 0.3 8.0 19.1 0.4 0.6 0.0 0.5 0.2 0.1 0.1 0.6 0.0 0.1 0.5 0.1 7.0 0.2 TMEM132E DFNB99 ENSG00000181291 "Transmembrane protein 132E" Q6IEE7 17 34579487-34639318 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 17.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 4.1;Inhibitory neurons: 6.4;Oligodendrocyte precursor cells: 13.0;Proximal tubular cells: 11.5" "Cancer enriched" "Detected in some" 4 "glioma: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "RPMI-8226: 37.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070608 Approved Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus,Cytosol" NA NA 170000 "Cluster 40: NK-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Golgi apparatus" "Nuclear bodies, Cytosol" "HPA070608: AB_2686286" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (3.29e-5)" "unprognostic (3.37e-1)" "unprognostic (1.37e-1)" "unprognostic (8.61e-2)" "unprognostic (1.06e-3)" "unprognostic (1.72e-1)" "unprognostic (1.80e-1)" "unprognostic (1.56e-2)" "unprognostic (2.16e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.67e-2)" "unprognostic (1.51e-2)" "unprognostic (2.65e-1)" "unprognostic (8.71e-2)" 0.3 0.1 4.6 0.0 3.0 0.0 0.1 6.1 6.4 0.4 0.0 0.1 1.2 0.1 0.0 0.1 0.1 0.1 0.5 2.6 6.2 3.6 0.4 0.1 0.1 17.9 5.1 0.2 0.0 0.0 0.1 0.1 10.2 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.7 0.1 8.7 0.3 0.1 1.9 6.5 0.0 0.2 0.0 0.1 0.1 0.2 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 4.3 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.2 0.0 0.0 0.0 0.0 4.6 3.0 6.1 6.4 2.6 6.2 17.9 5.1 10.2 8.7 6.5 11.1 0.1 0.0 0.0 2.6 0.1 0.3 0.0 0.0 0.0 1.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 4.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 6.4 0.0 0.0 1.9 0.7 2.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 13.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.1 0.0 0.2 0.5 1.2 2.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 TMEM174 "FLJ31268, MGC13034" ENSG00000164325 "Transmembrane protein 174" Q8WUU8 5 73173193-73175143 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 309 "kidney: 153.2" "Cell type enriched" "Detected in some" 10 "Proximal tubular cells: 160.6" "Cancer enriched" "Detected in single" 126 "renal cancer: 6.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA037975 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA037975: AB_10672732" "unprognostic (8.11e-2)" "prognostic favorable (3.30e-6)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 153.2 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.3 0.1 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.5 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 160.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 TMEM200C TTMA ENSG00000206432 "Transmembrane protein 200C" A6NKL6 18 5882072-5895955 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.7;salivary gland: 5.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 9.3;Cone photoreceptor cells: 6.2;Inhibitory neurons: 8.0;Oligodendrocyte precursor cells: 17.6" "Cancer enhanced" "Detected in single" "glioma: 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.1;NTERA-2: 4.7;PC-3: 22.0;U-2 OS: 10.9;U-251 MG: 3.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA047253, HPA050490" Uncertain Approved Microtubules NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Microtubules "HPA047253: AB_2680001, HPA050490: AB_2681144" "unprognostic (6.57e-4)" "unprognostic (3.09e-1)" "unprognostic (1.05e-2)" "unprognostic (3.74e-2)" "unprognostic (2.13e-1)" "unprognostic (5.07e-2)" "unprognostic (3.20e-1)" "unprognostic (2.07e-1)" "unprognostic (4.12e-2)" "unprognostic (2.29e-2)" "unprognostic (6.31e-2)" "unprognostic (3.82e-4)" "unprognostic (2.48e-10)" "unprognostic (2.94e-2)" "unprognostic (6.38e-2)" "unprognostic (7.22e-2)" "unprognostic (2.38e-2)" 0.2 3.9 2.2 0.3 2.2 0.0 0.6 0.3 2.2 0.7 0.0 0.5 0.1 0.5 1.1 0.2 0.5 0.4 2.1 1.0 2.5 1.6 1.0 0.1 0.4 2.2 7.7 0.7 0.0 0.1 2.3 0.0 2.6 0.7 0.0 0.8 5.5 0.2 0.0 0.2 0.6 0.1 2.5 0.6 0.4 0.9 2.6 0.1 0.1 0.0 0.3 0.4 0.1 0.9 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 22.0 1.3 0.0 0.0 0.0 0.0 1.1 3.5 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 10.9 0.0 3.9 0.0 0.0 0.0 1.5 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.2 0.3 2.2 1.0 2.5 2.2 7.7 2.6 2.5 2.6 0.9 0.1 0.0 1.1 0.3 0.0 0.1 0.0 0.0 0.0 9.3 0.5 2.0 2.4 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.1 2.0 3.4 0.1 0.7 0.0 0.0 1.6 0.0 0.1 2.2 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 8.0 0.0 0.0 0.0 0.4 1.1 1.2 0.2 0.0 1.0 0.0 0.8 0.0 17.6 0.1 0.1 0.0 2.2 0.0 0.0 0.0 0.1 0.2 1.3 0.0 0.0 1.4 0.3 0.4 0.0 0.3 0.0 0.0 0.1 0.0 0.1 TMEM213 ENSG00000214128 "Transmembrane protein 213" A2RRL7 7 138797952-138838101 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 12 "kidney: 76.0;salivary gland: 52.3" "Cell type enhanced" "Detected in some" "Collecting duct cells: 53.3;Distal tubular cells: 144.8;Melanocytes: 26.6" "Cancer enriched" "Detected in some" 22 "renal cancer: 21.7" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "basophil: 2.1;neutrophil: 1.1;NK-cell: 2.0" "Group enriched" "Detected in many" 5 "granulocytes: 2.1;NK-cells: 2.0" "Cell line enhanced" "Detected in single" "RPTEC TERT1: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA054059 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA054059: AB_2682361" "unprognostic (2.79e-2)" "unprognostic (2.56e-1)" "unprognostic (1.85e-2)" "unprognostic (1.19e-2)" "unprognostic (3.19e-2)" "unprognostic (6.84e-2)" "unprognostic (1.17e-2)" "unprognostic (2.10e-1)" "unprognostic (6.14e-2)" "unprognostic (6.08e-2)" "unprognostic (1.91e-2)" "prognostic favorable (5.54e-7)" "unprognostic (4.33e-1)" "unprognostic (9.99e-2)" "unprognostic (3.06e-1)" "unprognostic (1.05e-2)" 0.1 0.1 0.5 0.2 0.5 1.1 4.7 0.6 0.7 2.8 0.4 0.1 1.3 0.2 0.6 0.3 0.1 0.2 0.0 0.6 0.1 76.0 0.1 1.1 0.2 0.2 0.1 0.1 0.6 0.0 0.1 0.1 0.4 0.4 0.1 0.3 52.3 1.2 0.1 5.3 0.3 0.1 0.0 0.2 0.4 0.1 0.5 0.1 0.1 0.0 0.1 0.0 0.0 1.0 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.3 0.0 0.2 0.1 0.0 0.1 2.1 0.2 0.2 0.3 0.2 0.4 0.2 0.1 0.2 0.1 0.3 0.2 0.1 1.1 2.0 0.2 0.2 0.1 0.1 0.5 0.5 0.6 0.7 0.6 0.1 0.2 0.1 0.4 0.0 0.5 1.0 0.1 3.2 9.9 0.0 0.1 0.0 0.9 3.0 0.0 0.4 14.1 7.9 0.4 0.0 4.4 53.3 0.0 0.0 0.2 0.0 144.8 0.0 0.0 0.9 0.4 0.5 0.0 0.0 0.6 0.2 0.1 0.2 0.0 1.3 1.3 0.1 0.0 0.0 0.1 1.7 0.4 0.0 2.0 0.0 0.8 0.0 0.0 0.1 26.6 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.9 3.5 1.3 0.0 0.5 0.2 0.0 0.2 0.0 0.4 0.0 0.6 0.0 0.2 0.6 TMEM266 "C15orf27, FLJ38190" ENSG00000169758 "Transmembrane protein 266" Q2M3C6 15 76059958-76229121 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 8.4;skeletal muscle: 5.8;tongue: 2.2" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 10.4;Cytotrophoblasts: 16.0;Early spermatids: 7.0;Late spermatids: 19.7;Rod photoreceptor cells: 9.1;Sertoli cells: 6.6;Spermatogonia: 6.3" "Cancer enhanced" "Detected in some" "testis cancer: 2.3" "Region enriched" "Detected in many" 5 "cerebellum: 8.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.3" "Region enriched" "Detected in all" 6 "cerebellum: 58.7" "Region enriched" "Detected in many" 5 "cerebellum: 26.8" "HPA041921, HPA049425" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA041921: AB_10796789, HPA049425: AB_2732552" "unprognostic (8.63e-3)" "unprognostic (6.11e-3)" "unprognostic (3.44e-3)" "unprognostic (9.17e-5)" "unprognostic (4.67e-1)" "unprognostic (2.61e-2)" "unprognostic (9.34e-3)" "unprognostic (5.61e-2)" "unprognostic (8.48e-3)" "unprognostic (2.89e-2)" "unprognostic (1.18e-2)" "unprognostic (3.95e-2)" "unprognostic (1.68e-3)" "unprognostic (1.25e-1)" "unprognostic (1.31e-1)" "unprognostic (1.13e-2)" "unprognostic (7.86e-2)" 0.0 0.9 0.9 0.0 1.0 0.0 0.1 8.4 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.5 0.0 0.5 0.1 0.6 0.8 0.0 1.1 0.0 1.2 0.9 0.7 0.1 0.0 1.1 0.0 0.0 5.8 0.5 0.0 0.0 0.5 0.1 0.0 0.6 1.4 0.3 0.0 2.2 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.0 8.4 1.7 1.2 0.9 0.6 0.8 0.7 0.5 1.4 0.8 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 4.3 0.5 0.5 0.0 0.0 0.0 1.8 10.4 16.0 0.0 0.0 1.9 0.0 7.0 0.2 0.1 0.4 0.0 0.0 0.0 0.2 2.2 0.9 1.5 0.1 0.0 0.2 0.4 0.4 4.5 1.7 0.0 0.0 0.0 0.3 0.0 19.7 0.0 0.4 0.0 0.0 0.0 0.5 1.0 0.0 0.0 0.1 0.0 0.7 0.0 1.0 0.0 0.7 1.5 9.1 6.6 1.3 0.2 0.5 6.3 0.0 0.0 5.9 0.2 0.5 0.0 0.7 TMEM82 ENSG00000162460 "Transmembrane protein 82" A0PJX8 1 15742499-15747982 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 24.4;kidney: 11.5;liver: 52.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 42.8;Hepatocytes: 49.3;Paneth cells: 60.2;Proximal enterocytes: 173.6;Proximal tubular cells: 53.3" "Cancer enhanced" "Detected in some" "liver cancer: 10.2;renal cancer: 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "CACO-2: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA060282 Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" Nucleoplasm Cytosol "HPA060282: AB_2684241" "unprognostic (2.46e-2)" "unprognostic (7.96e-2)" "unprognostic (4.88e-2)" "unprognostic (1.40e-2)" "unprognostic (6.45e-2)" "unprognostic (6.90e-2)" "unprognostic (4.80e-2)" "prognostic favorable (3.80e-7)" "unprognostic (1.41e-1)" "unprognostic (5.80e-2)" "unprognostic (4.75e-2)" "unprognostic (1.09e-1)" 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.6 24.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.5 52.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 18.9 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.0 1.6 0.0 42.8 7.9 0.0 0.0 0.0 0.0 0.0 2.4 2.7 0.0 0.2 2.9 0.0 1.5 0.1 0.0 0.0 0.4 49.3 0.1 0.0 0.0 9.2 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 60.2 0.0 0.0 0.0 173.6 53.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.2 0.3 0.0 12.5 0.0 TMIGD1 "TMIGD, UNQ9372" ENSG00000182271 "Transmembrane and immunoglobulin domain containing 1" Q6UXZ0 17 30316333-30334059 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "intestine: 140.5" "Group enriched" "Detected in some" 28 "Distal enterocytes: 291.9;Paneth cells: 125.5;Proximal enterocytes: 476.6" "Cancer enriched" "Detected in single" 5 "colorectal cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA021946 Approved Mitochondria NA NA "Cluster 9: Intestine - Unknown function" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA021946: AB_1858140" "unprognostic (1.28e-1)" "unprognostic (1.30e-1)" "unprognostic (1.61e-1)" 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 80.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.5 0.0 0.0 0.0 0.0 0.0 140.5 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 291.9 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 125.5 0.0 0.0 0.0 476.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 7.5 0.0 TNFAIP8L2 FLJ23467 ENSG00000163154 "TNF alpha induced protein 8 like 2" Q6P589 1 151156649-151159749 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 70.4;Kupffer cells: 65.4;Macrophages: 35.8;monocytes: 34.7;NK-cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 29.8;HL-60: 17.6;HMC-1: 44.1;NB-4: 25.2;THP-1: 95.2;U-937: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062742 Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA062742: " "unprognostic (3.19e-3)" "unprognostic (1.02e-2)" "unprognostic (6.63e-3)" "unprognostic (2.27e-2)" "unprognostic (1.29e-1)" "unprognostic (6.49e-3)" "unprognostic (1.05e-1)" "unprognostic (9.15e-3)" "prognostic favorable (3.64e-4)" "unprognostic (9.54e-2)" "unprognostic (3.32e-2)" "unprognostic (9.03e-2)" "prognostic unfavorable (3.53e-7)" "unprognostic (1.78e-1)" "unprognostic (3.91e-2)" "unprognostic (4.87e-2)" "unprognostic (2.23e-1)" 4.7 4.3 4.9 19.6 5.4 6.1 3.4 5.1 7.5 2.3 5.7 4.5 5.3 1.5 1.4 2.5 2.2 5.5 2.3 4.7 5.2 2.0 5.6 10.8 32.0 6.5 5.7 1.0 1.4 1.2 1.2 6.9 7.0 2.1 6.1 0.9 2.6 1.8 0.8 3.8 7.6 5.4 6.4 39.2 3.4 0.8 6.3 19.2 1.3 2.2 17.7 7.8 1.4 8.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 29.8 0.4 0.0 0.0 17.6 44.1 0.0 0.0 0.0 0.0 0.0 0.4 2.5 0.1 0.1 0.0 0.1 0.4 25.2 0.0 0.0 0.1 5.3 0.1 4.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 95.2 2.5 0.2 0.1 0.1 0.2 0.3 0.0 1.9 0.1 37.8 0.1 317.0 238.8 246.7 103.2 220.2 101.9 78.3 125.7 105.2 265.4 83.2 189.5 137.3 292.3 232.9 210.6 63.0 155.7 249.5 4.9 5.4 5.1 7.5 4.7 5.2 6.5 5.7 7.0 6.4 6.3 8.1 0.3 0.0 1.7 0.0 6.9 0.3 0.0 0.0 0.0 0.8 0.8 0.3 0.1 2.8 1.3 0.0 0.0 0.3 11.1 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 8.8 0.0 0.0 0.5 0.2 0.0 0.0 5.1 0.0 0.7 0.3 70.4 0.0 0.0 0.0 0.0 65.4 12.8 0.4 0.3 35.8 0.0 0.0 34.7 0.0 48.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 1.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.4 10.6 0.0 0.0 0.0 TPPP3 "CGI-38, p20, p25gamma" ENSG00000159713 "Tubulin polymerization promoting protein family member 3" Q9BW30 16 67389809-67393518 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 858.4" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 962.0;Melanocytes: 501.6;Respiratory ciliated cells: 1825.2;Suprabasal keratinocytes: 495.3" "Cancer enhanced" "Detected in all" "endometrial cancer: 61.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 65.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "A549: 59.9;OE19: 40.8;RH-30: 31.1;SCLC-21H: 47.8;SH-SY5Y: 20.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047629, HPA061691" Enhanced Approved "Nucleoli fibrillar center" NA NA 43000 "Cluster 7: Monocytes - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoli fibrillar center" "HPA047629: AB_2680108, HPA061691: " "unprognostic (1.63e-1)" "unprognostic (6.62e-3)" "unprognostic (1.35e-1)" "unprognostic (7.28e-3)" "unprognostic (4.48e-3)" "unprognostic (1.59e-3)" "unprognostic (9.22e-2)" "unprognostic (3.23e-1)" "unprognostic (1.46e-2)" "unprognostic (2.93e-2)" "unprognostic (1.02e-3)" "unprognostic (7.98e-2)" "prognostic unfavorable (8.84e-4)" "unprognostic (3.51e-2)" "unprognostic (9.44e-2)" "unprognostic (9.46e-2)" "unprognostic (1.86e-3)" 44.3 27.1 199.2 8.0 200.1 1.0 81.0 186.0 225.7 50.3 168.7 96.4 23.7 29.3 9.7 99.3 858.4 21.9 81.4 188.1 222.0 60.7 4.4 148.0 4.4 258.7 291.6 8.6 23.9 13.6 40.7 78.5 231.2 18.9 14.1 9.6 39.5 13.3 72.2 170.5 38.0 21.4 223.6 17.7 43.6 15.4 228.3 4.7 18.4 55.8 9.1 32.8 36.4 296.2 0.4 59.9 0.6 0.4 0.4 9.4 0.2 1.7 0.4 0.4 0.9 3.9 12.0 0.0 0.9 0.8 0.2 11.3 9.2 0.0 0.1 0.0 3.5 0.0 1.5 1.7 0.1 0.0 0.0 2.4 0.3 3.6 0.0 1.8 0.6 0.0 0.1 0.0 5.4 0.3 0.0 0.2 1.9 40.8 0.0 0.0 31.1 0.2 0.0 0.0 47.8 20.7 0.0 0.1 2.4 1.5 0.0 0.0 0.0 0.0 0.6 0.7 0.0 0.1 0.0 0.0 2.9 0.0 0.9 0.0 25.4 12.4 0.0 37.6 0.2 0.0 0.0 0.0 33.1 0.1 0.0 0.0 5.8 0.0 65.8 0.3 0.0 9.4 199.2 200.1 186.0 225.7 188.1 222.0 258.7 291.6 231.2 223.6 228.3 296.2 14.7 16.0 129.8 17.0 0.2 303.9 8.8 92.5 5.7 3.8 5.9 5.0 4.1 30.0 160.4 18.4 4.2 8.3 0.2 28.4 5.9 166.8 60.1 962.0 30.9 31.6 177.9 0.0 0.5 1.8 4.3 141.9 7.1 14.7 25.4 1.0 5.0 0.1 2.9 0.0 0.7 65.1 132.2 3.8 82.5 23.7 29.2 13.7 501.6 1.0 10.7 68.7 1.0 1.0 30.0 8.4 39.7 3.4 0.0 5.6 29.8 0.9 1825.2 8.9 236.7 259.3 163.7 8.1 5.8 1.6 495.3 80.0 5.5 0.8 27.3 10.1 TREH "MGC129621, TRE, TREA" ENSG00000118094 Trehalase O43280 11 118657316-118679690 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 66.3" "Group enriched" "Detected in some" 5 "Late spermatids: 315.7;Proximal enterocytes: 186.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "BEWO: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039913, HPA042045" Enhanced Approved Vesicles,Cytosol "Intracellular and membrane" NA NA 12000000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 45: Enterocytes - Digestion" Cytosol Vesicles "HPA039913: AB_10674988, HPA042045: AB_2677817" "unprognostic (1.29e-1)" "unprognostic (1.58e-1)" "unprognostic (1.01e-2)" "unprognostic (5.22e-4)" "unprognostic (2.52e-1)" "unprognostic (9.83e-2)" "prognostic favorable (3.76e-4)" "unprognostic (1.17e-1)" "unprognostic (1.34e-1)" "unprognostic (2.42e-1)" "unprognostic (1.04e-1)" "unprognostic (1.63e-2)" "prognostic favorable (2.33e-6)" "unprognostic (2.09e-2)" "unprognostic (6.30e-2)" "unprognostic (1.22e-1)" "unprognostic (1.15e-1)" 0.7 0.2 1.6 0.3 3.7 0.0 0.4 0.6 3.8 0.3 0.0 1.6 60.0 0.4 0.6 1.6 0.3 2.6 1.0 1.1 2.7 13.4 6.1 0.2 0.1 2.1 2.0 0.2 1.8 0.0 0.3 0.1 1.9 0.5 1.3 0.0 0.2 0.0 0.0 0.1 66.3 0.1 0.6 0.1 1.7 1.8 2.5 0.0 0.4 0.0 0.0 0.4 0.3 6.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.5 0.0 0.4 0.0 0.2 0.0 0.2 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 3.7 0.6 3.8 1.1 2.7 2.1 2.0 1.9 0.6 2.5 6.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.8 0.0 0.0 0.3 0.3 1.5 0.0 1.8 0.0 0.1 0.0 2.3 7.9 0.2 45.6 0.8 1.6 0.1 3.0 0.0 0.1 2.5 0.0 0.3 4.6 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 7.0 0.0 0.0 0.4 315.7 2.1 0.1 0.0 0.0 0.0 0.0 0.0 1.5 5.3 0.9 6.3 1.9 0.1 0.3 186.3 32.8 0.0 0.0 0.0 0.3 0.2 1.7 0.8 2.1 0.0 0.0 0.1 0.0 3.7 0.0 TRIM10 "HERF1, RFB30, RNF9" ENSG00000204613 "Tripartite motif containing 10" Q9UDY6 6 30151943-30161211 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.8;kidney: 2.0;liver: 2.9" "Cell type enriched" "Detected in some" 21 "Erythroid cells: 126.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "HEL: 22.5" "Not detected" "Not detected" "Region enriched" "Detected in single" 11 "hippocampal formation: 3.4" HPA043325 Uncertain NA NA "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "HPA043325: AB_2678428" "unprognostic (2.98e-1)" "unprognostic (3.13e-2)" "unprognostic (2.99e-2)" "unprognostic (2.13e-1)" "unprognostic (2.98e-1)" "unprognostic (9.53e-3)" "unprognostic (6.32e-2)" "unprognostic (2.71e-1)" "unprognostic (2.64e-2)" "unprognostic (1.74e-3)" "unprognostic (1.46e-2)" "unprognostic (4.37e-2)" "unprognostic (1.22e-2)" 0.0 0.0 0.0 0.1 0.0 7.8 0.0 0.0 0.0 0.1 0.0 1.6 1.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.0 2.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.5 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 1.2 126.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 1.9 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 5.9 0.0 0.0 0.0 3.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.3 0.0 TRIM15 "RNF93, ZNF178, ZNFB7" ENSG00000204610 "Tripartite motif containing 15" Q9C019 6 30163206-30172693 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 17.1;kidney: 6.0;liver: 14.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 139.1;Intestinal goblet cells: 41.5;Paneth cells: 332.0;Proximal enterocytes: 80.0" "Group enriched" "Detected in many" 4 "colorectal cancer: 14.4;liver cancer: 5.6;pancreatic cancer: 7.7;renal cancer: 4.4;stomach cancer: 8.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "HEL: 16.5;Hep G2: 7.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047527 Approved "Centriolar satellite,Cytosol" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 36: HEL - Hemostasis" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Centriolar satellite" "HPA047527: " "unprognostic (2.61e-1)" "unprognostic (1.54e-1)" "unprognostic (1.85e-1)" "unprognostic (1.71e-1)" "unprognostic (5.36e-2)" "unprognostic (1.92e-2)" "unprognostic (7.57e-4)" "unprognostic (5.27e-2)" "unprognostic (1.11e-1)" "unprognostic (4.00e-2)" "unprognostic (2.16e-2)" "unprognostic (2.19e-2)" "unprognostic (3.83e-1)" "unprognostic (1.63e-1)" "unprognostic (2.41e-1)" 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 13.8 17.1 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 6.0 14.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.7 12.2 0.3 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.5 0.1 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 11.5 0.0 0.0 0.0 0.0 0.0 139.1 1.9 1.8 0.0 0.0 0.1 0.0 0.0 2.7 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 41.5 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 332.0 0.0 0.0 0.0 80.0 21.5 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.0 0.0 0.5 0.0 29.1 0.0 TRIM63 "IRF, MURF-1, RNF28, SMRZ" ENSG00000158022 "Tripartite motif containing 63" Q969Q1 1 26051301-26068436 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Muscle protein, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 1935.8" "Cell type enriched" "Detected in some" 7 "Cardiomyocytes: 272.2" "Cancer enriched" "Detected in some" 10 "melanoma: 31.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 40 "ASC diff: 16.1;SK-MEL-30: 55.7" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 5.1" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (1.10e-1)" "unprognostic (4.80e-4)" "unprognostic (1.45e-2)" "unprognostic (7.52e-3)" "unprognostic (1.44e-1)" "unprognostic (2.05e-2)" "unprognostic (3.42e-1)" "unprognostic (1.12e-1)" "unprognostic (2.71e-1)" "unprognostic (1.06e-1)" "unprognostic (3.17e-1)" "unprognostic (1.01e-1)" "unprognostic (2.16e-2)" "unprognostic (5.90e-2)" "unprognostic (1.33e-2)" "unprognostic (2.32e-1)" "unprognostic (5.58e-2)" 1.2 0.2 0.0 0.0 0.1 0.0 0.8 0.0 0.1 1.5 0.0 0.7 0.3 8.8 0.3 7.1 0.6 2.7 243.0 0.0 0.0 1.5 0.4 1.3 0.0 0.1 0.1 0.2 0.8 0.0 0.2 4.0 0.0 1.5 0.2 0.1 9.6 0.4 1935.8 4.2 0.8 3.5 0.0 0.2 0.8 0.2 0.2 0.3 0.5 387.6 0.2 8.9 1.1 0.1 0.0 0.0 0.0 0.0 16.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.9 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.6 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.4 0.0 272.2 5.7 0.0 1.8 0.0 0.5 0.0 0.0 1.9 1.8 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.1 8.1 0.0 0.1 10.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 12.4 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 3.3 29.7 0.0 0.0 0.0 34.7 1.4 0.0 0.0 0.0 0.1 1.6 6.1 0.0 0.1 0.1 TRIM71 "LIN-41, LIN41" ENSG00000206557 "Tripartite motif containing 71" Q2Q1W2 3 32817997-32897824 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "RNA-mediated gene silencing, Ubl conjugation pathway" "Developmental protein, RNA-binding, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 4.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Extravillous trophoblasts: 15.6;Inhibitory neurons: 4.5;Oligodendrocyte precursor cells: 4.5;Spermatogonia: 13.7" "Cancer enriched" "Detected in some" 28 "testis cancer: 28.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 31.4;BEWO: 94.5;Hep G2: 63.8;NTERA-2: 84.3;SuSa: 76.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA038141, HPA038142" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Actin filaments, Focal adhesion sites" "HPA038141: AB_2675857, HPA038142: AB_10697240" "unprognostic (2.93e-2)" "unprognostic (4.29e-3)" "unprognostic (1.70e-1)" "unprognostic (1.02e-2)" "unprognostic (2.58e-2)" "unprognostic (3.27e-2)" "unprognostic (2.09e-2)" "unprognostic (1.25e-1)" "unprognostic (3.16e-2)" "unprognostic (3.04e-1)" "unprognostic (1.11e-2)" "unprognostic (3.11e-1)" "unprognostic (4.36e-6)" "unprognostic (3.92e-2)" "unprognostic (9.27e-2)" "unprognostic (8.17e-2)" "unprognostic (4.65e-2)" 0.0 0.0 1.0 0.0 1.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 0.9 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 31.4 0.0 0.0 0.0 94.5 0.0 0.0 0.0 0.0 23.1 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 1.6 0.0 63.8 0.0 1.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.4 0.0 0.0 0.6 6.9 84.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 76.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 0.8 0.9 0.8 0.1 0.1 0.1 0.0 0.8 0.2 0.0 9.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.1 0.0 2.7 0.0 1.8 0.0 0.0 3.9 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.2 0.0 0.0 3.1 0.0 15.6 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 4.5 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 1.0 0.1 0.0 0.0 4.5 0.1 0.0 0.0 0.4 0.0 0.0 0.0 3.6 0.7 0.5 0.0 0.0 0.1 0.3 13.7 0.0 0.0 4.0 0.1 0.0 0.0 0.0 TRPM3 "GON-2, KIAA1616, LTRPC3" ENSG00000083067 "Transient receptor potential cation channel subfamily M member 3" Q9HCF6 9 70529060-71446904 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "choroid plexus: 801.0" "Cell type enhanced" "Detected in many" "Astrocytes: 905.0;Excitatory neurons: 390.3;Inhibitory neurons: 186.9;Muller glia cells: 184.5" "Cancer enhanced" "Detected in single" "renal cancer: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "HAP1: 17.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA072650, HPA074393" Enhanced Approved Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA072650: , HPA074393: " "unprognostic (3.74e-1)" "unprognostic (6.30e-2)" "unprognostic (4.79e-2)" "unprognostic (4.81e-2)" "unprognostic (1.38e-2)" "unprognostic (8.88e-2)" "unprognostic (1.49e-2)" "unprognostic (2.19e-2)" "unprognostic (1.11e-1)" "unprognostic (1.89e-2)" "unprognostic (6.10e-2)" "unprognostic (1.15e-2)" "unprognostic (1.82e-7)" "unprognostic (3.51e-2)" "unprognostic (5.64e-2)" "unprognostic (1.74e-2)" "unprognostic (1.50e-2)" 0.7 0.6 22.0 0.1 30.4 0.2 0.1 40.5 9.6 1.0 801.0 0.2 0.8 1.1 1.3 0.1 0.4 0.4 0.8 39.3 27.8 16.5 0.2 0.1 0.1 36.7 46.8 3.6 0.5 0.0 2.9 0.1 20.8 0.5 0.1 23.0 0.1 2.5 0.3 0.1 0.0 0.2 25.2 0.3 0.6 5.1 41.6 0.2 0.9 0.1 0.0 0.1 0.4 15.4 0.0 0.0 0.9 0.0 1.1 2.6 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 17.2 0.0 0.1 0.0 0.1 0.1 1.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 2.3 0.2 0.0 0.0 1.0 4.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.2 0.0 0.9 0.0 1.1 0.0 0.2 0.0 0.3 0.2 0.0 0.0 3.1 0.0 0.1 3.1 0.0 0.0 0.0 0.0 0.4 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 22.0 30.4 40.5 9.6 39.3 27.8 36.7 46.8 20.8 25.2 41.6 15.4 0.3 3.2 3.0 905.0 0.5 0.4 0.9 0.0 0.6 16.4 0.3 0.5 5.3 5.7 2.5 16.5 66.7 0.1 0.2 0.1 5.9 0.1 4.8 1.4 1.0 1.3 15.4 0.0 390.3 0.2 0.1 3.0 0.0 3.2 0.0 1.4 0.7 0.3 0.2 1.7 186.9 0.1 0.0 0.9 1.4 2.3 5.6 0.8 0.0 56.2 0.2 184.5 1.0 105.6 8.3 0.1 0.1 9.1 0.0 0.5 0.1 33.3 0.8 10.1 0.0 3.5 1.3 1.3 0.6 0.0 0.9 0.3 0.9 0.6 0.0 0.3 TST RDS ENSG00000128311 "Thiosulfate sulfurtransferase" Q16762 22 37010859-37020183 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 561.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 565.8;Hepatocytes: 414.9;Paneth cells: 463.4;Proximal enterocytes: 278.5;Proximal tubular cells: 254.5;Undifferentiated cells: 217.4" "Cancer enhanced" "Detected in all" "liver cancer: 177.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.0" "Group enriched" "Detected in all" 6 "dendritic cells: 25.0;granulocytes: 21.8;monocytes: 17.7" "Cell line enhanced" "Detected in many" "OE19: 264.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003044, HPA003643, CAB009546" Enhanced Supported Mitochondria NA NA 560000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "CAB009546: AB_2211220, HPA003044: AB_1858417, HPA003643: AB_1080411" "unprognostic (3.09e-2)" "unprognostic (2.70e-1)" "unprognostic (2.07e-1)" "unprognostic (1.21e-2)" "unprognostic (2.36e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-2)" "unprognostic (2.38e-2)" "unprognostic (2.32e-1)" "unprognostic (7.96e-3)" "unprognostic (4.38e-2)" "unprognostic (1.78e-1)" "prognostic favorable (7.59e-6)" "unprognostic (6.08e-3)" "unprognostic (3.46e-1)" "unprognostic (1.16e-1)" "prognostic favorable (1.04e-4)" 51.4 154.1 31.3 20.9 40.5 27.1 37.3 38.2 36.0 34.1 31.3 190.7 147.7 18.9 2.9 96.7 25.7 75.9 69.9 29.1 33.1 100.8 561.2 22.7 8.1 34.4 35.2 26.9 63.6 9.4 12.4 7.9 34.4 26.4 80.3 1.3 39.8 18.2 52.9 33.8 114.2 13.2 35.4 16.9 88.4 8.1 35.8 4.3 17.1 34.9 16.2 30.0 56.7 39.0 42.6 86.1 10.8 36.8 25.9 10.6 21.4 23.0 18.6 12.6 18.3 25.4 25.7 11.1 18.8 17.0 11.9 35.1 7.9 22.3 2.7 33.6 50.0 11.5 15.5 49.7 64.9 16.4 26.4 20.1 23.9 9.1 7.6 17.5 31.1 5.9 14.2 18.2 6.0 90.8 0.5 49.9 18.7 264.4 39.3 37.0 11.7 19.7 35.9 36.7 6.4 17.1 24.2 41.4 31.7 10.2 43.4 39.3 25.1 14.0 27.2 24.2 7.4 14.0 15.4 3.4 5.3 46.4 8.5 10.9 17.7 8.0 0.8 4.7 1.7 2.8 0.8 0.6 25.0 1.7 0.4 0.2 21.8 3.7 1.5 1.7 2.1 8.1 31.3 40.5 38.2 36.0 29.1 33.1 34.4 35.2 34.4 35.4 35.8 39.0 13.9 28.9 74.8 10.1 7.8 1.3 9.5 20.4 12.0 1.3 32.7 16.6 39.2 170.1 23.7 20.2 0.0 11.6 2.5 565.8 46.9 45.3 1.9 53.3 30.2 13.4 34.3 35.3 0.3 44.0 6.4 14.6 126.9 74.3 14.0 60.9 39.3 414.9 15.1 1.7 0.5 162.8 8.2 28.9 6.8 3.5 13.1 23.2 1.8 1.0 18.6 27.3 3.1 3.5 7.4 36.8 463.4 7.9 24.5 10.5 278.5 254.5 19.2 0.8 0.0 10.7 11.5 2.4 0.5 39.8 2.4 11.4 5.0 57.5 217.4 17.3 TTC36 HBP21 ENSG00000172425 "Tetratricopeptide repeat domain 36" A6NLP5 11 118527472-118531197 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "liver: 171.5" "Group enriched" "Detected in many" 13 "Hepatocytes: 492.9;Proximal enterocytes: 185.5;Proximal tubular cells: 172.9" "Group enriched" "Detected in some" 7 "breast cancer: 5.0;liver cancer: 12.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "SK-BR-3: 9.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA038731 Enhanced Uncertain Nucleoplasm NA NA 100000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "HPA038731: AB_10672651" "unprognostic (1.57e-3)" "unprognostic (2.58e-3)" "unprognostic (1.16e-1)" "unprognostic (6.50e-2)" "unprognostic (1.02e-2)" "unprognostic (2.17e-1)" "prognostic favorable (1.81e-5)" "unprognostic (6.32e-2)" "unprognostic (8.80e-2)" "unprognostic (6.14e-2)" "unprognostic (4.77e-3)" "unprognostic (3.38e-2)" "unprognostic (5.77e-7)" "unprognostic (5.60e-2)" "unprognostic (2.24e-1)" "unprognostic (1.59e-1)" "unprognostic (8.95e-3)" 8.0 1.3 0.8 0.1 0.8 0.0 11.1 0.8 0.7 0.3 0.7 0.5 5.9 0.4 18.5 0.5 0.5 0.1 1.0 0.3 0.6 8.9 171.5 0.3 0.1 1.1 0.7 0.6 1.2 0.0 1.6 0.1 0.6 1.0 0.0 0.3 0.9 0.0 1.4 0.5 4.1 0.0 0.6 0.2 0.7 0.8 0.6 0.0 0.7 0.4 0.0 0.5 0.3 1.0 0.0 0.0 0.1 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.5 0.2 0.7 0.0 0.0 0.2 0.0 0.0 9.7 0.0 0.0 0.8 0.0 0.3 0.0 0.5 0.0 0.1 0.0 0.4 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 0.8 0.8 0.7 0.3 0.6 1.1 0.7 0.6 0.6 0.6 1.0 0.3 0.0 0.0 0.3 2.4 0.3 0.6 0.2 0.6 0.1 21.2 11.3 0.3 11.5 0.1 12.9 0.0 1.5 0.1 0.8 17.6 0.2 0.1 1.2 0.6 1.1 2.4 16.4 0.2 0.5 0.2 0.3 2.0 1.7 0.0 0.4 9.7 492.9 0.1 0.0 0.3 9.3 0.0 14.2 0.3 0.2 0.3 0.9 0.0 0.0 0.6 1.1 0.0 0.0 0.1 0.2 7.6 0.0 0.3 1.9 185.5 172.9 0.2 0.8 0.0 0.2 0.2 0.3 0.3 0.3 0.1 2.1 1.1 0.4 11.7 1.3 TTC38 FLJ20699 ENSG00000075234 "Tetratricopeptide repeat domain 38" Q5R3I4 22 46267961-46294008 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 233.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 134.2;NK-cells: 182.3;Proximal enterocytes: 144.5;Proximal tubular cells: 149.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 90.5" "Group enriched" "Detected in all" 4 "granulocytes: 29.9;NK-cells: 38.0;T-cells: 90.5" "Cell line enhanced" "Detected in many" "Hep G2: 76.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029302, HPA075893" Approved Approved Cytosol NA NA 170000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA029302: AB_10601704, HPA075893: " "unprognostic (7.78e-2)" "unprognostic (5.85e-2)" "unprognostic (4.92e-3)" "prognostic favorable (3.21e-6)" "unprognostic (8.34e-2)" "unprognostic (6.38e-2)" "unprognostic (8.72e-2)" "unprognostic (3.62e-2)" "unprognostic (9.45e-2)" "unprognostic (7.22e-2)" "unprognostic (1.12e-1)" "unprognostic (5.66e-2)" "unprognostic (7.34e-3)" "unprognostic (9.02e-2)" "unprognostic (4.12e-1)" "unprognostic (4.97e-1)" "unprognostic (8.33e-2)" 24.7 23.6 9.5 10.2 11.6 46.9 25.7 10.3 10.7 16.8 12.8 42.1 79.4 13.8 6.4 12.5 17.2 15.5 23.2 9.7 11.0 64.4 233.6 15.6 10.7 13.3 12.3 26.0 35.5 7.6 13.2 7.8 11.9 23.6 31.9 4.7 27.0 7.3 20.6 12.2 80.9 10.3 10.3 22.8 29.1 6.8 12.2 2.5 15.2 12.3 5.9 16.9 13.5 11.3 12.0 13.2 16.4 34.5 15.2 13.1 15.7 17.2 11.5 18.7 14.6 21.8 8.5 0.1 10.8 17.9 7.4 10.8 16.8 13.9 6.8 27.0 36.9 15.6 28.4 76.0 21.0 9.0 59.8 22.6 7.3 8.5 9.7 12.9 15.9 0.2 11.9 19.4 12.2 12.1 0.3 28.2 12.5 22.6 13.1 0.0 8.0 8.0 12.6 13.8 2.9 22.8 23.7 16.3 13.3 7.5 26.1 18.0 18.5 13.0 14.1 10.3 11.0 14.7 9.2 1.7 8.8 13.7 13.8 29.9 11.9 22.5 90.5 11.4 9.7 2.3 8.5 41.0 10.8 1.7 3.5 36.9 7.6 38.0 8.7 4.3 4.5 42.5 9.5 11.6 10.3 10.7 9.7 11.0 13.3 12.3 11.9 10.3 12.2 11.3 9.2 0.0 7.5 13.7 6.5 3.3 5.9 4.3 3.4 2.6 10.2 6.7 9.2 38.6 4.3 9.2 6.2 10.4 69.1 69.0 23.5 10.4 0.3 7.4 9.6 8.9 20.9 10.5 0.3 10.2 9.3 7.5 11.7 6.9 17.2 13.3 9.7 134.2 13.4 5.0 1.8 37.8 4.1 14.9 4.3 0.9 7.5 9.6 5.4 9.4 12.8 9.3 182.3 5.5 5.6 9.7 51.6 13.9 16.2 8.6 144.5 149.6 5.3 5.4 6.6 7.4 5.9 1.8 3.7 5.3 8.2 6.4 29.2 22.7 51.7 4.6 TUBA4B "FLJ13940, TUBA4" ENSG00000243910 "Tubulin alpha 4b" Q9H853 2 219253243-219272197 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 8 "fallopian tube: 40.0" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 148.9;Respiratory ciliated cells: 83.1" "Cancer enriched" "Detected in some" 6 "endometrial cancer: 8.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (3.20e-5)" "unprognostic (1.47e-4)" "unprognostic (1.85e-1)" "unprognostic (3.70e-3)" "unprognostic (9.63e-2)" "unprognostic (8.97e-2)" "unprognostic (2.18e-3)" "unprognostic (7.32e-2)" "unprognostic (9.50e-2)" "unprognostic (6.56e-2)" "unprognostic (2.50e-1)" "unprognostic (2.12e-1)" "unprognostic (2.41e-3)" "unprognostic (3.78e-2)" "unprognostic (9.57e-2)" "unprognostic (3.91e-2)" "unprognostic (4.08e-1)" 0.0 0.0 0.8 0.0 0.6 0.0 0.0 0.2 0.1 1.5 4.7 0.0 0.1 0.5 0.7 0.0 40.0 0.0 0.0 0.4 0.8 1.5 0.2 3.5 0.1 1.9 3.6 0.1 0.0 0.0 0.8 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 1.8 0.0 0.0 0.1 0.7 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.4 0.1 0.1 0.2 0.2 0.3 0.3 0.0 0.2 0.3 0.3 0.6 0.1 0.1 0.0 0.3 1.4 0.8 0.6 0.2 0.1 0.4 0.8 1.9 3.6 1.8 1.8 0.7 1.4 0.0 0.0 3.2 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.9 0.0 4.3 1.8 0.0 0.0 0.0 0.0 1.9 0.0 1.8 148.9 0.9 0.1 1.8 0.0 0.3 0.2 0.0 0.2 0.0 2.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 27.9 83.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 TUBAL3 FLJ21665 ENSG00000178462 "Tubulin alpha like 3" A6NHL2 10 5393101-5404828 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 28.3" "Group enriched" "Detected in some" 4 "Distal enterocytes: 19.8;Proximal enterocytes: 19.7" "Cancer enriched" "Detected in some" 4 "colorectal cancer: 3.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HEL: 13.3;JURKAT: 7.7;K-562: 4.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA045900, HPA063394" Uncertain NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 36: HEL - Hemostasis" "Cluster 45: Enterocytes - Digestion" "HPA045900: AB_10961130, HPA063394: AB_2685003" "unprognostic (2.63e-1)" "unprognostic (1.69e-2)" "unprognostic (5.33e-2)" "unprognostic (1.09e-1)" "unprognostic (7.59e-2)" "unprognostic (2.13e-2)" "unprognostic (3.02e-2)" "unprognostic (4.02e-1)" "unprognostic (1.02e-1)" "unprognostic (2.68e-2)" "unprognostic (1.26e-1)" "unprognostic (3.44e-1)" "unprognostic (4.52e-2)" "unprognostic (2.75e-1)" "unprognostic (1.35e-4)" "unprognostic (7.93e-4)" 0.1 0.0 0.4 0.5 0.3 0.1 0.4 0.4 0.6 0.1 1.4 11.9 24.3 0.0 0.0 0.3 0.2 0.1 0.7 0.3 0.4 5.8 0.0 0.2 0.1 0.8 0.5 0.0 0.0 0.0 0.0 0.1 0.9 0.1 10.8 0.0 0.8 0.0 0.1 0.3 28.3 0.3 0.6 0.0 0.2 1.0 0.8 0.3 0.0 1.4 0.0 0.1 0.2 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.7 0.0 1.2 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 13.3 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 7.7 4.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.4 0.6 0.3 0.4 0.8 0.5 0.9 0.6 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 19.8 0.0 0.0 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.9 0.0 0.0 0.0 19.7 4.4 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.5 0.1 0.0 1.4 0.1 TYRO3 "Brt, Dtk, Etk-2, Rek, RSE, Sky, Tif" ENSG00000092445 "TYRO3 protein tyrosine kinase" Q06418 15 41557675-41583589 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.0;ovary: 49.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 42.4;Leydig cells: 44.4;Oligodendrocyte precursor cells: 29.1;Oligodendrocytes: 46.8;Peritubular cells: 47.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.5" "Cell line enhanced" "Detected in many" "BEWO: 69.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071245 Approved NA NA 17000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 21: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA071245: AB_2686371" "unprognostic (1.26e-1)" "unprognostic (6.34e-2)" "unprognostic (1.47e-1)" "unprognostic (2.68e-1)" "unprognostic (3.29e-1)" "unprognostic (6.77e-2)" "unprognostic (1.56e-3)" "unprognostic (5.41e-2)" "unprognostic (3.72e-1)" "unprognostic (3.21e-1)" "unprognostic (2.69e-1)" "unprognostic (1.37e-1)" "unprognostic (1.92e-10)" "unprognostic (7.59e-2)" "unprognostic (5.22e-1)" "unprognostic (4.04e-3)" "unprognostic (1.84e-2)" 21.5 3.5 18.2 1.4 30.3 0.8 5.2 17.7 27.1 2.1 0.0 2.3 1.6 4.6 3.5 13.1 11.5 2.5 2.2 27.7 10.7 11.3 0.8 3.3 1.3 20.9 22.6 49.7 9.8 0.9 0.9 5.7 18.6 2.6 0.9 2.6 1.9 6.1 0.9 13.8 2.4 4.4 14.4 5.5 3.2 18.8 15.7 0.4 1.1 1.8 3.7 2.1 4.1 32.0 10.3 6.7 20.7 22.7 18.9 12.8 69.2 14.6 9.3 14.2 13.1 37.7 3.4 0.4 18.3 11.9 19.9 23.7 23.3 3.6 6.5 5.8 15.5 3.2 20.2 18.1 13.3 5.2 0.4 4.1 7.3 10.9 3.6 5.8 10.6 9.8 19.1 4.3 7.9 9.8 2.4 1.0 47.7 16.0 6.7 31.9 18.6 3.8 1.2 19.7 24.6 7.0 13.7 21.6 16.3 29.8 17.8 6.0 8.4 28.0 12.2 21.0 22.5 1.7 3.5 3.1 17.2 33.8 17.2 1.1 0.2 0.2 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.3 0.2 0.2 1.5 0.3 0.1 0.3 0.1 0.1 18.2 30.3 17.7 27.1 27.7 10.7 20.9 22.6 18.6 14.4 15.7 32.0 3.4 3.2 1.1 17.6 0.9 6.8 8.5 0.4 0.6 2.7 2.2 2.2 2.9 2.8 0.7 3.7 6.2 2.9 1.1 1.3 0.0 3.9 3.6 1.1 13.0 5.4 1.8 0.0 42.4 3.6 10.2 10.5 8.6 1.9 0.0 7.6 9.7 0.4 1.2 0.0 4.6 0.9 0.0 1.9 1.3 5.1 44.4 0.9 8.8 1.0 0.1 8.3 1.0 29.1 46.8 4.6 0.1 47.0 0.3 6.4 1.2 1.2 0.5 4.0 0.0 3.9 4.3 4.0 6.5 4.2 10.9 18.9 0.7 5.8 2.3 5.7 UBE2QL1 FLJ25076 ENSG00000215218 "Ubiquitin conjugating enzyme E2 Q family like 1" A1L167 5 6448859-6496723 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 26.1;heart muscle: 16.8;retina: 28.3;skeletal muscle: 54.5;tongue: 13.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 30.0;Cardiomyocytes: 27.6;Excitatory neurons: 47.8;Granulosa cells: 45.5;Horizontal cells: 45.4;Inhibitory neurons: 35.3;Rod photoreceptor cells: 63.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 29.7;PC-3: 24.6;SCLC-21H: 23.1;U-266/70: 54.4;U-266/84: 52.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057414 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Plasma membrane" "HPA057414: " "unprognostic (1.45e-2)" "unprognostic (1.58e-2)" "unprognostic (1.79e-2)" "unprognostic (2.10e-1)" "unprognostic (1.08e-2)" "unprognostic (7.43e-2)" "unprognostic (1.15e-2)" "unprognostic (1.36e-1)" "unprognostic (3.10e-1)" "unprognostic (7.16e-2)" "unprognostic (2.15e-3)" "unprognostic (8.41e-2)" "prognostic favorable (6.81e-8)" "unprognostic (3.18e-3)" "unprognostic (2.81e-1)" "unprognostic (1.27e-2)" "unprognostic (1.41e-2)" 1.2 1.4 14.3 0.4 14.6 0.0 1.1 16.5 26.1 2.1 1.8 5.3 0.3 0.8 1.0 0.4 0.7 0.4 16.8 17.9 11.4 3.4 1.2 0.1 0.1 12.0 7.9 2.6 0.6 0.1 3.2 0.0 11.6 3.5 0.3 28.3 0.8 5.5 54.5 1.5 1.4 0.7 5.6 0.2 2.9 0.7 10.1 0.3 1.2 13.9 0.2 0.3 1.3 17.7 0.1 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 29.7 0.0 5.3 0.0 0.0 0.3 0.0 24.6 0.1 0.0 11.5 0.0 0.0 23.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 54.4 52.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 14.6 16.5 26.1 17.9 11.4 12.0 7.9 11.6 5.6 10.1 17.7 0.2 0.0 0.0 5.5 0.3 1.3 0.5 0.5 0.0 30.0 0.4 1.0 27.6 0.0 0.0 0.0 6.2 0.0 0.0 0.0 5.9 0.0 0.0 0.2 0.4 1.0 5.4 0.0 47.8 0.2 0.0 3.6 1.1 0.1 0.0 45.5 0.0 1.0 0.1 45.4 35.3 0.0 0.0 0.3 0.3 0.3 4.1 0.1 0.0 2.8 0.0 9.4 0.0 12.1 5.4 0.1 0.0 6.8 1.8 0.9 0.0 0.2 0.0 63.6 0.0 3.2 1.4 0.1 0.3 0.0 0.1 0.0 0.0 0.5 0.0 0.0 UCN3 "SPC, UCNIII" ENSG00000178473 "Urocortin 3" Q969E3 10 5364966-5374692 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 8.8;pancreas: 5.8;stomach 1: 3.4" "Cell type enriched" "Detected in some" 29 "Enteroendocrine cells: 242.5" "Cancer enhanced" "Detected in many" "pancreatic cancer: 15.4" "Region enhanced" "Detected in some" "medulla oblongata: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "SCLC-21H: 1.2" "Region enhanced" "Detected in some" "hypothalamus: 5.1" HPA038281 Uncertain "Secreted to blood" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA038281: AB_10672408" "unprognostic (2.00e-2)" "unprognostic (2.31e-1)" "unprognostic (1.60e-1)" "unprognostic (2.10e-1)" "unprognostic (3.18e-3)" "unprognostic (8.42e-2)" "unprognostic (3.55e-2)" "unprognostic (2.91e-2)" 0.0 0.8 1.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 2.3 8.8 0.0 0.0 0.0 1.0 1.0 0.0 0.0 0.8 0.7 0.0 0.6 0.0 1.9 0.5 0.0 5.8 0.0 2.7 0.1 0.1 0.3 2.3 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.1 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.1 0.0 0.8 1.9 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.1 242.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.3 0.0 0.0 0.3 0.6 2.9 0.7 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.2 UGT1A7 UGT1G ENSG00000244122 "UDP glucuronosyltransferase family 1 member A7" Q9HAW7 2 233681938-233773299 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "esophagus: 83.8" "Cell type enriched" "Detected in some" 4 "Squamous epithelial cells: 40.7" "Group enriched" "Detected in some" 10 "cervical cancer: 1.2;head and neck cancer: 2.3;lung cancer: 3.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "SiHa: 112.2" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (6.27e-2)" "unprognostic (1.02e-1)" "unprognostic (7.76e-2)" "unprognostic (1.03e-2)" "unprognostic (1.09e-1)" "unprognostic (7.92e-2)" "unprognostic (1.71e-7)" "unprognostic (2.14e-1)" "unprognostic (4.57e-2)" 0.1 1.3 0.2 0.0 0.2 0.0 0.4 0.5 0.8 1.2 0.4 0.3 0.2 0.0 0.0 83.8 0.0 0.0 0.0 0.3 0.2 0.7 4.3 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 5.6 0.0 0.0 3.6 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 5.2 0.4 7.1 1.0 0.0 1.8 0.1 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 112.2 7.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.8 0.3 0.2 0.2 0.5 0.2 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.4 2.3 1.3 4.6 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.8 0.7 0.3 0.2 0.0 0.0 0.0 0.2 0.0 0.0 40.7 1.7 0.0 0.0 0.0 0.5 8.5 UGT1A9 "HLUGP4, LUGP4, UGT1AI" ENSG00000241119 "UDP glucuronosyltransferase family 1 member A9" O60656 2 233671898-233773300 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 370 "kidney: 458.6;liver: 195.6" "Group enriched" "Detected in some" 11 "Hepatocytes: 7.5;Proximal tubular cells: 6.6" "Group enriched" "Detected in some" 157 "liver cancer: 16.1;renal cancer: 16.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "A549: 1.4;RT4: 1.2" NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.46e-2)" "unprognostic (3.56e-1)" "prognostic unfavorable (5.04e-5)" "unprognostic (4.26e-2)" "unprognostic (1.60e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 458.6 195.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT2B10 ENSG00000109181 "UDP glucuronosyltransferase family 2 member B10" P36537 4 68815994-68832023 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 149 "liver: 233.7" "Cell type enriched" "Detected in some" 11 "Hepatocytes: 245.3" "Cancer enriched" "Detected in single" 296 "liver cancer: 93.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 116 "Hep G2: 12.0" HPA045108 Uncertain NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA045108: AB_2679218" "unprognostic (3.50e-3)" "unprognostic (1.92e-3)" "unprognostic (4.17e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 233.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 21.0 0.1 0.0 0.3 0.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 245.3 0.0 0.0 0.0 0.3 0.0 7.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.4 0.0 0.2 0.0 UGT3A1 FLJ34658 ENSG00000145626 "UDP glycosyltransferase family 3 member A1" Q6NUS8 5 35951006-36001028 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "kidney: 51.1;liver: 58.0" "Cell type enhanced" "Detected in some" "Collecting duct cells: 49.7;Early spermatids: 125.9;Hepatocytes: 72.1;Late spermatids: 24.5;Proximal tubular cells: 87.0" "Group enriched" "Detected in some" 15 "liver cancer: 6.7;renal cancer: 4.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 42 "RH-30: 28.2" "HPA047697, HPA056290" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "HPA047697: AB_2680122, HPA056290: AB_2683088" "unprognostic (2.41e-3)" "unprognostic (4.47e-1)" "unprognostic (4.04e-1)" "unprognostic (4.62e-1)" "unprognostic (1.42e-2)" "unprognostic (6.05e-2)" "unprognostic (9.14e-2)" "unprognostic (1.76e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 51.1 58.0 0.0 0.0 0.1 0.0 0.2 0.0 0.4 0.2 0.0 0.1 0.3 0.0 0.7 0.1 0.2 3.0 0.0 6.7 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.4 0.0 0.0 49.7 0.0 0.0 0.0 0.0 3.9 0.0 125.9 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.8 72.1 0.1 0.0 0.3 0.7 0.0 2.6 0.0 24.5 0.9 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 2.5 0.4 0.0 0.0 3.8 87.0 0.0 0.2 6.6 0.0 0.0 4.4 0.8 0.0 0.0 0.0 0.5 0.0 1.8 0.1 UGT3A2 ENSG00000168671 "UDP glycosyltransferase family 3 member A2" Q3SY77 5 36035021-36071358 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.5;lymphoid tissue: 14.7;skin 1: 10.3" "Group enriched" "Detected in some" 4 "Collecting duct cells: 3.7;Early spermatids: 4.4;Late spermatids: 8.2;Proximal tubular cells: 3.8" "Cancer enriched" "Detected in some" 5 "testis cancer: 4.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 6.8;JURKAT: 6.3;MOLT-4: 12.4;REH: 29.9;SuSa: 11.8;T-47d: 7.2;THP-1: 18.0" "Low region specificity" "Detected in many" HPA059475 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" Yes NA "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Golgi apparatus, Cytosol" "HPA059475: AB_2684031" "unprognostic (1.83e-4)" "unprognostic (9.94e-2)" "unprognostic (8.87e-2)" "unprognostic (4.82e-4)" "unprognostic (3.18e-1)" "unprognostic (3.52e-2)" "unprognostic (1.56e-1)" "unprognostic (6.08e-2)" "unprognostic (2.04e-1)" "unprognostic (8.13e-2)" "unprognostic (7.49e-2)" "unprognostic (4.17e-2)" "unprognostic (1.36e-3)" "unprognostic (6.65e-2)" "unprognostic (7.52e-2)" "unprognostic (7.38e-2)" "unprognostic (4.52e-3)" 0.0 0.8 0.0 0.0 0.0 6.5 1.1 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.3 2.6 0.6 0.0 0.0 1.0 1.1 0.0 0.0 0.1 0.9 0.2 1.2 0.4 0.0 0.1 0.1 0.0 0.1 10.3 0.0 0.0 0.1 1.2 0.1 2.9 0.6 14.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.6 1.8 0.0 0.1 0.0 0.0 0.3 0.4 0.0 1.3 0.0 0.5 6.8 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 12.4 0.0 5.3 0.0 0.0 29.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 7.2 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.3 1.0 1.1 1.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 3.7 0.0 0.2 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.0 0.0 0.0 0.1 0.0 0.7 0.1 0.0 0.1 0.0 0.0 0.0 1.1 8.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.3 0.1 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.3 0.0 0.1 0.0 0.0 UMOD ENSG00000169344 Uromodulin P07911 16 20333051-20356301 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 693 "kidney: 2277.8" "Group enriched" "Detected in some" 146 "Collecting duct cells: 248.3;Distal tubular cells: 950.9" "Cancer enriched" "Detected in single" 39 "renal cancer: 5.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB009446, HPA043420, HPA054721" Enhanced "Secreted in other tissues" NA NA 55000000 66000000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 39: Non-specific - Basic cellular processes" "CAB009446: AB_2212378, HPA043420: AB_2678474, HPA054721: AB_2682585" "unprognostic (2.51e-2)" "unprognostic (1.33e-1)" "unprognostic (6.45e-2)" "unprognostic (3.02e-2)" "unprognostic (1.49e-2)" "unprognostic (1.43e-1)" 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2277.8 0.8 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 248.3 0.0 0.0 0.0 0.0 950.9 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UPB1 BUP1 ENSG00000100024 "Beta-ureidopropionase 1" Q9UBR1 22 24494107-24528390 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 216.0" "Group enriched" "Detected in many" 5 "Hepatocytes: 146.5;Proximal tubular cells: 68.5" "Cancer enriched" "Detected in some" 8 "liver cancer: 25.4" "Region enhanced" "Detected in single" "cerebral cortex: 1.8" "Group enriched" "Detected in some" 14 "basophil: 2.1;neutrophil: 2.1" "Lineage enriched" "Detected in single" 14 "granulocytes: 2.1" "Cell line enriched" "Detected in single" 7 "CACO-2: 3.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA000728, HPA076321" Enhanced NA NA 1400000 "Cluster 17: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA000728: AB_1080471, HPA076321: " "unprognostic (7.27e-2)" "unprognostic (4.57e-3)" "unprognostic (2.27e-1)" "unprognostic (7.62e-2)" "unprognostic (1.97e-1)" "unprognostic (1.09e-4)" "prognostic favorable (2.30e-7)" "unprognostic (8.41e-2)" "unprognostic (1.06e-1)" "unprognostic (2.93e-1)" "unprognostic (4.89e-6)" "unprognostic (3.82e-2)" "unprognostic (1.93e-2)" "unprognostic (1.81e-1)" "unprognostic (2.56e-1)" "unprognostic (1.99e-1)" "unprognostic (4.63e-3)" 0.2 0.2 0.2 0.2 0.6 2.0 0.1 0.7 1.8 0.2 0.2 0.2 1.2 0.2 0.2 0.1 0.3 0.1 1.9 0.2 0.0 25.7 216.0 0.8 0.2 0.1 0.1 0.2 0.1 0.0 0.4 0.0 0.4 0.3 0.1 1.1 0.1 0.1 0.5 0.9 0.4 0.1 0.0 0.8 0.2 3.0 0.4 0.6 0.1 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.4 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.2 0.6 0.7 1.8 0.2 0.0 0.1 0.1 0.4 0.0 0.4 0.1 0.8 0.0 2.0 0.3 0.6 0.6 1.3 0.1 0.0 4.0 0.3 0.3 2.4 4.3 0.0 1.8 10.4 0.1 0.1 0.0 11.7 0.1 1.2 0.2 0.6 1.9 2.4 5.3 0.7 0.4 0.1 1.4 0.0 0.5 0.0 0.6 3.6 146.5 0.1 0.0 1.2 0.0 0.0 5.1 2.7 1.4 0.3 1.0 0.0 0.0 21.3 0.4 0.0 0.0 0.3 0.0 0.1 0.0 0.7 1.2 0.0 68.5 0.0 1.8 0.0 2.7 3.7 12.8 6.8 0.0 1.1 0.3 0.9 0.2 0.1 1.1 UPP2 "UDRPASE2, UP2, UPASE2" ENSG00000007001 "Uridine phosphorylase 2" O95045 2 157876702-158136154 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "kidney: 45.8;liver: 23.9" "Cell type enhanced" "Detected in some" "Astrocytes: 24.2;Distal tubular cells: 13.7;Excitatory neurons: 32.5;Inhibitory neurons: 20.8;Oligodendrocyte precursor cells: 27.6;Proximal tubular cells: 82.1" "Cancer enriched" "Detected in some" 6 "liver cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA035225, HPA035226" Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Vesicles, Mitochondria" "HPA035225: AB_10604002, HPA035226: AB_10696503" "unprognostic (1.87e-1)" "unprognostic (2.33e-1)" "unprognostic (4.22e-3)" "unprognostic (1.36e-3)" "unprognostic (2.29e-1)" "unprognostic (1.55e-1)" "unprognostic (3.53e-2)" "unprognostic (5.51e-2)" "unprognostic (5.11e-2)" "unprognostic (1.23e-2)" "unprognostic (4.65e-3)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (4.89e-2)" "unprognostic (2.78e-2)" "unprognostic (1.78e-2)" "unprognostic (1.16e-2)" 0.0 0.1 3.3 0.0 2.9 0.0 0.0 1.8 3.0 0.1 1.4 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 3.7 1.9 45.8 23.9 0.0 0.1 1.3 1.3 0.3 0.1 0.0 0.2 0.0 1.1 0.0 0.0 0.9 0.4 0.0 0.0 0.3 0.1 0.0 1.4 0.0 0.0 0.1 1.6 0.0 0.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 2.9 1.8 3.0 3.7 1.9 1.3 1.3 1.1 1.4 1.6 2.4 0.0 0.0 0.0 24.2 0.2 0.0 0.1 0.0 0.0 1.3 0.1 0.3 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 13.7 0.0 0.1 0.2 0.1 0.1 0.0 0.0 32.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.1 8.2 0.0 0.0 20.8 0.0 0.0 0.9 0.0 0.1 0.3 0.5 0.0 2.8 0.0 0.1 0.0 27.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 82.1 0.0 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 USH1C "AIE-75, DFNB18, harmonin, NY-CO-37, NY-CO-38, PDZ-73, PDZ73, PDZD7C" ENSG00000006611 "USH1 protein network component harmonin" Q9Y6N9 11 17493895-17544416 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Hearing" "Cancer-related genes, Deafness, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 97.8;kidney: 54.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 190.0;Muller glia cells: 163.6;Paneth cells: 203.0;Proximal enterocytes: 430.7;Proximal tubular cells: 190.3;Undifferentiated cells: 115.7" "Group enriched" "Detected in many" 7 "colorectal cancer: 34.5;pancreatic cancer: 18.8;renal cancer: 29.4;stomach cancer: 15.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CACO-2: 60.6;HeLa: 21.8;OE19: 57.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB013690, HPA027398, HPA027492, HPA028033" Enhanced Enhanced Cytosol No NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol "CAB013690: , HPA027398: AB_10601775, HPA027492: AB_10601898, HPA028033: AB_10601782" "unprognostic (3.60e-2)" "unprognostic (6.19e-2)" "unprognostic (2.36e-1)" "unprognostic (3.83e-2)" "unprognostic (1.98e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (2.22e-1)" "unprognostic (2.78e-1)" "unprognostic (1.51e-2)" "unprognostic (9.65e-2)" "prognostic favorable (9.41e-4)" "unprognostic (1.29e-2)" "unprognostic (1.88e-1)" "unprognostic (1.62e-1)" "unprognostic (2.61e-1)" 0.4 0.3 2.8 5.9 6.8 0.0 0.2 2.8 3.9 0.1 1.5 51.5 97.8 0.1 0.3 0.0 2.9 25.9 0.1 9.0 4.7 54.0 0.6 0.1 0.1 6.1 5.7 0.0 3.9 0.0 6.7 0.0 7.0 0.0 48.3 19.0 0.0 0.3 0.0 0.0 96.5 2.1 4.1 0.0 26.7 0.2 5.9 0.1 1.1 0.0 0.0 0.6 0.1 8.3 0.0 1.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 60.6 8.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 21.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 57.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 6.8 2.8 3.9 9.0 4.7 6.1 5.7 7.0 4.1 5.9 8.3 0.0 0.0 0.0 18.3 1.6 0.0 0.1 0.0 0.0 0.7 0.0 1.3 0.6 52.9 0.7 5.5 2.1 0.0 0.0 190.0 21.5 20.5 1.0 1.7 0.0 0.4 64.0 0.0 0.6 27.5 0.0 0.3 53.5 0.0 4.5 0.0 0.0 0.0 0.0 1.7 0.2 92.9 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 163.6 0.0 0.5 36.4 56.0 203.0 0.0 0.2 0.0 430.7 190.3 1.0 4.9 0.0 0.0 0.1 0.1 1.3 0.0 0.0 0.0 0.8 0.1 115.7 0.1 VIL1 "D2S1471, VIL" ENSG00000127831 "Villin 1" P09327 2 218419121-218453295 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Actin capping, Actin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "intestine: 436.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 243.8;Enteroendocrine cells: 113.6;Intestinal goblet cells: 143.6;Paneth cells: 216.2;Proximal enterocytes: 558.5;Undifferentiated cells: 161.8" "Group enriched" "Detected in many" 4 "colorectal cancer: 56.4;stomach cancer: 23.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.3" "Group enriched" "Detected in some" 97 "CACO-2: 762.5;Hep G2: 365.3;OE19: 321.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002452, HPA006884, HPA006885" Enhanced Enhanced "Plasma membrane" NA NA 6800 "Cluster 9: Neutrophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "CAB002452: AB_564052, HPA006884: AB_1080566, HPA006885: AB_1080564" "unprognostic (1.28e-1)" "unprognostic (1.91e-2)" "unprognostic (1.61e-2)" "unprognostic (1.09e-1)" "unprognostic (1.83e-1)" "unprognostic (3.36e-1)" "unprognostic (3.03e-1)" "unprognostic (5.90e-2)" "unprognostic (2.44e-2)" "unprognostic (7.06e-2)" "unprognostic (4.14e-1)" "unprognostic (1.03e-1)" "unprognostic (2.25e-3)" "unprognostic (3.90e-1)" "unprognostic (2.58e-1)" "unprognostic (4.79e-2)" "unprognostic (4.65e-2)" 0.6 1.1 0.0 10.3 0.1 0.3 0.8 0.3 0.2 0.7 0.0 175.9 395.0 0.5 0.0 0.9 0.7 28.1 1.0 0.0 0.0 25.9 31.4 0.7 0.3 0.0 0.0 1.1 29.4 0.0 1.4 0.3 0.0 1.0 184.0 0.0 0.6 0.4 0.4 1.1 436.3 8.1 0.0 1.2 6.9 2.0 0.0 0.0 0.6 0.0 0.0 0.8 0.9 0.1 0.0 1.5 0.0 0.1 0.0 0.1 1.0 0.0 0.0 0.0 0.0 762.5 0.5 0.1 5.0 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.4 0.0 0.3 365.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.1 0.0 0.1 0.0 1.7 0.8 321.9 0.0 0.0 0.0 1.4 0.0 0.2 0.3 0.7 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.0 4.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 1.3 0.8 0.4 0.1 0.0 1.8 0.3 0.6 0.5 24.3 0.1 0.0 2.1 0.3 0.8 243.8 3.9 12.3 1.9 1.3 0.9 0.4 113.6 3.2 0.7 42.9 0.2 0.8 6.6 1.6 8.9 0.3 0.7 32.6 0.1 1.7 0.5 143.6 0.0 2.2 1.5 0.5 0.0 5.1 0.0 0.0 0.2 0.5 0.0 0.0 0.3 10.9 216.2 0.0 0.3 0.9 558.5 35.1 0.0 1.2 0.0 1.7 0.7 0.8 0.8 0.6 0.9 0.3 1.5 0.0 161.8 0.3 VSIG4 "CRIg, Z39IG" ENSG00000155659 "V-set and immunoglobulin domain containing 4" Q9Y279 X 66021738-66040125 "Plasma proteins, Predicted membrane proteins" "Complement alternate pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 166.0" "Group enriched" "Detected in many" 5 "Hofbauer cells: 989.8;Kupffer cells: 590.9;Macrophages: 328.4" "Cancer enriched" "Detected in all" 5 "glioma: 88.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "classical monocyte: 18.7;intermediate monocyte: 11.1;myeloid DC: 17.8" "Group enriched" "Detected in many" 31 "dendritic cells: 17.8;monocytes: 18.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003903, CAB026000" Enhanced Uncertain "Nucleoli,Plasma membrane,Cytosol" NA NA 59000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" Nucleoli "CAB026000: , HPA003903: AB_1858776" "unprognostic (6.87e-3)" "unprognostic (4.79e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (3.19e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-2)" "unprognostic (9.37e-3)" "unprognostic (1.24e-1)" "unprognostic (3.10e-1)" "unprognostic (1.37e-3)" "unprognostic (1.06e-1)" "unprognostic (2.77e-1)" "prognostic unfavorable (1.95e-6)" "unprognostic (3.70e-2)" "unprognostic (5.45e-2)" "unprognostic (3.37e-2)" "unprognostic (3.47e-2)" 137.1 68.8 17.9 44.2 18.8 7.8 44.2 17.0 36.6 14.1 21.5 40.9 22.5 15.5 5.3 15.4 66.8 39.6 30.0 18.2 18.3 17.9 51.0 166.0 27.8 25.1 23.6 12.9 14.3 6.8 7.0 139.6 25.8 10.6 31.7 2.2 24.5 9.3 8.2 10.8 43.9 108.3 18.9 69.3 22.9 7.3 37.6 5.4 12.3 12.5 1.8 61.5 11.6 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 18.7 0.1 0.0 11.1 0.0 0.0 0.0 0.2 17.8 0.1 0.0 0.0 0.5 0.0 0.4 0.1 0.0 5.6 17.9 18.8 17.0 36.6 18.2 18.3 25.1 23.6 25.8 18.9 37.6 26.7 1.3 3.2 16.1 0.0 1.2 2.3 0.3 0.0 0.0 0.0 2.6 0.5 1.8 7.2 3.1 0.0 0.0 5.3 0.3 0.0 0.0 0.1 7.9 0.0 0.0 10.4 0.0 0.0 0.0 0.0 4.9 2.7 0.0 0.0 3.8 0.0 5.0 3.2 989.8 0.0 0.0 0.0 0.0 590.9 111.8 16.6 1.5 328.4 3.6 12.2 1.5 0.5 0.0 0.5 0.0 0.0 0.1 0.4 0.3 0.3 0.0 0.1 4.4 0.0 6.6 0.6 2.0 0.3 0.9 0.5 1.7 12.3 1.5 0.0 0.0 0.2 VSIG8 ENSG00000243284 "V-set and immunoglobulin domain containing 8" P0DPA2 1 159854316-159862657 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 25.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 11.2;Collecting duct cells: 5.5;Gastric mucus-secreting cells: 5.1;Suprabasal keratinocytes: 4.5" "Cancer enhanced" "Detected in some" "head and neck cancer: 4.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA023219 Uncertain NA NA 650000 "Cluster 61: Skin - Cornification" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA023219: AB_1845635" "unprognostic (8.66e-3)" "unprognostic (2.17e-1)" "unprognostic (2.74e-1)" "unprognostic (9.13e-3)" "unprognostic (4.50e-3)" "unprognostic (1.15e-2)" "unprognostic (9.26e-2)" "unprognostic (6.28e-2)" "unprognostic (1.68e-2)" "unprognostic (2.79e-1)" "unprognostic (2.93e-3)" "unprognostic (9.32e-2)" "unprognostic (7.94e-7)" "unprognostic (1.72e-2)" "unprognostic (4.25e-1)" "unprognostic (1.81e-3)" "unprognostic (1.99e-1)" 0.6 0.1 0.5 0.1 0.5 0.0 0.1 2.0 0.3 3.4 1.8 0.1 0.1 0.1 0.0 4.0 1.3 0.1 0.2 0.2 0.0 5.5 0.0 0.5 0.1 1.4 0.8 0.8 0.1 0.0 0.2 0.1 1.4 0.1 0.0 0.0 5.5 0.0 0.1 25.6 0.1 0.0 0.6 0.2 0.1 0.4 0.1 0.4 0.2 0.0 6.5 0.1 3.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.5 2.0 0.3 0.2 0.0 1.4 0.8 1.4 0.6 0.1 0.4 0.5 0.0 0.0 0.0 0.1 11.2 0.7 0.2 1.2 2.6 0.5 0.4 0.2 1.5 0.3 5.5 0.0 0.2 0.6 0.6 0.0 0.1 0.6 1.7 0.8 0.5 3.6 0.0 0.0 0.0 0.2 0.9 5.1 0.9 0.0 2.3 0.4 0.0 0.2 0.0 0.0 2.5 0.0 0.0 0.9 0.2 0.6 0.4 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.1 0.1 0.0 1.4 0.8 2.1 0.1 2.2 0.4 0.0 0.9 0.6 0.5 0.0 1.8 4.5 0.1 1.1 1.1 1.1 0.8 WDR72 FLJ38736 ENSG00000166415 "WD repeat domain 72" Q3MJ13 15 53513741-53762878 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Biomineralization "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 105.7;liver: 33.1;thyroid gland: 57.9" "Cell type enhanced" "Detected in some" "Cholangiocytes: 12.8;Collecting duct cells: 22.0;Glandular and luminal cells: 13.2;Hepatocytes: 44.3;Proximal tubular cells: 93.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 9.9;OE19: 18.3;RPMI-8226: 17.5;RPTEC TERT1: 10.1;SuSa: 15.2;U-266/70: 7.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048212, HPA057410, HPA059819" Uncertain Approved Vesicles NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA048212: AB_2680315, HPA057410: AB_2683430, HPA059819: AB_2684133" "unprognostic (6.39e-4)" "unprognostic (1.41e-1)" "unprognostic (3.19e-2)" "unprognostic (1.79e-2)" "unprognostic (2.63e-2)" "unprognostic (3.37e-2)" "unprognostic (5.54e-2)" "unprognostic (2.20e-1)" "unprognostic (1.13e-1)" "unprognostic (1.26e-1)" "unprognostic (2.78e-2)" "unprognostic (1.09e-2)" "prognostic favorable (3.33e-16)" "unprognostic (2.83e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.80e-4)" "unprognostic (7.67e-2)" 0.1 0.0 0.1 0.2 0.1 0.0 0.8 0.0 0.1 7.2 0.0 0.6 2.6 1.4 0.5 0.4 2.6 3.9 0.1 0.0 0.1 105.7 33.1 0.8 0.1 0.1 0.4 0.2 3.5 1.8 0.3 0.1 0.1 0.1 0.8 0.7 18.4 0.6 0.0 2.0 0.9 0.0 0.0 0.1 1.1 0.5 0.1 0.0 57.9 0.0 0.0 1.7 0.0 0.3 0.0 9.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 3.2 0.1 6.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 3.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.9 18.3 0.1 0.0 0.1 17.5 10.1 3.5 1.9 0.0 0.0 0.1 0.0 15.2 2.4 0.0 0.1 0.3 0.5 0.0 0.1 7.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.4 0.1 0.0 0.1 0.3 0.1 6.4 3.6 0.0 0.5 0.1 1.1 0.0 0.6 0.5 0.0 0.1 0.6 12.8 0.0 22.0 0.0 0.6 0.0 0.2 9.8 3.2 1.2 4.9 1.0 0.1 0.0 0.0 0.4 0.5 2.1 0.2 0.0 13.2 0.0 0.0 0.0 44.3 0.1 3.3 0.5 0.0 0.0 0.6 0.0 0.3 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 93.2 0.1 0.1 0.0 0.0 0.1 1.0 1.6 0.9 0.4 0.1 0.7 0.0 0.3 6.4 WIPF3 "CR16, FLJ36931" ENSG00000122574 "WAS/WASL interacting protein family member 3" A6NGB9 7 29806486-29917066 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.9;ovary: 41.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 45.1;Granulosa cells: 149.4;Leydig cells: 50.7;Peritubular cells: 100.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 22.1;cerebral cortex: 49.9;hippocampal formation: 40.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 18.1;HEK 293: 4.1;K-562: 6.6;NTERA-2: 5.1;RPMI-8226: 11.3;SK-MEL-30: 4.5" "Region enhanced" "Detected in all" "hippocampal formation: 213.9" "Region enhanced" "Detected in all" "hippocampal formation: 156.3" "HPA041145, HPA041211" Uncertain Uncertain Mitochondria NA NA "Cluster 42: Non-specific - Transcription" "Cluster 47: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA041145: AB_10795001, HPA041211: AB_10795003" "prognostic favorable (7.93e-4)" "unprognostic (1.35e-1)" "unprognostic (1.37e-3)" "unprognostic (2.12e-3)" "unprognostic (3.65e-3)" "unprognostic (1.53e-1)" "unprognostic (8.95e-3)" "unprognostic (4.53e-2)" "unprognostic (3.49e-1)" "unprognostic (1.19e-2)" "unprognostic (1.08e-2)" "unprognostic (7.49e-2)" "unprognostic (1.61e-2)" "unprognostic (1.35e-1)" "unprognostic (2.27e-2)" "unprognostic (3.33e-2)" "unprognostic (1.41e-1)" 1.0 5.6 8.7 1.0 22.1 0.5 1.1 0.0 49.9 0.4 0.0 0.7 2.9 3.3 19.7 1.2 8.8 1.4 4.0 40.3 4.2 2.5 0.5 0.5 0.7 0.4 2.6 41.7 1.7 1.2 0.9 0.2 0.1 4.4 0.5 3.8 4.0 4.8 25.0 0.9 2.6 4.1 0.5 1.0 5.9 18.8 7.4 0.4 2.0 8.8 0.7 1.4 0.2 8.1 0.3 1.1 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.9 0.0 0.2 0.0 18.1 0.0 0.0 0.0 4.1 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 6.6 0.1 0.0 0.1 0.0 0.0 5.1 0.0 3.6 0.0 0.0 11.3 0.0 0.0 1.8 1.5 0.1 0.1 4.5 2.4 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.2 0.3 0.1 0.0 8.7 22.1 0.0 49.9 40.3 4.2 0.4 2.6 0.1 0.5 7.4 8.1 1.5 0.0 0.0 6.2 0.0 2.2 1.5 0.6 1.2 8.2 4.9 4.6 9.3 0.0 1.4 3.7 2.1 0.0 0.3 0.5 3.9 3.8 1.8 5.0 0.4 4.1 1.8 3.0 45.1 3.5 0.1 7.3 11.7 1.2 0.0 149.4 0.4 0.5 4.5 5.0 27.0 0.7 0.0 0.0 1.0 4.8 50.7 1.0 5.4 1.9 0.0 6.2 0.0 2.0 1.9 2.4 1.5 100.4 0.1 1.1 5.5 5.5 5.1 2.9 6.6 7.2 16.0 4.4 9.9 0.9 0.4 0.0 1.0 8.7 2.0 0.4 WT1 "AWT1, GUD, NPHS4, WAGR, WIT-2" ENSG00000184937 "WT1 transcription factor" P19544 11 32387775-32435564 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 67.6;fallopian tube: 52.3;ovary: 45.8" "Cell type enhanced" "Detected in some" "Collecting duct cells: 20.2;Endometrial stromal cells: 70.1;Endothelial cells: 16.3;Granulosa cells: 9.3;Late spermatids: 9.3" "Cancer enriched" "Detected in many" 14 "ovarian cancer: 55.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 20.7;HMC-1: 29.9;K-562: 19.6;NB-4: 37.2;THP-1: 19.6" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000327, HPA035717, HPA053848" Enhanced Enhanced Nucleoplasm NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "CAB000327: AB_2304486, HPA035717: AB_2674748, HPA053848: AB_2682279" "unprognostic (3.09e-3)" "unprognostic (9.97e-4)" "unprognostic (3.32e-1)" "unprognostic (8.24e-3)" "unprognostic (5.20e-2)" "unprognostic (1.98e-3)" "unprognostic (2.94e-2)" "unprognostic (1.59e-2)" "unprognostic (1.23e-2)" "unprognostic (4.15e-2)" "unprognostic (1.86e-2)" "unprognostic (1.36e-1)" "unprognostic (1.31e-10)" "unprognostic (2.65e-3)" "unprognostic (1.87e-1)" "unprognostic (1.96e-3)" "unprognostic (1.30e-2)" 26.5 0.2 0.0 0.5 0.1 0.0 0.1 0.0 0.1 18.4 0.0 0.7 0.0 67.6 5.3 0.0 52.3 1.3 4.5 0.1 0.0 16.3 0.1 0.8 0.0 0.2 0.1 45.8 0.1 0.0 0.0 1.3 0.0 0.7 0.0 0.0 0.0 2.9 0.0 0.0 0.1 33.1 0.0 19.0 0.2 24.2 0.0 0.0 0.0 0.0 0.0 0.2 8.4 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.1 0.0 0.0 0.0 8.1 0.0 0.0 0.0 8.4 20.7 0.0 1.2 4.7 10.8 29.9 0.0 0.0 3.4 0.0 0.0 0.0 0.7 19.6 0.0 2.0 0.0 11.2 37.2 0.8 0.0 6.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 2.1 19.6 0.2 0.0 3.3 0.0 0.3 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 20.2 0.0 1.0 0.0 0.0 0.0 0.0 3.6 2.2 70.1 16.3 0.0 0.0 0.1 0.0 0.5 7.3 0.0 1.4 0.0 9.3 1.4 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 9.3 8.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.1 0.0 2.3 0.0 0.0 6.6 0.0 2.0 4.5 1.0 0.0 0.0 0.8 0.5 0.4 0.0 0.1 XPNPEP2 ENSG00000122121 "X-prolyl aminopeptidase 2" O43895 X 129738949-129769536 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 166.6;kidney: 156.0" "Cell type enriched" "Detected in some" 6 "Proximal enterocytes: 475.9" "Cancer enhanced" "Detected in many" "liver cancer: 18.3" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 4.3;intermediate monocyte: 1.4;MAIT T-cell: 1.2;memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.8;naive CD8 T-cell: 2.0;non-classical monocyte: 2.8;T-reg: 1.4" "Group enriched" "Detected in many" 7 "monocytes: 2.8;T-cells: 4.3" "Cell line enhanced" "Detected in some" "ASC diff: 8.2;ASC TERT1: 40.1;HSkMC: 21.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA000339, CAB025136, CAB025269, HPA064568" Enhanced Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 13000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "CAB025136: , CAB025269: , HPA000339: AB_1858894, HPA064568: " "unprognostic (7.95e-2)" "unprognostic (5.73e-2)" "unprognostic (2.56e-1)" "unprognostic (6.21e-3)" "unprognostic (3.54e-2)" "unprognostic (1.54e-1)" "unprognostic (4.04e-1)" "unprognostic (3.26e-1)" "unprognostic (3.01e-1)" "unprognostic (2.41e-2)" "unprognostic (3.07e-1)" "unprognostic (9.28e-3)" "unprognostic (2.77e-2)" "unprognostic (6.53e-2)" "unprognostic (3.18e-2)" "unprognostic (1.39e-2)" "unprognostic (3.26e-3)" 7.5 0.9 0.1 3.7 0.1 0.2 3.0 0.1 0.1 3.7 0.1 5.5 99.0 2.4 0.1 2.2 6.3 4.3 5.3 0.1 0.1 156.0 23.1 2.1 0.5 0.2 0.1 1.8 0.3 0.3 0.1 1.2 0.1 1.8 6.3 0.0 1.5 0.4 0.5 4.4 166.6 6.0 0.1 0.3 3.4 0.1 0.1 1.0 1.4 2.4 0.4 7.8 4.0 0.1 0.0 0.0 0.5 0.0 8.2 40.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 0.0 0.0 21.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 4.3 1.4 1.2 0.0 1.3 2.8 0.2 0.2 0.4 2.0 0.1 0.0 2.8 0.4 1.4 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 1.2 0.0 0.0 0.0 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.8 0.0 0.2 0.5 11.4 5.9 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.2 0.0 0.0 10.0 1.1 0.0 0.0 0.0 0.4 18.5 0.8 0.0 0.3 12.8 0.0 1.0 3.6 0.0 0.0 1.0 1.8 1.0 0.0 0.0 3.1 0.0 0.1 0.0 21.0 0.0 0.1 0.0 475.9 75.1 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 1.0 1.2 0.9 0.0 8.4 0.0 XYLB "FLJ10343, FLJ12539" ENSG00000093217 Xylulokinase O75191 3 38346760-38421348 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Xylose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 33.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 39.3;Hepatocytes: 49.3;Inhibitory neurons: 35.9;Proximal tubular cells: 31.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 5.4" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA037863, HPA038415" Uncertain Approved "Nuclear speckles" NA NA 12000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA037863: AB_10672729, HPA038415: AB_10672592" "unprognostic (2.48e-1)" "unprognostic (9.72e-2)" "unprognostic (3.42e-2)" "unprognostic (6.25e-2)" "unprognostic (7.52e-2)" "unprognostic (5.19e-2)" "unprognostic (5.82e-2)" "unprognostic (1.26e-3)" "unprognostic (6.55e-2)" "unprognostic (2.22e-1)" "unprognostic (6.91e-3)" "unprognostic (4.63e-2)" "prognostic favorable (8.57e-4)" "unprognostic (3.26e-1)" "unprognostic (2.06e-1)" "unprognostic (5.78e-2)" "unprognostic (3.37e-2)" 1.4 2.3 1.3 1.5 1.0 2.2 3.0 5.4 2.0 1.6 0.0 4.1 5.8 1.9 0.8 1.9 1.1 1.6 0.5 0.9 0.7 11.4 33.4 0.7 1.0 0.9 0.2 2.2 2.5 1.1 0.8 0.9 1.1 1.6 4.6 2.1 5.3 0.9 0.6 1.5 6.4 1.4 0.0 1.0 3.5 1.0 0.9 1.6 0.7 0.5 0.8 1.2 1.3 0.6 3.5 6.4 2.8 6.7 4.2 4.3 6.3 5.9 2.0 4.5 4.4 8.2 3.6 3.7 1.4 7.6 5.4 2.5 8.1 2.5 5.6 5.0 6.2 7.5 5.0 24.1 2.2 10.1 7.7 3.0 5.2 5.8 2.7 1.9 4.7 8.5 18.0 6.2 5.0 2.4 8.3 1.4 3.8 8.9 7.9 4.2 5.5 5.0 0.6 6.3 3.6 3.2 3.7 16.0 12.7 2.4 7.2 6.1 2.6 9.0 7.3 15.6 2.5 3.5 6.6 8.5 5.4 9.1 7.2 1.4 0.9 2.0 0.6 1.6 0.5 0.2 0.5 0.3 1.7 0.3 0.6 0.6 1.9 0.5 1.4 0.6 1.5 0.4 1.3 1.0 5.4 2.0 0.9 0.7 0.9 0.2 1.1 0.0 0.9 0.6 1.0 0.0 1.3 14.0 0.9 0.9 2.1 1.8 6.8 3.2 3.0 3.4 1.1 2.8 1.5 0.0 0.0 4.3 1.7 3.8 1.9 1.0 0.5 0.4 3.5 1.8 0.0 3.4 39.3 3.0 3.8 2.3 8.6 1.0 0.0 1.3 1.1 49.3 4.0 0.0 35.9 5.7 2.0 1.0 3.7 1.0 1.5 2.0 0.0 17.8 1.0 0.4 0.0 17.1 17.7 1.3 5.8 1.9 1.6 1.7 13.0 31.7 1.3 5.1 0.0 2.4 1.4 0.5 2.7 4.1 0.9 1.4 0.8 1.8 5.1 2.1 ZNF804A C2orf10 ENSG00000170396 "Zinc finger protein 804A" Q7Z570 2 184598529-184939492 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 5.0;retina: 3.8" "Group enriched" "Detected in many" 9 "Excitatory neurons: 267.9;Inhibitory neurons: 676.0;Oligodendrocyte precursor cells: 186.5" "Cancer enhanced" "Detected in single" "glioma: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 28.3;RH-30: 17.7;THP-1: 13.9;U-698: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029195 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 6: Brain - Smell perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA029195: AB_10603011" "unprognostic (1.10e-1)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "unprognostic (2.05e-2)" "unprognostic (1.08e-2)" "unprognostic (1.26e-2)" "unprognostic (1.50e-1)" "unprognostic (2.41e-1)" "unprognostic (4.45e-1)" "unprognostic (2.38e-2)" "unprognostic (2.83e-2)" "unprognostic (5.20e-2)" "unprognostic (4.98e-4)" "unprognostic (6.21e-2)" "unprognostic (4.04e-1)" "unprognostic (8.45e-2)" "unprognostic (4.93e-2)" 0.0 0.2 1.6 1.0 4.7 0.6 0.0 4.7 5.0 0.1 0.0 0.2 0.5 0.0 0.0 0.1 0.0 1.1 0.0 3.3 3.5 0.6 0.1 0.3 0.9 2.1 0.8 0.2 0.0 0.0 0.0 0.1 1.6 1.2 0.3 3.8 0.1 1.3 0.0 0.0 1.2 0.1 0.5 0.6 0.4 0.2 1.8 0.0 1.4 0.0 1.0 0.4 0.0 0.6 0.0 0.0 1.5 0.0 0.0 0.0 0.0 2.9 6.3 2.1 1.9 0.0 0.0 28.3 0.0 0.0 2.6 0.0 0.4 0.0 4.6 0.2 0.0 7.4 1.0 0.1 10.0 7.1 0.0 3.1 0.0 0.0 1.6 3.2 4.9 0.0 0.0 1.2 0.0 0.0 0.0 6.8 0.0 0.0 4.8 0.0 17.7 1.1 0.0 0.0 0.4 3.1 0.0 0.0 0.0 0.1 0.0 13.9 0.0 6.8 0.1 0.2 2.8 3.1 0.0 20.5 7.7 2.0 2.2 0.0 0.2 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.6 4.7 4.7 5.0 3.3 3.5 2.1 0.8 1.6 0.5 1.8 0.6 0.1 0.0 0.6 13.4 9.2 0.0 0.0 0.0 0.0 38.0 0.1 0.1 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.2 2.2 0.6 0.0 5.5 267.9 0.0 0.0 2.2 0.0 0.3 0.0 0.9 0.0 0.2 2.9 3.3 676.0 1.1 0.0 1.6 3.7 0.6 0.3 5.4 0.0 6.5 3.5 1.0 0.0 186.5 5.4 0.0 0.0 0.0 21.5 0.0 1.5 0.1 0.0 2.9 6.6 0.1 0.7 5.3 1.2 0.0 0.0 0.0 0.5 1.1 2.7 0.1 ZYG11A ZYG11 ENSG00000203995 "Zyg-11 family member A, cell cycle regulator" Q6WRX3 1 52842511-52894998 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 2.9;testis: 3.8;thyroid gland: 2.3" "Cell type enhanced" "Detected in some" "Prostatic glandular cells: 2.5;Spermatocytes: 3.5;Spermatogonia: 7.9" "Cancer enriched" "Detected in many" 7 "testis cancer: 11.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 12.5;hTEC/SVTERT24-B: 10.4;K-562: 10.7;SiHa: 10.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030378, HPA030379" Uncertain Approved Nucleoplasm NA NA "Cluster 11: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 20: HeLa - Mitochondria" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "HPA030378: AB_10604159, HPA030379: AB_2673451" "unprognostic (7.94e-2)" "unprognostic (6.71e-3)" "unprognostic (1.04e-2)" "unprognostic (4.06e-3)" "unprognostic (1.59e-2)" "unprognostic (1.00e-4)" "unprognostic (1.87e-1)" "unprognostic (2.34e-1)" "unprognostic (4.56e-2)" "unprognostic (2.06e-2)" "unprognostic (4.01e-2)" "unprognostic (1.01e-1)" "unprognostic (6.15e-3)" "unprognostic (2.95e-1)" "unprognostic (1.21e-1)" "unprognostic (3.07e-1)" "unprognostic (1.02e-1)" 0.0 0.0 0.1 0.3 0.1 0.1 0.5 0.8 0.2 0.2 0.5 0.0 0.2 0.0 0.1 0.6 0.0 0.0 0.0 0.1 0.3 2.9 1.2 0.0 0.2 0.2 0.1 0.1 0.0 0.1 0.1 0.2 0.2 0.7 0.1 0.2 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 3.8 0.2 0.3 2.3 0.0 0.7 0.1 0.4 0.4 0.0 2.0 0.3 0.0 0.0 0.0 4.5 1.2 1.4 5.8 4.7 0.1 0.0 0.0 3.0 1.8 0.0 0.1 3.8 0.1 6.8 0.3 7.5 0.0 12.5 0.0 2.7 0.0 0.9 0.0 0.3 10.4 0.0 0.3 1.3 0.0 10.7 5.6 0.2 5.6 0.0 5.6 1.4 0.0 1.0 0.0 1.2 4.9 3.5 0.2 1.4 2.1 10.8 0.4 0.0 4.3 6.0 3.0 0.0 0.0 0.1 0.0 0.0 2.7 4.9 0.0 0.0 0.0 0.9 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.8 0.2 0.1 0.3 0.2 0.1 0.2 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.6 0.5 1.6 0.5 0.7 0.0 0.1 0.0 0.0 1.1 0.3 0.4 0.0 0.0 0.3 0.5 0.1 0.1 0.0 0.0 0.4 0.0 0.4 0.2 0.0 0.5 0.0 0.1 0.4 0.9 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.4 0.0 0.0 0.0 0.9 2.5 0.0 1.3 0.2 1.3 0.0 0.6 0.3 3.5 7.9 1.5 0.1 0.3 0.1 0.0 0.1 0.3