Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AATK "AATYK, AATYK1, KIAA0641, LMR1, LMTK1, PPP1R77" ENSG00000181409 "Apoptosis associated tyrosine kinase" Q6ZMQ8 17 81110487-81166221 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 184.7" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 243.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "neutrophil: 2.0" "Lineage enriched" "Detected in single" 11 "granulocytes: 2.0" "Group enriched" "Detected in some" 6 "CACO-2: 60.1;SH-SY5Y: 17.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009073 Enhanced Uncertain Mitochondria NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 70: Brain - Nervous system development" "Cluster 39: CACO-2 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA009073: AB_1078076" "unprognostic (3.47e-3)" "unprognostic (3.01e-2)" "unprognostic (1.12e-1)" "unprognostic (1.95e-4)" "unprognostic (1.96e-1)" "unprognostic (1.94e-1)" "unprognostic (7.29e-2)" "unprognostic (9.85e-2)" "unprognostic (6.09e-2)" "unprognostic (4.27e-2)" "unprognostic (2.88e-3)" "unprognostic (2.48e-1)" "unprognostic (4.28e-6)" "unprognostic (1.58e-3)" "unprognostic (1.21e-1)" "unprognostic (1.39e-1)" "unprognostic (4.57e-2)" 3.3 4.2 35.4 3.1 79.2 3.7 2.3 43.4 82.0 2.8 0.0 7.7 30.9 0.9 0.5 1.8 2.8 2.7 3.9 30.6 30.8 1.0 0.9 9.5 0.9 99.2 67.9 0.9 20.6 3.0 17.3 2.0 63.4 5.2 0.5 2.1 5.9 3.3 0.6 4.5 23.7 0.8 38.8 9.7 5.8 0.7 78.4 0.1 2.9 1.0 0.2 2.8 4.2 184.7 0.3 0.5 0.7 4.9 0.0 0.0 0.7 0.1 0.0 0.0 0.0 60.1 0.2 0.0 0.3 0.0 0.0 1.2 0.6 0.0 0.0 0.0 2.0 2.2 3.2 2.8 0.1 0.0 3.9 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 1.4 0.0 6.6 0.0 0.2 0.7 0.6 0.3 2.1 4.1 0.6 0.0 0.2 4.5 17.1 0.2 0.4 2.3 0.2 1.1 2.2 2.1 0.4 0.5 0.4 0.0 0.1 0.0 0.0 0.2 1.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.0 35.4 79.2 43.4 82.0 30.6 30.8 99.2 67.9 63.4 38.8 78.4 184.7 6.3 32.1 20.3 17.0 0.3 0.3 1.0 1.9 0.6 43.0 1.3 5.1 2.2 2.8 0.1 0.0 4.2 0.1 0.5 6.8 0.0 0.6 0.0 0.4 0.2 1.8 1.8 0.0 34.6 1.8 0.1 0.5 7.1 0.6 6.3 2.0 1.1 0.1 2.1 21.9 36.0 4.6 0.0 2.8 0.4 0.0 1.5 8.2 5.4 2.8 1.5 9.6 4.1 21.1 243.2 1.1 4.2 2.6 0.1 0.9 34.1 0.9 0.0 4.4 0.0 4.3 0.8 0.4 0.5 0.0 0.3 2.3 1.4 0.4 7.0 0.2 ABCG1 ABC8 ENSG00000160179 "ATP binding cassette subfamily G member 1" P45844 21 42199689-42297244 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 122.6;Syncytiotrophoblasts: 63.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 35.5;neutrophil: 36.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 36.6" "Cell line enhanced" "Detected in many" "hTCEpi: 25.5;JURKAT: 38.4;MCF7: 33.2;MOLT-4: 31.5;OE19: 54.9;RPMI-8226: 25.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031470, HPA031471" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus, Vesicles" "HPA031470: AB_10599188, HPA031471: AB_10600201" "unprognostic (2.89e-2)" "unprognostic (2.53e-2)" "unprognostic (9.96e-2)" "unprognostic (4.20e-3)" "unprognostic (2.87e-1)" "unprognostic (3.09e-2)" "unprognostic (5.74e-2)" "unprognostic (2.07e-1)" "unprognostic (1.54e-1)" "unprognostic (1.66e-3)" "unprognostic (3.66e-3)" "unprognostic (6.37e-2)" "prognostic favorable (7.16e-6)" "unprognostic (1.40e-2)" "unprognostic (2.00e-2)" "unprognostic (1.66e-1)" "unprognostic (2.42e-2)" 17.2 37.7 18.3 12.1 25.5 8.1 15.2 14.4 20.2 8.1 20.0 14.1 17.5 4.9 3.9 4.1 6.3 13.8 10.5 15.5 17.0 10.2 6.3 29.4 18.1 12.0 19.9 6.3 5.3 24.4 10.7 13.7 13.3 6.2 15.0 29.1 16.1 7.0 19.6 16.8 22.0 4.0 12.2 31.2 15.9 1.1 20.3 18.9 8.5 6.2 12.1 12.9 5.0 24.7 0.0 6.0 4.6 2.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 3.1 1.9 0.8 0.0 0.7 0.9 0.0 8.8 0.0 8.5 0.5 10.2 19.2 0.0 17.4 0.0 0.4 2.0 25.5 0.1 3.9 0.0 18.2 38.4 0.0 0.1 0.0 33.2 31.5 0.2 1.4 54.9 10.3 0.4 0.0 25.8 0.0 2.8 22.3 5.8 3.7 13.5 0.0 0.4 5.7 0.9 11.8 0.0 4.7 0.1 0.0 13.1 4.2 0.0 0.1 3.3 0.5 1.7 1.7 35.5 3.0 0.5 5.6 5.5 6.1 6.0 1.1 7.0 5.8 5.0 36.6 7.4 0.3 2.5 7.4 2.1 18.3 25.5 14.4 20.2 15.5 17.0 12.0 19.9 13.3 12.2 20.3 24.7 38.2 6.4 8.2 0.3 21.3 8.9 6.9 3.2 5.7 48.4 4.1 6.9 9.5 4.3 5.9 25.8 50.1 7.0 7.0 33.4 3.9 2.6 4.5 21.6 6.3 33.8 3.5 5.7 13.2 1.2 1.8 7.5 11.2 45.3 0.0 1.2 42.8 0.6 16.0 11.8 17.8 12.1 8.2 44.5 23.4 7.6 0.3 20.9 3.6 7.5 4.3 16.1 3.1 43.2 40.6 2.3 8.3 1.9 4.0 3.0 36.6 1.1 4.5 122.6 6.6 1.6 3.5 0.6 0.5 1.0 6.7 63.1 21.4 10.4 1.1 9.1 ABHD5 "CGI-58, NCIE2" ENSG00000011198 "Abhydrolase domain containing 5, lysophosphatidic acid acyltransferase" Q8WTS1 3 43690108-43734371 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Differentiation, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Cataract, Deafness, Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 205.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 67.8;neutrophil: 42.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 67.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020685, HPA035851, HPA035852" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Cytosol" Nucleoplasm "CAB020685: , HPA035851: AB_10671942, HPA035852: AB_10672073" "unprognostic (2.58e-1)" "unprognostic (2.73e-1)" "prognostic favorable (8.89e-4)" "unprognostic (1.07e-1)" "unprognostic (1.75e-2)" "unprognostic (2.26e-1)" "unprognostic (6.13e-2)" "unprognostic (2.40e-2)" "unprognostic (5.33e-2)" "unprognostic (3.50e-3)" "unprognostic (2.56e-2)" "unprognostic (4.13e-3)" "prognostic favorable (9.17e-5)" "unprognostic (2.48e-1)" "unprognostic (8.87e-2)" "unprognostic (4.18e-2)" "unprognostic (4.18e-2)" 38.8 12.5 6.7 8.5 8.6 39.6 27.9 10.5 8.9 9.8 6.0 12.3 9.9 5.7 4.1 31.1 5.1 11.6 13.4 6.8 7.4 12.0 21.7 16.4 3.4 9.2 8.2 4.6 16.0 12.2 5.6 10.2 9.1 7.1 7.5 6.3 27.4 8.4 15.0 38.0 10.5 9.3 9.3 9.4 12.1 10.8 8.4 6.8 15.5 18.5 7.9 16.7 16.9 11.9 18.9 6.8 8.2 9.7 32.0 12.8 17.1 77.4 27.1 18.8 14.9 9.4 6.4 16.2 10.9 23.2 15.8 5.8 16.5 18.5 22.6 58.4 13.2 36.6 24.4 7.5 15.7 9.2 13.2 13.0 64.6 31.3 28.5 18.8 33.3 10.8 23.9 14.2 46.9 11.0 7.6 6.9 22.8 16.7 20.4 3.1 24.1 8.6 27.9 40.4 10.6 13.6 36.9 20.5 9.8 9.8 18.9 8.9 19.3 18.1 13.6 35.0 34.5 11.1 34.0 7.7 20.3 17.3 16.0 67.8 14.7 9.5 2.3 7.9 1.7 3.5 1.7 2.7 6.8 4.0 1.6 2.5 42.5 2.0 5.7 1.9 4.8 5.3 6.7 8.6 10.5 8.9 6.8 7.4 9.2 8.2 9.1 9.3 8.4 11.9 117.5 25.6 51.8 12.7 44.8 39.9 27.5 25.9 88.8 11.9 149.9 116.2 10.3 14.3 49.6 27.6 27.1 16.7 80.3 65.0 33.2 57.5 19.5 47.5 49.0 34.6 36.2 69.0 24.1 61.5 24.9 53.7 67.8 114.0 16.5 8.8 18.2 12.7 18.0 3.3 24.1 23.7 34.6 44.1 17.4 17.1 5.3 79.8 7.2 11.2 35.9 11.0 12.3 18.1 28.8 75.2 49.8 5.7 41.8 25.5 98.5 39.8 19.1 17.4 0.0 32.0 46.4 47.3 41.9 111.7 40.9 205.4 42.6 15.2 21.9 71.6 ACER2 "ALKCDase2, ASAH3L, FLJ41587" ENSG00000177076 "Alkaline ceramidase 2" Q5QJU3 9 19409009-19452505 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "stomach 1: 61.8;urinary bladder: 39.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 19.7;Gastric mucus-secreting cells: 21.9;Inhibitory neurons: 10.3;Microglial cells: 26.2;Oligodendrocytes: 7.0" "Cancer enhanced" "Detected in many" "urothelial cancer: 15.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "BEWO: 29.7;RT4: 73.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 15: RT4 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.94e-1)" "unprognostic (2.29e-1)" "unprognostic (2.06e-1)" "unprognostic (2.30e-1)" "unprognostic (1.57e-1)" "unprognostic (1.69e-1)" "unprognostic (1.19e-1)" "unprognostic (3.95e-2)" "unprognostic (2.03e-1)" "unprognostic (3.90e-1)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (2.13e-2)" "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "unprognostic (7.42e-2)" "unprognostic (8.46e-3)" 6.9 1.4 4.5 1.1 3.4 0.6 5.0 2.7 5.0 1.7 2.0 3.3 4.5 1.4 4.2 2.2 3.7 1.7 2.9 4.4 3.1 1.9 2.4 2.2 1.0 3.2 3.1 1.0 6.8 2.5 1.1 9.7 4.3 3.7 4.3 3.8 1.9 4.5 1.2 5.9 2.7 1.3 2.8 1.4 61.8 1.9 5.9 2.4 2.5 1.0 1.3 39.2 1.7 3.7 1.2 2.0 3.9 2.0 6.2 0.5 29.7 2.1 1.4 0.7 1.0 0.6 1.9 1.3 0.7 0.3 0.4 4.5 0.8 5.8 1.5 2.4 1.1 2.1 1.6 3.0 1.3 0.5 2.0 1.8 5.6 2.2 2.4 0.6 6.2 2.1 3.1 3.8 2.0 1.7 3.6 1.8 3.1 11.1 0.9 3.2 1.0 0.7 0.6 73.6 6.9 1.8 0.4 2.2 0.5 9.3 2.7 2.5 3.1 0.5 1.5 0.6 0.9 1.4 1.7 1.4 0.6 1.5 1.3 0.0 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 4.5 3.4 2.7 5.0 4.4 3.1 3.2 3.1 4.3 2.8 5.9 3.7 3.2 0.0 0.0 1.0 0.7 0.3 0.4 0.1 0.6 1.0 0.3 0.4 0.1 0.0 0.1 0.0 2.1 0.5 0.4 0.0 0.0 0.1 2.6 0.3 0.2 0.8 0.0 0.8 19.7 0.0 0.6 0.3 21.9 0.4 0.0 0.0 1.4 0.0 0.1 0.0 10.3 0.0 0.0 0.0 0.0 4.0 0.3 0.2 0.0 26.2 0.0 0.6 0.0 5.5 7.0 0.1 0.0 0.0 0.4 0.2 0.0 0.1 0.1 0.6 0.0 0.6 0.4 0.4 0.4 0.8 0.0 4.0 0.3 0.0 0.0 1.1 ACSL5 "ACS2, ACS5, FACL5" ENSG00000197142 "Acyl-CoA synthetase long chain family member 5" Q9ULC5 10 112374018-112428380 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 217.8;intestine: 418.0;liver: 165.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 164.9;Endometrial ciliated cells: 159.9;Glandular and luminal cells: 292.3;Proximal enterocytes: 462.5" "Cancer enhanced" "Detected in all" "colorectal cancer: 87.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 138.8;RT4: 143.3;U-937: 70.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007162, CAB035986, CAB062546" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 9: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" Mitochondria Nucleoplasm "CAB035986: AB_941506, CAB062546: AB_2665614, HPA007162: AB_2667761" "unprognostic (5.75e-3)" "unprognostic (2.06e-1)" "unprognostic (3.08e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.45e-1)" "unprognostic (2.13e-2)" "unprognostic (4.92e-2)" "unprognostic (5.90e-2)" "unprognostic (1.67e-1)" "unprognostic (4.06e-2)" "unprognostic (4.18e-3)" "unprognostic (7.40e-2)" "unprognostic (5.25e-3)" "unprognostic (2.11e-1)" "unprognostic (1.10e-1)" "unprognostic (5.92e-3)" "unprognostic (1.08e-3)" 23.8 4.2 13.1 29.0 12.6 16.2 21.3 13.0 15.5 51.4 10.4 111.7 358.9 30.3 217.8 7.9 45.0 21.5 9.4 12.1 13.4 9.0 165.5 35.6 28.0 14.4 13.1 17.0 5.5 2.2 2.6 8.6 14.9 12.3 116.6 1.5 5.5 20.3 3.9 3.4 418.0 15.5 14.0 25.7 44.2 9.6 15.3 16.4 7.2 8.8 28.0 76.3 7.6 13.2 38.6 0.9 0.7 0.1 2.5 0.4 3.3 1.1 7.3 0.3 0.6 34.8 138.8 46.7 8.4 1.9 6.8 0.3 0.0 0.2 0.8 39.4 0.0 36.5 1.3 60.9 8.8 57.3 59.2 5.9 0.0 0.8 0.0 2.7 2.8 0.0 0.1 20.6 0.1 0.0 0.1 26.3 0.1 32.2 1.3 12.9 0.2 28.6 3.8 143.3 0.1 0.9 55.8 21.0 0.1 0.1 0.1 31.7 40.5 0.5 0.4 2.2 2.5 14.8 0.1 22.6 1.2 70.5 0.1 27.4 15.1 27.5 25.2 27.9 24.9 16.3 20.4 27.8 31.1 13.1 13.8 21.4 3.9 26.1 27.7 9.8 41.5 21.1 13.1 12.6 13.0 15.5 12.1 13.4 14.4 13.1 14.9 14.0 15.3 13.2 23.4 12.8 51.3 0.0 20.1 3.8 10.3 10.7 8.6 0.1 7.0 4.6 1.7 12.8 23.6 0.0 4.2 1.8 10.5 164.9 0.0 13.3 92.6 159.9 37.6 24.7 40.8 10.7 1.3 6.4 2.6 5.7 41.8 292.3 17.2 0.5 16.1 88.6 18.9 0.0 1.1 79.0 0.0 22.4 57.8 42.6 15.8 24.9 3.6 17.8 11.5 0.1 16.5 1.0 1.0 48.0 122.4 12.0 20.3 7.1 462.5 0.2 8.2 1.2 0.0 0.8 3.3 4.0 1.9 3.3 1.7 0.7 24.0 6.4 103.3 50.0 ACVRL1 "ACVRLK1, ALK1, HHT, HHT2, ORW2" ENSG00000139567 "Activin A receptor like type 1" P37023 12 51906908-51923361 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 96.3" "Cell type enhanced" "Detected in many" "Adipocytes: 107.3;Distal enterocytes: 182.7;Endothelial cells: 84.7;Fibroblasts: 56.0;Hepatic stellate cells: 60.3;Paneth cells: 74.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 19 "classical monocyte: 1.5;myeloid DC: 2.1" "Group enriched" "Detected in many" 19 "dendritic cells: 2.1;monocytes: 1.5" "Cell line enhanced" "Detected in some" "ASC diff: 61.4;ASC TERT1: 42.1;EFO-21: 61.0;HUVEC TERT2: 200.0;TIME: 161.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007041 Approved "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA007041: AB_1078097" "unprognostic (2.50e-1)" "unprognostic (4.83e-1)" "unprognostic (3.79e-2)" "unprognostic (3.61e-2)" "unprognostic (4.98e-1)" "unprognostic (4.06e-3)" "unprognostic (2.79e-1)" "unprognostic (1.35e-1)" "unprognostic (5.80e-2)" "unprognostic (5.10e-2)" "unprognostic (4.60e-2)" "unprognostic (4.64e-2)" "unprognostic (1.12e-3)" "unprognostic (1.39e-1)" "unprognostic (7.98e-3)" "unprognostic (2.79e-1)" "unprognostic (1.10e-1)" 49.2 12.1 17.1 20.1 14.5 0.6 38.4 15.5 14.9 35.9 10.5 39.2 10.2 28.1 4.3 11.4 32.7 14.3 38.5 13.3 14.6 29.8 3.3 96.3 15.1 17.8 16.7 4.8 12.0 23.6 6.2 83.8 18.7 17.7 28.4 0.7 11.8 13.3 18.2 18.5 28.5 16.2 14.0 29.2 19.1 1.7 22.0 4.6 29.2 15.7 6.1 25.1 25.6 15.0 0.0 0.7 0.4 0.0 61.4 42.1 0.1 3.0 5.6 0.1 0.3 0.3 0.4 0.1 61.0 24.0 0.2 0.0 0.0 0.0 0.1 0.1 2.1 1.4 0.0 0.0 9.0 0.0 1.3 16.8 0.1 0.4 0.0 0.0 200.0 0.0 0.2 0.1 1.1 0.5 0.0 0.6 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.9 0.0 0.0 0.1 0.4 0.0 4.1 161.2 0.0 0.4 0.7 0.0 0.0 0.1 0.2 0.3 0.9 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 17.1 14.5 15.5 14.9 13.3 14.6 17.8 16.7 18.7 14.0 22.0 15.0 107.3 3.2 7.9 0.0 0.6 5.2 0.3 0.0 0.6 0.4 1.0 1.3 4.0 0.0 1.3 0.0 0.0 0.6 0.3 182.7 0.0 4.0 0.0 1.4 19.9 84.7 5.4 0.0 0.1 1.4 36.9 56.0 0.5 0.7 0.0 0.0 60.3 0.1 12.0 0.0 0.0 26.4 0.0 30.9 12.4 1.2 11.8 7.8 5.4 25.3 9.9 2.0 0.0 1.0 0.1 0.0 74.7 3.4 0.1 0.6 4.5 0.0 2.8 0.4 39.5 32.9 18.2 0.1 0.8 0.6 5.4 2.6 1.2 0.6 49.3 1.0 ADCY4 AC4 ENSG00000129467 "Adenylate cyclase 4" Q8NFM4 14 24318349-24335093 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 90.9;Endothelial cells: 74.6;Hepatic stellate cells: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 2.9" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.9" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 2.9;TIME: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB005070, HPA048344" Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB005070: AB_2273639, HPA048344: AB_2680366" "unprognostic (5.59e-2)" "unprognostic (1.34e-1)" "unprognostic (3.47e-4)" "prognostic favorable (8.20e-4)" "unprognostic (4.06e-1)" "unprognostic (2.82e-3)" "unprognostic (1.75e-4)" "unprognostic (8.58e-2)" "unprognostic (2.51e-2)" "unprognostic (7.88e-2)" "unprognostic (6.77e-2)" "unprognostic (7.87e-2)" "prognostic unfavorable (7.01e-4)" "unprognostic (8.02e-2)" "unprognostic (3.88e-2)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" 18.0 2.6 2.8 2.3 2.2 0.0 16.1 2.2 2.8 9.2 2.0 3.9 0.9 8.8 0.5 3.7 8.2 2.9 16.9 2.0 2.1 10.2 1.4 9.9 1.6 2.7 2.5 2.4 2.3 1.0 1.7 9.9 2.6 5.3 0.7 0.0 3.7 1.4 4.3 4.7 4.5 1.9 2.4 9.9 3.7 1.1 3.0 0.4 7.7 2.8 0.8 5.9 6.7 2.3 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.3 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.1 0.1 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.8 2.2 2.2 2.8 2.0 2.1 2.7 2.5 2.6 2.4 3.0 2.3 90.9 0.0 1.8 0.3 1.0 3.6 0.4 0.3 3.4 0.0 1.5 1.5 10.6 0.0 0.9 1.8 0.0 0.2 1.6 2.9 0.0 1.2 1.3 0.5 1.1 74.6 1.2 0.4 0.2 3.1 0.1 4.7 7.1 0.6 1.3 0.0 50.3 0.2 1.4 1.7 0.2 7.9 0.0 5.0 3.1 6.9 0.0 1.5 7.2 12.2 2.5 0.9 1.0 0.0 0.0 2.1 3.8 0.0 1.4 0.4 2.4 0.0 1.1 0.2 6.6 1.7 5.7 0.3 0.8 0.6 2.8 0.0 1.6 0.5 2.1 0.2 AHRR "AHH, AHHR, bHLHe77, KIAA1234" ENSG00000063438 "Aryl-hydrocarbon receptor repressor" A9YTQ3 5 321759-438291 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "testis: 46.4" "Group enriched" "Detected in some" 10 "Early spermatids: 299.1;Late spermatids: 168.8;Spermatocytes: 123.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 59.6;HMC-1: 76.8;NB-4: 91.1;WM-115: 53.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA021483 Supported Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 24: NB-4 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA021483: AB_1855110" "unprognostic (2.06e-4)" "unprognostic (3.48e-2)" "unprognostic (8.71e-3)" "unprognostic (2.23e-1)" "unprognostic (1.09e-1)" "unprognostic (9.33e-4)" "unprognostic (4.08e-2)" "unprognostic (1.06e-1)" "unprognostic (1.17e-1)" "unprognostic (1.02e-5)" "unprognostic (1.87e-1)" "unprognostic (5.07e-2)" "unprognostic (1.65e-6)" "unprognostic (1.70e-1)" "unprognostic (1.94e-1)" "unprognostic (1.20e-1)" "unprognostic (3.55e-2)" 1.4 0.7 2.2 0.6 1.8 0.4 0.8 0.0 6.0 3.8 1.1 2.1 0.7 1.6 0.5 2.2 0.7 1.2 0.5 5.0 1.7 1.6 0.7 2.2 0.4 0.4 0.7 2.6 0.6 0.1 1.5 2.0 0.0 1.0 1.1 0.1 0.7 0.1 0.5 5.9 1.9 0.3 0.0 5.7 1.1 46.4 2.6 0.2 1.4 0.0 0.4 3.4 2.2 0.0 0.4 5.8 1.4 1.0 6.1 11.9 11.0 22.5 30.0 10.7 18.4 0.6 6.7 0.6 10.1 38.6 2.2 0.5 0.9 0.5 5.1 1.2 2.8 8.6 59.6 0.9 3.5 1.6 76.8 1.4 0.8 7.3 1.3 17.3 3.4 0.8 1.0 0.6 11.8 0.7 0.3 91.1 0.5 2.6 8.9 1.3 0.5 0.4 0.5 0.2 10.0 0.4 27.6 3.7 14.7 0.1 0.5 36.4 6.1 20.5 1.6 21.5 0.4 2.6 3.6 0.8 8.3 0.8 53.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 1.8 0.0 6.0 5.0 1.7 0.4 0.7 0.0 0.0 2.6 0.0 0.6 0.0 0.0 2.0 0.2 2.2 0.0 0.1 0.0 0.4 0.2 0.3 1.2 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.2 299.1 0.3 0.8 3.6 0.0 0.0 11.1 0.2 5.8 2.7 0.5 0.7 0.0 0.3 0.0 0.0 0.8 0.0 9.5 0.1 0.0 0.0 9.7 168.8 3.4 1.5 19.6 3.7 5.7 0.2 0.0 3.5 2.9 0.2 0.0 1.2 0.1 0.3 0.1 0.1 0.2 0.2 6.6 0.0 3.0 123.7 6.9 0.1 1.4 0.8 1.2 0.7 0.1 0.2 AP003108.2 ENSG00000256591 "Novel transcript" 11 61429220-61485822 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Collecting duct cells: 3.7;dendritic cells: 1.4;Endometrial stromal cells: 1.5;Glandular and luminal cells: 1.4;Granulosa cells: 3.4;Respiratory ciliated cells: 1.5;Theca cells: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 28.0" "Low region specificity" "Detected in all" HPA039732 Approved NA NA "Cluster 35: T-regs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "HPA039732: AB_10962868" "unprognostic (1.23e-1)" "unprognostic (8.61e-2)" "unprognostic (9.60e-2)" "unprognostic (4.91e-2)" "unprognostic (5.69e-2)" "unprognostic (5.98e-2)" "unprognostic (4.41e-2)" "unprognostic (6.40e-2)" "unprognostic (3.53e-2)" "unprognostic (5.83e-2)" "unprognostic (4.98e-1)" "unprognostic (2.28e-1)" "unprognostic (2.36e-7)" "unprognostic (5.74e-2)" "unprognostic (9.69e-2)" "unprognostic (1.40e-1)" "unprognostic (4.66e-3)" 5.1 4.7 2.7 4.0 3.1 8.7 4.0 3.0 3.9 5.9 2.6 2.7 2.2 3.6 3.1 3.4 3.2 4.8 7.0 3.1 3.4 3.6 2.4 3.8 4.6 3.2 3.3 2.1 2.0 2.3 1.3 3.1 3.3 3.3 3.3 1.0 2.6 2.7 1.8 1.7 2.6 4.2 3.0 4.4 3.4 2.9 3.2 7.7 5.1 5.9 4.8 5.4 1.9 3.1 6.8 3.3 3.8 6.1 9.7 8.1 2.0 8.9 7.6 6.6 6.2 2.6 4.5 7.1 14.5 8.3 5.5 3.0 4.5 6.3 3.9 6.3 5.3 5.4 0.9 0.9 11.4 4.2 2.0 15.6 3.8 9.8 7.8 4.2 16.7 9.2 5.8 6.0 10.9 5.3 14.1 4.0 8.5 5.8 4.5 8.4 5.8 8.6 4.4 5.4 3.0 3.8 3.7 3.5 12.6 2.5 4.9 4.8 28.0 8.4 4.7 4.5 5.0 2.2 9.5 4.8 7.2 5.5 6.3 5.9 8.0 8.4 11.6 7.3 14.6 5.9 11.5 11.8 6.3 6.8 13.2 12.3 11.2 7.4 6.8 6.8 12.9 10.2 2.7 3.1 3.0 3.9 3.1 3.4 3.2 3.3 3.3 3.0 3.2 3.1 0.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.0 0.0 0.6 3.7 0.0 0.3 1.4 0.0 0.0 0.2 0.0 0.7 1.5 0.6 0.0 0.0 0.0 0.2 0.4 0.3 0.0 1.4 1.3 3.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.6 1.5 0.0 0.0 AP1S2 "MRX59, MRXS5, PGS, SIGMA1B" ENSG00000182287 "Adaptor related protein complex 1 subunit sigma 2" P56377 X 15825806-15854931 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "epididymis: 663.3" "Cell type enhanced" "Detected in all" "Hofbauer cells: 259.8;Kupffer cells: 392.6;Langerhans cells: 609.2;Macrophages: 362.7;monocytes: 630.0" "Group enriched" "Detected in all" 4 "endometrial cancer: 13.1;glioma: 22.0;melanoma: 49.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 326.8;intermediate monocyte: 325.0;myeloid DC: 221.1;non-classical monocyte: 175.4;plasmacytoid DC: 82.2" "Group enriched" "Detected in all" 5 "dendritic cells: 221.1;monocytes: 326.8" "Cell line enhanced" "Detected in all" "Karpas-707: 298.0;SK-MEL-30: 442.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049894, HPA060945" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus, Vesicles" "HPA049894: AB_2680939, HPA060945: AB_2684393" "prognostic favorable (9.86e-4)" "unprognostic (4.62e-2)" "unprognostic (2.11e-1)" "unprognostic (1.68e-1)" "unprognostic (2.47e-3)" "unprognostic (3.85e-1)" "unprognostic (2.03e-3)" "unprognostic (5.76e-2)" "unprognostic (1.43e-2)" "prognostic favorable (5.53e-6)" "unprognostic (1.85e-2)" "unprognostic (5.61e-2)" "unprognostic (5.08e-2)" "unprognostic (6.35e-2)" "unprognostic (3.13e-1)" "unprognostic (9.34e-2)" "unprognostic (6.47e-2)" 28.3 21.4 24.6 36.7 28.4 38.3 15.0 32.0 36.9 31.6 27.3 42.1 11.9 52.2 663.3 21.4 13.5 20.1 74.8 25.1 48.0 13.1 15.9 25.8 33.2 42.7 35.8 8.8 7.8 16.7 19.4 42.0 47.0 11.6 22.0 43.7 9.5 30.5 70.1 14.0 20.1 76.3 34.4 43.0 19.5 23.4 29.6 28.7 12.5 93.7 28.8 26.1 12.7 33.8 12.0 14.2 130.1 78.4 29.5 19.1 5.0 47.1 22.7 31.1 41.1 9.6 11.1 22.6 183.0 72.6 50.4 16.1 31.7 10.8 57.0 30.1 64.9 15.3 16.7 14.7 24.2 63.1 16.9 12.2 11.2 36.0 33.1 50.4 78.1 19.1 14.3 298.0 72.4 8.7 12.9 39.5 171.0 6.4 42.5 29.5 116.7 50.6 37.4 2.5 14.8 69.2 18.4 4.8 442.2 84.1 52.7 69.2 43.9 67.8 21.2 92.5 41.9 25.5 58.7 37.3 33.6 28.0 159.7 50.9 326.8 34.6 21.1 325.0 24.8 30.8 25.5 20.6 221.1 28.0 18.5 18.1 52.8 27.9 175.4 82.2 38.1 228.0 24.6 28.4 32.0 36.9 25.1 48.0 42.7 35.8 47.0 34.4 29.6 33.8 130.8 3.2 13.1 37.2 77.0 55.2 12.7 9.1 8.6 34.7 12.0 11.4 195.6 12.8 3.2 9.2 12.5 5.3 114.2 9.2 33.2 13.7 5.1 50.4 32.6 166.3 26.9 32.6 15.1 6.4 18.9 38.0 7.7 78.0 78.6 15.6 147.4 8.6 259.8 11.8 73.2 8.4 12.2 392.6 609.2 17.5 17.4 362.7 149.4 31.9 630.0 21.1 62.8 19.1 85.0 10.3 14.0 7.2 26.0 19.0 6.5 9.0 1.6 39.3 39.5 26.7 39.1 55.7 28.8 10.6 51.6 5.6 58.3 4.0 8.5 6.7 APOL1 APOL ENSG00000100342 "Apolipoprotein L1" O14791 22 36253071-36267530 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 220.5" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 106.1;Glandular and luminal cells: 216.2;Hepatocytes: 115.6;Pancreatic endocrine cells: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 243.9;HDLM-2: 166.1;HHSteC: 120.3;RPTEC TERT1: 91.1;RT4: 146.8" "HPA018885, CAB056156" Supported "Secreted to blood" NA NA 1640000000 9200000000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "CAB056156: AB_2665576, HPA018885: AB_1844953" "unprognostic (1.05e-2)" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "unprognostic (8.98e-3)" "unprognostic (1.67e-1)" "unprognostic (8.28e-2)" "unprognostic (1.41e-2)" "prognostic unfavorable (5.35e-4)" "unprognostic (4.41e-2)" "unprognostic (1.58e-1)" "unprognostic (4.07e-3)" "unprognostic (5.15e-2)" "prognostic unfavorable (7.43e-6)" "unprognostic (1.93e-1)" "unprognostic (3.15e-2)" "unprognostic (5.05e-3)" "prognostic favorable (2.01e-5)" 45.3 15.8 8.1 62.5 8.2 4.2 28.4 7.8 9.8 53.8 9.4 32.0 32.7 38.8 17.7 25.7 36.7 69.0 29.5 7.4 8.4 44.5 220.5 59.5 23.1 10.0 8.5 24.8 9.0 4.9 14.1 53.0 9.6 37.5 27.2 0.9 29.7 52.2 11.7 7.1 28.9 65.4 9.0 56.8 64.9 7.9 10.8 24.9 18.0 13.8 23.6 117.7 29.9 8.2 21.6 5.1 0.1 0.6 46.8 44.6 14.2 2.3 9.0 13.7 38.6 0.6 34.4 7.0 243.9 24.8 31.3 5.3 0.0 19.2 3.6 166.1 0.2 6.1 3.2 41.4 120.3 2.4 20.2 8.3 1.7 38.0 0.8 2.0 27.3 1.3 23.8 85.1 2.4 0.2 8.5 2.1 0.6 0.6 0.2 13.6 2.6 3.2 91.1 146.8 1.9 0.1 10.9 5.8 2.1 0.3 0.8 7.8 24.7 29.5 12.4 3.2 1.5 6.5 4.0 1.6 16.0 12.4 4.6 15.6 6.1 5.5 12.6 6.8 10.7 2.6 8.1 11.2 4.3 1.4 4.6 6.3 16.1 22.4 10.3 0.5 5.4 7.2 8.1 8.2 7.8 9.8 7.4 8.4 10.0 8.5 9.6 9.0 10.8 8.2 37.4 57.7 34.3 0.3 7.2 1.7 21.4 73.5 2.8 0.5 6.3 3.0 3.6 15.7 67.1 18.4 2.1 11.0 12.6 31.2 0.0 37.8 0.8 106.1 48.8 41.3 7.7 3.8 0.1 20.0 8.2 27.3 45.9 216.2 11.4 4.3 49.6 115.6 9.1 0.0 0.1 17.7 32.6 15.8 5.3 1.4 27.4 10.9 0.0 7.5 19.4 0.1 36.0 0.0 0.0 105.1 19.9 24.0 15.0 31.2 20.5 2.1 60.5 1.3 6.6 5.5 10.6 0.4 0.4 3.4 2.3 6.7 12.9 1.6 4.6 62.5 ARHGAP26 "GRAF, KIAA0621, OPHN1L, OPHN1L1" ENSG00000145819 "Rho GTPase activating protein 26" Q9UNA1 5 142770377-143229011 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 237.3;Excitatory neurons: 611.6;Inhibitory neurons: 261.5;Late spermatids: 153.3;Microglial cells: 326.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "neutrophil: 24.7;NK-cell: 9.8" "Group enriched" "Detected in many" 4 "granulocytes: 24.7;NK-cells: 9.8" "Cell line enhanced" "Detected in many" "Karpas-707: 85.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035106, HPA035107" Enhanced Approved Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA035106: AB_2674465, HPA035107: AB_10669855" "prognostic favorable (2.05e-4)" "prognostic favorable (1.36e-4)" "prognostic favorable (6.95e-4)" "prognostic favorable (5.93e-6)" "unprognostic (1.19e-1)" "unprognostic (1.93e-2)" "unprognostic (4.19e-3)" "unprognostic (5.93e-2)" "unprognostic (2.22e-1)" "unprognostic (9.43e-3)" "unprognostic (7.19e-3)" "unprognostic (8.65e-2)" "unprognostic (3.21e-3)" "unprognostic (5.67e-2)" "unprognostic (2.70e-2)" "unprognostic (2.95e-2)" "prognostic favorable (2.88e-6)" 11.0 4.5 10.9 17.7 6.5 36.4 11.3 19.3 17.0 11.9 0.6 12.9 12.0 7.7 9.1 6.4 15.5 14.2 15.0 10.8 3.4 8.9 6.8 19.0 6.4 0.5 2.7 3.0 4.9 3.9 12.2 20.9 0.3 7.4 12.7 17.2 12.8 4.2 12.6 7.4 11.3 9.7 2.3 16.7 15.2 15.4 10.1 13.8 8.3 10.5 12.2 12.2 5.8 9.9 16.4 29.1 8.0 7.6 12.3 12.7 12.4 2.2 2.4 7.6 12.1 44.9 33.0 2.0 16.1 4.9 21.5 7.5 4.1 15.3 8.7 33.8 4.6 0.1 5.3 26.9 7.8 22.6 2.9 4.7 23.0 12.8 31.0 5.6 10.2 9.9 0.6 85.4 2.4 2.3 12.9 9.2 4.3 23.2 7.7 5.2 12.5 36.5 20.4 25.6 3.4 4.7 3.8 4.4 7.1 6.5 2.4 6.2 21.0 4.1 5.8 0.4 8.1 4.0 14.0 0.4 10.7 21.3 5.6 4.0 3.9 2.3 3.8 2.5 1.7 0.5 0.8 2.4 3.0 0.4 0.3 1.1 24.7 9.8 1.6 0.7 0.3 1.8 10.9 6.5 19.3 17.0 10.8 3.4 0.5 2.7 0.3 2.3 10.1 9.9 39.4 16.0 22.5 237.3 5.8 6.9 13.8 13.2 5.7 15.9 20.7 17.0 37.6 21.5 14.1 0.0 8.4 1.3 41.6 38.7 0.0 17.9 77.2 17.9 4.0 32.5 3.6 11.8 611.6 21.1 0.6 13.6 39.8 55.6 26.6 6.4 40.0 6.5 26.4 75.7 261.5 26.4 0.0 48.0 44.9 153.3 6.5 51.6 10.6 326.0 47.3 7.5 40.2 30.7 29.8 21.1 27.8 14.3 14.5 29.3 27.9 5.8 16.1 52.6 46.0 27.6 17.7 2.6 8.7 7.5 5.5 1.9 29.3 50.5 26.8 36.2 ARRDC3 "KIAA1376, TLIMP" ENSG00000113369 "Arrestin domain containing 3" Q96B67 5 91368631-91383317 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 394.2;Syncytiotrophoblasts: 339.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 115.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 20: HeLa - Mitochondria" "Cluster 41: Macrophages - Immune response" "unprognostic (2.28e-1)" "unprognostic (2.24e-1)" "unprognostic (9.42e-2)" "unprognostic (1.28e-1)" "unprognostic (4.07e-2)" "unprognostic (7.36e-2)" "unprognostic (1.57e-3)" "unprognostic (4.91e-2)" "unprognostic (2.44e-1)" "prognostic unfavorable (3.30e-4)" "unprognostic (1.50e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.25e-8)" "prognostic unfavorable (2.26e-4)" "unprognostic (1.34e-1)" "unprognostic (5.74e-2)" "unprognostic (2.15e-1)" 36.8 80.1 16.9 26.8 22.6 167.4 94.6 23.7 32.5 44.8 24.0 19.9 9.9 40.5 27.1 38.7 24.9 39.0 24.7 16.3 20.1 52.7 75.9 44.5 29.3 27.8 20.2 93.2 20.8 54.3 21.5 76.8 22.3 30.3 27.5 75.1 63.9 24.3 34.2 41.3 16.8 33.0 23.8 37.1 25.7 16.6 18.1 28.0 84.0 44.9 28.2 57.0 42.0 41.9 6.6 10.7 12.1 16.6 18.4 31.0 40.2 15.8 14.7 9.3 16.2 5.2 26.9 7.9 13.0 16.2 26.1 14.6 13.4 13.3 8.5 8.2 1.4 3.9 43.3 8.5 14.3 27.9 1.6 13.3 21.2 8.1 20.9 56.4 26.1 7.6 11.5 37.7 14.4 3.7 29.9 4.1 4.3 2.8 11.3 24.8 15.2 41.5 60.4 11.9 21.1 14.0 48.2 3.7 2.9 30.2 17.9 13.1 28.3 7.7 11.2 12.4 9.6 28.6 40.9 16.1 45.8 16.4 8.7 28.7 15.2 20.4 29.1 13.1 21.1 12.3 18.3 22.8 9.3 9.4 24.0 37.7 115.3 14.9 22.2 2.2 21.9 19.9 16.9 22.6 23.7 32.5 16.3 20.1 27.8 20.2 22.3 23.8 18.1 41.9 53.8 51.3 166.5 6.5 47.0 112.0 17.6 51.2 9.1 30.9 89.5 48.5 34.5 20.0 72.4 97.5 31.3 89.9 110.2 21.2 154.6 72.6 27.1 28.9 43.1 143.3 73.0 37.1 10.5 79.5 81.6 95.7 38.7 51.4 37.3 36.4 37.5 155.1 48.7 32.0 15.5 32.4 10.2 106.9 394.2 22.3 21.1 100.3 120.9 14.0 56.6 97.0 50.4 13.6 28.3 41.2 16.1 15.1 58.8 31.2 9.3 57.3 28.5 67.2 19.7 32.1 54.9 8.1 9.6 55.6 118.3 339.4 66.3 23.4 20.2 22.7 ATG9B "APG9L2, FLJ14885, NOS3AS, SONE" ENSG00000181652 "Autophagy related 9B" Q674R7 7 151012209-151024499 "Metabolic proteins, Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 8.3;skin 1: 11.5" "Cell type enhanced" "Detected in many" "Early spermatids: 50.7;Endometrial ciliated cells: 28.6;Late spermatids: 30.3;Respiratory ciliated cells: 25.9;Syncytiotrophoblasts: 115.5" "Cancer enhanced" "Detected in many" "testis cancer: 6.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 8.9" "Lineage enriched" "Detected in many" 5 "T-cells: 8.9" "Group enriched" "Detected in some" 5 "BEWO: 13.0;CAPAN-2: 4.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (1.59e-1)" "unprognostic (2.18e-2)" "unprognostic (1.31e-1)" "unprognostic (5.03e-2)" "unprognostic (1.53e-3)" "unprognostic (1.05e-3)" "unprognostic (2.79e-3)" "unprognostic (6.66e-2)" "unprognostic (2.38e-3)" "unprognostic (6.76e-2)" "unprognostic (2.02e-1)" "unprognostic (5.06e-2)" "unprognostic (2.08e-6)" "unprognostic (2.82e-2)" "unprognostic (2.70e-2)" "unprognostic (6.34e-2)" "unprognostic (2.63e-1)" 0.0 0.5 1.1 0.4 1.7 0.2 0.2 0.4 1.0 1.7 0.3 0.0 0.0 0.4 1.1 8.3 1.0 0.2 0.0 0.5 2.1 0.0 0.0 0.2 0.8 2.0 1.7 0.1 0.0 0.0 1.5 4.1 1.1 0.2 0.0 0.8 0.5 0.0 0.2 11.5 0.0 0.0 1.0 0.1 0.1 2.0 2.1 0.3 0.1 0.0 0.8 0.1 1.6 0.4 0.6 0.0 0.7 0.1 0.0 0.0 13.0 0.0 0.0 0.0 0.0 0.1 4.2 0.3 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.6 0.2 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 1.5 0.4 0.6 0.0 1.1 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.2 1.1 0.0 1.0 0.9 5.0 1.3 0.0 1.6 8.9 3.4 0.0 0.4 0.1 0.7 5.4 1.4 1.1 1.7 0.4 1.0 0.5 2.1 2.0 1.7 1.1 1.0 2.1 0.4 0.4 0.0 0.0 0.0 2.8 0.0 0.2 1.9 0.6 4.0 0.7 0.9 1.4 1.5 1.6 0.0 0.0 10.2 1.5 0.3 0.0 0.3 50.7 28.6 3.3 1.1 0.0 0.0 2.7 0.2 2.5 0.5 0.0 15.4 14.7 7.8 2.2 0.0 1.9 0.0 7.7 0.0 4.1 0.3 0.4 30.3 0.6 0.8 0.0 0.0 0.3 0.5 1.0 0.5 0.6 3.8 0.0 0.7 0.4 0.3 0.0 0.1 25.9 0.6 0.0 0.0 0.9 19.8 12.7 0.8 0.3 115.5 4.7 0.1 0.2 1.9 BAALC ENSG00000164929 "BAALC binder of MAP3K1 and KLF4" Q8WXS3 8 103140713-103230305 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 300.9;choroid plexus: 108.2" "Cell type enhanced" "Detected in many" "Adipocytes: 67.8;Astrocytes: 198.2;Excitatory neurons: 131.4;Inhibitory neurons: 62.3;Muller glia cells: 132.4;Oligodendrocyte precursor cells: 125.7" "Cancer enriched" "Detected in many" 8 "glioma: 139.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "NK-cell: 3.7" "Lineage enriched" "Detected in single" 28 "NK-cells: 3.7" "Cell line enhanced" "Detected in many" "AF22: 51.7;BJ hTERT+: 18.1;SCLC-21H: 27.9;SH-SY5Y: 20.5;U-87 MG: 75.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027132, HPA068307" Approved Supported Nucleoplasm,Cytosol No NA "Cluster 48: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol Nucleoplasm "HPA027132: AB_10600985, HPA068307: AB_2685971" "unprognostic (1.68e-1)" "unprognostic (9.17e-3)" "unprognostic (1.40e-2)" "unprognostic (4.62e-4)" "unprognostic (1.75e-2)" "unprognostic (2.84e-2)" "unprognostic (1.39e-1)" "unprognostic (7.87e-2)" "unprognostic (2.00e-1)" "unprognostic (4.99e-2)" "unprognostic (4.17e-2)" "unprognostic (2.18e-2)" "unprognostic (7.58e-2)" "unprognostic (2.51e-3)" "unprognostic (2.76e-2)" "unprognostic (1.70e-1)" "unprognostic (9.27e-3)" 9.3 15.6 196.7 2.1 209.2 3.4 7.0 182.2 226.6 1.6 108.2 3.1 0.9 1.7 0.4 0.7 3.8 1.6 3.1 201.1 206.8 4.3 2.9 7.3 1.4 240.0 237.4 3.3 2.1 0.4 25.9 5.3 219.5 1.1 1.6 19.4 1.0 0.9 2.0 2.0 2.7 1.8 229.2 14.5 2.4 1.3 300.9 0.6 4.5 1.4 0.8 2.5 1.4 205.3 0.5 3.0 51.7 0.5 0.5 14.9 0.0 2.6 18.1 0.1 0.2 0.5 0.1 0.2 0.5 10.1 0.2 0.8 0.9 0.1 0.1 0.1 3.1 0.5 0.8 0.1 1.2 0.0 1.1 3.0 2.9 0.6 0.0 2.7 0.4 0.1 0.0 0.4 0.1 0.4 0.0 0.2 1.3 0.4 1.0 0.2 0.3 1.2 0.0 0.1 27.9 20.5 0.6 0.0 0.1 4.5 0.2 0.3 3.0 16.0 1.0 0.4 1.0 0.0 0.2 0.2 75.7 0.3 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.2 196.7 209.2 182.2 226.6 201.1 206.8 240.0 237.4 219.5 229.2 300.9 205.3 67.8 0.0 1.8 198.2 0.3 5.5 0.7 4.5 0.6 2.1 2.0 1.1 0.8 17.2 5.9 0.0 0.0 0.1 2.1 0.3 7.9 32.0 2.9 15.6 2.3 33.4 17.8 6.1 131.4 25.6 0.1 1.6 0.0 34.0 0.0 0.0 23.6 0.8 0.9 0.0 62.3 3.4 22.4 1.3 6.2 8.7 1.5 2.1 14.2 18.7 4.6 132.4 2.1 125.7 46.1 4.1 1.2 0.0 0.8 0.8 0.1 0.1 21.7 3.3 0.0 2.1 8.1 0.1 0.1 0.3 4.0 0.0 1.3 0.3 0.1 1.1 BDKRB1 "B1BKR, BKR1, bradyb1" ENSG00000100739 "Bradykinin receptor B1" P46663 14 96256210-96268967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 23.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 40.8;Basal squamous epithelial cells: 41.5;Fibroblasts: 17.0;Squamous epithelial cells: 22.5;Suprabasal keratinocytes: 17.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 32.0;fHDF/TERT166: 18.8;HHSteC: 29.2;hTEC/SVTERT24-B: 29.2;U-2197: 27.9;U-87 MG: 90.1" "Low region specificity" "Detected in single" HPA002935 Approved NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA002935: AB_1078274" "unprognostic (6.15e-2)" "unprognostic (2.78e-2)" "unprognostic (9.40e-2)" "unprognostic (3.06e-3)" "unprognostic (6.76e-2)" "unprognostic (1.11e-2)" "unprognostic (3.31e-2)" "unprognostic (2.34e-3)" "unprognostic (2.23e-2)" "unprognostic (2.96e-2)" "unprognostic (4.80e-3)" "unprognostic (2.36e-1)" "unprognostic (9.96e-6)" "unprognostic (2.33e-1)" "unprognostic (8.82e-2)" "unprognostic (2.33e-3)" "unprognostic (4.66e-2)" 10.7 0.2 0.4 5.2 0.7 0.0 1.2 1.3 0.9 6.9 0.3 4.2 1.8 0.9 0.6 13.4 5.1 14.1 1.6 0.5 0.3 8.3 0.2 1.3 0.1 0.5 0.4 0.4 6.5 0.0 0.2 0.7 0.5 1.5 2.7 0.2 1.9 0.2 0.1 3.3 3.6 6.0 0.3 0.1 4.5 2.3 0.4 0.1 1.1 0.5 0.4 23.4 7.4 0.6 0.5 1.4 0.0 1.2 2.9 9.9 0.1 2.3 32.0 3.1 0.5 0.0 0.6 0.0 0.1 18.8 1.4 2.4 0.0 0.4 5.0 0.3 0.1 0.0 2.7 0.0 29.2 0.0 0.1 1.0 2.4 29.2 0.6 0.2 0.0 0.0 0.0 0.1 4.2 0.4 0.0 0.0 0.0 1.7 0.2 0.0 7.2 0.2 0.2 0.1 0.7 0.0 8.2 2.4 0.0 0.3 0.0 0.0 0.0 9.5 0.6 27.9 1.8 4.6 9.3 0.0 90.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.7 1.3 0.9 0.5 0.3 0.5 0.4 0.5 0.3 0.4 0.6 1.4 0.0 0.5 0.0 0.0 40.8 2.9 9.0 41.5 1.7 0.0 0.3 0.8 0.0 3.2 0.0 0.0 0.3 0.0 5.5 7.9 2.3 1.1 0.9 3.7 5.0 0.0 0.0 0.4 1.2 1.4 17.0 0.5 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.1 8.2 0.0 6.1 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.3 4.9 0.4 0.0 1.6 2.3 0.1 3.3 0.1 0.0 1.6 2.5 0.9 1.3 22.5 17.2 1.5 0.2 0.0 0.4 2.8 BDKRB2 BK-2 ENSG00000168398 "Bradykinin receptor B2" P30411 14 96204679-96244166 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 41.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.3;Endothelial cells: 18.2;Fibroblasts: 25.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 49.2;BJ hTERT+: 94.5;U-87 MG: 39.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA003551, HPA050841" Approved Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA003551: , HPA050841: AB_2681254" "unprognostic (1.03e-1)" "unprognostic (7.90e-2)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (8.79e-3)" "unprognostic (2.68e-2)" "unprognostic (1.93e-1)" "unprognostic (4.66e-2)" "unprognostic (1.94e-1)" "unprognostic (2.84e-2)" "unprognostic (3.19e-1)" "unprognostic (1.72e-1)" "unprognostic (3.32e-3)" "unprognostic (3.11e-2)" "unprognostic (9.40e-2)" "unprognostic (9.90e-2)" "unprognostic (1.49e-2)" 14.0 1.4 0.8 5.5 1.0 0.0 5.8 3.8 1.1 15.6 0.9 12.4 7.9 6.7 2.4 17.2 7.2 20.8 1.2 0.9 0.8 13.4 0.7 2.5 0.3 4.9 1.3 1.0 9.4 0.9 0.8 1.3 5.0 4.8 12.2 0.0 3.5 6.2 0.9 5.4 9.7 10.2 1.0 0.1 4.9 0.2 1.5 0.9 3.6 1.8 1.7 41.1 15.4 1.2 1.7 6.1 0.1 11.0 16.2 49.2 0.0 5.5 94.5 3.2 3.7 0.3 10.4 0.0 0.2 8.7 3.7 14.8 0.0 2.4 2.8 1.2 0.1 0.0 1.1 0.0 7.8 0.0 0.0 15.1 7.5 9.4 4.7 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.1 0.1 20.4 0.0 0.0 2.2 0.0 3.2 0.0 3.4 1.1 1.8 15.6 0.1 2.1 1.0 0.0 0.0 0.3 0.3 3.3 0.1 0.2 0.0 0.0 39.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 1.0 3.8 1.1 0.9 0.8 4.9 1.3 5.0 1.0 1.5 1.2 8.2 3.2 3.1 0.0 0.0 9.2 0.7 5.3 6.8 0.0 0.2 0.5 0.6 10.0 11.6 9.2 0.0 1.2 0.0 19.3 7.9 11.5 0.0 7.5 16.1 18.2 7.1 0.0 1.8 3.8 3.6 25.8 1.1 4.6 0.0 0.0 3.3 0.2 0.2 0.0 0.4 7.2 8.2 0.0 15.2 0.0 0.9 0.4 5.4 0.0 0.0 0.0 0.0 1.0 1.9 6.9 6.2 1.2 0.0 1.0 10.6 0.2 12.5 0.0 0.0 4.5 1.2 0.0 0.0 15.3 5.8 4.0 0.3 0.1 0.9 2.9 BMP6 "VGR, VGR1" ENSG00000153162 "Bone morphogenetic protein 6" P22004 6 7726099-7881728 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 23.0;Hepatic stellate cells: 16.8;Inhibitory neurons: 22.8;Microglial cells: 74.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.1" "Cell line enhanced" "Detected in many" "EFO-21: 37.0;HUVEC TERT2: 149.6;Karpas-707: 81.6;SiHa: 70.0;TIME: 74.3;U-266/84: 41.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002773, HPA062683" Approved Approved Mitochondria "Secreted to blood" No No 4970000 46000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "CAB002773: , HPA062683: AB_2684832" "prognostic favorable (6.45e-4)" "unprognostic (2.99e-1)" "unprognostic (4.20e-1)" "unprognostic (6.71e-2)" "unprognostic (2.44e-1)" "unprognostic (7.27e-2)" "unprognostic (4.66e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "unprognostic (6.94e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (1.26e-1)" "unprognostic (1.82e-2)" "unprognostic (8.29e-2)" "unprognostic (2.95e-1)" "unprognostic (2.29e-3)" 16.5 3.1 5.1 2.2 5.9 0.4 12.7 3.9 6.2 3.2 7.8 3.7 3.0 3.5 0.6 2.0 2.4 2.1 5.1 3.9 3.7 17.8 1.9 9.1 1.5 4.9 4.5 8.2 0.6 0.6 4.6 18.1 4.7 2.8 2.7 0.1 2.3 2.6 3.1 3.5 3.0 2.3 4.8 4.6 4.7 2.2 5.7 0.9 1.5 1.3 2.4 3.3 3.0 4.1 0.9 2.4 0.3 0.0 0.4 0.3 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 37.0 1.1 1.6 0.5 1.1 0.2 0.0 0.0 5.7 15.9 21.8 1.4 0.8 1.1 16.7 0.0 0.0 0.7 2.4 9.6 149.6 0.0 0.0 81.6 0.0 0.3 0.0 0.0 0.8 0.5 12.0 0.6 0.0 15.3 0.5 0.0 12.3 0.0 70.0 0.0 0.0 9.3 0.0 0.0 74.3 0.0 4.7 0.5 2.6 11.3 41.3 0.1 2.3 0.0 1.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 5.1 5.9 3.9 6.2 3.9 3.7 4.9 4.5 4.7 4.8 5.7 4.1 23.0 0.0 0.5 1.6 1.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 3.5 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.8 0.2 8.9 0.0 0.0 7.8 0.0 0.1 2.0 0.0 2.0 0.0 1.5 16.8 0.6 0.3 0.0 22.8 0.0 0.0 0.8 2.1 4.2 0.0 1.5 1.8 74.0 0.7 0.0 0.0 0.0 0.3 0.1 0.0 0.0 6.8 0.3 0.0 0.0 0.3 0.0 0.0 4.7 0.4 0.1 1.3 0.1 0.1 0.3 0.4 0.4 0.0 0.0 C2CD4B "FAM148B, NLF2" ENSG00000205502 "C2 calcium dependent domain containing 4B" A6NLJ0 15 62163535-62165285 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "pancreas: 99.3" "Cell type enhanced" "Detected in many" "Adipocytes: 169.8;Endothelial cells: 116.2;Enteroendocrine cells: 214.4;Glandular and luminal cells: 128.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HUVEC TERT2: 1.9" HPA046880 Uncertain NA NA "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "HPA046880: AB_10959458" "unprognostic (6.60e-2)" "prognostic favorable (4.22e-4)" "unprognostic (2.24e-2)" "unprognostic (1.25e-1)" "unprognostic (4.15e-1)" "unprognostic (4.06e-3)" "unprognostic (2.29e-1)" "unprognostic (5.02e-2)" "unprognostic (3.36e-2)" "unprognostic (2.33e-1)" "unprognostic (5.30e-2)" "unprognostic (1.83e-1)" "unprognostic (6.16e-3)" "unprognostic (7.89e-2)" "unprognostic (5.24e-1)" "unprognostic (8.64e-3)" "unprognostic (1.48e-1)" 23.1 1.2 1.5 0.6 1.0 3.0 19.6 0.8 1.2 7.2 0.5 2.5 2.2 4.1 0.0 1.6 2.8 1.6 6.3 0.9 0.9 5.5 1.9 13.0 0.4 1.5 1.3 1.0 99.3 0.3 6.5 0.4 1.5 2.3 0.4 0.0 1.6 0.2 2.8 4.7 2.4 0.7 1.7 0.5 24.4 1.0 2.1 2.7 2.7 1.3 0.0 5.0 2.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.0 0.8 1.2 0.9 0.9 1.5 1.3 1.5 1.7 2.1 0.9 169.8 3.2 5.5 0.0 0.1 6.8 3.0 0.1 0.6 0.8 14.5 4.3 1.3 5.7 0.9 1.8 0.0 0.0 0.9 6.1 0.0 2.1 0.0 40.4 15.2 116.2 214.4 0.0 0.0 24.0 0.0 3.2 17.9 128.9 2.5 0.0 11.4 0.4 0.4 0.0 0.1 22.5 6.1 1.0 12.1 0.0 0.0 1.3 3.6 1.9 1.6 0.1 0.0 0.0 0.0 9.8 1.3 0.0 0.1 2.4 1.3 0.0 0.1 0.6 0.0 6.8 4.1 0.1 0.4 0.8 7.0 0.0 1.7 0.5 4.3 3.5 C7orf57 ENSG00000164746 "Chromosome 7 open reading frame 57" Q8NEG2 7 48035511-48061304 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.0;choroid plexus: 6.4;fallopian tube: 13.9" "Group enriched" "Detected in some" 5 "Endometrial ciliated cells: 52.7;Respiratory ciliated cells: 127.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 3.4;hTERT-HME1: 5.5;U-266/70: 3.2;U-698: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021286 Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 49: Ciliated cells - Cilium organization" "HPA021286: AB_1845760" "unprognostic (1.74e-2)" "unprognostic (4.82e-2)" "unprognostic (3.13e-2)" "unprognostic (1.28e-2)" "unprognostic (2.77e-3)" "unprognostic (3.22e-2)" "unprognostic (1.21e-2)" "unprognostic (1.32e-1)" "unprognostic (3.29e-1)" "unprognostic (1.37e-1)" "unprognostic (4.98e-2)" "unprognostic (2.88e-1)" "unprognostic (3.93e-5)" "unprognostic (5.17e-3)" "unprognostic (6.18e-2)" "unprognostic (3.42e-3)" "unprognostic (1.20e-1)" 0.0 0.0 0.7 0.0 0.8 0.2 0.1 0.5 0.3 0.4 6.4 0.0 0.1 0.4 0.0 0.8 13.9 0.0 0.1 0.7 0.9 0.1 0.0 2.2 0.0 4.0 3.8 0.0 0.0 0.6 0.2 0.0 2.3 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 3.7 0.9 0.0 0.2 0.0 0.1 0.0 0.4 2.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.2 0.0 1.3 0.0 0.1 0.1 3.4 0.2 0.0 0.5 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.3 0.5 0.2 0.3 3.2 0.5 1.9 0.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.8 0.5 0.3 0.7 0.9 4.0 3.8 2.3 2.9 0.9 2.0 0.0 0.0 3.0 0.3 0.1 0.0 0.0 4.7 0.0 0.0 0.0 0.1 1.0 0.0 15.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 5.9 52.7 0.6 0.2 0.0 0.0 0.5 0.0 0.1 0.6 0.0 1.1 2.5 0.0 0.0 0.0 0.1 0.0 0.5 0.0 6.1 0.0 0.4 3.5 0.0 0.3 0.0 0.0 0.0 1.1 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 127.6 0.9 0.0 0.0 2.7 16.1 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.1 CCRL2 "ACKR5, CKRX, CRAM-A, CRAM-B, HCR" ENSG00000121797 "C-C motif chemokine receptor like 2" O00421 3 46407166-46412997 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 35.0;Erythroid cells: 26.5;Hofbauer cells: 42.7;Kupffer cells: 22.1;Langerhans cells: 36.5;Macrophages: 56.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 21.0;OE19: 8.4;PC-3: 15.3;RT4: 8.3;TIME: 15.4;U-266/84: 8.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043238 Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 36: HEL - Hemostasis" "Cluster 41: Macrophages - Immune response" "HPA043238: AB_10794924" "unprognostic (3.94e-1)" "unprognostic (7.02e-2)" "prognostic favorable (3.72e-5)" "unprognostic (1.64e-1)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (1.46e-1)" "unprognostic (1.62e-1)" "unprognostic (4.10e-2)" "unprognostic (4.17e-2)" "unprognostic (9.73e-2)" "unprognostic (1.98e-2)" "unprognostic (5.17e-2)" "unprognostic (1.78e-1)" "unprognostic (3.04e-2)" "unprognostic (2.57e-1)" "prognostic favorable (9.67e-5)" 11.7 1.6 2.1 11.4 2.1 9.0 8.4 2.2 3.7 2.3 2.2 11.5 11.7 1.2 0.6 0.9 1.1 5.5 2.7 2.1 2.2 2.2 4.4 12.4 4.9 2.8 2.3 0.5 1.5 0.8 0.8 5.1 3.1 0.8 10.4 0.2 0.9 0.8 1.1 0.7 12.1 2.5 2.6 8.5 5.5 0.3 2.9 7.7 1.3 1.1 3.8 6.0 1.1 3.3 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 1.2 0.0 0.2 0.0 0.0 2.8 0.0 0.0 0.3 0.7 4.6 0.0 21.0 0.0 0.0 0.0 1.4 0.2 0.0 0.0 5.0 0.2 0.0 7.2 4.2 2.8 0.1 5.0 0.0 1.6 2.6 0.0 8.4 15.3 0.4 0.3 0.0 0.0 8.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 15.4 0.6 0.3 0.7 0.3 0.0 8.6 0.2 7.5 6.5 0.0 8.7 15.4 4.3 2.8 22.1 3.4 1.7 1.6 4.7 9.9 3.9 1.0 2.5 2.6 6.7 10.1 3.0 4.7 5.0 2.1 2.1 2.2 3.7 2.1 2.2 2.8 2.3 3.1 2.6 2.9 3.3 35.0 0.0 4.7 0.0 4.4 2.0 0.2 0.2 0.0 0.0 0.4 0.4 1.1 1.5 1.2 0.0 0.0 0.3 4.5 19.5 0.0 0.6 0.1 0.1 0.2 12.1 0.0 26.5 0.0 8.8 1.2 1.4 4.6 0.1 9.5 0.1 6.4 0.4 42.7 0.0 0.0 16.6 0.0 22.1 36.5 0.0 0.0 56.2 1.8 1.9 6.7 0.0 0.0 0.0 0.0 9.8 12.4 0.0 4.2 0.2 17.2 0.2 0.6 0.0 0.0 0.6 0.5 0.0 0.0 0.0 1.1 2.5 6.4 0.4 9.2 1.1 CD274 "B7-H, B7-H1, B7H1, PD-L1, PDCD1LG1, PDL1" ENSG00000120217 "CD274 molecule" Q9NZQ7 9 5450503-5470566 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 16.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 27.7;granulocytes: 28.4;Langerhans cells: 50.9;monocytes: 42.4;Syncytiotrophoblasts: 44.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 6.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.6" "Cell line enhanced" "Detected in many" "HDLM-2: 89.6;HHSteC: 55.5;U-251 MG: 98.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003528, CAB076385" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane, Actin filaments" Nucleoplasm "CAB076385: AB_2687655, HPA003528: " "prognostic favorable (8.89e-4)" "unprognostic (4.54e-2)" "prognostic favorable (1.64e-5)" "unprognostic (1.27e-2)" "unprognostic (2.96e-2)" "unprognostic (1.08e-1)" "unprognostic (4.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.68e-2)" "unprognostic (5.67e-4)" "unprognostic (7.39e-3)" "unprognostic (1.69e-2)" "unprognostic (1.24e-2)" "unprognostic (1.35e-1)" "unprognostic (1.49e-2)" "unprognostic (2.67e-1)" "unprognostic (9.02e-2)" 2.6 2.0 1.0 10.3 0.9 1.9 1.5 0.9 1.2 1.8 0.6 1.4 2.7 1.5 1.8 2.5 1.8 4.0 8.9 0.8 1.9 2.6 3.4 16.8 6.6 1.8 1.6 1.5 1.9 5.0 2.6 6.8 2.0 2.0 2.1 1.2 1.5 1.5 4.5 0.7 1.9 2.2 1.7 10.2 1.9 0.9 1.6 13.0 3.5 4.3 5.3 7.2 1.3 1.1 15.6 0.2 0.0 0.5 0.1 0.1 0.0 30.5 25.7 7.7 10.4 0.0 5.0 0.2 0.6 0.8 3.8 0.6 0.0 13.2 24.6 89.6 0.0 9.0 0.3 0.0 55.5 0.0 0.0 0.5 0.1 15.7 22.9 7.7 15.0 0.9 0.0 2.9 23.4 0.0 0.4 0.1 0.0 0.0 0.3 0.1 4.2 0.8 1.6 0.3 0.0 0.3 0.4 2.4 1.9 2.2 0.1 0.3 28.1 16.1 5.1 0.5 98.1 0.5 0.2 0.3 5.4 0.3 0.2 6.6 0.0 0.2 0.7 0.1 1.2 0.5 1.4 1.1 0.0 0.1 0.7 0.4 3.6 0.3 0.0 0.0 0.7 0.4 1.0 0.9 0.9 1.2 0.8 1.9 1.8 1.6 2.0 1.7 1.6 1.1 3.0 12.8 11.4 0.7 1.9 4.6 1.5 4.4 1.8 1.4 1.4 1.3 7.8 0.0 2.9 0.0 0.0 6.1 2.4 2.6 0.0 5.9 1.0 1.4 0.3 5.5 0.0 3.2 1.9 4.4 27.7 1.9 0.5 0.9 28.4 0.2 7.1 0.8 5.7 0.0 3.3 0.5 4.1 2.9 50.9 0.2 0.3 4.2 3.6 8.4 42.4 0.5 1.0 1.0 0.9 19.0 0.1 0.4 2.2 2.1 1.9 0.4 4.0 0.2 0.0 2.3 0.9 1.0 0.8 1.2 2.6 44.5 3.1 0.1 0.4 2.0 CDC37 P50CDC37 ENSG00000105401 "Cell division cycle 37, HSP90 cochaperone" Q16543 19 10391133-10420121 "Cancer-related genes, Predicted intracellular proteins, Transporters" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003928, CAB004214" Supported Supported Cytosol NA NA 610000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 24: NB-4 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB004214: AB_627232, HPA003928: AB_1846373" "unprognostic (2.40e-1)" "unprognostic (1.06e-1)" "unprognostic (1.27e-1)" "unprognostic (2.33e-2)" "unprognostic (2.46e-3)" "unprognostic (6.21e-2)" "unprognostic (1.37e-1)" "unprognostic (7.90e-2)" "unprognostic (1.25e-1)" "unprognostic (7.61e-3)" "unprognostic (1.96e-2)" "unprognostic (1.82e-2)" "unprognostic (1.84e-2)" "prognostic favorable (2.33e-4)" "unprognostic (5.80e-2)" "unprognostic (1.23e-1)" "unprognostic (3.02e-2)" 149.9 93.6 82.2 81.3 84.6 89.5 130.6 75.0 104.2 111.4 72.1 109.9 58.1 110.0 34.2 125.7 98.5 39.8 186.0 86.3 85.8 123.2 102.2 129.9 66.5 85.9 85.8 105.9 100.3 59.3 74.6 62.7 88.1 105.0 48.2 34.6 96.6 52.2 313.2 100.9 96.3 50.2 75.7 137.5 102.8 77.5 82.5 69.3 100.8 222.6 52.4 110.3 103.0 87.8 279.2 181.2 95.5 137.5 128.8 111.8 122.9 322.8 144.6 198.3 168.8 209.1 106.7 165.3 254.7 198.3 117.2 169.9 130.6 208.7 136.4 133.6 387.2 313.9 147.2 300.9 202.5 183.9 137.9 136.9 112.5 231.8 104.0 113.5 258.1 142.2 248.2 193.8 156.1 265.3 184.3 450.2 234.6 175.5 317.8 181.0 128.3 190.3 185.1 178.2 111.5 161.9 151.5 158.1 143.1 72.7 108.4 195.7 290.0 230.8 133.9 319.9 262.2 261.3 276.5 204.4 181.4 294.1 191.2 77.2 110.8 97.1 114.4 107.9 103.1 73.2 91.8 103.5 105.2 62.9 70.0 81.8 60.2 101.1 112.6 89.4 106.8 145.6 82.2 84.6 75.0 104.2 86.3 85.8 85.9 85.8 88.1 75.7 82.5 87.8 420.1 54.5 95.5 51.6 163.7 148.6 119.3 149.0 127.5 78.0 85.0 75.8 71.3 75.8 114.8 64.4 39.6 188.9 166.1 192.3 101.8 199.8 119.0 88.2 120.5 267.5 81.3 89.8 35.0 199.0 430.2 108.3 226.8 126.4 134.3 90.8 172.1 45.3 210.2 89.2 24.6 181.3 105.8 83.9 313.8 253.8 106.2 165.6 138.7 29.0 165.1 75.8 135.9 21.1 32.5 297.6 183.5 103.4 170.5 120.1 117.9 89.7 78.2 84.4 78.9 94.4 138.6 72.4 73.5 138.1 133.7 242.4 164.2 123.0 186.1 156.1 CDC42SE2 "FLJ21967, SPEC2" ENSG00000158985 "CDC42 small effector 2" Q9NRR3 5 131245493-131398447 "Predicted intracellular proteins" "Cell shape, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-cells: 242.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038624 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA038624: AB_10670783" "unprognostic (1.26e-1)" "unprognostic (1.19e-2)" "prognostic favorable (4.50e-5)" "unprognostic (2.37e-3)" "unprognostic (7.38e-2)" "unprognostic (4.31e-2)" "unprognostic (2.91e-3)" "unprognostic (2.11e-1)" "unprognostic (2.37e-1)" "unprognostic (8.65e-3)" "unprognostic (2.18e-1)" "unprognostic (2.96e-1)" "unprognostic (2.08e-3)" "unprognostic (5.44e-2)" "unprognostic (3.31e-1)" "unprognostic (1.67e-1)" "prognostic favorable (7.50e-4)" 16.5 10.6 30.7 53.6 32.5 78.7 22.8 26.8 42.3 22.1 20.2 46.6 39.2 18.7 21.0 13.2 16.6 27.4 11.2 35.5 27.8 31.3 21.7 24.7 81.2 28.5 29.6 18.9 27.3 23.9 12.3 15.2 27.7 20.4 48.4 7.1 16.5 16.0 12.9 16.8 45.5 17.2 30.0 57.8 32.0 30.9 28.2 48.6 36.7 11.0 66.4 29.3 9.8 37.0 31.6 33.8 22.4 33.4 22.4 11.5 42.2 23.0 14.8 15.4 15.9 37.4 86.7 49.5 50.5 16.4 25.9 22.1 17.6 43.4 22.4 88.2 11.1 39.9 13.9 24.0 27.9 48.2 51.5 15.2 81.2 21.0 46.7 15.9 23.3 56.5 27.2 67.1 26.5 20.4 84.1 51.8 18.2 21.6 10.1 43.5 38.1 63.2 67.6 51.3 23.8 18.1 32.1 20.4 29.6 31.9 24.4 55.9 29.3 21.3 18.4 12.8 28.9 42.1 66.4 62.4 19.1 54.0 18.9 233.4 42.8 134.4 111.5 44.7 131.1 74.9 131.4 137.7 64.1 51.5 131.6 148.6 114.7 113.4 44.6 54.6 117.9 181.4 30.7 32.5 26.8 42.3 35.5 27.8 28.5 29.6 27.7 30.0 28.2 37.0 38.0 32.1 20.6 44.1 166.8 54.2 38.5 45.6 21.6 9.2 30.6 22.4 14.4 52.9 30.0 104.8 8.4 35.4 211.5 148.6 99.7 50.9 29.2 73.7 27.2 33.7 85.6 37.5 84.3 51.0 106.0 18.3 33.6 104.1 54.5 30.6 35.0 35.5 37.9 6.7 78.8 65.7 40.7 111.9 192.3 21.9 14.0 77.6 46.2 72.1 119.9 21.7 134.9 51.8 149.2 66.3 60.6 17.3 113.1 54.4 79.3 148.0 27.3 7.5 0.0 17.7 22.1 58.7 57.7 11.8 45.5 24.8 242.7 15.7 67.2 60.8 CDK17 "PCTAIRE2, PCTK2" ENSG00000059758 "Cyclin dependent kinase 17" Q00537 12 96278261-96400480 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 101.5;Oligodendrocytes: 259.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 134.8;TIME: 160.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015325 Approved Approved Nucleoplasm,Cytosol Yes No "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Cytosol" "HPA015325: AB_1855090" "unprognostic (4.35e-1)" "unprognostic (2.79e-1)" "unprognostic (2.70e-1)" "unprognostic (3.56e-1)" "unprognostic (1.50e-1)" "unprognostic (4.96e-3)" "unprognostic (5.22e-3)" "unprognostic (1.23e-1)" "unprognostic (3.23e-2)" "unprognostic (2.75e-2)" "unprognostic (2.44e-1)" "unprognostic (5.96e-2)" "prognostic unfavorable (1.09e-6)" "unprognostic (4.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.92e-2)" "unprognostic (1.70e-2)" 21.4 11.2 26.3 18.9 45.9 48.1 18.4 23.0 34.7 13.2 8.3 17.0 11.9 26.2 9.1 14.6 13.9 16.2 11.4 36.7 28.6 11.6 16.3 20.6 21.7 23.2 23.0 15.7 10.5 10.6 8.0 31.8 23.0 14.0 12.2 19.3 8.7 11.1 8.8 11.0 11.5 29.5 27.4 21.8 10.5 26.6 28.5 24.8 11.6 12.3 22.2 17.1 12.8 54.0 15.4 12.5 32.5 8.9 15.9 41.2 24.1 34.8 46.9 29.1 27.2 7.7 8.8 22.7 23.0 24.5 15.6 13.8 19.8 20.9 39.5 24.9 15.5 32.7 8.5 10.9 34.4 17.9 18.4 30.0 21.3 43.0 77.1 51.8 134.8 18.9 24.7 18.1 66.8 9.5 17.0 28.1 14.4 7.6 22.8 29.2 18.0 19.8 35.1 12.7 17.1 11.7 19.9 18.4 25.9 24.7 14.0 15.7 160.5 25.6 10.0 13.8 18.7 26.0 21.1 24.1 9.6 7.6 19.2 66.7 6.4 17.1 22.2 9.3 24.0 17.5 17.9 25.1 10.0 16.6 25.0 21.7 23.2 31.4 9.0 7.3 15.8 16.6 26.3 45.9 23.0 34.7 36.7 28.6 23.2 23.0 23.0 27.4 28.5 54.0 58.1 16.0 6.5 54.5 37.3 26.8 10.7 8.6 19.4 11.8 13.8 9.8 11.9 7.2 10.3 9.2 16.7 12.0 64.4 7.2 0.0 4.9 3.3 17.6 10.0 51.7 15.0 17.9 101.5 3.6 27.9 24.0 21.4 17.2 18.3 8.9 34.2 10.8 12.1 5.0 59.2 7.9 4.1 14.5 20.7 4.1 9.9 16.7 17.8 64.6 8.6 22.6 32.0 52.3 259.2 7.4 3.4 9.4 64.7 12.5 6.5 8.6 15.4 9.6 6.6 22.7 22.0 8.8 21.6 24.2 25.9 13.7 63.2 10.7 6.0 15.1 CDK2 ENSG00000123374 "Cyclin dependent kinase 2" P24941 12 55966781-55972789 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 92.8;Extravillous trophoblasts: 84.7;Melanocytes: 87.2;Syncytiotrophoblasts: 170.7" "Cancer enhanced" "Detected in all" "melanoma: 88.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 540.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013115, HPA066915" Enhanced Enhanced Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 28: Placenta - Pregnancy" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Centrosome, Cytosol" "CAB013115: AB_2536375, HPA066915: AB_2685748" "unprognostic (2.36e-2)" "unprognostic (2.60e-1)" "unprognostic (3.71e-2)" "unprognostic (1.83e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.94e-4)" "prognostic unfavorable (8.61e-5)" "unprognostic (3.48e-2)" "unprognostic (1.31e-1)" "unprognostic (4.67e-2)" "unprognostic (5.38e-3)" "unprognostic (4.69e-3)" "prognostic unfavorable (1.46e-10)" "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" "unprognostic (6.16e-2)" "unprognostic (6.75e-2)" 15.3 9.2 3.5 16.3 3.4 36.0 14.2 3.6 4.9 13.4 6.4 12.5 9.8 13.7 6.3 14.9 13.7 10.8 10.9 3.5 3.8 14.7 16.2 22.9 21.6 4.7 4.0 16.3 10.0 7.9 4.9 47.3 4.1 12.6 14.9 6.5 10.9 14.3 7.0 22.7 12.3 19.5 4.2 14.5 12.2 6.6 4.1 37.2 9.6 8.1 24.8 18.1 12.9 3.9 81.7 39.1 93.6 52.4 19.2 24.9 172.2 98.9 53.5 123.3 114.8 89.4 76.3 77.5 70.9 37.9 46.4 50.8 73.4 44.9 126.8 86.9 68.0 89.0 65.0 34.6 6.3 70.4 61.4 12.6 10.9 83.8 29.1 36.1 63.1 76.8 85.6 68.0 88.3 60.8 149.9 61.7 36.9 55.8 60.7 143.7 86.2 57.1 36.5 77.1 37.4 48.1 114.1 41.7 540.3 54.9 88.9 51.1 34.5 82.9 76.3 65.0 71.0 37.4 46.3 95.5 47.4 51.1 74.2 3.6 2.6 2.2 4.7 2.7 4.6 6.5 2.1 3.5 1.9 3.7 2.0 3.7 1.2 3.4 1.2 7.9 5.4 3.3 3.5 3.4 3.6 4.9 3.5 3.8 4.7 4.0 4.1 4.2 4.1 3.9 17.9 16.0 4.8 1.3 7.3 28.0 23.9 6.2 12.5 0.0 14.5 8.9 3.1 11.5 7.6 1.8 0.0 92.8 7.1 3.7 1.9 11.5 0.6 7.4 6.5 18.2 5.4 14.7 0.1 5.7 84.7 15.7 9.2 13.0 10.8 12.0 10.4 9.1 13.3 1.7 0.1 7.2 6.1 4.7 43.8 0.8 14.9 4.9 87.2 1.9 28.4 4.2 5.2 0.0 0.5 12.3 1.5 4.5 11.8 13.4 2.8 4.5 4.4 3.6 0.0 10.1 11.6 3.1 7.4 14.5 31.4 170.7 9.6 4.8 9.7 19.3 CDKN2B "CDK4I, INK4B, MTS2, P15, p15INK4b, TP15" ENSG00000147883 "Cyclin dependent kinase inhibitor 2B" P42772 9 22002903-22009305 "Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 36.2;intestine: 30.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 240.7;Pancreatic endocrine cells: 164.5;Proximal enterocytes: 139.0;Squamous epithelial cells: 142.0;Urothelial cells: 241.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 3.3;intermediate monocyte: 3.3;non-classical monocyte: 9.0" "Lineage enriched" "Detected in single" 17 "monocytes: 9.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 38.1;HaCaT: 35.0;HeLa: 33.9;hTERT-RPE1: 60.1;SiHa: 48.0;SK-MEL-30: 35.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB000349, HPA052838, HPA063327" Uncertain Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB000349: , HPA052838: , HPA063327: AB_2684987" "unprognostic (2.30e-1)" "unprognostic (9.23e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (4.47e-6)" "unprognostic (2.10e-1)" "unprognostic (7.40e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (2.01e-1)" "unprognostic (3.03e-2)" "unprognostic (3.19e-2)" "unprognostic (1.13e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.03e-4)" "unprognostic (9.14e-3)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" "unprognostic (7.28e-2)" 18.7 1.9 2.0 2.9 1.8 0.4 8.6 1.1 1.9 9.6 9.1 22.4 21.7 3.8 0.6 36.2 1.7 2.4 1.0 1.6 2.2 1.2 1.2 12.6 1.1 2.7 1.5 0.9 1.2 3.3 3.5 2.3 2.3 3.6 19.7 2.8 6.7 4.7 7.2 12.9 30.9 2.1 1.7 4.6 6.0 5.3 2.4 0.8 1.1 1.1 8.1 7.9 20.2 2.4 0.0 0.0 0.3 2.1 28.2 38.1 0.7 1.8 0.0 4.6 12.6 3.6 10.3 0.0 3.4 2.3 0.0 35.0 0.8 6.9 5.5 2.6 9.7 0.0 33.9 1.5 14.4 1.1 6.1 8.1 0.0 6.5 25.8 60.1 4.4 0.0 0.0 17.1 7.3 2.8 0.0 0.1 1.7 1.7 19.5 0.0 2.4 0.7 10.0 0.0 5.4 0.1 48.0 11.5 35.7 25.8 3.0 0.0 14.8 0.0 0.7 0.1 0.0 13.5 8.4 0.1 0.0 1.0 0.0 0.0 3.3 0.0 0.1 3.3 0.0 0.0 0.2 0.3 0.5 0.0 0.0 0.1 0.0 0.0 9.0 0.0 0.0 1.0 2.0 1.8 1.1 1.9 1.6 2.2 2.7 1.5 2.3 1.7 2.4 2.4 3.5 67.3 6.7 0.3 2.9 5.4 27.0 40.5 5.7 3.2 6.4 9.8 3.1 1.5 37.5 5.5 0.0 1.2 3.2 240.7 0.0 57.7 11.3 31.8 7.5 4.1 7.7 0.0 0.1 38.2 0.8 11.5 30.5 37.2 0.0 0.4 1.8 0.1 1.2 0.0 0.5 31.6 14.2 17.6 3.8 2.7 0.6 5.6 3.6 2.8 3.2 4.8 0.0 1.0 0.5 164.5 75.6 1.2 2.1 65.3 139.0 0.1 17.9 7.2 0.0 2.7 8.9 13.8 3.5 142.0 24.2 3.1 2.9 1.2 23.3 241.6 CEACAM19 CEAL1 ENSG00000186567 "CEA cell adhesion molecule 19" Q7Z692 19 44662278-44684359 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 7.9;Skeletal myocytes: 8.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 12.2;RPTEC TERT1: 15.8;TIME: 20.9" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hippocampal formation: 1.1" "HPA014462, HPA052865" Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 50: Non-specific - Ribosome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Nucleoli, Mitochondria" Nucleoplasm "HPA014462: AB_2669006, HPA052865: AB_2681976" "unprognostic (2.91e-1)" "unprognostic (5.29e-3)" "unprognostic (6.96e-3)" "unprognostic (1.45e-2)" "unprognostic (3.73e-2)" "unprognostic (8.43e-2)" "unprognostic (5.22e-2)" "unprognostic (1.15e-2)" "unprognostic (9.98e-2)" "unprognostic (1.14e-1)" "unprognostic (1.78e-3)" "unprognostic (1.77e-1)" "unprognostic (3.26e-9)" "unprognostic (8.01e-3)" "unprognostic (9.62e-2)" "unprognostic (1.31e-1)" "unprognostic (2.70e-1)" 3.9 5.6 3.7 1.3 3.7 1.5 3.8 4.9 5.1 7.0 3.5 4.7 3.0 5.2 1.7 5.1 6.8 2.4 11.7 4.0 3.8 9.4 8.2 8.2 1.1 2.8 3.0 6.6 8.9 1.5 7.0 2.2 2.7 7.8 3.4 2.4 5.7 3.1 13.8 12.4 3.8 3.1 1.9 3.5 4.6 5.7 3.7 0.9 6.5 3.4 2.2 4.2 8.7 4.7 5.1 10.3 1.5 1.0 3.5 4.0 3.8 2.8 4.2 0.9 1.8 0.4 1.1 0.1 1.0 3.8 1.0 6.2 2.6 1.1 0.8 1.5 5.8 0.1 6.7 1.7 3.6 0.2 1.0 1.3 10.0 2.6 6.1 12.2 2.4 0.7 0.3 0.3 1.4 1.2 0.0 0.6 0.9 1.4 1.1 0.0 1.8 0.2 15.8 1.2 1.9 0.5 1.1 1.1 0.9 1.4 1.4 0.3 20.9 0.4 6.8 1.5 0.9 0.1 0.3 0.0 0.5 2.0 1.7 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 3.7 3.7 4.9 5.1 4.0 3.8 2.8 3.0 2.7 1.9 3.7 4.7 3.6 3.2 2.2 2.0 0.0 2.0 0.9 2.1 1.2 2.9 1.9 1.5 4.5 1.5 2.4 0.0 0.0 0.2 0.1 2.1 0.0 1.6 3.8 0.9 0.9 4.1 1.8 0.0 7.9 3.3 0.2 1.0 3.6 2.4 0.0 0.8 4.6 2.6 0.3 0.0 6.1 2.3 4.1 0.6 0.8 1.9 3.1 0.5 0.0 1.9 0.4 0.3 1.0 2.0 2.4 4.5 2.6 2.6 0.0 1.8 1.2 0.4 1.8 0.6 0.0 8.8 1.7 3.1 0.9 1.2 6.0 0.0 0.2 1.6 2.5 0.9 CEBPG "GPE1BP, IG/EBP-1" ENSG00000153879 "CCAAT enhancer binding protein gamma" P53567 19 33373685-33382686 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012024 Enhanced Supported Nucleoplasm NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA012024: AB_1846503" "unprognostic (5.56e-2)" "unprognostic (1.35e-1)" "unprognostic (3.29e-3)" "prognostic unfavorable (7.97e-5)" "unprognostic (8.12e-2)" "unprognostic (2.35e-2)" "unprognostic (2.13e-1)" "unprognostic (5.42e-2)" "unprognostic (1.19e-2)" "unprognostic (2.10e-2)" "unprognostic (1.29e-1)" "unprognostic (2.74e-2)" "prognostic unfavorable (7.23e-4)" "unprognostic (1.16e-1)" "unprognostic (5.25e-2)" "unprognostic (8.87e-2)" "unprognostic (2.01e-2)" 19.1 8.8 16.0 14.2 16.9 15.4 15.1 17.6 23.8 11.0 12.4 30.2 34.1 12.0 9.1 20.1 11.9 11.4 14.8 15.6 19.3 12.9 34.6 16.0 12.4 17.0 17.6 5.3 28.3 15.1 11.0 16.8 17.6 12.0 28.8 17.3 13.5 9.4 47.4 27.7 35.3 14.6 18.7 9.7 18.8 12.5 19.0 14.1 25.7 44.2 13.8 16.3 14.2 18.4 33.4 29.7 30.9 31.0 14.8 21.6 41.8 24.8 22.1 21.9 26.4 35.3 14.4 54.0 19.1 11.8 26.2 16.6 54.8 25.0 37.5 91.7 23.3 29.1 15.6 34.5 49.3 49.1 31.0 28.6 121.0 27.7 86.7 11.1 27.7 45.1 39.3 49.7 17.9 20.4 33.0 25.7 17.5 94.2 18.2 35.1 21.0 22.5 12.4 19.9 61.1 37.2 25.8 26.7 61.3 22.6 22.7 96.8 26.7 22.2 26.3 23.8 39.6 28.4 27.0 32.4 23.4 53.2 31.4 7.5 9.7 4.4 3.6 11.8 4.3 4.6 4.9 5.6 10.3 3.7 5.2 5.0 0.8 3.0 19.1 3.2 6.0 5.6 16.0 16.9 17.6 23.8 15.6 19.3 17.0 17.6 17.6 18.7 19.0 18.4 61.3 19.2 13.2 2.6 30.5 124.3 95.8 51.5 67.7 11.3 32.8 31.9 15.1 48.6 29.6 14.7 8.4 42.6 27.6 160.5 19.6 37.0 90.3 43.2 14.9 50.4 35.3 22.3 11.7 54.1 71.5 26.1 34.1 26.6 26.0 9.5 31.4 66.2 45.6 3.3 8.3 81.8 34.6 35.4 65.1 74.5 6.8 34.4 28.4 10.3 63.9 27.7 28.8 6.0 3.9 75.8 107.7 9.1 30.5 70.2 115.7 30.4 49.4 12.9 6.6 24.7 31.5 76.4 45.2 57.8 155.7 74.8 29.4 5.1 67.8 120.4 CENATAC "CCDC84, DLNB14" ENSG00000186166 "Centrosomal AT-AC splicing factor" Q86UT8 11 118998138-119015793 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 9.1;Cardiomyocytes: 8.5;Cytotrophoblasts: 15.3;dendritic cells: 12.1;Hofbauer cells: 9.2;Plasma cells: 8.1;Syncytiotrophoblasts: 7.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 19.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039906, HPA071715" Uncertain Approved Nucleoplasm No No "Cluster 37: B-cells - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA039906: AB_2676740, HPA071715: AB_2686436" "unprognostic (5.83e-2)" "unprognostic (2.64e-1)" "unprognostic (1.36e-1)" "unprognostic (8.12e-2)" "unprognostic (1.54e-1)" "unprognostic (4.06e-2)" "unprognostic (1.15e-2)" "unprognostic (1.03e-3)" "unprognostic (3.60e-3)" "unprognostic (3.45e-2)" "unprognostic (4.64e-3)" "unprognostic (1.20e-2)" "prognostic unfavorable (2.93e-5)" "unprognostic (8.14e-2)" "unprognostic (8.24e-2)" "unprognostic (3.15e-1)" "unprognostic (2.09e-3)" 11.1 14.0 6.8 2.0 6.9 3.5 11.1 7.3 11.5 14.2 8.6 13.6 1.9 9.5 3.0 11.2 11.7 1.3 12.7 6.8 7.0 15.4 19.0 15.4 2.9 6.8 6.9 11.0 11.2 2.2 15.1 1.7 6.9 16.2 1.7 3.6 10.4 2.7 10.9 13.0 13.9 1.8 6.7 21.7 10.7 7.0 7.0 2.8 15.3 2.1 2.8 13.1 11.8 7.2 3.8 3.2 2.7 3.7 2.7 0.9 3.0 3.4 3.5 2.9 1.8 19.1 2.4 1.4 10.7 3.8 4.5 9.8 1.3 1.8 2.9 5.3 2.2 6.4 6.2 5.5 2.6 2.7 3.5 1.1 1.9 2.9 3.3 3.0 1.7 4.3 1.4 4.8 2.9 6.1 7.0 5.1 3.7 5.6 8.6 9.5 5.5 6.4 4.4 5.6 3.8 2.6 8.6 2.4 0.8 4.3 7.7 2.7 1.9 2.8 13.7 4.0 2.3 3.9 4.0 5.8 2.3 5.3 5.3 0.4 1.3 2.6 2.7 0.9 3.4 4.1 3.6 3.0 2.2 4.2 3.4 2.6 2.1 3.7 0.9 2.6 5.8 1.9 6.8 6.9 7.3 11.5 6.8 7.0 6.8 6.9 6.9 6.7 7.0 7.2 9.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 15.3 12.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 4.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 7.3 1.7 0.0 0.0 0.0 CGB7 CG-beta-a ENSG00000196337 "Chorionic gonadotropin subunit beta 7" P0DN87 19 49054275-49058860 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "prostate: 3.2;skin 1: 3.9" "Group enriched" "Detected in some" 5 "Pancreatic endocrine cells: 16.5;Syncytiotrophoblasts: 58.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.7;HaCaT: 3.1;hTCEpi: 3.2;U-251 MG: 7.5" "HPA038925, HPA038934" Supported Approved Cytosol "Secreted in other tissues" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA038925: AB_2676272, HPA038934: AB_2676277" "unprognostic (9.53e-2)" "unprognostic (1.99e-1)" "unprognostic (1.87e-1)" "unprognostic (3.53e-1)" "unprognostic (4.60e-5)" "unprognostic (2.64e-1)" "unprognostic (2.46e-1)" "unprognostic (8.37e-2)" "unprognostic (2.88e-2)" "unprognostic (4.80e-2)" "unprognostic (8.83e-4)" "unprognostic (1.54e-1)" "unprognostic (3.89e-8)" "unprognostic (1.63e-2)" "unprognostic (1.94e-1)" "unprognostic (2.05e-1)" "unprognostic (9.28e-2)" 0.1 0.1 0.1 0.0 0.0 0.0 0.6 0.1 0.3 1.1 0.2 0.0 0.1 0.1 0.1 2.4 0.6 0.0 0.1 0.2 0.1 0.2 0.0 0.6 0.0 0.1 0.3 0.1 0.7 0.0 1.5 0.4 0.1 3.2 0.0 0.0 1.1 0.4 2.2 3.9 0.0 0.0 0.1 0.1 0.0 1.1 0.1 0.2 0.2 0.1 0.0 1.1 1.8 0.1 2.2 0.3 0.1 1.0 0.0 0.0 2.7 0.3 0.0 0.6 0.8 0.5 1.8 0.0 0.1 0.5 1.2 3.1 0.0 2.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 3.2 0.2 0.4 1.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 1.0 0.0 0.0 1.1 0.6 0.1 0.0 1.5 1.5 0.0 7.5 0.2 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.2 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.2 0.0 0.5 0.0 0.0 0.6 0.1 0.6 1.8 0.0 0.1 0.3 0.4 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 1.2 0.4 0.3 0.0 58.7 0.0 0.0 0.0 0.1 CHSY1 "CSS1, KIAA0990" ENSG00000131873 "Chondroitin sulfate synthase 1" Q86X52 15 101175727-101252048 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 216.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (7.28e-2)" "unprognostic (6.39e-2)" "unprognostic (9.24e-2)" "unprognostic (1.55e-1)" "unprognostic (7.60e-2)" "unprognostic (9.51e-3)" "unprognostic (1.46e-1)" "unprognostic (3.02e-3)" "unprognostic (1.77e-1)" "unprognostic (1.32e-2)" "unprognostic (5.97e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (6.33e-5)" "unprognostic (3.44e-2)" "unprognostic (1.02e-1)" "unprognostic (8.91e-3)" "unprognostic (5.58e-3)" 27.5 18.6 10.3 18.5 9.8 23.0 21.7 9.0 11.8 19.5 14.4 7.7 6.0 17.3 9.5 10.8 14.9 22.7 20.1 9.2 10.3 13.7 10.0 23.6 11.6 14.2 13.8 19.7 7.3 7.4 8.5 46.7 11.9 14.4 8.2 7.0 10.1 11.4 6.5 15.0 7.7 20.0 11.5 13.9 10.4 8.7 12.5 10.5 10.0 7.4 10.3 34.8 14.0 9.8 9.1 11.2 36.8 18.7 18.9 25.0 24.5 21.8 19.2 25.8 26.2 9.7 7.1 22.0 12.7 36.3 16.8 24.7 24.5 27.7 28.2 24.6 12.4 43.4 12.2 11.4 23.3 66.9 42.9 23.2 22.8 22.3 20.1 29.3 30.8 9.7 16.2 216.3 19.7 7.9 9.2 46.3 42.5 17.7 7.9 20.6 36.9 32.8 18.1 17.7 6.4 34.6 23.0 11.1 40.8 29.8 12.6 81.6 26.2 41.9 24.1 20.0 46.5 38.2 94.5 12.7 32.5 62.2 32.0 0.0 1.3 2.9 1.5 0.8 1.7 0.9 0.9 1.6 0.8 1.0 0.5 1.0 4.9 0.7 0.9 0.5 1.8 0.6 10.3 9.8 9.0 11.8 9.2 10.3 14.2 13.8 11.9 11.5 12.5 9.8 55.0 0.0 15.7 27.7 11.4 57.9 20.7 10.1 20.5 10.7 41.9 29.8 9.3 5.7 9.4 16.5 6.2 6.1 14.6 1.6 1.9 5.3 1.2 10.0 33.4 45.8 3.0 12.0 34.2 2.2 28.8 40.0 5.1 13.8 25.9 51.9 60.0 5.4 16.6 38.7 36.1 3.6 10.2 17.8 37.1 2.5 55.0 41.2 26.6 59.0 10.2 9.2 10.3 21.1 24.2 5.5 2.5 47.0 9.3 19.3 1.2 2.4 8.1 7.5 46.0 47.9 53.5 3.9 7.5 10.5 62.5 13.8 15.2 23.0 3.9 10.2 CLDN5 "AWAL, BEC1, CPETRL1, TMVCF" ENSG00000184113 "Claudin 5" O00501 22 19523024-19527545 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 439.7;breast: 420.9;lung: 398.7" "Group enriched" "Detected in many" 10 "Adipocytes: 2644.3;Endothelial cells: 775.2;Hepatic stellate cells: 701.4" "Cancer enriched" "Detected in all" 4 "glioma: 32.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 18.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 18.8" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 85.4;SCLC-21H: 53.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002607 Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002607: " "unprognostic (1.26e-1)" "unprognostic (2.05e-3)" "unprognostic (1.77e-2)" "unprognostic (2.07e-1)" "unprognostic (3.05e-3)" "unprognostic (6.00e-2)" "unprognostic (4.98e-2)" "unprognostic (3.24e-3)" "unprognostic (1.33e-1)" "unprognostic (8.95e-2)" "unprognostic (2.29e-3)" "unprognostic (1.15e-1)" "unprognostic (7.31e-2)" "unprognostic (2.01e-2)" "unprognostic (2.47e-2)" "unprognostic (2.22e-1)" "unprognostic (2.96e-2)" 439.7 16.2 124.1 6.1 101.0 0.3 420.9 111.7 127.4 70.2 205.2 75.9 9.2 86.1 3.0 54.4 83.1 6.5 138.3 93.8 103.3 45.5 16.9 398.7 9.6 124.5 114.0 36.4 20.7 1.5 16.9 12.5 127.8 50.2 3.6 2.0 36.0 3.5 101.6 95.9 71.0 6.4 109.2 44.8 41.4 10.5 160.7 1.8 122.5 14.9 2.2 103.7 75.9 107.4 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.3 0.1 0.1 0.2 1.1 0.0 0.0 0.0 0.0 85.4 0.1 0.7 0.2 0.1 0.0 0.1 0.5 0.2 0.0 0.2 0.9 0.7 0.1 0.0 0.0 53.0 0.3 0.0 0.0 0.0 0.0 0.4 0.2 7.1 0.1 1.1 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.2 18.8 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.3 0.2 4.6 0.2 5.8 0.0 0.1 0.1 0.0 26.9 124.1 101.0 111.7 127.4 93.8 103.3 124.5 114.0 127.8 109.2 160.7 107.4 2644.3 3.2 7.7 0.7 2.4 32.4 1.1 0.1 3.4 1.8 5.9 7.6 14.8 2.8 0.6 7.3 0.0 0.3 4.2 0.0 0.0 0.7 5.0 8.1 0.7 775.2 2.4 8.0 0.0 0.8 0.1 12.5 0.0 1.0 1.3 0.3 701.4 2.7 0.8 0.0 0.1 0.2 4.1 17.0 33.3 5.5 5.3 46.2 14.2 129.3 0.7 2.4 1.0 0.5 0.3 0.0 0.0 0.7 2.8 4.0 0.0 0.0 0.3 7.3 0.0 61.7 12.1 1.1 1.9 1.2 30.5 0.0 4.6 25.0 0.0 6.7 CLEC14A C14orf27 ENSG00000176435 "C-type lectin domain containing 14A" Q86T13 14 38254000-38256093 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 13 "Adipocytes: 396.6;Endothelial cells: 272.8;Hepatic stellate cells: 567.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 83.7;HUVEC TERT2: 451.8;TIME: 158.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039468, HPA048119" Uncertain Supported "Endoplasmic reticulum,Golgi apparatus" NA NA 4100000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum, Golgi apparatus" "HPA039468: AB_2676524, HPA048119: AB_2680270" "unprognostic (4.02e-1)" "unprognostic (4.26e-2)" "unprognostic (4.20e-3)" "unprognostic (9.44e-2)" "unprognostic (1.35e-1)" "prognostic favorable (4.13e-6)" "unprognostic (2.55e-3)" "unprognostic (2.69e-1)" "unprognostic (1.67e-1)" "unprognostic (6.90e-2)" "unprognostic (5.41e-2)" "unprognostic (1.26e-1)" "unprognostic (1.63e-2)" "unprognostic (1.75e-2)" "unprognostic (1.55e-1)" "unprognostic (4.97e-2)" "unprognostic (5.28e-2)" 67.1 9.5 13.6 7.9 13.4 0.1 50.6 13.8 15.2 24.8 10.9 15.2 10.1 31.2 7.6 11.1 22.6 19.0 65.1 11.5 13.3 15.9 9.4 55.5 6.6 15.0 13.9 9.5 7.8 10.5 6.1 25.0 15.4 14.5 7.2 0.8 13.6 9.8 33.2 15.8 18.8 19.8 13.1 16.7 13.8 3.5 14.9 4.6 31.4 43.3 4.2 19.2 16.8 15.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 451.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 158.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 13.4 13.8 15.2 11.5 13.3 15.0 13.9 15.4 13.1 14.9 15.6 396.6 0.0 3.2 0.0 0.9 3.4 0.2 0.0 1.8 0.1 1.5 2.5 6.4 1.5 0.6 0.0 0.0 0.1 0.2 0.0 0.0 0.1 1.1 0.2 0.5 272.8 0.0 0.0 0.4 0.2 0.1 31.0 0.0 0.3 1.3 0.1 567.2 2.1 0.4 0.0 0.2 0.0 0.0 6.4 3.1 1.0 0.6 1.1 5.4 15.0 0.0 0.2 0.0 4.0 2.9 0.0 0.0 0.4 1.4 0.2 0.0 0.0 0.0 0.5 0.0 14.1 7.5 1.6 0.9 0.9 3.1 0.1 1.3 6.7 0.0 0.3 CLIC2 "CLCNL2, XAP121" ENSG00000155962 "Chloride intracellular channel 2" O15247 X 155276211-155334657 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 51.2;Alveolar cells type 1: 89.8;Alveolar cells type 2: 54.9;Endothelial cells: 60.4;Erythroid cells: 70.7;Kupffer cells: 73.5;Langerhans cells: 135.0;monocytes: 71.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 18.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 18.6;myeloid DC: 47.9;non-classical monocyte: 14.2" "Group enriched" "Detected in many" 16 "dendritic cells: 47.9;monocytes: 18.6" "Group enriched" "Detected in some" 5 "HDLM-2: 103.3;K-562: 60.4;Karpas-707: 53.4;RPMI-8226: 92.2" "Low region specificity" "Detected in all" "HPA047381, HPA060101" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 150000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" Nucleoplasm "HPA047381: AB_2680022, HPA060101: AB_2684204" "unprognostic (3.27e-2)" "unprognostic (5.21e-3)" "unprognostic (9.70e-2)" "unprognostic (7.25e-2)" "unprognostic (9.71e-2)" "unprognostic (3.78e-2)" "unprognostic (1.46e-1)" "unprognostic (4.07e-2)" "unprognostic (2.95e-1)" "unprognostic (1.74e-1)" "unprognostic (1.97e-1)" "unprognostic (3.31e-1)" "prognostic unfavorable (1.74e-5)" "unprognostic (1.97e-2)" "unprognostic (2.97e-2)" "unprognostic (6.63e-2)" "unprognostic (1.54e-1)" 23.1 7.1 6.9 16.7 7.8 9.8 16.7 6.9 18.1 20.1 7.6 10.9 8.7 22.6 7.8 9.4 12.5 19.0 14.6 7.1 7.0 5.8 12.8 30.6 30.2 7.7 6.9 21.6 3.5 4.6 4.5 9.3 7.4 4.6 13.6 2.4 6.2 6.3 4.4 6.1 10.3 17.7 7.7 50.1 8.5 3.2 8.5 14.5 31.8 14.3 25.6 15.9 10.7 7.8 0.7 0.0 1.0 0.9 1.0 4.7 0.0 0.2 2.8 0.0 0.4 0.0 0.2 0.1 0.4 0.0 0.2 0.1 0.3 0.0 0.0 103.3 0.5 16.4 0.3 0.0 0.0 0.4 0.6 1.4 0.0 0.0 0.1 0.5 0.1 0.5 60.4 53.4 0.3 0.2 0.1 1.3 0.2 0.1 0.4 0.4 0.0 92.2 0.2 0.2 0.7 0.9 0.0 0.1 0.4 0.2 0.0 1.0 0.0 5.3 1.6 2.0 0.9 3.3 4.6 0.0 2.7 2.6 1.7 0.0 3.5 0.2 0.0 18.6 0.3 0.0 0.1 0.1 47.9 0.0 0.0 0.0 1.4 2.0 14.2 5.2 0.0 2.1 6.9 7.8 6.9 18.1 7.1 7.0 7.7 6.9 7.4 7.7 8.5 7.8 51.2 89.8 54.9 3.9 1.1 13.3 0.8 0.2 2.2 1.2 0.7 1.3 3.2 0.0 5.8 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.5 11.3 60.4 1.2 70.7 8.6 0.2 0.1 25.6 0.5 0.4 3.8 0.5 27.1 1.2 4.7 0.0 7.0 0.6 0.0 73.5 135.0 1.1 13.7 34.5 17.8 8.4 71.4 0.2 0.0 3.0 2.4 0.1 0.0 9.4 2.0 0.5 0.0 0.6 1.5 0.3 6.6 2.5 4.6 0.3 0.3 0.4 13.8 0.0 2.6 5.2 0.1 1.9 CNN3 ENSG00000117519 "Calponin 3" Q15417 1 94896949-94927223 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "glioma: 315.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 10.5;naive CD4 T-cell: 11.6" "Group enriched" "Detected in many" 12 "B-cells: 10.5;T-cells: 11.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009849, HPA051237" Enhanced Enhanced "Actin filaments,Cytosol" NA NA 660000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" Cytosol "CAB009849: AB_2276410, HPA051237: AB_2681399" "unprognostic (8.47e-2)" "unprognostic (5.19e-2)" "unprognostic (5.22e-2)" "unprognostic (3.91e-1)" "unprognostic (1.47e-1)" "unprognostic (2.85e-2)" "unprognostic (8.87e-2)" "unprognostic (5.20e-2)" "unprognostic (2.32e-1)" "unprognostic (1.34e-1)" "unprognostic (1.52e-1)" "unprognostic (2.37e-1)" "unprognostic (3.77e-3)" "unprognostic (2.33e-2)" "unprognostic (8.71e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (1.99e-4)" 163.9 255.6 152.7 78.9 153.7 2.1 160.0 148.6 186.3 164.8 147.7 142.4 135.9 214.0 71.0 149.7 147.1 152.3 127.6 151.7 189.9 245.1 143.7 209.0 51.4 197.4 170.9 153.1 83.3 53.1 101.7 256.0 173.1 126.2 82.8 125.0 125.5 133.7 26.3 62.5 100.0 196.0 180.8 94.1 111.8 50.2 164.5 55.1 125.0 52.6 44.3 156.5 166.2 174.0 416.6 77.9 429.0 380.1 286.0 264.2 191.7 197.2 381.3 319.4 511.2 348.7 35.6 0.1 436.6 243.4 315.7 116.2 307.2 169.9 428.1 1.6 113.0 18.8 47.5 256.2 545.0 0.2 0.8 246.2 25.5 394.1 89.4 539.6 282.8 26.7 4.1 35.3 798.9 0.2 19.8 0.9 333.6 0.3 43.3 0.6 524.2 1.8 392.9 156.6 26.3 264.2 163.0 65.0 272.8 301.7 124.8 38.5 182.4 212.2 364.9 80.2 647.0 43.9 27.2 1.5 46.0 0.6 327.1 0.2 0.0 0.0 2.2 0.1 3.4 4.6 2.1 1.2 0.1 10.5 11.6 8.3 0.4 0.9 0.1 0.0 0.0 2.6 152.7 153.7 148.6 186.3 151.7 189.9 197.4 170.9 173.1 180.8 164.5 174.0 183.5 150.6 80.7 82.9 18.1 78.3 435.7 232.3 48.9 11.9 122.2 64.1 42.2 88.6 156.2 126.9 20.9 236.1 3.2 36.0 436.3 275.1 156.1 77.4 151.1 278.3 72.4 20.0 12.9 240.7 40.9 287.8 33.1 104.9 14.0 164.4 373.0 152.1 22.6 1.7 16.9 58.7 429.3 20.1 56.3 150.7 274.6 9.3 197.5 29.0 4.7 394.6 0.0 62.4 22.7 130.8 53.2 382.1 2.6 319.1 117.9 518.5 95.1 14.4 263.0 399.8 374.9 10.8 34.7 91.4 77.7 205.8 14.9 214.5 131.0 327.4 COL7A1 "EBD1, EBDCT, EBR1" ENSG00000114270 "Collagen type VII alpha 1 chain" Q02388 3 48564073-48595329 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 98.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 72.5;Basal respiratory cells: 59.3;Basal squamous epithelial cells: 67.2;Endometrial stromal cells: 45.3" "Cancer enhanced" "Detected in all" "head and neck cancer: 41.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 65.7;HaCaT: 63.5;HBEC3-KT: 100.6;HDLM-2: 97.8;HeLa: 146.2;SiHa: 82.8" "CAB016357, HPA018877, HPA042420" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 6000 "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" Vesicles "CAB016357: AB_2229746, HPA018877: , HPA042420: AB_2677990" "unprognostic (2.69e-2)" "unprognostic (4.11e-1)" "unprognostic (1.35e-1)" "unprognostic (3.47e-1)" "unprognostic (4.93e-2)" "prognostic favorable (6.31e-4)" "unprognostic (7.56e-2)" "unprognostic (1.25e-2)" "unprognostic (5.59e-2)" "unprognostic (2.98e-1)" "prognostic unfavorable (3.86e-4)" "unprognostic (3.74e-2)" "unprognostic (0.00e+0)" "unprognostic (1.76e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-1)" "unprognostic (3.86e-2)" 0.8 1.1 1.4 3.8 1.0 0.1 4.9 2.8 2.1 24.3 0.4 2.9 1.7 12.1 6.7 21.8 6.4 4.0 3.2 0.3 6.5 7.4 1.3 1.7 1.2 7.0 3.2 3.4 0.4 0.0 2.5 1.6 3.0 34.2 0.9 1.4 11.5 12.2 3.5 98.2 4.1 2.5 2.6 6.5 2.1 3.6 6.5 1.2 0.5 0.6 1.3 6.6 29.2 0.6 0.2 25.4 1.2 0.5 9.2 12.3 31.0 65.7 40.8 16.9 10.0 0.4 0.5 0.1 2.0 15.0 15.4 63.5 0.0 100.6 3.1 97.8 0.5 0.2 146.2 4.3 25.6 0.0 0.4 19.9 58.8 34.4 26.8 23.1 0.0 0.7 0.5 0.7 2.0 0.3 0.0 0.9 3.1 1.3 1.3 0.5 2.2 0.2 9.2 0.2 0.2 0.2 82.8 0.1 0.8 3.7 1.3 0.3 0.0 5.6 3.2 3.2 50.1 1.8 1.8 0.1 49.0 0.4 2.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.0 2.8 2.1 0.3 6.5 7.0 3.2 3.0 2.6 6.5 0.6 0.4 0.0 0.0 10.7 0.2 72.5 24.1 59.3 67.2 17.7 1.0 10.2 6.6 0.0 10.6 11.0 10.4 1.4 0.1 0.6 0.0 0.9 11.8 3.1 45.3 1.4 1.8 0.0 6.8 0.7 1.0 8.3 1.1 4.0 0.0 0.8 0.4 0.7 1.6 8.4 11.6 0.7 0.0 0.3 4.2 6.3 5.0 0.8 8.8 8.4 0.1 2.6 0.0 4.0 4.4 15.6 0.1 5.7 0.0 5.7 0.2 0.3 2.5 12.9 0.0 2.0 13.4 2.6 1.5 11.3 24.2 1.2 0.8 5.0 0.2 5.8 CORO2B "ClipinC, KIAA0925" ENSG00000103647 "Coronin 2B" Q9UQ03 15 68578993-68727806 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 83.4;retina: 45.2" "Cell type enhanced" "Detected in many" "Astrocytes: 57.1;Bipolar cells: 43.2;Cone photoreceptor cells: 37.5;Excitatory neurons: 96.6;Inhibitory neurons: 50.0;Oligodendrocytes: 146.4" "Group enriched" "Detected in many" 8 "glioma: 34.7;melanoma: 21.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.2" "Lineage enriched" "Detected in single" 13 "B-cells: 1.2" "Cell line enhanced" "Detected in many" "ASC diff: 26.8;ASC TERT1: 57.5;HSkMC: 41.6;hTEC/SVTERT24-B: 34.6;U-87 MG: 59.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017960 Enhanced Supported Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 37: B-cells - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Focal adhesion sites" "HPA017960: AB_1847167" "unprognostic (1.35e-1)" "unprognostic (2.63e-2)" "unprognostic (2.81e-3)" "unprognostic (4.71e-3)" "unprognostic (3.28e-1)" "unprognostic (8.11e-5)" "unprognostic (4.77e-2)" "unprognostic (1.24e-1)" "unprognostic (3.68e-2)" "unprognostic (1.81e-1)" "unprognostic (1.33e-3)" "unprognostic (4.12e-2)" "unprognostic (1.26e-1)" "unprognostic (1.10e-2)" "unprognostic (5.83e-2)" "unprognostic (3.59e-2)" "unprognostic (1.87e-2)" 10.9 3.5 44.1 2.0 60.9 0.7 7.2 62.1 66.5 7.2 28.2 5.9 1.2 7.5 2.2 1.4 27.5 4.7 16.4 48.1 43.5 9.2 1.3 5.1 1.8 62.4 62.7 14.9 2.2 0.5 3.5 3.2 58.0 4.3 1.5 45.2 2.7 4.9 2.6 4.1 2.8 6.3 51.9 3.9 3.1 1.0 66.5 1.3 6.1 4.5 0.8 4.1 3.7 83.4 0.6 0.8 26.2 2.2 26.8 57.5 0.0 13.7 15.0 2.3 3.2 0.3 3.0 3.5 1.6 2.3 3.7 0.2 1.0 0.3 9.5 0.0 1.2 0.0 0.0 1.2 9.8 0.0 0.4 41.6 0.3 34.6 2.0 20.4 1.0 0.0 0.0 0.1 24.4 0.1 0.0 0.1 6.5 0.0 0.1 2.2 0.1 1.2 3.7 0.0 15.3 0.3 0.2 0.0 7.8 4.8 0.0 3.1 0.2 7.8 8.9 1.7 18.3 0.0 0.0 3.5 59.2 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.1 60.9 62.1 66.5 48.1 43.5 62.4 62.7 58.0 51.9 66.5 83.4 2.8 0.0 0.0 57.1 1.1 1.0 0.4 0.0 0.0 43.2 0.1 1.0 1.5 0.0 0.0 7.3 37.5 0.0 0.0 0.0 0.0 3.8 0.4 2.1 11.6 3.0 3.6 0.0 96.6 0.6 0.0 8.0 0.0 0.3 0.0 0.9 6.4 0.0 0.2 0.0 50.0 0.3 0.0 0.3 0.7 0.7 7.8 0.3 7.2 11.2 0.1 12.5 0.0 17.1 146.4 0.6 0.0 0.4 0.0 0.1 0.0 0.1 8.1 21.4 6.6 1.4 2.1 0.2 0.5 0.1 0.9 0.0 0.1 7.5 0.0 0.1 CPNE8 ENSG00000139117 "Copine 8" Q86YQ8 12 38646822-38907430 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 115.5;Microglial cells: 77.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 66.8;THP-1: 38.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA038600 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA038600: AB_10674690" "unprognostic (1.57e-1)" "unprognostic (3.07e-1)" "unprognostic (3.38e-1)" "unprognostic (3.78e-3)" "unprognostic (8.93e-3)" "unprognostic (6.28e-3)" "unprognostic (6.74e-2)" "unprognostic (8.44e-2)" "unprognostic (5.40e-3)" "unprognostic (4.29e-1)" "unprognostic (1.28e-2)" "unprognostic (2.27e-1)" "unprognostic (2.64e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (3.21e-1)" "unprognostic (5.13e-2)" "unprognostic (8.73e-3)" 12.0 8.3 7.0 5.4 7.6 4.6 9.6 3.1 11.5 7.8 9.2 8.1 3.3 5.1 3.5 5.4 5.0 9.0 12.2 10.1 8.9 11.2 15.5 10.1 5.4 5.0 6.5 5.7 3.2 2.5 3.3 12.0 4.6 3.7 10.2 6.0 3.2 8.9 2.9 6.1 4.6 9.1 8.8 10.6 3.7 5.8 8.0 3.1 7.8 5.3 3.2 10.1 5.3 5.5 3.1 18.7 1.3 18.5 17.0 14.3 8.6 1.6 0.1 0.0 0.0 9.4 18.2 0.0 26.3 12.7 6.8 1.0 10.8 5.6 0.0 0.0 11.3 9.9 26.3 2.2 11.3 0.0 7.8 6.7 14.2 4.2 14.9 12.9 14.3 0.0 6.0 0.0 0.0 0.0 0.0 0.1 13.8 11.5 19.0 0.0 0.0 4.3 66.8 0.5 0.0 0.5 26.0 4.7 14.1 18.8 2.3 38.8 13.6 0.0 12.7 21.6 0.1 6.5 19.3 0.2 17.2 17.8 11.0 2.7 12.0 0.0 1.6 9.4 0.3 0.2 2.1 1.8 7.7 0.6 0.9 1.5 0.7 4.5 6.3 2.5 2.1 2.5 7.0 7.6 3.1 11.5 10.1 8.9 5.0 6.5 4.6 8.8 8.0 5.5 68.8 12.8 8.2 66.3 1.6 31.1 5.9 40.8 19.9 2.1 0.6 6.5 20.3 15.7 23.3 12.9 0.0 29.2 6.9 35.8 15.6 7.6 68.9 2.7 9.4 55.9 11.5 7.4 115.5 4.9 27.2 27.1 0.0 3.0 3.8 18.5 36.0 16.5 25.7 0.0 36.3 9.1 6.1 34.1 42.4 14.5 9.6 19.4 46.2 77.8 19.8 36.4 2.1 25.6 2.9 3.6 51.3 8.2 3.3 7.4 0.0 20.9 17.0 2.7 0.0 24.5 16.9 2.7 2.1 6.1 11.2 7.8 4.3 8.6 8.9 3.5 CREG2 ENSG00000175874 "Cellular repressor of E1A stimulated genes 2" Q8IUH2 2 101345550-101387503 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "brain: 27.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 66.0;Inhibitory neurons: 27.6;Oligodendrocytes: 12.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 12 "amygdala: 8.7;basal ganglia: 17.2;cerebral cortex: 26.3;hippocampal formation: 27.8;white matter: 9.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 2.5;HaCaT: 6.3;HeLa: 2.5;OE19: 7.1;PC-3: 2.4;RT4: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA038224 Enhanced "Secreted in brain" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 10: Brain - Neuronal signaling" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA038224: AB_10673167" "unprognostic (5.09e-2)" "unprognostic (3.78e-3)" "unprognostic (4.10e-3)" "unprognostic (8.15e-3)" "unprognostic (5.63e-3)" "unprognostic (9.68e-3)" "unprognostic (4.52e-8)" "unprognostic (3.86e-4)" "unprognostic (1.39e-1)" "unprognostic (6.49e-2)" "unprognostic (1.90e-2)" "unprognostic (7.69e-2)" "unprognostic (5.41e-3)" "unprognostic (4.44e-2)" "unprognostic (2.91e-1)" "unprognostic (8.26e-3)" "unprognostic (7.77e-2)" 0.0 0.1 8.7 0.0 17.2 0.1 0.0 0.0 26.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.1 27.8 0.0 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.2 0.2 0.0 0.6 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.1 0.7 9.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 1.4 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.1 2.4 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 8.7 17.2 0.0 26.3 27.8 0.0 1.3 0.0 0.6 0.0 1.4 9.0 0.0 0.0 0.0 2.9 0.0 0.0 0.6 0.5 0.0 0.8 0.1 0.1 0.9 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.2 0.0 0.5 0.0 0.0 66.0 0.2 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 27.6 0.1 2.0 0.0 0.0 6.5 0.0 0.2 0.0 6.5 0.0 0.8 0.0 2.5 12.0 2.8 0.0 0.0 0.0 0.3 0.0 0.0 0.8 0.5 0.0 0.2 0.1 1.5 5.6 0.5 0.0 0.1 0.0 0.2 0.0 1.5 CYYR1 C21orf95 ENSG00000166265 "Cysteine and tyrosine rich 1" Q96J86 21 26466209-26573286 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 200.0;Endothelial cells: 150.0;Hepatic stellate cells: 79.9;Microglial cells: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 38 "plasmacytoid DC: 31.4" "Lineage enriched" "Detected in single" 82 "dendritic cells: 31.4" "Cell line enhanced" "Detected in some" "AF22: 14.1;NTERA-2: 39.2;PC-3: 11.0;RH-30: 16.6;SCLC-21H: 33.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034921, HPA067685" Uncertain Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB034921: AB_2089315, HPA067685: AB_2685887" "unprognostic (5.64e-2)" "unprognostic (2.59e-2)" "unprognostic (1.37e-1)" "unprognostic (1.88e-1)" "unprognostic (7.00e-2)" "unprognostic (2.63e-2)" "unprognostic (2.88e-3)" "unprognostic (4.04e-1)" "unprognostic (1.11e-2)" "unprognostic (1.12e-1)" "unprognostic (3.77e-2)" "unprognostic (1.46e-1)" "unprognostic (2.44e-3)" "unprognostic (9.29e-3)" "unprognostic (2.26e-1)" "unprognostic (1.88e-1)" "unprognostic (1.49e-2)" 36.4 46.4 9.7 8.1 9.0 7.8 30.2 8.7 11.4 16.4 8.4 8.4 6.1 19.2 8.1 9.0 12.9 16.1 22.3 8.1 9.4 12.7 4.8 23.7 6.0 9.9 10.5 4.5 5.5 15.5 3.8 36.3 10.6 9.5 6.6 0.9 6.8 11.4 15.1 8.2 9.6 23.6 9.6 32.5 7.7 1.9 10.8 6.0 14.1 31.8 4.6 12.6 9.5 9.4 0.0 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 7.1 1.6 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 6.5 0.0 0.4 0.0 5.6 0.0 0.0 0.0 2.6 0.0 0.0 0.1 39.2 0.0 11.0 0.0 16.6 0.0 1.7 0.0 33.7 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 3.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 31.4 0.0 0.1 9.7 9.0 8.7 11.4 8.1 9.4 9.9 10.5 10.6 9.6 10.8 9.4 200.0 0.0 0.6 1.6 1.5 11.7 2.0 10.2 27.3 0.1 14.9 15.0 6.7 0.0 1.7 14.7 0.0 0.1 14.9 0.0 3.9 0.0 0.7 0.4 6.9 150.0 0.0 11.1 1.6 0.0 0.2 8.3 0.0 0.4 0.0 3.7 79.9 0.4 0.3 0.0 4.6 0.0 2.0 3.2 8.0 1.5 2.1 1.4 7.2 58.1 0.7 0.5 0.0 0.0 0.7 0.1 0.0 0.0 2.5 1.1 0.0 6.8 1.1 0.3 0.0 13.3 4.4 0.2 1.3 4.9 5.4 0.3 1.5 0.4 0.0 0.7 DBF4 "ASK, chif, DBF4A, ZDBF1" ENSG00000006634 "DBF4 zinc finger" Q9UBU7 7 87876216-87909553 "Predicted intracellular proteins" "Cell cycle, DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 20 "testis: 15.1" "Group enriched" "Detected in all" 4 "Early spermatids: 468.6;Spermatocytes: 569.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042923 Supported "Nucleoplasm,Nuclear bodies" Yes Yes "Cluster 10: Basophils - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "HPA042923: AB_2678222" "unprognostic (2.48e-1)" "unprognostic (8.32e-2)" "unprognostic (1.15e-2)" "unprognostic (4.86e-3)" "unprognostic (2.81e-2)" "unprognostic (3.63e-1)" "prognostic unfavorable (4.45e-6)" "unprognostic (1.05e-1)" "prognostic unfavorable (6.86e-4)" "unprognostic (1.46e-3)" "unprognostic (1.05e-3)" "unprognostic (2.78e-3)" "prognostic unfavorable (6.42e-7)" "unprognostic (1.98e-2)" "unprognostic (2.40e-1)" "unprognostic (1.47e-1)" "unprognostic (1.30e-1)" 0.1 0.2 0.2 0.2 0.4 0.6 0.2 0.7 0.4 0.2 0.1 0.2 0.2 0.2 0.3 0.1 0.1 0.4 0.1 0.2 0.1 0.2 0.2 0.1 0.5 0.2 0.2 0.2 0.1 0.1 0.0 0.1 0.2 0.2 0.2 0.2 0.1 0.1 0.1 0.2 0.3 0.0 0.1 0.3 0.2 15.1 0.2 0.6 0.3 0.0 0.5 0.1 0.1 0.3 0.9 0.8 2.0 2.5 0.4 0.4 0.5 1.0 0.2 1.0 2.1 1.4 0.6 2.1 0.6 0.6 1.7 0.9 2.2 0.5 1.0 1.6 1.3 1.3 1.0 0.4 0.1 1.7 1.0 0.4 0.6 1.2 1.0 0.3 0.9 1.9 1.2 4.2 1.4 1.7 2.8 2.0 2.0 2.1 1.9 0.7 3.1 2.5 0.8 0.1 3.0 1.8 1.2 2.2 1.0 1.6 0.9 1.6 0.1 1.2 1.4 3.1 2.0 2.3 5.2 2.1 0.8 3.1 2.5 1.0 0.1 0.1 0.3 0.0 0.1 0.2 0.2 0.1 0.0 0.2 0.2 0.3 0.2 0.2 0.0 0.2 0.4 0.1 0.2 0.4 0.7 0.4 0.2 0.1 0.2 0.2 0.2 0.1 0.2 0.3 13.3 3.2 12.6 5.5 38.4 15.6 16.4 10.7 12.0 6.6 13.0 16.8 3.7 2.8 7.7 9.2 12.5 19.6 59.2 9.7 3.9 8.3 468.6 12.1 23.6 11.1 14.9 40.8 14.7 14.7 36.4 12.4 14.3 17.7 31.0 19.4 6.4 6.5 16.1 3.3 9.1 20.6 16.2 9.1 15.5 116.0 15.5 20.8 12.4 2.8 11.0 2.1 24.7 6.0 6.7 14.1 8.5 9.4 48.9 18.4 4.2 5.8 10.2 16.6 13.1 9.7 11.4 569.4 74.6 20.5 12.6 9.6 44.4 13.5 22.3 11.7 DENND2C "dJ1156J9.1, DKFZp686G0351, DKFZp779P1149, FLJ37099, RP5-1156J9.1" ENSG00000175984 "DENN domain containing 2C" Q68D51 1 114582848-114670422 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 17.7;skeletal muscle: 41.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 109.1;Basal prostatic cells: 138.2;Glandular and luminal cells: 192.7;Squamous epithelial cells: 114.9;Suprabasal keratinocytes: 171.8;Urothelial cells: 340.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "basophil: 3.0" "Lineage enriched" "Detected in single" 12 "granulocytes: 3.0" "Cell line enhanced" "Detected in many" "U-2197: 11.8;U-266/70: 25.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA029935, HPA054955" Uncertain Enhanced Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 59: Non-specific - Translation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA029935: AB_10601208, HPA054955: AB_2682648" "unprognostic (2.25e-1)" "unprognostic (1.08e-1)" "unprognostic (9.97e-2)" "unprognostic (4.89e-4)" "unprognostic (1.52e-1)" "unprognostic (2.46e-1)" "unprognostic (2.53e-1)" "unprognostic (3.18e-1)" "unprognostic (1.26e-1)" "unprognostic (6.61e-2)" "unprognostic (2.20e-2)" "unprognostic (7.43e-2)" "unprognostic (2.77e-2)" "unprognostic (2.24e-2)" "unprognostic (6.11e-2)" "unprognostic (3.64e-2)" "unprognostic (1.57e-2)" 0.9 0.5 0.8 0.3 0.8 1.0 1.9 0.9 0.9 4.2 2.2 0.6 0.7 1.5 0.8 17.7 0.9 1.2 1.1 1.1 0.4 0.6 2.0 1.5 0.4 0.6 0.6 1.1 1.2 1.7 0.6 0.1 0.7 1.4 0.6 1.5 2.7 1.4 41.6 12.4 0.6 1.1 0.3 0.4 0.9 5.5 0.6 0.4 1.4 1.7 3.4 2.6 7.0 0.5 2.1 0.0 0.1 1.4 1.7 1.8 0.4 0.6 1.1 0.7 1.1 0.3 0.0 0.1 0.9 4.1 1.4 7.4 1.4 4.6 0.7 0.1 1.8 1.2 0.4 0.1 0.5 0.0 1.8 1.8 4.4 2.7 2.3 0.1 0.2 0.5 0.2 0.3 2.4 6.0 0.2 0.1 0.9 0.0 1.1 0.0 6.2 0.1 0.1 5.7 0.0 0.0 4.5 0.1 0.5 1.1 0.9 0.3 0.3 1.0 1.5 11.8 0.2 25.4 4.8 0.0 1.0 0.0 0.8 3.0 0.0 0.9 0.1 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.1 0.8 0.8 0.9 0.9 1.1 0.4 0.6 0.6 0.7 0.3 0.6 0.5 6.6 28.9 2.2 3.3 3.3 109.1 138.2 32.5 60.3 20.4 5.2 5.3 8.7 11.5 21.3 7.3 20.9 0.1 1.9 1.1 0.0 7.2 29.5 100.3 15.7 8.6 0.0 0.0 2.8 7.5 0.1 6.9 5.6 192.7 2.5 8.1 15.4 11.7 0.3 0.0 0.8 0.9 4.1 2.2 9.3 12.9 5.0 14.0 7.2 9.4 1.1 2.3 1.0 5.0 3.5 33.0 0.2 2.2 17.6 79.5 0.1 0.8 46.8 10.3 0.0 21.7 6.6 47.9 59.7 114.9 171.8 0.0 3.7 1.3 1.5 340.4 DIPK2B "CXorf36, DIA1R, FLJ14103" ENSG00000147113 "Divergent protein kinase domain 2B" Q9H7Y0 X 45148373-45200901 "Disease related genes, Predicted secreted proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Adipocytes: 96.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 57 "HUVEC TERT2: 81.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002806 Uncertain "Secreted - unknown location" NA NA 940000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA002806: AB_1078595" "unprognostic (2.12e-1)" "unprognostic (1.32e-2)" "unprognostic (8.51e-3)" "unprognostic (2.05e-1)" "unprognostic (4.65e-2)" "unprognostic (4.07e-3)" "unprognostic (7.30e-2)" "unprognostic (1.61e-1)" "unprognostic (1.50e-1)" "unprognostic (3.39e-1)" "unprognostic (6.06e-2)" "unprognostic (1.32e-1)" "unprognostic (1.75e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (8.47e-2)" "unprognostic (3.11e-2)" 40.8 5.3 14.4 6.1 15.0 0.8 36.9 11.7 13.9 19.6 7.8 9.1 2.6 20.5 6.9 6.5 18.0 8.8 27.3 11.4 13.1 7.0 1.4 14.1 5.7 14.4 14.2 6.9 3.5 4.6 3.3 40.5 14.1 11.3 3.8 1.4 6.8 7.2 16.6 7.4 7.7 20.7 12.4 3.1 6.3 1.5 14.8 2.7 18.5 16.6 3.4 14.3 13.9 15.4 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 81.7 0.1 0.0 0.5 0.0 0.1 0.0 0.3 0.1 1.4 0.5 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.5 0.1 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 14.4 15.0 11.7 13.9 11.4 13.1 14.4 14.2 14.1 12.4 14.8 15.4 96.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 DNAH17 "DNAHL1, DNEL2, FLJ40457" ENSG00000187775 "Dynein axonemal heavy chain 17" Q9UFH2 17 78423697-78577396 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 2.1;retina: 2.5;testis: 5.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 56.4;Cone photoreceptor cells: 87.6;Early spermatids: 43.7;Late spermatids: 36.6;Oligodendrocytes: 52.5" "Group enriched" "Detected in some" 4 "head and neck cancer: 2.9;lung cancer: 1.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HeLa: 5.7;MOLT-4: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA024354, HPA076261" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Plasma membrane" Cytosol "HPA024354: AB_1847911, HPA076261: AB_2732305" "unprognostic (4.98e-4)" "unprognostic (2.26e-1)" "unprognostic (2.30e-3)" "unprognostic (8.70e-3)" "unprognostic (6.66e-2)" "unprognostic (9.23e-2)" "unprognostic (3.72e-3)" "unprognostic (8.41e-2)" "unprognostic (2.66e-1)" "unprognostic (1.11e-1)" "unprognostic (1.20e-3)" "unprognostic (8.35e-3)" "unprognostic (1.58e-10)" "unprognostic (5.25e-2)" "unprognostic (1.54e-1)" "unprognostic (5.12e-1)" "unprognostic (6.04e-3)" 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 1.6 0.8 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 2.5 0.0 0.0 0.0 0.4 0.0 0.0 0.9 0.0 0.0 5.5 0.6 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 5.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.2 0.0 0.2 1.6 0.8 1.3 0.9 0.6 2.1 0.4 6.4 0.5 0.7 0.6 0.6 0.3 0.1 0.0 56.4 0.1 0.0 2.5 0.0 0.0 0.0 87.6 0.0 0.1 0.0 0.0 0.0 43.7 1.4 0.5 1.0 0.0 0.0 2.2 0.0 0.0 0.3 0.0 1.7 0.0 0.1 0.0 0.0 0.1 0.0 2.1 0.0 0.0 0.8 1.7 36.6 0.6 2.9 0.0 1.0 0.1 1.5 0.0 1.0 52.5 0.1 0.0 0.4 0.4 0.3 0.0 0.1 0.0 7.8 0.0 0.6 0.5 17.4 0.6 0.0 0.1 0.0 0.3 0.4 0.0 0.1 DOCK4 "FLJ34238, KIAA0716" ENSG00000128512 "Dedicator of cytokinesis 4" Q8N1I0 7 111726110-112206407 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.6" "Group enriched" "Detected in many" 4 "Astrocytes: 791.0;Excitatory neurons: 422.8;Microglial cells: 1568.3;Oligodendrocyte precursor cells: 434.3;Oligodendrocytes: 815.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.7" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 43.3;HUVEC TERT2: 75.5;TIME: 69.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071516 Approved "Nucleoli,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 65: Brain - Ion transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Plasma membrane" "Golgi apparatus, Cytosol" "HPA071516: AB_2686407" "unprognostic (1.37e-1)" "unprognostic (4.18e-1)" "unprognostic (1.53e-1)" "unprognostic (2.48e-2)" "unprognostic (7.10e-2)" "unprognostic (2.03e-2)" "unprognostic (9.10e-2)" "unprognostic (2.18e-2)" "unprognostic (3.03e-2)" "unprognostic (5.78e-2)" "unprognostic (7.06e-2)" "unprognostic (3.66e-1)" "unprognostic (5.71e-2)" "unprognostic (1.89e-2)" "unprognostic (9.48e-2)" "unprognostic (4.39e-2)" "unprognostic (2.39e-2)" 7.8 4.4 17.1 6.6 41.6 1.4 4.8 11.4 21.9 5.0 0.0 3.2 1.5 4.6 2.8 2.5 5.2 5.0 4.9 40.6 17.8 4.5 10.0 17.3 2.7 16.5 18.1 8.4 3.2 3.3 3.2 6.9 15.6 4.0 2.8 10.5 3.3 2.5 6.2 2.5 2.4 7.3 14.9 1.8 2.2 2.1 19.2 1.7 3.5 7.3 2.2 3.7 3.5 26.0 0.1 3.5 8.8 7.8 7.2 10.4 5.3 1.0 9.6 1.7 2.8 0.0 0.2 0.8 7.6 2.3 2.0 0.5 1.5 8.8 6.5 2.9 12.9 0.4 5.8 14.3 5.1 1.1 0.4 4.9 1.0 43.3 20.8 3.0 75.5 3.4 0.1 22.6 3.8 1.0 2.0 0.7 5.1 1.5 15.8 0.8 7.0 3.6 6.0 0.5 1.9 7.5 6.2 4.3 5.8 8.2 0.8 0.4 69.0 6.6 3.4 13.7 3.0 1.2 0.5 0.9 0.7 1.8 16.5 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.7 0.0 0.1 0.1 0.0 0.1 17.1 41.6 11.4 21.9 40.6 17.8 16.5 18.1 15.6 14.9 19.2 26.0 56.4 48.1 6.8 791.0 1.1 5.2 3.3 7.5 8.6 27.4 3.7 6.3 13.1 2.8 16.7 3.7 22.9 0.3 0.1 2.3 0.0 2.1 3.8 1.3 5.5 47.1 10.9 5.3 422.8 0.4 0.2 21.4 0.5 2.2 2.5 5.0 43.9 17.0 14.6 94.2 177.1 0.7 14.2 16.7 21.0 1.5 5.6 27.4 8.8 1568.3 6.1 5.4 0.0 434.3 815.3 1.2 8.0 8.2 0.2 8.2 0.0 1.8 12.2 11.4 13.1 4.2 5.8 0.6 1.9 2.3 2.7 0.0 0.6 26.2 1.5 1.8 DOCK6 "KIAA1395, ZIR1" ENSG00000130158 "Dedicator of cytokinesis 6" Q96HP0 19 11199295-11262524 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 70.3;Cardiomyocytes: 185.4;Endothelial cells: 64.8;Hepatic stellate cells: 55.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 68.2;TIME: 68.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049423, HPA049424" Approved Supported Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" Cytosol "HPA049423: AB_2680760, HPA049424: AB_2680761" "unprognostic (2.69e-2)" "unprognostic (2.27e-1)" "unprognostic (9.51e-2)" "unprognostic (3.35e-2)" "unprognostic (4.72e-3)" "prognostic favorable (9.09e-4)" "unprognostic (2.54e-2)" "unprognostic (4.91e-1)" "unprognostic (1.23e-1)" "unprognostic (1.65e-2)" "unprognostic (2.57e-1)" "unprognostic (7.89e-2)" "unprognostic (1.25e-3)" "unprognostic (2.76e-1)" "unprognostic (1.51e-1)" "unprognostic (5.41e-2)" "unprognostic (2.95e-1)" 31.2 9.9 7.4 5.4 6.3 0.4 27.5 4.5 9.7 15.4 3.6 16.8 14.2 14.7 4.6 16.8 11.6 12.0 29.6 4.6 5.1 26.3 13.2 46.3 4.9 7.8 7.1 12.0 14.4 5.4 11.9 15.0 6.9 14.8 6.2 1.8 11.4 7.5 15.1 25.2 15.4 7.1 5.7 14.5 15.8 5.8 11.4 2.1 29.0 9.3 2.6 14.2 16.6 5.6 14.6 8.9 9.9 8.1 7.3 10.5 15.9 4.2 6.9 4.1 6.3 16.9 11.2 0.9 25.4 7.1 3.9 8.3 4.3 22.3 2.5 12.4 7.0 2.8 2.2 12.8 11.8 4.3 13.7 8.1 13.0 7.5 17.0 7.9 68.2 0.3 15.7 0.0 9.1 32.7 0.1 14.7 12.5 13.2 16.6 0.9 6.7 14.0 6.8 20.0 0.6 17.6 4.2 4.2 7.6 6.5 4.9 7.6 68.8 7.5 7.8 17.1 7.6 1.2 0.2 14.1 6.3 3.2 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 6.3 4.5 9.7 4.6 5.1 7.8 7.1 6.9 5.7 11.4 5.6 70.3 3.2 12.6 6.8 0.9 6.5 6.2 8.5 4.6 1.4 4.3 3.8 185.4 5.7 11.3 25.8 0.0 0.3 0.9 15.6 1.9 5.4 3.5 3.9 8.9 64.8 12.1 0.0 2.9 6.8 1.3 19.6 35.2 7.2 5.1 4.7 55.3 5.6 4.6 0.0 5.9 15.9 8.2 2.5 4.4 1.3 22.4 1.6 3.6 35.6 0.0 4.6 0.0 7.1 3.5 11.9 10.9 9.4 1.9 8.4 11.9 1.9 9.2 2.6 19.7 8.4 30.8 1.5 4.3 7.4 11.5 0.5 1.2 7.8 9.7 9.0 DUSP4 "HVH2, MKP-2, TYP" ENSG00000120875 "Dual specificity phosphatase 4" Q13115 8 29333064-29350684 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 32.2;stomach 1: 32.4" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 155.5;Ionocytes: 126.1;Pancreatic endocrine cells: 195.2" "Cancer enhanced" "Detected in all" "melanoma: 42.9" "Region enhanced" "Detected in many" "hippocampal formation: 20.9" "Immune cell enriched" "Detected in single" 9 "T-reg: 6.7" "Lineage enriched" "Detected in single" 20 "T-cells: 6.7" "Cell line enhanced" "Detected in many" "A549: 100.0;OE19: 91.7;SK-MEL-30: 157.2;WM-115: 122.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061967 Supported Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" Nucleoplasm "HPA061967: AB_2684648" "unprognostic (1.92e-1)" "unprognostic (5.97e-3)" "unprognostic (3.24e-1)" "unprognostic (6.54e-2)" "unprognostic (2.18e-2)" "unprognostic (7.66e-3)" "unprognostic (7.30e-2)" "unprognostic (7.08e-2)" "unprognostic (1.83e-2)" "unprognostic (9.73e-3)" "unprognostic (9.60e-3)" "unprognostic (3.15e-2)" "prognostic unfavorable (4.19e-4)" "unprognostic (6.88e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-2)" "unprognostic (6.07e-2)" 15.2 5.2 2.3 5.4 1.4 6.2 23.7 5.0 9.0 6.0 0.4 1.2 1.2 4.5 0.1 2.5 1.9 11.3 2.3 20.9 1.2 2.8 0.7 5.7 2.6 1.6 1.1 0.4 32.2 0.6 5.3 7.5 1.1 5.2 1.4 5.9 16.1 10.1 4.2 5.6 2.0 1.2 0.3 1.0 32.4 2.8 2.9 4.2 1.2 0.9 2.7 13.8 2.8 1.1 38.0 100.0 57.9 2.8 7.2 0.0 4.9 7.7 42.0 22.8 10.1 1.1 18.8 0.0 20.5 3.6 16.0 12.0 0.7 25.7 13.5 1.0 1.9 0.3 3.7 0.7 0.2 0.5 47.3 4.6 16.7 7.1 42.1 49.7 18.9 0.4 0.3 4.5 46.0 42.9 0.1 7.1 10.1 91.7 60.5 1.2 1.9 8.1 52.3 19.7 0.4 32.0 10.8 49.5 157.2 1.1 10.7 1.1 53.3 16.7 0.3 0.0 5.7 11.6 1.4 0.1 50.2 8.9 122.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 6.7 0.0 2.3 1.4 5.0 9.0 20.9 1.2 1.6 1.1 1.1 0.3 2.9 1.1 11.1 0.0 2.8 0.0 33.5 12.1 98.3 27.3 4.0 43.2 80.4 62.2 2.6 51.5 51.1 0.0 12.5 3.2 24.0 1.9 0.0 74.3 7.6 64.7 13.3 16.3 97.8 0.0 3.8 78.6 40.9 9.6 121.8 155.5 6.3 0.0 21.8 0.3 25.0 43.7 8.2 8.5 126.1 4.0 102.8 25.6 0.3 47.4 65.8 0.0 75.6 0.8 0.0 1.5 0.3 195.2 0.0 0.0 31.0 30.9 0.4 0.2 43.6 3.4 13.1 18.9 17.8 1.4 8.2 2.3 11.9 17.8 115.6 0.1 4.6 102.7 DUSP6 "MKP-3, PYST1" ENSG00000139318 "Dual specificity phosphatase 6" Q16828 12 89347235-89352501 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 226.2" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 246.8;granulocytes: 456.9;Kupffer cells: 266.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 97.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1636.7" "Group enriched" "Detected in all" 13 "granulocytes: 1636.7;monocytes: 842.3" "Cell line enhanced" "Detected in many" "AN3-CA: 427.6;NB-4: 325.8;SK-MEL-30: 253.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017566, HPA053188, HPA064692" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 17: WM-115 - Nervous system development" "Cluster 60: Granulocytes - Receptor signaling" "Nucleoplasm, Cytosol" "CAB017566: AB_647991, HPA053188: , HPA064692: " "unprognostic (7.35e-2)" "unprognostic (1.50e-2)" "unprognostic (5.77e-2)" "prognostic favorable (7.21e-4)" "unprognostic (2.35e-3)" "unprognostic (2.10e-3)" "unprognostic (3.76e-2)" "unprognostic (1.42e-1)" "unprognostic (8.63e-2)" "unprognostic (1.67e-2)" "unprognostic (3.15e-3)" "unprognostic (2.09e-1)" "unprognostic (5.91e-3)" "unprognostic (1.28e-2)" "unprognostic (3.95e-2)" "unprognostic (1.86e-2)" "unprognostic (2.84e-1)" 113.9 24.7 12.0 63.7 12.9 178.7 50.8 10.0 28.5 39.4 29.8 47.3 24.8 26.2 14.2 34.8 36.6 75.5 30.9 19.8 11.6 58.9 143.3 88.2 42.3 12.6 12.1 14.2 17.9 34.6 17.8 74.1 12.4 18.8 56.1 6.8 226.2 22.9 8.5 17.4 52.1 43.2 12.7 71.0 28.7 6.9 16.0 47.7 77.4 40.2 27.2 76.4 13.8 13.6 6.4 6.2 127.0 427.6 108.1 89.9 0.2 47.5 58.3 9.5 6.8 38.7 6.8 0.0 11.2 20.5 17.9 51.4 0.5 118.4 13.0 0.5 0.8 20.0 1.4 61.4 75.7 86.3 210.9 18.4 40.4 81.5 75.5 94.9 214.4 2.6 0.0 20.4 29.3 3.1 2.9 325.8 78.7 149.5 102.7 216.6 15.5 8.3 129.3 129.7 2.4 88.7 1.1 0.6 253.0 43.3 6.4 46.8 59.0 30.6 0.8 5.8 22.8 3.7 18.5 0.5 126.5 60.0 200.3 1636.7 558.9 247.2 9.8 842.3 4.5 2.7 2.7 3.5 97.0 11.6 1.6 3.2 230.5 14.8 841.0 12.2 6.7 455.2 12.0 12.9 10.0 28.5 19.8 11.6 12.6 12.1 12.4 12.7 16.0 13.6 182.9 102.5 246.8 12.4 18.0 90.9 79.4 97.4 38.7 2.1 30.3 85.5 11.1 81.5 80.5 180.3 33.3 72.6 36.1 58.3 17.6 12.6 1.6 67.4 14.1 159.8 19.2 6.6 19.6 14.0 4.2 54.5 19.4 134.2 456.9 24.2 177.8 130.2 49.6 1.7 3.8 13.2 46.8 266.7 61.2 1.7 1.5 193.2 12.4 33.7 198.9 8.7 20.6 24.6 2.4 17.1 45.7 3.4 16.2 26.1 17.0 27.5 21.2 2.4 26.3 21.4 29.7 2.6 7.0 14.7 24.7 49.3 42.3 3.5 22.0 61.4 DYSF "FER1L1, LGMD2B" ENSG00000135636 Dysferlin O75923 2 71453722-71686768 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 95.3" "Cell type enhanced" "Detected in many" "Adipocytes: 30.5;Endothelial cells: 43.7;Excitatory neurons: 34.7;Hepatic stellate cells: 32.2;Kupffer cells: 27.1;Oligodendrocytes: 62.7;Syncytiotrophoblasts: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 7 "neutrophil: 27.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 27.0" "Group enriched" "Detected in many" 5 "hTERT-RPE1: 31.9;HUVEC TERT2: 85.5;LHCN-M2: 75.3;RH-30: 78.5;TIME: 58.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002510, HPA017071, HPA021945" Enhanced Supported "Plasma membrane,Centriolar satellite" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Centriolar satellite" "CAB002510: AB_442097, HPA017071: AB_1847927, HPA021945: AB_1847928" "unprognostic (1.04e-1)" "unprognostic (7.66e-3)" "unprognostic (5.43e-3)" "unprognostic (1.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" "unprognostic (4.43e-2)" "unprognostic (1.14e-1)" "unprognostic (2.70e-1)" "unprognostic (3.21e-1)" "unprognostic (2.93e-1)" "unprognostic (6.43e-2)" "unprognostic (4.88e-3)" "unprognostic (1.22e-2)" "unprognostic (3.18e-2)" "unprognostic (1.36e-1)" "unprognostic (5.97e-3)" 10.1 1.7 1.0 11.5 1.1 31.6 4.3 4.1 7.7 1.9 0.7 7.0 2.0 2.3 0.5 7.4 3.2 4.6 16.8 0.2 3.8 3.6 6.5 8.3 3.7 14.8 5.1 1.3 1.5 2.3 1.5 21.1 13.7 3.3 2.5 0.5 1.3 4.8 95.3 1.2 3.1 10.2 2.0 21.4 2.5 1.1 10.2 2.3 4.6 32.3 0.9 6.9 1.8 1.8 1.1 0.0 3.3 3.0 0.0 0.0 6.1 0.1 0.8 2.2 1.5 0.4 1.0 0.0 12.1 0.1 3.4 2.5 0.0 1.2 1.1 0.0 0.0 0.2 0.2 0.0 0.3 0.1 0.0 1.5 0.0 2.3 10.6 31.9 85.5 0.2 8.4 0.0 75.3 0.0 0.0 5.8 8.1 0.0 0.9 0.0 78.5 0.0 2.6 0.2 0.0 0.0 4.1 0.7 0.1 7.9 0.3 0.8 58.1 0.3 3.8 0.2 1.1 0.0 0.0 0.0 0.0 13.3 0.0 0.0 4.1 0.1 0.5 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 27.0 0.4 0.1 0.0 0.0 1.4 1.0 1.1 4.1 7.7 0.2 3.8 14.8 5.1 13.7 2.0 10.2 1.8 30.5 3.2 8.1 1.0 1.0 2.4 0.0 0.1 0.0 1.1 0.3 0.6 24.0 0.0 1.3 0.0 0.0 8.1 0.7 0.1 0.0 0.4 4.8 0.7 1.3 43.7 0.0 2.7 34.7 0.2 3.8 2.2 0.0 9.3 2.5 0.3 32.2 13.4 11.4 0.0 13.0 0.2 0.0 27.1 3.0 6.0 0.6 10.2 0.0 16.9 5.8 0.1 0.0 2.5 62.7 0.1 0.0 0.7 0.1 0.2 0.0 2.1 0.7 0.2 6.6 5.2 5.5 0.6 1.1 0.1 1.6 66.2 1.1 0.9 0.0 0.1 ECE1 ECE ENSG00000117298 "Endothelin converting enzyme 1" P42892 1 21217247-21345572 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Hirschsprung disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 164.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 29.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 673.8;TIME: 588.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001490, HPA013616" Enhanced NA NA 1300000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA001490: AB_1078718, HPA013616: AB_1847963" "unprognostic (7.90e-2)" "unprognostic (1.01e-1)" "unprognostic (1.48e-1)" "unprognostic (1.99e-2)" "unprognostic (1.49e-2)" "unprognostic (1.46e-1)" "unprognostic (5.24e-2)" "unprognostic (1.23e-1)" "unprognostic (6.20e-2)" "unprognostic (1.92e-3)" "unprognostic (1.04e-1)" "unprognostic (2.56e-1)" "unprognostic (7.70e-2)" "unprognostic (3.55e-2)" "unprognostic (9.10e-2)" "unprognostic (1.97e-2)" "unprognostic (1.97e-2)" 87.3 123.2 26.5 47.7 29.4 48.1 79.4 23.0 30.1 61.4 12.6 71.0 30.1 42.4 10.0 26.7 46.9 36.8 70.9 21.3 33.7 38.1 54.0 72.1 35.7 34.4 25.7 71.0 91.8 125.0 47.4 66.5 30.4 53.1 34.7 14.7 33.6 25.1 19.8 34.3 46.1 42.3 21.2 48.5 43.3 22.7 28.1 21.1 51.4 33.2 34.9 58.8 43.8 27.5 93.0 60.1 77.9 38.3 111.0 116.4 44.1 135.4 236.8 72.9 66.6 44.1 275.8 34.0 323.6 138.8 157.7 38.4 32.6 64.9 63.5 83.0 27.2 48.7 89.9 34.8 144.3 7.1 11.8 61.6 74.3 112.6 55.8 199.2 673.8 27.6 10.0 17.7 62.9 19.4 14.6 11.4 23.2 26.3 46.5 17.5 45.0 49.2 114.0 17.0 26.4 63.1 134.3 79.2 57.4 42.5 55.9 20.2 588.7 160.7 77.9 73.3 79.9 26.4 49.0 39.1 332.6 16.5 196.6 0.2 8.4 3.3 2.9 10.0 4.2 6.1 6.1 4.6 0.7 4.1 4.0 2.7 29.8 1.5 7.8 2.8 8.6 7.2 26.5 29.4 23.0 30.1 21.3 33.7 34.4 25.7 30.4 21.2 28.1 27.5 164.0 19.2 7.5 46.4 25.1 20.3 19.7 81.6 18.8 5.0 71.3 44.7 18.9 10.0 54.7 23.9 0.0 6.0 12.4 105.8 5.9 25.8 1.5 19.6 35.2 106.1 25.2 20.2 19.2 56.7 35.0 51.8 20.9 51.8 18.4 35.4 97.1 36.0 3.3 0.0 14.8 13.0 57.0 9.6 14.3 4.2 43.5 17.3 7.2 31.9 25.5 50.4 8.2 13.6 22.5 100.4 106.5 55.3 29.4 34.9 45.7 7.5 24.2 4.4 39.5 72.7 47.5 1.3 5.9 8.5 16.1 10.5 17.9 80.6 21.6 40.8 EDN1 ET1 ENSG00000078401 "Endothelin 1" P05305 6 12290361-12297194 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 44.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 749.7;Ductal cells: 316.3;Glandular and luminal cells: 289.7;Pancreatic endocrine cells: 268.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "non-classical monocyte: 4.9" "Lineage enriched" "Detected in single" 6 "monocytes: 4.9" "Cell line enhanced" "Detected in many" "EFO-21: 660.4;HUVEC TERT2: 446.8;T-47d: 137.5;TIME: 334.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA031976, CAB032500, CAB037291" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Secreted to blood" NA Yes 9740 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli, Golgi apparatus" Nucleoplasm "CAB032500: AB_2096241, CAB037291: AB_259277, HPA031976: AB_10602489" "unprognostic (1.51e-2)" "unprognostic (2.38e-1)" "unprognostic (3.95e-2)" "unprognostic (9.72e-2)" "unprognostic (3.40e-1)" "unprognostic (1.91e-1)" "unprognostic (6.24e-2)" "unprognostic (2.94e-3)" "unprognostic (1.42e-1)" "unprognostic (8.92e-2)" "unprognostic (4.19e-2)" "unprognostic (3.17e-1)" "unprognostic (8.02e-3)" "unprognostic (2.09e-1)" "unprognostic (1.71e-1)" "unprognostic (1.34e-1)" "unprognostic (3.47e-1)" 44.6 1.8 14.7 7.3 13.8 4.7 23.6 13.6 18.2 6.2 9.7 10.6 10.4 7.0 6.3 12.1 9.4 13.5 7.8 12.6 12.2 7.7 3.1 36.6 5.6 15.1 13.6 2.6 9.6 1.4 1.1 18.5 15.2 5.5 14.5 1.0 12.1 8.9 7.6 11.8 9.8 11.3 13.1 12.3 10.4 4.7 15.7 1.7 3.4 6.4 2.4 9.9 5.9 14.2 10.3 57.6 1.1 0.1 0.3 0.2 0.2 18.2 16.0 15.0 12.4 74.6 8.6 0.0 660.4 7.2 9.2 5.4 0.0 10.6 11.0 0.8 0.0 0.0 2.1 2.3 0.8 0.0 0.0 0.4 6.2 3.0 2.1 4.7 446.8 0.0 0.0 0.0 56.8 1.6 0.2 0.3 0.6 10.4 0.7 0.2 5.1 0.1 35.3 9.4 0.6 0.0 1.8 53.1 0.1 117.2 137.5 0.8 334.3 37.1 30.1 0.7 23.5 0.3 0.4 1.3 0.3 0.0 1.6 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 4.9 0.1 0.0 0.0 14.7 13.8 13.6 18.2 12.6 12.2 15.1 13.6 15.2 13.1 15.7 14.2 190.7 173.1 23.8 2.9 0.8 189.9 749.7 99.9 151.4 0.2 68.7 26.8 2.2 8.6 110.6 38.6 0.0 1.8 0.8 189.7 3.9 316.3 13.3 187.2 16.3 236.8 15.6 2.7 3.6 218.9 0.4 9.0 22.4 289.7 1.3 0.8 169.2 1.8 1.8 1.7 3.0 43.8 12.2 5.0 6.7 19.8 5.6 5.3 8.8 6.5 10.9 0.3 0.0 3.5 0.6 268.5 145.7 0.4 0.4 185.8 119.6 8.3 27.4 0.4 6.6 1.8 21.8 1.0 0.6 53.7 64.5 0.8 9.7 0.1 196.6 141.8 EFNB1 "CFNS, Elk-L, EPLG2, LERK2" ENSG00000090776 "Ephrin B1" P98172 X 68829021-68842160 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 117.3;Granulosa cells: 134.5;Hepatic stellate cells: 143.5;Suprabasal keratinocytes: 120.5;Theca cells: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 97.0;hTCEpi: 74.1;PC-3: 70.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031489, HPA067188" Uncertain Supported "Plasma membrane" NA NA 1300000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "CAB031489: AB_631414, HPA067188: AB_2685799" "unprognostic (2.00e-1)" "unprognostic (1.33e-2)" "unprognostic (1.77e-2)" "prognostic unfavorable (3.32e-5)" "unprognostic (1.04e-1)" "unprognostic (2.48e-2)" "unprognostic (8.05e-3)" "unprognostic (2.15e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (3.94e-2)" "prognostic unfavorable (4.29e-4)" "unprognostic (1.29e-1)" "unprognostic (2.17e-3)" "unprognostic (2.76e-2)" "unprognostic (8.03e-2)" "unprognostic (1.72e-3)" "unprognostic (1.86e-2)" 47.0 23.7 9.3 8.2 9.5 2.3 41.2 8.7 11.8 27.1 8.7 27.6 19.1 19.4 10.7 32.0 19.6 18.3 32.5 9.1 8.9 44.0 11.6 41.6 4.3 9.4 9.1 14.3 7.6 16.5 10.3 25.4 8.9 19.8 13.2 1.2 11.2 16.2 9.1 52.5 20.6 8.8 9.6 26.1 18.1 6.3 9.7 5.6 19.6 9.5 4.8 25.9 27.9 9.3 10.4 5.3 41.9 15.6 21.7 13.4 21.9 8.7 9.5 3.8 2.8 4.8 19.0 2.5 56.7 3.3 5.0 54.3 40.0 97.0 2.1 4.3 10.2 2.6 2.3 8.5 20.0 1.9 21.3 25.0 74.1 9.4 42.4 3.4 29.3 5.3 2.8 0.2 3.3 8.5 4.2 2.0 29.0 63.5 70.9 18.6 4.4 16.6 15.9 36.1 15.6 7.5 6.7 2.0 2.6 31.7 1.6 3.6 49.7 7.2 8.9 19.6 3.3 0.1 2.3 2.5 3.6 11.3 4.7 0.0 0.6 0.3 0.4 1.7 0.3 0.3 0.4 0.4 3.5 0.2 0.3 0.2 0.1 0.7 1.1 0.5 0.2 0.5 9.3 9.5 8.7 11.8 9.1 8.9 9.4 9.1 8.9 9.6 9.7 9.3 81.1 3.2 1.1 2.6 3.2 117.3 66.2 60.7 93.4 3.3 3.6 11.2 8.2 20.0 12.8 22.0 0.0 11.4 5.9 59.4 0.0 16.4 0.4 2.6 7.6 42.4 8.4 2.7 1.0 15.6 75.9 20.5 21.4 4.5 4.5 134.5 143.5 4.8 12.4 1.7 1.0 27.6 8.2 9.1 23.8 1.3 27.4 8.6 21.4 2.8 5.9 12.5 2.1 0.5 0.6 46.3 52.6 8.2 2.3 40.2 28.6 5.7 2.8 1.3 13.1 8.7 12.5 2.0 3.8 76.2 120.5 11.2 4.7 116.2 29.8 93.6 EHD4 PAST4 ENSG00000103966 "EH domain containing 4" Q9H223 15 41895933-41972557 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 189.5;Urothelial cells: 200.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 103.8;TIME: 172.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049890, HPA049986, HPA052729, HPA066751" Approved Approved "Plasma membrane" NA NA 440000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "HPA049890: AB_2680936, HPA049986: AB_2680983, HPA052729: AB_2681928, HPA066751: AB_2685713" "unprognostic (1.45e-1)" "unprognostic (1.37e-1)" "unprognostic (4.34e-3)" "unprognostic (3.36e-2)" "unprognostic (3.46e-2)" "unprognostic (4.48e-3)" "unprognostic (1.52e-1)" "unprognostic (3.36e-3)" "unprognostic (2.25e-1)" "unprognostic (3.74e-1)" "unprognostic (6.93e-2)" "unprognostic (2.35e-1)" "unprognostic (5.05e-2)" "unprognostic (3.49e-2)" "unprognostic (3.19e-2)" "unprognostic (8.27e-2)" "unprognostic (2.72e-1)" 21.6 4.6 3.1 11.8 3.2 10.9 16.4 7.5 3.5 9.4 5.3 12.1 5.5 9.6 10.5 15.0 9.8 15.2 27.8 3.3 3.8 14.3 9.6 15.0 12.8 4.8 4.0 5.6 14.3 12.8 5.8 8.3 4.8 9.5 10.2 6.1 10.4 9.7 4.4 14.3 12.4 12.9 5.2 7.4 9.9 2.8 4.0 5.3 18.4 4.7 8.8 23.8 9.0 6.6 28.7 9.8 9.3 9.6 4.6 6.5 8.1 14.9 31.4 25.9 36.1 41.4 16.1 5.9 39.2 18.8 51.6 28.4 13.9 32.6 19.0 35.7 11.7 8.7 13.5 7.1 11.3 4.0 24.4 5.5 12.6 26.3 28.8 9.9 103.8 8.7 9.2 6.6 21.1 12.2 4.2 4.5 7.1 27.8 33.5 0.1 24.5 9.4 23.4 57.0 15.4 6.5 10.9 23.2 17.0 9.0 22.9 5.6 172.8 8.1 15.7 30.5 73.1 18.1 30.9 12.4 10.3 9.4 71.6 1.1 14.0 9.0 4.0 12.4 6.1 2.1 6.2 5.0 14.9 2.6 2.6 3.8 2.3 4.4 5.2 2.5 7.9 8.0 3.1 3.2 7.5 3.5 3.3 3.8 4.8 4.0 4.8 5.2 4.0 6.6 94.9 6.4 44.2 3.9 20.0 81.6 189.5 68.1 34.1 4.9 31.4 20.1 36.6 30.0 69.0 44.1 31.3 10.1 22.2 96.0 7.9 71.3 16.1 66.1 9.7 114.9 22.6 5.7 1.2 62.6 20.4 21.3 25.5 72.4 61.6 16.2 54.7 8.7 89.0 1.7 0.7 22.5 28.5 35.6 52.7 34.7 7.5 46.3 19.6 12.2 53.5 37.5 4.1 26.7 2.7 75.1 70.9 4.9 31.5 49.9 71.4 4.6 60.8 27.8 13.1 8.0 29.0 5.4 8.2 29.3 79.8 17.4 27.8 21.2 37.3 200.1 ELK3 "ERP, NET, SAP2" ENSG00000111145 "ETS transcription factor ELK3" P41970 12 96194375-96269824 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 170.7;Endothelial cells: 148.0;Hepatic stellate cells: 160.6;Respiratory ciliated cells: 103.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001600 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 13: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Mitochondria "HPA001600: AB_1078752" "unprognostic (3.11e-1)" "unprognostic (8.81e-3)" "unprognostic (6.38e-2)" "unprognostic (5.77e-2)" "unprognostic (7.18e-3)" "unprognostic (1.12e-1)" "unprognostic (1.15e-1)" "unprognostic (5.10e-3)" "unprognostic (7.39e-2)" "prognostic unfavorable (4.93e-4)" "unprognostic (2.29e-2)" "unprognostic (1.13e-1)" "unprognostic (1.20e-3)" "unprognostic (2.90e-3)" "unprognostic (1.61e-1)" "unprognostic (1.70e-1)" "unprognostic (2.05e-2)" 37.1 14.4 5.4 34.2 6.1 18.4 28.4 14.4 5.8 28.0 11.7 15.6 9.2 35.2 9.3 38.1 16.9 30.2 23.9 4.7 7.2 14.0 10.8 27.5 38.0 9.1 7.9 10.2 9.0 11.6 5.8 27.0 7.9 13.1 13.9 2.9 15.3 15.3 11.2 12.5 13.5 37.9 7.0 41.8 14.8 8.6 8.3 19.7 21.8 22.2 37.5 29.2 24.5 6.6 50.3 29.5 29.7 15.8 73.7 137.3 7.6 62.3 118.5 48.6 37.3 1.7 36.6 8.0 20.9 70.4 36.4 17.6 3.3 99.8 85.0 21.7 11.4 2.5 12.2 11.2 22.3 24.2 5.7 81.3 18.4 100.4 75.4 98.5 117.8 6.0 6.0 32.3 166.4 7.6 4.8 16.4 36.3 7.1 38.8 39.7 49.8 9.1 41.7 13.0 1.4 31.4 20.5 9.1 32.0 44.7 5.0 13.3 73.2 132.4 52.2 82.5 54.8 61.7 55.0 1.8 47.0 28.2 94.1 7.1 23.5 0.5 11.1 13.0 42.5 23.2 25.7 15.0 17.7 19.0 15.4 11.4 7.4 20.1 12.1 7.1 45.4 12.8 5.4 6.1 14.4 5.8 4.7 7.2 9.1 7.9 7.9 7.0 8.3 6.6 170.7 6.4 22.3 3.9 22.3 32.6 44.6 15.0 10.8 0.7 7.1 8.1 6.6 2.8 39.4 5.5 4.2 1.2 27.5 2.1 5.9 21.8 1.0 49.0 19.7 148.0 1.2 12.4 4.2 15.6 3.9 35.2 3.1 44.0 17.1 1.3 160.6 4.3 24.5 0.0 1.9 3.4 2.0 32.0 39.7 2.5 11.5 31.4 12.4 39.4 23.6 5.8 9.2 5.5 5.3 56.8 3.4 10.5 29.5 45.7 0.5 0.7 103.1 0.6 13.1 27.7 19.9 0.2 12.6 24.4 27.0 1.1 32.6 10.6 3.0 79.0 EMP1 "CL-20, TMP" ENSG00000134531 "Epithelial membrane protein 1" P54849 12 13196723-13219941 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2255.1;vagina: 819.5" "Cell type enhanced" "Detected in many" "Adipocytes: 835.5;Basal keratinocytes: 694.1;Endothelial cells: 662.2;Squamous epithelial cells: 888.5;Suprabasal keratinocytes: 687.6;Urothelial cells: 1193.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "myeloid DC: 3.4" "Lineage enriched" "Detected in single" 13 "dendritic cells: 3.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 1166.6;fHDF/TERT166: 861.7;HaCaT: 766.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 4.5;spinal cord: 16.0" HPA046912 Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA046912: " "unprognostic (1.40e-2)" "unprognostic (7.30e-2)" "unprognostic (8.01e-2)" "unprognostic (1.07e-2)" "unprognostic (1.69e-1)" "unprognostic (1.39e-1)" "unprognostic (8.41e-3)" "unprognostic (1.94e-1)" "unprognostic (2.67e-2)" "prognostic unfavorable (2.26e-8)" "prognostic unfavorable (7.46e-4)" "unprognostic (2.98e-1)" "unprognostic (4.84e-2)" "unprognostic (3.05e-2)" "unprognostic (3.45e-2)" "unprognostic (3.25e-1)" "prognostic unfavorable (9.69e-8)" 536.6 42.0 18.6 63.9 20.2 20.7 166.7 18.2 28.4 463.2 14.2 100.7 39.5 61.6 12.5 2255.1 84.8 205.8 121.8 17.7 46.5 93.9 35.1 177.9 11.4 29.5 22.9 21.8 86.8 20.6 29.9 76.9 27.2 39.6 56.4 5.5 377.8 20.3 27.0 150.9 41.8 149.2 25.1 26.2 48.5 9.2 20.8 28.4 133.5 35.6 165.4 205.7 819.5 22.1 373.5 19.4 9.1 1.9 563.2 1166.6 1.5 269.6 489.4 135.7 172.3 2.7 612.6 2.2 187.3 861.7 60.0 766.6 10.8 35.7 182.9 7.2 0.8 1.2 61.9 0.2 135.6 2.6 2.1 369.8 50.9 432.7 126.4 107.3 316.8 0.2 2.0 6.2 325.4 1.6 0.8 8.3 6.6 69.8 62.3 1.0 37.1 3.4 396.4 4.4 0.3 0.3 120.1 17.4 211.9 69.9 3.1 2.2 349.8 302.2 106.7 287.0 146.8 1.5 4.1 2.5 441.2 2.2 363.8 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 18.6 20.2 18.2 28.4 17.7 46.5 29.5 22.9 27.2 25.1 20.8 22.1 835.5 205.1 88.5 8.1 3.7 694.1 362.3 34.8 223.7 0.1 316.5 91.7 12.9 27.1 166.8 18.4 0.0 1.2 7.6 481.5 15.6 28.7 0.8 76.0 167.6 662.2 47.6 0.0 0.9 4.4 1.8 470.5 62.2 160.3 50.4 0.1 157.1 2.2 39.8 0.0 0.4 13.5 6.1 37.1 481.2 2.1 69.6 105.8 473.2 7.5 7.0 2.4 0.0 0.5 0.2 62.2 343.0 109.4 12.7 413.0 48.6 0.5 60.2 0.4 6.6 202.1 170.1 1.1 0.9 888.5 687.6 1.1 23.0 5.1 26.6 1193.8 ENTPD4 "KIAA0392, LALP70, LAP70, LYSAL1, NTPDase-4, UDPase" ENSG00000197217 "Ectonucleoside triphosphate diphosphohydrolase 4" Q9Y227 8 23385783-23457695 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017655 Supported Approved Vesicles NA NA 82000 "Cluster 2: Granulocytes - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" Vesicles "HPA017655: AB_1848181" "unprognostic (2.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (5.06e-2)" "unprognostic (7.86e-3)" "unprognostic (2.00e-2)" "unprognostic (2.99e-3)" "unprognostic (2.07e-2)" "unprognostic (8.74e-2)" "unprognostic (2.82e-1)" "unprognostic (1.20e-1)" "unprognostic (4.55e-2)" "unprognostic (1.39e-1)" "unprognostic (1.11e-1)" "unprognostic (6.62e-2)" "unprognostic (3.72e-2)" 16.3 11.5 8.6 24.2 10.5 30.5 14.8 11.1 16.2 17.0 8.1 19.8 18.1 16.8 17.3 12.6 13.7 14.6 21.2 10.8 12.3 12.2 13.7 20.0 29.3 13.1 9.2 13.5 21.4 27.2 18.3 17.2 12.8 16.8 20.3 32.7 22.0 13.4 15.2 12.4 26.2 16.5 7.6 25.4 20.3 19.9 12.5 14.5 14.7 15.9 29.8 16.7 16.6 11.6 20.8 28.7 34.0 23.5 29.0 36.8 35.0 33.1 30.4 21.3 33.2 40.3 26.4 35.5 22.9 32.8 32.9 24.5 15.8 29.0 40.3 8.6 11.5 18.4 18.1 14.2 23.7 9.8 34.8 22.8 34.7 28.4 29.9 51.9 31.2 26.7 13.2 30.6 36.4 9.3 14.8 11.9 20.1 26.2 10.2 14.3 34.6 10.8 27.0 24.1 27.2 26.6 12.0 17.0 23.7 67.0 12.9 13.6 38.6 39.1 38.3 43.7 24.1 24.7 11.5 45.5 51.3 11.5 39.4 17.0 5.7 13.4 7.4 8.6 8.8 8.7 7.3 8.1 7.5 6.5 9.2 7.3 14.4 4.8 7.0 6.8 6.3 6.9 8.6 10.5 11.1 16.2 10.8 12.3 13.1 9.2 12.8 7.6 12.5 11.6 15.9 19.2 34.5 10.7 25.8 6.5 12.0 17.6 8.6 32.1 11.4 8.6 24.6 7.2 27.3 14.7 14.6 16.1 33.4 25.1 0.0 15.6 8.6 13.6 21.6 15.8 17.3 10.3 31.4 16.9 16.9 16.9 23.9 23.9 17.7 18.9 12.1 11.5 12.3 47.1 37.4 19.7 20.3 14.2 15.5 19.2 7.2 18.2 12.4 19.7 19.4 15.2 18.6 23.1 23.1 21.8 13.3 8.6 46.9 18.9 18.8 5.0 15.0 35.9 13.1 14.3 14.6 21.5 22.8 9.5 5.5 20.2 21.3 11.7 12.4 18.9 ETS1 "ETS-1, EWSR2, FLJ10768" ENSG00000134954 "ETS proto-oncogene 1, transcription factor" P14921 11 128458761-128587558 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Immunity, Transcription, Transcription regulation" DNA-binding Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 328.8" "Cell type enhanced" "Detected in many" "Adipocytes: 263.1;dendritic cells: 378.9;Endothelial cells: 190.4;Hepatic stellate cells: 213.8;NK-cells: 399.6;T-cells: 323.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 352.9;JURKAT: 362.3;U-698: 462.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002575, HPA063230" Enhanced Enhanced Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB002575: AB_563721, HPA063230: AB_2684965" "unprognostic (1.76e-2)" "unprognostic (2.49e-1)" "unprognostic (3.18e-3)" "unprognostic (6.22e-2)" "unprognostic (3.07e-1)" "unprognostic (2.56e-1)" "unprognostic (1.24e-2)" "unprognostic (1.57e-1)" "unprognostic (1.35e-2)" "unprognostic (7.17e-2)" "unprognostic (2.46e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.30e-5)" "unprognostic (2.02e-1)" "unprognostic (3.08e-2)" "unprognostic (1.38e-1)" "unprognostic (5.48e-3)" 101.2 19.2 11.7 145.7 10.4 35.3 65.4 9.8 14.1 35.9 8.9 31.2 26.9 36.5 9.3 21.8 20.2 62.5 43.0 8.9 11.3 30.4 47.6 76.2 277.1 13.1 14.7 27.0 20.1 28.4 7.8 56.3 13.4 17.1 31.4 1.8 16.5 20.7 25.6 18.1 49.3 38.1 11.6 185.8 46.1 8.0 15.2 328.8 39.8 42.3 250.2 67.9 19.2 11.3 87.7 15.7 72.8 0.3 30.7 49.3 0.2 65.7 140.2 80.9 77.3 5.1 91.7 312.1 65.7 109.5 184.7 29.8 7.0 190.0 169.0 66.6 1.1 352.9 6.4 0.3 82.2 36.7 4.0 97.2 15.0 69.6 252.2 46.1 67.9 362.3 0.6 63.3 98.1 0.0 185.7 27.4 27.0 7.9 55.0 50.4 118.7 24.5 64.2 95.6 0.9 5.0 34.5 0.7 73.6 48.5 0.3 17.7 126.1 180.5 57.1 35.5 109.1 46.7 8.9 462.5 32.2 68.0 162.1 51.2 0.1 6.6 20.4 0.3 28.9 12.3 27.0 25.0 0.2 9.2 32.5 26.1 1.1 27.8 1.0 6.2 33.3 9.5 11.7 10.4 9.8 14.1 8.9 11.3 13.1 14.7 13.4 11.6 15.2 11.3 263.1 25.6 26.5 2.9 125.6 114.8 41.0 12.4 1.8 0.0 8.2 7.2 9.0 4.3 24.3 11.0 0.0 0.2 378.9 13.1 0.0 31.9 6.2 26.3 51.0 190.4 15.5 13.7 2.0 22.6 0.5 45.5 17.3 66.2 19.6 1.3 213.8 5.4 7.3 0.0 25.6 15.0 10.2 18.3 48.2 1.5 14.0 12.5 69.4 65.6 16.8 0.2 399.6 55.3 9.5 99.3 6.6 15.4 129.6 26.8 2.2 4.6 5.9 0.2 105.2 55.5 76.6 0.7 1.8 1.5 63.2 0.4 323.2 40.4 5.8 32.6 ETS2 ENSG00000157557 "ETS proto-oncogene 2, transcription factor" P15036 21 38805183-38824955 "Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 701.0;Basal squamous epithelial cells: 863.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 33.6;granulocytes: 37.0;monocytes: 32.4" "Cell line enhanced" "Detected in many" "HEL: 309.0;hTCEpi: 269.6;hTERT-HME1: 210.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003176 Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 36: HEL - Hemostasis" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Plasma membrane, Cytosol" "HPA003176: AB_2666824" "unprognostic (2.06e-1)" "unprognostic (5.91e-2)" "unprognostic (9.16e-3)" "unprognostic (5.33e-3)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (1.88e-3)" "unprognostic (7.36e-2)" "unprognostic (8.99e-3)" "unprognostic (3.66e-2)" "unprognostic (1.02e-1)" "unprognostic (1.77e-1)" "unprognostic (1.95e-2)" "unprognostic (2.12e-1)" "unprognostic (1.89e-1)" "unprognostic (8.10e-2)" "unprognostic (7.10e-2)" 109.9 29.7 51.4 95.5 43.3 167.1 87.7 31.6 72.5 89.6 61.4 119.3 131.3 77.5 27.9 90.6 72.5 132.1 68.0 50.9 43.2 66.1 230.7 185.5 38.0 50.0 39.9 65.7 37.5 61.9 56.6 73.6 45.0 80.1 146.5 7.5 50.3 45.7 149.7 248.3 179.7 78.0 47.9 201.0 72.7 7.6 54.0 43.7 62.5 42.8 34.8 210.2 103.6 44.4 120.1 26.2 16.6 5.6 18.8 61.3 49.2 27.4 154.1 36.2 46.5 23.0 35.1 24.7 13.3 25.0 48.5 35.7 28.0 71.2 63.8 24.5 12.0 309.0 152.6 62.2 196.9 18.4 28.2 39.8 269.6 49.6 210.2 22.0 28.3 17.2 31.3 0.2 14.4 20.1 54.1 22.2 56.0 39.3 18.2 189.6 10.2 25.2 50.2 74.4 14.2 18.4 78.4 32.8 6.2 5.7 1.9 36.3 30.8 83.0 13.0 55.3 60.5 0.5 0.3 25.2 20.7 69.4 70.8 21.0 19.5 7.0 3.2 24.9 3.9 0.4 3.0 4.7 33.6 0.4 3.2 3.2 37.0 0.3 32.4 8.1 0.3 8.9 51.4 43.3 31.6 72.5 50.9 43.2 50.0 39.9 45.0 47.9 54.0 44.4 253.0 51.3 156.6 6.2 10.8 427.4 701.0 150.8 863.4 2.1 84.2 69.7 25.6 51.5 141.9 51.5 0.0 58.4 17.5 150.7 11.7 73.7 4.0 241.1 127.4 312.7 91.8 36.4 39.6 108.5 109.3 98.7 161.1 497.9 51.3 0.9 242.0 262.4 62.1 0.0 10.7 266.0 79.3 150.8 291.7 2.0 18.0 253.4 67.6 74.0 41.0 1.5 3.1 4.0 3.1 127.6 175.1 24.8 21.0 184.0 162.2 47.2 107.9 1.6 52.6 81.8 108.8 0.6 3.3 522.6 486.4 177.6 28.8 8.2 243.3 338.7 EXOC3L2 "FLJ36147, XTP7" ENSG00000283632 "Exocyst complex component 3 like 2" 19 45212370-45245407 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "kidney: 19.0;thyroid gland: 17.9" "Group enriched" "Detected in some" 4 "Adipocytes: 15.3;Endothelial cells: 17.7;Hepatic stellate cells: 51.4;Theca cells: 21.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HEL: 19.1;K-562: 16.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041595, HPA061110" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Nucleoplasm, Golgi apparatus, Cytosol" "HPA041595: AB_10794521, HPA061110: AB_2684431" 4.3 8.3 0.3 2.1 0.6 1.6 2.9 0.5 0.4 4.0 1.6 2.7 2.4 4.9 0.4 1.9 2.8 2.3 2.3 0.4 0.3 19.0 2.7 2.7 1.1 0.7 0.5 0.9 2.7 3.3 5.0 0.4 0.5 5.2 0.7 0.1 1.8 2.2 0.9 2.1 3.2 1.9 0.3 8.3 2.9 3.3 0.4 0.4 17.9 0.3 0.5 3.2 2.4 0.7 0.1 0.3 2.5 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.3 0.1 2.2 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.1 19.1 0.6 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 16.6 0.2 0.0 0.2 0.0 0.0 0.1 0.1 0.5 1.1 0.0 0.1 0.0 0.2 0.3 0.0 0.1 0.1 0.1 1.0 0.1 0.3 0.6 0.8 1.5 0.2 0.1 0.2 0.1 0.0 0.1 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.5 0.4 0.4 0.3 0.7 0.5 0.5 0.3 0.4 0.7 15.3 0.0 1.3 0.7 0.7 0.4 0.3 0.0 0.0 0.7 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 17.7 0.0 0.0 1.5 0.0 0.0 0.5 0.0 0.2 0.0 0.4 51.4 0.3 0.0 0.0 1.1 0.6 0.0 1.6 0.0 0.0 1.8 2.8 0.0 0.0 0.1 0.2 2.1 0.5 0.7 0.0 0.0 1.9 0.1 0.2 0.1 0.1 0.0 0.2 0.0 0.3 0.6 0.4 6.2 0.2 0.9 0.0 0.1 21.2 0.0 0.3 F8 "DXS1253E, F8C, FVIII, HEMA" ENSG00000185010 "Coagulation factor VIII" P00451 X 154835788-155026940 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Disease variant, FDA approved drug targets, Hemophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 53.2" "Group enriched" "Detected in many" 10 "Adipocytes: 118.6;Endothelial cells: 120.4;Hepatic stellate cells: 371.2" "Cancer enhanced" "Detected in all" "renal cancer: 7.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-2197: 16.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB018777 Enhanced "Secreted to blood" NA NA 25000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB018777: AB_640320" "unprognostic (2.09e-1)" "unprognostic (5.66e-4)" "unprognostic (4.94e-2)" "unprognostic (8.32e-5)" "unprognostic (1.26e-1)" "unprognostic (5.05e-2)" "unprognostic (6.05e-2)" "unprognostic (8.27e-2)" "unprognostic (6.58e-2)" "unprognostic (1.68e-1)" "unprognostic (1.67e-2)" "unprognostic (5.58e-2)" "unprognostic (1.24e-2)" "unprognostic (2.16e-3)" "unprognostic (1.69e-1)" "unprognostic (1.17e-2)" "unprognostic (4.44e-2)" 29.4 15.2 7.8 2.5 8.6 2.1 19.3 7.4 11.2 7.5 9.9 9.6 2.9 10.9 9.1 4.0 7.9 5.0 53.2 8.2 8.5 14.1 20.1 16.7 4.7 8.6 8.4 14.5 11.6 5.6 6.4 3.3 8.6 9.0 3.8 6.2 4.7 7.5 20.6 3.6 5.0 6.3 7.8 17.9 5.7 6.1 8.9 3.2 10.9 28.1 3.7 8.1 3.7 7.8 6.1 4.5 0.9 2.1 6.5 10.1 0.7 2.9 1.8 2.0 3.4 0.3 6.8 12.0 9.5 3.0 4.7 0.8 1.0 1.0 1.8 5.1 1.9 2.4 2.8 0.2 3.0 2.1 5.6 7.2 0.6 1.8 2.4 3.5 1.2 5.7 1.1 9.0 10.0 2.7 1.7 1.9 1.6 1.8 4.5 1.4 1.5 1.8 1.8 1.3 3.7 2.8 7.0 0.8 3.9 1.0 2.1 4.9 1.5 10.3 5.5 16.6 3.7 5.3 5.1 6.0 9.4 12.3 5.5 4.6 2.8 0.9 5.2 2.4 10.3 2.1 3.1 5.5 2.7 1.9 1.6 4.1 4.4 3.3 2.4 0.4 4.6 2.7 7.8 8.6 7.4 11.2 8.2 8.5 8.6 8.4 8.6 7.8 8.9 7.8 118.6 0.0 6.3 13.1 2.3 1.8 2.5 1.6 4.0 8.1 3.7 4.2 17.7 7.2 1.9 3.7 2.1 0.9 2.0 0.6 7.9 3.1 1.4 1.5 1.5 120.4 0.0 8.4 7.2 0.7 0.7 6.8 0.0 1.5 1.3 8.2 371.2 11.8 3.2 6.7 5.0 0.6 0.0 19.9 1.1 3.3 11.5 3.0 0.0 8.4 2.4 6.8 2.1 7.5 6.0 4.5 0.1 5.3 2.0 1.4 0.9 11.4 2.4 3.5 6.6 11.1 13.0 2.3 3.4 1.5 1.1 0.1 4.0 4.3 0.4 2.1 FAM110D "FLJ14050, GRRP1" ENSG00000197245 "Family with sequence similarity 110 member D" Q8TAY7 1 26159079-26163962 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 12 "Adipocytes: 82.7;Endothelial cells: 63.5;Hepatic stellate cells: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "TIME: 1.2;U-2 OS: 1.4;U-937: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA013664 Approved NA NA "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA013664: AB_1234332" "unprognostic (7.53e-2)" "unprognostic (4.45e-3)" "unprognostic (4.80e-4)" "unprognostic (1.84e-2)" "unprognostic (1.07e-3)" "unprognostic (3.16e-3)" "unprognostic (7.67e-5)" "unprognostic (2.21e-1)" "unprognostic (1.66e-1)" "unprognostic (4.51e-2)" "unprognostic (7.29e-3)" "unprognostic (6.63e-2)" "unprognostic (9.87e-2)" "unprognostic (6.94e-2)" "unprognostic (2.91e-1)" "unprognostic (1.51e-1)" "unprognostic (2.96e-1)" 10.9 1.3 4.1 0.6 3.0 0.8 8.5 3.1 3.7 4.8 2.0 2.9 1.1 7.9 0.8 1.9 7.4 2.3 6.2 3.1 3.2 4.0 0.4 4.2 1.1 4.7 3.6 1.3 2.2 1.1 1.3 0.6 4.1 3.1 0.5 0.3 2.4 0.7 4.2 3.0 3.1 2.8 4.5 0.8 3.3 0.6 4.1 0.9 4.7 2.1 0.4 4.0 3.6 3.3 0.1 0.1 0.5 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.6 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.3 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.2 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.5 0.5 0.1 0.0 0.1 0.4 0.1 0.2 1.2 0.1 1.4 0.1 0.0 0.0 0.2 0.1 0.0 1.0 0.0 1.3 0.2 0.2 0.2 0.1 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.2 1.0 0.4 0.1 0.2 0.0 0.0 4.1 3.0 3.1 3.7 3.1 3.2 4.7 3.6 4.1 4.5 4.1 3.3 82.7 0.0 3.4 0.3 0.9 1.0 0.9 0.0 2.2 2.3 1.3 1.8 3.1 2.8 1.3 0.0 0.0 0.1 0.6 0.0 0.0 0.1 0.4 0.2 0.5 63.5 0.0 2.7 0.4 0.0 0.0 2.5 0.0 0.2 0.0 0.3 34.6 0.0 0.0 1.7 0.7 0.0 0.0 1.3 1.8 0.5 0.6 0.4 0.0 4.7 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 1.4 0.0 1.4 1.8 0.2 0.7 0.8 0.9 0.3 0.3 0.5 0.0 0.3 FAM135A "FLJ20176, KIAA1411" ENSG00000082269 "Family with sequence similarity 135 member A" Q9P2D6 6 70412941-70561174 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 29.8" "Cell type enhanced" "Detected in all" "Excitatory neurons: 170.1;Horizontal cells: 238.9;Inhibitory neurons: 172.8;Microglial cells: 132.1;Oligodendrocyte precursor cells: 219.2;Oligodendrocytes: 121.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RH-30: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031743, HPA031744" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 37: Intestine - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm Cytosol "HPA031743: AB_10600767, HPA031744: AB_10601101" "unprognostic (5.79e-2)" "unprognostic (1.64e-1)" "prognostic favorable (8.00e-4)" "unprognostic (1.59e-1)" "unprognostic (1.66e-2)" "unprognostic (1.08e-1)" "unprognostic (6.69e-4)" "unprognostic (4.08e-2)" "unprognostic (3.87e-2)" "unprognostic (1.58e-1)" "unprognostic (1.02e-1)" "unprognostic (1.41e-1)" "prognostic favorable (3.46e-4)" "unprognostic (3.99e-1)" "unprognostic (2.75e-1)" "unprognostic (6.26e-2)" "unprognostic (2.65e-2)" 2.6 2.8 2.5 4.8 3.6 1.3 2.5 8.1 3.3 4.9 0.6 10.7 13.6 6.3 2.5 29.8 4.1 7.0 4.1 3.2 2.1 4.9 2.4 4.2 3.8 2.4 2.3 6.3 6.0 9.7 1.9 4.0 2.4 16.1 11.1 8.2 4.5 3.5 2.6 9.6 11.5 3.7 1.2 3.5 10.7 10.1 2.2 2.9 3.8 6.5 6.4 4.9 7.1 3.7 7.9 4.8 9.5 6.1 4.5 3.2 8.9 2.5 5.0 2.6 4.3 8.9 6.2 14.3 18.1 1.9 12.6 7.3 9.6 5.6 4.6 6.8 8.2 6.2 4.6 8.0 5.5 12.3 6.4 2.9 13.8 5.0 13.4 3.1 7.2 4.4 10.6 6.8 3.1 0.8 2.2 5.5 6.4 9.2 3.9 6.8 31.3 6.8 9.8 4.0 10.1 3.1 2.9 2.6 3.0 6.3 1.8 5.2 3.6 2.2 5.7 2.2 5.8 8.5 10.3 5.5 1.6 10.4 4.2 1.8 2.3 0.1 0.8 2.0 0.9 1.6 0.7 0.3 3.5 2.0 1.1 0.7 0.6 2.7 3.3 0.5 0.9 0.9 2.5 3.6 8.1 3.3 3.2 2.1 2.4 2.3 2.4 1.2 2.2 3.7 12.0 28.9 12.5 85.8 10.8 15.9 12.9 8.3 31.3 20.8 4.5 4.1 11.5 17.2 8.9 20.2 29.2 2.9 4.7 49.9 5.9 6.7 30.4 13.9 15.6 13.0 23.4 1.7 170.1 12.4 1.5 10.2 45.9 21.4 8.8 13.5 9.7 6.5 5.6 238.9 172.8 29.2 16.2 10.6 15.5 23.8 15.5 11.9 5.4 132.1 11.9 13.8 4.1 219.2 121.3 18.4 31.7 13.2 6.4 35.4 24.0 10.0 9.9 26.4 6.6 11.6 9.3 33.2 10.5 71.4 33.5 8.2 4.6 10.9 25.5 15.8 FAM241A "C4orf32, FLJ39370" ENSG00000174749 "Family with sequence similarity 241 member A" Q8N8J7 4 112145454-112195256 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 272.0;Alveolar cells type 1: 60.9;Alveolar cells type 2: 69.9;Breast glandular cells: 87.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Daudi: 41.3;HUVEC TERT2: 28.0" "Low region specificity" "Detected in all" "HPA062443, HPA069294" Approved Enhanced "Golgi apparatus" No No "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus" "HPA062443: AB_2684765, HPA069294: AB_2686111" "unprognostic (3.07e-1)" "unprognostic (1.11e-2)" "unprognostic (2.42e-2)" "unprognostic (5.58e-2)" "unprognostic (4.68e-2)" "unprognostic (1.56e-2)" "unprognostic (1.61e-2)" "unprognostic (3.16e-1)" "unprognostic (1.21e-1)" "unprognostic (5.05e-2)" "unprognostic (4.81e-2)" "unprognostic (5.25e-2)" "unprognostic (9.20e-3)" "prognostic unfavorable (8.87e-4)" "unprognostic (4.08e-1)" "unprognostic (7.16e-2)" "unprognostic (1.39e-2)" 16.7 4.1 7.7 5.3 8.6 7.2 11.2 16.6 15.5 2.8 0.5 2.8 2.9 3.8 3.8 4.3 2.3 5.1 7.2 6.7 1.7 4.5 4.6 5.1 5.2 1.6 2.3 2.8 2.2 3.9 1.5 10.8 2.9 3.8 2.8 10.5 8.8 2.9 6.0 6.3 3.4 5.1 0.4 5.0 7.3 6.0 3.9 3.2 4.2 5.0 4.1 5.1 2.5 13.7 6.3 2.4 2.5 2.1 12.5 7.1 3.7 5.3 1.2 1.0 1.6 1.9 7.9 41.3 4.9 2.9 3.5 3.1 3.9 5.5 1.8 19.7 6.6 4.4 6.4 3.4 7.4 10.3 2.7 7.8 8.7 1.5 9.1 2.0 28.0 5.8 8.4 19.6 3.1 6.5 3.8 7.4 3.2 10.3 5.9 8.6 4.2 8.5 4.2 6.1 4.6 3.8 5.0 9.0 2.7 3.6 6.5 4.4 17.9 3.2 9.7 2.1 1.9 8.2 11.3 19.1 7.3 5.1 4.1 2.8 0.6 0.6 0.5 0.5 0.4 0.6 0.5 0.4 0.3 0.9 0.5 0.6 1.5 0.6 0.6 1.0 0.6 0.3 7.7 8.6 16.6 15.5 6.7 1.7 1.6 2.3 2.9 0.4 3.9 13.7 272.0 60.9 69.9 0.0 4.9 0.0 0.0 0.0 0.0 0.0 87.0 42.2 0.0 0.0 36.5 33.1 0.0 1.6 9.2 0.0 7.9 12.0 0.0 4.6 3.9 44.0 0.0 0.0 0.0 17.3 2.8 13.8 0.0 12.0 32.8 0.4 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 4.6 0.0 0.0 0.0 0.0 28.2 0.0 0.0 4.0 0.0 0.0 3.5 42.3 0.0 0.0 0.0 36.5 0.0 0.0 0.0 0.0 2.5 9.8 1.3 0.0 0.0 FAM83A "BJ-TSA-9, MGC14128" ENSG00000147689 "Family with sequence similarity 83 member A" Q86UY5 8 123178960-123210079 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 111.3;vagina: 55.8" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 71.2;Club cells: 58.2;Pancreatic endocrine cells: 28.7;Squamous epithelial cells: 19.3;Suprabasal keratinocytes: 15.2;Urothelial cells: 25.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 52.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "A-431: 83.5;HBEC3-KT: 126.3;hTCEpi: 66.4;K-562: 206.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA052615 Approved Nucleoplasm,Cytosol NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm Cytosol "HPA052615: AB_2797244" "unprognostic (4.48e-2)" "unprognostic (2.03e-3)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.85e-4)" "unprognostic (2.49e-1)" "unprognostic (2.68e-1)" "unprognostic (8.67e-2)" "prognostic unfavorable (2.98e-9)" "unprognostic (2.62e-1)" "unprognostic (2.81e-1)" "prognostic unfavorable (4.99e-6)" "unprognostic (2.04e-1)" "unprognostic (2.22e-16)" "unprognostic (2.76e-1)" "unprognostic (1.33e-2)" "unprognostic (2.24e-1)" "unprognostic (6.07e-2)" 0.2 0.6 0.0 0.1 0.0 0.2 0.3 0.2 0.1 18.9 0.1 0.1 1.0 0.0 1.3 111.3 4.3 1.0 0.0 0.0 0.0 0.2 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.7 0.0 0.1 7.5 6.4 0.1 10.2 2.4 0.0 0.0 0.1 0.1 0.6 0.0 0.1 0.4 0.0 7.4 3.8 55.8 0.0 83.5 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 1.6 0.7 10.6 0.0 0.0 25.9 0.0 126.3 0.0 0.0 0.1 0.8 9.2 0.0 0.0 0.1 0.1 0.0 66.4 0.0 16.8 0.0 0.0 0.1 206.3 0.1 0.0 0.3 0.0 0.1 0.0 4.2 0.1 0.0 0.0 0.1 0.0 18.4 0.1 0.0 14.4 9.7 0.1 0.2 1.5 0.2 0.6 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 4.0 71.2 1.2 0.0 4.4 0.9 1.1 0.0 58.2 1.8 0.0 0.1 0.0 1.0 0.0 0.3 1.0 0.0 0.1 0.1 0.0 0.0 0.6 0.7 0.0 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.1 10.2 0.0 0.4 1.6 0.3 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 28.7 0.2 0.0 0.1 0.7 1.1 0.1 9.6 0.0 0.0 0.1 1.4 2.2 0.6 19.3 15.2 0.0 0.1 0.0 0.8 25.0 FAM83B "C6orf143, FLJ30642" ENSG00000168143 "Family with sequence similarity 83 member B" Q5T0W9 6 54846771-54945099 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 14.5;skin 1: 25.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 33.8;Basal prostatic cells: 32.5;Basal squamous epithelial cells: 43.3;Squamous epithelial cells: 31.9;Suprabasal keratinocytes: 41.1;Urothelial cells: 25.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 15.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 13.3;HaCaT: 18.1;HBEC3-KT: 9.8;hTCEpi: 19.7;hTERT-HME1: 23.8;RT4: 19.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA031464, HPA031465" Enhanced NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "HPA031464: AB_10599973, HPA031465: AB_10601566" "unprognostic (2.29e-1)" "unprognostic (3.93e-2)" "unprognostic (3.71e-2)" "unprognostic (1.03e-2)" "unprognostic (1.71e-2)" "prognostic unfavorable (1.48e-4)" "unprognostic (7.27e-2)" "unprognostic (5.77e-3)" "prognostic unfavorable (7.60e-4)" "unprognostic (1.62e-1)" "unprognostic (3.19e-2)" "unprognostic (1.85e-1)" "unprognostic (4.35e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (1.86e-5)" 0.0 0.0 0.1 1.0 0.1 0.1 2.2 0.1 0.1 3.8 0.0 8.0 7.4 0.3 1.2 14.5 1.6 2.1 1.1 0.0 0.0 2.5 0.1 0.1 0.0 0.0 0.7 0.0 1.5 0.0 0.0 4.3 0.1 1.8 8.2 0.1 4.7 1.1 0.7 25.9 7.4 0.2 0.0 0.0 3.9 0.6 0.0 2.3 3.6 0.1 3.6 4.3 9.8 0.2 13.3 0.2 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 6.5 3.6 0.0 0.0 0.0 0.1 18.1 0.0 9.8 0.1 0.0 2.2 0.0 2.5 0.0 0.0 0.0 0.0 0.0 19.7 0.0 23.8 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.6 4.1 0.0 0.0 0.0 0.0 9.1 19.2 0.2 0.0 2.9 0.6 0.0 3.3 4.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 33.8 32.5 6.6 43.3 0.0 1.5 3.0 3.1 5.7 6.5 7.3 0.0 11.2 0.1 9.0 0.0 6.1 6.3 8.8 0.8 0.3 1.2 0.0 0.2 3.5 11.9 0.4 9.2 8.1 0.0 0.0 0.4 0.0 0.6 0.0 0.1 5.4 6.1 0.0 1.5 2.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 17.4 0.0 0.1 9.1 12.6 0.0 1.8 0.0 0.0 0.0 0.1 0.1 0.6 31.9 41.1 18.7 0.1 0.0 8.8 25.4 FGFR1 "BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM" ENSG00000077782 "Fibroblast growth factor receptor 1" P11362 8 38400215-38468834 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Transcription, Transcription regulation" "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Dwarfism, FDA approved drug targets, Holoprosencephaly, Hypogonadotropic hypogonadism, Kallmann syndrome, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 176.7;Leydig cells: 192.0;Oligodendrocyte precursor cells: 166.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AN3-CA: 508.7;BJ hTERT+: 278.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033614, HPA056402" Approved NA NA 78000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "CAB033614: AB_783377, HPA056402: AB_2683118" "unprognostic (9.53e-2)" "unprognostic (7.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.35e-2)" "unprognostic (4.23e-3)" "unprognostic (7.02e-2)" "unprognostic (6.59e-2)" "unprognostic (2.77e-1)" "unprognostic (1.81e-1)" "unprognostic (3.99e-2)" "unprognostic (7.97e-3)" "unprognostic (4.59e-2)" "unprognostic (7.69e-2)" "unprognostic (6.87e-3)" "unprognostic (5.60e-2)" "unprognostic (4.59e-3)" "unprognostic (1.05e-3)" 95.1 12.8 27.5 15.9 24.6 14.1 87.1 48.8 22.4 79.8 37.2 97.2 8.8 74.2 15.8 35.8 85.9 57.1 89.9 30.9 28.8 40.1 9.1 55.7 16.6 35.9 37.3 108.2 98.6 20.4 57.1 51.3 63.7 60.5 17.9 15.8 31.4 53.6 24.8 35.6 41.7 57.1 30.3 9.9 40.4 20.4 33.4 17.1 33.7 23.3 16.1 79.3 63.9 29.6 12.9 42.0 198.0 508.7 120.1 91.2 142.9 136.7 278.8 90.0 95.8 27.3 6.5 1.8 38.3 127.7 103.9 0.2 90.0 6.8 104.3 39.2 24.1 0.0 7.7 27.8 69.7 31.1 0.6 80.5 0.7 70.9 13.3 45.6 86.9 6.0 11.9 0.4 40.5 12.5 91.5 9.2 145.9 1.6 21.6 86.3 21.1 0.4 35.6 0.3 7.9 19.4 23.4 1.0 5.1 93.4 9.3 5.4 51.4 49.2 28.9 149.6 29.7 2.4 4.1 0.5 60.3 1.7 27.1 0.2 0.3 0.1 1.7 0.1 1.1 0.3 0.7 1.2 0.0 0.6 0.5 1.5 0.6 0.4 0.2 0.2 1.0 0.1 27.5 24.6 48.8 22.4 30.9 28.8 35.9 37.3 63.7 30.3 33.4 29.6 101.0 3.2 15.8 55.8 1.8 31.5 95.9 1.1 37.0 4.4 28.7 77.7 52.5 24.3 5.1 9.2 4.2 8.3 6.3 0.4 0.0 27.3 15.3 48.2 40.6 75.5 25.0 3.6 25.4 65.2 80.5 176.7 3.1 75.3 8.2 40.4 47.5 0.8 25.3 21.9 21.1 0.6 4.1 5.6 75.2 15.0 192.0 11.7 33.8 19.7 1.7 88.1 6.2 166.4 14.2 21.6 0.3 99.6 6.4 94.7 0.1 7.9 1.0 3.3 13.1 118.9 59.9 1.6 14.1 4.8 19.7 10.4 14.1 2.1 0.7 11.7 FKBP1A "FKBP-12, FKBP1, FKBP12, FKBP12C, PKC12, PPIASE" ENSG00000088832 "FKBP prolyl isomerase 1A" P62942 20 1368977-1393164 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Paneth cells: 977.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 675.2;granulocytes: 974.2;monocytes: 1013.4" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 1749.2;TIME: 1929.6" "CAB004639, HPA051798" Uncertain NA NA 12000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004639: AB_425434, HPA051798: AB_2681615" "unprognostic (4.09e-2)" "unprognostic (2.29e-1)" "unprognostic (5.22e-3)" "unprognostic (1.28e-2)" "unprognostic (2.66e-1)" "unprognostic (7.18e-3)" "prognostic unfavorable (3.44e-7)" "unprognostic (7.05e-3)" "unprognostic (2.76e-1)" "unprognostic (8.81e-2)" "unprognostic (5.12e-3)" "unprognostic (6.65e-2)" "prognostic unfavorable (6.69e-5)" "unprognostic (1.97e-2)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" 272.7 185.0 138.4 178.8 177.5 167.0 188.2 88.5 163.2 123.0 112.6 158.6 108.9 165.4 150.1 169.8 131.7 104.5 171.4 166.7 115.8 186.7 98.1 235.2 162.7 92.4 98.9 135.1 114.6 123.0 79.5 218.7 95.6 125.4 188.5 11.8 111.0 119.8 110.3 127.3 117.0 225.1 97.8 185.7 118.3 56.9 120.5 188.1 190.9 150.6 202.2 206.8 126.2 118.9 718.1 299.5 172.9 240.3 654.1 771.3 202.9 423.9 337.1 382.7 354.2 278.4 295.2 272.5 149.3 555.7 656.3 337.7 255.1 1007.2 419.7 68.8 170.5 284.2 113.9 473.3 406.4 390.5 168.0 484.7 332.0 410.3 412.6 513.3 1749.2 401.0 271.0 145.8 443.3 125.8 401.9 453.7 307.1 335.3 276.4 307.0 254.1 351.9 540.0 243.4 248.7 173.8 208.0 479.3 728.8 231.8 177.2 293.0 1929.6 1363.6 201.8 278.1 329.5 76.4 168.1 292.9 248.1 332.3 307.5 316.3 870.8 974.2 112.9 1005.8 104.3 128.1 135.5 133.2 675.2 136.2 140.1 132.6 805.0 160.6 1013.4 312.7 195.0 1153.8 138.4 177.5 88.5 163.2 166.7 115.8 92.4 98.9 95.6 97.8 120.5 118.9 779.1 86.6 77.2 0.0 160.6 263.1 211.2 393.3 152.0 17.6 175.6 156.5 59.7 170.1 179.5 172.9 0.0 281.8 148.3 456.2 238.7 432.4 47.7 98.7 183.8 814.8 330.6 196.4 0.0 337.5 702.0 212.2 160.0 122.5 143.5 95.3 623.6 113.5 746.7 35.3 0.0 245.9 329.6 541.8 436.5 52.2 200.0 428.8 241.9 0.0 527.4 52.2 152.4 0.0 0.0 483.6 977.5 162.9 214.8 221.1 210.8 332.1 123.0 11.7 138.1 87.4 224.7 169.3 141.8 329.4 299.3 231.5 150.1 347.3 318.0 245.7 FLT4 "PCL, VEGFR-3, VEGFR3" ENSG00000037280 "Fms related receptor tyrosine kinase 4" P35916 5 180601506-180649624 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 27.4;Endothelial cells: 27.1;Extravillous trophoblasts: 37.1;Hepatic stellate cells: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 3.8" "Lineage enriched" "Detected in single" 31 "T-cells: 3.8" "Cell line enhanced" "Detected in some" "AN3-CA: 10.1;BEWO: 12.4;HEK 293: 15.6;HL-60: 9.5;HUVEC TERT2: 9.9;JURKAT: 12.3;T-47d: 14.6;TIME: 15.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000099, HPA046519, HPA067906, HPA074389" Approved Supported "Nuclear speckles,Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 20000000 290000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles, Plasma membrane" "Cell Junctions" "CAB000099: , HPA046519: AB_2732527, HPA067906: AB_2732775, HPA074389: " "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" "unprognostic (9.45e-3)" "unprognostic (3.81e-1)" "unprognostic (9.26e-2)" "unprognostic (3.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-1)" "unprognostic (1.88e-2)" "unprognostic (9.41e-3)" "unprognostic (1.83e-1)" "unprognostic (8.26e-2)" "unprognostic (1.32e-1)" 17.2 11.3 3.5 4.7 4.6 0.8 14.7 2.6 3.4 9.0 2.6 4.9 2.8 8.0 3.0 4.4 9.8 3.8 9.7 5.1 2.6 20.1 6.2 16.9 5.5 3.4 3.0 4.5 2.0 2.3 7.8 6.4 3.6 5.6 1.3 0.3 2.0 2.5 4.7 4.0 7.2 4.1 2.8 17.6 3.5 3.1 4.2 1.0 25.7 4.1 1.4 5.6 5.5 2.7 0.1 2.5 3.2 10.1 0.0 0.0 12.4 0.3 0.1 0.0 0.0 0.4 0.3 0.3 0.9 0.1 0.6 0.4 3.4 0.2 0.3 0.1 15.6 1.2 0.5 0.5 0.1 9.5 0.3 0.2 0.1 0.2 0.4 0.3 9.9 12.3 0.4 0.4 2.1 5.6 0.1 0.5 7.0 0.3 0.6 8.2 0.1 0.1 0.1 0.3 0.3 1.1 0.1 0.2 0.1 3.1 14.6 0.3 15.7 0.2 6.9 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.5 0.0 3.8 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 3.5 4.6 2.6 3.4 5.1 2.6 3.4 3.0 3.6 2.8 4.2 2.7 27.4 0.0 1.7 0.7 0.7 0.9 0.2 0.0 1.2 0.2 1.4 1.4 4.5 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.1 27.1 0.0 0.0 0.2 0.0 37.1 0.8 0.0 0.1 2.5 2.4 64.6 0.6 1.2 0.0 0.1 0.0 0.0 3.3 0.8 0.7 0.3 0.6 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.7 0.7 0.1 5.2 0.1 1.1 1.0 1.8 0.2 0.0 0.1 GALNT15 "GALNT7, GALNTL2, pp-GalNAc-T15" ENSG00000131386 "Polypeptide N-acetylgalactosaminyltransferase 15" Q8N3T1 3 16174680-16231992 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 157.4;brain: 141.7" "Cell type enhanced" "Detected in many" "Adipocytes: 103.9;Astrocytes: 34.6;Early spermatids: 26.6;Endothelial cells: 26.9;Hepatic stellate cells: 41.7;Muller glia cells: 47.4;Oligodendrocytes: 69.3" "Cancer enriched" "Detected in many" 5 "glioma: 21.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "ASC diff: 133.0;ASC TERT1: 128.8;HSkMC: 102.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017076 Uncertain Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 40000 "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" Cytosol "HPA017076: AB_1849458" "unprognostic (3.87e-1)" "unprognostic (4.84e-4)" "unprognostic (6.39e-2)" "unprognostic (8.77e-3)" "unprognostic (2.77e-1)" "unprognostic (2.52e-1)" "unprognostic (7.40e-4)" "unprognostic (4.24e-1)" "unprognostic (2.24e-1)" "unprognostic (8.28e-6)" "unprognostic (5.13e-2)" "unprognostic (2.58e-1)" "unprognostic (2.66e-2)" "unprognostic (1.37e-3)" "unprognostic (1.88e-1)" "unprognostic (8.51e-2)" "unprognostic (1.78e-3)" 157.4 4.9 45.1 1.7 55.8 2.7 87.2 62.5 49.3 12.3 14.4 21.7 3.0 11.4 11.9 12.4 24.9 5.6 18.1 47.9 90.8 11.8 4.0 9.4 4.1 137.6 60.4 22.3 3.6 2.4 3.5 32.3 130.8 6.0 3.9 13.4 25.5 4.7 36.3 41.7 21.2 7.0 102.4 12.3 15.3 9.1 62.8 4.0 18.3 35.3 1.3 33.0 22.8 141.7 0.4 1.3 0.9 1.0 133.0 128.8 0.3 3.4 2.5 0.4 1.3 0.0 0.5 0.5 1.9 7.8 2.3 0.8 0.5 1.4 2.0 0.6 1.4 1.1 1.9 0.0 7.4 1.5 0.4 102.8 0.0 1.2 1.8 2.4 2.8 0.7 0.2 3.0 1.1 1.9 0.0 2.1 0.5 0.8 1.1 0.3 1.1 24.1 0.5 0.5 0.4 0.3 0.4 1.0 0.6 0.6 0.7 1.8 3.9 0.6 4.3 26.8 0.6 1.4 5.1 1.4 2.5 0.4 0.4 0.5 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.2 0.1 0.2 0.1 0.3 0.1 0.0 45.1 55.8 62.5 49.3 47.9 90.8 137.6 60.4 130.8 102.4 62.8 141.7 103.9 0.0 1.7 34.6 0.1 0.5 0.4 0.0 0.0 3.8 1.1 0.9 2.8 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 26.6 0.5 3.3 26.9 0.0 0.0 4.9 0.0 0.1 24.7 0.0 1.0 1.3 0.1 41.7 1.8 0.1 0.0 3.9 0.0 0.0 0.8 2.1 16.7 1.8 0.5 0.0 22.5 0.1 47.4 0.0 5.0 69.3 0.2 0.0 0.7 1.8 2.1 0.0 0.1 0.0 3.2 0.0 7.3 2.1 25.5 0.5 0.1 0.9 0.0 0.2 0.3 0.0 0.3 GBP4 Mpa2 ENSG00000162654 "Guanylate binding protein 4" Q96PP9 1 89181144-89198942 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 84.4;Endothelial cells: 81.2;Hepatic stellate cells: 92.4;Theca cells: 122.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "CAPAN-2: 12.1;HDLM-2: 9.9;HEL: 13.0;REH: 11.1;RT4: 18.3;U-266/70: 16.0" "HPA030101, HPA062039" Enhanced Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 15: RT4 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "Plasma membrane" "HPA030101: AB_10601654, HPA062039: " "unprognostic (1.32e-2)" "unprognostic (3.89e-3)" "unprognostic (1.02e-2)" "unprognostic (1.07e-3)" "unprognostic (3.22e-1)" "unprognostic (9.93e-3)" "unprognostic (5.65e-2)" "unprognostic (1.09e-1)" "unprognostic (3.22e-1)" "prognostic favorable (9.29e-5)" "unprognostic (1.91e-3)" "unprognostic (3.38e-1)" "prognostic unfavorable (1.30e-5)" "unprognostic (1.22e-1)" "unprognostic (3.91e-2)" "unprognostic (2.68e-2)" "unprognostic (2.02e-3)" 11.3 5.2 4.0 29.5 3.9 6.6 6.7 4.4 4.8 4.2 2.6 6.6 12.4 8.8 4.5 7.2 9.1 8.8 11.0 3.8 4.3 9.8 14.1 31.2 34.3 7.1 3.7 16.4 1.6 6.5 2.7 11.9 7.7 5.8 7.2 3.4 7.1 6.7 7.1 2.1 11.8 7.7 3.9 29.0 11.9 2.9 4.4 10.0 7.8 9.4 11.0 13.1 4.5 3.9 0.8 0.0 0.1 0.3 0.1 0.1 0.6 1.8 7.6 8.0 7.2 0.1 12.1 0.6 1.0 2.3 0.6 0.9 0.0 0.3 0.4 9.9 0.1 13.0 0.4 0.3 1.0 0.2 0.3 0.4 0.0 0.1 0.0 1.2 1.9 0.3 0.4 2.3 0.0 0.2 6.6 0.3 0.4 0.1 0.1 11.1 0.2 0.4 0.1 18.3 0.2 0.5 0.3 0.7 0.3 0.6 0.5 1.4 0.4 0.3 1.6 0.2 0.2 16.0 0.3 0.3 0.3 0.1 2.3 0.6 4.1 0.4 7.1 14.1 6.1 2.5 7.6 7.9 2.2 3.3 5.6 5.2 5.6 13.8 14.5 0.9 9.0 5.5 4.0 3.9 4.4 4.8 3.8 4.3 7.1 3.7 7.7 3.9 4.4 3.9 84.4 32.1 39.3 0.0 28.3 4.6 9.1 20.7 1.8 2.8 3.5 2.4 3.6 8.6 25.3 5.5 8.4 0.9 29.0 5.1 0.0 2.2 1.9 4.8 8.4 81.2 0.0 11.2 0.5 3.3 1.6 22.2 9.2 7.4 21.5 17.9 92.4 6.5 8.3 0.0 2.5 4.3 4.1 29.2 10.9 1.2 3.7 33.7 5.4 15.9 33.8 15.5 36.0 1.0 0.6 36.3 1.9 1.9 7.2 24.4 4.4 1.5 43.3 12.2 0.0 5.3 11.3 2.4 3.4 2.9 3.0 1.5 34.2 122.6 2.4 13.6 GDF3 ENSG00000184344 "Growth differentiation factor 3" Q9NR23 12 7689784-7695775 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Developmental protein, Growth factor" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "kidney: 2.9" "Cell type enriched" "Detected in some" 25 "Granulosa cells: 30.2" "Cancer enriched" "Detected in some" 422 "testis cancer: 383.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "NTERA-2: 452.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA018468 Uncertain "Secreted to blood" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 40: Granulosa cells - Unknown function" "HPA018468: AB_1849586" "unprognostic (9.48e-2)" "unprognostic (3.90e-2)" "unprognostic (3.30e-2)" "unprognostic (1.86e-2)" "unprognostic (3.51e-1)" "unprognostic (5.40e-2)" "unprognostic (3.09e-1)" "unprognostic (2.08e-1)" "unprognostic (2.89e-1)" "unprognostic (1.07e-1)" "unprognostic (9.20e-2)" "unprognostic (1.25e-3)" "unprognostic (8.00e-3)" "unprognostic (1.00e-1)" "unprognostic (2.45e-1)" "unprognostic (2.03e-1)" 0.3 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 2.9 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.9 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 36.8 0.0 0.0 0.0 0.6 2.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.2 0.0 0.0 0.0 0.1 0.0 452.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 77.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 30.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GIMAP4 "FLJ11110, HIMAP4, IAN1, IMAP4" ENSG00000133574 "GTPase, IMAP family member 4" Q9NUV9 7 150567369-150573953 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 127.7" "Cell type enhanced" "Detected in many" "Adipocytes: 182.3;Endothelial cells: 195.2;Hepatic stellate cells: 222.0;Kupffer cells: 197.2;Macrophages: 110.0;monocytes: 176.0;NK-cells: 344.0;T-cells: 186.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 26 "HUVEC TERT2: 326.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019135, HPA019137, HPA027198" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Vesicles, Cytosol" "HPA019135: AB_1849670, HPA019137: AB_1849672, HPA027198: AB_10602599" "unprognostic (5.03e-2)" "unprognostic (3.30e-3)" "unprognostic (4.08e-2)" "prognostic favorable (7.63e-4)" "unprognostic (1.72e-1)" "unprognostic (1.73e-2)" "unprognostic (7.00e-2)" "unprognostic (2.40e-2)" "unprognostic (1.87e-2)" "unprognostic (1.05e-1)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.65e-1)" "unprognostic (3.32e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-1)" 46.1 18.3 15.0 75.1 15.6 4.2 31.8 16.2 21.2 19.7 16.3 21.2 16.5 23.0 9.6 12.0 18.7 24.6 31.3 14.3 16.0 17.3 29.9 50.8 127.7 19.2 18.0 7.7 6.7 9.6 6.0 48.7 18.0 10.2 22.4 1.5 11.2 13.3 17.5 8.4 25.0 38.3 18.8 115.6 18.0 4.2 16.4 30.5 21.1 48.1 85.1 31.1 11.6 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 326.4 3.4 0.1 0.3 0.0 0.0 0.4 0.2 0.4 0.0 0.0 12.7 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.5 370.2 5.2 325.8 390.9 404.2 3.0 408.0 402.8 122.1 1.3 424.3 361.9 339.7 263.4 320.4 5.3 312.1 776.9 15.0 15.6 16.2 21.2 14.3 16.0 19.2 18.0 18.0 18.8 16.4 18.7 182.3 3.2 12.4 0.3 7.3 6.8 0.2 0.0 3.4 0.1 2.2 4.7 9.9 5.7 1.8 11.0 0.0 0.6 82.6 0.0 0.0 0.2 0.6 0.3 0.4 195.2 0.0 9.7 0.5 0.2 0.8 9.0 2.0 0.3 6.3 0.0 222.0 3.7 96.4 0.0 0.1 0.0 0.0 197.2 20.9 1.7 5.0 110.0 10.6 18.7 176.0 0.2 344.0 0.0 0.1 0.1 0.0 0.0 14.7 0.4 0.0 1.9 0.7 0.4 13.1 3.9 7.9 0.0 0.8 1.1 6.1 0.8 186.2 0.8 0.0 0.3 GIMAP5 "HIMAP3, IAN4L1, IAN5" ENSG00000196329 "GTPase, IMAP family member 5" Q96F15 7 150722253-150750033 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 106.2" "Cell type enhanced" "Detected in some" "Adipocytes: 22.1;Basal keratinocytes: 11.1;Endothelial cells: 29.7;Langerhans cells: 13.9;Suprabasal keratinocytes: 10.7;T-cells: 31.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 5 "MOLT-4: 41.7" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.77e-2)" "unprognostic (8.83e-3)" "unprognostic (1.61e-1)" "unprognostic (4.68e-2)" "unprognostic (2.49e-1)" "unprognostic (2.34e-3)" "unprognostic (2.21e-3)" "unprognostic (6.42e-2)" "unprognostic (2.12e-1)" "unprognostic (1.61e-2)" "unprognostic (2.96e-2)" "unprognostic (9.87e-2)" "unprognostic (2.77e-3)" "unprognostic (4.13e-1)" "unprognostic (7.15e-3)" "unprognostic (1.86e-1)" "unprognostic (1.47e-2)" 34.4 13.6 13.3 44.8 14.2 5.2 25.5 13.7 16.8 15.9 12.7 16.6 10.6 17.1 8.8 12.4 18.9 17.9 24.2 12.8 13.2 12.7 23.3 39.7 106.2 15.2 14.1 5.9 8.7 9.1 4.1 26.4 14.8 6.6 16.5 0.8 7.2 9.0 12.4 7.2 22.1 30.5 14.2 64.2 15.6 3.5 14.7 25.1 18.3 43.9 66.4 26.7 6.7 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.9 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 3.3 0.0 1.4 0.0 0.0 41.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 4.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.4 0.0 3.6 70.5 1.1 260.4 106.3 337.2 1.1 436.3 334.0 8.0 0.6 521.5 280.6 8.3 188.3 43.6 1.6 176.9 510.2 13.3 14.2 13.7 16.8 12.8 13.2 15.2 14.1 14.8 14.2 14.7 13.8 22.1 0.0 1.7 0.0 1.4 11.1 0.3 0.0 1.2 0.1 0.2 0.1 0.8 0.0 0.0 0.0 0.0 0.1 5.8 0.2 0.0 0.0 0.1 0.0 0.1 29.7 0.0 0.4 0.0 0.0 0.4 2.6 0.5 0.1 2.5 0.0 8.9 0.6 3.1 0.0 0.0 0.2 0.0 5.3 13.9 0.1 0.0 7.1 3.6 0.0 2.2 0.0 9.2 0.0 0.0 0.0 0.0 0.0 3.0 0.3 0.1 0.1 0.0 0.1 0.0 0.7 3.2 0.2 0.1 0.1 10.7 0.3 31.5 0.1 0.1 0.1 GIMAP6 "FLJ22690, IAN6" ENSG00000133561 "GTPase, IMAP family member 6" Q6P9H5 7 150625375-150632648 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 95.3;Endothelial cells: 83.5;Hepatic stellate cells: 92.1;Kupffer cells: 75.2;monocytes: 37.4;NK-cells: 91.6;T-cells: 41.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "monocytes: 75.1;NK-cells: 217.3;T-cells: 127.2" "Cell line enhanced" "Detected in some" "HMC-1: 18.4;HUVEC TERT2: 124.9;MOLT-4: 43.3;TIME: 35.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026715, HPA050740" Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA026715: AB_1849675, HPA050740: AB_2797239" "unprognostic (8.58e-2)" "unprognostic (1.34e-2)" "unprognostic (6.56e-3)" "prognostic favorable (3.12e-4)" "unprognostic (1.22e-1)" "prognostic favorable (2.91e-4)" "prognostic favorable (1.56e-4)" "unprognostic (2.88e-2)" "unprognostic (8.75e-2)" "unprognostic (8.87e-2)" "unprognostic (4.68e-2)" "unprognostic (3.52e-1)" "prognostic unfavorable (5.27e-4)" "unprognostic (2.75e-1)" "unprognostic (2.48e-2)" "unprognostic (3.01e-1)" "unprognostic (1.27e-1)" 42.0 9.4 9.7 33.9 9.7 2.5 21.8 9.7 10.6 14.9 8.0 12.0 13.6 19.3 7.3 8.4 16.9 14.7 29.1 8.0 9.5 12.4 12.7 38.8 50.2 11.4 10.5 5.7 5.2 8.0 3.3 32.3 11.3 6.4 12.2 0.6 7.8 10.0 24.7 6.4 18.7 25.8 10.9 64.0 11.6 3.2 11.6 29.3 14.2 34.7 33.9 16.5 6.5 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 3.8 0.0 6.3 0.0 0.0 0.0 0.4 18.4 0.1 0.0 0.0 0.0 0.0 124.9 0.5 0.0 4.6 0.0 0.0 43.3 5.4 0.0 0.0 0.0 4.6 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.8 35.9 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 13.0 0.0 11.6 58.1 2.1 112.9 75.1 127.2 0.4 104.3 120.2 22.1 0.3 108.3 103.0 8.0 217.3 60.2 0.7 105.7 163.5 9.7 9.7 9.7 10.6 8.0 9.5 11.4 10.5 11.3 10.9 11.6 10.1 95.3 0.0 1.1 0.0 3.1 3.8 0.1 0.0 0.6 0.0 1.1 1.0 7.4 0.0 0.0 0.0 0.0 0.2 24.5 0.1 0.0 0.0 0.4 0.1 0.2 83.5 0.0 19.4 0.0 0.2 0.3 3.4 0.0 0.2 2.5 0.3 92.1 1.7 30.6 0.0 0.0 0.1 0.0 75.2 6.5 2.2 1.2 20.0 1.8 13.1 37.4 0.1 91.6 0.0 0.1 0.1 0.0 0.0 2.9 0.1 0.0 0.2 0.7 0.4 0.0 2.6 2.2 0.3 0.1 0.4 3.1 0.4 41.2 1.2 0.0 0.3 GIMAP8 "DKFZp667I133, hIAN6, IAN9" ENSG00000171115 "GTPase, IMAP family member 8" Q8ND71 7 150450630-150479393 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.6" "Cell type enhanced" "Detected in many" "Adipocytes: 67.4;Endothelial cells: 66.0;Hepatic stellate cells: 86.0;Kupffer cells: 75.1;Microglial cells: 32.8;monocytes: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 6 "HUVEC TERT2: 59.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA014474, HPA017765" Supported NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA014474: AB_1849685, HPA017765: AB_1849683" "unprognostic (7.86e-2)" "unprognostic (7.87e-3)" "unprognostic (1.04e-1)" "unprognostic (4.42e-3)" "unprognostic (2.11e-1)" "unprognostic (8.09e-3)" "unprognostic (1.07e-3)" "unprognostic (1.32e-2)" "unprognostic (1.58e-1)" "unprognostic (8.07e-2)" "unprognostic (6.26e-3)" "unprognostic (2.15e-1)" "unprognostic (1.04e-3)" "unprognostic (2.01e-1)" "prognostic unfavorable (8.47e-4)" "unprognostic (3.85e-1)" "unprognostic (1.31e-1)" 20.3 5.7 4.4 21.3 5.0 0.7 16.0 4.7 5.5 9.8 5.5 6.7 6.8 10.4 3.1 4.3 9.0 7.5 17.4 4.1 4.5 8.3 9.4 27.0 23.2 5.4 4.9 3.5 2.8 4.6 2.6 15.4 5.4 4.9 7.2 0.3 4.3 5.3 9.8 4.7 10.5 12.7 5.4 40.6 5.0 2.0 5.1 7.3 11.9 15.1 13.5 8.4 5.6 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.0 59.1 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.7 0.0 9.4 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.5 45.2 0.0 15.3 59.0 17.4 0.5 14.8 13.9 13.0 0.0 16.7 13.6 4.8 15.5 57.4 0.7 7.7 26.8 4.4 5.0 4.7 5.5 4.1 4.5 5.4 4.9 5.4 5.4 5.1 5.8 67.4 3.2 5.3 0.3 0.8 3.1 0.5 0.0 1.8 0.0 0.4 0.8 5.5 5.7 0.0 1.8 0.0 0.0 5.3 0.0 0.0 0.0 0.3 0.2 0.1 66.0 0.0 1.3 0.1 0.0 0.0 2.3 0.5 0.2 3.8 0.0 86.0 1.6 6.8 0.0 0.1 0.0 0.0 75.1 2.8 0.9 0.3 21.9 0.0 32.8 44.2 0.0 19.6 0.0 0.1 0.0 0.0 0.0 2.2 0.9 0.0 0.2 1.5 0.0 0.0 1.5 1.2 0.2 0.4 0.5 1.7 0.1 11.1 0.2 0.0 0.4 GNA14 ENSG00000156049 "G protein subunit alpha 14" O95837 9 77423079-77648322 "Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 219.1;Early spermatids: 50.2;Hepatic stellate cells: 61.4;Late spermatids: 38.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 95 "basophil: 27.3" "Lineage enriched" "Detected in single" 95 "granulocytes: 27.3" "Cell line enhanced" "Detected in some" "BJ hTERT+: 2.3;HUVEC TERT2: 1.6;PC-3: 3.2;THP-1: 1.6;U-2197: 2.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA048886 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA048886: AB_2680544" "unprognostic (7.80e-3)" "unprognostic (1.10e-2)" "unprognostic (1.09e-2)" "unprognostic (1.18e-3)" "unprognostic (2.03e-1)" "unprognostic (1.53e-4)" "unprognostic (2.48e-6)" "unprognostic (6.35e-3)" "unprognostic (3.34e-1)" "unprognostic (9.04e-2)" "unprognostic (1.21e-1)" "unprognostic (2.43e-1)" "unprognostic (2.92e-2)" "unprognostic (1.04e-3)" "unprognostic (1.79e-1)" "unprognostic (1.75e-3)" "unprognostic (2.03e-1)" 3.4 2.2 7.3 4.0 6.5 0.0 2.4 2.7 8.4 3.6 11.8 5.8 1.7 15.6 5.2 4.8 3.6 4.9 4.1 9.2 4.5 11.7 6.0 8.8 3.3 9.7 5.0 6.0 1.4 1.4 3.1 7.0 7.0 6.8 6.1 0.1 8.0 13.7 0.6 0.9 3.0 13.8 8.1 7.3 3.3 2.1 5.6 0.7 17.6 0.6 2.1 7.6 4.8 13.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.3 1.0 0.3 0.0 0.6 0.0 0.9 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.9 0.4 3.2 0.0 0.0 0.0 0.0 1.2 0.1 0.1 0.8 0.4 0.0 1.2 0.3 1.6 0.4 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 27.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 7.3 6.5 2.7 8.4 9.2 4.5 9.7 5.0 7.0 8.1 5.6 13.9 2.3 0.0 1.1 219.1 0.2 0.6 2.0 0.2 0.0 0.0 1.0 0.4 0.8 0.0 6.5 0.0 0.0 0.1 0.0 2.6 0.0 0.7 50.2 1.7 4.9 12.8 3.0 2.7 15.8 1.0 0.1 4.2 0.0 1.8 4.5 0.1 61.4 1.2 0.3 0.0 4.4 13.7 2.0 2.5 1.1 38.8 3.7 0.2 1.8 15.9 0.0 0.0 0.0 7.1 12.4 0.1 2.7 1.9 0.0 1.0 0.5 7.1 20.8 0.0 0.0 19.4 0.9 0.4 0.7 0.3 0.6 0.1 0.2 0.5 2.9 4.9 GNG11 GNGT11 ENSG00000127920 "G protein subunit gamma 11" P61952 7 93921735-93928610 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Adipocytes: 1903.6;Endothelial cells: 1236.2;Hepatic stellate cells: 994.2;Macrophages: 481.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 20.5;neutrophil: 9.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 20.5" "Cell line enhanced" "Detected in many" "EFO-21: 219.9;HUVEC TERT2: 349.6;SK-MEL-30: 221.8;TIME: 201.1;U-87 MG: 187.1" "Low region specificity" "Detected in all" HPA045255 Uncertain NA NA 3400000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "HPA045255: AB_10794781" "unprognostic (1.30e-1)" "unprognostic (8.04e-2)" "unprognostic (2.53e-1)" "unprognostic (4.89e-3)" "unprognostic (4.94e-2)" "unprognostic (2.63e-2)" "unprognostic (2.58e-2)" "unprognostic (3.58e-2)" "unprognostic (3.27e-2)" "unprognostic (1.88e-1)" "unprognostic (1.42e-1)" "unprognostic (2.62e-2)" "unprognostic (1.91e-2)" "unprognostic (2.14e-3)" "unprognostic (1.93e-1)" "unprognostic (2.94e-1)" "unprognostic (4.71e-3)" 75.5 16.8 14.4 8.1 14.6 2.5 64.4 14.7 22.0 24.9 13.7 23.5 6.7 26.8 10.9 10.9 33.5 15.5 48.3 14.1 14.7 34.9 12.1 39.8 7.8 14.9 14.6 56.7 8.8 4.4 9.3 85.9 15.3 15.8 6.4 1.5 9.1 17.9 15.4 11.4 16.1 16.7 15.1 39.0 16.0 3.3 16.1 19.0 29.1 18.6 3.5 27.9 18.4 14.9 0.2 34.2 67.2 31.0 51.2 40.0 0.0 34.8 67.7 19.0 26.7 0.1 2.9 0.0 219.9 17.5 79.9 0.5 0.5 3.2 23.8 0.2 2.0 11.0 35.9 0.0 81.8 0.0 0.1 13.4 0.1 61.0 6.0 78.7 349.6 0.0 0.1 0.2 85.9 0.0 0.1 0.1 5.8 0.0 10.4 32.5 7.6 0.1 41.3 0.0 0.1 67.2 0.0 0.2 221.8 8.6 144.4 2.4 201.1 93.4 10.4 68.3 3.9 0.0 0.2 0.7 187.1 0.0 81.8 20.5 0.7 0.3 0.1 0.1 0.2 2.3 0.0 0.0 1.0 2.0 0.2 0.0 9.8 0.0 0.1 3.7 0.1 50.2 14.4 14.6 14.7 22.0 14.1 14.7 14.9 14.6 15.3 15.1 16.1 14.9 1903.6 12.8 27.3 1.3 20.6 83.6 11.8 3.1 5.7 0.7 15.2 26.8 94.8 11.5 3.1 187.6 0.0 2.3 15.4 0.1 74.3 135.7 5.9 124.1 94.6 1236.2 0.0 40.6 0.0 5.7 12.9 207.3 0.5 236.4 2.5 12.7 994.2 11.1 17.0 0.0 0.0 0.3 18.3 55.9 89.5 17.0 82.3 481.1 188.5 26.2 49.6 9.2 41.2 0.5 0.2 4.3 0.0 86.9 8.0 11.0 0.0 12.9 1.7 4.7 151.2 115.5 165.0 1.9 7.6 2.7 65.8 23.8 15.9 109.9 0.0 4.5 GPR1 ENSG00000183671 "G protein-coupled receptor 1" P46091 2 206175316-206218047 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 12.2" "Group enriched" "Detected in some" 6 "Extravillous trophoblasts: 12.3;Granulosa cells: 42.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 2.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 24.7;HHSteC: 133.9;hTCEpi: 61.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA010525 Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "Nucleoplasm, Vesicles" "HPA010525: AB_1078919" "unprognostic (5.32e-2)" "unprognostic (1.20e-1)" "unprognostic (2.82e-1)" "unprognostic (2.25e-2)" "unprognostic (3.27e-5)" "unprognostic (1.36e-1)" "unprognostic (4.00e-3)" "unprognostic (1.49e-2)" "unprognostic (7.89e-2)" "unprognostic (9.94e-2)" "unprognostic (3.42e-3)" "unprognostic (5.65e-2)" "unprognostic (4.29e-4)" "unprognostic (8.48e-4)" "unprognostic (1.21e-1)" "unprognostic (2.68e-2)" "unprognostic (3.06e-3)" 1.5 2.7 0.1 0.2 0.9 0.0 0.7 0.5 0.3 2.6 12.2 0.3 0.1 0.5 0.2 4.5 0.5 1.2 1.6 0.6 0.3 0.4 0.0 0.2 0.8 0.0 0.0 1.3 0.0 0.4 0.2 3.9 0.0 0.2 0.3 0.7 0.9 0.1 0.7 4.8 0.3 1.0 0.0 0.0 0.1 0.9 0.2 0.0 0.3 2.4 0.3 1.0 5.6 0.0 2.2 0.2 1.8 0.0 0.4 7.5 0.6 14.4 24.7 8.8 7.4 0.0 0.0 0.0 0.8 7.3 0.6 0.2 0.7 0.0 2.9 0.0 0.3 0.0 4.2 0.0 133.9 0.0 0.0 5.5 61.8 12.5 20.0 10.2 0.0 0.0 0.0 0.0 17.8 0.0 0.0 0.0 6.9 0.5 1.3 0.0 0.0 0.0 0.0 0.0 0.3 6.1 2.9 0.0 0.0 1.6 0.1 0.0 0.3 10.5 4.8 12.5 1.1 0.0 0.0 0.0 3.8 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.5 0.3 0.6 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.5 0.6 0.6 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.8 0.0 12.3 4.5 0.0 0.0 0.0 42.1 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 3.3 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.9 1.2 0.0 0.0 0.8 1.0 0.7 0.5 0.0 0.0 0.4 GRAP ENSG00000154016 "GRB2 related adaptor protein" Q13588 17 19020656-19047011 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 37.5" "Cell type enhanced" "Detected in some" "Adipocytes: 11.2;B-cells: 21.2;Endothelial cells: 19.8;Hepatic stellate cells: 30.7;Microglial cells: 9.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 99.7;T-cells: 133.6" "Cell line enhanced" "Detected in some" "Daudi: 87.1;HUVEC TERT2: 38.9;JURKAT: 30.1;REH: 47.8;TIME: 70.4;U-698: 60.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046595, HPA066654" Uncertain Approved Centrosome NA NA 1400000 "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Centrosome "HPA046595: AB_10966385, HPA066654: AB_2685699" "unprognostic (3.02e-1)" "unprognostic (6.85e-2)" "unprognostic (6.25e-2)" "unprognostic (2.78e-2)" "unprognostic (3.43e-2)" "unprognostic (3.86e-6)" "unprognostic (1.01e-1)" "unprognostic (1.02e-1)" "unprognostic (4.03e-3)" "unprognostic (1.85e-1)" "unprognostic (4.38e-2)" "unprognostic (5.11e-2)" "unprognostic (2.67e-5)" "unprognostic (2.25e-1)" "unprognostic (1.57e-2)" "unprognostic (2.16e-1)" "unprognostic (5.77e-3)" 6.3 3.5 6.7 13.9 6.2 6.5 5.9 6.1 6.9 3.9 5.0 2.6 1.9 3.3 0.5 1.8 4.6 5.3 3.7 5.8 6.1 4.9 6.0 7.1 36.9 6.8 6.5 1.8 0.9 0.6 1.9 6.1 6.8 2.7 1.8 0.4 1.6 3.7 1.7 2.4 15.7 3.3 6.5 37.5 2.2 6.3 7.0 31.9 5.5 1.4 30.7 3.6 2.2 6.0 0.0 0.2 4.5 0.0 0.0 0.1 1.7 0.1 0.0 0.0 0.0 0.1 0.0 87.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 5.2 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 38.9 30.1 0.2 0.0 0.0 0.2 19.9 1.9 0.9 0.0 0.0 47.8 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.0 6.8 70.4 0.0 0.2 9.8 0.1 0.1 0.0 60.2 0.1 0.1 0.3 21.5 9.4 1.3 21.5 4.8 21.5 99.7 67.4 28.4 10.5 82.7 133.6 66.5 2.9 21.4 0.4 7.9 62.3 48.9 6.7 6.2 6.1 6.9 5.8 6.1 6.8 6.5 6.8 6.5 7.0 6.0 11.2 6.4 1.8 0.0 21.2 1.0 0.0 0.0 0.0 0.0 0.4 0.6 0.2 0.0 0.6 0.0 0.0 0.1 3.1 0.0 0.0 0.3 2.3 1.1 0.2 19.8 0.0 4.0 0.0 0.0 0.7 0.4 0.0 1.2 2.5 0.1 30.7 0.8 8.2 0.0 0.0 0.4 0.0 4.4 0.7 0.8 0.0 1.9 0.0 9.4 2.9 0.2 2.1 0.0 0.1 0.2 0.0 0.4 3.0 0.0 0.0 0.1 0.0 0.3 0.0 0.3 0.3 0.7 0.3 0.0 1.0 0.3 6.9 0.5 0.3 0.0 GRB7 ENSG00000141738 "Growth factor receptor bound protein 7" Q14451 17 39737927-39747291 "Cancer-related genes, Predicted intracellular proteins" "Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 60.2;kidney: 61.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 77.1;Basal squamous epithelial cells: 104.7;Prostatic glandular cells: 79.0;Squamous epithelial cells: 124.7;Syncytiotrophoblasts: 98.6;Urothelial cells: 79.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 11 "cerebellum: 5.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "OE19: 1706.0" "Region enhanced" "Detected in many" "cerebellum: 8.3" "Low region specificity" "Detected in many" "CAB005226, HPA057084, CAB073538" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "CAB005226: AB_2113278, CAB073538: , HPA057084: AB_2683330" "unprognostic (8.46e-2)" "unprognostic (2.06e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (6.60e-7)" "unprognostic (7.06e-3)" "unprognostic (2.09e-2)" "unprognostic (1.02e-1)" "unprognostic (1.85e-1)" "unprognostic (2.02e-1)" "prognostic unfavorable (3.10e-4)" "prognostic unfavorable (6.90e-4)" "unprognostic (2.59e-2)" "prognostic favorable (8.23e-5)" "unprognostic (1.83e-2)" "unprognostic (4.77e-2)" "unprognostic (5.49e-3)" "unprognostic (4.01e-2)" 5.9 0.1 0.0 0.7 0.4 0.0 14.2 5.6 0.4 13.5 4.5 8.1 11.8 3.3 3.8 60.2 22.3 9.5 1.2 0.2 0.0 61.5 11.1 10.6 0.1 0.0 0.4 1.0 32.7 11.4 6.9 11.9 0.5 14.5 10.0 0.1 25.2 11.6 0.3 39.9 10.8 1.0 0.0 0.5 16.9 1.2 0.1 1.1 6.6 0.1 8.7 7.5 26.2 0.3 12.6 14.4 0.0 0.0 0.0 0.0 19.1 0.0 0.8 0.1 0.5 44.7 24.3 0.0 4.2 0.4 0.9 24.1 0.0 16.1 0.0 0.0 2.1 0.0 6.4 38.5 0.0 0.0 0.0 0.0 15.1 0.2 3.7 2.5 0.1 0.0 0.0 0.0 0.0 11.5 0.2 0.1 4.9 1706.0 3.4 0.1 0.0 18.6 18.5 14.0 9.5 0.1 18.4 370.7 0.1 17.3 14.0 0.0 0.0 0.0 1.1 0.2 0.0 0.2 0.1 1.0 1.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.6 0.4 0.2 0.0 0.0 0.4 0.5 0.0 0.1 0.3 0.5 22.4 15.1 0.0 0.9 38.2 77.1 20.0 104.7 0.2 48.2 30.5 2.5 17.2 18.2 22.0 0.0 35.7 0.7 25.6 9.8 35.6 0.0 30.2 5.3 2.6 14.4 0.0 0.3 19.4 27.4 3.1 27.0 41.8 1.3 0.5 0.4 5.1 2.8 0.0 0.0 19.7 40.7 0.0 2.3 0.0 2.8 1.3 5.4 0.0 1.6 0.4 0.0 0.0 0.0 26.7 26.0 1.2 0.3 79.0 28.3 13.8 20.9 0.1 0.0 0.9 2.1 0.4 0.3 124.7 41.9 98.6 1.4 0.0 21.1 79.7 GTF2IRD1 "BEN, Cream1, GTF3, MusTRD1, RBAP2, WBSCR11, WBSCR12" ENSG00000006704 "GTF2I repeat domain containing 1" Q9UHL9 7 74453790-74602605 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 68.1" "Cell type enhanced" "Detected in many" "Astrocytes: 48.3;Inhibitory neurons: 42.1;Rod photoreceptor cells: 41.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044254 Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm Cytosol "HPA044254: AB_10964747" "unprognostic (8.92e-2)" "unprognostic (6.94e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.71e-5)" "unprognostic (2.24e-1)" "unprognostic (3.35e-2)" "unprognostic (2.71e-3)" "unprognostic (3.77e-2)" "unprognostic (1.84e-2)" "unprognostic (6.26e-2)" "unprognostic (4.89e-3)" "unprognostic (3.31e-1)" "unprognostic (2.53e-1)" "unprognostic (8.61e-2)" "unprognostic (1.08e-1)" "unprognostic (3.06e-2)" "unprognostic (2.25e-3)" 6.0 12.6 7.0 3.4 7.0 0.5 6.9 7.2 8.1 16.8 14.0 15.1 7.7 11.3 8.6 26.7 8.8 5.7 11.6 6.0 8.4 18.6 4.6 11.7 1.0 9.2 8.9 10.5 10.0 18.9 27.6 5.8 9.0 13.3 5.6 36.7 17.3 8.2 68.1 22.4 6.7 8.4 6.7 2.0 13.9 5.0 10.1 3.4 17.4 29.7 5.4 15.0 19.8 10.2 21.2 12.9 28.1 30.8 22.2 10.8 0.2 8.8 23.7 17.1 17.7 21.7 30.1 5.4 6.5 18.1 41.7 11.6 22.6 10.2 12.6 0.2 13.0 1.1 43.1 26.1 71.2 0.2 0.7 14.7 42.1 12.0 48.9 39.7 8.9 10.4 15.5 0.1 19.2 26.1 2.7 18.9 22.6 25.7 12.8 28.1 16.4 20.0 32.7 14.6 23.1 30.5 21.7 39.0 19.9 14.2 23.4 21.2 4.6 17.5 16.9 11.4 20.5 1.1 3.4 8.9 6.7 0.3 14.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 7.0 7.0 7.2 8.1 6.0 8.4 9.2 8.9 9.0 6.7 10.1 10.2 0.9 9.6 8.2 48.3 0.1 7.9 9.9 10.5 9.6 30.8 5.6 4.1 10.4 12.8 6.8 9.2 33.3 1.4 1.5 4.5 11.7 7.6 1.6 11.5 8.0 4.1 4.2 0.8 24.6 9.2 1.8 5.6 6.1 17.0 2.5 8.0 2.9 3.1 2.6 21.9 42.1 3.6 8.2 1.2 5.7 0.3 4.1 2.5 7.2 14.0 0.7 5.9 1.0 25.6 24.9 11.6 3.2 5.7 0.0 17.8 3.6 17.4 12.7 41.1 0.0 19.0 5.7 0.1 3.7 18.2 6.7 2.9 1.1 2.4 7.4 15.8 HDAC7 "DKFZP586J0917, HDAC7A" ENSG00000061273 "Histone deacetylase 7" Q8WUI4 12 47782722-47833132 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 101.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 6.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 6.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004775 Supported Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA004775: AB_1850548" "unprognostic (3.83e-1)" "unprognostic (9.49e-3)" "unprognostic (1.37e-2)" "unprognostic (4.46e-2)" "unprognostic (6.56e-3)" "unprognostic (2.22e-2)" "unprognostic (2.50e-3)" "unprognostic (1.26e-1)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.28e-1)" "unprognostic (2.07e-1)" "unprognostic (2.38e-2)" "prognostic unfavorable (8.25e-4)" "unprognostic (6.24e-2)" "unprognostic (4.38e-2)" "unprognostic (9.69e-2)" "prognostic favorable (4.65e-4)" 52.5 41.8 7.7 28.5 8.1 23.6 45.3 3.2 9.7 46.2 24.6 44.2 8.9 51.4 13.6 23.5 50.3 16.8 31.6 4.1 4.8 29.3 6.0 55.0 27.3 17.2 7.1 44.9 14.5 20.1 20.6 19.5 10.2 34.4 4.8 2.8 30.6 17.1 16.2 40.1 28.6 16.9 3.4 38.4 27.2 7.9 10.7 80.0 39.2 9.4 15.2 44.3 38.5 7.6 41.6 28.1 28.6 46.9 21.9 60.2 25.3 39.4 30.7 28.3 18.8 37.4 38.4 80.5 126.8 37.1 13.9 37.8 6.7 31.4 10.5 38.8 13.6 27.6 29.9 8.6 23.6 9.1 1.2 39.4 10.8 28.6 15.4 51.6 58.6 45.9 29.9 33.4 18.6 18.0 83.2 21.8 39.4 9.1 29.1 64.2 14.7 29.6 12.1 26.9 8.1 18.8 30.6 14.1 14.4 18.4 13.4 12.0 66.6 56.9 61.0 47.6 28.9 70.8 58.8 67.4 23.8 41.9 19.1 0.0 1.4 0.0 0.8 0.5 0.9 0.8 0.7 0.7 0.4 0.5 0.8 0.6 6.5 0.9 0.5 0.3 0.3 1.5 7.7 8.1 3.2 9.7 4.1 4.8 17.2 7.1 10.2 3.4 10.7 7.6 80.6 41.7 32.1 34.9 32.7 13.8 26.8 28.7 8.6 20.3 22.5 17.4 13.4 28.6 28.6 36.8 0.0 4.8 18.6 5.3 1.9 31.6 15.5 26.2 39.4 79.3 7.3 40.4 19.9 23.0 3.5 37.8 25.5 58.4 8.8 20.2 101.7 2.0 15.6 28.6 17.5 9.6 24.4 32.7 14.1 6.9 55.0 13.3 14.2 46.9 20.5 11.7 28.8 10.6 13.6 66.8 7.3 33.1 42.9 69.1 0.6 3.8 31.8 4.0 26.3 18.3 26.9 1.1 3.7 10.3 21.6 2.9 28.2 9.3 8.1 46.8 HFM1 "FLJ36760, FLJ39011, MER3, SEC63D1" ENSG00000162669 "Helicase for meiosis 1" A2PYH4 1 91260766-91404856 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Meiosis "Helicase, Hydrolase" "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pituitary gland: 9.3;testis: 13.8" "Cell type enhanced" "Detected in some" "Astrocytes: 50.9;Inhibitory neurons: 38.4;Oligodendrocyte precursor cells: 90.5;Spermatocytes: 58.9" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 5.2;AN3-CA: 2.8;K-562: 3.0;SH-SY5Y: 2.1;U-266/70: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035036, HPA035557" Supported "Golgi apparatus,Vesicles" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Golgi apparatus, Vesicles" "HPA035036: AB_2797224, HPA035557: AB_10696507" "unprognostic (1.35e-2)" "unprognostic (9.39e-2)" "unprognostic (1.17e-1)" "unprognostic (2.83e-4)" "unprognostic (2.05e-2)" "unprognostic (1.52e-1)" "unprognostic (7.43e-3)" "unprognostic (1.79e-1)" "unprognostic (7.75e-2)" "unprognostic (7.97e-2)" "unprognostic (1.76e-4)" "unprognostic (2.81e-2)" "unprognostic (1.06e-2)" "unprognostic (2.89e-3)" "unprognostic (2.78e-2)" "unprognostic (1.77e-4)" "unprognostic (9.59e-2)" 0.4 0.3 1.0 0.1 1.0 0.2 0.4 5.1 1.0 0.9 0.0 0.5 0.3 2.3 1.1 0.1 0.8 0.2 0.6 0.7 1.6 0.7 0.1 0.2 0.1 1.7 1.6 3.9 0.7 0.1 9.3 0.5 1.1 0.6 0.3 4.5 0.5 1.1 1.5 0.1 0.2 0.9 1.1 0.4 0.2 13.8 1.6 0.1 1.6 1.1 0.2 0.4 0.3 1.3 0.0 0.1 5.2 2.8 0.0 0.1 0.0 0.3 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.1 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.0 0.0 0.3 0.1 1.6 0.0 0.0 0.2 1.0 0.0 0.0 0.0 1.7 2.1 0.0 0.0 0.7 1.4 0.0 0.5 0.0 0.0 0.5 0.5 0.1 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 5.1 1.0 0.7 1.6 1.7 1.6 1.1 1.1 1.6 1.3 0.2 0.0 1.1 50.9 0.0 0.0 0.0 0.0 0.6 3.9 0.1 0.3 3.1 0.0 0.0 0.0 6.2 0.5 0.0 0.0 0.0 0.4 17.8 0.2 1.9 0.4 0.0 2.5 17.6 0.2 0.2 0.6 0.0 0.0 0.0 5.9 0.0 0.0 0.1 0.0 38.4 0.0 0.0 0.0 0.0 5.0 4.1 0.0 0.0 10.3 0.0 2.4 0.0 90.5 9.5 0.1 0.0 2.2 0.0 0.1 0.0 0.0 0.0 6.2 0.0 2.0 1.4 58.9 15.6 0.0 0.0 0.0 0.0 1.8 0.0 0.0 HID1 "C17orf28, DMC1, HID-1" ENSG00000167861 "HID1 domain containing" Q8IV36 17 74950742-74973166 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 111.2" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 71.4;Intestinal goblet cells: 89.5;Paneth cells: 87.8;Proximal enterocytes: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 115.9;OE19: 99.2;SH-SY5Y: 56.7;SK-BR-3: 172.6;T-47d: 101.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031406 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus, Cytosol" "HPA031406: AB_2673866" "unprognostic (7.41e-2)" "unprognostic (1.96e-1)" "unprognostic (2.69e-1)" "unprognostic (2.22e-3)" "unprognostic (4.47e-3)" "unprognostic (6.79e-3)" "unprognostic (4.00e-2)" "unprognostic (1.11e-1)" "unprognostic (2.78e-1)" "unprognostic (3.90e-1)" "unprognostic (1.54e-3)" "unprognostic (1.37e-1)" "prognostic favorable (3.13e-5)" "unprognostic (1.17e-1)" "unprognostic (2.83e-1)" "unprognostic (1.09e-1)" "prognostic favorable (1.34e-4)" 13.2 5.8 21.7 6.6 26.9 2.0 23.2 41.5 33.3 19.9 2.8 17.9 39.1 11.9 29.1 5.5 19.0 21.6 12.4 22.0 24.3 12.3 4.4 20.4 5.3 27.4 22.7 3.0 111.2 14.4 44.0 20.1 30.3 36.2 17.9 8.7 86.2 20.2 4.6 7.6 27.3 6.3 10.4 16.7 68.7 6.8 25.4 2.8 16.8 5.7 6.3 12.3 7.6 39.1 5.2 11.4 1.3 15.8 0.0 0.0 2.7 0.0 0.6 1.1 1.0 10.6 5.8 0.0 1.0 0.0 1.4 4.9 14.5 1.0 0.8 0.0 11.4 0.1 0.3 10.1 2.7 0.0 1.1 0.2 6.0 0.1 2.4 0.3 26.0 3.8 0.7 4.0 0.0 115.9 0.7 0.2 0.4 99.2 7.1 0.2 0.0 21.8 14.5 44.8 21.1 56.7 0.0 172.6 0.0 3.6 101.2 0.0 0.5 0.1 1.4 0.4 0.0 2.0 0.3 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.5 0.6 0.9 0.7 0.0 0.1 1.0 1.1 0.0 0.0 0.0 2.6 0.0 0.4 21.7 26.9 41.5 33.3 22.0 24.3 27.4 22.7 30.3 10.4 25.4 39.1 21.4 0.0 5.5 4.9 4.6 1.5 2.6 3.1 0.6 14.3 20.4 12.3 3.8 4.3 8.6 0.0 0.0 26.3 1.1 16.0 3.9 19.0 0.4 10.2 3.0 19.1 35.3 0.0 16.1 26.9 1.7 1.0 71.4 20.3 0.0 1.1 20.7 0.4 2.5 20.2 15.5 89.5 16.2 0.8 0.4 1.0 0.9 0.7 7.2 6.5 0.6 2.8 0.0 8.0 50.9 22.9 87.8 0.0 22.7 17.8 107.4 0.5 6.5 4.4 0.0 1.5 1.8 0.4 2.1 0.5 0.4 35.0 1.8 0.1 15.6 13.9 HIVEP3 "FLJ16752, KBP-1, KBP1, KIAA1555, KRC, Schnurri-3, SHN3, ZAS3, ZNF40C" ENSG00000127124 "HIVEP zinc finger 3" Q5T1R4 1 41506365-42035925 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 6.6" "Group enriched" "Detected in many" 5 "Astrocytes: 83.9;Excitatory neurons: 219.6;Inhibitory neurons: 271.9;Microglial cells: 163.9;Oligodendrocyte precursor cells: 83.9;Oligodendrocytes: 196.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HDLM-2: 18.8;hTEC/SVTERT24-B: 9.5;Karpas-707: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005728 Approved Supported Nucleoplasm NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA005728: AB_10612117" "unprognostic (2.87e-3)" "unprognostic (2.38e-2)" "unprognostic (4.65e-2)" "unprognostic (2.56e-1)" "unprognostic (1.55e-2)" "unprognostic (6.50e-2)" "unprognostic (2.70e-3)" "unprognostic (3.73e-1)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "unprognostic (1.19e-1)" "unprognostic (2.41e-1)" "unprognostic (2.07e-8)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "unprognostic (1.13e-2)" "unprognostic (3.21e-1)" 1.6 0.6 0.8 2.1 2.1 1.6 1.4 1.4 1.6 0.4 0.0 0.5 0.4 0.4 0.3 1.9 0.5 0.7 0.8 2.0 0.0 1.0 0.3 1.9 1.7 0.7 0.4 0.5 0.8 0.4 2.1 0.6 1.0 1.4 0.5 0.6 1.6 0.3 0.6 4.6 0.6 0.8 0.1 1.1 0.7 0.3 0.5 6.6 1.5 0.4 2.1 1.8 0.5 0.3 1.9 0.6 0.2 1.8 2.2 1.0 0.0 0.9 0.2 2.3 4.0 0.1 0.3 4.0 0.6 1.0 1.5 2.7 0.4 0.4 3.1 18.8 0.5 0.2 0.9 0.0 0.4 0.3 0.3 5.6 0.4 9.5 1.1 0.6 0.5 1.3 0.0 11.0 1.8 1.2 3.0 0.8 0.6 0.6 2.3 2.0 2.9 2.2 1.5 0.4 2.0 0.6 2.6 0.7 0.5 1.1 0.9 3.4 3.4 2.0 2.2 0.6 4.6 3.3 1.4 2.6 8.1 0.2 7.5 0.0 0.5 0.0 0.6 1.1 0.1 0.1 0.2 0.3 0.4 0.4 0.0 0.2 0.0 0.0 1.0 0.1 0.1 0.4 0.8 2.1 1.4 1.6 2.0 0.0 0.7 0.4 1.0 0.1 0.5 0.3 5.9 6.4 10.5 83.9 9.6 23.7 26.5 4.3 17.6 16.4 15.1 11.0 6.9 5.7 8.2 1.8 2.1 0.4 17.6 3.5 1.9 3.1 9.9 1.2 7.7 7.5 3.6 4.4 219.6 2.7 4.4 11.1 1.5 2.8 1.3 0.2 11.4 2.5 6.2 25.2 271.9 1.2 2.0 6.5 17.3 31.9 8.7 15.0 5.4 163.9 9.1 16.0 27.8 83.9 196.0 3.1 0.1 4.1 3.3 15.5 1.9 3.2 1.1 3.5 6.6 23.9 7.4 11.3 8.6 23.7 8.7 0.8 14.5 10.0 0.9 11.1 ICAM2 CD102 ENSG00000108622 "Intercellular adhesion molecule 2" P13598 17 64002594-64020634 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 168.1" "Cell type enhanced" "Detected in many" "Adipocytes: 341.8;Endothelial cells: 180.8;Hepatic stellate cells: 128.5;NK-cells: 106.1;Plasma cells: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "HUVEC TERT2: 1260.8;TIME: 319.0" "Low region specificity" "Detected in all" HPA071155 Approved "Plasma membrane,Cytosol" NA NA 730000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA071155: " "unprognostic (9.43e-3)" "unprognostic (3.31e-2)" "unprognostic (5.15e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (1.64e-3)" "unprognostic (1.34e-1)" "unprognostic (3.74e-1)" "unprognostic (8.28e-2)" "unprognostic (2.15e-1)" "unprognostic (4.18e-2)" "unprognostic (1.55e-2)" "unprognostic (9.07e-2)" "unprognostic (1.48e-1)" "unprognostic (3.93e-2)" "unprognostic (6.04e-2)" "unprognostic (2.29e-1)" 97.4 11.3 39.6 30.4 39.6 20.7 78.7 40.3 48.3 20.3 34.6 26.3 14.1 24.4 6.7 12.1 22.2 18.8 99.7 38.2 40.5 44.3 14.6 84.5 60.5 42.1 40.9 12.7 15.4 9.0 12.4 79.3 42.9 16.1 18.2 1.2 16.0 8.6 37.9 16.3 34.2 29.5 41.4 168.1 18.8 3.5 44.6 31.5 33.6 55.9 41.8 33.0 21.4 40.6 0.0 0.0 0.0 0.0 11.3 10.8 3.2 1.1 0.7 0.3 1.1 2.7 52.2 92.9 16.6 0.0 0.3 0.4 1.2 0.0 1.7 22.3 0.0 82.9 4.4 10.0 1.8 14.2 0.3 0.4 0.0 0.8 0.2 0.0 1260.8 78.8 67.7 50.5 0.3 0.0 101.8 11.8 0.1 0.7 0.0 60.3 0.2 128.7 6.7 12.8 0.0 0.8 0.0 0.2 0.0 0.1 0.0 10.3 319.0 0.2 0.8 6.2 0.0 47.6 18.7 83.4 0.1 17.7 0.0 444.8 191.8 62.1 282.8 464.6 326.0 265.6 371.2 270.7 203.6 328.9 400.3 253.3 23.1 188.5 525.8 67.2 450.8 502.0 39.6 39.6 40.3 48.3 38.2 40.5 42.1 40.9 42.9 41.4 44.6 40.6 341.8 0.0 8.4 0.0 47.8 7.4 4.0 5.2 0.6 0.1 6.1 11.3 0.5 1.5 4.5 7.3 0.0 0.5 41.7 1.7 0.0 1.2 0.6 1.2 2.4 180.8 1.2 28.2 0.1 1.4 0.3 13.8 1.1 0.8 12.0 0.7 128.5 1.9 20.0 0.0 0.0 2.2 2.0 55.6 13.4 1.3 0.3 56.9 28.4 21.5 25.7 0.4 106.1 0.5 0.2 6.8 4.7 1.9 114.4 3.8 0.6 0.5 4.1 0.5 6.6 7.4 11.6 0.2 0.3 0.7 5.4 1.0 60.1 6.5 4.2 2.8 IFI16 "IFNGIP1, PYHIN2" ENSG00000163565 "Interferon gamma inducible protein 16" Q16666 1 158999968-159055155 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Autophagy, Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 378.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002134, CAB016293, HPA073514" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nucleoli" Cytosol "CAB016293: AB_627775, HPA002134: AB_1079099, HPA073514: " "unprognostic (7.23e-3)" "unprognostic (2.20e-2)" "unprognostic (5.15e-2)" "unprognostic (7.70e-3)" "unprognostic (1.87e-1)" "unprognostic (6.08e-2)" "unprognostic (1.80e-1)" "unprognostic (5.83e-2)" "unprognostic (5.04e-2)" "unprognostic (2.26e-2)" "unprognostic (5.92e-3)" "unprognostic (7.62e-2)" "prognostic unfavorable (1.11e-16)" "unprognostic (5.07e-2)" "unprognostic (4.08e-1)" "unprognostic (7.97e-2)" "unprognostic (1.14e-1)" 95.7 37.9 13.5 114.5 17.5 35.5 72.8 14.3 14.1 56.8 9.1 38.3 23.8 76.5 22.7 63.6 54.2 100.6 35.0 13.7 20.3 30.1 27.7 68.2 140.6 29.9 22.7 76.8 16.7 9.7 9.3 66.7 27.0 26.5 45.0 7.7 63.7 32.0 16.8 58.8 47.9 87.3 23.6 107.8 30.7 18.8 23.8 116.8 37.4 32.6 133.1 113.6 52.8 26.2 43.5 3.2 14.4 0.6 97.4 319.5 0.4 89.9 238.0 245.7 324.2 0.0 54.1 251.7 75.4 55.3 79.2 122.2 2.2 91.1 97.7 78.4 1.1 64.9 17.2 0.1 181.8 22.8 4.2 302.4 159.5 126.5 177.8 117.8 262.8 218.1 1.4 179.4 138.6 0.0 302.2 21.1 38.4 0.0 32.5 140.6 91.4 295.0 34.4 16.1 6.6 0.1 117.7 1.0 259.5 56.9 0.4 26.3 150.2 63.1 29.7 179.9 38.2 165.8 82.8 235.5 181.2 72.7 155.7 9.1 67.7 0.4 57.5 66.4 51.9 88.4 54.3 59.4 68.3 94.6 33.9 43.3 164.4 91.6 65.3 51.1 82.1 63.8 13.5 17.5 14.3 14.1 13.7 20.3 29.9 22.7 27.0 23.6 23.8 26.2 378.4 38.5 54.6 4.2 217.8 95.0 110.7 197.6 174.8 0.4 47.8 43.8 10.7 37.1 130.7 42.3 0.0 3.4 278.3 7.9 1.9 38.0 4.9 41.9 219.1 286.8 12.1 38.7 1.3 47.8 2.9 207.8 9.7 68.0 138.3 27.7 137.4 3.0 214.2 0.0 2.2 19.9 79.3 163.8 135.0 9.8 117.4 187.2 83.6 116.2 202.4 30.8 329.6 37.2 20.7 47.1 23.5 53.0 143.3 32.6 7.9 4.9 76.6 1.4 85.5 185.3 132.7 2.4 13.2 92.6 68.2 3.3 219.2 70.6 26.4 107.5 IFI27 "FAM14D, ISG12, P27" ENSG00000165949 "Interferon alpha inducible protein 27" P40305 14 94104836-94116698 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense, Apoptosis, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 3792.9;Distal enterocytes: 2150.5;Endothelial cells: 1972.1;Exocrine glandular cells: 1603.8;Intestinal goblet cells: 1638.8;Pancreatic endocrine cells: 1678.1;Paneth cells: 2179.2;Proximal enterocytes: 3048.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 7.0" "Group enriched" "Detected in many" 6 "monocytes: 7.0;T-cells: 2.6" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 2026.8;BJ hTERT+ SV40 Large T+ RasG12V: 1782.5;EFO-21: 547.7;Karpas-707: 501.5;SK-MEL-30: 607.2" HPA028875 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA028875: AB_10601434" "unprognostic (1.15e-1)" "unprognostic (1.19e-1)" "unprognostic (2.43e-2)" "unprognostic (6.68e-2)" "unprognostic (4.74e-2)" "unprognostic (1.59e-2)" "unprognostic (6.78e-3)" "unprognostic (5.26e-2)" "unprognostic (2.10e-1)" "prognostic favorable (8.80e-4)" "unprognostic (1.13e-3)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.53e-1)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" "unprognostic (1.65e-1)" 470.3 323.3 178.3 115.7 177.4 162.8 410.3 180.9 232.6 351.4 162.7 374.4 129.2 137.8 39.9 310.4 163.2 344.1 471.5 174.5 182.4 217.9 150.4 608.2 48.3 203.8 187.7 75.6 39.3 30.3 65.3 183.8 215.0 85.0 221.4 6.1 156.9 47.0 113.1 129.8 256.2 117.4 194.9 797.8 697.0 140.2 194.1 202.8 149.8 152.4 54.2 116.9 213.7 190.8 181.3 0.4 1.3 0.4 0.5 21.7 1.7 2.8 8.8 2026.8 1782.5 3.8 146.8 1.5 547.7 115.3 33.8 5.7 1.1 0.2 79.7 2.1 3.7 1.0 1.4 0.9 13.7 0.6 1.1 2.0 2.0 353.8 0.1 1.1 284.0 1.3 1.1 501.5 0.1 0.5 1.7 1.1 0.5 0.5 24.7 1.8 0.5 0.6 1.2 0.6 0.4 1.1 0.0 0.1 607.2 1.4 0.9 3.0 0.3 0.2 2.7 325.8 1.0 9.4 14.6 3.9 0.9 0.5 1.4 0.0 1.3 0.5 0.3 7.0 0.3 0.0 2.6 0.7 0.8 0.1 0.0 0.4 0.0 0.4 2.1 0.1 2.5 2.1 178.3 177.4 180.9 232.6 174.5 182.4 203.8 187.7 215.0 194.9 194.1 190.8 3792.9 391.0 82.7 1.3 26.8 171.2 6.5 126.9 91.6 4.9 23.4 38.2 45.9 151.5 237.4 12.9 8.4 7.3 14.9 2150.5 1.9 50.6 13.6 1035.5 188.3 1972.1 267.8 42.3 0.6 1603.8 221.2 330.8 892.5 838.5 45.1 1174.4 742.5 5.8 158.3 5.0 0.4 1638.8 107.8 106.9 163.5 36.7 172.1 59.6 350.4 84.3 26.1 8.3 0.0 0.0 0.7 1678.1 2179.2 417.5 6.3 11.1 3048.1 23.7 548.1 20.5 276.1 45.2 295.8 20.3 12.1 151.9 140.4 5.2 34.1 302.4 523.4 80.4 IL15RA "CD215, IL-15RA" ENSG00000134470 "Interleukin 15 receptor subunit alpha" Q13261 10 5943639-5978187 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 39.1;Exocrine glandular cells: 55.2;Fibroblasts: 37.6;Hepatic stellate cells: 36.0;monocytes: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 70.8;EFO-21: 41.3;HDLM-2: 78.5;HHSteC: 42.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in single" 8 "cerebellum: 7.1" CAB026215 Approved "Secreted to blood" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 50: Fibroblasts - ECM organization" "CAB026215: " "unprognostic (2.86e-2)" "unprognostic (8.41e-2)" "unprognostic (6.13e-2)" "unprognostic (4.45e-2)" "unprognostic (7.87e-2)" "unprognostic (5.49e-2)" "prognostic unfavorable (2.67e-6)" "unprognostic (5.09e-3)" "unprognostic (1.82e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.35e-4)" "unprognostic (6.18e-3)" "prognostic unfavorable (1.27e-12)" "unprognostic (4.43e-2)" "unprognostic (4.69e-2)" "unprognostic (4.08e-2)" "unprognostic (5.75e-2)" 19.3 7.5 3.3 20.4 3.7 11.7 18.3 3.0 4.6 21.5 3.6 12.3 16.2 15.0 4.6 11.5 18.8 23.2 17.8 2.8 4.4 14.1 19.5 44.5 21.3 5.7 3.9 3.7 11.5 2.2 4.6 16.1 4.6 10.4 10.9 0.3 8.0 5.3 7.1 11.2 15.7 12.1 4.8 15.1 16.3 3.2 4.6 5.7 12.1 10.2 11.6 25.7 12.7 3.5 16.8 2.4 0.0 0.7 21.5 4.9 4.3 8.6 18.4 10.7 11.4 0.3 70.8 1.9 41.3 16.0 6.0 15.6 2.0 12.1 2.4 78.5 3.5 2.0 4.9 1.2 42.7 0.9 0.6 4.1 4.2 6.0 0.2 4.4 29.1 1.3 20.5 23.5 0.3 9.3 3.6 8.9 0.4 6.7 6.8 10.0 0.0 13.4 2.8 1.3 0.1 0.1 12.9 1.4 0.6 0.2 6.1 8.0 10.8 0.5 1.3 30.1 11.2 20.5 6.2 0.4 4.9 12.4 0.7 10.2 26.0 6.6 18.9 32.8 29.1 10.8 14.7 19.7 7.1 6.4 6.1 11.0 7.5 11.5 21.0 0.1 17.7 12.8 3.3 3.7 3.0 4.6 2.8 4.4 5.7 3.9 4.6 4.8 4.6 3.5 25.2 6.4 5.0 1.3 6.0 5.7 5.7 9.9 4.6 0.0 4.4 3.0 5.8 22.8 3.3 0.0 0.0 0.6 4.2 5.8 0.0 39.1 1.7 5.1 23.0 21.0 5.4 19.8 3.3 55.2 1.6 37.6 9.7 6.7 3.8 0.1 36.0 8.7 6.6 0.0 0.9 6.8 2.0 14.7 5.5 2.1 5.0 7.3 3.6 12.2 55.0 0.0 4.1 1.0 0.3 35.5 13.3 0.7 22.2 20.1 9.3 0.1 3.4 0.0 0.0 7.1 6.4 0.2 0.4 4.6 6.5 0.1 7.8 0.0 9.3 6.8 IL1R1 "CD121A, D2S1473, IL1R, IL1RA" ENSG00000115594 "Interleukin 1 receptor type 1" P14778 2 102064544-102179874 "Cancer-related genes, CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Hydrolase, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 127.1;Endometrial stromal cells: 280.2;Glandular and luminal cells: 315.4;Hepatic stellate cells: 146.7;Langerhans cells: 188.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 624.9;ASC TERT1: 276.8;HHSteC: 196.3;HSkMC: 770.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001237, HPA005823, CAB007779, HPA029560" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1400000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Vesicles" "Plasma membrane, Cytosol" "CAB007779: AB_562073, HPA001237: , HPA005823: AB_2667445, HPA029560: AB_2673094" "unprognostic (6.16e-3)" "unprognostic (3.55e-2)" "unprognostic (3.33e-1)" "unprognostic (1.22e-1)" "unprognostic (4.26e-2)" "unprognostic (7.10e-2)" "unprognostic (2.01e-1)" "unprognostic (3.36e-2)" "unprognostic (1.44e-1)" "unprognostic (3.16e-1)" "unprognostic (4.26e-2)" "unprognostic (7.77e-2)" "prognostic unfavorable (6.92e-6)" "unprognostic (2.48e-2)" "unprognostic (6.95e-2)" "unprognostic (4.83e-2)" "unprognostic (7.73e-2)" 137.3 68.0 7.1 69.5 8.3 18.0 77.5 7.5 11.0 161.1 16.2 39.3 20.7 33.5 105.2 32.1 52.0 92.0 58.3 7.6 9.0 45.7 75.5 115.5 17.1 16.2 8.4 31.1 43.3 126.7 13.1 120.8 8.9 66.7 30.5 8.5 34.2 47.4 18.6 40.1 40.3 49.9 10.0 41.0 43.9 20.6 14.9 21.7 52.5 16.0 19.7 87.4 40.2 7.7 2.0 12.8 0.3 10.8 624.9 276.8 4.4 27.4 123.8 19.2 28.7 5.7 3.4 0.0 19.8 55.0 33.9 5.5 0.2 2.2 16.1 55.5 0.1 0.7 2.9 31.3 196.3 0.1 0.3 770.6 2.3 21.7 5.2 8.4 8.7 0.0 3.5 1.1 28.1 5.6 0.0 1.2 0.7 5.6 0.9 0.3 2.0 0.4 18.3 13.4 0.1 0.3 12.5 7.7 0.0 3.6 11.1 0.8 0.3 54.7 3.6 92.1 2.2 0.1 0.0 0.1 21.3 0.6 3.6 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.6 0.0 7.1 8.3 7.5 11.0 7.6 9.0 16.2 8.4 8.9 10.0 14.9 7.7 99.3 25.6 73.2 1.3 1.8 31.1 46.8 8.2 5.2 0.1 19.4 13.7 5.2 28.6 68.6 5.5 0.0 6.1 2.5 0.7 3.9 31.7 7.0 127.1 280.2 103.6 1.2 14.3 0.5 21.8 82.8 79.1 2.0 315.4 1.3 0.3 146.7 47.1 5.4 0.0 3.0 0.5 10.2 12.0 188.2 12.6 28.0 26.0 19.6 23.4 7.0 9.0 0.0 0.5 0.5 12.0 0.3 1.5 1.8 65.9 0.0 8.3 28.6 1.0 6.6 37.7 34.3 1.3 1.2 4.5 38.6 23.9 8.5 4.0 0.8 23.6 IL4R CD124 ENSG00000077238 "Interleukin 4 receptor" P24394 16 27313668-27364778 "Cancer-related genes, CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Immunity Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 92.0;granulocytes: 110.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 78.1" "Group enriched" "Detected in all" 5 "B-cells: 78.1;granulocytes: 31.1" "Cell line enhanced" "Detected in many" "Daudi: 124.2;HBEC3-KT: 115.0;HDLM-2: 110.6;U-698: 119.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004451, HPA050124, HPA070380" Enhanced Approved "Nucleoplasm,Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 38500 110000 "Cluster 37: B-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Plasma membrane" "Centriolar satellite" "CAB004451: AB_626889, HPA050124: AB_2681026, HPA070380: " "unprognostic (6.80e-2)" "unprognostic (6.35e-2)" "unprognostic (2.84e-1)" "prognostic favorable (6.43e-4)" "unprognostic (1.12e-1)" "unprognostic (1.14e-1)" "unprognostic (2.33e-2)" "unprognostic (1.95e-3)" "unprognostic (1.34e-1)" "unprognostic (1.54e-1)" "unprognostic (2.41e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.49e-2)" "unprognostic (1.73e-1)" "unprognostic (1.36e-1)" "unprognostic (9.58e-2)" 49.4 45.2 22.7 82.3 19.7 103.4 34.1 19.2 22.0 39.7 21.4 97.0 27.3 35.8 5.9 70.8 42.3 41.2 34.2 18.7 21.0 50.8 116.0 119.2 117.1 29.4 22.2 14.3 29.8 31.7 14.9 39.3 24.0 49.9 35.6 2.4 20.5 25.6 9.3 24.4 55.7 37.3 25.5 90.0 55.0 15.5 25.3 22.3 24.2 6.6 89.6 63.2 45.4 23.8 39.9 10.1 6.4 13.1 3.1 14.1 14.3 24.7 27.3 9.3 7.7 20.4 105.2 124.2 30.1 38.5 18.3 39.7 7.3 115.0 8.2 110.6 4.0 22.6 6.6 31.6 40.8 6.1 61.7 23.5 45.0 44.2 26.5 48.7 50.7 6.8 10.5 9.8 15.0 17.3 0.7 18.8 8.0 34.2 9.1 0.4 47.5 10.2 42.9 43.2 1.9 0.6 3.7 24.7 5.0 15.6 8.2 23.5 81.0 21.0 9.8 19.0 17.6 6.1 2.1 119.7 2.1 21.1 0.3 1.4 7.2 13.0 4.2 3.1 3.4 25.8 6.9 4.4 4.1 78.1 10.0 5.0 31.1 8.2 1.8 4.8 5.3 5.8 22.7 19.7 19.2 22.0 18.7 21.0 29.4 22.2 24.0 25.5 25.3 23.8 30.5 28.9 49.2 0.7 92.0 13.3 43.3 34.9 26.2 0.3 9.4 14.2 2.4 34.3 33.4 1.8 0.0 17.6 29.8 60.0 0.0 39.5 0.3 6.6 2.2 39.0 23.4 5.2 1.7 32.3 3.8 17.2 32.1 17.2 110.8 0.7 62.8 45.9 27.2 0.0 0.6 35.5 8.2 30.6 29.9 0.8 0.3 34.3 14.2 38.4 39.3 0.0 7.2 0.5 0.7 49.3 28.7 0.0 13.4 37.7 24.0 1.2 28.5 0.2 39.5 16.4 20.0 0.8 3.3 23.8 14.9 24.9 38.3 0.2 16.7 46.9 IRX3 IRX-1 ENSG00000177508 "Iroquois homeobox 3" P78415 16 54283304-54286787 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 89.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 66.7;Breast glandular cells: 133.8;Breast myoepithelial cells: 84.6;Endometrial ciliated cells: 73.0;Glandular and luminal cells: 88.2;Respiratory ciliated cells: 67.3;Squamous epithelial cells: 72.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 119.4;NB-4: 204.4;RPTEC TERT1: 236.4;T-47d: 122.9;THP-1: 201.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA066576 Approved Nucleoplasm,Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 24: NB-4 - Immune response" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm Cytosol "HPA066576: " "unprognostic (4.21e-3)" "unprognostic (4.50e-2)" "unprognostic (2.34e-2)" "unprognostic (1.04e-1)" "unprognostic (3.34e-2)" "unprognostic (2.35e-1)" "unprognostic (1.39e-1)" "unprognostic (1.35e-2)" "unprognostic (1.52e-1)" "unprognostic (9.75e-2)" "unprognostic (2.92e-1)" "unprognostic (1.07e-1)" "unprognostic (3.15e-2)" "unprognostic (5.40e-2)" "unprognostic (2.39e-1)" "unprognostic (8.20e-2)" "unprognostic (1.25e-1)" 8.2 6.8 3.4 0.4 3.0 0.1 75.6 6.3 1.2 29.7 2.7 0.3 0.4 2.2 36.5 33.0 10.9 0.3 63.1 1.2 5.1 42.6 2.2 36.5 2.0 7.5 8.1 0.9 4.0 27.2 7.2 1.9 6.2 23.2 0.0 1.2 43.2 31.3 22.7 89.3 0.6 1.2 6.2 0.1 22.5 0.5 7.5 1.0 9.3 8.8 4.5 4.8 17.5 5.0 1.1 1.1 15.6 15.1 8.4 3.3 1.7 6.6 14.5 13.9 3.4 4.2 6.8 0.0 2.2 10.0 5.5 29.0 12.6 3.6 18.5 14.3 9.8 0.0 22.2 14.6 0.6 16.7 4.1 2.5 59.7 26.5 12.0 9.8 0.0 19.1 0.0 0.0 119.4 7.7 30.9 204.4 1.1 0.0 0.0 23.2 19.2 0.0 236.4 6.2 10.6 1.9 20.4 51.3 2.6 1.7 122.9 201.8 3.4 57.9 6.4 10.6 5.3 0.0 0.0 0.1 38.0 53.7 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 3.0 6.3 1.2 1.2 5.1 7.5 8.1 6.2 6.2 7.5 5.0 2.6 19.2 66.7 0.0 0.4 25.0 47.4 25.3 45.5 1.3 133.8 84.6 14.1 0.0 43.2 5.5 0.0 0.1 1.3 0.1 1.9 5.2 0.0 73.0 8.1 5.8 0.0 0.0 0.0 0.2 0.1 18.3 2.0 88.2 0.0 5.5 8.2 7.1 0.3 0.0 0.0 0.0 36.7 1.2 2.7 0.0 0.0 9.0 10.6 0.0 0.2 10.4 0.0 0.0 0.0 0.1 0.0 0.0 1.7 25.8 0.0 6.5 67.3 1.2 0.0 32.1 6.4 0.4 1.0 72.8 41.3 0.0 1.1 0.1 0.0 34.0 ITGA3 "CD49c, GAP-B3, MSK18, VCA-2, VLA3a" ENSG00000005884 "Integrin subunit alpha 3" P26006 17 50055968-50090481 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 111.9;Exocrine glandular cells: 105.1;Pancreatic endocrine cells: 245.6;Urothelial cells: 104.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 647.2;hTERT-RPE1: 572.8;RPTEC TERT1: 562.0;U-87 MG: 920.8;WM-115: 570.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008572, CAB018594" Enhanced Supported "Plasma membrane" NA NA 170000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" "CAB018594: AB_668044, HPA008572: AB_2668094" "unprognostic (3.24e-3)" "prognostic unfavorable (6.75e-4)" "unprognostic (9.51e-2)" "unprognostic (3.46e-3)" "unprognostic (3.45e-3)" "prognostic unfavorable (1.36e-4)" "unprognostic (8.28e-3)" "unprognostic (2.76e-3)" "unprognostic (1.26e-3)" "unprognostic (1.82e-2)" "prognostic unfavorable (5.95e-5)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (1.30e-1)" "unprognostic (1.28e-2)" "unprognostic (2.35e-2)" 17.5 29.8 5.3 9.9 5.4 0.4 17.3 6.0 6.1 14.8 5.2 25.4 30.4 21.3 11.7 24.1 24.5 17.9 13.2 5.0 10.9 68.9 2.2 65.8 3.0 7.5 6.6 12.8 15.9 17.7 21.1 26.7 11.9 19.5 15.5 4.4 19.4 15.7 9.0 30.8 26.7 15.6 4.2 11.1 24.5 2.1 7.8 5.9 43.5 4.1 6.2 46.7 17.1 4.0 181.8 234.9 1.4 7.5 4.3 17.5 37.3 83.4 177.9 123.1 93.2 5.3 276.2 0.4 507.9 59.5 400.4 126.8 2.2 647.2 73.9 22.9 3.5 0.1 56.8 1.6 105.1 0.3 5.0 21.6 313.5 123.2 540.7 572.8 91.6 9.1 0.1 2.6 236.0 52.9 0.7 0.5 5.5 81.2 141.0 0.4 12.1 13.7 562.0 311.1 9.7 3.9 89.8 12.2 205.0 56.2 21.1 2.4 200.8 541.8 169.4 5.6 329.5 8.1 14.2 5.9 920.8 1.9 570.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.3 5.4 6.0 6.1 5.0 10.9 7.5 6.6 11.9 4.2 7.8 4.0 8.5 54.5 30.1 3.6 3.4 57.4 63.5 63.5 48.3 18.0 17.1 32.0 5.3 27.1 26.2 77.3 25.0 2.8 1.3 91.2 0.0 111.9 0.5 26.4 3.1 14.7 14.5 0.0 24.3 105.1 3.2 5.3 47.4 20.7 3.8 3.4 8.9 0.3 1.1 3.3 20.0 25.1 16.2 1.2 8.2 0.6 1.8 2.0 17.8 8.4 4.3 3.1 2.1 3.0 0.8 245.6 26.7 4.1 4.5 72.6 69.6 4.4 21.7 16.2 13.1 5.6 23.4 0.5 1.6 17.0 23.2 1.8 3.8 0.9 44.7 104.2 KCNIP4 "CALP, KCHIP4, MGC44947" ENSG00000185774 "Potassium voltage-gated channel interacting protein 4" Q6PIL6 4 20728606-21948772 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.5;retina: 18.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 9816.7;Inhibitory neurons: 1982.4;Oligodendrocyte precursor cells: 5175.8" "Cancer enhanced" "Detected in some" "glioma: 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "RPTEC TERT1: 6.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022862, HPA066717" Supported Approved Vesicles NA NA "Cluster 58: Brain - Synaptic function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA022862: AB_1852654, HPA066717: " "unprognostic (8.08e-2)" "unprognostic (1.05e-1)" "unprognostic (7.36e-2)" "unprognostic (4.14e-2)" "unprognostic (9.26e-2)" "unprognostic (1.49e-1)" "unprognostic (2.53e-1)" "unprognostic (2.99e-2)" "unprognostic (1.18e-1)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (2.13e-1)" "unprognostic (3.11e-1)" "unprognostic (1.03e-2)" "unprognostic (2.69e-1)" "unprognostic (4.59e-2)" "unprognostic (2.10e-2)" 0.6 2.2 11.9 1.3 16.4 0.0 0.6 13.8 24.5 11.0 0.0 6.9 1.2 6.2 0.6 4.0 2.5 1.1 0.5 17.8 12.8 8.2 0.2 0.5 0.0 7.0 7.9 1.3 0.5 0.0 4.2 1.0 13.7 0.5 4.1 18.1 0.5 0.3 0.3 0.5 3.8 6.0 4.3 0.3 0.8 0.4 9.0 0.0 6.4 0.0 0.0 1.0 1.5 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.3 0.1 0.0 0.2 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.4 0.4 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 16.4 13.8 24.5 17.8 12.8 7.0 7.9 13.7 4.3 9.0 10.6 0.0 0.0 0.0 148.2 0.1 0.0 0.0 0.0 0.0 33.0 0.1 0.0 0.5 0.0 0.0 14.7 0.0 0.1 0.0 0.3 62.6 0.1 9.8 0.2 2.1 1.6 0.0 0.0 9816.7 0.0 0.0 3.1 0.0 0.2 0.0 12.3 1.1 0.2 0.2 0.0 1982.4 0.6 0.0 0.0 0.0 4.2 0.0 0.5 3.6 119.9 0.6 45.9 0.0 5175.8 91.4 0.0 7.8 0.0 0.0 0.0 0.4 15.2 0.0 12.6 0.0 0.2 0.4 0.1 0.7 0.1 0.1 0.1 0.1 14.5 0.7 0.1 KLF7 UKLF ENSG00000118263 "Kruppel like factor 7" O75840 2 207074137-207167267 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 95.2;Oligodendrocytes: 160.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 46.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003423, HPA030490" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "HPA003423: , HPA030490: AB_10601922" "unprognostic (5.93e-2)" "unprognostic (2.49e-3)" "unprognostic (2.98e-1)" "unprognostic (3.99e-3)" "unprognostic (2.56e-1)" "unprognostic (2.85e-3)" "unprognostic (5.44e-2)" "unprognostic (1.24e-2)" "unprognostic (6.75e-2)" "unprognostic (8.78e-2)" "unprognostic (3.67e-2)" "unprognostic (1.47e-1)" "prognostic favorable (4.26e-4)" "unprognostic (3.27e-3)" "unprognostic (1.23e-1)" "unprognostic (1.73e-1)" "unprognostic (3.47e-2)" 19.9 8.2 8.2 13.8 15.0 40.3 15.0 19.3 9.1 8.9 0.0 11.4 4.6 16.9 5.9 9.7 10.0 11.8 10.1 8.3 13.4 7.9 7.1 15.2 7.7 20.2 17.0 14.2 5.1 3.0 4.9 5.8 20.9 8.2 5.3 4.7 7.4 7.4 4.9 6.8 10.3 20.9 12.1 10.3 9.1 6.8 17.4 14.3 8.8 7.4 7.3 9.8 9.8 20.3 8.8 6.1 16.3 1.1 5.6 14.4 3.4 10.0 8.0 15.3 6.7 0.1 7.1 0.1 6.3 20.6 26.5 21.5 13.9 46.2 8.2 6.0 0.8 0.2 18.5 3.5 9.7 4.6 6.7 19.3 15.3 10.7 35.0 22.0 18.1 4.6 0.0 8.2 11.8 0.2 5.6 1.7 9.7 0.9 3.0 2.4 4.3 6.4 3.7 6.8 25.0 30.5 8.6 12.0 7.8 13.0 2.0 6.9 35.9 30.3 14.5 12.9 12.0 6.2 4.5 0.0 26.7 3.8 6.1 28.9 9.4 12.3 1.6 12.1 0.6 5.7 8.4 1.6 5.3 7.7 14.3 9.9 40.8 22.9 22.7 2.4 7.7 6.1 8.2 15.0 19.3 9.1 8.3 13.4 20.2 17.0 20.9 12.1 17.4 20.3 95.2 41.7 6.7 74.4 15.8 21.9 23.1 35.0 6.2 9.0 9.9 11.4 17.6 14.3 15.1 9.2 12.5 0.5 6.9 0.4 1.9 22.7 10.2 13.9 33.7 65.8 6.0 2.5 46.4 51.5 0.8 22.0 11.7 17.3 12.0 3.6 79.9 14.7 15.6 11.8 31.1 2.6 34.6 50.0 22.9 5.2 13.7 37.6 3.6 61.8 28.3 7.1 8.2 68.9 160.5 79.9 1.4 10.1 4.3 9.2 14.1 4.3 9.8 8.7 46.0 38.6 42.0 0.8 14.8 8.1 15.3 1.1 7.6 7.9 4.3 9.3 KLHL5 ENSG00000109790 "Kelch like family member 5" Q96PQ7 4 39045039-39126857 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 186.3;Microglial cells: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 323.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013958 Approved NA NA "Cluster 6: Non-specific - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA013958: AB_1852590" "unprognostic (6.02e-2)" "unprognostic (3.94e-1)" "unprognostic (3.92e-1)" "unprognostic (7.54e-3)" "unprognostic (5.35e-2)" "unprognostic (3.43e-1)" "unprognostic (2.48e-2)" "unprognostic (3.98e-2)" "unprognostic (2.70e-1)" "unprognostic (1.10e-1)" "unprognostic (6.04e-2)" "unprognostic (2.87e-2)" "unprognostic (1.42e-2)" "unprognostic (1.05e-2)" "unprognostic (2.28e-1)" "unprognostic (1.36e-1)" "unprognostic (3.24e-3)" 41.4 22.4 53.9 32.3 53.8 9.0 18.7 44.8 56.5 17.0 29.4 44.4 12.7 19.1 13.5 32.0 9.4 23.1 14.4 49.8 50.0 25.0 42.3 20.2 33.7 53.5 50.2 18.4 11.3 12.9 7.5 28.0 53.0 35.9 16.1 11.8 10.2 66.0 10.7 6.1 13.2 46.1 56.7 21.0 13.1 11.0 55.2 14.6 21.5 18.9 38.9 34.8 9.5 52.6 56.7 78.2 40.9 30.2 22.9 58.5 59.1 44.2 323.1 36.6 35.4 64.6 40.4 86.4 52.4 45.5 192.7 3.3 50.7 112.3 46.6 8.8 10.1 36.8 71.4 46.5 195.6 10.9 11.9 74.5 61.9 55.5 137.7 134.1 73.7 13.8 28.2 17.0 87.1 23.8 11.5 19.6 12.6 14.3 75.5 20.9 53.7 2.1 31.3 23.0 2.8 29.7 25.0 8.0 21.8 49.0 19.3 22.9 94.2 96.8 65.4 25.5 53.8 19.3 18.7 79.0 78.6 28.3 22.9 5.4 2.2 0.4 0.7 3.2 1.1 5.1 1.4 0.8 2.5 3.7 1.1 0.5 2.3 1.0 1.4 0.9 0.2 0.8 53.9 53.8 44.8 56.5 49.8 50.0 53.5 50.2 53.0 56.7 55.2 52.6 74.9 16.0 1.1 45.7 38.0 3.7 9.4 22.9 7.4 18.8 16.5 11.2 4.5 17.2 33.7 11.0 4.2 1.0 6.3 0.3 17.6 39.3 2.8 4.0 11.1 43.6 1.2 10.9 46.1 21.0 57.9 12.6 3.1 5.3 2.5 9.5 22.9 35.6 13.3 70.7 186.3 0.4 12.2 25.4 25.8 6.6 8.1 28.6 17.8 190.2 27.5 12.1 7.2 69.9 79.0 24.3 0.1 13.9 43.0 31.5 2.0 21.8 32.7 3.4 0.0 14.2 17.3 9.8 5.6 3.3 3.4 5.7 10.7 32.4 0.7 14.1 LAMA3 "BM600-150kDa, epiligrin, kalinin-165kDa, LAMNA, nicein-150kDa" ENSG00000053747 "Laminin subunit alpha 3" Q16787 18 23689453-23956222 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Epidermolysis bullosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 171.0;Gastric mucus-secreting cells: 138.1;Pancreatic endocrine cells: 585.5;Paneth cells: 170.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 40.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "HBEC3-KT: 1237.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA009309, CAB010757" Uncertain Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 1800000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum" "CAB010757: AB_477162, HPA009309: AB_1079224" "unprognostic (1.49e-2)" "unprognostic (2.14e-2)" "unprognostic (6.36e-2)" "unprognostic (3.82e-3)" "unprognostic (2.08e-1)" "unprognostic (1.11e-1)" "unprognostic (1.83e-1)" "unprognostic (2.28e-3)" "unprognostic (1.59e-1)" "unprognostic (7.09e-3)" "prognostic unfavorable (3.58e-6)" "unprognostic (1.98e-1)" "unprognostic (2.36e-1)" "unprognostic (3.15e-1)" "unprognostic (9.91e-3)" "unprognostic (3.98e-2)" "unprognostic (1.13e-1)" 10.0 1.2 8.3 8.5 3.6 0.1 20.3 2.8 5.9 15.4 5.4 13.6 17.8 15.6 4.7 14.5 12.0 7.4 4.2 4.1 3.5 3.2 1.7 20.9 4.1 3.8 5.9 5.7 4.7 10.9 3.0 24.8 3.6 12.2 8.4 3.7 21.3 13.5 2.0 32.1 19.7 6.9 3.5 0.8 31.8 3.3 4.3 9.5 2.3 1.7 4.1 12.2 23.1 2.9 140.5 15.7 0.1 0.1 6.9 1.3 0.3 2.6 1.8 1.3 1.7 5.4 159.5 0.1 17.3 1.8 0.4 248.5 0.2 1237.9 0.9 0.2 8.8 0.0 5.6 2.8 1.2 0.0 0.6 1.6 139.1 0.8 140.0 0.9 5.2 0.2 0.0 0.2 1.6 0.4 0.1 0.1 1.4 42.6 14.4 2.6 0.1 0.2 51.8 15.4 0.6 2.5 4.9 2.0 0.4 0.3 4.5 1.8 12.3 0.9 1.0 6.7 0.6 0.2 0.1 0.6 2.9 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.3 3.6 2.8 5.9 4.1 3.5 3.8 5.9 3.6 3.5 4.3 2.9 28.8 115.4 26.4 13.1 0.7 31.4 104.2 117.1 100.7 6.0 21.8 41.8 2.3 4.3 20.4 1.8 0.0 0.6 0.5 171.0 0.0 30.2 3.9 21.5 4.3 7.5 8.3 0.0 8.3 34.4 0.4 3.6 138.1 24.0 5.7 9.5 2.5 0.9 0.2 0.0 18.5 23.7 4.1 0.0 1.5 4.5 5.9 2.0 1.8 68.4 0.6 0.2 0.0 1.0 2.0 585.5 170.1 3.4 0.2 45.6 39.5 0.0 15.6 2.2 6.6 1.5 22.1 4.5 4.0 28.2 9.9 0.1 1.5 5.9 28.4 18.2 LAYN "FLJ30977, FLJ31092" ENSG00000204381 Layilin Q6UX15 11 111540280-111561745 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Prostatic glandular cells: 233.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 22 "myeloid DC: 11.2;T-reg: 13.4" "Group enriched" "Detected in many" 123 "dendritic cells: 11.2;T-cells: 13.4" "Cell line enhanced" "Detected in many" "BJ: 150.7;BJ hTERT+: 153.7;BJ hTERT+ SV40 Large T+ RasG12V: 96.7;fHDF/TERT166: 95.1;HSkMC: 88.8;hTERT-RPE1: 94.0;U-138 MG: 108.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA040087 Approved Approved Cytosol NA NA 340000 "Cluster 35: T-regs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA040087: AB_10793927" "unprognostic (2.27e-1)" "unprognostic (3.03e-2)" "unprognostic (2.22e-3)" "unprognostic (1.96e-1)" "unprognostic (3.90e-2)" "unprognostic (1.83e-2)" "unprognostic (5.62e-3)" "unprognostic (1.99e-1)" "unprognostic (1.38e-1)" "unprognostic (7.75e-3)" "unprognostic (4.47e-2)" "unprognostic (1.18e-1)" "unprognostic (1.61e-2)" "unprognostic (5.01e-2)" "unprognostic (1.65e-1)" "unprognostic (2.91e-2)" "unprognostic (1.35e-2)" 10.7 2.0 15.6 5.7 21.4 1.0 8.5 15.7 19.6 15.6 13.7 29.2 3.8 15.8 10.1 4.7 17.7 17.0 7.0 16.6 17.1 5.7 0.9 11.3 7.1 17.4 19.7 39.1 2.0 6.4 6.2 14.1 16.3 14.6 3.3 0.8 5.5 17.0 6.1 2.6 10.6 22.5 14.2 8.2 13.1 4.4 18.0 10.3 27.4 6.1 5.0 8.8 12.2 23.7 0.4 3.9 0.8 0.0 25.4 48.0 7.6 150.7 153.7 71.0 96.7 0.2 0.1 0.0 1.4 95.1 18.7 3.2 9.9 0.7 74.2 0.2 0.5 0.8 0.0 0.2 41.7 0.0 0.2 88.8 0.0 30.8 0.2 94.0 0.9 0.0 0.0 0.1 29.4 0.0 0.1 0.1 4.8 0.0 0.0 0.0 11.4 0.2 0.6 0.0 4.9 18.9 0.5 0.2 0.4 34.9 0.1 0.7 0.6 108.8 81.2 1.0 74.3 0.0 0.0 0.2 14.4 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 11.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 13.4 0.4 15.6 21.4 15.7 19.6 16.6 17.1 17.4 19.7 16.3 14.2 18.0 23.7 22.2 19.2 2.8 0.3 0.3 2.2 48.8 44.8 0.6 0.4 0.7 15.0 2.7 2.8 23.3 0.0 0.0 1.6 2.6 0.0 0.0 6.5 2.5 3.9 7.7 50.9 0.0 2.7 0.3 0.2 2.1 13.1 0.0 0.9 1.3 9.6 6.8 0.1 0.7 0.0 1.4 0.0 6.1 0.6 13.6 1.8 22.7 1.2 0.0 2.8 0.6 0.2 0.0 4.0 30.1 0.8 0.0 55.3 2.8 233.0 0.0 0.2 32.0 0.2 32.9 2.6 17.3 0.1 2.3 0.1 2.3 0.5 14.5 11.2 0.0 50.3 LDB2 "CLIM1, LDB1" ENSG00000169744 "LIM domain binding 2" O43679 4 16501541-16898678 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 236.5;Endothelial cells: 194.4;Excitatory neurons: 1314.4;Hepatic stellate cells: 364.8;Inhibitory neurons: 196.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "NK-cell: 2.0" "Lineage enriched" "Detected in single" 13 "NK-cells: 2.0" "Cell line enhanced" "Detected in many" "AF22: 18.3;fHDF/TERT166: 19.0;HAP1: 34.4;HUVEC TERT2: 65.3;TIME: 17.1;U-138 MG: 25.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017544, HPA068634" Supported Supported "Nucleoplasm,Nucleoli,Plasma membrane" No NA "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nucleoli" "Plasma membrane" "CAB017544: AB_2137013, HPA068634: AB_2686012" "unprognostic (3.43e-1)" "unprognostic (2.77e-1)" "unprognostic (9.10e-2)" "unprognostic (4.37e-1)" "unprognostic (7.25e-2)" "unprognostic (4.62e-3)" "unprognostic (2.10e-3)" "unprognostic (1.57e-1)" "unprognostic (2.94e-2)" "unprognostic (2.82e-1)" "unprognostic (2.67e-2)" "unprognostic (1.96e-2)" "unprognostic (2.05e-3)" "unprognostic (1.26e-3)" "unprognostic (1.60e-1)" "unprognostic (9.63e-2)" "unprognostic (7.10e-3)" 58.9 15.5 13.7 8.0 19.8 0.4 52.2 3.3 45.9 43.5 7.6 12.7 6.5 65.5 23.4 15.8 28.0 31.2 33.7 23.3 7.3 28.0 26.0 58.2 11.5 4.4 10.9 18.2 7.6 17.0 9.0 58.8 4.7 18.0 8.5 5.3 10.8 13.7 14.0 9.4 12.8 53.8 7.1 50.4 11.5 5.0 7.9 8.3 31.3 24.3 4.8 22.5 22.8 19.7 0.0 0.0 18.3 0.1 10.5 16.9 0.0 10.2 8.0 1.2 2.7 0.0 0.0 0.0 0.0 19.0 0.0 0.0 34.4 0.0 7.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 9.5 0.0 12.5 0.0 2.7 65.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.7 0.0 0.1 8.8 0.0 0.0 0.8 0.0 0.0 2.3 0.0 0.0 0.0 4.9 0.0 0.0 17.1 25.7 0.1 1.2 0.0 8.3 0.1 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.2 13.7 19.8 3.3 45.9 23.3 7.3 4.4 10.9 4.7 7.1 7.9 19.7 236.5 0.0 5.5 44.7 1.5 8.7 0.3 0.0 2.8 27.1 1.7 2.2 8.7 2.8 0.0 0.0 0.0 0.2 6.8 0.0 0.0 4.4 1.3 1.4 36.5 194.4 0.0 8.0 1314.4 0.2 0.2 44.4 4.1 1.1 5.7 0.1 364.8 3.1 0.4 0.0 196.5 0.0 0.0 16.4 13.2 2.6 38.2 1.4 8.8 117.1 0.0 10.4 3.1 120.6 36.7 0.2 0.0 50.4 0.0 0.3 0.0 0.1 0.7 2.1 6.6 2.8 19.3 0.2 0.7 1.3 6.8 0.1 4.9 39.7 0.0 0.5 LETM2 "FLJ25409, SLC55A2" ENSG00000165046 "Leucine zipper and EF-hand containing transmembrane protein 2" Q2VYF4 8 38386207-38409527 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 23.8" "Cell type enhanced" "Detected in many" "Early spermatids: 76.9;Late spermatids: 57.6;Pancreatic endocrine cells: 48.6;Spermatocytes: 54.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 21.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 21.5" "Cell line enhanced" "Detected in many" "HBEC3-KT: 25.2;hTERT-HME1: 26.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 24.0" HPA025032 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 78: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Nuclear bodies, Cytosol" "HPA025032: AB_1852808" "unprognostic (3.37e-2)" "unprognostic (2.73e-1)" "unprognostic (3.14e-1)" "unprognostic (2.05e-2)" "unprognostic (2.27e-4)" "unprognostic (3.20e-2)" "unprognostic (3.96e-2)" "unprognostic (1.43e-1)" "unprognostic (8.27e-2)" "unprognostic (3.80e-2)" "unprognostic (1.39e-1)" "unprognostic (1.35e-1)" "unprognostic (3.40e-2)" "unprognostic (4.09e-3)" "unprognostic (2.49e-1)" "unprognostic (1.16e-1)" "unprognostic (9.25e-2)" 1.2 1.0 3.4 1.1 3.6 5.3 0.7 5.7 4.9 1.6 2.9 0.7 0.8 1.4 1.1 1.1 1.4 1.2 0.8 3.2 2.8 2.3 0.7 2.0 1.3 2.3 2.9 2.1 0.7 1.6 1.3 1.8 3.1 1.1 0.8 4.2 0.4 0.8 0.2 1.1 0.5 0.6 2.0 1.6 2.7 23.8 2.6 2.4 1.0 0.3 1.4 1.9 0.6 4.2 21.2 4.5 3.0 2.9 2.3 7.0 2.5 7.5 9.2 10.6 6.2 1.5 8.3 2.8 16.5 1.5 3.1 2.2 5.9 25.2 11.7 1.2 2.9 3.2 2.3 4.2 2.7 0.7 2.8 1.7 7.2 11.7 26.9 5.9 10.7 3.4 2.6 3.9 9.3 4.2 7.5 1.8 0.8 1.6 18.2 2.9 4.8 1.6 16.8 1.1 2.4 2.3 2.5 0.4 0.9 1.8 2.4 1.2 20.0 3.3 22.5 7.4 1.7 2.6 1.6 2.0 5.6 3.3 2.5 1.3 4.1 0.7 0.9 1.6 2.0 1.5 0.9 1.5 1.7 1.8 1.7 1.7 21.5 1.4 5.0 0.7 5.2 1.3 3.4 3.6 5.7 4.9 3.2 2.8 2.3 2.9 3.1 2.0 2.6 4.2 3.0 3.2 6.4 2.3 10.3 0.5 13.9 7.6 6.8 6.6 2.1 3.3 1.8 4.3 3.2 5.5 6.2 2.6 10.1 1.4 1.9 4.0 76.9 21.8 7.1 4.2 0.0 0.8 3.6 20.5 7.9 5.0 16.8 20.5 9.5 1.1 1.4 0.0 1.4 6.7 7.3 1.9 2.0 2.2 2.3 57.6 2.1 3.6 1.8 1.0 2.0 3.6 1.0 1.5 1.6 48.6 0.1 1.5 4.5 2.9 0.3 3.0 4.9 8.4 0.0 4.5 3.3 54.8 3.3 2.5 0.9 8.1 9.1 1.5 1.3 4.5 LGALS8 PCTA-1 ENSG00000116977 "Galectin 8" O00214 1 236518000-236552981 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 322.8;Late spermatids: 222.6;Syncytiotrophoblasts: 176.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 118.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012734, HPA030491" Approved Approved "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" "HPA012734: AB_2668720, HPA030491: AB_10602345" "unprognostic (2.03e-2)" "unprognostic (1.54e-1)" "unprognostic (2.38e-2)" "unprognostic (3.80e-3)" "unprognostic (2.02e-3)" "unprognostic (4.71e-3)" "unprognostic (3.93e-2)" "prognostic favorable (9.40e-4)" "unprognostic (9.96e-2)" "unprognostic (1.41e-1)" "unprognostic (2.12e-1)" "unprognostic (1.78e-3)" "prognostic unfavorable (4.93e-7)" "unprognostic (1.41e-1)" "unprognostic (1.57e-1)" "unprognostic (3.15e-2)" "unprognostic (8.21e-2)" 28.6 14.3 10.8 26.5 11.3 44.4 23.3 12.4 14.1 17.2 11.5 19.9 21.6 16.7 19.6 21.2 13.8 24.8 55.0 12.5 12.6 23.4 49.5 27.0 24.0 12.9 10.9 21.6 21.8 35.0 12.7 41.0 13.5 22.2 19.9 22.9 22.1 21.3 6.8 32.4 24.1 21.8 11.7 42.6 18.9 57.1 11.4 26.3 17.2 9.4 22.8 32.8 15.3 11.7 52.3 27.5 3.6 20.8 46.6 39.0 55.6 38.0 45.4 49.0 59.3 37.6 63.3 1.5 34.8 33.7 26.8 60.3 11.0 54.7 43.2 31.1 7.3 35.5 20.7 68.1 56.9 46.9 78.9 39.6 45.6 41.0 13.8 42.4 52.5 26.4 40.7 25.1 35.7 33.3 23.2 8.4 12.5 4.1 18.5 27.2 0.8 3.0 35.4 80.8 13.1 25.7 24.4 82.3 13.7 2.1 59.0 33.7 39.1 1.0 22.0 29.9 47.7 10.0 7.4 1.0 50.4 65.7 30.9 118.5 37.4 18.7 12.5 32.9 17.8 10.7 18.4 14.1 31.7 6.8 12.2 12.7 16.1 14.2 24.0 14.2 22.5 24.8 10.8 11.3 12.4 14.1 12.5 12.6 12.9 10.9 13.5 11.7 11.4 11.7 44.0 76.9 54.7 12.1 19.3 32.5 28.5 64.9 44.9 28.1 31.7 22.7 55.2 34.3 68.1 14.7 25.0 64.4 33.9 25.3 5.9 61.8 322.8 18.7 21.9 39.9 18.1 19.0 31.5 39.2 53.5 35.2 23.0 20.8 109.4 38.0 46.1 27.1 57.5 38.7 37.0 18.8 57.0 100.5 23.6 222.6 23.6 45.1 7.2 24.4 38.7 6.5 17.5 18.1 16.7 44.0 36.0 13.9 15.1 20.6 26.4 14.5 53.1 19.4 26.3 22.5 19.6 46.8 8.7 21.3 37.1 176.2 34.4 22.8 17.1 24.4 LMO2 "RBTN2, RBTNL1, RHOM2, TTG2" ENSG00000135363 "LIM domain only 2" P25791 11 33858576-33892076 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 109.2;Endothelial cells: 144.6;Erythroid cells: 103.7;Hepatic stellate cells: 167.4;Kupffer cells: 65.0;Microglial cells: 64.6" "Cancer enhanced" "Detected in all" "glioma: 30.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 6 "dendritic cells: 1.9;granulocytes: 1.5;monocytes: 1.7" "Cell line enhanced" "Detected in some" "HEL: 71.8;HL-60: 72.7;K-562: 60.9;NB-4: 27.3;THP-1: 81.6;U-937: 29.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016258, HPA029285, HPA070901, HPA070910" Approved Enhanced Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 32: U-937 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB016258: AB_2136572, HPA029285: AB_2672978, HPA070901: , HPA070910: " "unprognostic (1.60e-1)" "unprognostic (1.47e-2)" "unprognostic (6.03e-2)" "unprognostic (1.71e-3)" "unprognostic (1.89e-1)" "unprognostic (1.14e-3)" "prognostic favorable (3.12e-4)" "unprognostic (1.73e-3)" "unprognostic (8.95e-2)" "unprognostic (5.76e-2)" "unprognostic (7.86e-3)" "unprognostic (3.69e-1)" "unprognostic (7.10e-2)" "unprognostic (9.65e-2)" "unprognostic (3.90e-1)" "unprognostic (1.45e-1)" "unprognostic (4.46e-2)" 15.0 5.9 14.9 11.4 13.0 27.7 12.5 14.2 16.6 8.4 13.4 5.0 4.6 6.5 0.7 6.8 8.3 5.4 4.4 14.7 16.0 13.1 2.3 18.2 19.4 19.9 16.3 3.5 2.6 2.3 8.6 6.5 18.5 5.7 1.5 0.6 5.3 2.4 23.4 4.9 6.6 4.8 18.7 19.0 3.9 1.7 19.0 1.8 12.3 4.6 8.4 5.8 7.3 13.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.0 2.2 1.3 12.8 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.4 71.8 0.0 0.0 0.3 72.7 18.5 0.0 0.0 0.0 0.0 0.0 10.2 0.0 60.9 0.0 0.0 0.3 5.1 27.3 0.9 0.0 0.0 15.3 0.8 0.2 0.0 0.8 4.3 0.0 0.3 0.5 0.1 0.2 0.0 81.6 0.9 0.0 0.2 1.7 0.0 0.0 0.2 0.6 4.7 29.2 0.3 0.6 0.5 1.5 0.0 1.4 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.7 0.0 1.7 0.1 0.0 0.2 14.9 13.0 14.2 16.6 14.7 16.0 19.9 16.3 18.5 18.7 19.0 13.3 109.2 3.2 7.1 8.5 6.6 8.4 7.9 8.0 0.6 1.6 2.8 9.5 2.8 8.6 1.7 5.5 2.1 0.4 1.0 0.8 0.0 3.0 0.5 40.5 11.0 144.6 0.0 103.7 1.3 2.0 3.2 9.8 0.0 39.6 7.6 0.9 167.4 1.7 39.1 0.0 3.8 0.2 2.0 65.0 56.8 1.2 4.1 54.1 10.6 64.6 47.5 1.1 4.1 5.0 1.0 1.0 1.9 0.0 3.0 5.4 0.0 8.8 5.0 2.6 0.0 17.3 3.6 0.3 7.9 0.8 6.0 21.5 1.9 12.4 0.5 25.1 LRP2BP DKFZp761O0113 ENSG00000109771 "LRP2 binding protein" Q9P2M1 4 185363872-185395924 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 28.9" "Cell type enhanced" "Detected in many" "Astrocytes: 57.5;Cone photoreceptor cells: 33.3;Early spermatids: 62.1;Inhibitory neurons: 34.2;Late spermatids: 42.3;Oligodendrocyte precursor cells: 40.2;Oligodendrocytes: 34.9;Rod photoreceptor cells: 34.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "U-266/70: 5.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036664, HPA036665" Approved NA NA "Cluster 37: B-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 29: U-266 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA036664: AB_10672361, HPA036665: AB_10673660" "unprognostic (2.50e-1)" "unprognostic (1.18e-1)" "unprognostic (2.64e-3)" "unprognostic (3.15e-5)" "unprognostic (2.12e-2)" "unprognostic (1.30e-1)" "unprognostic (1.61e-1)" "unprognostic (9.53e-3)" "unprognostic (1.46e-1)" "unprognostic (5.84e-2)" "unprognostic (4.35e-4)" "unprognostic (2.17e-2)" "unprognostic (9.76e-3)" "unprognostic (2.15e-1)" "unprognostic (5.26e-3)" "unprognostic (1.29e-1)" "unprognostic (4.54e-4)" 1.7 2.1 6.7 0.7 6.9 0.4 1.6 15.0 7.9 2.7 9.8 3.6 0.3 1.8 2.3 1.0 6.9 0.9 3.6 6.5 7.5 4.8 1.6 4.4 0.7 11.4 10.0 8.5 3.2 0.2 17.4 0.6 8.7 3.7 0.4 28.9 1.5 0.5 3.0 1.5 1.9 0.3 9.8 2.7 1.7 10.7 8.1 0.2 3.5 0.7 0.1 2.1 1.7 10.8 0.5 0.4 0.5 1.1 0.3 0.1 1.0 1.5 0.4 0.0 0.3 0.5 0.5 1.8 0.1 0.1 0.5 0.3 0.3 0.2 0.2 1.7 0.9 0.4 1.5 1.6 0.2 0.3 0.5 0.3 0.2 0.7 0.2 1.5 0.4 1.3 0.6 1.4 0.4 0.1 0.6 1.2 0.6 0.0 0.2 0.3 0.3 0.4 0.4 0.3 1.2 0.8 0.3 0.4 1.0 0.7 0.4 0.1 1.4 0.8 0.6 0.2 0.8 5.3 0.5 0.3 1.3 0.3 0.6 0.0 0.0 0.0 0.2 0.0 0.1 0.5 0.2 0.2 0.0 0.5 0.3 0.2 0.1 0.1 0.1 0.5 0.2 0.0 6.7 6.9 15.0 7.9 6.5 7.5 11.4 10.0 8.7 9.8 8.1 10.8 3.1 9.6 2.6 57.5 3.5 2.4 4.1 1.3 2.8 28.8 3.0 2.4 5.5 0.0 1.8 0.0 33.3 1.2 3.3 1.7 0.0 1.5 62.1 17.6 3.1 3.2 7.8 0.0 28.0 0.9 2.5 2.1 2.6 4.4 0.0 1.9 1.4 0.3 0.5 26.9 34.2 2.4 4.1 1.2 1.4 42.3 2.8 1.9 5.4 3.7 0.8 10.4 0.0 40.2 34.9 1.0 0.2 3.8 2.5 4.3 2.6 1.6 14.1 34.0 0.0 5.4 2.8 8.4 1.9 0.8 3.1 1.6 3.1 2.1 1.0 2.1 LRRC32 "D11S833E, GARP" ENSG00000137507 "Leucine rich repeat containing 32" Q14392 11 76657524-76670747 "Predicted intracellular proteins, Predicted membrane proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 78.0;Endothelial cells: 88.3;Extravillous trophoblasts: 164.2;Hepatic stellate cells: 95.3;Sertoli cells: 39.5;Smooth muscle cells: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 2.2" "Lineage enhanced" "Detected in single" "T-cells: 2.2" "Group enriched" "Detected in some" 6 "ASC diff: 115.0;ASC TERT1: 70.3;HSkMC: 44.0;HUVEC TERT2: 51.4;U-2197: 108.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055775, HPA058434" Enhanced Nucleoplasm "Intracellular and membrane" NA NA 98000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA055775: AB_2732600, HPA058434: AB_2732622" "unprognostic (3.18e-1)" "unprognostic (1.38e-1)" "unprognostic (2.60e-2)" "unprognostic (4.19e-3)" "unprognostic (1.16e-1)" "unprognostic (8.84e-2)" "unprognostic (1.39e-2)" "unprognostic (2.24e-2)" "unprognostic (6.29e-2)" "unprognostic (1.83e-2)" "unprognostic (1.58e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (3.93e-5)" "unprognostic (7.99e-3)" "unprognostic (1.15e-2)" "unprognostic (5.22e-3)" "prognostic unfavorable (2.64e-4)" 104.5 34.3 12.6 10.5 12.6 2.4 63.6 11.2 11.8 56.2 8.4 23.2 8.9 36.4 6.2 10.3 31.6 29.0 55.7 9.6 10.6 64.7 11.3 109.0 4.3 12.2 13.8 13.5 12.0 7.5 16.7 53.0 13.0 24.9 6.1 1.3 12.8 11.0 23.6 26.6 21.4 15.2 10.9 28.9 21.3 3.6 15.0 2.0 42.3 6.2 1.5 36.7 28.8 11.5 0.0 0.0 1.3 0.0 115.0 70.3 1.4 0.4 0.8 0.1 0.1 0.0 0.0 0.2 3.1 1.9 0.0 0.1 0.2 0.0 0.1 0.0 0.0 11.8 0.6 0.0 2.2 0.0 0.1 44.0 0.0 4.1 0.2 0.9 51.4 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 7.6 0.2 0.0 13.8 7.5 0.8 108.3 0.0 0.1 0.0 1.9 5.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.2 4.3 12.6 12.6 11.2 11.8 9.6 10.6 12.2 13.8 13.0 10.9 15.0 11.5 78.0 0.0 4.3 0.0 1.7 14.5 0.3 0.0 1.8 0.0 0.6 0.6 10.4 0.0 1.3 0.0 0.0 1.9 0.1 0.2 0.0 0.3 1.3 0.1 1.9 88.3 0.0 5.3 0.0 0.0 164.2 26.4 0.5 0.3 2.5 0.5 95.3 0.6 3.6 0.0 0.1 0.4 0.0 3.1 19.0 1.9 9.0 2.9 17.8 14.0 0.0 0.4 0.0 0.0 0.1 0.0 2.2 9.1 0.2 1.4 0.0 0.4 0.7 0.1 39.5 2.1 47.6 0.4 4.7 0.6 12.5 8.3 1.6 0.4 0.1 1.2 LRRC39 "MGC14816, myomasp" ENSG00000122477 "Leucine rich repeat containing 39" Q96DD0 1 100148448-100178273 "Predicted intracellular proteins" "Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 107.0;retina: 117.9;skeletal muscle: 431.0;tongue: 172.9" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 96.4;Cone photoreceptor cells: 60.5;Early spermatids: 204.8;Hofbauer cells: 76.4;Inhibitory neurons: 62.2;Rod photoreceptor cells: 74.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-MEL-30: 6.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA077159 Enhanced NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA077159: AB_2732333" "unprognostic (7.68e-2)" "unprognostic (3.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.91e-1)" "unprognostic (6.40e-2)" "unprognostic (1.27e-1)" "unprognostic (4.07e-3)" "unprognostic (1.58e-2)" "unprognostic (1.87e-2)" "unprognostic (1.45e-1)" "unprognostic (3.16e-3)" "unprognostic (3.08e-2)" "unprognostic (1.02e-1)" "unprognostic (2.64e-1)" "unprognostic (8.17e-2)" "unprognostic (1.79e-1)" "unprognostic (3.38e-4)" 2.2 9.8 3.5 1.5 3.6 1.5 1.9 2.8 4.7 1.6 1.1 1.8 1.0 1.4 1.4 4.2 1.7 1.1 107.0 2.8 3.7 1.7 2.6 1.7 2.4 3.8 2.9 1.6 1.6 5.3 2.3 4.2 2.5 4.2 0.6 117.9 2.9 0.5 431.0 3.8 1.7 0.7 1.8 2.3 1.6 6.5 4.2 1.1 1.9 172.9 0.9 1.7 1.3 3.6 0.4 0.5 1.8 2.4 0.4 0.8 1.5 0.8 0.3 0.3 0.7 0.1 1.1 2.0 0.9 0.3 0.4 1.1 0.2 0.2 0.7 0.3 1.7 0.9 2.4 0.4 0.2 0.6 1.1 1.5 0.3 0.3 0.1 0.5 0.3 1.5 0.9 1.7 0.5 0.3 1.0 2.4 0.8 0.5 0.6 1.0 0.8 0.8 0.3 0.6 0.7 2.5 0.5 0.7 6.7 0.6 0.6 1.4 0.5 1.0 0.9 1.3 1.6 3.2 1.6 0.7 1.7 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.6 2.8 4.7 2.8 3.7 3.8 2.9 2.5 1.8 4.2 3.6 0.3 0.0 1.3 6.8 0.4 0.1 0.1 0.0 0.0 13.1 0.3 0.1 96.4 0.0 0.0 0.0 60.5 0.5 0.3 0.3 0.0 0.2 204.8 0.2 0.5 1.8 0.0 0.0 14.6 0.6 0.6 3.8 0.0 0.5 1.3 0.2 0.7 0.2 76.4 18.5 62.2 0.0 0.0 0.3 0.0 21.7 2.1 8.0 0.0 1.9 0.8 8.1 1.0 5.5 10.2 0.3 0.1 0.4 0.5 0.1 0.0 0.0 0.7 74.2 0.0 8.6 1.4 9.9 1.2 0.0 0.1 0.7 0.4 0.4 0.0 0.0 LRRC70 "LOC100130733, SLRN" ENSG00000186105 "Leucine rich repeat containing 70" Q7Z2Q7 5 62578819-62581446 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 3.6;Endothelial cells: 4.9;Erythroid cells: 1.7;Fibroblasts: 1.8;granulocytes: 3.8;Hepatic stellate cells: 3.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "HUVEC TERT2: 17.6;TIME: 9.6" "Low region specificity" "Detected in all" HPA013409 Uncertain NA NA 17000 "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA013409: AB_10601911" "unprognostic (1.60e-1)" "unprognostic (1.27e-2)" "unprognostic (4.04e-1)" "unprognostic (1.69e-1)" "unprognostic (5.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.17e-4)" "unprognostic (3.03e-1)" "unprognostic (3.77e-2)" "unprognostic (1.60e-1)" "unprognostic (2.19e-1)" "unprognostic (4.15e-1)" "unprognostic (7.40e-4)" "unprognostic (5.67e-3)" "unprognostic (1.02e-1)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" 4.7 0.8 0.5 1.4 0.4 3.6 4.7 0.5 1.2 3.9 0.6 1.4 0.8 1.9 1.0 1.7 3.3 3.6 1.8 0.4 0.4 1.9 1.4 1.9 1.9 0.7 0.8 2.9 0.9 1.2 1.4 4.6 0.6 2.0 1.4 1.0 1.2 0.5 0.7 2.7 1.4 3.4 0.6 4.1 1.1 1.7 0.5 1.0 4.0 0.6 0.7 1.7 2.8 0.8 0.2 0.0 0.2 0.1 0.5 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 17.6 0.3 0.2 0.7 0.0 0.1 0.5 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.1 0.1 0.1 0.0 9.6 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.5 0.4 0.5 1.2 0.4 0.4 0.7 0.8 0.6 0.6 0.5 0.8 3.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.1 0.1 4.9 0.0 1.7 0.0 0.0 0.0 1.8 0.0 0.1 3.8 0.1 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.4 0.3 0.0 0.3 0.0 0.0 0.0 LY6K "CT97, FLJ35226, HSJ001348" ENSG00000160886 "Lymphocyte antigen 6 family member K" Q17RY6 8 142700111-142705127 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 12.5;testis: 36.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 186.7;Prostatic glandular cells: 105.2;Spermatocytes: 404.4;Spermatogonia: 105.8;Urothelial cells: 131.4" "Cancer enhanced" "Detected in many" "cervical cancer: 11.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "neutrophil: 1.8" "Lineage enriched" "Detected in single" 14 "granulocytes: 1.8" "Cell line enhanced" "Detected in many" "A-431: 125.2;BJ: 131.9;HeLa: 142.4;SiHa: 206.3;U-2197: 273.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017770, CAB075742, CAB075743, CAB079929" Enhanced Approved "Nucleoplasm,Plasma membrane" "Secreted in male reproductive system" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 71: Testis - DNA repair" "Cluster 18: U-2197 - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Plasma membrane" Nucleoplasm "CAB075742: AB_2665748, CAB075743: AB_2665749, CAB079929: , HPA017770: AB_1853414" "unprognostic (1.25e-1)" "unprognostic (1.95e-2)" "unprognostic (1.48e-1)" "unprognostic (7.23e-3)" "unprognostic (3.47e-2)" "unprognostic (2.39e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (9.17e-5)" "unprognostic (4.18e-2)" "unprognostic (6.89e-2)" "unprognostic (9.75e-2)" "unprognostic (1.40e-1)" "unprognostic (5.27e-5)" "unprognostic (1.71e-1)" "unprognostic (1.46e-1)" "unprognostic (2.03e-1)" "unprognostic (4.61e-2)" 5.4 0.2 0.6 0.2 0.6 0.3 4.4 0.9 1.7 3.3 0.0 0.5 0.3 0.5 0.2 12.5 1.2 0.4 1.5 0.8 1.0 3.0 0.2 0.8 0.2 1.7 0.8 0.7 0.3 0.0 0.4 2.4 2.0 1.1 0.0 2.4 1.7 0.8 5.4 6.8 0.3 0.1 1.1 0.2 1.1 36.0 0.7 0.6 1.0 1.3 0.6 1.0 5.1 1.1 125.2 2.0 0.0 6.3 2.4 7.9 1.5 131.9 15.3 39.9 24.0 0.2 0.5 0.0 10.9 15.0 14.3 10.8 0.0 7.5 33.5 1.2 0.2 0.1 142.4 0.3 1.9 0.0 0.0 11.7 21.1 29.7 38.0 0.1 3.7 0.0 0.0 0.6 76.2 1.0 0.2 0.3 4.2 4.1 2.0 0.3 0.5 0.2 6.7 1.7 3.7 0.5 206.3 2.7 41.3 6.6 0.5 0.2 5.4 1.9 11.8 273.2 0.2 0.2 0.1 0.3 0.6 0.1 13.6 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.6 0.6 0.9 1.7 0.8 1.0 1.7 0.8 2.0 1.1 0.7 1.1 25.6 3.2 0.5 0.0 0.4 38.9 54.2 4.3 21.6 0.6 15.1 49.8 0.2 5.7 9.8 25.8 0.0 13.5 0.3 0.0 0.0 0.8 7.7 3.1 8.5 9.2 0.0 0.0 0.0 0.0 186.7 8.0 0.0 9.0 0.0 0.0 3.3 0.1 6.0 0.0 0.0 0.0 6.1 0.3 28.7 14.8 4.1 4.6 12.4 0.0 0.0 0.5 0.0 0.0 0.1 6.7 1.1 3.0 0.0 105.2 0.0 0.2 3.6 0.6 0.0 17.8 13.1 404.4 105.8 32.2 44.9 25.3 0.7 0.1 0.0 131.4 LYPD5 FLJ30469 ENSG00000159871 "LY6/PLAUR domain containing 5" Q6UWN5 19 43785874-43827206 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 50.6" "Cell type enhanced" "Detected in many" "Early spermatids: 33.0;Late spermatids: 81.8;Melanocytes: 17.8;Syncytiotrophoblasts: 21.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 3.5;BEWO: 5.0;HaCaT: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042511, HPA054670" Approved Approved Nucleoplasm,Cytosol No NA "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA042511: AB_10794279, HPA054670: AB_2682567" "unprognostic (4.27e-3)" "prognostic favorable (5.84e-4)" "unprognostic (4.63e-2)" "unprognostic (8.42e-3)" "unprognostic (4.80e-2)" "unprognostic (2.91e-3)" "unprognostic (3.96e-1)" "unprognostic (7.93e-3)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" "unprognostic (1.40e-3)" "unprognostic (1.19e-1)" "unprognostic (1.83e-3)" "unprognostic (8.30e-2)" "unprognostic (2.02e-1)" "unprognostic (7.53e-3)" "unprognostic (4.08e-2)" 1.1 0.6 2.6 1.4 2.5 0.1 2.9 1.8 6.0 9.3 0.0 2.3 0.1 0.9 1.4 11.4 0.8 1.1 1.5 3.0 2.9 3.0 0.4 4.0 0.7 6.8 3.2 0.4 0.3 0.6 1.6 1.0 6.6 1.3 0.8 2.0 3.1 0.8 0.2 50.6 1.2 1.1 1.7 4.8 1.0 3.8 4.1 0.9 1.4 0.4 1.7 1.9 9.0 4.1 3.5 0.0 0.2 0.0 0.0 0.0 5.0 0.0 0.0 0.5 0.6 0.4 1.2 0.2 0.7 0.4 1.4 5.2 0.0 0.7 0.3 0.6 0.0 0.1 0.4 0.0 1.5 0.1 0.0 1.7 1.5 0.2 0.7 0.0 0.2 0.1 0.1 0.1 0.0 0.2 0.1 0.0 0.3 1.9 1.2 0.0 0.0 0.0 0.3 0.6 0.2 0.1 0.7 0.7 0.0 1.1 0.4 0.1 0.3 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.3 0.0 0.0 0.1 2.6 2.5 1.8 6.0 3.0 2.9 6.8 3.2 6.6 1.7 4.1 4.1 0.5 0.0 0.0 4.6 0.0 3.6 2.6 1.6 4.0 1.4 1.8 1.5 0.7 0.0 0.4 0.0 0.0 1.6 0.1 3.7 3.9 0.6 33.0 0.2 0.1 3.1 0.0 0.0 7.7 0.9 8.4 1.2 0.0 0.2 0.0 0.5 0.7 0.0 2.4 0.0 8.8 1.9 0.0 0.6 0.8 81.8 0.3 0.5 17.8 1.0 0.0 0.9 0.0 9.5 7.8 0.3 2.3 1.2 0.0 1.4 0.2 0.0 1.4 0.9 0.0 1.0 0.2 9.9 2.6 3.7 2.8 21.6 0.1 0.1 0.8 6.2 MAFK "NFE2U, P18" ENSG00000198517 "MAF bZIP transcription factor K" O60675 7 1530702-1543043 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 94.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-2 OS: 82.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026820, HPA060841" Enhanced Enhanced Nucleoplasm No No "Cluster 46: Basophils - DNA binding" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB026820: , HPA060841: AB_2684377" "unprognostic (6.82e-2)" "unprognostic (3.71e-3)" "unprognostic (1.49e-2)" "unprognostic (2.55e-1)" "unprognostic (6.44e-3)" "unprognostic (1.19e-1)" "unprognostic (9.44e-2)" "unprognostic (2.28e-2)" "unprognostic (1.22e-2)" "unprognostic (1.45e-2)" "unprognostic (2.81e-1)" "unprognostic (1.40e-1)" "unprognostic (2.83e-2)" "unprognostic (1.08e-2)" "unprognostic (1.24e-1)" "unprognostic (5.59e-2)" "unprognostic (2.14e-1)" 40.9 31.0 37.0 13.0 34.8 19.5 34.4 26.8 34.8 30.9 38.2 61.1 18.2 34.7 1.8 30.1 33.6 11.6 80.5 26.8 28.0 50.3 32.8 60.0 9.4 35.5 33.3 21.7 39.7 4.2 25.6 25.4 32.2 49.2 4.7 2.4 25.6 10.7 78.6 38.6 31.1 6.7 30.2 21.0 37.2 9.7 35.6 22.9 27.3 13.1 4.9 39.4 35.7 43.2 50.0 35.0 1.2 5.2 3.9 4.8 26.2 32.3 18.3 7.7 5.4 25.2 13.4 11.6 11.7 8.2 51.8 38.1 2.9 9.2 3.3 17.9 25.2 6.8 50.8 18.7 8.7 16.2 20.7 4.8 11.8 12.9 9.6 9.5 7.1 35.7 17.8 6.2 3.6 32.7 18.2 57.6 11.2 12.2 35.2 27.1 1.2 19.5 7.3 20.2 14.8 5.4 19.5 56.4 14.6 7.5 22.0 21.3 16.8 11.8 82.3 59.5 17.9 11.8 3.9 19.8 15.5 22.0 17.1 0.5 0.4 1.2 0.6 0.2 0.6 0.3 0.3 0.7 0.2 0.5 0.7 0.5 0.6 0.5 0.5 1.5 0.7 0.4 37.0 34.8 26.8 34.8 26.8 28.0 35.5 33.3 32.2 30.2 35.6 43.2 33.0 41.7 17.6 2.0 8.8 63.9 52.2 21.3 37.0 2.2 33.7 20.2 2.8 11.5 25.7 31.3 2.1 11.0 13.2 45.8 1.9 15.2 2.9 57.3 13.3 24.6 23.2 8.2 8.8 14.9 9.0 16.6 20.4 94.3 9.5 6.6 9.7 14.8 10.9 11.8 3.7 24.4 16.2 13.2 27.9 6.0 4.7 18.0 19.6 9.4 8.7 7.1 8.2 0.5 3.1 46.2 38.9 3.0 6.0 60.8 27.4 2.5 29.6 1.6 13.1 33.2 27.1 0.9 4.0 25.8 57.7 78.0 11.0 2.0 19.8 73.5 MALL BENE ENSG00000144063 "Mal, T cell differentiation protein like" Q13021 2 110083870-110116022 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 368.5;intestine: 235.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 857.8;Ductal cells: 299.2;Pancreatic endocrine cells: 354.9;Paneth cells: 374.4;Proximal enterocytes: 742.2;Urothelial cells: 426.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 8.4;neutrophil: 2.5" "Lineage enriched" "Detected in many" 7 "granulocytes: 8.4" "Cell line enhanced" "Detected in many" "A-431: 267.4;A549: 269.9;CAPAN-2: 347.7;fHDF/TERT166: 380.9;HaCaT: 276.4;PC-3: 158.3" "Not detected" "Not detected" HPA051410 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA051410: AB_2681474" "unprognostic (5.17e-1)" "unprognostic (4.15e-2)" "unprognostic (2.92e-1)" "unprognostic (3.53e-1)" "unprognostic (1.92e-2)" "unprognostic (1.66e-1)" "unprognostic (2.22e-1)" "unprognostic (4.46e-2)" "unprognostic (6.50e-2)" "unprognostic (6.82e-2)" "prognostic unfavorable (1.23e-4)" "unprognostic (2.37e-1)" "unprognostic (7.27e-2)" "unprognostic (2.23e-1)" "unprognostic (2.84e-1)" "unprognostic (2.80e-1)" "unprognostic (6.50e-3)" 17.2 2.9 3.9 17.2 3.7 2.4 13.4 3.6 3.8 58.2 4.7 114.1 235.4 6.3 5.7 368.5 8.4 20.3 18.6 3.6 4.9 7.0 3.1 79.9 6.1 4.1 4.2 2.0 4.4 97.8 2.6 9.3 4.6 18.9 95.1 0.4 40.8 4.2 6.3 43.7 218.8 14.4 4.9 5.0 9.2 9.7 6.9 3.1 28.6 10.8 55.0 98.6 148.1 4.2 267.4 269.9 0.2 0.9 0.1 0.1 0.8 48.5 2.1 0.2 0.2 44.3 347.7 0.6 127.6 380.9 0.1 276.4 0.0 12.6 0.1 0.7 0.2 1.8 7.3 0.1 1.9 0.1 0.6 4.8 13.9 1.2 0.0 0.0 111.9 0.0 0.1 0.4 0.0 10.0 0.0 1.0 0.2 117.8 158.3 0.1 0.1 1.2 30.4 15.3 0.7 0.2 0.2 9.3 0.7 0.4 0.3 1.4 130.9 0.4 0.9 0.7 0.8 0.3 0.4 31.7 0.4 0.4 0.2 8.4 0.4 0.6 0.2 0.2 0.2 0.5 0.5 0.4 0.2 0.5 0.3 0.5 2.5 1.2 0.1 0.4 0.3 0.3 3.9 3.7 3.6 3.8 3.6 4.9 4.1 4.2 4.6 4.9 6.9 4.2 45.1 41.7 185.9 0.3 2.0 16.4 107.2 38.6 3.4 0.0 10.9 6.1 3.2 2.8 64.6 1.8 0.0 0.3 0.4 857.8 0.0 299.2 26.3 3.2 1.8 50.6 17.5 0.0 0.8 66.1 0.1 8.2 2.6 7.6 7.0 0.4 33.9 0.5 8.2 0.0 0.1 51.2 30.5 0.9 3.8 9.7 2.5 2.9 14.2 2.8 1.0 0.1 0.0 0.0 0.0 354.9 374.4 1.2 0.0 187.4 742.2 14.6 19.4 0.1 0.0 1.1 5.6 27.2 1.3 57.9 13.2 0.5 2.4 0.6 97.4 426.0 MAP1LC3B ATG8F ENSG00000140941 "Microtubule associated protein 1 light chain 3 beta" Q9GZQ8 16 87383953-87404779 "Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037216, HPA042824, HPA052474, HPA052484, HPA053767" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Vesicles Nucleoplasm "CAB037216: AB_796155, HPA042824: , HPA052474: AB_2681844, HPA052484: AB_2681846, HPA053767: AB_2682253" "unprognostic (4.70e-3)" "unprognostic (2.89e-1)" "unprognostic (3.21e-1)" "unprognostic (9.70e-3)" "unprognostic (4.28e-1)" "unprognostic (1.79e-2)" "unprognostic (4.98e-3)" "unprognostic (2.50e-2)" "unprognostic (1.20e-1)" "unprognostic (7.26e-2)" "unprognostic (1.04e-1)" "unprognostic (1.70e-1)" "prognostic favorable (2.77e-7)" "prognostic unfavorable (8.97e-4)" "unprognostic (9.66e-2)" "unprognostic (1.14e-1)" "unprognostic (1.60e-1)" 92.0 82.9 108.4 37.5 112.9 245.6 72.9 123.7 135.3 46.1 110.7 46.2 25.5 52.6 44.7 45.0 48.2 57.0 102.7 105.2 130.1 71.3 50.3 50.9 52.5 131.5 132.0 43.3 37.1 74.2 51.1 75.6 140.8 43.6 47.1 125.9 49.2 49.3 195.2 62.5 36.9 66.6 120.5 44.4 42.3 51.8 126.5 54.9 63.5 176.7 51.4 57.3 42.0 123.8 56.9 33.7 63.8 59.2 188.5 145.3 41.9 111.4 130.1 88.0 59.9 56.0 42.4 37.7 82.0 155.7 97.5 50.8 95.2 72.3 125.3 49.9 81.0 39.4 40.2 94.4 313.4 28.3 40.0 194.9 234.8 137.0 326.0 131.1 101.1 57.2 107.4 79.0 150.4 61.5 48.4 64.0 66.1 27.7 81.2 76.2 42.2 37.6 119.0 28.4 53.0 60.3 174.8 29.4 230.8 85.2 48.0 34.0 134.1 94.7 59.7 86.4 65.3 99.4 131.5 137.7 133.9 68.3 69.6 312.5 86.8 198.1 78.6 81.6 80.5 72.5 75.8 81.1 69.2 58.2 58.4 62.0 214.3 104.7 85.3 75.1 108.2 109.2 108.4 112.9 123.7 135.3 105.2 130.1 131.5 132.0 140.8 120.5 126.5 123.8 523.1 89.8 90.5 15.7 185.3 221.0 203.1 176.2 301.7 70.4 183.9 227.3 180.7 72.9 117.2 77.3 52.1 130.6 242.7 309.1 262.2 310.9 222.1 283.6 235.9 191.7 132.2 364.2 29.2 134.8 140.2 177.7 96.4 530.5 131.1 49.3 80.7 70.1 206.4 87.5 41.4 137.3 238.0 150.9 268.5 269.7 90.7 262.2 188.5 19.7 207.0 194.3 143.2 14.6 26.9 322.8 407.6 89.1 202.0 209.3 217.4 236.9 133.5 124.0 59.2 129.5 168.2 361.2 206.7 221.8 213.5 631.5 221.6 85.7 122.4 294.5 MAP4K4 "FLH21957, HGK, NIK" ENSG00000071054 "Mitogen-activated protein kinase kinase kinase kinase 4" O95819 2 101696850-101894689 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 472.1" "Cell type enhanced" "Detected in many" "Microglial cells: 337.3;Oligodendrocytes: 1134.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008476 Uncertain NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA008476: AB_1079362" "unprognostic (6.40e-2)" "unprognostic (1.09e-2)" "unprognostic (4.01e-1)" "unprognostic (1.89e-1)" "unprognostic (1.88e-1)" "unprognostic (1.87e-2)" "unprognostic (2.83e-2)" "prognostic unfavorable (1.57e-4)" "unprognostic (4.29e-2)" "unprognostic (9.79e-2)" "unprognostic (2.22e-3)" "unprognostic (8.65e-2)" "prognostic unfavorable (3.62e-6)" "unprognostic (6.67e-3)" "unprognostic (8.98e-2)" "unprognostic (3.15e-1)" "unprognostic (7.14e-3)" 54.1 9.1 272.6 42.9 316.1 72.5 32.2 208.8 252.5 23.9 95.0 21.1 10.6 27.4 12.1 35.2 19.7 34.5 44.8 219.4 256.3 15.0 32.8 29.2 54.1 317.5 286.1 23.1 16.1 15.0 10.0 49.4 273.1 13.9 17.8 22.7 19.3 10.2 37.4 21.1 17.7 28.7 246.7 24.2 22.0 40.1 348.5 44.3 15.8 30.6 60.1 33.1 25.6 472.1 112.7 83.8 175.2 84.3 162.4 288.6 219.5 139.8 114.3 122.2 100.1 139.5 145.6 163.1 118.3 210.3 36.0 45.5 56.0 123.2 121.1 219.8 38.0 122.4 62.5 367.7 136.7 59.1 5.5 261.3 55.3 301.9 133.5 122.1 322.5 90.3 80.9 0.4 325.4 61.3 137.8 36.5 89.2 42.5 131.5 164.1 120.0 0.6 81.2 38.8 68.5 113.6 96.5 0.4 104.0 160.8 22.4 105.1 409.1 240.5 102.9 70.6 168.6 0.3 0.4 96.7 155.2 73.2 180.1 8.8 3.2 0.0 2.3 3.2 1.6 3.4 2.9 1.5 1.1 5.0 2.2 2.5 13.5 1.1 3.1 6.0 3.7 1.5 272.6 316.1 208.8 252.5 219.4 256.3 317.5 286.1 273.1 246.7 348.5 472.1 104.3 19.2 23.9 283.0 64.5 30.0 41.9 17.4 12.5 109.1 14.3 17.4 71.0 28.6 29.6 18.4 50.1 13.1 38.4 12.0 0.0 57.4 31.5 67.2 77.1 84.2 17.4 48.0 197.5 53.2 23.4 49.7 26.5 101.0 24.0 151.8 67.1 39.2 38.8 35.3 122.4 13.6 14.2 26.9 245.9 46.0 55.0 54.7 19.6 337.3 88.0 49.2 10.3 228.7 1134.5 128.1 12.0 17.3 18.0 72.1 5.3 6.3 22.9 10.4 52.6 65.2 73.3 29.0 82.1 24.3 24.6 7.8 38.4 17.2 14.4 40.4 MCF2L "ARHGEF14, DBS, KIAA0362, OST" ENSG00000126217 "MCF.2 cell line derived transforming sequence like" O15068 13 112894378-113099742 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 134.5" "Cell type enhanced" "Detected in many" "Adipocytes: 138.3;Bipolar cells: 70.4;Cone photoreceptor cells: 127.2;Endothelial cells: 69.7;Microglial cells: 92.8;Oligodendrocytes: 75.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 35.9;SCLC-21H: 65.3;SH-SY5Y: 29.0;SK-BR-3: 43.9;WM-115: 60.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.56e-1)" "unprognostic (2.53e-2)" "unprognostic (8.86e-3)" "prognostic favorable (6.01e-4)" "unprognostic (9.07e-2)" "unprognostic (3.91e-2)" "unprognostic (7.07e-2)" "unprognostic (3.02e-2)" "unprognostic (1.94e-1)" "unprognostic (2.11e-1)" "prognostic favorable (4.36e-5)" "unprognostic (1.17e-1)" "prognostic favorable (9.14e-6)" "unprognostic (2.04e-2)" "unprognostic (1.28e-1)" "unprognostic (2.24e-1)" "prognostic favorable (2.63e-5)" 44.1 7.6 39.0 6.3 35.1 0.9 39.5 134.5 76.1 16.5 0.4 17.5 11.3 19.4 5.1 14.1 17.8 13.4 52.8 32.3 27.7 17.5 7.7 19.0 6.8 51.3 40.6 4.8 18.8 10.3 44.4 8.4 57.6 17.0 13.7 20.0 32.7 8.5 16.5 24.8 18.7 7.1 29.1 3.6 18.1 2.0 49.3 7.1 27.6 16.3 6.0 15.0 16.9 47.7 0.0 1.6 14.9 4.8 0.5 0.9 2.1 0.0 0.0 0.0 0.0 3.8 2.2 0.1 3.7 1.5 2.5 0.3 3.8 0.0 0.0 0.0 7.4 4.3 0.2 9.1 0.5 0.2 3.1 1.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.2 14.4 5.6 0.5 2.6 4.0 35.9 0.0 0.2 15.0 7.9 5.9 23.6 65.3 29.0 0.0 43.9 0.1 2.4 26.0 0.1 0.6 0.1 12.5 5.4 0.0 7.5 0.4 2.3 23.9 1.0 60.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.4 0.1 0.3 0.0 0.0 0.0 0.0 0.4 39.0 35.1 134.5 76.1 32.3 27.7 51.3 40.6 57.6 29.1 49.3 47.7 138.3 0.0 8.4 4.6 2.6 5.5 3.4 1.5 8.0 70.4 12.9 10.0 44.3 12.8 4.6 9.2 127.2 0.0 1.2 10.8 7.9 5.6 0.4 9.9 1.6 69.7 26.5 0.0 58.5 2.6 0.2 7.1 23.0 18.7 1.3 11.2 13.6 3.4 1.4 38.7 60.9 54.6 8.2 2.2 4.6 1.5 0.6 2.5 8.8 92.8 0.1 5.4 0.0 40.7 75.0 1.7 9.8 1.2 3.0 4.2 4.0 10.4 7.2 23.9 0.0 5.2 11.9 0.7 2.7 4.2 9.1 0.1 2.1 0.5 7.4 4.1 MEF2C ENSG00000081189 "Myocyte enhancer factor 2C" Q06413 5 88717117-88904257 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 555.4;tongue: 246.8" "Cell type enhanced" "Detected in many" "B-cells: 471.5;Excitatory neurons: 735.7;Inhibitory neurons: 759.5;Microglial cells: 730.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "amygdala: 29.7;basal ganglia: 58.6;cerebral cortex: 75.3;hippocampal formation: 55.7" "Group enriched" "Detected in many" 4 "classical monocyte: 72.0;intermediate monocyte: 82.6;memory B-cell: 141.6;myeloid DC: 95.2;naive B-cell: 187.9;non-classical monocyte: 71.5;plasmacytoid DC: 100.3" "Group enriched" "Detected in many" 5 "B-cells: 187.9;dendritic cells: 100.3;monocytes: 82.6" "Cell line enhanced" "Detected in many" "Daudi: 103.6;HEL: 229.3;Karpas-707: 121.6;REH: 261.8;WM-115: 145.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 70.0;cerebral cortex: 253.1;hippocampal formation: 220.0;olfactory bulb: 66.8" "HPA005533, CAB068196, CAB068197" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Vesicles" "CAB068196: AB_2665646, CAB068197: AB_2665645, HPA005533: AB_1079352" "unprognostic (2.74e-1)" "unprognostic (1.64e-2)" "unprognostic (2.37e-2)" "unprognostic (8.78e-2)" "unprognostic (9.75e-2)" "unprognostic (1.69e-1)" "unprognostic (1.06e-1)" "unprognostic (3.19e-2)" "unprognostic (3.52e-2)" "unprognostic (8.73e-2)" "unprognostic (1.15e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (7.18e-3)" "unprognostic (1.58e-1)" "unprognostic (4.42e-2)" "unprognostic (1.42e-2)" 28.9 26.8 29.7 39.2 58.6 11.1 17.5 0.0 75.3 18.8 0.0 15.9 6.9 25.9 7.3 13.6 17.3 28.5 35.2 55.7 0.0 10.4 10.5 21.3 62.9 0.0 0.0 34.9 5.6 9.3 6.3 45.5 0.0 20.0 15.4 34.2 9.0 17.7 555.4 4.9 11.2 31.5 0.0 43.8 12.7 9.4 0.0 12.8 21.7 246.8 77.7 21.3 7.6 11.0 1.6 0.0 7.1 0.0 7.7 4.6 0.2 2.2 4.5 0.3 1.0 0.2 1.0 103.6 0.6 12.0 2.5 3.1 9.6 9.1 0.2 31.7 12.5 229.3 12.3 0.0 2.8 10.4 0.6 21.6 0.0 0.3 0.0 1.4 35.1 0.0 12.3 121.6 9.0 0.0 0.3 0.1 2.2 0.1 8.4 261.8 63.1 50.5 0.0 1.2 0.0 8.3 0.0 0.7 29.5 3.9 0.3 58.0 40.4 5.6 1.0 0.6 5.4 92.0 11.5 62.0 1.5 70.1 145.2 0.6 72.0 0.2 0.2 82.6 0.1 141.6 0.2 0.1 95.2 187.9 0.2 0.2 24.3 16.7 71.5 100.3 0.5 34.4 29.7 58.6 0.0 75.3 55.7 0.0 0.0 0.0 0.0 0.0 0.0 11.0 367.4 32.1 52.0 117.5 471.5 10.7 4.2 0.0 7.4 22.6 5.2 26.5 86.4 10.0 21.7 1.8 214.8 0.8 138.6 9.2 27.4 0.8 11.0 0.8 13.4 197.5 1.2 59.1 735.7 12.7 1.2 26.8 2.0 1.0 5.1 107.5 283.4 3.4 171.1 5.0 759.5 1.5 0.0 205.8 127.5 8.6 29.8 205.1 67.6 730.7 202.7 61.8 8.2 119.6 18.7 0.4 3.0 71.8 314.7 2.1 0.2 0.8 3.7 202.9 335.2 72.7 257.6 4.0 29.5 2.5 8.4 1.6 12.2 58.6 6.3 2.3 MID1 "FXY, OS, RNF59, TRIM18" ENSG00000101871 "Midline 1" O15344 X 10445310-10833654 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 129.3;Basal squamous epithelial cells: 82.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 156.1;AF22: 132.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002878, HPA003715" Approved Uncertain "Golgi apparatus,Centriolar satellite,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Centriolar satellite" "Golgi apparatus, Cytosol" "HPA002878: , HPA003715: AB_1079384" "unprognostic (1.99e-1)" "unprognostic (2.81e-1)" "unprognostic (4.66e-2)" "unprognostic (2.79e-1)" "unprognostic (2.78e-1)" "unprognostic (2.61e-1)" "prognostic unfavorable (3.06e-4)" "unprognostic (1.19e-1)" "unprognostic (3.61e-1)" "unprognostic (2.09e-1)" "unprognostic (2.87e-1)" "unprognostic (9.43e-2)" "unprognostic (1.25e-3)" "unprognostic (9.89e-2)" "unprognostic (1.49e-1)" "unprognostic (1.12e-3)" "unprognostic (5.88e-2)" 5.9 2.5 6.9 5.0 7.7 1.7 5.3 17.2 5.0 7.0 6.5 17.3 5.7 8.9 4.9 7.0 6.4 6.8 9.3 7.0 4.9 7.3 4.2 6.5 2.2 3.6 10.4 4.4 3.5 2.8 4.2 6.2 4.9 10.4 10.6 12.3 4.9 12.9 0.7 2.9 5.8 12.3 2.1 1.0 3.8 3.6 8.2 2.3 4.2 2.2 3.1 11.7 6.2 4.4 33.2 156.1 132.5 16.7 8.1 9.2 14.6 16.2 17.8 19.7 20.7 31.0 9.7 10.6 6.5 21.9 58.4 22.5 11.0 15.1 23.0 1.3 11.0 2.7 24.3 1.1 2.8 0.3 1.2 12.1 7.0 16.1 15.8 20.4 23.1 5.1 2.1 3.2 9.6 8.0 5.3 0.5 32.7 5.1 10.0 3.9 28.9 0.4 18.7 36.2 7.1 3.5 7.4 23.5 10.1 42.7 19.2 0.2 13.7 7.2 1.0 34.1 17.0 2.8 1.2 0.4 13.5 0.3 31.3 0.5 0.1 0.6 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.3 0.0 0.1 0.7 0.0 0.1 0.4 0.0 0.1 6.9 7.7 17.2 5.0 7.0 4.9 3.6 10.4 4.9 2.1 8.2 4.4 16.5 35.3 20.7 129.3 0.7 21.4 31.5 24.7 82.6 10.7 8.5 13.2 4.8 8.6 19.6 23.9 18.8 9.1 1.3 22.6 1.9 13.4 2.2 39.8 8.9 25.4 12.1 2.7 15.5 8.7 26.9 16.2 10.7 38.5 1.3 13.4 69.9 4.0 1.5 69.0 44.3 9.0 2.0 2.5 5.8 7.9 30.1 1.2 3.6 23.4 0.0 37.0 0.0 66.4 59.2 7.3 17.2 41.3 0.2 8.2 11.3 1.5 19.3 2.9 6.6 3.7 3.3 0.3 2.4 36.1 10.1 20.0 0.8 9.7 20.0 49.2 MMRN2 "EMILIN3, EndoGlyx-1, FLJ13465" ENSG00000173269 "Multimerin 2" Q9H8L6 10 86935540-86969481 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 11 "Adipocytes: 229.3;Endothelial cells: 127.1;Hepatic stellate cells: 182.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 89.2;HUVEC TERT2: 196.6;TIME: 237.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020741 Approved Vesicles "Secreted to extracellular matrix" NA NA 84000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA020741: AB_1848154" "unprognostic (4.17e-1)" "unprognostic (7.87e-2)" "unprognostic (6.67e-3)" "unprognostic (3.30e-1)" "unprognostic (1.73e-1)" "unprognostic (2.08e-2)" "unprognostic (1.75e-3)" "unprognostic (1.43e-1)" "unprognostic (2.09e-2)" "unprognostic (3.11e-2)" "unprognostic (1.81e-2)" "unprognostic (1.34e-1)" "unprognostic (6.17e-3)" "unprognostic (1.54e-3)" "unprognostic (1.25e-1)" "unprognostic (6.44e-2)" "unprognostic (1.66e-1)" 63.2 13.9 14.0 10.1 12.7 1.5 54.5 11.5 12.5 20.6 11.0 14.2 10.5 28.1 13.8 16.9 22.7 16.6 38.8 11.4 11.9 22.0 8.6 32.1 9.7 13.6 12.4 23.1 10.5 10.6 7.6 73.8 13.7 14.1 8.9 3.0 26.6 28.7 26.8 38.9 13.8 27.3 13.2 34.6 11.9 15.3 15.8 6.5 25.8 32.5 13.3 32.3 19.1 12.0 11.4 2.9 0.4 0.2 1.2 6.3 7.1 4.1 11.1 4.8 6.8 6.4 89.2 0.1 39.5 7.6 11.6 21.9 0.0 5.2 6.4 8.1 0.0 2.3 10.2 0.2 0.9 0.0 4.6 1.5 26.4 5.7 38.6 13.0 196.6 2.4 2.1 35.0 1.8 7.1 0.4 4.4 2.0 0.4 4.9 0.2 0.1 0.1 2.0 17.5 4.8 0.0 3.1 3.7 1.4 0.9 14.9 1.2 237.1 1.9 11.0 1.9 0.1 2.6 4.0 0.1 5.8 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 14.0 12.7 11.5 12.5 11.4 11.9 13.6 12.4 13.7 13.2 15.8 12.0 229.3 0.0 5.8 1.6 0.3 9.4 0.9 0.0 4.6 0.2 1.4 2.0 13.2 5.7 0.7 1.8 0.0 0.7 0.4 0.0 0.0 0.1 1.0 0.3 0.4 127.1 0.0 2.7 0.9 0.0 0.1 8.1 0.0 0.5 0.0 0.2 182.0 4.1 1.7 0.0 1.2 0.0 0.0 6.5 4.4 2.8 2.5 0.7 3.6 15.9 0.0 0.7 0.0 1.0 0.1 0.0 0.0 3.0 0.1 0.6 0.5 0.2 0.0 0.6 6.6 3.9 9.4 1.8 2.3 2.2 7.7 0.3 0.8 3.6 0.2 1.0 MPZL2 "EVA, EVA1" ENSG00000149573 "Myelin protein zero like 2" O60487 11 118253416-118264536 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 222.5;urinary bladder: 155.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 332.5;Basal prostatic cells: 504.4;Basal respiratory cells: 289.1;Squamous epithelial cells: 336.4;Suprabasal keratinocytes: 467.4;Urothelial cells: 489.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 11.6;intermediate monocyte: 9.2;myeloid DC: 17.0;neutrophil: 13.2" "Group enriched" "Detected in many" 10 "dendritic cells: 17.0;granulocytes: 13.2;monocytes: 11.6" "Cell line enhanced" "Detected in some" "CAPAN-2: 120.9;EFO-21: 130.4;HaCaT: 166.9;RT4: 321.7;TIME: 351.9" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "spinal cord: 38.8" HPA060740 Approved Approved "Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "HPA060740: AB_2684352" "unprognostic (1.74e-1)" "unprognostic (6.02e-2)" "unprognostic (8.23e-2)" "unprognostic (3.28e-3)" "unprognostic (9.95e-3)" "unprognostic (1.56e-1)" "unprognostic (2.11e-3)" "unprognostic (3.58e-1)" "unprognostic (7.39e-2)" "unprognostic (5.45e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.91e-1)" "unprognostic (3.91e-2)" "unprognostic (3.07e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.62e-4)" "unprognostic (2.08e-2)" 28.6 4.7 2.5 11.9 2.1 0.7 19.6 2.3 4.8 56.7 5.2 31.1 17.0 16.9 38.5 222.5 46.4 33.5 7.2 2.3 2.6 26.4 23.2 47.0 2.3 3.2 3.0 3.8 13.5 27.1 10.7 1.7 3.2 48.6 30.8 0.9 58.0 69.5 4.7 38.8 11.3 14.7 3.6 4.6 37.0 0.9 3.4 18.1 30.3 1.0 52.6 155.9 120.5 2.8 65.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 27.0 120.9 0.3 130.4 0.0 0.6 166.9 0.0 38.9 0.0 0.2 9.5 0.1 1.7 35.8 0.0 0.0 0.4 0.0 90.2 0.0 3.0 0.0 86.8 0.8 0.0 0.2 0.0 51.3 0.2 0.2 1.6 34.2 0.1 0.0 0.0 6.4 14.9 321.7 0.1 0.0 5.8 61.4 0.0 0.5 26.1 0.7 351.9 0.1 0.2 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.0 2.3 11.6 3.0 0.1 9.2 1.3 0.0 0.6 0.4 17.0 0.0 0.8 0.9 13.2 0.4 1.4 0.3 0.2 3.8 2.5 2.1 2.3 4.8 2.3 2.6 3.2 3.0 3.2 3.6 3.4 2.8 5.9 83.3 123.3 0.0 0.2 332.5 504.4 289.1 127.5 0.0 29.0 17.4 3.4 30.0 221.1 128.8 0.0 1.7 0.5 52.0 0.0 39.4 0.0 91.6 18.8 33.6 5.3 3.6 0.0 51.1 0.2 8.2 29.6 194.0 7.0 0.0 45.3 16.5 0.8 0.0 0.0 6.3 81.4 6.4 27.0 0.3 0.0 7.8 21.4 1.9 4.9 0.0 1.0 0.0 0.0 68.2 20.8 0.0 1.2 186.3 3.3 6.9 65.2 0.0 0.0 0.3 9.2 0.2 0.7 336.4 467.4 17.8 5.4 0.0 33.4 489.7 MSX1 "HOX7, HYD1, OFC5" ENSG00000163132 "Msh homeobox 1" P28360 4 4859665-4863936 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 57.0;choroid plexus: 98.0" "Group enriched" "Detected in many" 6 "Adipocytes: 118.4;Endometrial ciliated cells: 364.0;Glandular and luminal cells: 462.0" "Cancer enriched" "Detected in all" 17 "endometrial cancer: 246.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 47.9;EFO-21: 21.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB026198, HPA063895, HPA073604" Enhanced Supported Nucleoplasm NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB026198: , HPA063895: AB_2685145, HPA073604: AB_2686617" "unprognostic (1.12e-1)" "unprognostic (1.93e-2)" "unprognostic (3.39e-2)" "prognostic favorable (1.64e-7)" "unprognostic (9.13e-2)" "unprognostic (1.16e-3)" "unprognostic (4.07e-3)" "unprognostic (3.81e-2)" "unprognostic (1.48e-2)" "unprognostic (2.21e-3)" "unprognostic (4.78e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (1.18e-5)" "unprognostic (4.35e-2)" "unprognostic (2.06e-1)" "unprognostic (2.34e-3)" "unprognostic (1.33e-2)" 18.4 6.0 12.2 0.7 11.8 0.2 12.8 12.2 16.9 57.0 98.0 1.8 0.5 17.5 0.3 0.9 9.6 1.3 10.3 18.8 12.2 2.9 0.5 4.3 0.6 17.2 11.8 3.5 2.3 0.4 21.1 4.1 11.8 5.5 0.1 0.6 8.8 3.6 20.1 5.2 1.1 3.2 15.1 4.5 2.0 0.7 13.0 0.2 9.2 2.0 0.4 11.2 14.5 12.3 2.5 1.5 0.5 2.8 8.0 5.1 8.9 6.1 2.8 3.5 1.7 47.9 15.3 0.3 21.4 4.4 17.0 0.1 10.6 0.0 1.2 2.0 12.2 0.1 8.0 17.4 0.6 0.1 1.4 1.0 0.8 2.6 0.9 1.1 0.8 4.1 7.9 0.3 1.9 1.2 1.3 2.4 0.2 0.7 11.1 6.4 6.4 0.6 0.2 1.5 0.4 0.3 5.4 0.3 4.0 0.8 0.9 2.1 2.0 4.1 9.1 13.0 9.9 1.0 0.9 5.7 2.6 3.1 4.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 12.2 11.8 12.2 16.9 18.8 12.2 17.2 11.8 11.8 15.1 13.0 12.3 118.4 0.0 0.0 17.3 0.5 7.1 2.4 0.3 4.6 0.8 8.6 24.3 5.5 0.0 0.0 0.0 4.2 0.3 1.6 3.9 0.0 0.2 0.4 364.0 35.7 48.1 0.0 0.0 1.1 0.9 0.1 34.8 1.1 462.0 0.0 1.1 5.7 0.2 0.5 0.0 1.2 2.5 0.0 0.6 8.8 0.0 1.2 4.4 16.0 3.7 0.0 0.7 0.0 1.0 0.3 0.3 0.1 0.4 1.6 3.3 0.6 0.5 0.0 0.7 0.0 13.6 18.2 0.8 1.5 2.6 4.7 0.3 4.8 14.6 2.6 2.0 MTSS1 "KIAA0429, MIM, MIMA, MIMB" ENSG00000170873 "MTSS I-BAR domain containing 1" O43312 8 124550784-124728473 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 208.2;Oligodendrocyte precursor cells: 360.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 168.3" "Group enriched" "Detected in all" 5 "B-cells: 50.3;monocytes: 168.3" "Cell line enhanced" "Detected in many" "ASC diff: 81.4;HDLM-2: 98.7;HEL: 337.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019613, HPA064003, HPA075540" Approved Supported Approved "Plasma membrane,Cytosol" NA NA 140000 "Cluster 51: Monocytes - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "HPA019613: , HPA064003: , HPA075540: AB_2686756" "unprognostic (1.70e-1)" "unprognostic (4.13e-2)" "unprognostic (9.50e-2)" "unprognostic (1.38e-1)" "unprognostic (3.87e-2)" "unprognostic (7.02e-2)" "unprognostic (4.24e-2)" "unprognostic (1.26e-2)" "unprognostic (2.18e-1)" "unprognostic (2.50e-1)" "unprognostic (8.12e-2)" "unprognostic (1.48e-1)" "prognostic favorable (2.11e-7)" "unprognostic (6.74e-2)" "unprognostic (1.04e-1)" "unprognostic (2.41e-1)" "unprognostic (8.92e-3)" 24.5 36.2 16.8 13.2 23.2 12.5 14.0 46.1 23.4 12.5 22.3 11.0 6.4 8.4 9.9 45.2 12.5 9.2 17.1 16.3 27.7 24.2 72.9 16.5 16.0 27.5 20.6 10.4 28.5 3.7 11.0 35.7 25.3 10.1 9.1 15.0 13.9 6.3 32.3 30.8 7.9 9.6 20.5 34.5 12.0 22.3 26.4 18.4 6.0 24.4 17.2 15.5 24.3 39.5 3.6 1.1 51.6 1.0 81.4 41.7 0.1 2.1 14.2 1.1 0.5 4.8 0.4 1.6 4.9 0.2 0.4 0.8 0.4 29.2 1.1 98.7 1.2 337.8 0.9 27.0 18.4 0.0 34.5 66.4 65.4 15.9 41.0 2.1 31.5 0.3 0.5 0.3 5.6 2.7 0.8 4.0 1.8 54.8 0.4 0.4 0.1 0.5 11.6 11.3 36.3 2.8 7.9 6.3 26.6 2.5 1.3 1.1 16.7 2.7 1.0 0.2 0.7 0.5 0.3 5.4 29.1 0.4 10.7 3.1 13.1 0.1 22.7 88.1 2.6 44.9 4.8 8.7 11.8 50.3 2.2 6.8 2.2 2.2 168.3 0.2 0.5 29.2 16.8 23.2 46.1 23.4 16.3 27.7 27.5 20.6 25.3 20.5 26.4 39.5 33.0 0.0 26.9 15.7 92.0 35.8 81.4 41.2 9.6 0.0 8.0 19.9 34.9 22.8 30.9 66.2 0.0 36.0 51.4 10.7 21.5 17.6 54.2 25.5 0.9 32.2 44.2 17.2 40.4 5.2 2.3 30.5 26.5 9.7 46.3 0.9 70.3 78.1 74.2 0.0 208.2 17.1 61.1 167.1 116.2 62.1 3.7 96.7 26.6 114.3 90.2 0.0 78.2 360.4 178.4 32.6 15.9 4.5 12.6 71.9 1.2 19.9 42.0 0.0 39.5 25.2 17.3 2.5 10.7 86.1 63.4 94.4 22.7 1.8 15.8 59.2 NAV1 "DKFZp781D0314, FLJ12560, FLJ14203, KIAA1151, MGC14961, POMFIL3, steerin-1" ENSG00000134369 "Neuron navigator 1" Q8NEY1 1 201622885-201826969 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 169.1;Inhibitory neurons: 161.7;Oligodendrocyte precursor cells: 713.8;Oligodendrocytes: 224.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.4;myeloid DC: 2.1" "Group enriched" "Detected in many" 5 "dendritic cells: 2.1;granulocytes: 3.4" "Cell line enhanced" "Detected in many" "TIME: 187.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012302, HPA018127, HPA027887" Enhanced Approved Microtubules NA NA "Cluster 46: Basophils - DNA binding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" Microtubules "CAB012302: AB_776716, HPA018127: AB_1854317, HPA027887: AB_10601040" "unprognostic (2.14e-1)" "unprognostic (1.82e-1)" "unprognostic (4.12e-2)" "unprognostic (3.33e-2)" "unprognostic (1.14e-1)" "unprognostic (3.87e-1)" "unprognostic (1.79e-1)" "unprognostic (3.45e-1)" "unprognostic (9.10e-2)" "unprognostic (5.63e-2)" "unprognostic (4.68e-1)" "unprognostic (8.24e-2)" "prognostic unfavorable (3.10e-6)" "unprognostic (3.45e-2)" "unprognostic (2.16e-1)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" 19.6 2.7 17.4 8.2 18.3 1.6 15.2 8.0 17.7 11.7 0.0 12.3 3.7 10.1 4.3 8.6 7.2 7.5 26.6 17.5 20.3 4.6 1.9 11.1 4.1 24.6 17.9 3.7 4.4 5.2 5.2 11.8 15.1 7.5 5.4 5.4 7.8 6.7 4.8 7.7 6.2 10.3 9.9 3.6 5.3 4.4 21.8 2.8 9.4 6.7 3.7 14.9 12.6 32.5 1.6 2.9 29.0 3.8 84.3 69.5 51.7 44.6 43.0 35.5 30.9 0.0 15.7 0.6 0.7 61.4 19.4 21.5 22.0 14.9 28.4 2.5 3.2 1.4 5.6 0.0 22.5 0.2 19.1 30.6 5.4 62.4 36.0 94.9 80.7 1.8 0.8 2.6 29.8 0.4 0.0 0.1 42.4 0.7 1.7 3.9 65.0 9.3 4.8 4.3 21.9 4.5 11.1 47.6 14.5 19.2 0.4 1.2 187.8 54.5 11.1 54.7 39.4 8.1 2.3 0.2 59.2 5.9 47.5 3.4 0.5 0.1 0.2 0.3 0.1 0.3 0.2 0.0 2.1 0.3 0.2 0.1 0.0 0.1 0.3 0.5 0.0 0.3 17.4 18.3 8.0 17.7 17.5 20.3 24.6 17.9 15.1 9.9 21.8 32.5 77.4 3.2 1.5 169.1 3.1 11.0 2.2 5.9 8.0 34.6 4.8 4.3 29.2 1.5 4.8 12.9 0.0 14.9 0.9 4.7 0.0 13.0 3.6 1.6 6.4 39.3 52.8 1.7 98.2 8.3 54.1 45.8 8.2 4.4 17.7 54.5 21.0 0.7 14.5 25.2 161.7 3.4 6.1 18.3 15.8 3.8 10.8 15.1 23.2 69.3 60.6 11.8 1.0 713.8 224.6 21.7 4.2 0.7 4.9 2.3 0.9 0.6 3.5 4.0 6.6 119.3 18.8 0.6 2.6 16.9 7.0 15.7 2.0 6.6 5.0 3.2 NCOA7 "dJ187J11.3, ERAP140, TLDC4" ENSG00000111912 "Nuclear receptor coactivator 7" Q8NI08 6 125781161-125932034 "Predicted intracellular proteins, Transporters" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 709.7;Squamous epithelial cells: 515.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030289, HPA030290, HPA030291, HPA030292" Approved Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nuclear bodies" "Golgi apparatus" "HPA030289: AB_10670031, HPA030290: AB_10601971, HPA030291: AB_10669597, HPA030292: AB_10670834" "unprognostic (1.01e-2)" "unprognostic (3.21e-2)" "unprognostic (7.32e-3)" "unprognostic (7.27e-3)" "unprognostic (1.54e-1)" "unprognostic (4.67e-2)" "unprognostic (1.26e-1)" "unprognostic (6.27e-2)" "unprognostic (2.73e-1)" "unprognostic (2.14e-1)" "unprognostic (6.08e-2)" "unprognostic (4.37e-2)" "prognostic favorable (1.78e-6)" "unprognostic (2.10e-1)" "unprognostic (2.58e-1)" "unprognostic (1.14e-1)" "unprognostic (8.10e-2)" 53.9 60.4 19.5 45.8 30.6 42.7 27.4 21.4 50.2 29.0 0.0 30.1 33.0 22.3 5.2 30.4 15.9 46.6 16.0 28.2 23.9 56.6 32.9 52.1 30.1 47.5 12.3 14.8 19.9 8.8 29.7 12.9 45.0 18.6 29.2 18.2 38.2 12.9 6.9 11.1 39.2 28.3 10.6 24.4 30.8 7.8 19.0 21.7 25.1 9.2 28.5 101.8 19.7 48.3 13.7 36.6 2.2 16.0 78.2 46.3 23.7 18.2 71.9 22.1 30.1 34.3 12.7 55.2 96.5 10.0 108.0 78.7 12.6 12.4 13.3 120.2 16.5 28.0 43.7 12.3 44.5 16.4 25.4 33.3 29.4 21.1 16.3 39.1 46.7 18.0 38.7 30.6 13.9 13.7 16.1 16.2 2.7 33.8 7.6 12.3 5.7 10.3 39.1 90.4 36.9 33.5 93.7 22.6 42.1 6.5 3.8 19.3 27.7 5.1 10.9 26.3 14.1 39.9 34.1 28.8 11.5 21.2 18.7 17.0 11.4 4.0 19.2 9.1 24.1 17.7 18.1 15.6 10.0 11.1 9.6 9.4 6.4 13.6 14.2 34.1 8.1 5.1 19.5 30.6 21.4 50.2 28.2 23.9 47.5 12.3 45.0 10.6 19.0 48.3 144.6 314.1 371.9 27.7 33.7 98.1 270.8 311.2 709.7 50.2 94.2 47.9 11.4 98.7 324.1 62.5 43.8 9.3 84.6 113.2 80.3 241.7 0.9 160.1 90.2 130.2 35.8 29.8 144.9 139.2 8.9 94.8 142.8 298.2 37.3 18.5 106.7 23.2 13.6 37.0 89.5 119.3 288.9 33.8 57.4 6.8 42.3 41.9 51.6 75.9 33.4 76.8 59.8 34.2 303.9 108.7 160.1 29.3 44.1 129.5 24.3 103.2 335.8 53.3 13.1 33.8 49.3 11.2 33.9 515.9 59.2 3.8 63.5 36.5 130.6 294.4 NETO2 "FLJ10430, NEOT2" ENSG00000171208 "Neuropilin and tolloid like 2" Q8NC67 16 47077703-47143945 "Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.8;lymphoid tissue: 22.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 96.5;Inhibitory neurons: 176.6;Oligodendrocyte precursor cells: 79.4;Theca cells: 98.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013180 Uncertain Approved "Golgi apparatus" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA013180: AB_1854383" "unprognostic (2.67e-2)" "unprognostic (3.46e-2)" "unprognostic (3.90e-1)" "unprognostic (1.51e-3)" "unprognostic (2.25e-1)" "unprognostic (5.26e-3)" "unprognostic (1.10e-2)" "unprognostic (5.73e-2)" "unprognostic (1.92e-2)" "unprognostic (2.32e-1)" "unprognostic (1.26e-1)" "unprognostic (3.98e-1)" "prognostic unfavorable (5.53e-6)" "unprognostic (3.48e-2)" "unprognostic (1.66e-1)" "unprognostic (6.79e-2)" "unprognostic (1.32e-1)" 2.7 7.2 6.1 6.4 19.8 2.4 2.8 3.6 9.3 1.6 1.0 8.5 1.6 2.2 0.6 6.1 0.8 4.8 2.6 4.1 8.3 2.7 0.7 5.9 6.3 6.9 0.8 1.6 2.5 10.7 1.2 3.4 6.4 1.1 2.4 7.5 2.7 1.2 4.4 1.8 2.8 1.6 1.7 22.7 2.2 8.0 3.5 5.4 8.8 2.2 6.2 4.9 2.9 4.2 86.8 94.4 133.9 0.3 19.3 111.6 22.2 84.0 13.2 72.9 39.3 19.9 54.0 21.3 50.4 18.0 70.2 37.9 86.4 83.6 89.0 0.3 55.7 17.2 32.8 21.3 23.9 55.8 43.7 67.9 54.7 29.5 41.2 70.5 49.2 50.5 25.9 25.7 47.4 23.5 31.9 30.4 64.7 25.8 68.8 0.1 26.2 43.0 51.4 18.3 87.8 63.5 110.9 8.6 12.5 21.8 1.7 40.3 24.1 0.1 0.3 0.1 0.5 27.5 24.7 47.6 58.9 38.9 59.6 0.3 0.9 0.0 0.0 0.5 0.3 0.2 0.3 0.0 0.6 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.5 0.1 6.1 19.8 3.6 9.3 4.1 8.3 6.9 0.8 6.4 1.7 3.5 4.2 4.9 0.0 4.5 4.6 6.5 7.8 0.6 10.4 13.1 2.2 5.2 8.9 1.3 0.0 3.6 0.0 0.0 1.4 2.1 15.9 0.0 0.4 3.1 2.1 4.0 10.6 10.8 0.4 96.5 3.1 0.5 4.9 1.5 0.9 2.5 18.0 2.9 0.4 6.6 0.0 176.6 2.6 6.1 11.4 14.6 5.7 0.6 16.6 3.6 8.4 7.3 39.9 1.0 79.4 3.1 1.3 1.5 0.0 13.7 4.9 2.9 0.1 2.4 1.6 6.6 5.3 3.6 17.9 22.2 18.8 3.3 0.8 5.2 98.7 2.8 1.4 NOD1 "CARD4, CLR7.1, NLRC1" ENSG00000106100 "Nucleotide binding oligomerization domain containing 1" Q9Y239 7 30424527-30478784 "Human disease related genes, Predicted intracellular proteins" "Apoptosis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 19.3;Microglial cells: 26.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 11.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA074367 Approved Mitochondria NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Mitochondria "HPA074367: AB_2686683" "unprognostic (2.58e-1)" "unprognostic (1.56e-2)" "unprognostic (9.73e-2)" "unprognostic (8.09e-3)" "unprognostic (2.07e-2)" "unprognostic (1.70e-1)" "unprognostic (1.01e-3)" "unprognostic (6.63e-2)" "unprognostic (2.26e-1)" "unprognostic (2.74e-1)" "unprognostic (8.78e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (6.68e-4)" "unprognostic (6.62e-2)" "unprognostic (1.46e-1)" "prognostic favorable (1.95e-4)" "unprognostic (2.64e-1)" 10.6 2.9 3.0 8.8 3.2 6.8 9.5 2.5 2.6 5.3 4.6 5.3 2.2 6.1 2.6 4.7 6.5 5.4 7.3 2.4 3.2 3.9 2.2 11.9 6.1 7.6 4.9 10.3 1.8 2.7 2.9 12.2 4.7 4.0 4.3 0.6 6.2 3.2 4.0 5.9 5.4 7.3 3.6 11.1 4.8 1.9 5.6 3.5 10.8 4.0 5.0 7.3 5.0 2.8 4.8 2.5 3.5 10.5 2.2 10.3 5.3 3.3 2.3 5.5 7.0 2.2 5.7 6.9 3.8 4.2 6.1 11.2 3.5 5.8 3.7 3.6 3.0 9.7 7.7 2.2 2.8 4.3 7.0 9.6 2.5 3.5 3.0 4.9 18.3 10.1 5.2 2.4 5.0 2.8 6.2 7.7 4.1 5.3 4.5 7.4 4.0 6.3 1.8 3.8 0.6 12.4 4.2 10.7 3.7 4.8 3.6 9.6 7.7 4.8 7.6 6.0 4.5 2.2 8.0 0.3 3.5 15.1 5.1 13.7 3.7 13.5 8.1 5.0 8.9 7.5 5.5 5.3 3.3 10.9 4.9 4.0 2.8 8.5 6.6 8.0 4.8 2.6 3.0 3.2 2.5 2.6 2.4 3.2 7.6 4.9 4.7 3.6 5.6 2.8 19.3 3.2 15.1 7.2 6.6 0.8 0.5 1.0 5.2 2.4 2.9 2.9 4.9 1.5 5.0 5.5 0.0 5.0 6.7 4.5 0.0 1.3 0.2 4.4 1.7 12.0 0.0 3.4 5.3 2.1 2.3 8.2 1.1 4.6 2.5 7.8 13.6 1.3 4.6 0.0 1.4 5.5 2.0 3.1 3.7 0.0 0.6 4.3 5.4 26.2 4.0 0.6 6.2 2.5 1.1 1.7 1.7 1.9 3.1 0.2 1.6 0.5 2.9 0.2 0.0 2.5 5.6 0.0 0.6 5.4 1.8 1.5 5.3 1.0 5.6 0.8 NOTCH1 TAN1 ENSG00000148400 "Notch receptor 1" P46531 9 136494433-136546048 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Angiogenesis, Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 56.2;Astrocytes: 67.3;Hepatic stellate cells: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 47.0;HDLM-2: 32.3;HMC-1: 39.7;MOLT-4: 72.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008112, CAB022466, HPA067168" Supported Approved Nucleoplasm NA NA 29000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB008112: AB_2153490, CAB022466: , HPA067168: AB_2685795" "unprognostic (1.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.16e-1)" "unprognostic (8.38e-3)" "unprognostic (3.04e-1)" "unprognostic (1.13e-1)" "unprognostic (7.56e-2)" "unprognostic (1.02e-1)" "unprognostic (5.74e-3)" "unprognostic (5.50e-3)" "unprognostic (8.78e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (5.45e-4)" "unprognostic (2.14e-2)" "unprognostic (1.92e-1)" "unprognostic (5.65e-2)" "unprognostic (8.84e-2)" 18.2 4.2 10.4 4.9 16.1 4.3 15.0 12.1 9.3 14.3 0.0 19.8 4.3 12.7 0.2 16.3 11.9 0.9 14.9 8.6 5.5 11.8 9.2 22.2 3.0 13.5 12.3 5.1 14.0 0.7 6.3 2.6 9.8 15.4 0.6 0.6 10.7 3.1 5.0 24.2 14.2 1.3 9.7 24.8 10.0 2.5 13.9 4.0 11.2 1.2 0.9 14.2 16.5 14.0 8.8 10.6 4.0 2.6 0.0 0.4 17.7 3.3 0.4 1.4 0.4 1.8 0.9 13.3 10.3 1.3 1.6 47.0 1.0 8.6 0.1 32.3 2.0 5.5 6.1 0.6 2.1 6.9 39.7 0.3 16.7 1.4 1.9 0.7 9.0 3.7 3.6 1.1 0.0 9.0 72.3 13.1 8.4 2.9 7.7 15.7 9.2 19.3 0.6 4.2 0.0 0.7 6.1 4.3 3.4 1.0 3.2 10.4 22.7 5.0 9.3 5.9 4.3 2.4 2.6 4.1 3.7 5.0 26.1 0.2 0.4 0.6 0.3 0.1 0.1 0.1 0.1 0.5 0.3 0.0 0.1 0.3 2.3 0.7 0.1 0.1 0.1 0.5 10.4 16.1 12.1 9.3 8.6 5.5 13.5 12.3 9.8 9.7 13.9 14.0 56.2 9.6 21.9 67.3 8.4 24.9 12.3 35.1 23.9 0.8 10.7 12.4 11.0 5.7 16.3 1.8 2.1 1.1 14.2 11.8 0.0 5.1 0.3 12.3 9.9 53.2 2.4 5.2 0.3 4.0 2.2 6.4 1.1 17.3 34.9 1.0 68.2 7.7 9.3 1.7 0.4 14.8 18.3 10.1 17.5 0.3 1.2 15.2 7.2 18.7 14.3 46.6 24.7 33.7 19.6 2.1 11.5 0.7 5.7 8.4 4.1 3.4 3.8 2.0 6.6 14.7 18.4 0.2 3.3 20.6 29.8 1.1 15.0 1.4 28.8 15.6 NR5A2 "B1F2, FTF, FTZ-F1, FTZ-F1beta, hB1F, hB1F-2, LRH-1, LRH1" ENSG00000116833 "Nuclear receptor subfamily 5 group A member 2" O00482 1 200027614-200177420 "Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 17.8;liver: 38.6;pancreas: 61.1" "Cell type enriched" "Detected in many" 5 "Granulosa cells: 276.2" "Cancer enhanced" "Detected in many" "liver cancer: 6.6" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "basophil: 3.2;neutrophil: 1.5" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Cell line enhanced" "Detected in some" "A549: 25.0;CACO-2: 6.2;HAP1: 14.9;HMC-1: 6.4;HUVEC TERT2: 20.4" "Region enhanced" "Detected in single" "hypothalamus: 1.2" "Not detected" "Not detected" "HPA005455, HPA017067" Approved Uncertain "Nuclear speckles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles" "HPA005455: AB_1078140, HPA017067: AB_1844767" "unprognostic (7.47e-2)" "unprognostic (1.43e-1)" "unprognostic (5.84e-2)" "unprognostic (1.56e-2)" "unprognostic (1.19e-2)" "unprognostic (6.63e-3)" "unprognostic (4.46e-2)" "unprognostic (3.78e-2)" "unprognostic (3.34e-1)" "unprognostic (8.50e-2)" "unprognostic (4.64e-2)" "unprognostic (1.44e-1)" "unprognostic (1.00e-7)" "unprognostic (5.48e-2)" "unprognostic (5.07e-2)" "unprognostic (9.23e-2)" "unprognostic (1.37e-1)" 5.4 0.4 0.5 2.6 0.2 0.9 3.7 0.5 0.3 3.4 0.2 11.9 17.4 3.3 1.4 0.9 2.2 8.0 1.0 0.3 2.8 0.7 38.6 2.7 2.1 0.7 0.6 1.0 61.1 0.4 0.1 0.4 0.8 1.6 13.1 0.2 0.5 0.8 1.1 1.1 17.8 4.3 0.4 0.2 1.3 0.8 0.8 0.5 0.9 0.7 1.4 1.8 1.2 0.7 0.0 25.0 0.0 0.1 0.0 0.2 0.6 0.0 0.4 0.0 0.0 6.2 0.1 0.0 0.0 0.0 0.7 0.7 14.9 0.0 0.0 3.3 1.1 0.0 0.3 2.7 0.5 0.1 6.4 0.1 0.0 0.0 0.1 0.0 20.4 0.1 0.0 0.3 0.0 0.6 0.0 0.4 0.9 0.0 0.3 0.4 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.1 1.7 4.7 0.3 0.1 1.0 0.2 0.1 0.2 3.4 2.3 2.6 0.3 0.2 0.1 3.2 0.4 0.4 0.2 0.2 0.2 0.3 0.3 0.3 0.1 0.4 0.4 0.3 1.5 0.5 0.2 0.5 0.4 0.1 0.5 0.2 0.5 0.3 0.3 2.8 0.7 0.6 0.8 0.4 0.8 0.7 23.7 0.0 1.7 0.3 0.2 1.9 0.1 0.0 0.0 0.2 0.2 0.0 9.9 32.9 0.0 0.0 0.0 0.0 0.3 37.5 0.0 38.2 0.4 0.3 0.3 32.4 4.9 2.7 0.4 54.5 0.0 0.8 0.0 0.2 13.3 276.2 38.6 38.5 0.1 0.0 0.6 13.8 0.0 4.9 1.5 0.3 0.6 0.6 0.0 0.0 3.1 0.0 0.0 1.0 0.3 22.0 21.8 0.0 1.2 0.3 49.9 0.0 0.8 0.3 0.0 0.5 6.1 0.1 0.1 0.0 1.4 0.0 0.3 0.1 32.3 0.2 NRIP3 C11orf14 ENSG00000175352 "Nuclear receptor interacting protein 3" Q9NQ35 11 8980576-9004049 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.9;retina: 24.5;testis: 43.5" "Cell type enhanced" "Detected in many" "Early spermatids: 545.3;Horizontal cells: 242.3;Late spermatids: 478.6;Spermatocytes: 189.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 13.1" "Lineage enriched" "Detected in many" 12 "granulocytes: 13.1" "Cell line enhanced" "Detected in many" "HMC-1: 51.4;SiHa: 34.3;U-87 MG: 47.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058827, HPA072961" Approved Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA058827: AB_2683829, HPA072961: " "unprognostic (2.05e-1)" "unprognostic (1.42e-1)" "unprognostic (8.84e-3)" "unprognostic (5.43e-3)" "unprognostic (1.66e-1)" "unprognostic (2.68e-1)" "unprognostic (2.03e-4)" "unprognostic (1.25e-1)" "unprognostic (1.88e-1)" "unprognostic (3.63e-2)" "unprognostic (1.04e-2)" "unprognostic (1.11e-1)" "unprognostic (1.33e-1)" "unprognostic (1.13e-1)" "unprognostic (1.41e-1)" "unprognostic (5.88e-3)" "unprognostic (1.30e-1)" 1.1 10.2 16.7 1.6 13.4 13.8 3.9 23.2 42.1 3.4 0.0 1.5 0.5 3.2 3.1 0.8 2.2 1.6 1.2 72.9 20.8 1.4 0.2 0.8 0.8 20.5 18.4 0.5 0.4 5.4 1.5 0.8 23.6 0.7 0.6 24.5 0.6 0.9 0.3 0.6 0.6 2.3 25.1 0.5 2.5 43.5 31.6 0.9 0.9 0.2 0.6 1.3 0.7 17.2 0.0 0.9 1.9 0.3 0.7 2.7 0.1 20.3 8.0 16.2 16.9 3.1 1.8 0.1 3.0 5.9 9.6 0.2 5.5 0.5 28.0 1.7 8.5 2.2 1.2 0.2 1.4 26.5 51.4 3.7 0.3 16.7 0.1 17.1 13.3 4.4 4.2 0.2 15.0 0.0 1.3 8.6 6.6 0.1 0.0 0.0 2.8 0.0 0.3 1.2 5.4 1.7 34.3 0.9 5.3 1.4 3.5 2.5 16.6 24.7 11.8 1.4 0.1 0.1 0.0 0.0 47.9 3.1 12.3 13.1 0.1 2.0 0.1 0.3 0.2 0.1 0.5 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 1.1 0.3 16.7 13.4 23.2 42.1 72.9 20.8 20.5 18.4 23.6 25.1 31.6 17.2 4.0 0.0 1.3 1.0 1.7 2.2 5.7 0.5 0.0 19.6 12.1 8.9 1.6 0.0 0.4 0.0 10.4 0.4 7.4 0.6 5.9 0.4 545.3 3.7 4.1 2.5 5.3 2.7 11.5 1.1 0.5 2.5 7.1 6.6 15.8 2.4 0.0 0.0 12.1 242.3 96.3 0.5 8.2 3.1 17.2 478.6 6.8 12.8 3.6 0.0 0.6 4.4 0.0 4.5 1.6 8.2 0.1 5.7 1.2 3.5 0.1 0.0 0.1 10.6 0.0 6.0 3.6 189.8 44.0 0.9 1.0 1.0 5.5 5.6 0.2 4.2 NRN1 NRN ENSG00000124785 "Neuritin 1" Q9NPD7 6 5997999-6007605 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 98.9;parathyroid gland: 81.0" "Cell type enhanced" "Detected in many" "Adipocytes: 262.9;Endothelial cells: 115.3;Excitatory neurons: 71.9;Extravillous trophoblasts: 64.7;Hepatic stellate cells: 160.3" "Cancer enhanced" "Detected in all" "glioma: 38.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "MAIT T-cell: 2.6;neutrophil: 2.2" "Group enriched" "Detected in many" 7 "granulocytes: 2.2;T-cells: 2.6" "Cell line enhanced" "Detected in many" "ASC diff: 140.0;ASC TERT1: 107.6;fHDF/TERT166: 147.5;JURKAT: 134.8;REH: 196.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 23000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 14: REH - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (6.24e-2)" "unprognostic (2.47e-2)" "unprognostic (1.35e-2)" "unprognostic (1.22e-1)" "unprognostic (1.26e-2)" "unprognostic (5.57e-2)" "unprognostic (4.70e-3)" "unprognostic (2.02e-2)" "unprognostic (1.03e-1)" "unprognostic (1.49e-1)" "unprognostic (1.67e-2)" "unprognostic (3.35e-1)" "prognostic unfavorable (4.79e-5)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (2.90e-1)" "unprognostic (4.37e-3)" 66.4 5.1 49.1 6.4 44.9 0.5 64.2 46.0 80.8 16.2 17.0 21.3 3.7 9.4 4.0 8.2 13.6 11.2 19.7 98.9 27.7 8.2 4.4 15.6 9.6 30.4 29.9 4.7 2.9 81.0 12.3 42.1 32.5 10.1 4.7 23.4 8.7 7.4 17.3 18.8 10.8 10.5 22.1 15.7 10.3 0.6 60.1 3.6 9.4 16.1 3.5 13.8 17.0 45.9 16.7 0.6 1.4 0.1 140.0 107.6 19.1 2.6 0.0 11.8 16.1 0.2 0.1 0.0 2.5 147.5 25.0 0.5 43.3 0.0 11.4 26.1 21.2 13.7 0.0 0.0 0.0 58.0 43.7 17.3 0.0 10.5 0.0 0.1 57.4 134.8 0.2 0.6 42.5 0.1 89.7 2.6 0.1 0.0 0.0 196.3 47.7 0.4 0.2 0.2 24.9 9.2 0.0 0.8 13.9 0.2 0.4 16.4 12.1 56.4 1.6 21.4 36.5 0.1 2.2 0.9 85.8 0.2 8.9 0.0 0.1 0.0 0.1 0.1 2.6 0.3 0.2 0.3 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.2 0.0 0.1 49.1 44.9 46.0 80.8 98.9 27.7 30.4 29.9 32.5 22.1 60.1 45.9 262.9 0.0 1.3 7.2 1.6 10.5 0.1 0.0 1.2 6.7 1.4 2.4 2.5 1.5 0.0 0.0 2.1 1.5 1.0 0.0 0.0 0.1 0.1 0.0 0.1 115.3 0.0 0.0 71.9 0.5 64.7 15.9 0.0 0.1 0.0 0.0 160.3 0.9 1.8 3.3 3.0 0.0 0.0 4.1 21.5 0.4 0.9 1.4 16.0 8.4 0.5 4.5 0.0 13.6 8.3 0.2 0.0 0.0 1.4 0.4 0.0 0.0 0.0 20.2 0.0 4.4 18.3 0.4 0.3 0.6 11.2 1.4 1.9 0.1 0.0 0.7 ODF2L KIAA1229 ENSG00000122417 "Outer dense fiber of sperm tails 2 like" Q9ULJ1 1 86346824-86396342 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 335.7;Respiratory ciliated cells: 361.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028020, HPA028095, HPA028333" Uncertain NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" "HPA028020: AB_10601670, HPA028095: AB_10611385, HPA028333: AB_10601007" "unprognostic (4.81e-2)" "unprognostic (3.11e-1)" "unprognostic (1.03e-1)" "unprognostic (4.72e-2)" "unprognostic (2.92e-2)" "unprognostic (3.80e-3)" "unprognostic (5.61e-3)" "unprognostic (2.25e-1)" "unprognostic (2.08e-3)" "unprognostic (1.07e-1)" "unprognostic (6.27e-2)" "unprognostic (5.25e-2)" "prognostic unfavorable (4.69e-7)" "unprognostic (2.40e-1)" "unprognostic (5.86e-2)" "unprognostic (2.40e-1)" "unprognostic (5.04e-3)" 22.6 20.2 14.0 14.0 15.8 17.1 23.0 16.8 20.0 21.7 14.3 18.4 8.3 18.1 23.3 17.6 23.7 15.2 13.4 14.2 12.7 24.5 7.1 22.9 16.6 13.2 14.8 18.8 11.4 7.2 28.1 10.1 8.1 20.0 14.8 41.2 15.5 10.5 5.2 11.9 22.8 9.7 9.0 36.5 8.7 13.3 15.2 21.9 22.1 3.7 13.2 15.3 17.6 16.8 30.0 7.9 19.7 15.1 21.0 35.8 20.6 28.6 17.4 27.6 32.0 6.2 16.3 0.7 26.3 15.3 35.2 15.3 8.1 16.7 23.6 14.1 12.8 7.3 24.5 0.6 15.9 13.1 9.3 16.5 20.2 41.7 11.4 19.9 45.3 19.8 10.2 6.8 16.4 4.0 15.7 13.8 24.1 6.5 14.5 21.0 14.8 3.2 27.7 40.0 19.5 14.1 25.8 26.2 54.9 30.7 8.5 12.6 41.7 23.0 21.4 31.8 29.4 1.9 1.0 12.3 5.4 6.7 26.5 5.6 2.2 13.6 26.1 3.4 51.5 20.9 30.2 21.0 2.4 21.2 19.3 18.8 6.3 14.8 4.1 12.7 31.8 4.9 14.0 15.8 16.8 20.0 14.2 12.7 13.2 14.8 8.1 9.0 15.2 16.8 72.9 93.0 76.2 22.5 54.0 25.0 54.6 49.0 15.4 139.3 67.0 49.3 12.0 21.5 133.2 80.9 141.8 7.3 73.9 23.1 23.5 61.9 48.5 335.7 57.3 78.7 41.3 16.6 119.1 27.1 35.1 52.5 13.3 70.6 36.7 55.9 72.8 3.9 15.5 57.2 107.2 68.5 42.7 21.2 19.7 10.3 24.8 18.6 56.9 38.4 21.8 28.8 80.3 29.1 49.9 55.9 28.1 28.6 38.9 16.5 9.3 23.1 361.9 120.3 19.7 24.3 32.1 64.0 27.4 19.2 17.3 2.9 106.4 60.6 28.2 67.3 OPN1SW "BCP, BOP, CBT" ENSG00000128617 "Opsin 1, short wave sensitive" P03999 7 128772485-128775794 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 84 "retina: 41.0" "Cell type enriched" "Detected in some" 12 "Cone photoreceptor cells: 41.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "LHCN-M2: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA013562, HPA014083" Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytokinetic bridge,Cytosol" Yes NA "Cluster 79: Retina - Phototransduction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "Nuclear bodies, Cytokinetic bridge, Cytosol" "HPA013562: AB_2668850, HPA014083: AB_2668938" "unprognostic (2.88e-1)" "unprognostic (5.17e-2)" "unprognostic (2.22e-2)" "unprognostic (1.33e-2)" "unprognostic (2.55e-2)" "unprognostic (2.16e-1)" "prognostic unfavorable (8.50e-5)" "unprognostic (1.13e-1)" "unprognostic (1.27e-1)" "unprognostic (6.33e-2)" "unprognostic (3.79e-1)" "unprognostic (6.05e-2)" "prognostic unfavorable (2.26e-8)" "prognostic unfavorable (5.98e-8)" "unprognostic (2.53e-1)" "unprognostic (8.99e-2)" "prognostic unfavorable (9.33e-4)" 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.2 0.4 0.0 0.4 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 41.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.0 0.0 41.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 P2RY8 P2Y8 ENSG00000182162 "P2Y receptor family member 8" Q86VZ1 X 1462581-1537185 "Cancer-related genes, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 31.2;lymphoid tissue: 40.1" "Group enriched" "Detected in some" 4 "B-cells: 42.0;dendritic cells: 56.2;monocytes: 26.1;NK-cells: 56.7;Plasma cells: 49.3;T-cells: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 119.2;MOLT-4: 60.6;NB-4: 59.6;RPMI-8226: 74.3;THP-1: 73.7;U-266/70: 96.8;U-698: 192.8;U-937: 60.6" "Low region specificity" "Detected in single" HPA003631 Enhanced NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA003631: AB_1079543" "unprognostic (4.32e-2)" "unprognostic (3.22e-5)" "unprognostic (6.31e-2)" "unprognostic (2.51e-2)" "unprognostic (1.17e-1)" "prognostic favorable (7.80e-5)" "prognostic favorable (1.73e-4)" "unprognostic (5.27e-3)" "unprognostic (5.76e-3)" "unprognostic (5.52e-3)" "prognostic favorable (6.54e-4)" "unprognostic (4.29e-2)" "unprognostic (8.45e-3)" "unprognostic (2.90e-1)" "unprognostic (4.00e-2)" "unprognostic (3.55e-1)" "unprognostic (2.80e-1)" 3.5 4.6 0.4 19.2 0.5 31.2 2.4 0.8 1.1 0.7 0.8 3.4 3.4 0.8 0.9 1.3 0.7 3.8 4.9 0.2 0.7 3.6 1.9 3.0 40.1 1.5 0.5 1.1 2.1 2.1 2.1 1.2 0.9 1.5 3.2 0.7 3.4 1.1 2.6 1.8 7.5 1.4 0.5 20.0 5.1 0.4 1.4 16.4 7.9 1.4 33.4 4.4 0.5 1.8 0.6 0.5 0.5 1.5 0.0 0.0 1.3 0.2 0.1 0.0 0.1 0.4 0.7 119.2 0.6 0.0 0.5 0.5 0.0 0.1 0.0 4.7 0.4 1.0 1.3 6.1 0.1 53.2 12.3 0.1 0.1 0.1 0.0 1.1 0.0 35.1 1.1 48.9 0.1 0.1 60.6 59.6 0.7 0.1 1.3 54.1 0.6 74.3 0.1 0.9 0.2 0.8 0.4 1.1 0.3 1.1 0.6 73.7 0.3 1.0 1.1 0.5 0.3 96.8 19.6 192.8 0.2 60.6 0.2 49.9 18.9 31.1 58.6 12.7 53.6 34.2 44.5 55.8 13.6 38.3 34.7 36.4 11.3 37.5 5.2 3.6 37.6 53.3 0.4 0.5 0.8 1.1 0.2 0.7 1.5 0.5 0.9 0.5 1.4 1.8 5.9 0.0 1.8 0.3 42.0 0.4 0.0 0.0 0.0 0.7 0.3 0.0 1.2 0.0 0.6 1.8 0.0 0.0 56.2 0.1 0.0 0.0 0.0 0.1 0.1 5.2 0.0 9.9 0.7 0.2 0.0 0.4 2.6 0.1 1.3 0.3 3.9 0.3 1.9 0.0 0.7 0.0 0.0 11.2 1.8 0.0 0.0 8.7 1.8 1.9 26.1 0.0 56.7 1.0 0.4 0.0 0.0 0.0 49.3 0.1 0.0 0.3 0.0 0.2 0.0 0.1 0.8 0.0 0.0 0.0 0.4 0.0 40.7 0.9 0.2 0.0 PARP14 "ARTD8, KIAA1268, pART8" ENSG00000173193 "Poly(ADP-ribose) polymerase family member 14" Q460N5 3 122680839-122730840 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 246.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 74.7;BJ hTERT+ SV40 Large T+ RasG12V: 113.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA008846, HPA012063" Supported Supported Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 44: Endometrium - Transcription" Cytosol "HPA008846: AB_1854982, HPA012063: AB_1854981" "unprognostic (4.38e-2)" "unprognostic (1.07e-2)" "unprognostic (1.25e-1)" "unprognostic (1.95e-2)" "unprognostic (2.56e-1)" "unprognostic (2.50e-3)" "unprognostic (1.87e-1)" "unprognostic (1.33e-1)" "unprognostic (1.44e-1)" "unprognostic (4.20e-2)" "unprognostic (1.74e-3)" "unprognostic (1.62e-2)" "prognostic unfavorable (1.79e-4)" "unprognostic (7.87e-2)" "unprognostic (3.82e-2)" "unprognostic (1.58e-3)" "unprognostic (1.71e-2)" 14.0 12.6 4.3 24.3 5.1 20.1 11.3 3.6 2.7 11.4 5.5 11.5 15.3 8.2 2.4 9.0 10.7 15.2 11.1 2.8 5.1 14.9 24.5 33.5 24.0 15.1 5.9 9.2 7.8 7.3 7.6 17.8 8.6 13.0 8.7 1.1 11.7 7.2 5.0 5.3 17.5 10.2 10.9 37.4 11.7 2.2 8.9 15.4 14.7 8.3 26.8 13.7 9.4 7.8 15.6 13.0 8.0 8.3 9.1 26.2 0.0 6.1 40.1 74.7 113.1 6.9 28.7 0.0 24.2 13.4 41.8 11.5 11.9 11.6 15.0 24.0 1.5 14.6 5.8 8.7 20.4 6.4 6.8 14.7 4.7 13.0 4.8 16.4 32.2 12.3 7.0 22.7 2.1 7.9 24.8 1.5 1.1 2.1 11.1 34.2 8.3 4.3 9.5 16.2 0.6 0.0 15.3 3.1 14.1 0.8 5.7 9.3 22.0 4.0 9.4 2.3 5.5 8.7 1.6 2.7 12.0 13.8 7.2 13.1 10.8 5.8 8.6 13.7 7.2 12.8 4.5 5.6 5.6 20.3 3.6 4.1 29.5 9.5 14.7 0.7 9.9 4.3 4.3 5.1 3.6 2.7 2.8 5.1 15.1 5.9 8.6 10.9 8.9 7.8 111.5 246.8 98.4 17.3 115.3 16.8 17.0 35.9 13.1 2.1 19.6 15.6 14.6 24.3 65.9 25.8 4.2 14.1 64.9 43.0 3.9 36.0 0.3 118.8 59.8 94.7 10.7 18.5 0.5 41.2 28.4 37.2 24.5 149.8 32.2 69.6 67.1 32.5 36.5 0.0 3.0 18.2 26.4 61.6 39.9 2.1 28.0 83.9 16.0 124.6 132.2 15.1 58.7 47.3 1.1 44.0 20.2 17.3 50.9 31.8 29.5 11.5 73.0 1.0 13.1 32.7 30.3 1.9 1.1 13.7 10.5 4.8 51.4 42.8 16.0 25.9 PCDH12 VE-cadherin-2 ENSG00000113555 "Protocadherin 12" Q9NPG4 5 141943581-141969741 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Epilepsy, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 30.2" "Group enriched" "Detected in some" 4 "Adipocytes: 38.5;Endothelial cells: 40.0;Hepatic stellate cells: 41.0;Hofbauer cells: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 4.6" "Lineage enriched" "Detected in single" 41 "monocytes: 4.6" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 25.9;Karpas-707: 66.5;U-937: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051242 Uncertain "Secreted to blood" NA NA 14000000 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA051242: AB_2681402" "unprognostic (6.62e-2)" "unprognostic (6.94e-2)" "unprognostic (4.74e-3)" "unprognostic (4.12e-2)" "unprognostic (3.99e-1)" "unprognostic (3.25e-1)" "unprognostic (4.35e-1)" "unprognostic (1.88e-2)" "unprognostic (4.29e-2)" "unprognostic (2.76e-1)" "unprognostic (9.99e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.11e-2)" "unprognostic (5.21e-2)" "unprognostic (9.37e-2)" "unprognostic (9.33e-2)" 13.4 5.0 0.8 2.5 0.9 0.5 4.9 2.5 1.7 2.7 1.2 2.0 2.0 2.8 0.4 2.1 2.1 4.0 10.8 0.6 0.8 6.0 4.0 15.5 2.6 0.5 0.3 1.7 1.4 2.9 3.6 30.2 0.6 1.9 1.3 1.6 1.4 2.3 4.0 1.7 2.1 5.2 0.3 18.6 2.0 1.1 1.4 0.8 6.5 5.1 1.0 3.2 1.9 0.3 0.1 0.1 1.9 0.5 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.1 5.0 0.1 0.6 0.1 0.0 0.0 0.0 0.4 0.6 1.4 0.2 0.1 0.2 0.5 0.2 0.0 0.0 0.4 0.0 0.4 25.9 0.3 0.0 66.5 0.0 0.4 0.1 0.3 0.5 0.0 0.3 0.5 0.2 3.0 0.0 0.1 0.3 0.7 0.1 0.1 0.3 0.2 0.0 1.8 1.8 0.6 0.1 0.9 0.1 0.4 0.4 0.1 0.4 11.7 2.2 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.8 0.9 2.5 1.7 0.6 0.8 0.5 0.3 0.6 0.3 1.4 0.3 38.5 0.0 1.1 0.0 0.5 0.6 0.0 0.0 1.2 1.3 0.1 0.1 4.0 0.0 0.0 0.0 2.1 0.3 0.3 0.0 3.9 0.1 1.7 0.1 0.1 40.0 0.0 0.0 0.2 0.0 0.3 0.9 0.0 0.1 1.3 0.0 41.0 0.5 34.6 0.0 0.2 0.0 0.0 8.5 0.3 2.5 0.0 1.5 1.8 6.5 0.3 0.5 0.0 1.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.4 0.0 0.4 0.0 0.7 1.0 0.0 0.2 0.2 0.3 0.5 0.2 1.4 0.0 0.2 PCSK6 "PACE4, SPC4" ENSG00000140479 "Proprotein convertase subtilisin/kexin type 6" P29122 15 101289784-101525202 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 153.6;liver: 160.0;lymphoid tissue: 81.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 231.6;Horizontal cells: 196.9;Oligodendrocytes: 561.9;Theca cells: 106.5" "Cancer enhanced" "Detected in many" "liver cancer: 8.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 47.2;CACO-2: 35.7;HEK 293: 60.3;Hep G2: 53.8;OE19: 65.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004774 Uncertain "Secreted to extracellular matrix" NA NA 480000 "Cluster 15: NK-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA004774: AB_1079583" "prognostic favorable (9.99e-4)" "unprognostic (1.09e-1)" "unprognostic (4.37e-2)" "unprognostic (2.46e-2)" "unprognostic (9.83e-2)" "unprognostic (8.14e-2)" "unprognostic (2.20e-3)" "unprognostic (8.56e-2)" "unprognostic (2.16e-1)" "unprognostic (2.39e-2)" "unprognostic (3.85e-3)" "unprognostic (2.01e-1)" "prognostic unfavorable (7.06e-7)" "unprognostic (2.02e-1)" "unprognostic (1.87e-1)" "unprognostic (1.15e-1)" "unprognostic (1.03e-2)" 5.3 2.2 17.5 3.0 67.3 1.1 11.2 57.8 37.0 2.2 4.2 16.5 6.8 2.0 3.3 9.0 2.8 3.1 20.0 19.3 34.1 3.2 160.0 3.6 2.5 113.0 64.5 6.1 2.6 0.6 5.1 32.0 95.6 3.1 14.8 7.6 2.8 0.6 11.4 10.1 10.1 3.6 42.9 81.4 9.8 13.0 54.0 20.9 2.2 16.3 1.8 3.7 2.6 153.6 19.7 14.6 2.6 0.9 0.2 0.4 47.2 0.7 2.5 0.0 0.1 35.7 8.3 0.4 2.4 0.6 1.1 11.4 12.5 1.5 0.0 2.8 60.3 33.5 8.4 53.8 1.6 4.5 0.4 0.3 7.5 0.2 0.2 0.2 0.1 4.3 24.5 0.2 0.0 8.8 0.1 4.7 9.3 65.9 6.5 0.2 0.4 4.4 4.4 25.4 7.3 8.6 26.2 1.5 9.1 6.6 2.2 21.9 0.2 0.3 1.2 0.3 0.2 0.5 0.6 0.7 0.2 0.6 7.3 0.8 0.2 0.9 0.2 0.4 0.3 0.5 0.4 0.2 0.1 1.0 0.6 0.5 0.4 3.3 1.3 0.4 0.1 1.2 17.5 67.3 57.8 37.0 19.3 34.1 113.0 64.5 95.6 42.9 54.0 153.6 1.7 3.2 0.6 2.9 1.3 0.4 0.3 0.9 0.6 1.7 15.4 6.6 2.0 8.6 1.4 1.8 20.9 6.7 0.6 22.6 0.0 0.6 1.6 4.7 21.6 4.9 0.0 3.2 19.4 0.8 24.3 15.5 1.5 6.9 0.0 4.2 12.5 231.6 1.4 196.9 30.8 3.7 0.0 5.2 1.1 2.4 10.5 1.7 0.0 5.6 1.0 1.7 3.1 25.6 561.9 7.3 8.2 0.0 0.0 1.7 2.3 0.1 1.2 1.6 0.0 2.0 1.0 4.7 2.4 0.9 0.1 3.3 1.0 106.5 8.5 0.2 PDCD1LG2 "B7-DC, bA574F11.2, Btdc, CD273, PD-L2, PDL2" ENSG00000197646 "Programmed cell death 1 ligand 2" Q9BQ51 9 5510531-5571282 "Cancer-related genes, CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 17.9;Langerhans cells: 13.1;Microglial cells: 12.2;monocytes: 26.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 71.4;BJ hTERT+: 111.6;HDLM-2: 88.1;TIME: 49.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013411 Approved Uncertain Cytosol "Secreted - unknown location" NA NA 31000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA013411: AB_1855102" "unprognostic (3.93e-2)" "unprognostic (1.90e-1)" "unprognostic (3.51e-3)" "unprognostic (6.68e-3)" "unprognostic (7.66e-2)" "unprognostic (6.77e-2)" "unprognostic (5.72e-2)" "unprognostic (2.91e-1)" "unprognostic (1.68e-1)" "unprognostic (4.37e-3)" "unprognostic (5.79e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (1.15e-4)" "unprognostic (5.00e-2)" "unprognostic (4.66e-2)" "unprognostic (2.01e-1)" "unprognostic (7.51e-3)" 4.4 0.8 0.4 6.9 0.6 0.3 4.3 0.5 0.5 2.5 0.3 1.7 0.7 2.2 1.2 2.0 2.4 3.4 2.7 0.4 0.8 1.2 4.2 7.1 10.4 1.1 0.6 1.6 0.6 0.4 0.2 4.8 1.1 1.0 2.1 0.0 1.3 1.4 1.5 1.4 1.5 3.1 0.9 15.1 1.4 0.6 0.7 5.0 1.0 2.2 6.2 4.2 2.2 1.3 6.0 0.0 0.0 0.0 4.7 5.4 0.1 71.4 111.6 33.7 40.4 0.0 0.3 0.0 0.2 29.2 4.8 0.5 0.1 9.7 33.3 88.1 0.0 0.0 0.0 0.0 26.5 0.0 0.0 5.0 0.1 15.8 18.5 9.7 22.4 0.0 0.0 8.5 41.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.0 0.7 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.2 0.0 0.1 49.7 24.0 1.4 11.8 20.1 1.2 0.1 0.1 13.6 0.0 3.0 1.5 0.3 0.0 0.5 1.4 0.6 0.2 0.7 0.3 0.3 0.1 0.0 0.3 0.7 0.0 0.1 0.0 1.1 0.3 0.4 0.6 0.5 0.5 0.4 0.8 1.1 0.6 1.1 0.9 0.7 1.3 6.1 6.4 0.5 1.6 0.4 1.0 0.1 0.7 1.8 0.0 0.2 1.5 0.1 0.0 0.7 0.0 0.0 0.6 0.4 0.0 0.0 0.1 0.0 0.0 0.4 2.2 0.0 0.0 1.6 0.2 17.9 6.7 0.5 0.0 3.8 0.2 6.8 0.0 2.9 0.0 1.4 0.0 0.0 5.3 13.1 0.0 5.9 2.5 1.8 12.2 26.4 0.0 0.0 1.0 2.4 3.7 0.0 2.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 2.2 3.1 0.0 0.0 0.3 1.0 0.8 1.1 0.1 0.0 0.1 PDE2A ENSG00000186642 "Phosphodiesterase 2A" O00408 11 72576141-72674591 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 197.0" "Group enriched" "Detected in many" 6 "Adipocytes: 114.9;Endothelial cells: 58.5;Enteroendocrine cells: 34.4;Excitatory neurons: 70.1;Hepatic stellate cells: 118.2;Inhibitory neurons: 35.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 75.1;basal ganglia: 84.7;cerebral cortex: 102.1;hippocampal formation: 84.4;white matter: 48.3" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.8;T-cells: 7.3" "Cell line enriched" "Detected in some" 8 "HeLa: 513.6" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 5 "amygdala: 83.5;basal ganglia: 146.9;cerebral cortex: 90.5;hippocampal formation: 94.0" "CAB009752, HPA031192" Enhanced Supported Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB009752: AB_2268159, HPA031192: AB_2673781" "unprognostic (1.92e-1)" "unprognostic (1.52e-3)" "unprognostic (4.58e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-1)" "unprognostic (2.50e-1)" "prognostic favorable (1.76e-6)" "unprognostic (3.06e-2)" "unprognostic (1.35e-1)" "unprognostic (3.01e-3)" "unprognostic (3.13e-3)" "unprognostic (1.50e-2)" "unprognostic (1.77e-2)" "unprognostic (2.85e-3)" "unprognostic (6.31e-2)" "unprognostic (7.72e-2)" "unprognostic (7.96e-4)" 89.2 44.1 75.1 5.1 84.7 4.7 83.6 0.0 102.1 38.1 0.0 34.6 6.0 27.2 8.3 18.6 39.3 22.7 41.1 84.4 7.0 32.5 19.4 12.6 6.7 6.4 5.1 11.6 6.9 5.5 11.8 12.0 10.1 20.7 8.9 3.0 9.2 10.7 16.8 18.1 18.7 18.5 0.0 197.0 17.1 7.4 17.9 3.8 24.1 28.9 3.5 28.8 27.1 48.3 0.3 0.2 0.7 0.2 0.2 0.1 0.3 0.1 0.2 0.2 0.4 0.4 2.5 0.8 12.2 0.2 1.9 0.2 0.9 0.1 0.1 0.1 0.1 0.0 513.6 0.8 0.9 0.0 7.8 0.1 1.1 2.7 20.5 1.1 11.3 0.5 0.8 0.9 0.1 0.0 0.2 0.2 7.4 0.2 14.0 0.0 0.2 1.4 0.1 0.3 44.5 2.4 0.4 0.2 2.2 0.7 0.3 0.1 65.2 0.1 9.4 3.5 0.4 0.4 0.2 0.1 3.9 0.1 0.6 0.0 0.6 0.0 7.3 0.8 4.2 2.8 4.3 4.3 1.0 1.8 2.7 2.3 0.1 0.0 0.4 0.0 1.8 1.5 75.1 84.7 0.0 102.1 84.4 7.0 6.4 5.1 10.1 0.0 17.9 48.3 114.9 0.0 0.5 2.0 0.7 2.5 0.1 0.0 0.0 4.9 0.6 1.0 7.8 0.0 0.0 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.6 0.0 0.1 58.5 34.4 5.3 70.1 0.0 0.3 2.1 0.0 0.1 1.3 0.1 118.2 2.1 0.5 1.7 35.6 1.2 0.0 9.4 8.2 2.5 0.3 4.9 1.8 11.2 0.0 0.0 0.0 9.0 5.7 0.1 0.0 0.4 1.5 0.1 0.0 0.1 0.0 0.4 0.0 1.8 6.6 4.8 2.5 0.5 2.8 0.0 0.6 0.2 0.1 0.3 PDGFB "SIS, SSV" ENSG00000100311 "Platelet derived growth factor subunit B" P01127 22 39223359-39244982 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 75.0;Endothelial cells: 60.6;Langerhans cells: 44.3;Macrophages: 25.5;Pancreatic endocrine cells: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.0" "Lineage enriched" "Detected in many" 7 "T-cells: 10.0" "Cell line enhanced" "Detected in many" "A-431: 33.8;EFO-21: 69.2;HUVEC TERT2: 52.6;SK-BR-3: 53.5;TIME: 68.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011604, HPA011972, CAB018341" Supported Approved Vesicles "Secreted to blood" NA NA 4390000 950000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB011604: AB_2162180, CAB018341: AB_2162187, HPA011972: AB_1855134" "unprognostic (4.96e-2)" "unprognostic (8.94e-3)" "unprognostic (8.41e-2)" "unprognostic (2.66e-1)" "unprognostic (9.84e-2)" "unprognostic (4.46e-3)" "unprognostic (4.34e-1)" "prognostic unfavorable (3.67e-5)" "unprognostic (3.22e-2)" "unprognostic (2.07e-1)" "unprognostic (1.05e-1)" "unprognostic (8.68e-2)" "unprognostic (1.84e-3)" "unprognostic (5.12e-3)" "unprognostic (7.47e-2)" "unprognostic (6.50e-2)" "unprognostic (1.03e-1)" 32.6 6.4 14.7 7.1 10.7 0.4 24.0 10.3 22.2 7.5 4.8 20.6 4.9 8.9 5.2 6.2 7.2 11.7 31.2 12.0 9.8 17.0 3.7 28.1 7.4 13.6 12.4 3.8 8.8 8.9 4.0 40.2 12.0 7.6 3.5 0.8 10.6 5.2 18.7 10.3 9.1 9.2 10.6 6.6 7.9 3.4 16.0 2.1 16.1 11.0 1.6 8.5 6.6 9.4 33.8 2.6 8.4 0.0 0.0 0.0 9.9 0.1 0.4 0.2 0.0 13.0 10.3 0.0 69.2 0.0 3.1 12.4 0.5 2.8 0.0 0.1 0.2 0.7 1.1 4.8 4.3 0.0 18.1 0.0 0.3 0.0 0.4 0.9 52.6 0.0 1.3 6.1 1.9 13.7 0.1 0.1 3.2 8.1 3.4 0.0 0.3 22.8 27.7 0.1 0.2 0.0 0.6 53.5 0.2 6.0 24.3 0.1 68.1 0.1 6.4 0.1 7.5 0.1 0.4 0.3 0.1 1.5 31.3 0.0 0.0 0.0 7.3 0.1 10.0 0.0 4.3 5.6 0.0 0.0 3.6 1.9 0.1 0.0 0.4 1.3 2.3 2.1 14.7 10.7 10.3 22.2 12.0 9.8 13.6 12.4 12.0 10.6 16.0 9.4 75.0 0.0 1.1 0.0 0.6 2.8 1.2 3.8 1.2 0.7 5.1 7.1 3.1 0.0 1.3 7.3 0.0 7.3 4.0 0.1 0.0 20.0 1.3 4.0 0.7 60.6 1.8 0.0 2.8 3.6 6.5 1.6 0.0 5.6 0.0 13.1 16.8 1.4 7.7 0.0 0.9 0.7 4.1 2.6 44.3 0.1 0.6 25.5 1.8 14.0 1.1 0.3 0.0 0.0 0.2 54.7 0.0 0.0 0.0 2.7 0.1 1.9 0.9 0.1 6.6 4.7 9.6 0.3 1.6 1.1 1.4 4.5 2.0 1.2 0.1 0.6 PDIA5 "FLJ30401, PDIR" ENSG00000065485 "Protein disulfide isomerase family A member 5" Q14554 3 123067025-123225227 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 80.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 133.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 12.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030353, HPA030355" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" "Intracellular and membrane" NA NA 4700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Golgi apparatus" "Nucleoli fibrillar center" "HPA030353: AB_10599734, HPA030355: AB_10602200" "unprognostic (8.81e-2)" "unprognostic (2.25e-2)" "unprognostic (8.93e-2)" "prognostic favorable (4.55e-4)" "unprognostic (4.34e-2)" "unprognostic (2.10e-2)" "unprognostic (7.38e-2)" "unprognostic (2.41e-1)" "unprognostic (3.21e-2)" "unprognostic (4.02e-2)" "unprognostic (1.55e-1)" "unprognostic (2.26e-3)" "prognostic unfavorable (8.09e-11)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (1.06e-2)" "unprognostic (4.06e-3)" 17.9 23.6 0.3 15.2 0.3 17.9 13.8 0.2 1.4 14.5 2.7 20.1 13.9 12.4 30.2 6.1 14.0 19.6 9.9 0.6 0.8 14.5 80.2 17.7 11.1 0.5 0.6 11.5 26.6 10.7 12.7 47.4 0.4 32.3 25.0 4.2 13.7 7.9 4.2 8.8 12.8 17.0 0.3 10.1 33.4 15.3 0.9 4.5 30.8 4.3 12.0 17.9 9.5 0.7 24.0 14.6 17.7 21.5 80.3 71.9 95.0 44.9 74.5 24.5 66.9 47.8 21.6 0.0 57.6 69.9 15.7 12.5 7.8 27.4 25.7 1.1 8.8 10.4 3.9 56.7 33.2 26.5 1.4 62.3 40.2 16.6 34.5 26.1 84.0 10.1 13.6 60.4 16.9 29.6 7.2 31.3 13.1 54.5 15.6 6.7 13.0 67.5 20.7 13.9 19.3 11.4 22.0 24.0 40.4 28.7 21.4 32.3 47.2 6.2 19.5 29.4 12.3 18.1 5.0 10.8 20.2 21.0 21.5 0.0 9.3 0.3 1.4 2.4 2.3 3.5 1.0 0.8 5.5 1.1 0.6 0.6 0.2 0.5 0.5 12.8 0.0 2.3 0.3 0.3 0.2 1.4 0.6 0.8 0.5 0.6 0.4 0.3 0.9 0.7 17.2 19.2 30.7 2.6 5.6 5.0 6.0 6.4 3.4 13.1 6.9 4.7 2.7 35.8 11.3 5.5 39.6 41.8 3.1 5.4 0.0 32.2 1.6 5.4 13.1 24.3 8.4 5.5 9.6 28.6 133.6 20.7 30.5 21.1 3.8 7.3 37.5 50.1 12.1 0.0 7.1 36.9 0.0 7.8 5.5 2.0 24.2 4.4 8.8 5.6 5.0 2.3 0.0 1.0 2.5 11.9 7.6 22.2 40.1 18.1 3.5 5.3 6.4 28.4 13.1 3.6 17.6 1.3 1.5 3.4 4.1 50.2 3.1 23.3 15.1 4.5 PEA15 "HMAT1, HUMMAT1H, MAT1, MAT1H, PEA-15, PED, PED-PEA15, PED/PEA15" ENSG00000162734 "Proliferation and apoptosis adaptor protein 15" Q15121 1 160205380-160215376 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1106.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 246.3;monocytes: 267.6;Muller glia cells: 315.8" "Cancer enhanced" "Detected in all" "glioma: 466.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 78.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028356, HPA070820" Enhanced Supported Nucleoplasm,Cytosol NA NA 300000 "Cluster 7: Monocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" Cytosol Nucleoplasm "HPA028356: AB_10602814, HPA070820: AB_2732166" "unprognostic (1.29e-1)" "unprognostic (4.78e-2)" "unprognostic (1.05e-1)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (1.64e-2)" "unprognostic (1.99e-3)" "unprognostic (6.10e-2)" "unprognostic (4.57e-1)" "unprognostic (1.25e-1)" "unprognostic (6.31e-2)" "unprognostic (4.07e-2)" "prognostic unfavorable (6.53e-7)" "unprognostic (2.60e-2)" "unprognostic (1.39e-1)" "unprognostic (2.82e-3)" "unprognostic (1.24e-1)" 190.2 82.2 863.3 121.7 900.6 16.6 142.7 908.1 949.4 110.1 612.5 146.5 31.7 124.5 83.4 119.2 104.2 88.2 241.9 884.6 939.2 112.0 41.2 147.9 75.5 1028.2 1010.2 80.4 39.6 85.4 80.0 102.3 981.5 112.2 58.5 461.4 80.8 119.4 61.1 105.6 64.8 194.6 933.0 103.2 75.8 80.5 915.2 40.7 83.5 84.5 96.9 133.4 110.2 1106.4 139.2 46.8 190.5 82.5 344.5 191.5 63.6 593.2 503.3 471.6 328.5 103.7 72.3 63.4 210.9 729.4 226.6 146.4 71.5 181.7 365.3 34.4 40.2 52.4 32.5 26.7 423.9 17.8 62.0 161.8 100.7 260.2 328.5 259.6 360.7 45.7 55.1 111.8 640.6 68.3 21.0 41.1 127.0 160.9 134.3 34.4 200.6 43.8 173.0 71.0 38.0 100.0 310.4 207.6 179.9 409.4 128.1 122.6 487.7 311.3 246.4 234.4 254.5 88.1 59.5 118.7 287.1 33.2 450.8 1.3 39.3 5.2 8.4 78.2 6.5 18.9 6.2 6.9 56.7 13.5 3.8 4.2 1.8 7.9 38.7 25.0 7.9 14.9 863.3 900.6 908.1 949.4 884.6 939.2 1028.2 1010.2 981.5 933.0 915.2 1106.4 137.8 16.0 29.9 40.5 38.6 80.2 124.2 21.8 33.6 172.1 76.9 60.2 246.3 11.5 24.7 5.5 73.0 21.8 13.7 12.7 29.4 74.7 65.4 36.4 33.7 125.1 12.0 7.4 24.8 46.3 61.1 81.5 17.9 85.9 31.1 17.2 89.3 6.5 63.3 92.5 19.1 12.0 8.2 42.6 234.6 55.4 66.8 68.9 74.7 14.0 267.6 315.8 8.2 12.1 48.3 102.5 4.7 109.9 14.8 119.4 5.4 18.3 13.8 129.2 46.0 69.4 78.3 16.5 4.1 42.7 73.3 45.3 19.4 18.5 12.8 178.8 PELI1 ENSG00000197329 "Pellino E3 ubiquitin protein ligase 1" Q96FA3 2 64092652-64144420 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 228.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 224.1;Plasma cells: 318.8;Squamous epithelial cells: 208.0;Suprabasal keratinocytes: 217.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 76.9" "Group enriched" "Detected in all" 4 "granulocytes: 76.9;monocytes: 23.2" "Cell line enhanced" "Detected in many" "CACO-2: 58.8;U-698: 146.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053182 Approved Approved "Nucleoplasm,Nucleoli,Intermediate filaments" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Nucleoli, Intermediate filaments" "HPA053182: AB_2682072" "unprognostic (3.33e-2)" "unprognostic (3.43e-2)" "unprognostic (1.79e-2)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.91e-2)" "unprognostic (3.12e-3)" "unprognostic (6.73e-3)" "unprognostic (8.01e-3)" "unprognostic (4.16e-2)" "unprognostic (3.52e-3)" "unprognostic (5.99e-3)" "unprognostic (3.33e-1)" "prognostic unfavorable (5.67e-6)" "unprognostic (6.72e-2)" "unprognostic (6.22e-2)" "unprognostic (8.88e-2)" "unprognostic (1.03e-1)" 27.6 7.9 10.2 28.1 14.4 228.5 25.7 11.9 13.5 17.9 9.2 18.6 17.6 17.3 8.6 42.9 12.7 26.1 11.8 13.8 11.2 10.6 13.5 31.0 24.7 12.2 11.2 5.5 9.3 37.9 15.8 15.6 12.2 8.9 20.1 5.1 18.9 7.7 7.1 29.7 23.2 13.9 12.6 21.8 18.1 10.7 10.9 28.3 9.7 10.0 29.0 22.4 23.7 15.6 3.6 2.8 36.5 24.6 4.2 3.2 8.3 4.8 5.4 4.3 6.8 58.8 4.1 48.3 11.3 1.7 1.6 5.8 11.1 10.5 8.6 12.2 8.9 4.4 1.7 9.5 12.4 4.8 8.3 4.2 8.1 6.4 21.6 4.5 24.3 18.2 2.7 11.7 3.7 0.3 10.6 6.9 23.8 11.1 1.7 13.2 12.6 28.1 17.7 10.8 16.7 23.3 3.6 5.5 12.9 11.3 3.0 3.3 17.5 4.0 5.7 4.0 7.1 27.0 2.8 146.7 2.1 4.3 10.9 15.0 15.6 15.0 0.9 14.1 1.7 8.5 4.8 1.9 5.4 6.6 5.6 2.5 76.9 3.0 23.2 0.5 11.6 6.6 10.2 14.4 11.9 13.5 13.8 11.2 12.2 11.2 12.2 12.6 10.9 15.6 94.5 28.9 49.2 4.6 84.4 224.1 74.6 48.2 105.9 1.7 60.9 50.3 5.7 15.7 52.0 5.5 0.0 1.7 16.9 57.9 1.9 5.3 10.6 34.6 26.4 52.1 25.7 3.4 23.4 26.7 8.6 24.5 75.4 58.7 15.2 6.3 37.5 7.5 22.8 3.3 19.1 23.4 30.5 67.6 103.7 11.2 1.5 107.0 112.1 119.9 30.6 5.5 3.1 82.9 67.9 20.9 45.9 1.9 318.8 44.7 32.7 9.6 43.6 2.0 0.0 10.1 51.9 8.4 9.6 208.0 217.5 4.0 49.4 3.2 32.4 145.8 PGS1 DKFZP762M186 ENSG00000087157 "Phosphatidylglycerophosphate synthase 1" Q32NB8 17 78378649-78425114 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022526 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "HPA022526: AB_1855271" "unprognostic (1.19e-2)" "unprognostic (1.12e-1)" "unprognostic (3.48e-1)" "unprognostic (1.86e-3)" "unprognostic (1.35e-2)" "unprognostic (1.71e-2)" "prognostic unfavorable (1.37e-4)" "unprognostic (5.76e-3)" "unprognostic (3.17e-2)" "unprognostic (8.46e-3)" "prognostic favorable (7.33e-5)" "prognostic unfavorable (9.94e-4)" "prognostic unfavorable (1.16e-5)" "unprognostic (9.94e-2)" "unprognostic (5.60e-2)" "unprognostic (1.33e-1)" "unprognostic (2.72e-2)" 16.1 10.0 12.6 17.9 14.9 39.6 15.4 13.3 25.3 14.2 15.8 13.0 11.7 14.9 6.0 10.8 14.0 13.2 11.1 13.0 16.6 13.8 7.0 23.5 16.9 18.0 15.4 13.9 10.9 11.5 11.5 19.7 15.6 12.4 7.8 6.6 11.9 10.8 13.5 11.5 14.7 10.3 12.9 19.8 11.4 8.9 18.8 14.0 16.4 7.6 11.6 14.5 12.0 18.1 19.9 16.7 17.8 13.5 14.6 23.0 18.8 18.3 17.2 19.3 21.2 17.8 15.8 20.2 10.8 10.8 19.4 15.5 19.8 12.5 15.1 30.3 24.1 22.2 25.0 17.5 15.2 17.7 16.9 23.6 16.1 14.6 12.6 19.1 37.8 15.9 26.0 14.2 13.2 10.8 39.5 19.5 17.4 8.5 15.9 19.4 29.6 16.8 21.0 19.5 21.4 33.2 15.4 16.4 18.5 17.8 17.4 23.8 22.8 24.9 16.6 13.5 15.4 16.0 9.5 15.2 19.1 19.0 18.7 2.1 17.7 19.3 11.0 15.0 13.6 10.3 11.6 11.7 20.6 11.9 14.5 10.6 33.9 11.2 7.2 9.4 15.1 12.0 12.6 14.9 13.3 25.3 13.0 16.6 18.0 15.4 15.6 12.9 18.8 18.1 25.9 12.8 16.8 10.1 11.6 4.5 12.0 16.3 7.4 13.0 6.4 8.8 5.8 4.3 12.0 12.9 2.1 20.2 11.2 7.7 3.9 5.8 20.0 9.0 8.7 21.5 4.2 5.5 14.8 7.0 8.1 9.7 12.2 6.7 7.6 13.3 15.0 3.9 15.4 20.2 15.0 6.1 6.1 13.9 8.3 10.8 10.5 19.2 5.4 17.8 12.1 11.0 10.3 11.6 20.4 7.2 15.6 8.6 9.4 9.2 8.0 5.2 14.4 11.4 32.9 6.8 10.8 17.9 18.4 5.8 3.8 19.3 10.8 14.7 8.5 10.9 PIGA GPI3 ENSG00000165195 "Phosphatidylinositol glycan anchor biosynthesis class A" P37287 X 15319452-15335554 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 83.5;Suprabasal keratinocytes: 55.0;Urothelial cells: 62.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 22.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001174 Approved NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" "HPA001174: AB_2666220" "unprognostic (1.15e-1)" "unprognostic (1.04e-1)" "unprognostic (5.90e-2)" "unprognostic (7.92e-2)" "unprognostic (2.05e-1)" "unprognostic (2.16e-1)" "unprognostic (2.99e-3)" "unprognostic (2.24e-2)" "unprognostic (7.37e-3)" "unprognostic (3.93e-3)" "prognostic unfavorable (7.64e-4)" "unprognostic (1.85e-3)" "unprognostic (5.97e-3)" "unprognostic (2.24e-1)" "unprognostic (3.94e-1)" "unprognostic (2.12e-2)" "unprognostic (1.18e-2)" 2.1 2.9 2.2 2.9 2.7 9.2 3.1 2.0 3.6 2.8 0.8 3.7 1.9 3.0 3.5 5.1 2.8 3.7 2.0 1.6 1.8 3.8 4.5 6.7 3.5 2.8 2.7 2.4 4.0 3.3 0.6 3.6 2.2 2.7 3.7 4.5 4.6 1.7 1.3 1.4 2.4 2.5 2.2 2.0 2.8 2.6 2.3 4.0 4.4 1.3 4.7 10.3 1.9 5.8 14.5 8.3 9.1 5.0 2.6 2.8 7.0 3.7 5.7 7.4 7.3 9.2 6.5 6.6 2.9 2.9 9.0 5.8 14.3 11.4 12.6 6.1 9.5 5.5 11.0 5.8 4.5 8.8 2.9 3.3 8.1 10.0 16.0 2.4 5.0 5.2 6.4 7.0 5.1 9.2 9.0 3.4 4.7 5.5 8.2 3.0 12.4 10.7 5.6 9.4 6.2 9.4 6.9 6.8 14.4 8.7 6.6 7.4 4.2 6.2 2.4 14.0 7.3 5.4 7.2 9.9 9.4 5.6 7.9 22.9 3.8 4.3 2.6 6.3 3.7 3.0 4.1 2.6 3.9 2.1 3.8 2.9 5.2 1.8 8.6 2.6 4.1 2.7 2.2 2.7 2.0 3.6 1.6 1.8 2.8 2.7 2.2 2.2 2.3 5.8 6.4 19.2 83.5 6.8 7.2 29.6 41.9 10.6 13.6 3.5 13.2 10.5 6.9 5.7 20.1 3.7 0.0 6.3 7.4 8.4 11.7 7.6 5.4 30.8 9.8 7.9 10.7 9.3 2.2 5.8 10.2 12.7 17.9 45.6 33.6 3.0 3.6 4.4 8.8 3.3 2.0 5.0 2.0 8.4 43.4 4.4 3.1 18.1 28.4 2.8 3.6 4.2 4.1 1.0 7.7 8.3 5.1 3.0 5.5 32.0 2.1 6.6 19.8 3.0 13.1 10.6 16.3 2.7 3.7 35.5 55.0 28.0 11.7 2.9 6.0 62.2 PITPNC1 "RDGB-BETA, RDGBB, RDGBB1" ENSG00000154217 "Phosphatidylinositol transfer protein cytoplasmic 1" Q9UKF7 17 67377281-67697261 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 1255.9;Inhibitory neurons: 330.9;Oligodendrocyte precursor cells: 281.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA026563, HPA031250" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol Nucleoplasm "HPA026563: AB_1855409, HPA031250: AB_2673808" "unprognostic (1.33e-1)" "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "unprognostic (1.14e-3)" "unprognostic (4.17e-2)" "prognostic favorable (4.85e-5)" "unprognostic (6.57e-2)" "unprognostic (6.32e-3)" "unprognostic (1.23e-3)" "unprognostic (1.19e-1)" "unprognostic (5.70e-2)" "unprognostic (2.31e-2)" "unprognostic (1.34e-2)" "unprognostic (9.83e-2)" "unprognostic (7.88e-2)" "unprognostic (2.65e-3)" "unprognostic (1.16e-2)" 25.7 8.9 27.2 5.6 30.1 3.8 18.6 23.5 26.9 8.7 13.2 7.6 1.5 7.8 3.8 9.8 10.9 3.8 13.3 22.7 31.2 21.8 9.8 15.1 8.8 38.4 41.0 15.2 23.1 1.8 13.7 6.0 28.2 11.9 2.2 15.0 14.1 4.4 5.4 4.9 8.7 3.5 28.7 9.4 12.6 2.5 42.7 8.4 9.0 5.0 7.4 12.0 9.2 20.1 4.2 1.0 4.5 6.8 2.8 5.1 3.9 6.0 2.9 0.8 0.4 0.0 6.4 4.6 1.4 3.6 1.7 2.0 6.7 6.0 1.1 9.3 3.0 0.7 7.6 3.4 0.7 1.4 9.8 3.6 2.2 0.9 2.5 0.5 3.2 6.5 0.3 16.9 2.3 7.0 10.9 2.8 6.6 1.8 7.7 15.2 0.9 4.2 9.7 5.4 4.7 13.0 1.7 3.3 4.1 4.8 3.0 4.7 3.7 1.8 1.0 2.4 2.9 13.2 6.2 3.7 14.4 4.6 1.6 0.7 1.4 10.3 11.1 2.6 5.7 0.5 6.9 9.2 0.9 1.3 8.2 8.3 1.7 5.2 4.1 0.1 2.8 4.1 27.2 30.1 23.5 26.9 22.7 31.2 38.4 41.0 28.2 28.7 42.7 20.1 102.6 9.6 1.1 1255.9 9.6 5.4 55.6 4.6 8.0 15.2 7.7 4.1 6.9 21.5 4.6 0.0 2.1 7.9 84.0 5.8 21.5 43.3 0.2 13.7 5.7 59.8 6.0 4.0 88.4 49.1 13.6 18.9 8.2 30.9 5.1 7.7 21.4 10.1 13.8 74.0 330.9 1.3 4.1 21.4 22.3 1.4 5.0 17.7 10.6 103.0 20.2 34.6 84.5 281.5 9.7 38.7 4.4 14.7 28.0 32.9 0.1 21.2 3.4 21.8 26.3 66.5 25.7 0.4 3.8 9.0 4.3 3.4 75.7 2.7 3.8 54.3 PKP3 ENSG00000184363 "Plakophilin 3" Q9Y446 11 392614-404908 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 294.4;skin 1: 223.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 345.0;Extravillous trophoblasts: 176.8;Paneth cells: 248.9;Proximal enterocytes: 195.6;Undifferentiated cells: 142.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 151.3;CAPAN-2: 102.6;HaCaT: 199.1;hTCEpi: 126.9;MCF7: 94.9;SK-BR-3: 148.0" "Region enriched" "Detected in single" 37 "cerebellum: 8.9" "Low region specificity" "Detected in all" "CAB012993, HPA062937" Enhanced Enhanced "Nucleoplasm,Cell Junctions" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" Nucleoplasm "CAB012993: AB_2533221, HPA062937: AB_2684908" "unprognostic (4.74e-2)" "unprognostic (5.28e-2)" "unprognostic (4.45e-2)" "unprognostic (2.25e-2)" "unprognostic (1.58e-2)" "unprognostic (1.57e-1)" "unprognostic (8.88e-3)" "prognostic unfavorable (2.89e-5)" "unprognostic (1.25e-1)" "unprognostic (6.73e-3)" "prognostic unfavorable (3.93e-4)" "unprognostic (3.55e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.16e-2)" "unprognostic (3.41e-1)" "unprognostic (2.60e-1)" "unprognostic (3.15e-2)" 1.1 0.1 0.3 3.7 0.2 0.0 9.1 0.2 0.6 50.2 0.1 34.3 31.1 1.4 4.7 294.4 7.5 4.9 0.8 0.3 0.3 4.2 0.8 9.7 0.1 0.6 0.2 0.3 27.4 9.1 15.8 10.9 0.6 19.8 10.2 0.0 52.8 5.0 1.0 223.0 28.6 0.5 0.2 0.2 29.1 0.7 0.3 2.5 12.8 0.1 8.8 9.2 104.3 0.3 151.3 28.8 0.0 0.6 0.1 0.2 60.3 1.2 1.0 3.1 1.6 59.2 102.6 0.1 6.0 1.1 6.4 199.1 0.0 75.1 0.5 0.1 36.9 0.1 18.0 41.7 0.6 0.0 0.3 0.5 126.9 0.5 30.8 0.5 0.5 0.0 45.3 0.9 0.4 94.9 0.5 0.2 0.3 75.6 49.1 0.8 0.3 0.6 1.6 29.9 41.1 0.7 42.7 148.0 0.2 1.8 53.8 0.4 5.4 1.0 5.2 2.7 0.8 0.2 0.4 0.1 1.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.6 0.3 0.3 0.6 0.2 0.6 0.2 0.3 0.3 0.2 16.0 13.0 0.0 1.1 72.1 52.0 56.1 54.7 0.2 27.7 26.5 1.1 11.5 36.8 12.9 0.0 133.8 0.4 345.0 0.0 83.8 0.0 16.1 1.8 1.8 21.7 0.0 0.2 62.9 176.8 2.3 91.3 27.4 13.4 0.4 0.0 0.3 13.2 0.0 0.0 95.1 36.7 0.3 6.5 0.4 0.9 0.9 1.8 0.0 2.0 0.6 0.0 0.0 0.0 140.2 248.9 0.0 0.2 63.5 195.6 0.9 17.9 0.2 0.0 0.0 2.8 0.2 1.7 114.1 88.7 109.7 1.6 0.0 142.9 60.4 PLEKHG1 "ARHGEF41, KIAA1209" ENSG00000120278 "Pleckstrin homology and RhoGEF domain containing G1" Q9ULL1 6 150599883-150843665 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 31.2" "Cell type enhanced" "Detected in many" "Adipocytes: 91.2;Astrocytes: 98.6;Endothelial cells: 58.4;Microglial cells: 131.2;Oligodendrocytes: 168.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 31 "memory B-cell: 23.9;naive B-cell: 22.9" "Lineage enriched" "Detected in single" 31 "B-cells: 23.9" "Cell line enhanced" "Detected in many" "AF22: 17.6;HAP1: 26.4;Karpas-707: 23.4;U-698: 16.6" "Region enhanced" "Detected in all" "thalamus: 51.3" "Low region specificity" "Detected in all" "HPA027128, HPA027319, HPA028270" Approved Enhanced Nucleoplasm Yes No "Cluster 37: B-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA027128: AB_2672124, HPA027319: AB_10600306, HPA028270: AB_10611388" "unprognostic (2.93e-1)" "unprognostic (3.44e-1)" "unprognostic (3.04e-3)" "unprognostic (2.34e-1)" "unprognostic (1.05e-1)" "unprognostic (2.80e-3)" "unprognostic (1.85e-1)" "unprognostic (4.82e-2)" "unprognostic (2.10e-1)" "unprognostic (1.60e-1)" "unprognostic (3.47e-2)" "unprognostic (1.50e-1)" "unprognostic (4.62e-3)" "unprognostic (3.63e-1)" "unprognostic (4.30e-2)" "unprognostic (3.83e-1)" "unprognostic (2.15e-2)" 15.1 1.6 9.8 9.4 12.3 2.4 13.7 15.5 8.9 7.5 3.9 5.9 4.9 5.6 10.8 9.4 8.7 7.9 6.9 5.8 8.7 7.7 4.9 10.4 14.7 19.5 16.2 3.1 2.7 6.7 3.6 14.2 18.3 2.7 5.9 4.7 3.5 4.9 3.5 7.4 6.6 5.6 18.2 31.2 4.5 6.3 19.1 22.4 5.7 5.0 13.9 9.1 5.3 21.5 0.0 0.2 17.6 0.1 0.0 0.0 12.6 0.0 0.0 0.0 0.0 10.1 4.4 7.2 6.8 0.0 1.6 2.5 26.4 2.4 0.0 11.4 2.9 0.4 1.4 0.0 0.0 0.0 1.9 1.1 6.7 0.0 0.2 0.0 11.0 5.9 0.0 23.4 0.0 0.3 2.3 0.1 1.3 7.0 0.7 1.2 0.0 0.0 5.1 11.9 0.5 0.1 0.1 3.1 2.2 1.9 0.0 0.1 11.2 0.1 2.4 0.0 4.9 0.0 0.0 16.6 0.0 0.0 3.6 0.0 0.0 0.0 0.1 0.0 0.7 23.9 0.4 0.6 0.0 22.9 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.7 9.8 12.3 15.5 8.9 5.8 8.7 19.5 16.2 18.3 18.2 19.1 21.5 91.2 0.0 6.2 98.6 50.3 4.2 0.5 5.5 2.8 0.9 2.0 3.3 2.1 1.5 6.8 7.3 0.0 5.5 0.7 7.2 3.9 2.6 3.8 20.7 6.2 58.4 5.4 5.0 12.8 1.1 1.6 11.8 7.1 19.2 0.0 7.9 35.0 4.3 0.6 0.0 5.8 8.2 8.2 5.9 3.8 1.6 0.3 2.0 5.4 131.2 4.7 11.3 0.0 14.1 168.5 9.4 12.4 0.4 5.2 1.1 3.9 3.6 9.6 0.7 0.0 2.0 3.0 0.7 1.5 6.2 3.7 2.9 5.1 1.1 5.5 3.6 PLSCR1 MMTRA1B ENSG00000188313 "Phospholipid scramblase 1" O15162 3 146515180-146544856 "Predicted intracellular proteins, Transporters" "Antiviral defense, Host-virus interaction" "DNA-binding, Host cell receptor for virus entry, Hydrolase, Nuclease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 291.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 319.8;BJ hTERT+ SV40 Large T+ RasG12V: 418.6;HHSteC: 292.9;SK-MEL-30: 569.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068923, CAB070421" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Plasma membrane" "Golgi apparatus" "CAB070421: AB_11153452, HPA068923: AB_2686059" "unprognostic (7.88e-2)" "unprognostic (1.10e-1)" "unprognostic (5.34e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.12e-1)" "unprognostic (3.35e-1)" "unprognostic (5.22e-2)" "unprognostic (7.73e-3)" "unprognostic (9.19e-3)" "unprognostic (6.93e-3)" "unprognostic (3.07e-3)" "unprognostic (1.10e-1)" "unprognostic (1.09e-3)" "unprognostic (5.26e-2)" "unprognostic (1.64e-2)" "unprognostic (1.76e-1)" "unprognostic (1.63e-1)" 60.6 23.0 11.4 86.7 12.5 64.4 45.9 12.7 17.6 25.9 11.9 65.0 39.8 28.2 31.0 47.9 40.0 66.1 24.3 12.1 13.5 71.9 49.2 49.3 40.6 17.4 14.2 34.9 38.3 16.8 15.4 56.3 15.3 23.7 59.5 9.8 49.1 49.6 10.8 13.6 45.4 41.9 16.2 64.5 44.0 17.1 14.7 30.0 27.8 17.6 39.4 68.1 29.5 14.0 106.2 41.5 26.4 12.1 40.9 65.0 40.5 32.6 88.4 319.8 418.6 34.0 88.1 8.4 75.6 20.6 245.9 86.2 21.2 32.7 56.6 32.9 21.6 66.1 12.5 25.2 292.9 40.3 35.4 106.3 53.3 36.6 182.3 52.6 49.4 19.1 44.7 104.0 66.9 41.0 30.6 16.1 25.8 71.6 37.6 27.4 28.1 2.9 95.9 29.6 16.3 0.0 42.6 20.9 569.9 35.8 20.7 46.8 30.6 26.9 22.7 59.1 55.8 79.2 15.6 0.4 27.0 29.0 23.3 41.1 157.6 44.3 20.8 159.6 30.0 25.2 13.5 18.5 105.8 19.7 9.3 13.9 100.0 57.8 94.8 28.5 8.3 79.3 11.4 12.5 12.7 17.6 12.1 13.5 17.4 14.2 15.3 16.2 14.7 14.0 191.4 35.3 43.0 12.7 28.2 37.0 106.5 92.1 26.2 0.7 36.0 22.6 7.3 124.4 110.4 95.6 0.0 53.7 25.4 134.2 74.3 291.6 2.0 56.1 24.5 135.2 33.1 18.3 7.1 217.4 114.1 74.8 47.9 58.2 28.4 60.5 100.6 29.7 139.9 0.0 9.0 71.5 79.3 86.2 162.9 6.8 114.9 185.5 48.0 35.6 72.3 64.3 32.0 7.1 0.3 157.6 110.3 45.9 18.2 79.6 40.7 75.0 133.5 1.6 39.5 63.4 59.2 1.5 2.4 21.8 28.6 44.5 25.9 42.6 69.4 211.9 PLVAP "FELS, gp68, PV-1, PV1" ENSG00000130300 "Plasmalemma vesicle associated protein" Q9BX97 19 17351450-17377342 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 436.2" "Group enriched" "Detected in many" 4 "Adipocytes: 439.2;Endothelial cells: 344.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 35.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 35.2" "Cell line enriched" "Detected in some" 27 "EFO-21: 549.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002279 Supported Approved "Plasma membrane,Centrosome,Cytosol" NA NA 53000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Plasma membrane, Centrosome" "HPA002279: AB_1079636" "unprognostic (3.19e-1)" "unprognostic (8.22e-2)" "unprognostic (7.87e-2)" "unprognostic (2.38e-2)" "unprognostic (1.93e-2)" "unprognostic (2.49e-3)" "unprognostic (4.17e-3)" "unprognostic (1.01e-1)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.53e-2)" "unprognostic (8.96e-2)" "unprognostic (4.24e-3)" "unprognostic (4.70e-3)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (8.17e-2)" 283.0 51.1 2.7 54.6 3.1 1.7 210.5 2.9 4.2 102.7 18.2 95.7 86.7 90.0 5.1 48.9 83.3 139.2 92.5 3.3 3.1 153.0 6.9 31.0 50.5 3.7 3.5 16.7 96.1 98.6 64.3 48.8 3.6 68.4 22.3 0.0 77.9 38.0 32.7 58.9 103.3 50.5 3.6 166.7 116.6 4.4 3.5 18.9 436.2 12.9 16.2 104.4 80.8 4.1 0.3 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 549.1 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 9.5 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 1.1 20.0 0.0 2.3 0.1 0.3 0.5 2.2 2.5 0.0 0.2 0.0 0.0 0.2 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.7 35.2 0.0 0.6 2.7 3.1 2.9 4.2 3.3 3.1 3.7 3.5 3.6 3.6 3.5 4.1 439.2 6.4 0.0 0.3 0.7 22.9 1.0 0.0 8.0 0.0 2.7 3.3 3.7 0.0 0.0 0.0 0.0 0.1 5.1 0.0 0.0 1.7 3.6 0.4 0.3 344.9 0.0 0.4 0.4 2.5 0.1 48.9 0.0 0.3 0.0 0.4 79.6 0.2 1.8 0.0 0.3 0.0 0.0 3.5 28.8 0.8 0.0 5.5 23.2 6.5 0.0 0.5 0.0 0.0 0.3 0.1 0.0 0.0 7.6 1.5 0.0 0.0 0.0 0.1 0.0 1.4 6.1 0.5 0.7 2.9 16.8 0.1 1.4 0.7 0.0 2.3 PMAIP1 "APR, NOXA" ENSG00000141682 "Phorbol-12-myristate-13-acetate-induced protein 1" Q13794 18 59899996-59904305 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 88.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 803.1;Endometrial ciliated cells: 463.6;Glandular and luminal cells: 529.8;Squamous epithelial cells: 474.5;Suprabasal keratinocytes: 691.2;Urothelial cells: 569.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 169.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 169.8" "Cell line enhanced" "Detected in many" "GAMG: 207.5;U-138 MG: 202.1" HPA051063 Uncertain Uncertain Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Vesicles "HPA051063: AB_2681330" "unprognostic (1.35e-3)" "unprognostic (5.02e-2)" "unprognostic (5.57e-2)" "unprognostic (4.88e-2)" "unprognostic (6.65e-3)" "unprognostic (3.76e-2)" "unprognostic (2.00e-3)" "unprognostic (1.26e-2)" "unprognostic (4.41e-2)" "unprognostic (6.12e-2)" "unprognostic (8.47e-3)" "unprognostic (5.56e-2)" "prognostic unfavorable (3.15e-6)" "unprognostic (2.53e-1)" "unprognostic (7.68e-2)" "unprognostic (8.74e-2)" "unprognostic (1.09e-1)" 2.0 0.7 2.8 8.0 2.7 88.1 3.9 2.6 5.1 6.5 3.0 2.5 3.7 5.4 0.2 13.7 2.9 8.0 0.9 2.6 2.8 2.3 2.1 3.8 14.7 2.8 2.7 0.7 1.2 14.8 16.7 13.4 3.0 3.6 3.4 2.0 3.6 1.3 1.5 24.1 3.9 1.9 2.7 4.6 2.5 3.1 3.7 12.1 2.1 1.5 14.2 17.3 7.9 2.4 26.6 17.4 5.2 1.6 8.8 69.0 19.8 125.4 84.1 71.5 70.7 1.7 32.5 104.6 17.0 23.5 207.5 38.4 21.0 11.8 70.4 33.7 154.5 19.4 26.0 4.6 87.6 67.1 28.2 28.7 30.8 93.8 48.5 26.1 24.0 46.7 26.7 17.5 24.1 2.6 53.8 20.1 151.7 2.7 32.7 54.1 28.8 39.1 41.9 24.2 39.7 32.7 6.1 3.2 71.5 56.1 5.3 54.6 90.6 202.1 54.0 10.3 141.4 2.8 0.3 92.1 16.8 37.6 48.5 169.8 16.7 103.6 10.9 26.2 9.6 33.8 5.0 6.8 12.1 25.0 4.1 5.9 53.5 6.3 32.1 10.2 25.2 15.1 2.8 2.7 2.6 5.1 2.6 2.8 2.8 2.7 3.0 2.7 3.7 2.4 29.2 32.1 25.7 0.7 175.3 803.1 316.2 236.4 415.4 0.2 111.8 82.0 4.7 12.8 129.6 3.7 2.1 120.3 125.3 141.1 0.0 54.7 0.8 463.6 48.8 48.5 133.4 5.5 0.0 67.0 14.7 32.9 168.2 529.8 31.8 11.8 7.9 0.5 89.5 0.0 0.0 146.8 181.0 37.2 363.3 1.1 0.9 140.6 74.7 7.5 142.4 0.3 34.0 0.0 0.2 100.1 123.6 1.2 63.1 265.7 94.7 0.5 101.5 0.7 0.0 10.8 32.0 0.3 19.8 474.5 691.2 315.2 117.0 19.8 122.2 569.2 PRKCH "PKC-L, PKCL, PRKCL" ENSG00000027075 "Protein kinase C eta" P24723 14 61187559-61550976 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 128.4;Microglial cells: 267.9;NK-cells: 229.6;T-cells: 130.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "gdT-cell: 116.5;MAIT T-cell: 91.3;memory CD4 T-cell: 88.0;memory CD8 T-cell: 137.0;naive CD4 T-cell: 106.9;naive CD8 T-cell: 105.5;NK-cell: 117.1;T-reg: 79.8" "Group enriched" "Detected in all" 14 "NK-cells: 117.1;T-cells: 137.0" "Cell line enhanced" "Detected in many" "BEWO: 81.8;HUVEC TERT2: 108.7;MOLT-4: 75.8;RT4: 46.4;TIME: 72.0" "Group enriched" "Detected in all" 6 "basal ganglia: 28.0;thalamus: 17.9" "Low region specificity" "Detected in all" "HPA026294, HPA053709" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Plasma membrane" "HPA026294: AB_10603988, HPA053709: AB_2682237" "unprognostic (1.42e-1)" "unprognostic (3.89e-3)" "unprognostic (1.78e-1)" "unprognostic (1.96e-3)" "unprognostic (1.04e-1)" "prognostic favorable (8.55e-6)" "unprognostic (1.14e-2)" "unprognostic (2.97e-2)" "unprognostic (4.14e-1)" "unprognostic (1.94e-1)" "unprognostic (7.96e-2)" "unprognostic (1.60e-1)" "unprognostic (1.52e-3)" "unprognostic (1.13e-1)" "unprognostic (4.14e-2)" "unprognostic (6.98e-2)" "unprognostic (4.73e-3)" 26.6 7.8 21.1 21.9 30.2 24.2 21.9 12.4 15.7 20.6 9.5 8.9 9.5 14.5 10.9 30.0 13.6 19.7 19.2 13.2 13.9 14.5 10.3 35.3 55.2 19.3 21.7 5.9 8.4 14.2 15.0 32.5 19.4 15.8 8.8 3.1 28.3 11.4 14.2 23.7 16.6 18.1 18.6 38.5 9.6 7.5 29.9 65.8 21.1 18.1 38.5 25.3 21.7 15.5 18.1 6.3 0.8 4.9 2.8 0.6 81.8 0.3 1.5 0.8 0.8 1.9 10.5 0.3 12.4 0.1 1.6 12.3 0.6 13.5 1.4 2.2 7.9 0.1 2.0 0.7 1.2 0.0 2.4 2.2 13.8 0.7 9.4 1.2 108.7 35.4 0.2 0.4 6.2 32.7 75.8 0.7 1.4 12.9 8.4 6.3 3.2 0.2 0.2 46.4 3.2 5.1 2.1 16.2 10.2 14.5 15.9 1.4 72.0 2.1 14.0 2.1 0.9 1.4 0.2 0.6 3.1 1.1 3.6 0.8 3.0 2.4 116.5 1.9 91.3 2.2 88.0 137.0 9.2 1.4 106.9 105.5 5.9 117.1 1.1 3.0 79.8 84.0 21.1 30.2 12.4 15.7 13.2 13.9 19.3 21.7 19.4 18.6 29.9 15.5 59.7 6.4 11.4 2.0 6.6 18.7 16.4 8.3 15.9 0.4 15.0 9.3 9.0 10.0 15.5 0.0 0.0 27.6 128.4 0.6 3.9 6.0 32.6 10.3 2.1 70.8 11.9 18.1 1.7 6.8 21.2 5.0 7.1 20.9 1.3 15.4 68.9 2.0 6.0 0.0 3.1 2.7 2.0 14.4 6.9 6.0 1.8 15.4 16.0 267.9 8.9 7.0 229.6 4.5 1.8 5.4 4.3 6.8 26.6 14.7 4.6 1.2 9.2 0.5 0.0 4.4 5.2 0.1 2.4 18.1 26.7 48.3 130.5 1.6 1.3 26.0 PRKD2 "DKFZP586E0820, HSPC187, PKD2" ENSG00000105287 "Protein kinase D2" Q9BZL6 19 46674275-46717127 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Cell adhesion, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-266/84: 149.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021490, HPA056727" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 57: B-cells - Immune response" Nucleoplasm Cytosol "HPA021490: AB_1855708, HPA056727: AB_2683217" "unprognostic (3.01e-2)" "unprognostic (1.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.06e-2)" "unprognostic (8.91e-2)" "unprognostic (1.99e-2)" "unprognostic (8.79e-3)" "unprognostic (2.61e-1)" "unprognostic (6.22e-2)" "unprognostic (4.21e-3)" "unprognostic (8.89e-2)" "unprognostic (2.74e-1)" "unprognostic (3.45e-3)" "unprognostic (1.04e-2)" "unprognostic (7.19e-2)" "unprognostic (4.34e-2)" "prognostic favorable (9.15e-4)" 29.0 11.5 7.2 23.6 7.3 29.4 29.3 5.4 7.7 26.6 12.5 20.3 17.1 21.8 4.7 27.5 24.1 11.2 13.8 6.1 6.0 19.2 13.8 34.3 31.1 10.0 6.3 21.8 19.1 8.3 24.0 11.1 6.8 23.9 7.1 4.4 24.7 10.0 8.0 46.8 29.9 6.0 6.0 54.3 20.3 6.6 7.7 25.6 28.9 4.8 21.2 19.5 26.9 6.6 19.6 34.5 12.8 16.6 7.3 6.4 15.1 11.5 13.2 19.6 19.7 19.7 21.0 22.3 16.3 13.2 13.2 27.5 9.5 26.0 5.9 19.8 17.5 25.9 11.5 10.2 12.8 21.2 34.7 11.0 15.8 12.7 9.8 12.8 30.1 21.5 14.6 35.4 7.0 23.8 32.7 53.1 9.7 27.4 17.4 25.8 5.8 37.5 11.4 32.7 7.7 22.4 18.8 18.8 4.6 10.6 11.6 7.5 17.6 8.7 18.8 7.1 10.0 31.8 149.1 13.5 8.5 17.7 11.0 0.6 0.7 2.6 3.9 0.7 3.3 4.3 3.9 4.3 0.3 4.1 3.3 3.3 5.3 2.2 0.5 0.0 2.9 1.5 7.2 7.3 5.4 7.7 6.1 6.0 10.0 6.3 6.8 6.0 7.7 6.6 37.8 9.6 9.9 5.9 46.5 22.0 32.0 13.2 22.8 6.4 13.9 11.3 17.2 12.8 13.0 9.2 0.0 13.8 17.5 43.6 7.9 18.6 1.2 15.3 6.7 37.2 21.6 4.0 6.5 28.2 13.8 9.6 23.4 15.0 14.5 14.1 37.1 8.5 9.0 1.7 2.8 21.7 4.1 12.3 11.4 3.1 11.8 8.3 12.4 11.2 9.3 6.5 42.2 4.0 3.1 29.5 35.1 6.8 47.0 22.9 34.1 9.3 15.6 4.4 13.1 6.1 7.6 2.9 17.9 21.2 26.7 29.7 31.9 6.6 15.3 30.2 PRSS22 "BSSP-4, hBSSP-4, SP001LA" ENSG00000005001 "Serine protease 22" Q9GZN4 16 2852730-2858170 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 79.6;salivary gland: 26.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 221.0;Club cells: 343.9;Ionocytes: 207.5;Pancreatic endocrine cells: 380.6;Urothelial cells: 479.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CAPAN-2: 17.3;MCF7: 14.6;RT4: 10.4;SK-BR-3: 22.9" "Region enhanced" "Detected in some" "cerebral cortex: 2.6" "Low region specificity" "Detected in all" HPA049161 Approved Approved Nucleoplasm "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA049161: AB_2680660" "unprognostic (1.45e-1)" "unprognostic (9.80e-2)" "unprognostic (3.50e-2)" "unprognostic (4.48e-1)" "unprognostic (2.29e-4)" "unprognostic (2.58e-1)" "unprognostic (4.42e-2)" "unprognostic (1.52e-2)" "unprognostic (5.06e-1)" "unprognostic (7.52e-2)" "unprognostic (3.74e-3)" "unprognostic (4.12e-1)" "unprognostic (2.32e-4)" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (2.75e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 23.4 0.0 0.5 0.3 0.7 0.4 79.6 1.3 0.8 0.0 0.0 0.0 16.7 0.5 2.9 0.0 0.0 0.0 0.0 5.8 1.5 2.4 1.1 0.0 6.0 0.5 0.0 26.9 0.3 0.0 3.2 0.2 0.0 0.0 0.0 5.4 0.0 0.0 0.0 1.3 0.0 2.2 2.5 23.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.3 17.3 0.0 0.0 0.0 0.0 1.8 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 22.9 0.0 0.0 2.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.2 4.2 0.0 0.2 23.2 221.0 128.8 28.5 0.0 42.8 23.7 0.3 38.6 343.9 16.5 0.0 36.7 1.9 18.5 1.9 113.1 0.0 28.4 4.6 1.8 3.6 0.0 0.0 98.3 37.1 1.3 52.5 56.6 0.0 0.0 0.0 0.1 2.3 0.0 0.0 7.5 207.5 0.0 1.4 0.0 0.0 0.9 7.2 0.0 1.0 0.0 0.0 0.0 0.0 380.6 32.3 0.0 0.3 75.4 0.6 0.2 108.0 0.0 0.0 0.0 13.7 0.1 0.2 22.7 27.6 10.5 2.7 0.0 6.9 479.5 PTPN12 "PTP-PEST, PTPG1" ENSG00000127947 "Protein tyrosine phosphatase non-receptor type 12" Q05209 7 77537295-77640069 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007097 Approved Approved "Plasma membrane,Cytosol" NA NA 770000 "Cluster 40: NK-cells - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Cytosol" "HPA007097: AB_1079689" "unprognostic (2.28e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.35e-1)" "unprognostic (3.35e-2)" "unprognostic (1.40e-3)" "unprognostic (4.48e-3)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.29e-1)" "unprognostic (5.83e-2)" "unprognostic (2.64e-1)" "prognostic unfavorable (2.01e-4)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.27e-6)" "unprognostic (4.99e-2)" "unprognostic (2.97e-1)" "unprognostic (1.81e-1)" "unprognostic (3.21e-1)" 60.5 30.1 24.2 43.9 26.6 69.9 50.3 29.2 31.6 40.9 25.9 48.9 18.9 38.6 18.6 38.5 39.6 40.2 39.0 25.1 27.3 36.1 30.9 65.0 27.5 28.5 27.8 34.6 20.1 21.0 21.9 74.7 30.5 26.4 27.7 30.9 23.8 33.2 24.6 36.9 29.7 40.2 26.7 52.7 27.1 30.1 32.7 33.9 31.0 44.5 27.5 46.7 39.6 30.2 72.4 43.5 100.6 51.8 69.1 71.7 54.2 73.3 93.0 56.6 80.0 21.6 109.9 8.6 23.2 86.3 123.6 50.2 34.2 73.4 113.3 21.2 19.2 44.9 44.2 88.4 67.7 25.8 28.8 59.0 80.3 123.2 157.6 101.0 121.6 2.1 54.9 12.2 182.6 49.4 3.6 71.9 81.7 97.6 49.2 15.1 80.6 4.5 97.6 38.5 12.5 66.6 90.4 81.5 73.4 172.2 39.5 93.9 89.3 121.4 73.1 45.0 141.3 12.6 7.4 22.2 71.6 65.9 215.7 3.6 4.1 6.8 3.1 2.8 1.3 2.3 1.1 2.6 3.8 1.0 0.6 3.3 9.5 13.3 5.3 0.3 1.6 2.7 24.2 26.6 29.2 31.6 25.1 27.3 28.5 27.8 30.5 26.7 32.7 30.2 139.3 70.5 56.2 30.0 18.2 68.8 60.0 55.9 23.9 16.7 40.9 26.3 41.3 28.6 46.4 20.2 8.4 40.0 89.0 31.2 3.9 42.1 3.5 43.9 62.4 114.4 12.1 16.6 65.8 39.6 58.7 54.6 21.4 87.2 14.5 21.7 119.2 24.6 50.1 35.3 58.0 21.7 28.5 82.0 121.3 6.7 46.6 96.1 35.6 93.7 54.9 66.9 163.7 70.4 67.3 75.0 21.4 47.0 17.6 62.0 10.9 19.2 23.2 15.2 65.7 127.9 66.8 51.2 71.4 29.8 101.4 72.1 27.3 24.4 23.3 104.8 PTPRB PTPB ENSG00000127329 "Protein tyrosine phosphatase receptor type B" P23467 12 70515870-70637440 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 215.9;Endothelial cells: 211.5;Hepatic stellate cells: 504.0;Microglial cells: 164.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 24.3;hTERT-RPE1: 19.7;HUVEC TERT2: 61.4;TIME: 90.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004782, HPA067868" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA 14000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cell Junctions" "CAB004782: , HPA067868: AB_2685911" "unprognostic (3.18e-1)" "unprognostic (2.99e-6)" "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (3.55e-2)" "unprognostic (1.77e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.91e-2)" "unprognostic (7.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" 26.7 9.4 16.0 4.7 14.1 0.1 18.8 12.3 12.1 12.8 7.1 10.9 7.5 12.3 4.4 6.8 10.8 14.7 23.2 10.1 12.4 22.5 16.7 35.7 3.2 15.9 14.2 4.0 6.2 7.8 4.7 32.6 18.1 6.3 11.1 1.4 3.3 8.0 17.1 4.1 9.3 18.1 12.4 30.0 6.2 2.5 19.0 3.0 14.8 38.8 3.4 7.7 5.3 11.9 4.4 0.3 1.9 0.2 0.0 0.1 0.9 0.9 4.2 2.2 5.2 0.1 3.4 1.7 24.3 0.6 0.4 15.2 0.2 0.7 7.8 1.3 0.7 0.4 1.7 1.1 0.2 0.7 0.0 0.1 0.7 6.1 0.0 19.7 61.4 0.0 3.6 1.0 1.3 0.0 0.1 0.0 2.3 4.4 0.9 0.1 1.6 0.9 11.3 1.8 0.0 0.8 1.6 0.0 3.5 0.4 0.0 1.5 90.3 0.9 0.9 0.4 5.4 1.1 0.9 0.8 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.0 14.1 12.3 12.1 10.1 12.4 15.9 14.2 18.1 12.4 19.0 11.9 215.9 0.0 13.2 2.0 3.1 3.7 0.8 1.0 0.0 7.1 0.9 0.9 12.3 11.5 1.3 3.7 0.0 0.0 2.0 12.8 0.0 1.5 4.6 2.2 0.7 211.5 0.0 16.0 52.5 0.9 0.0 7.3 1.5 4.0 25.2 0.5 504.0 4.7 0.4 5.0 68.8 6.4 0.0 20.0 4.6 3.0 1.2 1.2 5.4 164.9 0.0 0.4 0.0 2.5 2.9 12.2 11.1 0.0 0.1 0.8 3.2 0.1 0.2 0.9 0.0 6.4 5.2 0.7 0.7 0.9 1.6 0.0 1.0 1.8 6.8 0.7 PXN ENSG00000089159 Paxillin P49023 12 120210439-120265771 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 152.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 169.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003841, HPA051309" Supported Enhanced "Focal adhesion sites,Centrosome,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Focal adhesion sites" "Centrosome, Cytosol" "CAB003841: AB_562188, HPA051309: AB_2681436" "unprognostic (4.00e-2)" "unprognostic (1.94e-2)" "unprognostic (3.51e-2)" "unprognostic (3.55e-3)" "prognostic unfavorable (1.09e-4)" "prognostic unfavorable (3.72e-5)" "prognostic unfavorable (7.12e-5)" "prognostic unfavorable (1.73e-4)" "unprognostic (3.12e-2)" "unprognostic (9.19e-3)" "unprognostic (2.66e-2)" "unprognostic (1.73e-1)" "unprognostic (2.12e-2)" "unprognostic (3.35e-2)" "unprognostic (2.09e-1)" "unprognostic (1.98e-1)" "unprognostic (2.75e-2)" 83.1 60.9 28.7 49.1 30.8 81.4 74.4 27.6 30.5 64.5 33.7 69.0 55.7 56.3 18.7 30.9 72.3 38.2 84.2 28.0 28.5 70.2 29.5 84.6 29.3 37.1 30.8 28.5 34.5 27.8 29.5 73.3 30.3 58.9 49.9 61.8 49.4 40.6 119.2 45.6 61.1 44.5 31.8 72.5 47.5 26.5 36.6 25.9 58.1 46.1 18.4 75.8 53.2 29.2 182.4 87.5 31.3 30.1 60.4 158.1 206.1 151.8 128.6 118.9 61.5 102.5 108.9 12.2 94.6 154.9 115.1 126.0 21.7 272.0 93.0 9.9 18.6 2.3 63.8 37.9 86.8 2.7 3.6 76.5 176.2 125.3 143.9 139.7 211.6 32.2 32.4 19.5 239.3 119.6 11.1 4.1 43.5 77.1 300.8 26.2 51.0 10.8 121.4 171.9 48.7 14.5 133.2 40.3 81.7 72.1 96.1 14.8 289.9 78.9 86.7 103.6 183.9 20.4 12.3 4.6 228.9 27.0 159.2 40.8 44.2 49.2 84.5 15.7 45.3 1.7 38.4 56.0 26.2 1.1 29.5 40.3 169.6 51.8 0.8 4.1 31.4 60.6 28.7 30.8 27.6 30.5 28.0 28.5 37.1 30.8 30.3 31.8 36.6 29.2 93.6 57.7 27.9 11.8 3.0 42.3 40.6 32.8 15.4 7.8 20.3 22.9 14.7 22.8 33.3 42.3 33.3 40.8 61.6 83.1 19.6 31.6 2.1 26.0 16.7 71.0 54.6 6.1 5.1 40.2 152.4 29.7 37.2 28.8 18.3 6.2 62.2 17.2 34.2 11.8 7.7 52.7 24.4 42.3 23.7 2.8 24.2 23.5 26.6 19.7 36.8 9.1 99.9 13.0 9.2 84.8 51.6 18.8 14.5 41.7 56.6 14.6 40.0 33.6 6.6 16.7 12.1 3.5 9.1 8.1 19.5 25.0 34.4 11.3 35.8 42.6 RAB27A "GS2, HsT18676, RAB27, RAM" ENSG00000069974 "RAB27A, member RAS oncogene family" P51159 15 55202966-55319113 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Exocytosis Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 119.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 147.1;Intestinal goblet cells: 252.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 261.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 208.7;K-562: 238.0;Karpas-707: 179.4;SK-MEL-30: 188.3;U-937: 185.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001333, CAB034046" Enhanced NA NA "Cluster 46: Basophils - DNA binding" "Cluster 37: Intestine - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 27: Mucus-secreting cells - Mucin production" "CAB034046: AB_2176724, HPA001333: AB_1079730" "prognostic favorable (2.56e-4)" "unprognostic (9.75e-2)" "unprognostic (2.01e-2)" "unprognostic (1.81e-1)" "unprognostic (1.08e-1)" "unprognostic (1.79e-1)" "unprognostic (1.73e-1)" "unprognostic (2.32e-1)" "unprognostic (2.62e-1)" "unprognostic (2.77e-1)" "unprognostic (6.24e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (1.67e-4)" "unprognostic (4.23e-2)" "unprognostic (4.34e-1)" "unprognostic (7.95e-3)" "unprognostic (4.32e-1)" 17.5 27.8 3.5 40.2 3.9 100.2 13.9 4.4 4.4 12.9 5.6 53.0 30.0 12.8 5.0 20.6 12.3 17.6 7.7 3.4 6.7 19.2 43.6 42.4 46.0 5.8 5.0 8.0 29.2 11.4 31.4 17.6 5.9 61.2 66.1 4.2 18.3 11.8 3.2 12.8 40.9 25.8 5.0 30.8 119.9 10.0 5.9 19.3 30.5 7.0 46.2 37.5 13.9 5.7 23.0 10.0 9.7 11.3 8.3 38.8 9.5 29.4 32.5 19.2 26.4 7.0 15.6 0.9 22.3 16.0 38.9 16.0 15.7 27.0 18.3 84.9 9.7 5.4 37.6 18.1 56.0 208.7 26.5 34.3 44.2 29.0 71.6 80.7 46.9 26.4 238.0 179.4 20.7 27.7 1.5 57.6 3.6 38.9 14.7 32.4 27.3 50.3 28.7 17.7 14.9 7.1 31.4 15.2 188.3 24.3 13.3 162.2 25.3 52.5 20.3 33.1 33.6 72.0 88.2 6.0 70.2 185.1 19.0 261.3 72.4 99.8 59.2 30.1 58.2 8.0 28.6 61.9 39.0 13.4 13.9 37.4 114.9 34.1 24.0 2.1 36.2 48.9 3.5 3.9 4.4 4.4 3.4 6.7 5.8 5.0 5.9 5.0 5.9 5.7 27.5 76.9 147.1 12.7 18.6 14.1 25.7 19.2 6.2 3.0 16.3 18.3 7.4 15.7 50.1 11.0 2.1 6.3 81.0 18.5 13.7 24.6 2.8 10.1 15.6 32.1 74.3 12.8 12.5 87.6 18.7 16.9 93.3 16.7 31.7 8.8 41.7 41.7 15.6 0.0 12.2 252.0 12.2 33.3 15.2 2.2 7.5 31.1 71.2 10.3 71.9 2.4 104.0 10.1 7.1 62.9 15.9 13.9 38.6 32.3 14.6 6.7 31.3 4.4 19.7 9.4 15.8 9.3 4.6 7.1 15.5 7.5 81.4 4.6 18.4 23.4 RAMP3 ENSG00000122679 "Receptor activity modifying protein 3" O60896 7 45157791-45186302 "FDA approved drug targets, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 144.6" "Group enriched" "Detected in many" 12 "Adipocytes: 287.8;Endothelial cells: 366.0;Hepatic stellate cells: 555.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "Karpas-707: 2.5" "Group enriched" "Detected in all" 4 "cerebellum: 62.2;cerebral cortex: 49.2;thalamus: 174.9;white matter: 60.0" "Low region specificity" "Detected in all" HPA075527 Supported "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA075527: " "unprognostic (1.62e-3)" "prognostic favorable (2.89e-4)" "unprognostic (4.85e-2)" "unprognostic (6.88e-3)" "unprognostic (3.68e-2)" "unprognostic (1.44e-3)" "prognostic favorable (2.50e-6)" "unprognostic (1.14e-1)" "unprognostic (2.35e-1)" "unprognostic (3.19e-1)" "unprognostic (2.79e-2)" "unprognostic (9.49e-2)" "unprognostic (1.09e-2)" "unprognostic (1.20e-2)" "unprognostic (2.43e-1)" "unprognostic (1.91e-1)" "unprognostic (9.21e-2)" 86.9 32.6 17.7 23.0 19.7 0.2 71.7 26.9 22.7 33.5 21.3 24.4 10.2 25.9 3.9 18.9 22.8 28.7 91.3 19.2 25.8 84.1 23.9 144.6 55.0 37.3 25.7 7.4 19.7 28.1 22.3 8.6 34.2 29.7 8.6 1.1 22.1 12.9 19.3 22.8 30.0 24.4 31.6 11.4 25.7 6.3 23.5 7.3 71.9 26.9 30.3 28.5 30.5 42.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 17.7 19.7 26.9 22.7 19.2 25.8 37.3 25.7 34.2 31.6 23.5 42.4 287.8 0.0 1.9 0.3 3.6 16.3 0.3 0.0 2.2 0.6 5.9 2.8 8.7 1.5 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.1 20.8 0.4 7.3 366.0 0.0 13.5 3.5 0.7 0.1 10.7 0.0 0.2 0.0 0.0 555.4 7.3 0.5 0.0 0.2 0.0 0.0 31.2 19.1 6.7 1.2 1.3 26.6 5.6 0.0 0.2 0.0 0.0 6.5 0.0 0.0 1.2 1.3 0.6 0.0 0.0 0.0 0.5 0.0 2.8 4.9 0.3 0.9 0.9 14.5 0.0 1.7 1.5 0.0 0.5 RAPGEF5 "GFR, KIAA0277, MR-GEF" ENSG00000136237 "Rap guanine nucleotide exchange factor 5" Q92565 7 22118236-22357154 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 152.1;parathyroid gland: 387.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 504.6;Inhibitory neurons: 193.4;Microglial cells: 138.7;Oligodendrocytes: 640.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 21.1;HUVEC TERT2: 45.0;SCLC-21H: 34.1;TIME: 25.8;U-698: 37.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057821, HPA076772" Uncertain Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Nuclear bodies" "HPA057821: AB_2683538, HPA076772: AB_2686814" "unprognostic (1.00e-1)" "unprognostic (1.57e-1)" "unprognostic (3.17e-2)" "prognostic unfavorable (9.44e-4)" "unprognostic (5.22e-2)" "prognostic favorable (3.52e-5)" "unprognostic (1.16e-1)" "unprognostic (2.10e-2)" "unprognostic (1.64e-1)" "unprognostic (2.10e-1)" "unprognostic (1.97e-1)" "unprognostic (1.31e-1)" "unprognostic (3.76e-2)" "unprognostic (6.36e-3)" "unprognostic (6.57e-2)" "unprognostic (2.55e-1)" "unprognostic (8.26e-3)" 21.0 12.7 30.7 7.0 82.9 0.9 16.4 76.1 58.5 8.9 2.9 9.5 7.5 8.8 4.8 13.9 8.3 16.8 16.8 45.7 46.9 16.7 21.8 37.5 14.3 115.3 71.8 6.5 20.1 387.8 7.4 67.2 107.1 5.1 11.0 4.2 7.6 5.7 5.1 9.2 8.3 12.1 82.0 50.9 7.0 6.4 59.8 15.7 11.7 11.1 10.7 9.3 11.9 152.1 2.8 0.0 4.6 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.0 5.5 1.4 21.1 1.1 0.3 0.7 13.0 2.8 1.9 0.0 0.0 4.2 0.3 0.0 5.4 0.1 0.0 0.1 0.5 2.4 1.3 0.7 0.7 45.0 5.9 4.8 0.1 0.0 1.2 3.0 0.1 3.6 5.4 4.0 5.2 0.0 7.4 4.2 1.9 34.1 9.0 0.5 6.0 0.1 0.7 3.0 0.1 25.8 0.0 1.0 0.4 1.1 10.9 2.5 37.4 0.5 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.7 82.9 76.1 58.5 45.7 46.9 115.3 71.8 107.1 82.0 59.8 152.1 125.5 9.6 16.5 13.4 3.1 11.0 4.2 2.4 86.0 30.6 8.8 5.5 10.0 15.7 3.8 0.0 0.0 0.3 0.6 16.0 1.9 6.5 61.5 3.3 1.2 70.1 7.2 0.4 504.6 7.0 0.1 5.3 16.3 10.8 8.2 0.1 86.0 6.3 0.2 23.5 193.4 18.3 2.0 3.1 2.0 65.2 1.8 0.9 7.2 138.7 0.0 0.6 0.0 28.1 640.8 5.0 20.3 4.9 12.9 3.0 18.1 0.3 0.5 1.6 85.5 1.4 21.5 1.2 1.6 19.8 11.2 0.3 2.4 1.9 10.1 4.4 RASGRP3 "CalDAG-GEFIII, GRP3, KIAA0846" ENSG00000152689 "RAS guanyl releasing protein 3" Q8IV61 2 33436324-33564750 "Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.4;skeletal muscle: 42.0" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 186.5;Plasma cells: 64.8;Urothelial cells: 106.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 13.9;memory B-cell: 12.3;naive B-cell: 15.2" "Group enriched" "Detected in many" 16 "B-cells: 15.2;granulocytes: 13.9" "Group enriched" "Detected in many" 7 "Daudi: 88.7;HEL: 92.0;U-266/70: 143.5;U-266/84: 59.1;U-698: 38.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058937 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 29: U-266 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Golgi apparatus" "HPA058937: AB_2683858" "unprognostic (2.64e-1)" "unprognostic (9.50e-2)" "unprognostic (1.45e-1)" "unprognostic (5.76e-3)" "unprognostic (1.05e-1)" "unprognostic (1.09e-2)" "unprognostic (3.90e-1)" "unprognostic (7.57e-2)" "unprognostic (2.39e-2)" "unprognostic (4.35e-2)" "unprognostic (2.43e-1)" "unprognostic (1.48e-1)" "unprognostic (9.96e-3)" "unprognostic (1.83e-2)" "unprognostic (2.93e-2)" "unprognostic (2.87e-1)" "unprognostic (5.82e-2)" 7.8 2.9 17.7 15.1 35.2 4.8 5.3 29.8 21.6 3.7 10.2 4.7 7.3 2.5 1.1 2.4 2.5 6.5 34.2 15.1 20.2 6.5 5.5 7.7 27.9 37.4 27.1 1.0 3.4 6.8 2.4 11.0 34.6 1.6 6.6 1.0 6.1 2.0 42.0 1.8 4.7 4.7 25.0 14.8 7.4 0.9 30.7 4.2 6.7 17.6 33.6 6.7 1.2 56.4 0.1 0.0 0.0 0.0 0.0 0.5 0.2 1.2 0.7 4.3 12.4 2.3 0.5 88.7 0.4 0.7 1.0 0.1 0.0 0.0 1.1 9.0 0.8 92.0 0.6 0.0 1.3 0.4 12.4 0.1 0.0 0.1 0.2 1.8 5.3 0.8 0.3 4.8 2.0 0.0 0.7 7.2 0.4 0.5 0.1 0.2 4.1 0.1 1.0 5.3 0.6 0.0 0.0 0.3 4.6 0.1 0.1 0.4 1.7 0.3 0.3 0.4 0.8 143.5 59.1 38.7 0.2 0.4 0.3 13.9 0.0 0.0 0.3 0.0 0.4 12.3 0.6 0.6 0.3 15.2 0.9 0.2 0.0 0.3 0.1 0.0 0.8 1.1 17.7 35.2 29.8 21.6 15.1 20.2 37.4 27.1 34.6 25.0 30.7 56.4 41.4 0.0 5.8 2.0 46.7 5.4 31.2 0.9 0.0 1.6 4.8 2.8 50.8 1.5 3.7 5.5 0.0 0.5 3.6 1.1 11.7 21.1 1.6 10.0 3.9 57.9 0.0 7.4 4.9 54.6 1.3 4.4 3.6 31.0 17.8 2.4 60.7 6.0 44.5 0.0 3.5 0.0 2.0 9.4 26.1 0.8 0.9 29.1 40.9 34.7 13.8 0.2 0.0 2.5 186.5 44.8 0.1 1.9 64.8 37.0 0.2 14.3 3.9 1.3 0.0 5.5 4.1 1.4 2.1 0.4 3.7 0.5 8.1 3.8 0.4 106.4 RBBP8 "COM1, CtIP, RIM, SCKL2" ENSG00000101773 "RB binding protein 8, endonuclease" Q99708 18 22798261-23026488 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 125.9;Spermatocytes: 116.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 36.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039890, HPA052946" Approved Supported Nucleoplasm NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" Nucleoplasm "HPA039890: AB_10794756, HPA052946: AB_2681996" "unprognostic (1.55e-3)" "unprognostic (4.10e-3)" "unprognostic (7.89e-2)" "unprognostic (1.01e-1)" "unprognostic (2.44e-1)" "unprognostic (7.28e-2)" "unprognostic (3.60e-3)" "unprognostic (1.87e-1)" "prognostic unfavorable (7.21e-4)" "unprognostic (2.29e-2)" "unprognostic (1.58e-3)" "unprognostic (1.04e-2)" "prognostic favorable (1.71e-5)" "unprognostic (3.91e-3)" "unprognostic (2.42e-2)" "unprognostic (1.01e-2)" "unprognostic (4.48e-1)" 10.1 8.7 6.8 10.0 6.8 18.2 29.4 9.2 11.3 20.9 41.6 14.5 9.3 20.1 23.4 22.1 28.0 12.7 7.0 7.4 9.2 42.2 14.4 13.5 14.0 6.3 7.3 6.4 18.5 22.1 17.5 8.5 6.4 10.8 12.9 6.2 19.5 23.3 2.3 28.5 12.9 16.4 6.2 7.6 13.1 28.7 8.5 32.4 18.2 3.5 17.3 18.3 18.0 7.3 32.9 24.8 36.0 41.9 18.2 19.4 28.2 44.2 31.1 40.3 56.5 45.7 36.3 95.4 19.9 27.9 38.5 67.3 41.2 89.9 78.5 68.3 33.2 41.8 32.0 44.0 22.2 151.5 43.7 13.9 86.0 61.0 105.3 23.6 16.6 65.7 25.0 69.2 41.6 49.1 112.8 50.6 34.2 60.1 41.5 57.6 65.9 58.9 117.4 34.7 84.1 39.8 74.1 22.4 39.0 20.5 129.1 39.4 12.0 107.2 49.3 52.4 78.0 92.9 108.4 105.3 49.1 72.2 58.8 17.0 6.5 3.9 1.2 24.0 0.5 6.6 1.7 2.1 8.2 5.3 0.9 1.5 2.4 7.9 36.7 8.1 4.7 3.8 6.8 6.8 9.2 11.3 7.4 9.2 6.3 7.3 6.4 6.2 8.5 7.3 13.1 35.3 42.8 10.1 22.9 27.4 44.7 125.9 76.8 4.3 22.6 72.6 10.4 35.8 41.9 29.5 4.2 12.7 25.0 14.5 43.0 30.5 17.7 56.0 19.5 14.2 7.7 37.0 20.3 33.0 9.4 13.2 23.0 67.3 66.1 22.3 5.7 16.4 11.7 1.7 15.5 9.3 16.2 11.4 23.5 14.5 6.5 27.5 23.2 8.4 9.0 2.1 4.1 9.5 2.7 44.9 8.6 5.3 53.8 37.5 17.5 26.1 28.2 7.9 0.0 20.4 14.0 116.6 83.4 36.2 19.7 15.2 13.6 9.8 14.9 45.5 RBM11 ENSG00000185272 "RNA binding motif protein 11" P57052 21 14216130-14228372 "Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "epididymis: 45.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 15.6;Excitatory neurons: 13.0;Inhibitory neurons: 14.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.2" "Lineage enriched" "Detected in single" 10 "T-cells: 1.2" "Cell line enhanced" "Detected in some" "HEL: 1.4;REH: 1.0;SuSa: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA045885 Supported Nucleoplasm NA NA "Cluster 32: T-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA045885: AB_10963937" "unprognostic (1.95e-2)" "unprognostic (1.35e-1)" "unprognostic (3.57e-1)" "unprognostic (5.44e-4)" "unprognostic (2.18e-1)" "unprognostic (7.97e-2)" "unprognostic (3.89e-1)" "unprognostic (1.38e-1)" "unprognostic (1.41e-1)" "unprognostic (3.23e-2)" "unprognostic (9.92e-4)" "unprognostic (5.74e-2)" "unprognostic (1.16e-4)" "unprognostic (3.45e-2)" "unprognostic (4.81e-2)" "unprognostic (2.69e-1)" "unprognostic (9.24e-3)" 0.2 0.7 2.4 0.3 2.1 0.5 0.4 1.8 2.9 0.3 1.5 0.3 0.2 0.7 45.2 0.6 0.9 0.2 0.6 2.2 2.2 1.2 0.0 0.3 0.3 2.2 2.4 2.0 0.3 1.2 1.6 0.1 2.5 0.5 0.1 2.4 0.4 1.1 0.0 0.1 0.3 0.4 2.2 0.4 0.3 1.5 2.3 0.6 1.1 0.0 0.2 0.4 0.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.5 0.3 0.0 0.9 0.0 0.0 1.0 0.0 0.0 0.2 0.4 0.1 0.0 0.1 0.9 0.0 1.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.4 2.1 1.8 2.9 2.2 2.2 2.2 2.4 2.5 2.2 2.3 2.5 0.3 3.2 2.7 2.0 2.9 1.8 6.5 0.7 1.8 7.0 2.8 3.7 0.1 0.0 0.8 1.8 0.0 2.3 1.5 0.2 15.6 2.5 9.3 0.7 0.7 0.8 7.7 0.8 13.0 1.2 0.8 1.5 2.6 0.6 2.5 1.3 0.0 0.0 0.8 5.0 14.7 0.9 2.0 0.0 0.4 5.2 0.6 0.3 0.0 0.0 0.8 9.4 2.1 4.0 6.3 0.8 0.4 0.7 0.3 5.1 0.0 0.8 0.8 4.4 0.0 2.1 2.4 7.2 9.8 2.8 1.1 1.2 1.6 1.8 0.4 5.6 RBM44 FLJ40411 ENSG00000177483 "RNA binding motif protein 44" Q6ZP01 2 237798389-237842808 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 31 "testis: 15.7" "Group enriched" "Detected in many" 4 "Spermatocytes: 104.7;Spermatogonia: 59.8" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 13 "basophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA003298 Enhanced NA NA "Cluster 34: Basophils - Unknown function" "Cluster 36: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA003298: AB_2284846" "unprognostic (1.29e-1)" "unprognostic (2.66e-1)" "unprognostic (5.92e-2)" "unprognostic (1.56e-1)" "unprognostic (8.47e-3)" "unprognostic (3.15e-2)" "unprognostic (2.41e-1)" "unprognostic (2.60e-1)" "unprognostic (1.83e-2)" "unprognostic (8.12e-2)" "unprognostic (4.10e-2)" "unprognostic (4.57e-2)" "unprognostic (5.01e-5)" "unprognostic (1.90e-1)" "unprognostic (4.27e-2)" "unprognostic (6.85e-3)" "unprognostic (7.89e-3)" 0.3 0.0 0.0 0.1 0.0 0.5 0.3 0.0 0.1 0.3 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.2 0.2 0.0 0.3 0.1 15.7 0.0 0.0 0.1 0.3 0.1 0.2 0.2 0.0 0.0 0.0 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.3 0.3 0.0 0.1 0.0 0.2 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.6 0.1 0.0 0.2 0.0 0.0 0.2 0.4 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 1.1 1.6 0.4 0.8 0.7 0.3 0.6 0.0 0.8 0.3 0.7 1.5 1.5 1.8 0.0 0.1 2.2 0.0 0.0 0.1 16.8 2.0 0.5 2.4 0.0 0.0 2.4 0.2 0.3 1.0 0.0 4.6 0.0 0.3 0.0 0.2 0.3 0.0 3.3 0.0 0.0 0.8 2.3 16.1 2.8 1.5 1.8 1.9 1.4 0.0 1.0 3.0 0.4 0.6 0.0 1.5 1.0 2.0 0.1 0.1 1.8 0.0 6.6 2.6 0.7 104.7 59.8 0.2 0.6 0.0 0.8 0.7 0.0 1.6 RBMS1 "C2orf12, DKFZp564H0764, HCC-4, MSSP-1, MSSP-2, MSSP-3, SCR2, YC1" ENSG00000153250 "RNA binding motif single stranded interacting protein 1" P29558 2 160272151-160493807 "Predicted intracellular proteins" "DNA replication" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 398.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047943, HPA061791" Enhanced Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA047943: AB_2797235, HPA061791: AB_2684611" "unprognostic (2.81e-1)" "unprognostic (2.44e-2)" "unprognostic (3.78e-2)" "unprognostic (1.38e-3)" "unprognostic (2.50e-1)" "unprognostic (6.81e-3)" "prognostic unfavorable (4.45e-4)" "unprognostic (6.17e-2)" "unprognostic (4.85e-2)" "unprognostic (1.14e-1)" "unprognostic (7.16e-3)" "unprognostic (6.70e-2)" "prognostic unfavorable (1.33e-7)" "unprognostic (1.84e-3)" "unprognostic (1.50e-1)" "unprognostic (2.36e-1)" "unprognostic (2.32e-1)" 58.2 22.6 8.7 43.3 13.3 35.8 34.5 9.7 11.9 36.6 17.2 38.9 12.8 51.7 12.6 28.9 31.6 34.1 41.0 7.2 10.7 36.5 22.3 47.7 28.3 13.8 12.3 44.1 10.2 50.4 16.0 83.8 15.0 24.0 15.8 6.8 19.2 28.6 16.4 29.4 20.5 56.9 10.9 40.7 20.1 10.4 13.4 26.1 23.0 23.8 22.0 57.0 31.6 10.2 50.5 18.2 63.9 8.4 90.2 155.6 77.1 62.7 89.1 42.4 43.8 50.9 36.9 0.4 76.3 106.6 20.0 30.0 31.1 46.0 69.2 40.9 23.2 18.9 44.2 41.0 82.3 30.8 1.1 187.9 35.6 73.7 32.8 56.7 67.5 15.1 1.2 23.0 103.2 39.4 28.8 31.2 39.3 8.3 40.1 21.6 55.7 25.5 64.9 61.1 8.3 21.7 39.1 22.9 60.2 78.8 11.7 47.9 81.7 75.3 47.7 69.7 57.5 12.2 0.7 21.2 60.7 46.2 49.2 4.0 20.5 26.2 8.6 12.0 29.5 0.9 14.9 13.3 13.7 1.9 24.1 10.9 44.4 13.7 6.9 7.6 2.7 11.0 8.7 13.3 9.7 11.9 7.2 10.7 13.8 12.3 15.0 10.9 13.4 10.2 102.8 112.2 97.8 12.1 37.3 91.1 110.0 59.1 55.2 3.0 44.7 43.2 62.3 18.6 48.1 69.9 0.0 99.1 83.9 0.4 25.4 24.5 59.2 39.8 141.4 126.0 0.0 38.3 132.7 47.3 112.6 161.8 36.7 42.0 20.3 40.8 162.8 29.1 126.3 1.7 136.1 0.5 22.4 123.4 80.2 15.5 88.9 103.8 55.2 153.6 81.2 20.8 93.7 116.1 19.7 96.4 1.3 98.9 23.3 107.0 0.3 36.4 54.1 1.4 78.9 113.6 185.9 6.7 14.5 47.3 82.5 398.3 113.0 53.4 0.5 175.5 RBMS2 SCR3 ENSG00000076067 "RNA binding motif single stranded interacting protein 2" Q15434 12 56521820-56596193 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 74.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 78.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039225, HPA058784" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA039225: AB_10963056, HPA058784: AB_2683819" "unprognostic (1.35e-1)" "unprognostic (5.31e-2)" "unprognostic (2.61e-1)" "unprognostic (5.29e-2)" "unprognostic (9.09e-2)" "unprognostic (3.19e-3)" "unprognostic (4.78e-2)" "unprognostic (1.89e-2)" "unprognostic (7.01e-2)" "unprognostic (2.80e-1)" "unprognostic (2.86e-2)" "unprognostic (2.15e-1)" "prognostic favorable (3.22e-4)" "unprognostic (2.67e-2)" "unprognostic (4.73e-2)" "unprognostic (4.06e-3)" "unprognostic (2.63e-2)" 19.4 7.1 12.5 5.7 11.5 3.6 17.4 9.3 13.1 14.7 15.1 12.9 4.7 13.7 9.3 8.2 13.7 9.5 15.6 9.2 10.0 14.7 3.4 37.3 3.2 14.5 11.7 12.6 7.0 8.6 6.1 23.5 13.4 11.2 8.8 6.0 10.1 8.7 8.4 8.3 9.0 12.1 9.8 10.5 8.5 4.3 15.2 3.5 18.3 10.8 3.9 10.3 13.9 11.7 28.8 24.3 10.5 14.9 23.7 22.7 9.3 34.8 37.0 26.9 23.9 18.7 50.2 0.2 42.1 36.6 11.1 20.4 7.8 57.8 30.1 8.3 6.7 3.7 19.0 4.8 15.4 3.8 6.5 20.9 13.9 28.1 33.5 31.4 51.1 6.1 1.8 6.5 47.0 3.7 4.1 4.9 6.2 0.0 7.5 2.4 11.5 0.3 34.1 6.4 0.8 6.9 39.6 14.9 5.1 22.2 16.0 6.3 78.2 16.7 35.8 9.5 8.4 6.1 2.5 1.7 6.1 0.9 23.6 0.6 4.7 1.6 0.8 1.3 0.9 0.3 0.3 1.2 2.7 0.5 0.9 0.6 1.6 1.0 0.3 0.6 0.5 0.8 12.5 11.5 9.3 13.1 9.2 10.0 14.5 11.7 13.4 9.8 15.2 11.7 74.4 41.7 20.5 34.6 1.5 3.7 9.7 6.8 11.4 4.2 11.4 9.4 7.9 12.8 14.2 12.9 10.4 19.8 7.0 19.7 1.9 23.6 12.6 16.4 16.9 47.9 5.4 3.2 7.2 16.9 38.5 16.9 6.1 21.8 8.2 10.4 52.1 1.0 10.5 8.4 10.0 5.9 4.1 22.7 5.5 24.2 17.4 11.2 0.0 53.4 6.2 5.4 4.1 30.7 9.6 37.8 11.5 24.8 0.8 13.4 1.6 13.4 6.8 1.7 26.3 11.2 15.5 0.9 1.8 5.4 2.0 23.7 2.5 8.7 7.0 17.3 RGPD8 "RanBP2alpha, RANBP2L1" ENSG00000169629 "RANBP2 like and GRIP domain containing 8" O14715 2 112368369-112434488 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 15.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Early spermatids: 24.3;Excitatory neurons: 9.8;Late spermatids: 10.1;Microglial cells: 9.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 16.2;hTEC/SVTERT24-B: 13.4" "HPA045704, HPA049497, HPA051675, HPA067564" Uncertain Uncertain "Nuclear membrane,Vesicles" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 36: HEL - Hemostasis" "Cluster 59: Non-specific - Transcription" "Nuclear membrane, Vesicles" "HPA045704: AB_2679427, HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (1.37e-1)" "unprognostic (2.33e-1)" "unprognostic (1.05e-1)" "unprognostic (1.55e-1)" "unprognostic (3.62e-1)" "unprognostic (7.61e-2)" "unprognostic (2.65e-1)" "unprognostic (7.15e-3)" "unprognostic (3.17e-3)" "unprognostic (3.02e-2)" "unprognostic (2.78e-1)" "unprognostic (2.57e-1)" "unprognostic (9.18e-3)" "unprognostic (1.39e-1)" "unprognostic (1.31e-1)" "unprognostic (1.70e-1)" "unprognostic (1.05e-2)" 4.3 1.8 2.7 2.8 3.6 10.6 4.5 8.6 7.6 2.8 4.5 2.1 1.6 3.1 5.4 1.4 2.2 2.9 1.8 3.7 3.5 2.4 5.1 3.3 2.4 2.2 2.4 3.2 3.0 2.2 2.6 3.3 1.9 2.6 2.3 7.9 2.5 2.9 1.7 3.8 2.1 2.6 1.1 3.0 1.7 15.6 2.6 3.2 2.4 2.2 3.0 2.6 1.6 5.5 6.1 2.6 4.3 2.6 1.6 3.6 0.1 2.4 1.9 2.3 1.5 5.3 0.4 0.0 1.7 4.0 2.0 2.9 12.3 1.7 2.4 8.7 4.0 16.2 4.5 4.1 2.2 0.1 0.2 0.6 2.2 13.4 3.4 5.7 1.9 2.8 8.4 0.4 3.6 2.5 8.7 2.1 3.0 0.9 3.7 0.0 0.5 0.1 1.3 2.5 2.7 0.5 8.1 0.1 1.7 3.0 1.2 6.8 8.9 1.3 1.8 6.9 4.4 0.0 0.0 0.0 0.5 2.9 0.3 1.3 0.4 0.4 1.0 0.3 1.4 0.5 0.7 0.9 0.4 0.6 1.0 0.6 0.3 0.5 0.8 0.7 0.4 0.3 2.7 3.6 8.6 7.6 3.7 3.5 2.2 2.4 1.9 1.1 2.6 5.5 1.0 9.6 3.6 1.6 2.8 0.4 0.4 0.2 5.2 0.8 0.3 0.3 8.0 1.5 1.9 0.0 2.1 0.2 0.7 0.1 0.0 0.5 24.3 0.6 0.5 1.5 0.0 2.5 9.8 1.1 0.1 2.2 2.6 0.6 5.1 0.6 0.7 0.2 0.4 0.0 7.0 0.4 0.0 0.6 0.8 10.1 0.3 2.0 0.0 9.4 2.3 0.4 0.0 7.5 5.2 0.9 0.0 0.0 2.4 0.0 0.0 0.1 6.7 0.7 0.0 0.9 0.9 6.8 2.7 2.7 0.0 0.4 3.1 0.0 0.0 0.3 RHOJ "ARHJ, FLJ14445, RASL7B, TCL" ENSG00000126785 "Ras homolog family member J" Q9H4E5 14 63204114-63293508 "Predicted intracellular proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 41.0;Astrocytes: 176.0;Endothelial cells: 72.5;Hepatic stellate cells: 41.4;Microglial cells: 35.6;Oligodendrocyte precursor cells: 43.2;Skeletal myocytes: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 63.8;HUVEC TERT2: 375.4;TIME: 100.9;WM-115: 106.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003050 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA003050: AB_1079812" "unprognostic (7.24e-2)" "unprognostic (1.72e-1)" "unprognostic (4.37e-2)" "unprognostic (2.42e-1)" "unprognostic (6.71e-2)" "unprognostic (1.77e-2)" "unprognostic (2.89e-1)" "unprognostic (2.33e-2)" "unprognostic (2.19e-1)" "unprognostic (3.04e-3)" "unprognostic (1.42e-2)" "unprognostic (7.07e-2)" "prognostic unfavorable (1.31e-4)" "unprognostic (3.50e-3)" "unprognostic (4.84e-2)" "unprognostic (1.86e-2)" "unprognostic (1.06e-3)" 19.6 3.3 12.5 8.5 14.6 0.1 17.4 10.8 16.9 12.9 8.5 14.2 7.5 27.9 17.3 15.5 18.5 25.3 17.9 14.0 11.1 11.7 4.2 21.5 9.6 10.9 11.0 14.2 4.4 3.5 6.4 9.3 11.0 11.8 10.7 5.5 8.4 13.8 7.9 7.6 9.8 31.4 8.3 12.6 9.3 2.8 14.5 3.1 13.8 13.4 4.9 19.7 9.4 13.0 0.0 0.0 63.8 0.0 0.0 0.0 0.0 10.6 42.6 3.6 6.2 0.0 0.0 0.0 5.9 0.8 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.1 0.3 0.0 0.1 8.0 35.8 375.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.4 0.0 5.1 0.0 0.4 0.0 0.1 0.1 0.0 0.0 14.6 1.1 0.1 0.0 100.9 0.1 1.1 0.8 6.1 0.0 0.0 0.0 0.0 0.0 106.5 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 12.5 14.6 10.8 16.9 14.0 11.1 10.9 11.0 11.0 8.3 14.5 13.0 41.0 0.0 1.3 176.0 0.3 5.9 0.3 0.1 0.0 0.3 1.2 5.2 3.8 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 1.4 0.5 0.3 6.7 72.5 0.0 0.0 11.1 0.9 0.0 31.0 0.0 0.3 0.0 0.5 41.4 0.5 0.1 0.0 2.2 0.0 0.0 1.9 7.7 1.6 11.8 1.0 3.6 35.6 0.0 11.1 0.0 43.2 0.4 0.1 0.0 16.1 2.5 0.6 0.0 0.0 0.0 0.4 6.6 34.6 17.0 0.1 0.4 0.9 4.8 0.1 0.6 6.9 0.0 1.4 RHOU "ARHU, CDC42L1, DJ646B12.2, fJ646B12.2, FLJ10616, hG28K, WRCH-1, WRCH1" ENSG00000116574 "Ras homolog family member U" Q7L0Q8 1 228735479-228746664 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 119.2;Endometrial stromal cells: 100.4;Extravillous trophoblasts: 91.5;Oligodendrocytes: 139.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 99.2;MOLT-4: 46.5;RT4: 43.3;THP-1: 29.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049592 Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" "HPA049592: AB_2680827" "unprognostic (7.90e-2)" "unprognostic (1.18e-2)" "unprognostic (1.76e-2)" "unprognostic (8.26e-3)" "unprognostic (3.26e-2)" "unprognostic (2.57e-1)" "unprognostic (3.06e-2)" "unprognostic (1.43e-1)" "unprognostic (3.47e-2)" "unprognostic (2.00e-1)" "unprognostic (1.53e-1)" "unprognostic (6.21e-2)" "prognostic favorable (3.56e-5)" "unprognostic (4.20e-1)" "unprognostic (1.69e-1)" "unprognostic (1.52e-1)" "unprognostic (1.87e-2)" 29.2 11.1 21.9 5.6 34.2 8.4 16.5 25.9 39.8 17.0 14.6 15.2 23.6 13.8 5.7 6.1 18.9 16.8 12.2 21.8 24.9 11.4 26.0 13.8 3.8 28.6 31.3 25.6 18.6 13.8 7.3 17.5 27.1 17.8 9.9 2.3 18.5 10.4 37.3 6.2 23.9 8.5 25.4 15.4 22.5 9.5 31.9 4.7 13.7 5.0 1.1 18.3 8.9 41.5 1.0 2.5 7.9 0.6 1.8 0.9 99.2 0.5 0.9 0.6 0.4 11.0 14.8 0.0 5.8 1.3 0.5 0.6 2.9 0.0 0.5 16.0 5.6 0.1 0.7 3.4 11.0 8.1 0.9 0.5 0.8 0.2 0.5 0.1 0.2 4.0 0.0 0.0 0.5 2.5 46.5 8.5 2.5 13.5 0.9 0.2 2.5 1.3 0.4 43.3 2.9 8.7 0.9 6.7 0.0 16.9 0.0 29.9 0.7 0.1 1.2 0.0 0.1 2.3 10.6 0.0 0.0 20.5 5.2 0.0 0.3 0.4 0.4 0.5 0.8 0.0 0.3 0.6 0.4 0.0 0.0 0.2 0.0 0.1 0.2 0.4 0.0 0.1 21.9 34.2 25.9 39.8 21.8 24.9 28.6 31.3 27.1 25.4 31.9 41.5 76.4 16.0 16.4 16.6 0.7 4.6 3.6 0.5 0.0 4.5 27.4 18.9 77.3 38.6 15.6 1.8 0.0 25.9 5.1 82.1 0.0 4.7 0.7 119.2 100.4 28.9 3.0 3.2 13.6 8.9 91.5 28.9 20.4 83.7 0.0 56.8 30.7 40.8 21.9 8.4 6.9 10.3 4.1 28.3 38.6 3.1 1.8 29.9 16.0 5.6 15.1 5.5 1.0 24.6 139.5 5.1 35.7 1.2 1.9 23.0 64.3 1.2 21.0 0.9 0.0 21.5 10.2 1.5 2.8 0.3 3.3 33.9 5.9 1.2 9.6 18.6 RIN1 ENSG00000174791 "Ras and Rab interactor 1" Q13671 11 66330241-66336840 "Predicted intracellular proteins, RAS pathway related proteins" Endocytosis "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 26.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 25.7;Basal squamous epithelial cells: 23.3;Squamous epithelial cells: 18.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 9.7" "Lineage enriched" "Detected in many" 6 "monocytes: 9.7" "Cell line enhanced" "Detected in many" "hTCEpi: 44.3;U-2197: 40.7" "Low region specificity" "Detected in many" HPA035491 Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear membrane" Nucleoplasm "HPA035491: AB_10601608" "unprognostic (1.25e-2)" "unprognostic (1.04e-1)" "unprognostic (4.69e-2)" "prognostic favorable (2.21e-4)" "unprognostic (1.11e-2)" "unprognostic (2.57e-1)" "unprognostic (6.82e-3)" "unprognostic (3.84e-2)" "unprognostic (1.11e-2)" "unprognostic (2.52e-3)" "unprognostic (8.32e-2)" "unprognostic (2.99e-1)" "prognostic unfavorable (9.34e-7)" "unprognostic (2.42e-2)" "unprognostic (1.14e-1)" "unprognostic (7.82e-3)" "unprognostic (2.46e-1)" 4.8 4.3 3.7 2.3 4.9 1.1 4.4 3.3 5.7 8.3 1.5 5.2 2.7 4.4 0.2 20.4 5.6 1.4 3.4 6.3 1.6 4.3 1.3 4.9 0.5 1.0 1.2 3.7 5.2 0.4 7.2 1.4 1.1 7.1 1.0 0.2 5.1 0.8 7.5 26.6 4.3 0.6 0.8 6.1 6.8 3.7 2.0 0.5 2.4 0.5 0.4 5.4 11.3 2.6 2.3 5.7 2.3 5.3 2.8 14.5 1.2 13.7 18.0 14.4 6.8 3.3 9.3 0.5 5.0 13.6 5.2 12.9 0.0 24.3 1.8 1.1 0.0 0.8 4.4 4.1 5.5 0.1 4.2 15.9 44.3 12.4 8.0 17.1 2.8 0.6 0.3 0.1 6.1 0.5 0.3 11.0 0.6 3.9 12.6 0.1 5.4 0.1 3.9 3.0 10.9 2.3 3.2 2.5 20.5 0.6 1.8 1.3 6.5 18.7 7.9 40.7 3.3 0.3 0.9 0.0 26.9 3.5 6.3 0.1 2.7 0.0 0.2 4.7 0.6 0.1 0.4 0.2 1.7 0.0 0.5 0.2 0.0 0.1 9.7 0.0 0.1 1.8 3.7 4.9 3.3 5.7 6.3 1.6 1.0 1.2 1.1 0.8 2.0 2.6 3.9 0.0 0.5 1.3 0.8 13.4 9.3 25.7 23.3 3.8 3.5 4.3 0.8 4.3 4.8 0.0 0.0 0.8 0.5 9.6 0.0 4.1 0.5 2.4 5.1 5.3 3.0 0.0 6.0 6.9 4.8 5.6 5.6 1.8 4.5 0.1 7.9 0.2 4.7 0.0 2.3 4.5 2.0 8.7 6.5 2.0 4.4 6.4 1.8 1.0 8.1 0.7 1.0 0.5 0.5 8.9 7.8 1.9 1.4 4.0 9.1 0.1 3.4 1.2 0.0 4.2 3.4 1.2 0.9 18.6 15.2 0.3 2.2 1.6 9.2 5.8 RIPPLY3 DSCR6 ENSG00000183145 "Ripply transcriptional repressor 3" P57055 21 37006150-37019662 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein, Repressor" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 3.0;Extravillous trophoblasts: 2.9;Hepatic stellate cells: 1.8;Squamous epithelial cells: 1.6;Urothelial cells: 1.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.1;PC-3: 1.0;RPTEC TERT1: 1.3;RT4: 1.2;SCLC-21H: 3.9;T-47d: 3.2" "Low region specificity" "Detected in many" HPA055541 Uncertain NA NA "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA055541: AB_2682840" "unprognostic (1.77e-1)" "unprognostic (2.40e-2)" "unprognostic (3.01e-1)" "unprognostic (1.64e-2)" "unprognostic (2.43e-1)" "unprognostic (2.38e-3)" "unprognostic (2.19e-2)" "unprognostic (3.08e-1)" "unprognostic (1.91e-2)" "unprognostic (2.11e-2)" "unprognostic (2.17e-1)" "unprognostic (2.42e-1)" "unprognostic (2.14e-2)" "unprognostic (3.58e-1)" "unprognostic (2.31e-1)" "unprognostic (1.57e-4)" "unprognostic (2.69e-1)" 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 3.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 1.3 1.2 3.9 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.9 0.0 1.2 0.0 0.4 1.0 0.8 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.5 0.8 0.2 3.0 0.0 0.2 0.0 2.9 0.4 0.0 0.6 0.0 0.2 1.8 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 1.1 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.4 0.4 1.6 0.4 0.0 0.0 0.2 0.1 1.4 RNF145 FLJ31951 ENSG00000145860 "Ring finger protein 145" Q96MT1 5 159157409-159210053 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "B-cells: 11.4;granulocytes: 16.0;T-cells: 6.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036562 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Plasma membrane, Cytosol" "HPA036562: AB_10696657" "unprognostic (1.57e-1)" "unprognostic (9.02e-3)" "unprognostic (4.11e-2)" "unprognostic (3.88e-2)" "unprognostic (3.24e-2)" "unprognostic (2.93e-2)" "prognostic unfavorable (1.64e-6)" "unprognostic (1.35e-1)" "unprognostic (1.02e-2)" "unprognostic (1.54e-1)" "unprognostic (3.53e-1)" "unprognostic (1.67e-1)" "unprognostic (8.92e-3)" "unprognostic (1.49e-1)" "unprognostic (1.00e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-1)" 27.4 39.3 13.7 39.4 15.9 20.4 28.2 16.2 16.1 24.7 18.6 26.4 12.2 21.0 30.9 53.1 16.9 48.3 18.8 15.6 19.8 19.5 15.3 73.6 38.7 11.1 13.1 29.0 12.3 47.7 19.4 52.4 11.6 25.9 29.3 33.8 25.6 32.7 9.0 22.3 16.6 27.4 14.3 29.2 26.7 12.1 20.3 26.5 33.8 13.7 48.4 68.1 24.4 14.7 65.5 63.5 95.2 115.1 98.5 43.6 18.6 51.3 88.9 46.3 74.6 22.2 52.9 22.4 89.7 45.3 87.9 83.1 75.9 67.3 80.9 92.7 27.2 47.2 68.5 18.4 42.1 31.4 43.2 27.0 118.8 43.2 63.0 64.7 46.2 53.6 47.7 83.6 44.1 1.9 36.1 9.8 41.3 20.5 32.0 47.3 41.6 44.8 61.4 22.3 34.5 63.9 51.8 54.7 86.5 64.7 38.5 28.4 49.7 51.6 47.0 41.9 92.1 18.4 27.6 20.6 60.3 38.4 113.1 3.5 2.5 16.0 3.0 2.6 3.5 11.4 4.4 3.6 1.9 5.1 5.8 4.0 9.5 2.3 2.3 2.7 6.3 1.3 13.7 15.9 16.2 16.1 15.6 19.8 11.1 13.1 11.6 14.3 20.3 14.7 34.1 112.2 244.1 25.1 62.9 122.7 102.0 90.0 73.4 106.7 97.2 77.3 12.7 65.8 114.0 36.8 58.4 2.8 55.1 98.4 19.6 75.0 28.9 27.5 37.1 75.7 54.1 67.5 89.2 114.4 24.3 45.7 52.0 36.7 69.1 30.2 127.8 19.5 45.5 114.4 74.2 41.8 32.6 115.0 240.8 39.5 46.3 69.4 65.8 52.5 153.9 56.1 47.4 40.2 38.9 108.6 53.7 51.9 38.1 123.8 16.9 10.6 65.6 53.4 46.0 25.4 46.5 19.2 34.8 81.9 99.4 10.9 69.3 19.0 72.0 163.1 S100A16 "DT1P1A7, MGC17528, S100F" ENSG00000188643 "S100 calcium binding protein A16" Q96FQ6 1 153606886-153613145 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 2477.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 995.4;Pancreatic endocrine cells: 1307.3;Prostatic glandular cells: 1141.1;Squamous epithelial cells: 1028.7;Suprabasal keratinocytes: 908.8;Theca cells: 1528.4;Urothelial cells: 1522.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 1369.9;SK-BR-3: 1618.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045841 Enhanced Approved "Plasma membrane,Cytosol" NA NA 190000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "Plasma membrane" "HPA045841: AB_10966282" "unprognostic (9.86e-3)" "unprognostic (1.69e-1)" "unprognostic (2.23e-2)" "unprognostic (3.06e-1)" "unprognostic (1.71e-1)" "unprognostic (7.03e-2)" "prognostic unfavorable (3.18e-4)" "prognostic unfavorable (3.14e-5)" "unprognostic (1.70e-1)" "unprognostic (4.59e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.60e-1)" "prognostic unfavorable (3.91e-5)" "unprognostic (1.01e-1)" "unprognostic (1.92e-1)" "unprognostic (3.45e-2)" "unprognostic (5.29e-3)" 166.8 79.1 81.3 61.9 79.8 0.8 159.7 78.6 98.0 333.0 70.8 139.7 121.5 78.4 19.8 2477.7 68.2 81.6 122.3 79.8 80.1 219.0 209.9 161.3 28.4 104.2 80.9 83.4 41.0 76.6 42.0 71.8 84.9 77.8 105.0 7.0 438.1 38.1 51.7 474.9 109.8 79.0 84.8 118.5 100.4 60.3 103.4 25.0 72.4 52.1 205.0 163.2 713.3 84.6 670.4 318.1 16.0 36.7 102.5 386.8 42.8 367.9 341.4 302.7 265.2 315.4 366.1 0.3 577.5 553.0 69.0 479.6 1.1 839.2 175.3 1.9 0.6 0.4 260.5 90.8 117.5 0.2 0.9 182.7 787.6 731.6 567.9 390.9 1369.9 0.0 8.5 0.8 677.3 918.7 0.9 1.4 69.0 1171.0 887.9 0.9 187.4 1.8 1150.3 236.1 0.8 1.9 267.6 1618.0 55.7 140.5 504.7 3.5 743.9 178.2 289.5 171.5 848.6 0.5 3.5 2.4 525.0 0.9 122.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 81.3 79.8 78.6 98.0 79.8 80.1 104.2 80.9 84.9 84.8 103.4 84.6 275.6 38.5 25.5 10.4 6.8 633.9 995.4 531.6 157.6 0.5 225.4 191.3 33.0 124.4 290.6 108.5 2.1 20.3 4.4 500.7 72.4 610.9 4.9 50.9 172.5 293.5 139.0 16.0 0.0 193.9 8.7 112.2 96.8 128.5 19.1 154.1 365.9 132.7 5.0 0.0 0.1 286.4 164.8 15.7 95.4 17.4 67.1 7.4 112.1 5.6 7.2 72.5 0.0 7.5 0.7 1307.3 610.0 61.3 5.6 1141.1 353.3 169.7 48.6 2.1 6.6 70.9 91.2 8.0 1.3 1028.7 908.8 8.2 12.9 1528.4 320.2 1522.5 S100A3 S100E ENSG00000188015 "S100 calcium binding protein A3" P33764 1 153547329-153549258 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 94.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 15.4;Ductal cells: 21.7;Endometrial stromal cells: 18.4;Exocrine glandular cells: 24.0;Pancreatic endocrine cells: 24.2;Skeletal myocytes: 24.7" "Cancer enhanced" "Detected in all" "urothelial cancer: 26.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 9 "intermediate monocyte: 3.1;non-classical monocyte: 6.2;plasmacytoid DC: 7.4" "Group enriched" "Detected in many" 11 "dendritic cells: 7.4;monocytes: 6.2" "Cell line enhanced" "Detected in many" "A549: 87.0;HBEC3-KT: 45.7;HeLa: 51.4;U-2197: 47.4" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 15.8" "HPA042674, HPA056140" Enhanced Enhanced "Golgi apparatus,Plasma membrane,Cytosol" NA NA 240000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "Golgi apparatus, Plasma membrane" "HPA042674: AB_10796581, HPA056140: AB_2683050" "unprognostic (3.90e-2)" "unprognostic (1.60e-1)" "unprognostic (3.59e-2)" "unprognostic (1.21e-2)" "unprognostic (4.53e-2)" "unprognostic (5.37e-3)" "unprognostic (1.48e-1)" "unprognostic (2.36e-1)" "unprognostic (2.46e-1)" "unprognostic (2.08e-1)" "unprognostic (5.34e-3)" "unprognostic (3.97e-3)" "prognostic unfavorable (1.61e-6)" "unprognostic (8.13e-2)" "unprognostic (3.46e-1)" "unprognostic (6.21e-2)" "unprognostic (8.10e-2)" 7.6 1.1 0.9 3.6 1.1 1.8 4.2 0.8 1.3 6.9 0.6 2.8 0.5 3.9 0.2 17.2 3.3 1.7 2.6 0.8 1.4 13.8 0.2 16.6 1.8 1.4 1.6 1.1 0.8 0.1 0.7 2.2 1.2 3.0 1.1 0.0 4.2 1.7 1.0 94.6 1.9 2.1 1.1 0.8 1.4 0.5 2.8 0.4 1.5 1.9 5.1 6.9 9.6 1.4 7.3 87.0 0.1 0.1 8.1 5.2 0.0 6.1 31.4 7.9 12.8 2.6 2.8 0.1 19.0 16.1 10.7 22.2 0.1 45.7 3.7 0.3 0.0 0.3 51.4 15.3 2.2 0.0 0.3 4.1 24.9 17.9 19.9 4.5 1.7 0.0 0.0 0.0 39.8 0.5 0.0 0.0 0.6 0.2 11.5 0.0 5.9 4.7 26.0 18.3 1.2 0.0 5.4 6.1 2.0 24.7 0.2 0.6 8.6 2.9 4.8 47.4 6.3 1.4 1.6 0.2 38.2 0.7 19.1 0.0 0.1 0.0 0.0 3.1 0.2 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 6.2 7.4 0.1 0.4 0.9 1.1 0.8 1.3 0.8 1.4 1.4 1.6 1.2 1.1 2.8 1.4 2.0 3.2 0.5 0.7 0.0 10.3 2.3 15.4 4.0 0.0 0.3 0.4 0.3 1.5 5.9 0.0 0.0 0.3 0.0 0.0 1.9 21.7 0.0 2.3 18.4 7.4 0.0 1.3 0.0 24.0 4.4 8.4 0.0 1.3 0.0 0.0 2.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 11.1 0.1 4.1 0.4 1.8 0.0 3.6 0.0 0.0 0.0 0.0 24.2 0.0 0.4 0.0 1.5 0.0 0.3 1.1 0.0 0.0 24.7 9.6 0.1 0.0 5.6 6.5 1.5 0.5 1.1 0.0 2.0 SCARF1 "KIAA0149, SREC, SREC1" ENSG00000074660 "Scavenger receptor class F member 1" Q14162 17 1633858-1645744 "Predicted intracellular proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.6" "Cell type enhanced" "Detected in many" "Adipocytes: 65.9;Endothelial cells: 51.3;Hepatic stellate cells: 62.4;Langerhans cells: 37.7;Microglial cells: 26.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.2" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 12.1;REH: 11.5;TIME: 37.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035108, HPA072936" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" NA NA 2000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "HPA035108: AB_10670289, HPA072936: AB_2686559" "unprognostic (1.94e-1)" "unprognostic (2.84e-1)" "unprognostic (2.53e-3)" "unprognostic (2.88e-1)" "unprognostic (3.28e-1)" "unprognostic (2.15e-2)" "unprognostic (2.04e-1)" "unprognostic (2.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.91e-1)" "unprognostic (1.62e-2)" "unprognostic (3.76e-1)" "unprognostic (1.32e-1)" "unprognostic (2.13e-2)" "unprognostic (3.22e-2)" "unprognostic (1.38e-1)" "unprognostic (6.39e-2)" 15.2 5.0 1.5 3.1 1.8 0.4 12.7 1.4 3.4 5.6 1.4 5.2 0.0 6.0 0.9 2.7 6.5 2.2 11.8 1.6 1.8 7.5 7.5 16.3 2.1 2.7 1.7 2.6 3.1 0.1 3.8 4.3 2.2 4.6 1.2 0.2 4.2 0.0 5.3 3.1 5.4 1.2 1.7 25.6 4.2 1.6 1.7 0.5 18.8 1.9 1.0 5.6 4.6 2.8 0.0 0.1 0.3 0.3 0.0 0.1 0.4 0.1 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.1 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.3 12.1 0.3 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 11.5 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.3 37.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.2 1.5 1.8 1.4 3.4 1.6 1.8 2.7 1.7 2.2 1.7 1.7 2.8 65.9 22.4 17.6 6.5 0.6 3.4 0.4 0.7 1.2 1.2 0.8 0.9 3.5 0.0 2.9 3.7 4.2 0.4 2.0 4.9 1.9 0.4 0.3 0.5 0.9 51.3 0.0 3.4 5.4 0.2 0.2 2.5 4.1 1.1 3.8 0.3 62.4 2.3 9.0 0.0 3.5 4.4 0.0 15.7 37.7 0.4 1.2 10.1 3.6 26.2 4.8 0.7 0.0 0.5 1.1 0.3 1.2 1.2 0.0 0.7 3.0 0.2 3.0 2.0 0.0 2.1 3.0 0.5 0.6 0.3 2.7 1.2 1.0 1.3 2.2 0.8 SELENOK SELK ENSG00000113811 "Selenoprotein K" Q9Y6D0 3 53884417-53891962 "Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 373.5;Proximal tubular cells: 415.0;Syncytiotrophoblasts: 350.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "basophil: 471.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 471.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA008196 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" "HPA008196: AB_1856665" "unprognostic (1.29e-2)" "unprognostic (1.18e-2)" "unprognostic (3.85e-1)" "prognostic favorable (7.18e-4)" "unprognostic (9.92e-2)" "unprognostic (1.53e-1)" "unprognostic (3.02e-2)" "prognostic favorable (3.76e-4)" "unprognostic (2.75e-1)" "unprognostic (5.21e-2)" "unprognostic (8.34e-2)" "unprognostic (1.14e-1)" "unprognostic (3.40e-2)" "unprognostic (8.43e-2)" "unprognostic (8.12e-2)" "unprognostic (9.35e-2)" "unprognostic (2.56e-3)" 39.6 51.9 52.3 27.0 53.0 70.1 35.8 55.2 67.9 29.8 52.3 35.9 23.3 29.1 64.4 27.8 33.9 23.4 90.1 52.0 55.8 42.1 74.2 38.3 23.7 55.0 53.7 48.6 51.7 55.7 62.8 26.5 55.5 34.6 29.3 86.5 29.7 28.5 86.7 24.1 30.4 18.7 55.7 32.3 39.6 32.0 53.3 26.7 43.0 61.2 29.4 35.5 26.1 58.4 22.4 14.9 34.3 23.3 52.1 32.8 36.8 32.0 40.5 43.4 48.9 33.4 33.1 33.8 13.8 23.4 48.7 13.8 40.7 24.5 37.8 59.6 50.3 21.1 61.4 77.6 49.1 28.3 48.6 19.8 40.3 30.1 39.4 25.2 35.3 25.1 20.1 86.3 38.5 24.7 18.5 33.5 33.4 27.5 55.1 11.5 20.9 61.9 51.3 37.1 17.5 49.5 21.9 29.4 32.7 37.5 19.6 44.0 20.6 24.4 28.7 62.2 45.7 62.8 76.3 31.4 36.8 37.3 38.2 471.4 41.7 110.7 69.5 47.2 67.5 60.3 63.0 70.0 36.6 49.0 55.0 63.0 94.1 52.2 56.6 66.3 72.1 82.6 52.3 53.0 55.2 67.9 52.0 55.8 55.0 53.7 55.5 55.7 53.3 58.4 223.1 134.6 103.9 0.0 173.5 0.0 0.0 0.0 0.0 0.0 233.7 237.5 0.0 0.0 53.9 149.0 0.0 162.3 373.5 0.0 189.8 258.5 0.0 150.1 113.5 62.7 0.0 0.0 0.0 199.6 239.6 86.9 0.0 237.9 237.1 59.1 0.0 0.0 162.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 161.6 0.0 0.0 74.9 0.0 0.0 0.0 0.0 282.5 0.0 0.0 110.6 0.0 0.0 415.0 53.9 0.0 0.0 0.0 86.0 0.0 0.0 0.0 0.0 350.1 155.9 94.7 0.0 0.0 SEMA4C "Semacl1, Semaf, SEMAI" ENSG00000168758 "Semaphorin 4C" Q9C0C4 2 96859718-96870757 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 137.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 5 "BEWO: 298.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011090 Approved NA NA 700000 "Cluster 27: Non-specific - Gene expression" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA011090: AB_2185705" "unprognostic (1.25e-1)" "unprognostic (4.95e-2)" "prognostic unfavorable (3.53e-5)" "unprognostic (7.10e-2)" "unprognostic (4.46e-2)" "unprognostic (1.57e-2)" "unprognostic (4.20e-3)" "unprognostic (3.08e-1)" "unprognostic (2.16e-1)" "unprognostic (3.56e-2)" "unprognostic (1.82e-1)" "unprognostic (3.57e-1)" "prognostic unfavorable (9.50e-7)" "unprognostic (4.78e-3)" "unprognostic (3.09e-1)" "unprognostic (7.31e-2)" "unprognostic (4.08e-1)" 21.3 8.9 11.5 11.3 24.2 3.0 17.7 16.8 19.9 29.0 0.5 42.1 7.4 37.2 6.0 14.0 33.3 15.3 20.2 11.8 15.6 14.9 13.3 14.4 9.8 24.9 21.1 23.1 9.4 7.1 10.2 41.8 21.0 20.8 5.7 7.0 16.5 20.6 7.5 15.9 14.6 19.3 18.7 28.5 15.1 2.7 19.0 6.5 12.3 13.4 5.3 32.3 22.3 39.1 8.0 11.7 35.6 39.7 8.4 10.5 298.5 13.9 17.4 13.4 13.5 11.8 13.3 0.0 22.3 8.5 13.3 8.1 10.2 6.9 6.5 15.2 11.8 5.4 10.5 22.2 19.2 2.2 13.7 16.1 5.4 12.3 10.4 14.9 9.9 2.6 36.5 11.6 12.7 41.0 0.1 17.4 49.1 0.4 10.6 12.5 20.0 13.8 4.8 17.1 22.4 32.4 11.2 24.6 60.8 27.6 8.7 21.4 3.1 21.9 27.3 30.9 14.6 0.2 1.0 0.1 10.6 17.2 37.1 0.5 0.0 0.0 0.6 0.2 0.8 0.0 0.2 0.4 0.0 0.0 0.4 0.1 0.0 1.4 1.5 0.8 0.3 0.4 11.5 24.2 16.8 19.9 11.8 15.6 24.9 21.1 21.0 18.7 19.0 39.1 28.1 0.0 10.3 15.3 1.1 11.5 7.9 7.6 18.2 32.2 9.9 8.3 6.9 12.8 8.6 5.5 10.4 46.8 9.7 1.8 1.9 9.7 0.5 7.4 15.8 26.6 5.4 2.1 7.2 5.0 137.3 17.3 3.1 11.6 1.3 10.2 23.9 9.8 7.9 15.2 4.1 5.7 6.1 4.4 6.1 1.5 13.4 9.2 21.4 18.7 3.2 23.6 12.3 4.5 35.5 10.5 1.2 9.1 3.6 9.4 0.1 0.8 7.4 38.8 19.7 11.4 24.1 0.6 4.2 13.0 10.2 45.0 9.5 4.9 3.9 4.8 SEMA6B "SEM-SEMA-Y, SEMA-VIB, SEMAN, semaZ" ENSG00000167680 "Semaphorin 6B" Q9H3T3 19 4542593-4581776 "Disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.3" "Cell type enhanced" "Detected in many" "Adipocytes: 43.6;Alveolar cells type 1: 28.9;Alveolar cells type 2: 44.6;Endothelial cells: 40.1;Excitatory neurons: 30.6;granulocytes: 29.7;Hepatic stellate cells: 37.5;Inhibitory neurons: 30.3;Macrophages: 35.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 124.5;HMC-1: 198.1;HUVEC TERT2: 83.8;TIME: 107.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025157, HPA055778, HPA058523" Enhanced NA NA 1100000 "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "CAB025157: , HPA055778: AB_2682916, HPA058523: AB_2683741" "unprognostic (4.03e-1)" "unprognostic (9.69e-3)" "unprognostic (6.38e-3)" "unprognostic (2.15e-1)" "unprognostic (1.15e-1)" "unprognostic (7.94e-2)" "unprognostic (2.10e-1)" "unprognostic (4.34e-3)" "unprognostic (6.61e-2)" "unprognostic (1.90e-1)" "unprognostic (4.21e-2)" "unprognostic (2.82e-1)" "prognostic unfavorable (3.29e-5)" "unprognostic (1.26e-1)" "unprognostic (1.81e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (9.55e-2)" 25.6 19.7 44.0 11.0 30.7 7.8 17.1 0.6 72.3 8.7 0.0 6.6 4.0 10.6 0.4 3.6 8.8 5.8 20.2 65.2 12.4 13.3 2.9 10.7 1.2 13.5 11.0 3.3 4.1 9.2 7.2 8.9 1.8 7.0 1.0 1.4 3.9 1.3 6.0 4.6 7.3 6.9 0.5 31.9 6.1 1.9 30.2 0.7 9.1 4.3 0.7 10.0 6.7 17.4 7.2 25.0 2.3 21.4 0.1 1.2 0.2 0.0 0.7 2.4 0.6 0.2 2.0 0.0 23.7 0.0 3.8 4.4 6.5 0.0 0.9 0.1 1.0 0.0 0.4 124.5 0.4 0.0 198.1 7.5 0.1 0.2 0.2 24.9 83.8 0.1 1.6 0.3 0.7 6.5 0.0 0.0 26.8 1.7 0.3 0.4 46.8 0.6 1.7 0.1 17.7 1.7 0.1 1.7 11.5 1.8 2.7 1.1 107.8 3.1 34.7 0.5 18.6 1.3 0.0 0.4 0.8 1.3 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.0 30.7 0.6 72.3 65.2 12.4 13.5 11.0 1.8 0.5 30.2 17.4 43.6 28.9 44.6 2.6 2.3 4.7 1.5 0.5 0.0 9.0 2.1 1.9 1.9 1.5 19.3 1.8 4.2 0.6 2.3 0.2 0.0 1.1 1.1 1.1 2.5 40.1 0.0 8.4 30.6 0.2 0.6 8.2 0.0 2.0 29.7 0.5 37.5 6.0 3.3 18.5 30.3 0.1 0.0 6.1 18.1 0.4 0.6 35.2 7.2 7.5 1.4 2.0 1.0 19.1 1.4 0.2 0.1 0.7 1.1 1.2 0.0 0.4 17.7 4.1 0.0 8.8 1.8 2.0 2.2 0.0 5.1 0.3 5.4 1.6 0.1 0.9 SERPINB1 "anti-elastase, EI, ELANH2, PI2" ENSG00000021355 "Serpin family B member 1" P30740 6 2832332-2841959 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 466.8;esophagus: 478.3" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 1424.3;Pancreatic endocrine cells: 1067.8;Urothelial cells: 984.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 125.3;OE19: 162.5;U-937: 144.9" "Low region specificity" "Detected in all" "HPA018871, HPA018882, HPA052642" Enhanced Supported "Cytoplasmic bodies" "Secreted to blood" NA NA 24000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Cytoplasmic bodies" "HPA018871: AB_1856724, HPA018882: , HPA052642: AB_2681896" "unprognostic (1.13e-2)" "unprognostic (1.93e-1)" "unprognostic (6.07e-2)" "unprognostic (1.75e-2)" "unprognostic (5.14e-3)" "unprognostic (9.67e-2)" "unprognostic (3.59e-3)" "unprognostic (1.13e-1)" "unprognostic (1.45e-1)" "unprognostic (1.88e-2)" "unprognostic (1.08e-3)" "unprognostic (9.07e-2)" "unprognostic (1.05e-1)" "unprognostic (2.16e-1)" "unprognostic (1.47e-1)" "unprognostic (1.67e-1)" "unprognostic (2.28e-1)" 36.6 54.4 10.7 69.7 14.4 466.8 25.0 11.1 14.0 55.6 17.3 77.7 140.4 15.6 22.2 478.3 35.8 57.4 26.8 10.7 12.7 33.2 32.1 81.7 51.3 15.1 13.0 18.1 232.1 29.8 32.9 27.0 14.6 15.9 87.5 13.4 99.6 16.9 54.2 15.8 107.3 24.9 13.6 67.4 97.9 7.1 13.7 31.9 30.7 22.9 122.8 88.6 112.4 14.8 42.9 49.7 2.7 0.3 10.6 21.8 41.2 11.8 36.1 14.5 26.1 47.1 125.3 0.3 86.6 26.6 15.6 26.8 4.8 11.4 11.1 59.4 7.5 76.6 16.0 37.0 37.2 13.5 46.2 26.8 18.4 7.3 3.3 7.2 48.7 0.0 27.1 9.9 13.4 19.9 1.7 35.4 4.5 162.5 22.1 3.9 0.5 44.4 51.0 9.3 8.8 4.8 28.8 11.2 64.2 5.9 5.6 43.2 29.1 4.6 10.4 10.2 3.6 0.1 2.2 0.5 17.4 144.9 2.4 118.0 207.1 109.4 53.3 103.7 45.8 43.5 48.1 48.4 150.4 32.3 47.4 50.6 182.3 85.1 82.8 48.6 58.5 175.8 10.7 14.4 11.1 14.0 10.7 12.7 15.1 13.0 14.6 13.6 13.7 14.8 79.9 240.4 269.9 0.7 90.7 35.1 165.1 699.1 38.1 4.2 55.0 51.2 17.6 72.9 420.9 46.0 2.1 124.5 120.8 264.1 56.7 490.3 1.7 210.6 28.7 118.9 96.3 176.3 0.9 1424.3 149.1 89.1 345.1 104.5 452.2 32.1 124.9 20.2 183.0 10.1 0.9 263.1 109.9 332.7 308.2 3.5 34.8 387.3 71.2 15.9 589.7 48.3 139.0 4.5 6.6 1067.8 308.4 27.8 65.2 147.5 333.7 81.3 343.8 17.2 13.1 109.7 67.2 2.0 11.2 461.5 38.1 99.7 112.9 59.2 242.6 984.3 SH2B3 "IDDM20, LNK" ENSG00000111252 "SH2B adaptor protein 3" Q9UQQ2 12 111405923-111451623 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 60.7" "Cell type enhanced" "Detected in many" "Kupffer cells: 113.6;Langerhans cells: 130.9;Macrophages: 84.1;monocytes: 67.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 122.2;hTEC/SVTERT24-B: 140.7;U-87 MG: 211.6;WM-115: 165.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005483 Approved Approved Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA005483: AB_1079260" "unprognostic (2.77e-1)" "unprognostic (1.74e-1)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (1.18e-1)" "unprognostic (9.09e-2)" "unprognostic (1.23e-1)" "unprognostic (2.42e-1)" "unprognostic (1.18e-1)" "unprognostic (4.65e-2)" "unprognostic (8.17e-3)" "unprognostic (9.08e-2)" "prognostic unfavorable (6.20e-4)" "unprognostic (2.86e-1)" "unprognostic (3.89e-3)" "unprognostic (1.11e-1)" "unprognostic (2.24e-2)" 22.2 10.9 10.2 21.9 6.8 60.7 13.3 3.5 9.3 8.6 8.5 11.4 8.1 8.5 3.3 7.7 8.1 18.6 23.4 5.8 6.5 14.3 17.4 20.5 21.0 12.0 7.3 5.5 10.2 5.8 8.0 24.4 10.0 7.3 13.5 3.7 5.3 5.9 9.6 4.1 12.5 13.6 10.1 37.1 7.1 9.5 12.1 10.5 11.1 9.5 15.8 15.7 6.0 14.7 9.2 5.5 7.0 7.3 23.9 35.5 4.8 29.2 79.5 21.9 23.3 8.4 5.2 15.6 20.3 44.6 73.6 1.7 5.5 16.9 35.2 13.3 2.7 53.2 2.6 6.2 23.3 23.5 122.2 21.2 3.8 140.7 12.7 48.4 119.1 12.8 38.9 6.1 80.2 3.2 9.7 46.7 11.0 2.4 21.0 9.5 15.9 10.2 10.5 3.7 4.6 4.9 5.4 0.6 42.2 6.2 3.5 33.4 93.0 20.0 11.3 17.4 48.1 13.9 15.8 17.6 211.6 16.6 165.3 0.9 3.5 1.2 1.2 8.4 1.0 1.5 1.1 1.3 4.8 0.5 0.7 1.0 3.0 1.8 6.6 4.9 0.4 1.8 10.2 6.8 3.5 9.3 5.8 6.5 12.0 7.3 10.0 10.1 12.1 14.7 26.8 3.2 22.0 2.6 26.2 6.8 1.5 4.2 1.2 4.6 4.3 3.8 17.5 4.3 4.3 1.8 2.1 0.4 40.6 15.0 1.9 3.6 13.1 1.0 2.2 39.2 3.5 11.2 11.0 9.0 1.4 8.1 0.5 1.2 38.6 0.8 46.1 11.1 40.4 3.3 7.3 3.0 6.1 113.6 130.9 5.3 2.8 84.1 16.0 38.4 67.1 1.1 18.6 11.1 9.0 7.2 5.9 4.1 4.9 3.0 0.8 1.5 3.5 3.4 0.0 4.0 12.7 12.5 4.5 0.7 4.1 1.0 12.1 4.4 3.2 1.2 SH2D3C NSP3 ENSG00000095370 "SH2 domain containing 3C" Q8N5H7 9 127738317-127778710 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 52.6;dendritic cells: 29.7;Endothelial cells: 52.2;Hepatic stellate cells: 41.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 53.3;HUVEC TERT2: 60.0;REH: 60.7;RPMI-8226: 46.1;TIME: 50.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047586 Enhanced Supported Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA047586: AB_2680093" "unprognostic (8.33e-2)" "unprognostic (4.77e-3)" "unprognostic (3.28e-2)" "prognostic favorable (9.47e-4)" "unprognostic (5.23e-2)" "prognostic favorable (1.98e-4)" "unprognostic (3.75e-2)" "unprognostic (2.22e-1)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (2.58e-3)" "unprognostic (1.61e-1)" "unprognostic (1.88e-3)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (1.18e-1)" "unprognostic (5.28e-2)" 27.3 7.6 11.2 15.9 10.5 11.2 24.9 11.7 13.2 12.2 2.8 7.6 4.5 15.8 1.2 5.8 12.6 9.2 44.7 10.7 9.6 19.9 4.7 52.2 25.8 8.6 7.5 5.0 4.8 3.9 7.1 15.8 8.4 8.5 1.8 0.8 6.8 3.5 14.6 7.4 15.1 7.3 8.1 47.2 7.3 5.1 8.9 27.8 22.9 11.4 10.5 10.9 9.4 8.0 0.1 0.2 0.9 0.2 0.8 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 19.5 1.1 0.0 1.1 0.7 0.0 0.0 0.0 15.6 0.3 7.3 0.1 0.0 0.3 5.6 53.3 0.3 0.2 0.3 0.1 0.0 60.0 11.6 0.2 20.6 0.0 0.1 5.1 16.8 0.8 0.0 0.0 60.7 0.9 46.1 0.0 0.0 14.5 4.4 0.3 0.1 0.0 1.4 0.1 9.6 50.1 0.0 1.2 0.1 0.1 20.3 22.2 20.3 0.4 4.8 0.0 34.0 29.9 37.8 32.3 94.7 26.4 26.2 18.8 30.4 32.8 29.5 16.6 17.5 82.2 34.6 124.8 59.8 21.6 34.2 11.2 10.5 11.7 13.2 10.7 9.6 8.6 7.5 8.4 8.1 8.9 8.0 52.6 3.2 5.8 0.7 15.9 1.3 0.3 1.9 0.6 3.2 1.1 1.7 10.5 2.8 0.9 0.0 0.0 0.3 29.7 0.0 0.0 0.5 13.8 2.2 2.8 52.2 4.2 3.6 10.8 0.0 0.2 3.1 2.0 0.8 11.4 0.0 41.7 0.7 6.0 3.3 10.7 0.3 0.0 6.0 3.7 16.3 1.2 10.7 1.8 23.4 13.4 3.6 21.6 3.0 0.7 0.1 0.0 0.7 7.6 0.1 0.0 0.1 0.8 2.4 6.6 1.2 12.5 1.8 1.5 0.9 0.4 0.7 15.5 2.0 0.1 0.2 SHROOM4 KIAA1202 ENSG00000158352 "Shroom family member 4" Q9ULL8 X 50591642-50814302 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.7" "Group enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 126.7;Oligodendrocytes: 463.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.7;HUVEC TERT2: 26.7;RH-30: 5.0;RPTEC TERT1: 5.5;TIME: 10.0;WM-115: 5.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA010089, HPA010565" Uncertain Approved "Nucleoplasm,Vesicles,Focal adhesion sites" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Focal adhesion sites" "Nucleoplasm, Vesicles" "HPA010089: , HPA010565: AB_1079961" "unprognostic (2.55e-2)" "unprognostic (1.43e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.34e-1)" "unprognostic (1.60e-2)" "unprognostic (4.30e-3)" "unprognostic (4.55e-2)" "unprognostic (2.13e-1)" "unprognostic (2.93e-1)" "unprognostic (1.52e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (4.66e-4)" "unprognostic (7.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.74e-2)" "unprognostic (2.75e-1)" 8.1 1.8 9.8 1.9 20.0 1.2 5.4 17.1 12.4 3.3 0.9 1.8 1.1 3.6 1.6 2.7 2.2 3.0 7.8 8.9 12.6 5.3 0.9 13.3 0.9 23.8 17.6 1.3 0.9 1.9 2.0 9.0 21.8 2.2 1.4 1.3 2.0 1.8 3.6 1.7 1.5 4.1 13.8 1.0 1.3 0.6 17.3 0.6 3.3 5.0 1.0 3.5 2.3 30.7 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.1 0.2 0.0 6.7 0.9 0.0 0.6 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.0 0.0 0.5 0.0 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 5.0 0.0 5.5 2.5 0.1 0.0 0.0 0.8 1.5 3.6 0.1 0.1 10.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 1.3 0.2 5.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 20.0 17.1 12.4 8.9 12.6 23.8 17.6 21.8 13.8 17.3 30.7 45.0 25.6 18.6 3.3 0.0 3.6 2.0 1.9 2.2 0.3 1.0 1.5 4.2 0.0 2.0 5.5 0.0 0.6 0.2 1.1 3.9 0.7 0.1 2.8 5.4 46.5 3.0 0.0 1.1 0.2 3.0 3.0 0.0 2.9 3.8 2.3 30.7 0.9 0.5 0.0 1.1 2.8 0.0 2.4 2.7 0.6 1.2 0.6 0.0 51.5 0.0 3.6 0.0 126.7 463.4 2.3 1.0 1.2 0.0 1.2 0.3 3.5 2.5 0.6 0.0 2.5 2.6 0.0 1.0 2.0 3.1 0.3 0.6 3.0 3.2 1.6 SIPA1L2 "KIAA1389, SPAR2" ENSG00000116991 "Signal induced proliferation associated 1 like 2" Q9P2F8 1 232397965-232630571 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 80.2;Inhibitory neurons: 95.9;Microglial cells: 183.6;Oligodendrocyte precursor cells: 104.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 69.7;NTERA-2: 53.9;WM-115: 46.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024181, HPA027224" Approved Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies,Golgi apparatus" No NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nuclear membrane, Nuclear bodies" "Golgi apparatus" "HPA024181: AB_1856886, HPA027224: AB_2672165" "unprognostic (2.34e-2)" "unprognostic (9.67e-2)" "unprognostic (8.02e-2)" "unprognostic (1.71e-3)" "unprognostic (2.98e-1)" "unprognostic (5.68e-2)" "unprognostic (5.57e-3)" "unprognostic (7.79e-2)" "unprognostic (1.60e-1)" "unprognostic (1.80e-2)" "unprognostic (3.77e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (8.15e-4)" "unprognostic (3.36e-2)" "unprognostic (2.75e-1)" "unprognostic (5.84e-3)" "unprognostic (3.45e-3)" 12.1 3.3 8.5 6.4 7.2 5.4 9.2 9.6 11.7 10.0 0.5 19.4 3.9 4.4 2.8 20.3 4.5 8.5 31.3 9.6 16.0 7.7 6.4 16.2 3.0 44.0 21.7 11.9 3.6 4.4 8.1 18.3 44.6 8.1 18.9 14.7 8.7 4.7 7.1 9.0 9.2 7.4 14.4 9.6 5.7 7.2 18.7 2.4 8.0 9.5 3.3 12.5 14.9 9.0 0.0 7.5 69.7 0.2 0.6 0.0 29.3 1.2 2.5 3.1 2.2 2.9 0.1 5.9 13.3 26.4 2.9 1.7 13.8 2.3 2.9 0.0 12.8 0.0 7.0 0.0 5.9 1.0 7.2 3.8 9.1 0.6 6.2 0.0 15.7 25.4 0.0 0.1 1.6 3.5 7.4 0.7 53.9 0.2 10.2 0.0 0.0 3.4 8.1 11.5 3.5 11.9 23.8 0.8 9.5 15.8 1.4 0.6 5.6 8.1 0.0 17.8 2.9 6.5 0.0 0.0 10.0 6.2 46.1 0.0 0.2 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.4 0.6 0.3 0.3 0.0 0.1 8.5 7.2 9.6 11.7 9.6 16.0 44.0 21.7 44.6 14.4 18.7 9.0 53.7 6.4 1.8 22.9 0.8 8.8 9.8 8.7 15.4 23.5 10.7 8.6 62.6 12.8 10.4 3.7 52.1 4.9 4.4 29.9 0.0 7.1 11.7 19.0 21.4 22.7 7.2 0.4 80.2 0.5 7.1 15.2 5.1 47.5 1.3 16.0 1.8 3.8 10.0 5.0 95.9 29.5 14.2 16.6 7.2 9.8 0.9 19.5 14.2 183.6 6.3 12.7 1.0 104.0 21.0 1.4 39.9 1.9 0.5 13.2 9.1 0.4 7.7 35.7 0.0 21.8 23.9 6.9 24.0 45.8 7.4 14.8 2.0 11.9 23.4 23.0 SLC16A14 "FLJ30794, MCT14" ENSG00000163053 "Solute carrier family 16 member 14" Q7RTX9 2 230034982-230068993 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 18.6" "Cell type enhanced" "Detected in many" "Adipocytes: 17.0;Excitatory neurons: 18.5;Inhibitory neurons: 21.1;Microglial cells: 45.0;Oligodendrocyte precursor cells: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "eosinophil: 11.3" "Lineage enriched" "Detected in single" 24 "granulocytes: 11.3" "Cell line enhanced" "Detected in many" "HL-60: 24.2;Karpas-707: 15.2;REH: 19.5;RPMI-8226: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040518 Uncertain Approved "Endoplasmic reticulum" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA040518: AB_10794877" "unprognostic (2.99e-1)" "unprognostic (1.74e-1)" "unprognostic (2.63e-1)" "unprognostic (1.74e-3)" "unprognostic (2.20e-3)" "unprognostic (2.01e-1)" "unprognostic (4.96e-2)" "unprognostic (1.95e-1)" "unprognostic (3.15e-1)" "unprognostic (5.70e-3)" "unprognostic (1.22e-2)" "unprognostic (2.23e-1)" "unprognostic (1.03e-3)" "unprognostic (3.51e-1)" "unprognostic (2.39e-1)" "unprognostic (6.06e-2)" "unprognostic (2.10e-1)" 4.6 3.9 7.9 1.7 7.2 5.6 3.2 8.9 7.7 5.0 2.4 3.7 1.0 3.9 2.3 4.0 3.1 2.8 2.4 7.1 7.2 2.3 2.0 1.9 1.3 5.2 6.1 7.3 0.8 7.0 1.4 1.2 4.7 4.5 4.0 2.5 18.6 3.6 1.0 11.0 1.3 3.8 3.8 5.9 1.4 1.2 9.4 2.2 1.5 2.0 1.5 2.0 2.7 4.7 2.9 1.6 1.3 0.0 0.0 0.3 0.0 0.3 0.0 0.6 0.4 0.0 0.5 0.0 0.3 0.1 0.0 0.5 5.1 1.4 0.1 0.0 9.7 0.2 3.1 0.0 0.3 24.2 0.0 0.5 3.6 0.0 0.0 3.9 0.2 4.7 0.0 15.2 0.3 0.0 2.4 2.7 1.0 0.3 2.7 19.5 0.0 17.3 5.6 2.6 6.3 2.3 4.9 0.0 0.1 0.1 7.7 1.9 0.0 0.0 1.3 3.3 2.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 11.3 0.4 0.0 0.3 0.3 0.1 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.9 7.2 8.9 7.7 7.1 7.2 5.2 6.1 4.7 3.8 9.4 4.7 17.0 0.0 0.0 2.3 1.5 2.5 0.5 1.9 3.4 3.3 1.2 0.8 3.9 0.0 3.5 0.0 2.1 0.0 0.1 1.8 0.0 0.8 0.0 0.5 2.6 10.8 3.6 0.0 18.5 0.6 0.0 2.3 0.0 0.3 0.0 0.2 4.2 2.1 0.1 3.3 21.1 0.3 4.1 0.3 0.6 0.0 1.2 0.1 1.8 45.0 0.0 1.9 0.0 13.6 1.8 0.8 1.0 3.0 8.4 0.9 0.0 0.3 1.6 1.6 0.0 0.5 1.4 0.2 0.2 6.8 4.7 0.3 1.4 8.4 1.3 0.3 SLC25A2 ORNT2 ENSG00000120329 "Solute carrier family 25 member 2" Q9BXI2 5 141302635-141304049 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 24 "testis: 6.6" "Group enriched" "Detected in some" 21 "Early spermatids: 18.2;Late spermatids: 12.0;Spermatocytes: 27.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042146 Uncertain NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA042146: AB_2677874" "unprognostic (1.55e-1)" "unprognostic (3.53e-1)" "unprognostic (4.63e-2)" "unprognostic (4.30e-1)" "unprognostic (1.71e-1)" "unprognostic (1.30e-1)" "unprognostic (4.72e-3)" "unprognostic (2.81e-1)" "unprognostic (2.62e-2)" "unprognostic (6.69e-2)" "unprognostic (1.17e-1)" "unprognostic (8.82e-10)" "unprognostic (2.56e-1)" "unprognostic (1.87e-1)" "unprognostic (1.26e-2)" "unprognostic (1.14e-1)" 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 6.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 27.6 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 SLC26A5 "DFNB61, PRES" ENSG00000170615 "Solute carrier family 26 member 5" P58743 7 103352730-103446207 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell shape, Hearing" "Motor protein" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Astrocytes: 5.5;Excitatory neurons: 4.1;Gastric mucus-secreting cells: 7.1;Hepatic stellate cells: 5.3;Inhibitory neurons: 3.5;Microglial cells: 6.5;Oligodendrocytes: 4.2" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in single" "cerebellum: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 4 "basal ganglia: 10.4" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (3.86e-2)" "unprognostic (5.13e-2)" "unprognostic (6.38e-3)" "unprognostic (2.76e-2)" "unprognostic (1.02e-2)" "unprognostic (5.09e-2)" "unprognostic (2.36e-1)" "unprognostic (3.56e-4)" "unprognostic (4.21e-3)" "unprognostic (8.92e-3)" "unprognostic (2.82e-1)" "unprognostic (2.97e-1)" "unprognostic (3.67e-5)" "unprognostic (3.05e-1)" "unprognostic (2.81e-1)" "unprognostic (2.94e-2)" "unprognostic (2.69e-3)" 0.1 0.1 0.3 0.0 0.3 0.0 0.7 2.2 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.4 0.1 0.4 0.5 0.0 0.2 0.3 0.0 0.0 0.3 0.4 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.4 0.1 0.6 0.2 0.3 0.0 0.2 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 2.2 0.2 0.1 0.4 0.4 0.5 0.3 0.4 0.3 0.5 0.3 6.4 2.6 5.5 0.2 0.3 0.0 0.0 0.0 0.2 0.3 0.1 0.7 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.4 0.2 0.5 0.0 0.0 4.1 0.0 0.0 2.2 7.1 0.2 0.0 0.0 5.3 0.0 0.0 0.0 3.5 0.0 0.0 0.3 0.3 0.0 0.3 0.0 0.0 6.5 0.0 0.3 0.0 2.0 4.2 0.3 0.0 0.0 0.0 0.8 0.0 0.0 2.2 1.2 0.0 0.2 0.1 0.3 0.5 0.0 0.3 0.0 0.6 0.0 0.0 0.6 SLC35G2 "DKFZp564K2464, MGC3295, TMEM22" ENSG00000168917 "Solute carrier family 35 member G2" Q8TBE7 3 136818647-136855888 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 54.2;Early spermatids: 65.4;Inhibitory neurons: 42.4;Spermatocytes: 35.5" "Cancer enhanced" "Detected in many" "glioma: 6.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD8 T-cell: 1.0" "Lineage enriched" "Detected in single" 10 "T-cells: 1.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 73.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052054, HPA064728" Approved Supported "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA052054: AB_2681709, HPA064728: AB_2685336" "unprognostic (1.04e-1)" "unprognostic (1.46e-2)" "unprognostic (6.91e-4)" "unprognostic (2.56e-4)" "unprognostic (5.34e-2)" "unprognostic (6.73e-2)" "unprognostic (1.16e-5)" "unprognostic (1.83e-3)" "unprognostic (1.12e-1)" "unprognostic (6.39e-2)" "unprognostic (1.49e-2)" "unprognostic (3.32e-1)" "prognostic unfavorable (1.16e-7)" "unprognostic (1.00e-2)" "unprognostic (1.69e-1)" "unprognostic (1.07e-2)" "unprognostic (2.30e-2)" 14.9 15.4 20.9 2.1 21.2 0.5 11.1 23.1 26.4 5.1 16.5 3.8 1.0 4.3 4.6 2.6 5.7 5.3 8.1 20.0 24.4 3.9 4.4 7.0 1.9 21.4 25.0 5.5 7.6 6.7 19.3 7.4 26.9 4.1 2.0 5.3 3.1 2.6 2.4 3.7 2.9 5.1 22.1 3.2 2.9 14.4 22.6 2.8 8.5 5.4 1.2 6.5 5.0 21.0 3.9 10.7 10.6 4.8 20.8 17.1 0.0 16.9 73.1 24.7 37.0 10.1 5.7 0.0 12.7 17.5 39.3 1.3 12.7 0.7 22.8 0.1 3.5 3.2 12.0 6.3 26.6 0.1 0.0 24.2 1.8 21.5 5.9 18.0 18.8 6.8 1.8 0.1 32.1 0.0 4.7 3.3 2.3 0.0 7.9 4.2 7.1 0.2 21.1 0.9 17.5 11.7 13.7 0.0 24.0 3.6 0.0 1.8 13.1 18.4 4.7 8.2 18.6 0.0 0.0 0.0 25.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 20.9 21.2 23.1 26.4 20.0 24.4 21.4 25.0 26.9 22.1 22.6 21.0 22.4 12.8 7.0 54.2 2.5 3.3 4.9 12.0 7.4 4.7 0.7 0.8 2.5 1.5 7.1 1.8 12.5 1.3 2.7 0.8 1.9 3.3 65.4 1.0 1.6 30.6 4.2 4.4 34.0 10.7 1.3 12.4 0.5 1.3 2.5 3.6 27.8 2.3 0.7 6.7 42.4 1.0 0.0 2.2 7.3 30.3 9.9 2.1 3.6 17.8 3.7 7.8 15.5 15.6 6.1 10.0 0.1 3.0 3.7 4.7 0.6 0.7 1.4 4.6 6.6 4.7 4.8 35.5 16.1 1.2 3.0 2.2 3.8 3.1 0.6 2.0 SNRK "FLJ20224, HSNFRK, KIAA0096" ENSG00000163788 "SNF related kinase" Q9NRH2 3 43286512-43424764 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 124.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 126.0;TIME: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042163 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Vesicles, Plasma membrane, Cell Junctions" Nucleoplasm "HPA042163: AB_10794645" "prognostic favorable (9.28e-4)" "unprognostic (8.46e-2)" "unprognostic (2.79e-3)" "unprognostic (6.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.16e-3)" "unprognostic (2.00e-2)" "unprognostic (1.08e-1)" "unprognostic (2.63e-3)" "unprognostic (4.25e-1)" "unprognostic (2.32e-1)" "unprognostic (4.68e-2)" "prognostic favorable (9.41e-5)" "unprognostic (9.21e-3)" "unprognostic (2.04e-1)" "unprognostic (7.06e-3)" "unprognostic (7.38e-2)" 37.6 10.3 9.7 17.2 9.7 58.4 26.5 27.7 13.2 21.7 9.8 14.6 16.1 23.1 7.8 19.7 13.6 20.4 16.3 9.5 12.5 20.0 25.4 26.4 19.8 14.0 11.5 14.4 22.7 18.5 11.4 33.3 14.7 11.2 11.9 18.8 11.4 10.8 14.3 30.3 17.2 22.9 9.5 33.0 14.4 11.1 13.2 40.5 27.3 21.6 14.7 19.8 21.7 8.7 8.4 5.0 9.1 8.8 26.6 9.5 8.7 8.8 14.8 9.4 9.1 6.9 11.8 13.2 6.8 11.2 6.2 5.3 10.7 18.9 9.6 15.1 8.8 15.0 9.1 8.1 13.8 17.1 16.1 10.5 12.7 10.6 17.9 9.5 126.0 14.9 6.7 14.9 8.7 4.4 17.3 15.0 10.1 4.6 22.6 11.7 6.7 14.0 24.2 14.1 6.4 13.4 7.7 8.1 11.1 7.9 5.5 21.4 74.1 8.2 8.3 9.5 10.4 23.7 18.3 11.0 5.8 20.1 12.0 9.4 4.2 7.6 9.5 7.5 13.0 3.6 8.3 9.6 4.0 3.6 12.1 13.1 27.7 11.0 7.1 1.2 9.7 9.7 9.7 9.7 27.7 13.2 9.5 12.5 14.0 11.5 14.7 9.5 13.2 8.7 88.4 32.1 24.1 30.0 29.0 52.8 10.3 6.4 12.5 52.1 9.7 8.6 17.7 15.7 15.0 16.5 16.7 7.7 57.6 37.0 11.7 10.9 50.4 23.3 16.2 84.2 10.8 10.3 21.6 8.9 3.2 16.4 12.8 19.8 14.5 8.9 98.6 25.2 13.7 30.3 43.2 10.7 12.2 24.8 19.0 7.5 12.5 26.5 23.2 34.7 21.9 16.3 65.9 24.6 10.7 11.2 20.6 11.7 27.3 12.7 25.2 12.2 19.2 18.3 124.9 31.3 49.1 11.1 16.2 13.7 51.3 8.2 61.2 9.5 11.1 18.0 SOCS2 "CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2" ENSG00000120833 "Suppressor of cytokine signaling 2" O14508 12 93569814-93583487 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 203.6;Hepatic stellate cells: 134.6" "Cancer enhanced" "Detected in all" "prostate cancer: 16.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 177.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 177.8" "Cell line enhanced" "Detected in many" "CACO-2: 192.0;K-562: 145.6;REH: 336.6;THP-1: 142.3" "Low region specificity" "Detected in all" CAB010356 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "CAB010356: AB_2239660" "unprognostic (4.16e-2)" "unprognostic (2.09e-1)" "unprognostic (1.10e-1)" "unprognostic (1.87e-1)" "unprognostic (9.67e-2)" "unprognostic (1.64e-2)" "prognostic favorable (1.09e-6)" "unprognostic (1.07e-1)" "unprognostic (1.49e-1)" "unprognostic (5.35e-3)" "prognostic favorable (8.17e-7)" "unprognostic (1.71e-1)" "unprognostic (1.67e-3)" "unprognostic (2.35e-2)" "unprognostic (1.51e-1)" "unprognostic (7.40e-2)" "unprognostic (9.09e-2)" 71.5 34.8 7.8 10.4 12.0 11.5 68.0 7.2 8.5 92.6 23.1 40.5 11.7 91.8 42.0 16.5 42.4 20.7 28.6 9.8 9.2 42.8 59.1 61.9 9.2 8.1 10.9 19.2 13.8 64.5 55.3 36.5 8.8 81.4 17.0 4.8 9.5 45.4 9.5 9.4 17.3 89.5 6.6 8.5 30.8 8.7 10.4 21.4 32.8 6.1 9.1 32.1 50.4 7.8 3.5 4.9 16.8 15.2 9.1 16.6 19.8 20.8 77.0 15.2 6.6 192.0 7.8 1.0 0.7 19.3 4.1 39.8 88.6 5.9 17.3 69.0 2.5 13.9 1.2 2.7 13.8 4.2 28.5 28.3 4.9 16.7 22.7 1.6 2.1 8.7 145.6 3.1 2.4 1.8 0.8 6.8 47.4 3.2 7.4 336.6 0.3 3.6 4.1 7.4 28.8 34.2 7.3 11.5 57.5 16.0 0.2 142.3 2.3 47.2 0.7 0.3 11.7 2.0 1.1 1.4 0.9 12.0 28.8 177.8 0.2 7.7 25.4 0.5 34.2 0.4 31.2 23.3 0.2 4.3 30.6 18.4 1.1 26.8 0.4 2.0 19.8 14.4 7.8 12.0 7.2 8.5 9.8 9.2 8.1 10.9 8.8 6.6 10.4 7.8 203.6 9.6 78.7 1.0 1.4 18.0 46.0 3.2 1.2 8.2 30.5 16.9 6.5 0.0 24.3 22.0 4.2 36.3 15.5 20.8 62.6 13.7 9.8 10.5 94.9 100.5 8.3 33.2 10.9 37.4 6.7 34.6 7.1 20.2 24.1 9.9 134.6 11.6 14.2 69.0 12.3 13.3 4.1 8.9 20.7 20.3 91.6 6.0 17.8 8.4 108.4 1.5 18.6 1.0 1.3 8.8 21.2 101.2 6.4 95.2 20.0 27.5 5.4 1.2 78.9 15.8 32.9 9.9 10.5 1.8 10.5 35.0 15.7 12.7 15.7 30.1 SPRED3 ENSG00000188766 "Sprouty related EVH1 domain containing 3" Q2MJR0 19 38388421-38399587 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.0;pituitary gland: 5.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 6.6;Enteroendocrine cells: 10.8;Excitatory neurons: 9.8;Inhibitory neurons: 10.4" "Cancer enhanced" "Detected in many" "glioma: 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 12.9;TIME: 15.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071521 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane" "HPA071521: " "unprognostic (1.09e-1)" "unprognostic (1.88e-3)" "unprognostic (8.71e-3)" "unprognostic (3.35e-3)" "unprognostic (3.70e-2)" "unprognostic (2.00e-3)" "unprognostic (2.09e-3)" "unprognostic (7.77e-3)" "unprognostic (1.49e-1)" "unprognostic (9.22e-3)" "unprognostic (1.69e-2)" "unprognostic (3.09e-2)" "unprognostic (1.40e-11)" "unprognostic (6.21e-4)" "unprognostic (3.67e-1)" "unprognostic (1.04e-3)" "unprognostic (8.45e-3)" 0.7 0.4 3.2 1.0 3.7 0.3 0.5 0.5 5.0 0.6 0.4 0.5 1.8 0.4 0.3 0.4 0.6 0.7 0.7 4.5 8.0 2.3 0.2 0.7 0.2 4.4 5.0 0.3 1.1 1.7 5.6 0.3 4.6 1.0 0.2 1.5 0.5 0.3 0.9 0.8 1.3 0.8 1.1 0.1 0.4 1.1 5.0 0.1 0.6 0.0 0.2 0.6 0.5 2.7 0.3 1.2 4.0 3.3 0.6 1.9 2.3 8.1 5.3 2.6 2.4 0.4 0.8 0.2 2.9 2.7 2.1 0.1 0.7 1.0 2.4 0.8 1.5 0.1 0.3 0.5 1.4 2.2 0.1 1.3 0.9 6.2 1.8 12.9 8.3 0.6 0.7 1.5 8.1 0.4 0.0 0.1 1.8 0.5 4.0 1.0 1.4 0.1 5.7 0.7 0.2 3.1 0.2 0.2 0.4 1.7 0.7 0.1 15.9 2.9 9.0 2.4 4.5 0.6 0.3 0.6 9.8 0.3 5.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 3.2 3.7 0.5 5.0 4.5 8.0 4.4 5.0 4.6 1.1 5.0 2.7 1.1 0.0 0.0 2.0 0.4 0.0 1.3 0.4 1.2 6.6 1.5 2.4 1.2 0.0 0.3 1.8 2.1 0.5 0.3 0.5 0.0 1.0 2.0 0.7 1.1 1.5 10.8 0.0 9.8 0.6 0.3 0.5 0.0 1.6 0.0 0.3 0.7 0.0 0.1 1.7 10.4 1.2 0.0 0.0 0.0 0.2 0.3 0.5 0.0 1.0 0.0 1.9 1.0 5.0 2.2 3.0 0.1 0.0 0.0 1.2 2.7 0.1 0.1 0.3 0.0 2.3 1.2 1.5 1.0 0.5 0.1 0.8 0.4 0.2 0.8 0.7 SPRY1 hSPRY1 ENSG00000164056 "Sprouty RTK signaling antagonist 1" O43609 4 123396795-123403760 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 238.1" "Cell type enhanced" "Detected in many" "Adipocytes: 771.3;Endothelial cells: 352.8;Fibroblasts: 222.3;Leydig cells: 448.0;Skeletal myocytes: 245.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 61.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 95.4;AN3-CA: 194.1;ASC diff: 76.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013538, HPA051369, HPA070554" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Cytosol" Nucleoplasm "CAB013538: AB_2533452, HPA051369: AB_2681457, HPA070554: AB_2686280" "unprognostic (1.27e-1)" "unprognostic (9.08e-2)" "unprognostic (2.06e-1)" "unprognostic (7.15e-2)" "unprognostic (5.33e-2)" "unprognostic (2.19e-2)" "unprognostic (1.36e-1)" "unprognostic (9.43e-2)" "unprognostic (6.99e-2)" "unprognostic (4.32e-1)" "unprognostic (4.06e-1)" "unprognostic (3.11e-2)" "unprognostic (8.77e-3)" "unprognostic (1.21e-3)" "unprognostic (4.48e-2)" "unprognostic (1.54e-2)" "unprognostic (1.27e-1)" 238.1 38.4 6.5 22.3 7.9 22.7 154.3 7.6 9.0 71.9 26.6 46.6 15.7 40.9 24.1 42.5 81.2 83.8 73.1 7.5 8.4 35.6 21.5 58.3 13.0 5.5 5.4 30.0 31.8 37.4 27.3 49.6 5.8 52.0 27.5 19.0 45.2 24.7 49.9 79.8 25.2 57.7 5.6 17.0 35.1 10.2 7.6 29.2 92.7 49.9 10.1 74.4 71.0 6.0 6.3 1.8 95.4 194.1 76.5 51.6 6.4 0.4 4.9 0.3 2.0 5.8 10.3 0.0 42.4 2.9 0.4 1.2 2.6 4.6 0.7 0.1 10.0 2.2 0.0 31.0 21.7 14.2 0.1 21.1 2.5 0.7 2.1 10.5 8.1 2.2 1.7 1.9 4.7 0.7 16.4 34.8 22.8 22.6 32.0 7.1 10.3 0.2 13.2 14.5 14.5 12.3 0.1 19.4 19.6 10.1 1.9 0.0 20.2 1.2 0.2 0.4 2.9 1.0 0.1 0.2 1.4 2.6 3.2 0.1 0.4 6.5 1.1 0.2 33.1 29.8 4.0 9.2 0.1 61.2 5.7 6.4 0.4 14.2 0.1 1.7 0.0 2.0 6.5 7.9 7.6 9.0 7.5 8.4 5.5 5.4 5.8 5.6 7.6 6.0 771.3 28.9 28.3 14.4 16.2 49.6 17.3 37.3 68.9 86.2 22.8 69.6 16.9 32.9 20.6 27.6 33.3 12.7 21.6 10.4 80.3 5.0 2.5 45.9 41.9 352.8 26.5 5.7 5.0 10.9 1.7 222.3 8.2 67.4 9.5 0.2 166.3 5.9 10.1 6.7 2.2 15.0 14.2 15.3 37.9 10.5 448.0 17.1 46.2 5.6 0.7 158.3 0.0 7.5 0.3 7.0 6.3 57.9 6.1 16.8 8.1 38.7 11.7 84.5 151.2 245.0 81.6 6.2 9.6 37.0 43.3 3.1 57.3 1.8 17.9 13.5 SRGAP1 "ARHGAP13, KIAA1304" ENSG00000196935 "SLIT-ROBO Rho GTPase activating protein 1" Q7Z6B7 12 63844700-64162217 "Disease related genes, Predicted intracellular proteins" "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 159.0;Early spermatids: 192.4;Microglial cells: 151.8;Muller glia cells: 136.2;Oligodendrocyte precursor cells: 159.8;Oligodendrocytes: 135.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 30.4;hTERT-HME1: 46.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052416, HPA078079" Uncertain Approved Cytosol NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 30: Epithelial cell lines - Translation" "Cluster 5: Muller glia cells - Visual perception" Cytosol "HPA052416: AB_2681824, HPA078079: " "unprognostic (3.05e-3)" "unprognostic (2.28e-1)" "unprognostic (1.58e-2)" "unprognostic (2.22e-3)" "unprognostic (2.24e-1)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (1.45e-3)" "unprognostic (1.43e-2)" "prognostic unfavorable (5.67e-4)" "unprognostic (3.54e-3)" "unprognostic (8.56e-2)" "unprognostic (1.41e-3)" "unprognostic (8.16e-2)" "unprognostic (2.08e-1)" "unprognostic (8.31e-2)" "unprognostic (1.56e-2)" 4.0 3.7 5.5 1.8 8.9 0.4 3.9 7.9 4.3 4.9 0.8 3.0 1.4 4.3 1.4 2.9 3.6 2.4 2.1 4.0 8.3 3.0 0.8 6.2 1.0 11.6 12.0 4.7 4.8 6.5 1.4 1.9 9.2 2.3 2.6 6.1 4.6 0.9 1.6 1.9 2.5 2.5 7.7 2.4 1.9 3.9 10.4 0.7 4.4 1.0 0.9 2.8 3.3 7.2 5.3 11.2 17.6 1.7 13.3 23.2 3.7 16.4 14.7 6.0 5.2 5.9 4.3 0.1 6.6 30.4 14.9 3.3 1.5 9.4 6.1 4.2 1.7 0.2 7.9 6.0 16.4 0.1 0.2 21.6 8.8 16.8 46.8 8.2 5.5 0.3 0.1 0.2 8.0 3.2 0.1 0.1 1.5 2.8 6.5 0.1 3.3 0.1 7.4 2.8 2.8 5.3 6.5 6.7 4.4 2.8 1.8 0.1 11.8 12.4 2.3 13.2 7.6 0.1 0.1 0.1 10.4 1.3 5.0 0.4 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.4 0.2 0.1 0.1 0.0 0.0 5.5 8.9 7.9 4.3 4.0 8.3 11.6 12.0 9.2 7.7 10.4 7.2 19.1 0.0 3.3 159.0 3.5 7.8 53.3 20.4 0.0 7.8 19.7 15.1 6.4 37.1 21.7 9.2 6.2 31.7 0.9 42.5 11.7 37.3 192.4 8.3 33.3 24.8 16.7 0.0 19.6 26.0 8.6 43.5 26.0 26.0 1.3 26.8 25.0 2.0 12.2 3.3 38.4 26.6 44.7 34.3 22.2 58.4 22.1 43.5 17.8 151.8 25.1 136.2 0.0 159.8 135.8 41.7 39.8 15.8 0.8 50.5 5.2 14.7 22.1 8.1 0.0 55.1 19.7 5.5 29.1 11.6 3.8 7.3 3.6 2.0 19.6 50.7 STOM "BND7, EPB7, EPB72" ENSG00000148175 Stomatin P27105 9 121338987-121370304 "Plasma proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 454.6;Erythroid cells: 535.1;Hepatocytes: 371.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 591.3;hTCEpi: 497.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010961, HPA011419" Approved Enhanced "Vesicles,Plasma membrane,Cytosol" NA NA 16000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 30: Epithelial cell lines - Translation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cytosol" "HPA010961: AB_1080111, HPA011419: AB_1080109" "unprognostic (1.11e-1)" "unprognostic (2.15e-2)" "unprognostic (5.27e-2)" "unprognostic (7.93e-2)" "unprognostic (5.68e-3)" "unprognostic (1.65e-2)" "unprognostic (9.20e-3)" "unprognostic (7.86e-2)" "unprognostic (1.76e-1)" "unprognostic (3.59e-2)" "unprognostic (3.32e-1)" "unprognostic (1.26e-1)" "unprognostic (5.23e-2)" "unprognostic (9.15e-3)" "unprognostic (2.27e-2)" "unprognostic (7.82e-2)" "unprognostic (2.99e-2)" 339.0 117.3 100.4 101.0 108.1 358.2 243.8 94.7 103.9 129.3 74.8 226.0 46.1 139.9 72.2 87.8 141.7 153.3 219.7 90.5 113.1 123.9 355.4 290.7 67.7 120.7 115.1 81.3 38.9 45.3 49.8 272.7 108.9 111.6 58.4 15.0 95.5 93.4 102.6 118.3 114.1 155.9 105.2 121.6 139.3 24.7 111.0 33.8 112.9 106.2 46.4 182.4 129.6 108.7 8.4 55.0 4.8 26.0 591.3 170.3 0.4 138.6 149.3 40.7 64.5 7.6 10.8 66.5 34.3 186.6 23.9 14.7 31.7 133.0 79.3 41.7 12.0 144.7 108.8 23.1 299.0 61.4 32.4 272.2 497.3 60.9 88.0 11.7 152.5 21.0 33.3 88.2 96.8 45.2 2.2 47.0 64.4 3.5 16.6 8.7 0.2 147.7 34.7 1.7 5.9 0.5 114.5 107.8 62.1 44.9 36.6 47.4 172.8 92.0 28.1 91.3 13.6 36.5 44.9 4.4 35.1 58.1 51.0 21.4 35.5 4.1 168.9 55.8 165.7 5.9 84.2 153.3 35.8 4.2 15.0 81.1 20.8 147.1 41.0 6.1 8.7 128.8 100.4 108.1 94.7 103.9 90.5 113.1 120.7 115.1 108.9 105.2 111.0 108.7 454.6 160.3 96.6 30.0 13.2 105.5 251.8 107.0 62.0 5.0 135.8 72.3 36.7 121.5 159.0 35.0 6.2 121.9 72.1 26.3 3.9 56.6 3.6 97.0 75.4 313.6 0.0 535.1 3.2 22.0 54.7 140.3 17.9 11.7 36.1 76.0 282.7 371.2 92.1 3.3 4.8 1.1 54.9 226.3 92.3 9.0 66.5 105.9 88.9 70.3 37.9 8.6 127.7 6.6 4.5 39.1 18.3 103.0 16.9 90.2 33.8 92.8 216.0 5.0 138.1 73.2 188.1 40.8 13.7 48.4 119.1 172.8 98.8 81.8 2.2 200.0 SV2B "HsT19680, KIAA0735" ENSG00000185518 "Synaptic vesicle glycoprotein 2B" Q7L1I2 15 91099950-91302565 "Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 24 "brain: 34.5;retina: 56.3" "Group enriched" "Detected in some" 5 "Bipolar cells: 137.1;Cone photoreceptor cells: 150.1;Excitatory neurons: 455.0;Rod photoreceptor cells: 139.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "RPMI-8226: 2.1;SCLC-21H: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046247 Approved NA NA "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA046247: AB_10963538" "unprognostic (2.92e-1)" "unprognostic (7.92e-2)" "unprognostic (1.32e-3)" "unprognostic (4.01e-5)" "unprognostic (2.66e-3)" "unprognostic (7.77e-2)" "unprognostic (3.36e-2)" "unprognostic (1.01e-1)" "unprognostic (3.57e-2)" "unprognostic (9.89e-2)" "unprognostic (1.20e-2)" "unprognostic (2.49e-1)" "unprognostic (1.39e-1)" "unprognostic (3.88e-2)" "unprognostic (1.66e-1)" "unprognostic (1.11e-2)" "unprognostic (3.10e-4)" 1.8 1.1 17.2 0.2 17.5 0.1 0.8 7.3 34.5 0.1 0.0 0.5 0.1 0.1 0.1 0.1 0.1 0.2 0.8 22.4 0.0 0.3 0.1 0.2 0.4 8.5 0.0 0.0 1.4 0.1 1.0 0.2 10.7 0.8 0.3 56.3 1.0 0.1 0.6 0.2 0.4 0.2 0.0 0.2 0.3 0.8 1.4 0.6 0.2 1.0 1.2 0.1 0.1 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 17.2 17.5 7.3 34.5 22.4 0.0 8.5 0.0 10.7 0.0 1.4 14.8 10.9 0.0 0.0 7.2 0.1 0.4 0.1 0.1 0.0 137.1 0.2 0.5 3.0 1.5 0.0 0.0 150.1 0.0 0.0 0.0 0.0 4.2 6.4 0.0 0.0 3.3 0.0 0.0 455.0 5.0 0.0 0.9 0.0 0.0 0.0 0.0 1.1 0.0 0.1 3.3 11.4 0.0 0.0 0.0 0.4 2.0 0.0 0.2 0.0 27.2 0.0 43.4 0.0 5.5 39.4 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 139.0 0.0 0.5 0.2 8.0 0.4 0.1 0.1 0.0 0.1 0.1 0.0 0.2 TACR1 "NK1R, NKIR, SPR, TAC1R" ENSG00000115353 "Tachykinin receptor 1" P25103 2 75046463-75199520 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.0" "Cell type enriched" "Detected in some" 7 "Inhibitory neurons: 83.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 23 "basophil: 2.2" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074573 Enhanced NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA074573: AB_2686701" "unprognostic (5.74e-4)" "unprognostic (2.41e-3)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.24e-1)" "unprognostic (8.62e-3)" "unprognostic (1.10e-1)" "unprognostic (3.33e-2)" "unprognostic (4.38e-2)" "unprognostic (1.46e-1)" "unprognostic (2.14e-3)" "unprognostic (1.63e-2)" "unprognostic (5.91e-4)" "unprognostic (1.03e-2)" "unprognostic (2.75e-1)" "unprognostic (1.06e-1)" "unprognostic (2.76e-2)" 6.2 0.3 1.7 0.7 3.6 0.0 5.0 0.0 7.2 4.9 0.0 1.0 0.2 3.0 0.7 1.2 2.9 1.1 0.1 0.6 3.7 0.7 0.0 0.8 1.3 2.2 4.3 0.6 0.1 0.2 0.1 0.5 10.0 1.5 0.5 1.0 1.5 1.0 0.3 4.0 0.7 2.7 0.8 0.0 0.5 0.0 2.5 1.1 0.5 0.3 1.3 2.0 2.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.6 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.6 0.0 7.2 0.6 3.7 2.2 4.3 10.0 0.8 2.5 0.9 7.6 0.0 0.0 1.0 0.0 2.5 0.0 0.0 0.0 1.0 0.3 0.3 1.4 0.0 0.0 0.0 2.1 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 11.8 0.0 0.0 4.5 0.0 0.2 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 83.2 0.2 0.0 0.0 2.6 0.9 0.0 0.0 7.2 2.8 0.0 0.4 0.0 3.5 4.2 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 3.3 0.0 0.2 0.2 0.0 0.0 0.1 1.8 0.1 0.1 0.0 0.0 0.2 TAL1 "bHLHa17, SCL, TCL5" ENSG00000162367 "TAL bHLH transcription factor 1, erythroid differentiation factor" P17542 1 47216290-47232220 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.4" "Cell type enriched" "Detected in some" 4 "Erythroid cells: 151.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 153.7;HMC-1: 70.6;HUVEC TERT2: 31.2;JURKAT: 60.0;K-562: 48.9;MOLT-4: 26.3;TIME: 34.4" "Region enriched" "Detected in many" 5 "midbrain: 14.3" "Low region specificity" "Detected in many" "CAB017805, HPA047866, HPA073983" Approved Enhanced Nucleoplasm Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "CAB017805: , HPA047866: AB_2680192, HPA073983: AB_2732246" "unprognostic (2.63e-1)" "unprognostic (2.62e-2)" "unprognostic (1.22e-1)" "unprognostic (2.40e-2)" "unprognostic (1.59e-1)" "unprognostic (8.80e-3)" "unprognostic (3.95e-3)" "unprognostic (1.33e-1)" "unprognostic (4.15e-2)" "unprognostic (1.99e-2)" "unprognostic (5.42e-3)" "unprognostic (3.68e-1)" "unprognostic (1.02e-2)" "unprognostic (2.76e-2)" "unprognostic (2.19e-1)" "unprognostic (1.51e-1)" "unprognostic (1.18e-2)" 7.5 2.5 4.9 1.0 4.5 29.4 6.3 4.7 4.4 2.9 3.0 2.1 0.8 2.9 0.6 1.8 3.5 2.3 5.9 4.6 4.6 4.4 1.5 13.0 1.4 6.5 7.1 1.2 0.9 0.9 1.7 6.9 6.8 2.1 1.3 0.2 1.1 0.8 2.1 1.7 3.1 2.7 6.9 7.1 1.8 0.9 6.4 0.4 5.4 2.5 0.7 2.4 2.5 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.2 0.1 153.7 0.0 0.0 0.0 0.0 70.6 0.0 0.0 0.0 0.0 0.0 31.2 60.0 48.9 0.1 0.0 0.0 26.3 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.1 34.4 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.5 4.9 4.5 4.7 4.4 4.6 4.6 6.5 7.1 6.8 6.9 6.4 6.8 23.9 0.0 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.1 0.1 3.7 1.5 1.3 1.8 0.0 0.1 0.0 0.0 0.0 0.1 5.3 0.0 0.1 18.1 0.0 151.5 0.0 0.0 0.3 0.6 0.0 0.0 36.8 0.0 26.7 0.1 10.6 0.0 0.1 0.0 0.0 1.6 1.5 18.2 0.0 4.8 1.8 29.0 0.8 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.4 1.3 0.4 0.1 1.0 0.0 2.0 0.0 0.0 0.0 TAMALIN GRASP ENSG00000161835 "Trafficking regulator and scaffold protein tamalin" Q7Z6J2 12 52006946-52015889 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 243.8;B-cells: 60.6;dendritic cells: 114.1;Macrophages: 60.6;Plasma cells: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 37.4;TIME: 27.4;WM-115: 50.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040664, HPA062028" Approved Approved "Nuclear bodies,Vesicles" No NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "Nuclear bodies" "HPA040664: AB_10794066, HPA062028: AB_2684664" "unprognostic (1.90e-1)" "unprognostic (1.29e-2)" "unprognostic (2.48e-2)" "unprognostic (2.39e-2)" "unprognostic (2.00e-2)" "unprognostic (2.38e-2)" "unprognostic (2.23e-2)" "unprognostic (1.93e-1)" "unprognostic (2.86e-1)" "unprognostic (8.71e-2)" "unprognostic (3.16e-3)" "unprognostic (7.20e-2)" "unprognostic (3.90e-3)" "unprognostic (1.99e-3)" "unprognostic (1.44e-1)" "unprognostic (3.53e-2)" "unprognostic (2.77e-2)" 31.9 6.3 9.8 4.1 14.9 23.8 26.9 3.2 21.5 17.6 0.4 9.4 2.2 22.0 1.6 7.1 22.2 9.6 24.2 10.5 3.7 12.2 4.2 46.8 3.8 5.0 4.9 14.9 5.7 2.8 6.2 8.9 4.8 13.0 1.9 0.1 6.5 3.1 10.6 10.7 9.8 6.0 4.1 18.2 8.6 2.6 7.6 3.7 16.3 8.4 2.3 12.5 17.1 7.1 0.0 0.0 4.4 0.2 1.9 3.6 1.0 0.2 1.1 0.0 1.1 0.0 0.0 0.0 10.0 0.0 0.4 0.1 1.3 0.0 0.4 0.2 1.3 0.3 0.0 6.2 7.4 0.3 3.3 7.2 0.0 0.3 0.0 0.0 37.4 1.0 1.6 0.0 0.9 0.2 3.1 10.5 4.0 0.0 0.2 0.1 0.8 0.0 0.0 0.0 1.1 1.6 0.0 0.2 7.5 2.7 0.0 0.3 27.4 0.0 2.5 0.2 0.0 0.2 0.0 0.1 0.6 0.0 50.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 9.8 14.9 3.2 21.5 10.5 3.7 5.0 4.9 4.8 4.1 7.6 7.1 243.8 0.0 0.0 0.0 60.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.2 114.1 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.2 5.8 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 60.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.3 5.4 0.0 0.0 0.0 TBC1D15 "DKFZp761D0223, FLJ12085" ENSG00000121749 "TBC1 domain family member 15" Q8TC07 12 71839707-71927248 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 160.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013388, HPA015592" Supported Supported Mitochondria,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Mitochondria, Cytosol" "HPA013388: AB_2199233, HPA015592: AB_1857789" "unprognostic (3.87e-2)" "prognostic favorable (7.06e-4)" "unprognostic (1.98e-1)" "unprognostic (1.60e-1)" "unprognostic (4.63e-2)" "unprognostic (6.13e-3)" "unprognostic (2.96e-2)" "unprognostic (3.10e-1)" "unprognostic (2.61e-1)" "unprognostic (1.02e-2)" "unprognostic (4.07e-2)" "unprognostic (2.18e-1)" "prognostic favorable (5.34e-4)" "unprognostic (5.73e-2)" "unprognostic (4.34e-2)" "unprognostic (2.31e-1)" "unprognostic (2.78e-1)" 28.4 25.9 9.9 15.7 13.2 42.2 25.4 11.8 17.0 21.0 8.4 15.5 15.5 21.3 13.0 16.3 15.1 21.6 15.3 9.4 11.1 22.6 30.6 21.4 22.5 13.2 12.4 22.3 23.8 23.0 14.3 23.4 13.2 17.8 14.9 14.1 22.6 13.0 43.4 18.1 17.8 18.3 11.3 21.8 17.2 18.5 10.5 24.9 27.9 25.5 19.8 17.8 14.9 18.5 21.0 20.3 17.1 18.4 35.2 38.8 25.6 20.8 58.5 30.6 39.7 13.9 18.4 26.9 14.0 21.6 21.9 13.7 22.3 15.7 32.6 23.1 18.0 23.5 17.0 12.3 29.9 33.1 17.1 35.0 20.5 23.1 39.3 39.7 26.9 25.7 27.9 16.0 25.4 15.3 24.9 25.3 37.4 19.2 17.4 17.9 19.1 29.3 23.3 18.6 18.9 17.3 29.5 25.9 26.2 23.7 26.5 23.1 25.3 23.9 10.6 26.5 14.4 38.1 36.1 35.5 14.3 22.6 21.8 2.6 5.7 7.8 6.1 5.5 6.8 4.3 7.5 5.8 5.1 4.2 9.5 8.6 11.7 5.7 8.1 2.8 10.8 5.4 9.9 13.2 11.8 17.0 9.4 11.1 13.2 12.4 13.2 11.3 10.5 18.5 83.4 48.1 69.3 42.4 34.7 58.6 33.6 23.8 25.6 33.7 30.2 25.5 24.8 24.3 38.5 18.4 10.4 20.4 43.1 18.3 13.7 29.3 160.8 38.1 40.4 53.3 13.8 27.8 60.3 25.5 15.5 44.5 17.3 82.0 34.1 30.8 79.2 35.6 24.0 52.2 57.7 22.0 20.3 54.2 41.8 26.7 34.8 46.0 32.0 35.6 27.5 29.9 16.5 45.2 85.7 25.1 11.0 32.7 33.9 39.9 21.5 39.8 49.8 25.6 19.7 58.2 35.7 76.9 24.5 18.1 68.5 38.3 39.2 38.8 15.0 37.1 TCAF2 "FAM115C, FAM139A, FLJ40722, GATD9" ENSG00000170379 "TRPM8 channel associated factor 2" A6NFQ2 7 143620952-143730409 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 16.2;Hepatocytes: 12.3;Syncytiotrophoblasts: 15.7;T-cells: 9.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 10.6;HUVEC TERT2: 11.6;TIME: 18.5;U-87 MG: 13.8" "HPA038756, HPA038758" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane, Cell Junctions" "HPA038756: AB_10960427, HPA038758: AB_10960353" "unprognostic (6.59e-2)" "unprognostic (4.99e-2)" "unprognostic (2.34e-2)" "unprognostic (8.86e-3)" "prognostic unfavorable (9.53e-5)" "unprognostic (1.89e-1)" "unprognostic (3.11e-2)" "unprognostic (4.47e-2)" "unprognostic (2.36e-1)" "unprognostic (2.04e-2)" "unprognostic (3.98e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (4.17e-6)" "unprognostic (7.19e-2)" "unprognostic (4.02e-2)" "unprognostic (5.41e-3)" "unprognostic (2.85e-2)" 2.1 1.9 1.5 4.0 1.5 4.1 5.8 4.6 3.4 4.0 0.0 1.2 1.0 1.7 0.8 9.2 1.9 2.2 1.2 1.5 1.9 2.6 4.5 3.7 4.2 2.2 2.5 2.6 2.0 2.1 2.6 5.2 2.5 2.8 1.1 3.2 3.7 1.2 0.7 4.3 2.4 1.5 0.7 2.8 2.0 1.6 1.7 3.3 1.3 0.7 3.4 2.8 5.9 3.2 5.5 0.3 0.1 0.2 1.0 1.0 2.0 1.5 3.1 0.7 2.2 0.1 0.3 0.2 2.1 1.3 0.5 0.8 0.1 3.0 2.3 10.6 0.5 0.8 0.6 0.1 1.2 0.3 0.4 2.9 1.3 0.3 0.9 2.1 11.6 0.7 3.0 5.1 4.3 0.8 0.6 0.8 0.2 5.0 2.7 0.4 2.1 2.4 0.0 1.9 0.1 0.1 0.5 4.3 0.2 0.8 1.9 0.2 18.5 1.3 0.9 5.5 0.4 7.7 2.6 0.1 13.8 0.4 3.2 5.7 0.2 0.2 2.9 0.2 3.1 1.9 4.8 3.1 0.2 1.8 4.2 3.3 0.9 2.2 0.2 0.7 5.6 1.2 1.5 1.5 4.6 3.4 1.5 1.9 2.2 2.5 2.5 0.7 1.7 3.2 0.5 0.0 1.8 0.0 4.5 0.0 1.3 0.0 3.4 0.7 5.6 3.4 0.4 0.0 1.8 0.0 0.0 16.2 5.6 0.2 0.0 0.9 1.0 0.8 1.4 3.5 0.0 0.4 3.7 0.4 4.9 2.4 2.6 1.3 2.5 0.3 0.7 12.3 2.0 0.0 3.6 0.2 0.0 1.6 0.0 1.1 1.8 1.8 0.0 0.0 0.4 2.1 7.2 1.5 0.1 1.3 0.1 0.7 5.0 2.1 2.1 0.4 0.0 0.1 0.0 2.3 1.1 3.5 2.0 4.9 0.0 15.7 9.1 0.8 0.4 1.1 TCF15 "bHLHa40, EC2, PARAXIS" ENSG00000125878 "Transcription factor 15" Q12870 20 603797-610398 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "heart muscle: 27.8;skeletal muscle: 13.2;tongue: 9.1" "Cell type enriched" "Detected in some" 6 "Adipocytes: 260.0" "Cancer enhanced" "Detected in many" "testis cancer: 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HEL: 10.6;HMC-1: 16.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA050998, HPA060221" Approved Supported "Nuclear speckles" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" "HPA050998: AB_2681302, HPA060221: AB_2684225" "unprognostic (2.12e-2)" "unprognostic (1.96e-2)" "unprognostic (1.58e-2)" "unprognostic (3.55e-2)" "unprognostic (1.29e-1)" "unprognostic (4.62e-2)" "unprognostic (5.57e-2)" "unprognostic (2.33e-1)" "unprognostic (2.81e-1)" "prognostic unfavorable (3.25e-4)" "unprognostic (1.52e-1)" "unprognostic (9.43e-2)" "unprognostic (1.27e-3)" "unprognostic (7.21e-2)" "unprognostic (8.56e-2)" "unprognostic (5.11e-1)" "unprognostic (6.99e-2)" 7.0 0.6 1.3 0.1 1.2 0.0 4.6 1.2 1.4 0.2 0.9 1.6 0.1 0.8 0.0 0.3 0.4 0.1 27.8 1.1 1.2 1.5 0.2 0.6 0.1 1.3 1.3 0.2 0.3 0.1 0.4 3.3 1.4 0.3 0.0 0.0 0.6 0.0 13.2 0.2 0.5 0.2 1.3 0.0 0.6 2.0 1.3 0.0 0.5 9.1 0.0 0.9 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 2.9 10.6 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 1.5 0.0 1.3 0.0 3.0 0.0 1.4 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 1.2 1.4 1.1 1.2 1.3 1.3 1.4 1.3 1.3 1.2 260.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.6 0.5 0.6 1.0 15.6 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.7 0.2 0.2 41.2 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.6 0.0 0.1 7.1 0.0 0.1 1.7 0.5 0.0 0.0 0.0 0.4 0.2 0.0 0.5 0.0 2.8 0.0 0.1 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 13.1 3.7 23.3 2.3 0.6 0.0 0.0 0.0 0.2 0.5 0.0 0.0 TCF4 "bHLHb19, E2-2, ITF2, SEF2-1B" ENSG00000196628 "Transcription factor 4" P15884 18 55222185-55664787 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Corneal dystrophy, Disease variant, Epilepsy, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.1" "Cell type enhanced" "Detected in many" "Adipocytes: 820.0;Endothelial cells: 574.5;Inhibitory neurons: 1177.6;Oligodendrocyte precursor cells: 719.8;Oligodendrocytes: 573.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 65.1" "Group enriched" "Detected in many" 14 "memory B-cell: 173.6;naive B-cell: 146.8;plasmacytoid DC: 559.8" "Group enriched" "Detected in many" 33 "B-cells: 173.6;dendritic cells: 559.8" "Cell line enhanced" "Detected in many" "HDLM-2: 140.4;SH-SY5Y: 157.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020722, HPA025958" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "CAB020722: , HPA025958: AB_1857849" "unprognostic (2.11e-1)" "unprognostic (9.10e-2)" "unprognostic (8.69e-2)" "unprognostic (7.89e-3)" "unprognostic (1.42e-1)" "unprognostic (1.36e-3)" "unprognostic (3.03e-2)" "unprognostic (8.64e-2)" "unprognostic (1.79e-2)" "unprognostic (3.29e-2)" "unprognostic (2.77e-1)" "unprognostic (8.44e-2)" "prognostic unfavorable (7.24e-5)" "unprognostic (1.99e-3)" "unprognostic (2.68e-2)" "unprognostic (2.76e-3)" "prognostic unfavorable (9.95e-4)" 20.3 9.6 3.7 12.8 12.5 9.5 11.6 65.1 26.5 28.5 0.0 7.4 5.1 23.0 2.1 9.7 13.4 17.4 17.5 29.8 0.0 4.4 4.4 15.5 14.7 5.5 1.0 25.9 5.8 8.0 6.5 28.9 3.9 6.6 7.9 14.0 6.8 10.2 6.1 6.4 5.0 24.1 2.2 13.1 6.0 15.4 2.4 9.8 13.3 16.7 14.7 13.1 7.3 14.4 0.1 4.1 36.8 11.4 8.5 14.4 0.1 18.4 40.6 13.2 17.2 23.1 3.6 28.8 0.1 41.9 2.7 4.5 17.9 17.1 9.2 140.4 13.9 12.1 0.1 0.0 4.0 5.3 2.8 19.6 5.3 18.5 0.7 9.1 45.8 1.6 19.5 22.0 11.0 0.0 7.6 0.0 10.4 0.1 2.4 41.6 14.9 65.4 0.0 0.9 12.6 157.7 0.0 1.5 0.0 11.1 1.6 1.3 49.1 48.5 17.4 2.1 14.6 16.3 32.2 25.7 11.0 5.2 15.5 0.9 7.4 0.8 0.9 8.3 0.7 173.6 0.2 0.5 20.6 146.8 0.5 0.3 1.8 11.2 7.4 559.8 0.7 11.3 3.7 12.5 65.1 26.5 29.8 0.0 5.5 1.0 3.9 2.2 2.4 14.4 820.0 6.4 13.1 501.1 217.4 117.0 37.8 34.0 80.8 293.0 6.5 23.4 35.5 4.3 32.6 22.0 83.4 1.8 446.8 0.1 0.0 1.5 103.2 17.5 201.4 574.5 5.4 34.2 503.8 7.1 1.5 296.7 1.5 12.2 13.9 105.7 316.3 6.6 39.6 25.2 1177.6 0.3 26.4 112.4 129.2 116.3 205.3 80.4 64.0 474.1 32.7 372.8 13.4 719.8 573.6 2.1 0.1 182.1 131.7 20.8 0.0 2.3 25.9 54.7 236.7 304.5 221.0 8.7 14.5 47.5 84.4 2.6 15.1 164.8 0.2 17.8 TEAD2 "ETF, TEF-4, TEF4" ENSG00000074219 "TEA domain transcription factor 2" Q15562 19 49340595-49362457 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 51.1;Early spermatids: 76.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 22 "memory B-cell: 1.7;naive B-cell: 2.7" "Lineage enriched" "Detected in single" 27 "B-cells: 2.7" "Cell line enhanced" "Detected in many" "AF22: 135.3;AN3-CA: 147.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066292, HPA069963" Supported Nucleoplasm NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "HPA066292: AB_2685651, HPA069963: AB_2686222" "unprognostic (2.69e-2)" "unprognostic (1.08e-1)" "unprognostic (2.09e-1)" "unprognostic (1.03e-2)" "unprognostic (8.58e-3)" "unprognostic (4.39e-1)" "prognostic unfavorable (8.66e-4)" "unprognostic (2.91e-1)" "unprognostic (4.47e-3)" "unprognostic (1.11e-1)" "unprognostic (3.96e-3)" "unprognostic (1.24e-1)" "unprognostic (4.39e-2)" "unprognostic (2.39e-2)" "unprognostic (1.08e-1)" "unprognostic (1.31e-1)" "unprognostic (6.78e-2)" 32.8 17.8 7.5 15.4 7.1 0.2 31.6 6.6 7.9 41.8 16.2 50.4 7.6 39.6 12.4 11.0 34.2 15.5 55.5 7.5 6.8 34.5 11.9 35.7 9.0 8.7 8.3 33.5 26.8 19.4 9.2 17.7 7.7 26.5 11.2 3.4 18.5 22.7 12.9 10.7 18.5 38.4 7.6 14.8 31.3 26.6 8.3 3.1 16.9 22.1 7.3 27.2 24.4 6.6 12.5 28.6 135.3 147.6 14.2 20.8 24.3 22.8 23.9 25.6 29.7 2.3 6.8 1.2 29.6 38.5 13.1 13.9 37.5 7.7 14.1 0.1 17.5 0.0 27.2 19.3 24.6 0.1 0.3 24.8 17.8 17.4 8.4 50.6 92.1 0.1 22.0 0.0 36.1 15.3 0.0 0.2 45.4 35.2 36.2 0.0 40.8 0.2 23.3 0.2 0.2 82.0 38.1 5.6 10.1 46.1 40.5 3.5 55.0 45.9 28.1 9.9 1.8 0.1 0.1 4.8 1.7 0.6 18.3 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 7.1 6.6 7.9 7.5 6.8 8.7 8.3 7.7 7.6 8.3 6.6 26.1 3.2 3.2 0.0 3.8 3.3 6.9 5.9 8.6 0.4 21.1 9.5 1.0 8.6 3.4 12.9 0.0 0.6 0.4 1.3 1.9 51.1 76.6 7.3 20.7 29.5 7.1 3.2 0.1 26.2 23.7 15.0 9.7 6.5 0.0 14.7 21.4 2.8 0.6 0.0 0.1 6.6 8.2 0.9 3.6 29.6 15.2 0.7 5.4 1.9 0.0 15.9 0.0 0.0 0.1 22.7 4.9 22.2 0.1 7.2 0.1 0.2 1.2 0.4 32.9 7.6 28.7 2.1 2.4 2.0 1.6 1.2 0.5 4.4 6.8 2.8 TEK "CD202b, TIE-2, TIE2, VMCM, VMCM1" ENSG00000120156 "TEK receptor tyrosine kinase" Q02763 9 27109141-27230174 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 46.3" "Group enriched" "Detected in many" 10 "Adipocytes: 70.8;Endothelial cells: 73.9;Hepatic stellate cells: 122.0;Microglial cells: 38.4;Oligodendrocyte precursor cells: 137.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 90.9;NTERA-2: 45.2;TIME: 99.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010359, HPA073265" Approved Supported "Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 7750000 13000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Centriolar satellite" "CAB010359: AB_2203226, HPA073265: AB_2686592" "unprognostic (2.24e-1)" "unprognostic (1.74e-1)" "unprognostic (5.55e-2)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" "prognostic favorable (2.31e-5)" "unprognostic (7.48e-2)" "unprognostic (1.72e-2)" "unprognostic (1.41e-1)" "unprognostic (5.58e-2)" "unprognostic (2.72e-1)" "prognostic favorable (7.81e-4)" "unprognostic (7.50e-3)" "unprognostic (6.87e-3)" "unprognostic (1.83e-1)" "unprognostic (5.24e-3)" 20.1 9.1 8.1 5.8 7.0 0.2 14.0 6.1 8.4 9.3 4.3 5.0 3.7 12.4 2.3 5.3 6.7 11.2 16.8 7.1 6.8 23.0 10.5 28.8 3.7 7.2 6.6 3.5 3.5 4.4 3.0 46.3 7.6 3.8 5.4 0.7 3.1 6.2 10.5 2.8 5.5 12.7 6.8 28.8 4.0 1.4 9.4 1.8 9.1 22.9 2.8 6.9 3.9 6.8 0.3 0.0 3.5 0.0 0.4 5.6 0.1 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 2.4 0.0 1.6 0.0 0.0 1.8 0.0 2.2 0.8 0.1 90.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 45.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 18.3 0.0 0.0 99.1 0.0 0.5 9.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.1 8.4 7.1 6.8 7.2 6.6 7.6 6.8 9.4 6.8 70.8 3.2 1.3 1.3 0.4 1.5 0.0 0.0 0.0 0.0 0.3 0.5 8.6 0.0 0.6 1.8 0.0 0.4 0.4 0.0 0.0 0.0 0.6 0.6 0.8 73.9 0.0 2.7 4.3 0.0 2.8 4.2 0.0 0.7 0.0 0.3 122.0 1.3 0.3 0.0 5.0 0.0 0.0 6.7 2.2 0.9 0.6 0.4 0.0 38.4 0.0 0.1 0.0 137.7 2.1 1.3 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.2 0.0 1.6 1.9 0.1 0.4 0.3 1.3 1.4 0.5 1.8 0.0 0.0 TGFBR2 "MFS2, TBR-ii, TBRII" ENSG00000163513 "Transforming growth factor beta receptor 2" P37173 3 30606601-30694142 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Cancer-related genes, Craniosynostosis, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 391.5;Endothelial cells: 236.4;Hepatic stellate cells: 478.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 313.6;ASC TERT1: 472.3;HSkMC: 430.0;LHCN-M2: 381.7;TIME: 418.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB073537 Supported "Plasma membrane" NA NA 810000 "Cluster 5: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB073537: " "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (3.70e-1)" "unprognostic (3.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (7.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.65e-2)" "unprognostic (4.72e-2)" "unprognostic (1.81e-2)" "unprognostic (8.81e-2)" "unprognostic (8.02e-2)" 230.0 56.1 16.5 73.8 12.9 29.4 145.7 13.8 19.3 90.0 30.6 96.0 44.2 69.1 18.2 44.9 69.6 91.9 95.2 10.6 13.4 67.9 59.1 148.0 70.1 17.6 16.5 26.6 52.0 59.0 16.9 81.6 16.7 44.1 54.1 2.1 49.2 60.8 31.1 39.1 77.7 107.2 17.3 111.1 63.4 7.8 21.5 49.7 91.8 62.2 60.7 98.0 55.1 17.2 16.6 100.2 5.3 0.1 313.6 472.3 15.9 83.9 116.1 28.5 27.7 22.9 86.6 2.2 298.2 117.2 32.2 33.3 4.0 125.4 42.0 7.0 8.9 10.1 10.7 104.5 128.5 14.9 76.6 430.0 93.6 126.3 114.4 117.0 296.0 10.9 1.8 0.0 381.7 1.3 16.2 10.5 2.2 75.7 39.8 14.1 36.4 2.1 113.5 40.5 0.1 5.6 24.9 6.1 22.0 6.6 0.0 14.0 418.6 134.7 33.2 61.4 32.0 2.8 0.3 12.5 80.1 16.1 55.8 9.0 3.0 11.5 3.4 3.1 3.3 4.5 4.8 3.3 2.6 6.4 16.6 7.3 13.1 1.9 8.0 6.6 0.7 3.8 16.5 12.9 13.8 19.3 10.6 13.4 17.6 16.5 16.7 17.3 21.5 17.2 391.5 144.2 99.7 0.7 77.0 37.3 18.9 23.5 39.9 5.1 23.7 24.1 84.5 50.1 39.5 27.6 0.0 6.8 85.3 10.5 3.9 13.1 2.5 28.3 57.5 236.4 8.4 20.4 0.4 15.8 5.1 129.2 39.3 30.8 29.8 0.7 478.0 55.5 30.4 0.0 1.0 12.4 22.4 147.0 58.0 3.8 32.9 67.9 30.2 170.5 47.5 0.2 56.7 6.0 2.4 37.6 12.1 47.4 37.5 8.6 13.6 7.2 14.7 1.2 32.9 60.8 53.4 0.3 1.2 8.0 30.5 3.7 68.2 1.7 14.5 10.8 TLL1 ENSG00000038295 "Tolloid like 1" O43897 4 165873237-166104457 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Differentiation "Developmental protein, Hydrolase, Metalloprotease, Protease" "Atrial septal defect, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 20.0;placenta: 6.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 115.1" "Cancer enhanced" "Detected in some" "renal cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 6.0;Karpas-707: 9.6;PC-3: 3.3" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 8 "cerebellum: 45.8" HPA060767 Approved Vesicles "Secreted to extracellular matrix" NA NA 560000 "Cluster 6: Brain - Smell perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA060767: AB_2684357" "unprognostic (2.17e-1)" "unprognostic (6.45e-4)" "unprognostic (8.60e-2)" "unprognostic (2.65e-5)" "unprognostic (9.85e-2)" "unprognostic (2.51e-4)" "unprognostic (3.37e-2)" "unprognostic (3.61e-2)" "unprognostic (1.56e-1)" "unprognostic (5.07e-4)" "unprognostic (2.86e-2)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (2.13e-3)" "unprognostic (7.76e-2)" "unprognostic (6.91e-3)" "unprognostic (1.21e-5)" 3.1 0.5 0.7 1.0 5.9 0.0 2.7 20.0 8.9 1.8 0.0 1.2 0.6 1.1 0.3 0.7 1.3 2.4 0.7 9.9 5.4 1.6 0.1 1.2 1.0 3.5 6.9 0.3 2.3 0.8 0.9 6.4 4.4 0.9 0.9 1.8 0.8 0.8 0.4 1.4 1.8 1.4 0.0 0.0 0.7 0.4 3.0 0.3 1.4 0.4 0.8 1.6 1.5 1.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.3 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 1.3 0.0 0.9 0.0 0.0 9.6 0.0 0.0 0.0 0.1 0.9 0.0 3.3 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 5.9 20.0 8.9 9.9 5.4 3.5 6.9 4.4 0.0 3.0 1.1 10.2 0.0 0.6 0.0 0.0 1.8 0.3 1.3 0.6 14.1 0.2 0.1 7.1 1.5 1.8 0.0 0.0 4.4 0.0 0.0 0.0 1.5 0.1 0.0 2.0 18.9 0.0 0.0 24.9 2.0 1.4 2.4 0.0 0.1 0.0 0.0 2.5 0.0 0.3 8.4 8.0 0.1 0.0 0.0 1.0 0.0 3.1 0.1 1.8 10.3 0.0 0.1 0.0 115.1 0.5 0.1 0.0 4.5 0.0 1.1 4.0 1.1 0.8 0.7 0.0 0.2 0.3 0.1 0.2 0.1 1.7 1.9 0.8 0.0 0.6 0.2 TLR4 "ARMD10, CD284, hToll, TLR-4" ENSG00000136869 "Toll like receptor 4" O00206 9 117704175-117724735 "CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Age-related macular degeneration, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 38.6;Astrocytes: 50.9;Hepatic stellate cells: 62.8;Hofbauer cells: 38.2;Kupffer cells: 106.0;Macrophages: 64.5;monocytes: 54.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 86.8" "Group enriched" "Detected in many" 33 "dendritic cells: 22.4;granulocytes: 86.8;monocytes: 65.6" "Cell line enhanced" "Detected in many" "Karpas-707: 60.0;TIME: 43.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004025, HPA049174" Approved Supported "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Golgi apparatus" "CAB004025: , HPA049174: AB_2680662" "unprognostic (1.60e-1)" "unprognostic (8.34e-2)" "unprognostic (7.22e-2)" "prognostic favorable (6.29e-4)" "unprognostic (3.39e-1)" "unprognostic (7.48e-2)" "unprognostic (8.68e-2)" "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "unprognostic (5.18e-2)" "unprognostic (8.00e-2)" "unprognostic (9.42e-2)" "unprognostic (4.08e-2)" "unprognostic (8.63e-2)" "prognostic unfavorable (3.79e-4)" "unprognostic (1.09e-2)" "unprognostic (1.96e-2)" 31.1 11.0 12.4 25.7 15.7 22.3 12.0 11.7 8.3 6.5 1.7 6.7 4.3 5.6 1.2 4.8 4.8 10.8 8.4 10.3 17.8 6.8 16.7 16.2 13.1 12.3 14.0 6.0 2.6 2.5 2.1 23.9 12.4 4.6 7.3 2.9 6.0 3.2 3.1 3.5 5.8 10.8 14.9 32.6 4.4 1.5 14.2 3.5 5.5 12.0 7.7 13.3 2.7 10.1 0.0 0.0 25.5 0.0 11.1 23.0 0.1 10.2 17.9 2.5 1.5 0.0 2.6 3.6 0.5 26.7 7.5 0.1 0.0 2.2 3.7 0.0 0.0 5.7 5.1 0.4 8.1 19.1 0.1 14.2 0.0 5.4 0.7 22.5 31.4 0.0 0.0 60.0 29.2 0.0 0.0 2.9 3.1 2.4 1.2 0.0 28.0 19.8 0.9 28.9 0.0 0.1 6.4 0.0 1.0 2.2 0.0 10.4 43.5 1.4 18.4 0.1 4.8 0.0 0.0 0.0 0.9 19.1 15.2 64.0 64.9 21.5 0.1 57.5 0.0 1.7 0.1 0.0 22.4 0.5 0.0 0.0 86.8 0.1 65.6 0.9 0.0 25.5 12.4 15.7 11.7 8.3 10.3 17.8 12.3 14.0 12.4 14.9 14.2 10.1 38.6 0.0 5.0 50.9 2.3 0.8 0.3 0.1 0.6 0.2 3.5 1.0 2.9 2.8 2.9 0.0 0.0 0.3 0.1 1.6 0.0 0.1 0.1 3.5 29.2 31.6 0.0 1.3 0.2 0.2 0.2 11.5 1.5 6.8 15.8 1.2 62.8 1.9 38.2 0.0 0.2 2.0 0.0 106.0 8.6 0.4 0.0 64.5 1.8 26.2 54.0 8.8 2.1 7.5 0.3 0.5 6.1 0.0 0.1 0.1 0.0 0.4 3.7 1.3 6.6 5.5 4.5 0.1 0.3 0.3 0.0 0.8 0.9 3.1 1.2 3.3 TMEM132A "FLJ20539, GBP, HSPA5BP1" ENSG00000006118 "Transmembrane protein 132A" Q24JP5 11 60924460-60937159 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 187.8;choroid plexus: 117.3" "Cell type enhanced" "Detected in many" "Astrocytes: 82.3;Ductal cells: 80.0;Horizontal cells: 254.1;Muller glia cells: 188.8;Rod photoreceptor cells: 165.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 174.1;MCF7: 177.8;SK-BR-3: 176.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051979, HPA060492" Enhanced Supported Approved Mitochondria No No 4100000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 38: EFO-21 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Mitochondria "HPA051979: AB_2681681, HPA060492: " "unprognostic (2.52e-2)" "unprognostic (2.01e-1)" "unprognostic (3.75e-2)" "prognostic favorable (1.98e-5)" "unprognostic (7.94e-3)" "unprognostic (3.74e-1)" "unprognostic (4.42e-3)" "unprognostic (2.39e-2)" "unprognostic (1.99e-1)" "unprognostic (1.30e-1)" "unprognostic (2.88e-1)" "unprognostic (5.98e-2)" "prognostic unfavorable (1.55e-9)" "unprognostic (3.31e-1)" "unprognostic (9.74e-2)" "unprognostic (1.50e-1)" "unprognostic (8.41e-3)" 7.7 21.0 137.9 8.6 134.3 0.3 7.7 119.4 187.8 12.0 117.3 5.5 2.5 13.6 1.2 19.5 4.8 5.5 13.7 134.1 136.9 13.9 2.1 10.1 1.7 154.5 131.2 18.8 6.8 12.4 23.6 16.6 126.4 9.4 1.0 28.1 25.9 1.8 3.9 6.1 6.0 3.7 123.0 5.7 32.4 6.7 144.6 1.3 4.8 3.1 5.4 4.2 9.2 114.7 37.0 50.7 44.1 88.0 3.6 1.7 78.1 27.0 84.5 24.6 20.3 18.0 33.3 0.3 174.1 7.8 79.9 67.6 10.3 46.0 9.5 0.5 14.8 1.1 33.3 32.7 30.8 0.5 1.3 7.7 8.6 45.8 7.1 38.7 42.1 7.0 2.3 2.3 7.8 177.8 0.9 0.2 58.5 1.2 26.9 0.4 18.6 4.2 36.4 18.7 43.7 104.1 19.3 176.4 16.7 22.3 123.7 0.6 49.4 9.5 43.2 2.7 52.3 0.4 0.3 2.1 78.5 0.1 46.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 137.9 134.3 119.4 187.8 134.1 136.9 154.5 131.2 126.4 123.0 144.6 114.7 11.8 0.0 0.0 82.3 0.6 1.3 2.7 56.2 5.7 62.8 17.1 11.7 0.8 4.3 22.2 5.5 18.8 31.4 0.1 0.7 1.9 80.0 0.5 12.4 7.0 11.9 15.6 0.0 22.6 13.3 28.7 7.7 9.2 27.7 0.0 57.5 11.4 0.0 3.3 254.1 29.1 2.7 20.3 0.3 1.0 1.0 1.8 0.7 0.0 7.5 3.1 188.8 0.0 12.1 3.3 63.2 1.6 3.4 0.0 9.7 0.0 0.4 4.0 165.3 6.6 4.4 15.2 1.2 4.0 5.7 0.9 27.1 0.3 19.2 2.3 7.2 TMPRSS5 "MGC141886, MGC148044" ENSG00000166682 "Transmembrane serine protease 5" Q9H3S3 11 113687547-113706373 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.6;choroid plexus: 20.8" "Cell type enhanced" "Detected in some" "Astrocytes: 26.4;Excitatory neurons: 5.4;Horizontal cells: 5.0;Oligodendrocytes: 15.5" "Cancer enhanced" "Detected in some" "glioma: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.0;CAPAN-2: 3.2;OE19: 2.0;WM-115: 2.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010992 Approved Nucleoplasm NA NA "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA010992: AB_1858152" "unprognostic (1.53e-2)" "unprognostic (3.81e-2)" "unprognostic (2.97e-1)" "unprognostic (1.05e-1)" "unprognostic (1.93e-1)" "unprognostic (8.73e-2)" "unprognostic (2.99e-3)" "unprognostic (3.08e-1)" "unprognostic (5.19e-3)" "unprognostic (8.49e-2)" "unprognostic (8.13e-2)" "unprognostic (3.38e-2)" "unprognostic (1.96e-3)" "unprognostic (1.18e-1)" "unprognostic (1.75e-1)" "unprognostic (1.80e-1)" "unprognostic (4.04e-3)" 1.3 0.5 28.1 0.2 34.7 1.4 2.0 24.9 39.0 0.8 20.8 0.7 0.1 0.5 0.2 0.5 0.7 0.7 1.0 28.2 27.0 1.0 1.0 0.7 0.2 34.0 29.8 0.6 0.5 0.0 1.6 0.2 33.1 0.8 0.3 1.1 9.6 0.3 2.6 2.1 0.7 0.3 28.5 0.8 0.8 2.1 32.1 0.3 0.6 0.5 0.3 0.7 1.0 50.6 0.2 0.3 2.0 1.1 0.2 0.1 0.3 0.5 0.2 0.3 0.4 1.1 3.2 0.1 1.4 0.2 0.3 0.4 0.1 0.2 0.1 0.2 0.6 0.4 0.3 0.0 0.1 0.5 0.4 0.2 0.2 0.2 0.5 0.2 0.3 0.7 0.4 0.2 0.4 0.0 0.4 0.6 0.2 2.0 0.1 0.4 0.2 0.0 0.3 0.2 0.3 0.4 0.2 0.0 1.6 0.2 0.2 0.2 0.2 0.4 0.7 0.3 0.3 0.2 0.1 0.0 0.1 0.4 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 34.7 24.9 39.0 28.2 27.0 34.0 29.8 33.1 28.5 32.1 50.6 0.2 0.0 0.0 26.4 0.2 0.3 0.2 0.0 0.0 0.5 1.0 0.9 0.5 0.0 0.1 1.8 2.1 0.0 0.2 0.2 0.0 0.3 0.1 0.3 0.2 0.3 0.0 1.3 5.4 0.9 0.0 0.3 0.0 0.4 0.0 0.4 0.4 0.2 0.1 5.0 2.8 0.0 0.0 0.0 0.3 0.3 0.3 0.1 0.0 2.8 0.1 3.2 0.0 3.5 15.5 0.6 0.0 0.0 0.3 0.2 0.0 0.0 0.1 1.3 0.0 0.5 0.1 1.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.2 TOX2 "C20orf100, dJ1108D11.2, GCX-1" ENSG00000124191 "TOX high mobility group box family member 2" Q96NM4 20 43914852-44069616 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 50.2" "Cell type enhanced" "Detected in many" "Early spermatids: 22.3;Excitatory neurons: 20.5;Hepatic stellate cells: 34.2;Inhibitory neurons: 76.9;Oligodendrocyte precursor cells: 45.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 6.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 92.0;U-266/70: 57.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA049900, HPA058396" Approved Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA049900: AB_2680942, HPA058396: AB_2683704" "unprognostic (2.15e-2)" "unprognostic (1.82e-2)" "unprognostic (8.97e-3)" "prognostic unfavorable (2.60e-4)" "unprognostic (1.33e-1)" "unprognostic (1.01e-1)" "unprognostic (7.53e-3)" "unprognostic (6.29e-2)" "unprognostic (1.66e-1)" "unprognostic (1.86e-1)" "unprognostic (1.75e-2)" "unprognostic (2.78e-2)" "prognostic unfavorable (7.45e-8)" "unprognostic (1.60e-1)" "unprognostic (2.00e-1)" "unprognostic (7.60e-2)" "unprognostic (3.12e-1)" 10.0 4.0 11.2 6.2 8.2 1.8 6.8 4.9 18.4 10.2 2.3 7.6 1.3 6.2 1.1 12.8 3.6 2.9 3.6 8.3 35.7 5.1 5.2 36.4 13.3 12.3 18.8 3.1 2.0 10.1 24.6 2.6 15.9 16.7 2.4 1.9 3.8 2.7 1.5 5.1 10.2 1.6 5.8 5.7 9.7 20.8 25.9 50.2 7.4 6.4 8.1 17.6 8.9 10.6 9.9 12.5 4.9 0.9 4.7 13.3 0.1 11.5 5.3 8.1 8.9 0.0 4.0 0.0 16.8 16.6 35.2 5.1 3.2 0.3 8.4 15.5 2.7 0.0 1.1 0.0 92.0 0.1 19.4 31.0 14.0 27.0 1.6 25.8 9.4 9.5 0.0 14.5 4.6 11.3 3.2 4.5 3.0 0.3 42.2 0.0 10.1 15.4 0.0 1.2 4.3 35.8 2.4 0.0 18.0 0.5 0.0 9.2 11.3 0.0 7.5 0.3 0.1 57.4 13.5 9.0 16.9 0.1 27.0 0.0 0.2 6.5 0.0 0.1 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.7 1.1 0.0 2.6 1.2 0.1 11.2 8.2 4.9 18.4 8.3 35.7 12.3 18.8 15.9 5.8 25.9 10.6 8.0 0.0 0.6 3.9 3.4 1.0 1.0 0.7 0.0 0.8 0.2 0.1 0.8 1.5 0.1 0.0 0.0 0.0 7.3 0.3 0.0 0.1 22.3 0.3 8.9 8.9 0.0 0.0 20.5 0.2 0.1 6.7 1.5 0.3 0.0 10.7 34.2 0.5 1.5 3.3 76.9 0.6 0.0 2.9 3.6 17.3 1.8 1.2 1.8 3.7 0.2 4.6 1.0 45.2 0.5 0.1 2.2 0.7 12.1 0.5 0.0 0.1 0.0 0.1 0.0 0.4 8.7 1.3 1.8 0.2 1.3 0.3 10.5 0.1 1.8 0.3 TUBB6 "HsT1601, MGC4083" ENSG00000176014 "Tubulin beta 6 class V" Q9BUF5 18 12307669-12344320 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 190.2;Extravillous trophoblasts: 494.3;Pancreatic endocrine cells: 221.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 157.3" "Group enriched" "Detected in many" 6 "B-cells: 58.7;dendritic cells: 157.3" "Cell line enhanced" "Detected in many" "TIME: 821.6" "Region enriched" "Detected in many" 6 "olfactory bulb: 19.9" "Region enhanced" "Detected in all" "spinal cord: 10.3" "HPA043640, HPA046280" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes 52000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (4.40e-2)" "unprognostic (8.28e-3)" "unprognostic (1.22e-2)" "unprognostic (5.20e-3)" "unprognostic (8.42e-2)" "unprognostic (3.37e-3)" "unprognostic (1.17e-1)" "unprognostic (2.74e-2)" "unprognostic (4.95e-2)" "unprognostic (4.90e-2)" "unprognostic (1.06e-1)" "unprognostic (4.25e-2)" "prognostic unfavorable (1.22e-7)" "unprognostic (5.83e-3)" "unprognostic (1.99e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (9.69e-4)" 197.9 37.9 12.3 82.1 11.7 34.8 134.6 14.7 14.6 106.5 28.6 193.6 31.4 173.5 24.9 217.5 121.2 66.4 166.2 11.8 13.7 66.0 40.8 92.9 31.6 19.2 16.3 81.2 52.7 5.6 33.1 59.7 15.1 84.2 28.8 3.6 69.6 91.3 37.3 78.2 75.8 151.9 14.1 34.0 89.1 28.3 18.4 12.2 52.2 20.2 31.3 129.9 124.2 12.5 211.8 142.3 149.5 76.1 149.0 208.8 108.1 648.5 424.2 492.0 459.1 113.0 65.2 1.3 281.7 440.8 148.6 99.5 84.7 653.6 380.6 1.8 46.1 32.3 159.2 73.6 151.0 2.7 59.5 219.1 146.0 429.4 222.7 148.8 366.1 12.5 159.7 2.5 432.5 216.1 0.8 162.4 79.1 3.3 70.0 1.6 260.0 2.2 99.7 5.8 19.3 27.2 360.3 34.8 113.9 153.7 76.5 203.8 821.6 600.0 510.6 565.7 574.2 11.5 3.8 3.8 458.9 46.9 219.8 2.0 19.4 0.3 0.6 7.6 0.3 42.0 0.1 0.2 25.5 58.7 0.2 0.3 0.4 0.9 7.5 157.3 0.2 13.2 12.3 11.7 14.7 14.6 11.8 13.7 19.2 16.3 15.1 14.1 18.4 12.5 67.0 83.3 7.9 0.7 16.1 69.6 42.7 151.4 16.5 1.2 30.4 44.8 54.3 8.6 37.4 7.3 0.0 53.8 23.6 0.6 1.9 167.6 190.2 6.4 76.9 128.9 0.0 12.2 0.8 104.9 494.3 112.8 1.5 7.1 45.6 7.4 82.5 0.4 69.4 0.0 0.6 0.4 42.7 13.2 85.2 114.9 70.2 36.5 33.8 12.2 65.9 0.2 0.0 0.5 0.4 221.1 0.1 91.4 1.0 51.5 0.1 1.2 18.2 1.6 26.3 89.2 130.5 4.3 6.3 55.7 66.9 22.2 3.6 9.5 0.5 65.2 U2AF1 "RN, RNU2AF1, U2AF35, U2AFBP" ENSG00000160201 "U2 small nuclear RNA auxiliary factor 1" Q01081 21 43092956-43107570 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 492.9;Basal respiratory cells: 406.9;Ionocytes: 266.5;Langerhans cells: 374.7;Suprabasal keratinocytes: 433.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 607.7" "Low region specificity" "Detected in all" "HPA044833, HPA052083" Supported Enhanced Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 36: HEL - Hemostasis" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "HPA044833: AB_10960990, HPA052083: AB_2681720" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (5.98e-2)" "unprognostic (2.87e-2)" "unprognostic (1.36e-1)" "unprognostic (8.06e-2)" "unprognostic (2.76e-2)" "unprognostic (4.29e-4)" "unprognostic (4.81e-4)" "unprognostic (3.42e-2)" "unprognostic (2.31e-3)" "unprognostic (8.85e-2)" "unprognostic (2.14e-6)" "unprognostic (1.08e-1)" "unprognostic (1.40e-2)" "unprognostic (1.72e-1)" "unprognostic (1.26e-2)" 62.9 47.6 36.8 31.1 39.9 85.9 58.7 39.8 46.9 57.6 38.0 79.3 25.8 68.9 27.8 64.3 60.8 18.7 43.0 37.7 41.1 42.8 48.0 57.3 45.2 39.3 40.2 69.3 41.8 32.7 60.1 34.6 38.5 48.0 26.8 28.9 49.1 40.8 74.9 47.5 57.2 35.8 38.3 65.4 58.2 54.4 38.8 61.8 62.6 24.8 55.9 60.7 50.7 40.8 101.1 27.7 250.5 71.3 28.7 38.8 248.1 88.2 82.4 105.4 115.3 486.0 59.8 20.8 35.1 54.3 125.6 33.0 161.1 36.3 104.9 114.6 134.0 607.7 61.2 117.9 77.0 264.0 115.2 45.5 90.6 177.1 100.6 43.5 62.8 238.0 105.8 113.4 97.2 324.4 271.1 358.1 287.6 123.4 108.3 485.1 166.9 211.9 99.8 15.4 125.9 77.6 212.6 98.6 147.6 36.5 125.5 147.5 12.1 79.2 59.6 82.0 236.3 191.4 178.3 48.8 80.3 333.6 118.6 211.9 141.0 153.1 101.2 140.4 106.7 140.2 112.7 95.5 150.4 134.2 112.9 109.1 213.1 93.1 196.9 240.7 149.3 188.7 36.8 39.9 39.8 46.9 37.7 41.1 39.3 40.2 38.5 38.3 38.8 40.8 9.5 19.2 18.1 3.9 37.8 492.9 32.5 406.9 86.6 23.9 5.7 2.8 5.0 17.2 153.5 1.8 43.8 19.5 15.3 16.5 1.9 5.2 3.1 4.2 4.4 51.7 18.2 45.0 5.2 6.0 20.7 51.8 44.4 4.2 28.4 3.8 31.8 16.2 23.2 18.5 4.6 17.0 266.5 33.0 374.7 4.1 18.3 30.6 202.7 4.7 19.3 13.0 27.8 3.0 6.2 4.8 17.0 22.6 60.3 31.1 43.2 3.1 107.6 60.7 6.6 39.1 110.7 16.4 18.9 79.8 433.6 23.8 46.6 1.3 20.2 39.1 UBE2D1 "E2(17)KB1, SFT, UBC4/5, UBCH5, UbcH5A" ENSG00000072401 "Ubiquitin conjugating enzyme E2 D1" P51668 10 58334979-58370751 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 138.7;tongue: 65.3" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 194.4;Suprabasal keratinocytes: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 112.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (1.12e-1)" "unprognostic (2.08e-1)" "unprognostic (4.23e-3)" "unprognostic (1.76e-1)" "unprognostic (1.52e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (5.58e-4)" "unprognostic (2.20e-2)" "unprognostic (1.03e-1)" "unprognostic (2.24e-2)" "unprognostic (4.37e-3)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.04e-6)" "unprognostic (9.71e-3)" "unprognostic (4.14e-1)" "unprognostic (1.95e-1)" "unprognostic (5.66e-2)" 13.0 11.8 5.3 16.7 5.7 32.4 7.8 6.6 8.1 8.9 4.4 11.4 7.0 12.6 7.5 11.6 7.1 9.5 33.3 6.1 6.2 8.1 8.3 8.9 13.8 6.6 6.4 8.4 5.5 8.9 3.9 8.9 6.6 9.5 12.0 5.4 5.5 6.7 138.7 5.9 8.3 13.6 6.4 13.4 6.4 4.5 6.3 7.8 8.4 65.3 11.4 15.1 5.6 6.7 19.1 10.2 18.8 24.4 37.5 30.0 12.1 12.4 21.2 13.9 20.3 20.9 16.4 0.0 19.0 18.6 10.3 17.1 36.6 18.0 19.5 19.8 21.2 4.9 3.7 12.2 24.4 15.3 11.8 34.8 19.9 14.4 26.8 18.7 28.1 13.1 10.0 7.8 19.1 6.1 16.5 17.1 23.0 11.7 15.7 13.8 16.9 10.6 21.2 11.2 14.0 18.8 24.2 40.3 20.6 28.5 14.8 10.2 22.8 5.3 18.6 18.2 13.7 19.7 16.4 16.8 16.7 31.3 6.2 10.1 38.5 17.8 6.2 27.1 7.2 8.9 7.3 7.9 20.0 9.8 7.5 6.2 112.3 8.2 23.4 8.3 9.8 23.4 5.3 5.7 6.6 8.1 6.1 6.2 6.6 6.4 6.6 6.4 6.3 6.7 41.6 12.8 11.2 5.5 54.3 194.4 94.1 60.6 46.1 23.7 45.6 45.5 92.4 17.2 39.0 27.6 18.8 29.9 41.7 27.4 76.3 62.3 5.0 32.6 46.9 42.5 41.7 12.0 18.5 42.0 50.4 51.9 38.7 51.2 22.9 19.6 27.5 15.6 73.7 16.8 17.1 40.1 69.2 90.6 104.0 3.0 33.2 147.7 53.4 4.7 94.6 17.9 22.6 12.5 21.2 81.2 52.7 32.4 26.4 108.4 16.1 54.3 33.6 16.1 6.6 51.4 59.1 33.5 19.9 47.1 190.2 149.0 42.8 14.9 28.5 118.2 UFM1 "bA131P10.1, C13orf20" ENSG00000120686 "Ubiquitin fold modifier 1" P61960 13 38349849-38363619 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039758 Approved NA NA 240000 "Cluster 6: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "HPA039758: AB_10697555" "unprognostic (8.08e-2)" "unprognostic (3.29e-2)" "unprognostic (1.49e-1)" "prognostic favorable (9.35e-4)" "unprognostic (3.33e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (9.67e-2)" "unprognostic (1.68e-1)" "unprognostic (3.92e-2)" "unprognostic (1.45e-1)" "unprognostic (8.11e-2)" "unprognostic (7.03e-2)" "unprognostic (4.90e-3)" "unprognostic (1.12e-2)" "unprognostic (3.99e-1)" "unprognostic (8.23e-2)" "unprognostic (1.90e-1)" 41.9 43.1 35.6 47.8 38.1 100.1 47.4 35.6 44.0 43.5 40.5 39.7 48.5 58.4 64.8 29.9 37.1 42.2 35.8 37.6 42.1 45.3 52.9 41.6 52.3 39.1 37.5 50.3 67.0 32.7 37.2 53.1 39.4 49.9 50.6 32.1 58.5 50.3 24.8 42.8 47.8 39.2 40.1 46.9 52.3 19.8 36.9 31.9 52.1 26.2 48.5 41.7 35.8 44.5 31.3 18.1 47.4 46.2 81.8 97.4 43.3 94.1 72.8 47.7 50.3 56.2 63.1 50.9 29.1 81.8 94.5 51.6 44.9 57.4 67.6 71.4 27.5 42.5 33.9 50.0 107.8 63.3 59.1 81.6 84.3 46.4 127.6 69.9 47.7 39.6 28.5 68.5 68.6 35.6 42.8 52.5 48.9 94.4 45.8 48.9 84.8 50.6 60.2 40.6 17.9 40.6 32.4 54.8 80.8 64.9 40.0 49.1 56.5 55.1 33.5 88.1 53.1 64.7 43.9 67.6 116.6 32.2 84.5 71.5 30.6 41.1 30.7 42.0 37.3 40.1 31.2 28.7 26.7 37.6 30.4 31.8 15.5 39.6 40.3 45.0 32.4 34.7 35.6 38.1 35.6 44.0 37.6 42.1 39.1 37.5 39.4 40.1 36.9 44.5 92.1 80.1 73.3 20.9 141.6 136.9 151.7 147.8 108.1 24.0 102.7 64.4 66.3 64.3 115.3 62.5 20.9 87.2 112.7 84.8 99.7 91.5 38.6 126.8 113.4 78.8 31.7 52.6 29.0 102.3 140.2 121.5 92.8 148.1 115.3 53.4 68.9 119.6 97.6 6.7 34.9 113.5 107.8 94.3 148.3 13.3 59.0 102.0 94.3 43.1 92.3 26.7 62.8 26.2 58.9 161.9 102.2 40.3 330.9 215.8 95.2 136.5 141.2 22.3 19.7 87.3 88.1 56.6 44.9 110.2 173.3 140.4 93.0 45.2 80.8 220.3 USHBP1 "AIEBP, FLJ38709, MCC2" ENSG00000130307 "USH1 protein network component harmonin binding protein 1" Q8N6Y0 19 17249171-17282786 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 41.5;Endothelial cells: 28.3;Hepatic stellate cells: 21.4;Ionocytes: 20.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 10.9;HeLa: 5.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA052471 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA052471: AB_2681843" "unprognostic (1.48e-1)" "unprognostic (1.82e-1)" "unprognostic (2.91e-2)" "unprognostic (3.97e-2)" "unprognostic (1.73e-2)" "unprognostic (2.66e-3)" "unprognostic (1.44e-3)" "unprognostic (3.94e-2)" "unprognostic (4.42e-3)" "unprognostic (2.52e-1)" "unprognostic (4.46e-3)" "unprognostic (5.12e-1)" "unprognostic (5.12e-2)" "unprognostic (1.16e-1)" "unprognostic (6.88e-2)" "unprognostic (8.45e-2)" "unprognostic (1.88e-1)" 8.8 1.9 5.0 1.6 4.9 2.9 8.2 7.2 5.2 2.9 4.1 1.9 1.9 3.6 1.1 1.3 3.1 1.7 12.6 5.0 4.1 4.5 1.2 6.9 2.6 4.6 4.5 1.4 4.8 0.8 1.2 5.6 5.1 2.3 0.5 1.1 2.0 0.9 6.2 2.1 2.2 1.3 3.3 3.5 1.7 1.0 5.1 0.5 4.5 4.8 0.5 2.8 2.3 4.6 0.6 0.9 1.7 0.4 0.0 0.0 10.9 0.3 0.0 0.0 0.0 1.9 0.9 2.9 3.4 0.0 0.1 1.2 0.1 0.2 0.0 0.7 1.3 0.7 5.0 1.1 0.0 2.4 2.4 0.3 0.0 0.2 0.2 0.6 3.2 1.1 1.4 1.5 0.0 0.1 0.4 2.4 1.3 0.3 2.7 1.4 0.2 0.7 0.0 1.3 1.1 0.7 0.7 0.7 0.2 0.9 1.3 0.9 1.9 1.8 0.5 1.5 1.0 2.6 0.9 2.8 0.6 1.5 0.6 2.0 0.4 0.7 0.7 0.3 0.6 0.6 0.6 0.7 0.1 1.0 0.9 0.8 1.6 0.7 0.2 0.8 0.8 0.5 5.0 4.9 7.2 5.2 5.0 4.1 4.6 4.5 5.1 3.3 5.1 4.6 41.5 3.2 0.5 0.7 0.0 0.5 0.9 0.1 0.6 0.3 0.5 0.1 6.7 0.0 0.7 0.0 0.0 1.1 3.1 0.2 0.0 0.1 0.7 0.7 0.8 28.3 0.0 0.0 0.4 0.6 0.9 0.9 0.0 1.5 1.3 0.1 21.4 0.3 0.1 0.0 0.5 0.2 20.3 0.6 1.2 0.2 0.6 0.3 5.4 6.5 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.2 1.3 0.1 1.7 0.0 2.2 1.5 0.2 0.4 0.2 1.0 4.5 0.7 0.3 0.0 0.8 USP13 IsoT-3 ENSG00000058056 "Ubiquitin specific peptidase 13" Q92995 3 179653032-179804366 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 149.2;tongue: 108.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 208.5;Inhibitory neurons: 52.2;Theca cells: 58.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 15.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HDLM-2: 93.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004827 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Cytosol" "HPA004827: AB_1080497" "unprognostic (1.00e-2)" "unprognostic (2.09e-1)" "unprognostic (5.82e-2)" "unprognostic (7.14e-2)" "unprognostic (9.94e-2)" "unprognostic (3.96e-2)" "prognostic unfavorable (2.40e-5)" "unprognostic (1.76e-1)" "unprognostic (4.55e-2)" "unprognostic (7.79e-2)" "unprognostic (1.69e-3)" "unprognostic (2.22e-2)" "prognostic unfavorable (3.46e-6)" "unprognostic (4.93e-2)" "unprognostic (9.79e-2)" "unprognostic (3.38e-2)" "prognostic unfavorable (3.06e-4)" 6.2 11.9 3.9 2.8 13.6 1.5 5.3 8.6 12.0 3.3 0.0 2.9 1.2 5.7 3.4 4.0 3.4 4.5 42.5 3.7 4.7 3.0 4.6 5.4 3.6 11.3 10.5 12.5 4.1 4.0 5.8 2.6 12.7 4.3 2.2 7.1 6.2 2.7 149.2 2.2 1.9 6.3 6.4 2.1 1.7 6.0 8.1 2.4 9.7 108.9 3.5 3.5 2.2 34.4 27.6 11.3 20.0 14.8 8.9 14.1 11.6 18.6 17.4 23.7 18.8 17.1 9.6 35.6 18.0 17.2 27.6 2.6 21.4 9.1 26.4 93.3 14.8 9.0 23.6 14.4 6.3 26.5 1.1 10.5 3.0 18.8 18.5 9.1 16.6 11.9 4.7 43.0 15.7 15.0 22.5 3.0 17.9 1.3 13.1 29.3 20.2 27.4 11.7 7.9 13.0 14.5 14.1 16.9 7.2 5.4 37.0 12.7 24.1 28.6 27.6 23.7 64.1 29.5 21.2 78.3 13.0 15.0 27.2 0.1 0.3 0.0 2.6 0.5 15.6 3.2 1.8 3.8 1.5 0.9 1.2 1.3 0.0 0.0 0.7 4.5 0.7 1.3 3.9 13.6 8.6 12.0 3.7 4.7 11.3 10.5 12.7 6.4 8.1 34.4 45.0 9.6 35.9 14.0 5.3 2.5 1.9 1.4 0.6 13.7 7.1 5.2 208.5 5.7 5.4 1.8 6.2 10.7 5.6 1.4 15.6 1.1 2.6 13.9 11.4 10.1 9.6 5.5 23.2 4.4 2.4 12.0 4.1 2.5 2.5 35.5 22.1 7.6 4.3 16.8 52.2 2.9 0.0 4.8 3.5 3.6 9.3 5.0 14.2 16.9 1.7 7.0 3.1 36.2 42.5 1.0 12.2 9.4 4.5 4.4 0.1 2.7 3.7 10.2 13.1 17.8 12.0 6.1 2.8 4.8 1.6 5.1 4.1 58.8 4.5 1.4 VAMP5 ENSG00000168899 "Vesicle associated membrane protein 5" O95183 2 85584431-85593406 "Predicted membrane proteins" "Differentiation, Myogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 487.9;Endothelial cells: 337.8;Hepatic stellate cells: 486.2;Kupffer cells: 340.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 364.7;LHCN-M2: 428.9;TIME: 250.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035082 Supported Approved "Nucleoplasm,Plasma membrane" NA NA 130000 "Cluster 7: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA035082: AB_10610564" "unprognostic (1.92e-1)" "unprognostic (3.09e-2)" "unprognostic (6.09e-2)" "unprognostic (1.13e-2)" "unprognostic (4.16e-2)" "unprognostic (1.25e-3)" "unprognostic (1.28e-2)" "unprognostic (5.29e-2)" "unprognostic (1.17e-2)" "unprognostic (3.49e-2)" "unprognostic (2.22e-1)" "unprognostic (7.59e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (9.61e-3)" "unprognostic (3.46e-2)" "unprognostic (1.71e-2)" "unprognostic (2.60e-1)" 134.0 117.4 71.0 59.9 74.1 41.2 118.4 72.9 89.1 78.6 66.8 76.4 23.3 79.4 33.2 45.3 84.3 58.0 114.7 69.4 76.1 90.0 79.3 134.6 92.7 79.1 71.4 52.8 29.0 14.7 31.9 74.1 74.2 72.8 20.5 2.9 36.9 36.7 217.3 44.5 54.1 77.2 73.8 97.5 54.0 11.4 78.0 50.9 63.8 199.6 41.2 87.1 69.7 71.7 0.8 0.2 2.4 0.0 89.3 155.8 2.4 98.5 155.9 95.5 104.5 39.5 15.1 0.3 2.3 172.2 50.7 1.1 0.0 2.4 42.2 142.9 2.8 1.9 2.5 56.1 187.2 4.5 0.9 108.4 9.6 40.1 1.1 138.9 364.7 61.7 0.4 0.3 428.9 14.5 63.1 13.8 0.1 27.2 0.6 92.4 0.4 2.7 2.7 3.6 0.2 3.4 0.6 27.4 0.5 2.2 3.2 5.1 250.0 2.3 6.7 7.5 0.2 0.1 3.1 2.4 110.5 5.4 65.9 59.1 222.6 176.5 180.5 503.8 171.7 60.7 136.1 135.2 79.0 54.5 102.4 125.1 70.2 94.4 424.9 86.4 248.7 283.0 71.0 74.1 72.9 89.1 69.4 76.1 79.1 71.4 74.2 73.8 78.0 71.7 487.9 19.2 21.2 3.6 43.9 60.8 39.8 104.1 39.3 0.8 14.9 27.3 84.4 71.4 70.1 44.1 0.0 22.9 64.5 38.8 29.4 29.9 1.8 7.7 64.7 337.8 12.6 35.6 0.1 49.1 7.2 148.0 9.7 7.9 44.4 22.2 486.2 198.6 80.3 3.3 0.2 20.5 36.7 340.8 91.5 10.2 192.6 147.8 275.7 4.7 136.0 17.5 112.3 0.5 1.6 44.2 51.9 165.1 68.4 64.7 126.5 91.2 50.6 1.0 59.2 152.2 83.9 5.5 6.6 19.8 45.3 21.6 88.5 19.2 7.8 49.4 VWA1 "FLJ22215, VWA-1, WARP" ENSG00000179403 "Von Willebrand factor A domain containing 1" Q6PCB0 1 1434861-1442882 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 275.1;Endothelial cells: 142.7;Syncytiotrophoblasts: 290.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 47.2;CACO-2: 46.7;CAPAN-2: 136.6;Hep G2: 84.4;SCLC-21H: 47.6;T-47d: 61.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 250000 "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (2.78e-1)" "unprognostic (4.85e-2)" "unprognostic (5.91e-3)" "unprognostic (2.75e-1)" "unprognostic (2.67e-3)" "unprognostic (6.73e-2)" "unprognostic (9.52e-3)" "unprognostic (8.11e-2)" "unprognostic (1.18e-1)" "unprognostic (1.61e-1)" "unprognostic (3.47e-1)" "unprognostic (2.79e-2)" "unprognostic (3.13e-2)" "unprognostic (1.15e-1)" "unprognostic (1.69e-2)" "unprognostic (3.08e-2)" "unprognostic (6.71e-2)" 36.2 15.2 55.3 31.5 91.7 0.2 38.4 79.4 76.7 51.0 24.4 114.3 15.3 70.4 11.5 41.3 50.4 22.4 38.0 59.4 58.9 58.6 133.3 29.6 13.7 103.4 81.6 22.5 55.3 12.5 20.0 38.4 87.9 131.3 5.3 2.3 64.0 203.6 10.1 26.2 37.6 20.4 74.2 11.7 52.6 27.1 88.3 3.0 67.4 3.4 5.1 118.5 50.6 151.2 47.2 15.4 2.2 15.7 0.4 1.4 24.5 3.1 0.1 2.2 0.1 46.7 136.6 0.0 43.0 1.3 5.0 12.1 15.9 8.1 0.3 3.0 11.3 1.5 0.1 84.4 3.5 0.0 5.5 2.7 0.4 1.0 0.0 0.4 0.6 0.0 1.6 0.0 0.1 11.7 0.1 0.9 6.1 16.5 4.3 0.6 0.8 2.2 2.7 7.9 47.6 7.4 0.0 41.7 5.8 3.7 61.1 0.6 1.4 0.1 0.6 0.4 15.2 0.3 0.2 0.2 2.3 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.3 91.7 79.4 76.7 59.4 58.9 103.4 81.6 87.9 74.2 88.3 151.2 103.4 19.2 36.1 5.9 2.8 6.5 19.1 5.2 12.0 7.6 40.4 59.4 3.6 44.3 14.2 53.3 4.2 275.1 1.4 24.2 7.9 82.0 0.6 16.0 46.2 142.7 12.5 2.7 0.5 65.0 99.2 28.3 16.8 17.7 1.3 2.0 8.2 49.4 22.8 15.2 1.5 8.9 6.1 1.0 4.3 4.0 34.2 1.1 24.9 18.7 2.6 52.1 0.0 13.0 48.7 48.0 11.0 59.0 2.6 21.5 0.8 5.4 10.7 4.3 6.6 62.4 17.2 0.8 2.1 11.9 8.5 290.3 1.3 6.3 10.4 14.9 WARS1 "IFI53, IFP53, WARS" ENSG00000140105 "Tryptophanyl-tRNA synthetase 1" P23381 14 100333790-100376805 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 324.4" "Cell type enhanced" "Detected in some" "Adipocytes: 66.4;Cytotrophoblasts: 16.5;Endothelial cells: 38.5;Hofbauer cells: 43.1;Syncytiotrophoblasts: 16.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 1345.3;non-classical monocyte: 1608.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 908.5;SK-MEL-30: 1012.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005573, HPA018944" Enhanced Enhanced Cytosol No No 49000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" Cytosol "HPA005573: AB_2667366, HPA018944: AB_2669986" "unprognostic (5.36e-2)" "unprognostic (5.98e-2)" "unprognostic (3.99e-2)" "unprognostic (1.54e-1)" "unprognostic (2.30e-1)" "unprognostic (9.25e-2)" "prognostic unfavorable (7.88e-4)" "unprognostic (5.14e-2)" "unprognostic (4.26e-2)" "prognostic favorable (1.94e-4)" "unprognostic (4.84e-2)" "unprognostic (3.21e-1)" "unprognostic (3.53e-3)" "unprognostic (1.37e-1)" "unprognostic (9.45e-2)" "unprognostic (1.62e-1)" "unprognostic (5.92e-3)" 100.7 67.9 40.3 185.6 44.4 70.5 65.4 40.1 45.5 35.9 45.2 67.8 44.8 39.6 70.3 54.4 50.8 48.7 157.6 44.2 56.0 83.6 47.9 207.5 139.0 72.0 52.6 21.2 47.5 39.2 63.4 324.4 65.3 49.1 72.0 37.8 49.5 38.3 74.7 28.4 67.7 76.2 47.6 110.6 70.1 67.7 55.0 61.7 159.9 67.0 86.2 107.7 30.7 44.9 91.2 85.7 54.6 319.1 78.7 110.7 87.3 117.4 220.7 232.1 301.4 57.4 80.2 101.7 105.5 277.4 59.7 151.1 158.8 130.3 153.1 154.4 48.3 64.1 60.9 72.3 908.5 184.9 101.6 126.9 186.9 141.3 290.1 74.5 225.0 66.1 202.8 255.0 107.5 178.0 64.3 87.1 55.4 94.1 152.2 51.4 86.5 64.9 119.3 80.8 145.7 84.9 69.4 58.7 1012.4 70.5 153.6 234.7 153.1 25.7 58.9 269.2 61.3 446.4 277.1 191.9 295.0 144.2 205.5 96.5 471.7 610.4 41.5 1345.3 38.4 71.4 34.5 38.4 337.9 68.0 24.8 28.6 170.9 44.5 1608.2 54.7 44.8 672.7 40.3 44.4 40.1 45.5 44.2 56.0 72.0 52.6 65.3 47.6 55.0 44.9 66.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 16.5 3.7 0.0 0.0 0.0 0.0 0.0 0.0 38.5 0.0 0.0 0.0 0.0 11.5 5.5 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 16.6 0.5 0.0 0.0 0.0 WWTR1 "DKFZp586I1419, TAZ" ENSG00000018408 "WW domain containing transcription regulator 1" Q9GZV5 3 149517235-149736714 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 229.3;Endothelial cells: 221.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 212.1;RPTEC TERT1: 151.1;SK-MEL-30: 160.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007415, CAB017483, CAB068248" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" Cytosol "CAB017483: AB_2216639, CAB068248: AB_2665648, HPA007415: AB_1080602" "unprognostic (1.85e-2)" "unprognostic (2.24e-2)" "unprognostic (3.41e-3)" "unprognostic (1.33e-2)" "unprognostic (7.94e-2)" "unprognostic (1.37e-1)" "unprognostic (2.41e-2)" "unprognostic (2.22e-1)" "unprognostic (1.74e-2)" "unprognostic (2.34e-1)" "unprognostic (1.63e-2)" "unprognostic (3.32e-1)" "unprognostic (1.17e-3)" "unprognostic (2.76e-2)" "unprognostic (2.53e-1)" "unprognostic (3.98e-2)" "unprognostic (1.01e-3)" 41.6 13.8 19.2 22.4 20.8 0.2 37.2 18.9 19.6 41.8 32.6 74.9 8.0 42.1 13.4 35.8 33.7 39.6 36.4 20.7 53.9 45.9 19.0 41.2 7.2 52.6 39.9 43.9 31.8 14.1 13.6 44.0 35.9 34.5 13.5 4.2 27.6 32.1 13.2 24.8 21.6 43.7 37.1 19.5 32.7 7.2 23.0 4.7 31.6 15.0 6.1 59.2 34.3 41.0 58.9 80.5 40.6 48.7 48.6 86.8 43.0 32.6 57.5 17.7 17.8 46.7 53.2 0.1 212.1 45.0 53.3 36.1 28.4 28.5 17.9 22.0 19.3 0.0 18.6 37.8 27.3 0.0 0.1 45.3 7.4 61.8 26.6 65.4 136.3 0.0 0.0 0.2 61.7 9.2 0.2 0.2 8.2 0.2 96.6 0.0 50.6 0.4 151.1 9.4 0.0 0.4 21.1 17.2 160.2 31.5 26.5 1.6 94.2 29.0 16.2 24.8 67.4 0.6 0.5 0.8 66.8 0.1 78.8 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.5 0.1 19.2 20.8 18.9 19.6 20.7 53.9 52.6 39.9 35.9 37.1 23.0 41.0 125.7 64.1 89.7 60.4 1.1 51.7 229.3 34.6 60.9 2.2 58.1 56.8 46.8 141.5 87.8 49.7 4.2 12.2 2.0 0.5 7.9 72.0 21.9 136.3 89.1 221.2 0.0 3.2 8.7 27.1 82.3 77.9 10.2 144.4 7.6 45.0 111.4 21.9 4.1 0.0 6.1 1.2 10.2 6.0 32.3 7.9 57.8 4.6 30.2 94.6 2.1 11.0 0.0 7.5 12.7 45.8 0.0 126.4 2.9 86.7 1.2 59.8 53.9 2.0 59.2 76.1 58.0 2.2 0.8 46.3 35.5 14.8 6.5 48.4 2.4 93.5 YES1 "c-yes, HsT441, Yes" ENSG00000176105 "YES proto-oncogene 1, Src family tyrosine kinase" P07947 18 721588-812546 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 20.2" "Lineage enriched" "Detected in many" 9 "granulocytes: 20.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004370, HPA026480" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "CAB004370: AB_627370, HPA026480: AB_1858921" "unprognostic (3.28e-1)" "unprognostic (1.62e-2)" "unprognostic (5.87e-2)" "unprognostic (2.47e-2)" "unprognostic (6.24e-2)" "unprognostic (4.24e-2)" "unprognostic (6.01e-2)" "unprognostic (1.03e-2)" "unprognostic (1.95e-2)" "unprognostic (1.85e-3)" "prognostic unfavorable (2.46e-4)" "unprognostic (2.14e-1)" "unprognostic (8.12e-2)" "unprognostic (4.65e-2)" "unprognostic (1.81e-1)" "unprognostic (4.79e-2)" "unprognostic (4.11e-1)" 25.2 13.5 11.9 10.5 12.7 4.1 21.8 12.7 14.3 17.4 11.5 21.8 24.8 16.0 17.9 22.7 13.9 18.9 13.1 11.7 13.7 27.9 50.6 17.2 6.2 13.9 13.2 12.4 26.5 20.0 6.1 41.7 13.5 15.0 22.7 8.3 21.0 11.9 8.3 16.7 23.7 15.9 14.2 27.4 21.3 19.0 14.3 10.5 22.0 14.6 8.8 20.3 11.5 14.1 42.7 20.8 64.3 50.6 37.8 46.5 75.6 27.9 56.2 32.0 43.7 49.9 30.7 0.1 28.8 47.3 41.0 24.3 60.8 49.1 62.3 0.2 20.7 12.6 19.4 35.1 30.6 9.9 21.7 35.7 51.7 48.5 53.6 39.8 109.8 7.0 56.1 18.4 46.1 29.3 6.0 13.0 40.9 26.0 26.4 7.4 50.6 3.6 46.8 49.6 13.1 15.3 57.5 42.9 37.1 42.3 29.7 20.5 95.6 78.4 86.2 59.9 75.8 15.7 8.3 2.6 29.7 13.8 47.6 20.2 0.0 1.0 2.2 0.0 1.5 0.1 0.4 1.2 0.0 0.0 1.0 1.7 0.0 1.1 0.0 0.0 0.1 0.6 11.9 12.7 12.7 14.3 11.7 13.7 13.9 13.2 13.5 14.2 14.3 14.1 120.3 25.6 36.8 18.9 3.3 60.2 46.8 21.4 50.1 6.0 38.1 26.7 18.2 24.3 31.3 29.5 6.2 37.1 52.9 40.3 3.9 29.6 29.4 32.8 35.0 91.0 22.8 12.0 0.4 39.2 26.6 35.4 57.6 43.6 13.9 35.9 39.7 44.9 4.9 3.3 10.3 37.2 14.2 5.4 14.7 11.7 18.3 5.0 24.9 46.9 2.0 16.8 16.5 31.7 30.2 51.0 28.8 12.8 28.9 65.4 33.1 45.6 29.0 8.6 19.7 35.9 23.8 20.3 13.6 53.1 49.7 45.6 27.5 42.4 36.7 66.6 ZEB1 "AREB6, BZP, FECD6, NIL-2-A, PPCD3, TCF8, ZEB, Zfhep, Zfhx1a" ENSG00000148516 "Zinc finger E-box binding homeobox 1" P37275 10 31318495-31529814 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 287.8;Excitatory neurons: 276.1;Inhibitory neurons: 261.9;Microglial cells: 479.7;Oligodendrocyte precursor cells: 968.6" "Cancer enhanced" "Detected in all" "glioma: 15.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 113.1;TIME: 87.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027524, CAB058686, CAB079943" Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm Nucleoli "CAB058686: AB_2665569, CAB079943: , HPA027524: AB_1844977" "unprognostic (1.54e-1)" "unprognostic (3.08e-1)" "unprognostic (3.42e-2)" "unprognostic (1.04e-1)" "unprognostic (4.85e-2)" "unprognostic (7.40e-2)" "unprognostic (1.34e-2)" "unprognostic (5.59e-2)" "unprognostic (1.30e-1)" "unprognostic (2.96e-2)" "unprognostic (3.48e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (7.34e-6)" "unprognostic (5.59e-3)" "unprognostic (1.19e-1)" "unprognostic (1.62e-2)" "unprognostic (1.66e-2)" 26.6 8.6 16.4 12.9 16.2 8.6 16.8 14.0 20.1 33.2 9.9 49.2 6.0 38.7 13.4 11.7 18.6 20.0 34.8 15.2 22.8 7.5 10.4 16.0 9.6 21.1 19.2 9.3 3.8 3.4 7.9 17.5 21.2 14.5 12.3 14.8 8.0 26.9 54.4 7.0 11.8 39.9 16.8 8.1 18.1 10.1 18.2 29.9 11.2 60.5 9.7 24.4 16.4 18.5 0.1 11.1 35.1 43.9 58.4 113.1 0.0 32.7 44.9 6.6 9.3 0.2 0.1 11.3 15.6 39.6 9.3 0.0 14.9 0.0 11.8 19.1 7.9 0.0 7.0 6.3 44.4 9.8 0.3 53.4 0.1 19.6 17.6 21.4 54.9 9.5 7.5 14.4 42.7 0.1 33.7 6.2 2.3 0.0 6.6 11.6 66.0 5.1 12.9 0.0 0.9 15.6 11.1 0.0 0.0 7.2 0.0 6.7 87.7 40.8 9.4 10.0 16.7 9.1 6.3 12.8 10.9 0.0 4.2 4.9 0.0 5.4 2.4 0.0 3.2 4.1 3.2 1.7 1.3 3.1 6.8 3.5 8.5 6.6 0.0 3.1 5.0 1.6 16.4 16.2 14.0 20.1 15.2 22.8 21.1 19.2 21.2 16.8 18.2 18.5 104.4 0.0 7.7 212.9 34.6 11.2 3.0 2.0 0.6 42.7 1.4 2.8 106.3 1.5 3.6 1.8 45.9 0.3 22.0 0.0 0.0 2.1 110.1 7.2 287.8 110.6 0.0 12.2 276.1 2.7 0.5 66.1 2.0 6.5 1.3 17.0 49.6 13.4 1.2 10.1 261.9 0.0 0.0 3.8 25.6 141.8 30.7 6.3 26.6 479.7 10.7 7.2 7.2 968.6 7.3 2.5 0.0 102.0 33.2 3.7 0.0 1.6 1.5 43.4 78.9 99.2 74.2 17.4 15.7 1.1 8.7 0.7 36.2 12.0 0.0 3.8 ZFAND2A AIRAP ENSG00000178381 "Zinc finger AN1-type containing 2A" Q8N6M9 7 1152071-1160759 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 490.1;Paneth cells: 310.4;Prostatic glandular cells: 255.2;Urothelial cells: 322.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 179.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019469 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 22: Epithelial cell types - Mixed function" "HPA019469: AB_1859009" "unprognostic (1.03e-1)" "unprognostic (1.61e-1)" "unprognostic (6.85e-2)" "unprognostic (1.63e-2)" "unprognostic (3.08e-2)" "unprognostic (1.03e-2)" "unprognostic (7.12e-2)" "unprognostic (1.10e-2)" "unprognostic (2.10e-3)" "unprognostic (7.52e-2)" "unprognostic (8.78e-2)" "unprognostic (6.48e-2)" "prognostic unfavorable (5.47e-7)" "unprognostic (5.44e-3)" "unprognostic (7.60e-2)" "unprognostic (6.46e-2)" "unprognostic (2.59e-2)" 27.0 26.0 57.7 10.6 58.9 80.5 24.1 62.8 98.9 18.1 52.7 26.4 17.8 20.7 14.7 21.5 18.8 18.1 18.5 63.0 61.3 30.8 81.1 32.5 15.4 58.7 60.4 20.9 33.8 16.4 22.4 21.1 60.8 23.2 18.1 15.1 19.6 12.1 13.2 20.3 19.9 14.4 60.3 24.3 32.5 26.9 59.3 13.4 27.0 7.9 11.8 25.2 21.7 66.2 44.7 50.6 12.8 29.3 28.6 20.3 20.3 40.1 32.6 40.1 30.6 35.7 35.4 14.5 15.8 33.5 63.3 59.8 10.2 10.6 40.5 11.9 21.1 9.8 22.7 179.8 54.4 29.2 19.3 19.1 34.2 32.9 58.3 28.2 14.0 32.8 56.0 33.0 29.6 69.6 8.3 32.8 51.8 105.8 69.3 25.3 2.4 23.0 16.5 19.0 18.6 19.0 14.3 39.1 50.5 26.7 40.1 58.5 18.2 29.6 23.2 34.3 54.7 40.0 51.2 27.3 29.1 32.5 64.3 71.6 25.8 34.2 31.3 24.7 28.8 32.3 28.1 33.0 18.7 34.5 26.9 23.4 31.8 33.2 25.3 34.6 39.5 30.0 57.7 58.9 62.8 98.9 63.0 61.3 58.7 60.4 60.8 60.3 59.3 66.2 65.4 32.1 17.2 4.2 40.6 22.6 490.1 27.6 46.7 15.6 39.8 34.7 17.9 22.8 17.4 7.3 16.7 18.9 49.1 211.8 23.5 21.6 9.7 46.3 33.4 40.7 126.9 17.2 5.6 39.5 46.6 50.8 54.0 83.8 116.4 9.7 20.3 50.3 40.6 11.8 5.8 207.9 18.3 29.2 119.6 12.6 13.4 121.1 32.0 1.0 31.6 23.7 21.6 2.5 7.4 65.7 310.4 18.0 89.7 255.2 29.3 34.1 13.1 25.6 0.0 16.6 40.5 47.1 39.0 64.8 27.7 65.9 156.4 13.3 123.6 322.2 ZNF222 ENSG00000159885 "Zinc finger protein 222" Q9UK12 19 44025342-44033110 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "Early spermatids: 78.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA004086 Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 21: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "Nuclear bodies" "HPA004086: AB_2273259" "unprognostic (1.91e-3)" "unprognostic (3.41e-2)" "unprognostic (8.08e-2)" "unprognostic (1.02e-1)" "unprognostic (3.81e-2)" "unprognostic (7.45e-2)" "unprognostic (1.75e-3)" "unprognostic (6.75e-2)" "unprognostic (1.58e-2)" "unprognostic (7.58e-2)" "prognostic favorable (5.56e-7)" "unprognostic (2.19e-3)" "unprognostic (1.36e-1)" "unprognostic (2.44e-1)" "unprognostic (8.42e-2)" "unprognostic (2.05e-2)" "unprognostic (1.16e-3)" 2.8 4.1 3.7 3.0 3.7 5.3 4.5 6.0 5.3 3.2 3.6 2.5 1.6 2.8 3.9 1.9 2.9 3.4 4.3 3.6 4.5 3.8 2.8 3.2 4.4 4.3 4.5 4.7 3.1 3.7 5.1 3.1 4.4 3.5 2.7 6.8 2.6 3.3 2.3 2.6 2.7 3.2 3.4 4.6 3.1 9.1 4.2 5.8 4.1 2.3 4.3 3.8 2.0 4.9 3.8 4.5 7.4 6.7 5.5 5.5 0.3 4.1 7.3 4.7 7.4 2.1 2.4 1.2 6.1 4.4 5.5 1.3 5.2 3.6 5.9 4.9 4.7 6.4 6.5 3.8 7.0 0.2 5.2 4.2 5.4 3.9 6.5 7.4 4.5 5.2 1.2 2.4 5.9 0.5 4.3 2.4 4.5 1.8 1.7 0.1 7.7 2.1 3.8 12.1 4.0 9.0 6.4 1.2 5.4 6.3 1.6 6.2 3.3 5.1 4.9 2.9 5.0 10.6 9.1 0.1 2.7 0.1 5.8 7.7 2.4 5.0 5.9 1.6 4.8 4.7 5.4 5.7 2.5 5.9 6.2 4.6 4.8 4.9 2.0 2.9 4.2 2.8 3.7 3.7 6.0 5.3 3.6 4.5 4.3 4.5 4.4 3.4 4.2 4.9 2.1 0.0 1.5 1.0 1.9 2.5 1.9 2.3 0.0 5.3 2.1 2.0 1.9 0.0 1.8 5.5 0.0 1.8 3.1 0.8 7.9 2.4 78.5 1.6 1.7 2.4 3.0 4.8 3.7 1.2 1.1 3.0 1.5 2.7 4.5 3.5 3.3 1.1 2.3 6.7 4.2 2.1 6.1 1.3 1.5 6.9 1.8 1.5 1.8 1.0 1.7 6.3 3.1 3.5 3.6 0.8 0.4 2.2 1.5 0.8 1.1 1.3 0.3 2.8 0.0 2.8 3.0 9.9 3.5 0.7 1.7 1.1 3.7 3.5 1.2 1.1 ZNF292 "bA393I2.3, KIAA0530, ZFP292, Zn-15, Zn-16" ENSG00000188994 "Zinc finger protein 292" O60281 6 87152833-87265943 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032154, HPA050618" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nuclear membrane" "HPA032154: AB_10601930, HPA050618: AB_2681190" "unprognostic (6.26e-2)" "unprognostic (1.32e-2)" "unprognostic (2.97e-1)" "unprognostic (3.66e-2)" "unprognostic (1.02e-2)" "unprognostic (2.07e-2)" "unprognostic (2.08e-3)" "unprognostic (2.28e-2)" "unprognostic (2.81e-2)" "unprognostic (4.03e-2)" "unprognostic (8.43e-2)" "unprognostic (7.46e-2)" "unprognostic (9.06e-2)" "unprognostic (2.80e-1)" "unprognostic (1.22e-1)" "unprognostic (2.02e-1)" "unprognostic (7.36e-2)" 6.8 6.3 4.4 7.8 4.6 25.4 9.6 17.8 8.7 8.7 1.8 7.3 7.9 10.3 9.5 6.6 6.2 6.7 6.2 3.9 3.1 6.3 6.4 5.7 10.9 3.2 2.5 13.7 6.9 13.8 8.5 8.8 3.8 8.2 6.8 26.4 8.3 7.2 5.5 8.6 8.8 6.4 2.2 8.0 8.1 6.2 3.7 14.3 9.6 5.6 9.1 7.1 7.3 10.3 8.3 4.7 16.1 14.2 9.0 8.1 16.8 6.4 8.1 7.4 10.1 8.2 5.7 12.8 9.0 8.4 10.4 8.4 10.1 9.6 15.9 29.3 7.6 17.3 6.4 6.8 6.7 14.0 7.6 8.1 9.2 7.3 9.4 11.8 6.9 13.6 12.8 19.1 8.1 4.6 8.1 12.0 8.1 2.9 4.4 16.9 15.9 4.9 6.2 17.8 11.9 16.8 8.0 5.3 6.1 9.2 5.4 16.0 7.8 9.8 6.8 7.2 10.1 17.5 12.3 8.6 10.8 11.8 7.2 60.3 16.9 20.0 15.7 5.4 14.8 46.6 16.8 17.3 8.0 42.8 18.7 16.1 83.6 11.2 5.7 25.0 18.3 8.3 4.4 4.6 17.8 8.7 3.9 3.1 3.2 2.5 3.8 2.2 3.7 10.3 64.2 60.9 72.4 147.2 99.0 66.2 31.2 46.1 70.0 167.7 48.0 47.9 76.8 48.6 51.8 25.8 123.0 27.0 89.9 64.9 9.8 122.3 44.4 119.3 89.6 55.6 47.3 43.5 176.6 38.5 36.6 52.3 66.3 203.1 29.1 135.6 40.0 19.0 26.8 186.7 225.7 52.7 40.7 29.2 53.1 12.4 60.0 46.3 32.0 124.6 53.0 62.5 65.9 210.6 209.8 52.2 49.5 66.2 90.8 49.4 72.5 14.5 50.1 99.4 32.9 84.6 59.5 56.3 34.1 36.7 51.4 211.8 90.8 66.8 44.5 58.5 ZNF419 "ZAPHIR, ZNF419A" ENSG00000105136 "Zinc finger protein 419" Q96HQ0 19 57487711-57496098 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 31.9" "HPA003152, HPA003274" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Nucleoli fibrillar center" "HPA003152: AB_1080716, HPA003274: AB_1080714" "unprognostic (3.50e-2)" "unprognostic (1.40e-5)" "unprognostic (1.12e-1)" "unprognostic (2.63e-2)" "unprognostic (2.55e-2)" "unprognostic (8.26e-2)" "unprognostic (2.93e-2)" "unprognostic (1.21e-2)" "unprognostic (3.18e-1)" "unprognostic (1.33e-1)" "unprognostic (8.55e-5)" "prognostic unfavorable (6.47e-4)" "unprognostic (1.20e-1)" "unprognostic (2.42e-1)" "unprognostic (1.55e-1)" "unprognostic (1.28e-1)" "prognostic favorable (2.53e-5)" 6.0 8.7 10.0 4.6 10.1 3.0 6.2 10.7 12.6 4.8 9.9 6.3 3.8 5.3 9.7 4.7 6.2 3.5 8.2 10.0 10.1 8.1 6.6 7.0 7.4 9.4 8.9 7.8 4.6 9.1 13.4 6.1 8.8 8.9 3.6 11.1 6.4 6.3 10.4 7.4 6.2 4.0 8.9 10.6 5.3 5.3 10.2 8.0 10.8 7.8 8.9 5.4 4.6 10.1 5.4 6.0 10.3 10.5 4.7 7.1 8.9 6.4 8.8 5.8 31.9 3.8 3.4 1.8 5.1 4.5 5.2 1.6 4.9 13.3 8.0 0.5 22.4 8.3 9.1 4.2 16.8 6.5 6.0 9.7 19.3 5.8 13.8 12.0 6.4 8.0 0.9 1.3 7.3 0.9 10.9 6.7 6.8 0.7 7.9 10.1 9.9 7.6 6.3 11.5 8.4 9.4 6.5 6.0 6.2 8.8 5.3 9.7 6.6 7.0 7.7 2.5 5.6 15.2 18.0 4.5 5.6 3.5 5.7 4.5 2.7 6.1 5.2 3.3 8.9 14.3 8.9 6.6 4.7 15.8 13.8 7.4 3.2 9.7 2.7 3.4 6.5 4.4 10.0 10.1 10.7 12.6 10.0 10.1 9.4 8.9 8.8 8.9 10.2 10.1 3.1 0.0 5.3 3.6 7.2 4.1 5.7 4.9 2.8 8.1 4.3 5.2 5.3 4.3 5.2 7.3 6.2 5.0 4.2 1.3 0.0 5.8 0.3 2.0 2.1 4.8 1.2 2.5 3.3 1.8 2.4 3.7 0.5 1.7 4.5 7.4 5.7 4.6 3.2 10.1 2.8 1.8 8.2 3.2 1.7 0.5 1.8 1.8 5.4 0.0 4.1 6.8 7.2 3.5 1.9 2.5 2.8 5.7 1.6 9.0 2.0 1.9 1.8 9.5 6.6 2.9 3.3 4.9 10.4 2.1 3.8 8.3 4.8 4.2 1.8 5.6 ZNF432 KIAA0798 ENSG00000256087 "Zinc finger protein 432" O94892 19 52031378-52095738 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Horizontal cells: 26.9;Rod photoreceptor cells: 30.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA052082, HPA060274, HPA065606" Uncertain Enhanced Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 15: RT4 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA052082: AB_2681719, HPA060274: AB_2684238, HPA065606: AB_2685518" "unprognostic (1.62e-1)" "unprognostic (2.34e-1)" "unprognostic (1.92e-1)" "unprognostic (7.04e-3)" "unprognostic (1.08e-2)" "unprognostic (2.41e-3)" "unprognostic (3.19e-2)" "unprognostic (2.56e-1)" "unprognostic (6.92e-2)" "unprognostic (1.83e-1)" "unprognostic (3.14e-2)" "unprognostic (5.49e-3)" "prognostic unfavorable (6.47e-4)" "unprognostic (1.90e-1)" "unprognostic (2.04e-1)" "unprognostic (1.90e-1)" "prognostic favorable (4.11e-5)" 6.3 13.4 3.2 3.7 3.9 8.0 6.5 5.7 3.7 6.5 8.8 5.5 5.2 7.0 8.7 6.6 6.0 3.5 6.0 3.4 5.5 5.1 4.1 5.6 4.3 3.9 3.7 6.8 18.0 5.6 12.4 4.4 3.9 11.8 4.3 24.6 7.1 4.5 4.1 7.8 5.2 4.3 2.9 4.4 6.4 7.2 4.3 4.0 6.7 4.4 4.1 5.0 6.5 4.8 4.6 3.7 8.2 13.0 5.6 7.2 2.8 5.2 3.9 3.7 5.9 3.2 2.7 3.1 1.6 5.6 4.0 3.4 4.8 4.5 6.4 3.2 11.8 9.5 9.2 6.0 2.6 0.0 8.5 7.3 3.6 5.4 7.9 7.1 4.9 3.7 2.6 14.0 6.8 2.6 9.3 5.2 3.0 2.4 6.3 4.9 9.5 5.4 5.5 22.2 4.8 5.0 8.1 4.4 2.6 5.8 3.9 3.7 7.0 3.1 4.7 3.7 5.5 7.2 10.7 7.5 7.2 0.8 6.1 0.9 1.1 1.3 1.4 1.3 1.0 1.9 0.8 0.8 0.9 1.2 1.5 1.1 1.0 0.6 0.6 0.6 1.2 0.8 3.2 3.9 5.7 3.7 3.4 5.5 3.9 3.7 3.9 2.9 4.3 4.8 6.2 16.0 10.0 8.1 8.0 2.0 3.3 3.4 3.4 9.8 3.8 3.2 6.0 2.8 11.6 9.2 16.7 2.7 6.4 3.7 3.9 3.5 14.7 11.9 6.4 5.7 10.2 2.5 9.4 1.6 5.8 5.8 6.6 9.0 12.6 7.8 3.9 1.3 2.3 26.9 6.7 4.9 4.1 4.1 1.3 12.4 3.7 3.2 3.6 9.4 3.8 7.7 10.3 9.0 6.9 2.1 5.2 4.5 4.0 3.6 2.0 2.7 11.6 30.7 6.6 7.1 6.4 10.0 8.4 2.2 2.3 4.9 6.5 4.2 3.1 3.3 ZNF578 FLJ31384 ENSG00000258405 "Zinc finger protein 578" Q96N58 19 52453553-52516882 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 6.3" "Cell type enhanced" "Detected in many" "Horizontal cells: 6.7;NK-cells: 8.2;Oligodendrocyte precursor cells: 10.1;Rod photoreceptor cells: 8.2" "Cancer enriched" "Detected in single" 5 "testis cancer: 1.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SuSa: 5.5;U-266/84: 9.4" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" "unprognostic (6.57e-3)" "unprognostic (1.43e-2)" "unprognostic (1.56e-2)" "unprognostic (3.77e-2)" "unprognostic (1.60e-3)" "unprognostic (2.96e-3)" "unprognostic (5.42e-2)" "unprognostic (5.69e-2)" "unprognostic (2.55e-2)" "unprognostic (8.14e-2)" "unprognostic (9.57e-3)" "unprognostic (7.61e-2)" "unprognostic (1.81e-1)" "unprognostic (2.64e-1)" "unprognostic (1.82e-1)" "unprognostic (3.96e-2)" "unprognostic (2.42e-1)" 0.7 0.6 2.1 0.7 3.1 0.8 0.8 5.1 2.7 0.9 1.4 0.5 0.4 1.1 1.8 0.4 1.3 0.6 1.2 2.0 3.0 0.9 0.3 0.7 0.7 2.5 2.2 1.7 0.7 1.0 0.3 1.3 2.4 1.4 0.7 3.1 0.7 1.2 0.9 1.2 0.4 0.9 1.6 1.2 0.6 6.3 2.6 1.0 1.7 0.6 0.7 0.5 0.2 3.2 0.5 0.3 2.1 2.7 1.2 0.7 1.2 1.3 0.7 0.5 0.9 0.9 0.7 0.9 0.5 2.0 2.5 0.7 1.1 0.6 0.6 0.2 1.5 0.8 1.6 0.5 1.1 0.2 2.7 1.9 0.3 0.9 0.8 1.0 0.9 0.8 0.6 0.6 2.6 0.8 0.9 1.2 4.1 0.6 0.7 0.8 0.8 0.3 1.8 2.7 0.6 1.5 0.6 0.6 0.2 5.5 2.0 0.6 1.3 0.6 0.7 0.8 0.7 0.5 9.4 0.8 0.1 0.2 1.7 1.4 0.3 0.4 0.9 0.3 0.7 0.5 0.6 0.5 0.1 0.8 0.7 0.8 0.5 1.1 0.3 0.5 0.3 0.3 2.1 3.1 5.1 2.7 2.0 3.0 2.5 2.2 2.4 1.6 2.6 3.2 3.9 0.0 0.0 4.9 1.3 0.9 1.7 0.2 0.0 4.4 0.5 0.5 4.1 0.0 0.2 0.0 4.2 0.7 4.0 0.0 0.0 0.2 5.9 0.9 1.4 1.6 0.0 0.8 3.9 0.2 0.8 1.4 0.0 2.1 1.3 3.9 0.7 0.0 0.2 6.7 5.8 0.1 0.0 0.3 0.6 6.1 0.6 0.4 0.0 0.0 0.4 1.8 8.2 10.1 6.2 0.0 0.0 0.0 0.4 1.0 0.2 0.8 0.1 8.2 0.0 0.7 1.8 0.2 2.3 0.1 0.4 0.8 1.8 2.6 0.1 1.7 ZNF597 "FLJ33071, HIT-4" ENSG00000167981 "Zinc finger protein 597" Q96LX8 16 3432414-3443504 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 8.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001556 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nucleoli" "HPA001556: AB_1080740" "unprognostic (1.98e-1)" "unprognostic (8.07e-2)" "unprognostic (1.03e-1)" "unprognostic (9.15e-3)" "unprognostic (2.88e-1)" "unprognostic (6.16e-2)" "unprognostic (1.84e-2)" "unprognostic (5.56e-2)" "unprognostic (3.70e-2)" "unprognostic (2.84e-2)" "unprognostic (1.34e-1)" "unprognostic (8.75e-3)" "unprognostic (4.73e-2)" "unprognostic (7.26e-2)" "unprognostic (4.58e-1)" "unprognostic (2.89e-1)" "unprognostic (5.99e-3)" 1.6 1.9 1.1 1.5 1.1 1.9 1.7 1.0 1.3 1.4 0.8 1.1 1.2 1.5 2.1 1.1 1.4 1.9 1.3 1.0 1.5 1.3 1.7 2.4 2.1 0.9 1.1 2.0 1.6 1.4 1.3 2.3 1.0 1.4 1.0 2.3 1.1 1.2 0.7 1.3 1.3 1.2 1.0 1.8 1.2 3.9 1.4 1.5 2.0 1.1 1.8 1.6 0.9 1.2 0.0 1.2 1.5 3.7 1.1 1.7 5.9 1.8 2.2 1.7 2.1 0.0 2.3 3.1 1.7 2.0 1.3 1.0 3.5 1.6 2.2 1.9 1.4 5.3 3.6 2.2 1.6 3.2 3.1 2.2 2.5 1.9 2.1 1.7 4.7 1.6 1.1 2.0 2.0 1.0 2.3 3.3 5.0 1.4 0.0 1.4 4.5 2.1 1.4 4.9 2.0 2.8 3.5 1.8 1.4 4.1 1.5 4.7 3.1 2.8 1.4 0.0 1.7 2.6 2.9 0.4 0.0 1.8 1.7 3.1 0.8 8.8 0.9 1.7 1.5 0.9 0.7 0.8 0.8 0.7 1.2 0.9 0.2 0.7 0.8 0.4 1.2 0.6 1.1 1.1 1.0 1.3 1.0 1.5 0.9 1.1 1.0 1.0 1.4 1.2 8.3 25.6 2.6 0.0 4.3 0.1 1.8 0.3 2.8 2.1 4.3 3.8 1.9 1.5 5.2 1.8 0.0 1.2 3.6 1.4 0.0 1.1 8.1 3.8 2.1 4.2 2.4 0.4 2.9 1.0 1.8 2.6 1.5 4.5 3.8 3.0 2.5 1.4 1.2 0.0 1.9 2.1 0.0 1.0 0.7 4.1 1.2 2.7 0.0 4.7 3.0 1.8 0.0 1.0 2.0 1.8 1.0 2.2 2.1 2.4 0.7 1.3 0.9 3.1 6.6 2.7 2.6 5.3 8.0 1.9 0.4 1.5 3.3 1.1 2.4 2.3 ZNF792 FLJ38451 ENSG00000180884 "Zinc finger protein 792" Q3KQV3 19 34956354-34964229 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 7.0;Endothelial cells: 7.5;Hepatic stellate cells: 6.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 12.8;HMC-1: 16.1;HUVEC TERT2: 11.0;OE19: 9.7;SH-SY5Y: 10.2" "Low region specificity" "Detected in many" "HPA035157, HPA035158" Supported Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" "HPA035157: AB_2674497, HPA035158: AB_10603010" "unprognostic (1.31e-1)" "unprognostic (7.31e-2)" "prognostic favorable (2.72e-4)" "unprognostic (1.24e-1)" "unprognostic (2.15e-1)" "unprognostic (7.91e-2)" "unprognostic (2.41e-5)" "unprognostic (2.49e-2)" "unprognostic (4.30e-2)" "unprognostic (1.22e-1)" "unprognostic (1.49e-1)" "unprognostic (4.62e-1)" "unprognostic (6.88e-3)" "unprognostic (3.88e-1)" "unprognostic (2.48e-1)" "unprognostic (6.02e-2)" "unprognostic (2.77e-3)" 3.8 1.3 1.1 2.2 1.6 1.3 3.6 3.6 1.3 2.4 1.1 1.9 2.1 2.2 1.9 1.0 2.6 1.7 2.0 0.9 1.2 1.6 1.3 4.1 3.8 1.2 1.4 2.3 1.8 2.8 1.1 3.4 1.2 1.8 2.3 2.5 2.2 2.2 1.2 1.5 2.4 2.6 0.9 3.6 2.5 0.9 1.3 4.0 1.9 2.1 2.8 2.3 1.4 0.9 1.1 3.8 1.8 2.7 1.8 1.4 0.0 1.1 2.0 1.3 1.6 1.5 1.8 1.6 3.4 1.5 0.6 0.7 2.6 2.0 2.0 4.6 0.6 12.8 1.1 2.9 1.3 1.1 16.1 1.6 0.6 1.1 0.5 2.3 11.0 1.1 3.4 0.0 2.2 0.9 4.5 1.1 1.3 9.7 0.8 2.9 0.0 0.2 1.0 3.5 0.9 10.2 1.0 1.0 1.3 1.6 1.2 3.4 4.5 1.9 2.4 0.8 1.2 0.3 1.0 0.9 2.1 0.2 0.9 5.4 0.5 4.1 1.9 0.4 2.3 1.3 3.0 2.7 0.7 0.9 3.3 2.8 0.1 3.0 0.3 0.1 3.2 1.7 1.1 1.6 3.6 1.3 0.9 1.2 1.2 1.4 1.2 0.9 1.3 0.9 7.0 0.0 1.1 0.7 2.1 0.5 0.1 0.6 0.6 0.8 1.2 0.9 2.0 0.0 0.2 0.0 2.1 0.1 2.9 0.7 0.0 1.8 0.2 0.7 0.7 7.5 1.8 3.4 0.3 2.6 0.4 1.0 2.0 0.8 1.3 1.4 6.4 0.6 1.5 0.0 0.6 1.7 0.0 3.5 1.4 0.4 1.5 1.6 0.0 1.0 1.6 0.5 2.1 2.5 0.3 2.7 1.0 0.0 1.6 0.2 0.5 0.5 0.2 1.8 0.0 0.9 0.6 0.0 1.5 0.4 0.4 0.1 3.0 0.7 1.4 0.1 ZNF799 "HIT-40, MGC71805, ZNF842" ENSG00000196466 "Zinc finger protein 799" Q96GE5 19 12390016-12401271 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA003150, HPA018683" Approved Approved "Nucleoplasm,Centriolar satellite" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "Centriolar satellite" "HPA003150: AB_1080725, HPA018683: AB_2669920" "unprognostic (2.96e-1)" "unprognostic (1.10e-1)" "unprognostic (8.84e-2)" "prognostic favorable (2.39e-4)" "unprognostic (3.63e-2)" "unprognostic (5.18e-3)" "unprognostic (3.02e-1)" "unprognostic (8.83e-3)" "unprognostic (4.47e-5)" "unprognostic (1.45e-1)" "unprognostic (5.56e-3)" "unprognostic (6.55e-2)" "unprognostic (1.41e-1)" "unprognostic (2.75e-1)" "unprognostic (2.04e-1)" "unprognostic (8.91e-3)" "unprognostic (1.23e-3)" 2.9 3.0 2.4 1.5 2.5 1.6 3.8 3.5 2.6 3.4 2.3 2.5 2.1 2.9 2.0 1.8 3.9 2.1 2.0 2.5 2.3 3.4 3.8 2.9 2.6 2.7 2.4 4.4 2.2 2.4 1.1 4.7 2.5 2.6 2.6 1.6 2.2 2.2 1.8 2.4 2.5 2.4 2.4 2.9 2.0 2.7 2.8 3.1 2.0 2.3 2.3 2.7 2.6 2.9 3.0 2.4 3.0 7.2 1.6 1.5 6.0 1.6 2.2 3.9 3.7 4.6 1.2 3.8 2.8 1.9 1.9 2.1 2.4 2.8 3.7 0.0 2.2 3.0 2.0 7.5 0.5 2.3 5.3 1.8 1.7 2.8 2.2 1.2 1.9 3.6 3.1 0.0 2.5 4.2 4.8 3.3 1.6 3.9 6.1 0.5 4.5 3.9 4.0 7.2 1.9 2.2 2.9 0.7 0.9 2.2 3.2 4.2 1.8 4.0 2.3 4.8 1.8 2.6 4.4 3.0 0.4 2.4 1.7 3.1 2.6 2.9 3.9 2.6 4.5 4.7 3.6 5.7 2.1 4.4 3.4 2.7 2.5 2.8 1.6 2.7 4.5 2.3 2.4 2.5 3.5 2.6 2.5 2.3 2.7 2.4 2.5 2.4 2.8 2.9 7.5 6.4 1.5 5.2 3.8 2.4 3.1 1.4 4.6 1.8 5.6 4.3 5.4 1.5 2.0 3.7 0.0 15.2 3.0 3.2 5.9 4.6 8.6 8.0 2.4 7.3 4.2 0.8 5.4 1.3 2.9 2.9 2.6 8.5 3.8 2.9 3.3 1.4 4.4 0.0 4.0 5.7 6.1 1.2 2.6 2.3 2.5 2.2 0.0 10.3 2.1 1.3 6.2 8.0 4.7 2.5 2.3 1.2 2.0 2.1 3.6 2.9 4.7 3.1 13.1 2.8 4.6 4.5 5.6 4.0 1.4 4.5 3.7 1.9 4.0 2.6