Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABAT "GABA-T, GABAT" ENSG00000183044 "4-aminobutyrate aminotransferase" P80404 16 8674596-8784575 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Neurotransmitter degradation" "Aminotransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 137.9;kidney: 133.3;liver: 345.6;pancreas: 138.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 268.2;Inhibitory neurons: 95.0;Oligodendrocyte precursor cells: 76.9;Proximal tubular cells: 94.9" "Cancer enhanced" "Detected in all" "glioma: 27.3;liver cancer: 26.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 127.5;MCF7: 81.9;RH-30: 67.4;T-47d: 42.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041528, HPA041690" Enhanced Supported Supported Mitochondria No No 2100000 "Cluster 14: Monocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA041528: AB_10795690, HPA041690: AB_10794674" "unprognostic (1.77e-2)" "unprognostic (3.27e-1)" "unprognostic (1.00e-1)" "unprognostic (2.71e-1)" "unprognostic (2.90e-1)" "unprognostic (2.05e-1)" "prognostic favorable (5.36e-5)" "prognostic favorable (5.93e-4)" "unprognostic (1.71e-1)" "unprognostic (1.30e-1)" "unprognostic (1.56e-2)" "unprognostic (1.04e-1)" "prognostic favorable (5.44e-8)" "unprognostic (2.10e-1)" "unprognostic (2.48e-2)" "unprognostic (3.80e-1)" "unprognostic (1.50e-2)" 3.3 27.7 94.6 4.7 105.4 2.2 5.1 85.2 103.4 3.8 70.7 7.6 43.6 3.8 9.6 7.7 6.2 4.4 14.1 90.2 120.7 133.3 345.6 4.5 5.0 90.8 107.4 10.5 138.3 8.2 55.8 3.4 137.6 21.7 7.8 29.6 6.5 3.5 1.6 2.7 20.1 2.7 88.1 4.1 7.4 13.4 137.9 4.2 29.3 1.4 5.9 9.9 4.1 70.9 0.7 0.2 32.1 18.7 5.0 1.7 2.0 4.2 2.2 1.8 0.7 12.7 0.9 4.0 1.4 2.3 1.2 8.3 2.1 7.7 2.4 2.3 2.1 5.5 0.1 127.5 8.1 1.3 8.3 6.5 3.4 3.2 1.4 0.9 0.6 10.7 1.1 2.6 0.6 81.9 2.1 0.6 2.8 23.2 0.3 9.7 67.4 1.8 1.2 20.9 5.1 15.7 1.9 1.0 0.2 6.2 42.6 3.4 0.6 0.8 5.7 2.7 0.1 3.0 0.3 0.8 0.8 5.7 4.2 0.7 1.9 2.7 1.5 2.2 0.7 0.6 1.0 1.1 1.2 1.2 0.7 1.1 6.1 1.2 4.2 0.2 1.1 1.2 94.6 105.4 85.2 103.4 90.2 120.7 90.8 107.4 137.6 88.1 137.9 70.9 1.7 0.0 6.9 39.5 6.1 1.5 4.0 3.3 2.2 27.3 9.1 5.0 10.8 20.0 5.8 1.8 4.2 1.4 5.3 8.9 23.5 1.6 13.0 12.9 6.2 2.4 15.6 13.9 41.8 6.2 1.5 3.2 5.6 12.9 1.3 59.5 7.1 268.2 5.2 35.3 95.0 3.9 2.0 15.7 7.4 8.7 3.7 8.2 1.8 19.7 6.5 48.6 9.2 76.9 17.7 6.8 6.1 4.5 1.0 7.4 15.7 94.9 3.6 5.8 0.0 4.3 3.8 3.7 0.9 9.5 0.6 1.4 6.3 2.3 6.9 5.0 ABCA6 EST155051 ENSG00000154262 "ATP binding cassette subfamily A member 6" Q8N139 17 69078702-69141895 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 77.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 62.5;Fibroblasts: 117.6;Hepatocytes: 110.3;Inhibitory neurons: 77.8;Leydig cells: 51.3;Microglial cells: 93.7;Theca cells: 45.4" "Cancer enriched" "Detected in some" 7 "liver cancer: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 39.9;ASC TERT1: 56.0;HSkMC: 25.3;HUVEC TERT2: 54.8;RT4: 14.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA064878, HPA067180" Enhanced Nucleoplasm NA NA "Cluster 85: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA064878: AB_2685380, HPA067180: AB_2685797" "unprognostic (7.76e-2)" "unprognostic (6.80e-2)" "unprognostic (2.12e-1)" "unprognostic (8.01e-2)" "unprognostic (8.47e-2)" "unprognostic (9.82e-3)" "prognostic favorable (3.29e-4)" "unprognostic (1.35e-1)" "unprognostic (6.60e-2)" "unprognostic (3.00e-2)" "unprognostic (2.94e-1)" "unprognostic (1.02e-1)" "unprognostic (7.96e-4)" "unprognostic (1.61e-4)" "unprognostic (2.10e-2)" "unprognostic (3.03e-2)" "unprognostic (1.69e-1)" 23.3 5.5 1.3 2.6 5.5 0.0 15.9 5.1 3.2 10.5 3.1 8.0 2.2 5.9 2.8 5.9 11.3 10.1 17.5 1.1 4.1 3.6 77.9 10.9 5.0 14.3 3.0 29.8 2.3 1.3 2.1 2.1 9.4 2.9 4.4 0.8 9.0 2.0 5.4 6.6 5.5 3.7 7.1 1.5 5.7 1.8 3.4 1.4 8.6 11.7 3.2 14.2 8.9 21.3 0.0 0.0 0.0 0.0 39.9 56.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 25.3 0.1 3.2 0.9 1.5 54.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 2.5 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 5.5 5.1 3.2 1.1 4.1 14.3 3.0 9.4 7.1 3.4 21.3 12.5 0.0 0.0 2.9 2.0 3.1 1.5 0.4 4.0 11.6 1.8 2.2 6.0 4.3 0.9 3.7 6.2 0.0 1.7 1.8 0.0 0.5 3.3 0.7 5.1 3.2 2.4 2.7 62.5 0.2 0.0 117.6 2.0 2.5 0.0 4.0 3.3 110.3 1.6 0.0 77.8 0.7 0.0 2.5 42.1 2.7 51.3 20.3 5.4 93.7 0.7 3.2 0.0 4.5 33.4 0.4 1.1 12.0 1.2 0.1 0.5 0.9 0.7 13.3 0.0 20.0 14.3 2.0 0.9 1.4 2.8 0.0 1.2 45.4 0.3 0.5 ABHD1 "FLJ36128, LABH1" ENSG00000143994 "Abhydrolase domain containing 1" Q96SE0 2 27123789-27130812 "Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 21.6" "Group enriched" "Detected in many" 9 "Early spermatids: 295.1;Late spermatids: 1030.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.5;T-47d: 3.3;U-266/70: 3.0;U-266/84: 2.8" "Low region specificity" "Detected in all" HPA044390 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA044390: AB_10959380" "unprognostic (1.20e-3)" "unprognostic (6.07e-3)" "unprognostic (7.71e-4)" "unprognostic (1.63e-2)" "unprognostic (6.68e-2)" "unprognostic (2.70e-2)" "unprognostic (1.13e-1)" "unprognostic (1.06e-3)" "unprognostic (2.75e-1)" "unprognostic (1.76e-1)" "unprognostic (9.09e-4)" "unprognostic (9.76e-2)" "unprognostic (1.70e-2)" "unprognostic (6.88e-2)" "unprognostic (4.06e-2)" "unprognostic (3.09e-2)" "unprognostic (7.97e-2)" 1.2 0.6 0.8 0.1 0.7 0.0 0.5 1.5 1.1 0.1 0.3 0.1 0.0 0.3 0.4 0.1 0.2 0.2 0.5 0.7 0.8 0.3 3.3 0.1 0.2 0.9 0.7 0.4 0.1 0.4 0.2 0.0 0.9 0.7 0.0 0.4 1.5 0.2 1.9 0.0 0.1 0.3 0.9 0.1 0.2 21.6 0.9 0.0 0.4 1.7 0.1 0.0 0.0 0.9 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.5 0.0 0.0 1.5 0.1 0.0 0.0 0.3 0.0 0.3 0.1 0.0 3.3 0.2 0.0 0.0 0.0 0.0 0.2 3.0 2.8 0.0 0.1 0.1 0.1 0.0 0.2 0.8 0.6 0.0 0.2 0.5 0.3 0.3 0.0 0.3 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.8 0.7 1.5 1.1 0.7 0.8 0.9 0.7 0.9 0.9 0.9 0.9 0.8 0.0 0.0 4.9 1.0 0.0 3.3 0.0 2.8 5.1 1.9 2.8 3.1 1.5 0.0 0.0 8.4 0.2 0.9 0.2 0.0 0.3 295.1 0.4 0.6 1.9 0.0 3.2 0.6 0.2 0.0 1.3 0.0 0.5 1.3 1.6 2.5 3.9 0.1 0.0 0.8 0.2 0.0 0.3 0.3 1030.5 6.5 1.2 0.0 1.9 0.5 8.1 3.1 2.0 2.2 0.0 0.0 5.7 0.5 3.6 0.2 3.0 0.7 4.9 0.0 2.4 1.2 70.5 3.9 0.3 0.3 0.0 1.8 0.3 0.2 2.2 ACAT1 "ACAT, THIL" ENSG00000075239 "Acetyl-CoA acetyltransferase 1" P24752 11 108116695-108147603 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 622.7;liver: 969.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 508.4;Distal tubular cells: 698.5;Hepatocytes: 663.4;Proximal tubular cells: 1484.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 420.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004428, HPA007569" Enhanced Enhanced Mitochondria NA NA 1400000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA004428: AB_1078088, HPA007569: AB_1844482" "unprognostic (3.70e-3)" "unprognostic (2.23e-2)" "unprognostic (7.84e-3)" "unprognostic (4.65e-2)" "unprognostic (3.05e-2)" "unprognostic (1.12e-1)" "prognostic favorable (1.43e-5)" "unprognostic (3.59e-3)" "unprognostic (1.26e-1)" "unprognostic (5.20e-2)" "unprognostic (2.64e-2)" "unprognostic (1.13e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.96e-1)" "unprognostic (1.68e-1)" "unprognostic (8.06e-2)" "unprognostic (6.62e-3)" 135.4 151.3 45.2 24.3 45.3 38.4 56.9 47.1 60.1 41.0 91.8 96.3 103.9 44.0 34.1 45.0 39.1 25.6 289.4 42.7 46.8 622.7 969.5 43.7 28.2 44.8 45.2 64.7 110.6 95.9 30.9 24.7 45.2 45.6 85.6 26.2 104.1 60.2 461.1 45.3 53.2 57.1 46.7 29.3 81.9 66.3 45.6 19.1 65.5 410.8 29.7 44.1 34.6 47.7 76.9 57.7 48.2 139.3 155.9 138.7 25.1 71.7 78.8 77.7 91.7 168.1 77.3 41.3 116.8 83.6 119.7 78.1 142.3 70.3 83.3 84.9 114.6 117.4 64.6 163.9 107.6 112.9 64.9 124.6 77.1 69.2 127.4 91.5 85.0 92.3 172.1 61.8 128.6 45.8 57.4 122.4 48.2 103.1 135.0 88.1 96.9 420.4 114.7 50.4 75.7 88.1 111.6 152.7 83.0 37.0 132.2 97.6 87.4 83.2 44.5 73.5 88.8 18.9 57.8 77.7 37.6 233.1 59.6 1.4 17.1 4.7 25.3 25.5 29.9 29.2 28.8 30.0 33.5 13.8 25.5 22.4 1.8 13.4 27.8 11.3 35.7 23.4 45.2 45.3 47.1 60.1 42.7 46.8 44.8 45.2 45.2 46.7 45.6 47.7 50.5 54.5 91.8 17.9 37.2 43.1 52.2 48.9 23.9 30.1 34.6 29.6 508.4 78.6 33.5 104.8 27.1 39.9 29.2 125.0 698.5 43.1 345.7 62.2 42.1 62.5 30.0 74.7 35.1 60.5 41.5 57.1 29.0 25.7 27.8 48.6 99.2 663.4 97.9 38.7 37.8 38.5 97.6 73.6 27.8 65.3 66.5 39.1 58.7 30.0 50.1 39.1 25.7 22.6 26.5 33.8 93.8 82.4 52.7 27.8 51.4 1484.0 101.8 28.8 65.7 54.2 69.2 172.7 27.2 39.2 48.4 25.2 38.1 61.6 84.5 24.4 ACBD5 "DKFZp434A2417, KIAA1996" ENSG00000107897 "Acyl-CoA binding domain containing 5" Q5T8D3 10 27168135-27243046 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autophagy, Transport" Leukodystrophy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011861, HPA012145" Enhanced Enhanced Peroxisomes NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 45: Enterocytes - Digestion" Peroxisomes "HPA011861: AB_1844493, HPA012145: AB_1844494" "prognostic unfavorable (3.33e-4)" "unprognostic (4.93e-1)" "unprognostic (3.68e-1)" "unprognostic (1.34e-1)" "unprognostic (6.21e-2)" "unprognostic (5.98e-3)" "unprognostic (9.87e-2)" "unprognostic (3.42e-2)" "unprognostic (2.69e-1)" "unprognostic (3.66e-1)" "unprognostic (1.11e-1)" "unprognostic (4.46e-2)" "prognostic favorable (4.68e-5)" "unprognostic (7.91e-3)" "unprognostic (1.71e-1)" "unprognostic (3.63e-2)" "unprognostic (3.37e-3)" 14.6 25.1 31.0 13.5 37.0 18.2 12.3 36.2 37.1 13.2 24.2 20.3 39.8 9.4 9.7 12.0 12.0 15.4 40.4 27.6 33.1 37.3 73.8 14.7 14.7 37.2 34.0 9.9 11.1 31.2 6.4 13.4 38.1 15.2 20.9 36.2 10.3 11.4 31.0 17.3 39.2 8.8 36.7 14.7 21.0 19.3 36.1 12.2 27.8 36.6 12.7 13.5 7.5 38.8 25.8 76.5 17.1 18.0 19.1 17.3 20.1 32.3 12.1 28.1 33.5 19.4 39.9 10.7 27.0 22.4 23.4 21.1 23.2 16.3 23.0 26.2 23.9 16.5 23.1 15.2 20.6 11.0 20.9 16.7 17.7 23.5 12.8 24.9 20.5 16.7 13.6 19.5 35.7 20.0 21.1 9.4 13.1 35.2 10.0 17.4 42.5 20.2 44.1 22.4 21.3 45.5 35.4 38.3 17.9 18.9 18.8 11.5 30.4 27.2 15.2 43.7 25.9 19.4 28.1 20.7 27.4 24.6 12.0 12.5 13.0 10.2 15.3 12.7 15.2 6.4 7.5 12.4 13.0 7.0 5.0 11.0 11.1 10.3 15.1 8.5 7.4 8.0 31.0 37.0 36.2 37.1 27.6 33.1 37.2 34.0 38.1 36.7 36.1 38.8 23.3 25.6 29.9 17.9 16.0 9.7 4.1 14.5 7.4 30.8 14.5 10.8 83.0 15.7 25.2 31.3 25.0 9.6 27.4 22.4 33.2 22.1 43.1 33.7 20.2 18.7 10.2 8.6 20.6 16.2 12.6 16.4 19.4 41.1 12.6 11.5 12.8 56.9 19.0 23.5 26.9 30.4 10.2 25.5 12.5 16.9 16.4 22.4 21.4 15.9 22.4 47.7 29.9 17.6 24.8 17.8 26.1 16.6 14.2 11.7 64.4 48.2 32.7 47.2 19.7 20.9 16.1 41.0 8.3 16.5 15.5 10.4 22.3 27.1 26.5 9.2 ACE2 ENSG00000130234 "Angiotensin I converting enzyme 2" Q9BYF1 X 15494566-15607236 "Enzymes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Host-virus interaction" "Carboxypeptidase, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 65.5;intestine: 242.2;kidney: 87.6" "Cell type enriched" "Detected in many" 5 "Proximal enterocytes: 294.8" "Group enriched" "Detected in many" 4 "colorectal cancer: 13.9;renal cancer: 26.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 1.2;NTERA-2: 1.2;SuSa: 1.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA000288, CAB026174, CAB026213, CAB080024, CAB080025, CAB080027, CAB080028" Enhanced "Secreted to blood" NA NA 400000 "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 45: Enterocytes - Digestion" "CAB026174: , CAB026213: , CAB080024: AB_10864415, CAB080025: AB_2809589, CAB080027: AB_2665870, CAB080028: AB_2665871, HPA000288: AB_1078160" "unprognostic (1.40e-1)" "unprognostic (7.26e-2)" "unprognostic (2.76e-2)" "unprognostic (5.71e-2)" "unprognostic (2.51e-1)" "unprognostic (5.26e-2)" "prognostic favorable (4.21e-4)" "unprognostic (2.34e-2)" "unprognostic (6.74e-3)" "unprognostic (2.54e-3)" "unprognostic (1.00e-1)" "unprognostic (1.74e-1)" "prognostic favorable (2.12e-5)" "unprognostic (1.94e-1)" "unprognostic (9.62e-2)" "unprognostic (2.11e-1)" "unprognostic (7.10e-2)" 8.9 0.5 0.1 1.4 0.1 0.6 4.3 0.4 0.3 0.6 1.9 9.9 183.3 0.5 0.5 1.8 1.5 65.5 42.7 0.2 0.2 87.6 5.7 0.8 0.4 0.2 0.2 1.8 2.5 1.5 0.1 1.2 0.2 0.4 5.9 0.3 1.4 4.1 0.7 0.3 242.2 0.5 0.1 0.1 2.6 49.7 0.2 0.5 4.5 0.5 0.2 0.8 1.2 0.2 0.0 0.0 0.3 0.0 0.2 0.0 0.8 0.1 0.0 0.2 0.2 0.2 0.3 0.4 0.3 0.0 0.3 0.7 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.5 1.2 1.2 0.0 0.0 0.3 0.2 0.5 0.2 0.4 0.2 0.9 0.0 0.4 0.0 1.9 0.4 0.4 0.1 0.0 0.0 0.3 0.4 0.1 0.5 0.5 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.3 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.4 0.0 0.5 1.3 1.4 0.1 0.5 5.0 0.0 0.0 1.6 0.0 11.2 55.8 2.6 0.0 0.0 4.2 0.1 22.9 3.9 1.2 0.5 1.1 0.3 1.0 7.2 0.0 0.8 0.8 0.3 4.6 0.0 0.6 0.0 3.9 0.0 0.9 0.8 0.0 0.8 8.2 0.0 0.0 0.0 1.4 8.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.9 5.1 6.0 0.0 1.0 294.8 48.8 2.0 0.0 19.7 0.0 8.9 1.1 1.0 0.0 0.1 12.7 0.3 0.1 10.6 2.2 ACMSD ENSG00000153086 "Aminocarboxymuconate semialdehyde decarboxylase" Q8TDX5 2 134838616-134902034 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "kidney: 141.1;liver: 162.5" "Group enriched" "Detected in some" 4 "Hepatocytes: 120.2;Proximal tubular cells: 408.1" "Group enriched" "Detected in some" 23 "liver cancer: 21.2;renal cancer: 19.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 21 "RPTEC TERT1: 26.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA010533, HPA011179" Enhanced Approved Cytosol NA NA 12000 "Cluster 37: B-cells - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA010533: AB_1844517, HPA011179: AB_1844516" "unprognostic (1.06e-2)" "unprognostic (5.30e-2)" "unprognostic (1.40e-1)" "unprognostic (7.50e-2)" "unprognostic (3.79e-2)" "unprognostic (1.36e-2)" "unprognostic (4.40e-3)" "unprognostic (1.15e-1)" "unprognostic (5.35e-4)" "unprognostic (7.60e-2)" "unprognostic (5.17e-2)" "unprognostic (2.44e-3)" "prognostic favorable (2.39e-4)" "unprognostic (1.26e-1)" "unprognostic (1.70e-1)" "unprognostic (2.93e-2)" "unprognostic (2.65e-5)" 0.0 0.2 0.1 0.1 0.0 0.2 0.1 0.9 0.3 0.0 0.0 0.1 0.9 0.1 0.0 0.0 0.0 7.1 0.2 0.0 0.3 141.1 162.5 0.1 0.3 0.8 0.2 0.7 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.4 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.6 0.4 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.4 0.1 1.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.7 0.4 0.1 0.8 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.4 0.6 0.0 0.0 0.3 0.8 0.3 1.2 0.2 0.5 0.1 0.6 0.3 26.7 0.4 1.0 0.3 0.1 0.3 0.4 0.8 0.2 0.7 1.0 0.0 0.4 0.2 0.8 0.2 0.1 0.5 0.2 0.3 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.9 0.3 0.0 0.3 0.8 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.2 50.1 0.0 9.2 0.0 0.0 0.0 0.0 54.8 0.2 0.0 0.0 0.1 0.0 0.0 2.7 8.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.9 120.2 0.0 0.0 7.3 0.0 0.0 1.9 0.0 0.0 0.0 2.8 0.0 1.0 0.0 0.0 0.0 2.5 1.9 0.1 0.0 0.0 0.0 0.0 0.0 408.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 ACO1 "IREB1, IREBP, IRP1" ENSG00000122729 "Aconitase 1" P21399 9 32384603-32454769 "Cancer-related genes, Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Lyase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 134.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 194.4;Proximal tubular cells: 183.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 194.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019371, HPA024157" Enhanced Supported Mitochondria,Cytosol NA NA 10000000 "Cluster 38: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Mitochondria, Cytosol" "HPA019371: AB_1844519, HPA024157: AB_1844520" "unprognostic (2.11e-1)" "unprognostic (5.61e-2)" "unprognostic (8.38e-2)" "unprognostic (9.12e-2)" "unprognostic (2.63e-1)" "unprognostic (3.12e-2)" "unprognostic (4.25e-3)" "unprognostic (2.61e-2)" "unprognostic (1.37e-1)" "unprognostic (1.19e-1)" "unprognostic (2.55e-1)" "unprognostic (3.08e-1)" "prognostic favorable (5.73e-5)" "unprognostic (2.54e-1)" "unprognostic (6.58e-2)" "unprognostic (1.65e-1)" "unprognostic (3.23e-2)" 96.6 50.5 15.2 16.1 15.4 3.5 50.1 14.6 15.3 19.8 19.1 23.7 48.6 19.2 30.2 15.4 14.6 15.6 36.3 14.0 16.2 89.2 134.5 20.3 8.8 15.8 15.8 17.4 37.6 22.8 13.1 16.1 14.9 21.9 20.6 12.9 16.6 19.1 25.1 12.0 35.8 22.9 15.3 9.3 28.7 17.6 16.9 13.6 34.5 37.8 7.1 24.4 13.7 14.1 37.5 33.7 25.7 40.7 194.5 104.8 11.6 69.3 169.1 31.2 24.5 36.0 11.4 7.4 21.6 73.1 84.9 5.1 51.3 66.3 62.3 23.8 13.8 54.7 33.4 39.3 97.4 5.1 21.2 91.7 20.1 80.4 56.1 95.6 81.7 28.4 20.0 15.7 89.9 9.9 29.5 26.4 26.9 23.3 35.5 22.8 38.0 7.8 118.9 34.1 3.3 10.5 71.9 2.8 7.6 27.1 16.7 13.5 89.2 112.5 38.2 38.2 18.2 7.8 15.5 14.7 78.7 18.2 10.2 33.2 11.3 3.3 9.2 11.3 8.0 5.6 6.2 6.9 9.3 5.0 8.1 8.2 1.2 6.7 10.0 4.3 3.9 8.4 15.2 15.4 14.6 15.3 14.0 16.2 15.8 15.8 14.9 15.3 16.9 14.1 16.3 3.2 25.7 43.8 6.7 4.5 7.9 11.9 9.1 21.4 17.8 7.4 45.5 38.6 11.7 23.9 22.9 50.8 6.2 26.4 19.6 19.0 8.7 10.0 30.7 18.7 4.9 11.6 24.6 41.0 22.1 29.7 39.3 13.9 2.5 17.1 15.7 194.4 15.1 33.7 46.5 27.7 10.2 14.8 6.7 6.9 23.6 15.6 7.2 20.6 8.6 25.7 8.2 22.1 24.1 19.4 23.7 23.3 7.2 10.1 56.1 183.4 10.7 14.3 19.7 30.5 22.2 9.8 19.4 10.3 5.4 53.5 7.5 22.2 34.6 8.7 ACOT12 "Cach, STARD15, THEAL" ENSG00000172497 "Acyl-CoA thioesterase 12" Q8WYK0 5 81329996-81394179 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "liver: 100.7" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 36.2" "Cancer enriched" "Detected in single" 76 "liver cancer: 13.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA037723 Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 62: Liver - Hemostasis" "Cluster 2: Hepatocytes - Metabolism" Cytosol "Nucleoplasm, Cytokinetic bridge" "HPA037723: AB_10672606" "unprognostic (6.06e-2)" "unprognostic (1.39e-1)" "prognostic favorable (5.30e-4)" "unprognostic (7.68e-2)" "unprognostic (8.22e-2)" "unprognostic (5.68e-3)" "unprognostic (2.46e-1)" "unprognostic (6.86e-2)" "unprognostic (1.46e-2)" "unprognostic (3.07e-1)" "unprognostic (1.06e-1)" 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.5 2.7 100.7 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.0 0.5 0.3 0.5 0.3 0.3 0.6 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.8 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 8.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 36.2 0.5 0.0 1.2 0.0 0.0 1.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 3.4 4.2 0.0 0.0 0.0 0.4 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 ADAMTS5 "ADAMTS11, ADMP-2" ENSG00000154736 "ADAM metallopeptidase with thrombospondin type 1 motif 5" Q9UNA0 21 26917922-26967088 "Cancer-related genes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 26.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 38.2;Endometrial stromal cells: 72.1;Fibroblasts: 88.6;Leydig cells: 62.7;Skeletal myocytes: 110.2;Smooth muscle cells: 44.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 31.6;ASC TERT1: 13.9;fHDF/TERT166: 11.9;RH-30: 33.1;U-87 MG: 13.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "HPA005661, CAB025996, HPA030906, HPA030908" Approved Supported Nucleoplasm "Secreted to extracellular matrix" NA NA 28000 "Cluster 5: Breast - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "CAB025996: , HPA005661: AB_1078101, HPA030906: AB_2673654, HPA030908: AB_2673655" "unprognostic (1.97e-1)" "unprognostic (2.88e-3)" "unprognostic (2.69e-2)" "unprognostic (4.01e-2)" "unprognostic (4.67e-1)" "unprognostic (2.10e-2)" "unprognostic (4.38e-8)" "unprognostic (1.11e-3)" "unprognostic (7.66e-2)" "unprognostic (6.17e-2)" "unprognostic (8.13e-2)" "unprognostic (7.76e-2)" "prognostic unfavorable (2.46e-4)" "unprognostic (6.69e-3)" "unprognostic (3.01e-1)" "prognostic unfavorable (8.54e-4)" "unprognostic (1.15e-1)" 17.5 0.8 0.3 1.0 0.6 0.0 10.8 3.3 0.3 8.8 2.6 2.7 0.8 12.5 2.4 1.6 4.2 1.6 3.3 0.5 0.9 2.5 1.4 1.0 0.6 1.4 0.9 16.6 0.4 1.5 0.4 26.2 0.9 3.0 1.3 0.6 2.0 1.8 2.0 4.2 3.4 7.5 1.5 7.7 2.2 0.8 0.4 0.3 6.8 3.7 0.1 4.2 3.6 1.2 0.0 0.0 0.0 0.0 31.6 13.9 0.0 1.7 0.2 1.4 0.6 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 2.3 0.0 1.3 0.0 0.3 0.0 3.5 0.1 0.0 8.0 0.0 1.1 0.2 0.2 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 33.1 0.0 3.4 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 8.3 0.4 1.9 0.9 0.0 0.0 0.0 13.0 0.1 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 3.3 0.3 0.5 0.9 1.4 0.9 0.9 1.5 0.4 1.2 24.3 0.0 0.5 0.3 0.1 2.9 0.2 0.4 0.0 9.8 1.5 38.2 2.7 0.0 0.6 3.7 0.0 1.1 0.3 0.0 0.0 0.0 6.4 2.0 72.1 10.6 1.8 0.0 0.5 0.2 1.6 88.6 0.0 1.3 0.0 3.0 3.3 0.0 1.9 0.0 11.6 0.0 0.0 0.0 4.6 1.0 62.7 1.4 3.6 3.7 4.0 0.1 0.0 12.5 0.2 0.0 0.0 9.1 0.0 0.3 0.0 2.2 0.0 0.2 13.1 110.2 44.9 0.3 0.9 0.4 3.0 2.7 0.8 20.0 0.0 0.1 ADAMTSL1 "ADAMTSR1, C9orf94, FLJ35283" ENSG00000178031 "ADAMTS like 1" Q8N6G6 9 17906563-18910950 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 13.3" "Cell type enriched" "Detected in some" 6 "Excitatory neurons: 245.4" "Cancer enhanced" "Detected in many" "prostate cancer: 2.6" "Region enhanced" "Detected in many" "thalamus: 9.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 118.3;HSkMC: 61.2;hTEC/SVTERT24-B: 64.3;hTERT-RPE1: 55.8;LHCN-M2: 64.3;TIME: 207.9;U-138 MG: 96.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057437, HPA074973" Uncertain Approved Vesicles "Secreted in other tissues" NA NA 28000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA057437: AB_2683440, HPA074973: " "unprognostic (4.64e-2)" "unprognostic (2.41e-1)" "unprognostic (3.95e-2)" "unprognostic (7.21e-2)" "unprognostic (2.45e-3)" "unprognostic (1.89e-1)" "unprognostic (1.52e-2)" "unprognostic (7.77e-2)" "unprognostic (2.01e-4)" "unprognostic (3.66e-2)" "unprognostic (1.21e-1)" "unprognostic (6.41e-2)" "unprognostic (7.29e-3)" "unprognostic (2.58e-2)" "unprognostic (1.87e-1)" "unprognostic (6.59e-2)" "unprognostic (1.50e-2)" 3.9 5.5 1.0 1.9 0.9 0.0 2.4 1.7 1.1 3.8 0.0 3.0 1.8 13.3 1.1 5.4 4.0 4.9 1.0 3.6 1.8 2.1 0.9 1.2 0.8 2.1 3.3 1.5 1.4 0.2 1.8 0.6 0.5 8.1 2.9 0.4 1.3 1.6 0.4 0.9 1.8 11.2 1.4 0.7 5.1 1.0 9.6 0.5 0.9 0.8 0.9 2.6 2.0 1.0 6.4 0.5 1.2 0.0 17.5 118.3 0.0 3.6 16.3 14.8 33.3 0.0 0.1 0.1 0.1 44.1 5.5 0.0 6.6 1.1 41.7 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 61.2 0.0 64.3 0.2 55.8 27.1 0.0 0.1 0.3 64.3 0.0 0.2 0.1 5.6 0.0 0.3 0.0 10.1 0.2 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 207.9 96.9 2.5 2.6 15.8 0.0 0.0 0.0 31.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 1.7 1.1 3.6 1.8 2.1 3.3 0.5 1.4 9.6 1.0 1.6 0.0 0.0 5.2 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.4 1.4 0.0 0.6 0.0 0.0 0.0 0.0 3.1 0.0 0.1 7.2 0.3 1.1 8.9 0.0 0.0 245.4 0.0 0.0 15.1 0.5 0.5 0.0 0.1 1.1 0.0 0.1 0.0 39.5 0.4 0.0 0.0 0.8 2.9 5.0 0.1 0.0 1.9 0.0 0.0 0.0 9.0 5.7 0.0 0.4 1.2 0.0 0.6 0.2 0.4 0.0 0.0 0.0 0.1 1.2 2.9 1.6 0.1 0.1 0.1 0.0 0.1 1.7 0.1 ADAP2 CENTA2 ENSG00000184060 "ArfGAP with dual PH domains 2" Q9NPF8 17 30906344-30959322 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 86.2;Hofbauer cells: 195.8;Kupffer cells: 186.8;Macrophages: 97.2;monocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 22.4;intermediate monocyte: 34.3;myeloid DC: 12.6;non-classical monocyte: 43.5" "Group enriched" "Detected in many" 9 "dendritic cells: 12.6;monocytes: 43.5" "Cell line enhanced" "Detected in some" "EFO-21: 7.0;HAP1: 17.6;HEK 293: 11.0;RPMI-8226: 22.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (4.00e-2)" "unprognostic (1.68e-2)" "prognostic unfavorable (5.62e-4)" "unprognostic (2.25e-1)" "unprognostic (9.26e-2)" "prognostic favorable (3.97e-4)" "prognostic unfavorable (3.12e-4)" "unprognostic (2.38e-1)" "unprognostic (3.40e-1)" "unprognostic (1.54e-1)" "unprognostic (2.51e-1)" "unprognostic (9.49e-2)" "prognostic unfavorable (2.36e-6)" "unprognostic (1.42e-1)" "unprognostic (1.42e-2)" "unprognostic (1.17e-2)" "unprognostic (1.14e-2)" 11.3 8.9 6.6 15.3 7.6 3.9 4.6 6.7 8.5 2.9 9.1 6.5 5.7 3.2 2.9 3.1 3.3 9.2 4.4 6.2 8.0 5.1 11.0 9.8 9.8 12.1 9.6 1.9 3.1 9.1 1.9 19.7 10.4 2.4 8.0 1.3 3.1 3.1 1.8 6.7 5.6 9.8 8.6 22.5 4.3 2.0 14.7 4.6 3.2 6.4 6.7 9.0 2.2 12.9 0.1 1.7 0.2 0.4 0.4 0.5 4.5 0.1 0.0 0.3 0.1 0.7 0.7 1.0 7.0 0.1 0.2 0.1 17.6 0.2 0.3 0.4 11.0 0.0 1.0 2.0 2.9 0.4 1.9 1.1 4.4 0.9 0.6 0.2 0.0 0.0 0.2 1.8 0.6 3.6 0.1 0.3 0.1 0.4 0.1 0.3 0.0 22.9 2.4 2.3 0.3 0.1 0.3 0.2 0.1 1.5 3.8 2.9 0.0 0.4 1.1 0.8 0.1 0.8 0.5 1.0 0.4 0.4 0.0 0.2 22.4 0.0 0.0 34.3 0.0 3.0 0.1 0.1 12.6 2.1 0.1 0.1 1.7 0.0 43.5 0.4 0.4 6.6 6.6 7.6 6.7 8.5 6.2 8.0 12.1 9.6 10.4 8.6 14.7 12.9 5.4 3.2 5.2 2.6 8.6 2.0 0.5 0.5 2.2 0.8 0.7 2.4 1.5 1.5 0.9 0.0 2.1 23.5 0.2 3.1 0.0 0.3 0.6 1.7 0.6 7.8 0.0 0.4 1.1 1.4 86.2 1.9 0.0 1.2 3.8 0.4 4.6 1.6 195.8 0.0 1.4 0.6 0.0 186.8 13.1 0.5 0.9 97.2 0.0 40.3 88.2 0.6 2.1 2.0 1.3 0.9 0.9 0.4 2.6 0.9 0.3 8.3 2.2 2.8 39.5 1.2 26.5 0.9 0.9 1.0 6.5 26.4 1.6 0.2 0.3 0.6 ADCY4 AC4 ENSG00000129467 "Adenylate cyclase 4" Q8NFM4 14 24318349-24335093 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 90.9;Endothelial cells: 74.6;Hepatic stellate cells: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 2.9" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.9" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 2.9;TIME: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB005070, HPA048344" Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB005070: AB_2273639, HPA048344: AB_2680366" "unprognostic (5.59e-2)" "unprognostic (1.34e-1)" "unprognostic (3.47e-4)" "prognostic favorable (8.20e-4)" "unprognostic (4.06e-1)" "unprognostic (2.82e-3)" "unprognostic (1.75e-4)" "unprognostic (8.58e-2)" "unprognostic (2.51e-2)" "unprognostic (7.88e-2)" "unprognostic (6.77e-2)" "unprognostic (7.87e-2)" "prognostic unfavorable (7.01e-4)" "unprognostic (8.02e-2)" "unprognostic (3.88e-2)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" 18.0 2.6 2.8 2.3 2.2 0.0 16.1 2.2 2.8 9.2 2.0 3.9 0.9 8.8 0.5 3.7 8.2 2.9 16.9 2.0 2.1 10.2 1.4 9.9 1.6 2.7 2.5 2.4 2.3 1.0 1.7 9.9 2.6 5.3 0.7 0.0 3.7 1.4 4.3 4.7 4.5 1.9 2.4 9.9 3.7 1.1 3.0 0.4 7.7 2.8 0.8 5.9 6.7 2.3 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.3 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.1 0.1 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.8 2.2 2.2 2.8 2.0 2.1 2.7 2.5 2.6 2.4 3.0 2.3 90.9 0.0 1.8 0.3 1.0 3.6 0.4 0.3 3.4 0.0 1.5 1.5 10.6 0.0 0.9 1.8 0.0 0.2 1.6 2.9 0.0 1.2 1.3 0.5 1.1 74.6 1.2 0.4 0.2 3.1 0.1 4.7 7.1 0.6 1.3 0.0 50.3 0.2 1.4 1.7 0.2 7.9 0.0 5.0 3.1 6.9 0.0 1.5 7.2 12.2 2.5 0.9 1.0 0.0 0.0 2.1 3.8 0.0 1.4 0.4 2.4 0.0 1.1 0.2 6.6 1.7 5.7 0.3 0.8 0.6 2.8 0.0 1.6 0.5 2.1 0.2 ADGRB3 "BAI3, KIAA0550" ENSG00000135298 "Adhesion G protein-coupled receptor B3" O60242 6 68635282-69389506 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 49.6;pituitary gland: 23.7" "Group enriched" "Detected in some" 10 "Astrocytes: 1795.3;Excitatory neurons: 3843.1;Inhibitory neurons: 2738.1;Oligodendrocyte precursor cells: 2036.3;Oligodendrocytes: 1210.5" "Cancer enriched" "Detected in single" 10 "glioma: 3.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "SCLC-21H: 8.8;SH-SY5Y: 19.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 8600 "Cluster 6: Brain - Smell perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.71e-1)" "unprognostic (9.01e-2)" "unprognostic (2.69e-1)" "unprognostic (3.72e-3)" "unprognostic (3.27e-2)" "unprognostic (1.04e-1)" "unprognostic (2.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.08e-1)" "unprognostic (1.36e-2)" "unprognostic (5.08e-5)" "unprognostic (4.93e-2)" "unprognostic (1.32e-1)" "unprognostic (1.55e-3)" "unprognostic (2.43e-1)" "unprognostic (1.01e-1)" "unprognostic (8.16e-3)" 0.8 3.9 21.1 0.8 25.5 0.0 0.6 49.6 29.7 1.3 0.0 4.3 0.4 2.2 0.9 0.7 0.9 0.9 1.9 31.1 12.1 1.0 0.5 1.7 0.0 0.0 0.6 1.6 0.3 0.1 23.7 0.1 1.1 1.0 1.3 7.1 1.2 1.4 0.3 0.4 1.4 3.3 0.0 0.6 1.3 1.9 18.2 0.1 0.8 1.4 0.0 2.6 1.4 19.1 0.0 0.0 2.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.0 0.0 1.2 1.0 0.0 0.0 8.8 19.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 21.1 25.5 49.6 29.7 31.1 12.1 0.0 0.6 1.1 0.0 18.2 19.1 3.1 0.0 0.0 1795.3 0.3 0.0 0.1 0.0 0.0 47.3 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.7 0.2 4.8 0.6 0.0 0.0 3843.1 0.0 0.0 2.1 0.0 0.0 0.0 0.8 3.6 0.0 0.0 0.0 2738.1 0.0 0.0 0.6 0.0 3.1 5.0 1.3 0.0 216.4 1.0 0.8 0.0 2036.3 1210.5 0.1 0.0 8.6 0.0 0.1 0.0 0.0 0.0 2.8 0.0 0.6 7.4 11.8 3.2 0.2 0.0 0.0 0.0 0.5 0.0 0.1 ADK AK ENSG00000156110 "Adenosine kinase" P55263 10 74151202-74709963 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Purine salvage" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 151.2" "Cell type enhanced" "Detected in all" "Excitatory neurons: 245.3;Inhibitory neurons: 287.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032876, HPA038391, HPA038409, HPA075222" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 920000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB032876: AB_2242229, HPA038391: AB_2675990, HPA038409: AB_10675798, HPA075222: " "unprognostic (1.55e-3)" "unprognostic (1.09e-1)" "unprognostic (1.88e-1)" "unprognostic (2.62e-2)" "unprognostic (2.52e-2)" "prognostic unfavorable (1.93e-4)" "prognostic favorable (9.91e-4)" "unprognostic (2.64e-1)" "unprognostic (2.88e-1)" "unprognostic (1.55e-1)" "unprognostic (8.15e-3)" "unprognostic (2.51e-1)" "unprognostic (1.89e-3)" "unprognostic (2.03e-1)" "unprognostic (2.88e-2)" "unprognostic (4.97e-3)" "unprognostic (2.95e-2)" 23.9 15.5 13.0 16.9 18.7 28.6 27.4 13.5 17.7 17.5 11.6 17.9 16.9 10.8 16.5 47.3 16.5 11.4 27.2 13.9 15.2 35.8 151.2 24.4 22.8 14.0 15.0 8.3 18.8 44.2 14.9 26.6 16.5 14.9 19.5 16.1 20.0 16.0 41.5 33.9 12.4 14.8 14.2 15.0 12.1 15.5 14.1 27.0 38.2 47.1 34.5 24.5 24.7 15.8 177.3 37.4 37.2 50.5 37.1 54.7 88.2 140.8 105.4 103.8 114.5 114.0 172.6 86.3 34.2 57.7 51.3 151.1 44.1 150.1 167.0 59.1 51.3 55.6 59.8 122.8 41.7 87.6 22.5 51.1 95.5 77.4 191.7 79.0 91.2 38.7 41.8 28.4 78.8 101.7 102.5 129.0 9.9 80.0 276.3 100.6 63.7 69.4 117.1 92.7 29.5 33.8 63.6 239.7 49.5 34.7 159.7 69.3 82.8 34.3 67.0 93.2 123.0 40.5 48.3 98.1 65.0 127.6 22.1 2.3 34.2 4.1 12.9 65.5 29.9 103.7 28.2 24.1 83.1 155.0 21.3 19.2 11.1 20.7 80.4 57.6 55.7 36.3 13.0 18.7 13.5 17.7 13.9 15.2 14.0 15.0 16.5 14.2 14.1 15.8 9.8 83.3 75.8 136.5 84.2 94.2 73.5 102.0 105.9 16.3 26.2 26.0 67.8 38.6 72.4 31.3 56.3 136.7 25.9 11.0 92.0 83.2 80.7 40.6 18.8 14.9 10.8 27.7 245.3 67.5 139.5 27.0 23.0 55.6 21.5 9.7 17.2 130.1 39.3 11.8 287.7 12.1 44.7 25.2 50.0 26.9 16.8 33.7 48.0 198.6 44.1 14.1 11.3 140.8 165.4 62.7 10.4 12.0 39.1 92.1 5.0 64.5 33.5 25.0 6.6 20.4 26.0 17.4 14.3 96.7 97.0 107.3 32.7 17.0 20.5 66.3 AFAP1L1 FLJ36748 ENSG00000157510 "Actin filament associated protein 1 like 1" Q8TED9 5 149271859-149343637 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 31.6" "Cell type enhanced" "Detected in many" "Adipocytes: 62.4;Cardiomyocytes: 39.3;Early spermatids: 105.4;Endothelial cells: 72.0;Extravillous trophoblasts: 47.1;Hepatic stellate cells: 47.2;Late spermatids: 50.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 42.6;HUVEC TERT2: 20.8;TIME: 33.9;WM-115: 79.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.91e-1)" "unprognostic (7.80e-2)" "prognostic unfavorable (2.84e-4)" "unprognostic (1.20e-1)" "unprognostic (3.44e-1)" "unprognostic (2.61e-1)" "unprognostic (1.41e-3)" "unprognostic (5.25e-2)" "unprognostic (3.14e-1)" "unprognostic (1.09e-2)" "unprognostic (4.00e-1)" "unprognostic (9.64e-2)" "unprognostic (3.07e-3)" "unprognostic (1.52e-3)" "unprognostic (1.97e-1)" "unprognostic (1.88e-1)" "unprognostic (9.88e-2)" 23.9 2.8 1.7 2.1 0.9 0.1 15.2 1.1 1.3 4.2 1.0 3.5 0.8 7.1 0.6 4.3 10.1 4.0 26.1 0.9 1.0 4.1 2.1 13.3 2.3 1.4 1.1 3.3 1.0 6.1 2.4 14.4 1.4 3.3 0.7 1.3 3.4 1.9 31.6 6.0 3.4 3.5 1.1 2.9 2.4 2.3 1.8 3.4 7.4 16.6 0.8 4.6 3.7 0.9 7.0 2.4 0.1 0.3 9.9 2.1 42.6 1.5 5.5 5.4 8.9 0.1 4.1 0.0 3.3 2.5 13.7 1.4 0.8 6.2 2.2 0.0 1.0 1.6 0.9 0.0 5.2 0.0 0.1 7.3 1.0 3.0 11.6 4.3 20.8 0.0 0.0 0.2 2.1 0.0 0.0 0.0 1.0 0.0 5.4 0.0 0.0 0.0 3.5 1.1 0.7 1.1 4.4 0.1 14.8 1.5 0.2 0.4 33.9 2.5 7.7 0.1 1.2 0.0 0.0 0.0 0.5 0.1 79.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.7 0.9 1.1 1.3 0.9 1.0 1.4 1.1 1.4 1.1 1.8 0.9 62.4 0.0 1.3 0.3 0.2 1.5 1.4 4.6 0.0 0.3 0.4 0.5 39.3 1.5 4.1 0.0 0.0 14.2 0.2 0.0 0.0 0.3 105.4 0.3 0.4 72.0 0.0 0.0 2.9 0.0 47.1 4.5 0.0 0.2 1.3 0.0 47.2 0.6 2.7 0.0 1.2 0.0 0.0 4.2 1.3 50.4 9.6 0.7 7.2 10.3 0.0 0.5 0.0 2.0 0.3 0.0 0.0 15.8 0.0 4.0 0.0 0.8 6.4 5.3 13.1 4.6 4.0 0.5 4.8 0.3 1.4 6.4 0.5 1.8 0.0 5.4 AFAP1L2 "Em:AC005383.4, FLJ14564, KIAA1914, XB130" ENSG00000169129 "Actin filament associated protein 1 like 2" Q8N4X5 10 114294824-114404756 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 64.5;parathyroid gland: 68.7;thyroid gland: 82.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 40.5;Microglial cells: 34.7;Oligodendrocyte precursor cells: 122.6" "Cancer enhanced" "Detected in all" "thyroid cancer: 39.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 1.6;T-cells: 1.8" "Cell line enhanced" "Detected in many" "A-431: 74.4;CAPAN-2: 77.4;EFO-21: 56.4;HaCaT: 98.7;RPMI-8226: 51.3;RPTEC TERT1: 59.7" "Low region specificity" "Detected in all" HPA037843 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Cytosol" "HPA037843: AB_10669990" "unprognostic (2.31e-3)" "unprognostic (1.30e-1)" "unprognostic (2.02e-1)" "unprognostic (5.06e-3)" "unprognostic (4.14e-2)" "unprognostic (9.80e-2)" "unprognostic (9.88e-2)" "unprognostic (1.08e-1)" "unprognostic (1.36e-1)" "unprognostic (1.32e-1)" "prognostic unfavorable (3.76e-4)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.55e-5)" "unprognostic (1.11e-1)" "unprognostic (3.88e-2)" "unprognostic (1.72e-1)" "unprognostic (1.86e-1)" 7.6 2.4 15.7 4.2 12.9 0.1 10.2 21.5 13.1 21.8 5.9 13.0 3.9 23.9 13.2 9.3 22.9 4.5 4.7 11.8 12.4 17.6 1.7 5.3 4.3 12.9 12.8 15.1 11.9 68.7 2.4 18.4 13.6 13.1 5.1 3.7 6.9 23.9 3.0 9.8 6.4 18.9 13.6 64.5 5.9 1.4 13.3 13.5 82.2 4.4 7.6 5.9 14.7 13.5 74.4 10.8 10.0 0.1 0.0 0.0 0.0 0.0 0.5 0.4 0.4 0.1 77.4 0.1 56.4 0.6 1.1 98.7 0.2 27.2 0.2 1.5 0.1 0.0 0.7 0.0 3.0 0.0 2.7 0.0 28.9 8.1 7.1 0.3 0.3 2.8 0.0 0.2 0.0 3.1 1.9 0.1 0.5 2.0 0.5 0.9 0.8 51.3 59.7 0.6 0.3 0.5 2.3 1.7 2.9 16.0 0.0 0.1 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.0 1.1 1.6 1.1 1.2 0.0 1.6 0.3 0.9 0.1 0.4 0.0 0.1 1.8 0.6 15.7 12.9 21.5 13.1 11.8 12.4 12.9 12.8 13.6 13.6 13.3 13.5 14.6 0.0 0.0 0.7 1.2 12.4 7.3 3.1 5.2 0.8 1.8 5.3 2.2 0.0 1.8 40.5 0.0 1.5 2.4 8.1 0.0 0.6 1.0 5.3 7.4 14.5 0.0 0.8 6.5 14.3 1.2 10.7 3.1 9.5 0.0 0.3 13.2 0.0 0.5 1.7 10.1 1.8 0.0 0.0 3.7 3.0 3.1 0.5 5.4 34.7 0.6 3.2 0.0 122.6 0.6 23.2 1.7 1.9 0.1 3.7 2.2 0.4 1.5 0.6 19.7 21.4 24.7 0.0 0.8 2.3 6.8 0.3 3.4 2.4 2.2 4.3 AGMO "FLJ16237, TMEM195" ENSG00000187546 "Alkylglycerol monooxygenase" Q6ZNB7 7 15200317-15562015 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 122.5" "Cell type enhanced" "Detected in some" "Hepatocytes: 83.0;Oligodendrocyte precursor cells: 33.7;Oligodendrocytes: 38.5;Proximal enterocytes: 30.5;Proximal tubular cells: 16.9" "Cancer enriched" "Detected in many" 5 "liver cancer: 15.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.4" "Cell line enhanced" "Detected in some" "HSkMC: 3.5;Karpas-707: 7.7;NTERA-2: 3.5;SCLC-21H: 3.2;TIME: 4.0;WM-115: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057900 Uncertain Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 17: WM-115 - Nervous system development" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA057900: " "unprognostic (2.82e-1)" "unprognostic (9.28e-2)" "unprognostic (5.60e-3)" "unprognostic (1.44e-4)" "unprognostic (7.52e-2)" "unprognostic (1.07e-2)" "unprognostic (3.61e-2)" "unprognostic (6.56e-2)" "unprognostic (3.31e-1)" "unprognostic (3.35e-1)" "unprognostic (4.18e-3)" "unprognostic (3.24e-1)" "unprognostic (1.64e-1)" "unprognostic (2.04e-2)" "unprognostic (3.45e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" 2.8 0.1 0.9 0.6 2.4 0.1 1.8 0.7 1.9 0.1 0.1 1.2 9.7 0.1 14.5 0.1 0.1 3.6 0.4 0.7 1.4 8.9 122.5 0.2 0.5 1.5 1.4 0.1 0.1 0.0 0.4 0.8 1.5 0.0 0.6 0.1 0.2 0.1 0.3 0.2 14.9 0.1 0.9 0.0 0.3 3.0 1.8 0.2 0.4 0.4 0.1 1.2 0.1 4.1 0.0 2.2 0.0 1.9 0.2 2.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.1 3.5 0.0 0.0 0.0 0.0 1.2 0.0 0.7 3.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 4.0 1.3 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 15.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.9 2.4 0.7 1.9 0.7 1.4 1.5 1.4 1.5 0.9 1.8 4.1 10.0 0.0 0.0 6.8 0.3 0.1 0.1 0.7 0.0 0.0 0.2 0.3 0.1 11.5 0.4 3.7 0.0 0.1 0.1 0.5 0.0 0.0 1.3 0.3 0.1 1.2 1.8 2.7 1.3 0.0 0.2 1.2 0.0 0.0 0.0 0.0 1.1 83.0 0.1 0.0 1.7 0.4 0.0 1.6 0.5 1.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 33.7 38.5 0.9 0.1 0.0 0.0 0.0 30.5 16.9 0.3 0.0 6.6 0.4 2.4 1.7 6.4 0.1 0.0 0.1 0.2 0.1 0.6 0.0 AGXT2 AGT2 ENSG00000113492 "Alanine--glyoxylate aminotransferase 2" Q9BYV1 5 34998101-35048135 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 44 "kidney: 207.9;liver: 123.5" "Group enriched" "Detected in some" 5 "Hepatocytes: 105.9;Proximal tubular cells: 359.5" "Group enriched" "Detected in some" 112 "liver cancer: 9.2;renal cancer: 12.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA037382 Enhanced NA NA 13000 "Cluster 81: Kidney & Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA037382: AB_10670851" "unprognostic (2.61e-1)" "unprognostic (1.40e-2)" "prognostic favorable (7.47e-4)" "unprognostic (8.24e-2)" "unprognostic (1.28e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 207.9 123.5 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 2.8 0.0 9.2 0.0 0.0 0.0 0.0 45.0 0.0 0.0 0.0 0.1 0.1 0.0 2.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 105.9 0.0 0.0 0.2 0.6 0.0 2.4 0.0 0.0 0.3 1.6 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 1.2 0.4 0.0 0.0 6.7 359.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.3 0.0 AHSG "A2HS, FETUA, HSGA" ENSG00000145192 "Alpha 2-HS glycoprotein" P02765 3 186613060-186621318 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Mineral balance" "Cancer-related genes, Disease variant, Hypotrichosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4302 "liver: 5817.6" "Cell type enriched" "Detected in some" 38 "Hepatocytes: 1242.5" "Cancer enriched" "Detected in some" 284 "liver cancer: 1231.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 78 "Hep G2: 2287.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001524, HPA001525, CAB026209" Enhanced Enhanced "Golgi apparatus" "Secreted to blood" NA NA 864000000000 110000000000 "Cluster 48: NK-cells - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Golgi apparatus" "CAB026209: , HPA001524: AB_1078851, HPA001525: AB_1078849" "unprognostic (6.40e-2)" "unprognostic (1.31e-1)" "unprognostic (2.03e-2)" "unprognostic (3.20e-2)" "unprognostic (1.07e-2)" "unprognostic (1.16e-2)" "unprognostic (7.47e-3)" "unprognostic (3.05e-1)" "unprognostic (5.27e-2)" "unprognostic (8.64e-2)" "unprognostic (3.99e-7)" "unprognostic (5.21e-2)" "unprognostic (5.21e-2)" "unprognostic (1.04e-1)" 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 1.3 5817.6 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.2 0.0 0.7 0.7 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.9 1.0 2287.3 0.0 4.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.1 3.5 0.0 0.0 1.1 0.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.4 0.0 1.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.2 0.0 0.0 0.0 0.2 0.0 0.1 3.9 0.2 4.3 0.2 0.1 0.9 0.0 32.0 0.6 0.6 2.4 0.1 0.0 0.1 0.0 0.0 28.2 1242.5 1.3 0.0 0.1 0.0 0.0 32.4 0.0 23.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.9 2.0 0.0 0.0 0.1 AIF1 "AIF-1, Em:AF129756.17, IBA1, IRT-1" ENSG00000204472 "Allograft inflammatory factor 1" P55008 6 31615217-31617021 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 235.0;lymphoid tissue: 346.6" "Group enriched" "Detected in many" 22 "Hofbauer cells: 1777.1;Kupffer cells: 2140.2;Langerhans cells: 1359.1;Macrophages: 1494.0;monocytes: 1022.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 26 "classical monocyte: 3823.3;intermediate monocyte: 6550.1;myeloid DC: 2043.3;neutrophil: 2943.0;non-classical monocyte: 7744.5" "Group enriched" "Detected in all" 74 "dendritic cells: 2043.3;granulocytes: 2943.0;monocytes: 7744.5" "Group enriched" "Detected in some" 4 "HEL: 204.6;HMC-1: 329.6;NB-4: 264.7;THP-1: 184.2;U-937: 114.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049234, HPA062949" Enhanced Uncertain Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "HPA049234: AB_2680685, HPA062949: AB_2732694" "unprognostic (3.20e-2)" "unprognostic (7.21e-3)" "unprognostic (6.11e-2)" "unprognostic (2.33e-2)" "unprognostic (2.46e-1)" "unprognostic (1.13e-1)" "unprognostic (6.98e-2)" "unprognostic (4.83e-2)" "unprognostic (2.72e-2)" "unprognostic (7.56e-2)" "unprognostic (1.41e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.29e-1)" "unprognostic (1.02e-2)" "unprognostic (9.59e-2)" "unprognostic (4.89e-2)" 79.6 46.6 24.9 182.3 25.5 235.0 47.2 26.6 33.0 29.3 32.2 48.3 36.4 17.1 12.1 18.7 19.7 61.3 21.1 25.0 31.3 74.3 81.2 99.3 116.8 45.1 36.4 14.4 12.4 12.9 17.3 109.5 36.8 22.3 57.2 3.9 20.3 24.0 6.1 11.7 44.5 74.7 34.3 346.6 22.2 8.7 32.1 69.1 13.8 16.6 57.1 95.3 13.5 42.7 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 204.6 0.0 0.0 0.0 30.0 329.6 0.0 0.0 0.0 0.0 0.0 0.0 51.6 0.9 0.2 0.0 0.0 2.3 264.7 0.4 0.0 0.0 35.9 0.4 8.9 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 184.2 0.1 0.0 0.2 0.1 0.3 0.2 0.0 1.3 0.2 114.6 0.0 33.1 3823.3 177.9 10.2 6550.1 12.7 57.5 10.8 9.3 2043.3 6.3 33.1 26.2 2943.0 14.5 7744.5 144.2 10.7 4449.8 24.9 25.5 26.6 33.0 25.0 31.3 45.1 36.4 36.8 34.3 32.1 42.7 12.0 25.6 59.6 0.0 39.2 32.5 0.7 0.0 0.6 0.1 5.3 24.3 7.5 18.6 19.2 42.3 0.0 11.1 31.2 1.0 0.0 0.3 1.9 0.6 0.7 28.7 1.2 65.0 0.0 0.4 15.4 20.6 0.5 0.4 68.3 0.4 35.3 13.4 1777.1 0.0 0.0 0.1 0.0 2140.2 1359.1 4.9 7.5 1494.0 39.2 10.3 1022.6 0.0 32.0 0.5 0.1 0.2 11.1 0.7 7.2 0.4 0.3 4.2 10.2 0.1 52.6 4.7 6.5 0.5 1.5 2.1 28.3 22.7 46.1 1.9 0.6 0.3 AKAP6 "ADAP6, AKAP100, KIAA0311, mAKAP, PRKA6" ENSG00000151320 "A-kinase anchoring protein 6" Q13023 14 32329298-32837684 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.8;heart muscle: 54.6;skeletal muscle: 47.5;tongue: 50.7" "Group enriched" "Detected in many" 6 "Excitatory neurons: 601.6;Inhibitory neurons: 663.1;Oligodendrocyte precursor cells: 412.7;Oligodendrocytes: 1162.5" "Cancer enhanced" "Detected in many" "glioma: 2.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "naive B-cell: 3.5" "Lineage enriched" "Detected in single" 6 "B-cells: 3.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 15.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001983, HPA048741" Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "CAB001983: , HPA048741: AB_2680506" "unprognostic (1.99e-1)" "unprognostic (9.92e-2)" "unprognostic (1.88e-1)" "unprognostic (1.37e-1)" "unprognostic (2.52e-1)" "unprognostic (4.33e-2)" "unprognostic (1.41e-4)" "unprognostic (1.81e-3)" "unprognostic (1.93e-2)" "unprognostic (4.49e-3)" "unprognostic (1.24e-3)" "unprognostic (3.54e-1)" "unprognostic (3.33e-16)" "unprognostic (8.57e-2)" "unprognostic (1.27e-1)" "unprognostic (5.14e-3)" "unprognostic (1.79e-3)" 1.6 5.6 21.0 2.5 31.4 0.5 4.6 20.3 24.6 1.6 0.0 5.5 1.8 3.9 5.6 5.4 2.9 3.7 54.6 16.9 36.7 2.9 2.1 2.3 0.8 52.0 34.9 2.5 0.8 3.5 3.6 4.5 51.9 2.0 2.2 13.6 2.6 1.2 47.5 1.2 2.4 7.7 22.4 0.8 2.0 5.9 34.8 0.9 4.8 50.7 0.7 4.2 1.5 59.8 0.3 0.8 1.0 0.9 0.2 1.7 0.2 1.3 3.6 0.2 0.4 1.1 1.0 1.4 0.9 15.8 0.6 0.8 1.2 1.4 0.5 1.3 1.0 1.3 1.5 1.1 0.5 0.1 0.3 1.8 1.3 0.0 0.4 0.6 0.1 2.1 0.3 4.1 1.1 0.8 0.7 0.2 0.2 1.1 1.1 0.7 4.9 0.6 0.4 1.2 5.2 4.2 1.1 0.7 3.2 0.7 2.9 0.1 0.3 0.2 0.8 0.8 0.5 2.5 2.4 0.6 1.5 0.1 5.4 0.3 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.2 3.5 0.4 0.6 0.5 0.1 0.1 0.4 0.0 0.3 21.0 31.4 20.3 24.6 16.9 36.7 52.0 34.9 51.9 22.4 34.8 59.8 0.6 6.4 2.7 111.3 2.2 2.3 2.9 1.0 5.2 49.2 8.7 3.0 108.0 0.0 4.9 1.8 50.1 0.8 0.1 1.1 0.0 0.8 32.4 6.7 0.4 1.7 1.2 0.0 601.6 0.5 0.3 6.3 0.0 1.4 1.3 0.6 1.1 2.7 1.2 26.9 663.1 0.6 4.1 0.6 1.6 13.7 14.6 1.1 7.2 23.4 0.7 2.5 0.0 412.7 1162.5 0.3 0.1 33.1 2.0 1.1 1.9 1.5 23.6 21.5 19.7 25.8 14.3 25.9 1.3 1.1 1.6 0.4 0.6 3.4 0.9 0.9 AKR1A1 "ALR, DD3" ENSG00000117448 "Aldo-keto reductase family 1 member A1" P14550 1 45550543-45570049 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 872.9;Proximal tubular cells: 1215.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006246, HPA017919, HPA019649, HPA027734" Approved Supported Nucleoplasm,Cytosol NA NA 7600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "CAB006246: AB_425840, HPA017919: AB_1844695, HPA019649: AB_1844696, HPA027734: AB_10600976" "unprognostic (1.73e-1)" "prognostic favorable (2.66e-6)" "unprognostic (4.03e-1)" "prognostic favorable (2.92e-4)" "unprognostic (1.17e-1)" "unprognostic (1.77e-2)" "unprognostic (6.54e-3)" "unprognostic (1.31e-3)" "unprognostic (2.52e-1)" "unprognostic (1.24e-1)" "unprognostic (1.83e-1)" "unprognostic (8.43e-2)" "unprognostic (4.51e-2)" "unprognostic (1.56e-2)" "unprognostic (2.46e-1)" "unprognostic (2.89e-2)" "unprognostic (4.57e-2)" 68.8 72.7 37.6 73.4 41.4 48.6 123.1 41.3 38.9 84.0 49.1 106.6 188.7 59.9 90.7 151.9 88.9 61.7 67.6 37.2 41.0 323.5 323.7 75.8 97.3 44.0 39.3 61.8 158.1 60.8 99.4 63.9 44.1 75.9 115.4 23.2 123.0 60.0 46.5 73.5 171.6 79.0 43.3 92.5 112.9 21.1 44.4 77.3 80.7 42.6 117.0 72.3 70.9 53.2 74.3 94.5 91.2 73.7 173.1 124.8 67.9 78.3 178.0 68.8 133.5 40.1 50.3 179.5 68.5 86.2 71.6 94.5 94.0 118.3 60.0 74.3 92.6 101.2 82.2 167.8 152.0 132.4 102.7 140.2 104.7 87.0 157.4 123.4 154.7 125.1 59.4 131.2 77.1 49.1 147.3 61.2 106.0 219.4 68.2 170.1 119.5 211.9 185.5 89.3 117.5 65.3 71.8 271.1 108.5 113.2 80.3 72.3 97.2 30.2 72.0 113.1 54.2 97.0 140.5 87.6 59.1 168.7 26.6 141.8 229.5 45.4 65.3 224.5 71.6 99.8 59.6 63.5 196.8 108.9 51.4 52.4 11.1 66.1 174.8 170.0 81.9 182.7 37.6 41.4 41.3 38.9 37.2 41.0 44.0 39.3 44.1 43.3 44.4 53.2 53.0 48.1 57.3 7.2 96.6 49.2 99.3 210.0 87.6 21.2 121.0 94.7 46.1 95.8 173.8 79.1 37.5 115.2 45.1 113.7 181.9 195.9 5.4 48.7 49.1 58.6 118.4 48.0 8.3 156.5 142.1 82.0 135.5 54.7 112.1 59.2 78.1 294.5 399.3 16.8 7.1 201.9 118.0 141.8 153.7 9.6 68.3 142.1 81.8 20.6 140.3 33.6 49.4 9.0 16.2 123.6 199.9 56.1 187.2 115.1 872.9 1215.0 131.6 38.0 6.6 40.3 132.5 5.9 32.2 158.5 47.0 67.9 49.5 59.0 198.5 129.6 ALDH3A2 "ALDH10, FALDH, SLS" ENSG00000072210 "Aldehyde dehydrogenase 3 family member A2" P51648 17 19648136-19685760 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant, Ichthyosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 288.6" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 287.4;Squamous epithelial cells: 232.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 285.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014769, CAB020692" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 32000 "Cluster 14: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum, Cytosol" "CAB020692: , HPA014769: AB_1844728" "unprognostic (1.42e-1)" "unprognostic (7.62e-2)" "unprognostic (7.77e-2)" "unprognostic (2.49e-2)" "unprognostic (4.59e-1)" "unprognostic (1.64e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-2)" "unprognostic (2.23e-1)" "unprognostic (3.93e-3)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "prognostic favorable (3.85e-8)" "unprognostic (4.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.42e-2)" "unprognostic (1.26e-1)" 75.2 203.0 23.1 15.2 32.5 9.3 34.9 24.8 27.7 49.4 71.7 49.6 68.1 29.4 41.7 131.3 38.3 70.5 44.6 29.0 27.9 173.0 288.6 59.1 14.9 23.3 26.3 32.3 52.3 40.6 21.9 11.8 23.5 75.0 36.5 40.8 61.7 41.5 53.0 207.6 71.8 30.2 25.1 19.4 81.5 26.9 24.8 23.0 75.1 100.9 36.4 24.2 40.5 33.6 27.7 147.0 29.2 58.5 88.7 89.4 19.1 12.3 29.9 24.4 27.6 63.2 52.5 12.3 35.9 50.5 29.3 99.0 59.8 125.2 19.9 36.2 42.5 5.3 120.9 142.8 12.2 30.6 5.4 42.9 137.6 22.9 12.2 49.7 49.2 25.5 2.2 0.6 37.3 45.3 0.7 25.2 32.3 285.4 78.5 38.6 64.1 25.3 17.5 132.3 46.3 30.4 98.9 38.4 35.3 152.2 78.1 35.0 46.7 10.1 28.7 68.8 45.6 11.3 28.6 15.5 47.4 0.3 48.3 0.8 21.1 17.5 6.3 18.3 9.9 5.2 6.0 6.1 20.7 4.9 6.8 6.3 2.2 15.0 20.6 1.3 11.3 11.0 23.1 32.5 24.8 27.7 29.0 27.9 23.3 26.3 23.5 25.1 24.8 33.6 22.1 176.3 86.5 14.7 13.3 57.1 143.9 85.1 287.4 15.3 13.6 24.0 54.1 105.8 86.5 33.1 12.5 12.5 8.2 48.9 43.0 97.5 79.6 47.5 13.4 19.5 16.2 8.2 30.5 52.0 4.6 39.9 87.7 36.9 29.7 34.6 13.6 116.7 24.6 6.7 20.1 27.7 26.4 21.7 15.1 19.5 55.9 23.5 7.2 13.1 25.7 105.9 8.2 19.6 29.1 43.9 28.7 80.5 28.6 104.2 90.6 119.2 59.2 21.4 13.1 70.1 22.1 15.5 24.0 232.6 90.2 1.4 13.2 29.1 46.0 51.4 ALDH4A1 "ALDH4, P5CDh" ENSG00000159423 "Aldehyde dehydrogenase 4 family member A1" P30038 1 18871430-18902724 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Proline metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 200.4;liver: 436.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 78.0;Hepatocytes: 385.1;Proximal tubular cells: 279.4;Syncytiotrophoblasts: 86.6" "Cancer enhanced" "Detected in all" "liver cancer: 72.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Hep G2: 83.7;SK-BR-3: 85.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004645, HPA006401, HPA072759" Enhanced Supported Mitochondria NA NA 58000 "Cluster 7: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB004645: AB_425775, HPA006401: AB_1844731, HPA072759: " "unprognostic (1.17e-1)" "prognostic favorable (5.06e-4)" "unprognostic (1.38e-2)" "unprognostic (4.16e-2)" "unprognostic (3.15e-1)" "unprognostic (7.67e-2)" "unprognostic (1.28e-1)" "unprognostic (6.18e-2)" "unprognostic (1.92e-1)" "unprognostic (1.09e-2)" "unprognostic (1.02e-1)" "unprognostic (2.06e-1)" "unprognostic (4.27e-3)" "unprognostic (9.41e-3)" "unprognostic (3.83e-1)" "unprognostic (2.69e-3)" "unprognostic (9.34e-2)" 70.8 16.1 73.9 3.9 88.9 11.7 21.6 73.8 95.9 12.6 106.5 6.8 1.6 9.8 4.7 36.3 8.3 5.5 33.0 68.2 73.8 200.4 436.6 6.2 3.4 72.9 82.8 7.3 4.6 23.0 9.7 13.2 70.0 29.5 2.7 6.5 9.1 27.1 74.2 19.2 4.7 7.1 65.6 7.5 12.5 3.2 92.4 11.7 7.1 74.8 4.2 19.3 16.8 66.1 12.7 17.8 9.5 29.2 40.0 5.7 25.2 13.1 7.1 11.8 9.5 13.7 8.9 8.8 16.6 15.6 5.7 34.0 16.7 35.4 4.5 4.8 15.9 5.9 5.0 83.7 12.6 4.4 15.1 15.6 19.2 6.5 6.6 9.0 13.5 14.0 21.0 5.7 8.1 32.3 4.3 20.2 4.7 26.0 10.1 27.9 8.4 10.0 12.1 32.0 19.6 7.6 21.9 85.0 16.1 14.7 38.7 6.3 11.3 10.2 14.0 12.2 4.5 7.1 17.9 2.5 3.4 33.7 13.5 0.0 2.7 1.5 0.6 3.6 0.5 0.8 0.3 0.8 4.4 0.7 0.2 0.5 0.3 0.1 2.0 1.5 0.6 1.5 73.9 88.9 73.8 95.9 68.2 73.8 72.9 82.8 70.0 65.6 92.4 66.1 2.6 0.0 2.8 27.1 4.3 7.5 17.9 12.5 17.6 3.7 9.8 8.5 20.9 34.3 2.9 46.0 10.4 78.0 2.0 2.0 46.9 6.5 0.5 1.1 1.7 3.1 2.4 32.2 1.2 0.9 12.6 3.2 7.7 3.9 4.5 2.1 15.4 385.1 13.8 20.2 1.6 3.6 6.1 17.2 1.4 0.6 1.2 4.7 3.6 1.9 10.9 14.0 1.0 5.5 1.3 2.5 1.8 2.6 4.4 12.0 0.3 279.4 1.7 4.8 6.6 2.6 4.7 2.2 3.9 21.7 5.4 86.6 2.6 4.5 4.0 9.5 ALDH6A1 MMSDH ENSG00000119711 "Aldehyde dehydrogenase 6 family member A1" Q02252 14 74056847-74084492 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "kidney: 379.1;liver: 367.1" "Cell type enhanced" "Detected in all" "Distal tubular cells: 201.5;Hepatocytes: 523.6;Proximal tubular cells: 962.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 43.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 43.2" "Cell line enhanced" "Detected in all" "T-47d: 57.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029072, HPA029073, HPA029074, HPA029075" Enhanced Enhanced Mitochondria No No 37000 "Cluster 2: Granulocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA029072: AB_10599176, HPA029073: AB_10601877, HPA029074: AB_10601000, HPA029075: AB_10602005" "unprognostic (1.45e-1)" "unprognostic (5.38e-2)" "unprognostic (6.89e-2)" "unprognostic (6.95e-3)" "unprognostic (1.46e-1)" "unprognostic (7.93e-2)" "unprognostic (1.11e-3)" "prognostic favorable (4.22e-4)" "unprognostic (1.58e-1)" "unprognostic (9.10e-2)" "unprognostic (3.11e-2)" "unprognostic (2.13e-1)" "prognostic favorable (2.00e-15)" "unprognostic (4.59e-1)" "unprognostic (1.92e-1)" "unprognostic (6.05e-3)" "unprognostic (1.12e-1)" 38.7 14.7 58.6 4.8 66.0 3.3 14.4 58.8 59.3 17.3 61.4 15.2 26.6 11.4 9.8 9.8 12.8 9.4 40.3 51.0 54.0 379.1 367.1 9.4 5.1 63.3 54.0 28.3 23.4 37.0 6.6 7.6 55.6 25.4 15.8 15.2 19.8 16.1 27.5 6.2 23.4 9.0 56.4 5.4 24.0 17.1 69.8 5.7 28.3 34.8 5.3 11.4 7.0 62.6 8.9 7.8 11.0 23.5 39.3 19.2 17.5 6.3 11.8 6.8 11.5 17.3 10.2 10.5 13.6 13.5 5.3 4.8 24.9 7.0 14.5 9.5 3.5 5.1 8.0 19.2 45.0 2.7 2.4 28.2 12.0 8.7 20.7 17.0 12.0 23.7 8.1 14.7 4.6 36.2 7.6 4.0 8.7 32.6 5.2 15.1 11.2 14.6 9.2 5.8 4.4 7.0 21.0 21.9 5.7 18.0 57.5 9.6 3.8 7.4 9.0 11.7 2.4 9.3 18.9 10.2 9.9 3.2 7.3 29.1 6.2 43.2 6.9 4.8 10.6 7.2 7.8 8.4 9.2 6.1 9.9 7.0 2.4 9.7 4.2 5.3 6.1 4.9 58.6 66.0 58.8 59.3 51.0 54.0 63.3 54.0 55.6 56.4 69.8 62.6 15.4 38.5 60.4 24.5 11.8 9.2 26.8 10.0 20.5 20.6 28.4 18.9 81.4 67.2 22.9 66.2 4.2 31.0 7.1 18.9 201.5 11.6 23.4 26.2 27.5 27.0 16.9 28.6 5.5 3.1 14.8 25.9 34.7 90.2 7.6 27.1 87.4 523.6 17.7 11.8 10.0 39.3 8.2 26.5 8.9 19.0 28.9 13.4 24.9 1.9 15.8 98.5 9.2 12.5 23.4 4.1 16.3 48.2 8.0 27.6 55.3 962.4 15.4 17.0 13.1 25.6 16.9 11.0 4.2 25.2 7.4 30.6 11.0 10.2 35.7 17.2 ALOX5AP FLAP ENSG00000132965 "Arachidonate 5-lipoxygenase activating protein" P20292 13 30713478-30764426 "Disease related genes, Predicted membrane proteins" "Leukotriene biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 487.2;lung: 183.3;lymphoid tissue: 138.5" "Cell type enhanced" "Detected in many" "dendritic cells: 691.3;granulocytes: 609.1;Hofbauer cells: 492.2;Langerhans cells: 335.4;Macrophages: 637.0;NK-cells: 280.2;T-cells: 368.6" "Cancer enhanced" "Detected in all" "glioma: 49.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 9703.9;eosinophil: 4033.4;neutrophil: 4968.7;plasmacytoid DC: 3555.3" "Group enriched" "Detected in all" 8 "dendritic cells: 3555.3;granulocytes: 9703.9" "Cell line enhanced" "Detected in many" "HDLM-2: 658.4;HL-60: 352.3;HMC-1: 1072.9;THP-1: 434.2;U-937: 321.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026592 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA026592: AB_10601115" "unprognostic (1.17e-2)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (4.64e-3)" "unprognostic (7.18e-2)" "unprognostic (7.10e-2)" "unprognostic (7.79e-2)" "unprognostic (1.04e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (6.44e-4)" "unprognostic (7.83e-2)" "unprognostic (6.63e-2)" "prognostic unfavorable (5.68e-4)" "unprognostic (1.33e-1)" "unprognostic (3.19e-2)" "unprognostic (2.72e-2)" "unprognostic (2.59e-1)" 51.6 36.1 10.8 100.6 11.6 487.2 25.7 12.5 18.1 18.8 13.4 22.8 21.6 17.4 7.1 21.8 24.5 40.0 12.4 10.2 15.7 13.3 19.7 183.3 77.2 21.0 15.6 10.6 14.1 9.6 6.1 37.2 21.1 13.2 21.4 3.7 19.9 15.5 3.8 7.4 28.3 42.6 16.6 138.5 20.0 4.3 17.7 93.2 9.1 24.7 108.2 65.6 11.9 31.3 0.6 0.8 1.2 0.0 0.6 0.0 0.1 0.0 0.4 0.0 0.0 1.3 7.1 156.3 2.2 0.0 5.2 1.2 0.0 4.6 0.1 658.4 0.0 18.7 0.3 1.0 0.7 352.3 1072.9 0.8 0.2 0.1 37.9 8.1 1.4 33.3 0.1 3.2 1.9 0.1 19.8 12.7 0.0 0.0 0.2 3.2 3.9 12.4 1.4 0.3 10.2 0.1 0.2 0.3 0.9 2.3 0.0 434.2 1.1 0.0 3.2 0.3 2.6 66.2 0.5 103.8 1.0 321.1 1.4 9703.9 322.4 4033.4 546.0 17.2 808.3 477.9 536.4 449.0 198.5 489.2 271.6 260.7 4968.7 98.0 12.4 3555.3 843.9 775.2 10.8 11.6 12.5 18.1 10.2 15.7 21.0 15.6 21.1 16.6 17.7 31.3 3.5 41.7 102.0 0.0 117.6 23.7 2.6 1.8 1.2 0.0 3.3 9.1 4.1 10.0 23.7 0.0 0.0 3.1 691.3 4.0 15.6 2.3 5.6 14.3 0.7 17.2 26.4 27.1 0.4 1.0 4.0 11.2 21.4 0.7 609.1 1.9 7.1 1.8 492.2 0.0 0.4 2.0 4.1 144.3 335.4 4.5 4.7 637.0 42.7 13.1 217.1 0.1 280.2 0.5 0.3 6.4 3.1 4.1 31.1 1.5 7.3 2.0 11.1 0.1 32.9 4.4 4.0 0.4 1.1 1.7 24.7 4.9 368.6 0.0 2.0 1.4 AMBP "EDC1, HCP, HI30, IATIL, ITI, ITIL, ITILC, UTI" ENSG00000106927 "Alpha-1-microglobulin/bikunin precursor" P02760 9 114060127-114078328 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "liver: 10947.9" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 10517.4" "Cancer enriched" "Detected in many" 115 "liver cancer: 2620.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 173 "Hep G2: 1398.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001497, CAB069436, HPA075585" Approved Approved "Golgi apparatus,Vesicles,Cytosol" "Secreted to blood" NA NA 47000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Golgi apparatus, Cytosol" "CAB069436: AB_1611916, HPA001497: AB_1078144, HPA075585: " "unprognostic (6.92e-2)" "unprognostic (3.61e-1)" "unprognostic (4.95e-3)" "prognostic favorable (1.20e-4)" "unprognostic (9.79e-2)" "unprognostic (2.90e-1)" "unprognostic (1.04e-3)" "unprognostic (7.59e-2)" "unprognostic (2.83e-2)" "unprognostic (2.04e-1)" "unprognostic (2.14e-1)" "unprognostic (7.84e-2)" "unprognostic (4.36e-2)" "unprognostic (2.89e-3)" "unprognostic (4.66e-2)" "unprognostic (2.97e-3)" "unprognostic (9.45e-3)" 0.7 0.2 0.1 0.0 0.1 0.0 6.4 0.3 0.4 0.2 0.3 0.3 2.3 0.1 0.4 0.3 0.4 160.4 0.5 0.1 0.1 11.0 10947.9 0.3 0.0 0.1 0.1 0.2 125.3 0.0 0.2 0.4 0.1 0.2 0.5 0.2 0.1 0.0 0.2 0.3 0.7 0.0 0.1 3.1 2.6 1.0 0.1 0.1 0.4 0.0 0.2 0.1 0.2 0.0 0.0 6.7 0.1 0.0 0.2 0.1 0.0 0.0 0.5 0.0 0.0 1.8 0.0 1.8 2.1 0.2 0.9 0.5 0.0 0.0 0.0 3.2 0.0 3.0 1.0 1398.1 0.0 5.5 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.1 0.1 0.3 0.0 0.9 3.1 0.0 0.2 8.1 0.4 5.9 0.6 1.7 0.0 2.8 1.1 0.0 0.1 0.0 0.2 1.0 0.0 0.8 0.0 0.4 1.0 0.3 1.5 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 1.5 0.0 19.1 1.5 0.6 0.0 2.2 0.0 1.9 0.4 0.2 2585.0 0.6 1.8 0.0 0.1 0.0 0.6 3.9 216.5 30.4 0.2 0.1 10.0 2.4 219.2 0.1 28.2 0.8 0.1 0.0 1.0 0.0 0.0 181.3 10517.4 0.7 0.0 0.1 1.6 0.0 243.7 0.5 59.4 0.6 0.2 0.0 0.0 3.6 0.0 0.0 0.0 0.0 14.9 1.7 0.0 0.0 0.6 0.6 13.7 0.0 0.0 0.0 0.0 0.5 0.6 0.2 1.1 0.4 1.4 14.3 0.0 1.2 0.3 AMDHD1 MGC35366 ENSG00000139344 "Amidohydrolase domain containing 1" Q96NU7 12 95943331-95968720 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Histidine metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 60.7;skeletal muscle: 27.3" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 132.5" "Cancer enriched" "Detected in many" 14 "liver cancer: 23.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 46.6;HMC-1: 47.7;Karpas-707: 61.2;SiHa: 40.5;SK-BR-3: 46.1;U-266/70: 49.1;U-266/84: 62.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039720, HPA040149" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" No NA 1400000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "Nucleoplasm, Plasma membrane" "HPA039720: AB_10672967, HPA040149: " "unprognostic (4.81e-2)" "unprognostic (2.91e-1)" "unprognostic (1.53e-1)" "unprognostic (2.09e-2)" "unprognostic (1.80e-2)" "unprognostic (2.88e-2)" "unprognostic (2.33e-2)" "unprognostic (6.62e-3)" "unprognostic (1.06e-1)" "unprognostic (7.01e-2)" "unprognostic (3.35e-3)" "unprognostic (1.17e-1)" "unprognostic (4.63e-3)" "unprognostic (3.98e-2)" "unprognostic (1.70e-1)" "unprognostic (4.08e-3)" "unprognostic (2.61e-1)" 1.8 11.7 8.2 6.5 11.2 6.1 0.4 5.5 11.8 0.3 6.9 1.4 5.1 3.0 0.4 2.6 0.7 1.7 1.7 7.6 6.9 5.8 60.7 2.3 4.4 15.5 8.6 1.4 3.3 0.7 0.5 2.0 9.5 2.8 0.2 1.8 2.0 0.2 27.3 5.8 5.0 0.6 2.7 5.9 4.8 13.1 8.0 0.6 0.9 0.9 0.4 0.3 0.2 15.4 46.6 9.5 0.8 5.8 0.0 0.0 10.0 1.5 0.5 0.7 1.4 3.9 5.8 4.0 4.2 0.0 2.6 8.2 0.3 0.0 0.3 16.0 1.7 4.2 7.9 9.4 0.0 5.9 47.7 0.0 0.4 0.8 0.1 0.2 0.3 3.9 2.7 61.2 0.0 6.8 3.7 10.8 4.4 1.8 2.2 7.8 0.3 5.3 0.0 4.3 4.9 6.9 40.5 46.1 5.2 0.2 4.6 8.4 0.0 5.8 19.1 8.0 5.4 49.1 62.8 6.3 3.8 12.2 6.9 0.2 0.6 1.7 0.5 0.6 0.4 0.6 0.2 0.6 0.5 0.3 0.3 0.4 0.4 2.3 1.8 0.2 0.1 0.5 8.2 11.2 5.5 11.8 7.6 6.9 15.5 8.6 9.5 2.7 8.0 15.4 1.1 0.0 0.5 0.3 2.0 0.4 0.2 0.0 0.0 0.1 1.1 1.0 0.6 1.5 0.6 3.7 0.0 0.9 1.7 0.0 3.9 0.2 0.9 0.1 0.0 0.8 1.8 8.0 0.7 1.1 0.1 0.1 0.0 0.0 0.0 0.2 8.6 132.5 4.4 1.7 0.3 0.1 0.0 5.7 1.3 0.1 0.3 1.8 3.6 0.0 0.7 1.8 2.1 4.0 2.0 0.2 0.0 0.0 0.7 0.0 0.4 31.0 0.0 0.0 0.0 0.8 0.0 1.5 1.9 0.0 0.3 0.3 1.4 0.3 0.4 0.1 ANGPTL2 "ARP2, HARP" ENSG00000136859 "Angiopoietin like 2" Q9UKU9 9 127087348-127122635 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 47.4;Endothelial cells: 34.6;Fibroblasts: 99.7;Oligodendrocyte precursor cells: 35.2;Skeletal myocytes: 39.3;Smooth muscle cells: 43.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 140.4;ASC TERT1: 94.9;BJ hTERT+: 205.9;HSkMC: 98.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040933, HPA041299" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 2510000 2200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA040933: AB_10795530, HPA041299: AB_10794552" "unprognostic (5.46e-2)" "unprognostic (4.96e-3)" "unprognostic (1.11e-2)" "unprognostic (2.07e-2)" "unprognostic (8.79e-2)" "unprognostic (3.13e-2)" "unprognostic (1.79e-2)" "unprognostic (2.04e-2)" "unprognostic (3.31e-1)" "unprognostic (1.17e-3)" "unprognostic (2.34e-2)" "unprognostic (1.80e-2)" "prognostic unfavorable (3.32e-5)" "unprognostic (1.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.45e-2)" "unprognostic (4.15e-2)" 109.5 11.5 6.1 33.5 12.9 0.2 71.2 15.1 8.6 67.7 12.4 76.5 15.1 72.9 13.7 21.7 31.4 67.0 69.2 6.9 9.4 13.4 14.8 22.5 8.1 12.0 12.4 44.2 5.5 4.1 3.4 21.4 11.7 24.7 17.9 0.9 18.0 27.1 57.6 29.2 27.8 63.4 9.9 49.2 28.9 4.4 12.6 4.7 15.7 36.6 8.9 59.4 49.1 15.4 0.0 0.0 17.4 0.0 140.4 94.9 9.4 8.1 205.9 9.2 8.5 0.0 0.0 0.0 7.0 21.4 1.8 0.1 1.7 0.0 4.8 0.1 0.0 0.0 0.1 0.5 30.3 0.1 0.0 98.2 0.0 20.0 0.0 28.7 27.6 2.3 0.0 0.1 6.3 0.0 0.2 4.3 18.4 0.0 1.0 16.5 27.3 1.6 2.2 0.0 9.3 10.1 0.0 0.0 0.0 3.3 0.0 0.0 8.8 35.5 4.5 50.4 0.0 0.0 0.1 0.0 37.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 12.9 15.1 8.6 6.9 9.4 12.0 12.4 11.7 9.9 12.6 15.4 47.4 9.6 2.4 1.0 0.1 14.3 7.0 0.2 3.4 14.4 0.6 6.6 16.6 0.0 0.1 0.0 2.1 1.0 0.5 0.1 0.0 0.2 1.6 1.4 20.2 34.6 0.0 0.0 0.6 0.0 0.8 99.7 1.1 1.0 0.0 2.9 5.0 0.0 1.4 0.0 1.5 0.0 0.0 0.0 17.4 1.5 20.8 0.8 7.2 1.9 0.0 1.9 0.0 35.2 19.2 1.2 0.0 6.4 0.0 1.7 0.0 2.4 1.6 0.8 0.0 39.3 43.5 1.0 0.0 1.4 11.1 2.6 1.7 1.1 0.0 0.6 ANGPTL6 "AGF, ARP5" ENSG00000130812 "Angiopoietin like 6" Q8NI99 19 10092338-10102796 "Plasma proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 30.2" "Cell type enhanced" "Detected in some" "B-cells: 4.1;Hepatic stellate cells: 5.7;Hepatocytes: 8.2;Smooth muscle cells: 15.8;Spermatogonia: 6.3" "Cancer enhanced" "Detected in some" "testis cancer: 1.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "HMC-1: 58.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "Secreted to blood" NA NA 450000 23000000 "Cluster 24: B-cells - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "unprognostic (1.28e-1)" "unprognostic (2.18e-6)" "unprognostic (1.42e-2)" "unprognostic (1.54e-1)" "unprognostic (2.16e-1)" "unprognostic (1.02e-2)" "unprognostic (8.77e-2)" "unprognostic (5.25e-2)" "unprognostic (1.00e-1)" "unprognostic (2.99e-2)" "unprognostic (1.23e-2)" "unprognostic (1.85e-1)" "unprognostic (2.26e-10)" "unprognostic (8.96e-2)" "unprognostic (4.41e-2)" "unprognostic (1.25e-2)" "unprognostic (1.32e-1)" 0.3 0.3 0.8 2.1 0.7 2.8 0.3 0.8 1.1 0.2 0.4 0.6 0.7 0.1 0.2 0.3 0.7 0.4 0.2 0.7 0.8 0.5 30.2 0.5 3.3 1.7 1.1 0.3 1.1 0.1 0.4 2.2 1.3 0.2 0.4 0.1 0.2 0.0 0.0 0.3 3.5 0.2 1.2 3.4 1.6 1.6 1.0 0.8 0.3 0.0 3.3 0.5 0.2 1.7 0.3 0.0 0.0 0.1 0.1 0.0 0.4 0.2 0.1 0.0 0.2 0.0 0.1 7.8 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 2.0 0.2 0.2 0.0 0.5 58.9 0.0 0.2 0.1 0.1 0.3 0.0 0.6 0.4 0.3 0.0 0.0 1.3 4.7 0.2 0.4 1.1 0.2 0.0 0.2 0.0 0.0 0.1 0.2 0.3 0.0 0.5 0.0 0.0 5.0 0.0 0.1 0.1 0.0 0.0 5.1 1.4 2.9 0.2 0.7 0.7 0.0 0.3 0.0 0.6 0.4 0.4 0.7 0.4 0.4 0.1 0.9 0.2 0.4 0.0 0.4 0.2 0.1 0.5 0.2 0.8 0.7 0.8 1.1 0.7 0.8 1.7 1.1 1.3 1.2 1.0 1.7 0.3 0.0 0.0 0.0 4.1 0.3 0.1 0.4 0.0 0.1 0.4 0.3 0.4 2.8 0.3 0.0 0.0 0.2 1.7 0.1 1.9 0.3 0.3 0.0 0.3 0.2 0.0 0.4 0.9 0.0 0.2 2.5 0.5 0.1 0.0 0.1 5.7 8.2 2.3 0.0 0.6 0.0 0.0 0.0 0.3 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 2.1 0.0 0.2 0.5 0.2 0.2 0.0 0.1 15.8 0.5 6.3 0.0 0.0 0.3 1.0 0.9 0.1 0.1 ANKRD55 FLJ11795 ENSG00000164512 "Ankyrin repeat domain 55" Q3KP44 5 56099680-56233330 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 8.3;liver: 3.1;lymphoid tissue: 3.6;testis: 9.8" "Cell type enhanced" "Detected in some" "Early spermatids: 161.3;Hepatic stellate cells: 41.7;Inhibitory neurons: 103.5;Late spermatids: 29.1;Spermatocytes: 59.3" "Cancer enriched" "Detected in single" 6 "testis cancer: 1.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 22.9;eosinophil: 20.7;naive CD4 T-cell: 19.8" "Group enriched" "Detected in many" 74 "granulocytes: 22.9;T-cells: 19.8" "Group enriched" "Detected in some" 6 "HEL: 34.4;HMC-1: 17.1;NB-4: 22.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA051049, HPA061649" Uncertain Approved "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nuclear speckles" Cytosol "HPA051049: AB_2681326, HPA061649: " "unprognostic (1.00e-4)" "unprognostic (1.58e-4)" "unprognostic (2.63e-1)" "unprognostic (1.93e-1)" "unprognostic (7.78e-4)" "unprognostic (1.46e-3)" "unprognostic (1.47e-1)" "unprognostic (1.33e-2)" "unprognostic (1.47e-1)" "unprognostic (1.16e-1)" "unprognostic (1.33e-1)" "unprognostic (1.40e-1)" "unprognostic (7.19e-6)" "unprognostic (2.56e-2)" "unprognostic (1.48e-1)" "unprognostic (3.25e-2)" "unprognostic (1.01e-1)" 0.4 0.1 2.2 0.7 3.0 0.7 0.1 0.0 2.4 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.2 0.3 0.1 0.9 8.3 0.4 3.1 0.3 3.6 4.1 4.6 0.1 0.0 0.0 0.2 0.6 5.2 0.0 0.2 0.4 1.0 0.0 0.0 0.4 1.3 0.1 3.3 1.6 0.3 9.8 7.8 3.2 0.2 0.0 2.0 0.3 0.1 0.9 0.2 0.3 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.7 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 34.4 0.2 1.3 0.0 1.6 17.1 0.0 0.1 0.0 0.0 0.1 4.2 0.1 2.9 1.1 0.0 0.0 0.0 22.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 1.7 0.0 2.3 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 2.0 0.4 22.9 0.2 20.7 0.1 0.1 0.0 0.0 4.3 0.0 0.1 0.0 19.8 0.8 2.0 0.0 0.1 0.0 1.0 2.8 2.2 3.0 0.0 2.4 0.9 8.3 4.1 4.6 5.2 3.3 7.8 0.9 0.3 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.5 1.5 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 161.3 0.4 0.8 2.2 0.0 0.0 1.3 0.2 0.3 0.6 0.5 7.5 2.5 0.1 41.7 0.6 0.7 0.0 103.5 0.0 0.0 3.2 1.9 29.1 0.6 1.4 1.8 1.0 0.9 0.9 3.1 18.6 1.0 0.0 0.0 0.7 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.2 59.3 0.6 0.0 0.0 1.2 3.9 0.5 0.0 0.2 ANXA9 ANX31 ENSG00000143412 "Annexin A9" O76027 1 150982249-150995634 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 61.5;Collecting duct cells: 12.9;Ductal cells: 21.2;Hepatocytes: 17.4;Proximal tubular cells: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.6" "Group enriched" "Detected in many" 4 "dendritic cells: 1.6;granulocytes: 1.0;monocytes: 1.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 40.6;Hep G2: 42.3;MCF7: 59.2;OE19: 47.8;T-47d: 139.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA028404, HPA028698" Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles, Cytosol" "HPA028404: AB_10599190, HPA028698: AB_10600227" "unprognostic (4.06e-1)" "unprognostic (1.55e-2)" "unprognostic (3.15e-3)" "unprognostic (2.08e-3)" "unprognostic (2.93e-2)" "unprognostic (4.49e-2)" "unprognostic (1.84e-2)" "unprognostic (3.39e-2)" "unprognostic (1.08e-1)" "unprognostic (1.98e-1)" "unprognostic (2.10e-1)" "unprognostic (2.97e-1)" "prognostic favorable (8.74e-6)" "unprognostic (1.58e-2)" "unprognostic (1.11e-1)" "unprognostic (8.99e-2)" "unprognostic (1.72e-2)" 3.2 3.7 2.6 2.6 7.1 2.4 6.9 6.1 3.5 2.2 3.3 2.1 4.6 6.4 5.9 26.2 4.7 9.2 6.0 1.7 3.5 22.0 29.9 3.1 2.3 9.0 6.7 4.7 35.8 19.2 1.2 1.0 7.9 2.4 0.3 7.2 7.5 21.2 3.8 32.4 4.2 2.9 4.5 2.8 4.2 3.8 5.3 0.5 25.0 0.2 23.2 6.3 6.0 12.1 11.7 2.8 4.2 4.4 0.0 0.0 11.4 1.0 0.8 0.1 0.0 33.9 40.6 0.4 2.5 0.0 1.3 6.8 0.0 0.8 0.1 3.9 4.4 6.1 4.7 42.3 0.0 2.4 2.6 0.0 0.3 0.1 0.2 9.5 0.0 1.8 3.0 13.2 0.1 59.2 0.5 3.2 1.1 47.8 0.8 2.8 0.6 15.0 0.1 17.0 6.4 3.6 2.6 28.8 1.7 2.3 139.9 3.7 4.7 0.9 1.3 0.7 0.8 4.0 13.0 18.8 6.2 4.2 3.3 0.0 1.2 0.7 0.0 0.7 0.3 0.2 0.1 0.2 1.6 0.0 0.3 0.0 1.0 0.0 0.1 0.0 0.0 0.4 2.6 7.1 6.1 3.5 1.7 3.5 9.0 6.7 7.9 4.5 5.3 12.1 0.1 0.0 1.1 0.3 0.2 0.1 0.4 0.8 0.0 0.0 4.5 2.5 0.4 61.5 4.5 12.9 0.0 2.0 0.1 0.0 3.9 21.2 1.5 1.3 0.8 0.1 0.0 0.0 0.2 7.5 0.3 0.6 0.0 1.6 1.3 0.0 0.0 17.4 2.2 0.0 0.2 0.0 0.0 0.6 0.4 0.9 1.5 1.4 1.8 0.0 0.2 0.0 0.0 1.0 0.5 2.9 0.1 1.2 0.0 0.3 0.3 44.6 2.5 0.0 0.0 0.1 0.3 4.9 0.2 0.3 0.0 1.5 0.2 0.0 0.3 5.4 AOX1 "AO, AOH1" ENSG00000138356 "Aldehyde oxidase 1" Q06278 2 200586014-200677064 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adrenal gland: 300.5;liver: 891.0" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 749.1" "Cancer enriched" "Detected in many" 9 "liver cancer: 122.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 377.3;ASC TERT1: 191.5;HSkMC: 78.2;hTERT-HME1: 81.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA040199, HPA040215" Enhanced NA NA 3300000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "HPA040199: AB_10795273, HPA040215: AB_10795360" "unprognostic (4.39e-2)" "unprognostic (1.03e-3)" "unprognostic (1.96e-1)" "unprognostic (3.15e-2)" "unprognostic (1.17e-4)" "unprognostic (1.92e-2)" "unprognostic (2.34e-2)" "unprognostic (3.54e-1)" "unprognostic (1.15e-1)" "unprognostic (4.93e-2)" "unprognostic (5.48e-2)" "unprognostic (2.00e-2)" "prognostic favorable (6.05e-5)" "unprognostic (1.33e-2)" "unprognostic (8.16e-3)" "unprognostic (3.38e-2)" "unprognostic (4.99e-3)" 87.6 300.5 0.6 3.2 2.9 0.5 50.2 0.1 2.4 17.9 3.6 12.0 0.8 10.8 12.3 8.2 48.2 9.9 14.9 1.1 1.5 103.2 891.0 19.5 4.7 1.3 1.0 48.0 85.0 1.3 2.8 1.7 1.2 22.3 4.5 0.5 15.3 28.3 12.9 20.1 12.7 7.1 0.5 4.1 14.3 19.4 4.0 2.0 17.7 11.0 1.5 38.6 17.7 3.6 0.6 0.2 0.0 0.0 377.3 191.5 0.2 6.6 12.2 5.4 9.7 0.0 0.1 0.1 0.5 8.4 2.3 0.2 0.1 18.6 22.0 0.2 0.6 0.0 4.6 20.7 25.4 0.9 0.0 78.2 4.6 26.1 81.2 5.4 0.2 0.2 0.2 0.1 18.3 0.5 0.0 0.1 8.0 0.1 5.2 0.0 0.5 0.1 0.2 0.2 0.4 0.3 4.8 0.0 0.3 0.4 0.1 0.2 31.9 13.8 11.2 0.2 2.5 0.2 0.1 2.6 10.7 0.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.9 0.1 2.4 1.1 1.5 1.3 1.0 1.2 0.5 4.0 3.6 1.0 3.2 1.1 0.7 3.6 1.8 0.5 1.2 1.2 0.1 0.2 0.3 0.9 17.2 0.1 3.7 0.0 0.1 0.0 0.1 11.7 0.7 0.8 0.4 3.0 2.6 3.0 37.5 0.9 26.2 0.2 22.9 0.0 8.2 0.0 0.1 15.4 749.1 0.4 0.0 2.5 0.1 2.0 19.8 3.6 4.4 74.0 1.7 3.6 1.0 0.0 0.6 0.0 5.0 6.9 11.5 0.0 82.0 0.0 7.5 0.1 162.2 0.1 0.1 0.0 5.3 3.0 0.8 1.3 0.1 1.6 0.0 2.0 2.3 0.1 0.4 APCS "MGC88159, PTX2, SAP" ENSG00000132703 "Amyloid P component, serum" P02743 1 159587826-159588865 "Disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 76 "liver: 3629.2" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 4141.9" "Cancer enriched" "Detected in some" 25 "liver cancer: 826.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RH-30: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB007817, HPA053294" Supported "Secreted to blood" NA NA 27700000000 39000000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 2: Hepatocytes - Metabolism" "CAB007817: AB_598185, HPA053294: AB_2682104" "unprognostic (3.19e-3)" "unprognostic (2.30e-2)" 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 47.7 0.2 0.0 0.0 1.3 3629.2 0.1 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 388.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 198.8 0.0 0.0 0.0 2.7 0.0 45.5 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 57.8 4141.9 0.0 0.0 0.0 0.0 0.0 88.9 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 APOB ENSG00000084674 "Apolipoprotein B" P04114 2 21001429-21044073 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Atherosclerosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 143 "intestine: 304.3;liver: 1191.0" "Group enriched" "Detected in some" 8 "Hepatocytes: 2967.4;Proximal enterocytes: 1585.9" "Cancer enriched" "Detected in some" 99 "liver cancer: 295.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 30 "Hep G2: 1079.8" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016070, HPA049793" Supported Supported Vesicles,Cytosol "Secreted to blood" NA NA 1490000000000 100000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Vesicles, Cytosol" "CAB016070: AB_626690, HPA049793: AB_2680885" "unprognostic (1.63e-2)" "unprognostic (2.71e-2)" "unprognostic (1.75e-1)" "unprognostic (1.06e-1)" "unprognostic (1.04e-2)" "unprognostic (7.31e-2)" "unprognostic (1.46e-2)" "unprognostic (6.53e-3)" "unprognostic (4.43e-2)" "unprognostic (8.89e-3)" "unprognostic (3.01e-1)" "unprognostic (4.59e-3)" "unprognostic (3.60e-3)" "unprognostic (2.89e-2)" "unprognostic (2.38e-1)" "unprognostic (2.99e-1)" "unprognostic (6.23e-2)" 2.7 0.0 0.1 0.2 0.2 0.1 0.9 0.1 0.1 0.7 0.2 0.4 181.4 0.2 0.0 0.1 0.1 0.5 5.2 0.1 0.3 0.3 1191.0 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.3 0.2 0.1 0.0 0.0 0.1 0.1 0.5 304.3 0.2 0.2 0.5 0.3 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.0 35.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 1079.8 0.0 0.6 0.1 0.8 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.5 0.6 0.0 0.6 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.3 0.2 0.2 0.3 0.2 0.2 0.3 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 277.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 1.6 3.5 0.0 104.2 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.1 52.8 2967.4 0.1 0.0 0.2 30.8 0.0 69.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 32.5 1.5 0.0 0.0 1585.9 0.6 0.0 0.0 0.0 1.1 0.2 0.5 0.3 0.0 0.0 0.0 3.9 0.9 14.5 0.0 APOBEC3A "ARP3, PHRBN" ENSG00000128383 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3A" P31941 22 38952741-38992778 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 93.9;lymphoid tissue: 48.3;urinary bladder: 24.4" "Cell type enriched" "Detected in many" 4 "Urothelial cells: 426.0" "Group enriched" "Detected in many" 4 "cervical cancer: 11.3;head and neck cancer: 15.8" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 1014.5" "Lineage enriched" "Detected in many" 8 "monocytes: 1014.5" "Not detected" "Not detected" "HPA043237, HPA056980, HPA066719" Approved Uncertain Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "HPA043237: AB_10795980, HPA056980: AB_2683298, HPA066719: AB_2685711" "unprognostic (6.45e-3)" "unprognostic (1.44e-2)" "unprognostic (1.12e-1)" "unprognostic (5.21e-3)" "unprognostic (1.31e-1)" "unprognostic (2.72e-2)" "unprognostic (1.91e-1)" "unprognostic (1.91e-1)" "unprognostic (3.52e-1)" "unprognostic (2.59e-3)" "unprognostic (9.01e-3)" "unprognostic (2.00e-1)" "unprognostic (1.13e-2)" "unprognostic (1.76e-1)" "unprognostic (4.98e-2)" "unprognostic (3.41e-1)" "unprognostic (1.91e-1)" 7.9 0.4 0.5 20.9 0.5 93.9 0.8 0.7 1.1 2.2 0.8 1.5 1.4 0.4 0.3 12.2 4.2 6.3 1.4 0.9 0.5 0.7 2.0 13.4 1.1 0.6 0.4 0.2 1.5 0.4 0.3 3.5 0.7 0.4 0.6 0.2 6.7 0.3 0.5 0.6 0.8 1.7 0.3 48.3 1.1 0.2 0.5 2.4 1.0 3.7 21.1 24.4 10.3 1.0 0.1 0.0 0.1 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.5 0.1 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.4 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.3 0.6 0.3 34.7 223.9 8.4 0.7 1014.5 1.5 3.1 0.6 0.7 10.4 0.8 0.7 0.7 121.7 0.9 298.5 1.3 1.0 149.1 0.5 0.5 0.7 1.1 0.9 0.5 0.6 0.4 0.7 0.3 0.5 1.0 0.7 28.9 33.6 0.0 0.5 1.3 16.0 1.8 0.0 0.6 0.7 0.3 0.1 0.0 24.1 1.8 4.2 0.3 0.2 17.5 0.0 0.1 0.6 0.5 0.2 1.4 0.0 8.0 0.0 0.2 0.3 6.3 0.0 0.6 25.9 0.3 0.7 0.4 14.9 0.0 0.0 0.0 2.0 18.8 41.4 0.1 0.3 91.3 16.0 0.0 17.9 0.8 2.1 0.0 0.0 1.3 27.4 0.4 15.6 6.7 4.5 0.2 10.7 0.8 0.0 1.0 1.2 0.1 0.4 48.7 6.8 0.3 3.1 0.2 1.7 426.0 APOE AD2 ENSG00000130203 "Apolipoprotein E" P02649 19 44905791-44909393 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Hyperlipidemia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adrenal gland: 3453.9;liver: 6592.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 9363.4;Hofbauer cells: 6072.6;Muller glia cells: 9454.8;Peritubular cells: 4958.2;Proximal tubular cells: 8155.9;Theca cells: 7201.0" "Cancer enhanced" "Detected in all" "liver cancer: 3183.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1867.0;CACO-2: 466.1;Hep G2: 935.3;HSkMC: 1374.2;SK-MEL-30: 1956.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008363, HPA065539, HPA068768, CAB069921" Enhanced Approved Vesicles "Secreted to blood" NA NA 51800000000 29000000000 "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB008363: AB_590560, CAB069921: AB_920623, HPA065539: AB_2685509, HPA068768: AB_2686029" "unprognostic (8.98e-2)" "unprognostic (2.32e-2)" "unprognostic (2.49e-2)" "unprognostic (5.28e-2)" "unprognostic (3.77e-2)" "unprognostic (7.25e-2)" "unprognostic (5.22e-3)" "unprognostic (6.13e-2)" "unprognostic (5.06e-2)" "unprognostic (4.13e-1)" "unprognostic (5.78e-2)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (7.76e-2)" "unprognostic (1.64e-1)" "unprognostic (1.12e-3)" "unprognostic (4.13e-2)" 522.1 3453.9 813.4 92.8 1164.2 66.5 325.1 775.0 943.2 271.2 329.2 130.9 40.3 81.5 20.0 37.2 72.2 100.2 176.3 606.1 841.6 1066.0 6592.5 258.8 352.2 1016.0 1037.0 508.2 41.9 34.5 110.9 102.2 1106.9 45.4 22.9 87.6 80.5 10.8 31.1 381.2 165.9 12.6 823.2 620.3 83.3 140.5 962.6 57.8 146.4 10.4 46.1 93.4 135.5 964.4 3.2 5.2 9.5 2.6 1867.0 76.3 69.4 1.5 4.3 8.4 1.4 466.1 2.8 2.0 9.9 0.3 9.1 6.4 12.6 2.1 0.7 1.7 4.0 3.3 1.7 935.3 192.4 6.8 2.3 1374.2 2.5 14.8 1.3 15.6 1.0 0.7 124.9 2.8 1.2 3.3 1.9 2.5 243.2 3.0 1.3 2.6 8.0 1.8 2.8 0.9 5.6 2.4 4.5 1.4 1956.0 131.6 165.3 52.8 3.3 13.2 3.1 1.4 1.6 5.9 8.6 3.8 5.9 4.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 813.4 1164.2 775.0 943.2 606.1 841.6 1016.0 1037.0 1106.9 823.2 962.6 964.4 136.7 0.0 8.2 444.0 66.1 935.2 12.3 18.3 67.7 81.7 86.7 565.8 2.2 450.4 5.2 228.1 41.7 46.3 6.0 2.2 682.9 1.8 73.6 33.8 936.6 140.2 0.0 331.6 1.1 0.7 43.8 860.7 3.6 22.9 174.4 103.6 208.9 9363.4 6072.6 38.7 2.1 0.6 4.1 718.0 292.6 355.3 2629.4 940.6 2481.3 60.9 70.3 9454.8 0.0 12.1 2.2 0.6 0.3 4958.2 7.2 15.0 0.2 8155.9 1.0 311.4 223.5 2958.4 345.5 14.8 12.8 15.1 1684.9 74.3 60.6 7201.0 1.7 4.7 APOH "B2G1, BG" ENSG00000091583 "Apolipoprotein H" P02749 17 66212033-66256525 "Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 563 "liver: 17965.3" "Cell type enriched" "Detected in some" 41 "Hepatocytes: 7680.6" "Cancer enriched" "Detected in many" 232 "liver cancer: 2878.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 21 "Hep G2: 1253.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA001654, HPA003732, CAB022214" Enhanced Supported "Golgi apparatus" "Secreted to blood" NA NA 247000000000 41000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "CAB022214: , HPA001654: AB_1078181, HPA003732: AB_1078183" "unprognostic (2.11e-2)" "unprognostic (1.87e-1)" "unprognostic (1.28e-1)" "prognostic favorable (2.39e-7)" "unprognostic (1.26e-1)" "unprognostic (5.99e-2)" "unprognostic (2.88e-3)" "prognostic unfavorable (1.10e-6)" "unprognostic (1.26e-2)" "unprognostic (5.76e-2)" 0.9 0.3 0.0 0.1 0.1 0.4 0.2 0.1 0.2 0.2 0.3 0.8 2.5 0.1 1.0 0.2 0.8 2.8 0.6 0.2 0.0 31.9 17965.3 5.6 0.3 0.2 0.1 0.2 10.9 0.0 0.2 0.4 0.1 0.2 0.7 0.2 0.1 0.3 0.1 0.2 1.0 0.0 0.1 4.3 3.8 0.3 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.2 0.0 33.5 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 60.8 0.0 1.4 0.1 0.0 1.7 1.1 0.0 0.0 0.0 0.4 0.0 2.6 1.4 1253.3 0.0 6.4 0.7 0.0 0.0 0.1 0.0 0.1 0.0 0.1 1.4 0.5 0.2 0.0 0.2 0.1 0.6 31.5 0.0 0.8 6.4 0.1 0.0 0.9 0.4 0.0 3.4 0.1 0.2 0.0 0.0 0.0 1.7 0.2 0.1 0.1 0.0 0.8 0.1 2.9 15.3 2.4 0.2 0.2 0.2 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.0 12.3 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 183.0 0.6 0.0 0.0 0.0 0.0 0.2 3.9 0.8 0.2 0.2 0.0 5.2 0.0 109.7 0.2 2.3 0.6 0.0 0.0 0.1 0.0 0.0 120.0 7680.6 0.5 0.0 0.2 0.4 0.0 182.4 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.2 0.8 0.0 0.0 0.0 0.4 25.6 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 8.8 0.0 0.8 0.0 AR "AIS, DHTR, HUMARA, NR3C4, SBMA, SMAX1" ENSG00000169083 "Androgen receptor" P10275 X 67544021-67730619 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 38.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 93.7;Granulosa cells: 104.8;Hepatocytes: 269.2;Leydig cells: 77.9;Peritubular cells: 86.5;Skeletal myocytes: 75.0" "Cancer enhanced" "Detected in many" "breast cancer: 15.6;prostate cancer: 16.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 13.3;BJ hTERT+: 10.3;HAP1: 14.9;LHCN-M2: 16.1;RH-30: 23.6;T-47d: 10.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000001, HPA004733, CAB065764" Enhanced Supported Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 35: Glandular cells - Unknown function" Cytosol "CAB000001: AB_2060174, CAB065764: AB_10620739, HPA004733: " "unprognostic (1.34e-1)" "unprognostic (8.10e-3)" "unprognostic (2.49e-2)" "unprognostic (5.95e-2)" "unprognostic (1.04e-2)" "unprognostic (3.35e-2)" "prognostic favorable (8.77e-4)" "unprognostic (4.99e-2)" "unprognostic (1.72e-1)" "unprognostic (7.79e-2)" "unprognostic (2.30e-1)" "unprognostic (2.29e-1)" "prognostic favorable (1.03e-8)" "unprognostic (8.23e-3)" "unprognostic (8.90e-2)" "unprognostic (4.23e-2)" "unprognostic (7.97e-2)" 6.7 1.0 1.1 0.5 1.3 0.0 8.7 1.7 1.1 23.6 0.2 2.0 0.2 18.6 16.1 1.2 20.7 2.0 5.8 1.0 3.5 3.6 38.2 1.5 0.3 3.5 2.6 14.6 0.8 0.1 1.9 0.1 2.7 16.5 0.6 0.2 1.4 18.2 13.9 5.2 0.9 9.5 2.1 1.3 1.5 3.9 4.8 2.7 2.1 6.1 0.5 3.5 12.9 2.0 0.0 4.8 13.3 0.0 0.0 0.0 0.0 7.3 10.3 0.3 0.1 0.1 0.0 0.0 0.0 1.0 0.0 0.0 14.9 0.0 0.0 0.0 2.4 0.0 1.5 0.0 0.8 0.0 0.0 5.5 0.0 1.8 0.0 0.0 3.9 0.1 4.6 2.2 16.1 1.5 0.0 0.0 5.4 0.0 0.0 0.0 23.6 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.0 3.6 10.9 7.6 0.3 0.3 2.2 0.0 3.5 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.3 1.7 1.1 1.0 3.5 3.5 2.6 2.7 2.1 4.8 2.0 3.1 0.0 5.0 28.4 0.4 9.7 17.8 0.2 15.9 0.7 93.7 33.7 37.4 14.3 10.7 3.7 0.0 3.5 14.0 0.0 1.9 11.3 1.1 2.9 49.1 10.5 0.0 5.3 7.7 0.0 0.2 39.4 0.0 5.8 1.3 104.8 36.0 269.2 0.8 0.0 17.8 0.3 0.0 2.2 4.2 4.4 77.9 3.3 10.6 1.0 1.7 0.2 0.0 26.7 0.2 0.6 0.0 86.5 0.0 36.5 0.6 27.7 3.6 0.3 65.7 75.0 20.8 0.8 3.3 12.7 16.1 1.0 1.7 37.8 0.2 22.0 ARHGAP15 BM046 ENSG00000075884 "Rho GTPase activating protein 15" Q53QZ3 2 143091362-143768352 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 79.8;lymphoid tissue: 75.2" "Cell type enhanced" "Detected in many" "B-cells: 126.3;Early spermatids: 132.3;granulocytes: 88.5;Microglial cells: 250.1;NK-cells: 89.6;T-cells: 149.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 59.4;HEL: 75.8;HL-60: 124.3;MOLT-4: 82.0;NB-4: 100.4;THP-1: 131.0;U-698: 89.5;U-937: 63.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032125 Uncertain "Nucleoplasm,Golgi apparatus,Vesicles" NA NA 38000 "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "Golgi apparatus, Vesicles" Nucleoplasm "HPA032125: AB_10671370" "unprognostic (1.59e-2)" "unprognostic (2.40e-3)" "unprognostic (8.63e-2)" "unprognostic (2.19e-2)" "unprognostic (2.99e-1)" "unprognostic (6.62e-3)" "unprognostic (6.14e-2)" "unprognostic (2.18e-3)" "unprognostic (1.32e-2)" "unprognostic (3.58e-2)" "unprognostic (2.13e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (6.95e-5)" "unprognostic (4.40e-2)" "unprognostic (2.12e-2)" "unprognostic (4.58e-2)" "unprognostic (6.94e-2)" 6.9 5.9 1.4 27.1 1.3 79.8 7.6 2.3 2.3 4.1 1.9 7.3 6.8 2.6 9.7 4.0 2.8 11.4 5.6 1.2 2.2 4.4 10.2 9.8 59.3 3.0 1.9 1.8 1.3 1.7 1.0 4.0 2.7 4.3 7.7 1.3 4.2 5.1 1.2 2.0 15.1 3.9 1.9 44.9 7.5 7.4 2.1 75.2 4.5 2.2 46.3 11.4 4.3 4.0 0.3 0.1 4.9 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 59.4 0.2 0.1 0.1 0.1 0.2 0.1 0.3 14.6 0.0 75.8 0.5 0.1 0.0 124.3 1.2 0.0 0.0 0.2 0.2 0.1 0.0 47.0 0.3 4.4 0.0 0.1 82.0 100.4 0.3 0.0 0.1 44.7 0.6 22.7 0.0 0.1 0.2 0.4 0.3 0.2 1.0 0.1 4.5 131.0 0.6 0.4 1.2 0.1 0.2 1.0 0.3 89.5 0.7 63.9 3.9 181.8 32.0 140.1 97.7 34.3 161.6 94.3 172.8 125.7 56.3 86.2 119.0 101.7 207.2 121.4 40.5 54.3 147.7 99.9 1.4 1.3 2.3 2.3 1.2 2.2 3.0 1.9 2.7 1.9 2.1 4.0 8.2 0.0 9.6 2.0 126.3 5.6 0.1 0.0 0.0 0.3 1.8 2.0 3.9 1.5 2.5 0.0 0.0 0.2 78.9 0.3 0.0 0.1 132.3 1.8 2.3 4.3 0.0 26.3 12.2 0.0 0.3 9.7 8.6 3.5 88.5 0.0 8.6 0.8 21.3 1.7 6.8 0.0 0.0 39.9 30.9 17.5 14.9 43.0 8.8 250.1 34.9 0.4 89.6 20.6 3.2 0.0 0.0 3.4 65.8 0.2 0.0 0.7 2.2 0.3 46.0 2.7 31.6 68.4 1.2 0.4 4.5 0.3 149.2 0.1 0.2 0.2 ARHGAP23 KIAA1501 ENSG00000275832 "Rho GTPase activating protein 23" Q9P227 17 38419280-38512385 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 97.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 59.4;Hepatic stellate cells: 46.1;Oligodendrocytes: 129.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 296.7;RT4: 115.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019818, HPA047291" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" Cytosol "HPA019818: AB_1844993, HPA047291: AB_2680012" "unprognostic (3.35e-1)" "unprognostic (5.11e-2)" "unprognostic (6.43e-2)" "prognostic unfavorable (6.87e-5)" "unprognostic (9.53e-2)" "unprognostic (1.46e-1)" "unprognostic (1.80e-1)" "unprognostic (1.99e-1)" "unprognostic (5.56e-2)" "unprognostic (1.50e-3)" "prognostic unfavorable (3.24e-4)" "unprognostic (3.67e-2)" "prognostic unfavorable (5.38e-5)" "unprognostic (8.36e-2)" "unprognostic (5.83e-2)" "unprognostic (4.57e-2)" "unprognostic (2.25e-1)" 25.6 13.8 36.2 8.3 66.2 10.7 18.8 47.2 54.6 25.9 5.5 22.8 3.0 28.4 3.7 60.8 18.4 7.8 27.3 34.4 37.5 11.8 2.9 28.0 4.1 63.7 59.6 18.1 3.5 3.1 6.2 19.4 54.1 19.9 2.8 8.5 12.8 12.5 10.6 61.1 10.4 11.6 43.0 30.7 13.4 16.1 66.1 5.4 9.5 5.8 11.0 36.3 29.5 97.8 32.5 17.2 15.2 5.1 9.5 31.1 19.6 44.8 49.5 37.7 21.8 56.8 55.1 0.7 35.2 102.5 18.7 296.7 1.7 62.3 26.6 3.5 3.3 0.0 55.1 0.4 47.2 3.0 0.3 18.8 11.8 27.7 17.3 31.0 39.4 6.0 0.6 8.3 21.6 0.0 10.2 6.3 9.0 1.2 6.3 17.0 33.0 10.4 16.0 115.7 3.7 8.8 26.9 0.1 0.3 21.2 6.7 7.9 57.7 62.6 22.9 12.9 12.1 6.5 7.3 1.9 16.3 8.1 56.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.2 66.2 47.2 54.6 34.4 37.5 63.7 59.6 54.1 43.0 66.1 97.8 27.2 12.8 1.5 23.8 0.7 9.9 17.5 10.6 9.1 59.4 1.7 3.9 20.4 1.5 13.2 3.7 0.0 27.0 0.2 0.1 0.0 2.9 7.6 8.5 10.0 34.9 0.0 4.0 9.3 1.4 3.1 11.6 3.1 5.7 0.0 4.9 46.1 0.5 5.1 26.9 16.2 0.4 2.0 2.5 4.2 21.0 9.0 1.2 1.8 9.4 0.2 9.6 0.0 20.1 129.2 7.0 0.1 7.2 1.7 15.4 0.0 0.2 8.3 3.4 0.0 10.9 7.6 13.5 2.7 27.5 25.9 16.6 1.8 1.3 0.3 42.2 ARHGEF25 "GEFT, p63RhoGEF" ENSG00000240771 "Rho guanine nucleotide exchange factor 25" Q86VW2 12 57610180-57617245 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 151.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 20.8;Leydig cells: 24.8;Peritubular cells: 45.9;Sertoli cells: 26.3;Smooth muscle cells: 38.9" "Cancer enhanced" "Detected in all" "glioma: 23.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 59.1;RH-30: 129.7;SH-SY5Y: 58.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052016 Approved NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" "HPA052016: AB_2681695" "unprognostic (8.43e-2)" "unprognostic (4.24e-3)" "unprognostic (2.13e-3)" "unprognostic (6.95e-3)" "unprognostic (8.12e-2)" "unprognostic (1.99e-2)" "unprognostic (1.38e-1)" "unprognostic (9.18e-2)" "unprognostic (2.45e-2)" "unprognostic (2.39e-2)" "unprognostic (4.63e-3)" "unprognostic (2.51e-1)" "prognostic unfavorable (4.20e-7)" "unprognostic (1.41e-2)" "unprognostic (2.03e-1)" "unprognostic (6.82e-3)" "unprognostic (3.22e-3)" 34.4 12.0 30.7 10.7 38.7 0.1 29.1 38.5 72.1 64.5 12.6 151.2 10.3 92.8 44.3 29.6 85.5 23.6 24.6 72.0 21.7 17.7 5.0 21.7 6.2 20.6 21.1 58.2 8.5 9.4 26.4 9.4 20.8 60.6 19.5 13.2 13.9 80.4 11.4 12.0 34.4 68.8 17.3 20.1 45.0 10.6 22.5 2.1 14.1 13.8 4.9 84.3 51.4 40.5 0.8 8.9 41.6 26.1 0.1 0.0 3.3 12.7 37.4 16.5 20.2 5.2 8.1 3.5 10.7 23.4 7.7 0.4 16.2 0.7 13.9 11.7 13.9 7.4 6.1 11.4 11.6 0.2 19.2 11.5 3.5 7.5 1.1 59.1 6.5 2.0 15.5 16.0 12.2 3.0 2.7 0.3 26.5 0.4 0.4 0.0 129.7 0.7 0.7 0.7 24.1 58.7 2.4 1.2 4.8 14.8 4.3 8.9 0.0 14.8 14.0 9.7 4.7 33.5 5.4 0.1 12.4 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.7 38.7 38.5 72.1 72.0 21.7 20.6 21.1 20.8 17.3 22.5 40.5 5.6 0.0 0.0 8.5 0.0 2.0 1.8 0.2 4.6 17.7 1.8 8.6 11.6 0.0 0.6 0.0 2.1 0.2 0.6 0.0 0.0 0.5 0.2 1.1 20.8 4.4 0.0 0.0 15.3 1.4 0.5 12.6 0.5 0.6 0.0 2.6 6.8 0.0 0.5 8.4 8.5 0.0 0.0 0.0 1.7 1.5 24.8 0.2 0.0 8.4 0.0 5.4 2.1 3.0 1.6 0.3 0.0 45.9 0.3 0.8 0.0 0.4 0.0 2.8 26.3 6.3 38.9 1.4 1.4 0.9 1.1 0.3 0.5 9.6 0.0 0.4 ARL6IP1 "AIP1, ARL6IP, ARMER, KIAA0069, SPG61" ENSG00000170540 "ADP ribosylation factor like GTPase 6 interacting protein 1" Q15041 16 18791669-18801572 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045307 Uncertain Approved "Endoplasmic reticulum" NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 12: Non-specific - Cell cycle regulation" "Endoplasmic reticulum" "HPA045307: AB_10961042" "unprognostic (2.42e-1)" "unprognostic (3.47e-2)" "unprognostic (4.07e-3)" "unprognostic (1.12e-1)" "unprognostic (1.54e-1)" "unprognostic (2.60e-3)" "unprognostic (2.58e-2)" "unprognostic (1.76e-2)" "unprognostic (3.88e-2)" "unprognostic (6.83e-2)" "unprognostic (1.91e-3)" "unprognostic (3.33e-2)" "unprognostic (1.13e-2)" "unprognostic (7.09e-2)" "unprognostic (4.60e-2)" "unprognostic (6.32e-3)" "unprognostic (5.36e-3)" 142.0 171.3 206.4 77.7 217.3 209.7 112.9 200.6 282.2 79.2 182.4 140.9 138.8 70.8 122.9 70.0 86.6 131.9 32.1 227.7 209.2 150.1 359.6 79.6 132.6 192.0 197.8 101.6 81.7 180.6 40.7 90.3 200.0 75.9 123.4 316.0 84.3 70.4 23.1 66.1 123.4 69.1 185.0 72.8 125.8 129.9 200.5 158.5 112.5 51.5 113.4 132.5 47.4 197.6 375.3 334.6 417.8 331.6 146.7 93.5 373.2 208.9 196.9 311.0 246.7 205.7 851.1 315.7 388.4 198.0 209.2 388.9 303.7 144.2 359.1 421.2 137.1 227.9 192.5 549.1 116.4 329.9 232.0 78.6 137.7 216.2 224.0 229.1 316.1 180.5 251.0 318.5 607.6 331.4 229.9 238.3 520.0 311.7 109.8 387.9 535.9 266.0 337.8 206.1 255.2 287.5 466.5 279.8 204.5 280.1 576.1 315.9 189.2 204.2 192.9 147.1 384.1 109.5 209.5 383.2 182.8 215.6 405.5 211.4 125.2 84.2 179.4 119.5 167.0 163.2 159.0 199.1 127.4 160.7 137.9 166.4 105.9 179.2 133.3 221.6 281.5 295.0 206.4 217.3 200.6 282.2 227.7 209.2 192.0 197.8 200.0 185.0 200.5 197.6 306.4 67.3 51.0 56.8 170.6 372.6 241.4 170.1 309.6 189.2 256.5 216.8 30.6 361.8 128.7 286.9 131.3 296.7 164.6 269.0 174.1 398.2 74.6 93.3 61.7 188.1 145.9 503.8 70.4 203.1 385.4 150.4 257.9 158.3 135.8 198.0 275.5 457.4 253.9 89.2 94.2 234.6 229.9 275.8 424.6 42.7 84.8 205.8 200.9 39.4 267.3 318.5 142.2 57.3 50.3 271.0 288.5 110.9 107.5 219.4 217.0 189.1 126.6 218.0 92.1 125.6 118.6 193.6 56.6 295.2 326.5 326.6 186.9 53.1 319.7 323.8 ARSD ENSG00000006756 "Arylsulfatase D" P51689 X 2903972-2929349 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 109.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 23.2;EFO-21: 24.5" "HPA004694, HPA063835" Approved Approved "Vesicles,Lipid droplets" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Lipid droplets" "HPA004694: AB_1078221, HPA063835: AB_2685132" "unprognostic (3.92e-1)" "unprognostic (7.50e-2)" "unprognostic (3.33e-1)" "prognostic favorable (5.21e-4)" "unprognostic (5.90e-3)" "unprognostic (6.32e-3)" "unprognostic (1.73e-1)" "unprognostic (1.34e-1)" "unprognostic (2.44e-1)" "unprognostic (4.09e-3)" "unprognostic (7.18e-2)" "unprognostic (3.93e-1)" "prognostic favorable (1.97e-5)" "unprognostic (1.37e-1)" "unprognostic (3.93e-2)" "unprognostic (4.99e-2)" "unprognostic (2.11e-3)" 8.4 7.8 4.3 6.1 4.1 4.9 23.6 4.2 4.5 23.9 10.7 20.5 21.0 11.2 15.9 10.0 28.0 11.4 4.8 4.1 5.1 38.9 40.0 16.8 3.6 6.3 5.7 18.7 32.4 12.7 4.2 8.6 5.4 19.3 14.8 1.7 17.5 13.3 1.7 7.3 15.4 7.6 5.6 7.2 30.4 3.8 4.6 2.8 21.1 3.2 4.2 11.7 8.4 5.0 6.9 12.0 3.2 15.4 13.6 7.7 0.1 3.9 7.1 1.7 1.1 0.7 23.2 0.0 24.5 7.9 18.1 0.0 0.6 2.0 1.6 0.2 0.0 0.0 0.0 4.0 7.5 0.0 9.1 12.3 6.3 3.4 3.6 11.1 11.5 0.0 0.0 0.1 7.6 16.9 0.1 1.7 2.7 21.3 5.0 2.9 0.0 0.2 12.3 0.1 0.0 8.5 5.4 6.3 4.1 8.5 17.1 13.1 10.6 0.0 0.5 1.2 1.8 0.1 0.0 0.0 11.1 8.2 8.8 1.5 5.8 4.1 1.7 5.0 0.6 1.3 0.8 1.4 4.4 0.8 0.2 0.9 1.0 2.0 2.0 3.0 0.3 2.5 4.3 4.1 4.2 4.5 4.1 5.1 6.3 5.7 5.4 5.6 4.6 5.0 13.4 19.2 36.4 9.8 4.5 5.0 13.9 11.3 10.8 4.9 45.0 30.9 5.6 74.4 23.1 44.1 0.0 19.1 8.6 44.3 19.6 35.1 0.7 68.6 19.6 13.8 67.9 3.4 0.9 53.9 25.0 7.9 31.6 67.8 16.5 66.8 11.7 109.9 18.5 0.0 1.7 56.2 10.2 17.8 6.4 1.4 6.2 16.1 14.2 6.5 23.1 5.8 11.3 3.5 1.5 47.4 47.9 6.8 1.6 18.1 53.1 23.4 25.8 0.9 6.6 15.1 10.7 1.3 3.9 16.2 7.2 26.0 4.3 38.3 60.9 16.4 ART4 "ARTC4, CD297, DO, DOK1" ENSG00000111339 "ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)" Q93070 12 14825569-14843526 "Blood group antigen proteins, CD markers, Enzymes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 53.3;lymphoid tissue: 19.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 15.7;Endothelial cells: 12.9;Erythroid cells: 51.3;Hepatic stellate cells: 66.0;Hepatocytes: 30.2" "Group enriched" "Detected in some" 5 "liver cancer: 3.8;pancreatic cancer: 1.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 6.0;HEL: 12.1;Hep G2: 7.3;HUVEC TERT2: 27.0" "Region enhanced" "Detected in single" "olfactory bulb: 1.8" "Low region specificity" "Detected in all" HPA075664 Approved "Rods & Rings" "Secreted to blood" NA NA 17000000 "Cluster 85: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 6: Erythroid cells - Oxygen transport" "Rods & Rings" "HPA075664: " "unprognostic (2.50e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-1)" "unprognostic (1.18e-2)" "unprognostic (1.55e-1)" "unprognostic (1.37e-2)" "unprognostic (1.92e-1)" "unprognostic (1.90e-2)" "unprognostic (1.10e-1)" "unprognostic (2.64e-1)" "unprognostic (1.37e-1)" "unprognostic (1.90e-2)" "unprognostic (2.62e-3)" "unprognostic (4.33e-3)" "unprognostic (1.25e-3)" "unprognostic (1.05e-1)" "unprognostic (1.71e-1)" 2.6 2.7 0.3 1.1 0.5 4.6 1.8 0.1 0.4 0.9 0.4 0.6 0.0 0.8 0.3 0.9 2.1 9.0 9.0 0.3 1.1 3.6 53.3 3.2 8.6 0.5 0.4 0.5 2.3 0.3 0.1 7.0 0.4 0.3 0.5 0.3 0.7 0.4 0.3 0.3 0.6 1.1 0.2 19.0 0.3 0.2 0.4 1.9 3.6 0.2 2.3 0.6 0.5 0.6 0.0 0.0 0.2 6.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 7.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.6 0.2 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.1 0.4 0.3 1.1 0.5 0.4 0.4 0.2 0.4 0.6 0.7 0.0 1.1 0.7 0.2 0.3 0.8 0.0 0.0 2.4 0.2 0.1 1.5 15.7 0.0 1.8 12.5 0.9 0.1 0.0 0.0 0.9 0.4 0.2 0.1 12.9 0.0 51.3 0.2 1.9 2.5 1.9 0.0 0.1 0.0 0.0 66.0 30.2 0.1 0.0 0.2 0.0 0.0 4.7 1.3 0.3 1.8 0.1 1.8 0.0 0.0 0.3 1.0 0.0 0.3 0.6 0.0 0.0 0.0 0.2 0.0 0.2 0.0 11.8 6.6 0.5 1.2 0.1 0.1 0.0 0.1 0.3 0.2 0.0 0.0 0.4 ASGR2 CLEC4H2 ENSG00000161944 "Asialoglycoprotein receptor 2" P07307 17 7101322-7115700 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "liver: 840.7" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 878.6" "Cancer enriched" "Detected in many" 66 "liver cancer: 214.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "classical monocyte: 110.0;myeloid DC: 64.1" "Group enriched" "Detected in many" 51 "dendritic cells: 64.1;monocytes: 110.0" "Cell line enriched" "Detected in some" 9 "Hep G2: 528.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA014899, HPA015998" Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA 14000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum, Plasma membrane" "HPA014899: AB_1845085, HPA015998: AB_1845084" "unprognostic (6.76e-2)" "unprognostic (7.45e-7)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" "unprognostic (1.03e-2)" "unprognostic (4.99e-2)" "unprognostic (1.16e-3)" "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (9.74e-2)" "unprognostic (1.63e-1)" "unprognostic (1.66e-1)" "unprognostic (9.35e-4)" "unprognostic (1.54e-3)" "unprognostic (6.95e-2)" "unprognostic (1.86e-1)" "unprognostic (7.31e-2)" 1.5 0.3 0.8 7.9 1.0 7.0 0.5 0.9 1.3 0.4 1.3 0.5 0.3 0.3 0.1 0.5 0.6 17.6 0.5 0.8 1.0 1.2 840.7 2.5 0.9 1.0 1.1 0.2 0.5 0.1 0.2 0.5 1.2 0.4 0.4 0.0 0.5 0.2 0.2 5.2 0.6 1.3 1.0 6.8 0.5 0.5 1.4 0.5 0.3 0.1 1.0 2.0 0.4 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 62.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 528.3 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 42.3 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 1.0 110.0 0.8 0.1 11.2 0.2 0.0 0.0 0.0 64.1 0.0 0.1 0.0 1.7 0.1 0.1 1.6 0.3 31.8 0.8 1.0 0.9 1.3 0.8 1.0 1.0 1.1 1.2 1.0 1.4 1.2 0.0 0.0 5.1 0.3 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 150.2 0.0 0.0 0.0 0.1 0.0 0.1 1.9 0.0 0.4 0.0 0.0 1.3 7.1 19.6 1.9 0.0 0.2 0.1 0.0 0.1 2.5 0.0 16.1 878.6 8.4 0.0 0.1 0.1 0.0 41.1 7.7 0.7 0.0 19.6 0.0 0.0 15.3 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 6.6 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.3 0.4 1.4 0.0 0.0 0.1 ASMTL ENSG00000169093 "Acetylserotonin O-methyltransferase like" O95671 X 1403139-1453762 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" "Hydrolase, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 92.5;monocytes: 106.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 131.0" "Low region specificity" "Detected in all" "HPA003630, HPA021865" Supported Enhanced Cytosol NA NA 17000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA003630: AB_1078230, HPA021865: AB_1845099" "unprognostic (3.89e-2)" "unprognostic (1.14e-3)" "unprognostic (2.28e-1)" "unprognostic (1.87e-2)" "unprognostic (7.99e-2)" "unprognostic (9.05e-2)" "unprognostic (8.17e-2)" "unprognostic (5.23e-2)" "unprognostic (8.40e-2)" "unprognostic (1.24e-1)" "unprognostic (1.91e-3)" "unprognostic (7.24e-2)" "unprognostic (3.26e-3)" "unprognostic (9.70e-2)" "unprognostic (8.38e-2)" "unprognostic (2.91e-1)" "unprognostic (2.20e-1)" 28.1 21.8 15.6 15.7 15.1 17.4 26.8 15.1 20.3 29.1 23.0 30.8 11.7 29.4 14.3 15.1 28.6 13.6 34.5 15.7 16.5 23.1 32.1 18.3 21.4 20.4 18.4 33.9 23.6 22.4 31.0 11.2 18.3 26.8 7.8 9.4 24.8 23.4 23.8 27.7 20.6 12.2 15.9 24.1 23.1 13.0 16.6 20.0 29.5 15.3 12.4 25.1 22.9 18.0 14.0 24.0 28.0 21.4 16.5 25.5 38.9 16.3 21.3 18.2 23.2 22.0 16.5 24.6 9.0 21.5 19.7 5.1 7.4 7.9 11.4 36.7 23.9 21.4 17.0 26.6 37.5 10.1 131.0 33.9 13.4 13.9 13.4 20.3 21.7 18.7 11.0 19.3 14.6 52.4 43.5 39.6 33.9 12.9 15.0 35.2 26.7 60.0 12.8 7.6 1.1 13.2 21.9 27.8 20.7 18.9 6.4 13.4 28.6 15.2 16.5 29.0 6.1 24.8 8.0 62.9 19.3 14.5 4.6 45.7 25.5 65.9 28.8 30.9 25.6 24.2 26.1 26.9 22.0 37.7 22.5 17.7 37.2 52.9 22.5 42.1 31.4 23.2 15.6 15.1 15.1 20.3 15.7 16.5 20.4 18.4 18.3 15.9 16.6 18.0 20.6 12.8 9.4 5.2 19.3 18.4 25.3 17.2 23.3 17.7 16.4 17.4 21.3 10.0 9.9 14.7 4.2 33.4 28.8 16.1 27.4 15.2 0.9 8.8 14.3 19.5 14.4 7.4 8.3 17.1 24.1 23.8 14.8 10.4 54.6 27.0 17.9 30.8 20.3 92.5 6.7 17.9 8.2 12.3 31.0 2.8 26.1 18.8 12.4 9.4 106.2 17.1 26.8 5.0 7.1 10.9 18.3 43.2 21.8 22.1 19.9 34.2 11.1 12.6 32.9 21.4 23.2 2.5 8.2 22.3 15.6 66.4 20.4 21.9 20.4 18.4 ASPA "ACY2, ASP" ENSG00000108381 Aspartoacylase P45381 17 3472374-3503405 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.0;kidney: 38.2" "Cell type enhanced" "Detected in many" "Leydig cells: 49.7;Melanocytes: 46.2;Oligodendrocytes: 217.0;Peritubular cells: 48.2;Proximal enterocytes: 37.5;Proximal tubular cells: 74.8" "Cancer enhanced" "Detected in some" "renal cancer: 7.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "ASC diff: 5.4;ASC TERT1: 4.1;CACO-2: 3.8;HSkMC: 7.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022142, HPA022145" Enhanced Supported Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA022142: AB_1845102, HPA022145: AB_1845103" "unprognostic (4.42e-2)" "unprognostic (4.79e-2)" "unprognostic (2.02e-2)" "unprognostic (2.79e-3)" "unprognostic (4.36e-2)" "unprognostic (5.01e-1)" "unprognostic (1.08e-3)" "unprognostic (3.57e-1)" "unprognostic (4.17e-1)" "unprognostic (3.43e-1)" "unprognostic (5.27e-2)" "unprognostic (6.27e-2)" "unprognostic (1.25e-1)" "unprognostic (7.07e-4)" "unprognostic (2.77e-1)" "unprognostic (4.68e-1)" "unprognostic (1.49e-1)" 13.9 4.3 25.9 1.8 46.4 1.8 4.1 27.6 40.9 7.5 14.2 4.3 11.2 4.5 6.0 4.9 5.5 3.6 2.7 25.8 27.7 38.2 15.0 3.5 1.5 30.4 35.4 2.9 1.0 0.8 0.8 3.5 29.5 4.1 4.9 2.8 1.8 5.0 11.9 5.2 15.6 3.1 24.7 5.4 4.4 6.6 42.4 0.6 2.1 15.0 0.7 6.3 4.3 69.0 0.2 0.1 0.5 0.5 5.4 4.1 0.3 0.2 0.1 0.2 0.1 3.8 0.2 0.6 0.2 0.7 0.3 0.3 0.3 0.1 0.2 2.0 0.1 0.4 0.7 0.2 0.5 0.4 0.4 7.5 0.3 0.4 0.1 0.1 0.1 0.4 0.3 1.1 0.2 0.2 0.2 0.6 0.4 0.2 0.3 0.3 0.3 0.6 0.2 1.1 0.4 0.3 1.1 0.3 0.9 0.4 0.3 0.2 0.4 0.6 0.4 0.4 0.3 0.7 0.4 0.4 0.2 0.4 0.5 1.1 0.1 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.3 0.2 0.2 0.7 0.3 0.1 0.2 0.1 0.0 25.9 46.4 27.6 40.9 25.8 27.7 30.4 35.4 29.5 24.7 42.4 69.0 5.1 9.6 1.5 12.1 0.1 5.2 1.5 1.6 6.2 5.5 2.1 0.8 1.3 2.8 1.0 25.8 0.0 0.0 0.0 0.3 7.9 0.2 5.0 0.1 4.1 1.1 2.4 2.7 0.6 0.2 0.1 15.0 2.0 0.2 0.0 0.1 3.9 11.5 0.2 8.4 0.4 0.8 2.0 0.8 1.5 2.5 49.7 0.8 46.2 3.7 0.0 4.1 0.0 1.5 217.0 0.0 2.5 48.2 0.2 0.4 37.5 74.8 0.1 0.5 0.0 8.5 11.6 11.1 0.6 0.7 1.7 0.1 0.4 28.3 1.8 2.7 ATP1B2 AMOG ENSG00000129244 "ATPase Na+/K+ transporting subunit beta 2" P14415 17 7646627-7657770 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 11 "brain: 395.1;retina: 614.8" "Group enriched" "Detected in many" 5 "Astrocytes: 207.3;Bipolar cells: 330.2;Cone photoreceptor cells: 250.2;Muller glia cells: 303.2;Rod photoreceptor cells: 226.1" "Cancer enriched" "Detected in many" 17 "glioma: 200.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.6;HAP1: 2.9;K-562: 4.5;SuSa: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010698 Supported NA NA 160000 "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "HPA010698: AB_1845174" "unprognostic (9.39e-2)" "unprognostic (1.86e-2)" "unprognostic (3.89e-3)" "unprognostic (4.96e-3)" "unprognostic (3.90e-3)" "unprognostic (9.33e-2)" "unprognostic (4.86e-1)" "unprognostic (5.93e-2)" "unprognostic (5.43e-2)" "unprognostic (1.29e-2)" "prognostic favorable (1.05e-4)" "unprognostic (1.10e-1)" "prognostic unfavorable (4.17e-4)" "unprognostic (4.60e-3)" "unprognostic (1.43e-1)" "unprognostic (2.24e-1)" "unprognostic (3.79e-2)" 6.1 10.1 212.3 0.9 251.6 11.4 5.0 268.1 288.8 13.3 25.8 9.1 1.2 8.8 17.4 2.2 12.3 3.6 8.6 196.9 250.0 10.1 2.7 4.2 1.7 353.9 395.1 29.5 2.5 4.5 45.3 4.5 282.6 6.6 2.7 614.8 1.9 7.5 4.3 2.3 3.5 5.5 256.3 5.0 3.8 5.5 364.8 0.8 4.6 5.3 1.1 4.6 7.7 174.7 0.0 0.0 9.6 0.4 0.3 0.2 0.1 0.1 0.0 0.3 0.2 0.4 0.0 0.3 0.2 0.1 0.2 0.3 2.9 0.2 0.1 0.1 1.2 0.2 0.1 0.1 0.1 0.0 0.9 0.5 0.0 0.3 0.0 0.1 0.0 0.2 4.5 0.5 0.0 0.2 0.2 0.3 2.0 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.1 1.8 0.0 0.1 0.0 5.7 0.1 0.2 0.0 0.1 0.7 0.0 0.2 0.4 0.1 0.0 0.9 0.2 0.2 0.2 0.1 0.0 0.3 0.0 0.2 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.1 212.3 251.6 268.1 288.8 196.9 250.0 353.9 395.1 282.6 256.3 364.8 174.7 8.5 0.0 0.0 207.3 1.8 1.9 0.4 0.0 1.8 330.2 2.3 6.2 3.7 2.8 0.0 0.0 250.2 0.0 1.1 6.7 0.0 0.2 0.2 0.8 8.3 7.7 0.0 49.2 2.9 0.0 0.1 5.9 7.7 0.6 0.0 1.0 11.4 0.2 0.3 18.5 38.8 2.4 2.0 0.8 0.9 2.3 18.6 1.6 0.0 7.5 0.2 303.2 0.0 45.8 1.6 0.0 0.0 46.3 0.8 0.5 0.5 0.2 0.0 226.1 26.3 2.4 50.0 1.2 6.1 1.6 1.1 0.3 1.6 0.5 2.6 0.2 ATP5IF1 "ATPI, ATPIF1, ATPIP, IP, MGC1167, MGC8898" ENSG00000130770 "ATP synthase inhibitory factor subunit 1" Q9UII2 1 28236109-28246906 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 1035.0;Endometrial ciliated cells: 1524.2;Exocrine glandular cells: 672.1;Granulosa cells: 1030.6;Proximal tubular cells: 1502.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027999 Supported Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA027999: AB_10600984" "unprognostic (2.80e-2)" "unprognostic (3.72e-2)" "unprognostic (2.95e-1)" "prognostic favorable (6.38e-8)" "unprognostic (2.04e-1)" "unprognostic (1.76e-1)" "unprognostic (6.57e-2)" "unprognostic (2.93e-2)" "unprognostic (1.40e-2)" "prognostic favorable (8.20e-4)" "unprognostic (5.94e-2)" "unprognostic (3.52e-1)" "unprognostic (6.15e-3)" "unprognostic (4.68e-2)" "unprognostic (2.02e-1)" "unprognostic (2.79e-1)" "unprognostic (1.48e-3)" 96.9 215.1 98.4 50.6 98.6 144.3 108.8 95.6 140.0 123.3 95.2 234.8 163.1 113.0 44.5 184.5 139.4 28.0 585.8 100.0 106.5 384.9 342.6 116.0 64.5 99.6 96.8 134.9 163.4 90.1 246.5 37.6 97.8 156.0 59.4 71.0 145.3 37.1 456.7 165.0 199.6 28.5 93.7 153.7 215.7 355.5 99.6 60.0 169.2 179.8 47.9 116.6 134.0 104.1 271.9 136.4 79.3 75.1 58.0 62.7 94.1 118.6 57.9 98.6 96.2 132.0 192.5 189.1 173.8 72.1 37.6 161.5 91.2 118.0 77.6 143.9 306.0 162.9 612.7 180.8 62.9 125.5 158.1 73.5 190.2 88.2 70.4 96.2 95.7 222.0 292.9 167.9 71.2 178.0 187.6 230.4 262.7 100.9 167.8 177.3 87.5 270.2 196.9 175.5 158.9 114.2 146.5 150.8 160.4 76.5 224.4 136.6 100.6 31.9 88.0 126.5 142.1 432.0 282.8 268.6 151.1 338.8 38.1 133.3 116.6 126.1 144.2 111.1 145.8 195.2 154.3 155.5 142.8 154.0 144.1 139.3 102.7 142.9 102.7 213.5 226.9 214.1 98.4 98.6 95.6 140.0 100.0 106.5 99.6 96.8 97.8 93.7 99.6 104.1 207.3 205.1 284.9 0.0 61.7 0.0 0.0 0.0 0.0 0.0 251.1 314.3 0.0 0.0 150.4 546.2 0.0 453.8 165.4 0.0 1035.0 396.6 0.0 1524.2 210.6 84.0 0.0 0.0 0.0 672.1 226.0 114.6 0.0 453.2 172.8 1030.6 0.0 0.0 372.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.6 0.0 0.0 123.0 0.0 0.0 0.0 0.0 550.3 0.0 0.0 30.3 0.0 0.0 1502.7 621.6 0.0 0.0 0.0 90.6 0.0 0.0 0.0 0.0 251.7 92.0 281.6 0.0 0.0 ATXN7L1 "ATXN7L4, KIAA1218, MGC33190" ENSG00000146776 "Ataxin 7 like 1" Q9ULK2 7 105604772-105876599 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 60.7;Early spermatids: 93.4;Excitatory neurons: 107.3;Inhibitory neurons: 96.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021448 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "HPA021448: AB_1845213" "unprognostic (1.60e-1)" "unprognostic (1.53e-1)" "unprognostic (4.36e-2)" "unprognostic (1.01e-2)" "unprognostic (2.84e-1)" "unprognostic (8.20e-3)" "unprognostic (3.69e-1)" "unprognostic (2.51e-2)" "unprognostic (8.71e-2)" "unprognostic (1.02e-1)" "unprognostic (1.41e-1)" "unprognostic (8.65e-2)" "unprognostic (2.22e-1)" "unprognostic (3.79e-1)" "unprognostic (5.75e-2)" "unprognostic (1.07e-1)" "unprognostic (2.01e-1)" 5.0 4.3 2.8 4.4 3.0 4.3 4.5 5.0 4.3 6.6 0.6 5.3 4.1 4.7 4.5 4.1 5.8 4.3 2.6 2.8 1.3 7.3 6.3 4.0 6.4 1.6 1.7 6.5 3.2 4.9 3.3 5.7 1.5 4.7 5.9 2.0 5.8 3.8 2.3 5.9 5.0 4.1 0.1 5.7 4.8 10.2 1.8 10.1 5.0 3.1 5.9 4.5 5.2 2.7 3.2 4.3 9.0 4.2 5.5 6.5 2.8 5.7 5.6 5.0 4.6 4.2 6.1 1.3 4.3 6.1 4.4 3.0 5.1 5.9 3.7 18.0 3.3 4.3 3.2 4.1 3.3 7.1 13.9 4.5 4.7 3.3 3.3 3.7 4.6 3.0 5.2 2.8 4.2 7.7 3.9 4.3 16.7 9.0 4.3 3.8 3.0 1.0 3.8 3.2 5.6 3.7 4.0 8.0 7.9 8.9 4.1 7.2 11.5 7.8 3.5 6.5 2.2 0.6 0.0 0.1 4.8 10.9 8.0 2.3 3.8 4.2 2.4 4.4 1.8 3.5 6.5 5.6 2.9 3.5 6.9 3.9 1.3 4.4 2.8 1.9 14.3 3.3 2.8 3.0 5.0 4.3 2.8 1.3 1.6 1.7 1.5 0.1 1.8 2.7 8.3 0.0 3.9 60.7 8.0 5.1 5.4 4.9 6.2 7.8 5.2 3.9 2.4 4.3 3.6 5.5 2.1 6.3 16.8 11.3 5.9 3.9 93.4 13.1 6.4 5.2 5.4 9.4 107.3 2.6 3.6 5.9 11.2 7.9 5.1 7.9 6.4 17.0 7.5 8.4 96.3 8.5 2.0 11.6 6.1 56.6 6.5 9.3 8.8 55.3 10.8 2.0 19.6 46.8 51.3 4.2 11.0 4.5 7.4 4.6 43.7 42.6 14.9 1.0 6.6 7.5 6.4 20.9 2.5 7.0 4.0 5.3 13.3 7.7 9.4 3.7 AUH ENSG00000148090 "AU RNA binding methylglutaconyl-CoA hydratase" Q13825 9 91213815-91361918 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Branched-chain amino acid catabolism" "Lyase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 191.7;Inhibitory neurons: 137.0;Oligodendrocytes: 137.5;Proximal tubular cells: 120.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 82.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004171 Enhanced "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "HPA004171: AB_1845215" "unprognostic (4.10e-2)" "unprognostic (8.95e-2)" "unprognostic (5.56e-2)" "unprognostic (1.19e-1)" "unprognostic (1.54e-1)" "unprognostic (1.49e-1)" "unprognostic (3.24e-2)" "unprognostic (3.05e-2)" "unprognostic (3.57e-1)" "unprognostic (1.11e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-1)" "prognostic favorable (0.00e+0)" "unprognostic (8.23e-3)" "unprognostic (2.84e-2)" "unprognostic (1.23e-1)" "unprognostic (1.23e-1)" 17.2 41.9 11.8 6.3 12.3 4.8 15.9 16.0 15.3 13.6 17.9 17.2 23.8 10.2 14.2 8.6 12.4 10.7 38.9 12.1 14.3 62.9 26.4 10.3 7.6 14.8 13.6 13.4 25.5 45.4 10.4 16.1 15.2 28.2 17.2 21.4 26.1 14.8 24.2 8.7 20.1 8.6 12.2 8.0 22.7 5.5 14.1 9.0 21.0 29.2 7.7 9.1 9.8 15.0 9.1 8.7 12.0 6.2 14.5 15.5 18.5 8.0 10.0 6.1 7.0 5.0 11.4 10.6 8.1 8.5 18.2 13.0 18.1 10.1 8.7 82.6 15.4 7.3 9.7 29.6 11.1 10.6 7.3 13.1 12.5 4.9 16.8 14.3 7.6 10.7 10.3 15.5 7.2 8.8 14.6 23.8 15.0 22.2 12.5 8.5 9.6 18.6 26.6 4.8 12.2 8.8 11.9 28.3 15.6 27.1 5.2 6.9 7.8 6.1 7.6 9.0 7.8 17.7 16.1 3.6 9.6 8.5 4.2 17.9 5.2 18.2 7.2 3.6 8.1 8.4 7.8 10.4 4.6 11.8 9.6 9.1 7.4 10.8 2.5 6.3 10.8 6.5 11.8 12.3 16.0 15.3 12.1 14.3 14.8 13.6 15.2 12.2 14.1 15.0 9.6 0.0 7.7 75.1 11.2 5.2 24.5 27.7 12.5 18.7 15.8 13.5 37.2 27.1 19.1 27.6 25.0 44.6 11.5 27.0 191.7 29.6 3.1 11.5 11.1 11.1 22.9 28.8 101.2 16.1 28.9 14.2 19.4 16.0 1.3 14.5 11.0 18.3 13.4 13.5 137.0 17.3 38.7 8.9 4.7 1.1 14.3 8.9 12.4 67.5 29.1 9.5 18.6 100.5 137.5 12.5 23.5 11.3 18.4 36.8 59.4 120.0 15.8 34.4 13.1 11.9 11.5 8.7 10.5 16.1 4.1 36.4 12.9 11.6 25.0 24.2 AZGP1 "ZA2G, ZAG" ENSG00000160862 "Alpha-2-glycoprotein 1, zinc-binding" P25311 7 99966720-99976042 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 2809.6;salivary gland: 3847.3" "Cell type enhanced" "Detected in many" "Breast glandular cells: 1315.5;Breast myoepithelial cells: 704.8;Hepatocytes: 4270.8;Ionocytes: 901.3;Prostatic glandular cells: 1691.9;Urothelial cells: 674.2" "Group enriched" "Detected in many" 12 "breast cancer: 412.6;liver cancer: 273.6;prostate cancer: 469.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 56.6;OE19: 158.9;RPMI-8226: 130.4;T-47d: 41.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012582, HPA012876, CAB016087, CAB032276" Enhanced Approved Nucleoplasm,Vesicles "Secreted to blood" NA NA 55200000000 74000000000 "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" Vesicles Nucleoplasm "CAB016087: AB_667849, CAB032276: AB_2062580, HPA012582: AB_1845226, HPA012876: " "unprognostic (8.14e-2)" "unprognostic (1.50e-1)" "unprognostic (3.41e-1)" "unprognostic (5.42e-3)" "unprognostic (4.98e-2)" "unprognostic (5.74e-3)" "prognostic favorable (2.90e-4)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (2.19e-1)" "unprognostic (2.35e-2)" "unprognostic (1.79e-1)" "prognostic favorable (1.53e-4)" "unprognostic (2.18e-1)" "unprognostic (2.08e-2)" "unprognostic (9.80e-2)" "unprognostic (3.51e-3)" 128.6 3.9 17.1 2.7 28.8 0.4 1061.4 23.1 18.8 3.4 16.0 6.7 30.9 1.5 2.5 22.0 3.0 38.7 114.7 14.9 22.2 326.8 2809.6 14.8 0.4 20.2 23.3 6.0 752.1 0.1 1.3 0.5 27.1 1051.4 4.2 3.6 3847.3 40.2 1.7 206.8 28.6 0.3 14.0 1.4 315.2 25.9 21.4 0.8 1.9 2.3 1.5 5.8 7.5 24.5 0.2 0.0 0.0 0.0 11.3 0.0 5.5 0.0 0.0 0.0 0.0 0.1 4.0 14.2 0.7 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.1 0.3 0.1 56.6 4.9 1.5 0.1 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.3 29.9 0.0 0.0 0.0 5.1 0.2 158.9 0.0 0.0 1.7 130.4 0.0 0.0 0.0 2.0 1.0 25.4 13.0 0.0 41.8 0.0 0.0 0.5 0.1 1.8 0.9 1.9 0.8 0.4 0.0 0.5 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 28.8 23.1 18.8 14.9 22.2 20.2 23.3 27.1 14.0 21.4 24.5 9.9 22.4 276.8 0.0 14.7 4.2 422.1 25.3 0.0 0.0 1315.5 704.8 115.9 451.8 63.0 5.5 2.1 0.0 10.4 5.5 46.9 11.7 1.9 1.4 1.2 14.2 12.4 85.5 0.1 254.2 0.0 7.7 94.8 5.5 3.8 1.2 65.3 4270.8 0.0 0.0 0.1 13.1 901.3 93.1 0.7 4.2 0.9 14.8 62.2 1.0 2.0 23.7 0.0 7.5 7.3 221.5 6.4 0.0 0.3 1691.9 15.3 596.1 6.3 0.3 0.0 0.0 11.9 7.4 0.4 9.9 9.7 0.0 12.3 0.1 12.6 674.2 AZU1 "AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC" ENSG00000172232 "Azurocidin 1" P20160 19 825097-832018 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Heparin-binding, Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 48 "bone marrow: 1578.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 4.5;Breast myoepithelial cells: 4.6;Endometrial ciliated cells: 8.9;Erythroid cells: 8.8;Respiratory ciliated cells: 4.5;Skeletal myocytes: 5.7;Spermatogonia: 6.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 9 "neutrophil: 3.3" "Lineage enriched" "Detected in single" 9 "granulocytes: 3.3" "Cell line enriched" "Detected in some" 15 "THP-1: 659.5" "Not detected" "Not detected" "HPA055851, HPA075964" Enhanced Enhanced Vesicles "Secreted to blood" NA NA 320000 "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA055851: AB_2682943, HPA075964: " "unprognostic (1.12e-2)" "unprognostic (3.71e-2)" "unprognostic (4.44e-2)" "unprognostic (8.85e-3)" "unprognostic (1.62e-2)" "unprognostic (1.29e-1)" "unprognostic (1.39e-1)" "unprognostic (8.12e-2)" "unprognostic (3.32e-1)" "unprognostic (4.22e-3)" "unprognostic (2.58e-1)" "unprognostic (1.50e-1)" "unprognostic (1.01e-6)" "unprognostic (1.11e-2)" "unprognostic (1.10e-1)" "unprognostic (2.46e-2)" "unprognostic (3.04e-2)" 0.8 0.2 0.4 0.0 0.4 1578.1 1.5 0.2 0.9 0.2 0.2 0.2 0.0 0.5 0.0 0.1 1.4 0.0 2.0 0.4 0.3 0.4 2.8 15.9 0.6 0.3 0.3 0.2 0.2 0.0 0.9 0.9 0.4 0.4 0.0 0.0 2.6 0.0 0.5 0.6 0.2 0.0 0.2 33.1 0.2 2.4 0.4 3.1 0.5 0.0 0.0 0.3 0.2 0.3 1.1 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 44.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.4 0.6 659.5 0.0 0.0 0.1 0.0 0.8 0.0 0.1 0.6 0.0 34.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.3 0.0 0.1 0.0 0.0 0.1 0.4 0.4 0.2 0.9 0.4 0.3 0.3 0.3 0.4 0.2 0.4 0.3 3.5 0.0 0.0 0.0 0.6 0.0 0.1 1.2 0.0 0.0 4.5 4.6 0.7 0.0 0.5 0.0 0.0 0.2 2.8 0.6 0.0 0.1 0.0 8.9 1.2 1.0 0.0 8.8 0.8 0.0 0.3 0.8 0.0 2.3 0.0 0.1 0.0 0.4 3.2 0.0 1.4 0.4 0.0 3.7 0.4 0.7 0.0 3.2 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.2 0.2 0.0 4.5 0.0 0.0 5.7 1.2 0.1 6.4 0.9 0.1 0.0 1.0 0.0 0.6 0.0 BCKDHA "MSU, OVD1A" ENSG00000248098 "Branched chain keto acid dehydrogenase E1 subunit alpha" P12694 19 41397808-41425002 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Maple syrup urine disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 26.2;Gastric mucus-secreting cells: 23.4;Plasma cells: 25.0;Squamous epithelial cells: 27.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036640 Supported NA NA 7700 "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "HPA036640: AB_10671964" "unprognostic (4.50e-2)" "unprognostic (6.85e-2)" "unprognostic (1.14e-1)" "unprognostic (8.58e-3)" "unprognostic (1.26e-2)" "prognostic favorable (9.37e-4)" "unprognostic (2.41e-2)" "unprognostic (8.55e-2)" "unprognostic (1.82e-1)" "unprognostic (1.48e-2)" "unprognostic (1.12e-2)" "unprognostic (1.53e-1)" "prognostic favorable (5.33e-10)" "unprognostic (1.73e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (3.27e-5)" "unprognostic (9.66e-2)" 33.8 78.4 32.0 19.3 35.5 32.4 25.2 37.0 39.3 24.6 37.0 20.9 19.9 17.9 14.1 65.1 28.8 15.4 90.4 32.5 35.1 44.3 110.0 22.4 24.5 34.4 33.8 25.4 46.1 56.3 24.0 19.0 36.2 23.8 15.0 21.7 40.9 23.1 110.0 31.8 18.7 12.7 33.9 24.4 52.5 27.1 35.7 27.0 41.7 122.0 21.2 21.7 31.9 40.0 42.7 75.1 14.2 44.1 22.2 12.8 17.1 11.9 25.3 24.4 29.9 18.2 36.0 34.6 23.7 15.1 11.0 17.1 15.0 25.9 12.1 36.0 41.0 27.1 35.2 21.3 51.5 25.5 17.7 27.6 37.6 16.9 38.2 36.0 45.0 50.9 25.9 68.9 17.6 41.5 28.0 20.0 12.8 61.1 21.1 27.1 22.8 89.6 29.8 19.8 32.5 38.6 39.6 84.7 34.1 12.1 45.4 81.0 29.3 22.2 23.0 12.0 22.0 131.9 55.1 34.1 81.8 56.6 24.6 61.4 149.4 59.7 49.5 123.9 56.7 46.0 47.0 49.1 154.6 49.5 43.2 44.9 46.4 82.4 95.5 62.6 63.9 125.6 32.0 35.5 37.0 39.3 32.5 35.1 34.4 33.8 36.2 33.9 35.7 40.0 0.6 0.0 13.1 4.9 10.0 0.3 0.1 2.6 26.2 0.2 1.5 0.4 0.1 1.5 5.3 5.5 0.0 1.9 0.9 3.8 3.9 14.7 0.7 0.5 0.6 2.4 6.1 15.5 5.8 11.8 1.7 3.7 23.4 0.7 5.1 0.4 2.5 2.4 2.7 0.0 6.2 7.6 8.2 2.2 0.8 0.9 0.6 6.6 3.6 3.7 12.4 0.4 5.2 4.0 5.7 8.4 3.8 0.4 25.0 0.2 6.7 2.3 1.2 1.2 0.0 0.2 3.6 1.8 0.9 27.2 0.9 2.1 6.3 0.3 7.3 0.1 BCL6B "BAZF, ZBTB28, ZNF62" ENSG00000161940 "BCL6B transcription repressor" Q8N143 17 7023050-7030290 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 37.8;Endothelial cells: 45.0;Hepatic stellate cells: 23.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 18.2;HMC-1: 53.2;HUVEC TERT2: 96.2;TIME: 38.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA059147, HPA075112" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Vesicles, Plasma membrane" "HPA059147: AB_2683928, HPA075112: AB_2732279" "unprognostic (5.61e-2)" "unprognostic (9.43e-3)" "unprognostic (2.33e-2)" "unprognostic (2.12e-1)" "unprognostic (1.40e-1)" "prognostic favorable (8.56e-5)" "unprognostic (2.81e-1)" "unprognostic (2.28e-2)" "unprognostic (4.81e-2)" "unprognostic (1.80e-1)" "unprognostic (6.10e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (4.04e-4)" "unprognostic (7.14e-2)" "unprognostic (1.11e-1)" "unprognostic (4.29e-2)" "unprognostic (4.26e-2)" 29.8 5.6 8.1 5.7 7.0 0.1 15.4 6.2 9.2 5.7 4.4 4.4 3.2 7.7 0.7 3.8 5.1 13.4 23.3 6.5 6.9 13.4 4.0 28.9 5.5 7.8 7.1 2.9 3.8 3.1 5.5 19.9 7.3 4.5 2.2 0.6 4.0 3.5 11.5 4.4 4.9 7.7 6.6 13.0 4.3 2.0 10.1 2.0 12.0 14.7 2.1 7.9 4.8 6.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 18.2 0.0 0.0 0.5 0.0 53.2 0.0 0.0 0.0 0.1 0.0 96.2 0.2 3.4 0.4 0.0 0.0 0.2 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.2 38.2 0.8 0.2 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.2 9.2 6.5 6.9 7.8 7.1 7.3 6.6 10.1 6.7 37.8 3.2 4.2 0.0 0.5 2.2 0.0 0.0 0.0 0.0 0.2 0.3 2.9 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.3 45.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.1 23.6 0.2 0.1 0.0 0.0 0.2 0.0 1.9 2.3 0.0 0.0 0.3 3.6 4.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.4 0.0 0.1 0.0 0.2 0.0 0.9 0.8 0.6 1.5 0.4 1.3 0.1 0.2 0.9 0.0 0.5 BHLHE22 "Beta3, BHLHB5, CAGL85, TNRC20" ENSG00000180828 "Basic helix-loop-helix family member e22" Q8NFJ8 8 64580365-64583627 "Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 23.2" "Cell type enriched" "Detected in some" 14 "Bipolar cells: 64.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 23 "THP-1: 78.4" "Group enriched" "Detected in all" 5 "amygdala: 30.7;cerebellum: 30.7;cerebral cortex: 22.7;hippocampal formation: 46.3;white matter: 13.1" "HPA064128, HPA064872, HPA067500" Enhanced Approved "Nucleoplasm,Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Nuclear speckles" "Centrosome, Cytosol" "HPA064128: AB_2685195, HPA064872: AB_2685377, HPA067500: AB_2685855" "unprognostic (9.17e-2)" "unprognostic (1.11e-2)" "unprognostic (5.44e-2)" "unprognostic (2.28e-5)" "unprognostic (7.22e-3)" "unprognostic (6.47e-4)" "unprognostic (2.41e-1)" "unprognostic (1.08e-1)" "unprognostic (1.30e-1)" "unprognostic (6.58e-2)" "unprognostic (1.52e-1)" "unprognostic (3.71e-2)" "unprognostic (2.86e-7)" "unprognostic (3.20e-2)" "unprognostic (2.29e-1)" "unprognostic (6.72e-3)" "unprognostic (1.86e-1)" 2.0 0.5 8.9 1.4 6.6 0.0 1.5 12.1 22.4 2.3 0.4 1.3 0.4 0.3 0.1 0.9 0.8 0.4 0.3 23.2 1.5 0.2 0.5 2.0 0.7 5.5 1.5 0.2 0.7 0.1 1.4 0.0 2.6 0.4 0.5 4.4 0.5 2.3 0.1 0.8 1.4 0.4 1.4 1.4 0.5 0.2 1.1 0.3 0.7 0.0 0.6 1.2 2.9 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 78.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 6.6 12.1 22.4 23.2 1.5 5.5 1.5 2.6 1.4 1.1 1.8 0.3 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 64.7 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 1.2 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.1 0.0 3.4 0.2 0.0 0.0 0.6 1.5 0.0 1.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 3.0 0.0 0.2 2.9 0.0 0.4 0.1 1.6 0.0 0.1 0.0 0.0 0.0 BICDL2 CCDC64B ENSG00000162069 "BICD family like cargo adaptor 2" A1A5D9 16 3027682-3036944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 104.8;pancreas: 127.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 52.2;Breast myoepithelial cells: 22.1;Ductal cells: 34.3;Endometrial ciliated cells: 28.9;Exocrine glandular cells: 49.8;Glandular and luminal cells: 28.3;Pancreatic endocrine cells: 35.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 9.0;BEWO: 15.4;CAPAN-2: 14.4;HaCaT: 22.5;MCF7: 22.8;RT4: 10.8;SK-BR-3: 11.0;T-47d: 14.0" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 2.7" HPA043251 Approved Approved "Intermediate filaments,Actin filaments,Cytosol" No NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 30: Mammary glandular cells - Lactation" "Intermediate filaments, Actin filaments, Cytosol" "HPA043251: AB_10794925" "unprognostic (2.00e-1)" "unprognostic (5.37e-2)" "unprognostic (1.71e-1)" "unprognostic (6.06e-3)" "unprognostic (9.65e-5)" "unprognostic (5.79e-3)" "unprognostic (6.47e-2)" "unprognostic (1.75e-2)" "unprognostic (2.45e-1)" "unprognostic (1.66e-2)" "unprognostic (2.05e-2)" "unprognostic (4.71e-2)" "unprognostic (8.56e-2)" "unprognostic (2.55e-2)" "unprognostic (2.38e-1)" "unprognostic (4.32e-2)" "prognostic favorable (9.04e-4)" 0.4 0.0 0.2 1.9 0.2 0.0 8.6 0.4 0.4 20.7 0.1 25.1 10.4 0.7 2.6 104.8 6.0 3.4 0.0 0.2 0.1 5.8 0.9 5.9 0.0 0.6 0.3 0.1 127.2 4.1 1.5 0.3 0.8 16.8 6.4 0.0 44.4 3.2 0.6 43.8 13.5 0.2 0.2 0.2 21.5 0.1 0.3 0.2 6.1 0.0 3.1 11.4 44.3 0.2 9.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 2.6 14.4 0.0 0.0 0.0 0.0 22.5 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.1 0.0 6.4 0.0 0.1 0.0 0.2 0.0 10.8 0.2 0.1 0.0 11.0 0.0 0.3 14.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.4 0.4 0.2 0.1 0.6 0.3 0.8 0.2 0.3 0.2 0.3 12.8 18.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 52.2 22.1 0.0 0.0 12.4 16.5 0.0 4.5 1.3 0.0 3.9 34.3 0.0 28.9 2.8 0.5 0.0 0.0 0.0 49.8 6.1 0.6 0.0 28.3 2.5 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 35.8 0.0 0.0 0.1 0.0 0.0 0.2 12.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.5 0.6 0.3 0.0 0.0 BMERB1 "C16orf45, FLJ32618" ENSG00000166780 "BMERB domain containing 1" Q96MC5 16 15434475-15625028 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 57.0" "Cancer enhanced" "Detected in all" "glioma: 30.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 8.7" "Lineage enriched" "Detected in many" 4 "T-cells: 8.7" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 101.8;U-2197: 81.3;U-87 MG: 124.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041114, HPA063757" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" Cytosol Nucleoplasm "HPA041114: AB_10794542, HPA063757: " "unprognostic (1.02e-1)" "unprognostic (2.22e-1)" "unprognostic (1.67e-2)" "unprognostic (6.96e-2)" "unprognostic (3.79e-2)" "unprognostic (1.21e-1)" "prognostic favorable (1.53e-4)" "unprognostic (3.23e-2)" "unprognostic (1.90e-2)" "unprognostic (1.16e-2)" "unprognostic (3.64e-2)" "unprognostic (5.28e-2)" "prognostic favorable (1.75e-4)" "unprognostic (3.79e-3)" "unprognostic (8.31e-2)" "unprognostic (1.71e-1)" "unprognostic (1.58e-1)" 30.9 15.4 90.3 10.5 111.6 1.1 21.6 67.4 112.7 46.0 48.2 46.1 8.3 40.5 19.7 21.4 38.4 23.9 47.3 107.0 87.2 23.1 21.8 13.4 6.4 123.0 74.0 40.9 18.6 3.9 40.8 1.3 118.5 32.4 9.3 40.6 12.6 27.6 86.9 13.0 19.1 35.6 69.6 9.2 21.6 40.3 80.5 4.0 13.5 41.3 4.0 44.4 25.3 96.2 1.4 31.5 12.8 1.5 56.7 50.7 0.3 18.1 62.6 15.5 8.4 0.0 0.9 0.1 4.0 101.8 37.5 0.2 4.1 5.3 7.9 0.4 0.7 6.7 11.9 1.5 19.4 0.1 13.6 24.5 5.2 33.8 0.5 25.8 25.2 14.5 0.4 0.5 24.2 21.6 5.1 0.9 17.2 0.4 10.7 1.0 16.3 0.1 8.8 4.6 26.2 27.6 0.9 8.3 5.5 2.1 0.4 0.4 8.9 34.2 17.6 81.3 9.4 5.7 12.5 0.2 124.3 0.2 7.1 0.1 0.1 0.1 8.7 0.0 1.7 2.1 2.0 5.2 0.5 1.3 1.5 2.8 0.6 0.2 0.1 0.2 2.6 1.1 90.3 111.6 67.4 112.7 107.0 87.2 123.0 74.0 118.5 69.6 80.5 96.2 7.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 57.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 BMP4 BMP2B ENSG00000125378 "Bone morphogenetic protein 4" P12644 14 53949736-53958761 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 47.3;Fibroblasts: 65.2;Hepatic stellate cells: 52.8;Pancreatic endocrine cells: 40.1;Skeletal myocytes: 51.0;Syncytiotrophoblasts: 34.8" "Cancer enhanced" "Detected in all" "colorectal cancer: 28.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 1.9" "Group enriched" "Detected in many" 12 "monocytes: 1.9;T-cells: 1.3" "Cell line enhanced" "Detected in many" "CACO-2: 120.1;CAPAN-2: 298.6;Hep G2: 326.0;OE19: 219.1;SuSa: 168.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006863, HPA066235" Uncertain "Secreted to blood" NA NA 162000000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "CAB006863: , HPA066235: AB_2685641" "unprognostic (1.30e-1)" "unprognostic (3.27e-2)" "unprognostic (1.29e-1)" "unprognostic (5.20e-3)" "unprognostic (3.39e-2)" "unprognostic (3.32e-1)" "unprognostic (2.78e-2)" "unprognostic (3.11e-1)" "unprognostic (3.45e-3)" "unprognostic (7.67e-2)" "unprognostic (2.45e-3)" "unprognostic (7.06e-2)" "unprognostic (1.58e-2)" "unprognostic (2.93e-3)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" "unprognostic (1.24e-1)" 14.0 13.4 3.0 6.1 3.2 0.1 13.4 7.0 4.5 21.0 32.4 25.6 17.0 8.9 2.5 12.9 9.7 14.4 16.3 3.1 2.8 9.0 4.2 13.4 9.6 3.6 3.3 23.8 3.4 2.7 4.7 44.4 3.9 21.9 28.9 2.7 10.5 18.7 11.5 15.3 19.2 9.0 3.2 6.5 23.8 2.0 3.9 3.4 8.5 17.7 4.2 27.4 23.5 4.7 15.6 40.0 2.1 1.8 0.5 0.4 0.6 7.9 34.0 20.1 15.5 120.1 298.6 0.0 97.2 0.1 2.2 73.2 8.6 1.0 10.7 4.1 5.9 0.2 8.3 326.0 19.4 0.0 1.0 0.0 2.8 9.5 0.5 61.1 59.3 6.8 0.0 0.3 9.7 6.9 5.3 0.3 13.9 219.1 3.4 0.2 10.5 0.3 28.5 1.3 0.1 0.3 0.0 1.1 0.9 168.2 38.8 1.5 2.9 0.6 87.1 0.3 1.4 0.2 0.1 1.0 0.1 0.1 4.3 0.0 0.6 0.0 0.1 1.1 0.0 0.0 0.9 0.2 0.1 0.0 1.3 0.4 0.0 0.0 1.9 0.0 0.0 0.3 3.0 3.2 7.0 4.5 3.1 2.8 3.6 3.3 3.9 3.2 3.9 4.7 7.6 9.6 7.3 1.0 0.6 27.5 4.0 16.1 47.3 0.3 8.0 10.4 5.7 14.3 6.0 5.5 0.0 29.3 0.1 1.0 3.9 5.5 2.5 0.7 18.9 18.2 0.0 2.7 1.3 0.2 18.9 65.2 0.5 0.7 1.3 0.9 52.8 2.0 3.7 0.0 0.4 5.3 2.0 0.6 5.9 1.0 10.5 0.4 3.6 1.9 0.0 0.5 0.0 1.0 0.3 40.1 4.0 1.5 0.1 2.3 0.6 2.4 5.8 1.5 0.0 51.0 10.5 1.4 2.2 7.5 17.5 34.8 1.0 1.4 4.0 1.4 BOK "BCL2L9, BOKL, MGC4631" ENSG00000176720 "BCL2 family apoptosis regulator BOK" Q9UMX3 2 241551424-241574131 "Plasma proteins, Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 218.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 100.8;Oligodendrocytes: 47.0;Proximal tubular cells: 41.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.3" "Lineage enhanced" "Detected in single" "T-cells: 2.3" "Cell line enhanced" "Detected in many" "TIME: 65.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (6.16e-2)" "unprognostic (3.01e-2)" "unprognostic (1.24e-3)" "unprognostic (6.30e-2)" "unprognostic (8.63e-2)" "unprognostic (1.33e-1)" "unprognostic (2.24e-3)" "unprognostic (1.16e-2)" "unprognostic (8.45e-2)" "unprognostic (2.33e-1)" "unprognostic (2.47e-2)" "unprognostic (2.27e-1)" "prognostic favorable (1.09e-9)" "unprognostic (9.48e-3)" "unprognostic (6.81e-2)" "unprognostic (2.46e-1)" "unprognostic (1.09e-1)" 90.6 7.1 88.4 6.2 138.6 0.4 37.7 110.4 110.3 15.6 51.0 38.0 8.1 34.2 16.3 29.5 18.1 22.7 6.3 77.0 87.8 20.5 97.0 20.1 3.7 146.6 120.6 9.9 16.3 3.8 4.7 5.7 127.1 28.5 5.0 1.2 11.8 25.5 2.6 20.0 9.4 20.4 98.5 6.5 21.5 7.7 115.4 1.1 11.0 3.2 3.4 34.9 18.6 218.8 36.0 8.8 15.7 36.2 26.3 15.6 4.4 28.6 11.3 36.9 37.9 16.2 14.6 0.1 9.7 51.0 9.0 32.9 1.7 28.9 13.8 0.1 0.3 0.1 9.3 42.2 21.8 0.2 1.3 15.9 29.2 15.5 4.4 27.8 44.6 2.4 6.4 0.1 36.7 46.0 0.2 0.2 9.9 40.0 26.8 0.4 25.9 0.2 24.2 0.9 14.0 5.4 13.2 8.5 23.3 18.3 24.4 1.3 65.0 0.1 52.8 0.7 3.2 0.1 0.1 0.1 0.1 0.0 2.1 0.0 0.0 0.0 2.3 0.0 0.2 0.0 0.7 1.0 0.0 0.0 0.0 1.1 0.0 0.7 0.0 0.0 0.0 0.6 88.4 138.6 110.4 110.3 77.0 87.8 146.6 120.6 127.1 98.5 115.4 218.8 22.5 6.4 32.1 0.3 0.5 7.1 11.5 8.6 5.2 0.2 19.4 10.5 10.2 32.9 6.3 11.0 0.0 2.0 2.5 5.8 15.6 23.2 0.2 6.6 17.6 15.6 11.4 5.3 0.8 11.1 10.5 10.9 5.6 14.4 0.0 2.6 12.5 100.8 0.7 0.0 1.5 3.7 2.0 4.7 1.2 1.5 6.2 0.7 1.8 4.7 0.0 3.9 6.2 7.5 47.0 27.7 2.8 10.5 0.9 26.3 7.1 41.9 1.5 1.3 0.0 11.7 11.2 0.3 8.2 19.8 12.8 6.2 1.6 3.4 6.1 15.1 BRIP1 "BACH1, FANCJ, OF" ENSG00000136492 "BRCA1 interacting protein C-terminal helicase 1" Q9BX63 17 61679139-61863528 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Helicase, Hydrolase" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.2;lymphoid tissue: 5.9;testis: 7.0" "Group enriched" "Detected in many" 12 "Early spermatids: 186.2;Late spermatids: 194.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 88.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005474 Approved Supported "Nucleoplasm,Nuclear membrane" NA Yes "Cluster 26: Non-specific - Mitochondria" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Nuclear membrane" "HPA005474: AB_2667333" "unprognostic (1.88e-1)" "unprognostic (1.55e-2)" "prognostic favorable (3.45e-5)" "unprognostic (6.85e-4)" "unprognostic (3.09e-1)" "prognostic favorable (3.62e-4)" "unprognostic (2.60e-3)" "unprognostic (5.60e-2)" "unprognostic (5.66e-3)" "unprognostic (6.71e-2)" "unprognostic (1.50e-3)" "unprognostic (2.75e-2)" "unprognostic (3.41e-12)" "unprognostic (1.19e-2)" "unprognostic (2.25e-1)" "unprognostic (3.96e-2)" "unprognostic (3.62e-3)" 0.3 0.3 0.8 1.7 0.6 7.2 0.9 1.3 0.9 0.4 0.0 1.7 2.0 0.8 0.4 1.5 0.3 0.6 0.1 0.5 0.2 0.3 1.6 0.4 2.8 0.3 0.0 1.1 0.3 0.1 0.0 0.8 0.4 0.4 1.9 0.5 0.4 0.2 0.1 2.0 1.9 0.9 0.0 0.7 0.9 7.0 0.2 5.9 0.3 0.1 3.3 0.7 0.6 0.8 26.6 9.4 25.0 14.1 0.9 2.1 5.5 23.6 13.3 24.6 31.8 9.5 8.0 14.9 5.2 4.9 7.7 9.2 12.8 4.5 33.3 3.8 15.8 15.5 14.4 10.5 0.2 20.3 8.8 0.6 0.4 20.2 5.1 3.4 5.0 14.8 11.6 10.5 14.4 88.9 32.5 6.7 5.3 5.9 7.3 19.7 50.1 7.1 3.0 12.8 10.0 24.2 9.4 3.0 3.3 9.1 8.3 7.3 4.5 36.9 26.5 13.5 26.6 6.3 13.3 16.6 7.3 9.3 8.8 1.0 0.1 0.4 0.1 0.0 0.1 0.5 0.3 0.1 0.1 0.6 0.4 0.2 0.3 0.1 0.1 0.1 1.0 0.1 0.8 0.6 1.3 0.9 0.5 0.2 0.3 0.0 0.4 0.0 0.2 0.8 0.2 0.0 0.5 1.0 1.6 2.3 1.3 0.8 0.6 0.3 1.1 1.8 0.6 0.0 4.0 0.0 0.0 2.0 2.0 1.8 0.0 0.3 186.2 0.7 1.7 0.8 0.0 7.4 4.6 0.2 3.0 2.0 2.0 1.6 0.0 15.5 0.4 3.4 1.7 0.0 3.3 1.8 0.0 0.8 1.1 194.1 1.2 1.0 3.6 2.8 0.6 0.2 1.0 1.5 1.0 0.8 0.1 1.2 4.8 0.4 1.4 0.2 0.8 0.2 0.0 2.5 1.8 12.1 6.0 2.9 0.4 0.3 2.3 2.1 4.7 0.7 C11orf1 FLJ23499 ENSG00000137720 "Chromosome 11 open reading frame 1" Q9H5F2 11 111878935-111885975 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 402.4;Late spermatids: 1147.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038410, HPA057519" Uncertain Enhanced Nucleoplasm NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA038410: AB_10672591, HPA057519: AB_2683454" "unprognostic (1.33e-2)" "unprognostic (1.61e-1)" "unprognostic (1.96e-1)" "prognostic favorable (9.32e-4)" "unprognostic (1.30e-1)" "unprognostic (1.42e-2)" "unprognostic (1.10e-1)" "unprognostic (1.14e-1)" "unprognostic (9.26e-2)" "unprognostic (3.23e-2)" "unprognostic (1.41e-2)" "unprognostic (2.86e-2)" "prognostic favorable (1.39e-4)" "unprognostic (3.76e-2)" "unprognostic (2.12e-1)" "unprognostic (1.97e-1)" "unprognostic (2.08e-1)" 21.5 37.0 25.9 10.4 29.0 18.1 49.2 26.4 36.1 20.5 24.6 26.3 20.4 17.2 64.2 24.0 28.6 19.6 33.0 26.1 27.5 70.3 54.9 16.3 15.1 26.1 26.7 28.0 48.0 39.9 28.4 9.4 26.5 27.4 26.4 22.3 33.0 26.8 16.2 34.8 21.4 14.9 25.7 11.6 30.6 61.2 27.1 20.3 41.1 21.1 17.8 22.7 18.4 27.0 25.1 31.9 40.3 44.6 45.6 34.3 42.0 13.5 34.2 10.9 13.8 54.5 45.6 91.9 63.5 23.2 31.4 28.9 16.5 50.2 17.0 40.6 23.4 30.9 6.9 42.0 28.6 45.7 20.9 63.8 76.9 39.0 74.4 48.4 13.5 96.2 45.3 66.8 36.9 25.0 62.2 70.8 46.3 86.8 48.0 31.5 42.0 127.6 69.4 46.0 36.3 34.1 8.7 31.5 31.3 38.4 63.1 31.8 11.7 40.2 28.8 17.6 19.1 38.8 61.2 136.7 20.3 53.1 24.9 6.5 7.4 9.0 13.0 14.6 24.9 26.0 22.0 17.0 11.1 17.7 34.5 26.5 1.7 16.7 10.1 32.8 17.6 10.2 25.9 29.0 26.4 36.1 26.1 27.5 26.1 26.7 26.5 25.7 27.1 27.0 14.3 25.6 19.8 3.6 22.6 23.7 67.5 60.6 71.2 8.6 56.5 79.6 57.6 28.6 43.4 35.0 6.2 28.9 17.3 15.1 201.5 21.8 402.4 30.5 17.3 15.3 26.4 26.3 3.5 27.2 22.5 16.5 22.4 22.6 29.2 23.3 11.0 43.4 23.0 15.2 4.7 39.8 28.5 7.9 11.4 1147.2 27.4 14.3 24.9 3.7 19.3 43.5 20.6 1.0 3.7 18.9 22.3 24.5 41.9 36.4 40.6 197.9 44.4 15.5 19.7 10.8 17.0 54.4 30.9 53.4 29.5 21.1 22.6 49.2 44.4 72.7 C11orf52 "FLJ25219, MGC14839" ENSG00000149300 "Chromosome 11 open reading frame 52" Q96A22 11 111918032-111926871 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 2.8;Breast glandular cells: 3.3;Cholangiocytes: 2.8;Endometrial ciliated cells: 3.1;Gastric mucus-secreting cells: 4.1;Respiratory ciliated cells: 6.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 17.7;CAPAN-2: 23.5;Hep G2: 18.2;MCF7: 17.6;RPTEC TERT1: 27.1;SK-BR-3: 22.9;T-47d: 76.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038387, HPA038388" Uncertain Enhanced "Cell Junctions" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Cell Junctions" "HPA038387: AB_10670167, HPA038388: AB_2675987" "unprognostic (1.30e-2)" "unprognostic (1.13e-1)" "unprognostic (5.84e-4)" "unprognostic (1.48e-4)" "unprognostic (2.57e-1)" "unprognostic (8.04e-2)" "unprognostic (6.77e-2)" "unprognostic (2.07e-2)" "unprognostic (2.26e-1)" "unprognostic (2.77e-1)" "unprognostic (3.80e-1)" "unprognostic (5.38e-4)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "unprognostic (3.03e-1)" 3.3 0.7 1.0 0.4 0.9 0.0 25.9 4.1 1.3 3.8 2.2 5.2 10.4 2.3 23.7 6.4 17.7 12.3 3.2 0.9 0.9 43.9 22.8 9.7 0.1 1.1 1.0 1.5 25.8 30.8 16.4 10.1 1.7 15.4 6.2 0.1 26.8 10.2 9.3 9.7 9.2 0.8 1.1 0.9 20.9 1.0 1.1 1.0 20.1 8.3 1.3 4.6 3.2 1.5 4.3 0.0 0.0 0.0 2.9 0.4 17.7 1.0 0.8 0.1 0.0 6.8 23.5 0.0 10.6 2.3 0.0 5.4 0.0 1.4 0.1 0.0 0.7 0.0 0.5 18.2 0.0 0.0 0.0 0.3 5.2 0.0 0.2 0.2 1.0 0.0 0.0 0.0 1.5 17.6 0.0 0.2 0.1 12.5 1.8 0.0 1.5 0.0 27.1 15.6 1.2 0.0 0.0 22.9 0.0 2.4 76.5 1.6 2.0 0.5 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 4.1 1.3 0.9 0.9 1.1 1.0 1.7 1.1 1.1 1.5 0.0 6.4 2.8 0.0 0.0 0.1 1.6 0.2 1.2 0.0 3.3 0.9 0.6 2.8 0.1 0.0 0.0 0.6 0.0 0.0 0.0 1.3 0.0 3.1 0.2 0.2 0.0 0.0 0.0 1.0 0.3 0.5 4.1 1.9 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 1.9 1.3 6.7 0.0 0.0 0.3 0.3 0.1 0.1 0.6 0.3 1.4 0.0 0.2 0.2 0.7 C11orf97 LINC01171 ENSG00000257057 "Chromosome 11 open reading frame 97" A0A1B0GVM6 11 94512461-94532123 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "fallopian tube: 19.1;testis: 18.2" "Group enriched" "Detected in some" 5 "Early spermatids: 239.3;Endometrial ciliated cells: 258.2;Respiratory ciliated cells: 109.3" "Cancer enhanced" "Detected in some" "endometrial cancer: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (3.62e-3)" "unprognostic (1.29e-1)" "unprognostic (1.22e-1)" "unprognostic (4.18e-1)" "unprognostic (4.70e-1)" "unprognostic (9.64e-3)" "unprognostic (9.44e-3)" "unprognostic (3.86e-3)" 0.0 0.0 1.4 0.0 2.6 0.3 0.0 0.2 1.7 1.2 4.0 0.0 0.0 0.5 0.1 0.0 19.1 0.1 0.0 1.5 1.1 0.9 1.3 2.5 0.0 2.2 2.5 0.0 0.5 0.0 0.2 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 18.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 2.6 0.2 1.7 1.5 1.1 2.2 2.5 1.6 1.9 1.5 1.5 0.0 3.2 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 11.2 0.0 0.0 0.3 0.0 0.1 0.0 0.4 239.3 258.2 1.4 0.6 0.0 0.0 3.4 0.2 0.0 0.5 0.0 3.2 0.0 0.0 0.0 4.5 0.1 0.0 2.0 0.0 0.0 0.0 0.0 34.4 1.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 1.9 0.0 0.0 0.0 18.1 109.3 0.0 0.0 0.0 0.0 37.9 9.6 0.0 0.0 0.0 0.5 0.0 0.0 0.1 C1orf115 "FLJ14146, RDD1" ENSG00000162817 "Chromosome 1 open reading frame 115" Q9H7X2 1 220690363-220699153 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 120.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 109.8;Hepatocytes: 121.3;Proximal enterocytes: 255.7;Syncytiotrophoblasts: 183.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Hep G2: 62.4;HUVEC TERT2: 49.7;TIME: 93.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 45: Enterocytes - Digestion" "unprognostic (1.60e-1)" "unprognostic (4.40e-2)" "unprognostic (5.16e-2)" "prognostic favorable (6.52e-4)" "unprognostic (1.31e-1)" "unprognostic (3.93e-2)" "unprognostic (2.03e-1)" "unprognostic (5.69e-3)" "unprognostic (8.65e-2)" "prognostic favorable (5.12e-5)" "unprognostic (3.11e-1)" "unprognostic (1.33e-1)" "unprognostic (1.74e-2)" "unprognostic (4.24e-1)" "unprognostic (4.54e-2)" "unprognostic (9.21e-3)" "unprognostic (1.07e-1)" 50.0 6.8 32.3 6.8 43.4 0.3 28.4 10.8 45.8 14.8 17.3 30.9 112.4 12.5 21.3 5.7 14.4 10.3 18.9 47.5 11.5 52.8 101.4 23.4 8.5 13.1 10.5 17.9 12.1 20.5 17.5 70.2 13.5 31.1 23.3 8.9 74.1 10.6 14.6 9.1 120.9 11.8 10.0 50.0 22.4 7.2 15.9 3.8 16.5 19.3 9.5 6.9 7.2 25.9 1.6 7.3 0.5 10.1 0.0 0.0 29.0 2.0 8.1 4.2 18.3 7.3 7.6 0.0 3.1 0.6 8.5 0.2 16.9 3.4 3.8 0.0 16.9 0.2 1.5 62.4 9.4 0.0 0.2 1.3 5.7 0.3 2.1 0.0 49.7 0.0 4.7 0.0 0.3 6.7 0.0 0.5 12.3 20.4 5.2 0.0 0.1 0.6 9.0 9.8 5.3 7.4 0.0 12.3 30.9 17.5 20.0 0.4 93.6 0.0 0.1 0.3 1.7 1.1 0.0 0.0 0.2 0.0 1.5 0.0 0.2 0.0 0.2 0.0 0.1 0.5 0.2 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 32.3 43.4 10.8 45.8 47.5 11.5 13.1 10.5 13.5 10.0 15.9 25.9 76.7 3.2 6.7 1.6 5.8 3.4 4.2 1.4 1.8 17.3 29.8 20.4 19.5 17.2 5.1 31.3 6.2 74.4 0.9 109.8 39.2 9.7 1.5 7.6 1.3 51.5 8.4 8.0 20.7 16.6 68.2 5.6 2.0 11.7 0.0 59.0 18.9 121.3 6.4 0.0 2.0 25.6 6.1 4.7 2.7 2.8 3.1 1.4 8.8 5.6 4.8 10.4 0.0 0.0 1.4 13.9 55.5 19.2 0.0 11.0 255.7 58.2 1.9 3.9 0.0 2.1 4.6 0.5 5.5 0.8 1.7 183.9 1.2 54.9 25.1 2.6 C1orf210 "MGC52423, TEMP" ENSG00000253313 "Chromosome 1 open reading frame 210" Q8IVY1 1 43281877-43285617 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 43.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 125.9;Paneth cells: 100.8;Proximal enterocytes: 128.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 14 "basophil: 2.2" "Lineage enriched" "Detected in single" 14 "granulocytes: 2.2" "Cell line enhanced" "Detected in some" "A-431: 12.1;BEWO: 13.0;CACO-2: 12.6;CAPAN-2: 39.8;OE19: 33.1;SK-BR-3: 13.8;T-47d: 15.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA013788 Uncertain Uncertain "Nucleoli,Nucleoli rim" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli, Nucleoli rim" "HPA013788: AB_1845637" "unprognostic (1.38e-2)" "unprognostic (1.08e-1)" "unprognostic (1.84e-1)" "unprognostic (1.20e-1)" "unprognostic (1.92e-1)" "unprognostic (1.42e-1)" "unprognostic (1.66e-1)" "unprognostic (1.06e-2)" "unprognostic (1.98e-1)" "unprognostic (3.54e-2)" "unprognostic (2.74e-1)" "unprognostic (2.01e-2)" "prognostic favorable (0.00e+0)" "unprognostic (7.57e-3)" "unprognostic (3.94e-1)" "unprognostic (1.00e-1)" "unprognostic (1.61e-2)" 0.2 0.1 0.3 2.9 0.3 0.2 14.5 0.7 0.5 8.2 0.3 32.4 43.9 1.3 13.0 17.0 6.1 9.9 0.1 0.3 0.2 21.8 6.2 9.0 0.1 0.3 0.4 0.1 22.8 10.3 8.4 1.6 0.4 8.1 30.2 0.5 19.5 3.8 0.0 16.2 38.7 1.2 0.2 0.1 29.1 0.3 0.3 1.0 16.9 0.0 2.3 3.2 8.1 0.8 12.1 0.0 0.0 0.1 0.0 0.0 13.0 0.0 0.0 0.0 0.0 12.6 39.8 0.0 0.3 0.0 0.0 9.0 0.0 5.6 0.0 0.0 0.0 0.1 0.2 0.7 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.0 0.0 0.2 0.1 33.1 0.0 0.1 0.1 0.4 1.0 7.8 4.6 0.3 0.1 13.8 0.0 2.1 15.2 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.3 0.3 0.7 0.5 0.3 0.2 0.3 0.4 0.4 0.2 0.3 0.8 0.1 22.4 16.1 0.3 0.6 1.1 6.2 11.5 2.8 0.0 22.4 12.8 0.0 28.6 13.8 22.0 0.0 12.9 0.0 125.9 29.4 21.3 0.1 8.5 1.4 0.2 33.6 0.0 0.0 33.7 3.9 0.2 25.5 14.2 0.0 0.0 0.0 1.2 0.7 0.0 0.0 42.4 8.2 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.3 100.8 0.0 0.0 6.6 128.1 39.6 7.3 0.0 0.0 0.0 0.7 0.3 0.0 8.9 2.6 4.7 0.3 0.0 37.0 8.8 C1QA ENSG00000173372 "Complement C1q A chain" P02745 1 22636628-22639678 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 1092.6" "Group enriched" "Detected in many" 9 "Hofbauer cells: 1663.2;Kupffer cells: 5007.4;Macrophages: 1874.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39 "intermediate monocyte: 226.1;non-classical monocyte: 181.7" "Lineage enriched" "Detected in many" 60 "monocytes: 226.1" "Cell line enhanced" "Detected in some" "HMC-1: 2.3;NB-4: 1.4;RPMI-8226: 7.1;SCLC-21H: 3.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002350, CAB009823" Supported "Secreted to blood" NA NA 2700000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009823: AB_2228238, HPA002350: AB_1078552" "unprognostic (1.97e-1)" "unprognostic (1.14e-2)" "unprognostic (1.98e-3)" "unprognostic (3.07e-2)" "unprognostic (6.10e-2)" "unprognostic (2.60e-1)" "unprognostic (1.16e-1)" "unprognostic (2.13e-1)" "unprognostic (1.67e-2)" "unprognostic (1.99e-1)" "unprognostic (4.42e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (1.58e-6)" "unprognostic (1.54e-1)" "unprognostic (2.11e-3)" "unprognostic (2.75e-2)" "unprognostic (7.30e-2)" 375.1 235.6 86.6 134.0 85.6 53.9 95.9 85.8 135.3 75.8 120.0 142.8 172.3 43.1 26.0 58.3 75.6 172.4 74.8 82.9 93.7 56.2 208.8 404.3 532.3 126.7 110.1 37.5 34.3 26.2 46.3 256.3 110.3 47.1 120.2 4.1 48.1 54.6 14.8 21.8 190.1 195.0 107.5 1092.6 90.8 38.2 109.4 100.3 36.5 49.3 68.0 257.5 30.4 131.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.4 0.3 0.0 0.0 0.5 0.2 7.1 0.0 0.0 3.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.4 0.1 0.8 0.0 0.0 0.1 0.1 0.0 0.1 5.2 0.1 0.1 226.1 0.0 0.0 0.1 0.1 3.7 0.0 0.0 0.0 0.5 0.3 181.7 0.0 0.0 9.7 86.6 85.6 85.8 135.3 82.9 93.7 126.7 110.1 110.3 107.5 109.4 131.6 17.4 35.3 55.8 0.0 19.0 18.4 2.3 0.0 2.2 0.4 5.1 24.6 8.9 37.1 18.0 0.0 0.0 8.7 2.7 0.5 0.0 0.0 4.5 0.2 0.5 46.0 1.8 41.0 0.0 0.2 11.3 9.6 0.0 0.2 21.5 0.2 76.1 26.2 1663.2 0.0 0.0 0.1 0.0 5007.4 291.4 9.9 13.1 1874.2 26.6 20.6 16.7 0.3 0.0 0.0 0.1 0.0 0.1 0.4 2.8 1.3 0.1 1.1 15.3 0.8 78.9 7.4 4.6 0.7 2.1 4.2 16.8 18.2 11.8 0.0 0.2 1.3 C1QB ENSG00000173369 "Complement C1q B chain" 1 22652762-22661637 "Human disease related genes, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "lung: 546.4;lymphoid tissue: 990.2" "Group enriched" "Detected in many" 28 "Hofbauer cells: 1451.0;Kupffer cells: 4559.7;Macrophages: 1747.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 71 "intermediate monocyte: 140.6;non-classical monocyte: 101.2" "Lineage enriched" "Detected in many" 85 "monocytes: 140.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052116 Approved "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA052116: AB_2681735" "unprognostic (1.42e-1)" "unprognostic (3.36e-2)" "unprognostic (5.61e-3)" "unprognostic (8.20e-2)" "unprognostic (5.93e-2)" "unprognostic (4.09e-1)" "unprognostic (1.25e-1)" "unprognostic (2.35e-1)" "unprognostic (2.87e-2)" "unprognostic (2.21e-1)" "unprognostic (2.63e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (9.58e-6)" "unprognostic (4.14e-2)" "unprognostic (7.76e-3)" "unprognostic (4.83e-2)" "unprognostic (2.35e-2)" 439.2 229.0 95.8 149.4 94.2 53.5 87.1 97.2 148.7 65.4 132.6 162.0 186.0 27.7 26.4 63.0 50.5 194.9 62.6 89.8 107.7 18.3 243.4 546.4 514.6 161.0 143.3 39.6 40.0 28.5 1.8 249.2 138.4 28.0 146.0 7.8 44.9 51.2 5.3 6.1 186.1 261.4 138.2 990.2 88.0 39.9 142.2 72.0 23.6 38.6 58.4 255.8 1.1 185.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.8 0.4 0.0 0.0 0.5 0.3 0.6 0.0 0.0 0.5 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.8 0.0 0.1 0.1 0.0 0.2 0.0 1.7 0.0 0.0 140.6 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.4 0.8 101.2 0.0 0.0 5.3 95.8 94.2 97.2 148.7 89.8 107.7 161.0 143.3 138.4 138.2 142.2 185.8 13.8 12.8 22.1 0.0 17.1 6.2 2.1 0.0 1.8 1.2 4.9 23.1 5.5 24.3 10.5 3.7 0.0 6.6 2.7 0.6 0.0 0.0 3.3 0.1 0.2 65.9 0.0 32.8 0.1 0.0 9.6 5.9 0.0 0.1 11.4 0.1 52.1 26.0 1451.0 0.0 0.1 0.0 0.0 4559.7 92.1 7.8 8.4 1747.2 0.0 34.7 5.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 2.3 1.0 0.3 1.1 3.6 3.9 59.2 4.0 3.2 0.4 0.9 5.7 4.5 9.6 6.1 0.2 0.0 1.5 C1QC C1QG ENSG00000159189 "Complement C1q C chain" P02747 1 22643633-22648110 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 950.7" "Group enriched" "Detected in many" 7 "Hofbauer cells: 1356.5;Kupffer cells: 2134.6;Macrophages: 1040.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "intermediate monocyte: 57.2" "Lineage enriched" "Detected in single" 541 "monocytes: 57.2" "Cell line enhanced" "Detected in some" "NB-4: 1.0;RPMI-8226: 2.6;U-266/70: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001471, CAB009828" Supported "Secreted to blood" NA NA 513000000 2100000000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009828: AB_2067541, HPA001471: AB_1078553" "unprognostic (2.97e-1)" "unprognostic (6.80e-2)" "unprognostic (2.40e-2)" "unprognostic (1.84e-1)" "unprognostic (7.40e-2)" "unprognostic (2.38e-1)" "unprognostic (1.98e-1)" "unprognostic (1.40e-1)" "unprognostic (1.66e-2)" "unprognostic (7.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (1.06e-1)" "unprognostic (1.63e-3)" "unprognostic (2.21e-2)" "unprognostic (3.73e-2)" 285.2 196.0 60.1 159.7 58.6 43.5 70.5 64.8 97.1 51.9 90.6 133.2 179.9 36.3 13.5 55.3 67.4 155.4 58.6 54.9 75.5 41.2 169.6 290.8 370.2 124.7 105.4 32.1 37.5 22.1 39.6 204.9 105.0 37.8 91.3 3.9 51.6 44.5 12.9 18.3 195.7 164.7 100.4 950.7 94.8 33.9 106.0 75.7 29.2 31.8 50.7 191.8 24.6 159.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 1.0 0.2 0.0 0.0 0.6 0.2 2.6 0.0 0.0 0.4 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 1.0 0.0 0.1 0.1 0.1 0.0 0.0 1.3 0.0 0.0 57.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.4 0.0 0.0 1.2 60.1 58.6 64.8 97.1 54.9 75.5 124.7 105.4 105.0 100.4 106.0 159.3 13.4 6.4 5.2 0.3 13.7 8.9 1.1 0.0 2.8 0.6 4.9 24.5 1.6 15.7 3.1 0.0 0.0 5.8 2.3 0.4 0.0 0.0 3.2 0.0 0.1 34.5 0.0 27.2 0.0 0.2 9.5 4.4 0.0 0.1 5.1 0.1 25.4 6.6 1356.5 0.0 0.1 0.1 0.0 2134.6 202.4 3.6 6.2 1040.7 7.2 29.0 23.6 0.4 0.0 0.0 0.0 0.0 1.1 1.2 0.9 0.4 0.0 0.4 0.7 0.6 46.0 2.5 1.8 0.4 0.8 3.3 6.5 9.9 3.5 0.0 0.0 0.7 C1QTNF7 CTRP7 ENSG00000163145 "C1q and TNF related 7" Q9BXJ2 4 15339818-15446167 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 15.8;Fibroblasts: 32.3;Leydig cells: 22.7;Peritubular cells: 31.6;Skeletal myocytes: 15.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 4.2;ASC TERT1: 2.8;HSkMC: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007055, HPA051797, HPA055392" Uncertain Approved Vesicles "Secreted to blood" NA NA 238000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB007055: , HPA051797: AB_2681614, HPA055392: AB_2732596" "unprognostic (6.61e-2)" "unprognostic (4.50e-2)" "unprognostic (6.16e-2)" "unprognostic (6.50e-4)" "unprognostic (1.24e-1)" "unprognostic (4.98e-3)" "unprognostic (2.31e-2)" "unprognostic (7.69e-3)" "unprognostic (7.61e-2)" "unprognostic (1.13e-1)" "unprognostic (2.41e-1)" "unprognostic (1.38e-1)" "unprognostic (2.97e-4)" "unprognostic (3.01e-3)" "unprognostic (8.31e-2)" "unprognostic (7.56e-3)" "unprognostic (7.28e-3)" 7.8 1.4 1.2 1.6 1.2 0.0 4.7 1.2 2.6 23.1 0.0 8.6 1.2 16.5 10.2 6.0 6.3 14.0 7.0 0.8 1.8 5.5 1.2 10.8 1.2 1.1 1.8 20.9 0.8 0.1 1.1 7.2 0.9 9.5 4.2 0.1 2.5 3.2 0.6 3.2 3.8 12.0 0.6 9.7 9.0 1.7 1.8 0.4 3.8 6.6 0.5 10.3 10.3 1.3 0.0 0.0 0.0 0.0 4.2 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 1.2 1.2 2.6 0.8 1.8 1.1 1.8 0.9 0.6 1.8 1.3 1.2 0.0 0.0 1.0 0.0 3.6 0.0 0.0 0.0 15.8 0.1 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.1 0.2 6.5 0.5 0.0 0.0 1.0 0.0 0.3 32.3 0.0 0.6 0.0 2.0 0.0 0.0 0.1 1.7 4.4 0.0 0.0 0.0 3.2 0.5 22.7 0.3 5.4 6.5 0.0 0.3 0.0 2.5 0.7 0.0 0.0 31.6 0.2 0.1 0.0 2.8 0.0 1.2 6.6 15.2 9.9 0.0 0.1 0.6 3.0 0.0 0.7 5.7 0.0 0.1 C1RL "C1r-LP, C1RL1" ENSG00000139178 "Complement C1r subcomponent like" Q9NZP8 12 7089587-7109238 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 141.9" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 54.2;Hepatocytes: 140.0;Leydig cells: 55.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 5.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 38.2;HSkMC: 43.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA011338, CAB026172" Supported "Secreted to blood" NA NA 5500000000 15000000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "CAB026172: , HPA011338: AB_1847111" "prognostic favorable (7.92e-4)" "unprognostic (7.76e-2)" "unprognostic (3.91e-3)" "unprognostic (5.25e-3)" "unprognostic (2.92e-3)" "unprognostic (9.60e-2)" "unprognostic (2.75e-3)" "unprognostic (7.76e-2)" "unprognostic (1.22e-1)" "unprognostic (4.34e-1)" "unprognostic (9.58e-3)" "unprognostic (1.57e-1)" "prognostic unfavorable (1.52e-7)" "unprognostic (1.75e-1)" "unprognostic (5.74e-2)" "unprognostic (2.52e-1)" "unprognostic (2.26e-3)" 38.3 72.5 3.4 12.2 3.3 8.2 36.5 2.6 3.1 38.6 7.1 28.8 7.6 30.2 6.3 17.5 40.8 11.7 18.4 2.7 4.0 20.1 141.9 33.1 9.5 7.4 5.0 49.4 36.7 8.0 17.5 5.1 4.4 29.3 8.7 1.5 33.7 6.9 11.0 18.1 26.3 13.7 3.7 32.3 27.5 6.1 3.9 6.9 21.7 6.0 7.7 38.1 27.5 3.3 3.0 7.7 0.7 7.9 22.4 38.2 5.4 4.9 22.7 5.0 14.8 4.9 13.4 1.3 4.1 4.1 5.0 6.4 2.1 8.1 1.9 12.0 0.4 4.8 8.5 11.4 18.7 1.0 21.9 43.1 15.7 3.0 9.3 23.3 5.3 2.8 3.6 3.1 3.1 0.1 0.7 0.9 1.4 0.6 0.2 2.7 0.0 1.0 13.1 13.2 0.6 1.7 16.7 2.0 2.8 1.3 1.9 4.1 5.0 4.3 7.7 4.9 0.9 2.3 1.0 0.2 8.1 3.4 2.0 3.8 0.7 4.0 0.6 1.1 0.3 1.2 0.6 0.5 0.8 0.5 0.4 0.4 5.4 0.3 1.3 0.4 0.4 0.4 3.4 3.3 2.6 3.1 2.7 4.0 7.4 5.0 4.4 3.7 3.9 3.3 11.0 16.0 38.6 7.5 8.4 3.8 15.4 16.4 25.6 0.5 15.6 14.5 2.6 30.0 24.6 5.5 2.1 0.2 7.3 8.3 1.9 36.3 0.1 7.9 22.6 14.6 4.2 7.8 10.2 54.2 0.4 29.0 27.5 10.4 3.8 13.8 25.0 140.0 3.6 0.0 1.3 7.7 10.2 10.0 4.9 3.0 55.6 10.2 3.6 14.0 13.3 4.0 21.6 2.0 0.4 25.8 9.7 20.3 8.0 10.2 9.3 8.2 15.9 1.1 0.0 11.8 10.1 0.6 0.9 8.5 3.1 0.1 9.7 13.6 9.5 8.7 C1S ENSG00000182326 "Complement C1s" P09871 12 6988259-7071032 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 2915.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 687.0;Hepatocytes: 2795.1;Leydig cells: 1193.2;Peritubular cells: 640.1" "Cancer enhanced" "Detected in all" "liver cancer: 276.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "neutrophil: 2.2" "Lineage enriched" "Detected in single" 18 "granulocytes: 2.2" "Cell line enhanced" "Detected in many" "ASC diff: 769.5;ASC TERT1: 1012.7;BJ hTERT+: 336.1;HSkMC: 540.2" "Not detected" "Not detected" "CAB016722, HPA018852" Supported Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 93000000000 14000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm Cytosol "CAB016722: , HPA018852: AB_1847112" "unprognostic (2.72e-3)" "unprognostic (7.31e-2)" "unprognostic (9.37e-2)" "unprognostic (1.39e-2)" "unprognostic (1.05e-2)" "unprognostic (9.63e-2)" "prognostic favorable (7.73e-4)" "unprognostic (6.38e-2)" "unprognostic (1.16e-1)" "unprognostic (6.14e-2)" "unprognostic (1.57e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (7.44e-15)" "unprognostic (2.02e-2)" "unprognostic (5.68e-3)" "unprognostic (1.19e-2)" "unprognostic (5.39e-2)" 416.4 136.1 26.4 207.7 28.5 1.7 252.5 27.1 43.1 309.2 36.7 192.4 84.6 209.0 147.2 152.9 315.4 543.8 191.5 25.4 34.8 60.2 2915.2 224.9 209.2 44.3 31.7 485.9 62.1 21.8 33.1 52.9 31.2 174.4 215.2 9.7 96.9 139.1 57.0 104.1 154.2 251.8 30.9 168.5 150.1 90.0 30.9 88.1 139.0 154.7 192.5 455.7 189.8 31.3 0.2 18.6 1.2 10.2 769.5 1012.7 4.5 143.3 336.1 74.7 135.7 0.9 2.0 0.5 19.7 179.6 20.2 1.1 0.3 2.1 6.7 0.7 0.7 0.5 5.6 48.2 230.3 1.8 0.9 540.2 2.8 60.2 4.4 94.2 0.1 0.2 0.4 0.1 9.9 0.0 0.4 1.6 10.3 0.0 0.6 0.2 1.1 1.5 3.1 2.5 0.8 0.9 86.6 1.8 2.1 17.4 0.1 0.0 0.5 34.2 2.6 133.8 0.2 0.6 0.5 0.8 73.6 1.2 2.5 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 26.4 28.5 27.1 43.1 25.4 34.8 44.3 31.7 31.2 30.9 30.9 31.3 37.6 16.0 41.0 9.4 5.7 76.2 18.9 22.2 23.9 0.9 4.5 15.4 21.5 171.6 15.5 3.7 0.0 3.7 0.7 0.1 1.9 285.2 6.6 8.7 272.4 30.6 0.0 112.2 2.9 42.9 2.5 687.0 11.2 7.3 5.1 25.7 93.5 2795.1 8.1 5.0 1.7 0.0 2.0 62.8 103.7 29.9 1193.2 6.4 88.9 19.7 1.0 15.2 0.0 1.5 0.6 31.7 0.1 640.1 1.8 9.7 0.0 7.1 4.6 1.1 138.1 34.9 127.6 6.3 5.3 6.3 53.8 2.6 12.8 30.7 0.2 5.2 C3 "ARMD9, C3a, C3b, CPAMD1" ENSG00000125730 "Complement C3" P01024 19 6677704-6730562 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Fatty acid metabolism, Immunity, Inflammatory response, Innate immunity, Lipid metabolism" "Age-related macular degeneration, Disease variant, FDA approved drug targets, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "liver: 4761.3" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 4512.2" "Cancer enriched" "Detected in all" 5 "liver cancer: 1213.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "non-classical monocyte: 13.3" "Lineage enriched" "Detected in many" 4 "monocytes: 13.3" "Group enriched" "Detected in many" 7 "BJ hTERT+: 357.8;EFO-21: 738.6;Hep G2: 795.3;HSkMC: 534.8;SiHa: 209.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003563, CAB004209, HPA020432" Enhanced "Secreted to blood" NA NA 1260000000000 200000000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB004209: AB_627277, HPA003563: AB_1847117, HPA020432: AB_1847118" "unprognostic (3.26e-3)" "unprognostic (3.91e-1)" "unprognostic (3.92e-1)" "unprognostic (5.98e-3)" "unprognostic (3.31e-1)" "unprognostic (1.04e-1)" "prognostic favorable (8.11e-4)" "unprognostic (1.99e-1)" "unprognostic (9.26e-2)" "unprognostic (5.80e-2)" "unprognostic (8.12e-3)" "unprognostic (5.48e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (2.63e-2)" "unprognostic (2.49e-2)" "unprognostic (6.03e-3)" "unprognostic (3.88e-1)" 585.2 286.5 46.0 194.3 53.7 1.5 213.9 47.8 46.0 237.5 31.5 128.9 22.9 82.9 41.1 76.4 350.3 354.9 221.6 36.5 81.8 51.4 4761.3 176.0 68.2 143.3 99.2 228.1 182.7 17.9 21.8 17.7 116.4 35.4 76.5 11.7 155.6 57.4 36.6 51.4 156.4 123.0 89.9 7.1 107.9 41.1 103.4 34.1 92.4 52.0 126.4 363.3 101.3 121.9 65.0 23.0 0.0 0.1 10.8 36.0 74.7 5.2 357.8 6.8 12.6 3.6 49.5 1.9 738.6 0.3 54.2 46.6 0.2 43.1 6.9 24.0 0.5 3.1 31.2 795.3 16.3 6.2 9.1 534.8 12.8 60.8 27.3 9.5 0.0 0.0 2.1 0.8 0.2 1.0 0.6 1.6 1.5 0.7 0.1 0.4 5.0 0.3 32.1 6.2 0.5 0.5 209.5 0.1 0.5 0.1 17.2 8.8 3.5 5.7 7.4 4.8 3.6 1.6 4.8 4.5 75.1 4.5 0.3 1.7 1.3 0.6 0.3 2.5 0.2 0.5 0.2 0.1 0.7 0.5 0.2 0.2 3.0 1.3 13.3 0.5 0.1 0.9 46.0 53.7 47.8 46.0 36.5 81.8 143.3 99.2 116.4 89.9 103.4 121.9 36.4 76.9 473.9 0.7 29.4 27.5 14.7 141.5 0.6 0.7 19.5 23.4 14.5 783.5 422.5 16.5 0.0 1.4 2.0 0.2 5.9 494.1 45.9 23.0 63.5 26.2 0.0 209.9 0.4 136.7 1.4 482.2 17.9 57.7 5.1 0.1 124.9 4512.2 34.4 0.0 0.5 0.9 20.3 164.5 44.8 97.5 226.2 45.1 35.6 70.3 14.6 1.2 0.0 0.5 0.6 376.4 0.2 10.9 3.9 13.3 1.9 53.6 177.5 4.6 6.6 20.1 49.1 4.0 7.7 5.2 21.9 2.7 15.0 0.1 0.4 38.2 C4BPA C4BP ENSG00000123838 "Complement component 4 binding protein alpha" P04003 1 207104233-207144972 "Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 1918.6" "Group enriched" "Detected in many" 14 "Alveolar cells type 1: 493.6;Alveolar cells type 2: 660.8;Hepatocytes: 1020.8" "Cancer enriched" "Detected in many" 7 "liver cancer: 434.8" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 137 "neutrophil: 29.5" "Lineage enriched" "Detected in single" 137 "granulocytes: 29.5" "Cell line enriched" "Detected in some" 5 "Hep G2: 37.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000926, HPA001578" Enhanced "Secreted to blood" NA NA 30800000000 28000000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA000926: AB_1078355, HPA001578: AB_1078354" "unprognostic (3.85e-4)" "unprognostic (9.07e-2)" "unprognostic (2.06e-1)" "prognostic favorable (6.37e-5)" "unprognostic (3.58e-2)" "unprognostic (2.41e-1)" "prognostic favorable (2.24e-4)" "unprognostic (3.64e-2)" "unprognostic (1.94e-1)" "unprognostic (5.90e-4)" "unprognostic (4.47e-2)" "unprognostic (2.58e-1)" "unprognostic (5.51e-7)" "unprognostic (9.74e-2)" "unprognostic (2.52e-2)" "unprognostic (6.92e-2)" "unprognostic (2.66e-1)" 1.4 0.7 0.4 2.5 0.2 0.1 4.5 0.7 0.2 6.3 0.0 1.7 0.0 4.5 0.0 0.1 1.0 3.2 0.2 0.1 0.7 0.6 1918.6 173.3 0.3 0.4 0.2 1.5 9.6 0.2 0.1 0.7 0.5 0.1 0.8 0.0 1.1 0.0 0.0 0.0 0.8 0.1 0.1 1.2 0.4 0.3 0.3 0.0 0.1 0.0 1.1 0.1 0.0 0.4 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 37.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 7.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.5 0.0 0.2 0.0 0.0 0.0 0.4 0.2 0.7 0.2 0.1 0.7 0.4 0.2 0.5 0.1 0.3 0.4 0.0 493.6 660.8 0.0 3.7 0.0 0.0 0.2 0.0 0.0 2.7 0.4 0.2 41.5 22.5 0.0 0.0 0.0 0.0 3.2 0.0 11.2 0.3 18.0 7.6 1.9 0.0 21.5 0.7 18.7 0.0 1.1 0.0 48.8 3.8 0.0 22.1 1020.8 0.2 0.0 1.4 0.3 0.0 39.2 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 5.6 32.0 0.0 0.0 0.3 0.1 0.1 3.6 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 3.9 16.7 0.2 1.4 C6 ENSG00000039537 "Complement C6" P13671 5 41142116-41261438 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" "Complement pathway, Cytolysis, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "liver: 665.9" "Cell type enhanced" "Detected in some" "Cholangiocytes: 127.2;Hepatocytes: 376.9;Late spermatids: 54.8;Leydig cells: 120.2;Respiratory ciliated cells: 58.0" "Group enriched" "Detected in many" 7 "liver cancer: 49.0;pancreatic cancer: 12.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "ASC diff: 4.5;ASC TERT1: 6.2;HSkMC: 16.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA043823, CAB069427" Enhanced "Secreted to blood" NA NA 45000000000 9200000000 "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "CAB069427: AB_1614336, HPA043823: AB_10960262" "unprognostic (9.79e-2)" "unprognostic (1.96e-2)" "unprognostic (5.94e-3)" "unprognostic (3.02e-2)" "unprognostic (1.67e-1)" "unprognostic (1.18e-1)" "unprognostic (1.12e-3)" "unprognostic (4.66e-2)" "unprognostic (3.72e-2)" "unprognostic (1.53e-1)" "unprognostic (2.34e-1)" "unprognostic (3.04e-3)" "prognostic favorable (4.31e-4)" "unprognostic (2.69e-4)" "unprognostic (1.61e-1)" "unprognostic (1.40e-2)" "unprognostic (3.51e-2)" 12.8 1.1 0.2 0.0 0.2 0.0 5.4 0.2 0.1 0.8 1.6 0.8 0.9 0.4 0.9 0.3 43.9 12.0 57.1 0.2 0.6 4.4 665.9 3.2 0.4 0.0 1.7 6.2 42.7 0.1 0.7 2.8 0.2 0.9 0.6 0.0 0.9 0.6 0.6 0.6 1.4 0.9 0.1 0.3 2.2 4.2 0.8 0.6 2.0 0.7 0.5 0.9 0.6 0.6 0.0 0.0 0.0 0.0 4.5 6.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.1 0.2 0.6 0.0 1.7 0.2 0.1 0.8 0.6 0.8 0.0 0.0 0.7 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 20.9 127.2 7.5 0.0 0.0 0.0 0.1 0.3 0.0 9.3 11.3 37.5 0.8 0.9 0.0 8.0 1.4 0.4 0.0 6.7 0.0 0.7 0.0 0.1 5.0 376.9 0.0 0.0 2.7 1.0 0.0 9.7 0.3 54.8 120.2 0.2 0.0 0.0 0.0 0.0 0.0 1.0 1.3 0.5 1.3 0.4 0.0 0.0 11.6 0.8 58.0 0.0 0.0 0.2 0.4 0.4 0.1 0.0 0.0 0.0 0.4 0.5 0.6 0.0 C8orf82 MGC70857 ENSG00000213563 "Chromosome 8 open reading frame 82" Q6P1X6 8 144525733-144529132 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 138.9;Proximal tubular cells: 99.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "PC-3: 46.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB034331 Uncertain Approved Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "CAB034331: AB_1565393" "unprognostic (3.56e-1)" "unprognostic (1.28e-1)" "unprognostic (1.13e-1)" "unprognostic (1.63e-2)" "unprognostic (8.60e-2)" "unprognostic (6.31e-3)" "unprognostic (1.95e-1)" "unprognostic (4.57e-2)" "unprognostic (3.82e-1)" "unprognostic (1.22e-1)" "unprognostic (3.61e-1)" "unprognostic (4.09e-2)" "prognostic favorable (1.70e-5)" "unprognostic (5.72e-3)" "unprognostic (3.51e-1)" "unprognostic (1.41e-1)" "unprognostic (1.87e-3)" 10.6 14.6 9.0 4.5 8.6 2.8 11.4 11.1 10.5 14.7 4.2 14.1 11.1 11.8 2.6 16.7 11.9 3.8 17.0 8.2 7.5 16.2 35.6 8.6 3.8 9.4 8.1 15.1 13.2 6.6 12.2 3.3 8.6 26.3 3.8 4.6 11.6 5.5 12.0 9.1 11.7 2.8 7.2 9.9 12.3 7.4 8.4 4.5 12.6 3.5 2.4 15.0 11.8 11.5 6.8 16.8 9.8 7.9 4.0 3.4 8.2 7.2 3.9 3.9 3.9 8.3 11.2 11.9 11.4 4.5 3.3 8.1 2.2 2.5 1.4 9.0 25.7 23.0 10.4 15.6 4.2 3.5 10.8 5.1 5.5 2.5 2.5 6.4 2.7 6.6 19.1 5.9 2.9 35.7 8.9 14.2 5.3 10.1 46.6 9.9 3.3 5.8 6.1 10.1 33.3 27.3 11.0 7.8 7.1 3.3 14.3 7.1 14.6 7.5 28.7 8.4 5.3 4.2 2.8 9.8 9.9 4.3 7.3 0.1 0.3 0.3 0.0 0.1 0.1 0.2 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.3 0.2 0.2 0.0 9.0 8.6 11.1 10.5 8.2 7.5 9.4 8.1 8.6 7.2 8.4 11.5 12.2 3.2 6.9 0.3 12.9 15.9 49.6 1.9 23.3 30.4 39.6 38.6 17.9 18.6 1.9 16.5 14.6 33.4 13.0 46.3 138.9 5.8 16.8 10.3 22.1 12.3 34.2 14.9 0.1 7.7 35.1 18.5 19.4 26.0 5.7 16.3 9.7 69.8 18.6 28.6 0.1 31.9 2.0 16.1 16.1 21.4 24.2 15.2 33.8 0.0 7.5 28.0 13.4 0.0 0.1 6.7 22.1 20.3 16.3 55.6 35.4 99.1 0.4 35.8 32.9 21.1 23.0 24.4 18.8 36.9 20.9 25.2 13.1 34.5 34.6 43.3 C9 ENSG00000113600 "Complement C9" P02748 5 39284140-39424868 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 288 "liver: 1397.0" "Cell type enriched" "Detected in some" 37 "Hepatocytes: 1962.3" "Cancer enriched" "Detected in single" 244 "liver cancer: 90.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "JURKAT: 9.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002151, HPA029577" Uncertain "Secreted to blood" NA NA 69600000000 64000000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" "CAB002151: AB_563670, HPA029577: AB_10603779" "unprognostic (1.00e-1)" "unprognostic (1.57e-1)" "unprognostic (1.50e-1)" "unprognostic (2.01e-1)" "unprognostic (6.58e-2)" "unprognostic (1.30e-1)" "unprognostic (2.91e-1)" "unprognostic (5.49e-3)" "unprognostic (1.91e-2)" "unprognostic (1.29e-2)" "unprognostic (2.19e-2)" "unprognostic (9.43e-5)" "unprognostic (1.36e-1)" "unprognostic (1.80e-1)" "unprognostic (2.04e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1397.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 6.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 20.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.6 0.0 0.8 2.0 0.0 18.7 0.1 0.0 0.0 0.5 0.0 0.1 0.0 0.0 42.5 1962.3 1.2 0.0 0.1 0.2 0.0 52.6 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.4 0.1 3.7 1.7 0.0 0.0 0.3 3.0 0.0 0.0 0.1 CA2 "CA-II, CAII, Car2" ENSG00000104267 "Carbonic anhydrase 2" P00918 8 85463968-85481493 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "Disease variant, FDA approved drug targets, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 687.4;stomach 1: 1108.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1773.2;Erythroid cells: 2448.1;Gastric mucus-secreting cells: 1380.7;Muller glia cells: 1536.4;Paneth cells: 781.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 51.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 263.8;HEK 293: 1097.8;THP-1: 461.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001550, CAB010102" Enhanced NA Yes 570000000 "Cluster 38: Basophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" "CAB010102: AB_626796, HPA001550: AB_1078393" "unprognostic (6.78e-2)" "unprognostic (3.06e-2)" "unprognostic (1.05e-2)" "unprognostic (1.63e-1)" "unprognostic (2.59e-1)" "unprognostic (9.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.72e-2)" "unprognostic (1.07e-1)" "unprognostic (5.23e-2)" "unprognostic (1.57e-1)" "unprognostic (9.89e-2)" "prognostic favorable (5.57e-6)" "unprognostic (2.45e-1)" "unprognostic (2.03e-1)" "unprognostic (1.32e-1)" "unprognostic (6.49e-3)" 7.4 10.1 95.9 36.8 127.5 246.8 37.9 122.1 143.8 5.0 444.0 687.4 285.2 2.9 10.6 19.8 2.7 112.7 15.9 105.2 107.8 331.2 273.5 43.1 6.6 115.5 112.0 0.4 55.1 10.1 6.1 19.6 114.2 1.9 643.6 390.4 74.7 68.4 42.7 81.0 31.3 32.3 98.2 8.4 1108.7 21.2 115.6 5.1 15.9 62.8 4.3 2.9 5.2 145.5 3.7 2.8 12.2 0.0 0.1 0.0 31.2 0.0 0.0 0.0 0.0 15.1 0.9 0.0 9.5 0.0 0.1 263.8 37.4 13.2 0.0 0.0 1097.8 35.8 17.0 0.5 0.0 23.7 5.1 0.0 63.9 0.0 3.7 0.0 0.0 0.0 0.3 0.2 0.0 0.4 0.4 41.4 3.7 86.5 0.0 21.2 1.3 0.5 3.7 8.8 0.2 0.3 5.0 0.0 0.1 9.6 0.0 461.5 0.0 0.0 6.6 0.0 0.4 0.4 1.0 0.1 1.8 0.1 0.0 51.2 5.3 8.6 0.2 15.0 7.4 1.3 0.1 0.8 15.4 3.0 0.0 0.0 12.6 0.1 13.4 1.4 0.0 33.3 95.9 127.5 122.1 143.8 105.2 107.8 115.5 112.0 114.2 98.2 115.6 145.5 19.4 16.0 79.9 34.0 19.6 90.6 1.3 152.5 17.6 23.1 56.9 18.4 19.8 430.4 22.4 161.8 64.6 15.2 2.4 1773.2 348.3 60.1 65.9 3.3 1.3 26.7 30.5 2448.1 1.4 11.3 403.1 6.4 1380.7 8.3 15.9 0.4 4.2 135.6 35.4 13.5 22.3 116.0 10.2 11.0 216.5 232.1 3.4 51.8 74.7 6.5 6.6 1536.4 1.0 3.0 226.4 16.1 781.9 2.2 10.3 3.5 0.3 468.2 3.9 66.1 0.0 12.1 8.2 3.1 2.8 31.2 111.7 17.1 11.7 0.7 390.8 0.5 CARMIL2 "LRRC16C, RLTPR" ENSG00000159753 "Capping protein regulator and myosin 1 linker 2" Q6F5E8 16 67644988-67657569 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.4;intestine: 13.4;lymphoid tissue: 21.6" "Group enriched" "Detected in some" 4 "B-cells: 3.6;dendritic cells: 3.7;T-cells: 3.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 64.2;JURKAT: 47.3;MOLT-4: 64.6;REH: 105.6;RPMI-8226: 58.4;U-698: 107.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041402 Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "HPA041402: AB_10795591" "unprognostic (1.63e-2)" "unprognostic (1.17e-2)" "unprognostic (1.35e-2)" "unprognostic (6.37e-2)" "unprognostic (5.47e-3)" "unprognostic (4.27e-4)" "unprognostic (1.38e-2)" "unprognostic (1.44e-1)" "unprognostic (3.85e-2)" "unprognostic (1.52e-1)" "unprognostic (7.90e-5)" "unprognostic (4.07e-2)" "unprognostic (5.14e-10)" "unprognostic (2.25e-1)" "unprognostic (1.89e-1)" "unprognostic (1.85e-1)" "unprognostic (6.57e-2)" 0.9 0.5 5.9 12.5 6.3 5.9 0.5 4.5 11.4 0.4 2.4 2.0 1.8 0.3 0.1 0.9 0.5 1.2 0.3 9.8 5.1 0.9 0.8 1.7 21.6 5.6 4.0 0.2 0.4 0.1 4.5 0.2 5.4 0.8 0.7 0.3 1.4 0.1 0.0 0.4 13.4 0.2 3.4 19.9 1.9 0.9 4.9 20.9 1.2 0.0 10.9 1.5 0.7 6.8 0.2 0.1 0.1 0.3 0.0 0.1 18.1 0.6 0.0 0.5 0.0 9.6 0.6 64.2 1.1 0.0 0.1 0.1 6.0 0.0 0.0 14.3 7.5 3.8 0.3 1.2 0.5 7.1 0.6 0.1 0.0 0.0 0.1 0.1 0.0 47.3 0.9 1.0 0.0 1.1 64.6 32.2 10.7 0.3 0.3 105.6 0.1 58.4 0.0 0.0 15.9 1.7 0.1 0.2 0.5 1.5 0.4 1.9 0.2 0.9 2.0 0.1 0.4 17.6 33.4 107.2 0.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.2 0.7 0.1 0.0 0.4 0.2 0.1 0.0 0.4 0.0 0.3 0.7 0.1 5.9 6.3 4.5 11.4 9.8 5.1 5.6 4.0 5.4 3.4 4.9 6.8 0.4 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.9 0.2 0.0 0.0 CARMIL3 "BC008134, C14orf121, crml-1, LRRC16B" ENSG00000186648 "Capping protein regulator and myosin 1 linker 3" Q8ND23 14 24052009-24069729 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 3.6;pituitary gland: 8.1;skin 1: 3.9;testis: 2.2" "Cell type enhanced" "Detected in single" "Collecting duct cells: 1.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 5.5;HMC-1: 3.7;Karpas-707: 3.3;SCLC-21H: 5.4;SH-SY5Y: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030596 Uncertain NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "HPA030596: AB_10603012" "unprognostic (2.67e-2)" "unprognostic (2.07e-3)" "unprognostic (1.50e-1)" "unprognostic (3.09e-2)" "unprognostic (6.17e-2)" "unprognostic (1.29e-4)" "unprognostic (6.13e-2)" "unprognostic (8.92e-4)" "unprognostic (4.02e-1)" "unprognostic (7.08e-2)" "unprognostic (1.39e-4)" "unprognostic (4.49e-2)" "unprognostic (1.17e-1)" "unprognostic (7.01e-2)" "unprognostic (1.25e-2)" "unprognostic (4.19e-1)" "unprognostic (2.16e-1)" 0.1 0.3 2.0 0.3 1.5 0.2 0.3 3.6 2.1 0.3 0.0 0.5 0.5 0.2 0.0 0.6 0.1 0.3 0.1 1.9 1.3 0.7 0.2 0.3 0.3 2.0 1.4 0.1 0.7 0.0 8.1 0.0 2.0 0.3 0.1 1.0 0.6 0.0 0.0 3.9 0.7 0.0 0.5 0.5 0.3 2.2 1.9 0.1 0.5 0.0 0.4 0.1 0.5 1.8 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.9 0.0 0.1 0.1 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.3 0.0 0.2 0.8 0.0 0.3 0.1 0.1 0.4 0.0 0.0 0.0 0.0 5.4 2.6 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.5 3.6 2.1 1.9 1.3 2.0 1.4 2.0 0.5 1.9 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 CBR1 "CBR, SDR21C1" ENSG00000159228 "Carbonyl reductase 1" P16152 21 36069941-36073166 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 583.9" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 524.2;Distal tubular cells: 757.2;Proximal enterocytes: 1270.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA018433, CAB034291" Enhanced Approved Nucleoplasm,Cytosol NA NA 12000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 45: Intestine - Brush border" "Cluster 16: U-266 - Nucleosome" "Cluster 45: Enterocytes - Digestion" Nucleoplasm Cytosol "CAB034291: AB_2070856, HPA018433: AB_1846109" "prognostic favorable (2.18e-4)" "unprognostic (9.78e-2)" "unprognostic (3.25e-2)" "unprognostic (2.14e-1)" "unprognostic (6.47e-3)" "unprognostic (1.69e-1)" "unprognostic (1.19e-1)" "unprognostic (6.37e-2)" "unprognostic (4.56e-2)" "unprognostic (1.28e-1)" "unprognostic (7.20e-2)" "unprognostic (4.00e-1)" "prognostic favorable (4.75e-4)" "unprognostic (2.37e-1)" "unprognostic (2.47e-1)" "unprognostic (6.13e-3)" "unprognostic (2.47e-2)" 32.4 95.3 150.0 25.6 200.0 10.1 29.5 186.1 174.1 52.7 207.0 68.6 583.9 41.3 50.5 189.5 34.6 47.1 29.5 154.6 166.7 125.6 252.8 41.1 28.3 173.1 175.1 28.8 36.1 38.6 35.3 27.6 175.6 48.7 50.9 10.2 101.8 42.2 33.6 111.8 345.9 34.4 166.2 39.9 133.5 18.1 180.3 22.7 46.4 23.3 36.7 51.0 85.3 266.6 114.4 180.4 22.6 55.9 115.0 115.3 1.2 123.6 97.0 72.4 86.4 68.9 67.8 28.2 78.7 128.1 137.3 84.6 46.3 132.3 55.7 133.8 95.3 82.5 105.1 48.1 65.7 49.1 77.5 56.1 165.6 70.7 30.8 83.0 78.4 0.0 0.0 21.3 67.6 121.2 24.7 50.7 0.4 0.0 123.3 0.4 0.4 80.5 195.7 60.9 60.5 52.1 121.3 186.3 157.3 17.6 86.1 69.4 71.1 78.8 30.8 202.9 96.1 131.8 268.9 0.7 144.0 48.6 115.6 7.1 134.0 68.6 64.4 198.5 54.6 67.2 79.7 60.8 109.6 61.2 102.6 75.4 9.2 77.3 156.9 39.6 89.0 162.1 150.0 200.0 186.1 174.1 154.6 166.7 173.1 175.1 175.6 166.2 180.3 266.6 26.4 121.8 69.3 17.9 22.5 128.2 63.1 295.2 524.2 11.6 27.7 98.8 20.9 77.2 117.1 95.6 2.1 116.6 15.7 91.2 757.2 93.7 8.9 31.7 45.5 23.1 38.6 32.0 6.5 70.0 80.4 65.7 127.4 45.1 34.9 30.8 41.7 277.2 85.1 3.3 6.8 94.4 396.7 66.6 27.5 4.3 122.7 49.5 90.7 4.7 79.2 69.8 23.7 16.6 128.2 91.8 146.6 132.4 41.3 66.4 1270.3 326.0 121.2 8.3 26.3 51.3 90.7 5.8 17.4 403.5 123.6 89.2 30.7 55.6 145.8 55.0 CCDC106 HSU79303 ENSG00000173581 "Coiled-coil domain containing 106" Q9BWC9 19 55641062-55653161 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 69.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 9.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEK 293: 82.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041925, HPA043219" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Cytosol "HPA041925: AB_2677750, HPA043219: AB_2678368" "unprognostic (5.74e-3)" "unprognostic (1.34e-1)" "unprognostic (1.71e-1)" "unprognostic (5.16e-2)" "unprognostic (9.19e-2)" "unprognostic (2.82e-1)" "unprognostic (8.11e-2)" "unprognostic (1.21e-2)" "unprognostic (4.88e-2)" "unprognostic (8.74e-2)" "prognostic favorable (2.23e-6)" "unprognostic (2.28e-1)" "prognostic favorable (7.54e-11)" "unprognostic (5.03e-2)" "unprognostic (7.88e-2)" "unprognostic (3.26e-1)" "unprognostic (8.69e-2)" 12.0 21.7 27.8 5.1 32.7 2.6 11.9 20.4 37.6 11.4 17.7 18.7 4.1 13.4 6.4 8.0 13.3 6.5 21.9 33.0 22.4 29.1 24.3 9.4 10.3 21.8 23.1 12.7 9.8 13.6 27.3 5.1 21.1 15.2 2.7 6.5 11.1 11.2 24.5 9.3 13.7 7.1 18.4 18.2 13.7 20.8 23.5 4.7 16.7 20.2 9.0 12.8 8.3 24.7 8.7 33.6 14.4 25.3 10.1 9.6 2.0 7.4 12.9 25.0 21.0 7.3 13.2 25.6 5.6 13.8 0.7 7.3 24.6 16.0 7.1 1.3 82.2 26.7 23.4 13.3 30.1 1.8 14.3 15.6 1.9 5.9 1.4 17.4 8.0 16.0 20.1 15.7 12.5 2.3 16.3 10.8 6.9 0.8 18.3 25.5 7.3 17.7 25.9 0.8 15.8 29.4 5.9 41.3 14.7 8.5 17.9 17.3 9.0 7.7 7.9 0.7 5.5 9.3 3.5 33.0 20.7 8.4 0.6 0.0 2.3 0.0 0.4 1.5 1.4 7.2 0.4 0.6 2.9 9.6 3.1 1.9 0.0 0.8 0.1 8.9 0.3 1.7 27.8 32.7 20.4 37.6 33.0 22.4 21.8 23.1 21.1 18.4 23.5 24.7 12.0 0.0 1.3 8.8 18.1 2.5 6.0 14.0 12.0 22.3 16.0 17.1 23.8 11.5 6.5 20.2 4.2 13.5 6.8 4.6 41.1 19.6 4.0 3.9 7.2 10.8 4.9 4.2 6.4 7.2 15.0 9.7 11.7 3.3 8.9 10.5 10.0 17.5 17.5 37.0 6.4 8.7 8.2 9.4 6.4 2.7 14.0 7.9 3.6 3.7 11.7 34.1 3.1 4.5 3.6 8.7 8.0 18.8 7.0 6.0 10.6 69.4 3.2 9.7 13.1 9.3 9.0 4.7 30.2 10.3 3.7 8.8 3.9 18.9 6.0 5.7 CCDC146 "KIAA1505, MBO2" ENSG00000135205 "Coiled-coil domain containing 146" Q8IYE0 7 77122434-77329533 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 34.0" "Cell type enhanced" "Detected in many" "Early spermatids: 308.3;Endometrial ciliated cells: 460.8;Oligodendrocyte precursor cells: 151.3;Respiratory ciliated cells: 417.9;Spermatocytes: 149.4" "Group enriched" "Detected in all" 4 "endometrial cancer: 8.8;ovarian cancer: 13.6;renal cancer: 15.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 14.3;neutrophil: 15.4" "Group enriched" "Detected in many" 4 "granulocytes: 15.4;NK-cells: 5.3;T-cells: 4.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA020082, HPA020105" Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 24: NB-4 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "HPA020082: AB_1852410, HPA020105: AB_2072056" "unprognostic (3.07e-3)" "unprognostic (9.94e-3)" "unprognostic (1.56e-1)" "unprognostic (2.54e-3)" "unprognostic (1.85e-1)" "prognostic favorable (7.37e-4)" "unprognostic (1.95e-3)" "unprognostic (8.02e-3)" "unprognostic (4.05e-4)" "unprognostic (1.73e-1)" "unprognostic (4.63e-1)" "unprognostic (4.09e-2)" "unprognostic (7.38e-2)" "unprognostic (2.28e-1)" "unprognostic (2.29e-1)" "unprognostic (2.70e-3)" "unprognostic (5.58e-3)" 2.2 1.1 4.0 2.5 3.7 1.7 2.4 2.0 2.5 4.5 18.3 3.8 2.4 4.6 2.5 3.6 34.0 3.1 1.8 2.7 4.4 4.2 1.8 5.2 3.0 11.5 11.4 3.3 2.5 3.9 3.8 1.9 7.4 3.7 2.7 14.5 4.1 2.3 1.1 9.4 2.8 3.0 7.8 3.7 3.3 21.5 3.9 3.1 7.7 1.6 2.7 3.1 3.9 6.3 0.6 0.9 2.7 1.4 1.7 1.7 0.3 0.7 0.6 0.7 1.1 0.0 4.6 1.4 0.1 0.2 2.6 0.9 0.4 0.8 1.1 1.9 0.3 1.8 1.5 0.8 0.5 1.8 1.3 0.8 1.3 1.2 0.2 2.2 0.6 1.4 0.0 1.4 0.1 0.2 1.5 2.9 0.3 0.6 0.6 4.0 0.4 0.2 2.8 0.5 2.0 1.3 1.0 0.9 0.6 0.8 0.8 0.6 0.9 1.0 0.4 1.4 0.4 2.7 4.5 1.2 2.3 2.7 2.3 0.9 0.6 14.3 4.4 0.9 3.0 1.2 1.9 3.1 0.8 0.2 1.2 2.0 15.4 5.3 0.4 2.0 1.6 0.8 4.0 3.7 2.0 2.5 2.7 4.4 11.5 11.4 7.4 7.8 3.9 6.3 6.9 3.2 9.7 34.0 3.6 7.1 2.6 16.9 6.2 8.6 2.7 4.6 32.0 2.8 56.9 5.5 62.6 1.2 9.3 2.8 21.5 3.2 308.3 460.8 11.1 4.8 1.8 0.4 49.0 1.6 0.7 15.4 6.1 106.0 6.3 6.1 23.6 0.8 1.6 5.0 48.8 1.4 24.4 3.5 7.1 52.4 12.2 4.5 5.4 50.6 2.0 12.1 20.6 151.3 62.8 1.7 5.2 6.4 3.7 5.8 2.9 30.1 417.9 55.1 6.6 15.6 11.6 149.4 10.8 5.5 3.4 2.5 8.6 7.2 4.0 5.4 CCDC73 NY-SAR-79 ENSG00000186714 "Coiled-coil domain containing 73" Q6ZRK6 11 32602246-32794658 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 3.7" "Group enriched" "Detected in some" 16 "Spermatocytes: 160.3;Spermatogonia: 84.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "MOLT-4: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038668, HPA038669" Uncertain NA NA "Cluster 24: B-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA038668: AB_10673292, HPA038669: AB_2676142" "unprognostic (9.41e-3)" "unprognostic (2.46e-2)" "unprognostic (2.36e-1)" "unprognostic (8.65e-2)" "unprognostic (5.79e-2)" "unprognostic (1.14e-2)" "unprognostic (1.89e-1)" "unprognostic (1.73e-4)" "unprognostic (1.74e-1)" "unprognostic (2.02e-2)" "unprognostic (2.10e-2)" "unprognostic (3.27e-2)" "unprognostic (1.62e-5)" "unprognostic (3.87e-1)" "unprognostic (1.02e-1)" "unprognostic (1.68e-1)" "unprognostic (1.20e-3)" 0.0 0.2 0.1 0.1 0.0 0.3 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.4 0.0 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.0 3.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 1.8 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.4 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 3.2 0.6 2.3 0.1 0.0 0.3 0.2 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.2 0.0 1.9 0.0 4.8 1.8 0.5 0.6 0.0 0.0 4.5 0.2 0.1 0.2 0.0 0.6 0.0 0.2 0.0 1.1 0.2 0.0 3.9 0.1 0.0 0.0 0.0 4.3 0.6 0.1 0.0 7.5 0.1 0.0 0.0 3.5 1.7 0.3 1.2 0.7 0.3 0.3 0.0 0.9 1.0 0.6 6.6 0.0 0.2 160.3 84.2 0.0 0.0 0.1 0.2 4.3 0.0 0.5 CCL15 "HCC-2, HMRP-2B, Lkn-1, MIP-1d, MIP-5, NCC-3, SCYA15, SCYL3" ENSG00000275718 "C-C motif chemokine ligand 15" Q16663 17 35996440-36001553 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Cytokine, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 83.0;liver: 31.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 262.6;Intestinal goblet cells: 208.3;Paneth cells: 380.6;Proximal enterocytes: 461.4;Undifferentiated cells: 138.2" "Cancer enhanced" "Detected in many" "liver cancer: 11.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "Hep G2: 35.4;OE19: 28.7" HPA058608 Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 3270000 11000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" Vesicles "HPA058608: AB_2683776" "unprognostic (1.26e-1)" "unprognostic (1.23e-1)" "unprognostic (1.31e-2)" "unprognostic (1.40e-1)" "unprognostic (8.88e-2)" "unprognostic (1.50e-1)" "unprognostic (1.63e-1)" "unprognostic (2.45e-1)" "unprognostic (2.41e-2)" "unprognostic (1.96e-2)" "unprognostic (9.94e-2)" "unprognostic (1.15e-1)" "unprognostic (1.07e-2)" "prognostic favorable (3.02e-4)" 0.2 0.4 0.1 7.8 0.1 0.1 0.4 0.1 0.3 0.3 0.0 59.7 37.6 0.1 0.0 0.2 9.6 9.2 0.0 0.1 0.1 10.0 31.6 2.1 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 83.0 0.0 0.1 0.1 0.0 0.1 62.0 1.4 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.3 4.9 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 35.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.1 0.0 28.7 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.3 0.5 0.0 0.5 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.1 0.1 7.2 5.0 0.0 0.0 0.0 0.0 262.6 0.0 0.0 0.0 12.2 0.1 0.7 71.8 0.0 0.0 0.7 0.0 0.0 0.0 0.1 8.9 0.0 2.5 40.2 0.1 0.0 0.0 208.3 2.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 380.6 0.0 0.0 0.0 461.4 61.3 76.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 138.2 0.2 CCM2L "C20orf160, dJ310O13.5" ENSG00000101331 "CCM2 like scaffold protein" Q9NUG4 20 32010438-32032180 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 141.6" "Cell type enriched" "Detected in some" 5 "Theca cells: 248.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 8.2;HUVEC TERT2: 9.0;NTERA-2: 4.6;RH-30: 3.2;SCLC-21H: 7.7;TIME: 4.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008434, HPA071063" Uncertain Supported Nucleoplasm NA NA "Cluster 64: Macrophages - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA008434: AB_1845671, HPA071063: AB_2686339" "unprognostic (1.71e-1)" "unprognostic (4.64e-2)" "unprognostic (2.43e-3)" "unprognostic (5.84e-3)" "unprognostic (1.91e-1)" "unprognostic (3.09e-3)" "unprognostic (1.27e-3)" "unprognostic (2.37e-1)" "unprognostic (2.04e-1)" "unprognostic (4.34e-2)" "unprognostic (1.00e-3)" "unprognostic (7.84e-2)" "unprognostic (4.66e-3)" "unprognostic (2.19e-2)" "unprognostic (1.57e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" 15.9 5.4 7.2 1.6 7.3 0.0 15.0 9.5 6.8 8.7 4.2 4.6 1.3 8.9 0.6 3.7 7.7 2.5 23.2 6.1 5.8 13.3 2.2 11.8 1.5 6.8 6.4 3.6 2.6 1.4 4.1 7.8 7.0 5.8 1.1 0.4 3.4 1.8 4.8 3.9 5.4 3.3 6.1 141.6 4.2 1.6 7.3 0.8 10.2 4.8 0.9 6.4 6.3 5.2 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 9.0 0.9 0.0 0.0 0.0 2.4 0.0 0.0 4.6 0.1 0.0 0.6 3.2 0.1 0.0 0.0 7.7 0.9 0.2 0.0 0.0 1.1 2.5 0.0 4.8 0.0 1.3 0.0 0.0 0.1 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 7.3 9.5 6.8 6.1 5.8 6.8 6.4 7.0 6.1 7.3 5.2 45.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.6 0.5 0.6 4.6 2.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.2 32.1 0.0 0.0 2.9 0.2 0.0 1.0 0.0 0.2 0.0 4.3 24.3 0.0 0.0 3.3 2.4 0.0 0.0 0.3 0.3 0.4 0.0 0.2 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.6 1.8 0.3 0.6 0.1 0.3 0.0 0.1 248.7 0.0 0.1 CD177 "HNA2A, NB1, PRV1" ENSG00000204936 "CD177 molecule" 19 43353686-43363172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 285.9;intestine: 164.6" "Group enriched" "Detected in some" 5 "Distal enterocytes: 632.4;Paneth cells: 314.8" "Cancer enhanced" "Detected in many" "prostate cancer: 27.6" "Group enriched" "Detected in many" 4 "cerebellum: 3.6;cerebral cortex: 7.7;pons: 2.3" "Immune cell enriched" "Detected in some" 7 "neutrophil: 8.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 8.7" "Cell line enriched" "Detected in some" 26 "RPMI-8226: 98.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041820, HPA046601, HPA077640" Enhanced "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA041820: AB_2677691, HPA046601: AB_2679716, HPA077640: " "unprognostic (4.32e-2)" "prognostic favorable (3.66e-4)" "unprognostic (1.04e-2)" "unprognostic (2.04e-3)" "unprognostic (1.61e-1)" "unprognostic (3.89e-2)" "unprognostic (7.10e-2)" "unprognostic (2.94e-1)" "unprognostic (2.05e-1)" "unprognostic (1.45e-1)" "unprognostic (8.38e-2)" "unprognostic (1.90e-2)" "unprognostic (2.45e-1)" "unprognostic (2.70e-1)" "unprognostic (1.16e-1)" "unprognostic (5.01e-2)" "unprognostic (1.24e-1)" 4.8 0.4 0.1 7.2 0.3 285.9 1.3 3.6 7.7 6.0 3.7 155.2 0.3 0.4 0.2 2.2 2.3 0.2 2.2 0.3 0.1 1.9 2.6 20.6 0.2 0.3 1.0 0.3 1.1 0.0 2.9 1.6 2.3 64.8 164.6 0.1 1.8 0.2 0.7 0.4 0.7 3.0 0.3 64.4 1.4 0.2 0.4 1.4 0.7 0.8 10.4 2.1 5.4 0.5 2.1 0.0 0.0 0.0 0.0 0.0 0.3 1.0 1.3 0.6 0.6 0.0 0.0 0.1 2.4 0.6 1.7 0.2 0.1 0.0 1.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 1.2 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.4 1.2 0.0 0.2 0.0 0.0 98.0 1.4 0.3 0.7 0.0 0.5 0.1 0.0 0.2 0.0 0.0 0.0 1.0 0.3 2.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 1.2 0.0 0.7 0.0 0.1 0.3 3.6 7.7 0.3 0.1 0.3 1.0 2.3 0.3 0.4 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 3.1 0.0 0.0 0.0 0.0 632.4 0.0 0.5 0.4 0.2 0.1 0.0 8.4 3.6 0.0 0.2 0.0 0.2 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.2 87.2 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 314.8 0.0 0.1 29.2 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 28.0 0.2 CD2 SRBC ENSG00000116824 "CD2 molecule" P06729 1 116754430-116769229 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 249.8" "Group enriched" "Detected in many" 6 "dendritic cells: 158.3;NK-cells: 178.2;T-cells: 476.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 6 "gdT-cell: 421.8;MAIT T-cell: 403.1;memory CD4 T-cell: 610.2;memory CD8 T-cell: 714.1;naive CD4 T-cell: 316.3;naive CD8 T-cell: 486.2;NK-cell: 1108.0;T-reg: 655.2" "Group enriched" "Detected in all" 10 "NK-cells: 1108.0;T-cells: 714.1" "Group enriched" "Detected in some" 25 "HDLM-2: 224.1;JURKAT: 145.8;MOLT-4: 166.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002430, HPA003883" Enhanced Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "CAB002430: AB_442057, HPA003883: AB_1846263" "prognostic favorable (4.36e-4)" "prognostic favorable (1.47e-4)" "unprognostic (3.34e-3)" "prognostic favorable (1.69e-5)" "unprognostic (1.52e-1)" "prognostic favorable (7.46e-5)" "unprognostic (9.32e-3)" "unprognostic (1.61e-2)" "prognostic favorable (3.97e-5)" "prognostic favorable (7.72e-4)" "unprognostic (4.18e-2)" "unprognostic (3.31e-1)" "prognostic unfavorable (4.82e-6)" "unprognostic (6.16e-2)" "unprognostic (6.61e-2)" "unprognostic (2.73e-2)" "unprognostic (7.63e-3)" 4.6 4.6 0.6 51.3 0.7 11.4 7.6 0.6 1.0 5.8 0.8 13.9 17.2 3.7 2.8 8.4 4.2 16.8 2.6 0.5 0.8 2.5 7.8 21.0 119.6 1.7 0.7 2.8 2.9 0.9 0.7 1.0 1.1 5.2 16.0 0.0 8.6 2.3 1.4 3.5 28.4 4.4 1.0 44.1 24.1 1.8 1.0 249.8 3.8 1.7 79.1 20.8 3.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 224.1 0.0 0.4 0.0 0.0 0.0 0.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 145.8 0.1 0.5 0.0 0.0 166.9 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.8 0.4 0.0 11.3 5.2 1.6 421.8 3.7 403.1 3.8 610.2 714.1 95.4 2.5 316.3 486.2 14.1 1108.0 2.8 21.0 655.2 565.1 0.6 0.7 0.6 1.0 0.5 0.8 1.7 0.7 1.1 1.0 1.0 1.1 5.0 3.2 17.5 0.0 12.3 5.0 0.4 0.0 2.2 0.0 4.0 4.7 2.1 0.0 2.5 3.7 0.0 0.1 158.3 0.2 0.0 0.5 23.5 1.1 1.0 2.9 3.0 24.0 0.0 0.0 0.0 2.5 10.7 0.9 5.1 0.0 8.2 1.5 0.6 0.0 0.0 0.0 0.0 10.9 16.6 7.8 0.6 19.1 1.8 1.0 15.5 0.0 178.2 0.0 0.0 0.0 0.0 0.4 42.3 0.1 0.0 1.7 0.0 0.0 0.0 2.9 4.1 0.3 0.2 0.4 3.7 0.0 476.8 0.0 0.5 0.2 CD302 "BIMLEC, CLEC13A, DCL-1, KIAA0022" ENSG00000241399 "CD302 molecule" Q8IX05 2 159768628-159798255 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 193.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 352.2;Kupffer cells: 382.4;Macrophages: 194.3;monocytes: 166.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 215 "dendritic cells: 24.4;granulocytes: 32.2;monocytes: 33.0" "Cell line enriched" "Detected in many" 5 "ASC diff: 246.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 110000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (2.52e-1)" "unprognostic (5.44e-2)" "unprognostic (1.19e-2)" "unprognostic (1.50e-1)" "unprognostic (2.03e-1)" "unprognostic (6.88e-2)" "unprognostic (1.68e-2)" "unprognostic (9.12e-3)" "unprognostic (5.29e-3)" "unprognostic (2.37e-2)" "unprognostic (4.38e-2)" "unprognostic (2.14e-1)" "unprognostic (4.67e-3)" "unprognostic (1.75e-2)" "unprognostic (6.61e-2)" "unprognostic (7.45e-2)" "unprognostic (3.61e-3)" 49.4 25.5 6.5 15.5 6.6 30.6 31.0 7.1 9.2 34.6 10.6 16.8 24.1 21.8 14.2 11.7 15.0 30.7 13.3 6.1 7.5 16.9 193.8 50.0 11.7 8.8 7.2 41.9 17.6 10.9 3.2 19.4 8.5 21.3 20.7 2.1 12.0 20.4 2.9 6.2 28.1 22.5 7.5 31.3 15.7 9.0 6.6 9.7 31.1 17.3 9.9 24.6 13.3 8.5 0.1 1.4 1.2 0.0 246.9 51.5 0.0 5.3 25.9 7.4 10.9 1.6 2.2 0.4 2.0 13.5 7.8 0.0 5.5 3.0 10.1 1.6 8.6 7.0 1.3 3.6 12.3 18.6 6.0 41.2 1.4 8.0 0.0 6.0 18.9 0.0 0.6 5.8 9.5 0.6 0.0 13.1 2.4 0.0 6.7 0.0 1.8 0.2 1.6 0.2 2.7 2.9 1.8 5.9 5.7 3.8 4.8 18.3 4.1 13.7 0.0 0.2 4.1 0.5 0.0 0.0 9.9 1.5 3.1 13.5 33.0 32.2 0.0 24.1 0.0 0.1 0.0 0.0 24.4 0.1 0.0 0.0 29.2 0.1 26.1 6.8 0.0 12.5 6.5 6.6 7.1 9.2 6.1 7.5 8.8 7.2 8.5 7.5 6.6 8.5 28.0 44.8 111.9 0.0 5.0 6.6 15.9 2.4 16.5 3.3 20.2 15.2 3.9 31.5 26.5 3.7 0.0 2.5 19.3 3.7 0.0 4.0 31.7 3.0 38.7 25.3 9.6 21.0 0.0 3.5 10.5 80.5 20.4 3.0 30.9 26.7 65.7 352.2 42.7 3.3 0.0 25.2 0.0 382.4 97.3 16.4 122.7 194.3 19.6 0.0 166.6 2.1 2.1 0.0 0.0 2.3 12.2 93.6 3.5 13.9 19.6 4.1 17.1 2.4 65.7 24.8 30.7 27.9 11.6 3.6 4.4 2.7 6.5 8.6 22.7 10.4 CD3D T3D ENSG00000167286 "CD3d molecule" P04234 11 118339075-118342705 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 30 "lymphoid tissue: 906.7" "Group enriched" "Detected in many" 14 "dendritic cells: 231.0;T-cells: 665.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 52 "gdT-cell: 1462.4;MAIT T-cell: 990.0;memory CD4 T-cell: 1206.1;memory CD8 T-cell: 1368.7;naive CD4 T-cell: 1091.4;naive CD8 T-cell: 1338.9;T-reg: 1660.4" "Lineage enriched" "Detected in all" 66 "T-cells: 1660.4" "Group enriched" "Detected in some" 4 "JURKAT: 621.5;MOLT-4: 1299.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013055, HPA071778" Enhanced Uncertain "Endoplasmic reticulum" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum" "CAB013055: , HPA071778: " "prognostic favorable (3.00e-4)" "prognostic favorable (8.46e-5)" "unprognostic (1.05e-2)" "prognostic favorable (1.73e-7)" "unprognostic (6.00e-2)" "prognostic favorable (1.70e-4)" "unprognostic (3.82e-1)" "unprognostic (2.40e-2)" "unprognostic (2.24e-3)" "unprognostic (1.01e-2)" "unprognostic (5.69e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (3.07e-5)" "unprognostic (9.00e-2)" "unprognostic (2.02e-1)" "unprognostic (3.66e-2)" "prognostic favorable (6.16e-4)" 4.1 3.8 0.3 77.5 0.4 28.6 9.9 0.4 1.4 5.2 0.7 18.8 21.7 3.6 5.7 7.6 4.5 15.7 3.7 0.3 0.6 2.3 7.9 20.6 222.7 1.1 0.4 3.2 1.3 0.9 0.8 1.2 0.6 5.9 22.4 0.3 8.3 3.1 2.5 4.0 30.1 3.9 0.7 60.9 23.8 2.4 0.5 906.7 3.8 1.4 166.9 26.7 3.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 621.5 49.8 0.0 0.0 0.0 1299.8 237.2 1.2 0.0 0.0 0.7 0.1 0.5 0.0 0.0 0.4 0.0 0.0 1.9 0.0 0.2 0.8 0.0 0.5 0.0 1.5 1.1 0.0 0.9 1.1 0.4 0.0 0.1 0.0 10.1 5.3 4.6 1462.4 3.3 990.0 9.6 1206.1 1368.7 5.0 3.7 1091.4 1338.9 25.1 4.2 5.3 6.0 1660.4 1138.7 0.3 0.4 0.4 1.4 0.3 0.6 1.1 0.4 0.6 0.7 0.5 0.8 5.9 6.4 29.6 0.0 18.6 15.3 0.3 0.0 1.8 0.0 5.4 6.7 2.8 7.2 2.6 3.7 0.0 0.4 231.0 0.9 0.0 1.3 0.4 0.8 0.8 5.0 1.2 16.8 0.0 0.0 0.0 8.3 21.4 0.9 12.6 0.0 7.9 3.1 0.6 0.0 0.0 0.2 0.0 14.9 28.4 0.7 0.0 14.2 12.4 1.0 25.0 0.0 32.0 0.0 0.0 0.1 0.2 0.0 21.0 0.3 0.0 3.4 1.5 0.0 0.0 2.5 5.8 0.1 1.2 1.4 11.8 0.3 665.7 0.0 1.1 0.2 CD3E ENSG00000198851 "CD3e molecule" P07766 11 118304730-118316175 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "lymphoid tissue: 640.4" "Group enriched" "Detected in many" 7 "dendritic cells: 213.6;NK-cells: 154.5;T-cells: 601.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 26 "gdT-cell: 490.6;MAIT T-cell: 420.8;memory CD4 T-cell: 414.4;memory CD8 T-cell: 463.5;naive CD4 T-cell: 491.7;naive CD8 T-cell: 501.3;NK-cell: 202.2;T-reg: 426.3" "Group enriched" "Detected in all" 21 "NK-cells: 202.2;T-cells: 501.3" "Group enriched" "Detected in some" 67 "JURKAT: 544.9;MOLT-4: 764.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000010, HPA040957, HPA043955, CAB072863, CAB072864" Enhanced Supported "Endoplasmic reticulum,Golgi apparatus,Plasma membrane" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Endoplasmic reticulum, Plasma membrane" "Golgi apparatus" "CAB000010: AB_2631163, CAB072863: AB_2665707, CAB072864: AB_2665708, HPA040957: AB_2677222, HPA043955: AB_2678747" "prognostic favorable (1.72e-4)" "prognostic favorable (1.62e-4)" "unprognostic (1.51e-2)" "prognostic favorable (2.30e-6)" "unprognostic (4.31e-2)" "prognostic favorable (1.32e-4)" "unprognostic (3.60e-3)" "unprognostic (3.85e-2)" "prognostic favorable (1.18e-4)" "unprognostic (6.11e-3)" "unprognostic (1.59e-1)" "unprognostic (3.59e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (5.46e-2)" "unprognostic (9.28e-2)" "unprognostic (3.13e-2)" "unprognostic (1.12e-2)" 6.4 5.6 0.9 85.8 1.1 36.7 6.7 0.9 1.2 7.1 1.3 15.3 22.0 5.8 4.6 9.5 5.4 20.1 3.8 0.7 1.0 3.5 9.7 23.0 209.6 1.8 0.9 3.8 2.2 0.7 1.0 1.6 1.4 6.6 19.3 0.0 11.6 3.0 1.9 5.4 36.4 5.1 1.2 78.9 24.4 1.7 1.3 640.4 5.3 1.6 147.0 24.8 4.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 544.9 0.9 2.0 0.0 0.0 764.9 0.6 0.3 0.0 0.0 0.2 0.1 1.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.2 0.0 1.6 8.0 9.8 0.0 0.6 0.0 16.4 1.8 2.4 490.6 1.3 420.8 1.6 414.4 463.5 1.5 2.1 491.7 501.3 12.2 202.2 2.0 8.6 426.3 333.0 0.9 1.1 0.9 1.2 0.7 1.0 1.8 0.9 1.4 1.2 1.3 1.6 4.9 0.0 8.6 0.0 12.9 5.2 0.3 0.0 0.0 0.0 3.8 4.8 0.3 0.0 0.6 1.8 0.0 0.2 213.6 0.4 0.0 0.2 7.0 0.5 0.9 2.5 0.0 6.9 0.1 0.0 0.0 5.3 24.5 0.9 7.6 0.0 8.9 2.4 0.3 0.0 0.1 0.0 0.0 7.6 8.3 0.2 0.0 12.6 12.4 1.0 8.4 0.0 154.5 0.0 0.1 0.0 1.1 0.0 41.4 0.1 0.2 2.1 0.0 0.0 0.0 1.3 2.7 0.0 0.0 1.6 5.4 0.3 601.4 0.0 0.6 0.3 CD3G ENSG00000160654 "CD3g molecule" P09693 11 118344344-118355161 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 94.7" "Group enriched" "Detected in many" 11 "dendritic cells: 139.6;T-cells: 294.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 21 "gdT-cell: 229.0;MAIT T-cell: 135.6;memory CD4 T-cell: 187.3;memory CD8 T-cell: 197.3;naive CD4 T-cell: 192.6;naive CD8 T-cell: 241.7;T-reg: 200.0" "Lineage enriched" "Detected in many" 26 "T-cells: 241.7" "Group enriched" "Detected in some" 52 "JURKAT: 70.9;MOLT-4: 193.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017520, HPA038494" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "CAB017520: AB_831094, HPA038494: AB_2676044" "prognostic favorable (6.33e-4)" "prognostic favorable (2.61e-4)" "unprognostic (4.58e-3)" "unprognostic (3.12e-5)" "unprognostic (6.30e-2)" "prognostic favorable (3.00e-4)" "unprognostic (1.98e-2)" "unprognostic (1.54e-2)" "unprognostic (8.25e-3)" "unprognostic (1.08e-3)" "unprognostic (1.54e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (9.33e-5)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (4.13e-2)" "unprognostic (2.10e-3)" 0.7 0.8 0.6 10.5 0.8 1.3 1.0 1.1 0.8 0.7 1.1 2.3 3.3 0.5 0.6 1.4 0.9 2.5 0.5 0.5 0.4 0.6 1.6 2.8 27.9 0.9 0.6 0.4 0.5 0.2 0.0 0.3 0.8 0.9 2.7 0.4 1.6 0.3 10.5 0.9 4.6 0.6 0.3 11.5 4.1 0.4 0.8 94.7 0.6 0.3 20.4 3.0 0.4 1.9 0.2 0.2 0.1 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.2 0.7 0.2 0.0 0.3 0.2 0.0 0.0 0.0 0.6 0.6 0.0 0.4 0.2 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 70.9 2.5 0.3 0.0 0.6 193.8 1.3 0.2 0.0 0.1 0.2 0.0 0.3 0.0 0.1 0.5 0.2 0.0 1.1 0.1 0.0 0.6 0.2 0.0 0.2 0.2 0.2 0.1 0.2 0.7 0.3 0.2 0.2 0.1 9.2 1.2 1.2 229.0 0.6 135.6 0.8 187.3 197.3 0.6 0.9 192.6 241.7 6.4 1.4 1.2 1.5 200.0 90.4 0.6 0.8 1.1 0.8 0.5 0.4 0.9 0.6 0.8 0.3 0.8 1.9 3.2 3.2 6.9 0.0 7.8 2.3 0.1 0.0 1.8 0.2 2.0 2.9 0.8 1.5 1.9 0.0 0.0 0.1 139.6 0.4 0.0 0.3 1.0 0.4 0.4 1.4 0.0 3.4 0.1 0.0 0.0 2.3 13.7 0.4 6.3 0.0 4.2 1.7 0.1 0.0 0.1 0.2 0.0 3.8 5.8 1.4 0.0 7.7 5.4 1.0 8.1 0.0 14.4 0.0 0.3 0.0 0.1 0.0 18.5 0.0 0.0 0.6 0.7 0.8 0.0 1.3 1.6 0.2 0.4 0.6 2.4 0.3 294.0 0.1 0.3 0.0 CD6 Tp120 ENSG00000013725 "CD6 molecule" P30203 11 60971680-61020377 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.6;lymphoid tissue: 43.1" "Cell type enhanced" "Detected in many" "dendritic cells: 25.7;NK-cells: 49.4;Plasma cells: 18.5;T-cells: 107.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 33 "gdT-cell: 27.7;MAIT T-cell: 24.7;memory CD4 T-cell: 51.4;memory CD8 T-cell: 48.4;naive CD4 T-cell: 34.4;naive CD8 T-cell: 25.2;T-reg: 25.5" "Lineage enriched" "Detected in many" 51 "T-cells: 51.4" "Group enriched" "Detected in some" 12 "JURKAT: 10.2;MOLT-4: 39.2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002489, CAB016252" Enhanced "Secreted to blood" NA NA 5270000 160000 "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "CAB002489: AB_563605, CAB016252: AB_631163" "prognostic favorable (1.95e-4)" "prognostic favorable (1.57e-5)" "unprognostic (4.47e-2)" "prognostic favorable (2.41e-4)" "unprognostic (2.06e-2)" "prognostic favorable (5.10e-6)" "unprognostic (8.45e-3)" "unprognostic (8.21e-3)" "unprognostic (2.87e-3)" "unprognostic (5.32e-3)" "unprognostic (2.07e-1)" "unprognostic (5.35e-1)" "prognostic unfavorable (1.82e-4)" "unprognostic (1.77e-1)" "unprognostic (4.95e-2)" "unprognostic (6.19e-2)" "unprognostic (5.96e-2)" 1.4 0.9 1.5 21.9 0.9 11.3 1.2 0.5 1.1 1.3 0.7 3.2 4.0 0.9 0.7 1.8 1.4 3.9 0.5 0.6 1.7 1.0 1.4 6.6 43.1 1.5 2.0 0.9 0.6 0.2 0.4 0.3 1.7 1.1 3.1 0.2 3.2 0.4 0.8 1.3 13.6 0.7 0.9 18.0 6.6 0.7 2.5 39.6 1.4 0.3 29.0 4.8 1.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.2 0.0 0.0 0.0 39.2 0.1 0.2 0.2 0.1 0.1 0.0 0.8 0.0 0.1 0.1 0.2 0.0 0.4 0.0 0.4 0.3 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 27.7 0.0 24.7 1.0 51.4 48.4 0.3 0.9 34.4 25.2 0.7 0.2 0.0 0.0 25.5 13.8 1.5 0.9 0.5 1.1 0.6 1.7 1.5 2.0 1.7 0.9 2.5 0.9 3.2 0.0 2.5 0.3 10.8 2.0 0.2 0.1 0.0 1.4 0.9 0.8 2.6 1.5 0.1 0.0 0.0 0.2 25.7 0.2 0.0 0.2 0.9 0.4 0.3 1.2 0.0 0.0 0.8 0.6 0.2 1.5 8.2 0.3 0.0 0.1 2.5 0.8 2.0 1.7 0.9 0.0 0.0 1.9 4.4 0.4 0.3 3.4 3.6 1.0 2.4 0.0 49.4 0.0 0.2 0.7 0.2 0.0 18.5 0.0 0.1 0.2 0.1 0.2 0.0 1.0 0.9 0.4 0.9 1.0 1.4 0.3 107.3 0.7 0.5 0.4 CDHR1 "CORD15, KIAA1775, PCDH21, RP65" ENSG00000148600 "Cadherin related family member 1" Q96JP9 10 84194537-84219621 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Cone-rod dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "retina: 313.8;skin 1: 214.0" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 379.5;Rod photoreceptor cells: 240.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 13.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 12 "NK-cell: 7.5" "Lineage enriched" "Detected in single" 12 "NK-cells: 7.5" "Cell line enhanced" "Detected in some" "HAP1: 10.2;HEK 293: 5.2;HEL: 6.3;K-562: 4.6;NTERA-2: 4.4;RPTEC TERT1: 16.3" "Region enriched" "Detected in many" 21 "olfactory bulb: 333.0" "Low region specificity" "Detected in all" HPA036819 Enhanced "Intracellular and membrane" NA NA 55000 "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA036819: AB_10671750" "unprognostic (8.91e-4)" "unprognostic (5.60e-2)" "unprognostic (1.64e-1)" "unprognostic (2.71e-2)" "unprognostic (2.63e-2)" "unprognostic (3.03e-2)" "unprognostic (6.40e-2)" "unprognostic (7.77e-2)" "unprognostic (1.41e-1)" "unprognostic (2.67e-1)" "unprognostic (6.69e-4)" "unprognostic (1.90e-1)" "unprognostic (5.51e-3)" "unprognostic (1.26e-1)" "unprognostic (2.27e-1)" "unprognostic (4.56e-3)" "unprognostic (5.07e-2)" 0.2 1.9 7.4 1.0 18.3 0.4 4.5 2.3 8.7 5.3 46.2 29.2 0.1 0.6 4.4 10.7 0.5 0.4 1.2 6.6 7.5 0.4 0.5 0.2 0.9 13.4 2.3 1.1 0.1 0.0 3.0 0.2 13.9 1.4 53.2 313.8 1.5 4.2 1.0 214.0 12.2 1.2 0.1 7.0 0.2 0.3 3.2 3.3 0.2 0.0 1.1 0.1 3.5 3.5 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 10.2 2.0 0.0 0.0 5.2 6.3 0.0 0.0 0.2 0.0 0.2 0.0 2.2 0.0 0.7 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 1.5 4.4 0.0 0.0 0.0 0.0 1.4 16.3 0.0 3.4 0.8 0.0 0.0 0.0 2.5 0.0 0.2 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.1 7.4 18.3 2.3 8.7 6.6 7.5 13.4 2.3 13.9 0.1 3.2 3.5 0.0 0.0 0.5 1.3 0.1 51.2 0.3 1.4 3.4 24.1 0.0 0.1 1.8 0.0 0.7 0.0 379.5 0.0 2.1 47.9 0.0 0.1 0.0 2.7 0.7 1.8 12.7 0.0 4.9 0.0 0.0 0.6 0.0 3.1 0.0 3.7 0.4 0.4 0.0 5.0 7.7 46.9 0.0 0.3 5.2 0.2 0.0 0.1 3.6 1.0 0.0 26.3 1.0 7.5 4.4 0.0 31.2 0.0 0.7 0.3 23.0 0.2 0.1 240.4 0.0 0.2 0.3 0.6 0.3 3.0 67.5 0.0 3.0 0.3 52.9 0.2 CDHR3 "CDH28, FLJ23834, FLJ44366" ENSG00000128536 "Cadherin related family member 3" Q6ZTQ4 7 105876796-106036432 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 46.4;fallopian tube: 108.8" "Cell type enhanced" "Detected in many" "Astrocytes: 170.7;Endometrial ciliated cells: 136.4;Excitatory neurons: 70.2;Inhibitory neurons: 63.8;Respiratory ciliated cells: 358.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.0;naive B-cell: 2.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "AF22: 5.7;Daudi: 6.5;WM-115: 4.9" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 11.8" HPA011218 Supported NA NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "HPA011218: AB_1078886" "unprognostic (4.38e-4)" "unprognostic (9.18e-2)" "unprognostic (8.16e-3)" "unprognostic (8.08e-3)" "unprognostic (5.23e-2)" "unprognostic (1.55e-1)" "unprognostic (3.43e-2)" "unprognostic (1.18e-3)" "unprognostic (2.99e-2)" "unprognostic (1.92e-1)" "unprognostic (2.28e-2)" "unprognostic (1.73e-2)" "unprognostic (1.16e-1)" "unprognostic (3.18e-1)" "unprognostic (2.77e-2)" "unprognostic (3.70e-3)" "unprognostic (3.51e-3)" 1.2 0.9 4.6 0.9 3.9 0.9 4.1 4.2 5.0 4.6 46.4 7.5 1.9 1.7 3.2 0.5 108.8 0.2 1.7 5.7 2.3 2.0 2.1 14.2 0.7 9.8 20.4 2.4 1.0 0.0 1.6 0.1 7.8 0.9 1.6 6.7 0.4 0.6 0.8 0.7 4.7 3.2 7.0 0.2 9.3 0.5 5.6 0.1 2.6 0.4 0.9 0.7 0.8 5.6 0.1 0.3 5.7 0.7 1.5 2.1 0.1 0.3 0.3 0.3 0.1 0.0 0.1 6.5 0.0 0.3 0.6 0.0 1.4 0.0 0.2 0.4 0.8 0.0 0.2 0.7 0.0 0.1 0.2 0.6 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.1 1.1 2.2 0.4 0.0 0.0 0.2 0.1 0.1 0.4 2.1 0.0 0.4 0.3 0.8 0.0 0.0 0.2 1.0 0.2 1.3 0.0 0.0 0.0 2.1 0.1 0.1 4.9 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 2.9 0.1 0.0 0.9 0.3 0.1 0.1 0.3 0.1 4.6 3.9 4.2 5.0 5.7 2.3 9.8 20.4 7.8 7.0 5.6 5.6 2.5 3.2 10.4 170.7 1.7 2.7 1.6 9.5 2.8 6.4 1.8 3.4 1.4 5.7 37.6 0.0 0.0 0.6 2.8 2.0 5.9 0.7 8.5 136.4 1.4 1.8 29.9 0.0 70.2 0.6 0.3 2.8 15.3 2.9 3.8 3.8 0.0 2.9 0.1 0.0 63.8 4.9 8.2 0.0 2.7 3.8 2.8 0.7 8.8 16.9 0.0 10.2 6.2 4.0 4.3 0.2 3.3 1.5 1.4 0.7 5.0 6.2 358.4 1.3 6.6 2.2 8.8 1.2 3.2 0.6 2.0 0.3 2.4 1.4 3.0 0.7 CEACAM4 CGM7 ENSG00000105352 "CEA cell adhesion molecule 4" O75871 19 41618971-41627074 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 21.3;lymphoid tissue: 32.6" "Cell type enhanced" "Detected in some" "Kupffer cells: 41.1;Macrophages: 20.9;monocytes: 9.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "neutrophil: 122.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 122.7" "Cell line enriched" "Detected in single" 6 "U-937: 4.1" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (1.10e-2)" "unprognostic (1.52e-2)" "unprognostic (1.24e-1)" "unprognostic (4.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.83e-2)" "unprognostic (9.11e-2)" "unprognostic (5.59e-2)" "unprognostic (1.79e-2)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (2.17e-1)" "unprognostic (2.09e-9)" "unprognostic (3.65e-2)" "unprognostic (2.95e-2)" "unprognostic (1.47e-1)" "unprognostic (4.34e-1)" 2.1 0.5 0.1 4.8 0.1 21.3 0.5 0.1 0.2 0.4 0.2 0.7 0.3 0.3 0.8 1.0 1.0 1.0 0.8 0.1 0.1 0.8 1.0 5.7 0.9 0.2 0.2 0.2 1.2 0.0 0.3 0.3 0.2 1.1 0.2 0.0 0.8 0.0 0.2 0.3 1.8 1.0 0.1 32.6 0.8 0.1 0.2 0.3 0.4 0.6 0.6 0.7 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 30.1 5.6 0.0 23.1 0.1 0.7 1.2 0.0 23.3 0.0 0.7 0.0 122.7 0.0 9.9 0.2 11.3 12.1 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.2 0.1 0.2 0.2 0.1 0.0 3.9 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 3.1 0.0 0.0 0.0 0.0 41.1 1.6 0.2 0.0 20.9 1.8 1.9 9.2 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 CEACAM8 "CD66b, CGM6" ENSG00000124469 "CEA cell adhesion molecule 8" P31997 19 42580243-42595055 "CD markers, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "bone marrow: 217.6" "Cell type enhanced" "Detected in single" "Paneth cells: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "neutrophil: 1.6;non-classical monocyte: 1.2" "Group enriched" "Detected in many" 6 "granulocytes: 1.6;monocytes: 1.2" "Not detected" "Not detected" CAB033676 Approved "Intracellular and membrane" NA NA 9200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "CAB033676: AB_1125678" "unprognostic (2.01e-1)" "unprognostic (4.52e-2)" "unprognostic (3.31e-1)" "unprognostic (6.30e-2)" "unprognostic (2.68e-1)" "unprognostic (1.62e-1)" "unprognostic (1.71e-2)" "unprognostic (7.77e-2)" "unprognostic (9.62e-2)" 0.2 0.0 0.3 0.2 0.2 217.6 0.0 0.3 0.4 0.0 0.0 0.4 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.2 1.7 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.4 0.2 0.4 0.0 0.1 0.5 0.1 0.0 0.0 6.0 0.0 0.1 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.2 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.2 0.1 0.3 0.2 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 1.6 0.2 1.2 0.0 0.0 2.7 0.3 0.2 0.3 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 CEBPA "C/EBP-alpha, CEBP" ENSG00000245848 "CCAAT enhancer binding protein alpha" P49715 19 33299934-33302534 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 98.7;liver: 194.7;skin 1: 118.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 91.6;Hepatocytes: 106.5;Hofbauer cells: 87.0;Suprabasal keratinocytes: 171.8;Syncytiotrophoblasts: 212.3" "Cancer enhanced" "Detected in all" "liver cancer: 70.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 16.0;classical monocyte: 7.1;intermediate monocyte: 12.3;myeloid DC: 5.1;non-classical monocyte: 15.7" "Group enriched" "Detected in many" 15 "dendritic cells: 5.1;granulocytes: 16.0;monocytes: 15.7" "Cell line enhanced" "Detected in many" "BEWO: 196.9;Hep G2: 110.9;NB-4: 114.1;THP-1: 407.7;U-937: 130.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052734, HPA065037, HPA067937" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA052734: AB_2681931, HPA065037: AB_2685410, HPA067937: AB_2685927" "unprognostic (1.80e-1)" "unprognostic (7.62e-3)" "unprognostic (2.09e-3)" "unprognostic (2.21e-2)" "unprognostic (3.38e-1)" "unprognostic (3.99e-2)" "unprognostic (1.94e-1)" "unprognostic (2.43e-3)" "unprognostic (5.95e-2)" "unprognostic (3.96e-2)" "unprognostic (3.09e-1)" "unprognostic (9.45e-2)" "unprognostic (8.02e-3)" "unprognostic (2.19e-1)" "unprognostic (1.98e-1)" "unprognostic (2.49e-2)" "unprognostic (2.72e-2)" 98.7 2.9 16.2 5.7 17.9 22.6 67.7 18.3 26.9 8.7 10.4 21.0 21.2 2.9 0.8 20.9 4.3 3.0 2.8 15.7 18.8 3.6 194.7 25.5 9.1 27.4 22.4 1.3 9.7 26.8 2.6 16.0 21.3 8.8 11.5 0.6 9.8 3.4 19.1 118.7 20.8 2.5 25.7 7.7 12.5 1.0 24.5 4.1 6.5 4.5 6.3 8.7 14.8 34.8 2.5 5.1 0.1 7.1 55.8 0.0 196.9 0.1 1.5 0.1 0.0 24.8 0.1 0.0 3.0 0.0 1.1 9.4 5.8 0.6 0.0 35.8 7.2 0.1 0.1 110.9 0.9 36.6 42.1 2.2 25.4 0.0 0.2 0.0 0.0 2.8 2.4 0.0 0.0 12.7 0.2 114.1 5.0 61.8 2.7 0.0 0.4 1.1 0.2 17.7 0.4 1.7 0.7 0.5 0.8 6.2 13.7 407.7 0.1 0.1 0.8 0.1 0.9 0.4 0.0 0.2 0.0 130.9 0.0 16.0 7.1 0.0 0.8 12.3 0.7 0.0 0.1 0.5 5.1 0.1 0.2 0.4 2.5 0.0 15.7 0.2 0.0 2.1 16.2 17.9 18.3 26.9 15.7 18.8 27.4 22.4 21.3 25.7 24.5 34.8 5.4 16.0 37.8 0.0 2.8 37.3 20.8 3.3 22.2 0.7 6.2 12.2 0.4 57.2 5.1 0.0 0.0 40.3 14.4 91.6 3.9 0.5 0.0 0.8 0.8 4.9 4.2 5.7 1.9 5.8 44.3 9.5 12.8 1.3 1.3 0.0 2.2 106.5 87.0 0.0 0.3 24.8 4.1 35.0 27.4 0.2 3.1 42.9 5.4 17.8 28.2 8.4 6.2 1.0 0.4 1.9 30.6 1.5 2.0 15.1 42.5 4.9 5.1 0.5 0.0 4.1 3.1 0.2 0.7 29.7 171.8 212.3 5.0 0.3 51.5 12.2 CERS4 "FLJ12089, LASS4, Trh1" ENSG00000090661 "Ceramide synthase 4" Q9HA82 19 8206736-8262421 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 71.3;Muller glia cells: 150.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 55.1;NB-4: 99.8;U-937: 61.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033734, HPA054729" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 5: Muller glia cells - Visual perception" "Nucleoplasm, Vesicles" "CAB033734: AB_2132977, HPA054729: " "unprognostic (5.96e-2)" "prognostic favorable (2.71e-4)" "unprognostic (2.46e-2)" "unprognostic (2.82e-2)" "unprognostic (1.30e-1)" "prognostic favorable (7.83e-4)" "unprognostic (1.74e-1)" "prognostic favorable (3.45e-5)" "unprognostic (1.48e-2)" "unprognostic (3.32e-1)" "prognostic favorable (8.05e-4)" "unprognostic (1.77e-1)" "prognostic favorable (9.63e-5)" "unprognostic (6.08e-3)" "unprognostic (2.69e-2)" "unprognostic (2.91e-2)" "unprognostic (8.08e-3)" 13.6 13.0 31.8 10.0 38.9 3.4 31.1 26.6 37.1 35.9 18.7 17.7 6.3 21.5 61.5 64.3 21.3 11.2 14.8 35.3 25.2 27.8 57.7 19.4 19.9 36.9 30.5 22.0 89.1 29.0 22.2 1.9 30.8 32.9 3.9 36.9 55.0 17.6 3.1 47.7 15.2 12.0 26.8 17.7 26.8 11.5 30.7 13.1 51.9 5.3 20.4 18.4 32.7 44.0 0.4 2.1 2.1 25.0 0.8 0.2 1.7 3.1 8.4 3.7 1.7 19.5 1.7 40.0 27.4 0.0 9.6 13.6 16.4 0.4 1.7 35.5 12.4 7.6 0.1 55.1 31.6 0.0 21.3 12.3 20.7 8.8 18.9 10.5 0.3 17.7 5.9 1.2 0.0 0.8 2.6 99.8 25.4 0.2 8.7 49.1 0.8 3.0 6.3 0.0 9.3 12.2 4.3 0.7 14.5 16.7 18.8 8.8 0.2 2.9 7.8 18.6 0.1 24.5 21.1 32.0 0.1 61.9 2.8 12.3 7.1 27.4 7.5 3.9 5.7 19.8 4.3 4.6 4.1 17.7 3.9 3.8 22.4 22.4 2.4 3.9 5.5 5.8 31.8 38.9 26.6 37.1 35.3 25.2 36.9 30.5 30.8 26.8 30.7 44.0 3.2 6.4 10.7 27.1 31.2 18.0 13.2 12.0 15.4 24.5 47.0 28.8 4.1 22.8 22.2 1.8 18.8 3.4 17.2 0.2 7.9 20.0 1.7 7.9 11.2 8.6 23.9 4.0 38.3 30.5 0.9 15.7 3.1 7.6 12.7 14.4 8.2 71.3 16.4 11.8 24.4 1.3 8.2 7.1 7.2 7.3 14.3 6.7 26.6 16.9 19.6 150.3 27.8 47.7 48.1 9.4 2.5 16.1 12.4 40.6 0.4 44.6 27.8 29.5 6.6 6.9 13.8 1.0 1.6 20.6 25.9 2.9 15.7 2.7 2.5 11.9 CES3 "ES31, FLJ21736" ENSG00000172828 "Carboxylesterase 3" Q6UWW8 16 66961245-66975149 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.2;liver: 52.5;skeletal muscle: 24.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 120.1;Granulosa cells: 58.5;Hepatocytes: 53.4;Intestinal goblet cells: 32.0;Paneth cells: 67.0;Proximal enterocytes: 66.0;Undifferentiated cells: 44.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 7.4;Daudi: 8.5;JURKAT: 13.5;U-937: 7.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041008, HPA041307" Approved Approved "Nuclear membrane,Endoplasmic reticulum" "Intracellular and membrane" NA NA 1200000 "Cluster 52: Eosinophils - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear membrane, Endoplasmic reticulum" "HPA041008: AB_2677247, HPA041307: AB_2677400" "unprognostic (3.91e-3)" "unprognostic (1.22e-1)" "unprognostic (1.94e-2)" "unprognostic (8.99e-3)" "unprognostic (9.32e-2)" "unprognostic (7.84e-4)" "prognostic favorable (7.26e-5)" "unprognostic (5.67e-3)" "unprognostic (1.52e-1)" "unprognostic (2.17e-1)" "unprognostic (6.43e-2)" "unprognostic (1.84e-2)" "unprognostic (1.19e-2)" "unprognostic (2.18e-2)" "unprognostic (2.75e-1)" "unprognostic (3.31e-2)" "unprognostic (7.41e-2)" 0.8 0.5 3.1 3.2 2.7 0.9 2.3 2.5 2.9 1.3 1.3 38.2 30.0 0.7 0.2 4.2 2.9 0.9 0.7 3.8 2.0 12.2 52.5 0.7 0.3 3.3 2.7 0.6 4.1 1.0 1.9 0.6 3.5 0.5 31.3 0.6 12.0 0.3 24.7 1.2 23.7 1.2 1.4 0.4 7.7 1.1 2.2 0.2 0.4 1.5 0.2 0.1 0.8 2.2 0.4 3.1 0.3 7.4 0.2 0.2 1.2 0.2 0.2 0.3 0.5 0.5 3.8 8.5 2.4 0.0 0.2 0.6 1.1 0.5 0.1 1.5 5.5 4.3 1.3 2.6 0.0 0.9 0.7 0.3 0.9 0.8 0.1 0.2 0.0 13.5 2.8 1.7 0.3 1.1 1.4 1.4 1.5 2.6 0.4 1.3 0.7 1.3 0.1 0.4 0.4 0.8 0.2 5.8 0.2 0.6 5.0 6.5 0.3 0.4 2.4 0.7 0.2 0.9 3.6 1.3 0.3 7.2 0.2 0.2 0.1 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.1 0.0 3.1 2.7 2.5 2.9 3.8 2.0 3.3 2.7 3.5 1.4 2.2 2.2 0.1 3.2 6.7 0.7 0.4 0.5 0.0 1.3 1.2 0.2 9.1 5.7 1.4 2.8 0.9 0.0 0.0 0.0 0.0 120.1 0.0 0.2 0.5 3.2 0.3 0.2 19.7 0.0 1.8 0.9 0.0 0.2 11.7 4.4 1.3 58.5 0.4 53.4 0.3 0.0 2.9 32.0 0.0 3.2 0.9 5.4 0.0 0.9 0.0 0.0 0.0 0.4 0.0 1.5 0.1 1.0 67.0 1.2 0.1 0.1 66.0 9.9 4.8 0.2 0.0 0.6 0.2 2.3 2.9 1.1 0.3 0.0 0.4 0.1 44.3 0.2 CFH "ARMD4, ARMS1, FHL1, HF, HF1, HF2, HUS" ENSG00000000971 "Complement factor H" P08603 1 196652043-196747504 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Host-virus interaction, Immunity, Innate immunity" "Age-related macular degeneration, Cancer-related genes, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 1676.3" "Group enriched" "Detected in many" 4 "Fibroblasts: 448.0;Hepatocytes: 1114.8;Leydig cells: 283.9" "Cancer enriched" "Detected in all" 9 "liver cancer: 151.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 18.7" "Lineage enriched" "Detected in single" 26 "T-cells: 18.7" "Cell line enhanced" "Detected in many" "HHSteC: 123.1;HSkMC: 119.5;hTERT-RPE1: 374.9;RT4: 227.0" "CAB016385, CAB016769, HPA038922, HPA049176, HPA053326" Supported Approved Vesicles "Secreted to blood" NA NA 396000000000 100000000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB016385: AB_627572, CAB016769: , HPA038922: AB_2676271, HPA049176: AB_2680663, HPA053326: AB_2682113" "unprognostic (2.40e-1)" "unprognostic (9.86e-2)" "unprognostic (1.22e-1)" "unprognostic (8.39e-2)" "unprognostic (5.40e-3)" "unprognostic (1.80e-1)" "unprognostic (3.75e-3)" "unprognostic (7.40e-2)" "unprognostic (1.06e-1)" "unprognostic (1.04e-1)" "unprognostic (9.08e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.92e-6)" "unprognostic (6.50e-3)" "unprognostic (4.49e-3)" "unprognostic (1.73e-1)" "unprognostic (1.37e-1)" 125.3 42.1 18.1 32.7 21.5 1.3 66.9 20.0 29.6 76.8 43.0 51.0 30.5 12.8 15.9 63.8 24.2 133.6 301.5 18.1 18.6 25.5 1676.3 70.8 27.4 19.3 19.0 165.1 14.0 6.4 16.0 26.1 19.9 23.0 80.2 4.3 126.7 24.0 21.1 74.5 52.1 32.5 19.5 13.9 46.9 14.3 21.6 12.1 102.5 84.0 25.9 149.9 27.0 21.1 0.0 64.9 0.0 0.0 96.5 54.7 0.1 25.8 63.1 3.5 13.5 0.1 11.9 0.3 9.6 0.1 0.2 2.2 0.0 23.6 2.6 1.3 0.0 20.0 74.7 0.0 123.1 0.9 0.3 119.5 0.3 18.4 7.9 374.9 79.2 0.0 74.4 2.7 89.4 0.1 0.5 0.1 0.4 0.0 0.1 0.2 89.8 21.0 0.0 227.0 0.0 0.1 0.4 0.0 0.1 0.6 0.1 0.0 5.6 73.6 0.9 0.8 0.8 0.8 0.0 0.3 13.1 0.2 5.8 0.0 0.1 0.0 2.0 0.0 18.7 0.0 6.6 4.0 0.2 0.0 0.4 1.5 0.7 0.0 0.0 0.0 0.0 1.1 18.1 21.5 20.0 29.6 18.1 18.6 19.3 19.0 19.9 19.5 21.6 21.1 73.9 9.6 17.6 0.7 4.2 44.2 63.6 140.6 14.2 2.4 1.3 3.4 10.9 35.8 141.1 5.5 0.0 0.0 3.1 0.1 0.0 6.2 2.6 2.3 3.8 49.8 0.0 52.6 0.6 0.8 0.0 448.0 8.6 1.9 3.8 6.9 47.8 1114.8 1.1 0.0 1.0 0.0 14.2 43.8 62.1 7.4 283.9 5.7 44.4 38.4 0.3 0.3 0.0 0.0 0.2 5.3 0.0 138.8 2.6 13.0 0.0 0.5 115.6 1.4 6.6 94.2 59.6 1.4 1.0 10.9 38.2 0.1 13.2 26.3 0.0 61.5 CFHR2 "CFHL2, FHR2, HFL3" ENSG00000080910 "Complement factor H related 2" P36980 1 196943738-196959622 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2752 "liver: 1311.8" "Cell type enriched" "Detected in some" 14 "Hepatocytes: 38.5" "Cancer enriched" "Detected in single" 175 "liver cancer: 8.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038915, HPA040726, HPA049813" Supported "Secreted to blood" NA NA 4800000000 "Cluster 6: Non-specific - Transcription" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 15: Hepatocytes - Hemostasis" "HPA038915: AB_2676269, HPA040726: AB_2677101, HPA049813: AB_2680895" "unprognostic (1.25e-2)" 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.4 1311.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 38.5 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 CFHR4 "CFHL4, FHR-4, FHR4" ENSG00000134365 "Complement factor H related 4" Q92496 1 196888014-196918713 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 432 "liver: 123.9" "Cell type enriched" "Detected in some" 28 "Hepatocytes: 62.6" "Cancer enriched" "Detected in single" 145 "liver cancer: 13.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/70: 1.3" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 170000000 "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (5.97e-1)" "prognostic favorable (1.57e-6)" "unprognostic (1.89e-1)" "unprognostic (4.79e-2)" "unprognostic (1.26e-1)" "unprognostic (1.68e-2)" "unprognostic (4.71e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 123.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.7 0.0 1.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.3 2.2 62.6 0.0 0.0 0.5 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 CFHR5 "CFHL5, FHR-5, FHR5" ENSG00000134389 "Complement factor H related 5" Q9BXR6 1 196977556-197009678 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1675 "liver: 167.5" "Cell type enriched" "Detected in some" 19 "Hepatocytes: 102.7" "Cancer enriched" "Detected in single" 396 "liver cancer: 57.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038915, HPA040726" Supported "Secreted to blood" NA NA 1900000000 "Cluster 62: Liver - Hemostasis" "Cluster 15: Hepatocytes - Hemostasis" "HPA038915: AB_2676269, HPA040726: AB_2677101" "unprognostic (9.12e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 167.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 102.7 0.0 0.0 0.1 0.0 0.0 3.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 CFI "C3b-INA, FI, IF, KAF" ENSG00000205403 "Complement factor I" P05156 4 109740694-109801999 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 1098.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 108.7;Hepatocytes: 592.5;Muller glia cells: 147.8;Proximal tubular cells: 223.6" "Cancer enhanced" "Detected in all" "liver cancer: 90.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 106.1;Hep G2: 179.8;HSkMC: 67.4;RPTEC TERT1: 190.6" "HPA001143, CAB016777, HPA024061" Supported "Secreted to blood" NA NA 12000000000 "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB016777: , HPA001143: AB_1078555, HPA024061: AB_1847129" "unprognostic (1.04e-1)" "unprognostic (5.79e-2)" "unprognostic (1.68e-1)" "unprognostic (6.32e-2)" "unprognostic (1.55e-2)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" "unprognostic (3.00e-1)" "unprognostic (2.00e-2)" "unprognostic (5.42e-3)" "unprognostic (1.41e-1)" "unprognostic (3.61e-1)" "unprognostic (8.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (6.06e-4)" 45.1 50.2 8.1 12.6 8.2 0.1 17.4 7.7 13.2 36.8 10.4 7.4 38.0 39.2 80.3 9.3 74.0 73.0 25.0 8.3 9.6 224.9 1098.8 50.7 8.9 15.6 10.2 32.1 26.0 3.1 8.4 24.1 10.7 8.3 6.4 53.0 15.0 26.7 3.9 2.7 22.3 24.3 10.5 33.1 14.4 8.8 9.2 2.3 14.5 4.6 7.5 34.1 8.3 10.6 0.0 0.6 0.0 0.3 0.0 0.2 0.1 1.5 1.4 0.1 0.2 0.0 106.1 0.0 32.9 0.0 0.5 0.0 0.0 0.0 0.0 34.8 0.7 0.0 0.4 179.8 6.2 0.3 0.0 67.4 0.0 0.1 0.0 3.6 4.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 190.6 0.5 0.0 0.3 1.6 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.6 0.0 0.0 0.0 0.1 18.8 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 8.2 7.7 13.2 8.3 9.6 15.6 10.2 10.7 10.5 9.2 10.6 48.1 12.8 50.9 3.6 4.0 1.0 12.2 15.2 0.6 3.4 2.1 5.6 2.3 108.7 36.2 64.4 2.1 0.1 0.3 1.7 31.3 69.3 0.2 34.1 46.4 57.7 0.0 2.7 0.3 30.9 0.2 34.3 8.2 33.6 3.8 72.1 55.0 592.5 0.7 1.7 0.2 1.9 0.0 16.7 1.5 0.8 16.8 2.0 0.0 4.7 1.6 147.8 0.0 0.0 0.3 30.8 2.4 0.0 0.0 3.8 17.0 223.6 8.4 7.3 0.0 1.3 9.4 1.6 0.5 1.9 1.1 0.3 3.4 18.5 4.1 12.6 CGN KIAA1319 ENSG00000143375 Cingulin Q9P2M7 1 151510510-151538692 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 56.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 118.6;Distal enterocytes: 173.2;Paneth cells: 108.7;Proximal enterocytes: 88.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 91.4;CAPAN-2: 59.1;OE19: 58.6;RT4: 44.0" "Low region specificity" "Detected in many" "CAB017193, HPA027586, HPA027587, HPA027657" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "CAB017193: , HPA027586: AB_10600208, HPA027587: AB_10601884, HPA027657: AB_10611527" "unprognostic (1.57e-1)" "unprognostic (4.30e-2)" "unprognostic (1.12e-1)" "unprognostic (8.74e-3)" "unprognostic (1.02e-1)" "unprognostic (3.01e-1)" "unprognostic (1.98e-1)" "unprognostic (8.38e-2)" "unprognostic (4.61e-1)" "unprognostic (2.11e-2)" "unprognostic (2.96e-3)" "unprognostic (7.10e-2)" "prognostic favorable (5.84e-10)" "unprognostic (2.66e-1)" "unprognostic (3.00e-1)" "unprognostic (8.28e-2)" "unprognostic (2.10e-2)" 5.8 1.1 1.9 6.0 3.3 0.4 9.0 8.5 3.3 4.9 6.5 37.2 52.7 1.4 1.5 8.6 13.2 13.6 0.6 2.0 3.7 12.2 32.1 27.3 0.4 5.5 3.0 2.0 24.2 32.1 3.7 1.6 5.6 10.1 25.1 3.7 21.1 7.0 0.2 17.9 56.4 1.5 1.7 0.4 30.4 6.6 3.4 0.7 4.9 0.1 2.3 8.3 6.2 6.7 28.9 3.2 2.7 4.6 0.0 0.0 35.4 0.1 0.1 0.8 0.9 91.4 59.1 1.3 9.4 0.0 4.9 27.0 8.6 5.0 0.6 17.3 6.0 2.4 1.3 1.8 0.0 0.4 3.6 0.0 1.0 1.3 0.7 0.0 0.3 7.8 1.2 8.1 0.0 26.8 5.0 0.6 22.9 58.6 2.5 5.4 2.8 4.3 17.9 44.0 8.9 4.4 1.8 27.1 1.0 10.3 33.5 0.3 0.5 0.3 8.3 0.5 1.2 7.7 8.4 5.2 0.3 3.3 2.4 0.2 0.1 0.0 0.5 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.4 0.2 0.1 0.1 0.1 0.0 1.9 3.3 8.5 3.3 2.0 3.7 5.5 3.0 5.6 1.7 3.4 6.7 0.1 118.6 33.3 2.3 0.2 0.3 3.3 5.9 0.6 4.3 14.9 9.1 0.7 24.3 22.4 3.7 0.0 3.5 0.5 173.2 0.0 21.5 0.3 13.8 2.1 0.6 10.3 2.7 0.8 25.4 0.3 2.3 54.6 27.3 0.0 0.5 0.0 29.6 0.3 0.0 10.4 32.7 8.2 0.0 0.4 1.2 0.6 0.5 3.6 0.0 2.1 13.5 0.0 3.5 11.7 49.5 108.7 0.7 0.5 11.9 88.7 3.0 46.8 1.5 0.0 0.1 1.0 1.5 6.9 4.2 1.8 0.4 0.6 1.8 27.2 18.3 CHAD SLRR4A ENSG00000136457 Chondroadherin O15335 17 50464496-50468906 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 36.2;pancreas: 32.6" "Cell type enhanced" "Detected in some" "Breast glandular cells: 4.6;Breast myoepithelial cells: 2.4;Distal enterocytes: 3.3;Gastric mucus-secreting cells: 4.6;Hepatocytes: 2.4;Intestinal goblet cells: 4.3;Oligodendrocyte precursor cells: 5.5;Paneth cells: 2.5;Proximal enterocytes: 2.6" "Group enriched" "Detected in many" 5 "breast cancer: 23.7;liver cancer: 10.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 53 "memory B-cell: 21.5;naive B-cell: 8.0" "Lineage enriched" "Detected in single" 76 "B-cells: 21.5" "Cell line enhanced" "Detected in some" "RT4: 4.0;SCLC-21H: 8.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA018241 Enhanced "Secreted to extracellular matrix" NA NA 22000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA018241: AB_1846612" "prognostic favorable (7.68e-4)" "unprognostic (4.34e-2)" "unprognostic (1.24e-1)" "unprognostic (9.67e-3)" "unprognostic (1.92e-1)" "unprognostic (3.06e-3)" "prognostic favorable (1.59e-4)" "unprognostic (1.51e-2)" "unprognostic (4.75e-2)" "unprognostic (3.73e-3)" "unprognostic (1.53e-1)" "unprognostic (1.39e-1)" "unprognostic (1.92e-1)" "unprognostic (2.52e-1)" "unprognostic (1.84e-2)" "unprognostic (1.51e-3)" "unprognostic (1.41e-3)" 2.1 14.1 6.2 0.7 7.9 0.3 9.6 17.4 7.3 21.8 3.9 6.7 7.6 0.5 0.1 1.8 0.8 1.5 1.7 5.5 6.3 2.4 36.2 1.6 0.6 5.6 4.9 3.1 32.6 0.0 1.3 0.5 5.7 1.9 4.0 0.5 21.3 0.2 14.5 8.5 10.3 0.1 5.1 1.1 10.8 1.2 5.8 0.2 4.2 0.9 0.2 1.2 1.6 5.4 1.0 0.8 0.7 0.6 0.0 0.0 2.1 0.1 0.0 0.0 0.0 1.5 0.8 0.1 0.2 0.0 0.2 1.5 0.0 0.0 0.0 0.6 0.7 1.2 0.7 1.5 0.0 0.4 1.1 0.0 0.0 0.0 0.0 1.7 0.0 0.4 0.1 0.3 0.0 0.5 0.0 0.7 0.1 0.1 0.7 0.9 0.1 1.5 0.0 4.0 8.5 0.2 0.1 0.3 0.0 0.3 0.3 0.2 0.9 2.1 0.4 0.1 0.0 1.4 0.0 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.5 0.2 0.0 0.1 8.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.6 6.2 7.9 17.4 7.3 5.5 6.3 5.6 4.9 5.7 5.1 5.8 5.4 0.0 0.0 0.0 1.3 1.0 0.3 0.2 0.3 0.0 0.0 4.6 2.4 0.2 1.5 0.2 0.0 0.0 0.1 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 4.6 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.2 4.3 0.0 0.3 0.4 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 5.5 0.1 0.0 2.5 0.0 1.1 0.2 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.4 CHADL SLRR4B ENSG00000100399 "Chondroadherin like" Q6NUI6 22 41229510-41240931 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 109.6" "Cell type enhanced" "Detected in many" "Muller glia cells: 40.3;Oligodendrocytes: 83.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 11.8;Hep G2: 3.4;hTCEpi: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA005696, HPA024654" Uncertain "Secreted to extracellular matrix" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 28: BEWO - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" "HPA005696: AB_1079724, HPA024654: AB_1846615" "unprognostic (6.14e-2)" "unprognostic (4.42e-3)" "unprognostic (1.49e-1)" "unprognostic (6.45e-3)" "unprognostic (1.32e-1)" "unprognostic (9.51e-3)" "unprognostic (2.20e-2)" "prognostic favorable (1.56e-4)" "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (2.83e-3)" "unprognostic (1.51e-2)" "unprognostic (4.67e-8)" "unprognostic (8.36e-3)" "unprognostic (4.10e-1)" "unprognostic (3.40e-1)" "unprognostic (4.09e-2)" 2.6 4.7 25.4 0.5 62.4 1.0 2.6 57.5 43.9 3.5 5.2 12.4 1.5 1.3 1.5 4.2 2.2 2.7 16.5 25.1 32.4 2.1 3.1 2.1 0.8 69.6 51.8 2.6 3.5 0.5 4.3 0.6 61.3 6.5 0.3 1.0 11.3 3.8 2.2 6.1 3.4 0.8 43.4 0.7 5.0 3.5 56.3 1.7 4.4 1.6 0.4 2.9 3.6 109.6 0.6 0.2 0.2 0.3 0.1 0.1 11.8 0.4 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.6 0.1 0.5 0.0 0.6 0.0 0.1 0.2 0.0 0.3 3.4 0.4 0.1 0.1 1.0 3.4 0.3 0.0 0.1 0.4 0.2 0.0 0.5 0.0 0.3 0.2 0.6 0.3 0.3 0.4 0.1 0.5 0.2 0.2 0.3 0.7 0.1 1.3 0.2 0.1 0.0 0.0 1.2 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.1 1.6 0.0 0.1 0.4 0.1 0.4 0.2 0.0 0.1 0.2 0.1 0.0 0.4 0.1 0.2 0.0 0.0 1.2 0.0 0.3 25.4 62.4 57.5 43.9 25.1 32.4 69.6 51.8 61.3 43.4 56.3 109.6 2.7 6.4 2.2 8.1 0.2 4.0 10.2 1.8 17.6 1.4 7.3 6.5 3.5 2.8 1.7 3.7 0.0 3.0 0.4 0.8 7.9 2.0 18.6 2.5 0.6 1.3 3.0 0.0 2.8 1.2 6.4 5.5 2.6 1.6 0.0 3.2 2.5 2.5 5.1 0.0 2.5 0.8 2.0 0.8 2.1 12.0 3.7 3.4 17.8 1.9 0.4 40.3 0.0 12.5 83.1 0.8 1.0 3.0 0.3 3.7 1.3 5.9 4.1 1.6 0.0 2.5 1.2 0.3 0.8 6.5 3.7 1.5 0.5 0.7 1.4 6.5 CHN2 "ARHGAP3, RhoGAP3" ENSG00000106069 "Chimerin 2" P52757 7 29146569-29514328 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 101.0;intestine: 70.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 307.9;Early spermatids: 130.6;Excitatory neurons: 139.5;Late spermatids: 118.1;Microglial cells: 145.2;Oligodendrocytes: 496.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 37.4;HMC-1: 68.3" "HPA018989, HPA019026" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Nuclear bodies" "HPA018989: AB_1846681, HPA019026: " "unprognostic (3.88e-2)" "unprognostic (2.36e-1)" "unprognostic (6.87e-2)" "unprognostic (2.56e-1)" "unprognostic (1.52e-1)" "unprognostic (8.12e-2)" "unprognostic (6.87e-2)" "unprognostic (1.19e-1)" "unprognostic (6.64e-2)" "unprognostic (4.71e-2)" "unprognostic (7.54e-2)" "unprognostic (7.85e-2)" "unprognostic (1.61e-2)" "unprognostic (1.68e-1)" "unprognostic (1.18e-1)" "unprognostic (1.15e-2)" "unprognostic (1.58e-3)" 4.6 6.3 19.0 5.3 33.0 2.2 3.4 101.0 37.5 10.2 12.4 8.5 70.1 4.1 2.3 2.6 8.0 7.0 11.7 22.2 27.1 13.1 37.9 5.6 3.1 30.4 26.5 20.2 25.1 0.5 3.4 10.8 33.2 8.0 9.8 51.5 2.7 4.1 4.7 1.9 57.9 4.3 24.2 8.2 6.6 2.5 25.4 3.8 7.8 1.4 2.5 6.3 3.2 59.6 0.3 0.8 3.0 0.0 0.0 0.0 19.0 0.0 0.0 0.7 0.0 10.4 2.9 0.9 6.0 0.2 1.2 5.2 10.1 0.1 0.0 18.1 3.8 37.4 1.7 18.4 0.2 0.0 68.3 0.0 6.4 0.0 0.7 0.0 3.5 5.9 1.5 0.5 0.0 0.4 11.2 0.4 1.2 6.8 3.4 0.8 0.0 2.0 18.2 12.0 18.3 1.4 3.9 5.8 10.2 10.7 0.7 2.0 0.4 1.0 0.3 0.1 0.4 3.6 15.2 0.0 0.3 2.2 1.2 4.4 11.6 0.1 2.8 12.7 1.9 0.3 0.4 2.1 10.1 0.1 0.4 1.1 0.5 9.6 7.3 1.1 0.0 3.6 19.0 33.0 101.0 37.5 22.2 27.1 30.4 26.5 33.2 24.2 25.4 59.6 3.3 6.4 3.6 5.5 2.0 2.7 0.8 0.2 0.6 307.9 0.3 0.3 14.1 5.7 2.0 3.7 43.8 24.6 6.1 15.3 0.0 0.5 130.6 8.8 0.3 8.5 39.4 9.5 139.5 2.1 33.5 3.8 12.2 2.7 23.5 2.2 3.9 84.4 18.5 6.7 28.8 24.0 2.0 29.0 33.1 118.1 5.0 20.5 17.8 145.2 29.3 11.7 22.6 10.1 496.8 0.2 14.3 4.9 1.3 1.0 107.8 2.3 7.6 15.9 0.0 5.4 1.1 2.6 6.2 0.2 0.6 16.4 14.4 0.7 23.6 1.1 CIAO2A "CIA2A, FAM96A, FLJ22875" ENSG00000166797 "Cytosolic iron-sulfur assembly component 2A" Q9H5X1 15 64072565-64093857 "Predicted intracellular proteins" "Chromosome partition" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 262.4" "Group enriched" "Detected in some" 9 "Cardiomyocytes: 74.8;Cytotrophoblasts: 116.5;Extravillous trophoblasts: 100.6;Hofbauer cells: 218.2;Syncytiotrophoblasts: 88.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040459, HPA063729" Approved Enhanced Nucleoplasm,Cytosol "Intracellular and membrane" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" "HPA040459: AB_10796456, HPA063729: AB_2685105" "unprognostic (1.15e-1)" "unprognostic (8.49e-2)" "unprognostic (6.59e-2)" "unprognostic (3.58e-1)" "unprognostic (1.30e-1)" "unprognostic (8.07e-2)" "unprognostic (4.06e-3)" "unprognostic (5.02e-2)" "unprognostic (7.16e-2)" "unprognostic (5.87e-2)" "unprognostic (1.04e-1)" "unprognostic (6.48e-3)" "unprognostic (8.06e-3)" "unprognostic (1.81e-1)" "unprognostic (2.58e-1)" "unprognostic (2.11e-2)" "unprognostic (1.50e-2)" 27.8 68.6 23.1 53.6 26.0 70.7 48.5 25.7 26.7 31.5 39.1 82.8 107.9 22.6 41.1 30.1 32.1 43.0 78.0 22.0 24.6 81.3 262.4 43.4 105.3 26.1 24.0 20.6 59.8 75.5 24.6 65.5 26.6 39.1 68.4 24.7 44.0 26.8 125.5 19.4 86.8 23.8 26.4 52.8 68.8 20.7 26.9 60.3 80.2 97.4 66.9 46.3 20.3 32.0 114.6 168.6 104.3 71.7 91.7 110.7 61.2 92.7 105.4 120.2 133.5 157.7 172.9 186.9 157.4 56.2 155.7 118.3 197.9 90.2 95.4 171.3 124.2 156.2 137.7 161.2 70.7 240.5 123.1 90.8 87.2 76.7 67.6 84.5 130.1 118.5 222.3 148.8 89.5 197.8 100.1 202.8 144.6 148.9 96.3 154.5 139.8 410.4 154.3 127.0 112.2 87.5 76.8 150.9 180.6 113.9 120.6 243.6 83.0 98.2 129.4 104.7 193.6 144.4 353.8 186.4 109.5 429.3 96.9 122.4 255.8 117.0 67.3 254.1 83.0 346.0 94.8 88.1 231.6 345.5 75.5 74.4 132.0 86.9 228.3 386.5 146.1 269.0 23.1 26.0 25.7 26.7 22.0 24.6 26.1 24.0 26.6 26.4 26.9 32.0 10.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.8 0.0 0.0 0.0 0.0 116.5 10.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 100.6 13.2 0.0 0.0 0.0 0.0 0.0 0.0 218.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 88.8 2.0 0.0 0.0 0.0 CILP HsT18872 ENSG00000138615 "Cartilage intermediate layer protein" O75339 15 65194760-65211473 "Disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.9;Fibroblasts: 138.1;Leydig cells: 231.5;Peritubular cells: 57.6;Theca cells: 83.5" "Cancer enhanced" "Detected in many" "breast cancer: 30.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 4.2;ASC TERT1: 2.5;EFO-21: 1.1;HSkMC: 6.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA003195 Uncertain "Secreted to extracellular matrix" NA NA 13000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA003195: AB_1078524" "unprognostic (2.21e-2)" "unprognostic (3.43e-2)" "unprognostic (4.22e-2)" "unprognostic (7.18e-2)" "unprognostic (2.94e-1)" "unprognostic (2.28e-1)" "unprognostic (2.60e-1)" "unprognostic (1.14e-1)" "unprognostic (1.88e-2)" "unprognostic (3.00e-2)" "unprognostic (1.84e-1)" "unprognostic (1.27e-1)" "unprognostic (2.31e-13)" "unprognostic (5.10e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (4.68e-3)" 49.8 0.8 0.2 9.5 0.2 0.1 21.9 0.3 0.3 44.9 0.1 20.3 2.3 13.8 3.6 11.0 15.8 36.8 27.4 0.2 0.2 1.0 1.6 2.9 1.6 0.2 0.2 7.5 3.0 0.3 0.7 2.5 0.2 3.1 6.9 0.5 9.4 4.8 15.5 14.0 22.6 51.0 0.2 0.6 8.3 12.1 0.2 1.8 2.4 32.9 0.8 26.9 28.1 0.2 0.0 0.0 0.0 0.0 4.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 8.1 0.0 0.0 0.0 0.0 5.2 0.1 0.2 0.0 0.9 0.4 0.5 2.1 0.0 0.4 1.8 0.0 0.0 0.2 0.1 0.0 0.1 1.7 1.2 42.9 1.5 0.0 0.0 0.3 0.0 0.0 138.1 4.1 1.7 0.0 0.1 2.2 0.1 0.1 0.0 0.6 0.1 2.0 0.0 11.9 7.1 231.5 1.7 1.8 1.9 0.0 0.2 0.0 1.0 0.3 0.0 0.0 57.6 0.3 0.1 0.0 0.0 0.0 0.1 0.0 14.7 6.6 0.6 0.3 0.1 6.1 0.0 1.6 83.5 0.2 0.0 CLDN14 DFNB29 ENSG00000159261 "Claudin 14" O95500 21 36460621-36576569 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 22 "kidney: 13.8;liver: 39.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 7.2;Distal tubular cells: 19.6;Ductal cells: 11.8;Exocrine glandular cells: 8.2;Hepatocytes: 22.2;Pancreatic endocrine cells: 21.3" "Cancer enriched" "Detected in many" 6 "liver cancer: 7.9" "Region enriched" "Detected in single" 5 "cerebral cortex: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 14 "HDLM-2: 224.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA054707 Uncertain Vesicles NA NA "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA054707: " "unprognostic (1.14e-1)" "unprognostic (2.21e-1)" "unprognostic (3.74e-2)" "unprognostic (9.43e-2)" "unprognostic (8.20e-3)" "unprognostic (5.54e-2)" "prognostic favorable (1.53e-4)" "unprognostic (3.50e-4)" "unprognostic (2.28e-1)" "unprognostic (2.30e-2)" "unprognostic (2.12e-2)" "unprognostic (4.87e-1)" "unprognostic (7.44e-4)" "unprognostic (2.77e-2)" "unprognostic (7.65e-2)" "unprognostic (2.45e-2)" "unprognostic (9.71e-2)" 0.1 0.0 0.2 0.3 0.0 0.0 0.3 0.0 1.1 0.0 0.0 0.1 0.1 0.1 0.4 0.0 0.0 0.3 0.1 0.1 0.0 13.8 39.5 0.1 0.0 0.1 0.0 0.0 1.0 0.1 0.0 0.2 0.1 0.0 0.1 0.3 0.2 0.0 0.4 0.4 0.1 0.0 0.0 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.4 0.0 0.0 0.0 0.0 224.1 0.0 0.0 0.0 0.1 0.0 0.0 3.3 0.0 0.0 0.1 0.0 0.7 2.1 0.1 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 2.5 15.8 0.0 0.0 0.0 0.3 0.0 3.5 0.0 0.0 0.1 7.4 4.2 0.1 0.7 0.4 6.7 15.7 0.0 1.0 0.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.5 0.4 1.0 0.6 0.0 0.0 0.8 0.4 0.7 7.2 0.1 1.8 0.0 0.1 0.0 0.7 19.6 11.8 0.6 0.3 0.2 3.6 0.0 0.0 0.6 8.2 1.3 0.1 0.0 3.4 0.0 0.0 0.4 22.2 0.1 0.0 0.4 0.6 0.0 0.6 0.0 0.5 0.0 0.2 3.6 0.0 0.6 0.0 0.0 1.5 1.0 21.3 0.0 0.4 6.9 0.6 0.0 0.7 0.0 0.0 0.0 0.0 2.0 1.2 0.0 0.0 0.3 0.8 1.4 0.0 0.3 2.3 CLDN4 "CPE-R, CPETR, CPETR1, hCPE-R, WBSCR8" ENSG00000189143 "Claudin 4" O14493 7 73799542-73832690 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 305.0;urinary bladder: 303.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 3149.1;Glandular and luminal cells: 2298.8;Paneth cells: 2081.0;Prostatic glandular cells: 2184.8;Urothelial cells: 8033.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "midbrain: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 358.1;BEWO: 395.0;CAPAN-2: 761.4;MCF7: 400.2;OE19: 402.0;PC-3: 495.0;RT4: 340.2;SK-BR-3: 636.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB002610 Enhanced Supported "Plasma membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "CAB002610: " "unprognostic (1.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.25e-1)" "unprognostic (1.23e-2)" "unprognostic (1.56e-2)" "unprognostic (1.84e-1)" "unprognostic (1.60e-2)" "unprognostic (7.09e-2)" "unprognostic (3.07e-1)" "prognostic unfavorable (3.28e-4)" "unprognostic (2.16e-3)" "unprognostic (5.11e-1)" "prognostic favorable (3.46e-10)" "unprognostic (5.77e-2)" "unprognostic (1.37e-1)" "unprognostic (9.38e-2)" "unprognostic (4.63e-2)" 2.6 0.4 0.1 23.0 0.0 0.2 69.0 0.8 0.3 61.2 4.8 256.3 126.9 26.7 24.4 305.0 75.8 48.9 0.4 0.2 0.0 116.2 4.8 64.0 1.0 0.4 1.5 1.2 116.2 51.9 13.1 36.3 0.3 82.2 123.3 0.3 204.6 39.1 0.5 180.8 190.6 7.3 0.0 0.7 13.3 0.6 0.2 10.7 111.7 0.3 37.5 303.5 105.7 0.0 358.1 4.4 0.0 1.5 0.0 0.4 395.0 3.3 0.2 0.3 0.4 184.9 761.4 0.6 28.0 0.1 2.6 193.3 0.0 0.5 0.4 0.7 0.4 0.2 20.3 127.0 0.1 0.1 0.9 0.0 1.9 0.1 0.4 0.3 0.0 0.2 0.3 0.7 0.0 400.2 0.7 1.9 0.7 402.0 495.0 0.5 6.9 7.6 92.4 340.2 79.5 1.7 0.4 636.8 0.8 21.6 250.9 0.9 0.5 0.9 13.7 3.1 3.5 0.9 0.7 0.7 0.6 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.3 0.2 0.0 0.4 1.5 0.3 0.0 0.2 0.0 5.1 275.7 230.2 0.0 12.2 16.2 3149.1 641.6 31.3 0.4 1255.2 548.4 0.8 287.4 954.3 218.8 0.0 771.7 18.7 1985.0 13.7 1026.1 0.0 1201.7 231.0 41.3 675.5 0.0 0.2 447.1 739.7 27.0 94.8 2298.8 27.3 0.2 0.4 0.5 76.3 0.0 0.1 1266.9 905.3 0.6 8.6 0.0 2.5 29.3 14.2 0.0 15.6 0.8 0.0 0.0 0.0 950.2 2081.0 0.0 2.5 2184.8 1906.1 21.6 635.6 0.0 0.0 0.1 68.2 0.0 0.2 1068.1 54.0 956.1 40.7 0.1 965.1 8033.4 CLEC11A "CLECSF3, LSLCL, P47, SCGF" ENSG00000105472 "C-type lectin domain containing 11A" Q9Y240 19 50723364-50725718 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 132.6" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Fibroblasts: 107.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.3" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "HEL: 363.0;HMC-1: 637.3;NB-4: 901.1;THP-1: 694.7;U-937: 358.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042690 Approved Approved Centrosome "Secreted in other tissues" NA NA 1300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Centrosome "HPA042690: AB_10795511" "unprognostic (9.33e-2)" "unprognostic (6.66e-2)" "unprognostic (2.40e-2)" "prognostic favorable (6.91e-4)" "unprognostic (2.33e-1)" "unprognostic (8.22e-2)" "unprognostic (5.52e-2)" "unprognostic (1.29e-2)" "unprognostic (5.26e-2)" "unprognostic (4.99e-2)" "unprognostic (2.79e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (1.02e-5)" "unprognostic (6.09e-2)" "unprognostic (8.66e-3)" "unprognostic (4.00e-2)" "unprognostic (1.57e-2)" 17.5 17.5 5.0 7.0 5.6 132.6 14.1 7.9 9.1 44.4 2.9 12.0 4.8 31.9 1.6 8.4 37.5 6.2 16.3 4.4 7.2 21.1 12.1 15.0 2.7 10.2 7.9 31.5 7.5 2.4 22.3 5.5 8.1 22.5 1.9 0.7 6.9 4.8 4.4 16.8 9.7 8.1 7.2 14.0 8.0 9.1 6.2 2.6 12.8 1.0 0.8 19.2 28.2 6.0 2.6 3.5 0.0 2.9 33.7 45.3 79.2 139.3 37.9 15.6 15.7 0.1 0.0 0.4 1.7 70.2 0.8 1.6 0.4 0.2 10.7 0.6 22.9 363.0 0.1 0.0 21.3 0.2 637.3 33.7 0.2 1.9 2.3 0.1 17.9 16.1 4.1 2.2 29.0 2.6 3.1 901.1 1.6 0.3 4.6 30.7 0.2 0.2 0.8 0.4 0.0 3.8 4.2 0.0 58.1 0.0 0.9 694.7 100.3 1.1 41.6 0.7 0.7 2.1 2.2 0.5 47.3 358.7 44.2 1.4 24.3 0.4 0.9 11.5 0.1 0.6 0.3 0.2 17.7 0.4 2.0 4.5 1.6 5.7 5.6 4.8 0.2 8.2 5.0 5.6 7.9 9.1 4.4 7.2 10.2 7.9 8.1 7.2 6.2 6.0 12.4 3.2 5.4 10.4 3.9 32.0 32.2 2.9 27.3 20.5 30.8 31.9 3.4 8.6 4.0 29.5 10.4 8.6 5.0 1.7 119.3 11.0 6.5 17.0 70.7 16.9 26.5 36.4 9.0 3.1 72.4 107.2 4.1 14.1 5.7 18.9 51.4 6.3 49.4 21.9 8.3 4.5 10.2 21.5 73.3 19.9 70.8 29.6 78.2 9.4 11.2 70.4 14.4 8.0 12.9 3.1 1.7 67.4 0.9 21.4 0.5 13.7 5.0 20.7 65.7 20.2 59.2 17.2 21.7 26.3 45.9 18.3 5.8 56.7 3.5 17.8 CLEC1A "CLEC1, MGC34328" ENSG00000150048 "C-type lectin domain family 1 member A" Q8NC01 12 10069554-10111627 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 50.2;placenta: 49.0" "Cell type enhanced" "Detected in some" "Adipocytes: 51.4;Cytotrophoblasts: 51.5;Endothelial cells: 38.1;Extravillous trophoblasts: 61.7;Syncytiotrophoblasts: 52.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 21.3;HUVEC TERT2: 18.3;SuSa: 5.6;U-266/70: 4.9;U-266/84: 11.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (7.63e-2)" "unprognostic (2.51e-2)" "unprognostic (5.96e-2)" "unprognostic (2.02e-2)" "unprognostic (1.09e-1)" "unprognostic (1.16e-2)" "unprognostic (1.37e-1)" "unprognostic (1.03e-1)" "unprognostic (7.15e-2)" "unprognostic (2.73e-2)" "unprognostic (3.26e-2)" "unprognostic (1.81e-1)" "unprognostic (3.35e-3)" "unprognostic (3.94e-2)" "unprognostic (1.28e-1)" "unprognostic (1.20e-1)" "unprognostic (2.02e-2)" 16.2 3.2 4.4 4.1 4.2 0.4 14.8 6.6 5.6 11.4 4.1 4.3 1.5 6.8 2.7 3.8 9.2 5.7 9.0 3.9 3.8 5.8 2.9 29.8 5.9 4.8 4.5 5.4 2.3 1.6 3.7 49.0 4.7 6.3 2.0 0.6 2.9 2.4 3.9 4.1 4.4 8.7 4.3 8.0 3.7 2.1 5.1 50.2 7.6 4.4 3.5 6.1 8.6 4.1 0.0 0.0 0.3 0.3 0.2 0.2 21.3 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.4 1.2 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.1 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 18.3 0.0 0.0 1.9 0.0 0.0 0.0 0.4 3.0 0.0 0.4 0.0 0.0 0.1 0.1 0.2 0.4 0.0 0.3 0.3 0.0 5.6 0.0 0.0 1.4 0.0 0.2 0.2 0.0 4.9 11.5 0.0 0.2 0.1 0.0 0.1 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.2 4.4 4.2 6.6 5.6 3.9 3.8 4.8 4.5 4.7 4.3 5.1 4.1 51.4 0.0 0.5 0.0 0.5 2.2 0.1 0.0 1.2 0.0 0.3 0.1 1.3 0.0 0.0 0.0 0.0 51.5 0.2 0.0 0.0 0.0 0.4 0.0 0.1 38.1 0.0 0.0 0.0 0.0 61.7 1.2 0.0 0.0 0.0 0.0 16.8 0.2 5.0 0.0 0.0 0.0 0.0 4.7 14.1 0.6 7.5 4.0 3.6 11.2 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.9 4.0 2.9 0.3 1.6 52.1 0.6 0.3 0.0 0.5 CLEC1B CLEC2 ENSG00000165682 "C-type lectin domain family 1 member B" Q9P126 12 9985642-10013424 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "liver: 65.3" "Cell type enriched" "Detected in some" 8 "Hepatic stellate cells: 535.8" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 13.8" "Group enriched" "Detected in many" 4 "granulocytes: 13.8;monocytes: 5.0" "Group enriched" "Detected in some" 6 "Karpas-707: 11.3;U-266/84: 28.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA051108 Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 16: U-266 - Nucleosome" "Cluster 51: Myeloid cells - Hemostasis" "HPA051108: " "unprognostic (2.03e-1)" "unprognostic (2.59e-2)" "unprognostic (1.45e-1)" "unprognostic (4.63e-3)" "unprognostic (1.51e-1)" "unprognostic (1.15e-3)" "unprognostic (1.26e-2)" "unprognostic (7.71e-2)" "unprognostic (4.98e-2)" "unprognostic (1.58e-1)" "unprognostic (8.13e-2)" "unprognostic (1.49e-3)" "unprognostic (1.46e-2)" "unprognostic (1.27e-1)" "unprognostic (2.11e-1)" "unprognostic (2.91e-2)" 0.1 0.4 0.1 0.9 0.2 9.2 0.0 0.2 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.4 0.2 0.0 0.3 0.1 65.3 2.2 0.7 0.3 0.2 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.1 0.0 0.0 2.9 0.2 2.2 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 2.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 3.3 0.0 13.8 5.0 7.5 0.0 4.4 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 3.3 0.1 4.1 1.2 0.0 13.8 0.1 0.2 0.2 0.2 0.0 0.3 0.3 0.2 0.4 0.0 0.6 0.4 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 7.4 0.0 53.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 535.8 5.0 0.1 0.0 0.0 0.0 0.0 49.9 0.0 0.3 0.0 64.6 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.6 0.0 0.0 0.0 1.1 0.6 0.0 0.0 CLIC6 "CLIC1L, CLIC5" ENSG00000159212 "Chloride intracellular channel 6" Q96NY7 21 34668994-34718227 "Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "choroid plexus: 235.9;stomach 1: 138.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 30.0;Club cells: 41.6;Gastric mucus-secreting cells: 26.5;Respiratory ciliated cells: 81.1;Skeletal myocytes: 24.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 2.6;NTERA-2: 3.6;T-47d: 7.3;THP-1: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065285 Enhanced NA NA 180000 "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "HPA065285: AB_2685454" "prognostic favorable (6.11e-5)" "unprognostic (2.17e-2)" "unprognostic (1.65e-2)" "unprognostic (4.27e-2)" "unprognostic (2.93e-2)" "unprognostic (2.67e-2)" "unprognostic (2.78e-2)" "prognostic favorable (3.15e-5)" "unprognostic (4.90e-3)" "unprognostic (1.53e-1)" "unprognostic (5.52e-2)" "unprognostic (3.26e-2)" "unprognostic (1.66e-2)" "unprognostic (1.16e-2)" "unprognostic (3.48e-1)" "unprognostic (1.99e-1)" "unprognostic (1.43e-3)" 11.4 0.1 1.2 4.3 0.7 0.1 11.9 2.4 1.0 15.8 235.9 4.0 2.0 2.1 2.7 2.6 11.4 8.8 11.1 11.3 0.7 2.6 0.9 9.8 1.2 3.0 4.5 4.9 3.2 28.3 3.3 0.1 2.6 9.8 2.9 0.2 25.4 7.0 1.6 6.0 3.1 0.7 1.3 1.0 138.5 0.3 4.4 8.4 13.2 4.3 3.8 12.9 5.3 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.6 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.6 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.9 7.3 3.4 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.7 2.4 1.0 11.3 0.7 3.0 4.5 2.6 1.3 4.4 0.7 0.3 6.4 20.7 1.3 0.0 0.6 5.1 7.3 4.0 0.0 15.6 11.0 11.4 30.0 41.6 9.2 0.0 0.0 0.2 2.2 1.9 8.0 0.1 15.1 0.3 0.4 4.9 0.0 0.3 0.9 0.0 3.7 26.5 2.2 1.3 11.8 0.0 0.0 0.1 0.0 0.6 1.4 16.2 0.0 0.4 0.3 0.3 0.4 7.2 0.0 0.6 0.0 0.0 0.0 0.1 17.2 0.6 3.0 0.4 10.2 0.1 0.2 81.1 0.0 0.0 24.0 2.4 0.2 0.2 0.6 0.4 0.0 0.4 0.0 2.8 20.4 CLIP3 "CLIPR-59, RSNL1" ENSG00000105270 "CAP-Gly domain containing linker protein 3" Q96DZ5 19 36014660-36033343 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 158.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 30.9;Excitatory neurons: 24.8;Granulosa cells: 25.7;Horizontal cells: 42.1;Inhibitory neurons: 30.7;Muller glia cells: 26.9;Peritubular cells: 24.5" "Cancer enhanced" "Detected in all" "glioma: 65.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 83.3;fHDF/TERT166: 61.5;HSkMC: 93.1;hTERT-RPE1: 80.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079430 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "HPA079430: " "unprognostic (1.91e-2)" "unprognostic (8.70e-2)" "unprognostic (1.16e-2)" "unprognostic (5.01e-2)" "unprognostic (1.19e-1)" "unprognostic (1.38e-1)" "unprognostic (3.60e-2)" "unprognostic (2.92e-2)" "unprognostic (2.55e-2)" "unprognostic (3.26e-2)" "prognostic favorable (2.80e-4)" "unprognostic (9.44e-2)" "prognostic unfavorable (1.56e-10)" "unprognostic (6.31e-3)" "unprognostic (1.52e-1)" "unprognostic (9.63e-2)" "unprognostic (1.09e-2)" 16.4 13.5 109.8 9.7 117.0 0.5 14.0 92.0 142.5 50.9 0.3 75.3 6.5 66.2 12.7 16.3 35.7 23.5 12.7 122.5 121.5 11.5 2.9 10.0 7.0 105.2 158.4 48.6 3.6 2.6 46.9 9.3 140.0 29.2 8.6 54.9 6.3 33.4 3.4 7.8 21.4 37.9 60.3 9.9 25.7 12.0 92.6 9.4 5.5 3.5 6.2 68.2 32.4 106.2 1.3 3.8 33.0 1.4 53.8 83.3 1.1 19.1 45.9 15.6 23.4 4.0 1.3 1.8 7.6 61.5 1.3 1.6 0.6 0.2 11.1 2.4 1.3 1.0 4.1 0.8 54.1 1.0 1.0 93.1 0.9 13.4 0.3 80.8 17.7 13.0 1.9 3.5 35.2 2.9 18.6 1.3 4.0 1.3 0.9 2.4 0.6 1.1 0.5 1.2 32.2 37.6 2.2 0.8 1.0 13.5 1.2 0.4 4.9 26.8 21.9 1.3 1.2 2.8 2.5 1.4 41.1 1.8 10.2 0.0 0.1 0.3 0.2 0.2 0.0 0.2 0.3 0.1 0.0 0.1 0.3 0.2 0.1 0.4 0.0 0.1 0.2 0.1 109.8 117.0 92.0 142.5 122.5 121.5 105.2 158.4 140.0 60.3 92.6 106.2 1.1 0.0 0.0 11.4 0.1 0.6 0.6 0.5 0.6 30.9 0.4 4.3 4.3 0.0 0.1 1.8 2.1 0.6 0.0 0.3 0.0 0.1 11.3 0.7 15.3 3.6 2.4 0.0 24.8 0.2 0.5 16.1 1.1 0.7 0.0 25.7 5.0 0.2 0.8 42.1 30.7 0.9 0.0 0.3 2.3 19.2 22.1 0.5 3.6 10.3 0.0 26.9 0.0 14.6 15.3 0.3 0.0 24.5 0.2 0.4 0.3 0.3 0.7 13.7 6.6 8.7 12.8 2.3 3.5 0.5 1.3 1.2 0.6 2.9 0.2 0.1 CLRN3 "MGC32871, TMEM12, USH3AL1" ENSG00000180745 "Clarin 3" Q8NCR9 10 127877841-127892941 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 89.0;kidney: 43.9;liver: 79.9" "Group enriched" "Detected in some" 5 "Distal enterocytes: 102.0;Enteroendocrine cells: 41.5;Hepatocytes: 43.0;Intestinal goblet cells: 75.3;Paneth cells: 95.9;Proximal enterocytes: 155.4;Proximal tubular cells: 68.3;Undifferentiated cells: 45.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 45.3;renal cancer: 30.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 41 "OE19: 96.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA014482 Approved NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "HPA014482: AB_2082885" "unprognostic (7.34e-3)" "unprognostic (1.55e-1)" "unprognostic (1.41e-2)" "unprognostic (1.46e-3)" "unprognostic (1.22e-2)" "unprognostic (1.06e-1)" "unprognostic (5.08e-2)" "unprognostic (2.62e-1)" "unprognostic (6.22e-2)" "unprognostic (4.67e-1)" "unprognostic (8.86e-2)" "prognostic favorable (8.98e-4)" "unprognostic (1.74e-1)" "unprognostic (2.89e-3)" "unprognostic (3.00e-2)" 0.6 0.1 0.4 5.6 0.4 0.0 0.3 0.3 0.5 0.0 0.3 71.1 73.4 0.1 0.0 0.0 0.0 15.2 0.0 0.4 0.3 43.9 79.9 0.0 0.1 0.3 0.3 0.0 0.3 0.0 0.2 0.0 0.4 0.0 70.3 0.0 0.0 0.2 0.0 0.0 89.0 1.7 0.3 0.1 1.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 96.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.4 0.3 0.5 0.4 0.3 0.3 0.3 0.4 0.3 0.4 0.4 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 102.0 15.6 0.4 0.0 0.2 0.0 0.1 41.5 0.0 0.4 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.4 43.0 0.0 0.0 0.1 75.3 0.0 0.6 0.0 0.0 0.0 0.5 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.5 95.9 0.0 0.0 0.0 155.4 68.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 45.6 0.0 CLU "APOJ, CLI, CLU1, CLU2, KUB1, SGP-2, SP-40, TRPM-2" ENSG00000120885 Clusterin P10909 8 27596917-27614700 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Complement pathway, Immunity, Innate immunity" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 10230.8;liver: 9779.1" "Group enriched" "Detected in all" 4 "Cholangiocytes: 2586.5;Collecting duct cells: 3525.7;Hepatocytes: 4230.2;Muller glia cells: 8522.6" "Cancer enhanced" "Detected in all" "glioma: 1485.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "basophil: 767.1" "Lineage enriched" "Detected in all" 33 "granulocytes: 767.1" "Cell line enhanced" "Detected in all" "HeLa: 3644.3;SK-BR-3: 3500.4;T-47d: 2562.4;U-2 OS: 2225.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000572, CAB016253, HPA075983" Enhanced Supported Cytosol "Secreted to blood" NA NA 169000000000 29000000000 "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" Cytosol "CAB016253: AB_673562, HPA000572: AB_1078539, HPA075983: " "unprognostic (1.10e-2)" "unprognostic (1.81e-2)" "unprognostic (1.14e-3)" "unprognostic (2.74e-2)" "unprognostic (5.59e-2)" "unprognostic (4.13e-2)" "unprognostic (1.76e-2)" "unprognostic (2.37e-1)" "unprognostic (1.46e-1)" "unprognostic (1.05e-1)" "unprognostic (2.87e-2)" "unprognostic (1.41e-1)" "unprognostic (1.80e-2)" "unprognostic (2.33e-2)" "unprognostic (1.72e-1)" "prognostic favorable (7.66e-5)" "unprognostic (5.29e-2)" 1438.7 3809.7 6730.2 897.0 6536.5 53.2 1423.8 6992.3 8050.5 1389.4 6057.7 1407.9 323.9 1152.5 9148.8 768.6 3543.7 2863.5 617.7 6660.5 8149.9 1170.5 9779.1 827.8 2309.4 10230.8 8450.9 756.7 2246.3 1689.2 827.2 131.2 8001.8 986.4 276.1 3274.6 1453.0 5466.4 114.1 281.9 662.7 1439.9 8813.6 295.4 1081.6 2709.4 7385.0 388.1 2406.8 267.7 2343.1 1777.4 741.0 9752.3 13.0 1673.1 73.2 86.4 401.4 546.1 230.7 297.8 584.8 77.3 40.1 323.4 265.5 6.6 1159.9 267.1 926.6 561.2 318.4 48.1 50.3 1268.7 306.4 741.8 3644.3 403.7 348.8 19.2 1891.2 923.4 189.1 334.0 95.5 719.5 1028.1 10.6 10.1 842.2 27.5 288.4 5.7 56.5 603.3 505.3 197.6 6.5 276.1 236.3 763.0 1220.2 66.7 41.7 412.3 3500.4 18.1 349.1 2562.4 10.3 153.2 24.0 2225.3 131.8 101.9 108.1 419.0 16.1 1808.8 122.4 10.3 767.1 18.4 8.9 19.8 6.2 7.4 0.7 23.1 21.3 6.2 1.6 2.8 7.0 79.8 9.3 1.1 11.8 6.5 1073.6 6730.2 6536.5 6992.3 8050.5 6660.5 8149.9 10230.8 8450.9 8001.8 8813.6 7385.0 9752.3 255.3 32.1 91.8 720.5 16.1 81.3 944.6 134.1 118.9 74.3 475.3 480.4 86.1 2586.5 514.0 3525.7 77.2 116.3 15.2 23.6 41.1 488.3 311.3 196.9 31.1 442.0 9.5 92.4 73.4 620.7 22.7 614.8 226.8 185.6 803.0 31.4 1037.7 4230.2 12.6 30.3 81.0 30.9 28.5 180.5 88.9 789.3 114.3 244.6 206.3 69.3 25.1 8522.6 11.3 61.3 54.3 174.8 15.0 57.2 11.6 200.5 9.9 459.2 709.1 221.4 13.1 334.4 157.7 189.8 20.3 58.8 55.3 85.6 58.7 288.9 49.3 353.7 CNTN1 "F3, GP135" ENSG00000018236 "Contactin 1" Q12860 12 40692439-41072415 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 158.2" "Group enriched" "Detected in many" 5 "Astrocytes: 763.9;Excitatory neurons: 844.8;Inhibitory neurons: 699.0;Oligodendrocyte precursor cells: 1021.4" "Cancer enhanced" "Detected in many" "glioma: 17.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A549: 224.4;HaCaT: 40.3;SCLC-21H: 68.5;SH-SY5Y: 40.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025200, HPA070467" Enhanced Approved "Intracellular and membrane" NA NA 450000000 "Cluster 17: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB025200: , HPA070467: AB_2732156" "unprognostic (3.18e-2)" "unprognostic (5.96e-3)" "unprognostic (3.66e-2)" "unprognostic (7.34e-2)" "unprognostic (2.00e-1)" "unprognostic (2.00e-1)" "unprognostic (1.54e-1)" "unprognostic (2.05e-1)" "unprognostic (9.13e-2)" "unprognostic (1.08e-1)" "unprognostic (1.72e-2)" "unprognostic (1.86e-1)" "unprognostic (1.32e-2)" "unprognostic (8.15e-4)" "unprognostic (6.98e-2)" "unprognostic (5.46e-2)" "prognostic unfavorable (3.75e-4)" 3.9 33.2 64.0 2.5 75.3 0.2 8.8 119.4 84.2 14.1 0.0 3.1 1.7 11.5 2.6 9.1 2.2 11.7 0.8 93.6 59.8 12.4 1.2 4.4 4.5 72.6 94.7 49.2 6.0 1.4 10.4 0.3 70.0 27.8 3.8 26.8 5.4 27.7 0.8 12.8 3.0 10.6 129.0 8.2 5.0 9.4 79.2 1.0 1.2 1.6 3.9 21.5 6.6 158.2 0.1 224.4 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.3 0.3 0.1 0.1 0.0 0.0 40.3 6.0 11.2 0.0 0.2 2.4 0.0 0.7 0.0 0.0 0.0 0.7 0.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.4 0.0 0.2 1.5 0.2 0.1 0.0 1.0 0.3 0.0 0.0 68.5 40.3 0.1 2.5 2.7 1.0 0.1 0.6 0.0 0.1 4.3 0.1 10.0 2.8 0.1 0.0 0.3 0.0 0.9 2.6 0.5 0.7 0.3 0.2 0.3 0.4 0.2 0.2 0.1 0.4 0.4 0.2 1.2 0.7 0.4 0.9 0.2 0.0 64.0 75.3 119.4 84.2 93.6 59.8 72.6 94.7 70.0 129.0 79.2 158.2 0.3 0.0 5.9 763.9 0.1 5.2 1.1 1.6 4.0 32.1 0.4 1.8 0.7 0.0 4.5 5.5 29.2 0.0 0.0 0.0 1.9 0.0 34.9 4.3 7.1 0.7 0.0 0.0 844.8 0.0 0.0 13.3 0.0 0.3 0.0 5.0 0.0 0.0 0.1 11.8 699.0 0.0 2.0 0.0 4.0 149.5 62.7 0.1 10.6 54.4 0.0 34.6 0.0 1021.4 23.9 0.7 0.0 60.2 0.0 0.3 0.0 0.0 0.4 5.9 0.0 0.5 3.6 0.6 0.8 2.1 13.5 0.0 0.5 0.3 0.0 0.2 CNTNAP2 "Caspr2, KIAA0868, NRXN4" ENSG00000174469 "Contactin associated protein 2" Q9UHC6 7 146116002-148420998 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Autism, Autism spectrum disorder, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 20.7;retina: 14.4" "Group enriched" "Detected in many" 4 "Excitatory neurons: 3383.0;Inhibitory neurons: 6845.7" "Cancer enhanced" "Detected in many" "prostate cancer: 10.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.5" "Lineage enriched" "Detected in single" 25 "B-cells: 2.5" "Cell line enhanced" "Detected in some" "AF22: 8.0;CACO-2: 6.7;NTERA-2: 12.0;SCLC-21H: 21.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002739 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA002739: AB_1078545" "unprognostic (2.49e-2)" "unprognostic (1.49e-2)" "unprognostic (4.05e-1)" "unprognostic (3.08e-3)" "unprognostic (1.77e-1)" "unprognostic (2.29e-1)" "unprognostic (2.51e-2)" "unprognostic (1.45e-2)" "unprognostic (1.18e-1)" "unprognostic (2.19e-1)" "unprognostic (3.67e-2)" "unprognostic (2.68e-1)" "unprognostic (1.41e-1)" "unprognostic (1.78e-1)" "unprognostic (1.37e-1)" "unprognostic (2.33e-1)" "unprognostic (1.00e-3)" 0.2 0.8 10.0 0.2 13.8 0.0 0.6 1.4 20.7 0.1 0.0 0.8 0.0 0.0 0.0 0.4 0.6 0.0 0.2 5.6 5.7 0.1 1.9 0.0 0.4 5.7 0.5 1.1 0.2 0.3 3.8 0.5 3.8 4.1 0.4 14.4 0.1 0.1 0.0 0.0 0.9 0.0 0.0 0.4 0.2 0.5 1.8 3.7 0.3 0.0 0.2 0.1 0.1 0.0 0.0 0.0 8.0 3.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 6.7 0.1 0.0 0.0 0.2 0.0 2.0 1.7 0.6 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 12.0 1.4 0.0 0.0 0.0 2.2 0.0 0.0 21.5 1.4 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 10.0 13.8 1.4 20.7 5.6 5.7 5.7 0.5 3.8 0.0 1.8 0.0 0.1 0.0 0.0 65.6 9.3 0.1 0.3 15.5 1.8 33.9 0.3 0.0 1.2 7.2 4.1 0.0 2.1 40.8 0.0 1.8 0.0 1.4 7.2 0.6 0.0 0.6 2.4 0.0 3383.0 0.7 6.8 1.1 0.5 0.7 0.0 0.2 0.0 8.9 3.3 1031.4 6845.7 3.9 0.0 0.6 2.0 2.7 1.2 0.4 0.0 180.8 0.2 8.2 1.0 429.3 914.7 4.1 2.1 0.0 0.3 7.4 4.7 0.5 0.9 16.7 0.0 0.0 0.9 2.4 12.0 9.1 0.0 6.3 0.0 1.2 6.8 0.2 COL12A1 COL12A1L ENSG00000111799 "Collagen type XII alpha 1 chain" Q99715 6 75084326-75206267 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Endometrial stromal cells: 44.3;Excitatory neurons: 52.9;Fibroblasts: 99.7;Leydig cells: 60.3;Sertoli cells: 46.0;Smooth muscle cells: 48.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "fHDF/TERT166: 1432.1;SiHa: 846.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 29.1" "HPA009143, HPA010021" Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA 9100000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Cytosol "HPA009143: AB_1847095, HPA010021: " "unprognostic (2.60e-2)" "unprognostic (2.80e-3)" "unprognostic (7.92e-2)" "unprognostic (8.27e-3)" "unprognostic (1.13e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (3.47e-3)" "unprognostic (1.38e-1)" "unprognostic (4.30e-1)" "unprognostic (1.18e-3)" "unprognostic (3.04e-1)" "prognostic unfavorable (1.69e-9)" "unprognostic (1.03e-3)" "unprognostic (1.81e-1)" "unprognostic (3.16e-3)" "unprognostic (1.92e-2)" 105.1 15.7 2.2 16.0 1.9 0.0 65.4 0.8 2.7 112.8 0.4 74.9 8.7 124.5 5.5 36.2 42.2 20.9 25.5 1.0 1.2 25.9 3.5 24.6 7.2 1.8 4.8 123.2 5.9 5.0 4.8 1.8 0.6 20.8 17.2 0.4 16.1 42.4 14.4 48.9 40.6 72.1 0.6 11.4 18.1 4.6 2.0 5.5 19.3 12.5 4.2 26.3 45.8 0.8 0.2 2.2 11.5 0.2 270.2 162.0 28.3 275.4 229.3 186.2 257.3 27.5 0.7 0.0 27.7 1432.1 3.9 59.2 0.5 28.7 174.6 0.2 1.4 0.2 101.1 0.1 97.9 0.3 0.2 234.9 5.0 42.2 50.6 173.6 32.0 0.1 0.0 0.0 29.4 0.2 0.1 0.2 6.4 0.0 15.3 0.1 23.1 0.2 8.9 14.4 0.0 0.0 846.1 21.2 0.3 15.5 131.8 0.5 0.2 78.5 97.0 41.5 91.4 0.1 0.1 0.4 26.4 0.3 40.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.9 0.8 2.7 1.0 1.2 1.8 4.8 0.6 0.6 2.0 0.8 14.2 76.9 5.1 2.3 0.0 20.6 0.6 12.7 5.2 0.4 4.7 7.1 4.1 0.0 4.7 3.7 0.0 0.6 0.0 0.0 0.0 1.4 24.1 6.3 44.3 11.0 0.0 0.0 52.9 4.6 1.3 99.7 2.6 14.1 1.3 0.1 3.3 0.0 0.8 0.0 32.4 0.0 0.0 0.3 18.4 14.7 60.3 1.8 21.4 38.4 0.0 0.0 0.0 19.6 1.2 6.7 0.0 13.2 0.1 1.7 0.0 0.9 1.7 0.0 46.0 20.0 48.6 0.3 0.6 0.6 13.1 0.7 2.5 1.4 0.1 0.3 COL14A1 UND ENSG00000187955 "Collagen type XIV alpha 1 chain" Q05707 8 120059780-120373573 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 205.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1;Endometrial stromal cells: 97.0;Fibroblasts: 235.9;Smooth muscle cells: 118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 54.4;hTERT-RPE1: 29.7;RH-30: 123.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA023781 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA 3200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA023781: AB_1847098" "unprognostic (1.10e-1)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-3)" "unprognostic (5.96e-2)" "unprognostic (4.29e-2)" "unprognostic (7.61e-2)" "unprognostic (3.77e-2)" "unprognostic (4.36e-1)" "unprognostic (5.07e-2)" "prognostic unfavorable (5.79e-5)" "unprognostic (1.07e-2)" "unprognostic (8.21e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.01e-4)" 69.0 16.2 1.6 42.2 1.9 0.3 58.8 1.5 2.4 205.8 2.9 39.8 7.7 78.2 35.2 50.2 46.2 142.2 45.4 1.5 2.0 32.1 19.5 27.7 12.8 3.4 2.2 83.2 15.7 6.0 4.0 152.7 2.7 43.8 53.9 0.6 13.5 24.9 7.0 13.3 35.3 147.6 3.1 28.4 25.6 5.5 2.4 5.3 43.2 36.1 16.5 108.5 93.0 3.0 0.0 0.0 0.9 0.0 5.4 54.4 0.1 0.1 6.7 0.2 0.1 0.0 0.0 0.6 1.8 8.2 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 1.8 0.0 13.2 0.2 0.2 14.4 0.3 2.6 0.0 29.7 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.4 4.2 0.0 0.0 0.0 123.4 0.2 4.8 0.0 0.5 0.2 0.1 0.1 0.1 3.2 0.0 0.1 0.0 1.3 0.3 0.2 2.9 0.4 0.0 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.9 1.5 2.4 1.5 2.0 3.4 2.2 2.7 3.1 2.4 3.0 8.0 0.0 1.1 0.0 0.1 11.3 0.4 2.1 75.1 0.1 1.8 25.3 13.2 0.0 4.3 1.8 0.0 34.4 0.3 0.0 0.0 0.0 1.0 6.9 97.0 7.8 0.0 0.0 5.6 0.0 4.0 235.9 6.1 11.3 3.8 0.2 18.5 0.0 6.2 0.0 5.2 0.0 0.0 0.0 18.5 1.4 14.6 1.7 5.4 5.6 0.0 0.1 0.0 1.0 3.3 0.0 0.0 15.4 0.5 0.6 0.0 0.0 0.1 0.5 0.0 4.2 118.2 4.4 2.8 3.9 9.7 25.3 2.7 4.5 0.0 0.3 COL21A1 ENSG00000124749 "Collagen type XXI alpha 1 chain" Q96P44 6 56056590-56394094 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 24.1;placenta: 28.3" "Cell type enhanced" "Detected in many" "Astrocytes: 66.6;Cardiomyocytes: 36.9;Extravillous trophoblasts: 75.3;Inhibitory neurons: 63.3;Respiratory ciliated cells: 51.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ASC TERT1: 23.4;BEWO: 7.6;HSkMC: 24.0;SuSa: 11.1" "Low region specificity" "Detected in all" HPA031212 Supported Cytosol "Secreted to extracellular matrix" NA NA 290000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "HPA031212: AB_10599941" "unprognostic (1.69e-1)" "unprognostic (4.53e-2)" "unprognostic (1.58e-1)" "unprognostic (2.56e-1)" "unprognostic (1.21e-1)" "unprognostic (9.32e-3)" "unprognostic (6.84e-2)" "unprognostic (9.04e-3)" "unprognostic (1.54e-3)" "unprognostic (2.17e-1)" "unprognostic (5.29e-2)" "unprognostic (3.10e-1)" "unprognostic (1.26e-3)" "unprognostic (3.27e-2)" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (1.27e-3)" 2.6 1.4 2.6 0.6 3.2 0.0 1.4 3.3 1.9 24.1 11.4 7.8 0.5 12.4 2.8 2.4 7.4 3.8 4.2 2.4 5.6 1.1 1.2 7.6 0.5 2.7 6.3 3.7 1.9 0.6 1.9 28.3 3.1 3.5 2.0 0.0 5.0 10.7 1.3 6.6 1.3 7.9 1.5 0.5 2.7 2.7 4.0 0.7 1.0 6.6 0.5 6.1 6.0 2.7 0.0 3.4 0.2 0.0 1.3 23.4 7.6 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.2 0.1 0.0 24.0 0.9 0.0 0.3 0.5 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 11.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.2 3.3 1.9 2.4 5.6 2.7 6.3 3.1 1.5 4.0 2.7 6.4 0.0 1.5 66.6 0.0 5.9 2.2 2.8 2.2 0.0 0.3 0.4 36.9 0.0 8.2 0.0 0.0 27.5 0.1 0.0 0.0 0.0 7.4 24.8 10.6 6.6 0.0 0.0 16.0 0.0 75.3 28.2 0.5 1.2 0.0 0.2 2.9 0.0 6.1 0.0 63.3 0.0 16.2 0.3 3.0 1.7 15.2 0.3 5.4 0.0 0.0 0.0 0.0 3.5 1.6 0.0 0.0 12.4 0.0 0.1 0.1 0.1 51.3 0.0 0.0 7.3 15.0 1.2 2.5 1.0 4.1 23.3 0.4 2.1 0.2 1.3 COL26A1 "EMI6, EMID2, Emu2" ENSG00000160963 "Collagen type XXVI alpha 1 chain" Q96A83 7 101362875-101559024 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.8;liver: 5.5" "Group enriched" "Detected in some" 7 "Excitatory neurons: 68.4;Inhibitory neurons: 18.5" "Group enriched" "Detected in many" 6 "endometrial cancer: 12.6;ovarian cancer: 5.7;prostate cancer: 4.6;testis cancer: 14.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 45 "plasmacytoid DC: 9.2" "Lineage enriched" "Detected in single" 45 "dendritic cells: 9.2" "Cell line enhanced" "Detected in some" "AF22: 30.0;BEWO: 23.9;HAP1: 10.7;NTERA-2: 25.4;SuSa: 19.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA027059 Approved Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA027059: AB_1848142" "unprognostic (5.94e-3)" "unprognostic (2.16e-2)" "unprognostic (2.19e-2)" "unprognostic (4.67e-2)" "unprognostic (1.66e-1)" "unprognostic (3.35e-1)" "prognostic favorable (2.32e-5)" "unprognostic (1.48e-1)" "unprognostic (1.16e-1)" "unprognostic (2.85e-2)" "unprognostic (1.26e-3)" "unprognostic (1.78e-1)" "unprognostic (4.24e-3)" "unprognostic (3.60e-1)" "unprognostic (1.50e-1)" "unprognostic (7.48e-4)" "unprognostic (2.83e-3)" 0.1 4.4 5.2 0.1 7.4 0.2 0.1 0.2 12.8 0.2 0.2 0.0 0.0 0.3 0.1 0.0 0.3 0.1 0.0 9.8 1.2 4.9 5.5 0.4 0.5 1.1 0.9 0.4 2.2 3.9 0.9 0.3 0.9 2.2 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.4 0.2 0.3 1.0 2.0 1.2 0.1 0.0 0.1 0.2 0.1 4.2 0.0 0.8 30.0 1.9 0.0 0.0 23.9 0.0 0.0 0.0 0.0 1.3 0.0 0.1 4.7 0.0 0.1 0.0 10.7 0.0 0.0 1.0 1.3 0.0 0.0 7.9 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 25.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.6 0.0 0.0 0.2 19.2 0.3 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 5.2 7.4 0.2 12.8 9.8 1.2 1.1 0.9 0.9 0.4 2.0 4.2 0.0 0.0 0.0 3.3 0.7 0.0 0.3 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.0 5.5 0.0 0.3 0.0 0.0 0.0 0.2 1.5 0.1 1.7 0.1 0.0 0.0 68.4 0.6 0.4 0.5 0.0 0.2 0.0 1.0 0.0 3.6 0.1 0.0 18.5 0.0 0.0 0.0 0.0 3.5 0.0 0.5 0.0 5.6 0.0 0.0 0.0 3.5 2.1 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 2.0 0.0 0.0 0.4 0.0 0.9 0.0 0.4 COL3A1 EDS4A ENSG00000168542 "Collagen type III alpha 1 chain" P02461 2 188974373-189012746 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aortic aneurysm, Disease variant, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 2369.0;gallbladder: 2092.8;placenta: 1981.7;smooth muscle: 2140.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 2812.0;Fibroblasts: 1764.2;Smooth muscle cells: 643.0;Theca cells: 466.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 4 "cerebral cortex: 15.0;thalamus: 10.9;white matter: 4.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 1362.4;ASC diff: 2465.0;ASC TERT1: 4252.6;fHDF/TERT166: 1815.7;HHSteC: 1690.0;HSkMC: 3189.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 61.1" "HPA007583, CAB016766, CAB059993" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 32000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB016766: , CAB059993: AB_2314211, HPA007583: AB_1078548" "unprognostic (1.12e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (6.01e-2)" "unprognostic (2.78e-1)" "unprognostic (2.04e-1)" "unprognostic (6.94e-2)" "unprognostic (6.77e-3)" "unprognostic (3.57e-3)" "unprognostic (2.60e-2)" "unprognostic (1.89e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (3.59e-10)" "unprognostic (1.70e-3)" "unprognostic (3.76e-2)" "unprognostic (7.61e-2)" "unprognostic (6.17e-3)" 763.6 48.9 1.1 575.5 2.3 1.1 340.0 1.4 15.0 2369.0 11.5 275.9 84.5 768.9 60.9 298.5 177.6 2092.8 234.6 1.3 1.4 42.9 97.4 187.0 119.0 1.8 2.0 146.9 45.2 37.0 13.6 1981.7 2.2 147.5 334.7 0.0 65.6 276.9 67.1 329.8 152.5 2140.7 1.9 134.7 156.9 63.5 10.9 40.9 71.8 71.8 73.1 1097.6 273.8 4.6 0.0 0.2 1362.4 53.0 2465.0 4252.6 0.9 558.6 495.3 239.4 212.8 8.1 0.0 0.6 0.3 1815.7 0.1 0.8 1.1 1.0 26.4 0.0 0.9 0.7 228.9 0.2 1690.0 2.0 0.6 3189.5 0.0 291.5 46.9 1.0 12.5 0.0 0.4 0.0 146.4 0.0 0.2 1.4 2.6 0.1 1.7 0.3 38.5 0.5 0.0 7.2 1.3 21.1 14.5 0.4 0.0 954.8 0.1 0.0 0.7 2.3 28.0 117.3 0.5 2.8 1.3 0.4 0.5 1.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.3 1.4 15.0 1.3 1.4 1.8 2.0 2.2 1.9 10.9 4.6 111.8 3.2 13.7 0.0 0.6 171.6 0.4 1.9 3.4 0.0 7.7 9.9 11.1 0.0 1.3 0.0 0.0 57.9 1.6 0.0 0.0 2.4 29.0 75.4 2812.0 68.4 6.0 0.0 0.0 0.0 58.1 1764.2 4.1 60.7 6.3 9.7 235.2 0.9 91.1 0.0 0.2 0.0 0.0 0.6 275.3 20.8 323.1 17.5 172.5 20.6 0.0 0.0 0.0 0.0 0.0 3.7 0.0 235.9 1.5 0.6 0.0 0.2 1.6 0.0 453.6 224.3 643.0 0.9 1.5 2.2 155.7 126.3 29.1 466.8 0.0 0.4 COL6A1 ENSG00000142156 "Collagen type VI alpha 1 chain" P12109 21 45981769-46005050 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 796.8" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 578.3;Fibroblasts: 816.1;Leydig cells: 353.0;Peritubular cells: 251.3;Smooth muscle cells: 324.4;Theca cells: 246.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1157.2;ASC TERT1: 2331.5;BJ: 927.1;HHSteC: 1025.3;HSkMC: 1711.4;U-138 MG: 1297.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 46.8" "HPA019142, HPA029401" Enhanced Approved Cytosol "Secreted to extracellular matrix" NA NA 250000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "HPA019142: AB_1847093, HPA029401: AB_10601361" "unprognostic (3.45e-1)" "unprognostic (4.09e-2)" "unprognostic (8.71e-2)" "unprognostic (1.72e-1)" "unprognostic (5.79e-3)" "unprognostic (2.12e-1)" "unprognostic (6.27e-2)" "unprognostic (1.09e-2)" "unprognostic (4.47e-2)" "unprognostic (3.69e-2)" "unprognostic (6.06e-3)" "unprognostic (3.86e-1)" "prognostic unfavorable (1.07e-8)" "unprognostic (5.16e-2)" "unprognostic (7.39e-2)" "unprognostic (3.53e-3)" "prognostic unfavorable (4.54e-4)" 285.9 50.1 15.7 153.3 9.0 0.7 173.9 33.9 20.4 499.3 32.1 796.8 73.3 556.3 24.6 91.1 411.5 194.4 155.6 10.3 14.9 66.1 48.3 140.3 37.5 23.1 18.4 491.4 57.8 29.1 117.8 287.1 21.5 246.8 40.5 3.4 97.7 142.3 85.4 123.4 217.7 177.9 11.3 70.7 230.5 32.8 14.9 30.7 92.6 39.5 16.6 478.7 284.7 9.7 2.9 20.2 31.2 99.6 1157.2 2331.5 3.9 927.1 586.3 231.7 80.7 16.2 62.8 0.1 75.1 522.2 183.6 4.3 13.5 2.3 19.5 0.5 14.9 0.0 3.7 5.2 1025.3 0.3 2.2 1711.4 1.0 578.6 7.8 20.9 5.6 0.2 0.7 0.6 60.9 1.4 0.3 3.2 22.4 13.4 263.2 0.1 19.5 4.3 1.6 11.1 1.0 39.9 87.6 1.1 17.9 10.4 4.2 4.2 0.5 1297.6 86.7 362.7 358.1 0.6 0.4 0.4 464.1 6.9 116.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 9.0 33.9 20.4 10.3 14.9 23.1 18.4 21.5 11.3 14.9 9.7 74.6 0.0 5.8 26.1 2.5 122.2 11.0 1.5 18.2 18.9 9.2 35.9 42.7 5.7 4.4 9.2 0.0 11.6 2.3 0.6 3.9 23.2 4.6 20.9 578.3 50.6 1.8 0.0 27.1 3.3 18.6 816.1 6.1 16.1 1.3 48.7 101.0 13.4 22.4 15.2 8.2 0.3 0.0 3.3 134.7 18.6 353.0 7.8 147.7 40.3 2.0 18.7 0.0 30.7 2.4 6.1 2.6 251.3 3.5 6.3 2.1 10.3 1.0 4.3 184.1 152.3 324.4 2.6 6.2 5.5 89.9 20.8 13.7 246.5 1.4 3.8 COL6A2 ENSG00000142173 "Collagen type VI alpha 2 chain" P12110 21 46098112-46132848 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 453.2;Fibroblasts: 1455.4;Leydig cells: 605.5;Peritubular cells: 472.1;Smooth muscle cells: 555.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "gdT-cell: 4.5;MAIT T-cell: 3.1;memory CD8 T-cell: 2.4;naive CD8 T-cell: 1.2" "Lineage enriched" "Detected in single" 13 "T-cells: 4.5" "Cell line enhanced" "Detected in many" "ASC diff: 1155.7;ASC TERT1: 2116.9;BJ: 1073.7;BJ hTERT+: 982.8;fHDF/TERT166: 775.0;HHSteC: 1129.2;HSkMC: 1524.4;U-138 MG: 1128.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 49.6" "HPA007029, HPA030920, HPA038799" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 8200000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "HPA007029: AB_1078549, HPA030920: AB_2673659, HPA038799: AB_2676214" "unprognostic (3.53e-1)" "unprognostic (3.76e-2)" "unprognostic (3.20e-2)" "unprognostic (4.87e-2)" "unprognostic (2.92e-2)" "unprognostic (1.38e-1)" "unprognostic (2.39e-1)" "unprognostic (5.28e-3)" "unprognostic (2.11e-2)" "unprognostic (1.68e-2)" "unprognostic (1.56e-1)" "unprognostic (2.01e-1)" "prognostic unfavorable (8.72e-14)" "unprognostic (2.13e-2)" "unprognostic (7.61e-2)" "unprognostic (2.31e-2)" "unprognostic (2.22e-3)" 732.4 96.2 10.1 219.9 10.8 4.5 455.0 8.7 14.4 873.3 21.6 1287.5 97.7 1001.7 36.5 178.8 675.1 283.8 484.3 10.0 14.9 96.5 97.6 394.2 55.7 14.0 19.4 723.6 78.6 24.0 112.2 335.3 11.2 569.9 60.2 0.9 156.2 274.6 123.4 390.6 402.2 275.4 9.8 175.1 441.6 77.0 11.7 35.6 201.3 67.2 25.6 918.6 595.9 12.3 9.4 12.5 34.8 31.2 1155.7 2116.9 10.0 1073.7 982.8 265.5 121.5 2.3 42.4 0.2 79.2 775.0 170.8 0.9 8.1 0.7 21.7 0.8 12.3 0.2 0.2 0.2 1129.2 0.5 4.8 1524.4 0.2 503.6 10.2 0.1 0.6 0.6 0.6 0.8 108.7 5.2 0.4 2.4 19.3 0.0 130.5 0.4 66.9 1.8 0.0 0.1 1.1 54.2 41.6 0.6 0.7 19.4 1.2 6.6 0.2 1128.1 131.5 421.5 270.3 0.7 0.4 0.9 578.1 0.5 164.8 0.0 0.0 0.0 4.5 0.0 3.1 0.0 0.4 2.4 0.0 0.0 0.4 1.2 0.0 0.3 0.0 0.0 0.1 0.5 10.1 10.8 8.7 14.4 10.0 14.9 14.0 19.4 11.2 9.8 11.7 12.3 127.3 3.2 0.6 2.0 3.1 164.4 4.3 0.6 9.1 0.7 12.7 33.5 8.7 4.3 0.6 7.3 0.0 17.6 41.2 0.4 0.0 15.1 4.0 13.2 453.2 101.4 0.0 2.7 0.1 0.4 25.1 1455.4 13.3 10.3 0.0 36.1 123.1 1.4 35.3 0.0 0.8 0.1 0.0 3.1 219.7 23.7 605.5 11.7 181.5 44.0 2.4 3.1 32.0 0.0 0.1 5.9 1.0 472.1 12.1 11.2 0.0 0.4 0.1 0.5 295.9 284.8 555.2 3.7 11.5 4.6 140.4 40.4 32.7 125.3 0.4 3.9 COL9A3 "DJ885L7.4.1, EDM3, FLJ90759, IDD, MED" ENSG00000092758 "Collagen type IX alpha 3 chain" Q14050 20 62816244-62841159 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.7;choroid plexus: 34.4;thyroid gland: 25.4" "Cell type enhanced" "Detected in many" "Early spermatids: 116.6;Late spermatids: 401.9;Muller glia cells: 95.8;Oligodendrocyte precursor cells: 84.9;Oligodendrocytes: 68.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 30.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "BEWO: 143.4;Hep G2: 59.6;SK-MEL-30: 51.1;WM-115: 57.8" "Low region specificity" "Detected in all" "HPA040125, HPA058323" Supported Approved "Nucleoplasm,Intermediate filaments" "Secreted to extracellular matrix" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Intermediate filaments" "HPA040125: AB_10805604, HPA058323: AB_2683679" "unprognostic (1.14e-3)" "unprognostic (2.14e-2)" "unprognostic (3.93e-1)" "unprognostic (1.21e-3)" "unprognostic (4.25e-2)" "unprognostic (2.39e-2)" "unprognostic (2.33e-1)" "unprognostic (1.24e-2)" "unprognostic (1.27e-1)" "unprognostic (1.25e-1)" "unprognostic (2.39e-1)" "unprognostic (2.13e-1)" "unprognostic (1.64e-2)" "unprognostic (2.94e-1)" "unprognostic (1.51e-1)" "unprognostic (4.79e-2)" "unprognostic (2.67e-1)" 1.6 1.5 17.5 0.7 35.7 0.0 2.8 22.4 21.6 3.3 34.4 12.1 0.7 1.2 0.2 1.3 1.7 0.1 6.3 13.0 16.5 2.9 0.6 0.4 0.2 37.4 31.0 1.7 7.6 0.1 14.0 0.5 24.2 3.2 0.1 1.6 23.6 1.2 0.5 1.9 3.1 0.1 20.5 0.3 2.7 20.7 31.6 0.1 25.4 0.0 0.0 2.8 3.8 39.7 0.2 0.3 0.3 0.2 0.0 0.8 143.4 0.1 0.0 0.1 0.0 1.6 0.2 0.0 13.1 0.0 0.8 0.1 0.2 0.0 0.0 0.0 0.9 0.0 8.2 59.6 0.3 0.0 0.5 2.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.3 0.0 0.0 1.0 0.7 6.4 8.2 0.0 2.5 0.0 1.8 0.0 0.1 0.0 1.5 0.2 0.1 51.1 4.6 0.2 5.4 0.0 0.0 0.7 0.1 1.0 0.2 0.1 0.0 0.2 0.0 57.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.5 35.7 22.4 21.6 13.0 16.5 37.4 31.0 24.2 20.5 31.6 39.7 1.6 3.2 0.0 1.0 26.1 3.2 2.2 1.2 1.8 0.9 2.1 2.5 1.6 0.0 0.2 5.5 10.4 5.1 0.4 0.7 1.9 3.6 116.6 2.7 0.4 3.7 4.2 1.3 2.5 0.0 46.4 15.3 6.1 0.7 0.0 0.6 2.5 6.8 2.2 0.0 2.0 3.3 0.0 2.2 0.9 401.9 4.1 1.7 3.6 0.0 0.5 95.8 0.0 84.9 68.9 0.1 7.3 1.5 44.0 1.2 2.3 23.7 2.5 3.7 0.0 0.8 1.0 2.9 7.8 0.9 7.0 4.0 1.4 3.7 2.0 1.0 CPEB3 KIAA0940 ENSG00000107864 "Cytoplasmic polyadenylation element binding protein 3" Q8NE35 10 92046692-92291078 "Predicted intracellular proteins" "Translation regulation" "Activator, Repressor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 32.2" "Cell type enhanced" "Detected in many" "Astrocytes: 176.0;Early spermatids: 226.2;Excitatory neurons: 233.7;Inhibitory neurons: 286.9;Late spermatids: 408.9;Oligodendrocyte precursor cells: 148.8;Oligodendrocytes: 128.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Karpas-707: 12.1;U-266/70: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070942 Approved "Nucleoplasm,Plasma membrane,Midbody,Cytosol" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Plasma membrane, Midbody" "HPA070942: " "unprognostic (4.90e-2)" "unprognostic (2.12e-2)" "unprognostic (3.00e-1)" "unprognostic (5.66e-2)" "unprognostic (1.92e-1)" "unprognostic (2.95e-5)" "prognostic favorable (5.06e-5)" "unprognostic (4.09e-4)" "unprognostic (2.73e-1)" "unprognostic (2.40e-1)" "unprognostic (1.47e-2)" "unprognostic (2.42e-2)" "prognostic favorable (3.84e-9)" "unprognostic (3.33e-2)" "unprognostic (7.42e-2)" "unprognostic (1.36e-2)" "unprognostic (1.40e-1)" 1.9 3.9 6.1 1.8 7.2 1.7 3.2 6.2 17.3 2.5 2.1 2.3 3.1 1.9 4.5 4.6 1.8 2.0 5.1 6.4 4.3 4.6 32.2 2.2 1.9 10.4 5.6 3.5 3.5 3.2 4.0 1.6 11.0 4.2 2.6 7.1 7.5 2.4 19.7 4.0 3.0 2.0 1.4 2.6 2.8 12.9 4.4 1.5 6.5 9.5 2.1 1.9 3.1 7.0 0.9 0.2 0.3 1.9 0.5 0.5 0.7 0.8 0.6 1.2 0.9 0.6 1.9 1.1 1.0 0.3 0.5 2.5 0.9 0.6 0.7 1.1 0.9 1.4 1.3 0.8 1.4 0.6 1.4 0.4 1.5 0.6 2.4 1.0 1.1 1.3 0.9 12.1 0.5 0.7 0.9 0.8 0.2 1.3 0.9 1.1 1.6 2.1 1.2 0.4 1.4 0.5 0.8 2.2 1.6 1.0 2.7 1.6 0.8 0.6 0.6 0.4 0.7 6.3 1.7 1.1 0.3 2.2 0.1 2.6 0.4 0.8 0.2 0.5 0.2 0.7 0.1 0.3 0.3 0.1 0.1 0.1 0.5 0.2 0.6 0.2 0.1 0.2 6.1 7.2 6.2 17.3 6.4 4.3 10.4 5.6 11.0 1.4 4.4 7.0 6.1 6.4 7.0 176.0 6.2 8.8 4.0 4.0 7.4 26.0 20.5 10.7 25.3 5.7 4.4 12.9 50.1 2.1 3.0 11.3 5.9 3.2 226.2 9.0 3.0 7.1 19.8 3.6 233.7 2.6 1.6 5.5 4.1 10.8 3.8 4.1 12.5 75.2 4.8 30.3 286.9 9.9 8.2 23.9 3.4 408.9 5.9 10.3 5.4 87.1 8.9 3.2 4.1 148.8 128.6 3.2 4.0 7.9 4.2 10.7 10.1 5.0 8.7 24.7 0.0 4.4 4.1 13.2 7.2 22.0 13.9 1.2 3.3 3.4 5.9 6.5 CPT2 "CPT1, CPTASE" ENSG00000157184 "Carnitine palmitoyltransferase 2" P23786 1 53196792-53214197 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 91.2" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 85.1;Hepatocytes: 88.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028201, HPA028202, HPA028214" Enhanced Approved Nucleoplasm,Nucleoli,Mitochondria Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Mitochondria" Nucleoli "HPA028201: AB_10599177, HPA028202: AB_10599942, HPA028214: AB_10601958" "unprognostic (2.43e-1)" "unprognostic (2.27e-1)" "prognostic favorable (5.27e-4)" "unprognostic (6.48e-2)" "unprognostic (1.88e-1)" "unprognostic (9.34e-2)" "unprognostic (6.48e-2)" "unprognostic (1.75e-2)" "unprognostic (2.86e-1)" "unprognostic (1.67e-1)" "unprognostic (3.00e-2)" "unprognostic (8.97e-2)" "prognostic favorable (1.46e-12)" "unprognostic (4.00e-2)" "unprognostic (2.06e-1)" "unprognostic (1.79e-2)" "unprognostic (2.95e-2)" 12.9 14.3 6.6 9.4 8.2 5.4 13.6 7.9 7.3 10.3 16.8 35.4 32.4 6.8 10.5 14.2 10.5 9.5 19.5 6.1 7.1 35.1 91.2 11.5 10.6 8.1 7.5 10.2 21.7 27.3 6.7 18.0 8.0 12.2 32.8 7.1 14.6 11.7 17.3 6.7 24.9 11.4 7.7 8.7 18.4 12.9 9.0 10.2 12.5 33.1 13.2 11.1 4.5 8.9 16.0 8.3 17.2 17.8 14.6 11.3 17.5 9.8 13.2 17.5 17.5 8.6 14.5 28.9 14.6 9.2 20.1 19.1 35.1 25.1 15.1 17.0 16.0 21.8 9.9 6.4 25.9 15.9 19.5 23.0 23.2 13.8 11.1 18.6 15.4 26.5 20.9 9.9 13.1 12.8 10.7 13.0 29.8 38.4 20.0 13.2 16.2 34.4 22.9 22.0 25.3 14.4 22.1 30.3 39.7 36.6 32.3 32.2 8.7 8.4 6.1 16.5 8.5 26.3 19.8 16.2 11.6 20.6 12.4 5.6 14.1 14.6 7.2 20.0 8.1 5.3 6.3 8.4 17.9 7.4 10.5 7.2 5.3 6.9 20.5 8.9 9.9 10.3 6.6 8.2 7.9 7.3 6.1 7.1 8.1 7.5 8.0 7.7 9.0 8.9 5.0 12.8 24.1 4.2 7.8 1.8 5.2 20.5 5.2 6.0 7.5 7.0 18.1 15.7 11.4 11.0 14.6 85.1 4.5 49.3 25.4 12.9 1.1 10.9 8.1 5.9 14.5 9.4 1.5 10.5 20.3 7.2 18.3 10.3 2.5 12.7 8.9 88.8 26.3 15.2 2.0 26.6 16.2 15.1 7.2 2.8 6.8 10.5 7.2 1.9 20.2 11.6 6.2 2.5 4.5 10.5 25.6 5.3 9.1 4.9 38.6 41.0 7.6 11.0 6.6 7.5 8.4 49.9 31.3 13.8 2.6 54.6 6.9 25.6 29.5 5.7 CRADD RAIDD ENSG00000169372 "CASP2 and RIPK1 domain containing adaptor with death domain" P78560 12 93677375-93894840 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Apoptosis "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 161.3;Early spermatids: 164.5;Inhibitory neurons: 122.3;Oligodendrocyte precursor cells: 174.4;Oligodendrocytes: 287.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005337 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol Nucleoplasm "CAB005337: AB_2085481" "unprognostic (1.07e-2)" "prognostic favorable (9.06e-5)" "unprognostic (9.65e-3)" "unprognostic (5.51e-2)" "unprognostic (2.88e-1)" "unprognostic (3.10e-1)" "unprognostic (3.79e-2)" "unprognostic (8.99e-2)" "unprognostic (1.54e-1)" "unprognostic (7.89e-2)" "unprognostic (6.06e-2)" "unprognostic (3.18e-2)" "prognostic favorable (4.04e-9)" "unprognostic (2.57e-2)" "unprognostic (6.86e-2)" "unprognostic (2.08e-1)" "unprognostic (3.02e-2)" 10.0 19.3 9.1 5.0 10.5 9.3 11.2 9.9 9.1 12.8 12.8 13.6 16.9 13.0 12.6 13.0 9.9 10.4 41.2 8.7 10.1 17.9 37.3 9.9 7.3 9.7 9.9 10.3 12.7 18.6 15.3 7.2 9.8 11.4 8.2 12.8 11.0 8.9 28.2 11.4 18.0 8.2 8.7 10.4 12.9 13.7 10.0 13.3 9.6 30.0 6.2 12.7 11.3 10.3 7.8 17.4 8.4 9.6 11.8 21.2 10.6 8.8 10.7 7.6 8.9 16.4 3.2 13.9 5.3 10.2 5.8 8.0 9.3 11.5 9.3 14.7 12.3 7.4 7.0 12.2 12.2 6.8 6.8 19.8 17.4 12.2 9.5 8.0 9.3 15.2 21.3 6.4 9.1 12.6 10.1 12.3 10.6 8.9 13.2 16.8 4.3 19.3 7.4 5.7 12.9 12.5 12.0 11.7 21.3 8.1 20.5 13.2 10.0 17.5 8.7 8.4 9.0 15.0 8.7 12.9 8.2 10.0 8.4 62.7 11.6 45.5 23.8 14.7 21.1 15.1 16.5 24.8 9.7 13.5 17.6 13.0 33.9 20.6 23.2 13.1 20.9 12.0 9.1 10.5 9.9 9.1 8.7 10.1 9.7 9.9 9.8 8.7 10.0 10.3 7.8 9.6 6.3 161.3 7.8 7.4 9.3 21.1 6.2 6.4 8.9 7.2 38.7 7.2 18.0 7.3 8.4 14.5 9.0 19.1 23.5 16.8 164.5 11.8 8.7 11.9 7.8 9.1 62.8 22.4 12.7 10.3 10.2 6.7 4.5 3.7 10.0 41.9 11.5 23.5 122.3 14.6 26.4 10.6 6.1 35.2 17.7 16.0 3.6 96.5 9.5 16.9 15.5 174.4 287.2 19.5 19.8 23.7 8.4 10.1 58.5 63.1 20.0 15.5 6.6 15.0 11.4 25.6 11.7 10.1 8.1 10.8 10.2 8.3 13.9 10.1 CREBL2 ENSG00000111269 "CAMP responsive element binding protein like 2" O60519 12 12611827-12645108 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 130.6" "Cell type enhanced" "Detected in all" "Kupffer cells: 120.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043738 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 5: NTERA-2 - Transcription" "Cluster 4: Macrophages - Innate immune response" Mitochondria "Nucleoplasm, Cytosol" "HPA043738: AB_10795041" "unprognostic (2.87e-2)" "unprognostic (1.15e-1)" "unprognostic (2.32e-1)" "unprognostic (7.51e-2)" "unprognostic (7.38e-2)" "unprognostic (4.51e-1)" "unprognostic (1.44e-1)" "unprognostic (5.92e-2)" "unprognostic (1.10e-1)" "unprognostic (4.12e-2)" "unprognostic (5.82e-3)" "unprognostic (6.73e-2)" "prognostic favorable (2.26e-5)" "unprognostic (6.31e-2)" "unprognostic (1.57e-1)" "unprognostic (3.59e-1)" "unprognostic (1.53e-1)" 39.8 130.6 24.7 30.4 26.3 5.3 31.9 22.8 29.2 26.4 29.5 23.4 23.1 19.0 28.8 17.1 24.6 28.2 22.5 26.2 28.8 49.7 50.1 32.5 37.5 24.6 24.5 37.2 24.7 56.3 32.2 24.2 24.6 28.2 23.8 35.2 26.4 23.0 10.1 24.6 23.6 18.9 24.8 37.5 25.1 20.9 29.1 24.7 44.3 15.6 29.8 28.0 15.1 27.7 12.5 15.9 13.6 15.5 46.9 47.0 26.3 24.0 40.4 17.3 23.7 11.5 17.9 10.8 9.1 29.3 26.2 10.3 20.7 18.4 29.1 61.0 12.6 8.5 15.1 14.2 30.7 12.2 15.2 30.8 32.2 20.3 33.1 58.7 25.7 8.5 8.7 16.5 29.4 20.1 6.4 9.9 40.8 11.9 14.4 8.7 23.6 6.9 33.1 35.7 16.0 18.2 24.4 11.7 43.3 58.5 6.5 13.6 20.8 23.7 15.1 23.7 23.9 13.9 19.7 2.7 28.1 10.3 24.9 1.1 2.5 2.6 1.7 5.6 3.1 0.9 3.4 2.7 2.8 1.1 3.3 2.7 0.4 1.1 2.6 1.4 5.6 1.5 24.7 26.3 22.8 29.2 26.2 28.8 24.6 24.5 24.6 24.8 29.1 27.7 18.0 25.6 26.5 23.5 14.8 22.2 18.6 11.1 18.8 17.5 23.5 15.9 14.6 30.0 12.2 33.1 2.1 18.1 15.7 17.7 41.1 21.6 40.4 14.2 10.4 19.1 30.0 27.8 15.9 21.8 19.3 25.3 17.9 10.6 10.2 12.1 23.2 48.4 39.3 37.0 17.7 16.4 26.4 120.0 83.0 12.1 36.1 58.2 33.8 33.7 45.6 38.0 10.3 28.6 18.6 21.8 15.0 35.3 17.3 29.5 29.3 58.8 19.9 11.8 39.5 13.7 12.4 45.8 20.8 18.0 29.1 27.5 23.3 11.5 17.6 28.1 CRHBP "CRF-BP, CRFBP" ENSG00000145708 "Corticotropin releasing hormone binding protein" P24387 5 76953045-76981158 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 166.5" "Group enriched" "Detected in some" 6 "Granulosa cells: 480.8;Hepatic stellate cells: 1319.7" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 4.4;BJ hTERT+ SV40 Large T+ RasG12V: 4.4;HBF TERT88: 7.7;hTEC/SVTERT24-B: 2.6;RPMI-8226: 2.5;U-698: 7.6;U-87 MG: 4.3;WM-115: 3.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA036234, HPA046120" Approved Supported "Secreted to blood" NA NA 69000000 "Cluster 85: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA036234: , HPA046120: AB_10959760" "unprognostic (1.41e-1)" "unprognostic (2.00e-2)" "unprognostic (1.14e-1)" "unprognostic (1.78e-3)" "unprognostic (1.18e-1)" "unprognostic (1.65e-1)" "unprognostic (2.36e-3)" "unprognostic (4.44e-5)" "unprognostic (2.16e-1)" "unprognostic (7.08e-2)" "unprognostic (4.98e-4)" "unprognostic (1.09e-1)" "unprognostic (6.63e-5)" "unprognostic (2.76e-2)" "unprognostic (4.64e-1)" "unprognostic (1.74e-1)" "unprognostic (2.95e-2)" 22.2 13.7 4.1 0.7 5.6 3.2 6.2 3.2 7.5 3.7 2.2 0.4 0.6 2.6 0.9 0.2 1.8 0.8 7.4 5.8 15.8 36.5 166.5 0.5 0.9 7.0 9.1 1.3 0.1 0.6 0.1 10.2 11.9 1.1 0.4 0.1 1.1 4.1 0.9 0.5 0.7 1.5 3.7 37.2 0.3 0.8 20.1 0.5 4.1 1.3 0.6 0.9 0.8 7.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 4.4 4.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 7.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 2.0 0.0 0.0 0.0 7.6 4.3 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 4.1 5.6 3.2 7.5 5.8 15.8 7.0 9.1 11.9 3.7 20.1 7.0 134.9 0.0 0.0 1.3 8.8 0.4 0.0 0.0 0.0 0.0 0.4 1.1 0.7 17.2 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.3 0.0 0.0 45.9 0.0 39.4 0.8 0.2 0.2 0.3 0.0 0.0 0.0 480.8 1319.7 9.9 1.8 0.0 32.4 0.0 0.0 75.0 2.1 1.0 0.3 3.8 0.0 4.7 0.3 0.0 0.0 0.5 11.1 0.0 0.0 0.0 0.9 0.0 0.0 3.6 0.0 0.0 0.0 0.1 2.3 0.5 1.9 0.1 0.0 0.0 1.7 0.0 0.0 0.1 CRPPA "hCG_1745121, ISPD, Nip" ENSG00000214960 "CDP-L-ribitol pyrophosphorylase A" A4D126 7 16087525-16502504 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "choroid plexus: 27.0" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 8.0;Cytotrophoblasts: 3.5;Extravillous trophoblasts: 10.6;Syncytiotrophoblasts: 2.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 29 "basophil: 13.8" "Lineage enriched" "Detected in single" 29 "granulocytes: 13.8" "Cell line enhanced" "Detected in many" "HEL: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053554 Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 36: HEL - Hemostasis" "Cluster 24: Non-specific - Transcription regulation" "Nucleoli fibrillar center" Nucleoplasm "HPA053554: AB_2682185" "unprognostic (4.65e-3)" "unprognostic (5.92e-2)" "unprognostic (2.61e-1)" "unprognostic (9.41e-2)" "unprognostic (1.49e-2)" "unprognostic (1.29e-1)" "unprognostic (1.19e-1)" "unprognostic (7.07e-2)" "unprognostic (3.47e-2)" "unprognostic (3.39e-2)" "unprognostic (6.01e-2)" "unprognostic (2.07e-1)" "prognostic favorable (1.38e-11)" "unprognostic (4.01e-2)" "unprognostic (1.78e-4)" "unprognostic (6.26e-2)" "unprognostic (2.79e-1)" 1.1 1.2 1.3 0.8 1.8 1.6 0.9 0.7 3.7 1.3 27.0 1.0 0.6 1.0 0.5 0.5 0.9 1.1 2.6 3.8 1.1 2.9 4.1 1.0 1.4 0.8 0.8 0.7 1.5 1.1 0.7 1.0 0.8 1.0 1.2 1.2 1.2 0.8 1.5 1.2 0.6 1.2 0.2 0.9 3.5 2.2 3.2 1.2 0.8 1.3 1.4 1.1 0.5 2.0 0.4 2.2 1.0 1.6 1.0 1.3 6.8 1.5 1.4 1.5 1.3 2.2 1.9 4.3 3.2 2.7 0.9 2.5 1.2 0.0 2.9 1.5 0.9 9.6 1.4 0.7 1.5 1.9 2.4 2.2 0.8 1.6 0.4 0.9 1.2 3.0 3.2 0.2 4.2 0.7 3.0 1.2 1.8 1.1 0.5 1.1 1.9 0.2 2.1 0.8 1.5 0.9 1.4 2.1 1.7 2.5 1.6 2.0 2.0 1.9 1.5 0.4 1.7 0.4 0.0 4.8 1.5 2.3 2.2 13.8 0.1 0.4 0.2 0.0 0.1 0.2 0.1 0.2 0.0 0.4 0.3 0.2 0.4 0.4 0.1 0.3 0.1 0.0 1.3 1.8 0.7 3.7 3.8 1.1 0.8 0.8 0.8 0.2 3.2 2.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 3.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 10.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 CSRNP3 "FAM130A2, FLJ32093, PPP1R73, TAIP-2" ENSG00000178662 "Cysteine and serine rich nuclear protein 3" Q8WYN3 2 165469647-165689407 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 358.3;Inhibitory neurons: 315.3;Oligodendrocyte precursor cells: 344.8;Oligodendrocytes: 95.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.8;PC-3: 2.4;SCLC-21H: 7.1;SH-SY5Y: 5.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017905 Approved Uncertain "Nucleoplasm,Nucleoli rim" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoli rim" Nucleoplasm "HPA017905: AB_1857757" "unprognostic (2.85e-1)" "unprognostic (1.65e-2)" "unprognostic (1.39e-2)" "unprognostic (1.11e-1)" "unprognostic (1.27e-1)" "unprognostic (3.61e-1)" "unprognostic (8.87e-2)" "unprognostic (1.02e-2)" "unprognostic (2.18e-2)" "unprognostic (2.19e-1)" "unprognostic (4.87e-2)" "unprognostic (1.01e-1)" "unprognostic (1.82e-3)" "unprognostic (7.41e-2)" "unprognostic (5.36e-2)" "unprognostic (3.17e-1)" "unprognostic (1.08e-2)" 0.9 2.3 9.4 0.4 9.3 0.0 3.2 0.0 14.4 2.3 7.0 0.8 0.7 2.7 0.8 0.7 0.9 0.9 1.4 10.6 10.5 1.5 0.6 0.4 0.2 0.0 0.7 3.4 3.7 1.1 3.4 0.2 0.0 1.5 0.9 6.4 2.2 2.1 0.1 0.7 0.6 2.5 0.0 0.8 0.7 0.6 8.6 0.5 2.3 0.7 0.2 0.6 1.0 6.5 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.2 0.5 0.2 0.4 0.0 0.3 0.1 0.5 0.0 0.2 0.0 0.7 0.4 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.3 1.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 2.4 0.0 0.0 0.6 0.5 0.0 7.1 5.8 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.6 0.2 0.0 0.3 0.5 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 9.3 0.0 14.4 10.6 10.5 0.0 0.7 0.0 0.0 8.6 6.5 2.5 3.2 5.1 81.6 0.2 5.2 4.0 2.3 6.8 55.7 16.2 13.5 8.7 5.7 1.6 11.0 70.9 0.3 0.0 0.7 3.9 2.7 2.9 2.3 9.6 3.6 7.7 0.0 358.3 2.3 0.1 8.2 2.0 2.3 0.0 47.9 1.4 3.6 2.6 11.8 315.3 4.7 4.1 0.3 1.6 1.7 7.5 0.4 7.2 7.5 0.0 19.6 0.0 344.8 95.4 0.9 1.9 8.2 0.0 0.6 1.7 7.2 0.5 20.4 6.6 4.4 23.0 0.6 1.6 6.3 4.5 0.3 0.2 13.2 2.6 2.0 CTBS CTB ENSG00000117151 Chitobiase Q01459 1 84549611-84574480 "Plasma proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Low region specificity" "Detected in all" "Region enriched" "Detected in some" 7 "basal ganglia: 7.4" "CAB017043, HPA023594, HPA048810" Approved Uncertain Cytosol "Intracellular and membrane" NA NA 370000000 "Cluster 34: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "CAB017043: , HPA023594: AB_1847311, HPA048810: " "unprognostic (7.76e-2)" "unprognostic (1.28e-2)" "unprognostic (1.11e-1)" "unprognostic (1.36e-1)" "unprognostic (9.36e-2)" "unprognostic (3.54e-1)" "unprognostic (2.92e-1)" "unprognostic (1.76e-1)" "unprognostic (1.81e-1)" "unprognostic (1.84e-1)" "unprognostic (9.23e-2)" "unprognostic (1.27e-1)" "unprognostic (2.94e-2)" "unprognostic (7.08e-2)" "unprognostic (4.89e-2)" "unprognostic (3.12e-1)" "unprognostic (4.04e-2)" 1.5 1.4 0.4 1.4 0.8 3.3 1.6 1.0 0.6 1.2 2.1 1.2 0.9 1.5 3.1 1.0 1.1 1.2 1.0 0.2 0.6 1.7 3.7 1.4 1.6 1.3 0.9 0.8 1.7 1.6 0.5 1.2 1.5 2.2 1.4 1.4 3.3 0.8 0.8 2.4 1.2 1.1 0.5 2.5 1.4 0.5 0.8 1.0 1.3 0.9 1.0 1.0 0.5 1.3 0.9 0.3 0.2 0.2 2.7 3.2 0.6 0.6 2.2 0.3 0.8 0.1 1.1 1.2 0.2 1.4 0.3 0.4 0.0 0.9 0.9 1.1 0.3 0.8 0.1 0.1 1.6 0.8 0.4 2.4 1.6 0.8 1.2 1.9 0.9 0.5 0.7 2.2 0.6 0.0 0.5 0.9 0.2 0.2 0.3 0.2 0.3 0.8 1.9 0.4 0.1 0.4 0.2 0.9 1.1 0.5 0.5 0.9 1.5 1.1 0.1 1.5 0.7 0.6 0.2 0.3 0.8 1.1 0.8 0.5 0.1 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.3 0.1 0.0 0.0 0.4 0.8 1.0 0.6 0.2 0.6 1.3 0.9 1.5 0.5 0.8 1.3 43.6 9.6 23.4 10.4 37.4 30.3 30.2 28.0 34.1 5.9 33.1 15.6 5.8 31.5 25.5 23.9 41.7 26.8 25.4 30.2 43.0 20.2 3.3 24.1 24.4 29.9 23.0 14.1 6.2 19.2 24.2 28.1 25.0 19.4 43.8 9.7 49.6 70.8 48.2 3.3 4.3 18.9 16.2 75.5 27.9 3.7 21.1 58.8 7.2 20.6 56.5 21.8 18.6 5.5 9.0 19.1 25.2 24.5 59.8 36.7 30.0 44.4 38.2 41.9 13.1 20.2 16.6 10.4 12.8 27.3 24.7 25.6 26.8 25.3 18.4 29.9 CTNNBIP1 "ICAT, MGC15093" ENSG00000178585 "Catenin beta interacting protein 1" Q9NSA3 1 9848276-9910336 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 177.7;skin 1: 434.9" "Cell type enhanced" "Detected in many" "Muller glia cells: 185.7;Suprabasal keratinocytes: 291.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 13.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067089 Enhanced Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA 35000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "Nucleoli, Vesicles" "HPA067089: " "unprognostic (2.71e-1)" "unprognostic (4.46e-2)" "unprognostic (1.94e-1)" "prognostic favorable (5.68e-6)" "unprognostic (3.08e-1)" "unprognostic (2.63e-2)" "unprognostic (2.22e-2)" "unprognostic (1.19e-1)" "unprognostic (2.23e-2)" "unprognostic (2.62e-1)" "unprognostic (2.17e-2)" "unprognostic (1.77e-1)" "unprognostic (1.24e-3)" "unprognostic (3.62e-2)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (4.37e-2)" 34.4 11.1 29.7 11.2 28.2 22.4 35.2 37.3 31.2 59.2 13.1 15.0 18.8 11.8 77.4 177.7 12.5 10.3 43.8 29.5 30.0 17.6 15.7 26.4 8.7 33.8 29.0 14.6 35.9 10.9 19.7 28.2 36.4 24.5 10.2 27.5 53.1 14.1 39.0 434.9 14.9 10.9 27.1 9.3 22.8 27.0 37.5 19.6 21.0 22.3 25.1 13.3 85.1 27.3 74.8 10.9 65.9 50.4 9.8 16.2 21.1 14.4 25.2 20.9 13.3 5.4 92.6 22.9 41.0 18.7 21.6 37.3 7.7 85.9 9.6 58.0 11.9 14.9 3.4 69.3 20.3 11.3 8.4 18.2 83.5 26.7 27.0 17.7 57.2 42.4 26.8 10.5 13.0 45.6 25.3 41.6 35.0 60.0 18.7 28.4 19.3 14.7 10.7 25.2 72.1 45.4 32.9 29.4 44.4 22.3 36.3 27.2 37.7 13.4 16.4 20.4 32.2 22.9 32.5 27.0 5.0 56.6 54.5 2.6 5.2 13.8 2.6 1.8 1.6 1.7 1.3 2.1 6.4 1.5 1.3 1.2 3.7 8.6 1.2 2.0 1.3 2.6 29.7 28.2 37.3 31.2 29.5 30.0 33.8 29.0 36.4 27.1 37.5 27.3 150.6 28.9 13.9 30.0 9.6 103.1 42.3 16.1 40.5 9.0 39.9 33.3 14.0 24.3 17.0 18.4 8.4 71.3 23.5 20.5 33.2 20.9 116.3 20.0 17.9 42.7 49.1 20.0 18.0 18.7 43.2 15.7 30.1 38.5 0.0 27.2 20.0 25.6 58.0 16.8 14.1 37.5 12.2 43.0 97.4 34.8 14.9 38.3 48.0 12.2 33.6 185.7 71.1 17.1 24.1 37.6 28.3 23.0 13.3 53.5 28.6 30.5 5.2 12.8 46.0 15.0 24.5 72.1 43.6 154.0 291.5 48.4 17.2 14.3 28.6 60.5 CWH43 "CWH43-C, FLJ21511, PGAP2IP" ENSG00000109182 "Cell wall biogenesis 43 C-terminal homolog" Q9H720 4 48986275-49062081 "Predicted membrane proteins" "GPI-anchor biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 21.0;prostate: 42.8;skin 1: 25.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 10.4;Endometrial ciliated cells: 41.3;Gastric mucus-secreting cells: 10.7;Glandular and luminal cells: 21.1;Paneth cells: 15.4;Respiratory ciliated cells: 29.5;Undifferentiated cells: 15.0" "Cancer enriched" "Detected in many" 4 "prostate cancer: 20.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA042814, HPA048140" Uncertain Uncertain "Golgi apparatus,Plasma membrane" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Golgi apparatus, Plasma membrane" "HPA042814: AB_2678182, HPA048140: AB_2680280" "unprognostic (9.38e-3)" "unprognostic (6.23e-2)" "unprognostic (3.14e-2)" "prognostic favorable (1.32e-4)" "unprognostic (2.14e-1)" "unprognostic (5.00e-2)" "unprognostic (1.94e-1)" "unprognostic (2.49e-1)" "unprognostic (1.63e-1)" "unprognostic (2.07e-1)" "unprognostic (2.49e-4)" "unprognostic (1.24e-1)" "prognostic favorable (2.29e-11)" "unprognostic (5.19e-2)" "unprognostic (3.35e-1)" "unprognostic (1.82e-2)" "unprognostic (2.51e-2)" 0.0 0.0 0.0 1.4 0.0 0.0 2.0 0.0 0.0 6.0 0.0 16.9 0.4 0.6 0.4 21.0 14.5 0.0 0.0 0.0 0.0 9.0 0.7 0.7 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.0 42.8 15.6 0.0 3.0 7.7 0.0 25.5 0.0 0.8 0.1 0.0 9.6 0.0 0.1 0.1 10.2 0.0 1.5 2.1 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.2 1.9 0.1 0.8 0.0 0.0 0.6 0.1 0.6 0.0 2.3 7.3 0.0 0.0 0.0 10.4 1.9 0.0 0.2 41.3 2.4 0.1 0.0 0.0 0.1 0.0 0.0 0.2 10.7 21.1 0.0 0.0 0.0 0.4 0.0 0.0 0.2 4.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 15.4 0.0 0.0 7.6 0.0 2.9 29.5 0.0 0.0 0.0 0.5 0.0 0.5 3.2 9.1 0.0 0.2 0.0 15.0 0.3 CYB5A CYB5 ENSG00000166347 "Cytochrome b5 type A" P00167 18 74250846-74291973 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 889.6;liver: 2472.0" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 1371.0;Distal tubular cells: 2156.1;Hepatocytes: 3376.3;Proximal enterocytes: 1856.4;Proximal tubular cells: 3630.6" "Cancer enhanced" "Detected in all" "liver cancer: 43.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1117.0;RT4: 513.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006333, HPA047548, HPA058547" Enhanced Enhanced Vesicles,Cytosol No No 1400000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "CAB006333: , HPA047548: AB_2680084, HPA058547: AB_2683750" "unprognostic (1.88e-1)" "unprognostic (1.28e-1)" "prognostic favorable (5.23e-4)" "unprognostic (1.08e-2)" "unprognostic (1.41e-1)" "unprognostic (9.14e-2)" "prognostic favorable (4.15e-4)" "unprognostic (7.79e-3)" "unprognostic (1.11e-1)" "unprognostic (3.33e-2)" "unprognostic (2.68e-2)" "unprognostic (1.65e-2)" "unprognostic (1.17e-1)" "unprognostic (1.95e-1)" "unprognostic (1.75e-1)" "unprognostic (4.64e-2)" "unprognostic (8.54e-2)" 309.5 109.6 38.4 31.2 39.7 25.3 253.5 42.2 45.2 86.0 37.6 146.5 438.2 44.9 176.2 78.1 81.9 301.2 84.8 37.5 38.8 889.6 2472.0 356.6 43.7 43.1 39.7 223.9 461.3 236.0 58.5 81.8 41.9 95.9 103.4 10.3 59.1 122.8 41.4 118.4 381.7 46.7 40.8 75.6 194.8 57.9 40.0 51.6 42.5 42.1 35.2 155.5 68.3 43.5 78.8 130.8 67.4 0.6 1117.0 198.2 89.5 52.6 113.8 111.0 163.8 156.2 82.7 95.6 36.7 97.6 54.4 170.6 0.1 73.1 86.9 179.8 91.7 34.9 65.6 418.1 174.6 67.3 44.1 334.1 57.4 63.0 32.3 66.0 63.6 85.8 58.6 35.0 93.7 140.9 38.3 80.5 30.4 110.0 86.8 93.6 21.9 2.3 111.9 513.2 190.4 79.7 51.4 137.1 65.8 56.6 271.5 63.7 57.9 0.6 85.8 26.6 68.1 24.6 109.2 30.3 67.0 19.2 64.3 4.1 29.5 7.5 51.3 36.3 116.2 93.7 55.6 60.2 53.7 112.7 54.5 68.6 3.7 36.3 45.7 47.8 48.8 43.2 38.4 39.7 42.2 45.2 37.5 38.8 43.1 39.7 41.9 40.8 40.0 43.5 169.7 637.8 1371.0 11.4 76.0 98.0 82.1 368.6 50.7 9.9 345.8 213.2 90.7 836.4 1053.2 842.4 4.2 229.3 29.4 197.0 2156.1 239.4 7.5 163.1 76.6 119.9 164.2 180.0 13.1 504.6 169.8 141.4 208.9 345.6 39.9 55.0 177.4 3376.3 97.4 8.4 12.6 236.5 457.7 128.6 72.9 26.7 158.1 60.8 90.7 10.3 224.1 39.2 32.0 14.1 22.7 266.7 358.9 149.7 33.4 142.0 1856.4 3630.6 619.5 14.0 52.6 49.6 85.0 15.3 42.0 141.2 223.9 44.5 52.6 1123.6 329.9 220.7 CYB5D2 MGC32124 ENSG00000167740 "Cytochrome b5 domain containing 2" Q8WUJ1 17 4143168-4187310 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 130.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 74.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011032, HPA042299" Approved Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum, Plasma membrane" "HPA011032: , HPA042299: AB_10793879" "unprognostic (2.57e-2)" "unprognostic (2.89e-2)" "unprognostic (4.16e-2)" "prognostic favorable (6.19e-4)" "unprognostic (1.88e-2)" "unprognostic (1.75e-2)" "prognostic favorable (4.98e-6)" "unprognostic (1.57e-1)" "unprognostic (2.47e-1)" "unprognostic (9.71e-3)" "prognostic favorable (7.76e-5)" "unprognostic (2.04e-1)" "prognostic favorable (2.03e-10)" "unprognostic (2.01e-3)" "unprognostic (8.73e-2)" "unprognostic (1.82e-1)" "unprognostic (2.97e-1)" 19.0 21.7 17.4 6.1 17.3 4.3 18.2 17.4 20.1 15.9 14.2 10.7 15.2 15.6 28.5 10.9 18.7 16.3 14.0 16.7 19.6 25.5 29.0 9.7 9.3 18.1 17.6 20.8 19.7 30.9 24.1 10.8 17.8 13.5 7.4 9.2 20.0 17.6 16.2 14.4 12.1 8.4 17.6 9.6 16.0 29.3 17.9 10.2 22.7 14.9 7.2 12.9 11.7 18.7 16.2 21.6 11.8 12.7 74.7 22.5 5.2 15.7 31.5 11.0 10.9 6.3 10.3 5.3 13.6 17.4 9.2 22.5 4.9 7.1 4.4 17.9 25.7 5.0 13.5 10.5 13.7 2.1 9.5 28.8 17.0 6.2 11.7 22.3 20.1 11.5 5.1 31.2 8.3 20.6 7.8 3.4 4.3 13.7 11.5 9.2 10.6 12.5 25.1 8.5 9.3 8.1 17.2 9.9 23.5 13.1 25.6 3.2 28.5 15.7 4.0 14.5 8.0 5.8 4.9 3.9 19.9 4.5 6.2 0.6 10.8 13.6 5.9 9.2 6.7 8.1 9.3 7.4 10.5 7.1 8.6 8.0 9.5 5.5 8.7 11.3 11.2 8.2 17.4 17.3 17.4 20.1 16.7 19.6 18.1 17.6 17.8 17.6 17.9 18.7 57.4 12.8 10.3 9.1 17.2 53.7 18.4 36.0 12.5 26.9 35.4 36.7 9.8 45.8 21.8 31.3 58.4 55.7 11.4 18.5 52.8 34.3 28.5 36.6 20.0 34.4 13.8 33.3 7.6 27.0 29.1 23.8 19.4 23.4 11.4 22.3 41.0 32.9 21.4 40.4 10.4 16.0 36.7 24.0 23.8 30.6 28.9 17.3 14.2 4.7 15.4 37.6 15.5 8.5 10.0 26.9 18.9 28.6 17.6 8.3 39.7 55.7 38.5 30.4 0.0 15.2 20.1 130.3 29.2 9.5 42.9 38.6 15.8 39.3 16.6 15.8 CYP1A1 "CP11, CYP1, P1-450, P450-C, P450DX" ENSG00000140465 "Cytochrome P450 family 1 subfamily A member 1" P04798 15 74719542-74725536 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" "Lyase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 66.1;urinary bladder: 63.6" "Cell type enhanced" "Detected in some" "Adipocytes: 21.9;Endothelial cells: 13.7;Glandular and luminal cells: 5.9;Hepatocytes: 9.9;Urothelial cells: 16.4" "Group enriched" "Detected in some" 24 "liver cancer: 18.6;urothelial cancer: 54.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 36.9;hTCEpi: 19.5;HUVEC TERT2: 19.1;SK-BR-3: 14.7;SuSa: 35.6" "Not detected" "Not detected" "Not detected" "Not detected" CAB018654 Uncertain NA NA "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "CAB018654: AB_2088699" "unprognostic (1.71e-2)" "unprognostic (7.86e-2)" "unprognostic (2.57e-2)" "unprognostic (2.89e-1)" "unprognostic (5.45e-3)" "unprognostic (6.34e-2)" "unprognostic (3.08e-1)" "unprognostic (6.24e-3)" "unprognostic (1.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (4.21e-2)" "unprognostic (6.70e-2)" "unprognostic (2.20e-1)" "unprognostic (4.77e-1)" "unprognostic (1.28e-1)" 18.5 0.6 0.2 0.0 0.2 0.0 14.7 0.1 0.3 3.6 0.0 2.0 0.6 2.4 0.6 1.9 1.2 0.7 10.7 0.2 0.4 1.4 66.1 12.2 0.0 0.3 0.4 0.5 0.6 0.0 0.5 0.3 0.3 0.7 0.1 0.3 1.8 0.6 4.1 13.9 19.8 0.0 0.1 0.1 1.8 0.3 0.2 0.2 2.0 0.2 0.1 63.6 2.2 0.1 0.3 2.1 0.2 0.0 0.5 0.1 11.7 0.0 0.1 0.7 0.3 36.9 1.6 0.3 9.6 0.0 8.8 11.4 0.7 7.3 0.3 0.0 1.0 0.5 2.6 5.5 0.2 0.3 11.5 0.0 19.5 0.3 1.4 0.4 19.1 0.3 2.3 0.3 0.1 0.7 0.1 0.4 0.2 12.1 2.9 1.2 0.0 0.4 0.0 2.4 0.6 0.3 1.7 14.7 3.8 35.6 0.4 0.2 1.0 1.6 0.5 5.2 0.0 0.7 0.2 0.5 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.3 0.2 0.4 0.3 0.4 0.3 0.1 0.2 0.1 21.9 0.0 0.0 0.0 0.1 0.5 2.4 0.0 0.0 0.0 0.4 0.5 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 3.4 1.1 13.7 0.0 0.0 0.1 0.2 0.0 0.2 0.0 5.9 0.0 0.0 0.0 9.9 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.4 0.0 0.1 0.0 0.0 16.4 CYP2B6 "CPB6, CYP2B, CYPIIB6" ENSG00000197408 "Cytochrome P450 family 2 subfamily B member 6" P20813 19 40991282-41018398 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "liver: 533.7" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 420.9" "Cancer enhanced" "Detected in many" "liver cancer: 28.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 2.6;OE19: 1.8" "Region enhanced" "Detected in single" "spinal cord: 2.3" "CAB033866, HPA048124, HPA062973" Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "Nuclear membrane" "Nucleoplasm, Cytosol" "CAB033866: AB_2292644, HPA048124: AB_2680274, HPA062973: AB_2684914" "unprognostic (1.86e-1)" "unprognostic (1.23e-2)" "unprognostic (1.13e-2)" "unprognostic (6.13e-2)" "unprognostic (4.59e-2)" "unprognostic (4.63e-2)" "unprognostic (4.41e-2)" "unprognostic (1.73e-1)" "unprognostic (5.78e-2)" "unprognostic (1.04e-3)" "unprognostic (2.19e-1)" "unprognostic (9.43e-2)" "unprognostic (5.44e-1)" 0.0 0.0 0.2 0.2 0.2 0.5 0.1 0.6 0.3 0.0 0.3 4.7 5.1 0.1 0.0 0.0 0.0 0.7 0.1 0.3 0.1 15.1 533.7 0.4 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 1.7 0.8 0.0 0.1 0.2 0.0 6.7 0.6 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.1 0.0 2.6 0.1 0.0 0.0 0.1 0.2 0.1 0.3 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.5 0.2 1.8 0.1 0.0 0.1 0.1 0.6 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.2 0.4 0.3 0.2 0.1 0.2 0.2 0.1 0.3 0.3 0.0 0.4 0.0 0.7 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.5 0.1 0.0 0.4 0.1 0.0 0.2 0.2 0.6 0.3 0.3 0.1 0.3 0.1 0.2 0.0 0.2 0.4 0.0 0.0 1.1 0.0 0.8 0.0 0.2 0.4 0.0 0.0 0.1 0.0 0.2 7.2 1.4 1.8 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 16.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 11.4 420.9 0.0 0.0 0.1 1.6 0.0 11.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.3 0.0 0.0 0.1 38.3 16.9 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.1 4.3 0.7 CYP3A5 "CP35, P450PCN3, PCN3" ENSG00000106258 "Cytochrome P450 family 3 subfamily A member 5" P20815 7 99648194-99679998 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 177.7;liver: 276.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 377.4;Distal enterocytes: 382.7;Gastric mucus-secreting cells: 506.6;Hepatocytes: 454.5;Paneth cells: 451.6;Proximal enterocytes: 1074.6;Urothelial cells: 380.4" "Cancer enhanced" "Detected in many" "liver cancer: 38.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 9.7;Hep G2: 7.9;OE19: 28.3" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol Vesicles "HPA072245: , HPA075539: " "unprognostic (2.13e-1)" "unprognostic (4.36e-2)" "unprognostic (4.04e-2)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "unprognostic (2.73e-1)" "prognostic favorable (3.72e-5)" "unprognostic (1.37e-3)" "unprognostic (1.21e-2)" "unprognostic (7.29e-3)" "unprognostic (3.85e-1)" "unprognostic (4.05e-2)" "unprognostic (1.46e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" "unprognostic (2.39e-4)" "unprognostic (6.58e-3)" 3.3 14.4 0.1 3.8 0.4 0.6 6.5 0.8 0.9 5.1 0.4 28.4 127.3 3.1 3.0 22.1 3.1 32.7 1.0 0.3 0.0 10.6 276.1 9.2 1.4 0.6 0.0 0.8 47.0 0.0 0.9 0.4 0.4 21.6 21.0 0.7 2.9 5.7 0.9 20.5 177.7 1.1 0.0 0.8 86.5 0.4 0.0 2.1 1.0 0.0 3.2 10.4 13.1 0.5 1.6 3.3 1.6 1.9 0.4 0.6 0.5 1.5 0.0 0.0 0.0 9.7 7.4 1.0 1.5 0.0 1.2 1.2 0.0 0.0 0.0 1.8 1.2 1.2 0.7 7.9 0.1 2.0 0.6 0.0 2.1 0.0 0.0 1.4 0.0 0.9 3.3 2.0 0.0 0.3 2.6 3.8 0.4 28.3 0.8 0.6 1.6 2.2 0.4 1.5 1.2 1.7 0.9 0.8 3.2 1.6 0.5 0.7 1.2 1.8 1.6 1.6 1.2 1.0 2.6 1.7 1.6 2.6 1.5 0.4 0.3 0.4 0.4 0.3 0.9 0.2 0.6 0.6 0.2 0.1 0.4 0.5 0.5 0.4 0.2 0.3 0.5 0.2 0.1 0.4 0.8 0.9 0.3 0.0 0.6 0.0 0.4 0.0 0.0 0.5 0.9 12.8 14.8 1.3 4.8 46.1 112.7 31.0 59.7 13.7 1.1 0.4 1.3 377.4 27.3 3.7 12.5 1.7 1.7 382.7 0.0 63.4 2.0 3.1 2.2 6.3 54.6 21.7 8.6 50.7 1.2 8.5 506.6 10.3 10.1 1.8 8.2 454.5 0.6 8.4 11.0 140.5 6.1 9.5 4.5 0.5 2.5 4.1 3.6 2.8 4.9 4.0 10.3 7.1 6.5 80.1 451.6 2.6 6.4 156.3 1074.6 10.8 12.1 21.6 0.0 2.5 3.4 15.1 6.4 107.3 59.0 1.5 7.5 3.1 139.8 380.4 CYP3A7 "CP37, P450-HFLA" ENSG00000160870 "Cytochrome P450 family 3 subfamily A member 7" P24462 7 99705036-99735196 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "liver: 304.9" "Group enriched" "Detected in some" 17 "Cholangiocytes: 85.8;Hepatocytes: 60.5" "Cancer enriched" "Detected in some" 43 "liver cancer: 38.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.3;Hep G2: 2.5;HHSteC: 1.4" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Cytosol Vesicles "HPA072245: , HPA075539: " "unprognostic (8.10e-3)" "unprognostic (1.45e-1)" "unprognostic (3.12e-1)" "unprognostic (5.47e-2)" "unprognostic (1.73e-1)" "unprognostic (1.44e-1)" "unprognostic (4.41e-2)" "unprognostic (1.50e-1)" "unprognostic (1.34e-2)" "unprognostic (8.28e-2)" "unprognostic (8.18e-2)" "unprognostic (1.97e-1)" "unprognostic (1.06e-11)" "unprognostic (2.02e-2)" "unprognostic (5.87e-2)" "unprognostic (2.97e-1)" "unprognostic (1.34e-3)" 0.2 0.9 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 0.0 0.2 0.5 0.3 0.3 0.1 0.0 6.5 0.0 0.0 0.1 8.5 304.9 2.4 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.1 0.1 0.0 0.2 1.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.6 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.9 0.0 0.0 0.0 0.0 0.1 85.8 0.3 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 3.3 60.5 0.1 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 3.8 4.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 1.3 0.0 0.2 CYP4F12 ENSG00000186204 "Cytochrome P450 family 4 subfamily F member 12" Q9HCS2 19 15673018-15697174 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.5;liver: 40.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 58.8;Gastric mucus-secreting cells: 57.6;Paneth cells: 51.9;Proximal enterocytes: 125.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 54 "basophil: 6.1;eosinophil: 14.8" "Lineage enriched" "Detected in single" 88 "granulocytes: 14.8" "Cell line enhanced" "Detected in some" "CAPAN-2: 17.6;HaCaT: 32.0;Hep G2: 9.8;Karpas-707: 20.9;OE19: 46.3" HPA058960 Approved NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "HPA058960: AB_2683862" "unprognostic (4.30e-4)" "prognostic favorable (1.21e-4)" "unprognostic (1.86e-1)" "unprognostic (1.48e-2)" "unprognostic (1.37e-2)" "unprognostic (5.32e-3)" "unprognostic (1.84e-3)" "unprognostic (9.13e-2)" "unprognostic (9.11e-2)" "unprognostic (2.50e-1)" "unprognostic (4.32e-2)" "unprognostic (1.47e-1)" "unprognostic (1.66e-3)" "unprognostic (6.20e-2)" "unprognostic (5.45e-2)" "unprognostic (3.17e-1)" "prognostic favorable (2.33e-4)" 3.2 1.1 0.6 1.2 0.9 0.9 2.7 0.6 1.5 6.0 0.4 15.1 39.1 1.5 0.5 18.1 3.2 2.4 1.5 0.9 2.4 1.8 40.1 1.2 0.5 0.9 1.1 1.6 0.3 0.0 0.5 0.5 1.1 5.0 7.8 0.1 4.3 1.0 0.6 21.1 41.5 1.9 0.7 1.0 12.0 0.2 0.7 0.8 0.9 0.9 2.6 10.5 11.2 1.9 0.0 4.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 17.6 0.5 0.0 0.0 0.3 32.0 0.0 0.0 0.0 2.0 0.0 0.0 1.7 9.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 20.9 0.0 0.0 0.0 0.1 0.0 46.3 0.0 0.0 0.0 0.2 0.0 1.8 0.0 0.1 6.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 6.1 0.0 14.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.6 1.5 0.9 2.4 0.9 1.1 1.1 0.7 0.7 1.9 6.3 0.0 1.8 2.6 0.5 14.0 10.0 8.3 13.1 0.0 0.5 0.3 1.0 5.7 7.1 0.0 0.0 0.1 0.0 58.8 0.0 0.6 1.6 0.2 0.1 3.0 7.8 8.0 0.2 0.0 0.1 3.8 57.6 0.3 0.0 0.0 1.4 30.3 0.4 0.0 0.2 24.8 2.0 0.9 1.6 3.2 4.1 0.3 1.8 0.0 0.0 2.7 0.0 0.0 0.4 1.9 51.9 1.2 0.2 3.5 125.3 2.2 4.9 0.1 0.0 0.3 2.5 0.4 0.1 20.5 21.2 0.3 0.5 0.1 29.6 24.8 CYP4V2 CYP4AH1 ENSG00000145476 "Cytochrome P450 family 4 subfamily V member 2" Q6ZWL3 4 186191567-186213463 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sensory transduction, Vision" "Monooxygenase, Oxidoreductase" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 113.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 103.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 15.2;SK-MEL-30: 27.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029122 Approved Approved "Nuclear speckles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "Nuclear speckles" "HPA029122: AB_10601806" "unprognostic (1.65e-1)" "unprognostic (5.37e-2)" "unprognostic (2.35e-1)" "prognostic favorable (5.86e-4)" "unprognostic (1.45e-1)" "unprognostic (1.02e-1)" "prognostic favorable (1.85e-4)" "unprognostic (6.66e-2)" "unprognostic (5.84e-2)" "unprognostic (2.05e-1)" "unprognostic (6.49e-2)" "unprognostic (9.89e-2)" "prognostic favorable (1.49e-7)" "unprognostic (3.25e-2)" "unprognostic (8.96e-2)" "unprognostic (1.02e-1)" "unprognostic (3.14e-2)" 7.4 16.4 5.1 5.2 6.8 2.1 5.7 5.6 5.0 8.6 17.9 9.6 16.5 5.6 2.6 5.0 6.1 14.7 9.2 4.8 5.1 33.9 113.5 10.8 5.6 5.3 6.0 5.7 15.6 33.4 3.7 3.5 5.3 8.2 11.9 14.2 7.0 7.5 4.5 1.3 16.7 7.1 5.4 11.2 6.2 3.2 5.6 6.5 17.3 5.0 4.9 6.4 2.3 6.3 3.4 1.8 0.8 0.0 15.2 6.3 0.2 4.4 9.9 1.7 1.9 0.0 13.0 1.1 0.5 3.5 5.9 1.6 1.9 1.7 0.3 6.0 2.2 4.7 0.8 0.5 5.6 2.6 1.9 5.8 0.8 1.9 1.0 5.9 0.1 6.4 1.4 14.3 6.8 2.9 3.6 1.3 1.5 1.6 0.0 3.1 0.7 1.0 7.4 6.1 4.0 4.9 1.1 0.0 27.5 0.3 2.6 4.6 4.1 3.6 0.7 3.5 1.6 0.1 0.0 0.5 10.9 11.0 4.7 0.0 0.6 0.0 1.8 1.9 1.0 0.4 1.4 1.8 0.7 1.0 1.3 1.3 0.0 0.8 3.1 1.3 1.1 0.9 5.1 6.8 5.6 5.0 4.8 5.1 5.3 6.0 5.3 5.4 5.6 6.3 9.0 6.4 11.5 31.3 13.8 2.5 4.5 5.1 9.6 33.6 9.3 7.2 18.8 42.9 8.7 14.7 31.3 2.0 9.6 14.7 9.8 24.2 2.7 6.7 5.1 7.7 16.9 16.4 15.4 22.4 2.1 14.2 12.8 7.6 7.0 6.5 8.9 103.7 13.5 5.0 23.4 16.5 2.0 14.8 6.0 2.1 5.0 11.3 3.6 6.5 3.5 52.2 4.1 15.6 11.0 9.6 9.0 6.4 12.3 3.8 47.2 28.5 11.9 27.4 0.0 10.1 10.6 8.9 6.3 6.8 3.1 1.0 17.2 6.7 10.5 5.7 CYP4X1 MGC40051 ENSG00000186377 "Cytochrome P450 family 4 subfamily X member 1" Q8N118 1 47023669-47050751 "Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 37.1;salivary gland: 31.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 37.5;Club cells: 59.0;Excitatory neurons: 37.4;Respiratory ciliated cells: 104.6" "Cancer enhanced" "Detected in many" "breast cancer: 24.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 2.6;CACO-2: 4.6;NTERA-2: 2.1;SCLC-21H: 2.7;T-47d: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017661 Approved NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA017661: AB_2669633" "unprognostic (1.19e-1)" "unprognostic (2.28e-2)" "unprognostic (1.53e-1)" "unprognostic (1.78e-2)" "unprognostic (9.88e-2)" "unprognostic (1.56e-3)" "unprognostic (2.30e-1)" "unprognostic (2.34e-2)" "unprognostic (1.10e-2)" "unprognostic (2.35e-2)" "unprognostic (1.46e-1)" "unprognostic (2.76e-2)" "unprognostic (3.03e-2)" "unprognostic (1.79e-3)" "unprognostic (3.65e-2)" "unprognostic (8.56e-2)" "unprognostic (5.03e-2)" 11.6 3.2 8.2 0.7 8.5 0.1 14.9 5.2 10.2 37.1 2.8 1.6 1.7 2.1 2.7 14.7 9.3 1.6 8.6 8.7 12.1 5.9 10.5 8.8 1.9 4.5 5.6 1.2 1.7 1.7 3.8 1.1 5.7 8.0 1.9 2.3 31.1 2.9 4.6 7.1 1.4 1.9 4.1 0.6 22.3 4.0 9.2 1.1 5.0 4.0 9.1 3.3 7.2 6.4 0.0 0.0 0.0 0.0 2.6 0.2 0.1 0.0 0.1 0.0 0.0 4.6 0.0 0.0 0.5 0.0 1.2 0.0 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.0 0.0 0.6 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 2.1 0.7 0.0 0.0 0.3 0.0 0.4 0.2 2.7 0.0 0.0 0.2 0.0 0.1 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 8.5 5.2 10.2 8.7 12.1 4.5 5.6 5.7 4.1 9.2 6.4 4.4 22.4 17.0 2.3 0.0 2.5 26.9 37.5 25.0 2.4 31.0 0.9 0.8 1.5 59.0 0.0 0.0 0.0 0.4 0.1 0.0 0.3 8.4 7.6 0.8 4.0 0.0 0.0 37.4 0.7 0.0 7.1 4.1 1.4 0.0 0.0 1.1 2.8 3.9 0.0 29.3 0.2 18.3 0.6 0.7 8.6 10.5 0.5 5.4 4.7 0.0 0.1 0.0 1.0 2.0 0.1 0.0 20.7 0.0 8.4 0.5 1.7 104.6 0.8 0.0 2.0 19.1 0.5 3.6 21.4 1.4 0.1 0.5 0.1 1.9 31.8 CYP7A1 CYP7 ENSG00000167910 "Cytochrome P450 family 7 subfamily A member 1" P22680 8 58490178-58500163 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 80 "liver: 49.5" "Cell type enriched" "Detected in single" 17 "Hepatocytes: 7.0" "Cancer enriched" "Detected in single" 96 "liver cancer: 28.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (5.20e-2)" "unprognostic (1.93e-2)" "unprognostic (1.77e-2)" "prognostic favorable (3.19e-4)" "unprognostic (7.60e-2)" "unprognostic (5.31e-2)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (2.64e-1)" "unprognostic (8.43e-3)" "unprognostic (3.01e-1)" "unprognostic (1.57e-2)" "unprognostic (1.51e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 D2HGDH "D2HGD, FLJ42195, MGC25181" ENSG00000180902 "D-2-hydroxyglutarate dehydrogenase" Q8N465 2 241734602-241768816 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.5" "Group enriched" "Detected in many" 4 "B-cells: 2.5;T-cells: 1.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056216, HPA060548" Uncertain Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA056216: AB_2683070, HPA060548: AB_2732650" "unprognostic (2.85e-1)" "unprognostic (3.35e-2)" "unprognostic (6.98e-3)" "unprognostic (7.88e-2)" "unprognostic (2.42e-1)" "prognostic favorable (9.11e-4)" "unprognostic (2.49e-3)" "unprognostic (1.67e-2)" "unprognostic (1.03e-1)" "unprognostic (1.65e-2)" "unprognostic (7.82e-3)" "unprognostic (1.21e-1)" "unprognostic (7.63e-2)" "unprognostic (1.48e-2)" "unprognostic (1.50e-1)" "unprognostic (9.60e-2)" "unprognostic (3.05e-2)" 11.5 17.7 6.9 11.2 8.0 18.6 7.6 6.2 7.3 10.5 14.9 16.6 11.4 11.8 13.0 15.0 16.1 14.1 11.4 6.6 6.1 15.9 19.1 10.6 12.0 8.4 6.9 14.8 16.6 15.2 10.5 8.9 6.6 14.6 14.6 3.2 18.7 14.9 33.8 39.4 14.9 9.3 6.1 15.1 14.7 4.9 7.3 7.4 18.0 23.7 11.5 8.9 9.6 8.6 10.2 10.5 6.2 9.6 14.7 7.9 21.5 9.7 12.2 9.6 7.7 11.8 21.9 8.3 4.4 9.7 11.0 23.2 5.9 7.8 4.0 8.8 5.7 15.9 11.3 20.5 8.2 19.0 12.1 14.1 13.7 7.6 7.3 18.5 9.5 13.1 20.7 5.3 8.6 16.8 16.0 19.7 3.0 13.8 20.8 19.5 6.9 16.2 17.6 36.7 20.4 7.2 9.4 23.8 6.6 4.1 14.7 6.7 4.1 14.9 5.6 7.9 5.8 9.9 1.9 13.4 10.3 20.8 10.0 0.0 0.2 0.0 0.2 0.2 0.4 2.5 0.1 1.0 0.4 0.1 0.6 0.2 0.0 0.0 0.3 0.1 0.8 0.1 6.9 8.0 6.2 7.3 6.6 6.1 8.4 6.9 6.6 6.1 7.3 8.6 10.4 9.6 14.3 33.3 10.4 19.8 23.5 13.7 25.6 14.3 22.8 22.7 10.6 25.8 16.3 18.4 14.6 44.0 13.0 40.9 23.5 10.5 3.6 12.5 13.2 9.7 31.8 6.9 7.1 8.7 15.9 15.7 23.0 19.2 5.7 28.0 13.2 46.0 18.2 11.8 9.9 56.4 14.2 10.8 7.5 4.8 16.8 12.6 3.6 15.9 5.3 37.4 8.2 28.6 12.8 6.7 32.0 18.0 15.0 19.3 26.4 31.4 13.9 12.0 6.6 14.0 11.7 2.1 7.0 25.7 14.8 22.6 14.0 27.0 49.9 22.2 DACT1 "DAPPER, DAPPER1, FRODO, HDPR1, THYEX3" ENSG00000165617 "Dishevelled binding antagonist of beta catenin 1" Q9NYF0 14 58633967-58648321 "Disease related genes, Predicted intracellular proteins" "Neurogenesis, Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 56.0;Late spermatids: 17.9;Peritubular cells: 27.8;Smooth muscle cells: 15.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 17.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-MEL-30: 13.5;SuSa: 17.2;U-138 MG: 31.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003016, HPA074619" Enhanced Supported Nucleoplasm NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA003016: AB_1078623, HPA074619: " "unprognostic (2.47e-2)" "unprognostic (2.72e-2)" "unprognostic (1.79e-2)" "unprognostic (1.22e-1)" "unprognostic (1.03e-2)" "unprognostic (3.55e-2)" "unprognostic (1.37e-1)" "unprognostic (1.17e-2)" "unprognostic (4.79e-2)" "unprognostic (1.93e-1)" "unprognostic (5.42e-2)" "unprognostic (6.54e-2)" "unprognostic (4.16e-2)" "unprognostic (1.64e-2)" "unprognostic (2.54e-1)" "unprognostic (1.37e-3)" "unprognostic (1.89e-3)" 8.6 7.9 5.2 4.1 4.2 1.5 6.5 17.4 3.3 12.0 0.6 6.3 5.9 7.6 5.8 2.9 5.9 24.9 8.0 3.6 2.5 5.5 2.7 9.3 4.1 1.6 3.2 24.4 2.3 8.0 3.8 12.1 2.0 11.8 6.7 2.0 3.5 13.1 2.4 2.7 3.9 8.9 2.0 7.2 6.9 9.8 2.4 3.6 10.7 4.4 2.3 14.0 6.6 3.4 0.0 0.0 4.0 0.1 4.5 5.0 0.1 2.3 2.9 2.4 2.1 0.3 0.2 0.0 0.1 6.9 4.0 3.6 11.5 0.0 1.3 2.7 2.4 0.0 0.1 0.0 8.2 0.0 1.3 5.9 0.3 9.0 0.0 9.0 0.1 0.8 0.0 0.0 1.6 0.0 0.9 0.1 3.8 0.2 0.9 4.9 5.6 0.0 0.0 0.0 0.1 0.0 6.5 0.0 13.5 17.2 0.0 0.4 0.0 31.7 10.8 0.5 8.5 4.4 1.8 0.0 3.4 1.4 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.2 4.2 17.4 3.3 3.6 2.5 1.6 3.2 2.0 2.0 2.4 3.4 1.1 0.0 0.0 0.3 1.0 0.8 1.2 0.0 1.2 0.4 0.3 1.5 3.9 7.2 0.0 1.8 0.0 0.2 0.2 0.3 0.0 1.7 56.0 0.4 9.3 1.4 0.0 0.0 2.7 2.3 0.8 11.7 2.0 0.3 0.0 2.3 4.2 0.0 1.2 0.0 4.0 1.0 0.0 2.9 2.1 17.9 12.2 0.6 1.8 6.5 0.0 4.5 0.0 1.5 0.8 3.1 0.0 27.8 0.6 0.4 0.0 1.0 0.0 0.5 0.0 2.9 15.7 12.6 8.6 0.3 1.3 0.1 0.5 3.6 0.5 0.4 DBI "ACBD1, ACBP" ENSG00000155368 "Diazepam binding inhibitor, acyl-CoA binding protein" P07108 2 119366921-119372560 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 2215.1;Proximal tubular cells: 2834.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 2479.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051428 Approved NA NA 9100000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "HPA051428: AB_2681482" "unprognostic (1.24e-1)" "prognostic favorable (5.77e-5)" "unprognostic (4.93e-2)" "unprognostic (1.16e-1)" "unprognostic (1.71e-2)" "unprognostic (1.92e-2)" "unprognostic (7.28e-3)" "unprognostic (1.70e-3)" "unprognostic (1.71e-1)" "unprognostic (2.85e-2)" "unprognostic (1.45e-1)" "unprognostic (3.56e-2)" "prognostic unfavorable (3.73e-5)" "unprognostic (1.03e-1)" "unprognostic (2.27e-1)" "unprognostic (5.75e-2)" "unprognostic (1.45e-1)" 358.3 153.9 486.0 158.7 470.8 121.9 717.3 495.6 726.7 218.6 452.3 322.8 312.8 73.5 653.7 667.7 85.8 129.7 515.4 493.0 498.5 536.2 971.1 236.0 182.9 499.4 495.1 86.0 143.8 866.9 76.9 116.3 510.0 451.5 297.3 116.3 369.9 215.1 273.0 451.0 229.6 97.2 512.7 115.5 185.1 201.3 487.6 173.3 133.7 460.5 324.5 136.5 327.7 516.4 543.0 276.9 557.1 257.2 1339.7 1131.9 350.7 281.3 708.7 387.0 746.1 580.6 427.8 747.3 312.1 440.6 938.5 277.9 397.0 588.3 345.9 498.2 262.1 641.4 279.9 775.8 335.6 206.1 2479.2 648.2 376.5 596.2 222.1 255.4 464.3 358.8 77.0 679.2 558.8 559.1 436.5 585.9 370.2 349.7 429.7 157.4 541.4 658.5 948.1 816.5 263.2 210.1 235.3 548.5 634.9 388.8 338.0 952.8 332.5 259.3 329.8 288.8 346.3 220.9 170.5 610.0 365.7 364.8 315.3 1180.7 439.9 1077.9 472.9 489.1 347.3 461.4 367.8 465.2 748.8 505.3 279.1 419.2 285.8 450.7 402.5 791.0 615.7 792.2 486.0 470.8 495.6 726.7 493.0 498.5 499.4 495.1 510.0 512.7 487.6 516.4 505.2 150.6 613.0 46.0 256.7 289.2 249.4 724.2 190.1 37.9 806.5 1025.9 1079.6 663.4 390.0 310.8 14.6 796.5 395.6 737.5 1197.4 466.9 844.4 154.8 194.7 206.2 371.3 108.8 5.2 670.3 643.2 258.2 243.1 185.6 433.4 219.4 167.8 2215.1 1069.4 30.3 3.9 495.0 524.9 305.0 785.7 325.7 152.2 476.1 1058.3 15.0 871.5 928.6 552.0 33.2 25.0 372.7 612.0 127.5 192.0 355.0 753.6 2834.8 340.5 59.1 151.2 267.2 289.9 462.0 30.1 972.6 684.9 516.3 260.8 456.0 673.2 361.0 DBP DABP ENSG00000105516 "D-box binding PAR bZIP transcription factor" Q10586 19 48630030-48637379 "Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 318.3;Horizontal cells: 215.4;Muller glia cells: 194.2;Rod photoreceptor cells: 108.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 61.7;NB-4: 235.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.49e-1)" "unprognostic (3.68e-3)" "unprognostic (2.16e-3)" "unprognostic (1.40e-1)" "unprognostic (4.67e-2)" "prognostic favorable (5.49e-4)" "unprognostic (2.00e-1)" "prognostic favorable (1.16e-5)" "unprognostic (3.32e-2)" "unprognostic (2.39e-1)" "unprognostic (4.24e-3)" "unprognostic (4.75e-2)" "prognostic favorable (2.41e-5)" "unprognostic (2.23e-1)" "unprognostic (2.52e-1)" "unprognostic (1.46e-2)" "unprognostic (3.61e-2)" 12.4 53.0 22.5 6.6 34.6 7.5 12.6 35.7 32.9 12.9 9.7 18.7 19.2 13.2 7.2 21.1 11.6 6.0 18.3 21.9 23.4 17.9 24.7 9.8 14.6 21.3 24.5 33.5 14.0 15.6 34.9 2.8 18.6 16.8 3.8 32.6 42.2 13.8 57.1 58.1 15.5 4.5 23.5 19.1 16.4 16.4 29.0 13.6 34.4 7.7 8.4 8.8 16.3 20.5 4.3 7.3 3.6 17.6 2.6 3.4 3.8 1.0 9.8 3.0 7.4 4.6 39.7 8.5 4.8 4.8 3.6 9.8 12.6 2.5 2.5 8.9 6.0 17.2 6.1 2.4 12.9 10.6 12.5 12.1 2.3 0.5 2.0 21.1 0.6 17.9 1.3 61.7 2.7 5.9 32.8 235.3 2.5 11.3 4.9 15.8 2.9 22.2 1.5 1.3 11.7 14.7 5.5 26.5 15.6 1.6 4.8 10.5 1.1 6.5 17.8 3.4 1.9 28.4 50.7 15.6 3.1 15.0 3.9 3.3 3.0 4.9 1.9 3.5 3.9 2.7 3.2 1.6 4.1 1.7 2.5 3.1 0.1 0.7 1.9 3.5 3.7 1.1 22.5 34.6 35.7 32.9 21.9 23.4 21.3 24.5 18.6 23.5 29.0 20.5 14.1 12.8 6.2 9.4 21.7 21.9 15.3 3.1 52.3 318.3 17.2 23.5 4.7 12.8 3.2 7.3 87.6 5.2 15.9 8.0 45.0 5.8 1.4 9.0 25.4 10.8 1.8 6.9 4.2 5.6 1.9 25.5 7.1 13.1 0.0 17.6 10.4 10.0 10.9 215.4 5.7 8.1 6.1 15.1 9.6 3.3 16.8 19.4 17.8 1.9 12.9 194.2 32.0 1.5 4.8 3.0 11.3 25.6 6.8 7.8 63.7 26.6 1.3 108.4 0.0 22.8 13.6 1.3 8.4 32.2 22.6 1.6 20.8 85.8 7.5 18.3 DCDC1 "DCDC5, FLJ46154" ENSG00000170959 "Doublecortin domain containing 1" M0R2J8 11 30830369-31369810 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.5;choroid plexus: 10.6" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 20.9;Early spermatids: 39.0;Endometrial ciliated cells: 47.7;Late spermatids: 18.0;Respiratory ciliated cells: 61.6;Rod photoreceptor cells: 19.0;Spermatocytes: 15.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/70: 1.5" "Low region specificity" "Detected in all" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (1.01e-2)" "unprognostic (1.57e-1)" "unprognostic (8.72e-2)" "unprognostic (1.55e-2)" "unprognostic (9.78e-2)" "unprognostic (1.87e-2)" "unprognostic (1.06e-2)" "unprognostic (5.68e-2)" "unprognostic (4.73e-1)" "unprognostic (3.17e-1)" "unprognostic (4.47e-3)" "unprognostic (6.84e-2)" "unprognostic (1.28e-1)" "unprognostic (1.31e-2)" "unprognostic (1.81e-1)" "unprognostic (2.09e-3)" "unprognostic (2.61e-1)" 0.0 0.1 0.9 0.0 1.0 0.0 0.3 0.3 0.4 0.4 10.6 0.0 0.0 0.2 1.7 0.0 4.1 1.8 0.0 2.4 1.3 0.9 2.7 0.4 0.0 4.5 4.5 0.2 1.0 1.1 1.8 0.0 2.7 0.0 0.0 3.6 0.1 0.1 0.0 0.2 0.0 0.0 3.4 0.0 0.0 2.4 1.7 0.0 0.7 0.1 0.0 0.0 0.0 1.3 0.0 0.3 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.7 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 1.5 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.0 0.3 0.4 2.4 1.3 4.5 4.5 2.7 3.4 1.7 1.3 0.2 0.0 1.5 3.3 0.1 0.3 0.3 0.9 0.0 6.0 0.8 0.9 1.0 2.8 4.8 0.0 20.9 0.0 0.0 0.0 0.0 0.9 39.0 47.7 0.8 0.2 0.0 0.0 5.3 0.0 0.0 0.7 0.0 1.7 0.0 0.3 0.0 3.4 0.1 0.0 1.9 0.0 2.0 0.6 0.3 18.0 1.5 0.1 0.0 1.0 0.0 4.6 0.0 1.5 1.4 0.0 0.0 0.4 0.0 0.2 0.0 1.2 61.6 19.0 0.0 0.1 0.7 15.4 4.4 0.0 0.0 0.0 0.1 0.4 0.0 0.1 DDC AADC ENSG00000132437 "Dopa decarboxylase" P20711 7 50458436-50565405 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine biosynthesis" "Decarboxylase, Lyase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 165.8;kidney: 314.9;retina: 175.6" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 410.3;Proximal enterocytes: 391.5;Proximal tubular cells: 429.5;Rod photoreceptor cells: 498.9" "Group enriched" "Detected in many" 5 "colorectal cancer: 23.5;liver cancer: 13.4;pancreatic cancer: 6.4;renal cancer: 18.7;stomach cancer: 9.9" "Group enriched" "Detected in many" 9 "midbrain: 86.3;pons: 29.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "CACO-2: 54.5;Hep G2: 49.3;OE19: 83.6;SCLC-21H: 130.9;SH-SY5Y: 135.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "midbrain: 74.5;pons: 29.4" HPA017742 Enhanced Approved "Actin filaments" NA NA 120000 "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Actin filaments" "HPA017742: AB_1847832" "unprognostic (1.04e-1)" "unprognostic (3.68e-2)" "unprognostic (2.57e-2)" "unprognostic (3.49e-5)" "unprognostic (1.17e-1)" "unprognostic (1.03e-1)" "unprognostic (1.28e-1)" "unprognostic (5.15e-2)" "unprognostic (4.69e-2)" "unprognostic (5.44e-2)" "unprognostic (9.36e-3)" "unprognostic (5.24e-2)" "unprognostic (1.76e-3)" "unprognostic (1.60e-1)" "unprognostic (3.55e-1)" "unprognostic (7.65e-2)" "unprognostic (1.16e-1)" 0.5 48.9 0.1 2.3 0.7 0.0 1.0 0.0 0.6 0.0 0.2 36.5 154.8 0.0 9.1 0.1 0.0 0.1 0.0 0.2 2.2 314.9 54.6 2.0 0.1 6.1 86.3 0.8 15.8 0.0 0.0 0.0 29.4 0.6 37.5 175.6 0.0 0.0 0.0 0.1 165.8 1.7 0.0 0.1 18.1 1.5 1.9 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 1.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 54.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.3 0.0 0.0 11.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 83.6 0.0 0.0 0.0 0.7 1.3 0.0 130.9 135.9 0.0 4.4 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.6 0.2 2.2 6.1 86.3 29.4 0.0 1.9 0.2 0.0 0.0 12.2 0.0 2.5 0.0 0.0 0.0 0.0 89.3 0.1 0.1 0.4 2.8 0.6 3.7 41.7 0.0 0.0 34.4 25.4 0.1 6.6 0.1 0.0 1.8 410.3 0.0 0.3 0.9 0.1 0.1 0.0 0.4 0.0 0.0 1.1 67.2 0.1 3.3 0.4 67.8 0.0 1.3 0.0 5.4 0.0 2.5 0.0 0.0 0.0 45.1 0.0 0.0 0.1 0.2 31.8 0.0 0.0 0.3 391.5 429.5 0.0 498.9 0.0 0.0 0.0 4.0 0.4 0.0 0.0 0.1 1.3 0.1 88.7 0.2 DHRSX "DHRS5X, DHRS5Y, DHRSXY, DHRSY, SDR46C1, SDR7C6" ENSG00000169084 "Dehydrogenase/reductase X-linked" Q8N5I4 X 2219506-2502805 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA003035, HPA075955" Approved Uncertain "Mitotic spindle,Cytosol" "Secreted to blood" Yes NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 1: Pancreatic cells - Digestion" Cytosol "Mitotic spindle" "HPA003035: AB_1080631, HPA075955: " "unprognostic (7.77e-2)" "unprognostic (1.06e-1)" "unprognostic (3.95e-2)" "unprognostic (4.65e-3)" "unprognostic (8.87e-2)" "unprognostic (1.78e-1)" "unprognostic (1.29e-1)" "unprognostic (4.59e-3)" "unprognostic (1.08e-1)" "unprognostic (1.21e-1)" "unprognostic (1.08e-2)" "unprognostic (1.17e-1)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (1.57e-1)" "unprognostic (2.11e-1)" "unprognostic (3.69e-2)" 13.1 16.2 7.0 4.8 8.2 5.2 12.2 6.7 7.7 13.3 11.9 12.7 6.5 13.0 8.0 6.0 11.0 8.8 19.9 6.1 6.8 14.7 30.6 10.3 5.6 11.5 10.1 12.6 21.9 11.5 10.6 8.2 8.4 13.2 8.3 2.2 14.7 7.0 12.4 9.0 10.8 6.9 8.5 10.1 16.5 6.4 10.9 6.1 13.3 7.0 3.9 11.2 9.3 8.2 8.1 35.7 23.9 11.0 28.8 18.0 18.5 17.8 29.9 13.3 17.9 26.9 16.8 12.6 22.6 21.5 31.4 3.9 16.4 14.3 9.4 24.1 26.1 12.2 17.9 21.2 33.8 6.6 9.5 22.3 17.7 11.6 11.4 22.7 10.9 13.9 14.0 6.1 21.7 9.2 28.5 9.7 6.9 10.6 9.9 10.4 12.4 3.5 14.5 19.3 24.3 22.9 17.0 20.3 14.2 14.8 8.7 10.8 15.6 14.5 3.6 8.4 10.6 7.1 0.1 33.2 9.7 8.7 6.7 14.9 38.3 34.6 15.1 30.6 16.0 25.0 13.5 12.7 35.1 20.1 12.3 10.6 56.4 17.7 19.5 28.3 18.2 21.0 7.0 8.2 6.7 7.7 6.1 6.8 11.5 10.1 8.4 8.5 10.9 8.2 8.7 19.2 9.3 64.3 19.2 10.6 22.9 58.0 20.5 9.5 19.3 16.9 23.4 25.8 24.4 25.8 10.4 42.9 17.0 32.9 13.7 52.3 0.6 16.1 15.9 14.8 19.2 13.7 41.2 81.2 43.5 26.9 21.4 14.4 17.8 27.1 15.0 50.6 38.4 3.3 42.7 21.4 32.6 20.8 30.7 3.0 24.2 26.3 12.4 61.8 35.9 9.4 14.4 46.3 31.9 71.0 28.8 25.2 29.1 65.3 49.2 43.7 14.8 6.2 19.7 12.0 18.3 12.0 21.2 11.3 6.5 107.3 14.0 14.6 24.1 29.2 DHX58 "D11LGP2, LGP2" ENSG00000108771 "DExH-box helicase 58" Q96C10 17 42101404-42112714 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "monocytes: 39.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 45.5;BJ hTERT+ SV40 Large T+ RasG12V: 52.9;SK-MEL-30: 27.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018670, HPA019570" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 3: Monocytes - Immune response regulation" "Golgi apparatus, Cytosol" Nucleoplasm "HPA018670: AB_1847665, HPA019570: AB_1847666" "prognostic favorable (3.45e-4)" "unprognostic (1.03e-2)" "unprognostic (3.56e-3)" "unprognostic (1.54e-2)" "unprognostic (2.45e-2)" "unprognostic (4.82e-2)" "unprognostic (2.05e-3)" "unprognostic (5.45e-2)" "unprognostic (1.18e-1)" "unprognostic (1.15e-1)" "unprognostic (6.02e-2)" "unprognostic (3.72e-1)" "unprognostic (1.27e-2)" "unprognostic (8.65e-2)" "unprognostic (8.01e-2)" "unprognostic (2.31e-1)" "unprognostic (4.31e-3)" 8.9 11.9 5.5 10.2 6.1 12.3 7.6 4.7 7.4 7.7 4.9 7.0 8.5 7.0 5.9 6.4 11.5 12.1 4.9 4.6 4.8 7.3 14.5 11.8 12.5 6.9 5.4 11.9 6.0 7.2 6.9 7.0 6.2 8.7 5.1 0.6 18.6 8.2 3.7 7.5 8.5 7.3 7.5 18.4 9.3 10.8 5.4 12.5 5.5 4.3 7.4 8.0 5.9 6.7 2.5 0.0 0.1 1.3 11.3 9.9 0.3 3.3 22.4 45.5 52.9 0.3 14.6 0.2 3.4 5.4 10.2 2.0 0.2 3.5 1.7 9.3 0.3 3.9 2.6 0.9 12.6 3.6 8.6 15.9 5.9 4.0 3.9 8.0 5.5 23.5 0.0 12.8 2.5 0.0 21.7 4.5 0.4 0.6 0.0 7.8 0.0 1.2 5.2 8.6 0.4 0.0 1.5 5.9 27.0 0.0 7.9 3.8 2.4 2.3 0.1 0.8 1.1 4.3 3.8 0.2 4.6 3.3 2.6 2.3 7.7 6.9 3.1 9.7 4.8 4.6 4.7 2.9 5.9 3.5 5.1 3.8 3.2 6.8 8.6 2.0 4.4 5.0 5.5 6.1 4.7 7.4 4.6 4.8 6.9 5.4 6.2 7.5 5.4 6.7 9.1 9.6 3.4 6.8 4.8 1.5 3.9 6.2 3.4 1.0 3.5 3.7 1.7 8.6 7.6 7.3 0.0 4.0 4.7 2.3 1.9 7.0 9.0 4.5 2.9 7.0 0.0 0.4 1.9 6.9 4.6 4.1 3.6 4.0 1.3 7.5 3.3 14.0 9.8 0.0 2.4 3.2 4.1 7.0 0.7 12.1 8.7 7.4 3.6 8.4 39.9 2.4 2.1 4.0 1.8 5.7 4.3 9.1 1.3 5.4 3.9 5.7 11.6 0.6 0.0 3.7 3.8 18.1 1.0 2.3 1.6 0.8 6.6 8.2 1.9 2.9 DIPK2B "CXorf36, DIA1R, FLJ14103" ENSG00000147113 "Divergent protein kinase domain 2B" Q9H7Y0 X 45148373-45200901 "Disease related genes, Predicted secreted proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Adipocytes: 96.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 57 "HUVEC TERT2: 81.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002806 Uncertain "Secreted - unknown location" NA NA 940000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA002806: AB_1078595" "unprognostic (2.12e-1)" "unprognostic (1.32e-2)" "unprognostic (8.51e-3)" "unprognostic (2.05e-1)" "unprognostic (4.65e-2)" "unprognostic (4.07e-3)" "unprognostic (7.30e-2)" "unprognostic (1.61e-1)" "unprognostic (1.50e-1)" "unprognostic (3.39e-1)" "unprognostic (6.06e-2)" "unprognostic (1.32e-1)" "unprognostic (1.75e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (8.47e-2)" "unprognostic (3.11e-2)" 40.8 5.3 14.4 6.1 15.0 0.8 36.9 11.7 13.9 19.6 7.8 9.1 2.6 20.5 6.9 6.5 18.0 8.8 27.3 11.4 13.1 7.0 1.4 14.1 5.7 14.4 14.2 6.9 3.5 4.6 3.3 40.5 14.1 11.3 3.8 1.4 6.8 7.2 16.6 7.4 7.7 20.7 12.4 3.1 6.3 1.5 14.8 2.7 18.5 16.6 3.4 14.3 13.9 15.4 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 81.7 0.1 0.0 0.5 0.0 0.1 0.0 0.3 0.1 1.4 0.5 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.5 0.1 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 14.4 15.0 11.7 13.9 11.4 13.1 14.4 14.2 14.1 12.4 14.8 15.4 96.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 DIRAS3 "ARHI, NOEY2" ENSG00000162595 "DIRAS family GTPase 3" O95661 1 68045886-68051631 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 143.9;ovary: 60.1;pituitary gland: 52.5" "Group enriched" "Detected in many" 5 "Distal tubular cells: 64.6;Theca cells: 206.2" "Group enriched" "Detected in many" 4 "endometrial cancer: 4.3;glioma: 16.3;pancreatic cancer: 5.6;thyroid cancer: 13.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 8.2;HSkMC: 17.2;TIME: 11.2;U-251 MG: 9.1;U-87 MG: 16.9" "Low region specificity" "Detected in all" "HPA028483, HPA028557, HPA029384" Approved Approved "Nuclear membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "Nuclear membrane, Cytosol" "HPA028483: AB_10599599, HPA028557: AB_10602091, HPA029384: AB_10601343" "prognostic favorable (9.21e-4)" "unprognostic (3.45e-1)" "unprognostic (3.17e-2)" "unprognostic (1.69e-2)" "unprognostic (1.15e-2)" "unprognostic (2.84e-1)" "unprognostic (1.58e-1)" "unprognostic (2.31e-2)" "unprognostic (1.13e-1)" "unprognostic (7.86e-2)" "unprognostic (8.35e-2)" "unprognostic (4.33e-1)" "prognostic favorable (9.21e-4)" "unprognostic (1.34e-1)" "unprognostic (4.99e-1)" "unprognostic (1.24e-2)" "unprognostic (5.07e-3)" 1.4 20.1 25.3 0.5 18.7 0.1 5.0 2.2 11.5 5.2 3.0 3.3 7.5 2.5 10.6 1.7 3.3 10.2 11.3 7.0 143.9 6.9 9.5 5.1 0.2 39.6 49.2 60.1 20.0 7.5 52.5 0.6 18.5 2.9 0.8 4.0 2.3 2.6 1.1 2.1 1.4 1.2 7.8 2.5 4.2 5.5 104.7 1.6 3.8 1.9 0.3 3.1 6.4 8.0 0.0 1.5 1.6 0.0 5.2 3.9 0.6 4.6 1.6 0.3 1.2 0.0 0.8 0.0 0.2 4.8 0.1 0.2 0.2 0.0 0.3 0.0 0.2 0.0 0.6 0.0 8.2 0.0 0.0 17.2 0.1 0.7 0.0 0.0 1.0 0.2 0.3 0.0 5.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.2 0.0 0.1 0.5 0.1 0.0 11.2 0.0 0.5 0.2 9.1 2.7 0.0 0.0 16.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 25.3 18.7 2.2 11.5 7.0 143.9 39.6 49.2 18.5 7.8 104.7 8.0 0.3 0.0 1.8 5.2 0.0 3.2 25.0 0.6 0.6 1.1 5.4 6.5 5.9 7.2 2.5 3.7 10.4 1.1 0.0 0.4 64.6 3.7 0.1 0.7 0.7 1.7 16.2 0.0 2.2 18.7 0.1 10.3 4.1 1.8 0.0 0.8 3.3 3.9 0.1 0.0 8.8 2.3 0.0 0.0 4.8 0.8 6.8 0.3 5.4 0.0 0.0 0.7 1.0 5.0 0.2 2.9 0.1 1.5 0.0 5.3 0.1 11.1 0.9 6.1 0.0 16.9 1.7 0.0 1.4 1.7 2.8 0.4 0.7 206.2 0.7 2.4 DNAH2 "DNHD3, FLJ46675, KIAA1503" ENSG00000183914 "Dynein axonemal heavy chain 2" Q9P225 17 7717354-7833744 "Predicted intracellular proteins, Predicted membrane proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 13.1;parathyroid gland: 10.5;retina: 21.1" "Group enriched" "Detected in many" 4 "Respiratory ciliated cells: 43.0;Rod photoreceptor cells: 123.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 2.6;CACO-2: 4.0;CAPAN-2: 2.4;OE19: 1.8;SCLC-21H: 2.3;SiHa: 2.3" "Low region specificity" "Detected in some" HPA067103 Enhanced Approved Microtubules NA NA "Cluster 77: Retina - Visual perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" Microtubules "HPA067103: AB_2685778" "unprognostic (2.03e-2)" "unprognostic (1.79e-2)" "unprognostic (2.23e-2)" "unprognostic (1.25e-1)" "unprognostic (3.92e-2)" "unprognostic (2.51e-1)" "unprognostic (1.35e-1)" "unprognostic (7.50e-3)" "unprognostic (1.29e-2)" "unprognostic (8.28e-2)" "unprognostic (2.51e-3)" "unprognostic (1.74e-1)" "unprognostic (2.06e-2)" "unprognostic (1.22e-1)" "unprognostic (2.33e-1)" "unprognostic (8.74e-3)" "unprognostic (4.60e-2)" 0.4 0.1 1.5 0.1 2.4 0.5 0.5 1.0 1.1 1.2 7.1 0.2 0.2 0.5 1.6 0.1 13.1 0.4 0.1 1.8 1.1 0.1 0.4 1.9 0.1 5.6 6.8 2.5 0.5 10.5 0.4 1.7 2.8 0.3 0.2 21.1 0.1 0.0 0.1 0.2 0.1 0.2 3.5 0.2 0.2 6.5 1.1 0.3 0.3 0.0 0.1 0.2 0.1 1.8 2.6 0.1 0.1 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 4.0 2.4 0.1 1.1 0.0 0.0 0.2 0.0 0.6 0.0 0.1 0.1 0.0 0.3 0.1 0.6 0.1 0.1 0.2 0.0 0.4 0.0 0.3 0.0 0.1 0.1 0.2 0.0 0.5 0.1 0.2 0.2 1.8 0.8 0.1 0.2 0.0 0.0 0.7 2.3 0.1 2.3 0.0 1.2 0.2 0.2 0.1 0.1 0.2 0.4 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.6 0.1 0.0 0.1 0.0 0.0 1.5 2.4 1.0 1.1 1.8 1.1 5.6 6.8 2.8 3.5 1.1 1.8 1.1 0.0 1.1 1.3 0.7 0.3 1.0 1.7 0.0 2.7 0.6 1.0 1.9 0.0 3.6 0.0 2.1 0.0 0.0 0.0 0.0 0.4 6.2 20.2 0.6 1.2 6.7 0.0 6.1 0.0 0.0 0.8 0.0 0.8 0.0 2.3 0.4 0.1 0.1 1.7 4.9 0.5 8.2 0.3 0.7 2.3 0.3 0.2 0.0 1.0 0.0 4.6 0.0 3.0 2.1 0.1 1.1 0.0 0.0 0.7 0.0 0.4 43.0 123.9 0.0 1.0 1.0 9.6 2.6 0.0 0.1 0.0 0.2 0.5 0.2 0.9 DNAH6 "Dnahc6, DNHL1, FLJ37357, HL-2" ENSG00000115423 "Dynein axonemal heavy chain 6" Q9C0G6 2 84516455-84819589 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.6;choroid plexus: 12.1;fallopian tube: 5.4" "Cell type enhanced" "Detected in many" "Early spermatids: 77.5;Endometrial ciliated cells: 98.2;Excitatory neurons: 94.2;Respiratory ciliated cells: 143.6" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "OE19: 1.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA036391, HPA061401" Enhanced NA NA "Cluster 32: T-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "HPA036391: AB_10672220, HPA061401: " "unprognostic (4.87e-2)" "unprognostic (4.60e-2)" "unprognostic (1.04e-1)" "unprognostic (1.40e-2)" "unprognostic (1.42e-1)" "unprognostic (9.72e-2)" "unprognostic (1.67e-1)" "unprognostic (6.43e-2)" "unprognostic (6.06e-2)" "unprognostic (3.46e-1)" "unprognostic (8.11e-8)" "unprognostic (2.04e-1)" "unprognostic (2.33e-1)" "unprognostic (2.11e-2)" "unprognostic (1.87e-1)" "unprognostic (1.80e-2)" "unprognostic (5.97e-2)" 0.3 0.2 1.4 0.1 2.4 0.0 0.4 0.0 1.7 0.2 12.1 0.1 0.0 0.5 1.2 0.0 5.4 0.1 0.0 1.5 1.1 0.4 1.1 0.8 0.1 4.4 4.6 0.3 0.2 1.6 0.4 0.0 2.4 0.1 0.2 0.8 0.0 0.2 0.0 0.0 0.1 0.1 2.7 0.0 0.5 2.7 1.6 0.5 1.2 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.1 1.4 2.4 0.0 1.7 1.5 1.1 4.4 4.6 2.4 2.7 1.6 1.6 0.6 6.4 4.1 18.6 0.6 0.1 2.2 5.4 0.0 0.8 1.4 1.8 1.2 1.5 13.7 0.0 2.1 0.9 0.3 0.3 0.0 0.3 77.5 98.2 1.5 0.9 0.0 0.4 94.2 0.9 0.2 2.7 4.1 3.0 0.0 1.6 0.0 6.9 0.1 0.0 28.2 1.0 10.2 0.3 0.2 25.0 0.6 0.3 1.8 9.4 0.0 2.0 0.0 5.5 13.7 0.3 0.3 0.7 0.1 1.0 0.2 1.0 143.6 4.8 0.0 2.1 1.7 23.3 5.1 0.0 0.0 0.3 1.3 0.3 1.1 0.3 DNASE1L3 "DNAS1L3, LSD" ENSG00000163687 "Deoxyribonuclease 1 like 3" Q13609 3 58192257-58214697 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Necrosis" "Endonuclease, Hydrolase, Nuclease" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "liver: 271.4;lymphoid tissue: 263.5" "Cell type enriched" "Detected in many" 6 "Hepatic stellate cells: 1670.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 424.7" "Lineage enriched" "Detected in many" 20 "dendritic cells: 424.7" "Cell line enhanced" "Detected in some" "BEWO: 1.9;Karpas-707: 1.1;RPMI-8226: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA019955 Approved "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA019955: AB_1847805" "unprognostic (7.49e-3)" "unprognostic (3.08e-3)" "unprognostic (9.75e-3)" "unprognostic (3.92e-3)" "unprognostic (2.93e-3)" "unprognostic (1.01e-2)" "prognostic favorable (1.20e-6)" "unprognostic (4.74e-4)" "unprognostic (2.10e-1)" "unprognostic (9.71e-2)" "unprognostic (1.91e-3)" "unprognostic (6.95e-2)" "prognostic favorable (1.06e-7)" "unprognostic (7.57e-2)" "unprognostic (2.47e-1)" "unprognostic (1.57e-1)" "unprognostic (5.64e-3)" 20.6 41.0 0.6 38.0 0.5 2.9 10.3 1.5 0.7 4.4 5.4 31.4 29.7 1.7 1.5 16.9 2.8 7.9 14.7 0.6 0.5 47.7 271.4 18.0 38.7 0.6 0.5 1.1 1.1 1.7 20.3 7.1 0.8 1.8 42.2 0.5 8.7 1.4 1.0 4.5 42.5 3.5 0.5 263.5 5.9 3.8 0.8 22.6 16.5 0.3 54.0 12.0 9.4 1.2 0.0 0.2 0.1 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.7 0.0 0.3 0.1 0.0 0.3 0.0 0.1 0.0 0.7 0.0 0.2 1.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 2.1 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.3 0.2 0.2 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.3 0.2 20.4 0.1 0.1 40.4 20.7 0.1 0.0 0.6 0.5 0.2 424.7 0.0 3.4 0.6 0.5 1.5 0.7 0.6 0.5 0.6 0.5 0.8 0.5 0.8 1.2 126.6 0.0 9.8 0.3 25.7 9.2 0.3 1.1 12.0 0.1 0.9 1.4 1.2 35.8 2.0 0.0 0.0 0.1 76.3 0.5 3.9 0.0 1.9 0.4 0.2 239.9 0.0 85.5 0.1 0.4 1.2 6.1 0.0 0.8 1.3 0.1 1670.9 27.1 0.5 1.7 0.1 0.2 0.0 127.1 144.3 3.2 4.1 18.6 3.6 0.0 35.3 0.0 0.0 0.0 0.0 0.0 0.0 25.6 0.2 0.3 0.1 3.3 0.0 0.2 0.0 0.3 1.3 0.3 0.2 59.3 16.3 0.3 3.8 2.6 0.0 1.0 DNMT3L MGC1090 ENSG00000142182 "DNA methyltransferase 3 like" Q9UJW3 21 44246339-44262216 "Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "liver: 1.9" "Group enriched" "Detected in some" 6 "Hepatocytes: 20.8;Proximal tubular cells: 29.1" "Cancer enriched" "Detected in some" 90 "testis cancer: 46.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "BEWO: 24.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA055234, HPA066780" Approved Approved "Nuclear speckles" NA NA "Cluster 15: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA055234: AB_2682750, HPA066780: AB_2685719" "unprognostic (1.05e-4)" "unprognostic (1.91e-1)" "unprognostic (2.73e-9)" "unprognostic (2.77e-1)" "unprognostic (5.28e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.6 1.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 24.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.7 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 20.8 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 29.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.1 DPP4 "ADCP2, CD26, DPPIV" ENSG00000197635 "Dipeptidyl peptidase 4" P27487 2 161992245-162074394 "CD markers, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Aminopeptidase, Hydrolase, Protease, Receptor, Serine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 137.9;parathyroid gland: 155.7;placenta: 134.1;prostate: 107.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 140.3;Proximal enterocytes: 291.1;Proximal tubular cells: 101.4;Syncytiotrophoblasts: 172.0" "Cancer enhanced" "Detected in all" "prostate cancer: 55.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 52.3" "Lineage enriched" "Detected in many" 10 "T-cells: 52.3" "Cell line enhanced" "Detected in many" "ASC diff: 194.4;ASC TERT1: 212.6;BJ hTERT+: 207.0;RPTEC TERT1: 263.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB045970, HPA068778, HPA071236" Enhanced "Secreted to blood" NA NA 190000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB045970: AB_11140529, HPA068778: , HPA071236: " "unprognostic (4.47e-2)" "unprognostic (4.47e-2)" "unprognostic (8.89e-2)" "unprognostic (3.36e-1)" "unprognostic (7.25e-2)" "unprognostic (5.40e-2)" "unprognostic (2.78e-1)" "unprognostic (3.54e-2)" "unprognostic (3.58e-1)" "unprognostic (4.73e-1)" "unprognostic (2.36e-1)" "prognostic unfavorable (1.98e-4)" "prognostic favorable (1.35e-6)" "unprognostic (4.68e-2)" "unprognostic (6.33e-2)" "prognostic favorable (4.99e-4)" "unprognostic (1.21e-2)" 13.3 3.1 0.2 5.3 0.2 0.6 8.4 0.1 0.6 10.9 0.1 14.6 107.0 3.6 4.0 3.0 7.4 6.7 3.4 0.2 0.1 94.9 57.2 16.0 5.8 0.2 0.2 3.5 3.5 155.7 0.1 134.1 0.3 107.3 16.9 0.1 84.5 23.5 1.5 5.7 137.9 3.0 0.1 11.2 7.6 1.3 0.8 12.4 5.0 3.9 4.4 5.7 3.5 0.4 0.2 0.2 1.0 0.0 194.4 212.6 0.6 37.7 207.0 10.9 37.2 38.0 1.0 0.0 13.6 71.0 30.2 1.1 0.4 0.0 6.2 12.3 0.0 0.0 0.0 57.1 77.0 0.0 0.0 22.0 0.1 66.3 0.5 9.1 6.6 0.7 0.0 0.0 3.6 0.0 3.6 0.5 2.0 1.3 72.7 0.0 0.0 0.6 263.3 0.0 0.1 0.4 0.0 0.0 0.0 4.4 0.0 0.3 37.0 21.8 1.1 0.7 0.0 0.0 0.0 0.0 22.5 0.0 0.0 0.0 0.0 0.0 6.6 0.0 52.3 0.2 16.2 10.7 1.2 0.0 15.7 6.6 0.4 5.3 0.0 4.0 2.0 4.7 0.2 0.2 0.1 0.6 0.2 0.1 0.2 0.2 0.3 0.1 0.8 0.4 10.8 6.4 26.0 0.3 2.1 4.1 0.4 0.1 0.0 1.8 0.2 0.8 3.3 12.8 2.8 14.7 10.4 140.3 10.4 27.4 1.9 3.0 15.0 2.3 7.1 9.4 55.2 0.4 31.6 0.0 59.1 35.3 2.0 68.0 13.9 5.3 9.3 34.5 14.5 0.0 6.3 16.4 0.0 0.9 7.6 7.9 0.0 4.8 5.4 3.7 1.1 0.0 1.0 2.5 0.7 1.4 23.8 0.0 2.1 32.7 291.1 101.4 2.2 0.1 0.0 2.1 1.5 4.0 1.1 0.1 4.1 172.0 25.8 29.2 29.1 0.3 DPPA4 FLJ10713 ENSG00000121570 "Developmental pluripotency associated 4" Q7L190 3 109326141-109337572 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.7;lymphoid tissue: 12.2;testis: 4.1" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 22.3;Erythroid cells: 16.4;Extravillous trophoblasts: 17.2;Spermatogonia: 11.7;Syncytiotrophoblasts: 6.2" "Cancer enriched" "Detected in single" 218 "testis cancer: 59.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 7.3" "Lineage enriched" "Detected in single" 12 "dendritic cells: 7.3" "Group enriched" "Detected in some" 4 "HAP1: 89.7;NTERA-2: 327.5;SuSa: 120.7" "Not detected" "Not detected" "Not detected" "Not detected" "CAB020678, HPA035249, HPA035250" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome,Cytosol" Yes NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 5: NTERA-2 - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome, Cytosol" "CAB020678: , HPA035249: AB_2674535, HPA035250: AB_2674536" "unprognostic (2.07e-2)" "unprognostic (2.53e-2)" "unprognostic (3.80e-1)" "unprognostic (2.53e-1)" "unprognostic (8.57e-2)" "unprognostic (1.80e-2)" "unprognostic (1.67e-1)" "unprognostic (1.52e-1)" "unprognostic (9.83e-2)" "unprognostic (2.02e-2)" "unprognostic (6.60e-2)" "unprognostic (2.48e-2)" "unprognostic (3.03e-8)" "unprognostic (5.28e-2)" "unprognostic (5.04e-2)" "unprognostic (5.56e-2)" "unprognostic (3.85e-2)" 0.0 0.0 0.0 0.1 0.0 4.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.7 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.1 0.0 12.2 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 43.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 89.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 327.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 120.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.1 0.0 0.5 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 22.3 4.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 16.4 0.1 0.0 17.2 0.5 0.0 0.0 1.3 0.0 0.4 1.6 1.7 0.0 0.1 0.0 0.0 0.3 0.0 0.6 0.3 0.4 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 0.7 0.0 0.0 0.9 0.3 0.3 11.7 0.0 0.0 6.2 0.5 0.2 0.0 0.3 DPT ENSG00000143196 Dermatopontin Q07507 1 168695468-168729206 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 424.7" "Group enriched" "Detected in many" 5 "Fibroblasts: 457.5;Leydig cells: 231.8;Peritubular cells: 123.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "ASC diff: 143.3;fHDF/TERT166: 59.9" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "midbrain: 1.0" HPA065548 Approved Vesicles "Secreted to extracellular matrix" NA NA 610000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA065548: AB_2685511" "unprognostic (1.49e-1)" "unprognostic (7.62e-2)" "unprognostic (5.66e-2)" "unprognostic (4.39e-2)" "unprognostic (4.64e-2)" "unprognostic (3.78e-3)" "unprognostic (4.09e-2)" "unprognostic (2.57e-1)" "unprognostic (1.48e-1)" "unprognostic (1.03e-2)" "unprognostic (8.88e-2)" "unprognostic (2.16e-2)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.12e-3)" "unprognostic (2.89e-2)" "unprognostic (1.09e-1)" "unprognostic (8.98e-3)" 334.6 39.6 0.4 28.6 0.5 0.0 251.3 0.5 1.0 177.6 0.5 424.7 18.8 63.2 60.8 86.0 129.1 78.0 241.4 0.5 0.4 13.2 29.0 48.6 58.6 0.5 0.4 30.3 84.8 4.9 2.1 37.5 0.6 55.2 58.2 0.0 72.0 52.7 37.1 39.2 94.2 138.5 0.5 0.9 108.5 15.4 0.5 48.0 75.0 209.3 70.1 103.3 166.9 0.7 0.0 0.0 0.0 0.0 143.3 0.6 0.2 0.1 6.7 7.2 7.4 0.0 0.0 0.0 0.0 59.9 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 4.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 7.6 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.5 1.0 0.5 0.4 0.5 0.4 0.6 0.5 0.5 0.7 18.7 3.2 1.7 0.3 0.3 31.9 0.1 0.0 1.8 0.0 2.2 2.3 7.4 0.0 0.6 0.0 0.0 0.6 0.4 0.1 0.0 0.1 1.2 0.3 10.7 6.9 0.0 0.0 4.8 0.2 0.8 457.5 3.1 0.2 0.0 0.0 8.9 0.0 0.6 0.0 3.4 0.0 0.0 0.0 45.6 4.4 231.8 4.0 39.2 1.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 123.8 0.5 0.5 0.0 0.1 0.0 0.0 0.0 24.4 18.5 0.5 0.3 3.1 32.0 0.4 5.0 2.2 0.0 0.6 DPYD DPD ENSG00000188641 "Dihydropyrimidine dehydrogenase" Q12882 1 97077743-97995000 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 68.5" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 1712.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033241, HPA045210" Uncertain NA NA 1600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "CAB033241: AB_2094323, HPA045210: AB_2679256" "unprognostic (2.33e-2)" "unprognostic (1.69e-1)" "unprognostic (9.82e-3)" "unprognostic (1.04e-1)" "unprognostic (1.13e-2)" "unprognostic (8.81e-2)" "unprognostic (2.86e-1)" "unprognostic (3.05e-1)" "unprognostic (1.56e-1)" "unprognostic (9.29e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (6.54e-2)" "unprognostic (5.32e-2)" "unprognostic (1.43e-1)" "unprognostic (3.43e-2)" "unprognostic (3.71e-1)" "unprognostic (2.25e-1)" 22.2 13.2 7.2 22.6 12.8 10.3 16.7 5.7 10.4 18.8 2.4 11.9 21.9 14.9 8.4 17.1 14.3 25.7 8.9 7.4 12.9 12.6 68.5 29.6 16.6 12.4 9.4 24.0 11.8 9.2 6.2 4.5 12.1 9.9 10.1 3.3 15.0 13.4 5.8 7.1 19.4 18.2 6.9 24.7 8.4 3.7 12.9 17.0 10.3 10.1 12.0 18.2 14.2 24.4 22.2 6.2 7.8 0.2 42.4 72.5 0.1 35.2 31.9 32.1 23.6 0.0 9.2 11.7 50.6 32.9 5.1 5.2 0.0 8.3 58.7 11.6 7.3 10.0 11.1 0.2 18.8 4.5 0.6 57.5 3.0 25.7 29.3 67.7 26.8 6.8 0.4 36.4 17.0 0.0 23.6 6.4 0.9 0.2 7.5 0.1 37.1 18.6 39.4 0.1 11.1 8.8 30.1 2.5 0.3 0.8 0.0 10.2 30.9 69.2 5.0 56.4 70.6 3.0 0.1 0.2 10.2 12.6 56.2 18.2 61.1 4.1 11.6 29.5 14.8 2.2 13.3 11.0 32.7 4.9 12.5 11.1 59.8 13.3 27.1 0.9 15.8 21.9 7.2 12.8 5.7 10.4 7.4 12.9 12.4 9.4 12.1 6.9 12.9 24.4 25.5 16.0 39.1 23.8 15.4 7.6 8.8 9.4 18.8 2.5 8.4 8.3 5.3 40.0 11.5 7.3 0.0 0.2 19.2 3.3 5.9 2.5 7.0 1.5 15.2 14.7 3.0 13.3 258.6 6.4 0.2 30.0 10.7 1.7 9.5 4.5 17.2 54.2 17.1 0.0 30.5 5.5 6.1 130.4 27.0 4.0 33.5 73.7 3.6 105.9 98.1 4.8 27.8 34.2 1712.3 5.3 2.1 18.8 17.0 4.9 21.0 6.6 8.6 0.1 13.1 16.0 17.7 1.2 3.1 19.7 5.5 0.1 31.4 5.1 6.8 9.3 DZIP1 "DZIP, KIAA0996" ENSG00000134874 "DAZ interacting zinc finger protein 1" Q86YF9 13 95578202-95644706 "Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 384.1;Late spermatids: 774.5;Spermatocytes: 222.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054891, HPA057272" Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 43: Testis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Centrosome" "HPA054891: AB_2682631, HPA057272: AB_2683390" "unprognostic (6.74e-3)" "unprognostic (7.65e-2)" "unprognostic (1.94e-1)" "unprognostic (4.64e-3)" "unprognostic (4.82e-2)" "unprognostic (5.52e-3)" "unprognostic (6.34e-2)" "unprognostic (2.49e-1)" "unprognostic (3.34e-2)" "unprognostic (8.63e-2)" "unprognostic (1.17e-2)" "unprognostic (1.67e-1)" "unprognostic (1.36e-2)" "unprognostic (2.41e-3)" "unprognostic (1.48e-1)" "unprognostic (3.64e-2)" "unprognostic (3.89e-3)" 5.0 3.4 8.6 2.5 8.5 0.1 4.4 6.9 9.4 12.4 5.7 10.7 1.0 12.6 7.2 3.2 12.4 5.1 4.3 7.7 8.7 11.4 1.1 4.6 2.2 7.0 8.1 16.3 9.9 0.4 10.3 2.5 6.1 6.4 1.8 4.0 2.3 6.2 1.3 1.6 4.0 6.1 5.6 1.5 4.7 14.8 11.5 0.8 2.4 2.1 1.7 7.9 7.1 7.1 1.1 4.2 17.5 15.5 14.5 16.2 3.6 11.0 13.2 12.7 15.2 0.2 0.0 0.0 2.5 9.4 5.5 0.0 11.7 3.8 14.8 1.1 9.6 15.6 4.4 11.0 9.2 0.1 0.0 11.7 0.4 4.2 5.8 23.1 9.1 1.1 0.0 0.1 11.4 0.0 0.0 0.0 8.6 0.0 0.4 0.0 10.1 0.0 15.4 1.8 4.2 9.9 8.3 0.0 0.6 22.4 0.0 7.3 1.3 12.3 5.3 1.8 8.8 0.0 0.0 0.0 3.5 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.6 8.5 6.9 9.4 7.7 8.7 7.0 8.1 6.1 5.6 11.5 7.1 2.4 0.0 0.0 63.6 0.0 0.6 1.1 3.1 4.6 18.7 0.6 3.4 3.5 2.8 3.9 1.8 4.2 4.5 0.0 0.0 7.9 20.8 384.1 37.2 34.1 2.5 0.0 0.0 86.8 0.2 2.6 19.0 0.5 2.7 0.0 3.1 2.9 0.4 0.7 6.7 95.7 0.0 4.1 0.3 1.5 774.5 38.8 1.2 3.6 19.7 2.0 8.3 0.0 106.6 5.1 0.6 0.0 43.6 0.0 0.8 0.0 24.4 19.4 1.5 19.7 18.2 15.8 222.8 12.6 1.2 1.0 1.8 0.5 20.8 0.0 0.3 ECH1 HPXEL ENSG00000104823 "Enoyl-CoA hydratase 1" Q13011 19 38815422-38831841 "Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 749.9;skeletal muscle: 906.9" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 796.9;Proximal tubular cells: 880.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002907, HPA005835" Supported Supported Supported Mitochondria No No 720000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA002907: AB_1847964, HPA005835: AB_1847965" "unprognostic (1.91e-1)" "unprognostic (3.03e-2)" "unprognostic (3.64e-2)" "unprognostic (6.43e-2)" "unprognostic (5.73e-3)" "unprognostic (6.90e-2)" "unprognostic (1.28e-1)" "unprognostic (1.79e-1)" "unprognostic (2.43e-1)" "unprognostic (5.86e-2)" "unprognostic (2.24e-1)" "unprognostic (3.37e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (2.23e-4)" "unprognostic (3.54e-1)" "unprognostic (3.52e-1)" "unprognostic (1.74e-2)" 216.0 343.0 51.2 47.6 53.7 62.3 194.2 54.1 60.3 124.9 58.6 232.9 93.5 115.3 32.3 168.4 114.0 66.8 749.9 49.3 52.5 271.6 556.1 122.1 67.8 51.8 51.8 107.2 141.4 56.0 77.1 67.1 53.4 99.5 99.9 12.8 138.6 43.3 906.9 149.0 167.4 59.7 50.6 192.3 180.5 100.7 55.0 51.0 117.9 455.1 65.7 142.4 132.4 53.3 64.0 273.8 42.0 68.8 161.0 82.0 61.8 31.7 53.2 26.6 27.1 178.8 124.8 98.6 117.2 72.8 24.1 30.1 70.9 72.9 21.1 345.3 37.7 120.7 76.5 146.1 161.3 131.9 116.9 109.0 186.6 35.1 61.2 52.3 63.4 127.3 58.4 160.8 59.6 120.0 91.8 82.2 27.8 278.8 65.9 101.8 126.2 199.0 168.7 142.6 51.4 67.2 161.0 77.1 86.5 27.3 106.4 288.4 53.7 45.5 39.3 46.5 29.6 121.0 153.2 96.4 71.4 164.9 90.7 316.1 312.9 268.0 253.6 248.2 237.2 368.4 243.5 249.1 308.6 361.3 216.5 242.4 41.6 342.7 212.8 221.5 391.8 541.8 51.2 53.7 54.1 60.3 49.3 52.5 51.8 51.8 53.4 50.6 55.0 53.3 125.4 86.6 104.7 13.1 111.1 82.2 220.0 320.8 80.8 22.4 124.0 143.8 302.7 205.9 203.2 145.3 16.7 796.9 103.4 257.7 510.6 195.4 64.5 95.7 56.9 96.4 189.2 99.9 7.1 90.1 370.6 104.1 112.7 77.0 120.9 177.6 90.7 549.4 277.6 37.0 8.6 298.9 193.3 99.0 85.2 56.7 130.8 97.5 145.9 8.4 205.1 53.0 113.3 7.1 16.0 97.0 257.5 143.0 122.1 100.1 383.0 880.0 182.6 21.4 78.9 88.4 119.7 73.3 51.3 121.6 90.8 580.9 118.6 624.2 350.0 218.1 ECHDC3 FLJ20909 ENSG00000134463 "Enoyl-CoA hydratase domain containing 3" Q96DC8 10 11742366-11764070 "Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 161.6;skeletal muscle: 128.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 81.2;Distal tubular cells: 144.8;Hepatocytes: 152.0;Proximal tubular cells: 209.9" "Cancer enhanced" "Detected in all" "liver cancer: 35.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "eosinophil: 15.4" "Lineage enriched" "Detected in many" 9 "granulocytes: 15.4" "Cell line enhanced" "Detected in many" "A-431: 52.9;BEWO: 28.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA038306 Enhanced NA NA 120000 "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 28: BEWO - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA038306: AB_10672586" "unprognostic (8.74e-2)" "unprognostic (1.69e-1)" "unprognostic (2.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.92e-1)" "unprognostic (2.37e-2)" "unprognostic (1.09e-1)" "unprognostic (1.64e-1)" "unprognostic (5.07e-1)" "unprognostic (2.23e-1)" "unprognostic (2.04e-2)" "unprognostic (3.53e-1)" "prognostic favorable (3.43e-4)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (3.91e-4)" 71.7 29.3 2.6 3.2 2.4 7.0 52.8 2.5 2.5 15.9 17.5 6.7 1.8 11.0 2.2 22.9 11.1 1.8 67.0 2.6 4.3 63.0 161.6 17.5 3.7 3.0 2.7 10.5 29.7 1.8 10.8 7.9 2.9 13.7 3.6 2.0 28.6 13.7 128.4 21.7 6.0 4.4 2.9 15.7 26.6 14.3 3.8 2.8 17.9 60.1 5.5 9.3 17.8 3.3 52.9 7.6 0.1 0.0 0.0 0.0 28.7 6.3 0.0 4.6 4.0 19.1 0.4 0.0 5.8 14.1 1.3 12.5 11.9 1.9 2.0 0.1 0.5 0.0 7.6 0.0 20.5 0.0 7.4 14.1 11.8 4.8 0.0 0.4 9.3 0.0 19.6 0.0 1.4 7.3 0.0 0.2 13.3 0.1 0.0 16.3 0.0 0.0 3.6 0.0 5.5 8.4 0.0 13.1 0.0 16.5 20.5 2.6 2.8 0.0 5.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 3.6 2.9 1.7 15.4 0.0 0.6 0.0 0.2 0.1 0.5 1.7 1.7 0.3 0.0 3.6 0.5 0.7 0.6 0.0 0.3 2.6 2.4 2.5 2.5 2.6 4.3 3.0 2.7 2.9 2.9 3.8 3.3 2.7 19.2 11.8 0.0 3.6 4.5 13.8 2.7 0.0 0.9 16.7 27.2 42.2 17.2 6.4 16.5 2.1 81.2 0.1 1.3 144.8 33.6 4.0 2.3 5.9 3.5 0.0 1.7 0.3 29.8 32.9 6.0 16.3 4.6 0.0 49.5 4.6 152.0 13.1 0.0 0.2 0.6 6.1 14.1 2.2 6.3 2.8 10.6 8.8 1.0 6.8 13.1 0.0 0.0 0.5 13.6 1.2 3.4 6.4 26.1 0.9 209.9 0.4 2.7 19.7 12.0 12.0 22.1 9.6 0.4 5.7 28.9 1.5 4.9 1.9 6.8 EDNRA "ET-A, ETA-R, hET-AR" ENSG00000151617 "Endothelin receptor type A" P25101 4 147480917-147544954 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 113.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 117.1;Leydig cells: 43.8;Peritubular cells: 68.1;Sertoli cells: 52.6;Smooth muscle cells: 108.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 9.4;ASC TERT1: 18.2;HHSteC: 9.3;LHCN-M2: 22.7;SH-SY5Y: 16.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013774, CAB018957" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "CAB018957: AB_2039838, HPA013774: AB_1847994" "unprognostic (3.08e-2)" "unprognostic (6.28e-2)" "unprognostic (1.78e-1)" "unprognostic (3.42e-1)" "unprognostic (1.07e-2)" "unprognostic (1.39e-1)" "unprognostic (3.20e-2)" "unprognostic (7.20e-2)" "unprognostic (2.75e-3)" "unprognostic (1.47e-2)" "unprognostic (1.34e-3)" "unprognostic (2.88e-1)" "prognostic unfavorable (1.50e-7)" "prognostic unfavorable (3.93e-4)" "unprognostic (6.20e-3)" "unprognostic (3.11e-2)" "unprognostic (2.53e-3)" 14.0 5.5 2.1 3.3 2.8 0.0 8.3 2.7 4.2 57.0 2.1 3.2 3.4 44.7 23.3 4.4 18.4 12.7 26.0 2.2 2.2 4.2 3.1 22.7 3.8 2.9 3.1 37.5 1.1 3.4 2.8 12.1 2.9 30.7 3.4 0.3 6.4 113.9 4.0 4.6 2.9 45.1 2.5 8.4 5.4 6.2 2.9 4.9 6.8 5.5 2.6 11.8 24.0 3.0 0.0 1.2 5.2 0.0 9.4 18.2 0.0 2.9 3.8 0.4 0.1 0.2 0.0 0.0 0.0 0.9 0.6 0.0 0.4 0.7 0.2 0.0 1.9 0.0 2.8 0.0 9.3 0.0 0.0 6.9 0.6 0.5 0.0 3.4 0.0 0.0 0.0 1.4 22.7 0.3 0.0 0.1 1.5 0.0 1.1 0.0 0.9 0.1 1.3 1.0 0.0 16.3 0.0 0.0 0.0 3.4 0.0 0.0 0.0 3.6 0.7 0.0 0.0 1.3 0.4 0.0 7.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.8 2.7 4.2 2.2 2.2 2.9 3.1 2.9 2.5 2.9 3.0 7.7 3.2 5.3 1.0 0.0 3.1 0.8 1.7 27.3 0.1 0.8 5.2 24.9 0.0 4.5 0.0 0.0 0.2 0.1 0.0 0.0 0.1 2.9 3.4 117.1 8.0 0.0 0.0 5.3 0.0 0.1 15.9 0.0 2.7 0.0 14.3 0.0 0.0 0.6 0.0 22.5 0.0 0.0 0.0 3.9 3.5 43.8 0.8 3.6 9.4 0.0 0.1 0.0 2.0 1.0 0.2 0.0 68.1 0.0 1.4 0.0 0.5 0.0 0.5 52.6 0.6 108.6 0.7 0.7 7.1 2.7 0.1 0.9 0.3 0.0 0.4 EFCC1 "C3orf73, CCDC48, FLJ12057" ENSG00000114654 "EF-hand and coiled-coil domain containing 1" Q9HA90 3 129001629-129040742 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 5.6" "Cell type enhanced" "Detected in some" "Adipocytes: 7.1;Endothelial cells: 6.5;Enteroendocrine cells: 9.5;Fibroblasts: 10.7;Microglial cells: 9.4;Peritubular cells: 7.5;Sertoli cells: 6.6;Theca cells: 22.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "AF22: 1.3;HL-60: 3.7;U-266/84: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042798, HPA050888" Uncertain NA NA "Cluster 14: B-cells - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 52: Non-specific - Transcription" "HPA042798: AB_2678173, HPA050888: AB_2681263" "unprognostic (1.74e-1)" "unprognostic (5.16e-3)" "unprognostic (1.65e-1)" "unprognostic (1.49e-3)" "unprognostic (1.95e-1)" "unprognostic (2.54e-2)" "unprognostic (1.66e-3)" "unprognostic (7.23e-3)" "unprognostic (1.57e-2)" "unprognostic (2.04e-1)" "prognostic favorable (9.70e-4)" "unprognostic (7.79e-2)" "unprognostic (2.26e-1)" "unprognostic (1.29e-1)" "unprognostic (2.71e-1)" "unprognostic (1.82e-1)" "unprognostic (2.20e-1)" 1.7 0.4 0.8 0.4 0.2 0.1 1.8 1.8 1.0 1.2 0.0 3.5 1.9 1.9 0.1 0.9 1.6 0.5 2.3 2.2 1.4 1.2 0.5 5.6 0.1 1.7 1.0 3.4 0.5 0.1 1.3 0.3 1.8 2.0 0.4 0.0 0.7 0.2 1.0 1.1 2.5 0.1 0.5 2.7 2.1 0.4 1.1 0.2 2.2 0.5 0.0 2.0 1.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 1.8 1.0 2.2 1.4 1.7 1.0 1.8 0.5 1.1 0.0 7.1 0.0 1.1 0.3 0.2 0.3 0.0 0.0 0.0 0.0 1.3 1.0 1.5 0.0 0.0 0.0 0.0 0.1 0.7 0.1 0.0 0.1 1.4 0.2 0.3 6.5 9.5 3.6 1.3 0.6 0.0 10.7 0.0 0.2 0.0 0.4 3.6 0.0 0.1 0.0 0.4 0.0 0.0 0.3 0.8 5.3 4.7 0.1 1.8 9.4 0.0 0.0 2.1 0.0 0.1 0.1 0.0 7.5 0.0 0.1 0.0 0.2 0.0 0.0 6.6 1.1 2.4 0.2 0.4 0.0 0.4 0.1 0.3 22.0 0.2 0.1 EFNB1 "CFNS, Elk-L, EPLG2, LERK2" ENSG00000090776 "Ephrin B1" P98172 X 68829021-68842160 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 117.3;Granulosa cells: 134.5;Hepatic stellate cells: 143.5;Suprabasal keratinocytes: 120.5;Theca cells: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 97.0;hTCEpi: 74.1;PC-3: 70.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031489, HPA067188" Uncertain Supported "Plasma membrane" NA NA 1300000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "CAB031489: AB_631414, HPA067188: AB_2685799" "unprognostic (2.00e-1)" "unprognostic (1.33e-2)" "unprognostic (1.77e-2)" "prognostic unfavorable (3.32e-5)" "unprognostic (1.04e-1)" "unprognostic (2.48e-2)" "unprognostic (8.05e-3)" "unprognostic (2.15e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (3.94e-2)" "prognostic unfavorable (4.29e-4)" "unprognostic (1.29e-1)" "unprognostic (2.17e-3)" "unprognostic (2.76e-2)" "unprognostic (8.03e-2)" "unprognostic (1.72e-3)" "unprognostic (1.86e-2)" 47.0 23.7 9.3 8.2 9.5 2.3 41.2 8.7 11.8 27.1 8.7 27.6 19.1 19.4 10.7 32.0 19.6 18.3 32.5 9.1 8.9 44.0 11.6 41.6 4.3 9.4 9.1 14.3 7.6 16.5 10.3 25.4 8.9 19.8 13.2 1.2 11.2 16.2 9.1 52.5 20.6 8.8 9.6 26.1 18.1 6.3 9.7 5.6 19.6 9.5 4.8 25.9 27.9 9.3 10.4 5.3 41.9 15.6 21.7 13.4 21.9 8.7 9.5 3.8 2.8 4.8 19.0 2.5 56.7 3.3 5.0 54.3 40.0 97.0 2.1 4.3 10.2 2.6 2.3 8.5 20.0 1.9 21.3 25.0 74.1 9.4 42.4 3.4 29.3 5.3 2.8 0.2 3.3 8.5 4.2 2.0 29.0 63.5 70.9 18.6 4.4 16.6 15.9 36.1 15.6 7.5 6.7 2.0 2.6 31.7 1.6 3.6 49.7 7.2 8.9 19.6 3.3 0.1 2.3 2.5 3.6 11.3 4.7 0.0 0.6 0.3 0.4 1.7 0.3 0.3 0.4 0.4 3.5 0.2 0.3 0.2 0.1 0.7 1.1 0.5 0.2 0.5 9.3 9.5 8.7 11.8 9.1 8.9 9.4 9.1 8.9 9.6 9.7 9.3 81.1 3.2 1.1 2.6 3.2 117.3 66.2 60.7 93.4 3.3 3.6 11.2 8.2 20.0 12.8 22.0 0.0 11.4 5.9 59.4 0.0 16.4 0.4 2.6 7.6 42.4 8.4 2.7 1.0 15.6 75.9 20.5 21.4 4.5 4.5 134.5 143.5 4.8 12.4 1.7 1.0 27.6 8.2 9.1 23.8 1.3 27.4 8.6 21.4 2.8 5.9 12.5 2.1 0.5 0.6 46.3 52.6 8.2 2.3 40.2 28.6 5.7 2.8 1.3 13.1 8.7 12.5 2.0 3.8 76.2 120.5 11.2 4.7 116.2 29.8 93.6 EFNB2 "EPLG5, Htk-L, HTKL, LERK5, MGC126226, MGC126227, MGC126228" ENSG00000125266 "Ephrin B2" P52799 13 106489745-106535662 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 239.7;Hepatic stellate cells: 187.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 76.5;OE19: 45.5;SH-SY5Y: 42.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008999, CAB009368" Supported Supported Nucleoplasm,Cytosol NA NA 940000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "CAB009368: AB_2095700, HPA008999: AB_1078721" "unprognostic (1.70e-1)" "unprognostic (1.95e-3)" "unprognostic (1.72e-1)" "unprognostic (5.22e-3)" "unprognostic (4.52e-3)" "prognostic unfavorable (3.11e-6)" "unprognostic (2.32e-2)" "prognostic unfavorable (8.43e-4)" "unprognostic (2.09e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (8.70e-5)" "unprognostic (1.60e-1)" "unprognostic (1.09e-2)" "unprognostic (1.30e-1)" "unprognostic (3.07e-1)" "unprognostic (4.62e-2)" "unprognostic (2.27e-3)" 20.7 6.1 3.8 4.3 5.9 0.2 17.1 1.3 6.2 11.0 0.0 22.1 7.9 10.2 0.7 12.1 8.8 4.2 15.5 5.5 4.9 11.2 4.8 23.4 3.2 0.1 0.1 7.2 3.9 3.2 6.3 15.4 0.3 12.5 9.9 3.2 14.0 10.6 6.5 17.2 14.4 5.5 0.1 7.4 15.0 5.4 1.6 3.6 11.9 8.0 3.2 6.5 14.1 4.3 23.3 1.8 76.5 0.1 0.2 0.7 0.3 10.8 5.4 8.2 4.7 19.1 28.7 0.0 11.0 2.5 0.6 28.4 2.9 10.9 8.9 0.0 24.3 0.1 6.0 0.0 1.5 6.9 0.6 3.5 19.0 0.4 16.1 4.1 10.4 0.2 0.1 0.0 9.1 3.3 0.2 0.1 4.7 45.5 5.0 21.9 3.3 0.1 11.9 2.5 5.8 42.7 3.6 1.7 0.1 21.4 1.0 0.2 9.6 16.3 0.0 0.5 23.8 0.4 0.0 0.0 34.5 0.4 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 5.9 1.3 6.2 5.5 4.9 0.1 0.1 0.3 0.1 1.6 4.3 239.7 6.4 35.7 38.8 4.4 83.2 52.9 15.4 13.1 10.4 39.8 45.3 8.8 5.7 13.2 25.8 0.0 1.4 8.6 114.6 0.0 6.8 0.4 24.7 69.8 106.5 50.6 0.0 49.3 1.4 3.1 15.4 69.3 42.1 17.8 11.8 187.4 1.3 1.1 6.7 29.7 59.8 26.4 5.8 11.9 1.0 0.3 4.0 32.0 48.7 0.0 89.1 0.0 3.5 13.9 46.3 64.3 0.4 1.0 25.1 15.9 0.2 8.7 3.4 0.0 33.1 22.8 0.7 3.3 41.1 86.0 1.9 7.9 6.4 71.5 72.0 EFNB3 "EPLG8, LERK-8" ENSG00000108947 "Ephrin B3" Q15768 17 7705202-7711372 "Cancer-related genes, Predicted membrane proteins" "Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 11.6;Early spermatids: 9.2;Excitatory neurons: 9.1" "Cancer enhanced" "Detected in many" "glioma: 15.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 53.9;AN3-CA: 32.3;hTERT-RPE1: 32.6;SH-SY5Y: 28.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001623 Approved NA NA 11000 "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA001623: AB_1848026" "unprognostic (5.17e-2)" "unprognostic (7.15e-2)" "unprognostic (6.08e-2)" "prognostic unfavorable (5.52e-4)" "unprognostic (3.27e-1)" "unprognostic (1.62e-2)" "unprognostic (5.63e-2)" "unprognostic (3.61e-1)" "unprognostic (2.64e-2)" "unprognostic (1.14e-1)" "prognostic favorable (8.21e-4)" "unprognostic (3.71e-1)" "unprognostic (1.02e-1)" "unprognostic (1.56e-2)" "unprognostic (3.00e-1)" "unprognostic (8.56e-2)" "unprognostic (2.20e-2)" 3.5 2.0 23.1 0.7 25.8 0.0 3.5 0.1 25.3 7.4 5.6 0.7 0.3 10.3 0.5 2.0 5.5 1.2 1.1 23.0 37.3 1.2 1.7 1.0 0.3 9.2 10.7 4.7 1.2 12.0 5.7 1.2 8.7 2.1 0.6 3.6 1.4 0.5 0.3 5.9 0.9 3.7 5.8 0.1 0.8 3.6 38.2 0.4 0.7 0.1 0.9 1.0 2.4 10.7 0.0 1.0 53.9 32.3 1.0 0.7 0.4 0.6 7.2 4.8 3.1 2.0 3.4 0.0 1.1 2.1 0.3 0.4 13.9 6.9 2.8 0.0 6.8 0.2 0.0 0.1 1.5 0.0 0.0 3.1 1.4 1.5 1.1 32.6 0.3 0.5 0.0 0.0 0.9 5.4 0.0 0.0 4.8 0.0 1.0 0.2 0.1 0.0 7.4 0.7 3.4 28.1 0.0 0.0 1.1 9.4 2.9 0.0 0.1 3.2 10.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.1 25.8 0.1 25.3 23.0 37.3 9.2 10.7 8.7 5.8 38.2 10.7 2.1 0.0 0.0 1.0 0.2 4.1 3.8 4.6 6.8 2.2 5.9 11.6 1.7 1.5 0.9 0.0 0.0 0.3 0.0 0.1 0.0 1.1 9.2 2.5 5.9 1.3 6.7 2.7 9.1 0.2 1.0 4.6 0.0 0.7 1.3 3.3 2.2 0.0 0.4 5.0 6.8 0.3 4.1 0.0 0.4 5.6 4.7 0.2 0.0 1.0 0.0 1.4 0.0 0.5 1.3 0.2 0.0 3.4 0.0 1.6 0.0 0.0 6.0 0.7 0.0 0.0 2.2 0.7 0.7 1.8 2.8 0.3 0.1 1.2 0.0 1.6 EFS "CASS3, EFS1, EFS2, HEFS, SIN" ENSG00000100842 "Embryonal Fyn-associated substrate" O43281 14 23356403-23365752 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 48.9;Squamous epithelial cells: 22.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 73.2;AN3-CA: 39.5;BEWO: 57.7;SH-SY5Y: 66.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001581, HPA001790" Approved Uncertain Nucleoplasm,Cytosol No NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm Cytosol "HPA001581: AB_2666367, HPA001790: " "unprognostic (9.58e-3)" "unprognostic (1.10e-2)" "unprognostic (3.68e-2)" "unprognostic (1.78e-1)" "unprognostic (6.05e-2)" "unprognostic (5.76e-2)" "unprognostic (3.00e-1)" "unprognostic (3.85e-2)" "unprognostic (7.36e-2)" "unprognostic (2.15e-1)" "unprognostic (2.75e-1)" "unprognostic (1.00e-2)" "prognostic unfavorable (4.09e-5)" "unprognostic (3.44e-3)" "unprognostic (1.73e-1)" "unprognostic (2.16e-1)" "unprognostic (1.29e-1)" 19.3 12.6 39.7 5.5 59.6 0.0 22.7 51.7 45.6 47.3 28.0 24.4 3.1 29.2 9.9 44.1 28.6 8.7 15.0 35.6 39.3 10.0 1.8 12.1 3.6 63.0 57.6 41.9 2.2 22.2 8.4 10.4 54.8 36.8 3.3 10.6 26.2 22.5 3.6 59.0 9.6 12.5 44.8 7.6 11.9 5.4 49.9 3.2 17.5 5.1 4.8 25.3 42.9 76.0 4.7 0.0 73.2 39.5 17.1 20.0 57.7 5.3 11.3 2.0 0.9 0.0 0.0 0.0 0.0 30.3 0.3 27.5 0.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 11.6 18.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 28.1 0.0 0.0 0.0 22.6 0.1 0.0 24.1 7.8 66.5 15.1 2.6 0.0 8.7 17.6 0.0 0.0 7.6 0.0 19.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.7 59.6 51.7 45.6 35.6 39.3 63.0 57.6 54.8 44.8 49.9 76.0 2.0 0.0 6.7 17.0 0.0 11.6 11.6 5.6 9.6 5.0 20.3 16.3 0.7 0.0 4.1 0.0 6.2 9.3 0.2 0.0 1.9 0.1 0.9 0.6 18.9 1.8 0.0 0.0 0.2 0.0 14.7 15.7 0.0 0.7 0.0 4.4 1.8 0.0 1.6 0.0 0.3 0.0 0.0 0.0 3.7 0.8 20.2 0.4 7.2 1.9 0.0 9.0 0.0 22.1 48.9 0.0 0.0 13.9 0.1 7.6 0.0 0.3 1.1 9.3 6.6 12.6 8.9 2.2 0.5 22.7 13.4 18.1 0.5 0.3 0.0 7.0 EGFL7 ZNEU1 ENSG00000172889 "EGF like domain multiple 7" Q9UHF1 9 136658856-136672678 "Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 806.1;Endothelial cells: 436.5;Hepatic stellate cells: 511.5;Hofbauer cells: 290.3;Spermatogonia: 179.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.1;eosinophil: 3.5;intermediate monocyte: 6.2;non-classical monocyte: 5.5;plasmacytoid DC: 5.9" "Group enriched" "Detected in many" 20 "dendritic cells: 5.9;granulocytes: 3.5;monocytes: 6.2" "Cell line enhanced" "Detected in many" "EFO-21: 183.9;HUVEC TERT2: 329.0;RPMI-8226: 136.8;TIME: 312.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050716 Approved "Secreted to extracellular matrix" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA050716: AB_2732562" "unprognostic (1.72e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (1.55e-2)" "unprognostic (2.70e-2)" "unprognostic (9.76e-3)" "unprognostic (5.03e-1)" "unprognostic (1.03e-1)" "unprognostic (4.31e-3)" "unprognostic (4.39e-2)" "unprognostic (1.14e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (5.28e-4)" "unprognostic (5.69e-2)" "unprognostic (1.74e-1)" "unprognostic (4.09e-2)" "unprognostic (4.49e-2)" 195.6 50.2 108.8 13.4 90.4 14.4 192.3 85.0 144.3 112.9 74.4 49.1 13.4 104.3 9.8 39.8 98.5 27.4 243.3 89.8 86.5 144.3 56.1 204.2 20.8 102.0 96.9 37.8 28.2 18.5 51.3 181.6 100.9 74.9 3.5 1.0 39.4 13.2 60.5 47.8 51.4 13.4 89.9 191.7 40.7 43.3 111.7 5.6 105.5 25.2 2.9 87.5 86.3 85.2 0.1 45.7 14.6 52.7 1.2 1.0 33.4 12.9 2.3 7.3 2.3 16.2 42.4 0.3 183.9 4.3 11.9 6.5 3.7 8.3 0.3 77.2 14.1 28.8 3.4 1.3 11.4 0.0 40.1 1.5 3.2 3.7 0.0 2.5 329.0 2.1 104.9 0.1 2.5 83.5 0.5 0.7 21.1 64.3 2.6 91.4 5.9 136.8 4.6 1.1 9.3 31.0 6.3 5.9 12.2 4.2 15.5 43.6 312.6 1.8 37.2 4.4 2.5 0.4 0.1 0.5 0.2 0.1 38.4 0.0 2.1 3.5 0.0 6.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.8 0.2 5.5 5.9 0.0 2.4 108.8 90.4 85.0 144.3 89.8 86.5 102.0 96.9 100.9 89.9 111.7 85.2 806.1 0.0 26.5 2.3 6.2 11.9 5.6 5.5 9.6 2.0 5.9 6.7 23.7 5.7 4.2 3.7 0.0 3.1 5.9 1.4 7.9 19.4 2.7 1.4 3.4 436.5 1.2 58.9 15.0 2.0 17.8 18.5 0.5 1.9 20.3 2.0 511.5 20.5 290.3 3.3 10.1 4.6 2.0 24.5 14.2 9.2 8.7 18.7 19.6 102.1 1.2 1.9 0.0 3.5 1.8 5.8 3.7 6.0 4.0 19.1 22.5 25.2 0.2 2.3 13.1 13.0 18.4 18.9 179.8 2.7 9.5 6.0 2.9 4.8 0.5 3.5 EI24 "EPG4, PIG8, TP53I8" ENSG00000149547 "EI24 autophagy associated transmembrane protein" O14681 11 125569280-125584684 "Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 461.9" "Cell type enhanced" "Detected in all" "Hepatocytes: 575.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 760.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047165, HPA051029" Approved Supported "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 36: HEL - Hemostasis" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum, Cytosol" "Golgi apparatus" "HPA047165: AB_2679965, HPA051029: AB_2681317" "unprognostic (2.04e-3)" "unprognostic (2.69e-2)" "unprognostic (1.25e-2)" "unprognostic (3.43e-2)" "unprognostic (1.68e-1)" "unprognostic (2.78e-2)" "unprognostic (5.02e-2)" "unprognostic (6.38e-2)" "unprognostic (6.74e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (9.28e-4)" "unprognostic (3.50e-2)" "unprognostic (1.35e-1)" "unprognostic (4.58e-2)" "unprognostic (8.35e-2)" "unprognostic (2.07e-1)" "unprognostic (3.01e-1)" 53.4 32.6 61.1 36.2 62.5 23.2 72.6 59.7 72.4 51.3 59.8 77.8 49.6 46.2 57.4 80.8 50.8 46.3 55.7 60.2 61.5 61.0 248.4 45.0 28.4 60.2 62.5 42.4 101.8 461.9 30.6 48.5 60.2 49.6 80.4 39.4 75.3 58.0 119.5 70.2 49.3 62.5 62.4 30.5 59.7 33.1 64.4 35.3 40.5 104.6 42.3 78.9 48.4 61.0 156.6 115.6 129.5 160.5 207.7 155.9 162.4 159.6 116.8 104.3 93.4 178.9 303.4 158.0 264.0 146.5 110.8 176.1 199.0 326.8 135.2 42.0 142.6 760.9 77.2 179.9 154.1 170.9 78.4 147.5 292.7 157.4 230.2 102.8 223.9 85.1 351.1 61.1 149.4 113.8 79.0 96.4 173.6 398.3 139.5 113.9 155.4 132.8 177.0 272.4 120.1 116.9 187.1 215.5 63.4 212.3 436.4 165.7 195.2 133.8 93.3 94.7 128.7 39.7 84.8 200.5 58.5 256.1 182.2 4.3 7.0 5.9 7.2 6.7 7.2 8.4 5.7 9.0 10.9 6.3 8.1 6.7 0.8 6.5 4.9 14.5 9.1 5.3 61.1 62.5 59.7 72.4 60.2 61.5 60.2 62.5 60.2 62.4 64.4 61.0 73.5 32.1 38.3 13.4 34.8 120.6 130.3 132.6 120.1 58.9 148.8 100.6 61.9 124.4 69.5 110.3 37.5 166.9 32.4 66.4 144.8 178.6 31.1 34.4 59.3 87.1 98.4 102.7 25.1 181.8 201.2 80.1 87.7 46.5 27.3 76.2 74.6 575.0 110.5 82.4 24.0 115.3 105.8 49.8 96.1 49.7 71.4 40.9 90.7 11.2 40.9 107.1 50.4 13.0 23.0 182.1 67.6 72.2 79.1 270.0 68.5 122.7 43.9 36.9 46.0 60.8 80.1 95.9 112.3 176.3 181.4 140.1 31.0 71.3 135.7 189.4 ELN "SVAS, WBS, WS" ENSG00000049540 Elastin P15502 7 74027789-74069907 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 70.4;Fibroblasts: 115.9;Leydig cells: 110.6;Peritubular cells: 148.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 97.6;BJ: 143.7;fHDF/TERT166: 205.6;U-2197: 817.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010750, HPA018111, HPA056941" Supported Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 2900000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB010750: AB_476930, HPA018111: AB_1848109, HPA056941: AB_2683280" "unprognostic (1.51e-2)" "unprognostic (4.86e-2)" "unprognostic (2.50e-2)" "unprognostic (1.11e-1)" "unprognostic (1.57e-2)" "unprognostic (2.72e-2)" "unprognostic (3.70e-3)" "unprognostic (1.23e-1)" "unprognostic (3.33e-2)" "unprognostic (2.00e-3)" "unprognostic (2.88e-1)" "unprognostic (1.09e-1)" "unprognostic (2.18e-3)" "unprognostic (1.79e-2)" "unprognostic (3.90e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (1.62e-3)" 147.2 21.6 11.6 40.8 14.3 0.1 94.2 19.9 17.6 100.2 24.3 57.6 8.8 73.6 18.4 53.0 70.7 76.7 184.1 13.1 15.3 12.8 13.4 214.1 14.5 15.4 20.1 37.0 90.9 2.8 24.9 58.9 13.8 106.4 11.3 2.8 66.9 35.1 17.9 91.3 40.6 90.0 14.9 40.9 63.2 13.1 14.0 5.1 48.4 16.9 4.5 85.3 84.3 17.9 0.0 2.0 0.8 0.0 97.6 0.6 0.6 143.7 0.1 0.0 0.0 0.6 0.1 0.0 0.0 205.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.7 0.5 0.1 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.6 0.6 8.3 0.8 0.8 0.4 58.0 1.0 0.0 0.0 28.0 68.9 0.0 1.2 0.1 10.0 0.6 0.0 0.0 0.2 0.3 817.9 0.0 0.2 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.6 14.3 19.9 17.6 13.1 15.3 15.4 20.1 13.8 14.9 14.0 17.9 34.6 0.0 6.4 34.9 0.1 11.0 13.5 33.9 4.0 2.8 0.9 1.1 9.7 2.8 4.3 7.3 2.1 0.1 0.3 0.2 0.0 0.3 3.5 3.5 70.4 28.4 1.8 0.0 4.6 3.9 0.3 115.9 7.1 2.3 0.0 0.2 47.2 4.2 0.5 6.7 8.1 1.3 0.0 0.6 20.4 7.5 110.6 1.2 14.2 23.4 0.0 15.9 0.0 14.1 18.5 1.1 0.2 148.2 0.4 1.4 0.0 0.1 3.0 0.8 0.0 12.2 34.1 1.1 1.2 2.1 10.9 0.1 1.2 0.6 0.2 1.1 ELOVL2 Ssc2 ENSG00000197977 "ELOVL fatty acid elongase 2" Q9NXB9 6 10980759-11044305 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 52.5;placenta: 35.3;retina: 27.9" "Cell type enhanced" "Detected in many" "Astrocytes: 95.0;Cone photoreceptor cells: 29.2;Extravillous trophoblasts: 19.7;Sertoli cells: 19.7;Spermatocytes: 23.0" "Group enriched" "Detected in many" 8 "breast cancer: 11.9;glioma: 25.8;liver cancer: 24.0;melanoma: 14.2;prostate cancer: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 29.9;GAMG: 31.2;HBF TERT88: 29.0;Hep G2: 23.4;RH-30: 31.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 15: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 33: Fibroblasts - ECM organization" "prognostic favorable (6.73e-5)" "unprognostic (4.20e-1)" "unprognostic (1.64e-1)" "unprognostic (1.28e-5)" "unprognostic (4.06e-2)" "unprognostic (4.09e-3)" "unprognostic (1.89e-1)" "unprognostic (5.73e-2)" "unprognostic (1.63e-1)" "unprognostic (2.56e-1)" "unprognostic (6.92e-3)" "unprognostic (1.78e-2)" "unprognostic (1.04e-12)" "unprognostic (9.98e-4)" "unprognostic (8.86e-2)" "unprognostic (3.41e-1)" "unprognostic (9.47e-2)" 1.2 0.9 8.6 1.5 10.7 0.0 4.8 10.0 13.9 0.2 4.0 0.5 0.2 0.5 2.3 0.4 0.2 0.6 3.2 9.0 8.8 0.2 52.5 0.2 0.5 10.6 9.3 0.2 2.6 9.7 2.9 35.3 9.8 5.3 0.1 27.9 0.7 0.4 1.0 0.2 0.3 0.7 9.6 0.0 0.1 11.5 8.8 1.1 1.8 0.9 0.9 2.0 0.1 14.1 0.0 5.3 20.1 0.0 0.0 0.0 11.5 0.4 1.0 17.7 29.9 0.0 0.0 0.0 0.0 1.1 31.2 0.0 21.3 0.0 29.0 0.0 18.2 0.1 0.4 23.4 0.9 0.4 4.8 0.2 0.0 13.7 0.0 1.0 0.0 0.9 1.2 0.0 0.4 0.1 12.1 0.2 3.8 0.0 17.4 16.6 31.8 0.0 0.0 0.3 8.0 9.1 0.0 0.0 7.5 16.1 3.7 9.3 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 10.7 10.0 13.9 9.0 8.8 10.6 9.3 9.8 9.6 8.8 14.1 0.5 0.0 0.0 95.0 0.1 0.1 0.0 0.0 0.0 2.2 7.8 1.3 1.2 8.6 0.0 0.0 29.2 2.3 0.0 0.0 0.0 7.2 10.1 0.0 0.5 1.9 0.0 0.0 2.5 1.0 19.7 8.0 0.0 0.0 0.0 0.3 0.0 17.5 1.2 0.0 5.9 0.0 0.0 0.0 0.0 14.9 0.9 0.1 0.0 6.5 0.0 4.9 0.0 4.5 16.8 1.0 0.0 0.4 0.0 1.9 0.0 0.1 0.0 11.8 19.7 0.1 3.9 23.0 8.9 0.2 0.0 1.6 0.1 0.0 0.0 0.1 ELOVL7 FLJ23563 ENSG00000164181 "ELOVL fatty acid elongase 7" A1L3X0 5 60751791-60844274 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglial cells: 190.2;Oligodendrocytes: 90.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.9;neutrophil: 1.3" "Lineage enriched" "Detected in single" 17 "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "GAMG: 41.9;HDLM-2: 29.3;HEL: 37.3" "Low region specificity" "Detected in all" HPA036337 Approved NA NA "Cluster 10: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 44: Endometrium - Transcription" "HPA036337: AB_10670797" "unprognostic (6.34e-2)" "unprognostic (1.96e-2)" "unprognostic (1.51e-2)" "prognostic unfavorable (3.87e-5)" "unprognostic (3.84e-1)" "unprognostic (1.66e-1)" "unprognostic (1.60e-2)" "unprognostic (1.02e-1)" "unprognostic (1.76e-1)" "unprognostic (1.79e-1)" "unprognostic (2.37e-1)" "unprognostic (2.10e-1)" "prognostic favorable (1.54e-9)" "unprognostic (6.95e-2)" "unprognostic (1.01e-3)" "unprognostic (2.94e-1)" "unprognostic (6.30e-3)" 10.5 5.5 23.1 2.2 24.9 1.0 22.1 29.5 26.5 3.6 36.2 8.8 11.8 2.2 0.9 5.0 2.8 19.3 0.9 18.3 30.0 16.2 1.0 3.8 2.5 31.8 26.3 0.5 8.5 21.0 2.7 0.8 32.9 22.0 11.5 10.5 4.7 1.2 0.5 26.2 21.3 3.7 30.1 0.5 3.3 0.8 32.9 1.8 16.8 1.0 4.0 7.6 6.7 32.2 20.7 7.6 0.1 0.5 0.0 0.0 18.6 0.0 4.3 2.5 8.4 9.6 21.4 0.0 9.1 0.0 41.9 1.2 11.9 8.3 3.8 29.3 6.9 37.3 0.9 3.2 0.2 3.0 15.2 0.1 14.6 0.3 12.3 0.9 0.0 6.5 5.9 7.2 0.0 17.8 0.1 0.3 2.4 1.9 0.1 1.6 1.9 1.2 19.4 18.5 7.8 1.2 10.9 8.8 5.0 2.0 14.2 0.6 0.2 1.5 9.0 0.2 7.2 18.5 19.7 0.3 13.2 0.8 0.4 1.9 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 2.5 23.1 24.9 29.5 26.5 18.3 30.0 31.8 26.3 32.9 30.1 32.9 32.2 14.5 12.8 3.1 4.9 0.5 31.1 13.1 1.4 4.6 2.3 3.1 1.4 0.7 20.0 4.8 12.9 0.0 0.2 0.3 8.8 5.9 6.8 0.1 6.5 1.6 21.1 4.8 1.3 29.5 3.1 0.0 2.0 5.6 20.4 12.7 0.4 0.4 0.0 0.1 0.0 26.0 17.0 0.0 0.0 16.6 0.0 0.0 4.9 10.6 190.2 2.0 3.5 0.0 6.0 90.8 7.1 13.3 0.0 0.1 23.4 29.7 8.9 1.7 6.7 0.0 1.0 0.8 0.2 1.1 2.9 38.2 2.9 0.9 0.2 15.9 8.6 ENTPD5 "CD39L4, NTPDase-5, PCPH" ENSG00000187097 "Ectonucleoside triphosphate diphosphohydrolase 5 (inactive)" O75356 14 73958010-74019399 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 107.2;kidney: 95.2;liver: 263.7" "Cell type enhanced" "Detected in all" "Distal enterocytes: 209.3;Hepatocytes: 134.8;Intestinal goblet cells: 77.1;Proximal enterocytes: 87.0" "Group enriched" "Detected in all" 5 "liver cancer: 18.2;prostate cancer: 39.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 18.3;eosinophil: 9.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 18.3" "Cell line enhanced" "Detected in all" "RT4: 57.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002927 Enhanced "Secreted to blood" NA NA 5900000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA002927: AB_1078744" "unprognostic (4.19e-1)" "unprognostic (9.63e-3)" "unprognostic (3.11e-2)" "unprognostic (2.06e-2)" "unprognostic (1.98e-1)" "unprognostic (3.87e-2)" "unprognostic (1.46e-1)" "unprognostic (1.19e-1)" "unprognostic (3.34e-1)" "unprognostic (6.01e-2)" "unprognostic (6.20e-2)" "unprognostic (2.55e-1)" "prognostic favorable (3.95e-5)" "unprognostic (1.25e-1)" "unprognostic (5.06e-2)" "unprognostic (1.76e-1)" "unprognostic (6.92e-3)" 8.2 7.7 5.0 11.4 7.3 8.0 12.4 7.1 6.7 7.3 7.1 94.6 72.1 6.3 7.7 11.3 5.7 12.1 7.7 5.1 6.3 95.2 263.7 6.5 5.5 7.6 7.3 6.7 4.9 7.7 5.0 5.6 7.8 37.7 107.2 9.4 10.7 4.4 15.0 8.1 68.4 9.7 6.5 6.0 42.3 8.6 7.3 4.6 6.1 9.1 5.6 16.9 7.2 9.0 9.5 7.8 8.2 15.1 16.5 15.5 9.4 9.6 7.9 6.4 7.1 5.6 10.9 10.6 4.7 12.8 6.0 10.8 8.5 14.1 7.2 8.8 4.0 7.9 5.7 30.9 15.5 4.7 8.8 12.9 14.0 8.7 18.2 8.8 13.1 17.1 8.8 15.4 9.7 13.6 5.4 5.6 2.5 8.5 15.7 6.0 8.0 5.2 11.4 57.1 5.8 6.0 16.6 12.9 9.2 6.4 18.7 4.1 10.8 12.6 12.7 7.5 7.2 10.1 16.9 8.3 8.0 8.8 11.5 18.3 1.2 9.4 2.5 2.3 1.3 1.4 1.3 1.8 1.7 1.5 2.1 2.1 0.1 0.5 1.4 0.9 1.6 1.3 5.0 7.3 7.1 6.7 5.1 6.3 7.6 7.3 7.8 6.5 7.3 9.0 8.0 16.0 6.7 8.1 4.9 3.7 6.2 8.9 5.2 6.6 15.0 7.9 5.2 10.0 11.3 7.3 4.2 8.2 4.3 209.3 25.4 6.9 19.5 10.0 13.6 7.0 16.2 36.6 5.9 12.9 6.7 7.9 23.0 25.8 1.3 9.6 9.7 134.8 6.2 10.1 8.2 77.1 14.2 9.7 1.9 12.7 2.8 5.2 5.4 11.2 5.4 4.9 8.2 2.0 11.3 9.1 58.4 5.7 3.6 28.5 87.0 63.1 6.4 12.2 13.1 6.0 5.9 27.2 19.1 8.5 3.4 3.3 4.9 10.3 60.9 39.0 ENTPD8 "NTPDase-8, UNQ2492" ENSG00000188833 "Ectonucleoside triphosphate diphosphohydrolase 8" Q5MY95 9 137434364-137441816 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 27.6;liver: 14.5" "Group enriched" "Detected in some" 5 "Distal enterocytes: 194.5;Intestinal goblet cells: 181.0;Paneth cells: 174.3;Proximal enterocytes: 167.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 5.0;OE19: 1.7;RPMI-8226: 5.3;T-47d: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA021509 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" Vesicles "HPA021509: AB_1848185" "unprognostic (3.85e-2)" "unprognostic (8.33e-2)" "unprognostic (2.11e-1)" "unprognostic (1.82e-1)" "unprognostic (1.30e-1)" "unprognostic (1.40e-1)" "unprognostic (6.46e-3)" "unprognostic (8.70e-2)" "unprognostic (3.87e-2)" "unprognostic (8.48e-2)" "unprognostic (1.69e-1)" "unprognostic (2.34e-2)" "unprognostic (1.08e-5)" "prognostic favorable (7.17e-4)" "unprognostic (2.17e-1)" "unprognostic (1.15e-1)" "unprognostic (1.78e-1)" 0.0 0.0 0.0 1.4 0.0 0.4 0.4 0.2 0.2 0.6 0.0 21.3 27.6 0.1 0.0 0.3 0.7 3.7 0.0 0.0 0.0 3.1 14.5 0.1 0.1 0.2 0.1 0.1 3.1 0.1 5.1 0.1 0.0 0.4 11.2 0.0 6.3 0.2 0.0 0.1 27.2 0.1 0.0 0.2 8.9 0.5 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.1 5.0 0.0 0.3 0.0 0.4 0.1 0.0 0.0 0.0 1.0 0.1 0.0 0.4 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 1.7 0.2 0.0 0.0 5.3 0.7 0.0 0.2 0.5 0.1 0.0 0.1 0.4 2.8 0.1 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.0 0.0 1.7 1.5 0.4 11.5 0.3 20.2 0.0 0.0 0.1 194.5 0.0 1.3 0.0 3.0 0.4 0.1 3.6 0.0 0.0 7.5 0.2 0.1 31.6 4.7 0.0 0.1 0.4 10.1 0.1 0.0 0.0 181.0 8.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 174.3 0.0 0.2 0.6 167.3 5.9 1.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.3 0.3 0.1 15.6 1.7 EPS8L1 "DRC3, FLJ20258, MGC23164, MGC4642" ENSG00000131037 "EPS8 like 1" Q8TE68 19 55072020-55087923 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 124.3;skin 1: 59.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 104.1;Gastric mucus-secreting cells: 108.1;Paneth cells: 110.2;Syncytiotrophoblasts: 428.0;Urothelial cells: 189.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 2.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 17.6;BEWO: 58.8;SK-BR-3: 19.6;T-47d: 28.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041851, HPA043545" Uncertain Supported Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA041851: AB_2677706, HPA043545: AB_2678544" "unprognostic (1.91e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (4.44e-4)" "unprognostic (7.18e-2)" "unprognostic (9.33e-2)" "unprognostic (2.54e-2)" "unprognostic (4.61e-2)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" "unprognostic (9.43e-2)" "unprognostic (5.84e-3)" "unprognostic (2.65e-2)" "unprognostic (3.85e-3)" "unprognostic (5.04e-3)" "unprognostic (3.02e-1)" "unprognostic (5.41e-3)" "unprognostic (2.63e-1)" 4.5 0.2 0.0 0.9 0.1 0.1 4.0 0.0 0.1 24.0 0.0 3.5 2.3 1.5 0.0 124.3 14.8 0.9 0.6 0.1 0.0 25.1 0.7 3.9 0.0 0.1 0.1 0.5 5.6 2.1 2.1 5.4 0.1 9.2 0.6 0.0 20.4 2.5 0.5 59.7 2.0 0.0 0.0 0.6 27.0 0.6 0.2 0.1 17.4 0.0 1.6 2.7 37.1 0.2 17.6 0.7 0.6 0.4 0.0 0.0 58.8 1.5 0.1 0.0 0.1 7.6 13.7 0.3 3.4 0.0 0.1 9.7 0.4 2.1 0.0 0.3 1.6 1.3 0.6 0.5 0.2 2.6 10.8 0.0 3.6 0.0 0.0 0.0 0.0 1.2 6.2 0.1 0.0 8.0 0.9 2.6 0.8 12.7 0.0 0.1 0.0 5.4 2.7 3.6 0.2 3.8 1.0 19.6 0.8 0.6 28.9 3.2 1.3 0.0 0.7 0.0 0.0 2.4 3.1 1.6 3.3 0.9 2.0 1.1 0.2 2.3 0.3 0.0 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 1.4 0.3 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.2 4.0 9.6 6.1 0.3 0.8 2.0 28.4 39.5 8.6 0.0 16.3 15.1 2.6 8.6 92.2 31.3 0.0 55.1 4.0 104.1 13.7 20.4 1.6 29.1 6.3 10.7 3.0 0.0 0.1 10.2 26.8 4.7 108.1 41.7 10.2 5.4 10.0 0.1 8.9 0.0 0.1 39.0 24.4 1.9 3.4 4.5 1.2 2.6 21.4 0.0 5.2 0.2 6.2 0.0 0.1 94.5 110.2 0.7 1.0 48.7 12.7 1.1 53.6 0.6 26.3 0.5 21.6 1.6 3.6 6.6 4.0 428.0 2.8 0.3 22.1 189.4 ESAM W117m ENSG00000149564 "Endothelial cell adhesion molecule" Q96AP7 11 124752583-124762290 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 405.9;Endothelial cells: 301.0;Hepatic stellate cells: 138.1;Sertoli cells: 151.2;Smooth muscle cells: 89.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.2;naive B-cell: 7.5" "Group enriched" "Detected in many" 9 "B-cells: 7.5;granulocytes: 8.2;T-cells: 2.2" "Group enriched" "Detected in many" 10 "HEL: 218.8;HUVEC TERT2: 277.9;TIME: 142.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056293, HPA072563" Uncertain Approved "Cell Junctions,Cytosol" NA NA 82000000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Cell Junctions" Cytosol "HPA056293: AB_2683089, HPA072563: " "unprognostic (1.52e-1)" "unprognostic (2.03e-1)" "unprognostic (1.05e-2)" "unprognostic (3.56e-1)" "unprognostic (1.41e-2)" "unprognostic (4.49e-3)" "unprognostic (2.61e-1)" "unprognostic (1.10e-1)" "unprognostic (9.05e-2)" "unprognostic (2.99e-2)" "unprognostic (3.08e-1)" "unprognostic (3.60e-1)" "unprognostic (1.54e-1)" "unprognostic (1.24e-2)" "unprognostic (5.10e-2)" "unprognostic (2.29e-1)" "unprognostic (5.06e-2)" 97.5 17.7 38.4 9.0 37.7 1.9 79.4 38.8 46.9 33.3 30.1 20.0 7.0 36.2 7.8 21.8 34.2 20.0 83.0 35.2 38.7 63.6 11.5 112.5 8.7 40.9 38.9 14.4 13.6 13.2 14.8 106.9 44.0 19.8 7.8 2.5 15.6 15.6 27.1 18.2 20.9 29.4 37.3 17.3 23.4 4.3 45.4 5.4 95.9 49.8 8.3 30.8 30.2 37.8 1.2 1.6 0.4 1.2 0.0 0.3 5.1 0.1 0.1 0.0 0.1 2.7 14.1 1.2 3.2 0.0 0.2 0.0 3.7 0.0 0.0 1.8 1.3 218.8 0.1 8.0 0.6 0.4 3.6 0.0 0.0 0.0 0.0 0.2 277.9 0.1 0.2 5.9 0.5 1.8 0.0 0.0 0.6 20.8 2.1 0.0 1.0 0.9 0.0 2.4 0.2 0.8 0.1 16.1 0.0 7.5 3.3 0.8 142.0 0.4 0.4 0.5 0.0 0.2 0.2 0.2 0.1 0.5 0.4 8.2 0.6 0.0 0.1 0.3 0.0 2.1 1.5 0.1 0.4 7.5 2.2 0.8 6.5 0.0 0.0 0.4 0.4 24.8 38.4 37.7 38.8 46.9 35.2 38.7 40.9 38.9 44.0 37.3 45.4 37.8 405.9 38.5 56.0 2.0 4.5 15.2 0.5 0.2 2.8 18.5 2.5 3.2 11.2 0.0 3.0 14.7 4.2 1.8 2.5 3.5 5.9 7.6 5.0 1.1 1.5 301.0 0.0 5.3 1.5 2.4 18.7 13.8 3.6 1.4 3.8 0.1 138.1 1.7 1.1 0.0 0.4 0.4 0.0 5.3 22.1 26.3 0.9 25.7 12.4 20.6 1.2 0.7 0.0 0.5 0.4 46.5 2.1 0.4 2.8 1.8 0.1 0.1 1.9 1.3 151.2 4.6 89.4 0.1 0.9 0.8 10.9 37.1 2.0 2.4 1.6 2.3 ESPNL FLJ42568 ENSG00000144488 "Espin like" Q6ZVH7 2 238100340-238133287 "Predicted intracellular proteins" Hearing Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.0;intestine: 3.5" "Cell type enhanced" "Detected in some" "B-cells: 1.8;Cardiomyocytes: 2.5;Granulosa cells: 2.0;Muller glia cells: 1.4;Proximal tubular cells: 3.4;Skeletal myocytes: 1.6;Theca cells: 2.2" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 12 "cerebellum: 5.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.8;Daudi: 2.6;fHDF/TERT166: 2.3;HHSteC: 2.6;THP-1: 1.8;U-87 MG: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA055103 Uncertain NA NA "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA055103: AB_2682694" "unprognostic (8.04e-2)" "unprognostic (1.29e-1)" "unprognostic (2.34e-2)" "unprognostic (1.18e-3)" "unprognostic (1.51e-2)" "unprognostic (2.12e-1)" "unprognostic (2.01e-2)" "unprognostic (3.20e-1)" "unprognostic (1.79e-1)" "unprognostic (2.18e-1)" "unprognostic (2.95e-1)" "unprognostic (2.24e-1)" "unprognostic (3.94e-6)" "unprognostic (3.49e-2)" "unprognostic (8.52e-2)" "unprognostic (1.08e-1)" "unprognostic (5.67e-2)" 0.4 0.3 0.4 0.1 0.2 0.0 0.4 5.0 0.2 0.8 0.9 0.8 0.3 1.0 0.0 0.2 1.5 0.1 0.7 0.4 0.3 0.3 1.6 0.2 0.5 0.2 0.3 2.2 0.3 0.0 2.1 0.1 0.4 0.6 0.0 0.0 0.0 0.8 0.2 0.2 3.5 0.4 0.0 1.1 0.2 0.4 0.2 0.3 1.0 0.0 0.2 0.6 0.4 0.3 0.0 0.0 0.0 1.8 0.3 0.6 0.3 1.0 0.4 0.8 0.8 0.0 0.0 2.6 1.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.9 2.6 0.0 0.5 0.9 0.0 0.1 0.0 0.0 0.0 0.8 0.8 0.0 1.0 0.0 0.0 1.1 0.1 0.0 0.0 0.8 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 5.0 0.2 0.4 0.3 0.2 0.3 0.4 0.0 0.2 0.3 0.1 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.6 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.1 0.0 2.0 0.0 0.5 0.1 0.0 0.1 0.4 0.0 0.6 0.0 0.3 0.6 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 1.6 0.3 0.0 0.6 0.0 0.0 0.0 0.4 2.2 0.0 0.0 ESRP1 "FLJ20171, RBM35A" ENSG00000104413 "Epithelial splicing regulatory protein 1" Q6NXG1 8 94641074-94707466 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 107.2;Suprabasal keratinocytes: 79.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 138.3;BEWO: 101.1;CAPAN-2: 140.8;hTCEpi: 226.5;OE19: 142.6;RT4: 99.1;T-47d: 108.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023719, HPA023720, HPA067104" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 27: Mucus-secreting cells - Mucin production" "Nuclear bodies" Nucleoplasm "HPA023719: AB_1856124, HPA023720: AB_1856125, HPA067104: AB_2685779" "prognostic unfavorable (9.28e-4)" "unprognostic (7.12e-2)" "unprognostic (2.75e-2)" "prognostic unfavorable (3.56e-4)" "unprognostic (4.12e-1)" "unprognostic (6.99e-3)" "unprognostic (2.70e-1)" "unprognostic (2.61e-2)" "unprognostic (5.19e-2)" "unprognostic (5.51e-2)" "prognostic unfavorable (2.05e-4)" "unprognostic (4.48e-2)" "prognostic favorable (1.96e-8)" "unprognostic (1.34e-1)" "unprognostic (2.63e-1)" "unprognostic (4.96e-2)" "unprognostic (1.29e-1)" 0.2 0.0 0.0 5.2 0.0 0.0 24.2 0.0 0.0 15.5 0.0 57.1 25.2 3.4 29.6 64.2 21.3 8.5 0.1 0.0 0.0 8.5 0.4 15.8 0.0 0.0 0.1 0.1 42.6 28.4 7.2 12.2 0.0 19.9 62.8 0.0 25.9 10.0 0.1 60.6 22.0 2.5 0.0 0.0 38.6 0.6 0.4 5.2 36.6 0.0 15.3 22.5 28.8 0.0 138.3 0.0 0.0 0.2 0.0 0.0 101.1 0.0 0.0 0.0 0.0 44.6 140.8 0.0 3.8 0.0 0.1 81.6 3.8 70.9 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 226.5 0.0 1.4 0.0 0.0 10.7 0.0 0.0 0.0 67.3 1.9 0.4 12.4 142.6 3.4 0.0 0.0 18.3 17.4 99.1 35.1 0.3 0.0 21.0 14.0 21.4 108.0 0.9 0.0 0.1 0.2 0.1 0.3 12.0 13.8 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.2 38.5 36.7 0.0 0.6 44.6 18.9 30.4 35.9 0.0 29.4 18.0 1.0 21.5 32.4 27.6 0.0 55.1 0.5 76.2 13.7 19.6 12.9 47.1 3.7 0.9 33.1 0.0 2.6 27.5 69.1 0.9 58.1 46.5 1.3 0.0 0.4 0.1 6.0 0.0 0.4 107.2 16.2 0.0 3.2 10.3 0.0 0.5 24.9 0.0 0.6 0.0 0.0 0.5 0.4 21.7 48.1 0.7 1.8 25.1 25.5 0.3 35.0 0.0 0.0 0.0 1.2 0.6 0.9 71.3 79.1 62.1 0.8 0.0 73.9 40.1 ETFA "EMA, GA2, MADD" ENSG00000140374 "Electron transfer flavoprotein subunit alpha" P13804 15 76215353-76311472 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 389.7;tongue: 493.5" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 402.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018990, HPA018993, HPA018996, HPA024089" Enhanced Enhanced Mitochondria NA NA 680000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA018990: AB_1848277, HPA018993: AB_1848275, HPA018996: AB_1848276, HPA024089: AB_1848278" "unprognostic (3.44e-3)" "unprognostic (1.50e-1)" "unprognostic (2.29e-1)" "unprognostic (2.26e-1)" "unprognostic (3.71e-3)" "unprognostic (5.99e-2)" "unprognostic (6.81e-3)" "unprognostic (3.02e-1)" "unprognostic (5.01e-2)" "unprognostic (6.01e-2)" "unprognostic (3.38e-3)" "unprognostic (1.99e-1)" "prognostic favorable (5.04e-8)" "unprognostic (2.87e-1)" "unprognostic (4.90e-2)" "unprognostic (9.22e-2)" "unprognostic (2.90e-2)" 93.0 112.3 33.8 55.0 36.0 63.0 70.4 36.0 54.6 38.7 40.3 131.4 135.6 27.0 30.6 85.1 30.1 44.7 243.0 34.2 37.6 180.0 389.7 39.0 60.9 35.6 35.7 25.6 81.6 71.0 13.9 70.9 36.0 42.2 123.5 34.3 49.3 38.2 300.8 40.1 116.3 65.7 35.5 38.8 67.7 28.4 38.2 54.5 38.7 493.5 65.9 74.0 33.1 36.9 122.4 196.7 128.2 134.8 141.7 149.1 201.0 144.4 166.2 183.0 162.8 175.3 221.3 203.5 141.3 144.3 138.5 304.6 502.7 200.2 211.9 245.8 98.0 222.2 131.4 205.2 114.7 214.5 158.7 112.7 185.9 93.1 153.5 100.0 187.8 64.7 214.1 205.2 190.3 191.2 44.9 178.2 99.9 225.3 58.4 192.8 158.6 272.8 202.1 386.9 133.3 67.2 218.2 492.2 205.0 294.4 254.1 223.4 111.4 178.2 119.5 157.0 177.4 99.0 221.0 255.9 127.8 281.1 128.5 50.0 120.3 82.7 65.4 110.3 61.7 77.3 60.6 67.6 159.4 67.3 48.8 60.1 30.2 122.9 96.1 63.4 95.8 141.9 33.8 36.0 36.0 54.6 34.2 37.6 35.6 35.7 36.0 35.5 38.2 36.9 65.7 57.7 41.6 45.1 54.3 53.4 110.8 151.5 44.9 13.1 47.2 46.4 352.9 65.8 84.5 36.8 22.9 277.4 61.1 250.9 209.4 106.5 11.7 29.5 45.1 51.8 65.4 117.8 26.0 84.1 180.8 66.8 90.2 37.0 38.6 53.1 48.9 348.8 132.3 53.8 31.5 141.6 89.5 79.0 84.5 7.9 59.4 103.0 56.9 28.1 129.0 26.7 85.5 37.2 46.9 92.1 176.2 58.3 87.8 92.4 231.1 402.9 50.2 20.4 46.0 44.0 113.7 66.4 40.5 79.5 57.1 300.2 55.5 123.4 187.3 162.0 ETFDH ETFQO ENSG00000171503 "Electron transfer flavoprotein dehydrogenase" Q16134 4 158672125-158709623 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" Oxidoreductase "Disease variant, FDA approved drug targets, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 196.4;tongue: 186.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 146.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041978 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA041978: AB_10795605" "unprognostic (7.19e-2)" "unprognostic (2.28e-1)" "unprognostic (2.90e-2)" "unprognostic (5.92e-3)" "unprognostic (1.91e-1)" "unprognostic (8.45e-2)" "unprognostic (1.23e-3)" "unprognostic (7.17e-2)" "unprognostic (2.01e-1)" "unprognostic (4.55e-2)" "unprognostic (1.71e-2)" "unprognostic (5.76e-2)" "prognostic favorable (5.76e-10)" "unprognostic (2.51e-1)" "unprognostic (2.07e-1)" "unprognostic (8.85e-3)" "unprognostic (1.74e-1)" 34.6 38.0 13.3 10.7 14.8 9.4 16.0 13.9 15.1 10.2 25.5 32.6 63.7 10.4 8.4 25.0 9.3 11.1 93.3 12.8 14.5 46.5 196.4 9.2 8.7 12.3 13.8 10.8 20.4 32.8 9.8 13.0 12.8 13.7 26.9 15.8 21.8 13.2 111.0 18.7 51.4 14.8 12.5 9.5 26.9 11.2 15.0 9.4 13.2 186.9 14.3 12.9 12.8 15.1 13.2 9.2 12.2 21.4 47.2 28.8 6.6 21.3 19.4 13.9 14.3 3.7 24.6 27.8 4.6 24.1 15.8 13.8 22.1 20.9 19.2 51.5 20.3 26.5 17.3 8.0 20.8 24.0 23.4 26.5 23.8 15.8 12.8 20.8 27.3 20.7 15.6 53.8 22.2 14.7 22.7 11.0 5.0 33.2 19.4 18.4 4.3 21.9 21.2 10.6 18.7 8.0 21.0 39.5 21.8 10.0 30.4 17.6 13.6 11.9 6.7 18.5 12.2 31.3 42.1 20.3 24.6 19.2 13.5 3.7 21.5 41.5 10.1 22.6 12.7 10.3 9.8 10.4 18.3 9.6 11.6 9.9 7.8 10.5 20.9 13.1 16.1 9.5 13.3 14.8 13.9 15.1 12.8 14.5 12.3 13.8 12.8 12.5 15.0 15.1 18.1 12.8 10.3 55.2 18.5 33.0 46.0 27.2 29.6 29.2 12.6 13.8 146.6 14.3 22.8 18.4 64.6 24.9 18.0 34.4 29.4 14.4 4.2 12.5 12.5 17.7 18.0 30.7 43.2 11.7 9.9 23.9 44.4 14.2 5.1 19.2 12.8 85.7 13.4 25.2 71.9 22.5 30.5 14.4 15.8 4.7 23.0 13.3 8.8 15.0 12.2 13.9 10.3 55.8 58.0 11.7 29.4 23.7 30.1 21.3 58.3 26.8 13.1 43.9 32.9 27.4 30.4 43.2 29.8 32.7 36.9 43.0 19.7 15.7 26.2 38.7 EXPH5 SLAC2-B ENSG00000110723 "Exophilin 5" Q8NEV8 11 108505435-108593768 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Epidermolysis bullosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 67.7;skin 1: 25.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 147.4;Basal keratinocytes: 107.7;Glandular and luminal cells: 89.5;Respiratory ciliated cells: 98.5" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 15 "cerebellum: 67.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 7.9;hTERT-HME1: 11.2;RT4: 20.5;SK-BR-3: 9.7" "Group enriched" "Detected in many" 4 "cerebellum: 20.9;cerebral cortex: 6.7" "Region enriched" "Detected in many" 8 "cerebellum: 30.9" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "unprognostic (1.34e-3)" "unprognostic (8.36e-2)" "unprognostic (1.18e-1)" "prognostic favorable (3.42e-6)" "unprognostic (2.91e-1)" "prognostic favorable (1.46e-4)" "unprognostic (4.57e-3)" "prognostic favorable (5.12e-4)" "unprognostic (1.26e-1)" "unprognostic (3.03e-1)" "unprognostic (5.56e-3)" "unprognostic (1.33e-1)" "prognostic favorable (2.43e-4)" "unprognostic (1.18e-2)" "unprognostic (2.57e-1)" "unprognostic (3.36e-1)" "unprognostic (4.51e-1)" 0.4 0.1 1.3 0.5 2.5 0.2 2.9 67.7 2.3 2.2 12.8 3.9 0.7 0.7 2.7 7.4 1.7 0.3 0.2 2.1 1.9 2.4 7.7 3.9 0.1 1.5 3.6 0.3 1.0 4.7 0.5 2.8 4.6 1.5 4.4 0.3 4.4 0.3 0.1 25.8 0.8 0.4 1.1 0.2 3.2 0.7 1.7 0.8 1.0 0.2 1.4 0.7 3.8 3.4 3.9 0.4 0.2 0.1 0.0 0.1 3.2 0.2 0.1 0.0 0.6 1.0 5.9 0.0 0.2 0.2 0.9 7.9 5.7 2.1 0.2 0.1 1.7 1.6 0.8 0.0 0.5 0.8 0.1 0.1 3.3 0.0 11.2 0.5 0.0 1.3 3.0 0.0 3.1 0.6 1.0 0.0 0.2 6.4 2.4 0.0 0.1 0.0 0.6 20.5 1.4 0.8 1.0 9.7 0.2 1.1 6.4 0.1 0.1 0.0 2.3 0.0 1.1 0.1 0.0 0.0 0.1 0.4 0.0 0.8 0.1 0.1 0.1 0.0 0.0 0.2 0.2 0.1 0.1 0.1 0.5 0.5 0.8 0.9 0.1 0.2 0.0 0.1 1.3 2.5 67.7 2.3 2.1 1.9 1.5 3.6 4.6 1.1 1.7 3.4 0.6 147.4 60.0 18.6 0.9 107.7 12.9 16.6 58.6 0.6 14.1 8.6 5.7 4.3 65.3 20.2 14.6 44.5 2.4 47.9 3.9 5.4 10.3 74.8 7.8 2.5 4.9 3.2 9.0 4.9 4.9 5.6 20.9 89.5 1.3 0.9 0.7 24.2 3.8 0.0 4.9 38.6 14.2 0.6 15.2 2.3 0.6 1.8 5.4 16.9 1.3 0.5 1.0 3.0 0.6 3.6 17.5 0.0 1.5 30.4 1.9 3.7 98.5 1.4 0.0 0.3 2.1 1.1 0.5 46.9 72.2 54.6 2.8 0.4 29.1 19.3 F10 ENSG00000126218 "Coagulation factor X" P00742 13 113122799-113149529 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 160.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 113.6;Hepatocytes: 195.1;Leydig cells: 215.9;Peritubular cells: 236.2" "Cancer enriched" "Detected in many" 11 "liver cancer: 95.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 14.4;BJ hTERT+: 11.5;CACO-2: 12.7;fHDF/TERT166: 13.1;Hep G2: 59.6;HHSteC: 11.5;SH-SY5Y: 27.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted to blood" NA NA 13000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.18e-2)" "unprognostic (1.07e-1)" "unprognostic (7.62e-2)" "unprognostic (9.88e-2)" "unprognostic (9.44e-2)" "unprognostic (1.15e-2)" "unprognostic (4.90e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-1)" "unprognostic (1.24e-1)" "prognostic favorable (1.82e-5)" "unprognostic (6.39e-2)" "prognostic unfavorable (5.14e-5)" "unprognostic (6.60e-2)" "unprognostic (1.21e-1)" "unprognostic (3.87e-2)" "unprognostic (2.23e-3)" 21.3 8.5 1.1 1.5 1.2 0.0 11.7 2.5 2.0 53.8 1.4 5.6 10.9 13.2 16.4 8.9 23.9 10.9 40.7 1.1 1.8 4.1 160.0 14.4 3.2 2.6 1.5 27.9 7.1 0.2 4.5 4.4 2.5 12.8 2.0 0.9 5.1 7.1 6.8 20.7 11.9 2.7 1.3 3.2 8.6 10.1 1.4 1.4 8.3 6.6 1.3 11.9 25.8 1.1 0.1 0.0 2.5 0.4 8.0 8.1 0.1 14.4 11.5 0.8 0.3 12.7 0.1 0.1 0.5 13.1 1.4 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 59.6 11.5 0.0 0.3 8.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 1.5 0.1 0.0 0.3 0.0 1.3 0.2 0.3 0.1 0.0 0.0 0.2 1.0 27.9 0.1 0.5 0.1 0.6 0.6 0.1 0.0 0.0 0.8 0.2 0.0 0.2 0.0 0.1 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.2 2.5 2.0 1.1 1.8 2.6 1.5 2.5 1.3 1.4 1.1 7.0 0.0 0.0 1.3 0.6 15.7 0.1 0.0 0.0 1.1 0.4 0.3 9.1 4.3 0.0 1.8 0.0 0.6 0.0 0.1 0.0 0.1 2.9 1.9 45.9 3.8 17.9 2.7 1.3 0.0 0.4 113.6 6.1 1.0 1.3 2.2 7.9 195.1 1.4 6.7 1.4 5.0 0.0 4.8 25.0 9.6 215.9 1.3 19.6 5.6 0.6 4.5 0.0 0.5 0.1 0.3 6.5 236.2 0.0 0.3 28.3 6.4 0.0 1.2 52.6 14.5 40.9 2.3 1.2 0.5 15.3 1.1 1.9 2.4 2.2 0.4 F2 ENSG00000180210 "Coagulation factor II, thrombin" P00734 11 46719196-46739506 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1518 "liver: 1217.3" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 991.0" "Cancer enriched" "Detected in some" 110 "liver cancer: 508.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 22 "Hep G2: 281.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016780, HPA051476, HPA054698" Enhanced "Secreted to blood" NA NA 108000000000 41000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB016780: , HPA051476: AB_2681498, HPA054698: AB_2682578" "unprognostic (1.98e-1)" "unprognostic (2.52e-1)" "unprognostic (2.64e-2)" "unprognostic (1.85e-1)" "unprognostic (2.29e-1)" "unprognostic (2.81e-1)" "unprognostic (2.23e-2)" "unprognostic (3.94e-2)" "unprognostic (5.79e-2)" "unprognostic (8.29e-2)" "unprognostic (4.46e-2)" "prognostic unfavorable (6.75e-12)" "unprognostic (5.65e-3)" "unprognostic (5.80e-2)" "unprognostic (1.54e-3)" 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.2 1217.3 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.5 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12.9 0.0 0.2 2.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.5 0.2 281.0 0.0 1.5 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.8 0.3 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.3 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 20.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.2 0.0 37.5 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.3 21.8 991.0 0.0 0.0 0.2 0.2 0.0 26.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 2.0 0.0 0.0 0.1 FAHD2A CGI-105 ENSG00000115042 "Fumarylacetoacetate hydrolase domain containing 2A" Q96GK7 2 95402708-95416616 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 114.8" "Cell type enhanced" "Detected in all" "Early spermatids: 101.7;Hepatocytes: 99.3;Proximal enterocytes: 104.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042145, HPA044987, CAB045971, CAB045972" Enhanced NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 2: Hepatocytes - Metabolism" "CAB045971: AB_11126570, CAB045972: AB_11140511, HPA042145: AB_2677873, HPA044987: AB_2679170" "unprognostic (6.52e-2)" "unprognostic (1.25e-3)" "unprognostic (9.36e-2)" "unprognostic (1.27e-2)" "unprognostic (7.77e-3)" "unprognostic (6.82e-2)" "unprognostic (2.80e-2)" "unprognostic (1.08e-1)" "unprognostic (5.03e-2)" "unprognostic (1.61e-1)" "unprognostic (4.58e-2)" "unprognostic (7.30e-2)" "unprognostic (3.24e-2)" "unprognostic (1.17e-2)" "unprognostic (1.95e-1)" "unprognostic (1.88e-2)" "unprognostic (1.55e-2)" 21.0 22.1 22.6 8.7 24.2 14.7 21.8 25.5 29.7 18.4 18.8 18.3 32.4 19.0 5.3 13.3 17.8 10.9 39.3 23.5 22.4 28.6 114.8 13.9 10.9 22.3 22.4 22.6 30.0 18.1 12.3 10.8 22.7 15.5 13.9 5.9 86.2 12.2 37.8 18.5 25.4 15.3 21.2 14.6 26.1 29.9 23.3 18.6 37.8 57.9 12.2 14.3 15.7 27.6 30.2 27.9 31.7 20.4 34.4 31.1 22.4 28.2 47.5 32.5 51.6 17.6 12.9 18.5 12.1 29.1 41.0 16.2 22.8 25.7 32.3 16.0 27.9 14.9 13.2 29.1 44.3 22.8 8.2 29.9 28.6 30.0 37.9 51.6 43.2 35.6 21.6 41.1 41.6 36.6 40.6 31.1 10.2 17.6 27.2 29.9 20.0 52.0 36.3 12.1 18.9 9.3 16.8 27.0 33.2 39.3 16.9 9.0 20.4 41.2 28.3 17.6 19.6 44.0 20.3 18.8 28.0 20.5 20.9 3.3 15.7 8.1 18.2 17.8 20.7 15.5 16.7 17.6 23.3 10.4 16.8 14.2 1.0 12.3 9.0 27.3 19.6 14.4 22.6 24.2 25.5 29.7 23.5 22.4 22.3 22.4 22.7 21.2 23.3 27.6 14.6 9.6 12.5 10.7 13.8 9.8 13.8 14.6 21.1 17.6 26.6 26.4 36.8 28.6 16.8 29.5 10.4 30.3 16.6 14.4 70.5 29.5 101.7 11.2 10.5 13.9 4.9 14.5 15.2 23.1 14.7 21.4 21.9 7.7 4.5 32.7 16.4 99.3 26.0 16.8 13.2 17.3 10.2 12.0 8.3 87.1 37.0 11.0 17.8 2.8 19.8 22.2 13.4 3.5 10.8 18.7 17.3 52.3 23.9 15.4 104.6 52.7 15.0 18.8 13.1 15.3 21.3 49.1 19.1 19.0 7.7 17.1 12.4 36.5 23.9 12.1 FAM110D "FLJ14050, GRRP1" ENSG00000197245 "Family with sequence similarity 110 member D" Q8TAY7 1 26159079-26163962 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 12 "Adipocytes: 82.7;Endothelial cells: 63.5;Hepatic stellate cells: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "TIME: 1.2;U-2 OS: 1.4;U-937: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA013664 Approved NA NA "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA013664: AB_1234332" "unprognostic (7.53e-2)" "unprognostic (4.45e-3)" "unprognostic (4.80e-4)" "unprognostic (1.84e-2)" "unprognostic (1.07e-3)" "unprognostic (3.16e-3)" "unprognostic (7.67e-5)" "unprognostic (2.21e-1)" "unprognostic (1.66e-1)" "unprognostic (4.51e-2)" "unprognostic (7.29e-3)" "unprognostic (6.63e-2)" "unprognostic (9.87e-2)" "unprognostic (6.94e-2)" "unprognostic (2.91e-1)" "unprognostic (1.51e-1)" "unprognostic (2.96e-1)" 10.9 1.3 4.1 0.6 3.0 0.8 8.5 3.1 3.7 4.8 2.0 2.9 1.1 7.9 0.8 1.9 7.4 2.3 6.2 3.1 3.2 4.0 0.4 4.2 1.1 4.7 3.6 1.3 2.2 1.1 1.3 0.6 4.1 3.1 0.5 0.3 2.4 0.7 4.2 3.0 3.1 2.8 4.5 0.8 3.3 0.6 4.1 0.9 4.7 2.1 0.4 4.0 3.6 3.3 0.1 0.1 0.5 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.6 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.3 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.2 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.5 0.5 0.1 0.0 0.1 0.4 0.1 0.2 1.2 0.1 1.4 0.1 0.0 0.0 0.2 0.1 0.0 1.0 0.0 1.3 0.2 0.2 0.2 0.1 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.2 1.0 0.4 0.1 0.2 0.0 0.0 4.1 3.0 3.1 3.7 3.1 3.2 4.7 3.6 4.1 4.5 4.1 3.3 82.7 0.0 3.4 0.3 0.9 1.0 0.9 0.0 2.2 2.3 1.3 1.8 3.1 2.8 1.3 0.0 0.0 0.1 0.6 0.0 0.0 0.1 0.4 0.2 0.5 63.5 0.0 2.7 0.4 0.0 0.0 2.5 0.0 0.2 0.0 0.3 34.6 0.0 0.0 1.7 0.7 0.0 0.0 1.3 1.8 0.5 0.6 0.4 0.0 4.7 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 1.4 0.0 1.4 1.8 0.2 0.7 0.8 0.9 0.3 0.3 0.5 0.0 0.3 FAM13C FAM13C1 ENSG00000148541 "Family with sequence similarity 13 member C" Q8NE31 10 59246130-59363181 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 68.0" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 477.1" "Cancer enhanced" "Detected in some" "prostate cancer: 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 4.1;HSkMC: 5.1;hTERT-RPE1: 3.4;NTERA-2: 4.5;SCLC-21H: 8.6;SH-SY5Y: 5.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037888 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA037888: AB_10962981" "unprognostic (3.68e-1)" "unprognostic (6.10e-2)" "unprognostic (2.46e-1)" "unprognostic (6.69e-5)" "unprognostic (8.54e-2)" "unprognostic (4.56e-2)" "unprognostic (3.30e-2)" "unprognostic (1.06e-2)" "unprognostic (6.77e-2)" "unprognostic (1.32e-1)" "unprognostic (1.00e-3)" "unprognostic (3.27e-1)" "unprognostic (4.51e-6)" "unprognostic (1.02e-2)" "unprognostic (1.42e-1)" "unprognostic (1.94e-3)" "unprognostic (4.66e-3)" 13.5 16.2 20.8 3.9 45.8 0.0 9.3 33.2 32.4 8.7 3.7 7.7 4.2 8.7 8.0 13.8 14.5 11.5 8.1 21.3 34.3 3.4 2.1 9.9 4.7 49.3 36.3 21.2 2.2 4.7 4.7 2.6 40.9 17.2 6.2 9.9 5.6 7.9 17.1 7.2 5.9 12.2 35.5 5.1 3.8 5.2 37.6 5.2 6.3 22.9 2.3 4.4 7.9 68.0 0.0 0.1 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 1.3 0.2 0.1 0.0 1.2 0.0 4.1 1.9 0.1 0.0 0.0 5.1 0.6 0.2 0.0 3.4 0.0 0.0 0.0 0.2 2.1 0.0 0.0 0.0 4.5 0.0 0.4 0.0 0.8 0.0 0.0 1.3 8.6 5.0 0.0 0.2 0.0 0.3 0.7 0.0 0.0 2.5 2.2 0.1 2.1 0.0 0.0 0.1 3.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.8 45.8 33.2 32.4 21.3 34.3 49.3 36.3 40.9 35.5 37.6 68.0 47.8 0.0 0.0 33.6 0.1 4.8 9.3 0.3 8.0 10.5 0.7 2.7 2.5 0.0 0.7 0.0 6.2 0.0 0.4 0.1 7.9 0.0 49.0 18.6 1.5 35.2 0.0 0.0 66.8 0.0 0.0 19.8 0.5 5.3 0.0 26.9 3.9 0.5 0.0 3.3 73.2 0.2 20.3 0.0 2.5 22.1 23.0 0.7 3.6 7.5 0.0 8.8 0.0 56.8 477.1 0.0 0.0 21.1 0.1 5.4 0.0 0.6 20.7 13.6 39.5 23.4 36.2 1.4 0.7 2.4 6.3 0.0 1.2 17.4 0.2 1.1 FAM151A "C1orf179, MGC27169" ENSG00000162391 "Family with sequence similarity 151 member A" Q8WW52 1 54609181-54623556 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 66.3;kidney: 174.5" "Group enriched" "Detected in some" 15 "Proximal enterocytes: 478.5;Proximal tubular cells: 294.8" "Group enriched" "Detected in many" 5 "liver cancer: 2.3;renal cancer: 3.2;testis cancer: 5.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 44 "CACO-2: 78.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA016840 Approved NA NA 10000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA016840: AB_2669461" "unprognostic (1.89e-1)" "unprognostic (6.90e-3)" "unprognostic (3.73e-2)" "unprognostic (1.97e-6)" "unprognostic (1.71e-2)" "unprognostic (4.84e-3)" "unprognostic (1.02e-1)" "unprognostic (3.46e-2)" "unprognostic (2.87e-1)" "unprognostic (1.05e-2)" "unprognostic (4.91e-3)" "unprognostic (9.99e-2)" "prognostic favorable (4.09e-5)" "unprognostic (5.85e-2)" "unprognostic (8.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.40e-3)" 0.6 0.3 0.5 0.6 1.5 0.2 0.1 1.6 0.9 0.0 5.9 2.4 2.4 0.1 0.0 0.3 0.0 0.1 3.0 0.6 0.5 174.5 16.7 0.0 5.3 2.7 2.8 0.3 0.6 0.0 0.1 0.0 1.5 0.1 1.3 0.3 0.5 0.0 1.0 0.1 66.3 0.0 0.4 0.8 0.7 0.6 2.2 0.2 0.4 0.0 1.8 0.1 0.0 0.6 0.7 0.1 0.1 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 78.9 0.9 0.0 0.3 0.0 0.2 1.1 0.0 0.0 0.0 0.5 0.0 1.7 0.4 0.4 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 1.5 0.0 0.0 0.8 0.0 0.0 1.6 0.4 0.5 0.1 0.0 0.0 0.3 0.0 0.5 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.5 1.6 0.9 0.6 0.5 2.7 2.8 1.5 0.4 2.2 0.6 0.0 0.0 0.0 3.6 2.4 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 7.3 0.0 0.0 0.0 9.3 13.7 0.0 5.2 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.2 0.0 0.0 0.4 16.8 0.0 0.3 0.0 14.3 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 25.0 0.0 0.0 0.0 478.5 294.8 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.0 0.1 18.1 0.0 FAM162B "bA86F4.2, C6orf189" ENSG00000183807 "Family with sequence similarity 162 member B" Q5T6X4 6 116752197-116765719 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 65.2" "Group enriched" "Detected in some" 4 "Adipocytes: 34.6;Sertoli cells: 65.7;Smooth muscle cells: 105.1" "Cancer enriched" "Detected in many" 18 "testis cancer: 32.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 8.7;BJ hTERT+: 23.5;BJ hTERT+ SV40 Large T+ RasG12V: 22.1;HHSteC: 6.3;HSkMC: 7.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036112, HPA060342" Enhanced NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA036112: AB_10696649, HPA060342: AB_2684258" "unprognostic (1.81e-1)" "unprognostic (5.65e-3)" "unprognostic (1.54e-1)" "unprognostic (3.38e-1)" "unprognostic (5.45e-2)" "unprognostic (1.86e-5)" "unprognostic (8.29e-2)" "unprognostic (1.24e-1)" "unprognostic (4.19e-2)" "unprognostic (2.44e-2)" "unprognostic (7.32e-2)" "unprognostic (6.27e-3)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.22e-2)" "unprognostic (1.72e-1)" "unprognostic (2.73e-3)" "unprognostic (4.34e-2)" 14.7 14.9 3.3 0.8 4.4 0.0 10.9 1.9 7.0 13.2 2.5 3.3 0.9 5.8 7.5 4.4 10.1 5.2 9.1 4.6 2.7 4.5 0.9 17.9 1.5 3.0 2.5 5.7 1.7 3.7 6.6 65.2 2.7 6.2 2.1 0.2 8.2 13.4 5.4 3.0 2.3 3.7 2.7 0.1 3.5 2.5 2.8 1.8 9.7 10.6 1.2 7.9 9.9 4.7 0.0 0.0 0.0 0.0 2.3 0.1 0.0 8.7 23.5 3.7 22.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.3 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 4.4 1.9 7.0 4.6 2.7 3.0 2.5 2.7 2.7 2.8 4.7 34.6 0.0 0.0 1.3 0.0 1.3 0.1 0.0 1.2 0.0 0.9 0.8 0.9 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 16.9 0.7 15.7 13.7 0.0 0.0 14.8 0.0 0.2 14.1 0.0 0.4 0.0 0.1 3.6 0.0 0.5 0.0 6.9 0.0 0.0 0.0 2.1 2.2 2.1 0.7 1.8 3.7 0.0 0.0 0.0 6.6 0.5 0.2 0.0 5.3 0.0 0.2 0.0 0.1 0.0 0.1 65.7 2.2 105.1 10.3 5.9 0.6 0.9 0.5 2.3 0.1 0.0 0.0 FAM180A "HWKM1940, UNQ1940" ENSG00000189320 "Family with sequence similarity 180 member A" Q6UWF9 7 135728348-135748813 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 16.1;heart muscle: 15.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.5;Cardiomyocytes: 6.6;Fibroblasts: 19.7;Hepatic stellate cells: 4.6;Langerhans cells: 9.5;Melanocytes: 7.2;Suprabasal keratinocytes: 4.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "U-2197: 259.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA021224 Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA021224: AB_1851352" "unprognostic (3.85e-2)" "unprognostic (9.13e-2)" "unprognostic (1.42e-1)" "unprognostic (2.57e-1)" "unprognostic (2.54e-1)" "unprognostic (2.33e-2)" "unprognostic (6.85e-2)" "unprognostic (1.27e-1)" "unprognostic (5.05e-2)" "unprognostic (1.97e-3)" "unprognostic (5.62e-2)" "unprognostic (7.55e-2)" "unprognostic (8.88e-4)" "unprognostic (3.14e-3)" "unprognostic (1.82e-1)" "unprognostic (4.35e-4)" "unprognostic (6.62e-4)" 3.1 2.7 0.0 0.5 0.1 0.1 3.4 0.1 0.3 2.6 4.2 1.8 0.8 4.7 0.4 4.0 2.0 16.1 15.9 0.3 0.0 4.1 10.2 2.5 0.1 0.0 0.0 7.9 1.3 0.2 0.1 0.2 0.0 0.6 2.0 0.0 1.2 0.2 0.3 3.4 1.3 4.7 0.0 0.6 1.0 0.4 0.0 0.2 2.7 1.3 0.5 4.4 1.3 0.1 0.0 0.1 0.0 0.0 27.8 28.4 0.0 14.9 56.2 0.3 0.2 0.0 0.0 0.0 0.0 57.8 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 2.6 0.0 35.6 4.6 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.6 57.1 0.0 259.7 0.0 0.0 0.1 0.0 1.9 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.1 0.8 6.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.8 0.0 0.0 0.3 0.0 0.0 19.7 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 9.5 0.0 2.8 0.1 7.2 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.5 1.8 0.0 0.0 0.1 4.8 0.7 0.2 0.0 0.0 0.0 FAM184A "C6orf60, FLJ13942" ENSG00000111879 "Family with sequence similarity 184 member A" Q8NB25 6 118959763-119149387 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.3;choroid plexus: 30.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 103.0;Astrocytes: 261.2;Oligodendrocyte precursor cells: 88.4;Syncytiotrophoblasts: 266.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 11.8;HEK 293: 11.1;Hep G2: 7.9;JURKAT: 11.6;K-562: 10.4;SCLC-21H: 8.5;SH-SY5Y: 8.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034571, HPA034572, HPA041955" Uncertain Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA034571: AB_10602498, HPA034572: AB_2674228, HPA041955: AB_2677768" "unprognostic (1.21e-1)" "unprognostic (4.11e-3)" "unprognostic (6.95e-2)" "unprognostic (3.40e-3)" "unprognostic (6.80e-2)" "unprognostic (1.64e-2)" "unprognostic (1.03e-1)" "unprognostic (1.18e-4)" "unprognostic (2.59e-1)" "unprognostic (3.19e-1)" "unprognostic (5.16e-4)" "unprognostic (8.38e-3)" "unprognostic (4.02e-2)" "unprognostic (9.11e-3)" "unprognostic (8.16e-3)" "unprognostic (5.70e-2)" "unprognostic (2.32e-1)" 3.1 1.6 33.3 1.3 36.3 0.2 4.7 37.3 43.3 3.6 30.5 3.5 3.0 2.5 3.0 1.4 3.2 1.8 2.5 34.3 33.0 6.7 6.3 9.9 3.5 31.9 32.4 4.5 3.2 4.8 11.0 23.0 32.4 3.9 0.9 16.3 3.3 2.8 0.9 1.7 1.6 1.6 29.1 0.6 1.7 16.9 32.6 0.6 7.0 2.2 3.5 2.4 2.1 34.5 0.1 0.3 11.8 0.9 0.3 0.3 0.0 0.6 0.4 0.5 0.9 2.0 1.1 0.9 0.0 0.2 5.3 0.0 3.4 0.0 0.2 1.3 11.1 0.1 0.9 7.9 0.2 0.0 0.6 0.4 0.1 0.1 0.0 0.3 0.0 11.6 10.4 0.7 0.3 0.3 0.4 0.1 6.0 0.6 1.3 0.0 0.1 0.0 0.1 0.1 8.5 8.0 0.7 0.6 1.8 2.2 2.1 1.4 0.3 0.8 0.5 0.2 2.9 4.9 3.3 0.3 1.5 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.3 0.0 33.3 36.3 37.3 43.3 34.3 33.0 31.9 32.4 32.4 29.1 32.6 34.5 21.0 48.1 103.0 261.2 0.7 2.4 5.9 0.4 11.4 35.2 3.8 8.8 6.4 2.8 17.7 3.7 29.2 61.4 0.6 0.4 17.6 1.0 22.9 2.0 2.0 5.3 6.0 0.4 66.9 1.1 18.9 11.8 1.5 0.8 6.3 8.9 1.8 4.0 5.6 13.5 55.5 0.6 0.0 0.3 1.8 9.2 3.7 1.0 0.0 34.7 0.0 11.1 0.0 88.4 20.6 0.3 1.2 7.2 2.7 1.6 0.4 3.1 37.3 28.4 6.6 45.2 4.1 61.8 16.0 4.2 3.4 266.4 5.8 1.4 0.7 2.0 FAM186B "C12orf25, DKFZP434J0113" ENSG00000135436 "Family with sequence similarity 186 member B" Q8IYM0 12 49582885-49605639 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "testis: 46.0" "Group enriched" "Detected in some" 17 "Early spermatids: 85.1;Late spermatids: 101.5;Spermatocytes: 38.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039736, HPA040028" Uncertain NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 83: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA039736: AB_10795295, HPA040028: AB_10795684" "unprognostic (2.96e-1)" "unprognostic (1.25e-1)" "unprognostic (2.86e-1)" "unprognostic (1.94e-1)" "unprognostic (3.00e-1)" "unprognostic (5.55e-2)" "unprognostic (1.53e-1)" "unprognostic (3.37e-3)" "unprognostic (1.44e-1)" "unprognostic (4.11e-2)" "unprognostic (4.47e-2)" "unprognostic (2.80e-1)" "unprognostic (4.42e-5)" "unprognostic (1.56e-1)" "unprognostic (6.18e-2)" "unprognostic (2.10e-5)" "unprognostic (7.23e-2)" 0.2 0.5 0.3 0.4 0.4 0.5 0.3 0.9 0.5 0.3 0.0 0.3 0.3 0.3 0.3 0.2 0.4 0.2 0.3 0.3 0.4 0.5 0.8 0.2 0.6 0.2 0.0 0.8 1.6 0.9 0.3 0.1 0.0 0.3 0.1 0.6 0.4 0.2 0.6 1.2 0.3 0.1 0.1 0.3 0.4 46.0 0.4 0.1 1.0 0.3 0.2 0.3 0.3 0.6 0.3 1.4 0.1 0.4 0.1 0.0 0.7 0.0 0.1 0.0 0.1 1.8 0.5 1.0 0.3 0.1 0.3 0.5 0.2 0.2 0.1 0.3 0.4 0.6 0.9 0.2 0.1 1.1 0.3 0.0 0.3 0.2 0.7 0.1 0.1 0.4 1.0 0.8 0.2 1.0 0.1 0.1 0.2 0.4 0.5 0.4 0.1 0.4 0.5 0.4 1.1 0.3 0.5 0.2 0.8 0.3 0.6 0.5 0.5 0.1 0.5 0.4 0.3 0.5 0.4 1.8 0.2 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.4 0.9 0.5 0.3 0.4 0.2 0.0 0.0 0.1 0.4 0.6 0.1 0.0 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.4 0.2 0.0 0.4 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 85.1 0.2 0.1 0.2 0.0 0.0 0.7 0.2 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.9 0.1 0.0 0.7 0.0 0.0 0.0 0.0 101.5 1.2 0.2 0.0 1.0 0.0 0.1 0.0 0.0 1.0 0.1 0.1 0.7 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.5 0.2 38.2 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 FAT3 "CDHF15, CDHR10, KIAA1989" ENSG00000165323 "FAT atypical cadherin 3" Q8TDW7 11 92224818-92896473 "Predicted membrane proteins" "Cell adhesion" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 19.3" "Cell type enhanced" "Detected in some" "Astrocytes: 265.8;Excitatory neurons: 512.9;Inhibitory neurons: 149.2;Oligodendrocyte precursor cells: 88.4" "Cancer enriched" "Detected in single" 6 "glioma: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.3;fHDF/TERT166: 2.2;NTERA-2: 2.5;SuSa: 2.2;U-2 OS: 2.1;U-251 MG: 4.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026878, HPA074824" Uncertain Approved "Cell Junctions" NA NA 4700 "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions" "HPA026878: AB_1848430, HPA074824: " "unprognostic (5.00e-2)" "unprognostic (1.37e-1)" "unprognostic (8.61e-2)" "unprognostic (4.76e-6)" "unprognostic (1.27e-1)" "unprognostic (1.79e-1)" "unprognostic (1.56e-1)" "unprognostic (9.32e-2)" "unprognostic (1.08e-1)" "unprognostic (3.04e-2)" "unprognostic (1.46e-1)" "unprognostic (1.09e-1)" "unprognostic (5.79e-2)" "unprognostic (3.66e-4)" "unprognostic (8.83e-2)" "unprognostic (7.72e-2)" "unprognostic (2.25e-1)" 0.5 0.0 5.5 0.0 19.3 0.0 0.1 1.3 9.0 0.6 0.0 0.2 0.0 0.6 0.6 0.1 0.6 0.0 0.2 4.0 15.5 0.2 0.0 1.2 0.0 0.5 4.7 0.5 0.0 0.0 2.9 0.1 1.9 2.0 0.1 1.3 0.0 3.8 0.1 0.2 0.0 0.1 0.8 0.1 2.2 0.7 7.5 0.1 0.0 0.2 0.2 2.3 1.0 1.0 0.0 0.3 7.3 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.4 0.0 0.0 0.0 1.4 2.2 0.0 1.2 0.0 0.0 0.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.6 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.2 2.1 0.0 4.3 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 19.3 1.3 9.0 4.0 15.5 0.5 4.7 1.9 0.8 7.5 1.0 0.0 0.0 0.0 265.8 0.0 0.1 0.3 0.9 0.0 20.8 0.1 0.5 1.8 0.0 0.1 14.7 0.0 0.1 0.0 0.1 0.0 0.7 4.8 0.1 0.2 0.2 0.0 0.0 512.9 0.0 0.1 1.9 0.0 0.0 0.0 3.7 1.4 0.0 0.1 0.0 149.2 0.0 24.4 0.0 0.0 3.8 1.2 0.3 0.0 13.1 0.0 0.8 0.0 88.4 7.0 0.2 0.0 7.5 0.0 0.6 0.0 0.0 0.0 1.7 0.0 2.5 4.4 1.0 6.5 0.1 0.0 0.0 0.0 44.8 0.0 0.1 FBLN2 ENSG00000163520 "Fibulin 2" P98095 3 13549125-13638422 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 292.8" "Cell type enhanced" "Detected in many" "Adipocytes: 92.7;Endometrial stromal cells: 84.4;Fibroblasts: 458.4;Leydig cells: 170.9;Peritubular cells: 227.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 6.7;naive CD8 T-cell: 3.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 384.0;fHDF/TERT166: 264.3;HMC-1: 311.6;HSkMC: 221.9;U-2197: 139.2" "Group enriched" "Detected in many" 4 "olfactory bulb: 12.4;white matter: 3.1" "Low region specificity" "Detected in all" "HPA001934, CAB018622" Enhanced Supported "Plasma membrane" "Secreted to extracellular matrix" NA NA 35000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB018622: AB_2294196, HPA001934: AB_1078827" "unprognostic (1.19e-1)" "unprognostic (7.76e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (2.82e-2)" "unprognostic (1.05e-1)" "prognostic favorable (3.17e-4)" "unprognostic (8.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.70e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-2)" "unprognostic (2.13e-2)" "unprognostic (1.89e-2)" "unprognostic (2.82e-2)" "unprognostic (2.61e-2)" "unprognostic (1.41e-1)" 157.3 7.6 5.9 12.7 7.7 1.0 97.3 5.2 9.0 63.4 6.4 32.7 6.2 31.1 3.2 42.4 26.8 46.2 292.8 7.0 4.9 8.7 3.7 29.2 8.4 5.3 5.3 5.8 8.6 3.0 2.3 80.3 4.8 29.1 11.8 0.6 39.4 8.8 47.7 72.5 19.8 14.7 4.1 6.0 22.3 46.7 6.9 14.2 63.7 48.9 5.6 79.6 56.7 4.4 0.0 1.4 50.9 0.0 384.0 51.7 23.8 124.9 98.2 122.4 80.4 8.1 0.3 0.0 5.9 264.3 0.2 0.2 0.0 0.5 22.9 0.1 0.1 100.7 1.9 0.0 26.0 0.2 311.6 221.9 2.0 19.3 0.0 0.2 0.0 8.6 0.8 0.9 0.6 0.3 5.2 0.6 12.2 0.0 0.7 0.2 0.0 0.5 0.9 0.1 3.0 2.4 0.5 90.3 0.1 13.6 0.2 0.3 0.1 0.1 0.1 139.2 0.1 0.2 0.0 0.0 1.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.2 6.7 1.3 0.0 3.7 0.0 0.2 0.0 0.5 0.0 0.9 5.9 7.7 5.2 9.0 7.0 4.9 5.3 5.3 4.8 4.1 6.9 4.4 92.7 0.0 1.5 1.6 3.6 30.8 0.8 10.5 2.2 0.0 1.7 1.9 8.8 0.0 12.3 7.3 2.1 7.8 1.9 0.1 0.0 0.0 3.8 2.9 84.4 43.8 0.0 1.7 0.6 0.2 4.8 458.4 6.1 2.7 23.6 0.6 47.8 0.4 3.6 0.0 0.6 0.0 0.0 1.9 49.8 12.1 170.9 4.5 39.2 26.2 0.3 1.2 0.0 30.7 0.3 0.3 0.0 227.2 1.6 1.2 2.7 0.1 1.4 0.4 13.1 29.7 26.4 3.4 13.5 2.0 28.8 6.2 5.3 0.2 0.0 1.1 FBLN5 "ARMD3, DANCE, EVEC, UP50" ENSG00000140092 "Fibulin 5" Q9UBX5 14 91869411-91947987 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Age-related macular degeneration, Charcot-Marie-Tooth disease, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Fibroblasts: 209.4;Leydig cells: 626.6;Peritubular cells: 794.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.6" "Group enriched" "Detected in many" 19 "granulocytes: 6.6;T-cells: 1.8" "Cell line enhanced" "Detected in many" "ASC diff: 457.1;ASC TERT1: 234.6;BJ: 202.0;BJ hTERT+: 202.5;fHDF/TERT166: 394.6;HSkMC: 216.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000848, HPA000868, CAB025843" Supported Uncertain "Plasma membrane" "Secreted to extracellular matrix" NA NA 12000000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB025843: , HPA000848: AB_1078620, HPA000868: AB_1078619" "unprognostic (5.53e-3)" "unprognostic (1.14e-1)" "unprognostic (7.78e-2)" "unprognostic (9.29e-2)" "unprognostic (5.55e-3)" "unprognostic (4.73e-2)" "prognostic favorable (6.75e-4)" "unprognostic (5.21e-3)" "unprognostic (4.76e-2)" "unprognostic (1.25e-2)" "unprognostic (3.74e-2)" "unprognostic (1.90e-1)" "unprognostic (7.26e-2)" "unprognostic (1.56e-3)" "unprognostic (1.73e-1)" "unprognostic (5.18e-2)" "unprognostic (3.17e-3)" 182.2 73.4 10.7 17.7 12.8 7.5 110.4 7.4 12.5 124.9 15.7 80.3 19.1 178.4 40.0 26.8 143.0 130.2 211.1 9.4 8.6 108.4 29.3 164.8 25.5 15.5 10.9 107.3 46.4 16.8 14.5 67.0 14.2 49.0 20.6 0.6 55.8 70.9 30.4 66.9 52.7 88.7 13.1 130.9 68.9 35.6 12.7 21.8 79.5 36.0 15.7 117.5 93.3 7.5 0.0 1.6 0.2 0.0 457.1 234.6 22.5 202.0 202.5 5.8 4.5 4.7 0.0 0.0 4.2 394.6 0.6 0.1 9.8 1.0 1.0 0.0 2.3 0.4 4.7 0.0 74.2 0.0 0.1 216.6 0.4 3.9 14.1 2.8 10.4 0.1 0.0 0.1 25.3 0.4 0.5 0.5 0.5 0.0 0.5 0.4 30.2 0.2 1.2 0.1 0.2 0.1 12.3 0.7 2.6 7.0 2.9 0.3 1.9 3.2 6.6 3.8 0.1 0.1 0.0 0.2 0.4 0.0 0.0 6.6 0.1 2.2 0.8 0.2 0.5 0.0 0.3 0.1 0.0 0.1 1.1 1.8 2.5 0.0 0.2 0.0 0.1 0.4 10.7 12.8 7.4 12.5 9.4 8.6 15.5 10.9 14.2 13.1 12.7 7.5 31.4 83.3 13.1 0.0 2.1 9.2 2.4 7.1 1.8 0.0 11.2 9.3 5.2 0.0 11.5 5.5 0.0 2.5 2.5 0.1 5.9 4.7 5.9 13.3 67.4 15.2 0.0 0.4 2.6 4.7 2.5 209.4 2.0 12.0 2.5 1.8 34.2 0.4 7.8 0.0 3.6 0.1 18.3 2.5 18.4 27.5 626.6 5.8 21.4 15.9 1.6 0.0 8.2 5.0 2.3 2.2 0.0 794.8 0.7 1.3 0.0 32.5 21.4 0.0 6.6 28.0 14.5 3.0 2.8 1.3 8.7 3.7 15.5 3.5 0.4 1.2 FBLN7 "FLJ37440, TM14" ENSG00000144152 "Fibulin 7" Q53RD9 2 112138385-112188218 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 14.4;Fibroblasts: 16.6;Inhibitory neurons: 30.7;Melanocytes: 17.8;Skeletal myocytes: 19.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 26 "memory CD4 T-cell: 34.4;naive CD4 T-cell: 29.5;T-reg: 36.5" "Lineage enriched" "Detected in many" 35 "T-cells: 36.5" "Cell line enhanced" "Detected in many" "AF22: 24.5;BJ hTERT+: 17.7;hTERT-RPE1: 12.8;SCLC-21H: 15.8;SH-SY5Y: 12.6;U-2197: 25.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034992 Approved "Plasma membrane,Cell Junctions" "Secreted to extracellular matrix" NA NA 310000 "Cluster 20: T-cells - T-cell receptor" "Cluster 34: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Cell Junctions" "HPA034992: AB_10601469" "unprognostic (1.72e-1)" "unprognostic (1.47e-1)" "unprognostic (5.88e-2)" "unprognostic (4.88e-3)" "unprognostic (1.24e-1)" "unprognostic (1.70e-3)" "unprognostic (4.34e-2)" "unprognostic (4.80e-2)" "unprognostic (5.77e-2)" "unprognostic (2.01e-1)" "unprognostic (7.91e-2)" "unprognostic (2.02e-2)" "unprognostic (2.35e-2)" "unprognostic (3.11e-2)" "unprognostic (8.10e-2)" "unprognostic (1.21e-2)" "unprognostic (9.33e-2)" 6.5 4.0 0.8 4.3 0.6 0.7 7.8 4.0 6.4 10.3 0.4 1.8 1.1 4.8 2.8 1.9 7.1 3.4 2.5 2.1 3.8 1.5 5.2 2.7 9.8 9.2 4.4 1.4 2.4 6.9 12.2 3.2 9.7 3.3 1.3 2.5 2.5 3.1 1.4 5.5 2.9 2.2 2.2 5.6 3.0 0.5 4.1 8.6 10.7 2.5 6.0 2.5 7.5 1.1 0.0 0.1 24.5 0.0 2.6 1.9 0.1 5.5 17.7 5.9 9.2 0.0 0.2 0.0 0.1 8.3 1.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.9 1.1 1.2 0.0 0.0 1.9 0.1 9.9 0.0 12.8 1.4 0.3 0.0 0.0 2.1 0.0 0.7 0.1 0.6 0.0 0.5 0.0 0.0 6.6 0.3 0.0 15.8 12.6 0.1 0.1 0.7 0.1 0.7 0.2 5.2 0.8 0.7 25.4 0.8 0.0 0.0 0.0 0.8 0.0 2.1 0.0 0.0 0.0 0.4 0.0 1.3 0.0 34.4 0.4 0.0 0.0 29.5 1.0 0.0 0.0 0.0 1.0 36.5 6.2 0.8 0.6 4.0 6.4 2.1 3.8 9.2 4.4 9.7 2.2 4.1 1.1 1.4 3.2 0.5 0.3 0.7 4.5 1.0 0.3 0.0 3.8 1.0 2.4 1.1 0.0 0.0 0.0 0.0 4.0 0.2 0.0 0.0 0.3 1.7 1.2 5.9 2.6 0.0 0.0 14.4 0.2 10.1 16.6 0.0 1.2 1.3 0.7 0.4 2.2 0.5 3.3 30.7 0.0 0.0 0.0 4.0 3.6 0.3 0.4 17.8 1.9 0.0 2.3 0.0 6.6 0.9 0.6 0.0 5.3 0.1 0.4 0.1 0.5 0.3 7.6 6.6 19.3 7.8 0.1 0.4 0.1 3.8 1.5 7.7 0.2 0.0 0.3 FBXO7 "Fbx, FBX7, PARK15" ENSG00000100225 "F-box protein 7" Q9Y3I1 22 32474676-32498829 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 279.9" "Cell type enhanced" "Detected in all" "Erythroid cells: 680.9;Late spermatids: 620.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032113, HPA032114, CAB034296" Uncertain Supported Nucleoplasm,Cytosol NA NA 550000 "Cluster 2: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Cytosol" "CAB034296: AB_2102563, HPA032113: AB_2674156, HPA032114: AB_10696202" "unprognostic (3.99e-2)" "unprognostic (1.53e-1)" "prognostic favorable (1.08e-5)" "unprognostic (1.36e-1)" "unprognostic (2.82e-1)" "unprognostic (2.11e-2)" "unprognostic (1.79e-1)" "unprognostic (1.29e-1)" "unprognostic (1.03e-1)" "unprognostic (2.45e-2)" "unprognostic (2.28e-1)" "unprognostic (2.53e-1)" "prognostic favorable (2.66e-10)" "unprognostic (3.33e-2)" "unprognostic (1.65e-1)" "unprognostic (7.02e-2)" "unprognostic (1.79e-3)" 51.6 61.7 70.3 35.9 86.8 279.9 52.9 79.9 86.5 53.5 72.3 53.5 47.7 49.2 68.7 40.1 66.6 43.9 38.5 68.3 76.2 106.5 128.4 59.6 54.6 85.0 83.8 62.7 41.0 75.9 50.6 71.5 84.1 42.6 53.8 40.1 43.1 53.5 31.0 50.6 48.4 57.1 79.0 65.6 48.4 99.5 79.8 77.9 134.2 48.3 61.8 54.8 44.0 97.8 72.1 52.1 69.3 77.1 105.8 99.5 45.9 64.3 119.6 102.7 121.9 54.4 51.1 71.2 49.6 114.6 87.8 47.6 103.3 84.7 105.1 111.8 80.9 99.1 54.4 83.7 126.8 126.2 82.8 83.8 134.1 90.6 69.2 93.4 112.2 53.1 77.5 88.0 112.7 57.7 65.3 81.2 26.7 102.3 36.1 64.1 72.2 84.0 118.2 81.0 96.6 63.1 81.3 62.4 235.2 98.3 34.0 67.2 76.0 50.6 69.4 48.4 49.5 62.1 69.3 67.6 97.4 65.6 212.3 251.5 59.9 132.1 83.3 70.6 101.5 70.2 75.9 84.9 82.2 63.6 65.6 72.6 22.4 98.3 74.9 55.8 101.3 90.4 70.3 86.8 79.9 86.5 68.3 76.2 85.0 83.8 84.1 79.0 79.8 97.8 48.8 41.7 25.3 37.9 60.4 46.3 69.4 72.7 48.9 26.0 46.5 32.3 16.1 65.8 48.1 49.7 18.8 90.2 73.6 43.4 97.8 75.3 303.3 41.3 37.8 53.1 67.6 680.9 27.6 77.4 108.9 47.9 40.2 47.2 55.8 63.6 53.9 88.6 71.9 33.7 26.7 42.7 65.1 64.8 53.2 620.8 45.1 55.0 119.2 28.1 125.2 54.1 72.1 101.0 170.6 77.2 58.0 48.9 62.7 68.3 72.2 152.9 34.2 38.1 46.0 35.3 46.2 149.4 136.9 42.3 43.3 71.6 62.3 41.8 47.2 83.7 FCGR3A "CD16, CD16a, FCG3, FCGR3" ENSG00000203747 "Fc fragment of IgG receptor IIIa" P08637 1 161541759-161550737 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 206.3;lymphoid tissue: 306.8" "Cell type enhanced" "Detected in many" "dendritic cells: 333.4;Hofbauer cells: 193.1;Kupffer cells: 807.9;Macrophages: 300.0;NK-cells: 579.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "intermediate monocyte: 1763.5;neutrophil: 1169.8;non-classical monocyte: 3948.7" "Group enriched" "Detected in all" 5 "granulocytes: 1169.8;monocytes: 3948.7" "Not detected" "Not detected" "CAB032435, HPA055431" Supported "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB032435: AB_626925, HPA055431: AB_2682815" "unprognostic (5.27e-2)" "unprognostic (9.95e-2)" "unprognostic (2.37e-2)" "unprognostic (1.66e-1)" "unprognostic (1.39e-1)" "unprognostic (1.82e-1)" "unprognostic (2.24e-2)" "unprognostic (6.06e-2)" "unprognostic (2.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.98e-2)" "unprognostic (7.52e-2)" "prognostic unfavorable (3.22e-6)" "unprognostic (1.14e-1)" "unprognostic (4.66e-2)" "unprognostic (1.03e-2)" "unprognostic (7.51e-2)" 52.9 41.9 18.4 99.8 20.4 27.3 14.7 19.3 27.2 8.2 26.5 12.5 5.8 5.9 5.9 4.9 9.1 24.5 22.3 16.9 22.0 7.9 111.5 206.3 37.1 37.7 27.9 6.6 7.8 13.6 11.3 71.0 30.6 6.9 12.6 6.9 14.7 7.6 3.3 2.2 5.7 68.4 31.7 306.8 6.8 7.7 28.8 9.3 7.0 4.3 3.9 32.5 3.5 39.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.5 26.2 9.6 513.6 1763.5 4.9 3.7 4.7 205.9 175.8 1.4 3.0 184.0 1169.8 136.2 3948.7 4.6 2.6 734.1 18.4 20.4 19.3 27.2 16.9 22.0 37.7 27.9 30.6 31.7 28.8 39.8 2.7 22.4 24.6 0.7 6.5 0.5 0.1 0.0 0.0 0.2 1.4 3.4 0.7 8.6 10.5 3.7 2.1 1.2 333.4 0.0 0.0 0.2 1.4 0.1 0.0 18.9 0.0 16.4 0.0 0.0 1.4 3.9 0.0 0.1 18.9 0.1 8.6 5.3 193.1 0.0 0.1 0.1 0.0 807.9 7.4 3.7 0.3 300.0 0.0 20.6 77.2 0.1 579.9 0.0 0.1 0.0 0.0 0.0 22.1 0.0 0.0 0.8 5.8 1.5 19.7 1.1 0.4 0.0 0.5 0.2 0.0 2.1 88.0 0.0 0.0 0.3 FCGRT "alpha-chain, FCRN" ENSG00000104870 "Fc fragment of IgG receptor and transporter" P55899 19 49506816-49526428 "Predicted intracellular proteins, Predicted membrane proteins" "IgG-binding protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1362.6;Kupffer cells: 877.7;Paneth cells: 883.9;Proximal enterocytes: 1787.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 2346.7" "Group enriched" "Detected in all" 17 "dendritic cells: 922.9;granulocytes: 2346.7;monocytes: 1364.4" "Cell line enhanced" "Detected in many" "ASC diff: 153.7;Hep G2: 144.0;OE19: 165.4;THP-1: 196.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012122, HPA015130" Enhanced NA NA 24000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 4: Macrophages - Innate immune response" "HPA012122: AB_1848474, HPA015130: AB_1848475" "unprognostic (2.19e-3)" "unprognostic (2.05e-2)" "unprognostic (1.89e-1)" "unprognostic (1.69e-2)" "unprognostic (2.39e-1)" "unprognostic (1.26e-1)" "unprognostic (8.58e-2)" "unprognostic (3.87e-3)" "unprognostic (2.81e-1)" "unprognostic (3.49e-2)" "unprognostic (2.00e-3)" "unprognostic (3.64e-1)" "unprognostic (3.67e-3)" "unprognostic (3.40e-1)" "unprognostic (1.40e-1)" "unprognostic (1.29e-2)" "unprognostic (2.18e-3)" 263.1 127.7 67.7 99.6 73.3 147.3 198.8 68.0 102.5 217.2 111.1 209.6 304.4 143.1 48.8 60.2 155.5 144.6 123.0 66.3 75.1 177.6 401.6 177.5 143.3 74.0 69.5 193.2 129.4 114.5 79.8 137.5 74.3 104.6 149.3 4.8 106.2 94.7 64.4 112.3 299.3 91.6 73.6 318.9 126.6 28.3 78.8 62.9 111.9 77.8 39.1 136.7 132.0 78.2 0.4 37.1 4.3 123.7 153.7 78.2 6.0 32.1 73.4 20.9 22.9 50.5 22.5 0.2 59.4 45.9 10.8 8.5 1.2 1.1 11.7 0.3 45.5 74.2 0.6 144.0 95.8 1.1 14.2 95.1 1.9 17.5 0.2 86.5 81.3 48.0 12.2 10.9 53.7 0.8 0.6 14.3 2.1 165.4 22.0 2.6 35.3 3.7 96.0 9.3 2.6 23.1 5.6 0.2 4.5 18.3 26.5 196.1 28.1 52.8 11.8 0.9 1.3 2.4 13.5 9.8 10.8 70.2 7.9 566.8 1364.4 1011.5 24.7 904.8 29.8 58.0 39.8 39.7 922.9 62.5 89.4 51.0 2346.7 28.6 630.2 536.4 28.2 1276.9 67.7 73.3 68.0 102.5 66.3 75.1 74.0 69.5 74.3 73.6 78.8 78.2 479.6 67.3 89.3 21.2 44.2 126.1 130.4 130.7 52.9 0.7 125.5 151.3 30.7 158.7 79.9 73.5 4.2 12.7 83.8 652.3 60.7 86.3 6.5 29.1 89.6 259.2 158.1 55.8 0.2 61.6 24.9 269.9 108.6 24.8 70.5 181.2 587.6 343.9 1362.6 0.0 0.2 349.0 57.0 877.7 438.1 21.8 362.2 608.6 186.7 24.4 190.6 13.4 11.3 10.1 0.2 90.6 883.9 183.6 63.2 87.9 1787.7 329.5 53.4 5.2 216.9 149.2 105.6 21.1 17.6 27.7 107.1 20.7 32.4 129.9 565.1 115.4 FECH ENSG00000066926 Ferrochelatase P22830 18 57544377-57586702 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Distal tubular cells: 156.5;Erythroid cells: 479.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 32.7;K-562: 31.4;U-266/70: 33.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044100, HPA048177" Approved NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "HPA044100: AB_2678809, HPA048177: AB_2680300" "unprognostic (2.30e-1)" "unprognostic (3.17e-2)" "unprognostic (4.59e-3)" "unprognostic (6.85e-2)" "unprognostic (7.60e-2)" "unprognostic (1.08e-1)" "unprognostic (3.86e-2)" "unprognostic (3.34e-2)" "unprognostic (2.85e-2)" "unprognostic (2.43e-1)" "unprognostic (1.92e-1)" "unprognostic (2.36e-1)" "prognostic favorable (2.38e-10)" "unprognostic (1.10e-1)" "unprognostic (8.30e-2)" "unprognostic (4.05e-3)" "unprognostic (3.58e-2)" 9.3 14.7 5.2 1.9 6.3 39.6 8.8 4.7 6.3 7.8 5.8 10.0 1.8 9.2 2.9 12.0 7.6 2.6 17.0 4.8 5.2 20.9 22.0 6.5 1.9 6.3 5.3 8.4 9.2 4.3 8.9 3.2 7.2 9.5 2.4 3.6 9.0 2.4 32.2 8.4 7.2 2.8 5.3 10.0 8.4 4.7 5.3 5.0 9.7 7.4 1.8 9.9 8.5 9.7 5.3 15.1 4.3 8.2 2.6 7.4 4.2 4.5 3.4 2.9 4.0 7.3 3.0 4.8 4.3 6.8 3.9 3.5 4.2 3.8 3.7 6.6 19.0 29.5 12.8 10.5 4.9 17.7 32.7 5.4 4.0 4.0 1.4 4.2 5.3 8.0 31.4 10.9 2.1 10.1 7.8 3.8 4.3 1.9 8.7 6.3 19.7 4.7 8.6 19.1 2.5 8.4 4.8 7.4 3.4 2.5 4.6 2.8 6.8 3.3 1.9 1.4 3.2 33.4 12.4 6.3 3.5 5.6 3.9 3.7 3.8 8.1 4.5 5.0 3.2 2.4 3.0 4.9 6.6 1.0 2.8 3.3 0.6 6.9 5.2 4.3 3.2 3.8 5.2 6.3 4.7 6.3 4.8 5.2 6.3 5.3 7.2 5.3 5.3 9.7 4.9 6.4 10.6 10.4 5.6 2.5 6.7 8.6 5.2 3.8 7.8 6.1 24.5 15.7 7.2 5.5 4.2 36.6 15.4 6.7 156.5 16.4 0.4 6.6 7.9 7.3 2.4 479.7 20.3 16.3 16.5 10.3 4.6 9.7 16.5 11.8 4.2 26.3 33.4 8.4 14.6 4.1 8.2 10.6 4.9 1.1 9.9 12.7 1.8 12.2 15.4 15.1 9.2 12.1 45.5 12.4 6.4 7.2 12.5 6.5 7.0 18.2 9.8 4.1 0.0 9.0 6.8 4.1 5.5 14.2 3.1 24.2 8.1 19.1 5.7 5.0 FFAR2 "FFA2R, GPR43" ENSG00000126262 "Free fatty acid receptor 2" O15552 19 35443907-35451767 "G-protein coupled receptors, Predicted membrane proteins" "Immunity, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.3;lymphoid tissue: 22.2" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 24.1;Intestinal goblet cells: 8.9;Kupffer cells: 11.9;Macrophages: 15.4;Prostatic glandular cells: 7.7" "Cancer enhanced" "Detected in many" "prostate cancer: 6.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 25 "eosinophil: 85.0;neutrophil: 249.7" "Lineage enriched" "Detected in many" 38 "granulocytes: 249.7" "Cell line enhanced" "Detected in some" "HMC-1: 3.9;OE19: 1.8;SK-BR-3: 1.1;THP-1: 1.2;U-937: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA023985 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA023985: AB_1849302" "unprognostic (7.75e-3)" "unprognostic (5.65e-2)" "unprognostic (4.33e-3)" "unprognostic (1.68e-1)" "unprognostic (2.18e-1)" "unprognostic (2.55e-2)" "unprognostic (6.16e-2)" "unprognostic (2.04e-1)" "unprognostic (1.92e-2)" "unprognostic (9.04e-2)" "unprognostic (2.30e-2)" "unprognostic (4.60e-2)" "unprognostic (5.17e-4)" "unprognostic (1.48e-1)" "unprognostic (4.76e-2)" "unprognostic (9.42e-2)" "unprognostic (1.03e-2)" 4.9 0.3 0.2 17.8 0.4 20.3 2.3 0.2 0.4 0.2 0.6 0.8 3.3 0.1 0.0 1.3 1.0 1.4 1.0 0.2 0.2 0.3 1.5 7.5 0.1 0.4 0.4 0.0 0.6 0.3 0.1 1.6 0.5 1.1 0.7 0.1 0.7 0.0 0.2 1.1 4.6 1.3 0.2 22.2 1.2 0.0 0.4 0.7 0.4 3.7 0.7 6.0 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.6 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 1.1 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 3.1 2.1 85.0 0.0 5.6 0.0 0.1 0.0 0.0 0.9 0.2 0.0 0.0 249.7 0.0 6.5 0.1 0.0 0.7 0.2 0.4 0.2 0.4 0.2 0.2 0.4 0.4 0.5 0.2 0.4 0.8 5.6 0.0 3.2 0.0 0.6 0.1 0.4 0.3 0.0 0.0 0.2 0.3 0.4 0.0 2.7 0.0 0.0 0.0 0.3 0.3 0.0 0.3 0.2 0.0 0.1 0.8 24.1 0.0 0.0 0.0 0.1 1.4 0.0 0.0 5.1 0.0 0.4 0.0 5.0 0.0 0.0 8.9 2.0 11.9 2.6 0.1 0.0 15.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 7.7 1.1 0.0 2.2 0.0 0.0 0.4 2.4 0.1 0.2 0.0 0.6 0.1 1.3 0.1 0.6 1.5 FGF1 "AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-alpha, FGFA, GLIO703, HBGF1" ENSG00000113578 "Fibroblast growth factor 1" P05230 5 142592178-142698070 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 295.2;choroid plexus: 125.8" "Cell type enhanced" "Detected in many" "Astrocytes: 75.1;Cardiomyocytes: 62.4;Muller glia cells: 69.4;Oligodendrocytes: 119.8" "Cancer enriched" "Detected in many" 12 "glioma: 33.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 44.6;BJ hTERT+: 33.0;BJ hTERT+ SV40 Large T+: 35.9;BJ hTERT+ SV40 Large T+ RasG12V: 45.0;HBF TERT88: 64.3;hTEC/SVTERT24-B: 45.4;LHCN-M2: 30.6;U-2 OS: 33.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003265, CAB017519" Enhanced Supported Nucleoplasm "Secreted in other tissues" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "CAB017519: AB_629473, HPA003265: AB_1848522" "unprognostic (1.25e-2)" "unprognostic (2.43e-1)" "unprognostic (1.06e-1)" "unprognostic (3.41e-3)" "unprognostic (2.55e-2)" "unprognostic (3.52e-1)" "unprognostic (2.77e-1)" "unprognostic (2.39e-1)" "unprognostic (3.63e-1)" "unprognostic (1.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.54e-1)" "prognostic favorable (2.59e-5)" "unprognostic (3.72e-4)" "unprognostic (2.49e-1)" "prognostic favorable (3.45e-5)" "unprognostic (3.01e-4)" 17.9 3.3 206.3 1.6 259.3 1.1 12.5 213.9 295.2 1.3 125.8 2.4 1.0 3.1 7.9 2.0 1.7 2.5 50.2 183.5 245.5 66.5 1.7 2.8 1.2 236.2 237.7 0.9 0.8 4.3 6.5 2.1 259.9 1.8 1.3 18.8 7.3 2.3 2.2 1.7 1.2 2.5 225.4 6.9 0.8 2.0 244.3 1.5 5.6 7.8 2.0 1.2 1.0 272.8 5.6 0.3 0.3 1.5 1.1 3.3 1.8 44.6 33.0 35.9 45.0 0.2 0.2 1.3 3.1 15.4 2.1 0.7 0.0 3.5 64.3 0.2 0.0 0.0 0.8 0.4 0.6 0.0 0.4 1.6 1.1 45.4 2.7 9.7 0.0 0.2 0.0 1.6 30.6 0.7 0.1 0.9 1.4 0.1 1.4 0.2 1.5 0.6 1.5 0.2 1.1 2.3 0.1 0.9 0.6 8.0 0.0 0.2 1.1 5.8 33.0 0.8 21.3 0.8 0.4 0.3 8.2 0.3 1.6 0.0 0.0 0.4 0.4 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.1 0.3 0.3 0.0 0.1 0.2 0.1 0.0 206.3 259.3 213.9 295.2 183.5 245.5 236.2 237.7 259.9 225.4 244.3 272.8 1.4 0.0 0.0 75.1 0.1 0.4 5.0 5.7 7.4 3.5 1.2 25.4 62.4 0.0 2.1 20.2 16.7 1.1 0.1 0.0 0.0 1.1 0.4 0.0 0.7 4.8 0.0 0.0 13.0 0.0 0.5 4.7 0.0 0.2 0.0 0.0 1.1 0.0 0.1 0.0 14.6 0.0 12.2 0.0 0.0 1.4 0.0 0.2 3.6 29.0 0.0 69.4 0.0 15.1 119.8 0.6 0.0 0.4 0.0 5.3 0.0 0.3 0.1 11.6 6.6 0.5 23.4 0.1 0.1 0.6 0.0 0.8 0.4 0.0 0.0 0.7 FGGY FLJ10986 ENSG00000172456 "FGGY carbohydrate kinase domain containing" Q96C11 1 59296638-59810647 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 77.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 191.7;Cholangiocytes: 343.1;Hepatocytes: 142.3" "Cancer enhanced" "Detected in all" "liver cancer: 13.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 42.9;RH-30: 28.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054971, HPA075137" Approved "Nucleoplasm,Nuclear bodies" NA NA 220000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm "Nuclear bodies" "HPA054971: , HPA075137: " "unprognostic (4.15e-1)" "unprognostic (1.87e-1)" "unprognostic (2.31e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (2.20e-3)" "unprognostic (1.47e-3)" "unprognostic (1.80e-2)" "unprognostic (4.09e-1)" "unprognostic (2.78e-1)" "unprognostic (2.92e-1)" "unprognostic (1.47e-1)" "unprognostic (4.36e-3)" "unprognostic (7.22e-2)" "unprognostic (1.44e-1)" "unprognostic (2.70e-1)" "unprognostic (1.78e-1)" 4.2 14.6 10.5 2.0 12.8 2.3 6.6 21.8 10.2 6.3 4.5 7.1 7.1 4.7 36.5 5.5 9.9 5.4 11.3 7.4 12.1 19.1 77.1 4.7 3.3 12.9 13.4 4.8 12.0 10.5 9.7 3.0 12.9 7.8 6.7 9.6 7.5 10.3 41.8 5.7 8.1 4.2 9.3 2.8 6.1 4.2 16.5 4.1 7.7 17.1 3.6 7.0 5.2 12.7 4.8 1.4 9.2 3.9 4.7 16.6 0.8 4.1 6.8 2.3 3.4 0.0 3.8 5.4 13.0 11.0 4.1 2.0 1.6 11.9 4.9 42.9 1.1 3.8 2.9 8.6 12.3 2.3 2.4 23.2 10.2 5.0 7.9 10.0 4.6 6.0 2.7 3.4 15.3 5.2 3.0 3.2 5.8 13.0 5.3 6.5 28.3 2.1 12.9 8.8 7.2 3.2 5.6 3.3 12.0 8.0 2.8 2.3 4.7 4.0 2.6 4.7 2.8 7.5 2.9 4.6 12.9 9.2 3.8 1.5 1.3 1.4 3.0 1.3 2.7 5.1 1.4 3.8 2.2 3.6 2.7 4.3 2.2 2.9 3.4 1.1 2.8 1.8 10.5 12.8 21.8 10.2 7.4 12.1 12.9 13.4 12.9 9.3 16.5 12.7 3.7 54.5 191.7 83.2 7.9 20.9 23.8 45.2 14.2 10.1 33.1 66.9 29.9 343.1 40.4 12.9 12.5 9.3 3.7 4.2 17.6 62.6 14.0 33.2 7.5 6.9 2.4 12.2 20.4 42.5 4.5 7.6 7.1 20.4 10.1 5.3 5.3 142.3 11.4 8.4 33.7 11.3 22.4 8.8 7.6 11.4 1.8 6.7 35.6 17.8 11.2 12.2 3.1 39.2 36.0 17.7 7.7 3.0 3.4 19.1 14.9 47.9 91.2 16.4 0.0 31.4 8.9 4.6 11.5 13.5 31.5 4.5 5.1 5.9 17.1 35.5 FHL1 "bA535K18.1, FHL1B, FLH1A, KYO-T, MGC111107, SLIM1, XMPMA" ENSG00000022267 "Four and a half LIM domains 1" Q13642 X 136146702-136211359 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Emery-Dreifuss muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 11467.1;tongue: 9770.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1145.1;Early spermatids: 373.8;Late spermatids: 1206.9" "Cancer enhanced" "Detected in all" "renal cancer: 88.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 36.1" "Group enriched" "Detected in many" 4 "dendritic cells: 19.4;NK-cells: 36.1;T-cells: 18.2" "Cell line enhanced" "Detected in many" "BJ hTERT+: 303.7;fHDF/TERT166: 258.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001040, HPA001391, CAB020817" Enhanced Supported "Plasma membrane,Cytosol" NA NA 12000000 "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "Plasma membrane" "CAB020817: , HPA001040: AB_1848541, HPA001391: AB_1848542" "unprognostic (2.16e-1)" "unprognostic (5.13e-2)" "unprognostic (1.33e-2)" "unprognostic (1.89e-1)" "unprognostic (1.61e-3)" "unprognostic (1.76e-2)" "unprognostic (2.51e-2)" "unprognostic (9.34e-2)" "unprognostic (7.12e-3)" "unprognostic (1.20e-1)" "unprognostic (2.21e-3)" "unprognostic (1.72e-1)" "unprognostic (6.17e-3)" "unprognostic (4.04e-2)" "unprognostic (7.52e-2)" "unprognostic (2.05e-3)" "prognostic unfavorable (2.11e-4)" 938.4 65.8 120.8 75.5 117.2 11.7 441.8 95.9 126.3 315.5 85.8 672.0 83.2 464.6 107.7 538.1 281.6 127.6 1462.3 130.8 144.9 45.2 43.1 285.6 41.7 103.9 125.4 102.8 39.4 196.5 92.9 106.6 115.9 408.8 161.4 76.2 161.3 541.1 11467.1 101.3 235.5 486.5 114.8 43.0 368.4 60.2 130.1 25.1 310.1 9770.8 32.1 469.6 253.1 102.9 0.4 44.3 60.7 57.8 127.2 52.3 1.5 183.7 303.7 34.8 81.3 0.3 12.7 0.7 55.8 258.8 95.0 0.5 119.2 148.0 28.2 0.4 136.7 0.7 34.4 0.0 121.6 0.3 26.8 96.6 24.4 41.2 128.7 14.1 36.6 34.5 0.1 26.0 81.9 2.5 26.1 1.6 19.1 0.2 52.2 69.8 2.6 38.2 1.1 0.1 43.5 63.8 6.6 0.2 12.4 24.1 0.3 2.4 102.5 150.2 71.0 5.9 44.7 6.8 16.0 1.1 11.9 1.4 18.2 0.1 0.7 0.0 5.2 0.1 13.8 5.8 18.2 7.2 3.1 3.6 12.0 4.0 1.2 36.1 0.0 19.4 2.2 11.1 120.8 117.2 95.9 126.3 130.8 144.9 103.9 125.4 115.9 114.8 130.1 102.9 203.0 48.1 11.7 32.0 8.1 56.5 26.9 15.1 14.2 36.2 1.4 8.3 1145.1 0.0 4.9 11.0 8.4 0.6 8.6 0.5 1.9 3.0 373.8 4.3 32.3 61.1 13.8 17.9 70.2 0.2 1.1 236.0 2.0 2.0 15.8 41.0 113.6 6.1 4.3 99.3 55.6 0.8 0.0 5.1 47.0 1206.9 123.9 35.6 32.0 16.9 7.4 209.6 2.1 35.2 8.2 0.6 7.6 152.4 15.5 20.1 0.6 11.6 4.8 19.4 105.2 248.1 235.7 7.4 88.6 2.7 44.8 2.7 15.5 9.6 2.0 2.6 FHOD3 "FHOS2, FLJ22297, FLJ22717, KIAA1695" ENSG00000134775 "Formin homology 2 domain containing 3" Q2V2M9 18 36297714-36780055 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 172.8" "Cell type enhanced" "Detected in many" "Astrocytes: 104.5;Cone photoreceptor cells: 87.6;Excitatory neurons: 132.2;Granulosa cells: 84.9;Inhibitory neurons: 186.5;Oligodendrocyte precursor cells: 114.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 72.3;HDLM-2: 80.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021827, HPA024696" Uncertain "Intracellular and membrane" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA021827: AB_1848571, HPA024696: AB_1848573" "unprognostic (8.46e-2)" "unprognostic (8.76e-2)" "unprognostic (6.34e-2)" "unprognostic (3.44e-1)" "unprognostic (8.96e-2)" "unprognostic (8.30e-2)" "unprognostic (4.11e-4)" "unprognostic (2.73e-2)" "unprognostic (2.81e-1)" "unprognostic (2.44e-2)" "unprognostic (2.16e-3)" "unprognostic (4.55e-2)" "prognostic favorable (1.19e-5)" "unprognostic (1.64e-2)" "unprognostic (4.10e-2)" "unprognostic (3.00e-3)" "unprognostic (1.20e-1)" 3.4 32.1 13.2 2.4 14.3 0.1 6.1 8.7 17.7 5.6 13.9 14.5 1.6 3.0 42.2 9.4 11.2 7.2 172.8 13.8 12.3 23.2 1.4 1.5 1.3 37.9 15.1 6.9 2.1 1.0 10.5 1.3 36.8 27.9 3.4 36.1 11.3 62.8 49.5 6.5 5.5 10.1 11.5 1.3 3.2 4.1 8.5 2.4 3.6 20.5 4.0 14.6 5.2 13.5 15.5 5.4 34.3 8.2 0.2 0.0 2.6 34.1 72.3 6.7 6.5 0.0 24.5 2.8 8.9 16.3 19.2 19.5 11.4 14.8 4.0 80.1 4.0 0.0 1.0 0.1 0.4 0.0 1.1 4.5 7.1 3.6 1.5 36.6 0.2 0.0 0.0 0.2 8.0 0.0 0.1 0.2 7.5 0.0 4.9 0.0 0.0 18.9 32.5 17.0 19.0 44.6 7.4 0.1 4.6 3.0 0.2 0.1 39.6 21.3 1.6 0.9 29.5 31.8 0.0 0.0 23.8 0.0 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 14.3 8.7 17.7 13.8 12.3 37.9 15.1 36.8 11.5 8.5 13.5 0.4 0.0 0.0 104.5 0.0 3.2 0.9 8.9 14.8 6.5 2.3 11.4 38.0 0.0 2.7 12.9 87.6 0.1 0.0 0.2 3.9 1.3 1.7 10.2 1.7 0.6 0.0 0.4 132.2 0.9 11.3 7.9 1.1 0.6 0.0 84.9 0.0 0.0 0.2 0.0 186.5 0.2 6.1 0.0 0.6 0.4 0.0 0.3 10.6 11.2 0.0 7.3 0.0 114.1 3.4 3.3 0.1 0.4 0.0 0.6 0.0 7.9 15.3 33.6 0.0 11.2 6.3 2.2 2.8 1.6 0.6 0.4 0.4 29.9 0.3 0.3 FIBIN MGC24932 ENSG00000176971 "Fin bud initiation factor homolog" Q8TAL6 11 26994112-26997087 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 33.0;Fibroblasts: 80.8;Granulosa cells: 42.4;Leydig cells: 37.9;Oligodendrocyte precursor cells: 32.2;Peritubular cells: 35.0" "Cancer enhanced" "Detected in all" "glioma: 48.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 65.2;ASC TERT1: 41.8;fHDF/TERT166: 22.1;HHSteC: 88.2;HSkMC: 89.5;hTCEpi: 24.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040120 Uncertain "Intracellular and membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA040120: AB_10795243" "unprognostic (1.72e-1)" "unprognostic (2.61e-1)" "unprognostic (1.29e-1)" "unprognostic (9.04e-2)" "unprognostic (1.62e-2)" "unprognostic (5.42e-2)" "unprognostic (7.28e-2)" "unprognostic (1.03e-1)" "unprognostic (4.32e-2)" "unprognostic (5.08e-3)" "unprognostic (3.16e-2)" "unprognostic (2.20e-1)" "prognostic favorable (1.93e-5)" "prognostic unfavorable (6.72e-4)" "unprognostic (8.48e-2)" "prognostic unfavorable (1.85e-6)" "unprognostic (1.02e-2)" 32.3 4.9 11.0 7.7 10.6 0.0 25.1 11.4 10.8 35.6 6.1 27.8 2.2 26.1 8.0 11.3 35.7 7.9 32.6 10.8 10.7 15.2 2.0 27.2 2.8 10.6 12.7 18.5 3.8 0.3 2.6 12.6 11.7 17.0 2.6 0.6 17.6 61.3 17.1 16.7 12.0 17.1 11.4 14.1 21.1 1.3 11.6 2.1 13.4 14.5 0.9 16.3 58.3 11.7 0.0 0.0 1.0 0.0 65.2 41.8 0.1 2.1 5.7 0.2 0.9 0.0 0.0 0.0 0.0 22.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 88.2 0.0 0.0 89.5 24.0 1.1 0.0 1.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 4.2 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 10.6 11.4 10.8 10.8 10.7 10.6 12.7 11.7 11.4 11.6 11.7 2.5 0.0 0.0 17.9 0.0 6.6 1.6 33.0 1.8 0.3 1.9 0.9 1.2 11.5 4.0 11.0 0.0 1.2 0.0 0.1 11.7 0.6 0.1 0.0 0.1 1.0 0.0 0.0 0.5 0.0 0.9 80.8 0.0 0.0 0.0 42.4 6.1 0.5 1.8 0.0 0.1 0.0 12.2 0.0 10.3 0.3 37.9 0.8 7.2 0.0 0.0 19.8 0.0 32.2 0.1 0.1 0.0 35.0 0.1 0.2 0.0 4.3 0.9 0.6 0.0 3.7 7.4 0.1 0.3 0.8 5.1 1.9 0.5 3.9 0.0 0.0 FILIP1 "FILIP, KIAA1275" ENSG00000118407 "Filamin A interacting protein 1" Q7Z7B0 6 75291859-75493800 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 53.8;skeletal muscle: 35.8;tongue: 48.9" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 582.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.9;HUVEC TERT2: 1.7;RPTEC TERT1: 1.9;U-266/70: 6.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA053564 Enhanced Approved "Plasma membrane,Actin filaments" No NA "Cluster 38: Heart - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Actin filaments" "HPA053564: AB_2682192" "unprognostic (4.90e-2)" "unprognostic (3.77e-2)" "unprognostic (9.77e-3)" "unprognostic (3.83e-1)" "unprognostic (1.52e-1)" "unprognostic (4.98e-1)" "unprognostic (2.27e-2)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (5.17e-3)" "unprognostic (3.29e-2)" "unprognostic (2.23e-1)" "unprognostic (1.30e-3)" "unprognostic (3.97e-3)" "unprognostic (2.34e-1)" "unprognostic (4.65e-2)" "unprognostic (7.66e-3)" 6.8 1.5 1.5 2.9 1.8 0.2 2.4 0.1 2.5 1.8 0.7 11.7 1.8 8.5 0.9 9.5 4.8 5.7 53.8 4.1 0.5 1.8 3.2 7.6 1.2 0.2 0.5 1.3 1.4 12.4 1.4 5.1 0.3 3.9 3.3 0.4 1.2 3.4 35.8 0.6 2.6 13.2 0.5 0.3 3.2 2.1 0.8 1.1 2.3 48.9 0.9 10.9 1.6 1.5 0.0 1.3 0.2 0.1 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 6.9 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.2 0.0 0.0 0.1 0.1 0.9 0.0 0.1 0.0 0.0 1.7 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.4 0.1 0.1 0.0 0.1 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.9 0.7 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 1.5 1.8 0.1 2.5 4.1 0.5 0.2 0.5 0.3 0.5 0.8 1.5 82.1 128.2 82.6 5.9 0.5 0.6 0.5 2.8 0.0 3.5 0.5 0.8 582.5 0.0 9.1 0.0 0.0 0.8 0.5 0.1 1.9 0.1 54.2 18.2 1.7 45.9 0.0 2.7 9.7 0.4 0.3 60.3 0.0 19.2 1.3 1.7 72.1 0.7 1.3 0.0 12.8 0.1 8.2 1.9 1.2 17.6 2.5 1.8 1.8 5.6 0.0 2.5 1.0 6.0 10.0 0.0 0.0 4.5 0.0 0.8 0.4 0.1 62.4 3.5 92.1 70.2 114.2 7.1 7.9 0.7 0.9 0.8 1.8 11.9 0.1 0.4 FLT4 "PCL, VEGFR-3, VEGFR3" ENSG00000037280 "Fms related receptor tyrosine kinase 4" P35916 5 180601506-180649624 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 27.4;Endothelial cells: 27.1;Extravillous trophoblasts: 37.1;Hepatic stellate cells: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 3.8" "Lineage enriched" "Detected in single" 31 "T-cells: 3.8" "Cell line enhanced" "Detected in some" "AN3-CA: 10.1;BEWO: 12.4;HEK 293: 15.6;HL-60: 9.5;HUVEC TERT2: 9.9;JURKAT: 12.3;T-47d: 14.6;TIME: 15.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000099, HPA046519, HPA067906, HPA074389" Approved Supported "Nuclear speckles,Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 20000000 290000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles, Plasma membrane" "Cell Junctions" "CAB000099: , HPA046519: AB_2732527, HPA067906: AB_2732775, HPA074389: " "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" "unprognostic (9.45e-3)" "unprognostic (3.81e-1)" "unprognostic (9.26e-2)" "unprognostic (3.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-1)" "unprognostic (1.88e-2)" "unprognostic (9.41e-3)" "unprognostic (1.83e-1)" "unprognostic (8.26e-2)" "unprognostic (1.32e-1)" 17.2 11.3 3.5 4.7 4.6 0.8 14.7 2.6 3.4 9.0 2.6 4.9 2.8 8.0 3.0 4.4 9.8 3.8 9.7 5.1 2.6 20.1 6.2 16.9 5.5 3.4 3.0 4.5 2.0 2.3 7.8 6.4 3.6 5.6 1.3 0.3 2.0 2.5 4.7 4.0 7.2 4.1 2.8 17.6 3.5 3.1 4.2 1.0 25.7 4.1 1.4 5.6 5.5 2.7 0.1 2.5 3.2 10.1 0.0 0.0 12.4 0.3 0.1 0.0 0.0 0.4 0.3 0.3 0.9 0.1 0.6 0.4 3.4 0.2 0.3 0.1 15.6 1.2 0.5 0.5 0.1 9.5 0.3 0.2 0.1 0.2 0.4 0.3 9.9 12.3 0.4 0.4 2.1 5.6 0.1 0.5 7.0 0.3 0.6 8.2 0.1 0.1 0.1 0.3 0.3 1.1 0.1 0.2 0.1 3.1 14.6 0.3 15.7 0.2 6.9 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.5 0.0 3.8 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 3.5 4.6 2.6 3.4 5.1 2.6 3.4 3.0 3.6 2.8 4.2 2.7 27.4 0.0 1.7 0.7 0.7 0.9 0.2 0.0 1.2 0.2 1.4 1.4 4.5 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.1 27.1 0.0 0.0 0.2 0.0 37.1 0.8 0.0 0.1 2.5 2.4 64.6 0.6 1.2 0.0 0.1 0.0 0.0 3.3 0.8 0.7 0.3 0.6 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.7 0.7 0.1 5.2 0.1 1.1 1.0 1.8 0.2 0.0 0.1 FN3K ENSG00000167363 "Fructosamine 3 kinase" Q9H479 17 82735615-82751196 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 79.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 90.1;Proximal tubular cells: 167.2;Rod photoreceptor cells: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 34.3;Hep G2: 66.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059151, HPA061358" Supported Approved Mitochondria NA NA 180000 "Cluster 35: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA059151: AB_2683931, HPA061358: AB_2684490" "unprognostic (4.74e-2)" "unprognostic (9.19e-2)" "unprognostic (4.22e-2)" "prognostic favorable (1.10e-4)" "unprognostic (6.10e-2)" "unprognostic (1.39e-1)" "unprognostic (6.45e-2)" "unprognostic (9.86e-2)" "unprognostic (5.08e-2)" "unprognostic (2.61e-1)" "prognostic favorable (2.40e-4)" "unprognostic (6.66e-2)" "prognostic favorable (1.39e-6)" "unprognostic (2.68e-2)" "unprognostic (8.02e-2)" "unprognostic (4.77e-1)" "unprognostic (1.22e-2)" 14.4 47.3 47.4 2.9 64.3 12.0 8.4 64.4 56.6 10.4 36.8 15.5 22.4 9.4 7.0 4.6 12.5 6.9 47.5 46.5 54.3 49.6 48.1 7.8 2.4 63.3 56.8 22.3 18.1 21.9 22.4 5.3 62.7 12.5 9.5 13.8 28.5 12.1 23.5 5.3 14.5 6.6 49.4 4.6 17.4 5.2 55.6 1.0 10.2 10.9 2.3 8.8 7.9 79.8 1.3 16.1 4.4 23.2 6.9 5.7 2.9 2.9 2.2 5.4 2.7 21.0 3.3 0.2 3.9 2.6 4.5 0.6 34.3 2.5 2.0 1.0 2.4 12.5 12.9 66.2 18.8 0.3 10.1 4.9 9.0 2.1 0.0 5.7 10.6 1.0 22.4 0.6 1.1 1.8 0.2 0.2 2.9 7.6 13.0 2.1 0.3 0.1 11.5 4.5 7.0 22.7 5.3 1.2 15.8 3.8 15.4 4.5 2.5 0.4 1.6 5.6 4.3 1.2 0.3 0.1 0.4 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.4 64.3 64.4 56.6 46.5 54.3 63.3 56.8 62.7 49.4 55.6 79.8 3.9 3.2 2.0 8.8 1.9 1.5 3.7 1.5 14.8 41.9 4.5 3.7 5.8 4.3 2.5 31.3 47.9 11.7 2.6 5.7 90.1 3.2 0.2 11.6 3.0 5.2 5.4 49.2 10.2 1.2 2.6 8.6 47.9 25.9 1.3 6.9 4.2 5.4 8.2 32.0 13.0 10.4 6.1 1.0 3.4 0.4 5.3 5.7 12.4 5.6 1.2 36.2 1.0 6.0 17.1 1.7 7.3 3.0 9.1 3.9 28.2 167.2 2.5 72.9 0.0 6.1 9.8 0.8 4.1 12.8 1.8 8.3 3.1 18.6 9.5 3.5 FOLR2 FRβ ENSG00000165457 "Folate receptor beta" P14207 11 72216601-72221950 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Transport Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 168.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 1114.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 64.2;intermediate monocyte: 50.6" "Group enriched" "Detected in many" 4 "dendritic cells: 18.7;monocytes: 64.2" "Cell line enriched" "Detected in some" 5 "U-698: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 15000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (2.03e-1)" "unprognostic (6.58e-3)" "prognostic unfavorable (8.42e-4)" "unprognostic (1.47e-1)" "unprognostic (2.76e-1)" "unprognostic (2.83e-1)" "unprognostic (1.39e-1)" "unprognostic (3.36e-1)" "unprognostic (3.38e-1)" "unprognostic (2.51e-1)" "unprognostic (8.11e-2)" "unprognostic (1.16e-1)" "unprognostic (3.91e-3)" "unprognostic (6.16e-3)" "unprognostic (1.14e-1)" "prognostic favorable (8.41e-4)" "unprognostic (7.98e-3)" 119.1 55.0 10.7 28.2 11.0 10.8 31.7 8.2 18.6 27.9 13.8 36.0 19.5 13.5 12.4 31.6 16.8 80.1 38.6 10.9 9.5 10.8 44.8 39.7 78.5 9.3 10.7 16.0 7.1 7.9 6.1 168.4 11.4 6.1 46.7 0.2 12.8 16.7 5.9 9.8 29.6 46.3 9.3 27.7 21.0 13.0 16.2 28.7 9.1 26.3 29.0 81.3 6.3 16.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.7 0.2 0.2 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.2 0.0 0.2 0.0 18.6 0.5 0.8 0.0 0.0 64.2 0.0 0.3 50.6 0.0 9.5 0.0 0.0 18.7 4.0 0.0 0.0 1.1 1.8 13.7 0.2 0.0 20.4 10.7 11.0 8.2 18.6 10.9 9.5 9.3 10.7 11.4 9.3 16.2 16.1 3.4 0.0 0.6 0.0 8.0 7.9 0.1 0.0 1.2 0.0 0.1 1.1 2.2 1.5 0.0 0.0 0.0 7.6 0.6 0.0 0.0 0.0 0.9 0.3 0.1 2.3 0.0 0.0 0.0 0.0 6.0 2.4 0.0 0.5 2.5 0.0 2.2 1.7 1114.8 0.0 0.0 0.0 0.0 229.3 98.8 2.5 1.5 199.4 0.0 15.9 5.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 2.1 0.1 0.0 0.2 0.0 0.3 0.0 2.5 1.2 0.6 0.7 1.3 5.1 16.0 1.2 0.1 0.0 0.1 FRAT1 ENSG00000165879 "FRAT regulator of WNT signaling pathway 1" Q92837 10 97319271-97321915 "Predicted intracellular proteins" "Wnt signaling pathway" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 25.2;Early spermatids: 31.3;Kupffer cells: 26.1;Late spermatids: 85.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 8.7;neutrophil: 10.1" "Lineage enriched" "Detected in many" 5 "granulocytes: 10.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB046472, HPA055258" Approved Approved Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 6: T47d - Mammary gland" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Cytosol" "CAB046472: AB_1849131, HPA055258: AB_2682763" "unprognostic (1.48e-2)" "prognostic favorable (5.92e-4)" "unprognostic (3.54e-1)" "unprognostic (1.13e-2)" "unprognostic (1.45e-1)" "prognostic favorable (2.75e-4)" "unprognostic (1.11e-2)" "unprognostic (4.44e-3)" "unprognostic (5.73e-2)" "unprognostic (2.50e-2)" "unprognostic (6.36e-3)" "unprognostic (1.89e-1)" "prognostic favorable (6.36e-5)" "unprognostic (6.38e-2)" "unprognostic (5.27e-2)" "unprognostic (4.31e-2)" "unprognostic (1.43e-2)" 3.2 2.9 2.6 5.0 2.6 10.6 2.4 3.8 3.5 2.5 1.8 3.2 4.4 2.6 1.0 2.4 3.0 1.2 3.1 2.8 3.1 2.1 11.8 3.3 3.8 3.6 3.4 2.4 3.9 2.0 2.1 1.2 3.1 4.0 1.9 1.9 3.7 1.6 3.8 4.2 4.5 1.5 2.9 12.6 4.8 10.9 3.9 4.1 2.0 2.6 2.4 2.3 2.1 2.6 0.7 1.3 1.4 6.7 1.8 0.9 1.5 0.8 2.9 0.5 0.6 0.2 0.8 4.5 1.5 0.5 1.0 2.0 1.1 1.4 0.1 4.0 2.0 3.8 0.8 1.8 0.6 1.4 4.0 0.8 2.0 0.2 0.9 2.7 1.2 6.1 1.6 3.1 0.4 4.2 4.0 7.9 1.9 4.8 5.5 3.3 0.3 2.9 0.5 1.0 0.7 2.2 1.0 2.1 1.5 1.4 7.7 5.4 1.1 0.3 0.4 1.0 0.3 2.9 1.7 1.5 0.5 7.0 0.0 0.9 2.0 8.7 0.5 1.3 0.4 0.5 0.4 0.7 1.0 0.5 0.7 0.5 10.1 0.2 1.5 0.6 0.3 0.5 2.6 2.6 3.8 3.5 2.8 3.1 3.6 3.4 3.1 2.9 3.9 2.6 4.1 3.2 5.8 1.0 5.8 1.1 1.1 0.9 1.2 25.2 2.9 1.9 3.3 5.7 0.9 1.8 0.0 0.6 16.8 6.0 0.0 1.4 31.3 5.8 1.6 4.0 4.2 4.2 0.7 2.0 1.7 1.5 2.0 4.1 0.0 5.0 3.3 15.6 3.9 3.3 1.6 4.9 4.1 26.1 1.8 85.2 1.2 15.5 3.6 0.0 12.5 4.9 13.4 0.5 0.7 1.1 2.3 1.9 1.1 2.5 3.8 1.0 3.3 8.4 0.0 3.4 1.7 1.2 0.6 1.6 1.6 2.3 9.0 4.7 2.8 2.2 FRMD7 "FLJ43346, NYS, NYS1" ENSG00000165694 "FERM domain containing 7" Q6ZUT3 X 132076990-132128020 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Neurogenesis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "endometrium 1: 2.9;kidney: 2.7;smooth muscle: 2.2" "Cell type enriched" "Detected in single" 19 "Distal tubular cells: 9.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-87 MG: 1.5" "Region enriched" "Detected in many" 28 "olfactory bulb: 65.7" "Region enriched" "Detected in single" 86 "olfactory bulb: 21.3" HPA000886 Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cytosol" Nucleoplasm "HPA000886: AB_1079269" "unprognostic (3.08e-2)" "unprognostic (1.27e-1)" "unprognostic (1.36e-1)" "unprognostic (3.07e-1)" "unprognostic (4.02e-2)" "unprognostic (1.64e-2)" "unprognostic (2.28e-1)" "unprognostic (2.18e-2)" "unprognostic (3.84e-1)" "unprognostic (3.54e-2)" "unprognostic (3.00e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.0 0.0 2.9 0.5 0.0 0.5 0.0 0.1 0.1 0.1 2.7 0.4 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 0.2 0.0 2.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FRZB "FRE, FRITZ, FRP-3, FRZB-1, FRZB-PEN, FRZB1, FZRB, hFIZ, SFRP3, SRFP3" ENSG00000162998 "Frizzled related protein" Q92765 2 182833275-182866637 "Disease related genes, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 336.9" "Cell type enriched" "Detected in many" 13 "Muller glia cells: 3633.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 19.2;ASC diff: 9.4;NTERA-2: 7.4;SH-SY5Y: 6.5" "Region enhanced" "Detected in all" "olfactory bulb: 56.9" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA 44000 "Cluster 19: B-cells - Humoral immune response" "Cluster 79: Retina - Phototransduction" "Cluster 12: NES - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (5.39e-2)" "unprognostic (1.48e-2)" "unprognostic (1.18e-1)" "unprognostic (1.79e-2)" "unprognostic (1.93e-1)" "unprognostic (2.09e-3)" "unprognostic (1.64e-2)" "unprognostic (2.38e-2)" "unprognostic (4.67e-2)" "unprognostic (8.58e-2)" "unprognostic (5.41e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (8.97e-6)" "unprognostic (3.53e-2)" "unprognostic (1.05e-2)" "unprognostic (6.04e-2)" "unprognostic (3.21e-1)" 10.4 5.7 10.4 6.1 12.8 0.7 12.6 11.0 18.6 20.3 52.2 16.2 14.4 17.2 11.4 12.4 7.1 39.0 19.9 10.3 11.2 16.3 3.3 9.1 18.7 14.1 10.9 13.5 7.1 6.7 18.6 30.5 15.4 12.9 19.9 336.9 4.7 16.6 26.6 10.4 14.5 31.1 11.9 88.9 21.9 14.2 11.3 4.9 10.8 116.2 11.9 10.3 12.3 10.3 0.0 0.0 19.2 0.2 9.4 0.2 0.2 0.0 0.9 3.2 2.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.4 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.8 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 7.4 0.0 0.0 0.6 0.8 0.0 0.0 0.0 1.0 6.5 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 12.8 11.0 18.6 10.3 11.2 14.1 10.9 15.4 11.9 11.3 10.3 13.8 0.0 0.5 1.0 0.8 8.2 0.4 0.2 0.6 39.8 7.8 18.7 2.9 0.0 1.4 0.0 33.3 5.3 0.5 2.1 0.0 0.1 0.3 0.5 1.4 18.5 1.2 0.0 2.7 8.2 3.8 97.8 9.7 0.9 0.0 0.5 3.6 1.0 7.8 26.9 7.7 137.4 0.0 0.8 3.7 2.8 3.7 0.5 245.5 25.3 0.0 3633.8 0.0 8.5 1.7 0.2 0.8 14.7 5.8 1.8 1.3 0.2 0.2 124.4 276.1 41.9 157.1 0.2 0.1 0.6 3.1 12.4 1.5 22.9 3.4 0.6 FTCDNL1 FONG ENSG00000226124 "Formiminotransferase cyclodeaminase N-terminal like" E5RQL4 2 199760544-199851192 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 39.8;Excitatory neurons: 43.5;Oligodendrocytes: 115.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA065748 Approved Vesicles "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA065748: " "unprognostic (1.78e-1)" "unprognostic (1.70e-1)" "unprognostic (1.27e-2)" "unprognostic (9.80e-2)" "unprognostic (3.09e-1)" "unprognostic (7.21e-2)" "unprognostic (1.54e-3)" "unprognostic (1.59e-1)" "unprognostic (1.03e-1)" "unprognostic (4.82e-2)" "unprognostic (5.37e-2)" "unprognostic (9.86e-2)" "prognostic favorable (3.31e-4)" "unprognostic (3.92e-2)" "unprognostic (4.63e-2)" "prognostic unfavorable (5.74e-4)" "unprognostic (1.21e-2)" 2.4 4.9 4.4 0.9 7.9 2.3 2.1 5.4 5.5 0.6 1.8 1.1 1.0 0.4 1.8 1.3 1.9 0.9 2.9 4.5 4.8 4.2 10.0 1.4 2.0 6.1 6.7 1.0 2.2 1.5 0.9 0.6 5.7 1.2 1.1 1.4 2.4 0.6 8.1 1.2 0.8 1.1 6.1 4.6 0.9 1.0 6.0 0.7 5.7 8.4 0.8 0.7 0.9 7.6 0.6 1.9 0.1 0.0 1.9 1.1 1.4 0.7 0.7 1.0 0.4 0.0 3.5 2.0 0.2 0.8 5.7 0.0 0.9 5.3 1.2 2.3 0.5 1.5 0.8 1.7 0.7 5.5 6.5 0.8 0.2 0.4 0.1 0.7 0.0 4.9 2.7 0.1 0.7 6.0 1.9 2.1 1.6 0.5 4.0 0.3 0.2 0.0 0.4 0.0 2.3 0.0 3.4 3.2 3.2 1.3 4.8 7.1 0.6 2.7 0.0 1.8 1.1 4.7 2.9 1.1 5.2 2.7 1.3 0.0 4.1 1.7 0.4 5.5 1.7 3.4 1.7 0.6 5.8 2.1 1.1 1.8 0.0 1.1 5.1 8.7 0.0 1.4 4.4 7.9 5.4 5.5 4.5 4.8 6.1 6.7 5.7 6.1 6.0 7.6 0.8 0.0 0.0 39.8 3.2 2.7 2.9 0.0 13.6 3.3 6.2 5.5 5.7 4.3 1.3 3.7 4.2 1.5 3.3 0.3 1.9 0.2 2.4 8.4 0.8 1.5 0.0 5.9 43.5 0.7 1.4 1.4 4.6 3.3 0.0 5.9 2.2 6.9 7.4 1.7 23.5 1.2 0.0 8.1 4.7 1.0 0.3 8.2 7.2 17.8 2.1 1.7 0.0 24.6 115.4 0.3 0.1 0.4 1.4 2.6 1.0 10.6 0.0 6.5 0.0 2.4 3.4 0.4 2.0 6.9 2.3 0.3 1.5 10.3 1.1 1.2 FXYD1 PLM ENSG00000266964 "FXYD domain containing ion transport regulator 1" O00168 19 35138824-35143109 "Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1381.3;tongue: 838.7" "Cell type enhanced" "Detected in many" "Fibroblasts: 225.1;Hepatocytes: 651.7;Leydig cells: 430.3;Muller glia cells: 343.4;Skeletal myocytes: 188.7;Smooth muscle cells: 205.7" "Cancer enriched" "Detected in many" 5 "liver cancer: 8.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 11.0" "Group enriched" "Detected in many" 4 "B-cells: 11.0;T-cells: 6.9" "Cell line enhanced" "Detected in some" "ASC diff: 46.7;ASC TERT1: 13.5;HSkMC: 19.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026873 Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 43: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" Nucleoli "HPA026873: AB_1855471" "unprognostic (5.58e-3)" "unprognostic (6.60e-2)" "unprognostic (3.37e-2)" "unprognostic (1.31e-2)" "prognostic unfavorable (6.91e-4)" "unprognostic (1.54e-2)" "unprognostic (1.72e-2)" "unprognostic (3.54e-3)" "unprognostic (8.13e-2)" "unprognostic (5.11e-2)" "unprognostic (8.64e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (7.59e-8)" "unprognostic (9.97e-3)" "unprognostic (2.25e-1)" "unprognostic (1.65e-1)" "unprognostic (1.92e-2)" 141.4 26.1 496.5 9.6 528.9 2.2 125.1 506.1 637.3 291.9 616.5 168.3 14.3 173.3 62.1 70.7 187.3 56.3 557.7 487.5 503.4 28.6 558.7 85.8 6.6 568.0 515.0 144.7 19.2 3.8 39.8 29.3 494.8 116.0 25.6 35.9 37.2 73.5 1381.3 48.3 67.2 104.5 511.1 20.8 72.6 12.1 560.2 8.2 38.0 838.7 6.7 80.0 194.9 498.6 1.1 0.0 0.0 0.2 46.7 13.5 1.3 5.7 0.1 0.0 0.0 0.0 0.3 3.8 1.5 0.0 0.1 1.0 1.1 0.7 0.0 3.4 1.3 0.7 0.0 1.9 5.2 0.3 0.4 19.3 0.0 0.1 0.5 0.5 0.2 0.1 1.0 3.7 0.1 0.0 0.1 0.8 0.2 2.8 0.6 0.0 0.2 1.1 0.0 0.0 0.3 0.2 0.7 0.2 1.8 0.3 0.2 6.1 0.5 0.1 0.5 0.4 0.0 0.1 0.0 0.4 0.9 0.6 7.7 1.6 0.3 0.0 1.3 0.7 0.8 11.0 3.6 1.5 0.3 6.9 0.7 0.9 0.5 2.1 0.8 0.6 6.9 0.6 496.5 528.9 506.1 637.3 487.5 503.4 568.0 515.0 494.8 511.1 560.2 498.6 46.1 0.0 0.0 44.4 15.8 29.4 3.7 2.7 8.0 1.8 4.4 18.0 0.3 11.5 0.8 25.8 4.2 1.2 9.5 42.2 0.0 0.1 1.9 2.2 47.4 13.3 0.0 8.4 3.7 4.9 1.6 225.1 2.0 1.2 0.0 0.1 36.0 651.7 4.4 0.0 0.4 0.8 2.0 14.4 49.0 12.0 430.3 5.3 53.4 2.8 1.0 343.4 1.0 1.5 0.5 1.1 5.3 128.2 2.5 3.3 0.4 0.2 12.6 8.6 118.3 188.7 205.7 10.7 21.7 3.0 27.3 2.9 18.8 0.1 0.7 2.5 FYB2 "ARAP, C1orf168, FLJ43208, RP4-758N20.2" ENSG00000187889 "FYN binding protein 2" Q5VWT5 1 56718789-56819696 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 14.5;fallopian tube: 13.7;liver: 17.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 22.4;Collecting duct cells: 31.3;Endometrial ciliated cells: 11.1;Glandular and luminal cells: 10.8;Respiratory ciliated cells: 48.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "hippocampal formation: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 19 "T-47d: 5.1" "Region enhanced" "Detected in single" "hippocampal formation: 2.1" "Low region specificity" "Detected in some" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (6.12e-5)" "unprognostic (1.78e-1)" "unprognostic (1.14e-1)" "unprognostic (1.58e-1)" "unprognostic (3.35e-2)" "unprognostic (3.89e-2)" "unprognostic (9.19e-3)" "unprognostic (4.77e-3)" "unprognostic (1.29e-2)" "unprognostic (2.02e-2)" "unprognostic (3.71e-1)" "unprognostic (2.86e-4)" "unprognostic (3.84e-2)" "unprognostic (2.50e-1)" "unprognostic (1.08e-1)" "unprognostic (1.04e-3)" 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.0 3.6 14.5 0.2 0.3 0.9 0.3 0.2 13.7 0.0 1.5 1.0 0.1 3.5 17.1 2.0 0.0 0.0 0.0 0.1 1.0 6.3 0.8 0.0 0.0 1.5 0.4 0.0 2.1 1.7 1.5 0.0 0.6 0.0 0.0 0.0 0.4 1.3 0.1 2.5 0.3 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 22.4 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 6.3 0.0 0.0 6.8 31.3 0.0 0.5 0.0 0.0 3.9 0.5 0.0 11.1 0.7 0.0 0.0 0.0 0.0 1.5 0.0 7.3 0.0 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 48.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 GADD45A "DDIT1, GADD45" ENSG00000116717 "Growth arrest and DNA damage inducible alpha" P24522 1 67685201-67688334 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, Growth arrest" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 240.5" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 858.9;Basal prostatic cells: 2807.1;Glandular and luminal cells: 982.6;Urothelial cells: 1740.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 48.4" "Group enriched" "Detected in all" 5 "granulocytes: 48.4;T-cells: 18.6" "Cell line enhanced" "Detected in all" "HHSteC: 365.9;hTERT-HME1: 577.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053420 Supported "Nuclear speckles" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" "HPA053420: AB_2682144" "unprognostic (1.36e-2)" "unprognostic (3.29e-2)" "unprognostic (9.58e-2)" "unprognostic (3.76e-3)" "unprognostic (5.81e-2)" "unprognostic (1.36e-2)" "unprognostic (1.57e-3)" "unprognostic (2.80e-3)" "unprognostic (1.42e-1)" "unprognostic (6.26e-2)" "unprognostic (3.43e-2)" "unprognostic (5.21e-2)" "prognostic favorable (8.06e-6)" "unprognostic (6.11e-2)" "unprognostic (2.89e-1)" "unprognostic (3.43e-3)" "unprognostic (1.93e-1)" 122.0 15.9 21.0 20.0 24.7 136.2 83.7 19.2 27.5 65.6 22.3 29.6 24.8 69.5 23.3 39.2 42.3 44.2 62.2 20.8 24.0 147.2 164.9 75.0 13.7 34.7 26.8 49.6 20.2 19.5 19.1 22.2 24.6 25.6 21.2 19.0 32.4 36.9 240.5 57.9 32.2 38.3 18.6 26.8 53.2 12.3 25.3 30.7 73.8 26.4 16.8 50.4 44.4 28.7 138.6 9.7 22.3 7.5 44.8 43.9 219.8 239.5 122.6 88.5 96.7 50.8 25.3 61.1 71.4 42.0 206.6 85.3 3.0 219.6 164.5 44.9 23.6 75.7 24.0 51.8 365.9 22.5 7.5 76.7 117.8 107.7 577.7 41.5 61.0 15.2 165.6 109.9 104.5 4.8 7.2 27.3 29.8 19.3 96.3 16.4 177.2 67.9 44.2 110.5 102.7 17.1 51.9 15.2 158.3 79.7 2.6 23.2 61.6 85.7 111.6 89.3 165.7 267.3 54.9 106.8 37.8 11.1 86.3 23.6 5.7 48.4 6.3 2.8 5.3 2.3 4.4 5.3 2.6 1.5 1.2 2.0 8.2 6.5 2.0 4.1 18.6 8.7 21.0 24.7 19.2 27.5 20.8 24.0 34.7 26.8 24.6 18.6 25.3 28.7 402.5 64.1 19.0 6.8 51.2 858.9 2807.1 273.2 225.3 45.1 56.7 100.6 190.5 47.1 155.8 103.0 10.4 24.6 85.1 175.3 236.7 264.4 1.6 410.7 250.6 176.6 131.7 116.2 6.1 253.6 117.8 177.0 87.7 982.6 44.5 18.9 74.6 110.1 18.6 26.9 7.0 99.6 122.1 23.5 290.6 4.0 38.2 94.7 158.3 7.5 273.2 30.3 12.3 6.6 1.0 367.3 202.0 64.7 116.8 786.2 101.4 530.0 135.1 72.8 52.6 136.0 201.6 3.7 18.8 365.2 390.8 17.6 139.5 88.6 70.3 1740.4 GALK1 GALK ENSG00000108479 "Galactokinase 1" P51570 17 75751594-75765236 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Galactose metabolism" "Kinase, Transferase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 126.4" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 100.1;Hepatocytes: 116.7;Proximal enterocytes: 139.4;Proximal tubular cells: 122.0" "Cancer enhanced" "Detected in all" "liver cancer: 42.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007094, HPA016960" Approved Approved "Golgi apparatus,Cytosol" NA NA 57000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "Golgi apparatus" "HPA007094: AB_1078939, HPA016960: AB_1849430" "unprognostic (1.16e-1)" "unprognostic (1.33e-2)" "unprognostic (1.81e-2)" "unprognostic (2.94e-2)" "unprognostic (1.00e-1)" "unprognostic (2.21e-1)" "unprognostic (1.29e-1)" "unprognostic (7.82e-2)" "unprognostic (2.26e-1)" "unprognostic (7.04e-2)" "unprognostic (1.06e-1)" "unprognostic (2.35e-2)" "prognostic unfavorable (1.55e-6)" "unprognostic (3.04e-1)" "unprognostic (1.71e-1)" "unprognostic (2.77e-1)" "prognostic unfavorable (1.62e-5)" 18.6 12.5 5.9 7.8 6.7 5.6 17.1 6.4 8.4 17.5 5.9 12.5 20.6 16.5 1.0 24.4 14.9 4.3 19.7 6.0 6.6 32.0 126.4 18.7 7.4 7.9 6.3 13.7 31.2 10.6 5.7 5.8 7.5 13.3 2.0 0.7 20.0 5.7 8.6 20.6 18.3 3.9 7.0 24.5 17.6 16.0 6.8 6.1 11.6 3.6 3.4 13.0 17.8 8.2 20.4 65.2 4.9 20.7 6.8 16.6 16.7 16.9 14.3 16.8 15.8 35.4 4.2 31.2 19.5 9.3 12.6 11.9 5.0 4.4 1.9 14.2 39.3 20.1 25.1 62.4 22.1 13.0 41.9 15.3 6.9 8.5 3.5 8.5 39.1 16.9 15.9 21.2 11.7 77.3 38.6 44.7 4.7 9.8 32.3 43.6 50.1 50.9 9.8 7.3 9.9 26.1 14.6 35.8 35.0 3.8 29.8 20.9 33.4 24.3 22.3 21.7 14.6 44.4 12.4 8.2 26.7 30.3 18.3 7.2 77.2 23.0 23.0 67.8 20.8 27.7 18.5 21.2 70.1 18.9 10.0 14.5 53.1 16.2 55.6 93.3 23.6 40.8 5.9 6.7 6.4 8.4 6.0 6.6 7.9 6.3 7.5 7.0 6.8 8.2 42.1 16.0 12.9 3.3 17.7 8.7 10.0 4.4 7.4 7.3 22.4 20.6 22.6 22.8 10.6 12.9 0.0 48.4 16.3 8.4 68.4 28.5 1.3 4.9 24.5 23.5 8.4 9.0 1.5 55.2 100.1 25.3 10.2 8.6 27.9 16.6 29.3 116.7 56.1 3.3 1.7 20.9 22.4 49.0 25.2 5.6 31.1 33.3 39.2 0.0 42.3 19.2 20.6 2.5 1.6 19.3 49.6 24.0 29.1 5.7 139.4 122.0 4.0 6.1 6.6 19.2 20.8 1.7 22.1 16.6 12.5 42.3 14.9 6.1 28.2 9.2 GALNT16 "GalNAc-T16, GALNTL1, KIAA1130" ENSG00000100626 "Polypeptide N-acetylgalactosaminyltransferase 16" Q8N428 14 69259277-69357033 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.8;heart muscle: 45.0" "Cell type enhanced" "Detected in many" "Astrocytes: 16.6;Cardiomyocytes: 46.7;Excitatory neurons: 27.6;Fibroblasts: 24.0;Inhibitory neurons: 23.8;Smooth muscle cells: 14.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.5;ASC diff: 11.7;hTEC/SVTERT24-B: 17.0;hTERT-RPE1: 17.2;SCLC-21H: 8.7;U-2 OS: 19.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059136, HPA075325" Approved Approved Vesicles,Cytosol NA NA 370000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Cytosol" "HPA059136: AB_2683919, HPA075325: " "unprognostic (9.71e-3)" "unprognostic (7.47e-2)" "unprognostic (4.02e-1)" "unprognostic (2.30e-2)" "unprognostic (6.71e-2)" "unprognostic (5.72e-3)" "unprognostic (3.18e-3)" "unprognostic (1.22e-1)" "unprognostic (1.02e-1)" "unprognostic (1.28e-2)" "unprognostic (3.62e-4)" "unprognostic (1.31e-2)" "prognostic favorable (5.23e-6)" "unprognostic (5.38e-3)" "unprognostic (3.34e-2)" "unprognostic (3.93e-2)" "unprognostic (7.96e-5)" 14.4 11.6 25.7 2.0 24.4 0.1 12.0 14.7 28.4 7.6 6.5 6.5 2.2 7.3 2.8 3.6 5.6 3.4 45.0 27.0 35.5 7.7 2.0 3.4 3.2 19.6 22.5 2.1 4.3 2.5 4.7 0.4 19.9 4.0 2.2 1.3 23.5 4.6 4.4 7.5 3.7 8.6 16.4 12.1 3.2 3.5 40.8 2.2 4.9 5.8 1.3 3.1 5.0 21.3 0.0 0.8 8.5 0.3 11.7 5.3 0.0 1.3 0.1 1.5 2.3 0.4 0.0 0.0 0.2 1.4 0.8 0.0 3.0 0.0 0.3 0.1 6.0 0.0 0.2 0.5 0.1 0.0 0.5 0.5 0.0 17.0 0.0 17.2 0.9 0.0 0.0 0.0 2.8 0.5 0.0 0.0 1.7 0.0 0.1 0.0 4.8 0.0 0.5 0.0 8.7 3.0 1.8 0.4 0.0 0.3 0.3 0.0 0.1 1.7 19.9 2.2 2.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.7 24.4 14.7 28.4 27.0 35.5 19.6 22.5 19.9 16.4 40.8 21.3 4.0 0.0 0.0 16.6 0.0 4.1 0.4 0.0 0.0 2.8 3.1 3.0 46.7 0.0 0.0 0.0 2.1 0.1 0.2 0.0 3.9 0.1 9.7 0.2 0.4 1.7 0.0 0.0 27.6 0.0 0.0 24.0 0.5 0.2 0.0 0.3 0.0 0.0 0.2 0.0 23.8 0.1 0.0 0.0 6.1 11.2 0.9 0.3 3.6 5.6 0.0 0.1 0.0 8.0 1.6 0.0 0.0 3.8 0.0 0.5 0.1 0.1 0.0 0.8 6.6 10.1 14.8 0.6 2.1 0.3 3.3 0.0 0.3 11.2 0.6 0.4 GALT ENSG00000213930 "Galactose-1-phosphate uridylyltransferase" P07902 9 34638133-34651035 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Galactose metabolism" "Nucleotidyltransferase, Transferase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 50.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004868, HPA005729" Enhanced Approved Cytosol NA NA 260000 "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA004868: AB_1079130, HPA005729: AB_1079131" "unprognostic (2.38e-1)" "unprognostic (8.92e-2)" "unprognostic (1.45e-3)" "unprognostic (1.54e-1)" "unprognostic (5.46e-2)" "unprognostic (1.22e-1)" "unprognostic (2.94e-1)" "unprognostic (2.13e-1)" "unprognostic (3.97e-2)" "unprognostic (1.13e-2)" "prognostic favorable (3.11e-5)" "unprognostic (9.68e-2)" "prognostic favorable (6.25e-6)" "unprognostic (7.90e-2)" "unprognostic (2.74e-1)" "unprognostic (3.56e-1)" "unprognostic (7.75e-2)" 6.7 14.0 5.3 6.7 5.9 8.1 6.3 5.5 6.5 6.9 4.6 8.5 18.3 6.9 5.3 5.3 7.8 6.8 10.4 5.2 6.3 10.0 50.0 6.6 12.0 5.5 5.7 8.2 7.5 13.0 6.1 9.2 5.3 6.4 6.7 6.3 12.3 7.5 10.2 15.2 16.5 4.0 4.5 9.7 8.1 2.4 6.1 7.8 8.2 7.6 7.7 5.3 6.1 4.7 5.5 7.5 6.8 2.4 9.0 9.2 7.8 4.2 12.1 4.3 5.1 9.5 4.8 6.1 4.2 5.2 1.6 2.9 1.3 11.8 0.8 9.7 4.8 2.5 14.7 9.8 8.7 1.4 2.9 12.6 7.4 2.7 3.6 9.3 10.6 8.3 2.3 6.4 7.3 5.1 5.4 10.3 2.3 6.7 1.3 8.4 5.9 3.3 12.5 7.8 1.6 5.7 5.0 9.8 5.4 5.0 9.2 8.2 1.6 1.7 3.4 3.4 0.0 3.9 2.4 1.3 4.1 4.4 10.8 16.5 23.7 11.7 15.4 21.5 21.3 24.8 25.2 21.1 21.5 13.2 15.3 14.8 4.6 29.0 20.4 18.2 30.0 17.6 5.3 5.9 5.5 6.5 5.2 6.3 5.5 5.7 5.3 4.5 6.1 4.7 12.6 6.4 21.2 10.7 19.0 21.7 13.4 19.3 19.4 44.0 10.5 12.1 25.7 14.3 15.4 16.5 47.9 72.5 13.9 17.3 29.4 18.3 7.6 7.8 11.8 14.6 16.3 13.7 9.1 7.3 36.3 18.3 9.2 8.0 20.3 24.7 23.6 69.9 24.1 47.1 12.5 17.0 26.4 15.5 8.7 36.8 18.3 12.4 21.4 5.6 15.9 18.7 34.0 6.0 3.7 6.9 37.5 13.9 10.7 4.7 67.1 46.3 11.1 38.5 6.6 11.2 12.2 4.8 6.6 8.6 20.2 59.1 25.5 27.4 20.4 9.2 GC "DBP, hDBP, VDBP" ENSG00000145321 "GC vitamin D binding protein" P02774 4 71741696-71804041 "Metabolic proteins, Plasma proteins, Predicted secreted proteins" Transport Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "liver: 8260.1" "Group enriched" "Detected in some" 27 "Cholangiocytes: 1552.8;Hepatocytes: 3017.1" "Cancer enriched" "Detected in many" 18 "liver cancer: 1016.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HL-60: 2.0;RH-30: 3.0;SiHa: 1.8;U-698: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001526, CAB008596, HPA019855" Supported "Secreted to blood" NA NA 143000000000 73000000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 15: Hepatocytes - Hemostasis" "CAB008596: AB_1622398, HPA001526: AB_1078959, HPA019855: AB_1849545" "prognostic favorable (8.08e-4)" "unprognostic (1.06e-3)" "prognostic unfavorable (5.81e-5)" "unprognostic (1.55e-1)" "unprognostic (2.15e-1)" 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 60.3 0.0 0.6 0.1 0.0 495.5 0.1 0.0 0.0 46.1 8260.1 0.0 0.2 0.1 0.1 0.0 44.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 8.0 0.0 0.0 1.8 51.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.4 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.3 0.0 1.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 7.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 1552.8 0.0 0.0 0.0 0.0 0.0 0.0 5.9 39.5 0.5 0.1 0.0 2.0 0.0 37.5 0.1 16.2 0.2 0.0 0.0 0.0 0.0 0.0 58.5 3017.1 0.1 0.0 0.1 0.7 0.0 83.0 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.0 35.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.4 0.0 0.0 0.0 GCDH ACAD5 ENSG00000105607 "Glutaryl-CoA dehydrogenase" Q92947 19 12891160-12914207 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 89.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 115.5;Proximal tubular cells: 147.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043252, HPA048492" Enhanced Supported Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA043252: AB_2678390, HPA048492: AB_2680418" "unprognostic (2.46e-1)" "unprognostic (1.64e-3)" "unprognostic (6.79e-3)" "unprognostic (8.07e-3)" "unprognostic (8.20e-3)" "unprognostic (3.14e-2)" "prognostic favorable (7.28e-5)" "prognostic favorable (3.35e-4)" "unprognostic (1.62e-1)" "unprognostic (3.03e-2)" "unprognostic (7.50e-3)" "unprognostic (7.46e-2)" "prognostic favorable (6.79e-8)" "unprognostic (7.09e-3)" "unprognostic (3.42e-1)" "unprognostic (5.32e-2)" "unprognostic (1.59e-1)" 16.8 17.8 20.2 11.2 22.4 13.0 15.6 22.1 23.3 10.2 21.8 13.2 11.8 12.6 8.6 14.0 15.2 8.4 29.3 19.2 19.4 24.5 89.1 9.3 16.8 20.7 20.9 16.8 15.5 11.5 10.6 5.4 21.0 13.6 8.5 5.5 20.0 11.5 30.5 10.1 13.0 8.2 19.9 12.8 18.6 4.5 20.9 17.8 11.9 27.1 11.9 14.9 9.9 22.7 22.9 14.1 15.0 27.5 21.4 9.8 13.8 17.2 11.1 21.6 15.7 26.9 10.8 33.0 31.9 10.5 10.8 15.6 20.8 16.4 10.6 28.6 22.8 21.0 24.6 33.1 24.8 43.7 18.8 13.8 19.9 15.3 16.1 8.8 18.1 44.4 51.8 11.4 10.7 28.9 51.7 41.7 16.7 22.0 36.1 48.2 15.3 68.9 12.6 12.1 32.3 18.9 22.8 22.6 16.7 9.6 17.8 29.3 13.3 18.0 12.9 29.9 18.2 59.5 32.2 34.6 11.0 50.7 15.4 13.9 13.9 8.5 18.8 12.1 18.8 18.1 23.2 21.0 24.0 19.5 30.9 23.8 3.1 38.8 9.8 14.7 21.4 20.0 20.2 22.4 22.1 23.3 19.2 19.4 20.7 20.9 21.0 19.9 20.9 22.7 6.0 3.2 5.3 25.5 21.2 7.9 14.5 13.3 11.4 14.2 17.3 10.8 10.0 22.8 8.6 11.0 25.0 16.2 17.2 11.6 52.8 14.0 2.6 7.7 10.0 7.3 15.6 60.4 7.1 11.2 21.5 10.2 12.8 10.9 7.0 19.5 13.6 115.5 21.5 8.4 7.4 13.8 16.2 14.4 5.0 1.8 13.1 9.9 17.8 5.6 20.7 18.6 18.6 14.6 15.1 10.2 9.7 12.8 25.4 11.3 17.4 147.8 7.2 12.3 0.0 13.7 9.8 8.3 7.4 13.4 5.3 16.3 20.9 33.0 20.6 12.1 GCK "HK4, MODY2" ENSG00000106633 Glucokinase P35557 7 44143213-44198170 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 12.6;choroid plexus: 7.4;heart muscle: 8.8;liver: 21.5;pituitary gland: 23.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 5.0;Cardiomyocytes: 4.9;Fibroblasts: 5.2;Horizontal cells: 5.0;Smooth muscle cells: 3.7" "Cancer enhanced" "Detected in some" "liver cancer: 4.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.3;naive CD4 T-cell: 2.0" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 6.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007034, HPA007093" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "HPA007034: AB_1079050, HPA007093: AB_1079051" "unprognostic (3.09e-1)" "unprognostic (2.99e-2)" "unprognostic (3.32e-2)" "unprognostic (6.64e-7)" "unprognostic (8.00e-2)" "unprognostic (2.75e-1)" "unprognostic (1.07e-2)" "unprognostic (2.68e-1)" "unprognostic (1.24e-1)" "unprognostic (5.48e-2)" "unprognostic (8.11e-3)" "unprognostic (3.08e-1)" "unprognostic (3.79e-3)" "unprognostic (2.01e-2)" "unprognostic (3.24e-1)" "unprognostic (4.36e-2)" "unprognostic (1.53e-1)" 0.8 0.3 8.9 0.3 8.3 0.2 0.7 8.1 9.5 2.8 7.4 0.5 0.1 1.2 0.8 0.4 1.2 0.5 8.8 8.2 11.0 1.2 21.5 0.4 0.2 9.0 9.9 1.4 1.8 0.1 23.9 1.6 9.1 1.2 0.2 1.0 0.3 0.7 0.2 0.7 0.5 0.3 8.3 0.6 0.6 0.4 12.6 0.1 0.5 0.1 0.2 1.1 2.0 7.9 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.5 0.0 0.7 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 1.2 1.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.6 0.0 0.2 0.2 0.1 0.0 0.1 0.0 0.3 2.3 0.7 0.1 0.1 0.3 2.0 0.4 0.8 0.1 0.0 0.1 0.0 0.3 8.9 8.3 8.1 9.5 8.2 11.0 9.0 9.9 9.1 8.3 12.6 7.9 0.3 0.0 0.0 0.7 0.3 1.1 0.7 0.0 1.2 5.0 0.1 0.8 4.9 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.0 1.3 0.5 2.4 0.0 1.8 0.0 0.2 5.2 0.0 0.0 0.0 2.4 0.0 0.4 0.7 5.0 2.4 0.0 0.0 0.0 0.7 0.3 0.9 0.1 0.0 1.0 0.0 2.8 0.0 0.5 1.0 0.1 0.1 2.2 0.2 1.7 0.0 0.1 0.0 0.8 0.0 0.6 3.7 0.5 1.1 0.0 0.1 0.8 0.3 0.5 0.0 0.7 GCLC "GCS, GLCL, GLCLC" ENSG00000001084 "Glutamate-cysteine ligase catalytic subunit" P48506 6 53497341-53616970 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glutathione biosynthesis" Ligase "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 152.1" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 220.7;Urothelial cells: 144.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 4.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "A549: 205.4;Hep G2: 178.2;OE19: 287.5;RT4: 189.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009569, HPA036359, HPA036360" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA 5800000 "Cluster 15: NK-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Nucleoli, Cytosol" "CAB009569: AB_675582, HPA036359: AB_10672243, HPA036360: AB_10669789" "unprognostic (8.41e-2)" "unprognostic (1.27e-2)" "unprognostic (5.65e-2)" "unprognostic (2.42e-1)" "unprognostic (1.58e-1)" "unprognostic (2.76e-1)" "unprognostic (2.60e-1)" "unprognostic (7.50e-2)" "unprognostic (9.94e-3)" "unprognostic (4.67e-3)" "unprognostic (1.30e-1)" "unprognostic (5.23e-2)" "prognostic favorable (3.83e-6)" "unprognostic (3.78e-2)" "unprognostic (8.91e-2)" "prognostic unfavorable (8.24e-4)" "unprognostic (2.30e-2)" 26.7 18.3 18.5 16.6 24.9 37.8 27.2 18.1 23.3 9.5 14.1 22.8 41.9 19.2 10.8 37.0 62.9 32.1 16.4 16.8 18.9 34.1 152.1 10.9 26.2 18.4 19.7 8.5 15.9 18.3 4.8 9.1 20.4 26.9 26.0 14.4 13.1 15.8 11.4 18.8 32.2 16.0 18.2 39.1 32.9 11.3 22.5 13.7 30.0 14.5 24.0 63.7 14.5 36.0 31.3 205.4 16.5 39.1 19.4 8.6 22.1 15.5 24.9 11.4 13.3 30.5 70.7 59.1 28.7 14.1 86.9 43.3 50.7 112.5 15.3 46.9 31.4 39.6 38.3 178.2 22.1 52.8 23.5 13.5 46.6 12.8 56.8 15.0 17.7 50.9 22.4 18.2 5.6 32.9 45.5 20.9 30.6 287.5 19.2 14.9 10.2 52.1 37.0 189.8 47.5 23.3 25.9 40.9 27.8 23.8 28.2 24.6 24.6 10.2 35.5 26.0 23.4 24.1 39.9 34.0 25.6 37.0 17.5 1.2 0.5 0.3 0.5 0.9 0.4 0.8 0.5 1.1 2.3 0.5 0.3 0.6 0.2 4.2 1.0 1.6 0.9 0.3 18.5 24.9 18.1 23.3 16.8 18.9 18.4 19.7 20.4 18.2 22.5 36.0 17.1 0.0 2.4 36.9 12.7 34.8 61.6 56.6 47.3 14.4 23.7 13.6 20.9 38.6 47.4 0.0 25.0 6.4 22.9 22.1 11.7 14.6 2.2 34.8 14.9 14.1 220.7 113.2 22.4 12.8 8.6 13.6 43.8 69.8 2.5 50.9 10.4 118.5 22.7 8.4 30.4 19.4 40.7 87.2 10.9 1.5 6.5 32.1 8.8 24.4 10.6 12.5 17.5 30.2 84.1 15.9 13.2 9.4 10.4 88.3 18.2 27.1 66.5 5.0 13.1 14.0 13.5 3.1 9.2 72.6 24.9 7.8 14.9 26.6 14.8 144.8 GDF11 "BMP-11, BMP11" ENSG00000135414 "Growth differentiation factor 11" O95390 12 55743122-55757264 "Predicted secreted proteins" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 26.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 76.6;Cone photoreceptor cells: 77.2;Horizontal cells: 57.2;Rod photoreceptor cells: 53.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HMC-1: 127.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060985, HPA069609" Approved Approved Vesicles "Secreted to blood" No No 46400 340000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 3: HMC-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA060985: AB_2684403, HPA069609: AB_2686159" "unprognostic (5.21e-2)" "unprognostic (1.62e-1)" "unprognostic (3.20e-2)" "unprognostic (2.41e-2)" "unprognostic (2.78e-2)" "unprognostic (3.39e-1)" "unprognostic (2.13e-1)" "unprognostic (2.62e-2)" "unprognostic (8.96e-3)" "unprognostic (1.23e-2)" "prognostic favorable (1.08e-4)" "unprognostic (2.69e-1)" "unprognostic (1.62e-2)" "unprognostic (1.27e-1)" "unprognostic (3.13e-1)" "unprognostic (1.01e-3)" "unprognostic (9.48e-2)" 3.6 4.0 22.5 3.7 17.5 1.8 2.3 16.4 17.8 6.8 15.9 5.4 1.6 7.6 2.0 2.4 5.0 4.6 7.5 18.1 18.5 3.0 1.3 3.6 2.8 22.0 26.6 5.7 2.9 2.9 4.7 2.0 20.9 6.0 1.6 21.6 4.8 9.4 1.8 1.5 3.7 4.6 18.3 5.6 2.7 1.1 22.3 4.6 3.6 2.0 1.8 5.9 3.4 17.7 4.9 7.6 32.8 18.6 24.4 17.8 8.2 10.1 9.5 12.5 10.7 26.0 2.1 9.5 13.0 10.5 5.9 4.6 25.0 18.0 4.3 18.2 22.7 11.7 12.3 4.1 4.9 9.8 127.7 17.2 1.0 18.3 5.2 14.0 16.4 12.7 13.2 30.1 16.0 9.2 16.0 8.5 26.4 0.3 18.9 25.1 8.9 5.9 7.7 6.6 22.2 13.6 6.2 2.8 2.6 13.3 10.7 10.7 10.1 15.0 22.9 11.9 7.4 8.1 2.6 4.9 8.0 9.7 10.8 0.2 0.2 0.5 1.2 0.1 1.0 0.7 0.7 0.7 0.2 0.7 0.6 0.8 0.3 0.2 0.4 0.7 0.5 0.1 22.5 17.5 16.4 17.8 18.1 18.5 22.0 26.6 20.9 18.3 22.3 17.7 8.4 0.0 1.1 19.2 10.9 0.5 9.8 0.6 4.0 76.6 6.3 6.6 25.6 1.5 0.9 0.0 77.2 3.6 16.6 1.5 0.0 5.0 0.6 9.9 35.2 8.0 10.7 11.1 4.3 1.4 5.3 13.3 3.1 18.0 5.7 7.6 6.4 0.2 1.6 57.2 10.8 1.9 0.0 1.9 0.7 0.8 9.0 4.4 3.6 1.9 4.1 30.6 22.6 17.1 3.2 3.3 4.1 5.7 4.1 9.8 3.4 0.5 0.1 53.1 13.1 31.1 18.1 2.9 4.1 3.0 0.9 4.7 18.9 7.2 2.2 6.2 GDF2 "BMP-9, BMP9" ENSG00000263761 "Growth differentiation factor 2" Q9UK05 10 47322454-47327588 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Angiogenesis "Cytokine, Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 45 "liver: 18.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB023357 Uncertain "Secreted to blood" NA NA 2210000 740000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 43: Cardiomyocytes - Nuclear processes" "CAB023357: AB_2111086" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GDF6 "BMP13, KFS, KFS1, SGM1" ENSG00000156466 "Growth differentiation factor 6" Q6KF10 8 96142333-96160806 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Cytokine, Developmental protein, Growth factor" "Disease variant, Dwarfism, Leber congenital amaurosis, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 10.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.3;Distal tubular cells: 1.9;Excitatory neurons: 1.6;Fibroblasts: 3.1;Oligodendrocyte precursor cells: 7.1;Spermatogonia: 2.4" "Cancer enhanced" "Detected in some" "renal cancer: 2.8;thyroid cancer: 2.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTERT-RPE1: 20.4;LHCN-M2: 33.1;SuSa: 15.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "midbrain: 1.2" HPA045206 Uncertain Supported "Nucleoplasm,Nuclear membrane,Vesicles" "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Nuclear membrane" "HPA045206: AB_10962508" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.83e-2)" "unprognostic (9.66e-9)" "unprognostic (6.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-3)" "unprognostic (5.37e-2)" "unprognostic (8.13e-3)" "prognostic unfavorable (2.17e-4)" "unprognostic (5.88e-4)" "unprognostic (1.88e-2)" "unprognostic (2.68e-2)" "unprognostic (1.71e-1)" 1.3 0.1 0.3 0.9 0.3 0.0 0.4 0.4 0.8 0.2 0.0 0.7 0.3 1.4 0.4 0.4 0.5 2.4 2.8 0.3 0.4 0.2 0.4 0.2 0.1 0.8 0.4 0.1 0.7 0.1 0.1 10.9 1.0 0.3 0.3 0.0 0.0 1.4 0.0 0.0 0.9 1.1 0.4 0.0 0.6 0.6 0.8 0.1 0.6 0.0 0.0 0.8 0.9 0.4 0.0 0.0 0.2 0.0 1.1 0.6 3.9 2.6 0.0 2.3 2.0 0.0 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.0 3.2 0.0 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.1 0.0 3.0 0.0 20.4 0.2 0.0 0.0 0.0 33.1 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.8 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.4 0.8 0.3 0.4 0.8 0.4 1.0 0.4 0.8 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.8 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 1.0 2.4 0.0 0.0 0.3 0.1 0.0 0.0 0.1 GDPD4 GDE6 ENSG00000178795 "Glycerophosphodiester phosphodiesterase domain containing 4" Q6W3E5 11 77216558-77301687 "Predicted membrane proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "retina: 1.5;testis: 3.7" "Group enriched" "Detected in some" 9 "Early spermatids: 10.9;Late spermatids: 18.0;Spermatocytes: 17.7;Spermatogonia: 5.3;Theca cells: 5.6" "Cancer enriched" "Detected in single" 10 "testis cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 23 "olfactory bulb: 2.3" NA NA "Cluster 77: Retina - Visual perception" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "unprognostic (6.73e-6)" "unprognostic (3.30e-1)" "unprognostic (2.01e-2)" "unprognostic (1.68e-1)" "unprognostic (2.12e-1)" "unprognostic (3.55e-4)" "unprognostic (4.13e-2)" "unprognostic (5.41e-2)" "unprognostic (1.53e-1)" "unprognostic (2.63e-2)" "unprognostic (3.10e-2)" "unprognostic (4.75e-2)" "unprognostic (1.05e-4)" "unprognostic (1.68e-2)" "unprognostic (1.19e-1)" "unprognostic (1.29e-2)" "unprognostic (1.64e-2)" 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.5 0.0 0.0 0.0 0.0 18.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 17.7 5.3 0.0 0.0 0.3 0.0 5.6 0.0 0.0 GGT5 "GGT-REL, GGTLA1" ENSG00000099998 "Gamma-glutamyltransferase 5" P36269 22 24219654-24245108 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glutathione biosynthesis, Leukotriene biosynthesis" "Acyltransferase, Hydrolase, Protease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endothelial cells: 42.8;Fibroblasts: 58.3;Leydig cells: 36.4;Sertoli cells: 184.1;Smooth muscle cells: 85.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.3;eosinophil: 4.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 4.5" "Cell line enhanced" "Detected in many" "ASC diff: 164.9;ASC TERT1: 124.4;HHSteC: 234.7;HSkMC: 271.7;TIME: 110.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008121, CAB032489" Uncertain Approved "Nucleoli fibrillar center" "Intracellular and membrane" NA NA 22000000 "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoli fibrillar center" "CAB032489: AB_2111010, HPA008121: AB_1078965" "unprognostic (8.14e-2)" "unprognostic (2.53e-1)" "unprognostic (5.66e-2)" "unprognostic (9.94e-2)" "unprognostic (8.13e-2)" "unprognostic (8.21e-2)" "unprognostic (2.33e-2)" "unprognostic (2.90e-1)" "unprognostic (1.81e-2)" "unprognostic (1.07e-1)" "unprognostic (8.37e-2)" "unprognostic (7.94e-2)" "prognostic unfavorable (6.36e-5)" "prognostic unfavorable (4.06e-4)" "prognostic unfavorable (6.97e-4)" "unprognostic (1.79e-1)" "unprognostic (8.33e-2)" 137.6 60.5 39.0 18.6 39.3 1.4 90.6 37.6 41.7 73.2 32.8 27.8 19.4 54.4 12.9 19.6 70.6 37.2 93.4 35.0 45.1 78.2 55.2 37.7 48.0 52.2 46.3 26.6 25.8 13.2 41.1 11.9 46.9 49.3 12.0 2.1 37.1 20.9 23.1 40.1 40.8 32.2 41.9 36.1 40.0 9.6 45.3 10.4 110.2 16.6 18.3 45.1 64.2 38.2 0.0 1.8 0.6 0.0 164.9 124.4 1.1 2.9 0.2 0.1 0.0 0.1 0.1 0.2 3.4 0.2 0.3 0.3 0.1 0.1 0.0 2.2 0.9 6.7 1.0 24.1 234.7 3.0 6.4 271.7 0.1 3.4 3.2 0.4 45.8 0.7 0.4 1.2 44.1 0.4 0.0 22.4 3.6 1.1 0.0 0.1 4.0 1.0 6.1 0.0 0.4 5.9 0.1 7.3 0.1 22.7 1.0 1.7 110.8 0.1 2.3 0.1 0.0 0.3 1.5 0.2 3.9 5.7 0.2 2.3 0.5 4.5 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.2 39.0 39.3 37.6 41.7 35.0 45.1 52.2 46.3 46.9 41.9 45.3 38.2 27.2 3.2 16.0 1.0 0.3 7.0 3.3 3.2 0.0 0.0 7.2 4.2 4.4 0.0 17.9 0.0 0.0 0.2 0.4 0.0 0.0 0.6 0.8 0.3 8.3 42.8 0.0 2.7 0.1 0.2 0.2 58.3 1.1 0.4 1.3 0.0 33.5 0.1 2.1 0.0 0.1 0.0 0.0 1.0 12.5 3.3 36.4 1.8 3.6 22.5 3.3 0.3 0.0 0.5 0.0 0.4 0.0 23.7 0.3 2.2 0.0 0.1 2.2 1.0 184.1 33.9 85.6 0.6 0.4 0.3 4.4 0.3 1.1 2.1 0.0 1.4 GHR GHBP ENSG00000112964 "Growth hormone receptor" P10912 5 42423439-42721878 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 84.7;liver: 213.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 53.3;Hepatocytes: 141.3;Inhibitory neurons: 115.7;Oligodendrocyte precursor cells: 181.0" "Group enriched" "Detected in many" 4 "breast cancer: 2.8;liver cancer: 7.6;prostate cancer: 8.1;renal cancer: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HSkMC: 21.2;T-47d: 56.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045339, HPA057705" Enhanced Supported "Plasma membrane,Cytosol,Cytoplasmic bodies" "Secreted to blood" NA NA 2200000 24000000 "Cluster 85: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol, Cytoplasmic bodies" "HPA045339: AB_2679294, HPA057705: AB_2683507" "unprognostic (2.18e-2)" "unprognostic (5.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.96e-2)" "unprognostic (3.12e-1)" "unprognostic (1.57e-1)" "prognostic favorable (2.73e-6)" "unprognostic (1.06e-1)" "unprognostic (3.92e-2)" "unprognostic (3.73e-2)" "unprognostic (6.15e-3)" "unprognostic (2.67e-2)" "unprognostic (1.67e-3)" "unprognostic (4.29e-4)" "unprognostic (7.82e-2)" "unprognostic (7.33e-4)" "unprognostic (8.35e-6)" 84.7 5.6 1.8 1.7 2.1 0.2 30.1 1.7 1.7 5.2 2.3 5.8 1.1 4.5 4.6 3.9 5.4 5.2 8.9 1.8 5.6 11.8 213.3 4.0 1.3 1.0 2.0 7.5 2.1 5.5 1.2 4.8 1.4 11.1 5.7 0.4 3.7 4.7 45.7 5.6 4.3 4.0 1.1 4.0 6.1 1.7 3.4 2.3 4.6 11.6 0.9 5.0 5.8 1.4 0.0 0.0 0.6 5.0 3.3 0.7 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.3 4.3 0.0 0.0 2.6 0.0 0.1 0.0 0.6 0.0 0.0 21.2 7.0 0.0 1.0 0.1 0.1 0.0 0.0 0.0 1.8 0.2 0.0 0.0 0.3 0.0 0.7 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.3 0.1 3.5 0.6 56.0 0.1 3.0 4.8 2.1 2.6 0.5 0.5 0.0 0.0 0.5 0.0 2.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 2.1 1.7 1.7 1.8 5.6 1.0 2.0 1.4 1.1 3.4 1.4 17.2 0.0 0.5 14.7 0.4 4.7 4.5 17.8 10.2 0.6 9.7 16.0 18.6 1.5 1.9 1.8 0.0 17.4 0.5 2.8 1.9 0.0 5.1 0.5 9.4 4.8 3.0 5.3 53.3 0.2 2.2 23.8 0.5 0.3 0.0 1.1 6.1 141.3 1.9 0.0 115.7 1.9 0.0 3.0 1.8 2.8 18.6 0.7 1.8 36.5 0.0 0.7 0.0 181.0 3.6 0.2 1.7 12.0 0.0 5.2 0.0 9.6 0.6 0.4 13.1 18.7 15.1 0.7 0.3 2.9 3.7 40.2 0.5 49.4 2.2 0.9 GLUD1 "GDH, GLUD" ENSG00000148672 "Glutamate dehydrogenase 1" P00367 10 87050202-87094843 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 816.4" "Cell type enhanced" "Detected in all" "Astrocytes: 294.1;Hepatocytes: 402.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 555.0" "Low region specificity" "Detected in all" "HPA042492, HPA044839, HPA061369" Approved Supported Mitochondria "Intracellular and membrane" NA NA 23000000 "Cluster 26: Non-specific - Mitochondria" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA042492: AB_2678024, HPA044839: AB_2679107, HPA061369: AB_2684494" "unprognostic (1.48e-1)" "unprognostic (1.26e-2)" "unprognostic (3.55e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.81e-4)" "unprognostic (1.31e-1)" "unprognostic (1.91e-2)" "unprognostic (5.50e-2)" "unprognostic (2.06e-1)" "unprognostic (4.57e-3)" "prognostic unfavorable (1.76e-5)" "unprognostic (1.13e-1)" "prognostic favorable (1.44e-6)" "unprognostic (2.29e-1)" "unprognostic (4.23e-2)" "unprognostic (7.19e-2)" "unprognostic (4.27e-2)" 70.1 93.0 217.2 44.8 219.0 29.2 96.4 180.4 216.8 50.2 135.8 63.4 80.9 48.1 30.0 77.0 47.4 53.3 75.6 193.3 223.2 249.2 816.4 57.7 42.9 220.9 222.9 71.6 66.2 39.0 37.1 58.8 202.3 110.5 61.5 90.2 55.6 53.2 51.1 84.2 88.6 53.3 223.2 46.4 57.0 22.3 254.6 44.8 68.1 64.4 59.2 68.1 55.6 202.3 127.1 100.3 77.1 131.5 143.0 174.5 84.0 97.7 167.8 92.4 100.5 233.0 120.6 141.5 77.8 143.4 53.0 194.7 101.4 98.5 98.0 102.7 79.8 69.0 55.9 555.0 318.1 163.2 95.5 121.3 181.5 103.2 304.9 140.3 112.0 109.3 70.7 124.0 101.0 92.1 148.1 145.7 88.2 136.9 79.8 110.4 98.3 93.1 267.4 101.8 39.7 73.9 87.8 68.8 126.1 73.9 94.3 112.8 112.4 47.8 42.5 98.2 101.0 73.6 81.4 167.5 115.3 182.8 29.3 9.1 14.2 9.7 8.3 11.1 10.3 9.8 11.2 10.1 15.9 11.3 9.9 8.0 1.2 13.6 16.0 5.9 12.6 6.5 217.2 219.0 180.4 216.8 193.3 223.2 220.9 222.9 202.3 223.2 254.6 202.3 49.3 22.4 23.9 294.1 56.6 106.0 57.5 32.2 105.3 22.5 83.3 38.2 60.2 57.2 47.3 60.7 37.5 95.7 45.6 56.1 156.5 32.5 14.2 37.3 44.0 54.1 39.4 52.6 35.8 33.8 63.8 89.0 86.2 59.7 43.2 33.6 50.7 402.3 69.1 15.2 38.0 49.5 36.7 74.1 184.5 26.0 88.0 81.4 104.9 42.2 50.6 140.0 39.1 48.7 42.9 50.2 38.3 90.7 75.7 103.4 124.2 175.5 21.6 68.9 65.7 41.3 55.9 11.4 8.6 189.5 122.3 47.6 84.6 70.9 49.6 107.3 GNE "IBM2, Uae1" ENSG00000159921 "Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase" Q9Y223 9 36214441-36277042 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Allosteric enzyme, Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "intestine: 48.4;liver: 90.5;salivary gland: 55.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 59.3;Hepatocytes: 119.3;Intestinal goblet cells: 88.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 107.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007045, HPA027258" Approved Supported Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "HPA007045: AB_1079003, HPA027258: AB_1849873" "unprognostic (7.54e-2)" "unprognostic (1.61e-2)" "unprognostic (1.07e-3)" "unprognostic (7.28e-2)" "unprognostic (7.00e-2)" "unprognostic (1.85e-2)" "unprognostic (2.78e-3)" "unprognostic (5.39e-2)" "unprognostic (1.73e-1)" "unprognostic (1.70e-2)" "unprognostic (2.88e-3)" "unprognostic (4.20e-2)" "prognostic favorable (9.28e-11)" "unprognostic (2.90e-1)" "unprognostic (8.28e-2)" "unprognostic (2.95e-1)" "unprognostic (1.72e-2)" 11.9 9.0 5.5 8.7 7.4 15.5 15.8 8.9 6.5 11.3 7.9 34.0 4.3 10.3 3.5 11.6 9.1 7.4 7.7 5.5 7.3 10.0 90.5 6.8 7.3 7.7 7.3 14.8 10.2 6.1 4.8 14.2 8.9 15.3 48.4 8.0 55.3 7.2 7.9 3.8 7.6 11.7 6.6 6.2 4.6 4.8 7.1 6.2 6.9 15.3 9.5 14.2 7.5 10.5 9.9 44.4 20.1 17.1 22.5 22.4 29.9 13.5 17.9 19.5 25.1 10.5 32.6 13.5 14.2 24.2 50.5 3.9 15.3 4.6 21.8 25.1 1.4 11.0 26.0 15.2 15.4 0.2 31.2 14.4 4.6 32.0 30.6 14.3 8.4 20.7 14.4 27.3 19.3 1.8 19.1 6.3 11.8 6.7 23.7 15.5 16.3 3.8 107.7 19.4 16.7 15.2 13.7 5.3 12.6 7.1 4.8 12.0 12.2 12.7 12.9 15.5 12.2 11.7 26.0 7.0 17.0 9.8 18.2 0.2 0.5 0.2 0.7 0.6 0.5 0.6 0.9 0.8 0.4 0.9 1.0 1.2 0.3 0.7 0.8 0.6 0.4 0.6 5.5 7.4 8.9 6.5 5.5 7.3 7.7 7.3 8.9 6.6 7.1 10.5 9.7 9.6 10.0 9.4 7.1 1.9 3.1 6.7 1.8 8.4 8.2 7.5 6.7 10.0 16.9 9.2 6.2 8.6 4.3 59.3 1.9 10.4 3.4 7.2 12.1 6.3 11.5 7.8 12.8 6.0 9.5 8.3 2.6 10.6 10.1 9.1 7.1 119.3 2.9 11.8 15.6 88.1 16.2 7.8 4.4 2.4 10.8 5.4 1.8 5.6 6.1 1.9 2.1 32.2 28.2 5.3 20.3 6.4 7.9 6.9 2.9 2.2 18.8 6.9 13.1 10.0 6.3 1.8 2.7 1.2 1.6 19.8 5.7 2.3 26.8 13.4 GNG7 FLJ00058 ENSG00000176533 "G protein subunit gamma 7" O60262 19 2511219-2702694 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 14 "brain: 360.9" "Cell type enhanced" "Detected in many" "B-cells: 145.4;Distal tubular cells: 123.3;Horizontal cells: 169.9;Oligodendrocyte precursor cells: 102.5;Oligodendrocytes: 206.1;Plasma cells: 169.7" "Cancer enhanced" "Detected in all" "glioma: 21.9;melanoma: 20.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 57.2;naive B-cell: 50.1;plasmacytoid DC: 48.0" "Group enriched" "Detected in many" 4 "B-cells: 57.2;dendritic cells: 48.0" "Cell line enhanced" "Detected in many" "Daudi: 22.3;REH: 66.5;SK-MEL-30: 31.2;U-266/70: 61.0;U-266/84: 30.0" "Region enriched" "Detected in all" 6 "basal ganglia: 1277.2" HPA057790 Supported Supported NA NA 72000 "Cluster 43: B-cells - Humoral immune response" "Cluster 65: Brain - Ion transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA057790: AB_2683527" "unprognostic (3.97e-3)" "unprognostic (1.16e-4)" "unprognostic (4.92e-2)" "unprognostic (2.72e-1)" "unprognostic (2.79e-1)" "unprognostic (8.42e-4)" "prognostic favorable (3.05e-4)" "prognostic favorable (1.35e-5)" "unprognostic (1.27e-2)" "unprognostic (4.95e-2)" "prognostic favorable (3.71e-4)" "unprognostic (1.27e-1)" "prognostic favorable (0.00e+0)" "unprognostic (6.96e-2)" "unprognostic (1.46e-1)" "unprognostic (6.36e-2)" "unprognostic (4.96e-2)" 3.5 5.7 70.8 5.3 360.9 6.6 4.4 83.9 127.9 5.5 14.0 6.7 5.2 7.2 5.1 12.0 8.2 3.5 26.4 70.1 66.0 10.5 4.2 4.0 9.9 97.2 87.9 12.2 8.0 6.2 17.4 1.4 76.8 9.5 3.1 15.1 26.0 5.7 3.4 2.6 14.2 3.5 76.0 19.4 6.8 8.9 154.1 2.7 5.8 8.1 9.4 7.9 3.3 81.4 0.2 0.0 3.2 7.1 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.7 22.3 1.0 0.3 0.3 0.2 3.5 0.0 0.1 0.0 3.1 0.6 0.1 2.7 1.6 0.0 12.9 0.4 0.5 0.0 0.2 0.2 0.0 2.7 0.3 14.2 0.0 2.2 0.6 1.4 2.6 0.4 1.4 66.5 0.0 6.2 0.3 0.0 0.1 9.2 0.1 0.1 31.2 2.1 0.4 5.6 0.1 0.1 3.0 0.2 0.2 61.0 30.0 4.7 0.2 7.0 16.5 3.5 1.5 8.0 0.4 0.5 1.1 57.2 0.5 0.4 6.0 50.1 1.2 0.7 11.8 0.2 0.1 48.0 0.0 3.0 70.8 360.9 83.9 127.9 70.1 66.0 97.2 87.9 76.8 76.0 154.1 81.4 14.5 6.4 4.2 40.8 145.4 2.5 13.0 0.3 5.2 10.5 22.9 30.1 55.1 15.7 3.3 9.2 8.4 0.6 56.1 0.9 123.3 17.0 5.4 2.1 2.3 11.7 6.1 8.6 26.5 4.8 1.1 6.6 5.6 3.5 12.7 8.6 19.2 11.4 63.2 169.9 38.8 2.0 0.0 8.5 15.0 11.4 2.5 12.3 51.6 45.9 11.2 84.7 3.1 102.5 206.1 2.7 1.8 2.6 169.7 7.5 0.7 22.6 2.9 11.1 6.6 7.1 5.4 2.7 2.6 1.5 2.0 3.4 6.9 2.1 2.2 7.2 GNLY "D2S69E, LAG-2, LAG2, NKG5, TLA519" ENSG00000115523 Granulysin P22749 2 85685175-85698852 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 288.7;endometrium 1: 71.9;lymphoid tissue: 86.3" "Group enriched" "Detected in many" 5 "dendritic cells: 5070.6;NK-cells: 8318.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "NK-cell: 17623.2" "Group enriched" "Detected in all" 63 "NK-cells: 17623.2;T-cells: 7874.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB025186, HPA058021" Enhanced "Secreted to blood" NA NA 2920000 17000 "Cluster 48: NK-cells - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB025186: , HPA058021: AB_2683581" "unprognostic (5.80e-2)" "unprognostic (5.64e-3)" "unprognostic (6.68e-2)" "prognostic favorable (3.48e-5)" "unprognostic (4.34e-2)" "unprognostic (9.22e-2)" "unprognostic (2.60e-1)" "unprognostic (2.79e-2)" "prognostic favorable (6.60e-5)" "unprognostic (2.61e-2)" "unprognostic (1.88e-1)" "unprognostic (1.82e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (8.46e-2)" "unprognostic (3.37e-1)" "unprognostic (1.86e-1)" "prognostic favorable (8.07e-4)" 6.9 2.7 8.1 11.6 7.8 288.7 5.2 8.1 18.7 4.3 7.1 5.7 4.0 71.9 3.9 2.6 6.1 6.5 4.3 7.8 9.8 2.9 10.4 36.8 21.9 12.7 11.6 1.5 1.2 0.8 1.8 17.0 10.6 2.0 6.1 0.5 2.0 5.3 9.2 1.5 10.3 4.3 8.8 86.3 5.0 0.9 9.8 3.5 3.6 3.5 17.6 6.4 2.5 9.8 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.4 0.1 0.0 177.1 26.2 17.7 7874.6 26.3 2145.8 34.2 837.4 3344.7 22.4 23.0 231.3 2928.7 202.5 17623.2 32.3 58.2 40.3 8118.6 8.1 7.8 8.1 18.7 7.8 9.8 12.7 11.6 10.6 8.8 9.8 9.8 26.8 12.8 78.9 0.0 23.3 7.0 0.2 0.0 0.0 0.1 7.2 3.7 3.0 10.0 6.2 0.0 2.1 2.3 5070.6 1.3 1.9 1.9 0.0 7.5 12.0 13.0 1.8 47.2 0.2 0.0 3.4 29.3 0.5 10.6 52.4 0.1 23.2 5.3 6.0 0.0 0.1 3.3 0.0 22.4 7.2 0.2 0.3 28.4 80.0 9.4 48.6 0.1 8318.3 0.0 0.1 0.0 1.2 0.0 247.4 0.1 2.4 9.5 3.6 0.2 0.0 7.0 5.4 0.2 0.6 0.6 7.7 1.1 1230.0 1.0 1.6 0.6 GOLGA6D ENSG00000140478 "Golgin A6 family member D" P0CG33 15 75282835-75295807 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 12.1" "Cell type enriched" "Detected in some" 4 "Early spermatids: 12.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044978, HPA050087, HPA072134" Supported Approved Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "Nucleoplasm, Centrosome" "HPA044978: AB_2679165, HPA050087: AB_2681010, HPA072134: " "unprognostic (7.95e-3)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 12.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 GPAM "GPAT1, KIAA1560, MGC26846" ENSG00000119927 "Glycerol-3-phosphate acyltransferase, mitochondrial" Q9HCL2 10 112149865-112215377 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 305.7;liver: 144.1" "Cell type enhanced" "Detected in many" "Astrocytes: 90.8;Hepatocytes: 184.5;Horizontal cells: 45.4" "Cancer enriched" "Detected in all" 5 "liver cancer: 20.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "ASC diff: 250.3;Hep G2: 71.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046339, HPA060090" Approved Approved Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA046339: AB_2679627, HPA060090: AB_2684202" "unprognostic (1.82e-1)" "unprognostic (6.28e-2)" "unprognostic (1.13e-1)" "unprognostic (1.30e-1)" "unprognostic (6.80e-2)" "unprognostic (8.75e-2)" "unprognostic (1.40e-2)" "unprognostic (2.16e-2)" "unprognostic (4.59e-1)" "unprognostic (4.80e-1)" "unprognostic (2.37e-2)" "unprognostic (5.44e-2)" "prognostic favorable (4.54e-6)" "unprognostic (2.84e-1)" "unprognostic (4.41e-2)" "unprognostic (2.52e-2)" "unprognostic (1.37e-1)" 305.7 33.9 14.9 4.8 17.1 3.4 67.7 12.2 14.0 3.0 6.9 6.4 4.0 4.2 75.1 2.9 3.1 6.0 12.3 12.4 13.0 4.4 144.1 4.1 4.6 12.9 16.0 5.3 5.0 4.3 2.1 3.0 12.1 3.9 4.7 5.1 17.2 5.3 8.3 3.2 6.1 4.9 11.5 2.9 4.9 5.6 15.7 3.6 12.4 8.8 4.3 4.8 2.6 10.5 9.9 7.4 9.7 12.9 250.3 9.1 12.7 9.2 10.5 6.6 5.1 17.3 5.7 6.9 5.0 6.5 6.1 12.3 15.5 7.9 12.3 5.0 8.4 6.4 7.9 71.8 7.7 11.2 3.4 43.8 13.1 11.7 23.6 49.7 5.8 9.7 8.5 6.1 7.7 5.6 9.6 8.8 8.1 5.6 10.1 9.7 25.4 5.1 4.3 6.8 4.1 12.1 12.8 6.1 14.5 8.9 6.3 4.0 4.4 7.5 4.6 9.4 14.8 6.1 7.3 14.3 8.8 9.8 5.8 0.0 0.3 0.1 0.7 0.4 0.9 0.5 0.5 0.5 0.4 1.1 0.5 0.9 0.0 0.3 0.3 0.6 0.6 0.3 14.9 17.1 12.2 14.0 12.4 13.0 12.9 16.0 12.1 11.5 15.7 10.5 9.1 9.6 27.1 90.8 5.2 0.4 0.8 1.6 4.6 5.3 8.1 8.4 18.9 20.0 4.3 5.5 10.4 5.2 4.3 1.7 1.9 2.7 0.5 5.1 10.0 5.0 1.2 12.2 8.2 3.3 2.9 5.1 3.6 4.2 2.5 12.7 6.4 184.5 3.1 45.4 9.4 3.0 0.0 9.3 1.0 0.9 5.3 1.9 1.8 10.3 1.4 6.1 3.1 10.1 10.1 3.4 2.7 12.0 6.4 1.1 3.7 3.3 4.7 9.1 6.6 4.3 6.6 4.0 3.2 5.4 0.1 1.9 3.3 8.6 5.0 0.6 GPLD1 ENSG00000112293 "Glycosylphosphatidylinositol specific phospholipase D1" P80108 6 24424565-24495205 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 46.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 68.8;Excitatory neurons: 62.4;Hepatocytes: 66.8;Inhibitory neurons: 78.3;Oligodendrocyte precursor cells: 33.2" "Cancer enriched" "Detected in some" 11 "liver cancer: 6.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 7.6;U-698: 8.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008625, HPA012500" Uncertain "Secreted to blood" NA NA 103000000000 3100000000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB008625: AB_1621070, HPA012500: AB_1849931" "unprognostic (6.80e-3)" "unprognostic (2.27e-1)" "unprognostic (1.59e-1)" "unprognostic (4.81e-5)" "unprognostic (3.65e-1)" "unprognostic (1.02e-1)" "prognostic favorable (1.12e-4)" "unprognostic (6.37e-4)" "unprognostic (7.93e-2)" "unprognostic (2.86e-2)" "unprognostic (6.07e-4)" "unprognostic (2.68e-1)" "unprognostic (5.28e-4)" "unprognostic (2.20e-1)" "unprognostic (9.98e-2)" "unprognostic (3.73e-2)" "unprognostic (1.22e-1)" 4.2 0.9 2.0 0.6 1.7 0.9 1.3 7.6 4.7 1.1 0.1 1.0 0.5 1.6 1.7 1.1 0.9 0.6 0.5 1.3 2.4 0.6 46.1 0.9 0.9 1.8 1.9 1.2 0.6 2.5 1.7 0.2 1.9 1.8 0.6 6.2 0.4 4.8 1.7 8.6 0.4 1.4 0.6 0.6 0.7 1.4 1.4 5.1 2.4 0.6 1.3 1.1 1.5 2.1 0.5 0.7 0.8 1.2 0.0 0.0 2.0 0.1 0.2 0.2 0.1 3.5 0.1 7.6 0.8 0.1 0.2 0.1 1.2 0.2 0.1 0.9 2.1 1.1 0.9 3.2 0.0 1.4 0.2 0.0 0.1 0.0 0.0 0.8 0.0 1.8 0.5 0.3 0.1 0.5 0.7 0.5 2.9 0.5 0.3 1.4 0.2 0.1 0.4 3.4 2.0 2.3 0.9 0.1 0.4 0.6 0.4 0.3 0.1 0.7 0.9 0.1 1.0 2.4 3.4 8.1 0.1 0.3 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.1 0.1 0.0 0.2 0.1 0.0 2.0 1.7 7.6 4.7 1.3 2.4 1.8 1.9 1.9 0.6 1.4 2.1 0.4 0.0 3.7 24.8 1.1 0.0 0.7 2.8 0.6 19.6 0.7 0.4 11.6 0.0 1.7 1.8 68.8 0.3 1.6 0.1 0.0 0.4 3.5 0.5 0.6 1.2 1.8 7.4 62.4 0.4 0.3 1.3 0.0 0.3 0.0 2.1 1.4 66.8 0.1 15.2 78.3 0.3 0.0 1.3 0.0 3.4 3.1 0.1 0.0 9.4 0.1 4.0 3.1 33.2 3.1 0.1 0.1 3.4 3.1 0.3 0.1 0.5 1.1 10.9 0.0 3.6 1.4 0.5 5.8 0.3 0.6 0.0 0.5 0.9 0.5 2.6 GRHL2 "BOM, DFNA28, FLJ13782, TFCP2L3" ENSG00000083307 "Grainyhead like transcription factor 2" Q6ISB3 8 101492439-101669726 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Corneal dystrophy, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 28.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 32.1;Respiratory ciliated cells: 28.8;Squamous epithelial cells: 27.1;Suprabasal keratinocytes: 26.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 39.3;CACO-2: 28.0;HaCaT: 46.3;hTCEpi: 35.5;MCF7: 32.7;OE19: 37.9;RT4: 68.9;T-47d: 79.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004820, HPA062839" Uncertain Supported Nucleoplasm NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA004820: AB_1857928, HPA062839: AB_2684878" "prognostic unfavorable (6.43e-4)" "unprognostic (2.54e-2)" "unprognostic (4.09e-2)" "unprognostic (2.95e-2)" "unprognostic (2.68e-1)" "unprognostic (4.79e-2)" "unprognostic (1.90e-1)" "unprognostic (2.66e-1)" "unprognostic (1.64e-1)" "unprognostic (8.59e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (2.61e-2)" "unprognostic (8.29e-4)" "unprognostic (4.54e-3)" "unprognostic (2.64e-1)" "unprognostic (1.08e-1)" "unprognostic (1.03e-2)" 0.1 0.0 0.0 1.0 0.0 0.0 12.3 0.0 0.3 6.9 0.0 8.0 4.0 1.7 16.1 20.4 8.5 3.3 0.0 0.0 0.0 6.3 0.4 5.6 0.0 0.0 0.0 0.0 11.1 9.3 0.8 6.7 0.0 23.2 9.2 0.0 14.8 7.2 0.0 28.6 4.3 0.4 0.0 0.1 9.8 0.3 0.0 2.9 10.2 0.0 4.6 7.7 10.4 0.0 39.3 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 28.0 18.9 0.0 0.0 0.1 0.0 46.3 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.7 0.0 0.3 0.2 37.9 0.0 0.0 0.0 0.1 0.0 68.9 1.9 0.0 0.0 15.0 0.0 4.4 79.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 32.1 13.0 0.3 0.0 24.3 10.5 7.6 20.5 0.0 14.4 6.1 0.7 17.2 20.8 11.0 0.0 14.0 0.2 10.3 5.9 7.5 2.4 20.0 1.5 0.8 1.2 0.0 0.8 5.5 7.1 0.8 15.3 20.7 0.0 0.0 0.0 0.0 1.4 0.0 1.3 9.8 2.0 0.0 1.1 9.3 0.0 0.3 1.8 0.0 0.6 0.0 0.0 2.0 0.5 8.8 8.5 0.0 1.3 9.3 5.7 0.1 28.8 0.0 0.0 0.5 1.0 0.1 0.0 27.1 26.0 19.8 0.3 0.1 11.0 6.3 GSTA2 GST2 ENSG00000244067 "Glutathione S-transferase alpha 2" P09210 6 52750087-52763475 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 696.0;liver: 2058.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 201.6;Distal tubular cells: 213.2;Exocrine glandular cells: 239.6;Pancreatic endocrine cells: 334.7;Proximal enterocytes: 367.0;Proximal tubular cells: 1186.6;Respiratory ciliated cells: 435.5" "Group enriched" "Detected in many" 16 "liver cancer: 124.6;renal cancer: 48.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "CACO-2: 25.9;Hep G2: 20.0" "HPA004342, HPA048934, HPA053817" Supported Supported Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA004342: AB_1078987, HPA048934: AB_2680563, HPA053817: AB_2630367" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (2.72e-2)" "unprognostic (1.15e-1)" "unprognostic (6.43e-3)" "unprognostic (2.41e-1)" "unprognostic (1.30e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (4.34e-2)" "unprognostic (1.91e-1)" "unprognostic (6.54e-2)" 0.4 4.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.6 149.5 0.0 0.7 0.1 2.5 109.4 0.0 0.0 0.0 696.0 2058.5 4.8 0.1 0.0 0.0 0.2 299.2 0.0 0.0 0.1 0.0 3.8 0.1 0.0 0.5 0.0 0.0 0.0 115.5 0.0 0.0 0.0 11.7 44.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 25.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.2 0.0 20.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 1.7 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.6 0.0 0.0 0.3 0.6 0.5 0.5 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 1.7 0.0 0.2 1.5 0.0 0.0 0.1 0.1 0.0 201.6 31.1 16.5 0.0 0.0 0.0 0.1 213.2 8.1 6.9 0.0 0.0 0.6 0.0 0.0 0.0 239.6 0.2 0.5 7.7 0.0 0.0 37.2 0.7 124.2 0.1 0.0 0.0 13.7 2.0 2.2 0.0 14.6 1.2 5.1 0.0 0.0 5.2 0.0 0.0 0.0 0.1 334.7 18.8 0.4 0.0 3.9 367.0 1186.6 435.5 0.0 0.0 0.0 1.5 1.9 0.7 0.0 0.0 0.0 2.6 10.4 30.1 1.3 GSTM4 ENSG00000168765 "Glutathione S-transferase mu 4" Q03013 1 109656099-109674836 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 149.5" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 382.8;Proximal tubular cells: 109.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "eosinophil: 351.7" "Lineage enriched" "Detected in all" 9 "granulocytes: 351.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048652, HPA055972, HPA055973" Approved Approved "Cytokinetic bridge,Cytosol" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" Cytosol "Cytokinetic bridge" "HPA048652: AB_2680478, HPA055972: AB_2682992, HPA055973: AB_2682993" "prognostic favorable (9.96e-5)" "unprognostic (1.96e-3)" "unprognostic (7.49e-2)" "unprognostic (9.92e-3)" "unprognostic (1.48e-1)" "unprognostic (1.08e-2)" "unprognostic (8.47e-2)" "unprognostic (3.48e-2)" "unprognostic (1.20e-1)" "unprognostic (4.76e-2)" "unprognostic (3.73e-1)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (1.92e-2)" "unprognostic (2.20e-1)" "unprognostic (1.41e-1)" "unprognostic (2.47e-2)" 22.3 31.1 19.7 15.3 23.7 5.9 22.5 19.1 23.8 24.5 40.0 45.4 149.5 22.6 24.3 31.3 22.2 17.8 33.5 19.2 19.9 45.9 41.2 14.6 11.8 20.7 20.9 42.9 21.2 57.8 18.6 7.6 20.2 25.8 38.5 12.5 21.2 41.0 92.4 20.6 99.4 25.7 21.1 30.2 28.8 15.1 20.1 9.9 27.7 45.5 15.6 36.8 28.8 20.2 13.5 6.0 10.5 78.9 23.0 35.1 13.4 4.3 34.1 9.8 12.8 43.3 1.5 12.5 16.1 19.1 19.3 13.6 27.1 14.4 6.2 18.9 0.0 27.4 23.5 38.8 37.1 9.5 31.8 22.3 14.0 12.6 0.0 27.5 8.1 31.7 12.8 18.4 6.9 12.7 8.1 41.9 8.2 56.3 31.9 16.9 5.8 18.5 38.8 9.6 7.4 17.6 0.2 68.2 54.9 7.8 18.6 20.1 3.6 11.4 44.0 12.5 6.3 27.0 51.4 1.1 37.1 13.9 32.5 11.9 14.5 351.7 12.2 14.5 7.4 17.0 9.3 14.1 37.8 14.9 8.9 10.7 1.8 12.8 3.6 12.6 14.1 12.6 19.7 23.7 19.1 23.8 19.2 19.9 20.7 20.9 20.2 21.1 20.1 20.2 6.9 9.6 2.7 11.4 9.9 18.1 27.3 17.9 18.8 6.2 14.7 19.0 30.2 21.5 9.5 31.3 0.0 21.0 13.9 53.0 101.8 45.9 3.0 4.5 10.8 8.6 7.2 4.2 3.3 57.7 18.6 22.9 13.3 5.4 21.0 13.3 14.3 35.7 35.6 5.0 3.3 45.9 6.1 17.2 26.0 6.4 30.1 14.9 40.9 2.8 14.8 23.9 17.5 5.0 3.4 35.4 38.6 24.8 13.3 6.7 382.8 109.8 7.5 5.4 32.9 15.3 23.2 7.0 7.3 23.0 15.3 8.8 11.2 12.6 96.7 26.9 GSTM5 ENSG00000134201 "Glutathione S-transferase mu 5" P46439 1 109711780-109775428 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "breast: 929.9" "Group enriched" "Detected in many" 4 "Fibroblasts: 59.0;Leydig cells: 143.5;Muller glia cells: 213.3;Peritubular cells: 127.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "plasmacytoid DC: 3.9" "Lineage enriched" "Detected in single" 4 "dendritic cells: 3.9" "Group enriched" "Detected in some" 5 "fHDF/TERT166: 21.6;HHSteC: 10.3;HSkMC: 10.9" "HPA055972, HPA055973" Approved Uncertain "Cytokinetic bridge,Cytosol" Yes NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 5: Breast - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Cytosol "Cytokinetic bridge" "HPA055972: AB_2682992, HPA055973: AB_2682993" "unprognostic (1.46e-2)" "unprognostic (8.64e-3)" "unprognostic (5.58e-2)" "unprognostic (1.42e-1)" "unprognostic (5.34e-3)" "unprognostic (8.09e-2)" "unprognostic (9.64e-4)" "unprognostic (1.31e-2)" "unprognostic (1.44e-1)" "unprognostic (9.16e-2)" "unprognostic (3.31e-1)" "unprognostic (1.92e-2)" "unprognostic (1.42e-2)" "unprognostic (3.74e-2)" "unprognostic (4.39e-2)" "unprognostic (3.03e-3)" "unprognostic (1.40e-1)" 21.7 6.4 60.3 4.6 65.3 0.5 929.9 60.4 71.1 72.5 62.9 13.9 2.3 35.1 32.9 11.6 62.0 25.8 17.0 61.4 54.5 5.5 3.9 18.0 5.0 57.2 55.4 213.9 4.7 0.2 9.4 0.8 56.7 27.9 7.8 12.4 7.9 32.6 3.9 12.2 10.3 26.5 60.1 7.7 13.2 11.4 53.5 6.4 9.1 14.0 6.5 27.9 47.6 58.6 0.0 0.0 0.0 0.0 1.7 1.6 0.4 1.3 0.0 0.3 0.2 0.0 0.0 0.1 0.0 21.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.8 0.0 0.0 10.3 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.0 0.1 0.0 0.6 0.0 3.9 0.9 0.7 60.3 65.3 60.4 71.1 61.4 54.5 57.2 55.4 56.7 60.1 53.5 58.6 2.5 0.0 0.5 32.3 0.0 6.6 0.9 0.2 0.0 2.0 0.5 0.8 0.9 1.5 0.0 0.0 2.1 0.0 0.3 0.0 0.0 0.0 9.0 0.3 12.3 2.2 0.0 2.1 0.1 0.0 0.1 59.0 1.1 0.3 0.0 0.6 5.7 0.0 0.3 0.0 0.5 0.1 0.0 0.6 9.3 15.1 143.5 0.6 10.6 1.9 0.0 213.3 0.0 2.0 0.3 0.0 0.0 127.2 0.1 0.1 0.1 0.0 0.0 6.8 26.3 2.3 9.4 2.0 1.8 1.0 6.5 0.0 2.8 2.4 0.1 0.6 GUCY1A2 "GC-SA2, GUC1A2" ENSG00000152402 "Guanylate cyclase 1 soluble subunit alpha 2" P33402 11 106674019-107018476 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.4;placenta: 17.9" "Group enriched" "Detected in many" 4 "Excitatory neurons: 353.8;Inhibitory neurons: 141.8;Oligodendrocyte precursor cells: 208.6;Sertoli cells: 105.2;Smooth muscle cells: 107.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 11.8;BJ hTERT+ SV40 Large T+ RasG12V: 13.4;HBF TERT88: 7.1;TIME: 4.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009534 Uncertain NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB009534: AB_2279509" "unprognostic (7.53e-2)" "unprognostic (6.67e-2)" "unprognostic (7.99e-2)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (1.22e-2)" "unprognostic (1.23e-2)" "unprognostic (1.24e-1)" "unprognostic (6.53e-3)" "unprognostic (9.70e-3)" "unprognostic (8.00e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (3.02e-5)" "unprognostic (2.48e-4)" "unprognostic (1.62e-1)" "unprognostic (3.50e-2)" "unprognostic (1.09e-2)" 3.4 2.0 5.3 0.6 18.4 0.0 1.9 1.6 13.8 12.7 0.0 0.7 0.2 12.3 3.1 0.4 5.9 1.5 2.7 7.1 3.9 1.8 1.7 4.6 0.7 4.7 2.6 1.2 4.3 0.6 0.5 17.9 4.9 1.8 0.5 3.5 0.6 6.8 1.8 0.6 0.4 13.1 0.4 6.0 0.3 1.7 8.6 0.2 1.4 3.6 0.3 0.9 2.8 7.4 0.0 0.2 4.0 0.0 0.2 2.4 2.2 0.3 11.8 1.5 13.4 0.0 0.0 0.0 0.0 0.9 0.4 0.0 0.1 0.0 7.1 0.0 1.1 0.0 0.1 0.0 0.2 0.0 1.6 0.6 0.0 1.8 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.4 3.6 0.0 0.7 0.5 0.8 0.2 4.6 3.7 3.0 0.8 1.2 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 18.4 1.6 13.8 7.1 3.9 4.7 2.6 4.9 0.4 8.6 7.4 29.5 0.0 0.5 20.2 0.5 1.7 2.2 0.0 1.2 24.0 0.4 0.9 5.1 0.0 0.0 3.7 12.5 0.1 0.0 0.1 0.0 5.8 2.5 0.9 24.2 12.5 0.0 2.7 353.8 0.2 0.0 8.2 0.0 1.1 0.0 42.7 2.2 0.2 0.4 18.5 141.8 0.0 0.0 0.8 1.5 6.5 24.5 1.1 3.6 18.7 0.0 29.3 0.0 208.6 10.7 0.3 0.0 25.2 1.2 2.4 0.0 0.1 0.0 4.8 105.2 20.7 107.0 1.6 1.5 0.7 1.1 0.3 0.5 19.6 0.0 1.5 HBA2 HBA-T2 ENSG00000188536 "Hemoglobin subunit alpha 2" P69905 16 172876-173710 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Oxygen transport, Transport" "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 38218.6" "Cell type enriched" "Detected in many" 22 "Erythroid cells: 198314.0" "Cancer enhanced" "Detected in all" "glioma: 59.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 315.1;neutrophil: 955.3;plasmacytoid DC: 486.7" "Group enriched" "Detected in all" 7 "dendritic cells: 486.7;granulocytes: 955.3" "Group enriched" "Detected in some" 18 "HEL: 1196.2;K-562: 328.3" "CAB038417, HPA043780" Enhanced NA NA 14000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "CAB038417: , HPA043780: AB_2678667" "unprognostic (1.57e-1)" "unprognostic (7.02e-2)" "unprognostic (2.59e-2)" "unprognostic (2.13e-1)" "unprognostic (3.59e-1)" "unprognostic (3.18e-1)" "unprognostic (3.39e-2)" "unprognostic (2.12e-1)" "unprognostic (4.99e-2)" "unprognostic (4.43e-1)" "unprognostic (1.09e-2)" "unprognostic (1.19e-2)" "unprognostic (1.72e-3)" "unprognostic (1.36e-1)" "unprognostic (2.11e-1)" "unprognostic (4.73e-2)" "unprognostic (8.92e-2)" 1592.0 322.5 162.6 186.3 292.4 38218.6 545.3 268.0 377.0 573.3 570.7 254.0 21.6 85.9 5.9 432.5 570.5 147.6 2590.3 86.6 156.5 2302.8 1853.6 4204.3 9.7 210.6 249.2 288.5 141.3 11.4 807.8 3618.9 260.6 302.7 26.7 4.0 305.4 131.9 568.3 188.5 154.3 12.9 316.4 8125.4 264.0 185.0 185.4 34.6 1192.5 1744.6 10.1 325.2 632.8 179.9 0.0 0.2 0.0 0.0 0.0 0.7 0.4 0.4 0.1 0.0 0.0 3.2 0.0 1.9 4.9 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.6 1196.2 0.5 0.0 0.0 0.2 1.7 0.4 0.1 0.4 0.0 0.0 0.0 0.1 328.3 0.0 0.1 0.6 0.0 0.3 0.1 0.5 0.0 0.0 0.0 43.4 0.0 0.9 11.9 9.7 1.1 0.0 0.0 0.1 1.4 0.2 5.6 0.0 0.3 0.4 0.0 0.4 0.0 0.0 0.3 0.6 0.2 119.6 28.1 315.1 99.6 1.7 3.7 39.2 8.5 7.1 42.5 19.1 22.8 73.9 955.3 49.5 3.3 486.7 1.0 15003.3 162.6 292.4 268.0 377.0 86.6 156.5 210.6 249.2 260.6 316.4 185.4 179.9 184.7 3.2 1.5 0.0 97.6 44.4 0.4 0.1 0.6 1.7 20.2 22.2 6.8 70.1 0.7 0.0 0.0 0.0 162.2 6.9 54.8 0.0 3.4 0.6 0.8 50.9 3.0 198314.0 0.0 0.0 0.0 241.0 4.1 0.9 1.3 0.3 142.8 131.2 0.0 0.0 0.0 7.5 4.1 770.6 149.6 16.9 0.0 402.9 8790.3 0.0 37.5 2.3 954.7 0.0 0.0 0.0 3.6 0.0 0.3 0.2 0.1 29.6 2.5 58.6 0.0 25.2 171.5 1.0 9.9 1.1 44.6 0.0 306.3 0.1 5.0 0.1 HDAC6 "FLJ16239, HD6, JM21, KIAA0901, PPP1R90" ENSG00000094631 "Histone deacetylase 6" Q9UBN7 X 48801377-48824982 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Autophagy, Transcription, Transcription regulation" "Actin-binding, Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 88.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003714, CAB004236, HPA026321" Supported Supported Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "CAB004236: AB_627708, HPA003714: AB_1850544, HPA026321: AB_1850546" "unprognostic (9.53e-2)" "unprognostic (1.59e-1)" "unprognostic (2.66e-2)" "unprognostic (2.42e-2)" "unprognostic (2.82e-2)" "unprognostic (4.11e-3)" "unprognostic (2.17e-2)" "unprognostic (1.16e-1)" "unprognostic (7.68e-2)" "unprognostic (2.83e-1)" "unprognostic (1.16e-3)" "unprognostic (2.33e-2)" "unprognostic (6.10e-2)" "unprognostic (1.47e-1)" "unprognostic (6.60e-2)" "unprognostic (2.34e-1)" "prognostic favorable (3.34e-4)" 21.9 26.0 26.6 14.2 30.7 22.9 23.6 31.1 54.2 29.6 29.8 27.8 17.8 26.8 10.6 24.4 28.2 11.1 26.0 26.7 33.0 57.9 97.3 25.2 15.6 32.6 32.7 32.5 26.3 22.3 45.6 13.8 33.9 24.4 16.1 27.9 21.6 12.2 26.1 21.4 28.0 15.3 28.9 29.4 26.6 53.8 30.6 18.8 27.1 16.1 15.1 23.7 22.8 31.0 31.0 25.7 49.6 19.1 20.2 16.6 33.4 14.4 12.4 27.2 26.2 24.9 25.7 29.9 13.8 17.1 34.6 21.3 30.6 15.5 23.2 27.7 19.1 40.7 32.2 26.0 18.3 19.2 60.4 25.7 25.1 21.5 25.3 24.8 23.5 37.4 45.9 31.9 17.7 10.9 27.0 29.3 18.5 14.2 24.5 23.1 53.5 31.3 15.8 13.3 25.9 25.3 29.5 8.7 17.4 63.4 36.1 17.5 19.1 21.5 26.7 29.3 14.2 29.6 31.3 21.3 21.3 24.0 21.5 0.0 5.1 5.8 4.7 8.3 3.4 3.7 3.3 3.4 7.6 5.3 3.1 2.9 2.5 3.6 11.7 8.3 4.0 4.9 26.6 30.7 31.1 54.2 26.7 33.0 32.6 32.7 33.9 28.9 30.6 31.0 11.4 19.2 25.1 20.9 12.5 7.5 10.2 8.8 6.2 37.6 10.7 10.4 10.6 8.6 17.5 18.4 50.1 11.5 12.6 21.4 19.6 7.9 48.1 10.0 13.0 10.3 14.4 11.4 15.2 7.4 12.3 10.7 21.9 13.2 6.3 22.5 13.6 51.9 11.1 40.4 18.4 15.5 10.2 12.3 9.8 18.4 14.0 13.2 5.4 10.3 12.7 21.9 18.6 17.1 19.0 7.2 13.2 11.3 12.8 7.1 17.8 47.6 12.4 34.0 13.1 15.5 11.1 88.4 41.7 8.6 5.8 9.7 9.7 21.8 16.2 7.2 HECW2 "KIAA1301, NEDL2" ENSG00000138411 "HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2" Q9P2P5 2 196189099-196593684 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 331.5;Hepatic stellate cells: 99.2;Inhibitory neurons: 375.4;Oligodendrocyte precursor cells: 143.2;Oligodendrocytes: 460.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 4.7;non-classical monocyte: 3.7" "Group enriched" "Detected in many" 8 "granulocytes: 4.7;monocytes: 3.7" "Cell line enhanced" "Detected in many" "HDLM-2: 30.1;hTEC/SVTERT24-B: 16.3;HUVEC TERT2: 20.9;SCLC-21H: 31.6;TIME: 26.3;U-138 MG: 21.7" "Low region specificity" "Detected in all" HPA034609 Enhanced NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA034609: AB_10669993" "unprognostic (2.65e-2)" "unprognostic (3.89e-1)" "unprognostic (1.42e-1)" "unprognostic (9.00e-3)" "unprognostic (2.55e-1)" "unprognostic (4.28e-2)" "unprognostic (7.63e-3)" "unprognostic (1.23e-1)" "unprognostic (2.61e-2)" "unprognostic (7.05e-2)" "unprognostic (4.16e-2)" "unprognostic (2.27e-1)" "prognostic unfavorable (5.18e-5)" "unprognostic (8.05e-3)" "unprognostic (5.20e-2)" "unprognostic (1.49e-1)" "unprognostic (4.48e-2)" 4.1 1.5 2.4 1.2 3.5 0.1 1.7 4.4 6.1 2.2 0.0 0.4 0.4 0.8 0.3 3.1 3.5 2.1 8.1 3.3 0.0 1.6 2.7 5.3 2.0 1.1 0.8 0.2 0.6 4.3 1.2 7.4 2.1 0.4 0.4 2.7 0.9 0.5 1.4 0.8 0.5 1.3 0.0 6.0 0.9 3.5 1.7 0.8 3.8 3.5 2.4 1.0 0.6 8.2 0.1 1.4 2.3 0.0 1.4 4.2 1.6 2.7 7.3 2.1 2.6 0.3 0.1 1.4 0.5 13.4 3.3 3.2 0.9 0.1 4.5 30.1 1.6 0.0 2.3 0.2 0.2 0.5 0.3 1.0 1.3 16.3 5.7 4.1 20.9 0.0 0.2 0.1 6.7 1.8 0.0 0.7 2.5 0.2 1.0 0.0 0.5 0.0 0.1 0.0 31.6 2.5 2.0 0.5 0.0 0.4 0.1 0.2 26.3 21.7 1.4 4.6 0.7 0.2 0.0 1.3 5.4 0.1 0.2 0.1 0.3 0.8 0.0 1.1 0.0 0.4 0.0 0.0 0.4 0.5 0.0 0.0 4.7 0.0 3.7 0.0 0.0 0.1 2.4 3.5 4.4 6.1 3.3 0.0 1.1 0.8 2.1 0.0 1.7 8.2 61.2 0.0 12.1 12.7 3.6 2.2 0.3 0.1 3.4 9.5 1.1 0.8 18.7 0.0 0.1 0.0 0.0 0.2 0.7 0.6 0.0 0.1 11.1 0.4 1.6 34.2 2.4 0.0 331.5 0.0 0.3 4.2 0.5 0.3 1.3 4.9 99.2 1.5 0.1 0.0 375.4 0.6 0.0 7.2 3.0 5.3 0.0 1.4 3.6 14.0 1.2 12.0 0.0 143.2 460.7 0.1 0.0 2.6 3.4 0.4 0.0 0.1 1.0 1.1 0.0 1.2 2.2 0.5 6.1 9.2 1.6 0.1 1.4 0.7 0.1 0.6 HEPH "CPL, KIAA0698" ENSG00000089472 Hephaestin Q9BQS7 X 66162549-66268867 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 81.9;smooth muscle: 82.7" "Cell type enhanced" "Detected in many" "Astrocytes: 78.0;Distal enterocytes: 211.0;Intestinal goblet cells: 95.6;Paneth cells: 96.9;Proximal enterocytes: 156.2;Undifferentiated cells: 72.4" "Cancer enhanced" "Detected in all" "colorectal cancer: 37.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 28.5;HEL: 25.4;HSkMC: 36.0;K-562: 72.5;LHCN-M2: 28.5;SuSa: 68.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA005824 Approved NA NA 3700000 "Cluster 37: Intestine - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA005824: AB_1850603" "unprognostic (3.10e-1)" "unprognostic (1.85e-1)" "unprognostic (1.25e-2)" "unprognostic (4.25e-2)" "unprognostic (1.29e-3)" "unprognostic (2.25e-1)" "unprognostic (4.94e-2)" "unprognostic (6.17e-2)" "unprognostic (1.40e-2)" "unprognostic (3.35e-1)" "unprognostic (2.40e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (7.00e-6)" "unprognostic (3.08e-2)" "unprognostic (4.46e-2)" "unprognostic (1.04e-1)" "unprognostic (1.17e-2)" 8.2 19.1 18.2 14.7 25.0 0.0 8.3 20.8 19.2 23.8 8.7 81.9 79.0 34.7 14.4 11.9 14.2 38.7 36.0 16.7 21.2 8.1 3.5 12.3 3.6 22.3 24.4 22.1 2.3 1.4 3.7 1.3 20.4 24.3 77.6 15.0 7.6 31.8 0.8 4.8 81.6 82.7 18.8 11.1 12.4 3.5 21.7 1.3 5.1 3.2 2.6 19.5 10.1 21.0 0.0 0.0 28.5 2.3 0.0 0.1 0.8 7.3 0.4 0.0 0.0 17.4 0.0 0.0 0.1 15.1 0.0 0.0 0.0 0.0 0.0 8.3 0.0 25.4 0.0 0.0 0.3 0.2 0.1 36.0 0.0 0.0 0.0 9.9 0.0 0.0 72.5 0.6 28.5 0.0 0.0 0.6 14.1 4.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 68.6 0.0 0.0 0.7 16.2 1.2 0.1 1.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 25.0 20.8 19.2 16.7 21.2 22.3 24.4 20.4 18.8 21.7 21.0 2.5 0.0 0.0 78.0 0.5 0.9 0.0 0.0 0.0 1.0 0.9 6.0 24.1 0.0 0.0 0.0 0.0 0.0 0.1 211.0 0.0 0.3 0.6 1.3 15.1 4.1 40.8 0.0 0.3 1.1 0.0 12.6 0.0 1.2 0.0 1.1 6.4 0.0 0.2 0.0 2.9 95.6 0.0 0.0 1.9 1.5 11.5 0.3 0.0 6.5 0.0 26.1 0.0 3.5 36.2 5.0 96.9 29.7 0.0 0.3 156.2 0.0 0.7 1.3 6.6 4.4 9.8 0.0 0.3 0.3 0.6 0.0 0.5 6.9 72.4 0.2 HID1 "C17orf28, DMC1, HID-1" ENSG00000167861 "HID1 domain containing" Q8IV36 17 74950742-74973166 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 111.2" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 71.4;Intestinal goblet cells: 89.5;Paneth cells: 87.8;Proximal enterocytes: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 115.9;OE19: 99.2;SH-SY5Y: 56.7;SK-BR-3: 172.6;T-47d: 101.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031406 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus, Cytosol" "HPA031406: AB_2673866" "unprognostic (7.41e-2)" "unprognostic (1.96e-1)" "unprognostic (2.69e-1)" "unprognostic (2.22e-3)" "unprognostic (4.47e-3)" "unprognostic (6.79e-3)" "unprognostic (4.00e-2)" "unprognostic (1.11e-1)" "unprognostic (2.78e-1)" "unprognostic (3.90e-1)" "unprognostic (1.54e-3)" "unprognostic (1.37e-1)" "prognostic favorable (3.13e-5)" "unprognostic (1.17e-1)" "unprognostic (2.83e-1)" "unprognostic (1.09e-1)" "prognostic favorable (1.34e-4)" 13.2 5.8 21.7 6.6 26.9 2.0 23.2 41.5 33.3 19.9 2.8 17.9 39.1 11.9 29.1 5.5 19.0 21.6 12.4 22.0 24.3 12.3 4.4 20.4 5.3 27.4 22.7 3.0 111.2 14.4 44.0 20.1 30.3 36.2 17.9 8.7 86.2 20.2 4.6 7.6 27.3 6.3 10.4 16.7 68.7 6.8 25.4 2.8 16.8 5.7 6.3 12.3 7.6 39.1 5.2 11.4 1.3 15.8 0.0 0.0 2.7 0.0 0.6 1.1 1.0 10.6 5.8 0.0 1.0 0.0 1.4 4.9 14.5 1.0 0.8 0.0 11.4 0.1 0.3 10.1 2.7 0.0 1.1 0.2 6.0 0.1 2.4 0.3 26.0 3.8 0.7 4.0 0.0 115.9 0.7 0.2 0.4 99.2 7.1 0.2 0.0 21.8 14.5 44.8 21.1 56.7 0.0 172.6 0.0 3.6 101.2 0.0 0.5 0.1 1.4 0.4 0.0 2.0 0.3 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.5 0.6 0.9 0.7 0.0 0.1 1.0 1.1 0.0 0.0 0.0 2.6 0.0 0.4 21.7 26.9 41.5 33.3 22.0 24.3 27.4 22.7 30.3 10.4 25.4 39.1 21.4 0.0 5.5 4.9 4.6 1.5 2.6 3.1 0.6 14.3 20.4 12.3 3.8 4.3 8.6 0.0 0.0 26.3 1.1 16.0 3.9 19.0 0.4 10.2 3.0 19.1 35.3 0.0 16.1 26.9 1.7 1.0 71.4 20.3 0.0 1.1 20.7 0.4 2.5 20.2 15.5 89.5 16.2 0.8 0.4 1.0 0.9 0.7 7.2 6.5 0.6 2.8 0.0 8.0 50.9 22.9 87.8 0.0 22.7 17.8 107.4 0.5 6.5 4.4 0.0 1.5 1.8 0.4 2.1 0.5 0.4 35.0 1.8 0.1 15.6 13.9 HINT2 ENSG00000137133 "Histidine triad nucleotide binding protein 2" Q9BX68 9 35812960-35815354 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 633.9;Hepatocytes: 457.4;Proximal tubular cells: 578.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020961, HPA059109" Supported Enhanced Mitochondria "Intracellular and membrane" NA NA 110000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA020961: AB_1850715, HPA059109: AB_2683906" "unprognostic (9.64e-3)" "unprognostic (1.53e-2)" "unprognostic (3.02e-1)" "unprognostic (3.01e-2)" "unprognostic (5.51e-2)" "unprognostic (3.97e-2)" "unprognostic (1.07e-1)" "unprognostic (2.38e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.66e-4)" "unprognostic (3.71e-3)" "unprognostic (2.87e-2)" "prognostic favorable (2.97e-9)" "unprognostic (4.29e-2)" "unprognostic (1.41e-1)" "unprognostic (8.78e-2)" "unprognostic (1.72e-1)" 50.8 79.5 41.7 15.5 43.9 27.0 48.5 44.9 46.8 23.2 40.3 42.6 34.9 25.9 48.6 27.5 29.9 14.9 87.4 39.8 43.1 91.1 169.2 30.2 21.0 43.8 42.5 19.2 65.9 72.6 41.2 17.6 42.0 33.9 34.2 20.4 39.7 26.1 80.1 33.4 34.2 20.1 43.9 33.8 56.9 29.8 47.3 38.8 38.4 85.5 23.8 30.6 24.2 44.0 30.3 76.1 47.1 45.6 29.0 24.3 33.2 27.8 39.2 42.3 46.1 49.9 31.1 39.9 31.7 25.3 59.8 29.3 21.2 40.9 44.1 87.8 40.7 42.2 64.1 45.8 68.1 25.1 40.0 27.3 36.8 40.2 64.8 16.7 33.2 91.4 25.5 117.4 34.0 60.3 61.3 31.3 21.4 70.0 138.7 60.8 33.1 53.6 61.5 21.5 38.4 46.4 36.0 42.7 49.6 27.5 45.9 44.6 16.5 22.0 37.7 30.4 35.7 107.0 127.3 57.4 49.8 32.2 36.2 41.0 77.5 4.7 68.9 58.5 62.4 98.9 73.7 69.8 113.4 96.7 56.4 58.6 7.6 66.8 56.9 246.1 107.3 81.2 41.7 43.9 44.9 46.8 39.8 43.1 43.8 42.5 42.0 43.9 47.3 44.0 49.3 22.4 17.5 5.2 57.9 45.4 63.4 137.6 49.5 39.8 99.1 105.8 115.1 130.1 68.3 80.9 20.9 154.9 69.3 148.2 633.9 115.5 67.3 83.9 28.6 47.8 96.0 100.8 1.7 172.1 71.7 53.2 52.5 44.6 18.4 43.5 63.1 457.4 113.9 20.2 2.5 127.4 126.1 61.1 51.4 128.0 40.4 47.7 120.9 1.9 74.1 123.7 87.6 1.5 4.5 85.6 157.5 44.8 77.7 40.7 181.4 578.1 105.1 45.5 46.0 54.2 72.6 38.4 77.4 64.7 45.9 56.8 51.0 85.1 126.7 84.8 HJV "haemojuvelin, hemojuvelin, HFE2, HFE2A, JH, RGMC" ENSG00000168509 "Hemojuvelin BMP co-receptor" Q6ZVN8 1 146017468-146036746 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "liver: 239.6;skeletal muscle: 591.1;tongue: 291.6" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 96 "liver cancer: 87.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 1.5;K-562: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA 69000 "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.30e-1)" "unprognostic (6.98e-4)" "unprognostic (7.06e-2)" "unprognostic (1.11e-2)" "unprognostic (2.77e-3)" "unprognostic (2.55e-1)" "unprognostic (8.50e-2)" "unprognostic (2.36e-1)" "unprognostic (7.14e-2)" "unprognostic (1.18e-1)" "unprognostic (8.96e-8)" "unprognostic (6.61e-2)" "unprognostic (2.72e-1)" "unprognostic (1.76e-2)" 0.1 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 7.9 0.1 0.1 67.5 0.0 0.1 0.2 239.6 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.1 2.2 0.0 0.0 5.9 0.0 591.1 0.4 0.1 0.2 0.4 0.2 0.1 1.6 0.1 0.3 0.1 291.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.4 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HMGCLL1 "bA418P12.1, DKFZP434G1411" ENSG00000146151 "3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1" Q8TB92 6 55434373-55579197 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.6" "Cell type enhanced" "Detected in some" "Astrocytes: 49.9;Excitatory neurons: 80.7;Inhibitory neurons: 76.2;Oligodendrocytes: 23.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (2.74e-3)" "unprognostic (1.54e-2)" "unprognostic (4.08e-3)" "unprognostic (6.11e-2)" "unprognostic (1.41e-1)" "unprognostic (9.54e-3)" "unprognostic (8.97e-3)" "unprognostic (2.12e-2)" "unprognostic (9.27e-3)" "unprognostic (4.11e-2)" "unprognostic (1.18e-4)" "unprognostic (3.13e-3)" "unprognostic (7.57e-2)" "unprognostic (2.55e-1)" "unprognostic (1.52e-1)" 1.4 3.6 6.1 0.2 5.9 0.0 1.4 5.9 5.2 0.8 0.0 0.8 0.2 0.2 0.0 1.0 0.4 0.6 1.8 5.5 10.6 0.9 0.7 2.6 0.3 5.6 6.3 0.4 1.6 0.1 4.7 6.2 6.6 3.0 0.8 4.5 0.8 1.0 1.1 0.1 0.9 0.5 9.2 0.0 1.0 2.6 8.3 0.6 0.4 2.8 0.2 0.9 0.7 9.4 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.2 0.0 0.0 0.0 1.1 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 5.9 5.9 5.2 5.5 10.6 5.6 6.3 6.6 9.2 8.3 9.4 0.6 0.0 1.3 49.9 0.0 0.0 0.0 0.0 1.2 15.1 3.7 2.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.5 0.0 0.0 80.7 0.0 0.0 5.8 0.0 0.0 0.0 3.5 3.9 0.0 0.1 0.0 76.2 0.0 0.0 0.3 0.0 1.3 0.3 0.1 0.0 15.0 0.0 1.5 0.0 5.5 23.5 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.9 5.6 1.3 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 HNMT ENSG00000150540 "Histamine N-methyltransferase" P50135 2 137964020-138016364 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 245.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 299.3;Kupffer cells: 263.7;Proximal tubular cells: 268.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 21 "classical monocyte: 110.9;intermediate monocyte: 89.8;myeloid DC: 68.3;non-classical monocyte: 52.2" "Group enriched" "Detected in many" 23 "dendritic cells: 68.3;monocytes: 110.9" "Cell line enhanced" "Detected in many" "Hep G2: 227.2;HSkMC: 87.9;RT4: 117.1;SuSa: 107.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035480, HPA035481, HPA073754" Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA 130000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Cytosol" Centrosome "HPA035480: AB_2674645, HPA035481: AB_10672094, HPA073754: " "unprognostic (1.32e-1)" "unprognostic (3.53e-1)" "unprognostic (5.44e-2)" "unprognostic (2.09e-2)" "unprognostic (2.81e-1)" "unprognostic (2.33e-1)" "unprognostic (2.29e-2)" "unprognostic (6.02e-2)" "unprognostic (5.69e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (3.41e-4)" "unprognostic (5.24e-2)" "unprognostic (1.34e-2)" "unprognostic (1.76e-2)" "unprognostic (5.34e-2)" "unprognostic (1.21e-1)" "prognostic favorable (4.68e-4)" 70.4 18.2 13.0 41.7 13.3 12.6 62.3 13.1 18.8 57.3 19.2 53.9 29.3 62.8 27.1 17.5 34.5 68.7 21.7 15.6 19.1 109.7 245.9 49.0 35.1 16.0 15.3 91.0 29.0 40.2 9.5 46.8 18.1 37.0 56.4 6.1 30.5 44.3 5.9 17.4 29.1 33.1 16.1 37.5 29.1 10.3 14.5 8.2 14.6 11.9 16.4 49.7 24.5 22.2 0.7 0.9 5.6 14.6 61.9 64.6 0.4 3.9 6.2 0.4 2.3 29.7 15.7 0.9 50.2 17.0 0.8 1.1 11.9 0.0 0.1 0.7 4.9 0.2 44.5 227.2 28.0 0.3 0.6 87.9 0.1 21.5 0.0 4.7 15.9 0.1 0.5 0.7 47.4 3.7 0.0 0.5 28.1 39.3 5.6 0.5 1.5 0.2 67.9 117.1 0.1 0.8 22.1 28.4 0.1 107.9 1.0 53.2 4.8 4.8 11.8 6.2 16.3 0.4 0.3 0.7 20.9 27.8 3.3 1.3 110.9 0.7 0.5 89.8 0.3 1.8 0.2 0.2 68.3 0.5 0.3 0.4 3.9 0.5 52.2 1.5 0.7 32.6 13.0 13.3 13.1 18.8 15.6 19.1 16.0 15.3 18.1 16.1 14.5 22.2 15.5 28.9 44.1 9.4 5.0 35.6 81.5 64.6 30.7 0.7 78.1 65.4 2.2 133.0 88.9 60.7 0.0 54.9 2.6 59.4 123.3 122.1 1.5 28.3 50.6 9.4 16.4 16.8 16.8 48.0 81.6 54.2 20.9 115.3 0.0 17.4 19.2 165.7 299.3 0.0 13.8 67.8 24.4 263.7 97.2 4.2 131.4 127.4 56.9 31.9 122.0 25.5 4.1 45.8 14.3 71.0 108.6 105.3 0.2 39.8 31.9 268.3 38.4 0.8 78.9 55.2 55.7 0.5 0.9 33.2 25.9 37.6 4.0 43.9 83.5 126.1 HP ENSG00000257017 Haptoglobin P00738 16 72054505-72061055 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Immunity" "Antibiotic, Antimicrobial, Antioxidant, Serine protease homolog" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 91 "liver: 61113.6" "Cell type enriched" "Detected in many" 43 "Hepatocytes: 59512.7" "Cancer enriched" "Detected in many" 81 "liver cancer: 1297.4" "Region enhanced" "Detected in all" "medulla oblongata: 29.7" "Group enriched" "Detected in many" 5 "classical monocyte: 49.3;eosinophil: 80.2" "Group enriched" "Detected in many" 7 "granulocytes: 80.2;monocytes: 49.3" "Group enriched" "Detected in some" 5 "Hep G2: 232.2;HSkMC: 121.4" "CAB003787, HPA047750, HPA066795" Enhanced Approved Vesicles "Secreted to blood" NA NA 998000000000 100000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB003787: , HPA047750: AB_2680146, HPA066795: " "unprognostic (6.38e-3)" "unprognostic (7.73e-3)" "unprognostic (1.23e-1)" "unprognostic (2.41e-2)" "unprognostic (2.34e-3)" "unprognostic (2.07e-1)" "unprognostic (7.79e-3)" "unprognostic (1.37e-1)" "unprognostic (2.31e-1)" "unprognostic (1.84e-1)" "unprognostic (6.30e-2)" "unprognostic (8.18e-2)" "prognostic unfavorable (6.94e-13)" "unprognostic (4.34e-4)" "unprognostic (1.80e-1)" "unprognostic (6.61e-2)" "unprognostic (2.49e-2)" 673.1 11.4 1.3 26.9 1.7 231.5 34.2 1.4 2.9 71.9 3.6 3.6 1.5 3.5 2.9 5.3 74.6 1.3 146.7 1.4 1.4 19.8 61113.6 91.3 1.7 29.7 2.0 9.9 7.6 0.2 49.9 2.5 3.7 7.3 0.6 0.7 6.1 0.2 5.0 3.4 4.4 4.5 2.3 72.0 6.2 2.1 8.3 2.7 6.3 0.4 3.0 3.8 3.3 5.9 0.0 0.0 0.0 0.0 6.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 8.5 0.3 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 11.2 0.2 232.2 0.3 33.3 6.2 121.4 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 2.0 0.4 2.6 0.0 0.0 1.1 23.6 0.0 0.0 0.1 0.0 0.0 16.2 0.0 0.0 0.0 0.0 6.8 5.1 0.0 0.8 0.0 0.0 3.9 0.0 14.1 0.0 12.7 0.0 6.2 49.3 80.2 0.0 2.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 14.2 0.0 2.1 0.0 0.0 15.2 1.3 1.7 1.4 2.9 1.4 1.4 29.7 2.0 3.7 2.3 8.3 5.9 0.4 19.2 228.7 1.6 96.1 0.1 0.7 1.9 0.0 0.4 0.4 0.3 66.6 1085.2 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 56.7 0.0 1128.3 0.0 10.4 0.1 45.5 0.0 1.3 3.8 0.4 1038.7 59512.7 2.3 0.0 0.0 0.2 4.1 1381.4 0.0 0.5 10.2 7.8 1.8 0.0 0.3 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.8 0.0 1.5 7.5 0.2 0.0 2.6 1.8 0.0 0.0 0.1 0.3 0.1 90.3 0.0 0.3 0.1 HPD "4-HPPD, 4HPPD, GLOD3, PPD" ENSG00000158104 "4-hydroxyphenylpyruvate dioxygenase" P32754 12 121839527-121863596 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Dioxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 2530.4" "Group enriched" "Detected in some" 9 "Hepatocytes: 1373.6;Proximal tubular cells: 2144.0" "Cancer enriched" "Detected in many" 100 "liver cancer: 540.9" "Region enhanced" "Detected in many" "hippocampal formation: 7.8" "Immune cell enhanced" "Detected in some" "eosinophil: 7.8" "Group enriched" "Detected in many" 4 "dendritic cells: 3.8;granulocytes: 7.8" "Cell line enriched" "Detected in some" 31 "Hep G2: 516.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038321, HPA038322" Enhanced Uncertain "Nuclear speckles" NA NA 26000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA038321: AB_2675957, HPA038322: AB_10670778" "unprognostic (3.01e-2)" "unprognostic (2.30e-1)" "unprognostic (4.81e-3)" "unprognostic (1.42e-3)" "unprognostic (1.10e-2)" "unprognostic (9.08e-2)" "unprognostic (1.13e-2)" "unprognostic (8.84e-2)" "unprognostic (5.58e-2)" "unprognostic (6.14e-3)" "unprognostic (9.72e-3)" "unprognostic (8.61e-3)" "unprognostic (7.16e-2)" "unprognostic (1.97e-1)" "unprognostic (4.12e-1)" "unprognostic (3.06e-2)" "unprognostic (2.34e-1)" 2.3 5.3 0.6 0.7 0.4 0.9 4.6 3.2 0.6 2.0 119.0 1.2 0.1 4.1 0.7 0.7 6.4 1.1 3.5 7.8 0.5 531.0 2530.4 2.0 0.3 1.5 1.0 4.7 3.9 0.1 1.1 0.3 0.8 2.3 0.5 0.3 0.2 7.3 2.2 0.2 0.9 1.4 0.6 2.3 1.9 10.2 3.5 0.1 0.7 0.1 0.1 3.7 1.9 1.0 0.3 0.9 0.6 0.6 0.3 0.6 0.6 0.0 0.1 0.0 0.0 0.2 0.5 0.2 0.6 1.1 0.2 0.4 0.2 0.0 0.0 0.3 0.8 1.2 5.4 516.4 11.5 1.8 16.4 3.6 0.3 0.0 0.0 1.3 0.0 0.5 0.8 0.0 1.3 1.3 0.2 0.4 9.9 0.4 0.0 0.3 1.6 0.5 0.0 1.4 0.1 0.1 1.5 0.1 0.1 6.9 1.1 0.9 0.2 0.0 0.3 0.1 0.1 0.8 0.6 0.7 0.2 1.2 0.0 0.0 0.6 7.8 0.0 0.8 0.0 0.1 0.1 0.1 1.0 0.1 0.2 0.2 3.9 0.0 1.3 3.8 0.0 0.3 0.6 0.4 3.2 0.6 7.8 0.5 1.5 1.0 0.8 0.6 3.5 1.0 0.0 0.0 0.0 0.7 15.8 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.3 55.8 0.0 92.0 0.0 0.8 0.0 0.0 193.7 0.5 38.0 0.1 0.0 2.6 0.0 80.2 1.0 16.2 0.3 0.4 0.0 0.1 0.0 0.0 38.9 1373.6 0.3 0.0 1.0 0.0 0.0 37.8 0.3 121.0 2.5 10.8 0.0 0.0 0.4 0.0 0.0 1.5 0.7 0.2 0.0 5.3 0.0 0.0 0.0 2144.0 0.0 0.0 0.0 2.0 0.2 1.8 1.4 0.0 0.0 1.1 8.0 7.1 0.0 0.0 HPGD SDR36C1 ENSG00000164120 "15-hydroxyprostaglandin dehydrogenase" P15428 4 174490175-174523154 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Prostaglandin metabolism" Oxidoreductase "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 235.0;urinary bladder: 376.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 457.8;Extravillous trophoblasts: 701.7;granulocytes: 864.5;Proximal enterocytes: 500.6;Urothelial cells: 922.8" "Cancer enhanced" "Detected in many" "urothelial cancer: 52.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 123.7;T-reg: 45.0" "Group enriched" "Detected in many" 73 "granulocytes: 123.7;T-cells: 45.0" "Cell line enhanced" "Detected in many" "A549: 157.8;ASC diff: 110.6;HEL: 355.0;OE19: 102.1;RT4: 565.7;SuSa: 121.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004919, HPA005679" Enhanced Supported Nucleoplasm,Cytosol No NA 20000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Nucleoplasm "HPA004919: AB_1079081, HPA005679: AB_1079080" "unprognostic (1.23e-3)" "unprognostic (1.61e-1)" "unprognostic (5.96e-2)" "unprognostic (1.25e-1)" "unprognostic (1.09e-2)" "unprognostic (2.53e-2)" "unprognostic (1.27e-1)" "unprognostic (2.23e-1)" "unprognostic (1.08e-1)" "unprognostic (4.28e-2)" "unprognostic (3.54e-3)" "unprognostic (2.34e-2)" "prognostic favorable (3.20e-4)" "unprognostic (2.44e-1)" "unprognostic (2.59e-1)" "unprognostic (1.37e-4)" "unprognostic (2.33e-2)" 9.2 16.5 1.0 11.4 0.7 2.7 159.9 0.5 1.2 32.2 8.7 60.9 152.2 45.5 36.5 81.6 13.4 24.9 1.6 1.2 2.8 60.2 210.8 91.0 5.5 1.4 2.0 1.1 2.6 85.3 2.1 99.1 1.0 10.2 57.4 1.0 7.7 4.0 2.5 39.8 117.3 63.7 0.8 10.3 235.0 1.6 2.2 12.2 1.7 3.0 26.6 376.0 83.0 0.7 0.0 157.8 0.0 0.0 110.6 5.4 0.4 0.0 0.0 0.0 0.4 45.1 0.2 0.1 0.0 0.0 0.2 14.2 16.0 0.0 0.0 0.3 2.9 355.0 10.8 0.3 0.0 2.1 0.9 5.6 2.6 0.0 0.1 0.1 0.0 22.6 0.2 0.0 0.0 0.3 1.2 0.3 1.4 102.1 7.4 16.3 0.3 1.3 36.2 565.7 0.9 0.4 0.0 1.3 3.5 121.3 0.1 0.0 0.3 0.0 0.2 0.1 0.0 28.4 0.0 0.1 0.3 0.2 0.0 123.7 0.3 16.6 9.9 0.0 15.6 0.4 5.2 4.5 0.7 0.2 1.6 4.0 1.3 1.1 0.0 0.0 45.0 3.0 1.0 0.7 0.5 1.2 1.2 2.8 1.4 2.0 1.0 0.8 2.2 0.7 3.4 16.0 33.0 0.0 4.3 17.3 80.8 6.9 45.5 3.3 14.5 6.7 0.8 35.8 23.6 22.0 0.0 48.5 38.5 457.8 21.5 7.4 1.4 5.7 5.4 18.2 8.4 17.2 0.8 94.5 701.7 25.3 196.7 36.4 864.5 1.5 13.9 245.7 21.4 0.0 9.7 60.7 0.0 14.8 19.5 0.5 19.9 29.2 76.5 5.6 2.9 0.0 10.3 0.0 4.1 42.4 254.7 0.0 50.2 76.8 500.6 131.1 4.4 0.8 0.0 2.4 3.7 0.5 1.0 53.4 22.4 56.6 42.7 65.0 58.9 922.8 HPX ENSG00000110169 Hemopexin P02790 11 6431049-6442617 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Host-virus interaction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 908 "liver: 5440.6" "Cell type enriched" "Detected in some" 38 "Hepatocytes: 6095.8" "Cancer enriched" "Detected in many" 79 "liver cancer: 571.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "Hep G2: 21.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016725, HPA065318, HPA068847" Approved "Secreted to blood" NA NA 425000000000 190000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB016725: , HPA065318: , HPA068847: " "unprognostic (3.39e-2)" "unprognostic (9.26e-2)" "unprognostic (3.88e-1)" "unprognostic (6.19e-4)" "unprognostic (2.05e-2)" "unprognostic (2.41e-1)" "prognostic favorable (2.26e-4)" "unprognostic (6.33e-2)" "unprognostic (5.67e-3)" "unprognostic (3.88e-1)" "unprognostic (5.08e-3)" "unprognostic (2.78e-2)" "unprognostic (5.82e-12)" "unprognostic (2.01e-1)" "unprognostic (4.48e-1)" "unprognostic (1.84e-2)" "unprognostic (2.14e-2)" 1.1 0.8 0.8 0.1 0.7 0.1 5.9 1.0 1.0 1.6 0.6 1.2 0.4 1.0 0.2 0.5 1.6 0.3 0.9 0.7 0.7 1.4 5440.6 1.2 0.3 0.7 0.7 1.6 5.5 0.1 1.2 0.3 0.7 2.4 0.6 1.7 1.1 0.6 0.3 1.6 1.1 0.3 0.6 3.8 0.9 1.1 0.8 0.1 0.9 0.0 0.1 1.1 1.2 0.7 0.2 0.1 0.4 0.2 0.0 0.6 0.0 0.0 0.1 0.1 0.3 1.3 0.0 0.8 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.2 0.2 0.6 0.2 21.3 0.0 3.0 0.0 0.8 0.6 0.1 0.0 0.5 0.1 0.2 0.4 0.1 0.1 0.4 0.0 0.0 0.3 0.9 0.0 0.1 1.3 0.2 0.0 0.1 0.2 0.0 1.0 3.0 0.2 0.2 1.1 0.0 0.5 0.3 0.2 1.0 0.1 0.4 0.2 0.9 0.2 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 1.0 1.0 0.7 0.7 0.7 0.7 0.7 0.6 0.8 0.7 0.5 3.2 0.5 0.3 15.1 0.6 0.2 0.2 0.0 1.5 19.1 7.7 0.7 80.1 0.2 0.0 2.1 0.1 0.1 0.6 0.0 0.1 2.3 0.2 0.3 6.2 0.0 157.7 0.7 0.6 0.1 0.4 0.0 1.2 0.0 1.1 132.8 6095.8 0.2 0.0 0.8 0.7 0.0 155.3 0.2 2.9 0.3 0.2 0.0 1.0 0.0 0.2 0.0 0.0 0.1 0.8 0.0 0.0 0.0 1.7 0.2 0.0 1.0 2.1 0.0 0.4 0.5 0.6 0.5 0.0 0.3 0.0 11.3 0.2 0.5 0.3 HRC MGC133236 ENSG00000130528 "Histidine rich calcium binding protein" P23327 19 49151198-49155396 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 50 "heart muscle: 718.3;skeletal muscle: 453.0;tongue: 244.7" "Cell type enriched" "Detected in some" 17 "Cardiomyocytes: 1182.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Hep G2: 5.8;HSkMC: 5.6;K-562: 8.0;THP-1: 13.9;U-266/84: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA004833 Enhanced "Intracellular and membrane" NA NA 100000 "Cluster 38: Heart - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA004833: AB_1079083" "unprognostic (1.06e-1)" "unprognostic (1.04e-3)" "unprognostic (1.46e-2)" "unprognostic (4.94e-2)" "unprognostic (5.66e-2)" "unprognostic (9.75e-3)" "unprognostic (3.44e-1)" "unprognostic (1.74e-1)" "unprognostic (4.09e-1)" "unprognostic (1.62e-1)" "unprognostic (7.41e-3)" "unprognostic (5.85e-3)" "unprognostic (4.04e-2)" "unprognostic (6.68e-2)" "unprognostic (1.07e-1)" "unprognostic (1.86e-1)" "unprognostic (1.46e-1)" 9.3 3.6 2.5 0.6 2.7 0.0 5.7 3.1 4.0 6.4 2.0 2.4 0.9 6.3 5.4 4.5 9.2 2.2 718.3 2.5 2.3 3.5 1.9 2.8 0.8 2.4 2.6 4.6 1.3 1.5 1.5 2.1 2.6 4.3 0.9 0.8 8.1 2.5 453.0 2.9 2.3 2.1 2.2 0.5 1.8 1.4 2.8 0.6 4.7 244.7 0.4 3.1 3.9 2.4 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.6 5.8 0.0 0.0 1.1 5.6 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 13.9 0.2 0.0 0.0 0.3 0.0 0.0 4.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.7 3.1 4.0 2.5 2.3 2.4 2.6 2.6 2.2 2.8 2.4 3.7 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.0 1.0 0.8 1.0 1182.5 0.0 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.3 1.7 11.0 1.2 0.0 0.0 0.2 0.0 20.9 0.0 0.5 0.0 0.0 0.7 0.6 0.1 3.3 0.1 2.8 0.0 0.0 1.1 0.4 8.4 0.3 3.6 0.0 0.0 1.3 0.0 0.0 0.1 0.1 0.4 8.2 0.1 0.2 0.5 0.0 0.0 0.2 65.7 8.7 44.2 0.0 0.2 0.1 0.1 0.1 0.2 2.8 1.5 0.2 HSD17B4 "DBP, MFE-2, SDR8C1" ENSG00000133835 "Hydroxysteroid 17-beta dehydrogenase 4" P51659 5 119452473-119637199 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Oxidoreductase" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 320.0" "Cell type enhanced" "Detected in all" "Hepatocytes: 225.1;Oligodendrocytes: 221.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 75.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021302, HPA021311, HPA021479" Enhanced Enhanced Peroxisomes NA NA 450000 "Cluster 2: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Peroxisomes "HPA021302: AB_1844350, HPA021311: AB_1844351, HPA021479: AB_1844352" "unprognostic (1.03e-1)" "unprognostic (1.05e-1)" "prognostic favorable (1.33e-4)" "unprognostic (3.21e-2)" "unprognostic (1.24e-2)" "unprognostic (3.12e-2)" "unprognostic (2.83e-3)" "unprognostic (5.47e-2)" "unprognostic (1.54e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (3.85e-1)" "prognostic favorable (6.31e-6)" "unprognostic (1.60e-1)" "unprognostic (8.26e-2)" "unprognostic (1.80e-1)" "unprognostic (6.65e-3)" 74.4 85.0 37.2 41.9 50.2 19.7 44.4 51.1 50.0 68.8 47.2 64.5 79.3 34.1 53.0 50.9 39.1 52.5 68.6 34.9 50.7 84.4 320.0 75.6 33.2 50.6 49.5 34.8 55.2 75.5 26.5 53.4 49.2 56.8 65.9 27.2 44.9 79.0 59.8 51.8 87.6 39.5 44.7 36.6 53.8 20.9 49.9 31.9 133.9 52.8 39.7 57.7 31.5 56.3 68.8 59.8 104.1 143.7 261.8 120.3 57.9 63.4 80.3 57.3 103.0 49.4 112.8 84.4 128.0 70.6 81.0 68.7 77.0 144.4 84.3 94.6 79.8 118.1 62.0 96.9 65.8 38.0 169.9 110.0 56.3 64.9 54.7 69.3 103.9 59.4 41.0 48.9 64.2 64.0 59.2 23.6 82.1 161.1 43.1 68.7 103.0 104.8 92.2 192.7 81.1 70.6 149.0 23.4 78.7 93.3 88.7 68.2 67.6 52.7 38.1 66.5 53.1 26.3 55.3 32.6 63.7 104.4 56.7 75.5 27.3 49.9 6.5 15.5 7.3 11.1 5.8 5.3 21.3 10.3 5.5 5.2 4.9 6.9 17.1 13.8 4.1 12.2 37.2 50.2 51.1 50.0 34.9 50.7 50.6 49.5 49.2 44.7 49.9 56.3 38.9 73.7 125.2 47.3 28.2 14.9 42.5 43.2 24.5 19.7 31.1 22.1 76.4 64.3 52.3 36.8 14.6 64.3 19.1 40.0 84.1 39.9 8.8 29.0 48.9 32.3 33.0 42.1 92.9 35.8 29.3 35.6 48.4 35.8 68.4 25.3 32.2 225.1 77.9 15.2 102.8 45.8 22.4 51.8 13.8 13.4 34.5 46.7 8.8 49.6 85.7 47.3 9.2 78.4 221.5 20.5 29.6 51.1 23.1 24.8 85.7 65.4 33.8 18.6 6.6 29.2 32.2 30.6 22.7 34.7 17.2 65.0 15.7 57.2 55.3 39.7 HSD17B6 "HSE, RODH, SDR9C6" ENSG00000025423 "Hydroxysteroid 17-beta dehydrogenase 6" O14756 12 56752161-56787790 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "liver: 1804.3" "Cell type enriched" "Detected in many" 11 "Hepatocytes: 1969.3" "Cancer enriched" "Detected in many" 5 "liver cancer: 170.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Karpas-707: 13.4;U-266/84: 18.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059141 Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 16: U-266 - Nucleosome" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Vesicles" "HPA059141: AB_2683922" "unprognostic (7.70e-2)" "unprognostic (8.76e-2)" "unprognostic (5.08e-2)" "unprognostic (1.92e-2)" "unprognostic (2.01e-1)" "unprognostic (3.79e-2)" "prognostic favorable (6.32e-4)" "unprognostic (1.06e-2)" "unprognostic (3.21e-1)" "unprognostic (1.44e-1)" "unprognostic (1.35e-1)" "unprognostic (6.74e-2)" "unprognostic (2.50e-10)" "unprognostic (1.26e-1)" "unprognostic (1.79e-1)" "unprognostic (1.08e-1)" "unprognostic (1.05e-1)" 8.5 2.5 13.1 6.9 16.2 0.5 0.7 13.4 18.9 28.0 9.4 24.7 3.2 20.9 1.6 9.9 6.5 9.1 0.8 12.3 12.6 2.5 1804.3 63.2 0.8 12.0 14.6 6.0 0.6 0.5 0.6 5.4 11.5 51.2 7.6 0.8 0.4 69.2 0.4 1.2 4.8 13.1 12.4 47.5 5.7 23.3 13.7 0.9 31.4 0.5 0.9 36.7 14.6 12.8 0.3 0.8 1.9 0.4 1.9 1.4 2.3 4.1 3.5 1.9 1.9 0.4 0.4 12.0 1.7 0.5 0.5 0.3 6.1 1.1 1.1 7.7 2.2 3.7 1.2 0.6 1.2 1.9 6.0 1.0 0.4 1.2 0.6 0.6 0.0 10.3 1.1 13.4 0.9 2.4 5.6 1.3 7.5 0.7 0.7 7.4 0.8 2.9 0.2 1.4 11.0 2.3 2.0 3.6 0.9 0.7 0.6 1.5 0.3 0.9 0.8 4.0 1.0 11.7 18.0 7.8 1.3 6.9 0.6 0.0 0.0 0.0 1.0 0.2 1.2 0.7 0.8 0.8 0.2 0.3 1.1 0.7 0.0 0.0 0.5 0.7 1.0 0.3 13.1 16.2 13.4 18.9 12.3 12.6 12.0 14.6 11.5 12.4 13.7 12.8 0.4 173.1 130.6 21.2 6.1 1.3 3.1 0.6 0.6 0.4 0.7 0.6 0.2 27.1 9.3 0.0 0.0 1.4 0.4 0.0 0.0 0.1 4.6 0.7 3.5 1.3 0.0 29.5 1.4 0.0 2.6 5.0 0.0 0.1 0.0 1.6 26.0 1969.3 0.4 0.0 2.1 0.4 0.0 40.2 0.3 4.5 12.5 0.5 0.0 1.0 1.0 1.3 0.0 3.0 5.5 0.1 0.0 1.5 0.8 16.1 0.0 0.3 1.5 0.6 13.1 0.6 3.5 16.4 11.4 1.2 1.6 0.4 2.2 36.0 0.7 1.1 HSDL2 "C9orf99, SDR13C1" ENSG00000119471 "Hydroxysteroid dehydrogenase like 2" Q6YN16 9 112380080-112472405 "Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 181.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 214.8;Early spermatids: 153.9;Granulosa cells: 187.2;Late spermatids: 163.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 5 "granulocytes: 54.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042890, HPA050453" Enhanced Enhanced Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA042890: AB_2678216, HPA050453: AB_2681131" "unprognostic (3.17e-3)" "unprognostic (1.62e-2)" "unprognostic (1.90e-3)" "prognostic favorable (9.23e-6)" "unprognostic (3.94e-2)" "unprognostic (1.43e-2)" "unprognostic (1.17e-1)" "unprognostic (5.15e-2)" "unprognostic (7.58e-2)" "unprognostic (6.48e-2)" "unprognostic (1.57e-1)" "unprognostic (1.82e-1)" "prognostic favorable (9.29e-7)" "unprognostic (1.44e-1)" "unprognostic (2.33e-1)" "unprognostic (1.35e-2)" "unprognostic (7.35e-2)" 76.3 63.6 28.1 13.3 30.1 11.6 22.8 25.1 29.5 23.3 27.6 31.7 38.9 22.8 11.5 29.8 21.2 19.0 89.9 24.8 33.1 69.0 149.0 28.7 13.9 25.4 33.2 50.8 20.0 21.8 8.8 16.8 27.1 20.3 26.9 12.6 18.8 15.9 151.7 31.1 32.2 20.5 26.6 18.6 24.6 14.0 32.0 19.6 30.4 181.3 15.8 29.2 15.0 28.5 45.0 39.4 29.0 14.8 49.0 48.4 33.4 30.1 18.6 21.1 17.7 77.0 49.4 28.5 16.2 44.4 26.9 50.6 31.9 42.2 25.8 120.9 21.0 30.0 58.5 76.1 30.7 17.1 18.5 52.0 29.9 31.3 22.8 30.5 24.8 34.7 42.3 18.9 58.2 29.6 42.5 15.3 17.2 106.9 50.3 27.1 87.4 42.7 44.5 40.4 20.7 14.5 75.8 49.5 26.0 23.7 70.0 20.0 28.3 30.2 27.9 85.2 29.6 21.5 57.3 13.5 37.0 24.8 18.2 54.3 8.4 32.8 4.6 8.1 6.8 6.9 4.8 5.0 9.5 8.4 5.6 5.9 48.0 5.9 11.5 9.4 8.7 4.9 28.1 30.1 25.1 29.5 24.8 33.1 25.4 33.2 27.1 26.6 32.0 28.5 32.0 99.3 84.3 48.6 14.1 13.3 17.5 21.6 29.6 9.3 12.0 13.3 214.8 14.3 32.2 14.7 6.2 26.5 18.3 23.7 64.6 15.5 153.9 38.6 38.3 19.1 14.9 32.8 10.8 18.7 30.9 31.1 29.0 27.8 30.4 187.2 17.2 124.2 35.7 6.7 12.2 32.2 8.2 23.6 12.5 163.0 27.4 27.5 8.8 15.9 47.3 24.1 6.2 16.1 19.3 13.2 23.5 47.0 20.9 16.0 52.4 111.1 37.7 14.5 46.0 18.1 46.9 12.9 16.4 34.2 16.2 31.7 16.2 108.9 36.2 29.5 HSPA12B "C20orf60, dJ1009E24.2" ENSG00000132622 "Heat shock protein family A (Hsp70) member 12B" Q96MM6 20 3732685-3753111 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 65.0;Endothelial cells: 50.1;Hepatic stellate cells: 16.1;Late spermatids: 16.8;Microglial cells: 15.0;Peritubular cells: 15.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 4.9;EFO-21: 4.9;HUVEC TERT2: 9.5;TIME: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013659, HPA015639" Uncertain Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA013659: AB_1234541, HPA015639: AB_1851192" "unprognostic (1.00e-1)" "unprognostic (1.14e-1)" "unprognostic (1.30e-1)" "unprognostic (6.99e-2)" "unprognostic (4.53e-2)" "unprognostic (2.09e-1)" "unprognostic (1.21e-1)" "unprognostic (6.40e-2)" "unprognostic (1.57e-1)" "unprognostic (1.07e-2)" "unprognostic (6.45e-2)" "unprognostic (8.74e-2)" "unprognostic (2.61e-2)" "unprognostic (1.75e-2)" "unprognostic (1.47e-1)" "unprognostic (4.05e-1)" "unprognostic (1.66e-2)" 23.1 4.1 9.3 3.0 8.9 1.3 23.0 6.6 7.8 15.0 4.2 6.6 1.8 12.5 1.2 4.2 10.3 4.7 29.3 6.6 7.0 11.8 1.7 20.6 1.7 8.2 7.9 8.2 2.6 1.5 2.9 11.3 8.4 4.9 1.2 0.4 5.4 1.9 12.3 7.7 6.1 4.0 6.8 25.3 5.1 5.2 10.4 0.7 9.2 10.2 0.9 10.2 10.2 6.0 0.5 1.7 0.7 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 4.9 0.1 0.2 4.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.1 0.0 2.6 0.1 0.1 0.0 0.1 0.0 0.1 0.0 1.4 9.5 0.4 0.3 0.2 0.0 1.0 0.4 0.9 1.0 0.0 0.8 1.8 0.2 0.5 0.0 0.0 0.9 0.7 0.3 0.2 0.1 0.1 0.2 0.5 5.3 0.1 2.2 0.7 0.4 0.4 0.3 0.5 0.1 0.8 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 9.3 8.9 6.6 7.8 6.6 7.0 8.2 7.9 8.4 6.8 10.4 6.0 65.0 0.0 0.0 0.3 0.4 1.9 0.1 0.0 0.0 0.5 0.7 0.3 5.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 9.8 0.2 3.2 50.1 0.0 0.0 0.5 0.0 0.2 10.5 0.0 0.1 0.0 0.1 16.1 0.3 0.5 0.0 0.4 0.0 0.0 1.4 2.5 16.8 7.5 0.2 0.0 15.0 0.0 3.1 0.0 0.0 0.3 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 1.2 2.0 3.5 1.7 0.3 1.1 0.4 0.3 0.7 0.0 0.2 IDO2 INDOL1 ENSG00000188676 "Indoleamine 2,3-dioxygenase 2" Q6ZQW0 8 39934614-40016391 "Metabolic proteins, Predicted intracellular proteins" "Immunity, Tryptophan catabolism" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "liver: 5.4;placenta: 4.0" "Cell type enhanced" "Detected in some" "Early spermatids: 21.0;Endometrial ciliated cells: 18.4;Glandular and luminal cells: 51.3;Late spermatids: 6.9;monocytes: 14.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054911 Approved Cytosol NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 44: Endometrium - Transcription" Cytosol "HPA054911: " "unprognostic (2.00e-3)" "unprognostic (2.34e-5)" "unprognostic (2.22e-3)" "unprognostic (4.41e-3)" "unprognostic (5.37e-2)" "unprognostic (3.69e-5)" "unprognostic (1.19e-1)" "unprognostic (4.73e-3)" "unprognostic (1.20e-2)" "unprognostic (2.78e-1)" "unprognostic (4.11e-3)" "unprognostic (2.25e-1)" "unprognostic (6.47e-7)" "unprognostic (3.25e-2)" "unprognostic (1.96e-3)" "unprognostic (3.35e-2)" "unprognostic (3.08e-3)" 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 5.4 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.1 21.0 18.4 4.4 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 51.3 0.0 0.0 0.0 2.6 0.2 0.0 0.4 0.0 0.0 0.0 1.9 6.9 0.3 0.8 0.0 0.0 14.6 0.0 0.0 0.5 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.1 0.1 0.4 0.2 0.0 0.3 0.0 0.4 0.0 0.0 0.1 IFIT1 "G10P1, GARG-16, IFI56, IFNAI1" ENSG00000185745 "Interferon induced protein with tetratricopeptide repeats 1" P09914 10 89392546-89406487 "Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 63.3;Distal tubular cells: 64.6;Muller glia cells: 77.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 66.7" "Group enriched" "Detected in all" 8 "granulocytes: 66.7;monocytes: 21.7" "Group enriched" "Detected in many" 5 "BJ hTERT+ SV40 Large T+: 325.3;BJ hTERT+ SV40 Large T+ RasG12V: 318.1" "CAB045980, HPA053890, HPA055380" Approved Enhanced Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB045980: AB_11125836, HPA053890: , HPA055380: AB_2682800" "unprognostic (1.16e-1)" "unprognostic (2.77e-1)" "unprognostic (1.80e-1)" "unprognostic (7.96e-3)" "unprognostic (1.35e-3)" "unprognostic (2.02e-2)" "unprognostic (6.45e-2)" "unprognostic (3.66e-1)" "unprognostic (3.34e-1)" "unprognostic (8.65e-3)" "unprognostic (1.82e-2)" "unprognostic (7.68e-2)" "unprognostic (2.21e-2)" "unprognostic (2.03e-2)" "unprognostic (5.95e-2)" "unprognostic (9.75e-3)" "unprognostic (6.40e-3)" 17.5 38.0 12.6 4.5 12.4 9.9 14.3 15.2 17.8 17.2 13.0 14.6 3.9 6.9 6.6 5.0 9.5 13.8 22.7 12.4 12.7 23.7 24.9 14.1 3.4 15.1 14.2 9.1 6.1 11.9 20.3 9.9 13.5 6.7 5.0 8.0 42.0 6.2 17.4 4.9 7.5 7.9 29.4 18.7 6.9 5.4 13.9 13.3 9.1 20.6 2.4 7.6 9.4 14.4 10.0 1.2 2.6 17.2 8.1 16.5 0.2 11.7 68.9 325.3 318.1 1.0 10.4 0.7 3.8 14.6 63.4 8.2 1.0 1.0 15.6 0.6 1.1 1.7 8.4 0.9 9.2 1.4 1.7 13.5 0.3 6.2 0.1 6.4 0.4 1.7 0.2 7.7 3.5 0.3 2.3 6.8 0.3 0.1 6.3 3.1 0.8 2.0 7.9 1.2 0.1 0.6 3.1 2.4 69.6 2.4 1.3 1.5 0.5 1.7 1.9 2.5 1.4 1.0 1.3 0.6 2.2 2.3 0.9 9.9 12.6 15.4 1.6 15.6 2.9 3.0 4.1 2.9 3.7 3.2 5.7 3.5 66.7 1.9 21.7 0.2 4.9 6.6 12.6 12.4 15.2 17.8 12.4 12.7 15.1 14.2 13.5 29.4 13.9 14.4 63.3 35.3 5.8 7.2 2.5 2.9 3.3 12.9 3.4 26.4 2.4 5.2 19.1 4.3 7.6 9.2 18.8 4.8 4.7 6.3 64.6 12.6 0.4 21.1 3.2 41.4 0.0 4.0 13.8 5.1 20.8 22.8 0.5 7.2 2.5 11.0 9.3 12.1 36.9 32.0 13.3 1.4 4.1 14.5 3.3 3.0 19.3 13.3 1.8 16.9 13.5 77.9 1.0 12.1 14.4 3.6 4.7 43.6 0.7 1.1 9.8 26.7 17.8 13.4 39.5 18.1 11.4 0.5 3.0 1.0 1.7 1.4 3.1 15.4 0.2 1.2 IFT46 "C11orf2, C11orf60, CFAP32, FLJ21827" ENSG00000118096 "Intraflagellar transport 46" Q9NQC8 11 118544528-118572970 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 64.9;Respiratory ciliated cells: 84.3;Spermatocytes: 44.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037909, HPA057550" Approved Approved "Actin filaments" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" "Actin filaments" "HPA037909: AB_10672731, HPA057550: AB_2683464" "unprognostic (8.77e-2)" "unprognostic (1.22e-1)" "unprognostic (2.79e-1)" "unprognostic (2.35e-3)" "unprognostic (6.76e-2)" "unprognostic (1.55e-2)" "unprognostic (1.07e-1)" "unprognostic (3.29e-2)" "unprognostic (3.75e-3)" "unprognostic (1.47e-1)" "unprognostic (1.37e-1)" "unprognostic (3.61e-1)" "unprognostic (9.02e-3)" "unprognostic (1.42e-1)" "unprognostic (2.48e-1)" "unprognostic (6.53e-2)" "unprognostic (2.41e-1)" 14.7 19.4 29.0 8.8 29.7 5.6 26.8 33.9 35.8 23.1 37.3 18.6 7.7 19.4 24.8 13.7 66.8 16.4 21.3 28.5 32.5 26.9 17.0 15.1 11.0 32.1 37.2 27.2 16.7 18.4 28.9 8.7 31.8 20.9 11.1 35.7 15.9 20.2 17.9 13.5 10.3 20.7 31.5 11.8 15.0 28.1 31.4 16.0 27.5 17.6 12.8 16.0 16.7 32.1 15.6 18.4 26.1 16.9 42.8 35.7 3.2 31.9 46.2 29.3 27.6 22.5 28.8 23.8 46.1 38.6 7.2 22.1 26.7 31.8 34.4 9.1 21.8 49.2 9.0 8.6 32.0 11.8 13.8 32.4 37.0 49.0 46.2 26.6 28.9 32.1 27.4 16.0 37.3 71.7 31.3 15.6 7.7 27.3 38.0 25.6 20.0 19.0 23.5 21.4 16.7 18.3 23.2 29.9 20.1 15.0 46.2 16.7 24.6 31.6 20.2 18.4 12.0 9.9 14.3 26.7 16.0 21.2 23.2 2.8 5.2 5.9 8.6 4.3 9.9 11.1 7.6 7.9 6.9 8.3 9.2 5.5 1.6 11.0 4.2 7.0 9.9 4.8 29.0 29.7 33.9 35.8 28.5 32.5 32.1 37.2 31.8 31.5 31.4 32.1 5.5 9.6 10.3 10.4 4.9 4.0 8.3 14.4 8.0 12.5 11.6 8.4 14.5 10.0 15.4 11.0 18.8 5.3 3.8 1.6 5.9 17.1 20.5 64.9 11.7 9.3 4.2 6.6 8.7 11.6 7.1 9.5 4.1 9.6 12.0 10.2 8.6 5.9 8.8 1.7 8.9 4.3 14.2 2.4 3.5 15.7 10.2 3.1 1.8 5.6 5.5 14.8 2.1 4.0 6.4 10.2 4.2 18.4 6.1 6.1 3.4 14.3 84.3 16.5 0.0 11.3 11.5 44.9 38.4 6.5 7.0 1.9 4.2 9.8 5.3 3.9 IGHA2 ENSG00000211890 "Immunoglobulin heavy constant alpha 2 (A2m marker)" P01877 14 105583731-105588395 "Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 5017.7;salivary gland: 3728.4" "Group enriched" "Detected in many" 22 "B-cells: 3713.4;Plasma cells: 10918.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 876 "memory B-cell: 279.6;naive B-cell: 123.8" "Lineage enriched" "Detected in single" 1214 "B-cells: 279.6" "Group enriched" "Detected in some" 42 "U-266/70: 181.9;U-266/84: 63.9" "Not detected" "Not detected" "HPA001217, HPA006013" Approved "Immunoglobulin genes" NA NA 67000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001217: AB_1079120, HPA006013: AB_1079119" "prognostic favorable (1.98e-9)" "unprognostic (3.20e-2)" "unprognostic (2.23e-2)" "unprognostic (1.53e-2)" "unprognostic (1.93e-2)" "prognostic favorable (8.40e-5)" "unprognostic (4.56e-2)" "unprognostic (2.59e-1)" "unprognostic (3.17e-1)" "unprognostic (3.69e-2)" "unprognostic (1.20e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (7.50e-6)" "unprognostic (2.12e-1)" "unprognostic (3.28e-2)" "unprognostic (9.70e-2)" "unprognostic (4.47e-1)" 24.3 3.7 0.0 14.2 0.0 12.4 329.7 0.0 0.0 47.6 0.0 5017.7 15.3 8.9 0.0 219.7 35.0 0.9 4.8 0.0 0.0 49.7 35.1 134.2 6.8 0.0 0.0 5.3 30.3 0.0 4.9 0.3 0.0 37.7 8.8 0.0 3728.4 0.1 2.1 17.8 2261.3 1.0 0.0 700.9 670.1 1.1 0.0 22.4 59.8 0.0 13.0 93.4 67.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.8 0.0 0.0 2.8 2.8 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.1 0.0 0.9 181.9 63.9 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 279.6 0.0 0.1 0.1 123.8 0.0 0.1 0.2 0.0 0.1 0.1 0.1 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.2 12.4 0.0 3713.4 0.0 2.4 0.0 2.8 0.0 1.4 0.3 1.2 5.7 0.6 0.0 0.0 0.1 3.2 3.7 0.0 0.0 0.0 0.0 0.0 15.6 8.5 56.2 0.0 0.0 0.0 8.0 10.7 0.0 15.2 0.0 78.9 6.0 0.3 0.0 0.0 2.9 0.0 10.8 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.0 10918.5 0.3 0.0 0.1 0.0 0.0 0.0 0.1 23.6 0.0 0.0 12.3 0.0 0.4 325.4 0.0 4.8 0.2 IGHG1 ENSG00000211896 "Immunoglobulin heavy constant gamma 1 (G1m marker)" P01857 14 105736343-105743071 "Disease related genes, FDA approved drug targets, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 11451.9;urinary bladder: 3998.0" "Group enriched" "Detected in many" 16 "B-cells: 3900.5;Plasma cells: 9883.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 12.7" "Immune cell enriched" "Detected in some" 6 "memory B-cell: 766.8" "Lineage enriched" "Detected in many" 123 "B-cells: 766.8" "Group enriched" "Detected in many" 9 "Karpas-707: 157.8;U-698: 392.7" "HPA001245, CAB008642" Supported "Immunoglobulin genes" NA NA 230000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB008642: AB_1617595, HPA001245: AB_1079121" "unprognostic (6.47e-3)" "unprognostic (4.39e-3)" "unprognostic (2.91e-2)" "unprognostic (2.32e-3)" "unprognostic (1.55e-2)" "prognostic favorable (2.67e-4)" "unprognostic (3.90e-2)" "unprognostic (3.25e-1)" "unprognostic (7.52e-2)" "unprognostic (5.36e-3)" "unprognostic (8.06e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.49e-9)" "unprognostic (3.12e-1)" "unprognostic (3.52e-1)" "unprognostic (8.96e-2)" "unprognostic (7.61e-2)" 526.0 696.8 0.7 1661.1 0.6 681.1 203.2 0.5 4.5 518.2 2.8 302.1 103.7 210.6 18.4 334.4 661.5 312.9 143.2 0.4 2.2 491.7 356.1 962.4 3281.1 4.7 3.2 407.0 38.5 7.9 35.8 2.3 2.3 209.8 85.1 0.3 391.6 250.8 13.1 28.5 1008.8 27.6 12.7 11451.9 608.9 172.8 1.2 1773.7 1277.9 0.1 5826.8 3998.0 267.2 1.8 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.7 0.0 0.0 2.3 0.0 0.0 0.0 8.4 0.0 5.3 0.0 0.0 0.0 22.6 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 157.8 0.0 0.0 1.7 2.1 2.6 0.0 0.0 2.9 15.1 3.7 0.0 0.0 18.2 17.0 3.1 0.0 0.0 0.0 0.0 0.2 10.8 0.0 3.2 3.3 4.5 4.9 0.3 392.7 0.1 3.7 0.0 0.2 0.3 0.1 0.3 0.0 0.2 766.8 0.6 0.3 0.4 134.9 0.0 0.1 6.2 0.1 0.1 0.1 0.2 96.2 0.7 0.6 0.5 4.5 0.4 2.2 4.7 3.2 2.3 12.7 1.2 1.8 2.9 73.7 378.5 0.0 3900.5 0.0 8.1 0.0 0.0 0.0 0.5 0.0 2.8 22.8 9.3 0.0 0.0 0.0 0.4 7.0 0.0 0.0 0.5 0.0 0.1 8.5 13.9 83.4 0.0 0.0 0.0 13.6 8.2 0.0 209.4 0.0 46.1 52.9 0.1 0.0 0.0 5.0 0.0 62.8 0.0 0.9 0.0 9.7 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 5.4 0.0 9883.3 9.1 0.0 10.9 1.5 0.1 0.0 0.0 1.5 1.9 1.0 0.0 0.0 0.0 415.6 0.0 13.6 0.1 IGHG2 ENSG00000211893 "Immunoglobulin heavy constant gamma 2 (G2m marker)" P01859 14 105639559-105644790 "FDA approved drug targets, Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "lymphoid tissue: 4319.4" "Group enriched" "Detected in some" 8 "B-cells: 2050.1;Plasma cells: 2918.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 447 "memory B-cell: 339.0;naive B-cell: 119.3" "Lineage enriched" "Detected in single" 661 "B-cells: 339.0" "Group enriched" "Detected in some" 4 "RH-30: 9.6;RPMI-8226: 25.1" HPA001245 Approved "Immunoglobulin genes" NA NA 250000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001245: AB_1079121" "prognostic favorable (3.53e-4)" "unprognostic (6.88e-3)" "unprognostic (2.40e-2)" "unprognostic (1.55e-2)" "unprognostic (2.40e-2)" "prognostic favorable (3.30e-6)" "unprognostic (1.06e-1)" "unprognostic (6.67e-2)" "unprognostic (1.74e-1)" "unprognostic (7.59e-2)" "unprognostic (1.80e-1)" "unprognostic (1.41e-1)" "prognostic unfavorable (4.30e-8)" "unprognostic (4.72e-2)" "unprognostic (3.32e-2)" "unprognostic (1.05e-1)" "unprognostic (7.40e-2)" 109.5 11.0 1.3 170.0 1.4 34.8 56.0 0.2 4.1 59.9 0.8 202.8 7.5 55.8 0.8 90.2 51.5 20.7 15.2 0.2 1.1 157.5 98.2 171.0 65.4 0.9 0.2 16.3 8.0 0.1 8.2 0.0 0.5 64.2 9.4 0.0 201.2 1.2 3.5 13.3 330.7 1.0 1.5 4319.4 87.2 2.3 0.3 16.7 134.4 0.0 226.0 100.4 104.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 25.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.4 339.0 0.5 0.0 0.3 119.3 0.0 0.0 0.3 0.0 0.0 0.1 0.0 34.5 1.3 1.4 0.2 4.1 0.2 1.1 0.9 0.2 0.5 1.5 0.3 1.8 0.2 54.5 305.3 0.0 2050.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.9 2.8 13.6 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.2 4.1 0.0 32.5 0.0 0.0 0.0 3.1 0.0 0.0 126.1 0.0 8.2 5.1 0.1 0.0 0.0 0.9 0.0 12.4 0.0 0.2 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 2918.6 0.7 0.0 3.5 0.0 0.0 0.0 0.3 0.9 0.1 0.0 0.0 0.0 0.1 305.5 0.0 0.7 0.0 IGHG3 ENSG00000211897 "Immunoglobulin heavy constant gamma 3 (G3m marker)" 14 105764503-105771405 "Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 1289.1" "Group enriched" "Detected in many" 7 "B-cells: 2548.4;Plasma cells: 4543.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 415 "memory B-cell: 211.0;naive B-cell: 64.4" "Lineage enriched" "Detected in single" 636 "B-cells: 211.0" "Group enriched" "Detected in some" 5 "HDLM-2: 23.8;Karpas-707: 18.7;U-698: 49.1" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (8.49e-3)" "unprognostic (3.93e-3)" "unprognostic (1.57e-1)" "unprognostic (5.50e-2)" "unprognostic (1.71e-2)" "prognostic favorable (4.00e-5)" "unprognostic (1.92e-2)" "unprognostic (6.65e-2)" "unprognostic (2.33e-2)" "unprognostic (1.99e-2)" "unprognostic (8.36e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (8.46e-11)" "unprognostic (9.05e-2)" "unprognostic (1.18e-1)" "unprognostic (9.80e-2)" "unprognostic (6.79e-2)" 63.6 17.6 0.1 90.8 0.3 65.4 23.8 0.1 1.5 37.9 1.0 30.0 11.6 22.8 0.3 32.2 104.4 8.4 6.7 0.1 0.6 72.8 42.4 194.9 346.3 2.8 0.1 13.4 6.3 0.1 6.8 0.1 0.4 41.4 8.8 0.0 69.9 12.7 1.9 2.3 100.9 1.6 1.2 1289.1 65.4 31.7 0.1 27.1 87.6 0.0 929.0 87.3 29.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.3 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 6.0 3.9 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.1 0.0 49.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 211.0 0.0 0.0 0.0 64.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 20.7 0.1 0.3 0.1 1.5 0.1 0.6 2.8 0.1 0.4 1.2 0.1 1.0 1.9 57.7 363.7 0.0 2548.4 0.0 9.7 0.0 0.0 0.0 0.5 0.1 1.9 18.6 11.2 0.0 0.0 0.0 2.0 7.0 0.0 0.0 6.5 0.1 0.2 5.3 13.2 24.5 0.0 0.0 0.0 9.1 2.6 0.0 195.5 0.0 22.9 64.2 0.1 0.0 0.0 7.4 0.0 62.8 0.0 16.4 0.0 7.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.6 0.0 4543.8 13.3 0.0 0.5 2.2 0.0 0.0 0.0 0.7 4.7 0.7 0.0 0.0 0.0 467.3 0.0 13.5 0.1 IGHJ1 ENSG00000211905 "Immunoglobulin heavy joining 1" A0A0C4DH62 14 105865407-105865458 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "intestine: 354.8;lymphoid tissue: 414.0;salivary gland: 120.1;stomach 1: 305.5" "Cell type enriched" "Detected in single" 18 "Plasma cells: 1.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 1.9" "Group enriched" "Detected in some" 72 "memory B-cell: 276.3;naive B-cell: 180.8;plasmacytoid DC: 99.0" "Group enriched" "Detected in many" 73 "B-cells: 276.3;dendritic cells: 99.0" "Cell line enhanced" "Detected in some" "SCLC-21H: 2.7;U-698: 1.8" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.28e-3)" "unprognostic (2.05e-2)" "unprognostic (6.81e-2)" "unprognostic (9.53e-2)" "prognostic favorable (3.55e-4)" "unprognostic (2.51e-1)" "unprognostic (2.45e-1)" "unprognostic (3.00e-2)" "unprognostic (2.90e-2)" 8.6 5.3 0.1 196.9 0.1 35.6 72.8 0.0 1.9 18.6 0.2 260.2 354.8 3.3 0.0 15.7 5.2 12.6 1.4 0.1 0.1 2.3 6.1 28.5 46.8 1.3 0.0 8.2 3.1 0.4 0.0 0.7 0.5 4.3 182.6 0.0 120.1 0.5 0.0 0.0 171.1 12.0 0.3 100.2 305.5 1.0 0.2 14.6 2.9 0.0 414.0 61.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.6 0.1 0.2 0.0 0.2 276.3 0.6 2.5 0.2 180.8 0.3 0.3 0.0 0.1 0.1 99.0 0.2 29.1 0.1 0.1 0.0 1.9 0.1 0.1 1.3 0.0 0.5 0.3 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHJ2 ENSG00000211904 "Immunoglobulin heavy joining 2" 14 105865199-105865250 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "cervix: 48.7;intestine: 127.5;lymphoid tissue: 174.5" "Cell type enriched" "Detected in single" 6 "Plasma cells: 3.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "medulla oblongata: 3.8" "Group enriched" "Detected in some" 18 "MAIT T-cell: 49.0;naive B-cell: 12.6" "Group enriched" "Detected in many" 45 "B-cells: 12.6;T-cells: 49.0" "Group enriched" "Detected in some" 25 "Daudi: 3.8;K-562: 1.1" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.03e-3)" "unprognostic (2.87e-2)" "unprognostic (1.81e-2)" "unprognostic (1.27e-2)" "prognostic favorable (1.05e-4)" "unprognostic (7.40e-2)" "unprognostic (6.38e-2)" "unprognostic (1.82e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.33e-6)" "unprognostic (4.31e-2)" "unprognostic (1.68e-1)" "unprognostic (5.48e-2)" "unprognostic (4.60e-1)" 2.0 0.0 0.2 0.0 0.5 13.3 20.5 0.2 2.0 48.7 0.1 87.2 0.0 5.4 17.9 18.0 2.1 0.8 0.1 0.2 0.4 1.2 12.0 0.0 7.6 3.8 0.8 7.7 18.9 0.6 0.0 0.0 0.5 15.0 127.5 0.0 0.0 7.1 0.0 0.0 0.0 5.8 0.6 18.8 18.2 0.1 0.5 19.6 5.1 0.0 174.5 6.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 49.0 1.3 0.4 1.6 0.4 12.6 0.0 0.2 0.2 0.0 0.6 0.0 0.0 17.1 0.2 0.5 0.2 2.0 0.2 0.4 3.8 0.8 0.5 0.6 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHJ3 ENSG00000242887 "Immunoglobulin heavy joining 3" 14 105864587-105864635 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 36.4;intestine: 57.9;pancreas: 61.6" "Cell type enriched" "Detected in single" 48 "Plasma cells: 24.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "basophil: 9.0;naive B-cell: 29.1" "Group enriched" "Detected in many" 7 "B-cells: 29.1;granulocytes: 9.0" "Cell line enhanced" "Detected in some" "Daudi: 1.5;RPMI-8226: 6.1;TIME: 8.0;U-251 MG: 2.6" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (8.67e-4)" "unprognostic (8.67e-3)" "unprognostic (1.12e-1)" "unprognostic (2.42e-2)" "prognostic favorable (3.86e-5)" "unprognostic (3.12e-1)" "unprognostic (2.21e-1)" "unprognostic (2.82e-1)" "unprognostic (4.22e-2)" "unprognostic (2.03e-1)" "unprognostic (5.70e-2)" "prognostic unfavorable (3.24e-4)" "unprognostic (8.47e-2)" "unprognostic (2.54e-1)" "unprognostic (9.62e-2)" "unprognostic (1.30e-1)" 16.2 3.0 0.6 0.0 0.9 0.0 0.0 0.2 2.5 1.9 0.5 0.0 0.0 0.0 0.0 36.4 0.7 9.1 0.0 0.6 0.9 0.9 10.2 17.3 0.0 1.5 0.4 11.3 61.6 0.0 0.0 0.0 1.7 7.5 57.9 0.1 0.0 4.3 0.0 2.4 0.0 0.0 1.4 0.0 0.0 0.3 0.7 0.0 2.4 0.0 0.0 5.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.4 0.2 0.0 0.9 0.0 0.7 1.1 2.6 29.1 1.5 1.2 0.0 0.4 0.7 0.0 1.2 0.0 0.6 0.9 0.2 2.5 0.6 0.9 1.5 0.4 1.7 1.4 0.7 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGHJ4 ENSG00000240041 "Immunoglobulin heavy joining 4" 14 105864215-105864260 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 416.7;lymphoid tissue: 1568.0;urinary bladder: 551.2" "Cell type enriched" "Detected in single" 148 "Plasma cells: 103.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 187 "memory B-cell: 6029.7;naive B-cell: 2618.0" "Lineage enriched" "Detected in all" 261 "B-cells: 6029.7" "Cell line enriched" "Detected in some" 87 "U-698: 3990.3" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" 0.0 0.0 7.2 0.0 2.9 0.0 240.0 0.9 10.8 0.0 3.6 377.5 0.0 0.0 0.0 200.2 7.4 4.1 12.3 0.9 2.5 0.0 39.1 0.0 0.0 8.9 30.7 0.0 0.0 13.6 0.0 2.5 22.3 7.0 416.7 0.0 0.0 0.0 0.0 20.7 0.0 0.0 2.0 45.4 7.3 3.7 3.1 32.3 3.9 0.0 1568.0 551.2 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 19.9 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 14.0 17.5 0.0 0.0 0.0 0.0 6.8 3.6 0.0 0.0 0.0 0.0 0.0 8.9 0.0 45.8 0.0 0.0 6.2 0.0 3990.3 0.0 12.2 0.0 13.9 3.6 5.4 5.0 1.3 3.0 6029.7 13.2 4.0 23.1 2618.0 1.5 6.0 20.1 3.3 6.0 0.0 6.6 1048.2 7.2 2.9 0.9 10.8 0.9 2.5 8.9 30.7 22.3 2.0 3.1 1.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 103.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHJ6 ENSG00000211900 "Immunoglobulin heavy joining 6" 14 105863198-105863258 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "cervix: 142.4;intestine: 38.6;lung: 47.0;testis: 151.4;urinary bladder: 113.5" "Cell type enriched" "Detected in single" 56 "Plasma cells: 39.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "memory B-cell: 316.2;naive B-cell: 112.7" "Lineage enriched" "Detected in many" 21 "B-cells: 316.2" "Cell line enhanced" "Detected in some" "U-266/84: 1.3;U-937: 1.2" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 71: Testis - DNA repair" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" 0.0 0.0 0.0 0.0 0.0 1.1 0.7 0.1 0.9 142.4 0.0 2.6 38.6 1.0 0.0 0.0 2.1 0.5 0.9 0.3 0.0 3.0 2.4 47.0 0.4 0.4 0.1 0.0 0.0 3.7 0.0 0.0 0.3 3.6 0.0 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.6 0.7 151.4 0.3 0.0 0.7 0.0 10.7 113.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1.2 0.0 3.5 3.5 0.8 0.3 0.0 0.2 316.2 0.5 0.6 0.5 112.7 0.6 0.3 14.8 0.2 1.0 0.0 0.1 89.2 0.0 0.0 0.1 0.9 0.3 0.0 0.4 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHM ENSG00000211899 "Immunoglobulin heavy constant mu" P01871 14 105851705-105856218 "Disease related genes, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 1315.0;lymphoid tissue: 4112.3" "Group enriched" "Detected in many" 14 "B-cells: 3757.1;Plasma cells: 9906.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 16 "memory B-cell: 4278.4;naive B-cell: 6731.2" "Lineage enriched" "Detected in all" 19 "B-cells: 6731.2" "Group enriched" "Detected in many" 9 "Daudi: 4983.6;U-698: 4905.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" CAB008643 Uncertain "Immunoglobulin genes" NA NA 110000000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB008643: AB_1617732" "unprognostic (2.91e-3)" "prognostic favorable (6.49e-4)" "unprognostic (9.30e-3)" "unprognostic (9.90e-3)" "unprognostic (2.05e-1)" "prognostic favorable (3.70e-6)" "unprognostic (9.61e-3)" "unprognostic (1.01e-1)" "unprognostic (1.52e-2)" "unprognostic (3.23e-3)" "unprognostic (2.46e-2)" "unprognostic (7.13e-2)" "prognostic unfavorable (5.20e-5)" "unprognostic (3.01e-1)" "unprognostic (1.76e-1)" "unprognostic (3.24e-2)" "unprognostic (6.28e-3)" 52.0 9.0 0.4 373.7 0.4 395.3 56.6 0.2 1.7 67.9 1.8 446.8 1204.9 11.1 10.2 66.8 38.5 141.7 50.5 0.2 0.4 48.4 84.7 180.6 3192.1 1.9 0.3 9.7 44.5 0.6 8.7 3.6 0.7 15.1 201.4 0.0 325.1 6.1 2.7 1.7 1315.0 7.9 1.0 4112.3 528.9 70.9 0.7 117.3 37.0 0.7 497.1 128.0 10.5 0.5 4.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 4983.6 2.9 0.0 0.0 0.8 0.0 0.0 0.0 21.6 0.0 3.0 0.0 0.0 0.0 2.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 1.7 28.7 1.2 0.0 0.0 580.2 2.2 6.9 0.0 0.0 4.0 5.8 3.0 0.5 1.2 0.0 0.2 3.8 6.5 0.0 13.8 1.2 2.5 1.5 1.5 4905.9 0.0 2.4 0.0 10.8 5.4 5.6 3.1 1.2 2.3 4278.4 5.5 6.8 5.4 6731.2 4.5 3.8 25.4 11.4 4.5 346.1 11.4 815.2 0.4 0.4 0.2 1.7 0.2 0.4 1.9 0.3 0.7 1.0 0.7 0.5 1.0 38.5 254.5 0.0 3757.1 0.0 0.2 0.0 1.2 0.0 2.2 0.8 0.3 31.5 14.2 0.0 0.0 0.0 63.8 1.8 0.0 0.0 0.0 0.0 0.1 4.2 6.7 474.1 0.0 0.0 0.0 10.8 27.5 0.0 152.6 0.0 56.7 147.9 0.1 0.0 0.0 2.2 0.0 158.1 0.0 0.0 0.0 12.4 0.0 0.0 5.2 0.0 11.3 0.0 0.0 0.0 1.2 0.0 9906.5 0.3 0.0 2.2 1.5 0.0 0.0 0.4 16.8 0.0 0.0 0.2 0.0 0.0 415.0 0.3 4.1 0.1 IGHV1-18 ENSG00000211945 "Immunoglobulin heavy variable 1-18" A0A0C4DH31 14 106184901-106185394 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 223.2;lymphoid tissue: 486.7;salivary gland: 234.3" "Cell type enriched" "Detected in some" 259 "Plasma cells: 13773.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 21 "memory B-cell: 73.2" "Lineage enriched" "Detected in many" 21 "B-cells: 73.2" "Cell line enhanced" "Detected in some" "Daudi: 1.6;HL-60: 3.0;RPMI-8226: 2.9;TIME: 1.6" "Immunoglobulin genes" NA NA 4700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.47e-4)" "unprognostic (2.53e-2)" "unprognostic (8.73e-3)" "unprognostic (2.56e-2)" "unprognostic (9.67e-3)" "prognostic favorable (8.27e-4)" "unprognostic (5.47e-2)" "unprognostic (3.52e-1)" "unprognostic (2.65e-1)" "unprognostic (3.50e-2)" "unprognostic (3.60e-1)" "unprognostic (4.26e-1)" "prognostic unfavorable (5.84e-7)" "unprognostic (3.22e-1)" "unprognostic (2.62e-1)" "unprognostic (2.87e-1)" "unprognostic (2.44e-2)" 22.0 3.5 0.0 0.0 0.3 0.0 22.9 0.0 0.6 54.6 0.0 223.2 0.0 8.9 4.5 162.5 24.3 7.7 2.3 0.0 0.0 16.2 14.3 58.3 0.0 0.6 0.1 8.5 3.2 1.9 1.3 0.2 0.4 10.8 0.0 0.0 234.3 0.0 0.4 1.3 103.2 2.6 0.0 486.7 84.0 0.5 0.1 0.0 33.9 0.2 0.0 156.1 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.9 0.0 0.0 0.0 0.6 0.5 0.8 0.0 0.0 1.1 1.2 2.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.5 0.4 1.0 0.5 0.0 0.3 0.0 1.4 0.0 3.4 0.0 0.1 0.0 0.0 0.1 73.2 0.0 0.0 0.1 0.0 0.1 0.0 1.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.6 0.1 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 50.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.5 53.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 13773.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 3.2 0.0 0.1 0.0 IGHV1-2 V35 ENSG00000211934 "Immunoglobulin heavy variable 1-2" P23083 14 105986582-105987083 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 462.7;lymphoid tissue: 1157.3" "Cell type enriched" "Detected in some" 38 "Plasma cells: 609.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 52 "memory B-cell: 285.2;naive B-cell: 347.4" "Lineage enriched" "Detected in many" 57 "B-cells: 347.4" "Cell line enriched" "Detected in some" 8 "U-266/70: 14302.7" "Immunoglobulin genes" NA NA 4000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.63e-3)" "unprognostic (1.09e-3)" "unprognostic (1.88e-1)" "unprognostic (9.46e-2)" "unprognostic (5.78e-2)" "prognostic favorable (1.67e-5)" "unprognostic (9.05e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-1)" "unprognostic (2.37e-1)" "unprognostic (1.99e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (2.02e-4)" "unprognostic (2.17e-2)" "unprognostic (8.59e-2)" "unprognostic (3.19e-1)" "unprognostic (1.17e-2)" 16.7 43.1 0.3 364.1 0.2 76.0 84.1 0.0 1.2 41.5 0.5 462.7 223.7 13.1 1.3 34.5 58.5 54.4 26.2 0.0 0.1 13.7 18.9 60.7 404.9 0.4 0.0 36.5 3.0 0.6 1.3 0.6 0.2 23.2 283.8 0.0 222.4 52.5 0.4 4.5 121.9 7.5 0.2 393.2 216.1 35.0 0.1 72.1 33.7 0.0 1157.3 255.5 8.9 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 4.3 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.8 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 2.6 0.0 0.0 2.3 0.4 2.8 0.0 0.0 3.1 0.6 0.5 0.0 0.0 1.3 1.8 0.1 0.0 0.6 0.0 0.0 0.2 0.3 0.0 1.5 0.0 1.3 14302.7 1755.5 0.5 0.0 0.4 0.0 0.3 0.6 0.1 0.3 0.0 0.2 285.2 1.6 0.7 0.2 347.4 1.5 0.6 6.1 0.2 0.3 0.5 1.1 34.0 0.3 0.2 0.0 1.2 0.0 0.1 0.4 0.0 0.2 0.2 0.1 0.6 0.0 0.0 1.3 0.0 15.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.1 4.6 0.0 0.0 0.2 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 609.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 IGHV1-24 ENSG00000211950 "Immunoglobulin heavy variable 1-24" A0A0C4DH33 14 106276548-106277043 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 186.8;salivary gland: 76.3" "Cell type enriched" "Detected in some" 4 "Plasma cells: 231.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "medulla oblongata: 1.2" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.8" "Lineage enriched" "Detected in single" 9 "B-cells: 2.8" "Cell line enhanced" "Detected in some" "Daudi: 1.0;HL-60: 1.8;JURKAT: 1.3;RH-30: 1.4" "Immunoglobulin genes" NA NA 3100000000 "Cluster 24: B-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (9.01e-4)" "unprognostic (2.67e-2)" "unprognostic (1.66e-2)" "unprognostic (1.93e-3)" "prognostic favorable (3.61e-4)" "unprognostic (1.28e-1)" "unprognostic (1.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.62e-1)" "unprognostic (1.59e-1)" "unprognostic (4.10e-1)" "prognostic unfavorable (2.07e-7)" "unprognostic (5.43e-2)" "unprognostic (3.14e-2)" "unprognostic (3.17e-1)" "unprognostic (4.78e-2)" 6.8 1.4 0.1 33.7 0.0 0.0 8.5 0.0 0.3 56.3 0.1 30.5 0.0 5.7 0.0 46.2 6.5 4.6 1.8 0.0 0.1 7.0 6.4 17.7 0.0 1.2 0.1 19.6 1.4 0.1 0.4 0.3 0.0 3.1 14.0 0.0 76.3 0.0 0.1 0.8 24.0 2.1 0.0 186.8 37.0 14.2 0.0 0.4 14.5 0.0 18.4 63.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.6 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.8 0.1 0.0 0.0 2.8 0.1 0.2 0.0 0.0 0.0 0.0 0.1 3.6 0.1 0.0 0.0 0.3 0.0 0.1 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.9 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 19.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 231.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 5.7 0.0 0.0 0.0 0.2 0.0 0.2 0.0 IGHV1-46 ENSG00000211962 "Immunoglobulin heavy variable 1-46" P01743 14 106511117-106511856 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 67.9;lymphoid tissue: 125.7;salivary gland: 67.4" "Cell type enriched" "Detected in some" 201 "Plasma cells: 8432.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.7;RPMI-8226: 1.2;SH-SY5Y: 1.2;TIME: 2.3;U-266/70: 1.1;U-266/84: 1.2" "Immunoglobulin genes" NA NA 2900000000 "Cluster 24: B-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.28e-4)" "unprognostic (2.49e-2)" "prognostic favorable (7.34e-4)" "unprognostic (1.10e-2)" "unprognostic (3.53e-2)" "unprognostic (1.80e-3)" "unprognostic (1.87e-1)" "unprognostic (6.76e-2)" "unprognostic (8.11e-2)" "unprognostic (2.57e-2)" "unprognostic (1.25e-1)" "unprognostic (3.27e-1)" "prognostic unfavorable (1.56e-6)" "unprognostic (6.19e-2)" "unprognostic (2.52e-1)" "unprognostic (2.27e-1)" "unprognostic (5.13e-1)" 5.1 1.3 0.0 0.0 0.0 0.0 7.2 0.0 0.1 6.2 0.0 67.9 0.0 2.5 1.0 4.9 3.5 0.7 5.0 0.0 0.0 3.2 4.2 15.3 0.0 0.1 0.0 3.0 5.3 0.1 0.3 0.3 0.1 1.9 45.1 0.0 67.4 0.0 0.1 0.7 34.2 0.0 0.0 125.7 25.1 0.2 0.0 0.0 10.5 0.2 0.0 5.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.0 0.5 1.2 0.2 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.3 0.0 0.1 1.1 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.7 0.0 0.0 0.0 1.9 41.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8432.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 IGHV1-69D ENSG00000280411 "Immunoglobulin heavy variable 1-69D" A0A0B4J2H0 14 106762092-106762588 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2878.6;stomach 1: 989.1" "Group enriched" "Detected in some" 6 "Plasma cells: 5.8;T-cells: 1.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 225 "memory B-cell: 184.5;naive B-cell: 433.4" "Lineage enriched" "Detected in many" 316 "B-cells: 433.4" "Cell line enhanced" "Detected in some" "Daudi: 2.8;HL-60: 2.3;MOLT-4: 4.2;RPMI-8226: 2.5;U-266/70: 3.3;U-698: 7.9" "Immunoglobulin genes" NA NA 1200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (3.32e-3)" "unprognostic (1.75e-2)" "unprognostic (3.87e-2)" "unprognostic (3.77e-2)" "unprognostic (2.49e-4)" "prognostic favorable (2.88e-4)" "unprognostic (1.66e-2)" "unprognostic (1.76e-1)" "unprognostic (1.01e-1)" "unprognostic (1.88e-2)" "unprognostic (1.62e-1)" "unprognostic (3.01e-1)" "prognostic unfavorable (2.72e-8)" "unprognostic (5.14e-2)" "unprognostic (9.96e-2)" "unprognostic (2.84e-2)" "unprognostic (2.08e-2)" 26.1 95.3 0.1 462.7 0.1 113.1 146.7 0.0 0.7 37.5 1.0 628.2 491.2 15.0 16.8 98.6 16.0 78.0 20.2 0.0 0.1 17.5 46.6 149.6 2878.6 1.1 0.0 35.9 3.3 0.6 1.1 0.4 0.1 16.5 406.2 0.0 385.0 100.0 0.5 5.2 121.3 43.8 0.2 452.7 989.1 6.8 0.0 135.7 38.3 0.0 2219.2 295.4 11.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 4.2 0.3 1.3 0.0 0.0 0.9 0.8 2.5 0.0 0.0 0.8 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.6 0.4 3.3 0.1 7.9 0.0 0.7 0.0 0.8 0.3 0.1 0.0 0.0 0.2 184.5 0.3 0.0 0.2 433.4 0.4 0.1 0.4 0.2 0.4 1.3 0.2 33.5 0.1 0.1 0.0 0.7 0.0 0.1 1.1 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGHV2-26 ENSG00000211951 "Immunoglobulin heavy variable 2-26" A0A0B4J1V2 14 106301396-106301862 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 128.8;lymphoid tissue: 98.5;urinary bladder: 227.1" "Group enriched" "Detected in some" 39 "B-cells: 8.3;Plasma cells: 7.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 14 "memory B-cell: 13.9" "Lineage enriched" "Detected in single" 140 "B-cells: 13.9" "Cell line enhanced" "Detected in some" "HL-60: 1.3;RH-30: 1.4" "Immunoglobulin genes" NA NA 190000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 57: B-cells - Immune response" "unprognostic (9.39e-3)" "unprognostic (4.50e-2)" "unprognostic (7.66e-3)" "unprognostic (2.94e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-2)" "unprognostic (1.18e-1)" "unprognostic (1.67e-1)" "unprognostic (1.72e-1)" "unprognostic (2.13e-2)" "unprognostic (4.99e-1)" "prognostic unfavorable (4.99e-5)" "unprognostic (6.68e-2)" "unprognostic (2.61e-1)" "unprognostic (2.24e-1)" "unprognostic (8.09e-2)" 6.2 7.7 0.0 59.0 0.0 21.6 14.0 0.0 0.3 15.5 0.2 35.0 61.5 4.2 0.0 31.5 3.8 128.8 5.6 0.0 0.4 2.3 6.0 20.7 3.5 0.2 0.6 0.5 1.6 0.0 0.3 0.0 0.1 6.3 86.5 0.0 44.2 0.9 0.1 0.5 55.1 4.4 0.2 98.5 65.1 0.0 1.1 0.0 6.8 0.0 21.8 227.1 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.4 0.2 0.6 0.1 0.2 1.1 0.2 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGHV2-5 ENSG00000211937 "Immunoglobulin heavy variable 2-5" P01817 14 106037902-106038365 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 465.8;lymphoid tissue: 1426.6;stomach 1: 707.9" "Cell type enriched" "Detected in some" 333 "Plasma cells: 9414.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "memory B-cell: 66.7;naive B-cell: 67.3" "Lineage enriched" "Detected in many" 22 "B-cells: 67.3" "Cell line enriched" "Detected in some" 5 "Karpas-707: 8.8" "Immunoglobulin genes" NA NA 700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.38e-2)" "unprognostic (4.10e-3)" "unprognostic (2.51e-2)" "unprognostic (6.62e-3)" "prognostic favorable (1.41e-4)" "unprognostic (1.66e-1)" "unprognostic (1.35e-1)" "unprognostic (3.63e-1)" "unprognostic (1.47e-1)" "unprognostic (8.45e-2)" "unprognostic (3.38e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.74e-2)" "unprognostic (1.69e-1)" "unprognostic (4.15e-1)" "unprognostic (1.56e-1)" 16.9 5.0 0.0 183.0 0.2 112.8 106.0 0.0 0.5 45.0 0.2 465.8 266.6 7.5 2.5 27.9 10.7 65.0 5.8 0.0 0.1 20.9 16.4 83.9 188.0 0.5 0.2 13.8 9.3 1.0 1.1 0.3 0.7 9.4 296.3 0.0 201.4 8.8 0.4 2.9 177.0 17.4 0.3 351.0 707.9 2.3 0.0 121.5 27.6 0.0 1426.6 249.3 12.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 8.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.2 1.6 0.4 0.0 0.1 1.2 1.8 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.3 0.4 0.6 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 66.7 0.0 0.0 0.1 67.3 0.1 0.1 3.0 0.0 0.0 0.0 0.0 10.5 0.0 0.2 0.0 0.5 0.0 0.1 0.5 0.2 0.7 0.3 0.0 0.4 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.1 27.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 3.4 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9414.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 IGHV3-11 ENSG00000211941 "Immunoglobulin heavy variable 3-11" P01762 14 106116635-106117204 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 220.1;lymphoid tissue: 613.1;stomach 1: 206.7" "Cell type enriched" "Detected in some" 142 "Plasma cells: 1655.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 445 "memory B-cell: 43.1;naive B-cell: 45.7" "Lineage enriched" "Detected in single" 458 "B-cells: 45.7" "Cell line enhanced" "Detected in some" "Daudi: 1.1;SH-SY5Y: 1.2" "Immunoglobulin genes" NA NA 18000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.07e-3)" "unprognostic (4.84e-2)" "unprognostic (5.81e-3)" "unprognostic (1.07e-2)" "unprognostic (1.04e-2)" "prognostic favorable (3.42e-5)" "unprognostic (4.12e-1)" "unprognostic (6.50e-2)" "unprognostic (2.37e-1)" "unprognostic (3.44e-2)" "unprognostic (3.51e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (1.43e-1)" "unprognostic (2.97e-1)" "unprognostic (1.86e-1)" "unprognostic (1.30e-1)" 9.3 25.9 0.0 175.0 0.0 38.0 66.0 0.0 0.5 34.7 0.2 220.1 193.4 6.8 12.3 38.6 6.6 43.7 8.6 0.0 0.0 6.8 10.5 29.1 123.7 0.8 0.0 7.8 2.0 0.2 0.8 0.0 0.1 4.0 167.9 0.0 119.7 3.7 0.3 0.7 116.8 11.2 0.1 219.2 206.7 1.3 0.4 44.9 17.0 0.0 613.1 109.4 8.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.7 0.7 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 45.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.5 0.0 0.0 0.8 0.0 0.1 0.1 0.4 0.2 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.6 0.0 0.0 0.0 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1655.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 IGHV3-13 ENSG00000211942 "Immunoglobulin heavy variable 3-13" P01766 14 106129540-106130072 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 67.5;lymphoid tissue: 137.3;urinary bladder: 90.5" "Group enriched" "Detected in some" 6 "B-cells: 6.7;Plasma cells: 13.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 193 "memory B-cell: 18.8;naive B-cell: 19.6" "Lineage enriched" "Detected in single" 197 "B-cells: 19.6" "Cell line enhanced" "Detected in some" "MOLT-4: 1.8;U-266/70: 1.0" "Immunoglobulin genes" NA NA 33000000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "prognostic favorable (3.24e-4)" "unprognostic (7.42e-2)" "unprognostic (1.96e-2)" "unprognostic (5.03e-2)" "prognostic favorable (6.67e-6)" "unprognostic (5.44e-2)" "unprognostic (1.23e-2)" "unprognostic (1.53e-1)" "unprognostic (5.31e-2)" "unprognostic (8.27e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (7.21e-5)" "unprognostic (6.79e-2)" "unprognostic (3.21e-1)" "unprognostic (4.45e-1)" "unprognostic (7.87e-2)" 1.3 36.6 0.0 24.1 0.0 6.9 17.2 0.0 0.1 1.9 0.0 67.5 49.5 1.5 0.0 15.4 4.3 9.7 1.8 0.0 0.0 1.1 1.5 7.2 39.5 0.0 0.1 1.5 0.7 0.0 0.1 0.0 0.0 1.1 36.1 0.0 30.9 1.4 0.0 0.1 22.8 5.6 0.1 56.5 42.9 0.9 0.0 9.3 2.8 0.0 137.3 90.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.8 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.8 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 IGHV3-15 ENSG00000211943 "Immunoglobulin heavy variable 3-15" A0A0B4J1V0 14 106153624-106154163 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 183.3;lymphoid tissue: 380.2;salivary gland: 177.7;stomach 1: 112.8;urinary bladder: 172.6" "Cell type enriched" "Detected in some" 112 "Plasma cells: 6281.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 9 "MAIT T-cell: 21.6;memory B-cell: 24.4" "Group enriched" "Detected in many" 9 "B-cells: 24.4;T-cells: 21.6" "Cell line enhanced" "Detected in some" "BEWO: 2.2;Daudi: 1.9;HL-60: 2.1;K-562: 2.0;NB-4: 2.4;RH-30: 1.9;RPMI-8226: 4.1;SH-SY5Y: 3.7" "Immunoglobulin genes" NA NA 20000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (8.85e-5)" "unprognostic (2.07e-1)" "unprognostic (1.94e-2)" "unprognostic (1.41e-2)" "unprognostic (1.62e-2)" "prognostic favorable (3.34e-5)" "unprognostic (5.20e-2)" "unprognostic (2.44e-1)" "unprognostic (9.67e-2)" "unprognostic (3.24e-2)" "unprognostic (2.53e-1)" "unprognostic (2.19e-1)" "prognostic unfavorable (1.49e-7)" "unprognostic (6.85e-2)" "unprognostic (6.92e-2)" "unprognostic (7.12e-2)" "unprognostic (3.63e-1)" 12.2 36.8 0.0 24.7 0.5 1.8 23.2 0.0 1.2 13.0 0.1 183.3 4.5 5.0 0.9 11.7 16.3 29.6 1.4 0.0 0.2 9.1 10.6 40.0 0.0 1.0 0.0 5.8 19.1 0.4 1.3 0.4 0.3 9.5 14.6 0.0 177.7 23.0 0.8 4.2 107.2 0.3 0.0 380.2 112.8 0.5 0.0 0.0 14.9 0.0 10.4 172.6 9.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.8 2.4 0.7 0.0 0.0 0.0 1.9 4.1 0.0 0.0 0.0 3.7 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.6 0.1 0.4 1.6 0.0 0.2 0.0 0.3 0.0 0.2 0.2 0.1 0.1 0.0 21.6 24.4 0.1 0.2 0.2 0.0 0.2 0.1 2.5 0.0 0.0 0.2 0.1 1.8 0.0 0.5 0.0 1.2 0.0 0.2 1.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 56.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 1.1 8.2 0.0 0.0 0.1 1.1 0.6 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6281.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 IGHV3-21 ENSG00000211947 "Immunoglobulin heavy variable 3-21" A0A0B4J1V1 14 106235064-106235594 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 209.7;lymphoid tissue: 398.1;salivary gland: 213.2" "Cell type enriched" "Detected in some" 86 "Plasma cells: 3885.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 2.1;NB-4: 2.1;NTERA-2: 1.2;RH-30: 2.3;TIME: 1.9" "Immunoglobulin genes" NA NA 37000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.30e-4)" "unprognostic (1.21e-2)" "unprognostic (7.19e-3)" "unprognostic (1.51e-2)" "unprognostic (9.16e-3)" "prognostic favorable (9.34e-4)" "unprognostic (3.15e-2)" "unprognostic (1.76e-1)" "unprognostic (4.42e-2)" "unprognostic (3.03e-2)" "unprognostic (2.48e-1)" "unprognostic (4.05e-1)" "prognostic unfavorable (9.31e-8)" "unprognostic (1.73e-1)" "unprognostic (3.19e-1)" "unprognostic (1.35e-1)" "unprognostic (1.77e-1)" 18.1 2.7 0.3 0.0 0.3 0.0 24.8 0.2 1.1 16.8 0.3 209.7 0.0 7.1 0.9 17.4 30.9 0.0 2.0 0.2 0.3 15.4 10.7 55.3 0.0 0.4 0.3 2.9 16.2 2.3 1.3 0.6 0.4 7.2 0.0 0.0 213.2 0.3 0.4 4.3 111.3 0.8 0.4 398.1 83.0 0.4 0.3 0.0 25.6 0.0 0.0 27.7 10.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 2.1 1.2 0.0 0.0 0.7 2.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.3 0.2 1.1 0.2 0.3 0.4 0.3 0.4 0.4 0.3 1.0 0.0 0.0 0.0 0.0 44.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 1.0 21.4 0.0 0.0 0.1 0.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3885.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 IGHV3-23 ENSG00000211949 "Immunoglobulin heavy variable 3-23" P01764 14 106268606-106269140 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1683.1;lymphoid tissue: 2989.8" "Cell type enriched" "Detected in some" 139 "Plasma cells: 15979.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 406 "memory B-cell: 548.5;naive B-cell: 336.7" "Lineage enriched" "Detected in many" 503 "B-cells: 548.5" "Cell line enhanced" "Detected in some" "BEWO: 4.4;HL-60: 3.3;NB-4: 4.1;RH-30: 3.0;RPMI-8226: 9.0;SH-SY5Y: 5.8" "Immunoglobulin genes" NA NA 42000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.17e-3)" "unprognostic (5.43e-2)" "unprognostic (9.68e-3)" "unprognostic (3.31e-3)" "unprognostic (1.34e-2)" "prognostic favorable (3.85e-4)" "unprognostic (3.26e-1)" "unprognostic (4.79e-1)" "unprognostic (7.26e-2)" "unprognostic (6.52e-3)" "unprognostic (1.72e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.79e-7)" "unprognostic (6.22e-2)" "unprognostic (1.84e-1)" "unprognostic (1.36e-1)" "unprognostic (6.42e-2)" 66.5 189.3 0.4 912.2 0.4 185.5 343.1 0.1 2.1 80.1 1.5 1683.1 1640.8 37.0 9.8 342.6 30.1 231.2 46.4 0.1 0.3 27.3 56.4 248.7 859.5 0.8 0.1 42.6 31.0 1.5 2.7 0.9 0.4 35.3 1087.1 0.1 697.8 53.4 0.9 15.0 886.8 40.0 0.8 802.7 1058.8 35.0 0.2 197.5 52.3 0.1 2989.8 993.6 27.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.2 4.1 0.7 0.0 0.0 0.6 3.0 9.0 0.0 0.0 2.7 5.8 0.8 0.1 0.0 0.0 0.0 0.0 1.8 0.0 1.3 1.3 1.1 1.5 0.0 0.3 0.0 0.9 0.0 0.4 0.4 0.1 0.2 0.0 0.1 548.5 0.2 0.3 0.3 336.7 0.1 0.2 1.0 0.2 0.2 0.2 0.8 62.4 0.4 0.4 0.1 2.1 0.1 0.3 0.8 0.1 0.4 0.8 0.2 1.4 0.1 0.0 0.0 0.0 114.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 12.0 0.0 0.0 0.0 1.6 19.4 0.0 1.3 0.0 1.8 2.0 0.2 0.0 0.0 0.1 0.0 4.1 0.0 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15979.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.1 0.0 IGHV3-30 ENSG00000270550 "Immunoglobulin heavy variable 3-30" "P01768, P0DP03" 14 106335082-106335613 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 534.0;lymphoid tissue: 1294.8;salivary gland: 459.9;stomach 1: 572.6;urinary bladder: 378.9" "Cell type enriched" "Detected in some" 184 "Plasma cells: 14426.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 409 "memory B-cell: 164.0;naive B-cell: 136.6" "Lineage enriched" "Detected in single" 446 "B-cells: 164.0" "Cell line enhanced" "Detected in some" "BEWO: 2.1;Daudi: 1.7;NB-4: 2.3;RPMI-8226: 1.7;SCLC-21H: 1.7;SH-SY5Y: 3.0;U-266/70: 1.3" "Immunoglobulin genes" NA NA 8500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.12e-3)" "unprognostic (5.51e-2)" "unprognostic (1.05e-1)" "unprognostic (1.81e-3)" "unprognostic (1.72e-2)" "prognostic favorable (3.23e-5)" "unprognostic (7.43e-2)" "unprognostic (2.09e-1)" "unprognostic (1.95e-2)" "unprognostic (2.94e-2)" "unprognostic (2.94e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (1.65e-7)" "unprognostic (1.32e-1)" "unprognostic (2.16e-1)" "unprognostic (2.01e-1)" "unprognostic (6.96e-2)" 25.3 38.5 0.1 320.5 0.2 119.7 143.9 0.0 0.4 49.3 0.5 534.0 265.5 13.3 0.0 134.6 44.8 146.5 30.3 0.4 0.2 29.2 25.1 128.2 374.9 0.6 0.2 23.0 12.3 0.7 3.3 0.7 0.2 18.6 254.9 0.0 459.9 20.4 0.9 3.5 296.1 23.6 0.1 797.4 572.6 5.9 0.1 158.2 76.6 0.1 1294.8 378.9 34.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 1.0 1.7 0.0 0.0 1.7 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 1.3 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.1 164.0 0.2 0.0 0.1 136.6 0.3 0.1 0.3 0.0 0.0 0.2 0.0 24.4 0.1 0.2 0.0 0.4 0.4 0.2 0.6 0.2 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 78.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 5.4 16.3 0.0 1.3 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14426.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.4 0.0 IGHV3-33 ENSG00000211955 "Immunoglobulin heavy variable 3-33" P01772 14 106359793-106360324 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1066.7;lymphoid tissue: 2371.2;stomach 1: 1778.8" "Cell type enriched" "Detected in some" 26 "Plasma cells: 556.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 4.0" "Group enriched" "Detected in many" 101 "memory B-cell: 378.9;naive B-cell: 364.1" "Lineage enriched" "Detected in many" 103 "B-cells: 378.9" "Cell line enhanced" "Detected in some" "HDLM-2: 5.4;HL-60: 5.3;RPMI-8226: 7.7;SH-SY5Y: 3.8;U-266/70: 8.1" "Immunoglobulin genes" NA NA 7500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.04e-3)" "unprognostic (2.38e-2)" "unprognostic (8.95e-3)" "prognostic favorable (6.36e-4)" "unprognostic (6.84e-2)" "prognostic favorable (7.19e-5)" "unprognostic (1.80e-1)" "unprognostic (1.95e-1)" "unprognostic (7.31e-2)" "unprognostic (3.82e-2)" "unprognostic (1.70e-1)" "unprognostic (5.18e-1)" "prognostic unfavorable (4.10e-6)" "unprognostic (6.23e-2)" "unprognostic (1.69e-1)" "unprognostic (3.26e-1)" "unprognostic (5.92e-2)" 27.9 67.4 1.0 513.8 0.8 117.8 289.5 0.2 4.0 53.6 2.4 1066.7 882.1 16.2 14.5 127.5 18.9 141.9 32.9 0.2 0.4 15.7 41.8 210.1 795.2 1.4 0.2 110.0 29.4 1.9 1.7 0.8 0.4 23.2 775.6 0.0 619.6 39.5 0.5 3.6 343.9 37.3 0.5 476.1 1778.8 29.4 0.7 296.8 42.2 0.1 2371.2 379.8 18.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 5.4 0.0 0.5 0.0 0.0 0.0 5.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.1 0.8 0.0 0.0 0.5 0.2 0.3 0.0 0.0 0.8 2.9 7.7 0.0 0.0 1.4 3.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.3 0.7 8.1 0.0 0.2 0.0 0.8 0.0 0.2 0.6 0.1 1.1 0.0 1.9 378.9 3.6 0.9 0.3 364.1 1.4 0.6 1.0 0.2 0.1 0.2 0.5 44.6 1.0 0.8 0.2 4.0 0.2 0.4 1.4 0.2 0.4 0.5 0.7 0.7 0.0 0.0 0.6 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 10.0 2.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 556.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 IGHV3-49 ENSG00000211965 "Immunoglobulin heavy variable 3-49" A0A0A0MS15 14 106556936-106557477 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 210.7;lymphoid tissue: 373.5;stomach 1: 182.3" "Cell type enriched" "Detected in some" 46 "Plasma cells: 717.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 187 "memory B-cell: 59.4;naive B-cell: 42.2" "Lineage enriched" "Detected in single" 219 "B-cells: 59.4" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.0" "Immunoglobulin genes" NA NA 1600000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (7.16e-4)" "unprognostic (7.91e-3)" "unprognostic (2.50e-2)" "unprognostic (1.66e-2)" "unprognostic (2.12e-1)" "prognostic favorable (2.34e-6)" "unprognostic (4.47e-2)" "unprognostic (4.30e-2)" "unprognostic (7.00e-3)" "unprognostic (9.17e-2)" "unprognostic (2.18e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (1.43e-6)" "unprognostic (7.42e-2)" "unprognostic (2.79e-1)" "unprognostic (8.96e-2)" "unprognostic (3.00e-1)" 20.8 7.1 0.0 112.3 0.0 45.7 42.5 0.0 0.5 11.5 0.3 210.7 184.4 4.6 3.9 20.0 5.1 10.9 9.4 0.0 0.2 5.0 12.8 43.2 108.6 0.7 0.0 26.5 1.7 0.2 0.4 0.0 0.3 3.0 139.3 0.0 88.5 12.1 0.2 0.4 88.2 11.5 0.1 183.1 182.3 1.8 0.1 21.4 9.7 0.0 373.5 100.0 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.4 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.4 0.0 0.0 0.0 42.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.5 0.0 0.2 0.7 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 15.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 4.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 717.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 IGHV3-53 ENSG00000211967 "Immunoglobulin heavy variable 3-53" P01767 14 106592676-106593347 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 81.5;lymphoid tissue: 129.5;stomach 1: 43.3" "Cell type enriched" "Detected in some" 22 "Plasma cells: 176.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 99 "memory B-cell: 54.7;naive B-cell: 52.7" "Lineage enriched" "Detected in single" 101 "B-cells: 54.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 4300000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.41e-3)" "unprognostic (1.12e-1)" "unprognostic (2.46e-3)" "prognostic favorable (5.66e-4)" "prognostic favorable (3.95e-4)" "unprognostic (3.91e-2)" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (6.82e-2)" "unprognostic (1.19e-1)" "unprognostic (3.36e-2)" "prognostic unfavorable (2.04e-5)" "unprognostic (1.79e-1)" "unprognostic (8.26e-2)" "unprognostic (2.64e-1)" "unprognostic (3.72e-1)" 2.9 0.8 0.0 37.1 0.0 7.9 15.5 0.0 0.1 4.7 0.0 66.5 81.5 1.0 0.3 4.1 1.9 6.7 1.4 0.0 0.0 1.8 2.8 7.7 38.5 0.1 0.0 3.2 1.3 0.1 0.1 0.0 0.0 1.1 74.0 0.0 32.2 1.9 0.0 0.3 33.9 2.3 0.0 66.9 43.3 1.6 0.0 8.2 4.6 0.0 129.5 10.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 54.7 0.0 0.0 0.0 52.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 176.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGHV3-66 ENSG00000211972 "Immunoglobulin heavy variable 3-66" A0A0C4DH42 14 106675017-106675544 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 47.3;intestine: 59.5;urinary bladder: 103.9" "Cell type enriched" "Detected in some" 107 "Plasma cells: 958.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 137 "memory B-cell: 39.7" "Lineage enriched" "Detected in single" 137 "B-cells: 39.7" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.7;U-2 OS: 2.3" "Immunoglobulin genes" NA NA 7200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.43e-6)" "unprognostic (2.48e-2)" "unprognostic (5.05e-3)" "unprognostic (1.31e-3)" "unprognostic (2.20e-3)" "unprognostic (8.65e-2)" "unprognostic (1.59e-1)" "unprognostic (4.83e-2)" "unprognostic (1.87e-2)" "unprognostic (6.95e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.89e-6)" "unprognostic (3.87e-1)" "unprognostic (1.21e-1)" "unprognostic (2.84e-1)" "unprognostic (1.19e-1)" 3.8 0.9 0.0 0.0 0.1 11.1 3.9 0.0 0.4 15.3 0.3 59.5 0.0 1.4 1.2 27.0 3.2 47.3 0.3 0.0 0.0 1.3 3.5 13.1 41.1 0.2 0.0 5.6 0.4 0.0 0.1 0.0 0.0 3.9 32.3 0.0 16.1 5.7 0.0 1.5 10.1 1.3 0.0 31.8 6.3 0.6 0.0 0.0 2.5 0.0 39.7 103.9 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 39.7 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 958.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGHV3-7 ENSG00000211938 "Immunoglobulin heavy variable 3-7" P01780 14 106062151-106062683 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 461.3;lymphoid tissue: 971.3" "Cell type enriched" "Detected in some" 255 "Plasma cells: 20463.1" "Cancer enhanced" "Detected in many" "stomach cancer: 18.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 147 "memory B-cell: 134.0;naive B-cell: 107.0" "Lineage enriched" "Detected in single" 163 "B-cells: 134.0" "Cell line enhanced" "Detected in some" "Daudi: 7.6;HL-60: 3.1;K-562: 3.0;NB-4: 3.0;RPMI-8226: 5.8;SH-SY5Y: 4.8;TIME: 2.9" "Immunoglobulin genes" NA NA 39000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.29e-2)" "unprognostic (5.57e-3)" "unprognostic (1.37e-2)" "prognostic favorable (1.47e-6)" "unprognostic (1.00e-2)" "unprognostic (2.74e-1)" "unprognostic (1.28e-1)" "unprognostic (5.46e-2)" "unprognostic (1.37e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (4.35e-5)" "unprognostic (5.18e-2)" "unprognostic (8.50e-2)" "unprognostic (1.63e-1)" "unprognostic (7.70e-2)" 47.8 10.1 0.7 50.1 1.0 71.1 202.7 0.3 0.8 87.4 0.6 461.3 154.1 37.7 8.2 17.8 13.4 37.0 2.2 0.2 0.4 17.6 20.3 56.4 102.5 1.6 2.8 24.7 4.8 2.9 1.8 0.3 2.3 9.2 303.5 0.0 265.5 22.9 1.3 9.6 206.0 3.6 3.9 610.4 230.4 13.2 0.4 0.0 21.1 0.1 971.3 42.9 14.8 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.0 0.0 0.0 0.0 0.0 3.0 0.5 0.0 0.0 0.4 2.6 5.8 0.0 0.0 2.3 4.8 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.7 0.0 1.2 1.6 0.0 0.1 0.0 0.6 0.0 0.4 0.8 0.2 0.1 0.0 0.2 134.0 0.2 0.2 0.3 107.0 0.1 0.1 0.1 0.1 0.2 0.6 0.2 12.6 0.7 1.0 0.3 0.8 0.2 0.4 1.6 2.8 2.3 3.9 0.4 1.3 0.0 0.0 0.0 0.0 80.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 30.5 0.0 5.3 0.0 0.0 0.0 4.4 31.1 0.0 0.0 0.0 2.2 1.9 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.3 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20463.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 7.4 0.0 0.5 0.0 IGHV3-73 ENSG00000211976 "Immunoglobulin heavy variable 3-73" A0A0B4J1V6 14 106802694-106803233 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 141.8;lymphoid tissue: 83.0;urinary bladder: 81.7" "Cell type enhanced" "Detected in some" "B-cells: 6.1;Cholangiocytes: 1.5;Erythroid cells: 5.3;Plasma cells: 3.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 86 "memory B-cell: 69.9;naive B-cell: 42.9" "Lineage enriched" "Detected in single" 107 "B-cells: 69.9" "Cell line enhanced" "Detected in some" "Daudi: 1.4;HEL: 1.1;HL-60: 1.1;K-562: 1.7" "Immunoglobulin genes" NA NA 3200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 57: B-cells - Immune response" "prognostic favorable (7.89e-4)" "unprognostic (3.61e-2)" "unprognostic (1.55e-2)" "unprognostic (8.79e-2)" "prognostic favorable (7.25e-7)" "unprognostic (4.23e-2)" "unprognostic (4.32e-2)" "unprognostic (5.40e-1)" "unprognostic (1.57e-2)" "unprognostic (2.27e-2)" "unprognostic (5.37e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (4.45e-1)" "unprognostic (2.52e-1)" "unprognostic (5.25e-2)" "unprognostic (4.37e-2)" 4.4 13.3 0.0 9.4 0.0 15.8 10.5 0.0 0.5 4.7 0.3 76.9 141.8 5.1 0.0 4.0 3.9 19.1 10.4 0.0 0.0 3.0 9.8 12.3 0.0 0.1 0.0 1.5 5.9 0.0 0.5 0.1 0.2 4.3 58.0 0.0 30.6 3.9 0.4 0.2 23.6 0.4 0.1 83.0 47.5 0.4 0.0 0.0 4.1 0.0 0.2 81.7 2.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 69.9 0.1 0.0 0.0 42.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 IGHV3-74 ENSG00000224650 "Immunoglobulin heavy variable 3-74" A0A0B4J1X5 14 106810442-106811131 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 103.9;lymphoid tissue: 327.0;salivary gland: 102.6" "Cell type enriched" "Detected in some" 454 "Plasma cells: 19404.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.2" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 861 "Daudi: 2948.0" "Immunoglobulin genes" NA NA 27000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.47e-4)" "unprognostic (9.70e-2)" "prognostic favorable (8.33e-4)" "unprognostic (6.96e-3)" "unprognostic (1.42e-1)" "prognostic favorable (7.79e-4)" "unprognostic (1.06e-1)" "unprognostic (7.06e-2)" "unprognostic (3.94e-1)" "unprognostic (3.07e-2)" "unprognostic (2.42e-1)" "unprognostic (9.85e-2)" "prognostic unfavorable (4.70e-6)" "unprognostic (1.14e-1)" "unprognostic (2.54e-1)" "unprognostic (1.04e-1)" "unprognostic (1.12e-1)" 11.3 1.2 0.1 0.0 0.2 0.0 12.6 0.0 1.5 9.3 0.0 103.9 0.0 2.1 1.9 87.3 2.6 1.3 0.7 0.0 0.3 4.7 6.6 22.2 0.0 0.6 0.0 2.5 1.9 0.6 0.8 0.1 0.2 6.5 0.0 0.0 102.6 0.0 0.5 3.2 74.1 0.0 0.3 327.0 27.5 0.2 0.1 0.0 7.7 0.0 0.0 46.4 5.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 2948.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.1 1.1 0.2 0.0 0.0 0.1 1.2 0.0 0.1 0.1 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.7 0.3 0.4 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 1.2 0.9 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 1.5 0.0 0.3 0.6 0.0 0.2 0.3 0.1 0.2 0.0 0.0 0.0 0.0 42.7 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 1.4 27.5 0.2 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.6 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 19404.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 2.3 0.0 0.1 0.3 IGHV4-28 ENSG00000211952 "Immunoglobulin heavy variable 4-28" A0A0C4DH34 14 106324254-106324760 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 44.8;lymphoid tissue: 87.4;salivary gland: 39.9;stomach 1: 30.7;urinary bladder: 122.6" "Cell type enriched" "Detected in some" 230 "Plasma cells: 346.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 5 "spinal cord: 1.3" "Group enriched" "Detected in some" 206 "memory B-cell: 28.7;naive B-cell: 12.5" "Lineage enriched" "Detected in single" 288 "B-cells: 28.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 2500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.14e-3)" "unprognostic (1.32e-2)" "unprognostic (8.05e-2)" "unprognostic (6.64e-3)" "prognostic favorable (2.63e-4)" "unprognostic (1.58e-2)" "unprognostic (7.52e-2)" "unprognostic (1.03e-1)" "unprognostic (5.74e-2)" "unprognostic (4.76e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (4.79e-6)" "unprognostic (1.45e-1)" "unprognostic (1.28e-1)" "unprognostic (2.72e-1)" "unprognostic (1.75e-1)" 1.8 11.3 0.0 40.9 0.0 6.0 12.9 0.0 0.2 3.3 0.1 44.8 44.8 1.0 0.0 12.5 1.9 7.7 1.2 0.0 0.0 1.8 2.4 8.9 10.0 0.0 0.0 3.5 0.4 0.0 0.2 0.0 0.0 0.8 44.1 0.0 39.9 1.7 0.0 0.5 30.2 2.0 1.3 42.3 30.7 0.5 0.0 5.8 4.3 0.0 87.4 122.6 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.7 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 346.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGHV4-31 ENSG00000231475 "Immunoglobulin heavy variable 4-31" A0A087WSY4 14 106349283-106349792 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 467.7;urinary bladder: 190.8" "Cell type enriched" "Detected in some" 183 "Plasma cells: 1651.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "spinal cord: 1.6" "Group enriched" "Detected in some" 48 "memory B-cell: 43.6;naive B-cell: 19.4" "Lineage enriched" "Detected in single" 66 "B-cells: 43.6" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.4;SH-SY5Y: 1.0" "Immunoglobulin genes" NA NA 710000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.53e-3)" "unprognostic (9.05e-2)" "unprognostic (1.12e-1)" "prognostic favorable (5.74e-4)" "prognostic favorable (4.64e-5)" "unprognostic (1.16e-2)" "unprognostic (2.22e-1)" "unprognostic (1.04e-1)" "unprognostic (5.05e-2)" "unprognostic (1.72e-2)" "unprognostic (9.75e-2)" "prognostic unfavorable (6.38e-6)" "unprognostic (2.00e-1)" "unprognostic (1.48e-1)" "unprognostic (3.63e-1)" "unprognostic (1.09e-1)" 4.3 1.7 0.0 48.0 0.0 5.4 37.6 0.0 0.3 15.4 0.0 103.8 72.1 6.5 1.5 32.2 5.3 105.2 11.7 0.0 0.7 3.9 6.3 19.1 104.0 0.2 0.2 58.0 4.7 0.2 0.5 0.0 0.1 11.4 24.9 0.0 53.2 8.4 0.1 1.3 90.4 3.1 1.6 138.6 87.8 1.3 0.2 76.0 15.7 0.0 467.7 190.8 4.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.6 0.1 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.7 0.2 0.2 0.1 1.6 0.2 0.1 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1651.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGHV4-34 ENSG00000211956 "Immunoglobulin heavy variable 4-34" P06331 14 106373663-106374145 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 283.3;urinary bladder: 278.5" "Cell type enriched" "Detected in some" 197 "Plasma cells: 15696.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 602 "U-698: 5353.4" "Immunoglobulin genes" NA NA 4300000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.34e-3)" "unprognostic (1.32e-1)" "unprognostic (2.25e-2)" "unprognostic (5.34e-3)" "unprognostic (6.12e-2)" "prognostic favorable (2.77e-4)" "unprognostic (8.06e-2)" "unprognostic (3.89e-1)" "unprognostic (1.23e-1)" "unprognostic (4.27e-2)" "unprognostic (2.68e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.55e-6)" "unprognostic (2.61e-1)" "unprognostic (1.01e-1)" "unprognostic (1.75e-1)" "unprognostic (7.51e-2)" 7.9 3.0 0.0 0.0 0.3 0.0 9.8 0.1 1.5 12.0 0.1 83.5 0.0 5.5 0.9 7.3 22.5 0.0 2.3 0.0 0.2 7.2 7.0 33.4 0.0 0.6 0.2 22.0 1.3 0.4 0.9 0.3 0.3 3.8 2.2 0.0 82.1 0.0 0.3 2.8 54.2 0.3 0.1 283.3 48.0 0.3 0.1 0.0 19.3 0.0 0.0 278.5 4.0 1.4 3.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.5 2.6 3.2 0.0 0.0 1.4 0.0 4.1 0.0 0.3 0.0 0.6 3.7 0.0 0.1 8.8 0.4 1.8 0.0 0.8 5353.4 0.0 3.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.1 0.5 0.0 0.8 0.0 0.3 0.1 1.5 0.0 0.2 0.6 0.2 0.3 0.1 0.1 1.4 0.0 0.0 0.0 0.0 79.4 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 53.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15696.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 5.6 0.0 0.0 0.0 IGHV4-39 ENSG00000211959 "Immunoglobulin heavy variable 4-39" P01824 14 106421711-106422218 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 251.6;lymphoid tissue: 474.9;salivary gland: 247.1;urinary bladder: 541.3" "Cell type enriched" "Detected in some" 432 "Plasma cells: 48104.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.6;naive B-cell: 1.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 2.3;Daudi: 1.8;HL-60: 2.4;NB-4: 2.2;RH-30: 2.1;RPMI-8226: 1.4;U-266/70: 2.1;U-698: 2.0" "Immunoglobulin genes" NA NA 5000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.18e-3)" "unprognostic (2.99e-3)" "unprognostic (5.95e-3)" "unprognostic (1.46e-2)" "unprognostic (5.65e-2)" "unprognostic (2.38e-3)" "unprognostic (4.48e-2)" "unprognostic (2.63e-1)" "unprognostic (1.77e-1)" "unprognostic (2.23e-2)" "unprognostic (2.35e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (2.60e-6)" "unprognostic (2.04e-2)" "unprognostic (2.77e-1)" "unprognostic (7.68e-2)" "unprognostic (8.33e-2)" 17.8 6.5 0.5 378.0 0.5 14.5 33.2 0.1 0.8 24.0 1.5 251.6 4.4 12.5 2.5 19.1 17.7 0.0 11.4 0.1 0.2 13.8 13.8 54.9 0.0 0.8 1.2 17.6 3.7 1.2 1.4 0.0 0.6 7.1 5.0 0.0 247.1 9.5 0.5 12.1 143.6 2.0 0.1 474.9 108.1 1.3 0.4 2.8 37.2 0.0 5.3 541.3 13.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 2.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.3 0.0 0.0 1.1 2.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.6 0.0 0.2 0.2 0.0 2.1 0.0 2.0 0.0 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.2 1.6 0.1 0.1 0.1 1.7 0.5 0.1 1.1 0.1 0.1 0.2 0.1 0.0 0.5 0.5 0.1 0.8 0.1 0.2 0.8 1.2 0.6 0.1 0.4 0.3 0.0 0.0 0.0 0.0 89.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 111.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48104.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.3 0.0 0.3 0.0 IGHV4-4 ENSG00000276775 "Immunoglobulin heavy variable 4-4" A0A075B6R2 14 106011922-106012420 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 567.7;urinary bladder: 768.4" "Cell type enriched" "Detected in some" 285 "Plasma cells: 2624.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 10 "midbrain: 4.8" "Group enriched" "Detected in some" 23 "memory B-cell: 56.6;naive B-cell: 31.2" "Lineage enriched" "Detected in many" 30 "B-cells: 56.6" "Cell line enriched" "Detected in some" 18 "Karpas-707: 34.5" "Immunoglobulin genes" NA NA 3800000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.03e-3)" "unprognostic (1.93e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.60e-6)" "unprognostic (2.24e-1)" "unprognostic (6.27e-2)" "unprognostic (1.30e-1)" "unprognostic (2.10e-1)" "unprognostic (7.45e-2)" "prognostic unfavorable (1.69e-5)" "unprognostic (3.16e-1)" "unprognostic (2.59e-1)" "unprognostic (1.55e-1)" "unprognostic (2.05e-1)" 9.4 2.5 0.0 131.4 0.0 17.8 63.6 0.0 0.2 37.5 0.1 205.2 159.9 3.8 0.8 59.8 53.4 104.9 0.9 0.0 0.1 5.5 6.6 36.9 173.2 0.3 4.8 10.0 6.0 0.4 0.4 0.0 0.1 4.0 140.2 0.0 78.2 15.0 0.3 3.8 78.6 13.4 0.4 186.4 175.0 1.6 0.1 31.8 16.7 0.0 567.7 768.4 5.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.5 34.5 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.1 0.8 0.2 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 56.6 0.2 0.2 0.0 31.2 0.6 0.0 0.0 0.0 0.0 1.9 0.6 4.1 0.0 0.0 0.0 0.2 0.0 0.1 0.3 4.8 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2624.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 IGHV4-61 ENSG00000211970 "Immunoglobulin heavy variable 4-61" A0A0C4DH41 14 106639119-106639657 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 206.7;lymphoid tissue: 385.2;stomach 1: 143.1" "Cell type enriched" "Detected in some" 98 "Plasma cells: 2432.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 43 "memory B-cell: 39.0;naive B-cell: 25.5" "Lineage enriched" "Detected in single" 52 "B-cells: 39.0" "Cell line enriched" "Detected in single" 11 "MOLT-4: 8.7" "Immunoglobulin genes" NA NA 4400000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.11e-3)" "unprognostic (6.59e-2)" "unprognostic (4.92e-2)" "unprognostic (1.12e-2)" "prognostic favorable (3.71e-6)" "unprognostic (6.96e-2)" "unprognostic (5.98e-2)" "unprognostic (1.26e-1)" "unprognostic (1.72e-2)" "unprognostic (9.95e-2)" "unprognostic (9.02e-2)" "prognostic unfavorable (4.13e-6)" "unprognostic (3.55e-2)" "unprognostic (3.10e-1)" "unprognostic (4.24e-1)" "unprognostic (2.32e-2)" 6.4 44.4 0.0 97.5 0.1 30.8 56.0 0.0 0.2 10.1 0.1 206.7 185.7 5.8 0.0 15.5 5.0 22.4 3.1 0.0 0.1 5.5 10.5 28.2 54.4 0.3 0.1 10.4 1.3 0.2 0.7 0.0 0.3 4.1 121.8 0.0 104.3 7.0 0.2 0.7 86.5 8.0 0.3 181.3 143.1 0.9 0.0 30.1 23.0 0.0 385.2 43.9 5.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.4 0.0 0.0 8.7 0.8 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.4 0.5 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 39.0 0.0 0.1 0.0 25.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 4.6 0.0 0.1 0.0 0.2 0.0 0.1 0.3 0.1 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.8 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2432.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 IGHV5-51 ENSG00000211966 "Immunoglobulin heavy variable 5-51" A0A0C4DH38 14 106578744-106579236 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 245.7;lymphoid tissue: 547.1;salivary gland: 224.5;urinary bladder: 353.3" "Cell type enriched" "Detected in some" 87 "Plasma cells: 5993.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.8;Daudi: 3.7;K-562: 2.4;NB-4: 1.7;TIME: 3.3" HPA006014 Approved "Immunoglobulin genes" NA NA 2700000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA006014: " "unprognostic (2.03e-3)" "unprognostic (1.00e-1)" "unprognostic (3.21e-2)" "unprognostic (7.65e-3)" "unprognostic (1.80e-2)" "prognostic favorable (5.47e-4)" "unprognostic (2.40e-2)" "unprognostic (1.15e-1)" "unprognostic (3.92e-2)" "unprognostic (6.47e-2)" "unprognostic (2.49e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.31e-7)" "unprognostic (1.11e-1)" "unprognostic (1.05e-1)" "unprognostic (3.70e-1)" "unprognostic (1.17e-1)" 20.0 4.8 0.3 0.0 0.0 0.0 25.9 0.1 1.7 17.8 0.7 245.7 0.0 8.6 6.3 19.1 15.2 27.1 2.1 0.1 0.7 15.4 15.0 56.2 0.0 0.9 0.0 8.8 17.1 1.0 2.2 0.6 0.2 11.2 0.0 0.0 224.5 0.0 0.7 3.2 144.8 1.7 0.6 547.1 99.9 4.8 0.1 0.0 25.6 0.0 0.0 353.3 14.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 1.3 0.8 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.3 1.3 1.2 0.8 0.0 0.1 0.0 0.7 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.1 1.7 0.1 0.7 0.9 0.0 0.2 0.6 0.1 1.3 0.0 0.0 0.0 0.0 68.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.8 44.9 0.0 0.0 0.0 0.7 1.0 0.1 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5993.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 IGHV6-1 ENSG00000211933 "Immunoglobulin heavy variable 6-1" A0A0B4J1U7 14 105939756-105940253 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 441.3;lymphoid tissue: 159.0" "Cell type enriched" "Detected in some" 175 "Plasma cells: 2295.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "naive B-cell: 19.7" "Lineage enriched" "Detected in single" 53 "B-cells: 19.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 930000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.35e-4)" "unprognostic (9.66e-2)" "unprognostic (4.55e-3)" "unprognostic (1.26e-1)" "prognostic favorable (1.85e-5)" "unprognostic (1.84e-1)" "unprognostic (2.13e-2)" "unprognostic (1.89e-3)" "unprognostic (1.41e-1)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.48e-6)" "unprognostic (3.69e-2)" "unprognostic (6.93e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" 13.0 2.1 0.3 0.0 0.1 0.0 7.5 0.0 0.4 4.2 0.2 441.3 0.0 1.2 0.0 17.9 4.3 1.5 2.7 0.0 0.1 3.2 6.2 13.6 0.0 0.3 0.1 0.9 11.5 0.0 0.3 0.0 0.1 1.6 0.0 0.0 56.7 8.6 0.1 2.0 40.9 11.2 0.3 159.0 19.5 0.3 0.2 0.0 6.8 0.0 0.0 3.7 1.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.7 0.7 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 0.1 0.0 0.1 19.7 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.4 0.0 0.1 0.3 0.1 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 5.1 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2295.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 IGKV1-12 "IGKV112, L19" ENSG00000243290 "Immunoglobulin kappa variable 1-12" A0A0C4DH73 2 89040224-89040745 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 395.8;lymphoid tissue: 788.8" "Cell type enriched" "Detected in some" 92 "Plasma cells: 12442.9" "Cancer enhanced" "Detected in many" "stomach cancer: 17.2" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 820 "memory B-cell: 259.8;naive B-cell: 164.2" "Lineage enriched" "Detected in single" 1005 "B-cells: 259.8" "Cell line enhanced" "Detected in some" "BEWO: 1.5;Daudi: 2.1;RPMI-8226: 1.9;SH-SY5Y: 1.9" HPA048721 Approved "Immunoglobulin genes" NA NA 13000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (6.09e-4)" "prognostic favorable (1.59e-4)" "unprognostic (7.33e-2)" "unprognostic (3.74e-2)" "prognostic favorable (3.85e-5)" "unprognostic (5.89e-2)" "unprognostic (5.74e-1)" "unprognostic (7.13e-2)" "unprognostic (6.15e-2)" "unprognostic (3.90e-1)" "prognostic unfavorable (6.59e-8)" "unprognostic (1.18e-1)" "unprognostic (1.84e-1)" "unprognostic (2.68e-1)" "unprognostic (1.71e-1)" 13.6 144.8 0.0 201.7 0.2 73.1 116.8 0.0 0.4 50.8 0.2 395.8 240.6 7.3 0.0 57.1 16.2 69.6 9.9 0.1 0.1 13.7 17.8 65.3 238.6 0.6 0.0 18.1 7.2 0.2 1.4 0.0 1.1 7.2 278.6 0.0 219.0 5.4 0.4 2.8 231.2 11.2 1.2 360.5 254.9 6.7 0.0 69.5 32.7 0.0 788.8 243.3 9.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.0 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.0 259.8 0.0 0.1 0.1 164.2 0.0 0.1 0.2 0.1 0.1 0.1 0.1 24.3 0.0 0.2 0.0 0.4 0.1 0.1 0.6 0.0 1.1 1.2 0.0 0.3 0.0 0.0 0.0 0.0 134.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.2 1.3 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 20.4 0.0 0.0 0.0 1.8 1.6 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.3 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12442.9 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.3 0.0 0.3 5.0 0.0 0.0 0.0 IGKV1-16 "IGKV116, L1" ENSG00000240864 "Immunoglobulin kappa variable 1-16" P04430 2 89099859-89100361 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 279.7;lymphoid tissue: 597.8;urinary bladder: 260.3" "Cell type enriched" "Detected in some" 559 "Plasma cells: 18463.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 523 "memory B-cell: 164.7;naive B-cell: 112.8" "Lineage enriched" "Detected in single" 621 "B-cells: 164.7" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.0" HPA048721 Approved "Immunoglobulin genes" NA NA 10000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.63e-4)" "unprognostic (7.81e-2)" "unprognostic (1.43e-3)" "unprognostic (2.61e-2)" "unprognostic (3.22e-2)" "unprognostic (1.12e-3)" "unprognostic (1.69e-2)" "unprognostic (1.87e-1)" "unprognostic (8.35e-2)" "unprognostic (3.24e-2)" "unprognostic (1.30e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (2.84e-1)" "unprognostic (1.17e-1)" "unprognostic (3.84e-2)" "unprognostic (5.82e-2)" 11.8 4.7 0.1 159.1 0.1 40.0 75.9 0.0 0.8 76.0 0.6 279.7 199.4 6.3 0.5 34.3 6.6 99.0 11.4 0.0 0.1 9.2 14.9 40.5 155.0 0.2 0.0 17.7 2.0 0.1 3.6 0.1 0.1 5.6 235.6 0.0 126.9 30.9 0.8 0.7 143.6 11.8 0.1 315.4 158.9 2.0 0.1 45.7 18.4 0.0 597.8 260.3 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.1 0.2 1.0 0.0 0.0 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 164.7 0.0 0.0 0.1 112.8 0.0 0.1 0.2 0.0 0.0 0.0 0.0 16.9 0.1 0.1 0.0 0.8 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 33.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.6 21.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18463.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 IGKV1-17 "A30, IGKV117" ENSG00000240382 "Immunoglobulin kappa variable 1-17" P01599 2 89117342-89117844 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 375.0;lymphoid tissue: 454.4" "Cell type enriched" "Detected in some" 113 "Plasma cells: 4510.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 425 "memory B-cell: 105.7;naive B-cell: 82.2" "Lineage enriched" "Detected in single" 478 "B-cells: 105.7" "Cell line enhanced" "Detected in some" "Daudi: 1.9;K-562: 1.2;RPMI-8226: 2.0;SH-SY5Y: 1.4" HPA048721 Approved "Immunoglobulin genes" NA NA 8400000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (7.72e-3)" "unprognostic (1.60e-1)" "unprognostic (7.37e-3)" "unprognostic (1.78e-2)" "unprognostic (5.08e-3)" "prognostic favorable (4.11e-4)" "unprognostic (8.04e-2)" "unprognostic (1.00e-1)" "unprognostic (9.59e-2)" "unprognostic (1.76e-2)" "unprognostic (5.06e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (3.44e-7)" "unprognostic (3.12e-3)" "unprognostic (8.83e-2)" "unprognostic (3.80e-1)" "unprognostic (7.28e-2)" 12.8 26.5 0.1 183.7 0.2 27.7 87.1 0.0 0.7 11.9 0.4 358.5 294.8 6.6 4.1 54.7 12.4 55.7 10.9 0.0 0.1 10.3 14.2 36.5 95.7 0.6 0.0 12.4 3.3 1.1 1.0 0.1 0.2 5.5 375.0 0.0 134.3 31.0 1.3 1.2 152.7 4.7 0.1 306.1 159.7 2.4 0.3 45.6 25.8 0.0 454.4 182.6 6.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.8 2.0 0.0 0.0 0.5 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 105.7 0.0 0.0 0.1 82.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 12.6 0.1 0.2 0.0 0.7 0.0 0.1 0.6 0.0 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 39.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 11.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4510.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 IGKV1-27 "A20, IGKV127" ENSG00000244575 "Immunoglobulin kappa variable 1-27" A0A075B6S5 2 89213423-89213928 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 268.0;lymphoid tissue: 347.1;salivary gland: 177.6" "Cell type enriched" "Detected in some" 126 "Plasma cells: 4951.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 683 "memory B-cell: 152.7;naive B-cell: 185.3" "Lineage enriched" "Detected in single" 748 "B-cells: 185.3" "Cell line enhanced" "Detected in single" "BEWO: 1.8" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 8300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.56e-5)" "unprognostic (6.50e-3)" "unprognostic (2.65e-2)" "unprognostic (1.68e-3)" "unprognostic (1.72e-2)" "prognostic favorable (8.14e-4)" "unprognostic (9.60e-2)" "unprognostic (1.31e-1)" "unprognostic (2.41e-1)" "unprognostic (6.99e-3)" "unprognostic (9.31e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (8.84e-5)" "unprognostic (3.23e-2)" "unprognostic (1.34e-1)" "unprognostic (2.34e-1)" "unprognostic (2.67e-2)" 17.2 9.2 0.0 133.5 0.0 28.5 70.0 0.0 0.4 16.8 0.1 268.0 183.3 6.2 7.7 30.4 6.9 37.5 10.7 0.1 0.1 11.8 9.7 55.2 124.7 0.7 0.3 8.8 4.9 0.2 1.0 0.0 0.1 6.4 212.3 0.0 177.6 8.8 0.6 0.9 200.2 5.1 0.2 276.9 91.9 1.0 0.0 46.9 19.4 0.0 347.1 87.7 6.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.4 0.6 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.7 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.1 0.1 152.7 0.1 0.1 0.1 185.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 15.8 0.0 0.0 0.0 0.4 0.1 0.1 0.7 0.3 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 39.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.3 12.2 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4951.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 IGKV1-33 "IGKV133, O18" ENSG00000242076 "Immunoglobulin kappa variable 1-33" P01594 2 89266494-89268506 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1727.5;stomach 1: 627.3;urinary bladder: 623.3" "Cell type enriched" "Detected in some" 131 "Plasma cells: 2044.1" "Cancer enhanced" "Detected in many" "stomach cancer: 5.5" "Region enriched" "Detected in many" 7 "spinal cord: 12.0" "Group enriched" "Detected in some" 378 "memory B-cell: 369.6;naive B-cell: 441.5" "Lineage enriched" "Detected in many" 411 "B-cells: 441.5" "Cell line enhanced" "Detected in some" "RPMI-8226: 2.7;SCLC-21H: 9.1;SH-SY5Y: 8.8;U-251 MG: 3.5" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (1.76e-2)" "unprognostic (6.79e-2)" "unprognostic (1.52e-2)" "prognostic favorable (4.58e-5)" "unprognostic (5.06e-2)" "unprognostic (8.55e-3)" "unprognostic (2.31e-1)" "unprognostic (1.63e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-1)" 50.5 21.9 0.1 266.2 0.5 139.5 320.5 0.6 1.0 129.8 0.4 471.5 296.2 20.7 2.8 106.2 33.4 187.2 23.2 0.2 1.6 36.7 37.9 130.4 529.5 0.4 1.0 37.0 8.3 1.9 2.7 0.4 0.7 18.7 511.9 0.2 476.4 127.7 0.7 2.5 175.9 14.5 12.0 820.8 627.3 13.5 0.2 381.9 53.9 0.2 1727.5 623.3 26.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.1 1.9 2.7 0.0 0.0 9.1 8.8 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.4 3.5 0.7 0.0 0.2 0.0 0.6 0.0 0.4 0.3 0.4 0.1 0.0 0.1 369.6 0.2 0.1 0.3 441.5 0.2 0.1 1.0 0.2 0.3 0.3 0.2 39.5 0.1 0.5 0.6 1.0 0.2 1.6 0.4 1.0 0.7 12.0 0.2 1.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2044.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 IGKV1-39 ENSG00000242371 "Immunoglobulin kappa variable 1-39" P01597 2 89319625-89320146 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 108.5;lymphoid tissue: 254.9;salivary gland: 151.2;stomach 1: 83.2" "Cell type enriched" "Detected in some" 151 "Plasma cells: 16225.1" "Cancer enhanced" "Detected in many" "stomach cancer: 13.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 388 "memory B-cell: 1069.8;naive B-cell: 935.1" "Lineage enriched" "Detected in many" 415 "B-cells: 1069.8" "Cell line enriched" "Detected in some" 21 "Daudi: 194.2" HPA048721 Approved "Immunoglobulin genes" NA NA 8000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.76e-4)" "unprognostic (5.10e-3)" "unprognostic (4.71e-2)" "prognostic favorable (1.70e-5)" "unprognostic (2.38e-1)" "unprognostic (7.33e-2)" "unprognostic (1.78e-1)" "unprognostic (6.62e-6)" "unprognostic (1.19e-1)" "unprognostic (1.28e-1)" "unprognostic (4.27e-1)" "unprognostic (2.25e-1)" 10.9 9.1 0.0 54.7 0.1 14.2 17.7 0.0 0.1 21.8 0.0 108.5 70.5 5.7 0.0 11.6 12.5 14.3 1.5 0.2 0.0 10.9 6.8 27.2 36.5 0.0 0.0 1.8 3.2 0.0 0.5 0.0 0.2 4.2 13.3 0.0 151.2 0.9 0.2 1.3 74.4 1.2 0.0 254.9 83.2 0.3 0.0 5.9 31.0 0.0 42.5 17.5 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 194.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 1.8 0.0 9.0 0.0 0.0 0.0 0.9 1.0 0.7 0.3 0.3 0.3 1069.8 0.5 0.4 1.1 935.1 0.3 0.6 2.5 0.4 0.6 1.3 0.8 136.4 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 10.7 0.0 0.0 0.0 0.4 3.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16225.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 4.9 0.0 0.3 0.0 IGKV1-6 ENSG00000239855 "Immunoglobulin kappa variable 1-6" A0A0C4DH72 2 88966262-88966767 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 155.5;lymphoid tissue: 606.3" "Cell type enriched" "Detected in some" 33 "Plasma cells: 877.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 801 "memory B-cell: 123.6;naive B-cell: 85.7" "Lineage enriched" "Detected in single" 946 "B-cells: 123.6" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 12000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (3.44e-5)" "unprognostic (5.25e-3)" "unprognostic (3.78e-2)" "unprognostic (8.68e-3)" "unprognostic (3.23e-2)" "prognostic favorable (1.81e-4)" "unprognostic (3.86e-3)" "unprognostic (3.86e-2)" "unprognostic (3.00e-2)" "unprognostic (5.80e-2)" "unprognostic (1.90e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (4.37e-6)" "unprognostic (5.23e-3)" "unprognostic (3.02e-1)" "unprognostic (2.54e-1)" "unprognostic (2.54e-1)" 8.2 1.7 0.1 84.1 0.1 37.0 50.3 0.0 0.4 16.5 0.1 155.5 110.5 4.0 4.1 23.5 5.0 18.1 5.3 0.0 0.0 7.7 6.3 20.0 82.3 0.1 0.1 4.0 1.8 0.0 1.1 0.0 0.0 4.3 145.9 0.0 95.0 2.2 0.2 0.6 59.1 5.1 0.2 209.5 130.3 0.7 0.0 22.7 16.4 0.0 606.3 144.8 8.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 123.6 0.0 0.0 0.1 85.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 14.1 0.1 0.1 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 877.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 IGKV1-8 "IGKV18, L9" ENSG00000240671 "Immunoglobulin kappa variable 1-8" A0A0C4DH67 2 88992409-88992931 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 29.7;lymphoid tissue: 55.0;salivary gland: 21.2;stomach 1: 18.6;urinary bladder: 41.7" "Cell type enriched" "Detected in some" 40 "Plasma cells: 622.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 311 "memory B-cell: 131.0;naive B-cell: 136.4" "Lineage enriched" "Detected in single" 317 "B-cells: 136.4" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 6100000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.64e-4)" "unprognostic (1.56e-2)" "unprognostic (8.07e-2)" "unprognostic (6.41e-3)" "prognostic favorable (5.13e-4)" "unprognostic (6.87e-2)" "unprognostic (2.91e-2)" "unprognostic (3.36e-2)" "unprognostic (2.79e-2)" "unprognostic (1.75e-1)" "unprognostic (7.79e-2)" "prognostic unfavorable (4.14e-7)" "unprognostic (6.94e-2)" "unprognostic (1.34e-1)" "unprognostic (4.22e-2)" "unprognostic (2.98e-1)" 2.1 2.5 0.0 13.5 0.0 7.1 6.7 0.0 0.1 2.0 0.0 29.7 12.0 1.3 0.0 2.9 1.4 5.4 1.5 0.0 0.0 3.3 2.1 4.8 13.7 0.0 0.0 0.5 0.9 0.0 0.1 0.0 0.0 1.4 19.3 0.0 21.2 0.7 0.0 0.1 13.9 0.6 0.0 51.3 18.6 0.3 0.0 7.0 3.3 0.0 55.0 41.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 131.0 0.0 0.4 0.1 136.4 0.1 0.0 0.1 0.1 0.1 0.0 0.1 12.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 622.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 IGKV1-9 "IGKV19, L8" ENSG00000241755 "Immunoglobulin kappa variable 1-9" A0A0C4DH69 2 89009982-89010515 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 428.1;lymphoid tissue: 671.3;stomach 1: 283.7" "Cell type enriched" "Detected in some" 116 "Plasma cells: 7178.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 705 "memory B-cell: 300.5;naive B-cell: 296.8" "Lineage enriched" "Detected in single" 709 "B-cells: 300.5" "Cell line enhanced" "Detected in some" "HL-60: 1.2;NB-4: 1.0;RPMI-8226: 2.9;TIME: 1.2" HPA048721 Approved "Immunoglobulin genes" NA NA 4500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.10e-7)" "unprognostic (1.30e-2)" "unprognostic (1.95e-2)" "unprognostic (2.55e-3)" "unprognostic (4.70e-2)" "prognostic favorable (4.91e-4)" "unprognostic (3.30e-2)" "unprognostic (1.57e-1)" "unprognostic (1.09e-2)" "unprognostic (6.80e-2)" "unprognostic (1.95e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (6.04e-8)" "unprognostic (4.03e-2)" "unprognostic (1.08e-1)" "unprognostic (1.47e-1)" "unprognostic (3.40e-1)" 12.6 12.6 0.2 184.3 0.4 53.6 202.8 0.0 1.3 15.8 0.4 428.1 267.0 8.3 0.8 52.9 78.3 30.0 13.9 0.1 0.1 15.4 17.9 40.1 201.8 0.3 0.1 20.7 2.5 0.5 1.3 0.1 0.2 12.8 348.6 0.0 221.3 13.3 0.5 1.6 182.8 13.3 0.4 313.1 283.7 35.1 0.1 85.1 34.2 0.0 671.3 187.5 8.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 1.0 0.3 0.0 0.0 0.0 0.9 2.9 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.1 0.0 0.5 0.0 0.2 0.0 0.2 0.0 0.2 0.4 0.1 0.2 0.0 0.1 300.5 0.1 0.0 0.3 296.8 0.0 0.1 0.3 0.2 0.2 0.1 0.3 34.5 0.2 0.4 0.0 1.3 0.1 0.1 0.3 0.1 0.2 0.4 0.1 0.3 0.0 0.0 0.0 0.0 61.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 10.7 0.0 0.0 0.0 1.8 0.7 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7178.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 IGKV1D-33 ENSG00000239975 "Immunoglobulin kappa variable 1D-33" P01593 2 89913982-89916052 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.7;lymphoid tissue: 63.0;salivary gland: 73.3" "Cell type enriched" "Detected in some" 410 "Plasma cells: 5131.4" "Cancer enhanced" "Detected in many" "stomach cancer: 5.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 116 "memory B-cell: 6.3;naive B-cell: 16.8" "Lineage enriched" "Detected in single" 169 "B-cells: 16.8" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 4900000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (5.10e-3)" "unprognostic (2.03e-1)" "unprognostic (2.11e-2)" "unprognostic (2.03e-4)" "unprognostic (7.90e-2)" "unprognostic (6.50e-2)" "unprognostic (6.82e-2)" "unprognostic (4.54e-2)" "unprognostic (4.23e-2)" 2.8 0.5 0.0 3.8 0.1 2.3 8.3 0.0 0.1 3.6 0.1 32.7 1.3 1.4 0.0 4.6 2.7 2.6 0.2 0.2 0.2 4.0 2.2 17.9 6.8 0.0 0.2 0.4 0.5 0.0 0.1 0.0 0.0 1.6 2.0 0.0 73.3 8.6 0.0 0.5 19.1 0.0 0.5 63.0 21.2 0.1 0.0 4.7 3.3 0.2 9.1 16.8 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5131.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 IGKV1D-39 ENSG00000251546 "Immunoglobulin kappa variable 1D-39" P04432 2 89862482-89862981 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2922.1;lymphoid tissue: 6491.8;stomach 1: 2259.8" "Cell type enriched" "Detected in some" 298 "Plasma cells: 7890.2" "Cancer enhanced" "Detected in many" "stomach cancer: 12.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 226 "memory B-cell: 470.5;naive B-cell: 733.0" "Lineage enriched" "Detected in many" 275 "B-cells: 733.0" "Group enriched" "Detected in some" 36 "Daudi: 731.4;U-698: 516.7" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.88e-4)" "unprognostic (4.70e-2)" "unprognostic (2.14e-3)" "prognostic favorable (5.99e-5)" "unprognostic (3.84e-1)" "unprognostic (4.34e-2)" "unprognostic (1.28e-1)" "unprognostic (9.06e-2)" "unprognostic (2.96e-2)" "unprognostic (3.92e-1)" "unprognostic (1.84e-1)" 147.3 181.1 0.6 1609.8 0.8 466.1 990.4 0.5 4.2 369.0 2.1 2922.1 2055.2 80.0 52.5 611.3 132.1 629.8 87.5 0.4 2.0 82.3 171.8 685.1 1968.9 2.6 0.8 214.9 26.5 3.5 5.5 1.3 3.6 80.9 2261.1 0.4 1229.7 148.4 2.3 33.2 1255.9 88.7 4.2 1712.0 2259.8 27.6 1.3 770.5 209.3 0.0 6491.8 1816.1 46.9 2.5 0.3 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 731.4 0.5 0.0 0.0 2.1 0.0 0.0 0.0 0.3 0.0 3.2 0.0 0.0 0.0 5.9 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 2.3 6.6 2.4 0.0 0.0 1.0 2.9 10.3 0.0 0.0 11.1 17.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.8 2.5 0.0 0.1 516.7 0.0 1.6 0.0 0.5 0.4 0.8 0.6 0.2 0.4 470.5 0.3 0.3 0.4 733.0 0.5 0.2 2.6 0.8 0.4 0.4 0.3 47.6 0.6 0.8 0.5 4.2 0.4 2.0 2.6 0.8 3.6 4.2 1.3 2.5 0.0 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7890.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 14.0 0.0 0.0 0.0 IGKV2-24 ENSG00000241294 "Immunoglobulin kappa variable 2-24" A0A0C4DH68 2 89176328-89177160 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 272.7;lymphoid tissue: 474.9;urinary bladder: 935.2" "Cell type enriched" "Detected in some" 252 "Plasma cells: 5620.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 4 "memory B-cell: 48.1" "Lineage enriched" "Detected in single" 482 "B-cells: 48.1" "Cell line enhanced" "Detected in single" "NB-4: 1.3" "Immunoglobulin genes" NA NA 840000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.74e-6)" "unprognostic (4.92e-3)" "unprognostic (1.04e-2)" "unprognostic (2.38e-2)" "unprognostic (3.79e-3)" "prognostic favorable (1.59e-4)" "unprognostic (5.02e-2)" "unprognostic (1.65e-1)" "unprognostic (2.71e-2)" "unprognostic (1.31e-1)" "unprognostic (4.10e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.82e-5)" "unprognostic (1.03e-1)" "unprognostic (1.53e-1)" "unprognostic (1.08e-1)" "unprognostic (1.65e-1)" 13.7 14.6 0.1 65.8 0.1 27.4 91.8 0.0 0.6 11.5 0.4 272.7 250.8 3.2 1.1 82.0 6.6 24.1 14.7 0.2 1.0 7.8 8.6 30.0 131.7 0.6 0.1 6.3 5.6 0.2 0.9 0.2 0.9 5.4 180.6 0.0 219.3 3.3 0.3 3.3 98.5 7.9 1.1 474.9 106.8 1.2 0.2 23.7 11.1 0.0 235.6 935.2 14.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.1 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.1 0.0 0.6 0.2 1.0 0.6 0.1 0.9 1.1 0.2 0.3 0.0 0.0 0.0 0.0 22.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 3.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5620.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGKV2-30 ENSG00000243238 "Immunoglobulin kappa variable 2-30" P06310 2 89244781-89245596 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 631.0;lymphoid tissue: 670.2;stomach 1: 323.1" "Cell type enriched" "Detected in some" 365 "Plasma cells: 25365.6" "Cancer enhanced" "Detected in many" "stomach cancer: 26.0" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 316 "memory B-cell: 561.0;naive B-cell: 325.4" "Lineage enriched" "Detected in many" 400 "B-cells: 561.0" "Cell line enriched" "Detected in some" 388 "U-698: 8426.0" "Immunoglobulin genes" NA NA 6800000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.84e-5)" "unprognostic (1.26e-2)" "unprognostic (2.88e-2)" "unprognostic (1.41e-1)" "prognostic favorable (6.78e-5)" "unprognostic (6.92e-2)" "unprognostic (1.20e-2)" "unprognostic (1.45e-2)" "unprognostic (9.82e-3)" "unprognostic (1.84e-1)" "unprognostic (3.07e-1)" "prognostic unfavorable (4.53e-6)" "unprognostic (1.74e-1)" "unprognostic (1.23e-1)" "unprognostic (1.53e-1)" "unprognostic (3.50e-1)" 15.0 9.4 0.1 160.7 0.2 75.9 237.0 0.1 1.3 19.6 0.7 631.0 394.3 5.6 0.8 37.8 11.5 35.0 17.9 0.1 0.1 15.1 29.6 67.3 176.7 1.4 0.1 15.8 7.8 0.1 2.3 0.2 0.2 7.8 324.5 0.0 220.5 23.3 0.6 2.0 260.2 19.1 0.6 670.2 323.1 21.2 0.1 40.9 18.8 0.0 600.3 207.5 21.5 1.1 5.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 13.1 4.6 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 1.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.8 0.3 0.0 0.0 0.1 2.7 1.9 0.0 0.4 0.0 0.9 3.8 0.0 2.6 0.0 0.0 5.6 0.0 0.0 21.7 0.1 2.6 0.3 1.7 8426.0 0.0 2.7 0.0 0.5 0.4 0.2 0.2 0.0 0.2 561.0 0.1 0.2 0.4 325.4 0.0 0.2 1.4 0.2 0.3 0.7 0.3 53.3 0.1 0.2 0.1 1.3 0.1 0.1 1.4 0.1 0.2 0.6 0.1 1.1 0.0 0.0 0.0 0.0 69.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 30.5 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25365.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.2 0.0 0.3 0.0 IGKV2-40 ENSG00000273962 "Immunoglobulin kappa variable 2-40" A0A087WW87 2 89330110-89330429 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 42.8;urinary bladder: 34.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 48 "memory B-cell: 15.4;naive B-cell: 7.1" "Lineage enriched" "Detected in single" 66 "B-cells: 15.4" "Cell line enhanced" "Detected in single" "Daudi: 1.7" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "unprognostic (3.31e-1)" "unprognostic (1.94e-2)" 0.4 0.1 0.0 9.3 0.0 1.1 6.7 0.0 0.1 10.2 0.0 9.7 42.8 0.9 0.0 10.5 15.5 0.1 0.1 0.0 0.0 0.3 1.4 10.9 0.9 0.0 0.0 3.2 0.0 0.0 0.1 0.0 0.0 1.1 7.1 0.0 5.9 2.0 0.0 0.1 6.2 0.0 0.0 17.8 19.6 0.2 0.0 1.9 1.2 0.1 6.2 34.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV2D-29 ENSG00000243264 "Immunoglobulin kappa variable 2D-29" A0A075B6S2 2 89947512-89948279 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 252.2;lymphoid tissue: 464.7" "Cell type enriched" "Detected in some" 8 "Plasma cells: 184.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 253 "memory B-cell: 360.5;naive B-cell: 489.4" "Lineage enriched" "Detected in many" 292 "B-cells: 489.4" "Cell line enhanced" "Detected in some" "Daudi: 8.5;HDLM-2: 1.2;TIME: 2.1;U-698: 2.2" "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.31e-4)" "unprognostic (2.43e-2)" "unprognostic (1.34e-3)" "unprognostic (1.76e-2)" "prognostic favorable (8.34e-4)" "unprognostic (4.43e-3)" "unprognostic (1.54e-1)" "unprognostic (2.34e-1)" "unprognostic (2.47e-2)" "unprognostic (5.09e-2)" "unprognostic (8.87e-2)" "prognostic unfavorable (2.97e-4)" "unprognostic (9.46e-2)" "unprognostic (2.20e-1)" "unprognostic (2.61e-1)" "unprognostic (7.80e-2)" 11.3 1.0 0.0 73.7 0.1 29.4 49.4 0.1 1.3 12.6 0.8 252.2 97.0 3.9 0.0 9.5 6.5 14.2 3.8 0.1 0.2 3.6 8.4 41.4 139.4 0.3 0.0 9.8 2.8 0.2 0.3 0.0 0.2 3.6 110.9 0.0 106.8 10.3 0.4 3.0 67.9 2.9 0.4 170.2 126.0 1.0 0.1 38.0 7.8 0.0 464.7 35.1 2.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.2 0.7 0.3 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.1 0.2 0.1 0.0 2.2 0.0 0.1 0.0 0.3 0.4 0.2 0.1 0.0 0.2 360.5 0.2 0.1 0.6 489.4 0.0 0.1 1.6 0.2 0.4 0.2 0.2 42.2 0.0 0.1 0.1 1.3 0.1 0.2 0.3 0.0 0.2 0.4 0.1 0.2 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 184.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 IGKV3-15 ENSG00000244437 "Immunoglobulin kappa variable 3-15" P01624 2 89085177-89085787 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 785.8;lymphoid tissue: 1996.3;urinary bladder: 784.8" "Cell type enriched" "Detected in some" 85 "Plasma cells: 22923.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 561 "memory B-cell: 2243.8;naive B-cell: 1651.4" "Lineage enriched" "Detected in all" 646 "B-cells: 2243.8" "Cell line enhanced" "Detected in some" "Daudi: 1.7;K-562: 1.3;NB-4: 1.9;RH-30: 1.2;RPMI-8226: 2.2;SCLC-21H: 1.4;SH-SY5Y: 2.5" HPA047702 Approved "Immunoglobulin genes" NA NA 7200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.57e-4)" "unprognostic (1.29e-2)" "unprognostic (7.02e-3)" "unprognostic (3.89e-3)" "unprognostic (9.06e-3)" "unprognostic (2.06e-3)" "unprognostic (5.36e-2)" "unprognostic (3.55e-1)" "unprognostic (1.45e-1)" "unprognostic (5.82e-3)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (3.15e-7)" "unprognostic (2.00e-1)" "unprognostic (2.54e-1)" "unprognostic (2.07e-1)" "unprognostic (1.17e-1)" 47.9 114.5 0.0 603.8 0.1 131.0 174.3 0.0 1.5 141.8 0.3 785.8 431.4 19.4 34.7 120.0 30.0 144.4 14.8 0.1 0.3 35.2 36.7 184.8 500.9 0.7 0.3 55.4 9.3 2.5 3.0 0.5 0.3 18.3 649.4 0.0 399.3 114.2 1.0 2.7 335.8 29.5 1.5 1020.7 629.8 64.8 0.2 250.2 77.7 0.0 1996.3 784.8 28.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.4 1.9 0.6 0.0 0.0 0.0 1.2 2.2 0.0 0.0 1.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.4 0.7 0.5 0.0 0.0 0.0 1.0 0.0 1.8 3.4 0.8 1.0 0.4 0.8 2243.8 1.0 1.1 1.8 1651.4 1.0 1.1 1.9 1.0 1.3 1.7 1.5 193.1 0.0 0.1 0.0 1.5 0.1 0.3 0.7 0.3 0.3 1.5 0.2 1.0 0.0 0.0 0.0 0.0 269.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 2.6 73.4 0.0 0.0 0.0 1.4 1.1 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 22923.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 252.5 0.0 0.0 0.2 0.0 0.0 28.2 0.0 0.0 0.0 IGKV3-7 ENSG00000243063 "Immunoglobulin kappa variable 3-7 (non-functional)" A0A075B6H7 2 88978468-88979081 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.6;lymphoid tissue: 22.2;salivary gland: 15.9;stomach 1: 10.2" "Group enriched" "Detected in some" 37 "B-cells: 1.5;Plasma cells: 5.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 61 "memory B-cell: 27.8;naive B-cell: 24.3" "Lineage enriched" "Detected in single" 65 "B-cells: 27.8" "Not detected" "Not detected" HPA047702 Approved "Immunoglobulin genes" NA NA 850000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.17e-4)" "unprognostic (3.07e-3)" "unprognostic (3.96e-2)" "unprognostic (1.28e-2)" "unprognostic (1.20e-3)" "unprognostic (1.19e-1)" "unprognostic (5.91e-2)" "unprognostic (2.73e-1)" "unprognostic (4.24e-2)" "unprognostic (2.15e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (1.27e-5)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (4.46e-2)" "unprognostic (2.64e-2)" 0.3 0.4 0.0 15.0 0.0 4.2 3.9 0.0 0.0 2.1 0.0 18.6 15.1 0.3 0.1 1.5 0.1 1.3 0.0 0.0 0.0 0.2 0.5 1.8 2.5 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 13.6 0.0 15.9 0.1 0.0 0.0 11.2 0.7 0.0 4.9 10.2 0.0 0.0 1.4 0.1 0.0 22.2 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.8 0.0 0.0 0.0 24.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV3D-11 ENSG00000211632 "Immunoglobulin kappa variable 3D-11" A0A0A0MRZ8 2 90172802-90173414 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 38.6;lymphoid tissue: 58.5;stomach 1: 27.7" "Cell type enriched" "Detected in some" 34 "Plasma cells: 196.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 468 "memory B-cell: 152.5;naive B-cell: 146.1" "Lineage enriched" "Detected in single" 478 "B-cells: 152.5" "Cell line enhanced" "Detected in single" "U-266/70: 2.1" HPA047702 Approved "Immunoglobulin genes" NA NA 6700000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.40e-5)" "unprognostic (7.90e-3)" "unprognostic (1.91e-2)" "unprognostic (2.24e-3)" "prognostic favorable (5.58e-5)" "unprognostic (2.65e-2)" "unprognostic (2.13e-1)" "unprognostic (2.78e-1)" "unprognostic (6.31e-2)" "unprognostic (3.49e-1)" "unprognostic (3.61e-1)" "prognostic unfavorable (2.20e-6)" "unprognostic (1.12e-1)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "unprognostic (1.24e-2)" 1.3 0.7 0.3 35.9 0.2 8.9 6.4 0.0 0.1 1.7 0.0 38.6 32.2 0.8 0.0 2.4 2.1 2.7 0.5 0.0 0.1 2.1 1.3 12.4 13.0 0.1 0.3 1.5 0.5 0.0 0.1 0.0 0.1 0.7 26.6 0.0 18.8 0.3 0.0 0.1 23.6 0.7 0.2 29.9 27.7 0.2 0.0 4.2 2.3 0.0 58.5 17.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.8 0.4 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 152.5 0.0 0.0 0.1 146.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 30.2 0.3 0.2 0.0 0.1 0.0 0.1 0.1 0.3 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 196.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 IGKV3D-15 ENSG00000224041 "Immunoglobulin kappa variable 3D-15" A0A087WSY6 2 90114838-90115402 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 126.7;lymphoid tissue: 203.0;salivary gland: 54.1;stomach 1: 87.4;urinary bladder: 58.0" "Cell type enriched" "Detected in some" 622 "Plasma cells: 3673.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 191 "memory B-cell: 181.1;naive B-cell: 155.6" "Lineage enriched" "Detected in single" 206 "B-cells: 181.1" "Cell line enhanced" "Detected in some" "HaCaT: 1.0;HL-60: 2.6;SiHa: 1.7" HPA047702 Approved "Immunoglobulin genes" NA NA 4800000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.11e-4)" "prognostic favorable (7.46e-4)" "unprognostic (9.16e-3)" "unprognostic (1.74e-1)" "unprognostic (1.90e-3)" "unprognostic (7.20e-2)" "unprognostic (9.19e-2)" "unprognostic (4.93e-1)" "unprognostic (3.42e-2)" "unprognostic (1.41e-1)" "unprognostic (2.97e-1)" "prognostic unfavorable (1.82e-6)" "unprognostic (8.99e-2)" "unprognostic (2.62e-1)" "unprognostic (1.21e-1)" "unprognostic (2.04e-1)" 3.1 4.4 0.1 93.5 0.4 11.1 17.1 0.1 0.5 5.9 0.3 111.6 63.0 1.0 0.0 16.4 5.2 10.1 2.3 0.1 0.2 3.6 2.0 18.0 43.6 0.4 0.2 17.9 4.0 0.3 0.1 0.0 0.2 1.7 126.7 0.0 54.1 1.1 0.1 0.6 46.7 4.3 0.3 56.3 87.4 0.2 0.1 13.0 4.5 0.0 203.0 58.0 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.3 1.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.6 0.0 0.6 0.0 0.1 0.8 0.0 0.0 0.0 0.0 181.1 0.0 0.0 0.1 155.6 0.0 0.0 0.0 0.1 0.1 0.0 0.1 27.5 0.1 0.4 0.1 0.5 0.1 0.2 0.4 0.2 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3673.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGKV3D-20 ENSG00000211625 "Immunoglobulin kappa variable 3D-20" A0A0C4DH25 2 90038848-90039479 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 131.8;lymphoid tissue: 275.4" "Cell type enriched" "Detected in some" 38 "Plasma cells: 289.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 1042 "memory B-cell: 197.3;naive B-cell: 99.0" "Lineage enriched" "Detected in single" 1388 "B-cells: 197.3" "Cell line enriched" "Detected in some" 4 "U-266/70: 19.5" HPA047702 Approved "Immunoglobulin genes" NA NA 11000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.82e-4)" "unprognostic (4.70e-3)" "unprognostic (3.16e-2)" "unprognostic (8.10e-3)" "unprognostic (2.05e-1)" "unprognostic (2.60e-3)" "unprognostic (3.37e-1)" "unprognostic (1.68e-1)" "unprognostic (5.15e-2)" "unprognostic (2.53e-2)" "unprognostic (2.29e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (3.56e-6)" "unprognostic (7.10e-2)" "unprognostic (2.05e-1)" "unprognostic (1.84e-1)" "unprognostic (1.73e-1)" 4.0 6.3 0.0 81.2 0.0 16.0 32.4 0.0 0.6 12.2 0.1 131.8 55.9 2.7 0.0 15.3 4.2 16.2 6.4 0.0 0.1 3.0 6.4 20.6 73.5 0.2 0.1 7.1 3.3 0.0 0.3 0.1 0.1 3.7 88.1 0.0 64.0 3.3 0.1 2.6 77.7 6.0 0.3 88.4 82.5 1.2 0.0 16.2 5.2 0.0 275.4 38.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 19.5 4.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 197.3 0.0 0.1 0.1 99.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 34.1 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 289.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 IGKV4-1 "B3, IGKV41" ENSG00000211598 "Immunoglobulin kappa variable 4-1" P06312 2 88885397-88886153 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1805.7;lymphoid tissue: 3169.0" "Cell type enriched" "Detected in some" 219 "Plasma cells: 46306.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 588 "memory B-cell: 3036.3;naive B-cell: 3070.9" "Lineage enriched" "Detected in all" 591 "B-cells: 3070.9" "Cell line enhanced" "Detected in some" "Daudi: 14.9;RPMI-8226: 10.4;SH-SY5Y: 6.9;U-266/70: 7.5" "Immunoglobulin genes" NA NA 8500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.41e-5)" "unprognostic (9.19e-2)" "unprognostic (4.29e-3)" "unprognostic (5.42e-3)" "unprognostic (2.08e-2)" "prognostic favorable (8.25e-4)" "unprognostic (1.79e-2)" "unprognostic (1.12e-1)" "unprognostic (3.32e-1)" "unprognostic (3.71e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-1)" "prognostic unfavorable (2.52e-6)" "unprognostic (1.99e-1)" "unprognostic (1.01e-1)" "unprognostic (6.29e-2)" "unprognostic (1.19e-1)" 55.9 296.3 0.4 1054.1 0.9 342.1 665.2 0.4 3.4 145.2 2.4 1805.7 1769.7 46.8 19.4 195.7 41.3 188.2 51.9 0.4 1.2 35.0 76.1 302.3 816.8 1.9 0.8 86.5 28.3 2.5 2.8 1.0 3.5 43.9 1318.2 0.1 701.8 89.6 1.0 8.6 1023.0 66.4 3.6 972.3 1125.7 125.7 0.7 405.1 51.0 0.1 3169.0 758.2 19.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.9 0.0 1.7 0.0 0.0 0.0 3.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.6 3.6 0.3 0.0 0.0 1.4 2.2 10.4 0.0 0.0 4.0 6.9 2.3 0.0 0.0 0.0 0.0 0.7 2.6 0.0 0.8 1.1 1.0 7.5 0.2 0.8 0.0 1.2 0.0 3.9 3.2 5.1 1.6 0.9 1.7 3036.3 1.9 1.1 2.8 3070.9 2.1 1.3 2.4 1.6 2.4 2.3 1.7 344.9 0.4 0.9 0.4 3.4 0.4 1.2 1.9 0.8 3.5 3.6 0.7 1.5 0.0 0.0 0.0 0.0 210.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 8.0 0.0 0.0 0.0 17.0 40.2 0.0 0.0 0.0 2.2 2.8 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 46306.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 15.7 0.0 0.1 0.0 IGKV6-21 "A26, IGKV621" ENSG00000211611 "Immunoglobulin kappa variable 6-21 (non-functional)" A0A0C4DH24 2 89159751-89160366 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 97.3;lymphoid tissue: 141.0" "Cell type enriched" "Detected in some" 142 "Plasma cells: 1715.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 194 "memory B-cell: 28.8;naive B-cell: 9.8" "Lineage enriched" "Detected in single" 289 "B-cells: 28.8" "Cell line enriched" "Detected in some" 6 "U-266/70: 10.5" "Immunoglobulin genes" NA NA 250000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.82e-4)" "unprognostic (1.80e-2)" "unprognostic (4.99e-3)" "unprognostic (2.32e-2)" "unprognostic (1.51e-3)" "unprognostic (1.93e-1)" "unprognostic (6.32e-2)" "unprognostic (4.74e-2)" "unprognostic (8.91e-2)" "unprognostic (7.31e-2)" "prognostic unfavorable (5.05e-4)" "unprognostic (1.45e-1)" "unprognostic (2.38e-1)" "unprognostic (2.41e-1)" "unprognostic (2.14e-1)" 2.2 0.4 0.0 41.6 0.0 12.0 37.4 0.0 0.1 3.3 0.0 97.3 38.8 1.8 0.6 8.4 1.9 5.9 0.5 0.0 0.0 2.7 2.6 11.9 64.4 0.2 0.0 2.1 0.8 0.0 0.1 0.0 0.0 1.5 79.3 0.0 43.5 9.0 0.0 0.5 38.5 5.0 0.1 63.8 36.3 0.9 0.0 10.2 3.5 0.0 141.0 37.4 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 1.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 6.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1715.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGLC7 ENSG00000211685 "Immunoglobulin lambda constant 7" 22 22922594-22923034 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 88.1;lymphoid tissue: 107.7;salivary gland: 70.1;stomach 1: 113.1" "Cell type enriched" "Detected in some" 10 "B-cells: 109.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 341 "memory B-cell: 128.8;naive B-cell: 133.0" "Lineage enriched" "Detected in single" 346 "B-cells: 133.0" "Cell line enriched" "Detected in some" 913 "Karpas-707: 122629.0" "Immunoglobulin genes" NA NA "Cluster 37: B-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.20e-3)" "unprognostic (5.94e-2)" "unprognostic (3.91e-1)" "unprognostic (2.16e-2)" "prognostic favorable (2.03e-4)" "unprognostic (2.11e-1)" "unprognostic (9.60e-3)" "unprognostic (2.47e-2)" "unprognostic (1.88e-1)" "unprognostic (2.74e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (1.61e-6)" "unprognostic (2.86e-1)" "unprognostic (2.14e-1)" "unprognostic (1.30e-1)" "unprognostic (9.62e-2)" 5.6 4.7 0.0 27.9 0.0 19.9 15.6 0.0 0.4 5.1 0.0 54.1 88.1 4.4 0.5 8.4 4.3 10.7 1.4 0.0 0.5 2.3 3.5 8.3 40.8 0.3 0.0 2.5 1.7 0.1 0.2 0.0 0.2 4.4 23.1 0.0 70.1 0.6 0.1 0.2 23.1 0.9 0.0 107.7 113.1 0.8 0.1 20.0 5.7 0.0 104.2 19.0 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 85.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.2 112.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 122629.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 134.3 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 2.7 3.0 0.6 111.2 0.0 47.3 0.3 0.1 0.0 0.0 0.1 0.0 128.8 0.0 0.0 0.1 133.0 0.0 0.2 0.1 0.0 0.1 0.3 0.1 25.5 0.0 0.0 0.0 0.4 0.0 0.5 0.3 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 109.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.5 0.0 0.4 3.7 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 IGLJ1 ENSG00000211674 "Immunoglobulin lambda joining 1" A0A0A0MT76 22 22893692-22893818 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "intestine: 95.1;lymphoid tissue: 50.0;salivary gland: 32.5;stomach 1: 40.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "memory B-cell: 19.6;naive B-cell: 11.0" "Lineage enriched" "Detected in single" 31 "B-cells: 19.6" "Group enriched" "Detected in some" 6 "Daudi: 274.6;U-266/70: 310.0;U-698: 88.7" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "unprognostic (4.18e-4)" "unprognostic (4.80e-3)" "unprognostic (6.97e-2)" "unprognostic (4.68e-1)" 2.3 0.6 0.1 43.3 0.1 9.8 1.8 0.2 0.6 0.0 0.4 17.1 95.1 0.8 0.0 2.0 0.4 5.1 0.2 0.0 0.1 0.2 0.1 2.7 50.0 0.5 0.1 0.5 0.0 0.0 0.0 0.2 0.3 0.6 13.5 0.0 32.5 0.0 0.0 0.0 43.4 2.6 0.2 31.5 40.8 1.3 0.2 5.2 0.0 0.0 34.5 4.5 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 274.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.3 3.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 310.0 37.0 88.7 0.0 0.9 0.0 0.0 0.1 0.1 0.1 0.0 0.0 19.6 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.1 0.1 0.2 0.6 0.0 0.1 0.5 0.1 0.3 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLJ2 ENSG00000211676 "Immunoglobulin lambda joining 2" 22 22899481-22899655 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 260.8;lymphoid tissue: 189.8;stomach 1: 212.7" "Cell type enriched" "Detected in single" 5 "Plasma cells: 1.7" "Group enriched" "Detected in many" 8 "colorectal cancer: 12.9;endometrial cancer: 21.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 12 "memory B-cell: 876.1;naive B-cell: 864.5" "Lineage enriched" "Detected in many" 12 "B-cells: 876.1" "Cell line enhanced" "Detected in some" "Daudi: 10.8;HMC-1: 34.1;RH-30: 89.7;U-698: 19.8" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (6.99e-3)" "unprognostic (5.36e-2)" "unprognostic (5.54e-2)" "unprognostic (1.13e-2)" "unprognostic (5.94e-7)" "unprognostic (1.51e-2)" "unprognostic (3.63e-2)" "unprognostic (3.66e-2)" "unprognostic (5.17e-2)" "unprognostic (2.92e-1)" 8.4 54.9 0.2 173.0 0.0 25.4 11.2 0.1 0.8 6.1 0.1 134.5 260.8 2.9 4.2 13.5 1.0 12.5 2.9 0.1 0.2 2.1 6.9 21.5 94.5 0.3 0.0 4.7 5.9 0.1 0.0 0.0 0.9 4.0 31.1 0.0 75.6 4.2 0.0 0.2 206.0 1.9 0.1 128.3 212.7 2.3 0.0 15.5 0.3 0.0 189.8 60.8 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.7 89.7 1.3 0.0 0.0 0.8 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 1.0 0.0 0.6 19.8 0.0 0.5 0.0 1.4 1.9 0.6 0.4 0.2 0.7 876.1 0.3 0.3 0.9 864.5 0.2 0.4 9.3 0.7 0.8 71.8 0.5 136.5 0.2 0.0 0.1 0.8 0.1 0.2 0.3 0.0 0.9 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLJ3 ENSG00000211678 "Immunoglobulin lambda joining 3" 22 22904850-22905025 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "intestine: 552.2;lymphoid tissue: 227.6;salivary gland: 149.1;stomach 1: 462.5;urinary bladder: 147.8" "Group enriched" "Detected in some" 44 "B-cells: 4.5;Plasma cells: 4.3" "Group enriched" "Detected in some" 13 "colorectal cancer: 5.1;endometrial cancer: 10.3" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Group enriched" "Detected in many" 24 "memory B-cell: 1223.9;naive B-cell: 1139.6" "Lineage enriched" "Detected in many" 25 "B-cells: 1223.9" "Group enriched" "Detected in some" 7 "Daudi: 53.6;REH: 69.6;U-266/70: 42.8;U-266/84: 22.5" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.19e-1)" "unprognostic (2.06e-3)" "unprognostic (2.05e-1)" "unprognostic (1.37e-1)" "unprognostic (5.00e-1)" 5.7 29.4 0.4 212.4 0.3 37.4 32.5 0.1 1.5 9.7 0.4 130.1 552.2 3.2 0.0 40.0 4.0 32.7 3.1 0.1 0.1 2.9 9.9 41.7 132.1 0.4 0.2 31.1 1.9 0.0 0.0 0.1 0.1 9.6 71.4 0.0 149.1 1.6 0.0 1.5 205.9 6.1 0.0 207.6 462.5 6.1 0.1 23.2 0.8 0.0 227.6 147.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 53.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 69.6 2.5 6.7 0.0 0.0 0.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 1.0 42.8 22.5 4.3 0.0 0.0 0.0 0.8 1.6 0.7 0.9 0.3 4.3 1223.9 0.8 0.5 1.3 1139.6 0.4 0.5 8.5 0.6 1.2 49.2 0.8 193.9 0.4 0.3 0.1 1.5 0.1 0.1 0.4 0.2 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV1-36 ENSG00000211655 "Immunoglobulin lambda variable 1-36" A0A0B4J1U3 22 22431958-22432465 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 268.7;stomach 1: 122.4;urinary bladder: 86.4" "Cell type enriched" "Detected in some" 13 "Plasma cells: 59.2" "Cancer enhanced" "Detected in many" "lung cancer: 33.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 625 "memory B-cell: 60.9;naive B-cell: 85.8" "Lineage enriched" "Detected in single" 731 "B-cells: 85.8" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 980000000 "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.55e-4)" "unprognostic (5.15e-2)" "unprognostic (2.04e-2)" "prognostic favorable (2.60e-4)" "unprognostic (1.11e-3)" "unprognostic (1.15e-2)" "unprognostic (1.50e-1)" "unprognostic (6.51e-2)" "unprognostic (2.12e-1)" "unprognostic (4.53e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.64e-5)" "unprognostic (2.99e-2)" "unprognostic (5.76e-2)" "unprognostic (1.54e-1)" "unprognostic (1.07e-1)" 1.8 0.3 0.0 19.6 0.0 14.4 23.7 0.0 0.1 6.0 0.0 28.2 21.6 0.7 0.6 10.5 9.1 7.3 6.0 0.0 0.0 3.3 3.3 8.7 16.6 0.0 0.0 1.7 1.1 0.0 0.1 0.0 0.0 1.6 44.7 0.0 37.3 3.0 0.0 0.6 12.3 0.8 0.0 108.1 122.4 0.3 0.0 30.5 2.8 0.0 268.7 86.4 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 60.9 0.0 0.0 0.0 85.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGLV1-40 ENSG00000211653 "Immunoglobulin lambda variable 1-40" P01703 22 22409766-22410282 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1291.5;stomach 1: 1287.4" "Cell type enriched" "Detected in some" 358 "Plasma cells: 43406.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 3.0" "Group enriched" "Detected in some" 496 "memory B-cell: 666.4;naive B-cell: 576.7" "Lineage enriched" "Detected in many" 532 "B-cells: 666.4" "Cell line enhanced" "Detected in some" "Daudi: 3.5;RPMI-8226: 2.2;SH-SY5Y: 3.4;TIME: 2.3" "Immunoglobulin genes" NA NA 2300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.64e-3)" "unprognostic (4.68e-3)" "unprognostic (3.88e-2)" "unprognostic (3.37e-3)" "unprognostic (9.60e-3)" "prognostic favorable (5.74e-6)" "unprognostic (2.39e-2)" "unprognostic (1.53e-1)" "unprognostic (8.43e-2)" "unprognostic (5.51e-2)" "unprognostic (1.06e-1)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.44e-6)" "unprognostic (1.51e-1)" "unprognostic (1.57e-1)" "unprognostic (1.34e-1)" "unprognostic (4.57e-2)" 43.4 13.0 0.8 203.5 0.5 114.3 138.5 0.1 3.0 68.1 1.1 553.8 551.6 14.8 0.6 125.4 21.5 236.0 15.2 0.2 0.2 28.8 28.3 115.4 282.5 0.3 0.2 56.6 10.0 1.1 3.4 0.6 0.6 46.1 336.7 4.2 413.8 19.7 1.2 3.1 287.2 14.3 0.2 1029.8 1287.4 7.2 0.3 179.2 61.2 0.0 1291.5 464.8 19.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 1.0 1.1 0.0 0.0 0.2 0.8 2.2 0.0 0.0 1.3 3.4 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.4 0.7 0.7 1.1 1.1 0.8 0.0 0.3 0.0 0.4 0.7 0.2 0.3 0.1 0.6 666.4 0.3 0.3 0.6 576.7 0.1 0.2 1.2 0.3 0.3 0.6 0.4 53.7 0.8 0.5 0.1 3.0 0.2 0.2 0.3 0.2 0.6 0.2 0.3 1.0 0.0 0.0 0.0 0.0 121.0 0.0 0.0 0.0 2.2 0.0 0.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 1.2 8.0 0.0 0.0 0.0 28.6 64.2 0.0 0.0 0.0 1.8 0.9 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 43406.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 7.4 0.0 0.1 0.0 IGLV1-44 ENSG00000211651 "Immunoglobulin lambda variable 1-44" P01699 22 22380766-22381347 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 589.7;lymphoid tissue: 1918.7;stomach 1: 534.3" "Cell type enriched" "Detected in some" 108 "Plasma cells: 12023.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 840 "memory B-cell: 968.8;naive B-cell: 850.4" "Lineage enriched" "Detected in many" 894 "B-cells: 968.8" "Cell line enhanced" "Detected in some" "Daudi: 21.3;RPMI-8226: 5.5;SCLC-21H: 4.1;U-698: 15.2" "Immunoglobulin genes" NA NA 4000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.88e-3)" "unprognostic (1.51e-2)" "unprognostic (2.40e-2)" "unprognostic (7.23e-3)" "unprognostic (4.81e-3)" "prognostic favorable (4.71e-5)" "unprognostic (2.18e-2)" "unprognostic (1.90e-1)" "unprognostic (1.05e-1)" "unprognostic (3.10e-2)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (6.55e-8)" "unprognostic (1.85e-1)" "unprognostic (1.98e-1)" "unprognostic (6.48e-2)" "unprognostic (5.49e-2)" 33.9 2.0 0.1 297.2 0.0 133.4 110.2 0.0 0.8 14.3 0.0 378.7 589.7 11.8 0.0 80.1 19.5 78.7 17.5 0.0 0.0 18.7 17.1 122.2 519.5 1.3 0.2 15.3 3.6 0.0 2.6 0.0 0.4 13.8 263.1 0.0 273.0 9.4 0.7 2.4 236.5 21.4 0.0 608.7 534.3 11.6 0.1 117.8 35.1 0.0 1918.7 240.5 16.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 5.5 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 968.8 0.0 0.0 0.7 850.4 0.0 0.0 0.0 0.0 0.1 1.0 0.1 100.0 0.1 0.0 0.0 0.8 0.0 0.0 1.3 0.2 0.4 0.0 0.1 0.8 0.0 0.0 0.6 0.0 111.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 2.7 0.0 0.0 0.0 3.5 48.4 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12023.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.3 0.0 IGLV1-47 ENSG00000211648 "Immunoglobulin lambda variable 1-47" P01700 22 22357739-22358260 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 706.6;lymphoid tissue: 1804.0;stomach 1: 625.5" "Cell type enriched" "Detected in some" 114 "Plasma cells: 10777.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 638 "memory B-cell: 1518.1;naive B-cell: 819.6" "Lineage enriched" "Detected in many" 828 "B-cells: 1518.1" "Cell line enhanced" "Detected in some" "HL-60: 2.1;RH-30: 2.1;RPMI-8226: 4.2;SCLC-21H: 2.7;SH-SY5Y: 2.4;U-698: 7.1" "Immunoglobulin genes" NA NA 3000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.19e-3)" "unprognostic (2.69e-2)" "unprognostic (1.11e-2)" "unprognostic (1.33e-2)" "unprognostic (1.26e-1)" "prognostic favorable (2.66e-4)" "unprognostic (4.44e-2)" "unprognostic (1.09e-1)" "unprognostic (5.69e-2)" "unprognostic (3.14e-2)" "unprognostic (2.28e-1)" "unprognostic (2.64e-1)" "prognostic unfavorable (5.12e-8)" "unprognostic (5.00e-3)" "unprognostic (1.62e-1)" "unprognostic (7.08e-2)" "unprognostic (1.15e-2)" 36.0 216.0 0.6 323.0 0.4 162.3 200.5 0.4 2.3 82.1 0.7 706.6 704.7 23.8 3.0 163.7 21.3 112.7 27.2 0.2 0.5 23.2 31.8 126.7 689.2 2.6 0.4 43.5 8.9 4.9 2.1 0.5 1.2 22.5 531.5 0.2 526.6 70.2 0.7 4.7 332.8 34.7 0.5 813.7 625.5 9.8 0.4 260.1 34.1 0.0 1804.0 367.0 10.3 2.4 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.7 2.1 4.2 0.0 0.0 2.7 2.4 0.5 0.0 0.0 0.1 0.0 0.3 0.9 0.0 0.0 0.0 0.1 0.6 0.0 7.1 0.0 0.9 0.0 0.7 1.2 0.5 0.7 0.1 0.5 1518.1 0.7 0.6 1.0 819.6 0.3 0.6 0.6 0.5 0.5 1.8 0.6 159.6 0.6 0.4 0.4 2.3 0.2 0.5 2.6 0.4 1.2 0.5 0.4 2.4 0.0 0.0 0.0 0.0 94.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.7 0.0 0.0 0.0 1.7 29.0 0.0 0.0 0.0 0.7 1.7 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10777.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.3 0.0 IGLV1-51 ENSG00000211644 "Immunoglobulin lambda variable 1-51" P01701 22 22322472-22322969 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 1318.8;lymphoid tissue: 3027.3;urinary bladder: 1584.8" "Cell type enriched" "Detected in some" 312 "Plasma cells: 34336.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "memory B-cell: 275.9;naive B-cell: 178.3" "Lineage enriched" "Detected in many" 10 "B-cells: 275.9" "Cell line enhanced" "Detected in many" "HEK 293: 17.9" "Immunoglobulin genes" NA NA 1700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.85e-4)" "unprognostic (1.71e-2)" "unprognostic (3.12e-3)" "unprognostic (1.76e-3)" "unprognostic (1.61e-1)" "prognostic favorable (1.95e-5)" "unprognostic (3.55e-3)" "unprognostic (3.78e-2)" "unprognostic (1.84e-1)" "unprognostic (1.61e-2)" "unprognostic (1.41e-1)" "unprognostic (4.86e-1)" "prognostic unfavorable (1.40e-5)" "unprognostic (1.21e-1)" "unprognostic (5.70e-2)" "unprognostic (1.89e-1)" "unprognostic (1.07e-1)" 43.5 318.8 1.1 484.8 1.9 274.1 627.0 4.6 7.1 73.2 2.0 1318.8 1139.1 38.0 16.9 287.4 52.8 238.0 70.2 1.4 1.6 32.7 53.3 179.1 343.1 4.0 1.4 185.0 39.0 5.8 4.1 1.5 4.2 34.4 930.0 3.1 695.2 49.5 1.9 13.1 702.1 49.8 1.9 934.5 956.7 11.7 1.5 274.0 63.0 1.7 3027.3 1584.8 17.7 2.7 1.3 0.6 1.6 3.8 3.5 1.7 5.9 1.4 3.2 3.1 2.0 2.3 1.0 8.8 1.6 0.8 1.1 3.1 1.9 3.8 2.2 1.4 17.9 3.9 4.5 2.4 0.7 3.4 1.7 5.2 1.0 2.7 0.3 0.4 3.1 0.9 3.9 0.9 3.0 1.6 2.6 3.8 3.0 2.8 4.1 2.3 2.7 8.8 3.6 1.4 8.3 4.9 2.0 1.4 1.8 0.9 2.7 0.3 4.3 4.4 9.2 1.0 1.2 2.0 2.0 2.0 0.4 2.8 0.8 0.1 0.5 0.0 0.2 0.2 26.3 275.9 0.2 0.3 0.1 178.3 0.7 0.5 0.4 0.1 0.3 0.2 0.2 26.4 1.1 1.9 4.6 7.1 1.4 1.6 4.0 1.4 4.2 1.9 1.5 2.7 0.0 0.0 0.5 0.0 109.8 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 4.8 35.7 0.1 0.0 0.0 0.7 1.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 34336.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.1 19.3 0.0 0.0 9.4 0.0 0.0 0.0 IGLV2-11 ENSG00000211668 "Immunoglobulin lambda variable 2-11" P01706 22 22792491-22793007 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1542.6;lymphoid tissue: 2926.9" "Cell type enriched" "Detected in some" 85 "Plasma cells: 7693.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 37 "memory B-cell: 1402.5;naive B-cell: 850.1" "Lineage enriched" "Detected in many" 46 "B-cells: 1402.5" "Cell line enhanced" "Detected in some" "Karpas-707: 75.0;U-266/70: 20.9;U-266/84: 15.3" "Immunoglobulin genes" NA NA 980000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (9.76e-3)" "unprognostic (6.86e-2)" "unprognostic (3.46e-3)" "unprognostic (7.67e-3)" "unprognostic (2.82e-3)" "prognostic favorable (4.74e-5)" "unprognostic (1.18e-2)" "unprognostic (1.12e-1)" "unprognostic (9.19e-2)" "unprognostic (1.77e-2)" "unprognostic (2.27e-1)" "unprognostic (2.72e-1)" "prognostic unfavorable (1.38e-7)" "unprognostic (3.93e-2)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (2.27e-1)" 33.6 7.3 0.6 344.7 0.3 157.3 447.8 0.1 2.7 27.7 0.8 1455.8 1542.6 18.4 0.5 212.0 30.0 191.3 44.6 0.2 0.7 22.4 41.1 179.8 680.1 1.5 0.2 30.5 22.4 0.6 2.1 0.5 1.1 17.0 868.3 0.0 425.0 36.0 1.7 2.9 713.8 21.3 0.6 637.7 876.1 75.4 0.5 286.4 62.2 0.0 2926.9 661.1 14.8 2.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 3.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 75.0 0.0 0.0 0.9 4.6 1.1 0.0 0.0 0.8 2.8 8.3 0.0 0.0 2.9 4.8 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 1.1 0.3 1.6 20.9 15.3 0.0 0.3 1.1 0.0 1.2 1.0 0.7 11.5 0.2 1.4 1402.5 1.5 5.9 0.9 850.1 1.0 4.6 30.2 11.1 0.8 0.9 0.8 149.8 0.6 0.3 0.1 2.7 0.2 0.7 1.5 0.2 1.1 0.6 0.5 2.2 0.0 0.0 0.0 0.0 89.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 15.8 0.0 0.0 0.0 1.4 11.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7693.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGLV2-14 ENSG00000211666 "Immunoglobulin lambda variable 2-14" P01704 22 22758700-22759218 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2622.2;lymphoid tissue: 5374.9;stomach 1: 2530.1" "Cell type enriched" "Detected in some" 179 "Plasma cells: 58316.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 50 "memory B-cell: 3655.3;naive B-cell: 2657.4" "Lineage enriched" "Detected in all" 58 "B-cells: 3655.3" "Cell line enriched" "Detected in many" 5 "RPMI-8226: 22672.4" "Immunoglobulin genes" NA NA 2200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.23e-4)" "unprognostic (9.05e-3)" "unprognostic (1.18e-2)" "unprognostic (7.20e-3)" "unprognostic (2.00e-2)" "prognostic favorable (2.21e-4)" "unprognostic (3.69e-1)" "unprognostic (1.97e-1)" "unprognostic (7.99e-2)" "unprognostic (1.83e-2)" "unprognostic (9.11e-2)" "unprognostic (4.97e-1)" "prognostic unfavorable (5.74e-7)" "unprognostic (1.15e-1)" "unprognostic (1.33e-1)" "unprognostic (1.42e-1)" "unprognostic (2.87e-2)" 83.9 192.1 0.8 754.9 1.7 357.8 749.8 0.5 6.4 119.7 3.8 2622.2 2470.7 47.8 20.7 245.2 49.0 442.1 45.2 0.6 1.0 54.3 102.1 399.3 3320.0 1.6 0.6 75.3 52.1 4.5 5.6 1.2 1.0 71.0 1074.1 0.1 797.3 119.4 2.7 21.3 1262.7 62.0 1.4 1580.6 2530.1 13.9 1.3 586.1 116.5 0.5 5374.9 1165.2 35.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.4 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 5.8 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4453.2 0.0 0.0 8.7 8.0 1.7 0.0 0.0 4.9 3.7 22672.4 0.0 0.0 11.8 11.1 0.4 17.3 0.0 0.0 7.1 0.0 5.1 0.0 4.1 5.7 1.1 20.4 37.7 1.4 12.1 1.7 5.0 3.9 5.3 1.7 47.1 1.0 28.8 3655.3 9.6 53.9 3.3 2657.4 1.4 12.7 11.6 62.5 2.4 2.2 2.1 451.3 0.8 1.7 0.5 6.4 0.6 1.0 1.6 0.6 1.0 1.4 1.3 2.1 0.0 0.0 0.0 0.0 324.1 0.0 0.0 0.0 1.2 0.0 0.3 0.3 0.0 2.8 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 14.7 0.0 0.0 0.0 9.9 121.8 0.0 0.0 0.0 1.4 1.7 0.0 0.0 0.0 0.3 0.0 3.5 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 58316.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 36.6 0.0 0.8 0.0 IGLV2-18 ENSG00000211664 "Immunoglobulin lambda variable 2-18" A0A075B6J9 22 22734607-22735089 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 271.5;lymphoid tissue: 224.4" "Cell type enriched" "Detected in some" 210 "Plasma cells: 2488.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 44 "memory B-cell: 321.2;naive B-cell: 126.9" "Lineage enriched" "Detected in many" 64 "B-cells: 321.2" "Group enriched" "Detected in some" 7 "RPMI-8226: 13.4;U-266/70: 22.3;U-266/84: 7.2" "Immunoglobulin genes" NA NA 570000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.06e-5)" "unprognostic (2.81e-2)" "unprognostic (7.47e-3)" "unprognostic (1.13e-2)" "prognostic favorable (7.75e-4)" "unprognostic (1.44e-2)" "unprognostic (1.60e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (7.58e-2)" "unprognostic (2.41e-2)" "prognostic unfavorable (1.86e-7)" "unprognostic (1.95e-1)" "unprognostic (9.70e-2)" "unprognostic (1.66e-1)" "unprognostic (1.27e-2)" 3.4 0.3 0.0 73.0 0.0 23.7 67.1 0.0 0.3 6.7 0.1 271.5 262.0 4.2 0.0 39.6 10.8 36.3 12.5 0.0 0.0 2.0 2.8 12.6 37.6 0.1 0.0 4.1 1.1 2.1 0.2 0.1 0.4 1.7 138.6 0.0 64.3 4.9 0.1 0.3 150.2 6.5 0.0 95.8 72.5 0.5 0.0 22.1 2.8 0.0 224.4 18.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 13.4 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 22.3 7.2 0.1 0.1 0.1 0.0 0.2 1.8 0.0 1.6 0.0 0.8 321.2 0.3 1.3 0.1 126.9 0.7 0.6 0.5 5.0 0.1 0.2 0.1 69.7 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 7.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2488.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGLV2-23 ENSG00000211660 "Immunoglobulin lambda variable 2-23" P01705 22 22697789-22698407 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 691.1;lymphoid tissue: 1598.0;stomach 1: 672.8" "Cell type enriched" "Detected in some" 132 "Plasma cells: 12487.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 369 "memory B-cell: 2072.7;naive B-cell: 2596.0" "Lineage enriched" "Detected in all" 410 "B-cells: 2596.0" "Cell line enriched" "Detected in some" 10 "Karpas-707: 85411.7" "Immunoglobulin genes" NA NA 540000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.43e-5)" "unprognostic (7.99e-2)" "unprognostic (3.89e-2)" "unprognostic (2.35e-3)" "unprognostic (2.73e-2)" "unprognostic (1.30e-2)" "unprognostic (9.33e-2)" "unprognostic (2.13e-1)" "unprognostic (1.19e-1)" "unprognostic (5.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.50e-7)" "unprognostic (8.20e-2)" "unprognostic (7.79e-2)" "unprognostic (1.20e-1)" "unprognostic (7.42e-2)" 16.0 38.9 0.7 306.7 0.3 103.6 184.7 0.1 1.5 45.2 0.6 634.1 691.1 16.2 1.3 78.7 25.5 66.8 19.9 0.2 0.1 18.6 26.2 160.8 623.2 1.0 0.1 16.3 8.2 0.6 1.7 0.6 0.4 10.8 457.1 0.0 356.7 38.1 0.5 2.1 517.3 16.1 0.3 530.5 672.8 5.9 0.2 277.6 39.1 0.4 1598.0 274.5 11.9 0.3 0.8 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.0 0.0 65.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 82.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 85411.7 0.0 0.0 2.2 4.2 0.5 0.0 0.0 0.7 1.9 8843.9 0.0 0.0 2.1 4.5 0.0 4.7 0.0 0.0 1.9 0.0 1.0 0.0 1.1 3.4 0.7 213.9 81.1 0.5 92.6 0.2 35.5 1.8 3.1 1.0 1.6 0.9 1.3 2072.7 1.6 0.8 2.6 2596.0 0.6 0.9 6.3 1.6 1.7 0.9 1.3 231.7 0.7 0.3 0.1 1.5 0.2 0.1 1.0 0.1 0.4 0.3 0.2 0.3 0.0 0.0 0.0 0.0 94.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 13.7 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12487.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 39.5 0.0 0.2 0.0 IGLV2-8 ENSG00000278196 "Immunoglobulin lambda variable 2-8" P01709 22 22822658-22823289 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1141.8;lymphoid tissue: 1012.4" "Cell type enriched" "Detected in some" 80 "Plasma cells: 5288.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 125 "memory B-cell: 1439.0;naive B-cell: 2097.3" "Lineage enriched" "Detected in all" 149 "B-cells: 2097.3" "Group enriched" "Detected in many" 617 "U-266/70: 64161.5;U-266/84: 56786.5" "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.92e-4)" "unprognostic (1.29e-1)" "unprognostic (7.17e-3)" "unprognostic (1.05e-2)" "unprognostic (1.65e-1)" "prognostic favorable (5.07e-5)" "unprognostic (2.74e-2)" "unprognostic (1.51e-1)" "unprognostic (1.34e-1)" "unprognostic (5.05e-2)" "unprognostic (1.61e-1)" "unprognostic (6.55e-2)" "prognostic unfavorable (3.00e-5)" "unprognostic (2.04e-2)" "unprognostic (2.67e-1)" "unprognostic (9.90e-2)" "unprognostic (1.62e-1)" 18.7 7.0 1.1 325.0 0.6 96.0 155.2 0.3 2.4 26.0 1.7 1141.8 977.0 9.4 3.5 91.4 7.9 132.4 30.5 0.3 0.3 15.4 24.3 59.2 228.2 0.8 0.3 57.2 30.3 1.4 1.4 0.2 0.7 9.0 250.6 0.0 255.5 60.3 0.6 1.9 451.5 20.1 0.8 437.7 433.9 3.4 0.3 90.6 23.7 0.0 1012.4 259.0 10.3 1.0 62.7 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 7.6 0.0 0.0 23.1 0.0 0.0 0.0 22.3 0.0 0.5 0.0 0.0 0.0 0.7 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.3 0.0 0.0 11.3 1.9 14.8 0.0 0.0 97.9 0.9 10.1 0.0 0.0 1.4 2.8 0.2 0.0 9.3 0.0 0.0 29.5 0.9 0.0 9.8 0.6 38.9 64161.5 56786.5 20.4 0.0 10.1 0.0 1.2 2.4 0.6 2.1 0.7 0.9 1439.0 1.3 1.5 1.9 2097.3 0.4 1.0 14.1 1.3 1.4 0.6 0.7 174.0 1.1 0.6 0.3 2.4 0.3 0.3 0.8 0.3 0.7 0.8 0.3 1.0 0.0 3.2 0.0 0.0 65.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 2.5 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5288.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.2 0.0 IGLV3-1 ENSG00000211673 "Immunoglobulin lambda variable 3-1" P01715 22 22880706-22881396 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1234.9;lymphoid tissue: 3325.7;stomach 1: 1460.4" "Cell type enriched" "Detected in some" 321 "Plasma cells: 56277.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 725 "memory B-cell: 779.5;naive B-cell: 1038.5" "Lineage enriched" "Detected in many" 828 "B-cells: 1038.5" "Cell line enhanced" "Detected in some" "Daudi: 14.4;RPMI-8226: 4.5;SCLC-21H: 9.1;SH-SY5Y: 9.9" HPA003285 Approved "Immunoglobulin genes" NA NA 4300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (9.70e-5)" "unprognostic (9.06e-2)" "unprognostic (5.39e-3)" "unprognostic (2.37e-2)" "unprognostic (8.13e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.30e-2)" "unprognostic (1.21e-1)" "unprognostic (1.92e-2)" "unprognostic (1.63e-2)" "unprognostic (2.86e-1)" "unprognostic (2.82e-1)" "prognostic unfavorable (9.06e-9)" "unprognostic (2.70e-2)" "unprognostic (4.35e-1)" "unprognostic (1.30e-1)" "unprognostic (2.69e-1)" 44.5 70.9 0.3 485.2 0.2 332.4 317.1 0.2 2.0 192.0 0.9 1234.9 643.4 39.2 0.0 217.7 19.2 310.4 28.1 0.1 0.4 26.3 70.1 176.2 1117.0 1.0 0.3 34.1 7.6 2.7 2.0 0.7 1.5 21.9 684.4 0.2 627.3 19.6 1.2 4.1 481.7 37.2 0.4 654.2 1460.4 56.0 0.3 335.5 35.9 0.0 3325.7 679.7 30.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.1 0.0 0.0 1.1 0.0 0.0 0.0 1.9 0.0 0.6 0.0 0.0 0.0 2.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.2 2.4 0.8 0.0 0.0 0.5 3.0 4.5 0.0 0.0 9.1 9.9 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.6 0.6 1.7 1.8 1.2 2.8 0.0 0.3 0.0 0.7 1.1 0.5 0.3 0.4 0.4 779.5 0.6 0.2 1.2 1038.5 0.2 0.3 0.6 0.4 0.8 0.5 0.5 52.3 0.3 0.2 0.2 2.0 0.1 0.4 1.0 0.3 1.5 0.4 0.3 0.9 0.0 3.2 0.0 0.0 111.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 122.5 0.0 0.0 0.0 0.0 0.0 10.7 174.8 0.0 0.0 0.0 1.1 1.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 56277.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 11.7 0.0 0.2 0.0 IGLV3-10 ENSG00000211669 "Immunoglobulin lambda variable 3-10" A0A075B6K4 22 22811747-22812281 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 317.0;lymphoid tissue: 707.7;stomach 1: 288.7" "Cell type enriched" "Detected in some" 52 "Plasma cells: 1090.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebral cortex: 3.3;medulla oblongata: 1.8" "Group enriched" "Detected in some" 786 "memory B-cell: 548.7;naive B-cell: 315.0" "Lineage enriched" "Detected in single" 998 "B-cells: 548.7" "Cell line enhanced" "Detected in some" "Daudi: 4.9;HL-60: 1.0;RH-30: 1.6" HPA003285 Approved "Immunoglobulin genes" NA NA 2000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "unprognostic (6.00e-2)" "unprognostic (2.28e-2)" "unprognostic (1.65e-2)" "unprognostic (1.73e-2)" "unprognostic (6.99e-2)" "prognostic favorable (1.27e-4)" "unprognostic (7.40e-3)" "unprognostic (2.44e-2)" "unprognostic (9.91e-2)" "unprognostic (9.55e-2)" "unprognostic (2.79e-1)" "unprognostic (3.55e-1)" "prognostic unfavorable (6.95e-8)" "unprognostic (9.23e-2)" "unprognostic (1.48e-1)" "unprognostic (1.77e-1)" "unprognostic (6.04e-2)" 33.3 112.9 0.5 144.0 0.4 65.5 111.1 0.1 3.3 41.3 0.6 308.0 176.3 7.6 4.5 56.3 7.9 43.5 20.5 0.1 0.2 12.2 20.8 48.0 230.5 1.8 0.2 14.6 10.8 0.9 0.8 0.4 0.6 11.0 317.0 0.0 139.7 10.8 0.2 8.1 94.9 5.8 0.1 217.1 288.7 97.4 0.2 25.9 8.6 0.0 707.7 140.2 7.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 1.6 0.4 0.0 0.0 0.2 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.5 0.3 0.3 0.2 0.0 0.2 548.7 0.1 0.2 0.2 315.0 0.0 0.2 0.3 0.1 0.1 0.3 0.1 43.2 0.5 0.4 0.1 3.3 0.1 0.2 1.8 0.2 0.6 0.1 0.2 0.2 0.0 0.0 0.6 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 7.1 0.0 1.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1090.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.2 0.0 IGLV3-12 ENSG00000211667 "Immunoglobulin lambda variable 3-12" A0A075B6K2 22 22771824-22772582 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 4.2;memory B-cell: 9.2;memory CD8 T-cell: 4.0;naive B-cell: 6.7;NK-cell: 5.6" "Group enriched" "Detected in many" 64 "B-cells: 9.2;NK-cells: 5.6;T-cells: 4.2" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 850000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.92e-3)" "unprognostic (4.30e-2)" "unprognostic (1.68e-3)" "unprognostic (2.03e-2)" "prognostic favorable (8.39e-6)" "unprognostic (8.44e-2)" "unprognostic (4.62e-2)" "unprognostic (5.01e-2)" "unprognostic (2.88e-2)" "unprognostic (3.15e-4)" "unprognostic (3.62e-2)" "unprognostic (4.71e-1)" "unprognostic (3.14e-1)" "unprognostic (1.52e-1)" 0.8 1.2 0.0 3.9 0.0 2.7 1.9 0.0 0.3 0.3 0.1 7.3 5.5 0.5 0.0 1.0 0.6 3.3 0.0 0.0 0.0 0.1 0.5 2.7 15.3 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.5 3.8 0.0 5.1 1.7 0.0 0.2 2.7 0.1 0.0 4.6 8.2 0.9 0.0 3.9 0.2 0.0 30.1 1.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 1.1 9.2 1.0 4.0 0.0 6.7 0.0 0.2 0.0 5.6 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV3-19 ENSG00000211663 "Immunoglobulin lambda variable 3-19" P01714 22 22720623-22721145 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1026.7;lymphoid tissue: 1979.7;stomach 1: 1240.2" "Cell type enriched" "Detected in some" 61 "Plasma cells: 3121.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 355 "memory B-cell: 618.3;naive B-cell: 503.7" "Lineage enriched" "Detected in many" 391 "B-cells: 618.3" "Cell line enhanced" "Detected in some" "RPMI-8226: 6.2;SCLC-21H: 9.4;SH-SY5Y: 10.7;U-251 MG: 4.2" "Immunoglobulin genes" NA NA 1200000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.92e-5)" "unprognostic (1.52e-2)" "unprognostic (1.60e-3)" "prognostic favorable (6.11e-5)" "unprognostic (1.14e-1)" "unprognostic (1.24e-3)" "unprognostic (9.58e-3)" "unprognostic (3.57e-1)" "unprognostic (1.55e-1)" "unprognostic (1.00e-1)" "unprognostic (3.13e-1)" "unprognostic (3.03e-1)" "prognostic unfavorable (9.37e-10)" "unprognostic (2.10e-1)" "unprognostic (2.31e-1)" "unprognostic (2.44e-1)" "unprognostic (8.52e-2)" 49.1 20.1 0.1 402.2 0.3 185.1 313.5 0.1 2.4 69.2 0.3 1026.7 713.6 19.0 263.4 154.0 65.8 182.4 36.9 0.1 0.3 26.0 57.5 192.2 464.9 1.5 0.4 44.9 11.5 1.3 2.7 0.4 0.4 17.2 912.2 0.0 304.9 62.4 0.9 4.8 385.2 34.9 0.6 714.2 1240.2 6.0 0.4 435.0 55.4 0.0 1979.7 642.5 13.6 1.1 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 2.7 0.3 0.0 0.0 0.1 0.9 6.2 0.0 0.0 9.4 10.7 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.4 0.0 4.2 0.8 0.5 0.7 0.0 0.5 0.0 0.4 0.4 1.0 0.5 0.3 0.7 618.3 0.2 0.3 0.5 503.7 0.4 0.3 1.5 0.3 0.4 0.6 0.4 36.2 0.1 0.3 0.1 2.4 0.1 0.3 1.5 0.4 0.4 0.6 0.4 1.1 0.0 0.0 0.0 0.0 51.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.4 15.8 0.0 1.3 0.0 2.2 1.8 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3121.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 IGLV3-21 ENSG00000211662 "Immunoglobulin lambda variable 3-21" P80748 22 22711689-22713203 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1812.1;urinary bladder: 773.9" "Cell type enriched" "Detected in some" 59 "Plasma cells: 5013.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 339 "memory B-cell: 432.0;naive B-cell: 224.7" "Lineage enriched" "Detected in single" 445 "B-cells: 432.0" "Cell line enriched" "Detected in some" 103 "REH: 282.7" "Immunoglobulin genes" NA NA 4700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 14: REH - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.75e-3)" "unprognostic (6.04e-3)" "unprognostic (4.21e-2)" "unprognostic (2.59e-3)" "unprognostic (4.06e-3)" "prognostic favorable (3.26e-7)" "unprognostic (1.63e-1)" "unprognostic (1.78e-1)" "unprognostic (1.53e-1)" "unprognostic (5.30e-2)" "unprognostic (3.86e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (9.54e-8)" "unprognostic (7.83e-2)" "unprognostic (1.88e-1)" "unprognostic (2.67e-1)" "unprognostic (7.52e-2)" 17.6 63.4 0.3 321.9 0.2 248.2 120.7 0.1 1.6 110.0 1.6 357.4 350.4 12.9 0.5 63.1 10.2 120.4 10.8 0.1 0.2 21.5 36.4 108.6 272.7 1.0 0.1 35.6 5.7 0.7 1.4 0.4 0.4 16.8 230.8 0.0 260.8 20.2 0.5 2.3 150.7 9.0 0.3 421.0 504.5 14.4 0.3 171.6 19.9 0.0 1812.1 773.9 17.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 2.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.4 0.5 0.2 0.0 0.0 282.7 1.8 2.0 0.0 0.0 1.6 1.8 0.1 0.3 0.0 0.0 0.0 0.0 2.2 0.0 0.3 0.5 0.5 0.5 0.1 0.2 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.1 432.0 0.1 0.1 0.3 224.7 0.1 0.1 0.9 0.1 0.1 0.2 0.1 36.6 0.3 0.2 0.1 1.6 0.1 0.2 1.0 0.1 0.4 0.3 0.3 1.3 0.0 0.0 0.0 0.0 84.4 0.0 0.0 0.0 4.6 0.0 0.1 0.0 0.1 2.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 4.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 20.4 0.0 0.0 0.0 3.3 2.5 0.1 0.0 0.0 0.0 0.0 1.3 0.0 4.7 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5013.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.2 0.0 0.0 1.8 0.0 0.2 0.0 IGLV3-25 ENSG00000211659 "Immunoglobulin lambda variable 3-25" P01717 22 22686726-22687271 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2440.7;stomach 1: 1015.7" "Cell type enriched" "Detected in some" 41 "Plasma cells: 17441.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 45 "memory B-cell: 545.0;naive B-cell: 794.2" "Lineage enriched" "Detected in many" 53 "B-cells: 794.2" "Cell line enhanced" "Detected in some" "HL-60: 2.6;RPMI-8226: 2.7;SCLC-21H: 4.6;SH-SY5Y: 5.1" HPA003285 Approved "Immunoglobulin genes" NA NA 3200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (5.55e-4)" "unprognostic (8.28e-2)" "unprognostic (4.28e-3)" "unprognostic (2.89e-2)" "unprognostic (2.88e-2)" "prognostic favorable (1.43e-4)" "unprognostic (1.92e-2)" "unprognostic (1.05e-1)" "unprognostic (1.87e-1)" "unprognostic (1.98e-2)" "unprognostic (4.86e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (3.78e-7)" "unprognostic (1.25e-1)" "unprognostic (4.78e-1)" "unprognostic (2.16e-1)" "unprognostic (1.72e-1)" 56.8 163.2 0.2 293.2 0.2 243.2 430.9 0.1 1.7 151.9 1.3 847.4 338.9 20.8 2.1 161.5 49.8 177.1 29.8 0.2 0.3 17.1 45.7 870.5 1024.7 1.8 0.2 21.8 14.5 1.7 1.7 0.5 0.6 18.9 467.5 0.0 532.3 116.5 0.7 2.4 228.9 34.1 0.4 543.5 1015.7 59.8 0.5 155.9 23.1 0.0 2440.7 779.6 20.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.6 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 1.7 0.4 1.7 0.0 0.0 1.6 1.5 2.7 0.0 0.0 4.6 5.1 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.0 0.1 0.8 1.8 0.2 0.7 0.0 1.3 0.0 0.8 0.4 0.3 0.7 0.1 0.2 545.0 0.4 0.1 0.5 794.2 0.2 0.1 14.9 0.3 0.6 0.3 0.3 76.5 0.2 0.2 0.1 1.7 0.2 0.3 1.8 0.2 0.6 0.4 0.5 0.6 0.0 0.0 0.0 0.0 84.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.0 1.9 40.8 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17441.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 417.4 0.0 0.0 0.1 0.0 0.0 3.5 0.0 0.0 0.0 IGLV3-9 ENSG00000211670 "Immunoglobulin lambda variable 3-9" A0A075B6K5 22 22819010-22819756 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 313.9;stomach 1: 117.3" "Cell type enriched" "Detected in some" 9 "Plasma cells: 13.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 51 "memory B-cell: 64.7;naive B-cell: 168.7" "Lineage enriched" "Detected in many" 74 "B-cells: 168.7" "Cell line enriched" "Detected in some" 5 "U-266/70: 41.3" HPA003285 Approved "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (2.59e-4)" "unprognostic (6.52e-3)" "unprognostic (1.95e-1)" "unprognostic (5.40e-2)" "prognostic favorable (9.80e-5)" "unprognostic (1.36e-2)" "unprognostic (1.09e-1)" "unprognostic (1.68e-1)" "unprognostic (1.50e-1)" "unprognostic (2.52e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (6.00e-7)" "unprognostic (3.47e-2)" "unprognostic (4.58e-2)" "unprognostic (4.55e-2)" "unprognostic (3.22e-1)" 1.8 23.5 0.1 84.6 0.0 27.8 14.9 0.0 0.1 7.3 0.1 87.1 58.7 2.0 0.0 20.8 1.8 18.6 7.6 0.0 0.0 3.2 6.2 17.1 139.8 0.7 0.0 3.9 2.4 0.2 0.1 0.0 0.1 1.4 64.0 0.0 46.2 3.1 0.1 1.5 60.3 5.2 0.0 64.6 117.3 1.6 0.1 35.0 3.8 0.0 313.9 72.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 2.1 0.1 0.3 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.9 0.3 0.0 41.3 5.8 0.7 0.0 3.9 0.0 0.0 0.1 0.0 1.2 0.0 2.2 64.7 1.3 1.4 0.0 168.7 0.4 1.8 0.1 0.5 0.1 0.0 0.1 6.5 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 IGLV4-69 ENSG00000211637 "Immunoglobulin lambda variable 4-69" A0A075B6H9 22 22030934-22031472 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 430.3;lymphoid tissue: 461.2;salivary gland: 116.6;stomach 1: 285.6;urinary bladder: 204.0" "Cell type enriched" "Detected in some" 140 "Plasma cells: 4593.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 4 "medulla oblongata: 1.1" "Group enriched" "Detected in some" 302 "memory B-cell: 331.7;naive B-cell: 224.0" "Lineage enriched" "Detected in single" 361 "B-cells: 331.7" "Cell line enhanced" "Detected in some" "Daudi: 1.0;NB-4: 1.0;REH: 1.3;RPMI-8226: 5.4;SH-SY5Y: 1.3" "Immunoglobulin genes" NA NA 320000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.02e-4)" "unprognostic (1.32e-2)" "unprognostic (2.19e-3)" "unprognostic (1.34e-3)" "unprognostic (2.67e-2)" "prognostic favorable (4.04e-5)" "unprognostic (2.59e-3)" "unprognostic (2.50e-1)" "unprognostic (1.67e-1)" "unprognostic (5.57e-2)" "unprognostic (1.85e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (1.89e-5)" "unprognostic (9.74e-2)" "unprognostic (2.27e-1)" "unprognostic (1.23e-1)" "unprognostic (6.08e-2)" 15.6 9.7 0.0 172.4 0.1 43.2 64.1 0.1 0.2 27.9 0.1 325.8 430.3 5.7 0.2 52.2 5.5 44.1 15.1 0.0 0.0 6.2 14.5 72.1 450.4 1.1 0.0 10.6 8.5 0.3 1.1 0.1 0.2 6.3 209.5 0.0 116.6 6.3 0.2 0.7 219.6 3.4 0.0 305.9 285.6 1.4 0.2 82.1 9.8 0.1 461.2 204.0 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 1.3 0.0 5.4 0.0 0.0 0.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.6 0.0 0.6 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.1 331.7 0.2 0.1 0.2 224.0 0.0 0.1 0.9 0.1 0.1 0.1 0.2 32.3 0.0 0.1 0.1 0.2 0.0 0.0 1.1 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 32.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.5 11.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4593.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 IGLV5-45 ENSG00000211650 "Immunoglobulin lambda variable 5-45" A0A087WSX0 22 22375986-22376505 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 40.5;intestine: 43.5;lymphoid tissue: 97.5;salivary gland: 49.0" "Cell type enriched" "Detected in some" 116 "Plasma cells: 6697.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "memory B-cell: 1.2;naive B-cell: 1.1" "Lineage enriched" "Detected in single" 11 "B-cells: 1.2" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 160000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (4.62e-4)" "unprognostic (6.18e-2)" "unprognostic (2.26e-2)" "unprognostic (1.48e-2)" "unprognostic (2.29e-1)" "prognostic favorable (2.70e-5)" "unprognostic (1.58e-3)" "unprognostic (2.77e-1)" "unprognostic (8.89e-2)" "unprognostic (1.06e-1)" "unprognostic (5.16e-2)" "unprognostic (3.08e-1)" "prognostic unfavorable (5.95e-6)" "unprognostic (6.14e-2)" "unprognostic (2.28e-1)" "unprognostic (1.20e-1)" "unprognostic (8.36e-2)" 2.2 0.3 0.0 0.0 0.0 0.4 5.5 0.0 0.4 3.3 0.0 43.5 0.0 0.7 0.0 40.5 2.0 0.0 0.2 0.0 0.0 2.5 3.1 9.6 0.0 0.1 0.0 0.6 0.6 0.0 0.2 0.0 0.1 1.1 0.2 0.0 49.0 0.0 0.1 0.7 42.1 0.0 0.0 97.5 14.1 0.4 0.0 0.0 4.0 0.0 1.4 14.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.8 57.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6697.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.0 IGLV6-57 ENSG00000211640 "Immunoglobulin lambda variable 6-57" P01721 22 22195799-22196276 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1814.6;urinary bladder: 675.2" "Cell type enriched" "Detected in some" 72 "Plasma cells: 10791.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "memory B-cell: 353.9;naive B-cell: 292.4" "Lineage enriched" "Detected in many" 13 "B-cells: 353.9" "Cell line enhanced" "Detected in some" "Daudi: 148.0;RPMI-8226: 40.6;U-266/70: 21.6;U-698: 47.3" "Immunoglobulin genes" NA NA 1900000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.92e-6)" "unprognostic (5.73e-2)" "unprognostic (2.59e-2)" "unprognostic (2.11e-2)" "unprognostic (1.14e-2)" "prognostic favorable (1.36e-5)" "unprognostic (1.87e-2)" "unprognostic (2.56e-1)" "unprognostic (6.55e-2)" "unprognostic (3.87e-2)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.30e-6)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.52e-1)" "unprognostic (1.11e-1)" 15.6 9.1 0.0 220.8 0.1 191.7 215.5 0.0 0.6 82.3 0.4 485.0 351.3 19.1 4.4 171.4 38.2 75.8 39.2 0.1 0.0 10.7 26.8 97.0 237.6 0.6 0.1 20.3 7.7 17.8 1.1 0.4 0.5 17.2 318.8 0.0 249.6 12.7 0.3 3.2 174.3 11.5 0.1 276.6 437.6 15.9 0.1 139.7 15.3 0.0 1814.6 675.2 8.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 148.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.9 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.2 1.0 40.6 0.0 0.0 2.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.2 0.4 21.6 15.2 47.3 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.0 2.3 353.9 0.1 0.1 0.2 292.4 0.1 0.1 27.9 0.1 0.1 1.2 0.2 27.6 0.0 0.1 0.0 0.6 0.1 0.0 0.6 0.1 0.5 0.1 0.1 0.3 0.0 0.0 0.6 0.0 148.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 1.8 26.7 0.0 0.0 0.0 4.4 67.8 0.0 0.0 0.0 3.6 2.8 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.2 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10791.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.0 0.0 6.2 0.0 0.5 0.0 IGLV7-43 ENSG00000211652 "Immunoglobulin lambda variable 7-43" P04211 22 22395018-22395489 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 161.9;lymphoid tissue: 238.7;stomach 1: 115.9" "Cell type enriched" "Detected in some" 57 "Plasma cells: 1304.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 325 "memory B-cell: 132.0;naive B-cell: 54.2" "Lineage enriched" "Detected in single" 461 "B-cells: 132.0" "Cell line enhanced" "Detected in some" "Daudi: 1.9;RPMI-8226: 1.4;U-698: 1.5" HPA003182 Approved "Immunoglobulin genes" NA NA 130000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003182: " "prognostic favorable (6.49e-6)" "unprognostic (7.85e-3)" "prognostic favorable (7.00e-4)" "unprognostic (5.57e-2)" "unprognostic (3.62e-2)" "prognostic favorable (3.08e-5)" "unprognostic (7.63e-3)" "unprognostic (8.20e-2)" "unprognostic (2.42e-1)" "unprognostic (2.54e-1)" "unprognostic (2.55e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (6.29e-2)" "unprognostic (8.34e-2)" "unprognostic (1.68e-1)" "unprognostic (2.29e-1)" 8.0 0.8 0.0 31.2 0.1 15.8 45.7 0.0 0.5 4.9 0.0 161.9 132.8 3.6 0.5 7.9 3.3 22.1 3.5 0.0 0.1 3.1 4.2 13.0 59.0 0.0 0.0 4.1 2.2 0.0 1.0 0.2 0.1 2.3 129.3 0.0 72.5 4.7 0.1 0.5 57.1 17.7 0.0 168.6 115.9 0.5 0.0 31.3 6.4 0.7 238.7 31.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 132.0 0.0 0.0 0.0 54.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.2 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1304.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.2 0.0 IGLV8-61 ENSG00000211638 "Immunoglobulin lambda variable 8-61" A0A075B6I0 22 22098700-22099212 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 805.8;lymphoid tissue: 984.2" "Cell type enriched" "Detected in some" 4 "B-cells: 25.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 3.5" "Group enriched" "Detected in some" 630 "memory B-cell: 257.8;naive B-cell: 529.3" "Lineage enriched" "Detected in single" 848 "B-cells: 529.3" "Cell line enhanced" "Detected in some" "Daudi: 2.2;RPMI-8226: 3.6;SH-SY5Y: 1.8;U-266/70: 6.6" "Low region specificity" "Detected in all" "Immunoglobulin genes" NA NA 620000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.07e-3)" "unprognostic (2.73e-2)" "prognostic favorable (3.84e-4)" "unprognostic (1.07e-2)" "unprognostic (5.24e-2)" "unprognostic (1.04e-3)" "unprognostic (1.65e-1)" "unprognostic (1.75e-3)" "unprognostic (2.05e-1)" "unprognostic (2.11e-1)" "unprognostic (3.32e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (8.14e-2)" "unprognostic (1.31e-1)" "unprognostic (1.08e-1)" "unprognostic (1.90e-1)" 9.4 4.9 0.1 125.5 0.2 63.9 78.3 0.1 3.5 43.5 1.0 201.1 805.8 22.7 0.8 10.6 5.6 46.4 11.7 0.1 0.2 5.3 13.7 82.2 257.2 0.2 0.1 9.2 13.4 1.3 0.8 0.0 0.7 10.5 191.0 0.0 108.6 1.0 0.2 4.0 161.6 13.0 0.8 275.7 179.2 3.3 0.1 16.5 11.5 0.0 984.2 247.8 3.8 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.9 0.4 0.0 0.0 0.0 0.2 3.6 0.0 0.0 1.0 1.8 0.2 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.3 6.6 1.0 0.3 0.0 0.0 0.0 0.2 0.6 0.0 0.2 0.2 0.1 257.8 0.3 0.0 0.4 529.3 0.0 0.0 0.2 0.1 0.4 0.1 0.2 32.7 0.1 0.2 0.1 3.5 0.1 0.2 0.2 0.1 0.7 0.8 0.1 1.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 1.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGSF6 DORA ENSG00000140749 "Immunoglobulin superfamily member 6" O95976 16 21639550-21652608 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 29.8" "Group enriched" "Detected in many" 13 "Hofbauer cells: 216.2;Kupffer cells: 246.9;Langerhans cells: 132.6;Macrophages: 327.1;monocytes: 179.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 1213.7" "Lineage enhanced" "Detected in all" "granulocytes: 1213.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA041023, HPA041072" Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA041023: AB_10794434, HPA041072: AB_10794262" "unprognostic (7.94e-2)" "prognostic favorable (4.92e-4)" "unprognostic (1.18e-2)" "prognostic favorable (1.54e-5)" "unprognostic (3.27e-1)" "unprognostic (4.03e-2)" "unprognostic (2.31e-1)" "unprognostic (1.74e-2)" "unprognostic (1.35e-2)" "unprognostic (6.76e-2)" "unprognostic (1.10e-1)" "unprognostic (6.28e-2)" "unprognostic (8.12e-2)" "unprognostic (1.81e-1)" "unprognostic (4.42e-2)" "unprognostic (1.52e-1)" "unprognostic (2.02e-1)" 2.6 2.3 0.5 13.4 0.6 1.7 1.2 0.8 1.0 1.0 0.7 5.1 1.7 0.4 0.2 0.6 1.1 0.3 0.7 0.6 0.5 0.8 5.5 7.4 3.9 1.0 0.7 0.4 0.9 0.7 0.5 3.3 0.9 0.9 1.5 0.2 2.0 1.6 0.2 0.5 2.7 0.5 0.5 29.8 1.3 0.2 0.6 2.2 0.6 0.9 1.2 2.3 0.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.2 0.1 0.1 0.0 0.5 303.9 46.2 0.7 357.2 0.8 3.8 0.5 0.9 233.9 0.5 0.9 1.2 1213.7 2.7 263.5 55.5 1.0 210.7 0.5 0.6 0.8 1.0 0.6 0.5 1.0 0.7 0.9 0.5 0.6 1.4 1.7 3.2 12.2 0.7 7.1 3.2 0.7 0.0 0.0 1.3 1.4 3.7 4.0 2.8 5.0 1.8 10.4 0.7 15.2 0.0 0.0 0.2 0.4 1.0 1.2 4.0 0.0 6.5 1.1 0.0 1.4 3.2 0.0 2.5 10.1 0.4 2.9 1.8 216.2 0.0 0.8 0.3 0.0 246.9 132.6 0.1 0.9 327.1 8.8 16.9 179.9 0.7 3.1 1.0 0.4 0.0 1.2 0.0 1.3 0.6 0.1 0.4 4.4 2.1 0.0 0.9 1.1 0.1 0.2 0.6 2.0 1.4 5.4 0.2 0.0 0.5 IL17RC IL17-RL ENSG00000163702 "Interleukin 17 receptor C" Q8NAC3 3 9917074-9933630 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.7;myeloid DC: 2.1" "Group enriched" "Detected in many" 18 "dendritic cells: 2.1;monocytes: 1.7" "Cell line enhanced" "Detected in many" "ASC diff: 71.2;ASC TERT1: 43.6;HSkMC: 40.7;T-47d: 41.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019885, CAB026255" Approved "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "CAB026255: , HPA019885: AB_1851664" "unprognostic (2.07e-1)" "unprognostic (2.02e-1)" "unprognostic (1.38e-1)" "prognostic favorable (1.38e-4)" "unprognostic (2.58e-2)" "unprognostic (1.45e-3)" "unprognostic (8.60e-2)" "unprognostic (7.11e-2)" "unprognostic (1.38e-2)" "unprognostic (5.27e-2)" "unprognostic (4.30e-2)" "unprognostic (5.98e-2)" "unprognostic (9.35e-3)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "unprognostic (1.48e-1)" "unprognostic (2.83e-1)" 17.5 32.2 5.5 4.2 5.5 3.8 18.8 5.0 7.1 16.6 6.0 21.4 15.0 15.0 4.9 23.6 14.8 7.4 19.9 5.7 6.6 15.7 63.7 9.2 1.8 6.2 5.9 12.9 15.3 17.0 27.9 2.9 4.9 31.3 4.7 1.1 23.7 12.6 16.9 32.2 15.5 6.9 6.6 5.9 16.8 1.7 7.0 1.9 13.9 15.7 2.4 17.9 19.4 5.0 7.3 4.6 1.5 4.5 71.2 43.6 10.8 10.0 23.4 12.3 19.5 1.6 19.9 0.0 11.8 15.8 8.7 5.1 2.0 10.7 4.1 4.7 6.0 1.9 13.6 6.6 22.0 0.1 0.0 40.7 8.7 14.9 3.3 5.7 10.6 0.0 0.8 9.1 9.8 11.3 0.2 0.4 0.9 2.6 31.4 4.5 5.1 2.6 9.1 4.1 4.0 6.4 6.1 13.7 10.8 0.4 41.2 0.8 8.9 13.4 6.4 5.9 6.7 0.1 0.3 0.0 21.0 0.9 9.8 0.0 1.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.3 5.5 5.5 5.0 7.1 5.7 6.6 6.2 5.9 4.9 6.6 7.0 5.0 10.1 0.0 0.5 18.9 2.0 10.8 18.6 11.2 12.5 2.1 30.2 24.1 3.4 18.6 11.7 1.8 0.0 5.8 2.6 22.4 3.9 15.1 0.5 8.0 8.7 7.8 14.4 6.5 3.8 21.1 4.7 15.7 15.8 10.0 0.0 14.0 11.4 43.9 11.0 1.7 4.8 25.3 16.2 6.0 7.8 1.4 19.0 6.0 14.2 4.7 3.4 25.5 1.0 7.1 0.9 13.2 29.8 17.0 1.7 25.7 53.2 17.7 6.9 1.6 19.7 12.8 12.4 0.8 0.5 13.3 19.9 2.9 2.1 11.9 20.0 16.6 IL17RD "FLJ35755, IL-17RD, IL17RLM, SEF" ENSG00000144730 "Interleukin 17 receptor D" Q8NFM7 3 57089982-57170306 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 28.0" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 14.0;Early spermatids: 17.9;Late spermatids: 23.7;Microglial cells: 15.0;Peritubular cells: 25.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 25.0;AN3-CA: 67.9;NTERA-2: 39.2;SH-SY5Y: 102.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039577, HPA043550" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" Nucleoplasm "HPA039577: AB_2676580, HPA043550: AB_2678546" "unprognostic (4.67e-2)" "unprognostic (1.52e-1)" "unprognostic (2.31e-1)" "unprognostic (2.72e-2)" "unprognostic (1.33e-2)" "unprognostic (9.62e-2)" "unprognostic (1.17e-2)" "unprognostic (1.60e-1)" "unprognostic (3.72e-1)" "unprognostic (2.11e-3)" "unprognostic (4.79e-2)" "unprognostic (1.25e-1)" "prognostic favorable (2.92e-9)" "unprognostic (2.90e-1)" "unprognostic (2.21e-1)" "unprognostic (2.63e-3)" "unprognostic (9.58e-3)" 1.9 0.8 4.7 0.9 5.7 0.0 7.4 5.2 4.0 6.0 28.0 5.9 0.4 13.5 10.6 2.4 6.4 3.3 1.9 5.5 6.5 5.7 0.2 0.6 0.3 8.9 8.8 7.4 0.9 9.4 2.3 0.3 5.5 5.1 1.8 0.3 6.0 8.5 0.6 2.0 1.0 12.0 6.2 2.5 1.2 9.7 4.8 0.3 0.5 2.6 0.5 2.8 3.3 6.5 4.0 0.8 25.0 67.9 0.1 0.6 4.0 0.4 0.2 0.3 0.8 0.5 1.9 0.0 0.2 1.4 5.3 0.2 4.8 1.0 0.8 0.0 1.3 0.0 0.0 0.2 0.1 0.0 0.1 1.0 2.6 0.0 0.5 16.6 1.1 0.6 0.0 0.1 1.4 0.5 0.0 0.1 39.2 2.2 1.9 0.0 9.1 0.0 5.2 1.0 0.6 102.0 1.0 1.5 2.9 8.1 0.9 0.0 0.7 1.3 1.6 1.2 4.2 0.0 0.0 0.1 0.7 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.7 5.7 5.2 4.0 5.5 6.5 8.9 8.8 5.5 6.2 4.8 6.5 1.4 0.0 2.3 11.4 0.0 0.9 2.0 3.1 0.0 0.1 1.5 14.0 1.6 1.5 2.4 0.0 0.0 0.3 0.1 0.1 0.0 3.1 17.9 0.5 5.5 4.0 0.0 0.0 0.6 0.2 0.1 10.1 0.0 1.0 0.0 2.0 1.1 0.1 0.1 0.0 0.9 0.3 2.0 0.0 1.2 23.7 11.5 0.6 0.0 15.0 0.0 0.6 0.0 7.5 2.1 0.7 0.7 25.9 0.0 2.9 0.0 5.0 1.8 0.0 0.0 4.8 1.3 10.6 7.5 1.1 0.9 0.1 0.3 6.5 0.3 0.7 IL17RE FLJ23658 ENSG00000163701 "Interleukin 17 receptor E" Q8NFR9 3 9902612-9916402 "Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.8;skin 1: 31.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 92.6;Gastric mucus-secreting cells: 58.1;Intestinal goblet cells: 52.1;Paneth cells: 37.7;Proximal enterocytes: 74.4;Undifferentiated cells: 40.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 15.5;ASC TERT1: 38.5;hTCEpi: 16.5;T-47d: 19.4" "Region enhanced" "Detected in single" "cerebellum: 1.5" HPA019011 Uncertain "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA019011: AB_1851667" "unprognostic (1.08e-2)" "unprognostic (7.58e-2)" "unprognostic (2.06e-1)" "unprognostic (1.43e-3)" "unprognostic (1.09e-1)" "unprognostic (9.81e-2)" "unprognostic (1.50e-1)" "unprognostic (8.43e-2)" "unprognostic (6.69e-2)" "unprognostic (6.31e-2)" "unprognostic (3.55e-3)" "unprognostic (4.15e-2)" "unprognostic (3.34e-2)" "unprognostic (1.10e-1)" "unprognostic (1.32e-1)" "unprognostic (5.96e-2)" "unprognostic (2.85e-2)" 6.1 0.4 0.5 1.4 1.6 0.0 5.9 2.2 1.0 4.5 0.3 16.6 20.8 1.8 2.7 7.5 2.5 6.8 1.2 0.4 0.9 2.8 0.8 8.1 0.4 1.5 0.4 0.6 9.7 4.2 1.6 1.1 2.3 4.8 13.8 0.1 6.3 3.3 0.4 31.0 20.4 1.4 0.4 1.0 16.7 0.2 0.3 2.8 3.2 0.2 1.7 1.7 6.6 0.4 2.6 0.3 0.0 0.1 15.5 38.5 11.3 1.0 1.4 0.3 0.9 2.9 2.3 0.0 0.6 2.7 0.0 7.1 0.0 6.2 0.1 0.1 0.1 0.8 0.2 6.8 0.4 0.0 3.2 2.4 16.5 0.0 0.1 0.0 0.1 2.5 0.1 0.0 0.7 3.1 0.4 11.3 0.1 8.1 0.8 0.0 0.0 0.1 2.8 3.2 0.6 0.2 0.0 6.5 0.0 0.3 19.4 0.3 1.5 0.1 0.0 0.3 0.2 0.2 0.1 0.0 0.4 6.5 0.2 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.6 2.2 1.0 0.4 0.9 1.5 0.4 2.3 0.4 0.3 0.4 3.4 6.4 1.1 3.3 1.0 14.5 11.9 2.3 14.2 3.0 8.4 8.3 0.9 15.7 2.0 16.5 0.0 4.3 0.8 92.6 7.9 2.7 0.2 1.4 2.0 1.3 33.6 9.0 2.4 4.8 1.8 4.9 58.1 1.3 0.0 1.2 1.8 15.4 2.6 1.7 1.9 52.1 2.0 2.2 3.5 0.4 2.1 1.6 5.4 0.0 1.0 4.7 2.1 2.0 0.6 2.5 37.7 3.4 0.8 6.1 74.4 8.0 1.0 1.0 19.7 1.8 7.2 1.6 2.3 11.8 14.8 0.8 2.8 1.0 40.8 4.6 IL33 "C9orf26, DKFZp586H0523, DVS27, IL1F11, NF-HEV" ENSG00000137033 "Interleukin 33" O95760 9 6215786-6257983 "Predicted intracellular proteins, Predicted secreted proteins" Transcription Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 120.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 141.8;Fibroblasts: 87.5;Hepatic stellate cells: 499.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTERT-RPE1: 53.6;U-2197: 162.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007057, HPA022899, HPA024426" Supported Supported Nucleoplasm,Vesicles "Secreted to blood" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Vesicles "CAB007057: , HPA022899: , HPA024426: AB_1845820" "prognostic favorable (4.42e-4)" "unprognostic (8.36e-2)" "unprognostic (5.67e-3)" "unprognostic (7.67e-3)" "unprognostic (4.27e-1)" "unprognostic (1.63e-1)" "unprognostic (2.59e-3)" "unprognostic (2.66e-3)" "unprognostic (3.18e-1)" "unprognostic (2.05e-1)" "unprognostic (1.43e-1)" "unprognostic (8.08e-2)" "unprognostic (1.58e-3)" "unprognostic (4.70e-3)" "unprognostic (4.10e-2)" "unprognostic (2.64e-1)" "unprognostic (6.85e-3)" 38.7 16.7 9.2 44.6 9.3 0.2 27.2 7.0 12.1 56.2 6.4 24.8 8.8 50.0 15.9 24.5 25.9 33.4 40.9 8.5 10.8 5.0 36.7 53.0 47.1 7.8 8.3 5.0 3.4 3.7 5.7 61.1 7.1 30.0 19.4 2.0 18.9 31.5 6.1 44.0 15.6 50.8 8.3 20.5 33.6 5.8 10.8 13.1 12.6 13.8 43.0 120.7 21.2 8.6 0.0 0.0 0.0 0.0 0.3 1.4 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.1 16.9 0.3 0.0 0.1 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.9 0.7 0.3 0.4 53.6 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.0 0.4 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 162.9 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 9.3 7.0 12.1 8.5 10.8 7.8 8.3 7.1 8.3 10.8 8.6 63.5 6.4 7.2 39.5 1.0 24.2 17.0 73.9 27.3 0.0 9.4 4.1 5.8 4.3 77.8 0.0 0.0 0.0 0.1 2.2 0.0 3.0 0.5 12.4 7.1 141.8 10.7 8.0 0.2 7.9 0.0 87.5 48.4 20.6 1.3 0.0 499.4 5.0 0.1 0.0 0.1 0.2 2.0 20.8 10.2 1.6 20.5 1.7 1.8 1.0 0.0 9.5 0.0 0.5 0.1 12.1 0.2 12.4 0.2 5.2 0.0 0.0 62.1 0.1 0.0 65.5 11.5 0.0 0.4 3.3 48.4 0.1 1.2 0.1 1.1 4.9 INHBC ENSG00000175189 "Inhibin subunit beta C" P55103 12 57434784-57452062 "Plasma proteins, Predicted secreted proteins" "Growth factor, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 172 "liver: 165.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;Hepatocytes: 5.7;Microglial cells: 1.0" "Cancer enriched" "Detected in single" 85 "liver cancer: 22.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 6.4;Karpas-707: 6.3;RH-30: 2.8;U-266/70: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050755 Approved Cytosol "Secreted to blood" NA NA 21000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "HPA050755: " "unprognostic (5.26e-2)" "unprognostic (4.58e-1)" "unprognostic (3.43e-3)" "unprognostic (4.08e-3)" "unprognostic (3.76e-1)" "unprognostic (1.98e-2)" "unprognostic (1.03e-2)" "unprognostic (1.10e-1)" "unprognostic (1.34e-1)" "unprognostic (1.23e-1)" "unprognostic (6.10e-2)" "unprognostic (2.48e-2)" "unprognostic (1.68e-4)" "unprognostic (2.90e-2)" "unprognostic (1.52e-1)" "unprognostic (3.55e-3)" "unprognostic (5.05e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 165.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.1 0.1 0.0 0.0 1.0 0.0 0.2 0.0 6.4 0.0 0.4 0.0 0.1 0.0 0.1 0.4 0.0 0.0 1.6 0.0 6.3 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 2.8 0.5 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.3 0.4 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.7 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IRF6 "LPS, OFC6, VWS, VWS1" ENSG00000117595 "Interferon regulatory factor 6" O14896 1 209785617-209806175 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 95.4;skin 1: 114.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 387.2;Basal prostatic cells: 253.9;Basal squamous epithelial cells: 217.9;Squamous epithelial cells: 251.9;Suprabasal keratinocytes: 552.4;Urothelial cells: 290.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 10.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 61.9;HaCaT: 210.7;HBEC3-KT: 80.5;hTCEpi: 170.1;hTERT-HME1: 82.2;RT4: 78.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA063121, HPA076162" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Cytosol Nucleoplasm "HPA063121: AB_2684942, HPA076162: AB_2686780" "unprognostic (2.59e-1)" "unprognostic (1.79e-3)" "unprognostic (1.74e-1)" "unprognostic (7.80e-2)" "unprognostic (1.33e-2)" "unprognostic (4.94e-3)" "unprognostic (1.46e-1)" "unprognostic (1.36e-1)" "unprognostic (7.82e-2)" "unprognostic (1.46e-1)" "unprognostic (1.74e-3)" "unprognostic (2.03e-1)" "prognostic favorable (0.00e+0)" "unprognostic (2.70e-1)" "unprognostic (2.66e-2)" "unprognostic (2.14e-1)" "unprognostic (4.42e-2)" 1.6 11.4 1.6 3.2 1.5 2.8 35.9 10.9 1.8 21.6 5.2 27.1 26.9 5.9 49.3 95.4 21.7 10.8 29.7 1.7 1.4 17.0 33.3 8.8 0.9 1.9 2.9 1.9 19.7 26.4 6.5 20.4 1.9 32.4 31.5 2.4 39.0 26.4 0.5 114.0 25.0 2.0 2.1 2.1 24.8 2.9 2.3 20.3 17.1 2.7 23.0 40.5 46.8 1.2 61.9 0.0 0.0 0.0 0.4 0.0 20.9 0.1 0.5 0.1 0.3 13.6 20.7 0.0 0.1 0.1 0.0 210.7 0.0 80.5 0.0 0.0 1.3 0.1 0.2 0.0 0.2 0.0 0.2 0.1 170.1 0.1 82.2 0.0 3.7 0.0 0.1 0.2 0.0 8.3 0.0 0.3 1.2 17.0 0.2 0.0 0.0 0.3 7.7 78.8 18.7 6.1 1.4 34.1 1.9 3.8 24.1 0.3 0.0 0.0 0.1 0.0 0.3 0.8 15.8 0.1 0.2 0.0 0.2 0.0 0.0 0.4 0.6 0.2 0.4 0.1 0.1 0.2 0.1 0.1 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.2 1.6 1.5 10.9 1.8 1.7 1.4 1.9 2.9 1.9 2.1 2.3 1.2 1.9 16.0 10.4 0.3 1.0 387.2 253.9 154.0 217.9 0.1 47.2 33.3 26.0 32.9 70.4 35.0 0.0 94.2 1.3 95.5 27.4 36.7 1.1 120.2 9.5 6.0 59.9 0.4 0.0 19.2 25.4 4.5 53.0 121.7 2.5 0.0 1.1 35.9 8.3 0.0 0.1 74.9 38.7 1.0 30.1 0.7 0.6 2.3 35.6 1.9 1.0 6.5 0.0 0.0 0.0 49.2 43.8 0.0 2.5 153.9 49.5 11.9 82.1 0.6 0.0 0.4 7.4 8.2 3.7 251.9 552.4 161.6 2.5 0.7 44.5 290.3 ITGBL1 "OSCP, TIED" ENSG00000198542 "Integrin subunit beta like 1" O95965 13 101452593-101720856 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Fibroblasts: 76.1;Skeletal myocytes: 93.0" "Cancer enhanced" "Detected in many" "pancreatic cancer: 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 208.3;ASC TERT1: 138.7;fHDF/TERT166: 345.3;LHCN-M2: 311.8" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 12 "spinal cord: 56.9" "Secreted - unknown location" NA NA 37000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.70e-1)" "unprognostic (2.12e-2)" "unprognostic (1.59e-2)" "unprognostic (1.55e-2)" "unprognostic (2.12e-4)" "unprognostic (1.45e-1)" "unprognostic (3.18e-1)" "unprognostic (2.54e-1)" "unprognostic (1.86e-1)" "unprognostic (8.84e-2)" "unprognostic (2.16e-2)" "unprognostic (9.50e-2)" "unprognostic (1.13e-5)" "unprognostic (1.44e-2)" "unprognostic (2.55e-1)" "unprognostic (1.68e-1)" "prognostic unfavorable (2.70e-4)" 16.9 9.2 1.8 0.7 1.8 0.1 18.0 2.6 2.3 23.8 2.5 1.5 0.5 2.0 0.5 9.7 4.9 38.3 18.3 1.9 3.6 2.7 7.7 25.4 1.3 3.9 2.3 5.3 7.9 5.6 10.3 33.4 4.3 4.0 2.5 0.1 11.7 4.4 4.5 13.2 0.5 4.1 3.5 4.0 7.2 2.5 2.2 0.9 8.4 14.9 4.3 17.8 10.0 6.5 4.2 0.3 0.0 0.0 208.3 138.7 0.0 65.8 67.7 29.3 18.7 0.0 2.4 0.0 0.3 345.3 13.9 70.9 0.0 24.1 46.0 0.0 0.0 21.3 0.6 0.0 21.7 0.0 0.0 59.3 1.5 16.8 46.6 55.3 76.8 0.0 1.5 0.7 311.8 0.0 0.0 0.0 0.0 0.0 24.0 0.1 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 8.8 24.0 33.2 27.3 0.1 8.3 0.0 0.0 50.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.8 2.6 2.3 1.9 3.6 3.9 2.3 4.3 3.5 2.2 6.5 1.9 3.2 0.5 5.5 0.1 4.0 0.1 1.3 0.6 1.8 4.2 19.0 0.5 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.5 4.5 0.5 7.7 1.2 0.0 0.0 3.6 0.2 0.8 76.1 5.6 1.1 0.0 0.0 8.6 0.5 0.7 5.0 6.7 0.0 0.0 0.0 4.7 2.1 0.0 0.8 5.4 13.1 0.0 0.5 0.0 2.0 5.0 1.1 0.0 8.2 0.6 0.2 0.0 0.1 0.0 0.7 0.0 93.0 4.8 11.6 8.4 0.7 2.4 0.8 0.4 1.2 0.0 0.2 ITPR2 "CFAP48, IP3R2" ENSG00000123104 "Inositol 1,4,5-trisphosphate receptor type 2" Q14571 12 26335352-26833194 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 44.3" "Cell type enhanced" "Detected in many" "Astrocytes: 551.4;Excitatory neurons: 287.2;Microglial cells: 802.9;Oligodendrocyte precursor cells: 441.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 32.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 62.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059144, HPA062260" Uncertain Supported "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Endoplasmic reticulum" Nucleoplasm "HPA059144: AB_2683925, HPA062260: AB_2684728" "unprognostic (5.65e-2)" "unprognostic (1.46e-1)" "unprognostic (1.22e-1)" "unprognostic (4.53e-1)" "unprognostic (2.25e-1)" "unprognostic (2.37e-2)" "unprognostic (3.59e-3)" "unprognostic (8.70e-2)" "unprognostic (1.66e-1)" "unprognostic (8.61e-2)" "unprognostic (2.06e-2)" "unprognostic (1.63e-1)" "unprognostic (1.54e-2)" "unprognostic (2.82e-1)" "unprognostic (9.13e-2)" "unprognostic (3.99e-2)" "unprognostic (3.76e-1)" 8.3 10.4 10.5 8.1 7.3 6.0 17.3 6.3 9.7 4.8 3.4 6.2 5.3 5.2 5.7 7.4 5.5 5.5 3.7 7.7 8.7 12.6 44.3 5.6 7.9 19.1 13.2 5.9 7.7 11.4 2.2 10.9 14.9 5.5 6.6 8.8 16.9 2.9 1.8 10.2 4.9 4.5 13.1 6.7 5.2 2.5 16.1 20.1 4.3 4.1 6.8 4.9 4.7 15.6 4.9 2.0 2.9 4.6 8.5 8.6 3.0 4.4 6.1 3.0 3.1 0.2 2.4 16.5 2.7 5.9 3.3 5.2 15.1 9.3 4.0 3.9 5.1 13.5 4.4 27.1 7.9 12.0 5.8 8.1 1.2 6.3 11.6 6.2 28.5 6.5 6.4 5.1 3.9 4.0 8.6 17.8 12.2 4.4 1.5 2.9 7.0 10.7 7.3 7.4 0.9 4.5 19.8 3.5 11.4 11.3 7.7 6.0 62.6 6.0 2.3 5.9 5.7 4.9 4.2 31.2 5.7 5.6 3.9 32.4 6.4 9.9 2.9 2.7 2.5 5.4 2.6 2.4 1.4 5.0 3.0 2.7 17.3 4.8 4.3 11.9 4.4 1.0 10.5 7.3 6.3 9.7 7.7 8.7 19.1 13.2 14.9 13.1 16.1 15.6 27.1 48.1 52.9 551.4 45.7 20.9 17.8 3.3 31.3 3.2 87.0 57.1 24.5 34.3 8.6 23.9 146.0 21.0 39.1 7.7 7.9 20.8 3.1 13.3 64.9 38.5 78.5 33.4 287.2 23.4 9.5 20.3 16.8 22.7 44.4 60.0 25.0 123.7 39.5 0.0 99.1 46.1 32.6 46.3 8.2 6.7 18.0 68.7 33.8 802.9 28.2 13.0 41.2 441.8 22.3 17.6 37.0 17.7 83.6 25.9 14.5 14.6 5.0 64.7 0.0 22.7 17.6 3.6 6.3 54.3 26.7 27.9 29.2 43.4 11.7 15.8 JAM2 "C21orf43, CD322, JAM-B, JAMB, VE-JAM" ENSG00000154721 "Junctional adhesion molecule 2" P57087 21 25639258-25717562 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 63.5" "Cell type enhanced" "Detected in many" "Adipocytes: 173.8;Astrocytes: 81.6;Endothelial cells: 148.7;Hepatic stellate cells: 112.8;Microglial cells: 82.4;Oligodendrocyte precursor cells: 76.9" "Cancer enriched" "Detected in all" 9 "glioma: 27.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 25.5;BJ hTERT+: 16.5;HDLM-2: 16.7;hTERT-RPE1: 22.5;U-138 MG: 18.1;U-87 MG: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028789, HPA077346" Supported "Nucleoplasm,Plasma membrane" NA NA 360000 "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoplasm "HPA028789: AB_2732443, HPA077346: AB_2732341" "unprognostic (1.42e-1)" "unprognostic (6.39e-2)" "unprognostic (1.23e-1)" "unprognostic (1.73e-1)" "unprognostic (2.02e-2)" "unprognostic (1.53e-2)" "unprognostic (7.51e-4)" "unprognostic (2.61e-2)" "unprognostic (4.55e-1)" "unprognostic (1.02e-1)" "unprognostic (3.46e-2)" "unprognostic (3.81e-1)" "unprognostic (8.86e-2)" "unprognostic (5.71e-3)" "unprognostic (2.18e-1)" "unprognostic (2.20e-1)" "unprognostic (4.85e-3)" 20.5 15.8 16.6 3.7 21.5 0.3 16.8 24.0 21.8 16.8 12.8 17.8 6.1 18.5 11.2 7.1 16.1 12.9 19.2 19.2 22.0 9.2 2.2 15.5 3.6 25.9 23.1 16.1 2.8 4.3 8.1 63.5 21.3 9.4 7.9 7.1 6.1 15.4 7.8 5.5 10.7 19.6 26.8 1.6 10.2 17.6 25.2 2.6 10.3 13.2 5.0 11.6 13.2 23.0 0.0 0.0 25.5 0.1 1.0 0.2 0.5 0.8 16.5 2.0 7.6 0.0 0.0 0.1 0.0 0.2 9.7 0.1 2.2 0.0 4.6 16.7 0.7 0.1 0.1 0.1 0.0 0.1 0.1 1.4 0.0 1.8 0.1 22.5 0.0 0.6 0.0 0.2 8.0 0.0 0.4 0.1 8.1 0.2 0.0 3.2 5.3 0.1 0.0 0.0 0.4 3.7 0.2 0.3 0.0 0.3 0.9 0.2 0.0 18.1 1.7 0.1 2.5 1.8 0.1 0.0 13.4 0.1 0.7 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.6 0.1 0.2 0.4 0.6 0.1 0.4 0.0 0.1 16.6 21.5 24.0 21.8 19.2 22.0 25.9 23.1 21.3 26.8 25.2 23.0 173.8 0.0 2.3 81.6 0.9 7.5 1.4 0.0 2.2 1.4 1.4 9.1 33.2 0.0 0.0 3.7 14.6 0.3 0.5 0.0 0.0 0.2 16.5 1.0 4.7 148.7 0.0 0.0 15.2 0.2 5.3 28.5 0.5 2.1 0.0 4.5 112.8 0.5 1.3 0.0 45.0 0.0 0.0 1.8 10.7 15.6 9.9 2.8 16.0 82.4 0.0 1.8 0.0 76.9 4.1 0.1 0.0 24.5 1.2 1.5 0.0 0.0 0.7 5.2 0.0 5.7 7.0 6.7 4.4 0.8 6.7 0.8 1.6 2.1 0.0 1.2 JCHAIN "IGCJ, IGJ, JCH" ENSG00000132465 "Joining chain of multimeric IgA and IgM" P01591 4 70655541-70681817 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 3028.0;intestine: 7979.6;stomach 1: 5916.2" "Cell type enriched" "Detected in many" 16 "Plasma cells: 101294.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 121 "memory B-cell: 4173.0;naive B-cell: 2555.1;plasmacytoid DC: 3578.1" "Group enriched" "Detected in all" 137 "B-cells: 4173.0;dendritic cells: 3578.1" "Cell line enhanced" "Detected in many" "Daudi: 3953.8;Karpas-707: 2117.6;RPMI-8226: 4469.2;U-266/70: 8794.0;U-266/84: 3519.2;U-698: 4949.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034436, HPA044132" Enhanced "Secreted to blood" NA NA 2200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 9: Intestine - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB034436: AB_2233368, HPA044132: AB_2678826" "prognostic favorable (1.81e-6)" "unprognostic (1.45e-3)" "unprognostic (7.44e-3)" "unprognostic (1.82e-2)" "unprognostic (4.23e-2)" "prognostic favorable (7.56e-7)" "unprognostic (2.37e-2)" "unprognostic (2.70e-2)" "unprognostic (6.30e-2)" "unprognostic (2.64e-3)" "unprognostic (3.36e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (3.43e-1)" "unprognostic (3.03e-2)" "unprognostic (2.22e-1)" "unprognostic (1.96e-1)" 130.2 76.6 0.7 1089.0 0.8 76.3 3028.0 0.4 3.0 205.2 3.1 7979.6 6145.8 94.2 25.0 654.4 115.0 492.4 45.6 0.4 1.4 43.3 116.8 620.2 1033.5 1.9 1.0 183.5 78.3 2.1 2.0 2.4 0.8 90.2 6426.5 0.3 2420.5 258.4 4.2 13.2 4277.1 200.3 7.0 819.4 5916.2 40.0 0.8 155.3 19.4 0.8 1746.7 1059.4 11.6 2.8 8.9 0.0 0.0 0.0 0.0 0.0 15.5 8.2 1.5 0.1 0.1 0.0 0.0 3953.8 3.3 12.7 0.1 6.6 0.0 0.0 0.6 2.1 0.0 3.3 0.0 0.0 0.0 3.3 9.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 5.4 2117.6 0.1 0.0 6.1 14.9 4.9 0.0 0.0 4.8 2.6 4469.2 0.0 0.0 3.3 15.7 3.7 2.6 2.7 0.0 0.8 6.8 3.9 9.9 11.8 4.9 6.3 8794.0 3519.2 4949.0 2.1 5.2 1.2 25.1 7.5 2.6 4.0 1.5 19.1 4173.0 2.5 3.8 6.6 2555.1 2.1 2.1 28.3 4.5 2.5 3578.1 2.6 1310.4 0.7 0.8 0.4 3.0 0.4 1.4 1.9 1.0 0.8 7.0 0.8 2.8 3.0 22.4 101.3 0.0 6154.9 0.0 28.2 0.0 8.6 0.0 11.7 1.9 2.2 15.7 8.1 0.0 0.0 0.1 700.0 5.1 0.0 0.0 0.5 0.0 0.1 38.1 7.3 139.0 0.0 0.0 0.1 48.8 228.8 0.0 79.5 0.1 66.4 24.6 0.3 0.0 0.0 5.3 0.0 35.8 0.0 0.3 0.0 42.0 0.0 0.0 3.9 0.0 6.2 0.0 0.0 0.0 5.1 0.0 101294.9 32.7 0.0 5.4 3.6 0.0 0.0 0.6 88.4 1.4 0.3 24.3 0.0 0.3 1487.8 0.0 3.5 0.6 KANK3 "ANKRD47, FLJ46061" ENSG00000186994 "KN motif and ankyrin repeat domains 3" Q6NY19 19 8322584-8343262 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 196.2;Endothelial cells: 83.8;Hepatic stellate cells: 55.3" "Cancer enhanced" "Detected in all" "testis cancer: 7.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 4 "NK-cells: 1.2;T-cells: 1.0" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 8.1;TIME: 14.8;U-266/70: 5.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "olfactory bulb: 16.2" HPA051153 Approved Approved "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA051153: AB_2681365" "unprognostic (1.56e-1)" "unprognostic (1.63e-4)" "unprognostic (1.54e-2)" "unprognostic (8.95e-3)" "unprognostic (1.07e-1)" "unprognostic (2.84e-3)" "unprognostic (1.82e-3)" "unprognostic (3.26e-2)" "unprognostic (1.19e-1)" "unprognostic (1.39e-2)" "unprognostic (1.34e-2)" "unprognostic (4.77e-1)" "prognostic favorable (1.69e-5)" "unprognostic (5.03e-2)" "unprognostic (1.67e-1)" "unprognostic (2.86e-1)" "unprognostic (3.24e-1)" 25.6 7.6 12.0 2.3 9.7 0.6 26.1 9.6 12.2 8.2 5.8 6.2 2.9 10.2 0.7 5.1 11.2 2.5 32.9 8.7 8.9 22.2 4.2 33.4 2.8 12.5 11.5 3.6 3.9 1.5 6.9 14.6 11.5 7.6 0.5 0.3 4.1 1.8 13.7 6.7 7.3 2.4 9.7 35.5 6.2 2.4 13.2 0.7 15.5 6.0 0.8 7.9 6.8 8.9 0.1 0.6 0.2 0.5 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.7 0.2 0.0 2.3 0.0 0.0 0.1 0.5 2.6 0.0 0.7 1.4 0.3 0.3 0.4 0.1 0.2 1.3 0.0 0.8 0.0 0.0 0.0 8.1 0.6 0.0 0.3 0.0 0.4 0.0 0.4 0.5 0.5 0.2 1.4 0.0 0.7 0.1 0.1 0.0 0.1 0.0 0.7 0.1 0.0 0.5 0.0 14.8 0.0 1.3 0.3 0.1 5.9 0.2 0.3 0.1 0.1 0.2 0.2 0.1 0.0 1.0 0.0 0.5 0.1 0.5 0.1 0.0 0.1 0.2 0.4 0.2 1.2 0.0 0.0 0.4 0.2 12.0 9.7 9.6 12.2 8.7 8.9 12.5 11.5 11.5 9.7 13.2 8.9 196.2 6.4 3.2 2.0 0.3 2.5 0.4 0.6 0.6 0.3 1.5 2.5 2.2 0.0 0.8 0.0 4.2 0.4 3.8 0.1 5.9 0.1 6.6 0.5 0.7 83.8 0.0 2.7 0.6 1.8 0.3 6.4 1.5 0.8 0.0 0.2 55.3 1.0 0.5 0.0 0.9 0.0 0.0 1.3 2.1 8.1 0.6 0.9 5.4 18.7 0.0 0.4 12.3 0.5 1.6 0.6 0.1 0.4 0.4 1.0 0.0 0.4 0.7 0.7 19.7 8.3 12.9 6.5 3.6 1.1 1.3 0.3 2.8 4.0 0.1 0.8 KAZN "C1orf196, FLJ43806, KAZRIN, KIAA1026" ENSG00000189337 "Kazrin, periplakin interacting protein" Q674X7 1 13892792-15118043 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 91.5" "Group enriched" "Detected in many" 12 "Excitatory neurons: 1065.9;Inhibitory neurons: 2872.7;Oligodendrocyte precursor cells: 1360.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 23 "neutrophil: 3.4" "Lineage enriched" "Detected in single" 23 "granulocytes: 3.4" "Cell line enhanced" "Detected in many" "AN3-CA: 85.6;SK-BR-3: 46.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032095, HPA032096" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear speckles, Cytosol" "HPA032095: AB_2674146, HPA032096: AB_10670826" "unprognostic (2.81e-1)" "unprognostic (5.82e-2)" "unprognostic (1.12e-1)" "unprognostic (2.42e-3)" "unprognostic (5.34e-2)" "unprognostic (2.15e-3)" "unprognostic (6.57e-3)" "unprognostic (7.88e-3)" "unprognostic (3.21e-1)" "unprognostic (4.96e-3)" "unprognostic (1.10e-1)" "unprognostic (5.55e-2)" "prognostic favorable (1.20e-6)" "unprognostic (3.61e-2)" "unprognostic (7.93e-2)" "unprognostic (3.21e-1)" "unprognostic (1.06e-2)" 12.6 17.7 27.3 3.0 31.5 0.6 11.4 43.6 33.6 17.0 23.9 5.5 5.1 4.2 12.2 34.9 12.6 7.7 6.9 25.0 24.1 24.9 5.8 16.5 1.0 37.1 32.9 16.7 9.2 29.5 5.1 6.3 32.7 7.5 3.9 12.9 21.4 7.4 1.4 23.5 5.3 3.6 29.2 91.5 5.1 4.5 34.1 1.9 10.3 1.6 5.5 8.9 21.3 47.1 17.7 3.0 18.5 85.6 7.9 8.2 6.3 8.3 6.9 15.0 10.8 4.0 9.3 0.0 21.1 17.8 2.7 6.3 4.3 13.5 7.5 0.5 8.4 10.1 10.2 26.6 5.8 0.0 5.0 11.6 17.7 3.5 2.3 6.8 0.1 2.5 4.2 19.8 12.2 12.8 0.1 1.1 5.1 7.9 2.6 6.0 0.4 10.6 25.5 5.4 9.8 7.1 1.5 46.3 33.0 10.5 2.8 6.7 0.0 12.4 11.6 19.8 10.1 3.3 3.0 0.0 11.6 17.4 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 27.3 31.5 43.6 33.6 25.0 24.1 37.1 32.9 32.7 29.2 34.1 47.1 17.6 3.2 1.8 124.1 0.9 50.3 16.6 9.7 31.3 12.4 23.0 27.9 3.4 4.3 9.1 49.7 8.4 1.5 0.9 12.3 17.6 2.0 6.8 51.4 15.8 19.4 7.1 0.0 1065.9 1.6 8.1 27.0 3.6 16.8 3.8 9.7 31.1 0.1 0.8 0.0 2872.7 5.2 18.3 0.9 11.4 9.1 19.0 1.1 46.2 93.7 0.0 74.2 4.1 1360.7 143.5 1.5 1.6 17.3 0.3 19.4 2.0 12.9 30.3 3.2 6.6 33.5 23.6 0.3 3.2 26.2 90.4 46.4 1.4 41.6 3.5 24.8 KCND3 "KSHIVB, Kv4.3, SCA19, SCA22" ENSG00000171385 "Potassium voltage-gated channel subfamily D member 3" Q9UK17 1 111770662-111989668 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Brugada syndrome, Disease variant, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 46.8;Cardiomyocytes: 38.1;Excitatory neurons: 105.7;Hepatocytes: 37.8;Inhibitory neurons: 88.4;Oligodendrocyte precursor cells: 45.8" "Cancer enhanced" "Detected in many" "prostate cancer: 8.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 4.8;SCLC-21H: 10.1;U-2 OS: 1.6;WM-115: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029452 Approved NA NA "Cluster 15: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA029452: AB_10602239" "unprognostic (1.11e-2)" "unprognostic (1.73e-3)" "unprognostic (1.71e-1)" "unprognostic (2.60e-2)" "unprognostic (1.37e-1)" "unprognostic (2.42e-1)" "unprognostic (1.41e-1)" "unprognostic (9.48e-2)" "unprognostic (1.15e-1)" "unprognostic (9.17e-2)" "unprognostic (1.86e-2)" "unprognostic (1.40e-1)" "unprognostic (7.44e-2)" "unprognostic (3.64e-1)" "unprognostic (1.23e-1)" "unprognostic (2.51e-3)" "unprognostic (6.64e-3)" 4.5 1.5 17.0 4.7 13.8 0.2 3.0 18.1 17.9 2.3 0.0 5.9 0.9 5.3 12.6 4.1 5.1 5.5 8.4 16.2 6.4 1.3 15.4 1.7 0.5 1.0 35.6 0.5 4.5 3.9 3.4 0.5 3.4 11.3 2.4 12.7 1.6 12.0 2.6 7.1 2.2 9.8 0.9 3.2 3.3 2.0 9.2 0.3 1.1 1.7 0.5 5.9 3.2 10.8 0.0 0.0 0.2 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 1.0 0.4 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.2 4.8 0.0 0.0 0.0 0.0 0.0 0.2 10.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 17.0 13.8 18.1 17.9 16.2 6.4 1.0 35.6 3.4 0.9 9.2 10.8 1.1 0.0 9.3 18.3 0.3 7.5 11.9 2.9 0.0 46.8 7.8 1.5 38.1 0.0 1.5 0.0 4.2 0.1 0.4 1.5 0.0 0.8 35.7 0.5 14.5 1.6 0.0 2.7 105.7 23.8 0.2 3.7 0.0 0.7 0.0 0.0 1.8 37.8 0.2 30.3 88.4 0.4 4.1 0.8 1.9 32.3 18.0 0.5 3.6 1.0 0.0 6.2 0.0 45.8 8.7 4.8 1.2 1.9 0.0 21.9 0.1 0.3 0.1 4.8 0.0 0.8 1.7 1.5 1.0 2.0 6.7 0.0 0.5 0.1 2.4 13.4 KCNJ10 "Kir1.2, Kir4.1" ENSG00000177807 "Potassium inwardly rectifying channel subfamily J member 10" P78508 1 159998651-160070160 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Deafness, Disease variant, Epilepsy, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 100.7;kidney: 28.0;retina: 36.7" "Group enriched" "Detected in some" 5 "Astrocytes: 93.0;Muller glia cells: 75.7;Oligodendrocyte precursor cells: 35.7;Oligodendrocytes: 93.7" "Cancer enriched" "Detected in some" 6 "glioma: 27.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 6.7;SK-MEL-30: 2.1;U-266/70: 2.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078302 Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 5: Muller glia cells - Visual perception" "HPA078302: AB_2732378" "unprognostic (2.64e-2)" "unprognostic (3.54e-3)" "unprognostic (6.19e-2)" "unprognostic (1.33e-1)" "unprognostic (2.84e-1)" "unprognostic (6.98e-4)" "unprognostic (1.96e-1)" "unprognostic (7.13e-2)" "unprognostic (3.43e-1)" "unprognostic (1.28e-3)" "unprognostic (5.80e-4)" "unprognostic (9.52e-2)" "unprognostic (2.09e-2)" "unprognostic (2.08e-2)" "unprognostic (1.41e-1)" "unprognostic (3.77e-1)" "unprognostic (6.70e-3)" 0.1 0.3 56.7 2.1 86.3 0.0 0.1 100.2 58.4 0.2 8.7 0.5 0.2 0.1 0.0 0.1 0.1 0.1 0.1 51.4 78.7 28.0 2.1 0.1 7.3 92.7 94.7 0.1 0.1 0.1 0.4 0.0 87.5 0.2 0.2 36.7 0.3 0.2 0.1 0.4 0.5 0.0 71.8 10.5 0.9 0.6 83.6 0.4 0.2 0.1 1.9 0.1 0.1 100.7 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.2 0.0 0.1 1.0 0.1 0.0 0.6 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 1.2 0.1 0.0 0.0 0.1 0.2 0.0 0.1 2.1 0.5 0.0 0.3 0.1 0.0 0.2 0.5 0.0 2.0 1.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.6 0.0 56.7 86.3 100.2 58.4 51.4 78.7 92.7 94.7 87.5 71.8 83.6 100.7 0.1 0.0 0.0 93.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.5 0.0 0.0 3.7 4.2 0.0 0.0 0.0 11.7 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 13.0 0.0 1.1 0.0 1.1 0.0 3.7 0.0 75.7 0.0 35.7 93.7 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 3.5 0.0 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KDF1 "C1orf172, FLJ34633, RP11-344H11.3" ENSG00000175707 "Keratinocyte differentiation factor 1" Q8NAX2 1 26949562-26960468 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 32.6;Ductal cells: 29.4;Syncytiotrophoblasts: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 36 "B-cells: 3.4;T-cells: 6.2" "Cell line enhanced" "Detected in some" "A-431: 24.9;BEWO: 20.8;CAPAN-2: 22.7;HaCaT: 21.4;HBEC3-KT: 30.3;hTCEpi: 38.5;OE19: 39.3;SK-BR-3: 25.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA028634, HPA028639" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 30: Epithelial cell lines - Translation" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" Cytosol "HPA028634: , HPA028639: AB_10599191" "unprognostic (2.58e-1)" "unprognostic (1.23e-1)" "unprognostic (6.46e-2)" "unprognostic (1.50e-2)" "unprognostic (1.15e-2)" "unprognostic (1.05e-1)" "unprognostic (1.64e-1)" "unprognostic (8.45e-2)" "unprognostic (9.09e-2)" "unprognostic (9.01e-2)" "unprognostic (2.73e-1)" "unprognostic (3.91e-1)" "prognostic favorable (3.04e-13)" "unprognostic (1.38e-3)" "unprognostic (7.83e-2)" "unprognostic (8.03e-2)" "prognostic favorable (4.40e-4)" 0.1 1.1 0.4 1.3 0.3 0.1 10.3 1.6 1.3 4.0 0.3 8.9 12.4 0.9 19.7 20.2 7.4 2.9 0.4 0.4 0.2 11.0 4.7 4.4 0.8 0.3 0.3 0.1 16.2 12.5 10.4 3.9 0.4 7.2 7.1 1.3 12.8 4.6 0.0 17.7 10.5 0.3 0.2 0.6 10.6 2.6 0.3 2.3 10.0 0.0 3.4 4.8 8.3 0.7 24.9 0.0 0.0 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 12.1 22.7 0.0 0.9 0.0 0.0 21.4 0.0 30.3 0.0 0.1 0.4 0.0 0.0 4.4 0.3 0.0 0.0 0.1 38.5 0.0 3.1 0.0 0.0 0.0 1.4 0.0 0.0 14.7 0.0 0.1 1.7 39.3 0.1 0.0 0.0 3.7 5.5 11.7 14.9 0.0 0.2 25.2 0.1 2.7 16.1 0.4 0.2 0.0 0.0 0.0 0.0 2.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 3.2 2.5 4.3 3.0 0.1 3.4 6.2 3.8 0.0 0.0 0.0 0.0 0.2 1.7 0.4 0.3 1.6 1.3 0.4 0.2 0.3 0.3 0.4 0.2 0.3 0.7 0.2 12.8 8.8 0.0 0.8 0.0 14.3 0.0 10.8 0.6 15.1 16.3 0.3 12.8 2.5 14.7 0.0 32.6 1.5 17.2 25.4 29.4 0.4 7.3 0.8 0.7 7.8 0.0 0.2 23.2 26.5 0.6 13.7 8.0 0.0 0.1 0.0 4.4 2.7 0.0 0.1 13.1 0.0 0.3 0.0 0.1 0.3 0.1 0.0 0.0 0.2 1.1 0.0 0.0 0.1 21.8 25.2 0.0 0.4 16.8 26.2 10.1 5.1 2.5 0.0 0.0 0.3 6.3 7.5 14.4 0.0 29.7 1.2 0.0 16.9 19.0 KDR "CD309, FLK1, VEGFR, VEGFR2" ENSG00000128052 "Kinase insert domain receptor" P35968 4 55078481-55125595 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 9 "Adipocytes: 157.8;Endothelial cells: 143.8;Hepatic stellate cells: 158.1;Muller glia cells: 206.6" "Cancer enhanced" "Detected in all" "renal cancer: 27.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 74.8;TIME: 83.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004028, HPA073577" Enhanced Approved "Nuclear membrane,Vesicles" "Intracellular and membrane" NA NA 11000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Nuclear membrane" "CAB004028: AB_2212507, HPA073577: " "unprognostic (1.61e-1)" "unprognostic (2.03e-1)" "unprognostic (9.65e-2)" "unprognostic (1.97e-1)" "unprognostic (9.63e-2)" "unprognostic (1.22e-2)" "unprognostic (1.78e-3)" "unprognostic (2.59e-2)" "unprognostic (1.19e-2)" "unprognostic (1.10e-1)" "unprognostic (8.79e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (7.26e-4)" "unprognostic (4.00e-2)" "unprognostic (2.30e-1)" "unprognostic (3.22e-1)" "unprognostic (1.86e-1)" 41.6 11.7 2.7 4.3 3.8 0.0 26.1 2.8 4.1 14.8 10.4 6.3 2.2 39.5 2.9 4.0 17.9 5.6 20.6 2.1 2.8 15.7 9.2 23.5 2.8 3.2 3.6 5.2 6.2 8.6 11.0 30.9 3.5 11.7 1.0 16.4 5.3 10.0 6.5 5.9 7.5 7.5 3.3 4.4 8.4 1.8 4.5 1.0 34.4 4.6 1.0 8.6 7.5 3.4 0.0 0.0 4.4 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 8.5 0.0 0.0 0.9 0.0 0.0 0.4 0.2 74.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.4 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.8 2.8 4.1 2.1 2.8 3.2 3.6 3.5 3.3 4.5 3.4 157.8 0.0 4.9 0.0 1.4 2.5 0.5 0.1 1.8 11.7 1.3 2.5 9.4 1.5 18.4 0.0 0.0 0.1 0.8 0.0 0.0 0.5 0.8 0.4 2.6 143.8 0.0 2.7 0.1 0.0 0.1 8.3 0.0 0.8 2.5 0.0 158.1 3.3 0.4 0.0 1.3 0.0 0.0 10.6 2.1 0.9 0.0 1.2 7.2 7.5 0.0 206.6 0.0 0.0 6.1 0.5 0.0 0.4 1.3 0.5 0.0 0.0 3.9 7.9 0.0 0.9 7.5 0.3 0.9 0.8 2.7 0.1 0.6 1.6 0.0 1.4 KIAA1671 ENSG00000197077 KIAA1671 Q9BY89 22 24952730-25197448 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 74.4;Excitatory neurons: 67.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.8" "Lineage enriched" "Detected in single" 4 "T-cells: 1.8" "Cell line enhanced" "Detected in many" "OE19: 39.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018135 Approved Approved Microtubules NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Microtubules "HPA018135: AB_1859551" "unprognostic (1.67e-1)" "unprognostic (1.65e-3)" "unprognostic (1.14e-2)" "unprognostic (1.46e-2)" "unprognostic (7.34e-2)" "unprognostic (3.52e-2)" "unprognostic (8.71e-3)" "unprognostic (1.26e-2)" "unprognostic (1.21e-1)" "unprognostic (2.47e-1)" "unprognostic (2.66e-2)" "unprognostic (7.68e-2)" "prognostic favorable (3.19e-6)" "unprognostic (6.72e-2)" "unprognostic (1.14e-1)" "unprognostic (7.54e-2)" "unprognostic (7.87e-2)" 10.7 13.7 12.4 5.1 13.2 0.8 22.5 2.8 17.9 10.3 8.6 16.0 14.4 6.6 5.2 25.9 20.0 14.8 11.3 20.0 7.7 11.0 34.1 12.2 5.5 6.7 8.3 8.5 10.1 10.3 11.2 4.1 3.9 13.2 14.2 15.5 25.9 15.5 25.1 28.0 16.8 6.8 6.5 3.8 12.4 4.9 13.5 15.6 26.6 22.1 8.9 8.9 18.7 5.6 25.2 15.7 3.3 5.9 0.1 0.1 2.6 0.1 0.1 1.4 0.1 12.6 9.0 0.1 11.7 1.1 6.9 29.8 25.5 25.2 1.0 0.2 10.6 0.1 16.7 16.9 3.3 0.1 1.3 0.6 22.4 7.9 24.3 16.6 28.9 0.5 0.3 0.1 3.4 11.6 0.1 0.1 5.2 39.9 8.3 1.1 26.6 4.9 16.3 10.8 8.0 6.7 20.3 14.0 1.3 10.8 7.6 0.2 19.5 1.4 27.0 16.6 4.5 0.1 0.4 0.1 10.0 0.0 4.3 0.2 0.0 0.0 1.8 0.0 0.2 0.0 0.5 1.3 0.0 0.1 0.2 0.8 0.2 0.4 0.0 0.1 0.1 0.3 12.4 13.2 2.8 17.9 20.0 7.7 6.7 8.3 3.9 6.5 13.5 5.6 27.7 12.8 21.9 74.4 1.1 10.8 21.1 16.2 18.2 4.2 25.4 16.5 11.9 25.8 19.2 5.5 22.9 0.2 3.0 62.9 0.0 18.9 2.6 31.2 3.5 28.5 7.2 5.3 67.8 18.9 0.1 4.9 22.4 30.2 1.3 4.2 29.6 47.8 2.4 16.8 22.9 12.3 6.1 1.9 5.9 3.5 7.2 1.6 10.6 43.1 0.6 21.6 0.0 12.5 3.4 21.4 34.1 9.1 0.6 18.2 34.1 8.8 32.0 17.6 0.0 11.0 9.3 6.8 8.8 27.3 14.5 1.0 6.6 6.6 20.1 29.2 KLC4 "bA387M24.3, KNSL8" ENSG00000137171 "Kinesin light chain 4" Q9NSK0 6 43040777-43075095 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 89.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 81.9;Hepatocytes: 67.8;Paneth cells: 70.4;Proximal enterocytes: 143.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 65.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030168, HPA030169" Enhanced Approved Mitochondria,Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Mitochondria Cytosol "HPA030168: AB_10599285, HPA030169: AB_10601105" "unprognostic (2.96e-2)" "unprognostic (6.29e-2)" "unprognostic (1.83e-2)" "unprognostic (1.08e-2)" "unprognostic (3.67e-2)" "unprognostic (5.63e-3)" "unprognostic (6.36e-3)" "unprognostic (1.19e-2)" "unprognostic (4.67e-2)" "unprognostic (1.30e-1)" "unprognostic (1.47e-2)" "unprognostic (9.22e-2)" "prognostic favorable (6.99e-6)" "unprognostic (2.08e-1)" "unprognostic (3.93e-1)" "unprognostic (1.59e-1)" "unprognostic (1.06e-2)" 12.3 17.2 18.8 11.2 19.6 12.4 13.4 21.8 22.8 16.6 18.6 41.1 72.5 15.1 23.0 10.9 17.7 17.9 25.1 18.7 19.0 24.2 89.9 16.5 13.5 21.2 19.2 19.7 17.8 28.7 24.1 12.2 21.2 17.0 34.2 23.8 19.9 15.8 22.9 17.5 63.7 14.0 17.5 12.5 31.8 24.8 19.6 17.1 19.7 22.8 11.1 17.3 12.9 20.9 7.5 6.0 15.9 18.9 15.0 14.7 13.7 5.5 8.5 9.5 15.6 9.8 11.5 9.9 19.7 13.4 12.6 12.3 15.8 14.9 7.2 10.0 19.1 11.4 18.2 44.0 14.5 5.4 9.1 19.3 18.2 11.8 10.8 29.8 12.1 20.5 7.9 12.8 8.0 13.0 16.2 12.2 6.1 65.4 7.9 12.6 9.0 19.3 14.3 6.5 26.7 12.8 10.3 9.6 20.3 14.9 16.4 15.0 10.2 10.6 12.8 5.4 5.9 25.8 9.9 24.1 5.8 8.5 3.9 2.6 2.6 3.2 2.6 2.6 3.4 3.7 3.7 2.5 3.0 3.2 4.5 3.3 6.5 4.9 2.6 8.7 4.5 2.3 18.8 19.6 21.8 22.8 18.7 19.0 21.2 19.2 21.2 17.5 19.6 20.9 4.1 16.0 14.4 23.5 4.3 3.7 9.2 12.5 15.9 21.8 8.0 8.8 10.6 20.0 10.8 14.7 29.2 11.8 11.4 81.9 19.6 8.7 13.4 8.9 3.8 5.8 22.3 9.3 17.2 9.8 4.9 5.9 33.6 7.9 7.0 12.2 7.5 67.8 6.5 11.8 24.2 35.3 10.2 5.7 2.9 6.5 10.2 3.6 3.6 6.5 5.3 16.3 4.1 10.6 9.7 7.6 70.4 6.8 7.4 5.0 143.4 23.5 19.0 28.0 13.1 6.0 5.5 27.3 15.6 9.4 4.5 13.5 5.3 6.2 44.0 6.6 KLF12 "AP-2rep, AP2REP, HSPC122" ENSG00000118922 "Kruppel like factor 12" Q9Y4X4 13 73686089-73995056 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 9 "Astrocytes: 319.3;Excitatory neurons: 211.9;Inhibitory neurons: 562.2;Microglial cells: 208.9;Oligodendrocyte precursor cells: 760.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064146, HPA075652" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "HPA064146: AB_2685198, HPA075652: " "unprognostic (1.49e-1)" "unprognostic (7.65e-2)" "unprognostic (7.79e-2)" "prognostic unfavorable (5.03e-6)" "unprognostic (1.35e-1)" "unprognostic (3.01e-1)" "unprognostic (9.22e-2)" "unprognostic (8.59e-2)" "unprognostic (5.19e-2)" "unprognostic (3.70e-2)" "unprognostic (2.60e-2)" "unprognostic (3.47e-2)" "unprognostic (1.01e-3)" "unprognostic (1.07e-1)" "unprognostic (2.18e-1)" "unprognostic (1.02e-1)" "unprognostic (6.67e-3)" 2.9 1.9 4.1 6.1 2.9 3.0 2.9 5.5 5.3 2.3 2.7 3.7 1.5 3.6 11.2 2.0 2.8 3.0 5.3 5.6 4.5 5.5 9.9 2.6 11.3 3.3 4.9 5.2 0.9 0.8 3.4 0.8 3.6 2.5 2.9 8.9 1.4 3.2 3.6 1.6 3.6 3.4 3.1 7.6 2.7 1.6 5.1 10.3 1.6 8.5 9.8 2.6 2.0 3.5 0.0 1.4 13.6 0.0 7.5 16.3 0.1 5.4 2.7 5.9 6.2 1.1 3.4 10.5 2.5 8.1 2.3 3.7 3.6 4.2 15.7 6.9 4.9 0.4 6.3 0.0 2.4 7.0 2.5 14.3 1.1 8.4 6.7 11.4 11.9 8.0 0.0 2.6 18.0 1.1 13.6 0.0 1.9 0.5 2.7 7.4 4.9 0.1 3.3 0.2 3.2 13.8 3.8 1.7 6.3 5.0 0.4 1.1 0.1 11.4 3.5 5.2 2.6 7.0 9.6 3.3 20.2 0.0 5.9 0.6 0.0 0.0 2.0 0.2 2.4 0.8 1.7 2.3 0.2 0.7 1.2 1.9 0.0 1.4 0.3 0.4 0.9 0.8 4.1 2.9 5.5 5.3 5.6 4.5 3.3 4.9 3.6 3.1 5.1 3.5 6.6 6.4 1.8 319.3 30.5 4.2 1.3 4.3 0.6 20.8 5.4 6.2 18.7 5.7 3.7 3.7 37.5 0.1 35.4 3.0 3.9 2.1 0.8 4.6 18.8 8.4 0.0 7.8 211.9 0.0 0.1 12.3 2.0 6.3 0.0 29.2 5.0 20.3 0.1 8.4 562.2 1.5 10.2 8.0 12.1 1.6 20.8 5.0 3.6 208.9 6.4 11.2 43.3 760.0 25.4 0.4 3.2 28.6 21.9 3.3 0.2 7.0 6.0 13.1 0.0 12.2 18.1 0.5 3.5 0.7 6.7 0.1 40.3 4.9 3.9 1.8 KLLN killin ENSG00000227268 "Killin, p53 regulated DNA replication inhibitor" B2CW77 10 87859158-87863533 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 4.5" "Cell type enhanced" "Detected in many" "granulocytes: 5.7;Sertoli cells: 6.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "JURKAT: 5.0;Karpas-707: 5.1" HPA074502 Supported Nucleoplasm,Nucleoli No No "Cluster 42: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Nucleoli "HPA074502: AB_2686695" "unprognostic (4.53e-2)" "unprognostic (1.19e-1)" "unprognostic (1.82e-1)" "unprognostic (1.68e-2)" "unprognostic (3.71e-1)" "unprognostic (6.53e-2)" "unprognostic (1.37e-1)" "unprognostic (3.59e-1)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (3.12e-3)" "unprognostic (1.57e-2)" "unprognostic (4.79e-4)" "unprognostic (1.38e-2)" "unprognostic (1.00e-1)" "unprognostic (9.02e-4)" "unprognostic (1.60e-1)" 1.0 0.7 1.0 0.6 0.7 0.5 0.6 1.5 1.6 0.7 0.6 0.9 0.4 0.5 1.0 0.4 1.4 0.4 0.5 0.7 0.9 0.9 0.9 0.4 0.8 0.5 0.6 0.4 0.2 0.5 0.5 0.6 0.6 0.4 0.8 1.0 0.3 0.5 4.5 0.4 0.4 0.5 0.3 0.8 0.6 1.0 0.6 1.0 0.7 0.5 0.8 0.3 0.3 1.5 0.8 1.0 1.1 0.7 0.5 0.3 0.8 0.7 0.9 0.5 0.7 0.6 2.6 2.0 0.3 0.2 0.5 0.9 0.7 0.8 0.4 0.5 0.3 0.7 1.5 0.6 0.6 1.4 0.5 0.6 0.8 0.7 0.8 0.9 0.3 5.0 0.4 5.1 0.5 1.8 4.1 1.6 0.4 0.6 0.5 2.6 0.1 2.6 0.4 0.8 0.4 1.0 0.9 0.6 0.1 0.7 1.6 1.2 0.3 0.5 0.3 0.9 0.3 2.9 3.3 2.9 0.9 2.9 0.6 1.6 0.3 0.6 0.2 0.5 0.4 0.4 0.3 0.3 0.3 0.5 0.4 0.3 2.5 0.6 0.8 0.5 0.2 0.2 1.0 0.7 1.5 1.6 0.7 0.9 0.5 0.6 0.6 0.3 0.6 1.5 0.6 0.0 0.0 0.3 0.5 0.1 0.3 0.2 0.6 1.7 1.0 1.3 2.7 1.5 1.3 0.0 0.0 0.7 2.0 3.0 0.0 0.2 3.9 0.8 0.9 0.6 0.0 0.8 0.4 0.2 0.4 1.1 3.6 0.4 5.7 0.3 0.7 0.4 0.3 3.3 0.5 1.8 0.0 1.3 0.0 2.0 0.0 0.6 0.0 0.0 0.3 1.6 0.0 0.0 0.1 0.3 2.5 0.0 0.2 0.3 1.8 1.9 2.3 1.0 6.6 1.1 2.9 0.3 1.2 0.6 0.4 0.5 0.7 0.3 1.3 0.2 KNL1 "AF15Q14, CASC5, CT29, D40, hKNL-1, hSpc105, KIAA1570, MCPH4, PPP1R55, Spc7" ENSG00000137812 "Kinetochore scaffold 1" Q8NG31 15 40594020-40664342 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 5.3;lymphoid tissue: 7.4;testis: 16.9" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 8.5;Extravillous trophoblasts: 11.3;Granulosa cells: 22.8;Hofbauer cells: 7.1;Proximal tubular cells: 11.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "HPA026624, HPA049647" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" Yes Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA026624: AB_10601696, HPA049647: AB_2680840" "unprognostic (5.35e-2)" "unprognostic (1.01e-1)" "unprognostic (5.59e-3)" "unprognostic (4.22e-2)" "unprognostic (1.59e-2)" "unprognostic (5.66e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (2.06e-2)" "unprognostic (1.43e-1)" "unprognostic (3.20e-4)" "unprognostic (2.22e-2)" "unprognostic (1.93e-12)" "unprognostic (3.07e-2)" "unprognostic (3.08e-1)" "unprognostic (8.45e-2)" "unprognostic (7.36e-2)" 0.2 0.1 0.1 1.9 0.0 5.3 0.3 0.2 0.2 0.2 0.2 1.3 1.6 0.3 0.2 1.0 0.1 0.3 0.1 0.1 0.1 0.5 0.7 0.4 3.6 0.1 0.3 0.0 0.0 0.3 0.0 1.3 0.1 0.1 1.4 0.2 0.2 0.0 0.0 0.8 1.7 0.7 0.0 0.6 0.9 16.9 0.3 7.4 0.3 0.1 3.4 0.5 0.2 0.1 19.1 9.3 18.0 13.8 0.5 2.6 8.6 20.5 8.1 16.0 13.1 11.6 7.2 11.9 6.1 9.3 12.0 21.9 17.6 9.7 16.3 21.4 5.0 35.5 15.5 3.9 0.0 26.2 17.8 0.5 0.4 10.8 6.4 2.1 13.8 20.9 22.9 19.2 18.3 6.1 23.5 6.1 9.4 11.3 9.5 21.2 25.8 5.9 2.6 15.6 15.9 7.7 17.7 10.6 2.1 5.9 11.1 9.0 13.1 18.7 16.3 21.9 11.7 7.5 27.9 22.3 7.6 18.5 18.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.3 0.5 0.0 0.1 0.1 0.1 0.1 0.0 0.6 0.0 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.3 0.1 0.0 0.3 0.1 0.3 0.0 0.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.1 1.1 0.0 0.0 1.8 1.8 0.0 8.5 2.6 0.0 1.9 0.2 0.0 3.5 3.5 1.9 0.0 0.0 0.0 0.6 11.3 4.2 0.0 2.9 0.0 22.8 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.1 0.0 0.0 11.5 0.7 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 3.7 1.9 1.7 0.0 0.0 KRT19 "CK19, K19, K1CS, MGC15366" ENSG00000171345 "Keratin 19" P08727 17 41523617-41528308 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 889.0;salivary gland: 810.7;urinary bladder: 781.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 7444.0;Club cells: 5055.9;Ductal cells: 4717.9;Extravillous trophoblasts: 6919.3;Pancreatic endocrine cells: 7374.9;Proximal enterocytes: 8623.3;Urothelial cells: 5959.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 1945.3;HBEC3-KT: 2945.0;MCF7: 2220.9;RT4: 3146.7;SK-BR-3: 5446.1;T-47d: 3674.2" "Not detected" "Not detected" "CAB000031, HPA002465" Enhanced Supported "Intermediate filaments" NA NA 300000000 "Cluster 40: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Intermediate filaments" "CAB000031: AB_2234418, HPA002465: AB_1079179" "unprognostic (1.09e-1)" "unprognostic (1.83e-1)" "unprognostic (3.86e-2)" "unprognostic (1.59e-2)" "unprognostic (2.24e-2)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" "unprognostic (2.80e-2)" "unprognostic (3.14e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.82e-5)" "unprognostic (1.90e-2)" "prognostic unfavorable (2.98e-5)" "unprognostic (3.52e-2)" "unprognostic (2.14e-1)" "unprognostic (3.08e-2)" "unprognostic (2.35e-2)" 89.3 18.7 2.0 61.7 2.4 0.3 403.3 7.9 2.5 250.0 1.6 525.7 348.3 57.9 72.0 889.0 176.1 298.6 13.5 1.5 1.7 141.8 7.7 204.1 0.4 1.6 2.9 74.4 48.8 14.3 15.6 175.1 2.2 208.3 359.2 0.1 810.7 194.2 1.3 141.9 776.1 46.5 1.4 1.2 631.5 3.4 1.8 127.8 28.3 1.6 98.3 781.4 317.0 1.8 2.6 343.4 0.0 6.3 0.7 1.8 1169.3 412.1 0.5 12.8 2.9 992.6 1945.3 0.4 393.3 199.0 1.5 1044.6 0.1 2945.0 2.5 0.8 10.4 0.2 213.4 692.3 30.3 0.0 82.0 0.7 524.9 9.0 0.4 0.2 26.2 0.0 148.4 2.5 0.1 2220.9 5.9 3.0 18.5 1323.5 492.7 2.9 0.1 5.8 1335.4 3146.7 40.0 1.7 3.3 5446.1 0.1 266.5 3674.2 0.3 1.7 3.6 6.1 7.7 0.7 1.1 0.8 2.0 1.5 0.3 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.0 2.4 7.9 2.5 1.5 1.7 1.6 2.9 2.2 1.4 1.8 1.8 10.5 673.1 185.5 0.0 17.8 5.2 4317.3 7444.0 1715.8 0.0 1393.0 867.5 2.9 662.0 5055.9 892.0 0.0 1160.8 20.5 3599.6 1.9 4717.9 0.1 737.2 102.8 41.9 362.5 0.0 0.1 2589.9 6919.3 171.8 1571.4 1010.7 94.6 1.0 1.1 0.7 179.0 0.0 0.1 1382.4 2720.0 2.6 2.5 2.6 37.9 25.5 190.3 1.0 30.0 0.8 0.0 0.0 0.0 7374.9 3399.6 88.8 19.9 2228.8 8623.3 26.7 1954.3 0.0 0.0 0.0 240.0 1.1 1.6 1302.6 1.1 2127.5 36.1 4.8 1619.0 5959.8 KRT80 KB20 ENSG00000167767 "Keratin 80" Q6KB66 12 52168996-52192014 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 219.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 25.9;Ductal cells: 63.0;Endometrial ciliated cells: 33.0;Glandular and luminal cells: 33.5;Pancreatic endocrine cells: 48.4;Suprabasal keratinocytes: 37.4;Syncytiotrophoblasts: 58.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 202.5;MCF7: 287.3;SK-BR-3: 127.7;U-2 OS: 174.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA077836, HPA077918" Enhanced "Intermediate filaments" No No 230000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "Intermediate filaments" "HPA077836: AB_2686857, HPA077918: AB_2686871" "prognostic unfavorable (1.05e-4)" "unprognostic (5.45e-3)" "unprognostic (5.35e-2)" "unprognostic (9.19e-3)" "unprognostic (2.85e-4)" "unprognostic (6.68e-2)" "unprognostic (2.06e-3)" "unprognostic (1.26e-3)" "unprognostic (5.60e-2)" "unprognostic (4.06e-2)" "unprognostic (7.06e-3)" "unprognostic (1.02e-1)" "unprognostic (8.79e-3)" "unprognostic (8.85e-2)" "unprognostic (2.03e-1)" "unprognostic (1.51e-1)" "unprognostic (2.98e-2)" 0.4 5.3 0.0 0.3 0.0 0.1 8.7 0.3 0.6 18.5 0.0 0.1 0.5 1.2 0.9 51.0 3.4 2.7 0.3 0.1 0.0 2.7 0.7 3.4 0.0 0.0 0.0 0.2 11.6 7.0 0.4 7.3 0.0 1.5 0.1 0.5 24.8 3.4 1.3 219.1 0.3 0.1 0.0 0.1 0.5 0.3 0.0 0.8 0.8 0.0 41.1 9.9 36.5 0.0 202.5 66.7 0.0 0.0 0.0 0.0 54.2 2.9 1.8 15.3 4.6 4.5 85.9 0.0 94.4 2.3 99.4 98.5 0.0 1.3 5.3 0.4 0.0 0.0 99.4 2.4 10.1 0.1 0.1 1.1 11.9 3.5 23.0 70.2 23.2 0.0 0.0 0.1 5.4 287.3 0.2 0.1 0.4 58.5 10.1 0.2 79.4 3.0 87.1 35.7 24.5 1.3 50.1 127.7 1.2 5.6 24.1 1.0 13.5 0.3 174.4 0.2 71.6 0.1 0.3 0.5 18.0 7.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 6.2 3.9 4.4 0.0 0.0 14.7 4.6 0.4 10.0 9.4 11.0 0.0 25.9 0.1 0.3 0.0 63.0 0.9 33.0 3.7 0.5 0.0 0.0 0.1 20.4 3.4 0.4 0.0 33.5 0.0 0.6 0.0 0.0 2.0 0.0 0.0 0.1 12.2 0.0 1.6 0.5 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 48.4 0.0 0.0 0.0 4.8 0.1 1.8 21.7 0.0 0.0 0.4 2.2 0.1 0.0 2.9 37.4 58.3 0.3 0.3 0.3 8.5 L2HGDH "C14orf160, FLJ12618" ENSG00000087299 "L-2-hydroxyglutarate dehydrogenase" Q9H9P8 14 50237563-50312229 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 56.3;Excitatory neurons: 60.5;Inhibitory neurons: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065409, HPA069708" Approved Enhanced Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 36: HEL - Hemostasis" "Cluster 9: Photoreceptor cells - Phototransduction" Mitochondria "HPA065409: AB_2685485, HPA069708: AB_2686179" "unprognostic (1.74e-1)" "unprognostic (1.15e-2)" "unprognostic (1.13e-2)" "unprognostic (1.23e-3)" "unprognostic (1.04e-2)" "unprognostic (4.33e-2)" "unprognostic (8.84e-2)" "unprognostic (1.58e-2)" "unprognostic (4.17e-2)" "unprognostic (9.91e-2)" "unprognostic (2.84e-1)" "unprognostic (1.97e-1)" "prognostic favorable (9.75e-10)" "unprognostic (1.24e-2)" "unprognostic (5.88e-2)" "unprognostic (1.45e-1)" "unprognostic (1.02e-2)" 4.6 2.5 2.9 2.2 2.9 2.7 3.7 6.1 5.5 2.3 1.3 4.3 4.7 2.4 3.0 5.1 3.1 2.0 5.2 2.7 2.5 19.6 12.6 1.8 2.6 1.2 2.4 2.5 3.9 6.1 2.3 1.7 1.1 3.3 5.0 11.4 2.8 3.2 15.5 5.1 3.6 2.5 1.2 1.3 4.3 3.9 2.4 3.0 4.8 14.7 3.4 2.4 2.3 4.1 24.3 16.6 6.8 6.6 3.3 2.2 19.1 7.9 4.4 12.2 14.3 26.8 10.8 19.0 9.0 3.2 9.7 17.4 20.6 8.2 13.5 15.2 11.9 41.1 10.9 3.7 3.1 14.7 13.7 2.0 5.2 8.1 7.0 3.1 5.3 19.3 14.7 11.6 3.2 29.0 16.7 6.7 9.9 20.6 17.6 15.6 22.0 14.8 11.4 28.0 13.8 9.9 23.3 17.5 10.4 9.0 22.9 4.0 5.0 7.7 21.5 9.0 10.6 10.5 25.6 26.3 4.3 7.3 8.8 8.6 0.4 0.9 0.9 0.1 2.2 0.8 1.1 1.0 0.6 0.6 1.3 1.7 0.5 1.7 0.1 1.0 1.6 0.5 2.9 2.9 6.1 5.5 2.7 2.5 1.2 2.4 1.1 1.2 2.4 4.1 1.9 41.7 19.2 16.6 5.1 3.7 2.7 2.1 8.6 15.5 3.9 2.2 14.7 2.8 20.4 12.9 56.3 6.4 6.1 4.8 15.6 3.8 35.1 5.2 2.8 4.6 7.8 7.4 60.5 4.2 6.6 5.3 7.7 5.6 18.9 6.0 2.9 14.2 2.1 11.8 61.4 4.3 0.0 2.7 0.6 8.8 2.5 3.3 1.8 13.1 2.4 6.1 7.2 20.6 18.9 2.5 3.6 4.5 3.3 2.7 6.0 21.7 18.4 40.3 0.0 5.8 3.9 14.3 12.6 10.5 6.3 4.9 5.0 4.6 7.6 2.1 LCK ENSG00000182866 "LCK proto-oncogene, Src family tyrosine kinase" P06239 1 32251239-32286165 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "lymphoid tissue: 343.0" "Group enriched" "Detected in many" 9 "dendritic cells: 143.9;NK-cells: 272.9;T-cells: 255.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in all" 12 "gdT-cell: 1109.8;MAIT T-cell: 1034.8;memory CD4 T-cell: 1123.8;memory CD8 T-cell: 1201.7;naive CD4 T-cell: 1260.7;naive CD8 T-cell: 1168.7;NK-cell: 641.5;T-reg: 1682.7" "Group enriched" "Detected in all" 12 "NK-cells: 641.5;T-cells: 1682.7" "Group enriched" "Detected in some" 6 "JURKAT: 365.7;MOLT-4: 536.9;U-698: 302.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "HPA003494, CAB003816" Enhanced Approved "Golgi apparatus" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus" "CAB003816: AB_562158, HPA003494: AB_1852751" "unprognostic (6.38e-3)" "unprognostic (5.45e-3)" "unprognostic (8.39e-2)" "prognostic favorable (2.96e-6)" "unprognostic (2.20e-2)" "prognostic favorable (2.91e-4)" "unprognostic (4.78e-3)" "unprognostic (1.33e-2)" "prognostic favorable (5.65e-5)" "unprognostic (3.07e-2)" "unprognostic (3.80e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.60e-5)" "unprognostic (8.15e-2)" "unprognostic (4.05e-2)" "unprognostic (7.39e-2)" "unprognostic (1.17e-2)" 3.4 2.2 0.4 50.6 0.5 13.7 2.3 0.4 0.5 2.2 0.7 6.9 7.6 1.7 13.0 3.9 2.1 9.4 1.9 0.5 0.4 3.8 3.8 11.4 111.0 0.8 0.5 1.6 0.9 0.5 0.8 1.1 0.6 2.8 6.5 0.0 4.8 1.4 1.3 1.9 23.1 2.3 0.6 39.9 12.1 1.1 0.5 343.0 3.7 1.4 79.6 13.2 2.7 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.7 64.1 3.5 0.0 0.3 0.1 0.0 0.2 0.0 0.1 0.6 0.0 0.0 1.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 365.7 0.2 0.0 0.0 0.0 536.9 0.2 5.9 4.6 0.3 20.6 0.1 0.3 0.3 0.2 0.1 0.0 0.1 0.3 0.3 0.4 0.6 0.4 0.0 0.0 1.7 0.1 0.1 0.7 0.3 302.7 0.0 0.1 0.0 12.8 5.2 6.0 1109.8 4.9 1034.8 62.0 1123.8 1201.7 5.2 98.9 1260.7 1168.7 33.6 641.5 6.0 7.7 1682.7 1836.9 0.4 0.5 0.4 0.5 0.5 0.4 0.8 0.5 0.6 0.6 0.5 0.6 4.9 0.0 9.3 0.0 23.4 4.6 1.2 0.4 0.0 0.0 3.5 5.2 1.8 4.3 1.6 3.7 0.0 0.3 143.9 0.9 0.0 0.6 0.1 1.0 0.5 3.4 2.4 10.1 0.2 0.5 0.2 3.1 7.7 0.7 5.1 0.0 4.6 1.5 0.3 0.0 0.2 0.3 0.0 7.8 7.3 0.0 0.0 8.1 3.6 0.0 8.7 0.0 272.9 0.5 0.1 4.7 0.0 0.4 15.7 1.0 0.0 1.4 1.8 0.0 0.0 1.5 2.4 4.5 2.0 0.5 3.1 0.4 255.5 2.9 1.3 1.1 LECT2 "chm-II, chm2" ENSG00000145826 "Leukocyte cell derived chemotaxin 2" O14960 5 135922279-135954983 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "liver: 477.9" "Group enriched" "Detected in some" 15 "Early spermatids: 147.7;Hepatocytes: 100.7;Late spermatids: 55.8" "Cancer enriched" "Detected in single" 216 "liver cancer: 35.1" "Region enhanced" "Detected in some" "cerebellum: 6.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA043883, HPA058246" Enhanced Supported Vesicles,Cytosol "Secreted to blood" NA NA 26500000 5300000 "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 20: HeLa - Mitochondria" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol Vesicles "HPA043883: AB_2678714, HPA058246: " "prognostic favorable (4.16e-5)" "unprognostic (2.57e-2)" "unprognostic (3.52e-1)" 0.2 0.5 0.4 0.4 0.8 2.4 0.4 6.3 2.8 0.1 0.0 0.2 0.5 0.3 0.8 0.4 0.1 0.4 0.1 0.9 0.0 0.6 477.9 0.3 0.9 0.0 0.0 0.3 0.1 0.2 0.0 0.2 0.1 0.4 0.2 3.1 0.7 0.2 2.1 1.4 0.9 0.1 0.0 0.9 0.3 8.8 0.0 0.2 0.4 0.0 0.2 0.1 0.0 1.1 0.3 0.4 0.5 0.7 0.2 0.4 0.6 0.1 0.0 0.0 0.0 0.1 0.4 0.8 0.6 0.3 0.3 0.5 0.0 0.2 0.0 0.3 1.0 0.7 0.7 1.3 0.3 1.0 0.1 0.2 0.1 0.3 0.3 0.6 0.1 0.8 0.2 0.3 0.6 0.0 0.4 0.4 0.5 0.3 0.6 0.5 0.5 0.2 0.2 0.9 0.3 0.6 0.0 0.2 0.0 0.9 0.1 0.5 0.8 0.3 0.4 0.4 0.1 1.1 0.5 0.3 0.3 0.9 0.8 0.6 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.4 0.8 6.3 2.8 0.9 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 147.7 0.0 0.1 0.3 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 100.7 0.0 0.0 0.1 0.0 0.0 2.9 0.0 55.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 6.6 0.0 0.0 1.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.1 LHX2 "hLhx2, LH-2" ENSG00000106689 "LIM homeobox 2" P50458 9 124001670-124033301 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 99.8;choroid plexus: 48.5;retina: 34.1" "Cell type enhanced" "Detected in some" "Astrocytes: 68.6;Early spermatids: 43.1;Muller glia cells: 254.6" "Group enriched" "Detected in many" 5 "cervical cancer: 3.2;glioma: 10.7;melanoma: 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 23.2;GAMG: 17.9;HAP1: 23.5;HeLa: 15.5;NTERA-2: 28.5;U-138 MG: 14.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA000838 Supported Approved Nucleoplasm NA NA "Cluster 65: Brain - Ion transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA000838: AB_2666109" "unprognostic (3.60e-3)" "prognostic favorable (9.52e-4)" "unprognostic (3.52e-1)" "unprognostic (9.97e-2)" "unprognostic (1.29e-1)" "unprognostic (1.12e-2)" "unprognostic (6.37e-3)" "unprognostic (1.07e-1)" "unprognostic (4.59e-2)" "unprognostic (3.24e-1)" "unprognostic (2.96e-1)" "unprognostic (1.32e-2)" "unprognostic (4.66e-15)" "unprognostic (1.72e-1)" "unprognostic (2.92e-1)" "unprognostic (2.46e-2)" "unprognostic (1.77e-1)" 0.1 0.1 77.8 0.2 78.1 0.0 0.2 48.5 99.8 0.0 48.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 88.1 51.2 0.3 6.7 0.0 0.3 49.5 52.7 0.2 0.0 0.0 9.8 3.4 50.2 0.0 0.1 34.1 0.1 0.0 0.0 6.1 0.2 0.0 48.3 0.1 0.0 3.0 54.9 0.1 0.0 0.0 0.2 0.1 0.0 73.9 0.0 7.2 0.2 23.2 0.0 0.3 2.6 0.7 0.3 1.8 0.2 7.8 0.0 0.2 3.0 1.4 17.9 0.2 23.5 0.0 0.9 0.0 5.0 0.0 15.5 0.4 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 12.1 0.0 0.2 28.5 0.0 7.0 6.5 0.1 0.0 0.0 0.1 9.2 0.1 5.7 0.0 0.0 0.2 8.0 3.1 0.0 14.6 0.6 4.2 1.1 0.4 5.0 0.0 0.8 3.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 77.8 78.1 48.5 99.8 88.1 51.2 49.5 52.7 50.2 48.3 54.9 73.9 0.1 0.0 0.0 68.6 0.2 0.0 0.0 0.0 0.0 3.2 0.1 0.3 0.6 0.0 0.0 0.0 2.1 0.1 0.0 0.1 0.0 0.0 43.1 0.1 0.0 0.3 0.0 0.0 20.6 0.0 8.9 0.1 0.0 0.0 0.0 0.1 3.9 0.0 4.0 8.4 2.5 0.0 0.0 0.0 0.3 21.7 0.0 0.1 0.0 1.9 0.0 254.6 0.0 5.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.4 0.2 4.2 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 LILRA5 "CD85, CD85f, ILT11, LILRB7, LIR9" ENSG00000187116 "Leukocyte immunoglobulin like receptor A5" A6NI73 19 54307070-54313166 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.5;lymphoid tissue: 76.3" "Group enriched" "Detected in some" 5 "Kupffer cells: 64.1;Macrophages: 136.1;monocytes: 53.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "classical monocyte: 128.6;intermediate monocyte: 252.7;neutrophil: 137.2;non-classical monocyte: 311.7" "Group enriched" "Detected in many" 6 "granulocytes: 137.2;monocytes: 311.7" "Cell line enriched" "Detected in single" 31 "RPMI-8226: 4.1" "Secreted to blood" NA NA 670000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (8.52e-2)" "unprognostic (3.61e-1)" "unprognostic (2.23e-1)" "unprognostic (1.77e-1)" "unprognostic (1.57e-2)" "unprognostic (6.56e-2)" "unprognostic (2.90e-1)" "unprognostic (1.86e-1)" "unprognostic (3.11e-1)" "unprognostic (6.61e-3)" "unprognostic (2.01e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (7.78e-4)" "unprognostic (3.61e-2)" "unprognostic (6.51e-3)" "unprognostic (4.68e-2)" "unprognostic (6.21e-2)" 7.9 1.3 0.2 36.9 0.2 43.5 1.9 0.2 0.9 0.7 0.6 1.8 0.0 1.0 0.0 0.9 4.1 1.7 2.5 0.3 0.2 1.8 3.8 22.2 0.5 0.6 0.3 0.6 0.9 0.0 0.9 1.6 0.5 1.4 1.2 0.0 1.2 0.0 0.7 0.3 2.8 6.9 0.3 76.3 2.1 0.3 0.4 0.4 1.0 0.0 0.4 15.7 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 128.6 0.5 0.0 252.7 0.3 0.0 0.0 0.0 39.2 0.1 0.0 0.0 137.2 0.3 311.7 20.3 0.1 65.0 0.2 0.2 0.2 0.9 0.3 0.2 0.6 0.3 0.5 0.3 0.4 0.4 0.1 0.0 8.5 0.0 1.3 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.5 0.0 3.1 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.4 0.1 0.0 0.1 1.0 0.0 0.0 11.4 0.0 0.4 0.7 6.5 0.0 0.1 0.0 0.0 64.1 14.3 0.0 0.0 136.1 0.0 0.0 53.4 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.4 2.2 0.0 0.0 0.8 0.2 0.1 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.1 LIME1 "dJ583P15.4, FLJ20406, LIME" ENSG00000203896 "Lck interacting transmembrane adaptor 1" Q9H400 20 63736283-63739103 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 242.8" "Cell type enriched" "Detected in some" 5 "Plasma cells: 210.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 314.8;MAIT T-cell: 285.2;memory CD4 T-cell: 437.6;memory CD8 T-cell: 412.5;naive CD4 T-cell: 289.4;naive CD8 T-cell: 319.4;plasmacytoid DC: 749.3;T-reg: 689.4" "Group enriched" "Detected in all" 8 "dendritic cells: 749.3;T-cells: 689.4" "Cell line enhanced" "Detected in many" "Karpas-707: 33.9;MOLT-4: 37.9;RPMI-8226: 144.4;U-266/70: 71.1" "Low region specificity" "Detected in many" CAB015363 Approved "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 58: T-cells - T-cell receptor" "CAB015363: AB_629890" "unprognostic (1.16e-1)" "unprognostic (2.35e-1)" "unprognostic (5.95e-3)" "unprognostic (3.01e-1)" "unprognostic (1.34e-1)" "unprognostic (3.85e-3)" "unprognostic (3.06e-2)" "unprognostic (1.46e-1)" "unprognostic (1.36e-1)" "unprognostic (1.94e-1)" "unprognostic (1.05e-3)" "unprognostic (1.51e-3)" "prognostic unfavorable (5.04e-5)" "unprognostic (2.39e-2)" "unprognostic (4.25e-2)" "unprognostic (1.67e-1)" "prognostic favorable (6.92e-6)" 8.9 5.6 2.2 5.6 5.6 4.7 5.8 2.6 7.0 8.8 0.8 11.8 2.2 5.9 0.0 11.2 6.8 0.0 5.1 2.9 1.4 54.5 242.8 9.0 10.7 2.8 1.8 9.6 5.1 0.1 11.3 0.1 2.5 13.4 0.3 0.0 12.5 0.4 3.9 13.2 18.7 0.0 1.0 43.2 18.3 5.9 3.5 6.1 11.2 0.0 1.2 7.6 9.2 4.8 2.0 0.6 0.1 0.4 0.0 0.0 4.9 2.6 0.2 0.3 0.0 1.1 2.1 5.7 3.8 0.1 0.0 5.1 0.0 0.3 0.3 2.5 4.8 1.1 2.3 25.4 0.0 1.5 2.1 0.2 0.7 0.0 0.0 0.0 0.0 16.4 2.1 33.9 0.0 1.1 37.9 10.7 2.0 1.3 6.6 25.9 0.8 144.4 0.4 0.3 2.0 2.9 1.3 1.3 2.8 0.0 1.1 0.8 0.5 1.8 2.8 1.9 1.5 71.1 3.0 12.7 1.5 1.1 0.7 1.9 1.5 1.8 314.8 1.0 285.2 76.4 437.6 412.5 2.4 37.2 289.4 319.4 10.6 85.5 1.7 749.3 689.4 193.8 2.2 5.6 2.6 7.0 2.9 1.4 2.8 1.8 2.5 1.0 3.5 4.8 0.0 0.0 0.0 21.5 7.2 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.8 7.7 0.0 0.0 0.3 22.4 0.0 0.0 0.0 0.4 3.1 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 5.6 0.1 0.0 0.0 9.0 9.6 0.0 0.0 0.0 210.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 5.8 0.1 0.0 36.7 0.0 0.1 0.0 LMO7 "FBX20, FBXO20, KIAA0858" ENSG00000136153 "LIM domain 7" Q8WWI1 13 75620434-75859870 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 248.8" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 1682.7;Urothelial cells: 435.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 177 "amygdala: 12.6;basal ganglia: 19.9;cerebral cortex: 25.6;hippocampal formation: 14.9;white matter: 15.4" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 13.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 343.4;fHDF/TERT166: 568.2;LHCN-M2: 525.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "amygdala: 20.8;basal ganglia: 32.8;cerebral cortex: 26.6;hippocampal formation: 33.8" "HPA020923, HPA050184" Enhanced Supported "Actin filaments,Cytosol" NA NA 8200 "Cluster 32: T-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" Cytosol "HPA020923: AB_1852963, HPA050184: AB_2681045" "unprognostic (2.07e-1)" "unprognostic (1.97e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (5.12e-4)" "unprognostic (1.75e-2)" "unprognostic (1.44e-1)" "unprognostic (1.57e-2)" "unprognostic (1.97e-1)" "unprognostic (1.52e-2)" "unprognostic (3.42e-2)" "prognostic unfavorable (3.51e-4)" "unprognostic (2.14e-1)" "prognostic favorable (7.75e-12)" "unprognostic (2.49e-1)" "unprognostic (2.82e-1)" "unprognostic (1.08e-1)" "unprognostic (8.33e-2)" 4.4 5.3 12.6 10.6 19.9 4.1 9.3 0.0 25.6 12.8 4.8 47.4 66.3 5.7 12.1 153.7 14.5 43.3 248.8 14.9 0.0 44.1 61.9 178.7 11.0 0.0 0.0 18.6 25.5 11.8 6.4 41.3 0.0 27.3 32.5 4.8 32.4 15.1 143.5 21.1 79.7 7.9 0.0 5.0 62.7 18.2 0.0 56.8 53.5 99.5 37.1 24.5 38.4 15.4 77.8 43.6 1.7 1.3 86.5 61.4 14.9 343.4 168.3 85.4 91.6 107.4 97.8 6.6 25.7 568.2 21.2 73.5 18.9 16.6 97.8 105.4 4.5 47.8 229.2 102.2 25.0 15.3 24.0 42.0 31.1 37.0 42.3 207.9 36.2 14.7 1.7 0.5 525.9 30.4 11.6 6.4 2.2 119.6 65.0 7.2 159.5 1.6 36.0 18.1 5.4 11.6 62.2 10.8 13.8 8.6 14.0 11.3 55.6 208.7 38.7 25.4 84.9 22.6 18.4 27.8 61.6 17.0 97.0 4.5 0.2 2.7 0.6 0.5 0.9 1.1 3.2 1.0 0.4 2.3 13.6 8.6 0.1 0.6 0.4 1.1 1.4 2.6 12.6 19.9 0.0 25.6 14.9 0.0 0.0 0.0 0.0 0.0 0.0 15.4 1.5 1682.7 279.7 22.2 4.3 24.0 74.7 59.9 72.8 6.8 10.5 13.2 362.6 51.5 317.2 62.5 2.1 45.5 3.6 378.5 15.6 81.5 6.2 92.0 19.0 9.0 71.2 3.6 162.3 37.8 8.7 38.0 276.3 244.4 20.3 9.5 6.1 72.7 6.0 6.7 82.5 96.6 67.1 3.5 4.4 8.0 42.0 6.4 16.0 39.4 2.8 1.9 3.1 30.7 48.4 228.8 351.2 42.5 2.1 344.9 213.8 15.5 199.5 10.5 13.1 27.2 18.1 11.2 6.3 100.9 45.3 17.0 12.9 2.5 75.2 435.7 LPA "LP, Lp(a)" ENSG00000198670 Lipoprotein(a) P08519 6 160531482-160664275 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid transport, Transport" "Hydrolase, Protease, Serine protease" Atherosclerosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "liver: 76.7" "Cell type enriched" "Detected in some" 28 "Hepatocytes: 80.7" "Cancer enriched" "Detected in single" 38 "liver cancer: 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "RT4: 1.0" "CAB016072, HPA060604" Supported "Secreted to blood" NA NA 78800000000 1800000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 15: Hepatocytes - Hemostasis" "CAB016072: AB_2135240, HPA060604: AB_2684330" "unprognostic (2.16e-1)" "unprognostic (5.10e-1)" "unprognostic (7.75e-3)" "unprognostic (6.70e-2)" "unprognostic (1.60e-1)" "unprognostic (4.17e-3)" "unprognostic (1.59e-1)" "unprognostic (6.38e-3)" "unprognostic (3.63e-2)" "unprognostic (3.18e-1)" "unprognostic (7.45e-3)" "unprognostic (2.56e-1)" "unprognostic (1.80e-1)" "unprognostic (1.34e-1)" "unprognostic (3.72e-2)" 0.0 0.1 2.0 0.0 1.2 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.2 0.4 0.1 0.8 0.0 0.0 0.8 6.3 0.5 76.7 0.1 0.0 1.8 1.9 0.2 0.6 0.0 0.0 0.0 1.3 0.6 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 4.2 1.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.2 0.0 1.1 0.8 6.3 1.8 1.9 1.3 0.2 4.2 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 2.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.1 0.0 0.2 0.0 2.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 80.7 0.0 0.0 1.3 0.0 0.0 2.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 LRRC3 "C21orf102, C21orf30, DKFZP434C128, LRRC3DN" ENSG00000160233 "Leucine rich repeat containing 3" Q9BY71 21 44455510-44462196 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 15.5" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 30.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 8.7;U-2 OS: 6.3" "Low region specificity" "Detected in all" HPA017975 Uncertain NA NA "Cluster 6: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 2: Hepatocytes - Metabolism" "HPA017975: AB_1853307" "unprognostic (1.36e-2)" "unprognostic (5.48e-3)" "unprognostic (1.49e-2)" "unprognostic (2.10e-4)" "unprognostic (1.55e-1)" "unprognostic (1.74e-2)" "unprognostic (7.20e-3)" "unprognostic (2.59e-1)" "unprognostic (4.61e-1)" "unprognostic (7.43e-2)" "unprognostic (1.37e-1)" "unprognostic (1.38e-2)" "unprognostic (1.74e-5)" "unprognostic (6.44e-2)" "unprognostic (2.01e-1)" "unprognostic (7.51e-2)" "unprognostic (6.66e-3)" 1.9 1.4 0.8 0.7 0.5 0.6 1.5 0.2 0.7 1.4 0.3 6.6 1.7 1.3 0.4 1.1 1.5 2.2 1.9 0.6 2.0 0.7 15.5 1.6 0.5 0.6 0.9 3.4 0.7 0.3 1.3 0.9 0.6 0.8 0.8 0.3 1.0 0.6 0.4 1.8 1.6 1.5 0.2 1.1 3.8 1.7 1.2 0.5 0.6 1.0 0.3 2.0 1.3 0.6 0.5 0.4 3.5 2.9 0.0 0.0 8.7 1.5 0.0 0.1 0.0 1.3 1.2 0.0 2.6 0.7 1.9 0.1 1.7 0.0 0.0 0.2 3.8 0.0 0.4 4.0 0.6 0.0 2.3 1.1 1.4 0.0 0.0 0.0 1.4 0.6 0.3 4.5 0.0 1.3 0.5 0.2 0.9 4.5 1.4 1.9 0.0 1.5 0.1 0.1 2.8 3.2 1.3 0.3 0.6 1.9 0.8 1.9 2.8 0.0 6.3 0.0 0.0 2.5 5.2 0.0 0.0 1.6 0.5 0.3 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.8 0.5 0.2 0.7 0.6 2.0 0.6 0.9 0.6 0.2 1.2 0.6 2.6 0.0 1.5 0.0 0.8 0.6 1.1 0.0 3.4 1.1 0.6 0.9 2.0 1.5 0.0 1.8 0.0 0.2 0.3 1.6 0.0 0.3 0.3 0.2 0.4 0.6 4.2 2.7 0.0 0.4 6.6 2.5 1.5 0.9 1.3 2.4 1.1 30.7 2.5 0.0 0.1 1.8 0.0 2.5 0.5 1.5 0.6 1.1 0.0 0.0 3.2 1.4 1.0 0.0 0.1 1.7 0.3 0.7 0.2 1.3 1.8 0.0 0.0 0.0 0.0 0.8 1.4 0.9 2.0 0.6 0.6 0.3 0.8 0.3 1.7 0.7 LRRC4B "DKFZp761A179, HSM, LRIG4" ENSG00000131409 "Leucine rich repeat containing 4B" Q9NT99 19 50516892-50568435 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 61.2;cervix: 41.3;pituitary gland: 31.9" "Cell type enhanced" "Detected in some" "Astrocytes: 34.9;Bipolar cells: 19.6;Excitatory neurons: 32.1;Inhibitory neurons: 38.5;Oligodendrocyte precursor cells: 29.7;Oligodendrocytes: 48.9" "Group enriched" "Detected in many" 9 "glioma: 36.5;testis cancer: 9.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 8.7;HMC-1: 32.1;REH: 8.7;SH-SY5Y: 27.5;U-2 OS: 25.3;WM-115: 10.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058986 Uncertain NA NA 2700000 "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA058986: AB_2683871" "unprognostic (1.52e-2)" "unprognostic (1.14e-1)" "unprognostic (4.46e-2)" "unprognostic (4.48e-2)" "unprognostic (3.56e-1)" "unprognostic (5.39e-4)" "unprognostic (2.70e-2)" "unprognostic (1.11e-1)" "unprognostic (5.28e-2)" "unprognostic (4.61e-3)" "unprognostic (1.11e-3)" "unprognostic (3.41e-1)" "unprognostic (3.15e-5)" "unprognostic (4.29e-2)" "unprognostic (2.61e-1)" "unprognostic (3.64e-1)" "unprognostic (2.17e-1)" 2.8 5.3 54.4 0.9 35.6 0.0 2.1 20.7 61.2 41.3 0.0 2.8 0.8 16.2 0.1 1.9 10.0 1.2 1.8 49.3 33.2 1.8 1.3 5.8 1.3 50.9 47.6 5.1 0.8 0.2 31.9 4.2 33.3 3.3 0.1 1.6 0.8 1.0 0.7 1.2 3.3 1.3 19.9 0.8 2.9 2.4 38.2 0.0 2.6 0.1 0.5 5.8 13.0 38.1 0.0 0.5 2.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 4.9 0.0 0.7 0.1 0.1 0.0 0.0 0.3 8.7 0.0 0.0 0.0 0.0 0.1 32.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.1 0.5 0.0 1.0 0.1 0.0 8.2 0.0 0.0 8.7 0.0 0.1 0.0 0.0 0.0 27.5 0.0 0.0 5.7 0.2 0.0 0.3 0.0 0.0 25.3 0.0 0.0 0.6 0.1 0.1 0.1 0.3 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.4 35.6 20.7 61.2 49.3 33.2 50.9 47.6 33.3 19.9 38.2 38.1 0.7 0.0 0.0 34.9 0.0 0.0 0.0 0.0 0.0 19.6 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 2.5 0.9 0.0 0.0 32.1 0.0 0.0 1.3 0.0 0.1 0.0 0.2 0.7 0.0 0.1 10.1 38.5 0.0 0.0 0.0 0.3 2.2 2.8 0.0 0.0 2.8 0.0 1.6 0.0 29.7 48.9 0.0 0.0 4.5 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.1 5.8 4.8 8.1 0.2 0.0 0.1 0.1 0.1 0.0 0.0 LRRTM4 FLJ12568 ENSG00000176204 "Leucine rich repeat transmembrane neuronal 4" Q86VH4 2 76747685-77593319 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 17.6;retina: 6.8" "Group enriched" "Detected in some" 16 "Excitatory neurons: 3972.6;Inhibitory neurons: 2310.6;Oligodendrocyte precursor cells: 3758.4" "Cancer enhanced" "Detected in some" "glioma: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 10 "Karpas-707: 125.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 10: Brain - Neuronal signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (2.00e-1)" "unprognostic (4.40e-2)" "unprognostic (3.13e-1)" "unprognostic (4.72e-4)" "unprognostic (7.20e-2)" "unprognostic (1.30e-1)" "unprognostic (1.27e-2)" "unprognostic (9.15e-2)" "unprognostic (3.93e-1)" "unprognostic (5.84e-2)" "unprognostic (4.22e-2)" "unprognostic (1.40e-1)" "unprognostic (2.64e-1)" "unprognostic (5.77e-3)" "unprognostic (3.54e-2)" "unprognostic (7.99e-2)" 0.4 0.6 5.8 0.3 11.4 1.7 0.2 0.1 17.6 0.4 0.0 0.5 0.8 0.4 1.5 0.8 0.2 0.7 0.1 13.5 1.6 0.2 1.3 0.8 0.4 0.2 4.1 0.6 0.5 0.0 1.0 0.9 1.2 0.6 0.5 6.8 0.9 1.5 1.6 0.8 0.5 0.3 0.0 0.5 0.6 0.3 0.0 0.1 0.7 0.3 0.2 0.3 0.5 14.5 1.4 1.7 0.9 0.8 0.0 0.0 0.9 0.3 0.0 0.0 0.0 2.1 0.5 1.0 2.2 0.8 0.7 0.8 0.2 0.0 0.3 0.8 2.5 0.5 4.8 3.1 0.4 1.3 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.5 125.8 0.0 2.8 0.5 0.7 12.2 0.2 1.2 0.5 0.1 2.6 0.0 4.1 3.7 1.4 0.8 0.7 0.8 2.0 1.4 0.9 0.0 2.9 3.7 0.1 0.2 0.0 2.4 0.1 2.8 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.5 0.2 0.1 0.0 0.1 0.0 5.8 11.4 0.1 17.6 13.5 1.6 0.2 4.1 1.2 0.0 0.0 14.5 0.0 0.0 0.5 208.6 0.0 0.0 0.0 0.0 0.0 21.2 0.0 0.3 0.3 0.0 0.0 0.0 4.2 0.1 0.0 0.0 0.0 0.0 1.1 0.4 0.2 0.4 0.0 0.0 3972.6 0.0 0.0 2.7 0.0 0.1 0.0 0.0 0.7 0.5 0.0 0.0 2310.6 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 84.3 0.0 2.8 0.0 3758.4 176.0 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.7 2.3 6.6 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 LST1 "B144, D6S49E, LST-1" ENSG00000204482 "Leukocyte specific transcript 1" O00453 6 31586124-31588909 "Predicted intracellular proteins, Predicted membrane proteins" "Cell shape, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 100.3;lung: 48.8;lymphoid tissue: 181.9" "Group enriched" "Detected in many" 11 "Hofbauer cells: 407.1;Kupffer cells: 1326.9;Langerhans cells: 1240.5;Macrophages: 871.6;monocytes: 1096.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 1746.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 39.3;HMC-1: 73.6;MOLT-4: 39.6;NB-4: 76.2;THP-1: 179.9;U-937: 92.9" "Low region specificity" "Detected in all" HPA079451 Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA079451: " "unprognostic (1.08e-2)" "prognostic favorable (7.89e-4)" "unprognostic (6.99e-2)" "unprognostic (4.16e-3)" "unprognostic (3.13e-1)" "unprognostic (3.92e-2)" "unprognostic (3.65e-1)" "unprognostic (7.06e-3)" "unprognostic (2.81e-3)" "unprognostic (2.12e-1)" "unprognostic (1.70e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (5.97e-5)" "unprognostic (1.47e-1)" "prognostic unfavorable (7.62e-4)" "unprognostic (1.03e-1)" "unprognostic (1.95e-1)" 15.2 10.2 4.3 22.0 4.3 100.3 7.9 4.6 7.2 5.6 5.0 7.9 7.1 3.7 1.4 5.5 6.6 3.1 7.6 4.6 5.5 10.8 14.4 48.8 13.8 6.1 4.9 3.0 4.7 0.9 6.1 4.7 6.6 8.9 3.0 0.5 6.9 2.3 2.1 7.8 15.0 5.1 5.4 181.9 5.7 1.8 5.2 15.1 4.6 1.9 7.1 9.1 5.1 6.0 0.3 0.6 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.2 2.5 0.6 0.0 0.0 0.5 0.3 0.4 0.3 12.9 0.0 39.3 0.0 0.0 0.7 29.3 73.6 0.0 0.3 0.1 1.2 0.3 0.9 0.8 0.1 0.2 0.0 0.0 39.6 76.2 0.1 0.0 0.0 18.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 179.9 0.3 0.0 0.4 0.0 0.2 0.1 0.0 5.9 0.0 92.9 0.0 112.2 419.7 681.6 9.4 1273.9 80.7 32.8 15.9 20.2 392.9 21.9 10.9 9.0 1133.0 21.6 1746.7 69.9 12.0 541.6 4.3 4.3 4.6 7.2 4.6 5.5 6.1 4.9 6.6 5.4 5.2 6.0 5.4 35.3 86.7 0.7 43.7 35.2 0.3 0.2 0.0 0.3 3.2 12.2 1.9 7.2 13.0 11.0 0.0 2.9 42.8 1.0 0.0 0.6 1.5 0.4 1.9 12.9 0.0 15.1 0.2 0.2 3.8 9.2 1.5 0.4 70.3 0.1 22.9 5.8 407.1 0.0 0.3 0.0 2.0 1326.9 1240.5 5.4 3.7 871.6 44.4 24.4 1096.6 0.7 60.8 0.5 0.1 0.1 1.1 1.2 4.7 1.0 0.0 3.8 11.0 0.2 26.3 2.2 2.8 2.4 4.6 0.4 28.3 5.3 43.6 0.0 0.4 0.3 LTBP1 ENSG00000049323 "Latent transforming growth factor beta binding protein 1" Q14766 2 32946953-33399509 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 161.4" "Cell type enhanced" "Detected in many" "Astrocytes: 108.4;Fibroblasts: 116.1;Leydig cells: 90.4;Peritubular cells: 161.0;Skeletal myocytes: 85.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "basophil: 3.1" "Lineage enriched" "Detected in single" 14 "granulocytes: 3.1" "Cell line enhanced" "Detected in many" "ASC TERT1: 569.4;HSkMC: 185.3;HUVEC TERT2: 194.5;U-2197: 181.1;U-87 MG: 255.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB025428 Approved "Secreted to extracellular matrix" NA NA 96000000 "Cluster 10: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB025428: " "unprognostic (1.02e-2)" "unprognostic (1.12e-1)" "unprognostic (5.29e-2)" "unprognostic (6.23e-2)" "unprognostic (3.11e-3)" "unprognostic (1.83e-1)" "unprognostic (1.06e-3)" "unprognostic (5.67e-2)" "unprognostic (7.48e-2)" "unprognostic (1.14e-1)" "unprognostic (9.96e-3)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.79e-6)" "unprognostic (4.61e-2)" "unprognostic (1.06e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.62e-4)" 22.9 13.1 7.8 22.1 9.4 11.5 14.5 7.1 7.5 161.4 10.5 27.2 10.2 58.9 37.8 21.2 37.0 73.0 89.0 8.8 9.1 38.6 18.6 27.5 6.9 12.1 10.6 30.2 7.9 2.4 9.0 73.2 9.2 46.9 16.5 0.7 14.6 73.6 15.7 10.8 15.0 96.7 9.1 8.3 32.8 17.9 8.8 8.2 6.5 28.4 18.7 53.9 28.3 13.4 0.3 12.5 31.3 0.3 26.1 569.4 13.5 46.5 95.7 6.4 9.3 25.3 4.6 41.3 1.0 6.0 8.8 2.4 0.7 1.5 22.0 0.6 15.3 135.6 15.0 4.1 118.6 0.5 15.7 185.3 4.4 141.2 6.9 61.8 194.5 6.3 8.7 0.3 51.1 19.9 5.5 0.2 22.4 1.0 39.2 4.7 65.8 0.6 0.4 22.4 6.3 3.4 9.5 72.1 0.8 49.1 27.9 0.4 126.4 6.4 26.2 181.1 37.6 74.8 80.0 58.8 255.9 5.2 10.8 3.1 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 5.3 7.8 9.4 7.1 7.5 8.8 9.1 12.1 10.6 9.2 9.1 8.8 13.4 33.6 0.0 0.6 108.4 0.4 13.5 5.6 13.0 10.2 0.0 6.9 6.6 80.9 4.3 3.6 1.8 0.0 45.2 0.3 12.9 0.0 9.6 6.3 7.3 18.3 28.1 1.2 30.3 30.4 6.5 23.4 116.1 10.2 10.5 0.0 11.8 20.3 11.0 7.6 0.0 54.3 2.8 2.0 0.3 18.1 7.1 90.4 12.0 19.6 39.4 0.4 0.2 0.0 70.4 52.4 19.1 3.3 161.0 1.3 19.1 0.7 0.3 6.3 0.3 59.2 85.8 67.9 0.7 11.9 6.9 9.8 43.5 2.0 2.6 4.1 33.4 LTBP4 "FLJ46318, FLJ90018, LTBP-4, LTBP-4L" ENSG00000090006 "Latent transforming growth factor beta binding protein 4" Q8N2S1 19 40592883-40629818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 327.1;Leydig cells: 972.3;Peritubular cells: 624.4;Skeletal myocytes: 229.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 120.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015194 Approved "Secreted to extracellular matrix" NA NA 9700000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "CAB015194: AB_2139064" "unprognostic (3.29e-2)" "unprognostic (3.91e-1)" "unprognostic (6.09e-2)" "unprognostic (9.94e-2)" "unprognostic (7.86e-3)" "unprognostic (8.41e-3)" "unprognostic (2.67e-2)" "unprognostic (5.94e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (2.36e-4)" "unprognostic (3.34e-2)" "unprognostic (4.62e-2)" "unprognostic (5.52e-3)" "unprognostic (5.40e-2)" "unprognostic (1.01e-1)" "unprognostic (1.79e-1)" "unprognostic (6.83e-2)" 138.5 48.5 11.3 22.3 10.9 8.3 98.8 1.7 13.3 334.6 9.6 144.5 59.2 309.6 44.7 100.6 246.8 39.3 401.9 10.7 14.2 64.7 37.4 242.5 24.8 16.2 10.3 315.2 37.2 22.6 75.9 38.3 16.4 253.6 38.2 3.7 82.8 126.3 63.0 73.0 135.4 74.4 11.3 80.5 125.3 78.5 14.2 12.9 173.2 156.7 14.0 188.6 374.5 15.3 19.8 21.3 41.7 56.5 15.1 16.0 6.6 7.7 24.9 7.8 6.4 6.4 43.8 22.4 34.9 13.1 12.4 26.3 10.6 26.8 2.6 61.0 3.3 7.3 53.7 2.4 49.4 3.0 23.1 19.9 21.7 15.6 27.8 41.0 4.9 21.6 46.7 120.3 1.9 19.7 3.1 1.3 4.9 56.1 24.9 51.9 1.1 35.6 3.9 1.7 1.8 17.4 28.3 21.5 7.4 6.4 11.9 11.3 20.4 1.3 81.4 2.6 16.7 26.8 24.9 7.1 35.1 28.5 20.4 0.0 1.5 0.4 8.1 2.4 5.5 3.5 7.7 6.5 2.7 2.0 3.2 3.4 0.3 3.0 1.3 5.0 5.5 2.3 11.3 10.9 1.7 13.3 10.7 14.2 16.2 10.3 16.4 11.3 14.2 15.3 84.7 6.4 14.1 2.0 11.6 57.6 30.9 62.8 56.3 60.4 13.0 18.2 15.5 17.2 18.5 22.0 0.0 1.5 12.7 38.2 1.9 6.3 11.1 14.8 154.7 29.9 4.2 12.4 8.1 4.7 2.6 327.1 37.2 24.2 10.2 13.5 102.4 3.3 7.5 40.4 11.3 42.2 6.1 6.4 39.6 39.0 972.3 13.9 58.7 15.0 9.5 3.5 16.5 2.0 14.0 6.9 16.6 624.4 16.5 23.6 97.7 0.3 7.1 3.2 59.2 229.2 52.8 50.7 36.3 38.2 29.1 2.6 24.9 10.2 36.4 27.2 LUM "LDC, SLRR2D" ENSG00000139329 Lumican P51884 12 91102629-91111494 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 739.0;placenta: 535.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 966.4;Fibroblasts: 2136.1;Leydig cells: 401.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 4 "cerebral cortex: 5.6" "Immune cell enriched" "Detected in single" 122 "basophil: 12.1" "Lineage enriched" "Detected in single" 122 "granulocytes: 12.1" "Cell line enriched" "Detected in some" 5 "BJ hTERT+: 1991.0" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 9 "spinal cord: 149.2" "HPA001522, CAB025783" Supported "Secreted to extracellular matrix" NA NA 29000000000 "Cluster 38: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB025783: , HPA001522: AB_1079285" "unprognostic (5.54e-2)" "unprognostic (2.27e-1)" "unprognostic (3.32e-1)" "unprognostic (2.75e-1)" "unprognostic (1.65e-1)" "unprognostic (8.38e-2)" "unprognostic (1.09e-1)" "unprognostic (2.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.19e-1)" "unprognostic (1.65e-2)" "unprognostic (2.20e-2)" "prognostic unfavorable (1.75e-6)" "unprognostic (5.25e-3)" "unprognostic (2.27e-2)" "unprognostic (2.38e-2)" "unprognostic (2.06e-2)" 161.5 133.5 0.6 68.1 0.7 0.3 153.2 0.6 5.6 199.8 4.2 85.0 56.1 301.0 88.3 75.7 59.2 739.0 183.8 0.7 0.9 85.0 34.6 211.4 41.3 0.9 0.8 92.9 72.9 26.3 5.3 535.9 0.8 115.2 133.0 5.7 14.3 67.4 9.6 20.0 90.6 354.5 0.7 4.8 47.1 17.5 1.3 13.4 30.8 73.0 80.3 486.0 39.2 0.8 0.0 0.3 6.9 0.0 237.4 115.9 0.7 400.8 1991.0 16.0 24.3 0.0 0.1 0.0 0.0 339.9 0.0 0.6 0.0 0.0 5.4 0.0 0.0 0.0 21.5 0.0 183.7 0.6 0.1 160.5 0.0 33.7 1.0 0.9 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.6 1.2 0.0 0.9 0.0 0.2 0.1 0.0 0.0 0.3 14.9 0.1 0.0 10.8 16.3 0.0 0.0 0.0 17.0 4.5 14.3 0.0 0.2 0.0 0.0 8.8 0.1 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.6 5.6 0.7 0.9 0.9 0.8 0.8 0.7 1.3 0.8 77.5 12.8 30.9 0.0 0.6 97.6 1.2 0.8 3.4 0.2 9.4 8.6 15.2 0.0 5.0 0.0 2.1 44.9 4.0 0.1 0.0 0.7 3.5 27.0 966.4 27.2 0.0 0.0 0.0 0.0 38.9 2136.1 8.6 15.2 18.3 0.0 55.0 0.3 63.6 0.0 0.2 0.3 0.0 0.3 143.5 8.7 401.7 9.5 117.4 16.9 1.0 86.9 0.0 0.0 0.0 2.1 0.0 44.8 6.3 4.9 0.4 0.3 0.8 3.0 0.0 39.1 165.5 0.2 0.9 5.9 100.2 84.0 14.5 27.4 0.0 4.1 LYRM9 "C17orf108, HSD24" ENSG00000232859 "LYR motif containing 9" A8MSI8 17 27878314-27894752 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 78.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 23.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023051 Uncertain NA NA "Cluster 32: T-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 39: Non-specific - Basic cellular processes" "HPA023051: AB_10602333" "unprognostic (1.31e-1)" "unprognostic (6.20e-3)" "unprognostic (2.38e-1)" "unprognostic (6.16e-3)" "unprognostic (2.05e-1)" "unprognostic (3.88e-2)" "unprognostic (1.14e-3)" "unprognostic (1.18e-3)" "unprognostic (1.03e-1)" "unprognostic (2.01e-2)" "prognostic favorable (9.46e-4)" "unprognostic (1.75e-1)" "prognostic favorable (5.41e-4)" "unprognostic (4.24e-2)" "unprognostic (1.30e-1)" "unprognostic (1.31e-1)" "unprognostic (7.93e-3)" 19.4 43.9 32.2 5.5 33.4 6.4 18.2 18.9 34.4 17.0 22.8 15.6 7.8 17.4 32.9 6.3 19.0 10.5 16.5 35.8 31.9 32.5 15.6 10.2 12.2 25.8 24.8 26.8 22.8 24.5 27.9 4.7 24.9 16.5 6.0 7.4 14.3 18.9 20.8 15.6 11.2 9.3 23.2 15.6 13.7 18.2 37.5 7.2 34.4 10.9 8.5 12.2 11.1 26.6 1.1 1.3 4.8 5.1 9.5 9.7 6.9 2.2 3.7 1.1 0.6 10.5 2.0 0.6 7.4 2.4 0.7 0.3 0.5 2.4 0.6 7.3 3.4 3.2 0.2 0.6 14.1 0.2 1.6 14.3 4.8 0.5 4.4 4.2 2.5 11.4 1.0 1.2 5.4 6.1 2.2 0.4 2.5 4.6 0.1 2.1 0.2 0.0 8.2 2.3 3.4 3.0 5.8 8.6 11.1 2.6 23.1 1.5 2.8 2.0 1.3 5.9 1.1 3.1 0.6 0.1 2.2 0.8 2.3 5.1 3.0 2.3 5.9 5.6 6.0 7.6 8.1 6.1 3.9 11.2 14.8 10.1 8.0 4.3 7.5 2.5 9.5 6.0 32.2 33.4 18.9 34.4 35.8 31.9 25.8 24.8 24.9 23.2 37.5 26.6 15.4 9.6 9.7 10.7 13.7 6.5 7.4 11.4 5.7 17.8 19.0 23.5 13.3 20.0 5.4 53.3 14.6 18.7 5.3 1.4 78.2 13.6 3.9 10.5 5.4 12.2 9.0 6.1 19.5 23.4 6.7 14.7 6.1 5.6 11.4 14.9 13.2 14.1 10.0 16.8 18.8 6.1 12.2 8.0 12.3 2.2 18.6 7.0 39.2 2.8 15.4 31.5 16.5 9.5 14.5 8.4 3.1 23.3 2.0 5.2 11.9 40.9 16.3 14.5 26.3 11.4 11.8 35.4 39.5 3.4 6.5 4.5 13.2 25.5 8.9 5.3 MACC1 "7A5, SH3BP4L" ENSG00000183742 "MET transcriptional regulator MACC1" Q6ZN28 7 20134655-20217404 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Growth factor, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 11.7" "Cell type enhanced" "Detected in many" "Club cells: 102.4;Glandular and luminal cells: 100.5;Pancreatic endocrine cells: 136.4;Respiratory ciliated cells: 93.4;Urothelial cells: 238.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 98.0;CAPAN-2: 22.2;HaCaT: 66.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA020081, HPA020103, HPA029476, CAB068194" Supported Approved Mitochondria NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "CAB068194: AB_2665682, HPA020081: AB_1844386, HPA020103: AB_1844387, HPA029476: AB_10610136" "unprognostic (1.59e-2)" "unprognostic (1.88e-1)" "unprognostic (3.43e-2)" "prognostic unfavorable (1.56e-5)" "unprognostic (2.26e-1)" "unprognostic (1.42e-2)" "unprognostic (7.01e-2)" "unprognostic (2.52e-2)" "unprognostic (2.05e-1)" "unprognostic (2.43e-2)" "unprognostic (2.43e-3)" "unprognostic (1.03e-1)" "prognostic favorable (5.71e-9)" "unprognostic (4.49e-2)" "unprognostic (2.91e-1)" "unprognostic (1.78e-1)" "unprognostic (6.93e-3)" 0.6 2.3 1.4 1.3 0.6 1.0 4.3 1.0 1.4 2.9 0.0 2.7 9.8 0.8 0.7 8.8 0.9 2.9 0.2 1.0 0.3 6.6 0.4 5.4 0.9 1.1 0.7 0.1 3.3 0.4 0.3 0.2 1.4 1.0 3.2 0.6 5.6 2.6 0.1 2.9 11.7 0.3 0.2 0.8 4.9 0.5 0.9 0.6 1.1 0.0 3.5 3.9 3.0 1.3 98.0 0.4 0.4 0.0 0.1 0.2 0.9 0.1 0.0 0.0 0.0 21.6 22.2 13.8 1.0 0.0 0.1 66.9 0.2 0.9 0.0 0.1 0.4 13.0 0.3 0.0 0.0 5.5 0.4 0.0 0.7 0.0 0.1 0.2 0.1 0.3 14.2 6.5 0.1 8.1 0.0 1.4 1.0 19.1 0.1 0.0 0.6 10.5 16.5 6.7 0.3 0.5 0.0 7.5 0.1 0.4 3.9 0.2 0.4 0.2 0.2 0.1 0.2 20.1 1.0 5.0 0.1 0.7 0.2 0.2 0.1 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.2 0.1 0.0 0.1 1.4 0.6 1.0 1.4 1.0 0.3 1.1 0.7 1.4 0.2 0.9 1.3 4.1 70.5 57.4 0.7 6.5 2.8 75.8 11.3 2.8 3.3 22.2 7.5 0.6 24.3 102.4 40.5 2.1 0.8 2.2 16.9 7.9 51.4 2.9 59.6 16.3 4.1 38.7 4.2 1.0 63.8 0.2 5.7 18.3 100.5 12.6 0.4 2.2 0.8 4.4 1.7 2.9 19.5 34.6 0.9 3.8 1.2 2.1 11.0 1.8 0.0 8.4 0.3 1.0 0.0 0.9 136.4 20.4 2.6 6.3 72.8 40.2 17.5 93.4 1.3 0.0 0.8 3.6 0.4 0.6 13.2 4.0 0.3 2.9 0.3 17.5 238.8 MACROD1 LRP16 ENSG00000133315 "Mono-ADP ribosylhydrolase 1" Q9BQ69 11 63998558-64166113 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 290.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 137.0;Proximal tubular cells: 333.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 73.8;RPMI-8226: 145.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041031, HPA071075" Uncertain Supported Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 59: Non-specific - Translation" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA041031: AB_10794435, HPA071075: AB_2686341" "unprognostic (1.19e-2)" "unprognostic (2.15e-1)" "unprognostic (1.38e-1)" "unprognostic (3.14e-2)" "unprognostic (3.88e-2)" "unprognostic (6.03e-2)" "unprognostic (1.95e-2)" "unprognostic (2.82e-1)" "unprognostic (2.44e-2)" "unprognostic (1.34e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.15e-1)" "prognostic favorable (4.68e-6)" "unprognostic (2.45e-2)" "unprognostic (9.92e-2)" "unprognostic (2.36e-1)" "unprognostic (2.86e-2)" 14.9 14.1 6.4 1.3 5.9 2.8 17.3 6.8 12.7 15.6 5.9 21.3 5.7 13.8 0.9 18.6 15.3 2.2 111.6 6.4 8.2 55.1 50.2 10.4 1.1 8.6 7.9 21.6 49.5 4.1 11.8 1.6 8.8 19.6 1.4 1.2 30.1 5.5 290.1 26.0 10.7 1.1 6.6 6.5 27.2 4.7 9.1 1.0 32.0 58.9 0.5 17.4 16.8 7.4 12.7 5.7 1.9 10.2 1.7 1.0 10.9 7.5 3.2 5.3 5.1 5.3 33.2 44.9 25.4 0.6 2.6 29.8 1.9 0.1 0.6 3.6 21.9 16.8 23.3 29.7 6.1 13.8 1.8 2.5 3.4 0.6 1.7 4.5 1.8 14.7 15.2 8.5 1.1 73.8 20.1 45.1 5.5 4.3 24.4 18.7 11.5 145.4 1.8 0.7 15.7 31.2 5.7 40.3 41.4 0.2 29.8 1.0 2.9 4.9 7.4 7.0 0.8 17.8 3.1 7.4 3.4 13.4 4.6 0.0 0.0 0.0 0.4 0.2 0.4 0.1 0.4 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 6.4 5.9 6.8 12.7 6.4 8.2 8.6 7.9 8.8 6.6 9.1 7.4 19.4 0.0 4.6 6.8 7.1 28.0 39.8 7.5 57.5 15.1 46.2 45.0 32.5 30.0 8.6 42.3 0.0 35.6 1.3 34.6 137.0 20.8 7.1 19.0 13.3 11.9 22.9 8.0 7.1 40.4 16.1 15.9 20.9 22.7 0.0 41.6 9.7 45.3 11.7 11.8 12.4 55.2 8.2 6.9 5.1 26.8 24.8 7.2 39.2 4.7 2.4 16.9 1.0 13.6 6.9 19.2 35.2 14.3 12.9 37.6 23.0 333.4 3.1 20.6 19.7 55.7 19.1 8.2 32.5 46.3 37.1 23.9 6.1 18.8 67.9 49.8 MAGI1 "AIP3, BAIAP1, BAP1, MAGI-1, TNRC19, WWP3" ENSG00000151276 "Membrane associated guanylate kinase, WW and PDZ domain containing 1" Q96QZ7 3 65353525-66038834 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 497.7;Inhibitory neurons: 809.8;Oligodendrocyte precursor cells: 368.4;Oligodendrocytes: 532.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 36.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031851, HPA031853, HPA077002" Supported Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 18: Non-specific - Mitochondria" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Cell Junctions" Nucleoplasm "HPA031851: AB_10599289, HPA031853: AB_10602095, HPA077002: " "unprognostic (5.00e-2)" "unprognostic (9.84e-2)" "unprognostic (6.00e-3)" "unprognostic (1.73e-3)" "unprognostic (1.64e-1)" "unprognostic (2.17e-2)" "unprognostic (1.46e-3)" "unprognostic (9.46e-3)" "unprognostic (8.59e-2)" "unprognostic (2.19e-1)" "unprognostic (6.58e-2)" "unprognostic (2.05e-3)" "prognostic favorable (4.55e-8)" "unprognostic (3.51e-2)" "unprognostic (1.34e-1)" "unprognostic (1.68e-2)" "unprognostic (8.03e-2)" 11.3 5.0 3.7 1.3 4.8 0.0 12.5 6.3 5.9 5.5 3.9 9.7 5.0 6.2 2.0 8.0 5.8 5.3 9.0 4.7 5.3 10.2 13.4 8.8 1.1 3.7 3.8 2.7 12.6 5.9 7.7 5.3 2.6 7.1 4.2 7.0 11.6 4.9 3.8 12.5 6.4 3.1 2.7 11.9 14.7 10.3 4.1 2.0 13.4 4.1 1.8 5.4 7.2 4.9 4.1 2.2 12.3 1.3 2.4 1.7 5.5 7.0 5.9 2.6 4.0 15.1 3.5 0.0 1.0 8.3 2.1 1.2 3.4 2.4 4.1 0.0 1.9 36.1 4.3 10.2 1.5 0.0 1.1 2.7 2.0 8.9 1.8 6.8 6.0 4.7 15.6 0.0 2.8 3.1 0.0 0.0 16.6 12.2 2.1 0.0 3.5 0.9 3.1 13.5 3.9 10.8 2.7 3.3 0.1 8.0 6.4 0.0 1.6 8.2 6.0 2.1 2.9 0.0 0.0 0.0 4.8 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 4.8 6.3 5.9 4.7 5.3 3.7 3.8 2.6 2.7 4.1 4.9 102.8 76.9 29.8 204.7 1.3 22.3 17.7 7.9 26.2 98.3 46.5 37.5 35.6 102.9 22.5 23.9 75.0 20.2 0.5 51.0 3.9 44.3 179.1 35.8 35.5 55.5 36.5 2.7 497.7 31.8 2.4 9.6 47.4 50.8 1.3 78.4 82.5 60.9 4.8 232.2 809.8 40.3 12.2 5.0 3.6 27.0 6.5 1.8 5.4 170.5 0.6 15.2 0.0 368.4 532.1 40.3 25.4 8.6 0.2 14.7 33.2 12.2 40.3 26.4 32.9 7.0 17.5 44.7 12.3 12.7 18.8 5.1 2.7 27.1 26.3 11.9 MAN1A1 ENSG00000111885 "Mannosidase alpha class 1A member 1" P33908 6 119177205-119349761 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 154.6" "Cell type enhanced" "Detected in many" "Early spermatids: 232.5;Excitatory neurons: 165.0;Hepatocytes: 270.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 273.1;Hep G2: 204.0;Karpas-707: 219.6;U-266/70: 294.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037058, HPA053198, HPA063561" Uncertain Supported "Golgi apparatus" NA NA 460000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" "CAB037058: AB_477183, HPA053198: AB_2682078, HPA063561: AB_2685042" "unprognostic (1.50e-1)" "unprognostic (7.36e-3)" "unprognostic (4.83e-2)" "unprognostic (2.21e-2)" "unprognostic (2.95e-2)" "unprognostic (2.19e-1)" "unprognostic (3.33e-3)" "unprognostic (3.44e-2)" "unprognostic (2.04e-1)" "unprognostic (5.11e-2)" "unprognostic (1.68e-3)" "unprognostic (4.62e-1)" "unprognostic (2.37e-2)" "unprognostic (3.49e-2)" "unprognostic (2.25e-1)" "unprognostic (6.89e-2)" "unprognostic (3.40e-1)" 102.2 48.5 4.2 32.8 12.3 28.9 34.3 1.2 8.9 25.9 5.1 36.1 52.7 23.8 8.8 22.7 16.0 47.1 15.3 8.0 4.6 66.6 154.6 35.8 34.8 2.9 5.0 20.1 32.7 25.8 4.6 79.4 2.5 18.1 29.3 6.2 42.7 15.0 7.6 14.3 69.8 27.2 3.3 36.5 25.9 7.0 8.4 18.9 22.6 31.0 25.9 56.0 17.1 5.9 0.2 0.0 3.4 0.0 273.1 119.9 6.6 6.9 41.4 5.1 12.5 19.8 2.6 43.2 0.3 26.5 65.7 0.4 7.6 0.1 6.4 64.5 19.4 36.3 3.9 204.0 27.2 0.1 17.7 82.4 5.3 41.6 25.3 22.1 3.4 12.6 128.1 219.6 39.7 6.1 1.7 0.3 2.3 20.0 10.0 12.1 4.2 66.6 13.4 35.4 14.1 21.0 0.1 0.6 0.0 8.3 10.4 4.8 24.8 16.9 15.4 32.0 15.8 294.5 44.6 84.8 50.2 0.7 10.4 4.3 0.3 1.1 1.1 0.5 2.3 0.7 0.6 0.6 0.3 0.4 0.3 0.9 1.9 0.9 0.5 2.8 0.7 0.3 4.2 12.3 1.2 8.9 8.0 4.6 2.9 5.0 2.5 3.3 8.4 5.9 37.1 9.6 46.1 19.9 31.0 31.7 5.7 1.2 5.2 28.1 18.8 5.8 4.4 44.3 6.9 106.7 0.0 6.8 40.6 23.3 5.9 9.4 232.5 5.9 63.9 42.1 48.0 40.4 165.0 37.8 12.4 98.4 18.8 10.7 3.8 24.0 97.5 270.5 101.1 0.0 79.4 61.1 0.0 84.6 91.2 39.3 26.4 98.0 28.4 128.4 13.5 1.7 42.2 4.5 3.7 14.8 18.9 4.1 147.5 5.3 92.2 33.5 4.6 5.0 6.6 12.9 27.8 2.8 3.9 3.4 27.8 6.2 24.3 14.6 18.9 9.7 MAOB ENSG00000069535 "Monoamine oxidase B" P27338 X 43766610-43882450 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 317.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 120.6;granulocytes: 137.8;Hepatocytes: 221.1;Peritubular cells: 95.2;Proximal enterocytes: 178.8;Proximal tubular cells: 182.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Hep G2: 41.4;SiHa: 78.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002328, CAB037200" Enhanced NA NA 110000 "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB037200: AB_1841012, HPA002328: AB_1854062" "unprognostic (1.19e-2)" "unprognostic (1.36e-1)" "unprognostic (5.16e-2)" "unprognostic (1.85e-2)" "unprognostic (4.39e-2)" "unprognostic (2.69e-2)" "unprognostic (5.61e-2)" "unprognostic (4.37e-2)" "unprognostic (1.56e-1)" "unprognostic (1.04e-2)" "unprognostic (1.20e-1)" "unprognostic (1.54e-2)" "unprognostic (9.74e-2)" "unprognostic (5.35e-3)" "unprognostic (1.48e-2)" "unprognostic (3.53e-1)" "unprognostic (1.90e-3)" 78.0 51.1 99.3 6.5 102.8 0.1 45.7 89.1 117.7 32.3 83.5 46.5 73.5 119.4 55.0 31.4 98.0 17.3 97.8 93.9 149.1 124.2 317.6 33.0 6.1 143.8 134.2 155.4 10.9 15.6 25.9 11.2 125.9 82.9 16.5 13.9 78.5 155.5 114.6 9.9 79.0 103.3 115.8 2.4 23.7 9.0 145.2 3.8 5.6 65.1 7.1 28.3 25.4 115.8 0.0 1.0 0.1 0.0 0.6 0.1 0.3 0.0 0.0 0.0 0.0 5.4 4.7 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 8.1 41.4 0.0 0.2 0.0 0.3 0.1 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.3 3.5 0.0 0.0 0.0 0.0 0.4 4.0 0.0 0.1 1.1 78.2 0.0 0.5 0.6 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 99.3 102.8 89.1 117.7 93.9 149.1 143.8 134.2 125.9 115.8 145.2 115.8 5.9 0.0 4.1 53.5 0.4 5.5 0.4 1.2 1.8 1.4 3.5 22.4 120.6 52.9 1.9 5.5 4.2 0.4 0.0 10.2 62.6 20.1 0.4 26.4 81.6 10.3 0.0 2.7 36.9 2.8 0.5 17.0 16.3 6.0 137.8 69.6 7.5 221.1 1.5 15.2 7.6 6.4 12.2 4.3 3.6 2.1 46.0 1.8 7.2 9.4 0.0 27.2 0.0 11.6 1.3 7.9 7.8 95.2 0.3 0.6 178.8 182.6 11.8 1.0 13.1 2.6 18.4 0.3 0.4 2.3 4.0 0.4 5.5 0.5 10.5 0.5 MAP2K6 "MAPKK6, MEK6, MKK6, PRKMK6, SAPKK3" ENSG00000108984 "Mitogen-activated protein kinase kinase 6" P52564 17 69414697-69553865 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 40.5" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 53.9;Glandular and luminal cells: 82.7;Oligodendrocytes: 52.5" "Cancer enhanced" "Detected in many" "endometrial cancer: 8.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "classical monocyte: 22.0;neutrophil: 45.9;plasmacytoid DC: 78.3" "Group enriched" "Detected in all" 9 "dendritic cells: 78.3;granulocytes: 45.9;monocytes: 22.0" "Cell line enhanced" "Detected in many" "A549: 40.0;AN3-CA: 21.4;HUVEC TERT2: 28.4;MOLT-4: 21.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007744, HPA031134" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" "CAB007744: AB_562318, HPA031134: AB_10603016" "prognostic favorable (2.27e-6)" "unprognostic (2.24e-1)" "unprognostic (8.46e-2)" "unprognostic (4.10e-2)" "unprognostic (3.75e-2)" "unprognostic (1.23e-1)" "unprognostic (7.61e-3)" "unprognostic (9.52e-2)" "unprognostic (3.67e-1)" "unprognostic (4.09e-3)" "prognostic favorable (7.52e-4)" "unprognostic (3.61e-2)" "unprognostic (2.29e-2)" "unprognostic (7.48e-2)" "unprognostic (9.43e-2)" "unprognostic (1.39e-1)" "unprognostic (2.03e-2)" 5.2 1.3 4.2 8.4 4.0 15.9 20.4 11.6 4.0 27.0 7.6 30.7 10.3 6.1 3.2 3.1 4.5 7.2 1.4 2.7 6.2 5.5 12.2 1.8 8.0 5.4 3.8 3.1 8.3 0.3 1.6 1.6 3.9 3.3 31.7 5.8 2.5 3.1 40.5 2.0 10.8 3.3 4.4 4.0 7.4 1.3 5.7 11.5 3.3 21.1 5.9 3.3 1.2 7.7 0.1 40.0 17.6 21.4 7.4 4.0 2.5 0.3 5.8 1.6 2.4 1.2 1.7 1.1 14.2 0.8 1.3 1.9 6.1 0.8 0.5 1.3 3.2 0.1 10.3 11.4 7.4 1.7 1.3 19.0 0.5 0.3 0.0 1.4 28.4 5.3 0.1 2.5 0.0 0.3 21.6 0.7 12.5 0.9 7.3 7.7 1.8 0.5 7.8 5.4 7.8 11.8 1.7 1.3 3.9 9.3 5.4 2.3 5.1 1.9 2.3 1.6 0.5 1.7 2.2 0.5 1.6 2.5 1.5 2.5 22.0 4.0 2.8 2.6 5.0 4.1 3.1 3.5 7.1 5.2 3.6 3.4 45.9 4.7 1.1 78.3 5.0 6.2 4.2 4.0 11.6 4.0 2.7 6.2 5.4 3.8 3.9 4.4 5.7 7.7 11.2 3.2 6.7 27.7 7.7 2.7 4.1 0.8 8.6 5.2 14.3 29.1 1.3 5.7 3.6 0.0 2.1 9.7 29.2 42.3 23.5 1.9 10.2 53.9 11.5 7.9 45.6 5.0 26.0 4.1 6.6 5.0 9.2 82.7 1.3 13.4 4.2 2.5 6.2 3.3 22.4 22.9 0.0 6.8 7.4 2.9 4.4 6.9 3.6 24.4 9.6 31.8 10.3 32.6 52.5 1.1 16.7 3.8 10.7 1.3 14.5 1.5 4.2 4.2 0.0 3.9 5.7 0.1 1.8 4.8 4.3 0.8 13.3 1.4 30.6 2.8 MAP4K1 HPK1 ENSG00000104814 "Mitogen-activated protein kinase kinase kinase kinase 1" Q92918 19 38587641-38618882 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.1;lymphoid tissue: 56.9" "Cell type enhanced" "Detected in many" "B-cells: 42.6;dendritic cells: 42.6;Langerhans cells: 27.8;Plasma cells: 30.4;Rod photoreceptor cells: 77.9;T-cells: 43.6" "Cancer enhanced" "Detected in all" "testis cancer: 15.2" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 45.2;HDLM-2: 46.4;Karpas-707: 46.9;REH: 25.5;RPMI-8226: 29.8;U-266/70: 36.0;U-266/84: 38.2;U-698: 57.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA007419, CAB007754" Enhanced Approved "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB007754: AB_562299, HPA007419: AB_1853778" "unprognostic (1.99e-3)" "prognostic favorable (6.17e-5)" "unprognostic (9.50e-3)" "unprognostic (3.27e-1)" "unprognostic (6.03e-2)" "prognostic favorable (3.26e-4)" "unprognostic (4.88e-3)" "unprognostic (5.32e-3)" "unprognostic (2.79e-1)" "unprognostic (2.51e-1)" "unprognostic (3.92e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (7.99e-10)" "unprognostic (1.72e-1)" "unprognostic (1.83e-1)" "unprognostic (3.18e-2)" "unprognostic (1.50e-2)" 2.7 1.5 0.6 14.6 0.7 9.2 1.7 0.7 1.2 1.6 0.7 5.0 2.7 1.3 0.8 2.8 1.8 2.3 1.7 0.7 0.8 2.7 3.0 6.2 32.2 1.0 0.8 0.9 1.2 0.2 1.8 1.8 0.9 2.5 2.3 16.1 2.8 0.5 0.8 1.9 30.1 0.9 0.8 56.9 3.1 1.5 0.9 13.1 3.2 0.2 29.3 2.9 2.1 0.9 0.2 0.3 0.2 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 45.2 0.7 0.0 0.0 0.1 0.1 0.0 0.0 46.4 0.3 9.8 0.1 0.1 0.0 3.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 21.3 0.2 46.9 0.1 0.3 11.0 12.0 1.4 0.3 0.1 25.5 0.1 29.8 0.0 0.0 0.4 0.1 0.1 0.2 0.1 0.3 0.2 10.8 0.1 0.1 0.3 0.1 0.1 36.0 38.2 57.8 0.0 13.5 0.1 2.9 4.9 2.0 18.9 9.4 17.4 22.7 15.8 20.1 23.9 15.5 8.6 12.1 0.5 6.1 5.7 22.2 22.2 12.1 0.6 0.7 0.7 1.2 0.7 0.8 1.0 0.8 0.9 0.8 0.9 0.9 0.7 3.2 4.9 0.3 42.6 2.3 0.2 0.4 1.2 6.7 0.7 1.0 0.9 0.0 0.6 0.0 12.5 0.2 42.6 0.1 0.0 0.0 0.0 0.3 0.2 1.6 0.0 5.5 0.7 0.2 0.3 1.5 2.0 0.3 15.8 0.4 1.1 1.1 2.6 1.7 1.0 0.1 0.0 8.8 27.8 0.2 0.0 11.6 3.6 1.9 10.3 11.5 15.5 1.0 0.5 0.0 0.0 0.0 30.4 0.3 0.0 0.2 0.0 77.9 0.0 1.0 0.4 0.7 6.4 0.6 1.0 0.1 43.6 0.3 0.3 0.1 MARCO "SCARA2, SR-A6" ENSG00000019169 "Macrophage receptor with collagenous structure" Q9UEW3 2 118942194-118994660 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 94.9;lung: 199.6;lymphoid tissue: 87.9" "Cell type enriched" "Detected in many" 6 "Kupffer cells: 1269.8" "Cancer enhanced" "Detected in many" "lung cancer: 21.6" "Group enriched" "Detected in many" 4 "cerebral cortex: 4.1;thalamus: 12.6" "Group enriched" "Detected in some" 4 "classical monocyte: 33.7;intermediate monocyte: 56.5" "Lineage enriched" "Detected in many" 5 "monocytes: 56.5" "Cell line enhanced" "Detected in some" "HaCaT: 1.7;THP-1: 2.5;U-2 OS: 2.6;U-266/70: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA063793 Enhanced Approved "Golgi apparatus,Vesicles" NA NA 30000000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "Golgi apparatus" Vesicles "HPA063793: AB_2685123" "unprognostic (1.30e-1)" "unprognostic (1.61e-1)" "unprognostic (5.96e-3)" "unprognostic (3.36e-2)" "unprognostic (1.71e-2)" "unprognostic (3.58e-2)" "unprognostic (3.67e-1)" "unprognostic (1.06e-1)" "unprognostic (2.95e-1)" "unprognostic (2.83e-1)" "unprognostic (6.27e-3)" "unprognostic (5.13e-2)" "unprognostic (2.24e-3)" "unprognostic (1.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.40e-1)" "unprognostic (6.55e-2)" 64.7 31.1 0.4 87.9 1.4 3.4 7.4 0.7 4.1 0.7 4.4 5.7 2.0 0.7 1.3 2.4 25.5 2.4 19.0 0.9 1.0 1.6 94.9 199.6 17.7 1.2 1.7 7.5 0.8 0.3 1.5 2.8 1.9 1.8 2.1 0.0 4.4 2.3 1.5 2.5 3.1 29.8 1.2 37.1 3.5 2.0 12.6 1.3 1.5 5.0 1.1 25.2 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 2.6 0.4 0.0 1.6 0.0 0.0 0.0 0.5 0.0 0.0 33.7 0.0 0.0 56.5 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.7 0.0 7.2 1.0 0.0 9.2 0.4 1.4 0.7 4.1 0.9 1.0 1.2 1.7 1.9 1.2 12.6 0.7 0.7 25.6 45.1 0.0 1.0 1.1 0.1 0.0 0.0 0.0 3.4 1.8 0.4 1.5 16.7 3.7 0.0 0.7 1.4 0.1 0.0 3.9 0.0 0.0 0.0 5.2 0.0 8.0 0.0 0.2 1.1 2.6 0.0 0.0 12.6 0.0 11.4 3.4 169.6 0.0 0.0 0.0 0.0 1269.8 46.4 0.1 0.0 199.3 0.0 2.8 23.2 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.5 0.1 0.0 0.2 13.1 0.0 0.0 0.5 0.2 0.0 0.3 0.0 0.9 1.9 4.1 0.0 0.0 0.1 MASP2 MASP1P1 ENSG00000009724 "Mannan binding lectin serine peptidase 2" O00187 1 11026523-11047239 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 64 "liver: 476.5" "Cell type enriched" "Detected in some" 52 "Hepatocytes: 658.6" "Cancer enriched" "Detected in some" 71 "liver cancer: 41.9" "Region enriched" "Detected in single" 9 "cerebellum: 6.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "Hep G2: 16.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA029313, HPA029314" Uncertain Supported "Golgi apparatus" "Secreted to blood" NA NA 340000000 820000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "HPA029313: AB_10669654, HPA029314: AB_10670029" "unprognostic (7.00e-2)" "unprognostic (8.37e-2)" "unprognostic (2.75e-2)" "unprognostic (2.89e-1)" "unprognostic (1.86e-1)" "unprognostic (3.26e-3)" "prognostic favorable (1.60e-4)" "unprognostic (2.92e-3)" "unprognostic (3.13e-2)" "unprognostic (4.04e-2)" "unprognostic (6.90e-3)" "unprognostic (8.30e-4)" "unprognostic (7.14e-2)" "unprognostic (3.91e-1)" "unprognostic (2.62e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-4)" 2.1 1.2 0.0 1.7 0.0 7.4 2.2 6.4 0.7 2.4 0.0 2.7 1.6 2.8 0.0 1.2 2.7 1.2 1.3 0.1 0.0 1.0 476.5 1.8 2.7 0.0 0.0 2.9 2.9 0.0 2.3 0.6 0.2 1.6 0.0 6.9 2.5 0.0 5.1 5.3 3.4 0.0 0.0 2.5 2.4 1.5 0.0 0.0 1.9 0.0 0.0 2.1 1.6 0.4 0.5 0.3 2.6 1.6 0.0 0.1 0.4 0.7 0.0 0.0 0.0 1.2 1.0 2.3 0.6 0.0 0.5 0.7 0.0 0.0 0.0 0.6 2.3 1.3 2.7 16.4 0.0 2.0 1.5 0.0 0.0 0.1 0.0 1.8 0.0 1.7 0.7 0.5 0.0 0.5 0.6 1.1 0.3 0.2 0.7 1.6 0.9 0.6 0.0 1.3 1.7 0.7 0.9 0.4 0.4 1.6 0.6 1.2 1.2 0.9 0.5 0.8 0.5 0.5 0.9 1.5 0.5 1.7 0.4 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 6.4 0.7 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 4.6 1.1 0.9 0.2 0.0 0.6 0.2 0.2 0.0 0.5 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.9 0.0 5.3 9.5 0.0 0.0 0.1 0.0 0.1 1.3 0.0 8.2 658.6 0.1 0.0 8.3 0.0 0.0 12.6 0.3 0.0 0.0 0.0 1.8 1.9 0.0 0.1 0.0 8.0 10.4 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.7 0.4 0.0 0.7 0.2 0.0 0.0 0.4 0.6 0.0 0.8 0.1 0.0 0.1 MBOAT2 "FLJ14415, FLJ90298, OACT2" ENSG00000143797 "Membrane bound O-acyltransferase domain containing 2" Q6ZWT7 2 8852690-9003709 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 171.1;Erythroid cells: 162.6;Excitatory neurons: 134.6;Horizontal cells: 141.3;Oligodendrocyte precursor cells: 177.4;Oligodendrocytes: 230.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 4.7;eosinophil: 1.7;neutrophil: 4.0" "Lineage enriched" "Detected in single" 10 "granulocytes: 4.7" "Cell line enhanced" "Detected in many" "SK-BR-3: 41.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014836 Uncertain Approved Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA014836: AB_1854745" "unprognostic (2.49e-1)" "unprognostic (2.17e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (2.13e-9)" "unprognostic (1.30e-1)" "unprognostic (2.32e-2)" "unprognostic (2.38e-1)" "unprognostic (3.97e-3)" "unprognostic (3.09e-1)" "unprognostic (3.00e-1)" "unprognostic (1.03e-3)" "unprognostic (1.70e-1)" "unprognostic (5.90e-2)" "unprognostic (2.23e-1)" "unprognostic (3.04e-2)" "unprognostic (6.66e-2)" "prognostic unfavorable (5.32e-4)" 2.2 2.1 16.4 2.4 23.6 26.9 9.0 20.5 18.4 7.7 26.2 7.6 2.4 4.6 2.7 15.8 2.9 3.6 4.6 18.9 21.9 7.0 0.8 6.7 1.9 21.8 22.2 5.8 1.4 29.3 5.4 3.2 22.4 14.4 8.5 15.6 5.7 2.3 1.1 11.6 3.7 3.9 20.6 2.4 6.1 2.1 21.9 2.4 4.5 1.1 4.8 3.8 8.4 29.3 14.0 4.2 12.7 5.4 5.6 12.5 7.3 6.5 2.4 8.5 5.6 1.1 21.9 3.9 7.5 15.9 6.8 10.5 11.4 13.5 12.6 12.3 19.0 16.7 5.9 0.0 6.9 0.0 5.0 9.1 7.8 8.1 5.6 18.5 4.5 5.5 14.4 3.0 7.5 3.6 4.9 0.3 5.0 6.4 15.8 7.4 20.0 0.1 12.6 2.0 7.6 23.0 6.9 41.1 6.6 6.2 7.7 4.8 2.5 14.7 7.7 11.6 19.0 1.1 0.4 4.3 23.3 2.4 5.1 4.7 0.4 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 4.0 0.0 0.1 0.1 0.0 0.2 16.4 23.6 20.5 18.4 18.9 21.9 21.8 22.2 22.4 20.6 21.9 29.3 7.7 19.2 12.7 171.1 1.7 3.3 4.6 33.1 0.6 20.6 18.1 12.1 12.2 7.2 54.7 40.5 8.4 3.9 1.1 28.2 5.9 5.6 9.7 3.2 19.4 13.4 37.6 162.6 134.6 1.5 1.4 12.7 21.4 2.9 8.2 14.7 4.6 0.2 1.8 141.3 107.8 59.3 32.6 1.9 17.7 12.7 5.3 5.0 14.2 33.7 29.0 98.7 0.0 177.4 230.5 88.1 42.9 7.5 0.3 19.5 1.6 10.4 45.7 8.8 6.6 10.5 15.2 12.1 24.8 24.4 5.1 1.9 2.0 1.9 12.7 66.4 MCCC2 MCCB ENSG00000131844 "Methylcrotonoyl-CoA carboxylase 2" Q9HCC0 5 71587288-71658706 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 120.5" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 107.0" "Cancer enhanced" "Detected in all" "prostate cancer: 81.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038300, HPA038301, HPA061546" Enhanced Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA038300: AB_2675941, HPA038301: AB_10670661, HPA061546: AB_2684557" "unprognostic (2.39e-1)" "unprognostic (6.89e-3)" "prognostic favorable (3.62e-4)" "unprognostic (1.79e-2)" "unprognostic (1.89e-2)" "unprognostic (8.07e-2)" "prognostic favorable (1.70e-4)" "unprognostic (1.01e-1)" "unprognostic (3.37e-1)" "unprognostic (5.39e-2)" "unprognostic (2.90e-1)" "unprognostic (2.38e-1)" "prognostic favorable (6.43e-8)" "unprognostic (1.27e-1)" "unprognostic (1.29e-1)" "unprognostic (5.15e-2)" "unprognostic (3.47e-2)" 21.3 47.6 13.4 13.5 13.7 6.0 60.0 12.4 15.5 21.3 24.9 30.5 27.2 14.4 38.9 25.4 17.2 15.2 54.9 12.0 13.1 73.3 120.5 13.4 17.8 14.8 13.4 14.2 24.6 32.8 14.1 14.2 14.8 48.2 35.9 12.2 28.2 20.6 34.4 19.8 20.7 11.7 16.3 15.6 25.8 8.6 16.0 14.2 44.6 35.4 21.5 27.0 15.0 18.4 38.5 52.4 21.4 82.5 22.4 23.0 36.9 16.4 29.4 35.7 25.7 91.1 46.9 90.4 62.8 25.9 28.0 30.8 37.8 58.8 44.3 47.6 45.6 48.2 24.7 100.5 39.2 24.4 42.8 29.5 30.1 32.6 25.8 15.8 31.7 24.9 63.2 31.6 24.9 103.0 0.3 42.9 29.0 33.2 27.2 46.3 64.5 130.9 92.5 66.9 32.9 36.7 80.1 111.8 38.8 10.1 92.7 59.6 22.7 14.4 22.1 26.1 49.9 22.4 46.2 54.6 23.7 66.3 36.6 2.0 8.4 1.9 6.5 13.5 8.5 9.7 8.4 7.4 19.4 9.9 8.3 9.1 1.3 14.7 8.1 8.1 12.1 8.3 13.4 13.7 12.4 15.5 12.0 13.1 14.8 13.4 14.8 16.3 16.0 18.4 9.1 16.0 23.6 27.4 26.8 13.3 17.5 20.2 22.2 12.6 54.9 28.3 61.5 20.0 22.3 16.5 6.2 48.5 17.6 26.3 21.5 20.6 4.3 94.0 24.0 15.1 29.5 13.9 22.2 18.2 23.0 13.1 30.1 107.0 12.7 22.7 9.7 93.1 18.0 3.3 21.6 22.8 8.2 12.1 11.2 9.8 13.7 14.0 12.4 11.2 17.9 15.4 20.6 30.2 28.0 15.3 17.0 20.3 27.2 29.6 23.6 59.1 17.7 10.8 6.6 15.2 9.0 4.2 12.0 35.9 13.8 63.6 17.9 30.9 33.9 20.9 MCEE "GLOD2, MCE" ENSG00000124370 "Methylmalonyl-CoA epimerase" Q96PE7 2 71109684-71130239 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 92.0;Proximal tubular cells: 77.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035196 Approved Nucleoli "Intracellular and membrane" No No 29000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 30: Mammary glandular cells - Lactation" Nucleoli "HPA035196: AB_10601871" "unprognostic (7.65e-2)" "unprognostic (8.20e-2)" "unprognostic (3.01e-1)" "unprognostic (2.25e-1)" "unprognostic (1.35e-1)" "prognostic favorable (4.76e-4)" "prognostic favorable (5.78e-4)" "unprognostic (4.86e-3)" "unprognostic (6.48e-2)" "unprognostic (1.08e-1)" "unprognostic (7.43e-3)" "unprognostic (8.59e-2)" "unprognostic (9.40e-3)" "unprognostic (4.90e-2)" "unprognostic (3.55e-1)" "unprognostic (6.51e-2)" "unprognostic (5.38e-2)" 17.8 30.0 8.9 12.3 9.7 9.1 32.7 10.5 12.5 22.1 15.4 20.1 20.1 13.1 30.5 26.3 14.8 14.2 35.9 8.9 9.4 33.7 69.8 13.7 14.7 9.5 9.1 18.5 36.1 35.6 24.1 17.6 9.9 23.9 23.9 12.3 42.8 17.8 36.5 28.4 16.9 12.2 9.7 16.0 23.5 6.0 9.4 13.3 14.1 61.7 15.5 16.5 21.9 11.7 12.1 5.2 10.6 7.6 34.3 46.6 30.2 18.5 23.3 9.2 13.9 14.7 14.8 18.7 5.5 18.5 7.0 12.5 12.4 9.6 9.5 17.1 10.7 12.7 16.3 42.5 19.5 14.5 10.3 31.3 13.5 6.2 12.3 20.5 10.6 14.6 17.1 31.9 9.1 15.5 10.9 16.9 9.6 33.1 14.6 12.8 12.3 35.2 14.8 10.4 11.9 8.8 6.9 40.1 18.1 12.1 31.7 13.4 13.7 10.6 8.3 10.9 7.5 30.7 13.1 20.0 17.5 23.7 9.9 20.3 23.2 27.6 15.4 25.6 21.9 21.6 19.3 15.5 19.9 16.7 17.6 15.0 6.1 16.5 25.3 23.9 35.3 14.6 8.9 9.7 10.5 12.5 8.9 9.4 9.5 9.1 9.9 9.7 9.4 11.7 11.1 25.6 13.4 13.7 12.8 8.5 10.5 18.4 21.6 2.6 37.5 27.3 75.2 25.8 18.2 5.5 2.1 36.2 11.2 14.0 92.0 13.3 1.1 17.2 16.2 9.0 9.0 12.0 13.3 18.4 36.8 23.3 17.3 20.2 0.0 5.2 12.8 73.0 15.1 5.0 14.5 32.5 18.3 10.4 8.7 1.0 29.2 9.4 14.2 14.0 9.1 7.3 5.2 16.1 20.8 9.6 16.2 17.7 42.0 11.0 35.0 77.1 19.4 8.6 26.3 12.7 17.9 3.7 5.1 25.6 20.9 11.4 10.1 16.9 23.0 11.9 MCEMP1 "C19orf59, MGC132456" ENSG00000183019 "Mast cell expressed membrane protein 1" Q8IX19 19 7676628-7679826 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "bone marrow: 65.9;lung: 74.2;lymphoid tissue: 35.1" "Cell type enriched" "Detected in some" 4 "Macrophages: 147.5" "Cancer enhanced" "Detected in many" "lung cancer: 3.7" "Region enhanced" "Detected in single" "cerebral cortex: 2.1" "Group enriched" "Detected in some" 5 "classical monocyte: 102.1;neutrophil: 45.9" "Group enriched" "Detected in many" 5 "granulocytes: 45.9;monocytes: 102.1" "Group enriched" "Detected in some" 6 "THP-1: 53.7;U-937: 166.6" "Region enhanced" "Detected in single" "cerebellum: 1.3" "Not detected" "Not detected" HPA014731 Enhanced Supported "Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "HPA014731: AB_1845619" "unprognostic (4.84e-2)" "unprognostic (9.81e-4)" "unprognostic (2.41e-1)" "unprognostic (4.36e-2)" "unprognostic (8.85e-3)" "unprognostic (2.62e-3)" "unprognostic (5.57e-3)" "unprognostic (1.42e-1)" "unprognostic (2.19e-1)" "unprognostic (4.36e-2)" "unprognostic (1.77e-2)" "unprognostic (3.50e-1)" "unprognostic (2.69e-5)" "unprognostic (1.15e-2)" "unprognostic (7.37e-2)" "unprognostic (1.93e-2)" "unprognostic (7.95e-2)" 4.0 0.5 0.0 19.7 0.0 65.9 0.5 0.0 2.1 0.1 0.0 0.4 0.2 0.1 0.0 0.5 1.7 0.6 1.3 0.0 0.0 0.7 1.5 74.2 0.1 0.0 0.0 0.2 0.7 0.0 0.2 1.8 0.9 0.5 0.1 0.0 0.8 0.0 0.3 0.1 0.6 5.1 0.0 35.1 0.9 0.2 0.7 0.9 0.4 1.5 0.1 4.7 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.0 1.4 17.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 53.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 166.6 0.0 0.0 102.1 2.8 0.2 6.0 0.0 0.0 0.3 0.0 14.9 0.0 0.0 0.3 45.9 0.6 0.4 0.9 0.2 38.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.9 0.0 0.7 0.0 0.4 19.2 34.5 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.5 11.2 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.1 0.0 0.0 2.2 0.0 3.6 0.0 0.0 1.0 2.9 0.0 0.0 7.6 0.0 0.0 0.3 28.8 0.0 0.0 0.0 0.0 28.3 0.0 0.1 0.0 147.5 0.0 0.0 26.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.2 5.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.8 2.9 0.0 0.0 0.1 MCOLN2 "FLJ36691, TRP-ML2, TRPML2" ENSG00000153898 "Mucolipin 2" Q8IZK6 1 84925583-84997113 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Calcium transport, Immunity, Innate immunity, Ion transport, Protein transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.1;lymphoid tissue: 13.1" "Cell type enhanced" "Detected in many" "B-cells: 26.3;dendritic cells: 43.6;Distal enterocytes: 31.4;Early spermatids: 53.1;Langerhans cells: 100.8;monocytes: 32.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 29.7" "Group enriched" "Detected in many" 14 "B-cells: 10.3;dendritic cells: 29.7;T-cells: 8.9" "Cell line enhanced" "Detected in many" "Daudi: 21.9;HAP1: 14.7;HDLM-2: 26.9;HEK 293: 13.6;THP-1: 28.5;U-698: 18.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA019114 Uncertain NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "HPA019114: AB_1853645" "unprognostic (3.02e-2)" "unprognostic (5.67e-2)" "unprognostic (3.07e-1)" "unprognostic (1.44e-1)" "unprognostic (2.47e-1)" "unprognostic (5.66e-3)" "unprognostic (2.38e-1)" "prognostic favorable (2.56e-4)" "unprognostic (8.92e-2)" "unprognostic (1.48e-2)" "unprognostic (6.84e-2)" "unprognostic (2.21e-2)" "unprognostic (3.12e-4)" "unprognostic (3.68e-2)" "unprognostic (4.69e-2)" "unprognostic (1.24e-1)" "unprognostic (4.23e-2)" 0.7 8.8 0.2 5.3 0.2 2.9 1.0 1.0 0.4 1.1 0.7 10.2 1.7 1.0 4.0 0.7 2.6 1.6 0.4 0.3 0.1 1.1 0.7 5.4 12.9 0.4 0.1 0.5 0.8 1.1 0.6 2.6 0.3 0.7 15.1 0.1 0.8 0.2 0.2 2.1 5.5 0.6 0.1 6.7 2.1 1.5 0.3 2.3 0.5 0.2 13.1 1.6 0.7 0.5 1.5 1.6 0.0 4.0 0.8 0.2 0.3 1.0 5.5 1.6 2.0 0.0 0.1 21.9 0.5 0.0 2.6 0.1 14.7 1.8 1.5 26.9 13.6 1.9 0.4 0.0 1.3 0.0 1.8 0.3 0.0 1.3 1.0 0.1 0.0 5.1 0.0 0.0 0.3 0.5 0.3 0.0 1.6 0.0 2.9 0.0 3.3 0.0 0.1 0.2 0.9 0.0 0.1 0.2 9.2 0.2 2.4 28.5 0.1 1.3 2.1 0.0 4.2 0.0 0.0 18.5 1.2 0.0 4.0 0.1 0.3 0.0 5.9 1.1 2.1 10.3 5.0 8.9 7.1 3.7 0.6 4.5 0.2 0.4 0.2 29.7 0.2 2.6 0.2 0.2 1.0 0.4 0.3 0.1 0.4 0.1 0.3 0.1 0.3 0.5 0.4 0.0 0.6 0.0 26.3 4.5 0.4 0.1 1.2 0.0 1.1 1.8 0.5 0.0 1.3 1.8 0.0 0.1 43.6 31.4 0.0 0.1 53.1 12.3 6.0 0.4 2.4 1.3 0.9 1.4 0.1 1.5 1.5 24.5 0.0 0.1 0.7 0.0 0.7 0.0 0.5 4.5 0.0 1.3 100.8 19.6 0.0 14.4 8.8 2.8 32.3 0.0 1.0 0.0 1.4 0.4 4.7 0.0 13.8 0.6 0.0 2.3 1.5 0.0 0.0 0.7 0.3 1.6 4.3 0.0 3.3 0.3 21.8 1.6 5.4 0.1 MECOM "EVI1, KMT8E, MDS1, MDS1-EVI1, PRDM3" ENSG00000085276 "MDS1 and EVI1 complex locus" Q03112 3 169083499-169663775 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 73.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 184.8;Collecting duct cells: 125.0;Gastric mucus-secreting cells: 111.1;Glandular and luminal cells: 107.7;Microglial cells: 346.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 55.5;RPTEC TERT1: 71.2;RT4: 119.6;TIME: 53.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046537 Supported Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "HPA046537: AB_2679689" "unprognostic (4.09e-2)" "unprognostic (1.96e-1)" "unprognostic (3.24e-3)" "unprognostic (7.29e-2)" "unprognostic (2.87e-2)" "unprognostic (2.53e-1)" "unprognostic (1.83e-2)" "unprognostic (4.77e-3)" "unprognostic (1.53e-2)" "unprognostic (3.27e-3)" "prognostic unfavorable (2.59e-4)" "unprognostic (1.87e-1)" "unprognostic (2.60e-3)" "unprognostic (6.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.81e-2)" "unprognostic (3.37e-3)" 16.0 0.9 7.3 7.3 7.2 1.4 12.3 8.5 7.3 21.3 2.4 24.9 19.8 17.3 4.4 13.5 23.4 8.3 13.0 4.9 6.3 41.3 1.4 25.5 1.5 9.1 7.2 2.3 23.3 1.7 4.2 17.4 8.9 6.9 30.0 1.8 8.8 8.0 4.3 2.6 10.2 8.0 4.1 6.2 73.3 3.0 8.1 2.0 5.7 12.0 5.3 30.4 7.5 6.3 25.8 0.7 0.9 0.2 3.7 2.7 1.1 3.7 4.2 1.1 2.2 10.7 26.1 0.9 39.1 0.6 5.5 13.4 10.2 15.7 3.1 1.4 16.6 16.7 7.6 1.1 0.4 0.3 5.1 5.7 2.2 1.0 12.1 12.0 55.5 1.4 13.0 1.8 10.3 9.8 0.9 0.4 1.7 13.5 6.6 9.8 13.1 0.3 71.2 119.6 1.0 3.1 1.3 6.7 0.3 1.5 7.1 1.1 53.4 9.7 6.6 2.5 16.9 1.4 0.7 0.9 4.8 1.0 1.6 0.9 0.4 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.3 0.4 0.5 1.6 0.1 0.0 7.3 7.2 8.5 7.3 4.9 6.3 9.1 7.2 8.9 4.1 8.1 6.3 80.2 60.9 184.8 16.0 0.6 2.2 33.3 29.4 10.2 0.0 1.2 0.9 11.4 2.8 69.6 125.0 0.0 1.1 0.1 25.5 52.8 1.6 10.4 71.9 5.8 70.5 19.9 7.4 10.3 75.4 0.2 4.8 111.1 107.7 9.5 0.8 69.3 0.2 0.0 0.0 9.1 29.0 20.3 0.6 1.9 3.2 0.3 2.6 1.8 346.6 1.0 0.0 0.0 6.0 13.8 49.8 19.3 0.0 0.3 13.9 6.2 0.7 53.2 0.1 0.0 1.4 5.7 3.0 1.2 39.4 1.4 0.4 1.3 0.5 53.9 45.4 MEGF6 EGFL3 ENSG00000162591 "Multiple EGF like domains 6" O75095 1 3487951-3611508 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 22.4;Alveolar cells type 2: 20.6;Basal keratinocytes: 18.4;Basal squamous epithelial cells: 23.3;Melanocytes: 19.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ: 51.1;HeLa: 56.3;hTERT-RPE1: 69.7;U-2197: 55.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052129 Uncertain Approved "Microtubules,Cytokinetic bridge" "Secreted to blood" Yes No 1700000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Microtubules "Cytokinetic bridge" "HPA052129: AB_2681739" "unprognostic (1.95e-1)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.16e-2)" "unprognostic (2.38e-1)" "prognostic favorable (6.57e-4)" "unprognostic (1.19e-1)" "unprognostic (4.16e-2)" "unprognostic (1.73e-1)" "unprognostic (1.47e-1)" "unprognostic (2.90e-2)" "unprognostic (2.03e-1)" "unprognostic (3.09e-3)" "unprognostic (1.60e-1)" "unprognostic (1.64e-1)" "unprognostic (9.51e-2)" "unprognostic (3.43e-2)" 25.9 4.3 2.9 3.9 2.7 10.8 20.0 2.6 2.8 14.5 1.4 14.1 2.1 9.6 1.4 13.2 28.9 11.2 14.2 1.9 3.2 5.9 5.0 22.1 5.5 3.5 5.8 18.0 6.5 0.4 4.1 2.8 3.6 26.5 1.1 1.8 19.3 4.7 4.8 44.6 10.0 1.4 2.1 10.7 10.1 3.3 3.7 3.4 11.6 1.9 3.4 11.0 22.8 1.9 11.6 14.1 4.3 6.6 0.4 0.3 1.0 51.1 14.1 5.2 1.6 3.3 10.4 0.0 13.8 24.6 4.4 6.7 0.0 0.5 1.7 0.0 0.4 0.0 56.3 3.3 0.0 0.2 0.9 0.1 0.6 0.4 0.8 69.7 5.6 0.1 0.0 0.0 0.1 6.0 0.0 10.9 2.7 3.3 0.9 2.2 3.0 6.2 1.1 3.8 3.8 3.1 18.8 1.1 6.4 11.4 4.9 1.5 2.2 19.6 1.7 55.6 3.9 0.2 0.0 0.0 0.1 0.0 0.0 1.0 0.0 1.9 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.3 0.0 0.8 0.0 0.0 0.0 0.8 0.1 2.9 2.7 2.6 2.8 1.9 3.2 3.5 5.8 3.6 2.1 3.7 1.9 5.0 22.4 20.6 8.8 2.7 18.4 7.1 3.9 23.3 0.8 3.6 3.0 3.3 5.7 4.4 1.8 0.0 0.2 0.4 0.6 0.0 3.6 0.2 1.4 0.6 7.0 0.0 4.8 6.5 1.4 1.3 9.4 6.6 5.0 1.3 9.8 16.8 0.9 1.0 0.0 7.2 1.4 0.0 0.3 7.5 0.5 11.5 2.8 19.6 5.6 0.7 14.7 1.0 4.5 5.2 4.5 0.1 3.4 0.4 4.0 0.5 1.2 0.3 1.2 0.0 0.5 2.7 0.3 1.1 7.6 11.4 0.4 3.6 0.1 1.1 2.7 MEI4 ENSG00000269964 "Meiotic double-stranded break formation protein 4" A8MW99 6 77650274-77927028 "Predicted intracellular proteins" "DNA recombination, Meiosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 4.0;testis: 3.7;thyroid gland: 2.1" "Cell type enriched" "Detected in some" 4 "Early spermatids: 86.1" "Cancer enhanced" "Detected in some" "renal cancer: 0.9;testis cancer: 1.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 43: Testis - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (3.47e-1)" "unprognostic (9.76e-2)" "unprognostic (2.51e-1)" "unprognostic (1.31e-1)" "unprognostic (1.11e-2)" "unprognostic (1.94e-1)" "unprognostic (1.88e-1)" "unprognostic (4.62e-2)" "unprognostic (9.70e-4)" "unprognostic (3.16e-1)" "unprognostic (2.86e-4)" "unprognostic (3.35e-2)" "unprognostic (4.17e-2)" "unprognostic (4.85e-2)" 0.1 0.7 0.4 0.0 0.4 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.5 0.2 0.6 4.0 0.8 0.0 0.0 1.0 0.5 0.0 2.0 0.1 1.0 0.0 1.2 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 3.7 0.6 0.0 2.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.3 0.2 0.2 0.6 1.0 0.5 1.2 0.5 0.6 0.6 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 86.1 0.0 0.0 0.1 0.0 0.0 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 3.0 0.0 0.0 0.0 0.0 21.3 0.3 0.0 0.0 9.4 0.0 0.6 0.0 2.0 2.5 0.1 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.0 0.0 0.0 3.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MEOX2 "GAX, MOX2" ENSG00000106511 "Mesenchyme homeobox 2" P50222 7 15611212-15686683 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 37.9;placenta: 42.1" "Cell type enhanced" "Detected in some" "Adipocytes: 84.7;Endothelial cells: 37.2;Leydig cells: 40.4;Peritubular cells: 25.2;Sertoli cells: 26.3;Smooth muscle cells: 27.0" "Cancer enriched" "Detected in many" 8 "glioma: 15.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AN3-CA: 248.8;U-138 MG: 62.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "medulla oblongata: 3.5;spinal cord: 9.5" HPA053793 Enhanced NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA053793: AB_2682264" "unprognostic (1.10e-1)" "unprognostic (4.72e-2)" "unprognostic (9.82e-3)" "unprognostic (4.22e-2)" "unprognostic (2.35e-2)" "unprognostic (1.36e-1)" "unprognostic (3.12e-2)" "unprognostic (1.21e-1)" "unprognostic (5.56e-2)" "unprognostic (1.47e-3)" "unprognostic (4.44e-1)" "unprognostic (2.34e-1)" "unprognostic (1.65e-5)" "unprognostic (3.67e-3)" "unprognostic (1.13e-1)" "unprognostic (5.86e-2)" "unprognostic (1.46e-4)" 37.9 1.1 0.6 2.9 0.3 0.0 26.2 0.3 0.7 4.3 0.2 5.7 0.4 2.9 2.4 2.4 5.0 6.1 11.8 0.3 0.7 0.5 0.7 12.9 9.1 2.2 0.9 2.4 1.6 1.2 1.2 42.1 1.0 1.9 1.9 0.2 4.4 1.5 9.9 6.9 2.2 4.5 0.7 0.9 2.3 2.3 1.0 3.3 8.6 13.3 5.3 6.1 4.8 0.5 0.0 0.0 0.0 248.8 2.4 8.5 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 32.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 62.9 0.0 25.4 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.3 0.7 0.3 0.7 2.2 0.9 1.0 0.7 1.0 0.5 84.7 0.0 0.5 0.7 0.3 8.2 0.0 0.0 0.6 0.0 0.5 1.3 2.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 37.2 0.0 0.0 3.8 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.7 0.2 0.1 0.0 3.7 0.0 0.0 0.0 9.6 0.2 40.4 0.3 3.6 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 25.2 0.0 0.1 0.0 0.0 0.0 0.0 26.3 1.5 27.0 0.1 0.1 0.1 7.0 0.1 0.8 0.7 0.0 0.0 MGAT4C HGNT-IV-H ENSG00000182050 "MGAT4 family member C" Q9UBM8 12 85955666-86838904 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "epididymis: 3.7;pituitary gland: 3.1;testis: 4.7;thyroid gland: 6.2" "Group enriched" "Detected in some" 8 "Astrocytes: 876.3;Excitatory neurons: 988.4;Inhibitory neurons: 1438.9" "Cancer enriched" "Detected in single" 19 "thyroid cancer: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "NTERA-2: 6.0;SCLC-21H: 2.5;SuSa: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016418 Approved Approved "Vesicles,Plasma membrane,Centriolar satellite" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane" "Centriolar satellite" "HPA016418: AB_2732416" "unprognostic (5.23e-2)" "unprognostic (2.33e-1)" "unprognostic (1.84e-1)" "unprognostic (3.32e-4)" "unprognostic (1.07e-1)" "unprognostic (9.64e-2)" "unprognostic (5.94e-3)" "unprognostic (1.88e-1)" "unprognostic (8.05e-2)" "unprognostic (1.89e-1)" "unprognostic (6.32e-3)" "unprognostic (3.51e-2)" "unprognostic (6.85e-10)" "unprognostic (3.15e-2)" "unprognostic (1.77e-1)" "unprognostic (1.97e-1)" "unprognostic (4.74e-3)" 0.3 0.8 1.7 0.0 2.0 0.1 0.0 0.2 1.4 0.1 0.0 0.4 0.0 0.0 3.7 0.0 0.1 0.1 1.7 1.0 1.8 0.0 0.1 0.1 0.0 1.0 2.4 0.0 0.1 0.0 3.1 0.0 1.6 0.2 0.1 0.5 0.0 0.6 0.0 0.0 0.1 0.0 1.1 0.0 0.1 4.7 2.3 0.0 6.2 0.0 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.0 0.2 1.4 1.0 1.8 1.0 2.4 1.6 1.1 2.3 0.7 0.1 6.4 1.1 876.3 0.0 0.1 0.2 1.5 0.0 11.2 0.0 0.0 10.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 123.9 0.1 0.1 4.2 0.0 0.0 988.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1438.9 0.0 4.1 0.0 0.0 98.9 16.1 0.3 0.0 34.7 0.2 0.5 0.0 32.2 17.2 0.4 0.0 4.1 0.0 0.3 0.0 0.1 0.0 1.8 0.0 0.4 0.2 3.8 1.5 0.0 0.1 0.0 0.5 6.2 0.0 0.3 MLC1 "KIAA0027, LVM, MLC, VL" ENSG00000100427 "Modulator of VRAC current 1" Q15049 22 50059391-50085426 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 262.7;choroid plexus: 145.6" "Cell type enriched" "Detected in some" 6 "Astrocytes: 115.6" "Cancer enriched" "Detected in some" 69 "glioma: 122.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 20.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HL-60: 228.2;NB-4: 219.8;THP-1: 401.5;U-266/70: 131.6;U-266/84: 120.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003040 Enhanced Supported Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol "HPA003040: AB_1079387" "unprognostic (2.68e-2)" "unprognostic (5.46e-6)" "unprognostic (5.41e-3)" "unprognostic (1.51e-1)" "unprognostic (1.47e-1)" "unprognostic (2.42e-3)" "unprognostic (9.54e-3)" "unprognostic (7.21e-2)" "unprognostic (2.24e-1)" "unprognostic (1.90e-1)" "unprognostic (1.31e-1)" "unprognostic (1.51e-3)" "unprognostic (8.39e-4)" "unprognostic (1.40e-1)" "unprognostic (1.55e-1)" "unprognostic (3.66e-2)" "unprognostic (2.92e-1)" 0.3 0.1 239.3 0.7 235.7 36.4 0.1 212.7 261.8 3.0 145.6 0.1 0.4 0.3 1.0 0.1 1.8 1.0 0.6 225.8 234.5 0.1 0.4 1.6 0.3 262.7 243.1 0.3 0.1 0.0 1.1 2.3 221.8 4.8 0.0 4.1 0.1 1.4 0.1 1.0 0.1 0.2 231.9 2.2 0.2 3.8 231.5 0.5 0.1 0.0 0.5 0.4 11.9 217.2 0.4 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 68.1 0.0 0.0 0.1 228.2 68.4 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 1.8 219.8 0.3 0.0 0.1 24.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 401.5 0.0 0.0 0.2 0.1 0.3 131.6 120.2 0.4 0.3 35.7 2.2 0.0 1.1 0.0 3.9 6.8 0.1 0.1 0.3 1.6 0.9 0.0 0.1 1.8 0.1 20.2 9.2 0.2 0.1 4.0 239.3 235.7 212.7 261.8 225.8 234.5 262.7 243.1 221.8 231.9 231.5 217.2 0.0 0.0 0.5 115.6 0.3 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.6 0.0 0.0 0.1 17.2 0.0 0.0 0.0 1.1 0.1 0.4 0.1 0.0 7.8 0.4 0.0 0.1 2.4 0.0 0.1 1.3 4.4 0.4 0.0 3.5 0.0 0.5 0.0 0.0 0.3 0.0 0.7 0.0 0.6 1.8 7.5 0.6 16.3 18.6 0.5 0.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.3 2.7 0.1 0.0 0.0 MMP25 "MMP20, MMPL1, MT6-MMP" ENSG00000008516 "Matrix metallopeptidase 25" Q9NPA2 16 3046062-3060726 "Enzymes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.1;lymphoid tissue: 81.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 6.7;Langerhans cells: 5.8;monocytes: 15.0" "Cancer enriched" "Detected in many" 5 "testis cancer: 7.1" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "basophil: 18.3;neutrophil: 20.3" "Lineage enriched" "Detected in single" 39 "granulocytes: 20.3" "Cell line enriched" "Detected in some" 15 "HMC-1: 102.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB025177, HPA055640" Uncertain Supported "Plasma membrane" "Secreted to blood" NA NA 120000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "CAB025177: , HPA055640: " "unprognostic (4.51e-3)" "unprognostic (9.28e-3)" "unprognostic (7.57e-2)" "unprognostic (2.95e-3)" "unprognostic (2.26e-1)" "prognostic favorable (1.09e-5)" "unprognostic (1.36e-1)" "unprognostic (7.39e-3)" "unprognostic (7.63e-3)" "unprognostic (2.29e-2)" "unprognostic (1.51e-1)" "unprognostic (2.53e-2)" "unprognostic (2.37e-3)" "unprognostic (1.17e-2)" "unprognostic (8.30e-2)" "unprognostic (4.01e-1)" "unprognostic (2.02e-1)" 5.8 0.4 0.5 15.1 0.4 33.1 1.4 0.3 1.6 0.7 0.6 1.7 1.1 0.5 0.1 1.3 6.2 1.1 2.4 0.3 0.3 1.4 2.9 14.4 2.6 0.6 0.5 0.4 1.2 0.2 0.8 1.0 0.6 1.0 1.4 0.0 1.2 0.1 0.5 0.7 3.5 0.9 0.3 81.8 1.9 0.4 0.7 1.4 1.2 3.5 1.9 2.2 0.9 0.3 0.0 0.0 1.2 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.7 0.1 0.0 6.7 0.5 0.0 0.0 0.0 0.0 0.2 102.2 0.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 5.7 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.2 0.3 7.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 1.1 0.1 18.3 0.2 4.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 20.3 0.5 0.0 0.4 0.2 0.0 0.5 0.4 0.3 1.6 0.3 0.3 0.6 0.5 0.6 0.3 0.7 0.3 1.0 3.2 6.7 0.0 0.7 0.4 0.4 0.2 0.0 0.8 2.0 1.3 1.0 0.0 0.8 1.8 0.0 0.0 1.8 0.2 0.0 0.4 0.0 1.2 1.2 1.0 0.0 2.7 1.6 0.6 0.2 0.6 1.1 3.8 1.3 0.2 0.0 0.3 0.1 0.0 1.9 0.2 0.0 3.5 5.8 0.0 0.0 3.3 0.0 1.0 15.0 0.3 3.1 1.5 0.5 1.3 0.0 0.7 0.8 0.4 1.2 0.2 0.1 0.0 0.0 0.7 0.9 0.1 0.2 0.6 0.3 0.0 4.0 0.1 0.3 0.3 MMP9 CLG4B ENSG00000100985 "Matrix metallopeptidase 9" P14780 20 46008908-46016561 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "bone marrow: 376.0;lymphoid tissue: 105.3" "Group enriched" "Detected in many" 5 "Hofbauer cells: 260.1;Langerhans cells: 606.0;Macrophages: 230.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebral cortex: 3.1;thalamus: 4.8" "Immune cell enriched" "Detected in some" 127 "neutrophil: 272.2" "Lineage enriched" "Detected in single" 341 "granulocytes: 272.2" "Cell line enriched" "Detected in some" 13 "NB-4: 360.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000348, HPA001238, HPA063909, CAB068199, CAB068200, CAB068201" Enhanced Approved Cytosol "Secreted to blood" NA NA 43300000 61000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB000348: , CAB068199: AB_2665675, CAB068200: AB_2665676, CAB068201: AB_2665677, HPA001238: AB_1079398, HPA063909: AB_2685150" "unprognostic (4.62e-2)" "unprognostic (1.64e-1)" "unprognostic (2.85e-2)" "prognostic favorable (2.55e-4)" "unprognostic (6.65e-3)" "unprognostic (2.82e-1)" "prognostic unfavorable (7.19e-4)" "unprognostic (1.54e-1)" "unprognostic (8.57e-2)" "unprognostic (3.21e-2)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (4.05e-5)" "unprognostic (4.65e-1)" "unprognostic (9.85e-3)" "unprognostic (2.48e-2)" "unprognostic (2.17e-3)" 19.5 0.6 0.5 61.9 0.8 376.0 8.2 0.4 3.1 2.9 0.8 5.7 11.6 1.0 0.0 2.2 2.2 3.0 3.2 0.3 0.9 2.6 3.8 21.1 103.2 0.8 0.5 0.8 1.6 0.1 1.1 2.0 0.7 1.9 3.4 0.6 3.6 0.4 0.7 3.2 12.4 1.9 0.4 105.3 11.3 1.3 4.8 17.0 2.1 0.9 36.5 12.0 1.1 0.2 0.2 0.4 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.3 0.3 28.8 0.0 0.3 0.4 0.0 1.4 0.0 0.3 0.5 0.1 0.0 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 4.0 0.0 360.6 0.8 0.0 0.2 0.4 0.3 0.1 0.0 0.0 0.6 0.6 0.0 0.6 0.0 3.7 0.3 1.2 0.3 10.3 10.9 0.1 0.3 0.3 0.2 0.2 0.1 0.8 0.2 0.0 0.7 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 272.2 0.0 0.3 0.0 0.0 0.5 0.5 0.8 0.4 3.1 0.3 0.9 0.8 0.5 0.7 0.4 4.8 0.2 0.7 0.0 5.5 0.0 3.9 34.3 0.1 61.5 0.0 3.8 0.5 2.0 0.4 1.5 0.9 0.0 8.4 1.5 2.0 0.0 0.0 0.8 0.9 0.0 0.1 7.2 0.0 0.0 0.1 1.8 2.4 2.5 0.0 0.1 1.3 0.2 0.0 0.0 260.1 3.3 0.2 0.5 0.0 1.3 606.0 0.3 0.0 230.6 56.9 0.0 2.3 1.2 0.0 0.0 0.0 1.8 0.0 0.0 0.9 0.1 0.0 0.3 6.9 5.3 0.0 0.2 45.5 6.7 11.2 0.2 28.1 1.9 3.4 0.3 0.0 0.1 MPST "MST, TST2, TUM1" ENSG00000128309 "Mercaptopyruvate sulfurtransferase" P25325 22 37019635-37029821 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 390.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 553.6;Hepatocytes: 578.6;Paneth cells: 621.4;Proximal enterocytes: 1322.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001240 Enhanced Approved Mitochondria,Cytosol NA NA 2900000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 45: Enterocytes - Digestion" Mitochondria Cytosol "HPA001240: AB_1079408" "unprognostic (7.18e-3)" "unprognostic (4.45e-1)" "unprognostic (1.80e-1)" "unprognostic (1.30e-3)" "unprognostic (1.73e-3)" "unprognostic (1.43e-1)" "unprognostic (7.07e-2)" "unprognostic (2.15e-1)" "unprognostic (2.22e-1)" "unprognostic (1.35e-1)" "unprognostic (2.25e-1)" "unprognostic (1.58e-1)" "unprognostic (3.15e-3)" "unprognostic (3.98e-2)" "unprognostic (3.51e-1)" "unprognostic (2.52e-1)" "prognostic favorable (5.89e-4)" 58.0 57.3 25.3 10.0 32.3 36.5 51.0 29.0 31.0 40.9 29.8 102.4 106.5 34.7 0.6 91.5 42.9 16.6 64.2 22.9 23.4 71.4 390.7 43.5 8.8 34.0 27.5 81.7 106.4 4.8 14.7 9.1 29.7 45.3 17.0 0.5 43.5 9.6 89.7 82.3 93.0 7.0 26.0 22.1 70.3 51.7 31.4 4.5 24.8 23.1 6.0 48.3 62.3 35.1 44.0 50.4 24.2 50.0 27.8 17.2 38.1 23.4 20.6 24.8 33.2 48.6 18.9 68.7 33.0 16.7 16.7 29.9 20.9 33.8 3.6 41.4 119.2 26.5 21.3 115.6 87.5 29.0 35.6 30.0 64.2 16.1 15.1 22.8 50.6 33.1 48.0 19.3 7.0 33.8 2.6 97.5 45.7 56.7 52.2 73.6 28.8 51.9 25.5 14.0 12.4 92.9 15.6 23.9 46.6 12.2 26.0 45.6 39.8 21.3 60.1 23.9 16.0 33.3 16.8 21.0 7.7 34.7 11.1 48.5 71.9 54.7 31.0 27.5 42.4 24.9 20.1 26.4 104.0 25.0 2.7 10.4 21.9 87.8 12.7 16.3 44.3 35.4 25.3 32.3 29.0 31.0 22.9 23.4 34.0 27.5 29.7 26.0 31.4 35.1 21.3 35.3 61.9 14.7 25.1 81.6 80.4 120.3 70.6 4.5 81.4 83.4 29.4 243.1 70.0 60.7 0.0 61.9 20.3 553.6 133.1 146.4 191.1 38.5 46.8 42.6 108.6 122.6 1.1 148.3 119.1 52.8 87.1 72.5 17.2 140.3 108.5 578.6 77.5 3.3 1.9 363.1 85.5 84.6 77.6 115.1 91.0 62.7 58.7 3.7 60.7 24.8 56.7 4.5 14.9 117.9 621.4 84.7 65.7 77.7 1322.1 469.8 13.4 2.8 46.0 34.4 36.0 101.3 11.5 133.7 152.9 50.1 26.6 57.7 397.5 110.6 MRC2 "CD280, CLEC13E, ENDO180, KIAA0709" ENSG00000011028 "Mannose receptor C type 2" Q9UBG0 17 62627670-62693597 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 93.9;Endometrial stromal cells: 65.2;Fibroblasts: 141.6;Late spermatids: 82.8;Leydig cells: 71.7;Peritubular cells: 102.3;Theca cells: 71.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 210.9;fHDF/TERT166: 164.9;HSkMC: 148.6;hTERT-RPE1: 150.6;U-138 MG: 216.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041991 Enhanced NA NA 36000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA041991: AB_10794166" "unprognostic (3.22e-1)" "unprognostic (2.19e-1)" "unprognostic (4.45e-2)" "unprognostic (2.59e-2)" "unprognostic (4.29e-2)" "unprognostic (2.67e-2)" "unprognostic (6.21e-2)" "unprognostic (1.80e-1)" "unprognostic (7.39e-2)" "prognostic unfavorable (1.68e-4)" "unprognostic (7.70e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (4.94e-7)" "unprognostic (5.25e-2)" "unprognostic (6.13e-2)" "unprognostic (3.00e-2)" "unprognostic (1.93e-2)" 24.5 8.6 4.8 13.7 7.9 5.3 16.2 5.6 5.3 39.3 22.5 12.3 6.6 31.3 9.6 21.2 26.3 32.4 45.2 4.3 5.1 18.1 2.8 35.0 4.5 9.3 9.1 45.8 7.5 1.2 17.4 9.6 8.9 25.7 3.2 0.7 9.0 20.8 12.2 28.8 10.9 21.3 9.9 16.3 9.0 16.2 6.0 4.5 7.0 6.5 2.0 17.9 28.2 11.2 0.1 35.1 23.3 29.7 64.1 115.4 3.1 210.9 138.8 34.3 40.8 2.1 0.4 0.0 15.2 164.9 15.1 17.8 4.0 19.0 8.8 26.7 5.4 17.6 27.2 0.0 97.2 22.9 0.2 148.6 9.5 29.6 3.4 150.6 15.4 10.6 9.3 0.0 47.8 6.3 6.6 70.6 4.9 0.0 2.4 22.3 15.4 0.2 3.2 0.4 2.9 52.2 14.1 0.4 0.3 14.3 0.6 97.1 68.5 216.6 83.9 36.2 43.6 0.2 0.0 0.0 66.8 22.6 34.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 4.8 7.9 5.6 5.3 4.3 5.1 9.3 9.1 8.9 9.9 6.0 11.2 8.6 3.2 35.9 5.9 0.4 11.3 5.8 20.7 25.0 11.1 1.6 11.4 4.4 0.0 2.3 1.8 0.0 0.7 0.6 0.1 0.0 0.3 93.9 22.6 65.2 5.2 0.0 28.4 3.3 0.2 2.7 141.6 2.0 2.9 2.5 13.8 5.3 0.0 6.8 0.0 0.9 0.1 0.0 9.2 11.1 82.8 71.7 7.0 5.4 57.1 0.6 0.8 1.0 3.5 0.9 0.6 0.0 102.3 0.3 2.1 0.0 0.0 1.4 0.6 0.0 31.4 23.3 11.7 9.3 34.6 7.7 1.9 2.7 71.0 0.2 1.4 MREG "DSU, FLJ10116, WDT2" ENSG00000118242 Melanoregulin Q8N565 2 215942584-216034096 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 46.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 60.5;Glandular and luminal cells: 34.1;Rod photoreceptor cells: 40.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 82.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068583 Approved Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 44: Endometrium - Transcription" Vesicles "HPA068583: AB_2686009" "unprognostic (4.53e-2)" "unprognostic (1.12e-1)" "unprognostic (3.05e-1)" "unprognostic (1.20e-2)" "unprognostic (3.24e-1)" "unprognostic (1.13e-2)" "unprognostic (3.70e-1)" "unprognostic (7.37e-2)" "unprognostic (2.39e-1)" "unprognostic (5.85e-3)" "unprognostic (8.11e-3)" "unprognostic (8.93e-2)" "unprognostic (6.38e-3)" "unprognostic (6.62e-3)" "unprognostic (6.92e-2)" "prognostic favorable (4.20e-4)" "unprognostic (9.99e-2)" 5.9 8.2 3.9 5.4 8.9 5.9 21.4 17.9 5.6 6.7 6.2 5.6 6.4 3.4 5.0 29.8 5.8 2.8 0.7 4.6 4.5 5.4 17.8 10.3 10.8 5.6 4.7 2.5 2.2 7.3 7.6 7.7 5.9 2.4 5.8 46.9 4.9 6.1 2.7 20.2 5.5 1.8 3.3 4.4 6.8 1.1 6.5 9.9 6.6 0.9 15.1 5.5 14.3 5.0 20.9 5.1 5.9 3.5 3.9 2.1 13.1 7.0 5.6 4.6 8.9 24.3 15.5 6.7 6.0 4.3 11.5 13.0 17.9 26.5 10.1 14.1 15.1 10.6 5.6 43.5 2.3 6.0 3.9 3.9 11.2 5.3 7.4 4.6 4.0 15.2 5.3 17.8 2.9 82.8 17.0 5.7 23.3 12.4 4.8 9.8 13.9 10.7 12.3 29.3 16.4 8.6 4.4 36.4 40.3 13.7 20.2 2.8 0.5 9.8 2.5 5.0 10.7 23.0 15.3 17.5 6.0 22.2 7.5 1.6 0.1 0.2 0.7 0.1 1.2 1.1 0.6 1.1 0.1 0.6 0.3 0.5 0.8 0.8 0.2 2.1 1.0 0.1 3.9 8.9 17.9 5.6 4.6 4.5 5.6 4.7 5.9 3.3 6.5 5.0 0.6 3.2 13.4 7.8 4.3 2.7 12.1 0.6 9.6 14.4 24.1 12.1 0.8 2.8 9.2 7.3 60.5 21.7 8.5 3.8 3.9 3.2 0.3 14.0 1.9 1.1 1.8 2.1 21.1 2.5 4.7 1.8 5.6 34.1 1.3 0.6 1.4 8.3 13.4 1.7 21.4 1.8 2.0 0.8 3.0 0.0 2.5 4.0 5.4 6.5 21.3 7.6 2.1 8.5 12.8 7.5 4.6 7.5 7.0 7.0 3.1 1.1 3.0 40.1 6.6 1.2 1.2 1.1 4.6 28.7 1.6 25.9 4.0 1.0 2.9 22.6 MROH2A HEATR7B1 ENSG00000185038 "Maestro heat like repeat family member 2A" A6NES4 2 233775679-233833423 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 1.7;thyroid gland: 1.6" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 3.4;Early spermatids: 1.3;Hepatocytes: 1.0;Late spermatids: 1.7;Spermatocytes: 1.5" "Cancer enhanced" "Detected in some" "urothelial cancer: 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "RT4: 6.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA052107 Uncertain Uncertain Cytosol NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 15: RT4 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA052107: AB_2681729" "unprognostic (7.00e-2)" "unprognostic (3.37e-3)" "unprognostic (4.77e-1)" "unprognostic (1.65e-2)" "unprognostic (4.03e-1)" "unprognostic (1.71e-1)" "unprognostic (1.87e-1)" "unprognostic (4.41e-2)" "unprognostic (2.69e-1)" "unprognostic (1.67e-1)" "unprognostic (4.32e-2)" "unprognostic (5.05e-2)" "unprognostic (4.06e-9)" "unprognostic (5.65e-2)" "unprognostic (3.90e-2)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.7 0.1 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.4 3.4 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 1.5 0.6 0.6 0.1 0.0 0.0 0.0 0.0 0.3 MRS2 MRS2L ENSG00000124532 "Magnesium transporter MRS2" Q9HD23 6 24402908-24426194 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017642 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA017642: AB_2669628" "unprognostic (2.12e-3)" "unprognostic (1.22e-1)" "unprognostic (5.64e-3)" "prognostic unfavorable (5.32e-4)" "unprognostic (7.23e-2)" "unprognostic (8.57e-2)" "unprognostic (1.82e-1)" "unprognostic (1.20e-1)" "unprognostic (3.89e-3)" "prognostic favorable (5.14e-11)" "unprognostic (8.75e-2)" "unprognostic (2.94e-2)" "unprognostic (8.32e-2)" "unprognostic (2.53e-1)" "unprognostic (8.56e-2)" "prognostic unfavorable (8.03e-4)" "unprognostic (1.55e-3)" 14.6 17.0 10.7 12.0 11.8 6.7 14.3 17.1 13.7 10.9 15.4 14.1 15.4 10.3 14.1 14.1 10.2 9.3 30.7 11.2 12.2 24.2 20.5 10.9 14.9 10.8 11.7 12.3 18.8 22.5 13.4 16.4 11.2 12.8 15.4 30.1 15.9 13.4 52.9 12.3 12.1 10.7 10.9 11.4 15.7 6.3 12.2 8.7 16.3 49.4 14.8 13.2 11.5 11.4 36.7 21.0 24.7 46.3 15.9 14.4 54.8 16.6 19.3 20.5 18.5 80.9 16.9 21.2 67.3 14.6 32.2 21.8 25.6 31.6 22.0 26.8 44.9 33.6 16.4 93.7 23.0 38.7 30.0 22.8 24.7 20.9 16.7 23.8 22.2 27.2 49.5 0.0 22.6 28.9 37.1 35.3 64.6 20.6 18.9 0.2 4.3 48.4 90.5 37.1 39.3 23.7 28.1 84.9 46.5 72.0 43.3 26.3 9.6 9.1 13.8 18.9 30.8 37.4 68.1 29.4 11.3 45.4 38.3 3.4 16.8 7.3 11.6 20.2 14.9 14.4 12.4 12.5 24.8 11.9 13.4 12.6 1.9 15.3 18.8 14.8 11.5 12.1 10.7 11.8 17.1 13.7 11.2 12.2 10.8 11.7 11.2 10.9 12.2 11.4 10.5 35.3 20.0 18.6 18.0 7.1 13.6 18.8 16.5 33.5 15.7 10.4 55.6 20.0 16.4 20.2 39.6 46.5 23.3 13.6 52.8 22.6 0.6 15.7 11.5 11.3 9.6 17.1 33.7 19.1 24.6 14.8 13.3 12.9 12.0 23.3 11.4 14.4 21.9 50.5 35.6 15.4 22.4 15.8 10.0 0.7 12.2 14.8 7.2 9.4 19.6 21.8 16.5 15.1 16.5 15.9 14.9 16.6 19.7 14.7 20.0 40.7 14.4 43.6 19.7 9.2 12.9 5.4 11.6 22.7 11.2 25.3 13.1 27.2 22.3 15.7 MS4A7 "CD20L4, CFFM4, MS4A8" ENSG00000166927 "Membrane spanning 4-domains A7" Q9GZW8 11 60378485-60395951 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 196.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 311.4;Kupffer cells: 1060.3;Macrophages: 567.5;monocytes: 184.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "intermediate monocyte: 747.4;non-classical monocyte: 1486.0" "Lineage enriched" "Detected in many" 12 "monocytes: 1486.0" "Cell line enriched" "Detected in some" 25 "THP-1: 114.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA017418, CAB026387" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB026387: , HPA017418: AB_1854137" "unprognostic (1.43e-1)" "unprognostic (2.60e-3)" "unprognostic (3.24e-2)" "unprognostic (9.67e-2)" "unprognostic (2.04e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-1)" "unprognostic (9.51e-2)" "unprognostic (3.02e-2)" "unprognostic (4.85e-2)" "unprognostic (5.79e-2)" "unprognostic (1.90e-1)" "unprognostic (1.43e-2)" "unprognostic (4.59e-2)" "unprognostic (3.90e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" 46.9 37.6 6.3 50.9 5.0 10.7 30.7 4.5 13.7 18.2 13.9 21.4 17.6 7.6 4.1 12.7 6.6 46.8 9.9 4.2 8.7 8.0 66.5 75.7 23.2 12.8 10.4 6.0 6.0 9.0 4.7 43.9 11.4 4.9 23.3 1.2 6.7 9.0 1.9 2.3 25.1 15.9 7.4 196.6 14.8 4.7 17.1 18.2 7.3 4.1 18.6 41.2 3.9 18.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 2.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.5 0.1 0.0 0.1 1.1 0.1 0.1 0.0 2.8 0.0 0.1 0.1 0.8 0.5 0.0 0.0 114.2 0.0 0.1 0.1 0.1 0.1 0.2 0.2 3.0 0.0 3.1 0.0 8.3 188.0 2.5 0.8 747.4 1.1 22.3 0.6 0.5 120.9 19.7 0.8 0.4 9.3 0.8 1486.0 3.2 0.9 137.8 6.3 5.0 4.5 13.7 4.2 8.7 12.8 10.4 11.4 7.4 17.1 18.3 5.0 12.8 31.4 0.0 30.6 2.7 0.8 0.0 0.6 3.6 14.7 9.9 2.1 0.0 3.7 9.2 0.0 1.0 1.4 0.3 0.0 0.0 2.4 0.1 0.0 12.2 0.0 10.1 0.1 0.2 1.7 3.9 1.5 0.1 13.9 0.1 11.0 4.7 311.4 0.0 0.2 0.0 0.0 1060.3 93.4 1.2 1.2 567.5 1.8 59.0 184.8 0.4 4.1 0.0 0.3 0.1 1.1 0.0 1.8 1.1 0.0 0.7 7.3 0.5 19.7 2.2 1.2 0.0 0.4 0.9 1.8 1.9 5.3 0.3 0.1 1.0 MSRB2 "CBS-1, CBS1, CGI-131, MSRB, PILB" ENSG00000148450 "Methionine sulfoxide reductase B2" Q9Y3D2 10 23095579-23122013 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 269.1;Proximal tubular cells: 463.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027933 Enhanced "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA027933: AB_10601867" "unprognostic (4.89e-2)" "unprognostic (2.76e-2)" "unprognostic (7.14e-3)" "unprognostic (3.47e-3)" "unprognostic (4.51e-1)" "unprognostic (9.26e-3)" "unprognostic (1.62e-1)" "unprognostic (1.09e-1)" "unprognostic (1.80e-1)" "unprognostic (6.07e-3)" "unprognostic (3.47e-2)" "unprognostic (1.08e-2)" "unprognostic (2.03e-1)" "unprognostic (1.82e-2)" "unprognostic (6.74e-2)" "unprognostic (1.11e-1)" "unprognostic (2.01e-1)" 16.2 17.3 29.0 6.6 30.8 7.7 11.0 29.5 40.5 13.2 26.8 22.7 9.4 15.8 16.8 10.8 17.6 7.7 61.6 29.5 32.2 19.0 31.0 9.8 3.9 30.4 30.9 11.9 5.4 23.1 14.4 8.2 30.5 14.3 11.4 13.1 9.1 19.5 42.2 5.5 11.9 16.3 29.1 9.3 11.4 3.9 30.8 8.4 14.1 51.7 4.1 17.1 11.0 29.4 7.3 10.4 19.0 11.6 19.3 17.3 5.7 11.5 6.4 7.2 8.3 7.2 15.5 5.9 10.0 24.6 10.9 4.6 6.3 8.6 5.9 40.3 7.0 4.3 17.7 4.1 27.2 0.9 5.0 22.2 14.3 8.4 2.0 15.7 10.4 11.5 5.9 10.3 16.0 21.9 7.0 5.5 10.5 41.4 6.0 8.0 10.9 1.5 9.1 2.8 3.8 26.1 14.2 12.4 23.9 15.9 8.4 17.1 7.7 6.2 5.8 14.0 6.9 13.3 4.4 0.2 8.8 12.7 5.3 0.9 1.4 2.3 0.3 1.1 0.3 0.2 0.3 0.2 0.8 0.0 0.6 0.4 3.4 0.2 0.8 1.6 0.4 0.2 29.0 30.8 29.5 40.5 29.5 32.2 30.4 30.9 30.5 29.1 30.8 29.4 29.0 0.0 16.4 27.1 11.4 18.2 52.1 33.1 59.2 68.2 69.6 79.1 269.1 80.1 21.1 90.1 22.9 116.1 10.6 86.7 176.1 130.4 1.4 49.3 71.6 34.4 55.7 30.7 9.5 63.4 61.2 70.7 23.4 46.5 29.2 114.0 42.1 195.4 109.6 112.7 16.9 54.8 26.4 70.5 25.1 4.4 49.7 54.2 72.9 11.2 29.7 126.6 7.2 14.6 26.1 90.3 79.6 62.4 24.7 34.9 80.8 463.9 24.3 57.5 59.2 52.6 71.6 4.4 7.7 66.7 17.5 69.6 13.5 60.9 71.0 54.3 MTARC1 "FLJ22390, MARC1, MOSC1" ENSG00000186205 "Mitochondrial amidoxime reducing component 1" Q5VT66 1 220786913-220819659 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 192.3;breast: 86.2;liver: 84.5" "Group enriched" "Detected in some" 6 "Cytotrophoblasts: 109.8;Extravillous trophoblasts: 47.9;Syncytiotrophoblasts: 75.1" "Cancer enhanced" "Detected in many" "prostate cancer: 14.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "basophil: 30.2;classical monocyte: 33.6;eosinophil: 12.3;neutrophil: 42.8" "Group enriched" "Detected in many" 31 "granulocytes: 42.8;monocytes: 33.6" "Cell line enhanced" "Detected in many" "BEWO: 126.5;HeLa: 56.2;Hep G2: 67.6;NTERA-2: 57.8;OE19: 49.4" HPA028702 Approved Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA028702: AB_10601135" "unprognostic (3.15e-2)" "unprognostic (1.27e-1)" "unprognostic (2.16e-2)" "unprognostic (5.04e-2)" "unprognostic (2.90e-1)" "unprognostic (2.31e-1)" "unprognostic (3.71e-3)" "unprognostic (1.39e-1)" "unprognostic (7.51e-2)" "unprognostic (7.71e-3)" "unprognostic (3.71e-1)" "unprognostic (4.30e-1)" "prognostic unfavorable (4.51e-4)" "unprognostic (3.85e-1)" "unprognostic (1.21e-1)" "unprognostic (1.24e-1)" "unprognostic (1.50e-1)" 192.3 7.4 9.4 6.8 10.5 17.9 86.2 9.8 13.2 7.9 7.9 18.9 7.6 2.8 14.0 7.6 6.2 4.1 8.4 10.0 11.7 10.2 84.5 9.3 2.8 10.1 11.8 5.5 9.6 5.4 7.0 16.0 9.6 36.2 17.3 5.7 27.2 13.5 11.0 3.6 9.7 4.0 9.1 10.2 9.3 1.4 14.3 1.6 53.5 9.2 2.1 8.8 5.0 8.5 15.0 7.8 5.9 0.2 1.3 0.3 126.5 1.4 1.2 0.8 1.5 45.4 1.0 0.1 5.3 1.6 0.1 0.1 28.3 2.9 2.1 0.2 25.7 0.1 56.2 67.6 2.7 0.3 0.5 4.5 1.3 0.2 0.0 0.2 1.1 0.1 4.3 0.3 1.1 14.7 0.1 31.9 57.8 49.4 23.8 0.1 0.0 0.3 7.1 17.4 16.4 36.1 8.1 11.4 0.2 16.4 38.5 34.7 0.4 0.1 12.6 0.1 0.1 0.2 0.1 0.1 0.2 0.0 1.1 30.2 33.6 12.3 0.1 2.5 0.0 0.4 0.0 0.0 1.2 0.2 0.1 0.0 42.8 0.0 1.3 0.3 0.0 9.2 9.4 10.5 9.8 13.2 10.0 11.7 10.1 11.8 9.6 9.1 14.3 8.5 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 109.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 47.9 0.7 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 75.1 0.0 0.0 0.0 0.0 MTARC2 "FLJ20605, MARC2, MOSC2" ENSG00000117791 "Mitochondrial amidoxime reducing component 2" Q969Z3 1 220748225-220784815 "Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 132.5;liver: 223.6" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 29.0" "Cancer enhanced" "Detected in all" "liver cancer: 35.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 14.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 14.1" "Cell line enhanced" "Detected in many" "T-47d: 36.0;TIME: 33.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015085, HPA017572" Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 24: Non-specific - Transcription regulation" "HPA015085: AB_1848780, HPA017572: AB_1848778" "unprognostic (8.17e-2)" "unprognostic (1.92e-2)" "unprognostic (1.80e-1)" "unprognostic (1.66e-2)" "unprognostic (1.16e-1)" "unprognostic (8.20e-2)" "prognostic favorable (1.40e-10)" "unprognostic (4.78e-2)" "unprognostic (2.67e-2)" "unprognostic (2.78e-1)" "unprognostic (1.90e-1)" "unprognostic (2.05e-2)" "prognostic favorable (3.09e-4)" "unprognostic (1.45e-1)" "unprognostic (1.81e-1)" "unprognostic (2.39e-2)" "unprognostic (6.23e-2)" 30.4 17.9 10.3 6.2 11.8 0.6 16.5 7.8 15.4 11.6 54.5 17.9 59.1 6.7 15.6 9.7 10.8 21.6 25.0 11.2 10.1 132.5 223.6 31.2 7.4 7.9 11.7 21.9 29.9 125.0 9.5 12.7 8.3 20.2 20.5 3.0 36.3 12.5 34.5 4.7 58.2 9.5 8.2 11.6 27.9 11.0 11.9 3.1 42.1 21.4 8.2 12.5 10.4 9.9 9.5 7.8 4.1 5.4 10.1 4.6 3.2 6.7 11.7 8.0 8.1 5.3 11.9 0.0 4.6 6.5 4.3 1.3 0.0 9.4 7.5 0.0 15.7 0.0 16.5 11.0 9.3 4.5 0.0 8.0 14.1 3.0 0.0 12.1 22.2 0.0 6.3 0.1 5.1 2.3 0.0 15.7 6.6 3.2 7.8 0.0 13.0 0.2 28.2 10.3 2.3 6.1 10.6 0.1 15.2 4.5 36.0 5.6 33.9 0.0 4.8 10.6 12.0 2.0 0.1 0.0 1.7 0.0 0.1 14.1 0.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 10.3 11.8 7.8 15.4 11.2 10.1 7.9 11.7 8.3 8.2 11.9 9.9 7.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.7 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 MTFR1L FAM54B ENSG00000117640 "Mitochondrial fission regulator 1 like" Q9H019 1 25818640-25832942 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 161.1;Early spermatids: 216.1;Late spermatids: 590.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027124, HPA027130" Approved Approved "Cell Junctions,Mitochondria" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "Cell Junctions" "HPA027124: AB_10600211, HPA027130: AB_10611251" "unprognostic (9.90e-2)" "unprognostic (6.86e-3)" "unprognostic (9.29e-2)" "prognostic favorable (6.81e-4)" "unprognostic (1.16e-1)" "unprognostic (1.58e-2)" "unprognostic (1.43e-1)" "unprognostic (4.52e-3)" "unprognostic (2.12e-1)" "unprognostic (2.24e-1)" "unprognostic (9.89e-3)" "unprognostic (5.33e-2)" "prognostic favorable (5.89e-12)" "unprognostic (1.41e-1)" "unprognostic (1.22e-1)" "unprognostic (2.69e-1)" "unprognostic (1.33e-1)" 39.0 138.0 79.6 22.2 82.8 17.8 37.4 80.0 88.4 51.0 84.6 74.1 46.8 51.0 57.8 39.4 44.9 32.7 169.1 81.7 81.3 71.7 91.3 32.4 25.8 80.2 83.8 68.4 46.0 106.0 51.6 40.7 79.6 55.8 37.3 62.1 43.3 70.1 221.8 35.6 46.9 50.0 78.6 44.2 56.6 82.5 83.2 24.7 48.1 239.7 26.3 58.3 40.5 78.5 19.5 26.7 53.2 53.6 67.6 63.8 22.2 44.7 63.7 45.2 49.9 8.7 39.7 6.6 38.9 80.1 40.0 17.4 44.1 38.6 44.8 43.9 39.8 55.6 44.3 35.9 64.6 45.5 52.9 65.3 36.4 48.3 36.1 67.0 37.9 27.0 34.7 29.2 66.1 21.6 26.3 33.6 29.4 26.0 39.4 26.0 47.4 19.8 47.1 18.3 53.6 48.5 33.6 32.4 67.8 35.8 26.7 43.1 38.6 36.7 28.9 86.6 28.5 30.5 19.3 23.2 63.6 62.5 41.2 71.7 50.5 111.7 25.7 50.8 15.6 28.1 24.1 22.9 55.0 28.8 25.4 23.1 13.6 27.6 58.3 22.7 27.3 51.1 79.6 82.8 80.0 88.4 81.7 81.3 80.2 83.8 79.6 78.6 83.2 78.5 18.7 16.0 24.5 24.2 14.1 13.5 20.8 38.6 25.0 0.0 21.6 23.6 161.1 25.8 21.7 22.0 0.0 55.9 14.8 15.7 103.7 32.4 216.1 11.3 16.7 17.1 15.6 12.4 18.2 33.5 36.7 28.4 21.4 10.6 36.1 21.9 21.4 35.5 34.9 0.0 24.1 14.9 34.6 15.1 17.3 590.4 34.2 25.6 44.4 6.5 43.5 0.0 12.3 12.5 15.2 27.7 15.0 39.1 15.4 16.2 39.3 70.6 10.5 0.0 26.3 23.3 31.3 144.7 49.9 15.4 12.9 59.4 13.1 29.8 18.0 16.5 MTMR10 FLJ20313 ENSG00000166912 "Myotubularin related protein 10" Q9NXD2 15 30938941-30991628 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 86.2;Oligodendrocytes: 149.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006081 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nuclear bodies" Cytosol "HPA006081: AB_2667508" "unprognostic (1.60e-1)" "unprognostic (6.09e-2)" "unprognostic (1.21e-1)" "unprognostic (1.36e-1)" "unprognostic (2.18e-1)" "unprognostic (7.36e-2)" "unprognostic (4.43e-2)" "unprognostic (7.26e-2)" "unprognostic (1.24e-1)" "unprognostic (3.31e-2)" "unprognostic (6.43e-2)" "unprognostic (2.54e-1)" "prognostic favorable (7.77e-12)" "unprognostic (9.92e-2)" "unprognostic (1.15e-1)" "unprognostic (1.79e-1)" "unprognostic (1.01e-1)" 18.6 9.5 29.3 10.7 46.9 18.7 10.3 49.4 33.3 11.2 24.8 9.9 12.8 9.4 9.4 20.9 7.5 9.6 12.7 28.0 36.3 30.6 24.2 13.6 12.0 57.6 48.5 11.5 12.4 21.3 1.9 25.9 56.5 11.0 10.3 12.1 14.9 11.4 29.4 11.2 11.6 10.0 45.3 15.1 13.0 8.5 40.8 16.7 14.2 24.0 10.6 10.1 5.4 63.3 8.1 9.0 8.2 5.2 17.7 9.6 7.2 11.9 23.9 9.4 9.4 5.9 3.5 3.9 15.5 15.5 9.1 11.5 6.5 7.0 8.9 12.5 2.1 5.5 6.2 10.4 10.3 8.9 12.2 13.2 5.4 6.1 6.7 10.8 23.7 10.9 4.9 9.2 8.9 2.3 9.3 5.6 4.7 9.7 4.3 6.7 6.7 19.5 35.6 12.7 3.0 7.8 5.4 6.3 2.4 10.4 4.2 16.4 10.9 10.6 8.0 5.6 6.8 9.4 7.8 9.0 6.7 4.7 13.4 3.7 3.2 3.1 0.7 4.0 0.8 1.9 0.8 0.6 3.1 2.8 1.2 1.2 13.5 1.4 7.4 3.7 1.2 1.7 29.3 46.9 49.4 33.3 28.0 36.3 57.6 48.5 56.5 45.3 40.8 63.3 15.8 25.6 15.2 86.2 11.3 8.9 4.3 3.3 8.0 0.0 6.7 4.6 24.1 10.0 7.0 33.1 0.0 19.3 12.9 12.7 1.9 3.4 13.6 10.1 9.6 16.8 6.0 5.2 15.4 3.8 3.1 8.6 13.3 19.7 17.1 9.4 11.4 33.9 11.8 0.0 13.6 7.7 2.0 24.9 16.2 24.9 10.5 19.0 8.8 55.3 13.8 0.0 3.1 25.6 149.3 5.6 9.2 7.5 8.0 6.7 14.4 18.6 4.7 0.0 0.0 10.6 8.9 11.1 8.9 33.6 11.1 38.4 6.8 6.7 8.2 8.7 MTSS1 "KIAA0429, MIM, MIMA, MIMB" ENSG00000170873 "MTSS I-BAR domain containing 1" O43312 8 124550784-124728473 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 208.2;Oligodendrocyte precursor cells: 360.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 168.3" "Group enriched" "Detected in all" 5 "B-cells: 50.3;monocytes: 168.3" "Cell line enhanced" "Detected in many" "ASC diff: 81.4;HDLM-2: 98.7;HEL: 337.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019613, HPA064003, HPA075540" Approved Supported Approved "Plasma membrane,Cytosol" NA NA 140000 "Cluster 51: Monocytes - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "HPA019613: , HPA064003: , HPA075540: AB_2686756" "unprognostic (1.70e-1)" "unprognostic (4.13e-2)" "unprognostic (9.50e-2)" "unprognostic (1.38e-1)" "unprognostic (3.87e-2)" "unprognostic (7.02e-2)" "unprognostic (4.24e-2)" "unprognostic (1.26e-2)" "unprognostic (2.18e-1)" "unprognostic (2.50e-1)" "unprognostic (8.12e-2)" "unprognostic (1.48e-1)" "prognostic favorable (2.11e-7)" "unprognostic (6.74e-2)" "unprognostic (1.04e-1)" "unprognostic (2.41e-1)" "unprognostic (8.92e-3)" 24.5 36.2 16.8 13.2 23.2 12.5 14.0 46.1 23.4 12.5 22.3 11.0 6.4 8.4 9.9 45.2 12.5 9.2 17.1 16.3 27.7 24.2 72.9 16.5 16.0 27.5 20.6 10.4 28.5 3.7 11.0 35.7 25.3 10.1 9.1 15.0 13.9 6.3 32.3 30.8 7.9 9.6 20.5 34.5 12.0 22.3 26.4 18.4 6.0 24.4 17.2 15.5 24.3 39.5 3.6 1.1 51.6 1.0 81.4 41.7 0.1 2.1 14.2 1.1 0.5 4.8 0.4 1.6 4.9 0.2 0.4 0.8 0.4 29.2 1.1 98.7 1.2 337.8 0.9 27.0 18.4 0.0 34.5 66.4 65.4 15.9 41.0 2.1 31.5 0.3 0.5 0.3 5.6 2.7 0.8 4.0 1.8 54.8 0.4 0.4 0.1 0.5 11.6 11.3 36.3 2.8 7.9 6.3 26.6 2.5 1.3 1.1 16.7 2.7 1.0 0.2 0.7 0.5 0.3 5.4 29.1 0.4 10.7 3.1 13.1 0.1 22.7 88.1 2.6 44.9 4.8 8.7 11.8 50.3 2.2 6.8 2.2 2.2 168.3 0.2 0.5 29.2 16.8 23.2 46.1 23.4 16.3 27.7 27.5 20.6 25.3 20.5 26.4 39.5 33.0 0.0 26.9 15.7 92.0 35.8 81.4 41.2 9.6 0.0 8.0 19.9 34.9 22.8 30.9 66.2 0.0 36.0 51.4 10.7 21.5 17.6 54.2 25.5 0.9 32.2 44.2 17.2 40.4 5.2 2.3 30.5 26.5 9.7 46.3 0.9 70.3 78.1 74.2 0.0 208.2 17.1 61.1 167.1 116.2 62.1 3.7 96.7 26.6 114.3 90.2 0.0 78.2 360.4 178.4 32.6 15.9 4.5 12.6 71.9 1.2 19.9 42.0 0.0 39.5 25.2 17.3 2.5 10.7 86.1 63.4 94.4 22.7 1.8 15.8 59.2 MXRA5 DKFZp564I1922 ENSG00000101825 "Matrix remodeling associated 5" Q9NR99 X 3308565-3346652 "Cancer-related genes, Disease related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 35.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 38.5;Collecting duct cells: 31.3;Exocrine glandular cells: 60.7;Fibroblasts: 56.0;Pancreatic endocrine cells: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 31.4;BJ hTERT+: 125.8;fHDF/TERT166: 59.8;HaCaT: 52.4;HSkMC: 24.7" "Low region specificity" "Detected in all" "HPA000508, HPA076518" Uncertain Uncertain Mitochondria "Secreted to extracellular matrix" NA NA 2600000 "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA000508: AB_2147995, HPA076518: " "unprognostic (7.51e-2)" "unprognostic (6.45e-2)" "unprognostic (8.00e-2)" "unprognostic (2.51e-2)" "prognostic unfavorable (1.81e-4)" "unprognostic (7.05e-2)" "unprognostic (7.25e-2)" "unprognostic (1.35e-2)" "unprognostic (1.13e-1)" "unprognostic (2.53e-2)" "unprognostic (6.32e-3)" "unprognostic (1.38e-1)" "unprognostic (1.65e-2)" "unprognostic (1.58e-1)" "unprognostic (1.90e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (8.94e-4)" 12.0 10.3 0.2 9.4 0.3 0.0 13.5 0.0 0.4 35.0 0.0 7.5 4.4 6.8 2.7 9.4 3.0 8.0 11.1 0.2 0.1 5.3 4.5 5.3 1.6 0.3 0.3 2.9 16.1 1.7 0.9 5.8 0.2 7.3 10.4 0.0 6.1 10.4 1.5 29.6 4.6 15.9 0.5 3.6 10.3 0.1 1.2 5.7 9.8 5.1 3.7 19.9 7.2 0.1 0.0 0.0 0.8 0.0 0.2 31.4 0.0 19.6 125.8 0.2 0.2 0.0 0.6 0.0 1.7 59.8 0.2 52.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 24.7 5.9 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 2.0 1.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.4 0.2 0.1 0.3 0.3 0.2 0.5 1.2 0.1 10.3 0.0 0.0 0.0 0.0 38.5 7.1 10.5 20.5 0.0 2.0 4.6 1.9 0.0 3.7 31.3 0.0 0.1 0.3 0.9 0.0 2.2 0.0 1.0 8.4 4.6 0.0 0.0 0.7 60.7 0.7 56.0 0.0 1.6 0.0 0.0 10.8 0.1 0.3 0.0 1.1 0.0 0.0 0.3 16.9 0.0 0.0 0.3 17.8 4.7 0.6 0.0 0.0 0.5 0.2 42.8 0.0 1.5 0.1 0.2 0.1 0.1 1.0 0.2 0.0 7.3 9.8 0.0 0.0 5.5 21.7 0.3 1.1 0.9 0.4 2.0 MXRA8 DKFZp586E2023 ENSG00000162576 "Matrix remodeling associated 8" Q9BRK3 1 1352689-1361777 "Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 149.5;Extravillous trophoblasts: 259.9;Fibroblasts: 183.3;Leydig cells: 176.1;Peritubular cells: 183.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "naive CD8 T-cell: 6.4" "Lineage enriched" "Detected in single" 64 "T-cells: 6.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 46.0;BJ: 143.6;BJ hTERT+: 66.9;fHDF/TERT166: 71.9;HSkMC: 54.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053958, HPA055780" Uncertain Approved Nucleoli NA NA 760000 "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoli "HPA053958: AB_2682322, HPA055780: AB_2682918" "unprognostic (1.39e-1)" "unprognostic (2.85e-1)" "unprognostic (7.31e-3)" "unprognostic (1.26e-2)" "unprognostic (1.94e-3)" "unprognostic (2.61e-1)" "unprognostic (6.75e-2)" "unprognostic (2.03e-1)" "unprognostic (4.22e-2)" "unprognostic (5.38e-2)" "unprognostic (2.97e-2)" "unprognostic (7.13e-2)" "prognostic unfavorable (3.43e-6)" "prognostic unfavorable (9.93e-4)" "unprognostic (1.55e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (9.87e-4)" 103.6 11.7 2.9 8.2 2.5 0.6 70.0 1.1 2.9 100.4 1.7 58.2 6.3 117.2 2.6 17.6 57.4 19.4 42.8 4.0 2.4 26.4 7.4 53.9 2.5 5.9 4.5 81.9 8.7 1.1 21.7 11.6 2.6 39.0 1.7 0.8 32.4 11.4 16.6 41.6 29.5 6.4 2.3 26.4 28.9 14.7 3.2 0.6 46.6 5.0 0.8 52.8 59.3 3.0 4.1 0.8 1.2 1.0 16.5 46.0 42.3 143.6 66.9 16.6 19.9 8.0 3.3 1.7 0.6 71.9 0.1 3.0 1.0 0.0 3.2 3.2 1.3 1.2 3.1 12.8 43.4 0.2 1.6 54.8 0.0 6.2 0.0 32.4 0.0 0.9 17.3 1.4 21.5 0.4 0.4 0.5 14.0 0.3 4.7 0.6 0.3 0.4 0.0 0.7 3.2 8.9 0.5 1.4 0.1 10.4 11.1 0.7 1.3 0.7 23.1 21.8 0.6 3.3 0.3 0.2 5.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 6.4 0.0 0.0 0.0 0.0 0.0 0.2 2.9 2.5 1.1 2.9 4.0 2.4 5.9 4.5 2.6 2.3 3.2 3.0 22.2 3.2 0.0 7.5 0.5 10.7 1.1 0.7 2.2 0.7 7.0 47.9 3.5 0.0 0.0 9.2 0.0 9.5 1.1 0.0 0.0 5.7 1.7 4.3 149.5 5.1 0.0 0.0 0.3 0.0 259.9 183.3 2.6 3.7 0.0 0.5 6.4 0.1 9.3 0.0 0.4 0.0 0.0 0.0 19.7 11.4 176.1 1.7 10.6 6.5 0.7 50.7 0.0 0.0 0.1 1.1 0.0 183.6 1.4 0.6 0.0 1.4 0.0 1.5 13.1 65.8 74.7 0.7 5.4 1.3 10.5 29.4 2.2 0.8 0.0 0.3 MYBL1 "A-myb, AMYB" ENSG00000185697 "MYB proto-oncogene like 1" P10243 8 66562175-66614247 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.1;testis: 11.8" "Group enriched" "Detected in many" 6 "dendritic cells: 127.3;NK-cells: 107.1;Plasma cells: 40.2;Spermatocytes: 35.8;T-cells: 89.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.9;MAIT T-cell: 1.3" "Lineage enhanced" "Detected in single" "T-cells: 1.9" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 82.5;BJ hTERT+ SV40 Large T+ RasG12V: 69.4;Daudi: 87.7;HBF TERT88: 113.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA008791 Uncertain Supported Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA008791: AB_1078540" "unprognostic (1.11e-1)" "unprognostic (2.47e-2)" "unprognostic (2.57e-1)" "unprognostic (7.23e-4)" "unprognostic (2.26e-1)" "unprognostic (1.89e-2)" "unprognostic (6.67e-3)" "unprognostic (2.38e-1)" "unprognostic (1.25e-1)" "unprognostic (3.78e-2)" "unprognostic (1.13e-2)" "unprognostic (3.74e-3)" "prognostic unfavorable (2.03e-8)" "unprognostic (2.04e-1)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (5.87e-2)" 1.0 0.7 1.1 6.1 2.2 2.5 1.7 2.0 1.7 0.7 0.3 1.0 1.3 1.1 0.5 0.7 0.8 2.3 3.4 1.0 1.3 0.4 2.0 2.3 20.1 2.9 1.7 0.6 0.2 0.4 0.4 0.9 3.2 1.2 1.4 5.9 0.5 1.6 0.9 1.2 1.9 2.3 1.9 7.6 1.3 11.8 1.6 2.5 0.6 0.8 16.1 1.1 0.8 3.7 35.4 11.9 3.7 10.1 1.0 2.1 2.6 47.7 21.8 82.5 69.4 1.6 34.9 87.7 4.2 40.4 31.0 10.0 3.5 4.0 113.0 10.6 5.5 1.8 13.4 1.6 0.2 0.8 3.4 0.7 0.4 22.7 19.0 14.8 2.7 6.4 0.4 28.3 51.0 3.1 5.8 1.3 2.8 3.3 15.8 1.9 14.1 2.2 19.4 1.2 8.2 3.3 8.4 3.0 8.6 5.6 50.6 2.3 14.5 49.4 11.3 11.1 44.2 8.2 12.1 25.7 13.0 5.3 20.0 0.0 0.0 0.0 1.9 0.0 1.3 0.0 0.3 0.8 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.1 1.1 2.2 2.0 1.7 1.0 1.3 2.9 1.7 3.2 1.9 1.6 3.7 3.0 0.0 2.3 3.3 4.0 1.8 0.4 0.3 1.8 10.4 4.7 6.6 9.1 2.8 0.1 0.0 2.1 2.0 127.3 0.5 0.0 0.5 3.9 0.8 2.4 1.7 0.0 6.6 3.9 0.0 0.7 2.7 3.1 1.4 0.0 5.6 4.2 0.9 0.7 5.0 2.7 0.4 0.0 1.6 3.2 4.2 0.9 5.1 1.8 8.4 1.6 10.3 107.1 5.5 12.4 0.2 1.1 0.0 40.2 0.3 0.0 0.5 1.5 9.1 0.0 2.5 4.5 35.8 6.8 3.2 0.4 1.5 89.1 1.4 0.8 0.3 MYL9 "LC20, MLC2, MRLC1, MYRL2" ENSG00000101335 "Myosin light chain 9" P24844 20 36541497-36551447 "Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 8015.9" "Group enriched" "Detected in many" 4 "Breast myoepithelial cells: 860.2;Cardiomyocytes: 1856.1;Peritubular cells: 1891.9;Sertoli cells: 2143.1;Smooth muscle cells: 2525.7;Theca cells: 881.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.2;neutrophil: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 783.3;BJ: 1047.3;fHDF/TERT166: 844.3;hTERT-RPE1: 645.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 76.1" "HPA039262, HPA045244, HPA059197" Supported NA NA 34000000 "Cluster 52: Eosinophils - Transcription" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA039262: AB_2676418, HPA045244: AB_2679269, HPA059197: AB_2683944" "unprognostic (1.15e-1)" "unprognostic (5.05e-2)" "unprognostic (2.67e-3)" "unprognostic (5.38e-2)" "unprognostic (7.17e-2)" "unprognostic (5.06e-2)" "unprognostic (1.94e-1)" "unprognostic (1.82e-1)" "unprognostic (1.34e-1)" "unprognostic (2.59e-1)" "unprognostic (9.06e-2)" "unprognostic (8.90e-2)" "prognostic unfavorable (7.92e-7)" "unprognostic (1.90e-2)" "unprognostic (8.41e-2)" "unprognostic (1.20e-1)" "unprognostic (1.92e-2)" 944.6 948.6 61.6 347.0 76.7 5.2 649.5 63.3 132.2 1083.0 104.6 8015.9 270.5 2897.3 238.2 999.8 1643.3 364.3 2294.5 61.4 63.1 352.2 116.6 617.9 56.4 66.3 66.3 717.2 82.0 45.4 91.2 160.3 66.1 2347.4 345.8 22.8 200.7 2248.7 164.3 289.2 1287.7 2107.8 62.0 274.3 1946.4 260.7 66.5 27.4 431.7 111.4 23.2 4176.1 943.6 63.3 79.4 1.3 60.3 1.2 783.3 298.6 264.5 1047.3 450.9 541.3 349.9 612.3 9.1 0.2 535.6 844.3 120.6 29.4 0.2 2.4 125.7 0.9 0.2 16.7 114.4 57.3 500.4 0.4 17.7 420.8 54.4 359.9 1.6 645.9 19.2 0.0 2.4 28.0 461.7 0.2 0.3 7.8 24.0 16.1 5.6 0.4 0.0 5.8 4.6 5.8 0.6 4.1 11.1 26.6 0.6 257.5 232.9 15.6 137.0 510.9 220.1 75.5 1.0 0.8 4.0 2.3 194.3 0.8 0.6 0.0 0.1 2.2 0.0 0.0 0.0 0.9 0.0 0.1 0.3 0.2 0.0 0.0 1.9 0.2 0.0 0.4 0.0 7.2 61.6 76.7 63.3 132.2 61.4 63.1 66.3 66.3 66.1 62.0 66.5 63.3 325.3 394.2 52.3 0.0 6.6 60.7 320.2 167.1 21.6 1.4 36.8 860.2 1856.1 24.3 50.8 90.1 0.0 37.0 6.3 0.1 27.4 310.3 9.3 13.1 419.9 179.7 0.0 5.7 0.2 116.0 78.3 410.4 10.2 9.3 15.2 234.3 169.9 2.7 32.0 1.7 0.1 1.2 14.2 5.0 76.6 55.4 331.8 111.7 72.9 30.9 19.4 230.4 6.2 0.0 0.5 47.9 2.5 1891.9 6.4 156.9 105.5 42.1 31.8 6.1 2143.1 65.9 2525.7 16.3 9.5 6.5 53.4 26.8 14.7 881.1 2.0 61.9 MYO1B myr1 ENSG00000128641 "Myosin IB" O43795 2 191245185-191425389 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 255.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 330.2;Hepatocytes: 414.2;Sertoli cells: 203.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 360.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013607, HPA060144" Approved Enhanced "Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "HPA013607: AB_1854251, HPA060144: AB_2684211" "unprognostic (4.11e-3)" "unprognostic (7.36e-3)" "unprognostic (1.21e-1)" "unprognostic (4.83e-3)" "unprognostic (2.78e-1)" "unprognostic (1.59e-3)" "unprognostic (1.09e-2)" "unprognostic (1.15e-2)" "unprognostic (3.25e-3)" "unprognostic (5.85e-2)" "unprognostic (4.55e-1)" "unprognostic (9.31e-2)" "prognostic unfavorable (2.36e-5)" "unprognostic (2.22e-2)" "unprognostic (1.79e-1)" "unprognostic (1.47e-1)" "unprognostic (6.55e-2)" 42.9 7.3 9.2 15.4 7.8 0.6 27.4 3.5 11.4 13.3 5.8 23.7 13.2 16.2 16.6 15.9 9.2 26.7 19.1 7.1 5.3 25.6 255.5 74.9 11.3 4.2 8.9 14.0 49.3 34.6 5.8 48.4 6.0 15.1 22.0 21.5 12.8 17.7 9.2 15.3 13.4 20.1 3.9 8.2 12.2 9.6 13.2 17.4 19.3 13.6 10.5 25.4 14.3 6.7 102.5 51.7 82.6 24.9 22.4 95.0 74.6 190.8 93.9 129.0 127.4 63.9 8.9 0.1 31.0 220.5 52.1 221.0 27.4 164.3 161.1 0.3 23.9 0.2 22.6 82.3 52.1 2.2 0.6 38.6 111.1 135.0 360.0 47.6 23.8 42.4 0.2 0.4 120.7 43.5 39.7 12.4 53.9 6.7 81.2 50.5 52.6 7.7 51.0 42.8 41.8 109.0 64.5 11.1 57.9 70.2 10.1 3.1 29.1 122.7 61.5 75.0 22.7 0.9 0.5 1.1 74.4 0.4 69.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.2 7.8 3.5 11.4 7.1 5.3 4.2 8.9 6.0 3.9 13.2 6.7 95.8 330.2 112.5 1.6 3.6 76.7 58.2 78.7 31.9 1.4 29.0 22.9 7.9 45.8 84.3 69.9 0.0 5.2 0.8 30.4 0.0 120.4 2.9 13.0 20.2 60.5 58.5 10.7 22.3 44.6 26.5 40.3 18.3 18.1 3.8 129.1 5.0 414.2 4.2 0.0 38.0 24.6 34.6 10.5 10.0 3.8 5.0 2.3 26.6 70.3 1.0 72.2 0.0 1.0 0.8 38.1 54.1 9.1 0.4 112.2 4.5 1.2 48.2 2.7 203.8 32.6 160.1 2.4 21.0 13.9 28.1 3.4 3.3 44.9 38.0 47.1 MZB1 "HSPC190, MEDA-7, MGC29506, PACAP, pERp1" ENSG00000170476 "Marginal zone B and B1 cell specific protein" Q8WU39 5 139387467-139390081 "Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 89.8;lymphoid tissue: 272.2" "Cell type enriched" "Detected in many" 6 "Plasma cells: 4000.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory B-cell: 160.4;plasmacytoid DC: 569.3" "Group enriched" "Detected in many" 116 "B-cells: 160.4;dendritic cells: 569.3" "Group enriched" "Detected in some" 5 "Karpas-707: 581.5;RPMI-8226: 2193.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043745, HPA052694" Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA 350000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA043745: AB_10960359, HPA052694: AB_2681919" "unprognostic (4.97e-3)" "unprognostic (1.75e-2)" "unprognostic (4.23e-2)" "prognostic favorable (7.27e-4)" "unprognostic (2.21e-2)" "prognostic favorable (4.60e-5)" "unprognostic (6.57e-2)" "unprognostic (1.35e-1)" "unprognostic (6.45e-3)" "unprognostic (7.10e-3)" "unprognostic (2.57e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.15e-8)" "unprognostic (7.22e-2)" "unprognostic (3.14e-1)" "unprognostic (9.46e-2)" "unprognostic (7.36e-2)" 4.4 9.1 0.0 87.4 0.1 33.0 21.0 0.0 0.7 18.3 0.2 70.1 89.8 1.8 0.4 10.1 5.7 14.3 2.3 0.0 0.0 5.9 5.8 15.9 123.2 0.1 0.0 4.9 1.3 0.0 0.7 0.0 0.1 5.1 39.9 0.0 56.7 4.9 0.1 0.4 47.8 2.1 0.4 272.2 66.6 2.4 0.1 147.3 9.1 0.0 117.8 58.7 3.6 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 256.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 144.6 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 128.5 0.5 581.5 0.0 0.0 227.8 2.2 0.0 0.0 0.0 90.1 0.3 2193.9 0.0 0.0 0.3 0.8 0.0 11.4 0.0 0.0 3.1 0.1 0.6 0.0 1.8 0.1 0.0 262.0 16.7 223.0 0.1 0.4 0.0 0.0 0.1 0.1 1.5 0.1 3.0 160.4 0.6 1.1 0.5 75.6 0.1 0.2 3.1 2.7 0.0 569.3 0.2 26.1 0.0 0.1 0.0 0.7 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.3 0.4 6.4 10.1 0.0 665.7 2.5 1.3 0.1 0.0 0.0 3.7 3.2 1.1 4.3 2.0 0.0 0.0 0.1 235.0 0.9 0.0 0.1 0.1 1.8 0.4 2.0 1.2 49.3 0.0 0.0 0.1 2.0 6.1 0.4 2.5 0.1 11.4 14.0 0.1 0.0 0.0 1.1 0.0 7.1 3.4 1.1 0.0 4.7 540.7 0.0 1.0 0.0 4.1 0.0 0.0 0.1 0.4 0.0 4000.1 3.0 1.2 1.9 1.2 0.0 0.0 1.7 2.1 0.1 0.1 0.4 2.4 2.2 100.7 0.5 9.7 0.4 NAALADL2 ENSG00000177694 "N-acetylated alpha-linked acidic dipeptidase like 2" Q58DX5 3 174438573-175810548 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 311.5;Inhibitory neurons: 135.1;Microglial cells: 155.5;Oligodendrocyte precursor cells: 468.0;Oligodendrocytes: 532.9" "Cancer enhanced" "Detected in many" "prostate cancer: 5.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 14.5;BJ hTERT+: 5.4;fHDF/TERT166: 6.4;WM-115: 5.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA012413, HPA017425, CAB025586" Approved Enhanced Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "CAB025586: , HPA012413: AB_1854274, HPA017425: AB_1854275" "unprognostic (7.28e-3)" "unprognostic (1.10e-1)" "unprognostic (6.28e-2)" "unprognostic (1.60e-1)" "unprognostic (2.56e-1)" "unprognostic (2.56e-1)" "unprognostic (2.29e-4)" "unprognostic (3.44e-3)" "unprognostic (5.70e-2)" "unprognostic (7.42e-2)" "unprognostic (7.85e-3)" "unprognostic (9.49e-2)" "unprognostic (3.66e-6)" "unprognostic (7.11e-2)" "unprognostic (1.48e-1)" "unprognostic (9.05e-2)" "unprognostic (2.22e-2)" 2.4 1.1 1.1 1.0 2.3 0.2 5.8 1.2 1.4 6.3 1.1 3.0 1.7 3.7 5.5 1.5 3.8 4.2 2.6 1.4 0.6 3.3 2.9 2.0 0.5 2.2 1.3 3.9 2.2 10.2 0.5 1.2 1.8 4.9 2.4 1.6 5.8 3.7 1.0 0.8 1.6 3.5 1.4 1.9 2.7 0.9 1.5 1.2 2.3 1.7 0.5 3.8 1.2 3.3 0.0 0.0 0.3 0.0 4.4 14.5 0.1 3.1 5.4 0.7 0.9 0.2 1.7 0.0 0.6 6.4 0.2 0.1 0.0 0.0 2.3 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 4.1 0.8 0.1 0.0 3.8 0.5 0.0 0.0 0.1 3.1 0.6 0.2 0.0 0.0 2.2 0.0 0.0 0.2 0.1 2.2 0.3 0.1 0.1 0.3 0.3 1.2 0.3 4.0 0.2 0.7 2.9 0.1 0.1 0.6 0.0 0.0 0.0 1.9 0.1 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.1 2.3 1.2 1.4 1.4 0.6 2.2 1.3 1.8 1.4 1.5 3.3 5.1 0.0 11.5 311.5 0.1 2.3 8.9 2.7 1.2 7.7 35.1 13.7 3.0 12.8 9.1 12.9 12.5 19.6 0.3 11.1 7.9 10.1 74.9 23.7 8.7 2.8 9.0 2.7 113.4 2.5 1.4 15.0 23.9 30.2 4.5 3.4 2.9 4.5 1.8 0.0 135.1 2.6 10.2 0.3 3.0 39.6 15.2 1.1 3.6 155.5 0.0 6.7 0.0 468.0 532.9 3.6 4.4 12.0 0.0 13.6 13.2 2.4 21.9 6.2 0.0 23.4 4.9 3.2 2.8 5.3 1.8 12.3 0.8 5.7 16.4 16.0 NAV1 "DKFZp781D0314, FLJ12560, FLJ14203, KIAA1151, MGC14961, POMFIL3, steerin-1" ENSG00000134369 "Neuron navigator 1" Q8NEY1 1 201622885-201826969 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 169.1;Inhibitory neurons: 161.7;Oligodendrocyte precursor cells: 713.8;Oligodendrocytes: 224.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.4;myeloid DC: 2.1" "Group enriched" "Detected in many" 5 "dendritic cells: 2.1;granulocytes: 3.4" "Cell line enhanced" "Detected in many" "TIME: 187.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012302, HPA018127, HPA027887" Enhanced Approved Microtubules NA NA "Cluster 46: Basophils - DNA binding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" Microtubules "CAB012302: AB_776716, HPA018127: AB_1854317, HPA027887: AB_10601040" "unprognostic (2.14e-1)" "unprognostic (1.82e-1)" "unprognostic (4.12e-2)" "unprognostic (3.33e-2)" "unprognostic (1.14e-1)" "unprognostic (3.87e-1)" "unprognostic (1.79e-1)" "unprognostic (3.45e-1)" "unprognostic (9.10e-2)" "unprognostic (5.63e-2)" "unprognostic (4.68e-1)" "unprognostic (8.24e-2)" "prognostic unfavorable (3.10e-6)" "unprognostic (3.45e-2)" "unprognostic (2.16e-1)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" 19.6 2.7 17.4 8.2 18.3 1.6 15.2 8.0 17.7 11.7 0.0 12.3 3.7 10.1 4.3 8.6 7.2 7.5 26.6 17.5 20.3 4.6 1.9 11.1 4.1 24.6 17.9 3.7 4.4 5.2 5.2 11.8 15.1 7.5 5.4 5.4 7.8 6.7 4.8 7.7 6.2 10.3 9.9 3.6 5.3 4.4 21.8 2.8 9.4 6.7 3.7 14.9 12.6 32.5 1.6 2.9 29.0 3.8 84.3 69.5 51.7 44.6 43.0 35.5 30.9 0.0 15.7 0.6 0.7 61.4 19.4 21.5 22.0 14.9 28.4 2.5 3.2 1.4 5.6 0.0 22.5 0.2 19.1 30.6 5.4 62.4 36.0 94.9 80.7 1.8 0.8 2.6 29.8 0.4 0.0 0.1 42.4 0.7 1.7 3.9 65.0 9.3 4.8 4.3 21.9 4.5 11.1 47.6 14.5 19.2 0.4 1.2 187.8 54.5 11.1 54.7 39.4 8.1 2.3 0.2 59.2 5.9 47.5 3.4 0.5 0.1 0.2 0.3 0.1 0.3 0.2 0.0 2.1 0.3 0.2 0.1 0.0 0.1 0.3 0.5 0.0 0.3 17.4 18.3 8.0 17.7 17.5 20.3 24.6 17.9 15.1 9.9 21.8 32.5 77.4 3.2 1.5 169.1 3.1 11.0 2.2 5.9 8.0 34.6 4.8 4.3 29.2 1.5 4.8 12.9 0.0 14.9 0.9 4.7 0.0 13.0 3.6 1.6 6.4 39.3 52.8 1.7 98.2 8.3 54.1 45.8 8.2 4.4 17.7 54.5 21.0 0.7 14.5 25.2 161.7 3.4 6.1 18.3 15.8 3.8 10.8 15.1 23.2 69.3 60.6 11.8 1.0 713.8 224.6 21.7 4.2 0.7 4.9 2.3 0.9 0.6 3.5 4.0 6.6 119.3 18.8 0.6 2.6 16.9 7.0 15.7 2.0 6.6 5.0 3.2 NBL1 "D1S1733E, DAN, DAND1, NB, NO3" ENSG00000158747 "NBL1, DAN family BMP antagonist" P41271 1 19596979-19658456 "Predicted intracellular proteins, Predicted secreted proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 676.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 395.1;Leydig cells: 386.8;Paneth cells: 313.2;Peritubular cells: 356.9;Prostatic glandular cells: 293.3;Proximal enterocytes: 413.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 431.7;HSkMC: 305.6;SK-MEL-30: 473.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007394, CAB026132" Uncertain "Secreted in other tissues" NA NA 8100000 "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB026132: , HPA007394: AB_10601272" "unprognostic (1.65e-1)" "unprognostic (1.65e-2)" "unprognostic (9.03e-2)" "unprognostic (2.85e-1)" "unprognostic (1.33e-2)" "unprognostic (1.93e-1)" "unprognostic (1.18e-2)" "unprognostic (3.15e-2)" "unprognostic (3.92e-1)" "unprognostic (7.88e-2)" "unprognostic (3.10e-2)" "unprognostic (1.92e-2)" "unprognostic (1.39e-2)" "unprognostic (1.46e-1)" "unprognostic (2.39e-1)" "unprognostic (6.21e-2)" "unprognostic (2.26e-2)" 166.3 27.7 116.1 61.4 115.2 5.7 183.3 90.6 156.0 676.6 125.7 259.3 195.0 253.9 48.3 206.8 281.5 202.6 119.1 147.1 117.1 67.2 5.8 312.0 57.3 101.7 140.7 635.9 27.1 48.3 125.3 21.6 117.0 376.0 109.3 14.5 65.4 113.5 26.6 199.1 314.1 113.0 95.0 25.8 139.9 44.5 109.5 25.3 85.9 28.4 22.4 246.5 373.8 97.3 138.8 42.9 7.2 38.5 431.7 222.7 19.7 195.5 238.6 64.1 64.7 11.8 242.6 0.2 122.2 245.7 44.8 153.4 40.8 180.1 19.6 132.9 23.0 6.8 40.5 72.4 69.4 0.5 3.1 305.6 162.0 94.6 57.6 19.1 48.7 8.0 1.4 0.4 20.6 20.4 0.4 11.7 2.9 142.3 65.2 6.4 0.1 4.7 122.5 16.6 3.1 102.2 31.2 1.2 473.8 7.1 160.2 24.3 68.9 62.4 49.7 180.0 30.3 0.9 1.1 0.8 45.4 0.6 19.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.8 0.4 0.0 0.0 0.6 0.4 0.0 0.1 0.0 0.0 0.0 0.1 116.1 115.2 90.6 156.0 147.1 117.1 101.7 140.7 117.0 95.0 109.5 97.3 150.4 3.2 2.3 0.0 2.9 174.6 237.3 22.6 107.0 35.5 41.5 32.8 43.5 55.8 11.9 36.8 6.2 1.0 5.1 395.1 3.9 43.0 2.0 15.6 55.7 84.3 54.5 3.4 0.0 7.7 2.6 241.4 39.8 10.1 13.4 80.9 47.8 1.5 54.6 6.7 0.0 244.6 12.2 2.2 76.6 13.1 386.8 6.6 60.5 0.0 5.8 13.4 0.0 0.0 0.0 97.5 313.2 356.9 1.1 293.3 413.8 19.7 24.5 10.2 131.5 14.0 142.9 1.4 7.6 61.4 202.4 1.4 29.6 15.1 220.4 206.5 NCAM1 "CD56, NCAM" ENSG00000149294 "Neural cell adhesion molecule 1" P13591 11 112961247-113278436 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 290.1;heart muscle: 145.5" "Cell type enhanced" "Detected in many" "Astrocytes: 530.8;Excitatory neurons: 461.4;Inhibitory neurons: 441.2;Oligodendrocyte precursor cells: 939.0;Oligodendrocytes: 1013.5" "Cancer enriched" "Detected in many" 8 "glioma: 31.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 15 "NK-cell: 53.7" "Lineage enriched" "Detected in many" 15 "NK-cells: 53.7" "Cell line enhanced" "Detected in many" "HEL: 61.3;RH-30: 132.5;SCLC-21H: 107.4;SH-SY5Y: 52.7;U-138 MG: 72.8;WM-115: 79.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000142, CAB018071, HPA039835" Enhanced Enhanced "Plasma membrane,Cytosol" "Secreted in other tissues" NA NA 1200000 2300000000 "Cluster 48: NK-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" Cytosol "CAB000142: , CAB018071: AB_627129, HPA039835: AB_2676705" "unprognostic (7.04e-2)" "unprognostic (1.16e-1)" "unprognostic (2.77e-2)" "unprognostic (2.18e-2)" "unprognostic (2.91e-1)" "unprognostic (1.74e-3)" "unprognostic (2.82e-1)" "unprognostic (4.42e-3)" "unprognostic (2.13e-1)" "unprognostic (1.63e-2)" "prognostic favorable (9.11e-6)" "unprognostic (8.13e-2)" "prognostic unfavorable (8.20e-4)" "unprognostic (2.97e-2)" "unprognostic (2.24e-1)" "unprognostic (3.75e-2)" "unprognostic (5.82e-5)" 4.6 65.7 124.0 3.9 169.1 1.5 2.7 118.1 140.3 35.1 0.0 47.8 4.6 62.7 3.5 7.0 40.4 4.8 145.5 135.6 179.1 3.2 2.9 1.8 1.3 140.4 134.2 43.8 2.6 0.0 22.2 0.5 147.4 14.9 6.6 117.7 3.6 17.7 31.2 2.1 18.3 46.9 129.7 4.7 23.0 5.0 137.0 0.4 30.2 29.5 1.0 34.8 24.3 290.1 0.1 0.0 20.8 0.3 0.2 0.5 0.3 1.0 0.0 0.7 1.2 0.3 0.3 3.1 18.2 20.1 0.8 0.3 0.1 0.0 0.0 0.4 12.1 61.3 0.1 0.0 2.1 0.0 9.5 12.4 0.1 0.1 18.6 0.1 0.0 0.1 0.0 1.0 20.8 0.0 0.2 5.2 1.8 0.0 0.4 0.1 132.5 10.0 0.0 0.0 107.4 52.7 0.1 0.5 0.1 2.0 0.2 0.8 0.2 72.8 33.4 0.3 31.8 0.1 0.5 0.1 8.3 28.4 79.0 0.0 0.2 0.0 3.6 0.0 1.2 0.0 0.1 0.5 0.1 0.0 0.0 1.4 0.7 53.7 0.0 0.0 0.2 1.9 124.0 169.1 118.1 140.3 135.6 179.1 140.4 134.2 147.4 129.7 137.0 290.1 13.7 0.0 0.0 530.8 0.4 1.7 0.5 0.0 0.0 123.5 5.7 0.6 131.7 0.0 0.0 0.0 37.5 0.6 27.7 0.1 1.9 18.3 6.7 0.3 2.4 2.8 5.4 0.0 461.4 0.0 0.2 12.8 5.1 0.5 1.3 11.7 7.1 0.7 0.4 175.0 441.2 0.0 8.2 4.7 3.8 5.9 15.2 1.8 0.0 35.6 1.2 216.6 59.8 939.0 1013.5 1.3 0.0 10.1 5.6 0.4 0.0 0.2 0.7 98.0 0.0 107.5 4.8 1.0 2.8 0.4 1.7 0.1 13.4 5.6 0.0 0.2 NCKAP5 "ERIH1, ERIH2, NAP5" ENSG00000176771 "NCK associated protein 5" O14513 2 132671788-133568463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 34.8;lung: 11.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 262.8;Astrocytes: 478.6;Oligodendrocyte precursor cells: 774.6;Oligodendrocytes: 2156.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "AF22: 46.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034639, HPA044859" Uncertain Approved "Nucleoli,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoli "Golgi apparatus, Plasma membrane, Cytosol" "HPA034639: AB_10669678, HPA044859: AB_2679114" "unprognostic (2.54e-1)" "unprognostic (1.95e-2)" "unprognostic (2.30e-2)" "unprognostic (2.58e-2)" "unprognostic (2.49e-2)" "unprognostic (3.13e-1)" "unprognostic (7.07e-2)" "unprognostic (1.90e-1)" "unprognostic (1.96e-2)" "unprognostic (1.82e-2)" "unprognostic (1.46e-1)" "unprognostic (2.93e-1)" "unprognostic (1.06e-11)" "unprognostic (4.56e-2)" "unprognostic (1.17e-1)" "unprognostic (8.95e-2)" "unprognostic (1.03e-1)" 1.9 1.0 9.6 0.5 31.3 0.0 3.0 18.6 12.3 1.2 2.5 1.2 2.2 0.4 0.6 4.0 0.4 0.7 2.6 9.5 14.5 4.1 3.9 11.4 1.3 23.4 28.6 2.4 0.9 0.6 0.6 2.6 22.9 0.8 1.0 4.7 2.1 0.3 0.5 2.1 3.2 0.4 10.1 1.7 1.7 1.1 28.6 0.8 1.1 0.6 1.0 0.5 2.0 34.8 0.0 2.2 46.2 0.0 0.1 0.4 0.2 0.7 8.3 0.7 0.8 0.0 0.1 3.6 0.0 0.5 0.5 0.2 0.3 0.7 2.5 0.0 0.3 0.0 7.1 0.0 0.0 0.0 0.0 0.5 3.8 4.4 0.6 7.2 0.8 0.0 0.0 0.0 1.3 0.5 0.0 0.0 1.1 0.3 1.4 0.4 0.0 1.9 1.1 1.1 0.2 1.4 0.0 1.7 2.4 0.4 0.7 0.0 2.4 0.3 0.4 6.7 0.1 0.2 0.0 1.3 0.4 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 31.3 18.6 12.3 9.5 14.5 23.4 28.6 22.9 10.1 28.6 34.8 6.0 262.8 13.3 478.6 0.6 8.9 0.7 1.4 15.4 179.6 14.5 10.8 16.8 0.0 28.6 1.8 41.7 0.1 0.1 5.3 3.9 0.3 6.8 1.1 1.1 2.9 3.6 0.0 16.4 0.2 0.2 6.8 7.7 1.4 1.3 0.0 0.7 6.3 0.6 33.7 41.3 5.4 10.2 7.9 32.2 3.3 26.4 6.2 1.8 147.1 4.1 56.9 0.0 774.6 2156.8 1.0 5.2 7.5 0.0 0.5 20.7 14.0 1.2 7.8 6.6 8.7 24.7 0.1 1.3 15.5 2.8 0.0 0.7 0.0 1.6 1.5 NDRG2 "KIAA1248, SYLD" ENSG00000165795 "NDRG family member 2" Q9UN36 14 21016763-21070872 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis, Wnt signaling pathway" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1885.3;salivary gland: 2081.6;skeletal muscle: 1828.7" "Cell type enhanced" "Detected in many" "Astrocytes: 379.0;Distal tubular cells: 485.2;Muller glia cells: 548.0;Sertoli cells: 598.2" "Cancer enhanced" "Detected in all" "glioma: 78.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "myeloid DC: 204.4" "Lineage enriched" "Detected in all" 11 "dendritic cells: 204.4" "Cell line enhanced" "Detected in many" "Hep G2: 57.0;HMC-1: 39.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002896, HPA003590, CAB017491" Enhanced Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA 460000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 5: Muller glia cells - Visual perception" "Centriolar satellite" "Nucleoplasm, Cytosol" "CAB017491: AB_2298331, HPA002896: AB_1079459, HPA003590: AB_1079458" "unprognostic (9.27e-3)" "unprognostic (2.97e-3)" "unprognostic (1.26e-2)" "unprognostic (5.09e-3)" "unprognostic (2.00e-2)" "unprognostic (2.92e-2)" "prognostic favorable (6.71e-4)" "unprognostic (1.85e-3)" "unprognostic (5.57e-2)" "unprognostic (3.46e-2)" "unprognostic (1.69e-1)" "unprognostic (5.10e-2)" "prognostic favorable (1.43e-12)" "unprognostic (1.46e-1)" "unprognostic (5.56e-2)" "unprognostic (6.11e-2)" "unprognostic (4.19e-2)" 192.0 400.6 1613.1 27.4 1885.3 2.8 321.6 1623.2 1666.4 395.4 1189.8 198.3 72.1 229.7 260.3 229.5 305.0 130.7 327.2 1551.7 1590.0 150.1 544.4 115.5 48.6 1690.6 1686.1 476.1 93.7 278.5 88.5 45.3 1581.9 171.3 111.0 134.1 2081.6 208.0 1828.7 220.3 125.4 127.7 1584.5 152.0 130.9 33.3 1752.7 40.1 99.9 1591.4 100.4 158.0 265.8 1597.9 10.9 2.3 6.8 12.6 1.1 0.0 1.0 0.2 4.5 3.9 2.2 15.1 20.0 0.6 4.0 0.3 6.2 17.6 30.3 6.3 5.4 0.1 10.9 14.3 2.2 57.0 1.3 1.3 39.0 11.8 13.1 0.9 1.9 6.3 0.0 12.6 29.0 1.2 0.6 9.4 5.0 4.0 17.9 35.2 0.8 14.6 0.7 3.7 7.6 27.4 0.1 19.4 3.0 3.3 14.4 17.3 26.6 8.2 0.0 1.2 20.8 0.4 0.4 6.1 4.8 0.3 1.8 0.3 4.7 0.0 6.5 0.7 8.3 1.5 11.4 6.4 12.6 11.9 204.4 4.4 18.7 14.0 1.4 3.0 0.1 7.0 9.4 15.3 1613.1 1885.3 1623.2 1666.4 1551.7 1590.0 1690.6 1686.1 1581.9 1584.5 1752.7 1597.9 98.0 0.0 11.9 379.0 6.7 28.7 83.7 86.4 12.0 6.3 240.7 201.2 180.2 151.5 110.9 40.5 10.4 11.5 9.1 81.4 485.2 104.9 6.3 33.3 11.0 53.9 33.5 8.4 1.1 21.7 0.7 62.3 18.8 40.2 48.8 79.0 164.2 214.9 20.7 3.3 3.9 77.4 57.0 30.8 137.6 14.4 348.6 30.4 321.9 47.8 8.7 548.0 1.0 42.7 71.0 16.3 37.9 166.3 1.2 68.5 18.5 41.3 70.8 15.5 598.2 167.7 162.8 1.7 5.5 21.6 30.4 21.6 11.9 66.8 118.9 155.9 NECTIN3 "CD113, CDw113, DKFZP566B0846, nectin-3, PPR3, PVRL3, PVRR3" ENSG00000177707 "Nectin cell adhesion molecule 3" Q9NQS3 3 111070071-111275563 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 54.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.6;Syncytiotrophoblasts: 117.3;Theca cells: 31.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 117.4;TIME: 170.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009869, HPA011038" Approved Approved "Cell Junctions,Cytosol" NA NA 41000000 "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" Cytosol "Cell Junctions" "CAB009869: AB_2284699, HPA011038: AB_1079719" "unprognostic (3.76e-2)" "unprognostic (3.81e-3)" "unprognostic (1.74e-1)" "unprognostic (1.97e-2)" "unprognostic (1.02e-1)" "unprognostic (9.77e-2)" "unprognostic (3.26e-3)" "unprognostic (3.77e-1)" "unprognostic (7.58e-2)" "unprognostic (3.94e-2)" "unprognostic (5.33e-2)" "unprognostic (7.04e-2)" "prognostic favorable (9.82e-7)" "unprognostic (2.01e-1)" "unprognostic (1.97e-1)" "unprognostic (2.67e-1)" "unprognostic (1.05e-1)" 8.9 4.8 3.9 4.7 6.0 0.2 4.3 6.2 7.5 7.3 0.0 23.0 32.9 7.6 1.5 4.6 9.7 8.2 5.3 6.6 5.0 12.0 29.4 10.4 3.0 10.8 5.6 16.1 7.1 4.6 1.1 22.7 6.7 11.7 23.1 7.3 5.6 8.4 1.7 1.4 21.2 13.6 7.3 3.9 24.6 54.7 12.4 1.5 42.5 7.1 3.1 6.0 3.0 8.8 0.2 36.2 117.4 7.7 45.7 85.3 7.2 78.6 82.7 47.8 39.7 33.4 16.7 0.0 25.4 112.4 26.6 0.6 33.2 11.4 87.4 0.9 8.8 0.1 12.1 2.4 77.2 5.9 1.1 43.6 4.6 31.7 30.3 42.5 40.8 1.5 0.0 30.2 104.2 0.2 7.8 0.0 33.0 11.0 12.9 0.0 58.2 0.2 26.9 19.2 2.9 20.8 1.6 0.0 15.7 38.9 1.3 0.5 170.4 58.8 24.9 11.1 47.2 17.2 0.0 0.2 37.9 0.1 56.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.9 6.0 6.2 7.5 6.6 5.0 10.8 5.6 6.7 7.3 12.4 8.8 8.3 25.6 11.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 1.6 3.0 0.0 0.0 3.1 12.9 0.0 3.9 4.5 0.0 0.0 6.5 0.0 9.0 11.4 4.4 0.0 0.0 0.0 18.9 9.4 9.5 0.0 13.7 1.3 6.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 17.4 0.0 0.0 2.8 0.0 0.0 7.1 0.7 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 117.3 5.3 31.5 0.0 0.0 NET1 "ARHGEF8, NET1A" ENSG00000173848 "Neuroepithelial cell transforming 1" Q7Z628 10 5412557-5459056 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 242.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 8.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 252.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020068 Uncertain Approved Nucleoplasm,Vesicles Yes Yes "Cluster 32: T-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA020068: AB_2670348" "unprognostic (1.77e-2)" "unprognostic (1.87e-1)" "unprognostic (3.40e-1)" "unprognostic (4.05e-2)" "unprognostic (3.37e-3)" "unprognostic (2.15e-1)" "prognostic unfavorable (3.87e-5)" "unprognostic (6.31e-2)" "unprognostic (1.87e-1)" "unprognostic (2.77e-2)" "prognostic unfavorable (8.27e-4)" "unprognostic (2.26e-1)" "unprognostic (5.41e-2)" "unprognostic (1.20e-1)" "unprognostic (1.90e-1)" "unprognostic (3.01e-1)" "unprognostic (2.46e-1)" 48.8 10.8 35.5 23.4 34.2 40.5 52.8 38.5 57.6 43.7 52.8 92.2 56.2 41.8 56.2 68.4 46.2 35.9 13.2 30.2 32.4 49.3 45.1 22.2 26.7 41.8 37.2 28.5 37.9 5.4 10.6 65.7 43.8 41.3 88.2 6.5 93.1 24.3 25.0 39.8 74.7 36.9 37.5 8.1 77.8 14.4 41.1 30.4 26.2 28.0 33.0 60.8 59.3 40.1 115.9 67.7 45.2 51.0 26.8 11.9 252.9 69.1 37.6 53.4 50.4 36.4 215.2 40.6 27.7 42.4 11.4 185.5 54.9 104.3 63.9 38.1 38.5 77.5 22.9 84.0 7.2 21.5 31.1 18.2 61.0 54.0 12.3 47.6 31.1 42.6 138.5 64.4 30.0 54.3 74.3 30.6 61.5 158.6 51.0 45.0 85.0 32.4 33.4 57.6 38.5 20.6 60.7 110.9 20.3 76.2 36.7 65.3 29.5 20.3 30.9 30.7 56.0 39.3 23.1 53.4 18.1 33.1 43.4 2.0 0.6 1.4 0.6 1.0 0.0 1.4 1.2 0.4 4.9 0.6 8.7 1.7 0.1 0.8 0.4 2.0 4.0 2.2 35.5 34.2 38.5 57.6 30.2 32.4 41.8 37.2 43.8 37.5 41.1 40.1 18.4 32.1 55.8 2.6 12.7 40.3 127.2 49.0 103.0 11.0 52.6 28.3 12.1 41.5 84.3 12.9 4.2 110.2 8.4 242.2 5.9 13.1 2.4 97.7 30.6 42.7 80.8 54.1 5.1 24.4 109.1 33.2 107.0 131.4 15.2 16.9 12.5 55.7 14.5 3.3 7.7 145.3 34.6 10.5 59.8 2.4 21.8 31.2 35.6 44.0 48.7 3.8 0.0 8.5 5.7 62.1 148.3 87.6 39.2 67.8 123.6 29.2 85.7 3.5 111.7 183.0 185.0 26.3 16.0 158.1 32.4 117.5 9.3 2.9 145.0 186.5 NGF NGFB ENSG00000134259 "Nerve growth factor" P01138 1 115285904-115338770 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 20.8;ovary: 18.9" "Cell type enhanced" "Detected in some" "Inhibitory neurons: 15.7;Leydig cells: 29.2;Sertoli cells: 118.3;Smooth muscle cells: 51.6" "Cancer enhanced" "Detected in many" "renal cancer: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 87.9;BJ hTERT+ SV40 Large T+: 30.1;GAMG: 46.2;hTEC/SVTERT24-B: 29.8;hTERT-RPE1: 49.0;U-2197: 60.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Secreted in other tissues" NA NA 40000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "unprognostic (7.55e-2)" "unprognostic (2.66e-2)" "unprognostic (1.53e-3)" "unprognostic (8.85e-2)" "unprognostic (4.12e-1)" "prognostic unfavorable (1.80e-4)" "unprognostic (1.03e-1)" "unprognostic (5.30e-2)" "unprognostic (8.73e-3)" "unprognostic (4.28e-1)" "unprognostic (1.79e-1)" "unprognostic (2.05e-1)" "prognostic unfavorable (8.08e-7)" "unprognostic (1.15e-3)" "unprognostic (2.13e-1)" "unprognostic (7.99e-3)" "unprognostic (1.62e-4)" 13.9 2.5 1.7 1.6 1.7 0.0 4.0 1.3 2.1 7.1 2.1 5.0 0.1 8.8 1.4 1.1 13.2 1.7 20.8 1.6 2.2 6.4 4.0 1.6 0.5 1.9 1.7 18.9 0.8 0.4 2.7 1.1 1.9 2.6 0.6 0.1 2.1 1.0 0.9 0.9 2.1 4.0 1.4 3.7 2.1 1.1 1.9 0.2 3.3 1.1 0.1 5.5 5.0 1.6 0.0 0.3 0.0 0.0 1.8 0.1 0.0 87.9 9.9 30.1 21.9 0.0 0.0 0.0 1.9 21.1 46.2 3.6 0.0 0.6 13.8 0.0 0.2 0.0 0.6 0.0 12.1 0.0 0.0 0.1 0.6 29.8 21.6 49.0 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.0 3.0 0.0 1.3 0.0 1.2 0.0 0.0 0.0 1.1 0.3 1.6 0.6 0.0 3.9 0.0 0.0 0.8 1.8 3.7 60.0 3.5 0.0 0.0 0.0 3.6 0.0 19.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.7 1.3 2.1 1.6 2.2 1.9 1.7 1.9 1.4 1.9 1.6 0.4 0.0 0.0 0.3 0.0 3.1 0.5 3.9 0.0 0.0 0.1 1.5 0.7 1.5 0.2 0.0 0.0 3.0 0.0 0.0 0.0 5.6 0.2 0.2 0.8 0.8 0.0 0.0 0.3 0.0 1.3 7.3 0.0 0.3 0.0 0.0 4.2 0.0 0.1 0.0 15.7 0.0 2.0 0.0 1.7 0.4 29.2 0.2 1.8 1.9 0.0 0.0 0.0 12.1 0.5 0.1 0.0 6.0 0.0 0.6 0.0 0.0 0.1 0.0 118.3 0.8 51.6 0.3 1.0 0.0 2.3 2.5 0.6 0.0 0.0 0.3 NHSL1 "bA43P8.1, C6orf63, KIAA1357" ENSG00000135540 "NHS like 1" Q5SYE7 6 138422043-138692571 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.2" "Cell type enriched" "Detected in many" 4 "Astrocytes: 502.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.6;non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Hep G2: 46.2;TIME: 64.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029966, HPA029967" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 64: Astrocytes - Nervous system maintenance" "Nuclear membrane" Nucleoplasm "HPA029966: AB_10601972, HPA029967: AB_2673271" "unprognostic (1.85e-1)" "unprognostic (9.71e-2)" "unprognostic (6.19e-2)" "unprognostic (1.81e-1)" "unprognostic (1.01e-1)" "unprognostic (1.93e-1)" "unprognostic (3.27e-1)" "unprognostic (8.34e-2)" "unprognostic (5.21e-2)" "unprognostic (9.99e-2)" "unprognostic (1.10e-1)" "unprognostic (8.00e-2)" "unprognostic (4.19e-2)" "unprognostic (3.73e-2)" "unprognostic (1.52e-1)" "unprognostic (6.55e-2)" "unprognostic (4.06e-2)" 4.1 1.2 15.7 2.4 14.1 0.3 2.5 9.7 8.5 2.4 16.6 13.2 15.8 1.2 4.6 10.4 1.0 3.0 15.7 14.6 11.2 5.8 14.8 12.8 1.0 16.2 15.9 0.5 3.3 2.1 1.1 4.3 10.7 0.8 11.4 2.6 3.5 0.5 0.5 11.4 23.2 3.2 9.2 2.6 7.8 0.4 14.4 0.6 1.4 0.8 2.1 2.7 4.5 5.6 5.5 4.7 32.8 13.8 9.4 11.4 12.2 4.8 2.3 1.7 1.6 6.2 3.1 0.0 6.0 4.1 3.1 12.3 20.0 12.5 0.9 0.4 13.4 3.4 2.2 46.2 13.8 12.4 2.3 16.7 7.0 0.9 14.1 1.8 23.3 1.9 0.0 1.8 7.2 10.7 1.3 1.0 13.1 3.1 8.8 14.1 3.4 1.0 11.2 13.7 12.4 0.0 5.1 10.3 33.4 21.5 3.3 3.9 64.3 4.6 4.5 4.6 13.3 1.2 2.7 0.0 0.4 5.0 25.5 0.4 1.2 0.2 0.0 1.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.6 0.3 0.0 0.2 15.7 14.1 9.7 8.5 14.6 11.2 16.2 15.9 10.7 9.2 14.4 5.6 6.2 60.9 66.9 502.1 0.5 42.8 3.1 6.6 4.0 0.6 4.1 6.0 22.7 15.7 9.9 29.5 29.2 14.2 0.1 84.1 9.8 3.7 1.1 19.0 1.8 9.3 20.3 2.7 3.3 3.6 3.5 15.6 16.8 16.9 8.8 1.5 26.4 38.1 4.5 37.0 2.9 32.3 6.1 9.4 7.1 0.4 0.6 7.5 21.4 104.0 0.6 15.4 0.0 79.9 2.3 3.9 43.0 0.0 0.1 5.4 87.3 15.8 22.0 1.4 6.6 2.3 4.7 0.0 1.1 7.7 49.2 43.4 1.8 0.8 45.4 10.5 NID2 ENSG00000087303 "Nidogen 2" Q14112 14 52004803-52069228 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 60.8" "Cell type enhanced" "Detected in many" "Adipocytes: 31.0;Endothelial cells: 19.7;Fibroblasts: 46.0;Microglial cells: 19.7;Smooth muscle cells: 22.6;Theca cells: 19.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 15.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 285.4;ASC TERT1: 113.0;BJ: 152.1;BJ hTERT+: 131.8;HHSteC: 158.1;HSkMC: 591.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052460, HPA058772" Enhanced Enhanced "Plasma membrane" "Secreted to extracellular matrix" NA NA 6300000 "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane" "HPA052460: AB_2681840, HPA058772: AB_2683815" "unprognostic (6.51e-2)" "unprognostic (3.55e-3)" "unprognostic (3.73e-2)" "unprognostic (3.25e-2)" "unprognostic (2.04e-1)" "unprognostic (1.94e-1)" "unprognostic (5.37e-2)" "unprognostic (3.05e-3)" "unprognostic (2.52e-3)" "unprognostic (3.07e-2)" "unprognostic (4.85e-2)" "unprognostic (1.43e-1)" "unprognostic (1.48e-3)" "prognostic unfavorable (7.34e-4)" "unprognostic (4.58e-2)" "unprognostic (2.87e-2)" "prognostic unfavorable (2.78e-4)" 28.3 5.2 0.9 9.2 1.2 0.7 9.6 0.6 1.4 7.5 44.0 8.8 2.3 17.4 5.8 5.4 6.7 19.0 15.6 1.4 0.5 4.8 5.9 6.1 3.5 1.8 0.6 18.9 3.4 13.2 2.5 60.8 0.5 8.4 6.8 0.1 3.6 10.4 4.3 1.7 3.5 11.4 1.1 1.9 6.8 1.4 0.9 2.1 31.6 5.5 1.4 15.4 5.4 1.6 0.0 3.4 76.6 0.0 285.4 113.0 0.2 152.1 131.8 14.5 15.0 0.4 0.0 0.0 22.2 17.3 0.0 10.7 9.9 0.1 3.9 0.1 2.0 0.0 3.0 0.0 158.1 0.0 0.0 591.5 0.0 59.6 0.1 82.5 8.1 0.1 0.0 0.0 8.6 0.0 0.0 0.4 3.3 0.0 5.1 23.5 0.2 0.1 19.9 0.0 0.0 1.8 0.0 0.1 0.0 10.0 0.0 0.0 0.9 54.4 0.6 33.0 0.0 0.0 0.0 0.1 17.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.2 0.6 1.4 1.4 0.5 1.8 0.6 0.5 1.1 0.9 1.6 31.0 0.0 0.0 0.0 0.2 0.6 0.2 0.0 0.6 1.4 0.2 0.3 2.1 0.0 0.0 1.8 0.0 0.7 0.7 3.7 0.0 0.1 14.0 1.5 11.3 19.7 0.0 0.0 0.8 0.0 1.1 46.0 1.1 0.4 1.3 0.4 8.6 0.0 1.6 0.0 1.7 2.0 0.0 0.3 1.2 4.4 6.2 0.3 3.6 19.7 1.0 0.0 0.0 2.0 4.8 0.2 1.3 8.6 0.1 0.2 1.7 0.4 0.0 0.8 6.6 6.1 22.6 0.2 0.1 0.1 1.0 0.8 0.4 19.1 3.0 0.2 NINL "KIAA0980, NLP" ENSG00000101004 "Ninein like" Q9Y2I6 20 25452697-25585531 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 42.4;Granulosa cells: 29.6;Inhibitory neurons: 32.6;Oligodendrocyte precursor cells: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 37.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA000686 Uncertain Uncertain "Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" "Microtubules, Cytokinetic bridge, Cytosol" "HPA000686: AB_1079193" "unprognostic (7.33e-2)" "unprognostic (1.14e-1)" "unprognostic (1.13e-1)" "unprognostic (2.63e-2)" "unprognostic (4.84e-2)" "unprognostic (4.64e-2)" "unprognostic (1.16e-1)" "unprognostic (8.56e-2)" "unprognostic (2.50e-1)" "unprognostic (7.56e-2)" "prognostic favorable (1.47e-4)" "unprognostic (3.39e-1)" "prognostic favorable (1.03e-5)" "unprognostic (3.95e-2)" "unprognostic (2.72e-1)" "unprognostic (1.51e-1)" "unprognostic (6.26e-2)" 4.0 8.6 4.9 2.0 5.9 0.6 4.0 10.4 6.1 10.1 8.8 9.8 3.2 7.2 7.2 5.8 5.2 3.3 4.0 4.4 6.9 15.1 8.1 4.1 2.2 7.9 7.1 18.9 5.4 8.2 9.9 1.5 7.0 8.8 2.1 4.7 4.4 3.7 4.5 2.4 3.9 3.5 5.5 4.9 6.3 7.7 6.5 15.7 10.2 1.2 2.2 3.6 8.5 6.8 1.0 10.8 23.0 15.1 2.6 7.5 7.1 3.6 3.1 3.1 4.4 2.8 7.5 0.6 5.0 5.6 7.6 0.8 3.4 0.7 2.6 0.5 4.7 1.6 5.0 37.5 5.4 0.6 0.1 9.2 0.7 3.6 0.0 8.8 6.8 17.8 1.9 0.3 3.8 9.6 21.7 0.7 6.5 0.1 1.1 0.5 17.9 0.8 1.5 1.3 22.7 16.0 8.2 3.0 9.1 18.3 4.9 6.4 0.3 0.1 8.6 0.1 0.2 2.3 4.4 0.1 0.2 0.6 3.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 4.9 5.9 10.4 6.1 4.4 6.9 7.9 7.1 7.0 5.5 6.5 6.8 1.2 0.0 14.6 42.4 0.8 2.0 4.9 2.5 5.7 3.0 2.8 3.3 6.5 12.8 4.8 7.3 25.0 2.8 0.6 0.4 0.0 5.6 0.6 4.2 7.3 2.3 6.1 0.0 7.4 1.2 1.3 8.7 4.6 3.4 0.0 29.6 8.9 8.4 2.3 8.4 32.6 2.3 8.2 0.3 2.0 2.7 13.1 0.8 0.0 12.2 0.0 3.2 2.1 47.3 19.4 2.8 1.5 12.4 0.9 4.5 0.7 8.8 13.7 1.9 6.6 10.8 4.7 2.5 5.0 4.3 0.9 1.5 1.1 21.0 2.5 1.9 NIT1 ENSG00000158793 "Nitrilase 1" Q86X76 1 161118086-161125445 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 101.5;Proximal tubular cells: 116.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006657 Approved NA NA 89000 "Cluster 34: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA006657: AB_1079485" "unprognostic (3.66e-2)" "unprognostic (1.15e-1)" "unprognostic (7.16e-2)" "unprognostic (1.39e-1)" "unprognostic (1.47e-1)" "unprognostic (1.10e-2)" "unprognostic (1.55e-1)" "unprognostic (2.16e-1)" "unprognostic (4.70e-2)" "unprognostic (2.52e-3)" "unprognostic (2.18e-1)" "unprognostic (6.62e-2)" "prognostic unfavorable (4.21e-4)" "unprognostic (2.00e-1)" "unprognostic (1.76e-1)" "unprognostic (2.52e-2)" "unprognostic (2.94e-2)" 22.4 61.7 22.2 12.5 22.7 9.3 21.8 22.7 23.5 22.3 24.8 30.2 26.7 19.9 17.5 22.5 19.7 11.0 29.1 22.6 23.8 39.9 63.2 20.8 14.5 23.8 22.6 21.1 29.7 29.6 28.1 11.8 24.2 24.4 19.2 12.3 20.3 18.1 22.7 20.9 32.6 15.0 22.1 26.6 23.1 16.7 23.7 17.7 25.5 17.4 14.7 22.1 20.1 23.5 19.5 27.0 26.7 7.6 34.7 20.7 15.7 15.5 21.2 18.0 16.6 18.3 35.8 21.1 24.3 21.1 25.1 19.8 15.7 34.2 14.9 18.1 13.5 14.3 17.3 20.3 26.4 9.0 10.9 25.4 33.4 34.2 35.2 29.3 25.7 31.1 15.6 12.7 28.4 17.1 17.7 11.1 11.8 35.5 22.8 18.9 14.5 26.5 37.3 12.1 10.8 14.6 20.9 31.9 20.9 51.7 35.1 20.1 15.6 7.9 18.1 13.8 11.7 41.3 25.3 18.5 16.5 8.3 11.4 43.0 20.5 19.3 10.3 18.7 10.7 11.5 10.9 8.5 17.0 11.2 10.2 8.9 15.5 9.1 25.5 18.3 12.0 11.7 22.2 22.7 22.7 23.5 22.6 23.8 23.8 22.6 24.2 22.1 23.7 23.5 18.7 19.2 15.6 13.4 15.1 8.7 22.3 32.6 18.2 13.3 17.3 19.3 6.6 35.8 20.6 23.9 18.8 47.4 19.3 43.0 64.6 31.6 7.0 17.8 11.6 16.5 11.5 13.9 11.4 30.9 29.0 15.6 20.4 15.9 12.0 20.2 17.2 63.8 40.3 18.5 11.9 24.9 20.3 15.2 12.3 4.9 16.1 19.7 16.0 15.9 21.8 24.6 13.4 8.0 19.0 25.7 25.9 22.6 17.6 14.1 101.5 116.1 25.9 17.7 39.5 12.9 16.7 33.5 22.5 15.6 12.8 56.0 12.5 35.2 28.8 21.0 NLRP14 "CLR11.2, GC-LRR, Nalp-iota, NALP14, NOD5, PAN8" ENSG00000158077 "NLR family pyrin domain containing 14" Q86W24 11 7020479-7071526 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Astrocytes: 2.3;Bipolar cells: 2.2;Cone photoreceptor cells: 2.1;Distal tubular cells: 1.9;Early spermatids: 2.2;Excitatory neurons: 2.2;Rod photoreceptor cells: 3.2;Spermatocytes: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA039477 Approved Uncertain Cytosol NA NA "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol "HPA039477: AB_10794748" "unprognostic (6.46e-3)" "unprognostic (5.76e-3)" "unprognostic (1.44e-4)" "unprognostic (7.20e-4)" "unprognostic (5.57e-2)" "unprognostic (8.02e-3)" "unprognostic (6.57e-2)" "unprognostic (2.65e-1)" "unprognostic (2.68e-1)" "unprognostic (1.44e-1)" "unprognostic (2.68e-1)" "unprognostic (2.65e-2)" "unprognostic (3.17e-3)" "unprognostic (6.69e-2)" "unprognostic (3.22e-1)" "unprognostic (3.85e-2)" "unprognostic (1.25e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.5 0.1 0.1 0.2 0.2 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.2 0.1 0.2 0.0 0.4 0.0 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.9 0.1 2.2 0.3 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.5 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.2 0.0 0.0 0.0 2.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NOS3 "ECNOS, eNOS" ENSG00000164867 "Nitric oxide synthase 3" P29474 7 150991017-151014588 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Oxidoreductase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 62.4" "Cell type enhanced" "Detected in some" "Adipocytes: 20.4;Early spermatids: 81.9;Endothelial cells: 32.6;Hepatic stellate cells: 29.3;Late spermatids: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Lineage enriched" "Detected in single" 4 "T-cells: 2.3" "Cell line enhanced" "Detected in some" "BEWO: 23.1;HUVEC TERT2: 44.7;K-562: 16.6;TIME: 82.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002168 Enhanced NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002168: AB_564072" "unprognostic (6.53e-2)" "unprognostic (3.36e-1)" "unprognostic (1.63e-2)" "unprognostic (8.46e-2)" "unprognostic (2.96e-2)" "unprognostic (1.47e-1)" "unprognostic (1.35e-1)" "unprognostic (1.36e-1)" "unprognostic (6.97e-2)" "unprognostic (2.56e-1)" "unprognostic (9.40e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (3.63e-4)" "unprognostic (1.25e-2)" "unprognostic (6.63e-2)" "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" 19.3 6.3 8.4 5.8 6.8 0.8 13.2 5.7 6.7 7.3 3.4 5.9 2.6 9.7 0.4 5.8 8.1 4.7 20.6 5.7 6.1 24.2 4.3 11.2 2.7 9.2 7.7 3.2 2.9 1.2 7.2 4.8 8.6 7.6 1.2 0.8 4.4 1.7 3.9 4.2 6.7 3.7 7.5 62.4 5.4 7.2 11.0 0.6 9.1 3.5 1.2 9.7 7.4 6.0 0.4 0.1 1.3 4.0 0.0 0.0 23.1 0.0 0.0 0.0 0.0 0.3 2.2 0.4 2.1 0.0 0.2 0.7 0.0 0.1 0.0 0.0 0.4 2.2 0.3 6.4 0.6 0.5 10.4 0.1 0.2 0.0 0.0 0.1 44.7 5.1 16.6 3.6 0.0 0.0 0.2 0.5 1.7 0.7 0.1 3.0 0.0 1.8 0.0 0.3 0.5 0.4 0.2 1.4 0.0 0.4 0.1 1.4 82.5 0.2 0.7 0.4 0.1 2.4 8.9 2.2 0.0 7.5 0.0 0.2 0.1 0.1 1.1 0.2 0.7 0.3 1.7 0.9 0.2 0.5 2.3 0.9 0.3 0.2 0.2 0.2 2.1 0.5 8.4 6.8 5.7 6.7 5.7 6.1 9.2 7.7 8.6 7.5 11.0 6.0 20.4 9.6 2.2 0.3 0.7 0.9 0.1 0.1 0.0 0.2 0.2 0.3 3.1 0.0 0.7 0.0 0.0 0.2 0.7 0.1 0.0 1.0 81.9 4.9 0.7 32.6 0.0 0.0 0.2 0.0 0.1 2.9 0.5 3.2 5.7 0.7 29.3 0.7 0.4 0.0 0.2 0.4 0.0 0.6 0.5 29.3 0.9 0.4 0.0 7.5 0.0 0.3 0.0 0.0 0.0 0.8 0.0 1.2 1.5 0.4 0.1 0.2 2.2 0.3 0.0 0.6 2.6 6.9 5.3 0.2 0.6 3.6 1.6 0.9 0.1 0.9 NOTCH4 INT3 ENSG00000204301 "Notch receptor 4" Q99466 6 32194843-32224067 "Human disease related genes, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 24.2;breast: 19.8" "Group enriched" "Detected in many" 4 "Adipocytes: 263.8;Endothelial cells: 121.0;Hepatic stellate cells: 188.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA 6400000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.27e-1)" "unprognostic (2.27e-1)" "unprognostic (6.80e-3)" "unprognostic (9.50e-2)" "unprognostic (1.50e-1)" "unprognostic (1.81e-2)" "unprognostic (3.88e-2)" "unprognostic (3.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.67e-1)" "unprognostic (1.93e-3)" "unprognostic (2.00e-1)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.31e-2)" "unprognostic (1.66e-1)" "unprognostic (1.56e-1)" "unprognostic (3.13e-1)" 24.2 4.0 0.0 0.5 0.0 0.0 19.8 0.0 0.0 5.8 0.0 3.6 0.5 7.2 3.2 2.7 5.8 0.0 15.8 0.0 0.0 8.5 2.5 18.5 0.4 0.0 0.1 2.8 2.6 0.0 3.0 1.4 0.0 6.0 0.1 0.0 2.6 0.0 5.6 2.8 3.9 0.0 0.0 2.6 3.9 0.9 0.0 0.0 9.6 0.0 0.1 5.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 263.8 0.0 6.1 0.0 6.0 5.2 32.1 9.9 13.6 2.7 2.6 6.6 8.7 0.0 4.2 5.5 4.2 0.4 11.9 0.6 0.0 2.6 46.0 2.6 3.1 121.0 6.0 12.0 0.2 1.1 0.3 4.7 0.0 1.0 0.0 1.8 188.8 2.3 1.7 6.7 0.2 0.8 4.1 9.3 5.2 35.6 7.2 6.8 3.6 10.3 1.6 21.0 0.0 0.0 0.5 0.4 0.3 5.3 0.7 18.0 1.0 0.9 3.1 3.6 0.0 7.8 9.3 5.5 1.9 1.9 1.6 0.3 3.6 3.7 0.9 5.6 NOVA2 "ANOVA, NOVA-2, NOVA3" ENSG00000104967 "NOVA alternative splicing regulator 2" Q9UNW9 19 45933734-45974044 "Human disease related genes, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.7" "Cell type enhanced" "Detected in some" "Adipocytes: 39.4;Bipolar cells: 56.7;Endothelial cells: 32.0;Excitatory neurons: 21.8;Hepatic stellate cells: 42.5;Horizontal cells: 21.9;Inhibitory neurons: 20.9" "Cancer enriched" "Detected in many" 4 "glioma: 5.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.7;HDLM-2: 11.0;HUVEC TERT2: 16.9;SH-SY5Y: 5.6;TIME: 25.8;U-2 OS: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045607 Enhanced Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" No No "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 56: Bipolar cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Nuclear bodies" "HPA045607: AB_10962628" "unprognostic (9.84e-2)" "unprognostic (2.07e-1)" "unprognostic (9.68e-2)" "unprognostic (2.01e-1)" "unprognostic (1.79e-1)" "unprognostic (3.04e-3)" "unprognostic (1.46e-1)" "unprognostic (6.21e-2)" "unprognostic (2.36e-1)" "unprognostic (3.02e-3)" "unprognostic (6.42e-5)" "unprognostic (1.16e-1)" "prognostic unfavorable (3.04e-4)" "unprognostic (5.05e-2)" "unprognostic (2.54e-1)" "unprognostic (1.41e-1)" "unprognostic (8.31e-2)" 6.7 1.9 12.4 0.7 15.1 0.0 5.7 0.5 16.7 3.2 0.0 1.8 0.6 3.4 0.6 1.4 2.9 1.4 6.7 16.0 5.8 4.7 1.0 9.3 0.5 4.6 3.0 1.2 1.1 1.0 6.2 3.9 3.6 2.3 0.5 5.6 1.1 0.8 2.3 1.1 1.7 2.0 0.6 1.5 1.5 2.0 4.6 0.4 4.5 2.5 0.2 2.5 2.0 9.8 0.0 0.1 9.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 1.3 0.0 0.0 11.0 0.4 0.0 0.1 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 25.8 0.0 5.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 15.1 0.5 16.7 16.0 5.8 4.6 3.0 3.6 0.6 4.6 9.8 39.4 0.0 0.0 5.9 0.1 0.6 0.2 0.0 0.6 56.7 0.1 0.5 3.4 1.5 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 3.8 0.1 0.1 32.0 0.0 0.0 21.8 0.2 0.0 1.2 0.0 0.1 0.0 0.1 42.5 0.5 0.1 21.9 20.9 0.0 0.0 1.6 1.5 3.5 0.0 0.1 0.0 9.4 0.0 1.3 0.0 11.6 9.5 0.2 0.0 0.4 1.2 0.3 0.0 0.0 0.0 3.3 0.0 0.6 0.6 2.4 2.3 0.3 0.1 0.0 0.5 0.4 0.0 0.3 NPAP1 C15orf2 ENSG00000185823 "Nuclear pore associated protein 1" Q9NZP6 15 24675775-24683393 "Predicted intracellular proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.8;testis: 2.9" "Cell type enriched" "Detected in some" 5 "Granulosa cells: 125.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018828, HPA019562" Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Vesicles, Plasma membrane" "HPA018828: AB_2669941, HPA019562: AB_2670190" "unprognostic (4.40e-2)" "unprognostic (1.85e-2)" "unprognostic (6.98e-3)" "unprognostic (7.45e-2)" "unprognostic (9.90e-2)" "unprognostic (1.08e-2)" "unprognostic (5.11e-3)" 0.0 0.0 0.9 0.0 1.8 0.4 0.1 0.1 1.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.5 1.7 0.9 0.0 0.0 0.1 0.9 0.7 0.5 0.4 0.0 0.5 0.0 0.5 0.1 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.5 0.1 0.1 2.9 1.5 0.0 0.5 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.9 1.8 0.1 1.1 0.5 1.7 0.9 0.7 0.5 0.5 1.5 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.1 0.2 0.7 0.1 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.1 0.0 125.9 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.0 0.8 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.3 24.1 12.7 0.0 0.0 0.0 0.0 0.5 0.0 0.2 NPDC1 "CAB-, CAB1, DKFZp586J0523" ENSG00000107281 "Neural proliferation, differentiation and control 1" Q9NQX5 9 137039463-137046179 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 397.0;Endothelial cells: 307.2;Enteroendocrine cells: 281.6;Hepatic stellate cells: 406.2;Intestinal goblet cells: 589.1" "Cancer enhanced" "Detected in all" "prostate cancer: 146.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 12.3;MAIT T-cell: 14.7;memory CD4 T-cell: 19.0;memory CD8 T-cell: 18.9;T-reg: 15.9" "Lineage enriched" "Detected in many" 5 "T-cells: 19.0" "Cell line enhanced" "Detected in many" "MCF7: 138.4;RPMI-8226: 132.8;T-47d: 140.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008189 Approved Approved Nucleoplasm,Cytosol NA NA 240000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm Cytosol "HPA008189: AB_1854584" "unprognostic (6.94e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (2.01e-5)" "prognostic favorable (6.19e-5)" "unprognostic (2.06e-1)" "unprognostic (4.83e-3)" "unprognostic (1.24e-1)" "unprognostic (4.35e-2)" "unprognostic (8.65e-2)" "unprognostic (1.53e-1)" "prognostic favorable (3.18e-4)" "unprognostic (2.40e-1)" "unprognostic (2.65e-2)" "unprognostic (1.23e-2)" "unprognostic (2.35e-1)" "unprognostic (4.20e-2)" "unprognostic (8.84e-2)" 129.5 45.7 140.8 12.2 128.1 3.4 133.0 110.6 181.3 130.5 55.0 93.1 23.4 121.6 4.3 53.7 148.6 24.9 149.1 143.3 143.1 75.9 23.7 115.4 13.0 138.9 142.3 68.2 81.2 23.0 266.0 21.1 131.3 260.5 13.4 9.2 137.4 35.1 34.0 56.4 72.1 16.9 120.7 145.2 126.2 35.3 142.9 2.9 68.4 12.4 3.9 97.9 90.5 114.7 33.6 41.9 10.1 67.1 23.7 23.8 2.8 68.7 23.0 16.9 6.7 17.1 18.5 30.3 50.7 28.6 4.6 122.4 8.6 20.5 1.6 25.0 40.4 13.6 123.7 12.9 33.3 11.9 0.3 16.5 31.9 8.7 17.9 43.1 43.6 13.2 0.7 0.8 3.5 138.4 1.0 1.1 21.1 111.0 68.1 19.9 0.0 132.8 28.6 22.7 77.2 50.0 18.4 65.3 46.5 3.6 140.1 17.9 73.9 12.4 21.6 84.1 21.0 0.1 0.4 1.4 17.7 1.2 10.5 0.0 0.6 0.9 12.3 0.1 14.7 0.1 19.0 18.9 1.1 0.0 0.5 3.1 0.0 0.2 0.1 3.4 15.9 3.3 140.8 128.1 110.6 181.3 143.3 143.1 138.9 142.3 131.3 120.7 142.9 114.7 397.0 0.0 7.7 64.3 3.4 23.6 77.6 15.0 31.3 97.5 174.0 139.7 18.3 71.4 19.8 29.5 16.7 1.1 5.5 122.2 0.0 52.5 1.8 39.0 27.7 307.2 281.6 19.3 71.7 66.0 1.3 61.2 153.9 101.3 0.0 9.2 406.2 1.9 22.2 62.2 64.7 589.1 18.3 21.0 20.0 6.9 161.2 6.6 30.2 37.5 3.0 38.5 1.0 38.2 39.0 33.0 106.0 145.6 1.4 234.9 37.5 0.7 7.5 62.0 39.5 23.9 38.9 2.8 19.0 15.9 23.7 1.8 12.3 9.1 98.1 103.1 NPY5R NPYR5 ENSG00000164129 "Neuropeptide Y receptor Y5" Q15761 4 163343892-163351934 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 7.2;lymphoid tissue: 8.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 4.6;Granulosa cells: 1.4;Inhibitory neurons: 3.5;Smooth muscle cells: 3.1;Spermatocytes: 3.0" "Cancer enhanced" "Detected in single" "breast cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (4.63e-6)" "unprognostic (3.00e-1)" "unprognostic (2.79e-1)" "unprognostic (2.13e-1)" "unprognostic (1.24e-1)" "unprognostic (3.74e-2)" "unprognostic (3.94e-2)" "unprognostic (5.40e-2)" "unprognostic (4.30e-2)" "unprognostic (3.99e-2)" "unprognostic (1.76e-1)" "unprognostic (3.94e-1)" 7.2 3.3 0.9 0.3 2.2 0.0 1.7 0.0 1.5 0.7 0.0 0.3 0.0 0.7 1.0 0.2 0.8 0.5 0.7 1.1 2.8 4.6 1.0 0.3 2.4 0.2 0.4 0.2 1.0 0.7 0.3 2.9 0.2 0.2 0.3 0.2 3.7 0.9 0.1 0.8 0.1 0.7 1.1 8.8 0.2 5.1 0.8 0.1 0.7 0.4 0.1 0.3 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 2.2 0.0 1.5 1.1 2.8 0.2 0.4 0.2 1.1 0.8 0.6 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.0 0.0 0.5 0.0 0.0 4.6 0.0 0.0 0.7 0.0 0.0 0.0 1.4 0.7 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 1.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 3.1 3.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 NR3C2 "MLR, MR" ENSG00000151623 "Nuclear receptor subfamily 3 group C member 2" P08235 4 148078762-148444698 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 265.8;Excitatory neurons: 275.7;Inhibitory neurons: 269.9;Microglial cells: 176.1;Oligodendrocyte precursor cells: 230.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 1.8" "Lineage enriched" "Detected in single" 6 "T-cells: 1.8" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 9.7;HUVEC TERT2: 6.0;Karpas-707: 6.9;PC-3: 6.1;RPTEC TERT1: 7.8;TIME: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009155, HPA074979" Enhanced Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "CAB009155: AB_2155949, HPA074979: AB_2686724" "unprognostic (2.75e-3)" "unprognostic (2.63e-2)" "unprognostic (6.70e-3)" "unprognostic (1.52e-1)" "unprognostic (4.09e-1)" "unprognostic (7.82e-3)" "unprognostic (1.04e-2)" "unprognostic (1.11e-2)" "unprognostic (1.14e-1)" "unprognostic (4.35e-2)" "unprognostic (4.97e-2)" "unprognostic (2.39e-1)" "prognostic favorable (3.10e-11)" "unprognostic (1.42e-1)" "unprognostic (1.87e-1)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" 4.6 4.5 4.5 3.7 5.6 1.0 4.8 9.2 11.7 5.6 4.0 21.8 8.7 6.2 3.8 3.1 5.9 5.8 9.4 13.7 3.5 12.1 8.5 7.3 3.1 3.0 5.9 14.7 7.6 12.5 5.5 1.8 3.0 3.7 26.2 8.5 10.7 4.3 12.1 3.0 15.3 4.9 3.2 5.2 8.3 4.3 6.1 2.9 19.7 14.1 2.1 5.9 3.3 4.8 0.0 0.0 0.0 0.0 0.4 0.3 0.4 0.0 0.0 0.0 0.4 0.0 0.0 1.4 2.6 1.0 0.2 0.0 1.3 0.7 0.1 0.2 2.3 0.2 0.6 0.0 0.0 1.7 0.3 0.1 0.0 0.0 0.0 9.7 6.0 0.9 0.0 6.9 2.0 0.0 0.0 0.0 0.1 1.2 6.1 0.5 0.0 0.1 7.8 0.1 0.1 0.0 0.0 1.4 0.6 0.1 0.7 0.0 8.7 4.3 2.5 0.1 0.8 0.0 0.0 0.1 1.4 0.6 1.0 0.0 0.0 0.0 0.5 0.0 1.8 0.1 0.7 0.4 0.0 0.2 1.0 1.1 0.0 0.0 0.2 0.0 0.2 0.1 4.5 5.6 9.2 11.7 13.7 3.5 3.0 5.9 3.0 3.2 6.1 4.8 11.9 28.9 13.9 265.8 5.1 2.0 2.2 0.4 6.2 10.3 6.2 5.8 20.3 7.2 6.7 11.0 18.8 0.9 1.0 76.1 9.8 3.0 68.2 2.1 1.1 8.2 18.0 0.0 275.7 5.8 0.5 5.9 13.7 2.6 5.7 6.4 8.6 7.0 0.6 13.5 269.9 44.6 6.1 2.9 2.4 41.8 4.4 1.7 7.2 176.1 1.2 8.1 1.0 230.2 95.7 3.2 26.8 3.8 0.8 1.8 26.4 2.3 4.7 9.6 0.0 14.7 5.1 1.8 5.6 2.6 1.7 0.1 4.9 1.8 21.5 2.1 NRG3 ENSG00000185737 "Neuregulin 3" P56975 10 81875194-82987179 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 17.3;retina: 5.2" "Group enriched" "Detected in some" 18 "Astrocytes: 2921.6;Excitatory neurons: 3761.0;Inhibitory neurons: 3088.3;Oligodendrocyte precursor cells: 1175.2" "Cancer enhanced" "Detected in many" "melanoma: 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.3;SK-MEL-30: 2.7;U-2 OS: 2.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075789 Uncertain Vesicles "Secreted in brain" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA075789: " "unprognostic (6.15e-3)" "unprognostic (2.43e-2)" "unprognostic (1.65e-5)" "unprognostic (1.89e-1)" "unprognostic (7.03e-4)" "unprognostic (1.85e-2)" "unprognostic (1.06e-1)" "unprognostic (7.05e-2)" "unprognostic (9.33e-2)" "unprognostic (1.82e-1)" "unprognostic (1.21e-1)" "unprognostic (3.75e-2)" "unprognostic (3.31e-4)" "unprognostic (1.04e-1)" "unprognostic (7.68e-3)" "unprognostic (7.27e-4)" 0.1 0.4 16.4 0.3 11.4 0.0 1.3 0.0 17.3 0.1 0.0 0.4 0.1 0.0 0.0 0.1 4.7 2.8 0.4 16.1 2.6 0.7 0.5 0.7 0.1 1.2 6.3 0.0 0.1 0.1 2.0 0.3 0.4 0.1 0.1 5.2 2.6 0.2 0.0 0.6 0.1 0.1 2.5 0.1 0.3 1.8 9.9 0.0 0.2 0.1 0.0 0.1 0.0 3.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 2.7 0.2 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.4 11.4 0.0 17.3 16.1 2.6 1.2 6.3 0.4 2.5 9.9 3.5 0.1 0.0 0.0 2921.6 0.1 0.0 0.0 0.0 0.0 15.9 0.7 0.6 0.8 2.8 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.9 31.4 0.0 0.0 0.7 0.0 0.0 3761.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 3088.3 0.0 0.0 0.0 0.0 12.8 0.6 0.1 0.0 148.0 0.0 6.7 0.0 1175.2 50.2 0.2 0.0 0.7 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.2 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 NRN1 NRN ENSG00000124785 "Neuritin 1" Q9NPD7 6 5997999-6007605 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 98.9;parathyroid gland: 81.0" "Cell type enhanced" "Detected in many" "Adipocytes: 262.9;Endothelial cells: 115.3;Excitatory neurons: 71.9;Extravillous trophoblasts: 64.7;Hepatic stellate cells: 160.3" "Cancer enhanced" "Detected in all" "glioma: 38.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "MAIT T-cell: 2.6;neutrophil: 2.2" "Group enriched" "Detected in many" 7 "granulocytes: 2.2;T-cells: 2.6" "Cell line enhanced" "Detected in many" "ASC diff: 140.0;ASC TERT1: 107.6;fHDF/TERT166: 147.5;JURKAT: 134.8;REH: 196.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 23000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 14: REH - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (6.24e-2)" "unprognostic (2.47e-2)" "unprognostic (1.35e-2)" "unprognostic (1.22e-1)" "unprognostic (1.26e-2)" "unprognostic (5.57e-2)" "unprognostic (4.70e-3)" "unprognostic (2.02e-2)" "unprognostic (1.03e-1)" "unprognostic (1.49e-1)" "unprognostic (1.67e-2)" "unprognostic (3.35e-1)" "prognostic unfavorable (4.79e-5)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (2.90e-1)" "unprognostic (4.37e-3)" 66.4 5.1 49.1 6.4 44.9 0.5 64.2 46.0 80.8 16.2 17.0 21.3 3.7 9.4 4.0 8.2 13.6 11.2 19.7 98.9 27.7 8.2 4.4 15.6 9.6 30.4 29.9 4.7 2.9 81.0 12.3 42.1 32.5 10.1 4.7 23.4 8.7 7.4 17.3 18.8 10.8 10.5 22.1 15.7 10.3 0.6 60.1 3.6 9.4 16.1 3.5 13.8 17.0 45.9 16.7 0.6 1.4 0.1 140.0 107.6 19.1 2.6 0.0 11.8 16.1 0.2 0.1 0.0 2.5 147.5 25.0 0.5 43.3 0.0 11.4 26.1 21.2 13.7 0.0 0.0 0.0 58.0 43.7 17.3 0.0 10.5 0.0 0.1 57.4 134.8 0.2 0.6 42.5 0.1 89.7 2.6 0.1 0.0 0.0 196.3 47.7 0.4 0.2 0.2 24.9 9.2 0.0 0.8 13.9 0.2 0.4 16.4 12.1 56.4 1.6 21.4 36.5 0.1 2.2 0.9 85.8 0.2 8.9 0.0 0.1 0.0 0.1 0.1 2.6 0.3 0.2 0.3 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.2 0.0 0.1 49.1 44.9 46.0 80.8 98.9 27.7 30.4 29.9 32.5 22.1 60.1 45.9 262.9 0.0 1.3 7.2 1.6 10.5 0.1 0.0 1.2 6.7 1.4 2.4 2.5 1.5 0.0 0.0 2.1 1.5 1.0 0.0 0.0 0.1 0.1 0.0 0.1 115.3 0.0 0.0 71.9 0.5 64.7 15.9 0.0 0.1 0.0 0.0 160.3 0.9 1.8 3.3 3.0 0.0 0.0 4.1 21.5 0.4 0.9 1.4 16.0 8.4 0.5 4.5 0.0 13.6 8.3 0.2 0.0 0.0 1.4 0.4 0.0 0.0 0.0 20.2 0.0 4.4 18.3 0.4 0.3 0.6 11.2 1.4 1.9 0.1 0.0 0.7 NTRK2 TRKB ENSG00000148053 "Neurotrophic receptor tyrosine kinase 2" Q16620 9 84668551-85027054 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 230.0;thyroid gland: 116.9" "Cell type enhanced" "Detected in many" "Astrocytes: 1144.3;Excitatory neurons: 750.1;Inhibitory neurons: 877.7;Oligodendrocyte precursor cells: 557.9" "Group enriched" "Detected in many" 5 "glioma: 31.6;head and neck cancer: 8.0;lung cancer: 9.8;thyroid cancer: 26.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.7;HaCaT: 3.0;RPTEC TERT1: 9.7;SH-SY5Y: 11.2;SuSa: 4.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007637, CAB010346, HPA074873" Enhanced Supported "Plasma membrane" NA NA 20000000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "CAB010346: AB_2155274, HPA007637: AB_1080385, HPA074873: " "unprognostic (2.75e-3)" "unprognostic (3.48e-2)" "unprognostic (1.82e-2)" "unprognostic (3.26e-1)" "unprognostic (9.26e-2)" "unprognostic (2.56e-2)" "unprognostic (1.29e-2)" "unprognostic (9.16e-2)" "unprognostic (6.13e-2)" "unprognostic (1.05e-1)" "unprognostic (4.25e-2)" "unprognostic (2.18e-2)" "unprognostic (2.66e-2)" "unprognostic (1.20e-2)" "unprognostic (1.21e-2)" "unprognostic (1.31e-1)" "unprognostic (1.39e-3)" 40.5 2.7 201.9 1.7 177.8 0.1 62.2 133.3 190.6 9.8 69.8 5.9 0.4 3.9 3.9 8.2 5.6 33.3 15.2 173.3 230.0 20.4 1.8 10.0 3.1 119.4 218.9 9.7 34.3 2.5 10.1 1.8 151.7 4.7 3.6 41.2 14.4 19.1 2.9 11.6 1.6 3.3 116.6 10.9 1.9 2.4 222.1 4.0 116.9 13.8 4.3 4.9 12.0 117.7 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 3.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 9.7 0.7 0.7 11.2 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.3 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 201.9 177.8 133.3 190.6 173.3 230.0 119.4 218.9 151.7 116.6 222.1 117.7 17.4 0.0 0.5 1144.3 0.7 56.6 1.0 1.8 93.9 30.3 144.1 116.8 11.4 0.0 0.2 9.2 6.2 0.0 1.0 8.7 27.4 36.1 1.8 1.2 0.4 8.0 0.0 0.0 750.1 0.7 0.1 76.6 0.0 2.3 0.0 0.1 5.0 0.0 0.2 242.3 877.7 0.7 0.0 0.0 14.2 3.6 104.1 1.4 17.8 65.6 0.6 241.0 0.0 557.9 109.5 0.5 7.0 48.2 0.3 0.9 0.0 7.1 1.7 12.2 124.9 9.9 114.4 0.8 2.3 5.2 24.6 0.0 3.3 0.2 7.2 0.9 OAZ2 ENSG00000180304 "Ornithine decarboxylase antizyme 2" O95190 15 64687573-64703281 "Predicted intracellular proteins" "Polyamine biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 324.9;Sertoli cells: 374.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 418.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047694 Uncertain Approved "Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "HPA047694: AB_2680121" "unprognostic (2.67e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (9.05e-4)" "unprognostic (2.09e-2)" "unprognostic (4.44e-2)" "unprognostic (2.32e-3)" "unprognostic (3.46e-2)" "unprognostic (7.94e-2)" "unprognostic (3.11e-2)" "unprognostic (5.24e-2)" "unprognostic (1.76e-3)" "unprognostic (1.78e-1)" "unprognostic (2.24e-2)" "unprognostic (7.50e-2)" "unprognostic (2.99e-1)" "unprognostic (2.54e-1)" "unprognostic (1.45e-1)" 65.1 68.5 110.1 49.5 111.8 32.9 55.1 112.2 112.5 61.1 108.0 72.4 28.4 64.7 57.2 44.4 59.8 46.9 79.3 110.1 114.5 68.4 89.3 55.8 50.7 112.6 114.6 56.5 35.9 96.8 75.0 75.1 112.4 53.3 35.8 123.4 45.3 49.1 207.9 45.9 40.9 72.3 114.3 89.8 47.7 80.8 114.4 41.7 65.8 152.5 45.4 56.3 48.3 116.4 71.2 63.5 130.6 43.5 91.8 79.4 24.6 80.5 120.6 113.4 98.5 43.5 62.2 61.6 72.7 113.4 84.5 37.5 126.7 71.6 99.2 82.4 48.3 40.3 48.3 32.5 52.2 35.7 125.7 104.4 49.6 57.0 40.1 147.4 109.2 42.9 30.1 29.6 123.4 45.3 24.5 43.8 223.1 39.1 50.7 57.5 74.5 54.0 102.0 55.7 68.4 125.1 30.4 45.0 80.3 161.6 75.6 52.7 66.0 76.4 102.2 38.0 87.0 65.1 104.6 58.2 87.4 75.2 69.8 22.1 145.3 268.4 29.3 247.8 24.2 30.2 24.6 24.0 91.1 29.1 27.9 25.3 418.0 39.5 209.6 49.4 30.7 115.5 110.1 111.8 112.2 112.5 110.1 114.5 112.6 114.6 112.4 114.3 114.4 116.4 67.5 25.6 43.5 15.3 36.1 121.7 99.5 67.7 47.8 93.8 57.9 40.4 61.9 44.3 41.0 42.3 104.3 114.1 33.4 19.2 168.3 109.5 324.9 35.2 30.0 109.3 81.9 33.3 14.6 66.0 70.9 61.3 14.3 20.5 103.3 36.9 134.6 83.6 133.9 74.0 13.6 26.0 91.6 115.4 238.1 80.9 114.3 86.6 103.2 20.6 114.2 268.2 49.4 12.1 26.9 81.8 25.7 68.1 19.1 88.9 29.2 94.2 51.1 180.8 374.7 68.1 160.9 166.2 83.9 28.0 121.2 68.5 31.7 44.3 27.4 72.4 OMD "osteoadherin, SLRR2C" ENSG00000127083 Osteomodulin Q99983 9 92412380-92424471 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 66.8;Hepatic stellate cells: 26.4;Leydig cells: 97.9;Peritubular cells: 110.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "ASC diff: 6.1;ASC TERT1: 5.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069948 Approved "Nucleoli fibrillar center,Endoplasmic reticulum" "Secreted in other tissues" NA NA 21000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "Nucleoli fibrillar center" "HPA069948: AB_2732144" "unprognostic (1.18e-1)" "unprognostic (2.33e-3)" "unprognostic (5.04e-2)" "unprognostic (2.26e-1)" "unprognostic (9.42e-2)" "unprognostic (1.87e-2)" "unprognostic (4.31e-3)" "unprognostic (6.42e-2)" "unprognostic (4.53e-1)" "unprognostic (3.89e-2)" "unprognostic (1.18e-1)" "unprognostic (1.65e-1)" "unprognostic (2.02e-3)" "unprognostic (5.81e-3)" "unprognostic (6.35e-2)" "unprognostic (2.84e-3)" "unprognostic (2.08e-3)" 13.9 6.9 2.4 0.3 3.2 0.2 12.6 3.0 6.0 15.5 4.1 4.8 0.8 7.6 7.5 4.3 9.4 8.1 20.0 2.4 2.3 1.9 1.1 4.6 0.9 2.3 2.4 12.0 1.7 0.8 3.9 2.8 2.5 5.0 1.9 0.1 2.2 3.4 1.3 3.3 3.2 8.4 2.3 0.4 4.4 3.1 2.4 0.9 8.9 11.3 2.8 5.5 3.9 2.2 0.0 0.0 0.0 0.0 6.1 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.3 0.4 0.4 0.4 0.0 0.3 0.6 0.5 0.2 0.2 0.1 0.3 0.5 0.4 2.4 3.2 3.0 6.0 2.4 2.3 2.3 2.4 2.5 2.3 2.4 2.2 4.4 0.0 0.0 0.0 0.3 2.7 0.4 0.1 0.0 0.9 0.1 0.1 1.3 4.3 0.6 1.8 0.0 0.1 0.4 0.0 0.0 0.0 0.4 0.3 11.4 7.8 0.0 0.0 1.7 0.0 0.2 66.8 2.0 0.3 0.0 0.1 26.4 0.0 0.3 0.0 1.5 0.0 0.0 0.3 3.3 3.2 97.9 0.2 1.8 9.4 0.0 0.0 0.0 1.0 1.6 0.0 0.0 110.2 0.8 0.2 0.0 0.1 0.0 1.6 0.0 2.2 2.9 0.2 0.1 0.3 2.7 0.0 0.4 0.1 0.0 0.2 ONECUT2 OC-2 ENSG00000119547 "One cut homeobox 2" O95948 18 57435374-57491298 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.1;gallbladder: 10.1;intestine: 10.1;liver: 8.5;retina: 5.4" "Cell type enriched" "Detected in many" 5 "Horizontal cells: 964.0" "Group enriched" "Detected in many" 7 "liver cancer: 4.3;pancreatic cancer: 4.3;stomach cancer: 5.4" "Group enriched" "Detected in many" 5 "basal ganglia: 9.1;cerebral cortex: 2.3;hypothalamus: 4.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 20.3;HeLa: 14.1;RT4: 6.7;SCLC-21H: 10.1" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "basal ganglia: 8.7;cerebellum: 4.7;cerebral cortex: 5.6;hippocampal formation: 3.2;hypothalamus: 2.5" HPA057058 Enhanced Supported "Nucleoplasm,Actin filaments" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 20: HeLa - Mitochondria" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Actin filaments" "HPA057058: AB_2683323" "unprognostic (3.02e-2)" "unprognostic (5.36e-2)" "unprognostic (9.06e-3)" "unprognostic (3.79e-5)" "unprognostic (1.13e-2)" "unprognostic (4.48e-4)" "unprognostic (2.10e-2)" "unprognostic (1.81e-1)" "unprognostic (3.75e-1)" "unprognostic (4.56e-3)" "unprognostic (8.66e-3)" "unprognostic (1.16e-2)" "unprognostic (5.34e-4)" "unprognostic (3.83e-2)" "unprognostic (2.58e-1)" "unprognostic (1.13e-1)" "unprognostic (3.21e-1)" 0.0 0.1 0.4 0.0 9.1 0.0 0.0 0.8 2.3 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 10.1 0.0 0.3 4.2 0.1 8.5 0.0 0.0 0.6 0.3 0.0 2.3 0.8 0.8 0.0 0.8 0.0 0.0 5.4 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 1.0 1.2 3.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 1.4 0.0 3.4 0.0 0.1 20.3 3.1 0.7 14.1 3.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 2.3 4.0 0.7 0.0 0.5 1.9 0.0 0.1 1.6 0.7 0.0 1.2 0.0 1.6 6.7 10.1 1.7 0.1 0.0 0.2 0.1 0.5 0.7 0.0 1.0 1.3 0.2 0.2 0.3 3.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 9.1 0.8 2.3 0.3 4.2 0.6 0.3 0.8 0.0 1.0 0.2 0.3 0.0 0.0 2.3 0.0 0.1 0.2 0.0 0.0 4.5 0.4 1.1 2.8 184.5 0.0 7.3 14.6 0.0 0.0 2.0 0.0 79.7 4.9 0.2 0.1 0.5 8.9 0.0 38.7 8.8 0.1 0.3 0.0 0.3 0.0 0.5 5.3 47.0 1.0 964.0 1.8 0.6 0.0 1.3 0.0 3.2 0.3 0.1 0.0 1.0 0.0 3.0 0.0 3.5 1.0 38.7 3.3 0.0 0.0 0.4 0.1 0.1 0.0 5.6 0.0 0.9 0.7 1.9 2.0 0.0 0.1 0.0 0.1 0.2 0.5 0.0 ORAI3 "MGC13024, TMEM142C" ENSG00000175938 "ORAI calcium release-activated calcium modulator 3" Q9BRQ5 16 30949068-30956461 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 77.3;Hofbauer cells: 93.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 94.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015022 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Cytosol" "HPA015022: AB_1854807" "unprognostic (1.17e-1)" "unprognostic (3.88e-2)" "unprognostic (2.94e-3)" "unprognostic (1.15e-2)" "unprognostic (8.29e-2)" "unprognostic (1.46e-1)" "unprognostic (8.60e-2)" "unprognostic (8.54e-2)" "unprognostic (3.15e-1)" "unprognostic (1.33e-3)" "unprognostic (1.77e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (3.87e-5)" "unprognostic (2.30e-2)" "unprognostic (4.46e-2)" "unprognostic (6.43e-3)" "unprognostic (9.17e-3)" 17.3 34.1 18.0 8.2 16.5 17.6 15.2 16.9 17.1 24.4 26.0 22.7 9.2 18.3 16.3 15.4 19.2 9.9 16.7 15.3 16.3 19.3 70.2 14.2 11.9 18.6 18.5 18.9 17.7 18.9 18.0 14.9 17.1 26.3 8.6 4.0 14.6 17.0 7.9 14.3 16.1 9.8 17.4 22.5 17.1 15.6 20.5 11.2 16.4 8.1 10.6 27.2 20.2 17.7 2.8 15.8 8.1 10.7 68.1 60.7 0.6 9.3 62.3 6.8 17.2 1.5 26.1 3.9 20.7 17.9 27.5 12.7 1.4 17.6 4.6 12.3 5.2 10.2 4.9 16.1 94.9 11.2 30.5 65.5 45.9 13.1 25.5 63.8 11.7 2.2 11.7 20.6 22.1 10.8 0.7 42.6 6.6 9.1 4.3 8.6 6.3 30.8 26.2 6.8 2.0 13.5 8.4 2.6 14.9 19.5 19.7 45.5 8.5 5.1 3.5 11.4 2.2 50.4 4.0 3.1 25.3 26.4 7.9 23.2 8.7 26.6 3.4 9.2 3.6 7.1 1.8 2.7 8.5 6.7 2.2 2.9 15.3 11.7 12.6 9.5 2.7 3.3 18.0 16.5 16.9 17.1 15.3 16.3 18.6 18.5 17.1 17.4 20.5 17.7 12.1 6.4 10.8 0.0 23.9 7.9 24.5 25.6 32.5 1.5 11.1 19.6 6.9 5.7 11.6 16.5 2.1 28.1 25.9 11.1 13.7 21.4 61.1 16.5 21.8 16.5 15.0 16.2 0.0 11.4 2.7 25.9 4.1 10.5 7.0 17.9 23.6 77.3 93.8 35.3 0.0 11.3 10.2 43.7 11.5 36.7 53.1 31.4 21.4 0.0 39.1 24.4 17.5 0.0 0.0 9.5 18.4 43.2 18.1 14.0 9.5 48.2 14.7 3.6 26.3 11.0 14.0 26.5 2.5 17.0 4.5 4.4 9.7 61.0 5.8 20.4 OSGIN1 "BDGI, OKL38" ENSG00000140961 "Oxidative stress induced growth inhibitor 1" Q9UJX0 16 83931311-83966332 "Predicted intracellular proteins" "Differentiation, Growth regulation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 147.4" "Cell type enhanced" "Detected in many" "Early spermatids: 56.2;Hepatocytes: 78.4;Late spermatids: 261.1;Proximal enterocytes: 99.0" "Cancer enriched" "Detected in all" 5 "liver cancer: 65.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 12.6" "Group enriched" "Detected in many" 8 "granulocytes: 4.2;monocytes: 12.6" "Cell line enhanced" "Detected in many" "A549: 66.8;Hep G2: 103.7;T-47d: 73.3;WM-115: 62.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA019239 Approved Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA019239: AB_1854779" "unprognostic (8.36e-2)" "unprognostic (9.44e-2)" "unprognostic (4.28e-2)" "prognostic favorable (4.89e-5)" "unprognostic (3.31e-3)" "unprognostic (9.14e-3)" "unprognostic (2.51e-2)" "unprognostic (3.57e-2)" "unprognostic (1.06e-1)" "unprognostic (2.75e-1)" "unprognostic (7.63e-2)" "unprognostic (9.20e-2)" "unprognostic (2.80e-2)" "unprognostic (2.45e-2)" "unprognostic (2.48e-2)" "unprognostic (8.28e-3)" "unprognostic (1.89e-1)" 8.5 26.5 7.0 4.8 8.3 0.8 7.1 7.6 7.0 4.0 4.3 7.4 31.3 3.3 1.2 12.3 4.5 8.4 10.1 5.2 7.3 14.1 147.4 9.3 1.3 10.1 9.0 4.3 8.5 3.0 3.7 1.6 10.2 5.6 2.5 2.0 5.2 2.2 22.4 3.3 18.7 1.6 5.5 10.5 13.9 15.2 9.3 0.8 13.2 9.6 1.2 12.8 5.7 9.3 4.7 66.8 0.8 2.9 4.1 5.9 5.0 7.7 7.5 7.0 2.5 16.9 24.0 0.1 18.0 6.7 31.5 12.6 3.2 4.9 2.6 1.1 0.8 1.2 15.5 103.7 15.0 2.3 25.7 3.6 3.9 18.1 4.1 3.9 7.2 4.8 6.5 6.5 9.1 31.9 0.9 0.9 0.6 16.5 15.8 2.3 6.7 3.3 4.8 5.9 0.4 1.5 16.0 5.1 32.6 1.7 73.3 2.7 23.1 10.6 16.0 15.7 5.3 2.7 1.2 0.2 35.6 3.6 62.8 0.1 2.2 0.0 0.0 5.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 4.2 0.0 12.6 0.0 0.0 1.0 7.0 8.3 7.6 7.0 5.2 7.3 10.1 9.0 10.2 5.5 9.3 9.3 2.2 16.0 3.9 0.0 0.6 1.5 8.1 15.7 5.2 0.8 7.9 4.3 9.0 8.6 18.5 1.8 0.0 1.4 0.5 41.8 5.9 11.3 56.2 6.1 1.0 5.4 4.2 0.0 0.1 6.6 0.4 5.4 26.0 5.3 1.3 2.7 6.1 78.4 10.5 0.0 0.1 12.9 12.2 9.4 3.0 261.1 4.1 7.3 7.2 0.0 3.0 8.6 0.0 0.0 0.2 13.2 23.5 12.0 1.3 11.8 99.0 11.7 5.0 0.6 13.1 4.7 5.1 2.3 1.3 6.0 1.7 1.4 0.6 4.6 10.5 5.9 OVGP1 "CHIT5, MUC9" ENSG00000085465 "Oviductal glycoprotein 1" Q12889 1 111414319-111427735 "Plasma proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 134 "fallopian tube: 2071.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 9.7;Excitatory neurons: 10.4;Glandular and luminal cells: 12.0;Inhibitory neurons: 8.5;Syncytiotrophoblasts: 17.4" "Group enriched" "Detected in many" 13 "endometrial cancer: 58.7;ovarian cancer: 27.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 4.9;OE19: 6.4;SK-BR-3: 5.0" "Region enhanced" "Detected in many" "cerebellum: 5.9" "Not detected" "Not detected" "HPA031666, HPA062205" Enhanced Supported Vesicles,Microtubules "Secreted in female reproductive system" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" Vesicles Microtubules "HPA031666: , HPA062205: AB_2684710" "unprognostic (1.52e-1)" "unprognostic (2.06e-2)" "unprognostic (3.35e-2)" "prognostic favorable (1.36e-4)" "unprognostic (8.39e-2)" "unprognostic (3.58e-2)" "unprognostic (2.33e-2)" "unprognostic (3.34e-2)" "unprognostic (5.44e-2)" "unprognostic (3.82e-2)" "unprognostic (7.68e-3)" "unprognostic (2.58e-1)" "unprognostic (5.35e-3)" "unprognostic (2.39e-1)" "unprognostic (1.38e-1)" "unprognostic (3.86e-3)" "prognostic favorable (3.93e-5)" 4.1 1.6 7.6 1.1 7.8 1.9 3.5 8.0 10.6 3.8 5.8 3.4 1.1 15.4 5.1 3.0 2071.7 1.1 2.3 7.7 7.0 5.0 8.0 3.9 2.2 7.3 6.9 6.7 1.5 6.8 2.4 2.0 7.2 5.5 2.2 4.3 4.2 1.5 2.6 7.6 5.2 1.4 6.5 4.6 2.8 9.2 6.9 1.2 2.4 1.0 2.0 4.6 3.8 8.2 0.4 0.4 0.9 0.5 1.8 2.0 1.7 0.2 1.4 0.3 0.7 0.6 0.0 0.8 1.7 0.6 0.0 0.5 0.3 0.3 0.5 2.0 4.9 0.3 0.8 2.4 0.6 0.9 2.2 1.8 2.9 0.0 1.0 1.4 0.4 3.2 0.3 1.5 0.1 0.5 0.6 1.2 0.2 6.4 1.7 0.6 0.2 0.7 1.4 3.7 0.6 0.6 0.1 5.0 0.7 2.4 0.3 0.8 0.8 0.1 0.2 2.5 0.7 1.8 0.5 0.4 0.2 1.6 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 7.6 7.8 8.0 10.6 7.7 7.0 7.3 6.9 7.2 6.5 6.9 8.2 1.2 0.0 1.1 3.3 0.6 3.1 1.1 0.3 0.0 2.1 1.7 1.9 0.6 0.0 0.5 0.0 0.0 5.6 0.2 1.1 1.9 0.2 4.0 9.7 0.7 1.6 0.0 0.0 10.4 0.0 2.6 0.6 0.0 12.0 0.0 1.0 1.4 2.9 0.6 0.0 8.5 1.5 2.0 0.6 1.4 6.1 1.5 0.5 0.0 3.7 0.0 0.4 0.0 1.5 2.4 0.2 0.5 1.9 0.1 1.6 0.6 2.8 1.3 0.6 0.0 0.7 1.1 3.8 0.7 1.0 3.1 17.4 0.8 0.2 1.6 1.6 OXER1 "GPCR, GPR170, TG1019" ENSG00000162881 "Oxoeicosanoid receptor 1" Q8TDS5 2 42762481-42764261 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 56.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 8.3;Proximal enterocytes: 16.1;Skeletal myocytes: 12.9" "Cancer enhanced" "Detected in all" "liver cancer: 12.9" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "basophil: 67.0;eosinophil: 144.5" "Lineage enriched" "Detected in many" 79 "granulocytes: 144.5" "Cell line enhanced" "Detected in some" "CACO-2: 6.6;Hep G2: 7.6;HMC-1: 6.1;REH: 3.2;THP-1: 2.8" HPA051433 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "HPA051433: AB_2681485" "unprognostic (6.77e-2)" "unprognostic (4.20e-2)" "unprognostic (3.13e-2)" "unprognostic (1.07e-1)" "unprognostic (4.09e-3)" "unprognostic (4.45e-3)" "unprognostic (7.80e-2)" "unprognostic (4.40e-2)" "unprognostic (1.18e-1)" "unprognostic (1.55e-1)" "unprognostic (3.42e-3)" "unprognostic (5.39e-2)" "unprognostic (1.82e-3)" "unprognostic (5.83e-2)" "unprognostic (1.66e-1)" "unprognostic (4.89e-2)" "unprognostic (5.46e-2)" 2.1 1.8 1.2 1.5 1.2 2.4 1.9 0.3 1.8 6.9 1.1 3.9 5.0 3.1 2.3 2.4 3.6 1.4 2.4 1.3 0.6 8.4 56.3 1.9 1.2 0.9 0.9 9.1 7.2 0.3 3.8 1.7 0.7 6.6 1.8 0.3 1.5 1.7 0.9 3.1 8.5 0.8 0.4 4.9 2.3 1.2 1.0 1.0 2.2 0.4 1.1 6.0 4.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 6.6 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.3 2.2 0.0 7.6 0.0 0.1 6.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 1.4 0.0 0.0 3.2 1.0 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.6 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 67.0 1.8 144.5 0.1 0.6 0.0 0.2 0.0 0.0 1.4 0.1 0.0 0.0 16.9 0.0 0.1 0.2 0.0 0.8 1.2 1.2 0.3 1.8 1.3 0.6 0.9 0.9 0.7 0.4 1.0 0.6 0.1 0.0 0.5 0.7 0.1 0.5 0.6 0.2 0.6 1.6 0.4 0.6 0.4 2.8 0.2 1.8 0.0 0.1 0.0 1.9 1.9 0.6 0.0 0.1 2.0 0.1 1.2 0.0 0.0 2.0 0.1 2.0 0.0 0.1 2.5 0.4 0.4 8.3 1.0 0.0 0.0 3.4 0.0 1.3 1.2 0.3 3.4 1.5 3.6 1.0 3.0 0.9 0.0 0.0 0.0 0.6 5.3 1.9 0.0 0.5 16.1 4.9 0.2 0.0 0.0 12.9 1.1 0.3 0.2 0.3 0.1 0.3 1.1 0.3 5.1 0.3 P2RY10 P2Y10 ENSG00000078589 "P2Y receptor family member 10" O00398 X 78945332-78963727 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.4" "Cell type enhanced" "Detected in some" "B-cells: 79.3;granulocytes: 29.2;Langerhans cells: 38.5;monocytes: 32.5;Plasma cells: 32.6;T-cells: 55.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "basophil: 256.1" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 5 "Karpas-707: 121.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036757, HPA065766" Enhanced NA NA "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA036757: AB_10696786, HPA065766: AB_2685556" "unprognostic (3.02e-3)" "unprognostic (1.47e-3)" "unprognostic (1.50e-6)" "unprognostic (6.62e-3)" "unprognostic (1.19e-1)" "unprognostic (1.13e-4)" "unprognostic (3.33e-2)" "unprognostic (8.30e-2)" "unprognostic (1.13e-2)" "unprognostic (4.13e-3)" "unprognostic (1.01e-1)" "unprognostic (8.66e-2)" "prognostic unfavorable (3.63e-4)" "unprognostic (2.23e-1)" "unprognostic (6.54e-2)" "unprognostic (3.85e-2)" "unprognostic (3.99e-2)" 0.8 0.5 0.4 14.6 0.5 8.2 0.9 1.4 1.1 1.0 0.0 2.7 3.1 0.8 0.3 1.1 0.4 3.2 0.4 0.4 0.1 0.4 1.6 2.4 27.4 0.2 0.0 0.4 1.5 0.0 0.1 0.3 0.2 1.3 3.6 0.6 1.2 0.2 0.2 0.6 6.4 0.7 0.0 16.6 3.9 0.3 0.2 10.3 0.6 0.1 25.8 5.4 0.4 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 14.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.2 0.3 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 121.8 0.0 0.1 0.2 0.2 0.2 0.0 0.2 0.2 0.2 9.9 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.2 0.2 0.1 0.0 26.5 0.1 1.4 0.2 0.3 0.1 256.1 0.2 158.1 12.6 0.9 11.4 73.1 28.0 25.5 4.0 74.1 25.7 19.5 27.9 18.1 10.9 2.8 41.7 13.2 0.4 0.5 1.4 1.1 0.4 0.1 0.2 0.0 0.2 0.0 0.2 0.5 0.7 0.0 1.7 0.0 79.3 1.8 0.0 0.0 0.0 0.0 0.3 0.3 1.2 0.0 0.6 0.0 0.0 0.0 15.0 0.0 0.0 0.2 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.4 0.0 0.8 0.5 0.1 29.2 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.6 38.5 0.0 0.0 3.6 8.8 0.0 32.5 0.0 9.2 0.0 0.0 0.0 0.0 0.0 32.6 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.1 2.0 0.0 55.1 0.0 0.0 0.3 PACRG "FLJ32724, Glup, HAK005771, PARK2CRG" ENSG00000112530 "Parkin coregulated" Q96M98 6 162727132-163315492 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 35.7;testis: 29.5" "Cell type enhanced" "Detected in many" "Early spermatids: 310.9;Excitatory neurons: 124.3;Inhibitory neurons: 174.9;Late spermatids: 369.8;Respiratory ciliated cells: 118.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SCLC-21H: 6.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066293 Enhanced NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA066293: AB_2685652" "unprognostic (3.06e-2)" "unprognostic (1.81e-2)" "unprognostic (1.59e-1)" "unprognostic (1.56e-2)" "unprognostic (2.48e-1)" "unprognostic (1.84e-1)" "unprognostic (6.26e-4)" "unprognostic (1.37e-1)" "unprognostic (1.76e-1)" "unprognostic (3.34e-1)" "unprognostic (8.31e-3)" "unprognostic (1.48e-1)" "prognostic favorable (2.55e-6)" "unprognostic (1.00e-1)" "unprognostic (3.68e-2)" "unprognostic (8.35e-2)" "unprognostic (2.93e-3)" 0.8 2.5 13.6 1.1 15.2 5.7 2.0 5.9 14.2 2.3 13.2 1.2 1.4 5.3 9.7 3.0 35.7 5.1 13.0 11.9 12.5 10.2 4.8 3.8 1.4 15.1 15.7 4.2 4.3 2.0 23.7 0.4 10.9 3.4 2.4 7.5 2.2 3.6 2.1 4.6 0.8 2.1 9.4 1.8 2.3 29.5 13.5 0.7 4.0 1.3 1.0 4.4 0.9 24.2 0.5 1.7 0.7 1.0 0.0 0.6 1.2 0.4 1.6 0.0 0.3 3.5 0.4 3.2 0.4 0.0 0.3 1.4 0.8 0.0 1.7 0.0 1.1 0.0 1.9 0.0 0.0 0.4 0.5 1.0 0.0 0.5 0.0 0.6 0.0 1.1 0.5 0.7 0.3 0.1 0.2 1.2 0.0 2.8 2.9 0.6 0.0 0.0 3.6 3.6 6.9 3.1 0.0 0.0 0.0 0.2 0.0 1.1 1.2 0.7 0.3 0.0 0.2 1.3 0.5 1.2 0.3 0.8 1.3 2.3 0.7 0.7 0.7 0.2 0.5 0.3 1.1 0.4 0.1 0.6 1.4 0.6 2.5 0.0 0.1 0.5 0.5 0.2 13.6 15.2 5.9 14.2 11.9 12.5 15.1 15.7 10.9 9.4 13.5 24.2 0.3 0.0 1.7 61.0 0.1 0.3 4.2 8.7 2.8 1.3 1.3 3.0 41.0 0.0 8.9 5.5 8.4 0.1 0.0 0.1 54.8 3.4 310.9 67.0 3.1 1.2 6.6 0.0 124.3 7.1 0.1 1.2 0.0 1.9 0.0 0.7 0.7 3.9 0.1 0.0 174.9 0.3 10.2 0.6 0.3 369.8 3.7 0.4 0.0 11.2 0.0 6.0 0.0 59.3 20.0 1.6 1.2 2.6 0.1 3.2 0.0 6.3 118.4 8.1 0.0 1.1 2.2 53.4 6.1 1.1 0.3 0.3 0.3 2.9 0.4 2.7 PAGE5 "CT16.1, CT16.2, PAGE-5" ENSG00000158639 "PAGE family member 5" Q96GU1 X 55220346-55224108 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "testis: 26.5" "Group enriched" "Detected in some" 7 "Spermatocytes: 131.0;Spermatogonia: 158.8" "Group enriched" "Detected in many" 6 "liver cancer: 5.4;melanoma: 11.8;testis cancer: 6.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 1.9" "Lineage enriched" "Detected in single" 13 "T-cells: 1.9" "Group enriched" "Detected in some" 170 "Karpas-707: 437.8;U-266/84: 992.7" "HPA052619, HPA055869" Supported Approved Mitochondria NA NA "Cluster 13: T-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Mitochondria "HPA052619: AB_2681887, HPA055869: " "unprognostic (4.03e-1)" "unprognostic (4.51e-2)" "unprognostic (7.86e-4)" "unprognostic (1.39e-2)" "unprognostic (7.21e-2)" "unprognostic (1.06e-4)" "unprognostic (2.29e-1)" "unprognostic (1.94e-1)" "unprognostic (3.44e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.3 26.5 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.7 0.1 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 437.8 0.0 0.0 1.2 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.4 0.0 0.0 0.5 1.3 1.6 4.2 992.7 0.5 0.1 0.0 0.7 0.0 0.0 0.0 0.3 0.0 1.9 0.1 1.6 0.7 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.1 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 19.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.3 11.9 2.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.5 0.1 0.0 6.6 0.0 0.1 131.0 158.8 0.0 0.1 0.0 1.4 0.0 0.0 0.1 PAIP2B KIAA1155 ENSG00000124374 "Poly(A) binding protein interacting protein 2B" Q9ULR5 2 71182738-71227103 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 181.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 86.0;Early spermatids: 95.1;Hepatocytes: 67.1;Proximal tubular cells: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 15.8;SCLC-21H: 23.1" "Low region specificity" "Detected in all" "HPA046784, HPA072371" Approved Approved Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol "HPA046784: AB_2679804, HPA072371: AB_2686514" "unprognostic (8.70e-2)" "unprognostic (8.20e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (8.17e-5)" "unprognostic (4.56e-2)" "unprognostic (1.34e-1)" "unprognostic (9.67e-3)" "unprognostic (1.51e-2)" "unprognostic (3.61e-1)" "unprognostic (1.78e-1)" "unprognostic (5.25e-2)" "unprognostic (2.76e-1)" "prognostic favorable (6.96e-12)" "unprognostic (1.63e-2)" "unprognostic (3.87e-1)" "unprognostic (1.21e-2)" "unprognostic (4.61e-2)" 2.4 1.6 131.5 1.8 159.1 1.3 4.5 108.3 176.8 3.1 66.3 3.8 3.7 2.9 1.8 6.1 7.2 1.1 23.0 94.7 116.5 10.3 18.1 2.7 2.1 134.9 136.6 11.5 54.2 6.0 2.2 0.6 143.0 4.8 3.7 27.7 37.9 3.5 48.5 16.4 2.7 1.7 132.8 2.2 10.5 2.2 130.3 2.4 11.6 26.7 4.6 2.8 4.0 181.5 2.5 0.6 1.0 3.6 0.4 0.5 4.4 0.3 0.1 0.3 0.2 0.9 1.0 3.2 0.6 0.0 2.4 2.0 6.1 3.7 1.2 1.7 5.0 3.1 0.4 0.1 1.6 0.8 0.2 0.6 3.3 0.2 3.6 0.9 0.6 7.2 5.5 3.0 0.2 3.2 1.0 1.7 2.6 5.8 2.3 0.0 10.5 15.8 1.9 1.7 23.1 1.3 2.6 1.7 1.1 5.5 7.5 0.2 0.1 0.3 1.9 1.9 1.0 6.1 5.5 3.9 0.2 1.1 0.5 0.5 0.3 0.5 1.0 0.4 1.2 2.5 1.3 1.0 0.4 2.6 2.1 1.9 0.2 0.8 0.4 2.3 0.6 0.6 131.5 159.1 108.3 176.8 94.7 116.5 134.9 136.6 143.0 132.8 130.3 181.5 3.3 3.2 4.5 5.2 9.9 7.8 7.0 4.0 5.7 11.3 14.8 8.8 86.0 12.8 2.7 7.3 6.2 3.2 13.2 2.7 21.5 4.9 95.1 18.4 3.9 3.9 41.5 15.6 4.2 41.3 9.2 4.7 11.2 17.5 1.3 7.5 7.1 67.1 1.9 6.7 4.6 6.3 14.2 3.2 1.6 30.0 5.3 2.6 14.2 2.8 2.4 12.3 4.1 2.5 31.9 10.4 4.0 5.3 29.9 9.4 1.3 56.9 15.5 43.3 0.0 9.3 4.0 32.9 7.7 17.3 20.0 6.3 4.7 4.3 8.1 6.0 PALM "KIAA0270, PALM1" ENSG00000099864 Paralemmin O75781 19 708935-748329 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 257.8" "Cell type enhanced" "Detected in many" "Astrocytes: 85.2;Distal tubular cells: 52.8;Hepatic stellate cells: 63.1;Leydig cells: 48.4;Muller glia cells: 92.8;Proximal tubular cells: 57.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "non-classical monocyte: 1.9" "Lineage enriched" "Detected in single" 19 "monocytes: 1.9" "Cell line enhanced" "Detected in many" "AN3-CA: 16.6;EFO-21: 20.7;REH: 34.3;SH-SY5Y: 28.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041713, HPA049578" Approved Enhanced "Nucleoplasm,Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Plasma membrane" "HPA041713: AB_10794305, HPA049578: AB_2680822" "unprognostic (9.08e-3)" "unprognostic (2.97e-2)" "unprognostic (2.11e-2)" "unprognostic (3.53e-3)" "unprognostic (1.61e-1)" "unprognostic (3.77e-2)" "unprognostic (1.42e-1)" "unprognostic (8.39e-2)" "unprognostic (7.62e-2)" "unprognostic (1.36e-2)" "prognostic favorable (9.81e-4)" "unprognostic (2.74e-2)" "prognostic favorable (5.44e-4)" "unprognostic (1.24e-2)" "unprognostic (1.13e-1)" "unprognostic (1.55e-2)" "unprognostic (6.00e-2)" 89.0 23.1 158.4 2.0 140.7 0.7 66.0 86.1 257.8 60.3 54.5 54.4 7.4 43.3 3.3 14.4 47.0 2.8 41.1 165.1 97.0 52.7 7.3 30.0 0.6 106.4 103.6 65.7 5.8 1.2 62.5 6.6 96.9 42.6 0.6 4.6 12.9 8.3 9.6 33.4 20.8 2.4 95.0 23.4 18.0 19.6 112.1 0.6 21.0 1.7 0.2 29.4 41.8 110.5 0.0 7.6 14.6 16.6 0.6 0.2 2.2 0.9 0.0 1.0 0.2 1.9 0.1 0.0 20.7 0.0 0.0 2.7 8.0 0.0 0.4 0.0 14.1 0.0 4.3 9.3 9.4 0.0 0.3 3.0 0.0 0.9 0.0 0.4 0.4 1.6 4.6 0.1 1.1 15.9 1.1 9.4 5.9 1.0 3.2 34.3 0.0 0.2 0.6 0.0 1.7 28.0 7.5 0.1 0.2 4.6 1.8 4.5 0.0 0.0 13.4 16.1 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 158.4 140.7 86.1 257.8 165.1 97.0 106.4 103.6 96.9 95.0 112.1 110.5 27.2 0.0 1.7 85.2 2.7 7.1 7.2 6.3 1.8 11.4 5.7 5.3 5.8 1.5 4.9 5.5 12.5 0.9 0.2 1.3 52.8 1.4 1.4 3.8 27.0 25.6 0.0 1.3 26.9 0.2 7.2 37.6 1.1 5.9 0.0 1.4 63.1 0.4 1.0 25.2 15.1 0.1 12.2 2.4 5.4 6.6 48.4 1.1 17.8 10.3 0.1 92.8 0.0 16.6 9.8 0.2 1.4 45.1 0.1 10.1 7.2 57.9 0.5 5.7 0.0 2.3 14.1 0.8 7.3 1.1 7.0 1.9 1.1 0.1 0.4 7.2 PALMD "C1orf11, FLJ20271, PALML" ENSG00000099260 Palmdelphin Q9NP74 1 99646113-99694541 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 130.8" "Cell type enhanced" "Detected in many" "Adipocytes: 537.2;Cardiomyocytes: 157.6;Endothelial cells: 219.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 155.2;LHCN-M2: 49.5;TIME: 220.5;U-87 MG: 92.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017959, HPA030549" Supported Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Actin filaments" "Plasma membrane, Focal adhesion sites" "HPA017959: AB_1854949, HPA030549: AB_2673518" "unprognostic (1.48e-2)" "unprognostic (1.15e-2)" "unprognostic (2.05e-2)" "prognostic favorable (9.42e-4)" "unprognostic (7.67e-2)" "prognostic favorable (5.90e-5)" "unprognostic (1.54e-2)" "unprognostic (2.10e-1)" "unprognostic (3.93e-2)" "unprognostic (1.64e-1)" "unprognostic (8.32e-2)" "unprognostic (6.18e-2)" "unprognostic (5.19e-2)" "unprognostic (1.63e-2)" "unprognostic (1.88e-1)" "unprognostic (2.70e-1)" "unprognostic (8.08e-2)" 130.8 43.0 14.6 7.1 11.7 0.0 77.6 10.5 15.3 27.4 45.8 9.5 3.4 33.0 6.1 38.2 22.8 14.6 91.2 13.7 12.7 11.0 57.1 28.4 3.9 12.0 11.8 18.8 4.9 9.2 10.5 43.2 11.5 18.0 6.5 7.5 71.0 7.9 112.6 48.9 8.6 31.4 11.1 6.3 6.1 11.0 14.1 8.0 7.2 66.2 8.6 14.5 15.9 10.4 0.0 0.3 0.4 0.2 7.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 39.2 2.5 0.6 10.8 0.0 0.5 0.1 0.1 0.1 0.0 18.6 26.4 0.0 0.0 0.1 3.9 2.0 0.0 0.0 4.3 155.2 0.0 22.7 0.0 49.5 0.6 0.0 0.0 0.0 1.6 6.8 0.0 38.2 0.1 0.0 8.0 0.9 0.5 0.0 9.9 0.0 1.0 2.3 0.0 220.5 0.0 0.4 16.8 0.0 0.0 0.0 0.1 92.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 11.7 10.5 15.3 13.7 12.7 12.0 11.8 11.5 11.1 14.1 10.4 537.2 6.4 5.6 0.3 0.5 38.5 11.4 49.6 22.2 2.0 20.0 31.8 157.6 32.9 35.9 3.7 0.0 0.4 1.6 0.1 5.9 8.1 74.9 78.7 71.9 219.4 1.8 2.7 1.4 0.2 0.3 19.2 2.0 17.7 1.3 0.0 96.0 57.3 0.6 3.3 1.8 0.0 14.2 2.2 5.5 12.2 9.3 1.7 24.9 73.1 0.0 55.0 0.0 0.5 0.2 4.1 0.0 24.0 0.0 5.9 0.0 0.4 111.5 3.3 0.0 91.3 12.7 0.5 0.6 27.5 46.5 0.3 1.4 110.1 0.1 3.3 PAMR1 "DKFZP586H2123, RAMP" ENSG00000149090 "Peptidase domain containing associated with muscle regeneration 1" Q6UXH9 11 35431823-35530300 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 7 "Astrocytes: 380.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 86.9;ASC TERT1: 354.7;BJ hTERT+: 357.7;fHDF/TERT166: 86.7;HSkMC: 123.1;U-87 MG: 82.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted - unknown location" NA NA 5600000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (3.38e-1)" "unprognostic (1.07e-2)" "unprognostic (1.67e-1)" "unprognostic (1.00e-3)" "unprognostic (6.50e-3)" "unprognostic (1.01e-1)" "unprognostic (2.07e-2)" "unprognostic (6.92e-2)" "unprognostic (3.32e-2)" "unprognostic (4.07e-2)" "unprognostic (1.91e-2)" "unprognostic (1.36e-2)" "prognostic unfavorable (5.08e-5)" "prognostic unfavorable (6.29e-4)" "unprognostic (2.08e-1)" "unprognostic (9.98e-2)" "unprognostic (8.25e-2)" 32.8 14.9 25.1 0.6 27.4 0.0 15.4 22.0 23.2 59.9 13.9 14.9 4.5 58.2 18.3 10.0 22.6 20.3 23.2 22.5 26.2 7.1 12.6 5.9 1.3 37.9 35.9 3.4 5.3 1.7 6.4 55.9 32.4 21.2 6.6 0.9 5.7 17.9 2.7 19.8 9.9 14.9 46.1 5.7 5.4 0.2 34.1 2.8 7.0 9.0 1.7 28.0 41.3 38.8 0.0 0.0 0.1 0.0 86.9 354.7 0.1 42.8 357.7 4.9 8.3 32.7 0.0 0.0 0.0 86.7 0.1 0.1 0.0 0.0 3.3 0.0 0.8 0.0 0.0 0.0 50.1 0.0 0.0 123.1 1.8 9.7 1.3 0.1 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.7 0.0 0.2 0.0 0.2 0.2 0.0 8.4 0.1 0.0 0.0 0.0 0.0 14.3 2.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.1 0.0 82.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.1 27.4 22.0 23.2 22.5 26.2 37.9 35.9 32.4 46.1 34.1 38.8 2.5 0.0 0.0 380.3 0.0 19.1 1.4 14.8 1.2 0.1 0.7 19.7 1.3 0.0 2.4 1.8 0.0 2.2 0.0 0.0 0.0 1.4 0.1 4.5 26.2 1.1 0.0 0.0 13.1 0.0 1.4 50.2 1.1 0.8 0.0 0.6 0.0 0.0 2.0 0.0 8.2 0.2 0.0 0.0 5.5 0.1 0.3 0.5 1.8 28.1 0.6 0.0 0.0 9.5 1.4 0.1 0.0 0.0 0.0 0.4 0.2 0.0 1.8 0.2 0.0 1.6 5.8 0.0 0.2 0.1 9.2 3.4 0.6 0.2 0.0 0.2 PAQR7 "MPRA, mSR" ENSG00000182749 "Progestin and adipoQ receptor family member 7" Q86WK9 1 25861484-25875708 "Predicted membrane proteins" "Differentiation, Oogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Late spermatids: 1939.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 75.5;HaCaT: 62.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046936 Approved Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA046936: AB_2679869" "unprognostic (1.12e-1)" "unprognostic (2.08e-2)" "unprognostic (8.03e-2)" "unprognostic (4.54e-3)" "unprognostic (1.32e-1)" "unprognostic (3.41e-1)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.47e-1)" "unprognostic (4.59e-3)" "unprognostic (7.79e-2)" "unprognostic (1.29e-1)" "unprognostic (1.31e-1)" "prognostic favorable (1.05e-5)" "unprognostic (1.60e-2)" "unprognostic (2.98e-2)" "unprognostic (1.15e-2)" "unprognostic (1.54e-2)" 5.5 23.9 8.5 4.4 8.4 5.1 5.2 7.5 8.6 11.9 10.0 6.4 20.9 11.1 28.2 17.7 20.0 7.8 3.3 7.9 10.1 35.3 7.4 5.6 4.3 9.6 10.2 35.3 6.6 13.7 6.7 21.4 9.4 7.9 2.9 1.5 5.3 24.3 3.0 31.4 18.9 9.5 9.2 10.2 8.1 46.2 10.6 3.5 5.1 1.9 4.9 13.6 13.5 9.4 30.7 6.0 5.8 18.9 7.1 14.8 20.4 19.9 17.5 19.2 17.0 9.8 75.5 0.3 13.6 19.2 6.3 62.6 3.2 33.0 11.4 12.1 3.4 25.6 8.4 12.1 12.0 0.4 3.1 14.9 43.3 13.7 10.2 16.9 7.5 2.8 2.8 2.1 14.4 7.0 0.2 1.9 9.3 3.1 10.3 2.1 0.6 3.8 39.3 22.9 3.1 11.5 32.1 40.7 14.8 7.9 11.6 4.6 8.1 3.1 9.7 10.2 5.4 0.4 0.4 1.3 14.5 0.7 6.6 5.4 7.3 15.7 1.4 13.9 1.4 4.0 0.8 1.0 7.6 1.7 1.3 1.9 3.7 3.4 17.5 0.8 0.2 1.4 8.5 8.4 7.5 8.6 7.9 10.1 9.6 10.2 9.4 9.2 10.6 9.4 4.9 0.0 3.1 11.4 2.2 18.1 4.3 4.6 4.6 2.1 9.4 9.5 1.9 17.2 5.1 77.3 0.0 52.8 1.3 0.7 21.5 5.6 350.9 23.4 11.5 5.9 4.8 0.0 11.9 13.9 12.3 7.8 0.5 9.0 7.0 4.6 10.4 5.5 11.0 3.3 11.2 2.2 0.0 10.3 14.9 1939.3 19.9 7.8 21.4 7.5 7.6 1.6 0.0 8.5 4.0 6.4 3.0 15.1 0.7 3.1 27.9 70.2 8.6 0.6 13.1 4.3 4.7 11.6 10.0 4.7 13.1 35.7 1.6 5.8 3.7 3.1 PATZ1 "dJ400N23, MAZR, PATZ, RIAZ, ZBTB19, ZNF278, ZSG" ENSG00000100105 "POZ/BTB and AT hook containing zinc finger 1" Q9HBE1 22 31325804-31346346 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047893, HPA048315" Approved Supported Nucleoplasm No No "Cluster 13: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "HPA047893: AB_2680201, HPA048315: AB_2680353" "unprognostic (3.25e-1)" "unprognostic (8.72e-2)" "unprognostic (1.77e-1)" "unprognostic (2.88e-3)" "prognostic favorable (1.06e-4)" "unprognostic (1.77e-1)" "unprognostic (8.34e-3)" "prognostic favorable (8.71e-5)" "unprognostic (1.14e-1)" "unprognostic (1.41e-2)" "unprognostic (1.99e-3)" "unprognostic (1.76e-1)" "prognostic favorable (8.54e-8)" "unprognostic (9.22e-2)" "unprognostic (2.15e-1)" "unprognostic (1.51e-1)" "prognostic favorable (7.79e-6)" 10.2 10.5 16.0 11.4 18.1 15.8 12.1 16.4 16.1 14.5 11.1 14.8 9.9 18.7 14.2 6.1 22.2 9.3 10.8 14.7 16.0 11.6 11.8 11.2 20.3 18.4 16.7 27.3 13.5 21.0 10.5 9.3 17.6 13.1 6.9 14.9 18.7 17.0 10.5 7.9 12.7 12.2 17.1 15.7 11.1 8.1 16.4 24.0 19.3 8.5 14.8 15.7 9.7 20.4 19.0 23.3 46.7 27.7 12.1 11.1 24.5 5.7 14.2 22.6 20.6 16.5 17.7 40.1 20.1 10.6 7.9 14.5 32.0 17.3 11.5 23.7 29.5 16.9 16.7 33.8 19.7 57.4 21.9 17.4 20.5 14.4 16.0 17.8 18.0 19.4 7.3 15.7 14.6 57.7 37.1 39.3 31.4 34.4 27.1 61.9 19.9 13.3 15.3 39.4 60.8 48.7 14.2 17.1 31.4 15.4 33.8 36.2 12.8 15.1 28.3 9.5 19.5 20.3 14.4 36.5 6.3 7.5 26.3 0.0 1.0 2.8 1.8 0.6 1.8 2.5 1.3 2.3 1.4 1.8 2.9 2.2 0.4 2.1 0.3 4.0 2.2 1.2 16.0 18.1 16.4 16.1 14.7 16.0 18.4 16.7 17.6 17.1 16.4 20.4 6.6 3.2 14.9 11.4 12.8 1.7 7.1 7.6 8.0 16.8 22.0 16.0 13.7 17.2 11.7 20.2 8.4 5.2 17.0 3.3 19.6 14.3 0.6 14.9 8.8 7.6 20.4 8.0 2.4 6.2 2.0 6.4 5.6 16.7 6.3 19.3 7.1 16.2 9.4 21.9 5.0 9.7 20.3 8.1 2.6 1.7 9.6 6.6 3.6 7.5 7.7 14.4 12.3 11.1 8.8 6.4 6.0 8.6 5.5 7.4 5.0 7.1 10.5 14.3 6.6 7.1 8.5 0.7 8.1 2.3 1.6 0.8 10.4 8.4 11.8 7.3 PBX1 ENSG00000185630 "PBX homeobox 1" P40424 1 164555584-164899296 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Sexual differentiation, Steroidogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 382.3;Excitatory neurons: 475.9;Inhibitory neurons: 405.0;Oligodendrocyte precursor cells: 327.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 93.0;NTERA-2: 111.5;SK-BR-3: 186.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003505, HPA003881, CAB018768" Supported Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear bodies, Cytosol" "CAB018768: AB_675783, HPA003505: AB_1855019, HPA003881: AB_1855020" "unprognostic (2.26e-2)" "unprognostic (1.95e-1)" "unprognostic (9.09e-2)" "unprognostic (2.14e-2)" "unprognostic (5.21e-3)" "unprognostic (6.94e-3)" "unprognostic (5.95e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "unprognostic (2.24e-3)" "unprognostic (2.30e-1)" "unprognostic (8.81e-2)" "unprognostic (1.34e-2)" "unprognostic (2.13e-1)" "unprognostic (5.07e-2)" "unprognostic (1.11e-1)" "unprognostic (1.25e-1)" 24.3 32.1 16.5 11.8 22.3 3.1 36.1 10.7 18.0 88.3 1.9 52.3 22.4 136.8 21.6 30.1 74.6 37.6 24.0 15.3 14.1 29.4 7.7 20.7 4.5 8.8 32.7 52.1 48.1 29.5 14.3 19.5 6.7 38.0 19.8 17.1 43.8 53.8 36.3 10.2 19.9 125.2 13.7 10.2 21.9 6.8 12.6 10.9 35.1 26.5 8.1 40.2 41.5 12.1 2.9 74.4 82.4 19.1 50.8 23.3 3.4 25.2 20.9 8.4 6.1 14.2 11.8 0.0 5.5 47.8 4.3 22.8 31.7 8.1 3.6 3.1 31.3 93.0 56.5 0.3 34.7 0.0 22.2 24.4 0.0 5.4 2.1 19.2 0.3 0.0 0.2 0.0 2.2 47.1 0.2 0.6 111.5 3.8 4.5 0.0 21.6 27.0 6.3 44.1 2.5 39.6 27.8 186.1 0.1 71.4 73.2 0.0 0.5 3.7 8.6 24.2 8.1 8.5 61.2 0.1 0.4 0.2 0.4 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 16.5 22.3 10.7 18.0 15.3 14.1 8.8 32.7 6.7 13.7 12.6 12.1 28.6 22.4 18.6 382.3 2.8 22.8 115.0 39.8 70.6 39.9 129.9 87.8 50.0 98.7 25.3 33.1 110.5 101.3 1.5 29.2 33.2 47.9 91.3 47.7 144.3 47.0 90.9 30.3 475.9 68.7 7.3 126.7 32.1 38.5 71.7 57.6 68.9 18.7 9.7 5.0 405.0 38.2 50.8 1.9 17.5 124.4 63.6 12.1 16.0 125.5 1.6 33.5 1.0 327.2 227.4 31.7 72.5 103.8 2.8 41.5 40.4 57.9 37.3 30.6 39.5 142.0 70.9 2.3 17.5 83.6 28.1 104.7 7.6 168.0 43.7 75.9 PCCA ENSG00000175198 "Propionyl-CoA carboxylase subunit alpha" P05165 13 100089015-100530437 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 218.2" "Cell type enhanced" "Detected in all" "Astrocytes: 152.8;Excitatory neurons: 152.8;Inhibitory neurons: 166.5;Microglial cells: 217.4;Oligodendrocyte precursor cells: 200.6;Oligodendrocytes: 182.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 167.0;SCLC-21H: 91.1;U-937: 131.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041716, HPA047792" Enhanced Supported Mitochondria NA NA 290000 "Cluster 27: Non-specific - Gene expression" "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" Mitochondria "HPA041716: AB_2677635, HPA047792: AB_2680156" "unprognostic (1.18e-1)" "unprognostic (2.13e-1)" "unprognostic (1.97e-2)" "unprognostic (4.71e-2)" "unprognostic (1.11e-2)" "unprognostic (1.71e-2)" "unprognostic (1.55e-1)" "unprognostic (5.90e-3)" "unprognostic (2.41e-1)" "unprognostic (1.55e-1)" "unprognostic (6.14e-2)" "unprognostic (1.42e-1)" "prognostic favorable (0.00e+0)" "unprognostic (7.08e-2)" "unprognostic (1.12e-1)" "unprognostic (1.18e-1)" "unprognostic (9.32e-2)" 35.4 56.3 29.0 12.4 29.8 6.2 25.8 55.5 34.6 22.3 44.4 37.5 13.2 14.9 218.2 19.4 17.4 11.6 35.4 28.6 26.3 111.7 104.3 12.0 8.0 28.9 27.4 19.9 27.6 25.7 12.3 21.3 31.1 25.9 27.6 25.2 26.9 16.9 17.6 18.6 18.0 13.7 30.3 17.2 40.9 9.2 33.9 11.4 20.4 27.2 6.4 21.3 17.5 38.7 10.6 18.5 29.8 9.9 27.9 24.2 16.6 10.2 15.4 9.5 9.0 23.0 13.9 0.8 15.2 10.1 12.0 11.8 9.1 14.1 15.6 17.5 10.1 24.6 12.7 49.7 15.4 1.2 11.3 22.4 15.2 8.8 14.6 23.0 19.6 13.0 9.8 13.4 17.1 11.6 2.6 54.8 18.6 37.2 8.1 21.4 12.9 17.3 167.0 20.5 91.1 10.9 7.0 38.4 17.9 31.9 27.9 43.1 14.3 9.6 8.0 6.7 7.3 13.1 12.9 0.4 18.4 131.6 6.9 1.6 9.1 1.7 4.5 11.2 5.9 3.6 2.8 4.2 13.5 2.3 3.9 4.9 1.1 8.7 12.3 1.1 6.5 5.2 29.0 29.8 55.5 34.6 28.6 26.3 28.9 27.4 31.1 30.3 33.9 38.7 11.3 3.2 8.7 152.8 6.6 1.9 29.1 12.7 8.6 15.5 13.5 8.8 10.5 52.9 14.8 20.2 29.2 25.7 4.3 20.7 99.7 19.7 17.6 76.5 22.4 12.0 3.6 3.4 152.8 8.4 6.9 12.9 12.2 72.9 14.0 20.7 12.1 48.8 11.8 28.6 166.5 12.4 12.2 14.2 2.2 12.0 8.7 8.2 5.4 217.4 6.0 11.5 10.3 200.6 182.5 5.8 17.5 13.5 9.4 11.2 13.2 86.9 13.2 31.7 13.1 12.3 10.1 7.2 6.2 10.6 3.8 30.2 6.4 17.6 27.6 19.2 PCDH17 "PCDH68, PCH68" ENSG00000118946 "Protocadherin 17" O14917 13 57631744-57729311 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.9;lymphoid tissue: 25.1" "Group enriched" "Detected in many" 4 "Adipocytes: 57.6;Astrocytes: 77.1;Early spermatids: 60.7;Endothelial cells: 126.7;Excitatory neurons: 125.2;Hepatic stellate cells: 79.6;Inhibitory neurons: 67.9;Oligodendrocyte precursor cells: 193.0;Oligodendrocytes: 101.1;Spermatocytes: 68.3" "Cancer enhanced" "Detected in many" "glioma: 9.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.7;HEK 293: 9.3;U-87 MG: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026817 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA 690000 "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" "Plasma membrane" "HPA026817: AB_1855044" "unprognostic (1.02e-2)" "unprognostic (2.39e-1)" "unprognostic (1.19e-1)" "unprognostic (6.52e-2)" "unprognostic (6.98e-3)" "unprognostic (1.95e-2)" "unprognostic (8.26e-4)" "unprognostic (3.56e-1)" "unprognostic (2.38e-2)" "unprognostic (2.82e-1)" "unprognostic (5.40e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (1.07e-2)" "unprognostic (1.80e-1)" "unprognostic (2.35e-1)" "unprognostic (3.40e-2)" 1.6 1.8 15.8 1.8 20.6 0.0 0.8 7.9 13.9 2.2 0.1 1.2 0.8 2.1 0.8 0.6 2.0 3.2 2.2 11.7 25.5 1.9 1.0 14.0 0.6 9.3 15.8 0.5 6.0 1.6 0.9 4.4 11.4 1.0 0.8 1.0 0.7 0.7 1.7 0.3 0.8 2.1 7.6 25.1 1.5 8.8 27.9 0.2 2.9 1.3 0.5 2.7 0.8 10.5 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 2.5 0.0 0.0 0.0 1.7 0.0 0.0 0.0 9.3 0.4 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.3 0.0 2.3 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.4 1.2 0.0 1.0 0.0 0.0 0.0 5.3 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 20.6 7.9 13.9 11.7 25.5 9.3 15.8 11.4 7.6 27.9 10.5 57.6 0.0 4.3 77.1 0.1 2.7 0.1 0.0 1.2 7.1 0.4 0.6 6.0 1.5 8.6 1.8 0.0 0.2 0.5 0.1 0.0 11.1 60.7 2.6 2.0 126.7 0.0 0.0 125.2 8.3 0.1 11.7 0.0 19.8 0.0 20.5 79.6 0.3 0.6 0.0 67.9 0.0 0.0 1.9 2.5 19.0 1.8 0.5 10.6 12.2 1.6 2.3 0.0 193.0 101.1 1.3 0.0 1.2 1.2 0.3 0.0 0.0 5.1 0.0 6.6 1.9 10.7 68.3 10.6 0.4 1.0 0.0 1.1 1.6 0.0 0.4 PCSK6 "PACE4, SPC4" ENSG00000140479 "Proprotein convertase subtilisin/kexin type 6" P29122 15 101289784-101525202 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 153.6;liver: 160.0;lymphoid tissue: 81.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 231.6;Horizontal cells: 196.9;Oligodendrocytes: 561.9;Theca cells: 106.5" "Cancer enhanced" "Detected in many" "liver cancer: 8.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 47.2;CACO-2: 35.7;HEK 293: 60.3;Hep G2: 53.8;OE19: 65.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004774 Uncertain "Secreted to extracellular matrix" NA NA 480000 "Cluster 15: NK-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA004774: AB_1079583" "prognostic favorable (9.99e-4)" "unprognostic (1.09e-1)" "unprognostic (4.37e-2)" "unprognostic (2.46e-2)" "unprognostic (9.83e-2)" "unprognostic (8.14e-2)" "unprognostic (2.20e-3)" "unprognostic (8.56e-2)" "unprognostic (2.16e-1)" "unprognostic (2.39e-2)" "unprognostic (3.85e-3)" "unprognostic (2.01e-1)" "prognostic unfavorable (7.06e-7)" "unprognostic (2.02e-1)" "unprognostic (1.87e-1)" "unprognostic (1.15e-1)" "unprognostic (1.03e-2)" 5.3 2.2 17.5 3.0 67.3 1.1 11.2 57.8 37.0 2.2 4.2 16.5 6.8 2.0 3.3 9.0 2.8 3.1 20.0 19.3 34.1 3.2 160.0 3.6 2.5 113.0 64.5 6.1 2.6 0.6 5.1 32.0 95.6 3.1 14.8 7.6 2.8 0.6 11.4 10.1 10.1 3.6 42.9 81.4 9.8 13.0 54.0 20.9 2.2 16.3 1.8 3.7 2.6 153.6 19.7 14.6 2.6 0.9 0.2 0.4 47.2 0.7 2.5 0.0 0.1 35.7 8.3 0.4 2.4 0.6 1.1 11.4 12.5 1.5 0.0 2.8 60.3 33.5 8.4 53.8 1.6 4.5 0.4 0.3 7.5 0.2 0.2 0.2 0.1 4.3 24.5 0.2 0.0 8.8 0.1 4.7 9.3 65.9 6.5 0.2 0.4 4.4 4.4 25.4 7.3 8.6 26.2 1.5 9.1 6.6 2.2 21.9 0.2 0.3 1.2 0.3 0.2 0.5 0.6 0.7 0.2 0.6 7.3 0.8 0.2 0.9 0.2 0.4 0.3 0.5 0.4 0.2 0.1 1.0 0.6 0.5 0.4 3.3 1.3 0.4 0.1 1.2 17.5 67.3 57.8 37.0 19.3 34.1 113.0 64.5 95.6 42.9 54.0 153.6 1.7 3.2 0.6 2.9 1.3 0.4 0.3 0.9 0.6 1.7 15.4 6.6 2.0 8.6 1.4 1.8 20.9 6.7 0.6 22.6 0.0 0.6 1.6 4.7 21.6 4.9 0.0 3.2 19.4 0.8 24.3 15.5 1.5 6.9 0.0 4.2 12.5 231.6 1.4 196.9 30.8 3.7 0.0 5.2 1.1 2.4 10.5 1.7 0.0 5.6 1.0 1.7 3.1 25.6 561.9 7.3 8.2 0.0 0.0 1.7 2.3 0.1 1.2 1.6 0.0 2.0 1.0 4.7 2.4 0.9 0.1 3.3 1.0 106.5 8.5 0.2 PCTP STARD2 ENSG00000141179 "Phosphatidylcholine transfer protein" Q9UKL6 17 55751051-55842830 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 98.0" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 68.5;Hepatocytes: 72.8;Syncytiotrophoblasts: 67.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 241.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 94.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA022979 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Nucleoli" "HPA022979: AB_2671018" "unprognostic (1.14e-1)" "unprognostic (5.20e-2)" "unprognostic (4.27e-2)" "unprognostic (7.35e-2)" "unprognostic (3.37e-2)" "prognostic unfavorable (3.43e-6)" "unprognostic (9.35e-3)" "unprognostic (2.69e-1)" "unprognostic (2.07e-1)" "unprognostic (8.65e-2)" "unprognostic (6.63e-3)" "unprognostic (1.16e-1)" "unprognostic (5.36e-3)" "unprognostic (1.26e-1)" "unprognostic (4.93e-1)" "unprognostic (6.89e-3)" "unprognostic (3.04e-1)" 15.3 8.5 8.0 10.4 8.0 11.4 12.4 8.1 8.9 10.7 8.3 23.1 18.1 7.4 28.3 10.7 9.0 9.7 19.0 7.7 9.2 29.7 98.0 18.8 9.9 8.7 9.5 8.3 11.8 13.4 7.9 28.7 8.7 9.6 23.8 4.2 10.8 23.1 18.9 6.4 16.5 10.7 8.1 15.5 19.0 13.3 9.9 5.9 8.5 19.3 8.9 13.4 7.9 8.0 21.2 19.3 13.9 5.1 18.4 17.7 36.6 8.1 10.3 12.5 12.1 22.0 26.7 5.9 61.0 12.7 11.8 11.5 8.2 13.7 11.2 94.8 19.5 51.9 5.7 40.2 16.3 20.0 39.5 14.7 17.3 7.6 13.5 15.2 24.8 17.7 38.4 20.2 13.7 18.7 16.0 16.1 15.4 0.0 16.9 8.1 20.5 4.9 13.4 15.6 7.1 16.1 4.2 8.7 34.6 30.4 23.6 33.8 18.2 14.7 10.4 16.2 10.9 57.9 19.4 3.6 13.2 32.7 25.5 77.3 60.9 241.1 9.4 52.6 5.6 8.6 6.1 9.7 49.0 5.3 3.6 8.2 63.3 27.5 58.9 3.9 11.8 29.3 8.0 8.0 8.1 8.9 7.7 9.2 8.7 9.5 8.7 8.1 9.9 8.0 13.1 3.2 8.1 25.5 4.2 1.0 2.4 6.6 2.8 4.0 5.4 4.8 15.7 15.7 3.2 9.2 2.1 51.6 5.2 17.8 11.7 13.0 18.3 6.4 6.0 10.3 13.1 12.2 16.5 13.7 68.5 8.2 7.7 6.3 15.2 7.1 10.4 72.8 22.1 1.7 26.4 17.1 8.2 25.2 5.1 20.0 16.4 20.1 12.4 9.4 15.1 4.0 11.3 19.6 4.2 9.5 10.1 25.9 5.3 1.7 13.9 40.6 3.8 2.3 13.1 4.3 8.9 17.9 7.7 6.6 1.4 67.2 5.6 8.2 16.2 2.6 PCYOX1 "KIAA0908, PCL1" ENSG00000116005 "Prenylcysteine oxidase 1" Q9UHG3 2 70257386-70281185 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 599.4;Hepatocytes: 187.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 313.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035193 Approved "Intracellular and membrane" NA NA 510000000 "Cluster 44: Non-specific - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 11: Alveolar cells - Smell perception" "HPA035193: AB_10602017" "unprognostic (1.09e-1)" "unprognostic (1.72e-2)" "unprognostic (7.91e-2)" "unprognostic (1.15e-2)" "unprognostic (1.44e-1)" "unprognostic (2.05e-1)" "unprognostic (6.87e-2)" "unprognostic (6.28e-2)" "unprognostic (1.14e-1)" "unprognostic (1.80e-1)" "unprognostic (1.61e-1)" "unprognostic (4.38e-2)" "prognostic favorable (1.89e-4)" "unprognostic (3.26e-2)" "unprognostic (1.55e-1)" "unprognostic (1.13e-1)" "unprognostic (1.54e-2)" 78.5 33.5 15.4 12.7 15.7 3.7 34.4 12.1 18.4 56.5 29.3 26.9 24.9 39.9 33.6 38.8 35.6 31.7 37.7 14.7 27.8 92.6 103.5 56.2 14.6 16.5 22.0 39.6 20.6 66.0 17.9 29.0 24.9 44.3 23.6 30.7 70.1 46.6 92.1 33.0 24.5 40.8 14.6 15.6 22.1 14.2 28.4 11.1 60.0 50.4 14.2 25.7 25.2 13.2 38.8 54.9 43.2 48.6 313.2 160.0 37.9 64.8 59.4 35.4 26.5 86.5 33.6 4.0 27.3 89.2 58.2 62.2 31.7 50.2 40.5 22.1 26.9 14.9 41.0 75.7 31.4 14.1 12.7 154.9 54.1 47.4 13.3 93.9 42.6 14.2 27.0 27.8 50.7 23.6 10.7 22.8 26.1 55.9 23.1 19.6 90.2 34.5 50.1 42.8 11.3 24.1 97.8 47.7 45.5 61.0 39.1 18.2 53.4 59.2 32.7 52.9 34.2 22.9 55.1 5.1 71.3 19.3 22.1 16.3 6.5 6.8 8.3 5.4 10.4 3.7 8.0 6.7 5.9 2.8 10.8 9.2 4.1 6.1 6.0 7.4 7.8 6.5 15.4 15.7 12.1 18.4 14.7 27.8 16.5 22.0 24.9 14.6 28.4 13.2 37.3 599.4 77.5 16.0 12.2 21.3 23.1 43.9 29.6 48.7 46.0 31.8 81.1 40.0 49.9 53.3 43.8 43.4 12.1 30.7 7.9 26.7 1.7 18.4 65.9 33.4 8.5 12.0 24.7 10.2 36.0 81.9 22.4 36.2 10.1 20.9 39.7 187.8 22.1 57.2 36.8 21.0 36.7 17.4 9.2 3.9 89.2 14.3 24.9 23.4 8.6 90.3 11.3 21.6 18.0 13.9 21.0 120.7 26.2 27.0 47.7 69.0 25.0 36.9 72.3 65.5 63.7 14.7 32.2 40.8 28.3 22.0 14.5 56.2 26.5 18.4 PDE1A ENSG00000115252 "Phosphodiesterase 1A" P54750 2 182140036-182523192 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 46.6;thyroid gland: 45.8" "Cell type enhanced" "Detected in many" "Early spermatids: 396.3;Excitatory neurons: 764.9;Late spermatids: 592.1;Oligodendrocytes: 1178.0" "Cancer enhanced" "Detected in many" "thyroid cancer: 13.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ASC diff: 37.2;HHSteC: 22.0;HSkMC: 47.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022151 Approved Approved Nucleoplasm NA NA "Cluster 43: Testis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA022151: AB_1855118" "unprognostic (3.63e-1)" "unprognostic (7.21e-2)" "unprognostic (1.32e-1)" "unprognostic (8.61e-2)" "unprognostic (1.58e-1)" "unprognostic (3.02e-1)" "unprognostic (3.84e-1)" "unprognostic (3.82e-1)" "unprognostic (1.02e-1)" "unprognostic (5.38e-2)" "unprognostic (2.78e-1)" "unprognostic (2.86e-1)" "unprognostic (5.55e-3)" "unprognostic (2.50e-3)" "unprognostic (5.96e-2)" "unprognostic (1.37e-1)" "unprognostic (1.40e-3)" 10.5 4.4 16.9 4.6 20.4 0.0 5.0 35.5 23.4 17.2 2.4 11.8 3.0 8.7 8.0 5.6 10.3 23.7 15.6 30.3 8.4 46.6 3.9 3.6 2.1 2.6 4.2 10.9 2.1 2.2 2.7 1.2 5.4 3.6 6.7 1.4 2.0 5.4 2.8 2.2 5.7 12.9 3.7 3.1 5.6 35.6 16.5 8.4 45.8 5.0 0.9 9.7 9.8 18.2 0.0 0.2 3.9 0.0 37.2 3.1 0.1 0.3 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 4.7 0.0 5.1 0.0 22.0 0.0 0.0 47.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 7.5 1.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 3.7 0.0 5.4 0.1 0.1 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.9 20.4 35.5 23.4 30.3 8.4 2.6 4.2 5.4 3.7 16.5 18.2 6.7 0.0 2.6 15.3 0.0 1.3 2.0 0.1 8.0 20.0 0.3 0.3 5.9 1.5 1.4 27.6 0.0 0.1 0.0 0.1 185.9 0.5 396.3 0.3 0.4 8.9 0.0 0.0 764.9 0.4 0.0 18.6 0.0 0.8 0.0 0.1 5.0 0.0 0.1 0.0 185.8 1.0 0.0 0.0 1.8 592.1 14.9 0.4 0.0 30.0 0.0 0.3 0.0 18.1 1178.0 0.2 0.1 8.2 0.2 2.6 0.1 1.5 0.0 1.2 52.6 21.0 45.1 9.1 4.9 1.0 1.3 0.0 0.2 7.6 0.1 0.7 PDK4 ENSG00000004799 "Pyruvate dehydrogenase kinase 4" Q16654 7 95583499-95596516 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2300.1;tongue: 1216.5" "Cell type enhanced" "Detected in many" "Adipocytes: 681.3;Cardiomyocytes: 764.5;Kupffer cells: 464.0;Proximal enterocytes: 654.2;Smooth muscle cells: 489.7" "Cancer enhanced" "Detected in all" "renal cancer: 107.8;thyroid cancer: 89.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "classical monocyte: 32.5;eosinophil: 38.1;intermediate monocyte: 63.5;myeloid DC: 16.8;non-classical monocyte: 39.8" "Group enriched" "Detected in many" 12 "dendritic cells: 16.8;granulocytes: 38.1;monocytes: 63.5" "Cell line enriched" "Detected in many" 7 "ASC diff: 482.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056731 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA056731: AB_2683218" "unprognostic (3.18e-3)" "unprognostic (1.98e-1)" "unprognostic (1.52e-1)" "unprognostic (1.34e-1)" "unprognostic (5.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.00e-3)" "unprognostic (3.47e-1)" "unprognostic (6.38e-2)" "unprognostic (2.24e-3)" "unprognostic (1.87e-2)" "unprognostic (8.75e-2)" "unprognostic (2.41e-2)" "prognostic unfavorable (1.80e-4)" "unprognostic (9.15e-2)" "unprognostic (4.20e-2)" "unprognostic (1.12e-1)" 451.2 216.3 32.4 33.4 48.0 2.5 388.7 32.9 43.0 76.3 222.0 278.9 72.3 89.0 10.4 151.5 153.5 80.6 480.4 40.0 35.3 127.8 223.4 120.4 24.0 44.5 41.8 240.8 549.3 18.2 39.9 104.8 45.3 91.2 42.6 2.0 60.2 529.5 2300.1 91.9 163.3 62.2 34.8 99.0 173.1 13.3 39.8 13.8 72.1 1216.5 13.5 187.5 95.2 59.4 0.0 37.7 1.5 9.5 482.2 0.8 0.4 0.0 0.0 0.0 0.0 0.0 12.8 0.0 5.3 1.7 1.6 0.0 0.1 0.0 0.0 0.0 1.3 0.2 66.8 0.0 4.5 0.0 0.0 5.3 0.0 0.0 0.0 0.2 2.4 0.0 1.7 0.0 0.2 0.9 0.0 0.4 0.1 0.0 2.1 0.0 0.0 0.3 23.5 2.6 0.5 2.7 0.0 3.0 8.6 2.4 1.3 1.1 0.0 0.0 0.8 2.1 0.1 0.0 0.0 0.1 1.5 0.0 0.0 0.3 32.5 38.1 0.0 63.5 0.1 0.4 0.0 0.0 16.8 1.5 0.0 0.0 2.5 3.3 39.8 0.5 0.0 14.2 32.4 48.0 32.9 43.0 40.0 35.3 44.5 41.8 45.3 34.8 39.8 59.4 681.3 32.1 16.0 154.4 6.0 10.5 279.2 9.2 19.9 0.1 95.9 40.6 764.5 30.0 36.1 378.9 0.0 5.9 3.9 67.7 13.7 7.2 14.9 151.0 52.1 108.0 55.4 9.3 0.4 5.5 0.7 326.9 158.5 347.5 5.1 19.9 199.2 130.5 49.8 0.0 1.2 96.0 6.1 464.0 21.5 6.7 134.2 204.8 90.7 19.7 19.8 8.4 1.0 7.1 26.2 6.2 46.3 44.8 6.4 110.0 654.2 74.2 66.3 0.4 164.3 293.2 489.7 1.8 1.0 12.3 9.2 10.9 5.3 18.7 60.5 157.4 PDLIM2 ENSG00000120913 "PDZ and LIM domain 2" Q96JY6 8 22578279-22598025 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 793.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in all" "white matter: 429.2" "Low region specificity" "Detected in many" HPA003880 Approved Supported "Actin filaments,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Actin filaments, Focal adhesion sites" "HPA003880: AB_1855149" "unprognostic (1.04e-1)" "unprognostic (3.53e-2)" "unprognostic (1.80e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-3)" "unprognostic (9.33e-2)" "unprognostic (3.69e-2)" "unprognostic (4.55e-2)" "unprognostic (1.79e-2)" "unprognostic (1.22e-3)" "unprognostic (1.52e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (1.37e-7)" "unprognostic (6.14e-2)" "unprognostic (8.17e-2)" "unprognostic (3.47e-2)" "unprognostic (3.08e-3)" 66.0 31.6 40.6 31.9 42.2 23.7 51.0 51.0 56.6 85.1 42.6 86.9 60.9 80.2 9.8 131.4 56.0 52.8 51.4 36.9 43.9 77.7 59.4 88.8 54.4 56.6 52.9 49.6 53.7 9.8 35.3 40.5 59.4 45.5 11.2 2.0 48.6 30.9 201.9 153.1 64.3 23.2 49.9 232.0 38.8 12.2 49.9 20.4 27.4 60.9 24.4 57.5 91.7 54.8 90.3 54.5 36.2 63.9 69.9 118.5 40.9 139.1 102.4 97.6 98.5 62.4 14.7 36.9 38.4 126.4 18.1 44.7 20.5 95.0 19.0 0.1 14.1 11.6 35.2 46.1 88.2 13.0 85.9 127.2 11.6 48.2 13.2 76.8 54.2 20.2 3.3 23.4 67.4 46.5 16.7 15.4 29.8 37.8 5.5 13.3 6.9 3.9 17.3 18.3 11.3 26.9 29.1 78.1 128.7 21.3 27.5 25.8 68.2 105.7 108.6 127.9 64.8 0.4 0.8 12.5 109.0 51.3 79.6 78.2 48.0 162.3 47.0 64.4 42.2 25.0 35.5 46.9 38.4 27.6 23.8 35.4 101.6 28.1 63.8 24.7 40.7 34.6 40.6 42.2 51.0 56.6 36.9 43.9 56.6 52.9 59.4 49.9 49.9 54.8 85.8 76.9 13.1 5.5 45.0 95.1 12.9 48.1 39.9 3.0 34.0 42.5 10.2 18.6 34.2 18.4 0.0 73.1 70.9 92.0 15.6 24.9 1.0 8.8 94.0 48.7 1.2 10.5 3.2 26.1 115.1 98.9 7.7 13.8 27.3 25.7 86.4 49.4 59.0 3.3 2.3 12.6 20.3 59.1 73.8 3.4 132.0 37.9 48.0 8.4 42.5 33.1 122.6 7.1 3.9 93.2 126.1 218.2 6.8 52.7 217.6 146.3 5.2 3.6 59.2 27.1 108.3 0.7 6.3 39.7 100.7 793.0 71.6 21.0 15.0 30.6 PDSS2 "bA59I9.3, C6orf210, COQ1B" ENSG00000164494 "Decaprenyl diphosphate synthase subunit 2" Q86YH6 6 107152562-107459564 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isoprene biosynthesis, Ubiquinone biosynthesis" Transferase "Cancer-related genes, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 82.4;Oligodendrocyte precursor cells: 72.9;Oligodendrocytes: 74.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029685, HPA029686" Approved Supported Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA029685: AB_10600219, HPA029686: AB_10602309" "prognostic unfavorable (1.34e-5)" "unprognostic (1.44e-1)" "prognostic favorable (5.74e-5)" "unprognostic (5.76e-2)" "unprognostic (1.42e-1)" "unprognostic (3.30e-2)" "unprognostic (3.26e-2)" "unprognostic (1.42e-1)" "unprognostic (1.15e-1)" "unprognostic (1.18e-1)" "unprognostic (9.38e-2)" "unprognostic (2.19e-1)" "prognostic favorable (3.75e-7)" "unprognostic (2.25e-1)" "unprognostic (2.86e-1)" "unprognostic (1.29e-1)" "unprognostic (2.11e-2)" 7.9 17.9 4.6 6.3 5.2 9.0 8.1 6.1 5.7 9.2 6.8 12.4 9.3 6.8 6.5 8.6 8.6 8.7 13.9 4.6 5.2 21.6 27.1 8.0 7.6 4.9 4.7 9.1 8.4 13.2 8.5 6.8 5.0 14.6 13.2 6.0 15.3 7.4 12.5 6.3 9.6 8.5 4.7 6.7 9.6 7.7 5.3 8.1 13.3 13.7 7.1 7.6 6.1 6.1 7.6 10.0 8.3 13.2 14.2 18.0 19.2 13.1 16.5 12.4 11.8 10.0 10.8 14.4 11.7 14.7 13.1 10.2 20.3 16.5 16.7 9.1 9.8 14.4 11.4 16.9 15.0 18.5 11.1 13.5 19.1 19.5 15.3 10.8 13.1 16.5 20.7 19.0 12.2 9.3 5.4 19.7 5.3 17.3 12.7 9.7 7.4 11.7 15.2 10.2 8.2 7.1 9.0 15.4 19.7 9.0 12.7 22.3 8.3 8.8 5.2 12.4 11.4 5.3 6.8 11.3 16.3 27.4 16.3 3.2 5.1 2.8 3.7 5.9 5.9 4.7 3.8 4.7 7.0 5.5 5.0 4.8 0.6 3.6 9.9 3.3 5.5 3.4 4.6 5.2 6.1 5.7 4.6 5.2 4.9 4.7 5.0 4.7 5.3 6.1 11.4 16.0 19.1 64.9 12.3 4.2 13.8 11.7 13.6 8.2 9.7 8.3 17.4 12.8 13.9 14.7 2.1 26.9 8.3 15.1 35.2 12.7 37.3 16.3 9.3 8.4 10.3 8.0 53.5 14.5 17.3 9.5 8.2 10.9 14.0 11.9 7.5 32.6 11.8 6.7 67.3 15.3 14.2 9.8 5.1 12.7 5.3 10.2 7.2 82.4 8.5 11.8 6.2 72.9 74.5 13.7 14.4 9.4 13.0 12.2 14.2 40.8 21.0 11.5 26.3 8.7 7.9 21.7 11.5 14.3 5.8 11.9 9.8 13.4 17.0 12.5 PDZRN3 "KIAA1095, LNX3, SEMACAP3, SEMCAP3" ENSG00000121440 "PDZ domain containing ring finger 3" Q9UPQ7 3 73382431-73624941 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 256.0;Excitatory neurons: 183.1;Inhibitory neurons: 258.3;Microglial cells: 329.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "plasmacytoid DC: 1.9" "Lineage enriched" "Detected in single" 19 "dendritic cells: 1.9" "Cell line enhanced" "Detected in many" "AF22: 32.1;ASC diff: 57.0;ASC TERT1: 29.6;BJ hTERT+: 42.0;HSkMC: 41.4;U-87 MG: 30.4" "Group enriched" "Detected in many" 4 "amygdala: 15.1;basal ganglia: 8.1;cerebral cortex: 19.5;hippocampal formation: 16.1;white matter: 7.2" "Low region specificity" "Detected in many" "HPA038822, HPA061420" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Nucleoplasm "HPA038822: AB_10675952, HPA061420: AB_2684512" "unprognostic (3.22e-2)" "unprognostic (1.32e-1)" "unprognostic (1.00e-2)" "prognostic favorable (3.35e-5)" "unprognostic (1.09e-1)" "unprognostic (5.54e-2)" "unprognostic (8.47e-2)" "unprognostic (3.67e-1)" "unprognostic (1.60e-1)" "unprognostic (7.51e-2)" "prognostic favorable (4.93e-4)" "unprognostic (8.38e-2)" "prognostic favorable (3.65e-7)" "unprognostic (8.63e-3)" "unprognostic (1.63e-1)" "unprognostic (3.72e-2)" "unprognostic (2.86e-3)" 29.9 35.7 14.9 10.2 16.3 0.0 24.0 8.5 20.9 45.2 58.0 84.0 9.2 64.1 24.5 27.8 26.7 27.4 48.0 16.7 10.6 10.7 2.1 14.9 4.5 13.0 11.8 69.4 6.9 0.8 4.6 17.5 11.0 31.7 13.9 6.3 20.9 29.0 91.8 17.3 24.4 38.4 13.1 2.4 38.7 6.4 17.1 2.9 3.6 22.4 1.4 46.7 32.0 13.2 0.0 0.0 32.1 0.1 57.0 29.6 0.1 16.9 42.0 5.0 3.2 16.2 0.0 0.1 0.1 22.8 0.8 0.0 0.0 0.0 4.8 0.0 2.2 0.0 0.0 0.0 9.5 0.0 0.1 41.4 0.0 13.8 0.1 6.0 0.0 0.0 0.0 0.0 4.9 2.1 0.0 0.2 4.6 0.0 0.2 0.0 8.4 0.1 0.0 0.0 3.7 10.5 0.0 7.8 12.7 9.2 4.5 0.0 0.0 20.6 1.5 23.6 2.2 0.7 0.0 0.2 30.4 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 14.9 16.3 8.5 20.9 16.7 10.6 13.0 11.8 11.0 13.1 17.1 13.2 5.9 0.0 0.0 256.0 0.5 2.4 9.7 0.0 1.8 19.3 7.5 7.6 65.0 0.0 0.0 5.5 6.2 0.5 2.7 1.0 1.9 0.0 0.4 2.1 45.2 2.3 21.1 0.0 183.1 0.4 0.5 25.2 2.0 3.3 0.0 35.0 0.0 0.0 0.8 0.0 258.3 9.1 0.0 0.0 2.9 1.3 23.3 0.7 16.0 329.8 0.0 22.5 0.0 21.6 5.5 0.3 0.9 28.2 0.1 10.9 0.1 7.1 0.0 1.9 0.0 4.6 19.6 0.5 6.2 2.9 1.8 0.8 0.5 12.4 3.9 6.3 PER3 ENSG00000049246 "Period circadian regulator 3" P56645 1 7784320-7845177 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 137.8;Bipolar cells: 241.0;Horizontal cells: 124.5;Rod photoreceptor cells: 138.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-937: 36.0" "Low region specificity" "Detected in all" HPA019530 Approved Supported Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Cytosol "HPA019530: AB_1855201" "unprognostic (5.11e-2)" "prognostic favorable (7.14e-4)" "unprognostic (2.45e-2)" "unprognostic (2.97e-3)" "unprognostic (1.74e-1)" "prognostic favorable (1.34e-4)" "unprognostic (3.87e-1)" "unprognostic (5.53e-2)" "unprognostic (1.43e-1)" "unprognostic (1.77e-1)" "unprognostic (4.11e-2)" "unprognostic (8.96e-2)" "prognostic favorable (2.20e-5)" "unprognostic (1.16e-1)" "unprognostic (1.20e-1)" "unprognostic (3.46e-1)" "unprognostic (1.62e-1)" 13.9 11.1 10.1 4.6 14.1 0.7 12.6 46.1 15.9 12.4 3.1 18.4 6.4 19.0 10.6 17.0 12.6 12.2 22.3 9.6 9.9 12.5 25.6 12.0 4.7 12.7 13.9 18.5 17.0 19.8 16.9 2.7 14.4 15.6 6.6 55.9 25.4 20.5 28.7 13.4 9.4 10.7 11.8 9.0 17.4 8.8 14.4 4.6 23.3 24.3 7.2 10.3 10.4 26.0 7.2 2.1 6.1 1.8 1.1 0.6 1.8 3.0 5.5 5.5 7.6 8.6 27.7 3.2 1.6 12.4 9.4 3.3 22.1 1.4 8.3 0.2 1.2 22.7 8.3 1.3 6.8 0.7 7.6 3.0 2.4 6.0 6.1 11.4 2.0 1.6 18.7 5.8 2.4 5.7 12.7 10.2 3.3 16.0 5.9 11.0 2.2 0.2 3.1 1.3 7.9 8.5 26.3 0.1 11.0 6.1 6.6 1.0 4.2 14.9 21.4 4.6 4.0 0.8 0.5 2.7 10.5 36.0 21.2 0.3 0.6 0.4 1.5 0.7 1.8 0.6 0.7 1.4 0.7 0.2 0.6 0.7 0.0 0.3 1.3 0.5 1.3 0.6 10.1 14.1 46.1 15.9 9.6 9.9 12.7 13.9 14.4 11.8 14.4 26.0 45.0 19.2 12.1 137.8 3.9 30.1 13.1 4.3 40.5 241.0 14.3 17.3 17.0 8.6 9.9 9.2 81.3 1.7 3.0 5.0 9.8 3.2 16.5 4.4 19.6 17.5 6.6 0.0 42.8 4.8 0.5 33.6 20.4 4.3 26.0 6.9 10.8 28.1 9.4 124.5 64.1 4.0 12.2 8.5 14.8 5.8 12.5 11.2 12.4 40.3 3.4 91.2 2.1 62.4 91.6 5.7 1.6 27.4 3.3 9.7 5.0 5.2 9.7 138.5 6.6 39.2 25.4 22.2 23.2 32.9 25.6 0.5 5.9 11.5 1.7 8.6 PEX14 ENSG00000142655 "Peroxisomal biogenesis factor 14" O75381 1 10472288-10630758 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 67.3;Syncytiotrophoblasts: 64.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046104, HPA049231" Supported Supported "Nucleoli fibrillar center,Peroxisomes" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 46: Photoreceptor cells - Phototransduction" Peroxisomes "Nucleoli fibrillar center" "HPA046104: AB_2679539, HPA049231: AB_2680683" "unprognostic (7.23e-3)" "unprognostic (7.93e-2)" "unprognostic (3.50e-2)" "unprognostic (1.48e-2)" "unprognostic (3.66e-1)" "unprognostic (1.61e-1)" "unprognostic (1.43e-1)" "unprognostic (1.77e-1)" "unprognostic (5.32e-2)" "unprognostic (2.32e-1)" "unprognostic (5.85e-2)" "unprognostic (1.31e-1)" "unprognostic (3.05e-3)" "unprognostic (9.67e-3)" "unprognostic (1.37e-1)" "unprognostic (1.43e-1)" "unprognostic (3.75e-2)" 15.9 13.9 15.5 9.5 15.3 7.8 16.2 11.7 21.8 15.5 10.7 16.8 15.1 17.1 6.4 20.9 13.7 9.3 19.6 15.8 13.6 15.8 33.0 14.3 10.5 14.1 13.1 14.9 11.2 11.8 14.1 11.8 13.8 26.4 8.2 28.1 16.8 23.8 22.6 18.6 16.2 8.5 12.2 12.6 13.8 14.0 14.3 9.7 14.0 11.3 8.6 48.8 17.6 16.0 22.5 21.1 17.2 19.2 12.3 11.6 11.2 25.2 20.8 27.4 26.1 22.4 40.1 16.4 24.9 19.4 16.3 26.3 17.9 24.6 12.9 23.1 30.3 20.4 22.6 31.2 18.8 23.0 27.3 14.2 19.2 20.7 19.0 16.3 17.9 21.2 32.2 16.3 12.4 18.7 21.9 30.4 17.7 17.2 24.6 23.5 14.5 23.3 21.7 14.8 20.5 23.5 24.4 20.2 23.9 13.2 18.4 16.2 17.7 19.9 21.5 19.6 22.0 23.3 20.4 32.3 21.8 31.2 21.7 1.4 2.2 4.6 4.5 1.6 2.8 2.2 2.3 3.4 2.7 2.0 2.9 2.8 0.3 2.6 1.5 2.8 3.0 2.4 15.5 15.3 11.7 21.8 15.8 13.6 14.1 13.1 13.8 12.2 14.3 16.0 5.9 9.6 2.0 32.0 9.2 7.1 13.9 29.2 4.0 15.1 8.3 6.9 8.4 4.3 12.3 9.2 27.1 49.7 11.3 14.1 7.9 17.2 5.9 10.6 4.9 7.8 9.0 4.6 42.0 14.7 18.7 8.1 4.1 7.4 6.3 7.8 8.2 51.1 22.7 18.5 48.4 9.7 14.2 9.0 3.1 3.1 8.1 8.0 12.4 28.1 19.9 21.2 10.3 29.7 29.9 18.2 12.3 5.7 14.7 10.8 29.7 18.5 23.5 67.3 6.6 4.5 11.0 7.1 12.8 7.1 8.1 64.7 9.8 8.3 12.0 13.5 PGM1 ENSG00000079739 "Phosphoglucomutase 1" P36871 1 63593411-63660245 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" Isomerase "Congenital disorder of glycosylation, Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 1559.1;tongue: 788.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 238.4;Extravillous trophoblasts: 185.9;Hepatocytes: 214.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004666, HPA024190, HPA024637, HPA046329" Enhanced Supported Cytosol NA NA 21000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "CAB004666: AB_425590, HPA024190: AB_1855266, HPA024637: AB_1855267, HPA046329: AB_2679625" "unprognostic (2.50e-1)" "unprognostic (2.26e-3)" "unprognostic (1.74e-2)" "unprognostic (5.90e-2)" "unprognostic (1.65e-1)" "unprognostic (1.63e-1)" "unprognostic (1.28e-2)" "unprognostic (1.86e-3)" "unprognostic (2.42e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (8.74e-5)" "unprognostic (7.07e-2)" "unprognostic (1.55e-2)" "unprognostic (6.58e-3)" "unprognostic (1.37e-1)" "unprognostic (2.46e-1)" "unprognostic (9.74e-3)" 113.7 70.8 31.6 20.7 34.7 21.5 57.4 34.3 38.4 33.9 53.1 58.9 60.8 22.9 19.2 49.3 17.0 30.3 178.9 31.4 34.0 52.2 279.8 42.6 14.7 44.7 34.1 51.0 112.2 65.3 31.8 26.9 32.7 46.6 49.9 22.6 41.8 49.7 1559.1 30.6 55.1 41.4 31.9 14.7 30.6 11.1 36.5 14.3 27.5 788.0 19.4 38.4 22.1 30.2 113.4 47.0 17.3 57.0 111.0 81.4 138.6 45.7 61.8 48.9 79.0 38.8 51.3 35.8 93.2 71.2 107.4 26.5 24.0 96.3 55.9 44.0 32.1 75.3 72.6 40.3 91.6 66.8 4.3 103.4 60.7 57.1 88.5 129.8 29.6 36.3 0.1 46.3 78.8 6.9 19.6 36.7 78.3 3.4 73.9 26.8 80.0 11.8 70.0 35.3 10.4 66.7 100.0 103.0 157.4 78.6 32.4 25.2 3.1 71.6 36.0 64.0 39.4 29.1 45.5 57.8 117.0 58.0 31.5 46.0 33.2 49.2 40.5 22.4 32.7 22.4 23.5 31.0 48.4 11.8 21.0 24.7 38.7 43.9 21.2 13.9 20.4 35.4 31.6 34.7 34.3 38.4 31.4 34.0 44.7 34.1 32.7 31.9 36.5 30.2 8.4 93.0 29.4 48.3 16.9 17.8 29.0 58.8 47.8 9.2 33.8 21.8 139.2 48.6 24.2 16.5 10.4 76.6 14.2 81.8 88.0 55.9 32.0 8.2 12.1 12.7 13.1 5.7 17.9 238.4 185.9 37.0 27.0 13.5 5.1 134.3 15.0 214.4 24.6 0.0 26.3 47.5 20.3 17.0 10.8 8.5 22.1 13.5 26.6 4.7 32.8 75.8 29.9 32.2 9.8 70.5 31.6 38.0 40.4 29.2 90.2 74.8 17.0 11.4 13.1 53.4 25.5 5.6 10.1 57.3 18.2 58.8 19.0 20.2 81.5 19.0 PI4K2B "FLJ11105, PI4KIIB, PIK42B" ENSG00000038210 "Phosphatidylinositol 4-kinase type 2 beta" Q8TCG2 4 25160663-25279204 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 57.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004099 Enhanced Supported Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "HPA004099: AB_1855353" "unprognostic (1.02e-1)" "unprognostic (6.34e-3)" "prognostic favorable (9.64e-5)" "unprognostic (2.75e-2)" "unprognostic (1.98e-2)" "unprognostic (2.68e-2)" "unprognostic (7.54e-2)" "unprognostic (7.75e-2)" "unprognostic (5.06e-1)" "unprognostic (6.39e-3)" "unprognostic (1.71e-1)" "unprognostic (1.32e-1)" "unprognostic (9.07e-2)" "unprognostic (9.61e-2)" "unprognostic (2.39e-2)" "unprognostic (2.02e-2)" "unprognostic (4.47e-2)" 7.9 8.9 3.4 14.0 3.9 14.1 16.5 3.6 4.5 11.4 5.8 18.7 39.0 8.0 5.8 16.7 8.7 8.3 4.5 3.2 4.1 12.9 57.9 16.5 18.1 4.3 3.6 5.2 9.5 7.7 3.4 12.0 4.5 11.4 20.4 4.9 23.5 7.9 2.4 13.1 31.6 9.1 4.5 13.5 22.7 12.1 3.7 19.7 24.1 4.8 18.9 14.3 8.1 5.3 33.8 9.9 16.7 14.6 18.2 33.9 31.3 50.8 48.6 48.4 58.1 14.0 37.7 86.3 11.5 45.3 37.5 14.7 37.3 24.6 41.7 28.9 12.2 30.4 23.3 26.1 14.2 61.9 21.0 21.6 17.9 18.6 19.2 12.9 28.0 27.0 20.7 76.2 37.0 18.8 58.3 39.7 23.6 40.5 13.6 34.4 58.1 47.5 32.2 32.2 28.9 6.2 24.5 17.1 12.0 17.0 25.7 27.3 33.8 31.8 8.4 18.3 32.5 76.3 49.5 77.4 34.5 45.4 30.6 5.3 1.1 3.4 1.5 1.2 1.0 1.4 1.5 1.5 0.8 1.2 1.2 1.4 1.7 0.9 0.9 1.5 3.5 0.6 3.4 3.9 3.6 4.5 3.2 4.1 4.3 3.6 4.5 4.5 3.7 5.3 5.6 6.4 18.5 21.5 14.9 15.0 15.8 9.9 8.0 2.1 8.4 5.3 0.0 5.7 12.2 9.2 0.0 21.6 6.7 20.2 5.9 5.5 1.0 10.0 3.4 7.1 8.4 25.7 8.7 7.1 12.6 6.1 16.3 8.5 0.0 3.5 6.8 40.4 10.3 1.7 13.7 13.7 8.2 15.4 13.9 1.0 4.4 8.6 5.4 11.2 10.3 0.7 4.1 30.2 20.1 5.8 8.2 4.5 27.4 14.1 16.8 20.3 10.4 3.4 0.0 5.3 7.2 9.6 10.3 18.3 15.6 13.5 10.3 4.4 13.9 18.2 PID1 "FLJ20701, NYGGF4" ENSG00000153823 "Phosphotyrosine interaction domain containing 1" Q7Z2X4 2 228850526-229271287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 135.0;Inhibitory neurons: 142.2;Langerhans cells: 210.4;Microglial cells: 179.9;Oligodendrocyte precursor cells: 543.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 71.1;intermediate monocyte: 79.4;myeloid DC: 83.6" "Group enriched" "Detected in many" 53 "dendritic cells: 83.6;monocytes: 79.4" "Cell line enhanced" "Detected in many" "ASC diff: 54.5;hTEC/SVTERT24-B: 86.1;LHCN-M2: 57.3;REH: 62.3;RH-30: 90.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036103 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA036103: AB_10602144" "unprognostic (8.46e-2)" "unprognostic (2.96e-1)" "unprognostic (3.55e-2)" "unprognostic (5.52e-2)" "unprognostic (9.40e-3)" "unprognostic (2.66e-2)" "unprognostic (1.21e-2)" "unprognostic (6.36e-2)" "unprognostic (1.54e-2)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.46e-1)" "unprognostic (4.91e-3)" "unprognostic (9.98e-3)" "unprognostic (1.11e-1)" "unprognostic (5.34e-2)" "unprognostic (9.61e-6)" 31.2 29.5 18.8 13.9 20.8 2.9 25.8 9.0 21.2 30.2 9.0 37.6 5.5 22.9 8.9 12.0 33.9 12.7 17.0 20.6 15.5 5.6 62.2 24.4 4.4 14.8 30.5 31.0 13.8 1.5 8.8 26.1 13.6 19.2 21.5 3.8 10.2 14.8 13.1 20.0 25.1 16.7 11.8 20.3 25.5 5.5 21.4 3.4 16.6 20.8 3.6 30.9 27.0 13.8 0.0 1.9 0.0 0.0 54.5 10.5 0.1 9.2 34.7 5.8 7.1 0.7 0.0 0.0 0.2 13.0 18.0 1.7 0.0 1.7 7.8 0.0 0.0 0.0 4.0 0.1 22.3 0.0 0.1 19.8 15.5 86.1 14.0 16.1 0.0 0.0 0.0 0.1 57.3 0.1 0.1 0.0 0.9 7.6 5.2 62.3 90.7 0.1 1.1 0.0 1.8 2.3 19.4 1.8 0.1 0.7 0.2 0.0 0.0 22.3 8.3 21.1 8.8 0.1 0.0 0.0 29.3 0.1 3.7 0.0 71.1 0.0 0.0 79.4 0.4 0.2 0.0 0.2 83.6 0.0 0.0 0.0 1.5 0.0 16.7 0.4 0.3 28.4 18.8 20.8 9.0 21.2 20.6 15.5 14.8 30.5 13.6 11.8 21.4 13.8 4.0 6.4 70.9 53.8 1.6 15.6 6.1 13.5 6.8 5.7 0.9 1.7 2.6 8.6 11.1 0.0 0.0 1.9 0.2 75.7 0.0 2.5 0.1 1.4 37.8 4.1 4.9 0.4 121.0 4.0 31.5 107.3 1.1 4.4 6.3 7.8 4.2 135.0 3.3 0.0 142.2 11.9 4.1 42.5 210.4 1.9 88.0 50.1 21.4 179.9 35.2 14.0 1.0 543.4 3.5 1.6 24.2 75.2 0.5 21.9 39.5 0.3 2.5 1.3 0.0 4.8 8.7 0.4 2.1 1.4 14.5 4.8 2.4 41.0 36.0 1.4 PIK3R1 "GRB1, p85, p85-ALPHA" ENSG00000145675 "Phosphoinositide-3-kinase regulatory subunit 1" P27986 5 68215756-68301821 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction, Protein transport, Stress response, Transport" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "dendritic cells: 410.2;Endometrial stromal cells: 479.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 265.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001216, CAB004268" Approved Approved Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Cytosol "CAB004268: AB_628126, HPA001216: AB_1079612" "unprognostic (5.74e-2)" "unprognostic (6.58e-2)" "unprognostic (2.01e-1)" "unprognostic (1.31e-2)" "unprognostic (1.18e-1)" "unprognostic (1.33e-2)" "prognostic favorable (8.09e-4)" "unprognostic (3.78e-3)" "unprognostic (1.78e-1)" "unprognostic (2.71e-1)" "unprognostic (6.10e-2)" "unprognostic (1.32e-1)" "unprognostic (4.59e-3)" "unprognostic (5.66e-3)" "unprognostic (1.27e-1)" "unprognostic (5.92e-2)" "unprognostic (1.54e-1)" 60.6 27.3 13.6 27.8 33.3 126.4 92.1 12.5 40.8 51.2 0.6 38.2 17.2 65.8 45.0 43.2 69.0 35.0 72.3 29.9 13.0 35.9 100.8 26.7 28.5 11.2 22.1 53.3 13.4 40.2 7.3 32.4 12.0 26.7 22.2 59.9 64.5 31.9 63.5 28.7 24.5 74.8 9.9 38.1 18.3 8.6 20.3 46.5 20.6 33.9 23.7 27.0 31.7 36.0 4.3 8.2 23.8 71.4 265.5 76.9 10.4 23.2 10.6 8.8 9.4 20.4 7.4 21.8 38.5 32.0 4.3 10.2 6.7 46.9 11.0 90.6 8.9 26.1 6.5 17.0 89.2 27.0 20.1 81.9 104.2 16.1 83.6 4.1 11.7 25.0 4.1 16.1 8.1 11.3 65.7 10.5 6.9 14.7 4.3 61.1 11.3 17.0 11.5 47.9 4.7 21.3 4.0 6.3 15.0 13.7 34.3 19.0 14.0 10.3 10.4 17.3 14.8 18.0 29.2 25.2 11.1 32.9 7.8 22.0 1.7 8.8 11.5 2.4 16.6 1.7 14.9 11.1 3.0 3.9 18.6 14.1 2.2 11.7 6.5 1.2 12.3 5.5 13.6 33.3 12.5 40.8 29.9 13.0 11.2 22.1 12.0 9.9 20.3 36.0 47.7 51.3 24.8 112.3 47.7 14.4 23.5 30.8 175.2 46.0 61.4 168.4 263.0 38.6 19.3 5.5 25.0 13.4 410.2 28.4 72.4 15.8 12.6 38.7 479.9 39.0 9.6 43.5 232.8 9.5 18.5 151.0 43.8 93.2 68.9 110.4 31.1 198.3 30.7 48.8 82.7 32.6 28.5 69.2 24.7 11.9 172.1 68.8 33.8 117.1 37.6 194.1 137.0 281.5 199.9 12.3 19.8 122.2 173.2 8.4 24.3 39.1 8.7 89.4 19.7 127.2 76.5 1.7 4.5 37.2 10.2 10.0 309.9 45.4 36.5 8.1 PLA2R1 "CLEC13C, PLA2-R, PLA2G1R, PLA2IR" ENSG00000153246 "Phospholipase A2 receptor 1" Q13018 2 159932006-160062615 "Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 39.1;thyroid gland: 41.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 33.1;Excitatory neurons: 34.6;Inhibitory neurons: 43.5;Muller glia cells: 33.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 14.5;ASC TERT1: 19.5;BJ hTERT+: 16.2;hTERT-RPE1: 26.3;TIME: 47.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB068217, CAB068218" Approved Approved Cytosol "Secreted to blood" NA NA 960000 "Cluster 1: Thyroid gland - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "CAB068217: AB_2665660, CAB068218: AB_2665661" "unprognostic (2.04e-1)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.39e-2)" "unprognostic (4.91e-3)" "unprognostic (6.01e-2)" "unprognostic (9.71e-2)" "unprognostic (1.09e-1)" "unprognostic (1.40e-2)" "unprognostic (9.38e-3)" "unprognostic (4.30e-3)" "unprognostic (2.82e-1)" "unprognostic (2.14e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (2.62e-1)" "unprognostic (6.58e-2)" "unprognostic (2.02e-1)" 4.7 2.9 0.7 1.4 0.8 0.0 14.9 9.7 2.2 6.9 1.7 3.1 3.9 8.8 2.9 4.7 5.4 9.3 2.5 0.5 1.5 20.8 1.4 2.6 1.9 2.0 2.7 10.8 0.6 19.7 2.2 3.8 2.1 3.1 3.2 5.6 39.1 2.9 0.5 10.9 6.1 6.9 1.4 5.1 1.6 1.0 2.5 0.6 41.9 1.3 2.7 3.9 6.0 1.0 0.2 1.6 0.6 0.0 14.5 19.5 0.1 6.8 16.2 1.3 1.8 0.0 3.4 0.0 0.4 7.2 1.4 3.3 0.1 5.0 1.4 0.0 0.0 0.0 11.8 0.0 1.2 0.0 0.0 7.9 5.4 1.9 2.1 26.3 9.3 0.0 0.0 0.0 2.3 0.1 0.0 0.0 0.2 0.1 2.6 0.0 0.0 0.0 1.4 0.7 0.0 0.0 11.8 2.2 0.0 1.7 2.6 0.2 47.3 0.0 0.8 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.7 0.8 9.7 2.2 0.5 1.5 2.0 2.7 2.1 1.4 2.5 1.0 11.1 6.4 2.8 20.9 0.1 9.4 2.7 18.1 21.6 2.7 22.1 14.5 4.1 5.7 11.3 33.1 0.0 7.3 0.5 1.7 0.0 0.6 0.1 5.6 22.0 4.0 1.2 0.0 34.6 2.0 1.3 14.8 0.0 9.4 1.3 9.6 8.6 0.0 0.6 16.8 43.5 7.2 4.1 0.0 2.1 1.4 16.1 0.5 7.2 25.3 0.0 33.5 0.0 5.5 1.8 5.1 11.3 16.6 0.1 2.6 15.6 2.3 8.1 1.4 6.6 3.4 4.8 0.1 1.0 9.3 5.4 1.5 0.6 6.3 7.5 3.0 PLAAT2 "FLJ20556, HRASLS2, PLAAT-2" ENSG00000133328 "Phospholipase A and acyltransferase 2" Q9NWW9 11 63552770-63563379 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 67.9" "Cell type enhanced" "Detected in single" "dendritic cells: 2.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 8 "memory B-cell: 17.3;naive B-cell: 8.2" "Lineage enriched" "Detected in many" 10 "B-cells: 17.3" "Cell line enriched" "Detected in some" 8 "U-266/70: 128.9" HPA058997 Approved Approved Mitochondria NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "HPA058997: AB_2683874" "unprognostic (4.76e-2)" "prognostic favorable (6.87e-4)" "unprognostic (1.20e-1)" "unprognostic (3.07e-2)" "unprognostic (1.43e-1)" "unprognostic (1.43e-1)" "unprognostic (1.82e-1)" "unprognostic (1.53e-1)" "unprognostic (9.69e-2)" "unprognostic (3.91e-3)" "prognostic unfavorable (5.27e-5)" "unprognostic (1.56e-1)" "unprognostic (2.29e-1)" "unprognostic (1.38e-2)" "unprognostic (2.51e-1)" "unprognostic (2.43e-1)" "unprognostic (1.57e-2)" 0.3 0.0 0.6 0.8 0.6 0.1 9.1 0.5 0.9 0.9 0.3 11.2 67.9 0.3 1.2 1.5 4.7 0.6 0.2 0.5 0.5 8.6 4.6 3.6 0.3 0.7 0.6 0.2 0.0 0.0 0.2 0.2 0.6 0.4 13.7 0.0 0.9 0.5 0.0 0.3 42.5 0.3 0.5 0.7 12.4 0.5 0.6 0.3 0.9 0.0 0.3 1.3 0.2 1.1 0.4 1.7 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.4 0.1 0.3 15.6 0.0 0.9 0.0 0.4 1.0 0.6 0.2 0.1 0.2 0.0 0.1 1.0 0.1 0.2 0.0 0.1 0.1 1.2 0.3 0.0 0.7 0.0 0.0 0.0 6.7 0.0 0.0 0.2 0.3 0.1 8.7 1.9 0.0 0.0 1.5 0.6 0.0 0.0 0.2 0.1 4.0 0.0 0.1 2.2 0.1 0.0 0.0 0.0 0.1 0.0 128.9 16.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.9 17.3 0.2 1.0 0.1 8.2 0.2 0.7 0.1 1.6 0.0 0.9 0.0 3.9 0.6 0.6 0.5 0.9 0.5 0.5 0.7 0.6 0.6 0.5 0.6 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 PLD1 ENSG00000075651 "Phospholipase D1" Q13393 3 171600404-171810950 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 86.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 519.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 57.5;SK-MEL-30: 31.1;TIME: 50.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004527, HPA042396, HPA066938" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles Nucleoplasm "CAB004527: AB_677324, HPA042396: AB_2677977, HPA066938: " "unprognostic (3.23e-1)" "unprognostic (3.27e-1)" "unprognostic (5.82e-2)" "unprognostic (5.13e-2)" "unprognostic (4.58e-1)" "unprognostic (4.76e-2)" "unprognostic (9.03e-2)" "unprognostic (1.46e-1)" "unprognostic (6.23e-2)" "unprognostic (8.02e-2)" "unprognostic (2.06e-2)" "unprognostic (2.95e-2)" "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (4.76e-6)" 7.8 26.4 9.2 6.6 24.7 7.8 7.5 18.4 13.6 10.4 4.5 14.6 46.9 6.2 2.8 33.0 6.4 86.8 24.4 10.5 14.3 12.0 33.7 4.7 9.1 24.8 22.0 24.2 21.2 1.6 2.3 10.7 23.5 3.4 14.7 0.5 13.8 6.0 2.5 29.2 43.9 4.8 14.7 15.7 8.2 5.0 19.0 4.1 3.7 6.8 10.8 5.1 12.4 41.4 4.5 7.2 3.7 1.4 11.2 12.6 7.7 2.3 9.9 3.5 4.3 1.1 6.4 0.0 17.0 0.9 24.0 15.2 0.6 2.0 5.7 3.6 3.2 4.2 11.5 26.1 4.9 7.3 18.9 4.9 10.9 4.2 2.0 10.0 57.5 1.2 2.8 0.0 0.9 1.3 0.0 6.4 0.8 11.9 5.1 0.2 1.5 0.1 8.9 1.8 0.1 0.1 7.9 4.7 31.1 5.1 9.0 9.7 50.7 1.5 5.7 4.0 2.5 9.6 8.2 0.1 6.7 8.6 1.9 8.3 1.8 2.3 0.3 1.1 2.6 0.0 0.2 0.6 0.6 0.0 0.0 0.1 1.0 2.2 0.4 0.0 0.8 0.6 9.2 24.7 18.4 13.6 10.5 14.3 24.8 22.0 23.5 14.7 19.0 41.4 7.7 0.0 4.7 2.0 0.9 7.1 3.4 11.0 10.8 0.4 4.9 5.6 33.6 57.2 11.1 1.8 0.0 3.0 1.9 37.5 3.9 8.4 13.1 1.0 4.8 7.4 4.2 6.3 8.9 3.4 3.7 15.7 27.0 1.3 27.9 10.4 6.4 15.9 20.0 0.0 12.1 23.6 6.1 13.2 2.4 9.5 10.5 10.2 12.4 98.4 5.4 0.0 1.0 12.5 519.6 2.4 18.3 4.5 3.4 0.7 38.3 48.0 9.9 0.1 19.7 3.8 8.4 6.1 5.3 93.5 34.9 2.3 2.3 12.1 17.8 4.7 PLEKHG5 "GEF720, KIAA0720, Syx, Tech" ENSG00000171680 "Pleckstrin homology and RhoGEF domain containing G5" O94827 1 6467122-6520074 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 57.4;skin 1: 102.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 17.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 57.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 32.1;TIME: 30.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049570 Uncertain Approved Nucleoplasm NA NA "Cluster 61: Skin - Cornification" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA049570: AB_2680818" "unprognostic (5.59e-2)" "unprognostic (1.33e-1)" "unprognostic (2.47e-1)" "unprognostic (2.81e-1)" "unprognostic (1.50e-3)" "unprognostic (5.10e-2)" "unprognostic (1.02e-1)" "unprognostic (5.46e-2)" "unprognostic (4.40e-2)" "unprognostic (1.02e-2)" "unprognostic (4.85e-1)" "unprognostic (2.70e-2)" "unprognostic (1.28e-3)" "unprognostic (4.85e-1)" "unprognostic (1.20e-1)" "unprognostic (3.13e-1)" "unprognostic (4.85e-2)" 18.7 15.0 4.4 2.9 2.6 0.6 12.0 57.4 16.6 14.0 0.0 7.3 6.4 7.5 1.9 21.6 8.6 7.3 16.4 13.0 0.0 6.5 1.8 6.0 5.0 0.0 0.0 7.5 5.1 4.4 43.3 12.4 1.8 9.9 3.5 3.4 9.3 7.2 6.8 102.5 8.4 3.9 0.0 50.9 4.4 5.4 0.0 2.0 7.2 3.0 3.3 5.9 14.3 0.0 7.1 2.7 11.9 9.4 1.5 4.2 3.1 8.4 7.0 3.2 2.1 6.9 18.8 0.3 22.6 2.8 4.9 22.6 2.2 23.7 1.3 16.5 3.0 0.0 15.1 2.9 1.9 0.0 1.3 5.5 10.2 8.1 12.5 17.4 24.9 1.7 0.0 1.5 0.6 5.0 0.5 32.1 4.9 2.3 23.8 0.1 2.7 2.3 6.3 3.1 10.5 25.2 1.1 8.2 1.5 5.3 8.2 0.5 30.3 8.1 5.0 0.0 6.6 0.1 0.0 2.4 9.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 2.6 57.4 16.6 13.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 10.6 0.0 1.5 1.0 0.2 7.4 2.3 4.7 8.0 1.4 1.4 2.2 4.1 1.5 3.6 3.7 2.1 2.6 0.1 4.2 0.0 1.3 8.6 2.5 5.9 9.8 3.5 0.4 17.4 1.3 4.0 1.9 3.1 3.2 0.0 4.0 7.5 0.3 5.3 1.7 9.6 6.4 6.1 0.8 1.3 5.7 1.8 2.4 0.0 7.5 0.0 9.7 0.0 2.0 1.2 5.1 5.6 8.6 0.4 3.8 4.1 0.4 2.7 1.5 13.1 2.1 1.7 2.1 5.1 10.8 14.5 1.9 0.7 2.5 2.8 5.8 PLG ENSG00000122194 Plasminogen P00747 6 160702238-160754097 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Tissue remodeling" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 2666.4" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 1772.7" "Cancer enriched" "Detected in some" 84 "liver cancer: 180.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000668, CAB016678, HPA021602, HPA048823" Supported "Secreted to blood" NA NA 140000000000 45000000000 "Cluster 85: Liver - Metabolism" "Cluster 15: Hepatocytes - Hemostasis" "CAB000668: , CAB016678: AB_1621208, HPA021602: AB_1855453, HPA048823: AB_2680532" "unprognostic (1.70e-1)" "unprognostic (2.16e-3)" "unprognostic (2.44e-1)" "unprognostic (8.54e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-3)" "unprognostic (6.28e-2)" "unprognostic (7.25e-2)" "prognostic favorable (4.22e-4)" "unprognostic (3.97e-3)" "unprognostic (5.21e-2)" "unprognostic (2.33e-2)" 0.4 0.4 0.3 0.2 0.4 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.3 0.2 0.0 0.1 2.4 0.5 0.1 0.2 0.3 240.9 2666.4 0.4 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.1 0.9 0.0 0.1 0.2 0.1 0.0 0.0 0.5 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.5 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.3 0.2 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.3 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 5.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.6 30.0 0.0 1.8 0.0 0.0 0.3 0.0 19.6 0.0 0.2 3.0 0.1 1.2 0.0 24.0 0.6 0.0 0.0 0.0 0.0 0.1 1.3 0.0 28.5 1772.7 0.1 0.0 0.5 0.0 0.0 35.4 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 235.7 1.5 0.1 0.0 0.4 0.2 0.4 0.4 0.0 0.0 0.0 2.3 0.1 0.0 0.0 PLLP "PMLP, TM4SF11" ENSG00000102934 Plasmolipin Q9Y342 16 57248547-57284672 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 10 "brain: 844.1;choroid plexus: 1086.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 161.5;Glandular and luminal cells: 134.3;Oligodendrocyte precursor cells: 140.2;Oligodendrocytes: 193.4;Pancreatic endocrine cells: 119.0;Proximal enterocytes: 149.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "naive CD4 T-cell: 14.5;naive CD8 T-cell: 5.7" "Lineage enriched" "Detected in many" 8 "T-cells: 14.5" "Cell line enhanced" "Detected in many" "EFO-21: 27.8;Hep G2: 81.1;OE19: 79.6;RPTEC TERT1: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041862 Enhanced NA NA "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 44: Endometrium - Transcription" "HPA041862: AB_2677712" "unprognostic (7.96e-2)" "unprognostic (2.07e-3)" "unprognostic (3.86e-2)" "prognostic favorable (2.80e-4)" "unprognostic (3.19e-1)" "unprognostic (1.42e-1)" "unprognostic (9.56e-2)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" "unprognostic (5.64e-2)" "unprognostic (6.99e-3)" "unprognostic (2.83e-2)" "prognostic favorable (6.21e-9)" "unprognostic (2.06e-2)" "unprognostic (9.06e-3)" "unprognostic (3.86e-1)" "unprognostic (3.32e-2)" 14.5 2.8 549.6 2.3 673.5 2.3 12.1 352.7 646.8 24.6 1086.0 10.5 33.5 6.3 2.4 34.3 22.6 27.4 8.4 489.4 603.1 41.0 9.8 50.7 2.4 769.3 601.6 3.0 52.5 14.8 4.4 2.6 775.8 12.8 12.6 2.0 41.9 27.9 3.8 99.5 33.4 2.4 689.1 19.6 79.8 6.2 844.1 1.1 12.8 6.3 4.9 9.6 26.1 779.6 1.6 5.7 7.1 1.4 0.0 0.1 3.6 1.1 0.3 0.4 0.3 15.9 6.8 0.5 27.8 0.0 1.8 5.2 3.3 5.0 0.1 1.6 2.7 7.3 3.0 81.1 1.0 0.7 1.8 0.2 1.2 0.1 0.6 3.6 8.0 1.7 1.3 1.9 0.1 2.0 0.9 1.8 5.9 79.6 2.3 0.9 1.3 1.4 33.5 17.1 1.6 2.8 1.9 2.2 3.3 2.2 11.7 2.2 6.0 1.2 1.6 1.0 1.3 1.4 1.7 0.9 1.6 0.5 4.7 1.7 1.0 0.7 0.8 0.5 0.6 0.7 2.2 0.6 0.2 1.2 14.5 5.7 1.8 0.6 0.5 0.5 0.6 2.2 549.6 673.5 352.7 646.8 489.4 603.1 769.3 601.6 775.8 689.1 844.1 779.6 18.4 64.1 26.5 0.3 1.4 13.9 15.9 61.4 22.8 2.7 23.8 23.6 3.2 161.5 26.4 90.1 2.1 2.2 1.8 26.6 15.6 61.3 0.9 66.9 12.4 20.5 1.2 5.3 0.5 70.2 1.3 5.1 76.0 134.3 3.8 13.4 11.0 4.2 0.7 5.0 0.7 23.7 93.6 0.8 2.2 1.5 4.7 2.1 3.6 25.3 1.3 0.5 0.0 140.2 193.4 119.0 66.8 22.2 1.3 5.8 149.9 28.6 4.0 7.7 0.0 3.6 4.0 1.6 3.3 54.2 42.8 1.1 2.4 1.2 36.1 13.3 PON3 ENSG00000105852 "Paraoxonase 3" Q15166 7 95359872-95396375 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 616.7" "Cell type enriched" "Detected in many" 11 "Hepatocytes: 509.6" "Group enriched" "Detected in many" 9 "liver cancer: 30.8;lung cancer: 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 28.9;CACO-2: 8.6;CAPAN-2: 6.5;Hep G2: 32.6;T-47d: 17.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA014848, CAB025250" Enhanced "Secreted to blood" NA NA 1760000000 380000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB025250: , HPA014848: AB_1855540" "unprognostic (2.67e-1)" "unprognostic (1.03e-1)" "unprognostic (6.28e-3)" "unprognostic (5.52e-3)" "unprognostic (1.36e-1)" "unprognostic (4.87e-1)" "unprognostic (1.44e-3)" "unprognostic (6.32e-2)" "unprognostic (1.11e-1)" "unprognostic (6.44e-3)" "unprognostic (9.14e-2)" "unprognostic (7.18e-3)" "unprognostic (8.30e-9)" "unprognostic (1.66e-1)" "unprognostic (1.04e-2)" "unprognostic (8.29e-2)" "unprognostic (5.12e-2)" 1.4 3.8 2.1 0.5 2.0 0.0 31.2 1.7 1.9 5.3 1.4 2.0 7.9 0.9 3.6 0.5 1.3 4.4 1.0 1.8 2.1 2.7 616.7 14.2 0.1 2.3 2.2 12.4 14.3 0.2 24.9 0.8 2.9 0.9 2.8 0.1 26.3 3.9 0.3 7.4 3.1 0.2 2.1 0.3 2.3 9.0 2.1 1.6 7.1 0.3 5.9 1.4 0.9 1.9 3.1 28.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 6.5 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 5.3 0.0 0.1 17.4 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.0 1.7 1.9 1.8 2.1 2.3 2.2 2.9 2.1 2.1 1.9 2.5 6.4 45.9 24.5 0.6 0.9 0.9 9.3 1.8 0.0 5.4 4.3 0.5 31.5 23.9 3.7 0.0 1.7 0.3 3.2 1.9 0.3 14.5 0.0 0.4 1.9 0.0 8.0 0.1 2.0 2.2 5.2 0.5 0.0 0.0 0.4 10.0 509.6 0.2 0.0 0.2 1.8 12.2 8.1 0.3 4.8 8.1 0.2 14.2 4.7 0.0 3.2 0.0 17.6 0.1 1.2 1.2 3.0 0.0 2.1 6.0 6.7 6.5 0.1 0.0 0.8 2.1 21.4 16.9 0.3 1.3 1.4 0.8 6.6 2.3 0.4 POU2AF1 "BOB1, OBF1" ENSG00000110777 "POU class 2 homeobox associating factor 1" Q16633 11 111352255-111455630 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.6;lymphoid tissue: 119.4;stomach 1: 40.1" "Cell type enriched" "Detected in many" 4 "Plasma cells: 566.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "memory B-cell: 33.5;naive B-cell: 24.0" "Lineage enriched" "Detected in many" 9 "B-cells: 33.5" "Group enriched" "Detected in many" 4 "Daudi: 307.2;Karpas-707: 339.3;U-266/70: 326.6;U-266/84: 159.9;U-698: 610.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB011193 Enhanced NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB011193: AB_532299" "prognostic favorable (1.68e-4)" "prognostic favorable (1.63e-4)" "unprognostic (1.04e-2)" "unprognostic (5.50e-3)" "unprognostic (1.88e-1)" "prognostic favorable (3.59e-4)" "unprognostic (2.09e-1)" "unprognostic (3.63e-3)" "unprognostic (7.15e-2)" "unprognostic (2.52e-2)" "unprognostic (1.34e-1)" "unprognostic (4.81e-2)" "unprognostic (8.51e-8)" "unprognostic (2.35e-1)" "unprognostic (3.90e-1)" "unprognostic (7.14e-3)" "unprognostic (1.23e-1)" 1.9 1.2 6.4 49.0 4.9 8.1 5.6 4.2 7.0 1.7 20.3 15.7 22.2 1.5 1.3 2.9 1.3 4.7 1.4 5.4 3.6 1.4 1.4 3.3 99.3 6.2 6.1 1.1 0.6 0.3 0.1 2.8 7.2 1.8 13.4 6.5 12.9 1.9 1.8 1.1 38.6 1.2 2.7 79.5 40.1 1.6 5.4 9.6 2.8 0.3 119.4 9.3 1.9 7.3 0.9 0.9 0.3 0.4 5.6 5.2 1.0 0.2 0.1 0.1 0.1 1.1 0.3 307.2 0.7 0.3 0.2 0.8 0.9 0.4 0.1 0.9 0.2 0.5 1.0 1.1 0.1 0.6 1.7 0.2 0.3 0.3 0.6 0.5 0.3 3.4 11.8 339.3 0.3 0.8 1.5 1.6 0.4 0.5 0.5 65.3 0.7 83.0 0.2 0.8 0.6 6.1 0.7 0.3 0.2 2.4 1.3 0.9 2.7 0.5 3.1 0.6 0.5 326.6 159.9 610.8 0.4 0.7 0.5 3.8 0.2 0.6 0.3 0.2 0.2 33.5 0.5 0.2 0.1 24.0 0.4 0.2 1.6 0.5 0.4 0.3 1.2 1.2 6.4 4.9 4.2 7.0 5.4 3.6 6.2 6.1 7.2 2.7 5.4 7.3 0.0 0.0 3.6 0.3 131.3 0.3 7.1 12.3 0.0 0.0 0.0 0.9 1.9 10.0 20.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 8.4 24.9 0.6 0.2 3.0 6.6 0.1 5.7 0.0 0.8 4.6 0.5 0.0 0.1 0.7 2.4 0.1 0.0 0.1 0.7 2.0 0.6 0.4 10.9 0.3 0.8 8.8 1.0 0.3 0.0 1.0 0.0 4.6 0.4 1.2 0.4 566.8 1.2 0.0 0.4 65.0 0.0 0.0 0.1 1.0 6.3 1.8 0.8 0.0 0.0 4.2 0.0 0.8 8.4 PRICKLE1 "EPM1B, FLJ31937, RILP" ENSG00000139174 "Prickle planar cell polarity protein 1" Q96MT3 12 42456757-42590355 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 72.8;Excitatory neurons: 307.7;Inhibitory neurons: 122.2;Microglial cells: 64.6;Oligodendrocyte precursor cells: 114.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 6.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 7.6;naive B-cell: 11.5" "Lineage enriched" "Detected in many" 4 "B-cells: 11.5" "Cell line enriched" "Detected in many" 18 "HBEC3-KT: 1015.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001379, HPA050037" Approved Approved Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA001379: AB_1855703, HPA050037: " "unprognostic (2.44e-1)" "unprognostic (2.50e-1)" "unprognostic (1.81e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (3.93e-4)" "unprognostic (1.22e-1)" "unprognostic (2.34e-4)" "unprognostic (3.53e-1)" "unprognostic (1.69e-2)" "unprognostic (5.89e-2)" "unprognostic (5.29e-2)" "unprognostic (7.77e-2)" "unprognostic (1.21e-3)" "unprognostic (2.29e-4)" "unprognostic (1.12e-1)" "unprognostic (8.95e-3)" "unprognostic (5.33e-4)" 6.3 3.0 3.7 5.2 5.0 1.7 5.0 0.0 7.2 12.5 0.0 4.2 2.6 12.1 1.6 2.4 6.4 10.0 13.8 4.2 0.0 5.0 1.7 9.5 4.6 0.1 1.3 12.5 2.0 1.4 2.0 5.3 0.0 5.1 2.2 4.2 7.8 5.6 3.9 4.7 2.4 12.7 0.0 14.8 2.9 6.0 3.9 1.6 7.9 4.6 3.4 5.5 6.3 1.0 7.7 4.4 17.0 0.5 12.4 13.1 0.5 11.0 5.2 3.0 5.1 0.5 16.0 0.5 31.4 1.6 0.0 2.9 12.5 1015.4 3.5 0.6 6.4 17.5 0.9 0.4 1.7 0.3 0.2 19.3 7.5 12.7 1.7 1.8 39.7 0.3 1.8 3.1 2.9 0.3 0.1 0.5 56.1 0.1 18.0 0.2 0.7 0.1 21.1 0.7 4.4 3.0 0.3 0.7 0.7 13.7 0.3 35.1 2.9 0.9 13.4 14.0 14.2 0.9 0.6 6.1 0.2 10.7 0.6 2.6 1.8 0.4 0.2 1.0 0.7 7.6 0.2 0.2 1.0 11.5 0.4 0.2 2.4 0.5 0.6 1.6 0.2 0.9 3.7 5.0 0.0 7.2 4.2 0.0 0.1 1.3 0.0 0.0 3.9 1.0 6.9 16.0 8.2 8.8 13.2 2.7 5.3 7.3 4.0 13.5 4.0 2.2 5.7 14.3 2.6 1.8 2.1 0.6 0.2 0.0 0.0 3.8 72.8 5.2 43.0 8.1 0.0 0.4 307.7 2.6 0.2 19.2 3.6 8.6 1.3 59.1 14.6 0.1 0.6 8.4 122.2 0.0 2.0 0.9 2.3 25.4 9.9 1.2 7.2 64.6 1.1 2.7 0.0 114.6 5.3 3.9 0.1 24.8 3.1 1.0 0.0 3.3 0.3 4.5 0.0 3.8 7.9 5.1 4.8 1.9 1.4 0.7 1.1 18.6 0.0 0.8 PRKAR2B PRKAR2 ENSG00000005249 "Protein kinase cAMP-dependent type II regulatory subunit beta" P31323 7 107044705-107161811 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 135.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 110.2;Excitatory neurons: 146.3;Granulosa cells: 712.1;Theca cells: 271.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 70.7;Daudi: 99.8;K-562: 61.4;U-698: 254.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008421, HPA063879" Enhanced Uncertain Mitochondria NA NA 570000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA008421: AB_1855421, HPA063879: " "unprognostic (3.18e-1)" "unprognostic (2.48e-2)" "prognostic favorable (6.38e-4)" "unprognostic (1.63e-2)" "unprognostic (3.33e-3)" "unprognostic (2.43e-3)" "unprognostic (2.76e-1)" "unprognostic (8.14e-3)" "unprognostic (1.70e-1)" "unprognostic (5.97e-2)" "prognostic favorable (4.03e-4)" "unprognostic (1.50e-1)" "unprognostic (5.12e-3)" "unprognostic (2.39e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (8.74e-4)" "unprognostic (7.15e-2)" 135.8 44.9 10.7 4.8 12.1 14.2 51.3 5.7 17.5 8.0 5.3 11.1 3.6 6.9 4.4 11.2 7.0 4.9 15.5 13.2 9.5 8.8 2.5 7.6 3.8 6.2 10.2 26.4 8.7 6.5 11.4 15.1 8.3 9.2 6.9 7.5 9.9 4.4 1.5 3.7 11.5 5.1 6.9 16.7 9.1 13.6 7.8 2.6 3.5 6.1 4.0 20.3 6.2 10.1 0.1 1.5 9.1 70.7 36.8 0.0 0.1 3.6 11.5 3.0 2.7 0.0 0.2 99.8 0.8 2.3 8.6 0.1 7.1 0.0 5.5 2.8 7.9 33.3 0.1 0.0 10.3 0.6 4.5 0.5 0.0 0.3 0.0 3.1 42.9 5.4 61.4 2.9 0.1 7.5 14.0 0.4 17.3 0.0 2.8 4.0 0.2 0.0 0.1 0.1 11.6 16.7 5.4 1.2 3.9 22.9 2.1 7.0 24.4 3.5 9.2 0.0 7.1 2.1 0.1 254.8 2.5 17.5 33.9 0.6 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.1 0.2 0.3 0.0 0.6 10.7 12.1 5.7 17.5 13.2 9.5 6.2 10.2 8.3 6.9 7.8 10.1 39.6 3.2 1.5 9.8 1.9 2.4 1.6 2.1 0.6 33.5 27.9 10.5 35.9 12.8 5.1 7.3 10.4 0.1 3.7 1.7 0.0 2.5 7.9 1.8 16.2 17.4 0.0 110.2 146.3 0.0 0.6 17.5 3.6 0.9 4.5 712.1 19.2 0.0 1.6 5.0 71.9 1.9 4.1 19.6 26.4 8.5 29.8 64.1 17.8 15.9 17.0 6.4 3.1 60.8 10.9 0.1 2.1 53.0 2.0 3.5 0.0 0.8 5.4 11.9 19.7 5.4 57.7 2.5 6.5 0.7 2.4 0.0 3.7 271.7 2.7 4.6 PROS1 PROS ENSG00000184500 "Protein S" P07225 3 93873051-93980003 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "choroid plexus: 107.5;heart muscle: 116.6;liver: 283.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 83.1;Hepatocytes: 307.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 64.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 112.3;ASC TERT1: 100.1;HSkMC: 78.2;SK-MEL-30: 157.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007724, HPA023974, CAB032610" Approved "Secreted to blood" NA NA 22500000000 5000000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "CAB032610: AB_2237647, HPA007724: AB_1079688, HPA023974: AB_1855738" "unprognostic (2.00e-2)" "unprognostic (2.81e-2)" "unprognostic (9.21e-2)" "unprognostic (8.03e-3)" "unprognostic (3.35e-2)" "unprognostic (2.41e-1)" "unprognostic (6.48e-2)" "unprognostic (3.07e-1)" "unprognostic (5.18e-2)" "unprognostic (3.12e-1)" "unprognostic (1.10e-1)" "unprognostic (1.91e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (8.35e-4)" "unprognostic (4.90e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.42e-5)" 33.6 8.7 1.7 8.1 1.3 0.3 24.7 1.6 2.7 14.9 107.5 17.3 13.5 16.4 2.0 16.6 19.4 33.7 116.6 3.2 2.2 37.7 283.1 39.2 4.7 2.1 2.4 32.6 5.6 13.5 8.5 32.0 2.2 8.4 21.6 4.6 12.3 10.3 4.9 20.5 20.6 19.2 1.6 11.2 10.5 5.0 2.3 1.5 17.0 16.9 3.7 18.5 15.1 1.7 0.4 2.7 3.0 27.1 112.3 100.1 1.6 4.6 9.4 1.0 6.6 12.7 1.4 0.0 30.0 3.0 18.8 0.0 1.4 0.9 1.8 0.1 7.3 51.4 1.4 29.8 8.7 1.5 1.2 78.2 0.4 4.0 0.6 63.0 7.2 3.7 32.8 0.1 49.2 0.0 0.1 0.0 3.1 2.7 6.5 0.3 1.2 0.0 27.7 0.0 7.6 19.8 5.0 0.0 157.0 0.6 0.0 19.9 9.4 14.8 2.8 8.2 1.7 0.0 0.0 0.0 60.4 30.4 27.8 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.6 0.0 0.1 0.0 0.0 3.2 1.7 1.3 1.6 2.7 3.2 2.2 2.1 2.4 2.2 1.6 2.3 1.7 55.9 64.1 33.8 17.9 1.9 14.8 3.6 2.1 4.0 0.5 1.7 14.0 44.6 14.3 7.5 1.8 10.4 0.6 0.5 7.5 3.9 9.8 3.2 2.1 30.7 47.1 15.7 16.4 28.4 4.4 0.7 83.1 2.0 1.1 30.9 5.0 65.7 307.1 12.8 1.7 19.7 11.6 0.0 31.5 20.6 6.3 28.6 14.6 19.6 27.2 1.3 22.8 0.0 10.6 4.6 5.6 19.3 36.9 0.3 4.5 1.9 42.2 56.6 8.1 13.1 32.4 28.4 0.4 0.7 11.8 33.2 1.6 2.1 10.8 12.6 2.3 PRTG "FLJ25756, IGDCC5" ENSG00000166450 Protogenin Q2VWP7 15 55611544-55743152 "Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 10.4;thyroid gland: 10.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 191.8;Oligodendrocyte precursor cells: 51.8;Rod photoreceptor cells: 62.3" "Cancer enhanced" "Detected in some" "testis cancer: 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "AF22: 148.6;SuSa: 172.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA032138 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Vesicles, Plasma membrane" "HPA032138: AB_10669675" "unprognostic (2.80e-1)" "unprognostic (2.42e-2)" "unprognostic (1.32e-1)" "unprognostic (4.64e-2)" "unprognostic (2.07e-2)" "unprognostic (4.96e-4)" "unprognostic (1.82e-4)" "unprognostic (1.31e-1)" "unprognostic (3.19e-1)" "unprognostic (4.76e-3)" "unprognostic (1.37e-1)" "unprognostic (5.32e-2)" "unprognostic (5.67e-2)" "unprognostic (2.42e-6)" "unprognostic (8.81e-2)" "unprognostic (3.17e-2)" "unprognostic (2.70e-1)" 0.5 1.0 1.7 0.4 2.2 0.1 1.1 2.2 1.1 1.2 1.4 0.5 0.1 3.6 0.5 0.1 1.1 0.3 0.6 1.3 2.8 1.5 0.1 1.7 0.1 3.2 2.4 1.9 0.1 1.9 0.9 2.7 3.7 0.4 0.2 10.4 0.2 0.5 0.6 0.1 0.3 1.3 2.9 0.1 0.5 3.6 2.9 0.0 10.7 0.4 0.1 0.4 0.5 5.0 1.2 3.4 148.6 3.2 0.0 0.1 13.2 1.2 4.5 3.9 5.4 25.8 0.8 0.0 5.4 0.2 5.8 0.0 0.6 0.3 5.2 0.0 6.4 1.0 1.1 9.8 1.1 1.0 0.0 0.5 0.2 1.7 2.7 3.0 2.8 0.3 2.7 0.0 2.3 2.2 0.0 0.0 5.9 0.0 3.0 0.0 22.3 0.0 3.1 0.4 1.8 7.6 1.2 1.9 8.3 172.9 0.7 0.5 0.2 2.1 1.6 0.0 4.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 2.2 2.2 1.1 1.3 2.8 3.2 2.4 3.7 2.9 2.9 5.0 3.2 9.6 20.2 17.6 0.0 0.3 0.0 0.0 0.0 12.4 5.0 4.4 6.0 0.0 2.5 16.5 191.8 19.9 0.1 0.1 0.0 0.0 21.8 2.8 25.5 9.7 0.0 0.0 0.7 0.2 4.1 4.0 3.6 3.1 0.0 2.9 3.6 0.0 1.7 0.0 11.1 0.0 0.0 0.0 0.0 25.3 5.3 0.2 0.0 28.1 0.0 4.4 0.0 51.8 13.6 0.4 0.0 2.6 0.1 0.1 0.0 1.4 0.0 62.3 0.0 5.8 2.4 8.9 12.1 0.0 0.0 6.0 0.1 9.5 0.5 0.1 PTGDR2 "CD294, CRTH2, DP2, GPR44" ENSG00000183134 "Prostaglandin D2 receptor 2" Q9Y5Y4 11 60850933-60855950 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.2;intestine: 8.2;stomach 1: 9.3" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Endothelial cells: 2.2;Fibroblasts: 4.1;granulocytes: 4.5;Intestinal goblet cells: 2.0;Langerhans cells: 2.4;Smooth muscle cells: 6.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 178.1;eosinophil: 234.1" "Lineage enriched" "Detected in many" 7 "granulocytes: 234.1" "Cell line enhanced" "Detected in some" "HEL: 9.6;Hep G2: 4.8;HMC-1: 5.9;K-562: 4.0;MOLT-4: 3.1;NB-4: 14.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA014259 Uncertain NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA014259: AB_1849304" "unprognostic (9.77e-2)" "unprognostic (1.35e-3)" "unprognostic (5.45e-3)" "unprognostic (1.69e-1)" "unprognostic (1.90e-1)" "unprognostic (1.85e-3)" "unprognostic (1.70e-1)" "unprognostic (2.30e-4)" "unprognostic (2.61e-1)" "unprognostic (7.92e-2)" "unprognostic (8.68e-3)" "unprognostic (1.52e-1)" "unprognostic (1.32e-2)" "unprognostic (1.52e-1)" "unprognostic (3.31e-1)" "unprognostic (1.49e-1)" "unprognostic (4.99e-2)" 0.6 0.0 4.3 0.6 4.2 0.0 0.6 3.3 11.2 0.4 2.3 8.2 4.4 0.4 0.2 0.8 0.6 0.5 6.7 3.4 3.6 0.1 0.5 0.6 0.1 3.7 4.2 0.1 0.5 3.4 0.3 1.0 3.9 0.5 4.1 0.1 0.1 0.1 7.3 0.4 6.9 0.3 3.0 0.5 9.3 0.3 4.2 5.0 0.1 3.9 0.1 0.5 0.2 3.4 0.0 0.0 0.1 0.0 0.3 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 9.6 0.0 4.8 1.0 0.0 5.9 1.9 0.1 0.0 0.0 0.0 0.0 0.3 4.0 0.0 0.0 0.1 3.1 14.0 0.0 0.1 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 178.1 0.1 234.1 0.0 10.9 0.0 0.0 1.5 1.1 5.2 0.0 0.0 0.0 0.7 0.1 35.8 1.1 1.6 2.3 4.3 4.2 3.3 11.2 3.4 3.6 3.7 4.2 3.9 3.0 4.2 3.4 1.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.1 0.1 0.6 0.0 0.0 0.0 2.1 0.0 0.4 0.1 0.0 0.0 0.1 0.1 0.0 2.2 1.2 0.0 0.2 0.0 0.0 4.1 0.5 0.1 4.5 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 2.4 0.0 0.3 0.5 0.0 1.9 0.6 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.9 6.8 0.1 0.0 0.0 0.3 0.0 1.8 0.0 0.1 0.0 PTN "HBGF8, HBNF, NEGF1" ENSG00000105894 Pleiotrophin P21246 7 137227341-137343774 "Cancer-related genes, Predicted secreted proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 280.4;parathyroid gland: 383.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 672.0;Extravillous trophoblasts: 416.0;Horizontal cells: 526.6;Muller glia cells: 548.5;Oligodendrocyte precursor cells: 322.7;Squamous epithelial cells: 439.9" "Cancer enriched" "Detected in all" 11 "glioma: 514.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 12 "AF22: 1717.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017685, HPA073913" Enhanced Supported "Endoplasmic reticulum" "Secreted to blood" NA NA 167000 1400000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: NES - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" "Endoplasmic reticulum" "CAB017685: AB_1128556, HPA073913: " "unprognostic (1.51e-2)" "unprognostic (7.87e-2)" "unprognostic (5.44e-2)" "unprognostic (4.23e-2)" "unprognostic (1.92e-1)" "unprognostic (7.19e-2)" "unprognostic (2.81e-2)" "unprognostic (7.29e-2)" "unprognostic (1.30e-1)" "unprognostic (1.09e-2)" "unprognostic (3.86e-1)" "unprognostic (1.22e-2)" "prognostic favorable (1.35e-4)" "unprognostic (2.34e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (1.16e-2)" 26.2 18.2 212.9 4.1 206.4 0.1 82.3 217.0 280.4 100.0 182.0 31.4 5.4 76.8 55.3 78.2 19.2 55.9 87.7 209.6 205.2 38.4 8.5 18.4 7.4 220.3 200.5 19.0 8.4 383.5 126.1 36.2 196.3 116.1 21.6 63.4 37.4 52.5 2.2 9.1 10.1 54.0 204.2 40.4 15.7 53.8 207.6 21.4 18.9 18.8 11.4 24.8 65.1 209.1 1.2 0.0 1717.6 21.2 0.4 0.9 140.6 45.3 134.3 25.1 34.3 0.4 0.2 0.0 0.2 60.0 15.6 1.0 0.0 0.0 18.9 0.0 1.4 0.0 0.0 0.0 7.7 0.0 0.5 1.9 0.0 16.6 0.2 24.6 0.0 0.0 0.0 8.2 7.0 0.0 0.0 0.6 133.5 0.0 1.1 0.1 2.8 0.4 0.7 0.0 8.0 116.5 0.0 0.0 0.2 24.1 0.2 0.2 0.0 37.4 32.9 1.8 99.4 0.7 0.0 0.0 119.7 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 212.9 206.4 217.0 280.4 209.6 205.2 220.3 200.5 196.3 204.2 207.6 209.1 10.1 0.0 0.0 303.3 1.3 23.2 1.7 85.0 209.5 27.7 244.6 117.3 14.6 2.8 20.9 1.8 6.2 220.0 2.2 0.0 9.8 1.1 24.5 53.4 672.0 32.0 0.0 0.0 4.9 0.0 416.0 248.8 0.5 24.6 0.0 1.1 7.1 0.3 20.4 526.6 18.1 0.0 0.0 0.3 20.6 14.0 172.7 4.0 44.4 102.1 0.0 548.5 0.0 322.7 218.4 0.3 0.0 185.5 2.5 18.6 0.0 7.5 7.2 32.3 59.2 3.0 91.4 4.0 2.4 439.9 13.9 193.3 4.4 144.7 0.0 2.2 PYGL GSD6 ENSG00000100504 "Glycogen phosphorylase L" P06737 14 50857891-50944483 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 145.6" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 151.2;Hofbauer cells: 177.6;Muller glia cells: 265.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 141.1;neutrophil: 153.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 279.1;HMC-1: 304.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000962, HPA004119" Enhanced Supported "Plasma membrane,Cytosol" NA NA 16000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane, Cytosol" "HPA000962: AB_1079722, HPA004119: AB_1079723" "unprognostic (2.70e-2)" "unprognostic (8.64e-3)" "unprognostic (1.46e-2)" "unprognostic (8.55e-2)" "unprognostic (9.41e-2)" "prognostic unfavorable (5.97e-4)" "unprognostic (1.66e-1)" "unprognostic (1.34e-2)" "unprognostic (3.34e-1)" "unprognostic (1.94e-2)" "prognostic unfavorable (2.63e-4)" "unprognostic (4.45e-3)" "unprognostic (3.15e-3)" "unprognostic (1.95e-2)" "unprognostic (1.76e-1)" "unprognostic (9.72e-2)" "unprognostic (1.12e-3)" 110.1 21.0 5.9 24.1 6.6 108.9 36.4 5.0 8.4 33.6 10.4 19.0 3.7 20.7 6.4 55.8 19.1 13.0 14.9 5.2 6.2 10.2 145.6 26.1 6.3 10.7 17.6 18.2 5.7 21.1 7.5 49.3 8.7 13.0 24.0 78.2 26.8 29.7 5.1 37.0 8.4 26.7 8.6 49.4 9.6 5.2 9.0 4.8 10.2 5.8 6.8 41.7 38.1 10.3 145.7 40.8 10.1 64.3 47.0 56.2 114.5 28.6 24.1 77.4 117.3 107.4 18.3 0.1 54.4 171.7 91.2 279.1 107.0 144.8 132.0 0.5 46.8 28.0 60.5 82.4 83.8 106.9 304.4 119.4 56.8 104.1 43.6 75.4 69.3 0.8 11.6 0.5 55.4 144.7 0.4 141.7 39.3 12.8 152.0 2.7 36.2 6.1 104.7 95.1 4.5 4.4 131.0 43.3 1.7 38.6 20.6 200.4 3.2 29.7 49.6 56.0 92.9 1.2 0.3 0.5 27.3 107.7 15.9 50.2 55.9 141.1 0.0 24.2 0.0 0.0 0.0 0.0 27.3 0.0 0.0 0.0 153.7 0.6 15.7 1.2 0.2 24.8 5.9 6.6 5.0 8.4 5.2 6.2 10.7 17.6 8.7 8.6 9.0 10.3 6.7 22.4 6.3 1.3 1.8 30.7 10.5 40.5 6.8 4.6 7.0 3.8 3.4 5.7 35.4 7.3 0.0 28.9 0.2 11.2 3.9 10.9 1.0 35.4 18.9 7.8 1.2 9.0 1.8 2.1 151.2 18.8 6.6 62.6 6.3 9.3 8.2 65.4 177.6 1.7 2.2 7.1 14.2 56.7 7.9 1.5 14.3 54.6 19.6 15.9 52.4 265.1 2.1 14.1 0.6 7.4 5.2 21.8 1.8 9.7 0.0 6.4 24.5 11.9 6.6 15.4 8.8 0.7 1.4 22.4 22.3 21.1 2.3 4.0 14.0 9.2 RAB25 CATX-8 ENSG00000132698 "RAB25, member RAS oncogene family" P57735 1 156061160-156070504 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 423.3;skin 1: 210.0" "Cell type enhanced" "Detected in many" "Paneth cells: 249.6;Squamous epithelial cells: 300.6;Undifferentiated cells: 244.6;Urothelial cells: 232.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 1.3" "Lineage enriched" "Detected in single" 13 "T-cells: 1.3" "Cell line enhanced" "Detected in some" "BEWO: 120.9;CAPAN-2: 119.9;MCF7: 171.5;OE19: 392.3;RT4: 153.4;SK-BR-3: 243.3;T-47d: 227.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010872, CAB033645" Enhanced Uncertain "Cell Junctions,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions, Cytosol" "CAB033645: AB_1128883, HPA010872: AB_1079729" "unprognostic (2.43e-1)" "unprognostic (4.57e-1)" "unprognostic (2.24e-1)" "unprognostic (1.71e-1)" "unprognostic (2.64e-1)" "unprognostic (1.97e-1)" "unprognostic (4.27e-2)" "unprognostic (4.63e-2)" "unprognostic (2.82e-1)" "unprognostic (2.03e-2)" "unprognostic (1.22e-2)" "unprognostic (1.39e-1)" "prognostic favorable (1.38e-6)" "unprognostic (2.31e-2)" "unprognostic (3.24e-2)" "unprognostic (3.14e-2)" "unprognostic (4.94e-2)" 0.6 0.1 0.1 10.2 0.1 0.1 52.0 0.3 0.3 76.2 0.0 86.2 72.9 7.3 37.5 423.3 47.5 26.4 0.1 0.0 0.0 41.6 1.7 39.2 0.4 0.1 0.1 0.4 57.1 68.9 27.5 12.4 0.1 36.3 78.1 0.0 105.3 28.4 0.9 210.0 65.6 3.7 0.2 0.2 80.9 0.3 0.1 10.1 50.6 0.0 44.0 69.9 148.2 0.3 93.3 0.0 0.0 0.0 0.0 0.0 120.9 0.0 0.0 0.0 0.0 90.4 119.9 0.0 0.1 0.0 0.0 109.5 0.0 51.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 105.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 171.5 0.0 0.4 4.8 392.3 0.0 0.1 0.0 0.3 0.0 153.4 13.3 0.0 0.0 243.3 0.3 21.1 227.9 0.4 0.0 0.2 0.2 0.0 0.2 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.0 0.2 0.0 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.1 0.3 0.3 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.3 1.2 28.9 41.0 0.0 1.5 55.1 102.9 113.9 74.0 0.0 121.4 137.7 0.1 94.4 98.7 86.5 0.0 102.1 2.3 197.8 166.3 170.4 0.0 58.6 6.4 2.6 85.4 0.0 0.1 150.3 30.0 2.3 96.4 66.2 5.7 0.0 0.0 0.4 7.3 0.0 0.1 208.5 89.5 0.0 5.8 0.0 0.3 2.1 21.4 0.0 3.6 0.0 0.0 0.0 0.1 197.3 249.6 0.0 0.3 114.0 195.9 35.5 66.3 0.0 0.0 0.0 6.8 0.2 1.1 300.6 154.7 80.3 2.7 0.0 244.6 232.3 RAB26 ENSG00000167964 "RAB26, member RAS oncogene family" Q9ULW5 16 2140803-2154165 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.9;choroid plexus: 43.0;liver: 45.9;pancreas: 42.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 36.1;Enteroendocrine cells: 99.4;Excitatory neurons: 52.0;Inhibitory neurons: 28.3;Intestinal goblet cells: 41.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 20.1;HeLa: 23.2;MCF7: 13.5;SCLC-21H: 27.2;SK-BR-3: 24.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075624 Uncertain "Vesicles,Plasma membrane,Centrosome" "Intracellular and membrane" No No "Cluster 22: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Vesicles, Plasma membrane" Centrosome "HPA075624: " "unprognostic (1.01e-2)" "prognostic favorable (8.20e-5)" "unprognostic (7.25e-2)" "unprognostic (1.52e-1)" "unprognostic (7.34e-2)" "unprognostic (9.41e-3)" "unprognostic (2.81e-2)" "unprognostic (5.10e-2)" "unprognostic (1.82e-2)" "unprognostic (3.55e-2)" "unprognostic (3.75e-2)" "unprognostic (2.14e-1)" "unprognostic (6.48e-2)" "unprognostic (5.68e-2)" "unprognostic (1.23e-1)" "unprognostic (7.16e-2)" "unprognostic (2.92e-3)" 0.3 1.1 53.5 0.1 55.8 0.2 0.9 57.7 84.9 1.7 43.0 5.7 5.6 0.2 1.8 1.6 0.6 0.8 1.8 60.7 46.2 1.4 45.9 0.3 0.3 48.0 45.4 0.2 42.7 3.4 34.0 0.0 49.1 4.9 5.1 6.8 18.4 0.8 1.1 1.5 6.4 0.1 44.0 0.7 13.7 1.0 47.6 0.3 1.7 2.1 0.8 0.8 0.7 51.9 1.7 20.1 0.1 5.1 0.3 0.1 0.1 0.9 1.6 0.7 1.3 0.6 4.0 0.3 1.4 1.3 0.6 3.2 1.1 0.4 0.1 2.2 2.1 0.8 23.2 1.8 0.8 0.0 0.6 0.8 0.2 0.2 0.3 4.6 0.4 3.2 0.4 0.0 2.3 13.5 0.1 1.0 1.2 6.5 1.8 1.7 1.6 3.5 7.7 1.4 27.2 5.4 0.6 24.9 1.0 0.3 8.2 0.3 0.9 0.0 3.5 0.4 0.4 2.9 0.1 0.3 0.5 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 53.5 55.8 57.7 84.9 60.7 46.2 48.0 45.4 49.1 44.0 47.6 51.9 0.2 0.0 1.1 6.5 1.3 1.3 1.6 1.4 8.0 36.1 1.4 1.4 1.6 1.5 3.4 0.0 4.2 0.0 0.0 2.6 0.0 0.4 0.1 1.0 0.3 0.4 99.4 0.0 52.0 1.0 0.0 0.4 12.8 0.4 0.0 0.5 1.1 8.1 0.2 1.7 28.3 41.9 4.1 0.3 0.0 0.1 0.0 0.1 3.6 8.4 0.0 10.7 0.0 20.1 3.6 0.5 1.8 0.0 3.8 1.5 10.5 0.6 2.3 9.1 0.0 0.3 0.3 0.0 2.4 1.5 0.1 0.1 0.2 0.3 3.2 2.6 RAC3 ENSG00000169750 "Rac family small GTPase 3" P60763 17 82031678-82034204 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 45.0;Extravillous trophoblasts: 152.1;Spermatogonia: 58.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "CACO-2: 230.8;HEK 293: 274.7;NB-4: 156.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047820 Uncertain NA NA "Cluster 35: T-regs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA047820: AB_2680167" "unprognostic (3.48e-2)" "unprognostic (2.26e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (6.21e-5)" "unprognostic (1.62e-1)" "unprognostic (1.39e-1)" "unprognostic (1.43e-2)" "unprognostic (3.36e-2)" "unprognostic (1.57e-1)" "unprognostic (6.62e-2)" "unprognostic (1.22e-2)" "unprognostic (3.67e-1)" "unprognostic (4.39e-2)" "unprognostic (1.62e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (4.69e-4)" "unprognostic (1.25e-3)" 12.3 5.0 22.8 1.8 20.8 7.7 13.7 26.3 29.5 5.3 9.3 4.8 3.4 2.8 7.3 10.9 3.8 3.0 3.0 19.7 24.5 9.4 20.7 4.0 1.7 23.3 22.3 4.8 4.7 9.3 22.8 5.6 27.0 11.1 1.4 2.8 18.1 4.2 0.8 12.4 3.7 1.3 15.3 1.9 11.8 28.1 26.5 2.2 9.8 0.2 1.5 3.1 7.6 20.6 11.1 15.1 45.6 63.1 9.7 18.2 50.5 7.8 7.2 26.1 22.3 230.8 21.4 5.8 11.5 4.8 1.7 15.6 43.0 17.8 4.1 3.6 274.7 64.6 20.2 16.7 47.0 28.0 12.2 27.5 13.0 3.5 12.0 19.5 60.3 33.8 103.1 30.2 10.8 35.6 7.3 156.4 61.4 39.2 27.6 47.6 4.5 27.7 20.0 5.4 109.8 111.5 4.1 57.2 55.7 16.1 58.6 40.7 21.6 10.8 9.8 5.5 12.1 14.6 9.9 4.4 6.6 17.3 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 22.8 20.8 26.3 29.5 19.7 24.5 23.3 22.3 27.0 15.3 26.5 20.6 1.6 0.0 0.0 2.3 0.9 8.7 16.3 12.2 19.9 5.3 36.9 45.0 0.2 4.3 3.6 5.5 0.0 30.0 1.8 3.3 21.5 9.8 19.1 5.9 5.4 2.3 3.0 6.9 5.2 3.3 152.1 10.7 8.2 12.6 4.5 17.8 1.4 11.3 9.7 6.7 8.3 5.1 22.4 0.0 2.6 16.6 5.6 0.9 14.2 0.0 2.0 6.0 0.0 3.5 2.0 5.5 2.4 1.9 2.6 16.4 4.2 26.0 2.4 7.3 0.0 0.8 5.3 2.2 58.0 15.8 7.5 14.1 3.1 8.6 5.2 8.4 RALGPS2 "FLJ10244, FLJ25604, KIAA0351" ENSG00000116191 "Ral GEF with PH domain and SH3 binding motif 2" Q86X27 1 178725147-178921841 "Disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Alzheimer disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 56.2;testis: 77.0" "Cell type enhanced" "Detected in many" "B-cells: 263.1;Cone photoreceptor cells: 206.4;Late spermatids: 185.9;Rod photoreceptor cells: 397.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "memory B-cell: 26.7;naive B-cell: 21.0" "Lineage enriched" "Detected in many" 11 "B-cells: 26.7" "Cell line enhanced" "Detected in many" "U-266/84: 250.4;U-698: 194.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027143, HPA028328" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Cytosol" "HPA027143: AB_10602071, HPA028328: AB_10601889" "unprognostic (8.13e-2)" "unprognostic (1.46e-2)" "unprognostic (4.06e-3)" "unprognostic (2.71e-1)" "unprognostic (1.23e-1)" "unprognostic (1.50e-1)" "unprognostic (5.72e-2)" "unprognostic (6.63e-3)" "unprognostic (4.07e-2)" "unprognostic (1.33e-1)" "unprognostic (2.82e-2)" "unprognostic (7.77e-2)" "unprognostic (1.55e-1)" "unprognostic (3.45e-1)" "unprognostic (6.35e-2)" "unprognostic (4.37e-2)" "unprognostic (8.97e-2)" 5.5 8.5 3.5 24.0 5.0 13.2 8.1 4.9 4.6 6.5 3.3 13.4 11.5 9.4 5.4 16.3 8.0 8.1 4.6 7.1 5.8 6.7 32.0 2.8 52.4 3.0 2.4 18.3 5.7 7.8 2.9 9.2 2.6 7.3 12.1 52.5 5.4 5.5 1.4 19.6 16.4 11.8 3.4 28.3 13.7 77.0 5.5 15.2 6.8 4.8 56.2 12.6 7.6 2.1 39.9 12.7 38.7 0.4 42.3 61.6 15.2 34.0 74.8 27.1 24.3 15.1 38.3 83.7 11.2 100.8 13.5 32.2 17.2 8.6 35.4 0.1 10.3 0.0 8.7 14.6 7.1 11.1 0.4 27.5 7.5 35.1 24.6 18.8 23.7 15.3 20.6 3.1 17.8 6.3 17.0 3.5 26.5 15.3 13.4 23.5 39.9 0.7 9.3 24.9 6.0 17.2 22.2 24.5 48.4 26.3 29.3 5.6 17.9 12.4 11.8 45.4 16.4 91.8 250.4 194.3 7.2 5.7 14.2 0.8 0.1 2.4 0.3 0.1 0.3 26.7 0.2 0.1 0.4 21.0 0.7 0.2 1.3 0.4 0.1 0.8 0.0 1.1 3.5 5.0 4.9 4.6 7.1 5.8 3.0 2.4 2.6 3.4 5.5 2.1 5.4 12.8 6.9 29.4 263.1 14.8 16.3 5.4 14.8 97.4 27.9 15.1 17.5 15.7 8.7 14.7 206.4 7.5 11.6 39.5 21.5 15.2 123.0 23.3 25.6 4.9 35.9 22.7 84.0 12.0 10.1 18.7 48.9 33.0 8.8 60.3 2.9 55.2 6.3 13.5 92.3 22.5 0.0 8.5 4.8 185.9 50.1 7.3 8.8 41.2 5.1 27.8 10.3 107.5 4.0 31.0 52.4 46.6 105.2 26.0 22.7 9.7 23.9 397.3 19.7 41.5 18.6 146.6 34.8 29.1 34.1 3.3 10.3 20.7 15.6 72.0 RAMP3 ENSG00000122679 "Receptor activity modifying protein 3" O60896 7 45157791-45186302 "FDA approved drug targets, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 144.6" "Group enriched" "Detected in many" 12 "Adipocytes: 287.8;Endothelial cells: 366.0;Hepatic stellate cells: 555.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "Karpas-707: 2.5" "Group enriched" "Detected in all" 4 "cerebellum: 62.2;cerebral cortex: 49.2;thalamus: 174.9;white matter: 60.0" "Low region specificity" "Detected in all" HPA075527 Supported "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA075527: " "unprognostic (1.62e-3)" "prognostic favorable (2.89e-4)" "unprognostic (4.85e-2)" "unprognostic (6.88e-3)" "unprognostic (3.68e-2)" "unprognostic (1.44e-3)" "prognostic favorable (2.50e-6)" "unprognostic (1.14e-1)" "unprognostic (2.35e-1)" "unprognostic (3.19e-1)" "unprognostic (2.79e-2)" "unprognostic (9.49e-2)" "unprognostic (1.09e-2)" "unprognostic (1.20e-2)" "unprognostic (2.43e-1)" "unprognostic (1.91e-1)" "unprognostic (9.21e-2)" 86.9 32.6 17.7 23.0 19.7 0.2 71.7 26.9 22.7 33.5 21.3 24.4 10.2 25.9 3.9 18.9 22.8 28.7 91.3 19.2 25.8 84.1 23.9 144.6 55.0 37.3 25.7 7.4 19.7 28.1 22.3 8.6 34.2 29.7 8.6 1.1 22.1 12.9 19.3 22.8 30.0 24.4 31.6 11.4 25.7 6.3 23.5 7.3 71.9 26.9 30.3 28.5 30.5 42.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 17.7 19.7 26.9 22.7 19.2 25.8 37.3 25.7 34.2 31.6 23.5 42.4 287.8 0.0 1.9 0.3 3.6 16.3 0.3 0.0 2.2 0.6 5.9 2.8 8.7 1.5 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.1 20.8 0.4 7.3 366.0 0.0 13.5 3.5 0.7 0.1 10.7 0.0 0.2 0.0 0.0 555.4 7.3 0.5 0.0 0.2 0.0 0.0 31.2 19.1 6.7 1.2 1.3 26.6 5.6 0.0 0.2 0.0 0.0 6.5 0.0 0.0 1.2 1.3 0.6 0.0 0.0 0.0 0.5 0.0 2.8 4.9 0.3 0.9 0.9 14.5 0.0 1.7 1.5 0.0 0.5 RANBP3L FLJ25422 ENSG00000164188 "RAN binding protein 3 like" Q86VV4 5 36246913-36302114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.9;kidney: 24.6" "Cell type enriched" "Detected in some" 7 "Astrocytes: 355.9" "Group enriched" "Detected in some" 5 "breast cancer: 1.4;glioma: 3.7;prostate cancer: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "ASC diff: 12.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA037471, HPA037472, HPA061526" Approved Uncertain Nucleoplasm NA NA "Cluster 65: Brain - Ion transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA037471: AB_10671756, HPA037472: AB_2675489, HPA061526: AB_2684552" "unprognostic (1.19e-1)" "unprognostic (1.02e-1)" "unprognostic (1.27e-1)" "unprognostic (1.41e-3)" "unprognostic (5.52e-3)" "unprognostic (2.85e-1)" "unprognostic (2.35e-3)" "unprognostic (1.08e-2)" "unprognostic (9.56e-2)" "unprognostic (2.66e-1)" "unprognostic (2.81e-1)" "unprognostic (1.28e-1)" "unprognostic (3.76e-4)" "unprognostic (1.68e-2)" "unprognostic (9.13e-2)" "unprognostic (8.87e-3)" "unprognostic (5.71e-2)" 3.8 1.7 25.2 0.3 27.0 0.0 7.6 4.6 29.9 1.2 5.4 0.8 0.2 0.7 1.8 0.5 1.2 1.8 1.5 25.1 12.2 24.6 9.9 2.0 0.2 9.9 18.9 2.1 0.4 0.2 2.9 5.0 7.4 13.5 0.4 5.3 0.6 2.9 0.4 0.4 0.4 0.6 12.6 0.2 1.8 4.7 18.6 0.1 2.2 2.9 0.6 6.9 0.8 15.2 0.0 0.0 0.1 0.2 12.1 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.2 27.0 4.6 29.9 25.1 12.2 9.9 18.9 7.4 12.6 18.6 15.2 0.3 0.0 0.0 355.9 0.0 0.0 0.1 0.0 0.6 0.4 4.1 2.3 0.3 0.0 0.0 9.2 0.0 0.0 1.3 0.0 46.9 0.0 0.1 0.1 0.7 0.4 0.0 0.0 5.1 0.0 0.0 1.5 0.0 0.0 0.0 0.2 0.4 1.3 1.9 0.0 4.5 0.0 0.0 0.0 0.3 0.8 2.1 0.2 1.8 23.4 0.0 16.1 0.0 5.5 2.8 0.0 0.0 2.2 0.0 1.3 0.0 0.2 0.0 0.6 13.1 0.6 8.3 0.0 0.1 0.0 0.0 0.1 0.0 3.0 0.0 0.1 RAP2C DKFZp313B211 ENSG00000123728 "RAP2C, member of RAS oncogene family" Q9Y3L5 X 132203024-132219480 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 92.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (1.37e-2)" "unprognostic (8.80e-2)" "unprognostic (6.66e-2)" "unprognostic (1.54e-2)" "unprognostic (8.63e-2)" "unprognostic (4.14e-2)" "unprognostic (4.95e-2)" "unprognostic (3.44e-1)" "unprognostic (1.44e-1)" "unprognostic (1.21e-2)" "unprognostic (1.51e-2)" "unprognostic (3.04e-2)" "prognostic unfavorable (3.81e-5)" "unprognostic (2.27e-1)" "unprognostic (1.45e-1)" "unprognostic (2.44e-2)" "unprognostic (1.00e-1)" 16.2 16.5 8.2 19.7 8.2 52.7 11.6 7.6 11.0 11.5 7.3 12.1 17.1 92.1 30.7 16.5 18.8 13.1 13.1 7.4 8.1 21.5 46.9 14.8 26.2 9.6 8.2 11.6 12.7 7.7 5.3 20.9 8.6 11.1 14.1 5.9 11.2 12.3 24.3 15.3 14.9 55.2 8.9 20.3 14.0 7.1 9.4 20.8 9.0 16.1 25.6 15.3 12.8 8.6 20.9 17.1 24.7 27.0 20.8 33.2 35.4 23.9 30.6 23.6 23.9 15.9 25.2 31.1 36.9 27.2 21.3 15.9 23.0 24.2 30.6 54.3 20.2 23.8 19.7 24.3 31.6 39.7 31.9 26.9 27.3 26.2 27.9 24.0 26.6 17.6 19.1 29.9 26.1 33.6 23.0 32.2 16.9 22.0 22.9 16.9 18.8 31.1 31.3 14.3 4.9 26.2 13.7 17.4 26.8 38.2 28.2 22.0 20.9 23.9 13.0 48.2 44.9 28.0 24.2 29.5 26.9 38.6 21.4 6.8 3.9 10.7 4.6 8.9 5.6 4.7 5.4 4.9 4.4 3.6 5.0 5.9 8.1 6.8 14.4 2.2 6.1 3.6 8.2 8.2 7.6 11.0 7.4 8.1 9.6 8.2 8.6 8.9 9.4 8.6 13.7 9.6 9.7 8.8 39.9 32.2 16.6 11.8 17.6 5.9 13.5 7.6 20.5 8.6 8.4 22.0 4.2 33.6 45.0 25.2 76.3 10.1 0.4 14.5 13.0 15.5 5.4 9.5 4.0 13.2 37.7 17.5 20.4 17.8 13.3 8.6 16.1 46.3 24.6 8.4 4.2 9.6 20.3 37.7 53.2 2.2 20.2 36.1 32.0 13.1 24.9 22.7 29.9 7.5 6.8 20.7 17.4 15.1 28.0 16.8 20.3 18.2 11.5 6.4 6.6 13.2 14.9 4.9 3.7 29.6 32.8 74.6 34.5 14.2 11.4 21.1 RASAL3 FLJ21438 ENSG00000105122 "RAS protein activator like 3" Q86YV0 19 15451624-15464544 "Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 23.5;intestine: 19.8;lung: 10.6;lymphoid tissue: 39.4" "Cell type enhanced" "Detected in many" "B-cells: 39.4;dendritic cells: 70.9;granulocytes: 39.3;NK-cells: 139.0;T-cells: 76.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 30.6;HEL: 25.5;HMC-1: 46.7;Karpas-707: 52.5;NB-4: 27.8;RPMI-8226: 23.5;TIME: 35.5;U-937: 34.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA043417 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Plasma membrane" "HPA043417: AB_2678473" "unprognostic (2.72e-2)" "prognostic favorable (8.75e-4)" "unprognostic (3.27e-2)" "prognostic favorable (3.58e-5)" "unprognostic (2.31e-1)" "prognostic favorable (3.07e-4)" "unprognostic (1.82e-2)" "unprognostic (6.21e-3)" "unprognostic (7.40e-3)" "unprognostic (1.02e-1)" "unprognostic (3.49e-2)" "unprognostic (3.32e-1)" "prognostic unfavorable (1.16e-6)" "unprognostic (2.98e-1)" "unprognostic (1.90e-2)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" 3.7 2.6 2.8 17.3 2.9 23.5 1.9 3.1 3.6 1.8 2.9 4.2 4.5 1.5 0.7 2.8 2.2 3.6 1.4 2.9 3.2 3.7 3.6 10.6 32.8 4.2 3.3 0.9 1.4 1.2 1.5 1.0 3.9 2.8 2.3 0.1 3.5 0.9 0.7 1.5 19.8 1.2 4.1 39.4 5.4 0.5 4.2 23.8 3.8 0.4 19.4 4.2 2.3 5.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 6.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 30.6 0.0 25.5 0.0 0.0 0.4 20.4 46.7 0.1 0.0 0.0 0.0 0.0 0.2 8.0 0.0 52.5 0.0 0.4 10.9 27.8 0.0 0.0 0.0 3.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 8.7 35.5 0.0 0.0 0.0 0.0 0.4 10.1 15.1 0.0 34.1 0.1 6.4 2.3 12.9 18.4 4.7 10.7 3.1 11.7 20.4 3.4 3.5 9.7 11.8 3.4 12.4 12.8 4.2 9.2 5.5 2.8 2.9 3.1 3.6 2.9 3.2 4.2 3.3 3.9 4.1 4.2 5.2 4.1 3.2 5.6 0.0 39.4 0.3 0.0 0.3 0.0 0.0 2.0 2.2 2.5 2.8 1.4 0.0 0.0 0.2 70.9 0.0 0.0 0.2 0.7 5.4 0.4 5.4 0.0 7.4 0.1 0.6 0.2 1.0 2.6 0.4 39.3 0.0 3.9 4.6 11.3 0.0 0.1 0.0 0.0 11.6 3.5 1.7 0.0 17.2 0.0 13.1 14.2 0.1 139.0 0.5 0.1 0.2 0.0 1.2 23.7 0.2 0.0 1.5 5.7 0.1 0.0 0.5 1.5 0.4 0.6 0.3 0.6 0.4 76.7 1.0 0.2 0.1 RASGRP1 "CalDAG-GEFII, RASGRP" ENSG00000172575 "RAS guanyl releasing protein 1" O95267 15 38488103-38565575 "Disease related genes, Predicted intracellular proteins, RAS pathway related proteins" Differentiation "Guanine-nucleotide releasing factor" "Disease variant, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.7;lymphoid tissue: 45.7;retina: 29.7" "Cell type enhanced" "Detected in many" "dendritic cells: 71.4;Excitatory neurons: 54.1;Muller glia cells: 86.9;Plasma cells: 43.0;T-cells: 84.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 10.3" "Lineage enriched" "Detected in many" 4 "T-cells: 10.3" "Group enriched" "Detected in many" 4 "HDLM-2: 54.5;JURKAT: 70.2;MOLT-4: 52.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039389 Supported "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Plasma membrane" "HPA039389: AB_2732481" "unprognostic (3.44e-3)" "unprognostic (1.86e-2)" "unprognostic (1.17e-2)" "unprognostic (3.43e-3)" "unprognostic (1.82e-2)" "unprognostic (3.33e-3)" "unprognostic (9.63e-2)" "unprognostic (4.23e-2)" "unprognostic (1.91e-1)" "unprognostic (1.21e-1)" "unprognostic (4.50e-1)" "unprognostic (3.01e-2)" "unprognostic (2.54e-1)" "unprognostic (2.55e-1)" "unprognostic (1.51e-1)" "unprognostic (3.40e-1)" "unprognostic (9.30e-2)" 1.1 0.8 6.7 10.5 16.8 8.5 1.7 23.7 13.2 0.8 0.0 1.4 2.4 1.4 0.4 5.9 4.4 2.5 1.2 11.6 3.3 5.5 1.1 4.1 21.4 15.3 2.5 0.4 1.8 0.5 0.5 0.9 17.9 0.7 2.1 29.7 1.7 0.7 0.4 6.9 3.6 0.6 0.0 8.9 4.5 2.0 8.8 45.7 0.6 0.7 16.4 3.4 2.0 9.2 0.0 0.4 1.0 0.3 0.0 0.0 0.1 4.1 1.2 2.0 1.7 4.5 0.0 11.6 0.9 0.1 0.2 0.2 2.4 0.0 1.9 54.5 2.2 0.9 0.5 0.0 0.6 0.5 0.8 0.0 0.1 1.1 0.0 0.0 0.0 70.2 0.5 3.6 0.0 1.7 52.3 0.1 0.7 0.0 0.0 14.4 0.3 0.0 2.0 0.1 4.7 1.7 2.6 0.1 0.2 1.5 1.2 0.0 0.2 0.4 1.6 5.6 0.8 8.7 4.6 13.6 0.2 0.1 0.6 0.0 0.0 0.9 5.2 0.0 3.7 1.1 5.7 5.2 0.0 0.6 5.2 5.3 0.2 2.4 0.0 0.0 10.3 1.4 6.7 16.8 23.7 13.2 11.6 3.3 15.3 2.5 17.9 0.0 8.8 9.2 0.9 6.4 10.7 6.5 26.5 2.4 0.4 6.8 4.6 9.6 3.4 2.0 4.5 5.7 2.7 33.1 10.4 0.3 71.4 0.1 3.9 18.4 1.5 7.6 1.6 0.8 0.0 0.0 54.1 10.0 0.2 1.2 1.1 6.6 3.8 0.4 1.1 0.5 0.7 6.7 16.5 1.3 0.0 0.8 6.1 0.7 0.0 3.0 7.2 9.4 3.0 86.9 34.0 2.5 3.9 34.1 0.0 0.0 43.0 0.7 0.3 7.8 0.4 21.3 0.0 1.9 1.3 1.2 3.8 4.0 8.2 0.0 84.7 0.3 0.9 0.5 RASIP1 "FLJ20401, RAIN" ENSG00000105538 "Ras interacting protein 1" Q5U651 19 48720585-48740610 "Predicted intracellular proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 121.8;Endothelial cells: 83.9;Hepatic stellate cells: 94.2;Theca cells: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 14.7;HeLa: 13.9;HUVEC TERT2: 38.5;SiHa: 21.1;TIME: 52.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077251 Approved NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA077251: AB_2732337" "unprognostic (9.98e-2)" "unprognostic (2.46e-1)" "unprognostic (1.32e-1)" "unprognostic (2.00e-1)" "unprognostic (3.64e-2)" "prognostic favorable (7.17e-5)" "unprognostic (8.44e-2)" "unprognostic (2.63e-1)" "unprognostic (3.10e-2)" "unprognostic (1.18e-1)" "prognostic favorable (9.46e-4)" "unprognostic (5.65e-2)" "unprognostic (1.55e-1)" "unprognostic (1.43e-2)" "unprognostic (1.32e-1)" "unprognostic (2.90e-1)" "unprognostic (1.19e-1)" 24.4 7.0 5.9 2.6 4.3 0.7 21.0 4.4 4.6 9.2 1.4 5.6 2.5 11.2 1.1 5.1 9.9 3.8 18.8 3.6 4.0 12.6 2.6 27.9 2.2 4.9 5.3 4.9 13.2 1.6 4.1 7.9 5.9 5.5 0.7 0.1 4.8 2.7 7.7 6.0 5.7 4.2 4.5 16.8 10.3 6.8 7.3 1.5 10.5 4.0 1.4 7.6 7.7 3.6 10.2 0.1 0.2 0.2 0.0 0.0 0.2 0.5 0.0 0.0 0.0 1.6 1.1 0.8 2.2 0.0 0.0 2.5 0.2 2.2 0.0 0.0 14.7 0.2 13.9 0.4 2.2 0.0 0.7 2.2 1.2 0.0 0.0 0.0 38.5 1.3 1.3 0.1 0.0 0.9 0.0 1.3 0.3 0.4 0.0 0.2 0.0 0.4 0.0 0.8 6.7 0.5 21.1 0.0 0.0 0.1 0.1 0.0 52.4 0.0 0.4 0.2 0.0 0.6 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 4.3 4.4 4.6 3.6 4.0 4.9 5.3 5.9 4.5 7.3 3.6 121.8 0.0 1.3 0.0 1.2 6.5 5.7 2.0 0.6 1.1 5.9 10.8 7.3 1.5 1.2 1.8 0.0 0.4 0.7 0.1 0.0 0.7 5.9 3.2 4.8 83.9 0.0 2.7 3.4 0.7 1.9 9.5 2.0 3.8 0.0 6.0 94.2 1.9 0.7 6.7 1.1 0.1 4.1 6.3 3.0 5.2 10.2 1.0 19.6 16.9 0.0 2.1 0.0 1.5 1.5 0.8 0.0 11.3 1.4 10.1 0.2 0.3 2.1 0.7 19.7 1.9 6.2 1.0 11.0 3.7 6.0 0.3 1.0 40.2 0.2 6.4 RDH16 "RODH-4, SDR9C8" ENSG00000139547 "Retinol dehydrogenase 16" O75452 12 56951431-56959374 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 152 "liver: 793.0" "Cell type enriched" "Detected in some" 27 "Hepatocytes: 365.1" "Cancer enriched" "Detected in many" 20 "liver cancer: 44.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 2.0;hTCEpi: 4.3;OE19: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA038518 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 62: Liver - Hemostasis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 2: Hepatocytes - Metabolism" "HPA038518: AB_10672713" "unprognostic (5.42e-3)" "unprognostic (4.20e-2)" "unprognostic (2.99e-2)" "unprognostic (1.14e-1)" "unprognostic (1.88e-1)" "unprognostic (2.92e-2)" "prognostic favorable (2.16e-5)" "unprognostic (8.83e-3)" "unprognostic (1.04e-1)" "unprognostic (2.84e-1)" "unprognostic (6.85e-2)" "unprognostic (6.10e-1)" "unprognostic (7.99e-12)" "unprognostic (2.24e-1)" "unprognostic (1.29e-2)" "unprognostic (1.62e-1)" "unprognostic (2.01e-2)" 0.3 0.3 0.9 0.0 0.9 0.0 0.3 0.9 1.1 1.2 0.9 0.3 0.0 0.4 0.1 1.4 0.5 0.0 0.4 0.9 0.8 0.5 793.0 0.4 0.1 0.8 0.8 0.5 0.6 0.0 0.3 0.0 0.9 5.2 0.0 0.4 0.5 2.4 0.2 2.9 0.5 0.0 0.8 2.5 0.3 1.3 0.8 0.2 0.3 0.0 1.3 0.3 1.6 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 4.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 1.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.9 1.1 0.9 0.8 0.8 0.8 0.9 0.8 0.8 0.9 0.1 0.0 0.0 2.0 1.9 0.0 1.2 0.3 0.0 2.2 0.2 0.0 2.0 5.7 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.1 8.5 0.1 0.1 0.6 0.0 13.5 0.2 0.4 0.0 0.3 0.0 0.1 0.0 0.3 3.6 365.1 0.2 1.7 0.2 0.0 0.0 6.3 0.3 5.8 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 1.8 0.2 0.0 0.0 0.3 5.7 0.0 0.1 0.2 1.0 0.0 0.0 0.1 1.4 0.9 0.8 0.3 0.0 0.6 0.1 0.0 0.3 REEP6 "C19orf32, DP1L1, FLJ25383, Yip2f" ENSG00000115255 "Receptor accessory protein 6" Q96HR9 19 1491166-1497927 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 217.5;liver: 398.0;testis: 283.9" "Cell type enhanced" "Detected in many" "Early spermatids: 559.1;Late spermatids: 3135.0;Proximal enterocytes: 898.7" "Cancer enhanced" "Detected in all" "liver cancer: 114.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 57.9;Hep G2: 56.2;K-562: 155.7;T-47d: 121.4" "HPA003895, HPA048015" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 45: Intestine - Brush border" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA003895: AB_1845723, HPA048015: AB_2680233" "unprognostic (1.21e-1)" "unprognostic (1.56e-1)" "unprognostic (7.76e-2)" "unprognostic (1.63e-3)" "unprognostic (3.24e-1)" "unprognostic (2.43e-2)" "unprognostic (1.92e-1)" "unprognostic (6.85e-2)" "unprognostic (7.38e-2)" "unprognostic (4.56e-1)" "unprognostic (1.49e-1)" "unprognostic (1.93e-1)" "unprognostic (1.40e-2)" "unprognostic (2.17e-1)" "unprognostic (8.08e-2)" "unprognostic (2.83e-1)" "unprognostic (5.38e-2)" 8.4 86.5 11.1 1.3 12.4 1.2 17.5 10.1 18.0 5.6 7.7 3.0 217.5 3.5 14.6 14.3 4.6 7.0 3.9 12.7 8.8 22.1 398.0 1.6 1.3 9.7 10.1 7.7 28.5 2.0 9.8 1.6 9.9 20.1 1.7 94.0 17.9 6.8 2.0 9.3 199.6 0.9 8.4 1.7 4.2 283.9 12.1 0.7 6.0 0.7 1.0 9.2 7.0 10.9 7.3 9.2 2.6 34.3 5.6 2.0 39.5 1.8 0.7 1.9 1.9 57.9 22.5 3.9 12.2 1.1 2.3 7.3 9.8 0.6 1.0 1.9 4.1 21.3 1.3 56.2 4.2 1.6 6.6 4.7 4.1 0.4 1.4 3.2 1.1 4.9 155.7 5.0 0.3 29.6 1.8 4.7 12.8 21.1 19.5 4.9 1.1 10.0 10.9 2.7 0.7 17.2 9.8 14.2 6.3 1.9 121.4 5.7 3.4 2.8 5.4 8.7 1.2 16.4 5.3 0.8 11.2 9.4 8.2 0.0 1.1 0.0 5.5 1.2 2.8 0.1 1.4 1.2 1.9 0.6 2.0 2.2 0.0 4.9 4.3 3.3 1.6 1.6 11.1 12.4 10.1 18.0 12.7 8.8 9.7 10.1 9.9 8.4 12.1 10.9 1.5 3.2 3.2 2.6 2.7 6.8 7.9 6.8 10.8 30.4 47.4 20.3 1.8 91.5 10.5 5.5 33.3 69.4 2.5 7.8 7.9 34.5 559.1 4.5 7.1 4.2 6.0 10.1 1.5 69.2 12.8 4.7 2.6 3.0 10.2 132.9 5.0 267.4 9.6 23.5 1.2 51.9 4.1 6.3 4.3 3135.0 34.2 4.1 30.2 0.0 1.7 44.2 2.1 0.0 1.5 25.0 53.6 16.6 1.9 13.1 898.7 52.0 8.3 292.8 19.7 0.8 3.3 29.9 36.5 17.5 6.7 36.0 4.3 50.1 70.7 14.7 REM1 "GES, REM" ENSG00000088320 "RRAD and GEM like GTPase 1" O75628 20 31475288-31484895 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 20.1" "Cell type enhanced" "Detected in some" "Adipocytes: 7.7;Peritubular cells: 11.7;Sertoli cells: 59.2;Smooth muscle cells: 28.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 32 "WM-115: 22.3" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 4.6" HPA049821 Approved NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "HPA049821: AB_2680898" "unprognostic (6.16e-2)" "unprognostic (3.17e-3)" "unprognostic (2.62e-1)" "unprognostic (9.65e-2)" "unprognostic (6.03e-3)" "unprognostic (1.84e-2)" "unprognostic (4.39e-1)" "unprognostic (2.15e-1)" "unprognostic (2.48e-1)" "unprognostic (3.88e-2)" "unprognostic (4.77e-3)" "unprognostic (8.03e-2)" "prognostic unfavorable (1.84e-6)" "unprognostic (7.79e-2)" "unprognostic (4.88e-2)" "unprognostic (1.57e-1)" "unprognostic (3.06e-2)" 13.9 2.2 1.2 1.7 1.1 0.0 7.5 0.9 2.1 20.1 1.3 6.5 1.3 10.5 7.2 2.0 10.0 2.2 6.2 1.0 1.0 3.2 0.8 4.6 3.0 1.0 1.1 3.9 1.1 1.1 2.7 2.1 1.1 5.5 1.0 0.0 1.6 4.9 3.3 3.2 3.7 3.2 0.9 2.5 2.4 1.4 1.3 0.7 4.8 2.4 1.5 4.8 9.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.1 0.9 2.1 1.0 1.0 1.0 1.1 1.1 0.9 1.3 1.0 7.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.4 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.5 7.1 2.3 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.2 0.0 0.0 2.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.1 0.6 5.6 0.3 3.6 1.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.8 0.0 59.2 0.6 28.1 0.0 0.2 0.1 0.9 0.0 0.1 1.5 0.0 0.0 RFPL4A "RFPL4, RNF210" ENSG00000223638 "Ret finger protein like 4A" A6NLU0 19 55759014-55763175 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 1.4;liver: 3.4;testis: 1.6" "Cell type enhanced" "Detected in some" "Early spermatids: 1.1;Langerhans cells: 1.4" "Cancer enriched" "Detected in single" 6 "testis cancer: 0.9" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 9.7" "Group enriched" "Detected in many" 4 "dendritic cells: 3.1;monocytes: 9.7" "Cell line enriched" "Detected in some" 20 "U-2 OS: 68.4" HPA046368 Uncertain Approved Centrosome,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 9: U-2 OS - Unknown function" "Cluster 41: Macrophages - Immune response" "Centrosome, Cytosol" "HPA046368: AB_2679640" "unprognostic (3.74e-1)" "unprognostic (2.96e-2)" "unprognostic (9.20e-2)" 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 3.4 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.6 0.2 1.6 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.3 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 68.4 0.0 0.2 0.4 0.4 0.2 0.0 0.0 0.0 0.0 9.7 0.0 0.0 2.2 0.0 0.0 0.0 0.0 3.1 0.0 0.1 0.0 1.4 0.0 0.7 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.0 0.1 0.3 0.0 0.0 0.0 0.0 RGS11 ENSG00000076344 "Regulator of G protein signaling 11" O94810 16 268301-275980 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.2;pituitary gland: 56.4" "Cell type enhanced" "Detected in many" "Astrocytes: 31.0;Bipolar cells: 69.7;Cone photoreceptor cells: 120.9;Excitatory neurons: 31.9;Inhibitory neurons: 33.6;Oligodendrocytes: 28.0;Rod photoreceptor cells: 67.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 2.1;ASC TERT1: 2.2;fHDF/TERT166: 2.0;HHSteC: 3.1;hTERT-RPE1: 2.4;SCLC-21H: 3.0;SH-SY5Y: 2.3;T-47d: 2.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA041692, HPA043039" Uncertain NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA041692: AB_2677619, HPA043039: AB_2678282" "unprognostic (8.39e-2)" "unprognostic (1.97e-1)" "unprognostic (5.46e-2)" "unprognostic (4.55e-3)" "unprognostic (1.46e-1)" "unprognostic (8.50e-2)" "unprognostic (7.48e-2)" "unprognostic (2.02e-1)" "unprognostic (2.93e-1)" "unprognostic (6.56e-2)" "prognostic favorable (1.24e-4)" "unprognostic (1.70e-1)" "unprognostic (1.48e-3)" "unprognostic (6.91e-3)" "unprognostic (2.27e-1)" "unprognostic (1.20e-1)" "unprognostic (1.04e-1)" 14.7 4.5 13.4 1.0 14.8 0.0 8.4 21.8 40.2 8.8 7.5 21.7 7.1 4.2 0.3 7.4 4.5 0.9 22.3 13.4 11.2 5.4 2.4 9.0 0.4 15.4 14.2 0.8 16.8 4.4 56.4 2.6 15.3 19.2 0.7 8.9 3.8 2.7 2.2 2.5 6.9 1.1 10.2 3.4 15.0 0.8 12.8 0.0 4.2 1.1 0.0 9.2 8.8 14.4 0.0 0.0 0.0 0.0 2.1 2.2 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 1.4 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.8 0.0 0.0 0.0 0.0 2.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.5 0.0 0.0 0.0 0.2 0.0 0.0 3.0 2.3 1.2 0.0 0.5 0.0 2.5 0.0 1.6 0.1 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 14.8 21.8 40.2 13.4 11.2 15.4 14.2 15.3 10.2 12.8 14.4 1.8 0.0 0.0 31.0 0.1 0.1 0.2 0.1 0.6 69.7 1.0 0.6 7.5 1.5 0.0 0.0 120.9 0.1 0.3 0.9 0.0 0.1 0.0 1.9 5.2 1.8 10.3 0.0 31.9 1.0 0.2 8.6 3.1 3.3 0.0 0.4 6.1 0.0 0.2 10.1 33.6 0.4 2.0 0.0 1.1 0.0 0.9 0.2 1.8 4.7 0.6 3.3 0.0 18.1 28.0 0.4 7.1 1.9 0.0 0.5 5.8 0.0 0.0 67.5 0.0 1.5 7.2 0.5 1.5 0.3 0.6 0.8 0.3 0.1 1.4 0.1 RHBG SLC42A2 ENSG00000132677 "Rh family B glycoprotein" Q9H310 1 156369211-156385219 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ammonia transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 9.8" "Group enriched" "Detected in some" 4 "Granulosa cells: 89.9;Theca cells: 91.3" "Group enriched" "Detected in some" 5 "liver cancer: 14.2;renal cancer: 5.1;urothelial cancer: 4.1" "Region enriched" "Detected in single" 17 "cerebellum: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CACO-2: 2.9;Hep G2: 3.0;RT4: 5.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA042726, HPA048489" Enhanced Approved Nucleoplasm NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 15: RT4 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA042726: AB_2678131, HPA048489: AB_2680417" "unprognostic (1.20e-1)" "unprognostic (2.05e-1)" "unprognostic (4.55e-3)" "unprognostic (5.04e-2)" "unprognostic (2.95e-2)" "unprognostic (3.76e-3)" "unprognostic (2.00e-1)" "unprognostic (1.19e-1)" "unprognostic (1.49e-1)" "unprognostic (2.45e-1)" "unprognostic (3.72e-1)" "unprognostic (3.63e-2)" "unprognostic (4.91e-2)" "unprognostic (1.51e-1)" "unprognostic (1.96e-1)" "unprognostic (1.91e-3)" "prognostic favorable (8.06e-4)" 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 9.8 1.9 0.0 0.0 0.1 0.0 2.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 22.0 0.0 0.0 0.0 0.0 19.6 0.3 10.3 0.3 0.0 0.1 0.0 0.0 0.2 0.6 0.1 1.3 0.0 0.1 0.0 89.9 0.0 10.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 12.4 0.3 0.1 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.1 1.3 0.2 0.0 0.0 0.0 0.8 2.3 0.4 0.0 0.4 0.0 0.0 91.3 0.0 0.1 RIPOR2 "C6orf32, DIFF48, FAM65B, KIAA0386, MYONAP" ENSG00000111913 "RHO family interacting cell polarization regulator 2" Q9Y4F9 6 24804282-25042170 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion, Chemotaxis, Differentiation, Hearing, Myogenesis" "Developmental protein, Signal transduction inhibitor" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 82.6" "Cell type enhanced" "Detected in many" "B-cells: 57.4;dendritic cells: 98.4;Respiratory ciliated cells: 83.1;Syncytiotrophoblasts: 82.8;T-cells: 38.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "neutrophil: 951.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 951.9" "Cell line enhanced" "Detected in many" "AF22: 30.9;Daudi: 73.5;fHDF/TERT166: 73.2;U-266/70: 25.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "unprognostic (4.05e-3)" "unprognostic (1.34e-3)" "unprognostic (3.55e-2)" "unprognostic (1.91e-2)" "unprognostic (1.47e-2)" "unprognostic (1.75e-2)" "unprognostic (5.89e-4)" "unprognostic (2.62e-2)" "unprognostic (1.54e-1)" "unprognostic (4.40e-3)" "unprognostic (1.64e-1)" "unprognostic (1.74e-2)" "unprognostic (8.55e-2)" "unprognostic (3.33e-2)" "unprognostic (2.30e-2)" "unprognostic (9.79e-2)" "unprognostic (1.14e-1)" 13.1 3.7 15.9 49.1 22.4 27.6 6.1 0.4 16.7 13.5 2.5 3.7 2.7 46.3 2.6 3.2 14.8 8.6 3.1 14.0 9.1 3.0 4.3 20.7 82.6 4.5 9.5 2.7 2.5 0.9 13.0 6.0 3.2 6.1 3.8 3.7 8.2 4.5 19.5 5.2 17.5 17.7 4.6 55.9 6.7 6.4 9.2 41.0 2.9 7.6 71.0 10.2 7.4 4.9 1.1 0.1 30.9 0.6 0.3 0.2 11.3 8.8 15.5 3.7 5.4 0.4 0.5 73.5 2.0 73.2 0.5 0.9 0.0 0.0 0.7 7.3 0.4 17.8 1.2 0.3 0.6 0.4 1.3 3.2 0.3 0.0 0.4 0.2 0.0 3.2 1.0 12.2 0.2 0.2 17.0 0.8 2.3 1.2 2.1 18.5 3.0 0.7 0.1 0.4 1.5 0.3 0.6 0.3 5.7 10.3 0.3 0.5 0.3 0.7 3.3 0.8 0.9 25.4 0.6 2.4 0.8 1.0 5.1 414.0 100.8 334.5 128.6 127.3 134.8 188.3 131.8 136.6 68.7 176.3 171.6 136.8 951.9 125.7 173.8 57.7 124.9 168.1 15.9 22.4 0.4 16.7 14.0 9.1 4.5 9.5 3.2 4.6 9.2 4.9 7.3 3.2 14.6 0.0 57.4 0.0 0.0 0.0 0.0 0.0 3.3 1.7 0.0 0.0 18.6 5.5 0.0 4.1 98.4 0.0 1.9 0.1 0.0 16.4 10.5 2.8 0.0 0.0 0.0 0.2 1.9 2.7 0.0 10.7 12.6 0.6 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 15.6 0.0 0.0 3.1 83.1 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 82.8 38.0 1.7 0.0 0.0 RNASE4 RAB1 ENSG00000258818 "Ribonuclease A family member 4" P34096 14 20684560-20701216 "Plasma proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 478.8" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 67.3;Gastric mucus-secreting cells: 47.4;Hepatocytes: 55.8;Intestinal goblet cells: 110.0" "Cancer enhanced" "Detected in many" "liver cancer: 6.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 92.6;ASC TERT1: 107.2;Hep G2: 136.9;HSkMC: 63.1;OE19: 92.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 61000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 27: Mucus-secreting cells - Mucin production" "unprognostic (1.07e-1)" "unprognostic (3.46e-1)" "unprognostic (5.21e-2)" "unprognostic (3.18e-4)" "unprognostic (1.20e-1)" "unprognostic (7.05e-2)" "prognostic favorable (9.62e-5)" "unprognostic (1.43e-1)" "unprognostic (2.22e-2)" "unprognostic (6.88e-2)" "unprognostic (3.71e-2)" "unprognostic (1.29e-1)" "unprognostic (3.46e-1)" "unprognostic (2.54e-2)" "unprognostic (1.57e-1)" "unprognostic (9.16e-2)" "unprognostic (4.27e-2)" 106.4 7.8 5.5 8.9 5.7 1.2 96.6 5.4 8.3 95.6 8.5 56.5 22.0 59.2 37.0 20.1 77.3 55.6 44.1 5.5 8.1 40.3 478.8 40.3 12.2 6.9 6.6 111.7 41.0 14.7 12.5 5.7 6.9 76.7 65.2 4.7 74.8 45.8 14.1 47.4 41.9 25.9 6.7 11.8 84.7 10.6 5.3 5.8 26.5 31.5 10.6 65.3 75.9 7.8 2.7 12.1 2.6 0.1 92.6 107.2 0.5 10.5 23.8 1.4 4.5 3.4 4.1 0.1 2.9 24.6 6.2 2.5 1.4 2.6 1.7 17.2 1.8 0.3 2.9 136.9 10.2 1.3 0.6 63.1 5.8 1.6 10.3 34.6 12.6 4.2 0.1 12.2 6.9 1.5 1.0 0.2 0.5 92.3 10.3 0.6 2.1 3.6 2.9 2.4 0.1 0.5 5.0 2.3 2.6 4.2 3.4 0.2 13.3 3.0 1.7 4.1 0.3 2.6 3.5 0.4 4.7 1.3 2.7 0.2 24.1 0.1 0.8 1.2 1.0 5.3 1.5 0.6 13.8 4.9 0.3 0.6 0.6 0.6 0.1 3.3 3.3 8.4 5.5 5.7 5.4 8.3 5.5 8.1 6.9 6.6 6.9 6.7 5.3 7.8 1.8 38.5 19.1 2.0 3.4 2.8 1.7 2.5 11.4 0.0 9.9 2.5 0.2 28.6 4.7 3.7 0.0 0.2 0.3 30.4 0.0 34.4 0.2 0.1 0.8 4.0 67.3 8.4 0.1 22.2 0.4 39.2 47.4 0.8 1.3 0.3 5.0 55.8 1.6 0.0 0.2 110.0 2.0 6.2 4.0 0.3 12.5 3.6 3.6 1.9 2.7 1.3 1.0 0.0 0.9 12.8 33.2 4.1 5.9 1.7 41.7 10.2 11.6 0.3 0.0 2.6 8.1 0.2 0.1 10.2 4.1 0.4 0.8 0.1 39.6 1.5 RNF128 "FLJ23516, GRAIL" ENSG00000133135 "Ring finger protein 128" Q8TEB7 X 106693794-106797016 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 62.1;liver: 124.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 67.3;Cholangiocytes: 50.1;Distal enterocytes: 49.3;Gastric mucus-secreting cells: 54.6;Hepatocytes: 76.9;Proximal enterocytes: 85.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 41.9;CAPAN-2: 35.0;Hep G2: 30.6;OE19: 96.2;RPTEC TERT1: 30.5;RT4: 88.8;WM-115: 53.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019675 Uncertain NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "HPA019675: AB_2670225" "unprognostic (1.78e-1)" "unprognostic (1.44e-2)" "unprognostic (1.23e-1)" "unprognostic (1.88e-3)" "unprognostic (1.92e-4)" "unprognostic (2.14e-3)" "unprognostic (2.37e-2)" "unprognostic (1.02e-1)" "unprognostic (2.06e-1)" "unprognostic (2.43e-2)" "unprognostic (1.55e-2)" "unprognostic (1.75e-2)" "prognostic unfavorable (1.07e-7)" "unprognostic (1.11e-2)" "unprognostic (7.61e-2)" "unprognostic (6.30e-2)" "unprognostic (5.30e-3)" 0.7 35.0 2.6 1.8 2.4 0.0 7.9 1.9 2.4 0.6 0.8 21.8 62.1 0.1 0.5 4.6 1.0 33.1 0.5 2.5 4.2 31.5 124.6 14.7 0.2 2.7 2.2 2.0 16.4 0.7 6.6 11.1 3.3 2.8 19.6 0.1 28.6 2.1 8.9 6.9 60.8 0.6 1.6 0.1 46.9 0.6 4.3 2.8 29.4 4.1 0.2 20.0 2.0 1.6 11.1 0.0 0.0 0.0 3.4 1.8 41.9 0.1 0.3 0.0 0.0 18.8 35.0 0.0 0.0 0.6 0.4 13.3 0.1 0.0 0.0 0.0 20.6 0.0 0.3 30.6 0.0 0.0 0.0 0.1 14.4 0.0 0.1 2.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 2.4 96.2 0.3 0.0 0.1 0.1 30.5 88.8 0.2 0.0 0.0 2.3 2.2 0.3 2.3 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 15.1 0.0 53.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.4 1.9 2.4 2.5 4.2 2.7 2.2 3.3 1.6 4.3 1.6 0.1 67.3 19.6 6.2 0.5 6.8 6.6 13.1 10.2 0.0 9.7 4.2 0.5 50.1 15.0 33.1 0.0 23.4 0.1 49.3 0.0 14.7 0.1 0.0 0.0 0.3 24.7 2.7 17.9 15.6 3.3 0.3 54.6 0.0 0.0 0.1 1.8 76.9 1.9 0.0 19.6 33.3 2.0 2.7 0.4 0.2 0.0 0.4 3.6 3.7 0.0 0.0 0.0 25.1 13.8 25.6 23.6 0.0 0.0 1.9 85.4 25.3 8.7 0.0 0.0 0.0 1.3 0.0 2.0 11.5 5.3 16.6 0.2 0.5 28.7 8.5 RNF150 KIAA1214 ENSG00000170153 "Ring finger protein 150" Q9ULK6 4 140859807-141212877 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 112.6;Excitatory neurons: 184.5;Inhibitory neurons: 174.3;Microglial cells: 114.3;Oligodendrocyte precursor cells: 285.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 19.7;fHDF/TERT166: 27.1;SH-SY5Y: 37.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037987 Uncertain "Intracellular and membrane" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA037987: AB_10669512" "prognostic favorable (1.41e-4)" "unprognostic (1.95e-2)" "unprognostic (8.26e-3)" "unprognostic (2.41e-2)" "unprognostic (3.31e-1)" "unprognostic (5.38e-2)" "unprognostic (2.38e-2)" "unprognostic (5.88e-2)" "unprognostic (1.09e-1)" "unprognostic (9.32e-2)" "unprognostic (3.10e-3)" "unprognostic (3.07e-1)" "unprognostic (4.02e-2)" "unprognostic (3.88e-3)" "unprognostic (9.68e-2)" "unprognostic (1.32e-3)" "unprognostic (2.41e-2)" 11.3 12.4 6.8 1.7 12.5 0.3 3.1 7.5 7.7 8.0 0.0 16.5 1.0 11.9 10.8 6.8 12.4 3.4 14.9 7.7 8.1 8.3 0.9 1.3 3.3 1.3 1.3 10.8 2.0 0.5 7.8 1.9 6.1 8.3 3.8 31.8 31.7 11.1 18.7 0.9 3.7 12.2 1.9 5.4 4.0 1.4 5.6 2.0 6.2 12.5 3.1 6.5 3.9 2.0 0.3 0.5 4.8 4.2 19.7 1.4 0.2 6.8 3.5 2.5 1.2 0.0 0.1 0.0 0.9 27.1 0.1 0.1 9.8 0.1 1.3 0.1 4.6 0.0 8.9 0.0 0.1 0.0 0.0 1.6 0.1 0.0 0.2 1.6 0.0 4.8 0.0 0.1 0.9 0.1 4.7 0.2 2.2 0.0 1.8 2.6 12.4 0.1 2.8 0.0 2.0 37.0 0.7 0.3 1.9 2.5 0.1 0.1 0.1 12.6 5.2 8.7 3.1 0.3 0.1 0.0 0.2 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 12.5 7.5 7.7 7.7 8.1 1.3 1.3 6.1 1.9 5.6 2.0 0.8 0.0 0.5 65.6 0.0 1.1 0.7 0.3 3.4 53.9 3.1 7.4 72.5 1.5 2.2 11.0 112.6 1.3 0.0 0.1 1.9 0.4 4.6 17.8 43.9 2.7 1.8 0.0 184.5 0.5 0.1 10.0 0.0 22.8 0.0 11.4 2.2 0.2 0.7 26.9 174.3 0.0 0.0 0.6 2.9 2.7 28.6 2.0 0.0 114.3 0.0 13.4 0.0 285.5 5.7 0.1 0.0 18.0 0.0 1.1 0.0 1.0 0.2 69.1 13.1 34.5 17.4 0.0 2.0 0.5 0.6 0.4 0.4 47.6 0.0 0.1 ROR1 NTRKR1 ENSG00000185483 "Receptor tyrosine kinase like orphan receptor 1" Q01973 1 63774017-64181498 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Kinase, Receptor, Transferase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 26.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 51.3;Astrocytes: 81.0;Inhibitory neurons: 69.7;Microglial cells: 36.5;Oligodendrocytes: 109.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 40.5;ASC TERT1: 50.3;CACO-2: 36.8;HHSteC: 38.3;HSkMC: 41.6;NTERA-2: 43.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Intracellular and membrane" NA NA 7700000 "Cluster 40: NK-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (5.15e-2)" "unprognostic (1.19e-2)" "unprognostic (3.65e-2)" "unprognostic (1.03e-2)" "unprognostic (6.24e-2)" "unprognostic (1.61e-1)" "unprognostic (7.11e-3)" "unprognostic (1.41e-1)" "unprognostic (4.06e-1)" "unprognostic (3.84e-1)" "unprognostic (3.20e-2)" "unprognostic (2.02e-2)" "unprognostic (3.64e-3)" "unprognostic (1.48e-2)" "unprognostic (1.52e-1)" "unprognostic (5.87e-2)" "unprognostic (5.15e-2)" 4.4 1.1 0.6 2.2 1.4 0.4 3.7 3.0 0.8 7.5 4.6 4.5 2.2 7.1 1.4 5.2 2.5 5.2 7.5 0.7 0.6 2.3 0.5 7.0 1.2 0.7 0.9 8.3 5.5 26.9 0.5 3.1 0.5 5.4 4.0 1.5 1.2 6.4 2.3 2.3 1.7 7.7 0.3 3.2 6.4 1.5 1.2 2.5 1.4 1.6 1.1 4.2 2.3 1.1 15.5 12.2 5.9 0.8 40.5 50.3 4.0 2.9 8.3 1.6 4.3 36.8 4.9 0.3 6.6 7.2 2.9 3.2 0.1 2.9 1.1 0.0 3.7 0.0 1.6 0.5 38.3 0.0 0.0 41.6 10.9 21.7 25.2 8.4 0.7 0.5 0.0 0.3 11.0 0.2 0.2 0.1 43.0 11.3 6.1 0.2 0.2 9.8 8.7 0.3 3.4 13.6 0.8 0.2 6.4 19.9 0.1 0.0 8.4 3.3 5.7 23.0 6.2 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.6 1.4 3.0 0.8 0.7 0.6 0.7 0.9 0.5 0.3 1.2 1.1 1.1 51.3 10.5 81.0 1.8 3.8 2.2 0.5 29.0 4.7 3.0 2.0 11.4 1.5 1.3 1.8 0.0 0.2 0.1 1.3 0.0 5.6 9.6 1.2 9.2 1.8 21.5 0.0 11.6 15.2 1.0 14.5 16.8 1.9 0.0 1.1 0.7 0.0 7.6 0.0 69.7 2.2 2.0 0.6 4.9 8.1 27.7 0.5 3.6 36.5 0.0 5.3 0.0 3.5 109.9 15.3 0.8 14.7 0.1 1.4 0.0 3.4 0.8 0.3 6.6 6.8 8.5 1.4 1.8 11.5 4.5 0.3 0.2 0.3 3.3 0.8 RSPO2 MGC35555 ENSG00000147655 "R-spondin 2" Q6UXX9 8 107899316-108083642 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" "Developmental protein, Heparin-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.0;intestine: 13.9;placenta: 17.3" "Group enriched" "Detected in some" 8 "Excitatory neurons: 75.3;Inhibitory neurons: 86.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.2;U-266/70: 4.2" "Group enriched" "Detected in many" 7 "amygdala: 7.9;cerebral cortex: 17.9;hippocampal formation: 21.3;white matter: 13.2" "Group enriched" "Detected in many" 4 "amygdala: 8.3;cerebral cortex: 7.7;hippocampal formation: 8.5;midbrain: 12.9;spinal cord: 7.7" "HPA024764, CAB025900, HPA053068" Uncertain "Secreted in other tissues" NA NA "Cluster 65: Brain - Ion transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB025900: , HPA024764: AB_10603236, HPA053068: AB_2682031" "unprognostic (1.10e-2)" "unprognostic (2.18e-1)" "unprognostic (3.97e-2)" "unprognostic (1.52e-1)" "unprognostic (2.04e-1)" "unprognostic (1.19e-1)" "unprognostic (8.33e-3)" "unprognostic (1.82e-1)" "unprognostic (9.48e-2)" "unprognostic (1.31e-1)" "unprognostic (1.40e-1)" "unprognostic (8.45e-2)" "unprognostic (1.95e-2)" "unprognostic (1.17e-2)" 0.2 0.0 2.8 0.7 4.4 0.1 0.0 1.3 16.2 3.4 2.6 13.9 3.4 0.0 1.7 5.9 0.0 3.2 0.2 6.6 13.2 0.0 0.4 7.1 0.0 2.6 23.0 0.3 0.0 0.0 2.9 17.3 2.0 8.7 7.8 0.3 0.0 2.3 0.0 0.0 4.6 0.3 2.1 0.0 7.6 0.7 3.5 0.0 0.0 0.0 0.0 1.7 0.8 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 4.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4.4 1.3 16.2 6.6 13.2 2.6 23.0 2.0 2.1 3.5 6.6 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 75.3 0.0 0.3 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 86.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 4.7 0.0 0.0 0.0 4.0 4.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.6 0.0 1.7 0.0 0.0 1.0 0.0 0.2 0.0 0.0 RSPO3 "FLJ14440, THSD2" ENSG00000146374 "R-spondin 3" Q9BXY4 6 127118671-127199481 "Cancer-related genes, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 51.4" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 18.5;Endothelial cells: 42.4;Fibroblasts: 73.0;Hepatic stellate cells: 26.4;Inhibitory neurons: 17.8;Leydig cells: 27.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 21.9;BJ hTERT+: 3.6;hTERT-RPE1: 6.3;U-138 MG: 4.6;U-87 MG: 4.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 21.2" HPA029957 Uncertain "Secreted to blood" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 33: Fibroblasts - ECM organization" "HPA029957: AB_10602087" "unprognostic (4.77e-2)" "unprognostic (3.95e-2)" "unprognostic (1.27e-2)" "unprognostic (2.27e-2)" "unprognostic (1.10e-1)" "unprognostic (2.99e-1)" "unprognostic (9.71e-2)" "unprognostic (1.49e-2)" "unprognostic (3.77e-2)" "unprognostic (3.21e-1)" "unprognostic (1.37e-1)" "unprognostic (3.37e-1)" "unprognostic (1.07e-3)" "unprognostic (7.94e-2)" "unprognostic (2.76e-1)" "unprognostic (1.64e-2)" "unprognostic (7.89e-3)" 30.9 15.1 2.1 16.1 2.4 0.0 12.4 3.3 4.9 13.8 0.0 7.4 2.2 51.4 28.4 5.4 25.3 11.1 0.9 8.5 1.5 4.0 6.5 5.1 3.7 1.6 1.4 3.6 1.6 0.1 3.1 35.4 0.3 6.3 6.6 0.1 5.4 20.0 39.8 2.8 10.3 48.1 0.0 1.8 13.3 1.0 1.0 2.4 3.6 5.0 1.4 8.6 7.1 0.9 0.0 21.9 0.0 0.0 1.0 0.0 0.0 0.0 3.6 0.3 0.4 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 6.3 2.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 4.6 1.8 0.6 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.4 3.3 4.9 8.5 1.5 1.6 1.4 0.3 0.0 1.0 0.9 3.6 0.0 0.0 0.7 0.1 0.9 0.1 0.0 0.6 1.5 0.2 0.9 0.5 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.4 12.3 0.3 18.5 42.4 0.0 0.0 5.9 0.0 1.1 73.0 5.1 0.3 0.0 0.0 26.4 0.4 1.6 0.0 17.8 0.0 0.0 1.0 0.8 2.2 27.4 0.4 1.8 1.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.2 6.6 2.1 3.5 0.1 0.4 0.4 0.1 1.6 0.1 0.1 0.0 0.2 RTL4 "FLJ46608, Mar4, Mart4, SIRH11, ZCCHC16" ENSG00000187823 "Retrotransposon Gag like 4" Q6ZR62 X 112454500-112457112 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "liver: 1.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "testis cancer: 1.4;thyroid cancer: 3.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003272 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 15: Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Plasma membrane, Cytosol" "HPA003272: AB_2257414" "unprognostic (9.86e-2)" "unprognostic (2.04e-4)" "unprognostic (6.35e-2)" "unprognostic (5.33e-3)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.8 1.1 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.2 0.3 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RTTN DKFZP434G145 ENSG00000176225 Rotatin Q86VV8 18 70003031-70205726 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglial cells: 69.3;Oligodendrocyte precursor cells: 48.7;Oligodendrocytes: 110.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "hTERT-HME1: 21.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041343, HPA041967, HPA075089" Uncertain Approved Centrosome,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol Centrosome "HPA041343: AB_10794409, HPA041967: AB_10796790, HPA075089: " "unprognostic (1.76e-1)" "unprognostic (2.13e-1)" "unprognostic (1.36e-1)" "unprognostic (4.11e-2)" "unprognostic (3.44e-2)" "unprognostic (6.16e-3)" "unprognostic (4.63e-3)" "unprognostic (2.36e-1)" "unprognostic (1.40e-1)" "unprognostic (4.66e-2)" "unprognostic (1.90e-1)" "unprognostic (8.25e-2)" "unprognostic (6.94e-3)" "unprognostic (1.07e-1)" "unprognostic (3.81e-1)" "unprognostic (1.32e-1)" "unprognostic (1.96e-2)" 1.4 1.2 3.5 1.6 5.0 3.1 2.1 3.6 3.4 1.5 2.1 1.3 1.1 1.8 1.5 1.1 1.6 1.2 2.8 2.6 3.0 2.3 2.7 1.6 2.2 4.5 4.0 2.7 1.8 1.7 0.8 1.6 5.1 1.1 1.5 4.1 1.3 0.6 1.8 1.3 1.3 1.0 4.2 2.0 1.3 3.3 6.0 3.6 0.9 1.1 1.9 0.9 1.1 7.1 4.4 6.6 9.4 2.7 1.8 2.0 3.9 7.5 3.4 6.8 7.0 2.5 2.5 3.8 1.0 4.7 6.0 5.4 6.9 11.0 11.1 13.1 3.0 4.1 5.9 3.1 1.3 7.7 4.0 1.6 10.9 7.2 21.2 3.1 4.2 5.8 4.3 8.4 6.1 2.0 7.4 2.1 1.8 1.0 5.8 6.0 8.6 3.9 1.1 3.2 4.0 4.3 4.6 2.6 2.8 6.2 2.8 4.4 3.4 8.8 2.3 3.1 5.7 4.1 3.8 7.8 5.1 4.9 6.0 0.2 0.2 0.1 0.2 0.0 0.4 0.6 0.4 0.3 0.0 0.2 0.6 0.3 0.1 0.3 0.0 0.2 0.3 0.1 3.5 5.0 3.6 3.4 2.6 3.0 4.5 4.0 5.1 4.2 6.0 7.1 6.1 0.0 8.6 19.6 7.1 1.5 1.7 10.1 1.8 8.2 3.9 3.9 5.0 1.5 5.7 0.0 0.0 4.0 4.9 2.9 0.0 1.1 10.6 6.0 5.2 3.4 0.0 4.2 25.4 1.6 1.9 4.0 6.1 6.0 5.1 10.9 1.8 3.7 2.3 16.8 25.8 1.5 2.0 1.3 1.4 3.2 2.1 3.3 0.0 69.3 1.3 1.9 3.1 48.7 110.8 2.0 2.4 1.9 14.7 1.1 2.2 4.1 1.7 9.7 13.1 5.1 4.0 10.6 6.7 3.5 1.7 3.0 5.8 2.5 2.6 2.3 S100P ENSG00000163993 "S100 calcium binding protein P" P25815 4 6693878-6697170 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 1410.7;stomach 1: 1742.0;urinary bladder: 1777.0" "Cell type enhanced" "Detected in many" "Club cells: 1088.3;Gastric mucus-secreting cells: 2306.9;Syncytiotrophoblasts: 2773.6;Urothelial cells: 4448.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 564.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 46 "basophil: 1789.3;eosinophil: 836.9;neutrophil: 2961.8" "Lineage enriched" "Detected in many" 73 "granulocytes: 2961.8" "Cell line enhanced" "Detected in many" "BEWO: 879.0;Hep G2: 1283.2;hTCEpi: 1185.6;OE19: 4335.4;RT4: 2619.8;SK-BR-3: 1057.4" "HPA019502, HPA075251" Enhanced Supported Nucleoplasm NA NA 1600000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA019502: AB_1856530, HPA075251: " "unprognostic (1.46e-1)" "unprognostic (1.50e-1)" "unprognostic (7.52e-2)" "unprognostic (1.44e-1)" "unprognostic (2.22e-1)" "unprognostic (7.34e-2)" "unprognostic (1.60e-3)" "unprognostic (3.92e-2)" "unprognostic (7.19e-2)" "unprognostic (9.24e-2)" "prognostic unfavorable (2.00e-4)" "unprognostic (3.87e-2)" "unprognostic (1.96e-2)" "unprognostic (1.72e-1)" "unprognostic (9.24e-2)" "unprognostic (3.65e-1)" "unprognostic (1.12e-2)" 14.0 1.7 1.0 42.4 1.4 1410.7 7.4 1.6 6.3 15.0 1.4 155.6 13.2 5.9 0.0 340.6 6.9 52.1 2.7 1.4 0.9 2.1 8.8 14.7 1.0 1.1 1.1 0.5 4.7 0.4 1.7 474.7 3.2 25.5 176.0 0.1 8.2 0.5 0.4 20.9 23.8 16.6 0.6 34.3 1742.0 1.4 1.0 10.6 0.6 12.2 96.9 1777.0 34.5 1.1 115.2 89.1 0.0 0.1 0.0 0.5 879.0 0.0 1.0 0.0 0.0 5.2 17.6 0.7 40.1 0.6 1.2 137.6 0.5 1.1 0.0 54.7 0.0 1.9 106.7 1283.2 0.0 53.4 3.2 0.6 1185.6 0.0 1.1 0.2 0.2 0.8 3.1 0.0 0.0 214.5 1.6 126.5 1.5 4335.4 149.6 0.9 0.5 0.5 0.0 2619.8 1.1 0.7 156.8 1057.4 2.4 39.9 31.0 169.6 0.5 0.0 1.4 0.2 0.9 1.2 0.7 0.8 0.1 479.1 0.2 1789.3 40.6 836.9 1.4 9.5 1.1 0.4 1.7 1.1 1.6 0.5 0.3 0.8 2961.8 0.1 5.7 0.4 1.1 16.7 1.0 1.4 1.6 6.3 1.4 0.9 1.1 1.1 3.2 0.6 1.0 1.1 0.9 9.6 48.6 0.0 6.2 1.1 318.3 568.6 4.0 0.0 3.4 3.6 1.2 27.1 1088.3 1.8 0.0 550.7 2.2 322.2 0.0 4.8 12.3 37.5 38.9 8.7 16.6 0.0 0.0 31.1 783.4 13.8 2306.9 202.5 31.6 0.0 1.4 7.4 69.2 0.0 0.0 443.7 152.5 11.8 1.0 7.4 0.0 11.0 8.8 0.0 5.6 0.0 2.1 0.0 0.1 828.1 580.9 0.0 5.9 288.4 2.2 0.5 301.5 0.0 0.0 0.1 32.1 0.5 0.6 18.6 6.3 2773.6 9.8 0.1 173.2 4448.3 S1PR5 "Edg-8, EDG8" ENSG00000180739 "Sphingosine-1-phosphate receptor 5" Q9H228 19 10512742-10517931 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.7;brain: 60.2" "Cell type enhanced" "Detected in some" "dendritic cells: 93.9;NK-cells: 164.8;Oligodendrocytes: 26.6;T-cells: 33.1" "Group enriched" "Detected in many" 5 "cervical cancer: 11.7;head and neck cancer: 8.0;lung cancer: 3.7;urothelial cancer: 6.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 299.4;MAIT T-cell: 184.9;memory CD8 T-cell: 144.9;naive CD8 T-cell: 109.3" "Lineage enriched" "Detected in many" 7 "T-cells: 299.4" "Cell line enhanced" "Detected in many" "HaCaT: 28.5;HBEC3-KT: 10.9;RT4: 18.7;T-47d: 11.6;U-2 OS: 10.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029683 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA029683: AB_10603237" "unprognostic (9.07e-3)" "unprognostic (1.27e-1)" "unprognostic (1.28e-2)" "unprognostic (5.55e-4)" "unprognostic (4.21e-1)" "unprognostic (4.85e-2)" "unprognostic (9.30e-2)" "unprognostic (1.55e-1)" "unprognostic (3.48e-2)" "unprognostic (2.29e-1)" "unprognostic (1.81e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (6.71e-7)" "unprognostic (2.46e-2)" "unprognostic (2.90e-2)" "unprognostic (1.19e-1)" "unprognostic (1.52e-1)" 0.8 0.4 21.1 0.8 35.7 19.7 0.6 32.4 44.7 5.4 8.6 0.3 0.2 0.3 4.4 12.8 0.2 0.2 0.6 19.7 23.2 0.8 1.6 3.0 1.0 39.0 34.0 0.2 1.4 0.1 0.4 1.7 35.8 2.5 0.1 0.0 2.4 0.5 0.6 18.7 0.3 0.2 26.0 11.1 0.3 0.7 30.1 0.9 0.5 0.2 2.1 2.2 10.9 60.2 1.9 2.8 0.6 0.0 0.0 0.1 0.2 0.6 0.5 0.9 0.5 0.3 0.1 0.0 7.6 0.3 1.2 28.5 1.8 10.9 2.0 0.0 1.8 0.2 2.3 0.0 0.1 0.0 0.1 0.0 5.0 3.0 0.6 0.2 0.0 0.0 0.2 0.0 0.0 3.7 1.1 0.0 4.5 0.6 0.5 0.0 2.1 0.0 0.0 18.7 0.0 0.0 4.7 0.0 0.5 1.9 11.6 3.3 0.0 1.5 10.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.5 0.5 1.2 299.4 0.2 184.9 0.6 36.3 144.9 0.6 0.5 10.8 109.3 3.9 44.5 1.1 0.8 0.6 64.2 21.1 35.7 32.4 44.7 19.7 23.2 39.0 34.0 35.8 26.0 30.1 60.2 1.0 3.2 1.9 0.0 0.6 3.6 2.2 10.9 7.4 0.0 0.1 0.9 0.9 1.5 0.9 0.0 0.0 0.1 93.9 0.0 0.0 0.0 6.2 0.1 0.2 0.6 0.0 0.8 0.1 0.2 0.3 1.7 0.5 0.0 2.5 0.0 1.8 0.3 0.2 0.0 0.1 0.0 0.0 0.8 0.3 2.3 0.0 0.6 0.0 2.8 1.2 0.0 164.8 0.0 26.6 0.2 0.0 0.0 14.7 0.2 0.0 0.1 0.4 0.0 0.0 0.1 1.9 0.0 0.2 4.8 5.1 0.1 33.1 0.0 0.0 0.4 SAMD14 FLJ36890 ENSG00000167100 "Sterile alpha motif domain containing 14" Q8IZD0 17 50110040-50130160 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.4" "Cell type enriched" "Detected in many" 4 "Bipolar cells: 56.1" "Cancer enhanced" "Detected in some" "glioma: 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 12.7;HEL: 8.6;HMC-1: 28.0;SH-SY5Y: 12.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051916 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 65: Brain - Ion transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Nucleoli fibrillar center" "HPA051916: AB_2681662" "unprognostic (2.33e-2)" "unprognostic (6.05e-2)" "unprognostic (2.85e-1)" "unprognostic (2.10e-1)" "unprognostic (3.24e-1)" "unprognostic (2.31e-1)" "unprognostic (8.84e-3)" "unprognostic (6.77e-2)" "unprognostic (1.32e-2)" "unprognostic (1.74e-1)" "unprognostic (2.61e-2)" "unprognostic (3.06e-2)" "unprognostic (1.23e-3)" "unprognostic (1.93e-2)" "unprognostic (4.00e-2)" "unprognostic (9.01e-2)" "unprognostic (7.48e-4)" 0.9 1.4 14.9 0.8 14.0 0.3 0.5 19.4 15.4 1.6 0.0 1.0 0.2 3.1 0.8 0.5 0.5 0.3 1.2 15.3 11.0 3.1 0.8 6.0 0.3 9.4 8.8 1.3 0.2 0.7 3.4 0.7 8.5 3.0 0.1 1.3 0.1 0.7 1.4 0.3 0.9 0.4 6.0 1.7 1.1 2.1 11.2 0.1 0.9 0.5 0.5 1.8 1.1 10.1 0.0 0.2 4.2 0.0 1.1 0.3 0.0 3.0 1.1 0.1 0.0 0.6 0.0 0.1 4.1 1.3 0.0 0.1 0.3 0.0 0.1 12.7 0.1 8.6 0.3 0.0 0.7 0.0 28.0 0.4 0.0 0.0 0.0 0.6 0.7 0.0 0.3 0.3 0.0 0.0 0.1 0.7 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 4.4 12.9 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.6 1.6 0.3 0.1 0.2 0.0 0.1 2.2 0.1 1.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.9 14.0 19.4 15.4 15.3 11.0 9.4 8.8 8.5 6.0 11.2 10.1 0.6 0.0 0.5 6.2 0.0 0.4 0.1 0.2 0.6 56.1 0.2 0.3 1.1 0.0 0.0 1.8 0.0 0.1 0.1 0.0 0.0 0.2 3.1 0.0 1.4 6.1 12.7 2.7 8.3 0.4 0.2 2.3 0.5 0.1 2.5 0.1 8.2 0.3 0.1 11.8 7.2 0.3 0.0 0.6 1.0 2.2 1.5 5.7 0.0 1.0 2.0 2.2 0.0 2.5 0.4 0.2 0.1 3.4 0.2 0.0 0.3 1.1 0.0 4.6 0.0 0.1 2.8 1.5 1.1 0.2 0.1 0.4 0.2 0.7 0.1 0.1 SCN4B LQT10 ENSG00000177098 "Sodium voltage-gated channel beta subunit 4" Q8IWT1 11 118133377-118152888 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Atrial fibrillation, Disease variant, FDA approved drug targets, Long QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 109.6;tongue: 56.8" "Cell type enhanced" "Detected in many" "Adipocytes: 12.3;Excitatory neurons: 18.2;Sertoli cells: 46.0;Smooth muscle cells: 38.8" "Cancer enhanced" "Detected in many" "glioma: 8.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.3;HBEC3-KT: 1.0;NTERA-2: 1.4;U-2 OS: 1.2" "Region enriched" "Detected in all" 11 "basal ganglia: 816.3" "Region enriched" "Detected in many" 4 "basal ganglia: 134.6" HPA017293 Approved NA NA "Cluster 65: Brain - Ion transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 48: Smooth muscle cells - ECM organization" "HPA017293: AB_2184174" "unprognostic (1.98e-1)" "unprognostic (1.13e-1)" "unprognostic (1.13e-1)" "unprognostic (2.43e-1)" "unprognostic (1.45e-1)" "unprognostic (1.07e-1)" "unprognostic (9.82e-3)" "unprognostic (9.17e-3)" "unprognostic (1.20e-2)" "unprognostic (1.23e-2)" "unprognostic (1.03e-2)" "unprognostic (3.27e-2)" "unprognostic (1.07e-1)" "unprognostic (2.07e-2)" "unprognostic (2.18e-3)" "unprognostic (1.53e-1)" "unprognostic (5.31e-4)" 23.5 5.4 2.6 1.2 86.6 0.0 9.2 41.3 109.6 2.1 0.0 2.6 2.4 3.1 1.6 5.3 5.4 3.2 11.8 2.1 14.0 2.1 0.4 8.9 2.1 53.3 15.4 0.5 5.1 6.8 2.7 1.8 45.9 2.2 2.1 0.9 2.5 2.3 30.4 3.9 4.7 7.1 15.2 0.0 2.9 0.7 23.1 8.6 14.5 56.8 0.7 3.0 1.4 28.5 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 86.6 41.3 109.6 2.1 14.0 53.3 15.4 45.9 15.2 23.1 28.5 12.3 0.0 0.0 2.9 0.0 1.3 0.6 2.0 2.8 1.7 0.5 5.7 4.6 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.3 0.1 3.0 0.0 0.0 18.2 0.0 0.1 3.9 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 8.2 0.0 2.0 1.2 1.4 8.7 2.1 1.1 0.0 1.9 0.0 0.5 0.0 1.5 1.4 0.0 0.0 1.5 0.0 0.1 0.0 0.1 5.8 0.8 46.0 0.6 38.8 0.1 0.6 0.5 1.1 0.0 0.1 0.0 0.0 0.2 SCN8A "CerIII, CIAT, MED, NaCh6, Nav1.6, PN4" ENSG00000196876 "Sodium voltage-gated channel alpha subunit 8" Q9UQD0 12 51590266-51812864 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 35.0" "Group enriched" "Detected in many" 8 "Excitatory neurons: 336.7;Inhibitory neurons: 280.1;Oligodendrocyte precursor cells: 104.5" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebral cortex: 35.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 13.7;ASC TERT1: 13.5;WM-115: 13.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022169, HPA043937, HPA073590" Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Vesicles, Cell Junctions" "CAB022169: , HPA043937: , HPA073590: " "unprognostic (2.96e-2)" "unprognostic (8.49e-2)" "unprognostic (6.93e-2)" "unprognostic (3.52e-6)" "unprognostic (8.13e-2)" "unprognostic (1.51e-2)" "unprognostic (1.16e-1)" "unprognostic (7.77e-2)" "unprognostic (5.44e-2)" "unprognostic (1.16e-1)" "unprognostic (4.73e-4)" "unprognostic (1.69e-2)" "unprognostic (1.29e-5)" "unprognostic (4.38e-1)" "unprognostic (1.56e-1)" "unprognostic (2.37e-1)" "unprognostic (4.75e-2)" 0.2 1.0 5.6 0.4 8.9 0.7 0.5 2.5 35.0 0.4 0.0 0.7 0.2 0.4 0.7 0.1 0.2 0.9 0.1 11.4 0.2 0.9 2.6 0.1 0.4 4.2 0.0 0.5 1.6 0.5 6.7 0.1 3.8 0.6 0.9 7.9 0.6 0.2 0.3 0.3 0.2 0.1 0.0 0.6 1.0 1.7 2.4 0.5 0.5 0.1 0.2 0.2 0.2 11.5 1.7 1.3 13.7 0.2 1.8 13.5 0.3 8.0 12.5 9.1 8.5 2.8 1.6 0.4 1.9 9.9 4.4 0.1 2.3 0.0 10.5 1.6 0.8 0.1 0.3 0.3 0.1 0.2 1.1 1.8 0.0 6.5 1.4 3.4 9.8 3.5 0.2 0.2 5.5 1.0 2.5 0.2 4.9 0.9 4.8 0.1 0.7 0.0 0.0 0.5 5.6 2.2 4.5 2.1 0.3 2.1 0.4 0.2 2.8 8.9 6.3 3.3 5.2 0.2 0.1 0.0 1.8 1.9 13.0 0.5 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.4 0.1 0.0 0.1 0.0 0.0 5.6 8.9 2.5 35.0 11.4 0.2 4.2 0.0 3.8 0.0 2.4 11.5 1.2 0.0 0.0 27.1 0.0 0.0 0.5 0.0 3.4 16.7 2.6 1.8 1.4 1.5 0.0 0.0 10.4 0.0 0.3 1.0 0.0 0.5 0.6 0.0 0.7 1.3 11.4 0.0 336.7 0.5 0.0 0.1 3.1 0.0 0.0 0.7 1.1 4.3 0.0 5.0 280.1 1.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 20.6 0.0 4.7 0.0 104.5 14.2 0.7 0.5 0.7 0.0 0.4 0.0 0.7 0.0 11.2 0.0 0.4 0.3 3.8 10.2 0.1 0.0 0.0 0.3 0.0 0.9 0.3 SDC2 "CD362, fibroglycan, HSPG, HSPG1, SYND2" ENSG00000169439 "Syndecan 2" P34741 8 96493813-96611790 "CD markers, Predicted membrane proteins" "Differentiation, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 460.8;thyroid gland: 424.5" "Cell type enhanced" "Detected in many" "Fibroblasts: 229.7;Hepatocytes: 235.5;Smooth muscle cells: 183.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 13.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 13.6" "Cell line enhanced" "Detected in many" "AF22: 643.1;EFO-21: 297.8;fHDF/TERT166: 288.4;RPTEC TERT1: 341.3;U-138 MG: 305.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025123, HPA044416" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "CAB025123: , HPA044416: AB_2678934" "unprognostic (1.25e-1)" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (3.61e-2)" "unprognostic (6.52e-3)" "unprognostic (4.18e-2)" "unprognostic (2.43e-1)" "unprognostic (2.35e-2)" "unprognostic (2.89e-2)" "unprognostic (4.56e-1)" "unprognostic (1.48e-1)" "unprognostic (6.16e-2)" "unprognostic (1.56e-2)" "unprognostic (1.45e-3)" "unprognostic (1.91e-1)" "unprognostic (2.50e-2)" "unprognostic (1.23e-1)" 109.5 36.3 35.2 35.9 41.0 10.2 66.6 37.6 49.9 157.0 26.4 77.9 21.8 76.0 15.2 50.1 84.6 44.5 68.9 32.1 51.8 88.9 460.8 56.8 18.9 41.1 46.6 170.5 61.2 30.2 61.5 124.4 37.5 63.4 40.1 29.7 25.0 104.4 19.9 25.3 39.8 90.9 38.5 25.8 41.9 25.5 49.6 5.3 424.5 58.5 8.0 84.0 58.1 33.7 0.5 0.3 643.1 0.3 230.2 214.1 0.6 94.8 113.4 54.3 60.5 19.8 0.2 0.2 297.8 288.4 8.0 0.5 114.3 1.8 47.1 0.3 44.4 0.6 56.7 250.2 7.4 1.9 2.9 83.1 2.8 123.5 3.1 210.2 1.9 0.1 64.3 0.3 23.1 6.0 0.3 16.9 68.1 0.0 0.7 0.7 101.5 2.4 341.3 57.2 19.1 49.5 0.2 0.3 4.9 217.8 27.6 73.0 51.3 305.1 91.5 1.5 53.2 6.0 0.3 1.1 96.9 0.4 97.5 0.0 2.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 13.6 0.0 0.1 0.0 0.0 0.6 35.2 41.0 37.6 49.9 32.1 51.8 41.1 46.6 37.5 38.5 49.6 33.7 11.9 57.7 38.1 93.7 1.7 53.8 78.9 29.6 15.9 36.6 41.4 30.2 32.7 37.1 5.1 57.0 12.5 1.9 0.5 0.1 29.4 14.4 31.6 29.3 65.1 10.7 3.5 10.7 4.6 15.3 2.5 229.7 9.7 76.4 1.3 44.3 17.5 235.5 109.8 5.0 22.0 1.5 138.4 20.5 154.7 18.6 52.5 62.9 62.2 21.5 68.2 17.4 0.0 7.1 1.7 8.9 1.2 104.9 2.5 41.7 0.8 56.4 4.0 12.5 32.9 100.0 183.1 5.5 57.6 1.3 39.2 3.8 4.2 33.3 5.7 17.6 SDK2 "FLJ10832, KIAA1514" ENSG00000069188 "Sidekick cell adhesion molecule 2" Q58EX2 17 73334384-73644445 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.5;cervix: 5.5;testis: 9.7" "Cell type enhanced" "Detected in many" "Early spermatids: 16.0;Enteroendocrine cells: 14.9;Excitatory neurons: 18.9;Extravillous trophoblasts: 17.1;Horizontal cells: 20.2;Inhibitory neurons: 14.8;Late spermatids: 20.0;Syncytiotrophoblasts: 17.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 13.8;BEWO: 11.4;RPMI-8226: 4.7;SuSa: 7.2;U-2 OS: 4.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014725 Approved Nucleoplasm NA NA 5300000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA014725: AB_2183303" "unprognostic (7.22e-4)" "unprognostic (5.57e-2)" "unprognostic (1.70e-1)" "unprognostic (7.00e-3)" "unprognostic (1.62e-2)" "unprognostic (3.18e-1)" "unprognostic (3.16e-1)" "unprognostic (1.15e-1)" "unprognostic (1.98e-1)" "unprognostic (1.49e-1)" "unprognostic (8.80e-4)" "unprognostic (7.69e-2)" "unprognostic (3.89e-2)" "unprognostic (1.44e-2)" "unprognostic (1.38e-1)" "unprognostic (1.37e-2)" "unprognostic (6.64e-2)" 0.1 0.5 3.9 1.1 2.9 0.6 0.6 1.2 2.8 5.5 0.0 0.6 0.1 1.6 1.3 0.6 2.4 0.6 0.9 5.4 1.9 0.3 0.1 1.1 1.1 6.5 3.2 0.3 0.1 0.9 1.4 0.3 6.5 1.8 0.3 0.9 0.6 0.7 0.2 0.5 0.8 0.2 2.0 2.7 0.5 9.7 3.7 0.7 1.3 0.3 1.0 0.4 0.7 3.7 0.0 2.0 13.8 3.9 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.0 3.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 1.8 0.0 0.0 0.5 0.0 4.7 0.0 0.0 3.1 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 4.7 0.0 0.0 4.2 1.8 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.0 3.9 2.9 1.2 2.8 5.4 1.9 6.5 3.2 6.5 2.0 3.7 3.7 0.4 0.0 2.7 6.5 4.4 0.9 4.6 9.9 2.8 6.8 0.8 5.0 2.0 1.5 1.9 0.0 0.0 6.7 0.2 0.2 0.0 0.3 16.0 0.5 3.9 0.8 14.9 0.4 18.9 0.2 17.1 4.6 0.5 1.0 1.3 5.6 0.0 0.0 0.6 20.2 14.8 0.4 0.0 0.0 0.2 20.0 0.6 0.6 1.8 2.8 1.1 9.7 0.0 6.6 6.6 0.0 0.0 0.0 1.3 2.3 0.0 0.3 0.2 0.8 0.0 1.2 0.9 10.7 3.5 0.3 0.1 17.8 0.8 10.4 0.0 1.1 SEMA3F "Sema4, SEMAK" ENSG00000001617 "Semaphorin 3F" Q13275 3 50155045-50189075 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 100.8" "Cell type enhanced" "Detected in many" "Adipocytes: 40.2;Bipolar cells: 23.4;Endothelial cells: 24.4;Hepatic stellate cells: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 108.1;HUVEC TERT2: 187.0;RT4: 112.3;SK-BR-3: 170.2;TIME: 338.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035008 Approved "Secreted to blood" NA NA 1700000 7900000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA035008: AB_10604091" "unprognostic (8.17e-2)" "unprognostic (2.01e-1)" "unprognostic (1.12e-2)" "unprognostic (1.87e-2)" "unprognostic (5.52e-3)" "unprognostic (1.71e-1)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.71e-1)" "unprognostic (9.05e-2)" "unprognostic (4.20e-1)" "unprognostic (9.55e-2)" "unprognostic (3.01e-1)" "unprognostic (2.23e-2)" "unprognostic (6.19e-2)" "unprognostic (8.56e-2)" "unprognostic (3.88e-3)" "unprognostic (6.87e-3)" 33.8 9.0 8.8 8.6 5.7 2.7 31.9 5.1 8.1 28.3 12.0 10.5 13.4 14.5 5.4 100.8 15.6 10.8 22.6 5.0 9.2 49.2 4.8 46.2 3.7 10.2 12.7 3.6 6.7 5.5 11.1 30.4 8.7 32.7 6.3 22.0 24.6 32.5 10.4 75.1 12.5 9.1 6.3 50.7 17.3 2.4 21.8 6.1 27.1 6.1 12.6 27.0 55.4 4.7 13.9 3.1 0.7 14.2 0.2 1.3 3.0 8.0 24.2 6.5 10.2 5.4 6.1 0.5 77.9 1.1 0.7 47.5 6.9 100.7 2.4 0.1 1.8 0.8 108.1 18.5 5.7 1.7 3.2 6.2 55.3 15.1 45.4 90.7 187.0 1.2 2.9 0.1 1.3 12.4 1.5 7.5 8.6 6.2 10.1 11.8 0.0 0.5 7.2 112.3 1.1 2.6 12.8 170.2 0.3 10.4 67.2 7.3 338.6 4.2 31.9 29.7 5.5 0.2 0.0 0.9 0.3 4.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 5.7 5.1 8.1 5.0 9.2 10.2 12.7 8.7 6.3 21.8 4.7 40.2 0.0 1.1 0.0 0.2 6.8 3.0 9.2 5.7 23.4 10.7 6.0 9.2 1.5 6.6 18.4 10.4 11.2 0.6 5.5 0.0 0.3 0.0 6.5 2.4 24.4 0.0 0.0 0.7 0.8 0.5 1.1 16.3 6.9 0.0 0.2 25.4 0.6 1.4 6.7 1.1 10.7 0.0 0.3 0.8 0.3 0.3 0.2 0.0 3.7 0.0 8.7 0.0 0.0 0.1 6.8 3.8 0.0 0.0 2.5 5.7 0.7 5.4 19.8 0.0 0.5 2.5 0.0 0.4 17.7 8.9 6.3 0.4 0.2 5.2 8.6 SEPHS2 "SPS2, SPS2b" ENSG00000179918 "Selenophosphate synthetase 2" Q99611 16 30443631-30445874 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 402.6" "Cell type enhanced" "Detected in many" "Distal tubular cells: 385.4;Proximal tubular cells: 384.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 477.5" "Low region specificity" "Detected in all" HPA047931 Approved Approved Nucleoplasm No No 29000 "Cluster 26: Non-specific - Mitochondria" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA047931: AB_2680216" "unprognostic (5.33e-2)" "unprognostic (2.02e-1)" "unprognostic (1.92e-2)" "unprognostic (9.85e-2)" "unprognostic (2.67e-2)" "unprognostic (6.29e-2)" "unprognostic (5.67e-2)" "unprognostic (7.69e-3)" "unprognostic (2.38e-1)" "unprognostic (9.86e-2)" "unprognostic (9.66e-3)" "unprognostic (1.49e-1)" "prognostic favorable (4.35e-8)" "unprognostic (2.24e-2)" "unprognostic (1.35e-1)" "unprognostic (3.25e-2)" "unprognostic (3.62e-2)" 27.5 30.6 16.8 33.7 17.5 26.0 33.8 18.5 19.9 24.8 21.2 75.5 136.0 19.9 23.9 20.4 20.5 34.0 27.8 18.5 20.5 158.5 402.6 28.8 44.8 18.5 18.9 14.9 35.2 48.9 20.4 25.1 19.5 28.7 65.9 19.7 33.6 23.2 41.7 21.1 105.8 25.9 18.6 29.8 62.5 11.5 20.2 43.5 37.7 32.3 41.9 27.7 14.2 19.8 77.6 68.9 23.8 83.1 71.7 45.7 62.5 52.3 64.5 50.5 62.2 42.9 57.7 110.8 79.0 56.0 45.7 42.1 44.5 47.9 51.0 71.2 137.5 110.8 35.9 204.0 90.5 62.0 477.5 58.4 100.5 47.6 87.7 31.6 47.0 80.1 91.1 69.7 45.4 114.5 93.9 127.8 59.3 58.0 51.4 90.2 41.8 85.3 62.6 68.9 50.5 43.1 44.8 129.3 179.7 47.8 113.7 204.2 39.6 52.2 37.1 50.9 32.0 59.6 103.4 57.6 45.3 114.3 59.7 8.7 19.4 30.2 14.8 16.1 22.2 17.8 20.9 21.4 21.6 20.2 25.0 17.2 17.6 31.9 20.5 15.4 22.8 14.8 16.8 17.5 18.5 19.9 18.5 20.5 18.5 18.9 19.5 18.6 20.2 19.8 76.2 44.8 40.3 3.9 34.3 37.5 1.4 47.6 58.6 0.5 66.2 52.7 49.4 1.5 39.4 64.4 0.0 1.3 41.5 108.9 385.4 112.2 0.1 34.2 25.1 32.4 35.5 20.8 6.7 82.7 1.1 30.4 68.8 59.2 31.0 20.5 0.7 9.1 1.4 0.0 8.6 31.0 63.1 2.9 34.9 0.1 0.0 42.5 44.4 5.6 37.1 0.2 1.0 5.5 4.6 57.4 42.4 0.0 30.6 1.6 11.1 384.9 27.2 1.1 0.0 2.0 49.4 0.8 0.8 45.4 42.6 1.2 35.7 52.6 46.0 0.9 SEPTIN1 "DIFF6, PNUTL3, SEPT1" ENSG00000180096 "Septin 1" Q8WYJ6 16 30378133-30395991 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 16.7;lymphoid tissue: 35.9" "Cell type enhanced" "Detected in some" "B-cells: 6.7;Cytotrophoblasts: 11.4;dendritic cells: 25.9;Fibroblasts: 4.9;Hofbauer cells: 9.2;Plasma cells: 10.2;Syncytiotrophoblasts: 4.9;T-cells: 6.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 38.2;JURKAT: 48.5;MOLT-4: 66.3;REH: 39.0;U-266/70: 21.6;U-266/84: 33.4;U-698: 23.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA041566, HPA060339, HPA073635" Enhanced Approved "Actin filaments" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "HPA041566: AB_10794671, HPA060339: , HPA073635: " "unprognostic (3.65e-3)" "prognostic favorable (9.72e-5)" "unprognostic (5.06e-2)" "prognostic favorable (3.04e-5)" "unprognostic (3.32e-4)" "prognostic favorable (6.63e-4)" "unprognostic (2.08e-1)" "prognostic favorable (7.24e-5)" "unprognostic (1.24e-2)" "unprognostic (6.52e-3)" "prognostic favorable (2.22e-4)" "unprognostic (3.46e-2)" "prognostic unfavorable (2.40e-7)" "unprognostic (1.48e-1)" "unprognostic (1.41e-1)" "unprognostic (3.95e-1)" "unprognostic (1.72e-2)" 1.6 0.9 1.0 3.6 1.1 0.7 1.1 1.2 1.9 1.9 1.0 3.4 4.1 1.4 0.7 2.0 2.0 0.3 0.8 1.0 1.1 1.4 1.9 2.6 15.3 1.0 1.0 1.6 0.8 0.5 0.7 0.3 1.1 1.7 0.0 0.1 3.2 0.8 0.2 1.3 16.7 0.7 1.0 35.9 4.4 0.2 1.4 16.0 1.9 0.6 6.6 2.0 1.6 1.0 0.3 0.0 0.1 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 38.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 7.3 3.0 0.0 0.0 0.3 0.0 5.1 1.2 0.2 0.1 0.1 0.0 0.7 0.0 48.5 0.3 16.7 0.0 0.0 66.3 1.4 0.0 0.0 0.7 39.0 0.0 2.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 21.6 33.4 23.2 0.6 7.0 0.0 118.4 2.5 102.2 319.3 2.3 245.1 170.1 286.7 292.4 9.6 179.4 264.6 268.7 8.5 230.4 1.6 270.6 329.6 272.6 1.0 1.1 1.2 1.9 1.0 1.1 1.0 1.0 1.1 1.0 1.4 1.0 1.2 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 11.4 25.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.3 4.9 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 4.9 6.1 0.0 0.0 0.0 SERPINA11 ENSG00000186910 "Serpin family A member 11" Q86U17 14 94442464-94452800 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 92 "liver: 490.6" "Cell type enriched" "Detected in some" 46 "Hepatocytes: 278.7" "Cancer enriched" "Detected in some" 9 "liver cancer: 94.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "Hep G2: 17.2" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 230000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (2.50e-2)" "unprognostic (3.26e-1)" "unprognostic (9.00e-2)" "prognostic favorable (6.30e-4)" "unprognostic (7.44e-2)" "unprognostic (2.02e-2)" "unprognostic (1.70e-1)" "unprognostic (3.44e-1)" "unprognostic (5.14e-2)" "unprognostic (1.53e-1)" "unprognostic (1.64e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.1 5.3 0.0 0.0 0.0 0.5 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 490.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 3.9 0.0 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 1.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.3 0.0 0.0 4.3 1.8 0.0 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.6 278.7 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.2 SERPINA6 CBG ENSG00000170099 "Serpin family A member 6" P08185 14 94304248-94323389 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "liver: 776.6" "Group enriched" "Detected in some" 4 "Cholangiocytes: 204.5;Hepatocytes: 390.8" "Cancer enriched" "Detected in many" 9 "liver cancer: 244.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "T-47d: 961.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA017864 Approved "Secreted to blood" NA NA 60800000000 37000000000 "Cluster 62: Liver - Hemostasis" "Cluster 6: T47d - Mammary gland" "Cluster 15: Hepatocytes - Hemostasis" "HPA017864: AB_1856721" "unprognostic (2.82e-2)" "unprognostic (1.67e-1)" "unprognostic (1.02e-3)" "prognostic favorable (6.96e-5)" "unprognostic (2.93e-3)" "unprognostic (9.98e-3)" "unprognostic (4.43e-2)" "unprognostic (3.11e-1)" "unprognostic (4.80e-3)" "unprognostic (2.94e-1)" "unprognostic (2.47e-2)" "unprognostic (4.54e-2)" "unprognostic (1.43e-1)" "unprognostic (2.14e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 1.9 0.0 3.5 0.1 0.5 0.0 0.0 12.6 35.1 0.0 0.0 0.0 43.5 776.6 0.1 0.0 0.0 0.0 0.3 17.4 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 114.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.2 0.4 0.4 4.5 0.1 0.4 0.0 0.1 0.7 0.0 0.0 961.9 0.0 0.0 0.5 0.0 0.6 0.0 0.3 0.0 0.5 1.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.1 0.1 0.1 0.7 0.0 0.0 4.4 0.0 0.4 204.5 0.3 0.0 0.0 0.3 0.0 0.4 1.9 33.1 0.0 62.6 0.3 0.4 9.0 16.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.2 9.7 390.8 0.0 0.0 0.0 0.8 2.0 8.7 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.1 1.0 1.2 0.0 0.0 0.0 0.1 43.0 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 1.8 0.1 SERPINA7 TBG ENSG00000123561 "Serpin family A member 7" P05543 X 106032435-106038727 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 612 "liver: 282.2" "Cell type enriched" "Detected in some" 27 "Hepatocytes: 182.8" "Cancer enriched" "Detected in single" 203 "liver cancer: 82.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 475 "Hep G2: 69.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA002803 Approved "Secreted to blood" NA NA 39800000000 25000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA002803: AB_1079915" "unprognostic (6.22e-2)" "unprognostic (1.63e-3)" "unprognostic (3.34e-1)" "unprognostic (2.62e-1)" "unprognostic (2.15e-3)" "unprognostic (2.95e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 282.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 182.8 0.0 0.0 0.0 0.7 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 SERPINC1 "AT3, ATIII, MGC22579" ENSG00000117601 "Serpin family C member 1" P01008 1 173903800-173917327 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1341 "liver: 5056.6" "Cell type enriched" "Detected in some" 49 "Hepatocytes: 2707.9" "Cancer enriched" "Detected in some" 871 "liver cancer: 1504.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 37 "Hep G2: 84.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001816, CAB016790, HPA024007" Supported "Secreted to blood" NA NA 120000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB016790: , HPA001816: AB_1079926, HPA024007: AB_1856732" "unprognostic (1.28e-2)" "unprognostic (2.22e-1)" "unprognostic (3.83e-2)" "unprognostic (5.98e-2)" "unprognostic (6.91e-2)" "unprognostic (1.93e-2)" "prognostic favorable (3.40e-5)" "unprognostic (1.75e-2)" "unprognostic (8.67e-2)" "unprognostic (3.48e-2)" "unprognostic (4.74e-2)" "unprognostic (1.91e-1)" "unprognostic (2.36e-2)" "unprognostic (5.28e-3)" "unprognostic (5.80e-2)" "unprognostic (6.35e-2)" "unprognostic (8.21e-2)" 0.3 0.1 0.2 0.0 0.3 0.0 0.1 0.3 0.3 0.1 0.2 0.2 0.0 0.0 0.1 0.2 0.1 0.0 0.3 0.3 0.2 3.7 5056.6 0.3 0.1 0.3 0.2 0.1 0.2 0.0 0.2 0.1 0.3 0.1 0.0 0.7 0.1 0.0 0.3 0.1 0.2 0.0 0.2 1.5 0.2 0.4 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.6 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 84.2 0.0 1.6 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.0 0.2 1.8 0.1 0.0 0.1 0.0 0.1 1.2 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.3 0.0 1.0 0.1 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.3 0.3 0.2 0.3 0.2 0.3 0.2 0.2 0.3 0.1 3.2 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 37.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.3 0.2 0.0 1.6 0.0 34.7 0.1 0.4 0.0 0.1 0.0 0.2 0.0 0.1 42.1 2707.9 0.2 0.0 0.1 0.0 0.0 55.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 4.6 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.3 3.7 0.0 0.0 0.2 SERPINE2 "GDN, nexin, PI7, PN1, PNI" ENSG00000135919 "Serpin family E member 2" P07093 2 223975045-224039318 "Plasma proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein, Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "placenta: 1091.9" "Cell type enriched" "Detected in many" 8 "Granulosa cells: 4466.0" "Cancer enriched" "Detected in all" 9 "melanoma: 271.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "naive CD4 T-cell: 12.9;naive CD8 T-cell: 6.8;NK-cell: 23.2" "Group enriched" "Detected in many" 15 "NK-cells: 23.2;T-cells: 12.9" "Cell line enhanced" "Detected in many" "BJ: 1492.9;fHDF/TERT166: 6425.1;SK-MEL-30: 2966.9;WM-115: 2183.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000277 Approved "Golgi apparatus" "Secreted in female reproductive system" NA NA 910000 "Cluster 48: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" "HPA000277: " "unprognostic (1.73e-1)" "unprognostic (7.08e-3)" "unprognostic (8.49e-2)" "unprognostic (7.78e-3)" "unprognostic (2.57e-3)" "unprognostic (5.57e-2)" "unprognostic (1.49e-2)" "unprognostic (7.43e-3)" "unprognostic (4.41e-1)" "unprognostic (7.12e-2)" "unprognostic (7.56e-3)" "unprognostic (2.40e-1)" "unprognostic (1.97e-3)" "unprognostic (1.23e-2)" "unprognostic (1.31e-1)" "unprognostic (6.18e-2)" "prognostic unfavorable (6.48e-5)" 28.0 19.8 120.3 75.7 125.9 6.5 14.3 128.6 158.7 28.1 71.1 22.7 28.2 17.4 5.6 36.2 20.8 46.0 100.0 115.9 145.9 39.3 10.8 14.5 30.9 158.1 152.6 145.6 8.5 3.4 8.7 1091.9 134.4 26.4 21.8 5.4 12.6 7.5 6.6 11.2 27.0 119.6 141.1 30.9 8.9 57.6 146.4 17.0 26.1 10.8 44.0 146.9 27.6 132.0 3.1 83.8 29.4 32.6 1172.5 438.7 4.4 1492.9 851.5 118.1 112.7 4.8 7.0 0.4 32.5 6425.1 188.0 5.0 3.5 102.5 101.0 0.6 26.8 16.6 49.9 22.7 57.7 12.8 1.5 128.3 68.5 342.0 505.6 304.6 9.0 5.4 0.5 1.9 412.1 4.5 2.3 3.9 56.2 31.8 92.3 10.3 25.2 64.5 1100.2 97.5 43.0 7.1 284.4 0.5 2966.9 385.2 1.2 6.4 1056.5 692.5 96.6 214.4 72.7 6.3 13.3 0.8 443.5 11.1 2183.6 0.0 0.0 0.0 0.7 0.0 0.5 0.8 0.6 0.6 0.0 1.2 12.9 6.8 0.5 23.2 0.0 0.2 0.7 2.7 120.3 125.9 128.6 158.7 115.9 145.9 158.1 152.6 134.4 141.1 146.4 132.0 13.5 0.0 1.1 233.1 3.1 23.3 16.0 132.2 351.7 5.3 7.9 8.5 5.3 0.0 4.6 7.3 0.0 106.1 11.3 19.5 11.7 13.0 2.6 5.3 17.7 20.9 24.0 23.1 86.1 33.2 524.3 556.7 5.6 5.9 2.5 4466.0 23.2 0.0 45.5 0.0 11.4 4.7 0.0 0.8 26.9 9.9 401.4 9.7 142.3 23.4 3.5 2.5 2.1 199.6 13.5 22.1 14.9 98.9 5.6 27.2 2.0 146.2 1.7 3.5 13.1 5.2 146.6 4.2 70.9 34.8 14.5 133.9 10.7 18.9 3.1 7.2 SERPINF1 "EPC-1, PEDF, PIG35" ENSG00000132386 "Serpin family F member 1" P36955 17 1762029-1777565 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 1875.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 697.8;Cytotrophoblasts: 795.6;Fibroblasts: 951.9;Hepatocytes: 765.0;Leydig cells: 1818.0;Peritubular cells: 1045.7" "Cancer enhanced" "Detected in all" "liver cancer: 245.2" "Region enhanced" "Detected in many" "hippocampal formation: 85.4" "Immune cell enriched" "Detected in many" 18 "plasmacytoid DC: 1454.4" "Lineage enriched" "Detected in all" 121 "dendritic cells: 1454.4" "Group enriched" "Detected in many" 4 "ASC diff: 1232.0;ASC TERT1: 956.3;Hep G2: 606.0;HHSteC: 410.6;HSkMC: 1313.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005825 Uncertain "Secreted to blood" NA NA 9290000000 44000000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA005825: AB_1079921" "unprognostic (3.85e-1)" "prognostic favorable (5.49e-4)" "unprognostic (9.44e-2)" "unprognostic (2.32e-2)" "unprognostic (2.96e-2)" "unprognostic (2.09e-1)" "unprognostic (3.32e-3)" "unprognostic (2.33e-1)" "unprognostic (7.88e-2)" "unprognostic (5.92e-2)" "unprognostic (1.69e-1)" "unprognostic (4.18e-2)" "prognostic unfavorable (1.40e-8)" "unprognostic (2.11e-3)" "unprognostic (2.82e-1)" "unprognostic (4.53e-3)" "unprognostic (1.25e-3)" 535.5 57.5 5.7 124.2 9.6 11.9 490.2 17.9 28.0 558.7 1875.2 131.3 41.9 358.2 90.2 109.3 557.4 559.7 376.5 85.4 1.1 35.1 974.8 158.9 133.5 0.1 5.1 408.3 207.6 11.2 62.4 311.6 1.3 202.8 52.0 61.4 124.6 105.8 434.8 162.9 131.7 221.7 2.8 133.2 124.7 277.7 25.4 106.2 193.1 465.5 117.7 323.4 273.5 7.0 0.5 3.7 2.8 2.0 1232.0 956.3 20.4 56.8 49.8 0.6 0.0 9.7 0.5 2.3 1.9 71.8 0.3 3.2 86.0 4.4 0.0 0.6 46.0 1.0 1.2 606.0 410.6 1.1 1.1 1313.4 6.9 0.9 1.1 11.4 0.6 4.2 117.5 0.4 63.2 0.2 7.0 7.2 30.7 0.3 1.0 2.9 219.9 1.6 0.1 6.0 1.9 42.2 0.7 0.7 57.0 3.4 6.7 184.2 2.0 0.5 17.6 14.1 1.2 0.7 2.4 28.1 1.7 0.6 0.8 0.1 12.0 1.1 0.6 4.4 0.4 9.0 0.7 0.9 79.8 5.2 2.0 5.5 1.7 1.3 0.2 1454.4 0.8 14.2 5.7 9.6 17.9 28.0 85.4 1.1 0.1 5.1 1.3 2.8 25.4 7.0 59.0 3.2 10.4 0.3 10.8 95.0 238.0 697.8 27.9 59.3 6.7 71.2 12.1 11.5 167.7 1.8 223.1 795.6 226.1 0.0 0.0 0.3 11.2 12.5 372.4 26.2 0.0 19.2 5.3 24.5 98.7 951.9 11.2 6.7 22.9 1.7 28.2 765.0 151.6 3.3 2.6 0.0 366.2 60.4 262.6 53.0 1818.0 79.0 108.5 9.4 79.0 11.6 1.0 0.5 2.0 6.8 0.1 1045.7 7.0 155.5 0.2 27.3 105.5 39.1 19.7 193.3 202.8 12.7 8.7 4.5 78.6 534.8 14.3 10.2 0.3 47.7 SERPINF2 "A2AP, AAP, ALPHA-2-PI, API, PLI" ENSG00000167711 "Serpin family F member 2" P08697 17 1742836-1755265 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "liver: 1578.5" "Cell type enriched" "Detected in many" 11 "Hepatocytes: 1007.7" "Cancer enriched" "Detected in all" 6 "liver cancer: 450.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 44.7" "Lineage enriched" "Detected in many" 23 "dendritic cells: 44.7" "Cell line enriched" "Detected in some" 24 "Hep G2: 145.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA001885, CAB024863" Approved "Secreted to blood" NA NA 11900 61000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB024863: , HPA001885: AB_1079922" "unprognostic (2.17e-3)" "unprognostic (2.56e-3)" "unprognostic (2.48e-1)" "unprognostic (7.57e-3)" "unprognostic (3.69e-2)" "unprognostic (1.45e-2)" "prognostic favorable (2.26e-5)" "unprognostic (1.44e-1)" "unprognostic (2.32e-2)" "unprognostic (1.38e-1)" "unprognostic (1.88e-3)" "unprognostic (2.18e-1)" "unprognostic (1.09e-3)" "unprognostic (7.05e-2)" "unprognostic (2.81e-1)" "unprognostic (7.68e-3)" "unprognostic (2.93e-1)" 11.6 2.0 1.4 4.3 1.5 0.4 18.3 1.2 2.2 7.1 11.1 4.2 0.7 8.7 101.4 3.0 19.6 0.7 2.5 2.0 1.4 74.1 1578.5 12.9 3.0 1.6 1.6 7.7 9.2 0.1 1.9 0.8 1.7 21.4 0.5 0.5 6.1 32.6 4.3 5.5 11.6 1.8 1.3 7.1 3.7 12.5 1.8 2.6 7.9 0.4 3.5 7.3 5.8 2.2 1.8 6.1 0.0 0.0 0.5 0.3 0.3 0.0 0.0 0.0 0.0 0.0 3.8 0.3 0.9 0.0 0.3 0.9 0.0 3.3 0.0 0.0 0.0 0.1 0.9 145.9 1.1 0.8 0.1 1.6 1.2 0.0 0.7 0.1 0.0 0.1 0.2 0.2 0.0 0.2 0.0 0.7 0.1 0.3 0.3 0.1 0.9 1.3 0.0 0.3 0.0 0.2 0.6 0.0 1.1 0.0 0.2 0.1 0.3 0.0 0.6 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 1.9 1.4 0.0 0.8 0.0 0.5 0.0 0.0 10.7 0.5 0.0 0.0 0.0 1.2 0.0 44.7 0.0 1.2 1.4 1.5 1.2 2.2 2.0 1.4 1.6 1.6 1.7 1.3 1.8 2.2 1.6 3.2 19.6 0.3 5.3 1.5 4.9 10.3 8.0 0.2 20.5 8.8 0.7 27.1 7.0 1.8 6.2 0.2 32.1 0.7 9.8 0.0 0.6 0.1 2.7 3.4 4.2 23.6 1.6 4.9 0.3 2.7 0.0 0.3 1.3 0.3 14.6 1007.7 7.7 0.0 1.9 2.1 12.2 32.2 20.1 0.8 33.8 8.2 1.8 1.0 10.9 0.1 0.0 1.0 0.7 3.8 2.7 26.7 3.2 2.8 2.2 87.5 4.4 0.4 0.0 1.3 1.2 0.4 0.5 1.3 1.6 0.3 2.6 0.0 3.3 1.8 SFXN1 "FLJ12876, SLC56A1" ENSG00000164466 "Sideroflexin 1" Q9H9B4 5 175477062-175529742 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, One-carbon metabolism, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 99.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 99.8" "Group enriched" "Detected in all" 5 "granulocytes: 99.8;T-cells: 36.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019543, HPA063745" Approved Enhanced Mitochondria NA NA 23000 "Cluster 46: Basophils - DNA binding" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 58: T-cells - T-cell receptor" Mitochondria "HPA019543: AB_1856789, HPA063745: AB_2685111" "unprognostic (4.77e-3)" "unprognostic (5.26e-2)" "unprognostic (1.54e-2)" "unprognostic (3.62e-3)" "unprognostic (2.35e-1)" "unprognostic (1.30e-2)" "unprognostic (3.59e-2)" "unprognostic (8.58e-3)" "unprognostic (2.47e-2)" "unprognostic (1.17e-2)" "unprognostic (2.48e-2)" "unprognostic (1.51e-1)" "unprognostic (1.31e-1)" "unprognostic (7.30e-2)" "unprognostic (4.98e-1)" "unprognostic (1.08e-3)" "unprognostic (4.23e-2)" 7.6 15.4 14.0 18.2 14.8 21.9 8.1 15.0 17.4 9.3 15.0 28.1 19.3 8.5 8.0 14.7 8.7 9.8 12.3 13.3 15.3 41.6 99.7 5.9 27.0 12.1 12.6 18.7 13.1 15.8 12.9 15.3 13.2 9.6 17.7 20.7 9.6 10.4 10.9 8.8 20.1 11.3 13.0 10.5 14.6 6.6 13.8 24.0 10.5 15.7 27.0 13.8 11.2 14.8 39.9 123.1 61.7 67.0 21.0 44.4 99.2 99.1 41.5 81.3 78.3 156.5 77.6 82.3 74.9 51.9 100.4 49.7 119.0 171.9 87.8 202.1 102.4 60.6 103.4 69.0 30.3 119.6 73.3 36.5 33.1 90.3 39.2 48.3 63.3 74.9 89.1 63.4 60.2 138.3 140.3 9.7 48.7 66.5 41.1 116.3 63.1 87.8 31.3 154.2 104.6 66.7 95.6 88.9 47.8 50.5 43.1 38.3 62.3 63.9 100.3 47.5 130.2 80.2 101.8 184.6 105.1 104.9 68.1 99.8 5.1 26.3 26.2 6.7 21.4 10.7 36.4 29.2 7.3 9.3 28.4 29.3 1.6 12.7 4.3 3.5 32.3 14.2 14.0 14.8 15.0 17.4 13.3 15.3 12.1 12.6 13.2 13.0 13.8 14.8 6.0 3.2 13.5 55.2 29.1 19.5 33.5 30.6 48.9 59.3 13.7 9.9 18.1 17.2 18.8 18.4 47.9 41.4 19.0 68.9 25.4 27.7 1.2 10.9 23.3 14.2 31.2 45.4 77.3 18.7 74.2 24.8 26.0 11.3 9.5 38.1 12.8 98.7 17.2 77.4 62.9 23.9 26.4 8.1 11.4 4.0 47.2 9.5 10.6 30.9 9.0 19.8 37.0 55.3 60.1 31.8 20.1 35.0 63.4 31.6 89.8 51.1 15.5 49.9 26.3 21.7 23.1 2.8 7.4 43.6 21.6 30.9 61.9 67.2 21.7 27.0 SGCA "A2, adhalin, ADL, DMDA2, LGMD2D, SCARMD1" ENSG00000108823 "Sarcoglycan alpha" Q16586 17 50164214-50175928 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 155.6;skeletal muscle: 522.4;tongue: 237.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 128.4;Early spermatids: 162.6;Late spermatids: 705.4;Skeletal myocytes: 195.2" "Cancer enhanced" "Detected in many" "prostate cancer: 4.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "intermediate monocyte: 1.4;memory B-cell: 3.3;myeloid DC: 2.2;naive B-cell: 3.3;non-classical monocyte: 1.8" "Group enriched" "Detected in many" 15 "B-cells: 3.3;dendritic cells: 2.2;monocytes: 1.8" "Cell line enriched" "Detected in some" 16 "LHCN-M2: 78.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007537 Uncertain "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA007537: AB_1079944" "unprognostic (1.34e-1)" "unprognostic (2.30e-2)" "unprognostic (1.89e-3)" "unprognostic (1.25e-1)" "unprognostic (9.87e-2)" "unprognostic (2.43e-2)" "unprognostic (9.25e-2)" "unprognostic (1.22e-2)" "unprognostic (1.15e-1)" "unprognostic (1.91e-1)" "unprognostic (7.01e-2)" "unprognostic (2.57e-1)" "unprognostic (2.07e-3)" "unprognostic (4.96e-2)" "unprognostic (2.16e-1)" "unprognostic (2.95e-1)" "unprognostic (1.15e-2)" 12.2 1.5 1.8 7.3 2.9 0.0 4.3 3.5 2.2 10.1 1.0 53.7 5.3 36.9 1.6 22.8 18.1 11.9 155.6 1.4 1.5 2.7 4.8 29.7 0.5 1.6 1.5 5.1 1.3 0.8 0.9 6.7 1.8 26.0 3.2 0.1 8.7 27.1 522.4 12.4 14.8 23.0 1.1 3.4 24.1 1.7 1.7 2.3 3.4 237.0 0.4 46.5 11.6 4.7 0.0 0.0 0.0 0.0 0.0 0.5 0.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 78.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.4 0.1 0.0 1.4 0.0 3.3 0.0 0.0 2.2 3.3 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.4 1.8 2.9 3.5 2.2 1.4 1.5 1.6 1.5 1.8 1.1 1.7 4.7 1.1 0.0 0.0 0.0 1.3 8.7 0.5 0.4 0.0 0.6 0.1 0.5 128.4 0.0 0.3 0.0 0.0 0.5 1.4 0.0 0.0 0.6 162.6 0.0 0.2 4.6 0.0 0.0 0.0 5.8 0.1 30.4 0.5 0.0 0.0 0.0 2.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 16.5 705.4 3.1 0.8 8.8 1.9 1.9 0.0 0.0 0.0 0.1 4.1 0.0 3.8 0.1 0.6 0.0 2.1 0.0 0.0 13.1 195.2 48.2 2.3 1.9 0.1 9.9 0.3 0.9 0.0 0.0 0.2 SH3PXD2A "FISH, KIAA0418, SH3MD1" ENSG00000107957 "SH3 and PX domains 2A" Q5TCZ1 10 103594027-103855543 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 86.8;BJ hTERT+: 84.8;fHDF/TERT166: 68.5;HSkMC: 64.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037922, HPA037923" Approved NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "HPA037922: AB_10697088, HPA037923: AB_10672612" "unprognostic (1.03e-1)" "unprognostic (1.04e-1)" "unprognostic (1.95e-2)" "unprognostic (3.00e-2)" "unprognostic (1.33e-1)" "unprognostic (1.52e-1)" "unprognostic (1.80e-2)" "unprognostic (1.38e-1)" "unprognostic (4.83e-1)" "prognostic unfavorable (3.18e-4)" "unprognostic (5.83e-2)" "unprognostic (3.76e-2)" "prognostic unfavorable (2.04e-6)" "unprognostic (1.25e-1)" "unprognostic (2.59e-1)" "unprognostic (5.78e-3)" "unprognostic (2.62e-2)" 18.9 8.5 49.2 11.5 45.1 1.4 14.5 25.6 38.6 49.0 2.9 27.3 5.7 31.2 7.2 30.3 25.7 17.4 16.9 32.8 32.2 7.0 23.0 17.2 4.7 38.1 40.9 29.5 8.4 1.2 14.0 16.3 39.1 18.5 13.4 17.1 14.1 13.9 19.0 29.4 14.3 26.7 44.8 13.3 13.0 3.0 42.4 6.7 9.2 14.3 5.9 21.5 31.9 64.7 1.3 5.3 13.7 16.5 48.1 86.8 7.3 39.5 84.8 13.1 12.4 0.5 0.4 0.0 7.7 68.5 1.5 13.3 0.8 35.5 11.6 2.3 14.3 16.5 21.8 19.2 31.0 8.2 4.5 64.5 27.2 20.1 43.5 9.8 8.8 17.9 6.1 9.7 16.6 0.5 0.2 8.0 5.8 11.4 2.5 6.8 5.2 1.0 5.5 4.8 10.2 5.5 3.8 0.9 19.9 7.4 0.2 5.8 15.4 11.0 7.6 14.3 17.7 10.9 24.1 0.5 10.7 11.1 42.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 49.2 45.1 25.6 38.6 32.8 32.2 38.1 40.9 39.1 44.8 42.4 64.7 22.6 6.4 45.4 10.1 7.6 91.0 26.4 45.2 56.3 46.1 9.3 13.5 22.9 22.8 37.8 3.7 27.1 12.1 3.4 48.1 0.0 5.3 3.2 7.7 109.9 23.9 37.1 10.5 59.5 0.6 32.0 42.2 12.8 11.5 17.7 21.8 23.9 87.3 13.0 89.2 96.6 74.8 22.4 7.6 34.9 7.3 105.9 7.7 33.8 15.0 19.0 1.7 2.1 5.0 117.2 6.2 27.0 80.5 7.9 32.1 4.1 1.3 21.6 35.7 39.5 32.1 55.6 1.9 3.7 37.5 38.1 4.7 6.8 15.0 22.7 61.1 SHROOM4 KIAA1202 ENSG00000158352 "Shroom family member 4" Q9ULL8 X 50591642-50814302 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.7" "Group enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 126.7;Oligodendrocytes: 463.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.7;HUVEC TERT2: 26.7;RH-30: 5.0;RPTEC TERT1: 5.5;TIME: 10.0;WM-115: 5.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA010089, HPA010565" Uncertain Approved "Nucleoplasm,Vesicles,Focal adhesion sites" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Focal adhesion sites" "Nucleoplasm, Vesicles" "HPA010089: , HPA010565: AB_1079961" "unprognostic (2.55e-2)" "unprognostic (1.43e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.34e-1)" "unprognostic (1.60e-2)" "unprognostic (4.30e-3)" "unprognostic (4.55e-2)" "unprognostic (2.13e-1)" "unprognostic (2.93e-1)" "unprognostic (1.52e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (4.66e-4)" "unprognostic (7.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.74e-2)" "unprognostic (2.75e-1)" 8.1 1.8 9.8 1.9 20.0 1.2 5.4 17.1 12.4 3.3 0.9 1.8 1.1 3.6 1.6 2.7 2.2 3.0 7.8 8.9 12.6 5.3 0.9 13.3 0.9 23.8 17.6 1.3 0.9 1.9 2.0 9.0 21.8 2.2 1.4 1.3 2.0 1.8 3.6 1.7 1.5 4.1 13.8 1.0 1.3 0.6 17.3 0.6 3.3 5.0 1.0 3.5 2.3 30.7 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.1 0.2 0.0 6.7 0.9 0.0 0.6 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.0 0.0 0.5 0.0 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 5.0 0.0 5.5 2.5 0.1 0.0 0.0 0.8 1.5 3.6 0.1 0.1 10.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 1.3 0.2 5.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 20.0 17.1 12.4 8.9 12.6 23.8 17.6 21.8 13.8 17.3 30.7 45.0 25.6 18.6 3.3 0.0 3.6 2.0 1.9 2.2 0.3 1.0 1.5 4.2 0.0 2.0 5.5 0.0 0.6 0.2 1.1 3.9 0.7 0.1 2.8 5.4 46.5 3.0 0.0 1.1 0.2 3.0 3.0 0.0 2.9 3.8 2.3 30.7 0.9 0.5 0.0 1.1 2.8 0.0 2.4 2.7 0.6 1.2 0.6 0.0 51.5 0.0 3.6 0.0 126.7 463.4 2.3 1.0 1.2 0.0 1.2 0.3 3.5 2.5 0.6 0.0 2.5 2.6 0.0 1.0 2.0 3.1 0.3 0.6 3.0 3.2 1.6 SIGLEC1 "CD169, dJ1009E24.1, FLJ00051, FLJ00055, FLJ00073, FLJ32150, sialoadhesin, SIGLEC-1, SN" ENSG00000088827 "Sialic acid binding Ig like lectin 1" Q9BZZ2 20 3686970-3712600 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Endocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 11 "Hofbauer cells: 78.6;Kupffer cells: 93.4;Macrophages: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.5" "Lineage enhanced" "Detected in single" "monocytes: 1.5" "Cell line enriched" "Detected in single" 19 "THP-1: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA053457 Supported "Intracellular and membrane" NA NA 260000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA053457: AB_2682158" "unprognostic (2.05e-1)" "unprognostic (9.27e-3)" "unprognostic (3.83e-4)" "unprognostic (4.87e-3)" "unprognostic (3.40e-2)" "unprognostic (1.06e-1)" "unprognostic (2.15e-1)" "unprognostic (6.98e-2)" "unprognostic (2.27e-2)" "unprognostic (1.68e-1)" "unprognostic (1.40e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (8.69e-5)" "unprognostic (8.71e-2)" "prognostic unfavorable (4.36e-4)" "unprognostic (1.11e-2)" "unprognostic (9.31e-2)" 23.0 13.7 2.0 7.7 2.9 12.3 8.6 1.9 6.5 1.8 7.5 10.2 5.1 2.0 1.8 2.2 7.0 8.5 6.4 1.8 2.2 3.9 8.4 16.7 12.7 10.2 3.3 2.7 1.6 0.5 2.3 18.8 10.9 1.9 6.6 0.3 5.4 1.2 3.7 3.0 11.2 7.7 5.0 18.9 5.1 2.5 10.9 3.6 3.7 2.6 1.9 7.6 3.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 2.0 2.9 1.9 6.5 1.8 2.2 10.2 3.3 10.9 5.0 10.9 3.9 0.5 3.2 4.4 0.0 0.1 0.4 0.0 0.0 0.0 0.4 0.0 0.3 2.4 0.0 0.6 0.0 2.1 0.9 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.2 0.2 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 78.6 0.0 0.3 0.0 0.0 93.4 6.3 0.1 0.0 42.6 0.0 3.7 2.1 0.2 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 1.4 1.0 0.0 0.1 0.6 0.6 1.9 0.4 0.0 0.0 0.0 SIRT5 ENSG00000124523 "Sirtuin 5" Q9NXA8 6 13574227-13615158 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 52.5;Distal tubular cells: 52.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021798, HPA022002, HPA022992" Approved Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 38: EFO-21 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA021798: AB_1856911, HPA022002: AB_1856913, HPA022992: AB_1856915" "unprognostic (8.53e-2)" "unprognostic (7.79e-2)" "unprognostic (4.71e-2)" "unprognostic (5.26e-3)" "unprognostic (6.19e-2)" "unprognostic (1.63e-1)" "unprognostic (8.72e-2)" "unprognostic (1.38e-1)" "unprognostic (8.54e-3)" "unprognostic (2.77e-3)" "unprognostic (1.02e-1)" "unprognostic (1.65e-1)" "prognostic favorable (8.76e-10)" "unprognostic (2.39e-1)" "unprognostic (6.88e-2)" "unprognostic (6.86e-2)" "unprognostic (2.36e-3)" 7.2 6.0 9.4 5.2 10.6 5.8 6.6 10.4 12.2 5.4 13.5 8.1 7.7 6.1 5.6 5.6 9.2 5.2 28.6 10.5 10.6 11.5 33.5 5.4 8.3 9.2 9.6 10.1 6.7 16.2 7.3 5.6 9.9 6.4 8.7 6.1 10.6 6.8 33.4 7.9 9.8 5.9 8.4 9.6 8.2 6.8 10.9 8.2 9.0 38.0 7.2 6.0 5.4 11.1 10.5 8.9 8.1 10.4 5.7 8.9 7.6 5.1 5.3 6.1 8.0 12.9 11.1 14.1 35.7 4.3 10.9 16.9 7.4 11.1 7.6 5.9 10.3 8.5 5.6 20.5 11.0 6.7 6.7 7.8 19.9 4.5 19.9 12.7 10.3 20.3 13.8 4.6 6.5 12.3 8.2 13.2 7.7 16.9 13.7 15.4 4.4 24.4 10.3 11.0 13.7 4.5 4.3 7.9 25.9 25.0 11.6 4.9 8.6 6.6 3.4 4.2 5.8 11.6 15.4 10.7 4.5 7.3 8.4 0.7 6.0 16.7 9.9 9.2 10.7 14.0 13.0 9.5 6.3 12.7 11.8 10.8 2.6 11.8 17.3 5.9 10.7 7.9 9.4 10.6 10.4 12.2 10.5 10.6 9.2 9.6 9.9 8.4 10.9 11.1 16.6 28.9 3.2 30.0 8.2 4.1 11.4 14.9 10.8 7.3 9.7 9.9 52.5 15.7 16.8 11.0 0.0 20.5 6.6 9.4 52.8 13.0 2.9 13.1 5.4 12.3 6.1 15.8 36.6 6.7 10.5 6.7 6.6 8.1 0.0 23.5 9.7 25.7 9.4 1.7 39.2 13.2 8.2 13.9 3.8 2.0 8.1 8.4 5.4 14.0 6.3 11.6 10.3 15.1 25.8 7.2 13.4 5.7 4.7 6.2 18.1 34.1 22.5 7.2 0.0 9.8 6.6 8.5 12.0 9.8 4.5 10.7 7.9 13.2 15.0 9.0 SKAP1 "SCAP1, SKAP55" ENSG00000141293 "Src kinase associated phosphoprotein 1" Q86WV1 17 48133442-48430275 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 35.8" "Cell type enhanced" "Detected in many" "dendritic cells: 107.1;granulocytes: 120.1;Late spermatids: 156.1;NK-cells: 213.1;T-cells: 147.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CAPAN-2: 29.3;HDLM-2: 16.0;HMC-1: 13.0;JURKAT: 22.2;Karpas-707: 15.7;RPMI-8226: 19.8;RPTEC TERT1: 22.6;U-266/70: 14.8;U-266/84: 11.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA002969, CAB025882, CAB055513" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Plasma membrane" Cytosol "CAB025882: , CAB055513: , HPA002969: AB_1079870" "prognostic favorable (5.07e-4)" "unprognostic (1.10e-2)" "unprognostic (2.19e-2)" "unprognostic (1.80e-2)" "unprognostic (2.28e-2)" "unprognostic (1.43e-2)" "unprognostic (2.61e-2)" "unprognostic (1.57e-2)" "unprognostic (8.39e-2)" "unprognostic (1.81e-1)" "unprognostic (3.38e-1)" "unprognostic (1.71e-1)" "unprognostic (5.71e-2)" "unprognostic (6.20e-2)" "unprognostic (2.72e-1)" "unprognostic (1.94e-1)" "prognostic favorable (3.14e-4)" 1.4 6.4 0.1 11.2 0.2 6.5 8.3 0.0 0.2 10.1 0.0 3.4 2.7 3.8 17.2 1.7 13.7 3.6 0.5 0.3 0.5 11.9 3.1 5.4 28.7 0.9 0.2 0.8 5.4 13.8 9.8 0.5 0.4 1.0 4.6 0.0 6.1 6.2 0.2 0.8 5.3 1.1 1.4 12.2 4.9 9.5 0.2 35.8 1.0 0.5 26.6 6.2 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 29.3 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 16.0 0.3 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 0.0 0.0 0.1 22.2 0.0 15.7 0.2 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 19.8 22.6 0.0 0.0 0.0 1.7 0.0 0.2 0.0 7.8 0.0 0.1 0.0 0.1 0.0 0.0 14.8 11.2 0.0 0.0 0.0 0.0 12.6 0.7 1.8 171.0 0.5 144.2 15.9 139.7 155.6 0.7 54.5 121.2 135.4 3.7 121.0 1.1 0.9 268.9 126.8 0.1 0.2 0.0 0.2 0.3 0.5 0.9 0.2 0.4 1.4 0.2 0.3 3.1 3.2 10.5 1.0 27.1 2.0 0.1 0.0 2.8 0.1 9.7 5.3 0.8 0.0 3.1 9.2 0.0 0.1 107.1 0.5 46.9 0.5 58.1 12.3 1.6 2.4 1.2 9.0 7.0 2.0 0.1 1.1 7.7 14.0 120.1 0.0 7.5 28.7 0.3 0.0 1.4 1.1 0.0 5.4 3.1 156.1 1.5 3.8 1.8 12.2 2.6 1.6 213.1 0.5 1.6 1.3 0.3 0.7 31.0 0.2 0.8 2.0 1.5 0.3 6.6 0.7 1.1 46.4 9.9 0.7 1.3 0.3 147.0 1.2 0.3 0.6 SLC10A5 ENSG00000253598 "Solute carrier family 10 member 5" Q5PT55 8 81693631-81695058 "Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 3.9;liver: 11.3" "Cell type enhanced" "Detected in some" "Distal enterocytes: 4.1;Enteroendocrine cells: 3.6;Gastric mucus-secreting cells: 6.1;Hepatocytes: 2.8;Proximal enterocytes: 7.2;Respiratory ciliated cells: 4.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 3.6" "Not detected" "Not detected" HPA025966 Uncertain Approved "Plasma membrane" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA025966: AB_1856959" "unprognostic (6.42e-2)" "unprognostic (3.89e-1)" "unprognostic (1.25e-2)" "unprognostic (2.34e-2)" "unprognostic (8.13e-3)" "unprognostic (1.91e-1)" "unprognostic (5.71e-2)" "unprognostic (5.63e-2)" "unprognostic (3.67e-1)" "unprognostic (2.41e-1)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" "unprognostic (8.95e-2)" "unprognostic (2.51e-1)" "unprognostic (2.24e-1)" "unprognostic (1.67e-1)" "unprognostic (2.82e-7)" 0.1 0.2 0.9 0.3 0.9 0.0 0.2 1.8 1.4 0.3 0.0 2.8 3.2 0.3 0.7 0.3 0.3 1.7 0.2 0.8 0.9 1.8 11.3 0.2 0.0 0.6 0.7 0.3 1.0 0.2 1.0 0.0 0.7 0.6 3.7 0.5 0.3 0.2 0.2 0.4 3.9 0.2 0.2 0.3 3.4 0.1 1.0 0.1 0.5 0.3 0.2 0.3 0.2 0.8 0.2 0.2 0.2 0.3 0.2 0.5 0.2 0.2 0.1 0.2 0.1 0.2 0.1 0.4 0.5 0.0 0.0 0.2 0.3 0.1 0.2 0.2 0.8 0.6 1.3 0.5 0.1 0.0 0.1 0.1 0.6 0.2 0.8 0.6 0.1 0.2 0.5 0.3 0.3 0.2 0.2 0.4 0.0 3.6 0.2 0.0 0.1 0.2 0.2 1.4 0.5 0.3 0.1 0.2 0.1 0.1 0.5 0.1 0.3 0.3 0.5 0.4 0.5 0.3 0.9 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 1.8 1.4 0.8 0.9 0.6 0.7 0.7 0.2 1.0 0.8 0.2 0.0 0.0 0.3 0.1 0.0 0.1 0.2 0.0 0.3 0.3 0.3 0.6 0.0 0.5 0.0 0.0 0.0 0.0 4.1 1.9 0.4 0.0 0.4 0.3 0.2 3.6 0.0 0.9 1.1 0.1 0.1 6.1 0.3 0.0 0.3 0.7 2.8 0.0 0.0 0.8 1.5 2.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.5 1.9 0.0 0.0 0.4 7.2 1.7 4.1 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.5 2.4 0.5 SLC13A2 NaDC-1 ENSG00000007216 "Solute carrier family 13 member 2" Q13183 17 28473293-28497781 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 119.6;kidney: 38.2;salivary gland: 44.9" "Group enriched" "Detected in some" 6 "Proximal enterocytes: 290.2;Proximal tubular cells: 97.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA014963 Enhanced NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA014963: AB_1857096" "unprognostic (8.47e-2)" "unprognostic (7.63e-3)" "unprognostic (4.36e-3)" "unprognostic (2.06e-1)" "unprognostic (2.36e-3)" "unprognostic (3.06e-1)" "unprognostic (2.28e-4)" "unprognostic (1.50e-1)" "unprognostic (1.74e-1)" "unprognostic (1.00e-2)" "prognostic favorable (9.00e-4)" "unprognostic (2.16e-1)" "unprognostic (2.64e-1)" "unprognostic (1.50e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.7 6.1 119.6 0.0 3.0 0.0 0.0 6.8 0.0 0.0 0.0 38.2 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.8 0.8 44.9 11.4 0.0 3.1 90.8 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.8 0.0 0.0 13.7 10.9 0.6 27.1 1.6 3.7 12.5 0.0 0.7 29.3 9.8 0.7 0.0 0.0 0.0 0.2 4.8 0.0 0.1 7.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 31.4 0.0 0.0 0.4 0.0 0.0 0.7 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.2 15.7 0.0 0.0 0.0 290.2 97.8 0.3 0.4 0.0 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.5 0.0 25.8 0.5 SLC16A4 "MCT4, MCT5" ENSG00000168679 "Solute carrier family 16 member 4" O15374 1 110362851-110391082 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 124.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 71.7;Proximal tubular cells: 192.3" "Cancer enhanced" "Detected in all" "renal cancer: 35.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.5" "Lineage enriched" "Detected in single" 4 "B-cells: 1.5" "Cell line enhanced" "Detected in many" "BEWO: 20.4;BJ hTERT+: 20.7;CAPAN-2: 30.8;HHSteC: 19.2;hTERT-RPE1: 42.6;SK-MEL-30: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046986, HPA060163" Approved Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 43: B-cells - Humoral immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Microtubules, Cytosol" "Cytokinetic bridge" "HPA046986: AB_2679892, HPA060163: " "unprognostic (2.04e-1)" "unprognostic (1.69e-1)" "unprognostic (2.56e-1)" "unprognostic (2.77e-3)" "unprognostic (1.53e-1)" "unprognostic (2.22e-1)" "unprognostic (2.00e-2)" "unprognostic (7.94e-2)" "unprognostic (2.29e-1)" "unprognostic (1.81e-1)" "unprognostic (1.70e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.69e-4)" "unprognostic (3.68e-2)" "unprognostic (9.16e-2)" "unprognostic (1.71e-2)" "unprognostic (9.46e-2)" 4.9 2.9 2.7 4.6 3.1 1.0 6.9 5.8 4.4 4.2 15.4 3.6 9.5 3.0 22.4 2.7 4.0 13.7 4.6 3.5 4.1 124.1 16.3 9.2 3.4 4.1 3.1 21.4 0.9 0.4 3.8 28.6 3.9 3.8 1.6 2.3 3.6 5.8 1.3 1.3 11.4 3.4 4.1 2.7 2.7 5.2 3.0 0.6 8.5 3.9 1.1 7.9 3.5 4.2 0.4 9.8 2.3 2.7 6.3 12.9 20.4 5.3 20.7 1.8 5.3 3.1 30.8 0.6 5.7 17.1 0.1 0.5 0.1 1.9 1.9 0.5 2.5 0.5 2.7 3.3 19.2 0.9 0.5 10.0 0.3 3.0 0.2 42.6 4.1 0.8 0.5 1.2 3.3 1.0 0.4 0.6 0.9 0.0 0.3 0.2 1.3 0.1 3.7 0.4 1.2 0.9 0.6 9.8 30.6 9.0 0.7 0.1 0.4 1.4 0.7 0.3 1.5 0.5 0.1 1.6 1.1 0.4 6.1 0.0 0.2 0.1 0.1 0.0 0.0 1.5 0.1 0.0 0.0 0.3 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.1 2.7 3.1 5.8 4.4 3.5 4.1 4.1 3.1 3.9 4.1 3.0 4.2 1.9 12.8 20.8 2.3 5.8 3.1 6.1 11.2 1.2 11.5 14.7 6.5 1.1 11.5 6.8 71.7 6.2 39.5 5.8 0.9 3.9 2.7 0.5 3.3 6.8 4.6 3.5 2.7 8.2 0.9 34.6 18.2 1.5 3.3 5.1 5.2 4.2 5.0 4.2 3.3 7.1 0.9 4.1 1.6 3.0 2.2 18.0 1.8 10.6 15.0 1.8 2.4 9.2 2.5 4.7 1.9 1.2 11.7 1.2 3.1 38.4 192.3 3.5 20.1 0.0 4.5 5.4 3.4 1.9 0.5 3.7 35.2 3.9 7.0 1.4 7.2 SLC17A8 "DFNA25, VGLUT3" ENSG00000179520 "Solute carrier family 17 member 8" Q8NDX2 12 100357074-100422055 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hearing, Ion transport, Neurotransmitter transport, Sodium transport, Symport, Transport" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 11.3;intestine: 5.2" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 13.3;Proximal enterocytes: 43.1" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Group enriched" "Detected in many" 5 "basal ganglia: 11.3;midbrain: 8.3;pons: 6.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" CAB079058 Supported NA NA "Cluster 45: Intestine - Brush border" "Cluster 45: Enterocytes - Digestion" "CAB079058: " "unprognostic (4.52e-3)" "unprognostic (2.18e-1)" "unprognostic (8.56e-2)" "unprognostic (1.32e-3)" "unprognostic (3.65e-1)" "unprognostic (7.67e-2)" "unprognostic (1.25e-1)" "unprognostic (1.71e-2)" "unprognostic (8.89e-2)" "unprognostic (3.55e-1)" 0.0 0.0 0.4 0.0 11.3 0.0 0.0 0.0 1.6 0.0 0.7 0.4 0.7 0.1 0.0 0.0 0.3 0.0 0.0 0.4 1.3 0.0 0.5 0.0 0.0 0.4 8.3 0.0 0.0 0.0 0.0 0.3 6.5 0.0 0.3 1.2 0.0 0.0 0.0 0.0 5.2 0.0 0.2 0.0 0.0 0.1 1.6 1.4 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 11.3 0.0 1.6 0.4 1.3 0.4 8.3 6.5 0.2 1.6 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 13.3 0.1 0.1 0.0 0.0 0.4 0.0 3.9 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 6.6 1.1 0.0 3.2 0.0 0.0 0.3 0.0 0.0 1.0 0.0 0.0 0.0 1.5 0.2 0.0 1.7 0.0 0.0 0.0 43.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 SLC22A10 "hOAT5, OAT5" ENSG00000184999 "Solute carrier family 22 member 10" Q63ZE4 11 63137867-63369718 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 160 "liver: 100.8" "Group enriched" "Detected in some" 10 "Excitatory neurons: 6.4;Hepatocytes: 21.0" "Cancer enriched" "Detected in single" 14 "liver cancer: 6.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.17e-2)" "unprognostic (9.77e-2)" "unprognostic (7.07e-3)" "unprognostic (7.46e-4)" "unprognostic (7.62e-3)" "unprognostic (2.87e-1)" "unprognostic (1.56e-1)" "unprognostic (6.52e-2)" "unprognostic (4.25e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 100.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 6.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 21.0 0.0 0.0 0.7 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 SLC24A3 ENSG00000185052 "Solute carrier family 24 member 3" Q9HC58 20 19212642-19722926 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Potassium transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 81.7" "Group enriched" "Detected in many" 9 "Astrocytes: 134.5;Inhibitory neurons: 327.0;Oligodendrocyte precursor cells: 375.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39 "basophil: 5.8;eosinophil: 1.8" "Lineage enriched" "Detected in single" 58 "granulocytes: 5.8" "Cell line enriched" "Detected in some" 4 "HMC-1: 75.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043400, HPA045497" Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Cytosol "HPA043400: AB_2678462, HPA045497: AB_2679349" "unprognostic (8.74e-2)" "unprognostic (1.13e-2)" "unprognostic (1.16e-1)" "unprognostic (1.41e-1)" "unprognostic (7.40e-2)" "unprognostic (2.09e-1)" "unprognostic (2.40e-1)" "unprognostic (7.62e-2)" "unprognostic (3.04e-2)" "unprognostic (3.25e-2)" "unprognostic (1.05e-1)" "unprognostic (5.40e-2)" "unprognostic (1.21e-3)" "unprognostic (3.85e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (6.08e-4)" "unprognostic (7.36e-3)" 10.4 3.1 16.2 4.0 11.7 1.4 4.9 13.3 56.1 17.8 2.7 10.8 3.8 28.3 24.3 20.6 20.0 13.0 1.1 81.7 18.6 1.1 0.7 5.5 1.0 13.6 19.2 14.6 0.7 7.5 1.2 3.0 9.1 10.9 5.4 7.3 4.7 17.5 40.9 7.0 5.0 29.1 10.3 2.4 3.8 1.5 34.8 1.9 3.0 16.9 2.7 8.6 8.9 5.4 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.8 13.3 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.4 0.0 0.0 18.2 0.0 0.0 0.7 0.0 75.7 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 8.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 9.0 0.0 0.6 17.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.8 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.2 11.7 13.3 56.1 81.7 18.6 13.6 19.2 9.1 10.3 34.8 5.4 0.2 3.2 1.1 134.5 0.1 1.1 1.1 0.4 0.0 19.1 5.0 2.3 0.4 0.0 1.3 1.8 0.0 8.5 0.1 0.3 0.0 0.1 17.0 1.2 29.8 0.4 7.7 3.4 11.8 0.0 0.3 1.9 0.0 1.6 26.6 0.1 0.4 0.0 0.6 1.7 327.0 4.1 0.0 0.0 0.7 18.3 3.7 1.1 0.0 12.2 0.0 3.1 0.0 375.5 2.4 0.2 2.8 4.1 0.4 0.8 0.4 0.0 0.0 2.2 0.0 2.7 3.0 0.5 0.8 2.9 4.1 3.4 0.4 0.1 0.7 3.8 SLC25A13 "ARALAR2, CITRIN, CTLN2" ENSG00000004864 "Solute carrier family 25 member 13" Q9UJS0 7 96120220-96322147 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 150.1" "Cell type enhanced" "Detected in all" "Hepatocytes: 153.4;Oligodendrocytes: 439.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018997 Enhanced Supported Mitochondria NA NA 21000 "Cluster 14: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA018997: AB_1857023" "unprognostic (3.61e-2)" "unprognostic (7.99e-2)" "unprognostic (6.99e-2)" "unprognostic (7.19e-2)" "unprognostic (1.14e-1)" "unprognostic (3.44e-2)" "unprognostic (1.42e-2)" "unprognostic (6.67e-2)" "unprognostic (2.31e-2)" "unprognostic (5.46e-2)" "unprognostic (1.01e-1)" "unprognostic (6.99e-2)" "prognostic favorable (9.14e-4)" "unprognostic (1.15e-1)" "unprognostic (1.05e-1)" "unprognostic (3.32e-1)" "unprognostic (7.09e-2)" 9.2 14.3 7.0 8.9 13.7 8.0 10.3 13.7 10.0 8.0 15.1 16.3 16.0 7.6 10.2 9.6 9.5 9.9 6.6 6.7 9.9 32.3 150.1 7.9 7.1 13.6 12.2 7.8 9.6 13.8 8.3 16.1 13.0 8.2 17.8 19.4 7.7 12.5 7.0 12.3 13.4 6.7 10.1 10.0 14.4 7.4 11.3 3.9 13.7 3.3 8.7 11.0 7.6 20.2 45.3 39.2 44.2 15.5 7.5 6.0 61.8 11.2 8.5 26.5 26.7 70.7 41.2 20.2 51.9 7.2 57.8 26.3 50.1 16.2 31.0 8.0 33.0 23.0 34.4 55.4 17.4 29.5 17.4 15.8 16.9 22.7 20.4 10.1 31.0 3.0 65.9 7.6 13.0 49.6 0.1 27.6 78.0 47.8 24.0 11.6 26.3 46.8 63.7 42.1 21.1 69.0 38.8 81.1 67.3 72.9 24.2 22.4 18.2 19.6 43.6 46.8 34.5 15.2 40.8 12.7 24.1 28.0 32.9 0.4 3.1 2.2 1.4 4.5 1.5 2.4 1.1 1.3 6.1 1.2 0.7 0.9 0.6 2.0 5.1 3.1 1.2 1.4 7.0 13.7 13.7 10.0 6.7 9.9 13.6 12.2 13.0 10.1 11.3 20.2 31.5 9.6 12.6 60.7 19.7 7.4 8.5 8.6 16.5 36.5 13.6 17.1 8.3 27.1 9.2 18.4 54.2 29.2 8.9 32.1 27.4 19.8 11.0 44.0 23.2 20.7 37.8 15.3 26.6 19.1 26.5 18.8 44.4 34.2 14.5 30.4 11.7 153.4 23.2 10.1 43.7 22.3 12.2 23.8 10.0 11.1 13.1 21.5 21.4 82.4 13.2 17.6 8.2 53.3 439.6 22.6 23.7 15.8 12.7 14.9 27.1 74.9 14.2 47.3 13.1 19.0 16.9 7.0 14.5 25.4 8.0 20.0 7.9 21.6 25.5 15.4 SLC27A2 "ACSVL1, FACVL1, FATP2, hFACVL1, HsT17226, VLACS, VLCS" ENSG00000140284 "Solute carrier family 27 member 2" O14975 15 50182196-50236385 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 157.7;liver: 288.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 265.5;Hepatocytes: 205.7;Proximal enterocytes: 81.0;Proximal tubular cells: 198.9;Respiratory ciliated cells: 70.2" "Cancer enhanced" "Detected in many" "liver cancer: 49.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 30 "basophil: 63.5" "Lineage enriched" "Detected in many" 30 "granulocytes: 63.5" "Cell line enhanced" "Detected in many" "A549: 50.0;HaCaT: 89.3;HL-60: 66.3;OE19: 101.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026089 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA026089: AB_1857060" "unprognostic (3.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (2.10e-2)" "unprognostic (3.06e-1)" "unprognostic (1.10e-1)" "unprognostic (4.06e-3)" "unprognostic (3.33e-1)" "unprognostic (1.89e-1)" "unprognostic (6.38e-3)" "unprognostic (4.83e-2)" "unprognostic (1.82e-1)" "prognostic favorable (7.48e-6)" "unprognostic (5.01e-3)" "unprognostic (4.08e-1)" "unprognostic (1.22e-2)" "prognostic favorable (6.40e-4)" 4.8 16.0 1.7 2.9 2.0 6.5 13.3 1.7 3.2 1.6 9.2 18.2 11.1 0.3 65.9 2.6 10.9 2.3 0.0 2.7 2.4 157.7 288.0 1.7 1.5 0.8 1.1 0.1 7.2 4.1 12.4 17.3 0.8 5.4 16.2 3.4 0.9 1.0 0.0 1.2 21.3 0.8 0.8 0.4 1.8 0.9 2.5 0.5 4.6 0.0 1.7 3.6 1.2 0.7 0.0 50.0 0.0 0.0 0.0 0.0 0.1 0.9 0.4 0.9 1.3 26.2 6.9 0.0 0.6 1.2 0.6 89.3 22.8 0.7 2.3 36.0 27.9 37.5 43.0 23.6 0.5 66.3 25.8 0.0 2.1 0.2 0.1 0.0 0.0 16.9 11.6 0.0 0.0 8.3 1.8 44.5 1.7 101.8 1.8 0.0 0.0 1.8 4.7 45.7 40.4 2.6 8.7 1.1 0.0 1.1 4.7 22.8 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 0.0 21.2 0.0 63.5 0.0 0.9 0.8 0.0 0.7 0.3 0.7 0.8 0.0 0.2 0.1 0.2 0.3 2.0 0.0 0.0 0.9 0.5 1.7 2.0 1.7 3.2 2.7 2.4 0.8 1.1 0.8 0.8 2.5 0.7 0.3 0.0 1.1 0.7 2.2 1.0 1.3 8.7 1.2 1.1 1.1 0.3 0.3 0.0 13.6 9.2 0.0 265.5 1.6 17.2 11.7 0.6 0.7 9.8 0.1 0.8 4.2 8.0 4.9 2.0 7.6 0.9 1.5 0.7 6.3 0.1 3.9 205.7 16.4 1.7 6.6 18.9 10.2 3.2 0.3 0.9 0.3 1.2 0.0 1.0 0.0 0.6 1.0 0.0 0.4 1.4 26.6 0.0 0.8 3.3 81.0 198.9 70.2 1.9 0.0 0.0 1.0 4.4 4.2 5.1 0.3 54.9 4.6 0.2 25.9 4.9 SLC28A2 "CNT2, HCNT2, HsT17153, SPNT1" ENSG00000137860 "Solute carrier family 28 member 2" O43868 15 45252234-45277846 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 92.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.6;Paneth cells: 35.7;Proximal enterocytes: 43.4;Undifferentiated cells: 48.9" "Cancer enhanced" "Detected in many" "stomach cancer: 3.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046068, HPA055623" Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA046068: AB_2679523, HPA055623: AB_2682866" "unprognostic (2.75e-1)" "unprognostic (2.34e-2)" "unprognostic (1.62e-3)" "unprognostic (5.46e-2)" "unprognostic (1.13e-1)" "unprognostic (6.85e-2)" "unprognostic (6.31e-2)" "unprognostic (1.59e-2)" "unprognostic (1.61e-1)" "unprognostic (6.40e-4)" "unprognostic (3.34e-3)" "unprognostic (2.63e-1)" "unprognostic (1.28e-2)" "unprognostic (2.74e-1)" "unprognostic (2.24e-1)" "unprognostic (1.44e-2)" "unprognostic (8.95e-2)" 0.1 0.3 0.4 0.7 0.4 0.1 0.0 0.3 0.4 2.6 0.0 9.5 68.0 0.5 0.4 0.1 0.1 9.8 0.3 0.3 0.1 3.5 0.8 0.1 0.3 0.4 0.0 0.3 0.3 0.0 0.0 0.6 0.4 0.1 34.6 0.7 0.2 0.0 0.3 0.3 92.3 0.0 0.1 0.2 22.8 0.4 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.3 0.4 0.3 0.1 0.4 0.0 0.4 0.1 0.2 0.6 0.5 0.0 8.1 1.6 0.9 0.1 0.4 0.4 0.0 2.9 0.3 0.0 0.7 8.6 4.5 0.0 2.1 12.3 0.3 19.6 0.0 0.1 0.7 1.0 0.4 1.0 13.9 2.7 1.8 0.0 2.7 1.0 4.6 1.2 8.8 0.7 0.7 0.3 0.9 1.7 1.5 14.5 0.0 0.3 0.4 0.4 0.0 1.3 0.0 0.0 0.2 1.0 2.1 2.0 2.0 0.0 35.7 0.7 0.4 0.2 43.4 1.2 4.6 6.6 0.0 0.3 0.2 2.4 2.1 0.0 0.3 4.7 1.3 0.2 48.9 0.2 SLC2A4RG "GEF, HDBP1, Si-1-2, Si-1-2-19" ENSG00000125520 "SLC2A4 regulator" Q9NR83 20 63739776-63744050 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 150.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 116.2;Proximal tubular cells: 160.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063050 Approved "Nuclear speckles" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA063050: AB_2684930" "unprognostic (2.89e-2)" "unprognostic (2.32e-1)" "unprognostic (1.84e-2)" "unprognostic (5.78e-2)" "unprognostic (2.07e-3)" "unprognostic (6.48e-3)" "unprognostic (2.70e-1)" "unprognostic (1.96e-2)" "unprognostic (1.31e-1)" "unprognostic (3.44e-2)" "unprognostic (2.09e-3)" "unprognostic (1.50e-1)" "unprognostic (1.39e-2)" "unprognostic (1.41e-1)" "unprognostic (1.12e-1)" "unprognostic (1.50e-3)" "unprognostic (3.22e-1)" 59.4 37.9 8.8 3.1 8.6 10.2 45.0 7.3 12.8 42.0 7.7 55.5 1.6 39.2 4.2 47.7 35.0 3.3 60.5 8.3 8.4 67.8 150.6 30.9 5.0 8.4 8.2 45.8 28.4 5.6 23.0 2.8 7.6 50.1 1.5 2.3 27.3 10.5 88.2 60.8 25.6 3.3 8.6 35.5 33.4 24.2 8.2 6.3 32.1 18.7 3.0 50.2 40.6 8.6 20.5 26.4 12.2 11.0 7.6 14.9 11.9 16.6 16.4 43.8 15.2 49.0 34.0 4.3 23.1 12.1 18.9 24.1 6.1 20.0 7.6 13.5 11.0 4.3 19.4 25.8 16.2 10.5 8.9 17.4 29.0 11.8 9.5 8.7 12.8 3.9 15.8 4.7 21.3 37.0 5.9 29.8 5.3 21.9 59.6 29.4 21.8 10.5 17.3 7.8 10.8 19.0 35.4 16.0 4.5 4.6 37.9 33.7 11.0 43.4 22.7 25.2 13.1 12.8 27.0 7.3 18.1 12.4 11.8 0.0 0.0 0.2 0.9 0.0 0.4 0.1 0.9 0.5 0.1 0.0 0.7 0.7 0.0 0.3 0.1 0.2 1.1 0.1 8.8 8.6 7.3 12.8 8.3 8.4 8.4 8.2 7.6 8.6 8.2 8.6 35.9 9.6 21.2 21.5 16.0 24.5 25.0 19.3 19.4 10.1 44.7 61.5 21.3 37.1 11.2 42.3 10.4 30.7 60.1 18.3 78.2 8.2 9.2 16.3 57.1 22.2 2.4 55.4 5.5 10.3 16.6 49.7 12.8 32.4 3.8 52.6 19.6 116.2 14.7 10.1 4.5 17.5 14.2 13.5 12.7 4.3 28.9 14.6 3.6 5.6 11.7 33.5 13.4 8.0 7.1 20.3 7.8 34.6 16.9 14.9 10.5 160.8 6.1 6.5 32.9 26.1 32.9 1.1 6.4 29.3 37.8 8.6 46.3 77.0 15.0 18.3 SLC30A10 "DKFZp547M236, ZnT-10, ZNT8, ZRC1" ENSG00000196660 "Solute carrier family 30 member 10" Q6XR72 1 219685427-219958647 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant, Dystonia, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 23.9;liver: 33.5" "Cell type enhanced" "Detected in some" "Astrocytes: 20.2;Distal enterocytes: 44.3;Early spermatids: 38.3;Hepatocytes: 21.1;Late spermatids: 36.1;Paneth cells: 14.4;Proximal enterocytes: 13.6" "Cancer enriched" "Detected in some" 14 "liver cancer: 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 2.0;HEL: 1.5;K-562: 1.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064547 Enhanced NA NA "Cluster 42: Non-specific - Transcription" "Cluster 45: Intestine - Brush border" "Cluster 1: K-562 - Erythropoiesis" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA064547: AB_2732715" "unprognostic (7.88e-2)" "unprognostic (1.07e-2)" "unprognostic (1.02e-1)" "unprognostic (7.25e-2)" "unprognostic (1.75e-2)" "unprognostic (3.74e-3)" "unprognostic (6.96e-2)" "unprognostic (3.72e-2)" "unprognostic (1.41e-1)" "unprognostic (1.95e-2)" "unprognostic (5.10e-2)" "unprognostic (3.10e-3)" "unprognostic (4.47e-7)" "unprognostic (3.16e-1)" "unprognostic (6.11e-2)" "unprognostic (6.19e-3)" "unprognostic (5.72e-2)" 0.0 0.0 6.0 0.0 6.1 0.3 0.0 4.4 7.6 0.0 7.4 3.8 23.9 0.0 0.0 0.0 0.0 0.4 0.0 5.9 5.7 0.0 33.5 0.0 0.0 5.4 5.9 0.2 0.0 0.0 0.0 0.0 5.6 0.1 5.0 0.4 0.0 0.0 0.7 0.1 8.9 0.0 4.5 0.0 0.0 0.7 6.5 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.2 0.1 0.2 0.2 0.2 0.1 0.1 0.1 0.2 0.2 0.2 0.3 0.3 0.3 0.2 0.1 0.1 6.0 6.1 4.4 7.6 5.9 5.7 5.4 5.9 5.6 4.5 6.5 4.7 0.0 0.0 0.0 20.2 0.2 0.3 0.0 0.2 0.0 0.3 0.2 0.0 1.2 1.5 0.1 0.0 0.0 0.1 0.0 44.3 0.0 0.2 38.3 0.0 0.0 1.0 0.0 2.7 4.3 0.0 0.3 0.1 0.0 0.0 0.0 0.5 0.4 21.1 0.1 0.0 4.3 0.6 0.0 0.6 0.3 36.1 1.2 0.0 1.8 9.4 0.0 3.1 0.0 3.0 3.3 0.0 14.4 1.5 0.0 0.0 13.6 0.0 0.0 0.1 0.0 0.0 0.1 1.8 0.9 0.0 0.1 0.3 0.0 1.3 0.8 0.0 SLC35A3 ENSG00000117620 "Solute carrier family 35 member A3" Q9Y2D2 1 99969351-100035634 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Autism spectrum disorder, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 211.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015253 Uncertain NA NA "Cluster 6: Non-specific - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA015253: AB_1857106" "unprognostic (1.05e-1)" "unprognostic (2.69e-1)" "unprognostic (1.57e-3)" "unprognostic (5.89e-2)" "unprognostic (9.64e-2)" "unprognostic (1.61e-1)" "unprognostic (1.72e-1)" "unprognostic (4.02e-2)" "unprognostic (2.59e-2)" "unprognostic (1.47e-1)" "unprognostic (1.76e-3)" "unprognostic (1.69e-1)" "unprognostic (1.02e-1)" "unprognostic (1.49e-3)" "unprognostic (2.32e-1)" "unprognostic (2.73e-2)" "unprognostic (9.34e-2)" 11.6 7.3 4.3 10.4 5.1 11.4 18.3 6.6 5.8 19.1 10.0 53.3 49.7 9.6 11.4 14.4 13.1 13.5 5.5 4.1 4.7 21.3 37.3 11.5 8.0 4.7 4.6 8.1 11.5 19.8 4.8 10.2 5.1 23.0 53.8 6.9 22.0 11.6 4.9 10.8 41.4 8.8 4.5 7.9 33.4 2.8 4.9 18.9 24.9 6.1 8.9 10.5 10.2 6.3 28.3 7.6 6.7 7.1 14.8 12.9 26.7 24.5 14.8 9.4 13.6 4.9 15.1 15.1 30.0 14.3 13.3 16.0 12.7 11.0 21.6 18.7 9.4 13.7 10.7 11.8 9.2 22.1 1.6 6.8 12.1 11.5 22.2 11.3 11.1 11.9 23.0 21.9 19.3 7.1 14.6 11.4 8.2 16.0 24.9 4.5 20.4 9.4 17.1 16.0 8.6 4.8 17.0 32.3 13.7 6.2 19.7 16.6 13.0 14.3 13.0 32.0 13.3 12.9 16.2 11.2 23.0 13.5 6.1 4.4 2.1 1.1 2.2 2.1 2.5 2.5 2.2 2.6 1.7 1.8 2.7 2.3 0.6 4.3 1.7 5.0 2.8 1.9 4.3 5.1 6.6 5.8 4.1 4.7 4.7 4.6 5.1 4.5 4.9 6.3 23.5 80.1 28.6 12.4 17.8 25.0 21.6 30.5 18.8 15.7 33.9 15.4 8.8 27.1 50.5 55.2 20.9 19.4 51.4 211.0 7.9 18.1 4.4 49.4 22.4 20.5 19.8 9.7 24.4 15.3 30.5 17.0 43.3 46.3 17.1 19.5 20.7 49.3 14.2 10.1 26.6 110.6 22.4 17.8 17.1 2.1 13.4 14.2 8.8 23.4 18.0 19.0 14.4 30.2 46.7 21.7 82.8 13.2 25.6 43.3 112.4 25.3 92.6 25.1 6.6 14.4 17.7 16.2 8.3 21.2 29.7 23.3 23.8 12.8 116.4 48.4 SLC39A11 C17orf26 ENSG00000133195 "Solute carrier family 39 member 11" Q8N1S5 17 72645949-73092712 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 205.3;Excitatory neurons: 107.7;Oligodendrocytes: 360.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 217.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021455 Approved Nucleoplasm NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA021455: AB_2670710" "unprognostic (2.29e-2)" "unprognostic (2.75e-1)" "unprognostic (1.25e-1)" "unprognostic (2.19e-1)" "unprognostic (1.61e-1)" "unprognostic (1.82e-2)" "unprognostic (1.19e-1)" "unprognostic (3.44e-2)" "unprognostic (1.72e-1)" "unprognostic (1.37e-1)" "unprognostic (3.45e-3)" "unprognostic (2.30e-1)" "unprognostic (1.57e-3)" "unprognostic (5.26e-2)" "unprognostic (1.17e-1)" "unprognostic (4.96e-3)" "unprognostic (3.85e-2)" 12.6 7.8 14.0 10.8 27.8 21.2 17.4 22.5 17.2 14.9 9.5 24.0 20.3 5.5 15.7 15.5 9.1 11.0 4.9 14.1 17.9 13.4 39.4 10.9 8.8 25.7 23.7 3.4 29.3 4.7 2.9 8.7 24.0 7.7 24.1 2.3 30.3 8.0 4.5 14.2 22.8 7.3 16.9 7.9 48.2 6.8 23.9 5.5 36.1 3.5 12.4 12.5 9.3 35.3 20.5 36.8 4.3 17.2 30.7 24.8 24.4 21.6 19.0 9.7 13.0 13.7 90.7 25.4 21.5 22.1 15.4 17.2 6.2 10.9 14.8 27.6 12.8 23.8 9.9 16.3 18.3 25.4 217.5 21.2 20.3 20.1 11.6 10.6 10.1 13.1 12.6 31.0 12.4 28.9 16.3 55.1 3.5 62.4 15.6 10.9 16.3 21.5 16.0 20.9 10.2 13.8 11.6 84.7 12.7 16.8 58.4 34.9 8.5 19.0 17.7 16.3 13.4 24.9 12.2 17.9 30.8 50.6 11.1 19.3 39.9 26.0 16.7 40.4 10.9 16.7 12.5 12.5 37.9 9.8 8.8 12.1 6.6 22.6 33.1 26.8 17.1 18.1 14.0 27.8 22.5 17.2 14.1 17.9 25.7 23.7 24.0 16.9 23.9 35.3 4.9 0.0 6.3 205.3 7.6 4.5 5.3 5.6 10.2 2.6 13.7 5.5 2.3 4.3 8.6 3.7 0.0 5.6 6.9 15.8 0.0 9.4 18.5 5.6 3.6 4.0 8.4 9.9 107.7 14.1 17.4 4.7 29.0 9.5 29.9 7.9 3.6 30.1 26.3 5.0 32.1 79.0 10.2 21.0 5.6 66.7 4.1 14.4 10.6 64.6 19.6 4.1 8.2 22.6 360.3 9.1 20.5 3.4 15.1 6.0 24.8 11.5 7.8 1.6 13.1 2.6 7.1 2.0 2.9 10.3 4.4 4.9 5.4 4.4 18.3 7.5 SLC41A2 DKFZP434K0427 ENSG00000136052 "Solute carrier family 41 member 2" Q96JW4 12 104802553-104958744 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 114.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 100.6;Hepatocytes: 51.6;Inhibitory neurons: 93.8;Oligodendrocyte precursor cells: 55.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 10 "myeloid DC: 4.1;plasmacytoid DC: 12.2" "Lineage enriched" "Detected in single" 15 "dendritic cells: 12.2" "Cell line enhanced" "Detected in many" "HDLM-2: 56.2;SK-BR-3: 44.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038658 Approved NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA038658: AB_10671747" "unprognostic (7.19e-2)" "unprognostic (4.38e-3)" "unprognostic (1.94e-2)" "unprognostic (2.38e-1)" "unprognostic (6.06e-3)" "unprognostic (3.05e-2)" "prognostic favorable (9.94e-4)" "unprognostic (1.35e-1)" "unprognostic (3.68e-1)" "unprognostic (3.65e-1)" "unprognostic (4.20e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (3.35e-4)" "unprognostic (1.50e-1)" "unprognostic (1.04e-1)" "unprognostic (1.72e-2)" "unprognostic (5.30e-2)" 8.6 8.7 4.5 8.1 5.9 1.3 10.3 6.0 6.1 9.4 9.1 21.0 31.4 4.6 15.8 1.9 3.2 14.4 2.4 4.8 9.9 8.3 114.9 6.5 4.8 1.5 3.6 5.3 18.3 8.6 6.3 3.7 4.3 3.2 15.1 1.9 14.2 9.4 0.7 1.4 27.8 8.6 0.3 3.2 37.1 8.5 9.0 2.8 12.1 1.6 4.7 5.6 1.6 3.1 11.6 25.6 0.9 5.3 21.0 15.2 9.9 7.9 12.9 5.4 9.1 16.1 10.8 4.7 8.4 15.8 19.8 1.1 5.7 2.6 10.1 56.2 14.4 0.4 9.6 7.3 4.6 1.8 6.2 5.2 2.1 5.8 1.6 11.7 7.0 3.1 0.3 11.9 0.9 5.3 2.3 0.1 2.4 20.6 8.2 1.0 11.0 11.2 21.5 0.3 10.1 2.6 13.5 44.5 2.2 3.9 17.3 0.1 2.0 8.2 5.8 8.7 9.0 14.1 19.1 6.2 13.0 0.9 5.7 0.2 0.2 0.0 0.1 0.1 0.8 0.5 0.1 0.1 4.1 0.2 0.3 0.1 0.2 0.3 0.0 12.2 0.1 0.3 4.5 5.9 6.0 6.1 4.8 9.9 1.5 3.6 4.3 0.3 9.0 3.1 3.8 19.2 9.6 16.6 4.5 2.4 3.2 1.8 1.8 2.6 6.3 2.3 0.8 25.8 6.5 7.3 0.0 1.7 4.4 34.0 0.0 27.9 29.5 6.4 2.5 2.5 1.2 0.0 100.6 38.5 19.7 12.3 29.0 16.7 0.0 0.4 1.8 51.6 5.3 5.0 93.8 9.8 2.0 2.9 33.2 5.9 2.1 8.5 0.0 10.3 18.7 1.8 1.0 55.3 5.2 29.9 9.2 6.4 6.9 4.9 37.0 7.4 3.1 0.1 0.0 4.7 4.8 6.4 4.3 0.2 2.3 9.0 2.2 0.5 11.8 4.9 SLC5A1 "D22S675, NAGT, SGLT1" ENSG00000100170 "Solute carrier family 5 member 1" P13866 22 32043261-32113029 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sugar transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 528.1" "Cell type enriched" "Detected in many" 6 "Proximal enterocytes: 768.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "OE19: 34.2" "Region enriched" "Detected in single" 26 "cerebellum: 7.6" "Low region specificity" "Detected in many" "CAB015467, HPA051805, HPA055106" Enhanced Approved "Nucleoplasm,Nuclear membrane,Golgi apparatus,Cytosol" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Golgi apparatus" "Nuclear membrane, Cytosol" "CAB015467: , HPA051805: AB_2681618, HPA055106: AB_2682695" "unprognostic (1.96e-1)" "unprognostic (1.04e-1)" "unprognostic (2.24e-2)" "prognostic favorable (2.59e-4)" "unprognostic (3.85e-2)" "unprognostic (2.75e-2)" "unprognostic (1.60e-2)" "unprognostic (2.15e-1)" "unprognostic (9.22e-2)" "unprognostic (4.83e-2)" "unprognostic (6.21e-2)" "unprognostic (9.53e-2)" "prognostic favorable (6.97e-7)" "unprognostic (4.68e-3)" "unprognostic (1.98e-1)" "unprognostic (6.00e-2)" "unprognostic (1.45e-2)" 0.1 0.0 0.1 4.2 0.1 0.0 9.7 0.2 0.1 12.3 0.0 10.7 528.1 0.5 3.5 5.1 1.1 26.9 75.2 0.1 0.0 6.6 1.7 2.1 0.3 0.1 0.0 0.0 1.6 0.3 1.0 0.0 0.1 3.0 9.7 0.2 19.0 2.4 0.3 13.5 302.4 0.7 0.0 2.9 7.2 2.3 0.5 0.1 0.0 0.0 4.0 0.0 6.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.6 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 34.2 0.0 0.0 0.0 2.1 0.0 0.0 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.5 0.2 0.1 0.0 0.0 0.3 0.2 0.6 1.7 4.2 0.0 0.0 11.6 6.5 115.2 115.8 8.2 0.0 0.0 0.0 0.2 19.8 0.0 3.0 38.4 2.4 1.4 1.0 25.4 0.0 0.4 1.4 0.0 1.4 5.6 10.3 0.0 0.0 0.0 0.3 0.0 0.0 0.3 34.1 0.0 0.0 0.0 71.3 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 32.6 1.5 0.0 17.6 768.7 6.4 2.0 0.0 0.0 0.0 0.7 10.1 4.2 2.0 5.5 0.0 0.1 0.1 41.2 6.7 SLC5A12 "MGC52019, SMCT2" ENSG00000148942 "Solute carrier family 5 member 12" Q1EHB4 11 26667020-26723427 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 47.7;intestine: 30.1;kidney: 171.7" "Group enriched" "Detected in some" 23 "Proximal enterocytes: 286.0;Proximal tubular cells: 181.0" "Cancer enriched" "Detected in single" 26 "renal cancer: 9.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 2.3;NTERA-2: 1.7;SuSa: 3.3;T-47d: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA060904 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" Nucleoplasm "HPA060904: AB_2684385" "unprognostic (3.69e-3)" "unprognostic (6.92e-2)" "unprognostic (1.79e-1)" "unprognostic (2.86e-1)" "unprognostic (2.01e-2)" "unprognostic (9.35e-3)" "unprognostic (4.21e-3)" "unprognostic (4.49e-2)" "unprognostic (2.36e-3)" "unprognostic (1.71e-1)" "unprognostic (2.03e-2)" "unprognostic (3.43e-1)" "unprognostic (2.91e-3)" "unprognostic (1.34e-1)" "unprognostic (8.53e-2)" "unprognostic (1.42e-2)" "unprognostic (9.40e-3)" 0.1 0.1 0.3 0.0 0.5 0.9 0.1 0.9 0.4 0.0 0.3 0.2 4.9 0.1 47.7 0.0 0.1 0.1 4.3 0.3 0.4 171.7 1.7 0.1 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.6 0.2 0.1 0.2 1.0 0.1 0.1 0.1 0.3 30.1 0.0 0.0 0.6 0.3 0.2 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.5 0.2 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.3 0.0 0.0 0.1 0.2 1.7 0.3 0.0 0.0 0.0 0.3 0.0 0.5 0.8 0.1 0.7 0.1 0.0 3.3 1.2 0.2 0.2 0.2 0.1 0.2 0.1 1.0 0.3 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.5 0.9 0.4 0.3 0.4 0.2 0.1 0.2 0.0 0.2 0.5 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.1 3.7 0.0 0.1 0.0 2.4 9.8 0.0 1.4 0.2 0.0 0.2 0.0 0.0 0.7 0.0 0.2 0.7 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.3 6.7 0.0 0.0 0.0 0.2 0.0 0.7 0.0 1.0 0.0 0.8 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 286.0 181.0 0.1 0.3 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.6 4.5 3.5 0.1 SLC6A13 GAT2 ENSG00000010379 "Solute carrier family 6 member 13" Q9NSD5 12 220621-262873 "Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 153.1" "Cell type enriched" "Detected in some" 6 "Proximal tubular cells: 324.9" "Cancer enriched" "Detected in some" 18 "renal cancer: 32.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "RPTEC TERT1: 4.6;SuSa: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036449, HPA052726" Supported Nucleoplasm,Nucleoli,Mitochondria,Cytosol NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "Nucleoplasm, Nucleoli, Cytosol" "HPA036449: AB_2675130, HPA052726: AB_2681927" "unprognostic (8.45e-3)" "unprognostic (4.20e-1)" "unprognostic (5.44e-2)" "unprognostic (1.64e-5)" "unprognostic (1.13e-1)" "unprognostic (8.02e-2)" "unprognostic (1.32e-2)" "unprognostic (1.30e-1)" "unprognostic (1.75e-1)" "unprognostic (2.15e-1)" "unprognostic (7.21e-4)" "unprognostic (2.93e-1)" "unprognostic (1.25e-3)" "unprognostic (3.79e-2)" "unprognostic (2.62e-1)" "unprognostic (6.23e-2)" "unprognostic (1.91e-1)" 0.2 0.3 13.4 0.0 16.5 0.1 0.1 11.0 20.1 0.1 13.9 0.1 2.6 0.1 0.3 0.0 7.1 0.0 2.6 12.2 11.9 153.1 36.8 0.8 0.0 11.6 12.6 0.2 0.0 0.0 3.0 0.0 11.7 0.5 0.0 1.1 0.1 0.1 0.5 0.2 0.6 0.0 12.1 0.3 0.1 3.1 13.8 0.1 6.3 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.4 1.6 0.0 0.0 0.1 0.0 0.5 0.0 0.2 0.6 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 16.5 11.0 20.1 12.2 11.9 11.6 12.6 11.7 12.1 13.8 11.7 0.0 0.0 0.6 1.3 1.9 0.0 0.0 0.4 0.0 0.4 0.1 0.1 1.5 0.0 0.1 18.4 2.1 0.0 0.1 0.0 49.0 0.0 1.4 0.6 0.1 0.2 0.0 5.3 3.6 0.0 0.0 0.3 0.0 0.6 0.0 0.0 1.8 27.0 0.0 0.0 1.2 0.0 2.0 1.6 0.0 0.6 0.3 1.7 0.0 17.8 0.0 0.0 0.0 1.5 1.3 0.0 0.0 0.0 0.0 0.1 0.5 324.9 0.7 0.7 0.0 0.4 0.1 0.6 0.4 0.0 0.0 0.3 0.9 0.0 0.0 0.0 SLC9A3R2 "E3KARP, NHERF-2, SIP-1, TKA-1" ENSG00000065054 "SLC9A3 regulator 2" Q15599 16 2025356-2039026 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 568.2" "Cell type enhanced" "Detected in many" "Adipocytes: 1013.8;Endothelial cells: 398.9;Hepatic stellate cells: 374.4;Hepatocytes: 227.4;Pancreatic endocrine cells: 326.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.2;intermediate monocyte: 1.6;myeloid DC: 3.9;plasmacytoid DC: 2.9" "Group enriched" "Detected in many" 5 "dendritic cells: 3.9;monocytes: 2.2" "Cell line enhanced" "Detected in many" "A549: 188.6;MCF7: 306.8;PC-3: 281.2;SK-BR-3: 188.3;U-251 MG: 193.6;WM-115: 202.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001672, HPA066520" Enhanced Supported "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA001672: AB_1080017, HPA066520: AB_2732748" "unprognostic (6.99e-2)" "unprognostic (4.56e-2)" "unprognostic (2.06e-2)" "prognostic favorable (1.03e-4)" "unprognostic (1.41e-2)" "unprognostic (1.54e-1)" "unprognostic (2.94e-3)" "unprognostic (9.17e-2)" "unprognostic (1.68e-2)" "unprognostic (1.56e-2)" "unprognostic (2.17e-2)" "unprognostic (1.70e-2)" "unprognostic (2.20e-2)" "unprognostic (6.20e-3)" "unprognostic (9.10e-2)" "unprognostic (2.40e-1)" "unprognostic (2.80e-2)" 234.7 81.7 107.0 20.7 98.6 0.7 181.7 83.4 119.7 92.6 60.6 77.4 27.2 92.7 10.7 47.3 77.7 34.8 568.2 82.4 88.5 207.5 408.3 289.1 22.0 96.4 95.5 57.9 47.7 24.0 95.6 51.3 99.3 129.1 11.9 3.0 149.1 42.4 144.6 45.3 81.2 18.8 87.0 143.8 109.5 36.3 116.2 7.9 188.4 109.0 7.4 77.4 72.6 94.7 32.5 188.6 5.0 38.6 6.2 8.6 5.7 138.1 81.9 67.9 22.5 25.4 41.9 0.1 63.4 59.2 9.1 30.9 15.0 13.7 7.1 0.4 45.0 3.1 80.8 61.6 44.3 0.5 13.9 9.2 13.7 20.2 5.9 32.1 68.2 15.0 24.0 2.9 4.8 306.8 0.6 35.7 7.5 76.8 281.2 27.6 8.1 50.5 16.0 2.9 35.3 33.1 9.7 188.3 12.8 5.0 152.6 16.8 176.4 21.5 30.7 1.9 193.6 5.1 4.6 0.7 2.5 3.6 202.4 0.0 2.2 0.0 0.5 1.6 0.2 0.0 0.1 0.1 3.9 0.0 0.4 0.5 0.0 0.0 0.5 2.9 0.1 0.7 107.0 98.6 83.4 119.7 82.4 88.5 96.4 95.5 99.3 87.0 116.2 94.7 1013.8 3.2 10.5 4.2 7.3 15.2 19.6 17.1 7.4 2.6 79.5 65.0 25.5 88.6 47.3 12.9 0.0 1.0 11.4 13.3 5.9 36.1 16.1 37.2 36.8 398.9 21.5 17.3 3.4 8.8 0.8 53.5 33.6 67.8 0.0 5.1 374.4 227.4 2.6 3.3 5.5 77.0 22.4 30.9 35.1 35.8 82.0 7.0 33.8 31.9 2.2 17.2 7.2 4.0 3.6 326.8 9.3 44.4 4.9 51.8 1.2 14.7 27.3 5.0 26.3 22.3 69.1 7.0 15.4 3.4 11.4 1.0 8.8 9.5 18.0 66.6 SLCO1B1 "LST-1, OATP-C, OATP1B1, SLC21A6" ENSG00000134538 "Solute carrier organic anion transporter family member 1B1" Q9Y6L6 12 21131194-21239796 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 614 "liver: 537.2" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 83.1" "Cancer enriched" "Detected in some" 96 "liver cancer: 52.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 1.1;NTERA-2: 1.3;RPMI-8226: 1.8;SuSa: 2.2" "HPA050892, HPA073093" Supported Supported "Plasma membrane" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 5: NTERA-2 - Transcription" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "HPA050892: AB_2681265, HPA073093: " "unprognostic (5.45e-1)" "unprognostic (1.82e-4)" "unprognostic (2.43e-3)" "unprognostic (1.96e-3)" "unprognostic (1.80e-1)" "unprognostic (2.41e-1)" "unprognostic (8.82e-2)" "unprognostic (5.63e-2)" "unprognostic (3.86e-2)" "unprognostic (3.49e-1)" 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 537.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.2 0.1 0.2 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 83.1 0.0 0.0 0.2 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 SLCO2B1 "OATP-B, OATP2B1, SLC21A9" ENSG00000137491 "Solute carrier organic anion transporter family member 2B1" O94956 11 75100563-75206549 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 229.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 204.5;Hofbauer cells: 122.2;Kupffer cells: 155.8;Macrophages: 92.4;Microglial cells: 232.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 90.3;GAMG: 21.2;Hep G2: 20.4;HMC-1: 25.8;OE19: 111.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020659 Uncertain NA NA "Cluster 15: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 4: Macrophages - Innate immune response" "HPA020659: AB_1857219" "unprognostic (8.25e-2)" "unprognostic (5.30e-2)" "unprognostic (2.02e-2)" "unprognostic (3.57e-1)" "unprognostic (3.40e-1)" "unprognostic (1.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.09e-1)" "unprognostic (2.61e-1)" "unprognostic (2.00e-3)" "unprognostic (1.99e-1)" "unprognostic (2.09e-1)" "unprognostic (9.75e-3)" "unprognostic (2.54e-2)" "unprognostic (4.57e-3)" "unprognostic (1.04e-1)" "unprognostic (3.87e-2)" 39.9 31.5 40.1 34.0 35.9 2.9 12.1 34.0 37.4 18.1 21.3 30.9 42.1 9.5 3.6 19.7 13.2 28.4 15.6 31.9 47.2 21.0 229.6 60.7 60.1 75.7 53.4 9.4 22.1 7.9 5.1 43.9 63.0 6.1 23.6 1.5 8.4 9.6 5.6 4.3 51.3 26.3 49.7 46.4 15.0 6.0 80.4 16.7 10.1 8.0 28.5 26.3 6.2 55.1 0.0 0.7 2.8 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 90.3 0.0 0.1 0.1 0.0 21.2 0.2 0.0 0.0 0.0 1.1 0.0 15.0 1.0 20.4 0.0 1.1 25.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.3 8.7 0.0 0.1 0.0 0.1 0.1 111.1 0.0 0.0 2.4 9.6 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.8 0.0 0.0 1.9 0.0 0.1 0.3 0.0 1.5 1.8 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.1 35.9 34.0 37.4 31.9 47.2 75.7 53.4 63.0 49.7 80.4 55.1 4.7 0.0 8.9 1.3 0.7 1.9 0.0 0.0 1.8 3.4 0.9 1.4 2.8 11.5 1.8 0.0 0.0 0.9 0.1 14.7 1.9 0.0 2.8 0.0 0.1 28.8 0.0 2.7 0.5 0.2 2.3 3.6 0.5 0.0 22.9 6.1 3.6 204.5 122.2 0.0 0.5 6.6 0.0 155.8 8.9 1.7 10.8 92.4 0.0 232.3 2.0 0.2 0.0 1.5 0.6 0.1 14.6 10.5 1.4 0.0 46.7 8.2 0.7 0.7 0.0 3.0 1.1 0.4 0.2 4.5 0.4 2.5 0.7 0.4 13.3 0.1 SMIM14 "C4orf34, FLJ13289" ENSG00000163683 "Small integral membrane protein 14" Q96QK8 4 39546336-39638902 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 118.4" "Cell type enhanced" "Detected in all" "Hepatocytes: 553.9;Intestinal goblet cells: 408.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 269.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051299 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 2: Hepatocytes - Metabolism" "HPA051299: AB_2681429" "unprognostic (3.13e-1)" "unprognostic (1.29e-1)" "unprognostic (1.64e-2)" "prognostic favorable (2.63e-4)" "unprognostic (6.48e-2)" "prognostic favorable (3.00e-6)" "prognostic favorable (3.47e-4)" "unprognostic (2.67e-2)" "unprognostic (1.54e-1)" "unprognostic (8.30e-2)" "unprognostic (1.22e-1)" "unprognostic (7.18e-2)" "prognostic favorable (2.07e-4)" "unprognostic (6.66e-2)" "unprognostic (1.33e-1)" "unprognostic (9.50e-2)" "unprognostic (4.92e-3)" 21.7 45.5 12.6 22.4 15.7 4.7 33.2 15.0 14.8 36.2 14.8 41.4 17.7 19.2 38.4 20.0 27.5 19.8 10.2 13.3 17.4 22.9 118.4 22.4 38.9 15.6 15.1 23.2 24.3 25.4 17.5 8.4 16.6 35.6 36.8 12.3 40.8 19.8 6.7 14.3 21.1 14.5 16.7 27.2 46.6 14.2 15.9 15.5 27.9 9.4 45.2 19.4 14.5 19.4 12.4 20.9 9.9 9.6 64.4 71.8 17.7 16.9 21.5 7.4 10.8 6.8 44.2 269.3 15.8 19.2 11.8 4.6 2.0 3.6 6.1 7.1 2.2 0.3 8.9 12.2 22.0 1.8 2.8 27.4 13.1 7.6 4.9 26.4 11.3 11.8 2.9 8.6 12.5 38.4 2.9 4.8 4.7 54.2 14.4 11.9 0.5 3.0 15.5 10.8 7.5 9.4 19.0 25.1 6.8 3.9 25.1 4.0 37.8 17.0 3.8 22.1 2.9 28.0 6.4 1.1 27.9 3.4 6.7 53.5 52.7 28.0 20.7 46.0 22.6 103.9 14.5 18.4 55.9 107.1 11.0 16.2 37.3 40.4 49.1 100.1 9.1 44.5 12.6 15.7 15.0 14.8 13.3 17.4 15.6 15.1 16.6 16.7 15.9 19.4 55.3 57.7 124.4 29.4 228.9 49.3 76.5 83.4 42.7 80.6 150.3 96.6 17.0 65.8 143.4 104.8 35.5 38.3 74.9 242.2 84.1 86.9 238.5 115.3 65.6 45.8 106.1 25.3 34.0 144.8 49.6 108.6 85.1 73.4 45.7 19.2 57.1 553.9 43.6 92.5 52.4 408.8 126.1 79.8 85.1 31.5 113.1 62.6 46.2 36.5 108.0 109.7 36.0 29.1 85.5 226.2 132.4 124.5 19.8 199.0 75.0 117.9 225.3 48.5 59.2 56.5 58.8 66.2 25.0 95.0 59.8 104.1 28.8 65.7 118.3 124.0 SMLR1 ENSG00000256162 "Small leucine rich protein 1" H3BR10 6 130827406-130837135 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 56.6" "Group enriched" "Detected in some" 11 "Hepatocytes: 243.3;Proximal enterocytes: 144.8" "Cancer enriched" "Detected in some" 20 "liver cancer: 16.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "Hep G2: 81.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA066060 Uncertain NA NA "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA066060: AB_2685607" "unprognostic (1.73e-1)" "unprognostic (7.37e-3)" "unprognostic (1.43e-1)" "unprognostic (1.32e-2)" "unprognostic (2.35e-1)" "unprognostic (1.31e-1)" "unprognostic (1.50e-1)" "unprognostic (6.43e-3)" "unprognostic (2.68e-3)" "unprognostic (3.29e-1)" 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 3.2 56.6 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 81.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.1 10.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 14.7 1.4 243.3 0.1 0.0 0.0 3.1 0.0 5.2 0.0 0.2 0.0 0.1 0.0 2.8 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 144.8 17.5 0.0 1.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 2.0 1.5 0.0 SNAP47 "C1orf142, SNAP-47, SVAP1" ENSG00000143740 "Synaptosome associated protein 47" Q5SQN1 1 227728200-227781826 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 95.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028167 Supported Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 89: Fibroblasts - ECM organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA028167: AB_10603032" "unprognostic (3.31e-2)" "unprognostic (1.31e-1)" "unprognostic (1.93e-2)" "unprognostic (7.31e-2)" "unprognostic (4.88e-2)" "unprognostic (2.23e-2)" "unprognostic (1.20e-1)" "unprognostic (7.28e-2)" "unprognostic (1.48e-1)" "unprognostic (2.07e-1)" "unprognostic (1.34e-2)" "unprognostic (7.26e-2)" "unprognostic (1.48e-1)" "unprognostic (6.14e-2)" "unprognostic (4.81e-1)" "unprognostic (1.11e-1)" "unprognostic (2.05e-1)" 14.2 43.8 19.8 10.0 22.0 10.1 16.9 18.3 23.8 23.9 12.5 20.5 10.1 28.9 15.3 14.0 25.9 12.4 38.6 22.4 17.0 19.4 27.0 11.7 18.1 14.4 15.4 47.2 16.5 23.5 27.4 20.1 15.2 17.3 8.9 12.9 18.2 12.1 36.3 16.6 15.3 18.5 15.3 14.6 17.0 38.6 16.7 17.1 17.1 23.4 14.1 19.9 14.7 17.7 33.5 44.2 27.2 27.7 30.3 25.1 35.0 21.2 33.7 35.5 26.5 29.4 29.8 23.8 37.9 33.2 27.3 36.2 33.6 37.9 27.6 48.1 63.4 19.8 28.0 18.9 21.6 30.8 17.8 28.0 32.2 43.3 24.7 28.3 29.4 28.7 37.6 23.7 32.1 22.0 31.5 29.0 44.3 42.5 65.1 32.8 32.3 37.7 20.4 28.1 50.5 32.1 33.6 44.0 33.5 26.4 55.1 27.8 21.3 30.9 38.4 30.7 52.5 30.2 23.2 28.9 28.0 23.0 40.8 19.1 21.0 34.0 29.4 21.2 28.3 22.6 33.1 34.2 23.3 21.3 27.1 25.4 7.4 30.5 27.7 24.0 46.4 25.4 19.8 22.0 18.3 23.8 22.4 17.0 14.4 15.4 15.2 15.3 16.7 17.7 10.1 6.4 13.1 9.4 16.1 13.4 15.9 16.2 16.5 30.8 16.5 14.7 13.0 22.8 13.2 14.7 27.1 24.3 18.7 8.7 35.2 19.9 49.4 7.2 14.3 11.7 16.2 13.5 12.0 18.2 28.4 15.1 10.7 6.9 5.7 21.0 11.0 13.8 16.3 42.1 9.6 8.6 22.4 8.8 6.2 95.9 25.7 7.6 12.4 8.4 22.3 30.5 45.3 6.6 6.1 17.0 3.3 20.7 22.7 16.5 12.4 15.8 8.9 33.5 13.1 12.0 14.0 41.9 26.4 8.5 15.3 27.5 19.4 23.3 10.5 10.1 SNCA "NACP, PARK1, PARK4, PD1" ENSG00000145335 "Synuclein alpha" P37840 4 89700345-89838315 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Alzheimer disease, Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "bone marrow: 273.6;brain: 128.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 1225.0;Excitatory neurons: 251.5;Melanocytes: 352.2;Oligodendrocytes: 195.4" "Cancer enriched" "Detected in many" 8 "melanoma: 37.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 102.9" "Group enriched" "Detected in all" 4 "dendritic cells: 102.9;granulocytes: 51.5;monocytes: 66.9" "Cell line enhanced" "Detected in many" "HEL: 221.5;HUVEC TERT2: 269.8;RT4: 137.3;SK-MEL-30: 271.6;TIME: 311.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005459, CAB010877" Enhanced "Intracellular and membrane" NA NA 28000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 6: Erythroid cells - Oxygen transport" "CAB010877: AB_261518, HPA005459: AB_2667324" "unprognostic (4.80e-2)" "unprognostic (1.52e-1)" "unprognostic (8.13e-2)" "unprognostic (1.05e-3)" "unprognostic (2.65e-2)" "unprognostic (1.54e-2)" "unprognostic (1.78e-2)" "unprognostic (3.44e-2)" "unprognostic (1.73e-2)" "unprognostic (3.85e-3)" "unprognostic (1.01e-3)" "unprognostic (2.09e-2)" "unprognostic (1.57e-1)" "unprognostic (2.51e-3)" "unprognostic (1.68e-1)" "unprognostic (3.93e-4)" "unprognostic (7.48e-3)" 16.0 9.9 91.5 10.0 112.2 273.6 7.8 47.2 128.2 26.1 16.1 28.5 3.3 34.3 3.4 8.5 11.2 5.4 20.9 115.2 69.1 12.4 2.9 16.6 2.2 97.5 88.3 29.3 2.2 1.1 28.7 28.3 89.9 17.3 6.9 20.3 15.9 9.7 1.2 16.4 8.6 33.3 36.0 15.2 6.4 3.2 76.2 5.3 10.2 8.5 4.8 9.3 23.2 107.0 0.5 1.0 40.1 0.0 0.7 0.0 0.6 0.4 44.5 1.6 3.0 0.0 0.0 0.2 12.0 0.0 0.0 9.3 53.6 97.7 1.5 0.0 22.6 221.5 115.4 0.5 84.2 0.0 1.4 2.1 38.2 0.0 109.5 117.3 269.8 2.2 2.0 0.6 0.2 0.0 2.1 0.3 10.6 0.2 4.8 0.0 15.8 0.0 0.3 137.3 23.2 15.6 0.2 0.3 271.6 29.0 0.0 0.4 311.4 1.3 8.0 0.1 0.8 0.2 0.2 0.1 8.8 0.2 87.4 51.5 66.9 0.1 0.3 27.7 0.1 4.2 1.9 0.3 84.6 1.7 1.0 0.5 11.1 17.3 8.2 102.9 0.0 63.7 91.5 112.2 47.2 128.2 115.2 69.1 97.5 88.3 89.9 36.0 76.2 107.0 1.8 0.0 0.6 40.1 2.6 76.6 16.3 173.4 101.3 10.4 0.9 14.4 13.4 0.0 21.5 11.0 0.0 10.1 10.1 0.1 1.9 0.0 0.6 0.3 1.1 19.4 1.8 1225.0 251.5 0.2 1.9 32.7 0.0 0.3 0.0 23.9 7.5 0.8 62.3 10.1 53.8 0.0 44.7 17.2 64.2 1.5 2.1 100.7 352.2 76.8 24.4 19.4 4.1 95.5 195.4 0.2 0.0 0.0 0.5 11.3 0.0 2.0 6.6 7.4 13.1 0.5 5.3 19.6 16.9 4.5 22.6 3.4 3.8 43.6 0.0 3.4 SNED1 "FLJ00133, Snep, SST3" ENSG00000162804 "Sushi, nidogen and EGF like domains 1" Q8TER0 2 240998618-241095568 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 95.0;Excitatory neurons: 86.0;Leydig cells: 95.1;Microglial cells: 77.8;Peritubular cells: 71.1;Skeletal myocytes: 53.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.9" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 5 "ASC TERT1: 410.4;HSkMC: 211.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036414, HPA036415" Uncertain "Secreted to blood" NA NA 27000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA036414: AB_10960852, HPA036415: AB_10964128" "unprognostic (1.41e-1)" "unprognostic (3.92e-2)" "unprognostic (1.52e-2)" "unprognostic (9.37e-3)" "unprognostic (1.57e-3)" "unprognostic (4.62e-2)" "unprognostic (7.77e-4)" "unprognostic (3.49e-2)" "unprognostic (4.96e-1)" "unprognostic (7.85e-3)" "unprognostic (3.42e-2)" "unprognostic (2.06e-2)" "unprognostic (2.80e-2)" "unprognostic (1.16e-1)" "unprognostic (3.72e-1)" "unprognostic (5.51e-3)" "unprognostic (4.95e-3)" 23.8 9.3 4.2 6.4 8.5 1.2 15.8 14.1 6.9 34.1 32.4 7.3 4.5 18.0 11.8 6.1 21.6 18.7 11.1 10.7 11.7 7.1 8.0 13.3 4.7 8.3 6.4 21.9 7.3 3.1 7.2 1.9 4.8 12.5 3.4 2.5 14.6 7.5 19.8 12.1 10.4 6.3 0.6 14.1 5.7 9.3 2.2 3.3 30.2 9.1 2.9 11.5 10.7 5.9 0.1 0.6 0.4 4.8 61.1 410.4 0.3 2.4 1.5 0.5 0.2 0.2 0.2 0.1 1.0 4.4 0.5 0.2 0.4 0.0 0.3 2.7 1.0 0.2 4.5 0.4 2.6 0.2 0.5 211.6 0.1 0.5 0.3 28.4 9.5 0.2 0.1 2.7 11.5 2.4 1.6 0.2 0.7 0.1 0.3 0.2 8.1 0.1 5.6 0.5 0.8 0.3 1.9 8.3 4.2 0.6 1.8 0.8 23.7 8.7 0.6 50.9 1.5 0.8 0.4 1.5 11.7 0.1 2.6 0.0 0.0 0.0 0.0 0.3 0.3 1.9 0.4 0.2 0.0 0.6 0.2 0.2 0.0 0.0 0.7 0.0 0.4 0.0 4.2 8.5 14.1 6.9 10.7 11.7 8.3 6.4 4.8 0.6 2.2 5.9 8.0 6.4 11.0 95.0 8.4 3.6 0.9 0.4 2.8 2.8 1.1 1.8 2.4 1.5 8.5 5.5 0.0 0.1 0.3 0.3 0.0 1.2 1.3 10.6 16.8 10.9 2.4 3.2 86.0 1.2 0.1 22.1 2.6 10.7 0.0 5.0 22.9 5.8 0.2 1.7 32.5 0.2 0.0 2.9 5.9 5.9 95.1 2.7 1.8 77.8 0.6 7.4 0.0 11.6 7.0 0.7 0.1 71.1 0.9 3.0 0.0 0.5 4.2 1.2 26.3 53.7 4.9 0.6 1.5 0.7 2.6 0.4 1.8 36.4 0.5 0.6 SOAT2 ACAT2 ENSG00000167780 "Sterol O-acyltransferase 2" O75908 12 53103486-53124535 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "intestine: 19.5" "Cell type enriched" "Detected in some" 5 "Proximal enterocytes: 14.3" "Group enriched" "Detected in some" 8 "liver cancer: 5.2;testis cancer: 5.5" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.1" "Lineage enriched" "Detected in single" 5 "T-cells: 1.1" "Group enriched" "Detected in some" 5 "CACO-2: 9.5;Hep G2: 22.6;U-266/70: 7.2" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "unprognostic (2.53e-1)" "unprognostic (2.72e-3)" "unprognostic (1.15e-1)" "unprognostic (1.40e-1)" "unprognostic (1.30e-4)" "unprognostic (3.88e-3)" "unprognostic (9.26e-2)" "unprognostic (4.20e-2)" "unprognostic (1.32e-1)" "unprognostic (3.29e-1)" "unprognostic (1.06e-2)" "unprognostic (2.53e-1)" "unprognostic (1.83e-2)" "unprognostic (9.05e-2)" "unprognostic (2.37e-1)" "unprognostic (7.58e-3)" "unprognostic (3.28e-1)" 0.3 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.1 0.8 0.0 0.2 11.6 0.4 0.2 0.1 0.6 0.4 0.1 0.0 0.0 0.4 2.9 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.4 0.1 0.0 0.4 0.1 0.0 0.3 19.5 0.0 0.0 2.1 0.2 0.2 0.0 0.1 0.2 0.1 0.2 0.3 0.6 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.3 0.4 9.5 0.1 0.0 0.0 0.5 0.0 0.8 0.0 0.0 0.7 0.0 0.0 1.0 0.0 22.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.4 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 7.2 1.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.4 0.7 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 1.5 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 1.3 0.0 0.0 0.0 0.2 0.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 2.5 0.0 0.0 0.0 14.3 0.8 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.6 0.0 0.3 0.0 SOCS3 "CIS3, Cish3, SOCS-3, SSI-3" ENSG00000184557 "Suppressor of cytokine signaling 3" O14543 17 78356778-78360077 "Disease related genes, Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 501.5" "Cell type enhanced" "Detected in many" "Adipocytes: 989.2;Endothelial cells: 635.9;Fibroblasts: 394.4;Langerhans cells: 381.5;Skeletal myocytes: 485.9;Smooth muscle cells: 381.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 9.5" "Group enriched" "Detected in many" 6 "granulocytes: 9.5;T-cells: 3.1" "Cell line enhanced" "Detected in many" "HDLM-2: 154.2;HSkMC: 73.3;U-266/70: 76.0" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "spinal cord: 9.8" "CAB012220, HPA068569" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Plasma membrane" "CAB012220: AB_443287, HPA068569: AB_2686008" "prognostic favorable (4.80e-4)" "unprognostic (2.67e-1)" "unprognostic (5.05e-2)" "unprognostic (1.64e-3)" "unprognostic (4.41e-3)" "unprognostic (2.48e-3)" "unprognostic (1.81e-1)" "unprognostic (1.46e-1)" "unprognostic (6.88e-2)" "unprognostic (9.61e-3)" "unprognostic (1.84e-1)" "unprognostic (2.00e-2)" "prognostic unfavorable (9.34e-9)" "unprognostic (1.08e-2)" "unprognostic (8.80e-2)" "unprognostic (7.59e-3)" "unprognostic (8.40e-2)" 501.5 50.3 19.1 99.0 20.2 126.4 114.1 18.8 27.5 35.1 21.7 119.0 19.4 53.4 1.9 72.7 306.5 190.4 76.8 16.8 21.2 72.1 84.2 234.8 46.9 43.1 22.1 55.5 46.2 23.6 55.7 77.5 24.6 61.8 27.2 4.2 36.3 17.1 26.1 55.3 64.2 125.2 23.7 52.0 123.9 5.9 32.2 115.9 54.1 37.1 11.8 187.9 31.6 19.6 6.4 10.2 7.3 3.8 2.8 44.3 19.1 31.4 28.3 32.1 13.6 6.6 4.4 0.2 6.7 7.5 20.4 2.0 1.5 3.1 12.7 154.2 0.9 5.8 24.1 1.4 14.5 0.1 2.7 73.3 2.6 24.9 9.3 19.4 14.0 0.5 17.4 58.2 15.1 3.3 3.3 1.0 5.2 1.2 12.8 0.2 36.9 1.1 51.4 6.3 0.3 4.6 9.5 2.5 1.3 26.8 2.9 1.4 8.4 62.7 17.6 22.2 18.4 76.0 46.9 0.1 51.6 0.8 4.1 0.0 1.0 0.2 0.8 0.1 1.9 0.0 2.1 0.9 1.1 0.0 3.1 0.6 9.5 0.3 0.0 1.0 1.3 0.5 19.1 20.2 18.8 27.5 16.8 21.2 43.1 22.1 24.6 23.7 32.2 19.6 989.2 48.1 125.6 0.7 64.7 164.3 120.7 75.0 125.2 1.0 176.3 136.4 23.1 18.6 51.7 38.6 2.1 14.9 42.1 20.5 5.9 44.4 0.8 106.7 207.6 635.9 33.0 11.6 0.0 38.6 46.0 394.4 125.4 166.8 36.0 5.8 307.3 20.2 94.6 0.0 0.1 25.0 30.5 78.4 381.5 1.7 78.3 231.0 85.4 1.0 33.6 7.7 1.0 0.0 1.0 43.0 28.1 2.2 115.5 72.0 24.3 11.5 38.1 2.7 13.1 485.9 381.7 0.4 1.0 36.3 133.0 62.1 88.7 5.3 41.0 90.5 SOX17 ENSG00000164736 "SRY-box transcription factor 17" Q9H6I2 8 54457935-54460892 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 49.1" "Group enriched" "Detected in many" 8 "Adipocytes: 464.9;Endometrial ciliated cells: 377.3;Endothelial cells: 171.5;Glandular and luminal cells: 520.0" "Group enriched" "Detected in many" 4 "endometrial cancer: 122.8;ovarian cancer: 96.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "EFO-21: 108.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025594, HPA068399" Enhanced Approved Nucleoplasm NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB025594: , HPA068399: AB_2685981" "unprognostic (1.87e-1)" "unprognostic (1.13e-1)" "unprognostic (1.76e-3)" "prognostic favorable (2.76e-4)" "unprognostic (1.01e-1)" "unprognostic (3.85e-2)" "unprognostic (3.34e-2)" "unprognostic (1.28e-1)" "unprognostic (1.39e-2)" "unprognostic (7.90e-2)" "unprognostic (3.62e-2)" "unprognostic (1.18e-1)" "unprognostic (4.98e-2)" "unprognostic (7.28e-3)" "unprognostic (1.12e-1)" "unprognostic (3.76e-1)" "unprognostic (1.88e-1)" 49.1 1.6 2.9 1.4 2.3 0.0 32.6 2.6 3.3 20.4 1.4 8.3 0.7 18.8 1.2 3.6 23.0 7.7 19.1 2.1 2.2 5.6 1.3 9.9 0.7 2.9 2.5 4.2 1.9 0.8 2.3 5.7 2.7 6.0 0.8 0.1 3.9 1.1 10.3 5.1 5.0 4.3 2.5 13.2 5.7 3.4 2.8 0.4 5.8 5.8 0.4 8.4 9.4 2.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.7 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.3 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 2.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.3 2.6 3.3 2.1 2.2 2.9 2.5 2.7 2.5 2.8 2.6 464.9 0.0 0.0 0.0 0.2 13.9 0.3 0.0 0.0 0.1 0.7 1.3 2.1 1.5 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.2 2.6 377.3 44.5 171.5 0.0 2.7 0.0 0.2 0.1 7.7 0.0 520.0 0.0 0.0 46.8 0.1 0.1 0.0 0.0 0.0 0.0 0.9 16.6 1.8 2.5 3.5 19.6 3.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 7.3 5.1 3.2 6.4 0.3 13.5 0.0 4.5 0.2 0.0 3.7 SOX5 "L-SOX5, MGC35153" ENSG00000134532 "SRY-box transcription factor 5" P35711 12 23529504-24562544 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 32.3" "Cell type enhanced" "Detected in many" "Astrocytes: 1531.5;Excitatory neurons: 615.9;Inhibitory neurons: 717.3;Oligodendrocyte precursor cells: 1437.1" "Cancer enhanced" "Detected in many" "melanoma: 3.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "memory B-cell: 1.5;naive B-cell: 1.3" "Lineage enriched" "Detected in single" 5 "B-cells: 1.5" "Cell line enhanced" "Detected in many" "AF22: 17.3;Daudi: 18.3;HDLM-2: 38.3;K-562: 17.0;WM-115: 14.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060499 Supported Nucleoplasm NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA060499: AB_2684294" "unprognostic (9.11e-4)" "unprognostic (4.64e-3)" "unprognostic (3.23e-1)" "unprognostic (6.83e-2)" "unprognostic (1.67e-1)" "unprognostic (1.10e-1)" "unprognostic (1.09e-1)" "unprognostic (1.03e-3)" "unprognostic (1.36e-1)" "unprognostic (8.40e-2)" "unprognostic (1.70e-4)" "unprognostic (6.95e-2)" "unprognostic (4.53e-4)" "unprognostic (3.12e-3)" "unprognostic (2.37e-1)" "unprognostic (9.59e-2)" "unprognostic (2.75e-2)" 5.8 1.1 6.3 1.7 9.6 0.4 1.5 0.4 10.3 6.9 0.0 1.3 0.7 5.0 1.2 1.2 3.6 3.0 2.4 6.4 7.6 1.8 11.1 2.7 3.7 2.9 5.8 7.7 1.1 0.4 0.4 8.8 5.6 2.1 1.2 3.7 3.2 3.1 0.6 6.3 1.1 2.7 3.1 1.3 1.1 32.3 6.8 0.6 2.0 1.7 3.1 1.3 0.6 5.0 0.2 0.2 17.3 0.0 9.6 5.1 0.0 0.2 0.0 0.2 0.5 3.1 0.1 18.3 0.8 0.0 0.0 0.2 9.9 0.0 0.3 38.3 2.4 3.9 0.1 8.4 6.6 0.1 0.2 2.7 0.0 0.9 0.0 2.2 0.0 0.6 17.0 0.8 0.3 0.0 7.1 0.1 5.5 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.8 0.8 0.0 0.0 6.7 4.3 0.3 3.6 0.0 0.3 2.1 0.0 1.7 0.4 0.0 1.1 4.0 0.1 14.4 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.1 6.3 9.6 0.4 10.3 6.4 7.6 2.9 5.8 5.6 3.1 6.8 5.0 4.5 6.4 11.0 1531.5 3.7 13.3 0.1 0.0 1.8 11.9 1.0 1.3 4.0 1.5 3.1 3.7 0.0 0.1 0.0 0.0 0.0 0.2 198.7 18.7 55.7 4.0 5.4 0.4 615.9 0.0 0.2 11.3 1.5 21.2 1.3 13.3 3.6 22.0 0.3 0.0 717.3 0.0 0.0 0.8 1.9 208.6 10.2 0.8 12.4 279.2 5.7 17.9 0.0 1437.1 24.4 0.0 0.0 6.8 1.2 0.1 0.4 0.6 13.8 2.6 19.7 2.8 24.7 97.0 1.4 0.5 12.1 0.3 0.7 0.2 0.2 0.2 SPHK2 ENSG00000063176 "Sphingosine kinase 2" Q9NRA0 19 48619291-48630717 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bipolar cells: 68.5;Cone photoreceptor cells: 77.2;Rod photoreceptor cells: 79.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 64.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049062 Supported Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 24: NB-4 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA049062: " "unprognostic (5.33e-2)" "unprognostic (4.11e-2)" "unprognostic (9.61e-2)" "prognostic unfavorable (5.19e-4)" "unprognostic (2.10e-1)" "unprognostic (7.19e-3)" "unprognostic (3.04e-1)" "unprognostic (4.45e-3)" "unprognostic (7.28e-2)" "unprognostic (2.80e-1)" "prognostic favorable (9.30e-4)" "unprognostic (1.25e-1)" "prognostic favorable (2.59e-5)" "unprognostic (1.18e-2)" "unprognostic (9.97e-2)" "unprognostic (4.21e-2)" "unprognostic (7.06e-2)" 9.4 10.5 18.9 6.8 20.6 3.4 9.6 23.5 29.3 9.4 9.1 16.5 22.1 12.0 2.1 9.2 11.6 3.1 7.3 25.9 19.4 23.1 31.8 8.5 5.9 36.0 30.5 15.5 8.9 7.4 16.5 2.2 37.2 13.3 3.6 3.2 7.6 4.4 7.8 4.8 18.9 2.6 21.2 11.4 14.8 24.1 30.6 5.3 16.0 3.1 3.1 10.7 7.3 26.1 8.4 22.3 8.2 15.3 8.5 3.6 16.3 8.5 6.8 9.3 11.1 39.8 10.4 15.0 5.9 5.3 5.6 6.4 7.5 6.9 1.3 17.5 19.4 16.9 11.5 13.7 13.5 11.1 17.3 6.5 3.6 6.5 4.4 4.4 5.2 20.9 11.7 12.5 4.7 8.3 27.2 64.7 11.2 6.0 10.7 23.3 6.5 10.0 4.3 5.3 29.3 23.1 8.3 12.7 8.3 4.5 7.1 6.9 8.5 13.6 7.7 10.9 17.1 24.5 31.0 16.4 7.9 12.2 12.6 11.7 6.2 2.9 4.3 7.1 4.0 5.0 3.4 4.2 5.5 8.6 4.8 4.8 2.4 5.6 6.2 5.4 3.7 3.5 18.9 20.6 23.5 29.3 25.9 19.4 36.0 30.5 37.2 21.2 30.6 26.1 3.7 6.4 7.7 8.5 13.3 3.3 5.7 5.6 4.6 68.5 6.8 6.5 1.5 12.8 6.2 11.0 77.2 6.8 13.6 20.6 1.9 6.2 11.0 6.2 6.1 6.5 16.2 2.1 9.1 5.0 6.3 5.3 15.3 6.9 4.5 14.5 6.4 19.8 8.3 45.4 11.2 11.3 4.1 12.3 7.3 18.4 16.4 6.5 3.6 6.5 11.4 20.8 33.0 6.0 11.9 6.8 16.7 12.8 7.1 6.2 44.2 18.6 4.9 79.9 6.6 6.3 5.4 18.1 6.3 7.3 2.8 4.5 12.3 8.9 17.3 4.3 SPINT1 "HAI, MANSC2" ENSG00000166145 "Serine peptidase inhibitor, Kunitz type 1" O43278 15 40844018-40858207 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 255.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1254.0;Distal enterocytes: 477.6;Proximal enterocytes: 514.5;Syncytiotrophoblasts: 1673.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 323.2;HaCaT: 377.6;hTCEpi: 264.0;RT4: 308.2;SK-BR-3: 558.8;T-47d: 267.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA006903, HPA031178" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 7400000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "HPA006903: AB_1079038, HPA031178: AB_2732463" "prognostic unfavorable (6.97e-4)" "unprognostic (1.00e-3)" "unprognostic (3.00e-3)" "unprognostic (5.03e-2)" "unprognostic (6.06e-2)" "unprognostic (3.19e-1)" "unprognostic (5.94e-2)" "unprognostic (6.04e-2)" "unprognostic (8.24e-3)" "unprognostic (1.46e-2)" "unprognostic (1.09e-3)" "unprognostic (1.01e-1)" "prognostic favorable (1.37e-7)" "unprognostic (5.37e-2)" "unprognostic (2.22e-1)" "unprognostic (6.45e-3)" "unprognostic (2.17e-2)" 2.8 0.7 0.9 16.4 1.5 1.4 34.7 5.0 1.3 42.8 6.4 108.7 159.9 13.2 78.9 255.5 33.6 38.0 1.3 0.9 2.0 79.9 3.5 47.6 6.4 2.8 3.2 2.4 69.2 132.9 31.4 144.9 2.2 52.3 89.2 0.4 162.7 31.4 0.6 148.9 138.2 4.3 1.7 6.9 88.3 1.8 3.2 9.9 34.7 0.4 45.5 57.1 90.1 2.3 124.8 1.0 0.0 0.9 0.1 0.0 323.2 2.3 3.0 4.0 2.4 195.3 202.4 0.3 141.2 0.4 3.6 377.6 30.8 181.9 2.4 1.0 10.6 5.6 3.3 10.8 2.2 21.9 93.9 0.3 264.0 3.9 16.5 3.4 14.7 12.1 2.7 1.1 0.2 96.5 0.9 16.6 37.4 207.6 17.7 12.6 0.0 24.9 179.3 308.2 79.8 3.9 9.3 558.8 15.7 56.9 267.7 16.1 0.0 0.2 2.0 1.2 0.5 1.2 24.5 0.8 0.8 16.3 1.1 0.0 19.7 14.3 0.4 15.9 0.8 8.4 3.0 1.4 32.4 6.0 1.1 0.3 25.9 5.5 18.1 4.0 0.5 7.6 0.9 1.5 5.0 1.3 0.9 2.0 2.8 3.2 2.2 1.7 3.2 2.3 0.8 57.7 14.7 0.0 7.6 76.0 96.7 220.0 55.8 0.1 96.2 63.5 0.5 105.8 207.3 134.3 0.0 1254.0 1.4 477.6 25.4 429.4 0.8 63.3 14.2 6.9 147.3 4.8 0.5 255.1 105.1 10.4 106.5 155.6 10.2 1.9 0.4 0.5 135.4 0.0 0.5 169.4 221.8 10.0 23.8 1.1 3.7 19.8 14.2 0.0 68.6 0.0 0.0 0.0 0.0 309.8 375.2 0.0 2.1 135.7 514.5 44.2 46.6 0.3 0.0 0.1 12.6 0.6 5.9 93.2 87.9 1673.8 6.6 0.1 182.7 222.3 SPTB ENSG00000070182 "Spectrin beta, erythrocytic" P11277 14 64746283-64879907 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Disease variant, Elliptocytosis, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 62.5;skeletal muscle: 123.9;tongue: 69.8" "Cell type enhanced" "Detected in some" "Erythroid cells: 81.0;Excitatory neurons: 16.0;Horizontal cells: 16.8;Inhibitory neurons: 32.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HEL: 39.2;K-562: 47.8;U-937: 14.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003394, HPA003398, CAB015169, CAB016232" Enhanced Approved Cytosol NA NA 7800000 "Cluster 80: Striated muscle - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 37: Myocytes - Muscle contraction" Cytosol "CAB015169: AB_2194363, CAB016232: AB_785785, HPA003394: AB_1080076, HPA003398: AB_1080074" "unprognostic (2.69e-1)" "unprognostic (4.72e-1)" "unprognostic (3.04e-2)" "unprognostic (2.19e-3)" "unprognostic (1.71e-1)" "unprognostic (2.33e-2)" "unprognostic (1.49e-1)" "unprognostic (1.30e-3)" "unprognostic (2.66e-1)" "unprognostic (2.28e-2)" "unprognostic (1.55e-3)" "unprognostic (2.11e-1)" "unprognostic (2.65e-1)" "unprognostic (1.39e-2)" "unprognostic (2.97e-1)" "unprognostic (3.44e-2)" "unprognostic (2.18e-2)" 2.2 1.5 5.3 0.2 11.2 62.5 0.3 28.3 11.4 0.3 27.7 0.2 0.1 0.2 5.2 2.0 0.5 0.4 22.7 10.8 4.0 1.0 0.1 0.4 0.0 28.5 5.3 0.2 2.6 11.1 5.3 6.7 28.2 1.5 0.1 1.6 2.2 1.1 123.9 0.2 0.2 0.8 8.5 0.8 0.2 0.7 9.3 0.4 0.1 69.8 0.0 0.2 0.2 4.4 0.3 1.5 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.1 0.0 0.7 0.0 0.0 0.0 0.3 0.3 2.3 6.3 0.2 0.0 0.4 3.7 39.2 0.3 0.0 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.0 0.0 1.4 47.8 0.0 0.0 0.3 0.0 0.3 0.0 0.5 2.1 0.0 0.0 0.2 0.0 0.2 6.1 2.6 0.0 0.0 0.0 0.2 0.1 0.5 0.0 0.3 6.7 0.0 0.6 1.5 7.7 0.0 0.1 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 5.3 11.2 28.3 11.4 10.8 4.0 28.5 5.3 28.2 8.5 9.3 4.4 0.1 0.0 0.0 0.7 0.0 0.8 0.7 0.6 0.0 10.3 0.5 0.1 6.3 1.5 0.7 0.0 0.0 0.1 0.5 0.0 0.0 0.3 0.4 0.4 0.9 0.4 3.0 81.0 16.0 0.2 0.3 0.8 0.0 0.9 2.5 0.2 0.0 0.0 0.2 16.8 32.1 0.3 0.0 0.0 0.4 0.4 0.3 0.3 1.8 1.9 0.0 5.0 1.0 11.1 2.1 0.3 0.0 1.2 0.1 0.7 0.0 0.2 0.0 2.6 6.6 11.6 3.8 0.1 1.1 0.5 0.4 0.1 0.6 0.4 0.1 0.6 SRD5A1 ENSG00000145545 "Steroid 5 alpha-reductase 1" P18405 5 6633427-6674386 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Differentiation, Sexual differentiation" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 29.0" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 67.2;Hepatocytes: 103.4;Ionocytes: 52.9;Squamous epithelial cells: 139.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051402 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA051402: AB_2681470" "unprognostic (1.40e-2)" "unprognostic (1.33e-2)" "unprognostic (2.30e-3)" "prognostic unfavorable (8.73e-6)" "unprognostic (9.38e-3)" "unprognostic (8.90e-2)" "unprognostic (3.78e-2)" "unprognostic (5.90e-2)" "unprognostic (3.83e-1)" "unprognostic (1.42e-1)" "unprognostic (7.70e-3)" "unprognostic (1.54e-1)" "unprognostic (1.56e-3)" "unprognostic (3.01e-1)" "unprognostic (2.24e-1)" "unprognostic (1.59e-1)" "unprognostic (5.47e-2)" 1.5 2.0 4.7 1.9 5.3 2.2 11.0 7.4 8.8 3.9 0.1 2.4 4.1 1.7 3.0 11.0 1.7 1.7 1.0 5.5 3.2 4.6 29.0 1.9 2.3 6.0 3.3 2.5 2.3 1.4 1.1 1.0 6.3 1.5 2.3 3.8 2.7 1.1 1.3 13.6 4.1 1.6 1.8 1.4 2.5 1.5 6.9 1.6 1.3 0.7 4.1 1.1 6.6 8.3 5.2 6.1 8.0 6.7 7.6 7.3 3.5 5.7 4.5 5.7 3.5 6.0 5.3 7.1 8.1 8.7 9.1 9.8 6.6 4.0 6.0 4.3 2.6 2.2 15.3 3.7 3.4 3.3 1.8 5.4 11.3 4.1 3.2 4.2 2.9 2.7 3.7 6.2 7.5 7.1 1.4 3.6 4.5 4.1 4.7 5.1 5.8 2.0 7.6 5.4 14.0 6.4 18.2 7.6 5.8 6.1 2.6 0.9 5.8 8.6 3.4 14.2 7.6 2.3 3.6 2.6 7.2 3.6 8.0 3.5 1.3 0.5 0.3 1.0 0.2 0.5 0.3 0.5 1.6 0.6 0.2 0.3 0.7 0.5 1.1 0.7 0.4 0.5 4.7 5.3 7.4 8.8 5.5 3.2 6.0 3.3 6.3 1.8 6.9 8.3 3.7 3.2 2.7 7.8 11.9 18.5 6.7 19.0 67.2 5.0 14.5 9.1 2.6 11.5 12.8 5.5 4.2 0.9 5.0 8.3 7.9 9.8 8.1 2.6 4.3 3.2 2.4 4.4 15.5 4.7 7.4 4.7 16.3 3.2 1.3 6.0 4.6 103.4 13.0 6.7 14.9 7.2 52.9 19.4 11.6 2.6 3.4 11.6 7.2 6.5 50.7 5.1 10.3 9.0 7.6 6.7 10.4 7.9 7.2 9.4 24.9 23.4 10.4 3.8 0.0 3.7 6.1 3.4 4.4 139.2 30.4 0.8 5.9 5.2 12.0 10.2 SRD5A2 ENSG00000277893 "Steroid 5 alpha-reductase 2" P31213 2 31522480-31580938 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Differentiation, Sexual differentiation" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "epididymis: 23.5;fallopian tube: 20.4;liver: 60.8;prostate: 16.8;seminal vesicle: 18.0" "Group enriched" "Detected in some" 5 "Early spermatids: 71.7;Endometrial ciliated cells: 29.6;Hepatocytes: 20.0;Late spermatids: 59.9" "Group enriched" "Detected in some" 6 "endometrial cancer: 1.1;liver cancer: 4.2;prostate cancer: 3.2" "Region enriched" "Detected in single" 11 "midbrain: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RT4: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 85: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 34: Spermatids - Unknown function" "unprognostic (6.75e-3)" "unprognostic (2.00e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-3)" "unprognostic (5.92e-3)" "unprognostic (3.37e-2)" "unprognostic (2.79e-3)" "unprognostic (6.56e-2)" "unprognostic (9.10e-2)" "unprognostic (1.39e-2)" "unprognostic (3.06e-2)" "unprognostic (9.79e-3)" "unprognostic (6.61e-6)" "unprognostic (4.37e-2)" "unprognostic (2.04e-1)" "unprognostic (3.85e-1)" "unprognostic (3.48e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 23.5 0.0 20.4 0.0 0.0 0.0 0.0 0.3 60.8 0.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.1 0.0 18.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.2 0.0 0.0 0.0 1.6 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.1 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.6 2.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.7 29.6 0.2 0.2 0.0 0.0 0.9 0.0 0.0 1.9 0.0 0.5 0.0 0.0 0.4 20.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 59.9 0.6 0.1 0.0 3.7 0.0 0.0 0.0 0.5 0.9 0.1 0.0 1.2 0.0 0.7 0.0 0.3 7.3 0.0 0.0 0.0 0.2 1.2 0.8 0.0 0.0 0.0 0.1 0.0 0.0 8.6 ST3GAL3 "MRT12, SIAT6" ENSG00000126091 "ST3 beta-galactoside alpha-2,3-sialyltransferase 3" Q11203 1 43705824-43931165 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 88.0;tongue: 82.9" "Cell type enhanced" "Detected in many" "Astrocytes: 59.7;Excitatory neurons: 94.4;Granulosa cells: 52.5;Inhibitory neurons: 120.1;Microglial cells: 57.1;Oligodendrocyte precursor cells: 66.9;Oligodendrocytes: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051102 Uncertain "Intracellular and membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA051102: AB_2681344" "unprognostic (8.42e-2)" "unprognostic (1.38e-1)" "unprognostic (1.41e-2)" "unprognostic (5.18e-2)" "unprognostic (1.22e-1)" "unprognostic (3.20e-1)" "unprognostic (9.72e-2)" "unprognostic (7.01e-2)" "unprognostic (4.39e-2)" "unprognostic (2.33e-2)" "unprognostic (1.38e-3)" "unprognostic (7.00e-2)" "unprognostic (3.68e-3)" "unprognostic (1.67e-2)" "unprognostic (1.30e-1)" "unprognostic (4.35e-1)" "unprognostic (6.60e-2)" 12.9 14.7 28.5 5.0 27.3 11.0 11.0 30.8 32.5 14.6 22.8 19.4 2.6 16.7 9.8 8.3 12.8 6.9 26.1 27.2 29.4 9.9 13.5 8.7 6.1 27.9 29.0 14.9 8.0 6.7 17.8 6.5 29.2 13.2 4.4 24.5 8.3 13.3 88.0 7.0 6.6 13.1 23.2 7.6 9.6 22.6 30.8 4.9 8.4 82.9 3.7 16.7 10.1 28.1 4.3 2.7 23.4 11.0 17.4 21.9 3.0 15.5 30.8 14.1 13.7 2.6 6.6 7.0 8.6 19.0 7.7 3.8 2.8 10.2 15.7 8.7 5.8 15.0 10.6 7.5 14.7 6.6 7.1 12.1 7.4 9.7 21.3 26.1 12.1 18.4 8.8 13.1 25.3 2.7 7.0 11.7 9.2 1.0 8.1 11.4 3.3 6.1 11.0 2.4 9.3 13.8 5.5 2.5 14.1 9.6 3.5 30.3 10.4 8.3 3.9 13.3 15.4 10.4 6.1 6.9 11.7 15.7 15.3 1.7 2.1 1.2 3.3 1.1 2.9 2.2 2.1 2.5 1.5 2.8 3.5 2.6 2.4 2.2 1.9 3.3 2.9 3.3 28.5 27.3 30.8 32.5 27.2 29.4 27.9 29.0 29.2 23.2 30.8 28.1 6.7 6.4 19.3 59.7 6.6 3.3 3.0 4.1 5.7 9.4 4.6 3.3 34.5 1.5 3.8 3.7 0.0 3.1 2.7 2.2 5.9 2.6 19.4 2.4 6.6 7.6 2.4 8.4 94.4 2.4 1.6 9.0 1.5 2.8 24.1 52.5 4.6 8.6 3.1 18.5 120.1 1.4 4.1 2.2 3.1 14.5 3.7 4.5 3.6 57.1 3.6 6.1 5.2 66.9 66.2 2.7 0.2 11.7 4.2 2.2 0.1 6.3 4.9 17.8 19.7 5.8 9.8 8.5 5.1 2.7 1.3 1.0 6.0 15.7 1.7 10.0 STPG3 "C9orf173, FLJ40246" ENSG00000197768 "Sperm-tail PG-rich repeat containing 3" Q8N7X2 9 137251261-137253483 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 42.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 3.3;RPMI-8226: 1.4;SK-BR-3: 1.2;T-47d: 2.0;U-266/70: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA044352 Uncertain Vesicles NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA044352: AB_10965328" "unprognostic (1.20e-1)" "unprognostic (5.32e-2)" "unprognostic (4.32e-3)" "unprognostic (4.72e-4)" "unprognostic (2.56e-1)" "unprognostic (1.22e-2)" "unprognostic (1.08e-2)" "unprognostic (2.77e-3)" "unprognostic (1.29e-1)" "unprognostic (3.93e-2)" "unprognostic (8.59e-4)" "unprognostic (2.09e-1)" "unprognostic (7.25e-2)" "unprognostic (2.65e-1)" "unprognostic (1.58e-1)" "unprognostic (1.29e-1)" "unprognostic (7.95e-2)" 0.9 0.5 0.0 0.4 0.0 0.3 0.2 0.2 0.1 0.3 0.0 0.1 3.9 0.2 0.2 0.1 0.4 0.2 0.2 0.0 0.1 1.1 1.5 0.1 0.4 0.1 0.1 0.0 1.3 0.0 0.7 0.2 0.1 0.3 0.0 1.5 1.3 0.0 0.0 0.6 3.0 0.0 0.1 0.4 0.5 42.5 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.4 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.9 0.5 0.1 0.0 0.0 0.4 0.0 0.0 0.0 3.3 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.6 0.4 0.0 0.8 0.0 0.1 0.0 0.2 0.2 0.0 0.0 1.4 0.0 0.0 0.4 0.2 0.1 1.2 0.0 0.2 2.0 0.0 0.0 0.3 0.6 0.1 0.0 1.2 0.7 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 STX1B "STX1B1, STX1B2" ENSG00000099365 "Syntaxin 1B" P61266 16 30989256-31010638 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter transport, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "brain: 137.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 36.8;Horizontal cells: 38.7;Inhibitory neurons: 31.1;Late spermatids: 13.8" "Cancer enriched" "Detected in some" 7 "glioma: 5.1" "Region enhanced" "Detected in many" "cerebral cortex: 137.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 9.0;hTEC/SVTERT24-B: 11.1;hTERT-RPE1: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069176, CAB079008" Supported Approved Approved "Nuclear membrane,Vesicles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 62: Horizontal cells - Visual perception" Vesicles "Nuclear membrane" "CAB079008: , HPA069176: AB_2686098" "unprognostic (1.43e-3)" "unprognostic (5.27e-2)" "unprognostic (2.40e-4)" "unprognostic (3.90e-3)" "unprognostic (3.98e-2)" "unprognostic (1.90e-2)" "unprognostic (2.21e-3)" "unprognostic (2.53e-2)" "unprognostic (1.72e-1)" "unprognostic (3.72e-3)" "unprognostic (1.73e-2)" "unprognostic (2.36e-1)" "unprognostic (1.02e-3)" "unprognostic (1.07e-1)" "unprognostic (1.58e-1)" "unprognostic (7.93e-2)" "unprognostic (1.57e-2)" 1.5 1.0 7.0 1.1 13.1 0.4 1.7 20.0 137.2 1.7 0.0 2.5 0.5 3.0 3.3 1.2 1.7 0.3 1.6 15.9 5.2 1.3 5.9 0.5 1.7 51.2 5.5 1.7 0.9 0.2 6.5 0.2 42.9 1.7 0.4 10.2 1.0 1.8 0.5 3.3 1.8 1.6 0.0 1.8 0.9 4.6 5.8 0.5 0.7 0.1 1.5 0.7 1.3 52.8 0.1 3.0 4.7 0.7 0.5 0.2 0.1 4.2 6.4 5.1 9.0 0.0 3.4 0.7 0.2 5.6 0.1 0.7 2.1 0.6 6.1 2.6 0.4 0.4 2.7 2.4 0.4 0.2 2.9 1.6 0.1 11.1 1.0 20.4 0.0 1.0 0.5 0.2 5.5 1.3 2.0 0.2 2.3 0.0 0.3 7.1 0.2 0.2 0.4 0.0 6.3 4.0 0.5 0.2 0.0 0.7 0.8 0.1 0.8 3.0 2.4 0.4 0.2 0.3 0.2 0.3 3.3 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 13.1 20.0 137.2 15.9 5.2 51.2 5.5 42.9 0.0 5.8 52.8 0.4 0.0 0.0 7.2 0.6 0.8 0.1 0.2 0.6 10.7 0.4 0.6 1.2 0.0 0.0 0.0 2.1 0.0 0.2 0.1 0.0 0.3 6.9 0.1 0.5 0.8 0.0 0.4 36.8 0.4 0.0 0.7 0.0 0.1 0.0 2.5 1.1 5.9 0.6 38.7 31.1 0.2 0.0 0.6 1.1 13.8 0.3 0.3 0.0 4.7 0.7 1.8 0.0 9.0 5.5 0.2 0.0 1.9 0.0 0.2 0.9 2.1 0.0 3.2 0.0 0.8 0.7 4.6 1.3 0.2 0.6 0.8 0.4 0.1 0.3 0.0 STYX ENSG00000198252 "Serine/threonine/tyrosine interacting protein" Q8WUJ0 14 52730166-52774989 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 117.1;Late spermatids: 92.5;Spermatocytes: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040290 Uncertain Approved Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 6: T47d - Mammary gland" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA040290: AB_10963686" "unprognostic (5.24e-2)" "unprognostic (2.48e-1)" "unprognostic (2.22e-1)" "unprognostic (9.56e-2)" "unprognostic (2.43e-1)" "unprognostic (2.16e-1)" "unprognostic (2.81e-1)" "unprognostic (2.37e-1)" "unprognostic (3.00e-3)" "unprognostic (1.91e-2)" "unprognostic (3.21e-2)" "unprognostic (2.26e-1)" "unprognostic (1.57e-3)" "unprognostic (6.89e-2)" "unprognostic (6.82e-2)" "unprognostic (2.48e-2)" "unprognostic (6.84e-3)" 9.4 3.7 3.3 8.8 4.3 5.8 7.6 4.3 4.3 5.6 2.9 6.0 5.7 6.8 4.7 9.1 4.7 5.8 8.7 2.6 3.5 5.8 26.7 5.8 14.0 4.6 4.3 6.8 5.8 4.8 2.2 9.5 4.5 6.3 6.5 3.9 5.7 5.8 11.4 8.1 5.7 6.9 3.8 9.1 6.6 10.9 3.9 9.4 5.6 12.9 12.4 7.4 4.8 5.4 14.4 7.8 10.5 12.7 17.5 24.9 20.0 16.9 12.6 12.1 12.2 11.3 10.3 17.7 14.1 16.0 10.2 11.1 13.1 13.8 21.3 16.0 5.0 9.1 8.3 15.0 14.5 14.5 11.5 17.9 16.4 16.0 16.4 10.9 22.2 15.7 11.0 16.6 16.9 19.9 16.3 9.5 12.7 16.1 15.9 13.6 14.1 10.5 15.8 16.1 2.4 7.0 17.3 11.5 11.4 14.6 28.1 14.5 20.8 21.1 13.4 23.1 10.7 6.1 8.8 10.8 6.8 9.6 18.3 7.7 4.4 3.7 5.6 6.1 7.4 6.1 9.2 7.6 4.8 3.8 10.6 8.2 2.2 4.9 5.8 3.6 10.8 5.6 3.3 4.3 4.3 4.3 2.6 3.5 4.6 4.3 4.5 3.8 3.9 5.4 15.2 6.4 9.2 6.2 18.3 16.6 10.7 10.2 9.6 5.1 14.1 8.0 23.1 8.6 11.4 5.5 6.2 13.8 19.7 7.6 13.7 12.4 117.1 9.1 10.9 16.0 4.8 15.6 7.7 18.2 32.8 11.8 11.2 8.9 20.8 5.9 16.1 54.7 15.4 5.0 7.6 6.1 8.2 21.2 20.4 92.5 9.6 20.2 3.6 10.3 27.6 8.7 15.5 6.6 15.9 14.5 7.9 11.3 16.2 19.6 8.1 12.0 14.6 6.9 26.3 8.7 19.6 73.1 25.7 16.9 19.6 21.1 25.6 5.9 8.2 13.6 SUCLG2 ENSG00000172340 "Succinate-CoA ligase GDP-forming subunit beta" Q96I99 3 67360460-67654612 "Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 278.0" "Cell type enhanced" "Detected in all" "Hepatocytes: 402.3;Proximal tubular cells: 354.4;Undifferentiated cells: 306.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046705, HPA051998" Enhanced Approved "Plasma membrane,Mitochondria" NA NA 300000 "Cluster 15: NK-cells - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "Plasma membrane" "HPA046705: AB_2679762, HPA051998: AB_2681687" "unprognostic (1.69e-1)" "unprognostic (2.31e-1)" "prognostic favorable (1.08e-4)" "unprognostic (2.12e-1)" "unprognostic (3.10e-1)" "unprognostic (5.32e-2)" "unprognostic (1.87e-2)" "unprognostic (1.69e-1)" "unprognostic (3.88e-1)" "unprognostic (3.26e-2)" "unprognostic (4.61e-3)" "unprognostic (5.59e-2)" "prognostic favorable (2.79e-10)" "unprognostic (3.08e-2)" "unprognostic (2.79e-1)" "unprognostic (1.07e-1)" "unprognostic (1.38e-1)" 66.7 44.9 16.1 36.7 17.9 18.6 48.7 17.1 19.6 42.1 22.4 169.7 136.6 32.6 32.2 50.5 39.1 48.4 85.5 14.2 17.6 147.3 278.0 34.0 39.3 19.0 17.3 39.0 47.8 34.6 10.2 28.1 19.5 49.3 146.1 7.3 46.8 42.3 154.0 26.1 132.2 40.0 17.7 44.8 110.6 10.4 18.1 24.7 49.3 130.6 35.5 39.3 24.0 18.8 43.8 37.4 36.3 44.6 59.7 102.5 44.2 51.3 74.4 58.9 65.4 41.7 95.1 55.7 16.3 72.5 38.8 22.0 28.5 70.8 75.9 23.8 19.5 50.5 31.2 65.5 76.8 67.2 33.9 77.3 60.3 46.2 105.2 73.0 63.6 41.8 39.1 49.5 129.9 30.6 25.5 21.2 34.1 199.2 23.0 17.6 56.1 83.8 100.0 66.9 7.1 24.5 81.5 92.7 68.8 24.3 71.6 42.5 55.9 58.2 38.2 64.5 61.8 33.4 52.2 39.0 85.5 51.6 70.0 17.3 36.3 13.0 30.8 44.3 37.6 45.5 44.6 39.5 24.6 42.5 68.4 53.1 1.6 68.0 37.4 9.8 45.4 48.5 16.1 17.9 17.1 19.6 14.2 17.6 19.0 17.3 19.5 17.7 18.1 18.8 40.2 35.3 50.8 66.6 48.5 37.1 44.7 38.9 21.1 2.9 54.1 29.1 172.0 84.4 51.7 80.9 8.4 55.4 31.7 223.5 244.6 85.1 3.2 49.6 43.4 40.1 58.2 17.2 6.2 80.9 44.9 47.5 90.7 46.8 30.4 31.4 45.0 402.3 56.5 5.0 5.3 212.1 40.7 68.6 49.2 5.4 41.3 36.3 42.7 90.9 35.5 29.2 36.0 72.4 60.0 59.2 164.0 47.4 30.3 41.2 222.2 354.4 58.7 4.5 32.9 41.6 50.5 1.6 6.3 55.6 49.3 38.0 48.6 78.5 306.6 50.9 SUN2 UNC84B ENSG00000100242 "Sad1 and UNC84 domain containing 2" Q9UH99 22 38734725-38794143 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 201.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001209 Supported Supported "Nuclear membrane" NA Yes "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear membrane" "HPA001209: AB_1080465" "unprognostic (9.76e-2)" "unprognostic (1.42e-1)" "unprognostic (8.32e-2)" "unprognostic (5.09e-2)" "unprognostic (1.36e-1)" "unprognostic (5.57e-2)" "unprognostic (1.94e-2)" "unprognostic (2.37e-2)" "unprognostic (3.14e-2)" "unprognostic (1.25e-3)" "unprognostic (8.15e-2)" "unprognostic (4.10e-2)" "unprognostic (1.06e-1)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (8.10e-2)" "unprognostic (2.33e-2)" 137.8 35.1 123.6 73.6 219.0 160.4 111.7 149.1 155.3 95.4 41.4 107.8 47.6 128.2 22.2 84.0 125.3 41.1 86.7 118.3 133.1 52.8 121.9 107.0 104.0 187.1 182.2 112.9 78.0 18.2 40.3 28.7 170.7 78.2 25.2 12.3 74.9 52.1 145.4 90.3 93.1 46.1 107.2 97.2 94.3 34.6 163.3 74.3 53.1 63.8 60.0 121.7 89.0 257.7 89.8 41.0 40.0 44.7 118.8 29.5 52.0 60.2 69.4 69.7 58.9 36.8 98.7 28.1 71.9 85.9 43.1 65.4 13.4 44.7 28.4 98.0 54.7 18.4 44.7 33.7 71.9 62.3 184.0 25.0 37.3 33.6 31.2 46.9 56.2 55.3 23.5 154.3 38.5 28.7 35.0 53.9 3.9 63.0 26.2 57.6 55.8 85.7 17.4 43.1 35.3 13.2 67.0 73.7 35.1 18.5 49.5 115.3 95.2 50.6 43.3 44.9 79.5 113.1 38.2 30.4 93.8 74.2 86.6 29.0 13.7 18.6 42.3 15.6 27.5 10.8 27.0 34.9 10.7 10.1 27.6 33.6 13.9 24.8 26.9 6.7 19.9 24.8 123.6 219.0 149.1 155.3 118.3 133.1 187.1 182.2 170.7 107.2 163.3 257.7 55.5 22.4 22.9 20.2 57.0 18.1 28.4 15.1 24.5 9.9 36.5 39.0 6.2 40.0 17.8 33.1 8.4 16.9 141.8 65.6 3.9 34.9 1.8 11.6 15.8 37.4 18.6 31.8 12.5 47.6 65.9 34.0 42.8 32.9 25.4 41.5 52.1 109.6 25.0 21.9 7.7 30.1 8.2 42.4 21.4 4.4 61.2 41.8 17.8 16.9 25.5 21.4 201.8 7.1 132.9 60.0 41.8 65.5 44.7 22.0 42.2 18.9 5.7 13.0 52.6 100.7 37.0 3.8 1.1 32.1 17.2 14.8 133.4 10.9 21.4 21.4 SUOX ENSG00000139531 "Sulfite oxidase" P51687 12 55997180-56006641 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 49.6;Proximal tubular cells: 35.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 72.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038208, HPA038209" Approved NA NA 44000 "Cluster 52: Eosinophils - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA038208: AB_2675892, HPA038209: AB_10672738" "unprognostic (1.72e-1)" "unprognostic (7.40e-2)" "unprognostic (2.04e-1)" "unprognostic (1.25e-2)" "unprognostic (1.86e-1)" "unprognostic (9.72e-3)" "unprognostic (1.71e-3)" "unprognostic (2.86e-3)" "unprognostic (3.27e-2)" "unprognostic (9.74e-2)" "prognostic favorable (6.28e-4)" "unprognostic (6.95e-2)" "prognostic favorable (4.77e-7)" "unprognostic (1.65e-1)" "unprognostic (1.89e-1)" "unprognostic (2.85e-2)" "prognostic favorable (8.32e-5)" 19.2 35.2 19.3 9.5 20.2 12.8 18.2 21.0 22.6 16.7 22.2 20.6 19.3 17.6 33.0 21.5 22.9 16.7 29.4 19.6 19.9 40.8 72.3 15.6 8.3 20.7 20.0 22.1 17.4 48.6 16.6 11.5 20.6 25.2 17.1 13.8 20.2 24.5 45.6 10.4 15.6 17.4 20.1 13.6 21.3 8.3 21.7 6.7 18.2 28.8 12.0 21.2 14.3 24.0 10.2 29.8 18.5 30.2 29.6 12.2 40.1 11.5 12.5 15.4 11.1 28.8 22.1 1.2 19.8 14.0 10.6 13.2 13.7 14.5 8.2 45.8 9.0 15.7 19.4 34.9 10.9 0.2 25.9 19.0 5.5 13.1 6.8 23.0 38.9 1.6 28.2 19.0 16.2 25.1 0.4 10.0 9.9 15.6 21.4 13.6 7.7 22.4 17.8 20.4 9.2 12.3 21.1 42.6 17.4 17.2 72.2 14.9 20.6 8.5 10.4 10.8 8.2 22.0 21.3 1.6 13.7 10.2 12.7 11.1 12.6 29.6 0.2 18.7 0.1 2.5 1.2 0.0 16.1 0.3 0.9 0.2 5.1 16.5 16.2 0.5 7.9 11.8 19.3 20.2 21.0 22.6 19.6 19.9 20.7 20.0 20.6 20.1 21.7 24.0 4.5 9.6 10.9 10.7 1.1 1.3 3.8 6.7 6.2 5.1 9.1 6.1 21.7 11.5 12.8 14.7 6.2 29.7 0.9 7.7 17.6 5.6 0.7 7.7 6.7 7.1 6.0 6.5 4.1 6.3 19.1 6.4 6.6 12.4 4.5 6.6 8.9 49.6 10.5 10.1 4.4 6.0 4.1 8.9 4.0 0.9 4.4 4.3 1.8 5.6 10.0 8.5 2.1 5.5 6.2 5.3 7.4 9.1 3.2 3.1 7.9 35.8 6.1 8.4 6.6 8.4 5.4 2.4 1.4 6.8 2.3 30.8 1.6 6.7 7.7 3.0 SVEP1 "bA427L11.3, C9orf13, FLJ13529, POLYDOM" ENSG00000165124 "Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1" Q4LDE5 9 110365248-110579880 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 38.6;placenta: 61.7" "Cell type enhanced" "Detected in many" "Fibroblasts: 92.8;Inhibitory neurons: 50.3;Leydig cells: 42.0;Oligodendrocytes: 140.5;Syncytiotrophoblasts: 67.3;Theca cells: 34.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "ASC diff: 147.1;ASC TERT1: 84.7;BJ hTERT+: 62.3;HHSteC: 53.8;HSkMC: 66.7" "Region enhanced" "Detected in some" "cerebellum: 2.8" "Region enriched" "Detected in all" 5 "cerebellum: 20.8" "HPA020610, HPA021520" Enhanced "Intracellular and membrane" NA NA 160000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA020610: AB_2197021, HPA021520: AB_1855533" "unprognostic (4.47e-2)" "unprognostic (6.01e-2)" "unprognostic (1.62e-2)" "unprognostic (1.04e-2)" "unprognostic (2.31e-1)" "unprognostic (2.62e-2)" "unprognostic (9.13e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-2)" "unprognostic (3.31e-3)" "unprognostic (2.25e-1)" "unprognostic (1.51e-1)" "unprognostic (4.11e-2)" "prognostic unfavorable (8.33e-4)" "unprognostic (9.84e-2)" "unprognostic (2.21e-1)" "unprognostic (1.55e-3)" 38.6 4.2 1.5 2.5 8.6 0.0 23.2 8.9 2.8 10.6 0.9 9.7 1.2 8.6 5.6 3.5 12.4 6.2 6.5 1.1 3.4 3.9 2.9 19.7 3.8 2.7 5.3 3.9 4.7 5.3 0.8 61.7 3.3 1.7 5.1 0.0 4.1 2.1 4.4 11.3 8.7 9.5 1.0 5.2 7.7 1.0 4.3 1.8 7.4 5.5 2.4 9.7 12.1 6.1 0.0 0.1 1.2 0.0 147.1 84.7 0.0 16.3 62.3 1.2 1.9 1.5 0.0 0.0 0.0 3.9 0.1 0.0 0.0 12.2 1.0 0.0 0.3 0.1 1.4 0.0 53.8 0.0 2.9 66.7 0.0 12.1 3.2 1.4 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.2 7.5 2.0 0.0 10.6 0.0 0.0 0.0 2.3 0.0 1.0 0.0 1.3 2.5 0.0 7.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 8.6 8.9 2.8 1.1 3.4 2.7 5.3 3.3 1.0 4.3 6.1 7.4 0.0 0.5 2.9 0.1 5.7 0.6 0.5 1.2 0.5 0.4 0.9 1.8 5.7 0.1 0.0 0.0 12.2 0.3 0.0 0.0 0.9 0.3 0.5 13.8 2.0 0.0 0.0 16.9 0.2 1.6 92.8 4.1 0.3 0.0 0.0 2.2 0.0 3.0 0.0 50.3 0.0 0.0 0.0 8.2 0.6 42.0 0.6 7.2 13.1 0.0 0.0 0.0 3.0 140.5 0.0 1.2 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.0 3.5 7.8 0.4 1.5 0.4 3.3 67.3 1.2 34.1 0.2 0.2 SVOP DKFZp761H039 ENSG00000166111 "SV2 related protein" Q8N4V2 12 108907741-109021068 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 14.3;pituitary gland: 7.4;retina: 13.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 41.7;Early spermatids: 65.4;Excitatory neurons: 70.3;Inhibitory neurons: 75.8;Late spermatids: 121.5" "Group enriched" "Detected in some" 9 "glioma: 0.6;pancreatic cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "Karpas-707: 2.8;RPMI-8226: 3.0;SCLC-21H: 1.5;SH-SY5Y: 1.3;U-266/84: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016573 Uncertain NA NA "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA016573: AB_2197027" "unprognostic (6.88e-2)" "unprognostic (1.10e-1)" "unprognostic (2.09e-1)" "unprognostic (6.51e-3)" "unprognostic (2.18e-2)" "unprognostic (3.79e-1)" "unprognostic (1.84e-2)" "unprognostic (1.25e-1)" "unprognostic (3.38e-2)" "unprognostic (4.29e-3)" "unprognostic (3.07e-1)" "unprognostic (4.28e-3)" "unprognostic (3.94e-2)" "unprognostic (2.26e-2)" "unprognostic (6.17e-2)" 0.0 1.5 11.2 0.1 12.4 0.1 0.0 2.2 14.3 0.0 0.0 0.3 0.5 0.0 0.1 0.0 0.0 0.0 1.0 11.3 9.5 0.1 0.2 0.0 0.0 2.9 2.1 0.0 0.7 0.0 7.4 0.0 3.7 0.0 0.1 13.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.0 0.7 0.5 6.4 0.0 0.0 0.1 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 1.5 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 11.2 12.4 2.2 14.3 11.3 9.5 2.9 2.1 3.7 0.4 6.4 6.0 0.2 12.8 9.6 2.6 0.1 0.0 0.7 0.0 0.0 19.7 0.1 0.0 1.3 0.0 5.0 1.8 41.7 1.3 0.0 0.1 0.0 0.1 65.4 0.1 0.1 1.0 16.8 0.0 70.3 0.0 0.3 0.6 0.0 0.2 2.5 0.1 1.1 0.1 0.1 11.8 75.8 0.0 0.0 0.0 0.0 121.5 0.3 1.0 0.0 1.0 0.1 2.1 0.0 4.0 2.8 0.1 0.0 0.7 0.0 0.3 0.0 0.1 0.0 21.9 0.0 1.5 0.7 0.7 0.9 0.0 0.0 0.8 0.5 0.1 0.0 0.4 SYNGR1 ENSG00000100321 "Synaptogyrin 1" O43759 22 39349925-39385575 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "melanoma: 19.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 7 "dendritic cells: 44.7;monocytes: 38.9;T-cells: 30.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029673, CAB034277" Enhanced Supported Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 6: T47d - Mammary gland" "Cluster 33: Fibroblasts - ECM organization" Cytosol "CAB034277: AB_2255766, HPA029673: AB_10670430" "unprognostic (2.68e-3)" "unprognostic (1.84e-3)" "unprognostic (5.90e-2)" "unprognostic (8.51e-2)" "unprognostic (3.74e-1)" "unprognostic (5.98e-3)" "unprognostic (7.39e-2)" "unprognostic (4.95e-2)" "unprognostic (1.83e-2)" "unprognostic (1.06e-2)" "prognostic favorable (2.41e-4)" "unprognostic (1.16e-1)" "prognostic favorable (4.98e-7)" "unprognostic (1.32e-3)" "unprognostic (1.20e-1)" "unprognostic (2.02e-2)" "unprognostic (1.04e-1)" 9.9 24.6 73.2 4.9 84.9 92.9 14.7 64.7 121.8 36.2 25.3 26.7 5.9 22.1 11.6 37.3 23.5 11.3 57.0 84.7 37.5 26.2 5.3 8.6 7.5 35.1 37.9 72.7 28.0 29.8 15.2 6.5 36.5 29.6 4.3 73.0 45.1 18.0 29.0 51.8 11.8 13.2 6.3 10.6 16.6 19.8 58.4 3.5 11.6 26.4 9.9 25.6 34.9 67.1 5.4 9.6 17.3 31.1 1.7 4.4 7.5 23.2 40.8 29.2 26.9 2.1 0.6 0.2 5.3 6.1 3.3 7.6 11.8 0.5 8.8 0.1 36.6 0.4 0.8 1.0 4.9 1.6 10.5 6.7 1.8 7.9 0.0 20.7 1.4 6.8 11.0 0.7 4.6 12.5 4.8 4.5 3.6 4.8 18.7 14.0 0.0 1.5 0.9 15.0 27.1 5.5 6.1 25.1 23.7 7.1 36.9 27.3 0.5 0.0 19.6 0.3 0.1 6.4 0.2 15.2 0.8 30.2 31.6 0.6 38.9 0.8 30.8 11.8 1.7 5.8 1.1 9.1 44.7 4.2 1.3 15.3 1.7 5.1 0.6 33.1 0.2 18.0 73.2 84.9 64.7 121.8 84.7 37.5 35.1 37.9 36.5 6.3 58.4 67.1 8.9 9.6 1.1 28.4 21.0 30.3 73.6 33.8 39.3 112.9 61.4 73.0 73.6 75.8 31.4 66.2 27.1 25.0 52.5 0.1 15.6 57.2 40.0 14.3 24.4 9.5 0.0 92.9 57.1 12.3 14.4 44.6 1.5 18.5 2.5 49.0 12.1 5.9 14.2 47.1 47.1 0.3 12.2 20.0 13.8 87.9 133.3 11.7 140.5 20.6 10.1 46.8 91.6 39.7 18.7 21.7 1.1 119.2 23.2 36.4 0.1 9.3 7.5 38.6 19.7 46.8 30.6 62.8 14.7 57.1 37.4 13.1 21.2 131.6 0.4 80.2 SYT1 "P65, SVP65, SYT" ENSG00000067715 "Synaptotagmin 1" P21579 12 78863993-79452008 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Differentiation "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "brain: 403.3;retina: 197.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 1287.6;Cone photoreceptor cells: 894.5;Excitatory neurons: 3753.2;Inhibitory neurons: 2910.4;Rod photoreceptor cells: 905.8" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 10 "amygdala: 113.1;basal ganglia: 153.7;cerebral cortex: 403.3;hippocampal formation: 134.2;white matter: 146.0" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.0;naive B-cell: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTERT-HME1: 39.4;hTERT-RPE1: 37.1;LHCN-M2: 31.9;SH-SY5Y: 30.9;WM-115: 29.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008394, HPA064788" Enhanced Supported NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA008394: AB_1857696, HPA064788: AB_2685351" "unprognostic (1.02e-3)" "unprognostic (2.55e-1)" "unprognostic (4.21e-3)" "unprognostic (3.77e-2)" "unprognostic (3.16e-2)" "unprognostic (3.68e-5)" "unprognostic (2.78e-2)" "unprognostic (1.83e-2)" "unprognostic (7.65e-2)" "unprognostic (1.83e-1)" "unprognostic (1.11e-1)" "unprognostic (6.14e-3)" "unprognostic (3.05e-8)" "unprognostic (2.89e-2)" "unprognostic (8.26e-2)" "unprognostic (1.43e-1)" "unprognostic (1.53e-2)" 0.5 21.7 113.1 2.2 153.7 0.6 0.7 19.7 403.3 1.4 0.0 4.4 1.5 9.9 0.7 0.7 0.8 1.3 0.2 134.2 2.0 1.9 1.9 0.9 0.3 0.0 0.0 5.2 0.3 0.0 6.4 2.6 3.0 6.6 2.8 197.7 0.2 5.5 0.2 0.2 3.4 25.2 0.0 2.6 1.3 0.7 12.5 0.5 0.3 0.5 0.3 1.6 2.5 146.0 0.0 19.2 14.2 0.0 1.4 4.0 0.0 1.4 1.7 1.0 1.1 1.0 0.5 0.0 2.8 0.2 5.0 0.6 0.3 2.2 1.6 0.3 0.7 1.0 0.5 0.0 3.6 0.0 0.3 1.1 1.4 5.2 39.4 37.1 13.6 0.7 0.7 2.2 31.9 3.1 1.8 0.0 10.3 2.1 5.3 0.0 14.3 0.0 0.0 5.5 18.8 30.9 0.0 2.4 0.3 9.5 6.8 0.0 5.4 2.0 0.7 0.0 6.2 3.4 8.0 0.1 4.5 0.0 29.0 0.0 0.7 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 113.1 153.7 19.7 403.3 134.2 2.0 0.0 0.0 3.0 0.0 12.5 146.0 2.2 0.0 0.6 124.7 9.0 0.9 0.1 0.0 0.0 1287.6 0.2 3.4 0.6 0.0 1.3 0.0 894.5 5.6 0.1 0.1 0.0 0.0 1.4 0.6 20.2 10.4 96.9 1.3 3753.2 0.2 2.2 5.9 0.0 0.7 0.0 0.7 1.8 0.1 13.9 62.2 2910.4 0.1 0.0 4.7 7.2 2.9 69.3 1.6 1.8 137.7 0.0 337.7 0.0 126.2 105.1 0.1 7.6 4.5 8.5 11.5 0.1 0.1 0.0 905.8 0.0 0.0 6.7 1.5 5.7 0.2 0.6 5.9 0.4 1.8 0.1 0.3 SYT13 KIAA1427 ENSG00000019505 "Synaptotagmin 13" Q7L8C5 11 45240302-45286341 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.1;gallbladder: 20.8;pituitary gland: 16.8" "Cell type enriched" "Detected in many" 7 "Enteroendocrine cells: 336.8" "Group enriched" "Detected in many" 5 "breast cancer: 13.5;colorectal cancer: 7.4;pancreatic cancer: 19.9;renal cancer: 16.9;stomach cancer: 11.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 19.1;NTERA-2: 8.8;RPTEC TERT1: 56.8;SCLC-21H: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046224, HPA056602" Uncertain Supported Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "HPA046224: AB_10961288, HPA056602: AB_2683185" "unprognostic (4.96e-2)" "unprognostic (1.06e-2)" "unprognostic (9.92e-2)" "prognostic unfavorable (7.79e-5)" "unprognostic (1.00e-2)" "unprognostic (4.17e-2)" "unprognostic (3.75e-2)" "unprognostic (9.83e-3)" "unprognostic (2.19e-1)" "unprognostic (7.58e-2)" "unprognostic (1.21e-1)" "unprognostic (2.47e-1)" "unprognostic (5.66e-3)" "unprognostic (2.94e-2)" "unprognostic (1.76e-1)" "unprognostic (8.70e-2)" "unprognostic (5.13e-2)" 0.1 4.7 7.0 1.5 12.7 0.0 0.2 1.7 30.1 0.0 0.0 12.2 12.5 0.2 0.0 0.0 0.2 20.8 5.2 18.0 11.5 8.9 0.3 0.5 0.0 5.7 1.2 0.0 7.1 0.4 16.8 0.0 5.4 1.8 12.6 11.3 1.9 0.0 0.1 0.2 12.8 0.8 0.0 0.1 11.0 1.7 9.0 0.3 1.6 0.1 0.0 0.0 0.0 5.2 0.0 19.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.2 0.0 1.1 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 8.8 0.0 0.2 0.0 0.0 0.0 56.8 0.0 15.0 0.7 0.0 0.0 0.1 0.7 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 12.7 1.7 30.1 18.0 11.5 5.7 1.2 5.4 0.0 9.0 5.2 0.0 0.0 0.0 4.6 0.1 0.0 0.2 0.0 0.0 3.3 0.1 0.3 15.3 17.2 0.0 3.7 25.0 0.0 0.0 10.2 5.9 1.2 3.1 0.4 0.2 0.1 336.8 0.0 41.6 0.6 0.0 1.7 3.6 2.0 0.0 2.5 0.0 0.0 0.0 1.7 43.8 37.3 4.1 0.0 0.0 9.7 0.3 0.0 0.0 5.6 0.0 0.7 0.0 1.5 3.5 8.2 14.3 0.0 0.0 2.3 13.9 0.5 0.0 2.7 0.0 0.0 0.2 2.0 0.2 0.0 0.0 0.0 0.0 0.0 32.8 0.2 SYTL2 "CHR11SYT, exophilin-4, FLJ20163, FLJ21219, KIAA1597, MGC102768, PPP1R151, SGA72M, SLP2" ENSG00000137501 "Synaptotagmin like 2" Q9HCH5 11 85694224-85811159 "Plasma proteins, Predicted intracellular proteins, Transporters" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 74.2;stomach 1: 127.7" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 382.2;granulocytes: 130.8;Intestinal goblet cells: 185.9;Respiratory ciliated cells: 138.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 14.0;MAIT T-cell: 23.7" "Lineage enriched" "Detected in many" 5 "T-cells: 23.7" "Cell line enhanced" "Detected in many" "MCF7: 91.1;OE19: 148.1;RH-30: 175.8;RPTEC TERT1: 124.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039651 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Golgi apparatus" "Plasma membrane" "HPA039651: AB_10795153" "unprognostic (8.07e-3)" "unprognostic (6.72e-3)" "prognostic favorable (2.67e-4)" "unprognostic (9.34e-4)" "unprognostic (6.60e-3)" "unprognostic (2.19e-4)" "unprognostic (2.24e-2)" "unprognostic (5.37e-2)" "unprognostic (5.56e-2)" "unprognostic (5.45e-2)" "unprognostic (1.92e-2)" "unprognostic (2.97e-2)" "unprognostic (2.85e-2)" "unprognostic (4.03e-1)" "unprognostic (1.87e-2)" "unprognostic (9.72e-2)" "prognostic favorable (9.07e-4)" 16.7 9.6 19.3 12.9 24.6 3.3 16.0 8.7 35.7 10.7 11.9 51.7 21.6 9.1 16.3 17.0 7.6 27.8 8.4 29.0 25.1 20.2 6.9 14.8 11.1 26.4 14.0 4.8 2.7 6.4 6.1 18.2 17.9 13.6 74.2 13.3 8.9 9.8 5.1 6.8 25.0 10.2 15.6 10.4 127.7 5.1 13.8 7.1 4.7 2.7 6.8 50.9 7.4 29.1 3.5 8.0 12.2 1.0 2.8 15.4 0.2 30.3 39.4 26.3 59.2 34.7 4.5 0.7 11.1 21.3 38.0 22.3 0.8 2.7 34.5 2.4 0.2 0.0 0.2 0.3 1.8 2.7 0.5 19.6 3.8 56.8 0.8 6.2 0.2 1.0 0.4 0.4 33.6 91.1 0.1 0.9 20.6 148.1 13.6 1.3 175.8 0.1 124.2 46.8 0.3 0.6 6.7 5.4 3.0 10.2 0.6 0.5 0.1 40.8 15.6 25.9 1.5 0.2 0.0 16.1 41.9 0.5 25.7 0.0 0.0 0.0 14.0 0.0 23.7 0.0 2.8 8.4 0.0 0.1 2.3 4.1 0.0 4.6 0.1 1.0 1.1 2.6 19.3 24.6 8.7 35.7 29.0 25.1 26.4 14.0 17.9 15.6 13.8 29.1 7.5 22.4 32.5 15.3 3.0 3.6 11.7 15.8 1.8 10.4 45.4 14.0 2.3 8.6 62.1 68.0 8.4 0.7 45.6 115.2 0.0 9.1 1.2 8.0 2.2 6.4 19.2 4.0 103.9 16.9 0.4 11.5 382.2 2.3 130.8 0.8 5.0 0.5 0.5 1.7 23.2 185.9 2.0 5.9 5.0 0.9 1.8 4.6 10.6 20.6 1.6 14.0 63.8 35.7 91.9 16.5 40.6 30.1 31.6 30.7 16.3 8.6 138.4 8.1 32.9 42.1 59.8 3.6 2.6 2.2 5.7 0.4 50.1 2.3 36.7 60.9 TACSTD2 "EGP-1, GA733-1, M1S1, TROP2" ENSG00000184292 "Tumor associated calcium signal transducer 2" P09758 1 58575433-58577252 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Tumor antigen" "Amyloidosis, Corneal dystrophy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 989.6;salivary gland: 468.5;skin 1: 438.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 6559.0;Basal respiratory cells: 3141.0;Club cells: 2499.0;Prostatic glandular cells: 3724.1;Squamous epithelial cells: 2716.6;Urothelial cells: 8102.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 15.0" "Group enriched" "Detected in many" 79 "dendritic cells: 4.3;granulocytes: 15.0;monocytes: 4.2" "Cell line enhanced" "Detected in many" "A-431: 766.6;CAPAN-2: 1005.9;HaCaT: 1010.0;RT4: 355.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA043104, HPA055067, CAB072852" Enhanced Supported "Nucleoli,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "Nucleoli, Vesicles" "CAB072852: , HPA043104: AB_10960710, HPA055067: AB_2682687" "unprognostic (1.80e-2)" "unprognostic (3.08e-1)" "unprognostic (3.67e-3)" "unprognostic (1.22e-1)" "unprognostic (5.70e-2)" "unprognostic (2.15e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (1.99e-1)" "unprognostic (1.03e-2)" "unprognostic (1.71e-2)" "unprognostic (7.91e-2)" "prognostic favorable (3.99e-4)" "unprognostic (7.10e-2)" "unprognostic (2.55e-1)" "unprognostic (6.91e-3)" "unprognostic (2.50e-1)" 4.8 1.2 0.2 1.3 0.4 13.5 135.8 0.2 0.4 218.6 1.9 1.1 0.7 19.1 25.3 989.6 27.7 13.0 0.8 0.3 0.3 137.9 4.0 71.2 1.0 0.2 0.3 1.5 81.1 3.5 2.4 17.7 0.2 126.8 0.9 0.0 468.5 97.1 1.9 438.8 1.2 2.0 0.2 1.0 65.7 0.5 0.3 9.2 5.0 0.3 180.0 234.6 375.0 0.6 766.6 0.1 0.0 1.5 0.0 0.0 280.1 0.2 0.0 0.0 0.1 0.7 1005.9 0.1 94.7 64.2 0.1 1010.0 0.0 186.5 0.0 0.7 0.0 0.2 19.7 0.3 0.3 0.1 0.8 0.2 274.5 0.4 11.3 0.0 42.5 0.0 0.2 1.3 0.0 166.3 0.6 1.1 0.5 167.0 1.4 0.2 0.1 0.6 137.0 355.3 0.2 0.3 32.4 264.9 1.0 3.2 173.6 1.5 45.4 1.0 1.7 0.8 1.7 0.4 0.9 0.7 1.0 0.3 0.7 0.0 4.2 15.0 0.0 0.1 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 1.8 0.2 0.4 0.2 0.4 0.3 0.3 0.2 0.3 0.2 0.2 0.3 0.6 9.0 346.1 109.2 0.0 3.1 1490.5 6559.0 3141.0 1226.5 0.0 789.8 445.6 0.4 338.8 2499.0 1278.2 0.0 107.1 9.1 2.8 43.0 2165.2 0.0 482.3 48.6 60.4 0.0 0.0 0.1 1263.4 8.1 36.3 143.2 608.7 8.8 0.2 1.4 0.5 8.8 0.0 0.0 8.5 1143.4 0.8 203.4 0.0 0.0 34.8 113.8 0.0 31.3 0.0 0.0 0.0 0.6 1778.0 3.6 0.0 1.4 3724.1 0.2 3.4 1080.4 0.0 0.0 1.3 142.4 0.4 1.1 2716.6 1531.8 78.4 32.8 0.0 1.5 8102.8 TBC1D10C "Carabin, EPI64C, FLJ00332" ENSG00000175463 "TBC1 domain family member 10C" Q8IV04 11 67403915-67410089 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 40.4;intestine: 25.6;lymphoid tissue: 58.6" "Group enriched" "Detected in many" 4 "B-cells: 109.6;dendritic cells: 144.4;NK-cells: 284.2;T-cells: 147.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 19.0;JURKAT: 27.3;MOLT-4: 47.1;NB-4: 64.7;U-937: 24.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA069743 Enhanced Approved "Nuclear bodies" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear bodies" "HPA069743: AB_2686186" "prognostic favorable (3.83e-4)" "prognostic favorable (4.20e-4)" "unprognostic (9.23e-2)" "unprognostic (3.84e-2)" "unprognostic (1.28e-3)" "prognostic favorable (1.86e-5)" "unprognostic (6.22e-3)" "unprognostic (1.17e-2)" "unprognostic (3.65e-2)" "unprognostic (3.55e-2)" "unprognostic (3.28e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (4.35e-7)" "unprognostic (1.52e-1)" "unprognostic (3.88e-2)" "unprognostic (7.18e-2)" "unprognostic (3.81e-2)" 2.3 0.7 0.7 25.8 1.2 40.4 1.1 0.4 1.2 1.4 0.8 4.1 5.5 0.9 0.1 2.3 1.9 3.2 0.9 0.6 0.6 2.5 2.6 8.9 56.7 0.9 0.5 0.5 0.8 0.2 0.5 0.8 0.6 1.9 1.5 0.0 3.8 0.7 0.9 1.4 25.6 0.5 0.5 58.6 7.6 0.5 0.7 46.0 7.6 0.6 21.8 3.2 1.7 1.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 8.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 11.7 0.1 1.2 0.0 6.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 27.3 0.1 0.0 0.0 0.3 47.1 64.7 0.0 0.0 0.0 6.6 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 4.5 0.0 0.0 0.1 0.2 0.0 0.4 0.5 12.2 0.0 24.6 0.0 191.0 46.0 270.4 237.7 120.4 169.7 177.3 201.5 208.3 65.6 184.2 206.7 192.0 237.6 148.0 167.0 55.8 286.6 261.6 0.7 1.2 0.4 1.2 0.6 0.6 0.9 0.5 0.6 0.5 0.7 1.1 2.5 6.4 19.5 0.0 109.6 1.1 0.1 0.1 0.6 1.0 1.4 1.9 1.5 2.8 2.5 0.0 0.0 0.2 144.4 0.2 0.0 0.2 0.2 2.4 0.4 1.9 1.2 12.6 0.2 0.0 0.3 2.0 2.0 1.1 23.4 0.1 5.0 1.4 23.7 0.0 0.1 0.0 0.0 16.0 6.9 0.6 0.0 23.1 3.6 1.0 24.5 0.3 284.2 0.0 0.5 0.0 0.0 0.0 40.2 0.1 0.1 1.1 1.3 0.5 0.0 1.3 1.1 0.1 0.2 0.0 1.0 0.4 147.7 0.1 0.1 0.1 TBX10 "TBX13, TBX7" ENSG00000167800 "T-box transcription factor 10" O75333 11 67631303-67639560 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 14 "intestine: 9.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 14.8;Intestinal goblet cells: 103.8;Paneth cells: 20.4;Proximal enterocytes: 42.7" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 2.4;NTERA-2: 5.3;RPMI-8226: 3.6;SK-BR-3: 12.5;U-2 OS: 2.5" "Low region specificity" "Detected in single" "HPA047881, HPA076197" Uncertain Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm Cytosol "HPA047881: AB_2680199, HPA076197: " "unprognostic (4.66e-2)" "unprognostic (2.96e-2)" "unprognostic (7.71e-3)" "unprognostic (1.79e-1)" "unprognostic (2.37e-1)" "unprognostic (1.83e-4)" "unprognostic (3.12e-1)" "unprognostic (3.29e-2)" "unprognostic (5.10e-2)" "unprognostic (1.83e-1)" "unprognostic (4.90e-1)" "unprognostic (1.17e-10)" "unprognostic (6.77e-2)" "unprognostic (1.68e-1)" "unprognostic (2.95e-1)" "unprognostic (2.75e-1)" 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.2 0.0 0.0 8.4 5.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 8.0 0.0 0.4 0.0 0.0 0.0 9.7 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 5.3 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.1 0.0 12.5 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.9 0.0 0.0 0.0 103.8 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 20.4 0.0 0.0 0.2 42.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.9 0.1 TBX2 ENSG00000121068 "T-box transcription factor 2" Q13207 17 61399843-61409466 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 62.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 134.1;Collecting duct cells: 95.6;Muller glia cells: 139.8;Sertoli cells: 170.9;Smooth muscle cells: 104.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 129.3;MCF7: 78.5;SH-SY5Y: 65.4;SK-MEL-30: 49.3;WM-115: 43.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA008586, CAB013636" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "CAB013636: , HPA008586: AB_1080222" "unprognostic (6.18e-2)" "unprognostic (8.51e-2)" "unprognostic (4.50e-1)" "unprognostic (2.09e-1)" "unprognostic (1.36e-1)" "unprognostic (8.45e-2)" "unprognostic (3.27e-1)" "unprognostic (1.82e-1)" "unprognostic (3.49e-2)" "unprognostic (9.29e-2)" "unprognostic (2.10e-2)" "unprognostic (2.10e-1)" "unprognostic (2.32e-3)" "unprognostic (1.97e-1)" "unprognostic (1.37e-1)" "unprognostic (1.45e-1)" "unprognostic (6.34e-3)" 21.1 3.7 2.9 2.6 3.4 0.0 16.1 2.7 4.6 14.5 1.7 9.8 4.9 22.0 14.1 7.1 15.7 4.5 19.9 2.2 3.2 31.7 4.9 62.8 1.0 3.8 4.1 10.2 3.6 2.1 6.2 24.7 3.8 16.3 1.8 6.3 4.2 27.5 8.1 5.6 11.4 4.6 2.3 13.7 11.5 5.4 3.9 0.8 15.9 5.8 0.5 31.2 13.0 2.2 0.5 1.9 0.0 129.3 4.2 4.4 15.6 22.4 21.2 1.0 0.2 3.6 0.4 0.0 1.6 3.3 2.5 0.0 2.4 0.0 0.4 0.0 8.8 2.2 0.0 6.4 14.0 0.4 2.1 8.0 0.2 23.4 1.3 0.3 0.0 0.0 0.5 0.0 1.4 78.5 0.0 0.4 0.1 0.0 9.4 0.0 5.3 0.2 0.0 31.0 0.3 65.4 0.0 0.0 49.3 0.2 1.6 2.5 0.0 2.9 0.0 7.3 4.7 0.1 0.3 0.0 17.6 0.0 43.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 3.4 2.7 4.6 2.2 3.2 3.8 4.1 3.8 2.3 3.9 2.2 12.7 0.0 0.6 2.3 0.1 0.6 0.3 0.0 0.0 134.1 0.4 1.1 11.1 0.0 0.0 95.6 22.9 0.4 0.5 0.0 1.9 0.1 0.8 1.4 45.7 12.2 0.0 0.0 0.1 0.0 0.4 13.7 0.5 1.6 0.0 0.1 12.1 0.0 0.9 1.7 0.0 0.0 0.0 1.0 1.8 1.1 39.4 1.1 1.8 5.6 0.0 139.8 0.0 0.0 0.1 0.0 0.0 47.4 0.0 0.5 0.0 25.1 0.0 13.4 170.9 0.8 104.0 0.4 0.7 0.1 0.3 0.3 0.9 1.1 0.0 0.2 THNSL1 "FLJ22002, TSH1" ENSG00000185875 "Threonine synthase like 1" Q8IYQ7 10 25016612-25026664 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 21.4" "Cell type enhanced" "Detected in many" "Distal tubular cells: 15.6;Early spermatids: 29.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 32.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037585 Uncertain Approved "Nuclear bodies,Mitochondria,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear bodies, Cytosol" Mitochondria "HPA037585: AB_10696940" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (2.31e-1)" "unprognostic (4.31e-2)" "unprognostic (5.26e-2)" "unprognostic (6.11e-2)" "unprognostic (8.91e-2)" "unprognostic (1.05e-1)" "unprognostic (2.80e-1)" "unprognostic (9.75e-2)" "unprognostic (2.63e-2)" "unprognostic (1.52e-1)" "unprognostic (1.71e-3)" "unprognostic (2.08e-1)" "unprognostic (3.21e-2)" "unprognostic (9.84e-3)" "unprognostic (3.06e-2)" 1.7 6.0 4.0 1.8 4.2 0.6 3.6 3.2 4.5 4.1 2.9 2.7 2.6 3.6 4.9 1.9 5.6 2.0 3.7 4.1 4.2 9.7 21.4 1.5 2.8 3.9 3.5 7.3 3.0 5.3 3.7 1.7 4.2 2.9 3.0 4.1 3.4 2.6 4.6 2.2 2.4 2.2 3.9 2.2 2.7 5.9 4.1 3.3 8.3 5.9 2.7 1.8 1.5 4.3 7.1 8.1 5.0 10.0 5.0 6.2 1.3 3.4 1.3 3.7 2.4 5.3 8.8 32.7 10.6 1.6 4.0 3.8 7.2 6.4 3.8 4.5 3.9 12.0 2.2 3.4 5.6 0.0 2.0 3.9 11.6 2.7 5.7 6.4 2.5 13.3 10.4 3.8 8.0 11.1 6.6 2.3 9.2 12.3 3.9 3.5 1.3 14.2 10.6 1.6 8.3 4.7 6.8 6.0 12.3 2.6 6.0 0.6 2.5 4.4 3.9 5.9 3.2 2.7 3.8 0.0 7.3 6.6 3.5 0.1 0.4 0.0 2.9 0.5 5.1 5.0 4.1 3.8 2.2 3.8 9.5 6.3 0.6 10.8 0.7 3.7 2.0 3.1 4.0 4.2 3.2 4.5 4.1 4.2 3.9 3.5 4.2 3.9 4.1 4.3 1.3 3.2 3.2 2.6 3.4 0.6 3.1 5.6 2.8 4.2 2.1 2.9 8.5 1.5 6.1 3.7 0.0 6.1 0.8 0.6 15.6 3.3 29.9 5.1 3.9 1.8 1.2 2.5 4.0 1.3 3.9 2.7 1.5 2.5 0.0 7.8 2.2 9.8 2.1 3.3 5.1 1.8 2.0 0.9 0.8 5.5 2.1 0.6 0.0 4.7 1.5 6.8 0.0 2.0 5.4 1.1 1.0 1.5 0.9 1.8 2.3 11.0 8.7 4.5 0.0 4.3 1.9 8.2 13.6 2.6 1.0 1.0 2.8 11.8 3.5 1.1 TLCD4 "FLJ31842, TMEM56" ENSG00000152078 "TLC domain containing 4" Q96MV1 1 95117355-95197607 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 130.0" "Cell type enriched" "Detected in some" 9 "Cardiomyocytes: 77.9" "Cancer enhanced" "Detected in many" "liver cancer: 13.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 22.4;RH-30: 35.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046762 Approved "Nuclear speckles" No No "Cluster 19: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles" "HPA046762: AB_2679792" "unprognostic (1.51e-3)" "unprognostic (1.54e-1)" "unprognostic (2.98e-3)" "unprognostic (2.79e-1)" "unprognostic (3.30e-2)" "unprognostic (2.31e-1)" "unprognostic (3.82e-3)" "unprognostic (3.63e-2)" "unprognostic (4.42e-3)" "unprognostic (2.69e-2)" "unprognostic (4.99e-2)" "unprognostic (4.40e-2)" "unprognostic (1.16e-3)" "unprognostic (1.10e-1)" "unprognostic (9.46e-2)" "unprognostic (1.59e-1)" "unprognostic (3.15e-2)" 5.3 9.9 9.4 2.1 10.6 20.5 2.6 19.5 15.1 2.4 0.0 13.6 5.5 3.4 2.5 2.3 2.4 4.2 25.7 10.6 6.3 5.7 130.0 3.7 0.4 4.9 5.7 1.7 7.4 6.4 3.4 4.4 4.2 5.3 10.2 3.1 8.3 2.9 13.0 1.6 8.5 3.6 6.9 0.7 5.0 4.8 9.9 0.3 7.3 9.7 0.5 4.7 1.3 12.6 22.4 12.6 1.7 2.6 0.8 0.0 2.9 0.8 0.5 2.8 6.5 9.1 10.4 0.0 10.7 0.4 20.0 0.2 7.4 1.1 4.8 15.5 4.1 0.5 9.2 2.0 0.8 0.4 0.6 1.2 0.4 2.1 0.0 4.4 0.0 1.2 19.8 1.2 0.6 1.9 1.3 0.1 1.7 0.7 6.9 0.0 35.7 0.6 12.0 14.4 4.5 3.6 15.6 10.8 6.7 1.8 11.7 0.4 0.2 0.3 9.0 1.1 7.9 3.8 8.0 0.0 1.5 0.1 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 9.4 10.6 19.5 15.1 10.6 6.3 4.9 5.7 4.2 6.9 9.9 12.6 5.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 77.9 0.0 0.0 0.0 0.0 8.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.5 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 TM7SF3 ENSG00000064115 "Transmembrane 7 superfamily member 3" Q9NS93 12 26971579-27014434 "Predicted intracellular proteins, Predicted membrane proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 258.0" "Cell type enhanced" "Detected in all" "Late spermatids: 148.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 553.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057640 Supported Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 7: Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA057640: " "unprognostic (4.24e-1)" "unprognostic (1.90e-2)" "unprognostic (1.04e-3)" "unprognostic (8.80e-2)" "unprognostic (5.82e-2)" "unprognostic (5.10e-2)" "unprognostic (1.83e-1)" "unprognostic (5.79e-2)" "unprognostic (2.86e-1)" "unprognostic (1.28e-1)" "unprognostic (1.01e-2)" "unprognostic (1.16e-1)" "prognostic favorable (1.32e-4)" "unprognostic (1.24e-2)" "unprognostic (1.53e-1)" "unprognostic (2.16e-1)" "unprognostic (1.58e-1)" 38.0 48.8 23.1 28.2 25.1 66.0 33.2 19.2 27.3 37.8 34.6 60.5 40.4 29.9 48.6 61.2 40.7 58.3 18.3 23.1 25.2 258.0 138.4 53.7 29.1 25.8 22.8 32.9 117.9 42.4 20.1 36.0 24.6 36.1 69.1 38.9 41.6 43.9 13.7 40.5 35.3 45.8 26.1 32.7 48.7 30.6 26.3 101.4 44.0 35.4 39.9 47.5 28.6 30.7 70.0 147.8 82.6 104.7 122.1 74.3 438.7 74.3 132.8 65.1 109.9 73.3 289.2 80.9 92.3 78.1 61.1 71.5 85.9 553.0 77.0 84.1 46.7 126.9 168.2 134.1 76.7 439.5 84.9 48.7 382.6 144.3 111.7 191.8 177.2 242.2 53.8 60.1 97.1 114.9 232.4 189.3 170.5 266.8 75.4 216.9 131.8 164.2 93.7 278.2 14.4 72.9 84.8 56.6 121.0 391.6 151.8 77.2 62.4 53.9 92.1 140.3 93.4 38.5 97.3 152.9 115.5 133.7 78.5 11.2 7.4 19.0 6.0 8.1 5.4 8.7 8.0 7.8 12.4 13.5 11.1 7.1 6.2 13.7 3.8 10.1 13.9 4.7 23.1 25.1 19.2 27.3 23.1 25.2 25.8 22.8 24.6 26.1 26.3 30.7 23.2 12.8 27.6 28.4 20.2 28.8 52.4 78.7 96.8 50.0 17.2 19.8 10.3 127.2 46.0 42.3 43.8 40.0 35.2 22.2 17.6 62.1 82.4 23.0 5.7 19.4 13.2 49.0 83.1 39.6 15.2 23.5 32.1 21.1 14.0 48.5 22.5 42.5 39.5 23.5 50.4 24.0 28.5 25.7 11.1 148.8 15.5 27.1 65.8 26.2 27.4 30.8 27.8 63.8 40.0 25.3 28.1 23.0 38.2 18.1 25.5 143.7 24.9 38.4 6.6 27.4 18.4 10.1 22.3 65.0 27.8 16.3 21.8 21.6 31.3 37.6 TMEM125 MGC17299 ENSG00000179178 "Transmembrane protein 125" Q96AQ2 1 43269983-43274002 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 75.7;pancreas: 89.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 121.8;Alveolar cells type 2: 136.9;Distal enterocytes: 72.7;Proximal enterocytes: 164.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 26.8;BEWO: 21.8;CACO-2: 20.6;CAPAN-2: 48.3;OE19: 31.3;SK-BR-3: 41.2;T-47d: 33.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015796 Approved Midbody,Cytosol Yes NA "Cluster 40: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "Midbody, Cytosol" "HPA015796: AB_1858081" "unprognostic (2.53e-3)" "unprognostic (8.70e-2)" "unprognostic (1.27e-1)" "unprognostic (1.52e-1)" "unprognostic (3.14e-2)" "unprognostic (8.50e-2)" "unprognostic (8.37e-3)" "prognostic favorable (5.11e-5)" "unprognostic (3.39e-1)" "unprognostic (1.11e-1)" "unprognostic (7.76e-2)" "unprognostic (1.26e-1)" "prognostic favorable (2.91e-9)" "unprognostic (1.86e-2)" "unprognostic (2.19e-1)" "unprognostic (4.04e-1)" "unprognostic (5.16e-2)" 0.3 0.7 17.4 3.2 32.2 0.2 11.5 27.6 29.9 16.4 12.8 21.2 35.4 1.6 18.3 10.9 15.5 11.3 0.9 17.0 20.7 16.4 1.1 75.7 0.3 31.5 28.5 1.4 89.6 22.2 31.0 4.4 29.0 22.0 21.0 0.1 31.8 7.1 0.0 12.9 27.5 0.8 22.6 0.3 27.4 1.5 26.8 0.4 44.9 0.0 2.5 2.9 3.4 42.8 26.8 0.0 0.0 0.0 0.0 0.0 21.8 0.0 0.0 0.0 0.0 20.6 48.3 0.1 1.2 0.0 0.0 11.7 0.0 7.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 12.1 0.1 0.1 1.1 31.3 0.0 0.0 0.0 0.7 0.4 8.5 12.4 0.1 0.0 41.2 0.0 3.6 33.1 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 17.4 32.2 27.6 29.9 17.0 20.7 31.5 28.5 29.0 22.6 26.8 42.8 0.2 121.8 136.9 0.0 0.9 0.0 2.3 18.0 0.6 0.0 30.4 15.2 0.5 42.9 56.0 16.5 0.0 33.5 0.1 72.7 17.6 39.1 3.7 20.1 1.4 0.6 21.7 0.0 0.2 38.5 2.2 0.6 45.3 13.1 1.3 4.9 0.0 0.0 2.4 0.0 0.2 63.0 34.6 0.0 0.2 7.9 0.3 0.6 0.0 0.0 0.6 1.7 1.0 0.0 55.3 22.7 40.1 1.2 0.6 12.2 164.2 33.9 43.8 0.0 0.0 0.0 2.3 1.4 0.3 2.1 0.4 7.3 1.0 0.1 38.6 9.1 TMEM131L "DKFZp586H1322, KIAA0922" ENSG00000121210 "Transmembrane 131 like" A2VDJ0 4 153466346-153636711 "Predicted membrane proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 49.4;lymphoid tissue: 48.3" "Cell type enhanced" "Detected in many" "Adipocytes: 13.6;Alveolar cells type 2: 9.6;B-cells: 9.9;dendritic cells: 13.2;Exocrine glandular cells: 9.3;monocytes: 16.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 105.2;MOLT-4: 99.9;U-698: 122.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043472, HPA048443" Uncertain Approved "Nucleoli fibrillar center,Vesicles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Vesicles "Nucleoli fibrillar center" "HPA043472: AB_2678496, HPA048443: AB_2680395" "unprognostic (1.12e-1)" "prognostic favorable (6.69e-6)" "unprognostic (1.71e-1)" "unprognostic (3.75e-2)" "unprognostic (8.37e-2)" "unprognostic (1.34e-2)" "unprognostic (1.90e-2)" "unprognostic (3.30e-2)" "unprognostic (3.23e-2)" "unprognostic (4.11e-2)" "unprognostic (4.37e-2)" "unprognostic (7.29e-2)" "unprognostic (4.35e-3)" "unprognostic (2.92e-2)" "unprognostic (3.39e-2)" "unprognostic (3.94e-2)" "unprognostic (3.51e-2)" 9.8 1.7 1.6 20.9 4.0 49.4 7.2 1.0 2.7 5.6 1.0 6.4 2.3 6.3 9.4 6.7 5.0 4.9 8.7 1.5 1.6 3.5 20.7 6.6 47.8 1.9 1.4 4.6 31.2 1.1 3.9 3.9 1.9 5.9 4.6 0.4 8.1 4.8 24.5 6.9 10.9 6.9 1.0 24.6 6.1 4.4 2.0 48.3 4.1 6.2 45.4 6.1 6.0 2.8 5.8 3.7 15.7 16.5 9.1 7.9 0.3 8.3 4.0 5.6 7.1 25.8 3.7 105.2 2.0 11.1 6.2 5.7 12.1 14.3 8.5 9.7 8.7 20.6 7.0 6.7 5.9 22.9 1.2 7.3 8.7 7.4 6.9 6.3 14.4 19.1 19.7 0.4 5.7 10.7 99.9 16.6 14.0 0.2 5.4 34.3 15.2 6.8 3.8 2.4 11.7 9.1 6.5 14.2 8.6 8.0 5.5 16.6 11.6 7.5 13.2 9.1 6.9 11.2 12.1 122.4 2.2 13.5 6.2 11.8 19.4 21.1 12.3 36.8 16.7 28.2 15.5 11.7 20.9 27.3 25.8 17.5 21.0 24.3 31.6 2.1 20.9 17.6 1.6 4.0 1.0 2.7 1.5 1.6 1.9 1.4 1.9 1.0 2.0 2.8 13.6 6.4 9.6 0.0 9.9 0.0 0.0 0.0 0.0 0.0 5.5 4.3 0.0 0.0 1.8 0.0 0.0 0.5 13.2 0.0 1.9 2.0 0.0 1.3 8.2 3.2 0.0 0.0 0.0 9.3 0.2 3.7 0.0 1.1 5.1 5.8 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 16.1 0.0 0.0 0.0 0.0 3.6 0.0 0.0 4.8 0.0 0.0 1.5 5.8 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 7.2 5.1 0.0 0.0 TMEM132A "FLJ20539, GBP, HSPA5BP1" ENSG00000006118 "Transmembrane protein 132A" Q24JP5 11 60924460-60937159 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 187.8;choroid plexus: 117.3" "Cell type enhanced" "Detected in many" "Astrocytes: 82.3;Ductal cells: 80.0;Horizontal cells: 254.1;Muller glia cells: 188.8;Rod photoreceptor cells: 165.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 174.1;MCF7: 177.8;SK-BR-3: 176.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051979, HPA060492" Enhanced Supported Approved Mitochondria No No 4100000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 38: EFO-21 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Mitochondria "HPA051979: AB_2681681, HPA060492: " "unprognostic (2.52e-2)" "unprognostic (2.01e-1)" "unprognostic (3.75e-2)" "prognostic favorable (1.98e-5)" "unprognostic (7.94e-3)" "unprognostic (3.74e-1)" "unprognostic (4.42e-3)" "unprognostic (2.39e-2)" "unprognostic (1.99e-1)" "unprognostic (1.30e-1)" "unprognostic (2.88e-1)" "unprognostic (5.98e-2)" "prognostic unfavorable (1.55e-9)" "unprognostic (3.31e-1)" "unprognostic (9.74e-2)" "unprognostic (1.50e-1)" "unprognostic (8.41e-3)" 7.7 21.0 137.9 8.6 134.3 0.3 7.7 119.4 187.8 12.0 117.3 5.5 2.5 13.6 1.2 19.5 4.8 5.5 13.7 134.1 136.9 13.9 2.1 10.1 1.7 154.5 131.2 18.8 6.8 12.4 23.6 16.6 126.4 9.4 1.0 28.1 25.9 1.8 3.9 6.1 6.0 3.7 123.0 5.7 32.4 6.7 144.6 1.3 4.8 3.1 5.4 4.2 9.2 114.7 37.0 50.7 44.1 88.0 3.6 1.7 78.1 27.0 84.5 24.6 20.3 18.0 33.3 0.3 174.1 7.8 79.9 67.6 10.3 46.0 9.5 0.5 14.8 1.1 33.3 32.7 30.8 0.5 1.3 7.7 8.6 45.8 7.1 38.7 42.1 7.0 2.3 2.3 7.8 177.8 0.9 0.2 58.5 1.2 26.9 0.4 18.6 4.2 36.4 18.7 43.7 104.1 19.3 176.4 16.7 22.3 123.7 0.6 49.4 9.5 43.2 2.7 52.3 0.4 0.3 2.1 78.5 0.1 46.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 137.9 134.3 119.4 187.8 134.1 136.9 154.5 131.2 126.4 123.0 144.6 114.7 11.8 0.0 0.0 82.3 0.6 1.3 2.7 56.2 5.7 62.8 17.1 11.7 0.8 4.3 22.2 5.5 18.8 31.4 0.1 0.7 1.9 80.0 0.5 12.4 7.0 11.9 15.6 0.0 22.6 13.3 28.7 7.7 9.2 27.7 0.0 57.5 11.4 0.0 3.3 254.1 29.1 2.7 20.3 0.3 1.0 1.0 1.8 0.7 0.0 7.5 3.1 188.8 0.0 12.1 3.3 63.2 1.6 3.4 0.0 9.7 0.0 0.4 4.0 165.3 6.6 4.4 15.2 1.2 4.0 5.7 0.9 27.1 0.3 19.2 2.3 7.2 TMEM135 FLJ22104 ENSG00000166575 "Transmembrane protein 135" Q86UB9 11 87037844-87328824 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 121.8;Excitatory neurons: 99.6;Inhibitory neurons: 93.7;Oligodendrocyte precursor cells: 123.1;Oligodendrocytes: 202.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 88.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056685, HPA069473" Uncertain Supported Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA056685: AB_2683208, HPA069473: AB_2686139" "unprognostic (1.55e-2)" "unprognostic (1.11e-1)" "unprognostic (2.70e-2)" "unprognostic (6.51e-2)" "unprognostic (3.10e-2)" "unprognostic (4.42e-1)" "unprognostic (1.45e-2)" "unprognostic (2.63e-1)" "unprognostic (2.19e-1)" "unprognostic (1.13e-1)" "unprognostic (2.26e-1)" "unprognostic (1.65e-1)" "prognostic favorable (9.02e-4)" "unprognostic (3.48e-2)" "unprognostic (7.34e-2)" "unprognostic (1.35e-2)" "unprognostic (1.80e-1)" 26.1 14.9 4.2 5.6 6.0 3.7 14.2 2.8 5.2 5.6 5.8 10.5 15.6 6.4 4.7 4.4 6.0 8.3 6.7 4.9 5.2 12.0 24.7 6.5 5.9 5.0 5.8 7.3 6.2 9.4 5.4 10.2 5.6 10.7 8.5 7.0 10.0 6.4 8.4 3.9 14.5 6.9 2.5 5.8 7.4 10.2 4.3 6.6 10.1 7.5 4.8 5.5 4.4 6.7 8.8 15.7 9.8 13.7 31.3 28.6 9.2 6.5 16.7 7.6 17.0 27.1 39.9 24.2 17.1 8.9 19.9 8.3 13.3 14.9 8.5 22.7 7.5 18.5 14.0 88.5 17.6 10.8 9.2 34.8 9.2 11.0 7.6 10.2 19.5 26.4 19.3 35.9 9.0 5.9 28.3 10.8 11.5 47.2 11.7 12.5 7.5 19.2 17.5 28.1 4.8 11.0 9.6 30.0 13.6 18.8 42.0 9.6 10.3 7.9 10.3 30.6 4.6 13.4 28.2 28.2 6.0 11.5 15.7 0.9 4.8 1.4 7.5 5.1 6.7 4.7 4.7 8.1 5.6 3.4 5.3 5.1 1.5 7.2 2.2 5.7 5.4 4.1 4.2 6.0 2.8 5.2 4.9 5.2 5.0 5.8 5.6 2.5 4.3 6.7 14.4 9.6 7.5 121.8 7.1 4.2 4.0 4.6 8.6 5.6 12.7 7.1 6.3 5.7 6.8 1.8 4.2 2.6 7.7 10.5 5.9 2.8 2.8 5.8 11.0 8.1 3.6 3.8 99.6 3.2 8.6 11.0 8.6 4.2 9.5 11.5 7.9 16.2 4.9 1.7 93.7 6.8 10.2 7.8 6.0 7.7 7.2 5.4 5.4 48.7 4.1 5.0 9.2 123.1 202.4 3.1 10.9 7.2 10.3 6.1 21.8 10.6 8.7 4.2 32.9 5.7 8.4 2.2 3.8 4.8 4.8 1.5 8.3 24.6 8.7 3.8 TMEM139 FLJ90586 ENSG00000178826 "Transmembrane protein 139" Q8IV31 7 143279957-143288048 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.8;kidney: 32.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 51.5;Ductal cells: 49.0;Proximal enterocytes: 90.7;Proximal tubular cells: 89.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 22.4;CAPAN-2: 40.8;EFO-21: 27.9;RPTEC TERT1: 70.5;SK-BR-3: 25.0;T-47d: 68.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036982, HPA036983" Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Focal adhesion sites" "HPA036982: AB_2675413, HPA036983: AB_10672275" "unprognostic (2.58e-1)" "unprognostic (4.38e-1)" "unprognostic (6.62e-3)" "unprognostic (1.41e-1)" "unprognostic (2.10e-1)" "unprognostic (2.16e-3)" "unprognostic (2.83e-2)" "unprognostic (4.90e-2)" "unprognostic (1.60e-1)" "unprognostic (2.82e-2)" "prognostic unfavorable (1.66e-4)" "unprognostic (2.89e-1)" "prognostic favorable (3.05e-5)" "unprognostic (1.73e-1)" "unprognostic (1.42e-2)" "unprognostic (2.83e-2)" "unprognostic (9.08e-3)" 1.1 2.7 1.9 2.2 6.4 0.0 3.2 6.6 3.2 8.9 2.9 5.7 33.8 1.2 1.3 0.4 6.8 7.2 3.3 1.6 4.1 32.2 9.2 5.1 0.2 10.5 6.9 0.4 8.7 6.8 1.8 5.2 8.9 0.9 4.5 0.8 4.8 3.1 0.1 1.2 19.3 0.4 5.9 0.9 2.5 3.8 5.7 0.0 7.2 0.0 0.1 1.8 0.3 13.9 22.4 1.6 0.3 0.1 0.0 0.0 14.3 0.2 0.0 0.0 0.0 5.2 40.8 0.3 27.9 0.0 1.8 18.5 0.0 9.3 0.0 0.3 0.0 0.0 2.4 3.1 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.9 0.0 1.3 0.0 0.5 0.0 1.5 1.6 1.0 0.0 0.5 1.6 0.4 0.3 0.0 70.5 5.6 0.4 0.1 1.1 25.0 0.2 0.5 68.5 0.0 0.0 0.3 0.7 0.0 0.1 0.0 0.1 0.3 0.3 0.3 0.3 0.0 0.0 0.2 0.0 0.8 0.0 0.1 0.3 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.8 0.0 0.6 0.1 1.9 6.4 6.6 3.2 1.6 4.1 10.5 6.9 8.9 5.9 5.7 13.9 0.6 16.0 5.9 0.7 0.2 0.1 2.1 2.8 0.0 0.2 8.2 15.5 2.3 27.1 5.4 51.5 0.0 30.5 0.2 28.9 35.2 49.0 14.8 16.2 1.6 0.7 3.6 0.0 0.0 4.7 5.2 0.4 3.1 17.9 0.0 2.2 1.4 16.2 1.9 0.0 0.2 6.7 0.0 0.6 0.3 13.6 0.0 0.7 5.4 0.0 1.1 7.7 0.0 0.0 5.2 30.6 23.3 0.0 0.0 1.2 90.7 89.1 3.8 0.1 0.0 0.0 0.9 0.1 0.2 0.6 0.0 6.4 0.8 0.7 12.9 1.4 TMEM159 promethin ENSG00000011638 "Transmembrane protein 159" Q96B96 16 21158377-21180616 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 128.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 121.2;Basal squamous epithelial cells: 176.4;Squamous epithelial cells: 127.5;Suprabasal keratinocytes: 150.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 67.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018033, HPA063509" Approved Approved Vesicles NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "HPA018033: AB_2204762, HPA063509: AB_2685026" "unprognostic (7.62e-3)" "unprognostic (2.42e-1)" "unprognostic (1.99e-2)" "unprognostic (1.06e-1)" "unprognostic (8.68e-2)" "unprognostic (6.80e-2)" "unprognostic (3.32e-1)" "unprognostic (2.93e-1)" "unprognostic (3.35e-1)" "unprognostic (2.93e-3)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.03e-1)" "prognostic favorable (8.11e-5)" "unprognostic (8.28e-2)" "unprognostic (1.28e-1)" "unprognostic (1.84e-2)" "unprognostic (1.57e-2)" 40.2 33.0 3.8 5.4 8.0 3.2 27.0 6.0 4.0 47.4 2.3 42.6 4.3 28.6 7.9 61.9 26.3 20.1 91.6 3.4 3.3 16.5 2.5 19.9 11.7 2.7 3.3 40.8 12.4 14.1 3.2 4.0 3.9 22.1 12.0 5.7 36.8 10.4 128.5 96.0 17.9 17.8 2.4 7.1 21.1 10.5 5.4 5.0 15.4 100.6 16.7 47.9 57.3 2.8 14.3 7.1 7.6 28.7 67.9 44.1 3.4 7.4 27.6 2.9 4.9 5.6 21.4 20.2 7.9 21.6 12.9 23.1 11.7 13.0 3.4 7.7 4.5 9.1 1.9 11.1 15.4 7.2 24.2 17.3 58.8 15.4 48.1 12.2 15.0 10.8 6.9 6.1 5.8 25.2 5.6 6.7 7.0 14.1 3.5 28.9 4.2 7.3 38.1 41.1 1.2 1.1 18.2 25.8 9.8 13.5 46.0 6.5 10.6 5.4 5.4 25.6 1.9 0.5 1.7 7.2 22.2 6.4 5.3 19.5 8.8 7.0 9.7 6.9 9.8 12.2 12.7 8.2 5.4 9.6 9.9 9.6 3.9 7.3 10.3 14.3 14.8 6.6 3.8 8.0 6.0 4.0 3.4 3.3 2.7 3.3 3.9 2.4 5.4 2.8 17.3 9.6 20.9 0.0 12.9 121.2 38.5 31.9 176.4 1.0 53.3 55.2 59.4 15.7 31.8 22.0 0.0 4.8 9.1 34.5 7.9 19.7 0.8 11.4 12.8 13.7 14.5 11.8 1.9 21.3 2.1 44.3 19.4 19.3 15.8 14.0 17.5 0.2 10.2 1.7 0.8 30.6 12.2 15.7 39.0 2.2 67.4 13.8 30.2 4.7 22.7 44.7 7.2 1.0 0.1 24.7 41.8 37.2 3.8 45.3 23.1 21.1 11.2 1.5 32.9 26.5 35.7 2.0 9.9 127.5 150.2 1.9 14.8 5.1 29.9 66.6 TMEM169 FLJ34263 ENSG00000163449 "Transmembrane protein 169" Q96HH4 2 216081866-216102783 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.0;retina: 3.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 14.4;Cone photoreceptor cells: 22.9;Excitatory neurons: 13.1;Inhibitory neurons: 13.9;Oligodendrocyte precursor cells: 11.1;Oligodendrocytes: 9.3;Rod photoreceptor cells: 11.6" "Cancer enhanced" "Detected in many" "glioma: 3.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 7.3;RPTEC TERT1: 12.3;SCLC-21H: 9.9;SH-SY5Y: 14.5" "Low region specificity" "Detected in all" "HPA062462, HPA062797, HPA070657, HPA074877" Enhanced Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Cytosol" Centrosome "HPA062462: AB_2732684, HPA062797: AB_2732690, HPA070657: AB_2686293, HPA074877: " "unprognostic (5.15e-2)" "unprognostic (2.93e-1)" "unprognostic (7.87e-3)" "unprognostic (4.69e-7)" "unprognostic (4.26e-2)" "unprognostic (1.17e-1)" "unprognostic (1.97e-1)" "unprognostic (4.43e-1)" "unprognostic (7.16e-2)" "unprognostic (5.72e-2)" "unprognostic (1.00e-1)" "unprognostic (1.35e-1)" "unprognostic (2.79e-2)" "unprognostic (7.51e-3)" "unprognostic (4.69e-2)" "unprognostic (1.54e-1)" "unprognostic (1.02e-1)" 0.5 1.0 1.4 1.0 3.0 0.3 0.2 1.5 2.6 0.7 0.0 0.4 0.7 0.3 0.7 0.2 1.0 0.8 0.4 2.3 2.1 1.8 1.7 0.6 1.0 2.6 2.1 0.3 0.3 0.1 0.8 0.1 2.8 0.4 0.3 3.4 0.2 0.3 0.3 0.5 0.6 0.4 1.0 1.0 0.2 0.3 1.7 1.0 2.6 0.3 0.7 0.2 0.1 2.8 0.0 0.3 7.3 0.1 1.0 0.0 0.0 0.3 0.2 0.2 0.8 0.3 2.4 0.0 5.8 0.3 0.4 0.1 0.9 0.0 0.2 1.4 0.3 2.9 0.1 1.4 1.9 0.1 0.5 0.6 0.6 0.5 0.7 1.8 0.0 0.9 0.0 0.3 6.3 0.8 0.2 0.1 4.1 0.0 0.0 1.4 2.0 0.0 12.3 0.0 9.9 14.5 0.3 0.1 5.7 4.0 0.5 1.0 0.0 0.2 0.4 0.0 0.4 1.7 2.2 0.4 1.9 0.2 1.4 0.8 1.0 0.1 1.2 1.0 0.9 1.5 2.0 1.4 0.0 1.4 2.1 0.9 2.3 0.3 3.2 0.1 3.7 0.7 1.4 3.0 1.5 2.6 2.3 2.1 2.6 2.1 2.8 1.0 1.7 2.8 0.3 0.0 0.0 2.0 0.9 0.0 0.0 0.0 0.0 14.4 0.1 0.5 0.8 4.3 0.0 5.5 22.9 0.1 0.3 0.0 0.0 0.6 0.0 0.4 0.4 0.2 4.9 0.0 13.1 0.0 0.0 0.2 0.5 0.5 0.0 0.0 1.4 0.8 0.4 0.0 13.9 0.0 0.0 0.3 0.0 0.1 0.0 0.5 0.0 3.7 0.2 2.2 3.1 11.1 9.3 0.1 0.6 0.4 0.3 0.1 0.3 2.8 0.1 11.6 0.0 3.6 0.4 0.0 0.7 0.0 0.0 0.0 0.8 0.1 0.2 0.1 TMEM176A "HCA112, MS4B1" ENSG00000002933 "Transmembrane protein 176A" Q96HP8 7 150800403-150805118 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 377.7;liver: 1170.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 1043.9;Paneth cells: 779.4;Proximal enterocytes: 1294.5;Proximal tubular cells: 1103.9" "Cancer enhanced" "Detected in all" "liver cancer: 210.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 146.5;intermediate monocyte: 98.4" "Lineage enriched" "Detected in many" 5 "monocytes: 146.5" "Cell line enriched" "Detected in some" 31 "HSkMC: 730.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008770 Approved Approved Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA008770: AB_2256120" "unprognostic (4.70e-2)" "unprognostic (7.71e-2)" "unprognostic (5.71e-3)" "unprognostic (6.09e-2)" "unprognostic (3.96e-3)" "unprognostic (1.44e-2)" "unprognostic (2.51e-1)" "unprognostic (2.32e-1)" "unprognostic (4.19e-2)" "unprognostic (1.99e-1)" "unprognostic (1.47e-2)" "unprognostic (4.37e-2)" "unprognostic (4.79e-1)" "unprognostic (1.23e-2)" "unprognostic (1.98e-2)" "unprognostic (2.64e-1)" "unprognostic (4.91e-2)" 76.6 33.1 46.5 124.8 48.0 6.8 49.3 49.2 50.8 45.7 39.1 143.9 113.2 18.6 17.9 28.5 48.9 129.8 90.9 43.6 56.2 377.7 1170.6 58.5 85.6 64.0 56.2 104.7 29.8 3.9 11.6 66.6 58.2 26.5 151.3 20.6 24.2 15.9 6.4 20.6 203.1 50.2 61.3 51.0 48.7 6.1 49.9 15.5 21.3 17.4 66.0 98.0 54.5 63.9 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 3.5 14.2 0.2 0.6 0.0 0.3 1.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.3 0.3 730.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.6 0.9 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 23.3 0.0 0.0 2.7 0.5 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 146.5 12.6 0.3 98.4 0.4 2.1 0.1 0.2 30.9 0.0 0.2 0.0 1.8 0.3 46.0 2.4 0.4 53.3 46.5 48.0 49.2 50.8 43.6 56.2 64.0 56.2 58.2 61.3 49.9 63.9 15.8 0.0 5.2 3.9 9.8 7.4 0.4 0.9 5.2 56.2 40.6 63.8 24.9 118.7 10.9 200.5 4.2 0.6 2.0 348.5 152.6 64.6 0.3 4.9 14.8 20.5 74.1 6.6 0.0 27.2 0.6 185.3 17.9 2.5 29.0 29.9 23.2 1043.9 52.2 0.0 0.2 237.7 73.2 56.9 26.2 1.5 60.3 109.4 5.4 1.9 313.0 80.8 1.0 1.0 0.0 56.0 779.4 7.5 0.9 1.8 1294.5 1103.9 10.6 5.3 0.0 5.7 32.8 0.9 1.6 2.9 8.4 1.4 6.4 0.1 262.4 2.7 TMEM176B "LR8, MS4B2" ENSG00000106565 "Transmembrane protein 176B" Q3YBM2 7 150791285-150801360 "Predicted membrane proteins, Transporters" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 1656.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 1171.9;monocytes: 502.3;Paneth cells: 762.4;Proximal enterocytes: 922.5;Proximal tubular cells: 976.5" "Cancer enhanced" "Detected in all" "liver cancer: 537.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 865.5;intermediate monocyte: 586.0" "Lineage enriched" "Detected in many" 5 "monocytes: 865.5" "Group enriched" "Detected in some" 17 "HSkMC: 642.7;THP-1: 215.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047509 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "Nucleoplasm, Plasma membrane" "HPA047509: AB_2680072" "unprognostic (5.21e-2)" "unprognostic (7.86e-2)" "unprognostic (1.30e-2)" "unprognostic (8.27e-2)" "unprognostic (3.35e-2)" "unprognostic (6.96e-2)" "unprognostic (7.23e-2)" "unprognostic (2.74e-2)" "unprognostic (5.31e-2)" "unprognostic (1.47e-1)" "unprognostic (5.72e-3)" "unprognostic (7.50e-2)" "unprognostic (3.11e-3)" "unprognostic (5.56e-2)" "unprognostic (2.17e-2)" "unprognostic (1.53e-1)" "unprognostic (4.05e-2)" 120.9 49.5 48.5 190.8 50.1 13.5 77.8 50.7 65.8 74.5 43.0 251.8 167.7 25.9 25.7 50.4 81.5 197.3 208.5 45.4 58.0 356.5 1656.5 95.6 177.5 69.2 60.1 143.1 53.6 7.3 22.7 115.0 64.5 48.9 244.9 34.1 42.5 28.3 11.0 34.7 286.6 99.0 65.0 87.0 94.5 11.1 52.2 26.1 33.6 36.1 93.7 158.6 92.4 73.2 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 2.2 25.7 0.4 0.8 0.0 0.1 0.6 0.1 0.1 0.0 0.1 0.8 0.4 0.0 0.0 0.6 0.8 0.2 642.7 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.7 0.1 0.9 0.5 0.1 0.0 0.1 1.0 11.8 0.1 0.0 1.9 1.4 0.6 0.3 0.2 0.2 0.0 215.7 0.0 0.0 3.2 0.5 0.2 0.4 0.2 0.6 0.0 0.3 0.0 5.3 865.5 50.5 2.3 586.0 3.4 2.5 0.6 0.7 164.3 0.6 0.7 0.4 8.6 0.6 309.3 7.7 0.6 498.5 48.5 50.1 50.7 65.8 45.4 58.0 69.2 60.1 64.5 65.0 52.2 73.2 22.2 3.2 9.3 14.4 16.9 12.6 0.5 0.9 5.7 156.9 52.2 74.0 73.7 190.1 14.4 375.2 2.1 0.9 2.8 419.4 166.3 95.1 18.5 6.1 14.5 19.8 128.1 13.5 0.1 34.0 1.0 243.7 14.8 2.1 54.4 61.9 22.9 1171.9 92.5 6.7 0.6 252.1 46.8 98.5 44.4 12.2 43.5 190.0 16.0 8.4 502.3 87.3 1.0 7.5 0.1 65.4 762.4 3.4 1.5 2.5 922.5 976.5 11.3 17.9 0.0 6.7 34.0 4.0 3.8 1.8 15.6 2.7 9.1 0.4 263.7 2.8 TMEM25 FLJ14399 ENSG00000149582 "Transmembrane protein 25" Q86YD3 11 118531041-118547280 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 149.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 35.9;SK-BR-3: 33.7;T-47d: 43.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA012163, HPA051562" Approved Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 6900000 "Cluster 48: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus, Vesicles" "HPA012163: AB_1858112, HPA051562: AB_2681535" "unprognostic (1.53e-2)" "unprognostic (7.18e-2)" "unprognostic (2.43e-1)" "unprognostic (6.69e-2)" "unprognostic (3.61e-1)" "unprognostic (6.50e-2)" "unprognostic (1.71e-1)" "unprognostic (4.45e-3)" "unprognostic (1.58e-1)" "unprognostic (3.42e-1)" "unprognostic (1.66e-2)" "unprognostic (8.19e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.15e-1)" "unprognostic (2.51e-1)" "unprognostic (1.26e-1)" "unprognostic (7.01e-2)" 6.9 25.3 35.0 3.8 36.0 2.2 14.6 33.9 44.3 14.9 32.2 16.0 46.0 15.3 25.7 11.1 13.7 8.9 8.9 37.5 36.7 18.6 23.1 9.9 4.8 32.1 30.3 23.4 17.6 23.3 29.5 6.0 32.0 15.7 3.7 22.3 21.0 18.3 18.5 8.7 35.2 10.8 31.5 5.3 13.3 6.5 35.1 5.1 15.9 9.9 5.3 14.4 11.6 35.1 3.4 0.7 5.8 9.5 6.0 0.9 5.6 5.2 9.9 4.9 9.8 27.1 18.8 0.3 20.1 5.3 10.9 14.8 0.0 18.3 4.4 11.9 11.1 0.5 5.4 6.0 16.0 0.3 0.5 7.3 10.9 5.3 0.9 35.9 7.2 13.7 2.6 11.7 4.9 4.1 6.0 0.5 4.9 0.1 12.8 8.1 4.2 12.3 25.3 0.3 17.0 11.5 5.1 33.7 0.1 8.7 43.8 0.6 2.5 2.1 10.6 0.4 1.6 11.7 8.3 3.1 0.4 0.2 0.2 0.7 0.2 0.2 5.1 0.2 7.1 4.0 7.3 2.9 0.5 2.6 10.0 5.4 0.4 7.4 0.2 3.4 6.0 3.5 35.0 36.0 33.9 44.3 37.5 36.7 32.1 30.3 32.0 31.5 35.1 35.1 5.1 6.4 3.9 11.1 6.2 5.7 10.7 14.7 13.1 27.7 27.7 30.6 6.1 14.3 9.3 16.5 29.2 37.1 4.8 0.9 11.7 16.6 2.8 4.1 5.0 6.4 11.4 5.2 20.1 6.4 16.9 8.7 2.6 5.5 8.9 18.0 3.6 9.6 2.9 11.8 22.0 7.8 10.2 0.0 1.9 5.5 23.3 1.1 7.2 2.8 3.4 28.8 5.2 8.5 6.5 5.0 5.5 23.3 5.5 5.5 149.1 25.6 7.4 41.1 0.0 12.1 7.5 3.9 5.2 4.0 3.7 16.3 4.7 15.3 15.0 5.7 TMEM30B CDC50B ENSG00000182107 "Transmembrane protein 30B" Q3MIR4 14 61277370-61281761 "Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 124.0;Prostatic glandular cells: 101.1;Urothelial cells: 131.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 68.7;CAPAN-2: 54.4;HaCaT: 31.7;HBEC3-KT: 39.0;hTCEpi: 29.1;MCF7: 44.6;RT4: 94.9;T-47d: 30.4" "Not detected" "Not detected" HPA043162 Uncertain NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "HPA043162: AB_10796688" "unprognostic (4.06e-2)" "unprognostic (2.46e-1)" "unprognostic (1.72e-1)" "unprognostic (3.47e-2)" "unprognostic (2.01e-1)" "unprognostic (6.20e-2)" "unprognostic (2.45e-3)" "unprognostic (3.43e-2)" "unprognostic (9.10e-2)" "unprognostic (2.20e-1)" "unprognostic (5.10e-2)" "unprognostic (2.26e-1)" "prognostic favorable (5.89e-5)" "unprognostic (2.21e-1)" "unprognostic (2.89e-1)" "unprognostic (2.60e-1)" "unprognostic (1.85e-1)" 3.9 1.6 0.5 3.7 0.7 0.4 14.8 0.5 1.0 16.4 0.9 29.1 43.3 3.8 28.2 14.1 15.2 23.9 2.0 0.3 0.7 12.3 12.3 14.5 1.2 0.6 0.5 2.5 35.7 59.1 18.2 5.7 0.5 21.9 26.1 0.3 27.7 13.4 1.2 8.6 34.4 1.7 0.5 0.7 42.2 2.6 0.6 5.3 50.0 1.9 4.4 16.1 9.3 0.4 68.7 0.2 0.0 0.0 6.7 1.6 0.1 0.1 0.0 0.0 0.0 11.6 54.4 0.0 0.1 0.0 0.0 31.7 0.0 39.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 29.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 44.6 0.0 0.1 0.6 28.2 1.6 0.0 1.5 0.2 0.0 94.9 11.2 0.1 0.8 25.6 0.1 1.9 30.4 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.3 0.1 0.0 0.0 0.7 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.5 0.7 0.5 1.0 0.3 0.7 0.6 0.5 0.5 0.5 0.6 0.4 0.6 28.9 31.9 0.0 0.6 64.9 124.0 19.5 61.5 0.0 32.2 16.5 1.9 47.1 24.5 40.5 0.0 28.0 1.1 90.8 13.7 24.8 0.9 23.8 3.9 3.9 23.4 0.0 0.0 37.2 11.4 5.5 62.7 45.3 2.5 0.7 4.2 14.1 2.0 0.0 0.0 73.1 20.3 1.0 6.8 1.6 8.7 1.5 5.4 1.0 0.6 2.9 2.1 0.0 0.1 31.9 75.3 79.0 0.4 101.1 73.6 1.0 22.7 0.3 13.1 2.4 5.4 5.9 3.6 43.3 63.6 35.8 3.6 0.9 64.7 131.9 TMEM44 DKFZp686O18124 ENSG00000145014 "Transmembrane protein 44" Q2T9K0 3 194587673-194633689 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 31.2;Hepatic stellate cells: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "basophil: 3.7;NK-cell: 8.1" "Group enriched" "Detected in many" 10 "granulocytes: 3.7;NK-cells: 8.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043718 Uncertain Approved Cytosol "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA043718: AB_10794662" "unprognostic (8.94e-2)" "unprognostic (1.01e-1)" "unprognostic (8.31e-3)" "unprognostic (4.53e-2)" "unprognostic (2.78e-3)" "unprognostic (9.29e-2)" "unprognostic (2.11e-3)" "unprognostic (1.17e-2)" "unprognostic (1.70e-2)" "unprognostic (3.37e-2)" "unprognostic (1.48e-2)" "unprognostic (4.75e-3)" "prognostic unfavorable (6.55e-13)" "unprognostic (1.23e-2)" "unprognostic (3.36e-1)" "unprognostic (1.65e-3)" "unprognostic (5.66e-2)" 10.3 2.9 9.8 2.3 11.7 5.2 8.9 7.8 12.4 6.9 7.1 11.0 2.7 5.6 13.7 5.6 5.4 4.5 9.6 10.3 10.1 6.0 3.4 11.3 3.0 9.9 9.7 4.9 3.5 0.9 2.6 7.4 10.0 5.2 7.2 0.6 7.7 2.2 3.2 3.6 6.8 3.2 8.8 9.3 4.9 2.2 10.5 2.0 5.6 2.3 1.6 5.3 5.9 9.2 11.1 9.1 13.4 14.2 4.8 16.2 11.8 8.2 15.3 6.8 10.8 5.0 21.8 2.0 38.9 10.0 20.3 12.6 4.5 6.4 4.6 18.1 6.3 12.4 10.6 3.8 8.7 3.9 18.9 10.0 6.8 15.4 6.8 32.8 28.2 12.1 3.4 0.5 22.9 10.1 5.9 9.9 6.9 11.1 14.8 11.5 8.4 0.3 7.2 6.3 3.7 7.7 6.1 1.9 12.6 5.6 9.0 8.5 33.7 20.8 7.6 6.4 11.2 1.5 1.2 4.0 31.4 15.0 10.4 3.7 0.2 0.2 0.4 0.1 0.0 0.1 0.1 0.6 0.0 0.2 0.0 0.2 0.4 8.1 0.3 0.4 0.0 0.0 9.8 11.7 7.8 12.4 10.3 10.1 9.9 9.7 10.0 8.8 10.5 9.2 22.0 0.0 2.3 3.3 2.1 0.5 3.3 4.9 1.8 0.9 2.8 2.3 1.7 1.5 6.0 5.5 2.1 9.5 1.7 31.2 0.0 5.7 0.6 2.3 3.7 23.8 6.0 4.0 12.7 4.9 4.0 6.0 22.4 2.0 17.7 10.6 53.2 0.6 3.5 0.0 5.4 25.2 6.1 1.3 3.4 0.3 3.1 1.5 1.8 12.2 0.1 0.5 2.1 2.5 1.5 14.9 21.0 1.9 1.3 6.0 3.9 0.4 7.5 0.6 6.6 1.8 3.6 0.5 6.5 2.4 0.6 8.8 1.9 6.0 21.0 6.3 TMEM53 "FLJ22353, NET4" ENSG00000126106 "Transmembrane protein 53" Q6P2H8 1 44635238-44674481 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 59.5" "Cell type enriched" "Detected in many" 5 "Late spermatids: 999.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "plasmacytoid DC: 99.4" "Lineage enriched" "Detected in all" 4 "dendritic cells: 99.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021134 Approved Approved "Golgi apparatus,Focal adhesion sites" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" "Focal adhesion sites" "HPA021134: AB_2205162" "unprognostic (5.28e-2)" "unprognostic (2.60e-1)" "unprognostic (5.37e-2)" "unprognostic (4.62e-2)" "unprognostic (3.93e-2)" "unprognostic (1.14e-1)" "unprognostic (2.82e-2)" "unprognostic (2.88e-2)" "unprognostic (2.19e-2)" "prognostic favorable (6.96e-4)" "unprognostic (3.00e-1)" "unprognostic (1.34e-1)" "prognostic favorable (1.02e-5)" "unprognostic (1.15e-3)" "unprognostic (1.84e-2)" "unprognostic (4.07e-2)" "unprognostic (2.29e-2)" 12.8 12.0 5.7 4.4 9.2 6.7 12.1 6.8 8.3 6.8 6.3 14.2 16.4 8.9 6.8 6.0 7.0 6.2 13.9 5.7 7.2 18.3 59.5 10.5 4.0 8.5 8.5 10.6 8.3 6.3 10.1 3.9 8.5 7.2 6.9 7.1 7.2 3.3 7.6 6.6 14.6 4.2 5.8 6.3 10.1 34.9 8.8 3.3 7.9 3.7 2.1 7.5 6.1 15.4 12.9 14.7 13.0 9.6 16.6 12.5 15.6 3.8 11.1 7.2 10.5 4.7 39.9 4.1 11.8 3.6 27.4 11.5 3.6 7.8 3.8 6.5 9.2 4.7 6.0 22.7 16.5 3.7 16.6 14.8 11.9 14.4 3.1 7.9 4.0 9.1 2.0 5.1 4.3 7.7 4.5 11.2 7.6 9.9 8.5 6.8 1.8 40.0 21.6 13.4 9.0 8.7 4.1 15.7 21.3 9.3 4.8 9.9 1.7 5.3 8.8 7.5 4.7 3.7 4.7 2.3 13.6 9.6 6.3 14.1 12.9 6.3 7.3 23.1 6.3 13.9 7.4 6.3 6.6 14.8 3.5 4.5 1.4 7.8 16.2 99.4 8.1 7.6 5.7 9.2 6.8 8.3 5.7 7.2 8.5 8.5 8.5 5.8 8.8 15.4 10.9 6.4 12.0 8.1 3.5 1.7 9.5 24.2 1.8 6.9 9.0 7.6 35.5 10.0 20.4 20.2 4.2 14.5 9.5 53.1 45.0 18.6 188.3 14.0 4.6 8.5 14.4 10.1 2.9 25.7 15.5 6.9 8.2 5.7 6.3 8.6 10.0 93.0 34.3 18.5 3.6 22.6 44.7 12.6 0.7 999.9 9.0 14.0 8.8 1.9 3.8 17.1 5.2 3.0 4.8 17.5 51.3 12.4 2.6 8.9 74.3 45.9 32.8 13.8 26.3 3.7 10.6 15.6 13.2 3.9 2.3 9.3 3.7 8.3 18.0 12.7 TNFAIP8L1 MGC17791 ENSG00000185361 "TNF alpha induced protein 8 like 1" Q8WVP5 19 4639516-4655568 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 31.3;liver: 34.2" "Group enriched" "Detected in many" 5 "Early spermatids: 327.0;Late spermatids: 862.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 33.9;HUVEC TERT2: 33.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.39e-1)" "unprognostic (1.14e-2)" "unprognostic (3.70e-1)" "unprognostic (9.03e-3)" "unprognostic (1.00e-1)" "unprognostic (2.80e-2)" "unprognostic (8.39e-2)" "unprognostic (3.88e-2)" "unprognostic (1.82e-1)" "unprognostic (4.70e-2)" "unprognostic (3.70e-2)" "unprognostic (3.25e-2)" "prognostic unfavorable (1.28e-7)" "unprognostic (7.65e-2)" "unprognostic (8.99e-2)" "unprognostic (2.30e-1)" "unprognostic (3.22e-1)" 6.8 3.1 8.6 5.0 10.3 2.4 5.3 7.9 9.9 4.9 4.6 31.3 8.8 4.3 3.3 5.7 23.1 3.6 8.1 10.1 6.9 8.8 34.2 8.2 6.8 5.7 6.3 3.9 2.6 1.3 4.4 5.2 5.8 3.5 4.4 0.5 2.3 1.5 4.8 6.8 12.5 5.5 4.9 17.5 10.8 13.9 8.1 4.7 5.4 5.6 5.4 7.0 4.5 7.8 17.2 5.4 7.3 11.6 2.2 3.5 3.8 3.1 5.7 6.3 5.7 9.6 6.3 8.2 1.5 4.8 6.8 8.5 4.6 5.5 5.9 13.6 2.1 18.8 3.3 17.6 3.2 2.8 33.9 4.5 1.6 5.7 3.7 7.9 33.1 10.0 10.0 11.8 7.3 5.5 3.4 13.8 3.7 12.0 7.3 9.4 4.7 3.8 6.3 1.5 2.9 6.5 1.5 4.4 6.4 5.4 3.1 7.4 24.1 3.2 12.9 4.9 12.3 6.4 8.4 7.3 6.2 8.6 9.3 3.2 2.3 7.0 1.4 3.3 2.5 3.6 2.5 1.5 1.9 2.6 3.1 2.7 1.0 3.1 5.1 1.6 3.3 2.0 8.6 10.3 7.9 9.9 10.1 6.9 5.7 6.3 5.8 4.9 8.1 7.8 25.8 0.0 10.3 0.7 12.0 11.6 3.2 7.1 2.8 3.5 3.7 3.4 2.6 8.6 10.0 3.7 0.0 3.8 10.0 4.5 1.9 2.9 327.0 96.9 6.3 46.2 7.7 11.0 5.3 1.2 7.4 5.6 1.1 5.7 49.5 7.1 63.5 41.0 7.7 3.3 2.8 4.3 10.2 11.3 19.3 862.9 8.4 12.5 5.4 6.5 13.5 0.9 11.3 1.0 1.0 2.7 1.4 7.2 6.5 3.4 6.9 20.5 109.9 4.6 19.7 8.3 8.1 10.4 7.6 5.0 11.2 9.3 10.4 5.8 11.4 2.6 TP53I11 PIG11 ENSG00000175274 "Tumor protein p53 inducible protein 11" O14683 11 44885903-44951306 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 461.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 41.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 133.9;SCLC-21H: 357.9;T-47d: 209.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059727, HPA061276" Uncertain Supported "Endoplasmic reticulum,Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum, Golgi apparatus" "HPA059727: AB_2684113, HPA061276: AB_2684461" "prognostic unfavorable (7.33e-5)" "unprognostic (1.87e-1)" "unprognostic (4.03e-2)" "unprognostic (3.44e-1)" "unprognostic (1.38e-1)" "unprognostic (2.66e-1)" "unprognostic (1.26e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (6.12e-4)" "unprognostic (6.55e-2)" "unprognostic (2.55e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (4.65e-4)" "unprognostic (2.14e-2)" "unprognostic (1.64e-1)" "unprognostic (2.09e-1)" "unprognostic (1.10e-1)" 77.8 18.6 41.1 20.4 17.8 29.6 63.7 40.5 27.5 32.8 19.7 43.4 20.2 36.0 4.9 24.5 45.5 24.7 71.7 24.7 27.6 27.9 10.5 45.7 12.7 16.9 30.2 20.0 37.7 5.6 20.3 23.9 24.1 47.8 27.5 2.2 42.7 11.7 15.0 30.3 38.8 32.8 19.5 61.2 29.9 16.2 18.3 9.1 41.0 10.3 12.3 29.2 32.0 13.4 0.0 82.0 27.3 38.2 28.0 2.2 0.5 23.9 46.3 8.5 10.7 5.1 0.5 14.3 20.5 6.9 21.7 14.5 14.6 0.5 2.8 28.0 12.3 1.3 0.8 0.0 52.5 0.8 101.1 118.0 1.9 11.5 4.9 2.0 29.6 31.6 2.2 0.1 11.3 73.0 1.4 133.9 48.9 53.4 26.9 60.3 16.1 7.2 0.0 5.2 357.9 13.0 44.2 96.8 0.1 33.9 209.9 7.5 6.8 55.8 39.3 87.3 0.1 0.5 0.5 0.3 0.1 7.8 16.1 0.0 5.9 0.0 5.2 5.8 7.0 8.0 1.0 5.1 4.7 8.4 0.0 1.7 41.2 8.1 21.2 25.3 0.9 4.8 41.1 17.8 40.5 27.5 24.7 27.6 16.9 30.2 24.1 19.5 18.3 13.4 52.2 22.4 30.9 0.3 13.2 10.8 36.9 12.9 13.6 1.7 29.5 22.7 10.3 24.3 23.7 42.3 0.0 57.8 8.7 31.0 1.9 32.0 96.5 9.0 6.3 45.1 36.0 3.2 2.7 21.3 22.0 15.0 23.0 9.7 0.0 7.8 76.8 1.6 35.7 0.0 10.2 30.1 38.7 7.5 20.3 461.2 12.2 9.3 10.6 5.6 11.5 0.8 0.0 0.0 0.5 28.5 16.0 7.5 2.1 28.6 17.7 0.1 14.5 0.8 13.1 1.4 22.4 3.4 6.3 4.4 4.4 68.3 8.7 5.1 54.0 45.7 TRAC ENSG00000277734 "T cell receptor alpha constant" 14 22547506-22552156 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in all" 7 "lymphoid tissue: 787.9" "Cell type enhanced" "Detected in many" "dendritic cells: 166.3;Rod photoreceptor cells: 75.9;T-cells: 428.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "MAIT T-cell: 2123.1;memory CD4 T-cell: 2939.7;memory CD8 T-cell: 2508.6;naive CD4 T-cell: 2671.8;naive CD8 T-cell: 2388.0;T-reg: 4379.2" "Lineage enriched" "Detected in all" 41 "T-cells: 4379.2" "Cell line enhanced" "Detected in many" "HDLM-2: 127.0;JURKAT: 294.7;NB-4: 83.1;U-266/84: 126.2;U-698: 62.1" "Low region specificity" "Detected in all" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "prognostic favorable (3.21e-4)" "prognostic favorable (4.87e-6)" "unprognostic (9.92e-3)" "prognostic favorable (4.15e-6)" "unprognostic (3.71e-2)" "prognostic favorable (5.25e-5)" "unprognostic (2.83e-2)" "unprognostic (9.81e-3)" "unprognostic (2.51e-3)" "unprognostic (1.00e-2)" "unprognostic (1.01e-1)" "unprognostic (4.99e-1)" "prognostic unfavorable (3.40e-5)" "unprognostic (2.13e-1)" "unprognostic (6.35e-2)" "unprognostic (1.33e-1)" "unprognostic (2.75e-2)" 17.5 7.7 5.4 157.5 14.8 29.5 16.9 6.9 3.9 12.0 2.4 33.6 46.6 9.3 39.3 17.2 10.0 42.2 45.3 2.0 2.0 10.5 16.5 47.0 394.3 3.4 8.2 7.3 3.3 1.9 11.4 2.3 4.0 15.3 43.4 112.7 25.8 5.5 3.3 19.5 78.3 10.4 2.5 134.1 54.9 7.2 2.2 787.9 12.2 2.7 287.6 58.4 9.7 2.3 0.3 0.0 11.6 0.0 0.0 0.0 0.2 0.1 0.4 0.3 0.4 1.8 0.0 11.4 1.5 0.0 0.2 0.0 0.2 0.1 1.1 127.0 0.0 0.2 0.0 0.0 0.0 16.4 0.8 0.0 0.0 4.3 0.2 0.0 3.1 294.7 0.4 0.1 1.2 0.0 45.7 83.1 3.1 0.1 0.6 22.9 2.8 0.2 0.7 0.0 0.0 0.2 0.0 0.0 1.1 1.7 0.0 1.6 8.3 3.4 0.7 0.3 1.0 2.7 126.2 62.1 1.0 0.5 0.1 24.5 10.2 9.8 520.5 6.7 2123.1 105.6 2939.7 2508.6 7.9 94.6 2671.8 2388.0 57.7 89.7 11.0 11.8 4379.2 2965.8 5.4 14.8 6.9 3.9 2.0 2.0 3.4 8.2 4.0 2.5 2.2 2.3 9.0 3.2 25.6 0.0 46.3 0.0 1.0 0.0 5.7 9.0 4.9 8.5 35.7 0.0 6.2 0.0 12.5 0.2 166.3 0.9 17.6 0.7 46.2 0.9 0.6 3.3 0.0 16.4 0.0 0.0 0.2 15.9 4.1 0.5 10.1 0.0 9.3 1.4 1.3 0.0 0.0 0.9 0.0 8.1 0.0 4.8 1.8 12.2 0.0 0.0 20.2 11.8 44.3 0.0 0.0 0.1 1.2 5.3 25.4 0.2 0.5 4.6 0.0 75.9 0.0 2.6 4.7 2.2 0.8 5.4 0.0 0.3 428.0 0.0 0.7 0.2 TRAF3IP3 T3JAM ENSG00000009790 "TRAF3 interacting protein 3" Q9Y228 1 209756032-209782320 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 130.5" "Cell type enhanced" "Detected in many" "B-cells: 133.8;dendritic cells: 124.7;NK-cells: 407.8;T-cells: 162.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 115.2;JURKAT: 64.2;Karpas-707: 46.2;MOLT-4: 60.9;NB-4: 68.7;THP-1: 64.1;U-266/70: 68.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040796 Enhanced Approved Vesicles NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA040796: AB_10794861" "prognostic favorable (4.11e-4)" "unprognostic (1.11e-1)" "unprognostic (1.51e-3)" "unprognostic (1.36e-4)" "unprognostic (2.67e-1)" "unprognostic (1.91e-5)" "unprognostic (3.83e-3)" "prognostic favorable (8.15e-4)" "unprognostic (5.30e-2)" "unprognostic (3.72e-2)" "unprognostic (5.00e-2)" "unprognostic (2.39e-1)" "unprognostic (1.38e-4)" "unprognostic (3.08e-1)" "unprognostic (2.93e-2)" "unprognostic (3.16e-2)" "unprognostic (4.21e-2)" 3.6 2.3 1.9 51.6 2.0 31.8 4.1 1.8 4.2 3.5 1.4 8.2 7.4 2.8 2.7 3.4 2.0 10.5 1.7 2.0 2.0 4.2 5.7 10.8 99.7 3.0 2.6 2.1 0.9 0.7 0.8 2.0 3.0 3.4 10.4 0.3 5.6 2.8 1.1 2.4 30.6 3.8 2.3 60.1 13.4 3.8 3.0 130.5 3.0 1.9 90.5 11.7 2.2 3.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 115.2 0.0 11.0 0.0 0.0 0.2 17.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 64.2 0.1 46.2 0.0 0.0 60.9 68.7 0.2 0.0 0.0 7.1 0.0 20.8 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 64.1 0.0 0.0 0.1 0.0 0.1 68.1 25.6 4.7 0.0 31.9 0.1 456.2 155.3 169.6 296.7 171.1 317.7 300.5 410.4 343.1 164.1 287.8 459.3 365.0 41.2 345.1 209.8 121.6 587.1 414.3 1.9 2.0 1.8 4.2 2.0 2.0 3.0 2.6 3.0 2.3 3.0 3.7 1.6 3.2 9.6 0.3 133.8 2.3 4.8 1.2 1.2 1.7 1.5 1.9 0.7 2.8 0.2 0.0 0.0 0.5 124.7 0.4 11.7 0.1 11.3 14.8 0.9 2.1 0.0 22.9 0.4 0.2 0.3 1.4 2.0 48.0 58.2 0.0 6.1 3.8 22.3 0.0 0.4 0.4 0.0 24.7 12.6 9.0 0.3 40.8 10.6 39.4 69.8 0.2 407.8 0.0 0.7 0.0 0.1 0.0 64.1 2.4 0.4 12.8 0.9 0.4 0.0 0.7 1.2 8.0 0.6 2.6 2.3 0.4 162.8 0.0 0.6 1.8 TRBC2 TCRBC2 ENSG00000211772 "T cell receptor beta constant 2" 7 142801041-142802748 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 115.8;lymphoid tissue: 190.2" "Group enriched" "Detected in many" 4 "B-cells: 164.7;dendritic cells: 358.8;NK-cells: 264.7;T-cells: 498.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "T-reg: 76.0" "Lineage enriched" "Detected in many" 7 "T-cells: 76.0" "Cell line enriched" "Detected in some" 45 "MOLT-4: 277.9" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "prognostic favorable (8.04e-5)" "prognostic favorable (1.80e-4)" "unprognostic (4.19e-3)" "prognostic favorable (3.42e-8)" "unprognostic (5.53e-2)" "prognostic favorable (6.58e-5)" "unprognostic (3.21e-2)" "unprognostic (1.30e-2)" "prognostic favorable (2.81e-4)" "unprognostic (7.53e-3)" "unprognostic (5.96e-2)" "unprognostic (2.63e-1)" "prognostic unfavorable (2.90e-7)" "unprognostic (2.09e-1)" "unprognostic (1.47e-1)" "unprognostic (2.30e-2)" "unprognostic (4.09e-3)" 18.9 3.1 0.4 3.9 0.3 1.5 8.6 0.1 1.2 11.9 0.1 21.2 1.7 8.7 0.0 14.6 15.7 2.2 4.9 0.3 0.0 9.6 12.7 32.3 8.6 0.2 0.3 18.3 3.5 0.1 4.0 0.0 0.2 14.2 2.7 0.0 7.9 0.1 3.3 6.5 115.8 0.5 0.1 190.2 16.9 8.7 0.3 109.2 16.4 1.2 10.9 14.0 12.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 3.5 0.0 0.0 0.0 0.0 277.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.9 0.0 0.0 14.4 0.0 35.0 8.1 47.6 47.3 0.3 7.7 46.6 40.3 2.0 10.5 0.1 0.0 76.0 42.4 0.4 0.3 0.1 1.2 0.3 0.0 0.2 0.3 0.2 0.1 0.3 0.1 8.3 9.6 52.4 0.0 164.7 0.0 0.3 0.0 1.8 0.1 6.2 9.7 4.8 5.7 3.7 1.8 0.0 0.4 358.8 1.4 0.0 2.9 1.0 1.1 0.8 4.0 0.0 16.6 0.0 1.3 0.1 10.8 8.6 0.9 20.2 0.0 15.0 1.6 0.4 0.0 0.0 0.8 0.0 9.0 0.0 4.2 63.6 18.9 0.0 0.0 19.0 15.6 264.7 0.0 0.0 20.1 0.1 70.3 30.6 0.4 0.1 2.2 2.9 0.4 65.7 4.2 12.4 0.1 0.8 1.3 0.0 0.3 498.0 1.4 0.9 0.2 TRO "KIAA1114, MAGE-D3, MAGED3" ENSG00000067445 Trophinin Q12816 X 54920462-54931431 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 31.1" "Cell type enhanced" "Detected in many" "Astrocytes: 9.4;Excitatory neurons: 14.6;Granulosa cells: 12.3;Inhibitory neurons: 20.0;Oligodendrocyte precursor cells: 17.1;Oligodendrocytes: 9.4" "Cancer enhanced" "Detected in many" "testis cancer: 11.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "NK-cell: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 37.1;SH-SY5Y: 33.8;SuSa: 74.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071449 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "Plasma membrane, Cytosol" "HPA071449: " "unprognostic (6.18e-2)" "unprognostic (1.01e-1)" "unprognostic (2.24e-2)" "prognostic unfavorable (4.41e-5)" "unprognostic (9.09e-3)" "unprognostic (2.72e-1)" "unprognostic (5.66e-2)" "unprognostic (1.46e-1)" "unprognostic (4.67e-2)" "unprognostic (3.18e-1)" "prognostic favorable (1.93e-4)" "unprognostic (1.17e-1)" "unprognostic (3.19e-2)" "unprognostic (1.67e-4)" "unprognostic (6.33e-2)" "unprognostic (3.27e-2)" "unprognostic (6.86e-2)" 3.9 3.0 13.9 1.3 10.6 1.0 3.7 0.8 23.7 9.5 0.9 3.2 0.9 13.4 6.6 1.6 5.3 4.2 2.4 9.3 17.2 3.9 16.8 2.1 1.6 6.2 5.1 17.5 7.1 5.3 24.4 4.3 6.9 5.5 2.1 6.2 1.5 5.2 31.1 1.2 1.6 8.6 3.4 1.0 2.0 2.6 12.6 4.7 10.1 1.0 1.6 2.5 5.5 13.3 0.0 0.3 37.1 0.1 7.1 9.8 0.0 2.1 13.1 2.0 0.7 0.0 0.0 0.0 5.3 13.8 3.1 0.2 0.3 0.6 1.0 0.1 23.3 18.0 0.0 1.5 2.7 0.0 0.1 22.8 0.0 12.0 0.0 11.8 0.9 9.1 0.0 0.2 14.0 0.0 0.3 0.1 19.6 0.1 0.0 11.3 16.4 0.1 3.5 0.3 25.3 33.8 0.0 0.5 3.1 74.2 0.0 2.2 0.0 15.7 15.9 0.2 2.2 5.8 0.9 0.0 2.3 0.0 13.8 0.0 0.0 0.0 0.4 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.1 0.2 0.0 2.2 0.1 0.9 0.0 0.1 13.9 10.6 0.8 23.7 9.3 17.2 6.2 5.1 6.9 3.4 12.6 13.3 0.4 0.0 0.0 9.4 0.3 0.4 1.4 0.8 5.2 4.2 0.5 1.9 1.8 0.0 1.9 3.7 0.0 0.8 0.2 0.0 0.0 1.7 0.4 0.3 7.9 1.9 0.0 0.0 14.6 0.2 0.6 7.0 0.5 0.5 1.3 12.3 0.4 0.0 0.5 8.4 20.0 0.0 0.0 0.0 0.4 0.6 5.9 0.2 0.0 1.0 0.1 2.2 0.0 17.1 9.4 0.2 0.0 3.8 0.1 0.4 0.0 0.4 0.0 0.9 0.0 1.5 3.3 1.2 1.9 0.1 0.1 0.7 0.7 2.9 0.0 0.3 TSPAN12 "NET-2, TM4SF12" ENSG00000106025 "Tetraspanin 12" O95859 7 120787320-120858402 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 91.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 118.6;Collecting duct cells: 103.0;Distal tubular cells: 189.8;Glandular and luminal cells: 87.5;Proximal tubular cells: 111.1" "Cancer enhanced" "Detected in all" "renal cancer: 44.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 53.0;HUVEC TERT2: 58.3;RH-30: 52.2;RPTEC TERT1: 90.5;RT4: 65.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051570, HPA058244" Uncertain Approved Vesicles,Microtubules NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Microtubules Vesicles "HPA051570: , HPA058244: AB_2683652" "unprognostic (2.40e-2)" "unprognostic (7.60e-2)" "unprognostic (3.66e-3)" "unprognostic (1.82e-2)" "unprognostic (3.97e-1)" "unprognostic (7.34e-3)" "unprognostic (1.60e-1)" "unprognostic (8.12e-2)" "unprognostic (1.23e-1)" "unprognostic (2.73e-1)" "unprognostic (1.63e-2)" "unprognostic (1.05e-1)" "unprognostic (9.53e-2)" "unprognostic (7.07e-2)" "unprognostic (1.51e-1)" "unprognostic (5.18e-2)" "unprognostic (1.43e-1)" 11.9 65.9 4.1 5.3 4.4 0.4 8.7 5.2 5.2 21.4 2.8 24.0 39.4 10.5 14.9 5.0 10.9 20.4 47.7 3.3 4.7 91.6 35.8 45.8 4.5 8.0 6.2 1.7 17.4 10.7 7.5 20.3 5.2 6.8 20.4 1.8 46.8 22.4 3.3 1.6 42.0 11.9 4.6 28.2 22.1 3.9 8.1 2.7 23.4 5.5 4.3 17.5 4.0 3.6 0.0 1.4 15.1 0.2 3.1 1.0 14.7 0.3 0.6 1.2 5.0 2.5 4.0 0.0 10.4 0.4 1.8 0.2 7.7 1.6 1.9 0.0 53.0 2.8 14.5 2.2 8.1 0.1 2.5 0.3 0.0 0.4 0.3 2.1 58.3 0.0 0.7 1.8 6.8 2.0 0.2 0.4 24.5 11.1 9.4 0.1 52.2 2.0 90.5 65.4 12.5 7.4 0.7 1.3 0.0 20.0 8.0 1.9 2.5 12.3 3.8 0.1 6.5 15.8 0.0 0.2 1.7 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 4.4 5.2 5.2 3.3 4.7 8.0 6.2 5.2 4.6 8.1 3.6 40.0 118.6 45.0 18.6 1.7 2.5 20.3 1.8 14.8 0.0 19.4 3.8 62.5 64.3 19.9 103.0 0.0 40.5 0.0 18.0 189.8 6.8 0.6 63.4 9.0 38.0 9.6 2.7 1.8 7.2 53.5 10.0 14.8 87.5 2.5 1.8 18.2 32.9 4.1 0.0 2.9 16.9 6.1 0.8 3.6 1.5 4.1 1.5 5.4 3.7 0.0 0.5 0.0 10.1 0.4 4.7 30.5 0.7 2.2 9.1 68.3 111.1 5.7 0.1 0.0 11.6 16.6 0.6 8.9 13.8 2.0 24.2 1.9 9.6 35.5 28.3 TSPAN6 "T245, TM4SF6, TSPAN-6" ENSG00000000003 "Tetraspanin 6" O43657 X 100627108-100639991 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 422.5;Granulosa cells: 684.8;Late spermatids: 1708.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.1" "Lineage enriched" "Detected in single" 6 "T-cells: 2.1" "Cell line enhanced" "Detected in many" "NTERA-2: 121.7;RT4: 153.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004109 Approved Approved "Nucleoli fibrillar center,Cell Junctions,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 15: RT4 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "Cell Junctions, Cytosol" "Nucleoli fibrillar center" "HPA004109: AB_1080301" "unprognostic (7.71e-2)" "unprognostic (8.97e-2)" "unprognostic (3.56e-2)" "unprognostic (2.57e-1)" "unprognostic (2.71e-3)" "unprognostic (5.93e-2)" "unprognostic (1.04e-1)" "unprognostic (1.09e-2)" "unprognostic (1.19e-2)" "unprognostic (1.80e-3)" "unprognostic (2.04e-3)" "unprognostic (8.76e-2)" "unprognostic (3.83e-3)" "unprognostic (4.28e-2)" "unprognostic (1.14e-1)" "unprognostic (2.24e-1)" "unprognostic (9.54e-3)" 29.6 18.2 7.2 4.9 7.5 0.6 34.2 7.2 8.9 26.9 26.8 40.0 19.7 20.5 14.8 46.8 39.5 16.7 8.6 7.4 9.0 36.5 70.2 11.3 3.0 8.7 9.3 53.4 20.2 34.7 36.9 20.0 8.2 18.9 33.1 6.2 52.6 10.3 4.6 9.7 18.5 7.2 8.9 8.7 14.8 74.9 9.6 4.2 19.3 5.3 6.8 32.2 24.1 12.0 24.8 23.0 80.6 42.2 28.7 16.6 30.4 12.9 17.3 20.3 47.6 54.9 37.7 0.0 53.3 12.2 16.9 19.9 0.3 19.7 25.8 0.1 33.3 3.8 14.9 62.0 17.1 0.1 2.5 30.2 9.3 19.5 6.6 34.4 49.3 0.0 0.0 0.1 21.7 19.8 0.1 0.3 121.7 35.4 18.4 0.0 35.5 0.0 33.0 153.5 4.7 20.3 11.6 10.0 18.5 61.9 16.6 3.3 12.7 16.0 24.4 24.3 8.6 0.1 0.2 0.3 13.4 0.0 11.5 0.3 0.0 0.1 0.3 0.0 1.1 0.1 0.8 0.3 0.0 0.1 2.1 1.2 0.3 0.1 0.1 0.1 0.0 0.3 7.2 7.5 7.2 8.9 7.4 9.0 8.7 9.3 8.2 8.9 9.6 12.0 147.0 3.2 10.1 14.4 2.3 7.1 41.0 75.7 29.0 0.6 72.5 46.1 8.2 50.1 89.4 93.8 0.0 28.7 1.1 94.9 23.5 80.3 422.5 54.0 21.4 37.4 33.6 4.8 0.9 12.6 40.7 25.6 21.9 19.2 0.0 684.8 47.5 104.0 4.5 0.0 0.8 47.9 193.3 10.2 3.1 1708.3 32.9 3.1 10.6 1.0 1.0 48.2 0.0 9.5 0.4 18.7 55.5 35.7 0.3 33.0 43.5 43.8 193.9 1.9 19.7 17.1 43.1 20.9 32.4 23.3 5.4 13.5 2.5 49.4 94.3 89.7 TTBK1 KIAA1855 ENSG00000146216 "Tau tubulin kinase 1" Q5TCY1 6 43243481-43288258 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 20.7;pituitary gland: 9.2" "Cell type enhanced" "Detected in some" "Astrocytes: 10.7;Bipolar cells: 6.6;Excitatory neurons: 12.1;Inhibitory neurons: 13.0;Oligodendrocyte precursor cells: 12.1;Oligodendrocytes: 12.4" "Group enriched" "Detected in some" 4 "glioma: 3.0;liver cancer: 0.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "SCLC-21H: 20.3;SH-SY5Y: 7.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031735, HPA031736" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA031735: AB_2674019, HPA031736: AB_10670294" "unprognostic (1.68e-1)" "unprognostic (7.88e-3)" "unprognostic (7.01e-2)" "unprognostic (1.62e-3)" "unprognostic (2.18e-1)" "unprognostic (2.24e-4)" "unprognostic (2.46e-3)" "unprognostic (3.01e-2)" "unprognostic (3.09e-1)" "unprognostic (1.85e-1)" "unprognostic (3.01e-2)" "unprognostic (2.12e-4)" "unprognostic (7.42e-2)" "unprognostic (3.68e-1)" "unprognostic (1.32e-1)" "unprognostic (2.64e-3)" "unprognostic (3.04e-4)" 0.0 1.3 11.8 0.2 10.6 0.0 0.0 3.8 20.7 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.2 0.1 12.0 1.1 0.4 1.9 0.0 0.1 5.0 2.2 0.0 0.2 0.3 9.2 0.0 3.5 0.1 0.1 3.0 0.0 0.1 0.0 0.0 2.8 0.0 0.5 0.1 0.1 0.9 6.0 0.0 0.0 0.0 0.2 0.0 0.0 11.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 1.1 0.0 0.3 0.0 0.0 0.7 0.0 0.2 0.1 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.3 0.6 0.0 0.1 0.0 0.0 0.0 0.0 20.3 7.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 10.6 3.8 20.7 12.0 1.1 5.0 2.2 3.5 0.5 6.0 11.0 0.0 0.0 0.0 10.7 0.0 0.0 0.1 0.0 0.0 6.6 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.1 0.1 0.1 0.0 0.0 12.1 0.2 0.0 0.1 0.0 0.0 0.0 2.2 0.4 2.5 0.1 5.0 13.0 0.2 0.0 0.0 0.4 0.5 0.0 0.0 0.0 2.8 0.0 1.4 0.0 12.1 12.4 0.0 1.1 0.0 0.0 0.0 3.8 3.5 0.0 0.5 0.0 0.0 0.1 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.6 0.0 TTC31 FLJ12788 ENSG00000115282 "Tetratricopeptide repeat domain 31" Q49AM3 2 74483073-74494559 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041783 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 52: Non-specific - Transcription" Cytosol Nucleoplasm "HPA041783: AB_10794306" "unprognostic (2.38e-2)" "unprognostic (7.44e-2)" "unprognostic (3.87e-2)" "prognostic unfavorable (6.70e-4)" "unprognostic (2.64e-1)" "unprognostic (7.78e-2)" "unprognostic (1.05e-1)" "unprognostic (2.89e-2)" "unprognostic (6.56e-2)" "unprognostic (7.22e-2)" "unprognostic (7.61e-2)" "unprognostic (1.13e-2)" "unprognostic (1.46e-3)" "unprognostic (9.61e-2)" "unprognostic (3.24e-1)" "unprognostic (4.83e-2)" "prognostic favorable (2.49e-4)" 6.4 4.8 3.5 8.4 3.9 9.0 4.8 3.4 4.3 5.4 3.8 7.9 11.1 5.9 4.5 6.1 5.9 5.9 5.7 3.3 3.6 6.0 18.7 6.8 9.8 4.3 3.8 6.3 7.9 9.2 3.2 9.2 3.9 5.2 8.2 4.8 4.7 4.5 3.7 8.8 9.9 7.4 3.8 8.2 7.5 3.2 3.8 9.7 4.8 3.9 10.6 5.7 4.6 4.5 16.0 13.1 11.7 6.3 7.3 17.0 12.9 11.2 11.4 16.2 11.9 11.3 13.0 20.6 6.4 9.5 14.2 11.8 9.5 10.5 11.0 23.0 8.3 22.4 12.9 24.9 11.0 10.1 21.5 11.5 13.7 14.0 9.8 14.3 11.0 12.0 15.0 11.5 12.0 13.7 17.4 9.2 7.6 12.2 7.9 13.7 24.0 11.5 11.5 11.8 5.6 16.5 7.9 12.4 10.2 7.4 9.7 6.2 17.6 12.5 18.7 9.5 12.6 13.6 10.8 14.1 13.5 12.5 11.4 4.9 8.3 6.1 6.5 8.1 7.2 7.0 4.9 6.2 8.1 4.7 4.6 5.4 0.8 6.6 8.7 4.4 7.3 7.4 3.5 3.9 3.4 4.3 3.3 3.6 4.3 3.8 3.9 3.8 3.8 4.5 5.4 16.0 9.2 7.2 10.8 2.8 4.1 5.2 4.6 11.1 5.2 5.0 3.5 14.3 7.8 9.2 39.6 8.3 9.8 7.8 1.9 5.8 4.6 3.8 8.0 6.7 6.1 13.3 3.0 5.5 5.3 6.0 7.1 5.9 19.0 8.8 4.6 20.8 8.3 5.0 3.4 5.9 6.1 7.9 3.5 5.0 6.2 7.5 3.6 10.3 13.2 9.2 19.6 2.5 4.4 5.9 9.4 5.7 9.6 3.1 13.9 6.0 4.3 23.6 6.6 7.3 5.3 8.3 10.0 4.2 3.3 8.1 9.8 8.2 6.5 3.8 TUBE1 "dJ142L7.2, FLJ22589, TUBE" ENSG00000074935 "Tubulin epsilon 1" Q9UJT0 6 112070663-112087529 "FDA approved drug targets, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 199.6;Spermatocytes: 97.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-2197: 48.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA032073, HPA032074" Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA032073: AB_10601773, HPA032074: AB_10601216" "unprognostic (4.79e-2)" "unprognostic (1.61e-1)" "unprognostic (3.76e-2)" "unprognostic (1.29e-1)" "unprognostic (2.22e-2)" "unprognostic (7.36e-2)" "unprognostic (1.22e-1)" "unprognostic (8.36e-3)" "unprognostic (2.18e-1)" "unprognostic (1.04e-1)" "unprognostic (4.99e-3)" "unprognostic (1.70e-1)" "unprognostic (5.15e-3)" "unprognostic (1.64e-1)" "unprognostic (7.68e-2)" "unprognostic (2.50e-1)" "unprognostic (1.59e-3)" 12.3 9.0 9.8 5.0 10.1 4.1 11.0 11.7 16.8 15.6 9.9 11.8 5.0 17.0 8.3 6.8 16.4 8.8 17.5 9.7 10.0 12.3 40.1 7.9 7.3 10.4 10.2 15.2 10.9 7.5 14.4 9.1 10.4 11.0 6.2 10.1 6.7 8.4 5.8 11.3 7.6 10.3 10.2 6.9 11.7 27.1 10.1 4.8 10.6 4.8 5.4 12.6 10.4 11.4 2.1 2.8 7.6 24.0 17.5 9.2 6.3 8.6 13.7 5.9 11.6 4.2 4.2 8.0 5.4 3.6 9.2 6.4 8.7 3.8 12.2 4.1 7.8 2.8 2.0 6.1 25.0 15.4 10.1 10.0 25.1 8.1 20.9 8.5 7.4 22.8 15.6 10.8 4.8 1.7 8.8 20.5 7.6 12.1 5.2 10.3 4.7 5.2 9.0 2.0 11.5 10.1 7.0 6.0 26.4 6.6 4.8 36.5 4.3 5.3 4.9 48.2 9.2 3.2 1.1 8.7 7.7 18.2 13.8 0.0 0.4 1.1 1.1 0.5 3.3 1.5 2.4 1.5 0.8 1.1 3.2 2.7 0.3 1.8 0.8 0.6 2.5 0.9 9.8 10.1 11.7 16.8 9.7 10.0 10.4 10.2 10.4 10.2 10.1 11.4 27.6 6.4 16.7 25.8 13.4 24.6 17.8 12.3 15.4 23.0 15.0 13.3 17.5 11.5 13.5 22.0 35.5 4.1 9.8 6.8 15.6 12.5 199.6 12.1 12.0 16.7 6.1 19.1 58.2 18.0 12.3 18.8 7.7 7.7 16.5 11.5 18.5 71.9 7.2 13.5 68.3 11.4 4.1 6.7 10.2 49.8 15.5 6.2 7.2 21.5 4.6 11.8 9.2 31.7 82.0 12.6 9.0 19.9 10.9 13.2 12.7 25.6 14.6 28.0 19.7 13.3 13.4 97.0 27.0 12.7 12.5 3.3 14.8 35.0 8.0 14.8 TUSC3 "MagT2, MGC13453, MRT22, MRT7, N33, OST3A, SLC58A2" ENSG00000104723 "Tumor suppressor candidate 3" Q13454 8 15417215-15766649 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 472.9;Extravillous trophoblasts: 321.8;Syncytiotrophoblasts: 783.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049851, HPA049974" Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA049851: AB_2680913, HPA049974: AB_2680976" "unprognostic (3.31e-2)" "unprognostic (7.17e-2)" "unprognostic (2.94e-1)" "unprognostic (1.42e-1)" "unprognostic (4.46e-1)" "unprognostic (2.34e-1)" "unprognostic (7.15e-3)" "unprognostic (5.02e-2)" "unprognostic (7.39e-2)" "unprognostic (4.79e-2)" "unprognostic (1.59e-3)" "unprognostic (4.81e-1)" "unprognostic (1.60e-3)" "unprognostic (5.99e-3)" "unprognostic (1.17e-1)" "prognostic favorable (7.86e-4)" "unprognostic (1.55e-1)" 23.3 68.8 18.7 8.4 18.4 0.1 28.3 22.3 17.1 25.0 46.6 14.5 9.3 31.9 100.8 11.8 57.6 16.7 34.9 17.1 48.2 25.2 6.9 18.4 6.8 8.9 11.6 73.6 35.0 54.0 69.6 80.5 8.9 46.4 15.5 40.9 12.1 29.7 4.5 8.2 8.2 32.5 7.7 5.3 10.8 23.2 21.0 7.5 9.5 5.7 5.6 34.0 13.0 8.0 52.1 38.4 104.3 96.7 125.2 126.7 0.2 74.9 168.8 85.2 139.3 0.1 0.1 0.7 24.5 105.9 92.4 39.3 37.5 76.1 116.0 0.1 49.8 0.0 30.1 6.0 51.9 0.2 5.6 111.8 22.8 121.0 43.1 113.7 6.9 15.9 70.9 15.6 123.2 41.2 20.6 0.4 49.2 0.0 33.5 24.8 88.7 0.3 108.3 127.1 40.7 74.6 0.0 40.6 56.5 76.2 49.8 0.2 29.0 71.9 71.3 31.3 36.5 0.0 10.0 0.4 1.2 0.0 102.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.7 18.4 22.3 17.1 17.1 48.2 8.9 11.6 8.9 7.7 21.0 8.0 88.6 0.0 10.3 13.4 0.6 9.9 61.1 123.5 63.7 50.4 40.0 52.1 47.5 18.6 47.0 79.1 8.4 472.9 0.9 2.1 17.6 179.0 11.5 100.8 48.6 36.2 95.7 0.0 141.0 12.2 321.8 53.4 7.7 35.0 1.3 39.3 7.5 0.0 41.8 32.0 155.3 26.3 95.6 0.0 6.3 7.6 34.8 1.5 24.9 24.4 1.6 35.9 0.0 61.3 3.9 23.8 4.1 23.0 2.6 63.8 0.0 23.7 172.4 28.1 39.5 2.0 49.7 60.9 47.4 26.2 4.1 783.8 1.6 46.6 7.8 51.4 TYSND1 "MGC34695, NET41" ENSG00000156521 "Trypsin like peroxisomal matrix peptidase 1" Q2T9J0 10 70137981-70146700 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 120.7;Late spermatids: 227.4;Spermatocytes: 124.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 27.5;PC-3: 41.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030304 Approved Uncertain Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Centrosome" Cytosol "HPA030304: AB_10670560" "unprognostic (4.75e-3)" "unprognostic (4.30e-2)" "unprognostic (2.44e-2)" "unprognostic (7.69e-2)" "unprognostic (1.84e-1)" "unprognostic (4.53e-2)" "unprognostic (2.02e-2)" "unprognostic (1.55e-1)" "unprognostic (1.33e-1)" "unprognostic (1.10e-1)" "unprognostic (1.59e-2)" "unprognostic (2.80e-1)" "unprognostic (1.37e-1)" "unprognostic (9.26e-3)" "unprognostic (1.91e-1)" "unprognostic (1.30e-1)" "unprognostic (1.69e-2)" 5.7 6.0 1.4 1.9 1.3 0.9 5.4 1.7 1.8 5.8 1.1 4.9 3.3 4.1 0.6 11.8 4.5 0.6 2.9 1.0 0.9 5.2 6.4 2.8 1.8 2.1 0.7 4.2 6.2 1.3 3.4 1.3 0.8 5.7 0.6 0.2 5.7 1.5 3.2 11.4 5.0 0.3 0.6 5.4 3.9 14.2 0.9 1.2 4.6 0.5 0.9 4.8 6.5 1.4 16.0 10.2 0.8 6.2 1.0 0.9 3.7 2.2 1.4 2.0 1.8 6.2 9.6 13.8 6.0 0.5 0.6 27.5 1.0 3.9 0.4 8.9 9.5 0.7 2.9 3.3 2.4 1.2 0.1 2.0 7.6 1.7 3.1 1.2 1.4 4.9 0.1 4.3 0.8 6.3 5.3 5.6 3.3 3.5 41.7 8.9 2.6 6.2 0.9 2.6 7.4 3.8 6.7 14.8 6.1 0.2 9.4 1.1 2.6 2.5 1.7 4.8 8.7 14.9 9.9 7.0 2.9 6.2 1.8 0.0 0.8 0.7 3.8 1.2 2.4 3.0 2.2 2.8 0.9 3.3 3.0 2.6 0.3 2.0 0.7 0.7 2.6 1.4 1.4 1.3 1.7 1.8 1.0 0.9 2.1 0.7 0.8 0.6 0.9 1.4 6.1 9.6 5.3 4.9 12.6 14.3 14.5 13.3 14.8 6.9 14.8 16.9 4.2 27.1 7.8 11.0 0.0 35.2 15.5 14.6 17.6 7.8 120.7 5.5 6.8 6.3 14.3 5.0 6.7 9.5 9.8 7.5 5.1 6.3 13.4 9.3 6.8 16.5 12.1 0.0 6.0 12.1 16.2 10.7 6.6 227.4 9.3 8.2 12.4 6.5 6.1 7.0 12.3 11.6 5.5 5.5 11.6 7.9 7.5 14.5 19.2 16.5 3.9 4.4 6.6 6.9 6.1 124.7 12.5 22.4 18.5 16.7 14.0 10.6 21.0 8.8 UBASH3A "CLIP4, STS-2, TULA" ENSG00000160185 "Ubiquitin associated and SH3 domain containing A" P57075 21 42403447-42447684 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 18.9" "Cell type enhanced" "Detected in some" "dendritic cells: 5.9;Erythroid cells: 3.8;T-cells: 20.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "gdT-cell: 12.9;MAIT T-cell: 22.9;memory CD4 T-cell: 28.2;memory CD8 T-cell: 24.8;naive CD4 T-cell: 32.2;naive CD8 T-cell: 24.0;T-reg: 27.9" "Lineage enriched" "Detected in many" 12 "T-cells: 32.2" "Group enriched" "Detected in some" 7 "HEL: 23.0;JURKAT: 39.0;MOLT-4: 47.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA035367 Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm "Golgi apparatus" "HPA035367: AB_2732466" "unprognostic (5.14e-4)" "unprognostic (3.91e-4)" "unprognostic (1.57e-2)" "unprognostic (4.10e-5)" "unprognostic (4.33e-2)" "unprognostic (1.85e-6)" "unprognostic (5.54e-4)" "unprognostic (1.46e-3)" "unprognostic (6.17e-4)" "unprognostic (2.47e-3)" "unprognostic (1.94e-2)" "unprognostic (1.81e-1)" "unprognostic (2.37e-6)" "unprognostic (1.65e-1)" "unprognostic (7.96e-2)" "unprognostic (3.24e-2)" "unprognostic (4.17e-2)" 0.4 0.6 0.0 5.2 0.0 2.5 0.2 0.0 0.1 0.5 0.1 0.8 1.6 0.5 0.0 0.4 0.4 2.0 0.4 0.0 0.1 0.4 0.7 1.7 11.1 0.2 0.0 0.3 0.1 0.0 0.1 0.2 0.1 0.4 0.9 0.0 0.9 0.1 0.2 0.3 2.4 0.1 0.1 4.4 1.9 0.1 0.0 18.9 0.5 0.1 5.1 1.7 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 23.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 39.0 4.4 0.0 0.0 0.0 47.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 12.9 0.0 22.9 0.1 28.2 24.8 0.0 0.0 32.2 24.0 0.5 2.5 0.1 0.1 27.9 10.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.5 0.0 0.8 0.4 0.0 0.8 0.0 0.0 0.2 0.3 1.0 0.0 0.8 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.1 0.6 0.0 0.3 0.0 3.8 0.0 0.0 0.0 0.4 1.1 0.5 1.3 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.2 0.1 0.6 0.0 0.3 0.0 20.5 0.0 0.0 0.0 UCP2 "BMIQ4, SLC25A8" ENSG00000175567 "Uncoupling protein 2" P55851 11 73974672-73982843 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 278.1" "Cell type enhanced" "Detected in many" "dendritic cells: 404.4;Enteroendocrine cells: 297.3;Erythroid cells: 695.6;Hofbauer cells: 442.2;Kupffer cells: 326.6;monocytes: 533.6;NK-cells: 509.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 360.2;SK-BR-3: 395.6;U-698: 293.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025583, HPA075202" Approved Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 3: T-cells - Adaptive immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "CAB025583: , HPA075202: AB_2732284" "unprognostic (1.13e-1)" "prognostic favorable (4.65e-5)" "unprognostic (8.07e-2)" "unprognostic (1.21e-2)" "unprognostic (1.08e-1)" "unprognostic (1.15e-2)" "unprognostic (1.92e-1)" "unprognostic (1.82e-3)" "unprognostic (2.07e-1)" "unprognostic (4.59e-2)" "unprognostic (1.13e-3)" "unprognostic (1.37e-1)" "prognostic unfavorable (7.80e-6)" "unprognostic (3.77e-2)" "unprognostic (1.58e-1)" "unprognostic (3.77e-3)" "unprognostic (3.88e-3)" 70.9 20.5 12.2 142.9 14.6 132.8 37.6 12.9 24.1 41.3 22.1 33.2 53.4 17.4 7.6 17.7 175.7 42.3 14.1 12.1 15.9 34.9 26.2 69.3 278.1 19.7 19.8 4.9 12.6 8.1 13.8 27.3 19.8 19.7 44.8 6.9 42.7 23.0 99.1 9.2 56.6 30.4 17.6 183.1 55.2 14.5 22.4 217.3 45.1 141.7 240.2 73.6 4.9 26.1 0.9 78.7 20.2 43.5 9.5 0.0 11.6 14.1 9.3 54.9 14.8 153.1 59.0 360.2 165.1 19.5 5.5 3.5 13.3 0.0 28.6 97.1 5.6 241.5 26.4 28.3 32.2 123.9 77.5 8.9 0.0 43.9 0.0 11.0 5.7 144.6 101.5 119.0 9.5 147.5 108.5 55.8 12.8 9.0 21.7 99.7 120.7 202.0 150.4 211.0 23.6 32.3 68.2 395.6 26.6 55.9 123.3 79.3 10.0 0.2 59.7 14.4 21.5 48.4 24.4 293.8 7.2 45.0 0.4 809.1 1116.7 1465.3 1462.8 1945.8 925.0 1914.8 1176.3 1233.5 1228.7 1851.8 1092.9 1143.1 154.2 1816.8 1692.3 3009.5 2589.5 2966.6 12.2 14.6 12.9 24.1 12.1 15.9 19.7 19.8 19.8 17.6 22.4 26.1 4.7 3.2 27.6 0.3 287.4 3.4 2.7 20.2 0.6 0.9 30.9 19.8 5.2 5.7 43.9 92.0 8.4 8.3 404.4 6.2 7.9 1.9 18.7 122.1 10.5 8.9 297.3 695.6 0.0 7.5 12.1 9.9 46.4 102.4 86.2 12.4 9.7 5.0 442.2 0.0 0.1 31.5 89.5 326.6 146.2 46.0 0.9 232.3 26.6 1.9 533.6 4.3 509.8 1.0 1.0 1.8 45.9 0.4 117.9 12.8 4.5 2.7 137.6 8.1 6.6 6.1 11.2 15.2 14.5 1.9 4.5 11.2 189.9 13.5 21.7 43.4 USHBP1 "AIEBP, FLJ38709, MCC2" ENSG00000130307 "USH1 protein network component harmonin binding protein 1" Q8N6Y0 19 17249171-17282786 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 41.5;Endothelial cells: 28.3;Hepatic stellate cells: 21.4;Ionocytes: 20.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 10.9;HeLa: 5.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA052471 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA052471: AB_2681843" "unprognostic (1.48e-1)" "unprognostic (1.82e-1)" "unprognostic (2.91e-2)" "unprognostic (3.97e-2)" "unprognostic (1.73e-2)" "unprognostic (2.66e-3)" "unprognostic (1.44e-3)" "unprognostic (3.94e-2)" "unprognostic (4.42e-3)" "unprognostic (2.52e-1)" "unprognostic (4.46e-3)" "unprognostic (5.12e-1)" "unprognostic (5.12e-2)" "unprognostic (1.16e-1)" "unprognostic (6.88e-2)" "unprognostic (8.45e-2)" "unprognostic (1.88e-1)" 8.8 1.9 5.0 1.6 4.9 2.9 8.2 7.2 5.2 2.9 4.1 1.9 1.9 3.6 1.1 1.3 3.1 1.7 12.6 5.0 4.1 4.5 1.2 6.9 2.6 4.6 4.5 1.4 4.8 0.8 1.2 5.6 5.1 2.3 0.5 1.1 2.0 0.9 6.2 2.1 2.2 1.3 3.3 3.5 1.7 1.0 5.1 0.5 4.5 4.8 0.5 2.8 2.3 4.6 0.6 0.9 1.7 0.4 0.0 0.0 10.9 0.3 0.0 0.0 0.0 1.9 0.9 2.9 3.4 0.0 0.1 1.2 0.1 0.2 0.0 0.7 1.3 0.7 5.0 1.1 0.0 2.4 2.4 0.3 0.0 0.2 0.2 0.6 3.2 1.1 1.4 1.5 0.0 0.1 0.4 2.4 1.3 0.3 2.7 1.4 0.2 0.7 0.0 1.3 1.1 0.7 0.7 0.7 0.2 0.9 1.3 0.9 1.9 1.8 0.5 1.5 1.0 2.6 0.9 2.8 0.6 1.5 0.6 2.0 0.4 0.7 0.7 0.3 0.6 0.6 0.6 0.7 0.1 1.0 0.9 0.8 1.6 0.7 0.2 0.8 0.8 0.5 5.0 4.9 7.2 5.2 5.0 4.1 4.6 4.5 5.1 3.3 5.1 4.6 41.5 3.2 0.5 0.7 0.0 0.5 0.9 0.1 0.6 0.3 0.5 0.1 6.7 0.0 0.7 0.0 0.0 1.1 3.1 0.2 0.0 0.1 0.7 0.7 0.8 28.3 0.0 0.0 0.4 0.6 0.9 0.9 0.0 1.5 1.3 0.1 21.4 0.3 0.1 0.0 0.5 0.2 20.3 0.6 1.2 0.2 0.6 0.3 5.4 6.5 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.2 1.3 0.1 1.7 0.0 2.2 1.5 0.2 0.4 0.2 1.0 4.5 0.7 0.3 0.0 0.8 USP18 ENSG00000184979 "Ubiquitin specific peptidase 18" Q9UMW8 22 18150170-18177397 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 46.9;Extravillous trophoblasts: 31.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 181.8;BJ hTERT+ SV40 Large T+ RasG12V: 196.2" HPA044768 Uncertain Supported Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol Vesicles "HPA044768: AB_10963697" "unprognostic (2.06e-1)" "unprognostic (3.55e-2)" "unprognostic (1.57e-2)" "unprognostic (5.04e-3)" "unprognostic (1.40e-2)" "unprognostic (5.42e-2)" "unprognostic (3.29e-2)" "unprognostic (5.11e-3)" "unprognostic (1.81e-1)" "unprognostic (1.79e-3)" "unprognostic (9.77e-2)" "unprognostic (1.47e-1)" "unprognostic (4.29e-3)" "unprognostic (2.58e-1)" "unprognostic (2.77e-2)" "unprognostic (2.28e-2)" "unprognostic (8.38e-2)" 10.8 5.0 3.6 5.1 3.8 8.1 8.3 3.3 4.5 4.0 4.0 5.0 6.0 3.2 7.8 4.0 7.3 6.6 4.4 3.7 3.9 5.9 23.6 7.9 9.2 5.1 3.9 2.9 4.2 3.6 5.7 5.7 4.2 5.3 4.4 0.7 14.0 2.5 3.8 3.4 6.7 4.0 7.0 11.0 7.2 9.7 4.1 15.0 7.3 5.5 6.5 4.0 3.6 3.7 14.4 14.6 4.2 18.2 18.2 13.5 18.4 7.3 17.5 181.8 196.2 2.2 20.1 0.2 10.8 4.0 57.5 4.9 21.6 6.4 6.2 64.4 29.4 28.3 1.9 27.0 2.1 6.9 25.7 6.0 2.5 12.8 0.0 1.0 40.8 20.6 1.4 1.7 1.8 24.9 33.4 16.7 12.7 15.6 11.0 13.1 28.4 0.0 3.6 12.4 15.2 11.9 8.8 15.0 71.9 16.3 9.9 6.6 66.7 1.3 3.5 4.1 7.5 3.4 45.4 0.2 16.3 17.1 10.5 3.2 3.9 8.3 8.5 11.0 10.7 5.3 7.2 11.1 1.8 3.4 8.2 9.6 0.7 13.3 8.6 3.3 13.1 5.3 3.6 3.8 3.3 4.5 3.7 3.9 5.1 3.9 4.2 7.0 4.1 3.7 9.7 9.6 4.8 0.7 2.5 1.7 4.5 5.7 2.2 0.2 8.4 8.3 1.4 8.6 6.9 0.0 0.0 4.6 3.0 6.2 46.9 5.9 1.6 20.1 2.5 8.4 3.0 1.3 0.5 11.1 31.9 7.1 4.1 6.3 0.0 8.5 11.0 5.5 8.7 0.0 0.6 3.5 6.1 6.3 0.8 1.7 3.7 3.8 3.6 0.0 1.6 5.1 8.2 2.0 0.3 13.4 3.2 7.2 2.3 2.5 5.4 8.0 12.2 0.3 6.6 8.0 2.5 10.9 1.0 4.0 1.0 1.5 5.0 5.5 2.8 2.9 UST 2OST ENSG00000111962 "Uronyl 2-sulfotransferase" Q9Y2C2 6 148747030-149076990 "Metabolic proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 339.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 15.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "OE19: 32.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032022 Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 68: Oligodendrocytes - Mixed function" "HPA032022: AB_10603326" "unprognostic (3.43e-1)" "unprognostic (1.90e-1)" "unprognostic (7.87e-3)" "unprognostic (3.22e-5)" "unprognostic (1.83e-3)" "unprognostic (1.50e-1)" "unprognostic (5.71e-2)" "unprognostic (1.96e-2)" "unprognostic (8.31e-3)" "unprognostic (2.67e-2)" "unprognostic (3.63e-2)" "unprognostic (1.11e-1)" "unprognostic (9.25e-3)" "unprognostic (9.48e-2)" "unprognostic (1.07e-1)" "unprognostic (2.51e-2)" "unprognostic (3.02e-2)" 6.0 12.2 6.3 3.0 7.4 0.2 6.2 10.0 7.9 7.6 7.5 9.2 1.7 6.8 5.6 4.6 9.2 6.0 4.3 5.8 16.0 3.6 1.3 5.2 3.9 28.2 17.2 11.6 13.1 4.6 1.9 4.6 14.1 6.3 2.7 6.8 3.2 4.8 1.7 6.7 5.7 8.8 13.5 6.5 5.0 6.7 22.7 6.5 27.5 5.8 3.7 8.8 7.7 15.6 0.1 3.2 18.2 14.0 21.5 17.8 0.1 7.9 20.5 3.8 9.8 0.0 1.2 6.7 1.7 12.3 9.5 5.7 13.0 6.6 7.6 9.1 9.9 0.2 10.0 0.1 7.9 0.3 2.8 9.2 14.6 9.8 18.1 7.6 0.2 11.1 0.0 0.0 3.0 8.3 0.1 0.0 10.7 32.4 4.2 3.3 2.5 7.7 0.1 14.8 9.4 0.0 26.4 6.3 5.0 13.0 4.7 0.3 0.4 10.9 1.3 2.5 7.4 0.0 0.0 0.0 12.1 5.4 6.3 0.0 0.0 0.0 0.6 0.2 0.4 0.3 0.4 0.5 0.4 0.5 0.0 0.2 0.0 2.5 0.3 0.4 0.1 0.1 6.3 7.4 10.0 7.9 5.8 16.0 28.2 17.2 14.1 13.5 22.7 15.6 0.9 3.2 3.2 70.2 4.5 9.4 5.4 2.6 3.4 0.1 1.7 1.5 1.7 0.0 2.7 1.8 0.0 2.0 8.9 0.2 0.0 0.1 1.1 0.3 8.7 0.6 0.0 0.0 36.3 2.0 0.3 16.3 7.1 0.4 0.0 12.3 1.4 0.3 1.7 0.0 39.7 1.8 10.2 1.0 20.9 3.4 18.3 2.8 5.4 80.6 1.0 14.6 5.2 339.8 3.2 1.1 0.3 11.3 0.4 5.9 0.0 0.6 2.3 0.8 0.0 6.8 3.5 2.9 5.7 1.9 11.6 1.4 2.0 10.2 0.5 6.8 VAT1L KIAA1576 ENSG00000171724 "Vesicle amine transport 1 like" Q9HCJ6 16 77788564-77980107 "Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "adrenal gland: 70.1;brain: 186.9;choroid plexus: 232.4;retina: 188.7" "Group enriched" "Detected in some" 4 "Horizontal cells: 297.8;Muller glia cells: 106.9" "Cancer enhanced" "Detected in many" "glioma: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 23.1;BJ hTERT+: 68.7;fHDF/TERT166: 38.1;NTERA-2: 79.9;U-87 MG: 82.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044061, CAB046032, HPA061138" Enhanced Approved Cytosol NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 62: Horizontal cells - Visual perception" Cytosol "CAB046032: AB_11126308, HPA044061: AB_10959610, HPA061138: " "unprognostic (1.49e-2)" "unprognostic (8.74e-3)" "unprognostic (8.80e-3)" "unprognostic (3.39e-2)" "unprognostic (3.62e-2)" "unprognostic (1.70e-2)" "unprognostic (2.39e-3)" "unprognostic (1.37e-1)" "unprognostic (1.86e-1)" "unprognostic (7.65e-2)" "unprognostic (8.57e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (3.01e-6)" "unprognostic (2.50e-2)" "unprognostic (6.53e-2)" "unprognostic (1.19e-1)" "unprognostic (5.96e-2)" 1.8 70.1 30.0 3.3 38.1 0.8 0.5 45.7 24.1 0.7 232.4 3.6 2.3 5.4 6.8 1.7 0.9 4.0 15.2 19.6 186.9 5.3 1.0 0.3 0.4 60.2 53.2 0.3 1.8 0.7 4.5 1.9 84.0 0.3 5.6 188.7 1.4 0.4 0.2 0.1 3.2 2.5 49.9 0.0 1.9 1.9 67.4 0.1 2.4 0.3 2.3 1.4 1.2 37.4 0.0 0.0 23.1 0.0 7.8 0.0 0.0 2.8 68.7 0.9 0.7 0.0 0.0 0.0 0.0 38.1 0.7 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.8 0.0 0.5 0.1 1.7 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.4 79.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 3.0 3.7 0.0 1.1 0.0 14.1 0.1 18.6 0.1 0.0 8.6 0.0 0.0 0.0 0.0 0.0 82.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.0 38.1 45.7 24.1 19.6 186.9 60.2 53.2 84.0 49.9 67.4 37.4 0.1 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 7.0 0.1 0.5 9.2 4.3 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.2 4.4 0.0 0.2 0.9 3.0 0.0 20.7 0.0 0.0 1.5 0.0 0.1 0.0 0.1 0.4 0.0 0.2 297.8 31.3 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 1.0 0.6 106.9 0.0 44.7 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.5 0.0 1.8 0.0 0.0 0.3 0.1 0.1 0.0 0.0 VEGFC "VEGF-C, VRP" ENSG00000150630 "Vascular endothelial growth factor C" P49767 4 176683538-176792922 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 39.3;Endothelial cells: 22.0;Leydig cells: 13.7;Microglial cells: 36.5" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 146.5;HBF TERT88: 114.4;hTEC/SVTERT24-B: 116.5;LHCN-M2: 129.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 7.0" "Secreted to blood" NA NA 383000 340000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (4.18e-1)" "unprognostic (4.07e-2)" "unprognostic (4.84e-3)" "unprognostic (1.15e-2)" "unprognostic (2.83e-2)" "unprognostic (3.05e-3)" "unprognostic (1.57e-1)" "prognostic unfavorable (7.88e-5)" "unprognostic (4.53e-1)" "unprognostic (2.80e-2)" "unprognostic (2.23e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (1.89e-3)" "unprognostic (4.41e-2)" "unprognostic (2.54e-1)" "unprognostic (1.22e-1)" 25.0 6.9 2.6 4.2 2.5 0.2 16.7 2.7 2.8 9.7 2.1 4.7 2.4 7.3 1.8 4.0 8.5 6.8 12.7 2.4 2.4 6.7 4.2 16.8 8.0 3.1 2.8 5.9 1.8 2.7 1.5 19.3 2.9 5.1 3.3 1.2 7.4 5.0 3.1 5.1 6.8 6.6 2.6 3.9 3.2 1.4 3.7 1.1 27.7 4.1 3.4 10.3 7.6 2.5 5.9 2.8 1.8 0.0 25.5 25.3 0.0 146.5 87.3 79.2 62.5 0.0 0.7 0.0 0.0 82.7 33.1 4.4 1.3 54.8 114.4 0.1 2.8 0.0 3.8 0.0 13.9 0.0 0.0 27.0 2.5 116.5 80.5 79.3 49.7 0.0 0.0 0.0 129.9 2.1 0.0 0.0 1.3 0.0 47.1 0.0 8.4 0.0 0.0 3.3 0.0 0.0 2.3 3.3 0.1 0.7 0.7 0.2 24.2 83.6 9.2 20.8 42.1 0.2 0.0 0.0 34.9 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.6 2.5 2.7 2.8 2.4 2.4 3.1 2.8 2.9 2.6 3.7 2.5 39.3 3.2 0.0 10.1 0.1 2.4 1.3 3.2 0.0 1.0 3.2 1.7 1.5 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.5 3.1 8.3 10.9 22.0 0.0 0.0 2.0 0.0 0.0 9.1 0.0 11.0 0.0 8.5 10.0 0.0 0.3 1.7 2.0 0.0 4.1 0.3 2.2 1.2 13.7 0.4 3.6 36.5 0.0 3.4 0.0 1.5 0.6 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.4 0.2 0.0 1.9 11.7 0.2 2.0 0.3 2.0 0.0 0.2 1.9 0.0 3.6 VTN VN ENSG00000109072 Vitronectin P04004 17 28367284-28373091 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 61 "liver: 6039.5" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 5507.4" "Cancer enriched" "Detected in many" 85 "liver cancer: 2216.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "CACO-2: 1748.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016695, CAB016765, HPA060933, HPA068011" Supported Supported "Endoplasmic reticulum,Vesicles" "Secreted to blood" NA NA 606000000000 33000000000 "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum, Vesicles" "CAB016695: AB_1624536, CAB016765: , HPA060933: AB_2684389, HPA068011: " "unprognostic (1.19e-1)" "unprognostic (2.12e-1)" "unprognostic (2.29e-2)" "unprognostic (6.13e-2)" "unprognostic (9.74e-2)" "unprognostic (8.42e-2)" "prognostic favorable (3.74e-4)" "unprognostic (6.20e-2)" "unprognostic (3.97e-1)" "unprognostic (8.95e-2)" "unprognostic (3.24e-3)" "unprognostic (1.01e-2)" "prognostic unfavorable (4.10e-11)" "unprognostic (8.82e-3)" "unprognostic (2.27e-1)" "unprognostic (4.86e-3)" "unprognostic (7.09e-2)" 6.2 98.9 2.4 2.5 2.7 0.3 0.9 5.4 3.7 1.0 0.4 0.9 4.6 1.4 0.9 0.5 2.2 61.2 53.1 2.5 2.8 3.6 6039.5 1.8 4.3 2.1 5.3 1.9 17.7 0.1 3.0 40.6 2.3 1.2 0.3 47.4 0.6 4.3 0.4 0.8 1.3 2.7 1.5 2.9 5.1 10.0 2.2 0.1 0.8 0.5 0.4 4.2 0.7 2.4 0.0 28.4 0.7 0.4 0.2 0.3 7.3 1.8 0.8 0.9 0.9 1748.9 0.1 1.2 0.2 0.2 0.2 0.7 0.0 0.0 0.1 0.2 0.2 1.2 1.1 86.7 2.5 6.1 0.5 0.4 0.0 0.6 0.0 3.9 0.1 0.0 1.6 0.3 0.2 0.7 0.2 0.0 0.8 0.4 0.1 0.4 3.5 0.1 0.3 0.0 1.0 1.4 115.6 8.0 0.2 4.3 0.3 0.0 1.0 0.4 0.3 0.1 0.2 1.0 0.5 1.4 0.5 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 2.4 2.7 5.4 3.7 2.5 2.8 2.1 5.3 2.3 1.5 2.2 2.4 0.1 0.0 1.1 2.0 21.5 0.0 0.0 0.0 0.0 13.0 0.1 0.1 18.1 1162.4 0.0 0.0 77.2 3.7 0.0 0.0 3.9 16.8 0.0 0.0 1.2 7.3 0.0 131.0 0.9 19.7 2.8 48.1 0.0 0.0 0.0 1.8 120.3 5507.4 4.7 38.7 1.0 0.1 0.0 160.3 0.3 0.2 0.0 0.3 0.0 0.0 20.1 6.9 0.0 1.0 0.5 23.5 1.2 1.5 0.0 0.0 0.1 9.5 0.0 38.3 0.0 0.4 1.5 4.2 0.6 0.0 0.0 9.6 9.0 0.7 0.0 0.0 WDR17 ENSG00000150627 "WD repeat domain 17" Q8IZU2 4 176065841-176182818 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 11.5;retina: 28.6" "Cell type enhanced" "Detected in many" "Astrocytes: 183.1;Cone photoreceptor cells: 64.6;Excitatory neurons: 222.8;Inhibitory neurons: 127.6;Oligodendrocyte precursor cells: 125.2" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 5.6;SCLC-21H: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042766, HPA054501" Approved Approved "Nuclear speckles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "HPA042766: AB_10806372, HPA054501: AB_2732586" "unprognostic (3.41e-4)" "unprognostic (1.72e-1)" "unprognostic (1.20e-1)" "unprognostic (6.43e-7)" "unprognostic (3.53e-1)" "unprognostic (1.40e-1)" "unprognostic (2.07e-1)" "unprognostic (1.91e-1)" "unprognostic (8.62e-2)" "unprognostic (1.42e-1)" "unprognostic (1.39e-3)" "unprognostic (6.04e-4)" "unprognostic (3.66e-4)" "unprognostic (9.25e-3)" "unprognostic (4.63e-2)" "unprognostic (7.32e-3)" "unprognostic (8.24e-3)" 0.8 2.9 4.5 0.9 7.9 0.6 1.3 2.9 7.6 1.4 0.0 2.5 0.5 1.8 2.4 0.6 1.9 1.1 0.8 8.5 2.5 2.5 0.3 1.4 0.6 0.0 0.0 1.8 2.2 7.0 11.5 0.1 0.8 0.8 1.1 28.6 0.8 0.8 0.2 0.4 1.2 1.0 0.0 1.1 1.3 1.9 2.3 0.3 4.3 0.3 0.5 1.4 1.0 3.4 0.0 2.5 5.6 0.0 0.1 0.4 0.2 0.1 0.0 0.6 1.9 0.2 0.0 3.7 0.0 0.1 3.0 0.0 2.4 1.4 0.5 0.0 2.0 0.0 0.5 0.0 0.2 2.0 2.8 0.8 0.7 0.1 0.3 0.7 0.0 4.3 0.0 0.3 0.5 1.1 2.4 0.1 1.2 0.0 1.4 0.0 2.5 0.0 0.2 0.0 7.6 4.8 0.0 1.4 3.8 0.7 0.4 0.0 0.0 0.8 1.0 0.0 3.4 2.7 1.8 2.3 4.2 0.0 1.4 0.4 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.2 0.0 0.1 0.0 0.0 4.5 7.9 2.9 7.6 8.5 2.5 0.0 0.0 0.8 0.0 2.3 3.4 0.3 0.0 5.8 183.1 2.4 0.1 0.5 0.1 3.4 16.9 0.6 0.9 0.9 1.5 1.3 0.0 64.6 0.0 0.0 0.1 1.9 0.3 1.5 0.5 0.6 0.7 4.8 1.7 222.8 0.6 0.0 2.0 0.0 0.0 3.8 0.1 2.2 0.1 0.2 21.9 127.6 0.1 0.0 0.6 0.6 1.5 0.9 1.3 1.8 23.4 0.6 10.2 0.0 125.2 40.0 0.2 0.0 1.5 0.2 0.4 0.0 11.6 7.7 36.6 0.0 3.0 1.9 2.7 5.2 0.4 0.0 0.0 0.3 1.4 0.1 0.3 WFDC1 PS20 ENSG00000103175 "WAP four-disulfide core domain 1" Q9HC57 16 84294846-84329844 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 99.8;seminal vesicle: 115.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 111.1;Fibroblasts: 72.6;Peritubular cells: 257.3;Smooth muscle cells: 95.8;Theca cells: 325.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 29.8;BJ: 20.5;HEL: 18.2;HeLa: 27.6;THP-1: 9.9;U-937: 10.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031411 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "HPA031411: AB_10600921" "unprognostic (6.53e-2)" "unprognostic (1.27e-1)" "unprognostic (1.61e-2)" "unprognostic (8.66e-4)" "unprognostic (1.41e-2)" "unprognostic (1.50e-3)" "unprognostic (1.47e-2)" "unprognostic (3.11e-2)" "unprognostic (1.60e-1)" "unprognostic (2.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (3.78e-2)" "unprognostic (5.49e-2)" "unprognostic (1.71e-1)" "unprognostic (6.74e-2)" "unprognostic (3.04e-1)" 8.1 26.9 16.5 10.5 16.5 1.9 4.3 19.1 21.2 21.5 12.9 79.3 8.9 17.3 18.8 24.5 7.9 35.1 4.4 16.1 15.5 16.7 5.5 29.5 0.6 17.0 16.2 3.7 1.0 0.4 5.7 99.8 15.3 69.0 17.4 8.4 6.2 115.1 1.2 3.2 14.6 32.2 14.9 3.5 20.8 12.5 16.3 0.3 4.8 1.6 0.8 54.2 13.5 14.9 0.0 0.0 4.4 29.8 0.0 0.1 0.2 20.5 2.5 0.0 0.0 0.0 0.0 0.0 5.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 27.6 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.5 0.0 0.4 0.0 0.0 2.3 0.0 0.0 5.3 0.1 0.0 0.5 3.2 0.1 0.1 9.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.5 16.5 19.1 21.2 16.1 15.5 17.0 16.2 15.3 14.9 16.3 14.9 3.4 3.2 0.5 9.1 0.0 1.8 0.9 0.1 0.0 111.1 2.0 0.9 1.4 0.0 0.1 1.8 0.0 2.1 0.1 0.9 11.7 0.0 27.8 0.6 10.6 3.9 4.2 0.0 4.1 0.0 2.0 72.6 7.7 0.5 0.0 0.2 12.5 0.0 6.6 5.0 0.9 4.7 0.0 0.0 3.0 41.1 15.8 2.3 0.0 2.8 0.0 1.4 0.0 29.1 0.6 0.1 0.6 257.3 0.3 1.3 0.4 1.3 0.7 4.2 0.0 1.0 95.8 5.5 0.9 0.1 0.4 3.8 0.5 325.9 3.1 1.0 WNT2 "INT1L1, IRP" ENSG00000105989 "Wnt family member 2" P09544 7 117275451-117323152 "Cancer-related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "placenta: 39.9" "Cell type enhanced" "Detected in some" "Early spermatids: 30.9;Endometrial stromal cells: 33.1;Fibroblasts: 82.5;Late spermatids: 14.7;Spermatocytes: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-2197: 11.5" "Region enhanced" "Detected in many" "basal ganglia: 12.6" "Low region specificity" "Detected in many" HPA020920 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA020920: AB_1858850" "unprognostic (1.90e-1)" "unprognostic (6.97e-2)" "unprognostic (2.88e-2)" "unprognostic (4.11e-3)" "unprognostic (9.14e-2)" "unprognostic (2.47e-1)" "unprognostic (2.54e-2)" "unprognostic (2.75e-1)" "unprognostic (2.74e-1)" "unprognostic (5.70e-2)" "unprognostic (1.36e-2)" "unprognostic (1.41e-1)" "unprognostic (3.43e-1)" "unprognostic (4.05e-2)" "unprognostic (2.50e-2)" "unprognostic (1.05e-1)" "unprognostic (2.10e-1)" 1.2 0.0 0.2 0.1 0.4 0.0 0.8 0.1 0.7 3.5 0.3 0.1 0.0 8.6 0.1 0.0 0.8 0.2 0.4 0.4 0.3 0.1 0.5 6.9 0.0 0.1 0.5 0.3 0.1 0.0 0.1 39.9 0.1 3.2 0.0 0.0 0.0 0.4 0.0 0.7 0.0 1.1 0.1 0.9 0.0 0.5 1.5 0.0 0.1 0.0 0.0 1.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.8 1.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.7 0.4 0.3 0.1 0.5 0.1 0.1 1.5 0.2 0.5 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.2 0.1 0.3 0.0 1.3 0.0 0.0 3.7 0.0 0.0 0.0 0.0 30.9 0.8 33.1 9.8 0.0 0.0 1.4 0.0 3.6 82.5 0.0 0.6 0.0 0.0 10.8 0.6 7.7 0.0 0.5 0.0 0.0 0.8 0.3 14.7 1.5 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.7 13.6 0.5 0.0 2.7 9.0 0.2 0.0 0.0 0.2 WNT5A hWNT5A ENSG00000114251 "Wnt family member 5A" P41221 3 55465715-55490539 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Wnt signaling pathway" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 27.4;salivary gland: 34.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 51.3;Basal squamous epithelial cells: 34.7;Club cells: 31.3;Endometrial stromal cells: 101.6;Oligodendrocyte precursor cells: 31.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 227.2;BJ hTERT+: 315.4;HeLa: 242.1;SiHa: 354.2;U-87 MG: 248.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "unprognostic (2.34e-3)" "unprognostic (1.35e-1)" "prognostic favorable (2.94e-5)" "unprognostic (1.37e-1)" "unprognostic (3.45e-3)" "unprognostic (1.14e-1)" "unprognostic (2.16e-2)" "unprognostic (3.91e-2)" "unprognostic (5.89e-2)" "unprognostic (9.58e-2)" "unprognostic (8.34e-3)" "unprognostic (1.10e-1)" "unprognostic (4.81e-3)" "unprognostic (9.70e-3)" "unprognostic (2.40e-1)" "unprognostic (5.42e-3)" "unprognostic (3.63e-2)" 2.3 0.8 1.9 3.1 1.9 0.1 4.9 1.7 1.8 5.7 0.6 3.1 3.5 27.4 3.1 16.9 6.7 7.2 1.6 2.5 3.2 2.7 2.6 4.9 2.2 3.9 4.3 9.1 4.3 1.0 1.8 10.8 3.0 4.6 3.2 1.2 34.4 8.3 2.0 2.4 3.8 5.9 3.8 4.0 3.5 1.8 3.1 2.4 2.8 1.7 5.1 18.7 12.1 5.4 0.0 0.4 20.8 0.2 15.8 37.7 0.0 227.2 315.4 46.3 80.4 1.3 0.0 6.6 0.6 132.2 19.5 0.2 10.0 0.2 48.2 0.0 6.2 6.4 242.1 0.1 35.1 0.0 0.4 25.0 5.9 139.2 7.6 22.5 0.1 0.2 0.0 109.5 113.3 0.0 0.1 0.1 11.1 0.5 13.6 0.0 14.1 1.0 6.2 7.6 0.0 1.0 354.2 43.1 0.0 18.0 0.1 0.0 0.0 76.1 13.2 70.0 18.2 25.8 0.0 2.4 248.5 0.3 35.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.9 1.7 1.8 2.5 3.2 3.9 4.3 3.0 3.8 3.1 5.4 1.1 51.3 23.2 4.2 0.0 1.5 1.6 1.4 34.7 13.2 12.1 4.4 4.3 0.0 31.3 12.9 0.0 3.0 0.0 0.2 0.0 0.2 15.8 13.3 101.6 4.3 0.0 0.0 3.0 0.2 0.6 19.9 0.0 13.9 2.5 8.5 1.1 2.6 1.3 0.0 9.0 0.3 10.2 2.4 1.3 4.2 19.6 2.6 0.0 5.6 4.2 1.6 0.0 31.2 0.1 0.4 2.5 30.1 0.1 0.9 2.3 1.0 1.9 1.4 0.0 1.6 7.7 0.1 1.1 17.5 1.6 1.5 1.5 6.5 1.6 9.6 WNT5B ENSG00000111186 "Wnt family member 5B" Q9H1J7 12 1529891-1647212 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 32.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 25.6;Microglial cells: 19.7;Muller glia cells: 40.4;Urothelial cells: 16.2" "Cancer enhanced" "Detected in all" "testis cancer: 15.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8;eosinophil: 1.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 231.4;BJ hTERT+: 143.5;BJ hTERT+ SV40 Large T+: 165.4;BJ hTERT+ SV40 Large T+ RasG12V: 136.4;fHDF/TERT166: 162.6;HBF TERT88: 144.1;hTEC/SVTERT24-B: 144.8;U-138 MG: 142.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA061991 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Vesicles "HPA061991: " "unprognostic (7.44e-2)" "unprognostic (5.59e-2)" "unprognostic (8.14e-2)" "unprognostic (3.69e-2)" "unprognostic (1.12e-1)" "unprognostic (1.45e-1)" "unprognostic (5.53e-3)" "unprognostic (1.26e-1)" "unprognostic (1.10e-1)" "unprognostic (3.02e-2)" "unprognostic (4.08e-2)" "unprognostic (2.16e-2)" "unprognostic (1.49e-3)" "unprognostic (1.90e-1)" "unprognostic (2.93e-2)" "unprognostic (2.77e-1)" "unprognostic (2.71e-2)" 3.0 2.3 3.6 4.1 4.1 0.5 3.0 2.8 3.7 5.5 1.8 24.6 4.3 7.2 5.0 14.9 6.2 2.8 4.0 2.8 5.3 1.9 4.6 3.0 2.6 4.7 3.9 8.2 1.5 9.0 11.2 3.9 4.6 32.4 5.8 5.4 15.7 20.0 1.4 5.3 5.0 5.4 3.9 5.2 6.4 1.8 4.2 3.7 2.0 6.7 3.0 13.9 9.7 3.1 0.3 0.1 1.4 0.2 34.6 61.2 0.0 231.4 143.5 165.4 136.4 8.7 0.9 2.9 0.4 162.6 111.1 3.5 3.3 0.0 144.1 55.0 7.9 12.8 0.0 0.0 8.5 0.2 0.1 51.3 3.3 144.8 41.3 66.6 0.0 0.1 9.5 51.9 39.4 0.1 0.0 0.3 5.7 0.2 0.5 0.0 2.3 4.0 2.0 0.0 1.0 3.2 4.9 0.5 0.2 17.7 0.2 0.9 0.0 142.4 5.9 56.7 119.7 13.9 2.2 0.7 13.9 0.0 1.5 0.0 1.8 1.5 0.0 0.8 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 3.6 4.1 2.8 3.7 2.8 5.3 4.7 3.9 4.6 3.9 4.2 3.1 0.9 0.0 0.6 7.5 1.5 0.9 11.0 1.9 25.6 1.8 0.7 6.5 2.2 0.0 3.3 0.0 0.0 1.0 0.2 2.4 0.0 1.1 0.2 1.7 10.4 1.4 0.0 0.0 6.9 0.7 1.1 8.0 0.5 2.7 0.0 0.3 0.4 1.7 5.3 0.0 7.9 1.9 2.0 2.1 2.9 0.5 2.1 2.7 3.6 19.7 4.1 40.4 0.0 4.0 5.6 2.8 5.0 2.6 4.5 8.8 1.0 0.2 4.3 2.7 6.6 7.9 4.3 0.7 5.7 7.7 1.3 0.7 0.2 0.0 1.7 16.2 YBX2 "Contrin, CSDA3, MSY2" ENSG00000006047 "Y-box binding protein 2" Q9Y2T7 17 7288263-7294639 "Predicted intracellular proteins, Transcription factors" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 77 "testis: 551.1" "Group enriched" "Detected in some" 18 "Early spermatids: 346.9;Late spermatids: 427.3;Spermatocytes: 234.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 4.8;MCF7: 8.7;SH-SY5Y: 3.2;SK-BR-3: 3.9;T-47d: 12.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "CAB012332, HPA053904, HPA056744" Enhanced NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 66: Spermatocytes - Spermatogenesis" "CAB012332: AB_776541, HPA053904: AB_2682302, HPA056744: AB_2683223" "unprognostic (1.76e-2)" "unprognostic (4.62e-3)" "unprognostic (3.99e-2)" "prognostic unfavorable (6.50e-5)" "unprognostic (9.80e-4)" "unprognostic (4.68e-2)" "unprognostic (2.23e-1)" "unprognostic (3.44e-1)" "unprognostic (1.41e-1)" "unprognostic (1.20e-1)" "unprognostic (2.20e-1)" "unprognostic (1.38e-1)" "unprognostic (2.38e-4)" "unprognostic (1.78e-2)" "unprognostic (2.15e-1)" "unprognostic (5.31e-1)" "unprognostic (2.35e-2)" 3.0 0.1 0.5 0.1 0.6 0.2 3.2 0.4 1.1 2.4 0.1 7.2 1.0 1.3 0.0 2.0 2.3 0.0 1.4 0.9 0.5 1.1 1.9 0.1 0.0 0.9 0.7 0.3 0.3 0.3 0.5 0.0 0.6 1.4 0.3 0.0 1.2 0.8 2.0 1.4 4.0 0.5 0.5 0.1 1.2 551.1 0.9 0.0 1.1 0.1 0.0 1.0 0.9 0.8 0.0 0.0 0.0 0.8 0.0 0.0 1.5 0.0 0.0 0.0 0.0 4.8 2.3 0.0 2.4 0.0 0.0 0.4 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 8.7 0.3 0.4 1.5 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.2 1.3 3.9 0.3 2.0 12.6 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.4 1.1 0.9 0.5 0.9 0.7 0.6 0.5 0.9 0.8 0.6 0.0 0.0 0.3 0.0 0.6 0.1 0.1 0.0 0.2 2.8 3.3 4.4 0.0 0.3 1.8 0.0 0.2 0.5 18.0 0.0 0.1 346.9 0.7 0.1 0.7 4.8 0.0 0.5 0.2 0.4 0.4 0.0 0.4 0.0 0.0 0.0 1.5 0.1 0.0 0.1 8.2 0.0 0.0 0.0 427.3 6.8 0.7 3.6 0.0 0.0 0.8 0.0 0.0 0.1 0.0 9.9 6.8 0.0 0.3 10.0 0.4 0.3 0.5 0.0 0.4 1.2 234.3 12.0 1.8 0.9 0.1 0.1 0.1 15.2 1.1 ZMYND12 DKFZp434N2435 ENSG00000066185 "Zinc finger MYND-type containing 12" Q9H0C1 1 42430329-42456253 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 17.1;testis: 28.8" "Cell type enhanced" "Detected in many" "Early spermatids: 164.2;Late spermatids: 71.4;Respiratory ciliated cells: 40.0;Spermatocytes: 95.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 2.6;SK-MEL-30: 2.2;WM-115: 1.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (4.54e-2)" "unprognostic (1.57e-1)" "unprognostic (2.20e-1)" "unprognostic (6.43e-3)" "unprognostic (2.53e-3)" "unprognostic (8.13e-2)" "unprognostic (4.89e-2)" "unprognostic (2.79e-3)" "unprognostic (7.23e-2)" "unprognostic (2.17e-1)" "unprognostic (2.51e-1)" "unprognostic (1.87e-2)" "prognostic favorable (1.11e-5)" "unprognostic (1.76e-1)" "unprognostic (2.27e-2)" "unprognostic (1.52e-1)" "unprognostic (1.45e-1)" 1.0 2.3 4.6 0.2 4.4 0.2 2.2 4.3 5.6 2.0 5.7 1.2 1.0 1.3 9.4 0.3 17.1 1.8 2.3 4.2 5.1 9.3 6.9 1.9 0.4 5.6 7.1 1.9 3.3 2.3 3.4 0.5 5.4 2.3 1.1 4.1 1.0 2.1 1.8 0.7 0.4 0.9 5.0 0.9 1.6 28.8 4.9 0.6 5.0 2.5 0.3 0.9 0.3 5.0 0.0 0.0 0.2 0.8 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.8 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.4 0.0 0.0 0.1 0.0 0.5 0.4 0.0 0.5 2.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.7 0.0 0.0 0.4 1.7 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.7 0.2 0.1 0.0 0.3 4.6 4.4 4.3 5.6 4.2 5.1 5.6 7.1 5.4 5.0 4.9 5.0 0.4 3.2 2.7 4.6 0.5 0.0 0.8 2.6 0.0 0.9 2.5 1.8 3.7 7.2 4.3 7.3 0.0 1.5 0.3 0.6 15.6 1.0 164.2 26.3 1.0 0.5 0.0 1.3 1.6 0.5 1.3 1.3 4.1 1.8 0.0 1.1 0.4 3.8 2.6 0.0 1.7 1.5 6.1 2.6 0.0 71.4 2.5 3.7 3.6 2.8 0.8 3.5 1.0 1.0 1.6 0.1 0.3 2.2 0.8 0.5 0.9 18.4 40.0 2.8 0.0 1.0 0.5 95.9 5.4 0.8 0.3 0.7 0.4 1.9 0.7 1.1 ZNF415 ENSG00000170954 "Zinc finger protein 415" Q09FC8 19 53107879-53133077 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 108.2;Late spermatids: 54.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RT4: 21.9" HPA005553 Approved Approved "Nucleoli fibrillar center,Microtubules" NA NA "Cluster 37: B-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoli fibrillar center, Microtubules" "HPA005553: AB_1859252" "unprognostic (2.15e-1)" "unprognostic (1.34e-1)" "unprognostic (1.83e-1)" "unprognostic (9.31e-2)" "unprognostic (6.30e-2)" "unprognostic (1.29e-3)" "unprognostic (2.18e-1)" "unprognostic (3.24e-2)" "unprognostic (4.05e-2)" "unprognostic (1.15e-1)" "unprognostic (7.28e-3)" "unprognostic (1.51e-1)" "unprognostic (1.06e-2)" "unprognostic (4.27e-2)" "unprognostic (1.28e-1)" "unprognostic (4.38e-2)" "unprognostic (2.84e-2)" 6.7 17.8 14.1 2.0 17.7 0.9 8.5 18.7 18.8 7.5 9.9 7.7 2.0 7.5 13.5 3.4 6.4 5.4 16.7 14.6 16.8 7.0 1.2 4.8 3.2 15.8 15.9 9.5 5.6 11.3 5.3 4.2 16.2 9.7 5.2 10.6 6.2 7.7 4.4 3.9 3.3 7.0 13.2 5.4 5.0 21.6 16.4 4.9 10.8 6.7 2.8 6.4 5.1 27.5 0.2 0.0 4.9 14.2 0.7 0.8 11.3 5.3 8.3 7.6 11.5 9.2 0.3 0.0 2.9 9.2 8.8 0.2 0.0 0.0 7.5 0.0 0.7 0.0 0.5 0.0 2.7 0.0 7.8 8.5 0.1 1.8 0.0 0.8 0.1 0.4 0.3 0.3 4.2 0.7 9.3 0.1 10.3 0.1 0.5 0.0 0.0 0.4 6.3 21.9 3.1 7.6 0.6 0.1 0.0 12.3 7.3 0.4 0.0 3.5 3.4 0.4 6.3 0.2 9.6 6.4 0.4 0.0 11.7 3.6 0.6 3.9 0.3 0.3 0.3 4.1 0.8 0.2 1.2 3.9 1.8 1.6 0.9 3.4 0.5 2.9 0.5 0.6 14.1 17.7 18.7 18.8 14.6 16.8 15.8 15.9 16.2 13.2 16.4 27.5 7.7 0.0 6.2 11.4 2.1 0.5 2.5 0.6 2.8 4.8 4.0 4.7 24.2 1.5 4.4 3.7 2.1 3.5 0.4 1.1 13.7 5.8 108.2 5.0 4.2 6.5 0.0 0.0 9.3 4.7 3.5 4.4 1.5 3.5 0.0 13.3 5.3 0.0 0.7 1.7 13.8 1.9 2.0 0.3 0.9 54.7 1.8 0.5 0.0 2.8 0.6 5.5 7.2 9.5 17.6 2.7 0.3 4.5 0.4 2.5 0.3 0.1 5.4 2.8 0.0 3.0 5.6 17.4 5.0 1.2 0.3 1.9 0.9 17.6 1.3 2.6 ZNF648 FLJ46813 ENSG00000179930 "Zinc finger protein 648" Q5T619 1 182054570-182061712 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.7;Early spermatids: 1.2;Melanocytes: 1.8;Spermatogonia: 1.3;Theca cells: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 78 "HMC-1: 36.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA053897 Uncertain NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA053897: AB_2682297" "unprognostic (3.52e-4)" "unprognostic (1.44e-1)" "unprognostic (7.96e-2)" "unprognostic (1.69e-3)" "unprognostic (2.30e-1)" "unprognostic (4.33e-2)" "unprognostic (1.09e-1)" "unprognostic (1.19e-2)" "unprognostic (2.95e-2)" "unprognostic (2.24e-1)" "unprognostic (1.38e-2)" "unprognostic (8.16e-6)" "unprognostic (4.96e-2)" "unprognostic (3.25e-1)" "unprognostic (2.42e-1)" "unprognostic (2.83e-1)" 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.4 0.0 0.0 0.4 0.4 0.4 0.1 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.8 0.4 0.4 0.5 0.1 1.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 2.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 1.1 0.0 0.0