Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ADGRG3 "GPR97, Pb99, PGR26" ENSG00000182885 "Adhesion G protein-coupled receptor G3" Q86Y34 16 57668277-57689378 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 147.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 4.4;dendritic cells: 2.9;Endothelial cells: 2.8;Erythroid cells: 5.3;T-cells: 4.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 5 "cerebral cortex: 10.6" "Immune cell enhanced" "Detected in some" "eosinophil: 142.3;neutrophil: 169.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 169.8" "Group enriched" "Detected in some" 6 "NB-4: 5.0;SK-MEL-30: 2.1;U-937: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA040469 Uncertain NA NA 1200000 "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA040469: AB_10794032" "unprognostic (4.41e-3)" "unprognostic (3.49e-2)" "unprognostic (1.17e-1)" "unprognostic (1.14e-2)" "unprognostic (8.84e-2)" "unprognostic (1.64e-2)" "unprognostic (1.50e-4)" "unprognostic (5.25e-3)" "unprognostic (1.22e-2)" "unprognostic (2.22e-1)" "unprognostic (1.93e-1)" "unprognostic (1.53e-1)" "unprognostic (2.67e-3)" "unprognostic (4.75e-2)" "unprognostic (3.77e-1)" "unprognostic (1.00e-1)" "unprognostic (2.90e-1)" 8.5 0.3 0.1 14.6 0.2 147.0 1.7 0.1 10.6 1.1 0.3 1.6 2.2 1.0 0.0 1.0 4.3 2.3 1.2 0.1 0.1 0.8 2.3 12.0 0.3 0.2 0.2 0.4 0.7 0.0 0.2 1.7 2.0 0.6 1.4 0.0 0.4 0.1 0.3 0.7 3.4 2.6 0.1 29.4 1.3 0.3 0.4 0.6 3.2 2.8 0.4 3.8 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 75.5 0.0 142.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 169.8 36.4 0.1 0.0 0.0 0.9 0.1 0.2 0.1 10.6 0.1 0.1 0.2 0.2 2.0 0.1 0.4 0.1 1.0 9.6 4.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.6 0.0 1.8 0.0 0.0 0.3 2.9 0.0 0.0 0.1 0.6 0.5 0.2 2.8 0.0 5.3 0.1 0.0 0.1 0.9 0.0 0.4 2.5 0.2 2.2 0.0 0.1 0.0 0.1 0.0 0.0 1.0 0.0 0.6 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.9 0.0 0.0 0.2 1.5 0.0 0.0 0.2 0.2 0.0 0.7 0.1 0.0 0.1 4.2 0.0 0.0 0.1 ALOX5 5-LOX ENSG00000012779 "Arachidonate 5-lipoxygenase" P09917 10 45374176-45446119 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Leukotriene biosynthesis" "Dioxygenase, Hydrolase, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 72.8;lymphoid tissue: 93.9" "Cell type enhanced" "Detected in many" "B-cells: 63.7;granulocytes: 201.3;Hofbauer cells: 85.0;Kupffer cells: 78.5;Macrophages: 86.5;monocytes: 59.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 13.9;Daudi: 40.9;HMC-1: 24.0;U-266/70: 30.8;U-698: 11.0" "Region enriched" "Detected in single" 4 "white matter: 2.9" "Low region specificity" "Detected in all" HPA071285 Enhanced Supported Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA071285: AB_2686379" "unprognostic (2.57e-2)" "unprognostic (2.81e-1)" "unprognostic (4.82e-2)" "unprognostic (1.75e-2)" "unprognostic (7.98e-3)" "unprognostic (1.26e-1)" "unprognostic (5.32e-2)" "unprognostic (8.69e-2)" "unprognostic (1.86e-2)" "unprognostic (6.91e-2)" "unprognostic (5.04e-2)" "unprognostic (3.42e-1)" "prognostic unfavorable (1.80e-5)" "unprognostic (5.59e-3)" "unprognostic (4.22e-2)" "unprognostic (1.53e-1)" "prognostic favorable (7.18e-4)" 16.8 8.4 1.4 8.4 1.1 31.1 12.7 2.8 2.9 6.1 1.0 11.0 3.0 6.9 0.3 10.7 11.1 3.4 6.7 1.2 1.8 8.3 5.5 72.8 6.7 4.1 2.5 2.6 23.2 0.9 3.2 3.6 2.7 11.8 2.3 0.1 14.1 1.5 2.1 5.6 35.8 4.9 2.5 93.9 9.3 2.1 2.2 2.6 4.7 3.7 8.9 40.0 7.9 4.2 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 7.4 40.9 0.7 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.1 8.6 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 5.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.1 0.0 2.7 0.0 5.2 0.7 0.0 0.0 0.2 0.0 0.1 0.1 0.6 0.0 0.0 2.2 0.0 0.0 30.8 2.8 11.0 0.0 0.1 0.0 462.5 225.6 317.6 0.3 198.4 0.6 133.9 5.3 1.7 119.7 98.5 0.7 0.5 457.8 0.2 210.5 2.4 1.2 136.1 1.4 1.1 2.8 2.9 1.2 1.8 4.1 2.5 2.7 2.5 2.2 4.2 0.7 16.0 38.4 1.3 63.7 1.1 7.3 0.2 1.2 1.3 7.3 4.3 2.2 12.8 9.5 9.2 2.1 0.7 1.7 1.7 0.0 20.9 0.5 0.7 0.5 3.0 7.1 1.7 2.8 21.6 2.0 1.7 13.7 4.4 201.3 2.2 3.6 1.1 85.0 0.0 1.1 2.0 14.2 78.5 17.8 1.1 0.3 86.5 0.0 47.8 59.5 0.7 4.1 4.0 1.4 18.4 0.6 0.0 13.8 4.0 9.4 0.2 2.6 0.3 13.1 0.3 1.1 0.3 1.1 9.2 1.4 4.1 5.9 0.7 3.2 45.3 ALOX5AP FLAP ENSG00000132965 "Arachidonate 5-lipoxygenase activating protein" P20292 13 30713478-30764426 "Disease related genes, Predicted membrane proteins" "Leukotriene biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 487.2;lung: 183.3;lymphoid tissue: 138.5" "Cell type enhanced" "Detected in many" "dendritic cells: 691.3;granulocytes: 609.1;Hofbauer cells: 492.2;Langerhans cells: 335.4;Macrophages: 637.0;NK-cells: 280.2;T-cells: 368.6" "Cancer enhanced" "Detected in all" "glioma: 49.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 9703.9;eosinophil: 4033.4;neutrophil: 4968.7;plasmacytoid DC: 3555.3" "Group enriched" "Detected in all" 8 "dendritic cells: 3555.3;granulocytes: 9703.9" "Cell line enhanced" "Detected in many" "HDLM-2: 658.4;HL-60: 352.3;HMC-1: 1072.9;THP-1: 434.2;U-937: 321.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026592 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA026592: AB_10601115" "unprognostic (1.17e-2)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (4.64e-3)" "unprognostic (7.18e-2)" "unprognostic (7.10e-2)" "unprognostic (7.79e-2)" "unprognostic (1.04e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (6.44e-4)" "unprognostic (7.83e-2)" "unprognostic (6.63e-2)" "prognostic unfavorable (5.68e-4)" "unprognostic (1.33e-1)" "unprognostic (3.19e-2)" "unprognostic (2.72e-2)" "unprognostic (2.59e-1)" 51.6 36.1 10.8 100.6 11.6 487.2 25.7 12.5 18.1 18.8 13.4 22.8 21.6 17.4 7.1 21.8 24.5 40.0 12.4 10.2 15.7 13.3 19.7 183.3 77.2 21.0 15.6 10.6 14.1 9.6 6.1 37.2 21.1 13.2 21.4 3.7 19.9 15.5 3.8 7.4 28.3 42.6 16.6 138.5 20.0 4.3 17.7 93.2 9.1 24.7 108.2 65.6 11.9 31.3 0.6 0.8 1.2 0.0 0.6 0.0 0.1 0.0 0.4 0.0 0.0 1.3 7.1 156.3 2.2 0.0 5.2 1.2 0.0 4.6 0.1 658.4 0.0 18.7 0.3 1.0 0.7 352.3 1072.9 0.8 0.2 0.1 37.9 8.1 1.4 33.3 0.1 3.2 1.9 0.1 19.8 12.7 0.0 0.0 0.2 3.2 3.9 12.4 1.4 0.3 10.2 0.1 0.2 0.3 0.9 2.3 0.0 434.2 1.1 0.0 3.2 0.3 2.6 66.2 0.5 103.8 1.0 321.1 1.4 9703.9 322.4 4033.4 546.0 17.2 808.3 477.9 536.4 449.0 198.5 489.2 271.6 260.7 4968.7 98.0 12.4 3555.3 843.9 775.2 10.8 11.6 12.5 18.1 10.2 15.7 21.0 15.6 21.1 16.6 17.7 31.3 3.5 41.7 102.0 0.0 117.6 23.7 2.6 1.8 1.2 0.0 3.3 9.1 4.1 10.0 23.7 0.0 0.0 3.1 691.3 4.0 15.6 2.3 5.6 14.3 0.7 17.2 26.4 27.1 0.4 1.0 4.0 11.2 21.4 0.7 609.1 1.9 7.1 1.8 492.2 0.0 0.4 2.0 4.1 144.3 335.4 4.5 4.7 637.0 42.7 13.1 217.1 0.1 280.2 0.5 0.3 6.4 3.1 4.1 31.1 1.5 7.3 2.0 11.1 0.1 32.9 4.4 4.0 0.4 1.1 1.7 24.7 4.9 368.6 0.0 2.0 1.4 APOBEC3A "ARP3, PHRBN" ENSG00000128383 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3A" P31941 22 38952741-38992778 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 93.9;lymphoid tissue: 48.3;urinary bladder: 24.4" "Cell type enriched" "Detected in many" 4 "Urothelial cells: 426.0" "Group enriched" "Detected in many" 4 "cervical cancer: 11.3;head and neck cancer: 15.8" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 1014.5" "Lineage enriched" "Detected in many" 8 "monocytes: 1014.5" "Not detected" "Not detected" "HPA043237, HPA056980, HPA066719" Approved Uncertain Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "HPA043237: AB_10795980, HPA056980: AB_2683298, HPA066719: AB_2685711" "unprognostic (6.45e-3)" "unprognostic (1.44e-2)" "unprognostic (1.12e-1)" "unprognostic (5.21e-3)" "unprognostic (1.31e-1)" "unprognostic (2.72e-2)" "unprognostic (1.91e-1)" "unprognostic (1.91e-1)" "unprognostic (3.52e-1)" "unprognostic (2.59e-3)" "unprognostic (9.01e-3)" "unprognostic (2.00e-1)" "unprognostic (1.13e-2)" "unprognostic (1.76e-1)" "unprognostic (4.98e-2)" "unprognostic (3.41e-1)" "unprognostic (1.91e-1)" 7.9 0.4 0.5 20.9 0.5 93.9 0.8 0.7 1.1 2.2 0.8 1.5 1.4 0.4 0.3 12.2 4.2 6.3 1.4 0.9 0.5 0.7 2.0 13.4 1.1 0.6 0.4 0.2 1.5 0.4 0.3 3.5 0.7 0.4 0.6 0.2 6.7 0.3 0.5 0.6 0.8 1.7 0.3 48.3 1.1 0.2 0.5 2.4 1.0 3.7 21.1 24.4 10.3 1.0 0.1 0.0 0.1 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.5 0.1 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.4 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.3 0.6 0.3 34.7 223.9 8.4 0.7 1014.5 1.5 3.1 0.6 0.7 10.4 0.8 0.7 0.7 121.7 0.9 298.5 1.3 1.0 149.1 0.5 0.5 0.7 1.1 0.9 0.5 0.6 0.4 0.7 0.3 0.5 1.0 0.7 28.9 33.6 0.0 0.5 1.3 16.0 1.8 0.0 0.6 0.7 0.3 0.1 0.0 24.1 1.8 4.2 0.3 0.2 17.5 0.0 0.1 0.6 0.5 0.2 1.4 0.0 8.0 0.0 0.2 0.3 6.3 0.0 0.6 25.9 0.3 0.7 0.4 14.9 0.0 0.0 0.0 2.0 18.8 41.4 0.1 0.3 91.3 16.0 0.0 17.9 0.8 2.1 0.0 0.0 1.3 27.4 0.4 15.6 6.7 4.5 0.2 10.7 0.8 0.0 1.0 1.2 0.1 0.4 48.7 6.8 0.3 3.1 0.2 1.7 426.0 CD177 "HNA2A, NB1, PRV1" ENSG00000204936 "CD177 molecule" 19 43353686-43363172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 285.9;intestine: 164.6" "Group enriched" "Detected in some" 5 "Distal enterocytes: 632.4;Paneth cells: 314.8" "Cancer enhanced" "Detected in many" "prostate cancer: 27.6" "Group enriched" "Detected in many" 4 "cerebellum: 3.6;cerebral cortex: 7.7;pons: 2.3" "Immune cell enriched" "Detected in some" 7 "neutrophil: 8.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 8.7" "Cell line enriched" "Detected in some" 26 "RPMI-8226: 98.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041820, HPA046601, HPA077640" Enhanced "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA041820: AB_2677691, HPA046601: AB_2679716, HPA077640: " "unprognostic (4.32e-2)" "prognostic favorable (3.66e-4)" "unprognostic (1.04e-2)" "unprognostic (2.04e-3)" "unprognostic (1.61e-1)" "unprognostic (3.89e-2)" "unprognostic (7.10e-2)" "unprognostic (2.94e-1)" "unprognostic (2.05e-1)" "unprognostic (1.45e-1)" "unprognostic (8.38e-2)" "unprognostic (1.90e-2)" "unprognostic (2.45e-1)" "unprognostic (2.70e-1)" "unprognostic (1.16e-1)" "unprognostic (5.01e-2)" "unprognostic (1.24e-1)" 4.8 0.4 0.1 7.2 0.3 285.9 1.3 3.6 7.7 6.0 3.7 155.2 0.3 0.4 0.2 2.2 2.3 0.2 2.2 0.3 0.1 1.9 2.6 20.6 0.2 0.3 1.0 0.3 1.1 0.0 2.9 1.6 2.3 64.8 164.6 0.1 1.8 0.2 0.7 0.4 0.7 3.0 0.3 64.4 1.4 0.2 0.4 1.4 0.7 0.8 10.4 2.1 5.4 0.5 2.1 0.0 0.0 0.0 0.0 0.0 0.3 1.0 1.3 0.6 0.6 0.0 0.0 0.1 2.4 0.6 1.7 0.2 0.1 0.0 1.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 1.2 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.4 1.2 0.0 0.2 0.0 0.0 98.0 1.4 0.3 0.7 0.0 0.5 0.1 0.0 0.2 0.0 0.0 0.0 1.0 0.3 2.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 1.2 0.0 0.7 0.0 0.1 0.3 3.6 7.7 0.3 0.1 0.3 1.0 2.3 0.3 0.4 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 3.1 0.0 0.0 0.0 0.0 632.4 0.0 0.5 0.4 0.2 0.1 0.0 8.4 3.6 0.0 0.2 0.0 0.2 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.2 87.2 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 314.8 0.0 0.1 29.2 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 28.0 0.2 CDKN2D "INK4D, p19" ENSG00000129355 "Cyclin dependent kinase inhibitor 2D" P55273 19 10566460-10569059 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 283.7" "Cell type enhanced" "Detected in all" "dendritic cells: 146.8;Erythroid cells: 116.6;Macrophages: 105.4;NK-cells: 155.5;Spermatocytes: 126.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 90.6;MOLT-4: 113.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011201, HPA043546" Enhanced Supported Nucleoplasm,Cytosol NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm Cytosol "CAB011201: AB_261049, HPA043546: AB_2678545" "unprognostic (3.08e-1)" "prognostic favorable (1.02e-4)" "unprognostic (3.57e-2)" "unprognostic (1.49e-2)" "unprognostic (3.29e-2)" "unprognostic (1.37e-2)" "prognostic unfavorable (4.82e-4)" "unprognostic (2.08e-1)" "unprognostic (1.08e-2)" "unprognostic (6.55e-2)" "unprognostic (3.28e-1)" "unprognostic (1.50e-1)" "unprognostic (3.27e-3)" "unprognostic (9.90e-2)" "unprognostic (4.52e-1)" "unprognostic (4.43e-2)" "unprognostic (1.40e-1)" 13.7 9.8 61.0 13.3 64.9 283.7 9.5 43.9 86.9 9.4 37.3 14.2 6.3 7.0 3.1 14.3 11.0 6.4 18.8 64.8 59.7 11.3 7.1 30.8 23.9 53.8 51.5 7.1 5.8 3.3 15.7 8.2 59.9 8.0 5.6 16.3 7.3 4.1 19.7 18.1 14.5 7.8 46.1 42.4 9.4 38.6 57.6 78.0 6.2 15.9 16.1 11.2 12.9 57.4 30.8 4.8 15.1 10.0 8.0 12.2 3.8 19.8 23.2 21.4 18.8 6.1 7.3 8.5 6.4 21.1 21.6 6.4 5.2 5.1 7.7 34.3 12.6 90.6 5.8 10.2 9.2 9.2 70.2 5.1 16.2 11.0 8.2 17.7 6.1 52.6 3.8 72.3 21.5 4.3 113.9 48.3 3.0 23.4 22.7 18.4 14.7 5.1 9.7 2.6 21.3 11.2 14.0 10.4 15.2 2.8 9.4 24.0 4.7 25.2 12.9 42.1 30.1 44.9 16.5 15.8 26.7 15.5 18.4 143.5 17.7 79.7 30.2 23.2 24.2 56.7 24.9 34.1 17.4 50.0 23.3 27.4 139.9 41.1 35.6 51.0 22.5 31.8 61.0 64.9 43.9 86.9 64.8 59.7 53.8 51.5 59.9 46.1 57.6 57.4 35.2 6.4 7.0 4.6 65.2 23.2 13.7 17.1 38.7 32.4 11.1 15.2 9.2 5.7 8.2 5.5 12.5 4.8 146.8 11.8 9.8 7.7 21.2 26.9 10.2 29.3 7.2 116.6 18.5 4.9 8.4 11.0 3.6 16.7 21.0 4.8 26.7 3.8 10.4 47.1 14.8 6.4 36.7 42.2 47.7 13.7 7.2 105.4 30.2 1.9 46.4 22.2 155.5 1.0 8.2 14.2 9.4 6.0 9.2 11.4 5.0 5.1 10.9 37.1 19.7 8.3 25.8 126.0 83.7 38.6 33.1 4.9 63.4 4.5 6.9 23.8 CEACAM4 CGM7 ENSG00000105352 "CEA cell adhesion molecule 4" O75871 19 41618971-41627074 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 21.3;lymphoid tissue: 32.6" "Cell type enhanced" "Detected in some" "Kupffer cells: 41.1;Macrophages: 20.9;monocytes: 9.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "neutrophil: 122.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 122.7" "Cell line enriched" "Detected in single" 6 "U-937: 4.1" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (1.10e-2)" "unprognostic (1.52e-2)" "unprognostic (1.24e-1)" "unprognostic (4.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.83e-2)" "unprognostic (9.11e-2)" "unprognostic (5.59e-2)" "unprognostic (1.79e-2)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (2.17e-1)" "unprognostic (2.09e-9)" "unprognostic (3.65e-2)" "unprognostic (2.95e-2)" "unprognostic (1.47e-1)" "unprognostic (4.34e-1)" 2.1 0.5 0.1 4.8 0.1 21.3 0.5 0.1 0.2 0.4 0.2 0.7 0.3 0.3 0.8 1.0 1.0 1.0 0.8 0.1 0.1 0.8 1.0 5.7 0.9 0.2 0.2 0.2 1.2 0.0 0.3 0.3 0.2 1.1 0.2 0.0 0.8 0.0 0.2 0.3 1.8 1.0 0.1 32.6 0.8 0.1 0.2 0.3 0.4 0.6 0.6 0.7 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 30.1 5.6 0.0 23.1 0.1 0.7 1.2 0.0 23.3 0.0 0.7 0.0 122.7 0.0 9.9 0.2 11.3 12.1 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.2 0.1 0.2 0.2 0.1 0.0 3.9 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 3.1 0.0 0.0 0.0 0.0 41.1 1.6 0.2 0.0 20.9 1.8 1.9 9.2 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 CLEC4D "CD368, CLECSF8, Dectin-3, MCL, Mpcl" ENSG00000166527 "C-type lectin domain family 4 member D" Q8WXI8 12 8509475-8522366 "CD markers, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "bone marrow: 64.7" "Group enriched" "Detected in some" 5 "Kupffer cells: 10.6;Macrophages: 11.9;monocytes: 15.1" "Cancer enriched" "Detected in single" 50 "testis cancer: 11.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "classical monocyte: 57.1;neutrophil: 98.7" "Group enriched" "Detected in many" 32 "granulocytes: 98.7;monocytes: 57.1" "Group enriched" "Detected in some" 5 "NB-4: 2.4;NTERA-2: 9.0;SuSa: 9.1;U-937: 5.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA004906 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 5: NTERA-2 - Transcription" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA004906: AB_1078535" "unprognostic (1.10e-1)" "unprognostic (4.94e-2)" "unprognostic (4.78e-2)" "unprognostic (1.27e-1)" "unprognostic (4.39e-1)" "unprognostic (3.84e-2)" "unprognostic (7.61e-2)" "unprognostic (1.16e-1)" "unprognostic (1.90e-1)" "unprognostic (2.21e-1)" "unprognostic (2.70e-1)" "unprognostic (3.81e-1)" "unprognostic (7.91e-5)" "unprognostic (1.12e-2)" "unprognostic (8.57e-2)" "unprognostic (7.89e-2)" "unprognostic (2.18e-1)" 2.3 0.2 0.0 7.3 0.1 64.7 0.2 0.0 0.2 3.1 0.3 0.1 0.1 0.1 0.5 0.4 0.7 0.4 0.3 0.0 0.0 0.2 0.5 3.1 0.6 0.1 0.1 0.0 0.5 0.0 0.0 0.7 0.1 0.1 0.1 0.6 0.4 0.0 0.1 0.0 0.2 0.8 0.0 7.0 0.2 0.2 0.4 0.3 0.1 0.7 0.3 2.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 9.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.9 57.1 0.0 0.0 4.5 0.0 0.3 0.0 0.1 2.4 0.0 0.0 0.1 98.7 0.0 1.2 0.7 0.0 12.4 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.4 0.1 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 10.6 0.8 0.0 0.0 11.9 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 CLEC4E "CLECSF9, mincle" ENSG00000166523 "C-type lectin domain family 4 member E" Q9ULY5 12 8533305-8540905 "Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 75.7;lymphoid tissue: 52.3" "Cell type enhanced" "Detected in some" "Glandular and luminal cells: 31.9;Kupffer cells: 158.0;Macrophages: 115.2;monocytes: 109.5" "Cancer enhanced" "Detected in many" "testis cancer: 6.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 16 "classical monocyte: 128.8;neutrophil: 448.8" "Group enriched" "Detected in many" 17 "granulocytes: 448.8;monocytes: 128.8" "Group enriched" "Detected in some" 4 "NB-4: 4.3;RPTEC TERT1: 12.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA004935 Uncertain Uncertain Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 41: Macrophages - Immune response" Cytosol "HPA004935: AB_2667299" "unprognostic (3.05e-2)" "unprognostic (2.01e-2)" "unprognostic (8.91e-2)" "unprognostic (3.76e-1)" "unprognostic (1.76e-1)" "unprognostic (9.71e-3)" "unprognostic (1.77e-1)" "unprognostic (1.24e-1)" "unprognostic (9.29e-2)" "unprognostic (1.83e-1)" "unprognostic (1.16e-1)" "unprognostic (2.11e-2)" "unprognostic (7.65e-3)" "unprognostic (1.62e-1)" "unprognostic (1.51e-1)" "unprognostic (8.44e-2)" "unprognostic (2.29e-1)" 13.3 5.4 2.3 37.5 2.1 75.7 4.5 1.8 4.4 5.8 2.2 2.2 0.4 2.3 0.4 3.2 5.5 11.8 2.5 2.3 2.9 3.6 6.6 22.4 7.6 1.3 1.3 1.7 6.2 1.7 1.9 2.1 1.2 2.3 1.0 1.3 1.4 1.2 0.7 0.9 3.1 5.7 0.7 52.3 2.5 1.1 2.0 2.2 10.5 5.0 2.3 9.6 1.7 2.9 0.1 0.4 0.4 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.1 1.5 0.1 0.1 2.0 0.0 0.1 0.1 0.2 0.2 0.1 0.3 0.2 0.2 0.1 0.5 0.1 0.0 1.5 0.0 0.5 0.2 0.2 0.2 0.2 0.0 0.1 0.0 4.3 0.3 0.0 0.0 0.0 0.2 0.1 12.4 0.1 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.4 1.0 0.5 0.1 1.0 0.1 0.2 0.1 0.1 1.3 0.4 0.1 0.2 128.8 0.5 0.1 18.1 0.3 0.1 0.1 0.1 16.9 0.1 0.0 0.1 448.8 0.0 0.7 0.7 0.0 30.3 2.3 2.1 1.8 4.4 2.3 2.9 1.3 1.3 1.2 0.7 2.0 2.9 6.2 0.0 4.7 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 5.7 1.8 1.8 0.0 0.0 0.3 0.0 0.0 9.0 0.3 2.1 4.4 3.5 0.0 0.0 0.0 0.0 0.1 1.4 0.0 31.9 0.0 0.0 7.1 2.1 5.6 0.0 0.0 0.0 0.0 158.0 9.0 2.9 0.9 115.2 0.0 0.0 109.5 0.0 4.1 0.0 0.0 0.4 0.0 0.4 1.3 0.0 0.0 0.2 0.7 0.0 13.1 0.2 0.4 0.2 0.5 0.1 0.0 0.1 1.1 0.0 0.0 0.1 CSF3R "CD114, GCSFR" ENSG00000119535 "Colony stimulating factor 3 receptor" Q99062 1 36466043-36483278 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 379.7;lung: 136.7;lymphoid tissue: 375.6;placenta: 105.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 230.8;Cytotrophoblasts: 423.8;Kupffer cells: 177.7;monocytes: 197.6;Syncytiotrophoblasts: 1194.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 1962.3" "Lineage enriched" "Detected in many" 7 "granulocytes: 1962.3" "Group enriched" "Detected in some" 18 "BEWO: 70.8;NB-4: 20.3;THP-1: 50.3;U-937: 47.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB017116, HPA048086" Enhanced "Intracellular and membrane" NA NA 150000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB017116: , HPA048086: AB_2680257" "unprognostic (5.57e-3)" "unprognostic (8.05e-2)" "unprognostic (7.23e-2)" "unprognostic (3.87e-2)" "unprognostic (2.88e-1)" "unprognostic (2.92e-2)" "unprognostic (2.86e-2)" "unprognostic (1.35e-1)" "unprognostic (1.83e-1)" "unprognostic (5.65e-2)" "unprognostic (2.47e-1)" "unprognostic (3.44e-1)" "prognostic unfavorable (5.72e-4)" "unprognostic (6.33e-2)" "prognostic unfavorable (3.79e-4)" "unprognostic (2.03e-1)" "unprognostic (2.31e-2)" 36.2 7.1 5.8 148.2 5.6 379.7 13.0 6.7 19.0 5.2 6.3 6.4 2.6 3.1 0.4 5.6 31.5 15.8 14.6 5.5 7.3 9.7 22.9 136.7 7.3 10.3 7.8 3.2 4.9 1.6 5.5 105.1 11.4 7.5 1.8 0.1 7.4 1.8 3.6 1.6 9.8 12.2 9.6 375.6 9.9 1.2 10.7 5.7 5.8 21.7 2.7 22.2 6.2 11.9 0.0 0.0 0.0 0.0 0.0 0.0 70.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 1.6 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 20.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 1.5 0.0 50.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 47.8 0.0 1.1 280.8 8.7 0.2 56.8 0.6 0.1 0.4 0.2 97.2 0.4 0.1 0.3 1962.3 3.4 24.1 3.3 0.6 158.4 5.8 5.6 6.7 19.0 5.5 7.3 10.3 7.8 11.4 9.6 10.7 11.9 0.7 25.6 230.8 0.0 3.3 1.0 0.5 0.0 0.0 0.0 5.9 4.7 1.8 0.0 10.0 0.0 0.0 423.8 2.9 0.0 0.0 0.0 0.4 0.3 6.4 4.8 0.0 4.6 0.2 0.0 47.3 8.0 1.5 0.2 18.9 1.1 3.9 1.2 64.1 0.0 0.2 0.0 0.0 177.7 39.2 0.7 0.3 111.5 0.0 77.8 197.6 0.2 6.2 0.5 0.3 0.1 0.0 0.0 0.7 0.3 0.0 0.5 6.6 0.2 0.0 0.3 1.0 0.0 0.4 0.2 0.1 1194.8 4.0 0.0 0.0 3.0 CXCR1 "CD181, CDw128a, CKR-1, CMKAR1, IL8RA" ENSG00000163464 "C-X-C motif chemokine receptor 1" P25024 2 218162841-218166962 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 5.1;dendritic cells: 5.2;granulocytes: 2.5;NK-cells: 11.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 14 "neutrophil: 1472.7" "Lineage enriched" "Detected in many" 62 "granulocytes: 1472.7" "Cell line enriched" "Detected in single" 26 "HMC-1: 5.8" "Not detected" "Not detected" HPA031991 Uncertain NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA031991: AB_2674103" "unprognostic (2.80e-1)" "unprognostic (2.91e-2)" "unprognostic (3.53e-2)" "unprognostic (5.74e-2)" "unprognostic (1.19e-1)" "unprognostic (1.68e-1)" "unprognostic (2.14e-2)" "unprognostic (3.36e-2)" "unprognostic (2.32e-1)" "unprognostic (1.57e-1)" "unprognostic (8.27e-2)" "unprognostic (2.15e-2)" "unprognostic (2.88e-1)" "unprognostic (5.47e-2)" "unprognostic (2.97e-1)" "unprognostic (1.30e-1)" "unprognostic (8.85e-2)" 13.2 0.5 0.3 25.1 0.5 9.5 0.4 0.3 1.7 0.7 0.5 0.4 0.2 0.2 0.0 1.6 2.9 4.1 1.8 0.3 0.3 0.5 2.0 9.7 0.3 0.4 0.4 0.1 1.5 0.3 0.2 2.6 1.2 0.3 0.2 0.0 0.5 0.1 0.4 0.3 0.6 1.8 0.3 40.5 0.9 0.2 0.5 1.8 0.4 12.0 0.6 5.6 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.2 2.3 2.9 23.7 0.8 0.3 0.2 2.1 6.1 0.7 0.1 0.4 8.7 1472.7 1.5 3.2 0.9 0.3 8.3 0.3 0.5 0.3 1.7 0.3 0.3 0.4 0.4 1.2 0.3 0.5 0.3 0.0 0.0 5.1 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 2.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.7 0.0 0.0 0.2 0.0 11.3 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 FCAR CD89 ENSG00000186431 "Fc fragment of IgA receptor" P24071 19 54874235-54891420 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "IgA-binding protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 26.1;lung: 10.5;lymphoid tissue: 13.5" "Group enriched" "Detected in some" 6 "Kupffer cells: 12.8;Macrophages: 18.0" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "classical monocyte: 1.2;neutrophil: 4.0" "Group enriched" "Detected in many" 27 "granulocytes: 4.0;monocytes: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA014050 Approved Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "HPA014050: AB_1846338" "unprognostic (1.46e-1)" "unprognostic (5.74e-2)" "unprognostic (1.30e-1)" "unprognostic (4.71e-3)" "unprognostic (3.46e-1)" "unprognostic (2.02e-1)" "unprognostic (7.99e-2)" "unprognostic (1.54e-2)" "unprognostic (1.59e-2)" "unprognostic (4.70e-2)" "unprognostic (1.41e-2)" "unprognostic (7.05e-2)" "unprognostic (4.19e-6)" "unprognostic (9.23e-2)" "unprognostic (8.10e-3)" "unprognostic (8.04e-3)" "unprognostic (9.81e-2)" 4.5 0.3 0.0 1.0 0.0 26.1 0.7 0.0 0.3 0.2 0.0 0.6 0.0 0.2 0.0 0.3 3.4 0.0 1.5 0.0 0.0 0.5 1.7 10.5 0.0 0.1 0.0 0.3 0.2 0.0 0.3 0.0 0.1 0.3 0.0 0.0 0.4 0.0 0.4 0.1 0.4 0.1 0.0 13.5 0.8 0.1 0.0 0.0 0.5 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.3 0.1 0.3 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 12.8 0.3 0.0 0.0 18.0 0.0 1.0 2.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.7 0.5 0.0 0.3 0.3 0.1 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.1 FCGR2A "CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, IGFR2" ENSG00000143226 "Fc fragment of IgG receptor IIa" P12318 1 161505430-161524013 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 101.7;placenta: 107.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 178.2;Kupffer cells: 159.1;Langerhans cells: 336.6;Macrophages: 305.0;monocytes: 97.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 2322.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 2322.4" "Cell line enhanced" "Detected in some" "HEL: 29.4;HMC-1: 56.2;K-562: 17.9;NB-4: 15.8;THP-1: 61.9;U-937: 26.7" "HPA010718, HPA010776, HPA014730" Enhanced Supported "Golgi apparatus,Plasma membrane" NA NA 46000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Golgi apparatus" "HPA010718: AB_1078463, HPA010776: , HPA014730: AB_2669074" "unprognostic (2.57e-2)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (4.12e-2)" "unprognostic (5.89e-2)" "unprognostic (6.17e-2)" "unprognostic (1.24e-2)" "unprognostic (1.17e-1)" "unprognostic (7.63e-2)" "unprognostic (1.17e-3)" "unprognostic (2.43e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (6.49e-7)" "unprognostic (8.85e-3)" "unprognostic (6.47e-3)" "unprognostic (1.54e-1)" "unprognostic (3.42e-2)" 68.0 24.8 7.3 101.7 6.6 48.6 13.3 8.0 12.1 18.1 13.9 16.0 8.1 7.3 4.3 11.7 14.6 36.8 11.5 6.5 11.5 12.7 12.3 77.5 16.1 15.1 11.4 7.2 12.7 8.5 7.6 107.3 13.3 6.1 21.0 2.3 9.9 9.6 2.6 3.5 10.8 40.9 11.9 61.8 10.1 4.4 13.8 9.8 6.4 10.2 7.7 68.3 5.2 21.8 0.0 0.0 0.0 2.4 0.0 0.3 0.0 0.0 0.5 0.0 0.1 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 29.4 0.3 0.0 0.7 8.6 56.2 0.5 0.0 0.0 0.0 0.7 0.1 0.0 17.9 0.5 0.0 0.0 0.4 15.8 0.0 0.0 1.1 0.2 1.2 8.1 0.0 0.0 0.1 0.0 0.0 0.0 4.6 0.0 0.0 61.9 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.7 0.4 26.7 6.6 2.4 358.3 421.8 0.7 268.4 1.0 3.2 0.5 0.4 89.9 1.7 0.4 0.7 2322.4 0.4 232.7 3.8 0.9 170.3 7.3 6.6 8.0 12.1 6.5 11.5 15.1 11.4 13.3 11.9 13.8 21.8 2.3 22.4 49.1 0.0 8.6 8.7 0.9 0.3 1.2 0.4 1.1 3.8 1.8 2.8 12.1 0.0 0.0 1.0 3.4 0.1 9.8 0.2 38.2 0.1 0.8 15.6 0.0 3.0 0.1 0.6 1.6 8.9 1.1 0.1 30.4 0.1 3.9 2.1 178.2 0.0 0.1 0.0 0.0 159.1 336.6 66.5 1.5 305.0 17.8 12.2 97.3 0.5 7.2 1.0 0.6 0.5 0.0 0.0 4.6 0.3 0.0 9.6 3.7 0.2 6.6 1.5 6.0 0.4 0.6 0.8 7.7 1.6 4.8 0.2 0.1 0.4 FFAR2 "FFA2R, GPR43" ENSG00000126262 "Free fatty acid receptor 2" O15552 19 35443907-35451767 "G-protein coupled receptors, Predicted membrane proteins" "Immunity, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.3;lymphoid tissue: 22.2" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 24.1;Intestinal goblet cells: 8.9;Kupffer cells: 11.9;Macrophages: 15.4;Prostatic glandular cells: 7.7" "Cancer enhanced" "Detected in many" "prostate cancer: 6.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 25 "eosinophil: 85.0;neutrophil: 249.7" "Lineage enriched" "Detected in many" 38 "granulocytes: 249.7" "Cell line enhanced" "Detected in some" "HMC-1: 3.9;OE19: 1.8;SK-BR-3: 1.1;THP-1: 1.2;U-937: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA023985 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA023985: AB_1849302" "unprognostic (7.75e-3)" "unprognostic (5.65e-2)" "unprognostic (4.33e-3)" "unprognostic (1.68e-1)" "unprognostic (2.18e-1)" "unprognostic (2.55e-2)" "unprognostic (6.16e-2)" "unprognostic (2.04e-1)" "unprognostic (1.92e-2)" "unprognostic (9.04e-2)" "unprognostic (2.30e-2)" "unprognostic (4.60e-2)" "unprognostic (5.17e-4)" "unprognostic (1.48e-1)" "unprognostic (4.76e-2)" "unprognostic (9.42e-2)" "unprognostic (1.03e-2)" 4.9 0.3 0.2 17.8 0.4 20.3 2.3 0.2 0.4 0.2 0.6 0.8 3.3 0.1 0.0 1.3 1.0 1.4 1.0 0.2 0.2 0.3 1.5 7.5 0.1 0.4 0.4 0.0 0.6 0.3 0.1 1.6 0.5 1.1 0.7 0.1 0.7 0.0 0.2 1.1 4.6 1.3 0.2 22.2 1.2 0.0 0.4 0.7 0.4 3.7 0.7 6.0 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.6 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 1.1 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 3.1 2.1 85.0 0.0 5.6 0.0 0.1 0.0 0.0 0.9 0.2 0.0 0.0 249.7 0.0 6.5 0.1 0.0 0.7 0.2 0.4 0.2 0.4 0.2 0.2 0.4 0.4 0.5 0.2 0.4 0.8 5.6 0.0 3.2 0.0 0.6 0.1 0.4 0.3 0.0 0.0 0.2 0.3 0.4 0.0 2.7 0.0 0.0 0.0 0.3 0.3 0.0 0.3 0.2 0.0 0.1 0.8 24.1 0.0 0.0 0.0 0.1 1.4 0.0 0.0 5.1 0.0 0.4 0.0 5.0 0.0 0.0 8.9 2.0 11.9 2.6 0.1 0.0 15.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 7.7 1.1 0.0 2.2 0.0 0.0 0.4 2.4 0.1 0.2 0.0 0.6 0.1 1.3 0.1 0.6 1.5 FGR "c-fgr, p55c-fgr, SRC2" ENSG00000000938 "FGR proto-oncogene, Src family tyrosine kinase" P09769 1 27612064-27635185 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 207.8;lung: 86.5;lymphoid tissue: 141.1" "Cell type enhanced" "Detected in many" "Kupffer cells: 182.2;Langerhans cells: 63.8;Macrophages: 155.9;monocytes: 159.7;NK-cells: 259.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Daudi: 86.0;U-266/70: 153.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002024 Enhanced Approved "Plasma membrane,Aggresome" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Aggresome "HPA002024: AB_1078503" "unprognostic (2.66e-2)" "unprognostic (1.51e-2)" "unprognostic (6.32e-2)" "unprognostic (9.74e-3)" "unprognostic (6.66e-3)" "unprognostic (6.71e-2)" "unprognostic (5.77e-2)" "unprognostic (1.25e-1)" "unprognostic (1.81e-2)" "unprognostic (7.45e-2)" "unprognostic (2.79e-2)" "unprognostic (1.10e-1)" "unprognostic (1.94e-2)" "unprognostic (6.26e-2)" "unprognostic (3.93e-2)" "unprognostic (2.30e-1)" "unprognostic (8.12e-3)" 25.0 6.8 12.8 62.2 11.9 207.8 16.0 11.9 19.1 7.6 11.5 6.0 3.9 8.1 1.7 5.2 15.6 12.7 8.7 11.4 12.3 7.5 10.8 86.5 27.5 13.6 12.7 2.9 5.8 1.6 2.7 7.9 14.5 7.2 4.0 0.7 6.6 2.4 3.2 4.5 10.1 16.3 12.5 141.1 5.9 2.5 17.2 8.4 7.4 6.5 20.0 17.8 7.3 12.6 0.0 0.0 0.3 0.0 0.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 86.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.0 0.0 1.7 29.3 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.3 0.0 0.0 3.8 5.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 153.1 2.1 6.5 0.0 19.5 0.0 30.8 381.4 229.4 189.5 469.1 11.3 54.0 15.8 89.1 196.1 84.0 8.0 78.4 272.9 264.5 405.2 9.0 1.2 494.1 12.8 11.9 11.9 19.1 11.4 12.3 13.6 12.7 14.5 12.5 17.2 12.6 8.6 6.4 20.0 0.0 24.9 2.8 0.6 0.2 0.0 0.0 0.4 0.6 1.6 1.5 5.7 1.8 0.0 0.5 55.2 0.0 0.0 0.0 0.3 0.1 0.2 14.9 0.0 7.4 0.2 0.2 0.7 2.7 1.5 0.1 13.3 0.1 6.8 1.9 56.8 0.0 0.1 0.0 0.0 182.2 63.8 0.7 0.3 155.9 1.8 6.5 159.7 0.1 259.5 1.0 0.4 0.0 1.2 0.0 4.2 0.4 0.0 0.7 1.5 0.0 0.0 0.7 0.6 0.2 0.5 0.5 1.1 1.0 28.0 0.0 0.0 2.5 FPR1 "FMLP, FPR" ENSG00000171051 "Formyl peptide receptor 1" P21462 19 51745172-51804110 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 195.3;lymphoid tissue: 166.0" "Group enriched" "Detected in many" 5 "Hofbauer cells: 119.6;Kupffer cells: 215.3;Macrophages: 178.5;monocytes: 89.7" "Cancer enhanced" "Detected in all" "glioma: 23.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 4199.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 4199.5" "Group enriched" "Detected in some" 5 "LHCN-M2: 17.2;U-87 MG: 67.1" "Not detected" "Not detected" "HPA046550, HPA061744" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA046550: AB_2679694, HPA061744: AB_2684600" "unprognostic (5.54e-2)" "unprognostic (4.16e-2)" "unprognostic (1.88e-1)" "unprognostic (1.22e-1)" "unprognostic (8.50e-2)" "unprognostic (1.38e-1)" "unprognostic (1.96e-1)" "unprognostic (1.14e-1)" "unprognostic (1.15e-1)" "unprognostic (5.48e-3)" "unprognostic (4.59e-2)" "unprognostic (8.34e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.03e-2)" "unprognostic (4.52e-3)" "unprognostic (1.54e-2)" "unprognostic (1.70e-3)" 69.6 10.0 3.8 166.0 4.4 195.3 5.3 4.1 8.7 8.2 5.7 4.6 3.1 3.7 0.5 8.9 15.4 28.6 7.5 3.6 8.1 4.5 21.4 50.8 12.7 15.2 8.2 2.4 11.2 5.1 3.5 45.1 11.9 3.1 3.3 2.6 4.1 2.3 1.8 1.3 5.2 42.9 8.6 129.2 5.4 2.2 9.9 8.4 3.1 22.8 10.3 66.9 2.7 18.2 0.5 0.8 0.3 0.4 1.0 2.1 0.5 0.2 0.0 0.5 2.0 0.3 0.7 1.2 0.6 0.0 3.9 0.4 0.0 0.0 0.1 0.1 0.0 0.7 0.9 1.0 6.0 0.3 0.5 4.8 0.2 1.8 1.8 9.2 0.0 0.3 0.1 0.6 17.2 0.9 0.1 0.3 0.4 0.3 0.7 0.3 0.7 0.0 1.5 0.5 0.2 0.3 0.6 0.1 0.5 0.2 1.0 1.1 1.0 2.0 0.4 0.1 3.5 0.2 0.0 0.5 67.1 1.7 0.1 317.1 759.9 204.9 1.6 319.7 1.5 0.7 1.0 0.7 174.1 1.0 1.0 1.2 4199.5 0.4 201.8 8.1 1.3 420.3 3.8 4.4 4.1 8.7 3.6 8.1 15.2 8.2 11.9 8.6 9.9 18.2 0.1 16.0 25.7 0.0 1.8 0.6 0.3 0.0 0.0 1.0 0.1 0.3 0.2 0.0 15.5 0.0 0.0 1.1 0.3 0.0 0.0 0.0 1.8 0.0 0.1 6.3 0.0 2.5 0.2 0.0 1.6 4.7 0.5 0.1 26.5 0.0 2.5 2.1 119.6 0.0 0.1 0.0 0.0 215.3 4.7 2.0 0.3 178.5 0.0 3.7 89.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.4 8.8 0.3 6.6 0.6 0.8 0.6 0.8 0.2 0.0 3.0 2.5 0.0 0.0 0.1 FPR2 "ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH2, FPRL1, HM63, LXA4R" ENSG00000171049 "Formyl peptide receptor 2" P25090 19 51752026-51770531 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 56.1" "Cell type enhanced" "Detected in some" "Early spermatids: 9.0;Hofbauer cells: 12.7;Kupffer cells: 18.8;Late spermatids: 26.8;Macrophages: 61.3;monocytes: 23.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 10 "neutrophil: 1187.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 1187.9" "Cell line enriched" "Detected in some" 20 "U-937: 32.7" "Not detected" "Not detected" HPA029154 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA029154: AB_10602133" "unprognostic (3.11e-1)" "unprognostic (5.20e-2)" "unprognostic (1.71e-2)" "unprognostic (1.44e-1)" "unprognostic (1.07e-1)" "unprognostic (1.65e-1)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (1.00e-1)" "unprognostic (1.23e-1)" "unprognostic (5.04e-2)" "unprognostic (3.90e-4)" "unprognostic (3.41e-5)" "unprognostic (1.08e-2)" "unprognostic (4.69e-2)" "unprognostic (5.10e-2)" "unprognostic (1.90e-1)" 13.6 1.2 0.3 56.1 0.6 16.6 0.6 0.3 2.6 0.5 0.9 0.8 1.0 0.5 0.1 1.8 1.8 5.9 0.9 0.3 0.3 0.4 4.9 9.4 1.9 0.6 0.5 1.5 2.3 0.3 0.2 7.6 0.9 0.4 0.5 0.1 0.5 0.3 0.3 0.4 1.3 6.7 0.3 17.2 0.7 2.4 1.2 1.6 0.7 4.2 0.8 15.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.8 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.9 32.7 0.0 3.6 122.0 5.8 0.2 122.7 0.7 0.1 0.2 0.2 16.6 0.2 0.1 0.2 1187.9 0.2 85.0 3.3 0.1 46.0 0.3 0.6 0.3 2.6 0.3 0.3 0.6 0.5 0.9 0.3 1.2 0.5 0.0 0.0 5.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 9.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.0 5.1 0.0 0.4 0.4 12.7 0.0 0.0 0.0 0.0 18.8 0.8 26.8 0.0 61.3 0.0 0.0 23.3 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.4 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 GCA GCL ENSG00000115271 Grancalcin P28676 2 162318840-162371595 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 325.7" "Cell type enhanced" "Detected in all" "Early spermatids: 185.0;Kupffer cells: 183.3;Macrophages: 153.5;monocytes: 228.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 327.4;neutrophil: 864.2" "Lineage enriched" "Detected in all" 7 "granulocytes: 864.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035033, HPA035034" Enhanced Supported "Plasma membrane,Cytosol" NA NA 1300000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "Plasma membrane" "HPA035033: AB_10669854, HPA035034: AB_10669900" "unprognostic (9.62e-2)" "unprognostic (9.76e-2)" "unprognostic (3.33e-1)" "unprognostic (3.82e-2)" "unprognostic (2.60e-1)" "unprognostic (1.06e-1)" "unprognostic (2.33e-3)" "unprognostic (1.36e-1)" "unprognostic (8.87e-2)" "unprognostic (2.49e-2)" "unprognostic (1.20e-1)" "unprognostic (9.78e-2)" "unprognostic (6.56e-2)" "unprognostic (5.80e-2)" "unprognostic (3.07e-1)" "unprognostic (3.06e-2)" "unprognostic (1.32e-2)" 30.5 13.5 16.4 62.6 23.0 325.7 17.6 20.2 28.8 12.2 11.4 18.0 19.3 9.8 24.6 10.9 16.2 23.0 9.7 15.9 17.7 18.3 15.0 26.5 33.0 25.5 20.7 8.5 16.6 10.4 8.2 25.2 23.6 12.2 19.6 10.6 12.3 9.7 2.7 7.0 18.7 18.8 21.6 70.1 25.1 24.1 19.5 18.4 17.0 14.9 25.4 26.1 5.7 37.3 2.6 4.2 10.7 0.0 2.5 2.2 0.4 4.0 11.1 6.2 11.1 8.7 30.6 3.7 27.0 0.3 14.2 1.6 4.1 12.7 7.7 17.1 16.8 33.5 2.9 17.7 3.0 41.6 9.1 2.8 4.3 5.7 1.2 15.8 0.9 25.9 0.6 12.1 0.5 33.0 0.9 24.2 6.5 22.5 16.4 14.2 2.7 18.5 32.7 18.6 6.9 12.0 5.1 23.3 19.7 12.5 15.8 17.7 0.8 1.6 11.2 17.8 6.2 11.5 23.2 0.6 9.2 15.8 7.7 38.8 132.4 327.4 2.7 78.4 3.5 21.6 4.8 4.8 63.2 21.1 8.1 5.0 864.2 2.5 63.3 17.2 10.2 71.4 16.4 23.0 20.2 28.8 15.9 17.7 25.5 20.7 23.6 21.6 19.5 37.3 28.8 16.0 36.5 10.1 54.5 15.4 28.2 19.6 12.5 10.2 32.6 16.4 4.1 50.1 21.2 33.1 2.1 55.5 17.3 14.4 76.3 49.5 185.0 21.1 9.1 26.4 39.4 36.1 25.9 60.5 20.8 14.4 43.8 24.9 44.9 13.6 48.9 15.0 107.9 11.8 15.4 29.9 32.6 183.3 60.5 32.8 10.8 153.5 16.0 17.8 228.5 21.1 10.3 1.0 98.0 36.5 25.7 6.4 23.4 24.3 18.4 69.7 24.7 4.4 6.6 12.2 18.3 52.6 13.5 15.1 18.2 46.9 16.3 16.7 28.9 21.0 HRH2 ENSG00000113749 "Histamine receptor H2" P25021 5 175658030-175710756 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.0;heart muscle: 26.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 26.2;Excitatory neurons: 62.2;Inhibitory neurons: 19.1;Kupffer cells: 29.4;Macrophages: 36.2;monocytes: 24.3;Smooth muscle cells: 33.6" "Group enriched" "Detected in many" 5 "melanoma: 2.9;renal cancer: 4.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 134.4;neutrophil: 161.7" "Group enriched" "Detected in many" 5 "granulocytes: 161.7;monocytes: 51.6" "Group enriched" "Detected in some" 4 "RPMI-8226: 65.6;SK-MEL-30: 19.2;THP-1: 18.0;U-937: 21.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA013770 Approved NA NA "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA013770: AB_1851086" "unprognostic (8.56e-3)" "unprognostic (1.62e-1)" "unprognostic (6.66e-2)" "unprognostic (5.96e-2)" "unprognostic (3.49e-2)" "unprognostic (1.80e-1)" "unprognostic (1.20e-1)" "unprognostic (4.77e-2)" "unprognostic (9.93e-2)" "unprognostic (5.76e-2)" "unprognostic (1.52e-1)" "unprognostic (2.35e-1)" "unprognostic (3.71e-3)" "unprognostic (2.01e-2)" "unprognostic (1.97e-2)" "unprognostic (1.97e-3)" "unprognostic (1.77e-2)" 7.6 1.5 4.5 12.0 14.4 37.0 3.0 1.1 9.6 5.1 0.5 1.4 6.2 2.2 0.9 1.4 2.9 2.5 26.3 5.3 1.4 2.3 1.0 7.2 3.8 1.2 1.6 1.1 1.5 1.3 0.8 10.2 1.1 4.7 1.1 0.3 1.4 4.6 0.8 2.2 6.4 3.6 1.7 18.0 19.5 0.5 3.9 8.5 1.5 1.5 3.1 4.1 2.0 5.1 0.0 1.5 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.1 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.0 0.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 5.0 2.9 0.0 0.0 7.1 0.0 65.6 0.0 0.3 0.5 0.0 0.0 0.0 19.2 1.7 0.1 18.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 21.6 4.3 134.4 45.8 52.8 0.2 44.9 0.3 0.0 3.8 1.0 23.5 0.1 7.9 4.8 161.7 2.1 51.6 18.3 3.3 15.3 4.5 14.4 1.1 9.6 5.3 1.4 1.2 1.6 1.1 1.7 3.9 5.1 1.1 0.0 2.5 1.0 1.0 0.8 0.1 0.0 0.6 9.3 3.7 0.9 26.2 0.0 2.5 0.0 0.0 0.1 8.4 0.0 0.0 0.0 0.6 0.1 0.8 1.9 0.0 3.0 62.2 2.4 0.2 3.3 7.1 0.1 2.5 3.0 0.0 0.2 11.8 1.7 19.1 0.6 0.0 29.4 8.5 1.0 0.0 36.2 0.0 10.3 24.3 0.1 0.0 1.5 1.7 0.3 0.0 0.4 0.3 0.2 0.6 0.3 0.7 0.2 0.0 0.1 33.6 0.2 0.9 0.1 0.3 0.0 4.7 0.1 0.5 0.0 IL18R1 "CD218a, IL-1Rrp, IL1RRP" ENSG00000115604 "Interleukin 18 receptor 1" Q13478 2 102311529-102398777 "CD markers, Enzymes, Plasma proteins, Predicted membrane proteins" "Inflammatory response" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 24.2;lymphoid tissue: 18.5" "Cell type enhanced" "Detected in many" "dendritic cells: 44.7;granulocytes: 111.2;Langerhans cells: 25.4;NK-cells: 42.2;T-cells: 25.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 45.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 27.4;HHSteC: 35.4;U-937: 52.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA007615 Approved Approved Mitochondria Yes No "Cluster 48: NK-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "HPA007615: AB_1851675" "unprognostic (3.60e-3)" "unprognostic (9.75e-3)" "unprognostic (1.12e-3)" "unprognostic (3.01e-2)" "unprognostic (2.34e-3)" "unprognostic (7.11e-2)" "unprognostic (2.95e-2)" "unprognostic (1.74e-2)" "unprognostic (3.59e-1)" "unprognostic (7.86e-2)" "unprognostic (3.40e-2)" "unprognostic (1.70e-1)" "prognostic unfavorable (4.52e-4)" "unprognostic (2.62e-1)" "unprognostic (1.62e-2)" "unprognostic (5.71e-2)" "unprognostic (2.48e-2)" 8.2 2.3 1.3 5.6 1.4 2.4 5.4 1.2 1.9 4.5 1.6 4.0 4.1 3.1 1.6 2.2 3.7 2.9 4.5 1.0 2.4 4.4 6.6 24.2 4.1 1.5 1.3 1.1 1.3 3.2 1.7 6.9 1.8 3.3 1.0 0.2 2.2 5.7 0.9 2.6 8.8 0.7 1.3 18.5 4.3 0.5 2.0 2.0 2.1 1.1 2.2 4.0 2.8 1.3 1.8 0.6 0.0 0.0 1.3 0.8 2.3 0.0 1.1 0.1 0.5 0.0 0.8 0.0 0.1 0.0 3.4 0.9 0.0 2.4 0.0 27.4 1.2 2.1 0.5 0.1 35.4 8.8 10.1 7.8 1.9 3.1 5.4 0.0 7.4 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.1 1.4 1.1 0.0 0.0 0.0 0.3 0.9 0.0 0.0 1.2 0.1 0.3 0.1 0.0 0.0 0.8 0.9 0.5 3.2 0.6 0.0 0.0 0.0 0.1 52.0 3.6 10.0 0.0 4.8 6.2 0.1 16.3 0.1 3.6 4.7 3.6 0.2 0.6 1.4 6.7 45.6 0.0 10.4 4.1 1.9 1.3 1.4 1.2 1.9 1.0 2.4 1.5 1.3 1.8 1.3 2.0 1.3 10.2 0.0 8.5 0.3 2.7 0.8 1.1 1.1 0.6 0.0 0.3 0.3 3.9 0.0 2.3 1.8 0.0 0.0 44.7 0.3 1.9 0.9 0.1 1.0 4.1 7.4 0.0 3.6 0.2 0.6 1.0 3.1 5.1 1.1 111.2 0.0 10.0 7.6 0.1 0.0 1.0 0.1 0.0 2.4 25.4 0.1 0.3 16.5 3.6 12.2 1.0 0.2 42.2 1.5 0.0 1.1 0.4 0.0 10.3 1.0 0.1 0.9 3.8 0.2 6.6 0.9 1.4 0.4 1.3 0.3 1.0 0.0 25.4 0.1 0.4 0.9 ITGAX CD11C ENSG00000140678 "Integrin subunit alpha X" P20702 16 31355134-31382999 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 48.1;brain: 33.7;lung: 58.1;lymphoid tissue: 67.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 51.1;granulocytes: 74.0;Hofbauer cells: 45.1;Kupffer cells: 51.5;Langerhans cells: 77.3;Macrophages: 141.7;Microglial cells: 56.2;NK-cells: 68.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 87.5" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 6 "HMC-1: 106.1" "Not detected" "Not detected" "CAB004458, HPA004723, CAB072871" Enhanced NA NA 50000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "CAB004458: AB_626859, CAB072871: AB_2665723, HPA004723: AB_1846231" "unprognostic (9.75e-3)" "unprognostic (2.49e-2)" "unprognostic (1.75e-1)" "unprognostic (1.99e-2)" "unprognostic (1.89e-1)" "unprognostic (2.29e-2)" "unprognostic (1.27e-1)" "unprognostic (9.59e-2)" "unprognostic (8.06e-3)" "unprognostic (3.20e-1)" "unprognostic (7.75e-2)" "unprognostic (3.34e-1)" "prognostic unfavorable (1.37e-4)" "unprognostic (3.92e-2)" "unprognostic (3.04e-2)" "unprognostic (2.82e-1)" "unprognostic (2.95e-2)" 12.9 2.3 6.0 42.7 8.1 48.1 4.3 8.8 33.7 2.2 8.4 2.9 2.3 2.8 0.8 2.0 5.9 10.8 3.5 6.2 9.3 2.9 6.3 58.1 23.2 14.6 11.8 1.0 2.9 1.4 2.9 4.6 14.3 3.2 4.3 0.6 4.5 1.5 1.3 2.1 5.5 4.7 13.0 67.5 4.8 0.6 18.4 4.0 2.8 3.2 12.3 9.2 2.1 24.8 0.1 0.6 0.1 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.4 0.0 9.0 0.0 0.3 0.1 0.0 0.3 0.1 18.6 0.1 0.1 0.3 0.4 0.0 1.1 106.1 0.1 0.1 1.7 0.2 0.7 1.0 0.0 0.1 0.4 0.0 0.0 0.1 8.8 0.4 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 2.7 0.1 0.0 3.3 0.8 0.0 1.6 0.0 0.1 0.1 0.0 0.2 4.9 1.8 0.3 12.8 29.1 27.1 4.8 50.3 0.4 2.1 0.1 0.7 34.7 1.0 0.1 0.7 87.5 41.4 61.0 0.6 0.1 11.5 6.0 8.1 8.8 33.7 6.2 9.3 14.6 11.8 14.3 13.0 18.4 24.8 0.8 12.8 51.1 0.0 9.8 2.8 0.3 0.0 0.0 0.1 0.6 1.3 1.5 0.0 10.5 0.0 0.0 0.4 33.6 0.0 0.0 0.3 0.0 0.4 0.5 4.8 0.0 3.4 0.2 0.0 0.6 4.4 0.0 0.5 74.0 0.0 1.1 0.1 45.1 0.0 0.3 0.0 0.0 51.5 77.3 0.0 0.0 141.7 1.8 56.2 35.3 0.1 68.0 0.5 0.3 0.2 0.0 0.0 5.5 0.2 0.0 0.3 1.5 0.1 0.0 0.6 1.0 0.0 0.2 0.0 1.1 0.4 16.5 0.1 0.0 0.1 LILRA5 "CD85, CD85f, ILT11, LILRB7, LIR9" ENSG00000187116 "Leukocyte immunoglobulin like receptor A5" A6NI73 19 54307070-54313166 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.5;lymphoid tissue: 76.3" "Group enriched" "Detected in some" 5 "Kupffer cells: 64.1;Macrophages: 136.1;monocytes: 53.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "classical monocyte: 128.6;intermediate monocyte: 252.7;neutrophil: 137.2;non-classical monocyte: 311.7" "Group enriched" "Detected in many" 6 "granulocytes: 137.2;monocytes: 311.7" "Cell line enriched" "Detected in single" 31 "RPMI-8226: 4.1" "Secreted to blood" NA NA 670000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (8.52e-2)" "unprognostic (3.61e-1)" "unprognostic (2.23e-1)" "unprognostic (1.77e-1)" "unprognostic (1.57e-2)" "unprognostic (6.56e-2)" "unprognostic (2.90e-1)" "unprognostic (1.86e-1)" "unprognostic (3.11e-1)" "unprognostic (6.61e-3)" "unprognostic (2.01e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (7.78e-4)" "unprognostic (3.61e-2)" "unprognostic (6.51e-3)" "unprognostic (4.68e-2)" "unprognostic (6.21e-2)" 7.9 1.3 0.2 36.9 0.2 43.5 1.9 0.2 0.9 0.7 0.6 1.8 0.0 1.0 0.0 0.9 4.1 1.7 2.5 0.3 0.2 1.8 3.8 22.2 0.5 0.6 0.3 0.6 0.9 0.0 0.9 1.6 0.5 1.4 1.2 0.0 1.2 0.0 0.7 0.3 2.8 6.9 0.3 76.3 2.1 0.3 0.4 0.4 1.0 0.0 0.4 15.7 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 128.6 0.5 0.0 252.7 0.3 0.0 0.0 0.0 39.2 0.1 0.0 0.0 137.2 0.3 311.7 20.3 0.1 65.0 0.2 0.2 0.2 0.9 0.3 0.2 0.6 0.3 0.5 0.3 0.4 0.4 0.1 0.0 8.5 0.0 1.3 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.5 0.0 3.1 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.4 0.1 0.0 0.1 1.0 0.0 0.0 11.4 0.0 0.4 0.7 6.5 0.0 0.1 0.0 0.0 64.1 14.3 0.0 0.0 136.1 0.0 0.0 53.4 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.4 2.2 0.0 0.0 0.8 0.2 0.1 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.1 LILRB3 "CD85a, HL9, ILT5, LIR-3, LIR3, PIR-B, PIRB" ENSG00000204577 "Leukocyte immunoglobulin like receptor B3" O75022 19 54216278-54223506 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 27.0;lymphoid tissue: 49.9" "Group enriched" "Detected in many" 5 "Hofbauer cells: 63.4;Kupffer cells: 88.6;Macrophages: 88.8;monocytes: 71.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 44.8" "Group enriched" "Detected in many" 4 "granulocytes: 44.8;monocytes: 15.4" "Not detected" "Not detected" HPA026985 Approved "Plasma membrane,Cytosol" NA NA 16000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "HPA026985: " "unprognostic (7.51e-2)" "unprognostic (3.52e-2)" "unprognostic (9.59e-2)" "unprognostic (4.53e-1)" "unprognostic (1.83e-3)" "unprognostic (5.28e-3)" "unprognostic (2.91e-2)" "unprognostic (2.55e-1)" "unprognostic (5.58e-2)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.63e-1)" "unprognostic (1.92e-8)" "unprognostic (2.18e-1)" "unprognostic (2.19e-3)" "unprognostic (1.84e-1)" "unprognostic (1.75e-1)" 9.9 3.4 0.4 8.3 0.4 14.6 2.9 0.4 2.1 1.2 0.9 2.7 0.3 1.2 0.3 1.3 5.4 0.1 3.4 0.4 0.4 2.3 4.1 27.0 0.3 1.2 0.8 1.0 1.9 0.0 1.3 1.2 1.3 1.7 0.0 0.2 2.4 0.0 1.1 0.8 2.6 0.1 0.6 49.9 2.3 0.5 1.8 0.6 1.6 0.0 0.2 3.2 1.6 1.4 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 15.4 0.6 0.1 14.3 0.2 0.1 0.3 0.0 7.2 0.1 0.0 0.1 44.8 0.0 5.6 0.5 0.0 11.6 0.4 0.4 0.4 2.1 0.4 0.4 1.2 0.8 1.3 0.6 1.8 1.4 1.5 9.6 13.0 0.3 2.2 2.4 1.2 6.5 0.0 0.7 1.6 2.2 0.4 4.3 8.3 1.8 0.0 1.5 2.1 0.6 0.0 0.3 1.3 0.8 1.9 3.0 0.0 0.8 0.2 0.6 6.7 2.9 0.0 2.2 7.6 0.5 1.8 3.2 63.4 0.0 0.1 1.9 0.0 88.6 8.4 4.1 0.3 88.8 1.8 1.9 71.2 0.9 3.1 0.0 0.1 0.2 1.3 0.7 2.1 1.6 0.4 0.4 5.2 2.9 6.6 4.3 1.3 0.8 1.5 0.1 3.0 1.2 3.8 2.6 2.0 0.4 MAP3K8 "c-COT, COT, EST, ESTF, MEKK8, Tpl-2" ENSG00000107968 "Mitogen-activated protein kinase kinase kinase 8" P41279 10 30434021-30461833 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 332.1" "Cell type enhanced" "Detected in many" "Macrophages: 225.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 44.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB005120, HPA017962" Supported Supported Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 41: Macrophages - Immune response" Cytosol "CAB005120: AB_2140669, HPA017962: AB_1853776" "unprognostic (1.91e-2)" "unprognostic (2.94e-1)" "unprognostic (3.07e-1)" "unprognostic (9.29e-2)" "unprognostic (6.73e-2)" "unprognostic (1.00e-2)" "unprognostic (1.44e-1)" "unprognostic (3.36e-2)" "unprognostic (1.41e-2)" "unprognostic (8.04e-3)" "unprognostic (8.23e-2)" "unprognostic (2.96e-1)" "prognostic unfavorable (8.76e-7)" "unprognostic (1.88e-1)" "unprognostic (1.49e-1)" "unprognostic (1.63e-2)" "unprognostic (5.98e-3)" 69.1 18.8 7.2 39.9 5.8 332.1 31.8 5.9 8.0 15.1 22.1 19.6 8.3 18.3 5.9 23.2 38.0 37.4 18.5 6.7 13.5 12.7 16.2 64.5 33.7 10.7 8.1 12.0 7.4 6.9 8.4 46.5 8.8 11.1 16.4 10.9 12.5 11.2 6.6 36.0 21.1 35.6 9.3 41.7 20.3 3.0 15.9 9.3 14.7 6.1 28.8 49.4 20.4 7.9 15.5 13.7 3.6 7.7 18.3 15.4 17.3 3.8 20.3 8.2 9.6 9.4 34.2 10.3 9.2 8.1 8.1 28.2 8.4 3.7 3.0 23.3 4.4 19.2 25.6 30.8 16.0 6.0 44.2 19.5 2.1 7.4 1.6 7.7 3.6 0.2 8.8 14.7 1.4 8.8 0.2 22.3 1.4 8.3 4.9 1.3 3.0 5.8 7.9 30.8 0.3 1.6 13.7 11.3 1.9 10.0 3.7 12.7 0.1 4.8 4.3 18.0 0.6 22.4 22.7 3.2 6.9 25.3 0.2 45.8 14.7 53.1 15.7 26.4 8.7 20.8 3.3 10.3 14.5 38.0 0.2 6.0 35.5 28.3 38.7 30.0 1.0 10.3 7.2 5.8 5.9 8.0 6.7 13.5 10.7 8.1 8.8 9.3 15.9 7.9 51.0 38.5 49.6 11.8 147.3 116.9 50.0 91.1 109.8 19.0 51.7 24.3 10.1 11.5 67.5 3.7 0.0 29.3 203.6 13.6 1.9 31.4 0.5 149.3 51.4 55.7 12.0 21.2 7.7 11.3 86.8 66.2 33.1 205.6 71.1 1.1 25.0 3.1 128.2 0.0 7.1 6.3 83.4 113.8 205.5 1.1 8.4 225.1 42.7 30.9 64.7 6.1 36.0 2.0 0.7 23.4 20.7 4.1 107.8 46.8 3.9 3.5 78.8 1.6 6.6 23.6 62.3 0.3 0.8 129.1 84.8 159.4 97.8 1.5 6.5 195.6 MCEMP1 "C19orf59, MGC132456" ENSG00000183019 "Mast cell expressed membrane protein 1" Q8IX19 19 7676628-7679826 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "bone marrow: 65.9;lung: 74.2;lymphoid tissue: 35.1" "Cell type enriched" "Detected in some" 4 "Macrophages: 147.5" "Cancer enhanced" "Detected in many" "lung cancer: 3.7" "Region enhanced" "Detected in single" "cerebral cortex: 2.1" "Group enriched" "Detected in some" 5 "classical monocyte: 102.1;neutrophil: 45.9" "Group enriched" "Detected in many" 5 "granulocytes: 45.9;monocytes: 102.1" "Group enriched" "Detected in some" 6 "THP-1: 53.7;U-937: 166.6" "Region enhanced" "Detected in single" "cerebellum: 1.3" "Not detected" "Not detected" HPA014731 Enhanced Supported "Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "HPA014731: AB_1845619" "unprognostic (4.84e-2)" "unprognostic (9.81e-4)" "unprognostic (2.41e-1)" "unprognostic (4.36e-2)" "unprognostic (8.85e-3)" "unprognostic (2.62e-3)" "unprognostic (5.57e-3)" "unprognostic (1.42e-1)" "unprognostic (2.19e-1)" "unprognostic (4.36e-2)" "unprognostic (1.77e-2)" "unprognostic (3.50e-1)" "unprognostic (2.69e-5)" "unprognostic (1.15e-2)" "unprognostic (7.37e-2)" "unprognostic (1.93e-2)" "unprognostic (7.95e-2)" 4.0 0.5 0.0 19.7 0.0 65.9 0.5 0.0 2.1 0.1 0.0 0.4 0.2 0.1 0.0 0.5 1.7 0.6 1.3 0.0 0.0 0.7 1.5 74.2 0.1 0.0 0.0 0.2 0.7 0.0 0.2 1.8 0.9 0.5 0.1 0.0 0.8 0.0 0.3 0.1 0.6 5.1 0.0 35.1 0.9 0.2 0.7 0.9 0.4 1.5 0.1 4.7 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.0 1.4 17.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 53.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 166.6 0.0 0.0 102.1 2.8 0.2 6.0 0.0 0.0 0.3 0.0 14.9 0.0 0.0 0.3 45.9 0.6 0.4 0.9 0.2 38.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.9 0.0 0.7 0.0 0.4 19.2 34.5 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.5 11.2 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.1 0.0 0.0 2.2 0.0 3.6 0.0 0.0 1.0 2.9 0.0 0.0 7.6 0.0 0.0 0.3 28.8 0.0 0.0 0.0 0.0 28.3 0.0 0.1 0.0 147.5 0.0 0.0 26.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.2 5.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.8 2.9 0.0 0.0 0.1 MEFV "FMF, MEF, TRIM20" ENSG00000103313 "MEFV innate immuity regulator, pyrin" O15553 16 3242027-3256633 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" Actin-binding "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.1;lymphoid tissue: 8.9" "Group enriched" "Detected in some" 6 "Cardiomyocytes: 7.6;Kupffer cells: 15.1;Macrophages: 15.5;monocytes: 26.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "neutrophil: 8.3" "Group enriched" "Detected in many" 4 "granulocytes: 8.3;monocytes: 5.7" "Cell line enriched" "Detected in some" 6 "THP-1: 6.6" "Not detected" "Not detected" HPA077497 Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm Cytosol "HPA077497: " "unprognostic (2.67e-1)" "unprognostic (1.06e-1)" "unprognostic (4.96e-2)" "unprognostic (2.01e-1)" "unprognostic (2.49e-2)" "unprognostic (3.10e-1)" "unprognostic (7.06e-2)" "unprognostic (3.35e-2)" "unprognostic (2.97e-2)" "unprognostic (1.09e-1)" "unprognostic (8.89e-2)" "unprognostic (3.27e-1)" "unprognostic (7.58e-7)" "unprognostic (1.08e-1)" "unprognostic (7.16e-4)" "unprognostic (1.73e-3)" "unprognostic (1.48e-1)" 2.4 0.6 0.1 6.5 0.2 6.1 0.3 0.4 1.0 0.2 0.3 0.4 0.5 0.2 0.2 0.3 0.6 1.0 0.5 0.3 0.1 0.4 0.7 4.0 0.4 0.3 0.2 0.1 0.2 0.0 0.2 0.8 0.5 0.2 0.3 0.2 0.3 0.0 0.7 0.2 0.6 1.0 0.0 8.9 0.4 1.3 0.3 0.4 0.3 0.3 0.3 1.8 0.3 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 6.6 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.2 1.1 0.0 2.4 3.2 0.1 0.0 3.4 0.0 0.1 0.1 0.0 1.7 0.2 0.0 0.1 8.3 0.3 5.7 0.1 0.0 1.2 0.1 0.2 0.4 1.0 0.3 0.1 0.3 0.2 0.5 0.0 0.3 0.4 0.2 0.0 1.3 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.3 7.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 2.5 0.0 0.4 0.2 1.0 0.0 0.1 0.0 0.0 15.1 2.4 0.3 0.0 15.5 0.0 0.0 26.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.7 0.0 0.0 0.5 0.2 0.3 0.7 0.0 0.1 0.0 0.6 0.0 0.0 0.1 MGAM MGA ENSG00000257335 Maltase-glucoamylase O43451 7 141907813-142106747 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Multifunctional enzyme" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 25.5;intestine: 87.6" "Group enriched" "Detected in some" 5 "Late spermatids: 156.4;Proximal enterocytes: 521.4" "Cancer enriched" "Detected in some" 7 "renal cancer: 4.9" "Region enhanced" "Detected in single" "cerebral cortex: 2.3" "Immune cell enriched" "Detected in some" 7 "neutrophil: 13.5" "Lineage enriched" "Detected in single" 102 "granulocytes: 13.5" "Cell line enhanced" "Detected in some" "A549: 1.8;BJ hTERT+: 1.6;HL-60: 2.8;U-937: 4.3;WM-115: 1.0" "Region enriched" "Detected in single" 12 "olfactory bulb: 2.0" "Low region specificity" "Detected in many" HPA002270 Enhanced NA NA 310000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 32: U-937 - Innate immune response" "Cluster 45: Enterocytes - Digestion" "HPA002270: AB_1079366" "unprognostic (1.02e-2)" "unprognostic (1.45e-1)" "unprognostic (1.13e-1)" "unprognostic (6.95e-3)" "unprognostic (2.80e-1)" "unprognostic (7.81e-2)" "unprognostic (7.32e-3)" "unprognostic (3.83e-2)" "unprognostic (4.97e-1)" "unprognostic (2.17e-2)" "unprognostic (6.86e-2)" "unprognostic (1.99e-1)" "prognostic favorable (6.16e-5)" "unprognostic (1.82e-1)" "unprognostic (2.82e-1)" "unprognostic (1.34e-3)" "unprognostic (3.03e-1)" 2.6 0.1 0.2 2.5 0.4 18.1 0.2 0.2 2.3 0.4 0.3 0.5 58.9 0.1 25.5 0.3 1.2 0.4 0.3 0.1 0.3 18.7 0.5 3.2 0.1 0.5 0.4 0.1 0.2 0.0 0.1 0.3 0.6 0.1 0.2 0.0 0.1 7.1 0.1 0.1 87.6 0.4 0.2 12.6 1.8 1.3 0.6 0.4 0.1 1.0 0.0 0.5 0.1 0.4 0.0 1.8 0.1 0.0 0.0 0.0 0.2 0.0 1.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.2 0.0 0.1 0.0 0.0 0.0 4.3 1.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.2 2.3 0.1 0.3 0.5 0.4 0.6 0.2 0.6 0.4 0.0 0.0 2.5 3.3 0.1 0.0 0.0 0.6 0.0 0.2 0.5 0.1 1.4 0.0 3.2 12.9 0.0 0.0 2.8 1.8 1.9 0.1 59.7 0.1 0.2 0.3 1.2 0.0 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.7 17.8 0.0 0.0 2.5 156.4 0.6 1.1 0.0 0.0 0.7 0.6 5.2 1.5 0.6 0.2 16.3 0.4 0.0 0.1 521.4 24.4 6.7 0.0 0.0 0.5 0.1 1.8 1.2 0.0 0.0 0.0 0.4 0.0 7.3 0.3 MMP25 "MMP20, MMPL1, MT6-MMP" ENSG00000008516 "Matrix metallopeptidase 25" Q9NPA2 16 3046062-3060726 "Enzymes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.1;lymphoid tissue: 81.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 6.7;Langerhans cells: 5.8;monocytes: 15.0" "Cancer enriched" "Detected in many" 5 "testis cancer: 7.1" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "basophil: 18.3;neutrophil: 20.3" "Lineage enriched" "Detected in single" 39 "granulocytes: 20.3" "Cell line enriched" "Detected in some" 15 "HMC-1: 102.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB025177, HPA055640" Uncertain Supported "Plasma membrane" "Secreted to blood" NA NA 120000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "CAB025177: , HPA055640: " "unprognostic (4.51e-3)" "unprognostic (9.28e-3)" "unprognostic (7.57e-2)" "unprognostic (2.95e-3)" "unprognostic (2.26e-1)" "prognostic favorable (1.09e-5)" "unprognostic (1.36e-1)" "unprognostic (7.39e-3)" "unprognostic (7.63e-3)" "unprognostic (2.29e-2)" "unprognostic (1.51e-1)" "unprognostic (2.53e-2)" "unprognostic (2.37e-3)" "unprognostic (1.17e-2)" "unprognostic (8.30e-2)" "unprognostic (4.01e-1)" "unprognostic (2.02e-1)" 5.8 0.4 0.5 15.1 0.4 33.1 1.4 0.3 1.6 0.7 0.6 1.7 1.1 0.5 0.1 1.3 6.2 1.1 2.4 0.3 0.3 1.4 2.9 14.4 2.6 0.6 0.5 0.4 1.2 0.2 0.8 1.0 0.6 1.0 1.4 0.0 1.2 0.1 0.5 0.7 3.5 0.9 0.3 81.8 1.9 0.4 0.7 1.4 1.2 3.5 1.9 2.2 0.9 0.3 0.0 0.0 1.2 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.7 0.1 0.0 6.7 0.5 0.0 0.0 0.0 0.0 0.2 102.2 0.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 5.7 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.2 0.3 7.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 1.1 0.1 18.3 0.2 4.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 20.3 0.5 0.0 0.4 0.2 0.0 0.5 0.4 0.3 1.6 0.3 0.3 0.6 0.5 0.6 0.3 0.7 0.3 1.0 3.2 6.7 0.0 0.7 0.4 0.4 0.2 0.0 0.8 2.0 1.3 1.0 0.0 0.8 1.8 0.0 0.0 1.8 0.2 0.0 0.4 0.0 1.2 1.2 1.0 0.0 2.7 1.6 0.6 0.2 0.6 1.1 3.8 1.3 0.2 0.0 0.3 0.1 0.0 1.9 0.2 0.0 3.5 5.8 0.0 0.0 3.3 0.0 1.0 15.0 0.3 3.1 1.5 0.5 1.3 0.0 0.7 0.8 0.4 1.2 0.2 0.1 0.0 0.0 0.7 0.9 0.1 0.2 0.6 0.3 0.0 4.0 0.1 0.3 0.3 MMP9 CLG4B ENSG00000100985 "Matrix metallopeptidase 9" P14780 20 46008908-46016561 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "bone marrow: 376.0;lymphoid tissue: 105.3" "Group enriched" "Detected in many" 5 "Hofbauer cells: 260.1;Langerhans cells: 606.0;Macrophages: 230.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebral cortex: 3.1;thalamus: 4.8" "Immune cell enriched" "Detected in some" 127 "neutrophil: 272.2" "Lineage enriched" "Detected in single" 341 "granulocytes: 272.2" "Cell line enriched" "Detected in some" 13 "NB-4: 360.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000348, HPA001238, HPA063909, CAB068199, CAB068200, CAB068201" Enhanced Approved Cytosol "Secreted to blood" NA NA 43300000 61000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB000348: , CAB068199: AB_2665675, CAB068200: AB_2665676, CAB068201: AB_2665677, HPA001238: AB_1079398, HPA063909: AB_2685150" "unprognostic (4.62e-2)" "unprognostic (1.64e-1)" "unprognostic (2.85e-2)" "prognostic favorable (2.55e-4)" "unprognostic (6.65e-3)" "unprognostic (2.82e-1)" "prognostic unfavorable (7.19e-4)" "unprognostic (1.54e-1)" "unprognostic (8.57e-2)" "unprognostic (3.21e-2)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (4.05e-5)" "unprognostic (4.65e-1)" "unprognostic (9.85e-3)" "unprognostic (2.48e-2)" "unprognostic (2.17e-3)" 19.5 0.6 0.5 61.9 0.8 376.0 8.2 0.4 3.1 2.9 0.8 5.7 11.6 1.0 0.0 2.2 2.2 3.0 3.2 0.3 0.9 2.6 3.8 21.1 103.2 0.8 0.5 0.8 1.6 0.1 1.1 2.0 0.7 1.9 3.4 0.6 3.6 0.4 0.7 3.2 12.4 1.9 0.4 105.3 11.3 1.3 4.8 17.0 2.1 0.9 36.5 12.0 1.1 0.2 0.2 0.4 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.3 0.3 28.8 0.0 0.3 0.4 0.0 1.4 0.0 0.3 0.5 0.1 0.0 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 4.0 0.0 360.6 0.8 0.0 0.2 0.4 0.3 0.1 0.0 0.0 0.6 0.6 0.0 0.6 0.0 3.7 0.3 1.2 0.3 10.3 10.9 0.1 0.3 0.3 0.2 0.2 0.1 0.8 0.2 0.0 0.7 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 272.2 0.0 0.3 0.0 0.0 0.5 0.5 0.8 0.4 3.1 0.3 0.9 0.8 0.5 0.7 0.4 4.8 0.2 0.7 0.0 5.5 0.0 3.9 34.3 0.1 61.5 0.0 3.8 0.5 2.0 0.4 1.5 0.9 0.0 8.4 1.5 2.0 0.0 0.0 0.8 0.9 0.0 0.1 7.2 0.0 0.0 0.1 1.8 2.4 2.5 0.0 0.1 1.3 0.2 0.0 0.0 260.1 3.3 0.2 0.5 0.0 1.3 606.0 0.3 0.0 230.6 56.9 0.0 2.3 1.2 0.0 0.0 0.0 1.8 0.0 0.0 0.9 0.1 0.0 0.3 6.9 5.3 0.0 0.2 45.5 6.7 11.2 0.2 28.1 1.9 3.4 0.3 0.0 0.1 NCF2 "NOXA2, p67phox" ENSG00000116701 "Neutrophil cytosolic factor 2" P19878 1 183555562-183590876 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 191.9;lung: 74.6;lymphoid tissue: 78.8" "Group enriched" "Detected in many" 5 "Ductal cells: 68.6;Hofbauer cells: 212.0;Kupffer cells: 137.9;Langerhans cells: 129.5;Macrophages: 194.4;monocytes: 223.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1313.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 26.4;HMC-1: 21.4;hTERT-HME1: 51.6;RPMI-8226: 20.0;U-2 OS: 50.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002327, HPA006040, CAB022160" Enhanced Supported Cytosol NA NA 12000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "CAB022160: , HPA002327: AB_1079550, HPA006040: AB_1854906" "unprognostic (4.97e-2)" "unprognostic (3.48e-2)" "unprognostic (2.40e-2)" "unprognostic (1.22e-3)" "unprognostic (5.83e-3)" "unprognostic (4.04e-2)" "prognostic unfavorable (7.91e-6)" "unprognostic (1.29e-1)" "unprognostic (2.45e-1)" "unprognostic (2.33e-1)" "unprognostic (5.70e-2)" "unprognostic (2.01e-1)" "unprognostic (1.57e-2)" "unprognostic (1.61e-1)" "unprognostic (1.41e-2)" "unprognostic (8.24e-2)" "unprognostic (2.36e-2)" 29.9 5.8 2.7 76.9 3.0 191.9 7.0 3.2 14.6 9.5 4.5 10.4 8.5 4.1 1.6 7.6 8.0 23.8 5.6 2.3 3.9 3.7 12.7 74.6 17.3 6.2 4.2 2.1 4.6 2.8 2.7 39.7 6.8 2.9 12.5 0.8 6.6 3.5 3.7 15.9 12.4 20.4 4.5 78.8 5.8 2.1 12.0 11.3 3.0 11.5 16.9 24.2 5.9 7.8 26.4 0.8 0.0 0.0 0.0 0.0 0.3 1.9 2.4 3.4 1.6 0.2 0.8 3.2 4.3 0.8 0.6 14.3 0.1 19.0 3.1 16.2 0.0 0.0 7.3 6.0 0.0 2.0 21.4 0.0 4.1 3.4 51.6 2.2 0.0 0.1 0.0 5.6 5.8 0.2 0.2 1.1 0.4 1.5 1.5 7.0 2.2 20.0 0.8 0.2 0.0 0.1 0.3 0.1 0.9 1.7 2.8 9.1 1.2 0.1 50.2 0.0 4.9 0.9 1.4 0.6 0.4 10.3 0.0 199.5 489.2 1313.6 1.0 348.8 1.6 14.1 4.0 1.6 246.0 10.8 2.2 1.3 799.7 2.1 326.1 13.5 11.1 298.9 2.7 3.0 3.2 14.6 2.3 3.9 6.2 4.2 6.8 4.5 12.0 7.8 0.7 9.6 15.7 0.0 8.4 5.5 0.2 13.7 1.8 0.3 0.1 0.3 1.3 7.2 17.3 0.0 0.0 1.0 9.6 0.1 3.9 68.6 1.1 1.9 0.5 3.5 0.0 1.7 0.3 3.9 1.1 2.0 0.5 1.3 7.6 0.0 3.3 1.0 212.0 0.0 0.3 0.2 26.4 137.9 129.5 2.9 0.6 194.4 7.2 3.7 223.6 0.0 6.2 0.0 0.2 27.3 2.6 0.0 3.2 0.6 0.0 0.3 32.0 0.7 13.1 0.7 6.8 0.1 0.6 0.6 4.3 1.9 3.7 0.2 0.0 1.2 NFE2 NF-E2 ENSG00000123405 "Nuclear factor, erythroid 2" Q16621 12 54292111-54301015 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 112.5;lymphoid tissue: 45.3" "Cell type enriched" "Detected in some" 5 "Erythroid cells: 265.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "basophil: 1489.2;neutrophil: 810.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 1489.2" "Group enriched" "Detected in some" 5 "HEL: 376.9;K-562: 168.1;NB-4: 118.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA001914 Enhanced Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Actin filaments" "HPA001914: AB_1079475" "unprognostic (2.68e-4)" "unprognostic (2.93e-2)" "unprognostic (2.20e-2)" "unprognostic (2.31e-2)" "unprognostic (2.33e-2)" "unprognostic (1.85e-1)" "unprognostic (1.20e-2)" "unprognostic (4.55e-2)" "unprognostic (4.12e-1)" "unprognostic (4.55e-2)" "unprognostic (3.47e-2)" "unprognostic (2.57e-3)" "unprognostic (9.90e-6)" "unprognostic (1.81e-2)" "unprognostic (8.99e-2)" "unprognostic (1.51e-2)" "unprognostic (3.46e-2)" 3.8 0.3 0.5 6.2 0.7 112.5 0.6 0.5 1.0 1.4 1.4 0.4 0.5 0.3 0.1 0.8 2.4 1.2 1.9 0.5 0.5 1.4 2.6 13.0 0.3 0.7 0.6 0.2 0.7 1.1 0.9 4.0 0.7 0.5 0.2 0.0 0.5 0.1 1.3 4.8 0.6 1.9 0.5 45.3 0.8 1.2 0.6 1.4 1.4 3.7 0.1 2.3 0.5 0.6 0.3 0.3 0.0 0.0 0.0 0.5 1.4 1.1 6.9 0.7 0.9 5.5 10.0 0.1 0.9 0.9 0.4 0.3 0.0 0.0 0.3 0.0 0.1 376.9 0.9 9.1 0.0 5.8 48.5 0.5 0.1 0.3 0.2 4.4 0.0 0.1 168.1 0.1 0.0 0.1 15.3 118.8 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 2.6 0.2 0.6 1.8 1.0 18.9 0.3 0.2 0.4 1.1 0.1 0.0 0.0 0.1 0.4 23.4 0.0 1489.2 241.7 232.3 0.6 66.7 1.0 0.3 0.8 0.5 156.7 0.5 1.0 0.7 810.6 1.1 42.0 2.7 0.2 160.2 0.5 0.7 0.5 1.0 0.5 0.5 0.7 0.6 0.7 0.5 0.6 0.6 0.0 0.0 3.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 1.5 0.1 0.0 0.0 0.2 1.3 0.0 0.0 0.1 5.9 0.1 0.0 0.0 0.0 265.6 0.0 0.0 0.5 0.4 0.0 0.1 3.8 0.1 0.4 0.2 1.0 0.0 0.0 0.0 0.0 22.8 0.2 19.0 0.0 44.3 1.8 0.0 33.9 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.8 0.0 0.0 0.1 0.0 0.3 1.3 0.0 0.3 1.2 1.1 0.0 0.1 0.1 NLRP12 "CLR19.3, Monarch1, NALP12, PAN6, PYPAF7, RNO2" ENSG00000142405 "NLR family pyrin domain containing 12" P59046 19 53793741-53824394 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;lymphoid tissue: 4.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 7.4;granulocytes: 7.6;Kupffer cells: 11.2;Macrophages: 7.8;monocytes: 20.5" "Cancer enriched" "Detected in single" 5 "testis cancer: 2.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "basophil: 56.9;classical monocyte: 18.1;eosinophil: 23.2;neutrophil: 29.8" "Group enriched" "Detected in many" 5 "granulocytes: 56.9;monocytes: 18.1" "Group enriched" "Detected in some" 4 "HMC-1: 4.6;THP-1: 4.1;U-87 MG: 4.3;U-937: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA042981 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA042981: AB_10795712" "unprognostic (6.92e-2)" "unprognostic (3.11e-1)" "unprognostic (6.66e-3)" "unprognostic (9.82e-2)" "unprognostic (1.81e-4)" "unprognostic (3.90e-2)" "unprognostic (5.79e-2)" "unprognostic (6.26e-2)" "unprognostic (1.29e-1)" "unprognostic (1.60e-5)" "unprognostic (1.63e-1)" "unprognostic (1.68e-1)" "unprognostic (3.35e-2)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (1.46e-2)" "unprognostic (4.48e-1)" 0.9 0.0 0.1 2.2 0.1 6.0 0.1 0.0 0.2 0.1 0.1 0.1 0.2 0.0 0.0 0.1 0.3 0.3 0.2 0.0 0.0 0.0 0.2 1.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.7 0.1 4.3 0.1 0.1 0.3 0.1 0.0 0.4 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 4.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 4.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.3 3.8 0.0 56.9 18.1 23.2 0.0 5.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 29.8 0.0 3.0 0.1 0.0 5.1 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.3 6.4 7.4 0.0 0.5 0.4 1.0 0.1 0.0 0.7 0.2 0.1 0.5 0.0 3.7 0.0 0.0 0.2 1.4 0.2 0.0 0.0 0.2 0.1 0.1 1.9 0.0 0.0 0.7 0.0 0.2 1.5 0.0 0.3 7.6 0.2 0.7 0.0 2.4 0.0 0.8 0.0 0.0 11.2 1.6 0.2 0.3 7.8 1.8 0.0 20.5 0.2 2.1 0.0 0.5 0.1 0.0 0.0 0.3 0.8 0.0 0.1 2.2 0.7 0.0 0.7 0.2 0.1 0.1 0.0 0.1 0.1 1.1 0.1 0.0 0.7 PADI2 "KIAA0994, PDI2" ENSG00000117115 "Peptidyl arginine deiminase 2" Q9Y2J8 1 17066761-17119451 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 240.6;skeletal muscle: 311.8;tongue: 492.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 95.9;Distal enterocytes: 178.7;Intestinal goblet cells: 77.3;Oligodendrocytes: 117.1;Paneth cells: 72.3" "Cancer enhanced" "Detected in many" "glioma: 24.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 43.3;neutrophil: 100.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 100.6" "Cell line enhanced" "Detected in some" "A549: 11.6;RPTEC TERT1: 33.1;SK-BR-3: 50.7;T-47d: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047735 Enhanced NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA047735: AB_2680139" "unprognostic (2.61e-2)" "unprognostic (3.60e-2)" "unprognostic (8.94e-3)" "unprognostic (1.57e-1)" "unprognostic (2.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.49e-1)" "unprognostic (3.74e-3)" "unprognostic (2.78e-3)" "unprognostic (3.28e-3)" "unprognostic (1.29e-1)" "unprognostic (3.07e-1)" "unprognostic (2.87e-1)" "unprognostic (3.64e-2)" "unprognostic (3.15e-1)" "unprognostic (2.27e-1)" "unprognostic (5.91e-3)" 2.1 0.9 85.9 9.3 161.5 23.7 41.1 164.3 103.9 3.3 33.5 89.8 1.4 0.8 0.6 6.1 2.7 1.6 0.6 82.2 165.1 12.7 0.7 4.4 1.0 205.8 167.0 0.2 1.5 2.1 3.7 1.4 212.0 2.6 92.3 50.5 44.4 1.6 311.8 9.6 8.4 5.8 189.3 13.4 2.2 0.8 144.3 2.1 0.6 492.3 1.3 2.5 1.0 240.6 0.0 11.6 0.1 0.0 0.0 0.0 0.7 0.3 0.0 0.1 0.1 0.1 4.9 0.2 1.5 0.5 0.1 1.6 0.4 0.1 0.3 0.0 0.8 0.5 0.0 0.0 0.0 0.7 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.9 3.8 0.6 1.4 1.6 3.9 0.0 0.0 0.0 0.4 33.1 0.0 2.1 0.2 0.0 50.7 0.0 2.7 13.9 2.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 1.9 0.0 1.3 16.2 43.3 0.0 0.9 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 100.6 0.0 0.2 0.4 0.0 6.4 85.9 161.5 164.3 103.9 82.2 165.1 205.8 167.0 212.0 189.3 144.3 240.6 0.2 0.0 1.3 28.4 1.0 0.3 0.4 0.6 0.0 2.2 31.2 32.5 0.4 0.0 3.3 1.8 95.9 0.2 0.7 178.7 11.7 0.6 6.1 0.0 0.0 8.2 3.6 0.0 1.5 0.0 0.5 0.6 0.0 0.1 17.1 0.5 0.7 0.0 7.2 0.0 1.4 77.3 2.0 4.8 25.8 10.3 0.3 9.2 28.4 15.9 33.8 33.6 0.0 13.6 117.1 0.0 72.3 0.7 0.4 0.5 15.0 0.3 0.2 29.6 0.0 5.6 1.3 0.2 0.4 0.0 0.4 0.1 0.4 0.0 51.8 0.2 PADI4 "PAD, PADI5, PDI4, PDI5" ENSG00000159339 "Peptidyl arginine deiminase 4" Q9UM07 1 17308195-17364004 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "bone marrow: 105.1;lymphoid tissue: 29.9" "Cell type enhanced" "Detected in some" "dendritic cells: 8.3;granulocytes: 12.6;Macrophages: 14.6;monocytes: 22.3;NK-cells: 20.6" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "basophil: 79.9;classical monocyte: 71.3;eosinophil: 97.5;neutrophil: 183.0" "Group enriched" "Detected in all" 9 "granulocytes: 183.0;monocytes: 71.3" "Cell line enhanced" "Detected in some" "HEL: 1.2;RPMI-8226: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017007, HPA042825" Enhanced NA NA 29000 "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA017007: AB_1854921, HPA042825: AB_2678189" "unprognostic (1.70e-1)" "unprognostic (2.25e-1)" "unprognostic (2.23e-1)" "unprognostic (2.98e-1)" "unprognostic (1.27e-1)" "unprognostic (1.13e-2)" "unprognostic (1.47e-1)" "unprognostic (4.91e-2)" "unprognostic (8.49e-2)" "unprognostic (5.22e-2)" "unprognostic (8.55e-2)" "unprognostic (1.81e-1)" "unprognostic (1.66e-3)" "unprognostic (1.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.56e-2)" "unprognostic (1.80e-1)" 1.8 0.1 0.2 0.7 0.4 105.1 0.3 0.2 0.8 0.1 0.2 0.1 0.1 0.1 0.0 0.4 1.0 0.4 1.1 0.3 0.2 0.5 1.7 7.9 0.3 0.3 0.1 0.1 0.3 0.0 0.2 0.5 0.3 0.2 0.0 0.0 0.2 0.0 0.2 0.2 0.2 0.4 0.0 29.9 0.4 0.1 0.1 1.6 0.3 0.3 0.2 0.7 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 79.9 71.3 97.5 0.4 5.7 0.2 1.1 0.5 0.7 13.9 1.8 2.6 4.5 183.0 4.5 1.8 6.2 0.4 35.8 0.2 0.4 0.2 0.8 0.3 0.2 0.3 0.1 0.3 0.0 0.1 0.4 0.0 0.0 3.7 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.4 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.3 0.6 0.0 0.6 0.6 0.0 0.0 12.6 0.1 0.0 0.4 0.2 0.0 0.4 0.0 0.0 3.3 0.4 0.2 0.0 14.6 0.0 0.0 22.3 0.0 20.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 4.0 0.0 0.0 0.1 2.3 0.1 0.0 0.0 PROK2 "BV8, KAL4, MIT1, PK2" ENSG00000163421 "Prokineticin 2" Q9HC23 3 71771655-71785206 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Biological rhythms" Neuropeptide "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 64.5;lymphoid tissue: 22.5" "Cell type enhanced" "Detected in some" "Erythroid cells: 5.9;Kupffer cells: 8.0;Macrophages: 11.3;monocytes: 6.9;Spermatocytes: 23.8" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.1" "Region enriched" "Detected in many" 7 "cerebral cortex: 13.3" "Immune cell enriched" "Detected in many" 50 "neutrophil: 414.4" "Lineage enriched" "Detected in many" 50 "granulocytes: 414.4" "Cell line enhanced" "Detected in some" "HL-60: 9.2;NB-4: 8.9;NTERA-2: 5.5;U-266/70: 12.0;U-266/84: 20.8;U-937: 8.3" "Group enriched" "Detected in some" 6 "basal ganglia: 2.7;hypothalamus: 1.1;olfactory bulb: 3.5" "Low region specificity" "Detected in all" HPA041408 Approved "Secreted to blood" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 16: U-266 - Nucleosome" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA041408: AB_10964057" "unprognostic (5.24e-2)" "unprognostic (3.13e-3)" "unprognostic (3.51e-3)" "unprognostic (3.59e-2)" "unprognostic (1.89e-1)" "unprognostic (2.94e-1)" "unprognostic (2.97e-2)" "unprognostic (9.52e-2)" "unprognostic (4.29e-2)" "unprognostic (9.91e-3)" "unprognostic (6.89e-2)" "unprognostic (5.73e-1)" "unprognostic (1.59e-4)" "unprognostic (2.02e-2)" "unprognostic (1.48e-1)" "unprognostic (1.40e-2)" "unprognostic (2.16e-2)" 7.2 0.3 0.7 17.7 0.5 64.5 0.3 0.1 13.3 0.4 0.7 0.4 0.3 0.2 0.0 0.4 2.7 1.2 1.0 0.2 0.5 0.6 2.5 13.1 0.2 0.5 1.0 0.2 1.1 0.0 0.4 3.1 1.2 0.2 0.2 0.1 0.3 0.0 0.5 0.1 0.5 1.5 0.2 22.5 0.6 11.4 1.9 1.1 0.5 4.2 0.5 6.0 0.4 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.3 1.6 0.0 0.0 0.0 0.3 8.9 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 20.8 0.0 0.0 8.3 0.0 0.0 8.2 3.5 3.4 0.7 0.0 0.0 2.7 2.9 0.7 0.0 0.9 5.0 414.4 0.0 0.2 0.3 1.7 3.1 0.7 0.5 0.1 13.3 0.2 0.5 0.5 1.0 1.2 0.2 1.9 0.7 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.6 1.8 0.0 0.0 2.5 0.0 0.0 0.0 1.6 0.1 0.1 0.1 0.0 5.9 0.0 0.0 0.0 0.9 0.0 0.0 1.3 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.0 8.0 0.3 2.8 0.3 11.3 1.8 0.0 6.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.1 23.8 2.9 0.0 0.0 0.0 3.5 0.1 0.0 0.0 RETN "ADSF, FIZZ3, RETN1" ENSG00000104918 Resistin Q9HD89 19 7669049-7670455 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Hormone "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 247.2" "Group enriched" "Detected in some" 6 "Hofbauer cells: 118.2;Kupffer cells: 47.0;Macrophages: 90.4;monocytes: 58.2" "Group enriched" "Detected in many" 4 "lung cancer: 2.6;pancreatic cancer: 4.8;thyroid cancer: 1.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "classical monocyte: 170.4;intermediate monocyte: 91.7;myeloid DC: 118.7;non-classical monocyte: 47.4" "Group enriched" "Detected in many" 11 "dendritic cells: 118.7;monocytes: 170.4" "Group enriched" "Detected in some" 11 "NB-4: 524.3;U-937: 243.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted to blood" NA NA 5120000 1200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (5.61e-2)" "unprognostic (6.20e-3)" "unprognostic (1.32e-2)" "unprognostic (3.04e-1)" "unprognostic (5.19e-4)" "unprognostic (1.53e-4)" "unprognostic (7.34e-2)" "unprognostic (3.35e-2)" "unprognostic (9.30e-2)" "unprognostic (1.35e-2)" "unprognostic (1.20e-1)" "unprognostic (4.02e-1)" "unprognostic (7.16e-5)" "unprognostic (4.23e-2)" "unprognostic (2.26e-1)" "unprognostic (8.91e-2)" "unprognostic (1.20e-1)" 3.4 1.0 0.1 5.2 0.1 247.2 1.4 0.0 0.9 0.6 0.0 0.8 6.1 0.7 0.0 0.5 2.4 0.3 2.3 0.4 0.1 1.7 3.3 34.0 0.1 0.1 0.1 0.4 0.9 0.1 0.5 1.1 0.1 1.0 0.2 0.0 1.1 0.0 0.6 0.7 0.7 4.3 0.0 53.3 1.0 0.2 0.0 4.0 0.8 0.0 0.0 0.6 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.7 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.9 524.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 243.2 0.0 0.1 170.4 0.1 0.4 91.7 1.2 0.0 1.9 1.5 118.7 0.1 4.4 9.0 13.6 0.3 47.4 4.5 0.0 64.3 0.1 0.1 0.0 0.9 0.4 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 12.8 9.9 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.0 0.0 1.1 0.6 0.0 0.0 3.8 0.0 0.4 0.1 118.2 0.0 0.0 0.0 0.0 47.0 8.7 0.2 0.0 90.4 0.0 0.0 58.2 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.1 0.0 0.5 1.5 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.1 2.2 0.0 0.0 0.1 RIPOR2 "C6orf32, DIFF48, FAM65B, KIAA0386, MYONAP" ENSG00000111913 "RHO family interacting cell polarization regulator 2" Q9Y4F9 6 24804282-25042170 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion, Chemotaxis, Differentiation, Hearing, Myogenesis" "Developmental protein, Signal transduction inhibitor" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 82.6" "Cell type enhanced" "Detected in many" "B-cells: 57.4;dendritic cells: 98.4;Respiratory ciliated cells: 83.1;Syncytiotrophoblasts: 82.8;T-cells: 38.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "neutrophil: 951.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 951.9" "Cell line enhanced" "Detected in many" "AF22: 30.9;Daudi: 73.5;fHDF/TERT166: 73.2;U-266/70: 25.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "unprognostic (4.05e-3)" "unprognostic (1.34e-3)" "unprognostic (3.55e-2)" "unprognostic (1.91e-2)" "unprognostic (1.47e-2)" "unprognostic (1.75e-2)" "unprognostic (5.89e-4)" "unprognostic (2.62e-2)" "unprognostic (1.54e-1)" "unprognostic (4.40e-3)" "unprognostic (1.64e-1)" "unprognostic (1.74e-2)" "unprognostic (8.55e-2)" "unprognostic (3.33e-2)" "unprognostic (2.30e-2)" "unprognostic (9.79e-2)" "unprognostic (1.14e-1)" 13.1 3.7 15.9 49.1 22.4 27.6 6.1 0.4 16.7 13.5 2.5 3.7 2.7 46.3 2.6 3.2 14.8 8.6 3.1 14.0 9.1 3.0 4.3 20.7 82.6 4.5 9.5 2.7 2.5 0.9 13.0 6.0 3.2 6.1 3.8 3.7 8.2 4.5 19.5 5.2 17.5 17.7 4.6 55.9 6.7 6.4 9.2 41.0 2.9 7.6 71.0 10.2 7.4 4.9 1.1 0.1 30.9 0.6 0.3 0.2 11.3 8.8 15.5 3.7 5.4 0.4 0.5 73.5 2.0 73.2 0.5 0.9 0.0 0.0 0.7 7.3 0.4 17.8 1.2 0.3 0.6 0.4 1.3 3.2 0.3 0.0 0.4 0.2 0.0 3.2 1.0 12.2 0.2 0.2 17.0 0.8 2.3 1.2 2.1 18.5 3.0 0.7 0.1 0.4 1.5 0.3 0.6 0.3 5.7 10.3 0.3 0.5 0.3 0.7 3.3 0.8 0.9 25.4 0.6 2.4 0.8 1.0 5.1 414.0 100.8 334.5 128.6 127.3 134.8 188.3 131.8 136.6 68.7 176.3 171.6 136.8 951.9 125.7 173.8 57.7 124.9 168.1 15.9 22.4 0.4 16.7 14.0 9.1 4.5 9.5 3.2 4.6 9.2 4.9 7.3 3.2 14.6 0.0 57.4 0.0 0.0 0.0 0.0 0.0 3.3 1.7 0.0 0.0 18.6 5.5 0.0 4.1 98.4 0.0 1.9 0.1 0.0 16.4 10.5 2.8 0.0 0.0 0.0 0.2 1.9 2.7 0.0 10.7 12.6 0.6 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 15.6 0.0 0.0 3.1 83.1 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 82.8 38.0 1.7 0.0 0.0 RNF175 FLJ34190 ENSG00000145428 "Ring finger protein 175" Q8N4F7 4 153710160-153760024 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.6;choroid plexus: 10.8" "Group enriched" "Detected in some" 5 "Early spermatids: 72.8;Excitatory neurons: 91.4;Inhibitory neurons: 95.7;Oligodendrocyte precursor cells: 38.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 8.8;HSkMC: 5.8;REH: 6.7;SH-SY5Y: 7.6;THP-1: 17.5;U-87 MG: 4.5" HPA035837 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 65: Brain - Ion transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA035837: AB_10601609" "unprognostic (3.23e-2)" "unprognostic (4.12e-2)" "unprognostic (3.34e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (3.11e-4)" "unprognostic (9.00e-2)" "unprognostic (2.65e-1)" "unprognostic (7.15e-4)" "unprognostic (1.17e-1)" "unprognostic (2.96e-3)" "unprognostic (6.30e-3)" "unprognostic (1.42e-1)" "unprognostic (3.63e-4)" "unprognostic (7.25e-3)" "unprognostic (3.27e-1)" "unprognostic (1.28e-1)" "unprognostic (7.66e-2)" 1.5 2.5 18.8 2.9 19.2 6.1 0.8 15.0 27.6 3.0 10.8 0.6 0.1 0.2 0.9 0.6 0.5 1.0 4.0 18.3 21.8 0.2 0.4 1.4 1.2 17.7 15.3 0.1 0.3 0.0 4.0 0.1 17.6 2.4 0.1 3.5 1.4 3.4 0.1 0.7 0.5 0.1 14.1 2.5 0.3 1.6 18.0 0.1 0.2 0.5 0.6 0.5 1.5 17.5 0.2 0.0 8.8 0.0 0.0 0.6 0.0 0.0 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 5.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 3.0 0.0 0.0 6.7 0.0 0.3 0.0 0.1 0.0 7.6 0.0 0.0 0.2 0.1 0.0 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.9 0.0 0.0 1.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.9 0.0 2.2 0.0 2.4 0.0 2.1 0.0 0.6 0.6 18.8 19.2 15.0 27.6 18.3 21.8 17.7 15.3 17.6 14.1 18.0 17.5 0.1 0.0 0.5 6.8 0.0 0.4 0.1 0.6 0.6 0.7 0.1 0.6 4.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 72.8 0.0 0.1 0.2 0.0 0.4 91.4 0.0 0.0 2.9 0.0 0.2 0.0 0.4 0.0 0.0 0.5 0.0 95.7 0.0 0.0 5.9 2.9 14.6 0.0 1.5 1.8 2.8 0.7 0.8 0.0 38.7 2.8 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.7 1.6 0.0 0.0 0.3 1.5 1.3 0.0 0.3 0.0 0.6 0.0 0.0 0.2 S100A12 "CAAF1, CAGC, CGRP, ENRAGE, MRP6, p6" ENSG00000163221 "S100 calcium binding protein A12" P80511 1 153373711-153375621 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Antibiotic, Antimicrobial, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 3489.7" "Group enriched" "Detected in many" 20 "Kupffer cells: 711.7;Macrophages: 475.0;monocytes: 998.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 51.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "classical monocyte: 1321.1;neutrophil: 1781.4" "Group enriched" "Detected in many" 13 "granulocytes: 1781.4;monocytes: 1321.1" "Cell line enhanced" "Detected in some" "hTCEpi: 2.6;THP-1: 1.6" "Region enhanced" "Detected in some" "cerebral cortex: 4.0" "HPA002881, CAB025872" Enhanced "Secreted to blood" NA NA 28500000 8300000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "CAB025872: , HPA002881: AB_1848175" "unprognostic (1.33e-1)" "unprognostic (4.51e-2)" "unprognostic (7.49e-2)" "unprognostic (1.36e-1)" "unprognostic (7.30e-2)" "unprognostic (4.36e-2)" "unprognostic (3.79e-2)" "unprognostic (8.79e-3)" "unprognostic (9.04e-2)" "unprognostic (3.14e-2)" "unprognostic (1.58e-1)" "unprognostic (8.08e-3)" "prognostic unfavorable (5.03e-4)" "unprognostic (3.68e-3)" "unprognostic (1.05e-1)" "unprognostic (1.31e-2)" "unprognostic (7.70e-2)" 54.9 3.2 2.6 82.0 3.1 3489.7 7.0 2.9 7.7 21.9 3.2 5.5 1.7 2.1 0.0 52.4 19.3 6.7 16.6 2.7 2.6 15.2 25.6 148.4 1.9 3.2 2.9 2.1 3.6 1.3 4.3 19.8 3.9 3.5 0.4 0.3 11.4 0.2 4.0 3.7 4.4 40.4 3.0 523.2 8.9 0.9 2.9 30.2 6.0 14.8 46.5 41.9 33.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 1321.1 5.2 1.9 44.9 1.0 3.2 0.8 1.5 122.7 1.0 1.1 0.5 1781.4 0.4 9.6 8.3 2.0 1031.8 2.6 3.1 2.9 7.7 2.7 2.6 3.2 2.9 3.9 3.0 2.9 2.9 0.0 19.2 24.4 0.0 6.1 0.1 0.3 9.8 0.0 0.0 0.1 0.0 1.1 8.6 9.2 1.8 0.0 0.5 2.9 0.0 0.0 0.1 1.4 0.0 0.0 2.1 0.0 14.1 0.1 0.2 0.9 4.1 1.1 0.0 13.9 0.0 6.8 3.8 8.6 0.0 0.1 0.0 0.0 711.7 0.8 1.8 0.0 475.0 0.0 1.0 998.3 0.0 36.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 1.7 7.8 0.0 0.0 0.8 0.4 0.0 0.2 5.7 0.0 0.5 6.9 0.0 0.1 0.2 S100A8 "60B8AG, CAGA, CFAG, CGLA, MRP8, P8" ENSG00000143546 "S100 calcium binding protein A8" P05109 1 153390032-153391073 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity" Antimicrobial "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 35382.0;esophagus: 24565.6;vagina: 11166.4" "Group enriched" "Detected in many" 7 "Basal respiratory cells: 4126.5;Kupffer cells: 6348.0;Macrophages: 3758.3;monocytes: 6932.6;Squamous epithelial cells: 8480.1" "Cancer enhanced" "Detected in all" "cervical cancer: 2290.9;head and neck cancer: 2382.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 9 "classical monocyte: 26833.7;neutrophil: 52973.6" "Group enriched" "Detected in all" 9 "granulocytes: 52973.6;monocytes: 26833.7" "Group enriched" "Detected in some" 24 "hTCEpi: 241.8;SK-BR-3: 719.0;THP-1: 400.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB002791, HPA024372" Enhanced Supported "Intermediate filaments,Cytosol" "Secreted to blood" NA NA 10900000 370000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Intermediate filaments" Cytosol "CAB002791: , HPA024372: AB_1856536" "unprognostic (1.98e-1)" "unprognostic (1.13e-1)" "unprognostic (3.79e-2)" "unprognostic (1.58e-2)" "unprognostic (8.60e-3)" "unprognostic (9.26e-3)" "unprognostic (4.92e-2)" "unprognostic (1.32e-1)" "unprognostic (1.83e-1)" "unprognostic (6.13e-2)" "unprognostic (3.77e-2)" "unprognostic (2.24e-2)" "prognostic unfavorable (8.94e-7)" "unprognostic (1.17e-1)" "unprognostic (8.90e-2)" "unprognostic (8.27e-2)" "unprognostic (8.94e-3)" 582.3 54.3 41.7 1245.8 45.6 35382.0 70.0 43.4 88.0 5650.6 45.5 55.2 15.4 23.1 5.5 24565.6 236.1 99.0 121.1 40.9 42.7 103.0 176.7 1061.7 29.5 47.7 44.8 25.8 52.0 9.6 41.7 205.8 50.7 43.1 14.7 5.6 3988.2 5.0 48.5 267.3 47.7 430.2 44.2 3239.5 93.8 16.2 45.5 281.3 48.8 174.8 8952.6 561.9 11166.4 46.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.0 1.3 0.0 0.3 12.4 0.0 18.7 0.0 0.1 0.0 3.5 0.0 0.0 0.0 5.6 0.1 0.0 241.8 0.0 7.5 0.0 0.0 0.0 9.6 1.2 0.0 0.9 0.4 1.5 0.3 0.0 0.0 0.4 5.8 1.0 0.0 0.0 0.4 0.5 3.6 719.0 0.0 0.0 4.7 400.6 10.6 0.0 0.2 0.9 0.1 0.2 1.3 2.7 0.3 13.9 0.0 848.0 26833.7 3023.7 33.4 1999.2 49.2 57.2 21.8 18.2 4686.1 23.5 21.6 23.3 52973.6 27.1 493.1 188.1 37.1 24979.9 41.7 45.6 43.4 88.0 40.9 42.7 47.7 44.8 50.7 44.2 45.5 46.2 1.1 224.4 489.8 0.0 77.2 19.6 3.5 4126.5 50.7 0.0 13.2 3.9 10.0 70.1 817.0 14.7 0.0 5.8 67.1 0.3 0.0 1.0 210.7 0.5 0.6 33.1 0.0 143.5 0.0 0.9 8.5 61.3 1.1 0.5 227.1 0.1 76.1 54.6 417.5 0.0 0.0 0.2 207.5 6348.0 5.1 172.4 4.1 3758.3 0.0 0.0 6932.6 0.0 289.4 0.0 0.0 1.4 0.0 1.5 26.1 0.9 0.0 25.0 162.8 0.0 0.0 7.7 32.3 2.1 1.0 8480.1 113.2 6.7 91.4 0.0 0.0 31.3 S100A9 "60B8AG, CAGB, CFAG, CGLB, LIAG, MAC387, MIF, MRP14, NIF, P14" ENSG00000163220 "S100 calcium binding protein A9" P06702 1 153357854-153361023 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity" "Antimicrobial, Antioxidant" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 32194.3;esophagus: 30581.7;vagina: 14027.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 5771.3;Kupffer cells: 7537.0;Macrophages: 3678.1;monocytes: 11103.1;Squamous epithelial cells: 3263.1" "Cancer enhanced" "Detected in all" "cervical cancer: 5468.0;head and neck cancer: 6692.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 24579.6;neutrophil: 33654.0" "Group enriched" "Detected in all" 6 "granulocytes: 33654.0;monocytes: 24579.6" "Cell line enriched" "Detected in many" 6 "SK-BR-3: 2398.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004193, CAB009441" Enhanced Supported "Nucleoplasm,Cell Junctions,Cytosol" "Secreted to blood" NA NA 10600000 1200000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cell Junctions, Cytosol" "CAB009441: AB_2184420, HPA004193: AB_1856537" "unprognostic (1.72e-1)" "unprognostic (3.33e-2)" "unprognostic (2.40e-1)" "unprognostic (3.94e-3)" "unprognostic (1.36e-2)" "unprognostic (5.45e-3)" "prognostic unfavorable (1.13e-6)" "unprognostic (1.10e-2)" "unprognostic (4.31e-1)" "unprognostic (3.06e-1)" "unprognostic (1.35e-2)" "unprognostic (5.59e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.48e-1)" "unprognostic (7.52e-2)" "unprognostic (5.39e-2)" "unprognostic (1.75e-2)" 706.4 126.1 19.7 1505.7 24.3 32194.3 189.8 21.4 67.8 7849.1 28.5 123.9 24.1 50.0 2.0 30581.7 486.1 147.4 208.5 19.4 21.9 171.7 284.0 1629.4 69.3 28.7 24.2 51.5 73.9 11.5 65.4 370.1 30.0 91.3 20.2 3.6 5790.0 9.6 92.2 416.7 120.6 480.7 22.0 5381.4 187.6 16.7 26.5 197.7 90.4 150.4 4378.8 955.1 14027.7 25.4 24.6 0.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.5 0.0 9.2 372.2 0.0 0.4 23.0 0.0 157.3 0.0 0.4 0.0 6.2 0.0 0.1 0.0 7.8 0.0 0.0 130.2 0.0 8.4 0.0 0.0 0.1 7.6 3.5 0.0 31.4 0.8 3.3 0.1 3.1 0.2 0.8 5.1 82.2 0.3 100.4 1.3 0.6 4.0 2398.2 1.7 1.2 38.1 312.3 6.8 0.0 3.3 0.4 0.4 0.7 1.6 3.3 0.5 71.7 0.0 373.8 24579.6 2626.3 30.5 1754.8 52.6 29.7 25.3 17.2 4664.8 24.8 17.7 15.4 33654.0 18.8 860.2 153.3 29.2 24461.7 19.7 24.3 21.4 67.8 19.4 21.9 28.7 24.2 30.0 22.0 26.5 25.4 1.8 230.8 392.4 0.0 92.1 20.0 123.1 5771.3 28.5 0.0 55.6 6.7 8.0 57.2 1685.0 36.8 0.0 126.1 115.1 7.7 5.9 102.6 1.7 1.2 1.9 26.9 0.0 92.8 0.0 39.4 52.9 50.9 3.6 9.4 164.0 0.2 70.6 54.5 1926.0 0.0 0.0 3.7 309.3 7537.0 13.4 4.0 5.9 3678.1 0.0 0.0 11103.1 0.0 483.0 0.0 0.0 15.3 1.4 0.0 13.1 55.6 0.8 25.2 262.8 0.3 0.0 13.3 60.4 0.3 1.2 3263.1 33.2 1236.0 79.9 0.0 12.5 551.3 S100P ENSG00000163993 "S100 calcium binding protein P" P25815 4 6693878-6697170 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 1410.7;stomach 1: 1742.0;urinary bladder: 1777.0" "Cell type enhanced" "Detected in many" "Club cells: 1088.3;Gastric mucus-secreting cells: 2306.9;Syncytiotrophoblasts: 2773.6;Urothelial cells: 4448.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 564.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 46 "basophil: 1789.3;eosinophil: 836.9;neutrophil: 2961.8" "Lineage enriched" "Detected in many" 73 "granulocytes: 2961.8" "Cell line enhanced" "Detected in many" "BEWO: 879.0;Hep G2: 1283.2;hTCEpi: 1185.6;OE19: 4335.4;RT4: 2619.8;SK-BR-3: 1057.4" "HPA019502, HPA075251" Enhanced Supported Nucleoplasm NA NA 1600000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA019502: AB_1856530, HPA075251: " "unprognostic (1.46e-1)" "unprognostic (1.50e-1)" "unprognostic (7.52e-2)" "unprognostic (1.44e-1)" "unprognostic (2.22e-1)" "unprognostic (7.34e-2)" "unprognostic (1.60e-3)" "unprognostic (3.92e-2)" "unprognostic (7.19e-2)" "unprognostic (9.24e-2)" "prognostic unfavorable (2.00e-4)" "unprognostic (3.87e-2)" "unprognostic (1.96e-2)" "unprognostic (1.72e-1)" "unprognostic (9.24e-2)" "unprognostic (3.65e-1)" "unprognostic (1.12e-2)" 14.0 1.7 1.0 42.4 1.4 1410.7 7.4 1.6 6.3 15.0 1.4 155.6 13.2 5.9 0.0 340.6 6.9 52.1 2.7 1.4 0.9 2.1 8.8 14.7 1.0 1.1 1.1 0.5 4.7 0.4 1.7 474.7 3.2 25.5 176.0 0.1 8.2 0.5 0.4 20.9 23.8 16.6 0.6 34.3 1742.0 1.4 1.0 10.6 0.6 12.2 96.9 1777.0 34.5 1.1 115.2 89.1 0.0 0.1 0.0 0.5 879.0 0.0 1.0 0.0 0.0 5.2 17.6 0.7 40.1 0.6 1.2 137.6 0.5 1.1 0.0 54.7 0.0 1.9 106.7 1283.2 0.0 53.4 3.2 0.6 1185.6 0.0 1.1 0.2 0.2 0.8 3.1 0.0 0.0 214.5 1.6 126.5 1.5 4335.4 149.6 0.9 0.5 0.5 0.0 2619.8 1.1 0.7 156.8 1057.4 2.4 39.9 31.0 169.6 0.5 0.0 1.4 0.2 0.9 1.2 0.7 0.8 0.1 479.1 0.2 1789.3 40.6 836.9 1.4 9.5 1.1 0.4 1.7 1.1 1.6 0.5 0.3 0.8 2961.8 0.1 5.7 0.4 1.1 16.7 1.0 1.4 1.6 6.3 1.4 0.9 1.1 1.1 3.2 0.6 1.0 1.1 0.9 9.6 48.6 0.0 6.2 1.1 318.3 568.6 4.0 0.0 3.4 3.6 1.2 27.1 1088.3 1.8 0.0 550.7 2.2 322.2 0.0 4.8 12.3 37.5 38.9 8.7 16.6 0.0 0.0 31.1 783.4 13.8 2306.9 202.5 31.6 0.0 1.4 7.4 69.2 0.0 0.0 443.7 152.5 11.8 1.0 7.4 0.0 11.0 8.8 0.0 5.6 0.0 2.1 0.0 0.1 828.1 580.9 0.0 5.9 288.4 2.2 0.5 301.5 0.0 0.0 0.1 32.1 0.5 0.6 18.6 6.3 2773.6 9.8 0.1 173.2 4448.3 SBNO2 "FLJ00173, KIAA0963, Sno, Stno" ENSG00000064932 "Strawberry notch homolog 2" Q9Y2G9 19 1107637-1174268 "Predicted intracellular proteins" "Differentiation, Osteogenesis, Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "neutrophil: 2.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 2.5" "Cell line enhanced" "Detected in many" "A-431: 45.3;HDLM-2: 65.2;U-266/70: 49.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041867 Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 72: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" "HPA041867: AB_2677715" "unprognostic (1.62e-1)" "unprognostic (1.18e-1)" "unprognostic (1.85e-1)" "unprognostic (6.20e-3)" "unprognostic (4.68e-2)" "unprognostic (8.48e-3)" "unprognostic (1.19e-2)" "unprognostic (1.64e-2)" "unprognostic (1.70e-1)" "unprognostic (1.58e-3)" "unprognostic (3.22e-2)" "unprognostic (2.47e-1)" "prognostic unfavorable (7.98e-8)" "unprognostic (1.34e-2)" "unprognostic (5.67e-2)" "unprognostic (1.35e-1)" "unprognostic (1.88e-1)" 61.3 42.8 2.8 8.5 2.9 11.4 40.2 1.8 5.0 35.7 4.6 31.8 1.9 28.0 0.2 51.8 33.8 3.0 27.1 0.9 3.2 57.8 41.5 68.4 2.7 12.0 5.4 30.9 21.4 0.2 37.8 2.4 5.4 42.7 0.3 0.1 42.9 0.7 38.6 43.0 30.8 2.1 3.5 60.0 30.0 19.3 8.6 1.5 34.2 0.5 2.5 32.1 35.7 5.5 45.3 5.7 0.8 0.5 0.1 2.8 16.1 13.0 1.4 2.9 1.6 0.3 7.3 9.0 18.2 2.2 2.3 14.6 0.0 2.0 1.0 65.2 9.8 9.9 18.3 0.1 2.4 5.8 28.7 6.8 1.8 4.3 1.7 2.2 2.8 3.9 15.3 12.4 1.1 5.5 5.7 7.4 12.3 0.9 19.1 13.1 7.9 11.0 4.0 2.1 10.3 16.1 7.9 14.2 15.8 1.1 5.0 4.6 15.0 7.9 6.2 23.6 22.1 49.0 24.8 7.8 15.7 5.3 9.0 0.0 0.3 0.1 0.1 0.2 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 2.5 0.1 0.1 0.1 0.0 0.1 2.8 2.9 1.8 5.0 0.9 3.2 12.0 5.4 5.4 3.5 8.6 5.5 28.8 9.6 22.8 4.6 8.8 14.9 13.2 10.7 11.4 5.7 39.7 23.9 5.4 5.7 18.8 3.7 2.1 4.7 13.2 22.3 3.9 9.4 2.8 19.3 21.9 25.3 3.0 0.4 4.4 6.8 5.7 13.1 33.6 39.1 3.8 10.4 13.9 10.8 10.3 6.7 3.4 10.2 14.2 15.9 20.7 1.6 9.3 20.2 8.8 5.6 13.0 3.3 5.2 3.5 5.8 17.9 15.1 4.1 16.2 20.8 7.9 1.8 14.5 4.9 6.6 12.0 12.9 7.7 9.0 10.6 18.8 10.9 14.4 9.5 12.3 22.1 SELL "CD62L, hLHRc, LAM-1, LAM1, Leu-8, LNHR, LSEL, Lyam-1, LYAM1, PLNHR" ENSG00000188404 "Selectin L" P14151 1 169690665-169711702 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 150.4;lymphoid tissue: 231.4" "Group enriched" "Detected in many" 5 "B-cells: 221.4;dendritic cells: 206.0;Kupffer cells: 68.9;Macrophages: 86.3;monocytes: 208.7;NK-cells: 110.2;T-cells: 104.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 11.2;JURKAT: 29.4;MOLT-4: 21.2;U-266/70: 38.8;U-698: 19.4;U-937: 11.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002144, HPA051972" Enhanced Uncertain Cytosol NA NA 4700000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "CAB002144: AB_563862, HPA051972: AB_2797242" "prognostic favorable (3.76e-4)" "prognostic favorable (2.25e-4)" "unprognostic (1.52e-2)" "unprognostic (2.89e-2)" "unprognostic (7.87e-3)" "prognostic favorable (6.43e-4)" "unprognostic (1.39e-3)" "unprognostic (3.43e-1)" "unprognostic (2.70e-3)" "prognostic favorable (3.14e-4)" "unprognostic (1.42e-1)" "unprognostic (4.21e-2)" "prognostic unfavorable (4.96e-5)" "unprognostic (4.76e-2)" "unprognostic (8.71e-3)" "unprognostic (9.57e-2)" "unprognostic (1.01e-1)" 29.3 2.3 2.8 118.8 4.5 150.4 2.6 8.4 6.2 3.7 2.7 6.8 3.2 2.6 1.7 5.5 4.7 24.1 3.1 3.2 4.0 3.0 12.1 19.4 231.4 7.4 4.5 1.0 3.7 28.0 13.9 11.2 6.1 3.7 7.1 1.0 3.8 1.9 3.4 0.6 17.0 14.5 6.4 166.8 5.6 1.1 3.9 132.2 2.8 13.6 202.0 37.9 1.4 8.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.2 0.2 0.7 0.0 0.3 11.2 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 7.7 1.3 0.5 0.0 0.0 0.0 0.0 1.8 29.4 0.1 1.4 0.0 1.8 21.2 0.3 0.1 0.4 0.3 7.8 0.2 0.7 6.1 0.3 0.0 0.0 0.0 1.4 0.0 0.8 0.0 0.0 0.0 0.6 0.2 0.0 0.0 38.8 0.0 19.4 2.0 11.1 0.3 3688.4 992.6 1696.7 284.3 211.6 78.1 613.0 528.9 294.2 756.3 734.4 1169.2 683.6 4201.4 2551.1 93.1 622.9 1011.2 2052.5 2.8 4.5 8.4 6.2 3.2 4.0 7.4 4.5 6.1 6.4 3.9 8.0 1.8 9.6 13.7 0.7 221.4 0.4 0.3 0.0 0.6 0.1 0.5 0.3 0.6 2.8 1.8 11.0 0.0 13.9 206.0 0.1 0.0 0.2 0.0 0.1 0.0 3.4 0.0 25.2 0.2 0.0 0.6 3.3 2.6 0.1 10.1 0.5 3.9 1.1 5.6 0.0 0.1 0.1 0.0 68.9 2.7 0.2 0.6 86.3 1.8 1.0 208.7 2.5 110.2 0.0 0.8 0.1 0.0 0.0 25.8 0.0 0.0 0.9 1.5 0.0 0.0 0.2 0.6 0.0 0.1 0.3 0.1 28.5 104.9 0.5 0.0 0.6 SIGLEC5 "CD170, CD33L2, OB-BP2, SIGLEC-5" ENSG00000105501 "Sialic acid binding Ig like lectin 5" O15389 19 51611927-51645545 "CD markers, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 14.7;lymphoid tissue: 12.4" "Cell type enhanced" "Detected in some" "granulocytes: 8.2;Hofbauer cells: 5.6;Kupffer cells: 10.4;Macrophages: 4.4;monocytes: 3.0" "Cancer enriched" "Detected in single" 5 "urothelial cancer: 1.7" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 4 "neutrophil: 152.5;non-classical monocyte: 49.3" "Group enriched" "Detected in many" 6 "granulocytes: 152.5;monocytes: 49.3" "Group enriched" "Detected in some" 5 "HMC-1: 59.2;U-937: 25.6" "HPA009085, CAB024900" Supported NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB024900: , HPA009085: AB_1079965" "unprognostic (1.83e-1)" "unprognostic (1.94e-1)" "unprognostic (2.02e-2)" "unprognostic (1.03e-2)" "unprognostic (4.39e-2)" "unprognostic (1.62e-2)" "unprognostic (1.73e-1)" "unprognostic (1.01e-1)" "unprognostic (3.28e-1)" "unprognostic (7.44e-2)" "unprognostic (1.01e-1)" "unprognostic (4.05e-1)" "unprognostic (3.71e-4)" "unprognostic (4.37e-2)" "unprognostic (3.55e-3)" "unprognostic (4.02e-1)" "unprognostic (1.95e-1)" 1.4 0.4 0.3 6.6 0.6 14.7 0.2 0.3 1.2 0.2 0.0 0.7 0.1 0.3 0.0 0.3 0.7 0.7 0.4 0.3 0.3 0.3 1.5 3.4 3.1 0.4 0.3 0.1 0.2 0.3 0.1 0.8 0.5 0.3 0.7 0.2 0.3 0.1 0.0 0.0 2.0 0.9 0.4 12.4 0.6 0.8 0.4 0.7 0.2 0.4 2.2 1.5 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 59.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.6 0.0 15.5 22.2 0.5 0.0 24.2 0.0 2.5 0.0 0.0 15.6 2.0 0.0 0.0 152.5 0.7 49.3 5.0 0.0 8.4 0.3 0.6 0.3 1.2 0.3 0.3 0.4 0.3 0.5 0.4 0.4 0.6 0.0 0.0 0.0 0.3 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.3 0.0 0.0 8.2 0.0 0.0 0.0 5.6 0.0 0.2 0.0 0.0 10.4 1.2 0.5 0.3 4.4 0.0 1.0 3.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 SIRPB1 "CD172b, SIRP-BETA-1" ENSG00000101307 "Signal regulatory protein beta 1" "O00241, Q5TFQ8" 20 1561385-1620061 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 52.2;lung: 19.4;lymphoid tissue: 28.6" "Cell type enhanced" "Detected in some" "dendritic cells: 10.9;Hofbauer cells: 14.7;Kupffer cells: 29.4;Macrophages: 30.9;monocytes: 26.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "neutrophil: 1594.8" "Group enriched" "Detected in all" 6 "granulocytes: 1594.8;monocytes: 502.2" "Group enriched" "Detected in some" 4 "HMC-1: 54.0;NB-4: 76.2;THP-1: 58.9" HPA047463 Uncertain Uncertain Vesicles,Centrosome NA NA 44000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles Centrosome "HPA047463: AB_2680057" "unprognostic (1.88e-2)" "unprognostic (6.19e-2)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (5.38e-2)" "unprognostic (1.60e-1)" "unprognostic (4.40e-2)" "unprognostic (7.18e-2)" "unprognostic (4.11e-3)" "unprognostic (9.12e-2)" "unprognostic (6.31e-2)" "unprognostic (4.57e-2)" "unprognostic (2.65e-3)" "unprognostic (5.76e-2)" "unprognostic (2.39e-3)" "unprognostic (5.00e-3)" "unprognostic (1.19e-2)" 5.4 1.6 1.3 28.6 1.3 52.2 1.9 1.2 4.2 1.2 0.1 2.1 1.5 0.8 0.8 1.3 2.2 11.2 1.6 1.4 0.8 1.2 3.1 19.4 11.0 0.7 0.8 0.7 1.3 0.3 0.6 2.8 1.3 0.8 1.8 1.2 1.7 0.9 0.8 0.8 2.8 3.2 0.9 24.5 1.5 0.6 2.1 4.5 0.9 1.5 4.3 8.1 0.8 1.9 0.2 0.0 0.2 0.1 0.3 0.5 0.2 0.4 0.1 0.2 0.0 0.2 0.1 0.1 0.8 0.4 7.1 0.3 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.2 14.9 54.0 0.1 0.2 0.3 0.0 8.0 0.5 1.1 0.0 0.2 0.4 0.1 0.0 76.2 0.2 0.0 3.3 0.2 0.0 0.1 10.8 0.3 0.1 0.2 0.2 0.0 0.5 0.0 0.0 58.9 1.6 0.7 0.1 0.4 0.3 0.1 0.1 0.1 1.1 13.4 0.2 6.1 502.2 868.9 7.3 419.7 10.3 2.8 6.5 5.7 175.2 3.4 8.8 5.5 1594.8 8.2 357.6 165.7 11.8 287.0 1.3 1.3 1.2 4.2 1.4 0.8 0.7 0.8 1.3 0.9 2.1 1.9 0.6 3.2 5.2 0.3 1.2 0.0 0.1 0.2 0.6 0.2 0.1 0.0 0.5 0.0 1.6 0.0 0.0 0.2 10.9 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 1.3 0.3 0.0 0.1 0.7 0.0 0.2 7.0 0.0 1.8 0.2 14.7 0.0 0.1 0.0 0.0 29.4 0.0 0.0 0.0 30.9 0.0 0.0 26.7 0.1 0.0 0.5 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 1.8 0.0 0.0 0.0 SLC11A1 "LSH, NRAMP, NRAMP1" ENSG00000018280 "Solute carrier family 11 member 1" P49279 2 218382029-218396894 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 78.6;lymphoid tissue: 46.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 108.0;Kupffer cells: 166.8;Macrophages: 209.4;monocytes: 101.2" "Cancer enhanced" "Detected in many" "glioma: 7.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "classical monocyte: 6.1;intermediate monocyte: 4.5;myeloid DC: 1.9;neutrophil: 4.1;non-classical monocyte: 6.0" "Group enriched" "Detected in many" 11 "dendritic cells: 1.9;granulocytes: 4.1;monocytes: 6.1" "Cell line enhanced" "Detected in some" "HEL: 1.2;HMC-1: 1.0" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA029590, HPA050378, HPA068540" Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Mitochondria Nucleoli "HPA029590: AB_10794613, HPA050378: , HPA068540: " "unprognostic (2.64e-1)" "unprognostic (3.05e-2)" "unprognostic (1.46e-2)" "unprognostic (2.34e-2)" "unprognostic (1.99e-2)" "unprognostic (3.83e-2)" "unprognostic (1.04e-3)" "unprognostic (2.06e-1)" "unprognostic (1.14e-1)" "unprognostic (1.58e-2)" "unprognostic (7.29e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (2.58e-8)" "unprognostic (9.55e-2)" "unprognostic (3.50e-2)" "unprognostic (1.78e-2)" "unprognostic (1.08e-2)" 14.1 8.5 3.5 7.1 4.3 6.7 4.9 3.9 11.1 2.7 4.7 3.5 0.2 2.2 0.1 1.6 7.4 1.0 8.0 3.3 5.0 3.4 5.1 78.6 0.2 7.4 5.2 1.7 3.2 0.3 3.1 2.7 6.9 3.2 0.0 0.6 3.2 0.1 1.7 1.5 2.2 1.9 5.2 46.6 3.0 0.9 17.3 0.3 2.7 1.3 0.0 7.2 2.4 7.4 0.1 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 1.2 0.2 0.2 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.2 0.0 0.4 0.0 0.9 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.3 6.1 0.6 0.3 4.5 0.2 0.1 0.2 0.1 1.9 0.2 0.3 0.2 4.1 0.2 6.0 0.2 0.2 2.0 3.5 4.3 3.9 11.1 3.3 5.0 7.4 5.2 6.9 5.2 17.3 7.4 1.5 22.4 38.5 1.6 4.1 0.9 4.3 1.9 1.2 3.1 4.5 4.6 8.6 2.8 13.8 9.2 0.0 1.8 3.1 1.8 9.8 1.3 1.8 6.1 2.3 17.0 1.2 1.7 1.3 2.1 7.8 5.8 2.0 2.8 25.3 0.9 6.8 7.3 108.0 1.7 0.9 4.0 6.1 166.8 6.3 0.5 2.1 209.4 1.8 4.7 101.2 12.9 10.3 0.5 1.4 0.4 1.6 0.7 5.6 3.9 2.5 11.7 11.0 3.3 19.7 2.9 4.2 0.8 1.8 2.1 1.0 8.1 6.7 3.3 2.9 3.3 SOCS3 "CIS3, Cish3, SOCS-3, SSI-3" ENSG00000184557 "Suppressor of cytokine signaling 3" O14543 17 78356778-78360077 "Disease related genes, Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 501.5" "Cell type enhanced" "Detected in many" "Adipocytes: 989.2;Endothelial cells: 635.9;Fibroblasts: 394.4;Langerhans cells: 381.5;Skeletal myocytes: 485.9;Smooth muscle cells: 381.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 9.5" "Group enriched" "Detected in many" 6 "granulocytes: 9.5;T-cells: 3.1" "Cell line enhanced" "Detected in many" "HDLM-2: 154.2;HSkMC: 73.3;U-266/70: 76.0" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "spinal cord: 9.8" "CAB012220, HPA068569" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Plasma membrane" "CAB012220: AB_443287, HPA068569: AB_2686008" "prognostic favorable (4.80e-4)" "unprognostic (2.67e-1)" "unprognostic (5.05e-2)" "unprognostic (1.64e-3)" "unprognostic (4.41e-3)" "unprognostic (2.48e-3)" "unprognostic (1.81e-1)" "unprognostic (1.46e-1)" "unprognostic (6.88e-2)" "unprognostic (9.61e-3)" "unprognostic (1.84e-1)" "unprognostic (2.00e-2)" "prognostic unfavorable (9.34e-9)" "unprognostic (1.08e-2)" "unprognostic (8.80e-2)" "unprognostic (7.59e-3)" "unprognostic (8.40e-2)" 501.5 50.3 19.1 99.0 20.2 126.4 114.1 18.8 27.5 35.1 21.7 119.0 19.4 53.4 1.9 72.7 306.5 190.4 76.8 16.8 21.2 72.1 84.2 234.8 46.9 43.1 22.1 55.5 46.2 23.6 55.7 77.5 24.6 61.8 27.2 4.2 36.3 17.1 26.1 55.3 64.2 125.2 23.7 52.0 123.9 5.9 32.2 115.9 54.1 37.1 11.8 187.9 31.6 19.6 6.4 10.2 7.3 3.8 2.8 44.3 19.1 31.4 28.3 32.1 13.6 6.6 4.4 0.2 6.7 7.5 20.4 2.0 1.5 3.1 12.7 154.2 0.9 5.8 24.1 1.4 14.5 0.1 2.7 73.3 2.6 24.9 9.3 19.4 14.0 0.5 17.4 58.2 15.1 3.3 3.3 1.0 5.2 1.2 12.8 0.2 36.9 1.1 51.4 6.3 0.3 4.6 9.5 2.5 1.3 26.8 2.9 1.4 8.4 62.7 17.6 22.2 18.4 76.0 46.9 0.1 51.6 0.8 4.1 0.0 1.0 0.2 0.8 0.1 1.9 0.0 2.1 0.9 1.1 0.0 3.1 0.6 9.5 0.3 0.0 1.0 1.3 0.5 19.1 20.2 18.8 27.5 16.8 21.2 43.1 22.1 24.6 23.7 32.2 19.6 989.2 48.1 125.6 0.7 64.7 164.3 120.7 75.0 125.2 1.0 176.3 136.4 23.1 18.6 51.7 38.6 2.1 14.9 42.1 20.5 5.9 44.4 0.8 106.7 207.6 635.9 33.0 11.6 0.0 38.6 46.0 394.4 125.4 166.8 36.0 5.8 307.3 20.2 94.6 0.0 0.1 25.0 30.5 78.4 381.5 1.7 78.3 231.0 85.4 1.0 33.6 7.7 1.0 0.0 1.0 43.0 28.1 2.2 115.5 72.0 24.3 11.5 38.1 2.7 13.1 485.9 381.7 0.4 1.0 36.3 133.0 62.1 88.7 5.3 41.0 90.5 SRGN "PPG, PRG, PRG1" ENSG00000122862 Serglycin P10124 10 69088103-69104805 "Plasma proteins, Predicted secreted proteins" "Apoptosis, Biomineralization" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "bone marrow: 8096.7" "Cell type enhanced" "Detected in many" "dendritic cells: 2922.2;granulocytes: 2343.1;Kupffer cells: 1789.9;Langerhans cells: 6618.2;Macrophages: 3639.1;monocytes: 3188.2;Plasma cells: 1740.9;T-cells: 2235.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 5714.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 5714.1" "Cell line enhanced" "Detected in many" "HL-60: 4442.1;NB-4: 2549.7;THP-1: 4346.8;TIME: 2609.1;U-937: 3546.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000759 Enhanced Supported "Golgi apparatus" "Secreted to blood" NA NA 100000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" "HPA000759: AB_1079675" "unprognostic (3.61e-2)" "unprognostic (1.62e-2)" "unprognostic (2.78e-2)" "unprognostic (1.28e-1)" "unprognostic (1.37e-1)" "unprognostic (4.50e-2)" "unprognostic (1.30e-1)" "unprognostic (1.70e-2)" "unprognostic (1.63e-1)" "unprognostic (8.22e-2)" "unprognostic (5.80e-2)" "unprognostic (9.82e-2)" "prognostic unfavorable (3.18e-5)" "unprognostic (1.65e-1)" "unprognostic (2.32e-2)" "unprognostic (4.07e-2)" "unprognostic (4.08e-2)" 404.6 114.9 48.8 799.8 50.5 8096.7 136.4 55.5 99.6 93.2 70.1 101.8 77.9 63.5 25.9 91.0 96.8 316.4 111.9 48.2 67.8 98.3 239.4 347.3 437.2 82.4 59.3 30.7 68.4 131.6 62.1 355.6 67.8 58.9 118.9 15.5 40.1 57.4 37.5 18.9 111.4 219.4 65.5 362.8 95.0 18.3 64.7 228.9 72.7 117.1 314.6 508.3 46.1 71.0 5.3 43.0 0.2 0.4 768.1 749.7 1.2 94.9 63.9 235.1 283.5 0.1 18.2 9.1 117.4 4.1 134.4 1.1 0.0 20.6 799.9 535.7 0.4 87.1 29.8 0.3 312.7 4442.1 914.9 306.8 1.1 641.5 39.2 223.8 1227.8 13.3 82.5 419.9 1239.9 0.2 18.7 2549.7 0.7 0.1 84.6 2.4 2.3 446.7 0.6 6.0 0.3 0.8 2.3 0.6 16.0 0.0 2.2 4346.8 2609.1 187.9 12.9 3.8 20.1 486.4 508.4 57.3 112.2 3546.9 1.2 2349.8 1105.3 2730.6 474.9 774.6 313.4 73.5 228.5 362.8 583.0 39.0 125.5 268.4 5714.1 962.8 693.6 631.9 392.6 1590.5 48.8 50.5 55.5 99.6 48.2 67.8 82.4 59.3 67.8 65.5 64.7 71.0 1081.4 112.2 198.1 0.7 592.0 175.9 12.5 38.3 8.6 1.1 16.0 28.2 21.2 21.5 57.5 33.1 0.0 10.2 2922.2 2.9 0.0 4.2 4.1 4.6 15.0 566.8 1.8 277.8 0.2 9.8 10.2 87.9 70.3 6.6 2343.1 0.4 636.1 22.1 847.1 0.0 0.5 1.7 0.0 1789.9 6618.2 8.4 7.5 3639.1 556.7 80.6 3188.2 1.4 1292.5 0.0 0.2 1.3 1.2 18.0 1740.9 12.2 0.3 4.7 45.6 5.0 72.3 22.8 97.5 0.9 2.2 8.7 141.8 14.2 2235.9 1.2 5.5 18.1 STX11 ENSG00000135604 "Syntaxin 11" O75558 6 144150517-144191939 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Familial hemophagocytic lymphohistiocytosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 25.1;bone marrow: 56.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 85.0;granulocytes: 90.3;Langerhans cells: 271.6;Macrophages: 158.0;monocytes: 85.5;Suprabasal keratinocytes: 154.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 7 "basophil: 22.6;classical monocyte: 68.4;eosinophil: 43.5;intermediate monocyte: 81.1;myeloid DC: 25.4;neutrophil: 81.7;non-classical monocyte: 87.0" "Group enriched" "Detected in all" 8 "dendritic cells: 25.4;granulocytes: 81.7;monocytes: 87.0" "Cell line enhanced" "Detected in some" "HDLM-2: 17.2;Karpas-707: 10.1;RH-30: 6.9;TIME: 8.3;U-266/70: 11.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA007992 Approved NA NA 1100000 "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA007992: AB_1857620" "unprognostic (1.30e-3)" "unprognostic (1.19e-1)" "unprognostic (1.68e-1)" "unprognostic (2.62e-2)" "unprognostic (3.73e-2)" "unprognostic (8.96e-2)" "unprognostic (3.04e-2)" "unprognostic (1.74e-1)" "unprognostic (2.85e-1)" "unprognostic (1.03e-2)" "unprognostic (8.65e-2)" "unprognostic (1.36e-1)" "unprognostic (4.47e-3)" "unprognostic (7.07e-2)" "unprognostic (3.91e-2)" "unprognostic (8.50e-3)" "unprognostic (1.07e-1)" 25.1 4.4 0.6 5.8 0.6 56.5 14.5 0.6 1.1 1.9 0.7 2.8 1.0 1.4 0.3 5.1 2.6 2.1 7.3 0.7 0.8 3.6 3.1 21.3 5.5 1.0 0.7 0.9 1.1 0.6 2.1 2.4 0.9 1.3 0.9 0.2 2.1 0.3 2.5 8.2 3.3 1.9 0.8 14.1 2.0 1.1 0.9 1.8 7.5 0.9 3.5 4.0 3.2 1.1 0.4 0.1 0.1 3.9 0.2 0.3 0.6 0.4 0.3 0.4 0.7 0.1 0.4 0.1 0.4 0.6 0.7 0.6 0.0 0.1 0.2 17.2 0.6 3.0 0.6 0.1 1.0 0.9 0.5 0.0 0.0 0.2 0.1 0.2 4.3 0.8 0.1 10.1 0.5 0.2 0.4 0.9 0.0 0.0 0.3 0.1 6.9 0.6 0.0 1.9 0.2 0.1 1.2 0.1 1.7 0.3 0.1 3.8 8.3 0.2 1.0 0.4 0.3 11.6 4.6 0.1 0.2 2.1 0.4 22.6 68.4 43.5 6.0 81.1 3.8 1.4 2.7 5.1 25.4 2.4 1.0 3.0 81.7 3.2 87.0 2.7 8.3 43.9 0.6 0.6 0.6 1.1 0.7 0.8 1.0 0.7 0.9 0.8 0.9 1.1 41.9 54.5 10.7 0.0 16.6 85.0 11.3 6.3 3.4 0.0 11.1 4.6 4.5 4.3 6.6 1.8 0.0 0.9 38.1 0.1 0.0 6.4 0.4 3.7 0.7 23.7 3.5 6.1 0.1 2.6 5.7 11.2 0.5 5.0 90.3 0.2 8.2 1.4 30.1 0.0 0.1 0.4 2.0 73.7 271.6 1.2 0.6 158.0 44.4 2.8 85.5 0.0 21.6 0.0 0.1 6.1 3.3 0.0 63.1 14.4 0.0 0.1 10.7 0.1 0.0 46.6 9.7 3.0 3.8 11.2 154.6 28.0 36.6 3.2 0.6 33.3 TLR2 "CD282, TIL4" ENSG00000137462 "Toll like receptor 2" O60603 4 153684070-153706260 "CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 69.9;lymphoid tissue: 51.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 77.3;Kupffer cells: 117.2;Langerhans cells: 35.7;Macrophages: 101.8;Microglial cells: 33.7;monocytes: 68.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 199.6;intermediate monocyte: 178.9;myeloid DC: 121.3;neutrophil: 457.8;non-classical monocyte: 121.5" "Group enriched" "Detected in all" 49 "dendritic cells: 121.3;granulocytes: 457.8;monocytes: 199.6" "Cell line enhanced" "Detected in some" "HL-60: 11.6;HSkMC: 12.5;hTCEpi: 12.7;NB-4: 11.4;RPTEC TERT1: 13.3;RT4: 16.3;THP-1: 62.0;U-937: 11.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA060231, HPA071546" Supported Nucleoplasm,Mitochondria No NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Mitochondria" "HPA060231: , HPA071546: " "unprognostic (4.15e-1)" "unprognostic (3.29e-2)" "unprognostic (5.32e-2)" "unprognostic (1.52e-2)" "unprognostic (3.46e-2)" "unprognostic (4.88e-2)" "unprognostic (1.39e-2)" "unprognostic (4.24e-2)" "unprognostic (2.48e-1)" "unprognostic (2.02e-2)" "unprognostic (2.04e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.11e-4)" "unprognostic (7.87e-2)" "unprognostic (3.80e-3)" "unprognostic (1.42e-1)" "unprognostic (5.93e-3)" 26.8 11.8 4.3 51.7 4.4 69.9 12.5 4.6 7.5 7.9 7.6 4.6 3.9 3.3 11.8 5.4 8.2 16.3 6.1 4.0 5.3 5.1 11.3 39.9 8.8 9.5 5.9 2.5 8.8 3.4 4.0 11.4 7.9 4.7 3.3 1.5 17.2 12.3 1.7 3.5 4.9 11.7 7.1 35.9 5.2 1.9 7.4 3.6 3.4 3.7 15.4 23.6 4.0 10.1 7.1 0.1 0.3 0.0 1.0 2.9 0.0 0.0 0.5 0.5 0.8 3.3 0.4 0.0 0.8 0.0 0.0 6.4 0.6 0.4 0.3 0.1 0.1 0.2 0.0 0.8 0.1 11.6 0.9 12.5 12.7 0.0 0.1 0.8 0.0 0.0 0.0 0.1 0.1 0.1 0.0 11.4 0.7 0.0 2.7 0.3 0.0 0.0 13.3 16.3 0.0 0.3 0.7 0.1 3.3 0.4 0.0 62.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.7 11.3 1.7 48.4 199.6 1.8 0.3 178.9 0.5 0.4 1.1 0.3 121.3 1.2 1.3 0.2 457.8 5.3 121.5 1.1 0.2 76.2 4.3 4.4 4.6 7.5 4.0 5.3 9.5 5.9 7.9 7.1 7.4 10.1 1.7 6.4 77.3 0.7 1.1 1.1 1.2 18.4 1.2 0.0 9.7 2.2 1.3 2.8 19.5 3.7 0.0 0.2 0.6 0.2 0.0 5.0 0.3 1.6 0.5 2.6 0.0 3.6 0.1 3.8 0.2 1.9 2.6 4.9 3.8 0.5 1.4 1.8 17.4 0.0 0.5 0.3 0.0 117.2 35.7 1.3 0.6 101.8 1.8 33.7 68.4 0.4 1.0 1.0 0.1 3.1 0.0 0.4 1.4 3.4 1.5 1.0 7.5 0.3 13.1 0.6 5.1 0.2 1.0 1.9 1.1 0.1 2.3 0.5 0.5 2.0 VNN2 "FOAP-4, GPI-80" ENSG00000112303 "Vanin 2" O95498 6 132743870-132763459 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.6;lymphoid tissue: 56.6" "Cell type enhanced" "Detected in many" "Ductal cells: 63.6;Ionocytes: 22.4;Macrophages: 41.1;monocytes: 57.5;Respiratory ciliated cells: 25.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 7 "neutrophil: 477.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 477.4" "Cell line enriched" "Detected in some" 7 "Daudi: 59.7" "Low region specificity" "Detected in some" NA NA 240000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (2.13e-1)" "unprognostic (1.15e-1)" "unprognostic (9.60e-3)" "unprognostic (5.71e-2)" "unprognostic (2.14e-1)" "unprognostic (5.61e-3)" "unprognostic (1.98e-3)" "unprognostic (4.38e-1)" "unprognostic (3.07e-1)" "unprognostic (3.46e-1)" "unprognostic (2.84e-1)" "unprognostic (8.30e-2)" "prognostic unfavorable (2.72e-7)" "unprognostic (1.62e-1)" "unprognostic (8.17e-2)" "unprognostic (2.01e-1)" "unprognostic (5.45e-2)" 21.7 2.7 0.6 23.9 0.9 31.6 1.3 0.7 2.8 4.3 1.4 3.8 2.4 1.3 0.4 4.1 5.3 22.5 2.3 0.5 0.7 2.4 10.1 22.5 39.0 1.5 1.0 1.5 4.3 0.7 0.9 20.7 1.7 1.8 3.0 0.1 1.5 0.9 0.6 0.3 4.6 6.3 0.8 56.6 7.3 0.6 1.0 11.7 1.2 7.9 42.0 17.8 1.2 1.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 59.7 1.1 0.0 1.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.9 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 1.1 1.4 0.0 0.0 11.6 65.2 0.3 24.6 14.5 10.3 40.3 8.4 29.0 14.1 32.2 27.0 39.4 477.4 36.1 9.9 2.6 6.1 40.4 0.6 0.9 0.7 2.8 0.5 0.7 1.5 1.0 1.7 0.8 1.0 1.0 0.2 0.0 6.7 0.0 11.0 0.0 0.5 4.3 0.0 0.0 0.2 0.0 1.5 7.2 11.8 0.0 0.0 0.8 10.9 0.1 0.0 63.6 0.0 0.3 0.0 1.4 0.0 1.3 0.2 0.4 0.2 1.9 13.3 0.2 5.1 0.1 3.3 1.0 13.9 0.0 0.0 0.0 22.4 18.6 1.0 0.0 0.0 41.1 0.0 1.9 57.5 0.3 20.6 0.0 0.1 3.6 0.0 0.0 2.7 8.0 0.0 0.6 25.4 0.1 6.6 2.5 1.2 0.1 0.0 0.1 0.0 1.4 10.9 6.5 0.2 14.5