Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ACTA2 ACTSA ENSG00000107796 "Actin alpha 2, smooth muscle" P62736 10 88935074-88991339 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 6678.8;seminal vesicle: 5920.3;smooth muscle: 8099.9" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 1007.7;Peritubular cells: 5290.7;Sertoli cells: 3030.6;Smooth muscle cells: 2394.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 58.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 390.6;fHDF/TERT166: 641.1;HHSteC: 625.8;HSkMC: 345.1;hTERT-RPE1: 743.4;SuSa: 296.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 101.0" "CAB000002, CAB003761, CAB013531, HPA041264, HPA041271" Enhanced Supported "Actin filaments" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Actin filaments" "CAB000002: AB_2223500, CAB003761: AB_562031, CAB013531: , HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (7.05e-2)" "unprognostic (2.54e-1)" "unprognostic (2.30e-3)" "unprognostic (3.18e-2)" "unprognostic (3.33e-2)" "unprognostic (6.19e-2)" "unprognostic (2.36e-2)" "unprognostic (1.71e-2)" "unprognostic (4.25e-2)" "unprognostic (1.20e-1)" "unprognostic (1.44e-1)" "unprognostic (6.93e-2)" "prognostic unfavorable (1.37e-8)" "unprognostic (1.87e-3)" "unprognostic (2.30e-1)" "unprognostic (7.91e-2)" "unprognostic (2.09e-3)" 1035.2 241.6 54.0 728.1 61.4 3.9 838.4 52.7 121.1 2000.3 61.4 2755.1 248.9 6678.8 1360.1 1509.9 3104.3 906.1 1069.2 53.4 54.6 312.2 161.8 732.8 173.7 59.0 55.9 798.0 91.4 80.6 60.8 771.3 55.3 2642.8 866.4 8.2 414.7 5920.3 202.1 355.7 701.6 8099.9 54.1 452.1 1427.1 263.9 56.1 56.5 312.0 214.0 48.4 3002.5 1367.0 52.9 3.9 19.0 49.3 102.7 198.1 390.6 9.5 109.8 136.8 11.9 45.4 0.0 8.8 7.2 11.5 641.1 8.6 1.4 1.8 25.4 11.3 60.6 11.3 0.4 5.6 119.3 625.8 0.8 3.2 345.1 44.9 73.9 28.5 743.4 11.3 3.0 0.0 7.1 128.8 10.8 1.0 28.3 2.5 0.2 1.2 1.4 0.2 4.6 27.1 5.0 0.7 7.6 10.2 7.9 1.0 296.8 32.4 1.0 27.9 24.0 4.0 30.2 9.3 21.1 1.6 0.6 29.6 10.2 26.1 28.1 12.3 17.5 17.6 8.7 13.8 6.0 14.1 19.8 10.8 1.8 1.5 10.7 11.1 4.0 14.2 0.4 58.7 10.7 54.0 61.4 52.7 121.1 53.4 54.6 59.0 55.9 55.3 54.1 56.1 52.9 65.4 9.6 6.1 5.5 4.4 43.2 23.4 16.5 22.8 1.1 22.7 1007.7 25.1 2.8 5.2 0.0 6.2 16.3 7.3 1.9 1.9 1.8 11.1 11.1 225.4 41.1 0.0 4.0 3.6 0.9 16.8 316.3 10.7 8.2 5.7 448.9 474.0 4.6 37.7 0.0 1.1 2.7 4.1 5.4 67.6 48.8 141.4 12.6 55.2 61.8 4.2 13.4 4.1 1.0 0.3 2.0 3.0 5290.7 3.7 17.5 3.4 9.5 10.9 1.4 3030.6 72.0 2394.6 4.0 13.8 11.1 40.5 23.7 16.5 36.0 5.7 10.4 ADAM33 "C20orf153, dJ964F7.1, DKFZp434K0521" ENSG00000149451 "ADAM metallopeptidase domain 33" Q9BZ11 20 3667965-3682246 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 280.4" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 40.8;Fibroblasts: 45.2;Leydig cells: 22.7;Microglial cells: 18.7;Smooth muscle cells: 17.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 82.4;ASC TERT1: 104.9;BJ: 38.5;BJ hTERT+: 64.7;fHDF/TERT166: 38.9;U-2197: 50.9" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Low region specificity" "Detected in all" "HPA067152, HPA071758" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear speckles" "HPA067152: AB_2685791, HPA071758: " "unprognostic (1.10e-1)" "unprognostic (3.02e-2)" "unprognostic (2.24e-2)" "unprognostic (3.35e-3)" "unprognostic (4.39e-3)" "unprognostic (7.43e-4)" "unprognostic (7.14e-3)" "unprognostic (1.67e-1)" "unprognostic (1.78e-3)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (3.56e-1)" "unprognostic (2.75e-11)" "unprognostic (1.05e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-5)" "unprognostic (3.10e-3)" 53.3 3.8 7.8 10.5 8.5 0.1 47.4 5.8 12.3 280.4 8.4 157.2 11.0 151.8 19.0 31.6 106.9 32.8 26.7 6.7 9.3 3.9 2.0 18.0 6.2 16.0 8.0 58.7 6.0 0.5 6.9 12.7 16.4 87.0 12.1 1.0 19.6 57.5 9.1 22.0 43.4 53.0 5.9 8.3 44.8 22.5 6.9 0.9 18.4 14.1 2.2 125.4 159.0 6.2 0.0 0.0 0.2 0.0 82.4 104.9 0.2 38.5 64.7 11.2 21.3 0.1 0.0 0.0 0.2 38.9 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.1 0.0 13.0 0.0 0.0 18.2 0.0 4.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 2.8 0.2 2.9 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.1 0.1 0.0 0.2 0.0 50.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.8 8.5 5.8 12.3 6.7 9.3 16.0 8.0 16.4 5.9 6.9 6.2 3.9 0.0 0.0 7.2 0.1 5.5 0.1 0.0 0.6 0.0 0.3 0.3 3.3 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.5 1.8 40.8 2.4 0.0 0.0 1.3 0.0 0.1 45.2 2.6 1.2 0.0 3.1 1.8 0.0 0.5 0.0 11.4 0.0 0.0 0.3 8.8 0.8 22.7 0.8 3.6 18.7 0.0 2.2 0.0 8.0 0.1 0.0 0.0 10.1 0.0 0.2 0.0 0.9 0.0 0.1 6.6 6.8 17.1 0.7 0.5 0.3 3.1 0.5 0.7 0.0 0.0 0.1 ADAMTS12 ENSG00000151388 "ADAM metallopeptidase with thrombospondin type 1 motif 12" P58397 5 33523535-33892019 "Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 25.2;Fibroblasts: 22.9;Leydig cells: 22.1;Microglial cells: 73.1;Sertoli cells: 52.6;Theca cells: 55.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 47.4;hTERT-RPE1: 88.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA035973, HPA075079" Uncertain Approved Nucleoli,Mitochondria "Secreted to extracellular matrix" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 52: Non-specific - Transcription" Nucleoli Mitochondria "HPA035973: AB_10669663, HPA075079: AB_2732278" "unprognostic (6.18e-3)" "unprognostic (3.12e-4)" "unprognostic (1.05e-1)" "unprognostic (8.37e-2)" "unprognostic (1.65e-1)" "unprognostic (3.52e-1)" "unprognostic (2.60e-2)" "unprognostic (3.49e-3)" "unprognostic (3.78e-3)" "unprognostic (3.39e-2)" "unprognostic (5.63e-3)" "unprognostic (1.45e-1)" "unprognostic (4.27e-7)" "unprognostic (4.45e-3)" "unprognostic (1.47e-1)" "unprognostic (5.85e-2)" "prognostic unfavorable (6.78e-4)" 9.0 5.2 0.9 1.6 0.7 0.0 7.8 0.5 0.4 2.7 1.7 2.5 0.5 3.8 0.5 0.9 3.2 4.0 1.6 0.2 0.4 1.3 1.4 5.6 0.9 1.2 0.9 2.7 0.6 0.5 0.6 3.9 1.0 1.3 1.0 0.7 0.9 1.4 0.8 1.5 1.1 6.5 1.5 0.5 1.2 2.0 1.3 0.3 1.9 0.7 0.6 2.2 2.0 3.3 28.7 0.9 25.5 0.0 35.9 17.2 0.0 13.3 33.1 16.8 19.5 0.0 0.0 0.0 0.0 9.0 29.1 0.8 0.7 16.7 24.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 13.8 0.0 47.4 12.2 88.0 0.0 0.0 0.0 0.1 26.6 0.0 0.0 0.0 5.0 0.0 0.0 0.0 29.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 36.9 0.0 0.0 0.0 28.0 36.2 0.3 7.9 4.4 3.5 0.0 23.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.5 0.4 0.2 0.4 1.2 0.9 1.0 1.5 1.3 3.3 6.4 0.0 0.0 1.3 0.5 0.8 0.0 0.0 0.0 0.1 1.5 2.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 4.9 1.2 25.2 2.1 0.0 0.0 3.0 0.2 0.4 22.9 0.0 0.6 0.0 3.3 11.4 0.2 0.6 0.0 6.2 0.0 0.0 0.3 2.1 3.0 22.1 0.2 7.2 73.1 0.0 5.3 0.0 0.5 7.8 0.1 0.0 17.7 0.0 0.1 0.0 2.4 0.7 0.2 52.6 1.7 19.1 0.4 4.7 0.1 0.9 0.8 0.3 55.4 0.0 0.1 ADAMTS13 "C9orf8, DKFZp434C2322, FLJ42993, MGC118899, MGC118900, TTP, vWF-CP, VWFCP" ENSG00000160323 "ADAM metallopeptidase with thrombospondin type 1 motif 13" Q76LX8 9 133414358-133459402 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 63.8" "Cell type enhanced" "Detected in many" "Astrocytes: 16.0;Early spermatids: 19.3;Excitatory neurons: 12.4;Inhibitory neurons: 12.4;Late spermatids: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042014, HPA042844, HPA052077" Approved Approved Vesicles "Secreted to blood" NA NA 1300000000 120000000 "Cluster 34: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA042014: AB_2677798, HPA042844: AB_2678200, HPA052077: " "unprognostic (1.09e-1)" "unprognostic (1.45e-1)" "unprognostic (8.75e-4)" "unprognostic (1.49e-2)" "unprognostic (1.83e-1)" "unprognostic (3.02e-1)" "unprognostic (4.76e-2)" "unprognostic (2.54e-1)" "unprognostic (2.33e-2)" "unprognostic (1.88e-1)" "unprognostic (4.52e-5)" "unprognostic (1.11e-1)" "unprognostic (9.91e-2)" "unprognostic (4.78e-2)" "unprognostic (3.57e-1)" "unprognostic (1.82e-2)" "unprognostic (2.30e-3)" 2.5 2.8 6.9 0.5 7.3 0.6 2.8 7.6 10.0 5.0 5.3 4.3 3.2 4.2 2.9 2.4 5.7 1.2 6.0 7.1 6.2 9.6 63.8 2.8 0.9 7.0 6.7 6.7 6.2 1.5 12.5 0.8 7.1 6.4 0.9 1.1 2.5 1.4 4.3 2.6 4.4 0.6 6.3 2.6 9.8 13.5 7.2 0.8 6.1 1.4 0.5 4.4 3.1 7.1 0.0 0.8 1.9 2.6 1.5 1.3 0.8 0.7 0.5 0.2 0.3 0.3 2.1 0.2 0.9 0.4 0.6 0.3 0.1 0.4 0.1 1.2 1.7 0.2 0.9 0.4 1.1 0.0 0.7 3.6 0.9 0.2 0.7 1.2 0.1 1.3 0.0 0.8 0.3 3.3 0.0 0.9 2.0 1.1 1.1 0.2 0.2 0.9 0.8 0.8 1.3 4.0 1.4 0.6 1.2 3.9 3.7 0.4 0.5 1.5 0.8 0.9 0.0 1.7 0.3 0.3 1.1 0.2 1.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 7.3 7.6 10.0 7.1 6.2 7.0 6.7 7.1 6.3 7.2 7.1 0.9 0.0 2.0 16.0 1.2 0.3 0.3 0.9 0.0 1.7 1.4 1.9 4.2 4.3 2.4 0.0 0.0 0.2 0.2 1.0 1.9 0.6 19.3 3.6 1.6 0.9 1.2 0.0 12.4 0.4 0.3 1.5 4.6 3.3 0.0 3.0 5.0 1.6 0.2 3.3 12.4 1.3 0.0 0.6 0.0 13.6 0.9 0.3 0.0 7.5 0.0 1.7 0.0 2.0 5.5 0.3 3.0 1.5 0.4 0.4 1.5 0.9 0.7 1.8 0.0 0.4 0.7 6.0 3.9 0.3 0.4 0.1 0.5 1.7 0.9 0.3 ADAMTSL2 KIAA0605 ENSG00000197859 "ADAMTS like 2" Q86TH1 9 133532164-133575519 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 73.2;liver: 35.8" "Cell type enhanced" "Detected in some" "Distal tubular cells: 5.9;Endothelial cells: 5.7;Fibroblasts: 8.5;Microglial cells: 12.2;Sertoli cells: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 7.4;RPMI-8226: 10.1;SH-SY5Y: 30.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045634, HPA053812" Approved Approved Vesicles "Secreted in other tissues" NA NA 170000000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA045634: AB_2679399, HPA053812: AB_2682271" "unprognostic (5.10e-2)" "unprognostic (1.50e-2)" "prognostic unfavorable (5.01e-4)" "unprognostic (8.35e-2)" "unprognostic (1.07e-1)" "unprognostic (5.50e-2)" "unprognostic (6.78e-3)" "unprognostic (1.31e-2)" "unprognostic (5.49e-2)" "unprognostic (1.35e-1)" "prognostic favorable (6.70e-4)" "unprognostic (5.17e-2)" "unprognostic (7.37e-2)" "unprognostic (1.56e-1)" "unprognostic (3.40e-1)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" 3.7 28.5 6.8 1.0 7.3 0.1 1.5 12.0 10.1 2.3 1.4 2.7 1.4 3.1 3.1 1.8 3.1 2.5 73.2 5.8 7.9 25.9 35.8 23.2 3.4 19.3 11.1 4.9 7.1 1.2 15.9 1.5 20.8 8.4 0.3 0.3 3.4 2.2 4.3 0.8 3.2 0.9 8.5 6.4 2.3 3.1 9.3 0.6 12.1 0.5 0.6 5.3 1.6 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.6 0.5 0.0 1.1 0.7 10.1 0.0 0.0 1.4 30.1 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 7.3 12.0 10.1 5.8 7.9 19.3 11.1 20.8 8.5 9.3 7.6 1.4 0.0 0.5 4.9 0.1 0.1 0.1 0.0 0.0 4.2 0.0 0.1 2.3 0.0 0.0 1.8 0.0 0.1 0.0 1.4 5.9 0.2 0.1 0.1 0.1 5.7 5.3 0.0 5.0 0.0 0.1 8.5 0.0 0.0 0.0 0.1 4.6 0.9 0.3 0.0 3.8 0.4 0.0 0.3 0.8 1.1 4.7 0.6 0.0 12.2 0.0 0.4 0.0 2.5 4.0 0.2 0.5 3.0 0.0 0.2 0.0 0.7 0.0 0.2 6.6 1.1 1.6 0.1 0.8 0.4 0.3 0.0 0.6 0.7 1.1 0.2 ADGRA2 "DKFZp434C211, DKFZp434J0911, FLJ14390, GPR124, KIAA1531, TEM5" ENSG00000020181 "Adhesion G protein-coupled receptor A2" Q96PE1 8 37784191-37844896 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Wnt signaling pathway" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 30.6;Endometrial stromal cells: 49.4;Fibroblasts: 36.4;Hepatic stellate cells: 31.4;Leydig cells: 56.5;Microglial cells: 24.4;Muller glia cells: 25.0;Peritubular cells: 41.8;Sertoli cells: 46.0;Smooth muscle cells: 36.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 83.6;ASC TERT1: 64.8;BJ hTERT+: 75.2;fHDF/TERT166: 77.6;HSkMC: 39.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012393 Uncertain NA NA 270000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA012393: AB_1849256" "unprognostic (1.63e-1)" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (1.21e-1)" "unprognostic (2.00e-1)" "unprognostic (6.34e-2)" "unprognostic (1.38e-1)" "unprognostic (3.75e-2)" "unprognostic (1.15e-2)" "unprognostic (1.20e-2)" "unprognostic (3.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.18e-7)" "unprognostic (2.65e-2)" "unprognostic (4.90e-2)" "unprognostic (6.12e-2)" "unprognostic (4.60e-3)" 29.1 4.8 10.0 12.2 8.6 2.0 26.4 8.7 10.1 59.8 5.9 24.1 7.7 45.1 18.2 24.8 43.8 26.2 17.6 9.8 6.5 9.6 4.3 16.2 7.7 7.7 8.3 35.9 5.5 2.2 10.0 48.7 7.8 44.4 8.2 6.7 9.0 54.9 6.6 13.1 12.8 27.8 7.0 11.9 12.3 3.5 11.2 5.2 11.3 8.3 5.6 39.6 32.0 6.6 0.2 2.3 0.3 4.7 83.6 64.8 0.6 38.5 75.2 4.6 12.4 0.5 0.2 0.0 6.9 77.6 3.1 0.9 3.5 0.2 1.5 1.6 1.8 0.2 2.2 0.2 38.1 0.0 0.0 39.4 0.4 3.4 0.8 3.3 22.3 3.0 0.2 0.7 1.2 1.2 0.1 8.0 3.5 0.0 0.6 6.5 4.2 0.4 0.0 0.1 0.3 18.1 1.0 0.2 5.7 17.7 0.2 16.9 18.2 7.6 9.6 11.2 3.5 6.2 0.5 0.1 1.0 20.3 8.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 8.6 8.7 10.1 9.8 6.5 7.7 8.3 7.8 7.0 11.2 6.6 30.6 0.0 0.0 1.0 0.2 0.0 0.1 0.0 0.0 1.0 1.0 1.1 1.3 0.0 0.0 0.0 0.0 1.1 0.2 0.0 1.9 0.1 0.2 1.5 49.4 17.8 0.0 0.0 7.8 1.6 0.6 36.4 0.0 2.2 0.0 0.1 31.4 0.1 2.1 0.0 7.8 0.2 0.0 1.6 0.0 3.1 56.5 1.5 0.0 24.4 1.0 25.0 1.0 3.0 0.8 0.3 0.1 41.8 0.1 0.3 0.0 0.0 0.0 0.7 46.0 5.5 36.0 0.3 0.8 0.5 0.0 2.3 0.4 2.6 0.3 0.2 ADGRL3 "KIAA0768, LEC3, LPHN3" ENSG00000150471 "Adhesion G protein-coupled receptor L3" Q9HAR2 4 61201258-62078335 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.3" "Group enriched" "Detected in many" 11 "Astrocytes: 584.1;Excitatory neurons: 696.1;Inhibitory neurons: 737.4;Oligodendrocyte precursor cells: 1300.8;Oligodendrocytes: 592.1" "Cancer enriched" "Detected in some" 9 "glioma: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 41.8;EFO-21: 10.8;HEK 293: 6.5;SuSa: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015027, HPA015762, CAB022698" Uncertain NA NA "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "CAB022698: , HPA015027: AB_1853243, HPA015762: AB_1853245" "unprognostic (2.88e-2)" "unprognostic (1.12e-1)" "unprognostic (6.43e-4)" "unprognostic (1.79e-2)" "unprognostic (1.88e-1)" "unprognostic (7.56e-2)" "unprognostic (8.70e-2)" "unprognostic (5.42e-2)" "unprognostic (1.62e-2)" "unprognostic (1.28e-1)" "unprognostic (6.81e-2)" "unprognostic (1.28e-1)" "unprognostic (1.62e-5)" "unprognostic (1.03e-2)" "unprognostic (1.44e-1)" "unprognostic (9.85e-3)" "unprognostic (4.23e-3)" 7.1 6.2 25.1 1.1 25.7 0.0 2.5 14.0 30.7 5.5 0.0 4.0 2.5 3.9 1.8 1.0 2.4 1.6 2.6 30.4 25.0 1.6 0.4 2.6 0.4 15.3 24.6 1.1 0.3 6.7 0.9 1.2 15.9 1.3 3.9 10.0 0.6 4.2 0.7 3.0 3.6 3.0 12.5 0.3 3.2 4.1 32.3 0.4 0.7 0.3 0.1 1.6 3.4 15.7 0.0 0.1 41.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 10.8 0.0 0.0 0.0 5.9 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.1 0.0 3.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 1.0 0.0 4.0 0.5 0.1 0.1 0.0 4.8 0.2 0.0 6.3 0.3 0.0 0.0 0.0 7.6 0.1 3.2 0.0 0.2 4.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.1 25.7 14.0 30.7 30.4 25.0 15.3 24.6 15.9 12.5 32.3 15.7 0.4 0.0 0.0 584.1 0.0 0.0 0.0 0.0 0.6 12.4 4.9 1.8 3.3 0.0 0.0 0.0 4.2 1.0 0.0 0.0 9.8 0.0 46.4 1.3 17.7 1.9 0.0 0.0 696.1 0.0 1.3 3.3 0.0 0.4 0.0 0.4 2.5 0.2 0.1 1.7 737.4 0.0 0.0 0.0 0.0 33.2 0.0 0.5 0.0 70.3 0.0 31.3 0.0 1300.8 592.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 2.4 6.6 0.3 18.5 0.9 3.5 1.2 0.0 2.2 0.2 0.1 0.0 0.1 AMPH ENSG00000078053 Amphiphysin P49418 7 38383704-38631420 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 48.9;pituitary gland: 21.3;retina: 65.9" "Group enriched" "Detected in many" 5 "Bipolar cells: 72.2;Cone photoreceptor cells: 87.6;Excitatory neurons: 228.2;Inhibitory neurons: 198.4;Oligodendrocyte precursor cells: 96.5;Rod photoreceptor cells: 59.4" "Cancer enhanced" "Detected in many" "glioma: 3.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 64.6;ASC TERT1: 37.8;BJ hTERT+ SV40 Large T+: 25.4;BJ hTERT+ SV40 Large T+ RasG12V: 29.9;GAMG: 44.8;HBF TERT88: 23.1;U-138 MG: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008559, HPA019828, HPA019829" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Plasma membrane" "CAB008559: AB_1611845, HPA019828: AB_1844801, HPA019829: AB_1844802" "unprognostic (1.76e-2)" "unprognostic (1.59e-1)" "unprognostic (5.94e-2)" "unprognostic (7.36e-2)" "unprognostic (3.24e-3)" "unprognostic (2.92e-1)" "unprognostic (4.90e-2)" "unprognostic (2.55e-2)" "unprognostic (4.37e-1)" "unprognostic (1.08e-1)" "prognostic favorable (9.96e-4)" "unprognostic (5.06e-2)" "unprognostic (5.81e-5)" "unprognostic (1.23e-2)" "unprognostic (5.63e-2)" "unprognostic (8.03e-2)" "unprognostic (1.68e-3)" 6.5 1.3 19.2 1.5 21.9 0.0 5.9 7.2 48.9 5.8 0.0 3.7 0.5 4.0 3.4 3.2 4.7 3.0 5.4 27.3 28.8 2.6 0.4 1.0 0.4 11.2 0.8 0.9 1.8 0.3 21.3 0.0 10.9 1.4 1.4 65.9 2.5 2.9 3.6 1.3 1.8 3.8 7.9 1.9 2.8 2.5 5.4 0.7 1.7 9.6 0.2 2.4 2.9 17.5 0.0 0.0 16.7 0.0 64.6 37.8 0.0 2.4 0.0 25.4 29.9 0.0 0.0 0.0 0.0 4.8 44.8 0.0 0.0 0.0 23.1 0.0 2.0 0.2 0.0 0.0 0.0 0.3 0.1 22.4 0.0 0.0 0.0 0.1 2.0 0.6 0.0 0.5 0.1 0.3 0.0 0.3 8.5 0.0 0.0 0.0 0.0 1.9 0.0 0.1 4.9 0.0 0.0 0.0 0.7 0.5 0.1 0.0 0.0 24.6 17.1 8.8 9.8 0.1 0.3 0.0 16.8 0.3 22.6 0.0 0.2 0.0 0.6 0.0 0.4 0.0 0.2 0.3 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.4 0.0 0.0 19.2 21.9 7.2 48.9 27.3 28.8 11.2 0.8 10.9 7.9 5.4 17.5 0.8 0.0 0.0 22.5 0.6 0.3 0.1 0.0 0.0 72.2 3.1 2.2 7.9 0.0 0.0 0.0 87.6 0.0 0.3 0.0 1.9 0.3 9.9 0.4 3.2 1.1 0.0 0.0 228.2 0.0 0.0 8.6 0.0 0.3 0.0 0.2 3.9 0.1 0.1 1.7 198.4 0.0 0.0 13.0 1.1 15.0 2.8 0.7 0.0 22.5 0.5 7.6 3.1 96.5 5.5 0.1 0.0 4.9 0.1 0.0 0.0 0.0 0.0 59.4 6.6 8.3 8.4 4.7 2.8 0.0 0.3 0.0 0.6 2.0 0.0 0.0 ANK2 "CFAP87, FAP87, LQT4" ENSG00000145362 "Ankyrin 2" Q01484 4 112818032-113384221 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 165.7;retina: 191.2;skeletal muscle: 171.7;tongue: 150.5" "Group enriched" "Detected in many" 4 "Astrocytes: 1101.2;Bipolar cells: 376.6;Cone photoreceptor cells: 479.6;Excitatory neurons: 1282.0;Horizontal cells: 1431.8;Inhibitory neurons: 1060.7;Oligodendrocyte precursor cells: 497.1;Oligodendrocytes: 1351.0;Rod photoreceptor cells: 484.4" "Cancer enhanced" "Detected in many" "glioma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 29.2;ASC TERT1: 32.2;RH-30: 49.6;SH-SY5Y: 24.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008007, CAB015178, HPA035970" Enhanced Approved Supported "Plasma membrane" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB015178: AB_2242828, HPA008007: AB_2667965, HPA035970: AB_2674893" "unprognostic (8.33e-2)" "unprognostic (9.47e-2)" "unprognostic (1.33e-2)" "unprognostic (7.63e-2)" "unprognostic (2.73e-1)" "unprognostic (1.71e-1)" "unprognostic (1.54e-1)" "unprognostic (2.15e-2)" "unprognostic (1.23e-1)" "unprognostic (1.63e-1)" "unprognostic (1.79e-3)" "unprognostic (2.94e-2)" "prognostic unfavorable (2.41e-6)" "unprognostic (1.18e-2)" "unprognostic (3.16e-1)" "unprognostic (1.51e-3)" "unprognostic (2.04e-3)" 31.0 13.6 94.9 11.2 109.0 0.1 18.3 63.1 165.7 31.6 0.0 30.1 8.5 15.8 5.9 12.9 9.6 22.5 119.5 103.9 77.5 110.1 2.4 7.2 9.2 130.2 61.1 27.3 3.2 1.2 19.3 2.1 119.5 7.8 11.4 191.2 6.7 13.3 171.7 8.7 12.7 24.9 51.9 28.3 8.3 9.4 84.8 4.4 9.6 150.5 7.2 9.5 12.3 116.2 0.1 2.9 18.7 5.2 29.2 32.2 0.1 1.5 3.4 0.9 2.6 4.2 0.0 6.9 2.1 5.9 4.1 0.1 11.0 0.6 1.0 2.3 7.3 4.0 0.0 2.9 1.7 1.9 1.2 15.2 3.0 1.2 6.0 3.9 0.0 0.4 0.0 9.3 5.8 0.3 0.2 0.1 9.4 0.1 2.0 0.7 49.6 0.0 0.2 0.0 13.6 24.1 0.2 0.7 8.1 11.7 0.1 1.1 0.0 4.7 2.2 0.4 3.0 6.8 1.8 0.9 20.1 0.6 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.9 109.0 63.1 165.7 103.9 77.5 130.2 61.1 119.5 51.9 84.8 116.2 6.9 0.0 3.9 1101.2 1.1 10.5 0.0 0.0 1.8 376.6 0.2 0.6 188.5 0.0 1.3 20.2 479.6 0.1 0.0 0.0 15.6 0.0 111.2 36.4 6.0 6.4 66.0 0.0 1282.0 1.6 0.1 79.0 2.0 7.2 1.3 81.8 0.0 0.4 1.0 1431.8 1060.7 0.4 8.2 0.0 19.7 49.8 36.4 2.9 17.8 90.9 0.6 44.5 0.0 497.1 1351.0 0.1 5.0 30.1 0.9 0.4 0.1 127.9 0.8 484.4 6.6 24.3 26.5 2.3 1.5 0.8 9.5 0.0 1.9 2.6 0.3 0.2 AOC3 "HPAO, VAP-1, VAP1" ENSG00000131471 "Amine oxidase copper containing 3" Q16853 17 42851184-42858130 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 422.8" "Group enriched" "Detected in many" 4 "Adipocytes: 58.2;Peritubular cells: 74.9;Sertoli cells: 118.3;Smooth muscle cells: 93.0;Theca cells: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 17 "ASC diff: 307.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA000980, CAB025797" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted - unknown location" NA NA 240000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "Golgi apparatus" "CAB025797: , HPA000980: AB_1078170" "unprognostic (2.20e-1)" "unprognostic (4.49e-2)" "prognostic unfavorable (3.68e-4)" "unprognostic (2.97e-2)" "unprognostic (1.17e-1)" "unprognostic (2.64e-1)" "unprognostic (2.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.48e-1)" "unprognostic (4.00e-2)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (1.79e-5)" "unprognostic (5.61e-2)" "unprognostic (1.67e-1)" "unprognostic (8.39e-2)" "prognostic unfavorable (6.98e-4)" 422.8 48.4 2.6 31.9 3.2 1.4 169.2 2.5 4.2 52.8 2.7 210.8 17.3 95.1 33.5 88.0 84.8 50.7 50.2 2.9 2.5 24.1 19.1 218.6 12.4 2.5 2.5 26.5 12.0 8.4 5.4 28.0 2.6 59.1 41.0 1.7 14.7 103.6 17.8 24.6 57.6 144.8 2.3 21.4 66.6 12.8 2.4 5.9 28.2 22.9 3.9 142.1 50.9 2.5 0.1 1.5 0.2 1.0 307.5 0.3 5.0 0.3 0.1 0.2 0.8 0.9 0.0 0.7 0.7 0.1 0.2 0.5 0.8 0.2 0.8 1.5 5.7 0.4 0.5 18.4 0.8 0.3 1.0 3.3 1.0 0.3 0.8 0.0 0.2 2.2 0.3 1.7 0.6 0.2 0.2 1.4 0.7 0.1 0.4 0.7 0.8 3.0 0.1 2.2 0.3 0.4 0.0 0.2 2.0 2.2 0.1 0.1 0.0 0.3 2.7 1.2 0.4 4.8 5.9 0.6 0.4 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.6 3.2 2.5 4.2 2.9 2.5 2.5 2.5 2.6 2.3 2.4 2.5 58.2 3.2 6.0 0.0 0.5 2.9 0.1 0.0 2.2 0.0 1.1 2.2 9.5 0.0 1.9 0.0 0.0 0.1 0.4 0.1 0.0 0.2 4.5 0.8 2.3 12.3 0.0 0.0 0.4 0.2 0.1 11.3 0.0 1.4 1.3 2.1 20.7 0.2 1.4 0.0 0.3 0.1 0.0 1.4 2.7 2.6 3.4 0.9 3.6 3.7 0.0 0.2 0.0 0.0 0.1 0.2 0.0 74.9 0.0 0.4 0.1 1.4 1.0 0.4 118.3 2.6 93.0 1.1 1.3 0.7 1.8 0.3 0.6 74.6 0.1 0.3 ARHGAP28 "FLJ10312, KIAA1314" ENSG00000088756 "Rho GTPase activating protein 28" Q9P2N2 18 6729716-6915716 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "placenta: 25.9;testis: 77.5" "Group enriched" "Detected in many" 14 "Early spermatids: 536.8;Late spermatids: 488.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 4 "neutrophil: 3.0" "Lineage enriched" "Detected in single" 11 "granulocytes: 3.0" "Cell line enhanced" "Detected in many" "AF22: 30.4;CACO-2: 32.8;SuSa: 22.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA030413, HPA030414, HPA030415" Enhanced Supported "Cell Junctions" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 83: Testis - Spermatogenesis" "Cluster 12: NES - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Cell Junctions" "HPA030413: AB_10601455, HPA030414: AB_10670042, HPA030415: AB_10669598" "unprognostic (8.33e-2)" "unprognostic (8.79e-3)" "unprognostic (3.15e-3)" "unprognostic (6.94e-5)" "unprognostic (1.49e-1)" "unprognostic (2.92e-2)" "unprognostic (1.11e-3)" "unprognostic (1.10e-1)" "unprognostic (7.56e-3)" "unprognostic (9.52e-4)" "unprognostic (1.43e-2)" "unprognostic (3.12e-1)" "unprognostic (4.53e-3)" "unprognostic (3.59e-3)" "unprognostic (6.00e-2)" "unprognostic (3.61e-2)" "unprognostic (2.76e-2)" 4.7 1.9 1.1 1.7 1.2 0.8 2.7 1.7 1.6 8.6 0.8 1.9 1.7 2.9 8.7 1.9 3.1 6.6 2.0 1.5 1.6 8.4 0.9 4.6 1.7 0.4 0.2 10.4 3.8 3.0 0.8 25.9 0.5 3.9 2.3 1.4 0.8 2.2 4.9 2.1 1.8 1.4 0.1 12.6 2.1 77.5 1.1 3.8 2.9 1.6 0.9 5.4 3.0 0.8 0.2 0.2 30.4 3.1 6.3 10.5 4.9 2.2 5.1 2.5 5.3 32.8 0.2 0.2 1.0 0.4 1.7 1.4 0.1 0.8 3.7 1.0 1.8 0.1 2.9 0.2 1.1 0.1 0.1 12.6 0.6 2.7 0.2 0.3 7.8 0.5 0.8 2.5 4.1 0.5 0.5 0.3 9.6 0.4 1.4 0.1 2.7 0.2 0.0 2.9 2.9 11.9 0.1 2.8 0.5 22.6 0.2 0.1 1.3 0.5 13.1 10.1 0.4 0.2 0.1 0.1 5.0 0.3 1.1 0.7 0.2 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.1 3.0 0.1 0.0 0.2 0.0 0.0 1.1 1.2 1.7 1.6 1.5 1.6 0.4 0.2 0.5 0.1 1.1 0.8 8.3 0.0 1.9 6.2 0.1 1.9 1.3 0.2 0.0 1.5 0.9 0.5 1.8 0.0 0.7 1.8 20.9 14.9 0.0 0.0 0.0 1.1 536.8 0.5 14.6 7.9 0.0 0.0 7.1 2.7 2.7 16.1 0.0 0.4 0.0 25.8 4.2 0.2 2.1 0.0 34.4 0.1 0.0 0.3 0.4 488.0 18.3 0.5 0.0 12.2 0.0 0.2 0.0 24.6 3.6 0.7 0.0 14.3 0.1 4.7 0.0 3.8 0.0 0.8 0.0 11.0 5.4 14.3 3.7 0.8 1.4 6.6 0.3 23.7 0.0 1.3 ARHGAP6 rhoGAPX-1 ENSG00000047648 "Rho GTPase activating protein 6" O43182 X 11117651-11665920 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 44.3;Microglial cells: 127.4;Oligodendrocyte precursor cells: 60.3;Prostatic glandular cells: 54.4;Sertoli cells: 46.0;Skeletal myocytes: 62.3;Smooth muscle cells: 44.4" "Cancer enhanced" "Detected in many" "prostate cancer: 12.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 26.2;ASC TERT1: 34.2;HEL: 36.4;HMC-1: 24.7;HSkMC: 33.8;K-562: 26.5;RT4: 20.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001798, HPA036779, HPA064390" Enhanced Supported Cytosol "Intracellular and membrane" NA NA 350000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA001798: , HPA036779: AB_10672229, HPA064390: AB_2685253" "unprognostic (2.36e-1)" "unprognostic (1.68e-2)" "unprognostic (3.49e-2)" "unprognostic (7.31e-2)" "unprognostic (6.34e-2)" "unprognostic (1.69e-2)" "unprognostic (4.70e-2)" "unprognostic (2.79e-1)" "unprognostic (1.70e-1)" "unprognostic (7.46e-4)" "unprognostic (1.53e-1)" "unprognostic (1.59e-1)" "prognostic favorable (1.55e-8)" "unprognostic (1.60e-2)" "unprognostic (5.96e-2)" "unprognostic (1.28e-2)" "unprognostic (7.99e-4)" 10.8 1.1 9.0 1.7 5.1 0.7 5.6 2.0 4.2 7.6 3.2 13.9 2.1 10.5 8.2 3.8 8.4 4.2 4.0 5.0 5.8 6.5 0.9 9.6 1.2 3.2 4.0 16.4 1.9 1.2 3.2 7.0 3.2 27.6 3.9 1.0 2.6 30.9 9.6 2.5 4.7 12.9 2.6 5.9 4.1 1.9 6.1 1.0 25.4 8.1 0.8 10.4 5.7 3.8 0.0 0.0 2.4 0.0 26.2 34.2 0.6 0.4 0.6 1.4 0.9 0.4 0.0 0.0 0.0 5.0 0.0 0.1 0.9 0.0 1.2 0.6 0.5 36.4 0.4 0.0 9.7 0.1 24.7 33.8 0.0 2.5 0.1 3.1 0.7 0.1 26.5 12.3 1.5 0.0 0.0 0.2 0.7 0.2 0.4 0.1 11.6 15.7 8.3 20.3 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.4 0.3 1.6 0.7 7.1 0.2 0.7 0.0 0.0 0.5 0.2 4.0 0.2 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.5 9.0 5.1 2.0 4.2 5.0 5.8 3.2 4.0 3.2 2.6 6.1 3.8 9.6 0.0 1.7 10.4 5.3 2.0 16.9 0.3 2.8 4.3 2.3 3.3 4.7 0.0 2.6 33.1 0.0 0.6 0.4 0.0 25.4 0.0 0.1 0.1 5.1 9.2 1.2 2.1 5.5 1.1 0.7 29.1 3.6 0.2 40.0 3.0 8.2 0.0 4.9 0.0 44.3 0.4 0.0 2.2 18.9 0.9 16.1 29.1 5.4 127.4 3.4 7.2 0.0 60.3 3.5 0.7 0.0 10.1 4.9 54.4 0.0 7.4 5.6 0.7 46.0 62.3 44.4 0.2 0.4 4.5 1.7 0.0 1.2 2.1 0.0 22.3 ARMCX1 "ALEX1, GASP7" ENSG00000126947 "Armadillo repeat containing X-linked 1" Q9P291 X 101550547-101554700 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 7.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 74.9;ASC TERT1: 66.9;BJ hTERT+ SV40 Large T+ RasG12V: 78.2;LHCN-M2: 70.7;RH-30: 87.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000268, HPA005685, CAB020695" Supported Supported Nucleoplasm,Mitochondria,Cytosol No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria "Nucleoplasm, Cytosol" "CAB020695: , HPA000268: , HPA005685: AB_10600781" "unprognostic (2.31e-1)" "prognostic unfavorable (3.62e-4)" "unprognostic (2.65e-2)" "unprognostic (2.32e-2)" "unprognostic (2.25e-2)" "unprognostic (2.39e-1)" "unprognostic (2.18e-3)" "unprognostic (2.13e-1)" "unprognostic (1.23e-1)" "unprognostic (1.02e-1)" "prognostic favorable (7.32e-5)" "unprognostic (1.02e-1)" "unprognostic (2.85e-2)" "unprognostic (2.20e-3)" "unprognostic (8.77e-2)" "unprognostic (2.12e-2)" "unprognostic (1.09e-2)" 24.4 34.0 16.8 8.8 18.4 3.1 21.9 14.9 21.9 32.3 18.2 31.4 7.0 30.4 21.2 11.4 25.2 17.5 32.8 18.0 19.5 13.7 4.0 16.5 5.5 16.2 17.9 48.3 12.8 16.9 25.9 14.9 18.8 24.3 7.6 12.0 14.1 23.0 27.7 10.9 12.0 21.2 15.6 14.1 14.8 5.9 17.7 6.3 16.4 25.5 3.4 23.2 21.7 17.9 2.1 0.6 16.0 0.0 74.9 66.9 0.2 25.5 49.7 31.4 78.2 0.0 0.4 0.0 21.3 39.3 34.2 2.1 0.0 3.7 17.7 0.1 0.0 14.9 5.1 0.0 39.6 0.0 0.2 56.5 4.8 23.8 0.0 25.9 19.2 0.0 0.3 0.3 70.7 1.0 0.0 0.1 23.1 0.0 0.2 0.0 87.8 0.1 21.6 0.0 15.8 13.1 0.0 0.3 45.9 4.4 2.5 11.0 25.6 18.9 10.0 55.5 0.3 0.0 0.3 0.0 18.6 0.0 12.1 0.0 3.3 0.4 0.0 3.1 0.5 0.0 0.4 0.3 7.7 0.2 1.1 2.7 0.1 1.8 0.9 4.0 0.8 1.6 16.8 18.4 14.9 21.9 18.0 19.5 16.2 17.9 18.8 15.6 17.7 17.9 27.6 25.6 7.4 8.5 0.7 33.1 22.9 5.0 18.2 32.2 19.1 17.4 59.7 7.2 4.1 23.9 6.2 1.6 3.7 0.6 13.7 21.1 0.3 10.4 23.2 29.9 5.4 4.2 9.5 7.1 2.6 53.2 9.2 11.2 24.1 20.0 20.7 0.8 27.9 21.9 11.8 2.2 2.0 9.5 33.4 2.0 47.2 17.5 58.7 4.7 5.7 36.0 0.0 11.1 8.4 5.6 0.1 44.4 0.4 20.6 0.6 13.6 3.6 13.9 46.0 60.6 39.9 1.6 0.7 3.8 21.7 2.6 2.3 35.6 2.5 7.5 ASIC1 "ACCN2, BNaC2, hBNaC2" ENSG00000110881 "Acid sensing ion channel subunit 1" P78348 12 50057548-50083611 "Predicted membrane proteins" "Calcium transport, Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.9" "Cell type enhanced" "Detected in some" "Astrocytes: 31.3;Inhibitory neurons: 16.4;Oligodendrocyte precursor cells: 64.8;Oligodendrocytes: 11.2" "Cancer enhanced" "Detected in many" "glioma: 12.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 34.8;SH-SY5Y: 27.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058870 Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 68: Oligodendrocytes - Mixed function" "Golgi apparatus, Plasma membrane" "HPA058870: AB_2683841" "unprognostic (5.32e-3)" "unprognostic (1.70e-1)" "unprognostic (4.00e-2)" "unprognostic (3.56e-2)" "unprognostic (2.41e-1)" "unprognostic (3.48e-3)" "unprognostic (2.92e-3)" "unprognostic (3.00e-2)" "unprognostic (1.72e-1)" "unprognostic (9.37e-2)" "unprognostic (2.34e-2)" "unprognostic (2.86e-3)" "unprognostic (6.97e-7)" "unprognostic (7.19e-2)" "unprognostic (3.73e-1)" "unprognostic (2.78e-3)" "unprognostic (8.27e-5)" 1.6 0.7 19.3 0.9 22.2 0.1 1.6 14.4 19.8 3.2 6.4 6.3 0.8 1.9 0.0 2.3 3.0 2.5 2.6 18.2 21.0 0.7 0.2 0.6 0.4 18.0 24.9 1.1 0.5 5.0 0.8 0.6 15.9 2.8 1.2 1.0 3.5 1.9 0.3 0.9 2.5 2.3 13.7 0.3 2.8 0.7 23.7 1.5 0.5 0.0 0.2 1.9 1.7 13.8 3.3 7.2 8.7 19.7 2.7 4.2 4.9 2.2 6.1 4.0 4.0 4.8 2.3 2.1 4.7 1.1 2.4 3.2 8.7 7.7 2.3 1.9 25.1 6.2 9.0 3.2 3.8 9.5 22.7 10.7 3.7 0.4 1.0 34.8 0.5 22.8 4.3 0.0 3.3 4.0 8.8 18.3 3.9 6.9 12.5 9.3 8.5 4.0 2.0 0.1 13.4 27.4 5.3 1.8 3.2 1.4 11.0 6.5 0.3 4.1 12.8 2.5 1.2 0.1 0.0 0.0 5.1 7.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 22.2 14.4 19.8 18.2 21.0 18.0 24.9 15.9 13.7 23.7 13.8 0.3 0.0 0.0 31.3 0.0 0.0 0.4 0.5 0.0 2.8 2.0 2.8 0.9 0.0 2.1 1.8 0.0 0.4 0.1 0.1 0.0 0.2 0.1 0.0 0.7 0.1 0.0 0.0 7.0 0.0 0.9 3.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 3.3 16.4 0.1 0.0 0.0 0.3 0.0 1.5 0.1 0.0 1.9 0.0 1.4 0.0 64.8 11.2 0.2 0.0 1.2 0.2 0.5 0.0 3.2 6.0 0.5 0.0 1.3 0.7 0.1 0.9 2.3 0.0 0.3 0.9 0.4 0.0 0.2 ATRNL1 "ALP, FLJ45344, KIAA0534" ENSG00000107518 "Attractin like 1" Q5VV63 10 115093365-115948999 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 91.1" "Group enriched" "Detected in many" 13 "Excitatory neurons: 2134.6;Inhibitory neurons: 1473.4;Oligodendrocyte precursor cells: 1456.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "cerebral cortex: 91.1;white matter: 58.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 21.4;RH-30: 18.4;U-266/70: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038070 Approved Nucleoplasm,Mitochondria NA NA 160000000 "Cluster 10: Brain - Neuronal signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Mitochondria" "HPA038070: AB_10697237" "unprognostic (3.85e-2)" "unprognostic (1.89e-1)" "unprognostic (5.88e-2)" "unprognostic (3.20e-3)" "unprognostic (1.57e-2)" "unprognostic (3.33e-1)" "unprognostic (1.11e-1)" "unprognostic (1.88e-2)" "unprognostic (5.17e-2)" "unprognostic (4.06e-2)" "unprognostic (2.18e-2)" "unprognostic (2.50e-2)" "unprognostic (1.04e-3)" "unprognostic (3.10e-2)" "unprognostic (2.76e-2)" "unprognostic (1.88e-2)" "unprognostic (2.08e-3)" 0.7 10.7 3.8 0.2 9.5 0.0 1.0 0.0 91.1 0.9 0.0 2.4 0.3 6.2 0.3 0.5 1.0 0.2 1.8 18.3 0.0 2.8 1.5 0.1 0.4 0.0 0.2 9.7 1.3 2.1 5.8 1.9 1.0 3.1 0.2 6.3 1.0 3.8 2.8 0.2 0.8 5.8 0.0 0.3 0.4 12.6 0.0 0.4 1.0 0.0 0.4 0.6 1.0 58.7 0.0 0.6 6.3 21.4 0.0 0.0 0.0 0.1 0.6 3.9 4.6 0.2 0.2 0.0 1.5 0.5 5.1 0.0 1.6 0.0 4.0 0.1 4.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.1 6.4 0.0 11.3 0.0 5.3 10.4 0.2 9.9 0.0 9.1 0.0 0.1 7.5 18.4 11.4 3.9 0.0 3.6 10.5 0.0 0.1 0.4 4.3 1.8 0.0 0.0 0.0 2.7 0.1 3.3 14.2 0.0 4.6 0.1 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 9.5 0.0 91.1 18.3 0.0 0.0 0.2 1.0 0.0 0.0 58.7 0.0 0.0 0.0 55.8 0.8 0.6 0.1 0.8 0.6 35.4 2.1 0.5 2.5 0.0 0.1 0.0 2.1 0.1 0.2 0.2 0.0 0.7 45.6 0.8 1.5 1.5 0.0 0.0 2134.6 0.4 0.0 5.3 0.0 1.8 0.0 24.9 21.0 0.1 3.0 10.1 1473.4 0.0 0.0 1.9 0.4 47.8 1.5 0.3 0.0 128.4 0.0 4.3 0.0 1456.7 34.2 0.3 0.0 0.7 0.0 0.1 0.0 0.5 0.1 4.7 0.0 2.4 2.6 46.6 11.5 0.0 0.1 0.3 0.1 53.1 0.0 0.1 B3GNT9 MGC4655 ENSG00000237172 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9" Q6UX72 16 67148104-67150998 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 12.9;Leydig cells: 11.5;Peritubular cells: 13.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SiHa: 50.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052743, HPA062734" Approved Approved "Nucleoli fibrillar center,Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoli fibrillar center" "HPA052743: AB_2681934, HPA062734: AB_2684854" "unprognostic (2.56e-2)" "unprognostic (2.22e-1)" "unprognostic (2.34e-2)" "unprognostic (1.07e-1)" "unprognostic (6.58e-2)" "unprognostic (1.11e-1)" "unprognostic (1.32e-3)" "unprognostic (3.28e-2)" "unprognostic (3.01e-2)" "unprognostic (1.89e-1)" "unprognostic (1.96e-2)" "unprognostic (2.16e-2)" "unprognostic (1.82e-2)" "unprognostic (1.51e-2)" "unprognostic (1.15e-1)" "unprognostic (4.96e-3)" "unprognostic (7.56e-3)" 7.7 8.4 7.1 4.2 8.0 0.2 5.7 7.5 6.8 15.0 8.4 7.6 3.2 13.4 7.3 5.2 13.7 6.8 13.8 7.1 8.0 7.4 2.5 9.0 2.9 8.7 9.7 15.0 3.5 21.8 20.5 7.9 8.7 11.8 3.3 1.4 9.0 14.8 1.9 5.9 5.6 7.8 9.3 5.6 6.1 6.0 7.7 1.5 18.7 2.1 2.5 11.7 8.9 11.1 4.9 8.8 0.7 0.9 27.7 28.6 1.0 22.5 36.2 14.4 18.5 4.0 0.8 0.6 1.5 34.9 6.0 11.1 0.3 1.0 7.8 7.6 3.2 0.7 9.7 3.5 22.3 0.6 0.5 23.7 8.3 14.0 0.4 35.8 2.0 0.5 1.0 2.7 22.6 2.6 2.6 1.2 5.4 3.8 7.7 7.4 12.9 4.4 2.3 6.0 5.0 11.2 50.9 0.2 0.8 4.3 1.3 3.9 4.6 25.6 1.1 25.9 10.2 3.2 2.4 0.8 31.9 1.3 12.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 7.1 8.0 7.5 6.8 7.1 8.0 8.7 9.7 8.7 9.3 7.7 11.1 1.2 6.4 5.0 1.0 1.2 3.2 2.8 2.4 9.6 1.6 3.2 2.3 2.6 5.7 2.4 3.7 0.0 0.3 0.1 0.4 0.0 1.3 5.3 2.5 7.6 2.0 2.4 0.0 0.4 1.7 0.5 12.9 2.6 2.2 0.0 3.0 6.4 0.1 1.8 0.0 1.3 0.9 2.0 0.6 3.3 6.9 11.5 0.4 1.8 0.0 0.1 0.9 0.0 1.0 2.3 0.9 0.1 13.5 4.7 2.4 0.1 0.9 4.2 0.3 6.6 3.2 6.6 4.4 2.8 2.7 4.1 0.8 1.5 2.9 0.8 1.3 BEND4 "CCDC4, FLJ35632, FLJ43965" ENSG00000188848 "BEN domain containing 4" Q6ZU67 4 42110853-42152878 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.6;prostate: 3.3;testis: 9.4" "Cell type enhanced" "Detected in some" "B-cells: 8.1;Inhibitory neurons: 6.2;Muller glia cells: 10.7;Spermatogonia: 38.3" "Group enriched" "Detected in some" 43 "prostate cancer: 6.3;testis cancer: 5.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 33.2;HEK 293: 7.9;HEL: 21.1;MOLT-4: 13.1;SuSa: 15.4;U-698: 13.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036850 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 36: HEL - Hemostasis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA036850: AB_10600787" "unprognostic (3.62e-4)" "unprognostic (3.82e-1)" "unprognostic (4.82e-2)" "unprognostic (5.96e-3)" "unprognostic (2.97e-3)" "unprognostic (1.10e-1)" "unprognostic (3.81e-2)" "unprognostic (4.00e-1)" "unprognostic (2.97e-1)" "unprognostic (5.58e-2)" "unprognostic (6.71e-3)" "unprognostic (1.68e-1)" "unprognostic (1.54e-5)" "unprognostic (3.48e-1)" "unprognostic (1.49e-1)" "unprognostic (4.58e-3)" "unprognostic (4.24e-1)" 0.0 0.0 0.7 1.1 0.7 0.8 0.0 0.0 1.3 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.0 1.3 1.1 0.0 0.1 0.2 2.1 1.2 3.6 0.1 0.0 0.0 1.0 0.3 2.8 3.3 0.2 1.1 0.0 0.0 0.0 0.0 1.2 0.1 0.1 1.2 0.2 9.4 0.7 1.1 0.0 0.0 1.6 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.6 0.0 33.2 0.0 0.0 0.0 7.9 21.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.4 0.0 7.0 0.0 0.1 0.0 0.0 13.1 0.0 6.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 4.7 0.8 0.0 0.0 0.0 15.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.2 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.7 0.0 1.3 1.3 1.1 1.2 3.6 2.8 0.1 0.7 0.4 0.4 0.0 0.0 0.0 8.1 0.0 0.1 0.0 0.0 1.2 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.6 0.0 3.4 4.4 0.0 0.0 0.3 0.0 0.0 0.0 4.8 2.5 0.0 0.0 3.3 6.2 0.0 0.0 0.0 0.0 1.5 0.0 0.3 0.0 0.0 0.1 10.7 0.0 3.5 0.2 0.0 0.0 0.0 3.9 1.7 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.6 38.3 0.0 0.0 0.0 1.5 2.2 0.0 0.0 BEND5 "C1orf165, FLJ11588" ENSG00000162373 "BEN domain containing 5" Q7L4P6 1 48727519-48776969 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 54.8;Proximal tubular cells: 30.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 6.5;naive B-cell: 8.0" "Lineage enriched" "Detected in many" 5 "B-cells: 8.0" "Cell line enhanced" "Detected in some" "AF22: 3.4;HDLM-2: 11.7;JURKAT: 4.5;MOLT-4: 4.8;REH: 6.5;SH-SY5Y: 2.9" "Low region specificity" "Detected in many" "HPA054347, HPA058007" Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nuclear speckles" Cytosol "HPA054347: AB_2682456, HPA058007: AB_2683577" "prognostic favorable (2.50e-5)" "unprognostic (1.36e-2)" "unprognostic (7.19e-3)" "unprognostic (1.16e-1)" "unprognostic (1.11e-1)" "unprognostic (1.65e-2)" "unprognostic (4.42e-2)" "prognostic favorable (1.29e-4)" "unprognostic (1.41e-1)" "unprognostic (6.02e-2)" "prognostic favorable (1.29e-4)" "unprognostic (1.32e-2)" "unprognostic (4.28e-2)" "unprognostic (2.37e-3)" "unprognostic (3.35e-2)" "unprognostic (9.68e-2)" "prognostic favorable (8.30e-6)" 1.7 1.9 5.1 0.7 5.1 1.0 1.8 4.1 7.4 2.8 4.1 3.4 0.4 2.0 1.5 0.6 2.5 2.0 1.6 5.1 4.3 3.4 0.1 0.9 2.1 6.3 5.0 4.4 1.7 1.8 3.4 0.3 6.4 1.5 0.4 3.7 1.0 1.2 2.6 0.8 1.6 0.7 4.1 2.7 1.7 1.0 4.8 4.8 1.8 1.7 1.4 2.2 1.7 5.3 0.0 0.0 3.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.1 0.0 4.8 0.2 2.6 0.0 0.0 6.5 1.1 0.0 0.0 1.2 1.1 2.9 0.0 0.0 0.2 1.2 0.0 0.3 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.2 1.7 8.0 1.6 1.0 0.2 1.2 0.0 1.7 0.0 0.4 5.1 5.1 4.1 7.4 5.1 4.3 6.3 5.0 6.4 4.1 4.8 5.3 8.7 6.4 3.1 0.0 17.2 1.9 4.6 4.6 1.8 13.3 4.0 16.9 8.6 8.6 6.1 5.5 16.7 0.3 0.6 0.5 54.8 6.4 8.9 2.7 1.9 6.9 12.1 0.8 0.0 1.8 0.5 8.4 2.6 1.3 1.3 10.2 4.6 0.2 0.3 8.4 0.0 0.8 2.0 0.6 4.4 7.1 13.1 1.5 3.6 0.0 0.5 22.7 0.0 0.0 0.0 2.6 4.5 21.4 7.6 1.1 0.2 30.2 6.4 17.8 6.6 6.8 5.6 3.7 9.1 0.3 2.3 0.1 2.8 11.4 1.6 1.9 BMPR1B "ALK6, CDw293" ENSG00000138696 "Bone morphogenetic protein receptor type 1B" O00238 4 94757955-95158448 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Chondrogenesis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.1;cervix: 24.7;prostate: 22.4" "Cell type enriched" "Detected in many" 7 "Astrocytes: 480.6" "Cancer enhanced" "Detected in many" "breast cancer: 32.4;prostate cancer: 24.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 22.0;MCF7: 11.1;SH-SY5Y: 18.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (2.25e-1)" "unprognostic (1.80e-2)" "unprognostic (1.40e-3)" "prognostic favorable (2.84e-4)" "unprognostic (1.57e-1)" "unprognostic (4.22e-2)" "unprognostic (1.92e-1)" "unprognostic (2.86e-2)" "unprognostic (2.95e-2)" "unprognostic (1.01e-1)" "unprognostic (3.97e-2)" "unprognostic (3.93e-1)" "unprognostic (1.62e-3)" "unprognostic (7.89e-4)" "unprognostic (6.22e-2)" "unprognostic (3.81e-3)" "unprognostic (2.63e-2)" 0.7 4.6 13.4 0.3 15.4 0.1 1.0 13.5 15.0 24.7 2.1 0.9 0.1 4.4 2.4 0.2 12.5 2.6 0.8 12.5 16.0 7.8 0.8 1.7 0.0 19.3 20.1 6.2 1.1 0.1 1.9 0.7 17.5 22.4 0.2 8.1 1.0 14.2 3.0 0.8 0.1 0.6 15.3 0.9 2.4 3.7 15.6 6.4 0.5 1.1 0.0 0.2 0.5 12.1 0.0 22.0 5.6 0.0 2.3 4.8 0.2 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.2 1.0 0.0 1.3 3.6 8.4 0.1 0.0 4.9 0.0 1.4 0.0 0.6 0.5 0.1 2.7 9.0 2.8 6.2 0.4 0.1 0.0 0.0 0.0 7.1 11.1 0.6 0.1 2.1 0.1 3.2 0.2 3.4 0.1 4.3 0.1 0.2 18.8 0.3 3.2 3.2 0.8 1.7 0.0 0.0 4.0 3.8 0.2 4.3 0.0 0.0 0.0 1.5 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.0 13.4 15.4 13.5 15.0 12.5 16.0 19.3 20.1 17.5 15.3 15.6 12.1 0.0 6.4 0.0 480.6 0.0 2.7 1.3 13.1 1.2 0.4 3.8 1.0 3.4 2.8 33.4 60.7 0.0 0.0 0.0 0.0 1.9 3.0 1.4 28.5 1.4 1.1 18.4 0.0 51.0 0.4 0.3 1.5 0.0 20.8 0.0 38.6 2.9 0.0 0.1 0.0 2.5 0.0 8.2 0.0 1.2 1.4 3.1 0.4 28.4 22.5 0.0 38.5 0.0 10.1 2.8 0.7 0.0 3.8 0.0 28.5 0.0 0.2 15.7 1.6 0.0 1.7 2.9 1.2 10.6 0.4 2.3 0.0 0.5 4.4 0.0 1.6 BRINP1 "DBC1, DBCCR1, FAM5A" ENSG00000078725 "BMP/retinoic acid inducible neural specific 1" O60477 9 119153458-119369435 "Predicted intracellular proteins, Transporters" "Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 43.5" "Group enriched" "Detected in some" 8 "Astrocytes: 178.9;Excitatory neurons: 285.7;Inhibitory neurons: 163.4;Oligodendrocyte precursor cells: 204.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 8.6;NTERA-2: 17.0;SCLC-21H: 7.4;SH-SY5Y: 3.2;SuSa: 6.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038828 Approved Uncertain Microtubules "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Microtubules "HPA038828: AB_10670909" "unprognostic (8.60e-5)" "unprognostic (2.31e-2)" "unprognostic (1.24e-1)" "unprognostic (5.09e-5)" "unprognostic (1.12e-1)" "unprognostic (1.14e-2)" "unprognostic (1.37e-1)" "unprognostic (2.98e-1)" "unprognostic (1.76e-1)" "unprognostic (1.02e-1)" "unprognostic (2.28e-4)" "unprognostic (1.51e-2)" "unprognostic (5.06e-3)" "unprognostic (1.39e-3)" "unprognostic (1.56e-1)" "unprognostic (7.59e-2)" "unprognostic (1.41e-1)" 0.1 3.8 28.8 0.0 23.3 0.0 2.4 20.5 43.5 0.5 0.0 0.2 0.2 0.7 4.9 0.6 0.0 1.4 1.8 35.7 17.8 1.7 0.6 1.9 0.0 9.6 20.6 0.1 0.0 0.0 1.6 0.0 16.8 1.5 0.1 5.3 0.7 5.2 0.3 0.1 0.6 0.1 16.0 0.3 0.2 0.5 27.7 0.8 0.3 0.1 0.0 0.3 0.2 18.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 17.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 7.4 3.2 0.0 0.0 0.0 6.0 0.6 0.0 0.0 1.1 1.8 0.0 0.8 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.8 23.3 20.5 43.5 35.7 17.8 9.6 20.6 16.8 16.0 27.7 18.8 0.1 0.0 0.0 178.9 0.0 0.0 0.5 0.5 0.0 8.7 8.1 4.2 0.9 0.0 0.1 0.0 25.0 0.1 0.0 0.3 0.0 0.0 2.1 0.5 15.9 0.5 2.4 0.0 285.7 0.0 0.0 0.4 0.0 0.4 0.0 0.2 2.9 0.0 0.3 1.7 163.4 0.0 0.0 0.3 0.0 1.0 0.0 0.3 0.0 8.4 0.0 1.6 0.0 204.6 4.9 0.1 0.0 0.4 0.0 0.4 0.0 23.9 0.0 2.6 0.0 0.0 0.4 1.0 1.7 0.0 0.0 0.0 0.2 0.1 0.0 0.3 BVES "HBVES, POP1, POPDC1" ENSG00000112276 "Blood vessel epicardial substance" Q8NE79 6 105096822-105137157 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion" "Developmental protein" "Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 27.8;skeletal muscle: 43.9;tongue: 29.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 34.2;Early spermatids: 36.1;Late spermatids: 55.3;Oligodendrocytes: 17.8;Spermatocytes: 24.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 29.7;WM-115: 30.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA014788, HPA018176" Enhanced Supported "Plasma membrane,Cell Junctions" Yes NA "Cluster 17: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cell Junctions" "HPA014788: AB_1845504, HPA018176: AB_1845503" "unprognostic (2.91e-1)" "unprognostic (2.45e-1)" "unprognostic (2.79e-2)" "unprognostic (1.73e-2)" "unprognostic (5.46e-2)" "unprognostic (3.66e-2)" "unprognostic (5.21e-2)" "unprognostic (2.22e-2)" "unprognostic (8.37e-2)" "unprognostic (4.49e-2)" "unprognostic (2.29e-2)" "unprognostic (8.92e-2)" "unprognostic (5.84e-3)" "unprognostic (3.77e-2)" "unprognostic (1.78e-1)" "unprognostic (2.02e-2)" "unprognostic (3.24e-4)" 2.9 0.7 2.6 2.3 7.1 0.2 1.5 5.8 3.6 2.5 4.6 14.9 1.4 5.8 1.7 5.3 2.8 1.8 27.8 2.7 4.3 1.6 0.3 1.9 0.6 7.3 5.6 1.0 0.6 0.7 2.4 3.5 7.4 5.2 3.3 0.2 1.4 10.0 43.9 0.7 3.0 17.7 5.2 0.3 6.9 11.5 5.2 0.2 1.3 29.3 0.4 9.3 2.2 10.8 1.3 2.0 7.6 1.3 10.9 14.9 3.3 5.8 4.1 8.8 11.6 0.5 0.0 0.0 0.0 10.9 14.7 0.1 3.3 2.0 8.1 0.0 2.8 0.0 1.0 0.3 2.4 0.0 0.6 8.7 6.9 13.6 1.1 6.6 4.0 3.3 0.1 19.3 19.7 0.1 0.2 1.0 1.6 0.0 0.0 5.7 29.7 0.0 0.0 0.0 9.9 17.1 3.7 0.1 7.7 5.5 0.0 20.0 8.9 14.0 0.0 0.0 15.3 1.8 0.8 0.0 8.3 0.0 30.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 2.6 7.1 5.8 3.6 2.7 4.3 7.3 5.6 7.4 5.2 5.2 10.8 2.1 0.0 0.0 1.6 0.0 0.3 0.4 0.1 0.6 0.0 0.4 1.0 34.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 36.1 1.9 4.4 3.1 0.0 0.0 3.3 0.0 0.2 2.6 0.0 6.0 0.0 0.9 2.2 0.1 2.3 0.0 0.6 0.0 0.0 0.0 1.9 55.3 1.2 0.5 0.0 3.7 1.0 0.0 0.0 5.0 17.8 0.1 0.0 3.4 0.0 0.5 0.1 0.1 0.1 0.0 13.1 11.8 4.4 24.4 5.4 0.1 0.9 0.1 0.2 1.3 0.0 0.3 C7 ENSG00000112936 "Complement C7" P10643 5 40909497-40984643 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 735.4" "Group enriched" "Detected in many" 4 "Fibroblasts: 578.4;Hepatic stellate cells: 662.5;Leydig cells: 1058.5;Sertoli cells: 309.0;Theca cells: 503.1" "Cancer enriched" "Detected in all" 4 "pancreatic cancer: 73.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "ASC diff: 116.5;HHSteC: 155.1;HSkMC: 212.1;SH-SY5Y: 146.7" "Not detected" "Not detected" "Region enhanced" "Detected in many" "spinal cord: 13.7" HPA001465 Approved "Secreted to blood" NA NA 48000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA001465: AB_1078554" "unprognostic (5.01e-2)" "unprognostic (3.74e-2)" "unprognostic (7.40e-2)" "unprognostic (4.68e-3)" "unprognostic (5.35e-2)" "unprognostic (1.43e-3)" "prognostic favorable (5.89e-4)" "unprognostic (6.67e-2)" "unprognostic (3.45e-1)" "unprognostic (2.21e-2)" "unprognostic (1.33e-1)" "unprognostic (1.93e-3)" "unprognostic (2.24e-2)" "unprognostic (6.10e-3)" "unprognostic (1.12e-1)" "unprognostic (2.14e-1)" "unprognostic (2.06e-3)" 470.9 607.7 2.6 21.7 3.5 0.2 46.4 2.6 9.6 118.5 13.6 165.3 19.3 124.6 163.6 52.9 377.3 211.7 558.7 2.8 2.5 298.1 110.6 206.7 99.2 4.4 2.7 735.4 149.8 15.0 23.1 359.2 3.0 101.6 32.5 1.5 18.0 105.7 4.3 12.6 139.8 256.3 4.3 138.2 120.2 28.0 3.0 32.2 105.1 1.6 22.5 122.1 118.3 3.0 0.0 0.0 0.0 0.0 116.5 16.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 155.1 0.0 0.0 212.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 146.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.6 3.5 2.6 9.6 2.8 2.5 4.4 2.7 3.0 4.3 3.0 3.0 7.9 6.4 4.1 0.0 1.4 0.6 0.5 0.0 1.8 2.1 1.2 0.3 56.7 7.2 2.5 0.0 0.0 0.2 0.1 0.4 0.0 0.2 4.7 0.5 7.9 127.6 54.8 26.7 0.1 1.3 0.1 578.4 0.0 0.2 1.3 2.7 662.5 8.3 0.5 43.7 0.3 1.3 0.0 14.5 4.2 29.8 1058.5 1.5 0.0 58.1 0.6 3.7 0.0 0.0 0.0 0.9 0.9 18.0 1.0 1.3 0.2 0.1 0.0 0.9 309.0 2.2 23.7 2.6 2.5 6.5 0.6 0.3 1.2 503.1 3.0 0.8 CAMK4 "CaMK-GR, CaMKIV" ENSG00000152495 "Calcium/calmodulin dependent protein kinase IV" Q16566 5 111223653-111494886 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Inflammatory response" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 70.4;lymphoid tissue: 55.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 70.9;Early spermatids: 306.2;Excitatory neurons: 212.2;Inhibitory neurons: 131.8;Late spermatids: 108.4;Oligodendrocyte precursor cells: 133.2;T-cells: 83.3" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 6 "basal ganglia: 30.6;cerebellum: 70.4" "Group enriched" "Detected in many" 4 "MAIT T-cell: 24.3;memory CD4 T-cell: 17.3;memory CD8 T-cell: 13.5;naive CD4 T-cell: 33.1;naive CD8 T-cell: 18.5;T-reg: 21.3" "Lineage enriched" "Detected in many" 23 "T-cells: 33.1" "Cell line enhanced" "Detected in many" "HDLM-2: 88.9;JURKAT: 61.3;MOLT-4: 27.9;SH-SY5Y: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004347, HPA011753, HPA017206" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Nucleoplasm, Nucleoli fibrillar center" "CAB004347: AB_626793, HPA011753: AB_1845950, HPA017206: AB_1845949" "unprognostic (2.99e-5)" "unprognostic (7.19e-2)" "unprognostic (3.43e-3)" "unprognostic (5.11e-2)" "unprognostic (4.75e-3)" "unprognostic (3.48e-2)" "unprognostic (7.66e-4)" "unprognostic (7.22e-3)" "unprognostic (2.49e-1)" "unprognostic (2.92e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (2.23e-5)" "unprognostic (2.42e-2)" "unprognostic (3.01e-2)" "unprognostic (1.66e-1)" "unprognostic (9.99e-3)" 0.4 3.8 5.0 4.4 30.6 3.1 0.4 70.4 8.2 0.9 0.0 1.3 1.4 0.6 0.3 0.7 0.3 1.5 0.1 7.6 0.0 0.7 1.4 1.1 8.1 0.0 0.4 0.6 0.4 0.0 0.6 0.2 1.4 3.4 1.4 4.7 0.4 1.4 0.1 0.1 2.3 0.8 0.0 2.6 1.5 9.4 0.8 55.4 0.2 0.0 5.2 1.7 0.4 0.0 0.0 0.0 3.1 2.1 0.6 2.3 0.0 0.8 6.8 8.0 7.8 0.0 0.1 0.0 4.0 0.4 5.4 0.3 6.8 0.8 5.8 88.9 5.2 1.3 2.8 0.0 0.2 0.6 0.3 0.3 0.0 16.8 1.7 4.9 1.4 61.3 0.0 3.3 0.4 0.0 27.9 0.0 4.1 0.0 0.2 4.0 5.0 0.2 2.9 0.1 18.8 33.5 1.2 0.0 5.6 0.2 0.1 0.5 0.1 16.3 9.5 0.1 14.7 2.6 0.3 0.0 8.0 0.0 6.3 0.1 0.0 0.0 4.8 0.0 24.3 1.3 17.3 13.5 0.0 0.3 33.1 18.5 0.9 1.4 0.0 0.1 21.3 5.5 5.0 30.6 70.4 8.2 7.6 0.0 0.0 0.4 1.4 0.0 0.8 0.0 1.8 0.0 1.1 57.8 9.4 1.1 0.3 1.3 8.6 70.9 0.6 0.6 5.3 0.0 0.0 0.0 0.0 0.1 3.1 0.1 0.0 0.1 306.2 0.2 1.6 1.1 0.0 0.0 212.2 0.0 0.2 4.6 3.6 0.4 4.5 0.3 0.7 0.3 0.2 0.0 131.8 0.8 0.0 1.3 2.1 108.4 4.1 2.0 0.0 12.2 2.7 2.8 1.0 133.2 5.4 1.2 0.0 1.5 11.5 0.5 0.0 0.1 0.1 4.3 0.0 0.6 3.8 30.3 6.2 2.4 1.0 0.0 83.3 0.1 0.0 0.3 CAV1 CAV ENSG00000105974 "Caveolin 1" Q03135 7 116524994-116561179 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Cancer-related genes, Congenital generalized lipodystrophy, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 2160.5;Alveolar cells type 1: 3557.7;Basal keratinocytes: 1375.3;Endothelial cells: 1024.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "basophil: 14.6;memory B-cell: 5.1" "Group enriched" "Detected in many" 57 "B-cells: 5.1;granulocytes: 14.6" "Cell line enhanced" "Detected in many" "ASC TERT1: 2140.5;BJ hTERT+: 2371.6;HBEC3-KT: 2333.7;LHCN-M2: 2372.1;U-138 MG: 1894.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 122.1" "CAB003791, HPA049326" Enhanced Supported "Golgi apparatus" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "CAB003791: AB_562068, HPA049326: AB_2680714" "unprognostic (5.98e-2)" "unprognostic (1.35e-3)" "unprognostic (3.35e-1)" "unprognostic (5.37e-2)" "unprognostic (4.62e-3)" "unprognostic (2.35e-3)" "unprognostic (8.07e-2)" "prognostic unfavorable (7.17e-5)" "unprognostic (1.31e-1)" "unprognostic (2.25e-1)" "unprognostic (1.79e-3)" "unprognostic (7.92e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.65e-3)" "unprognostic (2.72e-1)" "unprognostic (7.40e-2)" "unprognostic (6.14e-3)" 621.1 17.4 12.7 44.7 15.3 0.6 284.5 14.3 21.6 267.0 11.8 298.8 32.3 190.9 72.5 135.1 152.5 148.2 276.5 12.2 13.9 18.4 26.6 592.0 30.3 15.1 13.4 137.4 24.6 21.4 6.8 449.2 14.6 110.3 93.6 31.4 58.0 175.5 102.9 104.9 89.4 274.2 14.3 199.1 120.8 25.8 16.1 25.2 168.4 184.6 20.3 202.0 124.1 16.2 458.7 344.3 9.5 3.7 1406.6 2140.5 20.6 1055.8 2371.6 566.0 591.2 3.0 652.4 0.1 365.8 1228.5 494.8 828.2 2.2 2333.7 840.3 36.0 19.5 0.4 128.7 0.3 196.9 0.1 2.1 736.9 481.6 805.7 536.0 539.0 1749.9 0.2 0.3 23.4 2372.1 45.2 0.5 0.8 33.7 1.2 173.9 5.2 25.2 251.0 317.0 2.0 1.0 0.6 328.3 20.1 52.3 137.8 1.6 3.9 1349.3 1894.8 212.4 730.6 298.9 96.8 15.8 1.9 758.4 0.9 701.0 14.6 0.0 0.0 0.0 0.0 0.0 5.1 0.1 0.1 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.8 12.7 15.3 14.3 21.6 12.2 13.9 15.1 13.4 14.6 14.3 16.1 16.2 2160.5 3557.7 123.0 0.0 15.8 1375.3 392.0 534.8 316.4 8.3 17.9 190.8 286.6 107.2 342.0 7.3 2.1 64.3 7.0 0.3 5.9 76.8 2.6 17.5 102.3 1024.0 1.8 16.0 0.4 0.7 449.5 326.8 1.5 21.3 13.9 6.3 450.5 5.2 15.0 0.0 0.5 7.0 20.3 11.0 187.1 13.4 377.2 10.7 439.4 19.7 3.7 249.0 0.0 1.0 1.3 43.1 0.1 565.4 56.2 512.7 0.7 0.3 30.6 7.7 558.8 152.4 751.4 2.1 5.7 39.4 610.9 117.0 16.7 59.7 2.4 93.3 CCDC102B "ACY1L, AN, C18orf14, FLJ23594, HsT1731" ENSG00000150636 "Coiled-coil domain containing 102B" Q68D86 18 68715209-69055189 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 28.4" "Cell type enhanced" "Detected in many" "Astrocytes: 72.8;Early spermatids: 138.2;Excitatory neurons: 80.8;Late spermatids: 83.3;Oligodendrocytes: 90.1;Sertoli cells: 78.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 9.1" "Lineage enriched" "Detected in many" 5 "dendritic cells: 9.1" "Cell line enhanced" "Detected in many" "ASC TERT1: 14.2;BJ hTERT+: 29.0;fHDF/TERT166: 26.2;HSkMC: 15.4;Karpas-707: 10.2" "HPA040623, HPA048194" Approved Approved Mitochondria,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria Cytosol "HPA040623: AB_10805715, HPA048194: AB_2680309" "unprognostic (3.92e-2)" "unprognostic (1.62e-1)" "unprognostic (5.58e-2)" "unprognostic (9.50e-3)" "unprognostic (7.13e-2)" "unprognostic (3.50e-1)" "unprognostic (7.87e-3)" "unprognostic (1.36e-1)" "unprognostic (5.59e-2)" "unprognostic (8.62e-3)" "unprognostic (1.95e-1)" "unprognostic (6.04e-2)" "prognostic unfavorable (2.90e-6)" "unprognostic (2.21e-2)" "unprognostic (2.12e-2)" "unprognostic (8.00e-3)" "unprognostic (3.13e-3)" 7.1 2.9 1.5 3.7 1.8 0.7 2.7 0.6 3.5 2.8 0.0 3.8 1.5 1.7 1.1 3.4 1.8 13.6 3.2 1.3 2.0 4.3 1.7 14.3 8.6 2.6 1.6 0.9 1.5 2.6 0.9 28.4 3.1 1.2 4.5 2.2 1.3 1.3 0.6 1.0 2.6 3.7 2.0 2.2 3.6 2.0 2.3 1.5 5.2 1.1 2.0 10.6 1.5 3.6 0.0 0.0 4.0 0.3 3.6 14.2 0.2 0.8 29.0 0.3 0.5 0.1 0.4 0.1 0.6 26.2 0.5 0.4 0.1 0.2 0.4 1.2 0.4 0.8 0.0 1.3 7.0 0.1 0.4 15.4 0.6 0.4 3.5 0.6 0.2 2.0 0.0 10.2 2.4 0.0 0.6 0.3 0.8 0.2 0.5 1.3 0.2 0.5 0.1 0.0 1.7 1.5 0.1 0.0 0.1 1.6 0.3 1.3 4.0 0.6 0.2 0.2 0.3 4.4 0.3 0.8 2.1 1.7 2.5 0.0 0.1 0.3 1.0 0.2 0.9 0.5 0.6 0.8 0.2 0.6 1.8 1.1 0.0 1.0 0.2 9.1 0.3 0.3 1.5 1.8 0.6 3.5 1.3 2.0 2.6 1.6 3.1 2.0 2.3 3.6 11.5 0.0 2.2 72.8 4.4 0.6 0.8 0.8 0.6 6.4 2.7 2.9 10.0 0.0 2.1 3.7 6.2 0.8 12.4 0.4 5.9 0.7 138.2 2.9 6.7 6.8 0.0 3.0 80.8 1.8 0.6 15.3 0.0 1.1 2.5 5.7 8.6 0.8 3.2 6.7 33.6 0.2 0.0 1.9 1.8 83.3 32.3 3.3 0.0 44.0 2.1 11.9 7.2 36.2 90.1 0.2 2.6 9.1 2.2 0.4 0.3 5.3 1.5 13.4 78.9 3.8 37.3 1.9 5.7 0.7 0.6 0.3 3.8 3.7 0.4 0.6 CCDC80 "CL2, DRO1, LINC01279, SSG1, TCONS_00006930, URB" ENSG00000091986 "Coiled-coil domain containing 80" Q76M96 3 112596797-112649530 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 450.8;Fibroblasts: 921.6;Late spermatids: 353.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 521.4;fHDF/TERT166: 1281.3;hTERT-RPE1: 2404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002266 Approved "Secreted to extracellular matrix" NA NA 510000 "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA002266: AB_1078423" "unprognostic (1.26e-1)" "unprognostic (1.89e-1)" "unprognostic (1.26e-2)" "unprognostic (3.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.50e-1)" "unprognostic (2.82e-1)" "unprognostic (2.53e-2)" "unprognostic (2.30e-3)" "unprognostic (1.99e-3)" "unprognostic (8.40e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (2.86e-5)" "unprognostic (5.97e-3)" "unprognostic (1.65e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.26e-4)" 244.9 15.0 6.4 83.5 6.9 1.1 218.3 9.6 8.6 305.3 24.4 74.5 8.7 276.5 76.8 92.4 82.2 234.0 218.8 6.8 10.2 17.7 6.6 74.0 18.5 12.2 11.4 62.2 28.7 12.4 10.8 26.0 9.3 67.8 73.4 9.4 34.7 78.7 13.4 79.1 25.1 360.3 11.1 34.8 47.5 42.7 9.2 17.1 87.5 34.9 30.8 194.4 131.8 13.5 26.1 11.0 127.6 5.8 521.4 411.2 6.9 359.0 108.5 118.6 171.8 2.9 2.1 1.2 13.5 1281.3 11.4 33.5 5.3 4.8 123.7 24.3 1.2 0.7 27.7 0.7 109.5 1.0 0.5 409.7 14.4 174.9 11.0 2404.9 27.8 0.6 0.4 1.0 352.7 0.5 0.3 0.7 31.6 0.7 4.2 0.3 14.0 0.6 3.3 0.5 0.4 2.5 53.5 2.3 1.8 23.0 2.1 1.0 141.7 345.6 56.6 66.6 160.1 1.6 0.8 1.2 102.4 0.7 56.8 0.9 0.3 0.2 0.3 0.1 0.3 0.4 0.3 0.3 0.1 0.6 0.4 0.4 0.3 0.3 0.2 0.7 0.2 0.0 6.4 6.9 9.6 8.6 6.8 10.2 12.2 11.4 9.3 11.1 9.2 13.5 104.5 6.4 15.9 13.1 1.5 60.9 4.2 44.7 26.7 1.1 5.9 59.7 22.5 10.0 62.7 5.5 0.0 57.9 1.0 0.3 1.9 23.7 450.8 95.4 93.2 43.9 0.0 0.0 1.0 1.2 101.5 921.6 16.8 18.4 1.3 44.3 53.6 0.9 9.4 0.0 0.3 0.8 30.5 2.2 121.5 353.6 77.0 9.7 144.1 3.7 2.0 101.4 0.0 0.0 0.0 13.5 0.0 34.6 5.8 3.6 0.0 0.1 112.4 2.5 19.7 177.7 198.4 6.9 4.9 11.9 51.7 27.9 9.0 23.0 0.1 1.9 CCN2 "CTGF, IGFBP8" ENSG00000118523 "Cellular communication network factor 2" P29279 6 131948176-131951372 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cell adhesion, DNA synthesis" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 101.2;Cardiomyocytes: 38.7;Extravillous trophoblasts: 47.1;Fibroblasts: 261.8;Smooth muscle cells: 104.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "naive B-cell: 8.1" "Lineage enriched" "Detected in single" 81 "B-cells: 8.1" "Cell line enhanced" "Detected in many" "EFO-21: 1605.0;HUVEC TERT2: 1377.0;TIME: 2874.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005123, HPA031074, HPA031075" Approved Approved "Golgi apparatus,Vesicles" "Secreted in other tissues" No No 1010000 5900000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "CAB005123: AB_638805, HPA031074: AB_10599618, HPA031075: AB_10611248" "unprognostic (2.87e-1)" "unprognostic (1.43e-1)" "unprognostic (4.41e-2)" "unprognostic (5.68e-2)" "unprognostic (9.79e-2)" "unprognostic (1.82e-2)" "unprognostic (3.38e-1)" "unprognostic (4.96e-2)" "unprognostic (1.68e-1)" "unprognostic (3.89e-2)" "unprognostic (2.39e-1)" "unprognostic (2.06e-1)" "unprognostic (1.27e-3)" "prognostic unfavorable (5.04e-4)" "unprognostic (1.62e-1)" "unprognostic (1.77e-2)" "unprognostic (3.84e-3)" 265.9 107.5 18.9 168.0 18.8 2.0 206.4 16.3 34.0 531.0 31.5 148.8 43.7 418.5 34.4 271.9 243.8 441.4 371.8 25.8 14.2 235.7 82.9 226.3 73.6 18.8 32.1 77.0 194.0 43.0 44.8 198.2 20.2 364.6 136.1 2.4 138.2 154.3 51.8 155.1 151.2 576.3 14.2 569.1 182.6 24.7 20.8 49.5 464.7 61.9 14.9 324.0 102.5 18.2 4.6 7.5 126.8 3.7 279.9 158.5 1.8 373.1 178.2 226.8 119.4 0.2 12.2 0.6 1605.0 482.7 185.0 6.2 4.2 26.4 211.3 2.5 3.5 0.2 55.7 137.3 109.6 0.3 0.5 232.2 5.9 163.9 40.2 340.7 1377.0 0.0 0.4 0.3 650.8 2.5 0.5 1.2 61.8 41.3 21.7 32.6 6.0 0.7 81.9 0.4 0.5 0.8 38.3 62.2 18.3 308.5 6.1 3.1 2874.4 311.6 242.4 397.8 694.0 11.5 1.7 4.1 42.5 0.7 399.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 18.9 18.8 16.3 34.0 25.8 14.2 18.8 32.1 20.2 14.2 20.8 18.2 101.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.7 0.0 0.0 0.0 0.0 17.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 0.0 0.0 47.1 261.8 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 104.4 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 CD109 "CPAMD7, DKFZp762L1111, FLJ38569" ENSG00000156535 "CD109 molecule" Q6YHK3 6 73695785-73828316 "CD markers, Plasma proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "parathyroid gland: 330.4" "Cell type enhanced" "Detected in many" "Adipocytes: 65.3;Basal respiratory cells: 62.8;Hofbauer cells: 45.0;Squamous epithelial cells: 51.4;Suprabasal keratinocytes: 43.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 206.4;BJ hTERT+: 126.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008992, HPA015723" Enhanced Supported "Plasma membrane,Cytosol" NA NA 180000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA008992: , HPA015723: AB_2732415" "unprognostic (2.28e-1)" "unprognostic (1.03e-1)" "unprognostic (7.76e-2)" "unprognostic (1.52e-2)" "unprognostic (9.17e-3)" "unprognostic (1.36e-1)" "unprognostic (1.03e-3)" "unprognostic (1.23e-3)" "unprognostic (7.49e-2)" "unprognostic (2.47e-1)" "unprognostic (1.15e-3)" "unprognostic (8.81e-2)" "prognostic unfavorable (2.65e-4)" "prognostic unfavorable (7.96e-5)" "unprognostic (9.50e-2)" "unprognostic (2.02e-1)" "prognostic unfavorable (4.68e-4)" 8.6 1.1 2.3 2.4 2.5 2.8 5.5 2.1 2.1 9.9 0.7 6.9 1.3 12.5 5.6 10.2 3.2 4.1 5.8 2.0 4.0 7.0 1.1 6.6 1.0 3.2 3.6 0.7 0.5 330.4 0.4 6.5 3.5 3.6 2.9 0.2 3.4 2.5 1.2 18.9 2.2 12.6 3.7 2.1 1.1 1.8 2.5 3.1 1.3 3.3 2.2 4.5 7.4 3.1 35.6 29.4 1.5 0.1 48.2 206.4 0.0 30.5 126.0 9.0 18.4 0.1 20.2 0.0 19.7 63.5 19.5 96.5 3.5 60.9 12.1 8.5 5.5 11.5 21.0 5.8 10.1 0.0 0.3 60.7 52.4 18.6 68.7 34.2 71.6 3.9 0.0 0.2 45.0 0.8 0.8 0.0 2.4 0.3 18.9 2.6 8.4 40.6 4.8 3.6 0.0 0.1 68.6 0.7 30.8 1.3 0.8 5.8 68.7 96.8 10.1 17.2 28.5 0.7 17.9 0.1 40.3 0.1 89.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 2.3 2.5 2.1 2.1 2.0 4.0 3.2 3.6 3.5 3.7 2.5 3.1 65.3 3.2 1.7 39.8 1.1 41.4 8.4 62.8 35.9 0.3 2.2 2.2 13.0 0.0 16.3 0.0 0.0 0.4 1.2 0.1 1.9 0.1 23.4 10.8 10.5 38.0 0.0 7.6 4.0 0.0 0.5 25.0 0.5 15.0 2.5 0.0 21.0 0.6 45.0 0.0 3.3 0.1 4.1 2.7 28.5 21.0 0.6 13.5 23.2 19.7 3.3 0.0 0.0 1.5 1.0 0.4 0.0 0.0 1.7 10.8 0.0 23.5 16.0 0.2 0.0 7.4 13.2 1.0 3.5 51.4 43.8 1.4 4.6 1.4 0.2 7.2 CERCAM "CEECAM1, GLT25D3" ENSG00000167123 "Cerebral endothelial cell adhesion molecule" Q5T4B2 9 128411751-128437351 "Metabolic proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 551.5" "Cell type enriched" "Detected in many" 7 "Oligodendrocytes: 626.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 280.5;ASC TERT1: 284.1;fHDF/TERT166: 271.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021657, HPA051595" Uncertain Approved "Nucleoplasm,Nucleoli,Cell Junctions" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nucleoli" "Cell Junctions" "HPA021657: AB_1846507, HPA051595: AB_2681545" "unprognostic (2.87e-2)" "unprognostic (1.37e-3)" "unprognostic (1.89e-3)" "unprognostic (2.19e-1)" "unprognostic (4.68e-3)" "unprognostic (7.79e-3)" "unprognostic (3.29e-3)" "unprognostic (5.68e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (1.59e-1)" "unprognostic (5.93e-2)" "prognostic unfavorable (3.33e-16)" "unprognostic (1.34e-2)" "unprognostic (1.04e-1)" "unprognostic (6.05e-3)" "prognostic unfavorable (3.30e-5)" 26.1 8.9 249.9 12.3 411.3 2.5 24.5 248.6 378.3 42.4 140.1 20.9 7.9 35.0 9.7 13.1 23.4 31.2 34.0 261.5 322.7 25.9 3.7 16.9 4.1 344.1 349.4 31.2 30.1 31.0 106.4 49.4 323.9 27.9 7.7 1.0 21.4 22.8 7.0 15.0 12.3 47.4 224.7 10.9 15.8 11.1 386.4 2.4 23.4 7.0 3.9 29.9 30.8 551.5 44.7 26.0 35.2 38.2 280.5 284.1 27.4 145.5 149.7 41.2 32.0 10.3 2.4 0.0 58.3 271.9 33.5 33.8 14.7 22.2 13.9 11.7 25.6 2.9 24.1 15.5 89.7 5.4 84.4 171.6 11.7 48.4 10.5 157.7 44.3 3.0 13.0 36.5 51.8 82.3 2.3 55.7 1.8 2.3 25.4 4.7 23.6 7.3 18.4 15.5 4.9 8.5 33.8 43.1 16.7 10.1 34.4 13.7 48.2 103.5 27.3 138.1 23.2 42.2 35.0 0.8 99.7 17.1 21.0 0.1 0.6 0.0 1.8 0.7 0.1 0.1 0.1 2.1 0.7 0.0 0.0 2.3 0.0 0.6 0.0 1.0 0.0 1.3 249.9 411.3 248.6 378.3 261.5 322.7 344.1 349.4 323.9 224.7 386.4 551.5 8.5 6.4 10.3 7.2 3.5 8.9 6.5 7.0 10.8 1.7 8.7 6.9 3.9 0.0 13.6 11.0 0.0 18.4 5.8 0.0 0.0 11.6 2.7 3.1 18.7 7.7 0.0 2.5 2.9 3.4 61.1 82.3 3.6 6.7 8.8 9.8 16.8 0.1 6.2 6.7 3.3 0.0 2.0 0.8 10.4 2.3 24.2 2.9 40.9 3.7 1.3 0.1 17.5 11.6 626.9 4.5 0.0 26.4 17.9 5.0 0.0 0.9 3.9 0.9 6.6 27.8 26.4 8.6 22.2 2.4 4.1 19.6 3.3 5.9 0.0 2.8 CFAP251 "CaM-IP4, MGC33630, WDR66" ENSG00000158023 "Cilia and flagella associated protein 251" Q8TBY9 12 121918592-122003927 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 22.3;testis: 19.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.7;Fibroblasts: 1.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 1.6" "Lineage enriched" "Detected in single" 8 "dendritic cells: 1.6" "Cell line enhanced" "Detected in many" "HBEC3-KT: 31.8;hTCEpi: 30.8;hTERT-HME1: 19.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA039902, HPA040005" Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA039902: AB_10795236, HPA040005: AB_10795160" "unprognostic (4.92e-3)" "unprognostic (9.05e-2)" "unprognostic (7.99e-3)" "prognostic favorable (3.11e-4)" "unprognostic (5.58e-3)" "unprognostic (6.89e-3)" "unprognostic (1.44e-2)" "unprognostic (2.45e-1)" "unprognostic (2.89e-1)" "unprognostic (2.34e-1)" "unprognostic (7.72e-2)" "unprognostic (1.55e-1)" "unprognostic (2.43e-2)" "unprognostic (4.29e-2)" "unprognostic (1.37e-1)" "unprognostic (1.79e-2)" "unprognostic (1.35e-1)" 1.1 0.8 1.6 0.3 2.4 0.1 1.3 1.3 1.7 3.5 13.2 0.2 0.1 1.9 4.7 0.3 22.3 1.2 1.3 2.4 3.9 2.7 1.4 3.0 0.6 5.5 6.6 2.2 1.7 2.9 6.5 0.9 3.6 0.7 0.1 4.6 1.1 1.6 0.3 1.5 0.2 0.6 2.7 1.7 0.4 19.9 4.1 0.5 4.7 0.4 0.9 0.3 1.3 1.6 4.7 0.4 0.4 0.2 0.5 0.5 0.5 0.3 2.5 1.2 3.0 0.3 1.4 0.2 3.7 0.2 0.7 0.9 0.3 31.8 4.4 0.2 0.5 0.2 0.6 0.3 3.7 0.1 8.6 1.8 30.8 2.4 19.9 0.7 1.3 0.5 7.5 0.1 1.9 0.9 0.3 0.6 0.4 0.4 0.2 0.4 0.8 0.0 5.4 0.5 2.5 0.1 0.2 0.1 0.2 0.8 0.9 0.1 1.0 2.5 3.9 0.5 0.5 0.5 0.2 3.8 2.9 0.1 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.1 0.0 1.6 2.4 1.3 1.7 2.4 3.9 5.5 6.6 3.6 2.7 4.1 1.6 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 CHRDL1 "CHL, MGC1, NRLN1" ENSG00000101938 "Chordin like 1" Q9BU40 X 110673856-110795819 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Differentiation, Neurogenesis, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 224.4" "Group enriched" "Detected in many" 4 "Astrocytes: 50.3;Fibroblasts: 83.8;Leydig cells: 41.0;Muller glia cells: 81.6" "Cancer enhanced" "Detected in many" "prostate cancer: 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "ASC diff: 537.8;ASC TERT1: 724.7;hTERT-RPE1: 341.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000226, HPA000250" Approved "Secreted in other tissues" NA NA 610000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA000226: AB_1078522, HPA000250: AB_1078521" "unprognostic (5.13e-2)" "unprognostic (6.31e-2)" "unprognostic (8.50e-3)" "unprognostic (2.48e-3)" "unprognostic (1.99e-2)" "unprognostic (1.72e-2)" "unprognostic (7.26e-3)" "unprognostic (1.42e-2)" "unprognostic (4.89e-2)" "unprognostic (5.54e-2)" "unprognostic (3.43e-2)" "unprognostic (3.56e-1)" "prognostic unfavorable (2.36e-4)" "unprognostic (4.75e-3)" "unprognostic (7.91e-2)" "unprognostic (5.01e-2)" "prognostic unfavorable (2.23e-4)" 188.3 7.3 7.1 26.2 14.5 0.9 69.8 8.3 14.1 38.8 6.5 74.8 10.8 148.2 20.2 58.0 53.5 47.9 22.0 9.4 6.2 15.1 1.8 76.3 24.4 4.4 4.5 7.1 12.5 84.9 6.4 21.9 4.0 141.6 35.5 55.6 23.3 224.4 6.1 17.5 22.1 101.3 4.3 16.0 17.9 6.5 5.8 10.9 37.8 34.9 11.7 28.3 20.0 6.3 0.0 0.1 3.3 0.0 537.8 724.7 0.3 7.6 3.3 18.8 16.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 23.0 0.0 17.6 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 58.7 0.1 1.6 0.0 341.2 0.0 2.0 0.0 0.0 0.1 0.0 1.0 0.3 21.3 0.0 0.0 0.0 0.0 0.1 3.0 0.0 1.7 5.2 0.0 0.0 0.4 1.4 0.0 0.0 0.0 5.8 4.2 60.4 7.8 0.1 0.1 0.0 5.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 7.1 14.5 8.3 14.1 9.4 6.2 4.4 4.5 4.0 4.3 5.8 6.3 8.4 0.0 2.7 50.3 0.1 4.8 0.0 0.0 0.6 1.5 0.3 0.4 2.3 0.0 1.8 1.8 0.0 0.1 0.1 0.0 0.0 0.3 0.3 0.0 1.0 13.8 0.0 0.0 4.2 0.0 0.1 83.8 2.0 0.2 1.3 0.3 2.2 0.1 0.2 0.0 9.3 0.0 0.0 0.0 8.1 1.4 41.0 1.1 8.8 1.0 0.0 81.6 0.0 13.6 0.2 0.0 0.0 9.1 1.4 0.3 0.0 4.1 1.5 2.9 0.0 2.7 11.2 0.2 8.2 0.3 4.4 0.1 1.0 0.0 0.0 0.1 CLSTN2 "CDHR13, CS2, CSTN2, FLJ39113" ENSG00000158258 "Calsyntenin 2" Q9H4D0 3 139935185-140577397 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 18.2;brain: 26.7;ovary: 64.7" "Cell type enriched" "Detected in many" 4 "Excitatory neurons: 552.2" "Cancer enriched" "Detected in many" 7 "breast cancer: 15.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 32.7;SCLC-21H: 14.5;SuSa: 42.7;THP-1: 9.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031342, HPA061800" Approved Uncertain "Vesicles,Cytokinetic bridge" Yes No 130000 "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "Cytokinetic bridge" "HPA031342: AB_10602800, HPA061800: AB_2684615" "unprognostic (7.58e-2)" "unprognostic (2.64e-2)" "unprognostic (8.02e-2)" "unprognostic (1.51e-3)" "unprognostic (5.52e-3)" "unprognostic (8.35e-2)" "unprognostic (1.58e-1)" "unprognostic (1.21e-1)" "unprognostic (5.58e-1)" "unprognostic (6.25e-2)" "unprognostic (2.24e-1)" "unprognostic (1.81e-1)" "unprognostic (1.71e-1)" "unprognostic (2.52e-2)" "unprognostic (3.16e-2)" "unprognostic (7.63e-5)" "unprognostic (7.22e-5)" 18.2 4.8 17.3 0.3 15.3 0.0 8.8 0.0 26.7 4.2 0.0 1.4 0.5 5.1 0.7 1.0 4.7 2.1 6.1 23.4 0.0 4.3 0.8 1.1 2.7 13.3 3.1 64.7 1.6 0.8 0.9 0.9 9.1 5.3 0.8 2.7 1.3 1.1 1.6 2.0 1.3 6.8 0.0 0.1 1.0 0.6 0.0 0.7 2.8 2.2 0.2 1.6 3.2 15.6 0.0 0.0 5.1 0.0 2.2 0.6 0.0 0.7 0.0 0.0 0.0 2.9 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.1 2.5 0.0 0.1 0.0 32.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 2.1 0.0 0.0 0.0 42.7 2.2 9.4 0.0 1.0 0.5 1.4 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 15.3 0.0 26.7 23.4 0.0 13.3 3.1 9.1 0.0 0.0 15.6 2.1 0.0 0.0 18.3 0.0 0.5 0.3 0.0 8.6 1.8 10.9 2.2 8.0 0.0 0.6 3.7 0.0 0.2 0.1 0.0 1.9 0.2 39.8 0.5 8.9 0.8 0.0 0.0 552.2 0.2 0.0 9.1 0.0 0.2 0.0 25.0 2.2 0.0 0.1 0.0 111.5 0.0 0.0 0.3 1.5 31.1 28.0 0.8 0.0 5.6 0.0 0.8 0.0 108.6 29.4 0.0 0.0 0.7 0.0 5.0 0.0 32.3 3.0 3.8 0.0 28.3 13.7 0.8 0.8 0.4 0.0 0.0 0.7 0.5 0.0 0.3 COL13A1 ENSG00000197467 "Collagen type XIII alpha 1 chain" Q5TAT6 10 69801880-69964275 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Osteogenesis" "Developmental protein, Heparin-binding" "Congenital myasthenic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 30.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 10.1;granulocytes: 20.3;Melanocytes: 5.4;Microglial cells: 6.5;NK-cells: 9.2;Smooth muscle cells: 5.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 63.6;BJ hTERT+: 61.6;hTERT-RPE1: 83.7;HUVEC TERT2: 102.2;PC-3: 93.1;TIME: 137.4" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA050392 Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "HPA050392: AB_2681110" "unprognostic (2.79e-2)" "unprognostic (2.82e-3)" "unprognostic (1.38e-1)" "unprognostic (3.86e-1)" "unprognostic (4.67e-4)" "unprognostic (3.13e-1)" "unprognostic (1.69e-1)" "unprognostic (7.43e-2)" "unprognostic (6.16e-3)" "unprognostic (1.22e-1)" "unprognostic (2.60e-1)" "unprognostic (2.53e-2)" "unprognostic (1.36e-5)" "unprognostic (2.66e-1)" "unprognostic (2.32e-1)" "unprognostic (1.52e-2)" "unprognostic (3.93e-2)" 1.2 1.9 1.5 2.6 1.7 0.3 2.0 9.5 3.3 5.7 1.9 4.6 2.9 1.8 30.4 1.9 2.8 2.4 3.4 1.4 1.5 2.0 0.8 10.9 0.9 1.6 1.6 0.9 2.1 0.8 3.7 1.7 1.8 13.6 3.4 0.0 0.7 8.0 0.9 5.2 3.8 2.9 1.6 8.0 6.2 0.7 1.7 0.3 1.5 1.4 0.8 3.8 1.8 1.5 1.5 0.6 22.1 0.0 0.1 4.3 0.1 63.6 61.6 10.9 5.5 0.0 1.4 0.2 10.5 30.1 1.0 2.3 0.0 0.2 18.9 0.0 1.6 0.0 0.0 0.0 2.9 0.0 0.1 9.8 0.1 27.5 9.0 83.7 102.2 0.0 0.0 0.1 10.4 0.4 0.0 0.2 5.3 0.0 93.1 0.1 0.0 10.3 0.4 0.0 2.4 0.0 0.0 0.2 3.4 0.9 0.0 0.2 137.4 0.3 17.1 5.7 45.7 13.4 0.0 0.1 37.2 0.1 51.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 1.5 1.7 9.5 3.3 1.4 1.5 1.6 1.6 1.8 1.6 1.7 1.5 0.9 0.0 0.6 0.3 0.0 3.4 0.3 0.3 0.6 0.2 0.1 2.0 2.1 0.0 0.5 0.0 0.0 0.0 1.2 0.0 0.0 1.3 0.0 0.0 0.2 3.4 0.0 0.0 1.4 0.0 0.0 10.1 0.0 0.1 20.3 1.8 1.1 0.0 0.1 0.0 0.3 0.0 0.0 0.3 2.3 0.0 0.0 0.3 5.4 6.5 0.0 0.1 9.2 0.0 0.3 0.1 0.0 0.4 0.3 0.5 0.9 0.0 0.1 0.0 0.0 1.1 5.6 0.5 0.5 0.2 3.0 0.1 0.6 0.5 0.1 0.1 COL16A1 ENSG00000084636 "Collagen type XVI alpha 1 chain" Q07092 1 31652263-31704319 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 109.0;Oligodendrocyte precursor cells: 62.4;Oligodendrocytes: 122.0;Peritubular cells: 91.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 133.1;ASC TERT1: 102.9;BJ hTERT+: 115.9;fHDF/TERT166: 106.5;HSkMC: 98.7;U-2197: 92.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA027237 Uncertain "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 960000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "HPA027237: AB_10600699" "unprognostic (2.25e-2)" "unprognostic (9.88e-2)" "unprognostic (5.64e-2)" "unprognostic (8.43e-2)" "prognostic unfavorable (8.08e-4)" "unprognostic (1.00e-1)" "unprognostic (3.99e-2)" "unprognostic (2.04e-1)" "unprognostic (4.48e-3)" "unprognostic (1.66e-3)" "unprognostic (1.44e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (4.00e-9)" "unprognostic (9.62e-2)" "unprognostic (6.13e-2)" "unprognostic (4.60e-2)" "unprognostic (2.15e-2)" 33.6 17.3 19.0 14.4 44.7 0.3 41.0 35.9 32.4 169.7 7.6 78.9 14.8 93.6 23.7 22.4 37.4 39.4 33.6 18.9 29.8 11.5 3.2 31.1 8.5 55.5 43.2 177.9 7.8 3.5 28.6 21.1 48.6 102.8 10.9 8.8 35.5 91.3 8.4 69.3 35.8 56.2 34.0 9.9 42.1 40.9 40.3 5.6 46.8 7.4 4.1 106.9 86.8 57.5 0.1 2.0 0.0 0.1 133.1 102.9 14.6 60.5 115.9 15.1 16.1 0.4 11.0 0.0 1.9 106.5 2.3 48.3 0.0 65.8 3.5 0.0 0.2 0.0 8.1 21.3 45.1 0.0 0.3 98.7 44.6 43.2 22.7 3.8 0.1 0.3 0.0 0.2 2.1 0.0 0.1 0.5 0.1 0.4 0.2 0.2 1.3 0.4 0.0 0.4 1.5 2.7 7.3 1.2 9.6 0.5 1.2 0.0 0.2 52.3 52.5 92.1 1.3 0.1 0.2 0.0 36.1 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 44.7 35.9 32.4 18.9 29.8 55.5 43.2 48.6 34.0 40.3 57.5 4.3 9.6 3.9 109.0 0.1 30.7 14.8 37.5 15.9 2.4 7.9 21.3 8.4 0.0 9.8 18.4 2.1 1.9 0.6 2.0 0.0 4.6 13.6 2.6 11.5 2.8 27.6 0.4 23.9 0.7 3.8 54.3 8.2 2.4 7.0 0.2 5.0 0.0 1.3 0.0 8.2 30.9 8.2 0.6 11.4 26.8 43.8 0.7 14.2 10.3 0.0 31.3 0.0 62.4 122.0 1.2 4.7 91.4 0.3 9.3 16.8 2.1 15.0 2.5 0.0 5.4 25.0 14.9 3.8 1.9 21.2 2.2 2.2 0.5 6.8 15.3 COL4A4 CA44 ENSG00000081052 "Collagen type IV alpha 4 chain" P53420 2 227002714-227164453 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Collecting duct cells: 46.0;Cone photoreceptor cells: 56.3;Granulosa cells: 62.6;Muller glia cells: 78.6;Oligodendrocyte precursor cells: 55.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 4.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "memory B-cell: 4.1" "Lineage enriched" "Detected in single" 5 "B-cells: 4.1" "Cell line enhanced" "Detected in some" "HeLa: 34.3;hTERT-RPE1: 27.2;Karpas-707: 8.9;RPTEC TERT1: 14.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (7.31e-2)" "unprognostic (7.56e-2)" "unprognostic (6.65e-2)" "unprognostic (4.88e-5)" "unprognostic (1.12e-1)" "unprognostic (2.92e-2)" "unprognostic (8.50e-3)" "unprognostic (5.14e-2)" "unprognostic (1.44e-1)" "unprognostic (1.69e-2)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "prognostic favorable (2.30e-13)" "unprognostic (1.53e-2)" "unprognostic (2.65e-1)" "unprognostic (1.30e-1)" "unprognostic (4.15e-2)" 1.0 6.9 1.3 2.1 1.1 0.1 0.7 0.9 0.9 0.5 14.2 0.9 0.9 2.0 7.2 1.1 2.1 4.4 9.2 1.0 1.3 14.0 1.6 8.3 2.8 3.1 2.2 2.0 5.5 0.6 10.2 0.3 2.6 4.5 0.8 8.4 0.7 8.3 6.9 0.3 2.4 1.6 1.5 1.9 1.2 1.3 4.4 0.9 9.9 5.7 4.5 2.9 0.9 1.3 0.0 0.8 0.0 0.0 0.1 0.2 0.0 0.3 0.2 0.1 0.6 0.0 0.7 0.0 1.7 0.0 0.7 0.1 3.1 1.1 0.2 0.0 3.4 0.0 34.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 27.2 0.0 1.1 0.0 8.9 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.9 14.5 5.6 0.8 0.0 2.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 2.7 0.0 0.3 6.7 5.3 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.3 0.0 0.0 4.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.3 1.1 0.9 0.9 1.0 1.3 3.1 2.2 2.6 1.5 4.4 1.3 2.0 73.7 24.1 3.6 11.1 0.5 0.4 0.2 0.0 29.1 0.5 1.3 3.5 8.6 6.2 46.0 56.3 0.0 1.4 0.1 1.9 0.3 0.8 0.3 1.8 5.2 1.2 0.0 2.5 3.8 0.0 8.1 1.5 0.9 0.0 62.6 2.5 0.7 0.1 0.0 10.4 0.1 2.0 0.3 1.5 4.3 25.1 0.8 0.0 12.2 0.0 78.6 0.0 55.3 3.4 4.1 0.1 27.1 14.9 0.2 0.0 3.6 0.0 8.5 0.0 16.8 8.6 0.1 0.6 0.2 0.0 0.0 1.4 0.9 0.3 0.1 COL5A2 ENSG00000204262 "Collagen type V alpha 2 chain" P05997 2 189031898-189225312 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 186.0;Excitatory neurons: 185.2;Fibroblasts: 145.7;Skeletal myocytes: 76.4;Smooth muscle cells: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 447.8;BJ hTERT+ SV40 Large T+ RasG12V: 382.4;fHDF/TERT166: 430.3;HSkMC: 340.2;SuSa: 373.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 820000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (7.45e-2)" "unprognostic (6.44e-3)" "unprognostic (1.22e-1)" "unprognostic (9.31e-2)" "unprognostic (2.01e-1)" "unprognostic (1.13e-1)" "unprognostic (6.28e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (5.97e-2)" "unprognostic (1.78e-2)" "unprognostic (4.44e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.53e-10)" "unprognostic (4.57e-3)" "unprognostic (3.76e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (3.58e-4)" 61.0 4.8 2.3 42.5 5.7 0.2 25.7 0.0 15.6 83.4 3.1 48.7 10.0 43.4 32.7 23.6 21.2 81.9 19.5 17.6 0.8 6.3 12.4 26.1 9.3 2.0 17.4 25.2 7.1 7.5 7.3 111.5 3.8 14.8 25.4 1.6 7.4 12.8 7.8 12.9 22.8 98.3 1.9 10.0 21.5 6.8 1.0 4.7 9.8 26.8 10.3 57.3 29.7 2.5 0.4 93.5 143.9 67.5 212.0 285.3 0.8 213.7 242.3 447.8 382.4 63.2 0.7 0.2 2.2 430.3 23.2 1.6 4.1 2.3 153.3 0.9 1.3 1.0 2.1 0.6 282.6 0.6 0.4 340.2 7.8 129.8 45.3 92.2 108.5 0.9 0.5 0.4 109.1 2.4 0.3 0.3 20.9 0.9 124.3 0.5 33.9 0.4 0.5 24.9 2.0 1.4 5.2 2.5 5.2 373.0 2.1 0.2 91.6 212.8 22.9 52.6 44.6 0.8 0.4 0.6 32.2 0.1 235.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 5.7 0.0 15.6 17.6 0.8 2.0 17.4 3.8 1.9 1.0 2.5 36.7 0.0 1.5 29.7 0.3 26.1 0.2 7.2 6.2 1.3 1.6 3.7 2.8 0.0 0.7 1.8 0.0 4.6 0.2 0.5 1.9 0.6 0.7 22.4 186.0 9.1 38.7 0.0 185.2 0.7 3.9 145.7 0.5 5.1 0.0 4.2 25.7 7.4 6.6 0.0 23.8 0.2 4.1 0.3 27.4 1.7 48.7 1.4 21.4 25.3 0.6 0.7 0.0 21.6 10.9 1.1 0.1 19.5 0.4 0.3 0.1 1.0 1.9 0.8 46.0 76.4 116.0 3.9 1.8 2.0 18.8 6.2 2.8 27.4 0.0 0.4 COL6A3 ENSG00000163359 "Collagen type VI alpha 3 chain" P12111 2 237324003-237414207 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Congenital muscular dystrophy, Disease variant, Dystonia, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 391.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 355.2;Fibroblasts: 567.9;Leydig cells: 315.1;Smooth muscle cells: 197.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 3311.7;ASC TERT1: 4227.5;BJ hTERT+: 1279.6;HSkMC: 2705.3" "Region enhanced" "Detected in some" "basal ganglia: 4.5" "Region enriched" "Detected in many" 4 "spinal cord: 12.0" "HPA010007, HPA010080" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 1000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA010007: , HPA010080: AB_1078550" "unprognostic (8.94e-2)" "unprognostic (7.24e-2)" "unprognostic (6.60e-2)" "unprognostic (3.82e-1)" "unprognostic (3.90e-2)" "unprognostic (2.37e-1)" "unprognostic (5.34e-2)" "unprognostic (2.87e-2)" "unprognostic (8.20e-3)" "unprognostic (2.55e-2)" "unprognostic (1.33e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (5.57e-11)" "unprognostic (1.54e-2)" "unprognostic (2.50e-2)" "unprognostic (3.51e-2)" "unprognostic (1.84e-3)" 150.8 8.3 0.1 126.5 1.0 0.4 74.5 0.2 3.0 212.6 5.2 94.8 22.9 156.3 10.2 44.1 91.8 236.4 61.2 2.4 0.1 5.7 10.3 65.8 30.7 0.6 0.1 123.8 21.1 17.3 2.8 132.9 0.7 47.7 51.7 0.0 45.2 55.4 32.5 35.7 46.6 391.3 0.8 19.0 41.5 15.6 1.8 24.8 38.1 62.3 16.1 188.4 62.7 0.9 0.2 0.5 0.6 0.0 3311.7 4227.5 60.9 815.6 1279.6 167.0 188.2 0.0 0.1 4.5 0.1 818.7 67.4 0.6 0.7 0.9 98.8 2.0 0.1 0.0 0.0 0.0 669.9 0.0 0.4 2705.3 0.0 596.3 1.8 7.8 0.2 0.0 0.1 0.6 6.2 0.0 0.1 0.2 0.5 0.0 7.4 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.4 17.3 0.0 0.4 2.9 19.0 45.1 27.6 142.4 1.0 0.0 0.1 859.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.2 3.0 2.4 0.1 0.6 0.1 0.7 0.8 1.8 0.9 48.2 0.0 10.5 0.3 0.6 61.1 0.5 0.5 1.8 1.0 2.5 2.9 10.6 1.5 3.8 0.0 0.0 4.5 1.2 0.0 0.0 0.9 5.4 11.0 355.2 17.6 0.0 0.0 0.8 0.0 6.2 567.9 6.6 8.7 1.3 1.8 25.4 1.8 8.1 0.0 0.4 0.0 0.0 1.3 85.4 9.6 315.1 5.5 72.9 29.0 2.2 1.1 1.0 0.0 0.3 2.4 0.0 103.4 2.0 0.9 0.0 0.2 1.0 2.3 32.9 19.2 197.7 1.5 1.3 3.3 61.5 5.7 9.3 48.7 0.0 1.0 COL8A2 "FECD, FECD1, PPCD, PPCD2" ENSG00000171812 "Collagen type VIII alpha 2 chain" P25067 1 36095239-36125222 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 10.2;Cardiomyocytes: 13.5;Fibroblasts: 13.4;Macrophages: 6.8;Melanocytes: 7.2;Microglial cells: 8.4;Sertoli cells: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 5.8;fHDF/TERT166: 4.3;HHSteC: 14.1;hTERT-RPE1: 18.2;THP-1: 4.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "spinal cord: 3.6" HPA049788 Uncertain Uncertain "Golgi apparatus" "Secreted to extracellular matrix" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA049788: AB_2680882" "unprognostic (9.98e-2)" "unprognostic (3.26e-2)" "unprognostic (2.51e-2)" "unprognostic (8.41e-3)" "unprognostic (8.76e-2)" "prognostic favorable (9.44e-4)" "unprognostic (1.15e-1)" "unprognostic (1.75e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (7.26e-4)" "unprognostic (3.50e-2)" "unprognostic (3.01e-1)" "prognostic unfavorable (9.35e-5)" "unprognostic (1.08e-2)" "unprognostic (6.77e-2)" "unprognostic (2.24e-2)" "unprognostic (1.16e-3)" 5.2 1.2 2.5 4.4 2.2 0.5 5.6 6.1 2.4 9.0 18.3 5.9 1.4 5.7 1.6 5.8 4.2 4.8 5.4 2.3 2.9 1.1 0.6 4.6 3.1 9.0 4.2 3.3 0.8 0.7 4.0 12.8 7.1 6.1 2.0 0.4 7.4 11.4 0.6 5.5 2.4 3.7 6.1 8.5 9.1 0.9 4.2 4.9 7.5 2.1 3.5 13.3 5.9 5.7 0.0 0.0 0.0 0.0 0.5 1.0 0.1 5.8 1.7 1.6 0.9 0.2 0.1 0.0 0.8 4.3 0.0 0.3 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.1 14.1 0.0 0.0 1.7 0.1 0.7 0.0 18.2 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.4 0.1 0.1 0.0 0.5 0.5 0.5 0.0 0.2 0.4 0.0 4.7 0.1 2.3 0.3 0.4 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.5 2.2 6.1 2.4 2.3 2.9 9.0 4.2 7.1 6.1 4.2 5.7 0.6 0.0 1.8 0.3 0.0 2.2 2.2 1.8 0.0 0.1 1.3 10.2 13.5 0.0 0.7 0.0 0.0 0.4 1.4 0.0 0.0 0.4 0.1 0.2 0.2 0.7 0.0 0.0 0.2 0.2 0.3 13.4 0.5 0.3 2.5 0.5 1.1 0.0 6.2 0.0 0.4 0.0 0.0 2.0 2.7 0.2 3.1 6.8 7.2 8.4 1.2 0.3 0.0 0.5 0.1 0.6 0.0 6.0 0.1 5.3 0.0 0.0 0.2 0.2 6.6 0.7 1.4 0.0 0.3 0.1 1.3 0.8 1.2 0.3 0.0 0.4 CPEB1 "CPEB, FLJ13203" ENSG00000214575 "Cytoplasmic polyadenylation element binding protein 1" Q9BZB8 15 82543201-82648861 "Predicted intracellular proteins" "mRNA processing, Translation regulation" "Activator, Repressor, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.6;testis: 32.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 70.0;Inhibitory neurons: 44.3;Oligodendrocytes: 196.5;Spermatocytes: 34.1;Spermatogonia: 62.3" "Cancer enriched" "Detected in some" 6 "testis cancer: 14.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SK-MEL-30: 37.9;U-2197: 106.0;U-87 MG: 39.1" HPA040396 Supported Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA040396: AB_2676960" "unprognostic (3.97e-2)" "unprognostic (1.01e-1)" "unprognostic (1.44e-2)" "unprognostic (1.77e-3)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "unprognostic (3.90e-2)" "unprognostic (2.07e-2)" "unprognostic (1.35e-2)" "unprognostic (7.51e-3)" "unprognostic (1.97e-3)" "unprognostic (9.50e-3)" "unprognostic (8.17e-2)" "unprognostic (2.05e-2)" "unprognostic (5.37e-4)" 2.8 5.0 10.4 1.3 18.6 0.2 2.5 20.3 18.6 9.3 4.5 6.8 1.2 4.2 7.9 3.6 8.3 4.0 2.9 12.7 17.0 1.2 0.2 1.6 0.5 21.3 21.7 14.3 1.3 0.8 21.8 0.3 24.0 2.3 2.4 4.5 1.5 3.7 2.4 1.9 2.5 3.4 15.0 0.6 2.5 32.4 20.4 0.4 2.3 10.5 0.5 7.7 6.1 33.6 0.1 3.6 0.3 0.4 2.6 0.2 0.1 2.8 0.3 1.8 1.4 0.2 0.1 0.0 6.3 1.1 19.5 0.1 5.1 0.0 0.4 0.0 4.2 0.1 0.1 0.1 1.8 0.1 2.3 1.4 0.0 3.5 0.0 0.2 0.0 7.6 8.9 0.2 1.3 0.2 0.6 0.1 8.2 0.1 1.0 0.0 0.2 0.1 0.0 0.1 10.5 2.4 9.2 0.5 37.9 11.2 0.1 1.1 0.1 18.9 7.5 106.0 6.0 5.3 14.3 1.4 39.1 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.5 0.0 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.1 10.4 18.6 20.3 18.6 12.7 17.0 21.3 21.7 24.0 15.0 20.4 33.6 0.3 0.0 0.0 19.6 0.1 0.8 0.3 0.0 0.0 11.5 0.6 0.3 1.9 0.0 0.0 0.0 10.4 0.0 0.1 0.1 0.0 0.1 12.6 0.5 1.4 0.2 0.0 0.0 70.0 0.0 0.0 5.9 0.5 0.1 1.3 0.3 0.4 0.0 0.3 11.8 44.3 0.0 0.0 0.0 0.8 20.0 4.1 0.4 5.4 10.3 0.1 5.2 0.0 10.1 196.5 0.1 0.0 2.2 0.2 0.5 0.0 0.4 2.2 4.3 6.6 1.9 1.8 34.1 62.3 0.0 0.6 0.1 0.4 0.0 0.0 0.1 CPXM2 "CPX2, UNQ676" ENSG00000121898 "Carboxypeptidase X, M14 family member 2" Q8N436 10 123706207-123940267 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 81.3;intestine: 75.4" "Cell type enhanced" "Detected in many" "Early spermatids: 106.8;Late spermatids: 202.5;Oligodendrocytes: 35.6;Peritubular cells: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "BJ: 18.4;fHDF/TERT166: 71.8;SuSa: 28.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048375 Uncertain "Secreted - unknown location" NA NA 62000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA048375: AB_2680377" "unprognostic (1.50e-1)" "unprognostic (3.66e-1)" "unprognostic (2.58e-2)" "unprognostic (4.02e-3)" "unprognostic (2.69e-2)" "unprognostic (6.48e-2)" "unprognostic (1.32e-2)" "unprognostic (1.32e-2)" "unprognostic (1.26e-1)" "unprognostic (8.57e-2)" "unprognostic (4.42e-2)" "unprognostic (2.14e-1)" "prognostic favorable (9.02e-4)" "unprognostic (3.48e-2)" "unprognostic (2.54e-2)" "unprognostic (1.27e-1)" "unprognostic (1.16e-3)" 29.1 6.4 3.9 5.9 7.2 0.0 20.8 9.2 2.6 5.8 81.3 75.4 6.2 10.2 59.8 18.4 16.0 11.2 18.0 3.5 7.2 11.2 2.4 7.0 2.7 16.1 10.7 16.7 5.2 2.5 10.9 1.2 11.6 15.1 7.0 0.5 9.3 12.7 3.8 7.3 14.9 56.9 20.0 16.8 19.9 9.6 10.4 7.8 15.0 7.9 6.6 28.3 9.2 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.4 0.7 1.1 0.1 0.0 0.0 0.0 0.0 71.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 28.0 0.5 0.0 0.0 0.1 0.1 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 7.2 9.2 2.6 3.5 7.2 16.1 10.7 11.6 20.0 10.4 18.3 22.3 0.0 0.6 0.3 0.1 2.2 0.0 0.2 6.2 0.0 0.3 0.4 2.4 0.0 0.0 1.8 0.0 8.3 0.1 0.2 1.9 0.4 106.8 0.2 0.2 26.1 0.0 0.0 5.0 0.2 0.3 23.0 1.1 0.3 0.0 0.1 16.8 0.0 0.3 1.7 0.5 0.7 0.0 0.0 2.7 202.5 10.8 0.6 3.6 0.0 0.0 0.0 0.0 1.0 35.6 0.1 0.1 79.0 1.4 0.0 0.4 0.0 0.0 0.1 0.0 1.6 2.0 1.3 1.9 0.6 2.0 5.1 0.2 0.0 2.7 0.2 CPZ ENSG00000109625 "Carboxypeptidase Z" Q66K79 4 8592660-8619759 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 144.3" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 1.5;Fibroblasts: 8.5;Microglial cells: 2.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 73.6;BJ: 39.7;BJ hTERT+: 51.7;hTERT-RPE1: 30.6;RH-30: 57.6;U-2197: 46.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA078608 Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA078608: " "unprognostic (2.58e-1)" "unprognostic (7.16e-2)" "unprognostic (4.83e-2)" "unprognostic (1.42e-1)" "unprognostic (7.77e-2)" "unprognostic (2.20e-2)" "unprognostic (2.98e-1)" "unprognostic (7.77e-2)" "unprognostic (2.30e-1)" "unprognostic (1.95e-2)" "unprognostic (1.41e-1)" "unprognostic (1.59e-1)" "unprognostic (7.23e-8)" "unprognostic (4.30e-3)" "unprognostic (3.58e-2)" "unprognostic (6.13e-4)" "unprognostic (5.51e-2)" 11.1 1.8 0.3 2.7 1.0 0.0 11.8 0.5 2.9 33.3 2.3 4.6 0.8 14.6 9.1 7.4 19.9 30.7 2.8 0.8 0.4 2.0 1.4 7.1 2.8 0.7 0.5 144.3 3.2 1.8 5.2 42.1 0.8 5.9 1.8 0.1 1.5 24.2 0.2 13.8 2.6 8.4 1.2 1.4 3.3 3.1 0.3 1.5 7.8 0.0 1.0 23.0 25.1 0.9 26.1 0.4 0.0 1.6 5.0 0.5 73.6 39.7 51.7 14.5 5.8 1.7 0.7 0.0 3.7 21.3 0.3 0.0 0.0 0.0 5.4 0.0 2.9 0.0 0.3 0.7 4.4 0.0 0.0 9.2 0.0 0.0 0.0 30.6 0.0 0.0 1.2 0.0 0.9 6.1 0.0 0.1 9.2 0.2 22.0 0.1 57.6 0.0 0.0 1.1 0.1 0.1 1.4 0.5 0.1 8.3 0.3 0.0 0.0 2.0 2.6 46.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.5 2.9 0.8 0.4 0.7 0.5 0.8 1.2 0.3 0.9 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.6 0.0 0.6 8.5 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 CRACD "CRAD, KIAA1211" ENSG00000109265 "Capping protein inhibiting regulator of actin dynamics" Q6ZU35 4 56049073-56328625 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.1;intestine: 19.7;testis: 29.6" "Cell type enriched" "Detected in single" 11 "Cardiomyocytes: 3.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 26.7;SH-SY5Y: 56.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043249, HPA048148" Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA 59000 "Cluster 45: Intestine - Brush border" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "Golgi apparatus" "HPA043249: AB_2678388, HPA048148: AB_2680286" "unprognostic (1.65e-1)" "unprognostic (1.98e-1)" "unprognostic (7.74e-3)" "unprognostic (1.31e-1)" "unprognostic (6.04e-1)" "unprognostic (6.44e-2)" "unprognostic (1.98e-2)" "unprognostic (3.24e-2)" "unprognostic (1.34e-1)" "unprognostic (3.12e-2)" "unprognostic (1.11e-1)" "unprognostic (1.09e-1)" "unprognostic (8.05e-6)" "unprognostic (1.02e-1)" "unprognostic (6.54e-2)" "unprognostic (2.79e-2)" "unprognostic (2.93e-1)" 0.5 2.3 6.6 3.1 9.6 3.9 0.3 8.7 5.6 1.6 0.0 9.5 13.8 3.5 4.2 0.5 2.9 11.3 0.8 5.7 12.8 0.7 0.6 1.0 2.2 18.8 13.3 1.2 1.8 6.3 0.9 0.6 19.1 1.7 8.1 4.1 1.0 3.5 0.0 0.5 19.7 4.4 8.7 2.5 2.7 29.6 11.9 0.6 0.1 0.2 1.9 1.3 1.2 6.2 0.0 2.9 11.2 0.9 0.3 0.0 4.1 0.1 0.4 0.5 1.2 3.4 0.4 10.2 0.3 0.0 9.1 0.0 9.6 0.2 0.3 0.9 5.6 5.7 5.1 0.5 1.6 4.8 0.8 0.4 0.2 0.0 0.1 3.6 5.3 9.1 0.0 9.8 0.1 1.4 7.1 0.4 6.0 8.7 7.2 6.8 6.1 0.2 0.1 2.6 26.7 56.7 1.0 0.3 6.9 9.4 2.4 0.5 2.1 0.3 2.8 0.7 2.6 9.7 6.9 0.1 2.8 0.2 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 9.6 8.7 5.6 5.7 12.8 18.8 13.3 19.1 8.7 11.9 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 CRIM1 S52 ENSG00000150938 "Cysteine rich transmembrane BMP regulator 1" Q9NZV1 2 36355778-36551135 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 163.8" "Cell type enhanced" "Detected in many" "Adipocytes: 262.9;Hepatic stellate cells: 207.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 466.5;fHDF/TERT166: 462.5;TIME: 651.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000556 Enhanced "Intracellular and membrane" NA NA 170000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA000556: AB_1078567" "unprognostic (2.15e-1)" "unprognostic (5.41e-2)" "unprognostic (6.39e-2)" "unprognostic (3.17e-3)" "unprognostic (3.88e-2)" "unprognostic (3.44e-2)" "unprognostic (1.88e-1)" "unprognostic (6.25e-2)" "unprognostic (2.32e-1)" "unprognostic (4.11e-3)" "unprognostic (8.19e-2)" "unprognostic (1.26e-1)" "prognostic favorable (9.51e-4)" "unprognostic (1.98e-2)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" "unprognostic (6.67e-2)" 88.3 14.6 27.0 18.8 28.1 3.5 58.9 9.4 23.5 26.7 51.4 28.7 14.9 26.6 16.7 30.5 34.4 32.2 34.5 20.3 28.8 70.0 16.0 50.1 14.8 23.5 21.9 36.9 23.5 29.2 7.4 163.8 21.2 25.8 23.2 29.5 31.1 32.6 50.1 27.2 18.2 35.7 22.1 47.1 17.5 12.4 36.1 9.9 33.8 36.5 8.7 38.9 22.2 17.1 100.9 75.4 15.2 17.5 69.1 78.0 125.0 466.5 244.7 255.4 133.4 95.3 34.2 0.2 297.9 462.5 166.1 42.8 11.4 75.2 206.5 1.1 8.7 3.2 96.7 55.5 221.5 2.2 0.6 110.1 55.2 102.4 182.4 238.4 361.9 1.9 4.7 0.7 271.6 9.2 0.2 1.2 11.9 5.2 22.1 5.4 19.6 15.5 159.8 41.1 1.8 0.2 81.5 26.4 3.4 56.2 72.3 2.0 651.1 321.7 116.1 40.4 229.1 25.5 0.5 0.9 94.7 0.4 100.8 1.4 0.1 0.5 0.6 0.0 0.4 0.3 0.2 0.3 0.1 0.2 0.0 0.3 0.2 0.4 0.6 2.1 0.2 0.0 27.0 28.1 9.4 23.5 20.3 28.8 23.5 21.9 21.2 22.1 36.1 17.1 262.9 12.8 43.3 100.2 5.4 66.0 38.5 30.1 43.9 12.0 55.6 72.9 34.4 47.1 26.5 132.4 2.1 111.9 27.1 49.5 3.9 33.5 1.0 37.1 27.7 159.8 31.8 10.7 85.1 2.6 40.6 41.0 10.2 75.9 1.3 27.4 207.1 3.6 27.7 0.0 57.5 37.7 36.7 7.7 32.5 2.0 19.0 8.2 39.2 135.9 7.1 18.5 6.2 65.9 17.2 26.5 30.9 19.9 6.9 75.5 11.5 38.4 28.9 42.5 46.0 18.4 164.6 2.1 9.4 22.0 30.1 173.5 17.1 5.7 33.2 58.3 CSGALNACT1 "ChGn, CSGalNAcT-1, FLJ11264" ENSG00000147408 "Chondroitin sulfate N-acetylgalactosaminyltransferase 1" Q8TDX6 8 19404161-19758029 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 86.7" "Cell type enhanced" "Detected in many" "Astrocytes: 494.3;Excitatory neurons: 144.4;Granulosa cells: 214.1;Microglial cells: 224.9;Oligodendrocyte precursor cells: 355.9" "Cancer enhanced" "Detected in all" "prostate cancer: 22.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 62.6" "Group enriched" "Detected in all" 5 "B-cells: 44.5;granulocytes: 24.9;T-cells: 62.6" "Cell line enhanced" "Detected in many" "A549: 57.8;BJ hTERT+: 32.3;GAMG: 22.9;RPTEC TERT1: 39.6;U-2197: 36.8;U-87 MG: 26.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA068462 Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Golgi apparatus" "HPA068462: " "unprognostic (8.90e-2)" "unprognostic (1.57e-2)" "unprognostic (4.66e-2)" "unprognostic (2.58e-1)" "unprognostic (6.03e-2)" "unprognostic (3.17e-3)" "unprognostic (9.78e-2)" "unprognostic (7.76e-2)" "unprognostic (1.20e-1)" "unprognostic (1.60e-2)" "unprognostic (8.22e-2)" "unprognostic (6.82e-2)" "unprognostic (1.22e-2)" "unprognostic (1.89e-1)" "unprognostic (2.38e-2)" "unprognostic (1.46e-3)" "unprognostic (1.02e-2)" 19.4 12.5 20.3 8.8 15.7 11.1 7.4 4.8 18.3 18.0 0.7 4.7 3.5 7.0 5.4 31.2 11.8 16.1 35.8 16.3 11.5 6.0 2.8 11.7 7.6 6.3 11.2 57.0 7.9 11.4 3.0 38.8 7.6 31.8 2.5 2.5 6.8 9.8 5.8 4.8 4.7 12.3 6.7 8.7 6.9 2.8 8.9 11.7 86.7 11.0 8.8 23.4 8.1 10.7 2.1 57.8 0.5 0.0 9.3 2.1 7.9 1.4 32.3 0.3 0.3 3.1 1.0 0.0 0.3 0.0 22.9 0.7 0.0 0.0 0.4 7.5 0.4 0.2 16.2 1.9 4.1 0.0 0.1 0.9 1.6 0.7 0.3 0.4 11.6 0.2 0.0 0.1 0.1 2.6 2.9 0.2 0.3 8.3 1.7 0.3 0.1 0.0 39.6 1.6 0.2 0.3 17.2 6.9 2.4 1.5 0.1 0.4 1.0 1.1 1.3 36.8 0.9 0.3 0.0 0.0 26.0 3.4 11.4 0.1 2.9 24.9 5.6 0.1 0.6 44.5 25.7 8.5 2.8 15.9 44.6 11.6 15.6 8.4 0.4 4.2 62.6 11.7 20.3 15.7 4.8 18.3 16.3 11.5 6.3 11.2 7.6 6.7 8.9 10.7 33.3 3.2 1.1 494.3 27.3 4.5 7.4 0.2 0.6 0.3 4.1 0.8 45.8 0.0 0.9 12.9 10.4 1.9 6.2 0.0 1.9 5.7 6.9 7.5 1.2 38.5 3.0 3.2 144.4 1.7 14.6 20.9 2.0 2.0 0.0 214.1 26.7 0.2 15.8 18.5 76.5 0.0 16.2 27.4 6.5 7.4 5.3 14.1 12.4 224.9 3.5 1.0 6.2 355.9 4.6 3.1 0.0 12.0 21.3 21.8 0.0 0.1 1.5 1.0 6.6 2.1 12.0 0.7 0.1 0.5 3.1 8.3 9.6 77.0 0.1 2.8 CTF1 "CT-1, CT1" ENSG00000150281 "Cardiotrophin 1" Q16619 16 30896614-30903547 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 16.4;Cardiomyocytes: 11.4;Distal tubular cells: 31.3;Muller glia cells: 21.1;Proximal tubular cells: 14.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 13.6;ASC TERT1: 14.7;fHDF/TERT166: 11.9;HHSteC: 13.0;HSkMC: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025853 Uncertain "Secreted to blood" NA NA 11900 "Cluster 6: Non-specific - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "CAB025853: " "unprognostic (1.31e-1)" "unprognostic (9.01e-2)" "unprognostic (6.81e-3)" "unprognostic (1.06e-3)" "prognostic unfavorable (7.22e-5)" "unprognostic (2.12e-2)" "unprognostic (1.73e-1)" "prognostic favorable (9.87e-4)" "unprognostic (4.47e-2)" "unprognostic (1.09e-1)" "unprognostic (6.75e-2)" "unprognostic (2.76e-2)" "unprognostic (1.76e-3)" "unprognostic (5.07e-3)" "unprognostic (2.06e-1)" "unprognostic (2.16e-2)" "unprognostic (1.79e-1)" 6.4 8.1 4.8 1.3 4.7 1.5 6.7 4.1 5.2 14.7 5.3 13.4 0.8 17.3 4.2 5.3 12.1 3.8 16.0 4.5 4.5 10.2 1.2 7.4 1.3 5.3 5.8 18.4 3.6 10.0 5.2 2.0 4.7 12.2 1.0 2.1 5.7 12.7 14.1 2.7 4.6 7.6 5.5 1.7 7.6 3.4 5.0 2.1 8.5 10.9 1.1 14.0 9.6 5.0 2.0 0.3 2.6 5.7 13.6 14.7 4.5 4.3 8.5 4.4 5.6 2.4 0.4 0.1 8.3 11.9 0.4 1.5 0.0 3.0 4.4 0.1 0.2 0.1 0.2 0.9 13.0 0.2 0.8 13.9 3.8 3.3 8.0 4.9 1.2 0.2 3.7 0.4 7.9 0.3 0.3 0.4 0.8 1.2 0.8 1.6 3.9 0.0 0.7 0.9 0.2 1.4 0.0 0.1 0.0 4.0 6.9 0.3 0.9 4.2 5.2 0.2 0.1 0.1 0.1 0.2 3.3 0.5 0.0 0.6 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.0 0.2 0.2 0.1 0.1 0.4 0.1 0.1 0.3 0.0 0.0 4.8 4.7 4.1 5.2 4.5 4.5 5.3 5.8 4.7 5.5 5.0 5.0 0.8 3.2 6.4 2.6 0.8 0.4 16.4 1.8 2.2 0.3 6.2 7.1 11.4 2.8 1.8 7.3 0.0 0.3 1.2 0.0 31.3 1.0 0.6 7.1 2.9 1.1 0.0 0.4 0.3 0.4 0.2 3.9 0.0 2.4 0.0 3.8 0.0 0.4 0.6 0.0 0.6 0.2 0.0 0.6 0.8 0.7 2.1 1.1 0.0 1.0 0.4 21.1 0.0 1.0 0.4 0.4 0.0 2.6 0.6 2.7 0.2 14.4 2.5 0.9 0.0 4.6 3.0 0.8 0.4 1.9 0.3 0.4 0.7 3.9 0.2 7.4 CTSK "CTSO, CTSO2, PKND, PYCD" ENSG00000143387 "Cathepsin K" P43235 1 150794880-150809577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 420.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 372.4;Langerhans cells: 123.6;Leydig cells: 119.0;Melanocytes: 97.8;Peritubular cells: 149.7;Theca cells: 80.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebral cortex: 18.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8" "Lineage enriched" "Detected in single" 4 "monocytes: 1.8" "Group enriched" "Detected in many" 9 "ASC diff: 2284.0;ASC TERT1: 813.2;BJ hTERT+: 1949.1" "Low region specificity" "Detected in all" HPA050346 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA050346: AB_2681101" "unprognostic (1.48e-1)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (7.61e-3)" "unprognostic (5.08e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (6.60e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.49e-1)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.12e-5)" "unprognostic (6.07e-3)" "unprognostic (2.98e-2)" "unprognostic (5.93e-3)" "unprognostic (6.41e-2)" 224.1 12.5 2.7 33.1 2.8 3.1 227.7 2.9 18.1 420.6 16.4 68.6 13.8 334.0 44.9 46.0 74.0 299.2 35.8 2.7 2.6 12.7 9.0 36.4 42.1 2.7 2.7 78.4 10.6 6.1 14.6 18.9 2.6 34.1 61.8 6.9 53.3 38.0 15.7 219.8 63.8 141.6 2.8 20.2 41.7 15.1 2.7 12.3 34.7 46.3 48.7 210.5 176.2 2.9 0.7 0.3 1.4 0.8 2284.0 813.2 1.0 55.2 1949.1 3.3 8.3 0.3 0.3 0.4 0.6 129.8 0.0 0.6 0.3 0.4 1.2 0.4 0.4 1.4 0.5 0.0 11.0 0.2 1.3 156.5 1.7 50.5 0.7 137.6 4.2 0.6 0.4 1.4 1.5 1.4 0.0 3.0 10.2 1.0 0.0 0.2 0.1 0.1 3.2 0.1 0.6 2.9 0.4 0.0 29.3 3.9 1.0 1.5 1.0 0.7 0.5 0.6 0.6 2.3 1.7 3.6 184.1 0.0 9.9 0.0 1.8 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.4 0.6 2.7 2.8 2.9 18.1 2.7 2.6 2.7 2.7 2.6 2.8 2.7 2.9 17.9 3.2 4.6 2.6 1.1 68.8 0.5 1.6 2.2 12.1 3.7 9.5 2.0 1.5 3.9 3.7 4.2 1.3 2.8 1.5 0.0 1.0 0.9 2.5 59.0 10.2 1.2 0.8 5.0 0.2 2.5 372.4 11.2 3.8 0.0 77.5 14.6 0.5 21.4 3.3 7.7 1.6 8.2 4.6 123.6 4.4 119.0 8.7 97.8 7.5 4.9 2.7 3.1 7.1 2.5 1.4 1.4 149.7 0.8 1.0 1.4 0.1 2.2 7.7 13.1 4.5 33.9 1.4 1.0 2.6 59.1 1.0 5.4 80.9 1.0 0.7 CYS1 ENSG00000205795 "Cystin 1" Q717R9 2 10056780-10080944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 124.6;pancreas: 33.6" "Group enriched" "Detected in many" 4 "Cholangiocytes: 32.9;Collecting duct cells: 51.5;Distal tubular cells: 70.5;Muller glia cells: 48.0;Proximal tubular cells: 54.1" "Cancer enhanced" "Detected in many" "renal cancer: 46.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "RPTEC TERT1: 111.5" "Low region specificity" "Detected in all" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (8.48e-2)" "unprognostic (8.00e-2)" "unprognostic (9.17e-2)" "unprognostic (1.63e-1)" "unprognostic (1.00e-2)" "unprognostic (2.80e-1)" "unprognostic (1.56e-1)" "unprognostic (5.71e-2)" "unprognostic (1.94e-2)" "unprognostic (9.53e-2)" "unprognostic (7.05e-2)" "unprognostic (7.03e-2)" "prognostic favorable (1.27e-5)" "unprognostic (2.19e-3)" "unprognostic (1.47e-1)" "unprognostic (8.93e-2)" "unprognostic (1.20e-2)" 3.1 1.6 6.0 1.2 5.7 0.0 1.9 5.3 7.8 8.4 15.5 11.7 2.5 7.8 3.6 3.9 6.3 9.1 6.1 5.5 5.5 124.6 1.0 6.1 1.1 6.9 6.0 12.4 33.6 1.7 7.2 0.1 5.6 4.9 1.8 2.2 2.9 7.2 1.0 1.5 3.4 5.9 6.4 2.9 3.9 1.0 5.2 0.5 5.6 2.1 2.1 3.5 6.6 5.9 0.0 0.3 0.0 0.0 0.5 2.6 0.1 0.4 1.6 0.2 0.1 0.2 0.0 0.0 0.4 4.4 0.9 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 3.7 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 111.5 0.0 0.0 0.5 0.4 0.3 0.0 1.3 2.0 0.2 0.0 6.0 3.2 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 5.7 5.3 7.8 5.5 5.5 6.9 6.0 5.6 6.4 5.2 5.9 0.9 6.4 1.1 1.0 1.0 0.5 0.1 0.6 0.0 10.3 0.5 5.5 7.3 32.9 0.0 51.5 0.0 0.0 0.2 0.0 70.5 7.0 0.1 0.3 0.9 0.6 0.0 0.0 2.9 1.1 0.6 8.8 0.0 4.6 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.3 0.0 3.4 1.0 0.0 2.8 0.0 48.0 0.0 3.0 0.6 0.4 0.0 4.5 0.1 0.3 0.0 54.1 0.0 1.9 0.0 0.5 3.9 0.0 1.4 0.0 0.1 0.0 0.3 0.1 0.0 0.1 DACT3 "DAPPER3, MGC15476, RRR1" ENSG00000197380 "Dishevelled binding antagonist of beta catenin 3" Q96B18 19 46647551-46661182 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 23.9;Oligodendrocytes: 27.2;Smooth muscle cells: 22.9" "Cancer enhanced" "Detected in many" "glioma: 7.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 10.5;SH-SY5Y: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043053 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles Nucleoplasm "HPA043053: AB_10794769" "unprognostic (2.35e-1)" "unprognostic (3.08e-1)" "unprognostic (5.30e-3)" "unprognostic (5.08e-2)" "unprognostic (2.02e-1)" "unprognostic (1.09e-1)" "unprognostic (2.66e-1)" "unprognostic (2.03e-2)" "unprognostic (3.27e-2)" "unprognostic (2.03e-4)" "unprognostic (1.70e-1)" "unprognostic (2.67e-1)" "prognostic unfavorable (7.97e-8)" "unprognostic (1.59e-2)" "unprognostic (4.03e-2)" "unprognostic (3.54e-3)" "prognostic unfavorable (6.66e-4)" 9.1 3.3 42.1 5.9 42.0 1.4 5.4 41.1 54.4 34.7 3.6 53.9 3.9 48.2 14.3 7.4 37.4 7.2 27.5 48.6 33.4 5.9 2.6 14.0 1.1 45.4 40.1 17.0 1.1 1.9 4.1 1.7 39.9 19.7 6.7 5.8 1.7 24.6 2.2 4.1 13.0 31.6 34.7 6.8 18.0 18.7 46.3 0.5 4.8 2.9 0.9 39.0 15.9 58.0 0.2 0.2 5.6 5.3 1.9 1.5 0.5 3.1 5.2 1.0 1.5 0.2 0.3 0.5 2.0 10.5 1.0 0.3 3.6 0.1 1.0 0.3 1.9 1.2 0.8 0.2 2.7 0.1 2.1 4.9 0.1 1.3 0.1 0.6 0.4 0.7 1.8 1.8 0.9 0.4 0.2 1.4 2.2 0.0 0.8 4.6 1.3 0.3 0.2 0.3 2.1 24.6 0.4 0.2 0.4 5.7 0.4 0.5 0.4 2.6 3.2 2.6 0.5 1.6 0.5 0.8 0.5 0.8 1.9 2.6 0.3 0.3 0.2 0.1 0.1 0.3 0.2 0.2 0.1 0.5 0.2 0.2 1.6 0.7 0.2 0.3 0.2 0.1 42.1 42.0 41.1 54.4 48.6 33.4 45.4 40.1 39.9 34.7 46.3 58.0 1.9 6.4 5.5 13.7 0.2 2.3 1.5 0.0 0.0 16.5 1.0 2.4 17.8 1.5 0.7 0.0 2.1 5.4 0.5 0.3 0.0 0.0 23.9 0.4 9.3 3.1 1.8 0.0 9.2 0.0 2.6 7.4 0.0 0.8 6.3 0.5 1.8 0.2 1.1 1.7 16.7 0.2 2.0 1.6 9.2 8.6 7.8 1.4 3.6 7.5 1.2 9.2 2.1 15.1 27.2 0.1 1.2 14.7 0.1 1.0 0.2 0.3 0.2 6.3 6.6 2.3 22.9 2.3 2.5 0.4 3.3 9.9 1.0 4.3 0.2 1.0 DENND2A "FAM31D, KIAA1277" ENSG00000146966 "DENN domain containing 2A" Q9ULE3 7 140518420-140673993 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 114.9;Horizontal cells: 89.2;Oligodendrocyte precursor cells: 72.4;Paneth cells: 69.5" "Cancer enriched" "Detected in all" 6 "glioma: 28.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 57.7;BJ hTERT+: 60.8;PC-3: 29.1;RPTEC TERT1: 72.7;U-2197: 32.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (5.02e-2)" "unprognostic (1.14e-1)" "prognostic favorable (9.35e-4)" "unprognostic (1.78e-1)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.95e-2)" "unprognostic (1.43e-1)" "unprognostic (3.10e-2)" "unprognostic (1.05e-1)" "unprognostic (1.28e-1)" "unprognostic (1.57e-3)" "unprognostic (2.09e-2)" "prognostic unfavorable (3.05e-6)" "unprognostic (1.03e-1)" "unprognostic (2.41e-1)" "unprognostic (3.54e-2)" "unprognostic (2.38e-3)" 15.4 3.9 28.9 2.5 32.5 0.6 11.0 23.5 25.8 25.0 46.9 12.0 3.9 26.2 5.1 9.6 30.7 11.1 16.1 25.2 28.8 14.5 3.1 17.6 2.3 43.7 39.7 21.7 2.2 5.0 26.3 15.5 33.7 11.4 5.6 11.5 2.6 5.4 7.1 3.9 8.9 16.0 34.6 12.2 6.6 2.1 32.1 0.8 3.7 7.8 1.8 12.1 11.4 26.2 0.2 0.9 57.7 0.5 6.2 1.1 12.4 2.2 60.8 9.5 15.3 0.0 0.1 0.1 0.4 0.6 10.2 0.2 11.0 0.8 17.8 0.0 1.0 0.0 0.2 0.0 1.6 0.2 0.1 2.8 0.6 13.9 2.1 24.9 0.0 0.1 0.1 0.2 0.0 0.2 0.1 0.3 12.3 0.1 29.1 2.1 3.7 0.2 72.7 0.1 4.6 14.5 0.0 0.0 0.0 16.7 0.1 0.6 0.0 10.9 2.2 32.1 5.9 0.3 0.0 0.1 0.9 0.1 3.9 1.0 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.1 1.2 0.3 0.1 0.2 0.1 0.0 28.9 32.5 23.5 25.8 25.2 28.8 43.7 39.7 33.7 34.6 32.1 26.2 13.8 0.0 3.0 34.9 0.5 1.3 1.9 0.1 0.6 7.4 1.9 1.0 4.3 0.0 1.3 0.0 8.4 1.0 0.3 114.9 7.9 0.0 1.4 0.4 8.3 4.6 9.6 0.0 10.0 0.0 4.9 14.8 1.1 0.3 11.4 22.4 9.7 0.7 2.4 89.2 23.2 37.1 0.0 0.3 2.1 1.0 18.6 0.6 1.8 32.8 0.1 16.2 0.0 72.4 42.3 0.1 69.5 10.5 0.0 2.2 3.8 0.1 1.0 10.5 13.1 11.8 11.3 0.1 0.9 0.2 0.4 0.4 1.1 0.2 42.7 1.2 DKK3 "REIC, RIG" ENSG00000050165 "Dickkopf WNT signaling pathway inhibitor 3" Q9UBP4 11 11956207-12009769 "Plasma proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1224.0" "Group enriched" "Detected in many" 7 "Cardiomyocytes: 884.3;Muller glia cells: 1960.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 6.2;memory CD8 T-cell: 3.8" "Lineage enriched" "Detected in single" 62 "T-cells: 6.2" "Cell line enhanced" "Detected in many" "BJ: 418.9;BJ hTERT+: 643.0;fHDF/TERT166: 614.4;hTERT-RPE1: 370.2;TIME: 349.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011868, CAB024949" Approved Supported "Nuclear bodies,Vesicles,Cytosol" "Secreted in other tissues" No No 18000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Nuclear bodies, Cytosol" "CAB024949: , HPA011868: AB_1847716" "unprognostic (4.24e-2)" "unprognostic (6.40e-2)" "unprognostic (1.96e-1)" "unprognostic (7.84e-2)" "unprognostic (3.06e-3)" "unprognostic (6.58e-3)" "unprognostic (1.14e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-3)" "unprognostic (5.28e-2)" "unprognostic (4.51e-2)" "unprognostic (3.87e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (7.41e-3)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.02e-3)" 31.2 79.1 110.7 10.0 183.6 0.2 26.0 12.6 135.2 89.7 104.8 53.2 14.6 47.0 16.7 29.7 23.0 67.0 1224.0 147.7 80.2 17.0 5.6 123.7 8.5 95.1 54.3 38.1 18.2 34.2 38.2 25.0 46.8 59.4 13.0 204.1 30.9 78.1 7.8 29.7 24.6 43.1 83.9 33.2 31.7 30.9 99.9 4.7 16.4 18.8 5.4 40.9 48.3 121.6 1.5 13.1 18.1 0.1 15.3 29.7 0.6 418.9 643.0 182.4 205.5 9.6 3.2 0.0 44.8 614.4 96.8 64.4 1.5 181.9 69.5 0.1 0.5 0.0 1.7 0.0 113.6 0.0 0.3 45.3 60.0 61.9 151.3 370.2 195.3 0.0 0.2 0.4 256.4 0.0 0.1 0.4 8.6 0.0 0.5 0.1 1.2 0.1 62.5 0.6 0.5 53.2 2.0 0.0 0.2 47.9 0.2 0.5 349.7 107.5 82.8 11.2 110.3 0.1 0.0 0.3 18.1 0.0 103.5 0.0 0.0 0.0 0.5 0.0 6.2 0.0 0.6 3.8 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 110.7 183.6 12.6 135.2 147.7 80.2 95.1 54.3 46.8 83.9 99.9 121.6 5.8 3.2 3.0 94.3 0.1 45.6 59.5 70.3 93.4 31.6 3.2 103.2 884.3 0.0 12.8 0.0 12.5 0.5 0.4 0.0 0.0 0.8 104.3 0.7 8.4 32.9 1.8 0.0 90.4 0.2 0.8 106.1 7.1 0.6 1.3 17.0 66.8 0.4 20.4 13.5 83.7 0.1 0.0 1.3 12.5 88.5 20.5 1.4 64.0 38.4 0.0 1960.4 0.0 27.6 14.7 1.1 0.1 57.6 1.7 32.8 0.0 0.2 2.9 67.5 190.7 12.7 83.4 1.2 3.2 5.8 14.8 0.8 4.1 0.5 0.3 3.0 DLG3 "KIAA1232, MRX90, NE-Dlg, NEDLG, PPP1R82, SAP-102, SAP102" ENSG00000082458 "Discs large MAGUK scaffold protein 3" Q92796 X 70444835-70505490 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 55.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001733, HPA078130" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 35: T-regs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 12: NES - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Nucleoli" "HPA001733: AB_1078675, HPA078130: AB_2686879" "prognostic unfavorable (1.69e-4)" "unprognostic (1.87e-3)" "unprognostic (1.37e-1)" "unprognostic (2.77e-1)" "unprognostic (4.65e-2)" "unprognostic (3.44e-2)" "unprognostic (3.64e-1)" "unprognostic (1.20e-2)" "unprognostic (7.79e-2)" "unprognostic (7.92e-2)" "unprognostic (1.26e-1)" "unprognostic (5.98e-2)" "prognostic favorable (1.72e-10)" "unprognostic (3.36e-2)" "unprognostic (5.45e-2)" "unprognostic (1.51e-2)" "unprognostic (1.97e-3)" 3.6 3.7 14.6 4.9 16.0 0.6 11.7 8.3 19.2 10.9 9.5 18.6 13.4 8.3 25.5 20.4 19.1 10.7 7.9 19.7 10.1 16.7 1.7 8.8 3.6 6.1 9.5 11.9 35.2 36.3 11.6 5.9 9.0 11.4 18.9 10.5 23.2 10.8 1.2 11.8 16.0 9.0 6.6 20.0 17.3 1.8 10.9 4.6 15.3 2.0 7.4 10.3 12.2 12.9 6.9 3.1 18.9 8.1 4.8 5.8 13.2 4.0 4.5 2.2 2.2 19.4 15.8 0.0 9.1 4.0 1.6 14.5 37.1 8.8 1.4 8.1 11.3 0.0 17.4 10.7 9.4 0.2 2.6 6.1 5.7 2.8 6.1 19.4 0.8 12.9 3.7 26.5 2.1 24.1 15.8 0.1 31.9 55.5 22.3 14.7 9.3 3.0 12.8 20.7 8.9 0.5 3.2 36.9 7.3 15.6 19.4 0.0 1.5 2.5 2.5 2.4 3.0 17.3 13.9 8.4 3.7 0.1 3.7 0.0 0.0 0.0 0.5 0.0 0.5 0.1 0.4 0.7 0.0 0.0 0.3 0.4 0.0 0.5 0.0 0.0 0.7 0.1 14.6 16.0 8.3 19.2 19.7 10.1 6.1 9.5 9.0 6.6 10.9 12.9 2.2 19.2 22.5 4.6 1.7 0.8 5.5 10.8 7.4 20.2 16.8 10.4 17.2 22.8 17.5 9.2 0.0 6.3 7.0 36.7 11.7 15.0 0.0 27.7 5.7 1.8 25.7 0.8 24.8 24.9 2.6 7.4 17.9 15.8 1.3 6.4 3.6 0.3 0.6 5.0 24.5 23.7 4.1 0.3 1.2 0.3 1.5 1.3 1.8 7.5 1.8 11.6 3.1 20.1 5.4 21.6 19.3 6.4 5.7 13.9 26.1 6.0 31.5 6.3 6.6 4.0 11.1 2.9 2.9 13.1 2.0 1.6 8.1 2.5 21.4 10.5 ECRG4 "augurin, C2orf40" ENSG00000119147 "ECRG4 augurin precursor" Q9H1Z8 2 106063246-106078155 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 225.3" "Cell type enhanced" "Detected in some" "Adipocytes: 87.6;Fibroblasts: 25.3;Smooth muscle cells: 19.1" "Cancer enriched" "Detected in many" 11 "thyroid cancer: 72.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 8.5;naive CD8 T-cell: 7.2" "Lineage enriched" "Detected in single" 83 "T-cells: 8.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008546 Uncertain "Secreted to blood" NA NA 330000 "Cluster 32: T-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: Fibroblasts - ECM organization" "HPA008546: AB_2066524" "prognostic favorable (4.58e-4)" "unprognostic (3.91e-1)" "unprognostic (2.44e-2)" "unprognostic (1.34e-2)" "unprognostic (1.09e-1)" "unprognostic (2.32e-1)" "unprognostic (1.61e-3)" "unprognostic (6.56e-3)" "unprognostic (1.82e-2)" "unprognostic (1.25e-1)" "unprognostic (2.35e-3)" "unprognostic (1.36e-2)" "unprognostic (1.06e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (9.11e-3)" "unprognostic (1.30e-4)" 66.7 27.6 5.3 1.1 6.0 0.0 49.6 9.6 5.3 73.8 225.3 47.6 5.3 24.6 28.4 20.2 47.5 9.4 25.7 12.0 13.0 47.1 3.2 27.6 1.7 14.9 21.5 13.2 5.9 0.7 96.2 8.5 15.4 55.1 5.6 0.1 20.4 101.8 10.3 14.1 19.2 9.0 19.4 25.8 165.8 27.0 12.2 2.8 101.1 6.9 0.3 79.6 58.2 11.7 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.1 2.0 1.3 0.0 0.0 8.5 7.2 0.0 0.0 0.0 0.0 0.8 1.4 5.3 6.0 9.6 5.3 12.0 13.0 14.9 21.5 15.4 19.4 12.2 11.7 87.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.0 25.3 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.1 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 EDNRB "ETB, HSCR, HSCR2" ENSG00000136160 "Endothelin receptor type B" P24530 13 77895481-77975529 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Albinism, Deafness, Disease variant, FDA approved drug targets, Hirschsprung disease, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 127.8" "Cell type enhanced" "Detected in many" "Adipocytes: 120.5;Astrocytes: 126.3;Hepatic stellate cells: 112.5;Melanocytes: 110.3;Muller glia cells: 116.2;Sertoli cells: 216.9;Skeletal myocytes: 81.3;Smooth muscle cells: 102.1" "Cancer enhanced" "Detected in all" "melanoma: 127.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 68.0;ASC diff: 50.5;SK-MEL-30: 66.0;U-266/70: 40.7;WM-115: 131.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017842, HPA027546" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Cytosol "CAB017842: , HPA027546: AB_2672327" "unprognostic (7.75e-2)" "unprognostic (6.73e-2)" "unprognostic (1.41e-3)" "unprognostic (2.59e-2)" "unprognostic (8.37e-2)" "unprognostic (2.45e-3)" "unprognostic (4.17e-3)" "unprognostic (5.43e-2)" "unprognostic (1.02e-1)" "unprognostic (1.38e-2)" "unprognostic (3.40e-2)" "unprognostic (3.01e-2)" "prognostic favorable (7.20e-5)" "unprognostic (1.59e-2)" "unprognostic (3.86e-2)" "unprognostic (4.58e-2)" "unprognostic (6.77e-3)" 58.8 41.2 34.7 19.5 50.8 0.9 39.8 44.6 26.1 18.7 6.7 13.0 20.0 13.1 3.7 8.2 14.1 14.9 28.1 27.5 51.6 33.0 50.9 51.2 10.4 76.2 66.0 4.7 11.4 15.3 9.6 127.8 47.9 25.3 13.2 17.9 27.0 6.9 11.3 12.5 21.9 12.9 97.2 16.8 10.6 2.3 64.9 4.0 31.8 18.8 4.7 23.6 15.5 78.7 5.7 0.0 68.0 0.0 50.5 2.0 1.0 0.0 0.1 0.0 0.0 25.9 0.0 0.0 2.6 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.3 0.3 0.0 0.0 3.5 0.0 0.2 13.2 0.0 0.0 0.0 0.1 0.6 0.0 0.2 0.2 1.7 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.1 0.5 0.1 0.0 66.0 8.9 0.0 0.3 0.3 0.6 0.1 0.0 0.4 40.7 24.9 0.1 1.2 0.0 131.8 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 34.7 50.8 44.6 26.1 27.5 51.6 76.2 66.0 47.9 97.2 64.9 78.7 120.5 12.8 51.0 126.3 0.2 14.8 1.0 0.0 1.2 5.8 1.2 2.8 10.8 0.0 2.5 0.0 6.2 14.7 0.3 0.1 0.0 0.0 2.9 2.9 20.7 73.3 0.0 0.0 1.3 0.0 13.9 51.1 1.1 35.9 6.3 2.1 112.5 1.1 13.4 0.0 1.6 0.0 0.0 18.7 10.6 2.2 79.9 5.2 110.3 6.5 0.1 116.2 0.0 48.2 0.9 0.1 0.0 2.6 0.1 2.6 0.0 0.1 1.5 4.4 216.9 81.3 102.1 0.4 2.1 0.2 7.2 5.7 1.6 2.5 0.0 1.5 EMILIN1 "DKFZp586M121, gp115" ENSG00000138080 "Elastin microfibril interfacer 1" Q9Y6C2 2 27078615-27086403 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 64.5;Fibroblasts: 111.3;Hepatic stellate cells: 45.0;Leydig cells: 85.1;Peritubular cells: 167.3;Sertoli cells: 72.3;Smooth muscle cells: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 98.2;BJ hTERT+: 65.0;HHSteC: 99.0;HSkMC: 109.6;SH-SY5Y: 129.4;U-138 MG: 63.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002822 Supported "Secreted to extracellular matrix" NA NA 4300000 "Cluster 49: Eosinophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA002822: AB_1078738" "unprognostic (3.14e-1)" "unprognostic (2.44e-2)" "unprognostic (3.92e-2)" "unprognostic (3.42e-2)" "unprognostic (3.26e-2)" "unprognostic (1.46e-1)" "unprognostic (3.07e-1)" "unprognostic (2.89e-2)" "unprognostic (4.10e-3)" "unprognostic (3.07e-2)" "unprognostic (1.85e-1)" "unprognostic (7.97e-2)" "prognostic unfavorable (8.13e-9)" "unprognostic (8.96e-3)" "unprognostic (3.77e-2)" "unprognostic (1.20e-2)" "unprognostic (5.70e-3)" 55.5 55.7 6.9 47.0 7.1 1.9 43.6 6.4 7.1 139.8 4.6 223.5 24.9 206.3 7.4 23.3 129.2 35.4 68.9 5.9 7.5 55.5 42.4 100.7 11.7 13.0 7.6 172.4 21.2 1.4 26.9 16.2 9.5 96.4 7.9 0.3 17.5 52.1 10.3 19.1 72.0 50.3 8.3 118.1 87.6 16.9 10.4 2.4 29.7 2.6 2.2 142.9 70.2 8.6 0.9 0.7 5.9 0.9 35.8 49.0 1.1 98.2 65.0 20.7 29.7 0.5 0.8 0.6 0.9 56.6 0.1 0.9 0.2 0.2 3.8 3.1 1.3 1.8 0.5 43.9 99.0 1.5 27.0 109.6 0.1 14.2 0.0 0.2 0.2 1.3 1.0 0.9 4.3 1.1 0.9 28.8 3.2 0.5 0.7 15.6 1.3 1.2 0.0 0.4 1.6 129.4 0.3 0.5 1.1 0.4 0.4 2.5 11.9 63.6 2.0 7.6 0.4 1.7 1.8 1.1 0.7 1.3 17.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.2 0.0 6.9 7.1 6.4 7.1 5.9 7.5 13.0 7.6 9.5 8.3 10.4 8.6 5.2 0.0 0.5 6.5 0.4 3.3 0.2 0.0 0.0 0.6 0.8 7.1 2.9 1.5 0.0 0.0 0.0 1.6 0.6 0.2 0.0 0.4 0.6 1.9 64.5 6.3 0.0 4.0 0.2 0.4 1.5 111.3 0.5 1.3 4.5 0.2 45.0 1.0 6.4 0.0 0.3 0.3 0.0 2.5 5.8 10.0 85.1 4.1 10.6 8.4 0.5 3.6 0.0 0.5 0.3 0.8 0.1 167.3 0.8 0.2 0.5 1.0 0.0 1.1 72.3 35.3 52.4 0.6 0.4 0.4 3.1 2.9 1.3 10.7 0.1 0.1 EPHB3 "ETK2, Hek2, Tyro6" ENSG00000182580 "EPH receptor B3" P54753 3 184561785-184582408 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Angiogenesis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 51.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 38.1;Breast myoepithelial cells: 50.8;Enteroendocrine cells: 71.5;Intestinal goblet cells: 43.3;Squamous epithelial cells: 44.3;Undifferentiated cells: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 28.8;HaCaT: 40.2;OE19: 28.3;SK-BR-3: 30.9;T-47d: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA007698, HPA008184, CAB034350" Enhanced NA NA 100000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB034350: AB_2262377, HPA007698: AB_1848205, HPA008184: AB_1848206" "unprognostic (2.94e-2)" "unprognostic (5.88e-2)" "unprognostic (2.17e-2)" "unprognostic (7.80e-2)" "unprognostic (1.52e-1)" "unprognostic (9.19e-2)" "unprognostic (8.35e-2)" "unprognostic (1.94e-1)" "unprognostic (5.51e-2)" "unprognostic (1.76e-1)" "unprognostic (7.42e-2)" "unprognostic (3.31e-1)" "prognostic unfavorable (7.88e-5)" "unprognostic (8.83e-3)" "unprognostic (3.03e-2)" "unprognostic (9.59e-3)" "unprognostic (2.10e-3)" 1.7 0.7 3.0 3.7 2.7 0.1 10.4 5.8 4.1 22.7 1.0 10.3 6.4 10.1 1.8 30.6 4.0 2.8 1.9 2.9 2.4 5.8 0.9 3.4 0.9 5.7 3.4 8.3 14.9 1.1 2.0 5.7 6.1 10.0 10.9 0.5 31.7 3.5 0.5 51.5 6.3 3.8 2.3 1.0 22.8 0.9 4.0 0.7 0.9 0.4 2.4 4.0 20.9 2.7 6.6 2.3 14.8 1.6 4.5 0.3 28.8 1.1 1.9 2.2 1.2 2.0 0.2 0.0 2.8 6.3 1.0 40.2 5.4 1.9 0.6 0.2 1.1 0.0 0.3 0.0 0.3 0.0 0.2 1.2 13.0 1.8 0.2 0.7 0.0 0.0 0.0 0.0 1.0 17.6 0.0 6.4 1.4 28.3 2.5 1.5 9.0 0.0 0.0 5.8 1.9 2.2 1.2 30.9 1.3 7.8 20.5 0.1 0.0 3.6 5.1 1.8 2.5 0.0 0.0 0.1 0.3 0.0 14.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 2.7 5.8 4.1 2.9 2.4 5.7 3.4 6.1 2.3 4.0 2.7 0.9 3.2 2.7 11.1 0.2 24.1 7.6 5.3 17.1 0.9 38.1 50.8 1.8 2.8 4.6 0.0 0.0 10.1 1.1 21.5 1.9 0.5 0.6 3.7 4.0 1.4 71.5 0.0 4.6 1.6 18.7 6.9 27.0 7.5 4.5 2.1 1.8 0.0 23.5 15.2 5.8 43.3 10.2 0.3 9.8 0.4 2.8 2.4 0.0 1.0 0.8 0.1 0.0 5.0 0.3 3.2 7.2 6.0 0.0 6.0 1.7 0.2 1.4 1.0 0.0 4.5 2.9 0.4 0.6 44.3 35.8 16.3 0.8 1.6 55.0 20.7 FAM228B ENSG00000219626 "Family with sequence similarity 228 member B" P0C875 2 24076526-24169640 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 116.9;Late spermatids: 100.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052598, HPA063357" Uncertain Approved "Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Golgi apparatus" "HPA052598: AB_2681880, HPA063357: AB_2684994" "unprognostic (2.48e-1)" "unprognostic (1.98e-1)" "unprognostic (1.15e-2)" "unprognostic (2.66e-1)" "unprognostic (3.81e-1)" "unprognostic (5.05e-2)" "unprognostic (1.85e-2)" "unprognostic (9.14e-2)" "unprognostic (3.32e-1)" "unprognostic (1.32e-1)" "unprognostic (3.39e-5)" "unprognostic (5.62e-2)" "unprognostic (1.02e-2)" "unprognostic (2.07e-2)" "unprognostic (1.70e-1)" "unprognostic (5.15e-1)" "unprognostic (6.93e-2)" 21.8 15.0 44.4 2.9 48.1 7.9 17.1 53.2 63.6 21.1 33.8 20.7 1.7 12.2 19.2 6.8 18.4 9.2 26.0 40.4 47.3 17.0 4.9 11.0 5.5 45.3 43.8 21.4 8.3 14.9 30.6 6.5 45.5 21.6 4.3 8.9 7.5 12.4 13.2 8.2 10.4 7.8 45.6 12.7 11.4 33.4 45.1 6.2 14.0 9.7 5.0 16.9 14.5 54.9 2.6 1.9 3.7 13.9 9.6 12.5 0.4 6.3 5.9 2.3 1.5 0.2 1.6 3.3 3.1 4.8 4.6 0.2 0.9 0.7 2.2 5.0 6.1 4.0 0.6 0.7 18.6 2.0 1.0 11.7 6.5 1.0 9.3 15.5 5.0 3.0 0.4 4.0 3.1 4.1 0.6 9.4 1.2 0.3 5.4 3.2 1.7 1.5 6.8 2.7 1.3 10.0 2.0 0.0 11.3 5.9 3.8 9.3 5.2 4.2 0.4 0.8 2.1 6.7 2.2 3.9 9.2 7.1 2.9 9.4 5.0 10.1 5.2 3.5 2.6 7.4 3.7 4.2 6.0 4.8 5.5 5.7 4.1 4.5 3.3 9.9 3.8 3.1 44.4 48.1 53.2 63.6 40.4 47.3 45.3 43.8 45.5 45.6 45.1 54.9 19.1 51.3 35.3 49.9 10.7 6.4 9.5 8.8 5.2 24.7 11.5 18.7 24.7 10.0 34.9 14.7 8.4 9.7 17.2 1.6 31.3 5.4 116.9 13.2 11.8 17.4 9.6 6.9 52.1 5.5 4.2 20.1 2.6 5.5 25.9 22.3 20.7 3.5 10.4 37.0 52.1 3.2 10.2 12.8 21.7 100.5 42.3 13.2 10.6 39.4 14.7 39.0 21.6 41.7 78.3 3.8 1.1 38.4 4.6 4.3 2.4 12.3 41.9 27.7 52.6 24.3 21.6 39.4 11.4 2.6 7.4 3.3 13.2 17.4 3.1 5.4 FBLN1 FBLN ENSG00000077942 "Fibulin 1" P23142 22 45502238-45601135 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 666.3;Endometrial stromal cells: 628.2;Extravillous trophoblasts: 651.6;Fibroblasts: 1506.5;Syncytiotrophoblasts: 1215.9" "Cancer enhanced" "Detected in all" "endometrial cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 1839.4;ASC TERT1: 809.8;BJ: 1029.3;BJ hTERT+: 1615.9;HSkMC: 1345.8;RT4: 1485.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001612, HPA001613, CAB004393, CAB068187" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 21000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB004393: AB_671972, CAB068187: AB_2665634, HPA001612: AB_1078825, HPA001613: AB_1078824" "unprognostic (6.62e-2)" "unprognostic (2.47e-2)" "unprognostic (1.64e-1)" "prognostic favorable (9.28e-4)" "unprognostic (1.26e-3)" "unprognostic (4.82e-2)" "unprognostic (9.79e-3)" "unprognostic (2.49e-1)" "unprognostic (6.30e-2)" "unprognostic (3.86e-2)" "unprognostic (2.84e-2)" "unprognostic (3.30e-2)" "prognostic unfavorable (3.02e-10)" "unprognostic (1.08e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-2)" "unprognostic (3.64e-2)" 359.3 123.1 17.3 72.3 29.5 1.7 318.2 27.8 27.5 1131.0 802.4 200.7 75.5 410.6 126.0 305.8 497.6 676.1 773.7 47.0 11.9 61.3 15.7 414.9 16.1 21.8 24.5 214.1 106.3 216.9 90.3 505.7 23.1 466.8 83.6 3.1 121.2 158.5 36.0 296.3 174.5 180.3 15.9 24.9 269.1 21.9 24.7 20.5 195.3 47.5 13.0 704.6 940.5 14.6 17.7 41.6 122.9 258.0 1839.4 809.8 559.8 1029.3 1615.9 89.8 33.8 179.2 5.2 0.4 42.8 38.6 2.5 90.9 78.0 2.7 10.8 0.9 21.0 0.4 209.4 121.5 243.2 1.0 1.0 1345.8 15.8 89.6 32.7 1.8 0.2 1.4 0.9 2.1 63.3 2.4 0.8 3.2 173.8 3.7 15.4 1.4 0.9 2.1 41.1 1485.2 8.7 162.7 127.5 589.6 0.6 344.3 3.7 5.4 8.0 17.4 109.3 465.8 1.0 1.6 0.8 1.4 1.2 1.0 43.5 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.5 0.1 0.1 0.1 0.2 0.0 2.4 1.2 0.0 0.1 17.3 29.5 27.8 27.5 47.0 11.9 21.8 24.5 23.1 15.9 24.7 14.6 34.4 6.4 1.3 34.3 1.2 170.9 113.4 54.8 21.1 0.1 5.3 11.6 20.1 10.0 28.3 1.8 0.0 666.3 1.6 0.1 0.0 1.3 10.5 61.5 628.2 34.5 0.0 0.0 0.5 0.2 651.6 1506.5 38.7 256.5 1.3 29.0 22.1 0.6 82.4 0.0 0.8 0.3 6.1 0.0 222.9 25.4 92.2 11.4 170.7 41.2 0.0 0.1 0.0 0.0 0.4 1.0 0.1 30.5 4.5 47.4 0.0 0.3 10.2 0.6 118.3 37.1 81.5 42.2 68.7 23.8 130.3 1215.9 18.2 2.3 0.4 86.9 FBN1 "FBN, MASS, MFS1, OCTD, SGS, WMS" ENSG00000166147 "Fibrillin 1" P35555 15 48408313-48645721 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Heparin-binding, Hormone" "Aortic aneurysm, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 60.9;placenta: 76.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 132.4;Fibroblasts: 388.5;Leydig cells: 236.1;Oligodendrocytes: 218.7;Peritubular cells: 227.2;Skeletal myocytes: 139.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 215.1;ASC TERT1: 460.7;fHDF/TERT166: 420.8;HSkMC: 251.3;hTERT-RPE1: 211.1;U-138 MG: 206.9;U-2197: 305.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002670, HPA017759, HPA021057, CAB058696, CAB068188" Enhanced Approved Cytosol "Secreted to blood" NA NA 520000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "CAB002670: , CAB058696: AB_2665596, CAB068188: AB_2665597, HPA017759: AB_1848584, HPA021057: AB_1848586" "unprognostic (3.97e-2)" "unprognostic (1.55e-2)" "unprognostic (2.40e-2)" "unprognostic (9.50e-2)" "unprognostic (1.51e-1)" "unprognostic (9.49e-2)" "unprognostic (2.00e-2)" "unprognostic (4.79e-2)" "unprognostic (7.82e-2)" "unprognostic (1.50e-2)" "unprognostic (2.78e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (7.44e-5)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.25e-2)" "unprognostic (8.69e-3)" "prognostic unfavorable (5.11e-4)" 60.9 4.4 1.4 14.5 5.4 3.4 13.7 2.8 2.8 36.0 9.5 8.3 3.8 15.2 6.3 12.6 12.2 27.3 23.5 0.8 2.0 2.7 2.9 10.0 3.7 5.2 6.0 28.4 3.3 3.0 2.5 76.7 3.7 8.0 11.7 1.3 4.6 13.2 4.5 5.7 6.6 35.7 2.3 6.4 6.0 7.1 4.7 2.9 18.6 21.2 3.5 18.8 9.9 5.0 0.1 5.2 19.8 22.4 215.1 460.7 0.2 175.8 62.9 51.1 32.4 0.1 0.3 0.1 7.9 420.8 0.4 0.7 3.9 0.6 45.9 20.7 1.2 2.0 88.5 0.2 120.7 0.8 0.3 251.3 0.1 135.9 15.6 211.1 55.5 1.6 0.0 0.4 55.6 0.0 1.5 0.2 4.0 0.2 7.1 0.1 17.0 0.2 5.9 0.5 0.2 12.9 0.0 2.2 0.1 15.3 0.2 1.4 106.8 206.9 6.2 305.8 37.6 1.2 1.0 0.0 138.9 0.3 13.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.4 5.4 2.8 2.8 0.8 2.0 5.2 6.0 3.7 2.3 4.7 5.0 50.0 0.0 1.3 34.9 0.4 25.6 0.8 1.5 0.6 6.1 1.3 3.4 14.2 0.0 5.8 12.9 0.0 132.4 0.4 0.0 0.0 0.2 8.7 4.2 105.2 36.1 0.0 5.5 82.3 0.6 40.8 388.5 3.1 2.0 1.3 22.5 34.6 0.6 15.3 0.0 123.5 0.0 0.0 0.8 39.0 22.8 236.1 5.7 42.7 30.0 2.3 0.8 0.0 76.9 218.7 1.7 0.0 227.2 1.7 0.7 0.1 0.6 3.3 0.2 26.3 139.5 55.8 3.3 3.4 0.8 20.6 65.8 4.3 51.3 0.0 0.2 FBXL2 "FBL2, FBL3" ENSG00000153558 "F-box and leucine rich repeat protein 2" Q9UKC9 3 33277025-33403662 "Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 48.8;Excitatory neurons: 125.0;Inhibitory neurons: 92.8;Late spermatids: 50.7;Oligodendrocyte precursor cells: 55.8;Oligodendrocytes: 49.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 5.7;LHCN-M2: 6.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003240, HPA061783" Approved Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA003240: , HPA061783: AB_2684605" "unprognostic (5.73e-2)" "unprognostic (4.47e-2)" "unprognostic (7.92e-2)" "unprognostic (7.21e-2)" "unprognostic (3.68e-1)" "unprognostic (1.59e-1)" "unprognostic (1.10e-2)" "unprognostic (2.09e-1)" "unprognostic (3.16e-1)" "unprognostic (2.00e-1)" "unprognostic (4.31e-2)" "unprognostic (1.06e-1)" "prognostic favorable (3.35e-4)" "unprognostic (3.30e-3)" "unprognostic (9.72e-2)" "unprognostic (4.28e-2)" "unprognostic (5.90e-2)" 0.9 1.3 3.6 0.4 3.8 0.3 1.0 2.2 4.0 1.1 4.2 1.1 0.7 1.0 2.1 0.4 1.5 0.6 0.9 3.5 3.7 1.4 0.2 1.2 0.3 2.9 2.6 1.4 1.1 2.7 2.7 1.4 3.0 1.0 0.2 4.2 0.8 1.6 0.2 0.6 0.5 0.8 1.6 0.5 0.8 1.1 3.3 0.2 2.3 0.0 0.2 0.8 0.9 2.7 2.7 0.7 1.0 1.0 1.5 2.4 0.4 2.0 1.6 1.8 2.6 0.5 3.1 0.1 0.6 1.3 0.8 0.5 0.9 2.1 1.2 0.2 1.1 0.4 2.3 0.5 1.8 0.2 0.4 0.9 1.6 1.1 0.8 5.7 3.3 1.9 0.5 0.2 6.2 0.2 0.5 0.3 0.7 0.3 0.6 0.1 0.6 0.1 4.6 0.7 1.1 1.1 0.9 0.5 0.8 1.7 1.3 0.7 2.5 0.8 0.7 0.6 1.1 0.2 0.1 0.1 0.8 0.2 0.6 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.0 3.6 3.8 2.2 4.0 3.5 3.7 2.9 2.6 3.0 1.6 3.3 2.7 2.7 3.2 7.3 22.2 1.0 1.1 7.6 5.6 1.8 15.3 3.0 3.7 2.4 2.8 4.8 5.5 25.0 0.5 0.4 0.1 3.9 3.9 48.8 18.8 3.6 3.8 0.0 0.0 125.0 0.4 1.5 5.0 5.6 6.2 0.0 6.2 2.2 0.1 0.5 18.5 92.8 0.3 8.2 0.8 2.4 50.7 1.5 0.5 1.8 22.5 0.1 6.6 0.0 55.8 49.6 4.2 0.1 4.1 0.3 4.2 0.2 3.2 16.5 17.7 6.6 3.6 3.9 21.3 8.6 0.7 1.1 0.7 1.5 3.5 0.1 3.8 FGF13 "FGF2, FHF2, FLJ30672, LINC00889" ENSG00000129682 "Fibroblast growth factor 13" Q92913 X 138614727-139222777 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.0;parathyroid gland: 49.5;skeletal muscle: 67.3;tongue: 52.3" "Cell type enriched" "Detected in many" 6 "Inhibitory neurons: 432.5" "Cancer enhanced" "Detected in some" "prostate cancer: 2.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.7" "Lineage enriched" "Detected in single" 9 "granulocytes: 3.7" "Cell line enhanced" "Detected in many" "AF22: 43.0;fHDF/TERT166: 38.1;HAP1: 39.8;RPMI-8226: 34.4;U-2197: 69.3;WM-115: 37.5" "Low region specificity" "Detected in all" HPA002809 Supported Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA002809: AB_1078855" "unprognostic (3.23e-1)" "unprognostic (3.13e-2)" "unprognostic (5.42e-2)" "unprognostic (1.42e-2)" "unprognostic (1.87e-1)" "unprognostic (2.87e-3)" "unprognostic (9.92e-3)" "unprognostic (2.97e-3)" "unprognostic (4.92e-2)" "unprognostic (5.90e-3)" "unprognostic (5.22e-3)" "unprognostic (6.79e-2)" "unprognostic (4.96e-4)" "unprognostic (4.36e-3)" "unprognostic (1.22e-1)" "unprognostic (2.27e-1)" "unprognostic (7.48e-2)" 18.5 2.6 17.8 2.9 18.9 4.1 6.6 4.0 30.2 11.3 4.9 7.0 4.0 10.7 3.4 6.6 3.6 6.1 1.9 39.4 20.7 7.4 1.8 2.3 5.3 12.4 15.2 8.8 1.1 49.5 4.2 13.3 50.0 17.6 4.8 11.3 11.2 4.9 67.3 1.8 4.7 6.6 11.3 6.2 5.3 4.1 21.9 0.9 5.2 52.3 2.2 6.0 4.3 14.6 0.1 0.5 43.0 0.1 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.2 0.3 0.7 38.1 0.3 2.7 39.8 0.1 0.0 0.3 11.1 0.2 0.3 1.6 1.5 0.3 0.5 0.6 1.0 0.1 0.0 0.2 0.0 2.5 1.8 12.4 4.4 0.3 0.1 0.3 4.4 0.1 14.3 6.6 2.8 34.4 6.3 0.2 0.1 0.2 0.0 0.3 26.8 21.0 0.1 0.2 0.8 1.3 1.8 69.3 19.1 16.2 9.8 0.1 15.3 12.8 37.5 1.6 0.2 0.8 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 3.7 0.1 0.2 0.4 0.1 0.0 17.8 18.9 4.0 30.2 39.4 20.7 12.4 15.2 50.0 11.3 21.9 14.6 9.7 0.0 0.0 12.7 0.1 0.4 3.0 0.3 2.8 3.6 18.3 4.1 2.6 10.0 3.0 7.3 0.0 0.2 0.0 0.5 17.6 4.2 0.0 7.7 5.0 3.6 2.4 0.0 43.5 5.8 0.3 6.1 3.1 20.5 0.0 1.4 1.4 0.1 29.3 0.0 432.5 0.8 6.1 3.7 1.4 1.4 26.1 0.6 1.8 62.8 0.6 44.8 0.0 14.1 2.4 3.8 6.7 24.5 0.1 16.9 0.0 2.9 1.8 4.2 32.9 18.0 13.7 0.0 3.7 0.1 0.9 0.1 0.3 0.8 0.3 1.0 FILIP1L "DOC-1, GIP130" ENSG00000168386 "Filamin A interacting protein 1 like" Q4L180 3 99830141-100114513 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 210.1;Early spermatids: 376.7;Sertoli cells: 256.4;Skeletal myocytes: 184.2;Smooth muscle cells: 351.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.9" "Group enriched" "Detected in many" 4 "dendritic cells: 2.1;monocytes: 2.9" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 84.2;HDLM-2: 79.9;TIME: 145.8" "Region enriched" "Detected in many" 7 "olfactory bulb: 18.0" "Low region specificity" "Detected in all" HPA043133 Approved Approved "Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA043133: AB_10793991" "unprognostic (9.14e-2)" "unprognostic (2.16e-1)" "unprognostic (7.73e-2)" "unprognostic (5.25e-2)" "unprognostic (6.68e-2)" "unprognostic (1.06e-2)" "unprognostic (4.40e-2)" "unprognostic (1.29e-1)" "unprognostic (2.08e-2)" "unprognostic (2.18e-1)" "unprognostic (1.02e-1)" "unprognostic (3.32e-1)" "prognostic unfavorable (9.40e-4)" "unprognostic (2.46e-2)" "unprognostic (9.44e-2)" "unprognostic (5.30e-2)" "unprognostic (1.82e-3)" 77.1 21.7 4.9 52.4 6.3 0.8 32.6 4.8 6.6 63.8 4.0 57.7 28.4 117.6 23.8 56.0 31.2 90.9 54.8 6.2 4.4 24.0 28.1 30.7 30.1 9.6 4.2 76.4 35.5 17.5 3.9 43.9 9.7 67.9 29.8 4.7 9.3 54.3 140.4 16.8 41.2 151.7 3.7 42.9 46.7 22.0 3.6 11.9 20.1 161.5 22.3 101.5 21.9 4.0 59.0 0.0 22.3 0.1 35.8 30.2 2.0 29.4 58.8 50.2 56.5 17.8 0.2 0.2 5.0 84.2 13.2 7.1 0.0 14.4 59.0 79.9 0.6 4.8 0.2 23.3 17.8 1.4 0.0 24.2 5.1 5.6 0.0 32.0 22.8 0.0 3.8 0.5 7.7 0.1 5.2 1.2 1.3 3.1 0.0 0.1 26.1 0.7 33.5 1.0 2.0 3.7 0.4 0.4 0.1 11.7 0.0 10.5 145.8 8.8 0.2 1.9 15.5 4.2 0.2 0.3 6.5 0.4 0.0 0.2 0.4 0.0 0.1 1.0 0.0 0.6 0.1 0.1 2.1 0.6 0.0 0.1 0.2 0.4 2.9 0.4 0.1 0.3 4.9 6.3 4.8 6.6 6.2 4.4 9.6 4.2 9.7 3.7 3.6 4.0 92.9 16.0 23.1 9.4 4.1 27.8 56.7 7.9 2.2 11.8 12.3 6.5 145.7 35.8 2.3 5.5 8.4 1.1 1.8 2.1 1.9 210.1 376.7 2.3 60.5 77.2 3.0 0.0 42.0 109.3 0.7 145.2 21.9 2.4 34.8 16.3 41.0 0.7 3.2 106.0 25.8 5.7 6.1 36.3 98.9 180.2 83.0 86.1 17.8 25.3 17.7 0.9 0.0 22.1 21.6 43.7 0.2 104.2 3.0 5.1 5.4 2.6 1.9 6.0 256.4 184.2 351.9 40.1 2.5 1.5 22.7 3.1 8.8 41.8 3.2 3.5 FMOD SLRR2E ENSG00000122176 Fibromodulin Q06828 1 203340628-203351758 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 26.7;Fibroblasts: 52.5;Intestinal goblet cells: 80.2;Leydig cells: 28.0;Peritubular cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 10.6;CACO-2: 38.6;HHSteC: 11.8;HSkMC: 22.1;OE19: 45.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 71.7" "Secreted to extracellular matrix" NA NA 2600000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 21: OE19 - Mitochondria" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.48e-1)" "unprognostic (8.88e-2)" "unprognostic (9.35e-2)" "unprognostic (2.70e-2)" "unprognostic (1.60e-2)" "unprognostic (4.17e-3)" "unprognostic (1.86e-1)" "unprognostic (3.30e-1)" "unprognostic (5.25e-3)" "unprognostic (1.06e-2)" "unprognostic (1.65e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.40e-5)" "unprognostic (9.40e-3)" "unprognostic (3.58e-2)" "unprognostic (1.27e-3)" "prognostic unfavorable (2.67e-4)" 122.7 13.6 1.3 31.1 2.3 0.1 64.4 1.5 3.9 100.1 9.0 39.4 49.6 105.8 17.2 19.1 85.8 123.6 149.0 1.0 1.5 24.3 11.0 60.2 28.6 2.4 0.9 125.1 33.1 28.0 21.7 81.2 1.5 58.4 62.1 9.9 49.6 49.2 12.6 25.9 21.2 106.5 2.1 18.2 135.6 6.3 1.5 9.6 71.3 25.6 33.8 45.4 60.0 1.4 0.0 0.1 0.0 0.0 10.6 0.7 0.2 7.1 8.1 0.0 1.1 38.6 0.0 0.0 0.8 7.7 0.0 0.3 0.0 0.6 0.5 0.0 0.0 0.0 0.9 0.0 11.8 0.0 0.0 22.1 0.1 0.0 0.4 5.2 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.3 0.0 45.8 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 1.5 0.4 0.0 0.1 1.0 0.3 2.0 0.0 0.3 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.3 1.5 3.9 1.0 1.5 2.4 0.9 1.5 2.1 1.5 1.4 9.3 0.0 6.3 0.0 0.0 6.9 5.0 1.5 6.2 0.2 10.3 26.7 1.6 2.8 2.1 7.3 0.0 1.1 0.4 2.9 0.0 1.9 0.1 1.1 12.1 8.3 6.1 0.0 0.1 0.7 0.7 52.5 12.8 1.6 0.0 0.5 19.2 0.1 1.2 0.0 0.0 80.2 0.0 0.3 9.3 0.4 28.0 0.6 12.4 7.5 0.6 11.9 0.0 0.0 0.0 1.5 2.2 28.6 0.0 11.7 0.7 0.2 0.7 1.0 6.6 1.3 15.5 0.0 0.3 0.6 4.3 3.1 1.2 2.0 8.6 1.6 FNDC1 "bA243O10.1, dJ322A24.1, FNDC2, KIAA1866" ENSG00000164694 "Fibronectin type III domain containing 1" Q4ZHG4 6 159169400-159272108 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 14.2;thyroid gland: 20.3" "Group enriched" "Detected in some" 4 "Fibroblasts: 28.7;Smooth muscle cells: 11.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 32.5" "Group enriched" "Detected in many" 6 "cerebral cortex: 5.4;hippocampal formation: 8.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.0;fHDF/TERT166: 2.9;SuSa: 3.1" "Region enhanced" "Detected in many" "olfactory bulb: 7.0" "Region enhanced" "Detected in many" "spinal cord: 10.3" "HPA030962, HPA030963" Approved Approved "Nuclear speckles" "Secreted to extracellular matrix" NA NA 14000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" "HPA030962: AB_10696212, HPA030963: AB_2673676" "unprognostic (4.59e-2)" "unprognostic (9.17e-3)" "unprognostic (7.62e-2)" "prognostic favorable (6.10e-5)" "unprognostic (4.57e-1)" "unprognostic (2.11e-1)" "unprognostic (5.52e-2)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "unprognostic (1.08e-1)" "unprognostic (4.18e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (1.93e-6)" "unprognostic (6.49e-3)" "unprognostic (1.12e-1)" "unprognostic (3.10e-1)" "unprognostic (1.76e-3)" 5.4 0.5 0.5 1.9 0.3 0.0 2.1 0.1 5.4 6.5 0.2 12.9 2.5 2.2 0.0 1.1 0.6 14.2 3.9 8.7 0.3 0.6 0.7 1.6 2.8 0.1 1.0 1.2 1.1 0.3 0.2 0.9 0.0 0.4 1.8 0.1 0.9 0.8 2.1 0.9 4.2 11.7 0.3 0.5 0.4 0.4 0.4 0.1 20.3 9.6 2.4 1.0 1.6 1.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.0 2.9 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 3.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.1 5.4 8.7 0.3 0.1 1.0 0.0 0.3 0.4 1.2 2.6 0.0 0.6 0.0 0.0 3.2 0.0 0.0 0.0 0.3 0.1 0.5 2.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.3 0.4 4.7 0.7 0.0 0.0 0.2 0.0 0.2 28.7 0.0 0.3 0.0 0.1 1.4 0.0 0.2 0.0 1.7 0.0 0.0 0.0 3.1 0.0 0.3 0.2 1.8 2.8 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 3.0 11.5 1.1 1.4 0.0 1.4 0.1 0.5 0.1 0.0 0.0 FOXF1 "FKHL5, FREAC1" ENSG00000103241 "Forkhead box F1" Q12946 16 86510527-86515422 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 61.2;urinary bladder: 49.9" "Group enriched" "Detected in some" 4 "Endothelial cells: 17.1;Fibroblasts: 46.3;Smooth muscle cells: 18.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BJ: 12.8;BJ hTERT+: 27.9;HHSteC: 26.5;U-2197: 11.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA028886 Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "HPA028886: AB_10601652" "unprognostic (7.91e-2)" "unprognostic (3.02e-3)" "unprognostic (1.23e-1)" "unprognostic (4.38e-2)" "unprognostic (1.84e-2)" "unprognostic (2.62e-3)" "unprognostic (2.37e-2)" "unprognostic (1.08e-1)" "unprognostic (8.22e-2)" "unprognostic (6.07e-3)" "unprognostic (1.06e-1)" "unprognostic (1.91e-2)" "unprognostic (1.29e-2)" "unprognostic (4.89e-2)" "unprognostic (4.20e-2)" "unprognostic (7.11e-2)" "unprognostic (2.44e-1)" 3.6 0.2 6.0 10.2 5.3 0.0 1.2 4.8 5.4 16.2 2.9 61.2 8.9 2.7 1.1 10.1 1.8 15.0 0.8 4.5 4.8 2.1 3.2 34.1 3.2 5.9 5.2 0.7 1.3 1.1 0.4 23.1 6.0 25.8 10.8 0.2 1.2 5.4 0.2 0.3 21.2 11.7 5.1 0.6 26.3 0.7 7.0 0.1 5.4 1.4 1.5 49.9 11.8 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.8 27.9 3.8 1.3 0.0 0.1 0.0 0.0 1.2 2.6 0.0 2.2 0.0 3.3 0.0 1.5 0.0 2.1 0.0 26.5 0.0 2.3 2.8 0.0 4.5 0.5 0.4 4.7 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 4.4 0.8 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.6 0.1 0.0 0.0 0.0 1.9 11.9 0.0 0.0 0.0 0.0 2.5 0.1 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 5.3 4.8 5.4 4.5 4.8 5.9 5.2 6.0 5.1 7.0 5.1 2.0 0.0 0.6 0.0 0.0 0.3 0.3 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.4 0.3 17.1 0.0 0.0 0.0 0.0 0.4 46.3 1.1 0.2 0.0 0.0 2.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.3 0.2 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 1.0 0.0 0.0 0.0 0.4 0.0 0.1 18.7 0.0 1.3 0.6 0.3 1.2 0.1 0.1 0.0 0.6 FRAS1 "FLJ14927, FLJ22031, KIAA1500" ENSG00000138759 "Fraser extracellular matrix complex subunit 1" Q86XX4 4 78057323-78544269 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.8;thyroid gland: 12.0" "Group enriched" "Detected in many" 9 "Excitatory neurons: 204.9;Inhibitory neurons: 377.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 35.9;Hep G2: 21.9;RH-30: 20.1;SiHa: 21.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051601 Approved "Intracellular and membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA051601: AB_2681547" "unprognostic (1.33e-2)" "unprognostic (1.04e-2)" "unprognostic (9.37e-2)" "unprognostic (8.91e-2)" "unprognostic (2.97e-1)" "unprognostic (2.04e-1)" "unprognostic (1.45e-3)" "unprognostic (2.02e-2)" "unprognostic (1.07e-1)" "unprognostic (2.69e-2)" "unprognostic (2.09e-2)" "unprognostic (4.02e-2)" "prognostic favorable (4.69e-4)" "unprognostic (2.56e-1)" "unprognostic (1.10e-1)" "unprognostic (4.78e-3)" "unprognostic (6.09e-2)" 2.0 0.6 3.4 0.5 5.8 0.0 0.7 0.0 7.9 2.1 4.0 3.5 0.3 2.0 1.9 1.7 1.0 0.9 1.5 3.5 3.3 7.4 0.3 3.4 0.1 3.1 3.3 0.2 5.4 0.6 2.4 5.8 3.0 2.3 1.3 2.2 1.0 0.7 2.7 1.3 1.0 1.4 0.6 0.7 0.9 0.6 13.8 2.6 12.0 2.2 0.2 0.5 1.4 4.9 4.6 6.9 2.7 0.0 7.0 2.9 4.8 1.1 4.1 0.6 0.4 5.4 9.8 0.0 8.2 35.9 0.0 1.3 3.8 2.1 0.1 0.0 3.8 4.2 8.5 21.9 0.8 0.0 0.0 14.1 2.3 0.0 5.2 5.4 0.1 0.3 0.0 0.0 4.1 0.2 0.1 0.0 8.6 3.6 1.3 0.0 20.1 0.0 8.7 9.9 5.0 9.7 21.6 6.7 1.3 12.3 0.0 0.0 0.0 0.0 4.5 2.9 1.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 5.8 0.0 7.9 3.5 3.3 3.1 3.3 3.0 0.6 13.8 4.9 0.5 32.1 0.0 9.1 0.1 1.9 2.2 2.5 10.2 10.8 0.8 1.8 7.3 22.8 9.2 29.5 0.0 28.0 0.0 0.8 3.9 7.6 2.1 5.5 1.0 2.0 1.2 0.0 204.9 1.7 1.4 5.3 4.1 13.5 0.0 0.1 1.1 0.2 4.4 0.0 377.7 1.0 0.0 0.0 0.7 2.8 0.6 0.4 1.8 20.6 0.0 0.6 0.0 10.1 5.5 2.7 2.5 0.0 0.0 1.8 1.4 4.3 2.5 2.7 0.0 1.5 3.4 0.8 1.2 10.4 1.3 15.6 0.1 2.8 2.4 0.4 FREM1 "C9orf143, C9orf145, C9orf154, DKFZp686M16108, FLJ25461, TILRR" ENSG00000164946 "FRAS1 related extracellular matrix 1" Q5H8C1 9 14737152-14910995 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Developmental protein" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 36.4" "Group enriched" "Detected in many" 7 "Early spermatids: 73.7;Inhibitory neurons: 126.1;Late spermatids: 144.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "HEL: 163.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA 58000 "Cluster 68: Epididymis - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.13e-5)" "unprognostic (2.59e-3)" "unprognostic (2.89e-1)" "unprognostic (1.13e-1)" "unprognostic (1.97e-1)" "unprognostic (6.27e-3)" "unprognostic (2.50e-1)" "unprognostic (4.66e-3)" "unprognostic (4.43e-1)" "unprognostic (1.31e-1)" "unprognostic (3.62e-2)" "unprognostic (6.23e-2)" "unprognostic (8.95e-13)" "unprognostic (2.28e-3)" "unprognostic (8.53e-2)" "unprognostic (3.41e-2)" "unprognostic (2.86e-1)" 5.3 2.5 0.9 0.8 1.1 0.2 4.8 4.2 1.3 5.0 2.0 6.4 2.1 19.7 36.4 1.0 4.1 3.7 6.4 1.1 1.3 17.0 0.9 2.4 0.0 2.0 1.3 1.4 6.6 5.0 1.0 5.5 1.2 1.1 1.7 1.3 0.8 3.4 0.9 3.3 5.4 14.2 3.0 0.4 1.0 4.2 1.2 1.2 0.7 0.8 0.5 2.1 2.3 3.8 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 163.8 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.4 3.7 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 4.2 1.3 1.1 1.3 2.0 1.3 1.2 3.0 1.2 3.8 0.4 0.0 0.6 13.1 0.3 1.3 0.2 0.0 0.6 2.0 0.1 0.1 2.9 2.8 0.0 1.8 0.0 0.5 0.0 0.2 0.0 0.3 73.7 1.5 7.7 0.4 0.0 3.0 16.2 0.0 0.3 11.2 0.5 1.3 5.1 0.2 3.9 0.0 0.5 0.0 126.1 2.4 0.0 0.6 1.2 144.7 0.6 0.1 0.0 6.5 0.6 4.0 0.0 7.1 4.3 0.2 0.0 1.5 0.0 0.1 13.0 1.3 0.0 0.1 0.0 0.6 2.8 0.8 0.9 0.0 1.1 0.3 0.1 6.1 4.7 0.1 FZD7 FzE3 ENSG00000155760 "Frizzled class receptor 7" O75084 2 202033855-202038441 "G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 30.9;Breast myoepithelial cells: 37.0;Cardiomyocytes: 21.1;Fibroblasts: 23.5;Proximal enterocytes: 21.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 30.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 42.8;BJ hTERT+: 48.4;CAPAN-2: 62.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059979, HPA069165, HPA076183" Approved Supported Vesicles NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 35: Glandular cells - Unknown function" Vesicles "HPA059979: , HPA069165: AB_2686096, HPA076183: " "unprognostic (3.44e-2)" "unprognostic (6.89e-2)" "unprognostic (9.30e-3)" "unprognostic (2.44e-3)" "unprognostic (4.92e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (7.71e-5)" "unprognostic (1.40e-1)" "unprognostic (4.92e-2)" "unprognostic (8.22e-2)" "unprognostic (2.73e-2)" "unprognostic (1.10e-1)" "unprognostic (1.87e-3)" "unprognostic (8.16e-3)" "unprognostic (1.43e-1)" "unprognostic (4.16e-2)" "unprognostic (2.05e-3)" 10.2 3.0 4.9 5.6 4.7 0.4 15.5 30.2 4.3 13.2 6.3 36.7 6.9 18.4 14.1 9.4 16.8 6.3 14.4 8.8 5.0 8.2 1.2 5.3 3.9 5.2 4.9 25.0 1.7 1.1 9.3 5.7 5.5 19.2 5.5 1.3 21.7 23.5 26.7 10.9 10.8 11.1 4.9 1.9 5.9 2.1 4.5 1.1 5.1 9.5 3.8 27.1 15.3 5.6 10.3 5.2 33.2 10.8 10.6 7.9 14.8 42.8 48.4 11.9 13.9 32.2 62.7 0.1 25.1 26.2 7.9 10.6 6.0 1.3 13.7 5.4 8.6 1.1 2.1 2.7 7.2 2.1 2.1 7.6 1.0 6.4 3.7 9.5 0.0 0.7 2.9 2.6 9.8 4.2 0.0 5.7 36.6 2.0 3.5 4.2 6.4 1.1 1.9 6.1 5.5 12.6 5.4 0.4 6.8 26.7 3.8 2.5 0.1 23.8 8.8 15.0 5.4 2.7 2.2 0.1 4.9 0.5 16.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 4.7 30.2 4.3 8.8 5.0 5.2 4.9 5.5 4.9 4.5 5.6 3.5 0.0 8.1 3.6 2.0 10.3 8.3 1.9 14.8 0.0 30.9 37.0 21.1 1.5 0.3 1.8 0.0 0.5 2.0 4.7 1.9 1.6 0.1 1.5 2.0 1.7 1.2 0.0 1.5 0.2 1.1 23.5 2.6 3.6 1.3 7.5 0.7 0.7 1.5 0.0 0.2 9.9 0.0 0.8 5.7 0.5 5.3 2.0 3.6 0.0 0.1 7.5 0.0 0.0 0.1 0.6 2.1 4.9 1.7 6.9 21.3 0.1 0.9 0.6 6.6 13.5 16.3 1.6 2.9 11.4 9.8 0.8 2.5 0.5 7.6 1.8 GAB1 DFNB26 ENSG00000109458 "GRB2 associated binding protein 1" Q13480 4 143336762-143474568 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 114.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 162.7;Microglial cells: 192.0;Oligodendrocyte precursor cells: 288.0;Oligodendrocytes: 1013.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 5.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 74.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034333, HPA066404" Approved Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 14: REH - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoli fibrillar center, Plasma membrane" Cytosol "CAB034333: AB_2107855, HPA066404: " "unprognostic (1.14e-1)" "unprognostic (1.16e-1)" "unprognostic (1.32e-3)" "unprognostic (1.66e-1)" "unprognostic (4.71e-2)" "unprognostic (1.79e-2)" "unprognostic (4.17e-2)" "unprognostic (1.23e-1)" "unprognostic (1.35e-2)" "unprognostic (8.20e-2)" "unprognostic (2.10e-1)" "unprognostic (2.20e-1)" "prognostic favorable (3.91e-5)" "unprognostic (4.99e-2)" "unprognostic (2.70e-1)" "unprognostic (1.68e-1)" "unprognostic (1.91e-1)" 7.9 8.6 23.3 6.7 69.9 11.5 9.9 35.5 30.0 10.6 2.5 19.7 12.1 18.1 14.2 20.4 9.2 12.5 30.5 20.4 34.6 13.9 9.1 17.9 6.1 57.3 45.4 19.5 8.1 11.3 4.3 21.0 47.9 8.5 22.8 6.9 8.9 14.7 13.4 10.7 12.3 17.7 26.4 7.5 11.3 9.2 45.7 5.4 7.5 16.5 8.7 7.1 9.7 114.8 6.7 1.4 16.7 12.1 8.3 7.9 22.0 4.6 15.2 5.4 9.4 12.8 11.2 0.2 1.4 6.5 3.7 3.8 16.2 5.3 6.2 1.0 3.9 12.2 3.7 6.1 5.7 1.6 2.3 9.7 9.5 6.6 4.3 11.5 7.2 0.2 4.1 21.7 3.8 9.7 0.9 0.0 4.8 3.5 5.3 74.6 8.2 8.8 8.4 8.0 3.9 11.8 3.1 13.3 5.6 11.2 8.5 1.6 5.5 6.9 5.4 3.4 3.5 34.6 18.2 26.3 4.7 4.8 5.7 4.1 0.4 0.5 0.0 0.5 0.2 0.9 0.0 0.0 0.5 1.8 0.0 0.0 2.6 5.0 1.7 2.2 0.0 0.3 23.3 69.9 35.5 30.0 20.4 34.6 57.3 45.4 47.9 26.4 45.7 114.8 13.4 28.9 19.0 89.5 13.1 20.3 8.8 3.3 12.0 2.1 11.6 8.9 34.0 8.6 5.3 12.9 0.0 23.5 10.9 26.2 0.0 6.6 0.9 8.8 9.3 16.3 22.2 40.8 162.7 2.6 10.6 14.4 11.2 21.6 2.5 9.6 13.9 7.0 6.1 3.3 62.2 27.8 4.1 11.6 10.2 3.8 20.8 8.8 16.0 192.0 5.6 15.4 1.0 288.0 1013.6 4.9 10.7 18.8 94.4 7.2 9.3 5.4 3.4 0.8 13.1 7.0 14.3 2.0 5.3 19.9 24.9 10.4 2.7 4.4 13.6 13.5 GAL3ST4 FLJ12116 ENSG00000197093 "Galactose-3-O-sulfotransferase 4" Q96RP7 7 100159244-100168617 "Metabolic proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 27.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 37.2;Microglial cells: 23.4;Oligodendrocyte precursor cells: 24.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 4.5;naive CD4 T-cell: 15.0;naive CD8 T-cell: 4.6;plasmacytoid DC: 4.7" "Group enriched" "Detected in many" 29 "dendritic cells: 4.7;T-cells: 15.0" "Cell line enhanced" "Detected in many" "WM-115: 43.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038137, HPA038138" Uncertain Approved Nucleoplasm,Cytosol NA NA 35000 "Cluster 32: T-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm Cytosol "HPA038137: AB_10697239, HPA038138: AB_2675854" "unprognostic (4.22e-2)" "unprognostic (2.97e-2)" "prognostic unfavorable (5.44e-4)" "unprognostic (8.64e-2)" "unprognostic (3.01e-2)" "unprognostic (1.40e-1)" "unprognostic (3.10e-2)" "unprognostic (1.81e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.57e-4)" "unprognostic (2.80e-1)" "unprognostic (2.25e-1)" "prognostic unfavorable (4.14e-4)" "unprognostic (3.98e-2)" "unprognostic (9.67e-2)" "unprognostic (1.89e-2)" "unprognostic (5.36e-2)" 4.3 4.9 9.2 3.9 9.3 0.7 3.7 8.4 12.6 11.0 7.6 6.1 3.8 9.1 3.1 7.8 6.0 5.6 5.0 9.1 9.5 1.4 0.9 5.2 2.9 13.4 9.5 6.3 1.4 3.0 4.2 5.1 10.1 4.8 6.3 0.5 25.6 3.6 1.9 27.7 5.0 9.9 10.7 2.7 2.4 4.8 15.9 22.3 1.9 1.9 3.2 6.7 10.6 13.1 0.1 0.9 5.4 2.3 4.7 9.6 10.9 3.2 3.2 1.8 2.6 0.6 0.2 1.1 0.7 10.4 3.3 12.2 0.3 1.8 0.6 0.1 0.6 0.4 0.2 0.4 3.4 0.3 2.7 11.7 4.6 5.5 0.6 4.0 3.7 4.3 1.6 0.2 3.4 0.4 4.2 0.2 1.9 11.5 1.3 2.7 2.4 0.2 0.0 0.4 0.3 2.2 1.0 0.0 6.7 1.0 0.0 0.3 3.4 0.3 1.6 0.5 0.1 0.2 0.2 2.5 1.9 0.4 43.3 0.0 0.1 0.0 0.5 0.0 0.0 0.1 4.5 0.3 0.0 0.1 15.0 4.6 0.3 0.2 0.1 4.7 1.3 2.2 9.2 9.3 8.4 12.6 9.1 9.5 13.4 9.5 10.1 10.7 15.9 13.1 0.7 0.0 0.5 2.9 0.1 4.2 2.0 3.3 7.4 0.0 2.2 2.4 1.0 1.5 0.9 0.0 0.0 0.3 0.3 1.5 0.0 0.6 0.2 0.2 2.1 1.2 0.0 2.7 0.5 0.0 0.4 7.5 0.0 0.3 0.0 1.2 1.4 0.0 37.2 0.0 0.3 1.3 4.1 1.3 0.8 0.0 4.7 9.6 5.4 23.4 0.7 0.4 0.0 24.6 0.5 0.3 2.5 5.3 0.0 0.5 0.0 0.0 0.1 0.1 0.0 3.7 3.3 0.6 0.3 4.2 8.1 0.8 0.7 0.1 4.1 1.4 GATA5 "bB379O24.1, GATAS" ENSG00000130700 "GATA binding protein 5" Q9BWX5 20 62463497-62475995 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 11.2;testis: 11.5;urinary bladder: 15.4" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 22.4;Hepatic stellate cells: 7.9;Intestinal goblet cells: 8.7;Proximal enterocytes: 38.8" "Cancer enhanced" "Detected in many" "stomach cancer: 5.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.4;HEL: 2.9;K-562: 4.6;SiHa: 2.0;T-47d: 4.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA067583 Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Intestine - Brush border" "Cluster 1: K-562 - Erythropoiesis" "Cluster 45: Enterocytes - Digestion" Nucleoplasm Cytosol "HPA067583: AB_2685867" "unprognostic (2.21e-1)" "unprognostic (2.28e-1)" "unprognostic (1.79e-1)" "unprognostic (2.10e-2)" "unprognostic (2.66e-1)" "unprognostic (2.39e-1)" "unprognostic (2.62e-1)" "unprognostic (8.34e-2)" "unprognostic (1.69e-2)" "unprognostic (5.70e-2)" "unprognostic (1.27e-2)" "unprognostic (7.96e-3)" "unprognostic (2.00e-2)" "unprognostic (1.04e-1)" "unprognostic (2.36e-2)" "unprognostic (5.39e-3)" 2.4 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.2 0.2 11.2 3.5 0.3 0.1 9.5 1.4 2.8 0.0 0.0 4.0 0.7 1.9 0.0 0.0 0.0 0.7 0.1 3.4 0.4 0.4 0.0 5.4 0.0 0.0 0.3 0.3 0.0 0.2 10.0 0.7 0.0 0.0 10.9 11.5 0.0 0.0 0.6 0.2 0.0 15.4 1.6 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.4 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.2 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 2.0 0.0 0.0 0.8 4.6 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.2 1.7 22.4 0.2 0.0 0.0 7.9 0.0 0.3 0.0 0.0 8.7 0.0 0.0 0.3 2.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.0 0.0 0.0 0.0 38.8 0.0 0.0 0.0 0.0 0.0 0.4 0.5 1.1 0.0 0.1 0.0 0.0 0.0 3.4 0.0 GEM KIR ENSG00000164949 "GTP binding protein overexpressed in skeletal muscle" P55040 8 94249253-94262350 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 229.6" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 721.1;Fibroblasts: 395.9;Langerhans cells: 155.5;Smooth muscle cells: 359.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "myeloid DC: 1.4" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.4" "Cell line enhanced" "Detected in many" "BJ hTERT+: 83.0;U-266/70: 140.6;U-87 MG: 104.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "spinal cord: 24.3" HPA024798 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA024798: AB_10602137" "unprognostic (1.24e-1)" "unprognostic (2.12e-1)" "unprognostic (4.82e-3)" "unprognostic (1.22e-1)" "unprognostic (4.76e-1)" "unprognostic (3.94e-1)" "unprognostic (2.17e-1)" "unprognostic (4.00e-1)" "unprognostic (1.45e-1)" "unprognostic (9.04e-2)" "unprognostic (7.92e-2)" "unprognostic (9.15e-2)" "prognostic unfavorable (1.56e-5)" "unprognostic (1.65e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (4.29e-4)" "unprognostic (2.93e-3)" 56.1 58.4 10.9 35.6 9.6 2.6 36.7 8.3 12.3 57.9 38.7 105.7 16.6 97.2 9.7 59.5 39.0 229.6 63.4 11.0 20.8 32.3 20.2 33.1 23.8 12.7 12.2 19.9 15.7 2.9 27.3 7.3 11.0 31.7 35.9 44.4 13.1 16.8 4.2 10.9 31.1 77.3 8.4 21.9 48.0 3.8 12.2 12.6 23.6 10.8 14.2 90.6 33.6 12.3 1.6 6.1 2.7 0.6 22.9 30.4 0.4 16.1 83.0 21.4 29.8 2.3 4.1 0.0 1.0 6.1 40.1 0.5 2.7 1.4 28.0 12.2 1.4 0.0 0.6 0.0 3.0 0.0 26.3 13.1 0.1 34.1 18.9 24.4 0.9 1.4 0.7 2.7 12.7 0.8 1.0 0.2 4.0 3.4 18.3 0.0 4.9 0.1 7.8 0.0 20.4 12.1 0.0 0.1 2.8 3.4 2.0 0.1 1.2 29.4 8.1 19.2 33.4 140.6 0.9 0.1 104.7 0.1 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 10.9 9.6 8.3 12.3 11.0 20.8 12.7 12.2 11.0 8.4 12.2 12.3 18.4 6.4 25.4 22.2 8.9 68.1 85.7 9.6 721.1 26.8 8.6 35.1 90.8 4.3 4.0 1.8 18.8 0.4 4.1 8.2 0.0 7.3 4.7 26.0 49.2 19.0 25.0 0.0 0.7 0.4 1.4 395.9 54.0 50.3 13.4 1.0 7.1 0.1 2.8 30.3 3.4 2.6 2.0 0.6 155.5 0.3 3.4 43.3 92.5 0.0 0.8 41.9 0.0 0.0 0.3 2.7 17.2 5.7 46.5 20.2 2.1 2.6 1.2 21.4 32.9 55.5 359.5 1.3 1.1 24.1 49.9 3.4 33.4 0.9 4.2 10.6 GLI3 "ACLS, GCPS, PAP-A, PAPA, PAPA1, PAPB, PHS, PPDIV" ENSG00000106571 "GLI family zinc finger 3" P10071 7 41960949-42264100 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 8 "Astrocytes: 301.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 47.1;WM-115: 34.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005534 Approved Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "Nucleoli, Vesicles" "HPA005534: AB_1078973" "unprognostic (2.53e-1)" "unprognostic (2.41e-2)" "unprognostic (7.58e-2)" "unprognostic (8.22e-3)" "unprognostic (1.10e-1)" "unprognostic (1.28e-2)" "unprognostic (1.01e-1)" "unprognostic (5.35e-3)" "unprognostic (2.24e-1)" "unprognostic (7.38e-2)" "unprognostic (4.03e-1)" "unprognostic (3.54e-2)" "unprognostic (1.48e-5)" "unprognostic (9.13e-3)" "unprognostic (5.41e-2)" "unprognostic (3.21e-3)" "unprognostic (7.00e-2)" 6.1 1.9 9.2 3.6 8.8 0.1 8.9 1.0 5.4 7.2 0.0 11.6 1.2 11.8 2.7 3.7 8.2 3.8 1.6 6.3 5.5 1.7 0.3 3.4 0.9 1.7 10.4 13.2 0.7 0.5 1.1 11.9 3.0 5.5 2.9 1.8 2.8 8.2 1.1 8.3 3.4 10.7 0.5 1.1 2.6 1.7 14.4 3.0 4.6 2.3 1.7 4.8 7.3 2.3 0.0 0.0 47.1 0.4 16.9 23.6 3.5 3.1 9.0 9.3 12.8 0.0 0.0 0.0 1.7 22.1 22.7 10.1 8.7 8.9 10.8 0.0 7.0 0.0 6.0 0.0 9.0 0.0 0.1 21.0 12.9 10.6 6.8 5.7 10.6 5.4 0.0 0.2 5.6 5.6 0.4 0.0 20.9 0.0 21.2 12.4 0.1 1.4 0.2 6.4 1.5 0.0 6.3 7.0 4.1 23.8 8.0 0.1 11.3 13.6 18.8 16.0 6.0 0.1 0.0 0.0 7.3 0.2 34.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 8.8 1.0 5.4 6.3 5.5 1.7 10.4 3.0 0.5 14.4 2.3 2.9 0.0 7.7 301.3 0.2 23.5 7.2 8.5 31.9 1.6 20.5 27.1 1.8 0.0 2.3 1.8 0.0 21.1 0.5 0.0 0.0 0.0 16.6 2.4 12.6 3.4 0.0 0.0 0.8 0.0 13.6 25.9 0.0 4.6 1.3 10.5 3.9 0.0 3.3 0.0 3.6 0.1 6.1 0.3 6.3 5.4 19.3 0.4 8.8 22.5 0.0 13.6 0.0 8.5 0.7 0.1 0.0 3.4 1.2 6.6 0.0 3.8 1.5 1.1 13.1 17.0 12.1 0.3 2.2 7.9 15.5 34.2 0.7 5.2 0.1 5.0 GLP2R ENSG00000065325 "Glucagon like peptide 2 receptor" O95838 17 9822206-9892099 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 12.2;intestine: 13.5;urinary bladder: 11.8" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 4.2;Excitatory neurons: 6.4;Leydig cells: 3.1;Rod photoreceptor cells: 23.3" "Cancer enhanced" "Detected in single" "pancreatic cancer: 1.1" "Group enriched" "Detected in many" 6 "basal ganglia: 3.0;cerebral cortex: 3.6;hippocampal formation: 3.2;white matter: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HeLa: 78.1" "Group enriched" "Detected in some" 5 "cerebral cortex: 2.1;hippocampal formation: 2.4" "Low region specificity" "Detected in all" "CAB022690, HPA049244" Supported Supported "Plasma membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "CAB022690: , HPA049244: AB_2680690" "unprognostic (2.14e-1)" "unprognostic (2.45e-3)" "unprognostic (2.66e-3)" "unprognostic (2.21e-2)" "unprognostic (3.81e-3)" "unprognostic (2.09e-1)" "unprognostic (1.39e-2)" "unprognostic (5.15e-2)" "unprognostic (7.63e-2)" "unprognostic (7.14e-2)" "unprognostic (2.19e-1)" "unprognostic (6.16e-3)" "unprognostic (3.40e-8)" "unprognostic (9.53e-5)" "unprognostic (5.51e-2)" "unprognostic (3.92e-1)" "unprognostic (6.48e-3)" 8.1 0.3 0.4 0.7 3.0 0.0 0.8 0.0 3.6 6.0 0.0 13.5 9.9 1.2 0.0 0.7 1.6 12.2 0.6 3.2 0.0 0.3 2.7 1.0 0.6 0.0 0.2 0.4 1.6 0.0 0.0 1.1 0.0 0.1 6.0 3.4 0.0 0.1 0.1 0.1 8.2 1.9 0.0 0.1 3.7 0.4 0.0 0.1 0.2 0.2 0.2 11.8 1.5 1.7 0.0 16.6 0.0 0.0 0.8 0.0 0.8 0.0 0.3 0.0 0.1 0.0 0.5 0.0 0.0 0.0 2.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 78.1 0.6 1.0 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.0 0.0 3.6 3.2 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 6.4 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.4 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.5 0.0 1.5 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 23.3 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GPM6A GPM6 ENSG00000150625 "Glycoprotein M6A" P51674 4 175632934-176002664 "Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "brain: 577.8;choroid plexus: 249.3;retina: 147.3" "Cell type enhanced" "Detected in many" "Astrocytes: 3712.4;Excitatory neurons: 833.0;Inhibitory neurons: 581.3;Muller glia cells: 459.6;Oligodendrocyte precursor cells: 1341.6" "Cancer enriched" "Detected in many" 107 "glioma: 110.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "memory B-cell: 34.8;naive B-cell: 16.6" "Lineage enriched" "Detected in many" 12 "B-cells: 34.8" "Group enriched" "Detected in some" 10 "AF22: 49.9;Daudi: 43.0;HAP1: 17.4;U-251 MG: 50.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017338 Supported NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA017338: AB_1849933" "unprognostic (1.36e-4)" "unprognostic (3.35e-3)" "unprognostic (2.96e-2)" "unprognostic (1.34e-2)" "unprognostic (9.45e-2)" "unprognostic (1.34e-1)" "unprognostic (3.82e-5)" "unprognostic (2.24e-1)" "unprognostic (9.13e-3)" "unprognostic (1.06e-1)" "unprognostic (3.69e-2)" "unprognostic (7.73e-2)" "unprognostic (2.24e-2)" "unprognostic (3.53e-2)" "unprognostic (1.45e-1)" "unprognostic (1.36e-3)" "unprognostic (2.60e-3)" 3.8 4.2 366.9 1.4 455.6 0.5 2.5 422.6 577.8 6.8 249.3 25.4 1.9 7.7 2.9 1.9 7.5 4.4 2.8 469.8 268.7 7.1 13.4 20.1 2.6 225.0 265.4 12.3 1.8 0.7 7.7 0.3 222.4 5.7 6.0 147.3 0.9 6.9 0.6 0.8 3.4 11.1 257.9 15.8 1.1 1.5 281.9 0.3 11.9 0.6 1.3 2.6 2.9 336.4 0.3 0.7 49.9 0.5 0.0 0.0 0.2 0.1 0.5 0.2 0.4 1.1 0.7 43.0 0.2 0.2 1.8 0.9 17.4 1.5 0.1 0.2 4.0 0.5 3.7 1.4 0.1 0.4 0.7 0.1 0.0 0.1 0.2 2.0 0.0 0.1 0.4 1.7 0.0 1.2 1.6 0.6 1.2 0.0 0.6 0.2 0.2 0.3 0.1 2.1 0.5 0.4 0.2 0.9 0.2 0.3 0.6 0.1 0.2 0.9 0.6 0.6 50.8 1.6 0.1 2.6 1.8 0.4 1.1 0.8 0.1 0.1 0.1 0.1 0.1 34.8 0.1 0.0 0.2 16.6 0.1 0.1 0.4 0.1 0.2 2.9 0.1 0.8 366.9 455.6 422.6 577.8 469.8 268.7 225.0 265.4 222.4 257.9 281.9 336.4 0.6 96.1 8.7 3712.4 9.6 1.8 5.3 0.0 0.0 220.3 0.2 0.1 0.7 1.5 0.6 0.0 14.6 0.0 0.0 0.1 1.9 0.0 11.7 0.4 0.1 29.0 0.0 5.3 833.0 0.2 0.2 2.4 0.0 0.2 0.0 0.2 116.0 2.1 0.3 124.5 581.3 0.0 0.0 4.4 0.4 3.6 3.4 1.6 0.0 208.0 0.0 459.6 0.0 1341.6 37.3 0.0 0.0 1.5 0.1 9.0 0.0 3.4 0.0 30.5 0.0 15.3 3.3 0.5 0.4 0.2 0.9 0.1 1.2 3.0 0.0 6.5 GPX8 "EPLA847, UNQ847" ENSG00000164294 "Glutathione peroxidase 8 (putative)" Q8TED1 5 55160167-55167297 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 62.7;Extravillous trophoblasts: 218.9;Fibroblasts: 76.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 254.4;fHDF/TERT166: 246.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036720 Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "Actin filaments" "HPA036720: AB_2675269" "unprognostic (4.85e-2)" "unprognostic (1.23e-2)" "unprognostic (6.53e-2)" "unprognostic (1.92e-2)" "unprognostic (2.31e-2)" "unprognostic (9.74e-3)" "unprognostic (1.78e-2)" "unprognostic (1.63e-3)" "unprognostic (2.07e-2)" "unprognostic (4.34e-2)" "unprognostic (4.31e-2)" "unprognostic (8.68e-2)" "prognostic unfavorable (5.13e-9)" "prognostic unfavorable (7.96e-4)" "unprognostic (8.11e-2)" "unprognostic (1.16e-2)" "unprognostic (2.63e-2)" 13.3 6.1 1.2 12.5 1.2 0.1 12.6 1.2 1.6 37.1 6.9 7.3 2.9 21.1 21.9 6.2 14.3 17.0 11.2 1.0 1.7 6.5 2.2 6.9 3.8 1.5 1.1 27.3 4.6 9.3 2.4 39.7 1.4 10.2 8.4 1.3 7.2 15.8 1.5 5.0 4.1 27.2 1.5 4.0 5.6 5.6 1.2 1.3 22.3 6.3 3.0 17.8 9.8 3.6 37.2 39.0 75.3 77.0 180.7 223.9 36.6 179.8 254.4 97.0 192.7 3.2 82.1 0.0 199.0 246.4 86.5 28.2 46.0 51.5 131.5 0.5 17.3 2.1 49.1 6.9 64.4 0.0 0.0 157.5 60.8 68.3 35.5 126.5 122.7 0.0 1.1 0.1 137.4 14.4 0.0 0.0 32.6 1.0 42.8 0.1 40.2 0.0 65.9 1.3 0.1 1.4 56.6 4.6 68.0 80.8 56.6 3.4 102.7 63.6 65.6 84.5 102.3 0.1 0.5 0.5 103.0 0.1 118.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 1.2 1.2 1.6 1.0 1.7 1.5 1.1 1.4 1.5 1.2 3.6 10.9 0.0 1.1 0.3 0.3 7.1 6.0 38.3 9.1 0.2 8.9 6.1 4.3 0.0 33.3 25.8 0.0 49.5 0.2 0.5 5.9 13.7 0.4 6.5 62.7 18.6 0.0 0.0 0.1 38.8 218.9 76.6 2.6 4.9 4.5 30.9 19.2 0.2 10.2 0.0 0.1 4.7 4.1 0.0 6.9 0.6 51.3 1.1 24.9 5.6 1.1 7.9 0.0 0.0 0.1 15.8 0.3 39.9 1.4 2.6 0.1 0.5 36.5 0.3 13.1 20.1 38.2 0.1 0.4 3.1 6.1 13.3 1.8 29.9 0.9 2.4 GUCY1A1 "GC-SA3, GUC1A3, GUCY1A3" ENSG00000164116 "Guanylate cyclase 1 soluble subunit alpha 1" Q02108 4 155666726-155737059 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 38.4;Alveolar cells type 2: 56.1;Breast glandular cells: 37.4;Breast myoepithelial cells: 24.9;Distal tubular cells: 19.6;Ductal cells: 21.8;Smooth muscle cells: 49.4" "Cancer enhanced" "Detected in all" "prostate cancer: 24.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 8.2;non-classical monocyte: 10.1;plasmacytoid DC: 11.5" "Group enriched" "Detected in many" 35 "dendritic cells: 11.5;monocytes: 10.1;NK-cells: 8.2" "Cell line enhanced" "Detected in some" "HAP1: 6.8;HEK 293: 5.5;Karpas-707: 9.7;MOLT-4: 18.5;RPTEC TERT1: 12.1;RT4: 14.2;SH-SY5Y: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010887, HPA056004, HPA058617" Uncertain Supported Nucleoplasm NA NA 7100 "Cluster 40: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "CAB010887: AB_259901, HPA056004: AB_2683007, HPA058617: AB_2732624" "unprognostic (4.81e-3)" "unprognostic (2.60e-1)" "unprognostic (3.03e-1)" "unprognostic (2.15e-1)" "unprognostic (1.99e-2)" "unprognostic (7.77e-3)" "unprognostic (1.07e-1)" "prognostic favorable (2.38e-4)" "unprognostic (1.85e-3)" "unprognostic (6.46e-2)" "unprognostic (3.42e-2)" "unprognostic (7.16e-2)" "prognostic unfavorable (7.59e-4)" "unprognostic (1.60e-2)" "prognostic unfavorable (3.59e-4)" "unprognostic (2.27e-1)" "unprognostic (6.55e-3)" 14.4 7.8 10.1 17.0 24.1 1.2 15.4 2.8 14.0 14.5 0.1 27.1 8.7 16.1 6.2 7.5 9.5 12.6 33.7 12.7 8.0 15.6 8.0 21.0 8.5 5.3 10.0 5.6 13.1 31.4 3.9 25.9 4.5 25.8 10.3 17.0 5.3 13.9 5.1 2.5 9.2 28.9 8.7 14.1 8.6 1.2 10.2 7.5 7.2 18.7 9.2 7.3 6.6 8.5 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 6.8 0.0 0.0 0.0 5.5 1.3 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 3.6 0.0 9.7 0.0 0.0 18.5 0.0 0.0 0.0 0.2 4.1 0.0 3.0 12.1 14.2 2.5 8.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.2 0.0 2.3 0.1 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.1 8.2 10.1 11.5 0.0 1.0 10.1 24.1 2.8 14.0 12.7 8.0 5.3 10.0 4.5 8.7 10.2 8.5 38.4 9.6 56.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 37.4 24.9 0.0 0.0 6.8 11.0 0.0 0.4 1.7 0.0 19.6 21.8 0.0 5.5 9.7 10.9 0.0 0.0 0.0 2.0 0.3 8.3 0.0 15.2 3.8 3.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 12.9 2.2 0.0 0.0 0.0 49.4 0.0 0.0 0.0 0.0 0.3 0.6 0.1 0.0 0.0 GUCY1B1 "GC-S-beta-1, GC-SB3, GUC1B3, GUCY1B3" ENSG00000061918 "Guanylate cyclase 1 soluble subunit beta 1" Q02153 4 155758992-155807811 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 20.2;Ductal cells: 22.9;Glandular and luminal cells: 15.5;Proximal tubular cells: 22.2;Smooth muscle cells: 36.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "intermediate monocyte: 7.2;non-classical monocyte: 23.9" "Lineage enriched" "Detected in many" 13 "monocytes: 23.9" "Cell line enhanced" "Detected in many" "HEL: 46.0;Karpas-707: 23.7;MOLT-4: 29.9;RPTEC TERT1: 42.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010890, HPA020870" Approved Approved Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "CAB010890: AB_259911, HPA020870: AB_1850444" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (3.55e-2)" "unprognostic (9.10e-3)" "unprognostic (4.69e-2)" "unprognostic (1.41e-2)" "unprognostic (6.88e-2)" "unprognostic (6.69e-3)" "unprognostic (3.03e-3)" "unprognostic (1.47e-1)" "unprognostic (8.37e-2)" "unprognostic (2.84e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (7.35e-3)" "prognostic unfavorable (3.23e-4)" "unprognostic (2.14e-1)" "unprognostic (6.36e-3)" 13.8 7.1 23.6 15.6 30.0 2.2 10.0 5.3 36.6 12.6 0.0 28.9 5.8 16.4 6.0 8.1 13.7 13.3 18.7 30.1 28.2 13.2 7.7 16.5 10.4 9.8 13.9 5.8 10.9 50.3 6.0 43.6 22.8 13.6 8.7 34.7 5.5 12.2 5.9 3.5 11.1 25.0 6.4 11.0 13.8 2.4 14.8 7.2 7.3 14.9 7.3 10.0 11.1 17.0 0.0 0.5 6.5 0.0 2.2 11.4 0.0 2.0 3.6 0.2 0.1 0.0 0.0 0.0 3.0 1.1 5.0 0.1 13.6 0.3 0.8 0.0 4.6 46.0 0.0 0.0 1.2 0.0 0.0 5.1 0.4 0.0 0.2 4.2 0.1 10.2 0.0 23.7 3.0 2.1 29.9 0.1 0.4 0.0 3.2 3.5 0.9 0.7 42.9 4.4 0.7 7.8 0.0 0.2 0.0 6.4 0.0 0.0 0.0 7.3 1.6 12.4 9.5 0.3 0.0 0.0 15.6 0.0 0.0 1.4 0.5 0.5 0.0 7.2 0.0 0.1 0.0 0.0 1.8 0.2 0.0 0.0 0.5 1.3 23.9 1.6 0.0 5.8 23.6 30.0 5.3 36.6 30.1 28.2 9.8 13.9 22.8 6.4 14.8 17.0 20.2 6.4 7.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 2.2 0.0 0.0 0.0 9.2 0.0 1.1 1.1 0.0 5.9 22.9 0.0 3.7 4.3 3.4 0.0 0.0 0.0 4.2 0.2 5.4 0.0 15.5 1.3 4.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.0 22.2 0.0 0.0 0.0 0.0 36.1 0.0 0.0 0.0 0.0 0.7 0.4 0.7 0.0 0.0 HSPB2 "Hs.78846, MKBP" ENSG00000170276 "Heat shock protein family B (small) member 2" Q16082 11 111912734-111914093 "Predicted intracellular proteins" "Stress response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 153.2;skeletal muscle: 251.3;tongue: 316.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 115.7;Fibroblasts: 39.1;Leydig cells: 43.5;Melanocytes: 37.4;Smooth muscle cells: 39.8" "Cancer enhanced" "Detected in many" "melanoma: 5.1;renal cancer: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 48.4;ASC TERT1: 23.4;fHDF/TERT166: 59.7;HSkMC: 23.3;LHCN-M2: 35.2;U-138 MG: 31.5" HPA079414 Approved NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA079414: " "unprognostic (5.46e-2)" "unprognostic (1.46e-1)" "unprognostic (2.30e-1)" "unprognostic (7.69e-3)" "unprognostic (6.82e-2)" "unprognostic (1.51e-2)" "unprognostic (4.37e-2)" "unprognostic (3.25e-1)" "unprognostic (2.04e-1)" "unprognostic (1.67e-2)" "unprognostic (3.55e-2)" "unprognostic (2.19e-1)" "unprognostic (1.36e-1)" "unprognostic (1.69e-3)" "unprognostic (2.63e-1)" "unprognostic (1.99e-1)" "unprognostic (1.46e-2)" 39.8 5.3 26.7 4.3 28.9 0.0 21.5 37.4 32.5 30.2 24.4 21.1 3.4 25.0 5.7 15.4 22.2 18.5 153.2 25.8 26.7 13.3 2.3 17.3 5.4 29.0 27.3 14.0 1.4 1.4 3.8 12.2 27.2 13.1 4.0 1.8 7.1 13.0 251.3 14.7 9.1 19.1 27.2 7.3 9.6 2.3 28.9 1.4 9.6 316.8 2.0 16.1 19.0 26.2 0.0 0.0 0.0 7.0 48.4 23.4 0.2 5.6 0.0 0.0 0.3 0.0 0.0 0.0 0.5 59.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.0 0.0 0.0 23.3 0.0 0.0 0.0 4.2 0.0 0.0 0.2 0.0 35.2 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.2 31.5 3.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.7 28.9 37.4 32.5 25.8 26.7 29.0 27.3 27.2 27.2 28.9 26.2 8.5 0.0 0.0 0.0 0.0 7.0 0.3 0.0 1.2 0.4 5.1 16.4 115.7 1.5 0.6 1.8 0.0 0.8 0.1 0.0 1.9 0.4 0.1 0.1 7.9 3.5 0.0 0.0 0.0 0.0 0.7 39.1 0.0 0.2 0.0 0.4 4.6 0.0 1.4 0.0 0.0 0.0 0.0 0.0 10.3 1.1 43.5 0.6 37.4 0.0 0.0 7.6 0.0 0.0 0.0 0.1 0.0 21.8 0.0 0.3 0.0 23.5 0.0 0.5 13.1 22.8 39.8 0.8 0.6 0.6 5.8 1.5 1.0 0.4 0.0 0.0 IGFBP7 "FSTL2, IGFBP-7, MAC25, PSF" ENSG00000163453 "Insulin like growth factor binding protein 7" Q16270 4 57030773-57110385 "Disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 11440.4;Peritubular cells: 11731.6;Sertoli cells: 8184.6;Smooth muscle cells: 4434.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 21.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 693.6;BJ hTERT+: 643.1;hTERT-RPE1: 1471.3;RPTEC TERT1: 682.7;TIME: 1009.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002196, CAB020668" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 30300000 190000000 "Cluster 52: Eosinophils - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "CAB020668: , HPA002196: AB_1079107" "unprognostic (2.76e-1)" "unprognostic (1.39e-2)" "unprognostic (6.82e-2)" "unprognostic (5.97e-3)" "unprognostic (3.86e-1)" "unprognostic (3.18e-1)" "unprognostic (2.96e-3)" "unprognostic (1.02e-1)" "unprognostic (2.62e-1)" "unprognostic (1.01e-2)" "unprognostic (2.57e-1)" "unprognostic (6.65e-2)" "unprognostic (2.28e-1)" "unprognostic (2.62e-3)" "unprognostic (1.78e-1)" "unprognostic (3.58e-1)" "unprognostic (7.55e-2)" 833.0 374.9 99.4 151.1 124.0 44.2 583.2 112.7 149.7 640.3 1299.1 473.1 105.6 653.2 260.4 115.3 618.1 405.7 1117.2 132.7 143.8 1298.6 283.2 532.4 133.1 185.2 138.7 359.1 270.1 77.2 246.0 66.6 146.4 506.0 83.2 4.7 193.7 659.0 185.6 193.6 259.6 334.9 136.8 436.9 267.4 259.2 187.9 48.9 995.3 91.8 81.9 546.4 494.0 132.6 1.3 4.8 1.1 0.0 134.8 50.4 4.7 693.6 643.1 59.2 19.0 2.8 0.1 0.3 433.7 33.5 35.3 70.2 0.7 111.1 15.7 1.3 5.4 2.5 78.7 0.5 207.7 17.1 17.9 234.7 55.8 96.8 26.2 1471.3 138.2 0.6 0.5 0.9 142.8 0.0 0.5 74.5 5.9 0.0 1.3 13.4 0.4 2.8 682.7 0.0 1.0 1.8 130.2 9.5 0.0 276.3 1.8 64.6 1009.4 60.5 46.4 7.8 114.8 41.1 0.4 1.4 159.2 58.3 1.8 2.0 3.9 21.7 0.1 4.1 0.1 0.0 0.0 0.0 10.7 0.0 0.0 0.1 0.3 10.8 4.5 0.4 0.1 1.7 99.4 124.0 112.7 149.7 132.7 143.8 185.2 138.7 146.4 136.8 187.9 132.6 2254.8 112.2 20.2 164.9 16.2 238.5 127.2 300.5 24.5 5.9 27.7 53.5 148.2 20.0 90.6 2087.4 22.9 6.6 76.9 1.4 516.5 2455.3 75.9 1235.5 702.2 2740.1 1.2 82.7 0.7 15.1 8.3 1435.9 29.0 381.3 15.8 1205.0 3079.4 16.4 26.5 0.0 3.7 1.0 61.1 101.9 375.7 335.4 11440.4 70.4 944.5 151.8 41.8 17.1 345.0 11.6 0.8 84.6 1.5 11731.6 11.0 113.3 0.0 692.2 731.0 12.5 8184.6 155.0 4434.0 36.6 38.6 9.9 179.1 5.7 51.3 759.1 2.5 64.0 IGSF10 "CMF608, FLJ25972" ENSG00000152580 "Immunoglobulin superfamily member 10" Q6WRI0 3 151425384-151458709 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 17.7" "Cell type enhanced" "Detected in many" "Early spermatids: 170.5;Horizontal cells: 60.6;Late spermatids: 34.1;Microglial cells: 61.8;Syncytiotrophoblasts: 30.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HeLa: 44.1;HL-60: 23.3;REH: 17.2;RPMI-8226: 55.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA012655, HPA012921" Uncertain Approved Vesicles "Secreted - unknown location" NA NA 540000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA012655: , HPA012921: AB_1851526" "unprognostic (1.78e-3)" "unprognostic (2.48e-2)" "unprognostic (1.71e-1)" "unprognostic (3.47e-7)" "unprognostic (1.68e-1)" "unprognostic (2.12e-1)" "unprognostic (9.82e-2)" "unprognostic (8.84e-4)" "unprognostic (9.38e-3)" "unprognostic (1.96e-1)" "unprognostic (5.70e-2)" "unprognostic (2.04e-1)" "unprognostic (7.52e-4)" "unprognostic (6.01e-2)" "unprognostic (8.93e-2)" "unprognostic (4.59e-3)" "unprognostic (7.57e-4)" 3.9 4.0 1.4 0.9 0.7 0.6 6.1 0.3 1.0 0.5 3.2 1.3 0.5 1.4 1.6 2.9 4.3 9.7 4.3 2.8 1.1 0.2 0.3 8.6 1.4 0.1 1.0 17.7 0.7 1.3 1.7 0.7 0.3 0.1 1.3 0.2 5.2 0.2 0.1 1.9 1.2 1.5 0.0 0.9 0.7 0.9 3.6 1.3 1.5 0.5 2.5 2.2 0.3 0.3 0.0 0.1 0.3 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.1 0.0 0.4 0.0 0.0 0.3 0.3 7.5 44.1 0.0 1.6 23.3 0.1 0.4 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 17.2 0.1 55.1 0.1 0.1 1.0 0.0 5.9 0.0 0.0 0.2 0.0 0.2 0.0 0.1 1.1 0.0 0.0 2.4 0.0 0.0 0.2 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.7 0.3 1.0 2.8 1.1 0.1 1.0 0.3 0.0 3.6 0.3 2.0 0.0 0.5 1.0 0.6 2.4 1.2 0.5 2.8 15.8 0.6 0.9 1.6 2.8 6.3 1.8 4.2 21.7 2.7 0.2 0.0 0.1 170.5 11.4 4.0 0.9 6.0 3.4 2.4 1.3 2.9 20.4 0.5 0.5 0.0 0.0 0.0 0.1 1.3 60.6 2.8 0.7 4.1 0.8 3.2 34.1 6.8 2.9 3.6 61.8 1.1 25.6 0.0 0.5 0.7 0.4 0.1 1.2 0.3 0.7 0.0 0.3 12.5 2.4 0.0 0.5 2.2 10.7 7.9 0.8 2.4 30.9 0.6 2.5 0.1 0.2 IL34 "C16orf77, IL-34, MGC34647" ENSG00000157368 "Interleukin 34" Q6ZMJ4 16 70579895-70660682 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 106.3;skin 1: 62.0" "Cell type enhanced" "Detected in many" "Leydig cells: 18.3;Peritubular cells: 40.6;Sertoli cells: 19.7;Suprabasal keratinocytes: 20.5;Theca cells: 18.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 13 "eosinophil: 18.5" "Lineage enriched" "Detected in single" 185 "granulocytes: 18.5" "Cell line enhanced" "Detected in some" "ASC TERT1: 2.1;Hep G2: 2.7;HSkMC: 2.4;NTERA-2: 5.3;U-138 MG: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 57100 "Cluster 52: Eosinophils - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 5: NTERA-2 - Transcription" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (3.76e-3)" "prognostic favorable (7.41e-4)" "unprognostic (5.70e-2)" "unprognostic (1.02e-1)" "unprognostic (2.27e-2)" "prognostic favorable (9.69e-4)" "unprognostic (8.19e-2)" "unprognostic (1.59e-3)" "unprognostic (3.83e-2)" "unprognostic (6.11e-3)" "unprognostic (3.18e-2)" "unprognostic (9.92e-2)" "prognostic unfavorable (3.52e-8)" "unprognostic (6.47e-3)" "unprognostic (4.58e-2)" "unprognostic (5.83e-2)" "unprognostic (4.37e-2)" 4.4 22.9 17.1 3.9 18.1 0.1 8.6 8.5 23.3 9.6 23.1 4.0 5.1 2.9 1.0 25.5 3.2 6.7 4.4 22.5 14.5 5.7 2.5 5.0 9.1 13.0 11.7 1.6 1.9 1.0 12.5 0.5 14.1 6.2 2.2 1.2 16.0 3.8 9.6 62.0 6.4 2.5 10.1 106.3 2.4 3.5 19.0 3.9 5.1 2.5 5.0 4.8 13.4 11.6 0.0 0.6 0.1 0.1 0.2 2.1 0.2 0.1 1.8 0.2 0.2 0.4 0.0 0.0 0.3 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.9 0.0 1.6 2.4 0.1 0.1 0.0 0.2 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 5.3 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.3 0.0 0.0 0.0 3.6 0.1 0.1 0.1 0.2 0.0 0.0 0.3 0.7 0.1 1.4 0.0 18.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 18.1 8.5 23.3 22.5 14.5 13.0 11.7 14.1 10.1 19.0 11.6 2.8 0.0 1.8 2.9 0.1 8.3 1.6 3.4 2.2 1.2 15.7 14.7 0.4 1.5 4.9 0.0 4.2 0.1 0.5 0.0 0.0 7.4 0.2 0.5 0.3 6.1 0.0 0.0 12.7 2.0 0.9 9.0 0.0 0.1 0.0 0.0 3.6 0.1 3.8 5.0 11.4 0.1 2.0 0.0 4.2 0.3 18.3 0.4 12.4 5.6 0.0 15.2 0.0 1.5 1.0 0.8 0.1 40.6 0.1 2.4 0.2 0.3 1.2 0.8 19.7 2.0 8.1 0.1 0.4 7.8 20.5 0.8 0.3 18.8 0.5 1.9 INPP4B ENSG00000109452 "Inositol polyphosphate-4-phosphatase type II B" O15327 4 142023160-142847432 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 158.7;Early spermatids: 178.1;Excitatory neurons: 196.8;Inhibitory neurons: 614.4;Late spermatids: 291.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 30.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 150.4;SK-MEL-30: 66.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037681, HPA037682" Approved Approved Centrosome NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 23: Testis - Cell cycle regulation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Centrosome "HPA037681: AB_10670389, HPA037682: AB_10671377" "unprognostic (9.79e-2)" "unprognostic (1.11e-1)" "unprognostic (1.95e-1)" "unprognostic (9.25e-2)" "unprognostic (1.77e-1)" "unprognostic (8.24e-2)" "unprognostic (3.03e-3)" "unprognostic (5.76e-3)" "unprognostic (1.95e-2)" "unprognostic (3.16e-1)" "prognostic unfavorable (1.03e-4)" "unprognostic (8.58e-2)" "unprognostic (1.26e-2)" "unprognostic (2.79e-2)" "unprognostic (1.30e-1)" "unprognostic (4.58e-1)" "unprognostic (1.39e-2)" 9.9 4.0 5.2 6.7 6.7 2.1 18.3 3.2 6.4 13.1 0.3 5.8 4.6 5.4 3.9 7.5 7.3 7.9 17.4 5.5 3.4 5.4 1.8 6.5 10.8 1.3 2.7 5.7 2.5 2.0 1.3 5.7 1.9 4.7 5.1 1.7 2.7 4.7 7.9 3.6 5.5 7.3 0.0 6.8 5.8 18.6 7.3 5.9 4.3 5.2 6.9 14.0 8.7 6.0 27.7 11.4 7.3 3.6 5.5 3.4 1.4 32.5 37.9 8.2 15.3 3.1 150.4 0.8 8.9 29.4 12.6 41.1 0.0 37.9 19.1 0.1 1.1 6.6 4.0 0.1 1.8 1.4 5.0 5.9 5.2 5.8 19.4 24.7 4.8 0.0 0.0 1.5 17.9 49.1 1.1 0.0 0.3 16.8 8.1 0.3 24.7 1.4 11.3 50.3 0.6 0.7 3.7 11.2 66.6 4.3 34.2 4.9 3.1 18.8 22.6 28.0 0.3 0.4 0.1 0.1 4.4 29.7 49.5 6.1 0.2 0.0 5.2 0.0 10.1 0.0 30.4 13.6 0.1 0.1 20.6 8.9 0.5 17.0 0.0 0.1 17.4 5.9 5.2 6.7 3.2 6.4 5.5 3.4 1.3 2.7 1.9 0.0 7.3 6.0 13.4 0.0 0.6 158.7 2.6 6.6 9.5 7.0 4.0 7.5 49.0 15.5 42.2 7.2 20.2 9.2 0.0 1.7 8.7 8.7 5.9 12.2 178.1 19.8 58.2 13.2 8.9 6.1 196.8 30.6 5.1 5.1 19.4 5.4 6.3 0.6 6.4 0.3 8.1 6.7 614.4 3.5 4.1 2.8 4.9 291.9 13.7 3.9 72.9 47.8 1.3 0.9 2.1 79.4 57.6 76.3 0.2 6.4 4.5 20.5 10.1 0.9 35.7 0.8 85.5 5.2 84.7 2.5 1.9 1.9 2.6 1.9 60.4 1.8 4.3 42.9 JHY "C11orf63, FLJ23554" ENSG00000109944 "Junctional cadherin complex regulator" Q6NUN7 11 122882683-122963862 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 35.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 12.8;Endometrial ciliated cells: 41.5;Glandular and luminal cells: 8.7;Proximal tubular cells: 12.0;Respiratory ciliated cells: 19.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "GAMG: 13.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA039612, HPA040344, HPA077658, HPA077748" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Golgi apparatus" "HPA039612: AB_10674424, HPA040344: AB_2676931, HPA077658: AB_2732355, HPA077748: AB_2732360" "unprognostic (5.27e-2)" "unprognostic (1.12e-1)" "unprognostic (3.93e-2)" "prognostic favorable (7.94e-5)" "unprognostic (9.97e-5)" "unprognostic (1.64e-1)" "unprognostic (2.02e-3)" "unprognostic (1.94e-3)" "unprognostic (1.77e-1)" "unprognostic (1.49e-1)" "unprognostic (4.13e-2)" "unprognostic (2.97e-1)" "prognostic favorable (8.77e-4)" "unprognostic (6.46e-3)" "unprognostic (2.54e-1)" "prognostic unfavorable (2.58e-4)" "unprognostic (7.79e-2)" 6.0 1.8 1.7 2.2 2.7 1.1 3.6 3.4 2.4 3.1 17.3 3.5 1.5 2.1 2.7 1.8 7.4 2.6 2.2 1.8 3.8 7.8 0.4 4.5 2.2 4.1 5.4 3.2 2.8 5.6 4.8 1.3 3.8 3.5 1.7 1.6 1.4 2.5 0.2 1.9 1.9 2.0 3.8 2.5 2.0 35.7 3.2 3.2 5.1 0.8 2.0 2.6 1.8 3.6 2.8 3.9 2.2 0.1 0.6 0.4 0.7 5.9 6.8 2.5 1.1 0.3 10.3 0.1 1.5 9.1 13.6 2.4 2.7 1.4 1.1 9.5 2.8 0.1 1.8 0.1 0.9 1.7 4.7 2.8 7.4 0.4 0.6 6.3 3.8 4.1 0.0 0.1 2.0 1.8 0.1 0.6 0.3 8.2 3.5 1.0 0.0 1.3 7.0 3.2 5.8 4.2 7.1 3.9 2.6 2.8 4.7 0.6 1.2 7.9 1.0 0.2 4.8 0.1 0.0 0.1 2.1 2.1 5.3 0.5 0.3 0.1 1.3 0.1 1.8 1.1 1.3 1.7 2.4 0.6 0.9 1.0 0.4 2.4 0.1 0.6 0.3 0.5 1.7 2.7 3.4 2.4 1.8 3.8 4.1 5.4 3.8 3.8 3.2 3.6 4.4 12.8 4.4 0.0 1.1 0.0 0.0 0.0 0.0 0.0 3.3 3.2 0.0 0.0 7.4 5.5 0.0 0.2 2.2 0.0 3.9 5.5 0.0 41.5 3.1 1.1 0.0 0.0 0.0 1.4 0.9 2.2 0.0 8.7 0.0 2.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 2.6 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.7 0.0 0.0 12.0 19.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.3 1.8 1.3 0.0 0.0 KIAA0408 ENSG00000189367 KIAA0408 Q6ZU52 6 127438406-127459389 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.6;skeletal muscle: 28.3" "Group enriched" "Detected in some" 6 "Alveolar cells type 1: 93.0;Alveolar cells type 2: 27.1;Skeletal myocytes: 34.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 10.4;SCLC-21H: 33.3;SH-SY5Y: 17.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044035, HPA053341" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm Cytosol "HPA044035: AB_10964274, HPA053341: AB_2732578" "unprognostic (1.06e-1)" "unprognostic (4.36e-2)" "unprognostic (3.06e-1)" "unprognostic (1.09e-1)" "unprognostic (8.56e-4)" "unprognostic (1.00e-1)" "unprognostic (4.95e-2)" "unprognostic (6.05e-3)" "unprognostic (2.29e-1)" "unprognostic (5.94e-2)" "unprognostic (3.20e-2)" 16.8 2.3 16.9 0.9 18.4 0.0 3.7 20.1 32.6 4.3 8.0 9.7 0.9 2.9 1.8 6.2 2.0 1.6 2.1 18.2 17.4 1.2 0.7 13.2 0.3 16.7 16.9 2.5 0.8 0.0 13.9 0.3 17.2 4.3 3.6 8.7 1.8 1.1 28.3 1.0 4.3 1.8 18.0 2.0 5.4 4.0 17.7 0.3 0.9 10.4 0.2 6.0 3.6 19.6 0.0 2.1 10.4 0.0 0.8 1.7 0.0 0.2 1.3 1.1 2.7 0.0 0.0 0.0 0.0 0.2 7.0 0.0 1.0 0.0 1.6 0.8 0.2 0.0 0.0 0.0 0.1 0.0 0.0 4.0 0.0 4.3 0.0 0.9 0.0 1.2 0.0 0.0 1.2 0.0 4.7 0.0 4.8 0.0 0.0 0.0 2.6 0.0 0.2 0.0 33.3 17.8 0.0 0.0 0.2 0.0 0.0 1.1 0.0 5.3 0.8 0.0 1.9 0.0 0.0 0.0 4.7 0.3 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 18.4 20.1 32.6 18.2 17.4 16.7 16.9 17.2 18.0 17.7 19.6 0.4 93.0 27.1 0.0 0.0 0.0 0.1 0.0 0.0 3.3 0.0 0.4 0.2 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.1 0.7 0.0 0.3 8.4 0.0 0.0 0.0 0.3 0.3 0.6 0.9 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.1 3.6 1.1 0.0 34.3 0.5 1.0 0.1 0.0 0.0 0.1 0.1 3.4 0.0 0.0 KIAA1614 ENSG00000135835 KIAA1614 Q5VZ46 1 180912897-180951614 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 25.3" "Group enriched" "Detected in many" 13 "Bipolar cells: 95.3;Cone photoreceptor cells: 131.3;Rod photoreceptor cells: 176.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.3" "Cell line enhanced" "Detected in many" "RH-30: 17.8;SH-SY5Y: 44.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028227, HPA061684" Approved Approved "Nuclear membrane,Vesicles" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" "Nuclear membrane, Vesicles" "HPA028227: AB_10601765, HPA061684: AB_2684585" "unprognostic (3.23e-1)" "unprognostic (3.60e-2)" "unprognostic (3.17e-2)" "unprognostic (2.15e-2)" "unprognostic (1.05e-1)" "unprognostic (3.55e-2)" "unprognostic (8.76e-3)" "unprognostic (1.30e-1)" "unprognostic (1.38e-1)" "unprognostic (1.33e-1)" "unprognostic (3.15e-2)" "unprognostic (1.57e-1)" "unprognostic (8.61e-5)" "unprognostic (8.93e-2)" "unprognostic (8.88e-2)" "unprognostic (1.36e-2)" "unprognostic (1.35e-2)" 5.7 1.2 3.8 1.3 3.9 0.4 4.0 15.4 6.1 7.2 4.3 8.4 2.4 8.1 1.3 3.5 6.1 2.5 7.7 4.9 2.4 6.2 0.5 3.6 1.2 3.6 3.2 5.8 1.7 0.3 1.8 2.8 2.9 4.8 0.6 25.3 3.2 2.1 2.0 2.5 2.9 3.1 2.8 2.5 3.2 1.7 4.0 0.3 6.1 0.4 0.4 7.4 4.2 5.3 1.7 0.8 1.4 3.0 4.3 10.5 4.8 3.3 3.8 1.6 0.9 1.6 1.7 0.7 3.0 4.1 0.8 3.2 0.3 0.1 0.5 0.9 1.3 2.4 0.6 2.2 5.9 1.5 1.7 5.0 0.1 0.2 0.1 2.7 2.2 2.5 2.1 1.1 1.4 1.4 2.1 0.6 3.3 0.5 0.4 1.1 17.8 2.5 2.6 1.6 12.2 44.7 1.0 1.1 7.3 1.4 1.3 2.1 5.2 3.4 2.5 4.0 1.3 2.3 3.2 1.6 0.4 1.2 2.3 1.3 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.1 3.8 3.9 15.4 6.1 4.9 2.4 3.6 3.2 2.9 2.8 4.0 5.3 1.0 0.0 1.8 9.8 0.5 0.4 0.8 0.8 0.6 95.3 0.5 0.6 3.5 1.5 1.3 1.8 131.3 0.3 0.5 0.0 1.9 0.4 4.6 0.8 3.6 2.1 0.0 0.0 5.0 0.2 0.4 3.3 0.0 2.2 1.3 1.6 1.8 0.1 1.8 3.3 1.5 0.0 0.0 0.3 0.4 1.8 7.8 0.5 3.6 1.0 1.0 10.0 0.0 4.5 1.4 0.7 0.0 5.7 0.1 0.4 0.2 1.8 0.1 176.0 6.6 8.4 2.4 0.6 0.6 0.2 0.3 0.3 0.4 0.6 0.1 0.0 KITLG "DFNA69, FPH2, Kitl, KL-1, MGF, SCF, SF, SLF" ENSG00000049130 "KIT ligand" P21583 12 88492793-88580851 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Cell adhesion" "Growth factor" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 83.6;Collecting duct cells: 69.9;Excitatory neurons: 46.5;Inhibitory neurons: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 299.8;SK-BR-3: 118.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070395 Approved Approved Vesicles "Intracellular and membrane" NA NA 260000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA070395: AB_2686264" "unprognostic (7.13e-2)" "unprognostic (1.90e-1)" "unprognostic (5.00e-2)" "unprognostic (2.05e-1)" "unprognostic (2.70e-1)" "unprognostic (1.93e-2)" "prognostic unfavorable (4.01e-4)" "unprognostic (2.22e-3)" "unprognostic (5.61e-3)" "unprognostic (7.89e-2)" "unprognostic (5.47e-3)" "unprognostic (5.03e-2)" "prognostic favorable (5.81e-7)" "unprognostic (7.15e-2)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (1.54e-2)" 13.2 3.9 2.3 8.2 3.5 0.3 10.6 0.2 3.1 12.9 1.2 18.7 9.6 15.1 2.8 14.3 4.0 18.5 7.0 2.9 0.3 16.0 2.3 31.6 3.3 0.0 2.5 6.0 3.7 3.7 0.2 15.0 0.0 15.1 22.6 2.3 8.8 14.8 3.1 7.1 11.6 18.8 0.3 3.5 17.4 6.3 5.2 5.1 5.9 14.4 10.4 12.3 1.3 6.2 14.3 7.1 7.1 0.9 29.0 61.5 0.0 77.6 60.1 13.5 6.4 299.8 11.0 0.0 2.2 73.3 14.9 49.5 11.5 20.1 14.2 0.1 9.5 0.0 9.5 2.6 4.4 1.9 0.0 53.5 20.6 41.6 26.8 6.3 17.9 0.0 0.0 0.3 6.8 2.5 0.2 0.0 4.8 17.7 17.9 0.0 12.6 0.0 25.0 6.5 2.3 4.8 18.5 118.9 2.2 6.5 57.2 4.3 10.0 60.7 7.4 69.0 6.8 0.0 0.0 0.0 8.4 0.2 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.5 0.2 3.1 2.9 0.3 0.0 2.5 0.0 0.3 5.2 6.2 42.5 19.2 38.3 9.4 0.5 13.5 11.2 7.5 83.6 2.7 12.2 8.1 4.4 1.5 16.5 69.9 0.0 0.1 0.0 12.0 1.9 4.4 0.4 3.1 6.8 43.1 9.5 0.0 46.5 18.2 0.1 34.5 43.3 3.4 0.0 2.1 5.0 0.4 1.2 21.9 61.4 8.5 18.3 3.2 5.7 0.9 14.0 1.9 12.4 18.7 0.0 0.3 0.0 3.0 0.6 8.7 3.0 3.8 1.4 11.2 2.3 1.4 9.8 1.2 13.1 2.2 27.2 0.2 0.5 18.5 5.3 0.0 1.0 4.4 14.7 3.2 LAMA4 LAMA3 ENSG00000112769 "Laminin subunit alpha 4" Q16363 6 112107931-112254939 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 115.7;Early spermatids: 114.7;Extravillous trophoblasts: 119.1;Fibroblasts: 149.2;Leydig cells: 166.5;Microglial cells: 124.6;Oligodendrocyte precursor cells: 160.4;Theca cells: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 330.5;ASC TERT1: 512.5;HSkMC: 405.5;hTERT-RPE1: 256.0;HUVEC TERT2: 441.3;TIME: 404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015693, CAB078156" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 320000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "CAB078156: AB_2665814, HPA015693: AB_1852687" "unprognostic (1.87e-2)" "unprognostic (6.48e-2)" "unprognostic (8.37e-2)" "unprognostic (2.39e-2)" "unprognostic (1.04e-1)" "unprognostic (1.15e-1)" "unprognostic (2.52e-2)" "unprognostic (5.07e-2)" "unprognostic (4.59e-2)" "unprognostic (2.93e-2)" "unprognostic (9.06e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (4.40e-3)" "unprognostic (1.85e-1)" "unprognostic (2.80e-2)" "unprognostic (1.15e-2)" 116.2 9.4 17.6 34.0 17.1 0.5 59.9 11.7 12.9 77.0 12.6 82.6 17.2 77.5 18.5 35.6 115.2 37.3 51.2 12.3 17.9 9.9 4.4 80.8 11.5 12.7 16.3 23.2 4.9 8.6 13.6 68.0 14.7 35.4 34.0 1.3 38.4 40.7 10.6 17.7 34.5 107.8 11.4 1.5 36.7 18.7 22.6 5.0 23.2 18.6 8.9 65.1 40.3 11.4 0.3 0.1 18.8 0.6 330.5 512.5 0.3 91.4 55.8 8.9 1.4 0.0 36.1 0.0 58.0 154.9 19.8 0.3 4.0 0.6 1.5 0.3 46.4 0.0 44.4 0.0 69.6 0.1 0.3 405.5 0.1 64.9 0.2 256.0 441.3 0.0 0.4 0.4 1.7 0.0 0.1 0.3 1.1 0.0 15.1 0.2 0.2 0.3 134.0 2.8 0.4 2.1 14.2 0.4 68.5 1.5 0.4 0.2 404.9 145.1 7.6 160.6 29.1 0.0 0.3 0.3 33.5 0.2 191.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 17.1 11.7 12.9 12.3 17.9 12.7 16.3 14.7 11.4 22.6 11.4 115.7 3.2 4.5 45.4 0.1 22.7 1.4 2.9 8.6 1.6 5.4 9.4 53.3 2.8 10.4 3.7 0.0 1.0 0.6 0.0 3.9 0.7 114.7 6.2 24.8 103.5 0.0 2.7 27.4 0.7 119.1 149.2 3.6 10.5 1.3 3.5 36.0 35.3 3.0 0.0 6.3 0.8 20.3 1.6 20.8 47.0 166.5 2.0 56.9 124.6 0.6 0.0 0.0 160.4 2.0 0.7 0.0 81.3 1.5 1.5 0.0 0.1 1.7 0.5 65.7 5.4 98.2 1.3 1.2 5.0 18.6 3.0 2.7 117.4 0.0 12.9 LDOC1 "BCUR1, Mar7, Mart7, RTL7, SIRH7" ENSG00000182195 "LDOC1 regulator of NFKB signaling" O95751 X 141111605-141177129 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 123.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 43.0;Proximal tubular cells: 43.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 6.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 24.7;MCF7: 31.9;PC-3: 34.3;U-251 MG: 21.9" "Region enriched" "Detected in many" 5 "cerebellum: 19.2" "HPA051768, HPA061842" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Nucleoli" "HPA051768: AB_2681599, HPA061842: AB_2684624" "unprognostic (4.09e-1)" "unprognostic (4.72e-2)" "unprognostic (1.88e-1)" "unprognostic (1.73e-3)" "unprognostic (2.47e-1)" "unprognostic (2.42e-1)" "unprognostic (4.51e-2)" "unprognostic (2.08e-2)" "unprognostic (8.92e-2)" "unprognostic (1.21e-1)" "unprognostic (6.40e-3)" "unprognostic (1.21e-1)" "unprognostic (1.27e-2)" "unprognostic (1.98e-2)" "unprognostic (3.06e-2)" "unprognostic (4.38e-3)" "unprognostic (2.76e-2)" 32.3 34.0 4.7 0.9 5.5 0.1 28.0 2.9 8.5 45.8 0.2 18.8 0.9 53.9 1.8 21.4 48.5 1.6 15.1 6.2 5.8 33.2 4.8 19.6 0.8 5.3 5.0 46.8 19.3 10.5 123.3 0.0 5.0 34.3 0.3 3.4 55.1 5.9 5.5 31.5 12.5 2.0 1.2 14.2 18.4 10.8 5.0 0.9 53.7 0.4 0.7 33.1 30.6 6.0 0.0 24.7 3.0 8.4 5.0 6.2 0.0 5.0 5.8 6.3 8.8 0.0 8.0 0.0 4.2 7.7 6.1 10.4 3.4 7.1 4.5 0.0 6.6 0.0 11.7 0.0 2.0 0.0 1.9 10.9 3.6 5.5 2.9 5.1 5.7 0.0 0.1 0.0 5.7 31.9 0.0 0.0 3.3 0.0 34.3 0.0 2.7 0.0 7.7 4.7 0.0 3.2 0.0 4.0 0.0 1.6 5.1 0.0 11.9 0.0 6.8 0.0 21.9 0.0 0.0 0.0 3.5 0.0 0.0 3.1 0.0 0.0 1.2 0.0 0.8 0.9 2.5 0.8 0.2 2.1 2.2 1.4 0.0 6.4 0.0 1.4 2.6 1.0 4.7 5.5 2.9 8.5 6.2 5.8 5.3 5.0 5.0 1.2 5.0 6.0 8.6 0.0 5.3 4.2 4.9 6.0 16.8 4.6 16.5 29.3 23.8 20.2 2.2 30.0 8.2 23.9 8.4 2.8 5.7 0.1 43.0 13.8 0.7 7.8 13.5 12.8 5.4 0.8 9.4 14.0 1.8 16.1 3.6 6.0 2.5 8.8 12.8 0.1 0.9 20.2 9.9 0.4 8.2 0.3 1.8 1.1 22.1 1.0 3.6 7.5 0.3 21.2 5.2 7.1 15.0 13.7 0.2 38.7 0.9 11.9 0.0 43.8 4.6 13.0 13.1 15.3 26.2 0.9 7.6 16.7 6.8 1.5 5.2 13.5 0.3 15.0 LOXL1 "LOL, LOXL" ENSG00000129038 "Lysyl oxidase like 1" Q08397 15 73925989-73952137 "Disease related genes, Plasma proteins, Predicted secreted proteins" Oxidoreductase Glaucoma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 92.3;Extravillous trophoblasts: 145.8;Fibroblasts: 76.0;Smooth muscle cells: 32.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 3.4" "Lineage enriched" "Detected in single" 34 "T-cells: 3.4" "Cell line enhanced" "Detected in many" "BJ: 66.5;BJ hTERT+: 75.2;hTERT-RPE1: 73.7;U-87 MG: 61.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042111, HPA063583" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" No No 280000 "Cluster 35: T-regs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA042111: AB_10794412, HPA063583: AB_2685050" "unprognostic (6.39e-2)" "unprognostic (1.23e-1)" "unprognostic (3.05e-2)" "unprognostic (3.61e-2)" "prognostic unfavorable (9.52e-5)" "unprognostic (7.95e-2)" "unprognostic (2.49e-1)" "unprognostic (2.44e-1)" "unprognostic (3.10e-1)" "unprognostic (1.57e-1)" "unprognostic (1.63e-1)" "unprognostic (9.83e-2)" "unprognostic (1.14e-3)" "unprognostic (4.51e-2)" "unprognostic (5.81e-2)" "unprognostic (1.41e-2)" "unprognostic (9.76e-2)" 12.4 3.1 1.4 5.4 0.8 0.8 6.8 0.2 1.4 12.7 12.3 10.2 1.9 16.0 1.4 4.7 8.3 5.0 27.9 1.7 1.9 8.7 1.5 10.1 4.4 1.4 1.7 8.0 3.3 2.2 9.2 8.0 1.1 15.3 1.4 0.0 7.6 11.9 3.8 6.4 5.6 4.9 0.8 3.2 7.8 2.4 1.9 0.9 5.2 1.9 2.3 16.6 14.8 0.6 3.3 0.0 0.9 0.0 45.6 54.8 2.2 66.5 75.2 27.6 48.7 1.3 1.7 0.0 12.1 49.1 6.9 19.9 0.3 0.2 6.5 0.0 4.3 0.2 2.0 0.3 6.2 0.0 0.1 45.0 0.0 20.8 0.2 73.7 1.0 1.2 0.0 0.3 33.3 2.4 0.4 1.3 6.3 4.4 45.1 0.0 38.7 0.6 2.5 12.0 5.5 0.0 2.0 0.4 0.0 6.5 0.4 0.0 4.9 53.8 47.0 42.8 25.8 0.2 0.0 0.0 61.9 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.9 0.0 1.3 0.7 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 3.4 0.2 1.4 0.8 0.2 1.4 1.7 1.9 1.4 1.7 1.1 0.8 1.9 0.6 4.1 0.0 0.6 3.3 0.1 5.9 7.6 6.0 4.0 0.9 2.3 4.8 92.3 2.8 0.9 9.2 0.0 2.2 0.6 0.1 3.9 5.2 1.7 9.2 8.0 4.1 3.5 0.0 0.5 1.3 145.8 76.0 8.6 9.3 1.3 5.5 12.1 0.1 6.6 0.0 0.4 0.6 2.0 0.0 6.2 1.3 9.9 0.9 10.6 0.0 0.1 6.4 0.0 1.5 0.3 12.2 0.1 21.1 0.1 4.8 0.4 2.5 1.2 0.4 0.0 6.0 32.7 8.9 4.9 2.4 3.4 5.1 3.4 0.3 1.1 5.0 LRRC7 "densin-180, KIAA1365" ENSG00000033122 "Leucine rich repeat containing 7" 1 69567922-70151945 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 20.2" "Group enriched" "Detected in many" 20 "Excitatory neurons: 1132.4;Inhibitory neurons: 996.9;Oligodendrocyte precursor cells: 1038.0;Oligodendrocytes: 408.2" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "amygdala: 6.9;basal ganglia: 17.0;cerebral cortex: 20.2;hippocampal formation: 17.7;thalamus: 11.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HaCaT: 12.6;HEL: 44.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA005625 Supported "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Nucleoplasm, Centrosome" "HPA005625: AB_1853340" "unprognostic (2.81e-2)" "unprognostic (1.62e-2)" "unprognostic (1.51e-1)" "unprognostic (2.98e-3)" "unprognostic (2.47e-1)" "unprognostic (1.73e-1)" "unprognostic (1.04e-1)" "unprognostic (3.50e-2)" "unprognostic (4.84e-3)" "unprognostic (2.92e-2)" "unprognostic (1.06e-3)" "unprognostic (1.46e-1)" "unprognostic (5.64e-6)" "unprognostic (1.31e-2)" "unprognostic (1.74e-2)" "unprognostic (5.13e-3)" "unprognostic (2.08e-3)" 0.1 0.2 6.9 0.1 17.0 0.2 0.0 0.0 20.2 0.2 0.0 0.4 0.1 0.2 0.1 0.2 0.0 1.0 1.4 17.7 1.7 0.8 0.2 0.0 0.1 0.0 2.2 0.1 0.8 0.1 0.0 0.2 0.0 0.3 0.6 1.5 0.0 0.1 1.0 0.2 0.2 0.2 0.0 0.0 0.2 1.6 11.4 0.0 2.2 0.0 0.0 0.1 0.1 2.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.4 4.4 0.0 0.0 12.6 0.3 0.0 0.0 0.0 0.6 44.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 4.7 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.1 0.0 0.0 0.0 0.0 6.9 17.0 0.0 20.2 17.7 1.7 0.0 2.2 0.0 0.0 11.4 2.9 0.8 0.0 0.0 41.4 2.5 0.8 0.6 0.4 1.8 44.4 0.3 0.3 6.2 2.8 0.2 0.0 2.1 0.4 2.4 0.0 0.0 0.0 29.4 0.5 1.4 1.2 0.0 3.2 1132.4 0.0 0.5 1.8 0.0 1.4 0.0 0.6 2.9 6.5 0.3 6.7 996.9 0.0 0.0 2.8 3.6 6.3 0.6 0.5 5.4 17.8 1.7 1.0 2.1 1038.0 408.2 0.0 0.0 3.0 1.3 0.9 0.0 1.6 0.1 8.3 0.0 1.4 1.5 9.2 3.0 0.5 1.3 0.1 2.3 0.1 0.0 0.1 LRRC75A "C17orf76, FAM211A, FLJ35696" ENSG00000181350 "Leucine rich repeat containing 75A" Q8NAA5 17 16441577-16492193 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 47.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 62.1;SK-MEL-30: 21.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028528, HPA065840" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 36: HEL - Hemostasis" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nucleoli, Cytosol" "HPA028528: AB_10600755, HPA065840: " "unprognostic (1.09e-1)" "unprognostic (5.60e-2)" "unprognostic (5.79e-2)" "unprognostic (3.85e-5)" "unprognostic (3.93e-2)" "unprognostic (3.23e-2)" "unprognostic (3.44e-1)" "unprognostic (7.66e-3)" "unprognostic (7.74e-2)" "unprognostic (2.84e-1)" "prognostic favorable (7.46e-5)" "unprognostic (8.36e-2)" "unprognostic (4.28e-3)" "unprognostic (8.84e-2)" "unprognostic (1.82e-1)" "unprognostic (1.17e-3)" "unprognostic (2.06e-1)" 5.5 21.5 6.8 6.4 5.0 16.1 0.5 1.8 7.7 1.3 0.1 20.2 47.4 4.0 0.2 2.1 1.3 3.1 2.4 6.8 6.5 2.0 0.6 4.6 5.6 4.1 6.7 4.4 7.0 4.7 3.1 3.4 5.1 1.9 9.0 2.3 1.3 1.1 2.9 2.2 44.0 2.3 3.4 21.5 7.4 10.6 5.1 0.5 4.9 0.6 1.6 1.5 0.5 5.3 8.9 6.3 7.6 6.0 0.2 0.2 1.3 2.4 0.4 1.8 1.5 7.9 2.6 0.6 6.6 0.2 3.7 3.7 0.2 0.0 0.0 3.4 6.5 62.1 3.9 0.0 0.3 1.5 7.3 0.0 0.0 0.4 0.0 3.2 2.3 9.4 3.9 1.7 0.1 12.8 15.3 6.7 1.7 20.3 0.7 5.8 5.5 0.8 0.4 1.8 16.6 4.6 0.6 1.8 21.7 3.3 1.4 1.4 0.0 2.2 10.5 6.7 11.9 12.2 2.6 2.0 0.8 5.1 7.0 0.0 0.5 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.7 0.3 0.4 1.0 0.0 0.0 0.4 6.8 5.0 1.8 7.7 6.8 6.5 4.1 6.7 5.1 3.4 5.1 5.3 40.5 41.7 69.7 10.7 21.6 0.0 9.6 0.0 2.2 9.1 24.9 13.3 0.7 14.3 19.8 1.8 6.2 16.1 24.8 52.5 19.6 3.9 7.1 30.0 61.0 14.7 24.7 9.7 5.3 7.1 20.4 30.5 2.0 58.7 29.7 25.0 11.0 10.0 12.0 3.3 3.6 52.2 0.0 13.9 0.0 8.0 16.4 22.9 0.0 1.0 7.7 21.3 2.1 4.0 4.2 6.2 36.0 11.3 12.0 8.7 65.4 19.4 8.7 18.2 13.1 22.9 19.4 8.0 6.5 1.1 0.0 16.7 18.6 66.3 66.0 7.5 LSAMP "IGLON3, LAMP" ENSG00000185565 "Limbic system associated membrane protein" Q13449 3 115802363-117139389 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.9;retina: 41.3" "Group enriched" "Detected in many" 9 "Astrocytes: 3381.0;Excitatory neurons: 1001.8;Inhibitory neurons: 2137.4;Oligodendrocyte precursor cells: 2480.6;Oligodendrocytes: 933.9" "Cancer enhanced" "Detected in many" "glioma: 13.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 11.0;SH-SY5Y: 22.5;WM-115: 55.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054051, HPA076122" Enhanced Cytosol NA NA 150000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 58: Brain - Synaptic function" "Cluster 17: WM-115 - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol "HPA054051: AB_2682358, HPA076122: AB_2686779" "unprognostic (4.18e-2)" "unprognostic (2.54e-1)" "unprognostic (9.97e-3)" "unprognostic (6.03e-2)" "unprognostic (9.63e-2)" "unprognostic (4.15e-3)" "unprognostic (6.81e-2)" "unprognostic (2.70e-2)" "unprognostic (5.71e-2)" "unprognostic (6.82e-3)" "unprognostic (1.26e-1)" "unprognostic (6.03e-2)" "unprognostic (1.92e-2)" "unprognostic (1.28e-2)" "unprognostic (1.06e-1)" "unprognostic (5.23e-5)" "unprognostic (1.31e-2)" 3.1 15.7 47.8 5.6 45.4 1.0 1.7 22.6 73.9 21.8 0.0 9.9 2.0 5.0 3.1 3.9 3.1 13.5 2.3 64.2 36.3 2.6 0.8 10.6 4.9 37.5 32.2 5.5 14.4 8.9 3.8 1.0 37.8 26.1 3.8 41.3 1.2 7.3 0.2 5.1 2.6 3.8 28.5 1.9 3.8 4.6 56.4 1.2 5.0 0.2 6.7 6.5 4.8 31.9 0.2 3.2 11.0 0.3 1.1 3.4 1.1 1.0 0.5 0.4 1.1 0.2 0.7 0.8 0.2 6.0 0.3 0.2 0.2 0.1 0.5 0.5 0.1 0.3 1.0 0.3 0.2 0.8 0.5 2.8 0.0 1.3 0.1 0.2 0.1 1.3 0.4 1.2 0.0 0.3 1.3 0.8 4.1 0.1 0.9 0.2 0.2 0.2 2.8 1.1 2.4 22.5 0.0 0.2 3.5 4.5 0.3 0.8 0.0 2.0 1.5 2.7 0.6 1.3 1.2 0.3 0.4 0.3 55.9 0.9 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.3 0.2 0.1 0.4 0.0 0.1 0.1 0.1 0.0 47.8 45.4 22.6 73.9 64.2 36.3 37.5 32.2 37.8 28.5 56.4 31.9 0.5 0.0 1.1 3381.0 0.6 7.6 0.3 0.0 0.0 54.2 1.2 0.4 25.5 4.3 0.6 0.0 2.1 0.2 0.0 0.0 0.0 0.0 22.5 0.9 26.5 5.8 0.0 0.0 1001.8 3.6 0.0 25.0 2.6 1.1 0.0 20.1 4.2 0.0 0.3 220.4 2137.4 0.0 0.0 0.0 3.2 22.2 126.2 1.9 56.9 111.5 0.0 126.9 0.0 2480.6 933.9 0.4 0.0 91.7 1.0 18.3 0.0 0.2 0.0 11.3 0.0 0.1 4.0 0.9 0.5 0.6 5.1 0.0 0.4 4.9 0.0 0.6 MAP6 "FLJ41346, KIAA1878, MAP6-N, STOP" ENSG00000171533 "Microtubule associated protein 6" Q96JE9 11 75586918-75669038 "Predicted intracellular proteins" Transport Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 76.8;retina: 96.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 81.2;Cone photoreceptor cells: 158.4;Excitatory neurons: 75.8;Horizontal cells: 50.5;Inhibitory neurons: 43.3;Late spermatids: 41.9" "Cancer enhanced" "Detected in many" "glioma: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AF22: 37.8;CACO-2: 38.1;HDLM-2: 21.5;SCLC-21H: 62.4;SH-SY5Y: 31.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015442, CAB022600, HPA039061, HPA039062" Enhanced Uncertain "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "CAB015442: AB_2140997, CAB022600: , HPA039061: AB_2676325, HPA039062: AB_2676326" "unprognostic (3.04e-2)" "unprognostic (6.18e-2)" "unprognostic (3.15e-2)" "unprognostic (9.07e-2)" "unprognostic (7.54e-2)" "unprognostic (4.49e-2)" "unprognostic (8.29e-2)" "unprognostic (2.51e-2)" "unprognostic (5.99e-2)" "unprognostic (7.99e-2)" "prognostic favorable (3.41e-4)" "prognostic favorable (9.15e-4)" "unprognostic (2.43e-2)" "unprognostic (3.96e-3)" "unprognostic (8.09e-3)" "unprognostic (1.77e-1)" "unprognostic (2.03e-1)" 4.8 19.0 68.3 2.0 68.0 0.0 3.5 50.7 70.6 10.6 64.4 23.0 1.7 18.1 21.0 4.2 40.7 6.4 8.6 67.7 71.5 17.0 1.2 7.8 0.7 70.2 64.6 8.0 3.6 22.0 76.8 1.5 70.8 17.8 3.5 96.1 3.6 21.1 1.0 8.1 4.8 13.1 52.9 2.4 10.7 18.6 68.5 0.8 7.9 1.3 0.5 7.1 8.4 59.7 0.2 0.7 37.8 0.1 0.1 0.0 0.0 3.8 0.2 0.3 0.0 38.1 0.1 0.6 1.4 6.3 1.3 0.0 3.4 0.5 0.0 21.5 0.5 0.0 0.0 0.0 1.0 0.0 0.0 2.1 0.5 0.1 0.2 5.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 5.9 0.0 2.9 0.0 0.0 0.1 0.1 0.5 62.4 31.7 4.6 0.0 0.0 0.8 0.0 0.0 0.9 0.0 0.1 0.1 0.5 0.0 0.0 0.0 6.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.3 68.0 50.7 70.6 67.7 71.5 70.2 64.6 70.8 52.9 68.5 59.7 1.2 3.2 3.7 25.8 0.1 0.8 1.7 0.7 0.0 81.2 0.8 1.8 8.4 1.5 3.1 11.0 158.4 0.2 0.2 0.0 1.9 0.1 27.7 28.2 4.6 1.6 13.1 0.0 75.8 0.2 0.0 2.9 0.0 0.8 0.0 0.8 2.2 0.3 0.1 50.5 43.3 0.0 6.1 0.0 1.1 41.9 7.5 0.3 5.4 1.9 0.0 18.7 0.0 13.0 13.3 0.2 0.0 18.4 0.1 1.4 0.0 1.2 25.4 10.2 0.0 1.9 5.7 23.5 4.3 0.1 0.4 0.0 0.3 0.1 0.0 0.4 MBD5 "FLJ11113, KIAA1461" ENSG00000204406 "Methyl-CpG binding domain protein 5" Q9P267 2 148021011-148516971 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 317.4;Excitatory neurons: 510.1;Inhibitory neurons: 456.0;Microglial cells: 288.6;Oligodendrocyte precursor cells: 604.2;Oligodendrocytes: 438.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035964 Supported Nucleoplasm,Midbody Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Midbody" "HPA035964: AB_2674891" "unprognostic (1.10e-2)" "unprognostic (1.02e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (3.72e-4)" "unprognostic (5.81e-2)" "unprognostic (2.12e-1)" "unprognostic (2.22e-2)" "unprognostic (1.65e-1)" "unprognostic (9.86e-2)" "unprognostic (7.72e-2)" "unprognostic (2.00e-1)" "unprognostic (1.94e-1)" "unprognostic (2.39e-2)" "unprognostic (9.12e-2)" "unprognostic (1.12e-1)" "unprognostic (6.59e-2)" "unprognostic (1.82e-1)" 2.5 3.2 3.7 2.2 4.3 2.0 2.3 7.2 5.1 3.1 0.5 5.2 1.8 3.2 1.6 2.6 2.2 3.2 2.8 3.9 3.1 3.4 2.0 2.3 2.4 2.2 2.2 3.7 1.7 4.1 3.8 3.0 2.1 3.0 1.9 5.7 1.8 2.5 2.8 1.9 2.3 2.7 2.0 2.6 2.7 3.1 3.3 4.2 3.4 3.0 2.2 3.7 2.2 4.1 1.1 1.1 4.4 4.1 3.5 3.6 2.9 4.0 3.9 3.1 2.3 2.8 2.9 1.9 0.9 3.4 1.7 0.8 3.1 5.1 4.1 1.6 1.6 3.5 2.8 1.5 2.0 0.6 0.6 2.9 4.1 4.5 3.3 5.0 4.1 2.7 1.9 3.6 4.8 2.7 1.5 2.7 2.2 2.5 1.7 1.6 1.2 0.8 3.2 3.8 2.9 3.5 3.2 1.6 3.0 3.2 2.3 3.4 2.8 3.7 1.8 0.6 1.9 2.4 1.1 1.5 4.8 1.6 3.6 0.8 0.1 0.5 0.3 0.1 0.2 0.2 0.3 0.3 0.2 0.2 0.3 0.4 0.2 0.2 0.3 0.3 0.1 0.1 3.7 4.3 7.2 5.1 3.9 3.1 2.2 2.2 2.1 2.0 3.3 4.1 27.3 16.0 13.7 317.4 23.4 3.8 11.9 4.1 10.8 24.7 16.5 15.0 10.5 11.5 14.8 12.9 37.5 7.3 23.8 5.0 3.9 18.6 94.5 14.8 25.8 15.2 11.5 36.6 510.1 15.7 9.8 15.5 12.2 18.0 3.8 35.9 15.0 8.4 7.0 13.5 456.0 4.9 6.1 16.9 3.3 37.6 18.0 15.1 0.0 288.6 13.6 8.1 24.7 604.2 438.3 20.4 4.6 10.5 22.8 7.8 9.4 14.0 8.5 17.4 6.6 16.5 16.8 15.7 9.4 10.4 3.3 8.5 27.7 23.7 5.8 12.6 METTL24 "C6orf186, dJ71D21.2" ENSG00000053328 "Methyltransferase like 24" Q5JXM2 6 110245928-110358272 "Predicted secreted proteins" "Methyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "smooth muscle: 14.2" "Group enriched" "Detected in some" 4 "Astrocytes: 30.0;Excitatory neurons: 23.8;Inhibitory neurons: 28.7;Late spermatids: 8.6;Oligodendrocyte precursor cells: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 3.5" "Lineage enriched" "Detected in single" 29 "T-cells: 3.5" "Cell line enhanced" "Detected in some" "HHSteC: 1.0;SCLC-21H: 1.6;SuSa: 1.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA037441, HPA037442" Uncertain "Secreted - unknown location" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA037441: AB_10670933, HPA037442: AB_10696931" "unprognostic (6.62e-2)" "unprognostic (1.15e-1)" "unprognostic (9.31e-3)" "unprognostic (5.02e-2)" "unprognostic (5.21e-3)" "unprognostic (1.46e-1)" "unprognostic (6.12e-2)" "unprognostic (2.06e-1)" "unprognostic (3.98e-1)" "unprognostic (1.42e-1)" "unprognostic (8.45e-2)" "unprognostic (5.96e-2)" "unprognostic (1.54e-4)" "unprognostic (4.08e-2)" "unprognostic (1.23e-2)" "unprognostic (1.63e-2)" "unprognostic (4.78e-3)" 1.8 1.6 1.4 1.6 2.3 0.0 1.7 2.1 1.9 3.9 8.1 5.9 1.4 7.5 2.2 4.0 6.0 5.8 3.0 1.7 1.8 3.9 0.9 1.6 0.1 1.6 2.2 5.6 1.3 2.5 2.1 0.4 1.4 4.9 4.2 1.4 0.4 7.1 0.0 0.5 2.1 14.2 2.0 0.7 2.4 2.1 1.8 1.0 1.3 1.1 0.6 4.7 1.6 1.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.9 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 2.3 2.1 1.9 1.7 1.8 1.6 2.2 1.4 2.0 1.8 1.2 0.0 0.0 0.0 30.0 0.3 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.9 0.4 1.5 0.1 0.0 0.0 23.8 0.0 0.0 0.8 0.0 0.4 0.0 0.5 0.0 0.0 0.0 1.7 28.7 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 3.7 0.0 0.6 0.0 31.7 5.4 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.3 2.1 0.0 1.0 0.0 0.0 0.3 0.1 0.0 0.0 MFAP2 "MAGP, MAGP-1" ENSG00000117122 "Microfibril associated protein 2" P55001 1 16974502-16980632 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 81.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 197.8;Fibroblasts: 75.8;Granulosa cells: 93.3;Leydig cells: 53.7;Peritubular cells: 63.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 249.4;ASC TERT1: 249.6;HUVEC TERT2: 263.1;SH-SY5Y: 212.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA007354 Enhanced "Secreted to extracellular matrix" NA NA 210000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA007354: AB_1079365" "unprognostic (5.10e-2)" "unprognostic (3.81e-2)" "unprognostic (2.62e-1)" "unprognostic (2.92e-2)" "unprognostic (4.86e-1)" "unprognostic (1.53e-3)" "unprognostic (3.72e-3)" "unprognostic (2.21e-1)" "unprognostic (1.85e-2)" "unprognostic (1.98e-1)" "unprognostic (9.45e-3)" "unprognostic (9.12e-2)" "prognostic unfavorable (2.52e-8)" "unprognostic (2.18e-3)" "unprognostic (1.34e-1)" "unprognostic (1.93e-1)" "unprognostic (5.66e-3)" 36.6 4.2 0.4 13.3 0.6 0.1 22.7 0.5 1.1 81.8 1.6 15.0 5.0 61.4 22.1 6.1 19.0 73.2 13.8 0.5 0.6 9.4 1.6 20.1 4.2 0.7 0.9 35.8 18.8 4.5 13.2 42.4 0.7 22.1 4.8 4.9 16.5 12.1 2.6 27.6 12.1 30.6 0.5 2.7 8.3 11.2 0.7 1.6 9.5 3.0 2.3 22.5 36.7 0.6 0.0 0.2 93.2 0.3 249.4 249.6 6.2 26.3 102.5 39.7 73.7 24.1 1.1 0.0 82.6 89.7 0.1 0.1 7.2 7.7 15.9 0.1 78.0 0.0 37.1 2.1 23.4 0.1 0.1 104.4 18.8 109.4 42.7 113.1 263.1 0.0 0.2 16.2 19.2 12.5 0.1 0.1 108.8 0.5 0.8 1.5 0.0 4.0 0.9 0.3 5.0 212.1 9.0 36.6 9.6 71.1 11.9 13.0 75.6 65.6 128.4 51.7 2.8 0.1 0.3 0.2 53.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.5 1.1 0.5 0.6 0.7 0.9 0.7 0.5 0.7 0.6 5.5 0.0 1.7 0.0 0.1 6.6 7.8 28.7 8.0 0.2 2.1 3.9 0.9 2.8 10.7 3.7 0.0 4.5 0.0 0.1 0.0 1.3 12.9 5.6 28.7 7.1 10.1 0.0 0.0 0.8 197.8 75.8 2.0 8.3 0.0 93.3 1.4 0.0 7.4 0.0 0.0 0.4 12.2 0.0 7.7 7.6 53.7 0.6 17.8 2.8 0.0 27.7 0.0 0.0 0.0 1.9 0.0 63.9 0.5 1.5 0.0 0.0 1.9 0.8 0.0 3.3 14.7 3.2 8.7 0.6 6.3 29.0 0.9 0.5 0.2 1.2 MMP2 "CLG4, CLG4A, TBE-1" ENSG00000087245 "Matrix metallopeptidase 2" P08253 16 55389700-55506691 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 1062.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 222.4;Extravillous trophoblasts: 467.9;Fibroblasts: 815.9;Leydig cells: 340.2;Peritubular cells: 419.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 5619.3;ASC TERT1: 1623.2;hTERT-RPE1: 6400.4;U-87 MG: 1812.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001939, CAB002788" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 1600000000 220000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB002788: , HPA001939: AB_1079395" "unprognostic (7.26e-2)" "unprognostic (1.36e-3)" "unprognostic (1.66e-1)" "unprognostic (2.14e-3)" "unprognostic (5.03e-2)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (9.36e-3)" "unprognostic (4.81e-3)" "unprognostic (3.79e-2)" "unprognostic (4.59e-3)" "unprognostic (6.12e-2)" "unprognostic (1.28e-3)" "unprognostic (1.59e-2)" "unprognostic (8.00e-2)" "unprognostic (8.98e-2)" "unprognostic (4.63e-2)" 518.9 68.3 3.9 135.1 4.0 1.2 328.9 4.9 7.8 514.1 9.4 173.8 57.4 453.6 192.6 121.5 190.6 1062.9 212.8 3.6 5.3 43.7 15.6 279.7 28.1 7.6 4.9 271.1 42.8 13.8 14.7 225.0 5.4 116.8 171.3 11.4 124.1 137.5 60.8 455.6 177.3 468.5 6.7 58.3 134.0 49.6 8.6 19.8 113.5 66.1 30.3 660.8 238.1 10.0 6.5 3.9 192.0 2.4 5619.3 1623.2 312.7 501.4 1146.1 99.4 79.0 0.2 2.1 0.5 391.7 891.0 37.0 54.2 1.2 4.6 57.0 0.7 0.9 0.7 12.9 3.0 530.6 0.4 14.8 1396.8 1.7 512.4 4.4 6400.4 651.1 0.5 0.7 2.4 334.7 0.0 0.4 8.2 152.4 0.5 1.6 0.4 46.1 0.9 16.1 7.6 3.2 345.0 93.3 0.8 2.1 849.0 1.6 36.0 924.6 1546.0 144.9 300.5 66.9 1.0 0.6 2.2 1812.3 28.3 289.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.0 4.9 7.8 3.6 5.3 7.6 4.9 5.4 6.7 8.6 10.0 38.4 0.0 0.5 0.0 0.0 122.1 14.1 48.8 9.1 30.5 3.1 16.8 4.4 0.0 3.1 11.0 0.0 5.6 0.5 0.1 0.0 2.5 12.5 7.7 222.4 46.9 28.2 0.0 0.0 0.4 467.9 815.9 12.2 5.4 0.0 0.0 13.2 0.1 28.2 1.7 0.2 0.1 2.0 1.6 180.7 40.2 340.2 11.8 128.1 27.2 0.0 7.7 0.0 5.0 0.0 9.3 0.0 419.0 2.8 5.6 0.0 0.2 1.1 2.5 13.1 80.0 65.3 1.2 2.8 6.6 102.3 17.2 10.3 35.2 0.0 4.4 MSRB3 "DFNB74, DKFZp686C1178, FLJ36866" ENSG00000174099 "Methionine sulfoxide reductase B3" Q8IXL7 12 65278643-65491430 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 12 "Cardiomyocytes: 2801.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 41.6" "Lineage enhanced" "Detected in many" "granulocytes: 41.6" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 126.1;hTERT-RPE1: 110.6;U-937: 106.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014432 Enhanced "Intracellular and membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 32: U-937 - Innate immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA014432: AB_1854146" "unprognostic (1.40e-2)" "prognostic unfavorable (3.84e-4)" "unprognostic (2.86e-3)" "unprognostic (1.94e-1)" "unprognostic (2.74e-2)" "unprognostic (1.74e-2)" "unprognostic (2.63e-2)" "unprognostic (1.23e-1)" "unprognostic (1.84e-2)" "unprognostic (5.33e-2)" "unprognostic (8.28e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (8.85e-8)" "unprognostic (3.29e-3)" "unprognostic (7.80e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (2.17e-4)" 44.9 10.7 12.9 20.9 13.6 21.2 26.3 12.5 12.8 29.5 18.8 108.0 11.9 85.8 20.1 63.0 41.4 33.2 90.8 11.9 18.3 10.1 3.8 30.6 5.7 15.9 15.2 16.9 5.8 3.2 6.8 25.2 13.8 52.7 27.8 12.5 10.8 103.0 104.0 9.7 25.6 123.9 14.6 13.6 36.2 5.8 18.2 4.1 14.5 69.2 3.9 60.9 23.7 11.8 8.8 19.2 16.4 75.9 71.6 63.0 0.5 87.0 92.9 33.2 19.8 0.7 1.0 0.0 18.3 126.1 10.5 1.9 7.7 22.1 30.0 0.2 15.9 0.0 16.7 0.9 46.6 47.1 0.3 33.4 11.9 28.1 39.0 110.6 68.2 0.1 0.3 0.3 76.8 2.9 0.0 11.0 5.4 0.2 10.4 0.2 22.0 0.5 7.5 1.0 0.4 7.9 30.0 1.8 21.9 16.8 14.1 44.5 78.9 42.3 22.8 19.5 34.2 8.0 6.7 0.2 11.5 106.7 26.9 15.0 0.6 41.6 0.2 0.9 0.1 0.1 0.1 0.1 0.2 0.3 0.2 0.2 6.8 8.3 0.4 10.8 0.1 1.4 12.9 13.6 12.5 12.8 11.9 18.3 15.9 15.2 13.8 14.6 18.2 11.8 55.3 12.8 3.4 76.7 0.8 6.4 16.4 11.4 4.0 22.7 2.2 45.3 2801.7 4.3 1.2 3.7 0.0 0.4 8.3 0.0 0.0 9.3 5.7 0.9 16.7 154.2 0.0 17.4 37.1 1.0 0.4 108.8 1.1 0.4 2.5 7.4 28.2 0.2 0.5 21.9 56.6 0.0 0.0 0.0 13.7 2.2 12.5 4.0 10.6 62.8 1.6 44.4 2.1 37.7 1.4 1.6 0.0 116.6 0.3 14.8 0.0 0.4 6.8 10.6 105.2 37.7 218.7 4.2 4.7 0.8 4.5 0.7 2.4 10.3 0.0 2.9 MYH10 NMMHCB ENSG00000133026 "Myosin heavy chain 10" P35580 17 8474207-8630761 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 171.9;Excitatory neurons: 221.3;Inhibitory neurons: 151.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 216.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017180, HPA047541, HPA057198" Enhanced Supported "Actin filaments,Mitochondria,Cytosol" NA NA 28000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" "Actin filaments" "Mitochondria, Cytosol" "CAB017180: , HPA047541: AB_2680081, HPA057198: AB_2683364" "unprognostic (4.67e-2)" "unprognostic (9.64e-3)" "unprognostic (1.13e-1)" "unprognostic (2.52e-3)" "unprognostic (2.40e-1)" "unprognostic (2.33e-2)" "unprognostic (2.75e-1)" "unprognostic (6.45e-2)" "unprognostic (4.77e-2)" "unprognostic (1.11e-1)" "unprognostic (1.39e-3)" "unprognostic (1.69e-2)" "prognostic favorable (1.38e-4)" "unprognostic (2.02e-2)" "unprognostic (2.73e-1)" "unprognostic (5.58e-2)" "prognostic unfavorable (6.42e-4)" 27.3 16.9 12.6 6.1 18.9 13.4 14.7 7.0 29.0 19.6 12.6 12.2 2.3 27.8 16.8 6.6 25.2 26.1 38.9 17.9 8.0 32.5 18.9 66.9 6.5 9.6 7.3 25.9 9.8 13.8 17.7 53.4 9.6 17.7 3.8 22.5 6.6 26.6 4.9 7.9 5.8 22.1 0.5 4.6 9.5 7.4 11.0 5.8 13.6 8.2 4.0 10.5 10.3 13.2 54.1 35.1 216.3 72.7 27.7 33.1 97.1 44.2 39.7 52.2 55.8 94.5 8.0 0.5 28.6 43.9 28.4 5.2 108.7 53.0 58.1 1.2 88.3 62.3 21.7 83.0 64.7 5.4 4.2 47.3 18.9 67.7 26.1 32.1 85.3 70.9 88.1 0.2 32.9 21.6 67.2 1.7 102.1 3.6 7.7 105.9 64.2 0.2 59.1 22.3 17.7 96.8 69.2 3.4 68.1 165.0 18.3 3.6 2.8 48.7 35.6 0.3 38.5 8.3 10.8 13.4 0.3 5.0 111.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 12.6 18.9 7.0 29.0 17.9 8.0 9.6 7.3 9.6 0.5 11.0 13.2 43.0 22.4 14.1 43.1 1.1 4.7 9.5 11.2 9.6 37.1 18.7 16.4 33.5 12.8 11.5 101.2 50.1 171.9 1.0 0.8 17.6 13.7 49.1 28.1 37.6 30.6 2.4 43.5 221.3 1.7 88.6 58.0 3.1 28.5 1.3 41.6 55.6 15.3 15.8 35.3 151.1 1.9 6.1 2.7 3.7 28.6 3.7 1.3 1.8 15.9 0.7 25.9 2.1 96.5 15.5 1.9 0.7 39.9 0.6 7.6 0.0 14.0 21.7 39.4 0.0 12.4 23.6 15.6 27.8 9.5 4.0 76.5 2.0 28.0 2.2 4.4 NAALAD2 "GCPIII, NAALADASE2" ENSG00000077616 "N-acetylated alpha-linked acidic dipeptidase 2" Q9Y3Q0 11 90131515-90192894 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Dipeptidase, Hydrolase, Metalloprotease, Multifunctional enzyme, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 19.9;testis: 13.9" "Group enriched" "Detected in many" 4 "Early spermatids: 39.7;Excitatory neurons: 109.3;Horizontal cells: 70.7;Inhibitory neurons: 110.2;Oligodendrocyte precursor cells: 153.8;Oligodendrocytes: 83.7" "Cancer enhanced" "Detected in some" "testis cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 19.2;SH-SY5Y: 6.1;SuSa: 4.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA060820, HPA065419" Approved Approved Nucleoplasm NA NA "Cluster 43: Testis - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA060820: AB_2684373, HPA065419: AB_2685487" "unprognostic (1.68e-1)" "unprognostic (2.66e-3)" "unprognostic (1.49e-1)" "unprognostic (4.52e-3)" "unprognostic (4.73e-3)" "unprognostic (2.97e-1)" "unprognostic (3.82e-3)" "unprognostic (1.77e-2)" "unprognostic (2.44e-1)" "unprognostic (2.30e-1)" "unprognostic (3.30e-2)" "unprognostic (8.00e-2)" "unprognostic (9.97e-4)" "unprognostic (1.52e-2)" "unprognostic (2.54e-1)" "unprognostic (1.63e-2)" "unprognostic (2.93e-1)" 3.8 10.0 2.3 0.4 3.3 0.1 3.3 1.5 5.3 10.3 0.0 1.9 0.2 4.1 1.9 0.8 3.4 1.2 2.1 2.4 2.8 1.5 0.9 2.1 0.4 3.6 3.5 7.4 0.7 0.1 19.9 3.5 3.4 3.2 0.6 3.5 1.1 1.2 1.1 0.7 1.3 1.1 2.0 2.6 1.2 13.9 3.0 0.1 1.4 0.7 0.1 2.2 4.0 4.2 0.1 0.2 1.8 0.1 0.5 0.1 2.2 0.1 0.1 0.1 0.0 19.2 0.7 0.3 0.2 0.0 0.3 0.3 1.3 0.0 0.0 0.0 0.3 1.9 0.4 1.7 0.2 0.1 0.1 1.9 0.0 0.0 0.0 0.5 0.4 0.2 0.1 0.0 0.0 0.0 0.3 0.3 1.8 0.5 0.2 0.3 0.0 0.2 0.0 0.0 0.2 6.1 0.0 0.2 0.0 4.3 0.2 0.4 2.4 0.1 1.4 0.3 0.3 1.0 0.3 0.3 0.6 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.3 3.3 1.5 5.3 2.4 2.8 3.6 3.5 3.4 2.0 3.0 4.2 2.6 0.0 0.0 3.3 0.1 0.3 0.1 0.0 0.0 17.3 0.0 0.0 2.4 1.5 0.6 0.0 0.0 1.2 0.1 0.0 0.0 0.1 39.7 0.8 13.7 1.2 0.0 0.0 109.3 0.0 0.6 7.5 1.1 0.6 0.0 1.7 0.7 0.2 0.3 70.7 110.2 0.0 0.0 7.2 0.4 17.7 11.1 0.5 0.0 12.2 0.0 8.4 0.0 153.8 83.7 0.0 0.0 14.7 0.4 0.4 0.0 0.1 0.0 2.4 0.0 6.4 4.6 0.6 11.3 0.4 0.0 0.8 0.2 19.4 0.2 0.1 NALCN "bA430M15.1, CanIon, VGCNL1" ENSG00000102452 "Sodium leak channel, non-selective" Q8IZF0 13 101053776-101416508 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.1" "Group enriched" "Detected in some" 10 "Astrocytes: 125.4;Excitatory neurons: 265.8;Inhibitory neurons: 277.4;Oligodendrocyte precursor cells: 324.7;Oligodendrocytes: 477.4" "Cancer enhanced" "Detected in some" "glioma: 1.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 2.6" "Lineage enriched" "Detected in single" 7 "granulocytes: 2.6" "Cell line enhanced" "Detected in many" "HaCaT: 14.2;HHSteC: 14.4;hTERT-RPE1: 11.0;TIME: 19.8;U-87 MG: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031889, HPA031890, HPA031958" Approved NA NA "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA031889: AB_10669638, HPA031890: AB_10696056, HPA031958: AB_10601039" "unprognostic (4.66e-1)" "unprognostic (6.55e-3)" "unprognostic (1.86e-3)" "unprognostic (6.78e-3)" "unprognostic (1.16e-1)" "unprognostic (1.37e-3)" "unprognostic (8.11e-2)" "unprognostic (2.60e-1)" "unprognostic (7.72e-2)" "unprognostic (5.92e-2)" "unprognostic (1.25e-1)" "unprognostic (2.18e-1)" "unprognostic (1.58e-5)" "unprognostic (1.77e-3)" "unprognostic (5.44e-2)" "unprognostic (4.56e-2)" "unprognostic (1.92e-2)" 0.5 4.3 7.5 0.4 9.8 0.6 2.7 6.4 10.3 1.5 0.0 0.4 0.6 0.5 1.5 0.2 1.0 2.3 3.3 8.6 10.2 0.3 1.2 1.1 0.3 8.2 5.8 2.8 1.3 2.9 6.8 3.0 7.0 0.3 0.6 6.1 0.8 1.0 0.3 0.5 0.5 0.5 6.8 0.4 0.7 0.6 8.3 0.0 2.4 0.2 0.1 0.5 0.2 13.1 0.1 7.8 1.4 0.2 0.7 0.3 0.1 0.8 0.8 1.8 0.4 0.2 8.9 0.0 0.3 3.6 0.8 14.2 0.0 2.2 5.5 0.0 1.2 0.4 3.8 0.1 14.4 0.2 0.3 0.4 0.5 1.7 4.6 11.0 8.2 0.1 0.1 0.4 5.9 0.0 0.1 0.0 0.4 1.3 1.8 0.0 0.0 0.0 4.6 1.9 1.2 0.6 0.1 0.0 0.8 0.9 0.2 0.1 19.8 0.4 0.1 0.3 1.8 0.1 0.1 0.1 11.4 0.1 0.3 2.6 0.1 0.2 0.3 0.0 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.1 0.5 0.2 0.1 0.2 0.1 0.1 7.5 9.8 6.4 10.3 8.6 10.2 8.2 5.8 7.0 6.8 8.3 13.1 0.1 0.0 0.0 125.4 0.0 0.3 0.0 0.3 0.6 15.4 3.5 4.6 6.2 0.0 0.1 0.0 6.2 1.0 0.0 0.0 0.0 0.8 4.5 0.1 0.2 0.6 0.0 0.0 265.8 0.2 0.2 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 26.9 277.4 0.0 0.0 0.0 0.0 0.9 0.3 0.1 0.0 23.4 0.0 2.0 0.0 324.7 477.4 0.3 0.0 1.9 0.0 0.0 0.0 0.1 0.0 2.6 0.0 3.6 0.5 0.2 0.8 0.0 0.1 0.5 0.0 0.1 0.0 0.0 NAV3 "KIAA0938, POMFIL1" ENSG00000067798 "Neuron navigator 3" Q8IVL0 12 77324641-78213010 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.3;ovary: 18.3" "Group enriched" "Detected in many" 6 "Astrocytes: 882.1;Excitatory neurons: 1473.6;Inhibitory neurons: 753.8;Microglial cells: 534.0;Oligodendrocyte precursor cells: 786.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "amygdala: 9.7;basal ganglia: 15.0;cerebral cortex: 17.3;hippocampal formation: 13.6;white matter: 10.3" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 1.0" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 47.0;THP-1: 41.8;U-138 MG: 30.8;WM-115: 38.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032111, HPA061392" Approved Approved "Nuclear membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear membrane" Cytosol "HPA032111: AB_10603881, HPA061392: " "unprognostic (3.51e-1)" "unprognostic (6.72e-2)" "unprognostic (1.09e-2)" "unprognostic (1.79e-1)" "unprognostic (8.98e-2)" "unprognostic (2.14e-1)" "unprognostic (2.78e-1)" "unprognostic (3.25e-2)" "unprognostic (3.03e-2)" "unprognostic (2.06e-2)" "unprognostic (2.99e-1)" "unprognostic (1.90e-1)" "unprognostic (5.68e-7)" "unprognostic (6.86e-3)" "unprognostic (1.23e-1)" "unprognostic (1.58e-2)" "unprognostic (2.29e-3)" 3.8 4.8 9.7 1.0 15.0 0.5 4.0 0.9 17.3 1.2 0.0 1.7 0.3 2.0 2.9 1.9 2.2 5.1 1.9 13.6 0.0 0.4 1.0 3.3 0.6 0.7 0.4 18.3 0.5 0.4 3.1 2.2 0.0 2.1 0.8 5.2 0.9 2.5 1.3 2.6 0.6 2.5 1.4 8.0 0.8 2.8 1.6 1.9 1.2 3.4 0.4 3.3 1.7 10.3 3.5 8.7 0.6 0.2 8.5 18.1 0.3 26.5 20.9 10.7 5.3 1.7 0.6 0.2 1.9 22.0 7.2 2.5 7.8 4.0 19.3 0.1 0.2 0.2 3.9 0.2 6.7 0.1 0.2 6.2 0.2 47.0 11.1 9.3 16.4 0.1 0.0 0.1 26.2 0.5 0.2 12.0 2.7 0.3 2.1 1.0 2.1 0.0 1.7 0.1 0.6 0.0 1.6 0.3 3.5 0.8 0.1 41.8 14.1 30.8 8.1 12.0 18.2 1.2 0.0 0.7 8.8 0.5 38.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 9.7 15.0 0.9 17.3 13.6 0.0 0.7 0.4 0.0 1.4 1.6 10.3 11.1 19.2 10.0 882.1 0.0 3.6 8.4 0.2 0.0 5.0 3.8 3.8 3.4 0.0 7.5 0.0 0.0 0.1 0.0 0.2 0.0 4.2 10.4 4.2 8.2 5.6 16.4 0.0 1473.6 1.6 0.1 18.7 0.5 10.3 11.4 0.8 3.9 0.0 7.3 50.5 753.8 0.0 0.0 0.0 3.7 4.7 23.9 1.4 12.4 534.0 0.1 18.3 0.0 786.1 144.1 19.2 0.0 7.5 1.2 18.0 0.0 0.3 8.7 2.0 0.0 28.8 5.3 0.3 0.8 0.2 1.4 0.3 1.3 73.7 0.0 2.9 NBEA "BCL8B, FLJ10197, KIAA1544, LYST2" ENSG00000172915 Neurobeachin Q8NFP9 13 34942270-35673022 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 23.5;retina: 65.7" "Group enriched" "Detected in many" 4 "Excitatory neurons: 1016.1;Inhibitory neurons: 953.0;Oligodendrocyte precursor cells: 466.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 33.1;SH-SY5Y: 80.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039730, HPA040385" Enhanced Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "Nucleoplasm, Nucleoli, Cytosol" "HPA039730: AB_10794202, HPA040385: AB_10795523" "unprognostic (1.80e-2)" "unprognostic (2.90e-1)" "unprognostic (4.99e-2)" "unprognostic (3.89e-4)" "unprognostic (3.59e-1)" "unprognostic (2.04e-1)" "unprognostic (8.75e-2)" "unprognostic (6.95e-3)" "unprognostic (5.01e-1)" "unprognostic (7.43e-2)" "unprognostic (1.03e-3)" "unprognostic (2.45e-1)" "prognostic favorable (7.86e-8)" "unprognostic (2.28e-2)" "unprognostic (9.35e-2)" "unprognostic (1.17e-1)" "unprognostic (6.46e-2)" 2.4 7.2 7.7 1.5 10.7 0.3 4.9 19.0 23.5 3.5 2.8 5.8 1.4 6.1 2.2 3.3 5.5 3.4 6.9 17.4 2.8 4.1 0.6 2.0 1.6 4.1 0.1 6.2 3.1 7.1 8.3 0.6 4.8 6.6 2.5 65.7 4.7 8.4 5.6 1.5 2.5 6.5 0.4 3.2 2.7 3.5 0.0 5.6 6.3 5.7 1.2 3.6 2.8 4.5 0.0 4.5 10.9 6.1 0.7 0.1 0.3 7.0 10.8 7.9 6.6 0.1 1.0 3.0 0.0 12.9 4.7 0.3 3.7 1.5 16.3 1.4 3.6 0.0 3.4 1.2 0.5 1.9 4.7 2.1 1.2 0.1 0.7 33.1 1.8 1.2 0.1 17.6 1.1 1.9 1.1 0.0 4.6 6.2 2.0 1.1 4.7 0.9 9.3 2.1 6.2 80.1 5.4 0.1 3.6 8.1 2.0 0.4 0.1 2.0 1.2 0.0 1.6 1.9 0.5 1.3 5.4 0.6 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 7.7 10.7 19.0 23.5 17.4 2.8 4.1 0.1 4.8 0.4 0.0 4.5 19.7 28.9 9.2 132.9 5.2 1.0 5.3 2.7 1.2 124.8 5.0 6.5 51.8 11.5 14.1 9.2 146.0 0.1 4.4 0.3 1.9 9.2 19.3 5.6 18.4 10.1 22.9 0.8 1016.1 1.8 0.1 12.3 2.0 0.6 25.2 20.7 11.0 0.3 0.9 47.1 953.0 2.1 6.1 3.5 3.9 13.6 17.7 3.5 7.2 150.9 1.2 69.1 0.0 466.9 163.7 2.3 0.1 19.2 5.8 8.5 0.2 7.6 56.5 87.0 6.6 22.2 13.1 8.5 8.0 0.3 0.9 0.0 1.2 11.9 1.1 13.5 NDN "HsT16328, PWCR" ENSG00000182636 "Necdin, MAGE family member" Q99608 15 23685400-23687305 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Growth regulation, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 236.4;Peritubular cells: 207.6;Theca cells: 121.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.5" "Cell line enhanced" "Detected in many" "AF22: 55.0;ASC diff: 52.9;HSkMC: 71.3;NTERA-2: 44.0;SuSa: 57.4;U-2 OS: 80.4;U-266/70: 51.7;U-266/84: 51.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074457 Approved Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA074457: AB_2686691" "unprognostic (3.49e-1)" "unprognostic (1.65e-1)" "unprognostic (4.20e-1)" "unprognostic (2.19e-2)" "unprognostic (2.71e-1)" "unprognostic (9.04e-2)" "unprognostic (6.79e-2)" "unprognostic (3.51e-1)" "unprognostic (3.11e-2)" "unprognostic (1.57e-1)" "unprognostic (1.03e-2)" "unprognostic (4.05e-2)" "prognostic unfavorable (4.52e-4)" "unprognostic (1.89e-2)" "unprognostic (8.10e-2)" "unprognostic (1.96e-1)" "unprognostic (6.81e-2)" 46.8 49.4 43.3 11.1 40.5 1.2 35.1 26.0 39.7 70.5 30.4 35.9 11.1 63.7 24.0 16.8 47.2 23.8 34.6 36.7 89.6 13.0 4.5 19.6 10.9 36.0 41.3 69.8 11.8 8.7 56.3 32.6 46.2 27.3 10.7 20.8 12.7 39.3 14.7 11.9 20.8 33.5 36.7 19.1 20.3 18.5 69.6 6.8 17.4 22.4 6.6 31.4 40.4 32.3 0.1 0.0 55.0 0.0 52.9 20.1 0.1 35.4 0.0 0.8 9.6 0.0 0.0 0.0 0.1 10.6 8.2 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 13.3 0.0 31.8 71.3 0.0 10.2 0.0 0.0 0.0 21.7 1.2 0.0 18.0 0.0 27.6 0.1 44.0 0.0 0.0 0.0 0.0 0.1 3.8 0.0 0.1 0.4 0.0 0.4 0.0 57.4 9.4 0.0 0.0 2.6 80.4 0.0 0.1 51.7 51.7 0.0 5.5 0.0 0.4 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.2 1.5 0.0 0.0 43.3 40.5 26.0 39.7 36.7 89.6 36.0 41.3 46.2 36.7 69.6 32.3 24.1 25.6 11.0 6.8 0.3 13.0 13.8 0.3 27.9 66.0 2.3 19.8 36.8 15.7 1.4 12.9 20.9 1.9 2.9 18.5 23.5 17.9 2.5 1.4 60.8 18.7 6.7 4.2 7.8 10.7 1.4 103.1 4.1 1.1 0.0 83.9 38.9 0.2 7.3 50.5 21.8 4.3 0.0 7.6 13.3 8.6 236.4 2.8 39.2 9.4 0.7 88.7 0.0 9.5 16.4 4.5 2.6 207.6 0.0 6.9 8.1 1.1 4.1 51.0 98.6 91.4 94.0 28.5 21.8 13.4 8.2 2.5 1.4 121.8 7.1 4.1 NEXN "NELIN, nexilin" ENSG00000162614 "Nexilin F-actin binding protein" Q0ZGT2 1 77888513-77943895 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 404.8;skeletal muscle: 676.9;tongue: 548.9" "Cell type enriched" "Detected in many" 6 "Cardiomyocytes: 2329.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 152.2;LHCN-M2: 135.1;RH-30: 108.5" "Region enhanced" "Detected in all" "basal ganglia: 40.4" "Group enriched" "Detected in all" 4 "basal ganglia: 9.0;midbrain: 13.4;pons: 10.0;thalamus: 25.2" "HPA011185, HPA011904" Approved Supported "Plasma membrane,Actin filaments" NA NA 2900000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Actin filaments" "HPA011185: AB_1854409, HPA011904: " "unprognostic (9.73e-2)" "unprognostic (6.72e-2)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.72e-2)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (1.62e-2)" "unprognostic (1.09e-1)" "unprognostic (3.03e-2)" "unprognostic (2.22e-1)" "unprognostic (1.46e-1)" "unprognostic (3.25e-1)" "unprognostic (5.41e-2)" "unprognostic (5.60e-2)" "unprognostic (2.48e-1)" "unprognostic (9.65e-3)" "unprognostic (3.68e-2)" 42.8 22.3 2.3 24.5 3.1 0.6 16.2 1.7 1.6 21.9 2.5 89.2 10.2 79.0 10.7 49.4 47.5 28.7 404.8 1.3 1.8 8.0 5.6 25.2 5.6 1.4 3.3 15.2 10.0 1.5 1.4 10.6 1.5 62.5 15.7 0.6 11.5 69.8 676.9 6.8 26.7 70.6 1.2 8.6 44.1 5.7 4.7 2.1 10.3 548.9 1.8 49.7 19.5 1.7 26.0 1.5 4.5 0.2 79.5 75.3 12.3 152.2 65.5 29.8 20.2 4.6 0.2 0.0 8.6 54.7 34.4 3.4 3.3 14.3 53.3 0.7 3.4 6.2 7.5 1.5 59.3 1.3 0.2 56.6 3.3 40.7 23.8 65.2 22.8 6.0 0.3 0.0 135.1 0.0 29.9 1.8 23.8 0.0 18.6 24.3 108.5 0.2 35.5 1.2 0.1 1.1 13.3 0.0 1.0 29.9 0.0 3.5 23.4 71.7 53.6 31.2 76.1 0.2 0.2 0.1 4.0 2.8 0.2 0.0 1.7 0.0 0.2 1.0 0.0 0.7 0.1 0.2 0.9 0.5 0.3 0.1 1.4 0.3 0.8 0.6 0.0 3.6 2.3 3.1 1.7 1.6 1.3 1.8 1.4 3.3 1.5 1.2 4.7 1.7 8.3 105.8 4.9 11.4 2.1 1.8 0.9 4.6 1.2 2.7 1.4 33.1 2329.6 0.0 5.4 0.0 4.2 0.8 4.1 0.4 1.9 15.3 24.0 2.6 24.2 17.4 0.0 1.7 26.6 32.4 4.0 93.2 1.1 3.2 1.3 29.7 38.6 1.5 1.2 1.7 27.6 0.5 0.0 4.4 2.2 9.0 73.3 44.9 0.0 16.9 5.8 0.7 0.0 24.6 27.3 21.8 0.1 346.1 0.3 1.3 5.3 0.7 0.4 3.8 216.9 70.4 177.2 0.7 3.6 0.8 0.9 0.3 2.3 13.0 2.1 0.4 NFASC "FLJ46866, KIAA0756, NF, NRCAML" ENSG00000163531 Neurofascin O94856 1 204828651-205022822 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 151.0;Excitatory neurons: 148.4;Horizontal cells: 220.4;Inhibitory neurons: 139.0;Oligodendrocyte precursor cells: 87.9;Oligodendrocytes: 226.6;Rod photoreceptor cells: 195.5" "Cancer enriched" "Detected in many" 5 "glioma: 8.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 27.6;fHDF/TERT166: 50.3;hTERT-RPE1: 24.0;SCLC-21H: 22.8;U-138 MG: 62.7;U-87 MG: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008832 Enhanced NA NA 2200000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "HPA008832: AB_1854411" "unprognostic (1.71e-1)" "unprognostic (1.07e-1)" "unprognostic (2.62e-1)" "unprognostic (3.39e-2)" "unprognostic (6.65e-2)" "unprognostic (1.18e-2)" "unprognostic (3.71e-3)" "unprognostic (3.37e-1)" "unprognostic (6.34e-3)" "unprognostic (2.79e-1)" "prognostic favorable (3.21e-5)" "unprognostic (3.76e-1)" "prognostic unfavorable (2.93e-5)" "unprognostic (1.56e-3)" "unprognostic (1.91e-1)" "unprognostic (6.90e-2)" "unprognostic (5.26e-3)" 5.2 7.5 7.8 3.7 31.5 0.1 3.2 8.4 15.2 5.0 0.0 8.6 4.5 8.3 9.0 10.0 12.1 5.9 15.3 10.7 5.6 9.8 1.9 5.0 2.3 13.1 14.1 10.1 5.9 1.0 5.6 10.6 7.8 7.5 5.9 22.6 2.1 16.3 3.0 4.3 5.0 14.2 3.9 6.5 4.4 1.5 35.6 0.6 2.9 3.8 2.9 9.4 7.7 50.1 0.0 0.1 3.1 0.1 0.4 1.0 0.1 27.6 0.0 19.9 5.9 0.2 0.1 0.0 0.1 50.3 18.5 13.4 0.6 0.8 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.1 12.7 0.7 24.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 7.0 0.9 0.3 0.0 2.3 0.0 0.0 0.0 22.8 1.3 0.0 1.5 0.0 2.0 0.3 0.0 0.0 62.7 13.5 0.1 0.0 0.0 0.0 0.0 31.3 0.0 16.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 31.5 8.4 15.2 10.7 5.6 13.1 14.1 7.8 3.9 35.6 50.1 2.5 0.0 0.6 64.3 0.0 2.2 1.5 1.9 0.6 151.0 1.7 10.5 23.9 1.5 1.5 0.0 12.5 0.5 0.0 0.3 0.0 0.2 7.3 0.5 0.4 7.6 37.8 0.0 148.4 0.0 0.5 14.2 1.1 0.1 0.0 0.1 3.3 1.7 0.4 220.4 139.0 6.0 0.0 0.6 1.9 17.9 6.5 0.4 1.8 15.0 0.0 14.2 0.0 87.9 226.6 0.5 0.5 5.7 0.0 1.1 0.0 1.5 5.9 195.5 52.6 2.3 49.9 1.7 3.9 5.5 4.7 0.7 0.3 0.7 1.0 0.8 NLGN4X "HLNX, KIAA1260, NLGN, NLGN4" ENSG00000146938 "Neuroligin 4 X-linked" Q8N0W4 X 5840637-6228867 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Asperger syndrome, Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.5;lymphoid tissue: 14.3" "Cell type enhanced" "Detected in many" "Astrocytes: 113.9;Excitatory neurons: 162.2;Inhibitory neurons: 236.8;Oligodendrocyte precursor cells: 702.7" "Group enriched" "Detected in many" 4 "endometrial cancer: 2.7;glioma: 8.5;testis cancer: 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 55.6;NTERA-2: 44.1;SuSa: 42.7" HPA001651 Approved NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "HPA001651: AB_1079470" "unprognostic (2.21e-1)" "unprognostic (4.01e-2)" "unprognostic (1.11e-1)" "unprognostic (8.57e-2)" "unprognostic (1.28e-1)" "unprognostic (1.52e-1)" "unprognostic (1.36e-1)" "unprognostic (1.04e-1)" "unprognostic (1.67e-1)" "unprognostic (9.49e-2)" "unprognostic (1.48e-2)" "unprognostic (9.32e-2)" "unprognostic (5.10e-3)" "unprognostic (7.16e-4)" "unprognostic (6.70e-2)" "unprognostic (2.98e-2)" "unprognostic (1.10e-2)" 3.4 1.3 8.8 1.8 10.1 0.0 2.2 9.8 12.7 5.1 0.0 3.4 1.3 2.3 0.4 0.7 2.0 2.5 4.5 14.8 28.5 0.3 1.3 1.1 0.8 6.5 5.6 11.6 0.4 5.2 1.7 3.6 4.4 1.1 1.9 9.2 0.8 1.9 0.3 0.6 2.6 3.7 1.6 2.2 1.1 2.6 8.9 14.3 0.7 0.2 0.5 2.1 1.4 4.2 0.0 0.0 55.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 7.4 0.0 44.1 0.0 0.1 0.0 0.0 0.1 4.1 11.5 2.7 3.5 0.0 0.1 0.0 42.7 5.7 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 10.1 9.8 12.7 14.8 28.5 6.5 5.6 4.4 1.6 8.9 4.2 12.1 0.0 0.5 113.9 0.3 0.3 0.1 0.2 0.0 15.0 5.2 3.4 2.8 0.0 0.1 0.0 25.0 3.7 0.1 0.0 0.0 0.0 0.1 19.7 69.5 2.5 0.0 0.0 162.2 0.0 2.4 9.6 0.0 33.2 0.0 2.2 1.8 0.0 0.6 0.0 236.8 0.0 0.0 0.3 0.5 0.7 18.0 0.3 14.2 4.7 0.0 12.5 0.0 702.7 68.3 0.0 0.0 29.7 0.1 0.0 0.0 0.1 0.7 3.3 13.1 18.4 5.0 2.0 5.5 0.2 0.6 3.6 0.5 8.8 0.0 0.3 NPNT "EGFL6L, POEM" ENSG00000168743 Nephronectin Q6UXI9 4 105894775-106004027 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 137.0;thyroid gland: 234.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 185.9;Alveolar cells type 2: 103.7;Club cells: 56.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 104.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 30.9;CAPAN-2: 19.1;HeLa: 32.3;Hep G2: 27.1;MCF7: 24.3;RPTEC TERT1: 37.7;T-47d: 51.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003711, HPA050203" Supported Approved "Nucleoplasm,Cell Junctions,Cytosol" "Secreted to extracellular matrix" NA NA 120000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Cell Junctions, Cytosol" "HPA003711: AB_1854591, HPA050203: AB_2681050" "unprognostic (1.24e-1)" "unprognostic (7.93e-2)" "unprognostic (1.59e-1)" "unprognostic (2.43e-2)" "unprognostic (3.92e-1)" "unprognostic (2.49e-1)" "unprognostic (1.87e-1)" "unprognostic (7.85e-3)" "unprognostic (4.78e-4)" "unprognostic (1.19e-2)" "unprognostic (1.57e-1)" "unprognostic (1.68e-1)" "prognostic favorable (8.28e-8)" "unprognostic (4.81e-2)" "unprognostic (1.21e-1)" "unprognostic (1.77e-1)" "unprognostic (2.31e-2)" 22.8 6.3 9.7 5.6 7.9 0.2 27.0 4.7 8.0 32.4 5.7 24.5 56.1 20.9 22.2 10.9 22.4 30.5 5.2 7.5 14.6 105.0 4.0 137.0 4.5 6.1 31.8 10.9 40.1 1.0 47.4 3.4 9.2 82.9 25.2 2.4 8.9 18.7 4.9 8.2 74.1 14.1 4.4 14.8 14.9 3.1 10.5 14.2 234.5 11.5 5.4 9.7 22.1 6.6 0.0 0.2 0.3 0.6 0.0 0.0 30.9 0.2 0.1 0.0 0.0 14.9 19.1 0.2 0.8 0.2 0.0 1.7 7.4 0.0 0.0 0.0 8.4 0.8 32.3 27.1 0.1 0.0 0.2 3.2 2.4 0.0 0.0 0.3 0.0 0.4 0.1 0.4 0.0 24.3 0.4 1.5 0.3 0.1 12.0 0.0 0.1 0.3 37.7 1.6 1.7 0.6 1.8 14.1 0.0 4.1 51.2 1.3 0.0 0.6 0.4 0.5 1.1 0.3 1.1 0.0 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 7.9 4.7 8.0 7.5 14.6 6.1 31.8 9.2 4.4 10.5 6.6 5.2 185.9 103.7 15.3 0.0 1.9 5.2 13.1 1.8 1.1 22.2 7.0 2.5 27.1 56.4 33.1 0.0 2.4 0.7 5.9 1.9 24.7 11.0 1.0 1.5 18.4 15.6 0.0 1.0 2.5 0.2 8.3 1.1 1.9 0.0 3.3 2.9 0.3 0.3 0.0 10.0 10.6 4.1 0.0 1.5 15.4 2.5 0.6 5.4 14.0 0.0 0.0 0.0 2.0 0.3 7.5 3.4 0.0 0.0 28.4 19.6 4.3 6.4 0.2 0.0 1.9 26.4 2.4 2.0 3.6 1.1 1.5 0.3 1.5 11.0 5.7 NR2F2 "ARP1, COUP-TFII, COUPTF2, COUPTFB, NF-E3, SVP40, TFCOUP2" ENSG00000185551 "Nuclear receptor subfamily 2 group F member 2" P24468 15 96325938-96340263 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 292.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 542.2;Hepatic stellate cells: 395.5;Leydig cells: 510.4;Peritubular cells: 610.5;Sertoli cells: 486.4;Smooth muscle cells: 385.7;Theca cells: 572.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058974 Approved Nucleoplasm,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "HPA058974: AB_2732629" "unprognostic (9.28e-2)" "unprognostic (2.52e-2)" "unprognostic (2.34e-1)" "unprognostic (1.42e-2)" "unprognostic (8.96e-2)" "unprognostic (5.44e-2)" "unprognostic (3.38e-1)" "unprognostic (1.14e-1)" "unprognostic (2.61e-1)" "unprognostic (1.87e-1)" "unprognostic (1.89e-1)" "unprognostic (9.19e-2)" "unprognostic (5.14e-2)" "unprognostic (5.96e-2)" "unprognostic (1.72e-2)" "unprognostic (7.47e-2)" "unprognostic (1.28e-2)" 95.5 43.1 32.7 18.8 19.2 0.1 59.7 15.0 19.6 128.6 23.5 52.6 21.5 120.9 61.8 22.1 101.5 65.7 44.4 20.0 24.8 79.8 32.1 56.8 42.4 16.2 21.9 292.4 20.0 30.7 20.3 74.7 18.2 60.6 26.7 2.5 22.9 126.4 33.1 24.1 32.1 81.8 12.5 106.2 82.3 26.7 49.3 7.8 46.2 31.5 15.1 46.3 74.5 10.7 154.7 39.1 125.6 78.5 249.1 85.5 41.9 109.1 83.2 111.1 94.3 134.8 153.4 0.1 86.8 55.2 44.1 90.4 22.3 78.3 138.8 0.5 86.5 49.9 48.7 24.6 69.5 38.7 18.0 61.3 26.5 92.5 19.8 130.5 207.3 0.1 135.3 0.4 71.2 105.5 0.1 27.6 1.2 59.6 52.7 0.1 30.9 0.2 244.7 165.7 15.8 0.2 12.3 3.7 17.5 55.0 61.1 2.8 215.3 119.9 39.7 28.3 38.8 0.1 0.4 0.4 67.0 18.9 85.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.7 19.2 15.0 19.6 20.0 24.8 16.2 21.9 18.2 12.5 49.3 10.7 133.4 28.9 18.1 0.7 1.1 14.4 24.9 71.7 39.3 7.5 51.9 50.8 46.4 203.0 34.6 62.5 25.0 126.2 2.0 35.7 46.9 22.0 3.2 70.9 542.2 166.1 26.4 5.3 0.1 10.9 50.3 125.8 80.0 68.9 0.0 41.5 395.5 51.6 10.3 3.3 24.8 35.5 32.6 12.2 20.1 22.9 510.4 5.0 26.6 36.5 0.6 30.2 0.0 0.0 0.5 15.6 23.9 610.5 2.8 22.3 14.3 65.5 37.3 13.8 486.4 27.8 385.7 6.4 7.9 20.5 10.4 35.3 5.8 572.5 27.1 21.3 OBSCN "ARHGEF30, KIAA1556, KIAA1639, UNC89" ENSG00000154358 "Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF" Q5VST9 1 228208044-228378876 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Calmodulin-binding, Developmental protein, Kinase, Muscle protein, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skeletal muscle: 481.3" "Cell type enriched" "Detected in many" 6 "Cardiomyocytes: 155.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 10.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA021186, HPA065801" Enhanced Approved "Plasma membrane,Cytosol" NA NA 4500000 "Cluster 7: Monocytes - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA021186: AB_1854761, HPA065801: " "unprognostic (8.47e-3)" "unprognostic (1.56e-1)" "unprognostic (9.99e-2)" "prognostic unfavorable (1.64e-4)" "unprognostic (5.30e-3)" "unprognostic (6.36e-2)" "unprognostic (4.54e-3)" "unprognostic (1.82e-1)" "unprognostic (8.81e-2)" "unprognostic (1.93e-2)" "unprognostic (3.38e-1)" "unprognostic (1.45e-1)" "unprognostic (1.57e-3)" "unprognostic (1.34e-1)" "unprognostic (1.77e-1)" "unprognostic (3.53e-1)" "unprognostic (1.16e-2)" 3.5 2.5 2.4 1.4 18.4 1.6 3.7 10.4 4.4 8.1 18.1 5.2 0.7 3.7 1.8 4.6 5.1 1.1 78.5 0.9 2.7 6.6 1.3 8.9 2.1 4.3 2.7 8.6 5.4 1.1 13.6 0.9 2.4 9.9 0.5 0.8 9.4 1.7 481.3 4.7 5.4 0.5 1.0 9.3 5.2 1.9 6.3 4.9 7.5 112.8 1.3 3.2 7.4 0.1 1.7 2.8 3.6 3.7 0.2 0.2 4.6 1.6 0.7 1.7 1.4 2.1 1.3 3.2 5.4 0.7 0.7 2.1 1.3 2.2 0.3 2.0 3.4 1.7 10.5 0.1 1.2 2.4 2.2 1.4 0.6 0.4 0.5 5.1 0.5 7.0 3.2 0.0 0.3 1.8 3.3 3.5 4.9 0.6 2.1 4.4 0.0 1.9 1.8 1.4 1.7 6.3 0.6 3.9 1.0 0.8 3.4 4.0 1.0 0.0 5.1 0.3 0.5 2.5 0.5 4.7 0.0 0.8 2.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.1 2.4 18.4 10.4 4.4 0.9 2.7 4.3 2.7 2.4 1.0 6.3 0.1 1.5 0.0 5.5 1.6 2.4 2.2 6.6 7.7 23.9 4.2 7.3 11.9 155.8 4.3 4.5 5.5 10.4 0.1 1.9 0.7 11.7 3.6 4.9 3.9 3.7 3.1 0.0 3.0 3.9 0.5 0.5 5.7 3.1 11.3 7.0 1.8 1.4 0.5 0.1 0.0 5.3 2.7 4.1 0.3 1.0 4.5 3.1 1.1 1.8 5.6 0.5 7.9 4.1 1.5 1.7 0.8 1.1 4.5 1.5 3.8 0.6 4.1 1.3 3.2 0.0 22.9 6.1 1.0 4.1 9.4 1.7 1.2 5.4 6.2 1.2 3.6 OGN "mimecan, OIF, SLRR3A" ENSG00000106809 Osteoglycin P20774 9 92383268-92404696 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.0" "Group enriched" "Detected in many" 8 "Endometrial stromal cells: 104.1;Fibroblasts: 326.2;Leydig cells: 166.2;Peritubular cells: 212.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "T-reg: 1.7" "Lineage enriched" "Detected in single" 9 "T-cells: 1.7" "Group enriched" "Detected in some" 4 "ASC TERT1: 22.2;HSkMC: 9.7;JURKAT: 15.7;MOLT-4: 32.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013132 Approved Supported "Endoplasmic reticulum" "Secreted in other tissues" NA NA 170000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA013132: AB_1854825" "unprognostic (2.31e-1)" "unprognostic (3.94e-3)" "unprognostic (1.74e-1)" "unprognostic (2.08e-2)" "unprognostic (2.60e-1)" "unprognostic (2.70e-1)" "unprognostic (1.44e-4)" "unprognostic (4.42e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (4.04e-4)" "unprognostic (2.47e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.92e-4)" "unprognostic (3.37e-3)" "unprognostic (3.86e-2)" "unprognostic (2.20e-3)" "prognostic unfavorable (2.03e-4)" 100.1 22.5 1.4 6.0 3.0 0.2 53.8 4.7 6.8 216.0 11.0 43.0 10.6 130.5 44.9 30.8 67.1 164.7 79.8 1.7 2.3 6.4 4.1 18.6 2.1 1.8 1.8 91.8 11.1 117.3 19.1 22.7 2.0 57.9 32.2 0.0 3.2 19.3 2.6 3.8 23.6 118.0 2.3 2.4 22.0 13.3 2.2 4.5 14.7 22.0 5.6 54.0 23.3 2.1 0.0 0.0 0.0 0.0 4.4 22.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 9.7 0.0 0.0 0.0 0.0 0.0 15.7 0.0 0.0 0.0 0.1 32.2 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 1.4 3.0 4.7 6.8 1.7 2.3 1.8 1.8 2.0 2.3 2.2 2.1 10.3 6.4 1.5 1.0 0.4 4.2 0.1 0.0 1.2 0.6 0.7 0.4 2.6 10.0 7.4 3.7 0.0 2.0 0.6 0.1 0.0 0.0 1.2 2.9 104.1 5.2 0.0 0.0 1.9 0.0 1.7 326.2 7.7 1.7 1.3 0.0 20.0 0.1 4.6 0.0 1.8 0.0 0.0 0.3 11.1 4.2 166.2 2.3 1.8 16.9 0.2 0.1 0.0 2.0 1.6 0.0 0.0 212.1 0.7 0.4 0.0 0.0 2.9 0.2 6.6 4.7 22.7 0.6 0.6 0.7 4.5 5.7 2.1 1.6 0.0 0.2 OLFML2A FLJ00237 ENSG00000185585 "Olfactomedin like 2A" Q68BL7 9 124777133-124814885 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 40.1;Endothelial cells: 21.2;Fibroblasts: 29.0;Skeletal myocytes: 63.0;Smooth muscle cells: 36.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 160.0;GAMG: 34.0;HeLa: 39.8;hTERT-RPE1: 38.0;WM-115: 64.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021180, HPA022254" Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" NA NA 240000 "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA021180: AB_1854790, HPA022254: AB_1854791" "unprognostic (1.12e-1)" "unprognostic (3.07e-2)" "unprognostic (3.16e-1)" "unprognostic (2.45e-1)" "unprognostic (4.01e-2)" "unprognostic (1.27e-1)" "unprognostic (1.15e-1)" "unprognostic (3.00e-1)" "unprognostic (1.26e-3)" "unprognostic (7.53e-2)" "unprognostic (2.49e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (3.73e-5)" "unprognostic (5.72e-3)" "unprognostic (3.30e-2)" "unprognostic (7.91e-2)" "unprognostic (1.05e-2)" 15.4 2.9 2.6 2.7 3.1 0.3 11.1 2.2 4.6 25.0 3.3 29.9 3.3 25.3 2.8 8.2 6.4 4.8 16.4 2.2 2.4 4.3 0.7 10.5 2.4 2.8 2.1 12.0 4.8 4.6 2.8 7.0 2.8 7.4 6.2 2.2 7.0 12.2 10.8 16.0 6.9 16.0 2.1 32.8 5.5 1.1 2.6 3.1 19.1 10.0 3.7 17.6 14.6 2.1 0.8 14.6 1.2 0.4 16.8 160.0 0.1 1.8 8.2 3.5 3.5 0.2 2.2 0.0 3.4 0.1 34.0 25.5 0.4 0.8 4.0 0.0 0.1 0.0 39.8 0.1 0.9 0.0 0.1 11.3 2.7 10.2 1.4 38.0 0.0 0.0 0.0 0.2 1.8 0.4 0.0 0.3 3.4 0.0 0.9 0.0 9.5 0.0 0.0 1.2 0.0 0.1 2.9 0.2 4.3 28.6 3.9 0.5 0.1 5.2 4.6 5.5 0.7 1.9 0.0 0.1 15.2 0.8 64.1 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.1 2.6 3.1 2.2 4.6 2.2 2.4 2.8 2.1 2.8 2.1 2.6 2.1 40.1 0.0 1.3 0.7 0.4 12.0 5.9 17.5 6.2 0.6 2.9 8.3 13.8 1.5 5.5 0.0 2.1 0.3 0.5 0.0 0.0 0.1 0.7 0.2 1.5 21.2 0.0 0.0 0.4 0.6 0.3 29.0 0.5 0.2 0.0 0.9 3.6 0.1 0.1 0.0 0.6 0.0 4.1 1.5 7.9 1.4 2.8 0.9 10.6 8.4 0.1 0.3 0.0 0.0 0.1 0.0 0.0 1.5 0.1 4.0 0.0 0.1 11.5 4.0 13.1 63.0 36.4 0.4 0.7 4.5 8.4 0.0 0.6 4.2 0.0 3.5 P2RX6 "MGC129625, P2RXL1, P2X6, P2XM" ENSG00000099957 "Purinergic receptor P2X 6" O15547 22 21009808-21028830 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 3.4;skeletal muscle: 12.4;tongue: 7.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.6;Excitatory neurons: 8.9;Inhibitory neurons: 7.9;Ionocytes: 8.2;Skeletal myocytes: 20.8" "Group enriched" "Detected in some" 5 "glioma: 1.0;melanoma: 2.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 9.7;LHCN-M2: 6.7;RH-30: 4.2;U-87 MG: 11.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028776, HPA028777" Approved Approved Nucleoli,Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Nucleoli, Cytosol" "HPA028776: AB_2672771, HPA028777: AB_2672772" "unprognostic (1.81e-2)" "unprognostic (5.15e-3)" "unprognostic (2.11e-2)" "unprognostic (1.12e-1)" "unprognostic (4.28e-2)" "unprognostic (1.79e-5)" "unprognostic (1.70e-2)" "unprognostic (6.20e-2)" "unprognostic (1.49e-1)" "unprognostic (2.59e-2)" "unprognostic (1.89e-2)" "unprognostic (2.45e-2)" "unprognostic (2.88e-10)" "unprognostic (2.81e-1)" "unprognostic (1.38e-1)" "unprognostic (7.33e-2)" "unprognostic (2.39e-3)" 0.3 1.1 0.0 0.3 0.2 0.0 0.1 1.0 2.6 0.1 0.4 0.1 0.0 0.2 0.0 0.2 0.3 0.8 1.3 1.0 1.5 0.2 0.1 0.3 0.2 3.4 0.4 0.3 0.1 0.0 1.3 0.8 3.4 0.3 0.0 0.3 0.2 0.7 12.4 0.1 0.1 0.1 0.1 1.6 0.2 1.1 0.6 0.0 0.0 7.7 0.0 0.2 0.1 1.2 0.0 0.4 0.7 0.2 0.1 0.0 0.8 0.1 1.7 0.7 1.2 0.0 0.0 0.0 1.1 0.4 2.9 1.3 0.0 0.1 0.1 0.2 0.0 1.9 0.9 0.0 2.8 0.0 2.4 0.3 0.0 1.2 0.0 9.7 0.0 0.0 2.1 0.6 6.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 4.2 0.2 0.0 0.0 0.2 3.1 1.2 0.1 0.5 0.1 0.0 0.0 0.0 2.1 0.3 0.0 0.0 0.2 0.0 0.0 11.7 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 2.6 1.0 1.5 3.4 0.4 3.4 0.1 0.6 1.2 0.2 0.0 0.6 0.3 0.1 0.1 0.8 0.8 0.6 7.6 0.0 0.4 2.4 0.0 0.2 1.8 0.0 0.5 0.0 0.1 0.0 0.0 2.2 1.8 0.5 0.2 3.5 2.7 8.9 0.0 0.4 1.4 0.0 0.7 2.5 0.1 1.8 0.1 0.1 1.7 7.9 0.7 8.2 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 1.1 0.0 5.0 3.3 0.0 0.0 0.4 0.1 0.2 0.0 0.3 3.2 1.1 0.0 20.8 0.4 1.6 0.4 0.3 0.1 0.4 0.5 0.1 0.1 0.2 PABPC5 PABP5 ENSG00000174740 "Poly(A) binding protein cytoplasmic 5" Q96DU9 X 91434595-91438584 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 7.4;ovary: 11.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 12.8;Endometrial stromal cells: 8.3;Horizontal cells: 8.4;Oligodendrocyte precursor cells: 7.5;Peritubular cells: 11.7;Sertoli cells: 13.1;Skeletal myocytes: 11.2;Theca cells: 12.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.0;HSkMC: 2.8;LHCN-M2: 1.9;RH-30: 8.4;U-2 OS: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA000164, HPA000165" Approved NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "HPA000164: AB_1079551, HPA000165: AB_1079552" "unprognostic (1.05e-1)" "unprognostic (2.98e-1)" "unprognostic (3.68e-2)" "unprognostic (2.92e-1)" "unprognostic (1.37e-1)" "unprognostic (1.56e-2)" "unprognostic (1.23e-1)" "unprognostic (3.52e-1)" "unprognostic (2.89e-2)" "unprognostic (1.01e-1)" "unprognostic (2.93e-2)" "unprognostic (2.46e-1)" "unprognostic (1.26e-1)" "unprognostic (6.87e-3)" "unprognostic (1.27e-1)" "unprognostic (4.55e-2)" "unprognostic (8.07e-2)" 2.1 7.4 1.1 0.7 1.3 0.0 0.9 1.1 1.5 2.3 0.5 1.5 0.4 3.1 2.5 1.2 1.8 1.3 1.6 1.0 1.4 0.8 0.3 0.9 0.8 1.5 1.3 11.1 0.4 1.2 1.3 0.7 1.4 2.3 0.7 1.2 0.8 2.0 0.5 0.4 0.7 2.9 1.4 1.8 0.7 1.6 1.4 0.2 2.0 0.9 0.5 1.3 1.0 1.7 0.0 0.0 7.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.9 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.3 1.1 1.5 1.0 1.4 1.5 1.3 1.4 1.4 1.4 1.7 1.3 0.0 0.0 0.3 0.0 0.1 0.3 0.0 0.0 12.8 0.1 1.1 0.7 0.0 0.0 1.8 2.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 8.3 1.3 0.0 0.0 1.7 0.0 0.0 5.0 0.0 0.1 0.0 6.6 1.1 0.0 0.1 8.4 1.8 0.0 0.0 0.0 0.4 0.7 5.9 0.1 3.6 1.0 0.0 4.1 0.0 7.5 3.6 0.0 0.0 11.7 0.0 0.3 0.0 0.1 0.0 3.4 13.1 11.2 4.4 0.2 0.3 0.1 0.3 0.0 0.1 12.0 0.0 0.0 PAPLN MGC50452 ENSG00000100767 "Papilin, proteoglycan like sulfated glycoprotein" O95428 14 73237497-73274640 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 119.8;Endometrial stromal cells: 37.9;Leydig cells: 34.5;Peritubular cells: 44.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "neutrophil: 2.5;plasmacytoid DC: 5.4" "Group enriched" "Detected in many" 7 "dendritic cells: 5.4;granulocytes: 2.5" "Cell line enhanced" "Detected in many" "HHSteC: 16.1;HSkMC: 30.6;hTCEpi: 11.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA048682, HPA053453" Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA 76000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA048682: AB_2680492, HPA053453: AB_2682155" "unprognostic (1.97e-3)" "unprognostic (3.27e-2)" "unprognostic (1.88e-1)" "unprognostic (3.56e-3)" "unprognostic (7.42e-2)" "unprognostic (7.91e-3)" "unprognostic (2.01e-2)" "unprognostic (2.46e-3)" "unprognostic (9.13e-3)" "unprognostic (3.69e-2)" "unprognostic (1.41e-1)" "unprognostic (4.87e-2)" "unprognostic (1.89e-2)" "unprognostic (2.14e-2)" "unprognostic (3.05e-3)" "unprognostic (2.69e-2)" "unprognostic (5.58e-2)" 16.1 6.6 15.7 8.4 17.0 2.3 10.7 12.1 23.5 30.3 15.7 13.4 3.0 20.4 14.9 7.1 23.0 5.6 8.0 14.4 13.3 42.6 3.2 13.4 15.2 14.1 14.6 16.8 4.0 0.4 16.4 4.0 13.1 13.6 4.5 9.5 7.5 7.5 2.1 15.7 17.8 6.3 12.3 29.1 11.3 6.4 14.4 5.1 24.8 1.8 13.6 5.1 9.1 12.3 2.7 2.6 1.0 0.4 1.9 2.3 5.8 0.5 0.0 0.1 0.2 3.4 0.8 0.5 2.7 0.0 0.1 4.3 2.7 2.0 0.3 3.0 3.9 1.2 4.7 0.3 16.1 0.4 2.1 30.6 11.4 0.5 1.7 0.2 0.6 2.5 0.8 0.3 0.0 1.4 0.3 3.0 0.6 0.3 0.8 0.4 0.3 2.8 2.3 0.6 0.3 0.5 6.2 7.0 1.3 7.9 0.2 4.8 0.5 0.7 2.3 0.2 0.3 1.3 0.1 0.3 1.4 1.4 0.6 0.8 0.5 0.3 0.2 0.3 0.1 0.4 0.1 0.2 0.1 0.5 0.2 0.2 2.5 0.3 0.2 5.4 0.3 0.1 15.7 17.0 12.1 23.5 14.4 13.3 14.1 14.6 13.1 12.3 14.4 12.3 0.4 0.0 2.6 119.8 0.3 2.0 0.7 5.1 0.6 1.2 1.8 1.4 1.9 7.2 4.8 5.5 8.4 0.5 5.7 0.4 0.0 4.0 0.3 11.8 37.9 3.4 0.0 0.0 0.3 0.0 1.1 8.3 0.5 16.1 0.0 0.2 3.3 0.1 1.2 0.0 0.9 0.4 2.0 0.3 1.6 1.7 34.5 1.8 1.8 10.3 1.6 15.7 0.0 3.0 0.3 0.4 0.0 44.0 0.2 1.4 0.2 10.2 3.7 3.0 6.6 1.4 1.8 0.6 0.1 0.8 3.0 0.4 0.7 0.1 1.0 0.4 PDE5A ENSG00000138735 "Phosphodiesterase 5A" O76074 4 119494397-119628804 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 66.1;Inhibitory neurons: 58.3;Oligodendrocyte precursor cells: 56.8;Peritubular cells: 104.9;Smooth muscle cells: 80.9" "Group enriched" "Detected in all" 4 "prostate cancer: 7.0;thyroid cancer: 27.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 47.5;HHSteC: 65.9;hTERT-RPE1: 24.6" "Region enhanced" "Detected in all" "cerebellum: 18.2" "Low region specificity" "Detected in all" "HPA004729, HPA012873" Approved Approved Cytosol NA NA 850000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA004729: AB_1079588, HPA012873: AB_1855124" "unprognostic (6.95e-2)" "prognostic favorable (5.20e-4)" "unprognostic (1.28e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (7.36e-2)" "unprognostic (2.58e-2)" "unprognostic (2.29e-2)" "unprognostic (6.97e-2)" "unprognostic (2.05e-2)" "unprognostic (2.54e-1)" "unprognostic (2.16e-2)" "unprognostic (1.52e-2)" "unprognostic (8.98e-2)" "unprognostic (8.71e-3)" "prognostic unfavorable (1.17e-4)" 15.4 11.3 0.9 10.9 3.5 2.1 9.6 4.9 3.7 32.7 12.6 37.0 15.5 14.4 41.5 41.3 22.9 10.4 12.8 1.4 3.6 5.9 1.5 22.1 6.4 4.9 8.2 5.4 12.4 8.3 3.5 13.2 5.2 59.8 25.9 9.6 9.8 49.8 6.9 5.0 18.9 11.4 0.0 5.8 9.6 9.4 3.4 3.7 16.8 5.6 3.5 14.6 15.8 1.9 16.7 0.8 11.0 1.2 3.7 5.5 1.9 10.7 47.5 0.5 1.0 1.0 1.3 1.6 0.5 13.4 3.0 5.8 3.5 1.7 1.3 0.4 7.4 18.5 2.6 0.9 65.9 3.9 1.7 6.1 3.3 1.1 0.1 24.6 1.4 3.7 2.0 2.9 1.6 0.9 5.0 0.6 2.3 1.8 2.8 0.7 5.9 4.3 4.1 4.9 4.3 8.8 13.0 15.3 1.3 8.1 2.7 2.1 2.5 6.2 5.2 3.4 1.5 4.1 2.0 1.5 5.9 1.0 0.9 0.0 0.0 0.0 0.1 0.0 0.5 0.4 0.3 0.1 0.0 0.3 0.1 0.2 0.4 0.2 0.1 0.1 0.1 1.2 0.9 3.5 4.9 3.7 1.4 3.6 4.9 8.2 5.2 0.0 3.4 1.9 7.8 6.4 3.9 19.9 1.3 3.4 2.8 1.1 5.7 8.1 11.0 8.4 5.5 14.3 3.7 1.8 14.6 0.4 0.9 15.5 0.0 15.8 30.6 5.0 12.6 7.8 2.4 0.0 66.1 2.9 0.3 28.1 1.1 3.9 1.3 1.6 0.7 0.9 0.3 5.0 58.3 9.5 2.0 0.0 3.5 11.5 20.8 11.3 5.4 40.3 1.3 28.5 2.1 56.8 41.1 3.9 10.3 104.9 1.4 3.6 7.9 0.5 0.8 5.8 19.7 5.5 80.9 5.4 6.3 3.5 2.4 0.3 1.7 7.0 11.1 2.6 PHACTR3 "C20orf101, PPP1R123" ENSG00000087495 "Phosphatase and actin regulator 3" Q96KR7 20 59577509-59847711 "Predicted intracellular proteins" "Actin-binding, Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 104.4;choroid plexus: 36.5" "Cell type enhanced" "Detected in many" "Astrocytes: 205.7;Excitatory neurons: 100.4;Inhibitory neurons: 88.7;Oligodendrocyte precursor cells: 218.1;Oligodendrocytes: 241.1" "Group enriched" "Detected in some" 5 "glioma: 3.8;lung cancer: 1.6;pancreatic cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 85.4;HBEC3-KT: 64.6;PC-3: 113.2;THP-1: 131.3;U-937: 32.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051834, HPA054847" Enhanced Nucleoplasm NA NA "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA051834: AB_2681629, HPA054847: " "unprognostic (7.14e-2)" "unprognostic (1.22e-1)" "unprognostic (3.72e-2)" "unprognostic (1.43e-7)" "unprognostic (1.99e-1)" "unprognostic (2.87e-2)" "unprognostic (5.83e-3)" "unprognostic (8.92e-2)" "unprognostic (5.02e-2)" "unprognostic (2.30e-2)" "unprognostic (7.71e-2)" "unprognostic (7.22e-2)" "unprognostic (1.74e-2)" "unprognostic (1.66e-1)" "unprognostic (5.43e-2)" "unprognostic (2.53e-3)" "unprognostic (1.32e-1)" 0.9 1.2 90.4 0.5 92.4 0.5 0.4 82.0 93.4 0.3 36.5 0.8 0.7 1.0 0.7 1.1 8.6 1.9 4.0 82.3 75.4 2.2 0.6 5.9 0.1 78.5 82.4 6.2 0.2 0.0 1.7 0.6 76.1 0.1 0.8 3.3 0.1 0.0 0.2 1.1 1.0 0.3 74.7 5.5 0.5 0.5 93.7 1.9 0.1 1.0 0.1 0.5 0.1 104.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 85.4 0.0 6.2 1.3 0.0 0.2 0.3 64.6 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 1.4 0.1 10.5 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 17.9 0.3 0.4 113.2 0.0 0.0 0.7 25.1 1.4 2.1 6.5 0.5 0.0 0.1 0.0 0.5 131.3 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 90.4 92.4 82.0 93.4 82.3 75.4 78.5 82.4 76.1 74.7 93.7 104.4 0.3 12.8 0.5 205.7 0.3 0.6 1.3 2.1 0.0 13.8 0.2 0.0 8.9 10.0 8.4 3.7 0.0 0.0 0.0 0.0 1.9 1.1 1.0 7.1 3.7 0.3 1.2 0.0 100.4 0.0 0.0 4.2 0.0 2.1 0.0 0.5 3.3 0.0 0.2 5.0 88.7 0.9 44.7 0.3 1.1 0.9 0.0 3.7 0.0 7.5 0.0 0.8 0.0 218.1 241.1 2.9 0.1 0.0 0.9 2.9 4.3 0.1 1.3 1.9 0.0 2.9 0.9 0.3 1.0 0.1 0.4 0.0 0.1 0.9 4.5 3.2 PKNOX2 ENSG00000165495 "PBX/knotted 1 homeobox 2" Q96KN3 11 125164687-125433389 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 36.3" "Cell type enhanced" "Detected in many" "Astrocytes: 31.3;Early spermatids: 46.8;Excitatory neurons: 132.9;Inhibitory neurons: 137.4;Oligodendrocyte precursor cells: 85.5" "Cancer enhanced" "Detected in many" "melanoma: 8.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 39.1;AN3-CA: 9.6;hTEC/SVTERT24-B: 7.8;LHCN-M2: 11.6;SK-MEL-30: 7.8;WM-115: 21.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028867, CAB034342, HPA055368, HPA066962" Supported Enhanced "Nucleoplasm,Cytokinetic bridge" Yes NA "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Cytokinetic bridge" "CAB034342: AB_2164138, HPA028867: AB_2672802, HPA055368: AB_2682796, HPA066962: AB_2685757" "unprognostic (2.91e-2)" "unprognostic (1.62e-1)" "unprognostic (2.10e-2)" "unprognostic (7.26e-2)" "unprognostic (9.46e-2)" "unprognostic (3.97e-2)" "unprognostic (2.41e-1)" "unprognostic (2.12e-2)" "unprognostic (1.56e-1)" "unprognostic (2.44e-2)" "unprognostic (7.66e-2)" "unprognostic (3.70e-1)" "unprognostic (4.10e-6)" "unprognostic (1.76e-3)" "unprognostic (7.11e-2)" "unprognostic (1.71e-2)" "unprognostic (6.48e-3)" 3.6 3.3 2.6 2.0 5.8 0.0 1.2 1.4 12.7 3.2 8.1 2.8 0.9 3.3 2.7 1.4 6.1 1.8 7.3 4.8 0.6 3.0 0.5 10.0 1.4 3.0 0.3 14.9 3.9 0.9 5.6 8.4 1.3 6.3 1.4 2.8 2.5 5.1 15.0 2.4 1.7 2.6 2.6 2.3 2.3 4.8 0.8 3.1 12.1 36.3 1.1 3.1 2.7 3.1 0.0 0.0 39.1 9.6 0.7 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 4.8 0.0 0.0 0.2 0.2 0.0 0.0 0.0 1.2 0.0 0.0 2.0 0.0 7.8 0.1 0.0 0.0 0.0 0.0 0.0 11.6 0.3 0.0 0.0 3.9 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.8 6.1 0.0 0.2 0.0 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 21.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 5.8 1.4 12.7 4.8 0.6 3.0 0.3 1.3 2.6 0.8 3.1 0.6 0.0 0.0 31.3 0.0 0.9 0.0 0.0 0.0 0.9 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 1.4 46.8 0.0 1.1 0.5 0.0 0.0 132.9 0.2 0.0 3.1 0.0 0.0 0.0 12.2 1.8 0.0 0.3 8.4 137.4 0.0 0.0 0.0 0.3 9.6 5.0 0.0 8.8 22.5 0.0 2.9 0.0 85.5 3.8 0.1 0.0 17.7 0.0 1.9 0.0 0.1 0.0 0.3 6.6 8.8 2.9 1.2 0.4 0.0 0.4 0.1 0.0 6.9 0.0 0.0 PLAC9 ENSG00000189129 "Placenta associated 9" Q5JTB6 10 80131682-80145359 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 124.3" "Cell type enhanced" "Detected in many" "Fibroblasts: 926.5;Leydig cells: 873.5;Peritubular cells: 659.7;Sertoli cells: 295.9;Smooth muscle cells: 446.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.0" "Cell line enhanced" "Detected in many" "ASC diff: 98.5;ASC TERT1: 85.3;BEWO: 32.1;HSkMC: 28.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 37.9" HPA043469 Uncertain "Secreted - unknown location" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA043469: AB_10795770" "unprognostic (1.72e-1)" "unprognostic (4.22e-2)" "unprognostic (5.01e-3)" "unprognostic (1.78e-2)" "unprognostic (2.76e-1)" "unprognostic (3.93e-1)" "unprognostic (5.57e-3)" "unprognostic (5.88e-3)" "unprognostic (8.45e-2)" "prognostic unfavorable (6.60e-4)" "unprognostic (1.30e-2)" "unprognostic (1.09e-1)" "unprognostic (4.23e-3)" "unprognostic (4.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.14e-1)" "unprognostic (2.82e-3)" 112.3 18.4 10.2 6.6 9.2 1.2 85.7 10.3 15.5 77.3 53.3 22.1 4.0 26.9 5.0 21.4 30.4 9.0 124.3 14.3 5.9 17.9 6.4 56.1 2.7 5.9 5.8 11.5 5.7 4.1 4.9 12.5 6.4 35.9 4.6 0.6 20.1 7.6 16.9 47.8 19.7 6.5 6.5 5.0 21.4 14.9 6.9 2.2 44.6 19.2 1.9 54.0 75.7 8.5 0.2 0.0 0.8 0.0 98.5 85.3 32.1 10.3 8.7 0.9 1.2 0.0 0.7 0.0 0.2 6.0 0.1 0.8 0.1 0.0 0.0 0.8 0.3 0.0 0.5 0.0 16.4 0.0 2.3 28.7 0.0 2.1 1.2 10.6 3.4 0.4 0.0 0.4 0.0 0.3 0.1 0.6 1.9 0.4 1.5 0.0 0.1 1.5 0.0 0.6 0.0 1.8 0.0 1.2 0.7 0.2 0.1 0.2 3.6 6.6 3.6 21.0 0.2 0.7 0.9 0.1 1.9 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 10.2 9.2 10.3 15.5 14.3 5.9 5.9 5.8 6.4 6.5 6.9 8.5 246.2 3.2 1.8 0.0 1.6 126.4 0.7 1.1 8.0 0.4 7.4 14.0 24.4 0.0 0.3 0.0 0.0 7.0 3.6 0.1 0.0 0.3 4.6 3.1 75.7 102.5 1.8 0.0 0.5 0.2 17.7 926.5 5.6 4.4 1.3 0.1 115.6 0.3 14.1 0.0 0.5 0.0 0.0 0.0 191.3 26.7 873.5 7.9 136.9 7.5 0.0 50.2 0.0 0.0 0.2 0.7 0.0 659.7 2.1 1.0 0.0 0.2 0.9 1.7 295.9 89.7 446.6 2.6 2.9 4.6 126.3 11.5 14.1 1.1 0.0 1.8 PLCB4 ENSG00000101333 "Phospholipase C beta 4" Q15147 20 9068763-9481242 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 55.6;salivary gland: 57.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 105.9;Horizontal cells: 164.9;Inhibitory neurons: 113.8;Microglial cells: 183.6;Oligodendrocyte precursor cells: 168.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.5" "Region enhanced" "Detected in all" "cerebellum: 55.6" "Immune cell enriched" "Detected in single" 18 "plasmacytoid DC: 3.0" "Lineage enriched" "Detected in single" 18 "dendritic cells: 3.0" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 91.4;hTERT-HME1: 45.9;LHCN-M2: 77.6;OE19: 48.2;RPTEC TERT1: 96.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007951 Approved Approved Nucleoplasm,Microtubules NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 21: Non-specific - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Microtubules Nucleoplasm "HPA007951: AB_2667944" "unprognostic (3.88e-2)" "unprognostic (3.62e-1)" "unprognostic (1.19e-2)" "prognostic favorable (2.11e-4)" "unprognostic (1.44e-2)" "unprognostic (9.72e-3)" "unprognostic (3.32e-3)" "unprognostic (2.57e-2)" "unprognostic (7.75e-2)" "unprognostic (4.23e-2)" "unprognostic (5.21e-3)" "unprognostic (1.35e-1)" "unprognostic (4.64e-3)" "unprognostic (7.12e-2)" "unprognostic (1.37e-1)" "unprognostic (2.22e-1)" "unprognostic (4.45e-2)" 6.3 7.2 8.6 3.4 3.7 0.5 7.0 55.6 6.3 4.6 31.0 20.5 2.6 8.2 24.4 9.0 15.0 5.9 17.9 2.5 10.8 3.0 0.3 5.4 1.7 13.4 17.8 2.1 2.1 0.7 8.2 6.5 12.0 9.7 17.9 15.1 57.4 6.1 2.7 4.6 4.2 9.1 5.3 1.3 14.4 2.4 23.3 4.5 32.7 6.8 2.3 8.2 5.3 6.5 0.0 15.1 7.9 0.0 0.0 0.4 0.1 35.8 9.5 10.9 6.1 3.4 2.6 0.0 0.6 91.4 39.0 0.1 2.3 7.6 14.7 0.0 5.3 3.8 5.7 0.0 1.6 0.0 0.0 2.3 3.0 12.7 45.9 18.7 0.1 0.0 4.3 0.4 77.6 5.0 0.0 0.0 8.8 48.2 10.4 0.0 0.0 0.7 96.9 5.8 25.5 18.4 0.0 23.8 15.1 10.5 19.2 0.2 0.5 11.2 0.9 1.2 14.2 0.0 0.0 0.0 1.7 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.0 0.0 0.0 8.6 3.7 55.6 6.3 2.5 10.8 13.4 17.8 12.0 5.3 23.3 6.5 37.8 6.4 0.5 60.1 0.3 2.4 3.8 1.5 2.2 82.9 5.7 5.3 72.6 0.0 8.9 5.5 0.0 0.0 4.5 17.9 0.0 0.7 1.4 46.2 4.6 40.4 42.0 0.0 105.9 0.2 0.0 9.0 18.8 53.5 0.0 36.6 1.8 0.0 0.1 164.9 113.8 36.4 14.2 0.0 2.1 1.2 1.5 0.8 7.2 183.6 0.6 2.9 0.0 168.9 2.9 7.1 9.7 20.7 0.2 8.5 2.1 1.2 39.5 6.6 13.1 10.5 36.0 1.5 2.0 0.5 1.0 0.1 1.4 4.8 40.4 2.5 PLCL1 "PLC-L, PLCE, PLCL, PPP1R127, PRIP" ENSG00000115896 "Phospholipase C like 1 (inactive)" Q15111 2 197804593-198572581 "Metabolic proteins, Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.3;tongue: 40.8" "Cell type enriched" "Detected in many" 10 "Oligodendrocytes: 2062.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.4" "Lineage enriched" "Detected in single" 6 "T-cells: 1.4" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 8.7;K-562: 15.6;Karpas-707: 10.7;MOLT-4: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031849 Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA031849: AB_10602192" "unprognostic (7.77e-3)" "unprognostic (2.57e-1)" "unprognostic (2.09e-1)" "unprognostic (5.18e-3)" "unprognostic (4.40e-2)" "unprognostic (7.14e-2)" "unprognostic (2.05e-1)" "unprognostic (4.42e-3)" "unprognostic (1.07e-1)" "unprognostic (1.32e-1)" "unprognostic (3.02e-2)" "unprognostic (7.42e-2)" "prognostic favorable (3.91e-7)" "unprognostic (1.07e-4)" "unprognostic (6.74e-2)" "unprognostic (1.68e-1)" "unprognostic (3.20e-2)" 4.0 4.1 15.6 2.7 40.5 1.6 2.4 32.5 21.4 4.5 9.5 4.0 0.6 14.8 3.1 3.6 3.3 3.0 32.4 13.8 30.8 31.5 0.5 3.2 3.4 42.6 37.4 7.0 1.6 14.8 2.1 7.9 39.2 10.5 1.3 4.0 2.3 7.1 30.8 0.9 1.8 6.0 22.6 1.9 2.2 1.7 27.7 17.2 3.3 40.8 2.6 4.1 1.9 65.3 0.0 0.0 0.1 0.0 1.6 0.4 0.0 0.4 0.2 0.1 0.1 0.0 0.1 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 1.5 0.0 0.2 0.0 1.8 4.2 0.0 0.0 0.0 0.0 8.7 2.9 15.6 10.7 0.1 0.4 11.4 0.0 0.1 0.0 0.0 0.0 0.0 4.7 0.2 0.0 1.6 0.9 1.8 0.0 2.5 0.8 0.2 0.0 0.7 0.2 0.0 0.0 0.1 4.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.6 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.0 1.4 0.0 15.6 40.5 32.5 21.4 13.8 30.8 42.6 37.4 39.2 22.6 27.7 65.3 7.0 19.2 4.4 44.4 0.9 1.3 0.8 0.0 0.6 14.8 2.0 1.8 159.0 1.5 1.9 14.7 0.0 0.1 0.8 1.8 58.7 0.9 15.5 2.0 102.7 5.4 1.8 0.0 201.0 0.4 0.0 6.0 1.1 1.9 6.3 3.8 0.4 0.0 3.1 15.2 160.9 0.0 2.0 4.1 2.0 3.8 1.8 4.6 0.0 49.6 2.9 2.7 0.0 181.5 2062.6 0.2 0.0 7.9 3.8 0.6 0.6 52.4 2.2 1.2 32.9 5.4 31.8 1.0 1.8 0.2 1.3 0.1 8.2 1.6 0.1 0.3 PLPP4 "DPPL2, PPAPDC1, PPAPDC1A" ENSG00000203805 "Phospholipid phosphatase 4" Q5VZY2 10 120457227-120592065 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "brain: 12.2" "Cell type enhanced" "Detected in some" "Cholangiocytes: 11.5;Distal tubular cells: 7.9;Early spermatids: 10.9;Erythroid cells: 9.7;Late spermatids: 10.7;Leydig cells: 19.3;Peritubular cells: 7.9;Proximal tubular cells: 9.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "hTERT-RPE1: 14.2;U-251 MG: 10.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045188 Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA045188: AB_2679246" "unprognostic (8.19e-2)" "unprognostic (2.94e-2)" "unprognostic (8.86e-2)" "unprognostic (1.90e-3)" "unprognostic (3.45e-1)" "unprognostic (2.92e-2)" "unprognostic (2.69e-1)" "unprognostic (2.26e-3)" "unprognostic (1.55e-1)" "unprognostic (8.62e-3)" "unprognostic (2.70e-3)" "unprognostic (1.89e-1)" "unprognostic (2.40e-3)" "unprognostic (3.49e-2)" "unprognostic (3.75e-2)" "unprognostic (1.11e-1)" "unprognostic (1.21e-3)" 0.0 0.0 2.9 0.1 3.5 0.4 0.1 6.4 2.8 0.2 0.5 0.3 0.0 0.1 0.0 0.0 0.0 0.6 0.0 5.3 8.9 0.8 0.1 0.0 0.0 11.0 5.3 0.0 0.0 0.0 0.0 0.0 12.2 0.2 0.0 0.1 0.0 0.2 0.1 0.2 0.1 0.1 4.3 0.0 0.0 0.9 3.7 0.1 0.0 0.0 0.0 0.0 0.1 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.3 0.2 0.0 0.3 0.1 0.0 1.7 1.4 0.0 0.1 0.1 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 14.2 1.3 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.1 0.0 0.1 0.9 0.2 0.0 2.8 1.7 1.2 0.1 10.4 0.0 0.0 0.0 2.3 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 2.9 3.5 6.4 2.8 5.3 8.9 11.0 5.3 12.2 4.3 3.7 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 11.5 0.0 3.7 0.0 0.0 0.0 0.0 7.9 0.3 10.9 0.1 2.5 0.0 0.0 9.7 0.0 0.2 0.1 0.3 0.0 0.1 0.0 0.2 1.8 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 10.7 19.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 7.9 0.0 0.5 0.0 9.0 0.0 0.0 0.0 0.0 4.9 1.5 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 PNMA8B "KIAA1183, PNMAL2" ENSG00000204851 "PNMA family member 8B" Q9ULN7 19 46486906-46495879 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 14.7;brain: 41.6" "Group enriched" "Detected in some" 4 "Adipocytes: 8.3;Granulosa cells: 5.3;Theca cells: 12.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.4;AN3-CA: 1.8;SH-SY5Y: 1.4" "Low region specificity" "Detected in all" HPA054810 Enhanced NA NA "Cluster 65: Brain - Ion transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 52: Non-specific - Transcription" "HPA054810: AB_2682609" "unprognostic (1.31e-2)" "unprognostic (2.81e-2)" "unprognostic (3.27e-2)" "unprognostic (1.34e-1)" "unprognostic (5.97e-2)" "unprognostic (3.38e-3)" "unprognostic (2.90e-1)" "unprognostic (1.35e-1)" "unprognostic (4.15e-1)" "unprognostic (4.19e-3)" "unprognostic (4.26e-4)" "unprognostic (7.30e-2)" "unprognostic (5.57e-3)" "unprognostic (1.84e-2)" "unprognostic (1.07e-1)" "unprognostic (3.38e-1)" "unprognostic (1.32e-2)" 2.7 14.7 32.8 0.3 31.1 0.0 2.4 0.0 41.6 1.9 0.0 1.5 0.3 1.7 0.5 0.5 1.6 1.0 1.9 20.1 25.3 0.7 0.4 0.7 0.4 22.5 15.0 3.9 0.9 0.2 7.3 0.3 27.3 1.6 0.1 2.1 1.5 1.0 0.5 2.3 0.9 0.6 2.1 1.9 0.9 0.8 18.5 3.5 0.8 0.4 0.1 1.1 1.6 19.0 0.0 0.0 1.4 1.8 0.4 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 31.1 0.0 41.6 20.1 25.3 22.5 15.0 27.3 2.1 18.5 19.0 8.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.9 0.3 0.0 0.5 0.9 0.8 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.1 0.0 5.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 12.4 0.0 0.0 PODN "MGC24995, PCAN, PODOCAN, SLRR5A" ENSG00000174348 Podocan Q7Z5L7 1 53062052-53085501 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 13 "Fibroblasts: 123.5;Leydig cells: 268.7;Peritubular cells: 261.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "gdT-cell: 5.1;memory CD8 T-cell: 1.4;naive CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 52 "T-cells: 5.1" "Cell line enhanced" "Detected in some" "ASC diff: 23.0;BJ: 39.2;fHDF/TERT166: 23.9;HHSteC: 94.1;U-2197: 46.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 910000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (8.69e-2)" "unprognostic (4.73e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (2.31e-1)" "unprognostic (1.88e-1)" "unprognostic (3.65e-1)" "unprognostic (1.90e-3)" "unprognostic (1.71e-1)" "unprognostic (3.53e-2)" "prognostic unfavorable (2.02e-5)" "unprognostic (5.91e-3)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (5.02e-2)" 191.0 14.3 9.1 13.3 8.2 0.2 116.3 6.4 8.7 106.1 7.1 76.1 11.6 105.1 19.7 36.1 127.5 103.8 87.1 6.8 8.1 5.2 12.5 66.3 3.8 7.3 10.3 178.0 20.8 2.9 19.5 18.1 8.2 69.8 8.2 0.6 48.8 34.4 20.2 45.4 26.1 44.7 6.7 3.3 75.5 26.9 10.3 10.8 71.5 30.5 2.7 101.3 87.9 6.7 0.0 0.0 0.0 0.0 23.0 3.1 0.1 39.2 5.3 0.4 0.3 0.0 0.0 0.0 0.6 23.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.1 0.0 0.0 14.9 0.0 0.9 0.0 1.0 1.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.1 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.0 0.0 46.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.3 1.4 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.8 9.1 8.2 6.4 8.7 6.8 8.1 7.3 10.3 8.2 6.7 10.3 6.7 8.5 0.0 3.3 0.0 0.0 6.4 0.4 0.0 0.6 0.5 0.8 0.9 1.7 1.5 0.6 0.0 0.0 0.4 1.3 0.0 0.0 0.0 1.6 0.3 11.2 3.8 0.0 0.0 0.0 0.0 0.4 123.5 2.6 0.3 0.0 0.7 4.2 0.1 0.6 0.0 1.9 0.0 0.0 0.3 8.8 9.2 268.7 1.3 5.4 6.5 0.0 0.3 3.1 5.5 0.2 0.0 0.0 261.1 1.6 0.5 0.1 0.0 0.0 0.5 0.0 4.4 16.0 0.7 0.6 0.7 6.0 0.5 1.6 0.0 0.0 0.2 PPP1R12B "MGC131980, MGC87886, MYPT2, PP1bp55" ENSG00000077157 "Protein phosphatase 1 regulatory subunit 12B" O60237 1 202348699-202592706 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 356.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 836.8;Excitatory neurons: 225.7;Granulosa cells: 438.3;Oligodendrocytes: 647.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 16.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 16.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024171, HPA024640" Enhanced Approved "Plasma membrane,Actin filaments" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Actin filaments" "HPA024171: AB_1854266, HPA024640: AB_1854265" "unprognostic (5.24e-2)" "unprognostic (8.59e-2)" "unprognostic (1.38e-1)" "unprognostic (2.75e-2)" "unprognostic (3.04e-1)" "unprognostic (5.45e-3)" "unprognostic (3.12e-2)" "unprognostic (9.13e-3)" "unprognostic (4.05e-2)" "unprognostic (3.74e-2)" "unprognostic (2.79e-2)" "unprognostic (1.80e-1)" "unprognostic (3.60e-3)" "unprognostic (6.98e-3)" "unprognostic (1.27e-1)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" 40.0 11.1 5.1 36.0 12.6 8.3 17.8 8.9 9.9 51.8 15.5 151.0 24.1 222.0 30.5 150.1 52.6 72.5 356.9 5.5 6.5 14.3 8.4 24.8 18.6 17.2 15.3 38.3 7.2 6.2 5.0 34.4 18.0 142.8 64.8 7.6 20.0 198.6 84.1 11.0 30.9 246.4 16.2 30.8 41.5 7.1 9.2 7.7 10.9 80.5 15.1 86.7 23.0 27.3 2.2 4.4 3.3 3.2 4.6 3.3 5.4 1.7 1.7 1.8 1.7 1.9 3.9 2.5 0.8 3.2 4.3 7.0 5.0 2.7 1.9 3.3 3.1 2.5 7.1 1.2 1.1 5.4 2.8 2.6 3.0 2.5 2.6 9.1 1.5 2.8 3.9 2.9 3.1 1.7 4.1 3.4 2.3 2.4 0.9 2.6 8.5 3.7 1.4 8.1 4.0 3.1 3.3 3.9 1.9 4.4 3.4 2.4 1.9 2.5 1.5 1.9 1.5 4.2 4.3 2.7 2.4 4.4 10.2 2.4 1.7 1.5 1.6 1.0 1.4 2.0 1.1 1.0 1.5 2.1 1.3 1.0 16.2 0.7 1.5 1.7 1.7 0.5 5.1 12.6 8.9 9.9 5.5 6.5 17.2 15.3 18.0 16.2 9.2 27.3 12.5 12.8 19.8 181.5 6.0 17.3 49.0 35.6 8.6 59.3 11.1 20.6 836.8 11.5 23.0 12.9 75.0 18.1 8.6 52.9 11.7 10.1 39.2 19.3 16.1 15.2 24.0 5.2 225.7 12.9 8.4 51.4 17.3 7.6 18.9 438.3 16.4 9.6 9.4 26.9 205.0 17.2 63.1 23.5 10.9 13.1 12.2 8.2 8.8 102.1 7.8 10.2 5.2 102.5 647.4 6.3 21.1 51.1 9.6 24.3 12.8 7.1 27.4 30.4 32.9 38.6 162.7 19.3 13.9 7.1 10.9 25.4 10.7 14.2 33.9 28.4 PRELP "prolargin, SLRR2A" ENSG00000188783 "Proline and arginine rich end leucine rich repeat protein" P51888 1 203475806-203491352 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Fibroblasts: 206.6;Leydig cells: 100.6;Melanocytes: 192.1;Muller glia cells: 152.4;Peritubular cells: 199.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.1" "Group enriched" "Detected in some" 5 "ASC diff: 18.0;BJ: 7.7;fHDF/TERT166: 11.7;SuSa: 5.2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 82.4" HPA059225 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 450000 "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA059225: " "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "prognostic unfavorable (9.70e-5)" "unprognostic (2.83e-2)" "unprognostic (6.56e-2)" "unprognostic (2.75e-2)" "unprognostic (1.61e-1)" "unprognostic (2.84e-2)" "unprognostic (3.98e-2)" "unprognostic (2.04e-1)" "unprognostic (2.80e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (5.62e-6)" "unprognostic (2.81e-2)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.02e-4)" 114.8 23.4 12.6 4.2 14.2 0.5 77.5 7.7 20.2 126.7 20.0 136.4 6.6 147.7 7.6 41.3 108.6 40.4 212.0 11.6 10.0 25.3 15.6 124.7 8.0 10.2 8.2 128.2 13.1 2.5 22.6 12.0 9.4 73.6 8.9 21.5 32.7 77.1 35.6 56.4 61.0 51.4 8.3 44.2 41.3 7.2 10.3 3.2 60.4 36.9 15.9 147.8 92.9 9.4 0.2 0.2 0.5 0.1 18.0 0.5 0.4 7.7 1.0 0.2 0.2 0.0 0.1 1.2 0.6 11.7 0.1 0.6 0.2 0.3 0.3 0.0 0.1 0.2 0.5 0.2 0.0 0.3 0.1 0.0 0.0 0.1 0.2 2.1 0.0 0.4 0.2 0.4 1.3 0.1 0.1 0.5 0.4 0.3 0.1 0.4 0.2 0.4 0.0 0.3 1.0 0.2 0.2 0.2 0.8 5.2 0.2 0.1 0.6 0.5 0.2 0.3 0.1 0.2 0.3 1.2 0.1 0.2 0.5 1.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.1 0.1 0.1 0.0 12.6 14.2 7.7 20.2 11.6 10.0 10.2 8.2 9.4 8.3 10.3 9.4 8.8 0.0 5.8 5.2 0.9 18.2 1.0 0.0 2.2 3.6 4.2 5.1 7.4 1.5 0.6 0.0 2.1 0.1 0.3 0.1 0.0 0.0 1.1 0.6 1.7 15.6 0.0 2.7 1.6 0.0 0.1 206.6 4.6 1.6 5.1 0.2 22.9 0.3 0.3 1.7 0.2 0.0 0.0 0.3 19.2 5.3 100.6 0.9 192.1 22.5 0.0 152.4 0.0 7.5 0.5 0.0 0.0 199.7 0.4 0.6 0.0 0.1 1.5 8.9 26.3 9.6 38.3 3.1 2.4 1.6 9.9 0.3 1.6 0.1 0.0 1.3 PRSS35 "C6orf158, dJ223E3.1, MGC46520" ENSG00000146250 "Serine protease 35" Q8N3Z0 6 83512534-83525704 "Enzymes, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 50.5" "Cell type enriched" "Detected in some" 36 "Muller glia cells: 410.9" "Group enriched" "Detected in some" 4 "glioma: 2.8;testis cancer: 4.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "MAIT T-cell: 19.5" "Lineage enriched" "Detected in single" 195 "T-cells: 19.5" "Cell line enhanced" "Detected in some" "BJ hTERT+: 10.4;CACO-2: 86.3;HAP1: 12.8;RPTEC TERT1: 24.6;SuSa: 17.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 2.9;cerebellum: 3.6;cerebral cortex: 5.8;hippocampal formation: 5.3;olfactory bulb: 2.7" "HPA038787, HPA038788" Uncertain "Secreted in female reproductive system" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 5: Muller glia cells - Visual perception" "HPA038787: AB_10675951, HPA038788: AB_2676208" "unprognostic (6.17e-2)" "unprognostic (8.75e-2)" "unprognostic (1.19e-2)" "unprognostic (2.63e-2)" "unprognostic (1.16e-1)" "unprognostic (4.03e-2)" "unprognostic (3.70e-4)" "unprognostic (6.08e-2)" "unprognostic (1.18e-3)" "unprognostic (2.33e-2)" "unprognostic (7.01e-2)" "unprognostic (9.07e-2)" "unprognostic (3.88e-6)" "unprognostic (7.15e-3)" "unprognostic (5.81e-2)" "unprognostic (2.82e-2)" "unprognostic (3.54e-4)" 1.3 2.4 2.9 0.1 3.8 0.0 0.3 1.7 6.8 2.9 1.5 0.1 0.3 1.3 1.1 0.3 1.4 4.2 4.4 3.2 2.1 3.1 0.4 1.3 0.7 1.8 1.9 10.2 0.3 0.3 1.1 3.6 1.8 1.1 0.3 50.5 0.3 0.4 0.1 0.2 0.1 1.5 1.8 0.7 0.3 3.1 2.6 0.1 0.4 0.1 0.1 1.3 0.5 2.2 0.0 0.5 1.9 0.0 0.1 0.0 0.0 0.3 10.4 1.0 2.0 86.3 0.0 0.0 0.1 0.4 0.0 0.0 12.8 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 3.1 0.0 1.2 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.1 1.6 0.4 8.2 0.0 0.0 0.0 24.6 0.0 0.0 1.0 0.0 0.0 0.0 17.9 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 19.5 0.0 0.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 3.8 1.7 6.8 3.2 2.1 1.8 1.9 1.8 1.8 2.6 2.2 0.3 3.2 0.5 8.1 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.1 1.5 0.0 0.0 1.8 0.0 0.3 0.0 0.1 9.8 0.1 0.1 0.0 0.3 0.8 1.8 0.0 0.2 0.0 0.0 4.4 0.0 0.0 0.0 0.9 0.0 0.3 0.4 6.7 0.2 0.0 0.0 0.0 0.0 0.2 1.2 0.1 0.0 1.0 0.0 410.9 0.0 1.0 0.1 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 11.4 6.6 0.1 3.7 0.1 0.5 0.0 0.0 0.1 0.7 5.1 0.0 0.0 PTGDS "L-PGDS, PGDS" ENSG00000107317 "Prostaglandin D2 synthase" P41222 9 136975092-136981742 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Mast cell degranulation, Prostaglandin biosynthesis, Prostaglandin metabolism, Transport" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 4898.3;testis: 3242.2" "Group enriched" "Detected in many" 11 "Leydig cells: 38051.3;Peritubular cells: 65156.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 27 "plasmacytoid DC: 1386.8" "Lineage enriched" "Detected in many" 27 "dendritic cells: 1386.8" "Group enriched" "Detected in some" 6 "HHSteC: 518.7;HSkMC: 252.0" "HPA004938, CAB009916, HPA067456" Uncertain "Secreted to blood" NA NA 2500000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "CAB009916: AB_2174617, HPA004938: AB_1855745, HPA067456: " "unprognostic (2.79e-2)" "unprognostic (3.96e-3)" "unprognostic (9.70e-2)" "unprognostic (5.71e-3)" "unprognostic (6.50e-2)" "unprognostic (1.43e-3)" "unprognostic (2.85e-1)" "unprognostic (2.01e-2)" "unprognostic (6.50e-2)" "unprognostic (1.31e-2)" "unprognostic (1.95e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (1.19e-7)" "unprognostic (8.49e-3)" "unprognostic (1.18e-1)" "unprognostic (2.44e-1)" "unprognostic (3.21e-2)" 391.1 297.1 1849.2 247.1 2423.8 9.9 121.1 2440.1 2559.6 1675.5 1508.4 84.8 31.5 320.4 735.9 172.5 492.1 396.7 4898.3 1760.9 2034.8 466.5 80.2 607.8 824.1 2339.4 2228.2 66.8 113.2 9.1 398.4 227.8 2318.0 727.0 17.7 146.1 97.8 813.1 108.3 164.9 205.9 99.7 1999.6 317.5 93.0 3242.2 2264.9 127.4 55.1 60.0 306.0 230.3 1181.0 2580.3 0.1 0.0 0.1 0.0 5.4 16.7 8.8 0.3 0.0 0.0 0.0 0.0 0.2 0.6 4.0 24.0 0.0 0.8 0.6 0.2 0.0 0.0 0.0 0.0 1.4 0.3 518.7 0.3 1.3 252.0 0.1 0.0 0.0 1.8 0.0 0.0 0.6 1.0 0.2 0.0 0.0 6.6 0.9 8.2 0.0 0.1 0.2 1.6 0.0 0.0 1.6 2.0 0.0 0.6 0.0 0.1 0.6 68.3 0.7 0.2 0.2 2.1 0.1 0.3 0.0 0.1 3.9 0.0 0.9 0.0 0.3 0.4 50.5 1.0 3.4 0.3 4.3 6.3 1.8 0.2 0.9 9.9 2.3 3.8 0.2 1386.8 1.4 11.2 1849.2 2423.8 2440.1 2559.6 1760.9 2034.8 2339.4 2228.2 2318.0 1999.6 2264.9 2580.3 29.3 0.0 0.6 665.0 1.5 70.4 3.2 0.1 5.7 46.8 6.6 14.7 333.6 8.6 0.1 138.0 52.1 14.4 1863.6 0.2 68.4 0.3 215.9 29.7 1156.5 167.8 0.0 13.5 4.0 0.0 55.0 1584.0 1.1 20.1 1.3 0.3 46.1 1.6 57.3 21.9 12.8 0.0 0.0 3.4 161.8 1230.9 38051.3 57.0 209.9 176.1 4.6 4625.8 583.9 63.3 850.4 1.7 0.0 65156.8 6.0 20.7 0.0 1.1 0.0 130.3 164.3 787.4 124.8 130.7 111.1 12.0 80.1 35.4 61.3 0.1 0.0 14.5 PTPN13 "PTP-BAS, PTP-BL, PTP1E, PTPL1" ENSG00000163629 "Protein tyrosine phosphatase non-receptor type 13" Q12923 4 86594315-86815171 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 124.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 223.1;Astrocytes: 165.2;Oligodendrocytes: 200.2;Rod photoreceptor cells: 179.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 117.6;RT4: 57.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002213, HPA063119" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "CAB002213: AB_564089, HPA063119: " "unprognostic (5.36e-2)" "unprognostic (4.46e-1)" "unprognostic (1.11e-1)" "unprognostic (2.54e-3)" "unprognostic (4.02e-1)" "unprognostic (9.03e-3)" "unprognostic (4.43e-2)" "unprognostic (4.38e-2)" "unprognostic (2.46e-1)" "unprognostic (7.05e-2)" "unprognostic (3.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.28e-3)" "unprognostic (3.95e-3)" "unprognostic (2.26e-1)" "unprognostic (2.66e-1)" "unprognostic (2.85e-2)" 14.0 6.7 9.9 3.0 16.6 0.3 11.7 8.1 10.8 18.8 22.4 5.2 0.8 13.1 25.5 22.2 13.0 7.7 6.1 14.2 10.6 26.6 1.4 22.9 5.2 16.7 13.1 28.7 4.9 17.5 16.8 3.3 10.5 11.0 2.4 124.3 6.6 10.6 1.0 55.9 2.6 7.9 8.2 4.0 4.1 15.8 13.8 7.6 20.8 5.0 11.5 20.7 22.7 20.4 13.8 6.8 117.6 11.5 48.2 41.9 0.0 25.0 51.0 9.4 11.7 0.1 6.8 0.0 5.3 28.0 3.3 44.4 20.6 37.9 18.0 0.3 15.1 11.4 14.6 0.0 5.9 20.5 0.1 27.2 11.8 6.8 22.4 19.7 0.0 0.0 0.0 19.2 0.0 6.2 1.8 7.4 26.5 0.0 5.1 4.1 0.0 0.0 35.6 57.2 6.8 9.8 7.4 16.4 13.3 18.8 9.6 0.7 0.0 9.1 6.9 0.2 3.3 19.8 0.0 0.0 9.5 0.0 4.0 0.0 0.1 0.0 0.1 1.3 0.9 0.0 0.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 9.9 16.6 8.1 10.8 14.2 10.6 16.7 13.1 10.5 8.2 13.8 20.4 5.3 48.1 223.1 165.2 0.6 109.4 25.6 26.3 79.1 11.6 11.2 8.9 1.8 11.5 52.0 47.8 91.8 0.2 0.3 0.1 3.9 5.0 23.2 16.9 49.4 3.7 4.8 0.8 67.0 3.7 0.1 28.8 4.1 7.7 5.1 7.5 3.6 0.1 0.3 1.7 39.3 1.1 8.2 1.4 10.6 20.8 45.7 4.5 19.6 51.5 0.5 20.3 0.0 75.4 200.2 6.2 2.7 32.7 3.0 16.0 0.1 10.9 27.3 179.0 13.1 10.1 20.8 25.4 20.5 97.8 99.4 0.3 6.6 14.0 0.7 52.5 PYGO1 ENSG00000171016 "Pygopus family PHD finger 1" Q9Y3Y4 15 55538884-55588947 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 23.5;Endometrial stromal cells: 18.2;Inhibitory neurons: 30.4;Oligodendrocyte precursor cells: 59.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-698: 33.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042248 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm Cytosol "HPA042248: AB_10794272" "unprognostic (5.55e-2)" "unprognostic (9.82e-2)" "unprognostic (2.61e-2)" "unprognostic (4.54e-2)" "unprognostic (7.20e-2)" "unprognostic (1.61e-1)" "unprognostic (1.31e-1)" "unprognostic (8.23e-2)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" "unprognostic (2.68e-1)" "unprognostic (2.29e-1)" "unprognostic (6.72e-6)" "unprognostic (3.36e-4)" "unprognostic (4.84e-2)" "unprognostic (2.30e-2)" "unprognostic (1.80e-2)" 1.8 2.3 2.6 0.9 3.0 0.2 1.7 7.3 2.3 3.7 2.9 3.2 0.4 5.6 2.0 1.8 2.5 2.3 1.3 2.6 4.6 0.9 0.1 1.9 0.5 3.3 4.5 6.1 1.4 13.2 3.0 2.0 3.1 4.5 1.0 4.5 0.9 4.8 11.7 0.7 0.9 4.7 3.3 0.3 1.4 3.2 4.9 0.4 6.8 9.1 0.4 2.2 1.7 2.4 3.7 6.3 12.2 6.2 4.4 10.0 4.6 7.8 8.9 6.2 7.1 4.5 0.0 0.0 2.4 5.3 8.9 0.0 12.4 0.1 8.3 0.0 3.9 1.8 1.8 0.4 5.9 6.6 0.0 5.5 6.2 5.5 0.9 6.9 3.2 1.0 0.1 0.0 10.3 0.1 0.3 0.0 3.3 0.9 3.4 0.0 14.8 0.0 2.1 2.7 6.5 7.3 7.6 0.0 5.6 1.7 2.3 2.1 0.0 15.8 6.9 0.3 9.5 0.2 0.2 33.6 4.9 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.0 7.3 2.3 2.6 4.6 3.3 4.5 3.1 3.3 4.9 2.4 0.6 9.6 6.3 23.5 0.0 1.7 5.9 0.1 4.6 5.6 2.4 3.6 6.1 0.0 1.9 9.2 0.0 1.5 0.1 0.0 0.0 0.5 2.9 1.6 18.2 1.1 0.0 0.0 1.8 0.0 0.2 9.3 0.0 1.9 0.0 7.1 1.1 0.0 0.5 0.0 30.4 0.0 0.0 0.6 1.4 2.6 9.9 0.3 7.2 4.7 0.0 7.0 0.0 59.8 1.9 0.5 0.0 12.0 0.0 5.7 0.0 0.2 1.8 4.5 0.0 12.7 6.1 11.6 2.8 1.4 0.9 0.3 0.6 2.0 0.0 0.7 RBMS3 ENSG00000144642 "RNA binding motif single stranded interacting protein 3" Q6XE24 3 28574791-30010391 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 331.1;Inhibitory neurons: 655.9;Microglial cells: 1013.7;Oligodendrocyte precursor cells: 229.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 5.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "plasmacytoid DC: 3.9" "Lineage enriched" "Detected in single" 9 "dendritic cells: 3.9" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 20.7;WM-115: 24.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034719 Uncertain Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA034719: AB_10670172" "unprognostic (8.39e-2)" "unprognostic (2.54e-2)" "unprognostic (1.02e-1)" "unprognostic (7.08e-2)" "unprognostic (2.29e-1)" "unprognostic (1.33e-1)" "unprognostic (3.13e-2)" "unprognostic (4.95e-2)" "unprognostic (1.08e-1)" "unprognostic (3.90e-2)" "unprognostic (1.90e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (1.85e-4)" "unprognostic (2.25e-3)" "unprognostic (3.81e-2)" "unprognostic (8.48e-2)" "unprognostic (3.24e-4)" 15.8 8.6 6.5 2.1 7.2 0.1 12.2 9.5 5.8 9.9 12.0 8.1 1.4 6.2 6.7 3.1 9.8 6.7 14.3 2.1 21.4 5.1 3.7 12.6 2.7 12.6 15.7 11.6 2.0 4.9 3.2 10.4 9.0 6.4 2.6 0.4 4.7 8.7 6.4 3.8 4.0 4.5 6.3 6.6 4.3 2.2 11.1 5.5 15.3 10.8 1.7 8.1 7.3 2.6 2.2 0.2 10.2 0.1 19.6 12.5 0.0 5.7 3.6 5.9 6.8 0.0 0.4 0.0 6.1 20.7 1.8 0.2 0.5 3.8 10.9 0.0 1.1 5.9 8.7 0.0 19.9 0.1 0.0 11.8 2.6 10.5 12.3 8.4 7.9 0.0 0.0 0.0 7.4 0.0 0.1 0.0 0.3 0.0 0.4 0.4 7.5 0.0 2.2 0.0 0.0 19.4 13.7 0.0 0.7 4.6 0.0 0.0 17.1 11.1 11.6 13.5 11.7 0.0 0.0 0.8 1.5 0.0 24.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 3.9 0.3 0.0 6.5 7.2 9.5 5.8 2.1 21.4 12.6 15.7 9.0 6.3 11.1 2.6 100.9 118.6 18.8 331.1 0.6 8.3 25.5 23.0 2.2 0.4 2.7 19.8 16.2 31.5 21.3 9.2 0.0 16.4 5.9 0.0 0.0 5.3 35.1 2.8 7.0 54.4 0.0 0.0 20.7 1.2 3.0 96.8 2.0 4.6 5.1 19.8 129.9 1.9 2.8 0.0 655.9 0.0 6.1 30.3 14.1 18.8 159.7 2.7 7.2 1013.7 0.6 0.0 0.0 229.2 8.9 0.4 0.0 110.6 0.1 24.3 0.0 2.9 10.5 0.0 111.7 154.6 73.5 1.2 1.5 2.4 7.2 9.6 2.9 22.4 0.0 4.7 RBP1 "CRABP-I, CRBP, CRBP1, CRBPI, RBPC" ENSG00000114115 "Retinol binding protein 1" P09455 3 139517434-139539829 "Metabolic proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 1366.7;pancreas: 632.7" "Group enriched" "Detected in many" 4 "Granulosa cells: 5988.6;Theca cells: 3228.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "SH-SY5Y: 835.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 64.4" "HPA007338, CAB018603, CAB019276" Enhanced Approved Nucleoplasm,Cytosol NA NA 41000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Cytosol Nucleoplasm "CAB018603: AB_2060572, CAB019276: , HPA007338: AB_2667814" "unprognostic (9.62e-3)" "unprognostic (7.67e-2)" "unprognostic (9.53e-3)" "unprognostic (5.17e-1)" "unprognostic (7.48e-3)" "unprognostic (2.27e-2)" "unprognostic (6.29e-2)" "unprognostic (1.16e-1)" "unprognostic (7.12e-2)" "unprognostic (3.91e-3)" "unprognostic (2.74e-2)" "unprognostic (8.86e-2)" "unprognostic (1.11e-3)" "unprognostic (2.60e-2)" "unprognostic (1.71e-1)" "unprognostic (4.50e-2)" "unprognostic (1.28e-3)" 23.7 377.1 64.6 18.4 65.2 1.3 49.5 64.9 72.7 53.8 251.4 30.3 32.3 180.2 64.2 35.4 390.2 182.9 60.1 65.5 67.8 46.9 140.8 26.8 18.6 83.1 69.0 1366.7 632.7 46.8 257.8 63.6 64.7 44.8 14.2 23.2 50.2 41.3 15.2 31.3 26.2 119.3 68.2 47.0 29.3 56.1 75.2 9.4 23.0 15.5 12.0 65.7 24.3 67.5 7.8 2.9 7.4 164.2 0.3 0.0 0.9 0.1 0.0 0.0 0.1 0.4 76.1 0.0 53.8 0.1 2.6 0.1 38.2 0.5 0.0 0.1 5.3 0.1 2.7 75.5 155.1 0.2 0.1 3.0 0.0 0.1 0.0 160.9 0.0 0.0 0.2 29.9 0.2 0.0 0.2 0.5 18.4 0.2 0.0 0.1 32.0 0.5 0.1 0.1 19.6 835.4 35.3 0.1 0.1 13.9 3.2 1.1 0.0 0.3 120.0 0.2 0.3 0.6 0.5 0.5 1.3 0.0 2.3 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 64.6 65.2 64.9 72.7 65.5 67.8 83.1 69.0 64.7 68.2 75.2 67.5 24.8 32.1 5.9 8.8 3.5 17.6 53.5 91.9 2.8 26.3 70.4 47.8 21.4 77.2 30.3 23.9 2.1 3.2 1.0 0.1 13.7 1013.0 4.8 199.6 961.4 103.8 43.1 13.5 0.5 1042.7 6.2 158.8 19.9 58.1 0.0 5988.6 343.7 6.9 16.5 3.3 0.3 2.3 42.7 10.6 3.4 16.2 27.1 25.1 8.8 5.6 13.5 159.9 0.0 4.0 16.0 563.0 0.0 4.5 2.9 56.6 2.6 4.7 10.3 7.2 26.3 220.9 534.7 11.6 4.9 6.2 34.9 3.8 10.2 3228.5 2.7 32.7 RERG MGC15754 ENSG00000134533 "RAS like estrogen regulated growth inhibitor" Q96A58 12 15107783-15348675 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 104.7" "Cell type enhanced" "Detected in many" "Astrocytes: 202.7;Breast glandular cells: 80.1;Inhibitory neurons: 94.3;Sertoli cells: 92.1;Smooth muscle cells: 80.2" "Cancer enhanced" "Detected in all" "breast cancer: 19.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 15.2;BEWO: 34.1;T-47d: 66.0;U-2 OS: 21.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041387 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center" "HPA041387: AB_10796669" "unprognostic (5.33e-2)" "unprognostic (1.05e-1)" "unprognostic (7.72e-2)" "prognostic unfavorable (7.56e-4)" "unprognostic (8.72e-2)" "unprognostic (9.42e-3)" "unprognostic (2.47e-1)" "unprognostic (2.38e-2)" "unprognostic (1.85e-3)" "unprognostic (2.76e-2)" "unprognostic (5.07e-2)" "unprognostic (2.69e-1)" "unprognostic (7.16e-3)" "unprognostic (2.61e-3)" "unprognostic (3.30e-2)" "unprognostic (3.50e-1)" "unprognostic (2.58e-2)" 30.7 45.4 8.9 6.8 21.0 0.0 42.5 5.9 16.3 32.0 3.5 37.0 4.1 104.7 50.3 15.1 72.7 11.2 14.0 10.2 12.3 37.0 2.5 16.5 4.3 20.7 12.8 29.0 9.8 4.8 1.4 33.3 21.2 17.0 9.3 0.8 10.2 77.5 5.4 10.2 18.0 83.9 7.7 31.4 20.1 9.0 12.8 2.6 5.8 5.8 2.7 17.4 20.0 9.0 0.0 1.6 0.3 15.2 6.0 0.3 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 6.9 0.0 0.1 0.0 0.2 0.2 0.0 0.0 4.3 0.1 5.9 0.0 4.7 0.0 1.9 0.8 1.0 0.0 2.3 0.0 0.0 0.0 0.6 0.0 1.4 0.7 0.2 0.3 1.7 0.0 0.9 0.1 0.0 0.2 5.8 0.3 0.1 2.2 2.5 2.6 0.0 1.0 66.0 0.0 0.0 0.9 21.5 0.4 0.0 0.1 5.7 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 21.0 5.9 16.3 10.2 12.3 20.7 12.8 21.2 7.7 12.8 9.0 10.7 0.0 2.2 202.7 0.4 3.8 8.6 0.9 6.2 1.3 80.1 36.2 1.0 5.7 4.0 7.3 0.0 12.0 0.7 0.0 15.6 9.8 20.9 6.5 9.8 6.0 1.8 0.0 20.2 9.8 14.6 28.7 2.6 1.0 0.0 0.1 2.2 0.0 2.1 3.3 94.3 0.0 18.3 0.0 2.3 16.1 22.1 1.1 7.2 41.2 0.0 5.0 0.0 3.0 1.1 2.2 0.0 32.0 0.0 3.5 0.0 33.7 0.1 0.5 92.1 8.2 80.2 8.3 15.0 12.6 5.5 14.0 1.2 16.1 0.0 5.8 RFTN2 "C2orf11, FLJ30574, Raftlin-2" ENSG00000162944 "Raftlin family member 2" Q52LD8 2 197568224-197676045 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 70.9" "Group enriched" "Detected in many" 7 "Astrocytes: 152.8;Early spermatids: 125.0;Late spermatids: 351.7;Oligodendrocyte precursor cells: 198.5;Oligodendrocytes: 320.6" "Cancer enriched" "Detected in many" 5 "glioma: 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 19.8;ASC diff: 15.5;ASC TERT1: 8.7;HSkMC: 10.7;TIME: 6.4;WM-115: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035232, HPA043190" Approved Approved "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA035232: AB_10601495, HPA043190: " "unprognostic (1.15e-1)" "unprognostic (3.52e-1)" "unprognostic (2.07e-2)" "unprognostic (1.00e-1)" "prognostic favorable (8.05e-4)" "unprognostic (1.89e-2)" "unprognostic (1.81e-1)" "unprognostic (3.09e-2)" "unprognostic (2.16e-2)" "unprognostic (6.04e-2)" "unprognostic (1.39e-1)" "unprognostic (1.05e-1)" "unprognostic (8.44e-3)" "unprognostic (2.56e-2)" "unprognostic (1.01e-1)" "unprognostic (1.62e-1)" "unprognostic (6.77e-2)" 10.8 4.7 30.0 1.9 48.9 0.3 3.2 39.2 32.6 4.4 3.7 1.8 0.7 4.6 1.2 2.5 2.2 4.4 3.4 28.3 29.4 2.0 1.0 2.4 2.5 42.5 36.6 9.9 1.9 0.6 0.7 6.2 49.5 1.7 1.9 4.3 3.3 1.6 1.5 2.3 1.3 3.3 40.2 1.9 1.5 3.0 33.7 0.8 1.9 5.8 1.5 2.7 2.4 70.9 0.2 0.0 19.8 0.4 15.5 8.7 0.7 0.2 1.3 0.0 1.1 0.3 0.4 0.4 0.5 1.8 0.4 0.6 0.0 0.0 0.0 0.8 0.1 0.1 1.0 0.0 2.2 0.3 0.3 10.7 0.4 0.1 0.0 0.1 2.3 0.6 0.0 0.2 0.4 0.9 0.1 0.1 0.8 0.8 0.6 0.1 0.5 0.2 0.0 0.2 0.5 0.2 0.0 0.0 3.0 3.4 0.1 0.0 6.4 1.7 0.3 0.1 0.3 0.5 1.1 0.2 1.6 0.0 9.6 0.2 0.0 0.0 0.2 0.0 0.4 0.1 0.2 0.1 0.0 0.1 0.2 0.4 0.4 0.0 0.0 0.1 0.1 0.0 30.0 48.9 39.2 32.6 28.3 29.4 42.5 36.6 49.5 40.2 33.7 70.9 14.8 0.0 0.6 152.8 0.2 2.4 0.2 0.1 0.0 1.3 1.3 1.4 2.2 2.8 0.1 0.0 0.0 0.2 0.5 0.1 0.0 1.0 125.0 0.9 9.7 13.0 0.0 0.0 1.2 0.0 0.1 16.3 0.0 0.4 0.0 8.6 19.6 0.3 0.4 3.3 1.5 0.0 0.0 0.6 3.3 351.7 15.8 0.7 16.0 32.8 0.0 23.5 0.0 198.5 320.6 0.1 0.0 22.2 1.6 0.3 0.0 0.1 0.2 1.5 6.6 16.2 8.3 4.5 2.8 0.5 2.3 0.0 0.6 3.3 0.0 0.1 RUNX1T1 "AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2" ENSG00000079102 "RUNX1 partner transcriptional co-repressor 1" Q06455 8 91954967-92103286 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 93.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 142.1;Excitatory neurons: 196.9;Hepatic stellate cells: 124.2;Inhibitory neurons: 326.3;Oligodendrocyte precursor cells: 262.4" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in all" 7 "cerebellum: 93.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 19.6;fHDF/TERT166: 16.5;HEL: 35.9;HSkMC: 13.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049852, HPA070951" Approved Supported Nucleoplasm NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA049852: AB_2680914, HPA070951: AB_2686326" "unprognostic (2.37e-1)" "unprognostic (1.90e-1)" "unprognostic (1.90e-1)" "unprognostic (2.35e-1)" "unprognostic (1.62e-1)" "unprognostic (3.37e-4)" "unprognostic (2.29e-4)" "unprognostic (5.56e-3)" "unprognostic (1.24e-2)" "unprognostic (1.62e-2)" "unprognostic (2.11e-2)" "unprognostic (2.37e-1)" "unprognostic (5.70e-4)" "unprognostic (8.98e-3)" "unprognostic (6.78e-2)" "unprognostic (1.51e-1)" "unprognostic (7.80e-3)" 7.0 2.8 9.4 2.1 13.2 0.2 5.1 93.1 8.7 8.4 0.0 6.5 1.2 7.4 3.6 2.5 4.7 5.0 8.2 13.1 2.3 1.4 0.6 3.8 1.3 1.4 12.8 4.7 1.0 1.0 3.0 5.8 4.6 2.5 2.4 5.2 3.1 2.4 3.9 2.4 2.5 6.5 4.2 1.9 2.7 3.6 3.6 0.5 3.7 4.8 1.1 3.8 3.9 1.2 0.0 0.0 0.4 1.9 5.0 7.2 0.0 7.6 11.6 5.0 7.6 0.0 0.0 19.6 0.0 16.5 0.0 0.0 4.0 0.5 3.3 0.0 3.2 35.9 0.0 0.0 1.9 0.0 0.0 13.6 0.0 8.4 0.4 0.0 10.8 0.0 0.1 0.0 1.3 0.0 0.0 0.0 2.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 11.1 6.0 0.0 0.0 0.0 7.8 0.0 0.0 1.2 0.4 0.0 0.9 0.0 3.8 0.0 6.3 0.7 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 13.2 93.1 8.7 13.1 2.3 1.4 12.8 4.6 4.2 3.6 1.2 44.9 0.0 1.1 90.8 0.1 6.2 0.2 0.0 0.6 142.1 1.2 5.1 46.0 0.0 0.6 0.0 16.7 1.1 0.5 0.2 1.9 0.0 2.6 1.1 65.8 64.3 47.7 2.7 196.9 0.2 0.3 77.7 0.5 1.1 1.3 2.1 124.2 1.5 1.9 35.3 326.3 0.6 0.0 4.1 9.4 7.5 96.3 1.2 10.6 103.0 0.0 3.9 0.0 262.4 17.3 0.2 0.0 98.9 0.0 0.3 0.0 0.1 0.0 7.2 65.7 24.4 43.1 3.3 16.8 0.9 4.8 1.1 1.1 20.7 0.0 0.1 SEMA5B "FLJ10372, KIAA1445, SEMAG, SemG" ENSG00000082684 "Semaphorin 5B" Q9P283 3 122909082-123028605 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.2" "Cell type enhanced" "Detected in some" "Astrocytes: 9.4;Excitatory neurons: 30.8;Muller glia cells: 7.3;Oligodendrocyte precursor cells: 45.2;Smooth muscle cells: 14.3" "Cancer enhanced" "Detected in many" "renal cancer: 18.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 79.7;NTERA-2: 15.7;SH-SY5Y: 21.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066548 Enhanced Supported Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA066548: AB_2685689" "unprognostic (7.34e-2)" "unprognostic (1.84e-3)" "unprognostic (1.92e-4)" "unprognostic (3.01e-2)" "unprognostic (1.04e-1)" "unprognostic (2.28e-1)" "unprognostic (4.72e-2)" "unprognostic (1.58e-2)" "unprognostic (7.66e-3)" "unprognostic (2.87e-2)" "unprognostic (4.71e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (7.57e-4)" "unprognostic (1.31e-3)" "unprognostic (5.96e-2)" "unprognostic (6.12e-2)" "unprognostic (2.12e-1)" 1.7 1.5 12.1 0.4 11.8 0.0 1.3 7.3 15.9 1.8 6.7 1.3 0.9 1.4 2.8 0.7 3.5 2.5 9.5 16.2 8.0 9.1 0.9 1.2 0.6 8.4 8.5 1.4 1.7 0.6 2.7 2.6 9.7 1.4 0.8 7.1 0.4 1.4 0.9 1.5 1.5 1.9 7.7 0.2 0.6 0.7 7.8 0.2 2.6 0.5 0.6 1.6 1.6 10.9 0.0 0.0 79.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.3 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 15.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 21.3 0.0 0.2 0.0 3.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 11.8 7.3 15.9 16.2 8.0 8.4 8.5 9.7 7.7 7.8 10.9 1.2 0.0 1.1 9.4 0.0 0.0 0.0 0.1 0.0 7.2 0.1 0.0 3.5 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.8 0.0 0.0 30.8 0.0 0.3 0.7 0.0 0.0 0.0 0.1 1.8 0.0 0.1 0.0 6.6 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.9 0.6 7.3 0.0 45.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.1 14.3 0.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 SEMA6D "FLJ11598, KIAA1479" ENSG00000137872 "Semaphorin 6D" Q8NFY4 15 47184101-47774228 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.5;placenta: 43.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 114.7;Excitatory neurons: 120.7;Horizontal cells: 79.1;Inhibitory neurons: 319.5;Oligodendrocytes: 140.1" "Cancer enriched" "Detected in many" 4 "glioma: 8.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 14.9;SCLC-21H: 13.3;SH-SY5Y: 12.1;SuSa: 14.2;U-266/70: 10.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043109 Approved "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA 1100000 "Cluster 45: Intestine - Brush border" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Golgi apparatus" "HPA043109: AB_10793941" "unprognostic (2.00e-1)" "unprognostic (4.62e-2)" "unprognostic (3.10e-2)" "unprognostic (3.83e-3)" "unprognostic (1.38e-1)" "unprognostic (3.85e-2)" "unprognostic (1.98e-1)" "unprognostic (2.17e-3)" "unprognostic (1.24e-1)" "unprognostic (5.36e-2)" "unprognostic (7.96e-4)" "unprognostic (1.42e-1)" "prognostic favorable (5.96e-5)" "unprognostic (3.74e-2)" "unprognostic (8.56e-2)" "unprognostic (3.30e-3)" "unprognostic (2.39e-4)" 5.5 1.5 11.3 3.9 27.9 0.4 5.0 11.1 21.3 5.8 0.0 10.6 21.8 1.6 2.5 1.7 4.9 4.0 9.4 9.8 16.3 15.1 3.1 8.9 2.1 17.2 31.1 26.7 16.1 10.6 5.5 43.1 23.1 4.5 12.7 15.8 4.5 8.4 20.9 3.0 38.5 3.3 12.0 2.5 3.0 2.6 20.5 2.7 5.8 6.0 0.6 3.1 10.0 28.8 0.0 0.0 2.5 0.0 1.5 1.2 0.2 0.6 14.9 0.4 0.0 0.3 0.1 2.2 0.0 4.0 0.0 7.6 3.4 1.1 0.1 1.1 1.7 0.0 5.0 0.0 4.0 0.0 0.2 1.1 8.3 0.0 0.5 0.0 1.0 5.7 0.1 3.4 0.4 0.8 2.8 0.7 4.6 0.0 0.0 1.6 0.1 2.4 1.1 1.1 13.3 12.1 0.1 1.0 4.3 14.2 0.5 0.0 0.0 6.9 0.3 0.2 0.0 10.0 0.0 2.3 1.8 0.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 11.3 27.9 11.1 21.3 9.8 16.3 17.2 31.1 23.1 12.0 20.5 28.8 13.9 51.3 1.5 72.8 0.2 2.0 4.0 1.4 1.2 6.2 0.5 10.7 10.0 4.3 2.1 11.0 114.7 19.7 0.1 40.6 5.9 1.0 0.2 0.5 2.3 10.1 17.4 0.0 120.7 0.2 1.8 10.8 0.0 0.3 3.8 71.0 5.0 0.9 2.6 79.1 319.5 5.4 0.0 0.0 1.9 1.2 23.3 1.0 8.8 15.9 0.0 9.3 0.0 43.2 140.1 0.3 8.5 13.5 0.0 1.2 53.5 0.2 0.1 2.3 0.0 9.3 13.9 0.8 6.3 0.3 1.1 4.7 0.2 3.4 15.1 1.6 SLC7A4 "CAT-4, HCAT3, VH" ENSG00000099960 "Solute carrier family 7 member 4" O43246 22 21028718-21032840 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 15.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 21.2;Endometrial ciliated cells: 16.4;Glandular and luminal cells: 32.0;Intestinal goblet cells: 8.9;Ionocytes: 12.2;Syncytiotrophoblasts: 10.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 21 "BEWO: 140.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA031023 Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" "HPA031023: AB_10669669" "unprognostic (1.02e-3)" "unprognostic (4.34e-2)" "unprognostic (6.75e-2)" "unprognostic (1.27e-1)" "unprognostic (3.82e-2)" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (3.91e-2)" "unprognostic (3.68e-2)" "unprognostic (2.51e-2)" "unprognostic (2.58e-2)" "unprognostic (1.21e-3)" "unprognostic (9.69e-2)" "unprognostic (2.87e-1)" "unprognostic (1.62e-1)" "unprognostic (1.32e-2)" "unprognostic (4.00e-3)" 2.7 2.6 3.1 0.2 2.6 0.0 1.0 3.8 2.8 1.5 4.5 1.1 1.0 1.0 0.3 5.6 1.1 1.3 1.1 2.3 3.8 0.4 0.3 0.8 0.3 1.8 2.6 0.3 0.2 0.5 4.7 3.3 4.5 2.5 0.9 0.3 2.2 3.2 0.4 1.6 1.2 0.3 0.3 0.5 1.4 15.4 4.8 0.3 0.0 0.0 0.5 1.1 0.6 0.7 0.0 0.0 0.0 0.1 0.0 0.0 140.5 0.0 0.0 0.3 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.5 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 1.6 0.0 0.0 0.0 1.3 0.5 0.3 0.0 0.1 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.2 3.1 2.6 3.8 2.8 2.3 3.8 1.8 2.6 4.5 0.3 4.8 0.7 0.0 6.4 1.9 0.3 0.0 0.0 0.3 7.4 0.6 0.5 0.7 0.6 0.3 1.5 3.1 0.0 0.0 21.2 0.0 0.5 0.0 0.0 0.3 16.4 2.1 0.3 1.2 0.0 1.4 0.4 7.7 2.0 1.1 32.0 4.5 0.7 1.1 0.0 1.4 0.0 0.8 8.9 12.2 0.0 0.0 1.8 1.8 0.1 0.0 1.0 0.0 2.0 0.0 0.0 0.1 0.8 0.3 0.7 0.0 0.5 0.3 0.0 2.6 0.1 0.0 0.3 0.4 0.3 1.5 1.8 0.0 10.1 0.7 0.0 0.6 0.6 SLIT2 "SLIL3, Slit-2" ENSG00000145147 "Slit guidance ligand 2" O94813 4 20251905-20620561 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Excitatory neurons: 256.7;Inhibitory neurons: 544.9;Oligodendrocytes: 157.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 98.0;BJ hTERT+: 200.8;BJ hTERT+ SV40 Large T+: 97.8;fHDF/TERT166: 117.8;HBF TERT88: 112.0;HEK 293: 88.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007590, HPA019511, HPA023088" Uncertain "Secreted in other tissues" NA NA 77000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB007590: , HPA019511: AB_1857226, HPA023088: AB_1857227" "unprognostic (1.44e-1)" "unprognostic (4.54e-2)" "unprognostic (3.26e-2)" "unprognostic (6.13e-2)" "unprognostic (9.01e-3)" "unprognostic (6.49e-2)" "unprognostic (1.71e-1)" "unprognostic (4.78e-2)" "unprognostic (1.73e-1)" "unprognostic (6.16e-3)" "unprognostic (5.32e-2)" "unprognostic (4.30e-2)" "prognostic favorable (6.51e-4)" "unprognostic (4.93e-3)" "unprognostic (6.80e-3)" "unprognostic (1.74e-1)" "unprognostic (7.16e-4)" 8.0 24.9 3.2 3.3 6.4 0.0 9.4 0.0 14.0 24.0 11.7 11.5 2.4 16.4 9.9 5.8 13.1 9.4 7.8 6.6 20.5 12.3 2.0 34.9 1.8 7.9 3.1 4.3 2.8 1.5 8.8 25.2 4.5 12.6 5.4 13.2 6.1 15.7 2.9 3.8 4.8 24.9 0.4 14.2 9.0 1.3 17.6 2.4 9.2 5.1 1.2 13.1 13.9 2.4 0.1 0.0 54.6 0.0 37.8 34.8 1.7 98.0 200.8 97.8 36.9 0.4 0.1 0.0 3.4 117.8 0.2 1.2 15.7 7.9 112.0 0.2 88.3 0.0 0.4 0.0 7.2 0.9 0.0 8.5 0.0 63.6 18.6 2.1 35.0 0.0 0.0 0.0 4.6 0.0 0.0 0.4 1.7 0.0 6.3 61.2 0.5 0.0 1.0 0.1 3.5 0.8 0.0 0.2 0.4 1.9 0.2 0.2 2.0 34.9 5.0 35.0 54.2 0.0 0.1 0.0 0.9 0.0 19.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 6.4 0.0 14.0 6.6 20.5 7.9 3.1 4.5 0.4 17.6 2.4 1.6 0.0 9.0 10.1 0.0 8.0 2.0 0.1 0.6 47.6 1.0 0.6 5.2 1.5 1.3 0.0 0.0 1.1 0.0 0.6 1.9 1.7 0.6 6.4 1.9 2.0 1.2 0.0 256.7 0.5 1.2 58.8 0.0 7.1 2.5 1.3 4.2 0.2 1.9 0.0 544.9 0.0 0.0 1.0 9.7 1.7 26.4 0.7 8.8 31.9 0.0 1.3 0.0 43.7 157.9 0.2 0.0 26.7 0.1 3.7 0.0 11.5 7.4 2.1 6.6 3.2 6.4 0.2 1.7 1.2 6.7 2.1 1.1 20.3 0.1 1.9 SLIT3 "MEGF5, SLIL2, Slit-3, SLIT1, slit2" ENSG00000184347 "Slit guidance ligand 3" O75094 5 168661733-169301139 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 202.3;Fibroblasts: 112.7;Sertoli cells: 85.5;Smooth muscle cells: 99.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 12.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Cell line enhanced" "Detected in many" "ASC diff: 310.3;fHDF/TERT166: 116.0;RT4: 101.1;SH-SY5Y: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051630 Approved Supported "Cell Junctions" "Secreted in other tissues" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Cell Junctions" "HPA051630: AB_2681557" "unprognostic (2.86e-2)" "unprognostic (2.64e-1)" "unprognostic (4.43e-2)" "unprognostic (2.92e-2)" "unprognostic (2.50e-2)" "unprognostic (3.53e-2)" "unprognostic (9.21e-3)" "unprognostic (3.06e-2)" "unprognostic (1.71e-1)" "unprognostic (9.50e-3)" "unprognostic (1.57e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.45e-5)" "unprognostic (5.90e-3)" "unprognostic (8.56e-2)" "unprognostic (4.27e-1)" "unprognostic (3.53e-1)" 61.9 20.7 10.0 11.9 10.6 0.1 32.7 11.9 7.5 36.4 0.3 20.0 5.4 23.9 8.8 21.4 22.2 43.5 39.7 12.3 4.3 16.7 1.5 38.1 6.2 12.9 0.7 17.0 7.8 44.9 4.4 21.7 11.6 10.3 9.7 3.1 16.8 15.4 4.4 25.8 10.4 27.1 0.3 14.3 10.1 2.7 6.9 20.0 23.3 6.5 4.2 55.5 24.3 2.2 0.0 11.0 0.1 0.0 310.3 5.7 0.0 18.1 3.1 4.0 8.4 0.1 0.0 0.0 4.2 116.0 13.1 0.0 2.9 1.2 0.3 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 1.8 4.2 0.5 3.9 44.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 101.1 1.1 73.3 0.0 0.0 0.0 12.5 0.0 0.0 0.0 3.0 1.9 25.5 0.1 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 10.0 10.6 11.9 7.5 12.3 4.3 12.9 0.7 11.6 0.3 6.9 2.2 11.7 0.0 2.3 4.2 0.5 26.6 1.8 5.5 3.4 8.6 1.1 3.8 25.9 0.0 0.4 0.0 0.0 2.3 0.5 0.0 0.0 0.2 11.9 1.3 35.7 5.4 0.0 0.0 202.3 0.0 0.5 112.7 4.6 3.6 1.3 0.5 1.8 0.0 1.2 0.0 20.2 0.0 0.0 0.0 32.5 8.2 0.9 1.1 35.6 14.0 0.0 13.7 0.0 8.0 2.9 0.0 0.0 0.4 0.8 1.1 0.1 1.9 0.2 0.9 85.5 1.8 99.3 1.2 2.2 1.1 17.6 1.1 1.8 0.3 0.0 0.8 SPRY1 hSPRY1 ENSG00000164056 "Sprouty RTK signaling antagonist 1" O43609 4 123396795-123403760 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 238.1" "Cell type enhanced" "Detected in many" "Adipocytes: 771.3;Endothelial cells: 352.8;Fibroblasts: 222.3;Leydig cells: 448.0;Skeletal myocytes: 245.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 61.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 95.4;AN3-CA: 194.1;ASC diff: 76.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013538, HPA051369, HPA070554" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Cytosol" Nucleoplasm "CAB013538: AB_2533452, HPA051369: AB_2681457, HPA070554: AB_2686280" "unprognostic (1.27e-1)" "unprognostic (9.08e-2)" "unprognostic (2.06e-1)" "unprognostic (7.15e-2)" "unprognostic (5.33e-2)" "unprognostic (2.19e-2)" "unprognostic (1.36e-1)" "unprognostic (9.43e-2)" "unprognostic (6.99e-2)" "unprognostic (4.32e-1)" "unprognostic (4.06e-1)" "unprognostic (3.11e-2)" "unprognostic (8.77e-3)" "unprognostic (1.21e-3)" "unprognostic (4.48e-2)" "unprognostic (1.54e-2)" "unprognostic (1.27e-1)" 238.1 38.4 6.5 22.3 7.9 22.7 154.3 7.6 9.0 71.9 26.6 46.6 15.7 40.9 24.1 42.5 81.2 83.8 73.1 7.5 8.4 35.6 21.5 58.3 13.0 5.5 5.4 30.0 31.8 37.4 27.3 49.6 5.8 52.0 27.5 19.0 45.2 24.7 49.9 79.8 25.2 57.7 5.6 17.0 35.1 10.2 7.6 29.2 92.7 49.9 10.1 74.4 71.0 6.0 6.3 1.8 95.4 194.1 76.5 51.6 6.4 0.4 4.9 0.3 2.0 5.8 10.3 0.0 42.4 2.9 0.4 1.2 2.6 4.6 0.7 0.1 10.0 2.2 0.0 31.0 21.7 14.2 0.1 21.1 2.5 0.7 2.1 10.5 8.1 2.2 1.7 1.9 4.7 0.7 16.4 34.8 22.8 22.6 32.0 7.1 10.3 0.2 13.2 14.5 14.5 12.3 0.1 19.4 19.6 10.1 1.9 0.0 20.2 1.2 0.2 0.4 2.9 1.0 0.1 0.2 1.4 2.6 3.2 0.1 0.4 6.5 1.1 0.2 33.1 29.8 4.0 9.2 0.1 61.2 5.7 6.4 0.4 14.2 0.1 1.7 0.0 2.0 6.5 7.9 7.6 9.0 7.5 8.4 5.5 5.4 5.8 5.6 7.6 6.0 771.3 28.9 28.3 14.4 16.2 49.6 17.3 37.3 68.9 86.2 22.8 69.6 16.9 32.9 20.6 27.6 33.3 12.7 21.6 10.4 80.3 5.0 2.5 45.9 41.9 352.8 26.5 5.7 5.0 10.9 1.7 222.3 8.2 67.4 9.5 0.2 166.3 5.9 10.1 6.7 2.2 15.0 14.2 15.3 37.9 10.5 448.0 17.1 46.2 5.6 0.7 158.3 0.0 7.5 0.3 7.0 6.3 57.9 6.1 16.8 8.1 38.7 11.7 84.5 151.2 245.0 81.6 6.2 9.6 37.0 43.3 3.1 57.3 1.8 17.9 13.5 STAC STAC1 ENSG00000144681 "SH3 and cysteine rich domain" Q99469 3 36380503-36548007 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 13.8" "Cell type enhanced" "Detected in some" "Distal tubular cells: 5.9;Early spermatids: 5.2;granulocytes: 6.3;Granulosa cells: 12.5;Late spermatids: 5.3;Muller glia cells: 21.6;Smooth muscle cells: 5.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 1.5;NK-cell: 1.3;T-reg: 1.5" "Group enriched" "Detected in many" 5 "granulocytes: 1.5;NK-cells: 1.3;T-cells: 1.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 46.8;HaCaT: 34.1;SH-SY5Y: 49.1;U-251 MG: 30.3;U-87 MG: 48.1" "Low region specificity" "Detected in many" HPA035143 Uncertain Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA035143: AB_10603892" "unprognostic (5.29e-2)" "unprognostic (7.61e-2)" "unprognostic (2.58e-1)" "unprognostic (1.44e-6)" "unprognostic (4.24e-2)" "unprognostic (1.83e-2)" "unprognostic (3.06e-2)" "unprognostic (3.89e-1)" "unprognostic (2.02e-1)" "unprognostic (3.31e-3)" "unprognostic (1.77e-3)" "unprognostic (5.82e-2)" "unprognostic (8.07e-2)" "unprognostic (1.73e-4)" "unprognostic (8.93e-2)" "unprognostic (1.95e-1)" "unprognostic (7.94e-3)" 2.8 5.1 1.4 0.6 1.9 0.4 1.9 3.6 3.9 7.0 5.0 3.6 0.1 1.4 0.3 2.1 3.2 2.7 0.7 0.8 4.3 2.5 0.9 11.1 0.4 2.3 2.5 2.5 0.1 10.1 1.1 0.3 6.9 13.8 0.7 5.8 1.3 4.4 1.6 1.2 0.4 3.4 1.9 0.6 0.9 1.9 2.1 0.7 0.5 5.3 0.2 3.7 2.2 0.5 7.7 3.3 1.6 0.0 6.5 2.1 0.1 19.9 0.4 4.0 4.6 0.0 0.0 0.0 7.8 46.8 13.0 34.1 2.4 8.2 4.1 0.0 7.2 1.1 10.0 0.2 0.0 20.3 0.4 2.4 0.2 0.1 0.7 27.6 0.0 1.8 0.0 0.4 0.5 0.0 4.1 0.2 13.8 0.0 3.0 0.0 0.0 0.0 10.8 0.0 6.2 49.1 7.9 5.2 0.1 13.6 0.0 2.0 8.5 0.5 19.1 0.6 30.3 0.0 0.0 0.0 48.1 7.9 8.3 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1.5 0.0 1.4 1.9 3.6 3.9 0.8 4.3 2.3 2.5 6.9 1.9 2.1 0.5 0.9 0.0 0.5 0.3 0.0 0.0 0.0 0.5 0.0 0.7 2.3 0.8 0.9 0.0 1.3 0.0 0.0 0.0 0.1 0.0 5.9 0.2 5.2 0.9 0.5 0.4 0.0 2.1 0.6 0.0 0.1 1.5 0.0 2.1 6.3 12.5 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 2.2 5.3 0.0 4.8 0.0 0.0 0.0 21.6 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.4 5.0 1.8 0.1 0.0 0.3 0.0 0.4 0.0 0.0 0.0 STK32A "MGC22688, YANK1" ENSG00000169302 "Serine/threonine kinase 32A" Q8WU08 5 147234963-147387855 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 11.2;brain: 24.4" "Cell type enriched" "Detected in many" 19 "Oligodendrocyte precursor cells: 306.6" "Group enriched" "Detected in many" 5 "glioma: 4.3;melanoma: 11.9;thyroid cancer: 9.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "RT4: 13.6;SK-MEL-30: 48.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040236 Approved Centrosome NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" Centrosome "HPA040236: AB_10795416" "unprognostic (1.90e-1)" "unprognostic (4.71e-4)" "unprognostic (5.32e-2)" "unprognostic (3.49e-2)" "unprognostic (7.62e-2)" "unprognostic (6.82e-2)" "unprognostic (2.66e-2)" "unprognostic (2.96e-3)" "unprognostic (4.85e-2)" "unprognostic (2.36e-2)" "unprognostic (3.87e-1)" "unprognostic (8.38e-2)" "unprognostic (2.50e-3)" "unprognostic (5.53e-5)" "unprognostic (2.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.67e-3)" 1.3 11.2 5.9 0.6 9.5 0.0 1.2 13.2 3.1 1.0 1.0 2.3 0.5 0.5 2.6 0.3 0.8 1.5 1.0 3.5 14.4 3.4 0.1 1.2 0.0 11.7 24.4 2.5 2.6 0.1 8.1 0.1 17.0 1.0 0.3 2.6 0.9 0.8 0.2 3.7 0.7 0.4 10.4 0.3 1.2 1.0 14.0 0.1 8.7 0.5 0.0 1.7 1.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.5 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.5 0.0 1.1 0.0 0.0 0.2 4.4 13.6 1.2 0.5 0.0 0.0 48.6 0.2 0.0 0.0 0.1 0.0 0.5 0.7 0.4 1.0 0.2 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 9.5 13.2 3.1 3.5 14.4 11.7 24.4 17.0 10.4 14.0 10.1 0.2 0.0 2.6 8.5 0.0 1.5 0.2 1.4 0.0 1.8 1.3 0.5 0.5 0.0 1.0 1.8 0.0 0.0 0.0 0.1 1.9 1.8 6.9 0.2 0.5 0.1 0.0 0.0 4.6 2.7 0.0 2.7 0.0 0.7 0.0 4.2 0.0 0.0 0.1 0.0 5.2 0.0 2.0 0.0 1.0 10.5 0.9 0.2 16.0 0.0 0.0 4.0 0.0 306.6 0.7 5.5 0.0 4.1 0.0 0.3 0.0 4.1 0.2 1.0 0.0 5.4 0.5 0.0 0.1 0.0 0.3 0.1 0.1 1.4 0.0 0.6 STON1 "SBLF, stoned-b1" ENSG00000243244 "Stonin 1" Q9Y6Q2 2 48529383-48598513 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.0;Muller glia cells: 33.4;Sertoli cells: 26.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 1.9;neutrophil: 1.0" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "ASC diff: 23.7;ASC TERT1: 28.6;HSkMC: 36.1;hTERT-RPE1: 17.0;SuSa: 19.6" "Low region specificity" "Detected in all" HPA005715 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "HPA005715: AB_1080113" "unprognostic (1.61e-1)" "unprognostic (4.44e-1)" "unprognostic (7.97e-2)" "unprognostic (1.02e-4)" "unprognostic (1.54e-1)" "unprognostic (2.11e-1)" "unprognostic (1.35e-1)" "unprognostic (3.01e-2)" "unprognostic (8.99e-3)" "unprognostic (1.09e-1)" "unprognostic (1.76e-1)" "unprognostic (2.10e-2)" "prognostic unfavorable (4.69e-4)" "unprognostic (1.06e-2)" "unprognostic (2.50e-1)" "unprognostic (8.68e-2)" "unprognostic (2.49e-3)" 20.8 5.2 2.3 5.7 2.8 0.5 10.9 10.5 2.0 10.5 10.7 34.5 3.6 27.4 4.6 16.0 17.2 15.6 6.4 1.9 7.1 9.3 2.1 10.9 2.8 33.2 12.5 24.5 1.9 2.1 2.8 18.4 25.9 21.7 8.4 18.1 2.5 19.3 2.2 4.1 7.9 25.1 25.6 7.4 13.0 1.1 4.1 2.5 4.6 6.3 1.4 22.2 10.5 29.2 0.1 0.0 8.6 0.1 23.7 28.6 4.9 1.0 9.2 0.9 2.1 0.1 0.0 0.0 0.3 12.0 4.6 9.0 8.3 0.3 1.7 0.1 2.3 1.4 0.6 0.0 13.5 0.0 0.4 36.1 1.7 2.5 1.0 17.0 16.4 0.8 0.2 0.2 5.7 0.5 0.7 0.3 8.0 0.0 0.1 1.3 1.7 0.0 0.9 6.6 0.3 1.9 0.7 1.5 4.0 19.6 0.7 0.3 8.8 3.0 2.3 0.0 0.7 0.5 0.1 0.0 1.6 0.1 1.9 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.3 2.8 10.5 2.0 1.9 7.1 33.2 12.5 25.9 25.6 4.1 29.2 16.4 0.0 0.5 0.0 1.1 2.4 15.4 1.1 16.5 3.8 0.8 1.8 2.3 0.0 0.8 5.5 2.1 15.1 0.5 0.6 3.9 0.8 0.4 1.9 42.0 7.7 2.4 0.0 0.0 0.4 1.0 9.9 0.5 2.6 0.0 3.9 11.4 0.2 2.7 13.5 0.0 0.3 0.0 1.3 2.8 0.9 12.2 1.6 0.0 0.0 1.2 33.4 1.0 0.0 0.0 0.4 0.3 10.1 0.2 13.8 0.4 2.0 0.6 2.3 26.3 1.9 15.1 0.3 1.7 1.9 2.4 12.6 1.5 2.6 0.9 14.3 SUSD2 "BK65A6.2, FLJ22778, W5C5" ENSG00000099994 "Sushi domain containing 2" Q9UGT4 22 24181487-24189106 "Predicted membrane proteins" Receptor "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 99.8" "Group enriched" "Detected in many" 6 "Alveolar cells type 1: 250.0;Alveolar cells type 2: 151.5;Proximal enterocytes: 154.9" "Cancer enhanced" "Detected in all" "testis cancer: 64.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 29 "SK-BR-3: 898.7" "Low region specificity" "Detected in all" HPA004117 Enhanced Approved "Plasma membrane" NA NA 6800000 "Cluster 19: Lung - Lung function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "HPA004117: AB_1857674" "unprognostic (5.24e-3)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "unprognostic (7.30e-2)" "unprognostic (1.27e-2)" "unprognostic (5.40e-2)" "unprognostic (5.20e-2)" "unprognostic (1.89e-2)" "unprognostic (5.87e-2)" "unprognostic (1.20e-2)" "unprognostic (9.74e-3)" "unprognostic (8.97e-2)" "prognostic unfavorable (3.29e-5)" "unprognostic (2.72e-2)" "unprognostic (2.82e-2)" "unprognostic (1.88e-2)" "unprognostic (3.33e-3)" 12.1 9.6 4.9 1.9 2.8 0.2 9.5 1.7 5.8 13.6 2.2 4.8 12.8 9.8 0.5 2.8 15.0 1.8 12.5 1.6 5.3 32.6 2.9 99.8 2.2 22.9 6.9 5.4 4.3 1.5 7.1 3.6 26.5 5.6 1.0 0.1 4.7 5.6 2.2 28.2 34.6 3.4 6.8 3.6 6.3 3.2 13.2 0.8 17.8 1.4 1.3 5.4 11.0 10.0 5.1 10.4 0.1 0.0 18.8 24.3 0.8 2.4 0.1 0.1 0.0 7.8 0.6 1.4 21.5 0.5 0.4 1.4 0.1 0.5 0.0 0.6 0.3 0.0 0.4 30.6 8.0 0.0 0.3 21.5 0.4 0.1 6.2 0.0 0.1 0.0 0.5 0.3 0.0 9.1 0.3 0.4 0.7 2.5 0.3 0.3 0.0 2.5 0.1 0.2 1.7 13.5 0.7 898.7 0.2 3.6 3.0 0.0 0.0 0.1 0.9 0.7 0.1 1.1 1.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 2.8 1.7 5.8 1.6 5.3 22.9 6.9 26.5 6.8 13.2 10.0 1.7 250.0 151.5 0.3 0.6 0.3 0.3 2.6 0.0 0.0 3.4 3.4 6.8 0.0 20.9 1.8 0.0 13.8 0.3 0.7 5.9 0.1 0.0 1.3 0.7 1.1 1.8 0.0 0.2 0.0 0.7 6.7 0.5 1.3 3.8 0.1 2.9 0.5 1.1 0.0 0.1 5.5 2.0 0.0 0.3 0.4 0.6 0.8 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.4 154.9 27.8 3.6 0.0 0.0 0.6 22.1 1.7 1.3 0.7 2.7 26.4 1.1 0.0 1.6 0.6 THY1 CD90 ENSG00000154096 "Thy-1 cell surface antigen" P04216 11 119415476-119424985 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 286.8;smooth muscle: 304.7;urinary bladder: 216.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 141.6;Excitatory neurons: 116.0;Fibroblasts: 201.9;Inhibitory neurons: 104.1;Muller glia cells: 108.1;Proximal tubular cells: 199.9;Smooth muscle cells: 226.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 461.3;BJ: 738.4;BJ hTERT+: 832.5;fHDF/TERT166: 1330.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003733, CAB068243, CAB068244" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 14000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane" "CAB068243: AB_2665687, CAB068244: AB_2665688, HPA003733: AB_1846340" "unprognostic (9.98e-2)" "unprognostic (2.71e-1)" "unprognostic (5.13e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (6.87e-4)" "unprognostic (7.43e-2)" "unprognostic (1.43e-3)" "unprognostic (2.38e-2)" "unprognostic (1.29e-1)" "unprognostic (2.90e-3)" "unprognostic (3.38e-2)" "unprognostic (3.52e-1)" "prognostic unfavorable (2.40e-6)" "unprognostic (1.75e-2)" "unprognostic (1.90e-2)" "unprognostic (3.03e-2)" "unprognostic (1.14e-2)" 90.6 16.4 97.9 78.6 114.8 0.2 25.6 12.9 286.8 78.9 0.0 35.4 10.2 58.6 27.8 29.4 23.1 101.0 12.9 135.4 73.3 142.2 7.4 21.6 40.4 83.6 37.0 9.2 14.8 39.4 18.1 62.0 60.8 15.5 41.8 25.3 8.5 47.0 3.4 13.9 14.5 304.7 35.4 21.9 17.4 11.4 43.6 73.2 37.9 8.3 35.6 216.7 21.7 108.7 0.7 3.9 108.5 0.1 461.3 331.5 0.3 738.4 832.5 263.6 289.3 0.2 0.2 0.4 0.1 1330.6 121.9 0.9 4.3 1.1 200.7 65.1 0.0 41.5 14.4 0.0 142.7 0.0 0.2 247.5 0.0 335.6 11.6 355.2 0.3 22.6 0.0 0.6 206.5 0.1 0.6 0.1 173.9 0.0 1.4 0.5 50.7 0.3 0.1 0.2 18.1 47.9 0.1 0.4 0.2 32.9 1.0 2.1 0.0 368.6 120.9 107.3 110.1 0.3 19.7 0.4 1.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 97.9 114.8 12.9 286.8 135.4 73.3 83.6 37.0 60.8 35.4 43.6 108.7 68.2 0.0 1.8 17.3 2.1 17.7 0.3 1.7 0.0 27.2 1.6 40.0 0.9 0.0 0.0 9.2 0.0 1.9 0.2 0.0 21.5 0.9 1.0 5.1 141.6 69.2 0.0 0.0 116.0 0.0 2.6 201.9 1.5 3.2 1.3 0.0 17.5 0.1 4.0 32.0 104.1 0.0 0.0 0.0 25.0 2.7 96.3 2.7 17.8 21.5 0.0 108.1 0.0 64.3 22.7 0.4 0.0 77.5 0.1 0.3 0.0 199.9 0.0 27.5 32.9 9.3 226.6 0.3 0.6 0.2 17.6 4.0 4.5 6.2 0.0 0.6 TIMP2 CSC-21K ENSG00000035862 "TIMP metallopeptidase inhibitor 2" P16035 17 78852977-78925387 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 941.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 475.9;Late spermatids: 491.0;Leydig cells: 353.6;Peritubular cells: 770.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.6" "Group enriched" "Detected in many" 4 "granulocytes: 13.6;monocytes: 5.0" "Cell line enhanced" "Detected in many" "ASC diff: 1327.4;ASC TERT1: 1618.4;BJ hTERT+: 960.2;fHDF/TERT166: 1070.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010203 Approved "Secreted to extracellular matrix" NA NA 110000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB010203: AB_2204966" "unprognostic (1.03e-1)" "unprognostic (1.71e-2)" "unprognostic (9.81e-2)" "unprognostic (1.76e-3)" "unprognostic (3.24e-2)" "unprognostic (3.05e-1)" "unprognostic (4.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (4.73e-2)" "unprognostic (3.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.38e-3)" "unprognostic (4.62e-2)" "unprognostic (2.05e-1)" "unprognostic (2.77e-3)" 461.0 185.1 171.5 92.3 140.8 20.1 290.6 110.6 122.1 576.3 117.9 280.5 71.0 525.4 116.8 176.0 272.7 397.9 244.8 128.6 157.0 120.7 62.8 231.7 77.7 157.4 161.5 941.0 79.1 64.0 103.6 218.1 156.2 196.2 107.6 43.5 107.2 267.5 56.6 245.2 149.5 381.6 141.5 172.0 140.9 150.4 178.0 80.0 155.6 119.8 38.7 261.2 331.0 168.1 170.0 84.0 93.0 178.8 1327.4 1618.4 50.2 585.0 960.2 280.1 221.1 30.8 288.6 0.2 200.8 1070.2 307.4 32.9 29.1 25.2 291.4 3.4 16.6 0.1 156.0 48.1 392.7 2.6 1.2 641.1 12.0 276.8 44.3 722.5 375.9 54.4 0.2 0.5 292.5 19.5 176.8 29.7 16.6 34.2 122.8 118.0 213.2 73.4 178.7 2.3 47.6 290.3 366.6 170.8 776.3 111.6 86.8 42.2 450.3 744.2 140.5 438.0 102.8 84.1 74.9 1.5 171.0 32.0 367.6 0.0 5.0 7.4 0.0 3.4 0.0 0.1 0.1 0.0 2.2 0.2 0.2 0.3 13.6 0.2 4.3 1.4 0.1 0.9 171.5 140.8 110.6 122.1 128.6 157.0 157.4 161.5 156.2 141.5 178.0 168.1 147.9 112.2 34.3 24.2 18.7 98.9 9.0 5.7 9.1 37.5 9.7 37.6 41.9 52.9 20.8 25.8 8.4 4.3 6.1 46.0 0.0 78.0 143.7 17.0 190.3 115.0 7.8 12.4 9.8 22.0 87.7 475.9 17.9 24.4 7.0 97.5 259.5 7.9 208.8 3.3 107.7 14.3 12.2 177.4 171.4 491.0 353.6 184.8 275.7 96.5 87.3 39.9 5.2 60.8 143.5 83.3 6.0 770.7 33.1 10.1 12.8 0.8 5.4 12.7 92.1 111.8 171.9 8.5 7.7 5.6 75.9 14.8 17.5 96.0 2.3 6.9 TMEM200B TTMB ENSG00000253304 "Transmembrane protein 200B" Q69YZ2 1 29119429-29123903 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 60.6" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 8.8;Fibroblasts: 6.1;Leydig cells: 12.8;Melanocytes: 8.8;Peritubular cells: 15.1;Sertoli cells: 6.6;Smooth muscle cells: 9.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 28.2;BJ hTERT+ SV40 Large T+: 26.7;BJ hTERT+ SV40 Large T+ RasG12V: 29.5;fHDF/TERT166: 29.0;HBF TERT88: 25.3" "Low region specificity" "Detected in all" HPA055254 Uncertain NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA055254: AB_2682760" "unprognostic (2.55e-1)" "unprognostic (2.12e-2)" "unprognostic (8.25e-3)" "unprognostic (1.39e-1)" "unprognostic (4.71e-3)" "unprognostic (6.84e-2)" "unprognostic (1.91e-1)" "unprognostic (1.52e-2)" "unprognostic (6.25e-2)" "unprognostic (1.33e-1)" "unprognostic (6.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.24e-2)" "unprognostic (1.81e-2)" "unprognostic (2.70e-1)" "unprognostic (1.12e-1)" "unprognostic (7.16e-3)" 16.8 4.4 2.0 4.0 6.3 0.0 11.8 6.9 3.3 47.2 6.6 29.5 2.3 60.6 7.8 5.6 21.5 7.3 7.0 1.9 2.4 9.4 8.4 10.5 1.2 2.2 2.1 33.3 2.5 26.1 3.6 6.5 2.2 24.6 4.1 0.3 4.1 39.7 2.2 5.8 9.2 35.1 2.0 6.4 6.4 13.3 2.6 1.0 5.0 2.6 1.3 20.9 24.3 2.1 21.0 0.0 3.4 0.0 28.2 23.4 1.1 14.4 22.6 26.7 29.5 1.1 2.3 0.0 3.5 29.0 9.8 0.4 2.3 0.0 25.3 0.1 0.9 0.1 5.7 1.8 19.6 0.0 0.1 12.5 2.7 20.1 3.9 1.1 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.3 1.9 0.0 5.8 0.0 0.0 0.0 0.3 0.1 0.0 1.7 20.7 0.0 0.1 9.5 0.0 0.0 0.0 9.4 0.4 19.9 0.4 0.0 0.0 0.0 11.6 0.0 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 6.3 6.9 3.3 1.9 2.4 2.2 2.1 2.2 2.0 2.6 2.1 2.0 3.2 0.6 0.7 0.2 1.9 0.4 0.2 2.8 0.8 0.6 1.8 1.0 1.5 0.7 0.0 2.1 0.1 0.2 0.1 0.0 0.0 0.1 1.0 8.8 1.3 0.0 0.0 0.3 0.0 0.5 6.1 0.0 0.6 0.0 0.0 1.1 1.2 0.1 0.0 0.1 0.0 0.0 0.0 1.2 2.4 12.8 0.1 8.8 1.9 0.1 0.1 0.0 0.0 0.1 0.0 0.1 15.1 0.0 0.3 0.0 5.9 0.4 1.9 6.6 1.1 9.5 0.3 0.6 0.2 0.6 0.5 0.4 0.0 0.0 0.3 TNN TNW ENSG00000120332 "Tenascin N" Q9UQP3 1 175067833-175148075 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 12.0;breast: 4.9" "Cell type enhanced" "Detected in some" "Adipocytes: 6.1;Fibroblasts: 7.5;Hepatic stellate cells: 2.5;Langerhans cells: 2.5;Smooth muscle cells: 10.4" "Cancer enhanced" "Detected in some" "breast cancer: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 5.6;NB-4: 3.6;THP-1: 11.1;U-266/70: 2.7;U-937: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB010907, HPA026726, HPA026764" Uncertain "Secreted to extracellular matrix" NA NA 34000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "CAB010907: AB_477565, HPA026726: AB_10601771, HPA026764: AB_10601859" "unprognostic (1.16e-3)" "unprognostic (2.23e-2)" "unprognostic (1.35e-1)" "unprognostic (2.21e-2)" "unprognostic (1.34e-1)" "unprognostic (1.48e-1)" "unprognostic (1.48e-1)" "unprognostic (3.55e-1)" "unprognostic (5.25e-3)" "unprognostic (1.01e-2)" "unprognostic (4.69e-1)" "unprognostic (5.07e-1)" "unprognostic (1.08e-3)" "unprognostic (1.76e-2)" "unprognostic (9.38e-3)" "unprognostic (1.89e-2)" "unprognostic (1.02e-2)" 12.0 0.2 0.0 0.1 0.1 0.0 4.9 0.0 0.1 0.1 0.1 0.3 0.8 0.0 0.0 0.1 0.0 1.7 0.3 0.2 0.0 0.4 1.3 0.4 0.1 0.0 0.1 0.0 0.3 0.8 2.0 0.1 0.0 0.0 0.1 0.0 3.2 0.0 0.0 3.1 0.4 0.4 0.1 0.4 0.4 0.1 0.1 0.1 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 11.1 0.0 0.0 0.0 0.0 0.0 2.7 0.4 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.1 6.1 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.7 0.0 0.1 7.5 0.0 0.1 0.0 0.0 2.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 2.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 10.4 0.4 1.4 0.0 1.8 0.1 0.1 0.0 0.0 0.1 TRPC1 HTRP-1 ENSG00000144935 "Transient receptor potential cation channel subfamily C member 1" P48995 3 142724034-142807888 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Astrocytes: 93.7;Excitatory neurons: 144.6;Granulosa cells: 91.8;Inhibitory neurons: 184.4;Microglial cells: 49.6;Oligodendrocyte precursor cells: 154.8;Oligodendrocytes: 164.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 23.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009387, HPA021130" Supported Approved Vesicles NA NA "Cluster 21: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Vesicles "CAB009387: AB_2240941, HPA021130: AB_1858361" "unprognostic (1.66e-1)" "unprognostic (7.38e-2)" "unprognostic (1.56e-2)" "unprognostic (4.37e-5)" "unprognostic (5.53e-1)" "unprognostic (1.40e-2)" "unprognostic (5.90e-3)" "unprognostic (1.59e-2)" "unprognostic (1.36e-1)" "unprognostic (2.17e-1)" "unprognostic (8.46e-3)" "unprognostic (6.25e-2)" "prognostic unfavorable (2.72e-5)" "unprognostic (1.44e-3)" "unprognostic (1.57e-1)" "unprognostic (1.61e-1)" "unprognostic (2.49e-2)" 5.2 4.7 7.3 1.9 7.9 0.3 4.7 10.9 7.5 9.1 5.8 7.6 1.2 11.1 5.2 3.6 8.6 5.4 10.1 7.9 7.0 3.2 0.8 3.3 1.9 7.1 5.6 14.2 1.4 6.5 10.3 3.5 7.7 7.0 2.5 22.8 2.9 7.8 1.2 3.6 3.9 10.6 6.1 2.8 3.2 4.8 6.1 1.5 5.1 3.6 1.0 6.3 6.9 7.9 4.2 5.7 10.8 1.2 9.7 23.9 4.8 6.8 10.5 8.4 12.2 1.7 1.1 0.0 2.1 7.0 14.2 0.3 3.0 3.2 12.2 1.0 4.1 6.8 2.6 2.9 4.0 0.4 0.0 11.4 3.2 7.9 9.4 14.2 4.9 0.0 0.2 0.0 12.1 2.6 0.4 0.5 6.0 0.1 3.1 0.0 5.0 0.0 5.9 0.1 6.7 4.8 8.1 0.0 1.5 9.9 3.3 0.1 4.3 10.1 1.6 14.0 9.1 3.9 1.8 2.1 7.7 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 7.3 7.9 10.9 7.5 7.9 7.0 7.1 5.6 7.7 6.1 6.1 7.9 6.2 3.2 0.5 93.7 2.9 2.9 1.6 1.2 7.4 17.9 0.9 1.8 12.0 1.5 0.6 5.5 16.7 0.2 0.3 0.0 0.0 0.3 3.6 0.5 10.8 4.6 1.8 0.4 144.6 0.2 0.2 13.2 0.0 0.9 0.0 91.8 3.6 0.0 0.1 13.5 184.4 0.0 0.0 0.0 1.6 2.9 8.4 0.5 1.8 49.6 0.1 7.7 0.0 154.8 164.8 0.1 0.0 10.9 1.5 0.9 0.0 0.7 3.0 16.0 0.0 10.4 12.0 9.8 2.8 0.7 1.1 0.3 2.2 1.7 0.0 0.3 ZDHHC15 "DHHC15, FLJ31812, MRX91" ENSG00000102383 "Zinc finger DHHC-type palmitoyltransferase 15" Q96MV8 X 75368427-75523502 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Acyltransferase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.2;Inhibitory neurons: 17.7;Oligodendrocyte precursor cells: 17.1" "Cancer enhanced" "Detected in some" "glioma: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 3.2;K-562: 2.1;LHCN-M2: 2.2;MOLT-4: 2.4;NTERA-2: 2.0;RH-30: 3.1;RPTEC TERT1: 1.7;SH-SY5Y: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003618, HPA064901" Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" Cytosol "HPA003618: AB_2217686, HPA064901: " "unprognostic (8.28e-2)" "unprognostic (1.73e-1)" "unprognostic (8.05e-2)" "unprognostic (1.62e-5)" "unprognostic (1.64e-2)" "unprognostic (1.00e-1)" "unprognostic (4.00e-4)" "unprognostic (1.96e-2)" "unprognostic (3.19e-1)" "unprognostic (8.70e-2)" "unprognostic (3.77e-3)" "unprognostic (1.40e-1)" "unprognostic (4.78e-13)" "unprognostic (2.60e-3)" "unprognostic (1.17e-2)" "unprognostic (1.09e-1)" "unprognostic (9.67e-4)" 0.8 1.5 1.7 0.3 1.7 0.1 1.6 1.8 1.5 1.6 1.3 1.0 0.2 1.9 1.0 0.8 1.2 0.8 1.7 1.5 2.5 1.5 0.2 1.2 0.3 2.2 2.2 2.5 1.1 1.1 1.1 0.0 2.0 1.1 0.5 1.9 4.5 1.1 0.3 0.7 0.3 1.5 1.8 0.8 0.4 0.6 3.0 0.8 2.0 0.5 0.2 0.7 0.8 2.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 2.1 0.0 2.2 0.0 2.4 0.0 2.0 0.0 0.0 0.0 3.1 0.0 1.7 0.0 0.8 2.6 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.5 0.0 0.4 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.7 1.8 1.5 1.5 2.5 2.2 2.2 2.0 1.8 3.0 2.0 2.9 6.4 3.1 8.5 0.1 4.0 1.6 0.0 3.4 4.2 2.0 1.5 9.5 1.5 1.3 5.5 4.2 0.0 0.3 0.0 0.0 0.7 0.0 0.2 2.9 3.5 1.8 0.4 18.2 0.7 0.0 3.5 0.0 0.3 1.3 2.5 2.2 0.1 0.1 0.0 17.7 0.0 0.0 0.0 4.4 0.2 0.9 0.1 0.0 5.6 0.0 2.2 1.0 17.1 9.1 0.2 0.0 3.8 0.0 0.7 0.0 1.0 0.0 2.3 6.6 5.4 2.5 0.2 0.7 2.2 3.7 0.0 0.5 2.3 0.0 0.6 ZEB2 "KIAA0569, SIP-1, SIP1, ZFHX1B" ENSG00000169554 "Zinc finger E-box binding homeobox 2" O60315 2 144364364-144521057 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant, Epilepsy, Hirschsprung disease, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 363.7" "Cell type enhanced" "Detected in many" "Horizontal cells: 662.9;Inhibitory neurons: 539.3;Oligodendrocytes: 1489.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 154.0;THP-1: 181.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003456 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" Nucleoli "Nucleoplasm, Cytosol" "HPA003456: AB_10603840" "unprognostic (1.02e-1)" "unprognostic (2.08e-1)" "unprognostic (1.12e-1)" "unprognostic (2.42e-1)" "unprognostic (4.12e-1)" "unprognostic (4.17e-2)" "unprognostic (3.69e-1)" "unprognostic (3.77e-2)" "unprognostic (5.83e-2)" "unprognostic (7.90e-2)" "unprognostic (1.33e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (6.04e-5)" "unprognostic (1.11e-2)" "unprognostic (1.73e-2)" "unprognostic (7.45e-2)" "unprognostic (1.32e-2)" 61.3 45.2 185.6 56.8 258.3 127.5 29.5 138.3 165.5 52.4 3.0 24.5 21.9 29.6 9.6 27.9 20.3 43.9 45.7 132.5 155.4 18.2 23.3 41.2 43.2 238.3 214.5 70.5 5.7 6.7 3.3 62.1 222.8 18.5 29.9 35.5 9.6 22.7 20.8 12.8 25.9 33.3 183.2 69.4 18.0 16.2 249.6 10.6 13.3 18.8 24.2 46.6 24.1 363.7 1.6 2.0 83.4 0.1 98.9 49.7 0.3 35.1 35.1 38.5 37.1 0.0 0.8 6.6 0.1 37.4 10.6 0.4 14.5 0.1 47.6 37.6 11.2 154.0 6.3 0.2 23.0 26.4 113.2 42.1 0.9 48.9 22.9 33.7 29.4 0.0 43.0 4.1 45.2 0.2 0.4 79.9 12.3 0.0 1.9 44.1 63.5 0.2 0.4 0.6 0.7 22.1 4.2 0.2 97.3 27.5 0.2 181.4 45.9 42.9 0.7 87.5 11.0 47.1 0.3 7.5 66.7 78.4 122.6 27.8 47.7 12.2 21.0 42.6 1.9 9.2 2.7 10.7 27.0 9.4 1.9 7.7 15.2 7.3 43.9 21.5 0.6 19.0 185.6 258.3 138.3 165.5 132.5 155.4 238.3 214.5 222.8 183.2 249.6 363.7 32.6 6.4 19.2 121.8 92.4 24.9 1.2 0.6 3.4 158.6 2.2 4.3 71.0 1.5 10.1 5.5 4.2 1.7 426.2 0.1 1.9 0.7 2.2 2.1 84.7 29.2 0.0 127.0 228.2 0.8 2.0 123.0 13.3 2.5 157.5 99.3 79.2 4.6 144.5 662.9 539.3 0.0 0.0 435.0 276.3 7.2 120.5 435.0 103.2 343.8 233.6 69.3 223.5 381.0 1489.6 0.2 1.1 66.5 132.3 1.8 0.0 10.3 4.0 11.9 184.1 185.0 198.7 2.9 11.3 3.4 19.6 4.7 136.7 108.8 0.4 2.2 ZNF519 "FLJ36809, HsT2362" ENSG00000175322 "Zinc finger protein 519" Q8TB69 18 14057457-14132490 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Excitatory neurons: 83.3;Inhibitory neurons: 64.3;Oligodendrocyte precursor cells: 30.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HL-60: 5.5;SCLC-21H: 6.6" HPA028982 Uncertain Approved Nucleoli NA NA "Cluster 72: Non-specific - Transcription" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoli "HPA028982: AB_10610705" "unprognostic (1.85e-2)" "unprognostic (4.22e-2)" "unprognostic (2.16e-1)" "unprognostic (1.15e-3)" "unprognostic (1.90e-1)" "unprognostic (2.53e-2)" "unprognostic (6.70e-2)" "unprognostic (3.43e-1)" "unprognostic (2.31e-2)" "unprognostic (1.18e-1)" "unprognostic (6.47e-2)" "unprognostic (1.50e-2)" "unprognostic (1.16e-5)" "unprognostic (1.40e-2)" "unprognostic (1.58e-1)" "unprognostic (2.38e-1)" "unprognostic (3.65e-4)" 0.9 0.5 0.3 0.3 0.3 0.3 0.9 1.3 1.0 2.4 0.0 2.4 0.1 1.9 0.3 1.7 1.5 0.4 0.8 0.3 0.2 0.3 0.4 0.5 0.6 0.2 0.2 2.0 0.6 0.2 0.8 0.2 0.3 1.2 0.5 0.4 0.8 0.4 0.4 0.9 1.0 0.7 0.2 0.9 0.7 0.8 0.2 0.6 0.9 0.3 0.4 1.6 1.7 0.4 0.6 0.0 2.3 2.2 0.0 0.5 0.9 0.4 0.3 1.7 1.6 0.7 0.6 1.2 0.8 0.2 0.5 0.6 2.3 0.3 2.5 1.0 1.4 2.7 1.3 0.4 0.0 5.5 0.8 0.1 0.6 1.2 0.3 0.3 0.2 1.9 0.9 1.8 0.7 0.3 3.7 0.8 0.9 1.2 0.7 3.3 2.9 1.6 0.3 0.4 6.6 1.2 1.2 0.1 0.8 1.8 0.4 0.8 0.2 2.7 2.5 1.1 0.9 0.3 0.6 1.3 0.7 1.8 1.8 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.2 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.3 1.3 1.0 0.3 0.2 0.2 0.2 0.3 0.2 0.2 0.4 4.6 6.4 9.5 17.6 7.6 2.0 2.4 2.5 11.4 15.0 2.8 3.8 4.9 1.5 1.3 0.0 2.1 3.2 3.3 0.6 1.9 2.5 1.1 0.6 11.2 3.2 1.2 8.0 83.3 2.0 4.2 7.6 3.1 1.1 3.8 18.2 2.9 0.7 1.7 3.3 64.3 1.9 4.1 3.1 1.9 1.8 6.5 2.3 1.8 23.4 1.6 5.9 6.2 30.2 15.9 1.0 0.4 9.1 6.0 1.2 0.3 0.7 2.0 7.4 0.0 8.4 4.2 10.7 12.2 18.3 1.3 0.8 6.4 3.6 2.4 1.4