Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" A2M "CPAMD5, FWP007, S863-7" ENSG00000175899 Alpha-2-macroglobulin P01023 12 9067664-9116229 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 1678.3" "Cell type enhanced" "Detected in many" "Adipocytes: 1319.0;Endothelial cells: 797.7;Hepatic stellate cells: 526.1;Hepatocytes: 910.1;Horizontal cells: 681.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.5" "Lineage enhanced" "Detected in single" "T-cells: 1.5" "Group enriched" "Detected in some" 5 "AF22: 772.0;ASC diff: 223.5;Hep G2: 649.8;SK-MEL-30: 230.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002265, CAB017621" Supported "Secreted to blood" NA NA 1630000000000 170000000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB017621: AB_1118894, HPA002265: AB_1078142" "unprognostic (1.73e-2)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (2.29e-2)" "unprognostic (7.36e-2)" "unprognostic (3.91e-2)" "unprognostic (7.95e-2)" "unprognostic (3.65e-2)" "unprognostic (2.38e-1)" "unprognostic (7.19e-2)" "unprognostic (4.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.28e-2)" "unprognostic (8.04e-3)" "unprognostic (2.32e-2)" "unprognostic (8.58e-2)" "unprognostic (9.03e-3)" 451.5 182.3 157.5 149.8 158.5 5.6 295.3 169.3 223.5 227.2 163.3 257.0 141.2 306.2 244.1 218.3 228.4 452.4 312.8 149.8 175.0 311.4 1250.0 1678.3 98.2 192.9 167.6 101.7 91.5 153.7 135.3 445.2 193.0 293.8 316.3 129.9 131.8 226.7 147.8 71.5 182.7 520.0 196.2 240.6 171.6 58.9 190.7 53.9 202.7 285.6 59.2 847.0 160.2 192.7 0.3 0.0 772.0 0.0 223.5 16.2 2.0 93.1 25.5 0.1 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.3 0.1 0.0 0.0 0.2 0.1 0.4 10.1 649.8 0.0 0.8 0.8 36.9 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.2 0.0 0.0 0.2 2.0 3.3 0.0 0.1 1.8 0.9 0.8 0.0 0.3 0.3 0.7 1.8 0.0 230.1 3.2 0.0 0.3 0.3 0.1 6.7 1.5 0.5 0.7 0.3 0.7 0.2 0.5 15.4 0.0 0.1 0.0 1.5 0.0 0.8 0.0 0.1 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 157.5 158.5 169.3 223.5 149.8 175.0 192.9 167.6 193.0 196.2 190.7 192.7 1319.0 12.8 85.6 5.2 9.0 19.5 2.3 0.0 12.0 5.5 10.8 95.5 106.1 22.8 6.8 1.8 8.4 2.5 8.1 0.0 0.0 0.2 18.8 8.3 54.7 797.7 0.0 45.9 3.2 5.5 2.9 241.3 9.2 14.7 27.8 2.5 526.1 910.1 233.0 681.4 2.9 0.0 0.0 123.1 41.4 36.8 77.3 130.7 23.2 355.1 37.8 6.1 1.0 5.5 4.7 0.2 0.0 141.4 11.2 4.7 0.0 0.3 4.4 21.2 335.2 22.1 328.0 2.7 8.8 8.2 14.1 4.1 13.0 73.3 0.0 3.6 ABCA8 KIAA0822 ENSG00000141338 "ATP binding cassette subfamily A member 8" O94911 17 68867289-68955392 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 231.5;Granulosa cells: 117.3;Leydig cells: 502.6;Microglial cells: 162.1;Oligodendrocytes: 406.6;Skeletal myocytes: 216.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 31.9;ASC TERT1: 69.6;HSkMC: 53.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044914 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA044914: AB_10964859" "unprognostic (2.58e-2)" "unprognostic (2.76e-2)" "unprognostic (1.89e-1)" "unprognostic (1.65e-1)" "unprognostic (3.04e-1)" "unprognostic (6.84e-2)" "unprognostic (1.47e-2)" "unprognostic (1.33e-2)" "unprognostic (1.19e-1)" "unprognostic (5.22e-2)" "unprognostic (6.68e-2)" "unprognostic (8.76e-2)" "unprognostic (1.42e-3)" "unprognostic (3.52e-3)" "unprognostic (1.88e-1)" "unprognostic (3.29e-1)" "unprognostic (6.14e-3)" 39.1 30.5 12.6 2.8 28.1 0.0 21.3 21.0 18.3 10.0 9.6 16.4 6.2 11.9 15.6 7.6 23.7 16.9 42.1 13.6 16.1 9.5 33.7 18.2 1.1 28.2 19.8 51.5 5.7 3.8 11.1 9.0 29.0 9.5 16.9 9.2 14.8 8.6 12.3 6.2 11.8 6.6 20.7 12.4 14.3 19.5 18.4 4.5 17.0 26.7 3.0 16.3 14.6 58.1 0.0 0.0 3.9 0.0 31.9 69.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 12.0 0.0 0.0 53.5 0.0 0.8 0.0 0.4 6.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 28.1 21.0 18.3 13.6 16.1 28.2 19.8 29.0 20.7 18.4 58.1 22.6 51.3 1.1 0.7 0.0 6.0 1.8 0.0 2.8 5.0 0.7 1.0 18.8 0.0 4.3 0.0 2.1 0.2 0.3 0.0 0.0 0.0 4.8 0.4 14.0 6.8 0.0 0.0 0.5 0.0 0.1 231.5 3.1 0.3 1.3 117.3 5.7 48.1 1.1 5.0 0.6 0.0 0.0 1.9 9.4 19.4 502.6 2.6 1.8 162.1 0.0 100.3 0.0 0.5 406.6 0.0 0.0 70.3 1.9 0.4 0.0 0.1 0.0 3.3 39.5 216.6 44.5 5.1 1.7 2.5 4.7 0.3 2.1 60.9 0.0 0.4 ABCB7 "ABC7, ASAT, Atm1p, EST140535" ENSG00000131269 "ATP binding cassette subfamily B member 7" O75027 X 75051048-75156732 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034982 Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA034982: AB_10601010" "unprognostic (1.05e-2)" "unprognostic (1.45e-1)" "unprognostic (1.49e-2)" "unprognostic (1.83e-3)" "unprognostic (4.44e-3)" "unprognostic (1.33e-2)" "unprognostic (6.31e-2)" "unprognostic (4.39e-2)" "unprognostic (1.47e-1)" "unprognostic (2.17e-1)" "unprognostic (4.14e-2)" "unprognostic (2.55e-2)" "prognostic favorable (5.31e-6)" "unprognostic (1.95e-1)" "unprognostic (1.27e-1)" "unprognostic (1.45e-1)" "unprognostic (1.08e-1)" 12.6 13.5 5.0 7.7 5.9 11.1 11.8 8.2 7.6 11.4 9.8 13.8 16.0 10.9 5.0 11.6 11.2 7.4 22.0 5.5 6.1 10.1 14.8 9.8 12.0 6.4 6.0 12.3 9.6 11.0 8.6 7.5 6.2 8.5 9.6 9.8 10.0 6.9 31.4 12.9 11.8 8.8 6.1 10.9 12.3 4.1 5.4 14.0 9.5 22.2 11.1 10.5 10.9 6.8 17.0 16.2 12.2 20.9 14.1 25.5 7.0 8.9 14.6 12.3 22.4 18.5 24.5 25.8 22.8 9.2 21.2 18.8 25.6 18.5 12.0 26.0 33.2 16.8 29.2 17.3 8.2 24.7 13.7 15.9 16.3 12.8 16.7 21.3 23.1 26.2 18.9 31.1 9.8 10.5 24.4 26.1 26.8 26.3 30.5 21.4 26.9 30.5 12.7 13.2 17.7 14.1 27.4 23.5 17.8 20.0 10.2 22.9 10.3 11.3 22.9 23.2 12.4 10.1 27.5 21.2 10.1 35.8 9.4 9.6 26.9 10.0 15.7 25.6 16.6 24.7 16.7 16.7 29.0 28.2 28.7 21.1 2.4 17.5 20.4 18.2 27.2 19.2 5.0 5.9 8.2 7.6 5.5 6.1 6.4 6.0 6.2 6.1 5.4 6.8 12.0 9.6 10.4 48.0 26.6 15.8 14.5 16.0 19.9 10.9 10.9 9.9 46.8 14.3 14.2 11.0 6.2 23.0 19.0 8.2 11.7 17.5 0.4 8.4 12.8 11.9 13.8 26.9 37.9 13.5 11.6 13.9 9.7 10.1 22.2 20.6 9.3 11.8 20.1 25.2 39.0 10.5 8.2 26.1 16.7 0.8 14.6 19.2 10.6 45.0 22.9 12.4 6.2 43.7 46.6 11.6 7.9 13.2 14.3 10.6 15.9 19.9 10.7 7.9 32.9 19.6 13.8 5.5 10.9 16.1 16.1 22.3 14.5 19.2 17.9 11.9 ABCG1 ABC8 ENSG00000160179 "ATP binding cassette subfamily G member 1" P45844 21 42199689-42297244 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 122.6;Syncytiotrophoblasts: 63.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 35.5;neutrophil: 36.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 36.6" "Cell line enhanced" "Detected in many" "hTCEpi: 25.5;JURKAT: 38.4;MCF7: 33.2;MOLT-4: 31.5;OE19: 54.9;RPMI-8226: 25.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031470, HPA031471" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus, Vesicles" "HPA031470: AB_10599188, HPA031471: AB_10600201" "unprognostic (2.89e-2)" "unprognostic (2.53e-2)" "unprognostic (9.96e-2)" "unprognostic (4.20e-3)" "unprognostic (2.87e-1)" "unprognostic (3.09e-2)" "unprognostic (5.74e-2)" "unprognostic (2.07e-1)" "unprognostic (1.54e-1)" "unprognostic (1.66e-3)" "unprognostic (3.66e-3)" "unprognostic (6.37e-2)" "prognostic favorable (7.16e-6)" "unprognostic (1.40e-2)" "unprognostic (2.00e-2)" "unprognostic (1.66e-1)" "unprognostic (2.42e-2)" 17.2 37.7 18.3 12.1 25.5 8.1 15.2 14.4 20.2 8.1 20.0 14.1 17.5 4.9 3.9 4.1 6.3 13.8 10.5 15.5 17.0 10.2 6.3 29.4 18.1 12.0 19.9 6.3 5.3 24.4 10.7 13.7 13.3 6.2 15.0 29.1 16.1 7.0 19.6 16.8 22.0 4.0 12.2 31.2 15.9 1.1 20.3 18.9 8.5 6.2 12.1 12.9 5.0 24.7 0.0 6.0 4.6 2.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 3.1 1.9 0.8 0.0 0.7 0.9 0.0 8.8 0.0 8.5 0.5 10.2 19.2 0.0 17.4 0.0 0.4 2.0 25.5 0.1 3.9 0.0 18.2 38.4 0.0 0.1 0.0 33.2 31.5 0.2 1.4 54.9 10.3 0.4 0.0 25.8 0.0 2.8 22.3 5.8 3.7 13.5 0.0 0.4 5.7 0.9 11.8 0.0 4.7 0.1 0.0 13.1 4.2 0.0 0.1 3.3 0.5 1.7 1.7 35.5 3.0 0.5 5.6 5.5 6.1 6.0 1.1 7.0 5.8 5.0 36.6 7.4 0.3 2.5 7.4 2.1 18.3 25.5 14.4 20.2 15.5 17.0 12.0 19.9 13.3 12.2 20.3 24.7 38.2 6.4 8.2 0.3 21.3 8.9 6.9 3.2 5.7 48.4 4.1 6.9 9.5 4.3 5.9 25.8 50.1 7.0 7.0 33.4 3.9 2.6 4.5 21.6 6.3 33.8 3.5 5.7 13.2 1.2 1.8 7.5 11.2 45.3 0.0 1.2 42.8 0.6 16.0 11.8 17.8 12.1 8.2 44.5 23.4 7.6 0.3 20.9 3.6 7.5 4.3 16.1 3.1 43.2 40.6 2.3 8.3 1.9 4.0 3.0 36.6 1.1 4.5 122.6 6.6 1.6 3.5 0.6 0.5 1.0 6.7 63.1 21.4 10.4 1.1 9.1 ABCG5 STSL ENSG00000138075 "ATP binding cassette subfamily G member 5" Q9H222 2 43812472-43838865 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 69 "intestine: 47.8;liver: 62.0" "Group enriched" "Detected in some" 6 "Hepatocytes: 60.3;Paneth cells: 23.9;Proximal enterocytes: 30.9" "Cancer enriched" "Detected in some" 23 "liver cancer: 11.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 54 "Hep G2: 7.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.71e-1)" "unprognostic (5.47e-2)" "unprognostic (4.01e-1)" "unprognostic (6.92e-2)" "unprognostic (2.24e-1)" "unprognostic (9.97e-2)" "prognostic favorable (2.60e-5)" "unprognostic (4.59e-2)" "unprognostic (3.10e-1)" "unprognostic (1.38e-3)" "unprognostic (3.07e-4)" "unprognostic (1.86e-1)" "unprognostic (3.07e-1)" "unprognostic (5.52e-3)" "unprognostic (8.29e-2)" "unprognostic (5.31e-2)" "unprognostic (3.08e-2)" 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 47.8 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.2 0.0 62.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.1 0.2 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.6 5.7 0.0 0.0 0.0 0.0 0.0 0.2 1.9 0.0 0.0 0.1 0.6 0.1 0.0 0.0 5.5 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.7 60.3 0.0 0.0 3.2 2.5 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 1.8 0.0 23.9 0.0 0.0 0.0 30.9 0.0 0.0 0.7 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.7 0.0 ABCG8 GBD4 ENSG00000143921 "ATP binding cassette subfamily G member 8" Q9H221 2 43831942-43882988 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 40 "intestine: 31.5;liver: 63.4" "Group enriched" "Detected in some" 4 "Hepatocytes: 32.0;Proximal enterocytes: 13.8" "Cancer enriched" "Detected in some" 30 "liver cancer: 21.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 44 "Hep G2: 5.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA019556 Uncertain Approved Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA019556: AB_1844444" "unprognostic (1.99e-1)" "unprognostic (4.49e-1)" "unprognostic (3.22e-1)" "unprognostic (1.37e-1)" "unprognostic (3.09e-2)" "unprognostic (2.43e-1)" "unprognostic (1.99e-3)" "unprognostic (1.27e-1)" "unprognostic (6.28e-1)" "unprognostic (6.14e-3)" "unprognostic (4.69e-1)" "unprognostic (1.76e-1)" "unprognostic (2.68e-1)" "unprognostic (7.86e-3)" "unprognostic (5.03e-1)" "unprognostic (1.50e-1)" 0.1 0.0 0.4 0.1 0.3 0.1 0.0 0.2 1.1 0.0 0.0 0.2 29.8 0.1 0.0 0.0 0.2 0.9 0.0 0.2 0.4 0.3 63.4 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.1 31.5 0.0 0.0 0.1 0.3 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 1.1 0.2 0.4 0.3 0.1 0.4 0.0 0.7 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 2.8 0.6 1.8 0.0 0.0 0.1 0.0 1.9 0.1 0.0 0.2 0.7 0.6 0.0 2.7 3.6 0.0 0.0 0.2 0.0 0.5 0.0 0.2 0.4 32.0 0.0 0.0 2.8 0.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 5.0 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.2 0.0 ACAA2 DSAEC ENSG00000167315 "Acetyl-CoA acyltransferase 2" P42765 18 49782164-49813953 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1011.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 331.1;Hepatocytes: 810.5;Proximal tubular cells: 708.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042303 Approved Supported Mitochondria NA NA 3800000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA042303: AB_10794046" "unprognostic (7.94e-2)" "unprognostic (3.14e-2)" "unprognostic (2.20e-3)" "prognostic unfavorable (8.53e-4)" "unprognostic (2.92e-2)" "unprognostic (2.28e-2)" "unprognostic (7.63e-2)" "unprognostic (1.70e-1)" "unprognostic (7.97e-2)" "unprognostic (8.03e-3)" "unprognostic (1.72e-1)" "unprognostic (3.84e-1)" "prognostic favorable (1.36e-10)" "unprognostic (1.39e-1)" "unprognostic (2.24e-1)" "unprognostic (8.26e-3)" "unprognostic (3.41e-1)" 126.3 74.2 56.9 44.4 64.9 32.5 79.1 63.7 63.9 24.9 68.4 168.7 170.0 29.0 29.8 30.3 24.4 46.9 223.7 53.2 59.8 378.2 1011.9 48.9 36.6 65.1 61.4 34.8 54.1 35.1 34.9 29.6 64.0 26.4 109.6 31.9 20.3 34.0 165.3 28.0 165.2 44.5 62.8 33.6 37.4 37.7 64.3 39.9 55.8 236.6 31.9 41.6 28.6 64.2 3.9 70.5 110.0 97.5 129.9 69.5 57.4 35.2 52.4 53.6 41.2 146.3 58.9 61.1 73.5 117.5 56.7 4.8 176.8 21.0 51.4 190.5 50.4 45.5 79.0 171.4 62.5 0.7 78.3 91.7 6.7 84.8 26.2 44.6 90.0 87.7 42.5 54.7 147.5 81.8 2.7 89.7 101.5 24.8 26.7 150.8 233.0 217.6 177.7 2.8 163.4 130.9 2.7 76.2 5.6 82.1 45.7 60.0 48.1 49.8 60.5 67.8 36.4 112.3 139.7 157.3 35.0 85.7 47.1 53.0 87.4 96.1 99.2 106.5 123.0 43.2 58.3 88.7 103.2 36.3 50.2 73.2 8.3 120.0 108.1 50.1 76.4 112.7 56.9 64.9 63.7 63.9 53.2 59.8 65.1 61.4 64.0 62.8 64.3 64.2 28.4 38.5 47.3 11.8 31.4 3.6 14.2 15.5 11.4 6.7 25.0 25.5 189.9 234.4 23.7 55.2 4.2 36.5 48.2 331.1 295.4 148.5 71.2 7.9 33.9 30.0 40.1 53.6 1.7 45.7 56.0 47.3 23.9 7.7 45.1 63.3 41.4 810.5 109.6 1.7 4.6 73.0 24.4 64.8 18.5 153.9 48.1 50.6 19.6 13.1 57.2 62.2 106.1 4.5 8.7 101.8 161.2 37.2 41.2 9.8 226.6 708.0 26.4 29.5 19.7 42.1 34.9 51.1 42.7 11.1 4.8 27.0 52.2 93.0 144.8 9.6 ACAP1 "CENTB1, KIAA0050" ENSG00000072818 "ArfGAP with coiled-coil, ankyrin repeat and PH domains 1" Q15027 17 7336529-7351477 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.0;intestine: 43.3;lymphoid tissue: 96.0" "Cell type enriched" "Detected in many" 6 "Late spermatids: 3430.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 23.3;HDLM-2: 31.0;JURKAT: 42.4;Karpas-707: 29.4;NB-4: 37.9;U-937: 24.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA075570 Approved Approved "Golgi apparatus" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus" "HPA075570: AB_2732295" "unprognostic (1.20e-2)" "prognostic favorable (3.66e-4)" "unprognostic (2.49e-1)" "prognostic favorable (2.97e-5)" "unprognostic (4.43e-4)" "prognostic favorable (4.17e-5)" "unprognostic (5.66e-3)" "unprognostic (1.11e-2)" "unprognostic (4.67e-2)" "unprognostic (2.48e-2)" "unprognostic (1.42e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.65e-10)" "unprognostic (1.14e-1)" "unprognostic (5.58e-2)" "unprognostic (2.90e-1)" "unprognostic (8.61e-3)" 5.6 1.1 0.4 18.9 0.5 41.0 2.1 0.5 0.8 2.3 0.5 7.4 4.1 1.5 0.3 4.2 4.0 3.6 2.1 0.3 0.4 4.6 5.2 16.1 39.5 0.6 0.5 0.9 1.2 0.1 1.3 0.5 0.6 3.8 2.1 0.2 3.6 0.4 0.9 2.5 43.3 0.9 0.5 96.0 5.0 0.8 0.8 25.8 5.2 0.8 22.6 4.3 3.7 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.1 0.0 23.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.0 8.8 0.1 0.0 0.1 11.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 42.4 0.0 29.4 0.0 0.0 14.5 37.9 0.4 0.0 0.0 15.1 0.2 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.9 0.0 0.0 0.1 0.0 0.0 9.1 8.2 10.9 0.1 24.9 0.0 28.8 7.9 30.8 29.6 2.4 33.3 20.2 31.5 32.1 13.7 21.3 26.7 27.5 22.6 32.5 0.4 17.3 39.0 22.3 0.4 0.5 0.5 0.8 0.3 0.4 0.6 0.5 0.6 0.5 0.8 0.6 3.8 9.6 5.5 1.6 150.9 8.3 7.6 25.1 2.8 15.8 7.0 8.1 32.9 7.2 12.3 5.5 18.8 3.9 160.7 2.0 7.9 3.9 498.1 8.3 5.4 5.0 3.6 22.9 0.3 3.7 3.2 8.0 5.6 3.4 40.5 1.8 7.1 5.3 7.5 0.0 1.9 2.7 8.2 26.2 39.5 3430.7 20.2 27.9 24.9 2.8 38.3 11.7 332.7 0.5 1.0 5.5 0.0 15.4 68.0 4.6 1.3 3.8 44.6 20.4 19.7 7.5 8.1 15.6 10.5 1.5 7.4 4.4 268.3 0.9 1.6 3.5 ACAT2 ENSG00000120437 "Acetyl-CoA acetyltransferase 2" Q9BWD1 6 159762045-159779112 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 231.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 262.1;Early spermatids: 187.0;Exocrine glandular cells: 176.6;Hepatocytes: 214.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021106, HPA025736, HPA025765, HPA025811" Enhanced Approved Nucleoplasm,Cytosol NA NA 14000000 "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol Nucleoplasm "CAB021106: AB_10058215, HPA025736: AB_1844487, HPA025765: AB_1844485, HPA025811: AB_1844488" "unprognostic (3.31e-1)" "unprognostic (2.44e-2)" "prognostic favorable (1.12e-4)" "prognostic unfavorable (7.25e-4)" "unprognostic (1.38e-1)" "unprognostic (2.03e-1)" "unprognostic (9.25e-2)" "unprognostic (4.76e-2)" "unprognostic (1.43e-1)" "unprognostic (2.58e-1)" "unprognostic (1.21e-1)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.38e-4)" "unprognostic (1.39e-1)" "unprognostic (1.50e-2)" "unprognostic (8.56e-2)" "unprognostic (2.54e-2)" 10.9 21.6 22.2 18.5 24.4 22.4 23.6 30.2 30.0 12.8 20.1 38.5 31.2 10.9 40.0 32.6 11.4 10.6 9.4 22.7 27.6 27.0 231.3 20.2 25.0 39.4 26.3 17.3 9.4 12.5 3.2 11.8 39.1 35.6 33.8 19.5 15.5 9.3 4.9 18.1 17.9 15.8 24.8 9.7 19.5 28.6 24.4 39.4 9.0 7.1 36.7 13.7 9.1 28.1 70.1 58.8 451.9 160.8 57.2 111.6 14.4 57.4 70.5 141.8 244.5 234.0 87.1 55.9 29.0 48.7 458.2 64.5 174.8 465.8 166.7 35.2 174.4 127.4 97.2 418.8 62.0 81.4 35.8 62.2 40.1 231.1 92.9 21.4 68.8 160.1 139.9 104.3 85.5 113.0 137.0 154.0 142.8 65.5 41.7 83.9 94.4 173.1 377.2 93.7 107.8 63.2 67.5 43.3 26.2 18.5 83.4 157.3 39.2 50.3 45.7 72.1 154.0 47.7 89.0 142.0 15.7 151.2 77.1 30.1 24.9 46.7 47.9 33.9 47.3 46.6 54.1 47.8 34.7 51.4 53.3 43.2 11.0 41.3 23.6 30.4 79.0 46.2 22.2 24.4 30.2 30.0 22.7 27.6 39.4 26.3 39.1 24.8 24.4 28.1 11.8 12.8 45.4 15.3 25.8 26.1 32.4 262.1 22.2 19.4 33.4 24.5 1.2 42.9 115.5 20.2 2.1 53.7 28.6 34.7 70.5 78.8 187.0 14.3 9.9 18.8 17.2 38.5 14.3 176.6 97.0 21.6 9.7 25.9 13.3 47.7 16.1 214.8 58.1 13.5 14.7 23.6 83.4 14.8 29.8 128.8 13.7 25.7 30.2 1.0 58.9 22.5 30.9 13.0 17.5 65.6 28.8 19.2 25.5 38.7 15.4 50.0 30.1 24.7 0.0 25.1 44.9 28.5 45.6 43.0 21.0 35.2 31.0 102.5 33.0 38.9 ACOT13 "HT012, THEM2" ENSG00000112304 "Acyl-CoA thioesterase 13" Q9NPJ3 6 24667035-24705065 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 30.6" "Cell type enhanced" "Detected in all" "Early spermatids: 847.1;Proximal tubular cells: 525.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019881, HPA057134" Enhanced Approved "Cell Junctions" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 29: Early spermatids - Spermatogenesis" "Cell Junctions" "HPA019881: AB_1857978, HPA057134: " "unprognostic (3.61e-1)" "unprognostic (1.62e-1)" "unprognostic (6.02e-2)" "unprognostic (1.80e-2)" "unprognostic (9.57e-2)" "unprognostic (1.21e-1)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" "unprognostic (1.71e-1)" "prognostic favorable (2.53e-6)" "unprognostic (3.67e-2)" "unprognostic (1.64e-2)" "unprognostic (7.16e-2)" "unprognostic (5.97e-2)" "unprognostic (4.86e-2)" "unprognostic (1.50e-1)" "unprognostic (2.13e-2)" 6.3 6.1 7.2 4.8 7.5 3.4 3.8 7.9 7.3 3.4 6.0 9.1 6.5 3.1 3.7 3.4 3.6 4.9 12.0 6.6 7.8 19.2 30.6 4.6 5.2 7.2 7.8 3.9 6.6 7.2 5.1 3.0 7.4 6.5 7.4 9.6 5.0 3.3 12.2 5.5 6.1 3.1 7.1 4.8 5.5 7.0 8.2 5.1 5.7 10.3 3.4 3.5 3.1 7.4 5.9 7.6 7.6 13.6 10.5 13.1 4.2 4.8 5.8 3.5 5.4 10.1 7.5 11.1 16.2 5.5 18.4 6.4 6.7 9.7 5.4 17.4 6.2 10.4 7.7 7.0 5.3 6.7 4.6 7.6 9.4 4.7 9.0 8.5 8.3 11.3 17.0 5.7 7.0 6.1 12.1 12.9 5.1 11.7 5.9 10.4 6.6 14.0 11.7 5.4 15.0 5.2 5.7 19.1 14.1 8.8 13.2 5.5 9.7 6.2 3.5 1.7 4.6 10.7 29.3 11.1 6.5 23.8 19.1 4.8 5.3 3.6 4.4 5.7 6.1 6.9 4.9 5.0 4.7 4.9 5.7 5.1 6.2 4.6 5.8 3.7 5.3 4.8 7.2 7.5 7.9 7.3 6.6 7.8 7.2 7.8 7.4 7.1 8.2 7.4 27.9 67.3 41.7 19.6 19.7 17.2 26.6 66.4 18.8 18.7 29.4 32.3 94.6 45.8 46.9 31.3 16.7 56.8 22.6 88.4 158.5 43.2 847.1 34.0 31.3 24.0 54.7 37.2 12.1 40.2 31.1 26.2 23.9 31.8 14.5 30.3 21.4 215.5 86.7 5.0 14.3 85.8 67.1 24.5 23.7 131.5 19.6 35.0 26.6 14.0 68.9 41.7 18.6 15.6 18.7 29.2 130.7 24.0 25.4 23.2 47.1 525.2 56.8 31.8 26.3 50.6 64.2 117.1 27.3 19.5 23.4 40.0 20.5 43.4 69.4 28.6 ACOT2 "Mte1, ZAP128" ENSG00000119673 "Acyl-CoA thioesterase 2" P49753 14 73567620-73575658 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 118.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 50.0;Exocrine glandular cells: 33.2;Proximal tubular cells: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 62.4" "HPA043705, HPA060170" Enhanced Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA043705: AB_2678626, HPA060170: AB_2732642" "unprognostic (4.44e-3)" "unprognostic (1.68e-2)" "unprognostic (3.17e-1)" "unprognostic (8.66e-2)" "unprognostic (1.78e-1)" "unprognostic (1.55e-1)" "unprognostic (2.78e-2)" "unprognostic (6.61e-2)" "unprognostic (4.10e-2)" "unprognostic (9.21e-2)" "unprognostic (6.42e-2)" "unprognostic (1.64e-1)" "prognostic favorable (2.28e-6)" "unprognostic (1.66e-3)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (4.35e-1)" 92.3 47.7 10.0 7.0 10.3 5.6 48.9 9.2 12.4 17.1 12.2 42.2 24.7 42.9 10.7 10.9 24.1 6.1 94.5 10.1 9.5 49.4 118.9 17.3 4.7 8.8 9.4 11.7 12.8 22.4 8.3 4.4 8.2 17.8 11.1 4.1 17.8 11.1 114.0 13.1 24.5 22.8 9.2 11.4 22.5 12.0 13.0 3.7 14.5 50.0 3.3 31.2 13.3 9.0 22.8 25.0 4.9 22.1 21.3 7.9 1.0 13.7 31.5 21.9 28.6 18.1 12.6 0.1 9.7 7.0 10.3 12.7 0.0 1.2 11.4 33.1 31.6 16.0 7.6 62.4 14.5 0.1 43.3 19.5 0.0 7.6 0.1 21.0 9.5 0.0 0.0 0.1 18.7 7.4 2.5 18.2 7.5 2.3 37.8 37.2 21.9 0.3 8.0 9.5 21.6 27.3 33.1 24.3 29.6 2.1 51.1 12.7 17.0 17.9 47.2 11.8 13.0 0.0 0.1 9.5 15.8 0.1 18.2 3.5 5.9 3.1 22.1 7.0 15.8 15.0 20.2 16.6 21.9 12.4 17.8 19.9 0.2 15.3 6.5 13.6 31.3 13.6 10.0 10.3 9.2 12.4 10.1 9.5 8.8 9.4 8.2 9.2 13.0 9.0 4.3 0.0 6.4 3.3 6.6 1.7 1.0 5.9 16.5 1.1 5.2 4.2 50.0 7.2 3.0 7.3 10.4 6.1 3.0 20.1 13.7 20.9 1.5 1.4 1.9 4.0 15.7 8.4 2.9 33.2 3.2 7.0 11.7 2.1 13.4 1.9 4.2 27.7 14.9 1.7 3.1 15.5 10.2 3.8 1.6 1.1 5.9 5.6 5.4 1.0 18.5 5.5 7.2 3.0 1.7 21.8 8.6 8.2 7.9 0.4 27.5 36.5 3.3 4.9 6.6 1.4 9.8 0.3 4.8 8.5 0.4 8.2 5.8 1.7 18.8 0.4 ACP1 "HAAP, LMW-PTP, LMWPTP" ENSG00000143727 "Acid phosphatase 1" P24666 2 264140-278283 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 1061.1;Late spermatids: 2128.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA016754 Approved Approved Nucleoplasm,Cytosol NA NA 2000000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 34: Spermatids - Unknown function" Nucleoplasm Cytosol "HPA016754: AB_1844505" "unprognostic (1.15e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-2)" "unprognostic (6.25e-3)" "unprognostic (1.06e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (6.67e-6)" "unprognostic (2.45e-1)" "prognostic unfavorable (3.04e-4)" "unprognostic (9.72e-3)" "unprognostic (4.89e-2)" "unprognostic (2.71e-2)" "unprognostic (7.10e-2)" "unprognostic (2.88e-2)" "unprognostic (3.39e-2)" "unprognostic (1.92e-1)" "unprognostic (2.44e-2)" 41.2 104.0 43.1 45.5 47.6 91.9 64.7 43.9 54.0 43.4 63.9 61.4 64.0 46.6 69.3 43.3 57.9 45.4 57.3 49.4 47.1 78.1 106.4 46.8 66.2 43.4 44.2 59.2 94.1 73.9 59.2 61.7 44.3 52.1 64.7 72.7 71.1 44.2 76.6 41.3 60.7 41.5 44.9 44.7 67.1 46.1 45.3 66.2 63.7 74.9 61.9 47.5 36.4 50.2 78.3 112.5 177.4 97.4 76.1 77.1 142.2 92.6 97.7 91.9 80.8 151.7 78.5 48.8 70.7 85.1 114.6 76.5 169.4 97.0 82.3 118.7 157.9 142.3 99.0 348.5 105.7 162.5 80.4 78.7 90.5 81.9 102.3 95.5 105.8 176.9 145.1 95.1 110.9 103.1 178.5 161.3 214.1 204.7 111.7 118.2 176.1 114.5 144.2 110.5 191.6 191.3 56.0 137.6 196.3 115.0 82.1 89.8 88.9 101.3 65.2 84.0 142.6 123.8 261.2 150.4 120.0 138.9 123.7 65.4 61.6 57.2 88.8 75.2 118.1 106.6 100.4 103.2 57.3 97.2 118.1 115.2 10.9 121.5 80.2 65.3 117.6 115.0 43.1 47.6 43.9 54.0 49.4 47.1 43.4 44.2 44.3 44.9 45.3 50.2 62.5 44.8 96.7 9.1 102.6 79.2 105.3 173.4 51.8 53.1 118.8 130.0 84.9 131.5 119.6 68.0 8.4 207.1 101.3 81.9 270.1 226.7 1061.1 113.1 56.2 70.6 82.5 291.5 20.4 169.0 279.7 74.2 54.6 85.5 70.3 95.9 56.0 115.8 141.1 28.6 21.0 125.1 126.1 72.0 66.3 2128.2 94.4 74.6 81.8 16.9 117.8 92.2 152.4 19.6 26.0 174.4 109.2 92.2 106.4 187.0 174.2 306.6 128.1 56.9 92.1 42.5 87.0 122.6 137.4 87.4 91.2 187.7 86.0 124.4 143.9 148.3 ACP5 "HPAP, TRAP" ENSG00000102575 "Acid phosphatase 5, tartrate resistant" P13686 19 11574660-11579008 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 174.1" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 426.9;Hofbauer cells: 426.7;Macrophages: 298.2;Proximal tubular cells: 145.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 200.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 41.1;K-562: 30.4;RPMI-8226: 41.4;SK-MEL-30: 127.6;U-138 MG: 102.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002584, HPA057655, HPA059463" Enhanced Uncertain Cytosol "Intracellular and membrane" NA NA 4000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB002584: AB_564039, HPA057655: AB_2683490, HPA059463: AB_2684028" "unprognostic (4.27e-2)" "unprognostic (2.05e-2)" "unprognostic (2.93e-1)" "unprognostic (8.60e-3)" "unprognostic (2.96e-1)" "unprognostic (1.95e-2)" "unprognostic (5.21e-2)" "unprognostic (5.17e-3)" "unprognostic (5.13e-2)" "unprognostic (3.80e-1)" "unprognostic (3.66e-3)" "unprognostic (9.09e-2)" "unprognostic (1.39e-2)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "unprognostic (1.05e-1)" "unprognostic (1.19e-1)" 9.4 6.0 2.2 42.4 3.9 9.4 25.6 2.5 21.4 34.7 3.0 46.4 31.9 19.2 7.8 23.4 8.6 26.7 5.1 1.9 3.9 74.0 32.5 174.1 87.1 4.1 3.1 20.3 11.9 2.4 1.3 13.3 6.0 19.6 36.4 20.1 14.3 7.0 1.4 24.9 30.2 13.3 4.1 43.5 38.7 4.0 15.7 25.4 3.0 5.0 43.6 33.1 11.3 5.7 10.2 1.1 0.0 0.2 0.5 0.0 41.1 1.1 25.8 0.0 0.1 0.4 0.3 1.4 1.8 9.0 5.9 0.3 0.0 4.5 0.1 12.1 0.8 0.3 0.0 5.0 1.4 0.1 0.6 0.0 4.1 0.4 0.0 0.0 0.0 0.0 30.4 0.2 0.0 2.3 0.9 1.4 0.8 0.3 0.7 0.4 1.8 41.4 0.0 0.4 0.7 1.0 0.0 0.0 127.6 1.1 0.2 0.4 0.9 102.9 1.2 1.8 0.3 0.7 5.7 0.6 23.7 0.1 4.0 0.4 35.3 76.6 15.8 36.1 8.8 200.1 26.0 19.6 7.3 110.9 35.3 20.2 10.4 13.3 36.3 62.5 67.8 36.4 2.2 3.9 2.5 21.4 1.9 3.9 4.1 3.1 6.0 4.1 15.7 5.7 2.2 9.6 7.8 0.0 75.7 10.3 11.0 21.8 25.0 18.3 14.6 18.4 1.4 15.7 5.7 7.3 18.8 33.4 21.2 7.0 9.8 1.8 0.2 0.7 9.1 30.9 3.0 24.5 0.0 11.3 32.7 19.8 10.7 0.9 63.7 0.8 426.9 8.4 426.7 1.7 0.0 4.7 10.2 106.0 68.6 0.7 1.8 298.2 14.2 1.0 79.8 48.5 8.2 0.0 0.1 4.4 20.4 12.0 33.4 14.5 12.7 145.8 2.5 41.4 0.0 0.4 2.8 0.1 0.2 14.6 11.1 26.1 29.5 0.1 6.7 6.1 ACSL1 "ACS1, FACL1, FACL2, LACS, LACS1, LACS2" ENSG00000151726 "Acyl-CoA synthetase long chain family member 1" P33121 4 184755595-184826818 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 770.4;liver: 1319.0;skeletal muscle: 731.8" "Cell type enhanced" "Detected in many" "Early spermatids: 355.8;Hepatocytes: 1170.0;Late spermatids: 456.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "neutrophil: 475.2" "Lineage enriched" "Detected in all" 9 "granulocytes: 475.2" "Cell line enhanced" "Detected in all" "ASC diff: 1124.0;ASC TERT1: 275.2;HSkMC: 609.5;RPTEC TERT1: 358.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011316, HPA011317, HPA011964" Enhanced Uncertain Vesicles NA NA 44000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA011316: AB_1844536, HPA011317: , HPA011964: AB_1844537" "unprognostic (1.10e-2)" "unprognostic (3.19e-1)" "unprognostic (1.04e-1)" "unprognostic (1.64e-3)" "unprognostic (2.93e-2)" "unprognostic (1.21e-2)" "unprognostic (1.82e-3)" "unprognostic (2.75e-2)" "unprognostic (1.79e-1)" "unprognostic (5.89e-2)" "unprognostic (9.83e-2)" "unprognostic (3.15e-1)" "prognostic favorable (1.25e-5)" "unprognostic (2.77e-1)" "unprognostic (4.38e-2)" "unprognostic (6.25e-3)" "unprognostic (3.13e-2)" 770.4 43.3 32.5 94.8 43.9 337.9 316.7 45.2 70.2 62.1 60.7 34.0 32.4 41.6 78.2 66.0 50.6 36.2 172.7 34.4 39.1 218.7 1319.0 173.7 20.7 63.2 44.4 15.5 49.3 57.0 39.6 30.0 56.2 91.3 16.3 28.4 84.2 30.1 731.8 173.0 34.5 42.8 45.2 132.8 54.2 41.9 63.2 12.2 51.3 442.0 24.7 73.2 57.7 70.8 51.6 15.9 9.7 24.6 1124.0 275.2 8.3 29.1 13.8 16.1 11.2 3.9 14.0 22.2 3.0 32.8 38.4 29.7 43.1 17.8 13.3 107.1 17.7 16.6 13.1 40.5 183.4 41.9 37.2 609.5 140.7 13.6 67.1 27.6 21.1 3.6 7.5 59.4 77.0 26.9 3.1 55.1 2.0 32.5 23.3 8.0 8.6 27.0 358.4 135.9 36.3 35.1 25.4 70.8 86.5 3.9 26.9 39.8 25.1 13.8 16.8 34.5 8.7 24.5 13.5 8.9 45.6 56.3 22.4 16.5 54.7 17.7 3.3 30.9 2.8 3.3 2.3 1.5 13.1 3.4 2.5 2.2 475.2 4.4 23.0 2.4 4.9 20.8 32.5 43.9 45.2 70.2 34.4 39.1 63.2 44.4 56.2 45.2 63.2 70.8 7.5 25.6 121.0 6.5 15.7 21.0 16.0 14.0 5.2 6.6 49.7 10.3 119.1 25.8 33.5 31.3 18.8 10.2 7.1 4.3 93.9 4.6 355.8 9.8 25.0 9.8 0.0 34.1 15.2 12.8 2.2 19.4 36.2 24.6 24.1 1.5 18.2 1170.0 41.8 3.3 22.8 4.7 85.5 140.7 14.6 456.6 19.3 170.1 32.0 6.5 40.5 3.1 1.0 8.5 89.8 8.6 1.6 16.6 8.6 51.3 1.5 111.1 26.8 11.4 13.1 11.1 12.4 10.5 16.7 26.4 41.1 3.4 10.6 1.8 3.2 23.1 ACSM3 "SA, SAH" ENSG00000005187 "Acyl-CoA synthetase medium chain family member 3" Q53FZ2 16 20610243-20797581 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 85.1;liver: 178.5" "Cell type enhanced" "Detected in many" "Granulosa cells: 446.7;Hepatic stellate cells: 100.6;Proximal tubular cells: 136.0;Theca cells: 208.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 23.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 95.1;HMC-1: 381.7;K-562: 285.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041013 Uncertain NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA041013: AB_10671693" "unprognostic (1.62e-4)" "unprognostic (1.30e-2)" "unprognostic (2.12e-2)" "unprognostic (9.50e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (1.42e-2)" "unprognostic (2.20e-1)" "unprognostic (8.14e-3)" "prognostic favorable (1.97e-4)" "unprognostic (3.56e-2)" "unprognostic (1.95e-3)" "prognostic favorable (9.88e-6)" "unprognostic (1.27e-1)" "unprognostic (6.96e-2)" "unprognostic (1.06e-1)" "unprognostic (1.84e-2)" 4.5 3.2 1.7 2.4 1.6 15.3 60.2 2.1 3.1 10.3 1.9 26.4 7.7 19.9 5.7 3.2 26.8 10.4 8.6 1.7 0.8 85.1 178.5 8.1 3.1 3.1 2.7 74.8 30.4 15.2 0.9 2.5 2.5 22.0 25.6 1.0 4.8 6.9 0.8 4.3 8.2 5.1 1.0 1.9 28.1 5.9 2.2 2.8 2.8 1.0 2.9 4.9 5.2 5.3 1.0 12.4 2.3 0.7 3.9 2.3 1.5 0.2 1.3 0.3 1.0 1.0 18.2 1.6 20.1 0.4 0.7 1.6 0.2 2.1 1.6 4.5 6.6 95.1 0.2 7.7 1.3 10.9 381.7 3.7 2.2 0.5 1.4 1.9 0.2 0.7 285.1 15.3 0.1 1.5 0.7 3.5 0.7 14.5 3.8 3.1 0.1 20.3 18.3 1.1 0.8 0.7 0.4 5.4 0.3 0.8 6.1 0.9 1.3 1.2 1.2 0.9 0.7 21.9 18.6 1.2 1.2 7.5 0.5 2.6 2.0 23.5 3.6 1.2 4.2 1.6 4.5 3.3 0.2 2.8 6.9 8.2 0.5 2.3 4.0 2.3 5.6 2.9 1.7 1.6 2.1 3.1 1.7 0.8 3.1 2.7 2.5 1.0 2.2 5.3 0.3 3.2 31.3 1.0 16.5 2.8 34.6 1.5 8.0 0.0 6.3 6.1 3.2 20.0 1.7 12.9 0.0 19.1 1.5 7.0 84.1 84.8 25.0 14.0 4.3 3.4 2.4 25.4 0.3 12.5 2.1 23.7 8.6 32.8 0.0 446.7 100.6 38.2 3.2 0.0 0.3 11.8 0.0 5.4 1.7 12.3 27.7 3.4 0.0 0.0 3.1 0.0 4.1 0.0 0.1 8.9 20.3 12.8 1.0 14.5 4.7 136.0 1.5 0.0 0.0 0.4 52.7 6.9 2.2 3.8 1.8 19.2 4.3 208.3 23.0 11.3 ACTA2 ACTSA ENSG00000107796 "Actin alpha 2, smooth muscle" P62736 10 88935074-88991339 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 6678.8;seminal vesicle: 5920.3;smooth muscle: 8099.9" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 1007.7;Peritubular cells: 5290.7;Sertoli cells: 3030.6;Smooth muscle cells: 2394.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 58.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 390.6;fHDF/TERT166: 641.1;HHSteC: 625.8;HSkMC: 345.1;hTERT-RPE1: 743.4;SuSa: 296.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 101.0" "CAB000002, CAB003761, CAB013531, HPA041264, HPA041271" Enhanced Supported "Actin filaments" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Actin filaments" "CAB000002: AB_2223500, CAB003761: AB_562031, CAB013531: , HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (7.05e-2)" "unprognostic (2.54e-1)" "unprognostic (2.30e-3)" "unprognostic (3.18e-2)" "unprognostic (3.33e-2)" "unprognostic (6.19e-2)" "unprognostic (2.36e-2)" "unprognostic (1.71e-2)" "unprognostic (4.25e-2)" "unprognostic (1.20e-1)" "unprognostic (1.44e-1)" "unprognostic (6.93e-2)" "prognostic unfavorable (1.37e-8)" "unprognostic (1.87e-3)" "unprognostic (2.30e-1)" "unprognostic (7.91e-2)" "unprognostic (2.09e-3)" 1035.2 241.6 54.0 728.1 61.4 3.9 838.4 52.7 121.1 2000.3 61.4 2755.1 248.9 6678.8 1360.1 1509.9 3104.3 906.1 1069.2 53.4 54.6 312.2 161.8 732.8 173.7 59.0 55.9 798.0 91.4 80.6 60.8 771.3 55.3 2642.8 866.4 8.2 414.7 5920.3 202.1 355.7 701.6 8099.9 54.1 452.1 1427.1 263.9 56.1 56.5 312.0 214.0 48.4 3002.5 1367.0 52.9 3.9 19.0 49.3 102.7 198.1 390.6 9.5 109.8 136.8 11.9 45.4 0.0 8.8 7.2 11.5 641.1 8.6 1.4 1.8 25.4 11.3 60.6 11.3 0.4 5.6 119.3 625.8 0.8 3.2 345.1 44.9 73.9 28.5 743.4 11.3 3.0 0.0 7.1 128.8 10.8 1.0 28.3 2.5 0.2 1.2 1.4 0.2 4.6 27.1 5.0 0.7 7.6 10.2 7.9 1.0 296.8 32.4 1.0 27.9 24.0 4.0 30.2 9.3 21.1 1.6 0.6 29.6 10.2 26.1 28.1 12.3 17.5 17.6 8.7 13.8 6.0 14.1 19.8 10.8 1.8 1.5 10.7 11.1 4.0 14.2 0.4 58.7 10.7 54.0 61.4 52.7 121.1 53.4 54.6 59.0 55.9 55.3 54.1 56.1 52.9 65.4 9.6 6.1 5.5 4.4 43.2 23.4 16.5 22.8 1.1 22.7 1007.7 25.1 2.8 5.2 0.0 6.2 16.3 7.3 1.9 1.9 1.8 11.1 11.1 225.4 41.1 0.0 4.0 3.6 0.9 16.8 316.3 10.7 8.2 5.7 448.9 474.0 4.6 37.7 0.0 1.1 2.7 4.1 5.4 67.6 48.8 141.4 12.6 55.2 61.8 4.2 13.4 4.1 1.0 0.3 2.0 3.0 5290.7 3.7 17.5 3.4 9.5 10.9 1.4 3030.6 72.0 2394.6 4.0 13.8 11.1 40.5 23.7 16.5 36.0 5.7 10.4 ACTR3C ARP11 ENSG00000106526 "Actin related protein 3C" Q9C0K3 7 150243916-150323725 "Predicted intracellular proteins" Actin-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "parathyroid gland: 64.1" "Group enriched" "Detected in many" 5 "Astrocytes: 87.1;Excitatory neurons: 111.7;Inhibitory neurons: 125.4;Oligodendrocyte precursor cells: 275.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 31.1;RT4: 26.7;SiHa: 17.8" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (3.41e-1)" "unprognostic (4.79e-2)" "unprognostic (9.62e-2)" "unprognostic (8.25e-2)" "unprognostic (6.07e-6)" "unprognostic (2.83e-1)" "unprognostic (6.81e-2)" "unprognostic (1.19e-1)" "unprognostic (2.10e-2)" "unprognostic (2.91e-1)" "unprognostic (9.69e-3)" "unprognostic (1.65e-2)" "unprognostic (3.27e-2)" "unprognostic (4.73e-3)" "unprognostic (1.72e-1)" "unprognostic (9.14e-2)" "unprognostic (5.53e-3)" 2.2 11.9 3.5 3.4 4.5 1.9 6.2 2.9 3.9 5.2 24.3 5.2 5.2 2.5 7.0 7.1 5.4 4.3 2.0 5.3 3.3 13.2 22.9 5.1 4.1 3.1 3.3 1.5 14.5 64.1 5.3 2.2 3.3 4.3 6.9 4.7 4.8 5.4 1.4 2.6 4.1 2.6 1.9 1.8 4.9 4.1 3.2 2.5 6.0 2.8 5.9 4.9 3.2 2.3 6.7 0.6 0.1 0.2 0.0 0.0 1.1 0.1 0.2 1.1 1.4 5.1 31.1 2.5 8.1 1.2 0.8 13.3 0.0 0.0 0.7 7.1 1.9 1.7 7.5 4.7 3.3 0.0 1.1 1.2 4.2 0.0 0.0 0.8 0.3 3.2 13.2 7.1 0.0 9.4 7.1 0.3 3.5 4.5 0.0 0.0 4.9 10.1 5.1 26.7 6.7 5.4 17.8 3.8 2.7 1.0 8.4 1.6 0.1 0.0 0.0 0.2 0.1 2.5 3.4 0.0 0.2 0.1 0.0 0.3 1.1 2.2 4.9 0.9 2.2 3.4 4.0 3.0 1.7 4.6 4.2 3.4 1.7 3.2 0.5 3.0 3.4 1.3 3.5 4.5 2.9 3.9 5.3 3.3 3.1 3.3 3.3 1.9 3.2 2.3 0.2 3.2 9.5 87.1 3.8 20.1 7.6 5.5 6.8 7.3 4.3 2.4 2.1 7.2 6.4 18.4 29.2 5.6 2.0 7.1 13.7 12.6 4.2 11.7 1.3 1.4 3.5 4.0 111.7 21.3 1.0 1.3 9.7 6.9 11.4 3.4 1.8 20.8 1.2 1.7 125.4 5.1 16.2 1.0 2.8 1.2 0.9 1.2 1.8 9.4 4.6 15.9 7.2 275.5 11.7 11.3 1.3 0.7 6.2 4.8 11.0 14.8 11.1 6.3 0.0 5.0 1.0 6.7 2.8 5.3 14.9 7.1 4.1 2.5 5.7 6.1 ACY1 ENSG00000243989 "Aminoacylase 1" Q03154 3 51983340-51989197 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 9 "intestine: 181.5;kidney: 449.9;liver: 274.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 31.6;Gastric mucus-secreting cells: 32.6;Proximal enterocytes: 144.8;Proximal tubular cells: 92.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 128.0" "CAB003695, HPA036174, HPA036175" Enhanced NA NA 23000000 "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB003695: AB_425286, HPA036174: AB_2674988, HPA036175: AB_2674989" "unprognostic (4.28e-2)" "unprognostic (1.89e-1)" "unprognostic (2.10e-1)" "unprognostic (2.48e-3)" "unprognostic (3.15e-1)" "unprognostic (6.51e-2)" "unprognostic (2.82e-2)" "unprognostic (1.47e-1)" "unprognostic (1.05e-2)" "unprognostic (6.08e-2)" "unprognostic (2.36e-2)" "unprognostic (2.70e-2)" "prognostic favorable (2.93e-4)" "unprognostic (3.57e-1)" "unprognostic (3.75e-1)" "unprognostic (7.88e-2)" "prognostic favorable (6.77e-4)" 19.2 24.0 5.6 7.3 5.7 8.8 20.7 6.4 7.3 13.9 11.6 30.6 181.5 4.3 21.8 10.7 13.0 10.7 14.5 5.1 6.0 449.9 274.9 9.2 7.2 6.5 5.9 4.8 8.7 28.2 4.7 9.7 6.6 14.3 30.5 1.9 16.4 11.1 20.2 8.2 138.2 6.9 6.7 8.1 23.6 3.2 6.1 5.1 21.0 34.6 9.2 12.5 7.1 6.6 15.9 26.2 13.2 34.1 28.9 39.4 40.5 12.6 28.2 29.4 14.9 41.2 67.9 7.2 12.2 22.0 13.2 20.0 14.7 81.2 11.5 21.8 10.7 25.3 13.9 128.0 49.7 19.8 21.0 48.0 67.2 25.4 69.1 25.8 11.5 14.6 47.1 23.9 29.9 35.2 0.6 38.9 23.4 92.1 39.3 8.0 14.1 63.5 74.5 50.8 16.9 18.2 12.6 62.6 29.5 7.5 42.3 27.9 7.1 22.0 21.9 24.8 18.8 61.7 16.9 12.1 28.1 42.9 29.0 9.1 15.7 0.4 10.7 15.1 5.7 7.4 2.6 4.5 21.2 6.1 4.1 4.7 0.0 20.4 6.4 2.8 3.8 9.7 5.6 5.7 6.4 7.3 5.1 6.0 6.5 5.9 6.6 6.7 6.1 6.6 0.5 3.2 3.2 0.0 4.9 0.6 1.0 1.9 17.1 0.2 2.7 1.3 0.2 1.5 2.5 5.5 0.0 3.9 0.3 31.6 9.8 16.6 0.2 0.2 0.9 0.9 2.4 15.8 0.0 8.3 4.5 4.3 32.6 0.6 7.0 0.2 1.1 13.1 1.9 0.0 0.0 11.2 4.1 1.9 0.3 0.8 0.6 4.2 0.0 0.0 9.3 0.8 1.0 0.0 0.0 16.4 23.3 0.0 14.9 0.6 144.8 92.0 1.7 1.1 0.0 0.6 2.0 0.1 0.2 18.5 0.4 4.1 2.6 1.0 14.5 0.4 ACYP2 ENSG00000170634 "Acylphosphatase 2" P14621 2 53970838-54305300 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 207.4;tongue: 163.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 162.6;Excitatory neurons: 158.8;Oligodendrocytes: 180.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035301 Uncertain Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA035301: AB_10670291" "unprognostic (1.19e-1)" "unprognostic (2.84e-2)" "unprognostic (3.40e-1)" "unprognostic (2.16e-1)" "unprognostic (6.90e-3)" "unprognostic (6.21e-2)" "unprognostic (2.03e-3)" "unprognostic (3.17e-1)" "unprognostic (5.22e-2)" "unprognostic (7.83e-3)" "unprognostic (3.64e-3)" "unprognostic (1.16e-1)" "unprognostic (6.66e-2)" "unprognostic (2.13e-1)" "unprognostic (1.97e-1)" "unprognostic (3.24e-1)" "unprognostic (2.24e-2)" 19.5 42.8 64.9 5.4 72.9 7.1 15.7 74.8 85.4 10.6 61.5 14.3 7.4 11.5 12.8 10.4 11.6 8.5 63.4 63.9 72.8 14.5 28.0 10.6 10.9 69.5 68.8 9.3 12.7 13.6 26.2 6.5 70.3 14.4 5.3 24.1 15.2 9.2 207.4 9.9 9.0 7.9 70.4 12.7 12.9 10.2 70.4 10.7 12.6 163.2 8.4 14.0 10.7 76.9 11.7 5.9 6.0 4.4 23.7 17.3 3.7 11.5 9.7 8.3 7.3 1.5 7.1 21.5 33.0 12.6 7.8 8.5 3.3 10.8 7.4 14.4 13.1 13.4 6.3 16.3 8.5 12.7 6.3 13.6 19.3 5.6 9.5 15.2 3.9 9.8 5.5 11.5 17.9 7.6 7.5 17.0 5.9 8.4 6.7 5.4 4.7 12.2 18.8 10.6 17.6 10.0 17.4 10.0 5.7 1.9 3.4 13.2 10.9 11.5 10.6 3.5 11.1 21.4 12.5 10.2 16.3 24.3 12.4 41.2 14.0 26.1 16.9 13.0 15.4 29.0 16.6 16.1 20.3 26.9 20.1 16.4 11.5 18.6 13.5 33.4 16.3 11.3 64.9 72.9 74.8 85.4 63.9 72.8 69.5 68.8 70.3 70.4 70.4 76.9 21.7 16.0 17.9 84.9 30.6 20.5 41.9 52.8 18.8 15.5 49.7 65.7 162.6 34.3 32.0 18.4 10.4 13.6 27.9 24.5 62.6 24.3 86.8 29.5 23.6 23.1 30.6 14.5 158.8 38.1 6.1 21.0 26.0 19.5 19.7 17.6 30.7 74.2 31.9 28.6 134.1 21.9 36.7 40.0 28.5 64.7 13.4 25.4 23.2 59.0 26.1 90.1 24.7 67.8 180.1 29.9 18.8 30.9 36.4 27.4 29.1 55.6 32.2 31.6 52.6 30.8 30.0 22.9 9.8 28.9 21.3 10.3 22.7 29.7 18.6 45.0 ADAM33 "C20orf153, dJ964F7.1, DKFZp434K0521" ENSG00000149451 "ADAM metallopeptidase domain 33" Q9BZ11 20 3667965-3682246 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 280.4" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 40.8;Fibroblasts: 45.2;Leydig cells: 22.7;Microglial cells: 18.7;Smooth muscle cells: 17.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 82.4;ASC TERT1: 104.9;BJ: 38.5;BJ hTERT+: 64.7;fHDF/TERT166: 38.9;U-2197: 50.9" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Low region specificity" "Detected in all" "HPA067152, HPA071758" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear speckles" "HPA067152: AB_2685791, HPA071758: " "unprognostic (1.10e-1)" "unprognostic (3.02e-2)" "unprognostic (2.24e-2)" "unprognostic (3.35e-3)" "unprognostic (4.39e-3)" "unprognostic (7.43e-4)" "unprognostic (7.14e-3)" "unprognostic (1.67e-1)" "unprognostic (1.78e-3)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (3.56e-1)" "unprognostic (2.75e-11)" "unprognostic (1.05e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-5)" "unprognostic (3.10e-3)" 53.3 3.8 7.8 10.5 8.5 0.1 47.4 5.8 12.3 280.4 8.4 157.2 11.0 151.8 19.0 31.6 106.9 32.8 26.7 6.7 9.3 3.9 2.0 18.0 6.2 16.0 8.0 58.7 6.0 0.5 6.9 12.7 16.4 87.0 12.1 1.0 19.6 57.5 9.1 22.0 43.4 53.0 5.9 8.3 44.8 22.5 6.9 0.9 18.4 14.1 2.2 125.4 159.0 6.2 0.0 0.0 0.2 0.0 82.4 104.9 0.2 38.5 64.7 11.2 21.3 0.1 0.0 0.0 0.2 38.9 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.1 0.0 13.0 0.0 0.0 18.2 0.0 4.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 2.8 0.2 2.9 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.1 0.1 0.0 0.2 0.0 50.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.8 8.5 5.8 12.3 6.7 9.3 16.0 8.0 16.4 5.9 6.9 6.2 3.9 0.0 0.0 7.2 0.1 5.5 0.1 0.0 0.6 0.0 0.3 0.3 3.3 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.5 1.8 40.8 2.4 0.0 0.0 1.3 0.0 0.1 45.2 2.6 1.2 0.0 3.1 1.8 0.0 0.5 0.0 11.4 0.0 0.0 0.3 8.8 0.8 22.7 0.8 3.6 18.7 0.0 2.2 0.0 8.0 0.1 0.0 0.0 10.1 0.0 0.2 0.0 0.9 0.0 0.1 6.6 6.8 17.1 0.7 0.5 0.3 3.1 0.5 0.7 0.0 0.0 0.1 ADAMTS12 ENSG00000151388 "ADAM metallopeptidase with thrombospondin type 1 motif 12" P58397 5 33523535-33892019 "Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 25.2;Fibroblasts: 22.9;Leydig cells: 22.1;Microglial cells: 73.1;Sertoli cells: 52.6;Theca cells: 55.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 47.4;hTERT-RPE1: 88.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA035973, HPA075079" Uncertain Approved Nucleoli,Mitochondria "Secreted to extracellular matrix" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 52: Non-specific - Transcription" Nucleoli Mitochondria "HPA035973: AB_10669663, HPA075079: AB_2732278" "unprognostic (6.18e-3)" "unprognostic (3.12e-4)" "unprognostic (1.05e-1)" "unprognostic (8.37e-2)" "unprognostic (1.65e-1)" "unprognostic (3.52e-1)" "unprognostic (2.60e-2)" "unprognostic (3.49e-3)" "unprognostic (3.78e-3)" "unprognostic (3.39e-2)" "unprognostic (5.63e-3)" "unprognostic (1.45e-1)" "unprognostic (4.27e-7)" "unprognostic (4.45e-3)" "unprognostic (1.47e-1)" "unprognostic (5.85e-2)" "prognostic unfavorable (6.78e-4)" 9.0 5.2 0.9 1.6 0.7 0.0 7.8 0.5 0.4 2.7 1.7 2.5 0.5 3.8 0.5 0.9 3.2 4.0 1.6 0.2 0.4 1.3 1.4 5.6 0.9 1.2 0.9 2.7 0.6 0.5 0.6 3.9 1.0 1.3 1.0 0.7 0.9 1.4 0.8 1.5 1.1 6.5 1.5 0.5 1.2 2.0 1.3 0.3 1.9 0.7 0.6 2.2 2.0 3.3 28.7 0.9 25.5 0.0 35.9 17.2 0.0 13.3 33.1 16.8 19.5 0.0 0.0 0.0 0.0 9.0 29.1 0.8 0.7 16.7 24.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 13.8 0.0 47.4 12.2 88.0 0.0 0.0 0.0 0.1 26.6 0.0 0.0 0.0 5.0 0.0 0.0 0.0 29.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 36.9 0.0 0.0 0.0 28.0 36.2 0.3 7.9 4.4 3.5 0.0 23.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.5 0.4 0.2 0.4 1.2 0.9 1.0 1.5 1.3 3.3 6.4 0.0 0.0 1.3 0.5 0.8 0.0 0.0 0.0 0.1 1.5 2.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 4.9 1.2 25.2 2.1 0.0 0.0 3.0 0.2 0.4 22.9 0.0 0.6 0.0 3.3 11.4 0.2 0.6 0.0 6.2 0.0 0.0 0.3 2.1 3.0 22.1 0.2 7.2 73.1 0.0 5.3 0.0 0.5 7.8 0.1 0.0 17.7 0.0 0.1 0.0 2.4 0.7 0.2 52.6 1.7 19.1 0.4 4.7 0.1 0.9 0.8 0.3 55.4 0.0 0.1 ADAMTS13 "C9orf8, DKFZp434C2322, FLJ42993, MGC118899, MGC118900, TTP, vWF-CP, VWFCP" ENSG00000160323 "ADAM metallopeptidase with thrombospondin type 1 motif 13" Q76LX8 9 133414358-133459402 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 63.8" "Cell type enhanced" "Detected in many" "Astrocytes: 16.0;Early spermatids: 19.3;Excitatory neurons: 12.4;Inhibitory neurons: 12.4;Late spermatids: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042014, HPA042844, HPA052077" Approved Approved Vesicles "Secreted to blood" NA NA 1300000000 120000000 "Cluster 34: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA042014: AB_2677798, HPA042844: AB_2678200, HPA052077: " "unprognostic (1.09e-1)" "unprognostic (1.45e-1)" "unprognostic (8.75e-4)" "unprognostic (1.49e-2)" "unprognostic (1.83e-1)" "unprognostic (3.02e-1)" "unprognostic (4.76e-2)" "unprognostic (2.54e-1)" "unprognostic (2.33e-2)" "unprognostic (1.88e-1)" "unprognostic (4.52e-5)" "unprognostic (1.11e-1)" "unprognostic (9.91e-2)" "unprognostic (4.78e-2)" "unprognostic (3.57e-1)" "unprognostic (1.82e-2)" "unprognostic (2.30e-3)" 2.5 2.8 6.9 0.5 7.3 0.6 2.8 7.6 10.0 5.0 5.3 4.3 3.2 4.2 2.9 2.4 5.7 1.2 6.0 7.1 6.2 9.6 63.8 2.8 0.9 7.0 6.7 6.7 6.2 1.5 12.5 0.8 7.1 6.4 0.9 1.1 2.5 1.4 4.3 2.6 4.4 0.6 6.3 2.6 9.8 13.5 7.2 0.8 6.1 1.4 0.5 4.4 3.1 7.1 0.0 0.8 1.9 2.6 1.5 1.3 0.8 0.7 0.5 0.2 0.3 0.3 2.1 0.2 0.9 0.4 0.6 0.3 0.1 0.4 0.1 1.2 1.7 0.2 0.9 0.4 1.1 0.0 0.7 3.6 0.9 0.2 0.7 1.2 0.1 1.3 0.0 0.8 0.3 3.3 0.0 0.9 2.0 1.1 1.1 0.2 0.2 0.9 0.8 0.8 1.3 4.0 1.4 0.6 1.2 3.9 3.7 0.4 0.5 1.5 0.8 0.9 0.0 1.7 0.3 0.3 1.1 0.2 1.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 7.3 7.6 10.0 7.1 6.2 7.0 6.7 7.1 6.3 7.2 7.1 0.9 0.0 2.0 16.0 1.2 0.3 0.3 0.9 0.0 1.7 1.4 1.9 4.2 4.3 2.4 0.0 0.0 0.2 0.2 1.0 1.9 0.6 19.3 3.6 1.6 0.9 1.2 0.0 12.4 0.4 0.3 1.5 4.6 3.3 0.0 3.0 5.0 1.6 0.2 3.3 12.4 1.3 0.0 0.6 0.0 13.6 0.9 0.3 0.0 7.5 0.0 1.7 0.0 2.0 5.5 0.3 3.0 1.5 0.4 0.4 1.5 0.9 0.7 1.8 0.0 0.4 0.7 6.0 3.9 0.3 0.4 0.1 0.5 1.7 0.9 0.3 ADAMTSL2 KIAA0605 ENSG00000197859 "ADAMTS like 2" Q86TH1 9 133532164-133575519 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 73.2;liver: 35.8" "Cell type enhanced" "Detected in some" "Distal tubular cells: 5.9;Endothelial cells: 5.7;Fibroblasts: 8.5;Microglial cells: 12.2;Sertoli cells: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 7.4;RPMI-8226: 10.1;SH-SY5Y: 30.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045634, HPA053812" Approved Approved Vesicles "Secreted in other tissues" NA NA 170000000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA045634: AB_2679399, HPA053812: AB_2682271" "unprognostic (5.10e-2)" "unprognostic (1.50e-2)" "prognostic unfavorable (5.01e-4)" "unprognostic (8.35e-2)" "unprognostic (1.07e-1)" "unprognostic (5.50e-2)" "unprognostic (6.78e-3)" "unprognostic (1.31e-2)" "unprognostic (5.49e-2)" "unprognostic (1.35e-1)" "prognostic favorable (6.70e-4)" "unprognostic (5.17e-2)" "unprognostic (7.37e-2)" "unprognostic (1.56e-1)" "unprognostic (3.40e-1)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" 3.7 28.5 6.8 1.0 7.3 0.1 1.5 12.0 10.1 2.3 1.4 2.7 1.4 3.1 3.1 1.8 3.1 2.5 73.2 5.8 7.9 25.9 35.8 23.2 3.4 19.3 11.1 4.9 7.1 1.2 15.9 1.5 20.8 8.4 0.3 0.3 3.4 2.2 4.3 0.8 3.2 0.9 8.5 6.4 2.3 3.1 9.3 0.6 12.1 0.5 0.6 5.3 1.6 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.6 0.5 0.0 1.1 0.7 10.1 0.0 0.0 1.4 30.1 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 7.3 12.0 10.1 5.8 7.9 19.3 11.1 20.8 8.5 9.3 7.6 1.4 0.0 0.5 4.9 0.1 0.1 0.1 0.0 0.0 4.2 0.0 0.1 2.3 0.0 0.0 1.8 0.0 0.1 0.0 1.4 5.9 0.2 0.1 0.1 0.1 5.7 5.3 0.0 5.0 0.0 0.1 8.5 0.0 0.0 0.0 0.1 4.6 0.9 0.3 0.0 3.8 0.4 0.0 0.3 0.8 1.1 4.7 0.6 0.0 12.2 0.0 0.4 0.0 2.5 4.0 0.2 0.5 3.0 0.0 0.2 0.0 0.7 0.0 0.2 6.6 1.1 1.6 0.1 0.8 0.4 0.3 0.0 0.6 0.7 1.1 0.2 ADAMTSL3 "KIAA1233, punctin-2" ENSG00000156218 "ADAMTS like 3" P82987 15 83654088-84039842 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 141.1;Alveolar cells type 2: 111.8;Astrocytes: 86.5;Club cells: 61.7;granulocytes: 63.1;Inhibitory neurons: 91.6;Oligodendrocytes: 75.2;Respiratory ciliated cells: 56.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "EFO-21: 12.1;hTERT-RPE1: 3.6;RPTEC TERT1: 14.0;TIME: 13.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034773, HPA034774" Uncertain Uncertain Vesicles "Secreted in other tissues" NA NA 270000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA034773: AB_10601965, HPA034774: AB_2674326" "unprognostic (2.20e-1)" "unprognostic (1.37e-1)" "unprognostic (2.98e-2)" "unprognostic (1.07e-2)" "unprognostic (1.56e-1)" "unprognostic (9.89e-2)" "unprognostic (4.07e-2)" "unprognostic (3.27e-1)" "unprognostic (9.18e-3)" "unprognostic (5.92e-2)" "unprognostic (9.97e-2)" "unprognostic (3.85e-1)" "unprognostic (8.59e-3)" "unprognostic (5.00e-3)" "unprognostic (4.62e-1)" "unprognostic (8.64e-2)" "unprognostic (3.95e-5)" 6.3 4.2 1.1 1.0 1.7 0.0 1.7 1.4 1.0 3.1 4.4 10.6 1.4 6.9 1.5 3.3 4.4 1.1 10.7 1.1 1.1 3.3 10.4 7.4 1.1 1.4 1.5 1.2 7.3 0.8 1.4 10.4 1.7 6.6 3.2 0.3 2.4 7.1 2.6 1.4 1.8 4.7 1.5 1.9 4.6 2.7 1.1 1.0 2.6 4.8 0.5 5.2 2.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.9 0.0 14.0 0.0 0.0 0.0 0.2 0.2 0.0 1.3 0.0 0.0 13.3 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.7 1.4 1.0 1.1 1.1 1.4 1.5 1.7 1.5 1.1 3.0 8.7 141.1 111.8 86.5 0.1 7.0 5.2 1.7 0.6 0.2 0.2 0.3 9.4 0.0 61.7 1.8 0.0 0.1 0.8 0.0 0.0 0.5 14.9 0.6 0.4 10.6 0.0 0.0 31.3 2.4 0.2 29.0 1.5 1.2 63.1 0.1 1.1 10.2 0.2 6.7 91.6 0.0 0.0 0.6 0.5 16.9 49.4 5.9 0.0 5.6 0.0 0.1 1.0 4.5 75.2 1.0 0.0 17.0 0.4 2.4 0.0 0.6 56.4 0.2 26.3 13.0 8.3 2.1 2.8 0.6 1.1 0.1 5.0 0.4 0.0 2.3 ADARB1 "ADAR2, ADAR2a, ADAR2a-L1, ADAR2a-L2, ADAR2a-L3, ADAR2b, ADAR2c, ADAR2d, ADAR2g, DRABA2, DRADA2, hRED1, RED1" ENSG00000197381 "Adenosine deaminase RNA specific B1" P78563 21 45073853-45226560 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, mRNA processing" "Hydrolase, RNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 62.9;Excitatory neurons: 54.1;Horizontal cells: 69.0;Inhibitory neurons: 85.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 65.8;HHSteC: 65.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029645 Supported Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "HPA029645: AB_10602106" "unprognostic (2.69e-1)" "unprognostic (7.65e-2)" "prognostic unfavorable (8.16e-5)" "unprognostic (1.82e-2)" "unprognostic (1.07e-2)" "unprognostic (9.07e-2)" "unprognostic (3.29e-2)" "unprognostic (6.97e-2)" "unprognostic (3.82e-2)" "unprognostic (1.23e-2)" "unprognostic (1.28e-1)" "unprognostic (3.44e-1)" "prognostic unfavorable (3.56e-4)" "unprognostic (4.57e-2)" "unprognostic (3.06e-1)" "unprognostic (2.73e-2)" "unprognostic (2.38e-2)" 15.4 7.0 14.9 10.3 13.2 5.2 11.4 39.1 26.5 14.7 29.6 35.7 3.0 23.0 6.3 7.4 13.6 8.1 10.1 20.0 17.9 9.5 7.0 35.2 13.4 30.6 17.2 7.8 6.1 9.3 6.1 12.3 30.8 17.9 4.8 28.6 6.8 8.1 13.6 15.9 10.8 11.7 8.7 16.1 19.0 4.5 22.7 5.7 6.6 11.8 8.7 60.4 11.9 12.7 7.0 1.0 5.3 6.2 6.3 4.3 7.2 4.6 7.6 14.4 9.0 10.9 1.1 2.2 12.1 22.6 7.9 0.6 7.8 19.1 15.9 1.7 7.0 15.2 65.8 7.2 65.7 10.5 7.2 23.7 8.1 5.1 14.9 5.4 15.4 20.4 3.5 0.8 42.2 5.1 6.8 10.0 8.6 3.4 10.1 2.0 5.0 7.1 3.2 2.3 30.6 8.2 36.4 1.6 11.6 8.5 3.5 8.2 16.3 4.7 5.7 19.4 17.5 6.6 3.1 1.8 4.3 24.1 25.8 0.7 0.0 2.4 0.4 0.2 0.8 1.0 1.1 0.7 0.0 2.6 0.7 0.6 0.1 0.3 0.2 1.0 0.8 0.2 14.9 13.2 39.1 26.5 20.0 17.9 30.6 17.2 30.8 8.7 22.7 12.7 29.0 0.0 1.1 10.7 12.0 11.1 2.9 3.4 2.8 62.9 6.2 7.1 21.6 1.5 1.9 0.0 12.5 0.5 5.9 0.9 0.0 1.3 2.7 1.6 8.8 21.2 0.0 2.1 54.1 0.5 1.2 9.4 2.6 1.6 8.2 5.5 14.3 6.3 5.9 69.0 85.7 0.9 0.0 3.4 4.9 2.9 3.7 3.2 5.4 37.5 5.0 34.2 2.1 16.1 4.8 1.0 0.1 5.7 4.0 5.5 0.3 2.7 0.7 16.0 0.0 32.9 12.7 11.4 17.7 1.5 7.2 1.0 13.7 1.4 1.2 2.3 ADGRA2 "DKFZp434C211, DKFZp434J0911, FLJ14390, GPR124, KIAA1531, TEM5" ENSG00000020181 "Adhesion G protein-coupled receptor A2" Q96PE1 8 37784191-37844896 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Wnt signaling pathway" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 30.6;Endometrial stromal cells: 49.4;Fibroblasts: 36.4;Hepatic stellate cells: 31.4;Leydig cells: 56.5;Microglial cells: 24.4;Muller glia cells: 25.0;Peritubular cells: 41.8;Sertoli cells: 46.0;Smooth muscle cells: 36.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 83.6;ASC TERT1: 64.8;BJ hTERT+: 75.2;fHDF/TERT166: 77.6;HSkMC: 39.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012393 Uncertain NA NA 270000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA012393: AB_1849256" "unprognostic (1.63e-1)" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (1.21e-1)" "unprognostic (2.00e-1)" "unprognostic (6.34e-2)" "unprognostic (1.38e-1)" "unprognostic (3.75e-2)" "unprognostic (1.15e-2)" "unprognostic (1.20e-2)" "unprognostic (3.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.18e-7)" "unprognostic (2.65e-2)" "unprognostic (4.90e-2)" "unprognostic (6.12e-2)" "unprognostic (4.60e-3)" 29.1 4.8 10.0 12.2 8.6 2.0 26.4 8.7 10.1 59.8 5.9 24.1 7.7 45.1 18.2 24.8 43.8 26.2 17.6 9.8 6.5 9.6 4.3 16.2 7.7 7.7 8.3 35.9 5.5 2.2 10.0 48.7 7.8 44.4 8.2 6.7 9.0 54.9 6.6 13.1 12.8 27.8 7.0 11.9 12.3 3.5 11.2 5.2 11.3 8.3 5.6 39.6 32.0 6.6 0.2 2.3 0.3 4.7 83.6 64.8 0.6 38.5 75.2 4.6 12.4 0.5 0.2 0.0 6.9 77.6 3.1 0.9 3.5 0.2 1.5 1.6 1.8 0.2 2.2 0.2 38.1 0.0 0.0 39.4 0.4 3.4 0.8 3.3 22.3 3.0 0.2 0.7 1.2 1.2 0.1 8.0 3.5 0.0 0.6 6.5 4.2 0.4 0.0 0.1 0.3 18.1 1.0 0.2 5.7 17.7 0.2 16.9 18.2 7.6 9.6 11.2 3.5 6.2 0.5 0.1 1.0 20.3 8.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 8.6 8.7 10.1 9.8 6.5 7.7 8.3 7.8 7.0 11.2 6.6 30.6 0.0 0.0 1.0 0.2 0.0 0.1 0.0 0.0 1.0 1.0 1.1 1.3 0.0 0.0 0.0 0.0 1.1 0.2 0.0 1.9 0.1 0.2 1.5 49.4 17.8 0.0 0.0 7.8 1.6 0.6 36.4 0.0 2.2 0.0 0.1 31.4 0.1 2.1 0.0 7.8 0.2 0.0 1.6 0.0 3.1 56.5 1.5 0.0 24.4 1.0 25.0 1.0 3.0 0.8 0.3 0.1 41.8 0.1 0.3 0.0 0.0 0.0 0.7 46.0 5.5 36.0 0.3 0.8 0.5 0.0 2.3 0.4 2.6 0.3 0.2 ADGRF5 "DKFZp564O1923, GPR116, KIAA0758" ENSG00000069122 "Adhesion G protein-coupled receptor F5" Q8IZF2 6 46852522-46954943 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 104.5" "Cell type enhanced" "Detected in many" "Adipocytes: 428.1;Alveolar cells type 1: 291.7;Alveolar cells type 2: 539.9;Endothelial cells: 222.6;Hepatic stellate cells: 251.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 25.0;TIME: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 55000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (8.45e-2)" "unprognostic (3.00e-3)" "unprognostic (1.13e-1)" "unprognostic (3.26e-1)" "unprognostic (6.51e-2)" "unprognostic (1.89e-2)" "unprognostic (5.76e-2)" "unprognostic (9.00e-3)" "unprognostic (7.80e-2)" "unprognostic (3.32e-1)" "unprognostic (1.42e-1)" "unprognostic (4.56e-2)" "prognostic favorable (8.84e-5)" "unprognostic (1.43e-2)" "unprognostic (5.91e-2)" "unprognostic (2.82e-2)" "unprognostic (3.78e-2)" 69.8 22.8 15.1 6.9 15.0 0.0 46.0 15.0 18.0 10.4 8.6 9.9 5.7 16.0 7.7 7.0 15.0 16.9 51.6 12.8 15.1 58.9 13.0 104.5 8.5 16.6 15.6 6.5 6.4 13.2 6.7 50.6 18.2 8.9 5.7 1.8 5.9 9.2 30.4 7.7 8.5 21.8 13.8 40.5 8.4 3.1 21.6 3.7 32.2 70.2 3.2 11.4 10.0 15.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 74.1 0.0 0.2 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 15.0 15.0 18.0 12.8 15.1 16.6 15.6 18.2 13.8 21.6 15.3 428.1 291.7 539.9 2.0 2.9 0.0 0.2 0.0 2.2 0.0 1.5 2.9 16.2 8.6 89.7 1.8 0.0 0.2 1.1 0.6 11.7 0.2 10.6 0.8 1.2 222.6 0.0 0.0 8.4 0.0 1.1 9.0 2.6 0.4 12.6 0.0 251.3 4.0 0.2 0.0 1.0 0.5 0.0 13.7 0.0 4.8 3.1 2.7 0.0 104.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 1.2 0.6 0.5 0.2 48.1 0.7 98.6 9.6 80.1 0.2 0.9 0.6 0.0 0.3 1.8 15.5 0.1 0.8 ADGRL3 "KIAA0768, LEC3, LPHN3" ENSG00000150471 "Adhesion G protein-coupled receptor L3" Q9HAR2 4 61201258-62078335 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.3" "Group enriched" "Detected in many" 11 "Astrocytes: 584.1;Excitatory neurons: 696.1;Inhibitory neurons: 737.4;Oligodendrocyte precursor cells: 1300.8;Oligodendrocytes: 592.1" "Cancer enriched" "Detected in some" 9 "glioma: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 41.8;EFO-21: 10.8;HEK 293: 6.5;SuSa: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015027, HPA015762, CAB022698" Uncertain NA NA "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "CAB022698: , HPA015027: AB_1853243, HPA015762: AB_1853245" "unprognostic (2.88e-2)" "unprognostic (1.12e-1)" "unprognostic (6.43e-4)" "unprognostic (1.79e-2)" "unprognostic (1.88e-1)" "unprognostic (7.56e-2)" "unprognostic (8.70e-2)" "unprognostic (5.42e-2)" "unprognostic (1.62e-2)" "unprognostic (1.28e-1)" "unprognostic (6.81e-2)" "unprognostic (1.28e-1)" "unprognostic (1.62e-5)" "unprognostic (1.03e-2)" "unprognostic (1.44e-1)" "unprognostic (9.85e-3)" "unprognostic (4.23e-3)" 7.1 6.2 25.1 1.1 25.7 0.0 2.5 14.0 30.7 5.5 0.0 4.0 2.5 3.9 1.8 1.0 2.4 1.6 2.6 30.4 25.0 1.6 0.4 2.6 0.4 15.3 24.6 1.1 0.3 6.7 0.9 1.2 15.9 1.3 3.9 10.0 0.6 4.2 0.7 3.0 3.6 3.0 12.5 0.3 3.2 4.1 32.3 0.4 0.7 0.3 0.1 1.6 3.4 15.7 0.0 0.1 41.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 10.8 0.0 0.0 0.0 5.9 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.1 0.0 3.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 1.0 0.0 4.0 0.5 0.1 0.1 0.0 4.8 0.2 0.0 6.3 0.3 0.0 0.0 0.0 7.6 0.1 3.2 0.0 0.2 4.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.1 25.7 14.0 30.7 30.4 25.0 15.3 24.6 15.9 12.5 32.3 15.7 0.4 0.0 0.0 584.1 0.0 0.0 0.0 0.0 0.6 12.4 4.9 1.8 3.3 0.0 0.0 0.0 4.2 1.0 0.0 0.0 9.8 0.0 46.4 1.3 17.7 1.9 0.0 0.0 696.1 0.0 1.3 3.3 0.0 0.4 0.0 0.4 2.5 0.2 0.1 1.7 737.4 0.0 0.0 0.0 0.0 33.2 0.0 0.5 0.0 70.3 0.0 31.3 0.0 1300.8 592.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 2.4 6.6 0.3 18.5 0.9 3.5 1.2 0.0 2.2 0.2 0.1 0.0 0.1 ADGRL4 "ELTD1, ETL" ENSG00000162618 "Adhesion G protein-coupled receptor L4" Q9HBW9 1 78889764-79282124 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 73.1" "Group enriched" "Detected in many" 5 "Adipocytes: 559.9;Endothelial cells: 276.0;Hepatic stellate cells: 287.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "hTERT-RPE1: 101.2;HUVEC TERT2: 330.0;TIME: 379.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025229 Supported NA NA 3800000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA025229: AB_10602493" "unprognostic (2.67e-1)" "unprognostic (2.17e-1)" "unprognostic (2.05e-2)" "unprognostic (2.58e-1)" "unprognostic (5.32e-2)" "unprognostic (8.11e-3)" "unprognostic (2.01e-1)" "unprognostic (1.23e-1)" "unprognostic (7.52e-2)" "unprognostic (2.38e-1)" "unprognostic (2.57e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (5.32e-3)" "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (3.85e-3)" 73.1 8.2 7.7 9.7 8.2 0.7 64.0 8.5 13.8 22.1 7.0 9.3 4.7 16.3 6.2 9.0 12.1 22.4 24.2 8.0 8.0 15.2 14.3 18.0 9.9 9.1 7.7 4.8 4.7 9.7 5.1 22.5 9.1 9.4 6.3 3.0 7.9 8.9 14.2 9.0 8.6 27.6 7.6 39.8 8.0 6.7 9.8 4.6 20.8 23.6 7.1 24.0 10.4 8.4 0.0 0.0 25.7 0.2 7.3 24.7 0.0 7.8 7.7 0.5 0.3 0.8 0.2 0.2 0.6 22.5 0.0 0.0 0.1 0.0 5.0 0.0 0.0 0.5 0.7 0.1 25.3 0.0 0.3 17.8 0.4 55.7 0.3 101.2 330.0 0.2 0.4 2.5 7.0 0.0 0.0 1.0 0.4 0.2 0.4 0.2 0.0 0.0 61.1 3.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 379.3 0.2 5.8 2.0 0.0 0.8 0.5 0.1 0.3 0.5 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 7.7 8.2 8.5 13.8 8.0 8.0 9.1 7.7 9.1 7.6 9.8 8.4 559.9 0.0 6.0 0.3 1.2 0.0 0.4 0.0 4.6 0.0 1.8 2.5 7.6 5.7 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.2 45.3 0.8 1.5 276.0 0.0 2.7 1.5 0.2 0.0 10.2 0.0 3.8 0.0 0.0 287.7 3.5 0.6 1.7 1.0 0.0 0.0 19.2 0.0 57.9 0.6 1.5 0.0 72.1 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.4 1.2 1.3 0.0 0.0 0.0 0.4 0.0 5.1 5.7 7.2 1.8 1.0 0.0 0.0 1.1 5.4 0.0 0.7 ADH7 ADH-4 ENSG00000196344 "Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide" P40394 4 99412261-99435737 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 196.3" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 89.0;Club cells: 64.1;Squamous epithelial cells: 209.1" "Cancer enhanced" "Detected in some" "cervical cancer: 18.4;head and neck cancer: 18.9;lung cancer: 22.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC TERT1: 1.0;HaCaT: 1.2" "Not detected" "Not detected" HPA039695 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "HPA039695: AB_10795681" "unprognostic (1.02e-2)" "unprognostic (8.64e-2)" "unprognostic (4.86e-2)" "unprognostic (5.66e-3)" "unprognostic (4.50e-2)" "unprognostic (1.66e-1)" "unprognostic (2.02e-1)" "unprognostic (1.88e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 196.3 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 27.3 0.0 0.0 0.2 0.0 0.0 38.1 0.3 4.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 89.0 21.1 0.0 0.0 0.0 0.2 0.0 64.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.1 7.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 18.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.6 0.0 0.0 26.2 0.0 0.0 0.0 2.3 0.0 0.0 209.1 0.0 0.0 0.0 0.0 0.0 1.0 ADHFE1 FLJ32430 ENSG00000147576 "Alcohol dehydrogenase iron containing 1" Q8IWW8 8 66432492-66468907 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 31.2;skeletal muscle: 29.2;tongue: 31.3" "Cell type enhanced" "Detected in many" "Astrocytes: 76.4;Cardiomyocytes: 41.6;Syncytiotrophoblasts: 116.4" "Cancer enhanced" "Detected in many" "liver cancer: 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.2;RPTEC TERT1: 1.5" "Low region specificity" "Detected in all" HPA023062 Enhanced Approved Vesicles NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA023062: AB_1844611" "prognostic favorable (5.76e-5)" "unprognostic (8.69e-2)" "unprognostic (6.71e-2)" "unprognostic (2.70e-1)" "unprognostic (1.14e-1)" "unprognostic (1.22e-1)" "prognostic favorable (9.90e-5)" "unprognostic (7.76e-3)" "unprognostic (2.88e-1)" "unprognostic (1.32e-1)" "unprognostic (1.59e-1)" "unprognostic (9.43e-2)" "prognostic favorable (4.55e-5)" "unprognostic (1.37e-2)" "unprognostic (2.06e-1)" "unprognostic (4.66e-2)" "unprognostic (5.94e-3)" 7.0 2.3 8.7 0.3 8.5 0.0 3.9 7.2 11.7 2.3 10.4 3.9 0.6 2.0 1.3 1.3 5.6 0.7 24.5 8.2 8.2 6.6 31.2 2.1 0.3 8.3 8.5 5.1 9.4 5.0 2.6 1.1 8.1 5.2 0.7 1.5 2.3 1.5 29.2 1.1 2.5 0.2 7.8 1.8 11.0 1.7 8.7 0.3 2.7 31.3 0.3 4.4 1.8 8.5 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.2 0.0 0.2 0.0 0.5 0.1 0.0 0.3 0.0 0.4 0.1 0.3 0.0 0.7 0.0 0.0 0.0 0.0 8.7 8.5 7.2 11.7 8.2 8.2 8.3 8.5 8.1 7.8 8.7 8.5 1.5 9.6 20.1 76.4 1.8 1.0 4.1 2.7 3.4 1.7 4.6 4.6 41.6 14.3 9.6 9.2 10.4 8.8 6.5 1.0 11.7 1.5 0.5 2.5 1.6 3.3 3.6 2.5 8.3 0.6 0.9 5.3 8.6 2.5 8.8 6.1 6.1 27.1 2.5 0.0 13.2 2.0 4.1 2.1 2.8 1.6 23.9 2.1 0.0 14.0 2.0 7.6 6.2 21.6 19.2 0.9 5.8 27.1 3.0 3.5 4.1 14.8 14.3 8.5 0.0 7.8 5.2 0.5 0.6 1.9 1.0 116.4 10.0 2.5 2.4 2.5 ADORA3 AD026 ENSG00000282608 "Adenosine A3 receptor" P0DMS8 1 111499429-111503633 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.8" "Cell type enhanced" "Detected in some" "Hofbauer cells: 17.9;Kupffer cells: 79.2;Late spermatids: 18.2;Macrophages: 26.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 40 "eosinophil: 601.6" "Lineage enriched" "Detected in many" 40 "granulocytes: 601.6" "Cell line enriched" "Detected in some" 9 "HMC-1: 108.1" "Low region specificity" "Detected in many" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" 4.5 15.0 8.9 4.3 9.2 0.2 5.5 10.6 14.6 4.4 8.8 6.6 4.5 1.9 0.2 2.5 3.6 5.8 3.4 8.8 12.3 1.6 3.3 3.5 6.4 16.1 11.1 1.8 1.8 3.1 2.6 2.8 14.9 2.4 5.1 1.0 2.8 2.4 0.5 0.9 9.4 4.8 13.5 4.3 3.0 1.2 16.9 3.5 1.4 1.0 2.7 4.3 1.7 21.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.8 0.0 0.0 0.0 0.0 108.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.0 8.1 601.6 0.0 5.6 0.1 0.2 0.0 0.0 15.0 0.1 0.1 0.1 2.0 0.1 2.1 3.0 0.0 2.5 8.9 9.2 10.6 14.6 8.8 12.3 16.1 11.1 14.9 13.5 16.9 21.8 0.2 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.1 0.1 0.6 0.4 0.0 0.0 0.0 0.0 0.1 1.4 0.1 0.0 0.0 7.3 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.0 0.0 1.8 0.2 17.9 0.0 0.0 0.0 0.0 79.2 4.4 18.2 0.3 26.3 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.2 0.2 0.4 0.3 0.1 0.4 0.0 1.6 0.0 0.0 0.1 AFG3L2 "SCA28, SPAX5" ENSG00000141385 "AFG3 like matrix AAA peptidase subunit 2" Q9Y4W6 18 12328944-12377227 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004479, HPA004480" Enhanced Supported Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA004479: AB_1078109, HPA004480: AB_1078108" "unprognostic (1.11e-1)" "unprognostic (7.49e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (1.31e-1)" "unprognostic (5.06e-3)" "unprognostic (1.61e-1)" "unprognostic (2.33e-1)" "unprognostic (5.35e-2)" "unprognostic (1.54e-2)" "unprognostic (4.05e-2)" "unprognostic (3.00e-2)" "prognostic favorable (6.05e-14)" "unprognostic (5.90e-2)" "unprognostic (9.41e-2)" "unprognostic (5.74e-3)" "unprognostic (2.22e-1)" 26.1 25.9 16.4 21.9 17.0 32.4 29.2 18.2 19.0 24.1 30.8 60.8 79.9 22.1 17.5 41.5 23.8 18.3 88.0 17.0 18.7 62.7 51.0 21.8 23.7 17.7 16.6 24.1 41.1 76.0 18.6 23.5 18.8 24.6 54.1 20.3 30.8 24.4 145.4 29.8 58.7 25.4 15.8 18.5 39.1 18.5 19.0 24.3 39.2 155.8 31.0 30.9 19.6 17.6 56.5 56.6 39.7 44.8 45.2 48.6 52.7 61.9 61.1 86.6 63.1 88.1 34.1 161.3 66.3 56.6 76.8 55.6 101.4 71.3 70.3 38.1 43.5 48.5 59.3 83.5 61.1 185.0 69.8 54.3 76.3 82.1 107.7 47.8 64.0 57.0 111.3 92.8 43.6 89.0 66.7 58.5 55.3 277.4 41.9 74.0 125.1 135.2 74.9 123.6 73.7 51.3 97.0 103.8 90.0 50.5 47.8 84.5 49.0 102.4 88.6 98.7 81.7 64.7 80.7 104.1 56.2 71.4 48.0 3.8 16.5 12.4 11.6 17.6 13.9 14.0 13.8 17.9 21.8 10.3 17.2 20.2 1.1 28.4 16.2 11.5 9.5 13.4 16.4 17.0 18.2 19.0 17.0 18.7 17.7 16.6 18.8 15.8 19.0 17.6 24.3 41.7 49.2 23.2 36.6 22.2 45.3 21.5 42.7 50.2 36.5 36.2 74.9 50.1 28.1 35.0 50.1 58.5 29.1 85.2 72.4 39.5 5.5 37.8 52.3 27.7 39.1 61.0 21.1 37.4 37.9 31.2 53.5 46.1 14.5 41.3 21.8 85.6 37.0 30.3 26.8 82.6 18.3 32.6 14.4 5.5 32.9 34.2 23.2 12.2 27.6 26.9 40.2 14.1 17.7 47.8 43.1 30.1 38.8 43.1 88.7 100.0 22.1 58.3 26.3 53.6 26.9 50.9 65.0 75.8 31.3 92.8 28.4 60.8 94.9 38.2 AGAP1 "CENTG2, GGAP1, KIAA1099" ENSG00000157985 "ArfGAP with GTPase domain, ankyrin repeat and PH domain 1" Q9UPQ3 2 235494043-236131800 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 53.9;retina: 54.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 304.0;Cone photoreceptor cells: 329.4;Excitatory neurons: 289.3;Oligodendrocyte precursor cells: 1438.1;Oligodendrocytes: 997.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.2" "Lineage enriched" "Detected in single" 13 "T-cells: 1.2" "Cell line enhanced" "Detected in many" "SCLC-21H: 78.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 68: Oligodendrocytes - Mixed function" "unprognostic (1.69e-1)" "unprognostic (2.32e-2)" "unprognostic (3.42e-1)" "unprognostic (5.43e-2)" "unprognostic (1.19e-1)" "unprognostic (4.80e-2)" "prognostic unfavorable (2.60e-5)" "unprognostic (1.36e-1)" "unprognostic (6.91e-2)" "prognostic unfavorable (9.75e-4)" "unprognostic (1.46e-1)" "unprognostic (2.10e-1)" "prognostic favorable (6.52e-5)" "unprognostic (5.56e-2)" "unprognostic (2.44e-2)" "unprognostic (6.32e-2)" "unprognostic (1.32e-2)" 5.3 4.7 30.7 3.4 34.4 1.9 8.3 7.6 29.6 5.7 0.0 12.5 7.0 5.2 8.9 6.6 6.7 5.6 5.9 34.0 33.0 7.7 2.6 5.6 1.7 44.6 24.1 5.5 6.5 8.9 7.1 6.9 48.2 4.8 11.2 54.7 4.2 5.0 8.4 3.7 8.6 10.5 10.9 1.9 6.7 6.6 30.5 1.5 9.1 9.2 1.9 6.2 3.4 53.9 17.3 13.6 20.9 9.8 15.1 9.7 13.1 8.6 9.1 9.9 7.5 14.0 31.3 0.1 3.6 14.9 37.2 4.3 15.8 20.4 12.3 0.3 8.1 26.4 12.5 10.5 6.0 0.1 17.5 14.1 19.3 20.4 15.9 7.1 6.8 6.1 13.8 1.0 12.6 22.2 0.5 3.0 9.1 14.9 6.2 3.6 10.6 16.8 10.8 20.4 78.9 19.9 7.3 17.1 9.5 11.4 9.8 4.1 6.8 11.8 12.0 9.8 11.7 5.4 0.1 0.8 18.4 0.2 12.7 0.0 0.0 0.0 0.6 0.0 1.2 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 30.7 34.4 7.6 29.6 34.0 33.0 44.6 24.1 48.2 10.9 30.5 53.9 16.0 6.4 15.5 100.6 0.2 4.1 3.7 6.2 5.2 304.0 19.4 11.7 22.9 2.8 8.7 11.0 329.4 9.7 5.5 23.3 3.9 21.4 9.4 24.0 12.0 13.3 16.3 0.4 289.3 15.0 1.5 19.5 4.6 15.8 20.8 12.7 7.9 6.3 1.4 119.5 219.0 17.8 12.2 0.6 3.8 2.9 5.0 2.1 1.8 139.6 1.6 33.3 9.2 1438.1 997.9 19.1 20.7 13.5 0.8 4.9 21.1 14.0 14.4 142.0 26.3 20.4 22.5 4.8 20.7 7.1 4.3 6.6 3.0 7.0 21.8 4.9 AGBL2 "CCP2, FLJ23598" ENSG00000165923 "ATP/GTP binding protein like 2" Q5U5Z8 11 47659591-47715389 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 7.7;testis: 12.5" "Cell type enhanced" "Detected in many" "Early spermatids: 37.5;Endometrial ciliated cells: 25.7;Respiratory ciliated cells: 77.2;Spermatocytes: 19.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.3;T-47d: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007718 Uncertain NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "HPA007718: AB_1078110" "unprognostic (3.44e-5)" "unprognostic (1.16e-1)" "unprognostic (5.84e-2)" "unprognostic (5.33e-4)" "unprognostic (1.13e-1)" "unprognostic (3.00e-1)" "unprognostic (2.05e-1)" "unprognostic (1.38e-2)" "unprognostic (9.83e-3)" "unprognostic (4.11e-2)" "unprognostic (5.56e-2)" "unprognostic (1.79e-1)" "unprognostic (8.24e-6)" "unprognostic (1.01e-2)" "unprognostic (1.28e-1)" "unprognostic (9.62e-2)" "unprognostic (1.17e-3)" 0.3 1.3 0.3 0.4 0.2 0.2 0.5 0.7 0.3 1.4 2.6 0.8 0.3 0.6 1.1 0.4 7.7 0.2 0.2 0.3 0.4 1.6 3.0 1.6 0.5 1.2 1.8 1.3 0.8 0.3 1.7 0.2 0.8 1.2 0.2 0.3 0.5 0.4 0.0 0.4 1.2 0.1 1.0 0.9 0.6 12.5 0.2 0.7 1.5 0.0 0.4 1.1 0.6 0.4 0.4 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.3 0.2 0.6 0.2 2.3 0.0 0.1 0.1 0.2 0.6 0.0 0.0 0.3 0.7 0.1 0.1 1.1 0.8 0.3 0.0 0.3 0.6 0.2 0.3 0.2 0.2 0.0 0.8 0.1 0.5 0.3 0.9 0.5 0.2 0.0 0.1 0.0 0.6 0.0 0.2 0.3 1.0 0.8 0.1 0.2 0.0 0.2 0.0 1.3 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.2 0.3 0.3 0.0 0.5 0.4 0.4 0.1 0.3 0.0 0.3 0.5 0.1 0.3 0.2 0.7 0.3 0.3 0.4 1.2 1.8 0.8 1.0 0.2 0.4 0.1 0.0 2.7 2.6 1.3 0.1 1.3 2.6 2.2 0.1 0.9 0.6 0.6 0.0 6.5 7.3 0.0 0.4 0.5 0.7 0.0 0.4 37.5 25.7 1.3 0.1 1.2 0.8 0.6 0.0 0.3 1.2 1.5 0.9 0.0 0.8 0.4 0.8 0.1 0.0 0.6 0.5 2.0 0.6 0.0 8.2 0.3 0.3 0.0 1.0 1.0 0.7 0.0 1.0 0.5 0.3 0.6 1.5 0.4 0.4 2.4 0.2 77.2 0.5 0.0 0.3 1.1 19.3 1.8 0.6 0.0 0.4 1.3 1.3 0.9 0.5 AGT SERPINA8 ENSG00000135744 Angiotensinogen P01019 1 230690776-230745576 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 1603.7" "Group enriched" "Detected in many" 9 "Cholangiocytes: 985.1;Hepatocytes: 2244.9" "Cancer enriched" "Detected in all" 4 "liver cancer: 1163.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Hep G2: 646.2;THP-1: 243.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025798 Supported "Secreted to blood" NA NA 5940000 65000000000 "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB025798: " "unprognostic (7.77e-2)" "unprognostic (4.46e-1)" "unprognostic (2.15e-2)" "unprognostic (2.07e-2)" "unprognostic (2.67e-1)" "unprognostic (3.61e-2)" "unprognostic (5.75e-2)" "unprognostic (2.50e-1)" "unprognostic (2.20e-2)" "unprognostic (4.46e-2)" "unprognostic (4.32e-3)" "unprognostic (6.70e-2)" "unprognostic (9.28e-2)" "unprognostic (4.42e-3)" "unprognostic (2.17e-1)" "unprognostic (3.89e-1)" "unprognostic (1.38e-1)" 11.7 14.6 252.9 2.6 259.8 0.4 4.4 267.5 243.6 9.7 138.2 5.6 2.5 3.2 1.9 2.6 6.0 92.7 154.7 236.0 242.1 52.5 1603.7 5.1 1.0 352.4 314.4 3.5 7.9 6.0 25.8 0.7 304.9 16.3 3.6 26.4 4.9 2.2 43.6 2.0 9.7 5.8 340.5 1.3 4.9 4.1 273.5 1.7 13.2 25.8 0.1 7.0 4.5 322.4 0.2 0.4 0.2 0.2 15.6 0.0 0.9 0.6 0.2 0.0 0.0 80.6 0.1 0.3 0.7 0.2 0.7 0.7 0.0 0.0 0.0 11.4 0.2 0.2 0.3 646.2 1.9 1.0 0.5 26.3 0.0 0.0 0.1 0.1 0.0 0.1 0.1 5.5 0.7 0.0 0.2 0.6 0.6 0.1 0.2 0.3 2.4 0.1 0.1 0.3 0.9 0.6 0.4 0.1 5.5 0.1 0.0 243.6 0.1 0.4 1.3 0.4 1.2 3.5 47.0 0.4 0.4 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 252.9 259.8 267.5 243.6 236.0 242.1 352.4 314.4 304.9 340.5 273.5 322.4 0.8 0.0 1.7 140.0 11.3 0.6 1.1 0.0 0.0 4.7 0.8 0.3 60.0 985.1 0.6 3.7 35.5 0.1 0.0 0.0 25.4 169.8 62.2 0.3 0.4 5.5 0.0 50.8 0.3 10.0 0.2 27.2 0.5 0.1 0.0 0.0 39.3 2244.9 2.1 3.3 1.5 1.1 0.0 56.9 0.4 48.5 4.1 0.9 8.8 5.6 0.6 75.1 0.0 3.5 6.8 13.7 1.2 3.4 0.0 26.2 24.2 146.9 0.1 49.8 13.1 7.2 94.1 0.4 0.4 0.0 0.0 0.7 3.9 0.0 0.4 1.9 AIFM1 "AIF, AUNX1, CMTX4, DFNX5, NAMSD, PDCD8" ENSG00000156709 "Apoptosis inducing factor mitochondria associated 1" O95831 X 130124666-130165879 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "DNA-binding, Oxidoreductase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Dwarfism, Mental retardation, Neurodegeneration, Neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 165.4;Proximal tubular cells: 326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003764, HPA030611" Enhanced Supported Mitochondria NA NA 230000 "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB003764: AB_289587, HPA030611: AB_2673549" "unprognostic (3.00e-3)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.22e-1)" "unprognostic (2.10e-2)" "unprognostic (3.15e-3)" "unprognostic (1.46e-1)" "unprognostic (1.14e-2)" "unprognostic (1.43e-1)" "unprognostic (3.11e-2)" "unprognostic (2.54e-3)" "unprognostic (2.81e-3)" "prognostic favorable (4.42e-10)" "unprognostic (1.76e-2)" "unprognostic (1.14e-1)" "unprognostic (5.04e-2)" "unprognostic (2.11e-2)" 21.0 65.2 10.5 17.6 11.2 11.8 17.8 11.9 12.8 15.7 24.7 34.3 52.9 15.3 8.9 20.8 22.1 10.1 107.7 10.9 11.6 97.3 110.6 13.9 16.2 11.3 11.0 11.9 27.8 29.7 16.2 10.3 11.4 14.8 15.9 8.5 18.6 7.6 68.9 15.2 29.9 10.1 11.2 20.3 41.2 30.3 12.1 18.5 14.7 25.2 11.0 18.4 13.4 11.6 52.8 95.4 22.6 85.2 24.1 14.6 50.0 28.6 19.0 33.5 25.2 55.8 36.4 105.0 113.3 17.5 39.3 47.2 61.3 33.3 12.7 48.2 73.4 61.6 59.1 68.9 34.0 51.5 63.5 26.1 21.7 34.5 22.0 12.1 27.2 83.4 62.6 50.7 13.1 96.7 57.6 74.5 24.4 53.6 65.1 55.6 31.7 132.7 60.8 36.6 46.0 28.2 35.5 68.0 67.5 13.2 46.0 40.8 31.7 20.5 20.4 63.9 58.7 24.2 45.0 47.5 25.3 86.4 33.4 4.1 21.0 14.1 11.8 26.6 13.1 14.6 12.8 14.6 31.7 10.3 12.7 12.6 2.4 20.7 24.8 14.7 17.9 12.4 10.5 11.2 11.9 12.8 10.9 11.6 11.3 11.0 11.4 11.2 12.1 11.6 12.6 16.0 20.1 17.0 17.1 8.7 8.2 25.0 9.1 19.3 13.0 8.3 165.4 22.8 21.2 40.5 22.9 58.0 14.2 31.6 92.0 24.9 1.8 36.7 17.3 11.5 9.6 26.3 10.8 20.5 29.0 16.4 27.0 50.4 10.8 33.1 14.3 92.3 38.0 15.2 12.1 24.0 34.6 14.4 7.4 4.9 17.4 16.8 10.6 8.4 16.6 17.2 20.6 8.0 19.6 18.0 18.9 17.3 19.2 7.9 45.6 326.1 21.3 48.1 6.6 11.3 39.3 10.2 32.0 17.1 6.8 39.7 15.8 45.9 37.2 9.8 AIG1 "AIG-1, dJ95L4.1, FLJ10485" ENSG00000146416 "Androgen induced 1" Q9NVV5 6 143060496-143341058 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 235.8" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 245.4;Proximal tubular cells: 261.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060766 Approved Approved "Golgi apparatus" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "HPA060766: AB_2684356" "unprognostic (2.70e-2)" "prognostic unfavorable (3.26e-6)" "unprognostic (4.27e-2)" "prognostic unfavorable (3.06e-4)" "unprognostic (5.34e-2)" "prognostic unfavorable (3.25e-7)" "unprognostic (1.91e-2)" "unprognostic (8.75e-3)" "unprognostic (2.17e-1)" "unprognostic (5.53e-2)" "unprognostic (2.75e-1)" "unprognostic (1.93e-1)" "unprognostic (2.74e-2)" "unprognostic (3.07e-2)" "unprognostic (1.43e-1)" "unprognostic (9.11e-2)" "unprognostic (2.75e-1)" 42.0 29.8 43.7 10.4 44.6 31.6 30.0 43.3 46.1 17.6 48.2 23.0 46.6 14.4 33.0 34.1 34.4 24.5 54.1 44.1 49.1 102.0 235.8 19.9 10.7 45.0 43.4 34.7 31.0 31.0 36.6 11.9 46.4 22.7 18.8 33.9 19.8 24.1 23.7 16.8 45.9 15.2 47.1 20.1 20.8 15.7 51.0 6.8 42.9 32.5 14.8 29.4 26.1 52.5 32.6 25.2 20.6 56.9 29.7 22.3 7.6 28.3 57.1 26.8 61.9 37.5 81.5 20.0 40.5 66.1 41.7 42.0 26.5 79.2 64.2 67.2 63.0 5.6 35.6 157.3 40.8 46.0 2.7 32.9 76.7 35.7 129.6 88.2 10.9 30.8 4.0 67.6 59.3 45.6 14.2 9.8 40.8 37.4 27.6 20.2 61.6 36.6 100.6 77.6 75.5 42.4 35.5 33.2 17.2 36.0 31.7 96.0 3.0 25.2 27.8 22.7 33.4 99.6 95.1 2.1 59.7 9.5 26.9 12.0 6.2 9.6 6.6 29.3 15.1 9.6 12.4 10.6 33.0 5.6 13.1 10.0 11.3 11.8 35.4 2.9 9.7 9.2 43.7 44.6 43.3 46.1 44.1 49.1 45.0 43.4 46.4 47.1 51.0 52.5 40.8 16.0 27.7 114.9 22.0 25.0 51.8 82.5 27.9 68.3 69.9 65.4 73.7 72.9 66.9 51.5 25.0 79.6 8.6 12.6 52.8 60.3 22.4 99.8 25.9 32.8 39.5 29.3 204.3 31.5 10.5 42.2 26.0 83.1 36.8 90.9 36.8 229.6 32.7 53.8 245.4 33.3 59.0 40.1 42.3 7.0 32.0 37.2 55.2 100.2 18.2 74.3 8.2 105.1 172.9 25.8 65.2 38.4 47.7 35.3 232.9 261.5 69.1 36.9 32.9 41.7 50.8 5.6 17.3 53.1 45.7 108.1 18.5 61.5 42.4 53.2 AK3 "AK3L1, AK6, AKL3L1" ENSG00000147853 "Adenylate kinase 3" Q9UIJ7 9 4709556-4742043 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 242.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 305.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 485.4;HEL: 273.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063324 Enhanced Supported Mitochondria NA NA 31000 "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA063324: AB_2684985" "unprognostic (1.30e-2)" "unprognostic (2.25e-1)" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" "unprognostic (6.55e-2)" "unprognostic (1.02e-1)" "unprognostic (2.21e-3)" "unprognostic (6.44e-2)" "unprognostic (2.81e-2)" "unprognostic (9.81e-3)" "unprognostic (1.90e-1)" "unprognostic (2.76e-2)" "prognostic favorable (6.07e-9)" "unprognostic (1.24e-1)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (1.55e-3)" 75.5 62.9 30.1 23.7 36.9 20.1 39.7 33.5 34.9 41.0 56.2 67.4 68.3 41.9 31.2 61.2 34.4 35.9 100.6 27.0 40.6 101.4 199.9 34.9 29.6 32.8 38.1 47.8 38.9 66.8 22.2 35.1 33.7 49.2 59.6 16.8 38.7 42.6 242.8 47.4 62.5 41.7 33.5 33.0 69.5 11.2 37.9 35.1 49.9 159.6 34.4 48.7 39.7 36.5 44.1 30.7 55.5 22.6 75.3 55.5 4.9 60.4 116.1 30.4 45.5 5.7 43.6 39.5 20.4 63.5 16.6 29.3 40.8 48.0 51.2 485.4 37.1 273.3 56.1 91.3 58.5 28.7 14.1 87.9 41.4 26.4 36.0 70.4 91.2 38.2 22.1 49.6 91.8 22.5 27.5 65.6 53.3 77.1 15.4 38.2 21.1 19.2 82.1 55.7 98.3 63.6 65.7 18.5 35.1 53.7 26.5 53.2 65.9 25.7 28.8 70.1 43.6 15.5 10.5 50.3 46.9 19.9 18.9 13.3 10.2 32.2 27.6 8.1 25.5 12.1 21.6 25.7 19.6 12.3 28.4 29.2 2.8 27.4 6.5 26.3 31.8 21.1 30.1 36.9 33.5 34.9 27.0 40.6 32.8 38.1 33.7 33.5 37.9 36.5 58.3 57.7 80.3 78.0 34.0 74.2 76.4 87.4 84.2 10.7 58.8 28.3 182.9 68.6 71.0 66.2 22.9 95.5 34.6 129.9 258.2 84.8 3.7 40.7 30.6 65.7 109.6 68.1 23.4 69.6 17.0 83.4 87.1 37.8 46.2 75.8 79.2 305.6 47.5 15.2 55.8 104.2 73.2 46.9 41.4 4.5 108.7 34.7 74.7 22.5 40.9 28.2 33.0 44.7 87.0 67.3 78.7 149.7 62.8 166.7 111.8 183.5 52.8 11.0 105.2 76.0 60.8 6.4 14.1 152.5 104.4 214.0 36.4 68.5 145.5 151.6 AKAP1 "AKAP121, AKAP149, AKAP84, D-AKAP1, PPP1R43, PRKA1, S-AKAP84, SAKAP84, TDRD17" ENSG00000121057 "A-kinase anchoring protein 1" Q92667 17 57085092-57121346 "Predicted intracellular proteins, Predicted membrane proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 207.8" "Group enriched" "Detected in all" 9 "Early spermatids: 584.7;Late spermatids: 2219.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008620, HPA008691, CAB019286" Supported Supported Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "CAB019286: , HPA008620: AB_2668104, HPA008691: AB_1078119" "unprognostic (5.52e-2)" "unprognostic (1.83e-1)" "unprognostic (6.96e-3)" "unprognostic (1.78e-1)" "unprognostic (1.79e-2)" "unprognostic (6.38e-2)" "unprognostic (7.19e-2)" "unprognostic (1.48e-2)" "unprognostic (8.14e-2)" "unprognostic (2.36e-2)" "unprognostic (3.22e-1)" "unprognostic (3.00e-1)" "prognostic favorable (7.86e-9)" "unprognostic (6.82e-2)" "unprognostic (2.46e-1)" "unprognostic (5.74e-2)" "unprognostic (1.38e-1)" 40.6 15.5 31.6 17.8 35.2 6.9 35.2 29.1 35.2 23.7 17.2 76.1 54.8 24.5 19.7 36.4 31.5 18.0 82.6 28.5 26.5 26.2 49.9 19.6 10.8 26.7 27.1 20.0 22.2 48.1 17.1 7.1 26.9 34.7 48.9 34.7 33.6 24.8 207.8 27.3 55.8 26.3 21.9 11.3 55.4 112.9 29.8 11.4 36.3 137.9 9.5 46.8 25.5 28.0 46.1 54.3 80.7 27.5 18.2 12.8 46.8 19.0 18.3 24.2 16.8 61.2 42.2 74.1 52.3 14.5 26.5 74.6 50.1 44.4 24.7 40.6 63.5 63.1 51.4 118.1 19.4 59.9 23.8 11.7 41.8 26.2 39.2 14.4 25.7 22.9 42.3 28.6 14.8 39.8 76.1 24.1 28.7 97.9 61.7 58.2 32.8 61.0 17.1 61.9 58.9 40.3 15.8 45.1 23.9 16.6 31.4 61.4 18.8 24.3 24.2 28.3 45.0 28.9 36.9 55.8 14.0 47.5 19.7 1.6 1.0 0.4 2.6 2.0 2.3 1.8 2.0 2.1 2.3 1.2 4.0 2.1 0.1 3.3 0.5 4.0 1.7 1.3 31.6 35.2 29.1 35.2 28.5 26.5 26.7 27.1 26.9 21.9 29.8 28.0 34.5 35.3 49.9 26.4 16.6 22.6 23.5 11.9 32.5 33.0 29.4 42.3 154.9 28.6 32.1 5.5 47.9 21.5 10.6 89.1 1.9 16.3 584.7 16.8 12.6 16.4 45.9 12.6 14.9 16.3 13.8 12.2 54.0 37.8 3.8 21.0 11.4 60.2 9.5 37.0 26.3 86.6 8.2 9.0 9.5 2219.5 19.6 10.9 7.2 4.7 8.7 8.2 3.1 10.6 9.6 12.7 68.5 13.9 13.2 32.3 65.6 7.4 6.5 77.1 46.0 17.9 54.4 18.3 14.9 44.9 19.7 6.8 11.5 13.3 117.6 17.0 AKAP9 "AKAP350, AKAP450, CG-NAP, HYPERION, KIAA0803, LQT11, MU-RMS-40.16A, PPP1R45, PRKA9, YOTIAO" ENSG00000127914 "A-kinase anchoring protein 9" Q99996 7 91940840-92110673 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 2230.9;Rod photoreceptor cells: 1279.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008548, CAB012909, HPA026109" Supported Enhanced "Golgi apparatus,Vesicles,Centrosome" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 54: Non-specific - Microtubule organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus" "Vesicles, Centrosome" "CAB012909: AB_2533235, HPA008548: AB_1078121, HPA026109: AB_1844688" "unprognostic (9.57e-2)" "unprognostic (1.66e-1)" "unprognostic (2.13e-1)" "unprognostic (5.97e-3)" "unprognostic (1.20e-1)" "unprognostic (1.47e-1)" "unprognostic (4.75e-2)" "unprognostic (1.31e-2)" "unprognostic (1.28e-1)" "unprognostic (6.59e-2)" "unprognostic (7.59e-2)" "unprognostic (6.32e-2)" "prognostic favorable (2.10e-6)" "unprognostic (8.89e-2)" "unprognostic (1.73e-1)" "unprognostic (7.77e-2)" "unprognostic (3.96e-2)" 7.1 8.3 8.6 6.2 9.0 8.6 11.0 15.3 14.1 6.5 15.5 16.0 16.5 6.4 3.9 7.9 8.4 10.4 6.5 8.6 11.0 13.2 16.2 7.8 5.8 8.8 9.6 11.9 9.5 12.7 8.6 5.4 9.0 7.5 14.6 31.4 9.6 3.8 16.2 6.8 18.6 4.0 7.7 5.0 9.4 4.1 11.9 9.3 9.3 10.0 5.3 5.5 7.2 9.7 11.7 8.1 9.6 5.8 11.6 11.3 6.2 8.7 6.3 4.9 5.9 10.3 8.0 9.2 12.5 7.3 7.5 8.3 10.5 5.6 9.2 9.8 8.2 10.9 11.6 7.3 4.0 18.5 9.6 6.2 6.2 9.1 8.8 7.7 10.3 10.6 19.3 13.0 7.4 14.1 10.4 7.0 8.3 6.5 8.4 7.6 18.2 6.2 4.9 11.5 13.3 11.0 19.0 16.9 10.1 11.1 5.1 9.8 17.5 9.5 11.2 14.5 12.6 7.3 13.0 13.6 6.2 7.8 9.4 1.1 0.6 0.9 1.3 0.6 0.9 1.9 1.1 1.1 0.4 1.6 1.2 1.0 0.7 1.2 0.6 3.2 1.0 0.2 8.6 9.0 15.3 14.1 8.6 11.0 8.8 9.6 9.0 7.7 11.9 9.7 123.3 525.6 357.0 141.3 143.3 103.5 126.5 112.6 170.8 273.5 165.4 150.9 253.2 297.4 208.4 176.6 2230.9 141.4 201.5 293.4 101.8 131.0 22.5 392.3 157.7 115.9 185.1 129.4 142.6 92.6 81.9 123.5 152.9 185.0 136.6 386.1 98.2 153.5 57.2 360.1 182.6 350.8 136.3 78.3 88.4 17.5 173.4 101.6 58.7 115.2 121.5 155.7 119.4 169.9 187.1 102.4 218.9 135.8 193.5 91.4 298.5 47.2 506.3 1279.6 138.1 206.1 116.1 83.0 129.0 87.3 111.8 333.8 145.7 135.8 171.4 97.6 AKR1C8P AKR1CL1 ENSG00000264006 "Aldo-keto reductase family 1 member C8, pseudogene" Q5T2L2 10 5154140-5185187 "Predicted intracellular proteins" Oxidoreductase "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 10 "choroid plexus: 3.3;epididymis: 3.4;liver: 8.1" "Cell type enhanced" "Detected in single" "Microglial cells: 1.0" "Cancer enriched" "Detected in single" 9 "liver cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 41 "HDLM-2: 19.5" NA NA "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (3.47e-1)" "unprognostic (2.14e-1)" "unprognostic (4.76e-1)" "unprognostic (4.20e-2)" "unprognostic (3.69e-1)" "unprognostic (3.07e-1)" "unprognostic (1.10e-1)" "unprognostic (1.92e-2)" "unprognostic (2.66e-2)" "unprognostic (6.28e-3)" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 8.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 19.5 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALCAM "CD166, MEMD" ENSG00000170017 "Activated leukocyte cell adhesion molecule" Q13740 3 105366909-105576900 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Cell adhesion, Immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 438.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 737.2;Oligodendrocyte precursor cells: 680.1;Oligodendrocytes: 981.1;Respiratory ciliated cells: 318.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 29.6" "Lineage enriched" "Detected in many" 6 "dendritic cells: 29.6" "Cell line enhanced" "Detected in many" "hTERT-HME1: 393.4;U-138 MG: 473.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002148, HPA010926" Enhanced Uncertain Vesicles "Secreted to blood" NA NA 1600000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "CAB002148: AB_442053, HPA010926: AB_1078449" "unprognostic (6.82e-2)" "unprognostic (2.66e-1)" "unprognostic (2.13e-1)" "unprognostic (2.19e-1)" "unprognostic (9.48e-3)" "unprognostic (2.08e-2)" "unprognostic (1.63e-3)" "unprognostic (3.89e-2)" "unprognostic (1.75e-1)" "unprognostic (4.01e-2)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.15e-4)" "unprognostic (3.15e-1)" "unprognostic (4.47e-2)" "unprognostic (9.57e-2)" "unprognostic (7.76e-2)" 7.7 32.7 31.3 12.2 48.1 10.5 81.0 42.4 47.2 28.0 14.4 16.6 17.0 15.5 35.4 8.2 49.1 23.3 9.6 32.4 70.6 22.2 47.9 74.1 9.9 50.7 54.9 57.6 32.7 438.9 19.2 12.1 51.7 32.7 14.5 3.6 33.8 39.6 0.8 11.0 17.4 16.2 44.9 6.3 33.4 4.5 45.7 14.2 62.4 5.0 14.5 25.6 6.4 85.0 248.4 93.7 65.9 33.7 97.6 42.7 0.6 197.7 115.1 124.9 173.8 0.8 50.5 17.3 80.3 280.6 68.8 186.5 10.6 157.4 366.1 16.6 16.6 2.4 65.8 4.6 109.6 101.3 0.8 76.0 114.9 159.9 393.4 346.8 139.3 17.9 0.3 28.6 165.9 16.9 14.5 37.0 13.7 79.3 104.8 9.4 5.9 1.0 188.9 27.2 47.5 131.9 20.6 19.6 12.9 25.9 37.7 66.3 291.6 473.7 162.3 20.9 237.2 0.3 0.6 1.8 108.0 21.1 207.4 0.0 4.7 3.5 0.6 2.1 1.9 4.7 1.5 0.9 29.6 3.0 0.3 0.2 5.3 0.6 1.2 10.5 2.4 3.2 31.3 48.1 42.4 47.2 32.4 70.6 50.7 54.9 51.7 44.9 45.7 85.0 4.5 737.2 143.6 238.6 17.9 12.1 22.8 65.8 12.0 3.0 112.4 47.9 10.1 62.9 255.3 16.5 2.1 0.7 19.5 9.1 1.9 18.5 66.5 108.6 20.1 11.9 16.8 6.3 143.0 43.0 0.7 37.0 23.4 158.1 11.4 29.5 3.6 44.1 57.5 1.7 287.0 16.3 46.8 51.0 162.6 60.1 3.7 86.4 24.9 40.3 93.4 1.3 1.0 680.1 981.1 55.2 8.5 6.4 21.8 117.5 9.6 24.2 318.3 0.8 0.0 7.9 21.8 8.1 5.5 30.1 20.2 0.8 8.9 22.8 10.4 105.4 ALDH8A1 ALDH12 ENSG00000118514 "Aldehyde dehydrogenase 8 family member A1" Q9H2A2 6 134917393-134950115 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 16 "kidney: 72.2;liver: 247.2" "Group enriched" "Detected in some" 4 "Hepatocytes: 142.5;Proximal tubular cells: 136.9" "Group enriched" "Detected in some" 7 "liver cancer: 26.3;renal cancer: 17.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HEK 293: 2.9;Hep G2: 2.9;K-562: 3.0;RPTEC TERT1: 3.3;U-266/70: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA026292, HPA055414" Enhanced Approved Nucleoplasm,Centrosome NA NA 110000 "Cluster 46: Basophils - DNA binding" "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Centrosome Nucleoplasm "HPA026292: AB_1844741, HPA055414: AB_2682810" "unprognostic (1.12e-1)" "unprognostic (1.48e-1)" "unprognostic (1.88e-1)" "unprognostic (1.75e-1)" "unprognostic (2.70e-2)" "unprognostic (6.32e-2)" "unprognostic (4.30e-3)" "unprognostic (1.12e-1)" "unprognostic (3.98e-2)" "unprognostic (1.64e-1)" "unprognostic (2.39e-2)" "unprognostic (3.99e-2)" "prognostic favorable (9.87e-4)" "unprognostic (1.25e-2)" "unprognostic (1.36e-1)" "unprognostic (2.36e-2)" "unprognostic (5.86e-5)" 1.3 1.3 6.4 0.7 7.1 2.4 1.2 6.9 9.8 1.5 2.2 3.3 0.8 1.2 2.1 0.8 1.0 0.9 0.7 6.5 3.8 72.2 247.2 0.9 0.6 5.3 4.4 0.5 0.9 0.4 0.8 0.5 6.2 1.7 0.8 2.8 0.8 0.8 3.6 1.7 1.1 0.9 3.1 1.3 1.2 0.5 5.4 0.7 0.6 0.3 0.6 1.9 0.9 8.3 0.1 0.5 0.8 0.5 0.2 0.1 0.6 0.2 0.2 0.0 0.5 0.2 0.3 0.1 0.2 0.0 0.1 0.6 0.6 0.0 0.4 0.6 2.9 2.0 2.1 2.9 0.3 0.8 1.0 0.8 0.9 0.2 0.4 0.6 0.2 0.8 3.0 1.1 0.1 0.0 0.9 1.0 0.2 0.2 0.3 0.0 0.2 0.2 3.3 0.4 0.8 0.2 0.1 0.0 0.5 0.2 0.3 0.2 0.2 0.2 1.6 0.6 0.8 2.8 1.0 0.5 0.3 0.7 0.2 2.5 0.3 0.3 0.4 0.1 0.1 0.4 0.4 0.2 0.0 0.4 0.3 0.3 0.8 0.8 0.1 0.4 0.5 0.3 6.4 7.1 6.9 9.8 6.5 3.8 5.3 4.4 6.2 3.1 5.4 8.3 0.3 3.2 0.6 3.6 0.8 0.0 0.2 0.2 0.0 2.6 0.7 0.9 0.6 1.5 0.7 31.3 0.0 0.2 0.3 0.1 19.6 0.2 0.1 0.4 0.4 0.7 0.0 0.0 14.3 0.0 1.7 0.4 0.0 1.6 0.0 0.5 2.5 142.5 0.1 3.3 12.9 0.1 0.0 2.5 0.3 0.0 0.0 0.8 0.0 1.0 0.7 0.3 0.0 3.0 9.6 0.0 0.1 0.0 0.3 0.1 0.0 136.9 0.0 1.8 0.0 1.2 0.5 0.0 0.0 0.0 0.4 0.0 0.9 0.5 0.2 0.1 ALDH9A1 "ALDH4, ALDH7, ALDH9, E3" ENSG00000143149 "Aldehyde dehydrogenase 9 family member A1" P49189 1 165662216-165698863 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 311.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA006077, HPA010873" Approved Approved Cytosol "Intracellular and membrane" NA NA 2000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA006077: , HPA010873: AB_1078126" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (4.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.21e-2)" "unprognostic (1.25e-1)" "unprognostic (4.14e-2)" "unprognostic (4.87e-2)" "unprognostic (2.30e-1)" "unprognostic (1.83e-1)" "prognostic favorable (4.56e-4)" "unprognostic (5.51e-2)" "unprognostic (9.05e-2)" "unprognostic (1.67e-1)" "unprognostic (1.49e-1)" "unprognostic (1.43e-1)" "unprognostic (2.15e-1)" 119.2 105.5 49.6 29.8 51.0 24.8 76.8 49.3 60.3 51.5 62.5 45.7 54.8 38.6 93.4 105.6 50.2 32.0 48.2 47.4 57.5 142.4 206.5 38.5 40.3 50.5 52.1 53.6 44.0 81.9 39.9 38.0 51.4 65.3 50.6 46.4 104.1 45.6 93.6 54.7 48.6 42.0 50.7 37.9 39.5 63.4 49.3 39.0 123.0 56.4 60.1 39.4 43.9 55.6 55.7 53.5 48.7 44.1 152.1 132.8 40.7 71.9 101.5 70.8 61.0 33.4 40.7 0.1 67.1 64.8 34.9 42.8 40.0 70.3 83.0 25.9 50.6 35.3 34.7 36.5 78.2 56.0 36.1 86.0 34.8 75.2 62.5 97.8 62.2 45.9 56.9 48.4 111.7 33.4 37.6 57.6 71.3 145.1 64.7 31.7 62.0 74.3 92.5 52.0 57.7 39.8 51.4 57.1 67.4 65.6 108.8 84.0 61.9 42.5 41.5 52.4 37.1 44.7 62.5 54.8 47.9 52.6 41.7 61.8 35.2 50.9 45.5 37.7 48.8 49.9 43.8 49.6 34.5 46.8 43.8 50.4 51.3 43.0 45.3 21.6 69.8 45.6 49.6 51.0 49.3 60.3 47.4 57.5 50.5 52.1 51.4 50.7 49.3 55.6 56.2 16.0 47.6 12.7 43.3 32.6 43.3 43.8 68.3 25.0 83.0 54.6 46.5 55.8 36.8 51.5 22.9 48.5 39.3 43.9 97.8 42.9 45.4 27.7 39.1 49.4 55.8 28.2 5.6 37.0 76.4 60.6 36.2 20.4 38.0 60.9 59.3 158.8 61.9 13.5 8.3 56.9 32.6 59.1 24.9 39.8 95.4 43.8 56.9 6.5 34.6 311.5 39.1 12.1 12.2 32.2 33.1 115.5 34.8 39.6 80.3 204.4 59.4 28.9 26.3 32.5 40.1 85.6 49.9 123.8 51.9 38.2 43.7 148.4 63.6 28.3 ALG8 MGC2840 ENSG00000159063 "ALG8 alpha-1,3-glucosyltransferase" Q9BVK2 11 78095244-78139660 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 105.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051898 Approved Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "HPA051898: AB_2681656" "unprognostic (1.37e-1)" "unprognostic (9.24e-2)" "unprognostic (4.60e-2)" "unprognostic (2.69e-2)" "unprognostic (2.65e-1)" "unprognostic (6.49e-2)" "unprognostic (5.38e-3)" "unprognostic (5.91e-2)" "unprognostic (1.39e-1)" "unprognostic (1.10e-3)" "unprognostic (5.29e-2)" "unprognostic (1.20e-1)" "unprognostic (1.35e-2)" "unprognostic (1.19e-1)" "unprognostic (2.34e-1)" "unprognostic (3.78e-2)" "unprognostic (6.37e-2)" 22.8 33.0 12.7 13.4 14.3 9.2 25.6 13.9 16.4 18.7 15.4 17.5 13.3 15.9 33.2 19.0 18.8 12.0 17.9 12.9 13.3 24.9 47.1 15.0 14.6 14.1 13.1 22.1 23.8 23.7 19.8 18.7 13.8 19.1 21.8 10.4 21.7 18.0 12.1 16.6 15.5 16.4 13.5 18.3 20.2 43.5 13.1 17.8 22.4 8.9 19.8 18.4 16.0 15.2 27.8 74.4 62.8 56.6 63.7 42.5 37.6 38.6 57.8 68.6 67.4 127.9 102.0 61.4 74.5 51.5 92.3 86.5 87.0 56.5 111.9 46.3 50.8 74.3 56.5 62.2 38.9 71.8 39.6 34.4 36.4 81.8 37.9 37.5 50.3 58.0 98.2 65.8 97.7 38.6 53.3 61.9 81.9 200.5 38.1 63.6 32.6 168.3 70.0 40.4 20.2 44.8 62.0 102.2 29.4 65.6 106.5 50.8 32.0 43.5 50.6 102.5 35.1 46.6 88.0 80.3 26.7 71.4 84.4 1.2 30.0 5.4 25.1 34.5 29.1 37.2 25.5 25.7 34.2 31.3 29.7 26.2 2.6 29.1 39.9 33.1 22.5 27.6 12.7 14.3 13.9 16.4 12.9 13.3 14.1 13.1 13.8 13.5 13.1 15.2 11.9 12.8 11.6 12.4 21.0 10.5 23.3 49.6 26.2 14.7 18.3 16.3 6.9 20.0 35.2 20.2 18.8 53.8 9.1 7.0 5.9 24.4 18.9 11.0 16.9 17.2 7.8 9.9 21.3 25.4 59.5 19.4 11.7 13.8 11.4 36.4 9.3 40.2 31.4 16.8 18.0 15.9 32.6 17.0 10.8 14.0 18.0 15.3 26.6 12.2 12.3 8.2 21.6 13.0 20.7 17.7 6.4 15.8 43.1 16.9 7.7 15.8 21.7 13.5 0.0 14.2 19.6 105.0 37.8 20.9 8.9 32.7 15.2 16.9 16.8 15.2 ALKAL1 "AUGB, FAM150A, UNQ9433" ENSG00000196711 "ALK and LTK ligand 1" Q6UXT8 8 52534037-52565430 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 2.4;thyroid gland: 2.4" "Cell type enriched" "Detected in some" 4 "Distal tubular cells: 5.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "CAPAN-2: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027368 Uncertain "Secreted - unknown location" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 30: Mammary glandular cells - Lactation" "HPA027368: AB_10602317" "unprognostic (1.18e-1)" "unprognostic (1.13e-4)" "unprognostic (9.47e-2)" "unprognostic (9.64e-2)" "unprognostic (1.52e-1)" "unprognostic (6.60e-2)" "unprognostic (1.70e-4)" "unprognostic (4.48e-2)" "unprognostic (1.71e-1)" "unprognostic (1.34e-1)" "unprognostic (9.58e-3)" 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 1.2 0.0 1.1 0.6 0.0 0.0 0.0 0.2 2.4 0.0 0.0 0.2 0.1 0.2 0.3 0.0 0.5 0.1 0.0 0.3 0.0 0.0 0.0 0.5 0.5 0.1 0.0 0.8 0.0 0.0 0.0 0.5 0.7 0.2 0.0 0.4 0.1 0.1 0.0 2.4 0.0 0.0 1.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.5 0.1 0.5 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 5.9 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALKAL2 "AUGA, FAM150B" ENSG00000189292 "ALK and LTK ligand 2" Q6UX46 2 279558-288851 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 205.4" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 20.3;Ductal cells: 37.0;Endometrial ciliated cells: 24.0;Glandular and luminal cells: 50.3;Granulosa cells: 64.3;Proximal tubular cells: 28.1" "Cancer enhanced" "Detected in many" "renal cancer: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 20 "AF22: 138.8" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "amygdala: 4.3;basal ganglia: 3.0;cerebral cortex: 2.5;hippocampal formation: 3.4;spinal cord: 2.3" "Secreted - unknown location" NA NA "Cluster 51: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.39e-3)" "unprognostic (1.44e-2)" "unprognostic (2.41e-2)" "unprognostic (2.03e-3)" "unprognostic (2.88e-1)" "unprognostic (3.73e-2)" "unprognostic (1.34e-2)" "unprognostic (2.72e-2)" "unprognostic (1.40e-1)" "unprognostic (1.11e-1)" "unprognostic (2.07e-1)" "unprognostic (7.06e-2)" "unprognostic (1.47e-1)" "unprognostic (3.35e-1)" "unprognostic (9.29e-3)" "unprognostic (5.19e-2)" "unprognostic (3.68e-1)" 28.8 205.4 4.6 2.0 6.3 0.6 26.6 3.5 2.9 4.9 4.8 8.2 3.7 26.4 13.4 2.0 26.2 10.7 2.2 3.1 5.4 21.1 4.5 34.0 0.9 3.6 2.1 74.4 64.3 2.3 8.6 9.6 2.7 6.5 6.5 0.4 5.4 2.6 1.5 17.3 7.7 9.9 1.8 12.3 17.3 35.5 5.1 1.7 10.4 0.5 1.6 4.7 5.3 4.8 0.0 0.0 138.8 0.1 0.8 0.0 0.3 0.2 0.0 0.0 0.0 0.6 0.0 0.4 1.3 0.0 0.0 0.2 0.5 0.0 0.0 0.5 0.3 0.0 0.1 0.7 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.1 0.0 0.2 2.4 0.0 0.0 6.8 0.4 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 2.8 0.0 0.5 0.0 0.1 0.1 0.2 0.2 0.3 0.7 0.1 0.3 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.2 0.1 4.6 6.3 3.5 2.9 3.1 5.4 3.6 2.1 2.7 1.8 5.1 4.8 2.5 0.0 11.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 14.6 20.3 0.0 0.0 0.0 1.8 0.0 0.1 1.4 0.0 3.9 37.0 0.0 24.0 6.3 4.5 0.0 0.0 0.0 0.7 0.1 3.1 0.0 50.3 0.0 64.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 28.1 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.1 0.6 0.9 0.0 0.0 ALOX5 5-LOX ENSG00000012779 "Arachidonate 5-lipoxygenase" P09917 10 45374176-45446119 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Leukotriene biosynthesis" "Dioxygenase, Hydrolase, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 72.8;lymphoid tissue: 93.9" "Cell type enhanced" "Detected in many" "B-cells: 63.7;granulocytes: 201.3;Hofbauer cells: 85.0;Kupffer cells: 78.5;Macrophages: 86.5;monocytes: 59.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 13.9;Daudi: 40.9;HMC-1: 24.0;U-266/70: 30.8;U-698: 11.0" "Region enriched" "Detected in single" 4 "white matter: 2.9" "Low region specificity" "Detected in all" HPA071285 Enhanced Supported Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA071285: AB_2686379" "unprognostic (2.57e-2)" "unprognostic (2.81e-1)" "unprognostic (4.82e-2)" "unprognostic (1.75e-2)" "unprognostic (7.98e-3)" "unprognostic (1.26e-1)" "unprognostic (5.32e-2)" "unprognostic (8.69e-2)" "unprognostic (1.86e-2)" "unprognostic (6.91e-2)" "unprognostic (5.04e-2)" "unprognostic (3.42e-1)" "prognostic unfavorable (1.80e-5)" "unprognostic (5.59e-3)" "unprognostic (4.22e-2)" "unprognostic (1.53e-1)" "prognostic favorable (7.18e-4)" 16.8 8.4 1.4 8.4 1.1 31.1 12.7 2.8 2.9 6.1 1.0 11.0 3.0 6.9 0.3 10.7 11.1 3.4 6.7 1.2 1.8 8.3 5.5 72.8 6.7 4.1 2.5 2.6 23.2 0.9 3.2 3.6 2.7 11.8 2.3 0.1 14.1 1.5 2.1 5.6 35.8 4.9 2.5 93.9 9.3 2.1 2.2 2.6 4.7 3.7 8.9 40.0 7.9 4.2 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 7.4 40.9 0.7 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.1 8.6 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 5.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.1 0.0 2.7 0.0 5.2 0.7 0.0 0.0 0.2 0.0 0.1 0.1 0.6 0.0 0.0 2.2 0.0 0.0 30.8 2.8 11.0 0.0 0.1 0.0 462.5 225.6 317.6 0.3 198.4 0.6 133.9 5.3 1.7 119.7 98.5 0.7 0.5 457.8 0.2 210.5 2.4 1.2 136.1 1.4 1.1 2.8 2.9 1.2 1.8 4.1 2.5 2.7 2.5 2.2 4.2 0.7 16.0 38.4 1.3 63.7 1.1 7.3 0.2 1.2 1.3 7.3 4.3 2.2 12.8 9.5 9.2 2.1 0.7 1.7 1.7 0.0 20.9 0.5 0.7 0.5 3.0 7.1 1.7 2.8 21.6 2.0 1.7 13.7 4.4 201.3 2.2 3.6 1.1 85.0 0.0 1.1 2.0 14.2 78.5 17.8 1.1 0.3 86.5 0.0 47.8 59.5 0.7 4.1 4.0 1.4 18.4 0.6 0.0 13.8 4.0 9.4 0.2 2.6 0.3 13.1 0.3 1.1 0.3 1.1 9.2 1.4 4.1 5.9 0.7 3.2 45.3 AMHR2 "MISR2, MISRII" ENSG00000135409 "Anti-Mullerian hormone receptor type 2" Q16671 12 53423855-53431672 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, Pseudohermaphroditism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 41.5;ovary: 33.1" "Group enriched" "Detected in some" 4 "granulocytes: 26.0;Granulosa cells: 36.1;Theca cells: 94.9" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "HEL: 40.1;K-562: 22.2" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 11 "hippocampal formation: 9.4" "HPA060228, HPA069636" Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 51: Non-specific - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 52: Non-specific - Transcription" Vesicles "Nucleoplasm, Cytosol" "HPA060228: AB_2684227, HPA069636: AB_2686163" "unprognostic (5.79e-2)" "unprognostic (3.65e-1)" "unprognostic (3.98e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (4.61e-3)" "unprognostic (2.33e-1)" "unprognostic (1.44e-2)" "unprognostic (2.91e-1)" "unprognostic (4.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.32e-1)" "unprognostic (2.15e-2)" "unprognostic (3.34e-2)" "unprognostic (1.42e-1)" "unprognostic (2.04e-1)" "unprognostic (1.97e-1)" 0.6 41.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.3 0.4 0.1 0.5 0.0 0.3 0.0 0.9 0.4 0.0 0.0 0.2 33.1 12.5 0.4 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 4.2 0.1 0.1 0.0 0.0 5.7 0.7 9.1 0.5 0.0 0.0 1.8 0.0 0.2 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.6 40.1 0.0 0.8 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 22.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 3.5 2.6 0.0 0.1 1.5 0.0 4.2 0.1 2.1 0.1 2.7 0.0 0.1 26.0 36.1 11.4 0.3 0.1 0.0 0.0 0.0 0.0 1.2 0.0 2.5 5.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.1 0.3 0.0 0.0 0.3 0.8 94.9 0.1 0.0 AMPH ENSG00000078053 Amphiphysin P49418 7 38383704-38631420 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 48.9;pituitary gland: 21.3;retina: 65.9" "Group enriched" "Detected in many" 5 "Bipolar cells: 72.2;Cone photoreceptor cells: 87.6;Excitatory neurons: 228.2;Inhibitory neurons: 198.4;Oligodendrocyte precursor cells: 96.5;Rod photoreceptor cells: 59.4" "Cancer enhanced" "Detected in many" "glioma: 3.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 64.6;ASC TERT1: 37.8;BJ hTERT+ SV40 Large T+: 25.4;BJ hTERT+ SV40 Large T+ RasG12V: 29.9;GAMG: 44.8;HBF TERT88: 23.1;U-138 MG: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008559, HPA019828, HPA019829" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Plasma membrane" "CAB008559: AB_1611845, HPA019828: AB_1844801, HPA019829: AB_1844802" "unprognostic (1.76e-2)" "unprognostic (1.59e-1)" "unprognostic (5.94e-2)" "unprognostic (7.36e-2)" "unprognostic (3.24e-3)" "unprognostic (2.92e-1)" "unprognostic (4.90e-2)" "unprognostic (2.55e-2)" "unprognostic (4.37e-1)" "unprognostic (1.08e-1)" "prognostic favorable (9.96e-4)" "unprognostic (5.06e-2)" "unprognostic (5.81e-5)" "unprognostic (1.23e-2)" "unprognostic (5.63e-2)" "unprognostic (8.03e-2)" "unprognostic (1.68e-3)" 6.5 1.3 19.2 1.5 21.9 0.0 5.9 7.2 48.9 5.8 0.0 3.7 0.5 4.0 3.4 3.2 4.7 3.0 5.4 27.3 28.8 2.6 0.4 1.0 0.4 11.2 0.8 0.9 1.8 0.3 21.3 0.0 10.9 1.4 1.4 65.9 2.5 2.9 3.6 1.3 1.8 3.8 7.9 1.9 2.8 2.5 5.4 0.7 1.7 9.6 0.2 2.4 2.9 17.5 0.0 0.0 16.7 0.0 64.6 37.8 0.0 2.4 0.0 25.4 29.9 0.0 0.0 0.0 0.0 4.8 44.8 0.0 0.0 0.0 23.1 0.0 2.0 0.2 0.0 0.0 0.0 0.3 0.1 22.4 0.0 0.0 0.0 0.1 2.0 0.6 0.0 0.5 0.1 0.3 0.0 0.3 8.5 0.0 0.0 0.0 0.0 1.9 0.0 0.1 4.9 0.0 0.0 0.0 0.7 0.5 0.1 0.0 0.0 24.6 17.1 8.8 9.8 0.1 0.3 0.0 16.8 0.3 22.6 0.0 0.2 0.0 0.6 0.0 0.4 0.0 0.2 0.3 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.4 0.0 0.0 19.2 21.9 7.2 48.9 27.3 28.8 11.2 0.8 10.9 7.9 5.4 17.5 0.8 0.0 0.0 22.5 0.6 0.3 0.1 0.0 0.0 72.2 3.1 2.2 7.9 0.0 0.0 0.0 87.6 0.0 0.3 0.0 1.9 0.3 9.9 0.4 3.2 1.1 0.0 0.0 228.2 0.0 0.0 8.6 0.0 0.3 0.0 0.2 3.9 0.1 0.1 1.7 198.4 0.0 0.0 13.0 1.1 15.0 2.8 0.7 0.0 22.5 0.5 7.6 3.1 96.5 5.5 0.1 0.0 4.9 0.1 0.0 0.0 0.0 0.0 59.4 6.6 8.3 8.4 4.7 2.8 0.0 0.3 0.0 0.6 2.0 0.0 0.0 ANG "RAA1, RNASE5" ENSG00000214274 Angiogenin P03950 14 20684177-20698971 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Differentiation, Stress response" "Developmental protein, DNA-binding, Endonuclease, Hydrolase, Nuclease, Protein synthesis inhibitor" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 52 "liver: 3018.1" "Cell type enriched" "Detected in many" 24 "Hepatocytes: 4816.3" "Cancer enriched" "Detected in all" 17 "liver cancer: 279.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.5;myeloid DC: 14.5" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Hep G2: 152.2;OE19: 116.1" "Low region specificity" "Detected in all" HPA055896 Approved "Nucleoli,Nucleoli rim,Mitotic chromosome,Actin filaments" "Secreted to blood" Yes No 308000000 410000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Nucleoli, Nucleoli rim, Mitotic chromosome" "Actin filaments" "HPA055896: " "unprognostic (2.50e-2)" "unprognostic (1.82e-1)" "unprognostic (9.77e-2)" "prognostic favorable (6.85e-4)" "unprognostic (5.71e-3)" "unprognostic (6.99e-2)" "prognostic favorable (7.83e-5)" "unprognostic (1.16e-1)" "unprognostic (3.20e-3)" "unprognostic (9.19e-3)" "unprognostic (1.31e-1)" "unprognostic (3.69e-1)" "unprognostic (6.65e-2)" "unprognostic (1.03e-1)" "unprognostic (3.39e-1)" "unprognostic (2.00e-1)" "unprognostic (3.09e-1)" 37.6 3.0 3.6 6.0 3.5 1.0 37.8 3.5 4.9 38.2 5.6 32.6 23.2 23.4 17.9 9.8 30.5 28.5 16.9 3.6 4.9 18.4 3018.1 18.5 3.5 4.5 4.2 58.1 30.8 5.3 5.0 3.8 4.3 32.7 45.7 2.2 52.6 13.3 6.2 27.4 27.1 10.4 4.5 7.4 58.2 10.2 3.7 1.5 8.8 10.5 4.1 24.8 31.4 4.8 3.7 9.9 2.3 0.0 23.9 27.8 0.3 4.8 8.8 1.1 4.0 5.9 5.1 0.4 1.5 12.0 8.0 3.8 2.8 3.1 1.3 18.4 3.8 0.9 5.1 152.2 5.0 4.0 0.5 22.2 2.5 1.5 5.1 11.8 5.7 4.2 0.2 27.0 3.5 0.7 0.9 1.2 0.7 116.1 10.7 0.7 3.9 11.3 2.3 2.9 0.0 0.4 4.6 1.7 6.5 5.1 4.0 0.7 6.0 1.9 2.8 1.7 0.7 5.9 4.8 0.5 3.2 2.0 5.0 0.0 24.5 0.0 0.6 2.9 0.4 5.8 1.2 1.1 14.5 4.9 0.3 0.2 0.4 0.0 0.1 2.3 0.8 7.1 3.6 3.5 3.5 4.9 3.6 4.9 4.5 4.2 4.3 4.5 3.7 4.8 9.7 28.9 17.7 0.0 9.7 27.1 43.3 39.2 14.2 0.1 33.8 24.8 0.8 194.5 24.6 11.0 0.0 1.6 0.7 32.5 11.7 40.0 1.0 6.2 9.7 11.0 71.0 27.8 0.0 31.6 5.3 48.8 56.1 24.9 0.0 10.7 62.4 4816.3 15.9 0.0 0.0 171.9 12.2 95.9 18.7 2.9 71.1 13.8 23.2 0.0 4.9 10.1 0.0 0.0 0.0 21.6 33.3 24.0 11.7 43.7 91.3 61.2 76.5 0.6 13.1 29.7 17.7 1.0 1.3 9.4 52.4 9.3 5.6 0.5 51.6 39.2 ANGPT2 Ang2 ENSG00000091879 "Angiopoietin 2" O15123 8 6499632-6563409 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 81.7;Endothelial cells: 182.2;Smooth muscle cells: 79.8" "Cancer enhanced" "Detected in all" "renal cancer: 12.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 8 "HMC-1: 17.9;HSkMC: 39.9;HUVEC TERT2: 62.6;WM-115: 22.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB011437, CAB017626" Approved "Secreted to blood" NA NA 3780000 110000 "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "CAB011437: , CAB017626: AB_1118956" "unprognostic (1.28e-1)" "prognostic unfavorable (7.99e-5)" "unprognostic (1.93e-2)" "unprognostic (1.23e-1)" "unprognostic (4.85e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.36e-5)" "unprognostic (1.66e-3)" "prognostic unfavorable (4.48e-4)" "unprognostic (2.94e-3)" "unprognostic (6.19e-3)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.52e-7)" "prognostic unfavorable (3.87e-4)" "unprognostic (1.12e-1)" "unprognostic (1.46e-2)" "unprognostic (6.44e-2)" 15.7 0.5 5.6 3.8 5.0 0.4 9.9 6.3 9.0 6.2 2.6 2.9 1.2 4.3 1.1 2.2 4.2 4.9 7.3 4.9 6.3 5.4 2.7 4.6 6.8 12.3 5.8 2.5 0.8 2.3 0.8 11.3 12.3 3.3 1.8 1.6 2.5 2.7 4.0 3.1 2.5 6.8 7.7 0.5 1.8 0.9 7.6 6.4 8.2 2.0 2.8 10.6 3.2 7.5 0.1 0.2 0.3 0.1 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.1 4.7 0.4 0.1 0.9 0.0 17.9 39.9 0.0 0.0 0.0 0.1 62.6 0.1 0.1 0.4 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.5 0.8 0.0 0.0 0.1 0.3 0.1 0.1 1.3 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.1 22.7 1.7 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.4 0.2 0.3 0.2 0.2 0.1 0.3 0.1 0.1 5.6 5.0 6.3 9.0 4.9 6.3 12.3 5.8 12.3 7.7 7.6 7.5 81.7 9.6 0.0 5.2 7.8 8.2 2.7 2.5 1.8 9.3 1.5 1.4 2.8 2.8 1.6 0.0 29.2 1.8 3.6 0.6 0.0 1.3 3.2 4.2 5.4 182.2 13.8 1.3 17.0 0.5 1.5 6.3 1.5 5.9 4.5 2.0 30.4 0.9 0.6 38.7 16.1 1.7 0.0 2.5 10.9 5.0 43.5 2.7 16.0 26.2 2.4 2.9 7.2 24.6 11.3 1.3 1.2 3.8 0.9 9.9 2.6 1.0 1.4 12.5 0.0 8.1 79.8 1.6 1.6 0.3 8.0 30.6 5.5 2.9 1.3 4.7 ANGPTL3 ANGPT5 ENSG00000132855 "Angiopoietin like 3" Q9Y5C1 1 62597520-62606313 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Lipid metabolism" Heparin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 675.7" "Group enriched" "Detected in some" 12 "Hepatocytes: 567.6;Proximal tubular cells: 272.5" "Cancer enriched" "Detected in some" 39 "liver cancer: 94.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA038097 Approved "Secreted to blood" NA NA 225000000 120000000 "Cluster 85: Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA038097: AB_10675628" "unprognostic (2.29e-1)" "unprognostic (8.01e-2)" "unprognostic (2.51e-1)" "unprognostic (4.06e-2)" "unprognostic (2.70e-1)" "unprognostic (1.25e-2)" "unprognostic (4.06e-2)" "unprognostic (1.56e-2)" "unprognostic (8.11e-3)" "unprognostic (6.85e-3)" "unprognostic (2.89e-2)" "unprognostic (1.20e-2)" "unprognostic (1.09e-2)" "unprognostic (3.08e-2)" "unprognostic (1.09e-2)" "unprognostic (5.38e-2)" "unprognostic (7.62e-2)" 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 53.0 675.7 0.0 0.0 0.2 0.2 0.1 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 4.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.1 0.1 0.1 0.2 0.2 0.1 0.2 0.2 0.4 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.3 11.5 0.0 5.5 0.0 0.0 0.0 0.0 33.2 0.0 0.0 0.1 0.1 0.7 0.0 16.0 0.1 0.2 0.1 0.0 2.6 0.3 0.0 0.0 9.7 567.6 0.1 0.0 0.1 0.0 0.0 16.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 272.5 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.9 0.1 0.0 0.0 ANK2 "CFAP87, FAP87, LQT4" ENSG00000145362 "Ankyrin 2" Q01484 4 112818032-113384221 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 165.7;retina: 191.2;skeletal muscle: 171.7;tongue: 150.5" "Group enriched" "Detected in many" 4 "Astrocytes: 1101.2;Bipolar cells: 376.6;Cone photoreceptor cells: 479.6;Excitatory neurons: 1282.0;Horizontal cells: 1431.8;Inhibitory neurons: 1060.7;Oligodendrocyte precursor cells: 497.1;Oligodendrocytes: 1351.0;Rod photoreceptor cells: 484.4" "Cancer enhanced" "Detected in many" "glioma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 29.2;ASC TERT1: 32.2;RH-30: 49.6;SH-SY5Y: 24.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008007, CAB015178, HPA035970" Enhanced Approved Supported "Plasma membrane" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB015178: AB_2242828, HPA008007: AB_2667965, HPA035970: AB_2674893" "unprognostic (8.33e-2)" "unprognostic (9.47e-2)" "unprognostic (1.33e-2)" "unprognostic (7.63e-2)" "unprognostic (2.73e-1)" "unprognostic (1.71e-1)" "unprognostic (1.54e-1)" "unprognostic (2.15e-2)" "unprognostic (1.23e-1)" "unprognostic (1.63e-1)" "unprognostic (1.79e-3)" "unprognostic (2.94e-2)" "prognostic unfavorable (2.41e-6)" "unprognostic (1.18e-2)" "unprognostic (3.16e-1)" "unprognostic (1.51e-3)" "unprognostic (2.04e-3)" 31.0 13.6 94.9 11.2 109.0 0.1 18.3 63.1 165.7 31.6 0.0 30.1 8.5 15.8 5.9 12.9 9.6 22.5 119.5 103.9 77.5 110.1 2.4 7.2 9.2 130.2 61.1 27.3 3.2 1.2 19.3 2.1 119.5 7.8 11.4 191.2 6.7 13.3 171.7 8.7 12.7 24.9 51.9 28.3 8.3 9.4 84.8 4.4 9.6 150.5 7.2 9.5 12.3 116.2 0.1 2.9 18.7 5.2 29.2 32.2 0.1 1.5 3.4 0.9 2.6 4.2 0.0 6.9 2.1 5.9 4.1 0.1 11.0 0.6 1.0 2.3 7.3 4.0 0.0 2.9 1.7 1.9 1.2 15.2 3.0 1.2 6.0 3.9 0.0 0.4 0.0 9.3 5.8 0.3 0.2 0.1 9.4 0.1 2.0 0.7 49.6 0.0 0.2 0.0 13.6 24.1 0.2 0.7 8.1 11.7 0.1 1.1 0.0 4.7 2.2 0.4 3.0 6.8 1.8 0.9 20.1 0.6 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.9 109.0 63.1 165.7 103.9 77.5 130.2 61.1 119.5 51.9 84.8 116.2 6.9 0.0 3.9 1101.2 1.1 10.5 0.0 0.0 1.8 376.6 0.2 0.6 188.5 0.0 1.3 20.2 479.6 0.1 0.0 0.0 15.6 0.0 111.2 36.4 6.0 6.4 66.0 0.0 1282.0 1.6 0.1 79.0 2.0 7.2 1.3 81.8 0.0 0.4 1.0 1431.8 1060.7 0.4 8.2 0.0 19.7 49.8 36.4 2.9 17.8 90.9 0.6 44.5 0.0 497.1 1351.0 0.1 5.0 30.1 0.9 0.4 0.1 127.9 0.8 484.4 6.6 24.3 26.5 2.3 1.5 0.8 9.5 0.0 1.9 2.6 0.3 0.2 ANKRD13B FLJ25555 ENSG00000198720 "Ankyrin repeat domain 13B" Q86YJ7 17 29589769-29614761 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 27.4;Endometrial stromal cells: 24.2;Excitatory neurons: 19.4;Horizontal cells: 16.8;Late spermatids: 44.7;Oligodendrocytes: 17.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 52.0;SH-SY5Y: 57.6;SK-BR-3: 48.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051886, HPA063748" Uncertain Supported Vesicles NA NA "Cluster 43: Testis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA051886: AB_2681652, HPA063748: AB_2685112" "unprognostic (1.61e-1)" "unprognostic (2.01e-1)" "unprognostic (1.27e-1)" "unprognostic (1.66e-2)" "unprognostic (1.53e-1)" "unprognostic (2.45e-1)" "unprognostic (3.10e-4)" "unprognostic (1.84e-1)" "unprognostic (1.84e-1)" "unprognostic (1.03e-2)" "prognostic favorable (7.58e-4)" "unprognostic (3.94e-2)" "prognostic unfavorable (5.92e-6)" "unprognostic (9.93e-2)" "unprognostic (1.18e-1)" "unprognostic (3.94e-2)" "unprognostic (5.36e-3)" 12.0 3.7 12.5 1.7 14.3 0.7 7.5 11.9 15.9 16.3 0.0 10.2 0.8 13.6 0.8 6.5 12.0 3.7 10.3 13.9 6.2 2.8 1.2 5.5 1.6 13.4 9.4 15.1 3.7 1.6 14.6 0.9 10.4 7.7 0.6 2.0 4.3 1.8 9.6 7.5 4.5 2.9 7.2 2.6 4.9 18.9 10.8 0.9 5.8 1.3 0.3 10.0 11.6 22.9 6.6 11.5 13.3 35.4 8.2 8.0 5.1 2.0 1.2 1.4 2.7 6.1 1.4 7.4 6.4 2.8 4.9 24.3 7.2 7.8 0.2 14.8 23.5 2.3 22.3 5.3 3.5 2.4 4.6 7.9 10.2 2.2 5.8 6.4 10.1 12.8 6.0 6.1 1.9 5.9 16.0 7.5 11.4 6.8 9.7 33.4 9.5 23.4 3.0 2.2 52.0 57.6 3.9 48.0 4.3 1.2 7.4 4.4 6.7 7.4 7.2 5.2 7.2 11.4 15.7 9.2 5.2 12.1 4.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 14.3 11.9 15.9 13.9 6.2 13.4 9.4 10.4 7.2 10.8 22.9 2.6 0.0 0.0 6.8 0.1 1.7 1.0 0.7 3.4 4.5 1.8 2.7 2.3 0.0 0.4 0.0 2.1 0.1 0.6 0.6 1.9 1.6 27.4 0.9 24.2 2.4 3.0 1.7 19.4 0.6 0.2 5.5 2.6 1.0 0.0 3.8 1.4 0.6 0.1 16.8 14.6 0.8 0.0 0.3 1.6 44.7 14.6 0.3 0.0 0.0 0.0 1.8 0.0 11.1 17.8 0.5 0.0 7.5 0.5 3.2 0.1 0.2 0.0 5.2 0.0 2.4 2.5 6.0 4.7 2.6 1.7 0.1 0.7 1.0 1.1 1.5 ANKRD35 FLJ25124 ENSG00000198483 "Ankyrin repeat domain 35" Q8N283 1 145866560-145885866 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 60.8" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 56.4;Fibroblasts: 31.2;Leydig cells: 36.4;Muller glia cells: 57.7;Peritubular cells: 50.8;Skeletal myocytes: 29.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC TERT1: 9.6;THP-1: 6.8;TIME: 8.4;U-87 MG: 8.3;U-937: 7.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035453 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Nucleoplasm "HPA035453: AB_10672864" "prognostic favorable (9.35e-4)" "prognostic favorable (2.90e-4)" "unprognostic (2.07e-1)" "unprognostic (7.39e-3)" "unprognostic (1.77e-2)" "unprognostic (1.02e-2)" "unprognostic (3.27e-1)" "unprognostic (3.58e-2)" "unprognostic (3.03e-1)" "unprognostic (1.79e-1)" "unprognostic (2.98e-1)" "unprognostic (5.86e-2)" "unprognostic (9.29e-10)" "unprognostic (8.80e-3)" "unprognostic (2.18e-1)" "unprognostic (5.92e-2)" "unprognostic (8.69e-3)" 4.0 1.3 8.2 1.1 7.9 0.3 4.6 7.6 9.7 20.6 6.4 6.0 0.5 5.8 1.4 24.7 6.6 1.3 2.9 7.5 8.6 0.8 2.5 2.3 0.4 8.7 9.5 4.4 0.7 0.0 2.0 0.1 8.5 6.6 0.8 1.3 11.4 2.7 8.2 60.8 2.5 2.1 8.4 0.5 3.9 1.6 9.0 0.5 1.7 3.8 6.7 7.3 20.6 7.6 0.1 0.0 0.0 0.0 2.2 9.6 0.2 1.4 3.6 0.4 1.2 0.4 0.0 0.0 0.3 1.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 1.1 2.9 0.1 3.3 0.4 0.3 0.0 0.1 0.4 0.0 0.0 0.0 2.2 0.0 0.0 3.9 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 8.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 8.3 7.5 0.0 0.0 2.1 0.0 0.7 0.8 0.1 0.0 0.3 1.1 0.3 0.0 0.2 0.7 0.1 0.7 0.2 0.5 0.7 0.7 8.2 7.9 7.6 9.7 7.5 8.6 8.7 9.5 8.5 8.4 9.0 7.6 1.6 0.0 0.0 6.8 0.3 4.6 16.8 10.2 0.0 1.1 6.3 13.5 1.5 2.8 9.5 1.8 0.0 0.1 2.2 0.0 0.0 0.0 3.5 56.4 10.9 1.3 0.0 2.7 5.6 0.4 0.1 31.2 0.5 17.2 19.1 0.0 2.2 13.9 11.0 0.0 2.1 0.0 14.2 1.2 4.6 5.9 36.4 1.1 5.4 1.0 1.1 57.7 5.2 3.0 0.6 0.1 0.0 50.8 0.4 5.3 0.0 0.1 9.8 2.7 0.0 29.5 6.4 0.1 1.0 10.4 12.4 0.3 5.5 1.1 0.0 13.6 ANKRD46 ENSG00000186106 "Ankyrin repeat domain 46" Q86W74 8 100509752-100559784 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Horizontal cells: 67.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013758 Approved Approved Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 62: Horizontal cells - Visual perception" Cytosol "HPA013758: AB_10962626" "unprognostic (3.71e-3)" "unprognostic (9.01e-2)" "unprognostic (2.03e-1)" "unprognostic (2.22e-2)" "unprognostic (9.82e-2)" "unprognostic (1.16e-1)" "unprognostic (2.63e-1)" "unprognostic (8.84e-2)" "unprognostic (4.79e-2)" "unprognostic (3.56e-1)" "unprognostic (2.98e-2)" "unprognostic (1.51e-1)" "unprognostic (8.08e-3)" "unprognostic (5.29e-2)" "unprognostic (1.82e-1)" "unprognostic (1.81e-2)" "unprognostic (6.29e-3)" 19.2 38.7 29.1 8.4 30.2 2.2 14.6 25.1 33.6 15.1 15.6 9.2 10.2 12.7 16.3 12.7 11.4 7.7 20.1 30.1 25.8 32.7 41.6 10.7 9.9 22.3 22.2 22.6 18.5 16.1 10.3 20.8 24.4 13.5 9.1 35.2 17.1 13.2 62.2 11.2 11.0 12.4 24.9 11.1 11.6 8.3 24.0 15.4 20.0 36.2 10.9 9.5 9.9 28.7 10.0 12.2 17.9 10.1 13.6 8.0 20.0 12.8 5.8 9.6 8.1 17.8 5.9 31.2 23.3 4.4 3.1 7.5 18.5 9.5 10.1 11.2 16.3 39.0 6.4 14.1 7.7 9.3 4.7 5.8 17.1 6.1 10.2 10.3 11.9 21.4 20.8 9.9 9.3 11.4 43.3 16.8 13.1 25.6 9.0 33.1 6.0 21.0 14.1 10.6 19.8 20.1 5.5 9.9 8.5 21.5 14.8 15.7 9.0 4.4 4.9 6.5 5.1 23.0 23.8 25.7 4.8 29.6 7.2 16.4 7.3 7.6 14.4 3.7 17.1 12.7 13.5 12.4 9.6 11.1 17.5 15.2 1.8 16.9 6.8 8.8 13.8 10.9 29.1 30.2 25.1 33.6 30.1 25.8 22.3 22.2 24.4 24.9 24.0 28.7 11.5 6.4 3.9 17.9 14.2 10.8 11.3 9.0 19.4 30.1 10.7 7.4 13.1 12.8 4.8 22.0 18.8 32.1 12.2 5.7 29.4 8.3 1.2 4.6 6.7 12.5 7.3 12.2 41.5 6.0 14.1 11.9 9.7 4.7 4.5 13.8 21.8 34.6 11.4 67.3 36.9 7.6 2.0 6.7 9.3 2.2 21.1 4.0 10.6 24.4 8.1 46.4 10.3 24.1 23.4 3.3 9.1 26.4 13.8 10.5 20.3 61.8 6.5 31.5 26.3 15.1 12.8 14.4 17.2 13.9 14.2 23.4 9.3 11.9 8.5 9.6 ANO6 "DKFZp313M0720, TMEM16F" ENSG00000177119 "Anoctamin 6" Q4KMQ2 12 45215987-45482280 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Lipid transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038958 Approved Approved "Plasma membrane,Cytosol" NA NA 47000 "Cluster 14: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 32: U-937 - Innate immune response" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane, Cytosol" "HPA038958: AB_10672835" "prognostic unfavorable (7.56e-5)" "prognostic unfavorable (3.82e-4)" "unprognostic (2.16e-1)" "unprognostic (1.75e-2)" "unprognostic (1.29e-1)" "unprognostic (9.82e-3)" "unprognostic (7.43e-2)" "unprognostic (3.01e-3)" "unprognostic (7.55e-2)" "unprognostic (2.84e-3)" "unprognostic (1.41e-3)" "unprognostic (3.02e-1)" "unprognostic (2.68e-2)" "unprognostic (1.26e-3)" "unprognostic (1.26e-1)" "unprognostic (4.20e-2)" "unprognostic (1.28e-1)" 86.4 25.9 7.4 16.8 8.0 9.8 27.5 7.9 8.4 28.9 13.8 29.9 36.2 38.9 25.6 25.0 27.2 31.6 27.7 7.2 10.5 36.2 56.9 40.2 13.4 10.4 8.5 56.6 25.3 58.8 6.9 50.5 10.1 29.9 15.0 3.6 25.4 37.1 56.0 12.0 51.4 48.4 9.0 16.0 13.8 11.8 9.1 24.9 13.2 46.3 12.8 35.0 16.0 9.3 41.5 44.3 25.7 35.4 119.1 61.7 97.4 57.4 72.5 38.4 36.3 71.9 61.5 21.1 52.2 92.0 34.9 54.0 24.1 32.3 45.6 31.4 16.9 25.0 17.8 62.1 37.8 39.5 19.4 51.7 31.9 33.0 48.7 95.4 52.6 44.5 19.3 34.0 42.7 11.2 41.5 13.2 28.6 0.0 18.0 23.4 33.3 24.4 36.9 63.1 11.7 39.9 59.9 36.8 27.9 67.7 43.3 62.8 70.6 41.2 26.1 41.8 29.3 18.3 21.5 25.8 37.3 122.8 33.4 3.1 5.9 1.4 2.4 6.9 2.5 1.4 2.2 2.0 5.5 1.2 2.0 1.3 0.6 2.3 7.1 2.7 3.0 4.2 7.4 8.0 7.9 8.4 7.2 10.5 10.4 8.5 10.1 9.0 9.1 9.3 65.1 60.9 11.8 54.9 10.0 30.5 20.3 27.7 23.3 1.1 23.0 18.7 23.4 30.0 21.5 18.4 0.0 34.0 14.5 2.5 3.9 38.4 1.3 13.3 32.1 37.5 8.4 8.0 49.8 37.4 28.0 44.2 21.4 26.0 12.7 20.2 52.5 88.3 19.9 0.0 49.0 11.5 12.2 56.3 22.9 3.5 51.3 46.0 17.8 68.4 29.1 8.2 15.5 110.6 3.0 73.3 10.0 40.6 12.2 29.5 70.3 23.4 16.5 0.3 39.5 45.9 52.1 3.5 4.3 25.1 22.0 24.6 17.3 6.7 14.6 30.5 ANO9 "PIG5, TMEM16J, TP53I5" ENSG00000185101 "Anoctamin 9" A1A5B4 11 417933-442011 "Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 34.2;skin 1: 27.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 81.0;Intestinal goblet cells: 50.5;Paneth cells: 50.5;Proximal enterocytes: 87.7;Undifferentiated cells: 45.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 26.1" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 48 "B-cells: 2.1;NK-cells: 4.1;T-cells: 8.2" "Cell line enhanced" "Detected in some" "BEWO: 9.2;CAPAN-2: 29.5;HaCaT: 16.8;RPMI-8226: 20.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039948, HPA040112" Approved Uncertain "Golgi apparatus" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "HPA039948: AB_2676765, HPA040112: " "unprognostic (3.62e-3)" "unprognostic (2.83e-2)" "unprognostic (4.68e-2)" "unprognostic (1.62e-1)" "unprognostic (1.41e-2)" "unprognostic (8.93e-2)" "unprognostic (6.98e-2)" "unprognostic (8.94e-3)" "unprognostic (1.39e-1)" "unprognostic (2.28e-3)" "unprognostic (1.54e-1)" "unprognostic (7.94e-2)" "unprognostic (1.91e-2)" "unprognostic (1.18e-2)" "unprognostic (2.08e-1)" "unprognostic (3.92e-1)" "prognostic favorable (8.81e-4)" 0.7 0.1 0.0 7.0 0.0 2.2 1.7 0.0 0.0 1.1 0.2 16.0 34.2 0.5 7.0 6.3 1.2 2.0 0.1 0.0 0.0 3.7 0.3 2.9 12.0 0.0 0.0 0.1 6.5 0.7 1.3 0.1 0.0 2.9 9.1 0.0 3.0 0.7 0.0 27.8 30.0 0.8 0.0 4.7 7.0 0.2 0.0 9.0 2.4 0.1 8.7 2.4 3.4 0.0 2.7 0.6 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 3.1 29.5 1.9 1.4 0.0 0.1 16.8 0.0 7.0 0.0 2.1 0.0 0.0 0.6 5.1 0.0 0.4 0.0 0.0 5.6 0.0 1.2 0.1 0.0 4.5 0.1 1.9 0.0 3.8 0.5 0.1 0.0 6.0 0.0 0.1 0.0 20.6 5.1 4.4 1.6 0.0 0.3 7.3 0.0 0.2 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 5.5 2.1 6.5 3.3 0.0 0.8 3.7 2.8 0.0 4.1 0.0 0.0 8.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 9.7 0.3 9.1 5.2 4.6 15.3 6.2 0.0 5.5 3.9 2.4 8.6 9.1 3.7 0.0 0.3 3.0 81.0 0.0 10.5 0.8 4.9 1.0 0.8 15.5 0.0 0.3 6.5 3.7 0.6 29.0 11.0 0.0 0.0 0.7 0.3 0.4 0.0 0.2 50.5 14.2 0.3 1.9 0.1 0.0 1.2 3.6 0.0 1.3 0.0 0.0 0.0 0.0 9.0 50.5 0.0 5.0 2.7 87.7 3.7 9.2 0.0 0.0 0.1 1.0 0.2 0.2 7.0 6.3 0.1 12.8 0.0 45.2 5.7 ANPEP "CD13, gp150, LAP1, p150, PEPN" ENSG00000166825 "Alanyl aminopeptidase, membrane" P15144 15 89784895-89815401 "CD markers, Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Aminopeptidase, Developmental protein, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 2384.1;pancreas: 675.0" "Cell type enriched" "Detected in many" 14 "Proximal enterocytes: 6315.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 5 "cerebral cortex: 9.2;thalamus: 17.4" "Immune cell enriched" "Detected in many" 4 "neutrophil: 227.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 227.1" "Cell line enhanced" "Detected in many" "ASC diff: 613.7;ASC TERT1: 764.2;BJ: 738.4;BJ hTERT+: 1135.6;fHDF/TERT166: 703.8;HMC-1: 660.3;HSkMC: 670.0;HUVEC TERT2: 874.8;TIME: 815.1;U-2197: 891.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "spinal cord: 14.8" "CAB002417, HPA004625" Enhanced Supported "Plasma membrane" NA NA 1200000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "CAB002417: AB_563491, HPA004625: AB_2667199" "unprognostic (6.31e-2)" "unprognostic (7.94e-3)" "unprognostic (6.91e-2)" "unprognostic (2.16e-1)" "unprognostic (2.50e-1)" "unprognostic (1.13e-1)" "unprognostic (2.23e-2)" "unprognostic (1.89e-1)" "unprognostic (2.50e-1)" "unprognostic (7.73e-2)" "unprognostic (5.28e-3)" "unprognostic (3.96e-1)" "unprognostic (4.04e-3)" "unprognostic (3.20e-2)" "unprognostic (2.01e-2)" "unprognostic (4.61e-3)" "unprognostic (1.99e-2)" 55.4 7.0 1.6 36.6 1.6 103.4 55.9 1.3 9.2 41.4 3.4 266.8 2384.1 3.6 1.7 4.8 8.0 120.3 6.9 1.3 1.5 249.7 271.8 34.3 12.8 1.5 2.1 1.9 675.0 0.8 1.9 33.1 2.5 94.0 59.9 0.0 42.1 5.5 2.5 32.5 1970.6 29.7 1.3 25.9 8.0 2.0 17.4 7.1 8.2 3.8 4.7 16.8 15.0 1.2 0.1 45.6 0.0 0.5 613.7 764.2 6.2 738.4 1135.6 95.3 81.6 5.8 0.4 0.2 8.4 703.8 0.0 0.6 5.6 0.2 38.6 0.1 0.1 137.3 4.6 122.8 352.0 11.4 660.3 670.0 1.4 302.3 0.3 4.4 874.8 0.0 3.8 0.8 37.8 0.1 0.6 355.4 1.9 0.0 49.9 0.3 0.1 9.5 449.2 0.0 1.2 7.2 0.1 1.3 0.1 1.8 0.5 72.1 815.1 385.3 0.6 891.4 0.1 0.4 0.1 0.1 0.9 0.9 20.5 22.2 56.3 41.1 0.1 27.4 0.0 0.2 0.0 0.0 26.2 0.2 0.0 0.0 227.1 0.0 49.7 0.7 0.0 25.7 1.6 1.6 1.3 9.2 1.3 1.5 1.5 2.1 2.5 1.3 17.4 1.2 2.4 0.0 3.0 0.0 5.2 9.9 2.8 1.4 0.6 0.0 35.7 12.8 1.2 391.7 19.7 20.2 0.0 13.0 0.7 429.8 43.0 15.4 0.2 0.5 10.1 8.4 3.0 6.6 0.3 386.2 16.3 31.0 0.0 0.4 24.1 0.3 79.2 192.4 37.5 0.0 0.3 199.6 2.0 54.1 63.2 0.2 2.8 71.9 3.6 0.0 38.3 0.0 0.0 0.0 0.1 75.5 316.9 1.5 2.1 20.9 6315.2 435.0 3.3 0.0 26.3 0.8 8.1 0.3 0.5 0.2 5.8 6.4 3.7 187.8 290.9 1.4 ANXA2R "AXIIR, C5orf39" ENSG00000177721 "Annexin A2 receptor" Q3ZCQ2 5 43039233-43043170 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.8;lymphoid tissue: 26.1" "Cell type enhanced" "Detected in many" "Adipocytes: 32.2;B-cells: 23.8;dendritic cells: 36.4;Endothelial cells: 24.8;Hepatic stellate cells: 38.2;NK-cells: 47.4;T-cells: 66.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "gdT-cell: 53.9;MAIT T-cell: 63.5;memory B-cell: 34.3;memory CD4 T-cell: 56.1;memory CD8 T-cell: 59.9;naive B-cell: 32.9;naive CD4 T-cell: 96.3;naive CD8 T-cell: 72.1;NK-cell: 24.8;T-reg: 66.5" "Group enriched" "Detected in all" 6 "B-cells: 34.3;NK-cells: 24.8;T-cells: 96.3" "Cell line enhanced" "Detected in many" "HSkMC: 27.7;JURKAT: 33.1;MOLT-4: 30.0;REH: 30.9;U-937: 117.7" HPA051482 Uncertain Approved "Nucleoplasm,Cytosol,Cytoplasmic bodies" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Cytosol, Cytoplasmic bodies" "HPA051482: AB_2681500" "unprognostic (3.38e-2)" "unprognostic (2.00e-3)" "unprognostic (1.21e-2)" "unprognostic (1.92e-2)" "unprognostic (1.40e-2)" "unprognostic (3.92e-3)" "unprognostic (5.65e-3)" "unprognostic (1.03e-1)" "unprognostic (1.87e-1)" "unprognostic (8.14e-2)" "unprognostic (2.13e-2)" "unprognostic (4.34e-1)" "prognostic unfavorable (6.36e-8)" "unprognostic (2.68e-1)" "unprognostic (2.77e-1)" "unprognostic (2.68e-1)" "unprognostic (1.68e-1)" 4.7 1.3 3.2 12.1 3.2 19.8 3.9 3.0 3.8 3.5 3.5 2.5 3.3 2.4 1.7 1.8 3.3 3.5 2.9 2.8 2.9 2.0 1.3 4.6 26.1 3.4 3.3 1.2 0.8 0.6 1.1 3.2 3.2 2.7 2.7 0.1 1.7 1.2 2.5 2.1 8.2 2.1 3.5 15.8 3.3 1.5 3.3 25.2 2.7 3.0 17.2 3.2 3.8 4.0 2.1 2.1 1.6 1.2 2.6 8.0 0.4 0.5 0.3 0.5 0.6 3.9 1.9 6.8 6.5 1.6 2.2 0.8 5.0 0.5 0.5 13.3 4.0 2.2 5.9 1.8 4.1 2.6 0.8 27.7 0.2 2.4 0.2 0.1 16.2 33.1 1.5 8.9 2.1 3.1 30.0 4.1 0.0 1.7 14.8 30.9 3.6 3.9 0.7 1.1 5.7 0.0 2.7 0.7 0.7 0.2 0.7 4.9 9.9 0.5 0.0 0.8 2.5 4.4 6.7 3.3 3.6 117.7 1.4 5.6 3.5 1.7 53.9 2.5 63.5 34.3 56.1 59.9 3.5 32.9 96.3 72.1 3.2 24.8 8.1 5.2 66.5 26.6 3.2 3.2 3.0 3.8 2.8 2.9 3.4 3.3 3.2 3.5 3.3 4.0 32.2 0.0 9.9 0.0 23.8 3.7 1.4 0.3 2.2 0.1 1.9 2.2 1.3 4.3 1.5 0.0 0.0 0.4 36.4 0.5 0.0 0.1 4.0 1.1 5.0 24.8 1.8 8.2 0.0 0.0 1.1 7.2 1.5 0.8 15.2 4.1 38.2 1.4 8.7 0.0 0.0 0.1 2.0 18.2 5.6 1.5 1.5 7.5 7.2 0.0 7.1 0.2 47.4 0.0 0.0 0.1 0.0 0.4 7.8 1.2 1.0 0.4 2.0 0.0 0.0 3.4 3.7 0.7 1.6 1.2 2.3 0.4 66.0 0.3 0.5 1.4 AOC3 "HPAO, VAP-1, VAP1" ENSG00000131471 "Amine oxidase copper containing 3" Q16853 17 42851184-42858130 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 422.8" "Group enriched" "Detected in many" 4 "Adipocytes: 58.2;Peritubular cells: 74.9;Sertoli cells: 118.3;Smooth muscle cells: 93.0;Theca cells: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 17 "ASC diff: 307.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA000980, CAB025797" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted - unknown location" NA NA 240000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "Golgi apparatus" "CAB025797: , HPA000980: AB_1078170" "unprognostic (2.20e-1)" "unprognostic (4.49e-2)" "prognostic unfavorable (3.68e-4)" "unprognostic (2.97e-2)" "unprognostic (1.17e-1)" "unprognostic (2.64e-1)" "unprognostic (2.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.48e-1)" "unprognostic (4.00e-2)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (1.79e-5)" "unprognostic (5.61e-2)" "unprognostic (1.67e-1)" "unprognostic (8.39e-2)" "prognostic unfavorable (6.98e-4)" 422.8 48.4 2.6 31.9 3.2 1.4 169.2 2.5 4.2 52.8 2.7 210.8 17.3 95.1 33.5 88.0 84.8 50.7 50.2 2.9 2.5 24.1 19.1 218.6 12.4 2.5 2.5 26.5 12.0 8.4 5.4 28.0 2.6 59.1 41.0 1.7 14.7 103.6 17.8 24.6 57.6 144.8 2.3 21.4 66.6 12.8 2.4 5.9 28.2 22.9 3.9 142.1 50.9 2.5 0.1 1.5 0.2 1.0 307.5 0.3 5.0 0.3 0.1 0.2 0.8 0.9 0.0 0.7 0.7 0.1 0.2 0.5 0.8 0.2 0.8 1.5 5.7 0.4 0.5 18.4 0.8 0.3 1.0 3.3 1.0 0.3 0.8 0.0 0.2 2.2 0.3 1.7 0.6 0.2 0.2 1.4 0.7 0.1 0.4 0.7 0.8 3.0 0.1 2.2 0.3 0.4 0.0 0.2 2.0 2.2 0.1 0.1 0.0 0.3 2.7 1.2 0.4 4.8 5.9 0.6 0.4 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.6 3.2 2.5 4.2 2.9 2.5 2.5 2.5 2.6 2.3 2.4 2.5 58.2 3.2 6.0 0.0 0.5 2.9 0.1 0.0 2.2 0.0 1.1 2.2 9.5 0.0 1.9 0.0 0.0 0.1 0.4 0.1 0.0 0.2 4.5 0.8 2.3 12.3 0.0 0.0 0.4 0.2 0.1 11.3 0.0 1.4 1.3 2.1 20.7 0.2 1.4 0.0 0.3 0.1 0.0 1.4 2.7 2.6 3.4 0.9 3.6 3.7 0.0 0.2 0.0 0.0 0.1 0.2 0.0 74.9 0.0 0.4 0.1 1.4 1.0 0.4 118.3 2.6 93.0 1.1 1.3 0.7 1.8 0.3 0.6 74.6 0.1 0.3 AP1M2 "AP1-mu2, HSMU1B, mu2" ENSG00000129354 "Adaptor related protein complex 1 subunit mu 2" Q9Y6Q5 19 10572671-10587315 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 162.0;Proximal tubular cells: 373.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 4.3;neutrophil: 7.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 7.6" "Cell line enhanced" "Detected in many" "CACO-2: 172.8;Hep G2: 313.8;MCF7: 268.3;OE19: 156.7;RT4: 164.9;U-2 OS: 166.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA054999 Supported Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA054999: AB_2682666" "unprognostic (8.31e-2)" "unprognostic (2.38e-1)" "unprognostic (1.87e-1)" "prognostic favorable (2.07e-4)" "unprognostic (2.07e-1)" "unprognostic (7.76e-2)" "unprognostic (2.11e-3)" "unprognostic (4.83e-2)" "unprognostic (1.93e-1)" "unprognostic (2.49e-2)" "unprognostic (2.65e-1)" "unprognostic (2.23e-2)" "prognostic favorable (3.73e-6)" "unprognostic (1.80e-2)" "unprognostic (8.10e-2)" "unprognostic (2.05e-2)" "unprognostic (1.06e-1)" 3.4 0.1 0.8 6.4 0.3 0.9 32.9 0.6 0.8 27.1 0.3 67.1 64.0 6.6 61.8 51.9 46.6 22.7 0.4 0.5 0.4 76.3 1.5 19.2 0.4 0.7 0.6 0.3 55.9 62.4 34.8 16.2 0.4 30.8 63.4 0.1 41.5 24.0 0.3 42.1 54.8 3.0 0.3 0.6 59.1 9.6 0.7 4.2 58.8 0.3 9.5 23.4 19.1 0.6 144.2 71.1 0.4 10.4 0.0 0.0 65.0 0.2 0.0 2.3 1.6 172.8 82.1 0.4 64.7 1.2 43.4 97.6 0.1 109.0 3.2 0.6 1.0 6.7 48.5 313.8 1.3 0.3 0.8 0.2 81.6 3.9 0.1 5.0 0.0 0.4 0.3 0.6 1.2 268.3 0.6 1.8 31.4 156.7 0.0 2.4 9.3 0.7 2.7 164.9 67.3 0.2 0.0 120.0 0.6 34.6 123.3 0.4 0.0 0.4 166.7 0.9 2.2 0.4 0.9 1.4 0.2 0.4 0.2 4.3 0.4 2.7 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 7.6 0.0 1.4 0.2 0.0 2.7 0.8 0.3 0.6 0.8 0.5 0.4 0.7 0.6 0.4 0.3 0.7 0.6 0.4 28.9 34.8 0.0 1.9 6.9 19.2 68.9 13.1 0.0 49.3 30.0 0.5 47.1 64.2 86.5 0.0 123.0 0.5 112.2 137.0 141.3 43.4 52.4 5.4 1.7 74.4 0.0 0.3 115.8 101.0 1.5 73.4 57.7 2.5 0.0 0.7 0.0 9.8 0.0 0.2 95.5 97.6 0.8 0.0 19.9 1.5 2.6 3.6 0.0 1.7 0.0 0.0 0.0 0.2 130.2 125.6 0.7 0.0 37.6 162.0 373.6 61.5 0.0 0.0 0.0 6.2 16.9 4.1 39.1 13.1 66.1 2.8 0.0 131.4 48.3 AP3M2 "AP47B, CLA20" ENSG00000070718 "Adaptor related protein complex 3 subunit mu 2" P53677 8 42152946-42171673 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014876, HPA045591, HPA048380" Approved NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "CAB014876: , HPA045591: AB_2679377, HPA048380: AB_2680379" "unprognostic (5.53e-2)" "unprognostic (2.26e-2)" "unprognostic (3.50e-2)" "prognostic unfavorable (3.46e-4)" "unprognostic (3.33e-1)" "unprognostic (1.14e-1)" "unprognostic (2.02e-2)" "unprognostic (8.20e-2)" "unprognostic (1.13e-1)" "unprognostic (2.47e-1)" "unprognostic (3.68e-1)" "unprognostic (4.80e-2)" "unprognostic (3.61e-2)" "unprognostic (2.69e-1)" "unprognostic (4.32e-1)" "unprognostic (8.04e-2)" "prognostic favorable (2.38e-4)" 9.1 11.3 26.0 8.0 27.0 11.2 8.8 18.5 27.4 9.2 14.4 8.5 7.2 10.5 13.0 7.0 16.4 10.5 14.1 27.9 25.7 12.4 4.6 12.7 12.4 22.9 21.4 9.5 6.5 22.7 13.3 20.6 24.2 10.3 8.7 41.9 6.2 11.5 8.9 12.6 7.8 9.9 20.8 10.4 7.0 23.6 26.9 8.3 13.5 10.6 10.4 9.9 8.1 21.2 20.6 20.8 18.2 21.4 16.2 15.9 4.0 23.5 23.3 22.0 25.7 11.7 24.4 12.3 14.7 13.5 24.8 23.9 28.6 14.8 28.4 17.0 26.9 23.4 17.8 8.1 14.7 10.1 13.4 14.5 25.1 24.0 13.6 30.5 15.0 35.1 28.5 11.3 20.2 9.7 30.0 11.9 20.4 25.0 14.5 28.6 34.7 13.2 16.8 24.0 25.9 18.6 14.4 7.2 26.1 18.8 21.2 6.4 9.6 13.4 19.2 20.0 10.9 9.6 19.5 11.2 18.8 1.4 37.8 2.9 1.9 1.5 7.5 2.7 9.7 4.7 15.5 8.1 4.2 3.0 14.4 5.7 2.3 7.7 2.8 6.8 5.9 5.0 26.0 27.0 18.5 27.4 27.9 25.7 22.9 21.4 24.2 20.8 26.9 21.2 16.2 12.8 3.3 16.6 13.6 17.5 20.3 8.0 9.1 35.9 6.9 7.4 17.0 1.5 9.3 14.7 39.6 7.0 21.3 2.6 5.9 12.9 59.8 15.7 11.6 18.1 3.0 10.8 26.2 7.4 4.8 11.5 6.6 11.1 3.8 12.1 18.5 4.3 6.6 35.3 33.6 3.0 16.2 2.1 10.1 70.1 5.3 6.5 37.4 14.0 13.5 19.6 11.3 15.1 16.0 16.3 1.8 9.1 17.1 8.9 0.9 6.8 18.8 37.1 19.7 8.1 15.0 26.8 45.0 6.6 19.7 2.9 41.5 11.0 4.3 15.4 AP3S2 sigma3b ENSG00000157823 "Adaptor related protein complex 3 subunit sigma 2" P59780 15 89830599-89894638 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049270 Uncertain Approved Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA049270: AB_2680696" "unprognostic (1.46e-1)" "unprognostic (1.60e-2)" "unprognostic (1.18e-2)" "unprognostic (1.12e-1)" "unprognostic (2.28e-1)" "unprognostic (2.68e-1)" "unprognostic (3.78e-2)" "unprognostic (5.27e-2)" "unprognostic (3.03e-1)" "unprognostic (7.59e-2)" "unprognostic (1.22e-1)" "unprognostic (4.31e-2)" "prognostic favorable (5.55e-16)" "unprognostic (7.97e-2)" "unprognostic (1.13e-1)" "unprognostic (2.43e-1)" "unprognostic (8.67e-3)" 24.2 20.3 15.1 11.2 15.8 10.4 19.4 14.9 18.1 17.3 13.3 19.3 10.9 13.0 16.3 20.7 17.3 17.5 30.7 15.0 17.0 36.5 40.5 16.3 12.9 16.0 18.4 20.0 19.0 32.6 9.0 18.5 18.4 15.3 19.2 44.0 13.5 21.4 44.8 8.7 10.2 18.0 15.0 12.6 10.0 12.5 16.7 20.1 26.2 45.2 17.7 15.3 6.8 16.7 13.5 60.6 33.4 35.6 66.7 45.6 28.0 58.8 75.2 74.3 59.7 26.0 34.8 12.1 51.3 39.1 48.9 31.0 57.4 33.1 58.3 51.2 29.0 37.3 25.4 33.6 28.1 16.1 22.3 30.9 40.4 20.7 41.6 40.6 38.8 30.8 29.1 32.8 48.0 27.7 27.6 8.7 37.2 68.5 11.6 15.9 33.8 25.0 42.1 35.9 25.5 22.3 69.4 43.1 40.4 69.8 26.9 14.1 16.3 40.0 19.2 62.1 19.6 28.3 94.5 28.9 35.8 18.7 24.1 6.3 16.6 7.8 5.0 15.4 7.8 4.5 7.2 7.4 11.6 6.3 5.7 4.0 16.1 8.3 19.9 7.4 8.4 10.6 15.1 15.8 14.9 18.1 15.0 17.0 16.0 18.4 18.4 15.0 16.7 16.7 5.9 12.8 15.4 0.0 5.9 3.3 4.0 6.0 5.2 22.0 8.0 5.7 18.2 10.0 11.2 5.5 35.5 8.9 6.1 34.4 9.8 13.4 3.1 5.9 10.8 7.2 14.4 5.0 0.0 16.1 4.2 9.0 8.2 7.1 8.2 15.4 8.9 17.0 6.4 18.5 0.0 11.4 2.0 12.0 6.4 3.2 7.2 9.7 8.8 0.0 16.9 17.3 9.2 0.0 0.0 13.4 16.4 7.5 8.6 5.8 15.8 13.7 9.8 30.6 0.0 6.1 6.0 11.6 8.3 6.1 2.8 6.4 6.2 28.5 15.2 4.2 AP4M1 "MU-4, MU-ARP2, SPG50" ENSG00000221838 "Adaptor related protein complex 4 subunit mu 1" O00189 7 100101549-100110345 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 95.9;Spermatocytes: 84.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066774 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA066774: AB_2685718" "unprognostic (6.40e-2)" "unprognostic (3.28e-1)" "unprognostic (1.78e-1)" "unprognostic (1.14e-1)" "unprognostic (7.22e-2)" "unprognostic (2.24e-3)" "prognostic unfavorable (7.63e-5)" "unprognostic (1.58e-2)" "unprognostic (6.98e-3)" "unprognostic (1.73e-1)" "unprognostic (3.05e-2)" "unprognostic (7.18e-2)" "prognostic unfavorable (8.29e-4)" "unprognostic (6.59e-2)" "unprognostic (1.25e-1)" "unprognostic (1.63e-1)" "unprognostic (1.46e-1)" 8.4 7.3 9.9 4.7 9.9 4.9 9.6 9.6 12.1 11.4 10.0 15.2 12.5 15.7 6.1 10.3 12.4 8.5 9.8 9.9 10.0 10.3 4.7 8.8 6.3 11.2 10.5 9.3 12.3 7.7 15.4 5.6 10.7 12.3 6.2 6.4 10.1 11.0 10.7 11.7 9.9 8.0 10.0 7.2 12.8 32.6 10.9 6.1 10.9 5.5 4.6 12.4 10.3 10.1 9.3 13.0 13.9 35.4 7.8 17.8 15.8 5.5 9.6 7.1 8.9 10.6 23.7 11.1 25.2 13.4 10.2 9.9 6.1 12.0 3.9 8.9 8.6 6.2 12.7 9.4 16.2 7.2 10.9 15.1 20.5 20.7 12.5 13.7 23.5 14.3 11.9 8.4 24.6 28.7 25.9 14.1 10.9 8.4 13.3 21.8 7.0 13.9 18.0 11.9 24.2 21.1 14.0 40.9 11.9 7.9 18.6 14.0 26.0 21.2 16.9 19.8 9.4 6.2 6.8 16.8 17.7 8.3 18.8 4.3 6.3 9.1 4.5 7.9 4.1 5.3 4.0 5.1 8.7 3.4 1.8 3.2 2.1 3.2 10.8 5.3 4.5 4.3 9.9 9.9 9.6 12.1 9.9 10.0 11.2 10.5 10.7 10.0 10.9 10.1 12.6 16.0 4.6 20.5 10.4 9.4 17.3 17.7 9.1 17.7 14.2 17.8 3.2 20.0 13.3 16.5 52.1 14.7 6.8 17.7 7.9 24.4 69.3 20.3 14.6 12.5 12.1 8.2 9.5 19.0 18.1 12.4 14.8 11.2 3.8 22.8 13.2 3.3 9.9 6.7 7.0 15.6 12.2 7.3 7.7 95.9 14.6 6.9 14.2 10.3 14.5 21.0 8.2 6.0 8.1 19.6 17.7 12.8 5.9 13.7 21.9 11.1 29.5 67.9 13.1 15.3 12.4 84.7 39.5 8.8 8.4 14.0 8.2 16.0 14.2 11.2 AP5Z1 "KIAA0415, SPG48, zeta" ENSG00000242802 "Adaptor related protein complex 5 subunit zeta 1" O43299 7 4775615-4794397 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Protein transport, Transport" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035693 Supported Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" Nucleoplasm "HPA035693: AB_10960687" "unprognostic (1.64e-1)" "unprognostic (5.22e-2)" "unprognostic (3.01e-3)" "unprognostic (4.24e-2)" "unprognostic (2.43e-3)" "unprognostic (5.19e-1)" "prognostic unfavorable (1.35e-5)" "unprognostic (1.50e-1)" "unprognostic (2.03e-1)" "unprognostic (1.04e-1)" "unprognostic (1.10e-3)" "unprognostic (1.26e-2)" "unprognostic (5.32e-3)" "unprognostic (8.28e-2)" "unprognostic (1.71e-1)" "unprognostic (1.95e-2)" "unprognostic (2.22e-1)" 14.8 18.5 7.0 0.7 7.1 1.5 11.8 7.3 10.0 12.4 5.8 13.2 1.1 13.4 1.0 11.0 11.0 0.8 7.7 6.9 5.7 9.2 9.2 12.9 1.8 8.3 6.5 11.8 9.9 0.7 9.8 1.1 7.4 11.7 0.4 0.6 12.4 0.7 8.5 21.8 15.5 0.4 5.9 22.9 12.0 8.6 7.4 0.9 11.2 0.2 0.6 13.4 10.9 7.3 2.8 4.2 0.7 2.4 1.0 0.9 4.3 1.3 1.9 2.0 1.7 5.2 3.5 1.6 1.8 0.9 5.1 5.4 0.7 0.5 0.6 1.8 3.5 2.4 4.5 4.6 3.0 2.5 5.1 2.2 1.6 1.8 1.3 0.7 0.5 2.2 3.4 1.1 1.2 7.7 0.3 15.0 5.9 0.3 4.3 2.9 2.6 4.8 1.0 4.4 1.7 3.0 1.8 8.7 6.4 0.5 6.4 8.9 3.8 2.3 4.4 6.5 1.7 8.5 7.4 2.3 1.7 5.6 3.6 1.9 2.3 2.9 2.4 2.8 1.4 1.9 1.8 2.4 1.2 1.8 2.5 2.2 2.2 2.4 2.5 2.4 1.8 1.3 7.0 7.1 7.3 10.0 6.9 5.7 8.3 6.5 7.4 5.9 7.4 7.3 12.4 9.6 15.0 7.5 18.2 6.9 2.9 8.8 8.0 10.5 5.7 5.8 4.3 15.7 6.6 11.0 4.2 11.5 20.3 20.1 0.0 14.1 2.2 9.9 10.1 11.6 12.0 5.0 12.4 13.6 7.7 9.9 21.4 16.4 17.1 14.3 12.5 8.1 28.7 18.5 10.7 15.1 10.2 12.3 10.7 1.5 13.4 16.3 14.2 13.1 23.4 8.2 21.6 10.6 12.6 20.6 15.9 10.9 19.8 4.9 14.7 6.8 8.3 9.4 0.0 5.8 9.5 8.1 10.8 7.6 11.1 16.6 15.6 12.6 14.1 3.8 APMAP "BSCv, C20orf3" ENSG00000101474 "Adipocyte plasma membrane associated protein" Q9HDC9 20 24962925-24992751 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 314.0" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 325.4;Hepatocytes: 251.1;Syncytiotrophoblasts: 751.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "granulocytes: 680.7;NK-cells: 343.8;T-cells: 367.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012863, HPA064700" Approved Approved "Plasma membrane" NA NA 130000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA012863: AB_1845683, HPA064700: AB_2685328" "unprognostic (4.07e-3)" "unprognostic (2.50e-2)" "unprognostic (1.20e-1)" "unprognostic (8.16e-2)" "unprognostic (6.79e-2)" "unprognostic (2.14e-2)" "unprognostic (1.10e-2)" "unprognostic (4.09e-2)" "unprognostic (3.10e-2)" "unprognostic (1.19e-2)" "unprognostic (6.46e-2)" "unprognostic (1.54e-1)" "unprognostic (7.99e-3)" "unprognostic (8.26e-2)" "unprognostic (1.67e-1)" "unprognostic (1.23e-1)" "unprognostic (3.51e-2)" 168.0 44.6 59.2 47.2 60.1 187.4 84.6 76.0 65.4 41.8 62.2 46.5 32.7 46.8 106.3 26.7 46.0 43.1 37.5 64.1 72.6 50.5 314.0 53.2 44.0 61.4 62.8 40.8 45.2 83.4 78.7 80.2 68.6 44.2 42.9 32.0 40.1 47.9 39.5 55.8 34.7 49.2 60.5 66.6 38.5 54.2 69.7 42.4 209.1 24.4 34.1 51.8 29.5 68.8 110.6 191.3 90.0 139.5 175.3 97.5 94.4 141.8 153.4 133.3 137.4 113.7 189.3 45.9 161.1 170.6 232.1 198.1 85.0 165.1 149.1 62.3 69.7 51.2 66.0 226.9 140.9 99.5 115.4 134.3 226.9 154.9 107.0 173.8 192.5 73.4 61.5 195.8 128.6 168.1 68.9 108.2 59.3 166.6 172.1 56.3 312.8 96.3 140.2 98.9 150.6 59.4 146.9 240.5 157.1 92.0 87.6 78.8 173.7 156.9 140.6 134.7 209.5 113.0 134.3 50.9 83.1 148.0 151.9 61.8 99.3 198.9 367.9 98.6 228.8 36.4 100.8 268.2 102.1 37.4 78.6 202.2 680.7 343.8 71.3 50.7 75.0 363.3 59.2 60.1 76.0 65.4 64.1 72.6 61.4 62.8 68.6 60.5 69.7 68.8 28.5 19.2 32.7 25.8 22.2 24.3 46.7 77.6 17.1 51.4 48.1 32.1 17.5 34.3 39.7 49.7 10.4 325.4 163.2 18.9 17.6 72.0 22.9 18.0 26.3 42.4 18.0 33.6 24.0 45.4 50.6 40.6 15.3 23.8 36.1 68.6 41.4 251.1 95.9 16.8 25.4 19.4 85.5 50.0 94.8 32.5 65.0 59.5 46.2 42.2 105.1 35.0 222.5 19.6 15.9 40.8 25.4 82.0 54.9 34.1 20.8 13.2 24.5 22.5 39.5 36.9 33.2 97.1 90.1 16.7 20.0 751.1 96.7 38.3 28.0 28.1 APOBEC3D "APOBEC3DE, APOBEC3E, ARP6" ENSG00000243811 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3D" Q96AK3 22 39021113-39033277 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.3" "Cell type enhanced" "Detected in many" "B-cells: 6.7;NK-cells: 9.2;Plasma cells: 6.4;T-cells: 8.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 11.8;Karpas-707: 46.7" HPA055116 Approved NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA055116: AB_2682701" "prognostic favorable (2.51e-5)" "prognostic favorable (1.31e-4)" "unprognostic (2.69e-2)" "prognostic favorable (4.47e-4)" "unprognostic (2.62e-2)" "unprognostic (3.06e-2)" "unprognostic (2.46e-1)" "unprognostic (1.18e-1)" "unprognostic (4.52e-2)" "unprognostic (2.45e-2)" "unprognostic (4.50e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (3.76e-7)" "unprognostic (4.76e-2)" "unprognostic (6.00e-2)" "unprognostic (1.06e-2)" "prognostic favorable (3.01e-4)" 1.7 2.2 1.2 8.6 1.2 2.5 1.8 1.5 1.2 3.5 1.1 3.5 3.8 3.3 3.0 1.7 5.2 4.1 1.2 1.0 0.9 1.6 1.2 3.3 15.3 1.6 1.2 4.1 0.5 1.1 0.9 2.2 1.3 2.6 4.3 0.3 2.8 2.3 0.9 1.4 5.3 2.4 1.3 12.0 5.3 2.4 1.1 7.7 1.9 1.2 13.8 4.6 2.7 1.4 0.5 0.0 0.3 2.1 3.1 5.5 1.9 0.3 3.3 3.9 4.4 0.9 5.3 6.1 0.9 4.4 2.5 0.6 0.3 0.0 1.4 11.1 1.2 10.7 0.1 0.0 8.3 1.5 11.8 3.6 0.5 6.3 0.0 0.0 2.9 9.0 2.7 46.7 0.2 0.0 5.2 3.4 0.8 0.0 0.5 4.3 0.3 0.1 0.0 0.0 0.1 0.3 0.2 0.1 1.7 1.4 0.1 0.5 1.1 0.1 1.2 0.6 0.0 3.2 3.9 0.8 1.6 3.3 1.5 4.8 1.3 3.5 8.0 3.5 5.2 6.7 5.8 7.3 0.8 6.8 2.7 3.6 1.7 4.9 6.5 5.4 5.8 3.4 1.2 1.2 1.5 1.2 1.0 0.9 1.6 1.2 1.3 1.3 1.1 1.4 0.9 3.2 0.5 0.0 6.7 1.0 1.5 0.9 0.0 0.2 0.3 0.6 0.4 5.7 1.1 1.8 0.0 1.3 3.8 3.0 0.0 0.2 0.5 1.0 0.8 1.9 1.8 1.7 0.0 0.2 0.7 1.8 2.6 0.6 0.0 1.1 2.5 0.2 2.5 0.0 0.0 3.6 0.0 3.4 1.0 0.0 3.1 1.1 3.6 2.8 1.2 0.3 9.2 0.5 0.0 0.2 0.1 1.9 6.4 1.4 1.3 0.3 2.7 0.5 0.0 0.9 1.4 0.2 0.4 0.2 0.9 0.5 8.7 0.8 2.1 2.6 APOOL "AAIR8193, CXorf33, FAM121A, Mic27, MICOS27, UNQ8193" ENSG00000155008 "Apolipoprotein O like" Q6UXV4 X 85003877-85093316 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000612 Approved Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA000612: AB_1078594" "prognostic unfavorable (2.68e-5)" "unprognostic (2.72e-2)" "unprognostic (6.16e-2)" "unprognostic (5.71e-3)" "unprognostic (4.27e-3)" "unprognostic (1.47e-1)" "unprognostic (2.73e-1)" "unprognostic (2.22e-2)" "unprognostic (8.35e-2)" "unprognostic (1.10e-1)" "unprognostic (2.77e-1)" "unprognostic (8.20e-2)" "prognostic favorable (1.35e-12)" "unprognostic (2.67e-2)" "unprognostic (5.65e-2)" "unprognostic (7.11e-2)" "unprognostic (7.51e-2)" 5.9 6.5 2.8 3.7 3.2 3.7 6.6 3.6 5.2 4.3 5.4 5.9 5.9 4.4 4.7 6.2 5.1 4.0 11.5 4.2 3.9 11.2 14.5 4.3 3.3 4.5 4.3 4.1 6.0 11.6 3.2 4.1 4.6 5.9 6.5 6.8 5.8 4.4 17.8 6.7 4.6 5.9 2.9 3.5 6.8 2.2 4.6 3.6 8.3 17.9 3.5 4.2 4.0 4.3 11.4 6.5 6.0 8.2 16.9 11.7 6.4 7.4 6.9 6.2 6.0 7.0 6.3 8.3 6.9 8.4 11.7 8.8 18.3 7.0 9.3 8.4 8.0 8.8 10.2 7.2 11.0 17.5 9.1 11.8 11.8 10.4 18.4 7.2 8.8 10.7 15.2 10.7 10.8 6.1 7.2 7.1 4.9 6.8 12.1 7.9 14.6 8.6 7.8 8.3 0.6 9.8 14.1 12.7 8.8 6.4 7.7 8.3 9.2 8.5 8.3 17.5 8.6 6.9 24.4 7.1 10.9 12.4 7.3 2.4 2.0 0.6 1.9 2.8 1.7 2.1 1.7 1.4 2.1 1.9 2.1 2.0 0.4 1.2 2.5 2.6 1.0 1.0 2.8 3.2 3.6 5.2 4.2 3.9 4.5 4.3 4.6 2.9 4.6 4.3 16.7 16.0 19.1 25.8 10.7 5.6 13.3 5.3 6.2 26.7 16.8 11.9 45.4 15.7 7.7 20.2 14.6 15.3 9.3 10.6 13.7 18.1 0.2 17.0 15.4 13.0 37.1 14.9 32.3 14.0 11.3 13.9 17.3 17.4 21.5 18.3 15.0 51.6 12.0 21.9 26.2 15.3 4.1 15.2 2.3 0.8 13.7 11.4 0.0 21.5 9.5 13.6 8.2 30.2 36.2 17.5 14.6 15.4 8.7 19.6 15.6 43.7 7.6 16.8 19.7 19.3 16.9 3.1 8.2 11.5 3.4 19.4 6.6 16.8 15.4 17.8 AQP6 AQP2L ENSG00000086159 "Aquaporin 6" Q13520 12 49967194-49977139 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "kidney: 52.7" "Cell type enhanced" "Detected in some" "Astrocytes: 4.2;Cardiomyocytes: 8.3;Collecting duct cells: 5.5;Ionocytes: 2.0" "Cancer enriched" "Detected in many" 9 "renal cancer: 9.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "OE19: 1.4" "Region enriched" "Detected in some" 7 "cerebellum: 21.0" "Not detected" "Not detected" HPA015278 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA015278: AB_10600982" "unprognostic (1.23e-1)" "unprognostic (1.32e-2)" "unprognostic (9.53e-2)" "unprognostic (2.02e-2)" "unprognostic (6.46e-2)" "unprognostic (4.60e-3)" "unprognostic (3.45e-2)" "unprognostic (1.46e-2)" "unprognostic (1.36e-1)" "unprognostic (8.68e-3)" "unprognostic (1.71e-1)" "unprognostic (2.00e-1)" "unprognostic (1.74e-1)" "unprognostic (6.85e-2)" "unprognostic (9.22e-2)" "unprognostic (9.03e-2)" "unprognostic (1.77e-1)" 0.1 0.2 2.8 0.1 4.1 0.0 0.1 5.6 2.6 0.3 1.6 0.6 0.1 0.1 0.2 0.1 0.1 0.1 0.2 2.7 2.5 52.7 0.3 0.1 0.0 4.9 4.6 0.0 0.1 0.2 0.2 0.0 5.2 0.2 0.0 0.2 1.0 0.2 0.0 0.3 0.2 0.1 3.4 0.0 0.4 2.4 6.1 0.0 0.0 0.0 0.0 0.1 0.1 3.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 1.4 0.1 0.2 0.0 0.1 0.2 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4.1 5.6 2.6 2.7 2.5 4.9 4.6 5.2 3.4 6.1 3.3 0.0 0.0 0.0 4.2 0.1 0.0 0.0 0.6 0.0 0.1 0.4 0.3 8.3 0.0 0.9 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 2.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.5 1.6 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.2 0.6 0.0 0.0 0.1 0.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 AQP9 "HsT17287, SSC1" ENSG00000103569 "Aquaporin 9" O43315 15 58138169-58185911 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "liver: 702.7" "Group enriched" "Detected in some" 4 "Hepatocytes: 313.9;Macrophages: 82.1" "Cancer enriched" "Detected in many" 30 "liver cancer: 132.4" "Region enhanced" "Detected in many" "cerebral cortex: 14.4" "Immune cell enriched" "Detected in many" 20 "neutrophil: 1161.4" "Lineage enriched" "Detected in many" 20 "granulocytes: 1161.4" "Cell line enriched" "Detected in some" 29 "U-87 MG: 29.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA074762, CAB075684" Enhanced NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" "CAB075684: , HPA074762: AB_2732267" "unprognostic (1.91e-1)" "unprognostic (1.92e-1)" "unprognostic (7.30e-2)" "unprognostic (2.67e-1)" "unprognostic (1.24e-2)" "unprognostic (4.15e-2)" "unprognostic (1.36e-3)" "unprognostic (2.28e-2)" "unprognostic (3.82e-2)" "unprognostic (2.03e-1)" "unprognostic (4.80e-3)" "unprognostic (6.98e-2)" "prognostic unfavorable (5.72e-11)" "unprognostic (8.78e-2)" "unprognostic (1.13e-2)" "unprognostic (1.25e-1)" "unprognostic (8.39e-2)" 18.2 0.8 0.8 72.9 0.9 67.5 2.4 0.9 14.4 1.3 0.8 0.9 0.2 1.2 43.4 1.2 7.1 5.3 1.7 3.2 0.5 0.9 702.7 22.2 0.6 0.7 1.0 0.5 1.6 5.6 0.3 6.2 4.0 0.9 0.3 0.4 1.1 0.7 0.5 22.0 0.9 6.4 0.6 42.7 1.5 0.3 6.9 1.8 0.6 7.5 0.8 32.6 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 29.7 0.1 0.0 0.2 58.4 1.2 0.1 17.5 0.1 0.5 0.1 0.0 1.8 0.1 0.1 0.0 1161.4 0.3 23.0 0.6 0.3 18.9 0.8 0.9 0.9 14.4 3.2 0.5 0.7 1.0 4.0 0.6 6.9 0.8 0.7 0.0 12.2 0.3 2.3 0.4 0.2 0.0 0.0 0.0 0.1 0.0 1.1 5.7 3.1 0.0 0.0 0.3 0.5 0.0 0.0 0.1 2.1 0.3 0.1 0.7 0.0 13.9 2.4 0.2 0.9 1.9 0.0 1.8 7.6 0.0 7.9 313.9 40.8 0.0 0.8 0.0 0.0 28.5 6.2 1.9 0.3 82.1 0.0 0.0 18.9 0.0 1.0 0.5 0.2 0.5 0.0 0.0 0.7 0.2 0.0 0.3 1.5 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.6 0.8 1.5 0.0 0.0 0.1 ARAF ARAF1 ENSG00000078061 "A-Raf proto-oncogene, serine/threonine kinase" P10398 X 47561205-47571908 "Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066326 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA066326: AB_2685659" "unprognostic (1.21e-1)" "unprognostic (5.69e-3)" "unprognostic (2.47e-2)" "unprognostic (2.10e-2)" "unprognostic (7.63e-2)" "unprognostic (9.35e-2)" "unprognostic (1.79e-2)" "unprognostic (1.07e-1)" "unprognostic (3.76e-2)" "unprognostic (1.61e-1)" "unprognostic (6.75e-2)" "unprognostic (8.65e-2)" "prognostic favorable (1.45e-6)" "unprognostic (1.97e-1)" "unprognostic (2.01e-1)" "unprognostic (6.37e-2)" "unprognostic (4.71e-2)" 37.7 41.7 17.8 36.9 20.8 102.3 36.2 19.2 21.1 34.8 22.6 40.9 37.8 36.6 21.2 32.2 35.0 32.5 50.8 17.1 18.0 44.6 55.7 39.4 40.4 22.8 20.5 39.5 59.1 51.8 27.7 31.3 20.1 40.9 33.3 15.4 45.1 34.6 136.3 36.0 39.7 31.3 18.8 46.1 46.7 12.0 21.0 38.0 39.4 85.6 31.5 36.1 30.8 20.4 49.1 69.5 29.2 46.9 43.5 34.2 39.0 40.3 42.3 58.6 54.1 57.2 58.6 29.0 32.4 54.6 49.2 67.3 51.8 56.3 34.3 53.5 61.9 29.4 74.4 30.6 61.4 58.3 85.1 45.0 56.0 56.2 49.6 39.2 45.9 36.0 55.2 55.7 40.5 83.3 42.6 64.0 41.8 41.2 77.8 39.2 38.0 65.5 34.4 46.7 32.8 25.0 43.7 39.7 24.5 47.0 74.9 43.3 44.2 38.0 42.5 76.2 41.4 71.1 49.2 22.5 50.8 65.3 31.1 48.3 47.8 61.3 44.1 57.8 40.3 32.6 38.4 40.9 55.2 37.3 33.5 40.5 37.8 38.7 67.9 40.4 41.6 50.8 17.8 20.8 19.2 21.1 17.1 18.0 22.8 20.5 20.1 18.8 21.0 20.4 13.3 16.0 29.2 7.5 25.8 15.7 25.0 29.0 18.2 5.3 15.0 9.8 25.1 34.3 22.0 18.4 10.4 33.0 26.3 43.8 23.5 29.3 1.3 11.4 10.8 17.5 31.8 22.3 5.0 34.3 30.4 16.9 39.3 15.6 16.5 13.6 24.3 42.6 28.0 13.5 5.5 35.9 40.7 26.4 21.6 4.3 17.4 25.8 33.8 4.7 43.7 18.4 32.0 8.5 8.9 26.2 41.5 17.7 27.9 20.3 44.6 27.1 11.5 9.0 19.7 15.9 18.0 8.2 10.5 17.7 16.2 44.6 26.5 12.5 32.3 24.6 ARFGEF3 "BIG3, C6orf92, dJ171N11.1, KIAA1244, PPP1R33" ENSG00000112379 "ARFGEF family member 3" Q5TH69 6 138161939-138344663 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.4;salivary gland: 18.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 114.6;Excitatory neurons: 200.9;Inhibitory neurons: 207.8;Oligodendrocyte precursor cells: 173.9;Oligodendrocytes: 378.1" "Cancer enhanced" "Detected in all" "prostate cancer: 24.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 14.8;RH-30: 13.4;RT4: 19.4;SK-BR-3: 22.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036350 Uncertain NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA036350: AB_10672084" "prognostic unfavorable (8.20e-4)" "unprognostic (4.31e-2)" "unprognostic (9.91e-3)" "unprognostic (5.91e-2)" "unprognostic (2.20e-2)" "unprognostic (4.53e-2)" "unprognostic (4.30e-3)" "unprognostic (1.21e-2)" "unprognostic (7.41e-2)" "unprognostic (7.82e-2)" "unprognostic (3.46e-2)" "unprognostic (4.93e-2)" "unprognostic (1.31e-2)" "unprognostic (1.35e-1)" "unprognostic (2.38e-1)" "unprognostic (8.87e-2)" "unprognostic (1.69e-2)" 1.2 3.8 13.4 0.7 16.4 0.4 7.9 20.1 17.7 5.0 0.0 4.2 2.2 0.7 0.9 0.4 2.2 1.7 1.0 16.7 13.0 2.1 0.1 6.4 0.2 11.1 17.7 0.1 8.7 15.8 7.0 1.4 14.4 12.0 4.8 2.8 18.0 1.0 0.2 1.2 1.9 0.7 7.5 0.4 10.0 0.6 15.2 0.1 1.9 0.7 0.2 3.4 0.4 28.4 8.0 3.1 0.0 0.6 0.0 0.0 4.7 0.3 0.2 0.2 0.0 0.1 0.4 0.0 3.1 0.3 2.7 2.6 3.8 2.0 0.0 0.0 4.9 0.0 1.5 0.9 0.0 3.0 0.0 0.0 0.9 0.0 0.9 3.5 4.1 2.7 0.0 4.9 0.0 14.8 0.0 0.0 2.7 8.5 3.4 0.6 13.4 2.6 2.6 19.4 6.9 0.0 7.8 22.2 0.9 0.3 4.4 0.0 0.4 0.2 2.2 0.0 7.9 1.7 6.7 0.0 3.2 1.8 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 16.4 20.1 17.7 16.7 13.0 11.1 17.7 14.4 7.5 15.2 28.4 9.4 16.0 114.6 34.3 0.5 0.0 18.8 0.0 6.2 19.0 39.9 12.6 6.4 14.3 44.6 3.7 0.0 16.5 0.8 2.5 3.9 11.4 83.0 8.6 1.4 11.9 66.7 2.7 200.9 24.7 2.4 4.1 41.3 17.7 2.5 0.1 8.2 0.3 1.4 11.8 207.8 44.2 0.0 0.0 0.0 22.0 0.0 0.5 0.0 36.5 2.0 0.9 0.0 173.9 378.1 14.2 8.4 0.0 0.9 67.6 2.5 0.3 37.2 3.3 0.0 3.5 0.9 4.1 1.1 3.0 0.0 6.2 0.8 0.1 13.2 42.7 ARHGAP22 RhoGAP2 ENSG00000128805 "Rho GTPase activating protein 22" Q7Z5H3 10 48446036-48656265 "Predicted intracellular proteins" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Developmental protein, GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.6" "Cell type enhanced" "Detected in many" "Late spermatids: 122.7;Microglial cells: 227.7;Oligodendrocyte precursor cells: 141.8;Oligodendrocytes: 200.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 68.8;LHCN-M2: 64.8;TIME: 66.2;U-87 MG: 82.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020696, HPA040391, HPA064439" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB020696: , HPA040391: AB_2676957, HPA064439: AB_2685266" "unprognostic (1.87e-1)" "unprognostic (3.98e-2)" "unprognostic (2.38e-2)" "unprognostic (2.62e-1)" "unprognostic (1.07e-1)" "unprognostic (6.74e-3)" "unprognostic (4.81e-3)" "unprognostic (2.78e-1)" "unprognostic (1.66e-1)" "unprognostic (3.03e-1)" "unprognostic (1.12e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (2.16e-8)" "unprognostic (7.40e-2)" "unprognostic (1.60e-1)" "unprognostic (9.39e-2)" "unprognostic (3.66e-2)" 2.6 1.9 12.0 3.0 15.7 1.4 1.6 17.6 14.5 1.6 7.7 2.0 0.6 1.1 0.7 1.4 1.8 1.8 4.4 11.9 12.7 1.3 0.8 2.0 2.7 22.6 17.0 4.8 1.7 0.9 2.0 0.8 20.1 3.3 1.0 0.4 2.0 1.1 1.9 2.2 1.6 1.4 16.9 2.8 1.2 4.8 17.0 2.8 6.6 1.6 2.2 2.1 2.2 22.2 6.2 1.4 0.4 0.0 5.1 20.8 4.3 31.9 15.1 3.0 4.1 7.0 0.9 0.0 1.2 13.1 2.1 12.4 0.4 11.2 5.4 0.6 11.5 18.2 0.2 0.1 2.7 2.0 2.0 5.0 11.2 37.1 3.0 68.8 20.6 0.0 17.4 3.0 64.8 0.2 0.2 0.1 7.2 0.0 0.5 0.1 0.0 7.9 6.5 0.7 1.1 6.4 1.5 0.1 0.6 0.6 0.4 0.3 66.2 30.1 0.4 3.8 23.8 0.0 0.0 0.0 82.5 0.3 4.9 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 12.0 15.7 17.6 14.5 11.9 12.7 22.6 17.0 20.1 16.9 17.0 22.2 0.9 0.0 1.7 4.2 2.9 3.4 4.1 6.8 4.6 1.1 0.8 3.0 2.9 1.5 2.9 0.0 2.1 11.6 3.2 0.2 0.0 2.8 53.6 0.7 1.6 2.4 0.0 10.9 51.7 4.4 0.7 6.5 0.5 1.0 0.0 4.4 1.8 0.0 10.3 0.0 29.8 0.3 2.0 7.6 14.2 122.7 2.8 15.6 1.8 227.7 14.8 1.8 0.0 141.8 200.8 2.5 0.0 6.0 0.5 1.9 0.0 0.2 3.8 1.4 0.0 1.6 4.2 1.6 4.3 0.4 0.6 1.0 0.7 10.6 0.1 0.6 ARHGAP28 "FLJ10312, KIAA1314" ENSG00000088756 "Rho GTPase activating protein 28" Q9P2N2 18 6729716-6915716 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "placenta: 25.9;testis: 77.5" "Group enriched" "Detected in many" 14 "Early spermatids: 536.8;Late spermatids: 488.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 4 "neutrophil: 3.0" "Lineage enriched" "Detected in single" 11 "granulocytes: 3.0" "Cell line enhanced" "Detected in many" "AF22: 30.4;CACO-2: 32.8;SuSa: 22.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA030413, HPA030414, HPA030415" Enhanced Supported "Cell Junctions" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 83: Testis - Spermatogenesis" "Cluster 12: NES - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Cell Junctions" "HPA030413: AB_10601455, HPA030414: AB_10670042, HPA030415: AB_10669598" "unprognostic (8.33e-2)" "unprognostic (8.79e-3)" "unprognostic (3.15e-3)" "unprognostic (6.94e-5)" "unprognostic (1.49e-1)" "unprognostic (2.92e-2)" "unprognostic (1.11e-3)" "unprognostic (1.10e-1)" "unprognostic (7.56e-3)" "unprognostic (9.52e-4)" "unprognostic (1.43e-2)" "unprognostic (3.12e-1)" "unprognostic (4.53e-3)" "unprognostic (3.59e-3)" "unprognostic (6.00e-2)" "unprognostic (3.61e-2)" "unprognostic (2.76e-2)" 4.7 1.9 1.1 1.7 1.2 0.8 2.7 1.7 1.6 8.6 0.8 1.9 1.7 2.9 8.7 1.9 3.1 6.6 2.0 1.5 1.6 8.4 0.9 4.6 1.7 0.4 0.2 10.4 3.8 3.0 0.8 25.9 0.5 3.9 2.3 1.4 0.8 2.2 4.9 2.1 1.8 1.4 0.1 12.6 2.1 77.5 1.1 3.8 2.9 1.6 0.9 5.4 3.0 0.8 0.2 0.2 30.4 3.1 6.3 10.5 4.9 2.2 5.1 2.5 5.3 32.8 0.2 0.2 1.0 0.4 1.7 1.4 0.1 0.8 3.7 1.0 1.8 0.1 2.9 0.2 1.1 0.1 0.1 12.6 0.6 2.7 0.2 0.3 7.8 0.5 0.8 2.5 4.1 0.5 0.5 0.3 9.6 0.4 1.4 0.1 2.7 0.2 0.0 2.9 2.9 11.9 0.1 2.8 0.5 22.6 0.2 0.1 1.3 0.5 13.1 10.1 0.4 0.2 0.1 0.1 5.0 0.3 1.1 0.7 0.2 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.1 3.0 0.1 0.0 0.2 0.0 0.0 1.1 1.2 1.7 1.6 1.5 1.6 0.4 0.2 0.5 0.1 1.1 0.8 8.3 0.0 1.9 6.2 0.1 1.9 1.3 0.2 0.0 1.5 0.9 0.5 1.8 0.0 0.7 1.8 20.9 14.9 0.0 0.0 0.0 1.1 536.8 0.5 14.6 7.9 0.0 0.0 7.1 2.7 2.7 16.1 0.0 0.4 0.0 25.8 4.2 0.2 2.1 0.0 34.4 0.1 0.0 0.3 0.4 488.0 18.3 0.5 0.0 12.2 0.0 0.2 0.0 24.6 3.6 0.7 0.0 14.3 0.1 4.7 0.0 3.8 0.0 0.8 0.0 11.0 5.4 14.3 3.7 0.8 1.4 6.6 0.3 23.7 0.0 1.3 ARHGAP30 FLJ00267 ENSG00000186517 "Rho GTPase activating protein 30" Q7Z6I6 1 161046946-161069970 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 57.6;lymphoid tissue: 77.0" "Cell type enhanced" "Detected in many" "B-cells: 71.6;dendritic cells: 103.4;Kupffer cells: 77.8;Macrophages: 79.1;monocytes: 133.0;NK-cells: 268.8;T-cells: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 118.2;HL-60: 92.5;HMC-1: 123.4;Karpas-707: 93.1;MOLT-4: 75.8;THP-1: 90.9;U-266/70: 138.6;U-266/84: 97.7;U-698: 97.9;U-937: 72.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036300 Enhanced Supported Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA036300: AB_10601117" "unprognostic (7.31e-2)" "unprognostic (8.83e-3)" "unprognostic (7.46e-3)" "unprognostic (1.77e-3)" "unprognostic (7.41e-2)" "unprognostic (1.68e-3)" "unprognostic (3.05e-1)" "unprognostic (6.78e-3)" "unprognostic (1.94e-2)" "unprognostic (3.89e-2)" "unprognostic (7.91e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (9.78e-4)" "unprognostic (1.18e-1)" "unprognostic (1.08e-2)" "unprognostic (6.64e-2)" "unprognostic (2.65e-2)" 12.1 4.9 3.1 55.9 3.6 57.6 5.3 3.7 4.3 3.4 3.3 8.1 9.5 2.9 2.8 14.1 4.5 10.2 2.8 2.9 3.6 3.4 6.6 25.2 77.0 6.1 4.5 2.0 2.4 1.4 1.8 7.0 5.4 3.4 8.4 0.6 6.4 2.3 2.6 19.8 23.9 8.0 5.0 75.5 11.6 2.3 6.3 63.7 2.9 2.7 61.2 13.8 6.5 6.8 0.8 0.1 0.2 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.3 1.2 118.2 0.6 0.0 0.1 2.3 0.0 0.0 0.2 55.3 0.2 39.7 0.2 0.0 0.0 92.5 123.4 0.0 1.2 0.1 0.0 0.1 0.0 56.8 0.3 93.1 0.0 1.0 75.8 21.3 0.1 0.7 0.1 46.8 0.6 1.6 0.0 1.0 0.7 0.3 0.2 0.7 0.2 0.7 0.8 90.9 0.9 0.1 0.7 0.2 0.5 138.6 97.7 97.9 0.4 72.3 0.1 7.1 29.6 33.1 32.9 32.2 25.1 11.9 21.9 27.1 21.8 12.6 17.9 25.0 48.5 19.3 46.4 15.0 23.8 33.5 3.1 3.6 3.7 4.3 2.9 3.6 6.1 4.5 5.4 5.0 6.3 6.8 1.5 3.2 20.5 0.3 71.6 5.6 3.3 6.8 0.0 0.5 5.2 2.9 1.3 2.8 13.8 0.0 4.2 0.6 103.4 0.5 0.0 3.4 2.2 6.6 1.2 2.3 0.0 14.5 0.3 6.0 1.9 1.9 3.1 13.7 68.3 0.0 6.1 1.7 55.5 0.0 0.3 0.4 8.2 77.8 44.6 0.7 0.3 79.1 5.4 14.0 133.0 0.1 268.8 0.5 1.2 12.5 0.2 0.0 49.8 5.4 0.0 0.5 15.3 3.0 0.0 1.0 1.9 0.1 0.1 9.9 24.6 4.5 105.1 0.2 0.5 16.7 ARHGAP45 "HA-1, HMHA1, KIAA0223" ENSG00000180448 "Rho GTPase activating protein 45" Q92619 19 1065923-1086628 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 68.3;intestine: 53.2;lung: 39.5;lymphoid tissue: 106.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 48.1;Cytotrophoblasts: 40.1;dendritic cells: 62.7;Extravillous trophoblasts: 56.6;Hofbauer cells: 40.0;monocytes: 72.4;Syncytiotrophoblasts: 75.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 73.7;Karpas-707: 100.4;RPMI-8226: 74.7;THP-1: 92.3;U-266/70: 130.8;U-937: 72.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA019816, HPA079252" Enhanced Supported "Plasma membrane,Cytosol" NA NA 1200000 "Cluster 32: T-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA019816: AB_1853923, HPA079252: " "unprognostic (1.34e-1)" "unprognostic (5.13e-3)" "unprognostic (5.17e-3)" "prognostic favorable (6.02e-4)" "unprognostic (2.26e-1)" "prognostic favorable (7.82e-4)" "unprognostic (1.59e-2)" "unprognostic (2.17e-2)" "unprognostic (3.55e-1)" "unprognostic (4.78e-2)" "unprognostic (2.43e-1)" "unprognostic (2.05e-2)" "unprognostic (1.00e-1)" "unprognostic (4.59e-1)" "unprognostic (5.19e-2)" "unprognostic (3.24e-2)" "unprognostic (5.33e-2)" 11.2 5.5 3.6 43.1 3.4 68.3 5.5 4.4 7.5 4.2 5.1 12.4 7.2 3.5 0.5 5.5 6.7 5.0 4.4 3.3 4.4 7.8 7.4 39.5 58.4 9.1 5.4 2.0 2.7 0.8 4.5 6.0 6.9 5.9 2.6 8.7 6.4 1.5 2.1 3.9 53.2 2.2 7.6 106.1 10.9 3.5 8.1 32.9 9.0 0.8 18.6 6.6 5.5 11.4 11.2 2.1 0.1 12.1 0.0 0.0 27.8 0.1 0.0 0.0 0.0 29.2 13.9 73.7 3.0 0.0 0.4 9.6 2.1 0.6 0.0 54.7 1.0 10.1 22.6 3.5 0.4 48.6 56.2 0.0 2.9 0.1 0.0 0.0 0.1 46.8 6.8 100.4 0.0 0.6 54.5 43.4 7.6 1.9 5.4 52.0 0.3 74.7 0.0 0.2 0.6 0.2 16.8 0.0 4.5 0.7 3.5 92.3 4.8 0.2 1.9 0.2 0.3 130.8 60.2 58.8 0.3 72.1 5.4 6.7 24.4 25.3 45.7 21.2 38.8 15.9 52.2 54.1 22.5 18.3 68.9 53.6 37.0 28.0 20.9 13.3 43.5 59.8 3.6 3.4 4.4 7.5 3.3 4.4 9.1 5.4 6.9 7.6 8.1 11.4 2.0 48.1 8.4 0.0 17.8 0.0 0.0 0.0 0.0 0.0 15.2 11.0 0.0 0.0 1.8 11.0 0.0 40.1 62.7 0.0 0.0 2.6 0.0 4.5 0.7 1.6 0.0 0.0 0.0 3.8 56.6 1.3 0.0 3.5 3.8 0.2 0.0 0.0 40.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.0 0.0 0.0 72.4 0.0 0.0 0.0 0.0 7.8 0.0 0.0 15.2 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 75.5 30.2 0.1 0.0 0.0 ARHGAP6 rhoGAPX-1 ENSG00000047648 "Rho GTPase activating protein 6" O43182 X 11117651-11665920 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 44.3;Microglial cells: 127.4;Oligodendrocyte precursor cells: 60.3;Prostatic glandular cells: 54.4;Sertoli cells: 46.0;Skeletal myocytes: 62.3;Smooth muscle cells: 44.4" "Cancer enhanced" "Detected in many" "prostate cancer: 12.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 26.2;ASC TERT1: 34.2;HEL: 36.4;HMC-1: 24.7;HSkMC: 33.8;K-562: 26.5;RT4: 20.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001798, HPA036779, HPA064390" Enhanced Supported Cytosol "Intracellular and membrane" NA NA 350000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA001798: , HPA036779: AB_10672229, HPA064390: AB_2685253" "unprognostic (2.36e-1)" "unprognostic (1.68e-2)" "unprognostic (3.49e-2)" "unprognostic (7.31e-2)" "unprognostic (6.34e-2)" "unprognostic (1.69e-2)" "unprognostic (4.70e-2)" "unprognostic (2.79e-1)" "unprognostic (1.70e-1)" "unprognostic (7.46e-4)" "unprognostic (1.53e-1)" "unprognostic (1.59e-1)" "prognostic favorable (1.55e-8)" "unprognostic (1.60e-2)" "unprognostic (5.96e-2)" "unprognostic (1.28e-2)" "unprognostic (7.99e-4)" 10.8 1.1 9.0 1.7 5.1 0.7 5.6 2.0 4.2 7.6 3.2 13.9 2.1 10.5 8.2 3.8 8.4 4.2 4.0 5.0 5.8 6.5 0.9 9.6 1.2 3.2 4.0 16.4 1.9 1.2 3.2 7.0 3.2 27.6 3.9 1.0 2.6 30.9 9.6 2.5 4.7 12.9 2.6 5.9 4.1 1.9 6.1 1.0 25.4 8.1 0.8 10.4 5.7 3.8 0.0 0.0 2.4 0.0 26.2 34.2 0.6 0.4 0.6 1.4 0.9 0.4 0.0 0.0 0.0 5.0 0.0 0.1 0.9 0.0 1.2 0.6 0.5 36.4 0.4 0.0 9.7 0.1 24.7 33.8 0.0 2.5 0.1 3.1 0.7 0.1 26.5 12.3 1.5 0.0 0.0 0.2 0.7 0.2 0.4 0.1 11.6 15.7 8.3 20.3 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.4 0.3 1.6 0.7 7.1 0.2 0.7 0.0 0.0 0.5 0.2 4.0 0.2 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.5 9.0 5.1 2.0 4.2 5.0 5.8 3.2 4.0 3.2 2.6 6.1 3.8 9.6 0.0 1.7 10.4 5.3 2.0 16.9 0.3 2.8 4.3 2.3 3.3 4.7 0.0 2.6 33.1 0.0 0.6 0.4 0.0 25.4 0.0 0.1 0.1 5.1 9.2 1.2 2.1 5.5 1.1 0.7 29.1 3.6 0.2 40.0 3.0 8.2 0.0 4.9 0.0 44.3 0.4 0.0 2.2 18.9 0.9 16.1 29.1 5.4 127.4 3.4 7.2 0.0 60.3 3.5 0.7 0.0 10.1 4.9 54.4 0.0 7.4 5.6 0.7 46.0 62.3 44.4 0.2 0.4 4.5 1.7 0.0 1.2 2.1 0.0 22.3 ARHGEF12 "KIAA0382, LARG" ENSG00000196914 "Rho guanine nucleotide exchange factor 12" Q9NZN5 11 120336413-120489937 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 274.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018911, CAB025581" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" Nucleoplasm "CAB025581: , HPA018911: AB_1845003" "unprognostic (1.55e-1)" "unprognostic (1.29e-1)" "unprognostic (6.91e-3)" "unprognostic (1.28e-1)" "unprognostic (7.28e-2)" "unprognostic (5.39e-2)" "unprognostic (1.56e-1)" "unprognostic (5.55e-2)" "unprognostic (4.79e-2)" "unprognostic (7.77e-2)" "unprognostic (4.34e-3)" "unprognostic (4.78e-2)" "prognostic favorable (5.43e-6)" "unprognostic (1.29e-1)" "unprognostic (4.38e-2)" "unprognostic (2.13e-1)" "unprognostic (1.48e-1)" 25.6 30.6 27.2 14.3 26.9 11.4 31.9 26.8 32.1 32.9 26.4 27.6 25.0 27.8 25.4 27.6 29.3 28.4 40.3 30.9 23.0 67.4 66.4 36.7 11.9 17.8 25.6 25.2 26.1 68.4 14.6 42.9 17.3 26.5 29.1 47.7 25.0 30.9 32.2 49.5 25.5 30.3 20.1 21.5 32.2 9.7 35.9 13.5 51.5 31.8 18.7 28.7 22.0 19.3 38.1 31.6 41.9 39.8 55.0 54.5 16.7 43.8 49.8 26.1 33.1 37.5 27.2 3.2 51.7 79.8 46.6 27.5 54.1 56.0 51.3 31.1 25.8 61.8 34.0 29.2 49.2 0.1 43.7 52.4 39.7 57.8 63.8 58.0 80.7 32.7 52.4 122.5 67.0 26.6 0.1 0.1 11.4 49.3 26.1 13.4 47.4 11.9 65.1 66.1 30.0 36.4 61.5 51.0 16.2 25.0 43.1 5.1 80.1 57.2 24.2 37.6 32.4 35.1 15.4 20.2 23.6 7.9 44.2 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 27.2 26.9 26.8 32.1 30.9 23.0 17.8 25.6 17.3 20.1 35.9 19.3 86.2 73.7 88.4 274.9 8.6 90.5 69.1 47.2 42.1 134.6 55.1 26.9 87.6 68.6 57.8 97.5 185.6 16.7 11.5 59.7 35.2 45.6 6.4 61.4 55.7 94.0 37.8 69.7 239.0 50.9 10.4 44.0 34.7 140.3 11.4 44.9 85.6 118.3 7.3 90.9 192.4 39.6 18.3 31.2 25.6 14.8 29.8 18.2 51.6 118.0 8.7 41.0 13.4 143.2 55.0 53.5 52.1 33.4 9.3 85.6 48.1 76.3 48.7 80.9 26.3 58.4 60.3 16.3 13.8 55.3 85.1 28.7 16.1 43.1 41.3 99.1 ARHGEF15 "ARGEF15, FLJ13791, KIAA0915, MGC44868, Vsm-RhoGEF" ENSG00000198844 "Rho guanine nucleotide exchange factor 15" O94989 17 8310241-8322514 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 47.7;breast: 41.6" "Group enriched" "Detected in some" 4 "Adipocytes: 66.4;Endothelial cells: 48.9;Hepatic stellate cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 48 "HUVEC TERT2: 40.4;TIME: 49.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA044443, HPA063495" Supported "Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA044443: AB_10960424, HPA063495: AB_2685023" "unprognostic (3.02e-1)" "unprognostic (2.97e-1)" "unprognostic (1.18e-2)" "unprognostic (7.09e-3)" "unprognostic (3.82e-1)" "unprognostic (7.29e-4)" "unprognostic (1.43e-2)" "unprognostic (1.84e-1)" "unprognostic (1.42e-1)" "unprognostic (3.40e-1)" "unprognostic (1.06e-2)" "unprognostic (1.45e-1)" "unprognostic (2.23e-3)" "unprognostic (4.88e-2)" "unprognostic (1.33e-1)" "unprognostic (1.89e-1)" "unprognostic (9.56e-3)" 47.7 5.9 4.6 4.1 4.2 0.0 41.6 4.1 4.7 8.7 3.0 6.9 3.1 10.9 1.6 4.8 9.8 7.3 35.5 4.1 4.1 15.8 2.9 22.1 3.1 4.7 4.5 3.8 4.2 3.4 4.0 14.7 4.8 8.0 2.0 0.2 5.1 3.5 13.2 7.7 6.5 7.2 4.0 7.9 6.9 2.2 5.2 1.6 12.4 10.9 1.8 12.3 8.3 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 49.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 4.2 4.1 4.7 4.1 4.1 4.7 4.5 4.8 4.0 5.2 3.6 66.4 0.0 3.0 0.3 0.5 2.8 0.3 0.0 0.6 0.8 0.5 0.4 8.9 2.8 0.0 1.8 0.0 0.0 0.2 0.1 0.0 0.0 3.3 0.4 0.2 48.9 0.0 0.0 0.2 0.0 0.1 1.0 0.0 1.3 0.0 0.0 37.1 0.0 0.1 0.0 0.5 0.0 0.0 1.4 2.8 4.4 0.0 0.5 7.2 11.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.4 0.0 0.0 0.0 0.1 0.0 1.6 1.5 0.4 0.2 0.2 1.0 0.1 0.3 0.7 0.0 0.3 ARHGEF2 "GEF-H1, GEFH1, KIAA0651, Lfc, LFP40, P40" ENSG00000116584 "Rho/Rac guanine nucleotide exchange factor 2" Q92974 1 155946851-156007070 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Immunity, Innate immunity, Mitosis, Neurogenesis" "Developmental protein, Guanine-nucleotide releasing factor" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 105.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043437 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 3: Monocytes - Immune response regulation" "HPA043437: AB_2678481" "unprognostic (2.27e-2)" "unprognostic (8.30e-3)" "unprognostic (3.24e-3)" "unprognostic (1.90e-3)" "unprognostic (4.14e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (9.20e-6)" "unprognostic (5.96e-2)" "unprognostic (2.14e-1)" "unprognostic (3.62e-2)" "unprognostic (2.59e-1)" "unprognostic (3.92e-1)" "prognostic unfavorable (7.17e-6)" "unprognostic (4.63e-2)" "unprognostic (2.70e-1)" "unprognostic (8.85e-3)" "unprognostic (7.98e-2)" 48.9 12.3 52.6 39.2 80.8 64.0 40.8 69.0 77.8 38.8 18.7 47.3 18.8 37.0 15.2 25.8 42.1 31.1 42.8 55.5 56.2 35.7 13.2 89.9 48.4 85.9 75.9 28.1 15.1 18.5 16.8 32.1 84.1 27.3 28.8 11.1 25.0 15.1 17.8 17.9 45.4 29.9 60.9 69.9 39.9 33.9 77.2 38.6 46.7 16.8 32.6 37.8 31.4 130.6 32.0 25.7 44.0 30.3 41.4 51.9 45.3 69.9 89.4 67.2 71.5 23.3 23.6 79.4 41.9 53.8 35.4 45.7 26.7 22.2 50.9 32.5 22.9 105.1 40.9 14.0 162.4 138.6 87.8 61.1 90.4 100.2 122.1 50.7 55.7 60.5 59.2 94.2 96.2 17.7 70.2 187.2 48.8 53.4 17.0 75.5 61.3 135.9 28.3 19.0 72.1 33.1 30.1 43.6 246.1 43.6 45.0 188.7 73.6 57.7 32.7 50.9 89.8 155.7 171.1 55.6 82.4 68.7 144.6 15.1 20.6 17.1 15.7 18.1 10.8 14.6 9.9 11.3 18.2 13.1 9.6 11.0 31.7 11.0 21.9 8.7 9.9 28.2 52.6 80.8 69.0 77.8 55.5 56.2 85.9 75.9 84.1 60.9 77.2 130.6 26.4 38.5 73.4 2.9 43.9 15.2 28.1 12.6 10.8 54.1 15.7 12.3 6.2 10.0 12.0 16.5 2.1 3.5 32.1 21.1 7.9 15.5 52.9 6.6 10.2 32.3 30.5 48.6 30.8 5.3 22.8 24.8 59.1 13.3 27.9 8.9 23.2 1.0 29.7 1.7 17.0 20.9 16.2 49.0 67.8 16.1 11.5 46.0 24.9 20.6 82.9 12.9 48.4 22.1 105.5 16.5 22.5 10.1 20.0 16.7 9.8 2.2 13.0 3.3 59.2 32.9 30.8 3.1 4.1 11.7 13.8 3.4 29.7 2.1 14.2 40.2 ARHGEF38 FLJ20184 ENSG00000236699 "Rho guanine nucleotide exchange factor 38" Q9NXL2 4 105552620-105708093 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 7.8;pancreas: 6.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 48.5;Breast glandular cells: 17.9;Respiratory ciliated cells: 31.9" "Cancer enhanced" "Detected in many" "prostate cancer: 5.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 2.8;RPTEC TERT1: 14.3;SK-BR-3: 8.0;T-47d: 8.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036510, HPA045484" Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm Centrosome "HPA036510: AB_10672357, HPA045484: AB_2679345" "unprognostic (1.49e-1)" "unprognostic (1.01e-1)" "unprognostic (1.62e-1)" "unprognostic (6.19e-3)" "unprognostic (2.09e-2)" "unprognostic (2.24e-3)" "unprognostic (1.85e-1)" "unprognostic (5.47e-3)" "unprognostic (2.79e-1)" "unprognostic (6.14e-5)" "unprognostic (1.17e-1)" "unprognostic (3.53e-3)" "unprognostic (3.16e-8)" "unprognostic (2.33e-3)" "unprognostic (6.16e-2)" "unprognostic (3.19e-3)" "unprognostic (6.45e-3)" 0.0 0.0 0.0 0.3 0.0 0.0 7.8 0.0 0.0 2.5 0.0 2.6 1.9 0.2 5.5 0.1 0.6 3.2 0.0 0.0 0.0 3.9 0.1 3.6 0.0 0.0 0.0 0.0 6.5 0.0 2.0 0.0 0.0 5.7 4.2 0.0 4.9 0.4 0.3 0.5 2.6 0.0 0.0 0.0 3.1 0.0 0.0 0.0 1.4 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 2.8 0.3 0.0 0.0 0.1 14.3 0.0 0.0 0.0 0.0 8.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.4 48.5 0.0 0.2 0.0 1.1 1.1 0.0 0.0 17.9 6.1 1.8 4.3 12.6 12.9 0.0 0.2 0.2 9.8 9.8 6.8 1.9 12.6 0.5 0.3 8.4 0.0 0.3 5.8 0.1 0.3 9.2 7.8 0.0 0.0 0.0 0.1 0.1 0.0 0.3 14.8 10.2 0.0 0.2 0.4 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.1 2.4 6.4 0.0 0.1 9.4 4.8 0.5 31.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 11.4 0.8 ARHGEF40 "FLJ10357, solo" ENSG00000165801 "Rho guanine nucleotide exchange factor 40" Q8TER5 14 21070273-21090248 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 6.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 6.2" "Cell line enhanced" "Detected in many" "ASC TERT1: 37.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030745, HPA030746, HPA030757" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA030745: , HPA030746: AB_10599613, HPA030757: AB_10600203" "unprognostic (6.30e-2)" "unprognostic (1.94e-1)" "unprognostic (2.36e-1)" "unprognostic (5.91e-2)" "unprognostic (2.55e-1)" "unprognostic (8.16e-3)" "unprognostic (1.27e-2)" "unprognostic (9.84e-3)" "unprognostic (1.33e-1)" "unprognostic (8.80e-2)" "unprognostic (1.64e-2)" "unprognostic (2.53e-1)" "unprognostic (6.01e-3)" "unprognostic (1.14e-2)" "unprognostic (1.38e-2)" "unprognostic (2.33e-1)" "unprognostic (8.95e-2)" 21.0 47.2 9.6 5.3 11.1 1.6 18.5 10.0 9.2 24.8 6.2 14.5 3.7 18.9 12.2 3.5 13.2 14.8 12.3 8.9 11.1 10.1 26.9 14.2 2.3 13.5 10.5 19.3 24.0 10.7 9.0 6.5 10.5 12.3 6.2 2.8 20.2 18.6 10.5 7.4 7.9 9.7 10.1 27.8 9.5 4.3 12.1 3.1 15.8 6.1 1.7 13.8 13.3 12.1 3.3 2.9 30.8 5.8 24.5 37.1 1.1 11.4 28.1 12.1 9.4 1.4 7.5 0.0 1.8 20.9 12.2 5.0 2.6 3.7 4.3 6.6 1.1 4.6 3.4 9.0 3.5 3.0 16.5 15.5 2.4 10.3 3.1 22.6 0.0 0.0 1.4 1.3 9.6 0.3 0.0 8.6 8.1 0.8 0.5 1.0 23.2 1.4 7.6 4.1 0.7 11.6 6.4 0.6 8.9 6.0 2.7 10.1 5.9 25.4 17.5 11.9 5.9 2.6 0.0 0.0 8.8 4.2 7.5 0.0 1.0 2.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 6.2 0.1 0.0 0.1 0.0 0.4 9.6 11.1 10.0 9.2 8.9 11.1 13.5 10.5 10.5 10.1 12.1 12.1 12.7 6.4 5.0 32.0 2.5 4.8 8.0 5.8 1.8 9.2 6.6 11.3 13.4 47.1 3.2 14.7 0.0 1.4 0.5 10.0 19.6 21.2 1.0 17.6 13.1 11.0 7.8 1.7 0.3 10.2 0.9 20.4 18.3 3.5 38.0 11.6 8.2 31.5 14.1 5.0 6.2 9.1 4.1 46.9 14.6 2.3 24.2 22.0 23.2 17.8 23.6 24.6 1.0 21.1 8.9 16.4 6.6 24.0 3.1 6.3 1.0 7.1 1.7 6.8 26.3 18.6 21.9 3.1 2.8 0.6 4.4 1.2 3.5 14.6 18.7 6.1 ARID4A "RBBP1, RBP-1, RBP1" ENSG00000032219 "AT-rich interaction domain 4A" P29374 14 58298504-58373887 "Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048899 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Plasma membrane, Cytosol" "HPA048899: " "unprognostic (1.57e-1)" "unprognostic (9.39e-2)" "unprognostic (5.17e-2)" "unprognostic (2.69e-1)" "unprognostic (3.70e-2)" "prognostic favorable (1.91e-4)" "unprognostic (2.71e-1)" "prognostic favorable (7.82e-4)" "unprognostic (2.08e-2)" "unprognostic (6.92e-2)" "unprognostic (3.27e-1)" "unprognostic (3.72e-2)" "unprognostic (9.32e-2)" "unprognostic (2.32e-1)" "unprognostic (2.64e-1)" "unprognostic (4.11e-2)" "unprognostic (3.52e-2)" 9.8 6.9 8.6 11.1 9.2 34.7 9.1 14.8 10.0 8.6 8.9 7.7 8.8 9.5 6.8 7.4 6.8 9.0 8.7 8.0 11.7 9.4 18.7 10.3 14.9 7.9 7.7 12.5 7.4 9.8 5.4 9.8 7.6 8.6 8.8 14.0 6.7 7.6 5.4 8.7 9.1 8.2 6.8 14.0 8.9 6.9 12.3 14.5 10.6 6.3 11.2 8.4 7.5 10.7 8.5 7.0 19.2 9.5 9.3 11.2 9.7 9.9 8.4 6.6 10.4 8.3 13.1 20.4 10.3 8.4 6.3 9.6 8.6 4.8 9.6 14.3 5.5 9.2 8.2 8.0 5.6 19.7 12.8 8.4 5.2 6.4 6.6 10.5 10.6 11.6 10.7 16.3 7.1 11.5 14.3 17.7 3.8 8.2 8.7 14.5 16.6 6.1 7.1 14.9 16.5 14.3 16.9 8.4 12.0 9.4 14.3 17.8 15.3 11.2 8.7 9.1 4.6 5.3 4.2 18.3 6.7 12.3 5.8 65.8 19.5 59.1 20.6 20.1 23.3 31.5 25.3 22.1 14.9 42.3 27.0 26.5 109.4 29.1 40.8 19.8 19.8 10.1 8.6 9.2 14.8 10.0 8.0 11.7 7.9 7.7 7.6 6.8 12.3 10.7 57.7 83.3 100.9 68.9 73.5 38.4 21.2 22.1 64.3 111.0 29.5 35.8 55.0 24.3 32.3 27.6 52.1 19.9 74.0 33.0 19.6 23.3 18.2 40.5 37.6 47.1 22.8 45.8 94.2 21.7 21.3 40.1 26.0 52.6 65.2 39.9 37.5 41.9 34.7 112.7 78.6 35.5 20.3 47.7 49.5 8.8 36.4 59.3 26.6 63.7 75.8 63.9 49.4 86.5 91.4 24.9 38.6 36.1 55.1 20.9 43.4 14.9 11.2 64.2 19.7 40.0 43.0 38.6 33.8 55.4 33.4 20.4 77.0 34.1 32.9 17.7 ARL11 "ARLTS1, FLJ33930" ENSG00000152213 "ADP ribosylation factor like GTPase 11" Q969Q4 13 49628507-49633872 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.9" "Cell type enhanced" "Detected in many" "B-cells: 18.2;Hofbauer cells: 31.3;Kupffer cells: 34.8;Macrophages: 18.2;monocytes: 19.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 38.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 7.9;HMC-1: 10.7;NB-4: 11.1;THP-1: 14.5;U-698: 6.6;U-937: 6.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040855, HPA040887" Uncertain Approved "Intermediate filaments,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Intermediate filaments, Cytosol" "HPA040855: AB_10793864, HPA040887: AB_10796229" "unprognostic (1.19e-2)" "unprognostic (2.27e-1)" "unprognostic (2.07e-1)" "unprognostic (2.82e-1)" "unprognostic (7.86e-2)" "unprognostic (1.46e-1)" "unprognostic (1.12e-2)" "unprognostic (1.83e-1)" "unprognostic (3.60e-1)" "unprognostic (1.82e-1)" "unprognostic (2.72e-2)" "unprognostic (2.55e-1)" "unprognostic (2.27e-4)" "unprognostic (1.72e-2)" "unprognostic (5.60e-2)" "unprognostic (1.16e-1)" "unprognostic (3.14e-2)" 0.8 0.8 0.5 3.9 0.5 3.5 0.7 0.6 0.7 0.6 0.8 1.0 1.2 0.2 0.2 1.0 0.3 1.1 0.4 0.4 0.6 0.1 0.6 2.2 6.9 1.0 0.7 0.2 0.1 0.3 0.3 1.9 0.8 0.2 1.5 0.1 0.6 0.2 0.3 0.6 1.9 0.7 0.7 4.8 0.6 0.3 1.0 3.7 0.4 0.4 3.9 1.3 0.8 1.2 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.6 0.0 7.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.1 0.1 0.6 0.0 5.2 10.7 0.1 0.1 0.0 0.0 0.0 0.4 5.1 0.3 0.1 0.0 1.3 4.9 11.1 0.1 0.0 0.0 5.3 0.0 2.2 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.1 3.5 14.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 6.6 0.0 6.3 0.0 21.8 15.3 16.3 0.1 17.9 0.2 7.9 0.3 0.3 8.1 10.1 0.8 0.4 38.0 0.8 13.4 8.6 0.3 4.4 0.5 0.5 0.6 0.7 0.4 0.6 1.0 0.7 0.8 0.7 1.0 1.2 0.9 0.0 1.1 0.0 18.2 0.3 0.3 0.2 1.2 0.7 1.0 0.9 0.6 2.8 0.0 0.0 0.0 4.7 3.4 1.7 0.0 0.0 1.7 0.1 0.1 1.2 1.2 6.9 0.0 0.0 5.1 0.3 0.0 0.1 7.6 0.0 1.8 0.6 31.3 0.0 0.0 3.4 0.0 34.8 3.5 1.3 0.3 18.2 0.0 3.7 19.2 0.3 1.0 0.0 0.1 0.1 10.2 0.0 2.9 0.1 4.2 0.1 2.3 0.5 0.0 0.3 0.2 1.5 0.3 4.1 0.0 1.5 1.2 0.5 3.1 0.4 ARMC9 "ARM, FLJ12584, KIAA1868, KU-MEL-1" ENSG00000135931 "Armadillo repeat containing 9" Q7Z3E5 2 231198546-231376848 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 48.6;retina: 71.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 310.6;Excitatory neurons: 112.5;monocytes: 116.4;Rod photoreceptor cells: 202.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 15.5" "Immune cell enhanced" "Detected in some" "NK-cell: 2.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 275.2;SK-MEL-30: 222.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019041, HPA026671" Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA019041: AB_1845035, HPA026671: AB_1845036" "unprognostic (2.90e-1)" "unprognostic (2.86e-1)" "unprognostic (5.35e-2)" "unprognostic (6.26e-2)" "unprognostic (1.99e-2)" "unprognostic (5.57e-2)" "unprognostic (7.20e-4)" "unprognostic (1.58e-2)" "unprognostic (4.85e-2)" "unprognostic (7.17e-3)" "unprognostic (4.14e-1)" "unprognostic (9.15e-2)" "unprognostic (7.43e-2)" "unprognostic (1.30e-2)" "unprognostic (4.19e-2)" "unprognostic (5.57e-2)" "prognostic unfavorable (7.66e-5)" 2.3 15.0 4.0 5.4 5.3 1.9 3.3 1.1 15.5 5.6 48.6 14.7 1.7 19.5 5.6 4.2 8.7 7.7 2.3 5.9 1.9 5.2 0.8 7.1 1.6 0.4 2.4 9.4 3.7 10.8 11.1 5.7 0.1 5.5 5.2 71.5 3.2 6.6 1.0 2.6 6.5 23.5 0.0 1.1 8.9 9.4 0.2 3.0 7.6 1.1 2.1 6.8 2.7 1.7 21.2 10.8 20.3 15.1 14.5 23.7 8.3 23.3 275.2 28.6 35.8 3.1 10.3 2.7 11.0 68.3 46.6 12.2 24.8 22.7 25.0 1.7 15.2 1.5 14.0 11.6 41.3 5.0 5.1 63.8 8.8 38.3 13.7 73.3 21.7 12.2 4.7 0.6 46.0 29.9 6.3 6.9 44.4 7.7 12.0 7.8 18.2 0.3 30.6 6.9 15.6 32.2 9.3 25.2 222.7 17.8 9.7 5.4 22.6 17.6 10.9 10.0 10.4 24.8 6.2 1.3 33.9 1.0 17.7 1.1 0.2 0.3 0.2 0.1 0.1 0.6 0.2 0.3 0.2 0.3 0.3 0.3 0.5 2.6 0.2 0.3 0.2 0.2 4.0 5.3 1.1 15.5 5.9 1.9 0.4 2.4 0.1 0.0 0.2 1.7 1.3 3.2 36.1 25.8 1.4 1.8 5.6 6.8 1.2 24.0 5.1 5.7 3.3 2.8 7.5 3.7 310.6 4.8 0.1 4.0 1.9 7.3 69.5 25.1 22.3 4.9 7.8 1.3 112.5 17.3 3.0 7.2 3.6 4.1 3.8 6.6 2.5 1.0 10.6 1.7 62.7 6.0 0.0 0.3 2.4 23.8 14.0 6.6 19.6 17.8 116.4 16.7 1.0 25.6 14.1 11.5 1.8 21.4 1.1 1.9 0.7 5.1 31.3 202.4 6.6 5.3 6.4 36.7 15.7 0.6 0.9 2.2 1.3 6.3 10.0 2.1 ARMCX1 "ALEX1, GASP7" ENSG00000126947 "Armadillo repeat containing X-linked 1" Q9P291 X 101550547-101554700 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 7.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 74.9;ASC TERT1: 66.9;BJ hTERT+ SV40 Large T+ RasG12V: 78.2;LHCN-M2: 70.7;RH-30: 87.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000268, HPA005685, CAB020695" Supported Supported Nucleoplasm,Mitochondria,Cytosol No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria "Nucleoplasm, Cytosol" "CAB020695: , HPA000268: , HPA005685: AB_10600781" "unprognostic (2.31e-1)" "prognostic unfavorable (3.62e-4)" "unprognostic (2.65e-2)" "unprognostic (2.32e-2)" "unprognostic (2.25e-2)" "unprognostic (2.39e-1)" "unprognostic (2.18e-3)" "unprognostic (2.13e-1)" "unprognostic (1.23e-1)" "unprognostic (1.02e-1)" "prognostic favorable (7.32e-5)" "unprognostic (1.02e-1)" "unprognostic (2.85e-2)" "unprognostic (2.20e-3)" "unprognostic (8.77e-2)" "unprognostic (2.12e-2)" "unprognostic (1.09e-2)" 24.4 34.0 16.8 8.8 18.4 3.1 21.9 14.9 21.9 32.3 18.2 31.4 7.0 30.4 21.2 11.4 25.2 17.5 32.8 18.0 19.5 13.7 4.0 16.5 5.5 16.2 17.9 48.3 12.8 16.9 25.9 14.9 18.8 24.3 7.6 12.0 14.1 23.0 27.7 10.9 12.0 21.2 15.6 14.1 14.8 5.9 17.7 6.3 16.4 25.5 3.4 23.2 21.7 17.9 2.1 0.6 16.0 0.0 74.9 66.9 0.2 25.5 49.7 31.4 78.2 0.0 0.4 0.0 21.3 39.3 34.2 2.1 0.0 3.7 17.7 0.1 0.0 14.9 5.1 0.0 39.6 0.0 0.2 56.5 4.8 23.8 0.0 25.9 19.2 0.0 0.3 0.3 70.7 1.0 0.0 0.1 23.1 0.0 0.2 0.0 87.8 0.1 21.6 0.0 15.8 13.1 0.0 0.3 45.9 4.4 2.5 11.0 25.6 18.9 10.0 55.5 0.3 0.0 0.3 0.0 18.6 0.0 12.1 0.0 3.3 0.4 0.0 3.1 0.5 0.0 0.4 0.3 7.7 0.2 1.1 2.7 0.1 1.8 0.9 4.0 0.8 1.6 16.8 18.4 14.9 21.9 18.0 19.5 16.2 17.9 18.8 15.6 17.7 17.9 27.6 25.6 7.4 8.5 0.7 33.1 22.9 5.0 18.2 32.2 19.1 17.4 59.7 7.2 4.1 23.9 6.2 1.6 3.7 0.6 13.7 21.1 0.3 10.4 23.2 29.9 5.4 4.2 9.5 7.1 2.6 53.2 9.2 11.2 24.1 20.0 20.7 0.8 27.9 21.9 11.8 2.2 2.0 9.5 33.4 2.0 47.2 17.5 58.7 4.7 5.7 36.0 0.0 11.1 8.4 5.6 0.1 44.4 0.4 20.6 0.6 13.6 3.6 13.9 46.0 60.6 39.9 1.6 0.7 3.8 21.7 2.6 2.3 35.6 2.5 7.5 ASAP1 "CENTB4, DDEF1, KIAA1249, PAP, ZG14P" ENSG00000153317 "ArfGAP with SH3 domain, ankyrin repeat and PH domain 1" Q9ULH1 8 130052104-130443674 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 345.8;Late spermatids: 460.2;Oligodendrocyte precursor cells: 622.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 11.6" "Group enriched" "Detected in many" 5 "dendritic cells: 3.7;granulocytes: 11.6;monocytes: 6.7" "Cell line enhanced" "Detected in all" "TIME: 167.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011136, CAB037292, HPA048565" Approved Approved "Plasma membrane,Centrosome,Cytosol" NA NA 31000 "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Centrosome, Cytosol" "CAB037292: AB_476723, HPA011136: AB_2668438, HPA048565: AB_2680445" "unprognostic (1.20e-2)" "unprognostic (1.15e-2)" "unprognostic (7.68e-2)" "prognostic unfavorable (5.81e-5)" "unprognostic (1.77e-1)" "unprognostic (3.33e-2)" "prognostic unfavorable (5.63e-8)" "prognostic unfavorable (3.56e-5)" "unprognostic (3.34e-1)" "unprognostic (5.27e-2)" "unprognostic (8.56e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.50e-7)" "unprognostic (3.79e-2)" "unprognostic (1.19e-1)" "unprognostic (7.38e-2)" "unprognostic (1.22e-3)" 35.1 22.2 13.5 12.2 15.1 47.8 24.0 7.6 22.0 17.6 3.9 13.4 5.5 19.0 12.2 10.7 17.2 14.6 24.7 14.7 10.5 11.9 9.3 30.1 18.0 14.2 20.9 18.2 7.8 18.1 10.5 27.8 16.5 12.7 8.9 8.6 8.5 11.4 13.4 17.3 12.2 17.9 9.4 30.0 10.6 28.5 29.1 16.3 16.4 10.4 19.0 15.9 15.6 17.1 48.9 31.5 41.1 27.4 46.7 61.9 37.1 44.2 83.8 57.2 62.3 17.5 18.2 14.4 31.8 67.7 38.6 13.2 24.7 41.4 86.3 20.6 15.9 22.6 20.7 23.6 119.9 10.4 6.7 61.7 15.3 33.6 50.3 66.9 60.2 7.7 13.0 45.7 54.0 15.1 13.3 9.8 13.1 24.1 30.5 13.6 9.6 7.0 18.1 25.2 14.6 44.4 32.4 20.5 26.5 42.5 17.0 22.4 167.5 45.9 28.9 20.6 69.8 42.2 12.0 9.7 34.6 14.6 50.3 0.0 2.2 1.5 0.5 2.1 0.3 1.3 1.0 0.9 3.7 1.0 1.3 0.8 11.6 0.6 6.7 0.4 0.8 1.1 13.5 15.1 7.6 22.0 14.7 10.5 14.2 20.9 16.5 9.4 29.1 17.1 97.2 3.2 6.3 206.6 22.7 47.7 21.9 12.0 29.6 25.0 12.4 14.7 33.7 27.1 11.5 3.7 16.7 42.2 14.6 3.6 3.9 10.5 159.7 14.3 34.2 109.1 13.1 98.9 345.8 8.7 37.6 43.7 4.6 27.7 9.5 30.1 103.9 8.2 64.0 62.2 225.8 4.3 8.2 56.1 168.8 460.2 39.1 73.1 44.4 181.8 71.4 9.5 15.5 622.3 245.9 12.5 4.7 54.9 13.7 37.9 5.8 4.3 4.2 7.8 78.9 28.5 90.1 61.4 95.5 25.2 44.9 46.7 23.1 58.9 4.8 22.0 ASIC1 "ACCN2, BNaC2, hBNaC2" ENSG00000110881 "Acid sensing ion channel subunit 1" P78348 12 50057548-50083611 "Predicted membrane proteins" "Calcium transport, Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.9" "Cell type enhanced" "Detected in some" "Astrocytes: 31.3;Inhibitory neurons: 16.4;Oligodendrocyte precursor cells: 64.8;Oligodendrocytes: 11.2" "Cancer enhanced" "Detected in many" "glioma: 12.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 34.8;SH-SY5Y: 27.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058870 Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 68: Oligodendrocytes - Mixed function" "Golgi apparatus, Plasma membrane" "HPA058870: AB_2683841" "unprognostic (5.32e-3)" "unprognostic (1.70e-1)" "unprognostic (4.00e-2)" "unprognostic (3.56e-2)" "unprognostic (2.41e-1)" "unprognostic (3.48e-3)" "unprognostic (2.92e-3)" "unprognostic (3.00e-2)" "unprognostic (1.72e-1)" "unprognostic (9.37e-2)" "unprognostic (2.34e-2)" "unprognostic (2.86e-3)" "unprognostic (6.97e-7)" "unprognostic (7.19e-2)" "unprognostic (3.73e-1)" "unprognostic (2.78e-3)" "unprognostic (8.27e-5)" 1.6 0.7 19.3 0.9 22.2 0.1 1.6 14.4 19.8 3.2 6.4 6.3 0.8 1.9 0.0 2.3 3.0 2.5 2.6 18.2 21.0 0.7 0.2 0.6 0.4 18.0 24.9 1.1 0.5 5.0 0.8 0.6 15.9 2.8 1.2 1.0 3.5 1.9 0.3 0.9 2.5 2.3 13.7 0.3 2.8 0.7 23.7 1.5 0.5 0.0 0.2 1.9 1.7 13.8 3.3 7.2 8.7 19.7 2.7 4.2 4.9 2.2 6.1 4.0 4.0 4.8 2.3 2.1 4.7 1.1 2.4 3.2 8.7 7.7 2.3 1.9 25.1 6.2 9.0 3.2 3.8 9.5 22.7 10.7 3.7 0.4 1.0 34.8 0.5 22.8 4.3 0.0 3.3 4.0 8.8 18.3 3.9 6.9 12.5 9.3 8.5 4.0 2.0 0.1 13.4 27.4 5.3 1.8 3.2 1.4 11.0 6.5 0.3 4.1 12.8 2.5 1.2 0.1 0.0 0.0 5.1 7.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 22.2 14.4 19.8 18.2 21.0 18.0 24.9 15.9 13.7 23.7 13.8 0.3 0.0 0.0 31.3 0.0 0.0 0.4 0.5 0.0 2.8 2.0 2.8 0.9 0.0 2.1 1.8 0.0 0.4 0.1 0.1 0.0 0.2 0.1 0.0 0.7 0.1 0.0 0.0 7.0 0.0 0.9 3.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 3.3 16.4 0.1 0.0 0.0 0.3 0.0 1.5 0.1 0.0 1.9 0.0 1.4 0.0 64.8 11.2 0.2 0.0 1.2 0.2 0.5 0.0 3.2 6.0 0.5 0.0 1.3 0.7 0.1 0.9 2.3 0.0 0.3 0.9 0.4 0.0 0.2 ASTN2 KIAA0634 ENSG00000148219 "Astrotactin 2" O75129 9 116423112-117415070 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 39.2" "Cell type enhanced" "Detected in many" "Astrocytes: 354.6;Excitatory neurons: 370.0;Inhibitory neurons: 1011.0;Late spermatids: 228.2;Oligodendrocyte precursor cells: 900.3;Oligodendrocytes: 225.9" "Cancer enhanced" "Detected in all" "prostate cancer: 15.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SH-SY5Y: 37.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027035 Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Nucleoplasm "HPA027035: AB_1845122" "unprognostic (3.25e-2)" "unprognostic (2.70e-2)" "unprognostic (7.41e-3)" "unprognostic (5.42e-3)" "unprognostic (1.89e-1)" "unprognostic (2.67e-2)" "unprognostic (1.55e-1)" "unprognostic (1.02e-2)" "unprognostic (2.94e-1)" "unprognostic (2.80e-1)" "unprognostic (3.40e-2)" "unprognostic (2.93e-1)" "prognostic favorable (6.66e-16)" "unprognostic (3.28e-1)" "unprognostic (2.01e-1)" "unprognostic (1.63e-1)" "unprognostic (1.57e-1)" 3.3 9.8 26.1 2.7 26.3 3.6 4.3 39.0 36.0 5.3 9.0 5.2 3.4 3.2 3.9 2.2 8.0 2.5 22.5 27.0 25.8 5.5 4.1 2.2 2.4 29.3 36.2 2.8 6.7 3.1 11.6 1.8 28.7 25.2 3.2 13.4 5.8 11.3 7.3 2.4 4.1 2.8 21.4 2.4 5.6 17.6 35.0 6.0 1.8 5.6 1.8 3.2 3.5 39.2 3.7 12.0 4.3 7.1 7.6 7.0 15.4 5.7 2.3 2.5 2.8 8.1 4.4 8.8 6.1 3.8 9.3 1.3 11.5 0.6 3.1 4.8 2.9 3.1 5.8 17.0 3.0 1.8 6.2 9.5 1.1 7.8 0.7 5.4 1.8 10.5 3.9 5.9 7.9 3.8 4.1 1.4 13.2 10.6 6.4 4.9 27.5 2.5 8.0 12.3 6.3 37.9 6.8 2.0 4.8 14.5 15.5 1.3 3.5 5.9 9.1 5.6 4.9 9.0 5.0 8.3 10.5 2.0 25.8 2.5 0.4 0.5 2.8 0.3 3.6 1.5 3.1 2.4 0.2 1.6 3.0 2.5 1.9 5.9 0.6 0.9 8.8 1.0 26.1 26.3 39.0 36.0 27.0 25.8 29.3 36.2 28.7 21.4 35.0 39.2 0.6 6.4 8.9 354.6 1.1 1.3 3.2 0.4 1.2 4.9 4.2 4.8 22.7 2.8 5.0 1.8 10.4 0.4 1.0 0.4 3.9 0.8 122.5 4.7 5.5 1.3 12.6 0.4 370.0 1.1 0.4 4.9 4.1 0.7 6.3 37.0 0.7 2.9 3.2 10.1 1011.0 1.0 0.0 0.0 1.6 228.2 2.8 1.0 0.0 36.5 0.2 3.0 0.0 900.3 225.9 0.5 2.1 5.7 3.6 11.7 5.7 6.9 11.7 5.1 0.0 1.9 2.0 7.7 13.2 0.3 0.6 0.3 3.8 1.9 1.8 2.2 ATE1 ENSG00000107669 "Arginyltransferase 1" O95260 10 121740424-121928492 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 137.7;Oligodendrocytes: 220.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038444, HPA057549" Approved Supported Nucleoplasm NA NA 83000 "Cluster 18: Basophils - Vesicular transport" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA038444: AB_10672745, HPA057549: AB_2683463" "unprognostic (1.37e-1)" "unprognostic (5.19e-2)" "unprognostic (2.75e-3)" "unprognostic (2.40e-1)" "unprognostic (4.67e-2)" "unprognostic (6.65e-3)" "unprognostic (1.85e-1)" "unprognostic (1.42e-1)" "unprognostic (1.71e-1)" "unprognostic (1.00e-1)" "unprognostic (2.52e-1)" "unprognostic (5.69e-2)" "prognostic favorable (2.67e-4)" "unprognostic (3.20e-1)" "unprognostic (8.08e-2)" "unprognostic (2.16e-1)" "unprognostic (1.02e-1)" 10.1 11.7 8.1 8.5 8.5 7.4 10.4 7.3 9.2 12.1 17.3 13.5 11.4 10.6 8.4 10.7 9.0 10.4 22.2 8.4 11.0 18.2 18.2 9.5 9.5 6.7 7.3 10.0 6.2 15.4 4.8 11.0 7.5 12.7 14.6 15.6 7.8 10.0 18.3 6.7 11.1 11.7 7.4 10.4 8.8 13.3 10.6 13.0 16.0 15.4 10.6 12.7 6.6 8.7 13.0 19.5 15.4 15.0 15.1 16.8 12.3 12.0 24.0 13.1 13.2 23.6 19.1 16.1 9.5 14.3 8.8 16.1 14.5 14.2 16.3 20.3 13.1 5.8 8.8 31.1 15.5 26.7 13.4 11.9 15.2 13.8 32.0 19.3 18.7 9.0 7.8 29.4 14.5 7.9 14.0 15.2 7.5 19.6 11.4 13.1 18.1 10.6 23.4 11.2 4.8 19.4 17.2 12.9 28.2 11.3 8.9 9.2 19.2 8.2 7.0 12.5 21.1 28.0 33.6 12.0 12.6 20.6 7.4 12.8 3.8 6.1 5.3 4.5 6.3 4.5 5.0 5.3 3.4 4.2 5.5 5.6 2.3 5.1 3.5 4.8 6.7 4.0 8.1 8.5 7.3 9.2 8.4 11.0 6.7 7.3 7.5 7.4 10.6 8.7 23.0 9.6 22.0 76.4 17.3 8.4 12.8 9.4 24.5 31.3 17.5 14.6 75.6 11.5 12.7 20.2 12.5 7.2 20.9 42.8 17.6 11.3 6.5 15.8 19.4 19.3 22.1 16.2 100.5 13.3 10.5 25.0 29.6 16.4 12.6 13.5 20.0 26.6 10.0 23.5 93.8 17.7 10.2 14.8 7.2 7.7 20.5 23.6 14.2 74.0 12.8 21.7 27.8 137.7 220.4 15.6 18.3 25.9 24.8 21.0 19.5 39.4 11.5 35.8 0.0 23.4 21.1 26.9 40.2 30.7 17.5 8.6 17.9 29.1 16.8 16.6 ATG9B "APG9L2, FLJ14885, NOS3AS, SONE" ENSG00000181652 "Autophagy related 9B" Q674R7 7 151012209-151024499 "Metabolic proteins, Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 8.3;skin 1: 11.5" "Cell type enhanced" "Detected in many" "Early spermatids: 50.7;Endometrial ciliated cells: 28.6;Late spermatids: 30.3;Respiratory ciliated cells: 25.9;Syncytiotrophoblasts: 115.5" "Cancer enhanced" "Detected in many" "testis cancer: 6.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 8.9" "Lineage enriched" "Detected in many" 5 "T-cells: 8.9" "Group enriched" "Detected in some" 5 "BEWO: 13.0;CAPAN-2: 4.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (1.59e-1)" "unprognostic (2.18e-2)" "unprognostic (1.31e-1)" "unprognostic (5.03e-2)" "unprognostic (1.53e-3)" "unprognostic (1.05e-3)" "unprognostic (2.79e-3)" "unprognostic (6.66e-2)" "unprognostic (2.38e-3)" "unprognostic (6.76e-2)" "unprognostic (2.02e-1)" "unprognostic (5.06e-2)" "unprognostic (2.08e-6)" "unprognostic (2.82e-2)" "unprognostic (2.70e-2)" "unprognostic (6.34e-2)" "unprognostic (2.63e-1)" 0.0 0.5 1.1 0.4 1.7 0.2 0.2 0.4 1.0 1.7 0.3 0.0 0.0 0.4 1.1 8.3 1.0 0.2 0.0 0.5 2.1 0.0 0.0 0.2 0.8 2.0 1.7 0.1 0.0 0.0 1.5 4.1 1.1 0.2 0.0 0.8 0.5 0.0 0.2 11.5 0.0 0.0 1.0 0.1 0.1 2.0 2.1 0.3 0.1 0.0 0.8 0.1 1.6 0.4 0.6 0.0 0.7 0.1 0.0 0.0 13.0 0.0 0.0 0.0 0.0 0.1 4.2 0.3 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.6 0.2 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 1.5 0.4 0.6 0.0 1.1 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.2 1.1 0.0 1.0 0.9 5.0 1.3 0.0 1.6 8.9 3.4 0.0 0.4 0.1 0.7 5.4 1.4 1.1 1.7 0.4 1.0 0.5 2.1 2.0 1.7 1.1 1.0 2.1 0.4 0.4 0.0 0.0 0.0 2.8 0.0 0.2 1.9 0.6 4.0 0.7 0.9 1.4 1.5 1.6 0.0 0.0 10.2 1.5 0.3 0.0 0.3 50.7 28.6 3.3 1.1 0.0 0.0 2.7 0.2 2.5 0.5 0.0 15.4 14.7 7.8 2.2 0.0 1.9 0.0 7.7 0.0 4.1 0.3 0.4 30.3 0.6 0.8 0.0 0.0 0.3 0.5 1.0 0.5 0.6 3.8 0.0 0.7 0.4 0.3 0.0 0.1 25.9 0.6 0.0 0.0 0.9 19.8 12.7 0.8 0.3 115.5 4.7 0.1 0.2 1.9 ATN1 "B37, D12S755E, DRPLA" ENSG00000111676 "Atrophin 1" P54259 12 6924463-6942321 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Disease variant, Epilepsy, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031619 Enhanced Enhanced Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA031619: AB_10601667" "unprognostic (3.86e-3)" "unprognostic (2.07e-1)" "unprognostic (1.80e-3)" "unprognostic (5.82e-2)" "unprognostic (1.37e-1)" "unprognostic (1.95e-1)" "prognostic unfavorable (7.20e-4)" "unprognostic (1.44e-1)" "unprognostic (6.90e-2)" "unprognostic (8.42e-3)" "unprognostic (1.86e-2)" "unprognostic (3.19e-1)" "unprognostic (7.43e-2)" "unprognostic (5.46e-2)" "unprognostic (9.49e-2)" "unprognostic (3.95e-1)" "unprognostic (7.35e-2)" 125.2 148.3 71.7 33.7 60.1 6.9 120.6 94.2 120.0 143.8 14.5 155.4 36.3 146.4 25.5 71.9 148.9 43.2 94.2 66.8 75.7 95.5 42.7 109.0 20.4 81.3 70.6 234.6 79.6 56.7 188.9 43.8 60.0 117.6 21.1 58.8 89.8 59.5 81.9 79.2 82.0 49.4 41.2 74.2 100.4 33.3 71.5 16.3 189.0 34.4 14.0 122.2 108.8 67.4 56.4 72.1 75.9 154.7 69.6 61.7 126.3 65.5 55.4 65.1 45.8 73.6 65.6 15.2 20.4 80.8 54.1 36.8 46.2 63.8 33.3 178.0 46.3 70.6 71.7 35.6 108.3 14.6 103.8 101.8 46.1 82.4 63.6 112.5 64.4 22.4 61.1 29.9 58.2 81.2 31.9 13.5 156.0 26.2 30.1 65.9 40.6 11.2 48.3 78.3 23.4 75.3 66.5 77.2 47.1 73.6 29.5 40.3 85.2 76.7 97.9 61.1 102.2 22.7 8.1 10.7 60.1 18.7 82.3 0.5 0.1 0.7 0.6 0.0 0.5 0.7 0.2 0.3 0.1 0.5 0.3 0.4 0.0 0.1 0.0 0.5 0.3 0.2 71.7 60.1 94.2 120.0 66.8 75.7 81.3 70.6 60.0 41.2 71.5 67.4 66.3 16.0 17.2 76.4 9.1 30.2 13.5 22.9 30.1 26.6 51.5 57.4 16.4 24.3 20.4 29.5 18.8 27.4 11.4 37.4 15.6 20.5 2.3 39.9 61.2 40.7 21.7 4.8 23.8 30.3 15.3 30.9 34.7 51.7 10.1 37.1 39.7 8.0 11.9 25.2 29.7 23.0 8.2 10.9 21.0 3.5 63.6 13.7 21.4 23.4 4.8 17.3 3.1 17.6 18.2 29.9 25.3 52.6 9.5 17.4 24.2 12.1 15.4 23.9 19.7 29.4 39.5 9.7 7.7 22.1 24.9 37.1 10.9 26.2 20.4 17.9 ATOX1 HAH1 ENSG00000177556 "Antioxidant 1 copper chaperone" O00244 5 151742316-151772532 "Predicted intracellular proteins" "Copper transport, Ion transport, Transport" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 932.7;Proximal tubular cells: 1449.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055036 Approved "Nucleoplasm,Plasma membrane" NA NA 790000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Plasma membrane" "HPA055036: " "unprognostic (5.55e-2)" "unprognostic (1.60e-1)" "unprognostic (3.84e-1)" "unprognostic (1.82e-1)" "unprognostic (8.11e-2)" "unprognostic (3.34e-2)" "unprognostic (2.33e-1)" "unprognostic (8.60e-2)" "unprognostic (3.58e-2)" "unprognostic (2.53e-2)" "prognostic favorable (9.57e-4)" "unprognostic (2.72e-1)" "unprognostic (7.15e-2)" "unprognostic (8.18e-2)" "unprognostic (2.57e-2)" "unprognostic (1.87e-1)" "unprognostic (2.22e-1)" 102.0 136.9 173.3 65.9 183.6 73.8 100.1 180.8 201.1 84.4 181.9 84.7 81.8 73.7 98.0 112.1 64.6 63.6 107.4 170.0 189.7 217.1 260.9 80.3 142.9 181.9 184.7 57.8 57.1 180.6 81.2 69.8 183.6 100.2 64.3 24.9 93.0 74.6 53.6 102.8 83.0 75.9 184.9 124.4 76.1 72.9 185.6 82.6 119.3 39.5 128.2 91.7 84.2 192.8 112.0 181.9 104.4 73.1 275.1 224.2 136.6 197.7 225.8 197.2 267.3 248.2 235.8 224.9 233.3 345.7 437.1 102.4 129.2 502.5 161.3 143.9 220.3 98.7 118.4 255.1 254.1 137.5 108.5 291.3 105.0 246.0 161.1 144.7 295.3 138.5 83.4 642.7 305.1 276.6 102.3 304.0 59.8 249.8 382.3 61.4 120.0 350.0 190.6 98.1 136.2 80.0 169.3 476.6 763.4 117.2 234.2 165.3 328.5 201.0 159.4 246.9 345.9 522.6 513.4 136.2 271.7 92.3 846.1 154.6 207.9 199.4 75.1 247.6 69.0 98.6 67.3 66.2 171.3 68.3 53.0 58.0 155.3 97.0 177.2 217.8 103.5 117.3 173.3 183.6 180.8 201.1 170.0 189.7 181.9 184.7 183.6 184.9 185.6 192.8 209.1 57.7 56.6 8.1 93.2 67.7 79.8 204.5 70.0 22.7 250.1 246.5 112.1 165.8 102.2 211.5 14.6 146.0 65.6 213.6 541.9 207.6 178.9 121.1 171.1 183.2 150.7 104.1 6.4 159.1 218.7 127.3 96.8 135.3 73.0 117.8 236.7 932.7 671.2 25.2 9.1 171.1 164.8 221.4 166.0 321.1 83.0 230.4 238.3 4.7 436.7 185.7 88.6 5.5 22.7 318.1 238.7 103.4 170.4 124.2 727.0 1449.1 108.5 24.9 92.1 69.0 235.2 81.9 156.0 153.1 106.4 118.8 55.4 96.6 152.7 122.2 ATP23 "KUB3, XRCC6BP1" ENSG00000166896 "ATP23 metallopeptidase and ATP synthase assembly factor homolog" Q9Y6H3 12 57906039-57959148 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.8" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 12.7;Cytotrophoblasts: 14.4;Distal tubular cells: 17.6;Extravillous trophoblasts: 15.2;Proximal tubular cells: 26.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.6" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.6" "Cell line enhanced" "Detected in some" "A549: 1.0;Karpas-707: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035804, HPA043204" Uncertain Enhanced "Vesicles,Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Plasma membrane" "Cell Junctions, Cytosol" "HPA035804: AB_10601026, HPA043204: AB_2678361" "unprognostic (2.56e-1)" "unprognostic (1.31e-2)" "unprognostic (8.82e-2)" "unprognostic (2.92e-2)" "unprognostic (2.30e-2)" "unprognostic (6.16e-2)" "unprognostic (1.20e-1)" "unprognostic (5.28e-2)" "unprognostic (5.41e-3)" "unprognostic (1.03e-2)" "unprognostic (1.24e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.44e-5)" "unprognostic (4.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.80e-1)" "unprognostic (2.27e-1)" 7.5 4.9 0.6 0.4 0.5 0.1 5.6 0.6 0.9 4.1 0.5 8.1 0.2 3.1 0.0 5.6 3.2 0.0 4.6 1.0 0.3 4.0 5.2 2.6 0.1 0.4 0.2 3.1 5.9 0.0 2.8 0.1 0.4 3.3 0.0 0.5 3.6 0.0 12.4 4.4 4.3 0.0 0.3 3.2 4.2 27.8 0.5 0.0 3.5 0.0 0.1 4.7 4.0 0.3 0.6 1.0 0.0 0.3 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.9 0.2 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.6 2.6 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.3 0.6 0.8 0.1 0.0 0.4 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.3 0.0 0.4 0.0 0.0 0.4 0.0 0.6 0.1 0.2 0.0 0.2 0.2 0.2 0.2 0.1 0.3 0.0 0.3 0.2 0.2 1.6 0.1 0.1 0.1 0.1 0.0 0.6 0.5 0.6 0.9 1.0 0.3 0.4 0.2 0.4 0.3 0.5 0.3 8.0 0.0 9.2 0.0 2.3 0.0 0.0 0.0 0.0 0.0 7.4 12.7 0.0 0.0 1.8 3.7 0.0 14.4 4.2 0.0 17.6 6.1 0.0 5.6 4.9 2.8 0.0 0.0 0.0 10.7 15.2 2.3 0.0 6.0 11.4 6.8 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.9 0.0 0.0 26.1 0.7 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 3.4 3.0 9.5 0.0 0.0 ATP2A3 SERCA3 ENSG00000074370 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3" Q93084 17 3923870-3964464 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 101.5;salivary gland: 185.3" "Cell type enhanced" "Detected in many" "B-cells: 82.5;Distal enterocytes: 120.7;Enteroendocrine cells: 97.8;Gastric mucus-secreting cells: 153.4;Intestinal goblet cells: 128.4;Plasma cells: 96.0;Undifferentiated cells: 65.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 186.8;HMC-1: 266.1;JURKAT: 152.1;MOLT-4: 253.2;SK-BR-3: 195.2" "Region enriched" "Detected in all" 15 "cerebellum: 67.2" "Low region specificity" "Detected in all" "HPA007180, CAB010882" Approved NA NA 5400000 "Cluster 52: Eosinophils - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "CAB010882: AB_258368, HPA007180: AB_1845177" "unprognostic (4.14e-2)" "prognostic favorable (4.69e-5)" "unprognostic (1.21e-2)" "unprognostic (3.68e-2)" "unprognostic (1.02e-2)" "prognostic favorable (2.51e-4)" "unprognostic (8.83e-3)" "unprognostic (2.30e-1)" "unprognostic (8.29e-2)" "unprognostic (3.67e-3)" "unprognostic (3.95e-3)" "unprognostic (1.73e-1)" "unprognostic (1.45e-3)" "unprognostic (1.60e-1)" "unprognostic (3.25e-2)" "unprognostic (1.54e-1)" "unprognostic (1.97e-3)" 6.8 13.7 6.8 62.2 8.7 98.3 7.7 20.0 6.1 6.0 15.3 55.0 30.7 9.1 1.6 9.7 6.1 13.7 8.0 3.0 4.5 11.4 4.6 22.4 101.5 2.3 12.8 3.1 64.0 2.1 2.5 2.8 3.9 20.3 33.0 0.2 185.3 19.6 3.3 28.2 75.3 6.3 2.0 98.2 92.8 2.1 11.6 97.5 11.7 3.3 58.7 17.0 7.2 2.3 0.3 7.6 0.3 6.8 0.0 0.0 0.3 0.4 0.9 0.2 0.6 2.5 1.7 186.8 11.0 0.6 0.1 0.8 3.1 0.0 0.0 23.5 2.1 98.0 6.0 0.1 1.7 108.0 266.1 0.2 0.0 0.7 0.0 0.1 0.3 152.1 20.1 117.1 0.1 116.8 253.2 115.5 1.2 53.1 1.6 27.5 0.2 43.3 0.0 3.3 11.5 3.4 1.5 195.2 0.2 1.1 12.2 26.3 0.5 0.0 2.1 0.4 0.1 43.4 14.2 66.0 2.5 75.6 0.1 16.0 1.4 33.7 10.8 0.9 8.3 9.8 6.7 10.3 1.6 11.4 4.8 6.0 13.1 3.8 0.5 15.8 6.4 6.7 6.8 8.7 20.0 6.1 3.0 4.5 2.3 12.8 3.9 2.0 11.6 2.3 7.1 0.0 1.9 0.7 82.5 0.9 0.4 0.7 1.2 0.0 4.7 1.7 3.8 2.8 2.7 23.9 0.0 0.2 59.2 120.7 0.0 1.3 0.1 0.3 0.4 7.8 97.8 22.5 0.5 12.1 0.3 1.9 153.4 0.3 33.0 0.2 8.9 1.0 2.8 0.0 0.6 128.4 36.7 3.1 2.5 0.2 0.0 17.8 12.4 5.6 5.0 0.2 28.8 0.0 0.3 25.2 50.3 0.7 96.0 4.2 14.0 0.4 2.7 0.2 0.0 1.0 3.4 0.0 1.5 0.4 0.3 0.0 38.4 0.4 65.6 4.6 ATP5F1A "ATP5A, ATP5A1, ATP5AL2, ATPM, hATP1, OMR, ORM" ENSG00000152234 "ATP synthase F1 subunit alpha" P25705 18 46080248-46104334 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 1760.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 784.3;Distal tubular cells: 1173.9;Extravillous trophoblasts: 463.0;Proximal tubular cells: 939.6;Syncytiotrophoblasts: 578.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013067, HPA040622, HPA044202" Enhanced Supported Mitochondria NA NA 8800000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "CAB013067: AB_221511, HPA040622: AB_2677048, HPA044202: AB_2678855" "unprognostic (3.08e-2)" "unprognostic (9.13e-2)" "unprognostic (1.84e-2)" "unprognostic (3.54e-1)" "unprognostic (6.36e-2)" "unprognostic (2.61e-1)" "unprognostic (1.89e-2)" "unprognostic (6.79e-2)" "unprognostic (8.31e-2)" "unprognostic (4.79e-2)" "unprognostic (7.30e-3)" "unprognostic (1.50e-2)" "prognostic favorable (1.22e-15)" "unprognostic (4.60e-3)" "unprognostic (2.06e-1)" "unprognostic (1.77e-1)" "unprognostic (4.87e-3)" 251.3 453.6 198.6 177.7 209.2 210.5 260.4 233.0 251.4 195.5 401.9 414.0 438.9 192.6 225.6 362.6 227.2 146.3 1498.3 207.7 246.0 730.4 441.6 175.1 223.7 234.6 237.8 211.1 299.9 868.5 277.4 201.7 226.0 211.4 419.8 465.4 307.4 265.9 1602.0 290.3 335.0 233.0 205.4 226.8 419.1 167.6 226.7 277.3 261.4 1760.3 337.6 244.9 224.7 209.6 355.2 353.0 459.6 434.3 546.0 601.8 508.6 399.5 562.4 601.0 522.8 532.7 271.9 833.2 238.9 487.4 322.3 641.7 801.1 614.1 556.4 373.0 450.3 551.7 413.3 667.2 357.1 1182.7 501.6 559.2 422.3 434.6 448.2 481.3 630.4 442.5 454.0 477.2 521.8 367.6 612.8 579.7 432.3 344.5 367.6 596.5 533.8 1131.4 816.2 849.7 465.7 434.7 293.3 361.5 506.9 428.6 466.3 679.3 370.4 328.7 282.7 174.9 354.9 542.5 501.5 533.0 328.1 698.0 358.7 119.1 573.9 162.7 353.6 511.8 455.9 492.3 422.7 388.4 959.5 392.9 503.3 421.7 55.9 414.5 485.1 468.3 527.4 1339.1 198.6 209.2 233.0 251.4 207.7 246.0 234.6 237.8 226.0 205.4 226.7 209.6 79.2 169.9 167.8 0.0 49.9 0.0 0.0 0.0 0.0 0.0 205.7 169.8 0.0 0.0 100.3 171.0 0.0 784.3 86.3 0.0 1173.9 358.3 0.0 125.3 163.3 73.0 0.0 0.0 0.0 269.7 463.0 97.8 0.0 119.3 89.6 198.7 0.0 0.0 409.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 87.5 0.0 0.0 179.9 0.0 0.0 0.0 0.0 199.1 0.0 0.0 24.0 0.0 0.0 939.6 95.5 0.0 0.0 0.0 87.1 0.0 0.0 0.0 0.0 578.2 54.6 319.2 0.0 0.0 ATP5PB ATP5F1 ENSG00000116459 "ATP synthase peripheral stalk-membrane subunit b" P24539 1 111448864-111462773 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 135.8;tongue: 131.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 346.5;Distal tubular cells: 461.8;Extravillous trophoblasts: 405.2;Hofbauer cells: 373.0;Proximal tubular cells: 434.6;Syncytiotrophoblasts: 347.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046067, HPA057347" Enhanced Supported Mitochondria "Intracellular and membrane" NA NA 170000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA046067: AB_10960850, HPA057347: AB_2683416" "unprognostic (4.18e-1)" "unprognostic (6.83e-2)" "unprognostic (1.10e-3)" "unprognostic (1.73e-2)" "unprognostic (3.56e-2)" "unprognostic (8.18e-2)" "unprognostic (8.52e-3)" "unprognostic (8.82e-2)" "unprognostic (3.67e-2)" "unprognostic (7.18e-3)" "unprognostic (3.29e-1)" "unprognostic (2.92e-1)" "prognostic favorable (3.26e-9)" "prognostic favorable (8.07e-4)" "unprognostic (1.60e-1)" "unprognostic (2.62e-1)" "unprognostic (1.93e-1)" 19.3 15.7 10.3 11.5 12.5 15.3 18.8 14.5 27.4 17.4 3.9 51.6 28.8 16.6 16.0 26.8 23.9 16.3 109.0 12.1 10.2 40.3 40.2 13.7 24.0 13.4 12.0 19.2 18.5 33.8 7.1 21.6 14.9 22.3 33.6 28.5 29.8 18.7 135.8 15.7 19.0 17.9 9.6 15.2 22.6 15.5 12.8 15.7 31.1 131.0 22.4 21.9 7.4 14.1 55.6 17.6 44.1 36.9 35.6 34.2 34.1 57.0 68.9 67.3 54.7 31.8 29.1 84.9 52.3 45.5 14.3 56.1 69.4 79.5 65.1 61.9 33.2 76.1 21.3 21.5 26.0 98.3 70.8 30.3 40.9 69.3 66.9 17.7 60.0 11.9 78.7 33.6 46.3 35.4 153.3 30.0 34.9 19.2 90.5 41.2 143.6 34.0 54.7 26.0 37.2 13.4 49.4 72.7 55.6 12.6 54.8 46.0 50.6 32.0 49.1 59.4 61.2 41.8 44.5 172.1 70.8 77.6 60.8 3.5 15.4 7.1 14.8 10.0 12.2 12.9 15.1 13.3 16.1 15.2 16.9 10.4 4.8 9.8 9.0 9.2 15.1 44.2 10.3 12.5 14.5 27.4 12.1 10.2 13.4 12.0 14.9 9.6 12.8 14.1 73.2 67.3 83.8 0.0 31.5 0.0 0.0 0.0 0.0 0.0 112.9 155.3 0.0 0.0 57.6 125.0 0.0 346.5 56.4 0.0 461.8 237.3 0.0 132.5 111.0 58.8 0.0 0.0 0.0 196.7 405.2 57.0 0.0 125.4 89.6 82.1 0.0 0.0 373.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 81.8 0.0 0.0 98.8 0.0 0.0 0.0 0.0 162.6 0.0 0.0 9.8 0.0 0.0 434.6 74.3 0.0 0.0 0.0 58.0 0.0 0.0 0.0 0.0 347.7 41.8 208.0 0.0 0.0 ATRN "DPPT-L, MGCA" ENSG00000088812 Attractin O75882 20 3471018-3651118 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 101.6;Inhibitory neurons: 101.1;Oligodendrocyte precursor cells: 89.5;Oligodendrocytes: 85.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008853 Approved Approved Cytosol "Secreted to blood" NA NA 27000000000 "Cluster 52: Eosinophils - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA008853: AB_1078248" "unprognostic (6.42e-2)" "unprognostic (1.10e-1)" "unprognostic (2.04e-1)" "unprognostic (2.02e-1)" "unprognostic (2.52e-1)" "unprognostic (5.27e-2)" "unprognostic (1.65e-1)" "unprognostic (3.99e-2)" "unprognostic (4.28e-1)" "unprognostic (3.40e-2)" "unprognostic (4.61e-2)" "unprognostic (1.59e-1)" "prognostic favorable (2.19e-6)" "unprognostic (3.71e-2)" "unprognostic (9.49e-2)" "unprognostic (2.77e-1)" "unprognostic (3.91e-2)" 12.8 19.1 10.5 10.3 12.2 8.6 17.2 9.3 13.2 16.5 8.9 11.8 55.8 11.8 15.6 10.4 11.7 13.9 19.1 13.4 12.2 23.9 62.8 14.4 7.5 8.0 8.7 14.0 20.2 40.1 8.7 22.6 9.0 12.8 12.3 24.2 13.9 13.2 11.6 14.9 33.4 14.9 11.3 13.8 24.0 16.6 10.8 7.8 32.3 14.2 9.6 15.7 9.1 15.8 40.8 37.6 21.9 18.4 37.9 61.5 28.1 26.6 37.5 27.4 23.1 16.3 27.1 0.0 17.5 37.4 33.8 55.6 15.0 58.1 36.4 4.5 12.8 12.7 10.0 35.1 22.8 27.2 8.3 33.1 46.0 29.0 27.8 34.3 36.0 8.7 20.2 19.2 27.0 11.7 11.1 10.4 14.7 13.2 22.3 9.2 50.9 30.8 24.8 28.5 12.9 20.2 26.7 48.9 36.3 21.3 26.2 25.5 44.7 29.0 17.0 30.8 26.6 13.4 20.1 0.1 17.9 17.9 29.6 3.6 3.2 2.0 2.3 2.8 1.0 1.4 1.2 1.4 2.8 1.7 2.0 1.7 0.0 1.5 3.1 2.6 1.8 1.0 10.5 12.2 9.3 13.2 13.4 12.2 8.0 8.7 9.0 11.3 10.8 15.8 11.1 16.0 10.4 70.2 5.8 6.4 4.3 14.1 6.8 22.5 9.9 8.8 12.6 20.0 10.3 11.0 37.5 7.4 8.0 6.5 1.9 8.2 7.1 9.9 15.1 11.1 9.6 7.4 101.6 14.6 8.4 12.7 20.4 11.8 7.0 39.3 17.9 50.9 10.4 37.0 101.1 10.7 4.1 14.2 6.7 5.4 12.5 11.5 7.2 64.6 10.1 11.8 5.2 89.5 85.7 10.0 14.3 7.9 11.4 7.0 34.6 7.3 10.2 20.1 32.9 14.3 10.9 21.3 21.1 8.5 7.2 5.1 5.8 21.0 12.6 5.2 ATRNL1 "ALP, FLJ45344, KIAA0534" ENSG00000107518 "Attractin like 1" Q5VV63 10 115093365-115948999 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 91.1" "Group enriched" "Detected in many" 13 "Excitatory neurons: 2134.6;Inhibitory neurons: 1473.4;Oligodendrocyte precursor cells: 1456.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "cerebral cortex: 91.1;white matter: 58.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 21.4;RH-30: 18.4;U-266/70: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038070 Approved Nucleoplasm,Mitochondria NA NA 160000000 "Cluster 10: Brain - Neuronal signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Mitochondria" "HPA038070: AB_10697237" "unprognostic (3.85e-2)" "unprognostic (1.89e-1)" "unprognostic (5.88e-2)" "unprognostic (3.20e-3)" "unprognostic (1.57e-2)" "unprognostic (3.33e-1)" "unprognostic (1.11e-1)" "unprognostic (1.88e-2)" "unprognostic (5.17e-2)" "unprognostic (4.06e-2)" "unprognostic (2.18e-2)" "unprognostic (2.50e-2)" "unprognostic (1.04e-3)" "unprognostic (3.10e-2)" "unprognostic (2.76e-2)" "unprognostic (1.88e-2)" "unprognostic (2.08e-3)" 0.7 10.7 3.8 0.2 9.5 0.0 1.0 0.0 91.1 0.9 0.0 2.4 0.3 6.2 0.3 0.5 1.0 0.2 1.8 18.3 0.0 2.8 1.5 0.1 0.4 0.0 0.2 9.7 1.3 2.1 5.8 1.9 1.0 3.1 0.2 6.3 1.0 3.8 2.8 0.2 0.8 5.8 0.0 0.3 0.4 12.6 0.0 0.4 1.0 0.0 0.4 0.6 1.0 58.7 0.0 0.6 6.3 21.4 0.0 0.0 0.0 0.1 0.6 3.9 4.6 0.2 0.2 0.0 1.5 0.5 5.1 0.0 1.6 0.0 4.0 0.1 4.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.1 6.4 0.0 11.3 0.0 5.3 10.4 0.2 9.9 0.0 9.1 0.0 0.1 7.5 18.4 11.4 3.9 0.0 3.6 10.5 0.0 0.1 0.4 4.3 1.8 0.0 0.0 0.0 2.7 0.1 3.3 14.2 0.0 4.6 0.1 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 9.5 0.0 91.1 18.3 0.0 0.0 0.2 1.0 0.0 0.0 58.7 0.0 0.0 0.0 55.8 0.8 0.6 0.1 0.8 0.6 35.4 2.1 0.5 2.5 0.0 0.1 0.0 2.1 0.1 0.2 0.2 0.0 0.7 45.6 0.8 1.5 1.5 0.0 0.0 2134.6 0.4 0.0 5.3 0.0 1.8 0.0 24.9 21.0 0.1 3.0 10.1 1473.4 0.0 0.0 1.9 0.4 47.8 1.5 0.3 0.0 128.4 0.0 4.3 0.0 1456.7 34.2 0.3 0.0 0.7 0.0 0.1 0.0 0.5 0.1 4.7 0.0 2.4 2.6 46.6 11.5 0.0 0.1 0.3 0.1 53.1 0.0 0.1 ATXN10 "E46L, FLJ37990, SCA10" ENSG00000130638 "Ataxin 10" Q9UBB4 22 45671798-45845307 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049531 Approved Supported "Plasma membrane,Cytosol" NA NA 40000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "HPA049531: AB_2680806" "unprognostic (5.73e-2)" "unprognostic (1.97e-1)" "unprognostic (1.27e-2)" "unprognostic (5.76e-2)" "unprognostic (3.01e-2)" "unprognostic (7.50e-2)" "unprognostic (1.19e-3)" "unprognostic (3.18e-1)" "unprognostic (2.15e-2)" "unprognostic (5.07e-2)" "unprognostic (8.38e-2)" "unprognostic (3.51e-1)" "unprognostic (1.23e-2)" "unprognostic (1.18e-1)" "unprognostic (6.22e-2)" "unprognostic (7.48e-2)" "unprognostic (6.98e-2)" 40.9 59.5 42.2 34.7 46.1 41.9 41.7 35.3 56.8 50.6 26.9 43.7 23.8 50.0 39.0 46.4 56.1 39.6 74.5 50.2 49.6 53.5 64.8 38.2 48.3 37.6 40.1 57.7 57.4 64.9 56.1 48.8 42.1 46.5 36.3 55.1 41.6 40.9 70.6 34.9 27.8 50.2 42.5 34.2 34.4 57.3 46.5 65.9 63.0 59.3 51.6 51.1 45.8 44.5 163.4 84.9 156.2 95.0 70.5 107.6 85.4 181.0 194.3 128.1 139.4 42.9 106.4 169.3 73.2 184.5 66.4 94.4 114.3 121.3 137.7 32.8 119.4 78.9 141.7 79.8 101.9 213.1 56.4 109.0 82.9 66.5 103.1 153.1 96.3 76.2 58.7 89.8 197.2 69.6 116.7 95.6 104.2 90.8 64.0 166.2 60.7 135.9 162.6 152.3 86.9 136.6 113.5 67.2 129.2 119.8 101.4 111.9 87.6 127.5 47.7 46.0 61.4 87.8 57.3 136.8 79.5 88.5 138.5 80.5 99.9 91.8 69.0 121.7 92.3 72.1 68.0 84.3 163.9 72.6 74.4 71.9 4.7 86.2 138.5 58.1 70.8 120.2 42.2 46.1 35.3 56.8 50.2 49.6 37.6 40.1 42.1 42.5 46.5 44.5 38.1 35.3 33.3 127.3 50.6 50.5 124.2 156.0 68.9 66.3 45.4 50.0 94.2 65.8 76.7 58.8 20.9 101.9 32.3 17.1 68.4 91.1 69.2 53.7 53.7 44.4 60.3 63.1 148.6 69.5 106.3 70.7 34.1 49.8 39.9 93.5 36.4 54.9 72.2 70.7 157.9 35.4 79.3 49.0 36.5 40.6 57.5 48.3 24.9 103.0 67.9 79.3 27.8 186.5 168.1 51.6 24.0 75.6 53.3 115.2 18.6 66.9 67.6 53.6 46.0 45.1 54.6 133.8 108.3 65.1 41.5 52.3 47.8 102.2 44.5 102.0 ATXN2L "A2D, A2lp" ENSG00000168488 "Ataxin 2 like" Q8WWM7 16 28823035-28837237 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041506, HPA043391, HPA071955" Approved Enhanced Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Cytosol "HPA041506: AB_2677521, HPA043391: AB_2678459, HPA071955: AB_2686478" "unprognostic (1.64e-2)" "unprognostic (1.72e-1)" "unprognostic (7.33e-3)" "unprognostic (1.03e-2)" "unprognostic (3.11e-1)" "unprognostic (6.63e-2)" "prognostic unfavorable (9.85e-4)" "unprognostic (5.59e-2)" "unprognostic (7.56e-2)" "unprognostic (1.02e-1)" "unprognostic (2.11e-1)" "unprognostic (2.83e-2)" "prognostic unfavorable (7.99e-7)" "unprognostic (1.79e-1)" "unprognostic (1.61e-2)" "unprognostic (7.22e-2)" "unprognostic (2.98e-1)" 67.8 78.2 80.2 51.6 86.2 82.9 65.3 89.9 116.8 83.3 72.7 75.6 43.8 71.3 20.9 81.9 77.8 29.2 68.8 82.2 82.2 85.7 96.1 85.9 62.7 83.2 80.4 81.3 96.8 33.7 116.4 39.0 83.4 80.6 27.0 56.5 70.1 27.9 63.8 76.9 86.3 33.4 75.5 117.0 82.6 178.9 83.5 52.5 83.0 23.7 46.9 75.5 77.7 86.0 77.8 97.6 99.0 112.1 59.9 61.5 116.1 76.3 73.7 82.1 91.3 124.1 90.1 178.6 95.4 54.4 128.6 110.2 93.9 76.9 90.5 140.9 83.3 119.5 124.3 127.4 107.5 135.9 161.2 78.8 90.1 116.4 166.1 72.4 73.2 174.4 158.9 219.9 68.4 109.9 166.1 228.0 100.6 46.9 67.2 216.4 68.5 125.6 48.9 79.6 102.8 81.9 44.6 83.5 95.8 62.3 91.3 141.0 88.2 101.2 83.6 65.8 106.2 311.9 238.1 159.4 76.3 128.1 119.6 0.4 2.1 1.4 1.6 1.9 1.6 4.3 1.9 2.0 1.6 2.9 1.8 2.3 2.4 1.9 1.6 5.6 1.7 1.1 80.2 86.2 89.9 116.8 82.2 82.2 83.2 80.4 83.4 75.5 83.5 86.0 30.2 28.9 33.3 26.1 48.2 36.6 25.1 20.2 66.0 31.6 29.8 26.3 2.1 21.5 19.8 20.2 45.9 23.0 39.1 19.8 1.9 17.8 71.7 37.7 34.9 27.8 24.6 23.1 37.3 20.2 21.9 20.8 31.6 53.1 25.9 23.4 27.1 14.7 24.8 26.9 37.5 23.4 14.2 29.3 33.3 25.7 21.5 36.5 8.8 24.4 26.4 10.0 33.0 18.6 31.5 32.2 19.4 19.9 65.1 33.0 19.7 4.8 18.8 48.9 13.1 28.9 22.1 83.9 28.3 46.3 31.1 34.3 48.4 24.5 23.4 27.4 AVPR1A AVPR1 ENSG00000166148 "Arginine vasopressin receptor 1A" P37288 12 63142759-63151201 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 56.6" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 24.1;Hepatocytes: 62.7;Sertoli cells: 78.9;Smooth muscle cells: 100.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "ASC diff: 5.6;Karpas-707: 13.1;U-266/84: 9.8" "Group enriched" "Detected in some" 5 "basal ganglia: 7.0;hypothalamus: 3.8" "Low region specificity" "Detected in all" NA NA "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (1.49e-1)" "unprognostic (2.82e-1)" "unprognostic (9.90e-3)" "unprognostic (2.90e-1)" "unprognostic (1.59e-1)" "unprognostic (1.43e-3)" "unprognostic (3.79e-2)" "unprognostic (2.60e-1)" "unprognostic (3.58e-6)" "unprognostic (1.45e-1)" "unprognostic (7.29e-2)" "unprognostic (1.55e-1)" "unprognostic (1.38e-3)" "unprognostic (4.65e-3)" "unprognostic (1.25e-1)" "unprognostic (4.77e-2)" "unprognostic (4.66e-4)" 17.2 56.6 0.4 1.4 0.2 0.0 9.0 0.0 0.3 9.1 1.4 1.7 0.7 10.9 1.1 3.0 4.8 6.1 2.0 0.3 0.5 4.6 20.9 0.5 1.2 0.5 0.2 1.3 2.3 2.2 0.5 0.3 0.2 2.3 1.2 1.4 1.1 4.2 2.0 1.8 0.9 12.2 0.1 0.8 1.7 0.6 0.8 1.4 10.4 3.5 0.6 2.5 2.6 0.2 0.1 0.2 0.6 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.2 0.0 0.3 0.3 0.5 0.5 0.2 0.2 0.1 0.8 0.2 14.1 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.6 0.3 0.2 0.3 3.4 1.5 0.0 5.5 0.0 0.1 0.0 0.0 0.0 0.0 0.4 3.1 24.1 4.5 0.0 2.7 0.1 0.0 0.5 2.7 0.5 1.6 0.0 0.2 0.7 62.7 0.2 0.0 1.0 0.0 0.0 1.3 0.3 0.0 2.8 1.4 0.0 0.0 0.0 7.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 78.9 2.9 100.9 0.2 0.2 0.0 0.3 0.1 0.6 2.1 0.0 0.3 AZGP1 "ZA2G, ZAG" ENSG00000160862 "Alpha-2-glycoprotein 1, zinc-binding" P25311 7 99966720-99976042 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 2809.6;salivary gland: 3847.3" "Cell type enhanced" "Detected in many" "Breast glandular cells: 1315.5;Breast myoepithelial cells: 704.8;Hepatocytes: 4270.8;Ionocytes: 901.3;Prostatic glandular cells: 1691.9;Urothelial cells: 674.2" "Group enriched" "Detected in many" 12 "breast cancer: 412.6;liver cancer: 273.6;prostate cancer: 469.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 56.6;OE19: 158.9;RPMI-8226: 130.4;T-47d: 41.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012582, HPA012876, CAB016087, CAB032276" Enhanced Approved Nucleoplasm,Vesicles "Secreted to blood" NA NA 55200000000 74000000000 "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" Vesicles Nucleoplasm "CAB016087: AB_667849, CAB032276: AB_2062580, HPA012582: AB_1845226, HPA012876: " "unprognostic (8.14e-2)" "unprognostic (1.50e-1)" "unprognostic (3.41e-1)" "unprognostic (5.42e-3)" "unprognostic (4.98e-2)" "unprognostic (5.74e-3)" "prognostic favorable (2.90e-4)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (2.19e-1)" "unprognostic (2.35e-2)" "unprognostic (1.79e-1)" "prognostic favorable (1.53e-4)" "unprognostic (2.18e-1)" "unprognostic (2.08e-2)" "unprognostic (9.80e-2)" "unprognostic (3.51e-3)" 128.6 3.9 17.1 2.7 28.8 0.4 1061.4 23.1 18.8 3.4 16.0 6.7 30.9 1.5 2.5 22.0 3.0 38.7 114.7 14.9 22.2 326.8 2809.6 14.8 0.4 20.2 23.3 6.0 752.1 0.1 1.3 0.5 27.1 1051.4 4.2 3.6 3847.3 40.2 1.7 206.8 28.6 0.3 14.0 1.4 315.2 25.9 21.4 0.8 1.9 2.3 1.5 5.8 7.5 24.5 0.2 0.0 0.0 0.0 11.3 0.0 5.5 0.0 0.0 0.0 0.0 0.1 4.0 14.2 0.7 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.1 0.3 0.1 56.6 4.9 1.5 0.1 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.3 29.9 0.0 0.0 0.0 5.1 0.2 158.9 0.0 0.0 1.7 130.4 0.0 0.0 0.0 2.0 1.0 25.4 13.0 0.0 41.8 0.0 0.0 0.5 0.1 1.8 0.9 1.9 0.8 0.4 0.0 0.5 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 28.8 23.1 18.8 14.9 22.2 20.2 23.3 27.1 14.0 21.4 24.5 9.9 22.4 276.8 0.0 14.7 4.2 422.1 25.3 0.0 0.0 1315.5 704.8 115.9 451.8 63.0 5.5 2.1 0.0 10.4 5.5 46.9 11.7 1.9 1.4 1.2 14.2 12.4 85.5 0.1 254.2 0.0 7.7 94.8 5.5 3.8 1.2 65.3 4270.8 0.0 0.0 0.1 13.1 901.3 93.1 0.7 4.2 0.9 14.8 62.2 1.0 2.0 23.7 0.0 7.5 7.3 221.5 6.4 0.0 0.3 1691.9 15.3 596.1 6.3 0.3 0.0 0.0 11.9 7.4 0.4 9.9 9.7 0.0 12.3 0.1 12.6 674.2 B3GNT9 MGC4655 ENSG00000237172 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9" Q6UX72 16 67148104-67150998 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 12.9;Leydig cells: 11.5;Peritubular cells: 13.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SiHa: 50.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052743, HPA062734" Approved Approved "Nucleoli fibrillar center,Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoli fibrillar center" "HPA052743: AB_2681934, HPA062734: AB_2684854" "unprognostic (2.56e-2)" "unprognostic (2.22e-1)" "unprognostic (2.34e-2)" "unprognostic (1.07e-1)" "unprognostic (6.58e-2)" "unprognostic (1.11e-1)" "unprognostic (1.32e-3)" "unprognostic (3.28e-2)" "unprognostic (3.01e-2)" "unprognostic (1.89e-1)" "unprognostic (1.96e-2)" "unprognostic (2.16e-2)" "unprognostic (1.82e-2)" "unprognostic (1.51e-2)" "unprognostic (1.15e-1)" "unprognostic (4.96e-3)" "unprognostic (7.56e-3)" 7.7 8.4 7.1 4.2 8.0 0.2 5.7 7.5 6.8 15.0 8.4 7.6 3.2 13.4 7.3 5.2 13.7 6.8 13.8 7.1 8.0 7.4 2.5 9.0 2.9 8.7 9.7 15.0 3.5 21.8 20.5 7.9 8.7 11.8 3.3 1.4 9.0 14.8 1.9 5.9 5.6 7.8 9.3 5.6 6.1 6.0 7.7 1.5 18.7 2.1 2.5 11.7 8.9 11.1 4.9 8.8 0.7 0.9 27.7 28.6 1.0 22.5 36.2 14.4 18.5 4.0 0.8 0.6 1.5 34.9 6.0 11.1 0.3 1.0 7.8 7.6 3.2 0.7 9.7 3.5 22.3 0.6 0.5 23.7 8.3 14.0 0.4 35.8 2.0 0.5 1.0 2.7 22.6 2.6 2.6 1.2 5.4 3.8 7.7 7.4 12.9 4.4 2.3 6.0 5.0 11.2 50.9 0.2 0.8 4.3 1.3 3.9 4.6 25.6 1.1 25.9 10.2 3.2 2.4 0.8 31.9 1.3 12.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 7.1 8.0 7.5 6.8 7.1 8.0 8.7 9.7 8.7 9.3 7.7 11.1 1.2 6.4 5.0 1.0 1.2 3.2 2.8 2.4 9.6 1.6 3.2 2.3 2.6 5.7 2.4 3.7 0.0 0.3 0.1 0.4 0.0 1.3 5.3 2.5 7.6 2.0 2.4 0.0 0.4 1.7 0.5 12.9 2.6 2.2 0.0 3.0 6.4 0.1 1.8 0.0 1.3 0.9 2.0 0.6 3.3 6.9 11.5 0.4 1.8 0.0 0.1 0.9 0.0 1.0 2.3 0.9 0.1 13.5 4.7 2.4 0.1 0.9 4.2 0.3 6.6 3.2 6.6 4.4 2.8 2.7 4.1 0.8 1.5 2.9 0.8 1.3 BAALC ENSG00000164929 "BAALC binder of MAP3K1 and KLF4" Q8WXS3 8 103140713-103230305 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 300.9;choroid plexus: 108.2" "Cell type enhanced" "Detected in many" "Adipocytes: 67.8;Astrocytes: 198.2;Excitatory neurons: 131.4;Inhibitory neurons: 62.3;Muller glia cells: 132.4;Oligodendrocyte precursor cells: 125.7" "Cancer enriched" "Detected in many" 8 "glioma: 139.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "NK-cell: 3.7" "Lineage enriched" "Detected in single" 28 "NK-cells: 3.7" "Cell line enhanced" "Detected in many" "AF22: 51.7;BJ hTERT+: 18.1;SCLC-21H: 27.9;SH-SY5Y: 20.5;U-87 MG: 75.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027132, HPA068307" Approved Supported Nucleoplasm,Cytosol No NA "Cluster 48: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol Nucleoplasm "HPA027132: AB_10600985, HPA068307: AB_2685971" "unprognostic (1.68e-1)" "unprognostic (9.17e-3)" "unprognostic (1.40e-2)" "unprognostic (4.62e-4)" "unprognostic (1.75e-2)" "unprognostic (2.84e-2)" "unprognostic (1.39e-1)" "unprognostic (7.87e-2)" "unprognostic (2.00e-1)" "unprognostic (4.99e-2)" "unprognostic (4.17e-2)" "unprognostic (2.18e-2)" "unprognostic (7.58e-2)" "unprognostic (2.51e-3)" "unprognostic (2.76e-2)" "unprognostic (1.70e-1)" "unprognostic (9.27e-3)" 9.3 15.6 196.7 2.1 209.2 3.4 7.0 182.2 226.6 1.6 108.2 3.1 0.9 1.7 0.4 0.7 3.8 1.6 3.1 201.1 206.8 4.3 2.9 7.3 1.4 240.0 237.4 3.3 2.1 0.4 25.9 5.3 219.5 1.1 1.6 19.4 1.0 0.9 2.0 2.0 2.7 1.8 229.2 14.5 2.4 1.3 300.9 0.6 4.5 1.4 0.8 2.5 1.4 205.3 0.5 3.0 51.7 0.5 0.5 14.9 0.0 2.6 18.1 0.1 0.2 0.5 0.1 0.2 0.5 10.1 0.2 0.8 0.9 0.1 0.1 0.1 3.1 0.5 0.8 0.1 1.2 0.0 1.1 3.0 2.9 0.6 0.0 2.7 0.4 0.1 0.0 0.4 0.1 0.4 0.0 0.2 1.3 0.4 1.0 0.2 0.3 1.2 0.0 0.1 27.9 20.5 0.6 0.0 0.1 4.5 0.2 0.3 3.0 16.0 1.0 0.4 1.0 0.0 0.2 0.2 75.7 0.3 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.2 196.7 209.2 182.2 226.6 201.1 206.8 240.0 237.4 219.5 229.2 300.9 205.3 67.8 0.0 1.8 198.2 0.3 5.5 0.7 4.5 0.6 2.1 2.0 1.1 0.8 17.2 5.9 0.0 0.0 0.1 2.1 0.3 7.9 32.0 2.9 15.6 2.3 33.4 17.8 6.1 131.4 25.6 0.1 1.6 0.0 34.0 0.0 0.0 23.6 0.8 0.9 0.0 62.3 3.4 22.4 1.3 6.2 8.7 1.5 2.1 14.2 18.7 4.6 132.4 2.1 125.7 46.1 4.1 1.2 0.0 0.8 0.8 0.1 0.1 21.7 3.3 0.0 2.1 8.1 0.1 0.1 0.3 4.0 0.0 1.3 0.3 0.1 1.1 BAAT BAT ENSG00000136881 "Bile acid-CoA:amino acid N-acyltransferase" Q14032 9 101354182-101385400 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Serine esterase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 41 "liver: 721.0" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 996.7" "Cancer enriched" "Detected in many" 42 "liver cancer: 181.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 3.4;CACO-2: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021251, HPA021330" Enhanced Uncertain Vesicles NA NA 520000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA021251: AB_1845247, HPA021330: AB_2670674" "unprognostic (2.53e-2)" "unprognostic (1.81e-1)" "unprognostic (9.97e-2)" "unprognostic (9.33e-2)" "unprognostic (7.75e-3)" "unprognostic (4.68e-2)" "prognostic favorable (4.97e-4)" "unprognostic (2.14e-2)" "unprognostic (6.19e-2)" "unprognostic (4.43e-4)" "unprognostic (3.65e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (4.24e-7)" "unprognostic (1.74e-1)" "unprognostic (2.12e-1)" "unprognostic (2.17e-2)" "unprognostic (1.75e-1)" 0.1 0.0 0.5 0.0 0.5 1.2 0.0 0.5 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 17.4 0.1 0.5 0.4 0.3 721.0 0.4 0.0 0.4 0.3 0.0 0.9 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.8 0.0 3.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.1 0.1 0.1 0.4 0.8 0.2 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.5 1.0 0.5 0.4 0.4 0.3 0.5 0.1 0.3 0.8 0.3 0.0 0.0 0.7 2.4 0.0 0.1 0.0 0.0 1.1 0.3 0.1 0.7 91.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.1 0.0 0.1 0.7 0.0 16.0 9.7 0.2 0.0 0.1 0.0 0.1 0.0 0.0 12.1 996.7 0.0 0.0 7.2 0.0 0.0 18.2 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.1 0.0 3.0 0.9 1.8 0.1 0.0 0.0 0.0 0.3 0.3 0.0 0.2 0.0 0.5 0.1 0.3 0.2 0.0 0.0 0.0 1.0 0.1 0.4 0.0 BAIAP3 "BAP3, KIAA0734" ENSG00000007516 "BAI1 associated protein 3" O94812 16 1333638-1349441 "Predicted intracellular proteins" "Exocytosis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "brain: 221.6;pituitary gland: 367.9" "Cell type enhanced" "Detected in many" "Astrocytes: 21.5;Endometrial ciliated cells: 23.5;Enteroendocrine cells: 50.3;Excitatory neurons: 19.2;Respiratory ciliated cells: 45.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "CAPAN-2: 20.2;MCF7: 6.2;RT4: 5.6" "Region enhanced" "Detected in many" "hypothalamus: 123.4" "Low region specificity" "Detected in all" "HPA015627, HPA015979" Uncertain Supported NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "HPA015627: AB_10603678, HPA015979: " "unprognostic (1.37e-2)" "unprognostic (3.93e-2)" "unprognostic (2.44e-2)" "unprognostic (3.92e-3)" "unprognostic (4.43e-2)" "unprognostic (1.10e-1)" "unprognostic (2.25e-1)" "unprognostic (1.06e-1)" "unprognostic (5.60e-2)" "unprognostic (6.75e-3)" "unprognostic (1.44e-1)" "unprognostic (2.02e-1)" "prognostic favorable (1.52e-5)" "unprognostic (5.26e-2)" "unprognostic (3.11e-1)" "unprognostic (7.12e-3)" "unprognostic (6.43e-2)" 3.2 19.3 87.5 1.1 86.9 0.9 5.1 2.3 74.9 5.0 11.5 4.0 3.9 1.2 1.9 2.2 31.2 0.5 4.0 60.7 221.6 12.5 8.1 6.1 1.3 59.8 108.9 0.8 8.0 3.6 367.9 1.8 58.8 9.7 0.8 0.7 4.8 2.4 2.7 2.1 13.5 0.1 37.5 6.8 6.0 20.5 181.6 0.3 1.6 1.1 0.7 2.6 2.0 26.4 0.1 2.3 4.0 1.3 0.4 0.0 1.0 0.2 0.1 0.2 0.0 3.6 20.2 0.3 2.7 0.0 0.1 0.1 0.0 0.2 0.0 0.2 1.3 0.1 0.4 1.4 0.3 0.0 2.7 0.0 0.0 0.2 0.1 0.2 0.1 0.3 0.7 0.0 0.0 6.2 0.0 0.8 2.3 1.0 3.4 0.6 0.0 4.0 2.3 5.6 0.5 0.2 0.0 1.8 0.1 1.1 4.3 0.3 0.3 0.0 2.2 0.5 0.0 1.5 0.5 0.1 0.1 0.4 0.1 0.0 0.0 0.1 0.3 0.0 0.1 1.6 0.1 0.5 0.0 0.1 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.1 87.5 86.9 2.3 74.9 60.7 221.6 59.8 108.9 58.8 37.5 181.6 26.4 5.6 0.0 0.0 21.5 7.7 0.5 3.3 2.4 1.8 1.6 2.5 1.9 1.3 0.0 4.9 5.5 0.0 0.2 1.9 2.8 0.0 0.7 4.0 23.5 0.9 2.3 50.3 2.7 19.2 0.2 0.3 0.6 4.1 3.7 0.0 2.0 2.9 4.7 0.1 0.0 13.2 3.2 8.2 0.0 0.4 2.0 0.6 0.2 1.8 1.0 0.1 0.8 0.0 1.5 2.3 0.2 0.8 0.0 4.0 2.9 4.0 0.6 45.7 0.6 6.6 0.9 2.7 2.6 1.8 1.6 0.4 1.1 1.7 0.1 2.9 1.9 BBIP1 "bA348N5.3, BBIP10, BBS18, NCRNA00081" ENSG00000214413 "BBSome interacting protein 1" A8MTZ0 10 110898730-110919201 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Bardet-Biedl syndrome, Ciliopathy, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 102.8" "Group enriched" "Detected in all" 4 "Early spermatids: 597.4;Late spermatids: 501.6;Spermatocytes: 399.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA055206 Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA055206: AB_2682737" "unprognostic (6.05e-2)" "unprognostic (1.61e-2)" "unprognostic (1.50e-1)" "unprognostic (6.25e-3)" "unprognostic (3.08e-2)" "unprognostic (1.43e-1)" "unprognostic (2.65e-2)" "unprognostic (6.26e-2)" "unprognostic (2.60e-2)" "unprognostic (3.00e-2)" "unprognostic (6.79e-3)" "unprognostic (3.90e-2)" "unprognostic (1.06e-1)" "unprognostic (2.16e-1)" "unprognostic (1.94e-1)" "unprognostic (1.81e-1)" "unprognostic (3.85e-2)" 17.6 24.9 25.8 16.0 29.9 10.1 15.5 29.8 41.2 18.7 23.7 16.6 10.3 16.6 25.3 10.5 20.0 12.3 20.4 25.3 26.9 29.8 23.5 14.1 16.4 28.8 26.9 19.5 13.8 19.0 25.6 13.8 29.0 19.2 10.7 50.1 10.5 16.2 15.5 7.3 12.4 16.0 27.2 16.7 14.3 102.8 26.6 17.8 21.7 10.1 16.6 16.2 12.9 37.2 22.1 28.9 33.0 34.0 41.4 51.0 9.8 27.2 56.4 30.9 42.7 14.4 26.9 13.3 19.2 44.9 31.4 21.5 23.9 30.1 47.5 26.9 28.6 22.0 28.3 18.9 54.4 18.9 37.0 31.8 27.1 42.4 75.7 68.9 50.3 23.7 16.5 49.8 37.0 13.9 23.8 27.0 14.0 15.3 18.1 10.5 59.7 18.8 48.6 13.9 24.9 39.6 20.7 9.1 45.4 21.1 10.4 16.9 36.5 22.3 27.2 27.3 38.2 27.9 26.0 19.9 63.4 33.5 17.6 25.5 11.2 47.6 9.7 15.0 11.5 8.2 14.5 12.0 9.5 7.2 17.6 14.9 53.6 7.8 13.0 8.4 18.8 7.4 25.8 29.9 29.8 41.2 25.3 26.9 28.8 26.9 29.0 27.2 26.6 37.2 32.3 25.6 10.0 25.8 24.2 11.2 36.2 41.4 17.1 32.3 13.9 16.3 18.5 22.8 24.3 22.0 31.3 19.3 21.4 9.5 105.7 35.8 597.4 60.4 27.1 26.4 16.9 18.3 58.8 34.5 25.6 27.7 14.3 24.4 16.5 21.0 25.4 22.1 20.0 45.4 52.6 18.4 50.8 22.4 15.8 501.6 46.6 22.4 23.2 14.0 27.1 52.4 26.8 27.6 67.5 36.0 12.0 33.8 32.2 21.6 13.5 69.4 75.7 63.8 52.6 46.0 32.7 399.5 36.5 12.5 11.9 12.3 27.2 21.0 10.0 29.7 BCL2L13 "BCL-RAMBO, MIL1" ENSG00000099968 "BCL2 like 13" Q9BXK5 22 17628855-17730855 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 59.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 180.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002052, HPA030994, HPA050377" Uncertain Enhanced Mitochondria NA NA 100000 "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 56: Bipolar cells - Visual perception" Mitochondria "CAB002052: AB_563431, HPA030994: AB_10795024, HPA050377: AB_2681107" "unprognostic (1.59e-1)" "unprognostic (8.17e-2)" "unprognostic (2.18e-3)" "unprognostic (1.86e-1)" "unprognostic (6.27e-2)" "unprognostic (2.69e-2)" "unprognostic (3.38e-1)" "unprognostic (4.97e-2)" "unprognostic (5.04e-2)" "unprognostic (9.46e-2)" "unprognostic (1.45e-2)" "unprognostic (8.21e-2)" "prognostic favorable (1.96e-8)" "unprognostic (3.20e-1)" "unprognostic (1.07e-1)" "unprognostic (4.27e-1)" "unprognostic (2.81e-1)" 13.4 13.3 8.7 5.7 11.6 10.8 11.5 8.4 12.8 7.7 1.4 10.0 6.0 7.9 8.8 12.3 7.4 6.8 19.7 9.4 9.9 14.0 16.4 8.4 7.6 11.6 13.7 7.5 11.8 14.8 7.8 9.2 12.1 8.2 10.3 43.8 10.0 6.8 59.6 14.1 7.8 7.6 9.2 6.4 9.5 10.7 9.7 9.2 9.6 40.5 8.7 10.3 8.7 9.4 16.2 6.1 10.6 11.1 19.6 18.8 17.2 11.4 21.3 17.1 19.8 8.3 11.7 14.6 7.5 15.4 13.9 21.3 12.6 18.4 20.9 12.2 12.3 14.5 7.5 6.1 22.3 21.3 10.0 14.5 21.1 14.0 40.1 24.2 14.7 11.3 34.5 15.2 18.9 11.6 11.7 8.9 10.7 26.8 9.7 10.9 20.7 5.3 20.1 12.4 15.6 11.5 16.4 15.6 31.0 38.0 11.9 18.0 17.2 9.9 5.0 15.3 10.5 11.9 10.5 14.7 14.9 16.1 16.4 5.1 9.5 2.3 2.3 8.0 2.8 3.1 3.1 2.7 5.4 3.2 2.8 2.3 3.6 6.5 6.4 2.9 4.5 4.7 8.7 11.6 8.4 12.8 9.4 9.9 11.6 13.7 12.1 9.2 9.7 9.4 18.7 22.4 16.7 32.3 21.5 24.6 33.6 22.7 30.1 180.5 21.8 22.4 42.7 12.8 25.3 18.4 12.5 48.5 19.7 31.7 52.8 29.1 34.8 17.7 16.0 17.5 23.4 19.8 41.9 31.6 35.0 20.0 13.3 23.5 8.8 19.7 15.7 36.0 26.0 48.8 38.1 25.4 18.3 30.8 19.8 15.5 14.0 26.3 16.0 27.2 54.7 57.9 12.3 27.6 45.4 36.4 17.8 15.4 15.4 40.3 32.6 44.4 19.6 35.2 0.0 21.3 15.6 33.1 22.6 32.1 27.1 95.9 19.3 22.9 24.0 43.1 BEND4 "CCDC4, FLJ35632, FLJ43965" ENSG00000188848 "BEN domain containing 4" Q6ZU67 4 42110853-42152878 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.6;prostate: 3.3;testis: 9.4" "Cell type enhanced" "Detected in some" "B-cells: 8.1;Inhibitory neurons: 6.2;Muller glia cells: 10.7;Spermatogonia: 38.3" "Group enriched" "Detected in some" 43 "prostate cancer: 6.3;testis cancer: 5.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 33.2;HEK 293: 7.9;HEL: 21.1;MOLT-4: 13.1;SuSa: 15.4;U-698: 13.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036850 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 36: HEL - Hemostasis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA036850: AB_10600787" "unprognostic (3.62e-4)" "unprognostic (3.82e-1)" "unprognostic (4.82e-2)" "unprognostic (5.96e-3)" "unprognostic (2.97e-3)" "unprognostic (1.10e-1)" "unprognostic (3.81e-2)" "unprognostic (4.00e-1)" "unprognostic (2.97e-1)" "unprognostic (5.58e-2)" "unprognostic (6.71e-3)" "unprognostic (1.68e-1)" "unprognostic (1.54e-5)" "unprognostic (3.48e-1)" "unprognostic (1.49e-1)" "unprognostic (4.58e-3)" "unprognostic (4.24e-1)" 0.0 0.0 0.7 1.1 0.7 0.8 0.0 0.0 1.3 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.0 1.3 1.1 0.0 0.1 0.2 2.1 1.2 3.6 0.1 0.0 0.0 1.0 0.3 2.8 3.3 0.2 1.1 0.0 0.0 0.0 0.0 1.2 0.1 0.1 1.2 0.2 9.4 0.7 1.1 0.0 0.0 1.6 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.6 0.0 33.2 0.0 0.0 0.0 7.9 21.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.4 0.0 7.0 0.0 0.1 0.0 0.0 13.1 0.0 6.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 4.7 0.8 0.0 0.0 0.0 15.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.2 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.7 0.0 1.3 1.3 1.1 1.2 3.6 2.8 0.1 0.7 0.4 0.4 0.0 0.0 0.0 8.1 0.0 0.1 0.0 0.0 1.2 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.6 0.0 3.4 4.4 0.0 0.0 0.3 0.0 0.0 0.0 4.8 2.5 0.0 0.0 3.3 6.2 0.0 0.0 0.0 0.0 1.5 0.0 0.3 0.0 0.0 0.1 10.7 0.0 3.5 0.2 0.0 0.0 0.0 3.9 1.7 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.6 38.3 0.0 0.0 0.0 1.5 2.2 0.0 0.0 BEND5 "C1orf165, FLJ11588" ENSG00000162373 "BEN domain containing 5" Q7L4P6 1 48727519-48776969 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 54.8;Proximal tubular cells: 30.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 6.5;naive B-cell: 8.0" "Lineage enriched" "Detected in many" 5 "B-cells: 8.0" "Cell line enhanced" "Detected in some" "AF22: 3.4;HDLM-2: 11.7;JURKAT: 4.5;MOLT-4: 4.8;REH: 6.5;SH-SY5Y: 2.9" "Low region specificity" "Detected in many" "HPA054347, HPA058007" Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nuclear speckles" Cytosol "HPA054347: AB_2682456, HPA058007: AB_2683577" "prognostic favorable (2.50e-5)" "unprognostic (1.36e-2)" "unprognostic (7.19e-3)" "unprognostic (1.16e-1)" "unprognostic (1.11e-1)" "unprognostic (1.65e-2)" "unprognostic (4.42e-2)" "prognostic favorable (1.29e-4)" "unprognostic (1.41e-1)" "unprognostic (6.02e-2)" "prognostic favorable (1.29e-4)" "unprognostic (1.32e-2)" "unprognostic (4.28e-2)" "unprognostic (2.37e-3)" "unprognostic (3.35e-2)" "unprognostic (9.68e-2)" "prognostic favorable (8.30e-6)" 1.7 1.9 5.1 0.7 5.1 1.0 1.8 4.1 7.4 2.8 4.1 3.4 0.4 2.0 1.5 0.6 2.5 2.0 1.6 5.1 4.3 3.4 0.1 0.9 2.1 6.3 5.0 4.4 1.7 1.8 3.4 0.3 6.4 1.5 0.4 3.7 1.0 1.2 2.6 0.8 1.6 0.7 4.1 2.7 1.7 1.0 4.8 4.8 1.8 1.7 1.4 2.2 1.7 5.3 0.0 0.0 3.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.1 0.0 4.8 0.2 2.6 0.0 0.0 6.5 1.1 0.0 0.0 1.2 1.1 2.9 0.0 0.0 0.2 1.2 0.0 0.3 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.2 1.7 8.0 1.6 1.0 0.2 1.2 0.0 1.7 0.0 0.4 5.1 5.1 4.1 7.4 5.1 4.3 6.3 5.0 6.4 4.1 4.8 5.3 8.7 6.4 3.1 0.0 17.2 1.9 4.6 4.6 1.8 13.3 4.0 16.9 8.6 8.6 6.1 5.5 16.7 0.3 0.6 0.5 54.8 6.4 8.9 2.7 1.9 6.9 12.1 0.8 0.0 1.8 0.5 8.4 2.6 1.3 1.3 10.2 4.6 0.2 0.3 8.4 0.0 0.8 2.0 0.6 4.4 7.1 13.1 1.5 3.6 0.0 0.5 22.7 0.0 0.0 0.0 2.6 4.5 21.4 7.6 1.1 0.2 30.2 6.4 17.8 6.6 6.8 5.6 3.7 9.1 0.3 2.3 0.1 2.8 11.4 1.6 1.9 BMPR1B "ALK6, CDw293" ENSG00000138696 "Bone morphogenetic protein receptor type 1B" O00238 4 94757955-95158448 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Chondrogenesis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.1;cervix: 24.7;prostate: 22.4" "Cell type enriched" "Detected in many" 7 "Astrocytes: 480.6" "Cancer enhanced" "Detected in many" "breast cancer: 32.4;prostate cancer: 24.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 22.0;MCF7: 11.1;SH-SY5Y: 18.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (2.25e-1)" "unprognostic (1.80e-2)" "unprognostic (1.40e-3)" "prognostic favorable (2.84e-4)" "unprognostic (1.57e-1)" "unprognostic (4.22e-2)" "unprognostic (1.92e-1)" "unprognostic (2.86e-2)" "unprognostic (2.95e-2)" "unprognostic (1.01e-1)" "unprognostic (3.97e-2)" "unprognostic (3.93e-1)" "unprognostic (1.62e-3)" "unprognostic (7.89e-4)" "unprognostic (6.22e-2)" "unprognostic (3.81e-3)" "unprognostic (2.63e-2)" 0.7 4.6 13.4 0.3 15.4 0.1 1.0 13.5 15.0 24.7 2.1 0.9 0.1 4.4 2.4 0.2 12.5 2.6 0.8 12.5 16.0 7.8 0.8 1.7 0.0 19.3 20.1 6.2 1.1 0.1 1.9 0.7 17.5 22.4 0.2 8.1 1.0 14.2 3.0 0.8 0.1 0.6 15.3 0.9 2.4 3.7 15.6 6.4 0.5 1.1 0.0 0.2 0.5 12.1 0.0 22.0 5.6 0.0 2.3 4.8 0.2 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.2 1.0 0.0 1.3 3.6 8.4 0.1 0.0 4.9 0.0 1.4 0.0 0.6 0.5 0.1 2.7 9.0 2.8 6.2 0.4 0.1 0.0 0.0 0.0 7.1 11.1 0.6 0.1 2.1 0.1 3.2 0.2 3.4 0.1 4.3 0.1 0.2 18.8 0.3 3.2 3.2 0.8 1.7 0.0 0.0 4.0 3.8 0.2 4.3 0.0 0.0 0.0 1.5 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.0 13.4 15.4 13.5 15.0 12.5 16.0 19.3 20.1 17.5 15.3 15.6 12.1 0.0 6.4 0.0 480.6 0.0 2.7 1.3 13.1 1.2 0.4 3.8 1.0 3.4 2.8 33.4 60.7 0.0 0.0 0.0 0.0 1.9 3.0 1.4 28.5 1.4 1.1 18.4 0.0 51.0 0.4 0.3 1.5 0.0 20.8 0.0 38.6 2.9 0.0 0.1 0.0 2.5 0.0 8.2 0.0 1.2 1.4 3.1 0.4 28.4 22.5 0.0 38.5 0.0 10.1 2.8 0.7 0.0 3.8 0.0 28.5 0.0 0.2 15.7 1.6 0.0 1.7 2.9 1.2 10.6 0.4 2.3 0.0 0.5 4.4 0.0 1.6 BNC1 "BNC, HsT19447" ENSG00000169594 "Basonuclin 1" Q01954 15 83255903-83284714 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" DNA-binding "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 15.0;esophagus: 12.5;testis: 30.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 88.6;Early spermatids: 45.5;Late spermatids: 103.4;Suprabasal keratinocytes: 58.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 25.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 51.1;HBEC3-KT: 116.6;hTCEpi: 128.1;hTERT-HME1: 123.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA063183, HPA066947, HPA077428" Enhanced Nucleoplasm NA NA "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA063183: AB_2684957, HPA066947: AB_2685752, HPA077428: AB_2732345" "unprognostic (1.86e-3)" "unprognostic (1.08e-1)" "unprognostic (7.89e-3)" "unprognostic (5.55e-2)" "unprognostic (4.06e-2)" "unprognostic (2.47e-2)" "unprognostic (2.45e-2)" "unprognostic (7.91e-2)" "unprognostic (8.89e-4)" "unprognostic (6.94e-2)" "unprognostic (4.13e-1)" "unprognostic (3.85e-3)" "unprognostic (8.46e-3)" "unprognostic (2.20e-1)" "unprognostic (2.95e-3)" "unprognostic (1.01e-2)" 15.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 3.1 0.0 0.1 0.0 0.0 8.1 12.5 0.9 0.1 1.4 0.2 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.7 0.0 1.0 0.0 1.8 0.0 0.2 0.0 0.1 2.0 0.2 0.0 9.3 0.0 0.0 0.0 0.0 0.1 30.8 0.3 4.2 0.1 0.3 2.1 0.3 6.5 0.4 25.9 0.1 0.0 0.0 4.2 6.4 0.0 2.0 0.3 21.9 30.3 0.0 0.5 0.0 1.0 13.8 0.0 51.1 2.7 116.6 39.3 0.0 0.2 0.0 0.0 0.0 32.6 0.0 0.0 5.6 128.1 19.6 123.8 4.5 21.7 0.0 0.0 0.0 16.6 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 4.6 0.0 0.0 0.0 11.6 0.0 0.0 14.2 0.0 0.0 40.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.1 0.0 0.0 0.0 0.0 88.6 14.8 15.5 14.8 0.0 0.0 0.1 0.4 1.5 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 45.5 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 6.9 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 5.5 103.4 0.6 0.1 8.8 1.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.7 0.0 1.2 0.0 0.1 1.7 0.0 0.0 2.7 0.6 22.2 6.5 21.7 58.4 0.0 0.0 0.0 0.0 4.8 BPI BPIFD1 ENSG00000101425 "Bactericidal permeability increasing protein" P17213 20 38304150-38337505 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 88 "bone marrow: 1503.7" "Group enriched" "Detected in some" 8 "Early spermatids: 201.8;Late spermatids: 220.6;Proximal tubular cells: 99.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "classical monocyte: 14.5;neutrophil: 7.1" "Group enriched" "Detected in many" 17 "granulocytes: 7.1;monocytes: 14.5" "Cell line enhanced" "Detected in single" "HL-60: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA061284 Enhanced "Secreted to blood" NA NA 7290000 78000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA061284: AB_2684465" "unprognostic (9.30e-4)" "unprognostic (5.49e-2)" "unprognostic (1.97e-1)" "unprognostic (2.26e-1)" "unprognostic (1.44e-1)" "unprognostic (1.56e-1)" "unprognostic (4.50e-2)" "unprognostic (1.98e-1)" "unprognostic (3.07e-2)" "unprognostic (1.14e-1)" "unprognostic (2.60e-2)" "unprognostic (1.50e-1)" "unprognostic (8.83e-6)" "unprognostic (2.66e-4)" "unprognostic (9.29e-2)" "unprognostic (2.32e-2)" "unprognostic (9.47e-3)" 0.5 0.2 0.1 0.1 0.2 1503.7 0.6 0.1 0.4 2.6 0.2 0.2 0.0 0.7 1.0 0.1 0.4 0.5 0.5 0.1 0.2 3.4 0.8 3.7 0.3 0.2 0.2 1.7 0.0 0.0 0.6 0.5 0.2 0.4 0.0 0.0 1.4 1.2 0.1 1.8 0.1 0.2 0.2 13.0 0.1 17.1 0.2 3.7 0.2 0.2 0.2 0.2 0.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 14.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 7.1 0.0 0.6 0.0 0.0 9.8 0.1 0.2 0.1 0.4 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.1 0.0 0.0 1.3 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.3 0.3 0.4 0.0 0.4 3.7 0.0 0.0 0.0 0.0 9.8 0.0 201.8 0.2 0.0 0.5 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.7 20.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 220.6 17.7 1.3 1.8 0.0 7.1 0.0 1.0 0.0 0.0 0.0 0.0 18.4 0.0 0.0 0.0 99.7 0.3 0.0 0.0 0.2 0.4 2.1 1.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 BRD9 FLJ13441 ENSG00000028310 "Bromodomain containing 9" Q9H8M2 5 850291-892801 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 110.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021465, HPA023197" Uncertain Enhanced Nucleoplasm NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 70: Brain - Nervous system development" "Cluster 44: HDLM-2 - Immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA021465: AB_1845441, HPA023197: AB_2671106" "unprognostic (3.10e-2)" "unprognostic (1.76e-1)" "unprognostic (1.45e-3)" "unprognostic (4.61e-2)" "unprognostic (5.89e-2)" "unprognostic (2.59e-2)" "prognostic unfavorable (5.88e-7)" "unprognostic (6.28e-2)" "unprognostic (7.53e-3)" "unprognostic (3.84e-2)" "unprognostic (8.82e-2)" "unprognostic (2.28e-2)" "prognostic unfavorable (2.37e-6)" "unprognostic (6.64e-2)" "unprognostic (1.07e-1)" "unprognostic (6.62e-3)" "unprognostic (1.02e-2)" 7.7 7.4 14.3 9.1 14.2 8.1 8.5 13.0 15.0 6.9 12.6 7.3 6.8 8.6 7.3 6.6 7.4 5.9 10.5 13.2 12.7 5.8 5.5 7.8 10.0 15.0 14.1 8.8 8.7 9.0 4.5 6.9 13.5 6.6 7.0 3.6 8.8 8.2 16.9 6.8 7.6 7.9 13.5 8.0 7.9 7.5 15.1 13.2 8.0 9.9 8.5 8.6 6.0 14.7 14.4 14.2 27.5 28.6 11.7 23.7 32.5 28.2 19.4 29.7 23.5 26.6 19.5 17.9 46.0 30.4 33.3 14.1 20.4 27.7 27.5 110.2 17.0 22.2 37.0 17.9 23.7 34.0 20.3 17.7 9.9 20.8 19.0 22.1 29.6 34.2 29.5 12.8 25.4 22.9 40.0 32.1 18.5 15.0 22.4 26.9 16.4 16.5 17.2 21.5 16.8 29.7 56.3 19.1 13.4 14.9 17.1 43.1 28.7 24.2 18.8 12.4 29.3 23.3 10.0 32.5 22.7 35.5 32.3 7.0 3.3 3.7 3.0 1.5 4.0 4.9 4.2 4.5 3.0 6.0 3.8 3.2 2.0 4.2 2.9 3.1 5.2 1.4 14.3 14.2 13.0 15.0 13.2 12.7 15.0 14.1 13.5 13.5 15.1 14.7 36.8 19.2 14.4 13.1 32.1 25.4 18.2 12.5 39.3 70.2 23.5 21.7 25.2 25.8 13.8 23.9 45.9 17.1 39.5 33.9 23.5 23.4 93.5 46.7 80.7 25.0 16.3 21.0 9.3 20.0 30.3 24.0 42.8 52.7 19.0 40.9 27.8 22.2 21.0 101.0 8.2 33.9 4.1 25.4 14.9 56.8 22.7 25.3 14.2 6.5 31.3 29.1 42.2 9.0 11.8 31.1 27.4 19.5 44.8 20.6 21.3 18.7 7.7 87.8 26.3 28.5 25.0 49.2 68.2 32.0 20.3 19.7 47.8 27.1 27.6 16.5 BRINP1 "DBC1, DBCCR1, FAM5A" ENSG00000078725 "BMP/retinoic acid inducible neural specific 1" O60477 9 119153458-119369435 "Predicted intracellular proteins, Transporters" "Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 43.5" "Group enriched" "Detected in some" 8 "Astrocytes: 178.9;Excitatory neurons: 285.7;Inhibitory neurons: 163.4;Oligodendrocyte precursor cells: 204.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 8.6;NTERA-2: 17.0;SCLC-21H: 7.4;SH-SY5Y: 3.2;SuSa: 6.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038828 Approved Uncertain Microtubules "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Microtubules "HPA038828: AB_10670909" "unprognostic (8.60e-5)" "unprognostic (2.31e-2)" "unprognostic (1.24e-1)" "unprognostic (5.09e-5)" "unprognostic (1.12e-1)" "unprognostic (1.14e-2)" "unprognostic (1.37e-1)" "unprognostic (2.98e-1)" "unprognostic (1.76e-1)" "unprognostic (1.02e-1)" "unprognostic (2.28e-4)" "unprognostic (1.51e-2)" "unprognostic (5.06e-3)" "unprognostic (1.39e-3)" "unprognostic (1.56e-1)" "unprognostic (7.59e-2)" "unprognostic (1.41e-1)" 0.1 3.8 28.8 0.0 23.3 0.0 2.4 20.5 43.5 0.5 0.0 0.2 0.2 0.7 4.9 0.6 0.0 1.4 1.8 35.7 17.8 1.7 0.6 1.9 0.0 9.6 20.6 0.1 0.0 0.0 1.6 0.0 16.8 1.5 0.1 5.3 0.7 5.2 0.3 0.1 0.6 0.1 16.0 0.3 0.2 0.5 27.7 0.8 0.3 0.1 0.0 0.3 0.2 18.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 17.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 7.4 3.2 0.0 0.0 0.0 6.0 0.6 0.0 0.0 1.1 1.8 0.0 0.8 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.8 23.3 20.5 43.5 35.7 17.8 9.6 20.6 16.8 16.0 27.7 18.8 0.1 0.0 0.0 178.9 0.0 0.0 0.5 0.5 0.0 8.7 8.1 4.2 0.9 0.0 0.1 0.0 25.0 0.1 0.0 0.3 0.0 0.0 2.1 0.5 15.9 0.5 2.4 0.0 285.7 0.0 0.0 0.4 0.0 0.4 0.0 0.2 2.9 0.0 0.3 1.7 163.4 0.0 0.0 0.3 0.0 1.0 0.0 0.3 0.0 8.4 0.0 1.6 0.0 204.6 4.9 0.1 0.0 0.4 0.0 0.4 0.0 23.9 0.0 2.6 0.0 0.0 0.4 1.0 1.7 0.0 0.0 0.0 0.2 0.1 0.0 0.3 BTBD3 "dJ742J24.1, KIAA0952" ENSG00000132640 "BTB domain containing 3" Q9Y2F9 20 11890723-11926609 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 80.9" "Cell type enhanced" "Detected in all" "Endometrial stromal cells: 223.0;Oligodendrocytes: 254.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 241.1;HeLa: 186.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041424, HPA042048" Uncertain Supported Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA041424: AB_10794667, HPA042048: AB_10796469" "unprognostic (3.93e-2)" "unprognostic (2.25e-1)" "unprognostic (1.32e-1)" "unprognostic (3.56e-3)" "unprognostic (4.24e-3)" "unprognostic (8.45e-2)" "prognostic unfavorable (2.51e-5)" "prognostic unfavorable (6.94e-4)" "unprognostic (4.87e-2)" "unprognostic (2.95e-1)" "unprognostic (1.07e-2)" "unprognostic (7.05e-2)" "unprognostic (6.66e-2)" "unprognostic (7.68e-3)" "unprognostic (1.67e-1)" "unprognostic (6.29e-2)" "unprognostic (1.37e-2)" 11.2 22.1 20.6 7.1 34.2 12.2 12.7 66.2 80.9 16.9 12.3 21.4 10.7 18.7 7.9 9.9 15.4 13.4 13.9 79.6 30.9 11.6 7.7 12.2 4.1 30.5 24.7 11.5 13.7 11.2 8.9 42.0 23.1 15.1 17.5 42.5 13.9 10.6 15.9 20.7 10.9 16.5 24.2 7.8 27.3 14.7 23.7 10.8 11.5 13.2 3.1 18.4 10.1 64.7 7.0 19.5 52.1 241.1 10.6 11.3 14.0 21.9 14.0 24.3 15.5 11.2 10.7 2.0 18.1 31.7 9.6 18.1 27.2 15.4 39.1 0.1 24.1 7.1 186.9 23.9 11.1 11.6 4.2 20.2 18.8 21.8 17.5 13.4 13.8 12.0 12.7 18.8 24.3 5.1 14.0 10.7 25.0 29.0 5.5 18.4 10.4 7.0 22.2 34.0 22.7 40.0 60.8 24.6 53.3 27.9 14.4 11.5 10.7 13.2 33.6 12.4 24.6 6.9 9.9 0.3 8.6 3.2 87.6 0.0 1.2 0.1 0.0 1.7 0.0 0.0 0.0 0.0 1.4 0.1 0.3 0.0 0.3 0.7 3.5 1.0 0.0 0.6 20.6 34.2 66.2 80.9 79.6 30.9 30.5 24.7 23.1 24.2 23.7 64.7 17.4 16.0 8.4 24.5 2.8 16.6 10.8 8.0 18.8 15.3 15.2 11.9 16.5 10.0 8.3 5.5 79.2 23.3 1.0 41.0 3.9 9.8 8.3 51.3 223.0 25.0 20.9 4.6 46.9 8.3 4.0 15.6 28.5 55.8 2.5 9.4 33.5 8.5 8.5 65.6 38.0 9.4 10.2 4.8 13.4 13.6 16.4 6.5 14.2 39.4 3.2 17.7 1.0 61.9 254.9 9.7 25.9 8.6 2.7 13.2 11.4 6.6 24.1 56.9 6.6 19.9 18.6 10.0 16.1 11.7 17.2 21.8 1.8 42.0 13.3 11.3 BVES "HBVES, POP1, POPDC1" ENSG00000112276 "Blood vessel epicardial substance" Q8NE79 6 105096822-105137157 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion" "Developmental protein" "Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 27.8;skeletal muscle: 43.9;tongue: 29.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 34.2;Early spermatids: 36.1;Late spermatids: 55.3;Oligodendrocytes: 17.8;Spermatocytes: 24.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 29.7;WM-115: 30.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA014788, HPA018176" Enhanced Supported "Plasma membrane,Cell Junctions" Yes NA "Cluster 17: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cell Junctions" "HPA014788: AB_1845504, HPA018176: AB_1845503" "unprognostic (2.91e-1)" "unprognostic (2.45e-1)" "unprognostic (2.79e-2)" "unprognostic (1.73e-2)" "unprognostic (5.46e-2)" "unprognostic (3.66e-2)" "unprognostic (5.21e-2)" "unprognostic (2.22e-2)" "unprognostic (8.37e-2)" "unprognostic (4.49e-2)" "unprognostic (2.29e-2)" "unprognostic (8.92e-2)" "unprognostic (5.84e-3)" "unprognostic (3.77e-2)" "unprognostic (1.78e-1)" "unprognostic (2.02e-2)" "unprognostic (3.24e-4)" 2.9 0.7 2.6 2.3 7.1 0.2 1.5 5.8 3.6 2.5 4.6 14.9 1.4 5.8 1.7 5.3 2.8 1.8 27.8 2.7 4.3 1.6 0.3 1.9 0.6 7.3 5.6 1.0 0.6 0.7 2.4 3.5 7.4 5.2 3.3 0.2 1.4 10.0 43.9 0.7 3.0 17.7 5.2 0.3 6.9 11.5 5.2 0.2 1.3 29.3 0.4 9.3 2.2 10.8 1.3 2.0 7.6 1.3 10.9 14.9 3.3 5.8 4.1 8.8 11.6 0.5 0.0 0.0 0.0 10.9 14.7 0.1 3.3 2.0 8.1 0.0 2.8 0.0 1.0 0.3 2.4 0.0 0.6 8.7 6.9 13.6 1.1 6.6 4.0 3.3 0.1 19.3 19.7 0.1 0.2 1.0 1.6 0.0 0.0 5.7 29.7 0.0 0.0 0.0 9.9 17.1 3.7 0.1 7.7 5.5 0.0 20.0 8.9 14.0 0.0 0.0 15.3 1.8 0.8 0.0 8.3 0.0 30.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 2.6 7.1 5.8 3.6 2.7 4.3 7.3 5.6 7.4 5.2 5.2 10.8 2.1 0.0 0.0 1.6 0.0 0.3 0.4 0.1 0.6 0.0 0.4 1.0 34.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 36.1 1.9 4.4 3.1 0.0 0.0 3.3 0.0 0.2 2.6 0.0 6.0 0.0 0.9 2.2 0.1 2.3 0.0 0.6 0.0 0.0 0.0 1.9 55.3 1.2 0.5 0.0 3.7 1.0 0.0 0.0 5.0 17.8 0.1 0.0 3.4 0.0 0.5 0.1 0.1 0.1 0.0 13.1 11.8 4.4 24.4 5.4 0.1 0.9 0.1 0.2 1.3 0.0 0.3 C10orf67 "bA215C7.4, C10orf115, LINC01552, MGC46732" ENSG00000179133 "Chromosome 10 open reading frame 67" Q8IYJ2 10 23202696-23344845 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 5.1;fallopian tube: 4.8;testis: 12.4" "Group enriched" "Detected in some" 5 "Alveolar cells type 1: 38.5;Early spermatids: 40.2;Endometrial ciliated cells: 18.2;Late spermatids: 32.8;Proximal tubular cells: 17.9;Respiratory ciliated cells: 35.7;Spermatocytes: 70.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HaCaT: 3.0;SiHa: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA038131 Approved Approved Vesicles,Microtubules,Mitochondria NA No "Cluster 35: T-regs - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Vesicles, Microtubules, Mitochondria" "HPA038131: AB_10670658" "unprognostic (4.76e-4)" "unprognostic (2.38e-1)" "unprognostic (3.75e-2)" "unprognostic (2.92e-2)" "unprognostic (9.67e-3)" "unprognostic (1.91e-1)" "unprognostic (1.54e-1)" "unprognostic (1.78e-2)" "unprognostic (8.56e-2)" "unprognostic (1.78e-1)" "unprognostic (1.24e-2)" "unprognostic (2.46e-3)" "unprognostic (3.98e-1)" "unprognostic (3.59e-2)" "unprognostic (3.84e-3)" "unprognostic (9.58e-2)" 0.0 0.2 1.5 0.2 1.4 0.3 0.1 0.9 1.6 0.1 5.1 0.1 0.5 0.2 1.4 0.1 4.8 0.2 0.7 1.7 1.3 3.5 0.4 2.9 0.3 2.0 2.2 0.5 0.2 0.4 1.2 0.1 1.5 0.0 0.0 0.9 0.1 0.1 0.5 1.3 0.3 0.0 1.3 0.2 0.1 12.4 1.9 0.0 0.6 0.1 0.1 0.0 0.0 2.0 0.7 0.1 0.9 0.1 0.0 0.2 0.3 0.1 0.0 0.9 0.8 0.2 1.3 0.1 0.1 0.8 0.1 3.0 0.1 0.3 0.8 0.3 0.2 0.3 0.7 0.2 0.5 0.1 0.2 0.2 1.0 0.3 0.4 0.1 0.0 0.1 0.3 0.5 0.0 0.3 0.1 0.2 0.5 0.0 0.1 0.1 0.1 0.1 0.7 0.2 0.5 0.2 3.9 0.1 0.0 0.1 0.2 0.2 0.2 0.2 0.8 0.2 0.1 0.5 0.1 0.0 1.1 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.1 0.2 0.3 0.2 0.0 0.3 0.2 0.2 0.0 0.2 0.1 0.2 1.2 0.0 1.5 1.4 0.9 1.6 1.7 1.3 2.0 2.2 1.5 1.3 1.9 2.0 0.0 38.5 2.4 0.3 0.0 2.8 0.1 1.9 0.0 0.4 0.0 0.0 1.8 0.0 2.5 0.0 0.0 0.0 0.0 0.0 1.9 0.2 40.2 18.2 0.2 0.1 0.0 0.0 4.7 0.2 0.0 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 32.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 2.2 0.2 0.0 0.7 0.0 0.0 0.0 17.9 35.7 1.6 6.6 0.0 0.1 70.1 5.2 0.0 1.3 0.0 0.3 0.5 0.1 0.0 C1orf116 "FLJ36507, MGC2742, MGC4309, SARG" ENSG00000182795 "Chromosome 1 open reading frame 116" Q9BW04 1 207018522-207032756 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 102.3;lung: 72.9;stomach 1: 58.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 176.3;Alveolar cells type 2: 99.4;Club cells: 68.5;Urothelial cells: 128.1" "Cancer enhanced" "Detected in many" "prostate cancer: 65.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 57.7;CAPAN-2: 99.5;HaCaT: 123.1;HBEC3-KT: 118.6;hTCEpi: 61.4;RPTEC TERT1: 56.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA011888, HPA011889" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 180000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA011888: AB_1853872, HPA011889: AB_1853873" "unprognostic (1.52e-2)" "unprognostic (1.17e-1)" "unprognostic (8.95e-2)" "unprognostic (1.68e-1)" "unprognostic (2.35e-1)" "unprognostic (5.78e-2)" "unprognostic (3.27e-1)" "unprognostic (5.19e-2)" "unprognostic (8.07e-2)" "unprognostic (4.18e-2)" "unprognostic (2.87e-3)" "unprognostic (7.09e-3)" "prognostic favorable (1.01e-5)" "unprognostic (5.17e-1)" "unprognostic (2.48e-1)" "unprognostic (7.57e-3)" "unprognostic (1.19e-1)" 0.2 0.4 0.0 1.6 0.0 0.8 10.4 0.0 0.1 15.1 0.0 8.9 24.5 0.2 0.7 102.3 2.6 9.8 0.5 0.0 0.0 8.4 0.5 72.9 0.0 0.0 0.0 0.1 12.9 0.0 0.3 0.2 0.0 50.9 8.4 0.0 29.4 1.9 0.5 37.7 20.3 0.3 0.0 0.2 58.7 0.9 0.0 0.3 4.2 0.5 16.1 20.6 31.2 0.0 57.7 7.7 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 5.1 99.5 0.0 6.5 0.0 0.0 123.1 0.0 118.6 0.0 0.1 0.0 10.6 1.0 1.6 0.0 0.0 0.6 0.0 61.4 0.0 34.2 0.0 0.0 0.2 6.9 0.1 0.0 0.1 0.1 0.2 0.1 37.3 3.3 0.0 0.0 0.2 56.4 15.1 0.1 0.3 1.1 11.1 0.5 0.4 0.2 0.2 0.0 0.0 0.3 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 176.3 99.4 0.0 0.3 20.8 53.0 26.8 10.8 0.0 5.4 7.2 49.9 30.0 68.5 11.0 0.0 0.1 0.1 40.7 15.6 24.3 5.7 6.7 1.4 1.7 10.7 0.0 0.1 24.4 0.0 1.6 50.4 14.9 6.3 0.0 0.0 0.0 0.2 0.0 0.1 19.8 12.2 0.0 1.2 5.5 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 60.7 35.3 0.0 0.3 56.5 31.8 0.3 41.0 0.0 0.0 0.0 2.8 0.1 0.0 24.3 23.3 0.0 0.3 0.1 8.9 128.1 C1orf162 MGC24133 ENSG00000143110 "Chromosome 1 open reading frame 162" Q8NEQ5 1 111473792-111478512 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 115.0;lymphoid tissue: 134.5" "Cell type enhanced" "Detected in many" "granulocytes: 182.3;Hofbauer cells: 195.3;Kupffer cells: 797.4;Langerhans cells: 226.7;Macrophages: 413.5;monocytes: 278.6;NK-cells: 355.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 8 "HDLM-2: 141.3;HL-60: 70.4;NB-4: 40.3;THP-1: 55.2;U-937: 117.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA026988 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA026988: AB_10600887" "unprognostic (8.79e-2)" "unprognostic (5.18e-3)" "unprognostic (1.14e-2)" "unprognostic (2.11e-1)" "unprognostic (5.20e-2)" "unprognostic (5.96e-2)" "unprognostic (1.61e-1)" "unprognostic (5.66e-2)" "unprognostic (1.11e-1)" "unprognostic (4.69e-2)" "unprognostic (1.86e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (3.14e-6)" "unprognostic (1.29e-2)" "unprognostic (3.15e-2)" "unprognostic (1.53e-1)" "unprognostic (2.74e-1)" 45.4 23.6 16.3 70.8 16.2 115.0 22.3 17.2 29.0 13.2 19.6 15.8 7.3 11.5 6.3 9.8 22.5 31.2 18.1 16.3 18.4 12.5 41.9 85.7 70.4 20.6 17.3 9.4 9.4 4.8 9.1 15.2 19.7 11.7 17.9 9.5 11.2 6.6 10.1 7.8 21.2 37.6 16.7 134.5 12.5 7.6 23.3 27.7 10.0 7.4 55.9 25.1 10.8 21.4 0.3 0.1 0.5 1.1 0.4 0.6 0.6 0.9 0.1 0.3 0.3 0.2 0.4 0.5 0.5 0.2 0.1 0.2 0.8 0.5 0.6 141.3 0.4 0.4 0.5 0.0 0.4 70.4 11.1 0.0 2.6 0.8 0.9 1.0 2.0 0.7 0.5 0.4 0.5 0.5 0.6 40.3 0.2 0.7 0.8 0.1 0.7 0.1 0.3 0.1 0.5 0.2 0.5 0.6 0.8 0.6 0.3 55.2 0.0 0.8 1.0 0.7 0.6 0.6 0.1 0.6 0.3 117.9 1.2 1114.1 1026.8 1294.8 166.6 1529.2 47.6 231.0 206.5 97.3 1021.6 296.4 318.0 193.6 143.3 536.7 1173.4 302.8 66.7 1189.5 16.3 16.2 17.2 29.0 16.3 18.4 20.6 17.3 19.7 16.7 23.3 21.4 4.4 22.4 43.9 8.1 84.1 7.9 0.7 0.4 0.6 4.0 2.2 5.2 3.8 10.0 4.5 7.3 2.1 1.0 103.4 0.6 0.0 0.2 36.7 0.8 0.9 8.1 1.8 23.5 9.2 0.2 2.0 3.2 0.5 1.0 182.3 0.9 15.7 8.9 195.3 0.0 13.0 0.0 0.0 797.4 226.7 90.7 2.8 413.5 12.4 12.2 278.6 0.2 355.3 6.0 7.7 0.2 0.0 0.7 4.2 0.8 0.9 1.0 0.9 4.2 32.9 2.4 2.9 2.4 2.0 0.2 6.5 1.6 59.8 0.3 0.7 0.3 C1orf43 "DKFZp586G1722, NICE-3" ENSG00000143612 "Chromosome 1 open reading frame 43" Q9BWL3 1 154206696-154220637 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010725 Approved Supported Mitochondria,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA010725: AB_1078341" "unprognostic (3.90e-2)" "unprognostic (1.22e-2)" "unprognostic (2.11e-1)" "unprognostic (1.12e-1)" "unprognostic (6.87e-2)" "unprognostic (6.15e-3)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.72e-1)" "unprognostic (2.78e-1)" "unprognostic (2.64e-2)" "unprognostic (3.51e-2)" "unprognostic (1.10e-1)" "unprognostic (1.87e-2)" "unprognostic (1.69e-1)" "unprognostic (2.89e-1)" "unprognostic (1.75e-2)" "unprognostic (1.23e-1)" 126.7 131.9 148.0 72.6 160.4 77.3 119.7 158.9 168.6 90.5 145.1 109.3 118.4 80.7 115.3 107.7 100.5 86.7 179.7 141.7 158.3 187.7 222.0 106.3 82.0 153.0 152.6 77.1 149.7 149.6 85.7 67.6 151.6 94.9 121.2 135.7 99.1 90.2 477.6 105.8 106.1 90.6 152.4 81.6 117.2 62.0 154.2 92.0 108.7 368.2 99.0 113.9 85.7 169.3 183.5 188.4 156.5 185.1 231.1 230.7 96.2 180.2 309.4 205.0 188.4 127.7 249.8 237.9 268.1 162.9 177.5 182.4 218.5 163.3 147.2 191.1 232.1 184.9 182.6 168.1 357.9 235.4 209.6 187.1 376.6 219.8 449.7 278.6 239.9 262.6 199.1 220.1 268.4 287.5 177.4 212.1 302.3 414.8 282.3 159.8 145.8 435.9 256.0 180.6 254.8 333.5 161.1 420.8 624.9 180.8 416.6 513.5 164.4 157.9 133.6 193.3 229.7 403.5 424.1 227.6 263.4 234.4 430.9 189.9 204.8 134.3 85.9 185.4 102.4 100.3 98.7 93.3 211.5 90.0 102.8 86.8 114.9 83.3 174.6 156.2 154.3 242.7 148.0 160.4 158.9 168.6 141.7 158.3 153.0 152.6 151.6 152.4 154.2 169.3 107.2 115.4 100.8 27.1 92.1 94.2 128.4 155.3 81.4 112.6 132.9 114.4 135.8 128.7 115.4 71.7 29.2 87.2 86.8 106.1 252.4 171.5 247.1 69.6 62.1 105.4 122.0 110.0 27.3 202.0 125.1 80.2 77.5 58.1 62.1 79.5 100.6 146.9 178.9 58.9 30.8 133.9 116.0 162.5 116.1 171.8 65.0 131.5 124.5 16.9 155.4 107.0 64.9 26.2 50.5 162.8 131.6 74.9 104.1 186.1 218.3 262.1 85.7 89.5 72.3 75.8 86.6 70.7 59.2 113.9 100.6 126.1 76.7 117.4 133.6 167.5 C1QL1 "C1QRF, C1QTNF14, CRF, CTRP14" ENSG00000131094 "Complement C1q like 1" O75973 17 44959693-44968303 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 134.0" "Cell type enriched" "Detected in some" 7 "Horizontal cells: 673.0" "Cancer enriched" "Detected in all" 7 "glioma: 116.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 34.8;SH-SY5Y: 24.8;U-2 OS: 89.0;U-251 MG: 28.1;U-87 MG: 27.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (6.37e-2)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" "unprognostic (3.63e-3)" "unprognostic (3.15e-2)" "unprognostic (2.05e-2)" "unprognostic (7.65e-2)" "unprognostic (3.40e-3)" "unprognostic (2.34e-1)" "unprognostic (6.64e-3)" "unprognostic (1.49e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (1.31e-8)" "unprognostic (2.67e-2)" "unprognostic (1.05e-1)" "unprognostic (1.61e-2)" "unprognostic (3.04e-1)" 7.7 0.7 18.5 0.4 17.2 0.0 0.9 26.6 32.1 3.0 16.2 4.9 2.0 13.0 0.3 1.8 4.4 0.3 4.1 15.5 21.4 21.0 0.7 0.2 0.0 134.0 41.9 0.7 4.6 0.0 2.1 0.0 24.9 7.3 0.3 8.1 0.7 0.0 0.1 0.5 6.2 0.6 32.4 0.1 3.9 0.8 21.6 0.1 0.3 0.2 0.0 6.4 1.2 24.3 4.6 5.1 1.1 17.8 0.3 0.0 0.3 0.8 0.7 0.5 1.6 0.7 0.6 0.2 3.0 0.4 5.3 0.6 2.8 0.2 0.2 12.7 7.5 0.0 7.9 0.1 2.1 0.0 2.2 0.4 0.0 0.7 0.2 6.2 0.0 3.1 0.1 0.2 0.5 1.1 4.0 0.1 3.1 0.5 10.7 6.7 0.2 0.3 0.1 0.4 34.8 24.8 15.6 1.3 1.3 0.9 4.1 0.2 0.1 1.4 89.0 0.9 28.1 1.0 0.0 0.1 27.8 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.5 17.2 26.6 32.1 15.5 21.4 134.0 41.9 24.9 32.4 21.6 24.3 0.1 0.0 0.0 4.2 0.0 0.3 0.2 1.0 0.0 22.3 0.4 3.2 1.1 5.7 0.0 0.0 10.4 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.5 0.4 5.3 0.0 0.5 0.0 0.1 1.9 0.0 0.5 0.0 0.3 1.1 0.1 0.0 673.0 11.7 0.0 0.0 0.3 0.0 0.2 0.3 0.1 0.0 1.0 0.0 17.6 0.0 84.4 0.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 14.5 0.0 0.0 0.7 0.2 1.0 0.2 0.0 0.0 0.2 0.1 0.0 0.1 C1R ENSG00000159403 "Complement C1r" 12 7080214-7092540 "Human disease related genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "liver: 1425.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 442.3;Fibroblasts: 684.4;Hepatocytes: 1444.2;Leydig cells: 1142.6;Peritubular cells: 388.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1089.8;ASC TERT1: 546.0;BJ hTERT+: 461.9;BJ hTERT+ SV40 Large T+ RasG12V: 303.4;HSkMC: 672.1" "Low region specificity" "Detected in many" "HPA001251, HPA001551" Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA001251: AB_2666252, HPA001551: AB_10754818" "unprognostic (1.55e-2)" "unprognostic (8.97e-2)" "unprognostic (3.46e-2)" "unprognostic (1.92e-1)" "unprognostic (1.47e-2)" "unprognostic (2.66e-2)" "unprognostic (1.94e-2)" "unprognostic (2.05e-1)" "unprognostic (2.50e-1)" "unprognostic (1.72e-1)" "unprognostic (1.21e-1)" "unprognostic (4.16e-2)" "prognostic unfavorable (1.94e-14)" "unprognostic (3.54e-2)" "unprognostic (2.25e-2)" "unprognostic (6.13e-2)" "unprognostic (2.59e-2)" 540.6 203.6 15.8 122.4 15.9 1.1 400.6 15.9 23.3 470.5 21.7 277.3 38.3 353.8 80.8 119.0 526.3 279.1 458.7 15.4 19.6 148.9 1425.6 340.3 72.4 23.4 19.9 644.3 88.0 11.0 63.9 52.4 18.4 205.2 100.9 5.8 158.3 87.0 69.4 177.7 228.1 157.7 18.1 192.1 242.7 46.7 18.1 34.7 223.4 74.2 75.3 468.4 394.3 18.0 1.2 8.9 0.9 9.1 1089.8 546.0 0.4 108.9 461.9 143.0 303.4 1.4 2.4 0.5 4.5 108.8 11.8 2.3 11.8 5.5 18.3 18.3 1.1 0.5 4.1 3.6 226.5 0.8 2.3 672.1 3.2 74.7 4.7 121.0 2.9 0.5 0.3 20.5 21.2 0.1 8.0 0.8 3.1 0.1 0.9 8.6 3.8 0.8 0.9 5.5 0.4 2.3 95.1 3.7 2.8 1.3 0.2 0.2 0.4 38.3 6.3 152.1 0.8 1.1 3.0 0.2 53.1 1.0 5.4 0.0 0.0 0.6 0.3 0.0 0.5 0.0 0.2 0.7 0.0 0.0 0.6 0.6 0.5 0.8 0.0 0.0 0.3 0.1 15.8 15.9 15.9 23.3 15.4 19.6 23.4 19.9 18.4 18.1 18.1 18.0 45.4 22.4 90.5 3.6 7.1 54.7 58.8 76.6 33.6 0.3 5.9 30.9 20.8 183.0 22.9 18.4 2.1 4.1 1.8 0.7 3.9 280.8 4.6 13.3 442.3 45.4 0.0 40.6 0.9 44.5 3.7 684.4 16.3 11.6 10.1 24.9 114.9 1444.2 11.2 0.0 0.3 0.7 0.0 40.9 66.9 29.2 1142.6 7.0 53.4 13.1 1.6 16.0 0.0 2.5 0.1 51.1 1.3 388.1 6.2 17.7 0.3 6.1 5.3 1.4 170.9 87.5 140.4 6.8 6.7 5.6 40.1 5.2 11.5 15.2 0.7 11.2 C2 ENSG00000166278 "Complement C2" P06681 6 31897785-31945672 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 477.9" "Group enriched" "Detected in many" 4 "Alveolar cells type 2: 142.4;Hepatocytes: 380.3;Hofbauer cells: 282.7;Kupffer cells: 99.3" "Cancer enriched" "Detected in all" 9 "liver cancer: 100.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "intermediate monocyte: 21.1;non-classical monocyte: 25.9" "Lineage enriched" "Detected in single" 35 "monocytes: 25.9" "Cell line enriched" "Detected in some" 5 "Karpas-707: 284.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB016775 Supported "Secreted to blood" NA NA 34000000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 15: Hepatocytes - Hemostasis" "CAB016775: " "unprognostic (2.05e-1)" "unprognostic (1.22e-1)" "unprognostic (7.68e-2)" "unprognostic (1.49e-3)" "unprognostic (7.40e-2)" "unprognostic (3.34e-2)" "unprognostic (1.36e-2)" "unprognostic (8.88e-3)" "unprognostic (3.02e-1)" "unprognostic (2.59e-3)" "unprognostic (3.27e-2)" "unprognostic (3.15e-3)" "prognostic unfavorable (2.64e-7)" "unprognostic (2.05e-1)" "unprognostic (4.42e-2)" "unprognostic (7.37e-2)" "unprognostic (2.55e-2)" 42.6 12.1 0.8 27.6 1.0 3.2 11.7 0.9 1.4 8.1 1.7 14.3 16.7 7.0 1.3 7.6 12.0 23.0 8.5 0.7 1.1 23.2 477.9 80.0 27.8 3.0 2.6 5.3 1.9 0.9 3.8 48.4 3.0 5.4 13.0 0.4 9.1 0.9 2.1 5.8 30.2 23.6 2.1 46.3 12.0 4.1 3.7 5.5 3.3 2.7 12.5 23.6 5.3 2.1 0.3 0.1 0.1 0.6 0.1 0.0 6.8 0.5 0.3 0.4 0.3 0.4 0.3 0.6 3.5 1.0 0.6 0.5 0.1 0.0 0.3 0.2 0.4 0.3 0.4 52.8 1.1 0.1 0.7 2.7 0.3 0.6 0.1 0.6 0.0 0.7 0.5 284.0 0.0 0.0 0.4 0.5 0.3 0.1 0.0 0.2 16.5 3.0 0.0 0.1 0.3 0.3 2.6 0.3 0.2 0.3 0.2 9.5 0.2 0.2 0.7 0.5 0.1 0.9 31.6 2.7 0.8 0.9 0.1 0.1 5.6 0.0 0.1 21.1 0.1 0.0 0.0 0.0 0.7 0.1 0.1 0.1 0.5 0.1 25.9 0.0 0.0 2.2 0.8 1.0 0.9 1.4 0.7 1.1 3.0 2.6 3.0 2.1 3.7 2.1 2.1 25.6 142.4 2.6 1.9 3.3 1.1 2.0 0.6 1.4 1.3 1.3 0.6 25.8 11.2 1.8 0.0 2.1 0.1 1.8 0.0 0.6 0.3 1.5 18.7 1.9 2.4 10.7 6.6 2.7 2.7 19.8 3.1 1.3 3.8 0.2 21.0 380.3 282.7 1.7 6.3 11.3 0.0 99.3 5.0 1.3 6.8 32.6 3.6 7.5 7.3 0.1 0.0 1.0 1.7 4.5 33.1 1.2 0.4 4.0 55.2 35.7 9.4 0.9 0.0 5.6 3.5 0.8 1.4 0.7 2.8 4.0 2.0 0.5 15.8 4.5 C2CD3 DKFZP586P0123 ENSG00000168014 "C2 domain containing 3 centriole elongation regulator" Q4AC94 11 74012718-74171210 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 70.5;Alveolar cells type 2: 114.6;Excitatory neurons: 57.4;Respiratory ciliated cells: 57.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 17.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 60.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038552, HPA038553, HPA040433" Approved Approved Nucleoplasm,Centrosome NA NA "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Centrosome" "HPA038552: AB_10669542, HPA038553: AB_2676080, HPA040433: AB_2676981" "unprognostic (3.94e-1)" "unprognostic (7.89e-2)" "unprognostic (3.68e-2)" "unprognostic (8.86e-3)" "unprognostic (1.31e-1)" "unprognostic (1.18e-1)" "unprognostic (8.48e-5)" "unprognostic (1.99e-1)" "unprognostic (4.96e-3)" "unprognostic (2.20e-1)" "unprognostic (1.74e-1)" "unprognostic (5.86e-2)" "unprognostic (2.21e-1)" "unprognostic (1.91e-1)" "unprognostic (3.11e-1)" "unprognostic (1.18e-1)" "unprognostic (2.92e-1)" 3.9 4.7 15.4 5.1 14.8 9.9 3.7 21.7 22.9 4.2 16.7 4.0 3.9 4.8 4.5 3.9 7.8 3.7 2.9 18.5 14.4 4.9 5.8 4.2 5.0 16.9 13.8 4.7 2.2 6.2 3.7 5.9 15.3 4.3 5.2 8.2 4.3 3.5 3.5 6.0 4.2 4.2 11.2 5.9 4.3 11.0 15.8 7.7 7.0 3.4 5.4 3.9 2.7 19.4 9.3 14.3 11.7 14.3 5.2 4.8 5.6 13.7 8.8 16.0 13.0 24.4 7.4 9.0 9.2 5.2 15.5 13.9 14.7 3.8 19.3 12.4 7.0 12.4 21.3 10.8 8.8 12.0 16.9 4.8 4.8 13.4 9.7 5.1 9.0 11.1 14.2 15.7 13.3 7.7 14.1 8.3 9.4 17.8 7.7 14.3 60.4 9.0 4.6 13.0 15.6 9.2 22.4 8.4 21.2 11.9 16.5 7.8 12.7 10.3 17.0 10.1 11.0 11.7 8.5 26.1 4.0 6.0 11.1 17.8 2.0 3.0 2.2 2.3 2.0 2.3 1.4 1.8 1.3 4.4 2.1 2.1 12.6 2.9 4.7 2.0 1.0 0.7 15.4 14.8 21.7 22.9 18.5 14.4 16.9 13.8 15.3 11.2 15.8 19.4 6.5 70.5 114.6 28.1 10.5 5.2 3.6 4.8 9.6 8.7 6.2 5.8 5.1 4.3 36.0 9.2 4.2 3.8 5.6 7.6 0.0 4.0 33.0 18.4 9.4 9.8 7.7 12.2 57.4 2.6 2.9 9.6 15.3 8.9 36.6 8.5 5.0 3.0 5.0 11.8 52.1 5.0 4.1 7.6 6.6 24.7 4.4 12.7 7.2 26.2 4.9 4.8 10.3 37.7 38.5 3.8 2.8 6.4 9.5 3.4 3.4 1.8 57.1 14.8 6.6 7.2 5.2 11.1 6.9 6.4 4.5 2.3 14.0 5.4 5.4 4.7 C2CD4B "FAM148B, NLF2" ENSG00000205502 "C2 calcium dependent domain containing 4B" A6NLJ0 15 62163535-62165285 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "pancreas: 99.3" "Cell type enhanced" "Detected in many" "Adipocytes: 169.8;Endothelial cells: 116.2;Enteroendocrine cells: 214.4;Glandular and luminal cells: 128.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HUVEC TERT2: 1.9" HPA046880 Uncertain NA NA "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "HPA046880: AB_10959458" "unprognostic (6.60e-2)" "prognostic favorable (4.22e-4)" "unprognostic (2.24e-2)" "unprognostic (1.25e-1)" "unprognostic (4.15e-1)" "unprognostic (4.06e-3)" "unprognostic (2.29e-1)" "unprognostic (5.02e-2)" "unprognostic (3.36e-2)" "unprognostic (2.33e-1)" "unprognostic (5.30e-2)" "unprognostic (1.83e-1)" "unprognostic (6.16e-3)" "unprognostic (7.89e-2)" "unprognostic (5.24e-1)" "unprognostic (8.64e-3)" "unprognostic (1.48e-1)" 23.1 1.2 1.5 0.6 1.0 3.0 19.6 0.8 1.2 7.2 0.5 2.5 2.2 4.1 0.0 1.6 2.8 1.6 6.3 0.9 0.9 5.5 1.9 13.0 0.4 1.5 1.3 1.0 99.3 0.3 6.5 0.4 1.5 2.3 0.4 0.0 1.6 0.2 2.8 4.7 2.4 0.7 1.7 0.5 24.4 1.0 2.1 2.7 2.7 1.3 0.0 5.0 2.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.0 0.8 1.2 0.9 0.9 1.5 1.3 1.5 1.7 2.1 0.9 169.8 3.2 5.5 0.0 0.1 6.8 3.0 0.1 0.6 0.8 14.5 4.3 1.3 5.7 0.9 1.8 0.0 0.0 0.9 6.1 0.0 2.1 0.0 40.4 15.2 116.2 214.4 0.0 0.0 24.0 0.0 3.2 17.9 128.9 2.5 0.0 11.4 0.4 0.4 0.0 0.1 22.5 6.1 1.0 12.1 0.0 0.0 1.3 3.6 1.9 1.6 0.1 0.0 0.0 0.0 9.8 1.3 0.0 0.1 2.4 1.3 0.0 0.1 0.6 0.0 6.8 4.1 0.1 0.4 0.8 7.0 0.0 1.7 0.5 4.3 3.5 C3AR1 "AZ3B, C3AR" ENSG00000171860 "Complement C3a receptor 1" Q16581 12 8056844-8066359 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.1" "Cell type enhanced" "Detected in some" "granulocytes: 36.8;Hofbauer cells: 161.5;Kupffer cells: 139.7;Macrophages: 105.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 898.6;eosinophil: 450.8;intermediate monocyte: 273.6;non-classical monocyte: 371.3" "Group enriched" "Detected in many" 20 "granulocytes: 898.6;monocytes: 371.3" "Cell line enriched" "Detected in some" 9 "HMC-1: 148.0" "Low region specificity" "Detected in many" CAB009405 Enhanced NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009405: AB_2066739" "unprognostic (1.11e-2)" "unprognostic (5.67e-2)" "unprognostic (5.06e-2)" "unprognostic (4.14e-2)" "unprognostic (6.60e-2)" "unprognostic (1.50e-1)" "unprognostic (4.81e-2)" "unprognostic (2.78e-1)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.59e-1)" "unprognostic (3.50e-2)" "unprognostic (8.22e-2)" "unprognostic (4.96e-2)" "unprognostic (9.24e-3)" "unprognostic (2.09e-2)" "unprognostic (8.16e-2)" 18.0 10.6 3.8 40.1 4.0 22.9 6.7 4.7 5.7 6.8 4.4 7.4 6.6 3.8 1.5 3.9 5.9 16.2 4.4 3.9 6.9 3.1 10.8 18.6 12.4 10.1 6.3 3.7 6.0 3.3 2.5 22.0 9.0 3.3 6.8 0.8 5.6 4.3 1.4 2.0 9.7 15.6 8.3 21.4 5.3 2.1 7.8 4.9 2.4 2.6 5.1 15.2 2.7 15.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 1.9 0.5 3.8 0.0 0.0 1.6 0.0 0.0 2.2 0.1 0.0 0.0 0.1 0.0 0.0 12.0 0.0 0.0 1.4 15.6 148.0 0.7 0.0 0.2 0.4 0.3 0.7 1.2 4.0 8.2 0.7 0.0 0.7 5.2 0.1 0.0 0.0 0.1 3.1 15.1 0.7 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 6.6 0.6 0.5 0.4 0.1 0.3 0.3 0.0 0.4 8.5 6.4 0.4 898.6 105.0 450.8 21.8 273.6 26.9 0.2 10.6 14.5 31.1 0.3 2.0 7.8 14.0 4.1 371.3 2.8 11.0 76.0 3.8 4.0 4.7 5.7 3.9 6.9 10.1 6.3 9.0 8.3 7.8 15.6 0.7 0.0 3.0 0.3 1.1 0.5 0.1 0.1 0.0 0.1 0.3 0.9 0.6 1.5 2.5 0.0 2.1 0.7 5.9 0.0 0.0 0.0 3.0 0.0 0.1 6.6 0.0 0.8 0.4 0.2 1.0 0.6 0.0 0.0 36.8 0.0 1.8 0.8 161.5 0.0 0.3 0.0 0.0 139.7 19.8 4.2 1.2 105.7 0.0 8.4 16.2 0.0 8.2 0.0 0.2 0.0 0.0 0.0 2.6 0.0 0.0 0.2 0.7 0.4 19.7 0.7 1.0 0.0 0.2 0.0 0.6 1.5 8.6 0.1 0.0 0.0 C3orf52 "FLJ23186, TTMP" ENSG00000114529 "Chromosome 3 open reading frame 52" Q5BVD1 3 112086335-112131004 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 17.4;skin 1: 26.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 129.6;Pancreatic endocrine cells: 82.8;Prostatic glandular cells: 75.6;Syncytiotrophoblasts: 75.0;Urothelial cells: 132.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 26.4;U-698: 30.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007678, HPA008119, HPA011968" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Nuclear bodies, Cytosol" "HPA007678: , HPA008119: AB_1848824, HPA011968: AB_1848826" "unprognostic (8.86e-2)" "unprognostic (1.71e-1)" "unprognostic (3.58e-2)" "unprognostic (7.97e-2)" "unprognostic (1.45e-2)" "unprognostic (3.87e-3)" "unprognostic (3.49e-4)" "unprognostic (2.54e-1)" "unprognostic (1.39e-2)" "unprognostic (2.30e-1)" "prognostic unfavorable (3.85e-4)" "unprognostic (2.71e-2)" "unprognostic (3.76e-6)" "unprognostic (3.14e-1)" "unprognostic (2.05e-1)" "unprognostic (1.75e-2)" "unprognostic (9.59e-2)" 1.2 1.0 0.1 1.2 0.2 0.6 2.7 0.2 0.3 0.7 0.2 7.5 3.3 0.9 0.0 2.6 0.7 5.0 4.0 0.2 0.1 4.8 0.3 3.8 1.2 0.0 0.1 0.2 17.4 0.0 2.0 3.3 0.1 1.7 13.7 0.1 3.8 3.4 0.5 26.3 5.2 0.9 0.1 0.7 13.7 0.9 0.3 6.6 7.6 0.1 2.0 5.8 1.6 0.1 11.0 2.0 4.2 0.0 0.6 0.0 1.8 15.5 6.7 10.1 11.3 26.4 10.1 0.4 1.9 3.1 4.4 8.7 6.1 0.3 19.4 0.0 2.8 7.9 1.8 1.9 4.6 0.0 0.1 0.6 8.7 5.2 15.0 5.4 2.2 0.0 2.8 2.8 7.5 1.7 0.3 0.0 12.3 7.9 0.6 0.3 13.2 0.0 18.1 16.5 0.5 0.9 2.4 5.2 6.3 6.8 9.5 0.0 5.8 3.6 5.5 0.0 0.0 3.9 0.0 30.1 2.7 0.1 3.6 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.4 0.2 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.2 0.2 0.3 0.2 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.8 16.0 10.0 0.3 1.6 32.5 129.6 10.0 45.5 0.0 14.8 3.3 2.1 4.3 19.3 18.4 0.0 18.1 0.7 30.4 0.0 26.3 24.2 24.8 3.1 3.5 11.9 0.0 3.2 35.9 25.6 4.7 64.2 44.1 0.0 0.4 0.4 0.0 1.9 0.0 0.6 56.6 8.2 0.3 2.7 23.3 0.3 1.0 1.8 1.0 2.6 0.0 0.0 0.5 0.3 82.8 30.7 0.4 4.6 75.6 7.8 2.1 14.8 0.0 0.0 4.6 4.7 3.2 5.3 44.0 33.5 75.0 2.0 3.0 8.9 132.5 C4A "C4, C4A2, C4A3, C4A4, C4A6, C4B, C4S, CO4, CPAMD2, RG" ENSG00000244731 "Complement C4A (Rodgers blood group)" P0C0L4 6 31982057-32002681 "Blood group antigen proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Inflammatory response, Innate immunity" "Blood group antigen" "Disease variant, FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 115.8;liver: 336.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 46.4;Cardiomyocytes: 8.3;Club cells: 13.6;Fibroblasts: 19.1" "Cancer enhanced" "Detected in many" "liver cancer: 27.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 58.5;HSkMC: 72.8;U-266/70: 17.1;U-266/84: 33.9" "CAB009811, CAB032603, HPA046356, HPA048287, HPA050103" Supported "Secreted to blood" NA NA 342000000 120000000000 "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "CAB009811: AB_2066891, CAB032603: AB_2290613, HPA046356: AB_2679635, HPA048287: AB_2680341, HPA050103: AB_2681016" "unprognostic (2.13e-1)" "unprognostic (3.02e-2)" "unprognostic (3.74e-2)" "unprognostic (3.10e-1)" "unprognostic (5.29e-2)" "unprognostic (3.09e-2)" "unprognostic (2.48e-2)" "unprognostic (1.02e-1)" "unprognostic (2.00e-1)" "unprognostic (1.44e-1)" "unprognostic (3.70e-1)" "unprognostic (3.15e-1)" "unprognostic (4.47e-2)" "unprognostic (3.20e-2)" "unprognostic (5.20e-2)" "unprognostic (3.97e-2)" "unprognostic (8.63e-2)" 27.9 115.8 0.2 10.6 1.6 0.4 15.7 0.3 2.2 12.6 0.2 31.3 7.5 16.9 11.8 2.6 29.9 2.3 21.8 0.5 1.2 43.1 336.8 14.9 4.5 5.8 1.9 57.5 23.0 0.6 20.6 0.5 2.3 11.1 3.7 5.5 14.2 0.0 1.7 1.7 17.0 0.0 0.5 15.3 11.7 4.1 1.7 4.2 44.5 0.0 2.9 23.1 4.1 1.4 0.0 0.3 0.0 0.0 1.0 5.2 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.6 0.7 0.2 0.1 0.1 0.4 0.0 58.5 0.5 0.0 0.3 1.0 0.0 0.0 0.0 72.8 0.0 0.0 0.0 0.5 0.0 0.6 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 3.9 0.0 0.1 0.5 0.0 0.0 0.0 0.0 1.1 0.0 0.2 17.1 33.9 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.3 2.2 0.5 1.2 5.8 1.9 2.3 0.5 1.7 1.4 0.0 9.6 46.4 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 8.3 2.8 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 19.1 0.0 0.0 0.0 0.0 0.4 6.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.5 4.4 0.0 0.0 0.0 2.6 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 C4B "C4B1, C4B3, C4F, CH, CO4, CPAMD3" ENSG00000224389 "Complement C4B (Chido blood group)" P0C0L5 6 32014795-32035418 "Blood group antigen proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Inflammatory response, Innate immunity" "Blood group antigen" "FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 221.5;liver: 385.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 103.9;Cardiomyocytes: 71.8;Club cells: 22.9;Fibroblasts: 53.9" "Cancer enhanced" "Detected in many" "liver cancer: 33.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "Karpas-707: 129.8" "HPA046356, HPA048287, HPA050103" Approved "Secreted to blood" NA NA 120000000000 "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "HPA046356: AB_2679635, HPA048287: AB_2680341, HPA050103: AB_2681016" "unprognostic (1.29e-1)" "unprognostic (2.99e-2)" "unprognostic (5.50e-3)" "unprognostic (1.30e-1)" "unprognostic (8.09e-2)" "unprognostic (6.24e-2)" "unprognostic (6.09e-2)" "unprognostic (1.05e-1)" "unprognostic (4.81e-2)" "unprognostic (1.12e-1)" "unprognostic (6.24e-2)" "unprognostic (6.86e-2)" "unprognostic (1.04e-1)" "unprognostic (3.12e-2)" "unprognostic (1.30e-1)" "unprognostic (3.99e-3)" "unprognostic (1.11e-2)" 29.7 221.5 4.0 0.4 2.5 0.6 15.9 2.5 2.3 10.3 2.4 27.3 2.0 16.6 0.0 2.2 24.0 5.9 22.7 3.2 13.3 39.8 385.2 13.6 2.7 7.1 12.4 56.5 25.1 1.1 20.1 1.6 7.7 10.2 6.0 2.5 21.0 1.2 1.3 1.1 16.6 9.7 9.9 16.3 10.3 3.1 11.8 7.5 49.1 0.2 4.3 18.5 3.7 11.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 21.0 7.8 0.5 0.0 26.2 0.1 0.0 0.0 2.6 0.0 0.0 0.0 129.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 2.5 2.5 2.3 3.2 13.3 7.1 12.4 7.7 9.9 11.8 11.6 0.0 3.2 103.9 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 71.8 1.5 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.6 0.0 0.0 0.0 0.2 0.0 53.9 0.0 0.0 1.3 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.6 0.1 0.0 0.5 8.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 C4orf19 FLJ11017 ENSG00000154274 "Chromosome 4 open reading frame 19" Q8IY42 4 37453925-37623495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 36.0" "Cell type enhanced" "Detected in many" "Astrocytes: 45.4;Distal enterocytes: 61.3;Exocrine glandular cells: 51.8;Oligodendrocyte precursor cells: 46.8;Pancreatic endocrine cells: 53.6;Paneth cells: 67.2;Proximal enterocytes: 52.3;Syncytiotrophoblasts: 47.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 8.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.6" "Group enriched" "Detected in some" 5 "OE19: 64.6;RT4: 81.0;SK-BR-3: 32.6;T-47d: 113.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043458, HPA052894" Enhanced Supported "Cell Junctions" No No "Cluster 1: Neutrophils - Mixed function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" "HPA043458: AB_10960696, HPA052894: AB_2681982" "unprognostic (8.83e-2)" "unprognostic (7.86e-2)" "unprognostic (3.00e-3)" "unprognostic (2.04e-2)" "unprognostic (2.23e-1)" "unprognostic (3.59e-3)" "unprognostic (5.55e-2)" "unprognostic (2.29e-1)" "unprognostic (6.66e-2)" "unprognostic (9.96e-2)" "unprognostic (1.35e-1)" "unprognostic (4.38e-2)" "prognostic favorable (1.49e-11)" "unprognostic (1.33e-1)" "unprognostic (1.60e-1)" "unprognostic (1.63e-3)" "unprognostic (8.19e-3)" 3.4 0.3 2.7 3.0 2.9 3.8 3.8 5.3 4.3 10.2 5.9 25.5 17.7 6.7 0.2 2.1 2.8 9.2 0.4 3.5 4.2 12.4 36.0 3.7 0.5 4.9 4.9 0.2 24.9 16.0 1.2 7.6 4.2 1.7 23.7 4.6 28.2 6.8 0.2 1.6 19.6 4.0 4.5 0.3 20.7 1.4 4.9 0.2 1.5 0.4 4.3 8.8 2.9 4.1 0.1 0.2 3.2 0.3 0.0 0.0 4.2 0.7 0.0 0.0 0.0 12.6 5.2 0.1 3.0 0.0 0.1 0.4 0.2 0.8 0.1 0.0 0.4 0.0 8.3 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.1 14.3 0.2 0.2 0.5 64.6 1.7 0.1 7.8 0.2 12.7 81.0 0.9 0.3 0.5 32.6 1.0 4.0 113.1 0.7 0.6 0.4 4.5 0.2 1.6 0.2 0.1 0.5 0.0 6.9 5.6 0.9 1.4 2.1 0.6 0.2 0.4 0.2 0.3 0.4 0.2 0.5 0.5 0.8 8.6 0.8 0.1 1.6 0.7 0.3 2.7 2.9 5.3 4.3 3.5 4.2 4.9 4.9 4.2 4.5 4.9 4.1 0.3 0.0 12.6 45.4 0.7 0.3 7.8 4.9 0.0 0.6 7.1 3.9 0.2 27.1 10.1 11.0 0.0 6.7 0.2 61.3 11.7 25.2 1.2 9.5 0.4 0.9 9.6 0.0 2.3 51.8 4.7 0.3 33.6 5.5 0.0 0.0 0.0 13.1 0.7 0.0 2.4 28.0 4.1 0.0 0.3 2.4 0.0 0.2 3.6 22.5 0.6 5.3 0.0 46.8 1.8 53.6 67.2 0.0 0.0 7.8 52.3 9.2 12.3 1.0 0.0 0.2 0.9 0.3 0.2 0.5 0.0 47.5 0.4 0.1 31.8 19.1 C5 "C5a, C5b, CPAMD4" ENSG00000106804 "Complement C5" P01031 9 120952335-121050275 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Inflammatory response, Innate immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "liver: 433.7" "Cell type enriched" "Detected in many" 16 "Hepatocytes: 538.3" "Cancer enriched" "Detected in many" 17 "liver cancer: 73.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 28.4;Hep G2: 30.4" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA029339 Supported "Secreted to blood" NA NA 113000000000 39000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA029339: AB_10601125" "unprognostic (2.51e-1)" "unprognostic (5.88e-3)" "unprognostic (2.50e-3)" "unprognostic (1.57e-2)" "unprognostic (5.05e-2)" "unprognostic (9.52e-3)" "prognostic favorable (9.43e-4)" "unprognostic (1.83e-1)" "unprognostic (3.19e-2)" "unprognostic (1.55e-1)" "unprognostic (2.35e-2)" "unprognostic (4.41e-2)" "unprognostic (1.46e-5)" "unprognostic (5.91e-2)" "unprognostic (1.20e-1)" "unprognostic (3.67e-2)" "unprognostic (2.75e-1)" 2.9 1.7 2.5 1.1 3.4 2.2 2.5 2.4 2.6 3.0 3.5 2.8 3.9 2.7 2.7 1.6 3.0 1.5 1.3 2.2 2.6 4.8 433.7 7.0 2.1 2.9 2.9 3.3 14.9 2.6 3.1 0.9 3.2 3.2 1.6 3.5 1.4 2.2 0.5 3.8 3.9 1.9 2.8 1.5 5.8 1.6 2.8 1.2 2.0 1.2 1.7 2.6 2.1 4.5 1.6 28.4 6.4 11.3 8.0 9.2 0.2 3.4 3.5 0.9 2.0 0.8 2.8 4.1 0.1 1.8 3.8 11.0 0.3 0.3 1.5 0.9 0.0 1.8 1.5 30.4 1.5 1.0 0.7 4.1 0.5 2.0 3.7 1.8 1.0 1.6 0.7 3.8 2.2 5.6 0.4 0.2 1.7 7.0 10.9 2.5 2.8 0.4 1.7 0.8 1.6 6.5 1.6 0.0 2.7 4.4 2.2 3.7 1.3 2.8 0.2 7.5 3.4 2.3 1.8 1.7 2.2 3.8 6.8 0.0 0.3 0.4 0.0 0.0 0.2 0.3 0.1 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.5 3.4 2.4 2.6 2.2 2.6 2.9 2.9 3.2 2.8 2.8 4.5 0.8 6.4 28.6 30.0 3.5 1.0 1.0 0.5 1.8 4.8 2.2 1.3 0.8 32.9 7.1 1.8 0.0 0.1 0.1 0.4 1.9 0.2 1.8 1.1 2.2 1.4 0.0 12.0 7.3 0.4 0.0 2.9 2.0 0.8 0.0 3.1 7.5 538.3 1.9 6.7 9.4 1.0 0.0 16.3 1.0 2.8 3.1 3.5 0.0 6.5 2.3 3.2 2.1 25.6 25.4 0.7 3.8 9.1 0.1 0.7 1.0 6.8 3.8 2.6 0.0 4.0 1.6 7.5 2.5 2.0 1.3 0.0 1.4 2.8 2.0 0.6 C6orf132 bA7K24.2 ENSG00000188112 "Chromosome 6 open reading frame 132" Q5T0Z8 6 42101119-42142620 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 157.0;skin 1: 73.6" "Cell type enhanced" "Detected in many" "Late spermatids: 163.8;Pancreatic endocrine cells: 219.9;Prostatic glandular cells: 144.6;Urothelial cells: 226.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 57.8;CACO-2: 52.0;CAPAN-2: 44.0;OE19: 181.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA044588 Enhanced Approved "Golgi apparatus,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Golgi apparatus, Cytosol" "HPA044588: AB_10794293" "unprognostic (7.09e-2)" "unprognostic (8.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.24e-3)" "unprognostic (1.60e-2)" "unprognostic (1.24e-2)" "unprognostic (1.15e-1)" "unprognostic (6.78e-2)" "unprognostic (1.59e-1)" "unprognostic (2.30e-2)" "prognostic unfavorable (4.90e-4)" "unprognostic (1.31e-1)" "unprognostic (4.26e-3)" "unprognostic (1.04e-2)" "unprognostic (5.53e-2)" "unprognostic (2.47e-2)" "unprognostic (1.30e-1)" 3.7 1.0 0.4 2.2 0.4 1.0 8.7 0.6 0.7 31.7 0.3 14.1 33.4 1.0 0.1 157.0 5.8 6.6 1.8 0.4 0.1 14.9 0.5 5.8 0.3 0.4 0.1 0.2 18.0 2.5 1.7 1.5 0.4 12.1 11.7 0.9 47.1 2.3 0.9 73.6 20.7 0.5 0.0 0.1 36.2 0.7 0.3 0.7 10.7 0.3 13.9 9.9 54.9 0.6 57.8 0.5 0.0 0.1 0.3 6.1 29.0 2.9 4.4 7.6 7.6 52.0 44.0 0.0 5.4 5.4 0.1 37.5 0.1 17.3 5.2 5.1 7.2 2.8 5.0 12.1 2.0 0.0 0.2 4.0 30.4 5.9 8.8 3.1 0.0 0.3 1.7 0.5 1.7 20.4 0.4 0.3 3.6 181.7 1.5 0.1 0.0 0.3 6.2 25.5 3.0 0.1 4.7 35.2 0.1 4.1 25.2 0.3 0.8 0.4 3.5 13.5 0.2 0.1 0.1 0.2 0.1 0.2 0.1 0.5 0.2 0.3 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.5 0.1 0.0 0.3 0.0 0.1 0.4 0.4 0.6 0.7 0.4 0.1 0.4 0.1 0.4 0.0 0.3 0.6 0.8 44.8 16.6 0.3 0.2 52.5 88.6 31.8 19.4 0.8 41.7 19.8 5.1 45.8 63.1 51.5 20.9 12.4 1.2 89.9 0.0 57.9 22.2 91.9 9.4 2.8 7.3 0.0 0.5 134.7 1.0 9.2 57.1 135.8 1.3 18.3 1.4 0.0 0.8 5.0 0.5 41.3 38.7 1.2 6.8 163.8 0.6 1.5 12.4 0.0 3.8 0.5 4.1 0.5 0.2 219.9 66.8 1.5 0.3 144.6 102.7 7.7 92.1 7.9 0.0 7.9 4.9 4.9 9.1 81.4 82.0 4.1 1.5 45.4 43.7 226.0 C7 ENSG00000112936 "Complement C7" P10643 5 40909497-40984643 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 735.4" "Group enriched" "Detected in many" 4 "Fibroblasts: 578.4;Hepatic stellate cells: 662.5;Leydig cells: 1058.5;Sertoli cells: 309.0;Theca cells: 503.1" "Cancer enriched" "Detected in all" 4 "pancreatic cancer: 73.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "ASC diff: 116.5;HHSteC: 155.1;HSkMC: 212.1;SH-SY5Y: 146.7" "Not detected" "Not detected" "Region enhanced" "Detected in many" "spinal cord: 13.7" HPA001465 Approved "Secreted to blood" NA NA 48000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA001465: AB_1078554" "unprognostic (5.01e-2)" "unprognostic (3.74e-2)" "unprognostic (7.40e-2)" "unprognostic (4.68e-3)" "unprognostic (5.35e-2)" "unprognostic (1.43e-3)" "prognostic favorable (5.89e-4)" "unprognostic (6.67e-2)" "unprognostic (3.45e-1)" "unprognostic (2.21e-2)" "unprognostic (1.33e-1)" "unprognostic (1.93e-3)" "unprognostic (2.24e-2)" "unprognostic (6.10e-3)" "unprognostic (1.12e-1)" "unprognostic (2.14e-1)" "unprognostic (2.06e-3)" 470.9 607.7 2.6 21.7 3.5 0.2 46.4 2.6 9.6 118.5 13.6 165.3 19.3 124.6 163.6 52.9 377.3 211.7 558.7 2.8 2.5 298.1 110.6 206.7 99.2 4.4 2.7 735.4 149.8 15.0 23.1 359.2 3.0 101.6 32.5 1.5 18.0 105.7 4.3 12.6 139.8 256.3 4.3 138.2 120.2 28.0 3.0 32.2 105.1 1.6 22.5 122.1 118.3 3.0 0.0 0.0 0.0 0.0 116.5 16.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 155.1 0.0 0.0 212.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 146.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.6 3.5 2.6 9.6 2.8 2.5 4.4 2.7 3.0 4.3 3.0 3.0 7.9 6.4 4.1 0.0 1.4 0.6 0.5 0.0 1.8 2.1 1.2 0.3 56.7 7.2 2.5 0.0 0.0 0.2 0.1 0.4 0.0 0.2 4.7 0.5 7.9 127.6 54.8 26.7 0.1 1.3 0.1 578.4 0.0 0.2 1.3 2.7 662.5 8.3 0.5 43.7 0.3 1.3 0.0 14.5 4.2 29.8 1058.5 1.5 0.0 58.1 0.6 3.7 0.0 0.0 0.0 0.9 0.9 18.0 1.0 1.3 0.2 0.1 0.0 0.9 309.0 2.2 23.7 2.6 2.5 6.5 0.6 0.3 1.2 503.1 3.0 0.8 C9orf64 MGC10999 ENSG00000165118 "Chromosome 9 open reading frame 64" Q5T6V5 9 83938311-83956986 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054903, HPA066190" Uncertain Approved "Golgi apparatus" NA NA 9400 "Cluster 15: NK-cells - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "HPA054903: AB_2682636, HPA066190: AB_2685633" "unprognostic (2.07e-1)" "unprognostic (3.17e-1)" "unprognostic (2.28e-1)" "unprognostic (1.53e-1)" "unprognostic (2.51e-3)" "unprognostic (1.04e-1)" "unprognostic (4.00e-3)" "unprognostic (2.20e-2)" "unprognostic (4.45e-2)" "unprognostic (1.21e-1)" "unprognostic (2.90e-2)" "unprognostic (1.35e-1)" "prognostic favorable (4.23e-4)" "unprognostic (1.49e-2)" "unprognostic (3.89e-1)" "unprognostic (1.63e-2)" "unprognostic (8.48e-3)" 8.1 9.2 4.7 8.4 5.6 2.3 7.9 5.1 5.6 8.9 11.0 7.9 23.6 10.2 11.3 5.9 11.4 6.3 8.4 4.8 5.8 13.5 24.5 8.8 8.4 5.7 6.0 10.9 6.1 14.0 4.6 8.0 5.7 8.8 8.2 5.5 6.6 8.7 7.7 4.3 22.1 10.4 5.3 6.6 9.7 8.2 5.5 10.0 16.1 7.1 8.1 7.7 4.9 6.7 23.4 19.7 0.3 0.1 9.9 13.4 23.7 15.0 4.3 14.2 15.8 17.9 20.5 0.1 12.5 16.9 5.7 14.2 0.0 0.5 18.4 25.2 13.1 10.4 25.6 34.9 22.8 0.0 30.1 15.4 19.8 13.6 0.0 3.2 9.3 0.1 25.3 0.3 17.4 23.0 4.9 0.8 18.7 14.8 9.6 0.1 29.9 1.1 11.4 3.7 19.2 18.9 27.0 6.4 21.1 0.3 8.4 20.1 2.9 1.7 20.0 31.7 4.4 6.3 0.3 0.9 13.1 0.8 10.2 7.0 10.4 9.8 6.5 11.8 6.2 2.4 4.9 6.6 11.9 3.3 5.3 6.3 4.2 12.6 12.9 8.3 5.8 4.6 4.7 5.6 5.1 5.6 4.8 5.8 5.7 6.0 5.7 5.3 5.5 6.7 6.5 12.8 10.8 2.0 3.6 2.2 4.5 5.2 4.0 4.3 5.5 4.2 5.4 4.3 3.3 3.7 4.2 12.7 4.1 6.2 11.7 11.6 6.7 11.1 9.0 5.4 4.2 3.4 2.6 8.7 19.4 8.5 8.6 8.4 9.5 6.0 4.6 24.7 12.3 3.3 2.9 7.2 14.2 12.8 4.6 2.9 8.1 8.7 1.8 1.9 13.2 11.9 7.2 3.0 3.8 10.6 10.4 10.9 3.6 3.7 22.1 17.3 6.5 7.3 0.0 11.3 6.7 9.6 5.5 3.7 1.4 4.4 4.2 10.7 10.5 3.0 CA9 "CAIX, MN" ENSG00000107159 "Carbonic anhydrase 9" Q16790 9 35673918-35681159 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "stomach 1: 289.3" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 275.3;Cholangiocytes: 62.9;Early spermatids: 205.8;Gastric mucus-secreting cells: 259.5" "Cancer enhanced" "Detected in many" "renal cancer: 85.9" "Region enriched" "Detected in single" 9 "cerebellum: 5.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "A-431: 189.3;HDLM-2: 98.1;hTERT-RPE1: 113.1;U-87 MG: 374.4" "Region enhanced" "Detected in many" "cerebellum: 12.3" "Low region specificity" "Detected in all" "CAB005100, CAB017107, HPA055207" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 4: Stomach - Digestion" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB005100: AB_2066539, CAB017107: , HPA055207: AB_2682738" "unprognostic (8.01e-3)" "unprognostic (1.34e-2)" "unprognostic (2.28e-1)" "unprognostic (2.00e-2)" "unprognostic (1.59e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.71e-5)" "unprognostic (1.47e-2)" "unprognostic (3.90e-2)" "unprognostic (1.29e-1)" "unprognostic (6.24e-3)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.22e-7)" "unprognostic (7.29e-2)" "prognostic favorable (9.50e-4)" "unprognostic (2.97e-3)" "unprognostic (8.67e-2)" 3.8 0.4 0.0 0.2 0.0 0.0 0.1 5.6 0.6 0.5 0.0 0.6 14.5 0.2 0.1 0.8 0.4 24.4 2.0 0.2 0.1 0.2 1.3 0.2 0.0 0.0 0.1 0.7 6.6 0.0 0.5 0.0 0.2 0.5 0.0 1.0 0.1 0.1 0.1 8.2 13.6 0.1 0.0 0.0 289.3 5.5 0.5 0.0 0.0 0.0 0.0 0.7 0.7 0.0 189.3 0.3 0.0 0.0 0.0 0.0 0.0 0.2 3.6 0.3 2.5 0.0 0.1 0.0 0.1 0.0 0.5 5.7 0.0 0.9 1.5 98.1 0.0 0.0 0.7 0.4 0.0 0.0 0.2 0.4 0.0 0.0 0.3 113.1 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.3 0.2 0.5 0.0 0.0 10.6 0.0 0.6 1.6 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.0 18.9 0.4 0.0 4.7 0.0 0.4 0.1 374.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.6 0.6 0.2 0.1 0.0 0.1 0.2 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.2 4.5 0.7 275.3 0.0 0.4 0.1 0.0 0.4 62.9 28.1 0.0 0.0 0.0 0.0 0.1 0.0 49.1 205.8 0.0 0.1 0.2 0.0 0.0 0.1 50.9 0.6 1.2 259.5 0.2 0.0 0.4 0.7 0.0 0.1 0.0 0.6 4.0 18.3 0.0 0.0 19.6 1.5 0.1 0.0 0.0 0.6 1.3 0.0 0.0 0.0 26.6 0.0 0.7 0.3 0.8 0.7 0.1 5.5 0.0 0.0 0.0 1.5 0.9 4.0 0.0 3.1 0.3 0.1 0.7 5.3 0.4 CABP4 CSNB2B ENSG00000175544 "Calcium binding protein 4" P57796 11 67452406-67461752 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "retina: 68.2" "Group enriched" "Detected in many" 6 "Cone photoreceptor cells: 141.8;Rod photoreceptor cells: 254.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 12.1" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 4 "HMC-1: 19.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (2.24e-1)" "unprognostic (1.26e-1)" "unprognostic (4.23e-2)" "unprognostic (1.22e-2)" "unprognostic (3.78e-3)" "unprognostic (2.91e-2)" "unprognostic (1.03e-3)" "unprognostic (1.76e-1)" "unprognostic (1.49e-1)" "unprognostic (1.44e-2)" "unprognostic (2.32e-3)" "unprognostic (2.57e-1)" "unprognostic (7.10e-4)" "unprognostic (5.35e-2)" "unprognostic (4.63e-2)" "unprognostic (1.10e-1)" "unprognostic (3.44e-3)" 1.2 0.6 1.2 0.5 1.4 0.7 1.4 2.2 1.7 1.4 1.5 0.7 0.6 0.5 1.7 0.3 0.4 0.8 0.5 1.3 1.2 0.8 0.7 1.7 1.0 1.6 1.2 0.2 0.8 0.1 0.1 1.4 1.6 1.4 0.4 68.2 0.9 0.6 0.9 0.7 1.2 0.3 1.1 7.2 1.4 0.2 1.5 0.2 0.5 0.2 0.4 0.6 0.3 2.4 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 4.5 0.1 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.1 0.2 0.1 4.1 0.1 0.0 0.1 19.4 0.0 0.0 0.1 0.0 0.1 0.6 0.1 0.0 0.6 1.0 0.3 0.0 0.5 0.1 0.0 0.1 0.1 0.1 0.6 0.0 0.2 0.2 0.1 0.0 0.1 0.1 0.0 0.1 0.0 1.9 0.1 0.1 0.3 0.1 0.2 0.0 0.6 0.1 0.2 0.1 4.0 3.3 0.8 0.7 1.7 0.5 0.6 0.6 0.5 2.5 1.1 0.6 0.7 2.7 1.3 12.1 0.9 0.4 3.5 1.2 1.4 2.2 1.7 1.3 1.2 1.6 1.2 1.6 1.1 1.5 2.4 2.2 0.0 0.5 0.3 1.9 0.9 1.2 0.0 0.6 17.0 2.2 2.0 2.0 2.8 0.0 5.5 141.8 0.1 0.9 0.4 0.0 1.6 0.4 3.8 0.6 3.6 0.0 0.0 0.2 1.5 0.2 0.7 2.6 2.8 0.0 0.1 3.9 0.2 3.9 13.5 0.3 0.7 0.0 9.5 1.9 0.2 0.3 1.9 1.8 2.8 0.3 28.9 5.2 0.0 0.4 1.7 0.1 0.0 1.5 1.5 0.1 1.2 0.7 254.4 0.0 4.8 0.6 0.0 0.3 0.2 0.3 0.8 1.4 0.0 0.2 1.0 CALHM6 "C6orf187, dJ93H18.5, FAM26F, INAM, OTTHUMP00000017061, OTTHUMP00000017062, RP1-93H18.5" ENSG00000188820 "Calcium homeostasis modulator family member 6" Q5R3K3 6 116461370-116463771 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 136.6" "Cell type enriched" "Detected in some" 5 "Hofbauer cells: 138.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 724.6;non-classical monocyte: 861.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 28.0;Karpas-707: 45.1;RPMI-8226: 159.8;U-937: 59.7" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (1.14e-2)" "unprognostic (2.31e-2)" "unprognostic (6.46e-3)" "unprognostic (7.15e-3)" "unprognostic (9.53e-3)" "unprognostic (4.10e-2)" "unprognostic (2.69e-1)" "unprognostic (1.68e-1)" "unprognostic (8.19e-2)" "unprognostic (1.24e-1)" "unprognostic (4.19e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (9.31e-10)" "unprognostic (1.69e-1)" "unprognostic (2.12e-2)" "unprognostic (3.85e-3)" "unprognostic (9.25e-3)" 7.4 7.3 4.9 60.2 5.2 41.4 10.0 4.5 6.6 4.3 5.0 10.4 12.2 2.4 3.6 4.1 4.1 7.2 4.3 4.7 5.2 4.1 24.7 10.8 73.0 8.1 4.7 4.5 1.8 1.7 4.8 12.5 5.3 5.4 7.0 1.1 5.7 3.0 1.6 1.9 20.9 11.8 5.6 136.6 7.9 8.2 5.3 14.0 2.4 2.6 23.1 11.4 3.0 5.4 6.4 0.0 0.6 0.4 0.5 2.0 11.7 0.2 1.3 2.0 1.3 0.0 1.0 0.2 3.5 1.5 0.0 0.0 0.3 0.2 4.2 0.7 0.4 28.0 0.0 0.0 2.8 0.1 0.1 2.2 0.0 0.2 0.2 0.5 0.7 0.0 0.0 45.1 5.5 0.0 2.7 4.8 3.6 0.0 0.0 2.4 0.0 159.8 2.2 0.3 2.7 0.1 14.9 0.1 11.7 1.6 0.2 7.3 0.1 0.0 0.2 0.1 0.9 11.4 0.2 0.0 0.3 59.7 3.9 22.0 205.7 50.1 16.6 724.6 16.6 231.8 23.0 15.5 193.8 308.9 28.9 15.2 115.8 27.4 861.9 86.5 2.7 175.6 4.9 5.2 4.5 6.6 4.7 5.2 8.1 4.7 5.3 5.6 5.3 5.4 0.6 0.0 1.7 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.8 3.2 0.0 0.0 0.0 0.0 0.0 1.7 2.7 0.0 0.0 0.6 0.0 0.2 0.3 0.8 0.0 0.0 0.0 10.0 9.0 0.7 0.0 0.1 0.0 1.4 0.0 0.0 138.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.0 10.3 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 2.2 1.2 1.8 0.0 0.0 CAMK4 "CaMK-GR, CaMKIV" ENSG00000152495 "Calcium/calmodulin dependent protein kinase IV" Q16566 5 111223653-111494886 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Inflammatory response" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 70.4;lymphoid tissue: 55.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 70.9;Early spermatids: 306.2;Excitatory neurons: 212.2;Inhibitory neurons: 131.8;Late spermatids: 108.4;Oligodendrocyte precursor cells: 133.2;T-cells: 83.3" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 6 "basal ganglia: 30.6;cerebellum: 70.4" "Group enriched" "Detected in many" 4 "MAIT T-cell: 24.3;memory CD4 T-cell: 17.3;memory CD8 T-cell: 13.5;naive CD4 T-cell: 33.1;naive CD8 T-cell: 18.5;T-reg: 21.3" "Lineage enriched" "Detected in many" 23 "T-cells: 33.1" "Cell line enhanced" "Detected in many" "HDLM-2: 88.9;JURKAT: 61.3;MOLT-4: 27.9;SH-SY5Y: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004347, HPA011753, HPA017206" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Nucleoplasm, Nucleoli fibrillar center" "CAB004347: AB_626793, HPA011753: AB_1845950, HPA017206: AB_1845949" "unprognostic (2.99e-5)" "unprognostic (7.19e-2)" "unprognostic (3.43e-3)" "unprognostic (5.11e-2)" "unprognostic (4.75e-3)" "unprognostic (3.48e-2)" "unprognostic (7.66e-4)" "unprognostic (7.22e-3)" "unprognostic (2.49e-1)" "unprognostic (2.92e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (2.23e-5)" "unprognostic (2.42e-2)" "unprognostic (3.01e-2)" "unprognostic (1.66e-1)" "unprognostic (9.99e-3)" 0.4 3.8 5.0 4.4 30.6 3.1 0.4 70.4 8.2 0.9 0.0 1.3 1.4 0.6 0.3 0.7 0.3 1.5 0.1 7.6 0.0 0.7 1.4 1.1 8.1 0.0 0.4 0.6 0.4 0.0 0.6 0.2 1.4 3.4 1.4 4.7 0.4 1.4 0.1 0.1 2.3 0.8 0.0 2.6 1.5 9.4 0.8 55.4 0.2 0.0 5.2 1.7 0.4 0.0 0.0 0.0 3.1 2.1 0.6 2.3 0.0 0.8 6.8 8.0 7.8 0.0 0.1 0.0 4.0 0.4 5.4 0.3 6.8 0.8 5.8 88.9 5.2 1.3 2.8 0.0 0.2 0.6 0.3 0.3 0.0 16.8 1.7 4.9 1.4 61.3 0.0 3.3 0.4 0.0 27.9 0.0 4.1 0.0 0.2 4.0 5.0 0.2 2.9 0.1 18.8 33.5 1.2 0.0 5.6 0.2 0.1 0.5 0.1 16.3 9.5 0.1 14.7 2.6 0.3 0.0 8.0 0.0 6.3 0.1 0.0 0.0 4.8 0.0 24.3 1.3 17.3 13.5 0.0 0.3 33.1 18.5 0.9 1.4 0.0 0.1 21.3 5.5 5.0 30.6 70.4 8.2 7.6 0.0 0.0 0.4 1.4 0.0 0.8 0.0 1.8 0.0 1.1 57.8 9.4 1.1 0.3 1.3 8.6 70.9 0.6 0.6 5.3 0.0 0.0 0.0 0.0 0.1 3.1 0.1 0.0 0.1 306.2 0.2 1.6 1.1 0.0 0.0 212.2 0.0 0.2 4.6 3.6 0.4 4.5 0.3 0.7 0.3 0.2 0.0 131.8 0.8 0.0 1.3 2.1 108.4 4.1 2.0 0.0 12.2 2.7 2.8 1.0 133.2 5.4 1.2 0.0 1.5 11.5 0.5 0.0 0.1 0.1 4.3 0.0 0.6 3.8 30.3 6.2 2.4 1.0 0.0 83.3 0.1 0.0 0.3 CAMKK1 "CAMKKA, DKFZp761M0423, MGC34095" ENSG00000004660 "Calcium/calmodulin dependent protein kinase kinase 1" Q8N5S9 17 3860315-3894891 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 41.9;Excitatory neurons: 52.7;Rod photoreceptor cells: 25.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 21.5;basal ganglia: 24.2;cerebral cortex: 54.4;hippocampal formation: 24.8;white matter: 31.9" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 28.3;U-87 MG: 27.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009111, HPA028062" Approved Supported Cytosol No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB009111: AB_2068406, HPA028062: AB_1845954" "unprognostic (1.39e-2)" "unprognostic (2.13e-1)" "unprognostic (8.66e-3)" "unprognostic (4.40e-3)" "unprognostic (2.94e-3)" "unprognostic (4.79e-2)" "unprognostic (1.98e-1)" "unprognostic (4.47e-3)" "unprognostic (8.23e-2)" "unprognostic (1.03e-2)" "prognostic favorable (2.65e-4)" "unprognostic (1.98e-1)" "unprognostic (1.59e-1)" "unprognostic (7.19e-2)" "unprognostic (8.70e-2)" "unprognostic (8.36e-2)" "unprognostic (3.10e-1)" 6.0 10.7 21.5 5.2 24.2 4.1 5.4 5.6 54.4 12.7 0.0 10.2 2.9 13.1 4.8 6.8 7.0 3.6 5.7 24.8 0.8 3.6 1.0 5.0 2.6 6.0 1.9 8.1 12.7 4.1 24.4 2.0 6.6 8.2 2.7 12.0 29.9 10.4 3.4 15.9 6.9 5.8 0.6 9.6 4.2 10.1 5.0 5.1 7.6 1.6 2.3 16.1 13.8 31.9 7.0 11.8 1.2 5.9 4.1 7.2 0.4 4.7 5.1 4.4 2.0 4.3 2.1 4.2 5.0 9.1 4.6 20.3 3.2 5.8 2.7 0.1 10.7 4.8 28.3 1.6 4.2 0.7 3.6 5.5 4.9 8.4 2.8 3.8 2.0 6.0 3.8 0.2 2.2 1.9 6.0 2.7 1.3 10.1 11.0 3.0 5.1 4.8 4.8 4.4 6.7 3.8 1.8 13.9 3.1 0.7 5.3 1.6 2.8 7.6 10.2 9.9 4.0 0.5 0.3 0.1 27.9 4.0 1.0 0.0 0.9 1.9 0.2 2.0 0.5 0.0 0.3 0.2 0.8 0.0 0.3 0.1 2.7 0.0 2.1 0.4 0.0 0.7 21.5 24.2 5.6 54.4 24.8 0.8 6.0 1.9 6.6 0.6 5.0 31.9 5.5 6.4 12.5 8.1 7.0 3.7 2.1 1.5 1.8 41.9 2.5 1.3 6.3 0.0 3.3 1.8 16.7 0.3 3.4 1.7 0.0 0.4 0.1 1.7 7.8 5.6 4.2 0.4 52.7 1.6 0.1 5.5 0.5 1.6 17.1 0.9 2.9 0.6 4.3 8.4 13.9 1.3 2.0 3.2 3.3 1.3 1.2 6.9 8.8 9.4 0.8 4.7 2.1 4.0 3.5 0.6 0.6 1.2 2.2 2.2 0.2 0.3 1.5 25.1 0.0 2.0 1.7 0.1 1.1 4.1 5.4 0.3 2.9 1.2 2.1 1.1 CAPN6 "CalpM, CANPX, CAPNX" ENSG00000077274 "Calpain 6" Q9Y6Q1 X 111245099-111270483 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "epididymis: 212.7;placenta: 83.1;seminal vesicle: 72.4" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 198.5;Syncytiotrophoblasts: 140.5" "Cancer enhanced" "Detected in many" "endometrial cancer: 25.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HDLM-2: 10.8;NTERA-2: 16.3;SuSa: 14.3" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 9.6" HPA040259 Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 5: NTERA-2 - Transcription" "Cluster 38: Extravillous trophoblasts - Unknown function" "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA040259: " "unprognostic (1.27e-3)" "unprognostic (2.04e-1)" "unprognostic (2.69e-2)" "unprognostic (5.77e-3)" "unprognostic (2.07e-1)" "unprognostic (9.93e-2)" "unprognostic (8.39e-3)" "unprognostic (1.06e-1)" "unprognostic (2.08e-1)" "unprognostic (9.45e-3)" "unprognostic (5.12e-1)" "unprognostic (6.25e-2)" "unprognostic (7.67e-2)" "unprognostic (6.50e-2)" "unprognostic (5.02e-3)" "unprognostic (2.66e-1)" "unprognostic (6.30e-2)" 2.1 0.0 0.0 7.2 0.0 0.0 12.7 0.0 0.0 11.9 0.0 5.6 1.8 22.5 212.7 2.3 3.2 8.4 0.3 0.0 0.0 11.5 0.3 0.5 2.8 0.0 0.0 2.6 7.5 0.1 0.2 83.1 0.0 10.6 8.6 0.0 14.1 72.4 3.0 1.0 1.7 8.2 0.0 1.7 12.9 2.0 0.0 1.8 1.5 9.0 4.7 3.8 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 16.3 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.1 0.3 0.4 0.3 0.0 14.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 1.1 0.0 1.2 0.0 0.6 2.0 0.3 7.2 0.0 7.3 0.0 39.9 0.1 0.1 3.9 8.3 0.0 18.0 4.3 0.4 0.0 0.0 0.0 0.7 198.5 12.9 6.6 40.1 0.0 0.0 0.0 0.0 7.6 0.0 0.1 1.2 0.0 0.0 0.3 0.5 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 22.2 0.1 0.4 0.0 0.2 0.0 0.0 0.0 1.0 0.5 0.1 0.1 0.9 0.0 140.5 0.3 0.9 0.5 0.3 CAPN7 PalBH ENSG00000131375 "Calpain 7" Q9Y6W3 3 15206152-15252916 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004745, HPA046617" Uncertain Approved Centrosome,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol Centrosome "HPA004745: , HPA046617: AB_2679721" "unprognostic (2.70e-2)" "unprognostic (2.79e-1)" "prognostic favorable (4.85e-5)" "unprognostic (1.85e-1)" "unprognostic (1.69e-2)" "unprognostic (1.41e-2)" "unprognostic (2.22e-3)" "unprognostic (2.72e-1)" "unprognostic (1.42e-1)" "unprognostic (2.76e-1)" "unprognostic (1.39e-1)" "unprognostic (5.29e-2)" "unprognostic (1.12e-3)" "unprognostic (3.24e-2)" "unprognostic (7.84e-2)" "unprognostic (5.66e-2)" "unprognostic (1.05e-2)" 13.9 11.9 4.6 11.6 5.9 13.2 16.6 12.5 5.4 16.9 9.3 12.1 12.9 16.1 14.9 11.4 14.4 11.1 11.6 4.1 8.1 15.2 19.1 12.1 14.3 5.9 5.7 19.8 15.3 20.1 9.2 12.9 5.5 14.1 12.2 28.5 13.9 12.7 25.3 11.6 13.6 13.8 6.0 11.4 14.0 12.1 6.8 16.9 23.5 16.5 15.7 10.2 9.8 9.7 14.3 18.5 15.1 9.5 26.0 20.1 51.4 18.1 20.8 22.1 16.7 13.3 10.0 24.6 12.3 20.7 13.6 9.7 22.5 23.3 19.0 23.7 17.5 30.8 24.8 17.7 19.3 25.1 15.0 13.9 33.2 28.7 14.1 20.9 15.9 23.3 30.3 25.1 21.6 20.8 17.9 10.5 14.5 20.7 17.7 10.2 25.1 17.1 16.4 25.8 12.2 15.8 29.5 15.7 20.8 19.2 27.9 25.8 14.4 19.8 14.9 25.9 21.4 17.2 37.1 12.4 18.1 18.0 17.5 4.6 3.0 5.1 3.3 2.5 5.3 3.5 3.6 2.8 2.9 3.1 4.9 4.6 1.8 3.6 4.4 2.4 3.0 3.0 4.6 5.9 12.5 5.4 4.1 8.1 5.9 5.7 5.5 6.0 6.8 9.7 15.8 12.8 23.6 44.1 35.0 21.4 13.5 10.6 47.3 42.7 20.3 16.0 33.2 8.6 20.6 1.8 56.3 21.2 21.7 11.2 9.8 12.6 15.5 32.2 31.5 19.0 20.9 14.9 60.2 16.9 12.6 27.6 30.1 29.9 15.8 28.9 14.6 20.8 12.2 55.5 65.8 11.3 4.1 11.9 23.0 14.8 24.8 20.9 21.4 49.6 18.4 31.2 10.3 73.9 86.0 13.0 6.9 26.4 52.8 20.0 16.7 15.2 34.9 98.1 39.5 31.5 24.8 26.8 17.8 29.7 23.2 26.1 34.2 21.1 11.8 14.3 CAV1 CAV ENSG00000105974 "Caveolin 1" Q03135 7 116524994-116561179 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Cancer-related genes, Congenital generalized lipodystrophy, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 2160.5;Alveolar cells type 1: 3557.7;Basal keratinocytes: 1375.3;Endothelial cells: 1024.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "basophil: 14.6;memory B-cell: 5.1" "Group enriched" "Detected in many" 57 "B-cells: 5.1;granulocytes: 14.6" "Cell line enhanced" "Detected in many" "ASC TERT1: 2140.5;BJ hTERT+: 2371.6;HBEC3-KT: 2333.7;LHCN-M2: 2372.1;U-138 MG: 1894.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 122.1" "CAB003791, HPA049326" Enhanced Supported "Golgi apparatus" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "CAB003791: AB_562068, HPA049326: AB_2680714" "unprognostic (5.98e-2)" "unprognostic (1.35e-3)" "unprognostic (3.35e-1)" "unprognostic (5.37e-2)" "unprognostic (4.62e-3)" "unprognostic (2.35e-3)" "unprognostic (8.07e-2)" "prognostic unfavorable (7.17e-5)" "unprognostic (1.31e-1)" "unprognostic (2.25e-1)" "unprognostic (1.79e-3)" "unprognostic (7.92e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.65e-3)" "unprognostic (2.72e-1)" "unprognostic (7.40e-2)" "unprognostic (6.14e-3)" 621.1 17.4 12.7 44.7 15.3 0.6 284.5 14.3 21.6 267.0 11.8 298.8 32.3 190.9 72.5 135.1 152.5 148.2 276.5 12.2 13.9 18.4 26.6 592.0 30.3 15.1 13.4 137.4 24.6 21.4 6.8 449.2 14.6 110.3 93.6 31.4 58.0 175.5 102.9 104.9 89.4 274.2 14.3 199.1 120.8 25.8 16.1 25.2 168.4 184.6 20.3 202.0 124.1 16.2 458.7 344.3 9.5 3.7 1406.6 2140.5 20.6 1055.8 2371.6 566.0 591.2 3.0 652.4 0.1 365.8 1228.5 494.8 828.2 2.2 2333.7 840.3 36.0 19.5 0.4 128.7 0.3 196.9 0.1 2.1 736.9 481.6 805.7 536.0 539.0 1749.9 0.2 0.3 23.4 2372.1 45.2 0.5 0.8 33.7 1.2 173.9 5.2 25.2 251.0 317.0 2.0 1.0 0.6 328.3 20.1 52.3 137.8 1.6 3.9 1349.3 1894.8 212.4 730.6 298.9 96.8 15.8 1.9 758.4 0.9 701.0 14.6 0.0 0.0 0.0 0.0 0.0 5.1 0.1 0.1 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.8 12.7 15.3 14.3 21.6 12.2 13.9 15.1 13.4 14.6 14.3 16.1 16.2 2160.5 3557.7 123.0 0.0 15.8 1375.3 392.0 534.8 316.4 8.3 17.9 190.8 286.6 107.2 342.0 7.3 2.1 64.3 7.0 0.3 5.9 76.8 2.6 17.5 102.3 1024.0 1.8 16.0 0.4 0.7 449.5 326.8 1.5 21.3 13.9 6.3 450.5 5.2 15.0 0.0 0.5 7.0 20.3 11.0 187.1 13.4 377.2 10.7 439.4 19.7 3.7 249.0 0.0 1.0 1.3 43.1 0.1 565.4 56.2 512.7 0.7 0.3 30.6 7.7 558.8 152.4 751.4 2.1 5.7 39.4 610.9 117.0 16.7 59.7 2.4 93.3 CAVIN2 "cavin-2, PS-p68, SDPR, SDR" ENSG00000168497 "Caveolae associated protein 2" O95810 2 191834310-191847088 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Adipocytes: 1296.7;Alveolar cells type 1: 413.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "basophil: 49.0;neutrophil: 24.3" "Lineage enriched" "Detected in many" 16 "granulocytes: 49.0" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 162.3;HEL: 119.8;HUVEC TERT2: 362.3;LHCN-M2: 561.1;TIME: 148.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039325, HPA062122" Enhanced Enhanced "Plasma membrane,Cytosol" Yes No 88000000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA039325: AB_10805473, HPA062122: AB_2684688" "unprognostic (6.85e-3)" "unprognostic (1.37e-1)" "unprognostic (1.24e-1)" "unprognostic (4.47e-2)" "unprognostic (2.83e-1)" "unprognostic (1.46e-1)" "unprognostic (3.19e-2)" "unprognostic (6.14e-2)" "unprognostic (8.50e-2)" "unprognostic (1.38e-1)" "unprognostic (4.83e-2)" "unprognostic (2.90e-1)" "prognostic favorable (8.45e-5)" "prognostic unfavorable (3.69e-4)" "unprognostic (1.03e-1)" "unprognostic (1.33e-1)" "unprognostic (4.39e-3)" 164.9 25.1 17.9 13.0 20.1 6.5 60.9 16.9 20.2 56.8 13.1 69.4 11.5 38.9 13.2 48.2 53.9 51.8 96.7 15.1 16.5 25.9 31.2 93.9 15.3 19.5 17.3 53.0 22.5 12.9 7.1 34.0 19.5 30.2 24.9 1.1 7.1 30.0 32.3 6.9 21.1 58.1 15.9 111.9 15.0 4.3 22.3 4.1 78.3 59.9 5.6 42.7 19.5 17.0 0.0 20.2 6.8 0.1 1.0 3.4 0.1 4.1 3.5 0.8 1.5 0.0 0.0 0.1 24.8 162.3 0.0 3.4 0.0 31.8 2.3 0.1 0.0 119.8 1.4 45.6 43.6 0.0 0.0 8.4 20.5 3.4 9.6 2.2 362.3 0.0 43.9 0.0 561.1 0.0 0.0 0.1 0.1 0.0 1.0 0.0 32.3 0.2 41.7 0.0 0.0 0.1 0.0 0.0 0.0 9.1 0.0 0.1 148.9 0.0 12.4 7.4 0.0 0.0 0.0 0.1 0.0 1.0 0.0 49.0 2.4 1.2 0.2 0.8 0.3 0.1 0.0 0.0 2.3 0.3 0.2 0.0 24.3 1.3 1.5 3.1 0.5 121.3 17.9 20.1 16.9 20.2 15.1 16.5 19.5 17.3 19.5 15.9 22.3 17.0 1296.7 413.5 76.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 1.7 15.6 0.0 0.0 81.7 0.0 0.0 0.2 2.6 0.0 5.9 1.6 0.0 0.4 5.4 164.5 0.0 0.0 0.0 0.2 0.2 15.0 0.0 0.6 185.4 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.7 29.2 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.1 1.5 16.4 0.0 0.0 CBX2 "CDCA6, MGC10561" ENSG00000173894 "Chromobox 2" Q14781 17 79778148-79787983 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Sexual differentiation, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 7.3;testis: 12.8" "Cell type enhanced" "Detected in many" "Early spermatids: 32.5;Granulosa cells: 10.4;Late spermatids: 39.1;Spermatogonia: 14.3" "Cancer enhanced" "Detected in many" "testis cancer: 20.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "REH: 96.4;SK-BR-3: 134.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA023083 Approved Supported Nucleoplasm NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA023083: AB_2671063" "unprognostic (1.37e-2)" "unprognostic (1.19e-1)" "unprognostic (1.95e-1)" "unprognostic (3.80e-2)" "unprognostic (1.49e-1)" "unprognostic (9.72e-2)" "unprognostic (2.25e-11)" "unprognostic (1.05e-1)" "unprognostic (7.77e-2)" "unprognostic (6.34e-3)" "unprognostic (1.86e-3)" "unprognostic (1.66e-1)" "unprognostic (1.25e-8)" "unprognostic (1.34e-1)" "unprognostic (3.33e-2)" "unprognostic (2.37e-3)" "unprognostic (2.07e-1)" 1.4 0.3 1.1 0.7 0.9 2.2 1.2 0.8 0.9 1.3 0.5 0.5 0.4 1.2 1.8 4.2 1.0 0.6 2.3 0.8 0.7 1.6 0.4 1.2 1.3 1.0 0.9 2.1 1.3 0.5 0.2 2.2 1.1 0.6 0.2 0.5 0.9 0.5 0.7 2.1 0.6 0.7 0.8 1.6 0.5 12.8 1.0 7.3 0.5 1.1 1.3 1.0 1.6 1.0 7.5 20.5 37.0 67.4 0.4 0.5 13.2 2.7 1.2 1.3 2.4 21.2 1.7 29.7 5.8 0.3 4.7 3.8 43.0 1.2 0.9 4.3 23.3 1.5 24.0 14.2 1.4 9.0 6.1 0.7 2.6 0.7 1.7 1.6 7.5 31.3 20.8 2.3 1.4 31.3 47.3 22.1 36.8 10.3 23.4 96.4 27.7 18.0 1.5 10.5 45.1 69.8 11.7 134.7 8.0 17.6 24.5 13.4 5.4 13.1 38.4 4.0 5.3 8.7 4.8 18.3 0.5 24.1 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.9 0.8 0.9 0.8 0.7 1.0 0.9 1.1 0.8 1.0 1.0 5.3 0.0 0.0 0.3 0.1 1.0 0.3 0.4 0.0 1.0 0.6 1.8 2.5 0.0 0.3 1.8 2.1 0.4 2.9 0.4 1.9 3.6 32.5 0.9 1.8 8.6 0.0 5.9 0.1 0.9 1.4 0.8 1.1 1.8 0.0 10.4 3.6 1.1 1.2 0.0 0.0 0.8 0.0 0.6 0.9 39.1 0.6 0.5 3.6 0.0 0.8 4.3 0.0 0.0 0.3 1.1 0.0 0.7 0.5 0.7 0.0 0.8 0.1 0.4 0.0 0.3 1.0 1.6 14.3 4.1 1.4 0.3 1.2 0.9 0.5 0.9 CCDC102B "ACY1L, AN, C18orf14, FLJ23594, HsT1731" ENSG00000150636 "Coiled-coil domain containing 102B" Q68D86 18 68715209-69055189 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 28.4" "Cell type enhanced" "Detected in many" "Astrocytes: 72.8;Early spermatids: 138.2;Excitatory neurons: 80.8;Late spermatids: 83.3;Oligodendrocytes: 90.1;Sertoli cells: 78.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 9.1" "Lineage enriched" "Detected in many" 5 "dendritic cells: 9.1" "Cell line enhanced" "Detected in many" "ASC TERT1: 14.2;BJ hTERT+: 29.0;fHDF/TERT166: 26.2;HSkMC: 15.4;Karpas-707: 10.2" "HPA040623, HPA048194" Approved Approved Mitochondria,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria Cytosol "HPA040623: AB_10805715, HPA048194: AB_2680309" "unprognostic (3.92e-2)" "unprognostic (1.62e-1)" "unprognostic (5.58e-2)" "unprognostic (9.50e-3)" "unprognostic (7.13e-2)" "unprognostic (3.50e-1)" "unprognostic (7.87e-3)" "unprognostic (1.36e-1)" "unprognostic (5.59e-2)" "unprognostic (8.62e-3)" "unprognostic (1.95e-1)" "unprognostic (6.04e-2)" "prognostic unfavorable (2.90e-6)" "unprognostic (2.21e-2)" "unprognostic (2.12e-2)" "unprognostic (8.00e-3)" "unprognostic (3.13e-3)" 7.1 2.9 1.5 3.7 1.8 0.7 2.7 0.6 3.5 2.8 0.0 3.8 1.5 1.7 1.1 3.4 1.8 13.6 3.2 1.3 2.0 4.3 1.7 14.3 8.6 2.6 1.6 0.9 1.5 2.6 0.9 28.4 3.1 1.2 4.5 2.2 1.3 1.3 0.6 1.0 2.6 3.7 2.0 2.2 3.6 2.0 2.3 1.5 5.2 1.1 2.0 10.6 1.5 3.6 0.0 0.0 4.0 0.3 3.6 14.2 0.2 0.8 29.0 0.3 0.5 0.1 0.4 0.1 0.6 26.2 0.5 0.4 0.1 0.2 0.4 1.2 0.4 0.8 0.0 1.3 7.0 0.1 0.4 15.4 0.6 0.4 3.5 0.6 0.2 2.0 0.0 10.2 2.4 0.0 0.6 0.3 0.8 0.2 0.5 1.3 0.2 0.5 0.1 0.0 1.7 1.5 0.1 0.0 0.1 1.6 0.3 1.3 4.0 0.6 0.2 0.2 0.3 4.4 0.3 0.8 2.1 1.7 2.5 0.0 0.1 0.3 1.0 0.2 0.9 0.5 0.6 0.8 0.2 0.6 1.8 1.1 0.0 1.0 0.2 9.1 0.3 0.3 1.5 1.8 0.6 3.5 1.3 2.0 2.6 1.6 3.1 2.0 2.3 3.6 11.5 0.0 2.2 72.8 4.4 0.6 0.8 0.8 0.6 6.4 2.7 2.9 10.0 0.0 2.1 3.7 6.2 0.8 12.4 0.4 5.9 0.7 138.2 2.9 6.7 6.8 0.0 3.0 80.8 1.8 0.6 15.3 0.0 1.1 2.5 5.7 8.6 0.8 3.2 6.7 33.6 0.2 0.0 1.9 1.8 83.3 32.3 3.3 0.0 44.0 2.1 11.9 7.2 36.2 90.1 0.2 2.6 9.1 2.2 0.4 0.3 5.3 1.5 13.4 78.9 3.8 37.3 1.9 5.7 0.7 0.6 0.3 3.8 3.7 0.4 0.6 CCDC170 "bA282P11.1, C6orf97, FLJ23305" ENSG00000120262 "Coiled-coil domain containing 170" Q8IYT3 6 151494017-151621193 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "fallopian tube: 33.4" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 236.6;Late spermatids: 82.6;Respiratory ciliated cells: 379.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 6.2" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "MCF7: 10.4;T-47d: 5.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027114, HPA027185" Enhanced Approved "Golgi apparatus,Cell Junctions" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" "Golgi apparatus" "Cell Junctions" "HPA027114: AB_2732435, HPA027185: AB_2672151" "unprognostic (7.46e-2)" "unprognostic (3.54e-2)" "unprognostic (6.93e-2)" "prognostic favorable (3.64e-4)" "unprognostic (2.13e-1)" "unprognostic (8.79e-3)" "unprognostic (2.74e-3)" "unprognostic (1.34e-1)" "unprognostic (1.77e-1)" "unprognostic (1.96e-1)" "unprognostic (2.36e-1)" "unprognostic (2.18e-2)" "unprognostic (3.56e-2)" "unprognostic (1.40e-2)" "unprognostic (3.93e-2)" "unprognostic (2.17e-1)" "unprognostic (5.21e-2)" 3.0 4.2 1.5 1.3 1.4 0.1 3.7 0.9 0.7 3.0 8.0 0.7 2.5 3.6 0.4 0.4 33.4 1.3 0.8 1.3 1.8 0.8 1.3 4.1 1.4 3.6 4.9 5.6 0.1 0.1 0.2 1.4 3.1 0.4 0.6 0.2 0.2 0.4 0.3 0.2 1.1 0.9 3.2 2.2 1.7 2.7 1.7 0.3 5.6 0.1 0.6 1.1 0.5 2.8 0.0 0.1 0.3 0.0 0.3 0.3 0.0 0.1 0.4 0.0 0.0 0.2 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.1 0.1 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.1 0.0 0.0 0.1 5.9 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 2.1 6.2 0.0 2.8 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.8 0.1 2.8 0.1 0.0 0.6 1.5 1.4 0.9 0.7 1.3 1.8 3.6 4.9 3.1 3.2 1.7 2.8 1.2 3.2 1.5 7.5 0.4 0.6 0.3 6.5 1.2 0.3 27.3 8.9 0.7 0.0 39.5 0.0 22.9 0.1 0.4 1.1 0.0 0.3 53.0 236.6 23.6 1.2 0.0 0.0 5.5 1.1 0.4 5.2 3.1 14.1 3.8 3.5 1.1 1.5 11.9 0.0 5.9 0.0 12.2 17.5 11.3 82.6 7.2 16.8 0.0 0.0 11.0 2.5 0.0 3.0 0.8 2.7 5.8 0.0 0.1 0.9 0.5 5.8 379.4 1.0 0.0 0.4 6.5 19.1 1.1 0.2 1.0 0.0 1.2 14.0 0.3 0.5 CCDC184 "C12orf68, LOC387856" ENSG00000177875 "Coiled-coil domain containing 184" Q52MB2 12 48183644-48185926 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.7" "Cell type enhanced" "Detected in many" "Early spermatids: 62.5;Late spermatids: 15.1;Sertoli cells: 46.0" "Cancer enhanced" "Detected in many" "glioma: 6.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.7;AF22: 6.3;hTERT-RPE1: 2.4;SH-SY5Y: 4.3;U-2 OS: 2.5;U-87 MG: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039947, HPA041715" Uncertain Approved Mitochondria,Cytosol No No "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "Mitochondria, Cytosol" "HPA039947: AB_2676764, HPA041715: AB_2677634" "unprognostic (2.02e-1)" "unprognostic (1.16e-2)" "unprognostic (6.97e-2)" "unprognostic (2.03e-1)" "unprognostic (1.61e-2)" "unprognostic (4.59e-1)" "unprognostic (1.33e-2)" "unprognostic (6.65e-2)" "unprognostic (9.79e-2)" "unprognostic (8.38e-2)" "unprognostic (1.03e-2)" "unprognostic (1.07e-1)" "unprognostic (5.87e-4)" "unprognostic (1.08e-2)" "unprognostic (2.39e-2)" "unprognostic (2.55e-1)" "unprognostic (2.36e-2)" 1.1 5.3 12.3 0.9 12.0 0.1 1.0 11.2 21.4 3.5 1.1 1.8 0.2 5.4 0.3 0.9 1.0 1.3 2.3 10.8 25.7 0.7 0.3 0.8 0.2 18.3 12.5 7.5 0.6 5.8 11.6 2.3 24.5 1.4 0.4 5.0 0.4 0.8 0.9 0.4 0.9 1.4 7.5 0.9 1.0 6.2 11.9 0.0 0.9 0.4 0.0 2.0 1.5 10.8 0.0 2.7 6.3 0.2 0.5 0.5 0.0 0.2 1.2 0.3 0.5 0.3 0.1 0.0 0.1 0.2 1.6 0.1 0.6 0.1 0.0 1.5 0.1 0.0 0.0 0.0 0.2 0.0 0.5 0.2 0.0 0.0 0.0 2.4 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 4.3 0.5 0.0 0.1 0.1 0.0 0.0 0.1 0.7 2.5 0.0 0.1 0.0 0.0 0.0 3.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 12.0 11.2 21.4 10.8 25.7 18.3 12.5 24.5 7.5 11.9 10.8 1.2 0.0 0.0 2.6 1.1 0.0 0.1 0.0 6.2 2.3 0.3 1.9 0.6 0.0 0.6 0.0 0.0 0.7 2.0 0.1 0.0 0.3 62.5 0.4 9.4 3.1 5.3 0.0 5.6 0.0 0.6 11.2 1.1 0.2 0.0 4.2 6.8 0.0 0.9 5.0 12.7 0.0 0.0 0.3 0.0 15.1 0.3 0.5 0.0 1.0 0.0 3.0 0.0 1.5 1.1 0.1 0.0 2.2 0.2 0.1 0.0 0.0 5.1 7.0 46.0 8.6 7.6 12.7 1.8 2.2 0.0 1.5 3.2 1.8 0.0 0.0 CCDC25 FLJ10853 ENSG00000147419 "Coiled-coil domain containing 25" Q86WR0 8 27733316-27772653 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023256 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Golgi apparatus" Cytosol "HPA023256: AB_2072067" "unprognostic (1.43e-1)" "unprognostic (5.48e-2)" "unprognostic (3.10e-3)" "unprognostic (1.60e-1)" "unprognostic (4.39e-1)" "unprognostic (6.62e-3)" "unprognostic (2.34e-1)" "unprognostic (2.48e-2)" "unprognostic (1.51e-1)" "unprognostic (8.49e-3)" "unprognostic (3.50e-1)" "unprognostic (2.69e-2)" "prognostic favorable (1.11e-7)" "unprognostic (3.93e-2)" "unprognostic (1.21e-1)" "unprognostic (1.18e-1)" "unprognostic (1.69e-1)" 14.0 20.9 10.1 11.8 11.4 4.9 17.4 10.5 17.1 10.1 7.3 14.3 35.5 10.4 14.3 14.2 12.9 11.9 12.2 9.9 11.3 22.5 32.3 8.8 14.0 11.1 10.5 10.8 16.3 18.3 7.5 10.6 11.5 11.6 15.7 11.1 13.5 12.0 28.4 10.3 30.8 10.3 11.3 10.5 20.0 10.9 11.9 11.4 18.8 15.2 14.2 11.7 9.4 13.0 50.1 27.9 25.8 24.7 22.8 33.0 17.2 41.0 39.5 24.7 24.0 11.2 17.9 53.6 27.7 20.9 21.2 23.1 23.6 40.0 35.5 20.3 16.4 66.9 23.1 19.3 36.9 23.8 20.8 37.1 25.9 27.1 37.6 28.7 54.0 33.7 32.2 24.6 27.8 19.2 55.3 19.9 37.9 49.4 14.8 18.7 44.4 28.8 32.3 26.7 15.1 41.7 27.5 21.0 42.8 19.0 24.0 13.1 44.6 22.5 33.4 38.9 21.7 24.5 33.8 19.5 35.0 30.8 23.8 20.3 8.9 6.6 15.2 12.6 17.8 19.8 19.6 16.1 11.6 15.5 18.3 19.3 3.2 14.3 13.4 18.1 23.2 10.4 10.1 11.4 10.5 17.1 9.9 11.3 11.1 10.5 11.5 11.3 11.9 13.0 47.5 25.6 38.9 12.4 34.8 21.4 39.6 46.5 55.2 42.6 57.3 61.6 62.5 60.1 44.5 53.3 12.5 77.6 31.2 61.6 109.5 76.9 183.1 46.8 51.0 54.2 26.5 46.7 30.5 134.6 56.0 49.3 63.2 33.3 63.9 39.3 55.0 144.5 44.7 55.5 21.9 58.6 46.8 33.5 27.2 162.9 47.2 27.4 37.4 12.2 44.4 60.2 35.0 12.1 17.7 83.7 51.1 47.4 40.7 55.2 182.1 128.6 53.7 38.9 46.0 44.4 49.1 91.1 59.6 56.7 22.3 42.4 38.7 88.1 71.2 36.0 CCDC69 "DKFZP434C171, FLJ13705" ENSG00000198624 "Coiled-coil domain containing 69" A6NI79 5 151181052-151224093 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 351.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 124.5;dendritic cells: 106.9;Granulosa cells: 138.2;NK-cells: 197.8;Plasma cells: 133.6;Theca cells: 132.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 129.2;Daudi: 199.9;U-266/70: 120.5;U-698: 119.1" "Region enhanced" "Detected in some" "cerebellum: 4.8" "Low region specificity" "Detected in all" "HPA043648, HPA052896" Uncertain Approved "Golgi apparatus,Plasma membrane,Actin filaments" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "Golgi apparatus, Actin filaments" "HPA043648: AB_10795877, HPA052896: AB_2681983" "prognostic favorable (3.21e-4)" "unprognostic (2.60e-2)" "unprognostic (1.28e-1)" "unprognostic (2.78e-2)" "unprognostic (5.62e-2)" "unprognostic (8.63e-3)" "unprognostic (3.07e-2)" "unprognostic (6.48e-2)" "unprognostic (2.00e-1)" "unprognostic (9.29e-2)" "unprognostic (3.85e-2)" "unprognostic (1.55e-2)" "unprognostic (3.67e-1)" "unprognostic (4.31e-2)" "unprognostic (3.69e-1)" "unprognostic (2.93e-1)" "unprognostic (2.01e-1)" 108.9 89.6 6.7 45.8 8.4 46.3 60.5 12.2 7.9 15.2 13.4 138.5 19.6 32.9 13.3 54.1 37.1 19.3 96.9 5.9 8.9 10.7 24.0 39.0 70.4 13.3 13.8 27.1 47.5 32.1 8.5 14.8 13.6 23.0 20.5 1.8 14.4 29.4 351.9 13.3 44.7 45.6 11.3 55.4 37.0 13.2 9.2 37.8 11.6 163.8 66.8 87.7 21.9 7.2 8.0 1.6 0.4 6.4 129.2 13.1 4.2 1.5 13.1 2.6 2.4 2.1 1.1 199.9 6.3 0.5 3.3 1.0 3.0 2.8 0.9 0.1 2.7 27.0 0.0 17.5 21.1 9.9 34.4 33.0 0.2 1.0 0.0 2.5 13.1 0.0 23.7 44.0 0.1 0.6 43.8 23.3 7.5 0.1 15.2 36.0 1.0 12.1 0.5 5.9 0.2 0.8 2.4 3.2 1.7 3.2 2.0 24.0 32.0 1.0 6.1 0.6 1.5 120.5 60.1 119.1 1.4 22.2 0.0 30.9 12.4 13.5 11.3 10.9 10.3 5.4 8.8 10.8 10.0 10.4 6.1 6.6 9.6 14.3 10.3 19.3 8.5 11.5 6.7 8.4 12.2 7.9 5.9 8.9 13.3 13.8 13.6 11.3 9.2 7.2 51.0 12.8 78.4 0.7 68.8 2.5 3.0 3.5 1.2 0.4 4.8 2.4 124.5 1.5 13.5 1.8 0.0 7.3 106.9 0.2 0.0 2.9 0.5 26.8 2.7 58.9 1.8 32.2 1.8 20.0 9.6 18.4 7.1 1.3 34.8 138.2 28.2 39.7 7.3 6.7 2.7 0.0 4.1 64.0 12.2 2.4 5.6 46.5 10.6 11.2 73.5 4.9 197.8 1.0 0.6 8.8 0.1 7.9 133.6 3.6 4.5 3.2 51.3 1.4 13.1 4.7 14.8 1.2 1.0 0.7 1.3 35.4 65.7 132.1 0.9 23.5 CCDC80 "CL2, DRO1, LINC01279, SSG1, TCONS_00006930, URB" ENSG00000091986 "Coiled-coil domain containing 80" Q76M96 3 112596797-112649530 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 450.8;Fibroblasts: 921.6;Late spermatids: 353.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 521.4;fHDF/TERT166: 1281.3;hTERT-RPE1: 2404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002266 Approved "Secreted to extracellular matrix" NA NA 510000 "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA002266: AB_1078423" "unprognostic (1.26e-1)" "unprognostic (1.89e-1)" "unprognostic (1.26e-2)" "unprognostic (3.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.50e-1)" "unprognostic (2.82e-1)" "unprognostic (2.53e-2)" "unprognostic (2.30e-3)" "unprognostic (1.99e-3)" "unprognostic (8.40e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (2.86e-5)" "unprognostic (5.97e-3)" "unprognostic (1.65e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.26e-4)" 244.9 15.0 6.4 83.5 6.9 1.1 218.3 9.6 8.6 305.3 24.4 74.5 8.7 276.5 76.8 92.4 82.2 234.0 218.8 6.8 10.2 17.7 6.6 74.0 18.5 12.2 11.4 62.2 28.7 12.4 10.8 26.0 9.3 67.8 73.4 9.4 34.7 78.7 13.4 79.1 25.1 360.3 11.1 34.8 47.5 42.7 9.2 17.1 87.5 34.9 30.8 194.4 131.8 13.5 26.1 11.0 127.6 5.8 521.4 411.2 6.9 359.0 108.5 118.6 171.8 2.9 2.1 1.2 13.5 1281.3 11.4 33.5 5.3 4.8 123.7 24.3 1.2 0.7 27.7 0.7 109.5 1.0 0.5 409.7 14.4 174.9 11.0 2404.9 27.8 0.6 0.4 1.0 352.7 0.5 0.3 0.7 31.6 0.7 4.2 0.3 14.0 0.6 3.3 0.5 0.4 2.5 53.5 2.3 1.8 23.0 2.1 1.0 141.7 345.6 56.6 66.6 160.1 1.6 0.8 1.2 102.4 0.7 56.8 0.9 0.3 0.2 0.3 0.1 0.3 0.4 0.3 0.3 0.1 0.6 0.4 0.4 0.3 0.3 0.2 0.7 0.2 0.0 6.4 6.9 9.6 8.6 6.8 10.2 12.2 11.4 9.3 11.1 9.2 13.5 104.5 6.4 15.9 13.1 1.5 60.9 4.2 44.7 26.7 1.1 5.9 59.7 22.5 10.0 62.7 5.5 0.0 57.9 1.0 0.3 1.9 23.7 450.8 95.4 93.2 43.9 0.0 0.0 1.0 1.2 101.5 921.6 16.8 18.4 1.3 44.3 53.6 0.9 9.4 0.0 0.3 0.8 30.5 2.2 121.5 353.6 77.0 9.7 144.1 3.7 2.0 101.4 0.0 0.0 0.0 13.5 0.0 34.6 5.8 3.6 0.0 0.1 112.4 2.5 19.7 177.7 198.4 6.9 4.9 11.9 51.7 27.9 9.0 23.0 0.1 1.9 CCDC93 FLJ10996 ENSG00000125633 "Coiled-coil domain containing 93" Q567U6 2 117915478-118014133 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054183 Approved Enhanced "Vesicles,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" Vesicles "Plasma membrane" "HPA054183: AB_2682408" "unprognostic (1.47e-1)" "unprognostic (6.55e-2)" "unprognostic (8.29e-2)" "unprognostic (1.02e-2)" "unprognostic (3.32e-2)" "unprognostic (2.47e-3)" "prognostic unfavorable (2.97e-6)" "unprognostic (2.51e-1)" "unprognostic (8.12e-2)" "unprognostic (8.99e-2)" "unprognostic (1.52e-3)" "unprognostic (8.56e-2)" "unprognostic (4.87e-1)" "unprognostic (1.79e-2)" "unprognostic (2.67e-1)" "prognostic unfavorable (9.66e-4)" "unprognostic (2.40e-2)" 10.2 14.5 9.3 10.4 8.5 21.7 9.6 9.6 12.7 9.1 15.0 11.3 11.9 8.2 9.8 7.4 9.3 7.1 21.3 8.4 9.4 9.8 7.8 11.8 10.3 9.7 9.0 13.3 13.0 15.9 16.1 8.1 10.3 7.6 10.6 26.0 9.1 8.4 12.9 11.0 12.8 8.1 8.4 12.1 9.1 12.1 11.5 10.1 11.9 10.3 10.1 8.6 8.1 8.5 18.7 8.1 22.0 19.4 31.2 21.3 18.5 21.8 14.2 14.0 14.3 17.7 11.7 15.9 14.5 17.1 24.9 15.8 12.8 11.2 18.1 20.8 13.0 20.1 15.5 23.9 13.7 22.1 22.0 14.6 11.5 21.9 25.9 19.4 15.0 18.9 11.1 11.0 15.8 8.1 14.0 23.8 9.9 13.4 13.0 17.6 17.2 10.7 11.5 19.6 17.4 10.3 14.2 10.6 15.1 19.6 8.9 13.5 21.2 23.9 20.0 20.4 15.3 14.3 16.0 24.7 13.8 16.1 14.2 2.9 1.6 1.8 2.1 2.1 2.0 1.6 1.5 1.8 1.2 1.4 2.0 1.7 1.7 1.7 1.3 0.5 0.7 1.0 9.3 8.5 9.6 12.7 8.4 9.4 9.7 9.0 10.3 8.4 11.5 8.5 17.4 19.2 28.2 61.0 28.6 17.6 14.6 11.2 9.6 32.0 12.4 10.0 43.0 7.2 17.5 1.8 47.9 12.6 31.9 21.5 9.8 24.0 4.5 14.9 15.2 16.5 16.7 9.9 57.1 16.7 8.5 14.7 11.7 17.0 15.2 25.1 12.8 6.0 15.2 20.2 60.6 11.4 10.2 16.3 15.9 10.6 13.7 19.9 3.6 32.8 19.9 13.8 20.6 53.3 37.9 32.0 11.9 14.3 19.4 13.9 17.1 9.4 16.3 36.0 6.6 21.4 15.0 46.0 31.1 10.1 16.1 12.9 24.3 12.8 14.0 15.0 CCDC97 "FLJ40267, MGC20255" ENSG00000142039 "Coiled-coil domain containing 97" Q96F63 19 41310172-41324873 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043320, HPA043572" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Plasma membrane, Cytosol" "HPA043320: AB_10964344, HPA043572: AB_10962488" "unprognostic (9.25e-3)" "unprognostic (7.26e-2)" "unprognostic (1.68e-1)" "unprognostic (5.10e-2)" "unprognostic (1.04e-1)" "unprognostic (1.51e-2)" "prognostic unfavorable (1.09e-4)" "unprognostic (8.40e-2)" "unprognostic (1.91e-2)" "unprognostic (2.44e-1)" "unprognostic (5.93e-3)" "unprognostic (4.51e-2)" "unprognostic (2.16e-1)" "unprognostic (2.96e-1)" "unprognostic (4.08e-1)" "unprognostic (7.92e-2)" "unprognostic (1.65e-2)" 14.6 12.9 19.0 17.8 21.3 23.0 14.3 17.7 17.7 20.3 14.4 14.0 14.2 17.3 23.4 20.2 21.9 12.3 15.6 16.5 18.2 12.0 11.8 14.3 23.8 23.5 20.2 24.0 17.7 15.8 13.7 10.5 19.9 16.2 11.2 10.7 18.0 14.6 30.6 20.2 16.6 14.2 18.1 20.0 15.7 32.1 20.4 21.9 16.3 20.5 22.2 14.8 17.2 20.5 25.2 54.1 28.2 32.9 36.2 28.7 20.3 16.6 13.4 25.7 21.9 32.4 23.6 23.9 17.4 13.9 17.3 16.7 38.8 33.1 19.5 44.1 37.6 21.9 25.5 21.5 27.5 36.6 45.3 28.1 41.7 30.0 25.0 21.1 18.0 25.8 28.5 44.4 24.9 18.3 33.6 8.9 13.2 30.5 19.3 37.5 22.4 17.5 23.7 47.3 25.1 22.2 37.0 40.3 16.5 18.6 27.5 27.6 21.6 22.1 22.0 11.5 27.8 45.3 42.2 22.7 21.0 26.7 30.0 9.4 7.2 8.5 12.0 7.6 13.4 9.1 8.1 8.7 5.8 10.0 8.7 7.8 11.9 10.4 12.6 6.3 7.2 8.1 19.0 21.3 17.7 17.7 16.5 18.2 23.5 20.2 19.9 18.1 20.4 20.5 7.3 12.8 6.7 5.2 22.3 4.6 11.4 11.3 6.2 11.8 11.2 8.8 6.7 7.2 8.9 9.2 12.5 11.1 23.9 13.5 7.9 13.1 3.7 9.3 8.6 8.4 11.5 7.8 4.1 26.1 4.5 10.0 15.3 9.8 16.5 11.2 9.7 6.5 15.3 10.1 4.7 12.1 18.3 10.0 7.9 8.4 12.8 12.3 1.8 3.7 16.1 7.1 25.7 1.0 6.6 20.5 5.9 11.3 18.6 10.0 16.7 9.3 12.2 8.5 0.0 13.1 8.5 22.5 12.9 10.8 5.8 18.3 20.1 7.2 10.7 13.3 CCL14 "CKb1, HCC-1, HCC-3, MCIF, NCC-2, SCYA14, SCYL2" ENSG00000276409 "C-C motif chemokine ligand 14" Q16627 17 35983288-35987004 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 632.7" "Cell type enriched" "Detected in many" 5 "Hepatic stellate cells: 1156.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 41 "HUVEC TERT2: 92.1" "Low region specificity" "Detected in all" "CAB004423, HPA030268" Uncertain "Secreted to blood" NA NA 5200000 37000000 "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004423: AB_627716, HPA030268: AB_10603782" "unprognostic (4.13e-2)" "unprognostic (5.85e-2)" "unprognostic (4.86e-2)" "unprognostic (3.55e-3)" "unprognostic (2.50e-1)" "unprognostic (1.99e-2)" "unprognostic (8.79e-5)" "unprognostic (1.44e-1)" "unprognostic (1.53e-1)" "unprognostic (8.10e-2)" "unprognostic (6.33e-3)" "unprognostic (3.00e-2)" "unprognostic (7.27e-3)" "unprognostic (1.36e-2)" "unprognostic (3.95e-1)" "unprognostic (3.52e-1)" "unprognostic (1.14e-1)" 411.9 102.7 0.4 6.4 0.3 3.3 400.7 0.2 1.7 192.0 2.8 66.6 2.9 198.0 59.3 62.0 233.5 69.3 98.6 0.3 0.3 69.2 82.6 66.4 49.0 0.5 0.3 44.1 22.6 12.4 39.5 0.9 0.7 97.4 9.8 0.0 61.9 49.5 55.9 93.3 50.5 94.3 0.4 632.7 67.5 16.0 0.4 34.4 123.9 24.5 28.2 116.8 177.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 92.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 1.7 0.3 0.3 0.5 0.3 0.7 0.4 0.4 0.3 136.5 0.0 8.2 0.0 2.2 1.9 0.1 0.0 3.4 0.0 0.6 1.1 0.2 18.6 0.6 0.0 0.0 0.0 0.1 2.0 0.0 0.0 24.2 0.4 0.3 203.8 0.0 26.7 0.0 0.0 0.0 9.4 0.0 0.2 1.3 0.0 1156.5 11.0 0.3 0.0 0.0 1.0 0.0 58.8 3.1 63.8 1.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.2 2.3 1.1 2.6 0.0 0.0 0.3 2.3 0.0 0.0 2.0 1.4 0.0 1.8 0.1 0.6 0.2 CCL23 "Ckb-8, CKb8, MIP-3, MPIF-1, SCYA23" ENSG00000274736 "C-C motif chemokine ligand 23" P55773 17 36013056-36017972 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "Hepatic stellate cells: 243.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 163 "eosinophil: 183.7" "Lineage enriched" "Detected in many" 163 "granulocytes: 183.7" "Group enriched" "Detected in some" 4 "HEL: 17.6;THP-1: 37.4" HPA042015 Uncertain "Secreted to blood" NA NA 937000 130000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA042015: AB_10794039" "unprognostic (1.65e-3)" "unprognostic (1.43e-2)" "unprognostic (1.04e-1)" "unprognostic (9.50e-2)" "unprognostic (3.59e-2)" "unprognostic (2.39e-1)" "unprognostic (1.20e-4)" "unprognostic (2.17e-1)" "unprognostic (6.49e-2)" "unprognostic (1.08e-2)" "unprognostic (7.05e-2)" "unprognostic (6.93e-2)" "unprognostic (1.35e-3)" "unprognostic (2.18e-1)" "unprognostic (2.76e-1)" "unprognostic (1.20e-2)" "unprognostic (1.95e-1)" 7.9 6.7 0.0 7.0 0.0 3.7 7.3 0.0 0.2 18.5 0.1 4.3 0.2 14.8 1.6 4.7 11.9 3.3 0.7 0.0 0.0 12.0 7.5 21.4 1.6 0.0 0.0 2.9 1.0 0.0 0.3 0.3 0.0 8.6 8.7 0.0 3.5 0.3 0.5 3.6 9.3 10.8 0.0 14.1 3.3 0.6 0.1 0.8 3.1 0.1 1.3 5.5 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.0 2.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 1.0 0.7 183.7 0.1 0.7 0.0 1.0 0.0 0.4 0.7 0.0 0.0 0.4 0.7 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.5 3.2 2.3 0.0 0.9 1.7 0.4 0.0 0.0 0.0 0.1 0.3 0.2 1.5 0.6 0.0 0.0 0.0 0.7 1.6 0.0 0.0 1.6 0.0 0.2 44.6 0.0 5.7 0.0 0.0 0.0 0.7 0.0 0.0 10.1 0.0 243.8 2.6 7.0 0.0 0.0 0.5 0.0 14.7 2.7 0.1 0.0 3.7 1.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 21.4 0.0 0.1 0.1 0.5 0.1 1.5 0.0 0.0 0.0 0.5 0.0 0.1 0.1 2.7 0.3 0.6 0.0 4.2 0.2 CCL3 "G0S19-1, LD78ALPHA, MIP-1-alpha, SCYA3" ENSG00000277632 "C-C motif chemokine ligand 3" P10147 17 36088256-36090169 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 76.7;lung: 35.8;lymphoid tissue: 49.4" "Cell type enhanced" "Detected in many" "dendritic cells: 441.4;Hofbauer cells: 2084.4;Kupffer cells: 723.2;Langerhans cells: 710.0;Macrophages: 1534.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "gdT-cell: 23.6" "Group enriched" "Detected in many" 4 "B-cells: 10.4;granulocytes: 10.8;T-cells: 23.6" "Cell line enhanced" "Detected in some" "Karpas-707: 443.8;U-266/70: 602.5;U-266/84: 2043.3" "Secreted to blood" NA NA 138000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 16: U-266 - Nucleosome" "Cluster 4: Macrophages - Innate immune response" "unprognostic (2.41e-1)" "unprognostic (1.87e-1)" "unprognostic (1.45e-1)" "unprognostic (7.44e-3)" "unprognostic (1.44e-1)" "unprognostic (1.66e-1)" "unprognostic (3.54e-1)" "unprognostic (8.90e-2)" "unprognostic (7.92e-3)" "unprognostic (2.00e-1)" "unprognostic (7.20e-2)" "unprognostic (2.05e-1)" "unprognostic (8.92e-3)" "unprognostic (1.08e-1)" "unprognostic (9.29e-2)" "unprognostic (1.55e-2)" "unprognostic (1.23e-2)" 17.6 16.0 0.0 8.1 0.7 76.7 5.6 0.0 1.4 1.5 0.0 2.5 0.0 1.1 0.0 0.5 2.9 10.3 3.7 0.0 0.0 4.6 12.9 35.8 1.8 0.7 0.0 1.2 1.3 0.0 1.7 2.4 0.0 2.2 0.0 0.0 5.6 0.0 0.8 0.8 3.1 0.0 0.0 49.4 3.0 0.7 0.5 0.0 2.0 0.0 0.0 3.0 1.4 1.4 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 443.8 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 55.6 0.0 0.0 1.3 602.5 2043.3 0.0 0.0 0.0 0.0 0.0 2.1 10.8 23.6 1.3 0.0 5.1 0.0 6.1 0.4 10.4 0.1 6.8 10.5 3.5 1.3 0.0 0.0 11.6 0.0 0.7 0.0 1.4 0.0 0.0 0.7 0.0 0.0 0.0 0.5 1.4 33.0 0.0 28.6 0.0 45.3 27.9 2.0 0.2 1.2 1.8 23.1 50.0 2.2 4.3 4.4 0.0 0.0 19.0 441.4 0.7 0.0 0.6 1.5 1.6 2.5 115.9 0.0 61.9 0.0 0.2 22.6 14.5 2.0 2.8 23.5 0.1 27.1 9.1 2084.4 0.0 0.0 0.5 0.0 723.2 710.0 1.9 1.8 1534.2 94.3 2.8 23.5 2.1 106.1 0.0 0.0 0.4 0.0 0.0 344.8 1.2 0.0 0.9 2.2 3.7 6.6 2.3 9.2 0.5 0.6 0.6 28.8 54.3 248.0 0.1 0.2 1.3 CCN2 "CTGF, IGFBP8" ENSG00000118523 "Cellular communication network factor 2" P29279 6 131948176-131951372 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cell adhesion, DNA synthesis" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 101.2;Cardiomyocytes: 38.7;Extravillous trophoblasts: 47.1;Fibroblasts: 261.8;Smooth muscle cells: 104.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "naive B-cell: 8.1" "Lineage enriched" "Detected in single" 81 "B-cells: 8.1" "Cell line enhanced" "Detected in many" "EFO-21: 1605.0;HUVEC TERT2: 1377.0;TIME: 2874.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005123, HPA031074, HPA031075" Approved Approved "Golgi apparatus,Vesicles" "Secreted in other tissues" No No 1010000 5900000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "CAB005123: AB_638805, HPA031074: AB_10599618, HPA031075: AB_10611248" "unprognostic (2.87e-1)" "unprognostic (1.43e-1)" "unprognostic (4.41e-2)" "unprognostic (5.68e-2)" "unprognostic (9.79e-2)" "unprognostic (1.82e-2)" "unprognostic (3.38e-1)" "unprognostic (4.96e-2)" "unprognostic (1.68e-1)" "unprognostic (3.89e-2)" "unprognostic (2.39e-1)" "unprognostic (2.06e-1)" "unprognostic (1.27e-3)" "prognostic unfavorable (5.04e-4)" "unprognostic (1.62e-1)" "unprognostic (1.77e-2)" "unprognostic (3.84e-3)" 265.9 107.5 18.9 168.0 18.8 2.0 206.4 16.3 34.0 531.0 31.5 148.8 43.7 418.5 34.4 271.9 243.8 441.4 371.8 25.8 14.2 235.7 82.9 226.3 73.6 18.8 32.1 77.0 194.0 43.0 44.8 198.2 20.2 364.6 136.1 2.4 138.2 154.3 51.8 155.1 151.2 576.3 14.2 569.1 182.6 24.7 20.8 49.5 464.7 61.9 14.9 324.0 102.5 18.2 4.6 7.5 126.8 3.7 279.9 158.5 1.8 373.1 178.2 226.8 119.4 0.2 12.2 0.6 1605.0 482.7 185.0 6.2 4.2 26.4 211.3 2.5 3.5 0.2 55.7 137.3 109.6 0.3 0.5 232.2 5.9 163.9 40.2 340.7 1377.0 0.0 0.4 0.3 650.8 2.5 0.5 1.2 61.8 41.3 21.7 32.6 6.0 0.7 81.9 0.4 0.5 0.8 38.3 62.2 18.3 308.5 6.1 3.1 2874.4 311.6 242.4 397.8 694.0 11.5 1.7 4.1 42.5 0.7 399.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 18.9 18.8 16.3 34.0 25.8 14.2 18.8 32.1 20.2 14.2 20.8 18.2 101.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.7 0.0 0.0 0.0 0.0 17.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 0.0 0.0 47.1 261.8 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 104.4 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 CCNB1IP1 "C14orf18, HEI10" ENSG00000100814 "Cyclin B1 interacting protein 1" Q9NPC3 14 20311368-20333312 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Meiosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 381.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "unprognostic (4.79e-2)" "unprognostic (1.35e-1)" "unprognostic (1.29e-1)" "unprognostic (9.37e-2)" "unprognostic (5.46e-3)" "unprognostic (2.79e-2)" "unprognostic (8.43e-2)" "unprognostic (5.88e-2)" "unprognostic (1.56e-1)" "unprognostic (1.88e-2)" "unprognostic (4.87e-2)" "unprognostic (4.77e-2)" "prognostic favorable (5.18e-6)" "unprognostic (2.12e-1)" "unprognostic (1.54e-2)" "unprognostic (4.43e-1)" "unprognostic (1.52e-1)" 31.3 20.0 31.7 10.6 32.8 35.5 58.1 31.8 44.3 52.6 38.4 35.3 21.3 43.0 48.4 27.3 53.2 20.8 74.7 31.1 35.3 66.4 74.9 36.9 25.3 34.7 32.7 99.4 45.3 51.3 22.2 31.3 34.9 38.1 30.1 21.2 29.6 24.4 52.2 35.5 24.7 29.9 32.7 20.4 31.0 23.3 31.8 32.0 57.4 63.4 30.7 40.0 41.7 34.4 30.8 24.7 137.5 133.3 68.9 94.1 110.3 37.0 73.6 55.5 72.8 83.2 33.4 106.2 23.9 27.1 55.6 53.8 96.6 69.9 74.3 30.9 82.0 63.1 22.6 79.7 201.7 117.5 56.6 128.8 114.6 39.6 381.3 67.3 42.6 125.7 77.7 82.1 37.0 48.9 68.5 79.3 83.2 66.5 46.6 82.9 67.9 45.5 58.7 44.6 109.0 113.6 25.5 58.5 170.7 75.8 18.7 84.5 18.4 31.6 40.1 38.4 48.8 38.3 51.0 72.6 10.6 97.3 37.1 6.3 4.2 0.1 8.2 1.4 10.9 11.6 9.0 10.3 17.7 9.8 9.2 13.0 0.6 6.0 1.6 18.2 13.3 3.8 31.7 32.8 31.8 44.3 31.1 35.3 34.7 32.7 34.9 32.7 31.8 34.4 22.2 28.9 27.2 16.3 35.5 58.1 74.0 45.5 113.3 4.2 57.0 71.9 30.9 58.6 21.0 23.9 20.9 41.2 27.7 15.1 103.7 31.8 64.2 13.0 37.6 24.9 41.3 34.7 22.2 38.2 70.6 34.5 23.0 20.2 34.9 76.7 20.0 35.3 17.8 1.7 28.5 40.1 28.5 23.3 26.5 92.8 51.6 22.4 51.6 7.5 17.8 46.9 30.9 15.1 19.7 29.3 18.8 44.0 17.4 63.5 21.0 86.5 5.2 17.6 46.0 36.6 31.6 101.0 77.5 67.0 40.1 34.1 28.7 61.1 44.3 51.3 CCNY "C10orf9, CBCP1, CFP1" ENSG00000108100 "Cyclin Y" Q8ND76 10 35247025-35572669 "Predicted intracellular proteins" "Cell cycle, Cell division, Wnt signaling pathway" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Late spermatids: 3651.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 26.4" "Group enriched" "Detected in all" 5 "dendritic cells: 7.8;granulocytes: 26.4;monocytes: 23.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036290 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA036290: AB_10600860" "unprognostic (1.25e-2)" "unprognostic (1.48e-1)" "unprognostic (4.30e-2)" "unprognostic (2.23e-3)" "unprognostic (1.30e-1)" "unprognostic (4.65e-1)" "prognostic unfavorable (6.75e-5)" "unprognostic (3.37e-2)" "unprognostic (6.15e-3)" "unprognostic (4.06e-2)" "unprognostic (2.94e-1)" "unprognostic (1.10e-1)" "unprognostic (2.74e-2)" "unprognostic (1.31e-1)" "unprognostic (3.77e-2)" "unprognostic (1.98e-1)" "unprognostic (1.80e-1)" 28.6 21.9 35.1 21.2 37.1 35.9 23.7 31.6 35.1 21.8 24.8 28.4 21.5 28.4 26.9 20.5 22.2 22.7 33.1 37.0 32.4 24.8 31.0 25.9 23.4 32.0 33.6 25.2 20.6 17.9 15.5 38.7 31.9 18.3 20.0 19.3 17.0 20.1 25.5 19.3 22.2 25.7 32.3 24.4 26.3 81.2 35.5 22.5 29.6 22.9 21.0 25.4 17.3 33.4 52.3 22.2 29.3 28.2 41.6 56.5 38.2 27.4 27.7 26.0 24.9 32.4 51.7 33.2 38.1 44.1 22.7 27.1 26.3 34.6 27.7 105.0 17.3 62.0 16.0 42.4 45.8 22.7 28.3 40.3 48.1 39.9 27.1 57.6 63.3 38.3 49.1 27.3 51.6 33.2 39.9 19.6 11.2 29.6 46.2 33.0 54.4 20.7 33.2 24.6 25.8 39.3 21.5 42.7 38.6 25.4 36.9 41.8 75.5 32.1 38.6 49.4 23.9 18.3 16.6 24.4 56.0 46.6 15.1 1.7 23.4 5.2 3.3 6.5 3.6 3.1 3.2 3.5 7.8 2.4 3.2 3.6 26.4 2.9 3.4 4.0 2.3 7.6 35.1 37.1 31.6 35.1 37.0 32.4 32.0 33.6 31.9 32.3 35.5 33.4 102.2 32.1 25.9 91.1 23.4 26.9 14.1 29.0 13.6 43.5 30.2 28.7 33.1 41.5 32.1 38.6 20.9 12.0 35.2 25.8 5.9 16.5 709.0 29.5 37.2 59.8 52.8 12.4 205.5 27.8 18.1 34.4 20.4 33.4 16.5 35.3 32.5 85.3 28.9 48.8 130.0 29.0 26.4 80.4 46.9 3651.5 41.3 56.6 16.0 192.0 89.3 62.4 24.7 167.9 445.2 27.9 19.2 38.7 11.7 27.7 31.5 23.1 28.5 39.6 6.6 56.0 26.5 33.8 40.2 17.1 29.5 9.4 26.2 43.2 28.6 20.9 CCPG1 "CPR8, KIAA1254" ENSG00000260916 "Cell cycle progression 1" Q9ULG6 15 55340032-55408510 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 279.2;neutrophil: 296.6" "Group enriched" "Detected in all" 7 "granulocytes: 296.6;monocytes: 84.2" "Cell line enhanced" "Detected in many" "HHSteC: 223.9;Karpas-707: 337.4;U-266/84: 259.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009432, HPA026861" Approved Approved "Endoplasmic reticulum,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "Endoplasmic reticulum" "HPA009432: AB_2668242, HPA026861: AB_1846192" "unprognostic (3.14e-2)" "unprognostic (2.94e-2)" "unprognostic (3.03e-1)" "unprognostic (2.51e-2)" "unprognostic (1.13e-1)" "unprognostic (1.28e-1)" "unprognostic (1.40e-2)" "unprognostic (8.34e-2)" "unprognostic (1.59e-1)" "unprognostic (1.94e-1)" "unprognostic (3.17e-2)" "unprognostic (2.61e-2)" "prognostic unfavorable (5.07e-4)" "prognostic unfavorable (5.02e-5)" "unprognostic (1.15e-1)" "unprognostic (1.71e-2)" "unprognostic (1.72e-2)" 38.9 37.8 24.0 23.7 27.7 63.8 34.1 23.1 28.4 61.1 36.8 33.3 24.3 26.7 36.1 20.1 22.0 53.8 56.2 24.7 26.9 51.5 66.9 39.3 22.2 18.4 17.3 22.9 84.8 73.3 32.3 27.4 17.7 41.0 33.2 48.2 77.1 42.3 53.0 13.5 25.6 33.5 17.2 28.7 47.5 29.6 27.3 12.2 84.4 35.3 24.2 29.9 9.7 22.9 13.9 47.7 10.9 24.4 173.6 59.3 15.5 30.0 56.4 17.2 26.1 14.4 23.5 20.8 99.5 97.5 33.6 18.7 9.5 25.1 14.4 55.5 14.2 28.1 58.4 12.8 223.9 39.6 84.2 49.5 59.8 35.6 34.4 143.3 65.2 0.8 47.7 337.4 55.1 17.9 0.2 19.3 6.5 54.4 11.8 6.2 17.4 84.8 36.1 10.1 14.0 21.5 35.3 19.5 151.4 35.0 31.0 85.1 65.7 50.8 11.1 38.9 20.4 65.2 259.6 13.0 95.6 77.2 41.0 220.8 59.4 279.2 26.8 50.7 22.5 18.1 16.6 20.7 27.6 13.4 13.9 20.0 296.6 25.7 84.2 4.7 23.0 32.9 24.0 27.7 23.1 28.4 24.7 26.9 18.4 17.3 17.7 17.2 27.3 22.9 92.3 115.4 118.1 0.0 44.6 15.4 30.3 99.2 13.6 68.7 40.2 40.1 14.4 50.1 136.5 88.3 93.8 29.3 42.9 43.7 5.9 60.9 136.2 49.6 41.0 60.1 16.7 25.2 0.0 145.3 23.2 78.6 33.1 62.3 39.1 30.0 76.1 96.1 51.0 85.8 0.0 28.8 114.0 55.9 25.2 216.1 56.5 71.7 48.0 0.0 89.8 72.6 38.1 0.0 0.0 67.6 45.1 116.6 180.8 42.6 29.5 36.7 123.8 128.0 52.6 80.2 48.1 43.3 41.1 11.8 16.6 24.6 41.8 70.0 16.2 21.8 CCR1 "CD191, CKR-1, CMKBR1, MIP1aR, SCYAR1" ENSG00000163823 "C-C motif chemokine receptor 1" P32246 3 46201711-46208313 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 42.5" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 81.2;Hofbauer cells: 117.4;Kupffer cells: 171.9;Macrophages: 74.2;monocytes: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Karpas-707: 330.3;RPMI-8226: 158.5;U-266/70: 57.7;U-266/84: 183.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.95e-1)" "unprognostic (2.17e-1)" "unprognostic (1.20e-1)" "unprognostic (2.16e-1)" "unprognostic (1.05e-1)" "unprognostic (6.66e-2)" "unprognostic (1.16e-1)" "unprognostic (8.82e-2)" "unprognostic (4.91e-3)" "unprognostic (2.20e-3)" "unprognostic (1.09e-1)" "unprognostic (9.60e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (1.08e-1)" "unprognostic (5.52e-3)" "unprognostic (1.47e-1)" "unprognostic (2.38e-1)" 21.0 4.7 2.1 42.5 2.3 24.8 4.0 2.4 3.1 2.5 2.6 5.6 7.3 2.5 1.6 3.4 2.8 11.7 2.4 1.9 2.6 4.9 17.2 18.7 10.9 5.2 3.2 2.1 3.1 1.9 0.9 26.4 4.5 1.6 7.3 0.3 2.1 2.6 1.3 0.6 6.6 15.5 4.7 30.8 4.9 1.7 4.9 5.7 1.0 3.3 10.2 16.7 0.7 7.4 0.3 0.0 0.0 0.0 0.0 3.3 0.2 0.0 0.2 0.0 0.3 0.7 1.5 0.1 0.4 0.0 3.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.5 6.1 0.1 0.0 0.2 0.1 0.0 0.0 0.2 0.0 330.3 0.0 0.2 0.2 13.0 0.0 0.0 0.0 0.1 0.0 158.5 0.0 5.6 0.0 0.0 0.0 0.4 1.3 0.9 0.2 35.5 0.0 0.8 0.0 0.0 0.2 57.7 183.7 0.1 29.1 26.5 0.4 82.5 125.1 25.8 10.5 76.2 50.1 2.9 0.1 8.5 53.9 0.2 0.1 1.4 113.4 84.5 51.3 18.9 0.1 50.6 2.1 2.3 2.4 3.1 1.9 2.6 5.2 3.2 4.5 4.7 4.9 7.4 0.3 3.2 3.0 0.0 2.0 0.9 0.0 0.0 0.6 0.0 0.1 0.5 0.6 0.0 1.3 0.0 0.0 1.3 15.9 0.0 1.9 0.0 0.4 0.1 0.6 1.6 0.0 1.7 0.0 0.0 81.2 2.4 0.0 0.0 3.8 0.0 1.4 1.2 117.4 0.0 0.0 0.0 0.0 171.9 23.5 0.1 0.0 74.2 5.4 9.4 51.5 0.2 7.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 3.2 1.5 0.2 0.0 0.4 0.5 0.0 0.2 0.2 1.7 2.9 6.0 0.0 0.0 0.0 CD109 "CPAMD7, DKFZp762L1111, FLJ38569" ENSG00000156535 "CD109 molecule" Q6YHK3 6 73695785-73828316 "CD markers, Plasma proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "parathyroid gland: 330.4" "Cell type enhanced" "Detected in many" "Adipocytes: 65.3;Basal respiratory cells: 62.8;Hofbauer cells: 45.0;Squamous epithelial cells: 51.4;Suprabasal keratinocytes: 43.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 206.4;BJ hTERT+: 126.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008992, HPA015723" Enhanced Supported "Plasma membrane,Cytosol" NA NA 180000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA008992: , HPA015723: AB_2732415" "unprognostic (2.28e-1)" "unprognostic (1.03e-1)" "unprognostic (7.76e-2)" "unprognostic (1.52e-2)" "unprognostic (9.17e-3)" "unprognostic (1.36e-1)" "unprognostic (1.03e-3)" "unprognostic (1.23e-3)" "unprognostic (7.49e-2)" "unprognostic (2.47e-1)" "unprognostic (1.15e-3)" "unprognostic (8.81e-2)" "prognostic unfavorable (2.65e-4)" "prognostic unfavorable (7.96e-5)" "unprognostic (9.50e-2)" "unprognostic (2.02e-1)" "prognostic unfavorable (4.68e-4)" 8.6 1.1 2.3 2.4 2.5 2.8 5.5 2.1 2.1 9.9 0.7 6.9 1.3 12.5 5.6 10.2 3.2 4.1 5.8 2.0 4.0 7.0 1.1 6.6 1.0 3.2 3.6 0.7 0.5 330.4 0.4 6.5 3.5 3.6 2.9 0.2 3.4 2.5 1.2 18.9 2.2 12.6 3.7 2.1 1.1 1.8 2.5 3.1 1.3 3.3 2.2 4.5 7.4 3.1 35.6 29.4 1.5 0.1 48.2 206.4 0.0 30.5 126.0 9.0 18.4 0.1 20.2 0.0 19.7 63.5 19.5 96.5 3.5 60.9 12.1 8.5 5.5 11.5 21.0 5.8 10.1 0.0 0.3 60.7 52.4 18.6 68.7 34.2 71.6 3.9 0.0 0.2 45.0 0.8 0.8 0.0 2.4 0.3 18.9 2.6 8.4 40.6 4.8 3.6 0.0 0.1 68.6 0.7 30.8 1.3 0.8 5.8 68.7 96.8 10.1 17.2 28.5 0.7 17.9 0.1 40.3 0.1 89.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 2.3 2.5 2.1 2.1 2.0 4.0 3.2 3.6 3.5 3.7 2.5 3.1 65.3 3.2 1.7 39.8 1.1 41.4 8.4 62.8 35.9 0.3 2.2 2.2 13.0 0.0 16.3 0.0 0.0 0.4 1.2 0.1 1.9 0.1 23.4 10.8 10.5 38.0 0.0 7.6 4.0 0.0 0.5 25.0 0.5 15.0 2.5 0.0 21.0 0.6 45.0 0.0 3.3 0.1 4.1 2.7 28.5 21.0 0.6 13.5 23.2 19.7 3.3 0.0 0.0 1.5 1.0 0.4 0.0 0.0 1.7 10.8 0.0 23.5 16.0 0.2 0.0 7.4 13.2 1.0 3.5 51.4 43.8 1.4 4.6 1.4 0.2 7.2 CD14 ENSG00000170458 "CD14 molecule" P08571 5 140631728-140633701 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 403.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 2809.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3697.0" "Group enriched" "Detected in all" 5 "granulocytes: 942.3;monocytes: 3697.0" "Cell line enhanced" "Detected in many" "A549: 10.1;CACO-2: 17.0;SiHa: 21.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001887, HPA002127, CAB033631, CAB072865, CAB072866" Enhanced Approved Vesicles "Secreted to blood" NA NA 2750000000 10000000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" Vesicles "CAB033631: AB_781932, CAB072865: AB_2665714, CAB072866: AB_2665715, HPA001887: AB_1078442, HPA002127: AB_1078440" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (3.42e-3)" "unprognostic (3.89e-2)" "unprognostic (3.29e-2)" "unprognostic (1.54e-1)" "unprognostic (4.71e-3)" "unprognostic (4.88e-2)" "unprognostic (2.16e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.80e-5)" "unprognostic (1.20e-2)" "unprognostic (6.87e-3)" "unprognostic (8.12e-2)" "unprognostic (6.92e-2)" 134.5 151.3 15.9 236.1 16.0 68.8 50.5 14.7 33.1 27.9 26.8 55.9 31.4 23.5 21.0 23.9 40.5 79.8 35.6 14.5 23.2 41.6 403.4 91.6 107.9 33.6 26.4 21.4 27.0 16.7 35.5 183.0 29.6 18.3 47.6 4.0 121.8 30.4 10.6 13.5 38.0 111.7 25.4 87.6 33.9 26.6 30.3 20.9 23.0 17.5 23.0 102.5 12.6 42.1 0.1 10.1 0.1 0.8 1.3 0.3 0.5 0.9 4.7 1.9 2.1 17.0 3.1 0.4 1.0 5.9 1.4 4.9 0.0 2.6 0.5 0.1 1.4 0.3 1.1 2.0 5.1 1.1 0.3 4.8 0.3 0.3 1.5 0.4 0.0 0.3 0.3 0.3 1.7 0.3 0.1 1.2 0.4 0.3 0.3 0.4 0.6 1.8 0.2 0.1 3.6 1.3 21.1 0.5 0.5 0.2 0.3 2.1 0.6 0.4 0.4 1.9 2.1 0.8 1.6 0.8 0.4 0.5 0.1 13.5 3697.0 21.7 6.8 677.3 8.7 12.1 3.7 3.9 440.4 1.9 5.2 3.6 942.3 3.8 95.1 25.2 3.7 3034.0 15.9 16.0 14.7 33.1 14.5 23.2 33.6 26.4 29.6 25.4 30.3 42.1 17.9 9.6 27.6 0.7 9.0 5.1 3.4 5.2 6.2 7.2 164.9 23.4 2.6 22.8 18.3 1.8 0.0 18.1 5.3 77.2 1.9 5.1 2.3 0.6 1.7 46.5 7.2 29.5 0.7 1.8 16.3 19.7 1.1 1.0 8.8 0.6 340.2 348.0 2809.2 33.7 0.9 5.9 4.1 668.4 75.9 6.1 5.0 652.8 8.8 23.4 285.3 30.0 11.3 0.5 0.4 1.8 35.3 5.3 1.8 1.7 5.0 7.0 9.8 5.1 32.9 25.8 9.7 1.5 2.0 4.4 4.3 46.1 5.5 2.1 7.4 4.9 CD160 "BY55, NK1, NK28" ENSG00000117281 "CD160 molecule" O95971 1 145719471-145739288 "CD markers, Predicted secreted proteins" "Adaptive immunity, Angiogenesis, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 13.5" "Cell type enriched" "Detected in some" 6 "NK-cells: 410.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 6 "gdT-cell: 107.6;MAIT T-cell: 44.5;memory CD8 T-cell: 72.9;naive CD8 T-cell: 82.8;NK-cell: 85.9" "Group enriched" "Detected in all" 8 "NK-cells: 85.9;T-cells: 107.6" "Cell line enhanced" "Detected in some" "HeLa: 2.2" "Not detected" "Not detected" "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (6.54e-4)" "unprognostic (1.06e-1)" "unprognostic (4.25e-2)" "unprognostic (6.91e-2)" "unprognostic (3.33e-1)" "unprognostic (3.40e-2)" "unprognostic (1.35e-1)" "unprognostic (8.25e-3)" "unprognostic (5.76e-2)" "unprognostic (2.68e-1)" "unprognostic (2.24e-2)" "unprognostic (7.49e-3)" "unprognostic (3.48e-5)" "unprognostic (4.05e-2)" "unprognostic (2.03e-1)" "unprognostic (2.89e-2)" "unprognostic (2.92e-4)" 0.5 0.3 1.0 1.0 0.9 5.2 0.6 2.9 0.8 0.8 0.9 1.6 4.7 0.7 0.4 0.4 0.6 1.0 1.5 0.8 0.2 0.4 5.0 1.4 3.6 0.4 0.3 0.4 0.4 0.0 0.5 0.4 0.3 0.5 1.0 1.4 1.5 0.5 0.8 1.1 4.5 0.1 0.1 13.5 0.8 0.5 0.6 0.3 0.4 0.1 1.5 0.9 0.5 0.6 0.5 0.4 0.6 0.3 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.5 0.0 0.0 0.6 0.0 0.1 0.0 1.3 0.6 1.2 2.2 0.5 0.0 0.8 1.2 0.0 0.1 0.0 0.1 0.2 0.0 0.6 0.3 0.5 0.0 0.6 0.4 1.5 0.4 0.3 1.1 0.1 0.0 0.4 0.0 0.2 0.4 0.6 0.3 0.5 0.2 0.4 0.5 0.8 0.6 0.5 0.2 0.3 1.1 0.8 0.6 0.2 0.2 0.9 0.1 12.7 0.3 0.3 107.6 0.6 44.5 1.1 1.2 72.9 0.2 1.2 0.7 82.8 5.6 85.9 1.7 1.2 0.0 81.3 1.0 0.9 2.9 0.8 0.8 0.2 0.4 0.3 0.3 0.1 0.6 0.6 1.1 0.0 0.0 0.7 1.0 0.1 0.2 0.1 0.0 1.8 0.6 0.4 0.5 0.0 0.0 0.0 10.4 0.1 59.8 3.1 0.0 0.1 4.4 0.7 0.5 1.0 0.0 6.6 0.5 0.4 0.0 0.9 3.1 0.8 2.5 0.3 3.9 0.4 0.0 6.7 0.4 0.5 0.0 4.6 0.4 11.1 0.0 0.9 0.0 0.0 1.3 0.9 410.9 0.5 0.2 0.0 0.1 0.0 2.7 0.4 0.3 0.2 0.0 2.9 0.0 1.1 0.4 0.1 0.2 0.0 0.1 0.1 44.0 0.3 1.0 0.2 CD163 "M130, MM130, SCARI1" ENSG00000177575 "CD163 molecule" Q86VB7 12 7470811-7503893 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Acute phase, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 240.5" "Cell type enriched" "Detected in many" 4 "Kupffer cells: 1756.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 76.1;myeloid DC: 65.2" "Group enriched" "Detected in many" 40 "dendritic cells: 65.2;monocytes: 76.1" "Cell line enhanced" "Detected in some" "GAMG: 1.8;HSkMC: 1.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB002432, HPA046404, HPA051974" Enhanced Supported "Plasma membrane" "Secreted to blood" NA NA 903000000 1600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB002432: AB_563510, HPA046404: AB_2679655, HPA051974: AB_2681678" "unprognostic (1.13e-1)" "unprognostic (2.13e-1)" "unprognostic (5.02e-3)" "unprognostic (2.72e-1)" "unprognostic (6.17e-3)" "unprognostic (2.09e-1)" "unprognostic (1.02e-1)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.04e-1)" "unprognostic (6.50e-2)" "unprognostic (1.84e-2)" "unprognostic (8.77e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (1.20e-2)" 171.8 85.6 6.1 152.5 7.0 17.6 50.8 5.2 18.4 25.6 21.5 48.7 12.4 27.3 3.6 16.4 68.1 43.5 52.7 4.9 7.9 27.3 89.7 131.7 54.4 15.8 10.9 23.1 21.4 8.8 11.4 109.4 18.0 15.5 21.6 4.3 25.9 7.2 11.4 15.3 52.9 130.4 7.2 240.5 35.6 9.7 55.9 18.7 17.2 17.6 7.2 68.5 16.3 10.3 0.0 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 1.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 76.1 0.5 0.1 6.4 0.0 0.0 0.0 0.1 65.2 0.0 0.0 0.0 1.7 0.0 0.0 1.0 0.1 20.1 6.1 7.0 5.2 18.4 4.9 7.9 15.8 10.9 18.0 7.2 55.9 10.3 2.7 3.2 8.3 0.0 3.8 1.5 0.2 0.0 0.0 0.1 0.1 0.3 4.6 7.2 5.0 0.0 2.1 1.5 0.5 0.0 0.0 0.0 4.3 0.0 0.1 13.9 0.0 3.6 0.4 0.0 1.9 3.0 0.5 0.0 5.1 0.1 17.9 13.9 269.9 0.0 0.5 0.0 0.0 1756.1 30.9 6.4 5.0 387.9 0.0 2.8 41.1 0.9 1.0 0.0 0.0 0.0 0.0 1.2 1.0 0.1 0.0 0.2 1.6 0.2 118.3 1.7 4.0 3.9 2.6 0.5 1.0 3.0 1.3 0.0 0.0 0.1 CD180 "LY64, Ly78, RP105" ENSG00000134061 "CD180 molecule" Q99467 5 67179613-67196799 "CD markers, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.3" "Cell type enhanced" "Detected in some" "B-cells: 53.6;Hofbauer cells: 78.6;Kupffer cells: 23.5;Macrophages: 17.5;monocytes: 13.8;Plasma cells: 39.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 77.0;naive B-cell: 78.9" "Group enriched" "Detected in many" 25 "B-cells: 78.9;dendritic cells: 23.5;monocytes: 34.5" "Group enriched" "Detected in some" 10 "Daudi: 45.2;Karpas-707: 41.1;U-266/70: 33.1;U-266/84: 49.0;U-698: 12.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003740 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Mitotic spindle" Yes NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Nucleoplasm, Nucleoli, Mitotic spindle" "HPA003740: AB_1078450" "unprognostic (9.33e-2)" "unprognostic (4.58e-2)" "unprognostic (2.81e-3)" "unprognostic (5.85e-3)" "unprognostic (2.25e-2)" "unprognostic (4.04e-3)" "unprognostic (1.09e-1)" "unprognostic (4.95e-2)" "unprognostic (5.83e-2)" "unprognostic (3.71e-1)" "unprognostic (2.16e-1)" "unprognostic (1.46e-1)" "unprognostic (2.09e-1)" "unprognostic (1.16e-1)" "unprognostic (3.70e-2)" "unprognostic (1.21e-1)" "unprognostic (2.18e-2)" 1.6 0.7 0.7 9.7 0.7 2.4 6.7 0.6 1.2 0.5 0.4 2.1 2.0 0.5 0.2 0.4 0.4 1.6 0.4 0.8 0.7 0.3 2.5 1.6 23.2 1.5 1.5 0.2 0.3 0.2 0.1 3.2 2.0 0.5 2.7 0.3 1.1 0.4 0.1 0.2 3.9 1.8 1.0 12.9 2.2 0.4 1.8 2.5 0.3 0.2 23.3 3.0 0.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.2 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 41.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.1 0.6 0.2 33.1 49.0 12.3 0.0 2.7 0.0 0.3 11.8 0.9 0.0 20.4 0.0 77.0 0.1 0.1 22.1 78.9 0.0 0.0 0.9 1.8 34.5 23.5 0.1 8.5 0.7 0.7 0.6 1.2 0.8 0.7 1.5 1.5 2.0 1.0 1.8 2.1 0.1 0.0 0.5 0.3 53.6 0.4 0.1 0.0 0.0 0.1 1.8 1.1 0.7 1.5 0.0 0.0 0.0 0.4 4.0 0.0 0.0 0.0 2.2 0.1 0.0 0.6 0.0 1.7 0.0 0.2 0.3 0.4 0.0 0.1 2.5 0.0 0.0 0.3 78.6 0.0 0.0 0.0 0.0 23.5 8.0 1.0 0.0 17.5 0.0 1.9 13.8 0.1 0.0 0.0 0.0 0.3 0.0 0.0 39.6 0.0 0.0 0.1 0.7 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.7 2.2 0.0 0.1 0.1 CD19 ENSG00000177455 "CD19 molecule" P15391 16 28931965-28939342 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "intestine: 33.0;lymphoid tissue: 75.3" "Cell type enhanced" "Detected in some" "B-cells: 135.3;Early spermatids: 38.2;Plasma cells: 30.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 80 "memory B-cell: 138.2;naive B-cell: 172.1" "Lineage enriched" "Detected in many" 89 "B-cells: 172.1" "Cell line enhanced" "Detected in some" "Daudi: 143.3;REH: 77.1;U-698: 33.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB016110 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "CAB016110: AB_626952" "unprognostic (3.27e-3)" "unprognostic (1.19e-3)" "unprognostic (6.63e-2)" "unprognostic (1.09e-2)" "unprognostic (8.68e-3)" "unprognostic (3.11e-5)" "unprognostic (2.61e-1)" "unprognostic (6.96e-3)" "unprognostic (1.29e-2)" "unprognostic (4.29e-3)" "unprognostic (1.12e-1)" "unprognostic (1.30e-1)" "unprognostic (5.41e-6)" "unprognostic (2.06e-1)" "unprognostic (1.83e-1)" "unprognostic (1.36e-1)" "unprognostic (2.07e-1)" 0.6 0.1 0.0 28.5 0.1 6.2 0.1 0.9 0.4 0.1 0.0 2.0 0.9 0.2 0.1 0.9 0.2 0.9 0.1 0.0 0.0 0.7 0.3 0.5 72.1 0.2 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.5 1.6 0.1 1.2 0.1 0.0 0.0 33.0 0.2 0.0 72.7 3.9 3.8 0.2 5.7 1.2 0.0 75.3 2.8 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 143.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 77.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 33.0 0.0 0.1 0.0 1.9 0.2 0.2 0.0 0.3 0.0 138.2 0.1 0.0 0.3 172.1 0.4 0.1 1.3 0.3 0.4 0.2 0.0 7.2 0.0 0.1 0.9 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.3 0.2 0.0 0.6 0.0 135.3 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 1.5 0.2 0.0 0.0 38.2 1.5 0.0 1.0 0.0 0.8 0.0 0.0 0.8 0.8 0.5 0.1 0.0 0.4 1.4 0.3 1.7 0.0 0.0 0.1 0.0 0.8 0.6 7.9 0.3 1.1 3.6 0.0 0.2 0.5 0.0 0.0 0.0 0.1 0.1 0.7 30.5 0.2 0.3 0.1 0.5 0.1 0.0 0.1 0.1 7.4 4.2 0.0 0.0 0.7 2.4 0.6 0.5 0.1 CD1C CD1 ENSG00000158481 "CD1c molecule" P29017 1 158289923-158294774 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "lymphoid tissue: 130.4" "Cell type enriched" "Detected in some" 6 "Langerhans cells: 551.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "memory B-cell: 84.1;myeloid DC: 324.9" "Group enriched" "Detected in many" 8 "B-cells: 84.1;dendritic cells: 324.9" "Group enriched" "Detected in some" 10 "JURKAT: 14.8;MOLT-4: 49.4" HPA068359 Approved "Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA 200000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus, Vesicles" "Endoplasmic reticulum" "HPA068359: " "unprognostic (2.55e-3)" "prognostic favorable (1.79e-5)" "unprognostic (1.75e-5)" "unprognostic (3.09e-5)" "unprognostic (3.12e-2)" "unprognostic (8.13e-3)" "unprognostic (2.01e-1)" "unprognostic (3.80e-3)" "unprognostic (7.11e-3)" "unprognostic (1.87e-1)" "unprognostic (7.41e-2)" "unprognostic (1.93e-1)" "unprognostic (1.04e-1)" "unprognostic (1.46e-1)" "unprognostic (1.67e-1)" "unprognostic (8.05e-2)" "unprognostic (1.99e-1)" 2.7 0.8 0.0 17.3 0.0 1.1 5.0 0.0 0.2 2.3 0.0 3.4 2.0 2.4 0.6 4.5 1.8 7.7 2.0 0.0 0.0 1.2 4.1 6.5 26.2 0.0 0.0 0.9 0.7 0.6 0.2 0.1 0.0 1.8 9.4 0.0 2.8 1.3 1.0 12.2 12.0 3.1 0.0 23.0 3.7 0.9 0.0 130.4 0.7 1.1 38.2 4.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 49.4 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.9 0.0 0.6 26.8 0.1 0.1 24.7 0.3 84.1 0.1 0.0 324.9 49.1 0.2 0.0 1.1 4.1 3.7 1.5 0.5 15.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 5.2 0.0 26.6 13.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 4.1 0.0 0.1 1.5 0.0 0.8 0.0 0.0 0.1 1.4 0.0 0.0 3.8 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 7.1 551.4 4.5 0.0 91.2 19.6 0.0 11.8 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 1.5 0.0 0.0 0.2 0.4 0.1 0.3 0.0 7.4 0.0 1.9 0.0 0.0 0.0 CD209 "CDSIGN, CLEC4L, DC-SIGN, DC-SIGN1" ENSG00000090659 "CD209 molecule" Q9NNX6 19 7739993-7747564 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Endocytosis, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 34.2;placenta: 22.8" "Group enriched" "Detected in some" 4 "Kupffer cells: 15.6;Langerhans cells: 14.7;Macrophages: 12.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "classical monocyte: 1.4;intermediate monocyte: 1.4;myeloid DC: 1.2" "Group enriched" "Detected in many" 4 "dendritic cells: 1.2;monocytes: 1.4" "Cell line enriched" "Detected in single" 14 "THP-1: 3.3" "CAB032436, CAB033831" Supported "Intracellular and membrane" NA NA 3100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB032436: AB_639039, CAB033831: AB_1121347" "unprognostic (2.76e-1)" "unprognostic (1.15e-2)" "unprognostic (5.36e-3)" "unprognostic (1.25e-1)" "unprognostic (4.43e-2)" "unprognostic (1.40e-1)" "unprognostic (5.45e-2)" "unprognostic (3.83e-2)" "unprognostic (2.10e-2)" "unprognostic (1.24e-1)" "unprognostic (9.65e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.15e-5)" "unprognostic (1.70e-1)" "unprognostic (5.51e-2)" "unprognostic (6.17e-2)" "unprognostic (1.09e-1)" 34.2 3.9 0.3 8.6 0.6 0.4 4.4 1.3 3.0 4.0 5.7 10.5 14.3 1.4 1.0 4.8 2.5 8.6 4.5 0.3 0.7 2.1 3.3 4.9 18.1 1.0 0.6 1.0 1.0 0.8 0.7 22.8 0.8 0.8 13.9 0.1 2.1 1.9 0.9 1.4 19.3 10.6 0.9 2.4 4.1 2.1 0.6 5.4 1.4 1.5 2.3 20.2 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.0 1.4 0.0 0.1 0.0 0.0 1.2 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.4 0.3 0.6 1.3 3.0 0.3 0.7 1.0 0.6 0.8 0.9 0.6 0.8 0.3 0.0 0.0 0.0 0.4 0.5 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 1.3 0.0 0.0 0.1 3.5 0.0 0.0 0.0 0.0 15.6 14.7 0.3 0.0 12.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.1 0.9 0.1 0.1 0.0 0.0 0.1 CD300A "CMRF-35-H9, CMRF35H, IGSF12, IRC1, IRC2, Irp60" ENSG00000167851 "CD300a molecule" Q9UGN4 17 74466399-74484794 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 95.2" "Cell type enhanced" "Detected in some" "dendritic cells: 103.5;granulocytes: 59.5;Hofbauer cells: 114.0;Kupffer cells: 97.6;Macrophages: 90.9;NK-cells: 225.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "HMC-1: 104.4;NB-4: 45.9;RPMI-8226: 88.7" "HPA010971, HPA011645" Approved Approved "Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Vesicles, Cytosol" "HPA010971: , HPA011645: AB_1846988" "unprognostic (1.99e-1)" "unprognostic (4.60e-2)" "unprognostic (3.88e-2)" "unprognostic (3.30e-2)" "unprognostic (2.73e-1)" "unprognostic (2.01e-1)" "unprognostic (1.04e-2)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "unprognostic (1.17e-2)" "unprognostic (7.87e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (5.97e-2)" "unprognostic (5.45e-3)" "unprognostic (1.36e-1)" "unprognostic (5.72e-2)" 10.6 7.5 6.7 31.1 7.1 24.4 4.6 7.1 31.1 2.8 7.5 9.2 11.3 3.5 1.8 3.5 3.1 14.2 4.7 6.9 7.8 3.5 14.6 18.1 27.0 11.4 8.6 1.5 3.2 1.4 3.6 13.9 13.2 4.0 8.6 1.0 4.0 2.5 1.6 4.5 13.5 11.7 9.2 95.2 4.9 1.2 12.1 14.1 2.3 2.7 11.7 9.5 2.6 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 5.5 104.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 1.5 45.9 0.0 0.0 0.0 0.2 0.0 88.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 17.1 0.0 845.6 170.3 481.9 226.4 374.2 48.3 18.9 45.5 67.5 159.2 6.4 16.7 52.5 560.5 456.5 387.6 149.7 3.1 197.0 6.7 7.1 7.1 31.1 6.9 7.8 11.4 8.6 13.2 9.2 12.1 12.5 1.0 0.0 7.4 0.3 7.8 0.9 0.1 0.2 0.0 0.0 0.6 1.8 0.6 1.5 0.7 0.0 0.0 0.7 103.5 0.1 0.0 0.1 0.0 0.6 0.2 2.5 0.0 5.7 0.1 0.0 1.2 0.8 0.5 0.7 59.5 0.0 2.2 1.3 114.0 0.0 0.3 0.2 0.0 97.6 24.0 0.4 0.0 90.9 3.6 5.6 36.6 0.0 225.6 1.0 0.0 0.0 0.1 0.0 14.5 0.1 0.0 0.4 0.6 0.1 6.6 0.6 0.5 0.0 0.4 0.2 0.6 1.5 33.2 0.0 0.2 0.2 CD33 "FLJ00391, p67, SIGLEC-3, SIGLEC3" ENSG00000105383 "CD33 molecule" P20138 19 51225064-51243860 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.4;lymphoid tissue: 23.9" "Group enriched" "Detected in some" 6 "granulocytes: 76.0;Hofbauer cells: 78.8;Kupffer cells: 131.2;Langerhans cells: 41.4;Macrophages: 53.5;monocytes: 65.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 166.5;intermediate monocyte: 122.0;myeloid DC: 213.5;non-classical monocyte: 57.8" "Group enriched" "Detected in many" 9 "dendritic cells: 213.5;monocytes: 166.5" "Cell line enhanced" "Detected in some" "HEL: 86.1;HL-60: 115.6;HMC-1: 82.4;NB-4: 55.2;RPMI-8226: 62.5;THP-1: 67.0;U-937: 84.1" "CAB011442, HPA035832, HPA064807, CAB079996" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 3400000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Plasma membrane" "CAB011442: , CAB079996: , HPA035832: AB_2674808, HPA064807: AB_2685356" "unprognostic (1.18e-2)" "unprognostic (1.45e-2)" "unprognostic (2.80e-2)" "unprognostic (7.14e-2)" "unprognostic (3.71e-1)" "unprognostic (9.43e-2)" "unprognostic (2.59e-1)" "unprognostic (5.90e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-1)" "unprognostic (2.53e-1)" "unprognostic (6.28e-2)" "unprognostic (6.88e-4)" "unprognostic (7.79e-2)" "unprognostic (3.35e-2)" "unprognostic (6.49e-2)" "unprognostic (1.67e-1)" 7.9 3.4 1.1 11.2 1.2 32.4 2.5 1.5 1.6 3.0 2.5 3.2 3.3 1.7 1.3 2.0 2.5 6.6 2.0 1.1 1.8 1.4 5.5 12.6 10.1 2.5 1.6 1.4 1.4 1.2 0.9 6.9 2.4 1.4 4.2 0.2 1.8 2.6 0.9 2.7 4.4 7.1 1.9 23.9 2.3 1.0 2.3 3.5 0.9 0.8 3.5 6.2 1.3 3.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.2 0.0 5.5 0.4 0.0 1.3 0.3 0.0 0.2 0.0 0.1 0.1 86.1 0.3 0.0 0.0 115.6 82.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 16.2 21.2 0.2 0.0 0.0 55.2 0.2 0.0 25.9 0.0 4.4 62.5 0.4 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 67.0 0.7 14.0 1.1 1.8 0.1 0.3 7.6 0.2 9.6 84.1 0.4 17.9 166.5 11.0 0.3 122.0 0.4 0.1 0.2 0.5 213.5 0.4 0.3 0.2 20.5 15.5 57.8 6.3 1.1 77.8 1.1 1.2 1.5 1.6 1.1 1.8 2.5 1.6 2.4 1.9 2.3 3.6 0.7 0.0 6.7 0.0 1.0 1.8 0.5 0.0 0.0 0.2 1.4 0.4 0.8 0.0 0.6 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.7 0.1 0.1 3.0 0.0 4.2 0.0 0.0 0.5 1.1 0.0 0.1 76.0 0.1 5.3 0.7 78.8 0.0 0.0 0.0 0.0 131.2 41.4 1.7 0.3 53.5 1.8 11.2 65.0 0.2 1.0 0.5 0.2 0.0 0.0 0.0 0.3 0.4 0.0 0.2 0.7 0.6 0.0 1.1 0.3 0.7 0.5 0.0 1.0 0.8 2.5 0.1 0.0 0.4 CD36 "FAT, GP3B, GP4, GPIV, SCARB3" ENSG00000135218 "CD36 molecule" P16671 7 80369575-80679277 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Transport" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1533.6" "Cell type enhanced" "Detected in many" "Adipocytes: 3219.2;Cardiomyocytes: 623.1;Hofbauer cells: 1369.8;Sertoli cells: 696.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 962.6;intermediate monocyte: 270.6;myeloid DC: 507.1" "Group enriched" "Detected in all" 46 "dendritic cells: 507.1;monocytes: 962.6" "Group enriched" "Detected in some" 4 "ASC diff: 322.6;HEL: 158.1" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "spinal cord: 16.9" "HPA002018, CAB025866, HPA071026" Enhanced Enhanced "Golgi apparatus" NA NA 5300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "CAB025866: , HPA002018: AB_1078464, HPA071026: AB_2732170" "unprognostic (7.16e-2)" "unprognostic (1.80e-2)" "unprognostic (1.06e-3)" "unprognostic (6.52e-2)" "unprognostic (2.05e-1)" "unprognostic (1.28e-1)" "unprognostic (2.63e-1)" "unprognostic (9.35e-2)" "unprognostic (2.64e-2)" "unprognostic (1.97e-1)" "unprognostic (1.23e-3)" "unprognostic (1.18e-1)" "unprognostic (1.84e-3)" "prognostic unfavorable (4.47e-4)" "unprognostic (7.05e-3)" "unprognostic (4.87e-2)" "unprognostic (2.73e-3)" 1533.6 24.6 3.4 51.7 2.5 148.2 540.4 1.6 2.0 11.6 2.7 40.5 113.6 8.7 38.2 19.6 40.5 84.0 540.9 2.6 6.9 7.0 80.8 131.2 18.8 22.0 21.2 4.0 31.2 25.0 2.0 413.3 15.7 5.0 40.9 0.3 31.9 8.6 248.5 28.6 119.7 39.4 14.0 309.9 31.2 7.7 24.0 22.1 69.1 381.6 7.2 22.2 13.4 3.9 0.0 0.0 1.0 0.2 322.6 3.3 0.7 0.9 10.7 0.1 0.1 0.0 0.0 0.1 0.6 1.4 0.3 0.1 4.3 0.5 0.1 0.6 0.4 158.1 0.5 25.7 0.2 0.1 0.1 31.0 12.6 0.1 0.2 7.7 0.9 0.0 5.8 0.0 1.8 0.2 0.1 1.0 0.0 0.0 0.0 0.2 0.0 0.5 0.5 0.1 0.9 1.3 0.8 0.6 0.3 2.7 11.1 19.3 0.4 0.5 0.5 0.6 0.3 0.2 0.8 0.4 0.1 54.3 41.8 12.3 962.6 3.7 1.9 270.6 2.1 3.6 0.6 0.6 507.1 0.5 0.8 0.4 15.8 5.9 72.0 128.3 1.5 692.4 3.4 2.5 1.6 2.0 2.6 6.9 22.0 21.2 15.7 14.0 24.0 3.9 3219.2 6.4 63.1 0.0 7.9 7.4 0.2 3.0 0.6 0.2 189.9 24.8 623.1 4.3 9.8 7.3 0.0 10.1 55.0 0.0 0.0 0.2 11.7 5.0 5.9 303.3 0.0 419.5 6.3 0.0 11.1 69.6 1.1 38.4 15.2 0.6 406.2 9.0 1369.8 0.0 2.2 0.6 8.2 153.7 67.3 3.9 0.6 159.6 16.0 17.8 255.2 0.0 7.2 0.5 1.3 0.1 0.0 0.0 4.2 0.8 9.9 0.4 1.2 0.3 696.8 33.1 452.1 4.6 0.7 0.8 4.7 18.3 5.9 1.9 0.2 0.3 CD40LG "CD154, CD40L, gp39, hCD40L, HIGM1, IMD3, TNFSF5, TRAP" ENSG00000102245 "CD40 ligand" P29965 X 136648158-136660390 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 15.5" "Cell type enriched" "Detected in some" 8 "T-cells: 76.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 26.3;MAIT T-cell: 64.1;memory CD4 T-cell: 80.5;naive CD4 T-cell: 76.1" "Lineage enriched" "Detected in many" 39 "T-cells: 80.5" "Cell line enriched" "Detected in some" 15 "MOLT-4: 23.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045827, HPA072480" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 776000 20000 "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus, Plasma membrane" "HPA045827: AB_10959606, HPA072480: " "unprognostic (1.94e-5)" "unprognostic (1.24e-2)" "unprognostic (3.26e-1)" "unprognostic (1.27e-3)" "unprognostic (4.71e-2)" "unprognostic (3.56e-5)" "unprognostic (3.66e-2)" "unprognostic (5.48e-3)" "unprognostic (2.77e-1)" "unprognostic (2.14e-4)" "unprognostic (1.87e-1)" "unprognostic (1.55e-1)" "unprognostic (6.70e-4)" "unprognostic (2.15e-1)" "unprognostic (5.19e-2)" "unprognostic (2.36e-3)" "unprognostic (2.92e-2)" 0.8 0.3 0.1 7.9 0.0 1.9 1.1 0.2 0.2 0.9 0.2 1.9 1.8 0.3 0.2 1.0 0.4 2.0 0.2 0.1 0.2 0.4 1.0 2.4 15.5 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.2 0.8 3.1 0.0 0.6 0.3 0.1 0.6 3.8 0.6 0.0 4.9 2.0 0.3 0.1 15.5 0.5 0.2 14.8 2.5 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.3 26.3 0.1 64.1 0.1 80.5 11.7 0.2 0.0 76.1 0.7 1.3 0.8 0.1 0.1 10.5 13.6 0.1 0.0 0.2 0.2 0.1 0.2 0.1 0.1 0.2 0.0 0.1 0.2 0.6 0.0 2.4 0.0 2.4 1.3 0.0 0.0 0.0 0.0 0.4 0.5 0.3 0.0 0.6 0.0 0.0 0.0 4.5 0.0 0.0 0.0 3.9 0.0 0.0 0.6 0.0 1.7 0.0 0.0 0.0 0.6 2.6 0.0 1.3 0.0 1.1 0.3 0.1 0.0 0.0 0.0 0.0 0.6 4.0 8.9 0.0 2.9 1.8 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.1 2.0 0.0 76.6 0.0 0.0 0.1 CD5 "LEU1, T1" ENSG00000110448 "CD5 molecule" P06127 11 61102489-61127852 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 46.5" "Cell type enhanced" "Detected in some" "dendritic cells: 7.5;Langerhans cells: 9.3;Muller glia cells: 16.0;T-cells: 57.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 138.2" "Lineage enriched" "Detected in many" 33 "T-cells: 138.2" "Group enriched" "Detected in some" 66 "JURKAT: 21.0;MOLT-4: 70.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB015392, CAB020308, HPA043416, HPA060839" Enhanced NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "CAB015392: AB_2075324, CAB020308: , HPA043416: AB_2678472, HPA060839: AB_2684376" "prognostic favorable (4.05e-4)" "prognostic favorable (9.16e-5)" "unprognostic (2.33e-1)" "prognostic favorable (9.00e-5)" "unprognostic (1.02e-2)" "prognostic favorable (7.41e-6)" "unprognostic (2.45e-3)" "unprognostic (1.37e-2)" "prognostic favorable (3.93e-4)" "unprognostic (1.25e-2)" "unprognostic (5.00e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (8.94e-5)" "unprognostic (4.78e-2)" "unprognostic (1.02e-2)" "unprognostic (2.38e-1)" "unprognostic (1.06e-1)" 1.4 0.9 0.4 22.6 0.4 12.2 1.0 0.1 0.5 0.9 0.0 2.8 3.1 0.7 0.4 2.3 0.8 4.9 0.9 0.6 0.4 0.8 1.5 5.7 38.0 0.2 0.0 0.8 0.4 0.2 0.4 0.3 0.5 1.0 2.7 1.8 6.4 0.3 0.6 1.4 7.1 1.2 0.0 14.1 7.9 0.8 0.3 46.5 1.0 0.3 22.2 6.2 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 21.0 0.0 0.0 0.0 0.1 70.5 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.4 0.6 45.9 0.4 32.8 1.5 108.7 72.5 3.7 3.4 88.4 69.8 1.8 0.4 3.4 4.1 138.2 61.5 0.4 0.4 0.1 0.5 0.6 0.4 0.2 0.0 0.5 0.0 0.3 0.0 0.4 0.0 1.7 0.0 4.1 0.9 0.0 0.0 0.0 0.2 0.4 0.5 0.3 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 2.7 0.0 0.1 0.2 0.0 1.3 0.3 0.0 0.0 0.9 2.6 0.1 1.3 0.0 1.1 0.0 0.1 0.0 0.2 0.1 0.0 0.0 9.3 0.9 0.0 1.8 3.6 0.0 2.1 16.0 1.0 0.0 0.1 0.1 0.3 0.0 6.3 0.0 0.0 0.1 0.0 1.3 0.0 0.1 0.6 0.4 0.7 0.2 0.3 0.0 57.0 0.0 0.2 0.2 CD53 "MOX44, TSPAN25" ENSG00000143119 "CD53 molecule" P19397 1 110871188-110899922 "CD markers, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 448.3" "Cell type enhanced" "Detected in many" "B-cells: 310.0;dendritic cells: 375.0;Hofbauer cells: 365.7;Kupffer cells: 324.3;Macrophages: 294.8;NK-cells: 383.1;T-cells: 297.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 473.5;HDLM-2: 214.8;HMC-1: 298.4;Karpas-707: 188.1;U-266/70: 251.2;U-698: 149.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047216 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "HPA047216: AB_2679986" "unprognostic (2.93e-2)" "unprognostic (1.25e-2)" "unprognostic (7.45e-3)" "unprognostic (1.02e-3)" "unprognostic (8.88e-2)" "unprognostic (3.78e-2)" "unprognostic (2.96e-1)" "unprognostic (6.07e-2)" "unprognostic (2.83e-2)" "unprognostic (2.03e-1)" "unprognostic (5.09e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.60e-4)" "unprognostic (9.58e-2)" "unprognostic (4.95e-2)" "unprognostic (1.33e-1)" "unprognostic (7.72e-2)" 63.4 30.8 10.1 284.4 11.1 126.6 27.0 12.6 16.3 20.8 12.3 41.5 37.9 17.3 10.5 20.0 22.8 58.5 12.2 9.7 13.4 15.1 46.8 114.9 397.9 18.9 16.0 9.2 11.9 6.6 6.2 58.5 18.9 12.8 54.8 2.0 19.3 12.8 4.5 6.7 103.4 55.8 18.3 269.4 44.3 5.7 17.5 144.9 11.3 10.6 448.3 85.1 9.0 31.9 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 473.5 0.2 0.0 0.2 0.5 0.0 0.0 0.0 214.8 0.0 26.4 0.1 0.0 0.0 60.4 298.4 0.0 0.0 0.0 0.0 0.0 0.0 139.2 11.2 188.1 0.0 0.0 103.1 71.1 0.4 0.0 0.0 98.0 0.7 104.2 0.0 0.0 0.0 0.1 0.0 0.2 0.2 1.5 0.0 88.4 17.2 0.2 0.4 0.1 0.5 251.2 123.2 149.2 1.5 68.7 3.4 1483.0 779.5 479.0 732.4 808.6 658.1 794.0 527.8 649.2 631.9 745.1 377.9 552.5 1144.2 526.6 882.9 517.5 740.3 1621.0 10.1 11.1 12.6 16.3 9.7 13.4 18.9 16.0 18.9 18.3 17.5 31.9 4.2 16.0 24.4 0.7 310.0 7.0 0.6 0.0 0.6 0.0 2.3 5.1 1.0 5.7 8.6 1.8 0.0 2.1 375.0 0.2 0.0 0.5 0.4 0.4 0.5 13.0 0.0 42.9 5.8 0.2 5.4 6.7 7.1 0.6 162.2 0.0 16.4 6.7 365.7 0.0 1.4 0.3 0.0 324.3 161.5 1.9 2.1 294.8 39.2 69.3 156.3 0.1 383.1 1.0 0.6 0.3 0.1 0.4 134.0 0.3 0.0 1.6 4.4 0.6 6.6 1.9 1.8 0.1 0.6 1.1 5.5 4.1 297.0 0.0 0.2 0.3 CD5L "API6, Spalpha" ENSG00000073754 "CD5 molecule like" O43866 1 157830911-157898256 "Plasma proteins, Predicted secreted proteins" "Apoptosis, Immunity, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 572.9" "Group enriched" "Detected in some" 36 "Hofbauer cells: 279.0;Kupffer cells: 567.0" "Cancer enriched" "Detected in some" 5 "liver cancer: 4.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA065686, HPA068384" Enhanced "Secreted to blood" NA NA 4030000000 4300000000 "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA065686: AB_2685532, HPA068384: AB_2685979" "unprognostic (2.96e-1)" "unprognostic (2.90e-1)" "unprognostic (1.08e-1)" "unprognostic (1.94e-1)" "prognostic favorable (8.88e-5)" "unprognostic (1.73e-2)" "unprognostic (4.51e-2)" "unprognostic (1.89e-1)" "unprognostic (1.56e-1)" "unprognostic (5.95e-3)" "unprognostic (2.26e-1)" "unprognostic (1.06e-1)" "unprognostic (3.63e-1)" 1.4 0.0 0.0 1.5 0.0 17.3 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 104.7 1.6 9.2 0.2 0.1 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 572.9 0.5 0.1 0.1 6.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 6.1 6.1 279.0 0.0 0.0 0.0 0.0 567.0 0.0 1.3 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.3 0.3 0.0 0.0 0.0 CD7 "GP40, LEU-9, Tp40, TP41" ENSG00000173762 "CD7 molecule" P09564 17 82314868-82317608 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.6;lymphoid tissue: 53.7" "Group enriched" "Detected in many" 9 "dendritic cells: 625.0;NK-cells: 1299.7;T-cells: 527.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 231.5" "Group enriched" "Detected in many" 22 "NK-cells: 231.5;T-cells: 71.5" "Cell line enhanced" "Detected in some" "Hep G2: 52.0;JURKAT: 26.7;MOLT-4: 119.2" "Region enhanced" "Detected in some" "cerebral cortex: 3.2" "Not detected" "Not detected" "CAB002594, HPA039079" Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB002594: , HPA039079: AB_2676337" "unprognostic (3.14e-3)" "prognostic favorable (5.51e-4)" "unprognostic (1.89e-2)" "prognostic favorable (2.03e-5)" "unprognostic (7.69e-3)" "unprognostic (1.09e-3)" "unprognostic (3.28e-2)" "unprognostic (1.34e-1)" "prognostic favorable (2.69e-4)" "unprognostic (3.16e-2)" "unprognostic (1.03e-1)" "unprognostic (2.24e-1)" "prognostic unfavorable (7.75e-11)" "unprognostic (4.69e-2)" "unprognostic (1.55e-1)" "unprognostic (1.97e-1)" "unprognostic (1.55e-3)" 8.2 1.3 0.7 32.9 0.8 28.6 2.6 0.8 1.3 2.5 0.9 7.3 12.4 3.0 0.4 3.9 3.9 3.2 1.8 0.6 1.1 7.1 7.7 17.1 36.8 1.4 0.8 0.8 1.2 0.1 1.4 3.3 1.0 4.4 1.9 0.0 3.1 1.0 0.8 1.7 21.1 1.1 1.2 53.7 8.1 0.6 1.1 48.8 3.5 0.1 14.8 3.9 3.9 1.2 0.0 0.0 0.0 0.0 0.1 0.4 12.9 0.0 0.2 0.1 0.2 0.6 0.1 0.0 0.1 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.7 52.0 0.6 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 26.7 0.1 0.0 0.1 0.0 119.2 0.0 0.0 0.0 0.2 0.1 0.1 2.3 0.2 0.0 0.4 0.3 1.8 1.1 0.0 0.3 0.0 0.0 0.0 0.3 0.3 1.0 0.0 1.2 0.2 0.0 0.2 0.0 0.0 0.5 0.4 0.5 66.6 0.2 57.6 0.4 29.8 49.0 0.3 0.2 69.4 71.5 2.3 231.5 0.6 6.9 28.7 30.9 0.7 0.8 0.8 1.3 0.6 1.1 1.4 0.8 1.0 1.2 1.1 1.2 5.3 0.0 0.0 0.0 12.1 7.5 0.6 0.1 1.8 0.0 4.2 3.7 0.5 4.3 0.3 0.0 0.0 0.7 625.0 9.4 0.0 1.3 0.1 2.8 2.0 4.5 0.0 47.7 0.0 0.5 10.3 12.4 43.8 5.3 8.2 0.0 16.8 3.3 3.6 1.7 0.0 1.5 0.0 18.5 8.8 0.0 0.0 19.2 12.4 0.0 11.6 0.0 1299.7 0.0 0.0 0.1 5.8 0.0 82.7 3.8 8.1 1.4 0.5 0.0 0.0 0.5 3.9 0.0 1.3 1.0 4.4 1.9 527.4 0.0 2.1 3.8 CD80 "B7-1, B7.1, CD28LG, CD28LG1" ENSG00000121594 "CD80 molecule" P33681 3 119524293-119559614 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 3.0;lymphoid tissue: 6.8" "Group enriched" "Detected in some" 4 "Langerhans cells: 17.4;monocytes: 65.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.4;T-reg: 1.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 11.9;HDLM-2: 42.3;Karpas-707: 17.0;U-266/70: 7.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB025368, HPA050092" Enhanced "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "CAB025368: , HPA050092: AB_2681012" "unprognostic (2.36e-1)" "unprognostic (1.55e-2)" "unprognostic (5.91e-2)" "unprognostic (1.24e-1)" "unprognostic (3.14e-1)" "unprognostic (1.18e-1)" "unprognostic (1.86e-2)" "unprognostic (4.14e-3)" "unprognostic (1.02e-2)" "unprognostic (4.96e-3)" "unprognostic (1.16e-2)" "unprognostic (1.15e-1)" "unprognostic (9.03e-8)" "unprognostic (3.20e-1)" "unprognostic (3.65e-2)" "unprognostic (7.81e-3)" "unprognostic (1.94e-2)" 0.4 0.1 0.1 5.3 0.1 1.4 0.2 0.2 0.3 0.2 0.7 0.7 1.0 0.2 0.0 0.1 0.1 0.6 0.1 0.2 0.1 0.1 1.5 3.0 5.6 0.4 0.1 0.0 0.2 1.7 0.1 0.4 0.3 0.1 1.3 0.0 0.2 0.2 0.1 0.0 0.8 0.3 0.4 3.4 0.6 0.2 0.5 2.5 0.6 0.0 6.8 1.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 17.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 7.2 0.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.4 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 1.3 0.0 0.1 0.1 0.2 0.3 0.2 0.1 0.4 0.1 0.3 0.4 0.5 0.4 0.2 0.0 1.5 0.0 7.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.4 0.0 1.3 0.0 0.4 0.0 0.0 4.5 17.4 0.5 0.0 8.5 0.0 1.0 65.2 0.0 0.0 0.5 0.2 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 CD82 "IA4, KAI1, R2, ST6, TSPAN27" ENSG00000085117 "CD82 molecule" P27701 11 44564427-44620358 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 280.3;Proximal enterocytes: 220.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 536.4" "Group enriched" "Detected in all" 6 "B-cells: 310.1;granulocytes: 536.4;T-cells: 173.1" "Cell line enhanced" "Detected in many" "HMC-1: 463.8;U-87 MG: 323.3" "Region enhanced" "Detected in all" "white matter: 210.9" "Low region specificity" "Detected in all" "CAB002508, HPA028900, HPA061418" Supported Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "CAB002508: AB_563640, HPA028900: AB_10603558, HPA061418: AB_2684510" "unprognostic (5.31e-2)" "unprognostic (4.62e-1)" "unprognostic (2.38e-2)" "unprognostic (1.33e-1)" "unprognostic (2.79e-1)" "unprognostic (1.37e-2)" "unprognostic (1.78e-1)" "unprognostic (7.29e-2)" "unprognostic (3.48e-1)" "unprognostic (2.97e-1)" "unprognostic (2.58e-2)" "unprognostic (1.58e-1)" "unprognostic (3.48e-3)" "unprognostic (1.86e-3)" "unprognostic (2.33e-2)" "unprognostic (2.88e-2)" "unprognostic (6.30e-2)" 39.2 9.1 47.7 57.3 80.5 140.9 36.6 45.2 48.8 38.8 48.5 24.7 74.1 9.1 31.9 130.9 54.0 39.6 25.6 41.9 51.7 26.1 36.9 87.3 68.5 58.5 74.3 14.9 31.3 7.8 7.5 41.0 49.8 27.5 17.2 4.2 81.1 72.1 23.1 84.2 81.6 16.6 39.6 47.3 62.8 4.5 79.0 45.0 22.4 20.0 82.6 47.6 66.1 67.2 30.0 5.2 35.1 7.2 24.0 98.4 1.2 16.9 132.9 29.4 78.5 2.0 19.6 30.9 20.8 8.1 61.1 118.8 4.6 88.4 59.6 145.4 2.7 220.9 9.3 0.6 21.3 58.8 463.8 142.1 99.2 128.3 62.1 68.4 49.7 26.9 1.6 9.4 247.3 25.0 46.7 97.7 1.1 103.2 2.4 1.5 190.0 43.9 16.8 36.1 1.2 2.0 13.0 162.6 23.0 4.2 161.2 51.3 33.9 94.4 12.5 1.8 179.0 3.6 0.4 0.9 323.3 32.5 56.0 369.9 59.3 110.7 29.9 33.0 51.4 310.1 150.7 70.3 14.9 211.9 51.1 23.1 536.4 50.1 25.0 44.5 173.1 65.9 47.7 80.5 45.2 48.8 41.9 51.7 58.5 74.3 49.8 39.6 79.0 67.2 43.6 48.1 38.8 9.4 112.8 55.1 108.1 149.0 107.6 2.4 68.1 54.7 7.7 58.6 143.8 158.2 2.1 1.3 14.9 17.4 11.7 79.7 2.0 23.1 5.0 41.0 13.2 92.9 0.3 66.7 1.1 29.1 58.6 25.2 280.3 0.7 59.6 32.5 64.3 1.7 0.6 36.8 63.1 26.6 18.2 2.0 40.4 52.3 64.0 3.7 11.0 35.7 0.0 54.3 22.4 86.7 50.3 8.2 16.0 59.1 220.6 2.5 73.0 2.7 13.1 109.0 46.0 2.1 5.9 161.3 67.2 1.4 46.3 0.6 43.1 142.8 CD84 "hCD84, mCD84, SLAMF5" ENSG00000066294 "CD84 molecule" Q9UIB8 1 160541095-160579516 "CD markers, Predicted membrane proteins" "Adaptive immunity, Autophagy, Cell adhesion, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.2" "Cell type enhanced" "Detected in many" "granulocytes: 187.1;Hofbauer cells: 91.1;Kupffer cells: 177.0;Macrophages: 90.6;monocytes: 76.4;T-cells: 46.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 23.8;HEL: 45.3;HL-60: 13.1;HMC-1: 49.7;MOLT-4: 12.9;U-698: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063316, HPA068020, HPA070502" Enhanced Enhanced "Vesicles,Plasma membrane" NA NA 35000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" Vesicles "HPA063316: , HPA068020: , HPA070502: AB_2686274" "unprognostic (4.38e-2)" "unprognostic (6.16e-3)" "unprognostic (1.00e-2)" "unprognostic (8.16e-2)" "unprognostic (2.35e-1)" "unprognostic (2.00e-2)" "unprognostic (3.84e-1)" "unprognostic (2.54e-2)" "unprognostic (8.60e-2)" "unprognostic (1.80e-1)" "unprognostic (8.26e-2)" "unprognostic (1.57e-1)" "unprognostic (1.30e-2)" "unprognostic (2.15e-1)" "unprognostic (4.14e-2)" "unprognostic (1.24e-1)" "unprognostic (1.08e-1)" 3.3 2.4 1.9 19.4 2.1 7.9 2.7 2.3 2.4 2.8 1.9 3.2 2.4 1.4 0.9 2.2 1.1 6.2 1.4 1.7 1.9 0.8 5.2 7.8 24.2 5.2 3.1 1.5 2.0 0.9 0.4 7.1 4.5 1.1 4.5 0.2 1.4 3.4 0.4 1.3 4.6 4.0 3.8 15.2 3.6 1.9 5.2 9.9 1.1 0.7 13.2 4.7 0.8 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 45.3 0.1 0.0 0.0 13.1 49.7 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.9 0.1 0.0 0.0 12.9 9.7 0.0 0.0 0.0 0.4 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 30.8 0.0 2.9 0.0 32.7 9.6 15.0 8.2 8.0 6.5 6.3 7.0 10.1 7.1 6.0 4.0 7.4 1.2 1.4 3.2 4.1 10.5 8.8 1.9 2.1 2.3 2.4 1.7 1.9 5.2 3.1 4.5 3.8 5.2 7.2 1.3 0.0 6.4 0.0 27.4 2.4 0.7 0.0 0.6 0.2 0.6 1.5 1.2 2.8 1.3 0.0 0.0 0.5 20.5 0.2 0.0 0.1 0.9 0.5 0.2 4.2 0.0 21.5 0.1 0.2 0.5 1.2 2.6 0.2 187.1 0.1 3.3 1.1 91.1 0.0 0.2 0.1 0.0 177.0 42.2 1.5 0.6 90.6 5.4 34.7 76.4 0.0 4.1 0.0 0.1 0.0 0.0 0.0 10.8 0.9 0.3 0.3 0.7 0.2 0.0 1.6 1.5 0.1 0.4 0.5 2.4 1.0 46.8 2.9 0.2 0.6 CD86 "B7-2, B7.2, CD28LG2" ENSG00000114013 "CD86 molecule" P42081 3 122055362-122121139 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 34.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 121.3;Kupffer cells: 107.8;Langerhans cells: 148.3;Macrophages: 151.8;Microglial cells: 78.7;monocytes: 489.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 79.9;intermediate monocyte: 79.0;memory B-cell: 41.0;myeloid DC: 78.8;naive B-cell: 28.5;non-classical monocyte: 85.2" "Group enriched" "Detected in many" 18 "B-cells: 41.0;dendritic cells: 78.8;monocytes: 85.2" "Cell line enriched" "Detected in some" 7 "HDLM-2: 296.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004319, HPA026802" Approved Supported "Plasma membrane,Centriolar satellite" NA NA 160000 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "Centriolar satellite" "CAB004319: AB_627200, HPA026802: " "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (3.04e-2)" "unprognostic (3.52e-2)" "unprognostic (1.36e-1)" "unprognostic (2.79e-1)" "unprognostic (1.15e-1)" "unprognostic (8.56e-2)" "unprognostic (7.72e-3)" "unprognostic (1.21e-1)" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (9.72e-2)" "unprognostic (1.70e-2)" "unprognostic (9.78e-2)" "unprognostic (8.67e-2)" 7.8 5.3 3.5 34.5 3.4 10.3 4.4 4.0 3.6 3.5 4.8 6.3 3.7 2.4 1.0 4.0 2.1 14.3 2.7 3.2 6.1 1.9 11.2 18.6 28.8 7.2 5.5 2.1 2.6 2.9 1.1 15.0 7.0 2.4 7.7 0.9 2.3 2.5 0.8 2.0 6.8 7.4 5.3 23.4 5.2 3.1 5.0 10.6 1.3 0.8 22.0 14.9 1.0 10.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 40.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 296.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.5 0.2 0.0 0.0 0.2 0.0 32.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.4 0.0 0.1 0.0 0.1 15.1 0.6 35.1 0.0 0.9 0.0 0.1 79.9 0.8 0.0 79.0 0.0 41.0 0.2 0.3 78.8 28.5 0.2 0.1 0.9 3.7 85.2 8.3 1.6 33.4 3.5 3.4 4.0 3.6 3.2 6.1 7.2 5.5 7.0 5.3 5.0 10.2 0.9 0.0 7.7 0.3 36.5 3.6 0.1 1.3 0.0 0.0 0.4 1.3 0.3 1.5 3.2 1.8 0.0 1.8 3.3 0.0 0.0 0.2 3.7 0.1 0.0 2.6 0.0 1.3 0.2 3.5 0.8 0.8 0.5 0.0 2.5 0.1 1.8 0.8 121.3 0.0 0.3 0.0 0.0 107.8 148.3 2.7 0.0 151.8 7.2 78.7 489.4 0.0 0.0 0.5 0.1 0.3 0.0 0.0 20.6 0.3 0.0 0.1 0.1 0.4 0.0 0.3 0.7 0.2 0.3 0.2 4.0 1.9 2.1 0.1 0.0 0.3 CD8A CD8 ENSG00000153563 "CD8a molecule" P01732 2 86784610-86808396 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "lymphoid tissue: 369.0" "Group enriched" "Detected in many" 4 "dendritic cells: 111.7;T-cells: 242.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "MAIT T-cell: 234.4;memory CD8 T-cell: 523.0;naive CD8 T-cell: 476.8" "Lineage enriched" "Detected in many" 19 "T-cells: 523.0" "Cell line enhanced" "Detected in some" "JURKAT: 4.0;MOLT-4: 15.2;RPMI-8226: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000012, HPA037756, CAB075722" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 490000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB000012: AB_2075537, CAB075722: AB_2665709, HPA037756: AB_2675648" "unprognostic (1.29e-3)" "prognostic favorable (4.54e-4)" "unprognostic (9.26e-3)" "prognostic favorable (6.15e-6)" "unprognostic (7.28e-2)" "unprognostic (2.79e-3)" "unprognostic (1.03e-2)" "unprognostic (2.00e-2)" "unprognostic (1.35e-2)" "unprognostic (4.50e-3)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (1.36e-1)" "unprognostic (1.48e-1)" "unprognostic (6.74e-2)" "unprognostic (1.56e-2)" 5.3 4.6 2.1 21.2 2.8 22.5 4.7 1.9 3.0 3.8 1.4 4.9 11.8 3.0 3.6 4.4 4.0 9.8 2.3 2.1 2.1 1.8 7.4 10.5 45.0 2.8 2.1 2.5 2.6 1.1 1.5 0.6 2.5 3.4 5.9 0.2 8.3 1.9 0.8 1.3 20.7 2.4 2.2 117.1 16.4 1.0 2.3 369.0 4.4 0.4 21.4 9.1 4.0 2.1 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.0 1.4 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 4.0 0.0 0.2 0.0 0.6 15.2 0.9 0.5 0.1 0.2 0.1 0.7 3.3 0.0 0.3 0.7 1.9 0.1 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.5 0.1 0.0 0.1 0.2 0.7 0.0 0.0 0.0 1.4 0.8 0.3 30.0 0.3 234.4 0.6 2.3 523.0 0.4 0.6 2.2 476.8 4.3 27.9 0.9 1.2 0.8 152.4 2.1 2.8 1.9 3.0 2.1 2.1 2.8 2.1 2.5 2.2 2.3 2.1 2.2 0.0 4.6 0.0 5.7 2.0 0.2 0.0 0.0 0.3 1.5 1.5 3.4 1.5 0.6 0.0 0.0 0.0 111.7 0.2 0.0 0.2 0.3 0.5 0.3 1.3 0.0 7.8 4.2 0.0 0.0 2.6 8.2 0.4 2.5 0.0 6.4 2.3 0.1 0.0 3.1 0.3 0.0 1.9 11.5 0.2 0.0 6.6 0.0 1.0 5.9 0.1 38.1 0.0 0.2 0.0 0.0 0.0 30.8 0.2 0.0 0.4 1.5 0.4 0.0 1.1 1.4 0.4 0.4 1.1 1.8 0.1 242.4 0.0 0.6 0.1 CD8B CD8B1 ENSG00000172116 "CD8b molecule" P10966 2 86815339-86861924 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "lymphoid tissue: 459.6" "Group enriched" "Detected in many" 8 "dendritic cells: 53.2;T-cells: 162.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "memory CD8 T-cell: 601.8;naive CD8 T-cell: 1053.9" "Lineage enriched" "Detected in all" 25 "T-cells: 1053.9" "Cell line enriched" "Detected in some" 60 "RPMI-8226: 1113.4" "CAB004353, HPA029164" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "CAB004353: AB_627211, HPA029164: AB_2672936" "unprognostic (1.83e-3)" "unprognostic (1.98e-3)" "unprognostic (2.22e-2)" "prognostic favorable (7.88e-7)" "unprognostic (6.23e-2)" "unprognostic (7.05e-3)" "unprognostic (1.11e-2)" "unprognostic (2.59e-2)" "unprognostic (5.50e-3)" "unprognostic (5.91e-2)" "unprognostic (9.25e-2)" "unprognostic (4.60e-1)" "prognostic unfavorable (7.11e-6)" "unprognostic (7.84e-2)" "unprognostic (3.00e-1)" "unprognostic (1.86e-2)" "unprognostic (4.33e-2)" 1.9 1.9 0.4 10.6 0.3 8.3 2.9 1.1 0.6 33.4 0.1 2.1 5.0 1.2 1.1 1.6 1.5 4.3 1.0 0.1 1.2 1.0 1.6 4.2 25.9 5.0 2.1 0.9 0.9 4.6 8.8 0.3 4.8 1.7 3.0 0.0 2.4 1.0 0.6 1.4 15.1 1.1 0.7 15.6 5.1 0.4 2.4 459.6 2.0 0.4 15.1 3.4 1.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.1 0.2 0.0 1113.4 0.0 0.0 0.3 0.1 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 6.6 0.0 0.0 0.0 42.0 1.0 0.8 15.7 1.1 79.3 0.7 1.9 601.8 0.6 1.2 4.6 1053.9 6.1 1.1 1.7 1.0 2.2 427.6 0.4 0.3 1.1 0.6 0.1 1.2 5.0 2.1 4.8 0.7 2.4 0.5 1.3 6.4 5.5 0.0 4.4 4.0 2.2 0.0 0.6 0.0 2.2 2.8 1.0 1.5 0.0 0.0 0.0 0.1 53.2 0.1 0.0 0.1 0.5 0.2 0.5 0.7 0.0 1.7 0.4 0.0 0.0 2.0 7.1 0.2 0.0 0.0 0.7 0.5 0.1 0.0 0.5 4.6 0.0 4.0 4.3 0.5 0.0 4.1 5.4 5.6 7.5 0.0 10.3 0.0 0.1 0.0 0.1 0.0 10.8 0.7 12.4 0.2 0.0 0.0 0.0 2.0 1.2 0.2 0.1 0.5 2.8 0.0 162.9 0.0 7.5 0.3 CD93 "C1qR(P), C1QR1, C1qRP, CDw93, dJ737E23.1, ECSM3, MXRA4" ENSG00000125810 "CD93 molecule" Q9NPY3 20 23079360-23086324 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 137.6" "Cell type enhanced" "Detected in many" "Adipocytes: 321.5;Endothelial cells: 309.2;Hepatic stellate cells: 162.8;Kupffer cells: 156.4;Macrophages: 102.4;monocytes: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "classical monocyte: 25.8;intermediate monocyte: 16.8;myeloid DC: 9.1;neutrophil: 27.8;non-classical monocyte: 7.5" "Group enriched" "Detected in many" 41 "dendritic cells: 9.1;granulocytes: 27.8;monocytes: 25.8" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 346.0;TIME: 442.2;U-937: 593.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009300, HPA012368" Enhanced Approved "Vesicles,Plasma membrane" NA NA 550000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 32: U-937 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" "HPA009300: AB_1846342, HPA012368: AB_1846341" "unprognostic (2.05e-1)" "unprognostic (2.85e-1)" "unprognostic (1.07e-1)" "unprognostic (4.83e-2)" "unprognostic (2.31e-1)" "unprognostic (2.66e-2)" "unprognostic (6.45e-2)" "unprognostic (2.77e-1)" "unprognostic (4.51e-1)" "unprognostic (3.74e-2)" "unprognostic (2.61e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (2.74e-4)" "unprognostic (8.81e-3)" "unprognostic (6.13e-2)" "unprognostic (4.49e-2)" "unprognostic (3.11e-2)" 81.4 11.9 2.7 43.5 2.6 16.4 41.0 2.8 6.5 23.9 6.5 13.8 9.8 17.8 6.1 19.0 23.4 39.7 34.3 2.7 3.5 25.6 16.3 64.6 14.0 5.4 4.3 6.2 13.2 10.8 6.6 137.6 5.4 11.3 12.1 1.4 9.7 10.9 24.2 12.2 14.5 43.5 4.0 23.4 13.0 4.6 7.1 9.3 21.4 34.4 10.6 41.3 12.8 3.5 0.2 0.0 4.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 346.0 0.0 0.9 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.9 0.2 27.8 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 105.3 442.2 0.0 0.1 0.1 0.5 0.0 0.0 0.3 0.0 593.5 0.1 0.0 25.8 0.4 0.3 16.8 0.0 0.0 0.2 0.1 9.1 0.0 0.0 0.0 27.8 0.1 7.5 1.2 0.5 9.9 2.7 2.6 2.8 6.5 2.7 3.5 5.4 4.3 5.4 4.0 7.1 3.5 321.5 3.2 7.4 0.0 2.4 15.0 1.0 0.0 6.2 0.0 1.0 1.8 14.3 5.7 3.7 0.0 0.0 0.2 5.0 0.0 0.0 0.5 0.4 0.4 0.7 309.2 0.0 1.3 0.0 0.0 0.5 9.8 0.5 0.4 5.1 0.0 162.8 1.9 19.9 0.0 0.2 0.0 0.0 156.4 52.5 0.8 1.8 102.4 8.8 4.7 131.8 0.2 6.2 0.0 0.1 0.1 0.0 27.8 2.1 4.1 0.0 0.3 3.0 0.1 19.7 5.7 8.0 0.0 0.2 1.6 10.1 0.4 2.4 3.0 0.0 4.0 CD96 TACTILE ENSG00000153283 "CD96 molecule" P40200 3 111292719-111665750 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 61.8" "Group enriched" "Detected in many" 4 "dendritic cells: 96.8;NK-cells: 58.7;T-cells: 199.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 74.0;MAIT T-cell: 117.2;memory CD4 T-cell: 67.0;memory CD8 T-cell: 85.3;naive CD4 T-cell: 68.7;naive CD8 T-cell: 81.8;NK-cell: 79.5;T-reg: 47.4" "Group enriched" "Detected in many" 5 "NK-cells: 79.5;T-cells: 117.2" "Cell line enhanced" "Detected in some" "HEL: 15.9;JURKAT: 18.2;MOLT-4: 68.7;RT4: 58.2;U-937: 59.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA066754 Enhanced NA NA 85000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA066754: AB_2685714" "unprognostic (1.06e-3)" "unprognostic (3.95e-3)" "unprognostic (4.16e-3)" "unprognostic (1.91e-5)" "unprognostic (4.72e-3)" "prognostic favorable (5.52e-4)" "unprognostic (2.12e-2)" "unprognostic (3.48e-2)" "unprognostic (6.06e-2)" "unprognostic (4.84e-3)" "unprognostic (2.44e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (2.02e-6)" "unprognostic (3.12e-1)" "unprognostic (4.42e-2)" "unprognostic (3.90e-2)" "prognostic favorable (5.23e-5)" 5.2 1.7 0.7 12.2 0.8 16.0 2.8 1.2 1.0 3.1 1.8 5.0 6.0 2.6 0.9 1.8 1.9 5.8 0.8 0.8 0.8 1.6 3.7 8.3 26.9 1.8 0.7 0.9 0.4 0.2 0.7 1.0 1.2 2.1 5.9 0.1 2.7 1.1 0.4 1.0 10.1 1.4 0.7 12.8 6.8 0.8 1.2 61.8 3.9 0.1 20.2 11.8 2.6 2.2 0.1 0.0 0.2 0.1 0.2 0.0 0.8 0.0 0.1 0.0 0.0 0.3 1.6 0.3 0.3 0.0 0.0 0.7 0.1 0.1 0.0 0.2 0.0 15.9 0.2 0.2 0.0 0.8 1.3 0.0 0.0 0.1 0.1 1.2 0.0 18.2 0.3 2.0 0.0 0.0 68.7 0.2 0.6 0.0 0.0 0.1 1.9 0.5 0.6 58.2 0.1 0.0 0.2 0.9 0.1 0.3 0.3 0.2 0.0 0.3 1.1 0.3 0.1 5.6 1.9 0.0 0.3 59.0 12.2 2.3 0.5 15.6 74.0 0.3 117.2 10.8 67.0 85.3 0.3 18.8 68.7 81.8 2.7 79.5 0.7 0.5 47.4 46.4 0.7 0.8 1.2 1.0 0.8 0.8 1.8 0.7 1.2 0.7 1.2 2.2 1.5 19.2 19.0 0.0 12.5 3.2 0.8 0.1 1.2 1.6 1.6 1.4 1.0 0.0 9.3 1.8 0.0 0.6 96.8 0.8 0.0 0.1 0.8 2.1 0.8 3.0 0.0 9.3 0.7 0.0 0.2 4.3 8.6 1.6 16.4 0.4 2.2 0.9 0.2 0.0 0.4 0.7 0.0 5.0 6.7 1.1 0.3 6.7 3.6 6.5 2.9 0.5 58.7 0.0 0.1 0.0 1.3 0.0 29.6 0.3 0.0 0.4 1.7 2.1 0.0 0.8 1.0 0.4 0.7 0.6 3.1 1.9 199.9 0.2 0.5 0.6 CDH5 "7B4, CD144" ENSG00000179776 "Cadherin 5" P33151 16 66366622-66404784 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 235.9" "Cell type enhanced" "Detected in many" "Adipocytes: 311.9;Endothelial cells: 206.1;Hepatic stellate cells: 185.6;Late spermatids: 84.6;Syncytiotrophoblasts: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 752.5;TIME: 655.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB028366, HPA075875" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane" NA NA 1300000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Nuclear membrane" "CAB028366: AB_2276033, HPA075875: " "unprognostic (1.05e-1)" "unprognostic (8.13e-2)" "unprognostic (6.11e-2)" "unprognostic (4.89e-2)" "unprognostic (4.96e-2)" "unprognostic (5.50e-3)" "unprognostic (9.38e-2)" "unprognostic (5.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "unprognostic (2.33e-2)" "unprognostic (2.32e-1)" "prognostic unfavorable (5.14e-4)" "unprognostic (9.49e-3)" "unprognostic (3.01e-2)" "unprognostic (2.22e-1)" "unprognostic (3.15e-2)" 84.5 13.8 16.3 14.9 15.9 0.2 71.4 15.1 16.6 16.2 11.3 16.8 7.9 19.9 8.6 12.4 17.1 29.7 84.4 13.8 14.6 19.1 24.0 95.0 13.1 16.7 16.6 8.1 7.7 10.3 7.4 235.9 17.9 11.6 10.2 1.3 12.0 9.1 41.8 16.7 17.0 27.8 15.5 20.4 13.3 10.5 22.6 5.2 37.5 58.9 7.9 22.1 14.2 15.5 0.5 0.6 4.6 0.0 0.0 0.0 47.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 119.8 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 752.5 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.1 0.1 0.0 15.7 0.0 2.4 0.0 0.1 655.1 0.0 0.9 0.1 0.0 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.3 15.9 15.1 16.6 13.8 14.6 16.7 16.6 17.9 15.5 22.6 15.5 311.9 0.0 6.2 1.3 0.7 4.1 0.0 0.0 1.8 0.0 1.0 2.7 17.9 5.7 0.6 1.8 0.0 6.6 0.5 0.0 0.0 0.2 33.5 0.5 0.6 206.1 0.0 10.7 0.1 0.0 48.9 7.1 0.0 1.3 3.8 0.0 185.6 1.7 2.3 0.0 0.1 0.0 0.0 35.7 6.3 84.6 6.2 1.2 12.4 28.1 0.1 0.3 0.0 0.5 0.1 0.0 0.0 2.6 2.5 0.1 0.0 0.0 0.0 0.0 0.0 5.0 5.4 10.9 0.3 0.3 3.0 80.7 1.5 3.0 0.1 0.2 CDKN2D "INK4D, p19" ENSG00000129355 "Cyclin dependent kinase inhibitor 2D" P55273 19 10566460-10569059 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 283.7" "Cell type enhanced" "Detected in all" "dendritic cells: 146.8;Erythroid cells: 116.6;Macrophages: 105.4;NK-cells: 155.5;Spermatocytes: 126.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 90.6;MOLT-4: 113.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011201, HPA043546" Enhanced Supported Nucleoplasm,Cytosol NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm Cytosol "CAB011201: AB_261049, HPA043546: AB_2678545" "unprognostic (3.08e-1)" "prognostic favorable (1.02e-4)" "unprognostic (3.57e-2)" "unprognostic (1.49e-2)" "unprognostic (3.29e-2)" "unprognostic (1.37e-2)" "prognostic unfavorable (4.82e-4)" "unprognostic (2.08e-1)" "unprognostic (1.08e-2)" "unprognostic (6.55e-2)" "unprognostic (3.28e-1)" "unprognostic (1.50e-1)" "unprognostic (3.27e-3)" "unprognostic (9.90e-2)" "unprognostic (4.52e-1)" "unprognostic (4.43e-2)" "unprognostic (1.40e-1)" 13.7 9.8 61.0 13.3 64.9 283.7 9.5 43.9 86.9 9.4 37.3 14.2 6.3 7.0 3.1 14.3 11.0 6.4 18.8 64.8 59.7 11.3 7.1 30.8 23.9 53.8 51.5 7.1 5.8 3.3 15.7 8.2 59.9 8.0 5.6 16.3 7.3 4.1 19.7 18.1 14.5 7.8 46.1 42.4 9.4 38.6 57.6 78.0 6.2 15.9 16.1 11.2 12.9 57.4 30.8 4.8 15.1 10.0 8.0 12.2 3.8 19.8 23.2 21.4 18.8 6.1 7.3 8.5 6.4 21.1 21.6 6.4 5.2 5.1 7.7 34.3 12.6 90.6 5.8 10.2 9.2 9.2 70.2 5.1 16.2 11.0 8.2 17.7 6.1 52.6 3.8 72.3 21.5 4.3 113.9 48.3 3.0 23.4 22.7 18.4 14.7 5.1 9.7 2.6 21.3 11.2 14.0 10.4 15.2 2.8 9.4 24.0 4.7 25.2 12.9 42.1 30.1 44.9 16.5 15.8 26.7 15.5 18.4 143.5 17.7 79.7 30.2 23.2 24.2 56.7 24.9 34.1 17.4 50.0 23.3 27.4 139.9 41.1 35.6 51.0 22.5 31.8 61.0 64.9 43.9 86.9 64.8 59.7 53.8 51.5 59.9 46.1 57.6 57.4 35.2 6.4 7.0 4.6 65.2 23.2 13.7 17.1 38.7 32.4 11.1 15.2 9.2 5.7 8.2 5.5 12.5 4.8 146.8 11.8 9.8 7.7 21.2 26.9 10.2 29.3 7.2 116.6 18.5 4.9 8.4 11.0 3.6 16.7 21.0 4.8 26.7 3.8 10.4 47.1 14.8 6.4 36.7 42.2 47.7 13.7 7.2 105.4 30.2 1.9 46.4 22.2 155.5 1.0 8.2 14.2 9.4 6.0 9.2 11.4 5.0 5.1 10.9 37.1 19.7 8.3 25.8 126.0 83.7 38.6 33.1 4.9 63.4 4.5 6.9 23.8 CDO1 ENSG00000129596 "Cysteine dioxygenase type 1" Q16878 5 115804733-115816659 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 506.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 329.4;Hepatocytes: 149.5;Leydig cells: 91.0;Syncytiotrophoblasts: 481.9;Theca cells: 104.7" "Group enriched" "Detected in many" 6 "glioma: 33.6;liver cancer: 74.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.5" "Lineage enriched" "Detected in single" 15 "T-cells: 1.5" "Cell line enhanced" "Detected in many" "AF22: 48.1;ASC diff: 57.9;ASC TERT1: 22.3;GAMG: 17.2;HAP1: 17.1;NTERA-2: 17.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036573, HPA057503" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm Cytosol "HPA036573: AB_10696658, HPA057503: AB_2683451" "unprognostic (2.34e-2)" "unprognostic (3.31e-2)" "unprognostic (1.45e-2)" "unprognostic (2.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.32e-1)" "prognostic favorable (1.91e-5)" "unprognostic (1.14e-3)" "unprognostic (2.63e-1)" "unprognostic (7.23e-2)" "unprognostic (9.28e-3)" "unprognostic (6.69e-2)" "unprognostic (1.58e-1)" "unprognostic (2.74e-3)" "unprognostic (3.06e-2)" "unprognostic (3.70e-1)" "unprognostic (2.06e-2)" 119.3 18.1 26.1 3.3 28.2 0.2 35.9 24.6 31.2 9.5 109.8 4.8 0.7 8.3 140.3 3.5 13.7 10.5 26.1 28.3 30.7 3.1 506.7 11.7 6.6 23.6 26.2 25.8 14.2 0.7 20.7 35.2 25.6 9.1 1.8 15.9 7.2 72.8 8.5 3.0 4.0 6.2 25.6 3.7 4.1 15.6 26.7 1.3 9.6 19.9 3.1 8.1 5.7 25.6 0.0 0.0 48.1 0.0 57.9 22.3 0.2 1.4 0.4 4.6 4.5 0.0 0.0 0.0 0.0 0.6 17.2 0.1 17.1 0.0 6.6 0.1 8.5 1.7 0.0 1.4 0.2 0.1 0.0 8.5 0.0 0.7 0.0 1.2 6.3 0.0 0.0 0.0 5.5 0.0 1.2 0.2 17.8 0.0 0.0 0.0 3.2 0.1 0.0 0.0 0.0 11.0 0.1 0.0 0.0 4.0 0.0 5.4 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 26.1 28.2 24.6 31.2 28.3 30.7 23.6 26.2 25.6 25.6 26.7 25.6 4.1 0.0 1.3 6.8 0.7 0.8 0.8 0.0 0.6 27.3 1.0 7.1 3.4 0.0 0.0 1.8 6.2 329.4 0.3 0.0 0.0 9.9 6.0 0.3 7.1 3.1 1.8 2.7 12.2 0.2 17.0 27.8 0.0 0.3 0.0 7.5 33.9 149.5 23.4 1.7 16.4 0.0 0.0 5.7 1.6 15.0 91.0 0.6 1.8 1.0 0.6 31.4 0.0 5.5 3.1 0.3 0.0 37.6 0.0 0.9 0.0 2.0 0.0 3.8 13.1 7.3 3.9 1.6 1.4 0.5 1.3 481.9 0.9 104.7 0.0 0.1 CDR2L HUMPPA ENSG00000109089 "Cerebellar degeneration related protein 2 like" Q86X02 17 74987632-75005800 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.1" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 23.2;Glandular and luminal cells: 28.9;Late spermatids: 30.9;Pancreatic endocrine cells: 26.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-BR-3: 61.8;U-138 MG: 62.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022015 Enhanced Approved Cytosol NA NA "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 44: Endometrium - Transcription" Cytosol "HPA022015: AB_1846462" "unprognostic (4.60e-2)" "unprognostic (2.52e-1)" "unprognostic (1.20e-2)" "unprognostic (3.85e-2)" "unprognostic (2.17e-1)" "unprognostic (7.36e-3)" "unprognostic (9.22e-2)" "unprognostic (1.78e-2)" "unprognostic (9.11e-2)" "unprognostic (2.11e-1)" "unprognostic (4.21e-2)" "unprognostic (1.84e-1)" "unprognostic (5.89e-2)" "unprognostic (1.15e-1)" "unprognostic (1.20e-1)" "unprognostic (1.13e-1)" "unprognostic (1.33e-1)" 9.0 5.9 17.7 2.7 34.2 0.1 8.0 40.8 21.7 10.3 19.4 10.5 22.4 12.7 0.9 6.7 6.8 8.8 19.6 14.9 25.2 16.5 1.5 12.9 0.9 42.2 33.9 3.2 4.3 2.6 6.0 7.0 38.6 7.4 1.4 1.7 8.3 5.1 2.1 4.6 11.5 5.4 28.4 1.8 15.1 7.8 35.5 0.5 4.7 3.2 0.7 9.5 6.9 45.1 15.0 42.1 9.2 19.3 15.8 13.8 4.2 21.3 9.4 12.2 15.5 25.1 13.5 0.0 21.9 37.3 11.0 39.2 11.0 5.2 8.0 0.3 18.6 0.1 26.2 16.3 9.1 1.7 0.7 8.1 8.1 29.0 3.0 8.7 26.5 3.2 6.5 2.1 13.0 13.5 2.0 1.6 12.0 35.3 20.6 6.9 14.0 6.5 32.5 9.3 15.8 53.4 26.8 61.8 2.0 5.5 17.1 2.8 19.0 62.4 13.1 39.7 13.6 2.0 1.3 0.0 17.3 5.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 17.7 34.2 40.8 21.7 14.9 25.2 42.2 33.9 38.6 28.4 35.5 45.1 9.4 16.0 0.0 0.7 0.0 6.0 2.1 2.3 4.6 3.9 7.3 5.8 4.1 11.5 3.4 5.5 0.0 2.9 0.8 0.3 15.6 12.9 7.5 23.2 12.8 12.5 4.9 0.0 2.6 6.9 0.5 6.8 14.8 28.9 0.0 0.7 7.9 0.4 1.6 0.0 5.3 4.2 2.0 0.6 4.6 30.9 2.8 1.6 1.8 5.6 0.6 0.9 0.0 2.5 16.8 26.0 0.0 2.6 0.4 8.1 19.5 2.7 4.0 2.5 0.0 4.2 6.8 3.1 1.7 2.6 2.4 2.3 0.5 1.6 2.3 14.1 CEP135 "CEP4, FLJ13621, KIAA0635" ENSG00000174799 "Centrosomal protein 135" Q66GS9 4 55948871-56033361 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Early spermatids: 92.3;monocytes: 64.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (2.75e-1)" "unprognostic (2.71e-2)" "unprognostic (2.48e-2)" "unprognostic (1.06e-2)" "unprognostic (3.63e-1)" "unprognostic (3.42e-2)" "unprognostic (4.65e-3)" "unprognostic (4.78e-3)" "unprognostic (1.83e-3)" "unprognostic (9.89e-3)" "unprognostic (9.50e-2)" "unprognostic (2.27e-1)" "unprognostic (6.02e-9)" "unprognostic (7.55e-2)" "unprognostic (5.54e-2)" "unprognostic (1.95e-1)" "prognostic favorable (6.11e-5)" 2.6 1.6 1.0 7.2 1.3 10.1 2.8 2.1 1.6 3.5 1.9 2.4 3.1 7.6 2.1 2.0 3.3 3.1 1.4 1.2 1.3 4.0 1.3 3.2 10.2 1.7 1.5 5.0 1.7 2.0 1.2 5.9 1.7 2.3 3.2 3.7 1.5 1.6 0.8 3.9 3.3 5.0 1.0 5.7 2.2 6.4 2.0 9.5 2.6 1.3 7.6 2.9 2.2 1.9 8.9 4.8 13.0 12.3 2.6 5.0 5.5 8.6 6.1 7.7 9.0 5.2 9.0 23.7 6.4 3.8 6.0 4.0 13.8 5.2 14.6 6.5 8.4 8.3 7.6 4.9 2.9 15.2 12.6 3.9 4.1 9.9 7.0 3.4 6.5 11.9 15.4 11.0 8.1 5.2 21.3 9.5 8.3 4.4 4.9 15.4 6.1 4.8 5.6 6.4 9.3 9.6 7.7 5.2 6.4 7.8 6.9 9.7 6.5 10.4 17.0 12.5 15.1 5.9 4.4 15.7 5.2 11.8 13.1 9.9 2.1 2.9 3.0 2.8 2.8 3.0 3.9 2.9 1.5 5.6 5.0 3.1 4.3 4.7 3.2 5.6 2.7 1.4 1.0 1.3 2.1 1.6 1.2 1.3 1.7 1.5 1.7 1.0 2.0 1.9 16.3 6.4 12.4 7.8 30.2 9.1 8.2 6.3 7.4 12.6 5.6 6.6 8.5 2.8 9.4 7.3 10.4 20.0 27.3 5.2 3.9 9.4 92.3 23.1 14.6 18.2 5.4 28.2 10.0 5.4 16.3 11.5 3.1 13.0 14.5 38.2 12.5 1.7 10.4 26.9 10.4 5.5 6.1 12.9 11.3 19.4 5.9 19.2 5.4 19.7 64.5 4.3 32.0 8.0 13.9 15.6 6.7 8.2 16.7 5.2 3.0 10.0 17.4 24.5 6.6 16.2 11.2 57.3 38.7 6.8 6.7 9.6 20.0 34.6 5.7 6.3 CEP55 "C10orf3, CT111, FLJ10540" ENSG00000138180 "Centrosomal protein 55" Q53EZ4 10 93496612-93529092 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.4;testis: 21.7" "Cell type enhanced" "Detected in many" "Early spermatids: 29.4;Extravillous trophoblasts: 17.1;Granulosa cells: 19.8;Spermatocytes: 77.3;Spermatogonia: 17.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 8 "T-reg: 1.3" "Lineage enriched" "Detected in single" 14 "T-cells: 1.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA023430 Approved Approved "Plasma membrane,Midbody,Centriolar satellite" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Centriolar satellite" Midbody "HPA023430: AB_10960212" "unprognostic (9.85e-2)" "unprognostic (1.12e-2)" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" "unprognostic (5.15e-2)" "unprognostic (4.26e-2)" "prognostic unfavorable (3.20e-9)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.50e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.66e-5)" "unprognostic (3.99e-2)" "prognostic unfavorable (0.00e+0)" "prognostic favorable (3.15e-4)" "unprognostic (7.86e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" 1.3 0.6 0.0 7.6 0.0 5.0 1.4 0.0 0.2 1.7 0.0 7.0 6.7 1.4 0.1 7.3 0.4 1.4 0.3 0.0 0.1 0.3 0.6 1.3 14.7 0.1 0.3 0.2 0.2 0.2 0.3 3.5 0.2 0.3 8.8 0.0 1.2 0.3 0.1 4.5 6.3 5.2 0.0 2.4 4.6 21.7 0.4 27.4 0.5 0.2 15.5 3.1 2.3 0.1 208.5 81.5 53.0 67.7 5.8 12.0 29.6 112.4 78.2 103.5 106.4 87.2 108.6 55.4 48.2 72.8 69.6 115.4 64.8 54.8 123.4 167.2 33.7 21.0 49.2 29.9 0.6 36.3 46.3 2.8 3.8 110.6 133.5 30.7 97.1 89.9 19.3 101.8 118.5 48.3 96.3 54.8 20.9 64.2 58.8 41.3 86.9 30.3 47.1 25.5 21.7 30.7 86.3 26.3 64.9 40.1 68.9 36.4 61.4 65.3 90.6 90.5 186.7 45.1 66.1 66.8 51.0 134.8 59.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.3 0.2 0.0 0.4 0.1 0.2 0.0 1.3 0.0 2.7 3.6 0.9 1.9 0.0 0.0 1.8 2.0 0.4 2.8 0.2 0.0 0.0 7.7 0.9 3.3 0.0 0.6 29.4 1.7 2.0 1.5 0.0 2.5 0.5 0.2 17.1 2.3 8.2 3.6 0.0 19.8 2.2 0.3 12.9 0.0 0.3 4.5 4.1 7.0 5.1 8.2 0.3 5.1 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.3 0.0 0.4 14.8 1.1 0.4 0.0 0.2 0.0 0.0 0.5 4.5 77.3 17.3 16.1 1.3 1.5 4.3 1.6 7.9 1.7 CEP89 "CCDC123, FLJ14640" ENSG00000121289 "Centrosomal protein 89" Q96ST8 19 32875925-32971991 "Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039382, HPA040056" Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Plasma membrane" "HPA039382: AB_2676479, HPA040056: AB_10671048" "unprognostic (4.23e-2)" "unprognostic (7.50e-3)" "unprognostic (1.97e-1)" "unprognostic (1.53e-3)" "unprognostic (1.30e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (8.78e-5)" "unprognostic (1.12e-1)" "unprognostic (4.55e-2)" "unprognostic (3.04e-2)" "unprognostic (1.80e-2)" "unprognostic (4.00e-2)" "unprognostic (1.74e-1)" "unprognostic (4.48e-2)" "unprognostic (6.53e-2)" "unprognostic (3.03e-1)" "unprognostic (2.47e-2)" 6.0 6.0 6.3 5.3 6.7 4.7 6.4 7.7 6.4 9.1 7.7 8.9 4.0 9.8 6.7 6.3 8.9 5.1 6.2 6.6 6.9 8.6 3.3 5.7 6.0 5.8 5.6 10.1 6.1 7.0 9.3 5.3 4.7 12.5 4.4 7.4 6.7 5.9 5.9 6.6 6.7 6.9 4.0 6.4 6.2 4.2 7.3 6.2 7.5 4.3 4.3 8.0 6.8 6.0 19.1 25.7 17.1 14.7 9.1 11.0 9.9 14.7 9.8 25.5 19.4 9.3 11.2 7.6 7.8 15.1 14.4 10.5 16.9 11.9 17.6 20.2 10.4 5.9 18.5 8.9 7.2 8.3 5.7 13.3 16.2 24.1 16.2 10.4 19.5 10.4 9.2 11.0 12.3 14.2 9.4 6.4 7.3 10.4 8.0 10.4 9.2 6.6 11.9 10.3 24.1 17.7 15.1 10.3 8.8 10.3 7.7 6.7 12.6 18.4 16.1 16.0 15.3 5.3 9.1 7.0 15.8 7.8 14.0 12.8 3.1 1.6 2.7 4.6 4.9 3.3 2.9 2.4 1.8 5.7 2.8 3.3 3.7 2.1 2.4 3.7 3.4 1.7 6.3 6.7 7.7 6.4 6.6 6.9 5.8 5.6 4.7 4.0 7.3 6.0 12.7 28.9 16.0 17.3 9.5 5.1 11.5 14.5 8.0 16.3 11.7 11.8 17.5 10.0 19.0 20.2 18.8 9.3 9.6 8.0 11.7 19.1 15.1 49.2 24.9 14.8 9.7 13.3 17.2 16.6 11.2 17.7 10.7 17.3 17.1 21.1 14.6 5.6 11.8 20.2 13.6 9.7 8.2 5.3 5.1 8.5 16.1 8.9 5.4 14.0 9.8 9.6 10.3 9.5 15.9 15.1 5.2 12.8 5.4 6.7 9.9 16.3 48.3 38.6 0.0 17.5 16.1 20.3 13.8 7.5 4.5 4.2 9.0 12.7 8.6 6.6 CERCAM "CEECAM1, GLT25D3" ENSG00000167123 "Cerebral endothelial cell adhesion molecule" Q5T4B2 9 128411751-128437351 "Metabolic proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 551.5" "Cell type enriched" "Detected in many" 7 "Oligodendrocytes: 626.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 280.5;ASC TERT1: 284.1;fHDF/TERT166: 271.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021657, HPA051595" Uncertain Approved "Nucleoplasm,Nucleoli,Cell Junctions" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nucleoli" "Cell Junctions" "HPA021657: AB_1846507, HPA051595: AB_2681545" "unprognostic (2.87e-2)" "unprognostic (1.37e-3)" "unprognostic (1.89e-3)" "unprognostic (2.19e-1)" "unprognostic (4.68e-3)" "unprognostic (7.79e-3)" "unprognostic (3.29e-3)" "unprognostic (5.68e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (1.59e-1)" "unprognostic (5.93e-2)" "prognostic unfavorable (3.33e-16)" "unprognostic (1.34e-2)" "unprognostic (1.04e-1)" "unprognostic (6.05e-3)" "prognostic unfavorable (3.30e-5)" 26.1 8.9 249.9 12.3 411.3 2.5 24.5 248.6 378.3 42.4 140.1 20.9 7.9 35.0 9.7 13.1 23.4 31.2 34.0 261.5 322.7 25.9 3.7 16.9 4.1 344.1 349.4 31.2 30.1 31.0 106.4 49.4 323.9 27.9 7.7 1.0 21.4 22.8 7.0 15.0 12.3 47.4 224.7 10.9 15.8 11.1 386.4 2.4 23.4 7.0 3.9 29.9 30.8 551.5 44.7 26.0 35.2 38.2 280.5 284.1 27.4 145.5 149.7 41.2 32.0 10.3 2.4 0.0 58.3 271.9 33.5 33.8 14.7 22.2 13.9 11.7 25.6 2.9 24.1 15.5 89.7 5.4 84.4 171.6 11.7 48.4 10.5 157.7 44.3 3.0 13.0 36.5 51.8 82.3 2.3 55.7 1.8 2.3 25.4 4.7 23.6 7.3 18.4 15.5 4.9 8.5 33.8 43.1 16.7 10.1 34.4 13.7 48.2 103.5 27.3 138.1 23.2 42.2 35.0 0.8 99.7 17.1 21.0 0.1 0.6 0.0 1.8 0.7 0.1 0.1 0.1 2.1 0.7 0.0 0.0 2.3 0.0 0.6 0.0 1.0 0.0 1.3 249.9 411.3 248.6 378.3 261.5 322.7 344.1 349.4 323.9 224.7 386.4 551.5 8.5 6.4 10.3 7.2 3.5 8.9 6.5 7.0 10.8 1.7 8.7 6.9 3.9 0.0 13.6 11.0 0.0 18.4 5.8 0.0 0.0 11.6 2.7 3.1 18.7 7.7 0.0 2.5 2.9 3.4 61.1 82.3 3.6 6.7 8.8 9.8 16.8 0.1 6.2 6.7 3.3 0.0 2.0 0.8 10.4 2.3 24.2 2.9 40.9 3.7 1.3 0.1 17.5 11.6 626.9 4.5 0.0 26.4 17.9 5.0 0.0 0.9 3.9 0.9 6.6 27.8 26.4 8.6 22.2 2.4 4.1 19.6 3.3 5.9 0.0 2.8 CERS2 "FLJ10243, LASS2, SP260" ENSG00000143418 "Ceramide synthase 2" Q96G23 1 150960583-150975003 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 732.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 200.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027262, HPA078737" Approved Supported "Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 15: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 2: Hepatocytes - Metabolism" "Nuclear membrane, Endoplasmic reticulum" "HPA027262: AB_1852717, HPA078737: " "unprognostic (1.01e-1)" "unprognostic (2.70e-3)" "unprognostic (3.72e-2)" "unprognostic (1.29e-2)" "unprognostic (8.23e-2)" "unprognostic (2.03e-2)" "unprognostic (7.05e-2)" "unprognostic (1.60e-1)" "unprognostic (2.34e-1)" "unprognostic (4.05e-2)" "unprognostic (8.17e-3)" "unprognostic (1.11e-1)" "unprognostic (2.63e-2)" "unprognostic (1.56e-1)" "unprognostic (7.21e-2)" "unprognostic (1.09e-1)" "unprognostic (1.85e-1)" 95.0 307.2 126.3 53.1 171.3 80.1 100.1 170.2 165.7 96.8 141.7 81.5 94.5 79.9 89.6 46.2 94.1 97.1 71.8 125.5 144.8 261.4 732.2 135.0 56.4 201.5 168.5 104.4 129.3 159.4 84.7 113.8 192.1 83.2 88.6 38.1 61.5 82.7 37.5 46.9 102.8 99.2 158.7 65.1 128.0 49.8 157.2 67.5 161.4 57.3 69.9 91.0 70.7 223.7 154.3 175.8 138.1 277.9 395.1 237.1 100.8 153.1 217.9 278.1 189.1 188.4 248.5 137.7 244.3 242.4 174.6 165.5 195.5 160.7 247.6 194.0 157.7 193.4 107.5 219.3 277.6 216.4 218.5 214.0 197.9 254.3 315.6 341.4 174.3 189.8 210.4 281.0 363.4 255.6 134.2 135.7 200.9 499.4 299.6 160.0 95.4 208.4 311.5 127.2 121.7 185.8 169.6 278.7 183.8 172.1 335.6 296.5 145.4 196.4 93.6 180.1 267.9 189.5 229.0 841.7 222.4 91.0 200.7 212.1 80.2 136.0 76.9 43.7 93.6 34.6 70.3 78.8 69.5 31.9 60.6 60.1 86.5 63.4 32.8 70.1 86.7 88.5 126.3 171.3 170.2 165.7 125.5 144.8 201.5 168.5 192.1 158.7 157.2 223.7 46.3 67.3 67.9 8.8 23.1 24.1 38.2 37.0 18.2 7.5 52.8 27.6 2.8 120.1 23.2 53.3 4.2 77.8 40.2 60.7 13.7 104.6 7.5 24.9 39.9 47.9 24.6 24.8 5.5 92.8 42.4 44.2 16.3 29.7 36.8 33.0 38.9 200.5 55.9 3.3 5.9 29.3 30.5 45.2 35.2 7.9 56.2 54.5 37.4 5.6 39.4 26.5 26.8 7.5 51.3 103.7 32.4 40.3 29.2 52.4 98.8 81.7 21.2 9.9 39.5 37.2 33.8 13.8 6.8 13.9 15.6 54.2 34.3 39.0 29.1 34.2 CES1 "CEH, CES1A1, CES1A2, CES2, HMSE, HMSE1, SES1" ENSG00000198848 "Carboxylesterase 1" P23141 16 55802851-55833337 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "liver: 2517.1" "Group enriched" "Detected in many" 7 "Cholangiocytes: 613.4;Hepatocytes: 2420.8" "Cancer enriched" "Detected in all" 6 "liver cancer: 711.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 16 "classical monocyte: 109.6;myeloid DC: 114.5" "Group enriched" "Detected in many" 22 "dendritic cells: 114.5;monocytes: 109.6" "Group enriched" "Detected in some" 5 "Hep G2: 700.9;THP-1: 688.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012023, HPA046717" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" No NA 40000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum" "HPA012023: AB_1846554, HPA046717: AB_2679770" "unprognostic (1.04e-2)" "unprognostic (9.85e-2)" "unprognostic (2.94e-1)" "unprognostic (1.28e-1)" "unprognostic (1.55e-3)" "unprognostic (7.46e-3)" "unprognostic (1.51e-1)" "unprognostic (1.42e-1)" "unprognostic (3.51e-1)" "unprognostic (5.74e-2)" "unprognostic (4.62e-2)" "unprognostic (3.29e-2)" "unprognostic (1.91e-2)" "unprognostic (5.32e-2)" "unprognostic (1.92e-1)" "unprognostic (2.87e-1)" "prognostic unfavorable (9.92e-4)" 94.9 14.1 0.9 3.2 1.2 27.0 43.6 0.8 1.8 26.6 3.7 82.3 24.0 60.4 7.5 41.1 54.6 272.9 66.1 1.0 1.4 6.7 2517.1 167.8 1.8 2.3 1.2 20.3 8.8 0.7 3.7 8.5 1.5 39.2 12.3 2.9 41.4 36.4 5.2 14.0 27.4 40.4 1.0 41.0 56.1 7.8 1.1 2.5 9.9 9.4 1.0 57.7 17.7 1.1 0.7 4.4 0.0 0.0 90.8 0.6 3.1 0.3 0.0 0.0 0.0 43.5 0.0 0.0 19.4 0.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.9 700.9 0.0 1.3 0.1 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 40.8 0.1 0.6 0.0 0.0 1.5 6.7 0.0 0.5 0.0 0.1 3.2 0.1 1.1 0.9 0.0 688.0 0.1 0.0 0.4 0.2 0.5 2.2 0.1 1.0 0.0 151.7 0.0 0.0 109.6 0.5 4.5 6.1 1.5 1.1 0.7 5.0 114.5 1.2 0.7 1.1 0.6 0.3 1.6 6.8 0.4 58.0 0.9 1.2 0.8 1.8 1.0 1.4 2.3 1.2 1.5 1.0 1.1 1.1 2.0 16.0 67.6 0.0 11.3 16.7 5.3 6.8 1.2 0.0 1.2 8.1 0.8 613.4 31.5 16.5 0.0 0.5 12.2 0.1 0.0 15.4 79.6 1.0 10.6 8.9 37.5 177.7 0.0 18.7 2.2 57.4 1.1 0.2 6.3 0.0 66.0 2420.8 18.1 0.0 0.0 12.2 4.1 107.3 26.7 197.8 18.6 58.7 39.2 1.0 39.6 10.4 7.2 0.0 0.0 0.9 1.3 98.9 1.8 1.5 0.6 0.9 169.0 0.9 0.0 9.8 9.8 1.0 2.3 20.6 11.6 0.8 16.9 0.9 0.7 2.6 CES2 "CE-2, CES2A1, iCE" ENSG00000172831 "Carboxylesterase 2" O00748 16 66934444-66945096 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 703.3;liver: 345.7" "Cell type enhanced" "Detected in all" "Distal enterocytes: 794.4;Hepatocytes: 518.5;Paneth cells: 519.2;Proximal enterocytes: 2529.8;Undifferentiated cells: 499.5" "Cancer enhanced" "Detected in all" "liver cancer: 104.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "HPA018897, HPA074629" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 6400000 "Cluster 44: Non-specific - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" "Endoplasmic reticulum, Cytosol" "HPA018897: AB_1846558, HPA074629: " "unprognostic (8.15e-3)" "unprognostic (1.82e-2)" "unprognostic (1.32e-1)" "unprognostic (2.67e-3)" "unprognostic (2.74e-2)" "unprognostic (1.38e-1)" "unprognostic (5.80e-2)" "unprognostic (1.31e-1)" "unprognostic (6.93e-2)" "unprognostic (7.99e-2)" "unprognostic (1.73e-3)" "unprognostic (2.66e-2)" "prognostic favorable (1.50e-5)" "unprognostic (8.01e-2)" "unprognostic (1.53e-1)" "unprognostic (4.14e-2)" "unprognostic (1.38e-1)" 18.8 38.1 21.2 18.1 20.6 6.3 13.5 24.1 23.0 22.0 25.6 191.2 703.3 14.6 14.4 132.7 17.9 19.5 51.4 22.1 20.6 96.5 345.7 15.6 11.9 20.8 20.8 17.0 14.4 38.0 15.7 10.1 20.6 16.7 178.8 16.2 32.9 15.0 33.8 32.7 576.5 19.7 20.0 12.4 41.6 9.3 20.9 13.1 27.9 14.3 20.8 13.7 33.5 20.5 11.6 16.6 18.4 25.9 19.5 17.9 14.5 15.9 25.8 17.6 22.1 17.3 23.5 15.7 14.3 20.9 13.3 35.4 14.2 39.8 15.3 10.7 18.9 14.4 9.6 44.2 26.3 21.6 26.3 25.4 82.5 26.0 46.7 24.6 14.1 11.3 22.2 10.9 35.7 9.1 17.7 21.4 10.8 16.3 18.8 20.9 19.1 19.8 60.7 18.6 11.6 16.0 50.9 12.6 14.5 8.1 21.0 26.5 17.5 22.4 12.6 15.3 11.1 23.3 24.0 18.4 36.7 17.3 17.4 4.1 5.4 1.6 5.1 3.8 4.5 3.0 4.1 5.8 4.5 3.1 4.8 4.5 1.6 4.3 4.1 4.3 3.2 3.1 21.2 20.6 24.1 23.0 22.1 20.6 20.8 20.8 20.6 20.0 20.9 20.5 13.2 32.1 24.6 8.8 18.8 19.5 13.5 32.8 39.3 31.2 12.4 18.3 33.6 115.8 19.8 53.3 20.9 16.1 12.9 794.4 37.2 24.6 2.1 26.9 15.0 14.1 24.1 7.8 7.0 33.8 5.7 15.3 60.6 33.7 27.3 80.7 28.5 518.5 19.6 28.6 9.7 196.0 18.3 37.0 9.6 2.3 18.6 15.3 10.6 10.3 19.5 19.0 21.6 8.0 5.9 51.8 519.2 18.0 8.5 19.1 2529.8 176.0 85.4 24.2 32.9 19.5 15.2 47.2 19.7 116.1 20.5 13.5 13.0 22.1 499.5 16.7 CFAP251 "CaM-IP4, MGC33630, WDR66" ENSG00000158023 "Cilia and flagella associated protein 251" Q8TBY9 12 121918592-122003927 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 22.3;testis: 19.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.7;Fibroblasts: 1.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 1.6" "Lineage enriched" "Detected in single" 8 "dendritic cells: 1.6" "Cell line enhanced" "Detected in many" "HBEC3-KT: 31.8;hTCEpi: 30.8;hTERT-HME1: 19.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA039902, HPA040005" Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA039902: AB_10795236, HPA040005: AB_10795160" "unprognostic (4.92e-3)" "unprognostic (9.05e-2)" "unprognostic (7.99e-3)" "prognostic favorable (3.11e-4)" "unprognostic (5.58e-3)" "unprognostic (6.89e-3)" "unprognostic (1.44e-2)" "unprognostic (2.45e-1)" "unprognostic (2.89e-1)" "unprognostic (2.34e-1)" "unprognostic (7.72e-2)" "unprognostic (1.55e-1)" "unprognostic (2.43e-2)" "unprognostic (4.29e-2)" "unprognostic (1.37e-1)" "unprognostic (1.79e-2)" "unprognostic (1.35e-1)" 1.1 0.8 1.6 0.3 2.4 0.1 1.3 1.3 1.7 3.5 13.2 0.2 0.1 1.9 4.7 0.3 22.3 1.2 1.3 2.4 3.9 2.7 1.4 3.0 0.6 5.5 6.6 2.2 1.7 2.9 6.5 0.9 3.6 0.7 0.1 4.6 1.1 1.6 0.3 1.5 0.2 0.6 2.7 1.7 0.4 19.9 4.1 0.5 4.7 0.4 0.9 0.3 1.3 1.6 4.7 0.4 0.4 0.2 0.5 0.5 0.5 0.3 2.5 1.2 3.0 0.3 1.4 0.2 3.7 0.2 0.7 0.9 0.3 31.8 4.4 0.2 0.5 0.2 0.6 0.3 3.7 0.1 8.6 1.8 30.8 2.4 19.9 0.7 1.3 0.5 7.5 0.1 1.9 0.9 0.3 0.6 0.4 0.4 0.2 0.4 0.8 0.0 5.4 0.5 2.5 0.1 0.2 0.1 0.2 0.8 0.9 0.1 1.0 2.5 3.9 0.5 0.5 0.5 0.2 3.8 2.9 0.1 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.1 0.0 1.6 2.4 1.3 1.7 2.4 3.9 5.5 6.6 3.6 2.7 4.1 1.6 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 CFB "BF, BFD, H2-Bf" ENSG00000243649 "Complement factor B" P00751 6 31945650-31952084 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "liver: 2613.2" "Cell type enhanced" "Detected in many" "Ductal cells: 873.6;Exocrine glandular cells: 197.3;Hepatocytes: 284.0;Pancreatic endocrine cells: 318.0;Proximal enterocytes: 139.7" "Cancer enhanced" "Detected in all" "liver cancer: 78.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 15.0;ASC TERT1: 23.0;EFO-21: 25.1;fHDF/TERT166: 14.1;HSkMC: 19.1;U-87 MG: 10.1" "Low region specificity" "Detected in all" "HPA000951, HPA001817, HPA001832, CAB016381" Supported Approved "Endoplasmic reticulum,Vesicles,Cell Junctions" "Secreted to blood" NA NA 879000000 120000000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Endoplasmic reticulum, Vesicles" "Cell Junctions" "CAB016381: AB_627562, HPA000951: AB_2797216, HPA001817: AB_1078779, HPA001832: AB_1078778" "prognostic favorable (2.76e-5)" "unprognostic (1.02e-1)" "unprognostic (1.44e-1)" "unprognostic (7.94e-2)" "unprognostic (1.82e-2)" "unprognostic (8.56e-2)" "unprognostic (8.08e-3)" "unprognostic (8.81e-2)" "unprognostic (3.51e-1)" "unprognostic (2.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.57e-2)" "prognostic unfavorable (1.53e-5)" "unprognostic (1.36e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-2)" "unprognostic (3.68e-2)" 143.7 18.0 3.6 32.8 3.6 0.1 28.5 3.4 9.9 16.3 3.9 22.3 28.1 8.2 14.2 24.1 53.7 0.8 42.6 3.7 3.4 58.7 2613.2 39.2 4.2 4.1 3.7 9.9 51.8 0.2 17.7 5.0 3.8 60.3 14.5 1.4 43.3 0.0 3.0 7.7 73.1 48.3 3.4 12.9 54.5 2.1 3.7 1.9 15.5 0.7 6.7 17.8 9.2 3.6 0.5 1.9 0.1 0.0 15.0 23.0 0.1 0.0 0.2 1.1 0.0 0.1 8.6 0.1 25.1 14.1 0.6 6.0 0.0 1.8 1.2 1.0 0.3 0.7 0.4 0.5 0.0 1.0 0.4 19.1 0.4 0.6 0.5 1.3 0.2 0.1 0.3 0.7 0.1 0.2 0.1 0.3 0.4 0.0 0.4 0.3 0.3 1.3 1.7 0.5 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.2 0.0 3.4 1.2 0.4 0.4 0.7 2.1 1.0 10.1 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.6 3.6 3.4 9.9 3.7 3.4 4.1 3.7 3.8 3.4 3.7 3.6 1.0 0.0 16.9 0.0 2.6 0.8 0.9 64.8 11.4 0.3 4.9 0.9 0.4 44.3 127.3 5.5 0.0 0.1 0.0 3.7 3.9 873.6 0.0 1.9 0.4 3.9 2.4 16.0 0.2 197.3 0.2 34.6 20.9 1.2 0.0 0.0 11.7 284.0 1.0 0.0 0.2 8.5 18.3 19.7 1.0 0.0 2.8 1.1 0.0 5.6 18.1 0.4 0.0 0.0 0.0 318.0 10.6 0.0 0.1 8.6 139.7 17.1 75.4 0.7 0.0 1.0 12.6 0.1 0.1 3.9 1.8 1.6 1.6 0.0 12.4 4.5 CFD "ADN, DF, PFD" ENSG00000197766 "Complement factor D" P00746 19 859664-863641 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1496.7;breast: 993.2" "Group enriched" "Detected in many" 6 "Fibroblasts: 9365.5;Leydig cells: 5032.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 297.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 297.6" "Group enriched" "Detected in many" 5 "ASC diff: 197.4;THP-1: 342.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 732000000 4400000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.00e-2)" "unprognostic (6.09e-2)" "unprognostic (2.44e-1)" "unprognostic (1.22e-3)" "unprognostic (6.92e-2)" "unprognostic (5.28e-2)" "unprognostic (8.11e-3)" "unprognostic (2.48e-1)" "unprognostic (1.46e-2)" "unprognostic (8.10e-2)" "prognostic favorable (1.77e-4)" "unprognostic (9.53e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (1.23e-1)" "unprognostic (4.55e-2)" "unprognostic (1.92e-2)" "unprognostic (9.75e-2)" 1496.7 33.3 1.5 9.6 1.6 10.7 993.2 1.2 2.4 597.4 3.7 324.8 23.5 58.4 2.4 212.8 258.0 9.6 854.2 1.7 2.3 18.1 8.7 363.3 2.1 3.3 2.3 74.3 41.4 1.7 9.0 14.5 3.6 277.8 10.9 0.6 247.3 6.3 197.0 488.6 248.4 4.0 2.6 28.6 263.8 51.8 2.9 3.6 332.3 26.9 0.8 848.3 729.8 5.8 3.9 5.2 0.6 2.2 197.4 26.2 9.5 0.8 0.0 0.0 0.0 0.8 0.4 0.2 5.7 0.0 0.5 3.0 1.8 0.5 0.0 5.7 14.5 0.5 12.3 3.8 3.6 2.5 4.9 8.7 0.2 0.1 0.0 0.8 0.0 4.5 11.9 0.9 0.0 2.6 0.6 49.2 1.0 4.5 16.1 1.3 0.5 5.2 0.3 1.2 1.8 1.8 5.5 1.9 0.5 0.6 7.5 342.2 0.4 0.2 5.1 2.9 0.6 7.8 4.7 0.4 0.2 20.8 0.2 297.6 41.2 127.8 8.4 55.5 13.2 5.7 4.2 10.2 14.5 1.4 9.7 9.7 112.0 1.3 57.3 1.8 4.7 37.8 1.5 1.6 1.2 2.4 1.7 2.3 3.3 2.3 3.6 2.6 2.9 5.8 857.8 9.6 23.3 0.0 19.2 785.5 49.0 10.1 17.1 2.9 107.3 120.1 55.5 21.5 30.9 18.4 2.1 36.6 40.0 33.1 11.7 7.7 27.1 23.1 593.3 114.8 4.2 8.2 0.2 0.0 32.9 9365.5 113.6 15.9 17.1 0.9 30.4 2.6 272.4 1.7 0.4 8.7 0.0 424.7 1145.2 89.6 5032.4 442.5 642.1 4.7 303.6 1.3 21.6 0.0 0.1 2.9 64.8 283.2 41.0 19.7 4.3 3.4 28.4 6.5 0.0 414.3 530.2 11.4 21.3 28.6 735.9 34.3 82.8 1.2 21.0 233.2 CFHR1 "CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, H36-1, H36-2, HFL1, HFL2" ENSG00000244414 "Complement factor H related 1" Q03591 1 196819731-196832189 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 272 "liver: 2081.3" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 320.0" "Cancer enriched" "Detected in single" 798 "liver cancer: 182.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.0;HeLa: 1.2;HL-60: 2.0;U-266/70: 2.4" "Not detected" "Not detected" "HPA038915, HPA038922, HPA040726" Supported Approved Vesicles "Secreted to blood" NA NA 13000000000 "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA038915: AB_2676269, HPA038922: AB_2676271, HPA040726: AB_2677101" "unprognostic (2.28e-1)" "unprognostic (3.18e-1)" "unprognostic (3.50e-2)" "unprognostic (1.88e-2)" "prognostic favorable (8.71e-6)" "unprognostic (3.02e-1)" "unprognostic (3.70e-1)" "unprognostic (2.50e-1)" "unprognostic (8.48e-2)" "unprognostic (7.21e-4)" "unprognostic (7.01e-4)" "unprognostic (1.13e-1)" "unprognostic (6.41e-2)" 1.5 0.6 0.1 1.8 0.1 0.0 0.5 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.2 7.6 2081.3 0.1 6.7 0.1 0.8 0.3 0.3 0.0 0.1 0.1 0.4 0.2 0.2 0.2 0.1 0.0 0.2 0.1 0.7 0.2 0.1 6.1 0.2 0.1 0.2 0.0 0.1 0.2 0.0 0.4 0.2 0.1 0.0 0.0 0.1 0.1 1.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 2.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.1 0.9 0.3 0.0 0.6 0.0 0.3 0.0 0.0 0.3 0.8 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.5 0.3 0.1 0.1 0.0 2.4 0.0 0.4 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.8 0.4 0.1 0.2 0.1 0.5 3.2 0.0 0.0 2.2 0.4 0.1 0.0 0.0 1.2 0.0 0.1 1.8 11.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 18.7 0.0 0.0 0.0 9.9 0.0 0.0 0.0 6.0 15.0 320.0 5.6 0.0 0.4 0.0 0.0 16.9 0.4 0.2 1.2 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.2 0.0 41.0 2.1 0.3 1.5 0.0 0.0 0.3 1.4 5.6 0.1 0.1 CFL2 NEM7 ENSG00000165410 "Cofilin 2" Q9Y281 14 34709113-34714823 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 372.8;skeletal muscle: 719.9;tongue: 686.4" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 522.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037078, HPA045599" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 47000000 "Cluster 37: B-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB037078: AB_259128, HPA045599: AB_2679383" "unprognostic (1.05e-1)" "unprognostic (1.28e-1)" "unprognostic (1.29e-2)" "unprognostic (1.59e-1)" "unprognostic (3.02e-2)" "unprognostic (2.80e-3)" "unprognostic (3.82e-1)" "unprognostic (2.02e-1)" "unprognostic (3.02e-1)" "unprognostic (2.92e-2)" "unprognostic (2.48e-2)" "unprognostic (1.27e-1)" "unprognostic (1.65e-2)" "unprognostic (3.13e-3)" "unprognostic (9.59e-2)" "unprognostic (1.89e-2)" "prognostic unfavorable (2.16e-5)" 48.7 52.5 71.7 28.6 98.7 18.1 24.6 90.3 116.1 39.8 53.9 92.5 14.3 73.4 19.5 69.0 42.6 24.1 372.8 69.4 85.0 31.4 125.9 24.9 10.7 85.7 83.6 41.2 9.4 24.4 10.9 35.3 88.7 75.4 28.1 41.0 17.1 107.3 719.9 8.2 24.0 115.0 74.7 12.7 36.1 21.7 81.2 10.4 29.4 686.4 9.9 56.8 24.3 130.5 87.1 77.7 49.5 32.0 51.1 185.6 27.9 146.6 170.5 145.6 151.4 61.9 38.5 30.6 58.5 245.2 104.9 17.1 107.4 32.5 268.6 4.2 45.0 6.6 87.4 144.5 81.6 8.2 5.3 139.3 12.4 122.2 67.7 96.8 145.9 4.5 9.9 26.8 186.9 25.5 6.3 4.3 16.3 15.4 118.9 5.4 158.1 4.7 55.1 17.7 10.3 41.7 96.6 21.5 51.2 36.2 47.8 7.5 124.6 140.9 93.0 66.1 72.9 34.3 22.8 11.7 51.7 11.4 34.5 1.8 1.0 1.3 1.9 1.0 3.1 4.9 2.2 2.1 1.6 3.0 1.7 1.8 0.3 1.8 0.4 1.6 2.1 0.9 71.7 98.7 90.3 116.1 69.4 85.0 85.7 83.6 88.7 74.7 81.2 130.5 39.6 105.8 41.6 6.2 17.0 20.0 88.6 31.3 23.9 62.8 19.6 16.6 522.2 22.8 26.3 22.0 20.9 32.2 11.5 0.9 60.7 45.2 2.6 40.3 60.5 45.1 9.5 11.4 9.6 39.7 60.5 69.9 6.1 56.2 5.7 25.8 47.2 112.0 15.6 77.4 14.2 2.4 57.0 15.7 14.4 10.1 57.2 10.6 30.2 11.2 5.7 112.9 15.5 8.0 93.8 24.7 4.0 98.6 60.4 84.0 1.0 101.9 24.7 57.8 32.9 83.9 115.8 49.3 51.9 16.1 19.5 21.3 21.1 47.9 4.6 58.5 CHP1 "CHP, p22, p24, Sid470p, SLC9A1BP" ENSG00000187446 "Calcineurin like EF-hand protein 1" Q99653 15 41230839-41281887 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Protein kinase inhibitor" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 434.4;Distal tubular cells: 389.4;Hepatocytes: 353.6;Proximal enterocytes: 425.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006616 Approved Approved Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA006616: AB_1857461" "unprognostic (2.06e-2)" "unprognostic (3.26e-1)" "unprognostic (2.84e-1)" "prognostic favorable (9.63e-4)" "unprognostic (7.29e-2)" "unprognostic (3.74e-1)" "prognostic favorable (4.07e-6)" "unprognostic (2.20e-1)" "unprognostic (7.46e-2)" "unprognostic (3.26e-2)" "unprognostic (1.26e-3)" "unprognostic (2.79e-1)" "prognostic favorable (2.79e-6)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" "unprognostic (4.62e-3)" "unprognostic (2.04e-1)" 66.9 55.3 22.1 28.0 24.4 58.4 32.8 26.0 26.5 34.0 24.7 113.8 85.4 21.8 34.1 74.5 20.8 48.1 53.2 30.3 32.9 76.1 185.1 52.7 18.6 32.9 31.0 19.1 42.2 54.1 21.6 26.3 35.8 34.3 81.9 20.5 49.9 27.5 81.0 45.5 70.0 27.6 26.9 20.2 112.7 10.7 33.3 20.1 49.8 86.5 41.1 44.8 41.3 28.4 72.4 72.7 28.3 109.0 120.4 113.8 41.0 56.2 69.1 44.8 48.0 66.6 140.4 12.6 59.8 77.7 47.7 89.0 56.0 83.9 51.5 44.8 20.0 50.8 58.1 103.6 93.5 66.5 73.7 116.7 98.8 51.9 53.3 68.0 82.1 37.9 81.2 79.5 52.5 43.5 27.7 72.5 29.0 118.4 35.9 35.9 46.2 34.0 92.5 144.1 17.4 44.3 96.4 178.2 48.7 49.9 101.0 66.3 108.3 47.5 50.3 76.9 36.7 45.0 131.6 59.4 84.9 42.2 44.1 255.5 227.6 274.8 49.5 204.4 51.5 40.2 46.2 50.0 152.1 33.0 29.1 41.4 173.3 56.5 207.4 95.1 60.7 116.5 22.1 24.4 26.0 26.5 30.3 32.9 32.9 31.0 35.8 26.9 33.3 28.4 28.3 44.8 117.3 20.9 26.8 72.3 62.4 48.1 20.5 11.0 101.6 39.2 80.5 243.1 50.7 103.0 10.4 33.3 38.3 434.4 389.4 96.7 52.5 68.0 48.8 39.5 55.6 58.5 24.8 150.6 62.4 38.2 112.7 114.4 37.4 18.9 78.1 353.6 68.5 11.8 21.0 136.2 34.6 170.1 134.8 122.6 29.5 77.1 129.9 19.7 113.4 32.7 36.0 9.5 23.6 173.9 206.4 29.3 24.0 80.1 425.0 231.1 33.7 10.3 26.3 46.6 41.4 13.7 19.3 50.6 108.5 66.9 32.9 65.7 161.4 130.8 CHPT1 CPT1 ENSG00000111666 "Choline phosphotransferase 1" Q8WUD6 12 101696947-101744140 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 344.4;Late spermatids: 650.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 36.9;eosinophil: 14.6" "Lineage enriched" "Detected in all" 8 "granulocytes: 36.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067643 Approved Supported Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "HPA067643: " "unprognostic (1.59e-3)" "unprognostic (1.02e-1)" "unprognostic (1.91e-1)" "unprognostic (9.48e-2)" "unprognostic (3.15e-1)" "unprognostic (9.17e-2)" "unprognostic (5.79e-2)" "unprognostic (4.83e-2)" "unprognostic (1.12e-1)" "unprognostic (4.70e-1)" "unprognostic (5.27e-2)" "unprognostic (1.16e-2)" "unprognostic (1.52e-2)" "unprognostic (3.35e-1)" "unprognostic (1.72e-1)" "prognostic favorable (7.41e-4)" "unprognostic (1.79e-1)" 39.8 47.7 48.6 17.7 49.1 62.0 102.9 43.8 65.6 50.5 41.9 49.4 88.1 19.2 56.1 24.9 33.4 40.2 91.3 46.1 47.3 73.5 157.4 38.4 20.0 50.0 51.2 18.7 25.0 92.4 12.4 22.8 44.9 35.0 48.9 4.8 130.0 50.0 27.8 28.0 75.7 18.8 50.0 23.5 56.0 28.1 54.4 9.0 38.0 28.3 21.2 32.4 26.2 48.9 11.3 51.2 13.7 29.3 106.6 35.7 38.9 40.2 46.2 39.7 25.5 19.3 7.7 17.3 22.1 55.1 54.3 16.9 83.8 14.2 37.3 26.2 70.1 69.7 25.7 112.6 59.4 34.8 13.5 33.6 4.1 18.0 32.7 59.0 20.0 36.4 102.8 43.1 39.4 27.6 20.8 118.5 36.2 53.8 67.4 15.9 26.8 12.4 17.9 43.4 13.8 10.4 37.2 52.3 103.2 21.4 53.8 23.6 14.7 36.1 18.7 28.5 39.9 24.3 7.9 21.2 28.4 39.7 53.4 36.9 2.2 14.6 0.6 1.7 0.6 4.4 1.2 0.9 2.9 2.6 0.4 0.6 3.1 4.6 2.2 3.7 0.6 0.5 48.6 49.1 43.8 65.6 46.1 47.3 50.0 51.2 44.9 50.0 54.4 48.9 27.1 48.1 27.6 159.6 135.1 37.5 313.3 4.2 21.6 19.3 243.8 76.7 45.3 102.9 13.1 64.4 29.2 123.9 32.6 61.7 70.5 8.1 344.4 17.1 50.2 22.5 21.1 168.6 95.8 13.8 56.1 75.4 69.8 21.0 10.8 15.3 31.1 189.7 56.4 35.3 95.6 53.4 2.0 102.9 55.7 650.9 85.4 81.2 145.9 36.5 27.0 68.1 5.2 65.9 10.2 9.6 113.3 89.1 55.4 172.1 174.1 183.7 4.3 16.0 19.7 88.2 37.8 193.8 43.2 43.1 43.2 60.3 41.3 3.4 90.7 291.6 CHRDL1 "CHL, MGC1, NRLN1" ENSG00000101938 "Chordin like 1" Q9BU40 X 110673856-110795819 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Differentiation, Neurogenesis, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 224.4" "Group enriched" "Detected in many" 4 "Astrocytes: 50.3;Fibroblasts: 83.8;Leydig cells: 41.0;Muller glia cells: 81.6" "Cancer enhanced" "Detected in many" "prostate cancer: 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "ASC diff: 537.8;ASC TERT1: 724.7;hTERT-RPE1: 341.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000226, HPA000250" Approved "Secreted in other tissues" NA NA 610000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA000226: AB_1078522, HPA000250: AB_1078521" "unprognostic (5.13e-2)" "unprognostic (6.31e-2)" "unprognostic (8.50e-3)" "unprognostic (2.48e-3)" "unprognostic (1.99e-2)" "unprognostic (1.72e-2)" "unprognostic (7.26e-3)" "unprognostic (1.42e-2)" "unprognostic (4.89e-2)" "unprognostic (5.54e-2)" "unprognostic (3.43e-2)" "unprognostic (3.56e-1)" "prognostic unfavorable (2.36e-4)" "unprognostic (4.75e-3)" "unprognostic (7.91e-2)" "unprognostic (5.01e-2)" "prognostic unfavorable (2.23e-4)" 188.3 7.3 7.1 26.2 14.5 0.9 69.8 8.3 14.1 38.8 6.5 74.8 10.8 148.2 20.2 58.0 53.5 47.9 22.0 9.4 6.2 15.1 1.8 76.3 24.4 4.4 4.5 7.1 12.5 84.9 6.4 21.9 4.0 141.6 35.5 55.6 23.3 224.4 6.1 17.5 22.1 101.3 4.3 16.0 17.9 6.5 5.8 10.9 37.8 34.9 11.7 28.3 20.0 6.3 0.0 0.1 3.3 0.0 537.8 724.7 0.3 7.6 3.3 18.8 16.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 23.0 0.0 17.6 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 58.7 0.1 1.6 0.0 341.2 0.0 2.0 0.0 0.0 0.1 0.0 1.0 0.3 21.3 0.0 0.0 0.0 0.0 0.1 3.0 0.0 1.7 5.2 0.0 0.0 0.4 1.4 0.0 0.0 0.0 5.8 4.2 60.4 7.8 0.1 0.1 0.0 5.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 7.1 14.5 8.3 14.1 9.4 6.2 4.4 4.5 4.0 4.3 5.8 6.3 8.4 0.0 2.7 50.3 0.1 4.8 0.0 0.0 0.6 1.5 0.3 0.4 2.3 0.0 1.8 1.8 0.0 0.1 0.1 0.0 0.0 0.3 0.3 0.0 1.0 13.8 0.0 0.0 4.2 0.0 0.1 83.8 2.0 0.2 1.3 0.3 2.2 0.1 0.2 0.0 9.3 0.0 0.0 0.0 8.1 1.4 41.0 1.1 8.8 1.0 0.0 81.6 0.0 13.6 0.2 0.0 0.0 9.1 1.4 0.3 0.0 4.1 1.5 2.9 0.0 2.7 11.2 0.2 8.2 0.3 4.4 0.1 1.0 0.0 0.0 0.1 CHST4 "HEC-GLCNAC-6-ST, LSST" ENSG00000140835 "Carbohydrate sulfotransferase 4" Q8NCG5 16 71525233-71538748 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Inflammatory response" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "gallbladder: 69.4" "Cell type enriched" "Detected in some" 24 "Cholangiocytes: 165.8" "Cancer enriched" "Detected in many" 6 "pancreatic cancer: 10.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 8.6;HL-60: 2.7;NB-4: 5.0;NTERA-2: 7.5;SCLC-21H: 3.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA021955 Enhanced "Intracellular and membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 5: NTERA-2 - Transcription" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA021955: AB_1846723" "unprognostic (2.22e-3)" "unprognostic (1.41e-1)" "unprognostic (8.87e-2)" "unprognostic (3.35e-2)" "unprognostic (4.76e-3)" "unprognostic (6.86e-2)" "prognostic unfavorable (9.24e-4)" "unprognostic (1.26e-1)" "unprognostic (1.70e-1)" "unprognostic (1.15e-2)" "unprognostic (1.00e-1)" "unprognostic (2.27e-6)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (5.46e-2)" "unprognostic (1.73e-1)" 0.4 1.3 0.0 0.2 0.1 0.0 0.2 0.0 0.0 2.5 1.7 0.0 0.0 0.1 0.0 0.2 5.4 69.4 0.0 0.2 0.1 0.0 4.4 0.2 1.3 0.4 0.6 0.0 12.4 0.0 0.5 0.0 0.4 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.1 0.2 0.0 0.0 1.9 0.0 0.0 0.1 1.3 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.3 0.1 0.0 0.3 0.1 0.0 0.6 0.1 0.0 0.2 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 7.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 2.1 0.1 1.5 0.0 0.0 1.6 0.0 0.1 0.1 0.0 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.4 0.6 0.4 0.3 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 1.3 0.0 0.0 0.0 0.0 0.1 165.8 6.7 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 3.7 0.4 0.0 0.0 0.0 0.4 0.7 0.0 0.3 0.0 3.8 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 CHTF8 "CTF8, FLJ20400" ENSG00000168802 "Chromosome transmission fidelity factor 8" P0CG13 16 69118010-69132588 "Predicted intracellular proteins" "Cell cycle, DNA replication" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 7: Non-specific - Mitochondria" "unprognostic (7.86e-3)" "unprognostic (1.99e-2)" "unprognostic (2.59e-2)" "unprognostic (2.46e-2)" "unprognostic (6.44e-2)" "unprognostic (1.75e-2)" "unprognostic (1.73e-2)" "unprognostic (9.86e-3)" "unprognostic (9.88e-2)" "unprognostic (7.45e-2)" "unprognostic (2.96e-1)" "unprognostic (1.02e-1)" "prognostic favorable (3.59e-9)" "unprognostic (3.74e-2)" "unprognostic (1.85e-1)" "unprognostic (3.75e-2)" "unprognostic (1.45e-1)" 30.5 38.8 27.0 20.0 29.8 12.3 30.7 26.2 45.0 30.9 33.4 32.5 23.6 33.5 39.6 39.5 41.6 17.3 33.5 29.0 27.7 57.0 62.5 31.4 31.2 26.9 27.1 26.6 42.2 43.6 29.9 24.9 26.9 36.6 32.8 17.8 36.1 30.6 27.7 35.0 32.0 35.4 27.2 41.9 42.1 37.0 27.4 36.5 36.6 23.2 42.5 34.8 26.3 29.4 69.1 58.3 48.8 20.1 66.2 57.5 53.0 55.2 49.7 64.3 62.7 45.3 70.4 64.1 64.3 48.5 38.7 83.7 41.3 92.9 64.0 46.2 46.7 58.2 40.6 34.7 49.1 76.1 60.1 55.5 54.4 63.1 48.1 54.0 85.9 46.5 59.9 26.2 65.8 65.4 55.7 58.7 25.3 82.6 49.8 68.6 36.7 78.5 75.2 50.6 51.4 33.7 83.0 29.7 55.2 46.6 50.7 41.5 67.7 36.0 44.5 25.4 40.6 57.9 63.8 64.8 34.3 36.2 28.6 77.2 41.9 39.1 32.7 42.1 35.4 37.4 33.5 39.7 39.1 41.5 33.5 33.3 23.5 33.5 45.6 33.8 40.6 46.5 27.0 29.8 26.2 45.0 29.0 27.7 26.9 27.1 26.9 27.2 27.4 29.4 22.9 16.0 14.2 7.2 31.2 14.4 21.1 26.5 32.5 12.3 32.4 30.6 12.8 24.3 15.5 23.9 4.2 66.6 21.4 32.7 60.7 40.6 7.4 21.1 16.9 27.1 28.2 25.2 5.3 48.2 63.6 21.8 15.8 17.5 7.0 28.4 26.7 36.8 43.4 6.7 5.8 27.7 12.2 30.4 19.7 18.5 21.5 24.8 12.4 9.4 40.2 21.7 25.7 9.0 11.1 44.8 22.2 27.1 27.2 29.2 27.7 75.6 18.0 10.4 6.6 17.6 21.7 26.4 49.1 19.5 17.2 66.6 22.7 29.1 32.4 21.4 CIB2 "DFNB48, KIP2, USH1J" ENSG00000136425 "Calcium and integrin binding family member 2" O75838 15 78104606-78131535 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 47.7;lymphoid tissue: 47.8" "Group enriched" "Detected in many" 4 "Early spermatids: 73.1;Late spermatids: 269.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 48 "plasmacytoid DC: 18.7" "Lineage enriched" "Detected in single" 48 "dendritic cells: 18.7" "Cell line enhanced" "Detected in many" "AN3-CA: 44.0;GAMG: 39.0;HAP1: 38.6;SCLC-21H: 38.8;SH-SY5Y: 40.1;SuSa: 49.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036697 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "HPA036697: AB_10672475" "unprognostic (5.77e-2)" "unprognostic (1.83e-2)" "unprognostic (2.81e-2)" "prognostic unfavorable (7.05e-4)" "unprognostic (1.46e-1)" "unprognostic (2.57e-1)" "unprognostic (1.11e-2)" "unprognostic (6.73e-3)" "unprognostic (1.66e-1)" "unprognostic (9.94e-3)" "unprognostic (3.18e-1)" "unprognostic (7.49e-2)" "prognostic favorable (6.16e-4)" "unprognostic (9.78e-2)" "unprognostic (1.01e-1)" "unprognostic (1.68e-1)" "unprognostic (7.64e-3)" 7.0 12.1 16.7 3.1 16.9 1.6 4.8 15.9 22.9 13.1 13.8 9.6 18.7 9.1 3.1 4.0 5.7 2.8 47.7 18.1 17.4 9.1 1.2 3.0 3.5 20.1 18.3 7.3 5.9 13.4 10.4 3.7 20.1 10.4 7.1 5.0 8.1 8.7 11.4 6.8 24.6 6.6 17.5 3.0 3.9 23.3 16.9 47.8 4.0 1.9 6.5 8.6 7.8 16.2 3.5 8.6 24.2 44.0 1.1 1.4 18.1 2.4 0.9 2.0 4.2 0.0 9.6 0.4 4.8 11.3 39.0 1.9 38.6 7.7 0.6 21.7 26.8 2.6 1.6 1.4 4.3 0.0 3.4 2.1 3.2 3.5 2.0 5.0 4.2 13.0 9.1 0.2 3.7 0.7 1.1 0.4 31.1 1.2 0.3 16.9 0.1 1.0 2.8 0.7 38.8 40.1 5.9 3.1 3.5 49.2 0.6 2.6 0.3 0.1 20.3 2.2 0.3 0.4 0.4 6.7 1.0 0.1 5.4 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.0 18.7 0.0 0.2 16.7 16.9 15.9 22.9 18.1 17.4 20.1 18.3 20.1 17.5 16.9 16.2 11.0 0.0 0.0 1.6 3.6 5.5 26.6 2.3 1.8 2.9 3.4 12.6 11.4 1.5 0.5 1.8 6.2 19.4 17.3 14.9 9.8 3.0 73.1 1.6 8.1 3.0 3.0 3.0 1.6 1.1 15.5 9.5 2.0 1.5 0.0 10.7 2.5 0.4 2.8 5.0 3.9 25.1 2.0 0.6 1.4 269.9 3.4 2.3 7.2 1.0 0.1 18.1 1.0 2.5 0.4 1.5 16.2 2.6 1.7 12.3 35.9 10.6 0.2 2.2 6.6 11.5 4.9 10.0 17.5 0.4 3.1 9.3 2.5 18.0 11.1 11.5 CILK1 "ICK, KIAA0936, LCK2, MGC46090, MRK" ENSG00000112144 "Ciliogenesis associated kinase 1" Q9UPZ9 6 53001279-53061824 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 11.0;Cytotrophoblasts: 20.6;Extravillous trophoblasts: 33.9;Syncytiotrophoblasts: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000791, HPA001113" Approved Supported "Nucleoli fibrillar center" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 24: Non-specific - Transcription regulation" "Nucleoli fibrillar center" "HPA000791: AB_2732392, HPA001113: AB_1851385" "unprognostic (1.75e-2)" "unprognostic (1.02e-1)" "unprognostic (5.47e-2)" "unprognostic (2.95e-1)" "unprognostic (2.32e-1)" "unprognostic (1.00e-2)" "unprognostic (1.44e-1)" "unprognostic (1.82e-2)" "unprognostic (1.17e-3)" "unprognostic (5.11e-2)" "unprognostic (1.18e-1)" "unprognostic (8.28e-2)" "unprognostic (8.12e-3)" "unprognostic (1.21e-1)" "unprognostic (1.39e-1)" "unprognostic (1.07e-1)" "unprognostic (2.26e-1)" 7.9 17.9 10.2 4.9 11.0 2.7 10.7 8.4 9.7 8.9 5.1 8.7 9.8 8.0 5.5 8.6 7.4 6.9 8.5 6.8 7.8 4.5 7.5 6.3 5.2 9.4 11.6 9.5 5.0 7.3 1.7 12.1 8.8 9.9 10.7 17.4 17.9 7.3 4.0 8.7 10.4 7.4 8.8 5.6 12.9 4.5 14.9 10.1 6.3 5.0 6.2 6.5 5.8 12.8 7.8 2.9 14.6 10.0 8.9 14.0 17.0 6.9 12.4 10.8 12.3 4.1 2.4 5.7 4.0 21.0 3.5 5.0 17.6 7.1 14.2 19.9 7.0 4.2 3.3 22.3 4.5 5.2 5.4 12.5 7.6 4.6 5.3 7.7 10.2 12.1 8.1 22.6 24.9 6.7 5.6 6.4 5.6 27.0 6.3 8.8 6.5 7.5 4.5 5.6 23.6 10.6 6.7 16.3 9.6 14.2 9.5 10.9 8.5 17.2 8.0 6.5 17.1 6.3 4.8 2.2 3.5 5.0 8.5 2.8 1.0 2.2 1.7 0.8 1.5 1.2 1.2 1.4 1.0 1.5 1.4 1.2 0.5 1.1 0.9 1.4 1.7 0.8 10.2 11.0 8.4 9.7 6.8 7.8 9.4 11.6 8.8 8.8 14.9 12.8 6.3 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 20.6 5.7 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 33.9 5.3 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 58.1 0.8 0.0 0.0 0.0 CLDN10 "CPETRL3, OSP-L" ENSG00000134873 "Claudin 10" P78369 13 95433604-95579759 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 135.2;pancreas: 216.5;salivary gland: 91.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 182.4;Cholangiocytes: 328.8;Club cells: 251.6;Ductal cells: 394.1;Glandular and luminal cells: 220.2;Proximal tubular cells: 285.9" "Cancer enhanced" "Detected in many" "pancreatic cancer: 19.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "eosinophil: 1.3;neutrophil: 4.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 4.1" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 14.9;NTERA-2: 12.7;RPTEC TERT1: 29.0;SuSa: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012969, HPA042348" Enhanced NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB012969: AB_2533386, HPA042348: AB_2677955" "unprognostic (6.45e-2)" "unprognostic (5.72e-2)" "unprognostic (3.35e-1)" "unprognostic (4.60e-2)" "unprognostic (4.73e-2)" "unprognostic (2.46e-3)" "unprognostic (6.91e-2)" "unprognostic (2.60e-1)" "unprognostic (1.88e-1)" "unprognostic (1.91e-3)" "unprognostic (2.59e-3)" "unprognostic (7.93e-2)" "prognostic favorable (7.46e-5)" "unprognostic (1.11e-2)" "unprognostic (9.94e-2)" "prognostic favorable (2.13e-4)" "unprognostic (4.75e-3)" 1.0 0.1 33.0 0.0 31.3 3.2 3.1 28.6 45.8 30.4 24.1 0.3 1.1 9.3 20.8 7.9 19.2 25.5 0.5 32.6 30.5 135.2 3.7 2.1 0.0 27.9 30.2 0.9 216.5 0.4 3.1 0.8 27.2 1.3 0.4 2.7 91.5 0.4 0.1 16.8 0.2 0.4 27.4 0.7 0.9 1.5 30.1 0.5 0.2 0.7 27.4 0.5 0.4 29.8 0.0 0.0 0.9 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 2.7 0.0 4.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.3 1.9 0.0 0.0 2.9 0.0 0.1 0.0 0.5 14.9 0.0 0.0 0.0 0.0 0.1 0.0 0.2 12.7 0.2 0.0 0.0 0.1 0.0 29.0 0.0 0.2 0.1 0.0 0.0 0.0 73.3 0.7 1.8 0.6 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.1 0.0 0.0 33.0 31.3 28.6 45.8 32.6 30.5 27.9 30.2 27.2 27.4 30.1 29.8 0.6 0.0 0.0 93.4 1.0 0.3 5.5 182.4 0.0 0.3 22.6 5.0 0.8 328.8 251.6 99.3 0.0 15.0 0.4 0.0 135.0 394.1 3.4 83.2 28.5 4.2 0.0 0.0 0.6 82.5 7.9 1.4 0.0 220.2 0.0 0.1 1.1 0.4 1.9 0.0 1.6 0.0 77.3 0.3 0.3 2.5 0.0 2.8 69.4 4.7 1.6 78.7 0.0 33.7 0.4 103.1 0.0 0.4 0.1 22.1 0.0 285.9 43.3 3.8 6.6 0.2 16.8 12.2 19.9 1.5 0.6 23.1 2.2 0.5 0.0 5.0 CLDN16 "HOMG3, PCLN1" ENSG00000113946 "Claudin 16" Q9Y5I7 3 190322541-190412138 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Disease variant, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "kidney: 63.6" "Cell type enriched" "Detected in some" 8 "Distal tubular cells: 187.9" "Group enriched" "Detected in many" 15 "ovarian cancer: 39.8;thyroid cancer: 29.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 153 "EFO-21: 691.6;RPTEC TERT1: 233.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA056020 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA056020: AB_2683011" "unprognostic (5.01e-2)" "unprognostic (7.83e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.99e-5)" "unprognostic (6.06e-4)" "unprognostic (1.30e-1)" "unprognostic (2.07e-1)" "unprognostic (2.39e-2)" "unprognostic (3.31e-1)" "unprognostic (4.20e-1)" "unprognostic (2.76e-3)" "unprognostic (3.70e-1)" "unprognostic (1.96e-1)" "unprognostic (5.76e-2)" "unprognostic (8.08e-2)" "unprognostic (1.62e-2)" "unprognostic (1.15e-1)" 0.1 0.7 0.3 0.2 0.4 0.0 0.2 0.0 0.5 0.1 1.5 0.0 0.0 0.3 0.6 0.5 2.9 0.7 0.0 0.2 0.2 63.6 2.2 0.4 1.5 0.2 0.1 0.0 0.2 0.0 0.0 0.2 0.2 0.1 0.0 0.1 0.4 0.9 0.0 3.2 0.0 0.4 0.1 0.1 0.1 0.1 0.3 0.3 9.7 0.0 1.0 0.3 0.2 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 691.6 0.0 0.3 0.7 0.0 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.8 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 233.2 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.3 0.0 0.0 2.2 0.0 0.3 1.4 1.2 3.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.5 0.2 0.2 0.2 0.1 0.2 0.1 0.3 0.6 0.1 0.0 0.0 0.3 0.0 7.0 5.8 2.6 0.6 0.3 0.8 0.3 0.4 4.3 1.6 9.2 0.0 0.4 0.0 0.0 187.9 3.4 2.0 3.0 0.1 0.2 0.0 0.0 5.0 0.4 0.2 0.9 0.0 0.5 1.3 0.3 0.0 1.6 0.1 3.3 3.6 0.0 0.0 0.3 1.2 0.2 0.0 0.4 5.4 2.8 0.0 0.2 0.0 4.0 0.1 0.5 0.0 0.4 0.0 6.7 0.0 0.9 22.1 0.2 0.0 0.8 0.6 0.3 0.3 0.9 12.6 6.2 0.2 0.2 0.0 3.1 CLDN5 "AWAL, BEC1, CPETRL1, TMVCF" ENSG00000184113 "Claudin 5" O00501 22 19523024-19527545 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 439.7;breast: 420.9;lung: 398.7" "Group enriched" "Detected in many" 10 "Adipocytes: 2644.3;Endothelial cells: 775.2;Hepatic stellate cells: 701.4" "Cancer enriched" "Detected in all" 4 "glioma: 32.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 18.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 18.8" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 85.4;SCLC-21H: 53.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002607 Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002607: " "unprognostic (1.26e-1)" "unprognostic (2.05e-3)" "unprognostic (1.77e-2)" "unprognostic (2.07e-1)" "unprognostic (3.05e-3)" "unprognostic (6.00e-2)" "unprognostic (4.98e-2)" "unprognostic (3.24e-3)" "unprognostic (1.33e-1)" "unprognostic (8.95e-2)" "unprognostic (2.29e-3)" "unprognostic (1.15e-1)" "unprognostic (7.31e-2)" "unprognostic (2.01e-2)" "unprognostic (2.47e-2)" "unprognostic (2.22e-1)" "unprognostic (2.96e-2)" 439.7 16.2 124.1 6.1 101.0 0.3 420.9 111.7 127.4 70.2 205.2 75.9 9.2 86.1 3.0 54.4 83.1 6.5 138.3 93.8 103.3 45.5 16.9 398.7 9.6 124.5 114.0 36.4 20.7 1.5 16.9 12.5 127.8 50.2 3.6 2.0 36.0 3.5 101.6 95.9 71.0 6.4 109.2 44.8 41.4 10.5 160.7 1.8 122.5 14.9 2.2 103.7 75.9 107.4 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.3 0.1 0.1 0.2 1.1 0.0 0.0 0.0 0.0 85.4 0.1 0.7 0.2 0.1 0.0 0.1 0.5 0.2 0.0 0.2 0.9 0.7 0.1 0.0 0.0 53.0 0.3 0.0 0.0 0.0 0.0 0.4 0.2 7.1 0.1 1.1 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.2 18.8 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.3 0.2 4.6 0.2 5.8 0.0 0.1 0.1 0.0 26.9 124.1 101.0 111.7 127.4 93.8 103.3 124.5 114.0 127.8 109.2 160.7 107.4 2644.3 3.2 7.7 0.7 2.4 32.4 1.1 0.1 3.4 1.8 5.9 7.6 14.8 2.8 0.6 7.3 0.0 0.3 4.2 0.0 0.0 0.7 5.0 8.1 0.7 775.2 2.4 8.0 0.0 0.8 0.1 12.5 0.0 1.0 1.3 0.3 701.4 2.7 0.8 0.0 0.1 0.2 4.1 17.0 33.3 5.5 5.3 46.2 14.2 129.3 0.7 2.4 1.0 0.5 0.3 0.0 0.0 0.7 2.8 4.0 0.0 0.0 0.3 7.3 0.0 61.7 12.1 1.1 1.9 1.2 30.5 0.0 4.6 25.0 0.0 6.7 CLEC14A C14orf27 ENSG00000176435 "C-type lectin domain containing 14A" Q86T13 14 38254000-38256093 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 13 "Adipocytes: 396.6;Endothelial cells: 272.8;Hepatic stellate cells: 567.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 83.7;HUVEC TERT2: 451.8;TIME: 158.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039468, HPA048119" Uncertain Supported "Endoplasmic reticulum,Golgi apparatus" NA NA 4100000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum, Golgi apparatus" "HPA039468: AB_2676524, HPA048119: AB_2680270" "unprognostic (4.02e-1)" "unprognostic (4.26e-2)" "unprognostic (4.20e-3)" "unprognostic (9.44e-2)" "unprognostic (1.35e-1)" "prognostic favorable (4.13e-6)" "unprognostic (2.55e-3)" "unprognostic (2.69e-1)" "unprognostic (1.67e-1)" "unprognostic (6.90e-2)" "unprognostic (5.41e-2)" "unprognostic (1.26e-1)" "unprognostic (1.63e-2)" "unprognostic (1.75e-2)" "unprognostic (1.55e-1)" "unprognostic (4.97e-2)" "unprognostic (5.28e-2)" 67.1 9.5 13.6 7.9 13.4 0.1 50.6 13.8 15.2 24.8 10.9 15.2 10.1 31.2 7.6 11.1 22.6 19.0 65.1 11.5 13.3 15.9 9.4 55.5 6.6 15.0 13.9 9.5 7.8 10.5 6.1 25.0 15.4 14.5 7.2 0.8 13.6 9.8 33.2 15.8 18.8 19.8 13.1 16.7 13.8 3.5 14.9 4.6 31.4 43.3 4.2 19.2 16.8 15.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 451.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 158.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 13.4 13.8 15.2 11.5 13.3 15.0 13.9 15.4 13.1 14.9 15.6 396.6 0.0 3.2 0.0 0.9 3.4 0.2 0.0 1.8 0.1 1.5 2.5 6.4 1.5 0.6 0.0 0.0 0.1 0.2 0.0 0.0 0.1 1.1 0.2 0.5 272.8 0.0 0.0 0.4 0.2 0.1 31.0 0.0 0.3 1.3 0.1 567.2 2.1 0.4 0.0 0.2 0.0 0.0 6.4 3.1 1.0 0.6 1.1 5.4 15.0 0.0 0.2 0.0 4.0 2.9 0.0 0.0 0.4 1.4 0.2 0.0 0.0 0.0 0.5 0.0 14.1 7.5 1.6 0.9 0.9 3.1 0.1 1.3 6.7 0.0 0.3 CLEC2D "CLAX, LLT1, OCIL" ENSG00000069493 "C-type lectin domain family 2 member D" Q9UHP7 12 9664969-9699553 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 53.5" "Cell type enhanced" "Detected in many" "B-cells: 128.6;dendritic cells: 112.0;Early spermatids: 95.5;monocytes: 81.6;NK-cells: 131.8;T-cells: 215.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 10 "gdT-cell: 188.1;MAIT T-cell: 114.5;memory B-cell: 95.0;memory CD4 T-cell: 183.3;memory CD8 T-cell: 208.7;naive B-cell: 127.5;naive CD4 T-cell: 192.3;naive CD8 T-cell: 223.0;T-reg: 175.2" "Group enriched" "Detected in all" 11 "B-cells: 127.5;T-cells: 223.0" "Group enriched" "Detected in many" 4 "Daudi: 67.9;HDLM-2: 53.3;Karpas-707: 31.0;U-698: 105.8" "HPA017649, HPA047584" Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus" "HPA017649: AB_1846912, HPA047584: " "unprognostic (1.09e-3)" "prognostic favorable (1.37e-4)" "unprognostic (1.16e-1)" "unprognostic (4.27e-2)" "unprognostic (1.29e-1)" "unprognostic (2.77e-4)" "unprognostic (4.34e-2)" "unprognostic (1.72e-3)" "unprognostic (1.24e-2)" "unprognostic (1.92e-1)" "unprognostic (6.87e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (5.85e-11)" "unprognostic (1.17e-1)" "unprognostic (2.70e-1)" "unprognostic (3.44e-1)" "prognostic favorable (1.68e-7)" 6.1 1.8 3.6 16.7 3.5 16.0 5.6 3.3 4.9 6.4 3.1 4.8 3.3 4.5 11.8 3.2 5.3 5.5 5.3 3.2 3.7 3.9 2.9 8.6 53.5 4.0 3.4 6.0 2.4 0.8 2.3 2.6 3.9 7.3 3.9 2.2 6.5 4.5 2.9 3.7 20.3 2.0 3.5 26.6 5.5 9.5 4.1 31.6 4.5 1.3 41.7 5.7 4.6 4.2 1.2 2.5 3.5 0.3 0.5 1.4 4.0 1.7 2.5 0.6 2.1 1.9 2.1 67.9 0.3 1.8 1.0 0.7 1.2 0.2 1.1 53.3 0.9 2.1 1.6 2.9 5.7 1.7 1.7 2.3 1.7 0.5 2.1 8.0 0.1 1.2 0.5 31.0 1.5 4.5 0.7 5.9 3.2 0.2 0.4 14.9 1.6 2.2 3.4 3.6 0.6 1.3 0.9 2.8 3.0 6.6 0.6 1.8 0.6 1.3 1.8 1.0 1.2 4.4 1.1 105.8 2.8 3.1 2.1 6.8 2.1 1.5 188.1 1.4 114.5 95.0 183.3 208.7 2.3 127.5 192.3 223.0 6.0 16.5 1.3 1.6 175.2 109.8 3.6 3.5 3.3 4.9 3.2 3.7 4.0 3.4 3.9 3.5 4.1 4.2 8.9 6.4 20.7 11.8 128.6 4.1 39.7 2.1 1.8 1.3 6.5 6.1 9.6 4.3 7.1 1.8 4.2 10.4 112.0 0.8 7.9 3.0 95.5 3.6 6.9 13.0 0.0 21.5 6.3 1.9 6.0 12.2 4.6 6.2 20.2 18.1 12.5 2.3 9.2 5.0 6.8 2.5 0.0 20.9 17.8 28.3 8.4 19.4 1.8 56.2 81.6 3.2 131.8 27.6 4.4 2.8 2.0 9.8 71.5 17.2 0.5 2.1 7.4 2.3 19.7 26.2 8.7 5.7 6.3 1.9 4.8 4.8 215.1 7.4 3.5 24.3 CLEC3B "TN, TNA" ENSG00000163815 "C-type lectin domain family 3 member B" P05452 3 45001548-45036071 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 420.3" "Cell type enhanced" "Detected in some" "Adipocytes: 76.3;Endothelial cells: 27.9;Fibroblasts: 126.4;Hepatic stellate cells: 57.5;Leydig cells: 30.1;Microglial cells: 69.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 297.9;ASC TERT1: 591.9;U-2197: 120.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002582, HPA034794" Approved "Secreted to blood" NA NA 6540000000 25000000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB002582: AB_564027, HPA034794: AB_2674332" "unprognostic (2.04e-1)" "unprognostic (1.80e-3)" "unprognostic (2.58e-1)" "unprognostic (4.57e-2)" "unprognostic (7.75e-2)" "prognostic favorable (1.53e-4)" "prognostic favorable (9.99e-9)" "unprognostic (1.75e-2)" "unprognostic (2.25e-1)" "unprognostic (4.02e-1)" "prognostic favorable (5.68e-4)" "unprognostic (9.33e-2)" "unprognostic (2.39e-2)" "unprognostic (7.46e-2)" "unprognostic (1.39e-1)" "unprognostic (5.54e-2)" "unprognostic (4.21e-2)" 420.3 51.0 44.4 9.3 46.4 1.7 214.8 45.5 66.6 89.4 50.9 83.9 31.6 60.4 17.1 49.9 41.1 35.6 259.9 43.0 42.9 131.4 29.0 201.2 33.1 51.3 56.1 26.0 14.6 14.3 27.7 142.8 48.0 33.5 37.4 0.7 49.8 19.1 74.8 149.7 78.2 25.5 44.8 264.5 43.5 113.2 50.7 10.1 88.4 68.0 8.2 100.9 74.9 43.0 0.0 0.0 0.1 0.2 297.9 591.9 0.0 40.1 62.9 1.2 6.2 0.0 0.0 0.1 0.1 3.1 0.0 0.1 0.0 0.1 0.1 0.3 0.9 0.6 0.1 0.1 0.5 0.1 0.7 47.5 0.1 0.3 0.1 0.4 0.5 0.3 0.0 1.7 0.5 0.2 0.0 2.2 0.0 0.0 0.6 0.0 0.1 2.2 0.0 0.0 0.3 1.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 4.5 0.2 120.6 0.1 1.0 1.2 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.4 46.4 45.5 66.6 43.0 42.9 51.3 56.1 48.0 44.8 50.7 43.0 76.3 0.0 0.0 1.6 0.3 3.4 0.0 0.0 1.8 0.0 0.7 0.3 0.8 1.5 0.0 0.0 0.0 0.0 0.5 0.0 3.9 0.0 4.0 0.3 16.9 27.9 0.0 2.7 0.8 0.2 0.0 126.4 3.1 0.3 0.0 0.0 57.5 0.3 0.9 0.0 0.6 0.0 0.0 1.2 9.5 19.5 30.1 2.2 3.6 69.3 0.7 0.4 0.0 1.5 0.7 0.1 0.0 6.4 0.5 0.0 0.0 0.0 0.0 0.3 0.0 1.0 12.3 0.0 0.0 0.7 3.8 0.1 0.7 0.4 0.0 0.0 CLEC4G "LSECtin, UNQ431" ENSG00000182566 "C-type lectin domain family 4 member G" Q6UXB4 19 7728958-7733906 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 14.9;liver: 53.3;lymphoid tissue: 15.1" "Cell type enriched" "Detected in some" 15 "Hepatic stellate cells: 730.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 18.8;myeloid DC: 15.1" "Group enriched" "Detected in many" 4 "dendritic cells: 15.1;monocytes: 18.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB003789, HPA014044" Enhanced NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB003789: , HPA014044: AB_1846916" "unprognostic (7.20e-2)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (3.64e-1)" "unprognostic (4.47e-2)" "unprognostic (1.35e-1)" "unprognostic (7.98e-2)" "unprognostic (1.64e-1)" "unprognostic (2.23e-1)" "unprognostic (3.29e-2)" "unprognostic (7.45e-2)" "unprognostic (3.04e-1)" "unprognostic (2.13e-8)" "unprognostic (5.21e-2)" "unprognostic (1.27e-1)" "unprognostic (1.77e-1)" "unprognostic (6.65e-2)" 14.9 0.5 1.9 2.4 1.9 1.2 2.6 4.0 2.9 0.1 2.0 1.4 0.4 0.1 0.3 0.4 4.8 1.6 1.2 2.5 1.9 0.5 53.3 1.0 15.1 2.3 2.1 0.5 0.3 0.0 0.1 1.0 2.1 0.3 0.9 0.0 1.1 0.3 0.4 1.1 2.0 1.0 2.1 3.4 0.9 0.4 4.3 0.2 0.5 0.0 0.3 7.7 0.4 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 18.8 0.0 0.0 4.2 0.0 0.3 0.0 0.0 15.1 4.2 0.1 0.0 0.4 0.5 0.5 0.7 0.0 4.5 1.9 1.9 4.0 2.9 2.5 1.9 2.3 2.1 2.1 2.1 4.3 2.1 0.1 0.0 0.0 0.3 3.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 7.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.0 0.0 18.7 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 730.3 7.1 0.8 0.0 1.1 0.0 0.0 46.7 2.9 0.0 0.3 2.6 0.0 0.0 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.7 0.0 0.3 0.3 1.1 0.8 0.0 0.1 CLNK MIST ENSG00000109684 "Cytokine dependent hematopoietic cell linker" Q7Z7G1 4 10486395-10684768 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 6.2" "Cell type enriched" "Detected in many" 5 "Ionocytes: 73.2" "Cancer enriched" "Detected in single" 13 "renal cancer: 3.3" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 6 "HDLM-2: 4.1;U-937: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035671, HPA035672" Uncertain Uncertain Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA035671: AB_10669673, HPA035672: AB_10669775" "unprognostic (2.47e-3)" "unprognostic (4.74e-4)" "unprognostic (1.99e-4)" "unprognostic (2.24e-3)" "unprognostic (1.17e-1)" "unprognostic (2.23e-6)" "unprognostic (2.05e-2)" "unprognostic (5.37e-4)" "unprognostic (9.87e-2)" "unprognostic (3.75e-2)" "unprognostic (2.55e-1)" "unprognostic (7.74e-3)" "unprognostic (1.55e-1)" "unprognostic (6.05e-3)" "unprognostic (6.65e-3)" "unprognostic (1.45e-1)" "unprognostic (2.99e-2)" 0.3 0.2 0.5 0.9 0.4 0.4 0.6 1.5 0.7 0.2 0.5 0.3 0.6 0.4 1.2 0.4 0.2 0.5 0.2 0.5 0.5 6.2 0.9 0.6 3.0 0.4 0.2 0.4 0.1 0.1 1.3 1.0 0.5 0.4 0.4 0.3 0.5 0.3 0.2 0.8 0.9 0.1 0.1 1.5 1.1 0.8 0.5 1.4 0.3 0.0 2.0 0.3 0.0 0.9 0.0 0.2 0.2 0.1 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 4.1 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.2 0.3 0.0 0.1 0.2 0.1 0.1 0.1 0.0 0.4 0.0 0.1 0.2 0.1 0.2 0.0 0.1 0.2 2.2 0.1 0.5 0.1 0.2 0.2 0.1 0.1 1.4 0.4 0.1 2.6 1.1 0.1 0.1 0.4 2.0 0.0 0.6 1.8 0.2 0.5 0.4 1.5 0.7 0.5 0.5 0.4 0.2 0.5 0.1 0.5 0.9 0.1 3.2 3.0 1.0 12.9 0.8 0.8 0.0 0.0 1.3 0.3 0.3 0.7 0.0 0.9 0.0 2.1 0.3 4.6 0.1 13.7 0.0 5.3 0.7 0.2 0.4 0.0 5.3 1.7 0.0 2.2 0.5 0.5 0.9 11.4 0.2 0.7 0.3 0.3 0.0 1.6 0.2 73.2 1.9 5.5 5.4 0.3 3.5 1.8 1.9 0.5 0.4 0.0 1.0 0.7 0.1 0.0 2.2 1.1 0.7 0.0 0.2 0.2 1.0 0.0 1.1 0.5 1.9 0.8 0.0 0.4 0.1 6.0 1.3 0.0 0.7 CLSTN2 "CDHR13, CS2, CSTN2, FLJ39113" ENSG00000158258 "Calsyntenin 2" Q9H4D0 3 139935185-140577397 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 18.2;brain: 26.7;ovary: 64.7" "Cell type enriched" "Detected in many" 4 "Excitatory neurons: 552.2" "Cancer enriched" "Detected in many" 7 "breast cancer: 15.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 32.7;SCLC-21H: 14.5;SuSa: 42.7;THP-1: 9.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031342, HPA061800" Approved Uncertain "Vesicles,Cytokinetic bridge" Yes No 130000 "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "Cytokinetic bridge" "HPA031342: AB_10602800, HPA061800: AB_2684615" "unprognostic (7.58e-2)" "unprognostic (2.64e-2)" "unprognostic (8.02e-2)" "unprognostic (1.51e-3)" "unprognostic (5.52e-3)" "unprognostic (8.35e-2)" "unprognostic (1.58e-1)" "unprognostic (1.21e-1)" "unprognostic (5.58e-1)" "unprognostic (6.25e-2)" "unprognostic (2.24e-1)" "unprognostic (1.81e-1)" "unprognostic (1.71e-1)" "unprognostic (2.52e-2)" "unprognostic (3.16e-2)" "unprognostic (7.63e-5)" "unprognostic (7.22e-5)" 18.2 4.8 17.3 0.3 15.3 0.0 8.8 0.0 26.7 4.2 0.0 1.4 0.5 5.1 0.7 1.0 4.7 2.1 6.1 23.4 0.0 4.3 0.8 1.1 2.7 13.3 3.1 64.7 1.6 0.8 0.9 0.9 9.1 5.3 0.8 2.7 1.3 1.1 1.6 2.0 1.3 6.8 0.0 0.1 1.0 0.6 0.0 0.7 2.8 2.2 0.2 1.6 3.2 15.6 0.0 0.0 5.1 0.0 2.2 0.6 0.0 0.7 0.0 0.0 0.0 2.9 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.1 2.5 0.0 0.1 0.0 32.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 2.1 0.0 0.0 0.0 42.7 2.2 9.4 0.0 1.0 0.5 1.4 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 15.3 0.0 26.7 23.4 0.0 13.3 3.1 9.1 0.0 0.0 15.6 2.1 0.0 0.0 18.3 0.0 0.5 0.3 0.0 8.6 1.8 10.9 2.2 8.0 0.0 0.6 3.7 0.0 0.2 0.1 0.0 1.9 0.2 39.8 0.5 8.9 0.8 0.0 0.0 552.2 0.2 0.0 9.1 0.0 0.2 0.0 25.0 2.2 0.0 0.1 0.0 111.5 0.0 0.0 0.3 1.5 31.1 28.0 0.8 0.0 5.6 0.0 0.8 0.0 108.6 29.4 0.0 0.0 0.7 0.0 5.0 0.0 32.3 3.0 3.8 0.0 28.3 13.7 0.8 0.8 0.4 0.0 0.0 0.7 0.5 0.0 0.3 CMKLR1 RVER1 ENSG00000174600 "Chemerin chemokine-like receptor 1" Q99788 12 108288044-108339317 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 34.3" "Cell type enhanced" "Detected in some" "dendritic cells: 17.3;Hofbauer cells: 32.4;Kupffer cells: 69.6;Macrophages: 27.1;Microglial cells: 39.4;NK-cells: 30.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 14.5;plasmacytoid DC: 18.1" "Group enriched" "Detected in many" 22 "dendritic cells: 18.1;monocytes: 14.5;T-cells: 7.0" "Cell line enhanced" "Detected in some" "ASC diff: 11.9;ASC TERT1: 45.3;BJ hTERT+: 34.9;hTERT-RPE1: 13.6;LHCN-M2: 10.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047865 Uncertain NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA047865: AB_2680191" "unprognostic (1.78e-1)" "unprognostic (2.61e-2)" "unprognostic (8.83e-3)" "unprognostic (7.39e-2)" "unprognostic (2.44e-1)" "unprognostic (3.49e-3)" "unprognostic (1.69e-1)" "unprognostic (2.94e-2)" "unprognostic (1.69e-1)" "unprognostic (6.83e-2)" "unprognostic (1.06e-1)" "unprognostic (8.72e-2)" "unprognostic (2.96e-2)" "unprognostic (1.77e-1)" "unprognostic (1.83e-2)" "unprognostic (5.19e-2)" "unprognostic (1.14e-1)" 10.4 5.9 3.3 11.7 3.0 0.9 4.9 2.5 3.2 4.7 4.2 7.5 4.5 8.3 1.6 3.1 4.4 5.5 6.4 2.6 4.9 3.3 6.9 12.8 17.6 5.9 4.7 1.9 3.2 1.7 3.4 22.2 5.3 3.8 8.9 0.3 4.7 4.5 2.4 4.2 5.1 14.7 4.0 34.3 2.8 2.6 5.9 4.2 8.7 5.1 8.1 8.1 2.5 7.5 0.0 0.0 0.1 0.0 11.9 45.3 0.2 0.0 34.9 0.1 0.0 0.0 0.0 0.2 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.2 13.6 0.7 0.0 0.0 0.0 10.6 0.0 0.0 1.0 0.1 0.0 0.0 0.0 1.9 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.7 0.1 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 4.1 0.0 7.0 14.5 0.0 0.0 1.1 5.1 1.1 0.0 0.4 3.5 0.3 0.6 2.8 18.1 0.3 5.1 3.3 3.0 2.5 3.2 2.6 4.9 5.9 4.7 5.3 4.0 5.9 7.5 1.9 0.0 0.0 0.0 0.9 0.9 0.0 0.0 0.0 0.0 0.1 0.3 2.2 1.5 0.6 0.0 0.0 0.4 17.3 0.0 0.0 0.0 0.1 0.0 0.7 5.8 0.0 2.7 0.5 0.0 0.5 7.8 0.0 0.0 0.0 0.0 11.4 0.6 32.4 0.0 0.4 0.0 0.0 69.6 2.5 0.3 0.3 27.1 3.6 39.4 7.6 0.0 30.9 1.0 0.0 0.0 0.0 5.3 0.8 0.0 0.0 0.0 0.7 0.1 6.6 4.1 5.1 0.0 0.0 0.1 0.6 0.5 2.2 0.5 0.0 0.0 CMPK1 "CMPK, UMP-CMPK" ENSG00000162368 "Cytidine/uridine monophosphate kinase 1" P30085 1 47333797-47378839 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053730, HPA058604" Approved Supported Nucleoplasm "Intracellular and membrane" NA NA 1400000 "Cluster 34: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm "HPA053730: AB_2682244, HPA058604: AB_2683773" "unprognostic (2.16e-2)" "unprognostic (1.16e-1)" "unprognostic (9.39e-3)" "unprognostic (1.18e-1)" "unprognostic (1.09e-3)" "unprognostic (1.50e-2)" "unprognostic (1.59e-2)" "unprognostic (9.88e-2)" "unprognostic (5.80e-2)" "unprognostic (2.90e-2)" "unprognostic (1.71e-2)" "unprognostic (2.61e-1)" "unprognostic (1.28e-2)" "unprognostic (2.58e-2)" "unprognostic (1.06e-1)" "unprognostic (1.02e-3)" "unprognostic (7.36e-2)" 88.2 45.2 47.0 64.2 50.6 53.1 102.2 51.9 73.1 74.8 49.8 134.1 163.9 44.2 42.2 108.2 35.2 88.5 63.3 44.5 56.9 78.7 217.2 63.8 71.8 52.6 52.4 38.1 90.9 57.7 32.9 48.8 54.2 95.0 141.0 29.2 157.4 50.7 71.1 65.1 152.5 56.0 52.6 58.0 109.0 17.5 52.3 61.7 92.0 73.9 87.9 80.6 63.8 55.3 124.9 68.4 86.6 77.9 154.6 179.3 122.5 216.4 129.8 128.6 129.9 61.3 84.1 183.4 108.6 147.9 120.5 82.7 64.8 112.1 174.9 279.5 52.7 142.9 91.0 106.7 100.8 206.2 100.2 101.2 132.7 107.5 119.7 121.1 135.2 67.4 137.3 143.5 169.8 45.9 168.2 96.8 55.1 162.9 93.6 103.4 149.8 138.5 126.5 134.9 78.3 41.3 155.0 177.7 128.9 113.7 44.2 121.0 127.7 159.6 92.7 154.5 180.8 103.8 154.3 124.4 126.3 125.3 111.7 43.3 12.8 24.2 16.1 14.0 20.7 13.6 18.0 20.0 13.5 14.3 16.9 16.4 5.3 19.4 17.0 11.4 20.9 15.6 47.0 50.6 51.9 73.1 44.5 56.9 52.6 52.4 54.2 52.6 52.3 55.3 101.7 70.5 54.4 14.4 148.1 175.5 125.3 88.9 102.4 34.2 167.8 67.7 48.9 147.3 87.0 75.4 16.7 82.3 117.9 280.0 174.1 186.8 1.6 56.2 63.3 83.8 117.5 126.0 28.5 181.6 133.0 91.2 125.4 98.2 94.0 39.7 88.5 235.9 75.9 43.7 30.2 326.6 91.6 122.0 265.0 5.0 59.4 107.1 254.3 31.9 100.5 66.9 124.6 20.6 25.0 146.8 168.6 70.0 119.8 203.5 234.6 254.5 112.3 31.1 85.5 75.9 95.8 14.0 29.8 167.0 195.1 118.3 160.5 49.0 240.2 250.8 CNBP "CNBP1, DM2, RNF163, ZCCHC22, ZNF9" ENSG00000169714 "CCHC-type zinc finger nucleic acid binding protein" P62633 3 129167827-129183922 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063097 Approved Nucleoplasm,Cytosol NA NA 160000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA063097: AB_2684939" "unprognostic (1.74e-1)" "unprognostic (3.11e-2)" "unprognostic (4.84e-1)" "unprognostic (3.35e-2)" "unprognostic (6.28e-2)" "unprognostic (7.38e-2)" "unprognostic (7.02e-3)" "unprognostic (1.23e-1)" "unprognostic (1.06e-3)" "unprognostic (6.39e-2)" "prognostic unfavorable (3.51e-4)" "unprognostic (4.72e-3)" "unprognostic (4.62e-3)" "unprognostic (1.89e-1)" "unprognostic (2.03e-1)" "unprognostic (2.51e-1)" "unprognostic (1.58e-1)" 292.7 308.2 175.2 181.1 184.0 254.1 274.6 198.6 211.3 295.9 175.7 314.1 198.5 285.8 197.6 264.6 275.7 195.1 487.2 170.6 184.3 231.6 433.7 258.3 251.0 182.7 175.1 385.8 307.4 277.9 169.5 214.3 187.1 256.6 219.0 231.8 250.8 282.4 1207.6 288.0 199.2 234.9 195.6 200.7 262.1 131.2 181.9 254.2 261.8 797.9 250.7 317.5 269.2 211.7 452.7 266.4 369.9 294.6 355.2 303.9 294.9 344.2 535.7 362.2 412.4 389.2 305.7 589.8 292.2 318.1 269.6 328.3 484.3 396.4 484.6 404.5 357.9 569.2 251.7 420.2 355.7 622.4 314.5 295.5 449.2 254.8 897.8 247.6 324.1 328.1 437.6 391.9 384.0 538.9 578.6 454.1 452.7 399.7 439.1 502.4 343.4 707.7 379.1 425.4 501.2 402.8 271.5 263.0 766.3 214.4 305.6 421.3 347.9 268.4 266.2 374.1 353.7 367.3 365.4 932.3 277.3 419.2 362.4 1077.7 810.5 930.9 551.8 596.8 699.0 691.0 658.8 595.3 552.8 603.8 700.3 610.5 1102.3 601.1 485.5 320.4 704.3 2029.8 175.2 184.0 198.6 211.3 170.6 184.3 182.7 175.1 187.1 195.6 181.9 211.7 253.7 259.6 263.9 27.1 292.8 524.7 417.0 262.9 259.6 153.7 177.5 272.5 608.0 141.5 235.1 79.1 33.3 252.3 188.1 143.9 373.7 226.9 36.0 141.4 195.1 267.5 171.3 246.5 28.2 290.7 396.6 309.4 142.8 172.8 314.5 173.0 167.0 138.5 246.5 92.5 33.7 178.6 140.4 194.4 463.0 42.9 316.0 232.4 318.4 35.6 392.7 350.3 236.9 32.6 42.8 230.1 158.0 319.7 311.7 405.1 196.5 237.4 164.8 153.8 263.0 343.6 571.0 305.2 271.5 286.5 586.7 291.7 304.2 277.7 213.6 376.2 CNNM3 ACDP3 ENSG00000168763 "Cyclin and CBS domain divalent metal cation transport mediator 3" Q8NE01 2 96816245-96835382 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 33.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016711 Supported Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA016711: AB_1847394" "unprognostic (1.50e-2)" "unprognostic (6.96e-2)" "unprognostic (2.71e-2)" "unprognostic (3.21e-2)" "unprognostic (1.82e-1)" "unprognostic (1.23e-1)" "unprognostic (2.14e-1)" "unprognostic (1.01e-1)" "unprognostic (3.03e-1)" "unprognostic (1.59e-1)" "unprognostic (8.32e-3)" "unprognostic (3.64e-1)" "unprognostic (5.31e-3)" "unprognostic (7.35e-2)" "unprognostic (3.36e-1)" "unprognostic (1.06e-1)" "unprognostic (4.48e-2)" 7.8 8.9 8.0 6.7 10.1 7.0 7.9 15.0 9.5 8.4 8.0 10.5 17.3 8.5 5.2 5.6 10.9 9.4 5.7 7.5 7.1 7.5 20.0 9.1 9.1 9.2 9.0 10.3 26.6 21.4 8.0 10.2 8.5 8.9 8.8 13.1 12.4 9.0 45.1 8.5 14.2 5.8 6.9 9.5 12.4 11.3 8.6 11.4 8.4 6.1 7.2 8.3 7.6 12.5 10.4 9.2 8.7 13.4 10.2 5.4 24.3 6.8 5.5 6.4 6.3 25.3 16.4 11.7 23.3 5.2 7.4 11.8 12.6 8.8 4.8 11.3 29.4 15.3 12.9 28.1 8.9 14.0 11.2 4.5 11.8 8.1 7.3 8.7 7.9 9.6 14.1 19.8 2.7 13.0 12.8 17.4 11.6 15.6 11.5 15.6 11.6 14.4 11.3 12.7 26.5 17.0 8.7 14.2 8.2 13.3 13.5 10.2 3.7 5.6 16.1 9.2 9.8 17.8 18.1 8.6 3.5 13.2 6.0 1.6 0.8 3.5 2.6 0.6 1.6 1.8 1.6 2.1 0.3 2.1 1.5 1.5 3.3 1.5 1.4 1.8 2.2 0.8 8.0 10.1 15.0 9.5 7.5 7.1 9.2 9.0 8.5 6.9 8.6 12.5 4.1 9.6 4.8 9.1 5.4 1.3 2.7 1.1 0.6 17.5 4.9 5.0 15.6 8.6 3.0 0.0 8.4 5.0 8.9 4.7 0.0 5.0 7.3 5.3 4.4 3.7 4.2 5.7 5.7 4.3 2.6 4.3 5.6 12.6 0.0 11.7 6.4 17.4 2.6 33.7 9.5 7.6 4.1 3.4 0.6 1.3 2.5 1.9 3.6 4.7 2.3 6.4 6.2 18.1 19.6 2.7 1.9 4.1 6.4 7.1 8.4 1.9 2.8 13.5 13.1 5.7 4.5 5.9 6.3 2.8 1.6 1.6 6.9 11.5 8.2 3.4 CNRIP1 "C2orf32, CRIP1, CRIP1a, CRIP1b, DKFZP566K1924" ENSG00000119865 "Cannabinoid receptor interacting protein 1" Q96F85 2 68284171-68320051 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 71.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 72.2;Erythroid cells: 116.2;granulocytes: 122.9" "Cancer enhanced" "Detected in all" "glioma: 14.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 109 "basophil: 12.2" "Lineage enriched" "Detected in single" 109 "granulocytes: 12.2" "Cell line enhanced" "Detected in many" "HEL: 158.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035337 Approved Cytosol NA NA 54000 "Cluster 38: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA035337: AB_10601359" "unprognostic (1.23e-1)" "unprognostic (8.88e-2)" "unprognostic (1.32e-1)" "unprognostic (2.85e-1)" "unprognostic (1.31e-1)" "unprognostic (1.20e-1)" "unprognostic (6.51e-2)" "unprognostic (3.52e-2)" "unprognostic (2.86e-2)" "unprognostic (4.58e-2)" "unprognostic (4.71e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.04e-2)" "unprognostic (3.63e-2)" "unprognostic (1.69e-1)" "unprognostic (3.38e-3)" 27.4 6.4 59.0 5.9 62.3 6.1 20.2 50.9 71.6 30.1 29.6 17.1 3.5 22.4 6.1 5.3 24.2 8.5 16.0 65.1 51.8 10.3 2.9 18.3 5.1 40.4 45.1 31.2 3.0 1.8 15.4 12.1 44.3 15.1 4.6 29.6 5.8 8.9 6.6 8.1 10.9 9.3 44.7 10.2 10.6 2.6 52.7 2.7 8.9 7.0 2.9 20.7 19.2 51.8 0.0 1.1 9.0 0.0 34.1 24.6 0.1 34.5 26.6 30.6 22.3 0.0 0.0 0.0 1.2 33.2 22.6 0.0 0.7 0.2 32.6 0.0 8.1 158.7 2.3 0.0 34.7 0.1 21.7 22.1 0.0 20.0 11.5 18.7 47.8 0.0 0.2 0.1 23.4 0.1 0.0 0.4 16.3 0.0 15.6 0.0 13.2 0.0 0.0 0.0 45.8 47.8 2.2 0.0 28.3 0.1 0.0 1.7 51.4 21.1 12.9 18.5 51.0 0.0 0.0 0.1 16.9 0.0 15.5 12.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 59.0 62.3 50.9 71.6 65.1 51.8 40.4 45.1 44.3 44.7 52.7 51.8 50.2 0.0 4.3 15.0 0.6 12.9 0.4 0.0 4.6 72.2 0.6 1.7 2.1 0.0 0.6 0.0 22.9 1.2 0.1 0.0 0.0 0.4 0.7 1.9 30.4 60.6 0.0 116.2 48.8 0.2 9.3 44.4 0.5 0.6 122.9 1.3 36.4 0.8 56.3 28.6 39.5 0.0 0.0 25.7 40.9 2.6 45.4 13.9 37.4 16.9 2.5 42.0 0.0 24.1 19.6 0.5 0.0 42.5 0.5 1.2 0.0 0.1 0.0 54.3 46.0 18.7 41.9 0.7 0.5 0.7 10.7 2.1 3.8 27.3 0.0 1.0 COA3 "CCDC56, COX25, HSPC009, MITRAC12" ENSG00000183978 "Cytochrome c oxidase assembly factor 3" Q9Y2R0 17 42795147-42798704 "Disease related genes, Predicted membrane proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 710.2;Proximal tubular cells: 729.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031966, HPA071122" Approved Enhanced Mitochondria NA NA 13000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA031966: AB_10602115, HPA071122: " "unprognostic (1.20e-1)" "prognostic favorable (3.40e-4)" "unprognostic (5.65e-2)" "prognostic favorable (8.93e-4)" "unprognostic (7.62e-2)" "unprognostic (2.19e-1)" "unprognostic (4.78e-2)" "unprognostic (1.16e-2)" "unprognostic (1.48e-1)" "unprognostic (2.25e-2)" "unprognostic (8.44e-3)" "unprognostic (1.52e-1)" "prognostic favorable (6.62e-4)" "unprognostic (1.64e-1)" "unprognostic (2.70e-1)" "unprognostic (3.16e-2)" "unprognostic (3.01e-2)" 64.8 73.0 122.8 30.8 122.9 15.3 63.7 128.2 160.5 71.5 125.8 110.8 106.0 55.6 172.3 128.4 73.7 42.9 102.4 125.6 124.5 223.4 158.9 45.7 41.0 124.6 125.4 55.8 172.6 106.8 59.7 38.9 127.2 84.9 89.7 34.9 66.1 66.7 119.6 58.0 81.1 41.5 125.8 50.5 128.5 25.2 125.5 42.7 57.9 94.3 49.8 60.5 78.6 125.3 66.8 219.9 99.4 54.7 89.5 75.8 61.0 51.1 77.2 119.2 107.3 87.5 81.8 3.9 141.0 62.5 112.4 63.5 77.3 124.8 111.9 65.1 202.8 44.7 96.3 280.8 63.4 61.0 52.0 77.4 92.0 112.7 64.2 61.0 96.1 31.6 72.9 55.5 106.9 108.9 20.2 132.9 45.7 135.9 78.5 79.4 145.1 113.6 122.6 90.2 73.8 61.9 52.2 54.9 91.5 85.3 170.3 78.5 59.3 129.6 67.5 55.4 69.0 65.1 76.3 36.2 97.3 60.1 89.8 206.7 209.6 141.5 136.2 208.1 143.5 218.9 140.0 138.3 178.8 187.5 128.4 126.2 22.7 187.5 177.7 120.3 191.1 245.9 122.8 122.9 128.2 160.5 125.6 124.5 124.6 125.4 127.2 125.8 125.5 125.3 55.4 28.9 68.7 7.5 44.5 36.8 52.2 192.7 50.7 36.5 99.9 110.9 263.9 173.0 113.8 266.7 20.9 153.9 30.3 233.8 710.2 136.5 13.2 203.0 70.0 65.4 79.9 54.3 8.1 239.8 177.5 72.5 103.5 154.6 35.5 77.5 69.3 390.1 121.6 45.4 9.2 205.9 195.3 75.3 33.4 18.8 55.9 54.8 88.9 6.5 86.0 94.7 63.8 6.6 11.8 134.7 201.6 45.1 73.2 79.0 221.7 729.1 145.2 37.0 39.5 46.2 88.0 48.4 52.1 242.0 55.5 102.2 43.4 97.6 258.9 67.7 COL13A1 ENSG00000197467 "Collagen type XIII alpha 1 chain" Q5TAT6 10 69801880-69964275 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Osteogenesis" "Developmental protein, Heparin-binding" "Congenital myasthenic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 30.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 10.1;granulocytes: 20.3;Melanocytes: 5.4;Microglial cells: 6.5;NK-cells: 9.2;Smooth muscle cells: 5.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 63.6;BJ hTERT+: 61.6;hTERT-RPE1: 83.7;HUVEC TERT2: 102.2;PC-3: 93.1;TIME: 137.4" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA050392 Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "HPA050392: AB_2681110" "unprognostic (2.79e-2)" "unprognostic (2.82e-3)" "unprognostic (1.38e-1)" "unprognostic (3.86e-1)" "unprognostic (4.67e-4)" "unprognostic (3.13e-1)" "unprognostic (1.69e-1)" "unprognostic (7.43e-2)" "unprognostic (6.16e-3)" "unprognostic (1.22e-1)" "unprognostic (2.60e-1)" "unprognostic (2.53e-2)" "unprognostic (1.36e-5)" "unprognostic (2.66e-1)" "unprognostic (2.32e-1)" "unprognostic (1.52e-2)" "unprognostic (3.93e-2)" 1.2 1.9 1.5 2.6 1.7 0.3 2.0 9.5 3.3 5.7 1.9 4.6 2.9 1.8 30.4 1.9 2.8 2.4 3.4 1.4 1.5 2.0 0.8 10.9 0.9 1.6 1.6 0.9 2.1 0.8 3.7 1.7 1.8 13.6 3.4 0.0 0.7 8.0 0.9 5.2 3.8 2.9 1.6 8.0 6.2 0.7 1.7 0.3 1.5 1.4 0.8 3.8 1.8 1.5 1.5 0.6 22.1 0.0 0.1 4.3 0.1 63.6 61.6 10.9 5.5 0.0 1.4 0.2 10.5 30.1 1.0 2.3 0.0 0.2 18.9 0.0 1.6 0.0 0.0 0.0 2.9 0.0 0.1 9.8 0.1 27.5 9.0 83.7 102.2 0.0 0.0 0.1 10.4 0.4 0.0 0.2 5.3 0.0 93.1 0.1 0.0 10.3 0.4 0.0 2.4 0.0 0.0 0.2 3.4 0.9 0.0 0.2 137.4 0.3 17.1 5.7 45.7 13.4 0.0 0.1 37.2 0.1 51.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 1.5 1.7 9.5 3.3 1.4 1.5 1.6 1.6 1.8 1.6 1.7 1.5 0.9 0.0 0.6 0.3 0.0 3.4 0.3 0.3 0.6 0.2 0.1 2.0 2.1 0.0 0.5 0.0 0.0 0.0 1.2 0.0 0.0 1.3 0.0 0.0 0.2 3.4 0.0 0.0 1.4 0.0 0.0 10.1 0.0 0.1 20.3 1.8 1.1 0.0 0.1 0.0 0.3 0.0 0.0 0.3 2.3 0.0 0.0 0.3 5.4 6.5 0.0 0.1 9.2 0.0 0.3 0.1 0.0 0.4 0.3 0.5 0.9 0.0 0.1 0.0 0.0 1.1 5.6 0.5 0.5 0.2 3.0 0.1 0.6 0.5 0.1 0.1 COL16A1 ENSG00000084636 "Collagen type XVI alpha 1 chain" Q07092 1 31652263-31704319 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 109.0;Oligodendrocyte precursor cells: 62.4;Oligodendrocytes: 122.0;Peritubular cells: 91.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 133.1;ASC TERT1: 102.9;BJ hTERT+: 115.9;fHDF/TERT166: 106.5;HSkMC: 98.7;U-2197: 92.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA027237 Uncertain "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 960000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "HPA027237: AB_10600699" "unprognostic (2.25e-2)" "unprognostic (9.88e-2)" "unprognostic (5.64e-2)" "unprognostic (8.43e-2)" "prognostic unfavorable (8.08e-4)" "unprognostic (1.00e-1)" "unprognostic (3.99e-2)" "unprognostic (2.04e-1)" "unprognostic (4.48e-3)" "unprognostic (1.66e-3)" "unprognostic (1.44e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (4.00e-9)" "unprognostic (9.62e-2)" "unprognostic (6.13e-2)" "unprognostic (4.60e-2)" "unprognostic (2.15e-2)" 33.6 17.3 19.0 14.4 44.7 0.3 41.0 35.9 32.4 169.7 7.6 78.9 14.8 93.6 23.7 22.4 37.4 39.4 33.6 18.9 29.8 11.5 3.2 31.1 8.5 55.5 43.2 177.9 7.8 3.5 28.6 21.1 48.6 102.8 10.9 8.8 35.5 91.3 8.4 69.3 35.8 56.2 34.0 9.9 42.1 40.9 40.3 5.6 46.8 7.4 4.1 106.9 86.8 57.5 0.1 2.0 0.0 0.1 133.1 102.9 14.6 60.5 115.9 15.1 16.1 0.4 11.0 0.0 1.9 106.5 2.3 48.3 0.0 65.8 3.5 0.0 0.2 0.0 8.1 21.3 45.1 0.0 0.3 98.7 44.6 43.2 22.7 3.8 0.1 0.3 0.0 0.2 2.1 0.0 0.1 0.5 0.1 0.4 0.2 0.2 1.3 0.4 0.0 0.4 1.5 2.7 7.3 1.2 9.6 0.5 1.2 0.0 0.2 52.3 52.5 92.1 1.3 0.1 0.2 0.0 36.1 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 44.7 35.9 32.4 18.9 29.8 55.5 43.2 48.6 34.0 40.3 57.5 4.3 9.6 3.9 109.0 0.1 30.7 14.8 37.5 15.9 2.4 7.9 21.3 8.4 0.0 9.8 18.4 2.1 1.9 0.6 2.0 0.0 4.6 13.6 2.6 11.5 2.8 27.6 0.4 23.9 0.7 3.8 54.3 8.2 2.4 7.0 0.2 5.0 0.0 1.3 0.0 8.2 30.9 8.2 0.6 11.4 26.8 43.8 0.7 14.2 10.3 0.0 31.3 0.0 62.4 122.0 1.2 4.7 91.4 0.3 9.3 16.8 2.1 15.0 2.5 0.0 5.4 25.0 14.9 3.8 1.9 21.2 2.2 2.2 0.5 6.8 15.3 COL18A1 "KNO, KNO1, KS" ENSG00000182871 "Collagen type XVIII alpha 1 chain" P39060 21 45405165-45513720 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 561.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 479.6;Sertoli cells: 223.5;Smooth muscle cells: 268.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 3.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Cell line enhanced" "Detected in many" "BJ hTERT+: 139.0;EFO-21: 309.4;NTERA-2: 170.6;RPTEC TERT1: 131.6;TIME: 186.0" "Region enriched" "Detected in all" 6 "cerebellum: 22.1" "Low region specificity" "Detected in all" "HPA030933, HPA036104" Supported Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA 290000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "HPA030933: , HPA036104: AB_2674943" "unprognostic (4.32e-2)" "unprognostic (1.20e-1)" "unprognostic (1.76e-2)" "unprognostic (3.47e-2)" "unprognostic (3.25e-2)" "unprognostic (5.55e-2)" "prognostic favorable (6.16e-4)" "unprognostic (4.23e-3)" "unprognostic (9.93e-2)" "unprognostic (3.48e-1)" "unprognostic (2.77e-1)" "unprognostic (5.50e-2)" "unprognostic (1.70e-1)" "unprognostic (1.83e-2)" "unprognostic (9.44e-2)" "unprognostic (9.10e-3)" "unprognostic (2.25e-3)" 136.4 87.6 14.5 33.9 22.3 15.9 97.1 26.4 21.8 229.4 34.4 91.2 30.4 135.6 35.4 50.1 118.3 28.9 122.2 15.7 18.1 218.2 561.9 83.2 19.8 43.7 28.6 257.3 102.3 7.9 106.5 40.7 39.1 91.0 5.5 5.4 35.8 46.8 26.5 77.8 65.7 28.5 26.6 86.8 44.5 30.0 27.0 9.0 101.1 7.4 7.2 109.8 112.2 45.4 10.5 84.0 20.6 18.0 38.6 31.9 3.3 82.0 139.0 39.1 10.5 48.8 28.9 1.5 309.4 82.8 21.6 37.9 4.6 5.0 7.4 0.7 20.0 47.9 1.4 69.6 37.3 0.7 4.4 37.6 3.3 3.8 4.5 8.5 121.3 0.5 49.6 0.3 14.4 16.7 0.8 3.2 170.6 3.2 30.7 0.7 12.6 4.0 131.6 1.3 22.8 16.3 7.6 7.8 26.6 73.0 7.5 9.9 186.0 0.5 11.4 0.4 17.7 0.4 0.8 1.5 0.1 1.7 32.7 0.8 0.1 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.2 3.2 0.0 0.0 0.1 0.0 0.1 14.5 22.3 26.4 21.8 15.7 18.1 43.7 28.6 39.1 26.6 27.0 45.4 156.9 0.0 4.1 6.5 3.9 67.7 15.5 19.0 67.7 13.5 9.3 32.1 15.7 61.5 5.0 112.2 4.2 1.9 3.4 0.1 9.8 117.5 1.5 58.3 99.5 91.2 0.0 33.0 4.9 5.8 1.1 101.1 3.6 144.2 57.8 6.6 75.0 479.6 2.4 0.0 15.8 0.1 4.1 12.1 32.5 6.7 79.9 6.5 49.8 82.4 3.2 141.9 7.2 4.0 28.0 9.9 0.0 126.0 4.6 14.0 0.0 72.9 0.7 6.3 223.5 138.2 268.6 4.1 6.0 7.9 28.6 2.5 15.3 47.5 0.4 2.6 COL4A2 "DKFZp686I14213, FLJ22259" ENSG00000134871 "Collagen type IV alpha 2 chain" P08572 13 110305812-110513209 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 474.0" "Cell type enhanced" "Detected in many" "Adipocytes: 313.6;Endometrial stromal cells: 308.3;Endothelial cells: 278.2;Extravillous trophoblasts: 512.9;Granulosa cells: 223.8;Sertoli cells: 374.7;Smooth muscle cells: 338.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 1041.3;WM-115: 428.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010751, HPA029118, HPA069337" Enhanced Supported Vesicles "Secreted to extracellular matrix" NA NA 2700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "CAB010751: AB_476828, HPA029118: , HPA069337: " "unprognostic (2.43e-1)" "unprognostic (4.13e-3)" "unprognostic (8.04e-2)" "unprognostic (6.03e-3)" "unprognostic (2.20e-1)" "unprognostic (2.64e-2)" "unprognostic (3.45e-2)" "unprognostic (1.15e-2)" "unprognostic (3.50e-2)" "unprognostic (1.78e-1)" "unprognostic (1.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.49e-5)" "unprognostic (1.33e-2)" "unprognostic (1.57e-2)" "unprognostic (6.95e-2)" "prognostic unfavorable (9.25e-4)" 240.5 51.2 15.1 103.5 2.3 0.6 153.5 1.7 5.9 111.6 3.4 282.0 29.5 219.4 10.4 51.8 122.9 84.2 113.0 19.3 1.8 71.7 19.1 181.7 22.8 4.3 7.8 51.9 32.6 25.6 17.5 474.0 6.0 121.3 18.9 2.8 35.0 95.8 44.7 45.2 84.1 226.8 2.6 121.5 96.4 15.7 11.5 7.9 74.9 21.5 7.1 186.2 74.4 2.9 88.9 45.7 218.7 0.6 213.7 99.0 312.8 307.9 97.4 167.3 76.1 2.5 0.7 0.6 1041.3 60.0 75.0 85.4 0.1 82.4 27.3 28.1 46.3 0.2 76.6 0.7 150.5 0.5 1.0 42.8 4.5 114.8 71.2 193.5 158.5 0.0 1.3 0.9 25.4 0.3 0.3 12.1 34.2 0.8 11.7 0.6 87.8 0.4 125.6 0.0 6.4 35.4 0.3 0.9 81.2 84.7 0.6 6.7 327.7 94.9 237.9 2.3 161.9 0.6 3.0 7.4 5.8 0.4 428.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 2.3 1.7 5.9 19.3 1.8 4.3 7.8 6.0 2.6 11.5 2.9 313.6 83.3 5.8 17.9 2.9 9.6 8.0 16.3 1.8 2.4 7.0 56.8 31.8 20.0 1.8 53.3 0.0 77.4 0.1 10.0 1.9 39.0 1.7 19.4 308.3 278.2 0.0 8.0 17.7 4.4 512.9 159.1 5.6 50.1 1.3 223.8 102.1 1.8 30.9 0.0 44.0 7.0 2.0 3.3 13.3 3.4 60.6 3.8 39.2 46.9 2.0 7.3 0.0 5.5 1.1 2.8 1.4 176.0 1.5 12.3 23.9 32.7 2.1 0.3 374.7 64.7 338.9 0.9 8.5 0.7 7.0 67.2 3.6 49.4 5.4 2.4 COL4A4 CA44 ENSG00000081052 "Collagen type IV alpha 4 chain" P53420 2 227002714-227164453 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Collecting duct cells: 46.0;Cone photoreceptor cells: 56.3;Granulosa cells: 62.6;Muller glia cells: 78.6;Oligodendrocyte precursor cells: 55.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 4.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "memory B-cell: 4.1" "Lineage enriched" "Detected in single" 5 "B-cells: 4.1" "Cell line enhanced" "Detected in some" "HeLa: 34.3;hTERT-RPE1: 27.2;Karpas-707: 8.9;RPTEC TERT1: 14.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (7.31e-2)" "unprognostic (7.56e-2)" "unprognostic (6.65e-2)" "unprognostic (4.88e-5)" "unprognostic (1.12e-1)" "unprognostic (2.92e-2)" "unprognostic (8.50e-3)" "unprognostic (5.14e-2)" "unprognostic (1.44e-1)" "unprognostic (1.69e-2)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "prognostic favorable (2.30e-13)" "unprognostic (1.53e-2)" "unprognostic (2.65e-1)" "unprognostic (1.30e-1)" "unprognostic (4.15e-2)" 1.0 6.9 1.3 2.1 1.1 0.1 0.7 0.9 0.9 0.5 14.2 0.9 0.9 2.0 7.2 1.1 2.1 4.4 9.2 1.0 1.3 14.0 1.6 8.3 2.8 3.1 2.2 2.0 5.5 0.6 10.2 0.3 2.6 4.5 0.8 8.4 0.7 8.3 6.9 0.3 2.4 1.6 1.5 1.9 1.2 1.3 4.4 0.9 9.9 5.7 4.5 2.9 0.9 1.3 0.0 0.8 0.0 0.0 0.1 0.2 0.0 0.3 0.2 0.1 0.6 0.0 0.7 0.0 1.7 0.0 0.7 0.1 3.1 1.1 0.2 0.0 3.4 0.0 34.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 27.2 0.0 1.1 0.0 8.9 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.9 14.5 5.6 0.8 0.0 2.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 2.7 0.0 0.3 6.7 5.3 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.3 0.0 0.0 4.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.3 1.1 0.9 0.9 1.0 1.3 3.1 2.2 2.6 1.5 4.4 1.3 2.0 73.7 24.1 3.6 11.1 0.5 0.4 0.2 0.0 29.1 0.5 1.3 3.5 8.6 6.2 46.0 56.3 0.0 1.4 0.1 1.9 0.3 0.8 0.3 1.8 5.2 1.2 0.0 2.5 3.8 0.0 8.1 1.5 0.9 0.0 62.6 2.5 0.7 0.1 0.0 10.4 0.1 2.0 0.3 1.5 4.3 25.1 0.8 0.0 12.2 0.0 78.6 0.0 55.3 3.4 4.1 0.1 27.1 14.9 0.2 0.0 3.6 0.0 8.5 0.0 16.8 8.6 0.1 0.6 0.2 0.0 0.0 1.4 0.9 0.3 0.1 COL5A2 ENSG00000204262 "Collagen type V alpha 2 chain" P05997 2 189031898-189225312 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 186.0;Excitatory neurons: 185.2;Fibroblasts: 145.7;Skeletal myocytes: 76.4;Smooth muscle cells: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 447.8;BJ hTERT+ SV40 Large T+ RasG12V: 382.4;fHDF/TERT166: 430.3;HSkMC: 340.2;SuSa: 373.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 820000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (7.45e-2)" "unprognostic (6.44e-3)" "unprognostic (1.22e-1)" "unprognostic (9.31e-2)" "unprognostic (2.01e-1)" "unprognostic (1.13e-1)" "unprognostic (6.28e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (5.97e-2)" "unprognostic (1.78e-2)" "unprognostic (4.44e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.53e-10)" "unprognostic (4.57e-3)" "unprognostic (3.76e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (3.58e-4)" 61.0 4.8 2.3 42.5 5.7 0.2 25.7 0.0 15.6 83.4 3.1 48.7 10.0 43.4 32.7 23.6 21.2 81.9 19.5 17.6 0.8 6.3 12.4 26.1 9.3 2.0 17.4 25.2 7.1 7.5 7.3 111.5 3.8 14.8 25.4 1.6 7.4 12.8 7.8 12.9 22.8 98.3 1.9 10.0 21.5 6.8 1.0 4.7 9.8 26.8 10.3 57.3 29.7 2.5 0.4 93.5 143.9 67.5 212.0 285.3 0.8 213.7 242.3 447.8 382.4 63.2 0.7 0.2 2.2 430.3 23.2 1.6 4.1 2.3 153.3 0.9 1.3 1.0 2.1 0.6 282.6 0.6 0.4 340.2 7.8 129.8 45.3 92.2 108.5 0.9 0.5 0.4 109.1 2.4 0.3 0.3 20.9 0.9 124.3 0.5 33.9 0.4 0.5 24.9 2.0 1.4 5.2 2.5 5.2 373.0 2.1 0.2 91.6 212.8 22.9 52.6 44.6 0.8 0.4 0.6 32.2 0.1 235.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 5.7 0.0 15.6 17.6 0.8 2.0 17.4 3.8 1.9 1.0 2.5 36.7 0.0 1.5 29.7 0.3 26.1 0.2 7.2 6.2 1.3 1.6 3.7 2.8 0.0 0.7 1.8 0.0 4.6 0.2 0.5 1.9 0.6 0.7 22.4 186.0 9.1 38.7 0.0 185.2 0.7 3.9 145.7 0.5 5.1 0.0 4.2 25.7 7.4 6.6 0.0 23.8 0.2 4.1 0.3 27.4 1.7 48.7 1.4 21.4 25.3 0.6 0.7 0.0 21.6 10.9 1.1 0.1 19.5 0.4 0.3 0.1 1.0 1.9 0.8 46.0 76.4 116.0 3.9 1.8 2.0 18.8 6.2 2.8 27.4 0.0 0.4 COL6A3 ENSG00000163359 "Collagen type VI alpha 3 chain" P12111 2 237324003-237414207 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Congenital muscular dystrophy, Disease variant, Dystonia, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 391.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 355.2;Fibroblasts: 567.9;Leydig cells: 315.1;Smooth muscle cells: 197.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 3311.7;ASC TERT1: 4227.5;BJ hTERT+: 1279.6;HSkMC: 2705.3" "Region enhanced" "Detected in some" "basal ganglia: 4.5" "Region enriched" "Detected in many" 4 "spinal cord: 12.0" "HPA010007, HPA010080" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 1000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA010007: , HPA010080: AB_1078550" "unprognostic (8.94e-2)" "unprognostic (7.24e-2)" "unprognostic (6.60e-2)" "unprognostic (3.82e-1)" "unprognostic (3.90e-2)" "unprognostic (2.37e-1)" "unprognostic (5.34e-2)" "unprognostic (2.87e-2)" "unprognostic (8.20e-3)" "unprognostic (2.55e-2)" "unprognostic (1.33e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (5.57e-11)" "unprognostic (1.54e-2)" "unprognostic (2.50e-2)" "unprognostic (3.51e-2)" "unprognostic (1.84e-3)" 150.8 8.3 0.1 126.5 1.0 0.4 74.5 0.2 3.0 212.6 5.2 94.8 22.9 156.3 10.2 44.1 91.8 236.4 61.2 2.4 0.1 5.7 10.3 65.8 30.7 0.6 0.1 123.8 21.1 17.3 2.8 132.9 0.7 47.7 51.7 0.0 45.2 55.4 32.5 35.7 46.6 391.3 0.8 19.0 41.5 15.6 1.8 24.8 38.1 62.3 16.1 188.4 62.7 0.9 0.2 0.5 0.6 0.0 3311.7 4227.5 60.9 815.6 1279.6 167.0 188.2 0.0 0.1 4.5 0.1 818.7 67.4 0.6 0.7 0.9 98.8 2.0 0.1 0.0 0.0 0.0 669.9 0.0 0.4 2705.3 0.0 596.3 1.8 7.8 0.2 0.0 0.1 0.6 6.2 0.0 0.1 0.2 0.5 0.0 7.4 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.4 17.3 0.0 0.4 2.9 19.0 45.1 27.6 142.4 1.0 0.0 0.1 859.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.2 3.0 2.4 0.1 0.6 0.1 0.7 0.8 1.8 0.9 48.2 0.0 10.5 0.3 0.6 61.1 0.5 0.5 1.8 1.0 2.5 2.9 10.6 1.5 3.8 0.0 0.0 4.5 1.2 0.0 0.0 0.9 5.4 11.0 355.2 17.6 0.0 0.0 0.8 0.0 6.2 567.9 6.6 8.7 1.3 1.8 25.4 1.8 8.1 0.0 0.4 0.0 0.0 1.3 85.4 9.6 315.1 5.5 72.9 29.0 2.2 1.1 1.0 0.0 0.3 2.4 0.0 103.4 2.0 0.9 0.0 0.2 1.0 2.3 32.9 19.2 197.7 1.5 1.3 3.3 61.5 5.7 9.3 48.7 0.0 1.0 COL8A2 "FECD, FECD1, PPCD, PPCD2" ENSG00000171812 "Collagen type VIII alpha 2 chain" P25067 1 36095239-36125222 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 10.2;Cardiomyocytes: 13.5;Fibroblasts: 13.4;Macrophages: 6.8;Melanocytes: 7.2;Microglial cells: 8.4;Sertoli cells: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 5.8;fHDF/TERT166: 4.3;HHSteC: 14.1;hTERT-RPE1: 18.2;THP-1: 4.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "spinal cord: 3.6" HPA049788 Uncertain Uncertain "Golgi apparatus" "Secreted to extracellular matrix" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA049788: AB_2680882" "unprognostic (9.98e-2)" "unprognostic (3.26e-2)" "unprognostic (2.51e-2)" "unprognostic (8.41e-3)" "unprognostic (8.76e-2)" "prognostic favorable (9.44e-4)" "unprognostic (1.15e-1)" "unprognostic (1.75e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (7.26e-4)" "unprognostic (3.50e-2)" "unprognostic (3.01e-1)" "prognostic unfavorable (9.35e-5)" "unprognostic (1.08e-2)" "unprognostic (6.77e-2)" "unprognostic (2.24e-2)" "unprognostic (1.16e-3)" 5.2 1.2 2.5 4.4 2.2 0.5 5.6 6.1 2.4 9.0 18.3 5.9 1.4 5.7 1.6 5.8 4.2 4.8 5.4 2.3 2.9 1.1 0.6 4.6 3.1 9.0 4.2 3.3 0.8 0.7 4.0 12.8 7.1 6.1 2.0 0.4 7.4 11.4 0.6 5.5 2.4 3.7 6.1 8.5 9.1 0.9 4.2 4.9 7.5 2.1 3.5 13.3 5.9 5.7 0.0 0.0 0.0 0.0 0.5 1.0 0.1 5.8 1.7 1.6 0.9 0.2 0.1 0.0 0.8 4.3 0.0 0.3 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.1 14.1 0.0 0.0 1.7 0.1 0.7 0.0 18.2 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.4 0.1 0.1 0.0 0.5 0.5 0.5 0.0 0.2 0.4 0.0 4.7 0.1 2.3 0.3 0.4 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.5 2.2 6.1 2.4 2.3 2.9 9.0 4.2 7.1 6.1 4.2 5.7 0.6 0.0 1.8 0.3 0.0 2.2 2.2 1.8 0.0 0.1 1.3 10.2 13.5 0.0 0.7 0.0 0.0 0.4 1.4 0.0 0.0 0.4 0.1 0.2 0.2 0.7 0.0 0.0 0.2 0.2 0.3 13.4 0.5 0.3 2.5 0.5 1.1 0.0 6.2 0.0 0.4 0.0 0.0 2.0 2.7 0.2 3.1 6.8 7.2 8.4 1.2 0.3 0.0 0.5 0.1 0.6 0.0 6.0 0.1 5.3 0.0 0.0 0.2 0.2 6.6 0.7 1.4 0.0 0.3 0.1 1.3 0.8 1.2 0.3 0.0 0.4 COLEC12 "CL-P1, SCARA4, SRCL" ENSG00000158270 "Collectin subfamily member 12" Q5KU26 18 316737-500722 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 31.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 104.4;Cytotrophoblasts: 149.0;Fibroblasts: 79.6;Hofbauer cells: 155.9;Microglial cells: 245.4;Muller glia cells: 74.5;Syncytiotrophoblasts: 111.2" "Cancer enhanced" "Detected in all" "prostate cancer: 14.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 24.3;BJ: 12.1;HSkMC: 20.0;U-2197: 31.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047917, HPA071056" Enhanced Approved "Golgi apparatus,Vesicles,Cell Junctions" NA NA 580000 "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "Cell Junctions" "HPA047917: AB_2680208, HPA071056: AB_2686338" "unprognostic (8.67e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-2)" "unprognostic (3.60e-2)" "unprognostic (6.94e-2)" "unprognostic (1.09e-2)" "unprognostic (1.14e-4)" "unprognostic (2.21e-1)" "unprognostic (1.21e-1)" "unprognostic (4.86e-2)" "unprognostic (1.32e-2)" "unprognostic (1.53e-1)" "unprognostic (2.61e-1)" "unprognostic (2.24e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (3.01e-3)" 12.4 1.7 5.1 2.4 4.8 0.2 5.5 4.7 5.7 31.6 9.7 5.5 1.5 9.0 1.0 2.0 6.5 4.4 6.6 4.6 7.2 2.4 0.3 11.4 2.0 7.7 6.5 2.0 1.1 0.9 0.9 20.0 5.2 4.0 2.4 5.3 4.1 1.4 3.1 3.6 3.5 5.1 4.3 0.3 3.4 1.4 6.5 1.3 5.2 2.0 2.5 8.1 4.0 5.5 0.0 0.0 2.1 0.0 2.3 24.3 0.8 12.1 4.2 1.7 3.1 0.0 0.0 0.0 0.1 2.0 0.1 0.0 0.3 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.1 0.0 0.0 20.0 0.0 1.0 0.0 0.7 4.7 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.7 0.0 6.5 0.0 0.0 0.1 0.3 0.0 0.1 0.0 1.9 0.1 0.0 0.0 2.8 0.4 31.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.1 0.1 0.0 0.0 5.1 4.8 4.7 5.7 4.6 7.2 7.7 6.5 5.2 4.3 6.5 5.5 6.8 3.2 104.4 34.3 2.1 4.1 3.2 0.0 1.2 6.4 2.6 1.7 4.0 2.8 10.7 3.7 10.4 149.0 1.4 0.3 0.0 0.2 11.1 0.5 3.9 15.8 15.7 2.7 0.5 0.0 5.3 79.6 0.0 0.8 13.9 1.2 5.7 0.4 155.9 6.7 1.4 1.0 0.0 4.9 8.9 31.4 61.5 32.1 1.8 245.4 16.2 74.5 3.1 2.0 10.4 0.3 0.6 7.2 1.2 6.5 1.4 0.2 1.7 12.4 0.0 13.2 21.6 1.3 2.5 1.8 3.8 111.2 4.8 11.6 0.8 1.3 COQ10A FLJ32452 ENSG00000135469 "Coenzyme Q10A" Q96MF6 12 56266890-56270966 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "heart muscle: 166.3;skeletal muscle: 280.7;tongue: 387.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 120.5;Distal tubular cells: 52.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068931 Approved "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 24: NB-4 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "Endoplasmic reticulum, Golgi apparatus" "HPA068931: AB_2686061" "unprognostic (4.55e-2)" "unprognostic (4.88e-3)" "prognostic unfavorable (5.46e-4)" "unprognostic (8.99e-3)" "unprognostic (2.77e-2)" "unprognostic (5.63e-2)" "unprognostic (3.11e-1)" "unprognostic (2.86e-3)" "unprognostic (6.09e-2)" "unprognostic (8.57e-2)" "prognostic favorable (2.06e-4)" "unprognostic (5.03e-2)" "prognostic favorable (3.44e-4)" "unprognostic (1.67e-1)" "unprognostic (8.07e-2)" "unprognostic (7.20e-2)" "unprognostic (1.15e-1)" 7.0 33.3 16.3 3.5 16.9 4.6 7.2 17.7 19.7 9.1 21.1 9.5 3.2 10.0 16.2 9.0 10.8 6.3 166.3 16.2 17.6 17.1 37.0 6.7 7.8 16.5 18.3 10.2 18.0 15.7 25.4 2.7 17.2 11.9 5.0 26.0 12.6 9.8 280.7 5.0 9.7 7.2 16.4 12.2 8.8 6.8 18.6 7.9 10.3 387.5 8.9 8.5 6.8 15.8 3.7 15.2 14.4 9.4 8.1 8.0 6.0 5.2 12.5 18.3 18.2 11.9 5.6 21.5 11.3 13.3 5.1 3.5 16.8 3.0 10.9 3.2 17.0 10.2 14.1 12.4 11.0 8.1 5.9 8.4 4.9 13.6 5.3 11.4 9.8 14.9 6.8 8.8 17.1 5.1 11.7 29.1 12.0 2.7 8.7 24.2 15.6 14.5 10.1 2.2 20.5 22.0 18.1 3.8 5.8 10.6 5.8 8.9 6.9 3.4 10.0 9.5 5.3 18.1 20.4 10.8 10.2 7.6 2.6 14.1 1.1 1.1 7.4 1.0 7.4 12.7 7.0 7.8 1.7 6.8 8.3 8.1 0.4 5.8 0.9 6.9 5.1 3.9 16.3 16.9 17.7 19.7 16.2 17.6 16.5 18.3 17.2 16.4 18.6 15.8 8.1 3.2 7.2 12.4 20.8 13.4 13.0 2.3 15.4 17.9 8.4 12.7 120.5 7.2 3.2 11.0 16.7 5.8 32.0 2.0 52.8 2.8 0.2 13.7 6.3 9.6 16.2 4.2 3.9 4.6 6.8 10.9 6.6 5.1 4.5 8.2 3.6 15.2 5.2 32.0 6.2 3.4 4.1 2.5 12.1 1.7 8.4 4.5 12.4 3.7 2.5 26.5 13.4 4.5 2.3 2.7 2.5 17.0 18.6 4.4 3.1 18.1 11.0 32.3 39.5 22.1 14.0 4.0 22.2 4.9 10.5 3.0 19.5 10.4 4.4 5.9 COQ5 MGC4767 ENSG00000110871 "Coenzyme Q5, methyltransferase" Q5HYK3 12 120503279-120534434 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049487 Approved Uncertain Nucleoli,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli Mitochondria "HPA049487: AB_2680789" "unprognostic (1.46e-1)" "unprognostic (1.99e-2)" "unprognostic (1.32e-1)" "unprognostic (6.30e-3)" "unprognostic (2.00e-1)" "unprognostic (1.66e-1)" "unprognostic (1.88e-1)" "unprognostic (1.60e-1)" "unprognostic (2.01e-2)" "unprognostic (6.20e-2)" "unprognostic (1.62e-1)" "unprognostic (8.37e-2)" "unprognostic (3.79e-2)" "unprognostic (2.02e-1)" "unprognostic (7.73e-2)" "unprognostic (2.00e-2)" "unprognostic (3.88e-2)" 22.7 29.9 22.3 15.9 25.3 11.3 24.1 24.5 29.0 19.7 26.7 24.7 23.4 17.9 23.0 20.4 22.2 14.4 40.7 22.1 23.4 38.9 60.7 15.4 23.3 24.9 24.2 20.5 20.6 21.6 18.1 23.3 24.8 18.9 24.7 26.3 22.4 15.8 98.5 17.6 20.0 18.2 22.8 21.1 19.3 24.7 24.3 22.3 25.7 69.2 23.4 17.2 17.6 29.5 35.7 56.1 49.2 14.2 63.5 48.5 33.7 42.3 27.6 42.5 26.9 22.5 29.2 35.6 48.8 44.7 29.9 37.7 44.2 47.2 43.3 45.4 26.3 47.4 35.0 37.8 51.8 52.2 28.7 46.8 50.2 40.0 46.1 66.0 38.0 67.5 47.4 25.3 49.7 46.9 30.3 60.0 43.2 25.4 43.2 55.9 49.8 52.0 55.2 26.7 37.0 29.8 30.7 15.5 58.3 51.2 77.8 42.6 37.9 29.1 33.4 21.8 28.5 53.9 48.5 40.5 33.3 48.9 35.8 28.6 44.3 32.3 39.7 44.9 39.0 45.6 42.4 43.2 61.0 52.7 56.8 45.5 9.3 60.6 43.5 40.3 57.2 54.4 22.3 25.3 24.5 29.0 22.1 23.4 24.9 24.2 24.8 22.8 24.3 29.5 14.4 12.8 12.8 7.2 15.5 7.8 11.5 33.5 10.8 12.6 17.5 15.2 30.5 18.6 18.1 14.7 14.6 73.0 12.9 16.1 46.9 32.3 59.8 17.8 12.1 15.4 15.0 17.5 5.7 20.0 45.6 16.5 11.7 11.3 17.2 24.0 15.4 42.4 46.3 5.0 7.8 17.0 22.4 12.8 10.1 23.1 16.4 13.6 23.2 3.7 29.0 18.0 23.7 6.6 17.5 11.0 23.9 18.8 11.0 11.2 35.8 66.7 22.4 15.6 6.6 16.3 14.4 34.7 14.8 14.3 8.9 58.3 15.0 32.8 28.1 10.9 COX18 FLJ38991 ENSG00000163626 "Cytochrome c oxidase assembly factor COX18" Q8N8Q8 4 73052362-73069755 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046772, HPA049489" Approved NA NA "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 52: Non-specific - Transcription" "HPA046772: AB_2679799, HPA049489: AB_2680791" "unprognostic (3.32e-3)" "unprognostic (2.01e-1)" "prognostic favorable (6.31e-4)" "unprognostic (9.01e-3)" "unprognostic (2.43e-1)" "unprognostic (2.17e-1)" "unprognostic (3.81e-2)" "unprognostic (6.97e-2)" "unprognostic (2.92e-1)" "unprognostic (5.29e-3)" "unprognostic (1.58e-3)" "unprognostic (2.85e-2)" "prognostic favorable (8.22e-7)" "unprognostic (1.28e-2)" "unprognostic (2.94e-1)" "unprognostic (5.80e-2)" "unprognostic (1.22e-3)" 1.5 3.9 0.7 0.4 0.8 0.5 1.4 1.3 1.0 1.3 1.1 1.6 0.6 1.5 0.9 1.4 1.2 0.4 2.7 0.8 0.9 1.7 2.4 1.2 0.7 0.4 0.6 1.5 2.0 0.7 1.3 0.6 0.5 0.9 0.6 1.3 1.9 0.6 2.7 1.3 1.4 0.4 0.3 1.3 1.7 1.3 1.0 0.4 1.1 1.2 0.5 1.2 1.2 0.7 0.6 1.0 1.0 1.0 0.9 0.9 0.8 1.0 0.9 0.4 0.5 0.8 1.1 1.8 0.7 0.6 0.7 0.6 1.0 0.7 0.4 1.4 0.7 0.9 1.3 1.3 0.7 1.5 1.2 1.1 0.7 0.4 0.8 1.1 0.8 1.6 1.4 1.7 0.8 0.5 1.8 1.0 1.5 1.1 1.1 1.0 1.6 2.6 0.8 0.6 1.5 1.0 1.1 0.9 0.4 0.8 0.8 0.8 1.1 1.0 0.8 1.3 0.5 1.7 0.8 1.1 1.2 1.1 0.8 0.1 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.3 0.2 0.2 0.3 0.3 0.1 0.2 0.2 0.3 0.1 0.1 0.7 0.8 1.3 1.0 0.8 0.9 0.4 0.6 0.5 0.3 1.0 0.7 5.6 3.2 6.3 7.2 10.1 2.5 3.7 4.5 1.2 11.7 7.1 4.2 13.9 5.7 7.3 9.2 22.9 8.0 9.0 5.5 13.7 6.5 4.0 6.7 8.4 6.7 5.4 7.8 10.5 8.0 8.3 7.0 5.6 7.1 0.0 17.4 11.4 16.7 8.8 20.2 10.6 7.7 4.1 13.9 3.0 2.0 9.0 8.4 5.4 6.5 12.5 6.6 11.3 10.1 13.4 9.3 5.2 9.4 18.1 6.6 6.6 13.0 8.1 14.3 13.1 7.5 6.0 10.2 7.3 5.5 1.4 3.0 8.6 12.7 9.6 3.4 CP ENSG00000047457 Ceruloplasmin P00450 3 149162410-149221829 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Copper transport, Ion transport, Transport" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "liver: 1871.4" "Cell type enhanced" "Detected in many" "Club cells: 558.1;Glandular and luminal cells: 406.0;Hepatocytes: 1687.2;Muller glia cells: 720.5;Respiratory ciliated cells: 318.4" "Cancer enhanced" "Detected in many" "liver cancer: 98.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "EFO-21: 318.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001834, CAB008591" Supported "Secreted to blood" NA NA 160000000000 440000000000 "Cluster 62: Liver - Hemostasis" "Cluster 38: EFO-21 - Unknown function" "Cluster 15: Hepatocytes - Hemostasis" "CAB008591: AB_1613734, HPA001834: AB_1078502" "unprognostic (3.58e-1)" "unprognostic (4.24e-1)" "unprognostic (9.61e-2)" "unprognostic (1.80e-2)" "unprognostic (4.14e-2)" "unprognostic (1.02e-2)" "unprognostic (1.06e-1)" "unprognostic (2.97e-2)" "unprognostic (2.07e-1)" "unprognostic (8.75e-2)" "unprognostic (6.03e-2)" "unprognostic (1.70e-1)" "prognostic unfavorable (1.14e-7)" "unprognostic (2.68e-2)" "unprognostic (1.59e-1)" "unprognostic (2.00e-1)" "unprognostic (2.70e-1)" 13.0 2.3 17.9 2.2 18.1 0.9 20.8 18.7 29.8 70.2 129.2 13.0 9.8 14.8 0.0 5.6 8.3 1.1 39.2 17.5 33.0 9.5 1871.4 13.4 18.9 28.1 20.3 0.8 6.5 3.9 28.6 3.4 24.9 7.9 16.4 246.5 39.9 0.9 2.6 13.0 20.8 2.4 19.2 23.1 3.0 1.5 20.1 0.5 16.1 8.3 20.0 23.9 2.3 29.0 0.2 18.8 15.6 0.0 3.3 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.1 318.8 0.0 29.4 0.1 0.2 0.0 0.0 0.2 0.2 0.0 0.4 32.7 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.2 2.5 5.4 0.0 0.0 0.0 0.4 6.7 16.2 0.0 0.2 0.3 1.0 0.1 0.4 0.0 0.4 0.0 0.2 1.7 0.2 0.2 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 17.9 18.1 18.7 29.8 17.5 33.0 28.1 20.3 24.9 19.2 20.1 29.0 2.3 19.2 76.6 3.3 10.6 3.3 8.3 28.6 0.6 6.9 14.0 0.6 0.6 65.8 558.1 9.2 6.2 0.1 0.3 0.1 0.0 83.4 0.9 190.5 51.0 12.6 0.0 34.7 1.5 21.4 0.2 16.3 0.0 406.0 2.5 0.1 34.6 1687.2 0.6 5.0 1.4 0.2 8.2 44.6 6.9 1.2 0.3 4.0 0.0 6.5 1.6 720.5 1.0 0.5 2.0 69.3 0.0 0.4 0.3 19.5 0.0 0.3 318.4 24.8 0.0 0.8 15.3 0.0 0.1 0.8 2.6 0.3 4.9 0.1 0.1 79.0 CPEB1 "CPEB, FLJ13203" ENSG00000214575 "Cytoplasmic polyadenylation element binding protein 1" Q9BZB8 15 82543201-82648861 "Predicted intracellular proteins" "mRNA processing, Translation regulation" "Activator, Repressor, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.6;testis: 32.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 70.0;Inhibitory neurons: 44.3;Oligodendrocytes: 196.5;Spermatocytes: 34.1;Spermatogonia: 62.3" "Cancer enriched" "Detected in some" 6 "testis cancer: 14.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SK-MEL-30: 37.9;U-2197: 106.0;U-87 MG: 39.1" HPA040396 Supported Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA040396: AB_2676960" "unprognostic (3.97e-2)" "unprognostic (1.01e-1)" "unprognostic (1.44e-2)" "unprognostic (1.77e-3)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "unprognostic (3.90e-2)" "unprognostic (2.07e-2)" "unprognostic (1.35e-2)" "unprognostic (7.51e-3)" "unprognostic (1.97e-3)" "unprognostic (9.50e-3)" "unprognostic (8.17e-2)" "unprognostic (2.05e-2)" "unprognostic (5.37e-4)" 2.8 5.0 10.4 1.3 18.6 0.2 2.5 20.3 18.6 9.3 4.5 6.8 1.2 4.2 7.9 3.6 8.3 4.0 2.9 12.7 17.0 1.2 0.2 1.6 0.5 21.3 21.7 14.3 1.3 0.8 21.8 0.3 24.0 2.3 2.4 4.5 1.5 3.7 2.4 1.9 2.5 3.4 15.0 0.6 2.5 32.4 20.4 0.4 2.3 10.5 0.5 7.7 6.1 33.6 0.1 3.6 0.3 0.4 2.6 0.2 0.1 2.8 0.3 1.8 1.4 0.2 0.1 0.0 6.3 1.1 19.5 0.1 5.1 0.0 0.4 0.0 4.2 0.1 0.1 0.1 1.8 0.1 2.3 1.4 0.0 3.5 0.0 0.2 0.0 7.6 8.9 0.2 1.3 0.2 0.6 0.1 8.2 0.1 1.0 0.0 0.2 0.1 0.0 0.1 10.5 2.4 9.2 0.5 37.9 11.2 0.1 1.1 0.1 18.9 7.5 106.0 6.0 5.3 14.3 1.4 39.1 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.5 0.0 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.1 10.4 18.6 20.3 18.6 12.7 17.0 21.3 21.7 24.0 15.0 20.4 33.6 0.3 0.0 0.0 19.6 0.1 0.8 0.3 0.0 0.0 11.5 0.6 0.3 1.9 0.0 0.0 0.0 10.4 0.0 0.1 0.1 0.0 0.1 12.6 0.5 1.4 0.2 0.0 0.0 70.0 0.0 0.0 5.9 0.5 0.1 1.3 0.3 0.4 0.0 0.3 11.8 44.3 0.0 0.0 0.0 0.8 20.0 4.1 0.4 5.4 10.3 0.1 5.2 0.0 10.1 196.5 0.1 0.0 2.2 0.2 0.5 0.0 0.4 2.2 4.3 6.6 1.9 1.8 34.1 62.3 0.0 0.6 0.1 0.4 0.0 0.0 0.1 CPN1 ENSG00000120054 "Carboxypeptidase N subunit 1" P15169 10 100042193-100081869 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "liver: 81.6" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 37.2" "Group enriched" "Detected in some" 12 "liver cancer: 26.6;melanoma: 7.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 17 "SK-MEL-30: 141.8" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Secreted to blood" NA NA 13000000000 "Cluster 62: Liver - Hemostasis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (2.97e-2)" "unprognostic (2.23e-2)" "unprognostic (3.93e-2)" "unprognostic (1.64e-1)" "unprognostic (6.75e-2)" "unprognostic (2.93e-2)" "unprognostic (5.26e-2)" "unprognostic (2.63e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 81.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 141.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 37.2 0.0 0.0 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 7.6 4.4 0.0 0.0 0.1 0.1 0.0 0.2 0.0 CPN2 ACBP ENSG00000178772 "Carboxypeptidase N subunit 2" P22792 3 194339768-194351328 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "liver: 218.6" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 171.8" "Cancer enriched" "Detected in some" 32 "liver cancer: 72.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 29 "Hep G2: 61.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA004732 Uncertain "Secreted to blood" NA NA 25000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA004732: AB_1078561" "unprognostic (4.27e-2)" "unprognostic (3.04e-1)" "unprognostic (1.42e-1)" "unprognostic (4.12e-2)" "prognostic favorable (2.05e-4)" "unprognostic (1.27e-1)" "unprognostic (8.65e-2)" "unprognostic (8.56e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (2.91e-2)" "unprognostic (2.40e-1)" "unprognostic (6.90e-5)" "unprognostic (8.42e-2)" 0.4 3.0 0.7 0.4 0.6 1.5 0.2 0.6 1.1 0.2 0.0 0.2 0.0 0.4 0.4 0.1 0.2 0.4 1.0 0.7 0.8 14.7 218.6 0.2 0.3 0.2 0.2 0.3 0.1 0.1 0.0 0.4 0.2 0.2 0.2 1.1 0.2 0.1 0.1 0.6 0.2 0.2 0.0 1.2 0.4 0.7 0.4 0.1 0.3 0.0 0.2 0.1 0.0 1.1 0.2 0.1 0.3 0.3 0.1 0.8 0.2 0.3 0.1 0.0 0.0 0.4 0.2 0.2 0.3 0.8 0.4 0.5 0.1 0.0 0.2 0.1 0.2 0.3 0.6 61.8 0.0 0.3 0.1 0.1 0.0 0.2 0.1 0.3 0.0 0.3 0.5 0.6 0.0 0.3 0.2 0.3 0.3 0.1 0.1 0.1 0.5 0.0 0.1 0.4 0.3 0.2 0.3 0.2 0.4 0.3 0.2 1.4 1.6 0.2 2.1 0.2 0.1 0.2 0.2 0.1 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.6 1.1 0.7 0.8 0.2 0.2 0.2 0.0 0.4 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.9 171.8 0.2 0.0 0.3 0.0 0.0 2.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 CPNE3 ENSG00000085719 "Copine 3" O75131 8 86514435-86561498 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 249.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029552 Uncertain Supported Nucleoplasm,Cytosol NA NA 71000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "HPA029552: AB_10600703" "unprognostic (5.63e-3)" "unprognostic (1.47e-1)" "unprognostic (2.95e-2)" "unprognostic (4.22e-3)" "unprognostic (9.92e-2)" "unprognostic (6.58e-2)" "unprognostic (8.40e-2)" "unprognostic (4.76e-2)" "unprognostic (3.50e-1)" "unprognostic (1.19e-1)" "unprognostic (8.64e-3)" "unprognostic (2.77e-1)" "prognostic favorable (5.07e-4)" "unprognostic (1.15e-1)" "unprognostic (4.33e-1)" "unprognostic (1.65e-3)" "unprognostic (1.13e-2)" 35.4 29.3 14.6 22.4 17.4 76.6 42.3 23.0 15.0 40.7 24.3 35.0 32.1 33.2 21.4 73.6 32.0 30.1 52.4 15.5 19.2 51.5 46.2 33.8 39.5 15.3 17.6 39.2 29.7 52.1 11.8 25.5 17.3 41.2 34.2 18.2 37.1 29.9 17.5 36.3 30.8 31.7 16.4 28.4 30.1 8.3 16.2 38.5 60.9 26.4 46.5 34.9 25.5 21.8 135.1 46.8 30.9 40.9 116.9 92.1 24.6 63.3 93.3 51.9 58.2 30.4 44.5 36.7 40.6 77.6 31.6 101.2 68.7 67.5 92.5 39.5 52.1 6.0 27.2 34.7 41.0 2.3 1.5 63.0 71.2 57.6 76.0 83.1 64.6 17.6 33.2 68.4 65.0 51.6 65.9 1.8 10.5 110.6 64.4 30.7 28.9 174.4 67.4 92.2 66.2 51.5 55.4 249.3 39.6 35.7 95.0 10.3 69.3 44.5 44.1 61.3 49.4 47.0 63.3 9.9 66.0 12.6 42.9 28.6 32.6 54.3 33.2 38.1 26.2 26.4 27.5 23.8 63.1 26.9 23.8 26.1 46.5 27.6 52.5 62.2 20.9 32.0 14.6 17.4 23.0 15.0 15.5 19.2 15.3 17.6 17.3 16.4 16.2 21.8 84.1 137.8 103.9 23.2 52.0 81.8 110.6 111.8 96.2 16.2 80.2 73.9 120.2 75.8 89.3 69.9 14.6 73.0 85.4 49.4 99.7 77.9 1.6 66.9 73.5 66.3 50.2 28.4 37.0 83.7 55.1 92.6 48.9 83.5 8.2 44.7 66.4 103.9 50.4 45.4 39.9 55.3 81.4 71.0 93.8 4.5 85.7 64.0 53.4 13.1 75.0 75.6 36.0 58.3 24.5 59.3 51.7 87.6 49.4 112.5 53.3 126.1 78.8 17.4 59.2 102.1 77.4 3.2 8.8 183.2 91.1 78.0 55.2 71.4 75.1 91.8 CPNE6 ENSG00000100884 "Copine 6" O95741 14 24070837-24078100 "Plasma proteins, Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 54.3;retina: 16.4" "Cell type enhanced" "Detected in some" "Astrocytes: 15.3;Bipolar cells: 26.3;Horizontal cells: 32.0;Inhibitory neurons: 11.4;Late spermatids: 18.1" "Cancer enhanced" "Detected in single" "glioma: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/84: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031636, HPA076665" Enhanced NA NA "Cluster 65: Brain - Ion transport" "Cluster 16: U-266 - Nucleosome" "Cluster 62: Horizontal cells - Visual perception" "HPA031636: AB_10601203, HPA076665: " "unprognostic (1.02e-2)" "unprognostic (3.26e-4)" "unprognostic (1.64e-1)" "unprognostic (5.66e-5)" "unprognostic (3.51e-3)" "unprognostic (2.53e-2)" "unprognostic (2.49e-2)" "unprognostic (1.09e-3)" "unprognostic (1.71e-1)" "unprognostic (1.67e-1)" "unprognostic (2.30e-2)" "unprognostic (3.65e-2)" "unprognostic (1.32e-1)" "unprognostic (1.01e-2)" "unprognostic (5.79e-2)" "unprognostic (4.50e-2)" "unprognostic (2.71e-1)" 0.2 0.2 42.1 0.2 37.7 0.2 0.0 20.0 41.1 0.2 12.2 1.5 2.5 0.2 0.3 1.7 0.3 0.0 0.2 54.3 24.9 7.0 2.1 0.1 0.0 31.4 23.2 0.1 0.0 0.0 8.0 0.0 32.7 2.8 0.5 16.4 0.0 12.3 0.1 0.4 3.4 0.3 20.8 0.0 0.4 0.5 31.3 0.1 0.2 0.1 0.0 0.7 0.4 26.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.1 37.7 20.0 41.1 54.3 24.9 31.4 23.2 32.7 20.8 31.3 26.0 0.0 0.0 0.0 15.3 0.0 0.1 0.0 0.0 0.0 26.3 0.0 0.0 1.7 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.1 0.0 0.0 6.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.0 11.4 0.2 0.0 0.0 0.0 18.1 0.6 0.0 0.0 1.0 0.0 1.4 0.0 1.5 0.8 0.0 0.0 0.0 0.0 0.3 6.5 2.4 0.0 3.8 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 CPT1C "CATL1, CPT1P, CPTIC, FLJ23809" ENSG00000169169 "Carnitine palmitoyltransferase 1C" Q8TCG5 19 49690898-49713731 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.2;pituitary gland: 28.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 43.4;Excitatory neurons: 34.0;Horizontal cells: 32.0;Inhibitory neurons: 28.1;Late spermatids: 29.7;Oligodendrocyte precursor cells: 21.1" "Cancer enriched" "Detected in many" 5 "glioma: 9.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 40.2;AN3-CA: 33.2;SCLC-21H: 27.4;SH-SY5Y: 70.1;U-87 MG: 29.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014529, HPA063621" Approved Approved Centrosome NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Centrosome "HPA014529: AB_1847206, HPA063621: AB_2732706" "unprognostic (1.09e-1)" "unprognostic (6.25e-2)" "unprognostic (1.03e-2)" "unprognostic (5.18e-3)" "unprognostic (1.73e-1)" "unprognostic (1.46e-3)" "unprognostic (1.39e-1)" "unprognostic (2.54e-1)" "unprognostic (1.06e-1)" "unprognostic (2.49e-1)" "prognostic favorable (1.84e-4)" "unprognostic (4.36e-1)" "unprognostic (1.92e-10)" "unprognostic (9.44e-4)" "unprognostic (3.35e-2)" "unprognostic (3.91e-1)" "unprognostic (4.72e-3)" 3.4 5.3 14.0 1.6 14.8 0.0 2.1 8.5 19.1 6.5 18.8 2.6 1.3 8.1 2.3 1.0 4.9 4.4 3.8 19.2 15.6 1.7 0.8 2.1 1.3 10.1 9.2 5.1 1.4 1.4 28.4 0.7 10.3 3.4 0.6 12.4 1.0 2.5 0.7 1.0 1.8 4.6 4.9 4.9 1.5 3.5 12.9 0.2 2.4 0.2 0.6 2.7 3.7 14.4 0.0 0.0 40.2 33.2 14.0 11.0 0.0 12.6 25.2 16.2 22.4 0.7 0.0 0.8 0.0 12.7 2.0 3.0 0.0 0.0 8.5 0.6 0.1 0.0 0.1 0.0 22.7 0.0 0.0 12.7 0.0 13.3 0.1 4.3 22.2 0.1 0.1 0.0 0.9 0.7 0.2 0.0 1.8 2.7 8.8 0.0 0.0 0.0 0.9 0.0 27.4 70.1 0.1 0.1 0.0 0.6 0.1 0.1 18.3 1.0 0.2 7.7 6.7 0.2 3.2 0.4 29.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.0 14.8 8.5 19.1 19.2 15.6 10.1 9.2 10.3 4.9 12.9 14.4 3.8 0.0 0.0 7.5 0.4 2.2 3.1 0.5 3.4 43.4 0.9 1.3 1.4 1.5 0.0 0.0 16.7 1.1 0.3 0.1 0.0 0.0 8.9 0.5 14.1 7.4 0.0 0.0 34.0 0.0 4.4 6.0 0.0 1.2 0.0 1.9 5.0 0.1 0.3 32.0 28.1 0.1 0.0 0.9 1.2 29.7 3.4 0.8 0.0 7.5 0.0 18.3 0.0 21.1 14.9 0.3 0.0 13.2 1.4 2.1 0.0 0.0 0.0 19.1 0.0 5.8 6.3 3.1 7.0 1.0 1.8 1.1 0.7 4.4 0.2 1.6 CPVL ENSG00000106066 "Carboxypeptidase vitellogenic like" Q9H3G5 7 28995235-29195451 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 219.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 306.1;Kupffer cells: 290.3;Langerhans cells: 531.0;Macrophages: 266.2;monocytes: 176.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 61.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 1136.9;intermediate monocyte: 953.5;myeloid DC: 1319.5" "Group enriched" "Detected in all" 52 "dendritic cells: 1319.5;monocytes: 1136.9" "Cell line enhanced" "Detected in many" "BEWO: 190.8;RPTEC TERT1: 801.1;U-266/84: 205.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB003697, HPA045715, HPA056466" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA 760000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "CAB003697: AB_425990, HPA045715: AB_2679429, HPA056466: AB_2683140" "unprognostic (4.72e-2)" "unprognostic (7.08e-2)" "unprognostic (5.96e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (1.63e-1)" "unprognostic (2.49e-2)" "unprognostic (6.85e-3)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (4.98e-2)" "unprognostic (3.07e-1)" "unprognostic (4.25e-2)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (2.21e-1)" "unprognostic (7.46e-3)" "prognostic unfavorable (4.99e-4)" 44.0 23.5 7.5 66.3 8.7 59.8 24.9 48.9 12.0 28.5 39.6 28.9 32.8 17.1 34.6 25.4 19.8 42.1 79.3 6.8 9.9 96.7 52.9 57.6 92.9 15.2 11.4 18.1 7.9 5.4 10.1 84.9 15.4 17.9 25.7 0.9 5.3 21.3 12.5 19.3 46.5 34.1 11.8 219.0 15.5 34.4 8.8 66.7 128.4 8.3 35.8 50.6 15.8 23.4 1.5 0.2 20.3 0.1 0.1 0.0 190.8 0.0 0.0 1.9 0.4 59.8 0.1 0.0 90.3 0.8 94.4 3.2 51.8 4.2 0.6 0.4 47.9 67.0 1.2 144.5 0.0 0.0 0.3 0.3 5.9 0.7 1.6 0.0 0.6 27.5 45.5 0.1 1.6 0.0 63.4 0.4 31.6 0.1 16.0 0.3 0.0 0.6 801.1 22.8 11.9 9.4 53.6 125.5 101.7 97.0 15.1 49.6 0.0 0.4 0.8 0.5 12.0 17.5 205.5 1.0 0.2 25.0 20.8 19.5 1136.9 5.7 2.6 953.5 3.4 1.8 1.3 1.9 1319.5 1.2 1.2 1.2 23.4 5.8 327.8 34.8 1.5 1142.7 7.5 8.7 48.9 12.0 6.8 9.9 15.2 11.4 15.4 11.8 8.8 23.4 12.3 6.4 16.0 3.3 7.2 12.5 1.3 0.7 5.7 0.0 2.6 3.4 69.1 10.0 2.5 71.7 0.0 138.0 2.1 0.2 35.2 0.5 24.7 3.7 0.3 21.1 1.8 34.1 3.7 15.6 118.3 29.4 1.1 0.6 5.1 2.3 6.8 1.1 306.1 0.0 1.7 1.2 0.0 290.3 531.0 7.6 9.3 266.2 10.6 45.9 176.8 0.2 2.1 2.0 1.3 0.8 0.4 3.0 2.9 0.5 0.4 30.6 1.5 0.4 0.0 31.0 3.0 27.1 92.8 27.2 8.8 118.5 3.3 3.6 1.2 0.9 CPXM2 "CPX2, UNQ676" ENSG00000121898 "Carboxypeptidase X, M14 family member 2" Q8N436 10 123706207-123940267 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 81.3;intestine: 75.4" "Cell type enhanced" "Detected in many" "Early spermatids: 106.8;Late spermatids: 202.5;Oligodendrocytes: 35.6;Peritubular cells: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "BJ: 18.4;fHDF/TERT166: 71.8;SuSa: 28.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048375 Uncertain "Secreted - unknown location" NA NA 62000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA048375: AB_2680377" "unprognostic (1.50e-1)" "unprognostic (3.66e-1)" "unprognostic (2.58e-2)" "unprognostic (4.02e-3)" "unprognostic (2.69e-2)" "unprognostic (6.48e-2)" "unprognostic (1.32e-2)" "unprognostic (1.32e-2)" "unprognostic (1.26e-1)" "unprognostic (8.57e-2)" "unprognostic (4.42e-2)" "unprognostic (2.14e-1)" "prognostic favorable (9.02e-4)" "unprognostic (3.48e-2)" "unprognostic (2.54e-2)" "unprognostic (1.27e-1)" "unprognostic (1.16e-3)" 29.1 6.4 3.9 5.9 7.2 0.0 20.8 9.2 2.6 5.8 81.3 75.4 6.2 10.2 59.8 18.4 16.0 11.2 18.0 3.5 7.2 11.2 2.4 7.0 2.7 16.1 10.7 16.7 5.2 2.5 10.9 1.2 11.6 15.1 7.0 0.5 9.3 12.7 3.8 7.3 14.9 56.9 20.0 16.8 19.9 9.6 10.4 7.8 15.0 7.9 6.6 28.3 9.2 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.4 0.7 1.1 0.1 0.0 0.0 0.0 0.0 71.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 28.0 0.5 0.0 0.0 0.1 0.1 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 7.2 9.2 2.6 3.5 7.2 16.1 10.7 11.6 20.0 10.4 18.3 22.3 0.0 0.6 0.3 0.1 2.2 0.0 0.2 6.2 0.0 0.3 0.4 2.4 0.0 0.0 1.8 0.0 8.3 0.1 0.2 1.9 0.4 106.8 0.2 0.2 26.1 0.0 0.0 5.0 0.2 0.3 23.0 1.1 0.3 0.0 0.1 16.8 0.0 0.3 1.7 0.5 0.7 0.0 0.0 2.7 202.5 10.8 0.6 3.6 0.0 0.0 0.0 0.0 1.0 35.6 0.1 0.1 79.0 1.4 0.0 0.4 0.0 0.0 0.1 0.0 1.6 2.0 1.3 1.9 0.6 2.0 5.1 0.2 0.0 2.7 0.2 CPZ ENSG00000109625 "Carboxypeptidase Z" Q66K79 4 8592660-8619759 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 144.3" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 1.5;Fibroblasts: 8.5;Microglial cells: 2.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 73.6;BJ: 39.7;BJ hTERT+: 51.7;hTERT-RPE1: 30.6;RH-30: 57.6;U-2197: 46.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA078608 Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA078608: " "unprognostic (2.58e-1)" "unprognostic (7.16e-2)" "unprognostic (4.83e-2)" "unprognostic (1.42e-1)" "unprognostic (7.77e-2)" "unprognostic (2.20e-2)" "unprognostic (2.98e-1)" "unprognostic (7.77e-2)" "unprognostic (2.30e-1)" "unprognostic (1.95e-2)" "unprognostic (1.41e-1)" "unprognostic (1.59e-1)" "unprognostic (7.23e-8)" "unprognostic (4.30e-3)" "unprognostic (3.58e-2)" "unprognostic (6.13e-4)" "unprognostic (5.51e-2)" 11.1 1.8 0.3 2.7 1.0 0.0 11.8 0.5 2.9 33.3 2.3 4.6 0.8 14.6 9.1 7.4 19.9 30.7 2.8 0.8 0.4 2.0 1.4 7.1 2.8 0.7 0.5 144.3 3.2 1.8 5.2 42.1 0.8 5.9 1.8 0.1 1.5 24.2 0.2 13.8 2.6 8.4 1.2 1.4 3.3 3.1 0.3 1.5 7.8 0.0 1.0 23.0 25.1 0.9 26.1 0.4 0.0 1.6 5.0 0.5 73.6 39.7 51.7 14.5 5.8 1.7 0.7 0.0 3.7 21.3 0.3 0.0 0.0 0.0 5.4 0.0 2.9 0.0 0.3 0.7 4.4 0.0 0.0 9.2 0.0 0.0 0.0 30.6 0.0 0.0 1.2 0.0 0.9 6.1 0.0 0.1 9.2 0.2 22.0 0.1 57.6 0.0 0.0 1.1 0.1 0.1 1.4 0.5 0.1 8.3 0.3 0.0 0.0 2.0 2.6 46.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.5 2.9 0.8 0.4 0.7 0.5 0.8 1.2 0.3 0.9 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.6 0.0 0.6 8.5 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 CRACD "CRAD, KIAA1211" ENSG00000109265 "Capping protein inhibiting regulator of actin dynamics" Q6ZU35 4 56049073-56328625 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.1;intestine: 19.7;testis: 29.6" "Cell type enriched" "Detected in single" 11 "Cardiomyocytes: 3.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 26.7;SH-SY5Y: 56.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043249, HPA048148" Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA 59000 "Cluster 45: Intestine - Brush border" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "Golgi apparatus" "HPA043249: AB_2678388, HPA048148: AB_2680286" "unprognostic (1.65e-1)" "unprognostic (1.98e-1)" "unprognostic (7.74e-3)" "unprognostic (1.31e-1)" "unprognostic (6.04e-1)" "unprognostic (6.44e-2)" "unprognostic (1.98e-2)" "unprognostic (3.24e-2)" "unprognostic (1.34e-1)" "unprognostic (3.12e-2)" "unprognostic (1.11e-1)" "unprognostic (1.09e-1)" "unprognostic (8.05e-6)" "unprognostic (1.02e-1)" "unprognostic (6.54e-2)" "unprognostic (2.79e-2)" "unprognostic (2.93e-1)" 0.5 2.3 6.6 3.1 9.6 3.9 0.3 8.7 5.6 1.6 0.0 9.5 13.8 3.5 4.2 0.5 2.9 11.3 0.8 5.7 12.8 0.7 0.6 1.0 2.2 18.8 13.3 1.2 1.8 6.3 0.9 0.6 19.1 1.7 8.1 4.1 1.0 3.5 0.0 0.5 19.7 4.4 8.7 2.5 2.7 29.6 11.9 0.6 0.1 0.2 1.9 1.3 1.2 6.2 0.0 2.9 11.2 0.9 0.3 0.0 4.1 0.1 0.4 0.5 1.2 3.4 0.4 10.2 0.3 0.0 9.1 0.0 9.6 0.2 0.3 0.9 5.6 5.7 5.1 0.5 1.6 4.8 0.8 0.4 0.2 0.0 0.1 3.6 5.3 9.1 0.0 9.8 0.1 1.4 7.1 0.4 6.0 8.7 7.2 6.8 6.1 0.2 0.1 2.6 26.7 56.7 1.0 0.3 6.9 9.4 2.4 0.5 2.1 0.3 2.8 0.7 2.6 9.7 6.9 0.1 2.8 0.2 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 9.6 8.7 5.6 5.7 12.8 18.8 13.3 19.1 8.7 11.9 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 CRACDL "C2orf55, KIAA1211L, MGC42367" ENSG00000196872 "CRACD like" Q6NV74 2 98793846-98936259 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.8;epididymis: 31.6" "Cell type enriched" "Detected in some" 9 "Adipocytes: 35.9" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 6 "amygdala: 12.8;basal ganglia: 20.0;cerebral cortex: 30.8;hippocampal formation: 29.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 41.0;HDLM-2: 61.7;Karpas-707: 17.4;MCF7: 16.3;SiHa: 17.3;SK-BR-3: 22.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "amygdala: 19.1;basal ganglia: 45.5;cerebral cortex: 36.9;hippocampal formation: 54.9;olfactory bulb: 15.9" "HPA051082, HPA061678" Enhanced Approved "Microtubules,Cytokinetic bridge,Centrosome" Yes No "Cluster 68: Epididymis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Microtubules, Centrosome" "Cytokinetic bridge" "HPA051082: AB_2681337, HPA061678: AB_2684584" "unprognostic (3.56e-3)" "unprognostic (1.23e-3)" "unprognostic (5.88e-2)" "unprognostic (6.43e-2)" "unprognostic (1.34e-1)" "unprognostic (1.24e-1)" "unprognostic (3.67e-3)" "unprognostic (2.12e-1)" "unprognostic (5.10e-2)" "unprognostic (7.65e-2)" "unprognostic (3.23e-2)" "unprognostic (3.61e-2)" "prognostic favorable (1.13e-5)" "unprognostic (1.22e-1)" "unprognostic (3.34e-1)" "prognostic favorable (1.33e-5)" "unprognostic (2.22e-2)" 5.0 0.9 12.8 1.5 20.0 0.5 5.1 0.0 30.8 5.1 0.0 5.9 8.0 2.1 31.6 11.2 22.6 2.9 3.4 29.7 0.0 4.1 0.3 6.0 0.8 0.0 0.0 0.6 4.7 7.7 6.6 4.5 0.0 2.3 4.6 0.1 11.0 4.6 1.7 6.4 7.5 2.3 0.0 1.3 8.3 6.2 0.0 1.0 5.0 1.5 1.8 2.2 5.5 3.6 8.4 0.4 0.2 3.2 0.0 0.0 41.0 0.0 0.0 0.0 0.0 0.4 4.9 0.0 10.4 0.0 0.2 7.4 0.3 0.4 0.0 61.7 1.2 0.0 0.5 0.5 0.0 0.0 0.1 0.3 2.3 0.1 1.2 0.1 2.5 0.0 0.0 17.4 0.0 16.3 0.2 1.3 0.1 8.3 0.9 0.0 0.0 0.8 3.2 6.5 5.8 0.9 17.3 22.5 0.1 0.0 8.7 1.4 10.7 0.0 1.3 0.0 0.1 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.8 20.0 0.0 30.8 29.7 0.0 0.0 0.0 0.0 0.0 0.0 3.6 35.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 CRACR2B "EFCAB4A, MGC45840" ENSG00000177685 "Calcium release activated channel regulator 2B" Q8N4Y2 11 826144-831991 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 208.7;salivary gland: 223.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 180.4;Breast myoepithelial cells: 116.3;Gastric mucus-secreting cells: 178.9;Hepatic stellate cells: 85.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 3.4;eosinophil: 3.7;memory B-cell: 3.9;naive B-cell: 3.0;NK-cell: 1.7" "Group enriched" "Detected in many" 6 "B-cells: 3.9;granulocytes: 3.7;NK-cells: 1.7" "Cell line enhanced" "Detected in many" "NB-4: 35.2;OE19: 29.6;SK-BR-3: 111.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046217 Approved NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 25: Pancreas - Digestion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "HPA046217: AB_10960833" "unprognostic (8.87e-2)" "unprognostic (4.89e-2)" "prognostic unfavorable (1.81e-5)" "unprognostic (4.47e-3)" "unprognostic (8.20e-3)" "unprognostic (5.27e-3)" "unprognostic (7.31e-2)" "unprognostic (1.90e-2)" "unprognostic (1.63e-1)" "unprognostic (5.61e-3)" "unprognostic (3.49e-3)" "unprognostic (9.25e-3)" "unprognostic (5.28e-2)" "unprognostic (4.29e-3)" "unprognostic (3.03e-1)" "unprognostic (3.65e-1)" "unprognostic (5.15e-3)" 11.9 8.4 1.5 3.3 1.6 13.3 65.8 3.1 2.1 8.3 3.5 43.6 22.4 4.6 1.0 6.7 6.4 6.8 22.4 1.3 1.5 27.0 3.4 14.9 2.4 1.8 1.5 1.3 208.7 6.8 23.3 2.7 1.8 44.9 13.6 1.0 223.6 5.2 4.3 21.9 28.5 1.2 1.1 13.9 81.0 2.4 1.9 0.6 6.4 1.7 2.0 19.6 3.9 1.0 3.6 3.1 0.6 1.5 0.2 0.0 11.5 0.3 0.0 0.1 0.0 3.8 12.0 0.0 4.7 0.0 0.3 3.2 2.1 0.1 0.0 26.2 1.1 13.3 3.1 8.8 0.0 10.9 0.5 0.2 0.5 0.0 0.0 2.2 0.5 1.4 17.3 10.7 0.0 8.0 0.3 35.2 0.9 29.6 0.4 2.4 0.6 22.5 8.7 2.8 2.8 1.5 0.4 111.6 0.0 0.6 17.5 9.0 0.3 1.7 0.6 0.4 0.2 26.3 2.4 3.8 5.5 14.4 0.1 3.4 0.5 3.7 0.1 0.0 0.0 3.9 0.0 0.3 0.0 3.0 0.0 0.0 0.1 1.7 0.3 0.5 0.0 0.2 1.5 1.6 3.1 2.1 1.3 1.5 1.8 1.5 1.8 1.1 1.9 1.0 61.5 6.4 19.8 3.3 16.8 0.0 6.6 0.0 1.8 2.4 180.4 116.3 8.8 22.8 27.2 12.9 0.0 3.8 6.4 18.8 15.6 15.0 2.6 11.6 1.9 34.8 12.2 6.1 0.1 37.1 1.7 2.5 178.9 16.2 1.3 0.6 85.3 2.0 3.5 0.0 0.1 71.9 0.0 5.0 0.0 5.0 2.5 3.8 0.0 3.7 1.2 11.4 0.0 0.0 0.0 25.8 40.5 1.9 24.2 29.6 46.2 4.3 13.1 7.2 13.1 2.4 4.4 2.1 6.5 4.2 0.0 1.8 5.0 1.8 43.6 66.5 CRAMP1 "CRAMP1L, KIAA1426" ENSG00000007545 "Cramped chromatin regulator homolog 1" Q96RY5 16 1612337-1677908 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 28.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041752 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 14: REH - Unknown function" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nucleoli, Cytosol" "HPA041752: AB_10796459" "unprognostic (3.67e-1)" "unprognostic (9.97e-2)" "unprognostic (2.72e-1)" "unprognostic (2.23e-1)" "unprognostic (3.41e-2)" "unprognostic (2.25e-3)" "unprognostic (5.78e-4)" "unprognostic (4.17e-2)" "unprognostic (8.53e-3)" "unprognostic (6.01e-2)" "unprognostic (1.55e-2)" "unprognostic (9.93e-2)" "unprognostic (3.86e-3)" "prognostic favorable (4.93e-4)" "unprognostic (8.57e-2)" "unprognostic (2.29e-1)" "unprognostic (1.33e-2)" 8.0 7.5 7.4 5.6 6.2 13.5 9.0 15.0 6.9 11.1 5.9 10.9 8.1 10.3 6.2 9.0 10.7 5.4 8.3 6.6 4.6 9.4 6.3 9.9 7.6 5.4 5.2 12.5 8.8 5.7 12.4 6.9 5.3 12.0 5.4 9.9 8.4 6.4 7.9 11.0 9.5 6.7 3.2 11.0 9.0 22.9 5.5 10.7 12.7 4.8 6.0 9.6 9.5 7.1 8.5 15.5 15.6 14.5 9.8 9.7 20.3 14.4 7.5 11.5 8.2 11.2 14.0 12.0 12.3 9.9 7.1 15.3 18.7 10.0 10.3 12.7 22.6 14.2 16.0 6.9 7.1 19.0 20.6 8.5 12.6 14.5 12.1 11.2 12.4 17.9 19.6 7.1 6.3 12.4 14.8 10.6 14.9 4.9 8.7 51.2 8.4 16.1 8.2 7.5 16.6 14.0 15.8 11.3 8.3 10.9 9.9 24.3 15.2 11.9 12.8 11.4 13.9 15.0 23.3 24.3 3.7 13.0 10.8 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.4 0.0 0.3 0.0 0.1 7.4 6.2 15.0 6.9 6.6 4.6 5.4 5.2 5.3 3.2 5.5 7.1 10.4 16.0 17.0 0.0 2.7 0.0 5.2 0.0 12.0 8.6 9.3 8.0 0.0 4.3 8.6 9.2 18.8 4.7 12.8 6.1 1.9 5.5 28.0 11.1 14.5 6.8 2.4 4.6 0.0 2.0 3.0 5.4 5.1 15.3 5.1 11.0 6.8 4.3 5.6 3.3 0.0 6.6 0.0 8.2 0.0 9.6 4.4 4.3 0.0 0.0 6.6 6.2 4.1 0.0 0.0 7.1 4.7 6.8 4.7 9.9 6.0 1.6 2.9 17.9 6.6 7.1 5.2 17.3 18.4 9.4 0.0 5.3 5.2 5.6 5.5 5.9 CRAT CAT1 ENSG00000095321 "Carnitine O-acetyltransferase" P43155 9 129094142-129111189 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 227.5;tongue: 201.3" "Cell type enhanced" "Detected in many" "Early spermatids: 181.2;Late spermatids: 521.8;Proximal enterocytes: 136.4;Spermatocytes: 123.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019230, HPA020260, HPA022815" Enhanced Approved "Nucleoplasm,Nuclear membrane" NA NA 8100 "Cluster 39: Non-specific - mRNA processing" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear membrane" "HPA019230: AB_1847212, HPA020260: AB_1847210, HPA022815: AB_2732427" "unprognostic (5.13e-2)" "unprognostic (9.79e-3)" "unprognostic (1.99e-2)" "prognostic favorable (2.36e-4)" "unprognostic (2.19e-1)" "unprognostic (1.14e-1)" "unprognostic (1.15e-2)" "unprognostic (2.18e-1)" "unprognostic (5.11e-2)" "unprognostic (3.24e-2)" "unprognostic (3.13e-3)" "unprognostic (2.03e-1)" "prognostic favorable (0.00e+0)" "unprognostic (1.38e-1)" "unprognostic (9.27e-2)" "unprognostic (1.26e-2)" "unprognostic (7.65e-2)" 36.1 51.3 26.4 5.4 26.6 9.0 29.2 27.0 33.8 31.7 27.5 36.1 33.0 24.8 4.0 37.3 23.1 6.6 68.2 25.1 27.8 46.9 151.2 15.2 3.2 28.8 28.2 23.0 107.1 26.3 12.3 6.6 30.6 42.2 4.2 1.7 32.8 8.9 227.5 29.6 37.2 6.8 26.7 15.2 34.0 146.4 30.2 3.1 21.5 201.3 1.6 31.3 27.5 24.4 0.1 39.3 10.7 21.3 13.4 25.9 17.0 15.0 16.6 18.9 12.0 7.8 14.0 1.5 9.2 25.9 23.2 6.7 2.2 4.9 7.2 23.6 0.3 7.3 19.1 30.4 34.1 0.0 26.1 26.3 0.0 15.7 0.9 15.8 26.2 7.2 3.6 5.7 20.0 9.1 0.5 15.9 2.8 32.0 18.0 16.8 21.8 12.2 18.0 0.6 4.2 12.1 0.0 7.1 4.8 3.4 49.7 5.5 22.6 23.0 1.6 32.1 15.4 25.5 22.6 0.1 28.8 4.2 16.8 1.6 8.4 3.5 3.2 5.5 6.7 1.5 4.4 4.3 8.6 1.3 2.6 3.1 1.1 4.4 5.6 3.9 4.5 6.1 26.4 26.6 27.0 33.8 25.1 27.8 28.8 28.2 30.6 26.7 30.2 24.4 10.5 6.4 3.7 5.5 4.9 3.2 4.7 10.8 0.6 1.5 9.7 8.1 57.8 21.5 8.2 3.7 2.1 45.9 6.0 64.5 17.6 22.6 181.2 3.5 15.7 12.9 15.5 17.4 5.3 22.4 55.6 19.3 16.8 9.9 7.0 12.9 14.6 65.7 20.7 1.7 6.1 23.6 14.2 13.9 10.5 521.8 22.1 12.4 5.4 6.5 8.3 15.5 6.2 3.5 4.0 11.6 47.6 24.5 9.6 9.3 136.4 52.0 2.8 1.3 6.6 10.5 15.7 123.5 8.6 57.4 4.5 50.3 7.6 20.1 29.3 13.8 CREG1 CREG ENSG00000143162 "Cellular repressor of E1A stimulated genes 1" O75629 1 167529117-167553805 "Predicted secreted proteins" "Growth regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 545.7;Kupffer cells: 559.7;monocytes: 322.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 55.4;classical monocyte: 128.4;eosinophil: 75.7;intermediate monocyte: 75.7;myeloid DC: 89.9;neutrophil: 43.7;non-classical monocyte: 72.3" "Group enriched" "Detected in all" 6 "dendritic cells: 89.9;granulocytes: 75.7;monocytes: 128.4" "Cell line enhanced" "Detected in all" "RPMI-8226: 1237.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056390 Approved Vesicles,Microtubules "Secreted to blood" NA NA 520000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Microtubules Vesicles "HPA056390: AB_2683113" "unprognostic (3.25e-1)" "unprognostic (2.00e-1)" "unprognostic (1.91e-1)" "unprognostic (9.65e-3)" "unprognostic (4.64e-2)" "unprognostic (2.35e-2)" "unprognostic (1.55e-1)" "unprognostic (5.02e-2)" "unprognostic (2.07e-3)" "unprognostic (8.54e-2)" "unprognostic (8.65e-2)" "unprognostic (1.21e-1)" "unprognostic (8.24e-3)" "unprognostic (2.99e-1)" "unprognostic (4.63e-2)" "unprognostic (3.78e-3)" "unprognostic (3.16e-1)" 130.5 127.7 37.5 79.0 41.1 125.9 109.7 39.0 45.9 76.8 47.8 77.1 60.3 61.8 109.7 91.7 70.9 128.2 82.2 36.5 40.4 132.1 295.2 99.1 98.9 46.0 39.1 84.2 70.7 75.4 64.8 110.8 44.4 62.9 82.7 80.0 104.5 74.6 71.4 109.8 63.0 77.9 45.7 136.9 61.4 50.1 49.3 35.5 125.8 78.2 63.5 116.3 63.3 61.2 93.5 41.5 21.1 43.5 325.8 89.8 53.0 39.2 17.8 30.7 39.8 67.8 104.4 101.7 112.2 43.6 57.2 143.3 24.3 84.9 20.9 140.3 82.3 41.5 31.1 37.9 111.5 93.6 295.2 94.5 250.5 35.6 38.7 42.7 10.3 35.9 218.5 405.0 42.6 39.2 19.6 95.9 22.8 214.0 63.9 32.5 58.8 1237.2 54.7 64.9 14.0 25.7 98.1 132.8 112.8 70.1 175.5 252.7 19.1 8.0 39.6 126.2 25.9 79.4 168.4 67.7 131.6 96.0 16.3 55.4 128.4 75.7 5.1 75.7 8.0 4.3 7.5 6.5 89.9 2.1 16.6 8.8 43.7 11.0 72.3 6.2 3.9 57.6 37.5 41.1 39.0 45.9 36.5 40.4 46.0 39.1 44.4 45.7 49.3 61.2 44.7 35.3 90.1 5.9 15.3 44.1 49.1 23.1 56.9 17.9 61.7 63.8 55.7 65.8 32.2 55.2 89.6 91.5 18.3 15.6 23.5 36.0 27.6 33.9 19.3 34.2 29.3 124.8 24.7 39.7 41.7 78.4 21.9 64.1 29.9 62.0 48.2 90.3 545.7 15.2 22.1 44.5 14.2 559.7 57.6 27.4 43.5 213.8 24.9 26.2 322.8 30.5 6.2 10.1 14.6 21.0 31.5 28.6 27.8 34.0 46.3 60.6 18.5 31.5 13.1 43.2 40.8 65.5 42.0 86.3 51.1 126.7 17.3 38.9 50.4 44.0 CRIM1 S52 ENSG00000150938 "Cysteine rich transmembrane BMP regulator 1" Q9NZV1 2 36355778-36551135 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 163.8" "Cell type enhanced" "Detected in many" "Adipocytes: 262.9;Hepatic stellate cells: 207.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 466.5;fHDF/TERT166: 462.5;TIME: 651.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000556 Enhanced "Intracellular and membrane" NA NA 170000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA000556: AB_1078567" "unprognostic (2.15e-1)" "unprognostic (5.41e-2)" "unprognostic (6.39e-2)" "unprognostic (3.17e-3)" "unprognostic (3.88e-2)" "unprognostic (3.44e-2)" "unprognostic (1.88e-1)" "unprognostic (6.25e-2)" "unprognostic (2.32e-1)" "unprognostic (4.11e-3)" "unprognostic (8.19e-2)" "unprognostic (1.26e-1)" "prognostic favorable (9.51e-4)" "unprognostic (1.98e-2)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" "unprognostic (6.67e-2)" 88.3 14.6 27.0 18.8 28.1 3.5 58.9 9.4 23.5 26.7 51.4 28.7 14.9 26.6 16.7 30.5 34.4 32.2 34.5 20.3 28.8 70.0 16.0 50.1 14.8 23.5 21.9 36.9 23.5 29.2 7.4 163.8 21.2 25.8 23.2 29.5 31.1 32.6 50.1 27.2 18.2 35.7 22.1 47.1 17.5 12.4 36.1 9.9 33.8 36.5 8.7 38.9 22.2 17.1 100.9 75.4 15.2 17.5 69.1 78.0 125.0 466.5 244.7 255.4 133.4 95.3 34.2 0.2 297.9 462.5 166.1 42.8 11.4 75.2 206.5 1.1 8.7 3.2 96.7 55.5 221.5 2.2 0.6 110.1 55.2 102.4 182.4 238.4 361.9 1.9 4.7 0.7 271.6 9.2 0.2 1.2 11.9 5.2 22.1 5.4 19.6 15.5 159.8 41.1 1.8 0.2 81.5 26.4 3.4 56.2 72.3 2.0 651.1 321.7 116.1 40.4 229.1 25.5 0.5 0.9 94.7 0.4 100.8 1.4 0.1 0.5 0.6 0.0 0.4 0.3 0.2 0.3 0.1 0.2 0.0 0.3 0.2 0.4 0.6 2.1 0.2 0.0 27.0 28.1 9.4 23.5 20.3 28.8 23.5 21.9 21.2 22.1 36.1 17.1 262.9 12.8 43.3 100.2 5.4 66.0 38.5 30.1 43.9 12.0 55.6 72.9 34.4 47.1 26.5 132.4 2.1 111.9 27.1 49.5 3.9 33.5 1.0 37.1 27.7 159.8 31.8 10.7 85.1 2.6 40.6 41.0 10.2 75.9 1.3 27.4 207.1 3.6 27.7 0.0 57.5 37.7 36.7 7.7 32.5 2.0 19.0 8.2 39.2 135.9 7.1 18.5 6.2 65.9 17.2 26.5 30.9 19.9 6.9 75.5 11.5 38.4 28.9 42.5 46.0 18.4 164.6 2.1 9.4 22.0 30.1 173.5 17.1 5.7 33.2 58.3 CRISPLD2 "DKFZP434B044, LCRISP2, LGL1" ENSG00000103196 "Cysteine rich secretory protein LCCL domain containing 2" Q9H0B8 16 84819985-84920768 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 137.3;Fibroblasts: 185.5;Leydig cells: 271.5;Peritubular cells: 265.9;Skeletal myocytes: 146.2;Smooth muscle cells: 341.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 87.2" "Lineage enriched" "Detected in many" 4 "granulocytes: 87.2" "Cell line enhanced" "Detected in many" "ASC diff: 43.7;BEWO: 69.2;HHSteC: 161.4;HSkMC: 68.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 15.6" "HPA030054, HPA030055" Approved Approved Nucleoplasm,Nucleoli "Secreted to blood" No No 219000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Nucleoli" "HPA030054: AB_2732452, HPA030055: AB_10611821" "unprognostic (8.91e-3)" "unprognostic (3.05e-1)" "unprognostic (2.63e-2)" "unprognostic (2.02e-2)" "unprognostic (7.12e-2)" "unprognostic (2.30e-1)" "unprognostic (2.11e-2)" "unprognostic (5.58e-3)" "unprognostic (1.48e-1)" "unprognostic (5.50e-2)" "unprognostic (2.67e-1)" "unprognostic (2.87e-2)" "prognostic unfavorable (1.97e-6)" "unprognostic (7.35e-3)" "unprognostic (3.38e-2)" "unprognostic (2.99e-3)" "unprognostic (5.15e-3)" 113.4 29.0 3.3 46.6 4.9 8.1 64.2 3.9 4.6 112.9 2.6 88.9 10.8 115.7 20.3 39.9 129.0 104.0 36.6 3.7 5.2 40.9 17.1 92.7 7.3 5.9 5.5 80.7 23.5 2.5 19.3 122.7 5.9 98.9 18.1 2.4 18.1 27.7 15.0 36.7 58.5 95.0 4.4 24.9 65.9 21.5 4.3 8.2 47.9 12.2 3.7 119.9 69.8 5.7 0.9 2.2 0.6 6.0 43.7 16.2 69.2 34.5 30.4 27.2 19.1 4.7 2.9 0.1 3.0 30.5 8.0 1.0 0.1 0.1 27.3 0.0 0.2 0.5 0.9 0.1 161.4 0.0 0.3 68.0 0.1 8.0 0.1 9.0 0.2 0.0 0.3 0.3 3.1 1.4 0.3 1.7 2.0 4.6 2.0 0.1 0.3 0.4 0.2 5.5 6.7 0.5 8.1 3.5 0.7 9.4 13.7 0.9 3.8 0.4 1.8 28.3 1.0 0.4 0.1 5.8 0.2 0.5 4.1 14.8 20.2 0.7 0.0 1.2 0.0 0.1 0.2 0.0 1.3 0.0 0.1 0.0 87.2 0.0 0.0 0.1 0.0 4.2 3.3 4.9 3.9 4.6 3.7 5.2 5.9 5.5 5.9 4.4 4.3 5.7 5.9 3.2 2.3 0.7 0.7 46.1 8.6 0.6 9.6 0.5 3.9 7.6 8.6 2.8 1.6 0.0 0.0 7.4 0.8 1.8 0.0 1.4 12.6 7.0 137.3 21.7 3.0 0.0 2.2 0.5 42.4 185.5 27.0 6.3 7.0 11.5 38.6 0.8 4.7 1.7 1.5 4.1 0.0 36.6 39.6 19.6 271.5 14.8 48.0 9.4 41.5 5.1 3.1 54.3 0.6 0.9 0.3 265.9 0.9 17.1 0.2 0.1 0.9 0.7 92.1 146.2 341.2 1.0 1.9 3.7 42.8 9.0 5.4 5.7 2.2 6.5 CRTAC1 "ASPIC1, CEP-68, FLJ10320" ENSG00000095713 "Cartilage acidic protein 1" Q9NQ79 10 97865000-98030828 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.6;fallopian tube: 38.2;lung: 50.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 119.5;Club cells: 36.4;Inhibitory neurons: 63.6;Oligodendrocyte precursor cells: 54.8" "Cancer enhanced" "Detected in many" "melanoma: 43.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 3.0;HMC-1: 2.5;HUVEC TERT2: 7.1;SCLC-21H: 4.7;SK-MEL-30: 7.7;TIME: 9.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008175 Enhanced "Secreted to extracellular matrix" NA NA 550000000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 11: Alveolar cells - Smell perception" "HPA008175: AB_1847254" "unprognostic (2.55e-1)" "unprognostic (6.41e-3)" "unprognostic (4.90e-3)" "prognostic unfavorable (5.01e-6)" "unprognostic (2.54e-1)" "unprognostic (6.96e-3)" "unprognostic (9.30e-2)" "unprognostic (9.13e-2)" "unprognostic (1.02e-2)" "unprognostic (3.01e-1)" "unprognostic (7.66e-2)" "unprognostic (1.69e-1)" "prognostic favorable (1.85e-4)" "unprognostic (6.70e-4)" "unprognostic (1.05e-2)" "unprognostic (3.29e-3)" "prognostic favorable (1.51e-4)" 4.4 0.8 8.7 1.1 23.7 0.0 2.4 10.9 20.1 6.4 0.9 11.5 0.5 1.3 3.8 8.3 38.2 0.3 10.6 9.1 8.1 4.3 0.4 50.0 0.4 45.1 10.2 0.7 1.3 0.8 5.3 0.0 45.6 2.3 0.4 11.3 3.4 33.6 1.1 4.1 2.3 0.8 12.6 0.1 1.8 3.9 18.5 0.2 4.7 1.5 0.3 30.2 4.9 15.5 0.0 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.7 0.0 3.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 4.7 1.1 0.5 0.0 7.7 0.3 0.0 0.0 9.4 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 23.7 10.9 20.1 9.1 8.1 45.1 10.2 45.6 12.6 18.5 15.5 1.9 22.4 119.5 2.9 0.0 1.5 2.7 1.3 5.7 10.1 2.6 2.8 7.1 1.5 36.4 9.2 0.0 0.0 0.1 0.0 0.0 4.6 0.1 0.5 0.1 8.8 1.8 0.0 22.9 0.7 0.0 2.3 0.0 0.6 5.1 0.0 5.7 0.1 0.0 0.0 63.6 0.0 0.0 0.6 0.9 0.6 0.0 0.2 8.8 2.8 0.0 14.1 0.0 54.8 6.2 0.6 0.0 0.4 1.2 1.3 0.0 0.0 0.9 5.3 0.0 3.5 0.3 1.5 1.9 13.1 0.4 0.0 0.4 0.0 0.0 1.7 CRTAM CD355 ENSG00000109943 "Cytotoxic and regulatory T cell molecule" O95727 11 122838500-122872643 "CD markers, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 38.2" "Group enriched" "Detected in some" 4 "dendritic cells: 63.8;Plasma cells: 16.0;T-cells: 54.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 9 "cerebellum: 38.2" "Immune cell enhanced" "Detected in many" "NK-cell: 54.0" "Group enriched" "Detected in many" 4 "NK-cells: 54.0;T-cells: 33.3" "Cell line enriched" "Detected in single" 34 "SCLC-21H: 12.9" "Region enriched" "Detected in some" 44 "cerebellum: 102.6" "Region enriched" "Detected in all" 7 "cerebellum: 25.7" NA NA 6800000 "Cluster 48: NK-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (3.51e-3)" "unprognostic (6.73e-4)" "unprognostic (1.33e-2)" "unprognostic (3.73e-3)" "unprognostic (2.40e-2)" "unprognostic (5.25e-4)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (5.27e-2)" "unprognostic (1.71e-1)" "unprognostic (5.49e-3)" "unprognostic (2.32e-1)" "unprognostic (1.83e-4)" "unprognostic (6.01e-2)" "unprognostic (4.26e-2)" "unprognostic (3.87e-2)" "unprognostic (6.59e-2)" 0.3 0.3 0.3 2.3 0.5 1.8 0.5 38.2 1.4 0.3 0.3 0.5 0.6 0.8 0.5 0.3 0.3 1.5 0.2 0.2 0.4 0.1 1.0 1.8 8.8 1.1 1.4 0.3 0.1 0.1 0.1 0.2 4.2 0.3 0.6 0.0 0.7 0.2 0.1 0.3 1.2 0.2 0.5 3.6 0.8 0.2 0.7 4.9 0.2 0.0 3.5 0.8 0.1 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 4.6 0.6 13.0 5.6 12.9 0.1 1.5 27.0 3.6 0.2 4.3 33.3 1.2 54.0 10.5 0.2 0.1 6.0 0.3 0.5 38.2 1.4 0.2 0.4 1.1 1.4 4.2 0.5 0.7 1.6 1.1 0.0 1.1 0.3 0.8 1.5 0.4 0.1 0.0 0.0 0.4 0.9 0.3 0.0 0.0 0.0 0.0 0.1 63.8 0.1 0.0 0.0 1.2 0.4 0.4 0.3 0.0 0.4 0.5 0.0 0.2 1.6 2.0 0.6 1.3 0.0 0.4 0.2 5.9 0.0 0.7 0.0 0.0 8.8 8.1 1.2 0.0 10.3 3.6 0.0 9.4 0.0 4.1 0.0 0.0 0.0 0.0 0.0 16.0 0.3 0.0 0.1 0.0 0.0 0.0 0.8 0.6 0.3 0.5 0.0 0.9 0.1 54.1 0.0 0.0 0.5 CRYBB1 ENSG00000100122 "Crystallin beta B1" P53674 22 26599278-26618027 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 9.6" "Cell type enriched" "Detected in some" 21 "Hofbauer cells: 82.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 10.3;non-classical monocyte: 7.5" "Lineage enriched" "Detected in many" 7 "monocytes: 10.3" "Group enriched" "Detected in some" 5 "Karpas-707: 43.3;RPMI-8226: 82.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA003448, CAB010058" Supported NA NA 89000 "Cluster 51: Monocytes - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB010058: AB_668166, HPA003448: AB_2732396" "unprognostic (1.31e-1)" "unprognostic (5.56e-3)" "unprognostic (1.39e-2)" "unprognostic (1.44e-2)" "unprognostic (2.29e-1)" "unprognostic (2.18e-1)" "unprognostic (7.89e-3)" "unprognostic (1.51e-1)" "unprognostic (9.51e-2)" "unprognostic (1.05e-1)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "unprognostic (3.88e-4)" "unprognostic (2.62e-2)" "unprognostic (1.23e-2)" "unprognostic (3.22e-1)" "unprognostic (1.76e-2)" 1.3 1.6 1.5 0.9 1.6 0.6 0.6 1.6 2.4 0.6 1.3 0.5 0.4 0.3 9.6 0.4 0.4 1.2 0.4 1.6 1.6 0.2 0.4 0.5 1.2 1.9 1.8 0.2 0.2 0.3 0.5 3.3 2.3 0.2 0.4 0.0 0.4 0.2 0.1 0.1 0.4 0.9 1.9 1.6 0.3 0.3 2.2 0.4 0.2 0.2 0.5 1.1 0.2 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 1.5 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 43.3 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.8 0.0 82.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 4.6 0.0 0.2 0.5 0.0 0.0 0.7 0.2 1.8 0.0 2.2 0.0 0.0 1.0 0.0 0.0 10.3 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.4 0.5 7.5 0.0 0.0 0.6 1.5 1.6 1.6 2.4 1.6 1.6 1.9 1.8 2.3 1.9 2.2 2.1 0.1 0.0 0.0 0.7 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.1 1.3 0.0 0.0 0.9 0.0 0.5 0.2 0.0 0.1 1.3 0.0 0.0 0.2 82.6 0.0 0.2 0.0 0.0 3.5 0.8 0.6 0.0 2.8 1.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.2 0.0 0.0 CRYZ ENSG00000116791 "Crystallin zeta" Q08257 1 74705482-74733408 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Oxidoreductase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 331.0;liver: 282.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 160.0;Distal tubular cells: 226.9;Hepatocytes: 200.6;Proximal tubular cells: 526.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 439.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021921, HPA023290" Approved Supported Cytosol NA NA 6400000 "Cluster 44: Non-specific - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA021921: AB_1847262, HPA023290: AB_1847263" "unprognostic (3.64e-2)" "unprognostic (3.38e-2)" "unprognostic (1.97e-1)" "unprognostic (1.27e-2)" "unprognostic (5.32e-3)" "unprognostic (5.79e-2)" "unprognostic (6.29e-2)" "unprognostic (1.04e-1)" "unprognostic (4.56e-2)" "unprognostic (1.06e-1)" "unprognostic (6.38e-3)" "unprognostic (2.19e-1)" "unprognostic (1.35e-3)" "unprognostic (3.12e-1)" "unprognostic (7.50e-2)" "unprognostic (2.94e-1)" "unprognostic (7.32e-2)" 19.8 34.2 19.2 12.9 19.8 2.2 39.0 19.3 36.0 54.6 54.2 21.4 51.2 40.8 120.6 29.0 50.0 68.9 45.6 21.6 23.3 331.0 282.9 32.4 24.4 21.3 24.9 31.6 64.6 52.9 17.0 16.8 24.4 38.8 22.0 15.3 25.0 56.9 25.1 22.2 44.0 40.1 21.1 19.4 25.1 9.2 24.5 33.9 44.5 23.0 23.8 40.8 21.7 24.9 12.1 112.2 57.6 16.3 64.4 70.2 38.6 36.5 57.1 51.8 57.4 88.9 46.1 64.9 62.0 71.3 92.2 31.0 47.2 46.0 83.6 75.2 19.2 27.0 32.2 179.0 33.8 23.1 52.6 33.1 40.0 82.8 15.1 49.1 43.7 35.9 85.9 22.8 109.2 27.0 42.3 38.6 43.1 93.6 72.6 26.8 53.6 23.7 439.4 36.0 15.9 27.9 8.5 60.1 41.2 64.3 54.0 7.7 21.9 12.3 30.7 38.8 55.7 16.2 33.3 32.1 99.4 9.0 35.6 13.1 9.4 1.9 32.1 15.1 26.2 32.8 31.6 30.3 17.1 26.5 27.4 29.5 1.5 30.3 17.9 14.4 42.3 18.8 19.2 19.8 19.3 36.0 21.6 23.3 21.3 24.9 24.4 21.1 24.5 24.9 6.9 28.9 22.6 4.9 20.4 17.8 28.0 32.4 24.5 4.0 16.8 16.8 32.3 84.4 15.7 160.0 2.1 13.5 8.6 6.6 226.9 53.8 0.2 54.8 7.8 8.0 6.7 8.4 4.5 32.4 18.1 20.7 20.9 27.0 14.5 7.8 12.8 200.6 18.5 0.0 4.4 12.0 8.2 15.7 13.7 2.1 20.8 11.4 10.6 4.7 7.1 7.7 11.3 7.1 9.1 31.2 14.5 20.7 20.5 10.2 79.1 526.6 17.3 2.9 0.0 10.6 16.2 1.7 7.4 19.7 21.2 7.3 16.9 13.8 16.2 17.0 CSF1R "C-FMS, CD115, CSFR, FMS" ENSG00000182578 "Colony stimulating factor 1 receptor" P07333 5 150053291-150113372 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 113.3;placenta: 103.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 103.2;Hofbauer cells: 340.4;Kupffer cells: 291.2;Langerhans cells: 73.4;Macrophages: 196.3;Microglial cells: 134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 444.6;non-classical monocyte: 646.9" "Lineage enriched" "Detected in many" 5 "monocytes: 646.9" "Group enriched" "Detected in some" 4 "BEWO: 123.0;SK-BR-3: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008970, HPA012323" Uncertain Supported "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 1600000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Plasma membrane" "CAB008970: , HPA012323: AB_1848977" "unprognostic (3.82e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-3)" "unprognostic (9.83e-2)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (9.37e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (3.67e-2)" "prognostic unfavorable (4.92e-4)" "unprognostic (1.72e-2)" "unprognostic (4.61e-2)" 51.3 31.0 19.6 75.1 17.1 5.6 19.3 20.2 21.4 21.6 19.3 21.9 24.3 12.1 5.8 21.0 17.2 40.6 16.6 19.8 33.8 7.1 27.5 36.6 54.4 41.4 35.5 12.7 9.9 11.8 5.7 103.3 40.1 9.1 21.5 1.5 10.1 20.8 3.2 13.4 37.3 41.9 36.6 113.3 21.0 7.0 40.6 14.3 6.0 11.8 21.7 42.6 3.8 67.6 4.5 0.2 0.0 0.0 1.9 0.4 123.0 0.2 0.2 0.0 0.0 3.8 0.0 5.9 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.2 1.1 3.0 0.0 6.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 6.1 0.1 0.0 0.0 0.0 1.9 0.6 0.0 0.0 0.2 0.2 0.0 47.8 0.0 1.9 0.0 20.7 0.0 0.8 0.2 0.1 3.3 0.0 0.3 0.1 6.6 2.6 0.0 3.0 138.4 4.0 0.6 444.6 0.6 0.3 0.2 0.4 139.0 0.2 0.3 0.2 21.6 0.2 646.9 11.1 0.5 132.7 19.6 17.1 20.2 21.4 19.8 33.8 41.4 35.5 40.1 36.6 40.6 67.6 2.0 0.0 3.8 0.0 4.3 2.8 0.0 0.0 1.2 0.0 0.5 2.3 3.1 4.3 0.0 0.0 0.0 6.2 2.8 0.0 0.0 0.0 4.8 0.0 0.1 10.5 0.0 2.5 0.4 0.0 103.2 2.2 1.5 0.2 2.5 8.3 2.9 1.5 340.4 0.0 0.5 0.3 0.0 291.2 73.4 5.4 1.8 196.3 3.6 134.9 39.4 0.0 1.0 1.5 0.3 0.1 1.7 0.0 1.0 0.0 0.0 0.1 0.7 0.5 13.1 1.2 2.0 2.2 0.2 0.4 1.3 26.4 1.3 2.2 0.2 0.0 CSGALNACT1 "ChGn, CSGalNAcT-1, FLJ11264" ENSG00000147408 "Chondroitin sulfate N-acetylgalactosaminyltransferase 1" Q8TDX6 8 19404161-19758029 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 86.7" "Cell type enhanced" "Detected in many" "Astrocytes: 494.3;Excitatory neurons: 144.4;Granulosa cells: 214.1;Microglial cells: 224.9;Oligodendrocyte precursor cells: 355.9" "Cancer enhanced" "Detected in all" "prostate cancer: 22.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 62.6" "Group enriched" "Detected in all" 5 "B-cells: 44.5;granulocytes: 24.9;T-cells: 62.6" "Cell line enhanced" "Detected in many" "A549: 57.8;BJ hTERT+: 32.3;GAMG: 22.9;RPTEC TERT1: 39.6;U-2197: 36.8;U-87 MG: 26.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA068462 Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Golgi apparatus" "HPA068462: " "unprognostic (8.90e-2)" "unprognostic (1.57e-2)" "unprognostic (4.66e-2)" "unprognostic (2.58e-1)" "unprognostic (6.03e-2)" "unprognostic (3.17e-3)" "unprognostic (9.78e-2)" "unprognostic (7.76e-2)" "unprognostic (1.20e-1)" "unprognostic (1.60e-2)" "unprognostic (8.22e-2)" "unprognostic (6.82e-2)" "unprognostic (1.22e-2)" "unprognostic (1.89e-1)" "unprognostic (2.38e-2)" "unprognostic (1.46e-3)" "unprognostic (1.02e-2)" 19.4 12.5 20.3 8.8 15.7 11.1 7.4 4.8 18.3 18.0 0.7 4.7 3.5 7.0 5.4 31.2 11.8 16.1 35.8 16.3 11.5 6.0 2.8 11.7 7.6 6.3 11.2 57.0 7.9 11.4 3.0 38.8 7.6 31.8 2.5 2.5 6.8 9.8 5.8 4.8 4.7 12.3 6.7 8.7 6.9 2.8 8.9 11.7 86.7 11.0 8.8 23.4 8.1 10.7 2.1 57.8 0.5 0.0 9.3 2.1 7.9 1.4 32.3 0.3 0.3 3.1 1.0 0.0 0.3 0.0 22.9 0.7 0.0 0.0 0.4 7.5 0.4 0.2 16.2 1.9 4.1 0.0 0.1 0.9 1.6 0.7 0.3 0.4 11.6 0.2 0.0 0.1 0.1 2.6 2.9 0.2 0.3 8.3 1.7 0.3 0.1 0.0 39.6 1.6 0.2 0.3 17.2 6.9 2.4 1.5 0.1 0.4 1.0 1.1 1.3 36.8 0.9 0.3 0.0 0.0 26.0 3.4 11.4 0.1 2.9 24.9 5.6 0.1 0.6 44.5 25.7 8.5 2.8 15.9 44.6 11.6 15.6 8.4 0.4 4.2 62.6 11.7 20.3 15.7 4.8 18.3 16.3 11.5 6.3 11.2 7.6 6.7 8.9 10.7 33.3 3.2 1.1 494.3 27.3 4.5 7.4 0.2 0.6 0.3 4.1 0.8 45.8 0.0 0.9 12.9 10.4 1.9 6.2 0.0 1.9 5.7 6.9 7.5 1.2 38.5 3.0 3.2 144.4 1.7 14.6 20.9 2.0 2.0 0.0 214.1 26.7 0.2 15.8 18.5 76.5 0.0 16.2 27.4 6.5 7.4 5.3 14.1 12.4 224.9 3.5 1.0 6.2 355.9 4.6 3.1 0.0 12.0 21.3 21.8 0.0 0.1 1.5 1.0 6.6 2.1 12.0 0.7 0.1 0.5 3.1 8.3 9.6 77.0 0.1 2.8 CTDNEP1 "DULLARD, HSA011916, NET56" ENSG00000175826 "CTD nuclear envelope phosphatase 1" O95476 17 7243591-7252491 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 410.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037439, HPA066466" Uncertain Approved "Lipid droplets" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" "Lipid droplets" "HPA037439: AB_10601264, HPA066466: AB_2732745" "unprognostic (7.11e-2)" "unprognostic (7.78e-2)" "unprognostic (1.33e-2)" "prognostic favorable (6.45e-4)" "unprognostic (3.12e-1)" "unprognostic (2.13e-1)" "unprognostic (4.61e-2)" "unprognostic (1.50e-2)" "unprognostic (2.98e-1)" "unprognostic (9.90e-2)" "prognostic favorable (1.81e-4)" "unprognostic (3.37e-1)" "unprognostic (2.77e-3)" "unprognostic (1.73e-1)" "unprognostic (1.43e-1)" "unprognostic (9.97e-2)" "unprognostic (2.02e-2)" 99.7 94.2 53.0 41.4 52.5 48.8 91.4 49.2 55.1 102.4 51.2 89.8 36.4 97.6 37.1 105.2 88.2 32.1 119.0 49.9 49.0 85.5 69.1 91.6 45.9 55.9 52.7 103.4 98.5 44.4 83.8 41.1 51.2 81.8 46.7 29.7 82.6 33.6 410.0 114.7 93.8 45.0 50.5 115.9 95.4 66.5 55.8 56.2 81.2 179.2 61.8 88.2 87.0 52.8 86.2 123.9 68.4 73.7 105.0 128.0 52.5 62.4 102.8 97.4 83.1 59.6 57.7 80.6 65.6 111.5 68.6 70.5 90.8 95.4 108.6 118.5 74.6 55.2 79.7 104.1 96.5 63.3 100.3 103.4 113.8 111.9 118.3 99.9 105.2 76.2 50.9 56.3 93.3 53.4 77.3 67.0 48.3 75.7 50.9 85.3 61.3 62.6 77.9 44.1 26.3 75.5 49.8 48.9 69.8 67.6 46.3 51.5 61.6 70.9 61.3 57.5 119.4 49.2 46.0 40.6 91.5 85.8 75.1 4.2 6.3 11.0 5.5 6.7 4.4 7.8 5.2 5.9 4.6 7.4 4.0 5.9 8.4 4.1 4.5 9.7 5.7 2.3 53.0 52.5 49.2 55.1 49.9 49.0 55.9 52.7 51.2 50.5 55.8 52.8 48.0 25.6 23.2 12.7 47.1 47.2 42.4 36.1 19.9 44.8 73.9 70.1 13.1 37.1 33.5 40.5 22.9 66.1 68.3 84.5 11.7 63.7 4.8 50.0 59.9 47.2 73.7 18.5 14.7 85.2 129.9 43.5 22.4 68.5 20.3 71.3 44.6 35.6 90.6 30.3 17.0 79.6 22.4 104.4 62.2 7.9 57.8 69.8 28.4 14.0 69.2 47.9 59.8 11.6 21.9 84.5 52.1 47.0 41.3 58.3 62.8 34.8 25.8 35.4 26.3 42.5 51.4 23.7 35.5 32.5 67.1 83.2 41.3 68.3 69.6 61.8 CTF1 "CT-1, CT1" ENSG00000150281 "Cardiotrophin 1" Q16619 16 30896614-30903547 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 16.4;Cardiomyocytes: 11.4;Distal tubular cells: 31.3;Muller glia cells: 21.1;Proximal tubular cells: 14.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 13.6;ASC TERT1: 14.7;fHDF/TERT166: 11.9;HHSteC: 13.0;HSkMC: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025853 Uncertain "Secreted to blood" NA NA 11900 "Cluster 6: Non-specific - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "CAB025853: " "unprognostic (1.31e-1)" "unprognostic (9.01e-2)" "unprognostic (6.81e-3)" "unprognostic (1.06e-3)" "prognostic unfavorable (7.22e-5)" "unprognostic (2.12e-2)" "unprognostic (1.73e-1)" "prognostic favorable (9.87e-4)" "unprognostic (4.47e-2)" "unprognostic (1.09e-1)" "unprognostic (6.75e-2)" "unprognostic (2.76e-2)" "unprognostic (1.76e-3)" "unprognostic (5.07e-3)" "unprognostic (2.06e-1)" "unprognostic (2.16e-2)" "unprognostic (1.79e-1)" 6.4 8.1 4.8 1.3 4.7 1.5 6.7 4.1 5.2 14.7 5.3 13.4 0.8 17.3 4.2 5.3 12.1 3.8 16.0 4.5 4.5 10.2 1.2 7.4 1.3 5.3 5.8 18.4 3.6 10.0 5.2 2.0 4.7 12.2 1.0 2.1 5.7 12.7 14.1 2.7 4.6 7.6 5.5 1.7 7.6 3.4 5.0 2.1 8.5 10.9 1.1 14.0 9.6 5.0 2.0 0.3 2.6 5.7 13.6 14.7 4.5 4.3 8.5 4.4 5.6 2.4 0.4 0.1 8.3 11.9 0.4 1.5 0.0 3.0 4.4 0.1 0.2 0.1 0.2 0.9 13.0 0.2 0.8 13.9 3.8 3.3 8.0 4.9 1.2 0.2 3.7 0.4 7.9 0.3 0.3 0.4 0.8 1.2 0.8 1.6 3.9 0.0 0.7 0.9 0.2 1.4 0.0 0.1 0.0 4.0 6.9 0.3 0.9 4.2 5.2 0.2 0.1 0.1 0.1 0.2 3.3 0.5 0.0 0.6 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.0 0.2 0.2 0.1 0.1 0.4 0.1 0.1 0.3 0.0 0.0 4.8 4.7 4.1 5.2 4.5 4.5 5.3 5.8 4.7 5.5 5.0 5.0 0.8 3.2 6.4 2.6 0.8 0.4 16.4 1.8 2.2 0.3 6.2 7.1 11.4 2.8 1.8 7.3 0.0 0.3 1.2 0.0 31.3 1.0 0.6 7.1 2.9 1.1 0.0 0.4 0.3 0.4 0.2 3.9 0.0 2.4 0.0 3.8 0.0 0.4 0.6 0.0 0.6 0.2 0.0 0.6 0.8 0.7 2.1 1.1 0.0 1.0 0.4 21.1 0.0 1.0 0.4 0.4 0.0 2.6 0.6 2.7 0.2 14.4 2.5 0.9 0.0 4.6 3.0 0.8 0.4 1.9 0.3 0.4 0.7 3.9 0.2 7.4 CTSH "ACC-4, ACC-5, ACC4, ACC5, CPSB" ENSG00000103811 "Cathepsin H" P09668 15 78921058-78949574 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 349.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1569.9;Proximal tubular cells: 523.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 208.5;intermediate monocyte: 137.7;memory B-cell: 83.3;myeloid DC: 183.6;naive B-cell: 56.0;non-classical monocyte: 94.8" "Group enriched" "Detected in all" 5 "B-cells: 83.3;dendritic cells: 183.6;monocytes: 208.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 306.4;HaCaT: 228.2;HDLM-2: 183.0;OE19: 197.4;RT4: 362.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000458, HPA003524" Enhanced Supported "Vesicles,Cytosol,Cytoplasmic bodies" "Intracellular and membrane" NA NA 8700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Vesicles, Cytosol, Cytoplasmic bodies" "CAB000458: , HPA003524: AB_1846075" "unprognostic (6.47e-2)" "unprognostic (4.65e-3)" "unprognostic (1.05e-1)" "prognostic favorable (6.90e-4)" "unprognostic (4.37e-2)" "unprognostic (1.93e-1)" "unprognostic (7.18e-2)" "unprognostic (3.30e-3)" "unprognostic (2.22e-1)" "unprognostic (5.96e-2)" "unprognostic (4.10e-2)" "unprognostic (3.89e-2)" "unprognostic (6.63e-3)" "unprognostic (3.83e-1)" "unprognostic (4.42e-2)" "unprognostic (2.70e-3)" "unprognostic (1.79e-3)" 34.3 36.4 29.4 100.6 30.2 36.9 48.8 29.9 47.1 112.8 31.4 32.5 77.8 46.7 26.8 37.9 57.6 104.6 51.3 29.6 32.9 238.2 89.5 349.6 191.8 30.8 31.4 30.0 75.5 77.6 10.1 25.7 31.5 59.7 27.3 4.7 63.0 70.7 16.3 48.4 56.7 43.1 30.7 51.8 93.9 10.1 32.7 51.8 27.7 37.7 131.3 202.2 30.6 32.4 122.0 10.0 1.2 30.5 5.4 0.5 20.3 8.6 3.0 13.9 7.0 17.6 306.4 34.6 12.6 0.0 13.5 228.2 5.2 52.6 10.1 183.0 0.4 3.0 1.3 38.4 12.1 0.4 7.1 5.6 10.7 0.2 0.0 59.4 1.0 5.9 76.0 0.0 17.9 2.8 32.6 87.8 8.9 197.4 4.9 0.3 0.4 5.9 49.9 362.1 2.6 5.2 41.5 27.8 75.4 10.1 12.5 48.0 16.4 0.2 6.2 0.0 5.3 0.8 92.4 19.5 0.1 89.2 12.3 0.0 208.5 2.0 7.6 137.7 29.7 83.3 20.5 7.4 183.6 56.0 1.8 3.8 8.7 3.2 94.8 22.9 18.3 147.5 29.4 30.2 29.9 47.1 29.6 32.9 30.8 31.4 31.5 30.7 32.7 32.4 169.8 237.2 1569.9 59.1 127.4 24.2 280.7 363.9 30.1 1.3 45.5 41.7 26.2 358.9 258.7 367.8 4.2 19.8 8.1 9.1 84.1 225.0 25.3 67.0 86.0 124.5 9.1 3.0 2.2 142.0 39.6 53.8 106.0 42.8 32.8 2.7 14.3 115.5 256.7 0.0 2.9 18.6 101.7 177.8 259.6 22.6 73.0 350.4 80.0 15.9 360.9 22.6 5.2 1.5 1.1 84.6 16.0 6.0 155.8 112.0 153.0 523.2 261.6 6.6 19.7 4.5 22.3 12.3 56.4 41.6 18.6 23.4 29.4 17.8 40.1 340.4 CTSK "CTSO, CTSO2, PKND, PYCD" ENSG00000143387 "Cathepsin K" P43235 1 150794880-150809577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 420.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 372.4;Langerhans cells: 123.6;Leydig cells: 119.0;Melanocytes: 97.8;Peritubular cells: 149.7;Theca cells: 80.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebral cortex: 18.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8" "Lineage enriched" "Detected in single" 4 "monocytes: 1.8" "Group enriched" "Detected in many" 9 "ASC diff: 2284.0;ASC TERT1: 813.2;BJ hTERT+: 1949.1" "Low region specificity" "Detected in all" HPA050346 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA050346: AB_2681101" "unprognostic (1.48e-1)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (7.61e-3)" "unprognostic (5.08e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (6.60e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.49e-1)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.12e-5)" "unprognostic (6.07e-3)" "unprognostic (2.98e-2)" "unprognostic (5.93e-3)" "unprognostic (6.41e-2)" 224.1 12.5 2.7 33.1 2.8 3.1 227.7 2.9 18.1 420.6 16.4 68.6 13.8 334.0 44.9 46.0 74.0 299.2 35.8 2.7 2.6 12.7 9.0 36.4 42.1 2.7 2.7 78.4 10.6 6.1 14.6 18.9 2.6 34.1 61.8 6.9 53.3 38.0 15.7 219.8 63.8 141.6 2.8 20.2 41.7 15.1 2.7 12.3 34.7 46.3 48.7 210.5 176.2 2.9 0.7 0.3 1.4 0.8 2284.0 813.2 1.0 55.2 1949.1 3.3 8.3 0.3 0.3 0.4 0.6 129.8 0.0 0.6 0.3 0.4 1.2 0.4 0.4 1.4 0.5 0.0 11.0 0.2 1.3 156.5 1.7 50.5 0.7 137.6 4.2 0.6 0.4 1.4 1.5 1.4 0.0 3.0 10.2 1.0 0.0 0.2 0.1 0.1 3.2 0.1 0.6 2.9 0.4 0.0 29.3 3.9 1.0 1.5 1.0 0.7 0.5 0.6 0.6 2.3 1.7 3.6 184.1 0.0 9.9 0.0 1.8 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.4 0.6 2.7 2.8 2.9 18.1 2.7 2.6 2.7 2.7 2.6 2.8 2.7 2.9 17.9 3.2 4.6 2.6 1.1 68.8 0.5 1.6 2.2 12.1 3.7 9.5 2.0 1.5 3.9 3.7 4.2 1.3 2.8 1.5 0.0 1.0 0.9 2.5 59.0 10.2 1.2 0.8 5.0 0.2 2.5 372.4 11.2 3.8 0.0 77.5 14.6 0.5 21.4 3.3 7.7 1.6 8.2 4.6 123.6 4.4 119.0 8.7 97.8 7.5 4.9 2.7 3.1 7.1 2.5 1.4 1.4 149.7 0.8 1.0 1.4 0.1 2.2 7.7 13.1 4.5 33.9 1.4 1.0 2.6 59.1 1.0 5.4 80.9 1.0 0.7 CTSO CTSO1 ENSG00000256043 "Cathepsin O" P43234 4 155921580-155953912 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 37.1;HSkMC: 44.6;Karpas-707: 85.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002041 Approved "Intracellular and membrane" NA NA 25000 "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA002041: AB_1078408" "unprognostic (3.96e-3)" "unprognostic (1.62e-2)" "unprognostic (1.03e-1)" "unprognostic (1.33e-2)" "unprognostic (9.10e-3)" "unprognostic (2.55e-1)" "unprognostic (3.80e-3)" "unprognostic (2.07e-1)" "unprognostic (6.62e-2)" "unprognostic (1.33e-1)" "unprognostic (2.20e-1)" "unprognostic (1.05e-1)" "unprognostic (7.55e-2)" "unprognostic (4.87e-3)" "unprognostic (4.73e-2)" "unprognostic (1.11e-1)" "unprognostic (1.79e-1)" 19.1 31.5 8.0 17.8 8.0 5.0 31.9 6.2 11.8 36.7 7.9 19.6 32.8 37.2 36.1 16.7 36.9 40.7 20.2 7.8 7.6 34.5 98.8 36.8 24.5 7.1 7.5 28.0 19.9 24.5 9.6 41.2 6.9 29.8 23.2 5.2 22.1 32.2 6.7 10.0 34.0 30.7 7.0 39.7 15.5 9.4 7.4 14.1 34.5 17.8 17.9 28.0 15.4 7.6 0.8 0.6 4.1 3.7 17.3 37.1 0.2 1.6 18.3 3.3 5.7 0.4 14.4 0.2 1.2 6.8 1.2 0.1 0.2 0.1 2.6 1.6 0.1 0.4 0.5 0.2 18.1 1.4 0.2 44.6 3.5 2.2 1.8 25.6 3.5 0.7 0.3 85.8 11.7 0.7 1.1 0.4 0.7 0.6 0.7 4.8 0.5 1.0 16.8 7.5 0.5 4.3 2.4 9.3 2.3 2.0 4.2 2.6 3.0 13.3 0.7 0.4 2.3 8.3 0.2 0.2 24.4 0.3 18.6 5.3 0.9 0.6 1.2 0.7 3.0 1.2 1.4 0.8 0.4 1.5 1.6 2.0 0.7 3.0 0.9 1.0 3.3 1.4 8.0 8.0 6.2 11.8 7.8 7.6 7.1 7.5 6.9 7.0 7.4 7.6 29.3 38.5 20.8 15.0 19.9 10.5 13.1 11.3 12.0 10.4 20.1 13.0 5.0 44.3 14.3 25.8 2.1 20.5 19.6 15.6 13.7 24.6 0.4 20.9 34.6 28.2 6.7 8.6 1.7 20.7 7.7 51.5 8.6 27.3 8.8 25.0 43.2 58.1 16.3 5.0 1.7 7.9 8.2 29.2 23.7 1.5 30.4 21.4 30.2 7.5 26.5 17.0 22.6 36.7 5.4 12.7 6.3 25.2 7.0 17.5 21.1 10.7 14.5 1.9 19.7 34.0 24.6 0.3 2.1 5.9 9.1 10.5 14.5 14.3 6.6 9.5 CTSS ENSG00000163131 "Cathepsin S" P25774 1 150730079-150765957 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 137.0;lymphoid tissue: 164.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 698.6;Kupffer cells: 2230.8;Macrophages: 1316.2;monocytes: 2312.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 2483.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 81.6;HMC-1: 187.5;U-698: 387.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000460, HPA002988" Supported Approved Vesicles "Intracellular and membrane" NA NA 23000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "CAB000460: , HPA002988: AB_1078409" "unprognostic (7.81e-2)" "unprognostic (9.04e-2)" "unprognostic (3.23e-2)" "unprognostic (3.93e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-2)" "unprognostic (1.11e-1)" "unprognostic (1.23e-1)" "unprognostic (1.59e-1)" "unprognostic (6.00e-3)" "unprognostic (1.46e-1)" "unprognostic (3.89e-1)" "unprognostic (6.24e-2)" "unprognostic (7.50e-2)" "unprognostic (4.14e-2)" "unprognostic (2.13e-1)" "unprognostic (2.47e-3)" 40.0 16.7 4.0 87.8 4.5 137.0 20.3 4.8 7.1 9.4 8.0 83.6 60.2 7.8 5.7 16.5 17.8 29.1 10.6 3.4 5.5 9.3 40.4 88.4 71.7 11.8 8.0 4.9 11.3 2.3 4.7 23.6 11.2 9.1 59.4 3.4 23.9 7.3 4.1 7.1 64.6 16.3 7.7 164.8 42.6 3.8 10.4 20.1 11.5 9.0 38.5 42.9 10.0 16.1 3.7 10.9 0.2 0.3 1.2 1.4 0.7 0.4 8.6 0.9 1.3 1.2 81.6 44.3 5.7 1.2 15.3 2.1 0.2 0.7 0.5 26.9 0.2 29.0 1.1 0.8 0.2 33.6 187.5 2.6 0.1 6.6 1.5 0.5 6.3 0.6 3.4 45.0 2.4 0.3 0.4 22.5 0.2 0.1 0.3 14.9 4.6 49.8 10.7 8.7 0.3 0.4 1.1 2.3 0.8 0.3 0.4 49.8 9.1 6.2 1.3 0.8 1.2 27.8 2.2 387.3 28.5 35.2 2.3 20.9 2483.4 218.0 41.3 1735.3 51.1 139.5 46.6 50.9 571.0 138.8 45.0 40.8 1022.2 41.8 1655.1 106.8 77.4 2577.6 4.0 4.5 4.8 7.1 3.4 5.5 11.8 8.0 11.2 7.7 10.4 16.1 37.6 109.0 158.7 1.6 255.3 17.0 31.3 72.0 4.6 2.3 21.0 8.9 5.3 74.4 143.4 42.3 12.5 3.7 198.0 549.2 0.0 183.6 6.6 126.9 8.6 44.1 42.4 22.5 10.3 177.0 5.7 34.4 71.9 39.0 106.8 9.5 60.3 30.6 698.6 0.0 9.5 205.7 73.2 2230.8 316.4 3.0 5.3 1316.2 56.9 27.2 2312.9 0.5 137.0 0.5 0.9 200.9 466.5 2.2 121.4 20.6 210.8 4.7 488.9 4.9 19.7 5.6 13.3 0.2 0.5 12.4 15.5 6.2 108.9 66.0 237.8 113.3 CTTN EMS1 ENSG00000085733 Cortactin Q14247 11 70398404-70436584 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Endocytosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.2;neutrophil: 2.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.1" "Cell line enhanced" "Detected in many" "A-431: 450.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011235, HPA057242" Supported Supported "Golgi apparatus,Vesicles,Plasma membrane,Cytosol" NA NA 11000000 "Cluster 34: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "Golgi apparatus, Vesicles" "CAB011235: , HPA057242: AB_2683379" "unprognostic (6.34e-2)" "unprognostic (2.65e-2)" "unprognostic (2.05e-1)" "unprognostic (3.13e-2)" "unprognostic (5.81e-2)" "prognostic unfavorable (2.19e-6)" "prognostic unfavorable (4.45e-4)" "unprognostic (6.10e-2)" "unprognostic (2.39e-1)" "unprognostic (1.10e-1)" "unprognostic (1.25e-3)" "unprognostic (1.20e-1)" "unprognostic (1.50e-2)" "unprognostic (6.97e-2)" "unprognostic (2.79e-1)" "unprognostic (3.72e-3)" "unprognostic (1.94e-1)" 91.7 142.5 28.3 15.6 30.0 4.9 82.9 29.7 32.3 112.3 28.5 84.9 28.4 117.8 18.7 131.6 85.0 35.1 106.9 27.7 28.2 109.6 66.9 74.8 9.0 33.2 30.8 112.9 79.5 18.1 94.1 23.9 30.9 101.6 23.8 8.4 92.9 27.0 65.7 104.4 70.9 31.8 29.5 53.3 92.2 62.0 30.3 8.7 89.5 14.5 12.7 88.1 101.2 32.5 450.2 97.2 32.0 37.2 53.2 81.9 52.5 93.8 92.5 80.7 63.4 129.5 110.3 17.5 90.6 121.1 86.3 97.3 38.6 98.7 58.7 35.5 39.1 1.7 73.6 61.1 113.9 0.4 22.6 116.6 68.0 89.4 50.2 84.4 68.8 0.5 51.3 3.3 80.9 122.9 0.9 6.4 35.0 163.4 58.6 0.2 39.3 14.3 90.5 143.7 26.3 44.9 68.3 93.2 158.0 57.2 75.8 1.9 86.8 70.8 45.3 111.2 63.6 7.4 5.2 1.0 141.1 0.4 98.9 1.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 2.1 0.0 0.1 0.4 0.0 6.8 28.3 30.0 29.7 32.3 27.7 28.2 33.2 30.8 30.9 29.5 30.3 32.5 95.3 44.8 51.8 61.7 4.0 151.9 102.8 85.8 46.1 39.4 81.0 57.9 64.1 80.1 95.4 134.3 18.8 83.8 1.6 224.4 64.6 146.5 12.4 86.4 84.8 89.9 74.4 18.9 93.4 221.5 95.6 89.1 76.0 116.1 6.3 117.7 78.9 44.1 10.4 38.7 65.4 123.8 57.0 8.9 34.1 26.1 103.2 38.6 122.7 28.1 5.9 42.5 0.0 40.2 145.8 260.6 177.8 98.9 3.1 153.5 108.4 164.3 89.4 32.5 59.2 61.0 87.5 32.0 47.0 76.7 174.9 106.3 5.4 91.4 111.9 258.1 CTTNBP2NL DKFZp547A023 ENSG00000143079 "CTTNBP2 N-terminal like" Q9P2B4 1 112396214-112463456 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Langerhans cells: 131.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 8.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 68.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007301 Approved Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" "Nucleoli fibrillar center, Cytosol" "HPA007301: AB_1847693" "unprognostic (1.81e-1)" "unprognostic (1.52e-1)" "prognostic favorable (1.14e-4)" "unprognostic (4.21e-3)" "unprognostic (4.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.48e-2)" "unprognostic (1.22e-1)" "unprognostic (2.61e-2)" "unprognostic (1.30e-1)" "unprognostic (1.29e-3)" "unprognostic (1.05e-1)" "prognostic favorable (8.08e-4)" "unprognostic (1.38e-1)" "unprognostic (1.63e-1)" "unprognostic (9.99e-2)" "unprognostic (5.12e-2)" 14.5 4.8 5.6 10.3 4.6 0.5 11.3 4.4 6.1 11.8 3.1 15.5 7.5 15.2 4.7 19.5 8.4 16.5 6.3 4.4 7.6 9.1 5.6 13.0 6.2 7.3 6.6 9.4 4.6 7.4 3.5 20.2 7.1 8.9 14.8 8.2 7.0 9.2 3.0 15.4 10.5 13.5 5.7 10.6 8.6 5.8 5.9 4.3 8.3 6.9 8.2 15.6 11.8 7.6 21.8 7.9 25.7 12.2 17.0 22.3 8.6 33.6 31.4 21.4 21.1 6.1 10.7 3.4 13.2 25.4 10.5 17.4 16.9 23.2 24.9 7.1 8.1 4.6 13.1 4.9 19.7 1.6 7.8 26.4 14.0 26.5 23.0 24.5 52.7 5.7 4.2 3.0 29.9 6.4 3.0 0.6 16.6 6.1 12.3 5.3 24.0 0.0 32.6 15.9 12.6 13.2 26.0 5.3 13.3 24.5 4.3 1.8 68.5 21.3 24.9 22.0 15.8 0.4 3.1 0.1 22.1 2.0 57.0 0.0 2.6 0.0 0.0 2.1 0.0 0.1 0.0 0.0 8.6 0.3 0.0 0.0 0.1 0.0 0.4 3.7 2.0 0.4 5.6 4.6 4.4 6.1 4.4 7.6 7.3 6.6 7.1 5.7 5.9 7.6 100.4 57.7 22.4 17.6 4.4 38.7 30.2 32.0 24.5 10.2 12.3 9.5 9.7 7.2 41.4 22.0 6.2 17.6 4.6 64.0 3.9 39.1 3.3 29.1 30.7 71.6 8.3 3.6 44.1 21.6 12.8 24.2 14.8 58.5 19.0 17.8 41.7 1.6 13.5 5.0 31.2 27.4 30.5 29.7 131.7 4.0 10.5 40.8 16.0 81.5 30.5 11.0 0.0 30.2 25.1 47.7 52.7 11.3 0.7 25.4 21.7 22.6 17.5 7.9 19.7 20.1 29.2 16.8 16.7 25.0 60.7 25.4 2.7 9.1 24.4 69.3 CUL3 ENSG00000036257 "Cullin 3" Q13618 2 224470150-224585397 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, ER-Golgi transport, Mitosis, Transport, Ubl conjugation pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 224.8" "Cell type enhanced" "Detected in all" "Late spermatids: 309.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002678 Supported NA NA 65000 "Cluster 49: Eosinophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "CAB002678: " "unprognostic (1.22e-2)" "unprognostic (2.35e-1)" "unprognostic (7.05e-2)" "unprognostic (6.29e-2)" "unprognostic (2.82e-1)" "unprognostic (7.03e-2)" "unprognostic (2.70e-2)" "unprognostic (1.13e-1)" "unprognostic (2.53e-3)" "unprognostic (2.65e-2)" "unprognostic (1.01e-2)" "unprognostic (6.16e-2)" "unprognostic (4.86e-3)" "unprognostic (2.16e-2)" "unprognostic (8.74e-3)" "unprognostic (9.61e-2)" "unprognostic (1.87e-2)" 30.6 33.6 26.7 36.3 28.2 62.5 40.6 30.4 34.7 35.3 31.0 38.2 36.1 33.6 41.8 54.2 28.7 32.8 39.0 28.6 30.2 49.4 52.4 31.2 55.5 25.9 26.0 33.2 34.3 56.5 25.2 37.1 26.2 33.4 39.4 46.3 36.1 28.6 112.6 54.1 34.2 33.5 27.0 33.8 35.5 224.8 26.6 48.4 45.7 81.8 75.7 40.6 36.5 31.1 61.7 61.3 87.8 72.6 71.9 62.7 82.7 73.9 74.3 72.6 67.7 72.7 60.2 67.0 44.5 76.1 70.3 53.6 99.8 85.0 112.0 66.5 54.5 95.9 61.3 100.7 87.6 95.1 69.3 62.6 68.9 67.7 74.0 72.2 74.3 61.9 90.2 67.0 96.9 104.5 88.5 91.5 90.4 100.9 38.0 76.5 109.8 50.0 108.5 141.0 79.9 58.6 51.1 73.7 85.7 124.5 58.6 79.3 66.2 77.2 58.5 52.1 74.1 69.2 55.3 115.3 59.9 58.2 83.7 9.4 2.8 7.6 3.5 3.5 4.6 5.3 3.9 5.4 3.0 6.5 4.7 5.2 6.6 8.7 4.2 3.6 7.6 1.7 26.7 28.2 30.4 34.7 28.6 30.2 25.9 26.0 26.2 27.0 26.6 31.1 48.3 51.3 69.6 92.1 73.9 28.3 67.8 25.1 20.5 48.5 40.8 34.7 39.9 30.0 49.7 27.6 29.2 25.7 85.3 46.7 35.2 20.2 211.2 58.9 66.9 35.2 40.9 30.9 86.7 24.9 17.8 35.0 32.6 76.2 38.0 37.1 28.5 39.6 20.7 60.6 93.4 39.2 20.3 43.2 28.3 309.7 27.4 45.2 24.9 95.5 39.4 48.4 28.8 107.1 126.4 34.5 39.3 27.4 58.1 59.8 43.8 43.2 38.7 41.3 52.6 71.8 41.5 116.4 50.7 35.7 32.7 39.5 61.2 40.1 34.0 90.1 CX3CL1 "ABCD-3, C3Xkine, CXC3, CXC3C, NTN, SCYD1" ENSG00000006210 "C-X3-C motif chemokine ligand 1" P78423 16 57372477-57385044 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Chemotaxis, Host-virus interaction, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 104.8" "Cell type enhanced" "Detected in many" "Adipocytes: 115.4;Basal prostatic cells: 50.8;Basal respiratory cells: 51.8;Breast glandular cells: 62.3;Breast myoepithelial cells: 51.1;Club cells: 54.8;Endothelial cells: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "EFO-21: 30.1;HDLM-2: 86.0;Hep G2: 63.8;RPTEC TERT1: 36.5;SK-BR-3: 21.5" "Low region specificity" "Detected in all" "CAB026192, HPA040361" Approved Supported "Plasma membrane" "Secreted to blood" NA NA 1870000 370000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB026192: , HPA040361: AB_10796453" "unprognostic (6.89e-3)" "prognostic favorable (9.46e-4)" "unprognostic (1.52e-2)" "unprognostic (3.20e-2)" "unprognostic (1.73e-1)" "unprognostic (1.82e-1)" "unprognostic (7.12e-2)" "unprognostic (2.08e-3)" "unprognostic (4.49e-2)" "unprognostic (3.70e-1)" "unprognostic (2.59e-2)" "unprognostic (2.06e-2)" "prognostic favorable (8.52e-7)" "unprognostic (5.19e-2)" "unprognostic (2.72e-1)" "unprognostic (1.11e-2)" "unprognostic (9.33e-2)" 68.3 4.8 36.4 5.7 39.5 0.1 104.8 11.9 44.8 17.6 19.8 14.3 5.1 13.7 8.7 14.4 18.2 21.0 43.0 46.9 26.4 41.9 14.9 98.8 8.5 25.1 24.8 8.3 13.1 7.1 11.2 3.9 23.6 42.2 5.4 4.3 70.8 45.3 15.0 27.3 12.8 10.6 21.8 1.4 14.5 5.7 30.5 5.2 29.7 19.2 6.2 33.0 17.3 31.2 0.0 0.8 8.0 6.8 0.3 0.1 2.0 0.1 0.0 0.0 0.1 3.1 0.0 0.0 30.1 0.1 4.3 0.3 0.0 0.1 0.0 86.0 0.4 0.0 0.0 63.8 0.9 0.0 0.1 0.9 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 2.8 0.1 0.0 0.1 1.1 0.2 36.5 0.2 0.2 7.1 0.0 21.5 1.9 5.1 0.1 0.2 0.1 0.3 4.7 0.2 2.1 0.1 0.0 0.0 0.1 0.0 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 36.4 39.5 11.9 44.8 46.9 26.4 25.1 24.8 23.6 21.8 30.5 31.2 115.4 3.2 4.6 3.3 1.2 4.5 50.8 51.8 31.9 9.8 62.3 51.1 8.3 21.5 54.8 3.7 4.2 0.0 0.8 0.5 0.0 35.1 0.4 12.9 3.3 50.7 1.8 0.0 28.1 1.8 0.1 9.0 0.5 27.3 1.3 0.2 6.1 11.7 0.0 5.0 20.5 0.3 20.3 0.8 4.7 0.5 4.7 0.6 0.0 16.9 0.6 0.8 0.0 13.0 3.2 4.3 0.6 27.8 0.0 29.7 0.2 11.8 28.8 2.2 13.1 2.8 15.7 0.1 0.1 10.3 2.6 0.3 0.8 0.3 1.0 32.6 CXCR3 "CD183, CKR-L2, CMKAR3, GPR9, IP10-R, MigR" ENSG00000186810 "C-X-C motif chemokine receptor 3" P49682 X 71615916-71618511 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "Angiogenesis, Apoptosis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.2;intestine: 6.4;lymphoid tissue: 16.3" "Cell type enhanced" "Detected in some" "dendritic cells: 87.6;NK-cells: 15.5;Plasma cells: 36.5;Proximal enterocytes: 17.6;T-cells: 48.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 306.7" "Group enriched" "Detected in many" 5 "dendritic cells: 306.7;NK-cells: 198.9;T-cells: 124.7" "Cell line enriched" "Detected in some" 15 "RPMI-8226: 47.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA045942 Enhanced NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA045942: AB_2679507" "unprognostic (4.84e-3)" "unprognostic (3.05e-3)" "unprognostic (1.61e-1)" "prognostic favorable (3.44e-6)" "unprognostic (3.93e-2)" "prognostic favorable (3.35e-4)" "unprognostic (1.01e-2)" "unprognostic (5.24e-2)" "prognostic favorable (2.90e-4)" "unprognostic (6.32e-2)" "unprognostic (1.34e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (1.67e-6)" "unprognostic (4.67e-2)" "unprognostic (2.18e-1)" "unprognostic (2.91e-2)" "unprognostic (5.76e-2)" 0.6 0.8 0.1 5.9 0.1 7.2 0.5 0.2 0.3 0.5 0.0 1.6 5.4 0.4 0.0 0.6 0.5 1.4 0.4 0.2 0.0 0.5 0.5 3.3 16.3 0.2 0.0 0.4 0.5 0.0 0.1 0.1 0.0 0.4 1.0 0.0 1.8 0.3 0.1 0.6 6.4 0.4 0.0 7.5 2.9 0.3 0.1 3.0 0.9 0.1 5.3 1.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 47.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 3.1 0.0 0.4 0.3 0.2 80.4 0.2 40.9 45.3 90.3 124.7 8.4 9.9 5.5 51.6 1.9 198.9 0.2 306.7 89.4 35.3 0.1 0.1 0.2 0.3 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 13.9 0.3 0.0 0.0 0.0 0.0 0.6 0.5 0.4 0.0 0.0 0.0 0.0 0.0 87.6 3.0 0.0 0.0 0.0 0.2 0.2 0.3 0.0 3.2 0.0 0.2 0.0 0.3 3.1 0.3 1.3 0.0 0.7 0.3 0.3 0.0 0.0 1.8 0.0 0.8 6.1 0.0 0.0 4.0 1.8 0.0 2.1 0.0 15.5 0.0 0.0 0.2 5.3 0.0 36.5 0.0 17.6 0.5 0.0 0.0 0.0 0.8 0.6 0.0 0.1 0.0 0.6 0.1 48.3 1.5 3.1 0.1 CYB5D2 MGC32124 ENSG00000167740 "Cytochrome b5 domain containing 2" Q8WUJ1 17 4143168-4187310 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 130.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 74.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011032, HPA042299" Approved Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum, Plasma membrane" "HPA011032: , HPA042299: AB_10793879" "unprognostic (2.57e-2)" "unprognostic (2.89e-2)" "unprognostic (4.16e-2)" "prognostic favorable (6.19e-4)" "unprognostic (1.88e-2)" "unprognostic (1.75e-2)" "prognostic favorable (4.98e-6)" "unprognostic (1.57e-1)" "unprognostic (2.47e-1)" "unprognostic (9.71e-3)" "prognostic favorable (7.76e-5)" "unprognostic (2.04e-1)" "prognostic favorable (2.03e-10)" "unprognostic (2.01e-3)" "unprognostic (8.73e-2)" "unprognostic (1.82e-1)" "unprognostic (2.97e-1)" 19.0 21.7 17.4 6.1 17.3 4.3 18.2 17.4 20.1 15.9 14.2 10.7 15.2 15.6 28.5 10.9 18.7 16.3 14.0 16.7 19.6 25.5 29.0 9.7 9.3 18.1 17.6 20.8 19.7 30.9 24.1 10.8 17.8 13.5 7.4 9.2 20.0 17.6 16.2 14.4 12.1 8.4 17.6 9.6 16.0 29.3 17.9 10.2 22.7 14.9 7.2 12.9 11.7 18.7 16.2 21.6 11.8 12.7 74.7 22.5 5.2 15.7 31.5 11.0 10.9 6.3 10.3 5.3 13.6 17.4 9.2 22.5 4.9 7.1 4.4 17.9 25.7 5.0 13.5 10.5 13.7 2.1 9.5 28.8 17.0 6.2 11.7 22.3 20.1 11.5 5.1 31.2 8.3 20.6 7.8 3.4 4.3 13.7 11.5 9.2 10.6 12.5 25.1 8.5 9.3 8.1 17.2 9.9 23.5 13.1 25.6 3.2 28.5 15.7 4.0 14.5 8.0 5.8 4.9 3.9 19.9 4.5 6.2 0.6 10.8 13.6 5.9 9.2 6.7 8.1 9.3 7.4 10.5 7.1 8.6 8.0 9.5 5.5 8.7 11.3 11.2 8.2 17.4 17.3 17.4 20.1 16.7 19.6 18.1 17.6 17.8 17.6 17.9 18.7 57.4 12.8 10.3 9.1 17.2 53.7 18.4 36.0 12.5 26.9 35.4 36.7 9.8 45.8 21.8 31.3 58.4 55.7 11.4 18.5 52.8 34.3 28.5 36.6 20.0 34.4 13.8 33.3 7.6 27.0 29.1 23.8 19.4 23.4 11.4 22.3 41.0 32.9 21.4 40.4 10.4 16.0 36.7 24.0 23.8 30.6 28.9 17.3 14.2 4.7 15.4 37.6 15.5 8.5 10.0 26.9 18.9 28.6 17.6 8.3 39.7 55.7 38.5 30.4 0.0 15.2 20.1 130.3 29.2 9.5 42.9 38.6 15.8 39.3 16.6 15.8 CYBB "CGD, GP91-PHOX, NOX2" ENSG00000165168 "Cytochrome b-245 beta chain" P04839 X 37780059-37813461 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 160.9;lymphoid tissue: 158.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 157.2;Kupffer cells: 456.0;Macrophages: 469.3;monocytes: 396.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 276.3;intermediate monocyte: 261.6" "Group enriched" "Detected in many" 4 "dendritic cells: 90.9;granulocytes: 110.5;monocytes: 276.3" "Group enriched" "Detected in some" 5 "Daudi: 52.8;NB-4: 64.2;REH: 54.6;RPMI-8226: 210.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051227 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA051227: AB_2681395" "unprognostic (5.83e-2)" "unprognostic (1.77e-2)" "unprognostic (2.15e-3)" "unprognostic (1.48e-2)" "unprognostic (1.27e-1)" "unprognostic (5.65e-2)" "unprognostic (2.29e-2)" "unprognostic (4.45e-2)" "unprognostic (9.14e-2)" "unprognostic (2.32e-2)" "unprognostic (5.73e-2)" "unprognostic (5.18e-2)" "unprognostic (5.92e-2)" "unprognostic (3.02e-1)" "unprognostic (2.48e-2)" "unprognostic (1.32e-1)" "unprognostic (9.72e-2)" 40.5 28.4 5.5 158.9 5.3 160.9 15.2 6.5 5.5 12.3 12.4 22.3 19.3 9.3 4.3 8.9 9.9 26.2 8.0 4.7 9.1 8.0 27.5 91.5 97.1 15.1 9.6 6.9 4.0 4.4 2.5 54.6 13.3 6.7 30.6 1.7 7.0 9.7 3.7 2.2 22.3 55.5 12.5 89.0 17.2 4.7 11.1 18.3 5.3 5.5 73.2 46.8 2.3 24.0 1.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 52.8 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.4 3.6 0.6 0.0 0.0 3.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.5 0.0 0.0 0.1 64.2 0.2 0.0 0.3 54.6 0.0 210.4 0.0 0.1 0.4 0.1 0.0 0.4 0.0 0.0 0.1 20.0 0.0 0.0 0.1 0.1 0.2 0.6 1.6 3.4 0.0 8.9 0.0 2.2 276.3 110.5 0.4 261.6 0.5 39.6 0.3 0.4 62.8 32.8 0.3 0.2 19.2 0.6 237.1 90.9 0.9 162.5 5.5 5.3 6.5 5.5 4.7 9.1 15.1 9.6 13.3 12.5 11.1 24.0 2.4 25.6 25.4 0.7 99.9 1.0 0.1 0.0 0.6 0.1 1.0 3.0 11.0 2.8 13.0 1.8 0.0 0.9 82.7 2.0 0.0 0.0 0.6 0.2 0.1 8.1 0.0 5.2 1.6 0.4 1.1 4.4 4.1 0.1 7.6 0.1 5.0 3.2 157.2 1.7 1.6 0.7 0.0 456.0 25.0 0.7 0.6 469.3 1.8 76.8 396.6 0.1 14.4 0.0 0.1 0.1 0.5 0.0 13.6 0.0 0.6 0.5 7.3 0.7 13.1 1.6 1.2 0.0 0.6 1.9 1.3 1.8 7.5 0.0 1.3 0.1 CYP26B1 P450RAI-2 ENSG00000003137 "Cytochrome P450 family 26 subfamily B member 1" Q9NR63 2 72129238-72147862 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.9;skin 1: 31.4" "Group enriched" "Detected in many" 4 "Leydig cells: 75.8;Peritubular cells: 229.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 9.8;HaCaT: 14.8;RH-30: 18.4;U-2 OS: 19.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA012567 Uncertain Approved Cytosol "Intracellular and membrane" No No "Cluster 27: Brain & Skin - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA012567: AB_1847429" "unprognostic (1.70e-1)" "unprognostic (1.05e-1)" "unprognostic (8.76e-2)" "unprognostic (2.19e-4)" "unprognostic (3.46e-2)" "unprognostic (4.40e-1)" "unprognostic (2.17e-4)" "unprognostic (8.41e-2)" "unprognostic (1.51e-1)" "unprognostic (1.40e-1)" "unprognostic (7.55e-3)" "unprognostic (1.52e-1)" "unprognostic (2.62e-2)" "unprognostic (1.77e-1)" "unprognostic (1.55e-1)" "unprognostic (9.44e-3)" "unprognostic (2.04e-2)" 26.2 4.3 12.0 1.9 3.3 0.1 15.0 12.3 7.0 5.0 0.4 3.2 3.7 2.5 1.5 3.9 5.5 1.1 8.5 6.7 1.3 8.8 1.0 2.7 4.9 48.0 10.4 4.5 0.6 0.8 9.3 3.3 49.9 2.6 1.2 4.2 9.9 7.3 5.9 31.4 4.7 1.6 0.0 3.5 1.2 13.8 0.7 19.3 14.4 2.3 2.9 3.2 4.2 3.5 0.6 5.9 0.0 0.1 9.8 4.0 5.9 0.9 0.1 0.2 0.2 1.8 0.5 0.0 0.5 0.7 3.0 14.8 8.5 0.0 0.1 0.0 2.7 0.0 7.0 0.9 0.2 0.0 0.3 0.0 0.5 0.0 0.3 3.0 1.1 4.0 0.6 0.1 0.9 2.9 0.0 0.1 0.0 0.1 1.0 0.1 18.4 0.0 0.0 1.3 0.6 0.1 3.0 0.0 3.5 1.2 0.3 0.9 0.0 1.6 19.3 9.0 3.0 0.1 1.2 0.0 6.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 3.3 12.3 7.0 6.7 1.3 48.0 10.4 49.9 0.0 0.7 3.5 2.4 0.0 0.0 2.0 1.2 14.7 1.1 0.8 0.6 0.2 2.3 0.8 1.4 4.3 0.2 0.0 0.0 0.1 0.0 1.1 0.0 0.2 4.1 0.2 0.2 19.0 1.8 5.3 5.3 0.0 0.9 15.6 0.0 0.3 0.0 1.5 34.6 0.8 0.1 0.0 0.7 0.0 0.0 6.1 19.1 9.6 75.8 0.4 7.2 0.0 0.0 7.4 0.0 2.0 0.5 0.4 1.5 229.9 0.0 0.5 0.2 0.1 0.2 0.3 0.0 5.7 20.7 1.5 3.8 1.6 9.7 0.1 0.8 7.5 0.1 0.4 CYP2C18 "CPCI, CYP2C, CYP2C17, P450IIC17" ENSG00000108242 "Cytochrome P450 family 2 subfamily C member 18" P33260 10 94683729-94736190 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 102.8;liver: 197.0;stomach 1: 67.2" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 68.8;Hepatocytes: 124.0;Proximal enterocytes: 62.5;Squamous epithelial cells: 22.8" "Cancer enhanced" "Detected in many" "liver cancer: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.2;OE19: 1.9" "Not detected" "Not detected" HPA074424 Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Plasma membrane" "HPA074424: " "unprognostic (2.40e-1)" "unprognostic (1.75e-2)" "unprognostic (2.69e-1)" "unprognostic (1.10e-2)" "unprognostic (1.32e-2)" "unprognostic (2.57e-1)" "unprognostic (2.71e-1)" "unprognostic (9.78e-2)" "unprognostic (2.28e-1)" "unprognostic (4.22e-3)" "unprognostic (1.62e-3)" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (6.81e-3)" 0.3 0.0 0.0 1.6 0.1 0.0 0.3 0.2 0.1 5.3 0.0 5.9 102.8 0.1 0.0 30.9 0.0 16.3 0.0 0.1 0.0 0.3 197.0 0.8 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 2.5 0.0 5.4 0.0 0.0 4.4 83.1 0.1 0.1 0.0 67.2 0.1 0.1 0.3 0.0 0.0 7.1 0.2 9.5 0.2 0.0 0.1 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.9 0.0 0.0 0.0 0.4 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.1 0.2 0.0 0.0 3.3 0.0 0.3 0.1 0.0 1.6 0.0 0.0 0.0 0.1 0.1 17.2 3.2 0.0 0.0 0.1 0.0 6.7 0.0 1.5 0.0 0.6 0.1 0.0 0.0 2.7 0.5 6.9 0.2 0.1 68.8 1.3 0.0 0.0 1.8 124.0 0.0 0.0 0.8 2.1 2.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 9.1 3.9 0.0 0.3 0.0 62.5 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.3 22.8 1.7 1.5 0.1 0.1 5.7 0.0 CYP2E1 CYP2E ENSG00000130649 "Cytochrome P450 family 2 subfamily E member 1" P05181 10 133520406-133561220 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 309 "liver: 10379.8" "Cell type enriched" "Detected in many" 58 "Hepatocytes: 6272.7" "Cancer enriched" "Detected in some" 278 "liver cancer: 265.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.5;myeloid DC: 6.2" "Group enriched" "Detected in many" 16 "dendritic cells: 6.2;T-cells: 2.5" "Cell line enhanced" "Detected in many" "HaCaT: 11.0;HL-60: 8.9;HMC-1: 8.9;NB-4: 24.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA009128, HPA029564" Enhanced Approved "Endoplasmic reticulum,Mitochondria" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 24: NB-4 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum, Mitochondria" "HPA009128: AB_1078613, HPA029564: AB_10602213" "unprognostic (6.32e-2)" "unprognostic (1.51e-2)" "unprognostic (3.83e-5)" "unprognostic (1.27e-1)" "unprognostic (3.37e-2)" "unprognostic (1.26e-1)" "unprognostic (2.92e-3)" "unprognostic (6.36e-3)" "unprognostic (2.41e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" "unprognostic (3.21e-2)" "unprognostic (1.70e-4)" "unprognostic (1.72e-1)" "unprognostic (8.36e-2)" "unprognostic (3.78e-1)" "unprognostic (9.59e-2)" 2.8 2.9 5.4 0.6 5.4 0.8 3.0 9.1 7.5 4.9 3.0 5.0 1.4 4.5 8.3 16.7 5.5 2.5 2.1 5.5 5.5 9.1 10379.8 2.6 2.0 6.1 5.5 4.1 12.4 0.6 4.1 1.4 6.7 5.3 1.2 11.5 3.6 6.1 2.8 13.8 2.2 2.2 5.0 7.2 6.7 3.7 6.3 1.7 4.0 0.9 33.6 3.5 3.2 7.5 0.1 0.0 0.3 1.0 3.5 1.9 0.7 1.6 4.5 0.0 0.3 0.0 2.7 1.4 0.2 0.5 0.0 11.0 0.0 0.2 0.4 0.3 1.5 1.8 0.2 1.3 0.6 8.9 8.9 1.0 0.2 0.0 0.7 1.9 0.0 3.1 0.6 0.4 1.0 0.7 0.6 24.0 6.4 4.3 0.4 0.4 6.1 0.0 2.0 0.0 0.0 0.0 4.2 0.0 0.6 0.2 0.3 0.9 0.0 1.4 0.4 2.3 1.0 2.2 1.0 3.0 1.5 7.4 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 1.1 0.6 6.2 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.2 5.4 5.4 9.1 7.5 5.5 5.5 6.1 5.5 6.7 5.0 6.3 7.5 0.8 0.0 1.1 5.5 9.2 2.3 0.2 0.7 0.6 5.7 0.6 0.5 2.8 48.6 1.9 0.0 2.1 0.0 0.4 0.1 0.0 1.6 2.1 0.6 0.8 4.6 0.0 67.6 6.7 1.3 0.1 1.1 1.5 0.5 1.3 0.7 67.1 6272.7 0.0 8.4 5.3 0.0 0.0 108.0 2.8 2.1 1.5 0.3 0.0 1.9 0.4 0.7 0.0 2.0 2.2 3.2 0.0 2.6 0.3 0.6 0.0 0.6 2.2 5.8 0.0 0.2 0.6 4.1 4.2 2.0 7.5 0.1 5.7 0.2 0.0 0.0 CYP2J2 ENSG00000134716 "Cytochrome P450 family 2 subfamily J member 2" P51589 1 59893308-59926773 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 89.7;intestine: 83.4;liver: 146.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 91.4;Cytotrophoblasts: 116.2;Hepatocytes: 58.3;Oligodendrocytes: 68.5;Proximal enterocytes: 134.6;Syncytiotrophoblasts: 240.9" "Cancer enhanced" "Detected in many" "renal cancer: 32.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.9;naive CD8 T-cell: 2.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "OE19: 16.9;RT4: 62.3;SK-BR-3: 16.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (3.53e-2)" "unprognostic (1.22e-2)" "unprognostic (1.35e-2)" "unprognostic (1.99e-2)" "unprognostic (2.51e-2)" "unprognostic (2.28e-1)" "unprognostic (1.61e-1)" "unprognostic (3.16e-1)" "unprognostic (1.15e-1)" "unprognostic (2.84e-2)" "unprognostic (7.29e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (5.54e-7)" "unprognostic (4.96e-1)" "unprognostic (8.45e-2)" "unprognostic (4.25e-1)" "unprognostic (9.70e-2)" 1.2 0.4 18.3 1.2 22.1 0.1 9.3 23.6 19.1 2.3 8.4 19.0 34.1 1.0 0.8 13.1 0.9 2.0 89.7 14.7 19.4 3.0 146.2 1.4 0.2 20.7 20.7 0.0 2.2 0.0 0.9 22.3 18.9 3.3 21.3 3.5 14.5 0.7 25.3 8.9 83.4 1.8 20.2 0.1 4.7 0.6 28.0 0.5 0.1 6.4 0.7 5.8 3.6 21.8 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 2.7 0.1 1.2 0.3 2.8 0.0 0.8 0.0 3.5 0.9 0.0 0.9 0.0 0.0 1.7 0.0 0.0 0.5 0.0 0.0 0.1 0.5 0.9 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.6 3.2 0.0 0.0 1.5 16.9 2.6 0.0 6.3 0.0 3.4 62.3 0.9 3.8 0.1 16.4 0.6 0.1 4.1 0.0 0.0 2.2 2.5 0.0 0.9 1.9 0.1 0.0 0.5 0.0 6.9 0.0 0.0 0.0 0.1 0.0 0.6 0.8 0.3 0.2 0.0 0.4 2.9 2.6 0.0 0.4 0.0 0.6 0.0 0.4 18.3 22.1 23.6 19.1 14.7 19.4 20.7 20.7 18.9 20.2 28.0 21.8 0.0 3.2 4.1 35.6 0.7 0.4 1.7 5.5 7.4 0.0 5.1 3.0 91.4 11.5 28.9 0.0 0.0 116.2 0.1 26.4 0.0 9.5 22.7 3.1 1.7 1.3 9.0 0.0 0.1 0.9 9.3 2.3 4.1 7.7 0.0 1.5 0.0 58.3 7.0 0.0 0.4 18.7 6.1 0.8 0.3 23.3 0.0 0.2 0.0 1.9 0.6 12.5 0.0 29.7 68.5 2.0 18.1 0.0 0.3 1.5 134.6 2.5 20.1 0.9 0.0 0.7 1.0 0.3 0.2 7.3 2.3 240.9 0.2 0.4 24.1 2.1 CYP2S1 ENSG00000167600 "Cytochrome P450 family 2 subfamily S member 1" Q96SQ9 19 41193210-41207539 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 101.3;stomach 1: 120.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 31.0;Gastric mucus-secreting cells: 110.6;Intestinal goblet cells: 29.2;Langerhans cells: 73.0;Proximal enterocytes: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 24.7;myeloid DC: 84.4" "Group enriched" "Detected in many" 131 "dendritic cells: 84.4;monocytes: 24.7" "Cell line enhanced" "Detected in many" "A549: 99.4;CACO-2: 49.8;HaCaT: 50.3;NTERA-2: 69.6;OE19: 158.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049227, HPA069248" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "HPA049227: AB_2680681, HPA069248: AB_2732128" "unprognostic (1.49e-2)" "unprognostic (7.45e-2)" "unprognostic (2.45e-2)" "unprognostic (6.03e-2)" "unprognostic (3.93e-2)" "unprognostic (7.46e-2)" "unprognostic (1.27e-2)" "unprognostic (4.85e-2)" "unprognostic (2.18e-1)" "unprognostic (1.54e-2)" "unprognostic (6.25e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.60e-6)" "unprognostic (1.06e-1)" "unprognostic (1.10e-1)" "unprognostic (1.02e-1)" "unprognostic (7.66e-2)" 1.8 1.1 1.4 6.7 1.4 1.8 0.9 3.1 1.5 2.7 1.2 26.7 101.3 0.5 0.2 14.5 6.3 5.5 0.5 1.3 4.1 1.1 1.4 7.1 1.7 6.3 10.0 0.3 0.6 0.7 1.2 1.6 6.1 1.3 18.6 0.2 5.0 0.9 0.2 3.7 65.3 1.7 2.2 6.1 120.4 0.8 3.6 3.2 0.6 0.2 13.2 3.6 4.0 2.5 3.8 99.4 0.0 0.1 0.0 0.0 4.5 0.6 0.8 1.0 0.2 49.8 13.6 0.2 10.4 0.7 0.1 50.3 16.6 25.0 0.4 0.0 0.3 12.9 5.1 19.1 19.4 0.0 0.4 0.8 1.4 1.4 0.8 0.2 0.8 4.3 5.8 0.2 0.0 2.0 0.3 0.2 69.6 158.6 12.5 0.2 0.0 0.9 1.5 20.4 0.1 0.6 9.1 0.0 0.0 27.8 12.2 4.7 10.6 0.1 4.0 1.7 0.0 0.5 0.0 0.0 0.5 2.1 0.1 0.0 24.7 0.0 0.0 5.9 0.4 0.0 0.0 0.1 84.4 0.0 0.0 0.0 0.2 0.1 3.7 3.2 0.0 11.4 1.4 1.4 3.1 1.5 1.3 4.1 6.3 10.0 6.1 2.2 3.6 2.5 0.3 0.0 6.9 1.0 0.7 2.5 2.0 18.2 23.3 0.0 0.1 0.3 1.2 0.0 7.6 1.8 0.0 24.9 0.1 31.0 0.0 0.7 0.3 7.4 0.3 0.4 0.0 0.0 0.4 1.0 1.1 0.8 110.6 0.3 1.3 0.1 0.4 0.0 14.5 0.0 0.5 29.2 0.0 5.7 73.0 0.0 0.0 16.0 0.0 1.0 7.2 0.0 0.0 0.5 0.1 23.7 22.3 0.0 0.4 0.5 50.7 0.2 10.8 0.0 0.0 0.3 0.9 0.1 0.4 4.0 2.8 10.3 0.3 0.0 14.1 0.5 CYP3A7-CYP3A51P ENSG00000282301 "CYP3A7-CYP3A51P readthrough" 7 99684957-99735102 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 12.7" "Group enriched" "Detected in some" 10 "Cholangiocytes: 4.3;Hepatocytes: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 15: Hepatocytes - Hemostasis" Cytosol Vesicles "HPA072245: , HPA075539: " 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 1.1 0.1 0.0 0.0 1.5 12.7 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.5 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.2 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.2 0.2 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CYP46A1 CYP46 ENSG00000036530 "Cytochrome P450 family 46 subfamily A member 1" Q9Y6A2 14 99684298-99727301 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 96.2" "Cell type enhanced" "Detected in many" "Astrocytes: 58.1;Cone photoreceptor cells: 66.7;Excitatory neurons: 53.0;Inhibitory neurons: 41.6;Rod photoreceptor cells: 28.4" "Cancer enriched" "Detected in single" 5 "glioma: 1.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 23 "plasmacytoid DC: 3.4" "Lineage enriched" "Detected in single" 23 "dendritic cells: 3.4" "Group enriched" "Detected in some" 4 "AF22: 2.4;U-937: 6.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 32: U-937 - Innate immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "unprognostic (2.16e-1)" "unprognostic (4.30e-1)" "unprognostic (2.50e-5)" "unprognostic (9.48e-5)" "unprognostic (1.15e-1)" "unprognostic (5.92e-2)" "unprognostic (3.45e-2)" "unprognostic (1.06e-1)" "unprognostic (5.37e-2)" "unprognostic (4.01e-2)" "unprognostic (1.32e-5)" "unprognostic (5.21e-2)" "unprognostic (2.44e-4)" "unprognostic (5.97e-4)" "unprognostic (1.59e-1)" "unprognostic (1.15e-2)" "unprognostic (3.88e-3)" 1.9 2.0 45.7 0.3 96.2 0.0 0.8 20.1 66.7 1.4 17.5 0.7 0.2 1.5 0.9 0.2 1.0 0.4 4.7 52.7 34.0 1.4 1.3 0.6 0.6 25.3 32.0 1.6 2.1 1.9 16.6 0.0 26.2 1.4 0.2 5.1 1.4 0.6 1.1 0.4 0.5 0.8 23.5 0.2 0.7 2.5 38.2 0.4 1.7 0.5 0.1 0.9 0.7 39.0 0.0 0.0 2.4 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.0 1.1 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.1 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 45.7 96.2 20.1 66.7 52.7 34.0 25.3 32.0 26.2 23.5 38.2 39.0 3.5 3.2 6.0 58.1 0.7 1.7 6.4 0.0 1.2 11.5 1.8 3.3 7.0 2.8 1.8 1.8 66.7 0.2 8.7 0.0 1.9 0.2 0.7 0.9 5.0 7.6 0.0 0.0 53.0 1.1 0.3 4.0 0.5 0.6 1.3 2.1 2.9 3.4 0.6 8.4 41.6 0.0 0.0 2.1 3.0 1.3 4.7 0.9 3.6 6.5 1.1 20.8 0.0 23.6 11.8 0.1 0.1 4.1 2.2 4.1 0.0 7.4 0.9 28.4 0.0 8.1 3.9 9.4 5.3 0.0 1.4 0.1 1.5 2.7 0.1 3.5 CYP4F11 ENSG00000171903 "Cytochrome P450 family 4 subfamily F member 11" Q9HBI6 19 15912367-15934867 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.9;liver: 72.3" "Cell type enhanced" "Detected in many" "Ductal cells: 15.6;Hepatocytes: 62.9;Prostatic glandular cells: 36.3;Urothelial cells: 26.1" "Cancer enhanced" "Detected in many" "liver cancer: 25.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 13.1;CAPAN-2: 50.4;EFO-21: 18.5;Hep G2: 25.0;RPMI-8226: 13.5;RT4: 15.2" "HPA017265, CAB033648, HPA058960" Enhanced "Intracellular and membrane" NA NA "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "CAB033648: AB_2088410, HPA017265: AB_1847451, HPA058960: AB_2683862" "prognostic favorable (4.05e-4)" "unprognostic (4.12e-2)" "unprognostic (1.79e-1)" "unprognostic (5.99e-2)" "unprognostic (5.92e-3)" "unprognostic (1.06e-2)" "unprognostic (1.24e-1)" "unprognostic (1.65e-1)" "unprognostic (2.33e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (9.28e-4)" "unprognostic (4.44e-2)" "unprognostic (9.50e-3)" "unprognostic (2.14e-2)" "unprognostic (2.24e-1)" "unprognostic (2.78e-2)" "unprognostic (4.64e-2)" 0.3 2.9 5.2 0.6 5.3 0.6 2.1 5.1 5.3 1.6 0.0 3.5 10.7 0.5 16.4 13.0 3.0 18.7 0.2 4.3 5.5 6.4 72.3 0.6 0.4 9.3 9.6 0.1 5.1 0.1 0.5 0.1 6.3 3.8 2.6 1.6 3.8 4.3 0.5 1.0 23.9 0.1 4.8 1.0 4.1 1.1 6.6 0.0 3.0 0.0 0.9 5.7 3.4 5.0 13.1 2.4 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 50.4 0.1 18.5 0.0 10.5 1.5 0.0 6.6 0.0 0.0 0.1 0.1 4.2 25.0 0.0 0.4 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.2 10.0 0.0 1.9 0.1 0.3 0.1 11.4 0.0 0.1 0.1 13.5 3.4 15.2 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.1 0.1 1.8 0.2 0.2 0.1 0.6 0.2 0.4 1.5 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 5.3 5.1 5.3 4.3 5.5 9.3 9.6 6.3 4.8 6.6 5.0 0.1 0.0 0.0 9.1 0.2 0.1 7.7 5.3 0.0 0.0 1.4 1.7 0.4 10.0 4.4 9.2 0.0 0.0 0.0 6.9 1.9 15.6 0.0 2.8 0.6 0.3 1.2 2.7 0.0 11.5 0.0 0.3 0.0 4.4 0.0 0.3 0.4 62.9 0.0 0.0 0.0 2.0 2.0 2.4 0.0 0.1 0.3 0.4 0.0 0.0 0.0 3.0 0.0 0.0 0.8 9.2 3.2 0.0 0.0 36.3 11.7 8.3 7.6 0.1 0.0 0.6 0.6 0.0 0.0 0.5 0.3 0.0 0.1 0.1 2.7 26.1 CYP4Z1 CYP4A20 ENSG00000186160 "Cytochrome P450 family 4 subfamily Z member 1" Q86W10 1 47067231-47118318 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 6.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Breast glandular cells: 8.3;Early spermatids: 2.5;Excitatory neurons: 8.3;Inhibitory neurons: 5.8" "Cancer enriched" "Detected in some" 50 "breast cancer: 42.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "HDLM-2: 8.1;SK-BR-3: 3.2" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (4.11e-2)" "unprognostic (2.57e-2)" "unprognostic (2.46e-1)" "unprognostic (5.12e-2)" "unprognostic (1.37e-1)" "unprognostic (4.33e-4)" "unprognostic (1.10e-1)" "unprognostic (3.53e-3)" "unprognostic (7.76e-3)" "unprognostic (1.21e-1)" "unprognostic (3.53e-1)" "unprognostic (6.82e-3)" "unprognostic (5.09e-3)" "unprognostic (3.88e-2)" "unprognostic (6.46e-2)" "unprognostic (3.49e-3)" 2.2 0.2 0.9 0.0 0.9 0.0 6.3 0.2 1.1 0.3 0.0 0.2 0.0 0.3 0.3 0.7 0.6 0.0 0.8 0.8 1.3 0.2 0.7 1.6 0.0 0.4 0.4 0.0 0.1 0.0 0.6 0.0 0.3 1.2 0.0 0.0 0.8 0.3 0.7 1.0 0.2 0.0 0.2 0.0 0.4 0.4 1.1 0.2 0.5 0.2 0.2 0.4 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.2 1.1 0.8 1.3 0.4 0.4 0.3 0.2 1.1 0.9 0.3 9.6 1.1 1.0 0.0 0.1 0.5 0.4 0.0 0.0 8.3 0.4 0.4 0.0 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.5 0.2 0.1 0.9 0.0 0.0 8.3 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 CYP51A1 "CP51, CYP51, CYPL1, LDM, P450-14DM, P450L1" ENSG00000001630 "Cytochrome P450 family 51 subfamily A member 1" Q16850 7 92112153-92134803 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Monooxygenase, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 204.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 67.3;Alveolar cells type 2: 169.7;Early spermatids: 74.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 481.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041325, HPA043508" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 37: Intestine - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 11: Alveolar cells - Smell perception" "Endoplasmic reticulum" "HPA041325: AB_2677411, HPA043508: AB_2678520" "unprognostic (6.68e-2)" "prognostic unfavorable (6.12e-4)" "unprognostic (3.48e-2)" "unprognostic (1.18e-2)" "unprognostic (7.82e-2)" "unprognostic (3.60e-2)" "unprognostic (1.02e-1)" "unprognostic (1.97e-1)" "unprognostic (9.84e-2)" "unprognostic (1.36e-1)" "unprognostic (9.75e-2)" "unprognostic (1.34e-1)" "unprognostic (1.59e-9)" "unprognostic (1.82e-1)" "unprognostic (2.73e-1)" "unprognostic (5.13e-2)" "unprognostic (1.09e-3)" 19.4 58.2 22.3 20.6 24.9 30.3 30.6 39.8 32.3 26.4 21.0 52.7 86.6 21.2 35.8 43.7 16.7 24.3 20.7 24.2 39.0 38.7 204.7 53.2 13.1 60.1 42.3 29.0 48.7 59.6 17.1 21.9 50.6 43.8 41.5 31.4 20.3 17.5 7.9 26.5 40.0 20.4 46.6 13.4 45.1 86.4 31.8 6.6 33.6 11.7 16.6 21.3 26.2 57.0 113.7 54.3 134.0 86.4 92.0 149.6 18.7 37.7 112.7 47.1 128.8 131.8 201.7 98.1 57.9 65.3 481.6 96.2 118.1 237.0 55.3 40.3 82.6 27.9 51.1 99.7 125.7 56.0 39.4 109.1 105.7 185.6 194.0 42.2 49.4 19.8 108.2 217.8 56.4 115.6 12.5 53.8 100.7 45.9 53.4 40.3 27.8 222.8 216.7 187.9 94.1 62.5 80.0 156.3 117.2 60.6 56.9 69.5 59.5 65.0 70.6 95.2 49.8 72.8 70.5 88.1 49.8 75.5 85.2 2.8 11.1 3.9 11.6 16.3 7.7 15.6 8.0 8.9 16.3 12.3 7.1 9.6 1.5 7.8 10.3 14.3 6.7 8.2 22.3 24.9 39.8 32.3 24.2 39.0 60.1 42.3 50.6 46.6 31.8 57.0 3.1 67.3 169.7 35.9 24.0 2.5 1.6 4.6 48.9 2.6 6.7 3.7 1.6 7.2 44.5 1.8 2.1 1.5 8.9 20.3 1.9 10.7 74.4 10.7 8.1 7.7 10.8 11.6 34.3 19.8 1.0 9.1 43.3 16.4 28.5 4.1 5.3 45.2 1.5 0.0 39.6 13.1 2.0 5.6 1.9 34.4 3.7 9.2 0.0 15.9 1.3 2.4 0.0 39.2 53.1 14.2 11.7 1.5 34.3 1.4 9.6 1.5 15.7 1.9 0.0 4.0 6.5 7.8 4.2 51.4 5.4 4.4 12.2 9.3 11.9 2.5 CYP7B1 SPG5A ENSG00000172817 "Cytochrome P450 family 7 subfamily B member 1" O75881 8 64587763-64798737 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Disease variant, Hereditary spastic paraplegia, Intrahepatic cholestasis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.2" "Cell type enhanced" "Detected in many" "Astrocytes: 93.7;Oligodendrocyte precursor cells: 94.5;Oligodendrocytes: 119.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "basophil: 2.5;eosinophil: 1.5" "Lineage enriched" "Detected in single" 25 "granulocytes: 2.5" "Group enriched" "Detected in some" 4 "HSkMC: 16.5;SH-SY5Y: 5.5;WM-115: 10.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017761 Uncertain NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "HPA017761: AB_1847455" "unprognostic (3.19e-2)" "unprognostic (1.91e-1)" "unprognostic (1.50e-1)" "unprognostic (6.89e-3)" "unprognostic (1.07e-1)" "unprognostic (5.80e-3)" "unprognostic (3.80e-1)" "unprognostic (5.50e-2)" "unprognostic (6.11e-3)" "unprognostic (2.46e-1)" "unprognostic (1.61e-1)" "unprognostic (3.19e-2)" "unprognostic (1.87e-2)" "unprognostic (2.38e-3)" "unprognostic (4.00e-1)" "unprognostic (3.04e-3)" "unprognostic (6.75e-3)" 8.4 5.4 5.7 5.6 11.4 0.3 6.3 8.2 6.6 5.7 8.6 2.3 1.8 2.8 2.0 7.3 2.7 5.8 3.6 5.3 6.8 7.9 21.5 4.6 2.4 11.8 7.3 4.2 6.7 11.4 0.8 0.5 11.4 4.4 3.5 1.9 4.6 5.6 0.2 5.9 1.8 4.3 8.4 9.2 2.4 1.7 8.1 2.1 12.2 1.7 2.9 7.9 3.0 27.2 1.5 0.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.6 5.5 0.0 0.0 2.2 0.8 0.0 1.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 2.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.7 11.4 8.2 6.6 5.3 6.8 11.8 7.3 11.4 8.4 8.1 27.2 3.3 0.0 3.4 93.7 0.1 10.6 6.6 1.0 7.4 4.9 4.2 5.5 3.0 2.8 0.9 7.3 2.1 0.1 0.4 0.0 3.9 4.4 7.4 0.2 6.9 2.1 1.8 1.3 29.3 4.9 0.2 15.9 0.5 0.1 12.7 0.6 2.5 8.2 0.2 3.3 30.6 0.5 0.0 0.3 4.9 8.6 5.9 0.5 17.8 30.0 1.0 6.9 0.0 94.5 119.2 1.2 0.0 4.9 0.0 4.2 0.0 2.9 0.8 0.5 13.1 1.1 16.8 4.1 3.4 6.2 12.6 0.0 1.3 7.6 0.0 3.1 CYP8B1 CYP12 ENSG00000180432 "Cytochrome P450 family 8 subfamily B member 1" Q9UNU6 3 42856005-42875898 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "liver: 404.5" "Cell type enriched" "Detected in some" 76 "Hepatocytes: 920.2" "Cancer enriched" "Detected in some" 46 "liver cancer: 69.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.4;SK-BR-3: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 28: BEWO - Transcription regulation" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.58e-2)" "unprognostic (5.41e-2)" "unprognostic (6.38e-2)" "unprognostic (1.15e-2)" "unprognostic (8.95e-2)" "unprognostic (1.42e-3)" "unprognostic (4.47e-3)" "unprognostic (1.49e-1)" "unprognostic (9.85e-2)" "unprognostic (4.04e-3)" "unprognostic (5.86e-3)" "unprognostic (2.74e-1)" "unprognostic (3.37e-1)" "unprognostic (1.03e-1)" "unprognostic (3.63e-1)" "unprognostic (3.19e-1)" "unprognostic (1.24e-1)" 0.3 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.9 0.2 0.1 0.5 0.1 0.2 0.1 14.4 404.5 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.4 0.1 0.0 0.0 0.2 0.1 0.1 0.2 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.2 0.1 0.1 0.1 0.0 0.0 0.2 1.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 8.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 5.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 7.9 920.2 0.1 0.0 0.0 0.0 0.0 10.7 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 CYS1 ENSG00000205795 "Cystin 1" Q717R9 2 10056780-10080944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 124.6;pancreas: 33.6" "Group enriched" "Detected in many" 4 "Cholangiocytes: 32.9;Collecting duct cells: 51.5;Distal tubular cells: 70.5;Muller glia cells: 48.0;Proximal tubular cells: 54.1" "Cancer enhanced" "Detected in many" "renal cancer: 46.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "RPTEC TERT1: 111.5" "Low region specificity" "Detected in all" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (8.48e-2)" "unprognostic (8.00e-2)" "unprognostic (9.17e-2)" "unprognostic (1.63e-1)" "unprognostic (1.00e-2)" "unprognostic (2.80e-1)" "unprognostic (1.56e-1)" "unprognostic (5.71e-2)" "unprognostic (1.94e-2)" "unprognostic (9.53e-2)" "unprognostic (7.05e-2)" "unprognostic (7.03e-2)" "prognostic favorable (1.27e-5)" "unprognostic (2.19e-3)" "unprognostic (1.47e-1)" "unprognostic (8.93e-2)" "unprognostic (1.20e-2)" 3.1 1.6 6.0 1.2 5.7 0.0 1.9 5.3 7.8 8.4 15.5 11.7 2.5 7.8 3.6 3.9 6.3 9.1 6.1 5.5 5.5 124.6 1.0 6.1 1.1 6.9 6.0 12.4 33.6 1.7 7.2 0.1 5.6 4.9 1.8 2.2 2.9 7.2 1.0 1.5 3.4 5.9 6.4 2.9 3.9 1.0 5.2 0.5 5.6 2.1 2.1 3.5 6.6 5.9 0.0 0.3 0.0 0.0 0.5 2.6 0.1 0.4 1.6 0.2 0.1 0.2 0.0 0.0 0.4 4.4 0.9 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 3.7 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 111.5 0.0 0.0 0.5 0.4 0.3 0.0 1.3 2.0 0.2 0.0 6.0 3.2 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 5.7 5.3 7.8 5.5 5.5 6.9 6.0 5.6 6.4 5.2 5.9 0.9 6.4 1.1 1.0 1.0 0.5 0.1 0.6 0.0 10.3 0.5 5.5 7.3 32.9 0.0 51.5 0.0 0.0 0.2 0.0 70.5 7.0 0.1 0.3 0.9 0.6 0.0 0.0 2.9 1.1 0.6 8.8 0.0 4.6 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.3 0.0 3.4 1.0 0.0 2.8 0.0 48.0 0.0 3.0 0.6 0.4 0.0 4.5 0.1 0.3 0.0 54.1 0.0 1.9 0.0 0.5 3.9 0.0 1.4 0.0 0.1 0.0 0.3 0.1 0.0 0.1 CYYR1 C21orf95 ENSG00000166265 "Cysteine and tyrosine rich 1" Q96J86 21 26466209-26573286 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 200.0;Endothelial cells: 150.0;Hepatic stellate cells: 79.9;Microglial cells: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 38 "plasmacytoid DC: 31.4" "Lineage enriched" "Detected in single" 82 "dendritic cells: 31.4" "Cell line enhanced" "Detected in some" "AF22: 14.1;NTERA-2: 39.2;PC-3: 11.0;RH-30: 16.6;SCLC-21H: 33.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034921, HPA067685" Uncertain Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB034921: AB_2089315, HPA067685: AB_2685887" "unprognostic (5.64e-2)" "unprognostic (2.59e-2)" "unprognostic (1.37e-1)" "unprognostic (1.88e-1)" "unprognostic (7.00e-2)" "unprognostic (2.63e-2)" "unprognostic (2.88e-3)" "unprognostic (4.04e-1)" "unprognostic (1.11e-2)" "unprognostic (1.12e-1)" "unprognostic (3.77e-2)" "unprognostic (1.46e-1)" "unprognostic (2.44e-3)" "unprognostic (9.29e-3)" "unprognostic (2.26e-1)" "unprognostic (1.88e-1)" "unprognostic (1.49e-2)" 36.4 46.4 9.7 8.1 9.0 7.8 30.2 8.7 11.4 16.4 8.4 8.4 6.1 19.2 8.1 9.0 12.9 16.1 22.3 8.1 9.4 12.7 4.8 23.7 6.0 9.9 10.5 4.5 5.5 15.5 3.8 36.3 10.6 9.5 6.6 0.9 6.8 11.4 15.1 8.2 9.6 23.6 9.6 32.5 7.7 1.9 10.8 6.0 14.1 31.8 4.6 12.6 9.5 9.4 0.0 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 7.1 1.6 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 6.5 0.0 0.4 0.0 5.6 0.0 0.0 0.0 2.6 0.0 0.0 0.1 39.2 0.0 11.0 0.0 16.6 0.0 1.7 0.0 33.7 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 3.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 31.4 0.0 0.1 9.7 9.0 8.7 11.4 8.1 9.4 9.9 10.5 10.6 9.6 10.8 9.4 200.0 0.0 0.6 1.6 1.5 11.7 2.0 10.2 27.3 0.1 14.9 15.0 6.7 0.0 1.7 14.7 0.0 0.1 14.9 0.0 3.9 0.0 0.7 0.4 6.9 150.0 0.0 11.1 1.6 0.0 0.2 8.3 0.0 0.4 0.0 3.7 79.9 0.4 0.3 0.0 4.6 0.0 2.0 3.2 8.0 1.5 2.1 1.4 7.2 58.1 0.7 0.5 0.0 0.0 0.7 0.1 0.0 0.0 2.5 1.1 0.0 6.8 1.1 0.3 0.0 13.3 4.4 0.2 1.3 4.9 5.4 0.3 1.5 0.4 0.0 0.7 DACT3 "DAPPER3, MGC15476, RRR1" ENSG00000197380 "Dishevelled binding antagonist of beta catenin 3" Q96B18 19 46647551-46661182 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 23.9;Oligodendrocytes: 27.2;Smooth muscle cells: 22.9" "Cancer enhanced" "Detected in many" "glioma: 7.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 10.5;SH-SY5Y: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043053 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles Nucleoplasm "HPA043053: AB_10794769" "unprognostic (2.35e-1)" "unprognostic (3.08e-1)" "unprognostic (5.30e-3)" "unprognostic (5.08e-2)" "unprognostic (2.02e-1)" "unprognostic (1.09e-1)" "unprognostic (2.66e-1)" "unprognostic (2.03e-2)" "unprognostic (3.27e-2)" "unprognostic (2.03e-4)" "unprognostic (1.70e-1)" "unprognostic (2.67e-1)" "prognostic unfavorable (7.97e-8)" "unprognostic (1.59e-2)" "unprognostic (4.03e-2)" "unprognostic (3.54e-3)" "prognostic unfavorable (6.66e-4)" 9.1 3.3 42.1 5.9 42.0 1.4 5.4 41.1 54.4 34.7 3.6 53.9 3.9 48.2 14.3 7.4 37.4 7.2 27.5 48.6 33.4 5.9 2.6 14.0 1.1 45.4 40.1 17.0 1.1 1.9 4.1 1.7 39.9 19.7 6.7 5.8 1.7 24.6 2.2 4.1 13.0 31.6 34.7 6.8 18.0 18.7 46.3 0.5 4.8 2.9 0.9 39.0 15.9 58.0 0.2 0.2 5.6 5.3 1.9 1.5 0.5 3.1 5.2 1.0 1.5 0.2 0.3 0.5 2.0 10.5 1.0 0.3 3.6 0.1 1.0 0.3 1.9 1.2 0.8 0.2 2.7 0.1 2.1 4.9 0.1 1.3 0.1 0.6 0.4 0.7 1.8 1.8 0.9 0.4 0.2 1.4 2.2 0.0 0.8 4.6 1.3 0.3 0.2 0.3 2.1 24.6 0.4 0.2 0.4 5.7 0.4 0.5 0.4 2.6 3.2 2.6 0.5 1.6 0.5 0.8 0.5 0.8 1.9 2.6 0.3 0.3 0.2 0.1 0.1 0.3 0.2 0.2 0.1 0.5 0.2 0.2 1.6 0.7 0.2 0.3 0.2 0.1 42.1 42.0 41.1 54.4 48.6 33.4 45.4 40.1 39.9 34.7 46.3 58.0 1.9 6.4 5.5 13.7 0.2 2.3 1.5 0.0 0.0 16.5 1.0 2.4 17.8 1.5 0.7 0.0 2.1 5.4 0.5 0.3 0.0 0.0 23.9 0.4 9.3 3.1 1.8 0.0 9.2 0.0 2.6 7.4 0.0 0.8 6.3 0.5 1.8 0.2 1.1 1.7 16.7 0.2 2.0 1.6 9.2 8.6 7.8 1.4 3.6 7.5 1.2 9.2 2.1 15.1 27.2 0.1 1.2 14.7 0.1 1.0 0.2 0.3 0.2 6.3 6.6 2.3 22.9 2.3 2.5 0.4 3.3 9.9 1.0 4.3 0.2 1.0 DAP ENSG00000112977 "Death associated protein" P51397 5 10679230-10761234 "Predicted intracellular proteins" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 193.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA029456 Uncertain Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "Vesicles, Mitochondria" Nucleoplasm "HPA029456: AB_10601262" "unprognostic (2.70e-2)" "unprognostic (3.48e-1)" "unprognostic (2.25e-1)" "unprognostic (1.88e-2)" "unprognostic (1.95e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (4.05e-2)" "unprognostic (1.19e-1)" "unprognostic (1.52e-3)" "unprognostic (3.50e-1)" "unprognostic (1.91e-2)" "unprognostic (3.03e-3)" "unprognostic (2.11e-1)" "unprognostic (2.39e-1)" "unprognostic (8.58e-3)" "unprognostic (2.04e-2)" 54.5 103.7 34.8 47.0 33.6 44.5 69.0 30.6 38.8 75.1 91.0 65.8 93.8 59.0 68.6 39.0 63.1 83.3 60.9 35.4 32.9 99.0 161.8 64.9 45.6 39.9 37.1 75.0 241.4 82.9 80.9 64.1 33.1 76.7 69.1 13.8 129.4 92.2 9.4 46.9 87.0 63.6 34.7 46.3 106.3 27.3 36.6 41.2 92.9 14.7 50.8 87.9 49.0 32.5 107.3 76.3 92.6 86.3 169.6 203.6 102.8 255.3 394.4 189.5 217.8 54.7 88.9 46.3 163.8 318.4 119.6 20.6 58.3 151.7 205.1 245.3 42.5 62.2 137.9 136.0 159.7 117.7 44.6 105.4 51.9 124.5 223.3 109.1 358.4 51.1 73.5 152.5 188.2 85.0 63.1 74.9 33.7 143.9 172.9 86.0 40.9 76.8 250.1 195.2 62.7 84.3 261.2 105.2 69.6 70.6 83.4 170.4 177.4 116.8 125.9 78.1 137.6 85.1 118.6 68.3 115.4 225.3 179.3 40.7 78.0 45.0 32.7 70.7 38.5 39.8 33.6 29.0 76.8 25.9 24.4 24.4 63.4 33.1 72.1 62.3 39.3 62.2 34.8 33.6 30.6 38.8 35.4 32.9 39.9 37.1 33.1 34.7 36.6 32.5 29.0 16.0 44.7 8.5 36.7 19.2 62.6 14.1 19.9 8.9 90.4 39.2 12.3 72.9 27.3 53.3 6.2 66.2 42.3 75.6 133.1 97.3 13.3 45.0 31.7 38.4 44.3 23.4 5.5 193.0 98.5 45.1 61.7 58.1 35.0 68.9 41.0 109.1 52.3 5.0 7.8 115.3 10.2 49.9 34.2 33.4 29.8 56.5 28.4 35.6 44.2 29.8 32.0 22.6 6.2 124.8 69.0 34.3 74.8 78.6 133.5 100.5 15.1 8.1 0.0 18.6 41.8 30.7 7.1 15.7 18.2 101.0 24.1 43.0 70.4 108.8 DARS2 "FLJ10514, mtAspRS" ENSG00000117593 "Aspartyl-tRNA synthetase 2, mitochondrial" Q6PI48 1 173824653-173858808 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026506, HPA026528" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria Nucleoplasm "HPA026506: AB_1847482, HPA026528: AB_1847483" "unprognostic (3.14e-2)" "unprognostic (1.52e-1)" "unprognostic (1.06e-1)" "unprognostic (8.85e-3)" "unprognostic (1.33e-1)" "unprognostic (1.14e-2)" "unprognostic (1.05e-3)" "unprognostic (4.10e-3)" "unprognostic (2.20e-1)" "unprognostic (1.42e-1)" "unprognostic (6.17e-2)" "unprognostic (1.15e-1)" "prognostic favorable (1.74e-4)" "unprognostic (3.30e-1)" "unprognostic (1.90e-1)" "unprognostic (1.13e-1)" "unprognostic (4.73e-3)" 8.8 9.8 3.1 7.6 3.5 5.4 7.5 3.7 4.3 7.1 11.5 14.6 8.7 4.3 4.7 6.4 5.2 4.8 8.4 3.1 3.8 19.9 13.5 5.7 9.2 3.3 3.6 4.4 5.7 15.5 2.9 7.6 3.4 5.3 15.4 5.2 5.2 5.0 5.6 3.4 10.4 5.6 3.5 6.2 9.3 6.2 3.9 10.6 7.6 13.5 12.0 6.7 4.1 3.7 74.8 50.5 26.3 18.7 24.0 34.2 38.6 32.3 30.0 49.2 37.0 47.5 68.2 41.6 45.2 27.2 31.3 77.5 86.6 56.5 66.7 48.6 41.5 35.2 22.7 31.8 24.0 30.9 30.8 23.2 25.3 50.9 44.5 15.4 49.8 30.5 74.7 31.0 39.6 19.9 38.8 16.1 60.2 83.0 63.2 44.3 40.6 78.2 43.7 24.9 40.4 34.2 36.3 79.6 51.3 47.0 84.5 39.7 21.2 22.9 35.3 32.6 52.5 21.7 60.4 46.3 13.3 33.3 51.5 3.9 4.4 3.3 3.8 7.0 5.4 6.0 3.4 3.2 6.4 4.4 3.8 2.6 0.2 3.5 5.0 2.5 3.9 3.5 3.1 3.5 3.7 4.3 3.1 3.8 3.3 3.6 3.4 3.5 3.9 3.7 3.7 3.2 3.1 7.2 5.7 1.8 4.1 3.1 6.2 2.3 3.3 2.5 12.6 4.3 4.2 5.5 0.0 9.7 3.1 4.8 7.9 3.9 2.5 3.9 4.9 4.5 4.2 9.4 5.3 2.7 16.0 3.9 7.1 4.5 5.7 4.5 1.8 5.4 10.3 3.3 6.5 5.2 0.0 4.4 2.2 1.5 3.1 5.1 1.8 8.4 5.6 2.9 3.1 4.0 5.1 3.8 1.9 1.5 7.1 2.6 5.9 7.1 3.0 2.7 0.0 6.2 4.0 8.9 7.1 8.0 1.6 4.2 4.4 9.2 7.2 2.9 DBN1 D0S117E ENSG00000113758 "Drebrin 1" Q16643 5 177456608-177474401 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 87.1;Pancreatic endocrine cells: 64.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 5.8;granulocytes: 9.4;T-cells: 14.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051452, HPA056940" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA 2000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Actin filaments" "HPA051452: AB_2681489, HPA056940: AB_2683279" "unprognostic (3.81e-2)" "unprognostic (6.60e-3)" "unprognostic (2.88e-2)" "unprognostic (7.57e-3)" "unprognostic (9.32e-2)" "unprognostic (5.68e-2)" "unprognostic (2.01e-3)" "unprognostic (4.29e-2)" "unprognostic (1.73e-2)" "unprognostic (7.92e-2)" "unprognostic (2.94e-2)" "unprognostic (3.64e-1)" "prognostic favorable (8.28e-4)" "unprognostic (1.53e-1)" "unprognostic (4.56e-2)" "unprognostic (1.05e-1)" "unprognostic (1.76e-3)" 59.4 9.3 44.8 17.6 52.5 6.4 36.5 19.3 71.7 59.7 18.6 67.6 9.5 84.4 10.2 30.9 44.7 24.4 39.7 70.1 45.4 52.0 4.0 24.7 9.0 33.8 25.4 34.8 16.9 17.1 45.8 7.1 32.3 29.7 5.9 5.5 33.1 23.9 27.6 36.6 25.0 28.6 24.0 14.2 47.4 27.0 39.7 14.6 33.4 9.0 4.4 61.0 33.1 35.5 17.4 56.1 182.0 319.1 42.4 66.2 56.5 198.6 50.3 113.4 94.5 193.9 59.0 0.3 139.5 155.1 39.0 27.0 80.9 144.0 53.6 5.2 70.4 111.6 72.9 82.0 149.3 43.0 20.5 87.1 37.1 127.3 38.0 113.3 189.4 131.4 54.0 26.0 84.2 25.1 115.1 63.8 264.1 5.7 123.4 338.1 197.2 34.5 85.3 23.7 213.7 289.8 67.0 28.8 111.5 58.4 78.7 42.6 298.6 126.7 169.3 28.2 94.9 6.3 3.1 177.5 53.2 40.5 80.5 9.4 1.4 1.1 10.3 0.8 14.0 0.3 0.3 7.2 1.8 0.4 0.4 5.2 3.2 0.3 0.8 5.8 0.2 2.2 44.8 52.5 19.3 71.7 70.1 45.4 33.8 25.4 32.3 24.0 39.7 35.5 44.2 3.2 1.5 8.1 1.2 10.3 13.7 24.6 9.1 7.0 7.6 9.1 5.1 2.8 11.1 9.2 4.2 1.0 4.5 1.4 1.9 87.1 16.9 8.4 44.0 43.2 40.7 4.8 15.7 43.4 2.8 56.1 11.7 18.4 10.8 49.4 20.7 0.0 1.7 42.1 13.0 2.4 40.7 1.8 8.9 41.6 50.1 6.1 8.8 2.8 2.4 13.4 1.0 5.0 1.0 64.5 0.6 41.0 4.0 16.9 0.6 6.3 5.2 4.5 19.7 10.8 43.4 6.5 26.7 20.1 7.2 0.8 10.4 8.1 3.9 7.5 DCAF15 "C19orf72, MGC99481" ENSG00000132017 "DDB1 and CUL4 associated factor 15" Q66K64 19 13952492-13961449 "Predicted intracellular proteins" "Immunity, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068351 Approved Vesicles,Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 12: NES - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Mitochondria Vesicles "HPA068351: AB_2685977" "unprognostic (6.91e-2)" "unprognostic (6.55e-3)" "unprognostic (3.03e-2)" "unprognostic (5.18e-3)" "unprognostic (1.95e-1)" "unprognostic (1.89e-2)" "unprognostic (1.83e-3)" "unprognostic (9.72e-2)" "unprognostic (8.03e-2)" "unprognostic (1.21e-1)" "prognostic favorable (7.97e-4)" "unprognostic (1.98e-2)" "prognostic unfavorable (1.34e-5)" "unprognostic (7.97e-3)" "unprognostic (1.26e-1)" "unprognostic (1.07e-1)" "unprognostic (1.59e-1)" 17.6 10.7 5.9 10.3 6.0 20.5 18.1 7.1 7.9 18.7 4.7 18.1 6.9 17.0 4.3 24.0 16.7 4.5 18.6 6.0 5.6 16.2 13.9 18.6 13.5 5.6 5.2 15.5 13.7 7.1 16.5 7.3 5.2 17.0 5.2 3.6 16.1 5.3 22.9 30.2 23.4 5.1 4.9 33.4 14.0 44.7 5.6 14.6 17.0 8.6 10.8 15.6 21.6 5.4 18.9 11.5 29.5 16.2 3.1 4.5 13.5 12.7 8.8 26.1 25.9 20.4 7.9 17.3 14.4 12.3 15.4 16.7 18.9 12.0 9.2 21.0 33.8 21.3 21.0 21.4 6.5 17.8 30.2 5.9 10.9 19.3 8.6 9.4 13.1 27.4 22.9 24.8 11.6 28.7 32.0 33.0 35.2 12.7 17.8 29.2 10.4 11.8 14.1 14.3 18.8 19.3 11.4 8.1 10.7 12.1 10.5 22.7 9.2 17.8 13.1 28.3 24.1 17.4 20.7 18.3 11.4 25.8 15.6 0.2 0.3 0.9 0.3 0.3 0.2 0.3 0.2 0.3 0.2 0.4 0.1 0.3 0.6 0.1 0.2 0.4 0.6 0.2 5.9 6.0 7.1 7.9 6.0 5.6 5.6 5.2 5.2 4.9 5.6 5.4 19.5 0.0 0.0 6.8 19.7 4.8 10.5 6.9 8.6 17.3 8.9 10.7 2.9 10.0 3.8 9.2 8.4 13.7 24.4 9.6 1.9 11.0 5.0 7.0 7.8 10.9 7.7 9.4 5.2 10.3 15.1 7.5 13.7 7.0 1.3 15.0 7.1 3.4 15.7 15.2 3.4 5.7 4.1 8.1 7.0 9.5 18.3 14.3 1.8 8.4 13.8 9.2 16.5 7.1 5.5 9.9 9.6 12.0 18.3 6.4 4.5 4.7 3.9 13.9 6.6 6.0 7.9 35.6 19.9 10.0 9.8 13.8 21.2 10.4 7.9 8.9 DCAF6 "IQWD1, PC326" ENSG00000143164 "DDB1 and CUL4 associated factor 6" Q58WW2 1 167935783-168075843 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 641.3;tongue: 470.8" "Cell type enhanced" "Detected in all" "Early spermatids: 438.6;Excitatory neurons: 243.8;Late spermatids: 700.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054305 Supported "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Focal adhesion sites" "HPA054305: AB_2682444" "unprognostic (1.54e-1)" "unprognostic (2.11e-1)" "unprognostic (1.42e-1)" "unprognostic (2.31e-1)" "unprognostic (2.20e-1)" "unprognostic (1.19e-1)" "unprognostic (5.42e-2)" "unprognostic (1.81e-1)" "unprognostic (1.51e-1)" "unprognostic (2.12e-1)" "unprognostic (1.74e-1)" "unprognostic (3.20e-2)" "unprognostic (9.21e-2)" "unprognostic (7.06e-2)" "unprognostic (6.00e-2)" "unprognostic (1.04e-1)" "unprognostic (1.49e-1)" 29.1 45.9 12.8 16.2 17.5 24.6 29.3 9.3 22.4 32.9 22.1 36.8 21.7 24.7 19.5 29.7 25.6 27.5 129.9 20.5 7.0 28.6 95.1 25.4 17.7 5.6 8.8 25.3 20.9 34.5 19.9 27.3 5.8 35.4 29.3 21.3 28.8 25.3 641.3 21.9 21.5 33.8 5.7 18.5 28.2 82.6 12.3 24.4 23.5 470.8 21.4 28.1 20.1 14.0 64.8 30.0 16.4 27.0 52.7 74.3 57.4 64.9 95.3 44.5 65.7 50.4 53.1 52.8 36.9 83.3 21.4 47.4 25.8 47.9 62.4 30.2 27.6 56.5 42.8 36.4 42.4 25.7 26.1 53.2 47.4 42.3 35.0 67.4 49.1 16.9 64.8 42.9 66.3 14.8 28.9 23.3 10.6 36.0 33.1 21.9 34.0 41.7 110.6 30.9 24.2 19.2 51.8 47.0 36.6 33.9 80.8 31.3 70.3 44.6 27.5 44.0 27.3 45.4 39.3 41.3 59.9 21.6 18.6 5.4 5.5 10.4 4.9 7.5 5.2 4.8 3.9 4.3 6.0 3.3 3.5 4.6 5.7 3.7 12.0 3.6 4.8 4.0 12.8 17.5 9.3 22.4 20.5 7.0 5.6 8.8 5.8 5.7 12.3 14.0 22.9 57.7 43.3 81.3 22.5 57.9 30.5 32.1 33.0 14.7 26.7 19.3 216.3 48.6 43.4 25.8 22.9 75.7 19.7 28.1 17.6 33.0 438.6 39.3 24.1 25.3 21.1 111.9 243.8 19.3 32.4 42.7 39.3 35.5 19.6 73.0 23.6 95.4 19.6 5.0 90.0 27.9 26.4 44.0 38.3 700.1 57.5 23.6 37.4 70.3 113.0 15.9 18.6 108.6 71.0 21.2 26.7 48.5 31.1 35.6 35.7 34.9 52.3 18.4 32.9 29.1 30.6 108.3 64.1 34.6 39.8 81.3 22.2 81.5 33.0 29.0 DCLRE1A "hSNM1, KIAA0086, PSO2, SNM1" ENSG00000198924 "DNA cross-link repair 1A" Q6PJP8 10 113834725-113854383 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036907 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "Nucleoli fibrillar center" "HPA036907: AB_10673626" "unprognostic (1.22e-1)" "unprognostic (7.55e-2)" "unprognostic (4.84e-2)" "unprognostic (3.82e-2)" "unprognostic (1.09e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (5.74e-5)" "unprognostic (1.04e-1)" "unprognostic (1.15e-1)" "unprognostic (2.01e-2)" "unprognostic (2.12e-1)" "unprognostic (1.12e-1)" "unprognostic (3.40e-2)" "unprognostic (4.05e-2)" "unprognostic (2.85e-1)" "unprognostic (3.07e-1)" "unprognostic (6.34e-2)" 2.1 3.8 3.9 3.9 4.2 4.6 5.2 4.2 5.5 4.0 4.1 4.3 4.1 2.9 5.5 3.3 4.1 2.8 4.4 4.2 4.3 6.0 9.8 3.6 5.3 3.8 3.9 5.3 7.4 8.4 2.9 4.2 4.0 5.9 5.2 8.0 5.0 4.0 3.6 3.7 4.0 3.2 3.8 4.0 5.2 4.7 4.1 5.0 5.1 3.3 5.3 3.2 1.9 4.1 15.8 13.0 19.3 19.7 2.5 4.2 11.0 9.4 9.5 12.5 14.3 10.2 21.1 12.2 10.4 4.8 9.7 12.9 18.6 8.2 16.1 24.2 16.0 20.7 8.0 13.1 8.2 21.9 18.8 2.8 9.8 10.5 18.5 8.3 7.7 16.3 24.1 12.9 7.1 9.4 10.6 8.8 9.4 12.5 6.9 6.1 23.0 8.0 8.3 7.3 8.4 13.9 5.4 9.2 13.8 13.2 11.0 10.5 6.8 7.2 14.1 9.8 15.6 14.9 18.2 18.6 10.7 31.5 10.5 1.3 0.3 0.7 2.8 0.2 1.8 0.6 1.2 1.9 1.1 0.3 0.8 1.4 0.1 1.0 0.5 0.4 3.2 1.2 3.9 4.2 4.2 5.5 4.2 4.3 3.8 3.9 4.0 3.8 4.1 4.1 0.9 6.4 4.1 4.9 1.3 0.6 0.6 2.8 0.6 4.2 2.9 1.9 9.6 5.7 3.6 1.8 0.0 3.0 2.0 2.2 7.9 1.9 0.7 2.9 1.8 1.6 3.5 6.5 4.9 1.1 1.8 2.5 1.5 2.0 1.3 3.6 1.8 7.7 3.2 6.7 4.7 2.5 4.1 3.8 0.6 0.5 1.5 10.3 0.0 2.8 3.6 3.9 2.1 8.0 4.1 1.6 2.3 1.5 3.0 1.3 1.6 3.7 5.1 3.9 0.0 1.7 1.2 6.0 5.4 2.5 0.6 0.7 3.1 2.4 3.4 0.7 DCT TYRP2 ENSG00000080166 "Dopachrome tautomerase" P40126 13 94436811-94479682 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Melanin biosynthesis" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "skin 1: 107.4" "Cell type enriched" "Detected in some" 23 "Melanocytes: 3552.1" "Cancer enriched" "Detected in some" 215 "melanoma: 155.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 272 "SK-MEL-30: 257.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA010742, HPA010743, HPA010800, CAB017634" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Vesicles "CAB017634: AB_1130818, HPA010742: , HPA010743: AB_1847519, HPA010800: AB_1847520" "unprognostic (5.99e-2)" "unprognostic (1.67e-2)" "unprognostic (1.54e-2)" "unprognostic (3.17e-2)" "unprognostic (2.45e-2)" "unprognostic (3.35e-2)" "unprognostic (2.15e-2)" "unprognostic (2.81e-2)" "unprognostic (6.07e-2)" "unprognostic (1.81e-1)" "unprognostic (3.64e-3)" "unprognostic (1.06e-2)" "unprognostic (6.18e-5)" "unprognostic (6.97e-2)" "unprognostic (9.87e-2)" "unprognostic (1.22e-3)" "unprognostic (2.42e-1)" 0.4 0.4 0.6 0.0 1.0 0.1 3.0 0.4 0.7 0.2 0.2 0.3 0.0 0.3 0.9 0.0 0.9 0.1 0.1 0.6 0.6 0.2 0.2 0.1 0.0 0.6 0.6 0.4 0.4 0.0 1.6 0.0 0.5 0.3 0.0 0.9 1.5 0.3 0.4 107.4 0.1 0.1 0.6 0.1 0.1 0.6 0.6 0.5 0.2 0.1 0.0 0.2 0.3 0.5 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 257.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.2 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 0.4 0.7 0.6 0.6 0.6 0.6 0.5 0.6 0.6 0.5 0.0 0.0 0.0 23.5 0.0 152.3 0.1 0.0 0.0 1.0 0.3 0.5 0.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.5 0.1 1.2 0.0 0.0 16.1 0.2 0.0 1.4 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.0 25.5 23.8 0.9 0.0 3552.1 1.9 0.0 3.5 0.0 6.6 2.4 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.5 1.0 0.5 0.8 0.0 33.4 0.0 0.9 0.1 0.0 0.0 DECR1 "DECR, SDR18C1" ENSG00000104325 "2,4-dienoyl-CoA reductase 1" Q16698 8 90001405-90053633 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 290.1;liver: 272.3" "Cell type enhanced" "Detected in all" "Distal tubular cells: 399.2;Proximal tubular cells: 485.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 81.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023160, HPA023162, HPA023238" Enhanced Supported Mitochondria,Cytosol No No 120000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA023160: AB_1847585, HPA023162: AB_1847586, HPA023238: AB_1847587" "prognostic unfavorable (1.49e-4)" "unprognostic (5.76e-3)" "unprognostic (8.37e-3)" "unprognostic (6.13e-3)" "unprognostic (2.01e-1)" "unprognostic (4.45e-2)" "unprognostic (1.68e-2)" "unprognostic (8.23e-2)" "unprognostic (1.02e-1)" "unprognostic (1.55e-1)" "unprognostic (9.12e-2)" "unprognostic (1.42e-1)" "prognostic favorable (1.79e-7)" "unprognostic (1.40e-1)" "unprognostic (1.73e-2)" "unprognostic (1.16e-1)" "prognostic favorable (6.06e-4)" 60.2 136.8 12.4 9.6 14.4 24.9 54.4 12.5 14.4 29.4 22.2 65.0 20.2 28.0 14.9 52.6 26.1 7.4 290.1 12.7 13.2 103.5 272.3 34.2 15.0 12.2 13.1 35.5 44.4 13.2 32.6 5.9 12.1 28.6 18.8 8.0 42.8 6.5 121.8 43.3 61.0 9.1 12.5 47.1 44.5 52.3 15.4 10.2 33.0 34.4 13.9 31.1 35.8 12.8 13.1 7.9 19.6 16.1 8.0 17.3 5.2 13.2 12.9 5.9 8.2 2.8 13.4 7.7 5.3 15.1 4.1 6.8 7.7 11.1 11.0 12.6 1.2 18.4 13.6 14.5 11.6 8.7 4.4 12.0 7.0 7.6 10.7 10.1 17.4 16.5 21.3 15.5 20.7 16.3 12.5 7.6 1.5 9.1 24.9 7.4 5.8 13.4 23.4 43.9 1.3 10.6 13.0 81.1 7.7 1.1 10.7 7.4 20.1 11.4 6.2 12.9 6.0 10.5 7.5 12.8 8.6 12.0 10.8 3.9 9.1 6.2 7.1 10.2 7.9 7.4 6.9 8.6 8.8 4.6 8.1 7.8 15.2 3.9 9.3 3.9 9.6 5.8 12.4 14.4 12.5 14.4 12.7 13.2 12.2 13.1 12.1 12.5 15.4 12.8 66.1 76.9 59.4 72.5 52.9 41.3 70.6 180.2 35.3 11.4 51.1 57.4 268.3 82.9 96.4 71.7 2.1 50.2 57.6 119.0 399.2 137.8 165.3 68.2 65.5 60.0 104.8 77.4 27.2 92.5 49.0 60.2 61.2 40.6 50.0 81.3 47.8 244.8 115.1 32.0 55.9 105.9 116.0 95.2 82.7 52.6 85.4 85.1 85.4 29.0 107.1 52.5 74.2 66.9 35.0 87.5 111.6 51.6 67.8 30.3 250.3 485.2 69.0 7.6 72.3 54.5 61.7 157.5 24.6 68.6 41.1 41.0 64.4 135.1 139.6 86.8 DEF6 "IBP, SLAT, SWAP70L" ENSG00000023892 "DEF6 guanine nucleotide exchange factor" Q9H4E7 6 35297818-35321771 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 63.2;lymphoid tissue: 62.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 94.0;Late spermatids: 151.4;NK-cells: 88.6;T-cells: 78.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "JURKAT: 83.3;MOLT-4: 75.5;NB-4: 99.3;REH: 68.8;THP-1: 78.9;U-937: 117.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA038975, HPA038976" Enhanced Enhanced Nucleoplasm Yes NA "Cluster 5: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA038975: AB_10697544, HPA038976: AB_10673409" "prognostic favorable (3.02e-6)" "prognostic favorable (1.08e-4)" "prognostic unfavorable (1.71e-4)" "prognostic favorable (2.37e-4)" "unprognostic (1.93e-1)" "unprognostic (3.63e-3)" "unprognostic (2.24e-1)" "unprognostic (1.53e-2)" "unprognostic (1.64e-1)" "unprognostic (2.12e-1)" "unprognostic (2.14e-1)" "unprognostic (6.21e-3)" "prognostic unfavorable (1.02e-8)" "unprognostic (1.78e-1)" "unprognostic (2.91e-2)" "unprognostic (1.38e-1)" "unprognostic (1.45e-3)" 5.8 3.6 5.9 33.5 5.9 63.2 6.0 6.3 7.2 8.0 7.3 9.8 10.2 2.8 8.5 28.2 4.4 7.2 2.6 5.9 6.6 4.7 5.2 14.7 48.6 8.7 7.0 3.1 21.6 1.3 8.3 7.7 8.0 21.0 7.4 2.2 15.8 4.8 1.7 28.5 30.7 3.5 7.7 62.9 16.3 26.7 8.1 50.2 8.3 1.1 38.1 10.2 16.5 8.8 24.0 0.0 0.8 0.6 0.1 0.3 29.0 2.6 3.6 0.6 0.7 1.5 10.0 28.1 8.3 1.3 0.1 15.5 0.0 19.6 0.4 1.0 1.1 31.7 0.4 12.6 0.7 57.5 40.0 4.5 24.6 0.3 22.0 0.1 0.0 83.3 14.3 65.7 0.1 12.3 75.5 99.3 1.3 3.0 2.8 68.8 0.6 38.4 2.5 17.8 0.4 0.2 2.1 5.8 5.5 1.1 15.9 78.9 3.8 0.3 0.6 0.1 0.3 37.2 37.1 23.3 0.0 117.7 0.2 49.2 39.5 119.7 78.6 29.7 62.4 34.2 63.3 76.8 55.2 31.3 65.1 65.2 69.3 72.9 27.8 36.6 73.1 64.3 5.9 5.9 6.3 7.2 5.9 6.6 8.7 7.0 8.0 7.7 8.1 8.8 1.7 6.4 8.0 1.3 49.2 11.9 16.9 15.0 20.5 2.5 5.4 7.2 0.8 2.8 8.2 5.5 0.0 25.0 52.3 4.2 0.0 0.9 56.3 2.2 0.8 3.1 4.2 6.7 2.0 10.0 17.2 2.2 26.0 3.0 17.7 1.5 2.9 0.9 94.0 3.3 1.0 9.9 2.0 28.0 26.4 151.4 2.8 31.7 7.2 17.8 30.0 0.8 88.6 0.5 0.5 8.0 8.9 1.9 57.9 6.0 3.1 0.3 5.8 1.7 0.0 0.6 1.2 40.0 0.9 20.0 11.8 12.6 78.3 1.0 9.1 13.0 DEFA4 "DEF4, HP-4" ENSG00000164821 "Defensin alpha 4" P12838 8 6935820-6938306 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 58 "bone marrow: 2702.9" "Cell type enhanced" "Detected in some" "Erythroid cells: 3.2;Hepatocytes: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 13 "neutrophil: 13.1" "Lineage enriched" "Detected in many" 13 "granulocytes: 13.1" "Cell line enriched" "Detected in single" 8 "THP-1: 6.8" HPA051266 Enhanced "Secreted to blood" NA NA 98000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "HPA051266: AB_2681414" 0.7 0.1 0.0 0.2 0.0 2702.9 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.3 2.7 14.2 0.6 0.0 0.0 0.0 0.1 0.0 0.7 1.1 0.0 0.0 0.0 0.0 2.3 0.0 0.4 2.0 0.1 0.0 0.0 46.4 0.1 0.1 0.0 8.9 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 35.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 DENND11 "KIAA1147, LCHN" ENSG00000257093 "DENN domain containing 11" A4D1U4 7 141656728-141702166 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 9.2;B-cells: 3.8;Cardiomyocytes: 4.3;dendritic cells: 8.5;Hofbauer cells: 7.6;Plasma cells: 6.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "basophil: 1.7" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.7" "Cell line enhanced" "Detected in many" "HDLM-2: 5.5;HEK 293: 5.3;U-266/70: 7.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029467, HPA061437" Approved Approved "Golgi apparatus" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" "HPA029467: AB_10602915, HPA061437: AB_2684517" "unprognostic (1.27e-1)" "unprognostic (5.68e-2)" "unprognostic (7.05e-2)" "unprognostic (1.77e-1)" "unprognostic (4.44e-2)" "prognostic favorable (6.24e-4)" "unprognostic (6.49e-2)" "unprognostic (3.63e-2)" "unprognostic (3.02e-2)" "unprognostic (4.27e-1)" "unprognostic (7.62e-2)" "unprognostic (3.75e-2)" "prognostic favorable (8.01e-4)" "unprognostic (1.76e-1)" "unprognostic (2.09e-1)" "unprognostic (1.91e-3)" "unprognostic (1.78e-1)" 8.7 5.9 7.1 1.0 8.0 0.9 9.6 5.4 10.2 8.0 4.3 11.0 3.6 7.0 0.5 12.5 8.1 0.5 6.8 10.7 5.3 8.8 14.7 13.3 1.6 9.0 7.7 7.5 17.4 1.0 11.8 0.3 8.6 9.0 1.5 2.8 20.6 0.7 5.7 8.7 14.4 0.6 7.0 14.2 17.8 1.4 6.9 0.6 12.4 0.5 1.2 8.5 11.3 10.6 1.9 1.5 0.9 1.2 0.5 0.2 0.3 0.4 0.3 0.3 0.3 1.9 1.3 0.1 3.1 0.3 0.8 0.6 1.0 0.8 0.7 5.5 5.3 0.9 0.8 0.3 0.1 1.7 0.3 0.2 0.7 0.2 0.3 0.8 1.3 1.0 0.0 0.3 0.2 0.7 1.5 1.2 1.5 2.1 1.0 3.6 0.2 1.7 0.6 1.0 1.4 2.7 1.2 2.1 0.2 0.5 0.8 0.2 4.3 0.2 1.0 0.4 2.2 7.5 1.8 2.4 0.6 2.3 0.3 1.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 7.1 8.0 5.4 10.2 10.7 5.3 9.0 7.7 8.6 7.0 6.9 10.6 9.2 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.4 8.5 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 DENND2A "FAM31D, KIAA1277" ENSG00000146966 "DENN domain containing 2A" Q9ULE3 7 140518420-140673993 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 114.9;Horizontal cells: 89.2;Oligodendrocyte precursor cells: 72.4;Paneth cells: 69.5" "Cancer enriched" "Detected in all" 6 "glioma: 28.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 57.7;BJ hTERT+: 60.8;PC-3: 29.1;RPTEC TERT1: 72.7;U-2197: 32.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (5.02e-2)" "unprognostic (1.14e-1)" "prognostic favorable (9.35e-4)" "unprognostic (1.78e-1)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.95e-2)" "unprognostic (1.43e-1)" "unprognostic (3.10e-2)" "unprognostic (1.05e-1)" "unprognostic (1.28e-1)" "unprognostic (1.57e-3)" "unprognostic (2.09e-2)" "prognostic unfavorable (3.05e-6)" "unprognostic (1.03e-1)" "unprognostic (2.41e-1)" "unprognostic (3.54e-2)" "unprognostic (2.38e-3)" 15.4 3.9 28.9 2.5 32.5 0.6 11.0 23.5 25.8 25.0 46.9 12.0 3.9 26.2 5.1 9.6 30.7 11.1 16.1 25.2 28.8 14.5 3.1 17.6 2.3 43.7 39.7 21.7 2.2 5.0 26.3 15.5 33.7 11.4 5.6 11.5 2.6 5.4 7.1 3.9 8.9 16.0 34.6 12.2 6.6 2.1 32.1 0.8 3.7 7.8 1.8 12.1 11.4 26.2 0.2 0.9 57.7 0.5 6.2 1.1 12.4 2.2 60.8 9.5 15.3 0.0 0.1 0.1 0.4 0.6 10.2 0.2 11.0 0.8 17.8 0.0 1.0 0.0 0.2 0.0 1.6 0.2 0.1 2.8 0.6 13.9 2.1 24.9 0.0 0.1 0.1 0.2 0.0 0.2 0.1 0.3 12.3 0.1 29.1 2.1 3.7 0.2 72.7 0.1 4.6 14.5 0.0 0.0 0.0 16.7 0.1 0.6 0.0 10.9 2.2 32.1 5.9 0.3 0.0 0.1 0.9 0.1 3.9 1.0 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.1 1.2 0.3 0.1 0.2 0.1 0.0 28.9 32.5 23.5 25.8 25.2 28.8 43.7 39.7 33.7 34.6 32.1 26.2 13.8 0.0 3.0 34.9 0.5 1.3 1.9 0.1 0.6 7.4 1.9 1.0 4.3 0.0 1.3 0.0 8.4 1.0 0.3 114.9 7.9 0.0 1.4 0.4 8.3 4.6 9.6 0.0 10.0 0.0 4.9 14.8 1.1 0.3 11.4 22.4 9.7 0.7 2.4 89.2 23.2 37.1 0.0 0.3 2.1 1.0 18.6 0.6 1.8 32.8 0.1 16.2 0.0 72.4 42.3 0.1 69.5 10.5 0.0 2.2 3.8 0.1 1.0 10.5 13.1 11.8 11.3 0.1 0.9 0.2 0.4 0.4 1.1 0.2 42.7 1.2 DERA "CGI-26, DEOC" ENSG00000023697 "Deoxyribose-phosphate aldolase" Q9Y315 12 15911302-16037381 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 104.6" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 152.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055897 Supported Nucleoplasm NA NA 320000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA055897: AB_2682963" "unprognostic (3.05e-1)" "unprognostic (1.26e-1)" "unprognostic (1.06e-2)" "unprognostic (7.26e-2)" "unprognostic (8.12e-2)" "unprognostic (7.74e-2)" "unprognostic (1.36e-1)" "unprognostic (1.47e-2)" "unprognostic (2.76e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (1.32e-4)" "unprognostic (2.13e-1)" "unprognostic (1.09e-1)" "unprognostic (8.74e-2)" "unprognostic (2.17e-2)" "prognostic favorable (3.64e-5)" "unprognostic (3.66e-2)" 21.1 16.3 13.7 17.3 16.0 17.6 21.1 15.8 17.1 16.7 21.5 39.9 41.1 16.2 27.0 30.4 15.0 20.3 18.1 13.4 16.0 74.1 104.6 25.0 20.3 16.5 14.8 6.8 27.2 15.6 12.1 20.7 16.4 13.5 42.1 28.1 17.9 14.1 27.8 25.3 54.0 20.4 15.4 17.0 21.7 9.7 15.2 19.8 27.9 29.6 22.7 18.3 18.2 17.1 63.6 51.4 40.0 36.6 27.1 60.3 80.6 36.6 35.2 48.7 63.2 63.9 118.1 44.3 31.3 47.2 44.1 43.8 43.4 47.6 84.7 71.3 25.6 37.6 24.1 60.6 38.7 40.7 25.2 40.8 54.9 40.9 81.0 42.2 71.6 36.2 5.3 13.1 92.1 24.1 30.6 34.5 86.8 37.3 25.6 45.8 85.5 26.8 125.0 23.2 29.5 49.9 69.3 23.4 75.4 158.2 124.5 50.6 66.3 53.6 33.5 24.4 39.0 13.6 21.4 76.9 66.6 41.1 39.6 15.2 58.4 36.2 16.6 68.4 18.2 29.4 17.7 17.7 74.9 29.9 19.3 15.5 15.8 46.0 76.4 40.4 38.1 41.9 13.7 16.0 15.8 17.1 13.4 16.0 16.5 14.8 16.4 15.4 15.2 17.1 37.2 44.8 28.4 20.2 19.4 29.3 31.6 55.3 21.6 4.8 22.4 18.8 13.5 27.1 43.1 12.9 14.6 65.7 22.1 51.6 109.5 64.3 55.8 27.8 32.3 28.3 26.5 28.2 8.6 59.3 69.9 23.9 14.3 52.9 8.8 30.6 36.4 52.2 61.0 3.3 5.9 44.7 54.9 46.7 26.4 6.7 24.5 44.8 72.9 30.9 47.4 29.8 14.4 28.6 18.9 74.6 49.6 30.5 30.7 19.1 140.0 152.3 27.3 29.9 6.6 17.4 27.5 8.5 16.7 35.5 25.9 71.3 13.9 49.0 42.9 34.0 DHCR24 "DCE, KIAA0018, seladin-1" ENSG00000116133 "24-dehydrocholesterol reductase" Q15392 1 54849627-54887195 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 1129.5;liver: 623.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 298.1;Alveolar cells type 2: 682.3;Hepatocytes: 1091.4;Theca cells: 442.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1031.9" "Low region specificity" "Detected in all" "HPA017981, CAB037247, HPA063005" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "CAB037247: AB_796187, HPA017981: AB_2732422, HPA063005: AB_2684919" "unprognostic (2.88e-1)" "unprognostic (1.80e-2)" "unprognostic (4.99e-3)" "prognostic unfavorable (1.05e-5)" "unprognostic (1.69e-1)" "unprognostic (2.61e-1)" "unprognostic (1.54e-2)" "unprognostic (1.85e-1)" "unprognostic (1.68e-1)" "unprognostic (1.86e-1)" "unprognostic (6.18e-3)" "unprognostic (3.35e-1)" "unprognostic (7.82e-3)" "unprognostic (5.48e-2)" "unprognostic (1.83e-1)" "unprognostic (1.70e-1)" "unprognostic (3.97e-2)" 58.3 1129.5 35.7 19.8 58.5 1.6 104.8 125.3 73.0 54.9 30.4 55.6 62.2 13.1 1.6 296.1 60.4 42.2 18.0 55.9 63.9 48.6 623.5 215.9 9.4 216.2 91.3 28.5 30.5 157.9 17.0 21.6 158.9 128.6 40.5 15.8 136.2 8.3 197.7 247.6 29.6 12.6 129.3 134.1 98.9 74.2 87.9 10.1 15.4 11.1 33.9 13.5 103.9 280.7 342.1 58.5 210.6 257.1 1031.9 219.0 50.5 94.8 160.3 130.7 268.6 341.6 210.2 55.3 191.5 82.4 427.4 319.2 250.5 501.3 118.3 8.3 159.6 303.3 131.8 421.7 168.9 126.7 68.2 161.0 429.0 397.6 74.7 66.7 67.2 124.5 224.7 0.2 50.2 143.5 25.8 111.4 592.0 90.7 164.2 0.3 54.2 166.3 735.3 257.1 144.5 53.2 185.0 337.5 123.1 221.6 441.5 143.3 62.2 45.3 130.0 66.1 183.9 22.7 55.0 91.2 32.8 215.3 60.4 5.1 1.5 0.7 6.0 1.8 0.3 3.7 2.5 2.6 5.2 1.3 2.2 2.9 0.0 2.7 0.7 3.0 0.4 4.4 35.7 58.5 125.3 73.0 55.9 63.9 216.2 91.3 158.9 129.3 87.9 280.7 6.2 298.1 682.3 12.4 13.3 31.5 17.3 150.6 79.1 9.7 87.9 33.1 15.3 145.8 205.2 68.0 0.0 35.2 6.4 133.3 3.9 55.3 22.9 14.5 5.8 13.5 24.0 71.6 14.5 76.5 34.4 17.5 38.7 44.7 32.2 26.4 111.0 1091.4 28.0 5.0 8.7 39.2 69.2 68.9 8.2 77.2 14.0 9.4 14.2 1.9 6.8 3.6 2.1 5.5 62.6 48.6 27.7 7.9 1.8 52.4 22.6 14.4 136.3 6.4 0.0 1.5 23.2 5.4 14.7 145.4 80.4 30.6 10.6 442.4 35.2 45.2 DHFR ENSG00000228716 "Dihydrofolate reductase" P00374 5 80626226-80654983 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Methotrexate resistance, One-carbon metabolism" "Oxidoreductase, RNA-binding" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 145.8;Spermatocytes: 132.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037129, HPA051465" Uncertain Approved Mitochondria NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "CAB037129: AB_439683, HPA051465: AB_2681494" "unprognostic (1.44e-2)" "unprognostic (1.03e-2)" "unprognostic (2.24e-3)" "unprognostic (2.91e-3)" "unprognostic (3.27e-1)" "unprognostic (1.32e-1)" "unprognostic (2.83e-2)" "unprognostic (2.35e-2)" "unprognostic (2.02e-2)" "unprognostic (4.19e-3)" "unprognostic (1.83e-2)" "unprognostic (2.55e-1)" "unprognostic (1.15e-2)" "unprognostic (1.82e-2)" "unprognostic (2.49e-1)" "unprognostic (1.57e-1)" "unprognostic (1.09e-1)" 25.2 5.3 15.3 20.7 16.5 54.3 12.0 15.8 21.9 8.0 13.3 21.4 24.5 8.6 7.0 14.1 7.4 8.5 7.2 13.8 15.5 21.3 60.1 7.5 41.5 16.6 16.6 6.6 3.2 9.1 6.3 14.4 16.6 8.9 25.3 10.3 6.8 9.5 19.6 9.8 25.1 12.0 16.5 10.3 12.2 18.5 15.8 60.7 8.2 25.8 39.5 10.3 5.7 17.7 98.1 66.6 164.8 122.7 30.7 32.0 60.6 76.5 58.1 130.2 149.0 63.8 114.6 196.9 32.5 44.6 106.0 67.0 214.4 98.6 208.5 88.2 132.1 94.8 104.5 59.5 6.6 111.7 40.3 22.3 9.9 116.9 13.0 22.2 63.9 142.0 108.3 146.7 133.5 98.2 276.5 44.9 83.6 48.3 38.5 176.7 323.3 194.1 75.1 61.5 134.3 93.7 107.9 49.9 54.6 83.5 98.5 108.6 38.5 41.0 62.0 116.0 148.3 68.2 146.6 210.3 91.5 222.1 107.7 0.2 0.3 0.2 0.5 0.6 0.2 0.5 0.6 0.8 0.5 0.5 0.5 0.6 0.8 0.5 0.5 0.8 0.9 0.6 15.3 16.5 15.8 21.9 13.8 15.5 16.6 16.6 16.6 16.5 15.8 17.7 4.1 6.4 11.7 4.9 21.4 6.9 6.5 6.0 4.0 3.5 8.9 8.9 13.0 4.3 6.1 14.7 2.1 35.2 7.4 19.3 9.8 7.4 7.4 10.8 7.7 7.7 4.9 145.8 7.3 3.7 47.3 12.0 11.7 8.0 2.5 22.0 10.0 48.3 44.7 3.3 7.2 19.1 4.1 18.9 4.4 6.4 14.0 12.8 0.0 4.7 7.1 14.5 13.4 3.5 6.0 4.7 10.3 16.1 60.9 2.9 26.6 40.0 6.9 3.2 13.1 9.0 12.5 132.2 49.8 21.2 5.5 13.3 11.8 12.3 38.1 12.1 DKK3 "REIC, RIG" ENSG00000050165 "Dickkopf WNT signaling pathway inhibitor 3" Q9UBP4 11 11956207-12009769 "Plasma proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1224.0" "Group enriched" "Detected in many" 7 "Cardiomyocytes: 884.3;Muller glia cells: 1960.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 6.2;memory CD8 T-cell: 3.8" "Lineage enriched" "Detected in single" 62 "T-cells: 6.2" "Cell line enhanced" "Detected in many" "BJ: 418.9;BJ hTERT+: 643.0;fHDF/TERT166: 614.4;hTERT-RPE1: 370.2;TIME: 349.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011868, CAB024949" Approved Supported "Nuclear bodies,Vesicles,Cytosol" "Secreted in other tissues" No No 18000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Nuclear bodies, Cytosol" "CAB024949: , HPA011868: AB_1847716" "unprognostic (4.24e-2)" "unprognostic (6.40e-2)" "unprognostic (1.96e-1)" "unprognostic (7.84e-2)" "unprognostic (3.06e-3)" "unprognostic (6.58e-3)" "unprognostic (1.14e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-3)" "unprognostic (5.28e-2)" "unprognostic (4.51e-2)" "unprognostic (3.87e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (7.41e-3)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.02e-3)" 31.2 79.1 110.7 10.0 183.6 0.2 26.0 12.6 135.2 89.7 104.8 53.2 14.6 47.0 16.7 29.7 23.0 67.0 1224.0 147.7 80.2 17.0 5.6 123.7 8.5 95.1 54.3 38.1 18.2 34.2 38.2 25.0 46.8 59.4 13.0 204.1 30.9 78.1 7.8 29.7 24.6 43.1 83.9 33.2 31.7 30.9 99.9 4.7 16.4 18.8 5.4 40.9 48.3 121.6 1.5 13.1 18.1 0.1 15.3 29.7 0.6 418.9 643.0 182.4 205.5 9.6 3.2 0.0 44.8 614.4 96.8 64.4 1.5 181.9 69.5 0.1 0.5 0.0 1.7 0.0 113.6 0.0 0.3 45.3 60.0 61.9 151.3 370.2 195.3 0.0 0.2 0.4 256.4 0.0 0.1 0.4 8.6 0.0 0.5 0.1 1.2 0.1 62.5 0.6 0.5 53.2 2.0 0.0 0.2 47.9 0.2 0.5 349.7 107.5 82.8 11.2 110.3 0.1 0.0 0.3 18.1 0.0 103.5 0.0 0.0 0.0 0.5 0.0 6.2 0.0 0.6 3.8 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 110.7 183.6 12.6 135.2 147.7 80.2 95.1 54.3 46.8 83.9 99.9 121.6 5.8 3.2 3.0 94.3 0.1 45.6 59.5 70.3 93.4 31.6 3.2 103.2 884.3 0.0 12.8 0.0 12.5 0.5 0.4 0.0 0.0 0.8 104.3 0.7 8.4 32.9 1.8 0.0 90.4 0.2 0.8 106.1 7.1 0.6 1.3 17.0 66.8 0.4 20.4 13.5 83.7 0.1 0.0 1.3 12.5 88.5 20.5 1.4 64.0 38.4 0.0 1960.4 0.0 27.6 14.7 1.1 0.1 57.6 1.7 32.8 0.0 0.2 2.9 67.5 190.7 12.7 83.4 1.2 3.2 5.8 14.8 0.8 4.1 0.5 0.3 3.0 DLD "DLDH, E3, GCSL, LAD, OGDC-E3" ENSG00000091140 "Dihydrolipoamide dehydrogenase" P09622 7 107891162-107931730 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 357.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 356.2;Distal tubular cells: 226.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044849 Supported Approved Nucleoplasm,Mitochondria NA NA 10000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA044849: AB_2679111" "unprognostic (2.01e-3)" "unprognostic (2.26e-1)" "unprognostic (1.27e-2)" "unprognostic (9.27e-2)" "unprognostic (5.01e-3)" "unprognostic (9.27e-2)" "unprognostic (2.48e-1)" "unprognostic (2.83e-2)" "unprognostic (1.19e-1)" "unprognostic (3.95e-2)" "unprognostic (9.43e-2)" "unprognostic (7.35e-2)" "prognostic favorable (7.58e-9)" "unprognostic (4.08e-2)" "unprognostic (1.88e-1)" "unprognostic (4.45e-3)" "unprognostic (1.18e-1)" 108.7 98.9 22.7 42.1 23.7 54.0 49.0 27.1 29.1 36.3 35.6 109.0 81.8 45.3 21.2 94.1 34.3 48.5 264.1 23.1 29.5 153.3 112.8 39.3 50.1 27.1 27.4 30.0 49.2 136.7 27.8 43.1 26.6 45.7 99.3 35.0 50.2 50.3 295.0 38.9 71.9 67.7 24.9 38.4 80.5 31.3 25.7 43.2 64.2 357.0 67.5 66.1 32.7 23.4 171.4 134.5 74.8 127.9 104.6 91.4 88.4 96.5 80.8 110.6 86.2 159.5 95.5 165.9 159.6 103.0 177.7 110.9 150.2 135.8 166.1 111.1 88.4 116.9 175.6 116.7 80.3 194.7 116.0 104.8 97.6 116.4 63.4 72.3 134.0 137.0 298.5 119.7 121.8 188.1 161.8 138.9 87.4 206.0 98.2 113.1 117.8 225.9 151.8 250.8 92.3 99.9 156.3 262.1 143.9 149.9 100.5 165.8 87.9 120.7 97.3 238.1 149.4 89.3 187.1 114.6 115.0 204.1 130.2 132.7 63.9 136.0 46.9 81.6 49.4 37.8 46.8 46.8 87.2 38.5 47.9 50.5 39.9 68.1 116.9 29.9 49.0 64.2 22.7 23.7 27.1 29.1 23.1 29.5 27.1 27.4 26.6 24.9 25.7 23.4 26.7 28.9 20.7 14.7 26.3 31.4 42.7 124.7 31.3 47.1 24.0 19.2 356.2 51.5 70.5 79.1 22.9 110.2 27.3 56.1 226.9 69.3 10.2 27.6 26.2 32.2 30.6 53.9 23.9 55.9 62.7 36.3 36.7 28.0 26.6 35.3 26.0 86.8 69.2 21.9 25.3 44.1 114.0 41.0 26.5 7.3 23.3 37.5 37.4 15.9 62.2 36.0 38.1 21.1 16.7 42.6 51.4 42.2 30.7 24.3 60.0 178.9 55.5 45.5 26.3 28.4 44.8 55.2 51.5 48.0 32.4 108.4 29.5 73.7 78.7 39.2 DLG3 "KIAA1232, MRX90, NE-Dlg, NEDLG, PPP1R82, SAP-102, SAP102" ENSG00000082458 "Discs large MAGUK scaffold protein 3" Q92796 X 70444835-70505490 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 55.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001733, HPA078130" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 35: T-regs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 12: NES - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Nucleoli" "HPA001733: AB_1078675, HPA078130: AB_2686879" "prognostic unfavorable (1.69e-4)" "unprognostic (1.87e-3)" "unprognostic (1.37e-1)" "unprognostic (2.77e-1)" "unprognostic (4.65e-2)" "unprognostic (3.44e-2)" "unprognostic (3.64e-1)" "unprognostic (1.20e-2)" "unprognostic (7.79e-2)" "unprognostic (7.92e-2)" "unprognostic (1.26e-1)" "unprognostic (5.98e-2)" "prognostic favorable (1.72e-10)" "unprognostic (3.36e-2)" "unprognostic (5.45e-2)" "unprognostic (1.51e-2)" "unprognostic (1.97e-3)" 3.6 3.7 14.6 4.9 16.0 0.6 11.7 8.3 19.2 10.9 9.5 18.6 13.4 8.3 25.5 20.4 19.1 10.7 7.9 19.7 10.1 16.7 1.7 8.8 3.6 6.1 9.5 11.9 35.2 36.3 11.6 5.9 9.0 11.4 18.9 10.5 23.2 10.8 1.2 11.8 16.0 9.0 6.6 20.0 17.3 1.8 10.9 4.6 15.3 2.0 7.4 10.3 12.2 12.9 6.9 3.1 18.9 8.1 4.8 5.8 13.2 4.0 4.5 2.2 2.2 19.4 15.8 0.0 9.1 4.0 1.6 14.5 37.1 8.8 1.4 8.1 11.3 0.0 17.4 10.7 9.4 0.2 2.6 6.1 5.7 2.8 6.1 19.4 0.8 12.9 3.7 26.5 2.1 24.1 15.8 0.1 31.9 55.5 22.3 14.7 9.3 3.0 12.8 20.7 8.9 0.5 3.2 36.9 7.3 15.6 19.4 0.0 1.5 2.5 2.5 2.4 3.0 17.3 13.9 8.4 3.7 0.1 3.7 0.0 0.0 0.0 0.5 0.0 0.5 0.1 0.4 0.7 0.0 0.0 0.3 0.4 0.0 0.5 0.0 0.0 0.7 0.1 14.6 16.0 8.3 19.2 19.7 10.1 6.1 9.5 9.0 6.6 10.9 12.9 2.2 19.2 22.5 4.6 1.7 0.8 5.5 10.8 7.4 20.2 16.8 10.4 17.2 22.8 17.5 9.2 0.0 6.3 7.0 36.7 11.7 15.0 0.0 27.7 5.7 1.8 25.7 0.8 24.8 24.9 2.6 7.4 17.9 15.8 1.3 6.4 3.6 0.3 0.6 5.0 24.5 23.7 4.1 0.3 1.2 0.3 1.5 1.3 1.8 7.5 1.8 11.6 3.1 20.1 5.4 21.6 19.3 6.4 5.7 13.9 26.1 6.0 31.5 6.3 6.6 4.0 11.1 2.9 2.9 13.1 2.0 1.6 8.1 2.5 21.4 10.5 DMD "BMD, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, MRX85" ENSG00000198947 Dystrophin P11532 X 31097677-33339609 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transporters" Actin-binding "Cancer-related genes, Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 452.8;Excitatory neurons: 1275.8;Inhibitory neurons: 719.8;Oligodendrocyte precursor cells: 1161.6;Oligodendrocytes: 610.2;Rod photoreceptor cells: 375.9" "Cancer enhanced" "Detected in many" "testis cancer: 8.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 4.3" "Group enriched" "Detected in many" 7 "B-cells: 1.1;granulocytes: 4.3" "Cell line enhanced" "Detected in many" "AF22: 27.9;Hep G2: 30.3;RH-30: 25.0;SuSa: 27.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000119, HPA002725, HPA023885" Enhanced NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB000119: , HPA002725: AB_1078714, HPA023885: AB_1847931" "unprognostic (3.91e-3)" "unprognostic (2.29e-1)" "unprognostic (1.83e-2)" "unprognostic (1.09e-1)" "unprognostic (2.17e-1)" "unprognostic (7.58e-2)" "unprognostic (3.41e-1)" "unprognostic (2.60e-4)" "unprognostic (6.98e-2)" "unprognostic (1.25e-1)" "unprognostic (5.84e-3)" "unprognostic (2.38e-1)" "unprognostic (1.15e-2)" "unprognostic (8.76e-3)" "unprognostic (1.82e-1)" "unprognostic (9.83e-2)" "unprognostic (1.51e-2)" 16.3 14.7 11.8 5.3 12.5 0.6 16.8 0.2 14.2 7.1 7.1 38.0 5.4 18.1 11.2 9.1 16.8 21.5 37.8 15.5 0.5 5.4 50.0 7.2 4.7 1.1 0.6 13.9 52.9 4.3 4.4 15.1 0.4 13.4 8.4 80.0 30.2 30.7 73.4 11.5 9.4 22.0 0.0 2.3 15.5 8.3 4.8 3.3 7.3 67.4 6.4 21.1 7.2 9.9 0.3 0.2 27.9 0.3 0.3 0.3 7.6 6.1 0.6 2.8 3.1 13.3 0.6 0.4 0.2 12.5 2.3 8.5 10.5 15.0 4.2 7.4 8.6 3.3 10.5 30.3 14.7 1.2 3.7 3.3 9.5 4.6 17.1 15.3 6.1 2.0 2.9 0.4 8.3 0.5 4.4 0.6 13.3 0.1 9.8 0.3 25.0 0.1 0.3 3.3 0.5 8.5 0.1 2.3 2.8 27.7 2.2 0.1 1.6 0.3 0.5 1.1 4.6 0.4 23.8 0.6 1.0 2.3 14.4 0.8 0.1 2.0 0.1 0.1 0.1 1.1 0.1 0.1 0.3 0.9 0.1 0.1 4.3 0.1 0.1 0.4 0.2 0.1 11.8 12.5 0.2 14.2 15.5 0.5 1.1 0.6 0.4 0.0 4.8 9.9 8.5 28.9 25.3 164.9 6.7 20.1 7.0 6.3 3.4 78.0 26.5 50.0 452.8 7.2 15.0 3.7 308.6 33.7 0.7 0.8 3.9 3.8 22.4 22.5 1.4 9.9 8.4 0.0 1275.8 12.3 9.5 26.1 3.6 5.6 1.3 37.9 6.1 49.8 4.2 11.8 719.8 1.3 6.1 4.8 5.4 20.5 89.2 3.5 19.6 94.6 6.7 54.9 0.0 1161.6 610.2 6.0 0.1 118.8 0.2 3.6 3.6 2.1 60.4 375.9 118.3 95.2 50.3 4.0 8.8 1.8 11.5 5.1 1.0 33.1 4.2 4.8 DMPK "DM, DM1, DM1PK, DMK, MDPK, MT-PK" ENSG00000104936 "DM1 protein kinase" Q09013 19 45769709-45782552 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 44.1;Sertoli cells: 59.2;Smooth muscle cells: 34.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 85.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 8.7" "HPA007164, HPA008905" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol Vesicles "HPA007164: AB_1078687, HPA008905: AB_1078685" "unprognostic (7.44e-2)" "unprognostic (2.66e-1)" "unprognostic (1.76e-3)" "unprognostic (2.61e-3)" "unprognostic (1.29e-1)" "unprognostic (5.46e-2)" "unprognostic (8.67e-2)" "unprognostic (1.50e-1)" "unprognostic (1.31e-1)" "unprognostic (1.67e-1)" "prognostic favorable (9.39e-5)" "unprognostic (1.93e-1)" "unprognostic (1.60e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-1)" "unprognostic (3.03e-2)" "unprognostic (4.24e-3)" 24.2 68.3 22.1 17.5 24.0 3.0 19.1 22.2 33.1 42.8 25.6 121.5 15.8 92.7 5.3 33.4 61.2 13.9 171.3 21.8 21.6 20.3 8.8 29.8 5.2 24.0 23.8 31.1 34.3 2.9 37.9 8.8 22.3 56.4 4.8 4.1 18.6 37.6 173.6 12.3 34.6 59.9 21.9 17.8 51.7 13.2 23.8 4.2 21.7 143.2 1.3 69.1 34.3 21.3 11.7 16.7 13.5 10.7 13.4 12.9 10.5 26.1 22.2 10.5 8.8 2.2 6.6 2.9 2.8 32.9 9.2 15.1 3.0 1.5 2.2 12.4 16.6 0.8 22.6 1.4 12.6 0.1 5.4 22.8 8.0 6.4 1.7 24.2 3.6 2.1 8.6 8.0 15.4 13.7 1.6 3.8 8.8 4.8 3.3 5.0 85.1 6.4 4.7 11.5 10.2 13.5 13.6 27.6 9.3 4.8 28.6 5.5 8.4 9.2 10.4 8.3 15.0 16.8 11.5 2.9 9.5 1.3 13.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.1 24.0 22.2 33.1 21.8 21.6 24.0 23.8 22.3 21.9 23.8 21.3 10.5 0.0 2.2 44.1 3.7 8.0 8.1 3.8 5.7 5.7 9.6 9.9 3.7 4.3 3.2 3.7 8.4 2.7 4.2 4.7 1.9 2.7 1.5 8.7 8.6 7.9 10.1 0.4 16.4 17.3 2.0 8.4 8.2 6.3 0.0 9.7 9.3 1.5 0.8 5.0 12.4 8.2 8.2 1.6 9.8 1.8 7.2 0.8 7.2 10.3 0.4 2.6 5.2 26.7 10.0 5.8 4.5 23.3 3.1 4.0 3.8 31.7 7.1 7.4 59.2 27.6 34.9 7.2 6.4 10.1 6.8 1.6 4.5 5.4 5.1 4.6 DMWD "D19S593E, DMR-N9, gene59" ENSG00000185800 "DM1 locus, WD repeat containing" Q09019 19 45782947-45792845 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 60.5;Late spermatids: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068172, HPA069843" Approved Approved "Plasma membrane,Actin filaments" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Actin filaments" "HPA068172: AB_2685964, HPA069843: AB_2686212" "unprognostic (6.49e-2)" "unprognostic (3.35e-1)" "unprognostic (1.03e-2)" "unprognostic (1.65e-3)" "unprognostic (3.10e-2)" "unprognostic (2.39e-1)" "prognostic unfavorable (1.47e-4)" "unprognostic (5.11e-3)" "unprognostic (7.61e-2)" "unprognostic (7.26e-3)" "unprognostic (1.31e-2)" "unprognostic (2.16e-1)" "unprognostic (1.81e-1)" "unprognostic (1.85e-1)" "unprognostic (1.97e-1)" "unprognostic (1.18e-2)" "unprognostic (4.59e-2)" 24.6 19.1 27.7 12.3 23.4 7.3 23.0 10.5 31.7 29.1 10.8 40.3 9.7 39.6 6.7 18.2 29.4 11.8 43.1 30.0 18.6 18.7 10.2 22.6 11.2 17.5 19.9 29.1 18.1 10.3 29.6 15.0 15.1 25.2 7.4 11.9 17.1 12.2 44.0 15.5 18.3 14.8 8.9 17.0 25.0 36.5 20.2 10.3 23.1 20.1 7.1 30.6 23.2 14.5 31.6 34.3 30.4 21.2 18.1 22.9 23.3 26.9 18.8 23.5 21.2 20.6 17.1 13.2 15.4 30.4 28.8 23.4 16.1 13.4 12.3 38.6 30.0 11.4 37.3 18.2 22.4 1.4 17.6 21.5 16.2 22.0 31.2 26.7 20.3 8.3 28.2 28.9 18.6 25.8 16.0 9.0 13.8 20.6 22.2 16.3 11.0 14.5 14.6 29.7 30.4 33.6 28.9 22.2 19.5 13.4 19.4 7.7 43.3 27.0 26.6 18.1 40.7 41.1 27.4 15.0 28.1 2.1 31.8 0.6 0.2 0.2 1.4 0.6 1.1 0.6 1.2 1.1 0.2 1.4 0.4 0.8 0.6 1.8 0.8 0.2 0.7 0.3 27.7 23.4 10.5 31.7 30.0 18.6 17.5 19.9 15.1 8.9 20.2 14.5 18.8 6.4 4.7 8.1 6.9 8.4 13.9 4.5 2.2 34.5 11.8 9.8 28.5 10.0 4.4 9.2 60.5 7.3 10.6 10.4 5.9 7.3 17.2 12.4 18.9 16.2 26.3 9.3 8.1 10.6 9.6 15.3 6.1 11.2 11.4 23.3 20.0 4.6 2.0 52.2 7.5 7.9 10.2 4.8 11.4 57.7 17.1 2.6 5.4 5.6 0.9 23.3 14.4 10.1 5.8 13.8 7.2 17.0 6.8 11.5 5.6 7.1 8.9 41.2 13.1 24.5 19.0 10.8 15.7 4.6 7.0 5.5 9.0 20.6 8.1 11.5 DNAJC18 MGC29463 ENSG00000170464 "DnaJ heat shock protein family (Hsp40) member C18" Q9H819 5 139408588-139444491 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "testis: 77.9" "Group enriched" "Detected in many" 21 "Early spermatids: 529.9;Late spermatids: 1332.4" "Cancer enhanced" "Detected in many" "glioma: 8.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036538, HPA060154" Approved Approved "Cell Junctions,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 25: Spermatids - Spermatogenesis" "Cell Junctions" Cytosol "HPA036538: AB_10670802, HPA060154: AB_2684212" "unprognostic (2.03e-1)" "unprognostic (1.16e-1)" "unprognostic (1.13e-1)" "unprognostic (1.19e-3)" "unprognostic (1.15e-1)" "unprognostic (1.24e-1)" "unprognostic (2.73e-3)" "unprognostic (8.76e-2)" "unprognostic (1.03e-1)" "unprognostic (1.90e-1)" "prognostic favorable (5.89e-4)" "unprognostic (8.09e-2)" "unprognostic (1.69e-2)" "unprognostic (3.55e-2)" "unprognostic (1.81e-1)" "unprognostic (6.96e-2)" "unprognostic (1.97e-2)" 6.1 3.1 7.7 1.5 7.4 0.9 5.2 7.9 9.5 6.9 4.5 5.8 0.7 6.5 2.3 2.4 6.6 2.1 6.6 7.2 8.3 5.1 1.0 6.8 1.7 8.3 7.2 7.5 1.9 3.6 8.0 2.1 8.6 4.5 1.3 7.6 3.0 2.9 7.5 2.4 3.4 3.5 6.6 2.8 3.5 77.9 7.6 1.6 4.3 4.3 1.2 5.4 4.7 8.1 1.2 1.2 7.9 7.4 4.3 4.5 0.9 2.4 5.3 4.2 7.6 2.9 0.9 5.4 6.4 3.8 9.2 2.1 4.5 7.3 4.4 12.5 5.9 3.7 2.6 1.3 3.4 0.4 1.7 6.1 0.9 7.0 4.3 7.1 5.8 2.0 1.7 5.1 6.3 0.6 1.6 1.7 5.4 0.4 1.8 4.5 8.5 0.9 2.5 1.3 7.3 7.6 2.5 0.9 5.8 10.1 1.1 2.7 7.5 5.5 0.0 1.7 5.2 6.0 8.6 2.8 2.9 2.7 2.4 0.5 0.4 0.5 0.5 0.3 0.7 0.8 0.7 0.9 0.3 0.9 0.7 0.4 0.1 1.4 0.2 0.5 1.7 0.3 7.7 7.4 7.9 9.5 7.2 8.3 8.3 7.2 8.6 6.6 7.6 8.1 14.9 3.2 3.9 12.7 5.0 1.5 8.3 9.4 7.4 29.4 2.2 5.5 11.0 2.8 5.8 1.8 10.4 4.7 7.0 0.7 1.9 4.9 529.9 2.1 11.0 15.2 12.6 1.7 33.1 1.1 3.4 11.3 2.0 2.3 9.5 14.4 13.6 0.2 2.9 16.8 39.0 2.1 0.0 3.5 2.4 1332.4 14.0 3.4 5.4 8.4 3.7 13.7 3.1 17.6 22.1 2.0 1.7 18.8 7.6 3.9 0.8 3.6 3.3 20.1 19.7 21.1 14.2 43.8 12.9 2.6 1.1 4.7 4.2 9.8 1.3 3.4 DNAJC19 "Pam18, Tim14, TIMM14" ENSG00000205981 "DnaJ heat shock protein family (Hsp40) member C19" Q96DA6 3 180983709-180989774 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Translocation, Transport" Chaperone Cardiomyopathy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 471.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037782 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA037782: AB_10672611" "unprognostic (4.52e-2)" "unprognostic (3.55e-3)" "unprognostic (3.08e-2)" "unprognostic (2.45e-3)" "unprognostic (1.41e-1)" "unprognostic (5.54e-2)" "unprognostic (1.39e-1)" "unprognostic (1.14e-1)" "unprognostic (4.01e-2)" "prognostic favorable (8.53e-5)" "unprognostic (6.19e-2)" "unprognostic (1.76e-2)" "unprognostic (2.14e-2)" "unprognostic (1.75e-1)" "unprognostic (4.66e-1)" "unprognostic (3.33e-1)" "unprognostic (4.20e-3)" 22.7 44.1 26.1 11.1 27.1 10.8 26.4 27.2 39.7 19.4 28.8 27.5 21.4 18.9 33.0 22.9 21.3 11.8 73.4 27.2 28.0 50.2 48.9 14.7 16.3 26.4 29.3 26.5 27.9 34.7 30.9 14.2 26.3 22.6 17.7 27.2 28.1 18.2 65.8 15.0 18.1 11.8 27.6 18.5 26.2 11.6 26.8 20.7 25.6 77.8 13.4 23.5 18.4 28.1 53.9 14.0 38.8 29.6 45.6 27.0 35.4 30.2 18.2 29.1 25.5 49.0 26.2 23.0 63.9 25.5 70.9 26.8 37.8 36.5 35.9 36.5 49.1 27.0 24.5 48.3 48.9 64.9 27.5 25.9 29.8 24.4 43.0 37.9 34.0 55.2 42.8 35.8 23.0 44.2 48.5 54.6 51.2 75.9 44.8 31.4 26.9 69.6 43.3 24.8 38.7 20.6 30.8 75.8 82.3 44.0 85.2 45.2 16.8 18.5 27.1 26.3 54.4 47.7 60.7 80.1 19.0 49.9 22.9 33.6 20.4 31.5 33.3 22.3 39.8 34.7 38.5 34.7 28.6 29.8 39.8 40.6 4.4 26.8 27.3 36.4 35.0 30.8 26.1 27.1 27.2 39.7 27.2 28.0 26.4 29.3 26.3 27.6 26.8 28.1 68.3 38.5 52.5 11.1 66.3 56.6 68.6 105.4 56.9 31.7 138.6 183.0 151.7 120.1 70.1 77.3 14.6 116.6 67.4 57.9 471.6 83.9 9.1 57.4 50.4 61.4 45.2 48.8 18.7 109.3 111.2 71.7 30.1 42.7 110.7 79.7 68.6 167.0 68.0 48.8 20.5 90.7 91.6 35.5 59.8 13.2 85.1 42.8 74.7 9.4 58.6 91.4 74.2 13.0 21.4 79.9 66.1 72.6 47.7 91.5 101.0 216.8 58.7 67.6 85.5 80.3 108.8 82.1 56.3 73.9 60.1 68.7 68.4 121.4 86.7 69.2 DOC2B DOC2BL ENSG00000272636 "Double C2 domain beta" Q14184 17 142789-181650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.5;retina: 24.6" "Group enriched" "Detected in many" 5 "Adipocytes: 49.4;Cone photoreceptor cells: 175.2;Muller glia cells: 146.7;Rod photoreceptor cells: 100.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "SH-SY5Y: 37.2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 56.1" HPA043168 Uncertain NA NA "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "HPA043168: AB_2678349" "prognostic favorable (3.45e-4)" "unprognostic (2.28e-3)" "unprognostic (3.17e-1)" "unprognostic (1.72e-1)" "unprognostic (1.08e-1)" "prognostic favorable (8.68e-4)" "unprognostic (1.25e-1)" "unprognostic (3.61e-2)" "unprognostic (2.62e-1)" "unprognostic (8.78e-3)" "unprognostic (3.49e-2)" "unprognostic (2.18e-1)" "unprognostic (2.27e-3)" "unprognostic (2.06e-2)" "unprognostic (1.71e-1)" "unprognostic (1.27e-3)" "unprognostic (4.87e-3)" 15.9 4.5 11.6 3.0 12.7 6.2 13.9 18.6 21.1 3.7 1.3 4.0 0.0 4.0 0.0 14.4 5.8 0.0 5.3 22.5 6.5 8.7 0.7 3.4 1.3 8.7 11.7 1.1 10.0 0.2 6.7 1.4 10.8 3.6 1.1 24.6 2.1 0.6 2.7 4.4 4.5 1.5 12.6 3.3 3.4 0.3 12.2 0.8 3.0 0.1 2.5 4.4 5.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 12.7 18.6 21.1 22.5 6.5 8.7 11.7 10.8 12.6 12.2 0.9 49.4 0.0 2.3 0.3 0.2 0.0 0.8 0.0 2.2 10.1 1.5 1.3 2.0 0.0 0.0 9.2 175.2 0.0 0.0 0.2 0.0 0.2 1.1 0.7 4.6 22.8 0.0 0.0 3.8 4.2 0.0 2.3 9.2 0.8 0.0 0.1 18.5 0.2 0.1 1.7 2.3 0.0 0.0 0.3 0.0 2.5 0.0 0.5 0.0 1.0 0.6 146.7 0.0 1.5 0.1 4.3 0.0 0.0 0.0 0.9 0.0 0.5 1.5 100.7 0.0 2.3 0.8 0.2 0.1 1.8 0.0 0.3 0.1 0.8 0.2 3.6 DOK2 "Dok-2, p56dok-2" ENSG00000147443 "Docking protein 2" O60496 8 21908873-21913690 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 25.6;lymphoid tissue: 40.9" "Cell type enhanced" "Detected in many" "dendritic cells: 130.6;Hofbauer cells: 131.8;Kupffer cells: 171.8;Langerhans cells: 288.4;Macrophages: 181.5;NK-cells: 344.0;T-cells: 147.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1565.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 25.3;HEL: 54.3;HMC-1: 119.8;JURKAT: 22.3;THP-1: 43.1;U-937: 42.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB004379, HPA005507, HPA066571" Enhanced Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus,Cytosol" NA NA 220000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Nucleoplasm, Nuclear bodies, Golgi apparatus" "CAB004379: AB_627449, HPA005507: , HPA066571: AB_2732749" "unprognostic (5.39e-2)" "unprognostic (8.84e-3)" "unprognostic (8.72e-3)" "unprognostic (1.74e-3)" "unprognostic (2.14e-2)" "unprognostic (2.30e-3)" "unprognostic (1.34e-1)" "unprognostic (7.22e-2)" "prognostic favorable (4.31e-4)" "unprognostic (2.22e-1)" "unprognostic (4.19e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (1.88e-1)" "unprognostic (1.24e-2)" "unprognostic (3.19e-1)" "unprognostic (2.80e-1)" 9.5 5.0 1.1 26.5 1.2 19.5 5.0 1.2 2.3 1.9 2.5 5.5 7.0 2.2 0.5 2.3 3.5 6.5 3.5 1.3 1.3 3.0 6.1 25.6 26.3 1.4 1.5 1.4 1.9 0.5 1.1 7.9 1.5 2.3 3.6 0.0 3.4 1.5 2.0 2.3 9.5 6.9 1.2 40.9 6.8 1.6 4.5 16.4 2.4 1.6 7.8 8.4 2.3 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.3 0.0 54.3 0.0 0.1 0.0 0.4 119.8 0.0 0.0 0.0 0.0 0.0 0.0 22.3 0.8 5.0 0.0 0.0 0.9 8.7 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.3 0.0 0.1 0.2 0.1 0.2 0.1 0.3 1.4 42.0 0.2 577.6 484.3 1565.6 398.3 624.0 184.5 14.5 274.3 304.8 421.9 6.6 151.0 185.9 37.2 307.6 580.7 7.6 597.2 810.3 1.1 1.2 1.2 2.3 1.3 1.3 1.4 1.5 1.5 1.2 4.5 1.5 2.0 3.2 18.1 0.0 13.2 11.5 0.6 0.0 0.0 0.0 1.2 1.8 2.1 0.0 1.3 3.7 0.0 0.7 130.6 0.3 0.0 0.1 0.2 0.2 0.5 2.8 0.0 10.5 0.1 0.0 1.0 2.6 3.1 0.4 36.3 0.1 5.7 1.1 131.8 0.0 0.0 0.2 0.0 171.8 288.4 0.6 0.3 181.5 19.6 0.0 74.8 0.0 344.0 0.0 0.0 0.0 0.0 0.0 15.4 0.2 0.0 0.7 1.5 0.0 0.0 0.6 2.5 0.2 4.3 0.7 8.5 1.0 147.4 0.0 0.2 0.8 DPCD "DKFZP566F084, RP11-529I10.4" ENSG00000166171 "Deleted in primary ciliary dyskinesia homolog (mouse)" Q9BVM2 10 101570560-101609662 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 132.4" "Group enriched" "Detected in many" 4 "Early spermatids: 579.4;Late spermatids: 1068.7;Respiratory ciliated cells: 329.7;Spermatocytes: 313.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 20.2;intermediate monocyte: 22.2;myeloid DC: 29.6;non-classical monocyte: 9.5" "Group enriched" "Detected in all" 14 "dendritic cells: 29.6;monocytes: 22.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036603, HPA036604" Enhanced Approved "Nuclear speckles" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear speckles" "HPA036603: AB_2675212, HPA036604: AB_10673503" "unprognostic (1.22e-2)" "unprognostic (1.73e-3)" "unprognostic (4.66e-1)" "prognostic favorable (6.57e-4)" "unprognostic (1.90e-1)" "unprognostic (9.13e-2)" "unprognostic (4.00e-3)" "unprognostic (1.71e-1)" "unprognostic (1.67e-1)" "unprognostic (1.09e-1)" "unprognostic (1.08e-1)" "unprognostic (1.64e-1)" "unprognostic (4.55e-2)" "unprognostic (2.70e-1)" "unprognostic (5.04e-2)" "unprognostic (3.83e-2)" "unprognostic (7.54e-2)" 10.5 18.7 35.1 8.7 37.2 11.8 19.4 31.5 42.0 21.8 55.1 17.3 6.8 16.7 41.3 20.4 73.3 15.5 29.6 37.4 39.1 30.9 10.4 14.0 6.2 36.2 37.1 23.5 14.7 49.3 49.5 10.6 36.5 16.1 13.5 55.8 21.2 15.7 19.2 13.2 7.1 18.0 33.3 4.5 14.4 132.4 39.7 6.6 33.0 18.3 8.2 14.4 14.9 33.4 97.1 53.4 37.9 77.2 35.2 61.7 15.6 44.5 53.6 59.4 55.1 38.8 51.4 9.0 74.6 42.7 25.2 54.0 55.4 65.3 61.2 23.0 57.5 11.3 49.8 56.7 20.3 58.8 8.1 42.3 54.8 72.0 56.1 153.7 50.8 14.0 32.4 12.6 45.1 122.9 0.0 48.1 28.7 26.9 41.6 0.0 51.8 20.5 92.6 25.3 37.1 63.3 36.5 23.4 31.3 34.1 71.2 23.9 35.5 27.3 24.9 55.7 62.3 37.9 45.9 16.9 94.7 13.7 11.7 0.0 20.2 1.0 1.8 22.2 1.7 1.3 1.4 1.4 29.6 0.7 1.5 1.8 0.9 1.6 9.5 4.1 0.6 8.1 35.1 37.2 31.5 42.0 37.4 39.1 36.2 37.1 36.5 33.3 39.7 33.4 6.9 35.3 12.4 4.9 2.1 9.7 29.5 89.2 9.6 16.4 25.4 29.5 33.7 30.0 56.6 49.7 18.8 24.6 0.9 10.5 95.9 63.3 579.4 136.5 23.5 11.1 23.9 14.1 7.7 27.5 16.7 21.2 10.2 20.2 1.3 19.2 11.4 10.9 24.0 11.8 6.2 12.5 52.9 4.4 14.6 1068.7 23.6 8.7 16.0 3.7 6.9 27.8 2.1 4.0 1.4 33.9 12.4 27.8 5.6 18.6 3.5 117.3 329.7 49.1 0.0 12.4 29.0 313.8 77.4 8.7 14.2 10.7 2.9 25.3 22.1 23.9 DPYD DPD ENSG00000188641 "Dihydropyrimidine dehydrogenase" Q12882 1 97077743-97995000 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 68.5" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 1712.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033241, HPA045210" Uncertain NA NA 1600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "CAB033241: AB_2094323, HPA045210: AB_2679256" "unprognostic (2.33e-2)" "unprognostic (1.69e-1)" "unprognostic (9.82e-3)" "unprognostic (1.04e-1)" "unprognostic (1.13e-2)" "unprognostic (8.81e-2)" "unprognostic (2.86e-1)" "unprognostic (3.05e-1)" "unprognostic (1.56e-1)" "unprognostic (9.29e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (6.54e-2)" "unprognostic (5.32e-2)" "unprognostic (1.43e-1)" "unprognostic (3.43e-2)" "unprognostic (3.71e-1)" "unprognostic (2.25e-1)" 22.2 13.2 7.2 22.6 12.8 10.3 16.7 5.7 10.4 18.8 2.4 11.9 21.9 14.9 8.4 17.1 14.3 25.7 8.9 7.4 12.9 12.6 68.5 29.6 16.6 12.4 9.4 24.0 11.8 9.2 6.2 4.5 12.1 9.9 10.1 3.3 15.0 13.4 5.8 7.1 19.4 18.2 6.9 24.7 8.4 3.7 12.9 17.0 10.3 10.1 12.0 18.2 14.2 24.4 22.2 6.2 7.8 0.2 42.4 72.5 0.1 35.2 31.9 32.1 23.6 0.0 9.2 11.7 50.6 32.9 5.1 5.2 0.0 8.3 58.7 11.6 7.3 10.0 11.1 0.2 18.8 4.5 0.6 57.5 3.0 25.7 29.3 67.7 26.8 6.8 0.4 36.4 17.0 0.0 23.6 6.4 0.9 0.2 7.5 0.1 37.1 18.6 39.4 0.1 11.1 8.8 30.1 2.5 0.3 0.8 0.0 10.2 30.9 69.2 5.0 56.4 70.6 3.0 0.1 0.2 10.2 12.6 56.2 18.2 61.1 4.1 11.6 29.5 14.8 2.2 13.3 11.0 32.7 4.9 12.5 11.1 59.8 13.3 27.1 0.9 15.8 21.9 7.2 12.8 5.7 10.4 7.4 12.9 12.4 9.4 12.1 6.9 12.9 24.4 25.5 16.0 39.1 23.8 15.4 7.6 8.8 9.4 18.8 2.5 8.4 8.3 5.3 40.0 11.5 7.3 0.0 0.2 19.2 3.3 5.9 2.5 7.0 1.5 15.2 14.7 3.0 13.3 258.6 6.4 0.2 30.0 10.7 1.7 9.5 4.5 17.2 54.2 17.1 0.0 30.5 5.5 6.1 130.4 27.0 4.0 33.5 73.7 3.6 105.9 98.1 4.8 27.8 34.2 1712.3 5.3 2.1 18.8 17.0 4.9 21.0 6.6 8.6 0.1 13.1 16.0 17.7 1.2 3.1 19.7 5.5 0.1 31.4 5.1 6.8 9.3 EBAG9 "EB9, RCAS1" ENSG00000147654 "Estrogen receptor binding site associated antigen 9" O00559 8 109539711-109565996 "Cancer-related genes, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021153, HPA021154, CAB072810, CAB072811, CAB072812" Enhanced Enhanced "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus" "CAB072810: , CAB072811: , CAB072812: , HPA021153: AB_1856151, HPA021154: AB_1856152" "unprognostic (3.04e-2)" "unprognostic (9.99e-2)" "unprognostic (2.08e-1)" "unprognostic (1.99e-1)" "unprognostic (5.06e-2)" "unprognostic (8.13e-2)" "unprognostic (2.63e-1)" "unprognostic (3.17e-2)" "unprognostic (1.72e-1)" "unprognostic (4.22e-2)" "unprognostic (1.04e-1)" "unprognostic (3.72e-1)" "unprognostic (9.72e-3)" "unprognostic (6.46e-2)" "unprognostic (5.16e-1)" "unprognostic (3.53e-1)" "unprognostic (3.71e-2)" 23.3 28.4 18.6 17.6 19.9 16.9 32.4 23.4 26.3 36.1 19.8 28.6 23.5 22.8 44.7 17.0 27.6 19.4 24.7 19.1 20.5 37.0 45.2 28.1 25.4 18.9 19.0 22.2 36.7 34.9 20.5 18.1 19.0 23.3 31.2 32.5 42.9 27.6 53.2 17.9 21.0 17.0 19.1 20.7 27.2 25.3 19.3 20.6 57.4 42.3 27.0 17.2 15.3 20.2 36.7 25.2 25.3 17.3 15.3 24.9 19.7 19.5 14.6 27.0 25.4 25.7 38.1 51.7 33.0 13.8 21.8 25.2 24.4 31.3 28.5 57.6 26.9 56.9 15.8 39.6 34.3 20.0 16.1 19.9 60.1 23.4 47.2 21.9 25.7 45.8 59.8 37.0 24.0 55.8 58.2 31.5 15.8 70.1 25.2 30.9 20.1 43.7 31.4 23.7 27.6 22.1 21.3 22.6 27.6 18.4 44.7 25.6 17.5 20.9 15.0 19.1 14.4 54.9 38.3 48.7 21.2 52.7 19.6 5.8 13.4 14.7 19.3 19.5 34.1 40.7 27.1 27.0 22.5 40.3 33.5 30.4 2.8 29.4 17.3 23.8 33.4 14.7 18.6 19.9 23.4 26.3 19.1 20.5 18.9 19.0 19.0 19.1 19.3 20.2 32.0 121.8 102.4 12.7 40.2 21.7 28.6 51.8 44.9 34.5 36.8 46.0 37.6 54.3 65.1 29.5 6.2 50.2 24.0 33.6 64.6 47.3 134.7 42.9 26.7 34.5 31.8 36.0 16.1 65.8 34.0 28.8 22.4 33.0 46.9 16.0 23.2 48.8 32.7 50.5 16.1 39.4 50.8 24.7 22.1 115.0 29.2 27.9 19.6 11.2 25.3 53.4 27.8 18.1 16.1 38.5 41.3 23.0 53.8 36.8 50.5 58.5 61.8 34.7 32.9 35.1 32.1 101.6 50.4 40.5 19.9 22.2 28.5 34.7 46.0 31.7 EBI3 "IL27B, IL35B" ENSG00000105246 "Epstein-Barr virus induced 3" Q14213 19 4229523-4237528 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "placenta: 147.6" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 485.6;monocytes: 505.7;Syncytiotrophoblasts: 336.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "intermediate monocyte: 4.8;memory B-cell: 18.7;naive B-cell: 14.7;non-classical monocyte: 6.3" "Group enriched" "Detected in many" 14 "B-cells: 18.7;monocytes: 6.3" "Cell line enriched" "Detected in some" 13 "HDLM-2: 218.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA046635 Enhanced "Secreted to blood" NA NA 203000 1400000 "Cluster 19: B-cells - Humoral immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 44: HDLM-2 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA046635: AB_2679729" "unprognostic (7.26e-2)" "unprognostic (1.49e-2)" "unprognostic (9.44e-2)" "unprognostic (1.31e-1)" "unprognostic (2.59e-1)" "unprognostic (2.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.10e-2)" "unprognostic (7.78e-2)" "unprognostic (4.87e-2)" "unprognostic (4.25e-3)" "unprognostic (8.27e-2)" "prognostic unfavorable (1.04e-8)" "unprognostic (1.97e-1)" "unprognostic (2.78e-2)" "unprognostic (9.29e-2)" "unprognostic (4.67e-2)" 4.7 4.7 3.8 14.6 3.3 1.2 1.7 3.4 5.3 1.5 3.2 3.0 4.3 1.1 0.1 1.0 2.4 5.4 1.4 3.8 3.7 2.1 3.3 2.9 20.2 5.7 4.2 1.3 2.5 0.4 1.7 147.6 5.2 1.8 1.6 0.1 1.8 1.4 0.2 0.6 8.4 2.1 4.5 34.0 3.7 0.9 5.8 9.4 0.9 0.4 7.3 4.8 1.0 6.1 0.1 1.7 0.1 0.0 0.0 0.0 7.3 0.7 4.2 0.4 0.2 1.3 1.2 4.2 16.4 0.0 2.0 0.1 0.0 0.0 0.0 218.8 0.0 0.0 0.1 0.2 0.3 0.0 7.7 0.4 0.0 2.1 0.6 1.6 0.1 0.0 0.4 0.5 0.1 0.1 0.0 3.0 0.4 0.0 0.0 0.0 0.6 0.3 2.6 0.0 0.2 0.4 0.0 0.0 0.0 2.7 0.2 0.2 0.9 0.3 5.1 0.0 0.2 0.4 0.0 0.2 0.3 0.0 0.6 0.0 0.1 0.0 0.0 4.8 0.0 18.7 0.0 0.0 0.8 14.7 0.0 0.0 0.2 0.0 6.3 0.0 0.0 0.6 3.8 3.3 3.4 5.3 3.8 3.7 5.7 4.2 5.2 4.5 5.8 6.1 0.5 0.0 0.5 0.3 8.4 0.4 0.0 13.3 0.0 0.0 0.2 0.6 0.1 1.5 10.7 0.0 0.0 10.6 0.5 0.0 0.0 2.8 0.0 0.3 0.4 1.3 0.0 0.0 0.6 0.9 485.6 0.7 0.0 0.3 11.4 0.0 1.1 0.1 9.6 0.0 0.4 0.0 6.1 102.6 11.3 0.0 0.0 19.0 0.0 5.6 505.7 0.1 0.0 0.0 0.1 0.6 0.0 0.0 2.6 0.1 0.0 0.6 1.5 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.1 336.4 1.0 0.1 0.0 0.1 EBPL EBRP ENSG00000123179 "EBP like" Q9BY08 13 49660674-49691486 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 99.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 305.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049891 Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 30: Non-specific - Translation" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum" "HPA049891: AB_2680937" "unprognostic (1.49e-1)" "unprognostic (1.41e-2)" "unprognostic (4.23e-2)" "unprognostic (3.06e-2)" "unprognostic (2.81e-1)" "unprognostic (8.63e-3)" "unprognostic (3.91e-2)" "unprognostic (1.57e-1)" "unprognostic (6.91e-2)" "prognostic unfavorable (1.38e-4)" "unprognostic (1.63e-2)" "unprognostic (2.67e-2)" "prognostic unfavorable (7.18e-8)" "unprognostic (1.11e-2)" "unprognostic (1.11e-1)" "unprognostic (3.03e-1)" "unprognostic (1.95e-2)" 21.9 59.7 6.6 12.1 6.5 20.0 23.2 7.0 8.9 37.0 7.5 24.1 14.2 20.4 6.6 62.3 25.5 11.1 8.7 6.7 7.3 14.8 99.3 19.1 11.0 6.8 6.8 33.3 47.7 10.5 10.3 11.2 6.9 21.3 16.3 4.4 27.9 13.5 5.2 33.7 14.3 13.3 7.8 14.4 27.5 11.0 7.9 10.3 16.1 2.5 11.0 23.8 47.6 8.4 46.7 34.9 21.0 88.5 26.0 66.4 37.5 48.5 33.1 30.9 25.0 66.8 65.1 57.9 21.6 23.7 27.1 93.7 38.3 47.4 45.0 46.4 126.8 43.7 23.4 83.3 75.2 69.4 35.0 77.7 100.4 25.6 68.1 49.9 53.6 61.5 36.7 23.0 40.2 25.0 27.4 124.8 72.4 153.2 78.2 58.5 11.7 89.0 66.4 15.2 19.5 50.1 18.0 62.1 21.6 21.7 54.4 54.0 24.6 23.4 23.2 20.2 40.7 14.9 41.2 46.7 11.2 68.6 21.6 2.4 3.0 0.8 2.4 3.6 6.8 4.3 4.8 5.0 5.0 5.4 7.1 4.1 6.4 4.1 3.9 3.3 3.7 1.4 6.6 6.5 7.0 8.9 6.7 7.3 6.8 6.8 6.9 7.8 7.9 8.4 75.5 35.3 23.1 9.8 46.5 108.6 157.6 17.4 115.5 7.9 139.8 192.1 5.4 104.4 17.4 23.9 8.4 32.3 25.5 26.5 41.1 61.2 13.3 61.5 90.6 76.8 27.8 65.6 8.0 52.1 37.1 56.9 56.6 50.0 17.8 64.9 78.9 305.3 38.5 1.7 11.6 80.1 8.2 45.8 36.5 10.0 94.1 27.4 46.2 8.4 30.9 23.6 36.0 8.0 5.1 41.0 42.0 70.0 79.3 116.6 16.5 62.3 8.5 8.4 19.7 57.7 52.7 26.9 17.2 208.6 154.6 15.2 40.3 194.2 133.6 108.9 ECHDC1 dJ351K20.2 ENSG00000093144 "Ethylmalonyl-CoA decarboxylase 1" Q9NTX5 6 127288712-127343609 "Enzymes, Plasma proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 230.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035445, HPA035446" Uncertain Approved Vesicles NA NA 56000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA035445: AB_10669860, HPA035446: AB_2732468" "unprognostic (9.57e-2)" "unprognostic (1.63e-2)" "unprognostic (2.46e-3)" "unprognostic (1.34e-1)" "unprognostic (4.09e-1)" "unprognostic (3.68e-2)" "unprognostic (5.03e-3)" "unprognostic (4.89e-3)" "unprognostic (4.97e-2)" "unprognostic (1.76e-1)" "unprognostic (3.99e-1)" "unprognostic (9.97e-2)" "unprognostic (8.21e-3)" "unprognostic (6.83e-2)" "unprognostic (2.86e-1)" "unprognostic (1.39e-1)" "unprognostic (1.40e-2)" 92.9 29.4 21.8 36.8 24.5 16.2 37.3 26.4 28.6 36.4 32.3 58.4 46.8 21.4 23.0 33.5 23.2 27.5 42.6 22.0 27.0 92.5 93.8 56.8 41.3 28.1 24.7 21.1 27.9 26.2 14.1 36.2 28.5 33.8 53.8 30.0 46.3 28.4 39.3 22.7 40.7 33.4 24.4 28.4 37.0 18.2 24.7 41.1 38.7 52.2 42.6 43.4 23.4 32.3 58.3 45.6 64.0 59.3 92.9 87.7 54.1 92.7 112.1 78.0 99.0 79.7 43.1 87.6 77.8 88.6 88.4 46.9 0.1 69.6 98.3 52.4 43.3 116.9 58.4 128.3 82.6 158.0 63.4 99.6 81.9 73.1 61.6 70.6 71.8 63.2 147.6 51.6 105.7 55.1 105.7 73.5 52.9 29.0 55.8 49.0 78.7 72.3 142.8 70.8 73.3 71.2 52.1 1.8 131.3 48.3 1.8 182.6 75.2 47.8 76.9 121.8 104.8 65.7 141.0 116.3 87.2 136.4 114.7 19.0 71.6 24.0 23.4 57.5 24.7 28.6 19.8 22.9 66.6 29.2 23.7 24.2 28.6 15.3 43.1 50.5 22.1 43.9 21.8 24.5 26.4 28.6 22.0 27.0 28.1 24.7 28.5 24.4 24.7 32.3 37.0 96.1 114.0 32.3 59.7 26.1 42.3 94.2 35.3 26.4 30.8 28.3 60.8 32.9 102.4 31.3 31.3 106.8 49.3 35.6 127.2 76.1 64.7 47.0 48.3 32.6 13.8 22.9 47.4 79.5 85.6 45.8 38.2 40.2 43.7 32.9 26.0 68.8 85.8 28.6 41.0 35.7 59.0 48.4 38.7 24.4 32.9 55.9 35.6 40.3 55.3 33.5 47.4 55.3 95.0 54.4 41.1 31.2 48.3 31.1 74.4 230.3 47.0 42.3 26.3 55.7 33.0 27.6 28.6 34.7 22.9 65.5 46.3 88.2 56.9 52.7 ECRG4 "augurin, C2orf40" ENSG00000119147 "ECRG4 augurin precursor" Q9H1Z8 2 106063246-106078155 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 225.3" "Cell type enhanced" "Detected in some" "Adipocytes: 87.6;Fibroblasts: 25.3;Smooth muscle cells: 19.1" "Cancer enriched" "Detected in many" 11 "thyroid cancer: 72.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 8.5;naive CD8 T-cell: 7.2" "Lineage enriched" "Detected in single" 83 "T-cells: 8.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008546 Uncertain "Secreted to blood" NA NA 330000 "Cluster 32: T-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: Fibroblasts - ECM organization" "HPA008546: AB_2066524" "prognostic favorable (4.58e-4)" "unprognostic (3.91e-1)" "unprognostic (2.44e-2)" "unprognostic (1.34e-2)" "unprognostic (1.09e-1)" "unprognostic (2.32e-1)" "unprognostic (1.61e-3)" "unprognostic (6.56e-3)" "unprognostic (1.82e-2)" "unprognostic (1.25e-1)" "unprognostic (2.35e-3)" "unprognostic (1.36e-2)" "unprognostic (1.06e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (9.11e-3)" "unprognostic (1.30e-4)" 66.7 27.6 5.3 1.1 6.0 0.0 49.6 9.6 5.3 73.8 225.3 47.6 5.3 24.6 28.4 20.2 47.5 9.4 25.7 12.0 13.0 47.1 3.2 27.6 1.7 14.9 21.5 13.2 5.9 0.7 96.2 8.5 15.4 55.1 5.6 0.1 20.4 101.8 10.3 14.1 19.2 9.0 19.4 25.8 165.8 27.0 12.2 2.8 101.1 6.9 0.3 79.6 58.2 11.7 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.1 2.0 1.3 0.0 0.0 8.5 7.2 0.0 0.0 0.0 0.0 0.8 1.4 5.3 6.0 9.6 5.3 12.0 13.0 14.9 21.5 15.4 19.4 12.2 11.7 87.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.0 25.3 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.1 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 EDNRB "ETB, HSCR, HSCR2" ENSG00000136160 "Endothelin receptor type B" P24530 13 77895481-77975529 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Albinism, Deafness, Disease variant, FDA approved drug targets, Hirschsprung disease, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 127.8" "Cell type enhanced" "Detected in many" "Adipocytes: 120.5;Astrocytes: 126.3;Hepatic stellate cells: 112.5;Melanocytes: 110.3;Muller glia cells: 116.2;Sertoli cells: 216.9;Skeletal myocytes: 81.3;Smooth muscle cells: 102.1" "Cancer enhanced" "Detected in all" "melanoma: 127.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 68.0;ASC diff: 50.5;SK-MEL-30: 66.0;U-266/70: 40.7;WM-115: 131.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017842, HPA027546" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Cytosol "CAB017842: , HPA027546: AB_2672327" "unprognostic (7.75e-2)" "unprognostic (6.73e-2)" "unprognostic (1.41e-3)" "unprognostic (2.59e-2)" "unprognostic (8.37e-2)" "unprognostic (2.45e-3)" "unprognostic (4.17e-3)" "unprognostic (5.43e-2)" "unprognostic (1.02e-1)" "unprognostic (1.38e-2)" "unprognostic (3.40e-2)" "unprognostic (3.01e-2)" "prognostic favorable (7.20e-5)" "unprognostic (1.59e-2)" "unprognostic (3.86e-2)" "unprognostic (4.58e-2)" "unprognostic (6.77e-3)" 58.8 41.2 34.7 19.5 50.8 0.9 39.8 44.6 26.1 18.7 6.7 13.0 20.0 13.1 3.7 8.2 14.1 14.9 28.1 27.5 51.6 33.0 50.9 51.2 10.4 76.2 66.0 4.7 11.4 15.3 9.6 127.8 47.9 25.3 13.2 17.9 27.0 6.9 11.3 12.5 21.9 12.9 97.2 16.8 10.6 2.3 64.9 4.0 31.8 18.8 4.7 23.6 15.5 78.7 5.7 0.0 68.0 0.0 50.5 2.0 1.0 0.0 0.1 0.0 0.0 25.9 0.0 0.0 2.6 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.3 0.3 0.0 0.0 3.5 0.0 0.2 13.2 0.0 0.0 0.0 0.1 0.6 0.0 0.2 0.2 1.7 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.1 0.5 0.1 0.0 66.0 8.9 0.0 0.3 0.3 0.6 0.1 0.0 0.4 40.7 24.9 0.1 1.2 0.0 131.8 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 34.7 50.8 44.6 26.1 27.5 51.6 76.2 66.0 47.9 97.2 64.9 78.7 120.5 12.8 51.0 126.3 0.2 14.8 1.0 0.0 1.2 5.8 1.2 2.8 10.8 0.0 2.5 0.0 6.2 14.7 0.3 0.1 0.0 0.0 2.9 2.9 20.7 73.3 0.0 0.0 1.3 0.0 13.9 51.1 1.1 35.9 6.3 2.1 112.5 1.1 13.4 0.0 1.6 0.0 0.0 18.7 10.6 2.2 79.9 5.2 110.3 6.5 0.1 116.2 0.0 48.2 0.9 0.1 0.0 2.6 0.1 2.6 0.0 0.1 1.5 4.4 216.9 81.3 102.1 0.4 2.1 0.2 7.2 5.7 1.6 2.5 0.0 1.5 EGLN3 "HIFPH3, PHD3" ENSG00000129521 "Egl-9 family hypoxia inducible factor 3" Q9H6Z9 14 33924227-34462774 "Enzymes, Predicted intracellular proteins" "Apoptosis, DNA damage" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 110.3;skin 1: 118.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 213.7;Cardiomyocytes: 105.8;Distal enterocytes: 135.5;Extravillous trophoblasts: 115.9;Suprabasal keratinocytes: 231.6" "Cancer enhanced" "Detected in all" "renal cancer: 50.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 25.5" "Lineage enriched" "Detected in many" 14 "dendritic cells: 25.5" "Cell line enhanced" "Detected in many" "RH-30: 44.6;RPTEC TERT1: 38.2;RT4: 122.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064895 Supported Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA064895: AB_2685384" "unprognostic (3.58e-2)" "unprognostic (4.76e-3)" "unprognostic (1.75e-1)" "unprognostic (8.87e-2)" "unprognostic (6.88e-2)" "unprognostic (1.38e-2)" "prognostic unfavorable (2.14e-5)" "unprognostic (1.39e-3)" "unprognostic (3.44e-2)" "unprognostic (1.79e-1)" "unprognostic (2.93e-2)" "unprognostic (2.90e-1)" "prognostic unfavorable (2.50e-4)" "unprognostic (1.37e-1)" "unprognostic (5.21e-2)" "unprognostic (4.71e-2)" "unprognostic (6.30e-2)" 14.6 0.8 32.9 9.4 40.9 0.3 10.0 38.2 37.5 12.3 15.4 25.9 35.7 10.0 4.4 27.0 9.4 13.8 110.3 29.7 38.9 16.3 4.9 8.3 5.7 34.3 37.5 2.1 4.3 0.3 3.4 25.4 32.2 9.1 20.0 15.2 11.2 12.0 20.8 118.2 40.9 11.7 31.9 4.9 37.7 1.1 42.9 4.9 2.8 6.4 9.8 51.3 20.8 36.1 31.1 8.0 0.9 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 8.2 0.0 10.0 0.1 0.9 0.9 15.0 29.4 0.0 3.1 8.0 8.3 20.5 1.0 0.0 0.0 0.4 4.0 14.5 0.0 0.1 0.0 0.0 2.3 16.9 0.0 0.4 2.7 0.7 0.1 24.3 26.7 2.8 0.0 44.6 11.1 38.2 122.9 6.2 7.0 2.0 11.8 3.2 18.2 12.0 0.1 0.0 0.2 3.2 0.0 1.8 0.4 6.7 0.1 7.2 0.0 0.5 0.0 0.0 1.8 0.1 0.0 0.0 0.0 1.2 0.9 2.6 0.0 0.1 0.1 0.1 1.1 0.0 25.5 0.0 0.9 32.9 40.9 38.2 37.5 29.7 38.9 34.3 37.5 32.2 31.9 42.9 36.1 6.0 0.0 0.6 36.2 1.6 213.7 49.0 56.6 3.4 11.6 16.0 17.0 105.8 4.3 24.8 9.2 2.1 11.4 16.0 135.5 9.8 15.6 1.8 42.3 8.5 25.1 16.2 0.4 1.0 6.9 115.9 16.8 74.9 17.2 1.3 0.1 12.5 0.3 3.1 1.7 4.3 31.6 12.2 1.9 62.8 4.9 2.5 10.8 40.9 0.0 0.9 11.6 0.0 6.6 54.2 46.6 41.9 0.7 0.4 17.4 59.7 20.5 37.2 2.4 0.0 17.7 9.4 1.7 0.3 4.1 231.6 103.0 4.5 1.2 14.1 25.7 EHF "ESE3, ESEJ" ENSG00000135373 "ETS homologous factor" Q9NZC4 11 34621093-34663288 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 287.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 400.8;Basal respiratory cells: 271.6;Club cells: 323.3;Endometrial ciliated cells: 229.6;Glandular and luminal cells: 281.8;Squamous epithelial cells: 251.1;Urothelial cells: 397.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 11 "myeloid DC: 1.7" "Lineage enriched" "Detected in single" 11 "dendritic cells: 1.7" "Cell line enhanced" "Detected in some" "CAPAN-2: 138.4;HaCaT: 95.7;HBEC3-KT: 107.6;OE19: 132.9;RT4: 214.8;T-47d: 213.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA050923, HPA060734" Enhanced Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" No NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Golgi apparatus" "HPA050923: AB_2681275, HPA060734: AB_2684351" "unprognostic (1.06e-2)" "unprognostic (1.06e-1)" "prognostic favorable (5.81e-4)" "unprognostic (2.82e-1)" "unprognostic (5.62e-2)" "unprognostic (1.22e-3)" "unprognostic (2.44e-1)" "unprognostic (2.04e-1)" "unprognostic (1.38e-1)" "unprognostic (6.79e-2)" "prognostic unfavorable (6.94e-4)" "unprognostic (1.29e-1)" "unprognostic (6.26e-2)" "unprognostic (3.47e-3)" "unprognostic (2.24e-1)" "unprognostic (2.89e-1)" "unprognostic (7.08e-2)" 0.9 1.1 0.9 14.7 1.7 0.2 199.5 0.9 0.6 120.8 1.3 99.3 42.2 13.9 95.0 200.7 129.6 32.2 0.3 1.1 0.8 25.7 1.3 23.4 1.5 2.6 4.0 0.2 41.1 18.5 0.7 0.1 2.8 82.7 126.3 0.8 287.7 153.4 0.2 53.6 34.1 3.5 2.5 1.2 59.5 0.7 1.3 1.3 2.5 0.0 67.3 50.7 79.2 4.7 46.5 26.8 0.0 0.3 0.0 0.0 0.8 0.0 3.9 0.0 0.2 0.4 138.4 0.1 17.1 0.0 0.2 95.7 0.0 107.6 0.5 0.1 0.2 0.0 1.5 0.2 0.0 0.2 0.0 0.0 41.7 0.3 0.2 0.0 0.0 0.0 0.3 0.0 0.1 2.6 0.1 0.8 0.2 132.9 1.0 0.0 0.1 1.0 20.2 214.8 0.0 0.2 0.5 14.8 0.2 0.0 213.5 0.5 0.0 0.2 1.2 5.1 0.4 0.5 0.2 0.3 0.3 0.2 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.7 0.9 0.6 1.1 0.8 2.6 4.0 2.8 2.5 1.3 4.7 0.8 48.1 97.2 1.3 0.6 109.6 400.8 271.6 133.1 0.0 123.0 51.9 0.9 60.1 323.3 55.2 0.0 0.1 1.1 62.7 15.6 77.8 14.2 229.6 17.7 4.0 23.3 0.0 0.7 86.5 0.0 3.2 53.5 281.8 1.3 0.0 0.0 0.4 0.1 0.0 0.0 82.8 116.0 0.0 17.7 1.0 0.0 5.1 12.4 0.0 5.6 3.8 0.0 0.0 2.4 104.8 30.2 0.0 1.2 173.1 14.1 0.3 204.6 0.0 0.0 0.0 9.6 0.4 0.1 251.1 170.1 1.4 4.9 0.0 74.5 397.3 EIF2AK1 "HRI, KIAA1369" ENSG00000086232 "Eukaryotic translation initiation factor 2 alpha kinase 1" Q9BQI3 7 6022247-6059175 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Protein synthesis inhibitor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Cytotrophoblasts: 219.1;Erythroid cells: 422.0;Syncytiotrophoblasts: 371.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016496, CAB022082, HPA061675" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm Cytosol "CAB022082: , HPA016496: AB_1848057, HPA061675: AB_2684583" "unprognostic (7.15e-3)" "unprognostic (2.00e-2)" "unprognostic (1.45e-1)" "unprognostic (2.91e-1)" "unprognostic (6.70e-2)" "unprognostic (9.69e-3)" "prognostic unfavorable (6.99e-4)" "unprognostic (2.36e-1)" "unprognostic (2.54e-1)" "unprognostic (1.07e-2)" "unprognostic (1.48e-1)" "unprognostic (8.96e-2)" "unprognostic (2.53e-1)" "unprognostic (1.99e-1)" "unprognostic (5.45e-2)" "unprognostic (9.02e-2)" "unprognostic (1.06e-2)" 27.2 39.4 28.1 27.7 28.9 105.9 35.9 30.6 36.1 29.0 34.9 48.8 37.1 25.0 37.4 30.4 31.0 23.8 33.8 28.1 30.6 43.8 65.1 30.3 35.2 30.5 28.9 29.3 44.3 78.0 25.9 52.3 31.6 35.0 47.3 29.0 46.8 24.2 38.3 33.3 37.2 23.8 29.1 26.6 49.1 19.5 29.8 43.6 39.3 34.4 40.4 27.2 22.4 33.7 144.5 90.5 71.2 108.8 66.4 59.6 92.4 73.0 66.8 64.2 80.8 83.7 96.2 112.5 77.4 81.3 115.5 100.4 93.1 67.1 82.2 69.8 140.3 115.9 91.6 127.3 54.3 100.8 102.0 48.1 82.8 60.7 64.9 67.7 69.4 88.1 189.0 106.8 61.4 146.5 55.6 128.6 88.5 84.6 99.7 120.0 74.6 134.0 82.3 70.3 87.3 156.5 139.3 186.6 63.8 98.6 141.0 122.4 65.9 37.0 134.2 65.3 78.2 106.5 114.8 115.6 73.9 129.8 108.7 11.1 6.9 17.3 8.2 5.5 5.6 12.3 6.5 9.3 6.9 9.5 7.5 6.6 3.7 10.2 6.2 6.0 8.9 4.8 28.1 28.9 30.6 36.1 28.1 30.6 30.5 28.9 31.6 29.1 29.8 33.7 23.1 38.5 43.7 14.4 42.8 23.8 34.9 34.3 41.5 29.7 52.5 34.9 49.6 45.8 37.7 44.1 16.7 219.1 52.5 57.1 66.5 55.0 8.8 59.5 42.3 27.5 38.5 422.0 21.8 44.8 82.1 29.7 64.7 48.1 20.8 44.9 21.0 63.2 53.8 32.0 21.9 68.7 54.9 39.0 29.9 16.1 34.5 65.2 24.9 13.1 62.8 46.4 70.0 19.1 26.9 53.0 47.0 37.6 60.1 43.3 47.5 66.1 48.3 26.5 13.1 32.0 26.0 33.7 34.5 45.5 22.4 371.0 38.0 57.1 52.7 32.3 ELK3 "ERP, NET, SAP2" ENSG00000111145 "ETS transcription factor ELK3" P41970 12 96194375-96269824 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 170.7;Endothelial cells: 148.0;Hepatic stellate cells: 160.6;Respiratory ciliated cells: 103.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001600 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 13: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Mitochondria "HPA001600: AB_1078752" "unprognostic (3.11e-1)" "unprognostic (8.81e-3)" "unprognostic (6.38e-2)" "unprognostic (5.77e-2)" "unprognostic (7.18e-3)" "unprognostic (1.12e-1)" "unprognostic (1.15e-1)" "unprognostic (5.10e-3)" "unprognostic (7.39e-2)" "prognostic unfavorable (4.93e-4)" "unprognostic (2.29e-2)" "unprognostic (1.13e-1)" "unprognostic (1.20e-3)" "unprognostic (2.90e-3)" "unprognostic (1.61e-1)" "unprognostic (1.70e-1)" "unprognostic (2.05e-2)" 37.1 14.4 5.4 34.2 6.1 18.4 28.4 14.4 5.8 28.0 11.7 15.6 9.2 35.2 9.3 38.1 16.9 30.2 23.9 4.7 7.2 14.0 10.8 27.5 38.0 9.1 7.9 10.2 9.0 11.6 5.8 27.0 7.9 13.1 13.9 2.9 15.3 15.3 11.2 12.5 13.5 37.9 7.0 41.8 14.8 8.6 8.3 19.7 21.8 22.2 37.5 29.2 24.5 6.6 50.3 29.5 29.7 15.8 73.7 137.3 7.6 62.3 118.5 48.6 37.3 1.7 36.6 8.0 20.9 70.4 36.4 17.6 3.3 99.8 85.0 21.7 11.4 2.5 12.2 11.2 22.3 24.2 5.7 81.3 18.4 100.4 75.4 98.5 117.8 6.0 6.0 32.3 166.4 7.6 4.8 16.4 36.3 7.1 38.8 39.7 49.8 9.1 41.7 13.0 1.4 31.4 20.5 9.1 32.0 44.7 5.0 13.3 73.2 132.4 52.2 82.5 54.8 61.7 55.0 1.8 47.0 28.2 94.1 7.1 23.5 0.5 11.1 13.0 42.5 23.2 25.7 15.0 17.7 19.0 15.4 11.4 7.4 20.1 12.1 7.1 45.4 12.8 5.4 6.1 14.4 5.8 4.7 7.2 9.1 7.9 7.9 7.0 8.3 6.6 170.7 6.4 22.3 3.9 22.3 32.6 44.6 15.0 10.8 0.7 7.1 8.1 6.6 2.8 39.4 5.5 4.2 1.2 27.5 2.1 5.9 21.8 1.0 49.0 19.7 148.0 1.2 12.4 4.2 15.6 3.9 35.2 3.1 44.0 17.1 1.3 160.6 4.3 24.5 0.0 1.9 3.4 2.0 32.0 39.7 2.5 11.5 31.4 12.4 39.4 23.6 5.8 9.2 5.5 5.3 56.8 3.4 10.5 29.5 45.7 0.5 0.7 103.1 0.6 13.1 27.7 19.9 0.2 12.6 24.4 27.0 1.1 32.6 10.6 3.0 79.0 ELMO1 "CED-12, CED12, ELMO-1, KIAA0281" ENSG00000155849 "Engulfment and cell motility 1" Q92556 7 36852906-37449223 "Predicted intracellular proteins" "Apoptosis, Phagocytosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 228.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 236.7;Microglial cells: 519.0;Oligodendrocyte precursor cells: 284.0;Oligodendrocytes: 1412.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 129.9;JURKAT: 122.0;Karpas-707: 118.0;U-698: 141.7;U-937: 123.4" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (1.77e-2)" "unprognostic (8.29e-3)" "unprognostic (1.55e-1)" "unprognostic (1.19e-2)" "unprognostic (3.69e-1)" "unprognostic (4.09e-2)" "unprognostic (3.01e-2)" "unprognostic (3.53e-3)" "unprognostic (1.34e-1)" "unprognostic (1.71e-1)" "prognostic favorable (4.62e-4)" "unprognostic (3.59e-1)" "prognostic unfavorable (3.27e-5)" "unprognostic (1.65e-2)" "unprognostic (3.42e-1)" "unprognostic (1.07e-2)" "unprognostic (3.16e-3)" 27.5 14.5 77.5 32.4 131.5 59.4 21.9 95.1 108.2 14.9 24.3 11.8 6.6 7.8 4.5 10.9 10.4 21.2 16.6 82.9 88.5 6.9 28.0 28.9 49.2 131.7 108.9 13.4 13.2 4.9 12.0 38.1 124.2 10.8 13.0 12.9 9.4 9.9 7.2 10.1 19.1 15.9 89.5 56.4 9.0 6.5 126.1 29.4 82.0 16.6 51.4 18.7 15.5 228.3 0.2 4.1 7.6 0.0 0.0 0.0 16.4 0.2 0.1 0.0 0.0 0.2 0.0 129.9 2.2 0.0 1.0 0.5 0.0 0.0 0.0 72.7 4.7 94.6 0.3 0.0 0.0 60.5 38.0 1.6 0.0 0.0 0.0 0.0 49.8 122.0 1.5 118.0 0.0 0.8 69.8 84.0 19.4 0.2 0.0 77.5 10.1 72.3 0.2 0.0 8.5 40.3 0.3 24.1 0.5 27.3 0.1 43.3 14.4 0.2 1.4 0.3 0.6 98.8 90.1 141.7 21.1 123.4 6.0 49.9 52.8 164.1 33.2 45.7 33.8 49.8 52.1 36.6 78.2 39.7 47.1 36.3 107.0 41.6 40.6 40.1 47.8 55.6 77.5 131.5 95.1 108.2 82.9 88.5 131.7 108.9 124.2 89.5 126.1 228.3 60.4 0.0 4.8 10.4 53.3 5.0 4.5 0.0 3.4 13.7 2.0 2.8 3.5 7.2 0.6 0.0 0.0 1.5 26.8 0.4 0.0 0.2 1.0 1.8 2.4 44.6 3.6 24.6 236.7 1.1 26.7 14.6 0.0 1.1 34.9 6.9 37.1 15.4 20.4 0.0 106.7 0.9 0.0 50.7 58.3 1.5 6.2 44.8 7.2 519.0 34.6 1.1 41.2 284.0 1412.3 0.6 0.8 24.8 31.7 1.9 0.0 2.0 0.0 1.8 13.1 9.5 2.7 1.4 4.6 0.8 4.3 19.7 35.6 15.2 0.2 1.8 EMCN MUC14 ENSG00000164035 Endomucin Q9ULC0 4 100395341-100880126 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 11 "Adipocytes: 409.0;Endothelial cells: 261.7;Hepatic stellate cells: 175.3;Microglial cells: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HUVEC TERT2: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005928 Approved "Intracellular and membrane" NA NA 470000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA005928: AB_1078735" "unprognostic (8.01e-2)" "unprognostic (2.13e-4)" "unprognostic (1.36e-1)" "unprognostic (2.42e-1)" "unprognostic (2.96e-3)" "unprognostic (2.00e-2)" "prognostic favorable (1.03e-4)" "unprognostic (3.65e-1)" "unprognostic (5.94e-2)" "unprognostic (9.02e-2)" "unprognostic (2.39e-2)" "unprognostic (3.10e-2)" "prognostic favorable (2.25e-4)" "unprognostic (4.75e-3)" "unprognostic (2.36e-1)" "unprognostic (3.23e-1)" "unprognostic (9.75e-2)" 46.3 20.2 6.7 9.6 7.1 0.2 38.2 7.1 11.2 37.1 7.8 10.3 6.8 27.9 9.9 12.7 19.2 31.4 38.5 6.3 7.5 79.7 7.5 48.4 6.6 8.1 7.0 6.9 6.2 19.2 9.6 0.8 9.0 12.7 8.1 1.5 9.2 25.6 18.5 9.0 8.3 38.8 7.0 3.5 8.2 2.3 9.4 8.7 43.6 40.2 4.9 24.9 13.9 7.4 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.8 0.0 0.0 0.1 0.0 30.6 0.0 0.0 0.1 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 5.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.7 7.1 7.1 11.2 6.3 7.5 8.1 7.0 9.0 7.0 9.4 7.4 409.0 6.4 6.0 0.3 14.0 16.6 0.5 0.1 6.2 0.1 2.1 3.0 14.1 0.0 0.7 0.0 0.0 0.1 1.7 0.0 0.0 0.1 0.7 0.6 0.6 261.7 0.0 8.0 1.3 0.0 0.0 16.2 0.0 0.3 0.0 0.1 175.3 1.1 0.2 0.0 0.2 0.0 0.0 5.5 21.4 1.3 1.2 1.7 16.0 111.5 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.4 2.6 1.0 0.0 0.2 0.0 0.4 0.0 5.8 21.4 0.2 0.5 1.1 14.6 0.3 2.4 0.7 0.0 1.0 EMILIN1 "DKFZp586M121, gp115" ENSG00000138080 "Elastin microfibril interfacer 1" Q9Y6C2 2 27078615-27086403 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 64.5;Fibroblasts: 111.3;Hepatic stellate cells: 45.0;Leydig cells: 85.1;Peritubular cells: 167.3;Sertoli cells: 72.3;Smooth muscle cells: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 98.2;BJ hTERT+: 65.0;HHSteC: 99.0;HSkMC: 109.6;SH-SY5Y: 129.4;U-138 MG: 63.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002822 Supported "Secreted to extracellular matrix" NA NA 4300000 "Cluster 49: Eosinophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA002822: AB_1078738" "unprognostic (3.14e-1)" "unprognostic (2.44e-2)" "unprognostic (3.92e-2)" "unprognostic (3.42e-2)" "unprognostic (3.26e-2)" "unprognostic (1.46e-1)" "unprognostic (3.07e-1)" "unprognostic (2.89e-2)" "unprognostic (4.10e-3)" "unprognostic (3.07e-2)" "unprognostic (1.85e-1)" "unprognostic (7.97e-2)" "prognostic unfavorable (8.13e-9)" "unprognostic (8.96e-3)" "unprognostic (3.77e-2)" "unprognostic (1.20e-2)" "unprognostic (5.70e-3)" 55.5 55.7 6.9 47.0 7.1 1.9 43.6 6.4 7.1 139.8 4.6 223.5 24.9 206.3 7.4 23.3 129.2 35.4 68.9 5.9 7.5 55.5 42.4 100.7 11.7 13.0 7.6 172.4 21.2 1.4 26.9 16.2 9.5 96.4 7.9 0.3 17.5 52.1 10.3 19.1 72.0 50.3 8.3 118.1 87.6 16.9 10.4 2.4 29.7 2.6 2.2 142.9 70.2 8.6 0.9 0.7 5.9 0.9 35.8 49.0 1.1 98.2 65.0 20.7 29.7 0.5 0.8 0.6 0.9 56.6 0.1 0.9 0.2 0.2 3.8 3.1 1.3 1.8 0.5 43.9 99.0 1.5 27.0 109.6 0.1 14.2 0.0 0.2 0.2 1.3 1.0 0.9 4.3 1.1 0.9 28.8 3.2 0.5 0.7 15.6 1.3 1.2 0.0 0.4 1.6 129.4 0.3 0.5 1.1 0.4 0.4 2.5 11.9 63.6 2.0 7.6 0.4 1.7 1.8 1.1 0.7 1.3 17.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.2 0.0 6.9 7.1 6.4 7.1 5.9 7.5 13.0 7.6 9.5 8.3 10.4 8.6 5.2 0.0 0.5 6.5 0.4 3.3 0.2 0.0 0.0 0.6 0.8 7.1 2.9 1.5 0.0 0.0 0.0 1.6 0.6 0.2 0.0 0.4 0.6 1.9 64.5 6.3 0.0 4.0 0.2 0.4 1.5 111.3 0.5 1.3 4.5 0.2 45.0 1.0 6.4 0.0 0.3 0.3 0.0 2.5 5.8 10.0 85.1 4.1 10.6 8.4 0.5 3.6 0.0 0.5 0.3 0.8 0.1 167.3 0.8 0.2 0.5 1.0 0.0 1.1 72.3 35.3 52.4 0.6 0.4 0.4 3.1 2.9 1.3 10.7 0.1 0.1 EMP2 XMP ENSG00000213853 "Epithelial membrane protein 2" P54851 16 10528422-10580632 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 230.6" "Group enriched" "Detected in many" 7 "Alveolar cells type 1: 4163.5;Suprabasal keratinocytes: 1174.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "MCF7: 268.1;RT4: 182.0;SK-BR-3: 256.2;T-47d: 156.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014711, HPA070816" Approved Approved Nucleoplasm,Cytosol No Yes "Cluster 42: Non-specific - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm Cytosol "HPA014711: AB_1848147, HPA070816: " "unprognostic (1.75e-1)" "unprognostic (4.05e-2)" "unprognostic (3.45e-3)" "unprognostic (4.82e-1)" "prognostic unfavorable (2.23e-4)" "unprognostic (9.27e-2)" "unprognostic (8.90e-2)" "unprognostic (2.41e-2)" "unprognostic (4.40e-1)" "unprognostic (1.86e-1)" "unprognostic (6.24e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (2.85e-8)" "unprognostic (9.54e-2)" "unprognostic (2.73e-1)" "unprognostic (2.54e-2)" "unprognostic (9.52e-2)" 56.8 9.7 15.5 12.4 15.5 0.7 49.5 14.8 17.1 51.0 18.6 48.0 15.5 25.9 45.5 152.1 35.5 17.7 64.1 13.6 15.6 20.3 83.2 230.6 5.7 16.1 16.8 54.9 13.7 32.8 13.3 23.0 16.0 38.8 34.1 2.0 39.2 17.3 22.5 140.6 28.3 22.3 15.2 16.0 39.1 7.2 18.8 5.3 27.7 25.4 32.8 39.6 72.9 15.7 28.7 39.1 15.9 18.9 35.0 30.0 31.3 40.0 36.8 23.9 35.7 128.5 98.2 0.2 12.6 48.4 17.2 123.9 41.1 49.8 31.3 0.1 26.1 0.1 76.6 72.1 6.1 0.2 0.4 18.4 13.1 31.9 3.2 5.4 10.1 0.1 9.6 2.6 66.9 268.1 0.4 0.6 18.3 46.4 9.5 7.5 18.2 61.7 5.5 182.0 22.0 25.0 49.6 256.2 15.2 45.2 156.6 6.2 5.7 75.5 32.2 25.6 22.7 0.8 1.0 0.2 33.2 0.5 75.7 1.3 0.2 0.3 0.2 0.2 0.2 0.2 0.2 0.1 0.1 0.3 0.2 0.2 1.1 0.3 0.3 0.3 0.2 0.1 15.5 15.5 14.8 17.1 13.6 15.6 16.1 16.8 16.0 15.2 18.8 15.7 239.7 4163.5 368.4 13.1 3.1 356.9 137.9 172.2 111.0 2.3 105.0 94.0 53.1 100.1 255.8 42.3 0.0 74.2 3.1 119.5 0.0 3.8 8.0 78.8 30.9 183.9 104.9 0.0 0.7 67.0 17.8 152.7 46.4 51.9 36.7 68.7 161.0 235.1 10.1 0.0 0.6 207.8 81.4 19.6 136.5 9.3 190.7 17.0 87.2 41.2 33.6 5.7 0.0 22.6 0.6 32.9 158.4 276.1 1.6 86.0 21.0 0.2 142.8 2.2 52.6 256.3 129.3 5.7 12.9 319.5 1174.3 48.0 9.3 73.3 178.5 221.4 ENPEP "CD249, gp160" ENSG00000138792 "Glutamyl aminopeptidase" Q07075 4 110365733-110565285 "CD markers, Enzymes, Plasma proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 163.6;kidney: 90.0" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 663.2;Proximal tubular cells: 177.6;Sertoli cells: 157.8" "Cancer enriched" "Detected in many" 8 "renal cancer: 41.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.7;HEK 293: 7.5;MOLT-4: 1.8;SuSa: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005128 Enhanced NA NA 55000000 "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 45: Enterocytes - Digestion" "HPA005128: AB_1844795" "unprognostic (2.73e-3)" "unprognostic (2.84e-3)" "unprognostic (5.16e-3)" "unprognostic (3.48e-1)" "unprognostic (2.90e-1)" "unprognostic (8.74e-2)" "unprognostic (3.34e-2)" "unprognostic (1.03e-1)" "unprognostic (1.35e-2)" "unprognostic (1.22e-1)" "unprognostic (1.93e-1)" "unprognostic (9.47e-2)" "unprognostic (4.49e-3)" "unprognostic (3.43e-3)" "unprognostic (1.52e-2)" "unprognostic (8.46e-2)" "unprognostic (2.49e-3)" 11.6 2.2 0.4 1.5 0.5 0.1 4.8 0.4 2.5 1.6 1.8 1.2 36.6 12.9 4.1 1.7 2.3 4.4 4.3 0.6 0.5 90.0 29.0 4.6 0.8 0.9 0.8 1.2 1.3 45.2 1.2 15.5 0.7 1.8 0.8 0.0 1.1 1.2 2.3 0.7 163.6 10.6 0.5 9.2 1.2 0.5 0.4 4.4 5.0 8.9 0.3 2.6 1.6 0.8 0.0 0.2 0.0 0.0 0.1 0.1 2.7 0.4 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 1.8 0.3 0.3 0.1 0.0 0.1 0.0 0.3 0.0 0.3 0.1 0.1 0.0 1.3 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.4 2.5 0.6 0.5 0.9 0.8 0.7 0.5 0.4 0.8 10.7 0.0 2.0 1.6 1.1 1.7 0.1 0.0 0.0 0.0 0.2 0.1 3.9 0.0 0.3 11.0 0.0 37.0 0.0 1.5 17.6 0.0 0.5 3.1 40.7 2.2 1.8 0.0 7.3 0.0 3.5 15.4 0.0 2.3 0.0 0.0 1.4 31.4 2.7 0.0 2.9 28.4 2.0 1.0 1.9 0.2 0.6 1.1 0.0 1.0 0.0 0.0 1.0 0.0 0.8 0.0 31.6 0.4 0.1 0.2 663.2 177.6 1.7 0.0 157.8 0.8 54.1 0.0 0.2 0.1 1.0 58.6 1.9 0.5 42.1 0.1 EOMES TBR2 ENSG00000163508 Eomesodermin O95936 3 27715949-27722711 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Differentiation, Gastrulation, Immunity, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 8.4;lymphoid tissue: 15.0" "Cell type enhanced" "Detected in some" "dendritic cells: 43.6;Erythroid cells: 16.8;NK-cells: 93.7;T-cells: 31.5" "Cancer enhanced" "Detected in many" "testis cancer: 5.8" "Region enriched" "Detected in single" 13 "cerebellum: 8.4" "Group enriched" "Detected in many" 7 "gdT-cell: 16.5;MAIT T-cell: 26.2;memory CD8 T-cell: 19.5;naive CD8 T-cell: 11.9;NK-cell: 33.0" "Group enriched" "Detected in many" 107 "NK-cells: 33.0;T-cells: 26.2" "Cell line enhanced" "Detected in some" "HDLM-2: 7.4;JURKAT: 8.3;SCLC-21H: 3.9" "Region enriched" "Detected in many" 8 "olfactory bulb: 77.5" "Group enriched" "Detected in some" 27 "cerebellum: 30.2;olfactory bulb: 12.7" HPA028896 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Golgi apparatus, Cytosol" "HPA028896: AB_10601370" "unprognostic (1.53e-4)" "unprognostic (5.95e-3)" "unprognostic (3.01e-2)" "unprognostic (1.60e-4)" "unprognostic (4.13e-2)" "unprognostic (9.63e-4)" "unprognostic (4.29e-4)" "unprognostic (3.14e-3)" "unprognostic (1.24e-1)" "unprognostic (2.82e-2)" "unprognostic (9.96e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (9.45e-6)" "unprognostic (1.61e-1)" "unprognostic (5.09e-1)" "unprognostic (6.32e-3)" "unprognostic (1.49e-2)" 1.0 0.6 0.2 3.2 0.1 1.8 0.6 8.4 0.4 0.4 0.4 0.7 0.4 0.8 0.8 0.3 0.4 1.6 0.3 0.2 0.3 0.4 2.4 2.2 15.0 0.2 0.3 0.5 0.3 0.1 0.2 0.4 0.6 0.5 0.8 1.6 0.9 0.1 0.1 0.2 1.4 0.4 0.3 12.8 1.3 0.4 0.2 1.5 0.5 0.1 5.4 1.3 0.4 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 1.6 1.3 0.0 7.4 1.1 0.0 0.0 0.5 0.0 0.9 0.0 0.0 0.8 0.0 0.9 0.3 0.0 8.3 0.2 0.0 0.0 2.0 2.0 0.0 0.2 0.2 0.9 1.3 0.0 0.0 0.6 0.0 3.9 0.0 0.0 0.0 0.9 0.3 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 16.5 0.0 26.2 0.0 3.0 19.5 0.0 0.0 0.2 11.9 0.2 33.0 0.1 0.1 0.0 2.9 0.2 0.1 8.4 0.4 0.2 0.3 0.2 0.3 0.6 0.3 0.2 0.4 0.3 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.4 0.2 0.3 0.8 1.5 0.0 0.0 0.0 0.0 43.6 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 16.8 0.0 0.0 0.0 0.3 0.5 0.1 0.0 0.0 2.2 1.6 0.2 0.0 0.0 0.0 0.0 3.1 0.7 0.0 0.3 1.3 1.8 1.0 1.1 0.1 93.7 0.0 0.0 0.0 0.0 0.4 9.8 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.7 0.0 2.0 0.0 0.1 0.0 31.5 0.0 0.0 0.0 EPHB3 "ETK2, Hek2, Tyro6" ENSG00000182580 "EPH receptor B3" P54753 3 184561785-184582408 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Angiogenesis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 51.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 38.1;Breast myoepithelial cells: 50.8;Enteroendocrine cells: 71.5;Intestinal goblet cells: 43.3;Squamous epithelial cells: 44.3;Undifferentiated cells: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 28.8;HaCaT: 40.2;OE19: 28.3;SK-BR-3: 30.9;T-47d: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA007698, HPA008184, CAB034350" Enhanced NA NA 100000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB034350: AB_2262377, HPA007698: AB_1848205, HPA008184: AB_1848206" "unprognostic (2.94e-2)" "unprognostic (5.88e-2)" "unprognostic (2.17e-2)" "unprognostic (7.80e-2)" "unprognostic (1.52e-1)" "unprognostic (9.19e-2)" "unprognostic (8.35e-2)" "unprognostic (1.94e-1)" "unprognostic (5.51e-2)" "unprognostic (1.76e-1)" "unprognostic (7.42e-2)" "unprognostic (3.31e-1)" "prognostic unfavorable (7.88e-5)" "unprognostic (8.83e-3)" "unprognostic (3.03e-2)" "unprognostic (9.59e-3)" "unprognostic (2.10e-3)" 1.7 0.7 3.0 3.7 2.7 0.1 10.4 5.8 4.1 22.7 1.0 10.3 6.4 10.1 1.8 30.6 4.0 2.8 1.9 2.9 2.4 5.8 0.9 3.4 0.9 5.7 3.4 8.3 14.9 1.1 2.0 5.7 6.1 10.0 10.9 0.5 31.7 3.5 0.5 51.5 6.3 3.8 2.3 1.0 22.8 0.9 4.0 0.7 0.9 0.4 2.4 4.0 20.9 2.7 6.6 2.3 14.8 1.6 4.5 0.3 28.8 1.1 1.9 2.2 1.2 2.0 0.2 0.0 2.8 6.3 1.0 40.2 5.4 1.9 0.6 0.2 1.1 0.0 0.3 0.0 0.3 0.0 0.2 1.2 13.0 1.8 0.2 0.7 0.0 0.0 0.0 0.0 1.0 17.6 0.0 6.4 1.4 28.3 2.5 1.5 9.0 0.0 0.0 5.8 1.9 2.2 1.2 30.9 1.3 7.8 20.5 0.1 0.0 3.6 5.1 1.8 2.5 0.0 0.0 0.1 0.3 0.0 14.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 2.7 5.8 4.1 2.9 2.4 5.7 3.4 6.1 2.3 4.0 2.7 0.9 3.2 2.7 11.1 0.2 24.1 7.6 5.3 17.1 0.9 38.1 50.8 1.8 2.8 4.6 0.0 0.0 10.1 1.1 21.5 1.9 0.5 0.6 3.7 4.0 1.4 71.5 0.0 4.6 1.6 18.7 6.9 27.0 7.5 4.5 2.1 1.8 0.0 23.5 15.2 5.8 43.3 10.2 0.3 9.8 0.4 2.8 2.4 0.0 1.0 0.8 0.1 0.0 5.0 0.3 3.2 7.2 6.0 0.0 6.0 1.7 0.2 1.4 1.0 0.0 4.5 2.9 0.4 0.6 44.3 35.8 16.3 0.8 1.6 55.0 20.7 ERG "erg-3, p55" ENSG00000157554 "ETS transcription factor ERG" P11308 21 38380027-38661780 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 94.4;Endothelial cells: 105.5;Hepatic stellate cells: 69.9;Microglial cells: 88.1" "Cancer enriched" "Detected in all" 4 "prostate cancer: 18.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 138.3;MOLT-4: 47.7;REH: 151.5;TIME: 113.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018377, HPA046598" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "CAB018377: AB_675518, HPA046598: AB_2679715" "unprognostic (2.14e-1)" "prognostic unfavorable (6.18e-6)" "unprognostic (6.44e-3)" "unprognostic (8.64e-3)" "unprognostic (5.65e-2)" "unprognostic (1.91e-1)" "unprognostic (9.03e-4)" "unprognostic (4.30e-2)" "unprognostic (2.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (4.31e-3)" "unprognostic (3.88e-2)" "unprognostic (2.64e-2)" "unprognostic (5.63e-3)" 24.6 4.1 5.1 7.1 5.5 7.6 20.0 5.0 5.5 10.0 3.0 5.4 3.4 11.6 1.9 5.2 9.1 12.0 12.4 4.5 5.1 12.8 6.1 19.6 7.5 5.9 5.4 4.4 4.9 2.4 2.4 24.3 6.2 7.1 3.4 0.5 3.7 4.3 7.9 4.9 6.5 12.0 4.7 26.6 4.6 1.5 7.0 4.1 10.0 9.9 3.7 9.2 6.9 5.4 0.0 0.0 1.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.2 22.3 0.0 0.1 0.9 0.0 0.0 138.3 0.1 0.0 0.0 0.0 1.0 47.7 0.0 0.5 0.0 0.0 151.5 0.0 0.0 0.0 0.1 0.1 0.0 1.1 0.2 0.0 0.0 0.0 0.0 113.4 0.7 2.2 0.5 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.1 5.5 5.0 5.5 4.5 5.1 5.9 5.4 6.2 4.7 7.0 5.4 94.4 0.0 3.9 0.3 0.7 3.4 1.7 0.6 3.4 0.0 0.6 4.3 3.8 4.3 1.3 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.7 0.7 0.4 105.5 0.0 13.5 13.3 0.0 0.0 5.7 0.0 2.1 24.0 4.4 69.9 1.3 0.3 0.0 1.7 0.4 0.0 5.9 3.4 2.1 0.9 0.9 3.6 88.1 0.2 0.0 0.0 7.1 1.4 0.0 0.0 0.0 1.5 1.4 0.0 0.0 0.0 0.1 0.0 2.4 3.7 0.3 1.4 0.5 3.4 0.0 0.6 0.5 0.3 0.6 ERICH3 "C1orf173, DKFZp547I048, RP11-653A5.1" ENSG00000178965 "Glutamate rich 3" Q5RHP9 1 74568117-74673792 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 17.3;testis: 24.1" "Group enriched" "Detected in some" 4 "Early spermatids: 326.4;Endometrial ciliated cells: 139.8;Late spermatids: 326.9;Respiratory ciliated cells: 234.6" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028655, HPA072916" Approved NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 49: Ciliated cells - Cilium organization" "HPA028655: AB_10961002, HPA072916: " "unprognostic (4.49e-4)" "unprognostic (1.02e-2)" "prognostic favorable (1.56e-5)" "unprognostic (1.71e-2)" "unprognostic (5.94e-2)" "unprognostic (6.83e-2)" "unprognostic (6.53e-2)" "unprognostic (4.76e-2)" "unprognostic (8.84e-2)" "unprognostic (1.49e-2)" "unprognostic (1.54e-1)" "unprognostic (1.74e-4)" "unprognostic (9.21e-3)" "unprognostic (2.25e-1)" "unprognostic (2.02e-1)" "unprognostic (8.90e-2)" 0.0 2.5 3.1 0.0 3.5 0.0 0.8 0.2 5.4 5.4 0.0 0.0 0.0 1.0 0.0 0.0 17.3 0.0 0.0 3.4 1.8 0.0 0.0 2.7 0.2 0.0 0.3 0.1 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 24.1 3.2 0.6 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 3.5 0.2 5.4 3.4 1.8 0.0 0.3 0.0 0.0 3.2 0.2 0.0 3.2 3.1 3.6 0.3 0.0 0.0 0.0 0.0 3.5 2.8 0.3 0.6 0.0 28.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 326.4 139.8 1.0 0.4 3.5 0.0 56.8 0.0 0.0 0.5 0.0 3.2 1.3 0.0 0.0 0.1 0.0 0.0 51.8 0.0 0.0 0.0 0.0 326.9 3.1 0.7 0.0 1.0 0.0 0.1 1.0 24.6 3.2 0.0 0.0 3.8 0.0 0.6 0.0 0.0 234.6 0.5 6.6 0.0 0.1 32.9 1.5 0.0 0.0 0.1 0.3 0.1 0.0 0.3 ETFB ENSG00000105379 "Electron transfer flavoprotein subunit beta" P38117 19 51345169-51366388 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 493.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 1105.3;Proximal enterocytes: 710.7;Proximal tubular cells: 1118.7" "Cancer enhanced" "Detected in all" "liver cancer: 53.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 1693.9;OE19: 770.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018910, HPA018921, HPA018923" Supported Enhanced Mitochondria NA NA 170000 "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA018910: AB_1848280, HPA018921: AB_1848281, HPA018923: AB_1848282" "unprognostic (1.44e-1)" "prognostic favorable (6.45e-4)" "unprognostic (8.66e-2)" "unprognostic (3.08e-1)" "unprognostic (1.77e-1)" "unprognostic (3.94e-2)" "unprognostic (3.20e-1)" "unprognostic (6.93e-3)" "unprognostic (2.63e-2)" "unprognostic (7.79e-2)" "unprognostic (1.23e-1)" "unprognostic (4.75e-1)" "prognostic favorable (6.45e-5)" "unprognostic (2.19e-1)" "unprognostic (2.54e-1)" "unprognostic (4.83e-1)" "unprognostic (1.99e-1)" 159.1 171.5 121.1 44.0 134.4 70.2 115.3 134.8 145.5 55.7 123.0 97.6 136.3 48.9 16.9 140.7 53.3 62.7 387.8 112.8 120.6 144.5 493.6 50.4 58.2 129.8 124.8 55.2 81.9 106.3 73.1 39.0 125.7 55.2 41.2 24.1 172.2 37.9 280.7 79.0 129.7 31.7 119.9 64.5 90.0 53.6 132.4 81.4 70.3 280.3 36.9 65.6 69.0 137.0 118.9 304.3 41.3 113.9 129.4 150.4 65.6 82.4 61.0 63.5 63.1 257.3 192.1 121.5 80.2 129.8 33.8 104.0 83.3 171.1 19.2 182.0 323.3 98.1 188.9 1693.9 141.8 92.1 67.6 235.3 50.3 86.1 88.2 79.2 54.9 115.0 146.6 130.2 83.2 243.7 95.2 86.2 26.7 770.2 372.0 104.5 114.4 224.6 88.5 135.7 91.7 44.5 184.5 49.9 94.4 29.4 130.3 86.3 77.8 65.9 67.6 71.4 73.3 195.8 130.0 109.8 335.0 135.1 172.5 127.7 190.1 119.6 104.3 212.3 137.4 281.6 156.0 134.2 225.3 303.1 163.6 136.0 97.8 205.3 165.7 265.1 225.7 140.5 121.1 134.4 134.8 145.5 112.8 120.6 129.8 124.8 125.7 119.9 132.4 137.0 90.9 80.1 93.8 15.3 75.6 65.0 114.9 196.4 55.2 77.1 129.9 170.1 243.8 234.4 122.5 121.4 31.3 240.7 58.7 440.9 571.3 188.0 139.2 67.5 70.2 76.2 168.4 120.0 4.1 140.5 206.6 93.8 128.9 48.2 88.8 63.2 144.9 1105.3 217.5 43.7 4.2 335.2 158.7 147.7 73.4 354.4 107.5 86.9 286.4 5.6 95.2 158.8 50.4 7.1 18.9 155.4 339.4 114.3 69.9 74.9 710.7 1118.7 118.8 67.9 98.6 87.4 144.5 71.0 52.8 135.3 63.6 160.1 74.0 217.3 354.4 140.3 ETV4 "E1A-F, E1AF, PEA3" ENSG00000175832 "ETS variant transcription factor 4" P43268 17 43527844-43579620 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 23.3;Cholangiocytes: 17.2;Distal tubular cells: 17.6;Enteroendocrine cells: 14.9;Extravillous trophoblasts: 19.8;Syncytiotrophoblasts: 14.9" "Cancer enhanced" "Detected in all" "testis cancer: 80.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 177.7;Hep G2: 173.0;SK-MEL-30: 197.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005768 Approved Supported "Nucleoli rim,Mitotic chromosome" Yes No "Cluster 24: Salivary gland - Salivary secretion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoli rim" "Mitotic chromosome" "HPA005768: AB_1848294" "unprognostic (2.32e-1)" "unprognostic (7.33e-2)" "unprognostic (2.14e-1)" "unprognostic (2.51e-1)" "unprognostic (1.97e-2)" "unprognostic (3.14e-3)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.58e-2)" "unprognostic (5.34e-2)" "unprognostic (8.13e-2)" "unprognostic (7.05e-2)" "unprognostic (3.01e-1)" "unprognostic (7.79e-2)" "unprognostic (2.03e-1)" "unprognostic (7.08e-2)" "prognostic favorable (7.60e-4)" "unprognostic (1.69e-1)" 0.5 2.4 1.2 1.0 1.6 0.0 7.0 0.8 2.2 3.6 0.0 2.0 6.1 2.4 1.0 9.2 2.5 6.4 3.1 1.3 0.8 5.4 1.2 2.2 0.6 1.0 0.9 0.4 7.8 7.9 14.7 5.2 1.4 4.5 1.7 3.0 4.6 3.6 1.3 6.4 4.2 1.4 0.3 0.4 3.8 1.2 0.7 0.3 6.9 2.5 4.8 2.1 5.3 0.9 24.5 67.0 80.4 177.7 3.1 20.1 17.9 7.9 21.1 14.9 15.2 38.1 33.9 0.1 4.3 4.1 36.6 43.6 2.7 40.2 13.2 0.8 0.5 2.3 10.7 173.0 4.3 47.0 20.9 3.6 1.4 56.8 35.0 16.8 32.1 0.3 48.9 0.1 31.0 9.8 0.2 82.9 116.9 123.1 110.9 99.8 9.8 58.9 33.0 17.3 0.1 71.4 2.1 4.5 197.0 43.8 0.8 13.9 15.1 10.6 52.0 15.7 22.1 7.3 47.8 0.1 18.9 8.9 63.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 1.6 0.8 2.2 1.3 0.8 1.0 0.9 1.4 0.3 0.7 0.9 0.2 0.0 0.0 1.3 0.0 1.9 2.5 3.6 23.3 3.2 10.4 12.3 1.1 17.2 2.4 0.0 0.0 2.3 0.1 1.1 17.6 6.5 3.1 0.7 0.3 1.5 14.9 0.0 1.6 1.0 19.8 1.9 3.1 1.6 0.0 0.2 0.7 0.0 0.8 0.0 1.0 4.0 2.0 0.3 0.3 6.0 0.3 0.2 3.6 1.0 0.0 10.9 0.0 1.0 0.0 3.7 3.3 0.4 0.0 0.9 1.9 0.1 1.0 0.3 0.0 2.1 1.7 0.0 1.3 3.6 1.1 14.9 0.3 0.1 7.7 4.3 EVA1B "C1orf78, FAM176B, FLJ10647" ENSG00000142694 "Eva-1 homolog B" Q9NVM1 1 36322031-36324154 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 143.9;Extravillous trophoblasts: 250.3;Syncytiotrophoblasts: 161.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 23.3;BJ: 29.0;BJ hTERT+: 22.4;HSkMC: 20.4;NB-4: 41.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041928, HPA043537" Approved Approved Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA041928: AB_2677752, HPA043537: AB_2678538" "prognostic favorable (4.58e-4)" "unprognostic (5.66e-3)" "unprognostic (1.04e-3)" "unprognostic (3.20e-2)" "unprognostic (1.22e-2)" "unprognostic (4.00e-3)" "prognostic unfavorable (4.82e-4)" "unprognostic (1.45e-1)" "unprognostic (8.33e-2)" "unprognostic (1.48e-1)" "unprognostic (1.09e-1)" "unprognostic (2.60e-1)" "prognostic unfavorable (4.79e-5)" "unprognostic (1.87e-2)" "unprognostic (3.96e-2)" "unprognostic (1.39e-1)" "unprognostic (2.02e-1)" 26.8 19.4 5.5 3.4 5.4 2.0 35.8 5.5 6.4 41.8 7.5 19.8 2.5 34.0 0.6 12.2 21.9 1.3 19.9 5.0 5.9 39.2 8.5 26.1 1.9 6.8 6.4 30.2 7.8 1.9 9.4 9.0 6.0 29.0 0.4 0.0 28.7 2.9 5.7 24.0 15.8 1.6 7.0 37.6 14.2 7.5 6.6 0.5 33.9 1.0 0.5 22.0 30.1 5.7 0.7 2.7 1.6 3.0 7.9 23.3 6.8 29.0 22.4 5.4 6.3 0.2 2.1 0.0 8.5 9.2 1.0 0.2 0.2 1.1 1.1 3.3 6.0 3.6 0.6 1.3 17.4 0.1 0.6 20.4 0.0 6.9 0.3 0.9 8.7 0.1 1.4 1.0 3.6 0.2 0.1 41.7 1.7 0.0 10.4 1.5 0.3 7.1 4.6 0.0 0.1 3.9 2.8 1.1 13.3 1.1 0.0 2.7 12.7 7.9 0.0 10.5 2.7 0.3 0.0 0.1 2.9 1.8 7.1 4.0 0.9 0.0 0.2 0.3 0.6 0.0 0.3 0.5 0.5 0.0 0.0 0.0 1.7 1.6 0.1 0.0 1.2 0.1 5.5 5.4 5.5 6.4 5.0 5.9 6.8 6.4 6.0 7.0 6.6 5.7 82.8 0.0 0.0 2.3 6.2 16.2 19.3 7.3 0.0 0.0 143.9 90.6 2.2 1.5 5.1 7.3 0.0 54.7 8.4 0.3 1.9 20.2 7.1 9.4 88.4 53.9 0.0 0.8 0.0 15.2 250.3 56.6 0.0 15.2 4.5 15.7 84.9 0.9 48.7 0.0 0.0 0.1 6.1 41.3 28.8 24.8 50.7 30.4 12.4 5.6 10.2 14.1 4.1 0.0 0.1 28.9 1.1 48.5 7.9 56.6 0.4 7.7 5.6 0.9 26.3 7.8 98.4 8.4 3.3 0.7 12.4 161.3 9.7 58.2 0.5 30.3 EVI5 NB4S ENSG00000067208 "Ecotropic viral integration site 5" O60447 1 92508696-92792404 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 199.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027339 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus" Vesicles "HPA027339: AB_1848308" "unprognostic (1.23e-1)" "unprognostic (2.84e-1)" "unprognostic (4.29e-3)" "unprognostic (1.65e-1)" "unprognostic (4.94e-2)" "unprognostic (1.06e-1)" "unprognostic (5.13e-3)" "unprognostic (7.43e-2)" "unprognostic (1.12e-1)" "unprognostic (9.11e-2)" "unprognostic (9.04e-3)" "unprognostic (2.25e-1)" "unprognostic (6.15e-2)" "unprognostic (8.30e-2)" "unprognostic (5.40e-1)" "unprognostic (6.38e-2)" "unprognostic (2.35e-2)" 5.7 8.1 5.9 4.5 8.3 2.7 4.4 8.5 5.8 5.9 8.2 4.8 4.3 6.4 4.6 4.0 5.1 5.8 7.1 4.2 7.7 5.0 16.4 7.1 3.2 8.1 6.2 3.8 3.8 7.9 3.9 12.1 6.8 5.3 5.5 4.9 4.5 5.6 2.9 5.0 4.0 7.1 8.6 4.5 6.4 9.6 6.3 1.3 6.6 3.6 3.3 5.5 3.8 10.9 5.4 5.9 9.1 8.9 14.5 18.2 8.6 12.2 18.5 8.2 9.4 10.4 1.4 2.4 16.8 14.0 15.2 6.1 8.6 9.0 14.6 0.2 3.3 4.3 5.6 6.2 14.2 3.1 4.8 11.5 7.2 14.2 8.5 23.9 17.9 0.2 7.7 3.8 13.9 2.7 0.3 3.6 2.6 3.5 4.8 2.2 21.7 3.2 6.3 15.5 3.4 7.0 14.4 7.4 16.6 9.8 3.6 7.1 11.8 9.1 6.6 12.2 8.1 5.5 3.4 3.8 6.0 5.0 7.6 0.9 2.7 2.8 0.1 1.9 0.0 1.2 0.1 0.0 1.3 1.2 0.0 0.0 3.4 0.1 2.9 0.8 0.0 0.4 5.9 8.3 8.5 5.8 4.2 7.7 8.1 6.2 6.8 8.6 6.3 10.9 27.2 60.9 29.9 91.4 18.7 43.5 29.3 23.0 18.2 24.5 20.5 17.7 51.8 22.8 32.3 16.5 25.0 48.4 7.5 22.9 17.6 27.9 3.0 67.8 39.4 31.2 22.1 11.4 158.4 29.9 26.0 42.5 42.3 26.2 13.3 21.9 43.2 52.4 32.2 30.3 149.3 27.0 14.2 54.0 27.0 5.8 28.3 45.1 26.6 114.3 48.9 28.5 5.2 112.6 199.6 68.4 19.3 54.2 28.8 28.1 21.8 20.1 46.9 25.4 13.1 51.4 56.4 37.4 42.4 21.2 50.0 65.5 5.5 60.9 20.0 32.1 EXOC3L1 "EXOC3L, FLJ35539, FLJ35587" ENSG00000179044 "Exocyst complex component 3 like 1" Q86VI1 16 67184379-67190185 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 44.7" "Cell type enhanced" "Detected in many" "Adipocytes: 26.4;Endothelial cells: 19.6;Granulosa cells: 20.8;Hepatic stellate cells: 28.9;Leydig cells: 15.5;Peritubular cells: 18.4;Theca cells: 32.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.7;HUVEC TERT2: 3.5;SCLC-21H: 6.4;SuSa: 2.1;TIME: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA029574 Uncertain Approved "Vesicles,Plasma membrane" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" "HPA029574: AB_10602495" "unprognostic (1.15e-2)" "unprognostic (4.91e-2)" "unprognostic (6.87e-3)" "unprognostic (2.09e-3)" "unprognostic (2.33e-1)" "unprognostic (2.46e-2)" "unprognostic (6.77e-2)" "unprognostic (3.98e-2)" "unprognostic (1.55e-1)" "unprognostic (1.26e-2)" "unprognostic (6.48e-3)" "unprognostic (2.88e-1)" "unprognostic (6.64e-3)" "unprognostic (3.40e-1)" "unprognostic (1.23e-1)" "unprognostic (3.26e-1)" "unprognostic (1.35e-1)" 6.4 4.6 0.5 1.8 0.5 0.0 4.1 1.0 0.8 2.6 0.0 1.6 0.9 2.8 0.1 1.3 1.8 1.1 5.4 0.5 0.5 7.3 2.1 10.0 1.4 0.8 0.2 3.6 1.6 0.8 2.0 5.9 1.1 2.4 0.4 0.2 1.6 0.6 2.1 1.2 1.7 0.9 0.1 44.7 1.5 2.1 0.4 0.1 7.1 0.8 0.2 1.7 1.3 0.1 0.1 0.0 0.7 0.2 0.0 0.0 1.7 0.3 0.0 0.0 0.0 0.8 0.1 0.0 1.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 3.5 0.4 0.3 0.0 0.1 0.1 0.2 0.0 0.2 0.0 0.4 0.8 0.7 0.1 0.0 0.1 6.4 0.8 0.8 0.1 0.0 2.1 0.6 0.0 2.5 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.5 0.5 1.0 0.8 0.5 0.5 0.8 0.2 1.1 0.1 0.4 0.1 26.4 0.0 0.0 0.3 0.3 0.9 2.1 2.8 5.7 1.5 3.0 5.2 1.6 0.0 0.4 3.7 0.0 0.6 0.2 4.6 7.9 1.0 2.0 0.1 0.3 19.6 1.2 2.7 0.1 3.7 4.3 2.6 1.5 0.4 0.0 20.8 28.9 1.4 0.8 3.3 0.3 3.4 2.0 1.9 0.2 5.5 15.5 1.8 0.0 1.0 4.0 0.3 0.0 1.0 0.0 0.6 3.1 18.4 0.0 0.4 8.9 0.2 0.3 0.9 0.0 0.3 1.1 4.0 8.6 1.2 2.0 0.8 0.2 32.5 2.7 1.6 EXOC3L2 "FLJ36147, XTP7" ENSG00000283632 "Exocyst complex component 3 like 2" 19 45212370-45245407 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "kidney: 19.0;thyroid gland: 17.9" "Group enriched" "Detected in some" 4 "Adipocytes: 15.3;Endothelial cells: 17.7;Hepatic stellate cells: 51.4;Theca cells: 21.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HEL: 19.1;K-562: 16.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041595, HPA061110" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Nucleoplasm, Golgi apparatus, Cytosol" "HPA041595: AB_10794521, HPA061110: AB_2684431" 4.3 8.3 0.3 2.1 0.6 1.6 2.9 0.5 0.4 4.0 1.6 2.7 2.4 4.9 0.4 1.9 2.8 2.3 2.3 0.4 0.3 19.0 2.7 2.7 1.1 0.7 0.5 0.9 2.7 3.3 5.0 0.4 0.5 5.2 0.7 0.1 1.8 2.2 0.9 2.1 3.2 1.9 0.3 8.3 2.9 3.3 0.4 0.4 17.9 0.3 0.5 3.2 2.4 0.7 0.1 0.3 2.5 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.3 0.1 2.2 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.1 19.1 0.6 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 16.6 0.2 0.0 0.2 0.0 0.0 0.1 0.1 0.5 1.1 0.0 0.1 0.0 0.2 0.3 0.0 0.1 0.1 0.1 1.0 0.1 0.3 0.6 0.8 1.5 0.2 0.1 0.2 0.1 0.0 0.1 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.5 0.4 0.4 0.3 0.7 0.5 0.5 0.3 0.4 0.7 15.3 0.0 1.3 0.7 0.7 0.4 0.3 0.0 0.0 0.7 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 17.7 0.0 0.0 1.5 0.0 0.0 0.5 0.0 0.2 0.0 0.4 51.4 0.3 0.0 0.0 1.1 0.6 0.0 1.6 0.0 0.0 1.8 2.8 0.0 0.0 0.1 0.2 2.1 0.5 0.7 0.0 0.0 1.9 0.1 0.2 0.1 0.1 0.0 0.2 0.0 0.3 0.6 0.4 6.2 0.2 0.9 0.0 0.1 21.2 0.0 0.3 F11 FXI ENSG00000088926 "Coagulation factor XI" P03951 4 186266189-186289681 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 243.2" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 27.6;Hepatocytes: 75.7" "Cancer enriched" "Detected in some" 13 "liver cancer: 16.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "Hep G2: 6.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA039808 Approved Vesicles "Secreted to blood" NA NA 4400000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA039808: AB_2676693" "unprognostic (1.28e-1)" "unprognostic (3.15e-1)" "prognostic favorable (3.29e-5)" "unprognostic (1.88e-1)" "unprognostic (2.08e-1)" "unprognostic (2.11e-1)" "unprognostic (1.85e-3)" "unprognostic (2.91e-2)" "unprognostic (7.65e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.5 0.2 0.0 0.2 17.1 0.2 0.1 0.0 0.0 13.1 0.0 0.2 0.0 27.6 243.2 8.4 0.0 0.0 0.3 0.3 58.9 0.0 0.2 0.0 0.1 0.0 0.1 0.7 0.0 0.2 0.7 0.0 8.7 0.0 0.0 0.1 0.8 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.2 0.0 0.0 0.3 0.1 0.0 0.3 0.0 0.0 0.0 27.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.3 2.5 1.8 0.0 0.0 0.2 0.3 11.7 2.3 0.0 0.0 0.0 0.1 0.0 5.3 0.6 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 75.7 0.0 0.0 0.6 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 2.1 0.0 0.0 0.0 0.0 1.1 5.5 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 F3 "CD142, TF" ENSG00000117525 "Coagulation factor III, tissue factor" P13726 1 94529173-94541759 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Blood coagulation, Hemostasis" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 902.0;Exocrine glandular cells: 464.1;Pancreatic endocrine cells: 1755.7;Peritubular cells: 530.7;Urothelial cells: 497.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 1062.0;HaCaT: 490.7;HBEC3-KT: 1270.5;U-2197: 473.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009438, HPA049292, HPA069132" Uncertain Approved Vesicles "Secreted to blood" NA NA 603000 "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "CAB009438: AB_668005, HPA049292: AB_2680701, HPA069132: AB_2686092" "unprognostic (3.86e-2)" "unprognostic (1.19e-1)" "unprognostic (8.04e-2)" "unprognostic (1.64e-1)" "unprognostic (2.69e-2)" "unprognostic (1.23e-3)" "unprognostic (4.93e-2)" "unprognostic (8.00e-2)" "unprognostic (5.88e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.07e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.02e-8)" "unprognostic (4.84e-2)" "unprognostic (4.08e-1)" "unprognostic (1.23e-1)" "unprognostic (1.08e-1)" 118.2 21.3 53.1 28.8 69.9 4.1 70.1 53.2 74.4 48.0 44.1 52.2 36.8 61.1 44.2 41.3 89.9 59.6 36.8 54.0 62.7 18.0 5.1 59.8 12.9 77.7 62.6 114.8 96.5 17.2 81.2 133.4 57.1 56.8 42.1 72.6 93.3 60.4 7.6 56.0 47.3 10.7 60.8 7.2 42.6 34.6 62.0 5.6 62.6 9.9 14.9 65.4 73.0 55.4 1062.0 1.8 2.2 0.5 108.0 53.1 57.2 147.0 87.6 155.4 167.9 18.6 220.6 0.0 73.3 183.5 33.4 490.7 13.2 1270.5 254.4 0.9 1.6 0.0 35.0 3.3 35.9 0.7 0.6 91.9 28.2 73.8 356.5 293.7 1.1 1.1 0.9 0.8 110.0 1.8 1.5 22.3 9.8 6.8 2.2 1.2 10.3 0.5 19.8 3.2 1.3 2.6 117.4 48.3 3.6 29.6 1.3 13.9 0.3 93.7 2.5 473.0 44.6 0.9 1.3 0.9 71.9 5.7 3.8 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 53.1 69.9 53.2 74.4 54.0 62.7 77.7 62.6 57.1 60.8 62.0 55.4 9.4 131.4 243.3 196.6 0.7 16.3 902.0 359.6 2.2 3.6 29.6 20.4 26.4 18.6 380.3 14.7 0.0 16.5 0.6 20.9 0.0 133.5 8.6 61.3 125.0 13.2 13.1 0.0 0.4 464.1 6.0 125.3 23.0 123.0 2.5 38.1 7.5 0.4 6.1 3.3 4.6 70.3 65.1 2.8 5.2 14.5 281.1 9.1 3.6 45.9 2.1 340.6 0.0 15.6 1.2 1755.7 15.5 530.7 1.2 121.6 10.1 0.4 92.0 16.1 6.6 39.3 76.7 1.7 4.4 6.4 7.5 7.7 7.3 7.9 14.3 497.9 F5 ENSG00000198734 "Coagulation factor V" P12259 1 169511951-169586588 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "choroid plexus: 142.8;liver: 176.2;placenta: 46.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 74.4;Cytotrophoblasts: 82.7;Hepatocytes: 253.4;Syncytiotrophoblasts: 59.5" "Cancer enriched" "Detected in many" 7 "liver cancer: 69.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "classical monocyte: 4.1;eosinophil: 8.1;neutrophil: 7.0;T-reg: 6.2" "Group enriched" "Detected in many" 13 "granulocytes: 8.1;monocytes: 4.1;T-cells: 6.2" "Group enriched" "Detected in some" 23 "Hep G2: 32.8;OE19: 125.5" "Group enriched" "Detected in many" 5 "basal ganglia: 2.7;hippocampal formation: 6.6;pons and medulla: 4.4;thalamus: 5.4" "Group enriched" "Detected in all" 7 "amygdala: 39.9;basal ganglia: 35.0;cerebral cortex: 67.9;hippocampal formation: 61.4;olfactory bulb: 27.6" HPA002036 Approved "Golgi apparatus" "Secreted to blood" NA NA 7670000000 13000000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "HPA002036: AB_1078787" "unprognostic (3.67e-2)" "unprognostic (2.77e-4)" "unprognostic (5.42e-2)" "unprognostic (2.56e-4)" "unprognostic (2.03e-1)" "unprognostic (2.39e-4)" "unprognostic (3.46e-3)" "unprognostic (9.25e-3)" "unprognostic (2.02e-1)" "unprognostic (8.99e-3)" "unprognostic (6.55e-3)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "prognostic unfavorable (3.39e-4)" "unprognostic (7.15e-2)" "unprognostic (3.41e-1)" "unprognostic (4.31e-1)" 1.1 0.0 0.3 3.2 1.4 3.7 0.6 4.4 1.3 0.1 142.8 0.3 0.9 0.1 0.2 0.2 3.5 17.6 2.7 4.4 1.6 1.5 176.2 0.9 2.2 1.9 2.2 0.0 0.8 0.0 1.6 46.9 2.4 1.3 0.6 1.0 6.2 0.0 0.2 1.3 0.3 1.1 0.8 1.8 4.9 0.5 2.2 0.5 0.4 0.2 2.3 3.8 0.1 4.2 0.0 0.6 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.2 1.5 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 32.8 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 125.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 4.1 8.1 0.0 0.2 0.0 0.0 1.4 0.2 0.4 0.0 0.3 0.0 7.0 0.0 0.0 0.0 6.2 1.1 0.3 1.4 4.4 1.3 4.4 1.6 1.9 2.2 2.4 0.8 2.2 4.2 0.0 3.2 0.6 1.6 0.7 0.1 6.1 0.0 0.0 0.3 0.7 0.3 9.4 74.4 1.9 0.0 2.1 82.7 0.1 0.3 0.0 2.4 2.4 0.9 0.0 2.4 25.2 0.0 5.4 0.2 2.3 5.3 4.1 0.2 0.0 2.8 3.6 253.4 5.3 0.0 2.6 0.1 0.0 12.3 0.4 0.3 0.0 7.1 3.6 0.0 18.2 1.0 2.1 0.5 1.0 1.9 0.0 0.0 0.1 1.8 0.0 0.2 3.1 0.1 0.0 2.4 0.2 0.5 0.5 0.0 0.0 59.5 2.5 0.0 0.0 11.8 FA2H "FAAH, FAXDC1, FLJ25287, SPG35" ENSG00000103089 "Fatty acid 2-hydroxylase" Q7L5A8 16 74712955-74774831 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 183.9;stomach 1: 61.1" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 85.1;Oligodendrocyte precursor cells: 61.3;Oligodendrocytes: 307.9;Paneth cells: 75.2;Urothelial cells: 192.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 38.1;HAP1: 48.6;JURKAT: 89.8;OE19: 61.5;SK-BR-3: 28.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056614, HPA077840" Approved Uncertain "Nuclear membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 70: Brain - Nervous system development" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear membrane" "HPA056614: AB_2683191, HPA077840: AB_2686858" "unprognostic (1.33e-1)" "unprognostic (4.97e-2)" "unprognostic (9.19e-2)" "unprognostic (1.08e-1)" "unprognostic (1.60e-1)" "unprognostic (5.85e-2)" "unprognostic (1.48e-2)" "unprognostic (2.47e-2)" "unprognostic (1.82e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (3.74e-4)" "unprognostic (6.01e-2)" "prognostic favorable (5.01e-6)" "unprognostic (1.50e-1)" "unprognostic (1.76e-1)" "unprognostic (1.83e-2)" "unprognostic (2.11e-3)" 0.3 0.3 41.7 4.3 89.1 0.3 2.8 77.9 63.0 1.9 11.7 21.2 10.3 0.2 2.2 7.9 1.8 17.8 0.3 46.1 56.1 8.2 0.2 1.4 0.7 129.2 79.6 0.0 8.4 10.1 0.6 0.7 106.0 1.9 19.4 0.4 11.0 0.7 0.0 8.5 14.4 1.1 65.2 0.5 61.1 2.9 75.2 4.7 2.0 0.1 5.9 26.3 2.2 183.9 9.2 38.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.5 0.0 20.8 21.0 0.0 0.2 0.0 2.0 3.6 48.6 0.6 0.1 0.0 1.6 0.0 2.7 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 89.8 0.0 0.0 0.0 15.2 0.8 0.0 0.9 61.5 2.1 0.0 0.0 1.6 23.4 15.6 6.5 0.0 0.0 28.8 0.0 1.3 8.6 0.0 0.0 0.0 0.1 0.0 0.2 1.4 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.7 89.1 77.9 63.0 46.1 56.1 129.2 79.6 106.0 65.2 75.2 183.9 0.0 0.0 1.3 1.0 2.6 0.5 11.1 8.5 1.8 0.0 5.0 3.3 0.2 8.6 14.6 0.0 0.0 0.5 0.2 43.0 7.9 13.5 10.8 2.4 0.5 0.2 6.7 0.0 0.7 14.2 0.2 1.1 85.1 4.5 0.0 0.1 0.0 0.0 0.1 0.0 0.9 34.8 4.1 0.0 0.0 4.0 0.0 0.2 3.6 0.0 0.0 0.0 0.0 61.3 307.9 38.4 75.2 0.4 6.2 22.9 17.6 0.2 10.5 0.0 0.0 0.0 0.6 2.4 3.3 12.4 0.9 0.1 0.2 0.0 15.3 192.8 FABP3 "FABP11, H-FABP, MDGI, O-FABP" ENSG00000121769 "Fatty acid binding protein 3" P05413 1 31365253-31376850 "Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 14 "heart muscle: 5666.1;skeletal muscle: 2202.5;tongue: 1442.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 629.8;Cardiomyocytes: 2495.2;Distal tubular cells: 452.0;Proximal tubular cells: 703.6" "Cancer enhanced" "Detected in all" "renal cancer: 92.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "ASC TERT1: 215.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017830, HPA055754" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Focal adhesion sites" NA NA 1640000 3000000 "Cluster 22: NK-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "Focal adhesion sites" "Golgi apparatus, Plasma membrane" "CAB017830: , HPA055754: AB_2682909" "unprognostic (2.07e-2)" "unprognostic (2.50e-2)" "unprognostic (1.32e-3)" "unprognostic (1.73e-2)" "unprognostic (2.05e-1)" "unprognostic (1.62e-1)" "unprognostic (6.07e-3)" "unprognostic (1.04e-1)" "unprognostic (6.86e-2)" "unprognostic (1.18e-1)" "unprognostic (2.85e-1)" "unprognostic (1.67e-1)" "prognostic favorable (1.54e-7)" "unprognostic (5.80e-3)" "unprognostic (3.45e-1)" "unprognostic (7.38e-3)" "unprognostic (9.76e-3)" 31.4 63.5 33.7 2.1 39.2 1.6 95.4 42.3 51.5 40.4 14.8 16.3 0.8 93.9 6.4 9.5 37.2 3.7 5666.1 52.0 37.3 229.8 6.6 26.4 3.4 50.5 38.3 20.3 2.2 0.3 9.0 2.8 55.2 48.9 4.8 17.8 46.5 52.2 2202.5 16.3 7.5 44.2 31.4 28.8 60.3 15.3 36.1 2.3 6.8 1442.4 1.4 12.5 32.5 36.8 1.0 0.4 8.8 1.1 50.6 215.0 2.0 2.6 17.3 0.3 6.6 1.3 1.9 1.6 17.8 5.2 0.3 2.1 2.5 0.0 0.5 0.8 3.7 1.8 2.7 5.3 2.2 1.7 0.5 16.9 0.0 3.9 0.0 2.5 0.0 1.4 2.2 0.5 2.2 0.5 0.7 1.5 11.4 0.9 3.1 0.4 5.7 0.6 4.1 0.7 2.1 0.5 1.5 0.7 28.4 13.2 0.9 3.1 1.7 1.0 1.0 6.0 1.3 1.0 2.3 1.3 2.9 1.5 1.7 0.0 0.1 0.0 0.2 0.2 0.2 0.2 0.1 0.3 0.1 0.2 0.1 0.4 0.0 0.2 0.1 0.1 0.1 0.1 33.7 39.2 42.3 51.5 52.0 37.3 50.5 38.3 55.2 31.4 36.1 36.8 4.9 0.0 1.7 2.9 7.7 3.6 1.5 0.4 0.0 6.1 629.8 13.2 2495.2 2.8 1.3 27.6 2.1 3.8 2.1 0.4 452.0 0.4 2.5 0.4 0.5 25.6 0.0 0.0 16.1 0.4 1.4 67.2 1.1 3.1 1.3 43.8 2.2 0.1 114.7 8.4 14.6 0.1 0.0 27.8 10.3 5.4 6.8 19.1 8.8 3.7 0.0 2.6 0.0 3.5 8.9 0.3 12.3 7.9 0.1 6.8 0.1 703.6 1.5 10.2 0.0 14.9 40.7 2.9 0.2 0.2 3.0 1.6 5.1 97.9 0.3 36.5 FAH ENSG00000103876 "Fumarylacetoacetate hydrolase" P16930 15 80152490-80186946 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 301.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 266.8;Proximal tubular cells: 305.5" "Cancer enhanced" "Detected in all" "liver cancer: 23.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 34.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 316.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041370, HPA044093" Enhanced Approved Nucleoplasm,Cytosol NA NA 220000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA041370: AB_2677438, HPA044093: AB_2678806" "unprognostic (3.15e-1)" "unprognostic (5.65e-2)" "unprognostic (1.64e-1)" "unprognostic (6.16e-2)" "unprognostic (2.33e-3)" "prognostic unfavorable (8.51e-4)" "unprognostic (1.19e-2)" "unprognostic (5.83e-2)" "unprognostic (2.51e-2)" "unprognostic (5.21e-2)" "unprognostic (1.80e-1)" "unprognostic (1.23e-1)" "unprognostic (2.17e-2)" "unprognostic (4.21e-2)" "unprognostic (2.99e-1)" "unprognostic (2.93e-1)" "unprognostic (8.98e-2)" 99.2 65.4 16.0 7.0 17.1 20.0 59.0 16.6 21.1 19.2 15.1 13.8 14.6 19.3 50.4 15.2 23.0 9.7 20.3 16.3 18.8 65.0 301.5 20.0 5.7 17.9 19.6 26.4 9.9 18.4 16.8 7.8 16.9 16.6 11.9 1.6 14.8 13.6 31.0 10.9 16.8 13.5 17.2 19.1 14.2 20.8 17.4 6.7 14.5 27.7 5.8 16.4 15.8 17.5 20.1 34.4 13.5 17.0 60.2 62.2 32.9 24.3 56.8 26.2 22.3 22.0 35.9 0.4 39.0 52.6 36.8 29.1 46.8 59.6 25.1 12.5 28.5 166.6 18.0 112.1 316.6 79.6 88.8 107.5 37.1 22.9 39.7 84.2 37.4 38.3 71.1 35.7 50.3 31.0 22.3 42.0 9.9 15.5 37.6 12.2 19.3 123.4 77.0 25.2 0.7 8.3 27.4 76.7 77.9 21.6 58.3 55.0 126.1 46.8 30.0 25.5 42.7 32.7 69.5 13.8 99.6 187.5 26.9 34.5 18.8 3.3 9.6 8.1 2.3 0.1 2.4 6.0 25.3 0.1 3.1 2.7 1.3 5.7 8.4 1.9 2.5 9.7 16.0 17.1 16.6 21.1 16.3 18.8 17.9 19.6 16.9 17.2 17.4 17.5 3.0 3.2 13.8 9.8 4.1 6.8 17.5 30.8 15.4 0.4 19.1 13.7 15.5 21.5 12.5 33.1 0.0 37.9 4.9 9.3 52.8 9.3 7.5 3.0 16.2 3.2 4.2 24.4 0.4 3.5 14.1 16.6 3.6 4.0 41.9 6.3 8.9 266.8 72.5 0.0 2.5 13.0 24.4 21.4 6.6 13.5 9.9 30.5 19.6 1.0 5.7 7.3 3.1 2.5 0.6 4.5 12.8 7.9 5.2 9.7 54.1 305.5 5.3 0.4 0.0 9.2 11.2 1.5 2.1 18.2 5.7 22.0 7.7 8.7 22.4 16.4 FAM114A1 Noxp20 ENSG00000197712 "Family with sequence similarity 114 member A1" Q8IWE2 4 38867677-38945739 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 3.6" "Group enriched" "Detected in many" 6 "dendritic cells: 2.6;granulocytes: 2.4;monocytes: 3.6" "Cell line enhanced" "Detected in many" "ASC TERT1: 204.7;BJ hTERT+: 244.1;fHDF/TERT166: 273.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067948, HPA069104, HPA069701" Uncertain Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" No No 96000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" Nucleoplasm "HPA067948: AB_2685931, HPA069104: AB_2686087, HPA069701: AB_2686175" "unprognostic (2.13e-3)" "unprognostic (4.68e-2)" "unprognostic (1.94e-1)" "unprognostic (4.66e-2)" "unprognostic (9.40e-3)" "unprognostic (6.77e-2)" "unprognostic (2.54e-1)" "unprognostic (2.31e-2)" "unprognostic (4.88e-2)" "unprognostic (1.55e-1)" "unprognostic (3.06e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (3.63e-6)" "unprognostic (1.31e-1)" "unprognostic (1.34e-1)" "unprognostic (2.39e-2)" "unprognostic (3.44e-3)" 28.4 48.1 7.9 23.6 11.8 2.0 20.2 7.8 9.2 48.4 23.7 34.6 22.9 29.2 17.8 35.1 19.5 36.4 23.7 9.9 11.4 11.8 54.2 21.2 8.9 13.7 12.5 41.5 25.6 22.4 18.5 35.6 11.2 35.5 33.7 3.1 61.2 27.8 16.6 15.6 24.4 61.7 9.0 8.8 34.4 12.5 12.1 4.3 17.6 22.7 19.5 35.6 26.4 13.4 43.5 30.7 18.5 21.9 197.4 204.7 6.1 167.9 244.1 69.7 105.8 8.1 33.0 0.0 23.0 273.8 118.8 11.9 0.1 53.7 80.1 0.2 4.6 3.1 30.3 40.6 70.6 0.1 5.8 122.1 17.0 101.2 23.3 157.2 101.4 0.1 3.4 0.2 102.9 11.0 0.1 2.3 3.8 18.3 15.6 0.8 90.9 3.2 23.4 8.7 0.7 9.4 33.8 0.7 33.8 42.8 20.8 3.8 156.3 75.4 34.8 95.3 39.5 0.7 0.2 0.3 123.3 3.3 63.0 0.6 3.2 0.0 0.1 3.6 0.0 0.4 0.1 0.1 2.6 0.1 0.1 0.1 2.4 0.0 1.4 0.3 0.0 0.9 7.9 11.8 7.8 9.2 9.9 11.4 13.7 12.5 11.2 9.0 12.1 13.4 28.1 16.0 13.2 5.9 2.2 12.2 47.4 43.7 15.4 0.3 29.9 21.2 17.2 14.3 56.0 7.3 0.0 2.2 0.2 46.8 9.8 45.6 1.0 17.5 88.6 35.2 15.7 3.6 1.0 61.0 47.0 94.9 35.7 39.1 1.3 30.4 31.1 68.3 16.1 0.0 1.8 78.7 83.4 7.2 15.0 6.3 110.9 8.7 21.4 17.8 6.4 12.2 0.0 14.6 31.0 47.6 41.6 116.2 8.5 92.6 39.0 11.7 47.8 1.2 19.7 49.4 44.3 1.2 5.5 23.6 10.2 3.4 3.1 94.1 32.0 82.7 FAM120A "C9orf10, KIAA0183, OSSA" ENSG00000048828 "Family with sequence similarity 120A" Q9NZB2 9 93451685-93566112 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019734, HPA055800" Approved Enhanced Cytosol NA NA 12000 "Cluster 35: T-regs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA019734: AB_1848369, HPA055800: AB_2682925" "unprognostic (5.92e-2)" "unprognostic (2.15e-1)" "unprognostic (1.45e-1)" "prognostic favorable (5.03e-4)" "unprognostic (3.36e-1)" "unprognostic (2.33e-2)" "unprognostic (8.93e-2)" "unprognostic (5.84e-2)" "unprognostic (3.06e-1)" "unprognostic (1.07e-1)" "unprognostic (1.27e-2)" "unprognostic (3.71e-3)" "prognostic favorable (1.08e-7)" "unprognostic (8.16e-2)" "unprognostic (1.60e-1)" "unprognostic (2.64e-1)" "unprognostic (1.00e-2)" 48.1 47.8 26.7 59.7 30.8 49.9 37.8 25.8 27.0 45.0 55.0 74.4 59.0 39.2 36.0 46.6 50.8 42.3 60.9 26.0 24.2 47.7 55.7 42.0 56.5 32.6 29.3 39.1 57.9 87.3 26.8 60.3 28.8 42.7 69.1 30.6 56.2 40.8 81.7 41.9 58.4 50.9 25.3 49.0 69.3 17.4 30.3 45.5 49.0 71.4 45.6 53.4 33.0 28.7 179.7 145.4 32.0 92.8 93.7 116.6 100.3 123.2 107.8 92.9 68.0 47.5 108.2 116.1 68.9 156.2 73.7 188.8 86.5 144.3 71.1 117.0 62.8 63.8 126.1 75.3 104.6 109.0 83.5 114.3 87.2 105.7 166.3 90.9 133.7 81.0 74.4 94.9 101.3 202.8 108.2 61.4 41.2 212.7 134.3 62.1 85.6 97.4 112.3 107.2 85.8 52.5 139.5 166.4 86.0 31.4 91.0 70.6 140.6 99.6 71.6 123.8 136.4 74.2 78.6 44.8 107.9 96.6 90.9 3.1 6.6 5.2 4.9 7.5 4.1 4.4 4.3 4.8 6.1 3.5 3.0 4.4 13.1 4.3 9.3 3.9 8.3 4.1 26.7 30.8 25.8 27.0 26.0 24.2 32.6 29.3 28.8 25.3 30.3 28.7 64.0 44.8 93.9 67.9 42.7 102.2 49.6 56.6 70.6 30.0 86.5 49.0 112.3 77.2 75.2 75.4 50.1 73.8 49.2 164.3 21.5 50.1 26.1 77.5 76.2 64.9 91.8 60.2 92.1 74.7 104.9 60.5 123.8 92.3 48.8 66.1 63.1 186.6 71.0 40.4 62.5 176.8 36.7 146.4 78.6 9.8 66.8 103.4 53.4 80.6 111.0 35.7 35.0 64.3 80.9 86.4 92.0 65.5 60.8 125.8 81.0 75.7 87.8 33.7 39.5 63.5 68.6 12.3 12.4 91.1 114.2 103.4 49.3 94.4 177.2 109.0 FAM167B "C1orf90, DIORA-2, MGC10820" ENSG00000183615 "Family with sequence similarity 167 member B" Q9BTA0 1 32247222-32248856 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 44.0" "Group enriched" "Detected in many" 14 "Adipocytes: 68.5;Endothelial cells: 102.5;Hepatic stellate cells: 200.3" "Cancer enhanced" "Detected in all" "melanoma: 46.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.7" "Lineage enriched" "Detected in single" 5 "T-cells: 1.7" "Cell line enhanced" "Detected in many" "BJ hTERT+: 9.6;EFO-21: 12.0;SK-MEL-30: 30.9;U-2197: 29.9" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA029398, HPA062074" Uncertain Approved "Actin filaments" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Actin filaments" "HPA029398: AB_10602807, HPA062074: AB_2684677" "unprognostic (2.16e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (1.11e-4)" "unprognostic (6.03e-2)" "unprognostic (1.74e-2)" "unprognostic (3.36e-3)" "unprognostic (7.44e-3)" "unprognostic (3.64e-1)" "unprognostic (3.00e-3)" "unprognostic (1.02e-2)" "unprognostic (1.30e-2)" "unprognostic (8.89e-2)" "unprognostic (4.80e-2)" "unprognostic (2.69e-2)" "unprognostic (1.60e-1)" "unprognostic (8.04e-2)" "unprognostic (5.08e-2)" 19.9 19.7 4.3 4.1 3.8 0.2 10.0 3.8 6.3 14.3 4.3 7.4 2.8 12.9 0.5 4.0 10.3 4.2 11.0 3.8 4.5 44.0 10.7 20.5 2.7 4.5 4.1 4.1 8.4 4.3 14.4 4.2 4.5 16.5 2.1 1.4 4.7 5.9 3.0 2.4 8.1 5.8 4.4 1.9 7.5 0.9 5.1 0.8 19.9 1.1 1.5 13.2 7.7 4.3 0.9 1.8 0.6 0.0 1.2 1.1 0.0 4.3 9.6 1.9 2.7 0.1 0.9 0.2 12.0 7.3 2.2 1.4 0.3 0.0 0.6 0.1 0.0 0.0 4.6 0.5 0.4 0.0 0.1 1.0 0.7 1.4 0.4 2.6 3.5 0.6 0.0 0.1 0.2 0.6 0.2 0.0 0.3 0.2 4.1 0.9 0.0 1.2 1.2 0.4 1.8 0.4 2.8 0.2 30.9 0.8 0.5 0.1 3.2 0.8 0.9 29.9 0.1 0.1 0.3 0.7 0.3 0.2 0.4 0.0 0.0 0.2 0.8 0.0 0.2 0.1 0.2 0.2 0.0 0.3 0.1 0.5 0.0 0.1 0.0 0.0 1.7 0.2 4.3 3.8 3.8 6.3 3.8 4.5 4.5 4.1 4.5 4.4 5.1 4.3 68.5 0.0 1.1 0.3 3.2 0.3 0.5 0.2 0.0 0.4 2.8 2.8 0.4 0.0 0.1 5.5 0.0 0.1 2.7 1.3 0.0 0.5 0.0 1.3 3.5 102.5 0.0 8.0 0.0 0.8 0.2 3.7 1.5 1.0 0.0 0.2 200.3 1.7 0.6 0.0 0.1 1.3 0.0 8.5 2.2 0.0 2.8 1.4 1.8 2.8 0.0 0.0 2.1 0.5 0.4 0.2 1.2 1.2 0.6 0.6 0.0 0.1 1.3 0.5 0.0 0.6 1.6 0.0 0.3 0.3 1.0 0.3 2.1 0.9 0.7 0.3 FAM185A MGC35361 ENSG00000222011 "Family with sequence similarity 185 member A" Q8N0U4 7 102748971-102809225 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 64.0;Excitatory neurons: 132.4;Inhibitory neurons: 134.5;Microglial cells: 63.7;Oligodendrocyte precursor cells: 70.9;Oligodendrocytes: 89.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 6.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020470, HPA029883" Uncertain Approved Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA020470: AB_1853890, HPA029883: AB_10601903" "unprognostic (8.28e-2)" "unprognostic (2.28e-1)" "unprognostic (8.19e-2)" "unprognostic (1.20e-1)" "unprognostic (3.88e-3)" "unprognostic (6.06e-2)" "unprognostic (1.63e-2)" "unprognostic (1.59e-3)" "unprognostic (3.97e-2)" "unprognostic (4.45e-2)" "unprognostic (7.11e-2)" "unprognostic (2.03e-1)" "prognostic favorable (9.36e-5)" "unprognostic (3.64e-2)" "unprognostic (2.65e-1)" "unprognostic (2.13e-3)" "unprognostic (5.25e-2)" 0.8 1.1 0.6 0.6 0.6 0.8 0.8 1.0 0.8 1.3 0.6 1.0 0.4 0.8 0.4 1.0 0.7 0.4 1.0 0.4 0.5 1.2 2.8 0.6 0.4 0.5 0.8 1.0 1.3 1.5 0.7 0.5 0.4 1.2 0.7 1.1 0.8 0.8 3.5 1.2 0.8 0.5 0.3 0.6 1.9 0.4 0.7 0.7 0.9 2.0 0.4 1.3 1.0 1.2 0.6 2.0 0.4 2.4 0.4 0.9 1.5 0.6 1.3 0.3 0.0 1.7 2.1 0.6 0.9 0.6 1.5 2.3 1.0 0.9 0.4 1.2 0.1 0.2 0.2 2.8 0.6 0.9 1.1 0.0 1.8 0.0 0.4 1.5 0.6 0.5 1.0 1.1 1.1 3.2 2.1 0.6 0.9 2.7 0.5 0.2 0.0 6.7 0.2 1.4 0.4 1.7 4.0 4.5 0.1 0.0 2.7 0.0 1.6 0.2 1.1 2.1 0.4 3.1 1.4 0.6 0.4 0.6 0.2 0.0 1.4 1.9 1.1 1.2 1.1 2.2 0.7 1.0 1.6 0.8 0.9 0.7 3.7 0.8 0.5 1.2 0.8 0.4 0.6 0.6 1.0 0.8 0.4 0.5 0.5 0.8 0.4 0.3 0.7 1.2 2.9 3.2 1.5 64.0 5.1 4.2 8.1 5.8 9.6 8.8 5.1 3.6 6.3 11.5 6.0 0.0 10.4 13.8 5.6 2.0 19.6 4.6 5.4 5.0 3.8 4.0 1.2 9.4 132.4 2.3 6.5 4.0 9.2 4.1 0.0 7.0 6.4 7.4 4.4 5.0 134.5 3.2 6.1 2.8 1.4 3.3 7.2 3.3 7.2 63.7 3.2 4.9 2.1 70.9 89.2 2.5 1.7 5.3 6.3 3.8 4.6 11.1 3.0 21.4 13.1 4.3 4.1 9.2 5.1 6.7 4.5 8.1 4.1 7.0 3.6 7.0 FAM219A "bA573M23.5, C9orf25, FLJ39031" ENSG00000164970 "Family with sequence similarity 219 member A" Q8IW50 9 34398184-34458570 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 94.6" "Cell type enhanced" "Detected in many" "Horizontal cells: 53.8;Late spermatids: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "HDLM-2: 96.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019338, HPA052909" Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 44: HDLM-2 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA019338: AB_1845819, HPA052909: AB_2681986" "unprognostic (9.96e-3)" "unprognostic (2.16e-1)" "unprognostic (1.50e-2)" "unprognostic (1.23e-2)" "unprognostic (6.81e-2)" "unprognostic (4.07e-2)" "prognostic unfavorable (1.98e-5)" "unprognostic (2.71e-2)" "unprognostic (2.50e-1)" "unprognostic (2.95e-1)" "prognostic favorable (2.46e-4)" "unprognostic (3.46e-3)" "prognostic unfavorable (5.54e-5)" "unprognostic (2.04e-2)" "unprognostic (1.78e-1)" "unprognostic (3.34e-1)" "unprognostic (2.76e-1)" 19.8 14.0 82.5 9.0 79.4 3.8 17.5 72.4 88.0 18.5 25.9 17.0 5.4 22.5 6.2 9.8 15.7 5.6 29.9 75.9 77.5 15.7 12.7 18.8 6.5 90.0 84.8 15.3 13.2 6.4 26.3 13.4 94.6 16.3 4.6 19.3 12.1 7.0 42.7 16.2 11.9 11.9 83.8 15.1 12.7 9.7 82.9 8.3 14.9 12.6 5.0 17.7 15.7 85.4 27.9 10.6 24.5 14.0 22.3 8.5 23.8 16.5 12.4 14.0 17.7 7.4 6.3 6.1 16.6 16.1 27.7 11.4 19.6 10.6 14.0 96.0 11.2 2.5 14.6 8.0 12.5 6.1 13.6 9.0 10.5 21.0 11.7 17.4 23.4 10.6 6.1 29.6 11.0 5.6 9.5 8.5 15.8 3.8 15.6 12.1 4.1 5.3 10.1 5.9 7.8 24.8 14.3 10.3 8.5 22.2 5.2 6.1 28.0 15.4 11.9 32.3 23.2 7.8 12.0 5.1 44.2 13.9 27.8 0.6 0.1 1.1 0.3 0.1 0.2 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.5 0.2 0.2 0.1 0.4 0.1 82.5 79.4 72.4 88.0 75.9 77.5 90.0 84.8 94.6 83.8 82.9 85.4 14.3 6.4 3.3 17.3 3.3 6.2 3.7 5.6 4.0 21.1 5.1 2.9 11.7 1.5 2.5 3.7 4.2 9.4 4.3 2.1 0.0 6.1 13.8 2.0 6.0 17.4 10.8 0.4 28.6 5.1 16.8 7.8 6.1 2.8 2.5 3.4 9.3 2.8 5.9 53.8 31.8 2.3 8.2 5.5 2.6 35.1 3.7 4.1 8.8 15.0 4.5 9.3 3.1 22.1 15.9 6.6 1.7 5.7 3.0 5.1 1.3 3.0 2.3 11.0 6.6 5.2 9.1 9.9 3.8 3.0 6.5 20.7 3.5 2.9 0.9 2.7 FAM228B ENSG00000219626 "Family with sequence similarity 228 member B" P0C875 2 24076526-24169640 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 116.9;Late spermatids: 100.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052598, HPA063357" Uncertain Approved "Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Golgi apparatus" "HPA052598: AB_2681880, HPA063357: AB_2684994" "unprognostic (2.48e-1)" "unprognostic (1.98e-1)" "unprognostic (1.15e-2)" "unprognostic (2.66e-1)" "unprognostic (3.81e-1)" "unprognostic (5.05e-2)" "unprognostic (1.85e-2)" "unprognostic (9.14e-2)" "unprognostic (3.32e-1)" "unprognostic (1.32e-1)" "unprognostic (3.39e-5)" "unprognostic (5.62e-2)" "unprognostic (1.02e-2)" "unprognostic (2.07e-2)" "unprognostic (1.70e-1)" "unprognostic (5.15e-1)" "unprognostic (6.93e-2)" 21.8 15.0 44.4 2.9 48.1 7.9 17.1 53.2 63.6 21.1 33.8 20.7 1.7 12.2 19.2 6.8 18.4 9.2 26.0 40.4 47.3 17.0 4.9 11.0 5.5 45.3 43.8 21.4 8.3 14.9 30.6 6.5 45.5 21.6 4.3 8.9 7.5 12.4 13.2 8.2 10.4 7.8 45.6 12.7 11.4 33.4 45.1 6.2 14.0 9.7 5.0 16.9 14.5 54.9 2.6 1.9 3.7 13.9 9.6 12.5 0.4 6.3 5.9 2.3 1.5 0.2 1.6 3.3 3.1 4.8 4.6 0.2 0.9 0.7 2.2 5.0 6.1 4.0 0.6 0.7 18.6 2.0 1.0 11.7 6.5 1.0 9.3 15.5 5.0 3.0 0.4 4.0 3.1 4.1 0.6 9.4 1.2 0.3 5.4 3.2 1.7 1.5 6.8 2.7 1.3 10.0 2.0 0.0 11.3 5.9 3.8 9.3 5.2 4.2 0.4 0.8 2.1 6.7 2.2 3.9 9.2 7.1 2.9 9.4 5.0 10.1 5.2 3.5 2.6 7.4 3.7 4.2 6.0 4.8 5.5 5.7 4.1 4.5 3.3 9.9 3.8 3.1 44.4 48.1 53.2 63.6 40.4 47.3 45.3 43.8 45.5 45.6 45.1 54.9 19.1 51.3 35.3 49.9 10.7 6.4 9.5 8.8 5.2 24.7 11.5 18.7 24.7 10.0 34.9 14.7 8.4 9.7 17.2 1.6 31.3 5.4 116.9 13.2 11.8 17.4 9.6 6.9 52.1 5.5 4.2 20.1 2.6 5.5 25.9 22.3 20.7 3.5 10.4 37.0 52.1 3.2 10.2 12.8 21.7 100.5 42.3 13.2 10.6 39.4 14.7 39.0 21.6 41.7 78.3 3.8 1.1 38.4 4.6 4.3 2.4 12.3 41.9 27.7 52.6 24.3 21.6 39.4 11.4 2.6 7.4 3.3 13.2 17.4 3.1 5.4 FAM3B "2-21, C21orf11, C21orf76, D21M16SJHU19e, ORF9, PANDER, PRED44" ENSG00000183844 "FAM3 metabolism regulating signaling molecule B" P58499 21 41304212-41357727 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 142.6;pancreas: 212.3;salivary gland: 119.4;stomach 1: 114.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 304.6;Exocrine glandular cells: 399.9;Proximal enterocytes: 831.6" "Cancer enhanced" "Detected in many" "prostate cancer: 40.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 1.4;neutrophil: 2.8" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.8" "Cell line enhanced" "Detected in some" "CACO-2: 19.5;CAPAN-2: 11.7;Hep G2: 32.1;OE19: 27.3;RPMI-8226: 80.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015885, HPA029777, CAB034131" Enhanced Approved Vesicles "Secreted to blood" NA NA 2080000 250000 "Cluster 1: Neutrophils - Mixed function" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB034131: AB_2231472, HPA015885: AB_1848396, HPA029777: AB_2673194" "unprognostic (2.88e-1)" "unprognostic (3.31e-3)" "unprognostic (5.13e-2)" "unprognostic (1.27e-1)" "unprognostic (2.62e-1)" "unprognostic (6.32e-3)" "unprognostic (1.41e-1)" "unprognostic (8.79e-3)" "unprognostic (9.38e-2)" "unprognostic (1.70e-1)" "unprognostic (4.65e-1)" "unprognostic (3.78e-1)" "unprognostic (5.60e-3)" "unprognostic (1.57e-1)" "unprognostic (1.80e-1)" "unprognostic (1.78e-1)" "unprognostic (1.55e-3)" 1.5 0.1 0.0 2.5 0.1 0.8 17.7 0.1 0.3 4.9 1.3 5.9 142.6 0.3 22.1 56.2 17.2 16.2 0.6 0.1 0.1 17.9 2.6 9.3 1.5 0.1 0.1 0.2 212.3 0.5 5.4 15.2 0.1 37.9 0.1 0.0 119.4 8.7 0.1 2.3 135.0 0.5 0.1 0.6 114.9 6.9 0.1 3.1 8.0 0.0 16.8 34.4 16.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 19.5 11.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 32.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.4 0.9 27.3 0.0 0.2 0.0 80.6 0.0 5.8 0.4 0.4 0.0 0.7 0.4 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.3 1.4 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 2.8 0.0 0.3 0.7 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.0 22.4 25.7 0.0 0.8 1.3 17.0 2.9 1.2 0.0 101.3 123.1 0.2 102.9 36.5 66.2 0.0 304.6 1.4 2.7 25.4 172.1 25.2 0.2 0.1 2.5 0.0 0.0 0.1 399.9 11.1 3.4 147.3 0.7 1.3 0.6 0.4 0.3 27.0 0.0 0.1 120.9 42.7 5.0 15.8 11.5 0.6 3.9 5.4 1.9 2.1 0.0 0.0 0.0 0.1 144.6 169.0 0.4 0.2 64.9 831.6 0.7 22.4 0.0 0.0 0.4 1.8 28.0 8.1 29.1 1.3 161.3 0.9 0.0 125.2 130.5 FAM47E "FLJ42946, LOC100129583" ENSG00000189157 "Family with sequence similarity 47 member E" Q6ZV65 4 76214040-76283783 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 47.3;Endometrial ciliated cells: 34.0;Respiratory ciliated cells: 91.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.3" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in many" 5 "OE19: 28.0" HPA053331 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 21: OE19 - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA053331: AB_2682115" "unprognostic (1.59e-1)" "unprognostic (1.76e-2)" "unprognostic (3.68e-2)" "unprognostic (3.90e-4)" "unprognostic (1.37e-2)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (5.63e-2)" "unprognostic (1.06e-1)" "unprognostic (2.21e-2)" "unprognostic (3.73e-2)" "unprognostic (1.31e-1)" "unprognostic (2.16e-8)" "unprognostic (1.01e-1)" "unprognostic (1.84e-2)" "unprognostic (3.04e-2)" "unprognostic (3.01e-2)" 6.2 4.9 7.6 0.4 8.3 1.0 6.8 7.5 8.8 2.9 7.9 2.6 3.2 1.7 11.0 1.3 19.6 4.0 1.9 8.0 8.4 7.3 9.1 4.0 0.5 8.1 8.5 0.8 9.1 7.6 8.5 1.5 7.8 4.2 2.9 8.8 4.4 2.7 6.4 1.3 3.5 1.1 7.8 1.2 5.1 8.0 9.5 0.7 9.7 3.2 0.4 1.9 0.7 9.1 0.6 2.1 2.1 0.6 1.6 0.2 0.5 0.2 2.0 0.4 0.4 2.6 2.2 0.1 0.6 0.7 4.5 0.6 0.9 0.5 0.7 2.1 0.1 0.1 1.3 3.6 0.9 0.5 0.3 1.0 0.5 0.6 0.5 0.9 0.2 0.3 0.2 1.5 0.6 3.1 0.2 0.2 0.4 28.0 1.0 0.3 0.5 0.3 3.4 1.8 3.7 2.9 1.0 1.6 0.3 0.5 1.7 0.2 0.5 0.4 0.5 1.2 0.5 5.5 1.2 0.1 1.6 0.2 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.1 0.6 0.0 0.0 7.6 8.3 7.5 8.8 8.0 8.4 8.1 8.5 7.8 7.8 9.5 9.1 1.6 9.6 2.6 4.2 0.4 0.6 2.5 5.1 0.0 12.9 7.7 9.1 7.9 8.6 8.4 0.0 12.5 3.3 0.1 6.2 9.8 7.5 47.3 34.0 0.6 1.8 7.7 0.8 1.0 7.8 1.6 1.5 3.1 2.0 0.0 1.5 1.8 3.6 0.8 1.7 1.1 5.7 14.2 1.0 0.0 6.2 0.6 0.7 1.8 1.0 0.0 4.7 0.0 0.0 2.9 5.8 3.0 0.4 0.4 2.8 13.0 10.3 91.4 7.4 0.0 2.0 2.2 8.8 4.3 0.3 0.3 3.4 0.2 0.8 3.1 1.9 FAM78A "C9orf59, FLJ00024" ENSG00000126882 "Family with sequence similarity 78 member A" Q5JUQ0 9 131258076-131276510 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 53.7;testis: 31.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 55.7;Early spermatids: 90.6;Granulosa cells: 167.2;Late spermatids: 120.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 39.3;HEL: 38.6;HL-60: 38.7;NB-4: 60.7;THP-1: 53.5;U-937: 35.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021472, HPA023914" Uncertain Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 23: Testis - Cell cycle regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Vesicles" "HPA021472: AB_1848411, HPA023914: AB_1848412" "unprognostic (5.16e-2)" "prognostic favorable (3.67e-4)" "unprognostic (3.65e-2)" "unprognostic (2.07e-2)" "unprognostic (2.71e-1)" "prognostic favorable (2.00e-4)" "unprognostic (3.24e-1)" "unprognostic (5.49e-2)" "unprognostic (1.46e-2)" "unprognostic (5.83e-1)" "unprognostic (5.84e-2)" "unprognostic (6.79e-2)" "unprognostic (1.59e-3)" "unprognostic (2.61e-3)" "unprognostic (7.42e-2)" "unprognostic (2.61e-2)" "unprognostic (2.39e-1)" 2.9 2.0 3.8 13.8 5.6 21.7 1.7 3.6 6.3 1.4 1.8 2.4 2.7 1.5 0.3 1.7 1.3 3.1 26.5 5.1 3.7 1.6 1.5 6.1 24.5 5.6 4.1 1.4 1.1 1.1 1.2 5.3 4.9 1.4 1.6 4.6 2.7 0.9 53.7 1.2 8.9 1.8 4.6 21.6 3.8 31.9 5.8 21.1 1.6 20.2 14.9 3.5 1.1 5.7 0.7 0.3 2.5 5.6 1.7 0.5 39.3 0.3 0.3 0.5 0.2 0.3 0.2 17.1 0.2 0.3 0.8 0.1 16.0 0.2 0.1 4.4 1.4 38.6 0.6 0.3 0.6 38.7 1.5 0.4 0.8 0.0 0.1 0.5 22.2 10.8 13.8 4.7 0.5 6.0 1.7 60.7 2.6 0.3 0.6 4.0 2.3 23.7 0.2 0.1 1.5 2.1 2.3 0.8 2.4 0.9 1.4 53.5 0.6 2.3 2.4 1.3 0.1 3.4 1.9 9.7 0.3 35.9 0.6 0.5 9.7 17.6 9.2 12.6 7.4 14.2 8.9 10.1 6.0 15.9 11.0 9.3 9.8 3.1 9.9 2.7 9.5 8.7 3.8 5.6 3.6 6.3 5.1 3.7 5.6 4.1 4.9 4.6 5.8 5.7 3.2 0.0 1.5 0.0 15.5 0.9 0.0 0.0 0.0 55.7 0.4 0.5 17.6 0.0 0.0 1.8 0.0 1.1 19.0 0.0 0.0 0.1 90.6 0.1 0.2 6.8 0.0 3.4 5.0 0.0 37.6 3.1 0.5 0.1 1.3 167.2 6.4 0.5 25.7 0.0 1.7 0.0 0.0 21.7 10.6 120.3 5.0 14.8 1.8 15.9 15.6 0.8 30.9 1.0 0.1 0.1 0.0 3.4 12.0 0.0 0.0 0.2 0.0 1.8 0.0 0.6 6.3 2.2 1.2 0.0 0.9 1.4 17.4 1.0 0.0 0.1 FAM8A1 AHCP ENSG00000137414 "Family with sequence similarity 8 member A1" Q9UBU6 6 17600302-17611715 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Early spermatids: 759.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044698, HPA073675" Approved Approved "Golgi apparatus" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus" "HPA044698: AB_2679051, HPA073675: AB_2732236" "unprognostic (4.06e-1)" "unprognostic (2.32e-1)" "unprognostic (9.11e-2)" "unprognostic (6.90e-2)" "unprognostic (1.99e-2)" "unprognostic (5.17e-3)" "unprognostic (6.13e-2)" "unprognostic (1.93e-2)" "unprognostic (2.04e-2)" "unprognostic (1.09e-3)" "unprognostic (4.44e-2)" "unprognostic (3.50e-1)" "unprognostic (1.56e-2)" "unprognostic (3.85e-2)" "unprognostic (3.71e-1)" "unprognostic (7.59e-2)" "unprognostic (2.98e-1)" 18.6 16.1 16.3 10.7 17.3 31.6 19.1 19.0 19.5 20.4 16.6 19.9 16.9 27.3 18.9 13.9 20.6 21.1 14.8 17.4 20.3 24.0 77.9 18.9 10.4 18.2 17.2 27.8 15.0 22.3 13.0 14.9 18.2 20.9 22.8 27.1 23.0 22.3 18.9 14.0 16.7 24.8 20.2 14.3 12.7 17.2 21.1 17.1 23.2 21.7 8.2 14.5 12.6 20.6 9.5 3.7 13.5 32.3 45.6 42.6 11.1 15.0 20.4 7.6 13.1 21.4 3.1 8.1 35.2 25.6 8.3 7.6 20.5 13.0 9.9 6.9 29.1 9.8 12.5 46.2 20.1 6.2 9.6 22.6 20.7 8.7 6.0 24.2 17.0 8.9 20.2 16.2 12.0 11.7 4.6 19.2 5.6 11.6 5.6 12.1 13.0 25.0 25.6 7.5 4.1 21.4 11.7 25.0 23.7 23.1 29.0 9.5 13.3 9.7 3.4 14.9 5.5 13.4 12.0 8.0 8.8 7.1 13.4 2.6 0.3 1.0 1.1 0.4 1.2 0.0 0.5 1.0 0.2 0.1 0.7 1.1 5.5 1.5 0.2 0.2 0.4 0.3 16.3 17.3 19.0 19.5 17.4 20.3 18.2 17.2 18.2 20.2 21.1 20.6 16.8 19.2 27.1 8.8 7.0 13.4 9.7 6.6 14.2 27.6 15.1 13.5 15.3 21.5 12.1 29.5 14.6 10.0 15.7 63.4 5.9 9.2 759.2 26.4 24.0 14.1 12.0 4.2 17.1 7.9 12.0 23.0 10.7 20.6 1.3 8.6 25.4 77.5 6.2 15.2 17.9 10.8 8.2 24.4 6.4 187.8 36.7 8.6 5.4 3.7 8.7 19.3 14.4 8.0 13.8 7.5 25.7 30.9 12.8 7.5 30.4 12.4 20.5 16.7 32.9 20.3 18.7 46.6 18.0 14.3 15.9 12.2 14.0 9.7 16.7 7.8 FASLG "APT1LG1, CD178, FasL, TNFSF6" ENSG00000117560 "Fas ligand" P48023 1 172659103-172666876 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Apoptosis, Transcription, Transcription regulation" "Cytokine, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.7" "Group enriched" "Detected in some" 14 "dendritic cells: 43.4;NK-cells: 79.3;T-cells: 28.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 58.1" "Group enriched" "Detected in many" 9 "NK-cells: 41.5;T-cells: 58.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054959 Approved "Secreted to blood" NA NA 73600 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA054959: AB_2682650" "unprognostic (1.09e-3)" "unprognostic (1.41e-2)" "unprognostic (8.69e-2)" "unprognostic (1.54e-7)" "unprognostic (3.29e-1)" "unprognostic (2.23e-3)" "unprognostic (5.44e-2)" "unprognostic (1.84e-2)" "unprognostic (4.67e-2)" "unprognostic (4.76e-2)" "unprognostic (8.88e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (1.59e-6)" "unprognostic (3.49e-2)" "unprognostic (1.22e-1)" "unprognostic (1.15e-2)" "unprognostic (3.82e-3)" 0.3 0.8 0.1 1.0 0.2 2.8 0.6 0.1 0.2 0.4 0.1 0.8 1.9 0.5 0.7 0.3 0.3 1.1 0.3 0.2 0.1 0.3 1.1 2.0 5.7 0.3 0.2 0.3 0.1 0.0 0.1 0.2 0.2 0.5 0.9 0.0 0.9 0.3 0.1 0.4 1.4 0.3 0.0 4.1 1.5 0.2 0.1 0.6 0.2 0.0 1.8 0.8 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.5 0.1 0.0 58.1 0.2 35.5 0.0 11.5 31.4 0.1 0.0 2.2 25.0 1.9 41.5 0.1 0.0 0.2 14.9 0.1 0.2 0.1 0.2 0.2 0.1 0.3 0.2 0.2 0.0 0.1 0.4 0.4 0.0 2.5 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 43.4 0.1 0.0 0.1 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.3 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.3 1.2 0.0 0.0 0.6 1.8 0.0 0.9 0.0 79.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 28.8 0.0 0.0 0.1 FBLN1 FBLN ENSG00000077942 "Fibulin 1" P23142 22 45502238-45601135 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 666.3;Endometrial stromal cells: 628.2;Extravillous trophoblasts: 651.6;Fibroblasts: 1506.5;Syncytiotrophoblasts: 1215.9" "Cancer enhanced" "Detected in all" "endometrial cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 1839.4;ASC TERT1: 809.8;BJ: 1029.3;BJ hTERT+: 1615.9;HSkMC: 1345.8;RT4: 1485.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001612, HPA001613, CAB004393, CAB068187" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 21000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB004393: AB_671972, CAB068187: AB_2665634, HPA001612: AB_1078825, HPA001613: AB_1078824" "unprognostic (6.62e-2)" "unprognostic (2.47e-2)" "unprognostic (1.64e-1)" "prognostic favorable (9.28e-4)" "unprognostic (1.26e-3)" "unprognostic (4.82e-2)" "unprognostic (9.79e-3)" "unprognostic (2.49e-1)" "unprognostic (6.30e-2)" "unprognostic (3.86e-2)" "unprognostic (2.84e-2)" "unprognostic (3.30e-2)" "prognostic unfavorable (3.02e-10)" "unprognostic (1.08e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-2)" "unprognostic (3.64e-2)" 359.3 123.1 17.3 72.3 29.5 1.7 318.2 27.8 27.5 1131.0 802.4 200.7 75.5 410.6 126.0 305.8 497.6 676.1 773.7 47.0 11.9 61.3 15.7 414.9 16.1 21.8 24.5 214.1 106.3 216.9 90.3 505.7 23.1 466.8 83.6 3.1 121.2 158.5 36.0 296.3 174.5 180.3 15.9 24.9 269.1 21.9 24.7 20.5 195.3 47.5 13.0 704.6 940.5 14.6 17.7 41.6 122.9 258.0 1839.4 809.8 559.8 1029.3 1615.9 89.8 33.8 179.2 5.2 0.4 42.8 38.6 2.5 90.9 78.0 2.7 10.8 0.9 21.0 0.4 209.4 121.5 243.2 1.0 1.0 1345.8 15.8 89.6 32.7 1.8 0.2 1.4 0.9 2.1 63.3 2.4 0.8 3.2 173.8 3.7 15.4 1.4 0.9 2.1 41.1 1485.2 8.7 162.7 127.5 589.6 0.6 344.3 3.7 5.4 8.0 17.4 109.3 465.8 1.0 1.6 0.8 1.4 1.2 1.0 43.5 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.5 0.1 0.1 0.1 0.2 0.0 2.4 1.2 0.0 0.1 17.3 29.5 27.8 27.5 47.0 11.9 21.8 24.5 23.1 15.9 24.7 14.6 34.4 6.4 1.3 34.3 1.2 170.9 113.4 54.8 21.1 0.1 5.3 11.6 20.1 10.0 28.3 1.8 0.0 666.3 1.6 0.1 0.0 1.3 10.5 61.5 628.2 34.5 0.0 0.0 0.5 0.2 651.6 1506.5 38.7 256.5 1.3 29.0 22.1 0.6 82.4 0.0 0.8 0.3 6.1 0.0 222.9 25.4 92.2 11.4 170.7 41.2 0.0 0.1 0.0 0.0 0.4 1.0 0.1 30.5 4.5 47.4 0.0 0.3 10.2 0.6 118.3 37.1 81.5 42.2 68.7 23.8 130.3 1215.9 18.2 2.3 0.4 86.9 FBN1 "FBN, MASS, MFS1, OCTD, SGS, WMS" ENSG00000166147 "Fibrillin 1" P35555 15 48408313-48645721 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Heparin-binding, Hormone" "Aortic aneurysm, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 60.9;placenta: 76.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 132.4;Fibroblasts: 388.5;Leydig cells: 236.1;Oligodendrocytes: 218.7;Peritubular cells: 227.2;Skeletal myocytes: 139.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 215.1;ASC TERT1: 460.7;fHDF/TERT166: 420.8;HSkMC: 251.3;hTERT-RPE1: 211.1;U-138 MG: 206.9;U-2197: 305.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002670, HPA017759, HPA021057, CAB058696, CAB068188" Enhanced Approved Cytosol "Secreted to blood" NA NA 520000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "CAB002670: , CAB058696: AB_2665596, CAB068188: AB_2665597, HPA017759: AB_1848584, HPA021057: AB_1848586" "unprognostic (3.97e-2)" "unprognostic (1.55e-2)" "unprognostic (2.40e-2)" "unprognostic (9.50e-2)" "unprognostic (1.51e-1)" "unprognostic (9.49e-2)" "unprognostic (2.00e-2)" "unprognostic (4.79e-2)" "unprognostic (7.82e-2)" "unprognostic (1.50e-2)" "unprognostic (2.78e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (7.44e-5)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.25e-2)" "unprognostic (8.69e-3)" "prognostic unfavorable (5.11e-4)" 60.9 4.4 1.4 14.5 5.4 3.4 13.7 2.8 2.8 36.0 9.5 8.3 3.8 15.2 6.3 12.6 12.2 27.3 23.5 0.8 2.0 2.7 2.9 10.0 3.7 5.2 6.0 28.4 3.3 3.0 2.5 76.7 3.7 8.0 11.7 1.3 4.6 13.2 4.5 5.7 6.6 35.7 2.3 6.4 6.0 7.1 4.7 2.9 18.6 21.2 3.5 18.8 9.9 5.0 0.1 5.2 19.8 22.4 215.1 460.7 0.2 175.8 62.9 51.1 32.4 0.1 0.3 0.1 7.9 420.8 0.4 0.7 3.9 0.6 45.9 20.7 1.2 2.0 88.5 0.2 120.7 0.8 0.3 251.3 0.1 135.9 15.6 211.1 55.5 1.6 0.0 0.4 55.6 0.0 1.5 0.2 4.0 0.2 7.1 0.1 17.0 0.2 5.9 0.5 0.2 12.9 0.0 2.2 0.1 15.3 0.2 1.4 106.8 206.9 6.2 305.8 37.6 1.2 1.0 0.0 138.9 0.3 13.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.4 5.4 2.8 2.8 0.8 2.0 5.2 6.0 3.7 2.3 4.7 5.0 50.0 0.0 1.3 34.9 0.4 25.6 0.8 1.5 0.6 6.1 1.3 3.4 14.2 0.0 5.8 12.9 0.0 132.4 0.4 0.0 0.0 0.2 8.7 4.2 105.2 36.1 0.0 5.5 82.3 0.6 40.8 388.5 3.1 2.0 1.3 22.5 34.6 0.6 15.3 0.0 123.5 0.0 0.0 0.8 39.0 22.8 236.1 5.7 42.7 30.0 2.3 0.8 0.0 76.9 218.7 1.7 0.0 227.2 1.7 0.7 0.1 0.6 3.3 0.2 26.3 139.5 55.8 3.3 3.4 0.8 20.6 65.8 4.3 51.3 0.0 0.2 FBRS "FBS, FBS1, FLJ11618" ENSG00000156860 Fibrosin Q9HAH7 16 30658431-30670810 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 109.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044117 Approved Approved Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 6: T47d - Mammary gland" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA044117: AB_10794394" "unprognostic (1.87e-1)" "unprognostic (8.48e-3)" "unprognostic (2.41e-2)" "unprognostic (9.52e-3)" "unprognostic (1.03e-1)" "unprognostic (4.80e-2)" "unprognostic (2.07e-3)" "unprognostic (7.01e-3)" "unprognostic (6.32e-2)" "unprognostic (7.65e-2)" "unprognostic (4.57e-3)" "unprognostic (1.01e-1)" "unprognostic (1.25e-2)" "unprognostic (2.13e-1)" "unprognostic (4.16e-1)" "unprognostic (1.42e-1)" "unprognostic (1.63e-1)" 25.6 34.3 23.0 24.4 22.2 55.9 25.8 21.5 24.6 34.2 14.9 39.1 21.2 35.6 5.5 57.2 36.0 9.4 28.7 22.9 19.7 33.3 29.9 29.2 21.8 24.7 20.9 33.8 29.8 16.6 57.6 12.6 19.4 37.3 6.5 6.5 30.2 15.6 38.4 53.5 40.0 9.7 16.8 53.4 33.8 117.3 22.9 21.3 36.6 11.4 15.9 34.7 33.2 23.0 28.8 30.2 15.6 12.9 15.3 15.5 39.5 20.9 16.9 17.7 13.3 17.8 25.9 26.8 34.0 17.0 16.0 23.6 16.6 19.9 8.3 72.7 41.5 36.0 29.3 33.0 37.4 26.5 52.3 23.1 26.4 34.3 16.6 19.8 22.0 24.4 32.0 50.2 13.1 59.1 33.7 51.7 4.4 12.9 19.0 48.5 11.8 29.4 18.8 21.2 21.8 24.5 16.4 31.2 22.9 6.7 70.5 34.6 34.3 40.0 24.2 25.0 27.8 58.6 30.5 25.4 38.4 25.6 24.1 0.0 1.0 0.8 0.8 0.4 0.8 0.6 0.7 0.8 0.5 0.7 0.2 0.9 2.1 0.5 0.6 1.0 0.0 0.9 23.0 22.2 21.5 24.6 22.9 19.7 24.7 20.9 19.4 16.8 22.9 23.0 21.2 16.0 21.8 9.8 30.0 18.7 15.9 13.2 38.7 22.3 26.8 19.3 9.3 11.5 11.0 7.3 33.3 10.2 38.1 36.3 5.9 11.0 82.2 33.4 25.1 18.2 16.8 4.6 9.5 14.7 9.3 15.8 29.0 32.2 19.0 21.5 19.2 9.4 14.0 43.7 8.7 21.5 10.2 15.8 22.0 109.9 17.1 25.8 10.6 7.5 20.1 14.7 15.5 7.5 14.5 21.1 26.3 16.1 13.3 22.2 33.5 8.9 24.4 25.7 0.0 19.0 17.7 69.1 23.9 37.8 24.3 33.0 28.8 22.2 19.3 27.9 FBXL17 "DKFZP434C1715, Fbl17, Fbx13, FBXO13" ENSG00000145743 "F-box and leucine rich repeat protein 17" Q9UF56 5 107859035-108382098 "Predicted intracellular proteins, Predicted membrane proteins" "Neurogenesis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Astrocytes: 270.0;Excitatory neurons: 568.2;Inhibitory neurons: 578.0;Microglial cells: 205.2;Oligodendrocyte precursor cells: 302.6;Oligodendrocytes: 256.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036410, HPA036411" Uncertain Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA036410: AB_2675109, HPA036411: AB_10669603" "unprognostic (8.15e-2)" "unprognostic (3.77e-2)" "unprognostic (2.18e-2)" "unprognostic (1.21e-1)" "unprognostic (4.58e-2)" "unprognostic (2.72e-2)" "unprognostic (2.08e-2)" "unprognostic (2.65e-1)" "unprognostic (6.67e-2)" "unprognostic (3.08e-2)" "unprognostic (5.98e-2)" "unprognostic (6.30e-2)" "prognostic favorable (4.60e-8)" "unprognostic (1.86e-1)" "unprognostic (3.34e-1)" "prognostic unfavorable (3.27e-4)" "unprognostic (3.35e-2)" 15.4 13.8 11.8 7.8 13.1 5.9 10.4 7.5 15.3 10.8 3.8 10.1 10.6 9.9 8.9 12.0 9.0 9.1 27.0 12.4 12.5 16.9 14.2 8.9 8.5 9.0 12.2 9.3 10.0 26.0 5.7 5.9 9.0 11.8 10.4 25.6 9.8 13.7 55.8 8.7 10.9 11.7 10.5 10.7 10.1 8.6 11.8 10.1 24.6 41.7 10.7 8.5 4.5 10.3 8.7 8.5 9.6 17.7 15.8 16.4 6.4 10.4 23.3 8.4 11.3 1.7 17.9 9.7 16.0 16.9 13.0 3.8 7.7 11.9 13.0 9.8 6.9 9.2 9.0 4.2 8.2 6.2 10.1 11.8 17.4 7.8 5.7 16.3 10.1 3.9 1.3 12.2 18.5 6.5 5.4 7.9 1.3 6.7 7.9 7.6 12.8 12.7 11.7 11.9 8.2 14.0 13.6 11.9 13.4 6.6 9.4 14.6 11.0 18.9 5.9 5.9 13.6 9.5 14.3 7.0 16.7 9.4 12.6 0.1 0.1 0.8 0.4 0.2 0.4 0.2 0.4 0.4 0.2 0.3 0.4 0.3 0.3 0.2 0.1 0.4 0.2 0.1 11.8 13.1 7.5 15.3 12.4 12.5 9.0 12.2 9.0 10.5 11.8 10.3 13.2 19.2 14.5 270.0 13.9 16.8 7.4 7.5 6.8 37.2 18.6 10.2 38.3 17.2 8.3 29.5 56.3 4.8 12.8 22.8 17.6 7.3 5.6 8.5 9.7 12.3 29.9 5.7 568.2 13.1 6.5 12.1 12.2 10.7 16.5 12.2 21.0 21.4 8.4 30.3 578.0 21.7 2.0 21.0 14.1 5.4 14.0 9.9 16.0 205.2 13.1 20.8 12.3 302.6 256.1 13.3 16.0 16.6 10.7 8.6 14.4 15.0 6.1 50.4 0.0 16.6 9.8 9.5 3.9 10.6 24.6 4.5 12.6 13.8 16.6 8.8 FBXL19 "CXXC11, DKFZp434K0410, Fbl19, JHDM1C" ENSG00000099364 "F-box and leucine rich repeat protein 19" Q6PCT2 16 30923055-30948783 "Predicted intracellular proteins" "Ubl conjugation pathway" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074250 Approved Nucleoplasm NA No "Cluster 15: NK-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA074250: " "unprognostic (1.37e-1)" "prognostic unfavorable (3.27e-4)" "unprognostic (1.03e-1)" "unprognostic (3.80e-2)" "unprognostic (1.40e-1)" "unprognostic (2.20e-1)" "prognostic unfavorable (3.54e-4)" "unprognostic (3.61e-2)" "unprognostic (2.52e-1)" "unprognostic (2.89e-1)" "unprognostic (1.48e-1)" "unprognostic (6.95e-3)" "unprognostic (1.37e-3)" "unprognostic (6.02e-2)" "unprognostic (1.60e-1)" "unprognostic (2.45e-2)" "unprognostic (2.38e-2)" 5.4 7.7 16.5 9.8 14.8 8.3 5.5 4.4 27.9 8.7 1.9 8.6 10.4 8.5 4.0 16.5 7.3 8.5 5.6 16.8 10.1 11.5 4.3 5.8 9.7 9.4 8.6 8.4 6.7 7.2 11.4 10.1 9.1 9.9 3.8 8.5 8.9 5.4 4.8 12.7 8.8 4.6 3.1 9.9 8.7 30.0 12.4 10.0 7.9 4.0 5.1 8.5 9.6 14.4 17.5 46.0 44.7 35.6 8.0 8.1 38.6 24.2 12.3 18.3 17.2 24.8 23.9 27.1 27.4 14.4 14.2 24.3 35.9 25.8 14.0 76.3 110.0 30.0 84.0 36.5 9.9 33.5 69.9 8.3 20.4 22.6 16.0 15.9 30.0 37.7 80.0 26.3 10.3 46.9 36.4 46.2 44.4 13.0 15.5 73.1 14.2 27.0 17.7 23.6 29.6 56.3 8.5 53.0 13.7 25.1 32.5 34.8 30.0 20.2 26.1 13.5 17.1 23.1 20.4 16.9 24.7 49.0 29.9 0.0 0.4 0.5 0.3 0.2 0.3 0.5 0.1 0.1 0.2 0.2 0.0 0.3 0.5 0.9 0.0 0.7 0.2 0.1 16.5 14.8 4.4 27.9 16.8 10.1 9.4 8.6 9.1 3.1 12.4 14.4 3.4 0.0 1.1 4.9 1.5 8.3 2.4 2.5 2.8 6.1 6.8 4.1 1.5 4.3 2.9 3.7 12.5 5.7 4.0 8.9 0.0 6.1 5.6 3.8 4.7 5.0 2.4 1.3 4.5 7.1 5.4 3.1 3.6 6.0 0.0 8.9 3.6 2.3 5.2 1.7 5.0 6.5 2.0 2.8 3.9 6.5 1.5 3.4 0.0 3.7 3.3 2.8 4.1 3.0 2.1 8.6 4.1 2.6 1.7 6.4 3.3 5.1 1.8 6.0 6.6 2.2 3.5 4.7 2.9 5.4 8.9 9.3 2.0 4.9 8.5 6.5 FBXL2 "FBL2, FBL3" ENSG00000153558 "F-box and leucine rich repeat protein 2" Q9UKC9 3 33277025-33403662 "Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 48.8;Excitatory neurons: 125.0;Inhibitory neurons: 92.8;Late spermatids: 50.7;Oligodendrocyte precursor cells: 55.8;Oligodendrocytes: 49.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 5.7;LHCN-M2: 6.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003240, HPA061783" Approved Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA003240: , HPA061783: AB_2684605" "unprognostic (5.73e-2)" "unprognostic (4.47e-2)" "unprognostic (7.92e-2)" "unprognostic (7.21e-2)" "unprognostic (3.68e-1)" "unprognostic (1.59e-1)" "unprognostic (1.10e-2)" "unprognostic (2.09e-1)" "unprognostic (3.16e-1)" "unprognostic (2.00e-1)" "unprognostic (4.31e-2)" "unprognostic (1.06e-1)" "prognostic favorable (3.35e-4)" "unprognostic (3.30e-3)" "unprognostic (9.72e-2)" "unprognostic (4.28e-2)" "unprognostic (5.90e-2)" 0.9 1.3 3.6 0.4 3.8 0.3 1.0 2.2 4.0 1.1 4.2 1.1 0.7 1.0 2.1 0.4 1.5 0.6 0.9 3.5 3.7 1.4 0.2 1.2 0.3 2.9 2.6 1.4 1.1 2.7 2.7 1.4 3.0 1.0 0.2 4.2 0.8 1.6 0.2 0.6 0.5 0.8 1.6 0.5 0.8 1.1 3.3 0.2 2.3 0.0 0.2 0.8 0.9 2.7 2.7 0.7 1.0 1.0 1.5 2.4 0.4 2.0 1.6 1.8 2.6 0.5 3.1 0.1 0.6 1.3 0.8 0.5 0.9 2.1 1.2 0.2 1.1 0.4 2.3 0.5 1.8 0.2 0.4 0.9 1.6 1.1 0.8 5.7 3.3 1.9 0.5 0.2 6.2 0.2 0.5 0.3 0.7 0.3 0.6 0.1 0.6 0.1 4.6 0.7 1.1 1.1 0.9 0.5 0.8 1.7 1.3 0.7 2.5 0.8 0.7 0.6 1.1 0.2 0.1 0.1 0.8 0.2 0.6 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.0 3.6 3.8 2.2 4.0 3.5 3.7 2.9 2.6 3.0 1.6 3.3 2.7 2.7 3.2 7.3 22.2 1.0 1.1 7.6 5.6 1.8 15.3 3.0 3.7 2.4 2.8 4.8 5.5 25.0 0.5 0.4 0.1 3.9 3.9 48.8 18.8 3.6 3.8 0.0 0.0 125.0 0.4 1.5 5.0 5.6 6.2 0.0 6.2 2.2 0.1 0.5 18.5 92.8 0.3 8.2 0.8 2.4 50.7 1.5 0.5 1.8 22.5 0.1 6.6 0.0 55.8 49.6 4.2 0.1 4.1 0.3 4.2 0.2 3.2 16.5 17.7 6.6 3.6 3.9 21.3 8.6 0.7 1.1 0.7 1.5 3.5 0.1 3.8 FBXL3 "FBL3, FBL3A, FBXL3A" ENSG00000005812 "F-box and leucine rich repeat protein 3" Q9UKT7 13 76992598-77027195 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Biological rhythms, Ubl conjugation pathway" "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053283, HPA065626" Enhanced "Nuclear bodies" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 6: Erythroid cells - Oxygen transport" "Nuclear bodies" "HPA053283: AB_2682100, HPA065626: AB_2685523" "unprognostic (3.98e-1)" "unprognostic (3.00e-2)" "unprognostic (1.55e-2)" "unprognostic (7.24e-2)" "unprognostic (9.92e-2)" "unprognostic (1.01e-1)" "unprognostic (2.75e-1)" "unprognostic (2.23e-1)" "unprognostic (5.12e-2)" "unprognostic (8.70e-2)" "unprognostic (2.81e-1)" "unprognostic (4.24e-2)" "unprognostic (1.10e-3)" "unprognostic (8.52e-2)" "unprognostic (1.43e-1)" "unprognostic (1.97e-1)" "unprognostic (2.78e-1)" 45.7 25.0 17.9 24.0 20.4 69.1 42.6 23.5 26.1 31.7 12.4 27.4 24.0 31.4 23.1 27.9 27.4 24.2 25.1 17.1 17.5 37.8 31.4 29.8 32.7 17.6 17.4 44.6 20.8 29.7 9.7 32.5 18.3 29.9 25.1 21.1 22.9 26.2 30.0 30.5 25.0 27.8 18.5 31.3 22.2 30.0 17.0 36.2 48.0 37.9 31.4 25.4 23.1 28.1 43.4 11.1 21.4 14.8 50.7 50.1 17.0 48.6 39.6 28.3 36.0 16.0 30.1 27.9 31.6 43.1 17.1 31.9 21.4 26.1 40.4 55.7 56.8 36.2 32.9 14.3 33.6 46.7 26.9 42.5 34.2 22.6 31.0 33.1 37.7 15.3 14.0 20.8 34.0 15.8 33.7 25.0 8.2 37.0 20.1 27.3 24.3 17.0 30.2 22.7 25.2 20.5 31.0 30.0 28.4 14.5 16.6 51.1 46.7 27.1 17.8 18.6 23.9 26.5 32.9 25.6 46.9 33.1 30.0 8.0 1.9 4.6 2.1 2.9 2.9 2.6 3.8 2.2 1.9 2.8 4.5 3.1 5.2 2.1 3.1 2.0 5.1 1.4 17.9 20.4 23.5 26.1 17.1 17.5 17.6 17.4 18.3 18.5 17.0 28.1 35.9 44.8 22.2 31.6 48.9 67.3 38.0 17.0 50.1 25.1 36.5 21.6 21.6 12.8 15.4 22.0 10.4 33.0 42.4 54.8 41.1 17.9 41.2 26.8 29.0 38.3 23.9 50.7 30.4 18.8 41.7 42.8 17.3 34.7 28.5 20.4 32.2 28.5 23.3 37.0 29.8 23.9 22.4 36.1 41.5 24.6 74.6 33.3 42.7 37.5 36.5 45.4 20.6 33.7 58.1 19.1 25.7 74.9 33.6 40.2 38.3 29.2 19.9 24.3 59.2 46.1 52.7 52.5 58.9 40.9 56.1 28.5 44.9 22.7 23.1 38.5 FBXL4 "FBL4, FBL5" ENSG00000112234 "F-box and leucine rich repeat protein 4" Q9UKA2 6 98868535-98948006 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 97.0;Oligodendrocytes: 94.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029140, CAB033362" Approved Supported "Nuclear speckles" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 1: Thyroid gland - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 68: Oligodendrocytes - Mixed function" "Nuclear speckles" "CAB033362: AB_2103974, HPA029140: AB_10611967" "unprognostic (1.24e-1)" "unprognostic (5.10e-2)" "unprognostic (1.10e-2)" "unprognostic (1.42e-1)" "unprognostic (3.34e-2)" "unprognostic (1.66e-1)" "unprognostic (2.03e-1)" "unprognostic (3.10e-1)" "unprognostic (2.79e-1)" "unprognostic (2.68e-1)" "unprognostic (4.53e-2)" "unprognostic (1.14e-1)" "unprognostic (1.05e-2)" "unprognostic (1.09e-1)" "unprognostic (1.70e-1)" "unprognostic (1.65e-1)" "unprognostic (2.62e-1)" 5.8 8.0 5.9 5.3 8.4 5.1 7.7 7.6 5.5 7.0 5.5 6.2 5.9 6.9 11.2 5.3 7.7 6.6 5.9 4.6 7.1 13.1 15.7 5.9 6.1 8.0 8.3 8.2 9.4 12.7 4.8 6.8 8.4 8.0 6.9 5.1 9.9 6.6 9.4 5.7 5.8 6.2 7.2 5.3 7.4 4.1 7.4 9.0 12.2 7.2 6.4 5.7 5.3 11.0 5.7 9.0 7.6 10.2 12.5 22.8 8.2 12.7 10.7 7.3 10.3 4.1 10.7 13.1 11.5 10.6 12.8 8.1 8.8 9.2 11.1 21.4 7.2 9.3 6.2 9.4 9.7 11.5 8.9 13.0 16.4 6.6 18.4 20.4 9.5 10.2 12.6 10.1 13.4 5.6 4.3 5.5 4.0 7.5 5.5 14.6 5.2 10.7 13.9 8.2 9.5 7.7 6.7 8.9 12.2 9.2 6.6 8.2 13.3 8.4 3.7 11.9 9.3 3.4 3.4 5.5 10.5 10.4 10.2 18.4 4.7 13.0 4.6 4.5 6.1 7.1 4.6 4.6 3.8 5.7 5.9 5.6 5.9 4.3 6.0 2.5 6.1 3.9 5.9 8.4 7.6 5.5 4.6 7.1 8.0 8.3 8.4 7.2 7.4 11.0 12.2 19.2 11.9 42.7 14.2 9.7 8.2 9.0 12.0 14.9 9.1 8.3 16.2 5.7 8.8 36.8 22.9 10.1 9.5 9.8 19.6 9.7 5.4 10.6 14.5 10.8 7.2 20.2 46.9 11.0 10.7 13.7 14.3 7.9 8.9 20.8 11.4 19.4 8.9 10.1 58.3 13.7 8.2 12.3 6.4 2.1 19.0 11.8 5.4 41.2 14.9 10.6 12.3 97.0 94.4 7.5 9.8 12.8 8.8 13.9 12.5 11.8 11.3 13.3 13.1 12.7 10.0 4.1 6.4 12.4 8.5 9.9 9.3 16.9 10.4 8.2 FBXL7 "FBL6, FBL7, KIAA0840" ENSG00000183580 "F-box and leucine rich repeat protein 7" Q9UJT9 5 15500180-15939795 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 976.2;Inhibitory neurons: 295.1;Oligodendrocyte precursor cells: 335.8;Oligodendrocytes: 766.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA055464 Uncertain NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA055464: AB_2682822" "unprognostic (3.03e-1)" "unprognostic (1.66e-1)" "unprognostic (1.18e-2)" "unprognostic (3.34e-1)" "unprognostic (1.50e-1)" "unprognostic (4.93e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (4.54e-2)" "unprognostic (1.46e-1)" "unprognostic (1.91e-1)" "unprognostic (2.10e-1)" "unprognostic (6.41e-2)" "unprognostic (4.29e-3)" "unprognostic (3.42e-3)" "unprognostic (1.32e-1)" "prognostic unfavorable (6.69e-4)" "unprognostic (1.94e-3)" 17.5 22.7 16.9 3.7 19.5 0.0 13.9 16.0 15.9 19.1 15.9 17.2 2.0 26.4 10.3 9.7 15.8 8.4 17.0 15.5 14.2 4.7 2.1 9.6 2.6 19.7 16.5 26.8 1.9 1.0 4.7 6.6 16.1 13.3 5.2 4.3 5.6 19.5 4.0 5.0 6.8 24.6 15.1 5.0 10.2 4.4 18.4 2.4 8.2 5.7 2.1 16.6 13.1 22.3 0.1 1.4 16.1 23.5 13.1 10.0 0.0 14.1 17.0 9.9 10.3 0.0 0.0 0.0 0.0 21.7 10.2 0.0 8.1 5.2 9.8 0.0 1.1 0.0 0.0 0.0 5.1 0.0 0.0 11.8 0.0 8.0 0.7 12.1 23.2 0.0 0.0 6.1 7.5 0.0 0.0 0.0 5.4 0.0 2.6 0.0 11.4 0.1 0.0 0.0 4.7 15.9 0.0 4.9 15.3 14.5 0.0 0.0 22.9 20.6 4.1 11.7 6.3 0.0 0.0 0.0 11.4 0.0 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 19.5 16.0 15.9 15.5 14.2 19.7 16.5 16.1 15.1 18.4 22.3 21.4 3.2 1.9 976.2 0.3 2.4 2.7 2.4 2.2 3.2 0.9 1.1 11.8 0.0 1.7 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.4 2.0 11.8 16.7 0.0 0.0 3.7 0.0 0.1 15.9 0.0 2.0 1.3 13.1 15.4 0.2 0.8 30.3 295.1 0.0 0.0 0.6 2.7 0.7 30.1 0.5 5.4 146.1 0.0 2.4 0.0 335.8 766.0 0.0 0.0 41.3 1.2 3.1 0.0 1.2 3.8 2.5 6.6 16.1 8.1 1.4 2.1 1.5 1.7 0.0 0.3 20.7 0.0 2.4 FBXO28 "CENP-30, Fbx28, FLJ10766, KIAA0483" ENSG00000143756 "F-box protein 28" Q9NVF7 1 224114111-224162047 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003289 Approved Supported "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 17: WM-115 - Nervous system development" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Focal adhesion sites" "HPA003289: AB_2666879" "unprognostic (4.91e-2)" "unprognostic (5.57e-2)" "unprognostic (1.78e-2)" "unprognostic (1.03e-1)" "unprognostic (1.33e-2)" "unprognostic (1.43e-1)" "unprognostic (2.12e-1)" "unprognostic (8.25e-2)" "unprognostic (2.03e-1)" "unprognostic (7.09e-2)" "unprognostic (5.09e-3)" "unprognostic (2.60e-1)" "unprognostic (1.98e-3)" "unprognostic (9.46e-2)" "unprognostic (1.71e-1)" "unprognostic (1.41e-1)" "unprognostic (2.61e-1)" 10.9 7.5 6.5 8.3 7.3 8.9 12.3 8.8 10.5 10.9 7.4 10.3 8.5 10.0 7.9 12.4 8.2 9.5 8.1 7.6 9.1 13.6 17.4 8.9 10.5 8.5 7.4 11.3 7.6 13.7 4.4 9.0 8.8 10.0 10.6 8.3 7.9 8.5 12.5 21.1 7.7 9.8 8.0 8.9 8.5 7.8 7.8 10.9 9.8 14.2 10.6 11.5 9.0 8.9 24.6 10.6 16.2 17.4 16.6 19.0 26.7 24.3 19.7 16.0 15.2 14.9 18.7 11.8 24.4 22.3 10.3 20.9 24.2 23.4 27.4 17.0 27.0 15.0 12.8 10.7 20.7 28.3 18.8 18.6 27.7 23.2 41.9 18.8 27.1 15.0 24.8 16.4 29.1 8.1 14.9 14.4 38.6 32.3 22.8 15.7 23.1 22.3 30.2 16.1 26.2 28.1 25.1 38.0 27.4 16.9 20.2 28.2 31.2 19.8 15.0 25.0 46.1 17.8 22.3 18.0 24.5 13.7 39.3 7.4 6.5 11.8 5.8 6.0 7.2 8.9 5.9 6.8 7.8 9.0 5.9 6.6 4.2 8.6 6.9 3.5 8.8 4.6 6.5 7.3 8.8 10.5 7.6 9.1 8.5 7.4 8.8 8.0 7.8 8.9 15.0 6.4 10.6 22.5 16.8 34.3 25.5 11.3 9.6 20.5 14.7 11.7 11.4 7.2 13.5 11.0 22.9 14.2 12.3 17.2 9.8 13.2 30.3 15.9 13.0 16.4 18.5 17.4 48.8 11.5 13.1 12.7 7.1 22.9 14.0 12.6 14.3 23.4 13.9 18.5 43.8 12.7 14.2 17.7 16.3 14.8 13.1 16.8 28.4 34.7 16.4 12.6 7.2 45.8 43.7 17.7 12.2 13.2 15.4 21.5 12.0 22.8 11.5 18.6 13.1 14.9 12.7 24.7 26.8 17.2 39.1 23.0 18.9 10.9 14.6 30.7 FCGR2A "CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, IGFR2" ENSG00000143226 "Fc fragment of IgG receptor IIa" P12318 1 161505430-161524013 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 101.7;placenta: 107.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 178.2;Kupffer cells: 159.1;Langerhans cells: 336.6;Macrophages: 305.0;monocytes: 97.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 2322.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 2322.4" "Cell line enhanced" "Detected in some" "HEL: 29.4;HMC-1: 56.2;K-562: 17.9;NB-4: 15.8;THP-1: 61.9;U-937: 26.7" "HPA010718, HPA010776, HPA014730" Enhanced Supported "Golgi apparatus,Plasma membrane" NA NA 46000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Golgi apparatus" "HPA010718: AB_1078463, HPA010776: , HPA014730: AB_2669074" "unprognostic (2.57e-2)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (4.12e-2)" "unprognostic (5.89e-2)" "unprognostic (6.17e-2)" "unprognostic (1.24e-2)" "unprognostic (1.17e-1)" "unprognostic (7.63e-2)" "unprognostic (1.17e-3)" "unprognostic (2.43e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (6.49e-7)" "unprognostic (8.85e-3)" "unprognostic (6.47e-3)" "unprognostic (1.54e-1)" "unprognostic (3.42e-2)" 68.0 24.8 7.3 101.7 6.6 48.6 13.3 8.0 12.1 18.1 13.9 16.0 8.1 7.3 4.3 11.7 14.6 36.8 11.5 6.5 11.5 12.7 12.3 77.5 16.1 15.1 11.4 7.2 12.7 8.5 7.6 107.3 13.3 6.1 21.0 2.3 9.9 9.6 2.6 3.5 10.8 40.9 11.9 61.8 10.1 4.4 13.8 9.8 6.4 10.2 7.7 68.3 5.2 21.8 0.0 0.0 0.0 2.4 0.0 0.3 0.0 0.0 0.5 0.0 0.1 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 29.4 0.3 0.0 0.7 8.6 56.2 0.5 0.0 0.0 0.0 0.7 0.1 0.0 17.9 0.5 0.0 0.0 0.4 15.8 0.0 0.0 1.1 0.2 1.2 8.1 0.0 0.0 0.1 0.0 0.0 0.0 4.6 0.0 0.0 61.9 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.7 0.4 26.7 6.6 2.4 358.3 421.8 0.7 268.4 1.0 3.2 0.5 0.4 89.9 1.7 0.4 0.7 2322.4 0.4 232.7 3.8 0.9 170.3 7.3 6.6 8.0 12.1 6.5 11.5 15.1 11.4 13.3 11.9 13.8 21.8 2.3 22.4 49.1 0.0 8.6 8.7 0.9 0.3 1.2 0.4 1.1 3.8 1.8 2.8 12.1 0.0 0.0 1.0 3.4 0.1 9.8 0.2 38.2 0.1 0.8 15.6 0.0 3.0 0.1 0.6 1.6 8.9 1.1 0.1 30.4 0.1 3.9 2.1 178.2 0.0 0.1 0.0 0.0 159.1 336.6 66.5 1.5 305.0 17.8 12.2 97.3 0.5 7.2 1.0 0.6 0.5 0.0 0.0 4.6 0.3 0.0 9.6 3.7 0.2 6.6 1.5 6.0 0.4 0.6 0.8 7.7 1.6 4.8 0.2 0.1 0.4 FCGR2B "CD32, CD32B, FCG2, FCGR2" ENSG00000072694 "Fc fragment of IgG receptor IIb" P31994 1 161663147-161678654 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "IgG-binding protein, Receptor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "placenta: 398.2" "Cell type enhanced" "Detected in many" "B-cells: 75.0;Hepatic stellate cells: 333.8;Langerhans cells: 244.0;Macrophages: 145.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 327.2;memory B-cell: 202.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 24.9;HMC-1: 31.2;NB-4: 7.3;RPMI-8226: 11.7" "CAB007796, HPA014730" Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB007796: AB_562288, HPA014730: AB_2669074" "unprognostic (1.58e-1)" "unprognostic (5.14e-2)" "unprognostic (3.32e-3)" "unprognostic (3.12e-2)" "unprognostic (6.79e-3)" "unprognostic (4.05e-3)" "unprognostic (1.27e-1)" "unprognostic (4.65e-3)" "unprognostic (1.91e-1)" "unprognostic (4.72e-2)" "unprognostic (2.89e-2)" "unprognostic (3.49e-1)" "prognostic unfavorable (8.82e-4)" "unprognostic (3.51e-2)" "unprognostic (6.36e-2)" "unprognostic (4.31e-1)" "unprognostic (3.37e-1)" 30.4 7.5 0.9 12.2 1.3 1.7 15.4 1.3 3.3 9.7 4.2 10.3 3.0 2.6 2.8 11.4 4.4 13.0 7.9 0.7 1.1 4.2 42.4 21.7 15.8 4.5 1.1 4.8 4.7 2.8 1.4 398.2 2.2 1.8 11.0 1.1 7.0 2.8 2.2 4.8 16.0 16.6 2.2 25.5 4.9 2.5 1.4 7.4 4.2 13.7 29.6 18.7 3.1 5.8 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 31.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 7.3 0.1 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.1 0.1 0.0 0.0 2.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 2.8 0.0 327.2 8.5 26.4 1.4 9.7 0.6 202.8 0.7 1.1 72.4 160.4 0.1 1.4 53.6 0.7 9.5 0.1 0.1 13.0 0.9 1.3 1.3 3.3 0.7 1.1 4.5 1.1 2.2 2.2 1.4 5.8 2.2 0.0 3.9 0.0 75.0 5.4 0.1 0.0 0.0 0.0 0.3 0.9 2.1 2.8 1.3 0.0 0.0 0.2 5.6 0.0 0.0 0.0 4.8 0.0 0.0 49.8 0.0 3.2 0.0 0.0 0.2 1.7 1.1 0.0 2.5 0.2 333.8 8.2 7.6 0.0 0.0 0.0 0.0 47.4 244.0 4.2 0.6 145.5 23.2 0.0 9.5 0.0 5.2 0.0 0.1 0.0 0.0 0.0 45.4 0.0 0.0 0.3 0.0 0.0 0.0 1.7 2.5 0.3 0.2 0.7 3.1 0.4 5.8 0.1 0.1 0.0 FCN3 "FCNH, HAKA1" ENSG00000142748 "Ficolin 3" O75636 1 27369110-27374824 "Disease related genes, Plasma proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "liver: 278.3;lung: 724.6" "Cell type enriched" "Detected in some" 16 "Hepatic stellate cells: 2828.6" "Cancer enhanced" "Detected in many" "renal cancer: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB025945 Approved "Secreted to blood" NA NA 22800000000 14000000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB025945: " "unprognostic (1.59e-1)" "unprognostic (5.25e-2)" "unprognostic (1.55e-2)" "unprognostic (8.27e-2)" "unprognostic (1.45e-3)" "unprognostic (1.27e-2)" "unprognostic (1.87e-3)" "unprognostic (1.21e-1)" "unprognostic (6.28e-4)" "unprognostic (7.07e-2)" "unprognostic (2.86e-2)" "unprognostic (3.23e-2)" "unprognostic (3.87e-3)" "unprognostic (4.14e-2)" "unprognostic (1.02e-1)" "unprognostic (6.97e-2)" "unprognostic (1.61e-2)" 62.6 35.9 1.1 5.7 1.0 0.0 40.8 1.1 1.6 2.7 10.0 4.1 0.8 3.9 0.1 2.8 3.0 1.6 62.1 1.4 1.1 55.2 278.3 724.6 4.3 1.2 1.2 2.4 12.5 2.7 6.6 22.6 1.2 5.3 0.5 0.0 2.5 0.5 9.0 1.9 6.7 1.8 1.2 11.3 8.4 2.4 1.2 0.4 20.4 7.5 0.3 3.0 1.9 1.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.0 1.1 1.6 1.4 1.1 1.2 1.2 1.2 1.2 1.2 1.0 94.1 0.0 9.3 0.0 16.6 0.8 0.6 0.5 0.6 0.0 0.8 2.8 2.4 52.9 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.1 1.5 0.4 0.2 155.1 0.0 136.4 0.1 0.0 0.0 3.8 0.5 0.2 3.8 0.0 2828.6 31.8 0.3 0.0 0.1 0.0 2.0 168.6 0.3 2.7 3.4 2.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.6 0.0 0.1 5.1 0.0 0.0 1.0 2.7 0.5 0.5 1.0 1.1 0.0 4.9 0.5 0.0 0.3 FCRL3 "CD307c, FCRH3, IFGP3, IRTA3, SPAP2, SPAP2a, SPAP2b, SPAP2c, SPAP2d, SPAP2e" ENSG00000160856 "Fc receptor like 3" Q96P31 1 157674321-157700769 "CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 49.5" "Cell type enhanced" "Detected in some" "B-cells: 54.3;dendritic cells: 21.2;Early spermatids: 8.0;Late spermatids: 9.1;NK-cells: 30.9;T-cells: 12.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive B-cell: 35.3" "Group enriched" "Detected in many" 54 "B-cells: 35.3;NK-cells: 20.4;T-cells: 19.0" "Cell line enriched" "Detected in some" 7 "Daudi: 9.9" "Low region specificity" "Detected in some" HPA048022 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA048022: AB_2732541" "unprognostic (6.73e-3)" "unprognostic (5.06e-4)" "unprognostic (1.13e-2)" "unprognostic (2.08e-4)" "unprognostic (3.86e-1)" "unprognostic (1.74e-5)" "unprognostic (1.09e-2)" "unprognostic (4.29e-3)" "unprognostic (3.69e-3)" "unprognostic (2.46e-4)" "unprognostic (1.13e-1)" "unprognostic (2.55e-2)" "unprognostic (2.01e-4)" "unprognostic (1.55e-1)" "unprognostic (1.29e-1)" "unprognostic (2.21e-1)" "unprognostic (6.69e-2)" 0.4 0.0 0.0 14.1 0.0 1.1 0.1 0.0 0.0 0.1 0.0 1.1 0.3 0.2 0.1 0.1 0.1 1.0 0.2 0.0 0.0 0.2 0.8 0.9 49.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 1.2 0.0 0.8 0.0 0.1 0.0 8.7 0.1 0.0 27.5 1.5 0.2 0.0 4.6 0.4 0.1 36.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 19.0 0.0 1.8 30.3 2.6 13.2 0.0 35.3 0.2 8.3 0.4 20.4 0.0 0.0 11.3 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 54.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 21.2 0.0 0.0 0.0 8.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.1 0.0 0.0 1.2 0.0 9.1 0.0 0.4 0.0 1.0 0.9 0.0 30.9 0.5 0.0 0.0 1.1 0.0 3.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 12.4 0.0 0.0 0.0 FCRL5 "BXMAS1, CD307e, FCRH5, IRTA2" ENSG00000143297 "Fc receptor like 5" Q96RD9 1 157513377-157552515 "CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 36.3" "Group enriched" "Detected in some" 5 "B-cells: 102.6;Early spermatids: 63.6;Plasma cells: 190.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "memory B-cell: 13.0;naive B-cell: 14.2" "Lineage enriched" "Detected in single" 17 "B-cells: 14.2" "Group enriched" "Detected in some" 5 "U-266/70: 3.4;U-698: 7.4" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 169000000 65000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.30e-3)" "unprognostic (3.51e-2)" "unprognostic (7.59e-3)" "unprognostic (1.57e-2)" "unprognostic (9.41e-3)" "unprognostic (4.32e-5)" "unprognostic (2.61e-2)" "unprognostic (6.93e-2)" "unprognostic (7.40e-2)" "unprognostic (7.66e-3)" "unprognostic (4.01e-1)" "unprognostic (1.39e-1)" "unprognostic (9.51e-10)" "unprognostic (1.20e-1)" "unprognostic (4.40e-1)" "unprognostic (8.99e-2)" "unprognostic (2.78e-1)" 0.4 0.4 0.0 13.8 0.0 2.3 2.4 0.0 0.1 0.6 0.0 5.5 5.8 0.1 0.3 0.8 0.4 1.2 0.3 0.0 0.0 0.4 0.3 1.1 24.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 4.4 0.0 3.8 0.3 0.0 0.0 5.0 0.1 0.1 15.1 4.5 0.6 0.0 4.1 0.6 0.0 36.3 4.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.3 102.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 3.1 2.9 0.1 0.0 0.0 63.6 0.0 0.0 0.1 0.0 1.3 0.1 0.0 0.2 0.3 1.1 0.0 1.3 0.0 0.4 1.8 0.3 0.0 0.1 0.0 0.0 0.3 0.3 10.1 0.3 0.2 23.2 0.0 0.5 0.0 0.0 0.5 0.2 0.0 0.0 0.0 190.5 0.2 0.0 0.1 0.0 0.0 6.6 0.0 0.3 1.2 0.1 0.1 0.0 0.7 5.7 0.0 0.6 0.0 FER "PPP1R74, TYK3" ENSG00000151422 "FER tyrosine kinase" P16591 5 108747841-109196841 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in all" 6 "Alveolar cells type 1: 80.1;Astrocytes: 207.3;Early spermatids: 158.1;Excitatory neurons: 266.3;granulocytes: 95.5;Inhibitory neurons: 313.8;Late spermatids: 182.4;Microglial cells: 227.7;Oligodendrocyte precursor cells: 284.0;Oligodendrocytes: 216.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 5 "RPMI-8226: 91.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007641, CAB022464" Approved Supported Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 25: RPMI-8226 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "CAB022464: , HPA007641: AB_1078845" "unprognostic (1.72e-1)" "unprognostic (1.66e-2)" "unprognostic (1.74e-1)" "unprognostic (2.46e-3)" "unprognostic (4.72e-2)" "unprognostic (5.65e-2)" "unprognostic (6.81e-2)" "unprognostic (7.39e-2)" "unprognostic (1.05e-1)" "unprognostic (8.36e-3)" "unprognostic (7.36e-2)" "unprognostic (8.05e-2)" "prognostic favorable (5.55e-4)" "unprognostic (3.83e-3)" "unprognostic (3.22e-1)" "unprognostic (1.03e-1)" "unprognostic (3.99e-3)" 4.2 3.7 3.4 3.0 3.2 1.6 3.6 2.8 3.4 3.8 0.6 3.9 1.7 3.7 2.9 4.2 3.0 3.3 3.0 3.1 3.9 3.5 2.3 3.7 1.4 3.6 3.7 4.6 1.9 9.4 2.5 4.2 3.8 3.0 2.4 5.7 2.5 3.9 1.3 4.5 2.0 4.9 4.1 2.7 2.2 6.7 3.1 2.8 6.4 2.0 2.0 3.5 3.2 5.0 9.8 3.4 11.0 18.0 6.6 10.1 7.2 11.4 11.0 6.5 7.6 19.0 5.5 15.3 6.9 13.8 8.4 6.3 6.2 14.4 14.7 6.5 8.4 9.8 14.5 7.0 4.4 5.6 8.2 6.2 7.9 15.8 17.5 6.4 9.8 14.6 12.9 11.1 8.4 2.7 4.4 1.7 1.6 0.9 7.0 3.3 10.7 91.7 6.4 3.3 3.8 5.6 18.6 1.0 11.4 7.0 4.4 2.4 14.7 12.5 10.2 6.5 9.0 9.4 14.9 5.9 7.4 1.9 6.0 8.9 3.7 4.6 1.2 2.5 2.1 10.3 0.7 1.4 2.3 3.4 1.2 1.5 0.3 1.1 2.0 4.5 1.7 0.9 3.4 3.2 2.8 3.4 3.1 3.9 3.6 3.7 3.8 4.1 3.1 5.0 23.8 80.1 28.3 207.3 9.5 29.2 15.8 9.5 25.6 17.6 6.6 8.5 21.9 10.0 21.8 14.7 18.8 3.9 7.5 4.9 1.9 13.6 158.1 13.1 17.2 19.7 8.4 10.7 266.3 6.0 10.7 31.4 16.8 12.6 95.5 21.8 18.9 2.3 8.2 18.5 313.8 4.5 8.2 9.5 13.4 182.4 19.3 14.1 14.2 227.7 12.0 10.5 4.1 284.0 216.0 9.1 4.7 17.7 13.7 12.1 1.7 6.9 27.9 16.3 6.6 30.7 23.8 7.7 11.5 13.2 17.6 3.1 10.4 10.2 4.1 6.9 FEZ1 UNC-76 ENSG00000149557 "Fasciculation and elongation protein zeta 1" Q99689 11 125442881-125592568 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 176.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 109.8;Horizontal cells: 166.5;Oligodendrocytes: 246.6" "Cancer enriched" "Detected in all" 10 "glioma: 68.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 23.4;MAIT T-cell: 15.5" "Lineage enriched" "Detected in many" 23 "T-cells: 23.4" "Cell line enhanced" "Detected in many" "AF22: 48.3;HBEC3-KT: 66.0;NTERA-2: 68.6;SCLC-21H: 54.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038490, HPA076844" Approved Approved Microtubules,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 5: NTERA-2 - Transcription" "Cluster 62: Horizontal cells - Visual perception" "Microtubules, Cytosol" "HPA038490: AB_10672647, HPA076844: " "unprognostic (5.68e-2)" "prognostic unfavorable (9.06e-5)" "unprognostic (7.40e-2)" "unprognostic (3.73e-1)" "unprognostic (1.08e-1)" "unprognostic (2.30e-2)" "unprognostic (2.72e-1)" "unprognostic (2.06e-1)" "unprognostic (8.30e-2)" "unprognostic (2.08e-1)" "unprognostic (2.81e-1)" "unprognostic (5.63e-2)" "prognostic unfavorable (2.16e-6)" "unprognostic (2.14e-2)" "unprognostic (2.68e-1)" "unprognostic (3.99e-2)" "unprognostic (1.02e-1)" 16.9 5.4 96.8 2.9 144.0 0.9 11.3 145.5 120.6 21.8 53.1 39.3 1.7 23.5 2.3 6.2 14.7 6.9 37.4 95.5 120.4 6.8 5.5 34.2 1.9 145.6 136.9 12.7 2.5 1.9 17.6 3.8 138.9 15.4 3.3 18.7 6.4 7.6 5.9 7.9 12.6 8.3 134.8 8.8 15.9 12.7 126.7 0.5 10.2 3.0 1.4 26.5 16.9 176.6 0.3 0.0 48.3 0.2 39.2 25.3 0.0 10.3 14.6 3.8 0.6 0.2 0.3 0.1 16.3 21.1 11.4 0.5 31.2 66.0 2.4 2.3 0.5 37.6 0.1 0.0 25.3 0.0 0.6 23.1 17.6 11.5 29.3 0.4 32.0 0.0 4.5 0.6 3.8 1.5 0.2 0.0 68.6 0.5 1.2 0.0 0.1 0.2 0.0 30.3 54.3 5.5 0.3 0.1 1.4 27.3 4.9 26.4 19.3 0.4 2.4 0.2 11.1 0.6 0.5 0.1 7.9 0.0 26.6 0.2 0.8 0.0 23.4 0.1 15.5 0.1 0.9 5.1 0.4 0.0 0.6 5.5 0.2 1.0 0.0 0.1 0.0 4.4 96.8 144.0 145.5 120.6 95.5 120.4 145.6 136.9 138.9 134.8 126.7 176.6 4.9 0.0 5.2 53.2 0.8 8.0 4.9 96.9 6.2 23.1 0.5 10.3 109.8 2.8 9.6 0.0 2.1 8.0 23.3 0.1 27.4 2.8 68.6 0.8 14.2 13.9 5.4 0.0 41.0 0.4 1.2 43.0 0.5 0.5 0.0 11.1 58.9 1.0 91.6 166.5 48.7 0.0 16.2 24.9 15.5 65.9 25.4 2.3 78.2 12.2 1.9 97.1 74.2 32.2 246.6 0.3 0.0 35.3 0.9 12.7 0.0 2.1 3.8 17.8 19.7 25.4 35.6 28.8 7.7 0.2 5.5 4.2 7.8 5.5 0.1 3.5 FGA ENSG00000171560 "Fibrinogen alpha chain" P02671 4 154583128-154590745 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Blood coagulation, Hemostasis, Immunity, Innate immunity" "Amyloidosis, Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 388 "liver: 18396.9" "Cell type enriched" "Detected in some" 41 "Hepatocytes: 17365.8" "Cancer enriched" "Detected in many" 43 "liver cancer: 2431.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "Hep G2: 429.3" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016776, HPA051370, HPA064755" Supported Enhanced "Endoplasmic reticulum" "Secreted to blood" NA NA 407000000 140000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "CAB016776: , HPA051370: AB_2681458, HPA064755: AB_2685345" "unprognostic (5.95e-2)" "unprognostic (6.25e-2)" "unprognostic (2.02e-1)" "unprognostic (5.68e-2)" "prognostic favorable (7.33e-4)" "unprognostic (1.29e-3)" "unprognostic (1.84e-1)" "prognostic unfavorable (4.23e-6)" "unprognostic (4.20e-1)" "unprognostic (1.41e-1)" 2.1 1.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.5 0.0 0.5 0.0 0.6 0.6 0.7 0.9 13.2 1.2 0.0 0.0 18.8 18396.9 5.3 0.1 0.0 0.0 0.7 18.8 0.0 0.5 0.9 0.0 0.4 0.0 0.0 0.5 0.0 0.5 0.6 0.9 0.0 0.0 9.9 47.4 3.7 0.0 0.1 0.4 0.0 0.1 0.6 0.7 0.0 0.0 28.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.1 0.0 2.7 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 3.4 0.1 429.3 0.0 6.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.2 0.0 0.5 0.1 0.0 0.5 6.1 0.0 0.0 0.5 0.2 0.1 3.5 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.3 0.0 0.0 1.0 0.0 1.9 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 27.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 414.6 3.2 0.0 0.0 0.0 0.0 0.0 1.9 38.6 28.3 0.1 0.2 8.1 0.0 205.9 0.0 1.8 0.1 0.1 1.1 1.3 0.0 0.0 238.8 17365.8 0.1 0.0 0.0 0.0 0.0 328.3 0.0 46.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 1.2 0.0 0.0 0.0 2.3 9.5 0.0 0.0 0.0 0.1 17.4 0.7 0.0 0.0 0.1 17.6 0.0 0.0 0.0 FGB ENSG00000171564 "Fibrinogen beta chain" P02675 4 154563011-154572807 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Blood coagulation, Hemostasis, Immunity, Innate immunity" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 373 "liver: 17944.9" "Cell type enriched" "Detected in some" 40 "Hepatocytes: 17273.6" "Cancer enriched" "Detected in many" 42 "liver cancer: 2262.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "Hep G2: 249.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001900, HPA001901, CAB008624" Enhanced Enhanced "Endoplasmic reticulum" "Secreted to blood" NA NA 110000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "CAB008624: AB_1615610, HPA001900: AB_1078865, HPA001901: AB_1078864" "unprognostic (1.16e-1)" "unprognostic (3.89e-2)" "unprognostic (4.65e-2)" "unprognostic (3.44e-1)" "unprognostic (2.20e-3)" "unprognostic (1.42e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (5.72e-5)" "unprognostic (2.48e-2)" "unprognostic (7.91e-2)" 2.0 0.8 0.0 0.0 0.0 0.1 2.8 0.0 0.0 1.3 0.0 0.5 0.0 0.6 0.3 0.6 0.8 0.4 1.4 0.0 0.0 48.0 17944.9 0.5 0.1 0.0 0.0 0.6 3.3 0.0 0.5 1.0 0.0 0.4 0.0 0.0 0.4 0.0 0.5 0.5 1.2 0.0 0.0 12.1 6.8 0.5 0.0 0.3 0.4 0.0 0.1 0.5 0.7 0.0 0.0 20.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 2.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.2 0.1 249.9 0.0 5.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 1.7 0.2 0.0 0.6 0.0 0.0 0.2 3.8 0.0 0.0 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.8 0.0 0.9 0.0 2.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 39.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.6 251.6 0.0 3.7 0.0 0.0 0.0 0.0 1.9 10.6 0.5 0.6 0.8 13.1 1.8 302.1 0.0 3.8 0.2 0.0 0.0 5.9 0.0 0.0 318.1 17273.6 0.3 0.0 0.0 0.0 0.0 421.7 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 24.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 23.7 0.0 0.0 0.0 FGD2 ZFYVE4 ENSG00000146192 "FYVE, RhoGEF and PH domain containing 2" Q7Z6J4 6 37005646-37029069 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.7" "Cell type enhanced" "Detected in many" "B-cells: 53.7;dendritic cells: 29.7;Kupffer cells: 118.2;Langerhans cells: 49.3;Macrophages: 52.0;Microglial cells: 43.1;monocytes: 51.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 22.3;intermediate monocyte: 64.8;memory B-cell: 23.2;myeloid DC: 35.0;naive B-cell: 18.6;non-classical monocyte: 70.5;plasmacytoid DC: 27.4" "Group enriched" "Detected in many" 18 "B-cells: 23.2;dendritic cells: 35.0;monocytes: 70.5" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.7;Daudi: 11.5;HDLM-2: 11.3;U-698: 9.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029145, HPA049692" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA029145: AB_10601321, HPA049692: AB_2680852" "unprognostic (3.54e-2)" "unprognostic (1.40e-4)" "unprognostic (5.69e-3)" "unprognostic (2.29e-1)" "unprognostic (1.27e-1)" "unprognostic (1.67e-4)" "unprognostic (7.97e-2)" "unprognostic (1.58e-2)" "unprognostic (2.47e-2)" "unprognostic (2.78e-1)" "unprognostic (3.39e-2)" "unprognostic (2.82e-1)" "unprognostic (1.15e-2)" "unprognostic (3.91e-1)" "unprognostic (1.02e-2)" "unprognostic (3.88e-1)" "unprognostic (7.10e-2)" 6.1 3.3 1.0 14.8 1.3 6.0 2.6 1.2 1.3 1.5 2.3 3.4 3.7 1.3 1.5 2.4 2.8 4.1 1.6 1.0 1.6 1.4 2.5 8.0 22.5 3.2 1.7 1.0 1.3 0.3 1.1 2.7 1.9 1.5 2.7 0.1 2.3 1.8 0.6 2.1 11.1 4.7 2.1 39.7 3.8 0.6 2.1 5.5 2.7 0.9 9.8 4.5 1.6 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 11.5 0.0 0.0 0.0 0.4 0.0 0.0 0.3 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 1.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.1 22.3 2.3 0.1 64.8 0.1 23.2 0.0 0.0 35.0 18.6 0.0 0.0 0.3 0.4 70.5 27.4 0.1 7.5 1.0 1.3 1.2 1.3 1.0 1.6 3.2 1.7 1.9 2.1 2.1 2.0 0.3 6.4 7.4 0.0 53.7 2.0 3.0 1.0 0.6 0.3 0.7 0.6 3.2 2.8 0.5 0.0 0.0 0.3 29.7 0.3 0.0 2.8 11.9 0.5 0.2 1.2 0.0 1.3 0.1 0.9 0.4 1.0 1.5 1.2 7.6 0.0 2.5 0.6 17.7 0.0 0.2 0.1 4.1 118.2 49.3 2.1 1.5 52.0 1.8 43.1 51.8 0.4 2.1 0.5 0.2 1.0 3.9 0.0 14.2 1.6 0.1 0.2 3.2 0.2 0.0 2.3 0.5 0.0 0.1 3.3 2.3 0.4 3.0 0.1 0.4 5.6 FGD5 "FLJ00274, FLJ39957, ZFYVE23" ENSG00000154783 "FYVE, RhoGEF and PH domain containing 5" Q6ZNL6 3 14810853-14934571 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 51.3;Endothelial cells: 44.7;Hepatic stellate cells: 55.6;Microglial cells: 25.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 94.9;TIME: 81.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014436, HPA014536, HPA019191" Uncertain Supported "Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA014436: , HPA014536: AB_1848518, HPA019191: AB_1848519" "unprognostic (2.57e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (3.28e-2)" "unprognostic (2.02e-2)" "unprognostic (1.03e-3)" "unprognostic (1.08e-1)" "unprognostic (4.10e-2)" "unprognostic (6.34e-2)" "unprognostic (5.53e-2)" "unprognostic (1.46e-1)" "unprognostic (9.39e-2)" "unprognostic (6.84e-3)" "unprognostic (1.71e-2)" "unprognostic (3.46e-1)" "unprognostic (1.32e-2)" "prognostic favorable (7.50e-4)" 19.8 4.4 4.8 5.6 4.3 0.3 15.0 4.1 4.9 10.4 3.4 5.3 9.2 11.3 2.3 5.7 8.5 11.9 11.5 3.0 2.9 10.1 3.1 20.6 4.2 4.5 11.5 5.3 2.2 3.5 3.2 17.7 4.8 5.3 4.6 0.2 3.7 4.4 6.8 5.4 7.0 11.4 3.2 25.0 4.6 4.3 6.7 2.0 7.5 13.4 3.6 7.7 5.6 3.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 94.9 0.1 0.0 0.0 0.0 0.0 0.4 0.2 5.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.6 0.4 0.0 81.1 0.0 6.6 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 4.3 4.1 4.9 3.0 2.9 4.5 11.5 4.8 3.2 6.7 3.0 51.3 0.0 4.6 0.0 0.9 3.1 0.2 0.0 1.2 0.1 1.3 1.9 4.4 1.5 0.6 0.0 0.0 0.3 0.4 0.1 1.9 0.2 7.3 0.4 5.3 44.7 0.0 5.3 3.4 0.2 0.1 11.3 1.1 0.3 0.0 0.0 55.6 1.3 10.5 0.0 8.6 0.2 0.0 2.2 5.9 9.9 11.5 3.3 1.8 25.3 0.0 0.0 1.0 0.5 0.3 4.8 2.5 4.5 0.0 0.3 1.0 7.0 0.0 0.2 0.0 4.9 2.4 0.2 3.6 0.1 1.8 0.5 0.7 2.3 0.5 0.2 FGF13 "FGF2, FHF2, FLJ30672, LINC00889" ENSG00000129682 "Fibroblast growth factor 13" Q92913 X 138614727-139222777 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.0;parathyroid gland: 49.5;skeletal muscle: 67.3;tongue: 52.3" "Cell type enriched" "Detected in many" 6 "Inhibitory neurons: 432.5" "Cancer enhanced" "Detected in some" "prostate cancer: 2.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.7" "Lineage enriched" "Detected in single" 9 "granulocytes: 3.7" "Cell line enhanced" "Detected in many" "AF22: 43.0;fHDF/TERT166: 38.1;HAP1: 39.8;RPMI-8226: 34.4;U-2197: 69.3;WM-115: 37.5" "Low region specificity" "Detected in all" HPA002809 Supported Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA002809: AB_1078855" "unprognostic (3.23e-1)" "unprognostic (3.13e-2)" "unprognostic (5.42e-2)" "unprognostic (1.42e-2)" "unprognostic (1.87e-1)" "unprognostic (2.87e-3)" "unprognostic (9.92e-3)" "unprognostic (2.97e-3)" "unprognostic (4.92e-2)" "unprognostic (5.90e-3)" "unprognostic (5.22e-3)" "unprognostic (6.79e-2)" "unprognostic (4.96e-4)" "unprognostic (4.36e-3)" "unprognostic (1.22e-1)" "unprognostic (2.27e-1)" "unprognostic (7.48e-2)" 18.5 2.6 17.8 2.9 18.9 4.1 6.6 4.0 30.2 11.3 4.9 7.0 4.0 10.7 3.4 6.6 3.6 6.1 1.9 39.4 20.7 7.4 1.8 2.3 5.3 12.4 15.2 8.8 1.1 49.5 4.2 13.3 50.0 17.6 4.8 11.3 11.2 4.9 67.3 1.8 4.7 6.6 11.3 6.2 5.3 4.1 21.9 0.9 5.2 52.3 2.2 6.0 4.3 14.6 0.1 0.5 43.0 0.1 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.2 0.3 0.7 38.1 0.3 2.7 39.8 0.1 0.0 0.3 11.1 0.2 0.3 1.6 1.5 0.3 0.5 0.6 1.0 0.1 0.0 0.2 0.0 2.5 1.8 12.4 4.4 0.3 0.1 0.3 4.4 0.1 14.3 6.6 2.8 34.4 6.3 0.2 0.1 0.2 0.0 0.3 26.8 21.0 0.1 0.2 0.8 1.3 1.8 69.3 19.1 16.2 9.8 0.1 15.3 12.8 37.5 1.6 0.2 0.8 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 3.7 0.1 0.2 0.4 0.1 0.0 17.8 18.9 4.0 30.2 39.4 20.7 12.4 15.2 50.0 11.3 21.9 14.6 9.7 0.0 0.0 12.7 0.1 0.4 3.0 0.3 2.8 3.6 18.3 4.1 2.6 10.0 3.0 7.3 0.0 0.2 0.0 0.5 17.6 4.2 0.0 7.7 5.0 3.6 2.4 0.0 43.5 5.8 0.3 6.1 3.1 20.5 0.0 1.4 1.4 0.1 29.3 0.0 432.5 0.8 6.1 3.7 1.4 1.4 26.1 0.6 1.8 62.8 0.6 44.8 0.0 14.1 2.4 3.8 6.7 24.5 0.1 16.9 0.0 2.9 1.8 4.2 32.9 18.0 13.7 0.0 3.7 0.1 0.9 0.1 0.3 0.8 0.3 1.0 FGFBP2 KSP37 ENSG00000137441 "Fibroblast growth factor binding protein 2" Q9BYJ0 4 15960245-15969309 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 29.0;bone marrow: 54.6" "Group enriched" "Detected in many" 6 "dendritic cells: 486.6;NK-cells: 1627.2" "Group enriched" "Detected in many" 9 "glioma: 4.8;head and neck cancer: 13.1;lung cancer: 16.7;melanoma: 16.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 551.3;memory CD8 T-cell: 332.1" "Lineage enriched" "Detected in many" 8 "T-cells: 551.3" "Cell line enhanced" "Detected in some" "SK-MEL-30: 6.9;T-47d: 3.2;WM-115: 1.3" "Secreted to blood" NA NA 346000000 36000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (3.51e-3)" "unprognostic (8.81e-3)" "unprognostic (1.21e-1)" "unprognostic (2.54e-1)" "unprognostic (2.55e-2)" "unprognostic (1.54e-1)" "unprognostic (6.14e-2)" "unprognostic (1.35e-2)" "unprognostic (9.89e-2)" "unprognostic (1.76e-1)" "unprognostic (2.55e-2)" "unprognostic (3.33e-1)" "unprognostic (3.51e-2)" "unprognostic (1.87e-1)" "unprognostic (1.59e-2)" "unprognostic (9.61e-2)" "unprognostic (1.49e-2)" 29.0 1.5 0.9 0.4 1.0 54.6 12.7 0.8 1.5 0.6 0.8 11.8 0.1 0.5 7.2 0.6 0.7 0.9 23.6 1.0 1.1 0.5 1.2 8.5 2.9 0.9 0.8 0.4 0.2 0.3 0.2 0.5 0.9 1.4 0.9 1.1 8.6 0.9 1.1 21.0 2.0 0.3 0.8 14.0 1.7 8.6 0.9 5.3 1.1 3.6 1.0 2.8 1.8 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.1 0.0 0.0 0.2 0.0 0.0 6.9 0.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.3 3.5 0.8 2.4 551.3 1.3 5.2 0.8 128.6 332.1 0.9 0.4 47.3 314.1 8.4 64.9 1.6 2.1 0.9 371.2 0.9 1.0 0.8 1.5 1.0 1.1 0.9 0.8 0.9 0.8 0.9 0.9 2.6 0.0 5.3 0.0 2.6 9.6 0.0 0.2 0.0 0.0 1.5 1.7 1.5 5.7 1.4 5.5 8.4 0.6 486.6 0.1 0.0 0.7 1.3 0.9 0.1 2.2 0.0 3.6 0.0 0.0 0.0 19.9 0.5 0.3 3.8 60.3 6.1 0.6 0.0 0.0 0.0 0.4 0.0 4.9 12.0 3.0 0.0 2.2 46.2 0.0 5.8 1.4 1627.2 0.0 0.1 0.2 0.0 0.4 17.5 0.0 0.0 1.3 1.3 0.4 0.0 1.8 2.5 0.7 0.1 0.1 7.7 1.0 167.2 0.2 0.1 0.0 FGFRL1 ENSG00000127418 "Fibroblast growth factor receptor like 1" Q8N441 4 1009936-1026898 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 34.0;Granulosa cells: 30.9;Hepatocytes: 37.5;Muller glia cells: 94.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.1;non-classical monocyte: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-251 MG: 99.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026019, HPA068828" Approved Supported Vesicles No No "Cluster 7: Monocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" Vesicles "CAB026019: , HPA068828: AB_2686043" "unprognostic (1.30e-2)" "unprognostic (2.54e-2)" "unprognostic (6.27e-2)" "unprognostic (2.80e-2)" "unprognostic (1.23e-2)" "unprognostic (1.48e-1)" "unprognostic (2.62e-2)" "unprognostic (9.79e-2)" "unprognostic (4.87e-3)" "unprognostic (8.46e-2)" "unprognostic (2.01e-2)" "unprognostic (1.51e-1)" "unprognostic (2.36e-3)" "unprognostic (1.49e-1)" "unprognostic (7.80e-2)" "unprognostic (1.06e-2)" "unprognostic (1.96e-2)" 38.1 56.0 40.8 5.0 43.3 7.6 24.1 40.6 49.5 15.7 29.8 10.2 7.3 9.9 3.4 5.5 36.0 9.3 19.8 39.2 33.5 25.4 52.8 15.1 3.1 49.9 45.8 25.4 71.6 16.1 21.6 3.0 46.5 12.4 4.9 10.5 37.6 2.7 20.6 10.7 13.5 4.0 42.2 9.1 27.2 5.5 47.9 1.4 67.1 9.6 2.2 11.2 8.0 42.1 23.2 31.6 11.3 34.3 11.9 12.3 2.9 40.4 6.2 12.9 8.4 23.1 47.9 2.6 49.3 63.3 58.3 5.8 21.8 14.1 11.8 8.3 21.0 0.3 41.2 61.5 24.0 13.7 5.6 25.7 11.7 22.4 9.5 48.4 12.5 9.3 25.3 8.9 7.9 30.8 16.0 37.7 14.2 39.7 83.8 24.7 16.3 16.7 22.6 3.6 1.2 2.2 38.1 0.8 15.2 13.4 22.5 11.9 26.1 68.8 27.2 35.2 99.8 8.9 12.9 3.8 18.1 15.6 22.8 0.6 0.0 0.0 0.2 1.1 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.1 40.8 43.3 40.6 49.5 39.2 33.5 49.9 45.8 46.5 42.2 47.9 42.1 3.8 3.2 4.1 34.0 2.8 6.5 3.7 5.4 2.2 5.4 13.2 6.1 8.5 11.5 6.9 7.3 0.0 1.6 4.1 4.4 0.0 9.6 0.2 6.0 4.2 2.6 1.8 4.8 3.2 10.2 26.6 5.1 6.6 13.5 1.3 30.9 5.3 37.5 3.2 0.0 2.8 11.0 0.0 1.6 2.5 1.2 4.4 3.4 7.2 1.9 1.3 94.0 1.0 5.0 5.4 19.9 2.7 3.4 2.2 11.4 2.9 7.6 7.0 5.6 0.0 3.3 5.1 0.4 4.2 1.2 4.7 1.5 4.2 17.5 3.6 8.8 FGG ENSG00000171557 "Fibrinogen gamma chain" P02679 4 154604134-154612967 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 330 "liver: 16556.3" "Cell type enriched" "Detected in some" 16 "Hepatocytes: 10221.7" "Cancer enriched" "Detected in many" 19 "liver cancer: 1503.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 56 "Hep G2: 735.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027529, CAB033120, HPA074638" Supported Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 267000000000 73000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "CAB033120: AB_2103818, HPA027529: AB_10601322, HPA074638: " "unprognostic (1.26e-2)" "unprognostic (4.77e-3)" "unprognostic (6.33e-3)" "unprognostic (3.69e-3)" "unprognostic (2.18e-3)" "unprognostic (9.63e-2)" "unprognostic (7.57e-3)" "prognostic unfavorable (1.00e-6)" "unprognostic (1.75e-3)" "unprognostic (3.21e-1)" "unprognostic (1.14e-1)" 1.7 34.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 1.3 0.0 0.4 0.0 0.4 0.2 0.6 0.7 25.0 1.2 0.0 0.0 8.8 16556.3 50.2 0.1 0.0 0.0 1.4 15.8 0.0 0.4 6.3 0.0 0.4 0.0 0.0 0.4 0.3 0.4 0.5 0.6 0.0 0.0 9.1 8.7 3.0 0.1 0.3 0.4 0.0 0.0 0.5 0.6 0.1 0.0 13.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.2 0.0 1.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 3.5 0.4 735.3 0.2 8.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.3 0.0 0.6 0.0 0.0 0.3 6.4 0.0 0.0 0.6 0.0 0.0 5.3 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.5 0.1 0.1 1.7 0.0 3.6 0.2 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 19.2 214.4 0.0 31.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 633.4 2.5 0.0 0.0 0.0 0.0 0.1 0.0 21.9 4.3 0.0 0.1 9.2 0.0 157.7 0.0 48.5 0.2 0.5 0.0 0.1 11.4 1.1 202.4 10221.7 0.2 0.0 0.0 0.0 0.0 289.5 0.0 0.5 0.0 0.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 161.8 0.0 0.0 0.0 0.0 0.0 1.6 1.5 0.0 0.0 0.0 0.1 2.0 0.6 0.0 0.0 0.4 17.3 0.2 0.0 0.0 FGR "c-fgr, p55c-fgr, SRC2" ENSG00000000938 "FGR proto-oncogene, Src family tyrosine kinase" P09769 1 27612064-27635185 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 207.8;lung: 86.5;lymphoid tissue: 141.1" "Cell type enhanced" "Detected in many" "Kupffer cells: 182.2;Langerhans cells: 63.8;Macrophages: 155.9;monocytes: 159.7;NK-cells: 259.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Daudi: 86.0;U-266/70: 153.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002024 Enhanced Approved "Plasma membrane,Aggresome" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Aggresome "HPA002024: AB_1078503" "unprognostic (2.66e-2)" "unprognostic (1.51e-2)" "unprognostic (6.32e-2)" "unprognostic (9.74e-3)" "unprognostic (6.66e-3)" "unprognostic (6.71e-2)" "unprognostic (5.77e-2)" "unprognostic (1.25e-1)" "unprognostic (1.81e-2)" "unprognostic (7.45e-2)" "unprognostic (2.79e-2)" "unprognostic (1.10e-1)" "unprognostic (1.94e-2)" "unprognostic (6.26e-2)" "unprognostic (3.93e-2)" "unprognostic (2.30e-1)" "unprognostic (8.12e-3)" 25.0 6.8 12.8 62.2 11.9 207.8 16.0 11.9 19.1 7.6 11.5 6.0 3.9 8.1 1.7 5.2 15.6 12.7 8.7 11.4 12.3 7.5 10.8 86.5 27.5 13.6 12.7 2.9 5.8 1.6 2.7 7.9 14.5 7.2 4.0 0.7 6.6 2.4 3.2 4.5 10.1 16.3 12.5 141.1 5.9 2.5 17.2 8.4 7.4 6.5 20.0 17.8 7.3 12.6 0.0 0.0 0.3 0.0 0.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 86.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.0 0.0 1.7 29.3 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.3 0.0 0.0 3.8 5.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 153.1 2.1 6.5 0.0 19.5 0.0 30.8 381.4 229.4 189.5 469.1 11.3 54.0 15.8 89.1 196.1 84.0 8.0 78.4 272.9 264.5 405.2 9.0 1.2 494.1 12.8 11.9 11.9 19.1 11.4 12.3 13.6 12.7 14.5 12.5 17.2 12.6 8.6 6.4 20.0 0.0 24.9 2.8 0.6 0.2 0.0 0.0 0.4 0.6 1.6 1.5 5.7 1.8 0.0 0.5 55.2 0.0 0.0 0.0 0.3 0.1 0.2 14.9 0.0 7.4 0.2 0.2 0.7 2.7 1.5 0.1 13.3 0.1 6.8 1.9 56.8 0.0 0.1 0.0 0.0 182.2 63.8 0.7 0.3 155.9 1.8 6.5 159.7 0.1 259.5 1.0 0.4 0.0 1.2 0.0 4.2 0.4 0.0 0.7 1.5 0.0 0.0 0.7 0.6 0.2 0.5 0.5 1.1 1.0 28.0 0.0 0.0 2.5 FH ENSG00000091483 "Fumarate hydratase" P07954 1 241497603-241519755 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Tricarboxylic acid cycle" Lyase "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 276.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 173.5;Early spermatids: 226.0;Syncytiotrophoblasts: 166.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017785, HPA025770, HPA025948, HPA027341" Enhanced Supported Enhanced Mitochondria NA NA 1800000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB017785: , HPA025770: AB_10599603, HPA025948: AB_10602177, HPA027341: AB_10601222" "unprognostic (1.03e-2)" "unprognostic (3.82e-2)" "unprognostic (9.46e-3)" "unprognostic (2.18e-1)" "unprognostic (2.10e-1)" "unprognostic (2.07e-1)" "unprognostic (2.28e-2)" "unprognostic (1.55e-1)" "unprognostic (5.14e-2)" "unprognostic (1.85e-2)" "unprognostic (1.27e-2)" "unprognostic (1.09e-1)" "prognostic favorable (2.76e-7)" "unprognostic (1.05e-1)" "unprognostic (1.05e-1)" "unprognostic (4.41e-2)" "unprognostic (1.24e-2)" 43.4 75.2 30.4 31.0 33.3 31.4 37.3 33.5 42.0 28.9 43.9 66.8 68.2 36.9 26.1 51.1 27.9 23.7 179.0 33.9 33.1 101.8 276.4 26.4 30.0 31.8 31.0 24.9 38.1 95.0 31.1 32.1 32.1 33.5 69.0 58.8 42.0 38.4 213.4 40.3 59.1 42.0 32.4 30.1 53.6 44.4 32.7 31.3 34.6 229.3 40.4 37.5 33.7 33.0 129.2 105.6 97.9 89.0 93.9 110.0 154.9 155.7 121.1 171.6 107.1 152.2 78.0 81.1 100.3 119.9 75.0 178.4 151.7 115.8 148.4 93.5 48.9 76.3 102.2 131.4 84.1 180.2 66.7 80.2 70.7 96.6 108.0 60.2 107.2 175.8 236.3 101.7 126.9 64.3 156.6 120.1 104.5 186.2 223.6 127.4 107.2 365.7 167.4 107.6 125.4 108.4 131.1 153.3 104.0 67.2 117.1 120.9 106.5 76.6 98.9 137.0 264.0 90.3 103.7 97.3 85.7 203.5 112.6 11.9 22.8 4.9 16.1 33.3 21.0 27.2 18.8 15.1 46.7 25.1 22.3 21.1 1.3 18.3 29.1 23.1 23.8 16.7 30.4 33.3 33.5 42.0 33.9 33.1 31.8 31.0 32.1 32.4 32.7 33.0 17.1 38.5 30.2 9.4 25.0 20.0 24.6 69.5 17.1 24.7 19.9 17.5 173.5 35.8 40.0 23.9 14.6 101.6 13.7 44.0 78.2 60.4 226.0 25.4 23.5 18.6 18.0 37.7 12.7 45.0 58.7 25.5 26.5 25.4 19.0 24.9 13.6 80.4 50.7 35.3 14.9 40.6 48.8 18.5 14.4 37.4 23.9 23.9 24.9 8.4 27.9 35.0 10.3 8.0 14.4 29.4 35.7 26.7 41.3 19.0 66.1 86.0 29.2 39.1 39.5 27.7 67.9 84.7 47.1 32.1 18.6 166.1 14.9 48.4 74.2 22.8 FILIP1L "DOC-1, GIP130" ENSG00000168386 "Filamin A interacting protein 1 like" Q4L180 3 99830141-100114513 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 210.1;Early spermatids: 376.7;Sertoli cells: 256.4;Skeletal myocytes: 184.2;Smooth muscle cells: 351.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.9" "Group enriched" "Detected in many" 4 "dendritic cells: 2.1;monocytes: 2.9" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 84.2;HDLM-2: 79.9;TIME: 145.8" "Region enriched" "Detected in many" 7 "olfactory bulb: 18.0" "Low region specificity" "Detected in all" HPA043133 Approved Approved "Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA043133: AB_10793991" "unprognostic (9.14e-2)" "unprognostic (2.16e-1)" "unprognostic (7.73e-2)" "unprognostic (5.25e-2)" "unprognostic (6.68e-2)" "unprognostic (1.06e-2)" "unprognostic (4.40e-2)" "unprognostic (1.29e-1)" "unprognostic (2.08e-2)" "unprognostic (2.18e-1)" "unprognostic (1.02e-1)" "unprognostic (3.32e-1)" "prognostic unfavorable (9.40e-4)" "unprognostic (2.46e-2)" "unprognostic (9.44e-2)" "unprognostic (5.30e-2)" "unprognostic (1.82e-3)" 77.1 21.7 4.9 52.4 6.3 0.8 32.6 4.8 6.6 63.8 4.0 57.7 28.4 117.6 23.8 56.0 31.2 90.9 54.8 6.2 4.4 24.0 28.1 30.7 30.1 9.6 4.2 76.4 35.5 17.5 3.9 43.9 9.7 67.9 29.8 4.7 9.3 54.3 140.4 16.8 41.2 151.7 3.7 42.9 46.7 22.0 3.6 11.9 20.1 161.5 22.3 101.5 21.9 4.0 59.0 0.0 22.3 0.1 35.8 30.2 2.0 29.4 58.8 50.2 56.5 17.8 0.2 0.2 5.0 84.2 13.2 7.1 0.0 14.4 59.0 79.9 0.6 4.8 0.2 23.3 17.8 1.4 0.0 24.2 5.1 5.6 0.0 32.0 22.8 0.0 3.8 0.5 7.7 0.1 5.2 1.2 1.3 3.1 0.0 0.1 26.1 0.7 33.5 1.0 2.0 3.7 0.4 0.4 0.1 11.7 0.0 10.5 145.8 8.8 0.2 1.9 15.5 4.2 0.2 0.3 6.5 0.4 0.0 0.2 0.4 0.0 0.1 1.0 0.0 0.6 0.1 0.1 2.1 0.6 0.0 0.1 0.2 0.4 2.9 0.4 0.1 0.3 4.9 6.3 4.8 6.6 6.2 4.4 9.6 4.2 9.7 3.7 3.6 4.0 92.9 16.0 23.1 9.4 4.1 27.8 56.7 7.9 2.2 11.8 12.3 6.5 145.7 35.8 2.3 5.5 8.4 1.1 1.8 2.1 1.9 210.1 376.7 2.3 60.5 77.2 3.0 0.0 42.0 109.3 0.7 145.2 21.9 2.4 34.8 16.3 41.0 0.7 3.2 106.0 25.8 5.7 6.1 36.3 98.9 180.2 83.0 86.1 17.8 25.3 17.7 0.9 0.0 22.1 21.6 43.7 0.2 104.2 3.0 5.1 5.4 2.6 1.9 6.0 256.4 184.2 351.9 40.1 2.5 1.5 22.7 3.1 8.8 41.8 3.2 3.5 FLT1 "FLT, VEGFR1" ENSG00000102755 "Fms related receptor tyrosine kinase 1" P17948 13 28300346-28495145 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "placenta: 432.4" "Cell type enhanced" "Detected in many" "Adipocytes: 411.6;Endothelial cells: 263.1;Extravillous trophoblasts: 815.4;Hepatic stellate cells: 234.9;Microglial cells: 433.8;Syncytiotrophoblasts: 1127.1" "Cancer enhanced" "Detected in all" "renal cancer: 28.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 71.8;BJ hTERT+: 57.2;HMC-1: 349.2;HUVEC TERT2: 64.9;WM-115: 127.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011740, HPA014290, CAB068189, CAB068190" Enhanced Supported "Plasma membrane,Actin filaments" "Secreted to blood" NA NA 876000 87000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Actin filaments" "CAB068189: AB_2665636, CAB068190: AB_2665637, HPA011740: AB_1858737, HPA014290: AB_1858738" "unprognostic (3.33e-2)" "unprognostic (3.52e-3)" "unprognostic (1.13e-3)" "unprognostic (5.02e-2)" "unprognostic (3.65e-1)" "unprognostic (5.03e-2)" "unprognostic (8.25e-2)" "unprognostic (2.27e-3)" "unprognostic (9.91e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (4.20e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" 47.6 9.6 37.6 9.1 36.2 1.1 31.2 37.0 43.0 16.4 24.6 9.4 7.5 17.2 3.7 5.9 11.7 16.6 46.0 33.3 39.8 34.9 18.2 25.8 5.3 44.6 40.0 4.4 12.7 30.5 9.0 432.4 50.1 13.9 6.1 52.5 7.0 11.0 19.9 5.9 9.3 17.4 33.4 18.6 10.9 17.4 59.6 3.6 48.9 38.8 5.7 14.0 9.5 38.7 0.1 0.0 0.0 0.6 0.6 0.9 0.3 71.8 57.2 25.8 14.9 0.0 0.2 0.1 0.1 9.6 0.0 0.3 6.7 0.0 45.4 0.0 2.0 0.2 0.1 0.0 0.1 0.0 349.2 0.6 0.0 0.1 1.0 0.1 64.9 6.1 1.7 0.3 0.0 0.3 4.5 3.7 37.5 0.0 0.1 2.9 0.0 0.1 0.1 0.1 8.1 0.6 0.0 0.1 0.2 44.4 0.3 0.2 6.3 0.2 1.2 0.1 0.1 2.1 1.0 0.2 0.4 0.3 127.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 37.6 36.2 37.0 43.0 33.3 39.8 44.6 40.0 50.1 33.4 59.6 38.7 411.6 0.0 6.0 2.0 4.7 4.1 0.7 0.2 3.4 17.8 1.2 1.5 26.5 2.8 2.9 0.0 4.2 197.2 1.4 0.1 1.9 0.6 157.2 0.5 1.5 263.1 0.0 0.0 0.9 0.0 815.4 32.1 0.5 2.1 1.3 0.1 234.9 6.9 30.8 1.7 14.5 0.0 0.0 12.5 23.6 173.8 18.6 15.3 0.0 433.8 0.0 153.2 0.0 9.5 2.0 0.0 0.0 48.5 4.1 1.3 0.0 0.1 1.8 9.7 92.1 11.4 30.1 14.6 4.6 1.0 4.8 1127.1 2.8 1.5 0.0 1.1 FMNL3 "DKFZp762B245, MGC45819, WBP3" ENSG00000161791 "Formin like 3" Q8IVF7 12 49636499-49708165 "Predicted intracellular proteins" Angiogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 35.8;Cone photoreceptor cells: 39.6;dendritic cells: 48.6;Microglial cells: 119.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 5.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 47.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002552, HPA023201" Uncertain Supported "Golgi apparatus,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Vesicles, Plasma membrane" Cytosol "HPA002552: AB_1078862, HPA023201: AB_1848575" "unprognostic (2.97e-1)" "unprognostic (2.77e-3)" "unprognostic (4.97e-3)" "unprognostic (7.19e-2)" "unprognostic (5.42e-2)" "unprognostic (2.33e-3)" "unprognostic (5.37e-3)" "unprognostic (1.52e-2)" "unprognostic (2.83e-1)" "unprognostic (1.54e-1)" "unprognostic (6.67e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (3.58e-5)" "unprognostic (1.04e-1)" "unprognostic (2.31e-1)" "unprognostic (2.03e-1)" "unprognostic (2.69e-2)" 12.2 5.7 13.7 20.5 13.2 5.2 10.6 13.0 11.2 9.6 3.0 8.0 5.7 11.2 19.2 4.5 6.9 11.1 12.6 11.0 12.6 9.3 2.7 17.4 23.5 21.7 14.6 16.1 3.2 3.6 4.1 14.0 18.2 6.0 5.6 2.7 4.6 4.4 5.6 4.4 10.2 11.5 17.7 13.4 6.6 10.1 20.4 20.1 13.4 6.7 28.3 8.6 6.3 20.4 8.6 2.5 18.4 6.1 5.0 20.1 0.2 10.4 21.0 13.8 12.1 9.7 2.3 18.2 19.5 12.4 15.2 0.4 9.5 4.3 12.6 16.2 3.6 20.1 2.9 0.5 8.8 4.0 25.1 12.7 0.7 21.7 9.1 41.2 37.1 9.0 4.6 13.0 20.5 6.3 16.6 6.0 6.0 0.9 5.5 7.9 23.0 2.8 13.1 1.3 3.0 8.6 6.0 0.8 11.8 9.3 1.5 5.9 47.2 34.2 11.8 0.6 18.2 6.7 0.4 9.8 21.3 12.4 14.7 3.0 0.1 0.8 0.8 0.4 0.4 0.2 0.3 0.5 0.2 1.1 0.4 0.5 0.0 0.6 0.3 5.1 0.1 0.5 13.7 13.2 13.0 11.2 11.0 12.6 21.7 14.6 18.2 17.7 20.4 20.4 35.8 3.2 3.4 6.8 17.5 1.7 0.7 0.4 2.2 11.3 1.3 2.3 3.3 0.0 1.4 1.8 39.6 2.1 48.6 0.1 0.0 0.3 2.0 0.7 2.6 29.7 0.0 1.7 16.0 0.6 0.8 7.1 1.5 2.0 27.8 5.4 15.7 0.8 11.1 3.3 6.5 0.8 0.0 6.9 9.0 4.6 3.7 17.7 5.4 119.0 22.9 0.5 16.5 27.6 5.5 0.8 0.1 6.4 1.8 0.8 0.0 0.2 0.2 2.0 13.1 15.5 10.3 5.9 7.5 0.4 1.4 2.5 13.6 2.6 0.1 0.4 FMOD SLRR2E ENSG00000122176 Fibromodulin Q06828 1 203340628-203351758 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 26.7;Fibroblasts: 52.5;Intestinal goblet cells: 80.2;Leydig cells: 28.0;Peritubular cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 10.6;CACO-2: 38.6;HHSteC: 11.8;HSkMC: 22.1;OE19: 45.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 71.7" "Secreted to extracellular matrix" NA NA 2600000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 21: OE19 - Mitochondria" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.48e-1)" "unprognostic (8.88e-2)" "unprognostic (9.35e-2)" "unprognostic (2.70e-2)" "unprognostic (1.60e-2)" "unprognostic (4.17e-3)" "unprognostic (1.86e-1)" "unprognostic (3.30e-1)" "unprognostic (5.25e-3)" "unprognostic (1.06e-2)" "unprognostic (1.65e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.40e-5)" "unprognostic (9.40e-3)" "unprognostic (3.58e-2)" "unprognostic (1.27e-3)" "prognostic unfavorable (2.67e-4)" 122.7 13.6 1.3 31.1 2.3 0.1 64.4 1.5 3.9 100.1 9.0 39.4 49.6 105.8 17.2 19.1 85.8 123.6 149.0 1.0 1.5 24.3 11.0 60.2 28.6 2.4 0.9 125.1 33.1 28.0 21.7 81.2 1.5 58.4 62.1 9.9 49.6 49.2 12.6 25.9 21.2 106.5 2.1 18.2 135.6 6.3 1.5 9.6 71.3 25.6 33.8 45.4 60.0 1.4 0.0 0.1 0.0 0.0 10.6 0.7 0.2 7.1 8.1 0.0 1.1 38.6 0.0 0.0 0.8 7.7 0.0 0.3 0.0 0.6 0.5 0.0 0.0 0.0 0.9 0.0 11.8 0.0 0.0 22.1 0.1 0.0 0.4 5.2 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.3 0.0 45.8 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 1.5 0.4 0.0 0.1 1.0 0.3 2.0 0.0 0.3 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.3 1.5 3.9 1.0 1.5 2.4 0.9 1.5 2.1 1.5 1.4 9.3 0.0 6.3 0.0 0.0 6.9 5.0 1.5 6.2 0.2 10.3 26.7 1.6 2.8 2.1 7.3 0.0 1.1 0.4 2.9 0.0 1.9 0.1 1.1 12.1 8.3 6.1 0.0 0.1 0.7 0.7 52.5 12.8 1.6 0.0 0.5 19.2 0.1 1.2 0.0 0.0 80.2 0.0 0.3 9.3 0.4 28.0 0.6 12.4 7.5 0.6 11.9 0.0 0.0 0.0 1.5 2.2 28.6 0.0 11.7 0.7 0.2 0.7 1.0 6.6 1.3 15.5 0.0 0.3 0.6 4.3 3.1 1.2 2.0 8.6 1.6 FNDC1 "bA243O10.1, dJ322A24.1, FNDC2, KIAA1866" ENSG00000164694 "Fibronectin type III domain containing 1" Q4ZHG4 6 159169400-159272108 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 14.2;thyroid gland: 20.3" "Group enriched" "Detected in some" 4 "Fibroblasts: 28.7;Smooth muscle cells: 11.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 32.5" "Group enriched" "Detected in many" 6 "cerebral cortex: 5.4;hippocampal formation: 8.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.0;fHDF/TERT166: 2.9;SuSa: 3.1" "Region enhanced" "Detected in many" "olfactory bulb: 7.0" "Region enhanced" "Detected in many" "spinal cord: 10.3" "HPA030962, HPA030963" Approved Approved "Nuclear speckles" "Secreted to extracellular matrix" NA NA 14000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" "HPA030962: AB_10696212, HPA030963: AB_2673676" "unprognostic (4.59e-2)" "unprognostic (9.17e-3)" "unprognostic (7.62e-2)" "prognostic favorable (6.10e-5)" "unprognostic (4.57e-1)" "unprognostic (2.11e-1)" "unprognostic (5.52e-2)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "unprognostic (1.08e-1)" "unprognostic (4.18e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (1.93e-6)" "unprognostic (6.49e-3)" "unprognostic (1.12e-1)" "unprognostic (3.10e-1)" "unprognostic (1.76e-3)" 5.4 0.5 0.5 1.9 0.3 0.0 2.1 0.1 5.4 6.5 0.2 12.9 2.5 2.2 0.0 1.1 0.6 14.2 3.9 8.7 0.3 0.6 0.7 1.6 2.8 0.1 1.0 1.2 1.1 0.3 0.2 0.9 0.0 0.4 1.8 0.1 0.9 0.8 2.1 0.9 4.2 11.7 0.3 0.5 0.4 0.4 0.4 0.1 20.3 9.6 2.4 1.0 1.6 1.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.0 2.9 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 3.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.1 5.4 8.7 0.3 0.1 1.0 0.0 0.3 0.4 1.2 2.6 0.0 0.6 0.0 0.0 3.2 0.0 0.0 0.0 0.3 0.1 0.5 2.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.3 0.4 4.7 0.7 0.0 0.0 0.2 0.0 0.2 28.7 0.0 0.3 0.0 0.1 1.4 0.0 0.2 0.0 1.7 0.0 0.0 0.0 3.1 0.0 0.3 0.2 1.8 2.8 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 3.0 11.5 1.1 1.4 0.0 1.4 0.1 0.5 0.1 0.0 0.0 FOXA1 HNF3A ENSG00000129514 "Forkhead box A1" P55317 14 37589552-37596059 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 74.7;stomach 1: 28.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 113.8;Basal squamous epithelial cells: 76.8;Breast glandular cells: 87.9;Enteroendocrine cells: 84.6;Prostatic glandular cells: 89.8;Respiratory ciliated cells: 66.7;Urothelial cells: 154.5" "Group enriched" "Detected in many" 5 "breast cancer: 80.0;prostate cancer: 127.0" "Region enriched" "Detected in single" 5 "midbrain: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 48.9;MCF7: 105.3;PC-3: 69.5;RT4: 96.7;SK-BR-3: 97.0;T-47d: 135.9" "Region enhanced" "Detected in some" "midbrain: 1.1" "Region enriched" "Detected in single" 6 "midbrain: 5.4" "CAB011595, HPA050505" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "Nucleoli fibrillar center" "CAB011595: AB_2104842, HPA050505: AB_2681148" "unprognostic (1.61e-1)" "unprognostic (8.80e-2)" "unprognostic (1.12e-1)" "unprognostic (4.65e-1)" "unprognostic (2.58e-1)" "unprognostic (1.51e-1)" "unprognostic (1.74e-1)" "unprognostic (1.78e-1)" "unprognostic (1.71e-1)" "unprognostic (3.01e-1)" "unprognostic (1.54e-2)" "unprognostic (6.30e-2)" "unprognostic (0.00e+0)" "unprognostic (3.67e-1)" "unprognostic (2.58e-1)" "unprognostic (1.69e-2)" "prognostic favorable (1.00e-4)" 0.2 0.1 0.0 1.6 0.0 0.0 22.3 0.0 0.0 1.5 0.0 12.4 8.4 0.1 0.6 11.9 2.4 2.3 0.0 0.0 0.3 0.1 26.9 7.5 0.0 0.1 3.5 0.0 0.5 0.0 0.7 0.0 0.2 74.7 10.4 0.0 19.3 0.3 0.0 1.3 4.8 0.2 0.2 0.0 28.0 0.4 0.7 0.0 0.0 0.0 2.3 20.5 4.4 0.0 4.9 4.4 0.0 2.8 0.0 0.0 0.5 0.0 0.4 0.0 0.0 21.3 2.7 0.0 1.4 0.0 0.1 23.4 13.2 3.3 0.1 0.0 23.4 0.0 4.1 48.9 0.0 0.0 0.2 0.0 0.7 0.0 0.4 1.9 0.0 0.4 0.9 0.0 0.0 105.3 0.1 0.3 0.0 32.0 69.5 0.0 1.1 0.4 9.9 96.7 11.8 0.0 4.8 97.0 0.0 0.0 135.9 0.4 0.0 0.9 0.1 0.4 3.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 3.5 0.2 0.2 0.7 0.0 0.3 28.9 43.5 0.0 0.1 1.0 113.8 47.8 76.8 0.0 87.9 34.8 1.3 30.0 52.3 3.7 0.0 0.0 0.5 27.5 0.0 1.5 0.4 2.7 0.2 1.2 84.6 0.0 0.0 2.4 0.0 1.0 35.7 4.4 2.5 0.0 1.1 31.7 0.0 0.0 0.0 34.9 42.7 0.9 0.3 0.9 0.0 0.7 3.6 0.0 1.0 0.0 0.0 0.0 0.0 4.3 27.2 0.0 1.2 89.8 4.9 0.0 66.7 0.0 0.0 0.0 2.3 0.9 1.2 62.9 0.1 0.0 1.4 0.1 27.9 154.5 FOXF1 "FKHL5, FREAC1" ENSG00000103241 "Forkhead box F1" Q12946 16 86510527-86515422 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 61.2;urinary bladder: 49.9" "Group enriched" "Detected in some" 4 "Endothelial cells: 17.1;Fibroblasts: 46.3;Smooth muscle cells: 18.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BJ: 12.8;BJ hTERT+: 27.9;HHSteC: 26.5;U-2197: 11.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA028886 Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "HPA028886: AB_10601652" "unprognostic (7.91e-2)" "unprognostic (3.02e-3)" "unprognostic (1.23e-1)" "unprognostic (4.38e-2)" "unprognostic (1.84e-2)" "unprognostic (2.62e-3)" "unprognostic (2.37e-2)" "unprognostic (1.08e-1)" "unprognostic (8.22e-2)" "unprognostic (6.07e-3)" "unprognostic (1.06e-1)" "unprognostic (1.91e-2)" "unprognostic (1.29e-2)" "unprognostic (4.89e-2)" "unprognostic (4.20e-2)" "unprognostic (7.11e-2)" "unprognostic (2.44e-1)" 3.6 0.2 6.0 10.2 5.3 0.0 1.2 4.8 5.4 16.2 2.9 61.2 8.9 2.7 1.1 10.1 1.8 15.0 0.8 4.5 4.8 2.1 3.2 34.1 3.2 5.9 5.2 0.7 1.3 1.1 0.4 23.1 6.0 25.8 10.8 0.2 1.2 5.4 0.2 0.3 21.2 11.7 5.1 0.6 26.3 0.7 7.0 0.1 5.4 1.4 1.5 49.9 11.8 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.8 27.9 3.8 1.3 0.0 0.1 0.0 0.0 1.2 2.6 0.0 2.2 0.0 3.3 0.0 1.5 0.0 2.1 0.0 26.5 0.0 2.3 2.8 0.0 4.5 0.5 0.4 4.7 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 4.4 0.8 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.6 0.1 0.0 0.0 0.0 1.9 11.9 0.0 0.0 0.0 0.0 2.5 0.1 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 5.3 4.8 5.4 4.5 4.8 5.9 5.2 6.0 5.1 7.0 5.1 2.0 0.0 0.6 0.0 0.0 0.3 0.3 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.4 0.3 17.1 0.0 0.0 0.0 0.0 0.4 46.3 1.1 0.2 0.0 0.0 2.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.3 0.2 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 1.0 0.0 0.0 0.0 0.4 0.0 0.1 18.7 0.0 1.3 0.6 0.3 1.2 0.1 0.1 0.0 0.6 FPR2 "ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH2, FPRL1, HM63, LXA4R" ENSG00000171049 "Formyl peptide receptor 2" P25090 19 51752026-51770531 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 56.1" "Cell type enhanced" "Detected in some" "Early spermatids: 9.0;Hofbauer cells: 12.7;Kupffer cells: 18.8;Late spermatids: 26.8;Macrophages: 61.3;monocytes: 23.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 10 "neutrophil: 1187.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 1187.9" "Cell line enriched" "Detected in some" 20 "U-937: 32.7" "Not detected" "Not detected" HPA029154 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA029154: AB_10602133" "unprognostic (3.11e-1)" "unprognostic (5.20e-2)" "unprognostic (1.71e-2)" "unprognostic (1.44e-1)" "unprognostic (1.07e-1)" "unprognostic (1.65e-1)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (1.00e-1)" "unprognostic (1.23e-1)" "unprognostic (5.04e-2)" "unprognostic (3.90e-4)" "unprognostic (3.41e-5)" "unprognostic (1.08e-2)" "unprognostic (4.69e-2)" "unprognostic (5.10e-2)" "unprognostic (1.90e-1)" 13.6 1.2 0.3 56.1 0.6 16.6 0.6 0.3 2.6 0.5 0.9 0.8 1.0 0.5 0.1 1.8 1.8 5.9 0.9 0.3 0.3 0.4 4.9 9.4 1.9 0.6 0.5 1.5 2.3 0.3 0.2 7.6 0.9 0.4 0.5 0.1 0.5 0.3 0.3 0.4 1.3 6.7 0.3 17.2 0.7 2.4 1.2 1.6 0.7 4.2 0.8 15.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.8 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.9 32.7 0.0 3.6 122.0 5.8 0.2 122.7 0.7 0.1 0.2 0.2 16.6 0.2 0.1 0.2 1187.9 0.2 85.0 3.3 0.1 46.0 0.3 0.6 0.3 2.6 0.3 0.3 0.6 0.5 0.9 0.3 1.2 0.5 0.0 0.0 5.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 9.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.0 5.1 0.0 0.4 0.4 12.7 0.0 0.0 0.0 0.0 18.8 0.8 26.8 0.0 61.3 0.0 0.0 23.3 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.4 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 FPR3 "FMLPY, FPRH1, FPRL2, RMLP-R-I" ENSG00000187474 "Formyl peptide receptor 3" P25089 19 51795157-51826190 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 28.2" "Group enriched" "Detected in some" 15 "Hofbauer cells: 56.5;Kupffer cells: 97.4;Langerhans cells: 223.6;Macrophages: 66.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 20 "classical monocyte: 2.3;intermediate monocyte: 6.7;myeloid DC: 2.4" "Group enriched" "Detected in many" 44 "dendritic cells: 2.4;monocytes: 6.7" "Group enriched" "Detected in some" 5 "HEL: 10.0;hTERT-RPE1: 2.7" "Not detected" "Not detected" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.77e-2)" "unprognostic (1.54e-1)" "unprognostic (1.79e-2)" "unprognostic (1.29e-1)" "unprognostic (1.15e-1)" "unprognostic (1.84e-1)" "unprognostic (8.41e-2)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" "unprognostic (7.14e-2)" "unprognostic (3.17e-1)" "unprognostic (9.37e-2)" "unprognostic (1.02e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (9.13e-4)" "unprognostic (1.96e-1)" "unprognostic (4.28e-2)" 10.6 12.1 0.6 23.9 1.1 0.4 5.3 0.5 2.4 5.5 2.2 12.6 11.2 3.7 1.5 5.7 2.0 18.8 3.8 0.6 0.7 3.2 21.3 28.2 13.9 3.1 1.0 1.7 2.3 2.2 0.9 5.6 2.8 2.5 18.2 0.3 2.4 2.9 0.9 2.7 14.4 8.9 1.2 16.3 7.1 2.7 6.0 8.1 2.2 2.0 11.0 17.4 1.2 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.3 0.0 0.0 6.7 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.6 1.1 0.5 2.4 0.6 0.7 3.1 1.0 2.8 1.2 6.0 3.9 0.5 0.0 1.7 0.3 2.7 5.6 0.0 0.0 0.0 0.1 0.1 0.5 0.2 0.0 2.5 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.4 0.8 0.0 0.0 0.0 0.0 1.1 1.5 56.5 0.0 0.2 0.0 0.0 97.4 223.6 0.2 0.3 66.6 7.2 1.0 3.7 0.0 0.0 0.0 0.7 0.0 0.0 1.2 0.4 0.1 0.0 0.0 1.5 0.1 0.0 0.3 0.5 0.0 0.1 0.4 4.5 0.8 0.6 0.0 0.0 0.1 FRAS1 "FLJ14927, FLJ22031, KIAA1500" ENSG00000138759 "Fraser extracellular matrix complex subunit 1" Q86XX4 4 78057323-78544269 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.8;thyroid gland: 12.0" "Group enriched" "Detected in many" 9 "Excitatory neurons: 204.9;Inhibitory neurons: 377.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 35.9;Hep G2: 21.9;RH-30: 20.1;SiHa: 21.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051601 Approved "Intracellular and membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA051601: AB_2681547" "unprognostic (1.33e-2)" "unprognostic (1.04e-2)" "unprognostic (9.37e-2)" "unprognostic (8.91e-2)" "unprognostic (2.97e-1)" "unprognostic (2.04e-1)" "unprognostic (1.45e-3)" "unprognostic (2.02e-2)" "unprognostic (1.07e-1)" "unprognostic (2.69e-2)" "unprognostic (2.09e-2)" "unprognostic (4.02e-2)" "prognostic favorable (4.69e-4)" "unprognostic (2.56e-1)" "unprognostic (1.10e-1)" "unprognostic (4.78e-3)" "unprognostic (6.09e-2)" 2.0 0.6 3.4 0.5 5.8 0.0 0.7 0.0 7.9 2.1 4.0 3.5 0.3 2.0 1.9 1.7 1.0 0.9 1.5 3.5 3.3 7.4 0.3 3.4 0.1 3.1 3.3 0.2 5.4 0.6 2.4 5.8 3.0 2.3 1.3 2.2 1.0 0.7 2.7 1.3 1.0 1.4 0.6 0.7 0.9 0.6 13.8 2.6 12.0 2.2 0.2 0.5 1.4 4.9 4.6 6.9 2.7 0.0 7.0 2.9 4.8 1.1 4.1 0.6 0.4 5.4 9.8 0.0 8.2 35.9 0.0 1.3 3.8 2.1 0.1 0.0 3.8 4.2 8.5 21.9 0.8 0.0 0.0 14.1 2.3 0.0 5.2 5.4 0.1 0.3 0.0 0.0 4.1 0.2 0.1 0.0 8.6 3.6 1.3 0.0 20.1 0.0 8.7 9.9 5.0 9.7 21.6 6.7 1.3 12.3 0.0 0.0 0.0 0.0 4.5 2.9 1.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 5.8 0.0 7.9 3.5 3.3 3.1 3.3 3.0 0.6 13.8 4.9 0.5 32.1 0.0 9.1 0.1 1.9 2.2 2.5 10.2 10.8 0.8 1.8 7.3 22.8 9.2 29.5 0.0 28.0 0.0 0.8 3.9 7.6 2.1 5.5 1.0 2.0 1.2 0.0 204.9 1.7 1.4 5.3 4.1 13.5 0.0 0.1 1.1 0.2 4.4 0.0 377.7 1.0 0.0 0.0 0.7 2.8 0.6 0.4 1.8 20.6 0.0 0.6 0.0 10.1 5.5 2.7 2.5 0.0 0.0 1.8 1.4 4.3 2.5 2.7 0.0 1.5 3.4 0.8 1.2 10.4 1.3 15.6 0.1 2.8 2.4 0.4 FREM1 "C9orf143, C9orf145, C9orf154, DKFZp686M16108, FLJ25461, TILRR" ENSG00000164946 "FRAS1 related extracellular matrix 1" Q5H8C1 9 14737152-14910995 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Developmental protein" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 36.4" "Group enriched" "Detected in many" 7 "Early spermatids: 73.7;Inhibitory neurons: 126.1;Late spermatids: 144.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "HEL: 163.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA 58000 "Cluster 68: Epididymis - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.13e-5)" "unprognostic (2.59e-3)" "unprognostic (2.89e-1)" "unprognostic (1.13e-1)" "unprognostic (1.97e-1)" "unprognostic (6.27e-3)" "unprognostic (2.50e-1)" "unprognostic (4.66e-3)" "unprognostic (4.43e-1)" "unprognostic (1.31e-1)" "unprognostic (3.62e-2)" "unprognostic (6.23e-2)" "unprognostic (8.95e-13)" "unprognostic (2.28e-3)" "unprognostic (8.53e-2)" "unprognostic (3.41e-2)" "unprognostic (2.86e-1)" 5.3 2.5 0.9 0.8 1.1 0.2 4.8 4.2 1.3 5.0 2.0 6.4 2.1 19.7 36.4 1.0 4.1 3.7 6.4 1.1 1.3 17.0 0.9 2.4 0.0 2.0 1.3 1.4 6.6 5.0 1.0 5.5 1.2 1.1 1.7 1.3 0.8 3.4 0.9 3.3 5.4 14.2 3.0 0.4 1.0 4.2 1.2 1.2 0.7 0.8 0.5 2.1 2.3 3.8 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 163.8 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.4 3.7 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 4.2 1.3 1.1 1.3 2.0 1.3 1.2 3.0 1.2 3.8 0.4 0.0 0.6 13.1 0.3 1.3 0.2 0.0 0.6 2.0 0.1 0.1 2.9 2.8 0.0 1.8 0.0 0.5 0.0 0.2 0.0 0.3 73.7 1.5 7.7 0.4 0.0 3.0 16.2 0.0 0.3 11.2 0.5 1.3 5.1 0.2 3.9 0.0 0.5 0.0 126.1 2.4 0.0 0.6 1.2 144.7 0.6 0.1 0.0 6.5 0.6 4.0 0.0 7.1 4.3 0.2 0.0 1.5 0.0 0.1 13.0 1.3 0.0 0.1 0.0 0.6 2.8 0.8 0.9 0.0 1.1 0.3 0.1 6.1 4.7 0.1 FUCA1 ENSG00000179163 "Alpha-L-fucosidase 1" P04066 1 23845077-23868290 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 181.7;Distal enterocytes: 226.6;Paneth cells: 221.0;Proximal enterocytes: 210.9;Syncytiotrophoblasts: 200.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 165.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046542, HPA056371" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 60000000 "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA046542: AB_2679691, HPA056371: AB_2683108" "unprognostic (6.94e-3)" "unprognostic (6.53e-2)" "unprognostic (2.68e-3)" "prognostic favorable (2.45e-4)" "unprognostic (5.64e-3)" "unprognostic (2.59e-3)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (4.99e-1)" "unprognostic (2.18e-2)" "unprognostic (2.05e-1)" "unprognostic (4.23e-2)" "prognostic favorable (5.70e-13)" "unprognostic (3.75e-2)" "unprognostic (4.35e-2)" "unprognostic (1.54e-2)" "unprognostic (2.13e-3)" 34.2 34.4 8.3 49.8 8.2 7.7 26.3 8.3 11.2 54.5 23.8 124.2 90.3 20.7 113.0 17.0 51.1 46.6 20.6 8.3 10.5 78.2 104.8 55.1 168.2 9.5 8.8 23.8 23.9 56.9 17.6 72.6 9.6 50.2 140.7 5.7 40.8 60.4 15.8 14.9 81.3 26.7 9.3 71.8 63.9 27.7 10.8 26.8 70.6 17.7 94.1 74.9 13.2 12.8 15.9 10.6 2.2 31.9 4.2 0.3 11.0 16.6 34.4 17.1 31.6 14.5 165.1 23.9 40.9 21.3 18.8 9.4 15.3 35.4 22.4 16.9 25.6 19.7 9.2 32.7 14.2 2.0 62.7 15.3 19.7 6.2 8.1 55.2 6.9 13.3 9.3 0.5 20.6 17.5 5.0 17.7 5.4 48.1 16.9 26.9 0.2 26.2 63.5 40.5 10.9 10.6 47.9 18.5 26.2 17.9 13.6 7.8 1.8 5.8 9.0 38.9 5.6 28.5 31.0 8.5 14.5 58.9 9.5 54.8 100.4 51.9 27.2 99.9 23.1 23.8 19.5 22.9 44.0 14.1 18.9 22.0 12.8 44.6 91.1 25.4 21.4 64.8 8.3 8.2 8.3 11.2 8.3 10.5 9.5 8.8 9.6 9.3 10.8 12.8 12.9 25.6 28.6 4.2 10.5 3.6 27.4 99.3 6.8 4.4 22.2 10.4 5.6 40.0 77.8 84.6 0.0 181.7 13.9 226.6 15.6 64.1 61.0 31.5 2.8 11.6 10.8 20.6 5.8 50.3 24.2 16.7 33.1 13.3 8.2 11.1 25.7 42.7 156.4 0.0 6.3 44.4 44.7 121.0 13.5 24.4 23.3 85.4 8.8 2.8 29.6 13.0 10.3 4.0 4.7 34.9 221.0 19.5 8.7 23.6 210.9 40.2 53.7 5.0 6.6 16.7 13.2 109.0 24.8 8.5 2.8 200.6 11.2 34.6 79.5 40.3 FUT1 "H, HSC" ENSG00000174951 "Fucosyltransferase 1 (H blood group)" P19526 19 48748011-48755390 "Blood group antigen proteins, Enzymes, Metabolic proteins, Predicted membrane proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 27.5" "Cell type enhanced" "Detected in many" "Adipocytes: 13.8;Endothelial cells: 8.5;Langerhans cells: 41.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 9.3;HEL: 11.5;RT4: 11.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA 15000 "Cluster 11: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.90e-2)" "unprognostic (3.09e-2)" "unprognostic (8.05e-3)" "unprognostic (4.65e-3)" "unprognostic (2.92e-3)" "unprognostic (8.73e-2)" "unprognostic (2.58e-2)" "unprognostic (3.34e-2)" "unprognostic (2.36e-1)" "unprognostic (1.38e-1)" "unprognostic (4.19e-2)" "unprognostic (1.29e-1)" "prognostic favorable (3.99e-4)" "unprognostic (1.33e-1)" "unprognostic (3.22e-2)" "unprognostic (8.67e-3)" "unprognostic (3.98e-2)" 3.8 1.6 2.3 0.6 3.5 2.9 3.1 5.2 3.3 1.2 1.0 0.7 1.9 0.9 0.9 2.8 2.0 1.0 3.8 3.1 1.5 4.1 1.0 10.6 0.7 1.6 1.6 0.3 27.5 3.3 2.7 4.2 1.7 1.4 0.5 0.3 1.4 1.0 1.7 1.6 0.6 0.9 1.3 5.4 13.6 1.6 2.0 0.7 1.9 2.9 1.4 1.3 1.4 1.8 3.8 0.1 0.2 0.2 0.0 0.0 1.8 0.2 0.1 0.2 0.2 9.3 5.4 0.4 0.4 0.3 0.8 6.2 1.9 5.8 0.2 0.1 0.9 11.5 0.4 0.2 2.6 0.4 4.9 0.0 9.1 0.4 4.1 0.1 4.1 2.0 0.6 1.8 0.0 4.4 0.2 7.3 1.1 7.5 0.5 0.3 0.0 1.9 0.3 11.2 8.5 0.5 0.5 8.0 0.2 0.4 5.2 0.3 4.0 0.4 2.6 0.2 0.4 1.5 4.3 1.1 0.1 0.3 0.4 1.3 0.2 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.1 0.1 0.5 0.3 0.0 0.2 0.0 0.0 2.3 3.5 5.2 3.3 3.1 1.5 1.6 1.6 1.7 1.3 2.0 1.8 13.8 3.2 1.7 0.0 0.0 2.5 0.7 4.1 1.2 0.4 1.2 0.9 1.1 2.8 2.3 0.0 2.1 0.4 0.0 0.1 1.9 1.7 0.0 1.3 0.3 8.5 1.2 6.5 1.3 2.4 0.3 0.8 4.1 3.4 1.3 0.0 6.8 0.0 0.3 0.0 0.4 1.2 2.0 0.8 41.9 0.1 0.9 1.9 5.4 1.0 0.0 0.0 0.0 0.0 0.1 3.6 0.0 0.0 0.1 0.9 0.1 0.0 0.9 0.2 0.0 0.6 0.9 0.1 0.1 2.4 1.7 0.4 0.3 0.0 0.1 0.6 FXYD2 "ATP1G1, HOMG2, MGC12372" ENSG00000137731 "FXYD domain containing ion transport regulator 2" P54710 11 117800844-117828698 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Disease variant, FDA approved drug targets, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 3645.4" "Group enriched" "Detected in many" 5 "Cholangiocytes: 1595.6;Distal tubular cells: 2952.4;Ductal cells: 892.8;Proximal tubular cells: 3423.7" "Cancer enriched" "Detected in some" 8 "renal cancer: 49.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "memory CD8 T-cell: 14.8;naive CD4 T-cell: 5.1;naive CD8 T-cell: 4.3;NK-cell: 9.6;plasmacytoid DC: 3.8" "Group enriched" "Detected in many" 7 "dendritic cells: 3.8;NK-cells: 9.6;T-cells: 14.8" "Group enriched" "Detected in some" 25 "MOLT-4: 2255.4;RPTEC TERT1: 4711.9" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 5 "spinal cord: 27.7" "HPA064218, HPA068838" Supported Approved Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA064218: AB_2685214, HPA068838: AB_2686047" "unprognostic (4.11e-4)" "unprognostic (1.14e-2)" "unprognostic (1.63e-1)" "unprognostic (1.36e-3)" "unprognostic (1.09e-3)" "unprognostic (2.30e-2)" "unprognostic (3.65e-2)" "unprognostic (4.62e-1)" "unprognostic (4.01e-2)" "unprognostic (4.91e-2)" "unprognostic (1.24e-2)" "unprognostic (2.64e-1)" "prognostic favorable (3.23e-9)" "unprognostic (3.22e-3)" "unprognostic (4.38e-2)" "unprognostic (4.62e-1)" "unprognostic (3.00e-2)" 2.0 0.9 0.7 1.4 0.6 3.3 1.2 1.4 1.7 1.0 0.0 2.1 1.4 1.5 1.2 0.8 1.8 353.1 1.2 0.8 0.0 3645.4 23.8 4.4 8.9 0.0 0.1 2.4 612.6 0.2 1.6 0.8 0.0 1.7 0.8 1.1 835.6 0.7 0.3 1.0 1.6 2.2 0.0 3.1 2.8 0.6 0.0 74.8 1.0 0.6 4.5 1.8 0.9 0.4 0.0 118.6 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.4 3.5 0.0 0.2 0.4 0.2 0.0 0.3 0.2 0.0 0.1 0.2 83.6 0.1 0.2 0.7 0.0 0.0 0.0 0.0 0.0 1.9 140.3 0.0 0.0 0.2 0.3 2255.4 0.0 1.2 0.0 0.0 0.6 0.0 4.6 4711.9 0.0 1.9 0.0 0.0 2.9 0.2 0.2 0.8 0.3 0.8 0.0 1.3 0.5 0.0 1.0 0.3 0.2 0.1 0.2 0.0 0.0 1.2 0.0 1.0 0.0 1.0 0.2 1.8 14.8 0.2 0.3 5.1 4.3 0.0 9.6 0.0 3.8 1.7 2.1 0.7 0.6 1.4 1.7 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.4 1.0 0.0 0.6 0.0 33.6 1.1 0.1 0.8 0.6 0.2 0.1 0.5 1.2 1595.6 0.1 435.9 0.0 0.1 0.7 0.0 2952.4 892.8 21.8 1.6 4.1 2.2 15.1 2.7 0.0 10.0 0.1 3.5 0.5 41.3 0.0 0.6 4.2 3.9 3.6 0.0 0.0 0.3 16.2 4.5 4.1 25.9 9.3 24.8 0.0 0.0 8.8 0.5 1.0 0.0 0.0 23.2 0.0 7.5 0.4 0.2 0.0 3423.7 0.1 3.3 6.6 1.6 3.8 0.3 0.3 0.2 0.9 0.3 27.7 1.2 0.1 0.0 FXYD5 OIT2 ENSG00000089327 "FXYD domain containing ion transport regulator 5" Q96DB9 19 35154730-35169881 "Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 462.9;Hofbauer cells: 430.3;Langerhans cells: 492.1;Pancreatic endocrine cells: 585.0;T-cells: 459.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010817 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum" "HPA010817: AB_1849214" "unprognostic (3.97e-3)" "unprognostic (5.49e-2)" "unprognostic (6.37e-3)" "unprognostic (3.01e-1)" "unprognostic (2.50e-3)" "unprognostic (4.39e-3)" "unprognostic (4.68e-2)" "unprognostic (1.56e-3)" "unprognostic (3.85e-1)" "unprognostic (5.66e-3)" "unprognostic (4.78e-2)" "unprognostic (4.75e-2)" "prognostic unfavorable (3.71e-9)" "unprognostic (6.07e-2)" "unprognostic (7.88e-2)" "unprognostic (3.61e-2)" "unprognostic (1.74e-1)" 203.1 39.2 30.8 130.8 31.0 275.2 171.1 31.9 47.2 226.2 36.9 59.0 28.6 75.5 20.1 116.1 103.6 68.8 82.3 29.9 36.6 42.0 40.2 148.5 187.4 43.4 34.7 28.6 28.0 17.2 39.8 91.7 37.9 68.8 43.3 3.5 70.3 46.5 28.6 85.8 106.6 59.8 35.4 238.3 67.9 9.2 40.0 85.0 59.2 32.6 187.8 104.8 183.8 39.9 932.2 216.7 0.2 0.9 310.5 390.2 213.6 521.7 686.4 362.8 269.3 61.9 263.6 212.9 139.3 632.2 130.3 212.3 132.5 321.3 231.4 265.7 87.9 397.7 111.8 0.5 244.3 228.6 378.0 233.6 141.6 265.3 452.2 213.2 348.5 58.0 380.0 989.0 229.5 1.5 27.4 95.1 66.4 853.4 126.0 127.6 45.0 272.7 134.0 5.2 38.8 0.3 287.1 148.6 316.6 115.0 78.0 180.4 494.8 443.6 170.0 487.7 40.2 1.5 16.2 54.4 675.9 524.8 694.4 644.0 596.4 111.1 451.5 628.4 422.0 602.8 756.5 467.4 718.7 545.6 489.2 405.6 140.1 840.8 636.9 325.0 894.6 934.1 30.8 31.0 31.9 47.2 29.9 36.6 43.4 34.7 37.9 35.4 40.0 39.9 291.0 3.2 13.4 0.0 330.7 107.1 73.4 106.3 54.1 0.6 80.2 51.2 5.2 32.9 27.8 99.3 0.0 18.9 349.7 2.9 0.0 156.1 1.7 3.4 63.5 276.5 10.7 111.2 2.2 197.3 462.9 93.1 71.9 2.2 361.5 0.3 323.8 6.1 430.3 0.0 0.4 8.2 4.1 385.9 492.1 4.6 6.5 403.9 209.9 10.3 243.7 0.4 260.6 1.0 0.1 585.0 7.8 0.7 302.5 72.2 0.2 4.4 5.5 0.4 65.7 5.7 107.6 1.6 8.1 24.0 69.2 50.9 459.5 0.7 10.0 100.3 FZD6 Hfz6 ENSG00000164930 "Frizzled class receptor 6" O60353 8 103298433-103332866 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 73.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 4.0" "Lineage enriched" "Detected in single" 4 "NK-cells: 4.0" "Cell line enhanced" "Detected in many" "hTCEpi: 127.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017991 Approved Supported "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA017991: AB_1849138" "unprognostic (8.22e-3)" "unprognostic (2.64e-1)" "unprognostic (4.75e-2)" "unprognostic (2.57e-1)" "unprognostic (1.22e-2)" "unprognostic (6.99e-2)" "unprognostic (4.01e-2)" "unprognostic (2.74e-1)" "unprognostic (2.43e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.20e-6)" "unprognostic (3.62e-2)" "unprognostic (1.83e-1)" "unprognostic (2.86e-1)" "unprognostic (1.32e-1)" "unprognostic (4.92e-2)" "unprognostic (7.54e-2)" 11.7 10.6 3.0 4.2 2.8 1.0 15.1 3.1 4.3 14.2 5.7 7.0 5.7 13.0 9.5 18.7 23.5 10.6 9.1 2.9 3.0 14.5 4.0 18.6 5.1 3.8 3.1 5.4 11.2 25.3 9.8 15.1 3.8 12.6 7.0 4.6 11.7 10.3 2.0 24.0 4.6 9.3 3.0 4.0 7.4 3.6 3.3 10.0 22.3 5.6 9.9 21.6 10.2 3.2 59.8 11.0 29.6 0.0 7.9 20.6 17.1 31.0 34.1 27.2 17.6 6.2 47.8 0.0 51.4 29.7 9.1 90.3 16.8 65.7 51.0 13.5 18.0 31.4 12.2 8.5 93.4 0.0 0.0 23.0 127.6 29.4 91.5 67.1 58.2 7.0 3.2 27.0 31.5 25.5 29.8 2.7 6.7 4.7 20.6 2.3 12.3 0.0 59.1 39.5 10.0 7.9 44.8 22.8 59.9 15.8 0.0 11.6 4.1 6.1 32.0 24.9 32.7 6.4 3.7 13.3 18.0 0.0 40.4 0.0 0.0 0.1 0.2 0.0 0.0 0.5 0.8 0.4 0.3 0.5 0.9 0.4 0.0 4.0 0.0 0.1 0.4 0.2 3.0 2.8 3.1 4.3 2.9 3.0 3.8 3.1 3.8 3.0 3.3 3.2 38.3 25.6 22.5 10.1 2.8 46.9 15.9 51.1 42.7 4.1 16.1 12.7 4.8 8.6 35.4 12.9 2.1 22.7 2.1 4.9 0.0 11.7 9.6 51.0 5.8 42.0 5.3 6.7 19.9 8.2 7.1 7.0 14.8 73.6 0.0 11.2 13.9 3.7 2.4 6.7 7.3 7.4 26.4 1.0 5.1 2.9 1.2 1.3 14.2 16.9 0.7 11.8 1.0 8.5 3.6 9.5 3.2 1.5 8.6 13.4 2.8 7.1 53.8 4.8 0.0 1.6 7.7 7.0 0.8 41.9 44.6 14.6 3.0 1.7 5.6 23.2 FZD7 FzE3 ENSG00000155760 "Frizzled class receptor 7" O75084 2 202033855-202038441 "G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 30.9;Breast myoepithelial cells: 37.0;Cardiomyocytes: 21.1;Fibroblasts: 23.5;Proximal enterocytes: 21.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 30.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 42.8;BJ hTERT+: 48.4;CAPAN-2: 62.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059979, HPA069165, HPA076183" Approved Supported Vesicles NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 35: Glandular cells - Unknown function" Vesicles "HPA059979: , HPA069165: AB_2686096, HPA076183: " "unprognostic (3.44e-2)" "unprognostic (6.89e-2)" "unprognostic (9.30e-3)" "unprognostic (2.44e-3)" "unprognostic (4.92e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (7.71e-5)" "unprognostic (1.40e-1)" "unprognostic (4.92e-2)" "unprognostic (8.22e-2)" "unprognostic (2.73e-2)" "unprognostic (1.10e-1)" "unprognostic (1.87e-3)" "unprognostic (8.16e-3)" "unprognostic (1.43e-1)" "unprognostic (4.16e-2)" "unprognostic (2.05e-3)" 10.2 3.0 4.9 5.6 4.7 0.4 15.5 30.2 4.3 13.2 6.3 36.7 6.9 18.4 14.1 9.4 16.8 6.3 14.4 8.8 5.0 8.2 1.2 5.3 3.9 5.2 4.9 25.0 1.7 1.1 9.3 5.7 5.5 19.2 5.5 1.3 21.7 23.5 26.7 10.9 10.8 11.1 4.9 1.9 5.9 2.1 4.5 1.1 5.1 9.5 3.8 27.1 15.3 5.6 10.3 5.2 33.2 10.8 10.6 7.9 14.8 42.8 48.4 11.9 13.9 32.2 62.7 0.1 25.1 26.2 7.9 10.6 6.0 1.3 13.7 5.4 8.6 1.1 2.1 2.7 7.2 2.1 2.1 7.6 1.0 6.4 3.7 9.5 0.0 0.7 2.9 2.6 9.8 4.2 0.0 5.7 36.6 2.0 3.5 4.2 6.4 1.1 1.9 6.1 5.5 12.6 5.4 0.4 6.8 26.7 3.8 2.5 0.1 23.8 8.8 15.0 5.4 2.7 2.2 0.1 4.9 0.5 16.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 4.7 30.2 4.3 8.8 5.0 5.2 4.9 5.5 4.9 4.5 5.6 3.5 0.0 8.1 3.6 2.0 10.3 8.3 1.9 14.8 0.0 30.9 37.0 21.1 1.5 0.3 1.8 0.0 0.5 2.0 4.7 1.9 1.6 0.1 1.5 2.0 1.7 1.2 0.0 1.5 0.2 1.1 23.5 2.6 3.6 1.3 7.5 0.7 0.7 1.5 0.0 0.2 9.9 0.0 0.8 5.7 0.5 5.3 2.0 3.6 0.0 0.1 7.5 0.0 0.0 0.1 0.6 2.1 4.9 1.7 6.9 21.3 0.1 0.9 0.6 6.6 13.5 16.3 1.6 2.9 11.4 9.8 0.8 2.5 0.5 7.6 1.8 GAB1 DFNB26 ENSG00000109458 "GRB2 associated binding protein 1" Q13480 4 143336762-143474568 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 114.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 162.7;Microglial cells: 192.0;Oligodendrocyte precursor cells: 288.0;Oligodendrocytes: 1013.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 5.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 74.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034333, HPA066404" Approved Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 14: REH - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoli fibrillar center, Plasma membrane" Cytosol "CAB034333: AB_2107855, HPA066404: " "unprognostic (1.14e-1)" "unprognostic (1.16e-1)" "unprognostic (1.32e-3)" "unprognostic (1.66e-1)" "unprognostic (4.71e-2)" "unprognostic (1.79e-2)" "unprognostic (4.17e-2)" "unprognostic (1.23e-1)" "unprognostic (1.35e-2)" "unprognostic (8.20e-2)" "unprognostic (2.10e-1)" "unprognostic (2.20e-1)" "prognostic favorable (3.91e-5)" "unprognostic (4.99e-2)" "unprognostic (2.70e-1)" "unprognostic (1.68e-1)" "unprognostic (1.91e-1)" 7.9 8.6 23.3 6.7 69.9 11.5 9.9 35.5 30.0 10.6 2.5 19.7 12.1 18.1 14.2 20.4 9.2 12.5 30.5 20.4 34.6 13.9 9.1 17.9 6.1 57.3 45.4 19.5 8.1 11.3 4.3 21.0 47.9 8.5 22.8 6.9 8.9 14.7 13.4 10.7 12.3 17.7 26.4 7.5 11.3 9.2 45.7 5.4 7.5 16.5 8.7 7.1 9.7 114.8 6.7 1.4 16.7 12.1 8.3 7.9 22.0 4.6 15.2 5.4 9.4 12.8 11.2 0.2 1.4 6.5 3.7 3.8 16.2 5.3 6.2 1.0 3.9 12.2 3.7 6.1 5.7 1.6 2.3 9.7 9.5 6.6 4.3 11.5 7.2 0.2 4.1 21.7 3.8 9.7 0.9 0.0 4.8 3.5 5.3 74.6 8.2 8.8 8.4 8.0 3.9 11.8 3.1 13.3 5.6 11.2 8.5 1.6 5.5 6.9 5.4 3.4 3.5 34.6 18.2 26.3 4.7 4.8 5.7 4.1 0.4 0.5 0.0 0.5 0.2 0.9 0.0 0.0 0.5 1.8 0.0 0.0 2.6 5.0 1.7 2.2 0.0 0.3 23.3 69.9 35.5 30.0 20.4 34.6 57.3 45.4 47.9 26.4 45.7 114.8 13.4 28.9 19.0 89.5 13.1 20.3 8.8 3.3 12.0 2.1 11.6 8.9 34.0 8.6 5.3 12.9 0.0 23.5 10.9 26.2 0.0 6.6 0.9 8.8 9.3 16.3 22.2 40.8 162.7 2.6 10.6 14.4 11.2 21.6 2.5 9.6 13.9 7.0 6.1 3.3 62.2 27.8 4.1 11.6 10.2 3.8 20.8 8.8 16.0 192.0 5.6 15.4 1.0 288.0 1013.6 4.9 10.7 18.8 94.4 7.2 9.3 5.4 3.4 0.8 13.1 7.0 14.3 2.0 5.3 19.9 24.9 10.4 2.7 4.4 13.6 13.5 GABRR2 ENSG00000111886 "Gamma-aminobutyric acid type A receptor subunit rho2" P28476 6 89254464-89315299 "Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 25 "retina: 31.4" "Cell type enriched" "Detected in some" 18 "Bipolar cells: 30.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 2.2;U-266/70: 5.1;U-266/84: 1.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (2.05e-2)" "unprognostic (1.47e-4)" "unprognostic (1.56e-1)" "unprognostic (1.88e-4)" "unprognostic (4.19e-1)" "unprognostic (1.07e-1)" "unprognostic (2.24e-2)" "unprognostic (9.13e-2)" "unprognostic (2.87e-1)" "unprognostic (1.10e-2)" "unprognostic (2.65e-1)" "unprognostic (1.41e-1)" "unprognostic (1.54e-6)" "unprognostic (3.69e-2)" "unprognostic (7.81e-2)" "unprognostic (5.79e-2)" "unprognostic (7.15e-3)" 0.4 0.3 0.5 1.2 0.4 0.7 0.2 0.7 0.6 0.2 0.3 0.3 0.7 0.5 0.4 0.1 0.1 0.3 0.2 0.4 0.3 0.4 0.1 0.3 0.8 0.5 0.6 0.2 0.1 0.0 0.0 0.3 0.5 0.3 0.4 31.4 0.3 0.2 0.8 0.3 0.7 0.3 0.3 0.8 0.3 0.2 0.6 1.2 0.3 0.2 0.6 0.2 0.0 0.8 0.0 0.0 0.2 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.5 0.5 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.6 0.1 0.2 0.0 2.2 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.3 0.1 0.8 0.1 0.0 0.2 0.1 0.0 0.0 0.3 0.6 0.0 0.7 0.1 0.2 0.1 0.0 0.3 5.1 1.4 0.2 0.2 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.5 0.4 0.7 0.6 0.4 0.3 0.5 0.6 0.5 0.3 0.6 0.8 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 30.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.7 0.7 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.0 0.0 0.3 0.0 1.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GAL3ST4 FLJ12116 ENSG00000197093 "Galactose-3-O-sulfotransferase 4" Q96RP7 7 100159244-100168617 "Metabolic proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 27.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 37.2;Microglial cells: 23.4;Oligodendrocyte precursor cells: 24.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 4.5;naive CD4 T-cell: 15.0;naive CD8 T-cell: 4.6;plasmacytoid DC: 4.7" "Group enriched" "Detected in many" 29 "dendritic cells: 4.7;T-cells: 15.0" "Cell line enhanced" "Detected in many" "WM-115: 43.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038137, HPA038138" Uncertain Approved Nucleoplasm,Cytosol NA NA 35000 "Cluster 32: T-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm Cytosol "HPA038137: AB_10697239, HPA038138: AB_2675854" "unprognostic (4.22e-2)" "unprognostic (2.97e-2)" "prognostic unfavorable (5.44e-4)" "unprognostic (8.64e-2)" "unprognostic (3.01e-2)" "unprognostic (1.40e-1)" "unprognostic (3.10e-2)" "unprognostic (1.81e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.57e-4)" "unprognostic (2.80e-1)" "unprognostic (2.25e-1)" "prognostic unfavorable (4.14e-4)" "unprognostic (3.98e-2)" "unprognostic (9.67e-2)" "unprognostic (1.89e-2)" "unprognostic (5.36e-2)" 4.3 4.9 9.2 3.9 9.3 0.7 3.7 8.4 12.6 11.0 7.6 6.1 3.8 9.1 3.1 7.8 6.0 5.6 5.0 9.1 9.5 1.4 0.9 5.2 2.9 13.4 9.5 6.3 1.4 3.0 4.2 5.1 10.1 4.8 6.3 0.5 25.6 3.6 1.9 27.7 5.0 9.9 10.7 2.7 2.4 4.8 15.9 22.3 1.9 1.9 3.2 6.7 10.6 13.1 0.1 0.9 5.4 2.3 4.7 9.6 10.9 3.2 3.2 1.8 2.6 0.6 0.2 1.1 0.7 10.4 3.3 12.2 0.3 1.8 0.6 0.1 0.6 0.4 0.2 0.4 3.4 0.3 2.7 11.7 4.6 5.5 0.6 4.0 3.7 4.3 1.6 0.2 3.4 0.4 4.2 0.2 1.9 11.5 1.3 2.7 2.4 0.2 0.0 0.4 0.3 2.2 1.0 0.0 6.7 1.0 0.0 0.3 3.4 0.3 1.6 0.5 0.1 0.2 0.2 2.5 1.9 0.4 43.3 0.0 0.1 0.0 0.5 0.0 0.0 0.1 4.5 0.3 0.0 0.1 15.0 4.6 0.3 0.2 0.1 4.7 1.3 2.2 9.2 9.3 8.4 12.6 9.1 9.5 13.4 9.5 10.1 10.7 15.9 13.1 0.7 0.0 0.5 2.9 0.1 4.2 2.0 3.3 7.4 0.0 2.2 2.4 1.0 1.5 0.9 0.0 0.0 0.3 0.3 1.5 0.0 0.6 0.2 0.2 2.1 1.2 0.0 2.7 0.5 0.0 0.4 7.5 0.0 0.3 0.0 1.2 1.4 0.0 37.2 0.0 0.3 1.3 4.1 1.3 0.8 0.0 4.7 9.6 5.4 23.4 0.7 0.4 0.0 24.6 0.5 0.3 2.5 5.3 0.0 0.5 0.0 0.0 0.1 0.1 0.0 3.7 3.3 0.6 0.3 4.2 8.1 0.8 0.7 0.1 4.1 1.4 GALK2 GK2 ENSG00000156958 "Galactokinase 2" Q01415 15 49155656-49367869 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 92.2;Inhibitory neurons: 90.1;Oligodendrocytes: 109.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043564, HPA048267" Uncertain Approved Nucleoplasm,Cytosol NA NA 24000 "Cluster 44: Non-specific - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 16: U-266 - Nucleosome" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA043564: AB_2678557, HPA048267: AB_2680335" "unprognostic (2.27e-2)" "unprognostic (1.45e-1)" "unprognostic (2.38e-1)" "prognostic favorable (7.31e-4)" "unprognostic (3.04e-1)" "unprognostic (9.78e-2)" "unprognostic (2.66e-1)" "unprognostic (1.95e-1)" "unprognostic (2.30e-1)" "unprognostic (8.67e-3)" "unprognostic (2.25e-2)" "unprognostic (2.43e-1)" "prognostic favorable (1.88e-5)" "unprognostic (2.33e-1)" "unprognostic (9.79e-2)" "unprognostic (2.13e-2)" "unprognostic (1.93e-1)" 10.3 16.8 8.5 8.5 9.3 6.6 11.2 10.1 9.3 12.5 14.8 15.2 20.2 8.5 8.7 8.1 12.2 8.9 12.8 8.7 8.5 30.4 21.1 10.5 8.3 8.6 9.0 9.3 12.2 17.5 9.6 9.9 9.0 9.7 16.2 7.7 9.9 10.9 10.5 9.0 16.6 10.7 8.5 8.9 13.2 7.0 8.3 12.6 14.8 16.9 10.0 9.3 8.5 11.4 14.7 17.1 7.5 10.1 19.1 29.7 21.9 14.7 20.2 14.7 17.2 21.6 15.0 4.8 11.6 15.9 18.0 20.5 30.2 21.6 20.6 26.2 9.1 26.8 15.7 18.4 20.9 19.2 8.2 15.4 38.4 15.7 37.4 16.8 30.2 11.0 27.4 25.5 16.1 15.9 13.9 15.3 3.3 44.0 15.9 16.7 9.5 71.0 27.3 13.8 9.1 6.0 16.6 33.3 29.6 15.0 16.9 18.3 16.6 14.1 9.6 58.4 14.3 20.9 76.2 8.9 22.2 70.1 19.8 45.4 15.3 28.4 18.1 16.7 18.9 14.0 18.0 17.3 15.2 11.1 14.2 14.3 7.6 19.6 17.2 13.3 35.3 13.1 8.5 9.3 10.1 9.3 8.7 8.5 8.6 9.0 9.0 8.5 8.3 11.4 13.6 3.2 14.9 48.6 12.7 5.6 13.6 16.8 9.1 13.3 12.1 10.3 3.1 27.1 14.5 5.5 37.5 14.8 10.6 14.5 29.4 20.0 12.0 19.2 15.7 12.0 9.0 12.0 92.2 13.1 29.0 12.7 18.3 12.0 2.5 9.8 22.9 25.7 20.4 15.2 90.1 25.1 20.3 16.8 5.7 4.8 11.5 12.6 14.2 63.7 16.5 11.6 20.6 41.7 109.5 10.7 16.2 11.3 27.9 8.3 30.5 56.5 34.1 25.8 0.0 13.4 11.6 22.3 5.9 9.0 6.3 25.7 13.9 13.8 19.0 9.7 GALNT15 "GALNT7, GALNTL2, pp-GalNAc-T15" ENSG00000131386 "Polypeptide N-acetylgalactosaminyltransferase 15" Q8N3T1 3 16174680-16231992 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 157.4;brain: 141.7" "Cell type enhanced" "Detected in many" "Adipocytes: 103.9;Astrocytes: 34.6;Early spermatids: 26.6;Endothelial cells: 26.9;Hepatic stellate cells: 41.7;Muller glia cells: 47.4;Oligodendrocytes: 69.3" "Cancer enriched" "Detected in many" 5 "glioma: 21.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "ASC diff: 133.0;ASC TERT1: 128.8;HSkMC: 102.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017076 Uncertain Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 40000 "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" Cytosol "HPA017076: AB_1849458" "unprognostic (3.87e-1)" "unprognostic (4.84e-4)" "unprognostic (6.39e-2)" "unprognostic (8.77e-3)" "unprognostic (2.77e-1)" "unprognostic (2.52e-1)" "unprognostic (7.40e-4)" "unprognostic (4.24e-1)" "unprognostic (2.24e-1)" "unprognostic (8.28e-6)" "unprognostic (5.13e-2)" "unprognostic (2.58e-1)" "unprognostic (2.66e-2)" "unprognostic (1.37e-3)" "unprognostic (1.88e-1)" "unprognostic (8.51e-2)" "unprognostic (1.78e-3)" 157.4 4.9 45.1 1.7 55.8 2.7 87.2 62.5 49.3 12.3 14.4 21.7 3.0 11.4 11.9 12.4 24.9 5.6 18.1 47.9 90.8 11.8 4.0 9.4 4.1 137.6 60.4 22.3 3.6 2.4 3.5 32.3 130.8 6.0 3.9 13.4 25.5 4.7 36.3 41.7 21.2 7.0 102.4 12.3 15.3 9.1 62.8 4.0 18.3 35.3 1.3 33.0 22.8 141.7 0.4 1.3 0.9 1.0 133.0 128.8 0.3 3.4 2.5 0.4 1.3 0.0 0.5 0.5 1.9 7.8 2.3 0.8 0.5 1.4 2.0 0.6 1.4 1.1 1.9 0.0 7.4 1.5 0.4 102.8 0.0 1.2 1.8 2.4 2.8 0.7 0.2 3.0 1.1 1.9 0.0 2.1 0.5 0.8 1.1 0.3 1.1 24.1 0.5 0.5 0.4 0.3 0.4 1.0 0.6 0.6 0.7 1.8 3.9 0.6 4.3 26.8 0.6 1.4 5.1 1.4 2.5 0.4 0.4 0.5 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.2 0.1 0.2 0.1 0.3 0.1 0.0 45.1 55.8 62.5 49.3 47.9 90.8 137.6 60.4 130.8 102.4 62.8 141.7 103.9 0.0 1.7 34.6 0.1 0.5 0.4 0.0 0.0 3.8 1.1 0.9 2.8 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 26.6 0.5 3.3 26.9 0.0 0.0 4.9 0.0 0.1 24.7 0.0 1.0 1.3 0.1 41.7 1.8 0.1 0.0 3.9 0.0 0.0 0.8 2.1 16.7 1.8 0.5 0.0 22.5 0.1 47.4 0.0 5.0 69.3 0.2 0.0 0.7 1.8 2.1 0.0 0.1 0.0 3.2 0.0 7.3 2.1 25.5 0.5 0.1 0.9 0.0 0.2 0.3 0.0 0.3 GATA5 "bB379O24.1, GATAS" ENSG00000130700 "GATA binding protein 5" Q9BWX5 20 62463497-62475995 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 11.2;testis: 11.5;urinary bladder: 15.4" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 22.4;Hepatic stellate cells: 7.9;Intestinal goblet cells: 8.7;Proximal enterocytes: 38.8" "Cancer enhanced" "Detected in many" "stomach cancer: 5.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.4;HEL: 2.9;K-562: 4.6;SiHa: 2.0;T-47d: 4.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA067583 Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Intestine - Brush border" "Cluster 1: K-562 - Erythropoiesis" "Cluster 45: Enterocytes - Digestion" Nucleoplasm Cytosol "HPA067583: AB_2685867" "unprognostic (2.21e-1)" "unprognostic (2.28e-1)" "unprognostic (1.79e-1)" "unprognostic (2.10e-2)" "unprognostic (2.66e-1)" "unprognostic (2.39e-1)" "unprognostic (2.62e-1)" "unprognostic (8.34e-2)" "unprognostic (1.69e-2)" "unprognostic (5.70e-2)" "unprognostic (1.27e-2)" "unprognostic (7.96e-3)" "unprognostic (2.00e-2)" "unprognostic (1.04e-1)" "unprognostic (2.36e-2)" "unprognostic (5.39e-3)" 2.4 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.2 0.2 11.2 3.5 0.3 0.1 9.5 1.4 2.8 0.0 0.0 4.0 0.7 1.9 0.0 0.0 0.0 0.7 0.1 3.4 0.4 0.4 0.0 5.4 0.0 0.0 0.3 0.3 0.0 0.2 10.0 0.7 0.0 0.0 10.9 11.5 0.0 0.0 0.6 0.2 0.0 15.4 1.6 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.4 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.2 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 2.0 0.0 0.0 0.8 4.6 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.2 1.7 22.4 0.2 0.0 0.0 7.9 0.0 0.3 0.0 0.0 8.7 0.0 0.0 0.3 2.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.0 0.0 0.0 0.0 38.8 0.0 0.0 0.0 0.0 0.0 0.4 0.5 1.1 0.0 0.1 0.0 0.0 0.0 3.4 0.0 GBP5 ENSG00000154451 "Guanylate binding protein 5" Q96PP8 1 89258950-89272804 "Predicted intracellular proteins" "Immunity, Inflammatory response" "Antimicrobial, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.9;lymphoid tissue: 73.9" "Cell type enhanced" "Detected in many" "dendritic cells: 39.2;NK-cells: 75.2;Plasma cells: 22.9;T-cells: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "T-reg: 243.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "EFO-21: 6.5;NB-4: 10.0;U-266/70: 20.7;U-937: 31.5" "Low region specificity" "Detected in many" HPA028656 Supported NA NA "Cluster 13: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "HPA028656: AB_10601471" "unprognostic (2.72e-2)" "unprognostic (1.82e-2)" "prognostic favorable (9.54e-4)" "prognostic favorable (3.73e-6)" "unprognostic (8.33e-2)" "unprognostic (8.68e-3)" "unprognostic (3.71e-2)" "unprognostic (6.43e-3)" "unprognostic (2.37e-3)" "prognostic favorable (1.24e-4)" "unprognostic (3.47e-2)" "unprognostic (4.16e-1)" "prognostic unfavorable (5.53e-8)" "unprognostic (2.75e-2)" "unprognostic (3.68e-2)" "unprognostic (1.66e-1)" "unprognostic (4.11e-2)" 3.7 3.3 0.4 73.9 0.5 34.9 4.6 0.4 1.7 3.1 1.5 6.9 5.8 2.3 1.4 2.6 3.1 11.5 2.0 0.4 0.5 2.0 11.1 19.1 54.4 2.9 0.7 2.7 1.1 0.7 1.0 2.8 1.2 2.3 8.0 0.2 4.8 1.2 0.7 1.0 9.0 6.1 0.5 42.7 9.2 4.0 0.8 12.4 2.3 0.9 23.3 12.7 1.4 0.7 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.7 1.2 1.2 0.0 0.1 0.1 6.5 5.3 2.6 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.4 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.2 0.0 0.9 0.6 3.0 0.3 0.0 0.0 10.0 1.4 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.1 0.1 0.6 1.3 0.1 0.0 0.0 4.0 0.1 0.5 0.5 0.0 2.2 20.7 0.5 0.1 0.2 31.5 0.0 0.9 15.3 1.1 97.5 38.0 150.4 4.8 63.1 89.3 6.7 6.0 23.2 35.8 97.9 53.4 44.9 0.7 243.8 38.4 0.4 0.5 0.4 1.7 0.4 0.5 2.9 0.7 1.2 0.5 0.8 0.7 2.1 6.4 5.1 0.0 12.4 0.0 0.2 0.5 0.6 0.0 0.4 0.4 0.7 1.5 4.2 0.0 4.2 0.1 39.2 0.1 0.0 0.0 0.4 3.7 0.4 2.8 0.0 0.8 0.0 1.1 0.0 1.5 2.0 3.9 10.8 0.2 4.6 0.6 4.0 0.0 0.7 0.0 0.0 18.9 1.4 0.2 0.0 17.1 0.0 2.8 10.4 2.9 75.2 0.0 0.0 1.3 0.0 0.0 22.9 0.4 0.0 0.3 8.0 0.4 0.0 0.9 0.9 0.1 2.9 0.9 0.0 0.1 72.9 11.0 0.1 0.1 GCA GCL ENSG00000115271 Grancalcin P28676 2 162318840-162371595 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 325.7" "Cell type enhanced" "Detected in all" "Early spermatids: 185.0;Kupffer cells: 183.3;Macrophages: 153.5;monocytes: 228.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 327.4;neutrophil: 864.2" "Lineage enriched" "Detected in all" 7 "granulocytes: 864.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035033, HPA035034" Enhanced Supported "Plasma membrane,Cytosol" NA NA 1300000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "Plasma membrane" "HPA035033: AB_10669854, HPA035034: AB_10669900" "unprognostic (9.62e-2)" "unprognostic (9.76e-2)" "unprognostic (3.33e-1)" "unprognostic (3.82e-2)" "unprognostic (2.60e-1)" "unprognostic (1.06e-1)" "unprognostic (2.33e-3)" "unprognostic (1.36e-1)" "unprognostic (8.87e-2)" "unprognostic (2.49e-2)" "unprognostic (1.20e-1)" "unprognostic (9.78e-2)" "unprognostic (6.56e-2)" "unprognostic (5.80e-2)" "unprognostic (3.07e-1)" "unprognostic (3.06e-2)" "unprognostic (1.32e-2)" 30.5 13.5 16.4 62.6 23.0 325.7 17.6 20.2 28.8 12.2 11.4 18.0 19.3 9.8 24.6 10.9 16.2 23.0 9.7 15.9 17.7 18.3 15.0 26.5 33.0 25.5 20.7 8.5 16.6 10.4 8.2 25.2 23.6 12.2 19.6 10.6 12.3 9.7 2.7 7.0 18.7 18.8 21.6 70.1 25.1 24.1 19.5 18.4 17.0 14.9 25.4 26.1 5.7 37.3 2.6 4.2 10.7 0.0 2.5 2.2 0.4 4.0 11.1 6.2 11.1 8.7 30.6 3.7 27.0 0.3 14.2 1.6 4.1 12.7 7.7 17.1 16.8 33.5 2.9 17.7 3.0 41.6 9.1 2.8 4.3 5.7 1.2 15.8 0.9 25.9 0.6 12.1 0.5 33.0 0.9 24.2 6.5 22.5 16.4 14.2 2.7 18.5 32.7 18.6 6.9 12.0 5.1 23.3 19.7 12.5 15.8 17.7 0.8 1.6 11.2 17.8 6.2 11.5 23.2 0.6 9.2 15.8 7.7 38.8 132.4 327.4 2.7 78.4 3.5 21.6 4.8 4.8 63.2 21.1 8.1 5.0 864.2 2.5 63.3 17.2 10.2 71.4 16.4 23.0 20.2 28.8 15.9 17.7 25.5 20.7 23.6 21.6 19.5 37.3 28.8 16.0 36.5 10.1 54.5 15.4 28.2 19.6 12.5 10.2 32.6 16.4 4.1 50.1 21.2 33.1 2.1 55.5 17.3 14.4 76.3 49.5 185.0 21.1 9.1 26.4 39.4 36.1 25.9 60.5 20.8 14.4 43.8 24.9 44.9 13.6 48.9 15.0 107.9 11.8 15.4 29.9 32.6 183.3 60.5 32.8 10.8 153.5 16.0 17.8 228.5 21.1 10.3 1.0 98.0 36.5 25.7 6.4 23.4 24.3 18.4 69.7 24.7 4.4 6.6 12.2 18.3 52.6 13.5 15.1 18.2 46.9 16.3 16.7 28.9 21.0 GCFC2 "C2orf3, DNABF, GCF, TCF9" ENSG00000005436 "GC-rich sequence DNA-binding factor 2" P16383 2 75652000-75710985 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077882 Approved Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA077882: AB_2686864" "unprognostic (1.98e-1)" "unprognostic (5.18e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (9.59e-4)" "unprognostic (5.67e-3)" "unprognostic (2.75e-1)" "unprognostic (2.34e-2)" "unprognostic (3.74e-2)" "unprognostic (8.80e-2)" "unprognostic (4.21e-2)" "unprognostic (1.63e-1)" "unprognostic (5.71e-2)" "unprognostic (3.20e-2)" "unprognostic (8.37e-2)" "unprognostic (1.04e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (6.07e-2)" 10.7 10.5 13.8 4.2 16.3 7.4 12.1 14.4 17.3 19.2 9.7 9.7 3.7 11.1 11.4 9.6 13.7 4.7 11.3 12.2 14.4 19.0 28.5 7.8 8.8 13.7 14.5 14.3 14.1 7.5 11.2 6.9 13.9 14.0 3.8 11.7 7.8 5.5 29.1 15.8 8.1 6.3 15.1 12.3 9.4 12.0 14.4 7.6 12.1 9.1 6.5 9.0 10.4 17.3 14.4 13.9 9.8 11.6 5.3 6.7 12.7 9.5 7.7 9.7 9.2 16.7 10.3 14.2 13.4 6.5 11.9 5.5 11.9 6.5 13.0 20.9 25.5 10.9 13.6 44.9 8.3 18.8 10.2 7.2 8.2 4.8 14.5 11.0 11.6 17.6 16.5 8.2 9.3 11.3 19.6 31.8 15.5 10.5 15.3 22.8 20.1 34.6 16.3 15.7 18.0 22.6 12.8 14.5 16.2 6.9 10.8 10.6 12.6 9.3 12.2 13.4 19.3 9.5 17.7 10.8 9.2 11.7 20.7 0.6 8.1 3.8 10.4 5.7 11.9 18.2 9.7 12.1 9.4 12.6 14.3 13.2 0.4 5.4 9.6 13.3 11.5 8.9 13.8 16.3 14.4 17.3 12.2 14.4 13.7 14.5 13.9 15.1 14.4 17.3 11.6 16.0 11.2 49.6 15.7 27.8 20.5 14.0 21.6 11.2 14.4 13.5 22.4 17.2 20.2 12.9 0.0 36.7 14.8 7.3 21.5 16.0 31.5 11.4 18.0 15.0 16.2 12.0 60.8 19.0 23.5 21.9 8.2 8.7 13.9 15.6 13.2 24.9 12.5 16.8 51.7 7.5 8.2 13.9 12.0 75.4 16.8 8.8 14.2 20.6 7.1 10.6 16.5 75.9 75.9 13.8 7.8 9.8 11.3 18.0 6.2 19.3 15.1 9.1 13.1 20.2 13.5 15.5 22.7 16.5 24.7 23.7 13.3 17.4 10.6 16.8 GCNT1 "C2GNT, NACGT2, NAGCT2" ENSG00000187210 "Glucosaminyl (N-acetyl) transferase 1" Q02742 9 76419850-76651203 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 49.9;parathyroid gland: 84.1;stomach 1: 39.0;thyroid gland: 21.5" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 93.8;Kupffer cells: 42.2;Proximal enterocytes: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 21.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 46.2;HSkMC: 39.4;U-2197: 33.9" "Group enriched" "Detected in all" 6 "cerebellum: 7.6;olfactory bulb: 24.9" "Low region specificity" "Detected in all" "HPA003522, HPA003523, HPA031151" Uncertain Supported "Nuclear speckles" NA NA 84000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 18: U-2197 - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear speckles" "HPA003522: , HPA003523: , HPA031151: AB_10602904" "unprognostic (3.14e-1)" "unprognostic (2.01e-1)" "unprognostic (2.19e-1)" "prognostic favorable (8.44e-4)" "unprognostic (5.53e-2)" "unprognostic (2.41e-1)" "unprognostic (1.65e-2)" "unprognostic (3.37e-2)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "unprognostic (1.90e-1)" "unprognostic (3.06e-1)" "unprognostic (3.02e-3)" "unprognostic (4.21e-1)" "unprognostic (2.00e-1)" "unprognostic (2.80e-1)" "prognostic unfavorable (4.96e-4)" 4.0 0.8 1.8 5.0 2.2 5.1 4.6 4.8 1.7 10.6 1.3 8.7 49.9 5.9 0.7 1.8 1.5 2.9 1.2 2.0 0.9 0.9 1.9 4.2 6.7 1.0 1.0 0.7 2.1 84.1 0.9 2.9 1.0 6.3 9.3 0.1 3.8 1.3 0.3 1.1 32.3 4.8 1.0 7.3 39.0 1.6 1.5 3.0 21.5 0.7 4.7 2.2 0.8 1.4 4.7 0.4 0.3 0.1 5.5 26.5 6.7 18.8 8.4 15.0 10.5 4.7 1.1 3.3 1.8 14.1 2.9 4.0 9.5 7.8 16.6 2.3 1.6 8.2 0.4 0.8 46.2 6.0 2.7 39.4 2.0 14.5 15.5 12.2 13.9 4.1 0.0 3.2 15.1 7.1 3.2 9.7 8.8 11.9 1.1 5.3 9.3 1.6 17.5 8.3 2.0 0.0 2.3 2.5 0.1 6.6 0.0 4.1 5.6 9.3 5.9 33.9 8.4 4.7 0.9 0.0 18.7 10.1 2.3 6.1 3.2 21.6 1.5 7.8 0.5 1.9 1.7 1.5 5.8 10.2 0.3 1.1 1.1 5.8 7.3 2.8 2.5 2.1 1.8 2.2 4.8 1.7 2.0 0.9 1.0 1.0 1.0 1.0 1.5 1.4 2.9 0.0 1.7 2.0 8.3 0.9 5.0 34.4 0.6 0.0 8.8 4.2 1.0 0.0 15.6 3.7 0.0 2.1 10.7 16.6 0.0 1.0 20.1 15.1 4.2 5.1 27.6 17.9 11.8 24.3 27.1 3.4 93.8 24.6 10.8 0.6 6.4 0.3 8.1 0.0 1.7 21.3 16.2 42.2 8.5 12.9 0.0 18.6 1.8 15.0 6.7 0.1 8.2 0.5 0.8 12.9 14.5 1.2 2.2 6.8 40.7 1.4 17.0 0.4 0.0 0.9 1.8 1.8 3.3 1.0 0.3 19.0 10.6 0.2 38.4 1.5 GDPD5 "GDE2, PP1665" ENSG00000158555 "Glycerophosphodiester phosphodiesterase domain containing 5" Q8WTR4 11 75434640-75525941 "Enzymes, Predicted membrane proteins" Neurogenesis Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 116.6;retina: 83.5" "Group enriched" "Detected in many" 4 "Bipolar cells: 60.9;Cone photoreceptor cells: 148.0;Early spermatids: 52.1;Late spermatids: 178.0;Rod photoreceptor cells: 88.4;Syncytiotrophoblasts: 46.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 7.7" "Group enriched" "Detected in many" 6 "granulocytes: 7.7;T-cells: 2.0" "Cell line enhanced" "Detected in many" "EFO-21: 32.8;fHDF/TERT166: 32.4;HDLM-2: 66.9;U-2 OS: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065257, HPA066762, HPA069281" Uncertain Approved "Golgi apparatus" No No "Cluster 38: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus" "HPA065257: AB_2685447, HPA066762: AB_2685715, HPA069281: AB_2686107" "unprognostic (1.66e-1)" "unprognostic (1.09e-1)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.48e-1)" "unprognostic (6.12e-2)" "unprognostic (9.97e-3)" "unprognostic (4.05e-1)" "unprognostic (1.44e-1)" "unprognostic (3.49e-1)" "unprognostic (3.07e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.59e-9)" "unprognostic (8.64e-2)" "unprognostic (1.30e-1)" "unprognostic (4.39e-2)" "unprognostic (1.65e-1)" 31.0 8.7 19.5 4.8 22.1 12.8 24.6 17.4 12.9 12.4 6.0 7.3 2.7 17.9 1.8 3.3 10.3 4.3 9.5 10.5 14.5 7.8 8.1 15.2 6.7 14.2 27.0 7.3 38.1 0.8 19.1 14.0 10.2 11.5 1.6 83.5 21.3 5.3 13.1 7.4 10.0 6.5 7.4 116.6 4.8 38.9 42.1 3.1 7.7 8.7 4.7 12.6 9.9 12.4 2.1 7.5 3.2 3.7 2.2 1.1 11.1 2.3 3.1 1.1 0.7 10.0 4.4 14.2 32.8 32.4 8.1 4.7 4.0 3.8 0.6 66.9 3.1 2.6 11.7 21.2 3.2 1.6 10.7 2.4 2.0 0.8 1.6 3.2 26.7 12.7 4.7 6.3 1.5 4.5 3.9 7.1 5.7 3.7 10.6 4.5 0.9 3.9 0.9 3.6 1.7 1.2 4.8 18.3 9.3 4.1 2.7 6.3 7.9 7.5 30.4 5.8 2.6 1.6 0.3 2.8 1.7 8.5 0.8 7.7 0.8 0.5 1.2 0.3 1.7 0.6 1.3 0.9 0.2 0.2 0.7 0.9 0.1 0.0 0.0 0.7 2.0 0.5 19.5 22.1 17.4 12.9 10.5 14.5 14.2 27.0 10.2 7.4 42.1 12.4 4.2 6.4 0.0 1.6 5.4 1.0 0.3 0.7 0.6 60.9 3.6 3.4 3.0 1.5 1.3 0.0 148.0 3.2 9.1 0.5 0.0 4.2 52.1 1.0 10.4 7.0 0.0 8.2 5.0 9.3 1.5 6.6 1.1 1.5 4.5 1.6 20.7 2.4 1.9 5.0 15.8 0.7 0.0 2.8 3.7 178.0 5.9 3.1 5.4 8.4 4.9 8.9 1.0 1.0 0.8 4.7 0.3 2.6 5.0 0.8 0.3 0.1 0.8 88.4 0.0 4.6 1.9 12.9 8.2 0.1 1.1 46.0 7.0 0.9 2.0 0.6 GEM KIR ENSG00000164949 "GTP binding protein overexpressed in skeletal muscle" P55040 8 94249253-94262350 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 229.6" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 721.1;Fibroblasts: 395.9;Langerhans cells: 155.5;Smooth muscle cells: 359.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "myeloid DC: 1.4" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.4" "Cell line enhanced" "Detected in many" "BJ hTERT+: 83.0;U-266/70: 140.6;U-87 MG: 104.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "spinal cord: 24.3" HPA024798 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA024798: AB_10602137" "unprognostic (1.24e-1)" "unprognostic (2.12e-1)" "unprognostic (4.82e-3)" "unprognostic (1.22e-1)" "unprognostic (4.76e-1)" "unprognostic (3.94e-1)" "unprognostic (2.17e-1)" "unprognostic (4.00e-1)" "unprognostic (1.45e-1)" "unprognostic (9.04e-2)" "unprognostic (7.92e-2)" "unprognostic (9.15e-2)" "prognostic unfavorable (1.56e-5)" "unprognostic (1.65e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (4.29e-4)" "unprognostic (2.93e-3)" 56.1 58.4 10.9 35.6 9.6 2.6 36.7 8.3 12.3 57.9 38.7 105.7 16.6 97.2 9.7 59.5 39.0 229.6 63.4 11.0 20.8 32.3 20.2 33.1 23.8 12.7 12.2 19.9 15.7 2.9 27.3 7.3 11.0 31.7 35.9 44.4 13.1 16.8 4.2 10.9 31.1 77.3 8.4 21.9 48.0 3.8 12.2 12.6 23.6 10.8 14.2 90.6 33.6 12.3 1.6 6.1 2.7 0.6 22.9 30.4 0.4 16.1 83.0 21.4 29.8 2.3 4.1 0.0 1.0 6.1 40.1 0.5 2.7 1.4 28.0 12.2 1.4 0.0 0.6 0.0 3.0 0.0 26.3 13.1 0.1 34.1 18.9 24.4 0.9 1.4 0.7 2.7 12.7 0.8 1.0 0.2 4.0 3.4 18.3 0.0 4.9 0.1 7.8 0.0 20.4 12.1 0.0 0.1 2.8 3.4 2.0 0.1 1.2 29.4 8.1 19.2 33.4 140.6 0.9 0.1 104.7 0.1 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 10.9 9.6 8.3 12.3 11.0 20.8 12.7 12.2 11.0 8.4 12.2 12.3 18.4 6.4 25.4 22.2 8.9 68.1 85.7 9.6 721.1 26.8 8.6 35.1 90.8 4.3 4.0 1.8 18.8 0.4 4.1 8.2 0.0 7.3 4.7 26.0 49.2 19.0 25.0 0.0 0.7 0.4 1.4 395.9 54.0 50.3 13.4 1.0 7.1 0.1 2.8 30.3 3.4 2.6 2.0 0.6 155.5 0.3 3.4 43.3 92.5 0.0 0.8 41.9 0.0 0.0 0.3 2.7 17.2 5.7 46.5 20.2 2.1 2.6 1.2 21.4 32.9 55.5 359.5 1.3 1.1 24.1 49.9 3.4 33.4 0.9 4.2 10.6 GEN1 "FLJ40869, Gen" ENSG00000178295 "GEN1 Holliday junction 5' flap endonuclease" Q17RS7 2 17753858-17788946 "Predicted intracellular proteins" "DNA damage, DNA repair" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA020078, HPA021141" Enhanced Approved Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA020078: AB_2670352, HPA021141: AB_2670599" "unprognostic (2.25e-1)" "unprognostic (2.33e-1)" "unprognostic (1.52e-2)" "prognostic unfavorable (1.68e-4)" "unprognostic (8.64e-2)" "unprognostic (1.67e-3)" "unprognostic (7.90e-4)" "unprognostic (4.53e-2)" "unprognostic (1.70e-3)" "unprognostic (8.60e-3)" "unprognostic (8.04e-2)" "unprognostic (6.99e-2)" "unprognostic (1.89e-12)" "unprognostic (3.97e-3)" "unprognostic (1.61e-1)" "unprognostic (3.56e-1)" "unprognostic (1.49e-3)" 1.6 1.8 1.1 4.8 1.0 15.1 3.2 0.7 1.2 2.3 15.4 5.2 3.2 1.8 9.3 5.6 1.4 4.4 2.3 1.5 1.7 1.7 8.6 2.0 10.8 2.1 2.4 0.9 2.2 1.1 3.0 3.9 1.8 2.7 6.9 2.5 5.6 2.7 1.7 7.5 4.5 1.4 1.7 5.1 3.0 8.5 1.6 5.4 1.9 1.5 11.8 1.5 3.7 1.8 29.4 15.0 14.0 9.9 3.2 4.1 23.9 21.3 6.7 9.9 9.6 19.6 13.0 27.4 8.2 7.3 10.4 18.4 16.4 12.8 13.7 21.4 9.1 15.7 16.3 9.5 1.9 20.2 17.0 3.1 4.7 16.8 7.7 3.0 8.0 13.7 21.0 19.6 16.4 14.1 15.2 16.4 9.5 9.4 6.8 17.7 36.3 10.9 5.6 19.6 15.3 20.8 11.5 14.3 7.5 9.5 9.8 10.6 10.7 22.4 9.8 12.2 21.8 13.1 26.0 45.1 9.6 18.3 16.0 0.1 0.4 0.3 0.3 0.3 0.2 1.7 0.3 0.6 0.6 0.7 0.4 0.4 0.1 0.4 0.4 0.6 0.5 0.3 1.1 1.0 0.7 1.2 1.5 1.7 2.1 2.4 1.8 1.7 1.6 1.8 3.6 6.4 3.6 12.1 16.9 2.8 2.7 5.2 5.7 5.7 4.5 3.0 4.4 1.5 8.1 3.7 12.5 4.4 6.9 9.3 0.0 2.1 4.6 4.9 8.5 4.0 1.8 15.3 14.1 2.3 4.8 4.2 17.3 6.6 1.3 14.5 2.2 5.4 3.8 3.3 13.0 7.3 0.0 3.1 1.0 3.7 1.8 4.0 1.8 6.5 2.9 3.8 1.0 12.5 11.0 2.9 4.0 0.7 11.2 3.2 5.3 2.5 5.0 3.6 6.6 15.0 5.3 14.2 11.4 8.1 1.8 3.3 3.7 8.0 7.2 2.9 GFI1 "GFI-1, GFI1A, ZNF163" ENSG00000162676 "Growth factor independent 1 transcriptional repressor" Q99684 1 92473043-92486925 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 53.7;lymphoid tissue: 31.2" "Cell type enhanced" "Detected in some" "dendritic cells: 14.2;Intestinal goblet cells: 12.4;NK-cells: 11.3;Plasma cells: 8.6;T-cells: 16.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HL-60: 61.9;HMC-1: 47.5;NB-4: 64.7;THP-1: 127.7;U-937: 261.3" "Not detected" "Not detected" "Not detected" "Not detected" CAB011197 Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB011197: AB_532302" "unprognostic (5.67e-4)" "unprognostic (8.67e-3)" "prognostic favorable (5.68e-5)" "unprognostic (4.88e-3)" "unprognostic (3.57e-2)" "unprognostic (5.86e-3)" "unprognostic (2.06e-1)" "unprognostic (3.87e-3)" "unprognostic (1.26e-3)" "unprognostic (4.47e-3)" "unprognostic (5.20e-2)" "unprognostic (1.72e-1)" "unprognostic (6.80e-6)" "unprognostic (2.63e-1)" "unprognostic (8.27e-2)" "unprognostic (3.97e-1)" "unprognostic (4.37e-2)" 1.0 0.5 0.1 5.1 0.2 53.7 0.9 0.1 0.1 0.6 0.3 3.6 4.7 0.6 0.5 0.5 0.7 1.9 0.3 0.1 0.1 0.5 1.0 2.8 6.9 0.3 0.1 0.5 9.4 0.2 0.5 0.2 0.2 0.8 4.5 0.0 1.0 0.3 0.2 0.3 5.7 0.4 0.2 7.0 3.2 0.9 0.2 31.2 0.9 0.0 4.4 1.7 0.6 0.2 1.4 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.1 0.1 0.1 1.0 10.3 0.1 0.7 0.0 0.5 0.4 1.2 0.0 0.2 0.0 2.5 1.6 0.2 5.3 0.1 61.9 47.5 0.0 0.0 0.1 0.1 0.3 0.1 17.1 0.4 15.3 0.1 2.1 39.5 64.7 0.0 0.1 0.2 7.8 2.7 3.4 0.0 0.7 0.1 0.1 0.3 0.1 0.3 0.1 0.0 127.7 0.0 0.0 1.5 0.1 0.2 22.2 1.6 4.0 0.0 261.3 0.0 0.0 0.0 0.4 2.1 0.0 1.0 0.0 0.9 1.4 0.0 0.0 0.3 1.9 0.0 0.1 0.0 0.8 0.3 0.2 0.1 0.2 0.1 0.1 0.1 0.1 0.3 0.1 0.2 0.2 0.2 0.2 0.3 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.7 0.0 0.0 0.0 0.0 0.0 14.2 1.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.9 0.0 0.1 1.1 0.2 0.0 0.1 1.4 0.0 0.1 0.0 0.1 12.4 0.0 0.8 0.2 0.2 0.0 0.8 0.0 0.0 0.1 0.0 11.3 0.0 0.1 0.4 0.0 0.0 8.6 0.0 0.7 0.1 0.1 0.0 0.0 0.1 0.2 0.5 3.9 0.0 0.0 0.0 16.4 0.1 0.4 0.0 GFM1 "EFGM, EGF1, GFM, mtEF-G1" ENSG00000168827 "G elongation factor mitochondrial 1" Q96RP9 3 158644527-158695581 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034764, HPA034765, HPA061405" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria Nucleoplasm "HPA034764: AB_2674320, HPA034765: AB_10669849, HPA061405: AB_2684505" "unprognostic (1.26e-1)" "unprognostic (1.61e-1)" "unprognostic (5.48e-3)" "unprognostic (4.48e-3)" "unprognostic (1.84e-1)" "unprognostic (3.40e-1)" "unprognostic (4.75e-2)" "unprognostic (6.05e-2)" "unprognostic (2.48e-1)" "unprognostic (8.36e-2)" "prognostic unfavorable (9.20e-4)" "unprognostic (2.79e-1)" "prognostic favorable (1.16e-7)" "unprognostic (1.62e-1)" "unprognostic (4.78e-1)" "unprognostic (3.32e-2)" "unprognostic (8.78e-2)" 26.7 25.0 12.3 21.7 13.2 24.1 27.8 18.1 21.3 14.1 16.8 30.1 24.9 17.2 20.8 24.1 13.4 17.5 39.0 13.0 15.5 43.7 49.6 18.8 20.7 14.5 13.2 12.7 26.4 40.1 12.0 25.7 15.3 19.6 31.5 46.4 21.0 21.9 63.0 15.2 19.8 20.9 13.7 16.4 23.9 23.5 14.1 16.6 32.1 60.2 20.7 23.5 12.9 15.7 92.2 55.9 25.5 32.0 41.8 30.6 34.2 42.6 49.8 75.9 57.4 73.2 58.7 73.9 54.7 39.2 32.0 55.9 62.5 47.8 84.3 40.6 33.7 56.1 34.6 34.3 48.6 76.7 35.9 37.3 55.7 43.8 41.0 17.6 50.2 43.0 71.7 50.3 67.9 56.9 49.6 30.6 55.7 97.0 29.8 49.8 28.0 132.6 51.0 38.3 48.9 42.8 63.8 96.1 79.1 19.9 132.1 60.0 28.0 46.4 21.0 69.4 74.1 82.7 61.4 138.9 41.8 65.0 52.4 18.9 19.3 13.8 22.2 27.2 28.6 17.0 19.3 23.0 23.3 16.4 22.1 23.9 3.0 25.4 22.0 11.2 17.4 18.4 12.3 13.2 18.1 21.3 13.0 15.5 14.5 13.2 15.3 13.7 14.1 15.7 31.4 19.2 19.0 17.0 26.1 21.5 26.0 20.9 20.5 57.3 23.0 11.9 54.8 22.8 18.9 12.9 31.3 31.6 20.1 22.2 11.7 19.9 15.4 12.4 20.2 36.6 19.3 29.0 39.8 25.0 17.6 20.9 22.4 14.8 19.0 17.7 22.5 61.6 29.0 15.2 43.9 24.5 30.5 20.4 21.5 7.6 22.7 21.7 17.8 18.7 33.8 27.3 16.5 22.6 43.3 20.3 10.5 17.0 19.2 21.7 22.1 37.9 25.1 51.6 13.1 21.5 23.4 34.4 31.6 20.1 21.0 30.8 22.3 41.4 28.9 22.0 GFM2 "EF-G2mt, EFG2, FLJ21661" ENSG00000164347 "GTP dependent ribosome recycling factor mitochondrial 2" Q969S9 5 74721206-74767147 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Protein biosynthesis" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 61.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036863, HPA069871" Uncertain Approved "Nucleoplasm,Midbody ring,Mitochondria" Yes NA "Cluster 11: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "Nucleoplasm, Midbody ring" "HPA036863: AB_2675354, HPA069871: " "unprognostic (2.58e-3)" "unprognostic (7.04e-2)" "unprognostic (8.54e-3)" "unprognostic (1.98e-1)" "unprognostic (4.49e-2)" "unprognostic (2.05e-2)" "unprognostic (1.73e-1)" "unprognostic (1.64e-1)" "unprognostic (1.40e-1)" "unprognostic (3.80e-2)" "unprognostic (2.10e-2)" "unprognostic (1.29e-1)" "prognostic favorable (1.33e-5)" "unprognostic (9.55e-2)" "unprognostic (4.15e-1)" "unprognostic (8.52e-3)" "unprognostic (9.82e-2)" 9.6 18.1 9.7 10.2 10.5 15.0 14.1 10.2 14.5 10.7 16.1 13.9 9.3 11.1 17.4 11.9 23.4 9.0 33.3 10.8 10.7 23.3 34.0 9.0 12.2 9.5 9.1 11.4 10.0 30.4 10.7 13.5 10.0 13.0 15.8 16.8 13.4 11.2 30.6 11.3 10.8 10.8 9.4 8.5 17.9 15.8 10.2 17.2 13.1 38.5 15.5 12.9 7.0 11.1 39.5 34.3 27.2 52.2 20.3 27.1 28.2 41.5 24.7 41.5 44.1 36.4 24.9 39.7 44.9 21.9 65.7 32.1 55.0 59.6 54.8 34.8 35.5 22.9 31.7 27.0 27.1 23.6 26.0 32.1 26.3 33.6 40.5 29.8 30.3 39.4 40.7 32.9 48.5 23.3 32.1 15.1 11.4 14.8 29.7 41.1 43.5 49.3 32.0 24.7 46.6 24.8 46.3 38.1 44.3 30.1 33.0 44.0 24.0 16.2 27.8 20.5 27.2 19.0 38.3 40.1 24.1 34.2 24.6 22.8 6.9 9.2 6.7 7.2 6.6 8.3 5.5 7.5 6.7 7.2 7.5 7.3 3.5 16.0 11.8 4.4 7.0 5.2 9.7 10.5 10.2 14.5 10.8 10.7 9.5 9.1 10.0 9.4 10.2 11.1 6.4 12.8 12.9 19.9 8.5 6.0 7.1 13.0 8.6 9.1 7.7 6.9 11.0 7.2 12.5 7.3 6.2 20.1 7.5 8.9 21.5 9.5 11.5 42.4 9.2 6.4 5.4 17.9 35.7 5.3 15.9 6.3 15.3 13.7 2.5 10.4 5.3 22.4 9.9 16.8 34.1 9.7 30.5 8.5 2.4 2.6 7.2 6.8 8.8 13.1 17.9 13.0 7.2 34.2 29.1 9.8 9.9 7.5 11.4 4.6 8.5 11.2 61.5 9.6 0.0 5.6 7.8 15.2 11.7 10.0 7.0 16.0 7.3 11.1 10.0 7.5 GFRA2 "GDNFRB, NTNRA, RETL2, TRNR2" ENSG00000168546 "GDNF family receptor alpha 2" O00451 8 21690398-21812357 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 9.4;thyroid gland: 8.7" "Group enriched" "Detected in some" 4 "Early spermatids: 91.9;Horizontal cells: 220.4;Late spermatids: 238.1" "Cancer enriched" "Detected in some" 5 "thyroid cancer: 6.2" "Region enhanced" "Detected in many" "cerebral cortex: 5.0" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 9.2" "Group enriched" "Detected in many" 7 "dendritic cells: 2.5;monocytes: 9.2" "Cell line enhanced" "Detected in some" "HEL: 9.1;HMC-1: 21.4;WM-115: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024704, CAB032791" Uncertain Approved Vesicles "Intracellular and membrane" NA NA 9000000 "Cluster 7: Monocytes - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "CAB032791: AB_2110428, HPA024704: AB_1849629" "unprognostic (4.24e-2)" "unprognostic (1.11e-2)" "unprognostic (4.02e-1)" "unprognostic (3.46e-2)" "unprognostic (3.93e-2)" "unprognostic (1.08e-2)" "unprognostic (7.48e-4)" "unprognostic (2.87e-1)" "unprognostic (6.11e-2)" "unprognostic (4.40e-3)" "unprognostic (2.11e-3)" "unprognostic (7.82e-2)" "unprognostic (1.50e-4)" "unprognostic (8.45e-4)" "unprognostic (1.74e-1)" "unprognostic (4.68e-2)" "unprognostic (9.63e-3)" 2.4 1.8 1.2 2.0 1.0 0.6 0.6 0.0 5.0 2.6 0.0 2.1 1.9 0.5 0.2 1.5 1.3 0.6 1.0 1.5 2.2 0.2 0.9 1.2 1.6 0.0 0.8 0.3 0.3 0.1 0.4 7.1 0.0 0.4 1.1 2.6 0.9 1.5 0.1 0.5 1.8 2.0 0.0 7.5 1.0 9.4 1.8 1.1 8.7 0.6 0.8 1.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 21.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 1.9 0.8 0.0 9.2 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.0 0.4 0.0 1.3 0.0 0.0 0.9 1.2 1.0 0.0 5.0 1.5 2.2 0.0 0.8 0.0 0.0 1.8 0.0 0.3 0.0 1.8 1.3 0.1 1.8 0.2 0.0 0.0 4.3 0.1 0.4 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 91.9 0.0 1.2 0.3 0.0 0.0 39.5 0.0 0.1 1.8 0.0 0.1 1.3 0.0 0.7 0.2 0.6 220.4 6.5 0.0 0.0 30.6 25.2 238.1 0.6 11.8 0.0 3.7 0.5 1.9 0.0 2.5 1.1 0.0 0.0 1.9 0.1 0.1 0.0 0.0 0.0 2.1 6.6 0.7 1.8 1.2 7.0 0.0 0.9 0.3 0.2 0.1 0.0 0.1 GGA3 KIAA0154 ENSG00000125447 "Golgi associated, gamma adaptin ear containing, ARF binding protein 3" Q9NZ52 17 75236599-75262363 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022945, HPA024645" Approved Supported "Golgi apparatus" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 16: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Golgi apparatus" "HPA022945: AB_1849639, HPA024645: AB_2671629" "unprognostic (9.16e-2)" "unprognostic (8.89e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (8.26e-4)" "unprognostic (1.20e-1)" "unprognostic (4.60e-3)" "prognostic unfavorable (2.77e-6)" "unprognostic (6.33e-2)" "unprognostic (1.42e-1)" "unprognostic (9.30e-2)" "unprognostic (4.63e-3)" "unprognostic (4.90e-3)" "prognostic unfavorable (3.41e-4)" "unprognostic (1.27e-1)" "unprognostic (2.99e-3)" "unprognostic (1.28e-2)" "unprognostic (9.68e-3)" 11.7 9.8 9.0 13.0 8.4 15.7 10.8 7.7 11.4 12.3 4.3 12.4 11.5 10.8 9.8 17.0 10.2 11.4 12.8 8.4 6.7 11.1 11.6 13.0 17.5 8.9 7.6 15.3 12.3 9.1 9.0 14.6 7.6 10.1 11.7 6.7 12.3 7.8 22.7 15.7 15.0 11.8 6.8 19.6 13.0 11.5 7.8 12.8 9.9 10.5 19.0 11.6 12.2 9.4 16.9 21.1 19.5 11.9 21.5 17.9 22.8 18.5 13.3 24.9 21.2 24.8 18.4 21.4 8.2 16.4 19.9 10.6 13.8 8.0 25.7 15.1 21.4 34.3 19.2 19.6 10.3 32.5 24.3 14.1 19.7 13.6 23.5 13.2 26.5 16.1 37.8 19.1 17.7 17.4 42.5 9.6 13.8 19.6 14.9 16.9 28.0 14.3 17.1 18.4 14.0 23.9 18.5 33.2 14.9 27.3 25.3 17.4 29.6 25.7 18.7 17.4 19.9 19.8 15.1 27.5 20.8 23.0 17.2 5.1 6.8 2.9 5.5 5.9 5.1 3.9 4.9 4.2 6.4 4.7 4.3 4.6 7.3 8.4 5.8 6.6 5.4 6.0 9.0 8.4 7.7 11.4 8.4 6.7 8.9 7.6 7.6 6.8 7.8 9.4 9.5 35.3 21.0 13.4 15.5 2.5 4.9 5.2 8.0 8.1 8.8 7.6 12.6 4.3 9.6 0.0 10.4 10.3 21.2 14.3 5.9 5.2 27.6 10.5 13.6 10.2 0.0 4.6 20.6 7.0 11.0 7.7 21.9 14.7 10.1 12.4 9.7 10.4 12.5 6.7 20.2 10.0 6.1 19.2 7.1 30.1 9.3 19.4 12.4 16.9 20.3 5.9 10.3 18.1 21.2 11.6 9.1 10.1 11.0 8.2 9.5 3.5 10.2 8.9 0.0 7.7 6.1 8.1 6.9 7.8 5.3 13.0 12.2 7.0 12.8 8.5 GGCX VKCFD1 ENSG00000115486 "Gamma-glutamyl carboxylase" P38435 2 85544720-85561547 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Lyase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 118.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 163.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018284 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "HPA018284: AB_1849641" "unprognostic (4.88e-3)" "unprognostic (1.13e-2)" "unprognostic (1.22e-2)" "prognostic unfavorable (1.82e-6)" "unprognostic (5.67e-2)" "unprognostic (1.85e-3)" "unprognostic (2.96e-2)" "unprognostic (3.77e-2)" "unprognostic (5.64e-2)" "unprognostic (2.18e-2)" "unprognostic (6.45e-3)" "unprognostic (5.23e-2)" "unprognostic (8.17e-3)" "unprognostic (7.85e-2)" "unprognostic (2.59e-1)" "unprognostic (7.63e-3)" "unprognostic (9.38e-2)" 13.8 11.0 6.0 8.3 7.4 3.2 10.8 8.3 7.7 10.7 11.7 7.8 7.4 10.5 13.8 9.2 10.5 11.3 9.5 6.9 6.2 16.3 118.8 13.8 6.3 7.4 6.9 12.4 15.8 18.0 7.8 23.4 7.5 10.0 9.9 7.7 14.7 12.1 7.9 9.2 7.3 13.4 7.3 6.2 9.1 4.7 7.0 4.8 12.6 8.6 7.2 12.2 8.8 11.2 17.1 27.2 19.0 21.3 93.8 26.6 42.2 29.9 35.1 21.6 30.4 47.3 20.6 6.1 29.7 49.3 27.1 27.2 13.7 37.7 23.7 10.9 18.7 11.1 17.4 45.2 34.8 7.0 10.1 33.1 22.0 43.8 29.7 35.6 31.0 10.8 13.5 8.7 63.5 22.4 3.5 5.3 8.9 47.7 23.4 6.6 44.6 15.3 30.0 32.5 7.2 12.1 26.8 52.2 28.2 32.1 25.6 6.8 28.6 27.5 23.9 27.1 20.9 6.8 20.1 5.1 26.5 7.1 39.4 3.7 4.2 2.2 1.7 4.4 1.6 0.4 0.7 0.7 2.9 0.4 1.7 1.6 1.7 1.4 2.6 2.4 1.2 2.0 6.0 7.4 8.3 7.7 6.9 6.2 7.4 6.9 7.5 7.3 7.0 11.2 27.1 28.9 40.3 10.1 25.1 18.7 20.6 27.8 13.6 21.6 22.9 19.8 27.9 32.9 24.1 29.5 16.7 60.8 28.4 16.1 7.9 29.9 4.2 16.9 19.4 20.8 14.4 5.7 10.9 39.5 50.2 29.4 11.7 26.8 15.8 17.8 23.9 163.0 31.3 8.4 8.9 17.6 22.4 26.9 29.0 2.2 20.2 24.5 21.4 5.6 29.6 19.5 17.5 9.5 12.6 25.0 12.6 20.3 38.4 16.4 16.2 27.1 16.9 33.6 6.6 42.3 22.8 23.5 11.2 20.0 15.2 53.8 20.8 15.1 16.4 23.6 GGH ENSG00000137563 "Gamma-glutamyl hydrolase" Q92820 8 63014881-63039407 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 125.7;liver: 188.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 510.3;Early spermatids: 471.0;Extravillous trophoblasts: 273.4;Proximal tubular cells: 340.8;Syncytiotrophoblasts: 754.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 30.6" "Lineage enriched" "Detected in all" 5 "dendritic cells: 30.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019296, HPA025226" Approved "Intracellular and membrane" NA NA 1200000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB019296: , HPA025226: AB_1849645" "unprognostic (9.29e-2)" "unprognostic (1.22e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (3.99e-7)" "unprognostic (5.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.65e-4)" "unprognostic (1.95e-2)" "unprognostic (1.60e-1)" "unprognostic (2.11e-2)" "unprognostic (1.32e-1)" "unprognostic (1.69e-2)" "unprognostic (9.62e-3)" "unprognostic (1.50e-1)" "unprognostic (2.36e-1)" "unprognostic (6.50e-2)" 9.8 5.4 11.1 14.2 11.1 43.7 16.5 10.7 14.3 5.9 13.1 54.3 11.3 6.3 4.4 20.7 3.5 4.3 3.1 11.1 12.3 125.7 188.6 8.0 10.9 13.3 11.1 3.1 9.9 13.1 1.9 54.9 13.7 4.4 74.4 2.1 13.0 3.7 2.1 27.2 9.9 11.6 10.1 5.5 8.2 33.9 14.4 17.8 2.4 3.2 22.5 8.5 10.8 11.1 110.5 97.6 97.4 15.7 94.1 39.6 69.6 64.3 105.1 94.2 137.7 144.5 183.8 69.8 18.0 77.1 166.8 87.2 97.2 101.9 138.9 139.0 71.6 112.3 50.3 105.1 17.6 53.5 65.9 29.1 29.2 93.9 50.7 59.4 116.1 66.9 62.4 255.2 177.3 64.3 28.8 71.1 51.0 231.6 86.0 77.6 95.2 98.1 75.8 40.3 38.6 69.9 91.8 103.6 98.5 91.6 116.6 65.8 65.5 104.2 115.6 99.4 111.3 112.6 127.2 88.3 158.0 0.1 185.0 0.0 2.1 2.3 1.1 1.7 0.8 6.5 1.5 1.7 0.9 2.7 1.8 1.9 3.0 4.4 2.0 30.6 2.7 1.9 11.1 11.1 10.7 14.3 11.1 12.3 13.3 11.1 13.7 10.1 14.4 11.1 13.1 16.0 7.3 11.1 26.1 30.2 23.2 66.6 9.1 2.0 14.9 21.0 3.2 17.2 31.1 22.0 0.0 510.3 11.7 49.2 37.2 19.7 471.0 5.4 11.5 13.1 13.2 62.5 11.5 7.4 273.4 27.2 11.7 7.6 10.8 21.4 13.6 219.5 72.4 0.0 8.7 70.7 44.7 21.0 15.5 154.2 5.9 12.0 24.9 1.0 32.1 23.1 2.1 3.5 2.9 4.3 23.7 8.2 106.9 10.5 4.3 340.8 18.3 1.3 26.3 12.8 20.4 80.3 133.0 35.9 43.0 754.5 8.5 9.3 102.0 23.1 GGT6 FLJ90165 ENSG00000167741 "Gamma-glutamyltransferase 6" Q6P531 17 4556927-4560818 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 53.8;intestine: 53.4;salivary gland: 55.8;skin 1: 56.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 208.5;Intestinal goblet cells: 69.4;Paneth cells: 135.8;Proximal enterocytes: 130.9;Undifferentiated cells: 86.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "RT4: 58.5;SK-BR-3: 19.4;T-47d: 60.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023362, HPA027213" Approved NA NA 72000 "Cluster 6: Non-specific - Transcription" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA023362: AB_1848955, HPA027213: AB_10601326" "unprognostic (2.23e-2)" "unprognostic (1.20e-2)" "unprognostic (2.14e-3)" "unprognostic (4.51e-2)" "unprognostic (9.71e-2)" "unprognostic (7.67e-3)" "unprognostic (1.29e-1)" "prognostic favorable (4.35e-4)" "unprognostic (2.10e-1)" "unprognostic (2.33e-1)" "unprognostic (3.07e-2)" "unprognostic (5.06e-2)" "prognostic favorable (9.42e-7)" "unprognostic (1.56e-1)" "unprognostic (5.71e-2)" "unprognostic (9.17e-2)" "unprognostic (8.07e-3)" 0.3 0.6 0.4 5.0 0.5 0.2 9.0 0.7 0.7 7.9 0.4 53.4 44.5 0.4 41.1 53.8 8.5 5.3 0.0 0.5 0.3 39.2 0.4 3.5 0.0 0.5 0.4 0.5 46.8 0.0 0.5 0.0 0.5 6.5 34.0 0.1 55.8 6.4 0.4 56.2 38.4 0.8 0.2 0.1 23.7 0.7 0.4 0.7 0.2 0.0 9.0 18.4 18.8 0.9 3.6 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.8 0.0 0.1 0.0 1.3 0.0 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 6.3 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.4 0.0 58.5 0.2 0.2 0.0 19.4 0.0 0.0 60.5 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.1 0.0 0.4 0.5 0.7 0.7 0.5 0.3 0.5 0.4 0.5 0.2 0.4 0.9 0.1 35.3 6.9 0.0 1.1 4.1 14.7 12.5 5.2 0.0 17.9 11.0 0.2 20.0 38.0 23.9 2.1 0.0 0.3 208.5 21.5 23.8 0.1 7.4 0.3 0.5 6.0 0.0 0.0 38.2 0.0 0.9 24.5 2.6 0.0 0.1 0.4 0.0 0.1 0.0 0.0 69.4 12.2 0.0 1.8 0.2 0.6 0.6 0.0 0.0 2.0 0.1 0.0 0.0 0.0 10.6 135.8 0.0 0.0 5.5 130.9 39.5 45.9 0.3 0.0 0.4 2.3 0.0 0.1 30.6 20.9 0.0 1.0 0.0 86.1 26.7 GHITM "DERP2, HSPC282, My021, PTD010, TMBIM5" ENSG00000165678 "Growth hormone inducible transmembrane protein" Q9H3K2 10 84139509-84153568 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1114.2;Late spermatids: 2559.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016464, HPA061664" Approved Supported Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA016464: AB_1849656, HPA061664: AB_2684579" "unprognostic (6.26e-3)" "unprognostic (1.85e-1)" "unprognostic (2.75e-2)" "unprognostic (1.51e-1)" "unprognostic (4.61e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (5.71e-2)" "unprognostic (4.56e-2)" "unprognostic (1.76e-1)" "unprognostic (1.28e-1)" "unprognostic (8.14e-2)" "unprognostic (5.71e-2)" "prognostic favorable (2.32e-10)" "unprognostic (2.46e-2)" "unprognostic (2.09e-1)" "unprognostic (3.56e-2)" "unprognostic (1.25e-1)" 113.9 179.5 124.3 87.0 133.3 110.6 93.8 138.6 147.7 73.1 150.6 171.2 163.5 76.8 86.1 114.4 71.4 68.9 365.3 136.1 146.1 300.7 271.1 74.1 87.3 136.6 128.1 72.7 77.7 197.3 88.8 70.3 138.5 80.6 166.4 144.3 94.4 84.2 369.3 79.7 137.1 85.7 125.4 73.8 123.1 115.7 137.5 86.5 105.9 456.6 103.3 92.3 76.5 123.1 228.2 230.8 97.1 223.5 162.6 143.3 171.6 153.3 267.4 193.7 180.2 283.1 183.8 178.9 167.7 203.2 170.9 199.9 208.4 200.0 185.9 179.8 157.4 127.7 227.3 281.0 306.5 402.0 200.0 162.7 384.1 200.4 577.8 201.8 169.9 150.5 299.9 324.3 180.4 197.4 143.6 318.9 98.3 184.8 203.2 128.3 89.4 270.5 271.4 179.2 79.4 92.4 154.7 134.1 325.1 111.2 273.7 254.2 145.3 94.0 126.5 138.5 251.1 227.9 265.7 199.9 246.8 364.4 67.1 293.7 284.9 276.5 173.9 304.7 194.2 211.0 178.9 186.0 279.9 177.9 166.6 178.8 223.7 206.7 281.3 145.3 235.3 578.0 124.3 133.3 138.6 147.7 136.1 146.1 136.6 128.1 138.5 125.4 137.5 123.1 94.1 96.1 87.6 23.2 138.0 170.3 185.1 440.9 87.0 135.9 102.2 71.8 689.3 140.2 235.8 158.2 70.9 260.4 134.0 376.0 579.2 295.3 1114.2 58.7 68.6 120.7 125.6 242.9 33.6 232.3 234.9 119.6 107.6 67.1 102.0 79.3 88.5 326.1 267.7 101.0 34.5 206.0 443.5 156.2 169.2 2559.1 110.3 153.0 163.7 16.9 228.3 269.0 114.4 14.6 24.3 223.3 276.3 136.9 167.3 180.1 343.7 802.9 173.4 159.9 144.7 114.5 219.8 263.1 153.2 150.4 170.3 386.0 141.6 158.4 281.4 212.9 GIPC3 "C19orf64, DFNB15, DFNB72, DFNB95" ENSG00000179855 "GIPC PDZ domain containing family member 3" Q8TF64 19 3585478-3593541 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 16.7" "Group enriched" "Detected in some" 4 "Adipocytes: 10.4;Endothelial cells: 6.2;Hepatic stellate cells: 12.8;Rod photoreceptor cells: 19.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 19.0;HMC-1: 11.8;THP-1: 23.1;WM-115: 44.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA067765 Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 77: Retina - Visual perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Nuclear bodies, Golgi apparatus" "HPA067765: " "unprognostic (1.77e-1)" "unprognostic (1.73e-1)" "unprognostic (5.13e-2)" "unprognostic (6.99e-2)" "unprognostic (1.22e-1)" "unprognostic (1.76e-2)" "unprognostic (1.41e-1)" "unprognostic (3.67e-3)" "unprognostic (4.76e-2)" "unprognostic (2.97e-1)" "unprognostic (5.06e-3)" "unprognostic (2.26e-2)" "unprognostic (1.51e-3)" "unprognostic (1.96e-2)" "unprognostic (1.67e-1)" "unprognostic (2.75e-1)" "unprognostic (9.06e-2)" 4.6 2.2 1.4 1.0 1.0 0.3 2.8 1.0 1.1 3.0 0.8 1.9 1.2 2.8 2.9 5.2 2.1 2.1 3.9 1.2 1.2 3.6 1.4 3.8 2.4 1.6 1.2 0.7 0.7 2.7 1.0 1.1 1.6 3.5 1.4 16.7 0.7 2.3 1.7 1.1 4.4 8.3 1.4 3.9 2.0 0.3 1.6 3.1 3.0 1.9 1.6 1.1 1.8 1.1 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.3 0.1 0.9 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 4.4 0.0 1.5 0.0 0.2 6.9 19.0 0.0 0.7 0.0 11.8 0.2 0.0 1.1 0.0 0.0 2.1 0.2 3.2 0.0 0.3 0.0 0.0 1.1 0.7 0.0 1.2 0.5 0.0 0.8 0.0 0.0 0.0 0.1 0.5 0.0 4.7 1.1 0.0 23.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 44.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.0 1.0 1.1 1.2 1.2 1.6 1.2 1.6 1.4 1.6 1.1 10.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.4 0.1 0.3 2.4 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 6.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 12.8 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.8 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.2 1.1 0.0 0.4 0.1 0.3 0.1 0.3 0.1 0.0 0.1 GJA5 CX40 ENSG00000265107 "Gap junction protein alpha 5" P36382 1 147756199-147773362 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Atrial fibrillation, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 36.7;placenta: 85.4" "Group enriched" "Detected in some" 6 "Cytotrophoblasts: 135.3;Extravillous trophoblasts: 345.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "SK-BR-3: 133.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB013080, HPA071370" Enhanced NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB013080: AB_2533263, HPA071370: " "unprognostic (1.25e-1)" "unprognostic (6.34e-2)" "unprognostic (1.22e-2)" "unprognostic (2.94e-2)" "unprognostic (3.88e-2)" "unprognostic (8.95e-2)" "unprognostic (1.23e-3)" "unprognostic (5.50e-2)" "unprognostic (1.38e-1)" "unprognostic (1.16e-1)" "unprognostic (4.27e-2)" "unprognostic (7.57e-2)" "unprognostic (1.97e-2)" "unprognostic (2.44e-1)" "unprognostic (4.41e-2)" "unprognostic (3.43e-2)" "unprognostic (8.93e-2)" 18.6 2.2 2.5 6.0 3.4 0.0 10.5 2.4 4.1 5.5 2.6 4.7 3.4 10.8 2.3 4.8 8.2 6.3 36.7 2.4 2.2 17.1 1.2 26.4 1.7 2.8 2.6 4.0 2.6 3.4 0.5 85.4 2.5 4.0 4.1 0.2 1.6 9.4 2.1 1.4 5.9 8.2 2.6 3.9 3.0 2.9 2.7 0.6 5.3 8.9 2.3 7.4 3.8 2.7 1.8 0.0 0.3 0.0 0.0 0.0 5.7 4.4 2.2 2.2 0.5 0.1 0.2 0.0 1.4 0.7 0.0 0.3 0.0 9.3 3.5 0.0 0.3 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.1 13.1 0.0 0.1 0.1 0.2 133.8 0.0 12.2 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 3.4 2.4 4.1 2.4 2.2 2.8 2.6 2.5 2.6 2.7 2.7 14.3 3.2 4.2 0.0 1.0 0.0 0.0 0.0 0.6 0.0 0.2 1.5 17.7 0.0 0.0 3.7 0.0 135.3 0.1 0.0 0.0 0.0 7.6 0.1 0.3 14.7 0.0 0.0 0.0 0.0 345.3 3.7 0.0 0.1 0.0 19.9 37.9 0.0 15.8 0.0 0.0 0.0 0.0 0.6 0.0 9.8 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 39.5 0.5 11.1 4.3 0.4 0.2 0.3 31.1 0.5 0.1 0.0 0.1 GJB2 "CX26, DFNA3, DFNB1, NSRD1" ENSG00000165474 "Gap junction protein beta 2" P29033 13 20187463-20192938 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Hearing "Deafness, Disease variant, Ectodermal dysplasia, Ichthyosis, Non-syndromic deafness, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 328.1;esophagus: 812.1;vagina: 519.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 69.8;Basal respiratory cells: 237.4;Basal squamous epithelial cells: 55.8;Ionocytes: 50.8;Squamous epithelial cells: 160.9" "Cancer enhanced" "Detected in all" "head and neck cancer: 447.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 144.6;hTCEpi: 105.4;OE19: 76.9;RT4: 169.9" "Low region specificity" "Detected in all" "CAB013093, HPA014362" Uncertain Approved Mitochondria NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "CAB013093: AB_2533903, HPA014362: " "unprognostic (2.21e-1)" "unprognostic (1.25e-3)" "unprognostic (2.43e-2)" "unprognostic (6.14e-2)" "prognostic unfavorable (4.45e-4)" "unprognostic (9.77e-2)" "unprognostic (2.92e-1)" "prognostic unfavorable (6.25e-4)" "unprognostic (1.33e-1)" "unprognostic (3.69e-3)" "prognostic unfavorable (2.90e-4)" "unprognostic (3.22e-2)" "prognostic unfavorable (2.53e-6)" "unprognostic (5.78e-3)" "unprognostic (2.40e-1)" "unprognostic (1.17e-2)" "unprognostic (8.93e-3)" 2.0 0.7 1.3 6.7 1.2 3.8 3.7 2.4 3.1 328.1 5.3 20.8 12.9 2.9 3.4 812.1 0.9 14.0 0.4 1.1 1.7 9.8 47.5 0.7 0.4 1.8 1.7 0.3 1.3 0.1 4.1 0.2 1.7 1.2 17.4 0.0 145.2 0.3 0.4 73.0 10.6 2.6 1.7 0.2 8.1 1.2 7.6 12.5 1.7 1.2 90.4 27.9 519.8 1.6 8.7 0.6 0.0 0.2 0.0 2.9 1.7 0.0 0.0 0.0 0.0 1.3 144.6 0.0 0.7 0.1 1.1 28.9 5.3 14.4 0.1 12.6 1.8 0.1 0.1 0.3 0.0 0.0 5.1 2.4 105.4 1.9 19.5 0.0 0.0 2.1 0.1 10.7 0.2 1.4 1.3 0.0 0.3 76.9 14.4 0.2 0.0 8.3 0.2 169.9 0.1 0.0 0.3 0.1 0.3 1.9 2.2 0.4 0.0 0.2 0.0 2.5 22.2 8.7 9.6 0.0 17.1 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 2.4 3.1 1.1 1.7 1.8 1.7 1.7 1.7 7.6 1.6 0.1 3.2 0.0 2.0 0.6 69.8 16.1 237.4 55.8 0.0 1.3 1.3 0.5 4.3 37.3 1.8 0.0 0.1 0.0 28.0 0.0 4.4 1.5 5.0 1.5 1.3 4.2 0.0 0.0 9.8 0.2 1.7 4.1 19.1 0.0 0.0 0.0 25.2 0.6 0.0 0.0 6.1 50.8 0.6 13.3 1.3 0.0 3.9 1.8 0.0 4.6 0.0 0.0 0.0 0.0 9.2 13.3 0.0 2.7 8.6 10.7 17.5 7.5 0.0 0.0 0.1 4.7 0.8 2.1 160.9 28.7 0.1 0.9 0.0 25.0 21.7 GLB1 "EBP, ELNR1" ENSG00000170266 "Galactosidase beta 1" P16278 3 32996609-33097202 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 857.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008382, HPA040610, HPA069503" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 2700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" Vesicles "Golgi apparatus" "CAB008382: AB_590642, HPA040610: AB_2677039, HPA069503: AB_2686142" "unprognostic (1.51e-2)" "unprognostic (3.66e-2)" "unprognostic (5.02e-3)" "unprognostic (9.66e-3)" "unprognostic (9.61e-3)" "unprognostic (1.04e-1)" "unprognostic (2.31e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.08e-1)" "prognostic favorable (1.14e-5)" "unprognostic (3.05e-1)" "unprognostic (2.33e-1)" "unprognostic (2.20e-1)" "unprognostic (5.85e-2)" 22.0 36.1 12.1 27.8 13.0 21.9 20.5 12.5 14.8 33.4 16.0 43.5 43.0 21.9 103.6 15.4 28.2 32.0 15.5 12.5 14.8 46.0 48.2 42.7 25.8 14.3 12.9 21.4 30.8 59.4 18.5 53.8 15.4 23.2 45.6 14.9 25.3 29.3 7.7 15.8 31.0 30.6 12.4 24.4 35.5 13.5 13.5 17.5 52.8 10.8 23.0 31.8 16.2 15.1 37.4 63.6 39.8 48.3 241.9 123.7 857.2 59.1 157.6 73.7 95.1 91.3 86.5 17.9 50.9 120.9 53.9 35.1 38.1 75.5 53.7 104.9 33.0 69.9 35.3 47.4 124.3 50.5 69.9 144.9 70.2 67.0 39.2 144.1 116.5 24.7 64.3 67.0 81.8 44.6 29.6 31.6 26.4 78.0 27.0 24.7 26.4 86.6 78.4 54.4 12.0 40.3 75.0 120.2 74.4 69.3 80.3 130.2 67.7 46.8 32.2 65.2 50.1 53.2 87.9 5.9 99.6 71.2 36.7 43.9 146.2 86.4 29.2 125.8 40.4 37.9 34.3 31.8 166.5 35.6 17.9 21.8 56.6 26.0 92.1 35.1 77.1 91.9 12.1 13.0 12.5 14.8 12.5 14.8 14.3 12.9 15.4 12.4 13.5 15.1 8.7 19.2 25.3 39.2 18.6 6.0 13.6 60.1 10.8 11.3 11.5 7.5 9.1 34.3 43.3 27.6 6.2 100.1 14.1 41.9 27.4 53.5 24.8 18.7 16.0 17.4 16.9 20.6 46.7 35.4 55.3 29.2 26.0 27.1 26.6 20.6 19.6 39.7 79.5 5.0 46.0 23.5 40.7 43.9 13.9 5.0 15.2 41.7 14.2 23.4 64.6 16.5 10.3 27.2 24.2 28.1 43.4 21.1 19.8 9.9 36.2 33.1 31.0 16.2 13.1 12.9 16.3 1.0 6.6 10.1 3.4 49.1 18.7 51.0 32.0 12.1 GLI3 "ACLS, GCPS, PAP-A, PAPA, PAPA1, PAPB, PHS, PPDIV" ENSG00000106571 "GLI family zinc finger 3" P10071 7 41960949-42264100 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 8 "Astrocytes: 301.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 47.1;WM-115: 34.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005534 Approved Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "Nucleoli, Vesicles" "HPA005534: AB_1078973" "unprognostic (2.53e-1)" "unprognostic (2.41e-2)" "unprognostic (7.58e-2)" "unprognostic (8.22e-3)" "unprognostic (1.10e-1)" "unprognostic (1.28e-2)" "unprognostic (1.01e-1)" "unprognostic (5.35e-3)" "unprognostic (2.24e-1)" "unprognostic (7.38e-2)" "unprognostic (4.03e-1)" "unprognostic (3.54e-2)" "unprognostic (1.48e-5)" "unprognostic (9.13e-3)" "unprognostic (5.41e-2)" "unprognostic (3.21e-3)" "unprognostic (7.00e-2)" 6.1 1.9 9.2 3.6 8.8 0.1 8.9 1.0 5.4 7.2 0.0 11.6 1.2 11.8 2.7 3.7 8.2 3.8 1.6 6.3 5.5 1.7 0.3 3.4 0.9 1.7 10.4 13.2 0.7 0.5 1.1 11.9 3.0 5.5 2.9 1.8 2.8 8.2 1.1 8.3 3.4 10.7 0.5 1.1 2.6 1.7 14.4 3.0 4.6 2.3 1.7 4.8 7.3 2.3 0.0 0.0 47.1 0.4 16.9 23.6 3.5 3.1 9.0 9.3 12.8 0.0 0.0 0.0 1.7 22.1 22.7 10.1 8.7 8.9 10.8 0.0 7.0 0.0 6.0 0.0 9.0 0.0 0.1 21.0 12.9 10.6 6.8 5.7 10.6 5.4 0.0 0.2 5.6 5.6 0.4 0.0 20.9 0.0 21.2 12.4 0.1 1.4 0.2 6.4 1.5 0.0 6.3 7.0 4.1 23.8 8.0 0.1 11.3 13.6 18.8 16.0 6.0 0.1 0.0 0.0 7.3 0.2 34.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 8.8 1.0 5.4 6.3 5.5 1.7 10.4 3.0 0.5 14.4 2.3 2.9 0.0 7.7 301.3 0.2 23.5 7.2 8.5 31.9 1.6 20.5 27.1 1.8 0.0 2.3 1.8 0.0 21.1 0.5 0.0 0.0 0.0 16.6 2.4 12.6 3.4 0.0 0.0 0.8 0.0 13.6 25.9 0.0 4.6 1.3 10.5 3.9 0.0 3.3 0.0 3.6 0.1 6.1 0.3 6.3 5.4 19.3 0.4 8.8 22.5 0.0 13.6 0.0 8.5 0.7 0.1 0.0 3.4 1.2 6.6 0.0 3.8 1.5 1.1 13.1 17.0 12.1 0.3 2.2 7.9 15.5 34.2 0.7 5.2 0.1 5.0 GLP2R ENSG00000065325 "Glucagon like peptide 2 receptor" O95838 17 9822206-9892099 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 12.2;intestine: 13.5;urinary bladder: 11.8" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 4.2;Excitatory neurons: 6.4;Leydig cells: 3.1;Rod photoreceptor cells: 23.3" "Cancer enhanced" "Detected in single" "pancreatic cancer: 1.1" "Group enriched" "Detected in many" 6 "basal ganglia: 3.0;cerebral cortex: 3.6;hippocampal formation: 3.2;white matter: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HeLa: 78.1" "Group enriched" "Detected in some" 5 "cerebral cortex: 2.1;hippocampal formation: 2.4" "Low region specificity" "Detected in all" "CAB022690, HPA049244" Supported Supported "Plasma membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "CAB022690: , HPA049244: AB_2680690" "unprognostic (2.14e-1)" "unprognostic (2.45e-3)" "unprognostic (2.66e-3)" "unprognostic (2.21e-2)" "unprognostic (3.81e-3)" "unprognostic (2.09e-1)" "unprognostic (1.39e-2)" "unprognostic (5.15e-2)" "unprognostic (7.63e-2)" "unprognostic (7.14e-2)" "unprognostic (2.19e-1)" "unprognostic (6.16e-3)" "unprognostic (3.40e-8)" "unprognostic (9.53e-5)" "unprognostic (5.51e-2)" "unprognostic (3.92e-1)" "unprognostic (6.48e-3)" 8.1 0.3 0.4 0.7 3.0 0.0 0.8 0.0 3.6 6.0 0.0 13.5 9.9 1.2 0.0 0.7 1.6 12.2 0.6 3.2 0.0 0.3 2.7 1.0 0.6 0.0 0.2 0.4 1.6 0.0 0.0 1.1 0.0 0.1 6.0 3.4 0.0 0.1 0.1 0.1 8.2 1.9 0.0 0.1 3.7 0.4 0.0 0.1 0.2 0.2 0.2 11.8 1.5 1.7 0.0 16.6 0.0 0.0 0.8 0.0 0.8 0.0 0.3 0.0 0.1 0.0 0.5 0.0 0.0 0.0 2.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 78.1 0.6 1.0 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.0 0.0 3.6 3.2 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 6.4 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.4 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.5 0.0 1.5 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 23.3 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GLUD2 GLUDP1 ENSG00000182890 "Glutamate dehydrogenase 2" P49448 X 121047610-121050094 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "liver: 3.9;testis: 15.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.6;Cytotrophoblasts: 4.6;Early spermatids: 2.6;Hepatocytes: 4.6;Proximal tubular cells: 3.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 3.7;K-562: 4.3;OE19: 2.1;SK-MEL-30: 5.5;THP-1: 2.7;WM-115: 6.0" "HPA042492, HPA044839, HPA061369" Uncertain Approved Mitochondria NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA042492: AB_2678024, HPA044839: AB_2679107, HPA061369: AB_2684494" "unprognostic (1.44e-1)" "unprognostic (5.49e-2)" "unprognostic (1.90e-2)" "unprognostic (1.39e-2)" "unprognostic (1.27e-3)" "unprognostic (1.29e-1)" "unprognostic (1.77e-2)" "unprognostic (1.24e-1)" "unprognostic (2.23e-1)" "unprognostic (2.42e-1)" "unprognostic (2.61e-1)" "unprognostic (2.35e-1)" "prognostic favorable (1.98e-4)" "unprognostic (1.04e-2)" "unprognostic (1.49e-2)" "unprognostic (4.77e-3)" "unprognostic (5.96e-2)" 1.7 1.7 0.0 0.1 0.3 0.0 1.2 0.0 0.8 0.4 0.5 0.5 0.0 0.4 1.7 0.5 0.4 0.4 0.9 0.4 0.0 1.6 3.9 0.5 0.1 0.0 0.0 0.4 1.0 0.5 0.4 0.8 0.0 0.4 0.0 0.1 0.6 0.2 0.5 0.6 0.4 0.1 0.0 0.1 0.6 15.4 0.1 0.0 0.4 0.1 0.1 0.4 0.4 0.1 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.8 0.0 0.0 0.7 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 5.5 0.1 1.2 2.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.8 0.0 0.0 2.3 0.1 0.0 0.5 0.0 0.6 0.0 0.4 0.1 2.6 0.0 0.0 0.0 2.1 4.6 0.1 0.1 1.9 0.2 2.6 0.6 0.8 0.9 0.0 0.0 1.2 0.4 0.5 0.8 0.0 0.5 0.0 0.1 0.0 4.6 0.5 0.0 0.4 0.1 0.0 1.2 0.3 2.2 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.4 0.2 3.3 0.0 0.1 0.0 0.9 0.4 1.2 1.0 0.1 0.1 2.5 0.3 0.7 0.2 0.3 GNE "IBM2, Uae1" ENSG00000159921 "Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase" Q9Y223 9 36214441-36277042 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Allosteric enzyme, Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "intestine: 48.4;liver: 90.5;salivary gland: 55.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 59.3;Hepatocytes: 119.3;Intestinal goblet cells: 88.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 107.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007045, HPA027258" Approved Supported Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "HPA007045: AB_1079003, HPA027258: AB_1849873" "unprognostic (7.54e-2)" "unprognostic (1.61e-2)" "unprognostic (1.07e-3)" "unprognostic (7.28e-2)" "unprognostic (7.00e-2)" "unprognostic (1.85e-2)" "unprognostic (2.78e-3)" "unprognostic (5.39e-2)" "unprognostic (1.73e-1)" "unprognostic (1.70e-2)" "unprognostic (2.88e-3)" "unprognostic (4.20e-2)" "prognostic favorable (9.28e-11)" "unprognostic (2.90e-1)" "unprognostic (8.28e-2)" "unprognostic (2.95e-1)" "unprognostic (1.72e-2)" 11.9 9.0 5.5 8.7 7.4 15.5 15.8 8.9 6.5 11.3 7.9 34.0 4.3 10.3 3.5 11.6 9.1 7.4 7.7 5.5 7.3 10.0 90.5 6.8 7.3 7.7 7.3 14.8 10.2 6.1 4.8 14.2 8.9 15.3 48.4 8.0 55.3 7.2 7.9 3.8 7.6 11.7 6.6 6.2 4.6 4.8 7.1 6.2 6.9 15.3 9.5 14.2 7.5 10.5 9.9 44.4 20.1 17.1 22.5 22.4 29.9 13.5 17.9 19.5 25.1 10.5 32.6 13.5 14.2 24.2 50.5 3.9 15.3 4.6 21.8 25.1 1.4 11.0 26.0 15.2 15.4 0.2 31.2 14.4 4.6 32.0 30.6 14.3 8.4 20.7 14.4 27.3 19.3 1.8 19.1 6.3 11.8 6.7 23.7 15.5 16.3 3.8 107.7 19.4 16.7 15.2 13.7 5.3 12.6 7.1 4.8 12.0 12.2 12.7 12.9 15.5 12.2 11.7 26.0 7.0 17.0 9.8 18.2 0.2 0.5 0.2 0.7 0.6 0.5 0.6 0.9 0.8 0.4 0.9 1.0 1.2 0.3 0.7 0.8 0.6 0.4 0.6 5.5 7.4 8.9 6.5 5.5 7.3 7.7 7.3 8.9 6.6 7.1 10.5 9.7 9.6 10.0 9.4 7.1 1.9 3.1 6.7 1.8 8.4 8.2 7.5 6.7 10.0 16.9 9.2 6.2 8.6 4.3 59.3 1.9 10.4 3.4 7.2 12.1 6.3 11.5 7.8 12.8 6.0 9.5 8.3 2.6 10.6 10.1 9.1 7.1 119.3 2.9 11.8 15.6 88.1 16.2 7.8 4.4 2.4 10.8 5.4 1.8 5.6 6.1 1.9 2.1 32.2 28.2 5.3 20.3 6.4 7.9 6.9 2.9 2.2 18.8 6.9 13.1 10.0 6.3 1.8 2.7 1.2 1.6 19.8 5.7 2.3 26.8 13.4 GNG11 GNGT11 ENSG00000127920 "G protein subunit gamma 11" P61952 7 93921735-93928610 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Adipocytes: 1903.6;Endothelial cells: 1236.2;Hepatic stellate cells: 994.2;Macrophages: 481.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 20.5;neutrophil: 9.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 20.5" "Cell line enhanced" "Detected in many" "EFO-21: 219.9;HUVEC TERT2: 349.6;SK-MEL-30: 221.8;TIME: 201.1;U-87 MG: 187.1" "Low region specificity" "Detected in all" HPA045255 Uncertain NA NA 3400000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "HPA045255: AB_10794781" "unprognostic (1.30e-1)" "unprognostic (8.04e-2)" "unprognostic (2.53e-1)" "unprognostic (4.89e-3)" "unprognostic (4.94e-2)" "unprognostic (2.63e-2)" "unprognostic (2.58e-2)" "unprognostic (3.58e-2)" "unprognostic (3.27e-2)" "unprognostic (1.88e-1)" "unprognostic (1.42e-1)" "unprognostic (2.62e-2)" "unprognostic (1.91e-2)" "unprognostic (2.14e-3)" "unprognostic (1.93e-1)" "unprognostic (2.94e-1)" "unprognostic (4.71e-3)" 75.5 16.8 14.4 8.1 14.6 2.5 64.4 14.7 22.0 24.9 13.7 23.5 6.7 26.8 10.9 10.9 33.5 15.5 48.3 14.1 14.7 34.9 12.1 39.8 7.8 14.9 14.6 56.7 8.8 4.4 9.3 85.9 15.3 15.8 6.4 1.5 9.1 17.9 15.4 11.4 16.1 16.7 15.1 39.0 16.0 3.3 16.1 19.0 29.1 18.6 3.5 27.9 18.4 14.9 0.2 34.2 67.2 31.0 51.2 40.0 0.0 34.8 67.7 19.0 26.7 0.1 2.9 0.0 219.9 17.5 79.9 0.5 0.5 3.2 23.8 0.2 2.0 11.0 35.9 0.0 81.8 0.0 0.1 13.4 0.1 61.0 6.0 78.7 349.6 0.0 0.1 0.2 85.9 0.0 0.1 0.1 5.8 0.0 10.4 32.5 7.6 0.1 41.3 0.0 0.1 67.2 0.0 0.2 221.8 8.6 144.4 2.4 201.1 93.4 10.4 68.3 3.9 0.0 0.2 0.7 187.1 0.0 81.8 20.5 0.7 0.3 0.1 0.1 0.2 2.3 0.0 0.0 1.0 2.0 0.2 0.0 9.8 0.0 0.1 3.7 0.1 50.2 14.4 14.6 14.7 22.0 14.1 14.7 14.9 14.6 15.3 15.1 16.1 14.9 1903.6 12.8 27.3 1.3 20.6 83.6 11.8 3.1 5.7 0.7 15.2 26.8 94.8 11.5 3.1 187.6 0.0 2.3 15.4 0.1 74.3 135.7 5.9 124.1 94.6 1236.2 0.0 40.6 0.0 5.7 12.9 207.3 0.5 236.4 2.5 12.7 994.2 11.1 17.0 0.0 0.0 0.3 18.3 55.9 89.5 17.0 82.3 481.1 188.5 26.2 49.6 9.2 41.2 0.5 0.2 4.3 0.0 86.9 8.0 11.0 0.0 12.9 1.7 4.7 151.2 115.5 165.0 1.9 7.6 2.7 65.8 23.8 15.9 109.9 0.0 4.5 GNPNAT1 "FLJ10607, Gpnat1" ENSG00000100522 "Glucosamine-phosphate N-acetyltransferase 1" Q96EK6 14 52775193-52791668 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 77.1" "Cell type enhanced" "Detected in all" "Hepatocytes: 89.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044647 Approved NA NA 72000 "Cluster 27: Non-specific - Gene expression" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" "HPA044647: AB_10795986" "unprognostic (4.55e-3)" "unprognostic (1.19e-2)" "unprognostic (4.47e-3)" "unprognostic (5.18e-3)" "unprognostic (4.23e-1)" "unprognostic (1.52e-2)" "unprognostic (1.21e-1)" "unprognostic (3.19e-3)" "unprognostic (1.03e-1)" "unprognostic (6.81e-2)" "prognostic unfavorable (8.52e-5)" "unprognostic (5.82e-2)" "unprognostic (3.22e-3)" "unprognostic (2.16e-2)" "unprognostic (1.68e-1)" "unprognostic (1.31e-1)" "unprognostic (4.05e-2)" 21.5 7.3 4.8 11.1 5.5 3.9 16.8 6.9 6.1 14.6 5.0 18.4 15.0 9.2 9.5 8.5 8.4 11.4 5.4 5.9 5.8 13.6 77.1 6.0 7.3 4.9 4.7 9.3 25.4 8.0 5.8 10.5 5.4 15.5 22.0 5.6 19.3 7.0 11.2 6.7 14.1 10.7 4.9 5.5 19.7 15.3 5.1 5.8 8.5 7.3 8.5 13.8 6.1 6.2 99.8 37.6 30.5 34.7 32.0 73.8 49.9 63.6 41.4 53.5 54.8 43.4 59.1 56.3 34.6 64.2 26.2 40.0 59.2 64.0 92.9 32.4 31.1 38.1 36.2 55.1 46.2 42.7 19.5 29.9 53.1 92.9 99.5 27.7 62.1 35.3 36.7 13.4 70.8 85.6 52.0 21.9 31.8 129.1 67.6 34.7 14.4 33.9 51.2 51.3 30.6 42.8 54.1 70.5 46.6 20.8 83.4 14.6 70.1 55.2 56.9 97.6 50.0 14.0 28.4 24.4 26.1 27.4 32.8 6.4 1.7 0.1 5.0 2.1 6.0 4.6 5.2 4.6 4.0 5.1 5.9 4.7 0.6 5.5 5.0 2.4 6.8 3.1 4.8 5.5 6.9 6.1 5.9 5.8 4.9 4.7 5.4 4.9 5.1 6.2 14.1 16.0 12.1 5.2 10.7 19.2 33.7 19.1 10.2 9.6 23.6 16.3 3.6 18.6 18.5 12.9 4.2 23.3 10.6 13.4 33.2 40.3 43.8 16.0 25.5 17.7 5.4 13.3 16.5 37.6 74.8 25.8 32.6 39.5 7.0 16.5 12.1 89.4 15.5 3.3 10.8 61.0 10.2 6.0 9.3 11.8 19.6 8.6 7.2 8.4 5.4 5.3 18.6 9.0 9.0 45.9 14.0 18.0 13.8 42.0 8.0 16.1 13.0 6.4 19.7 18.3 24.7 71.2 7.2 22.3 21.3 12.2 10.6 13.7 30.1 38.1 GOLGA7B "bA451M19.3, bA459F3.4, C10orf132, C10orf133" ENSG00000155265 "Golgin A7 family member B" Q2TAP0 10 97849843-97871580 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.0;choroid plexus: 26.2;epididymis: 23.4" "Cell type enhanced" "Detected in many" "Astrocytes: 25.5;Excitatory neurons: 33.6;Inhibitory neurons: 21.2;Late spermatids: 16.6;Rod photoreceptor cells: 18.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 5.3;GAMG: 14.5;HDLM-2: 5.7;SK-MEL-30: 22.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046878 Uncertain NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA046878: AB_2679854" "unprognostic (7.90e-2)" "unprognostic (1.70e-3)" "unprognostic (7.10e-3)" "unprognostic (1.06e-2)" "unprognostic (8.97e-2)" "unprognostic (1.54e-1)" "unprognostic (6.20e-4)" "unprognostic (1.95e-1)" "unprognostic (4.45e-1)" "unprognostic (2.49e-1)" "unprognostic (8.89e-2)" "unprognostic (4.13e-2)" "unprognostic (1.15e-7)" "unprognostic (2.12e-1)" "unprognostic (1.47e-1)" "unprognostic (1.04e-3)" "unprognostic (5.90e-3)" 1.2 2.3 28.7 0.8 30.7 0.2 1.1 33.9 36.0 1.0 26.2 1.1 1.5 0.2 23.4 2.6 0.4 0.4 5.6 32.9 28.0 0.2 0.6 0.7 1.4 29.2 29.2 0.1 8.0 0.0 9.3 0.2 27.5 0.5 0.5 16.9 0.7 0.5 4.6 14.5 2.0 0.1 25.1 0.5 1.0 1.3 29.8 0.3 0.9 3.2 1.1 0.6 2.0 30.0 5.3 1.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 2.0 0.0 0.1 0.0 14.5 1.9 0.0 0.4 0.0 5.7 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 1.0 0.3 0.0 1.8 0.1 0.1 0.3 0.8 1.4 0.0 1.0 22.6 0.0 2.1 0.1 0.1 0.1 0.0 0.0 0.2 1.7 0.8 0.0 3.9 2.3 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.0 28.7 30.7 33.9 36.0 32.9 28.0 29.2 29.2 27.5 25.1 29.8 30.0 0.2 0.0 0.5 25.5 0.0 12.5 0.1 0.7 0.0 6.4 0.6 4.4 2.3 12.8 0.2 1.8 2.1 0.0 3.2 0.3 0.0 6.4 5.4 0.3 0.4 0.5 12.0 0.0 33.6 4.3 0.0 0.6 0.0 0.4 0.0 0.0 0.4 0.0 5.1 3.3 21.2 1.1 0.0 0.0 1.2 16.6 0.3 0.2 7.2 5.6 0.6 3.2 3.1 2.5 1.9 7.4 0.1 0.4 0.0 0.3 1.2 0.0 0.0 18.7 0.0 1.5 0.3 3.9 2.3 0.0 5.1 0.0 2.9 0.0 0.4 0.3 GOLIM4 "GIMPC, GOLPH4, GPP130, P138" ENSG00000173905 "Golgi integral membrane protein 4" O00461 3 168008689-168095924 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 370.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 10.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001677, HPA002315" Enhanced Enhanced "Golgi apparatus" NA NA 1000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "HPA001677: AB_1079017, HPA002315: AB_1079018" "unprognostic (6.88e-2)" "unprognostic (1.10e-1)" "unprognostic (1.19e-1)" "unprognostic (6.27e-2)" "unprognostic (2.11e-1)" "unprognostic (4.76e-2)" "unprognostic (2.44e-1)" "unprognostic (5.17e-2)" "unprognostic (1.39e-1)" "unprognostic (6.46e-2)" "unprognostic (1.10e-1)" "unprognostic (6.31e-2)" "unprognostic (1.84e-3)" "unprognostic (9.03e-2)" "unprognostic (1.19e-1)" "unprognostic (1.30e-1)" "unprognostic (9.62e-3)" 24.8 12.6 25.4 21.4 23.0 9.0 12.9 24.7 32.1 16.8 13.9 53.4 65.8 21.9 8.9 15.7 15.7 28.5 54.6 27.7 34.8 31.3 59.2 29.1 11.3 39.5 29.5 19.9 11.9 12.8 9.6 22.4 40.1 15.2 51.1 53.0 17.3 13.6 32.4 9.3 85.2 26.6 35.1 23.0 24.3 9.0 27.5 6.5 19.0 30.7 9.5 16.8 10.7 33.6 23.7 34.5 47.8 30.4 79.7 58.6 14.5 135.8 72.4 36.3 33.2 38.7 28.4 51.6 159.1 82.4 58.4 42.5 44.4 39.9 54.9 81.3 57.0 83.8 100.2 48.1 32.1 80.5 45.8 61.5 20.9 33.4 32.8 32.2 42.1 0.0 43.7 146.2 41.9 39.2 0.1 21.8 46.9 44.2 36.6 0.1 48.1 72.2 20.6 8.5 42.9 55.5 83.5 25.1 28.4 31.7 30.9 36.1 79.0 114.9 44.2 81.3 110.1 56.4 43.4 109.4 57.1 47.4 52.4 3.2 2.5 10.8 0.6 2.8 0.2 1.2 0.1 0.5 3.3 2.0 0.0 0.2 0.0 5.5 2.3 4.0 0.0 0.7 25.4 23.0 24.7 32.1 27.7 34.8 39.5 29.5 40.1 35.1 27.5 33.6 74.9 48.1 124.8 141.0 11.1 41.4 24.4 18.3 41.5 16.2 21.3 20.6 157.3 67.2 23.3 36.8 37.5 11.4 33.5 184.5 17.6 21.8 1.7 20.6 51.5 70.9 63.3 33.9 18.1 29.6 17.2 119.2 34.1 30.9 58.3 23.3 45.3 178.8 39.1 16.8 84.2 136.5 12.2 50.7 57.5 3.3 39.7 42.2 37.4 38.4 22.0 370.3 14.4 145.8 44.7 23.6 181.2 51.1 28.9 26.0 195.2 31.6 9.2 62.8 46.0 108.2 82.5 5.5 37.6 20.1 35.9 5.5 16.5 20.4 167.6 8.4 GPATCH2L "C14orf118, FLJ10033, FLJ20689" ENSG00000089916 "G-patch domain containing 2 like" Q9NWQ4 14 76151916-76254342 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018856 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 15: RT4 - Unknown function" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "HPA018856: AB_1845553" "unprognostic (5.98e-2)" "unprognostic (1.44e-2)" "unprognostic (7.07e-2)" "unprognostic (1.26e-2)" "unprognostic (1.51e-2)" "unprognostic (5.59e-2)" "unprognostic (6.63e-3)" "unprognostic (1.81e-2)" "unprognostic (2.89e-2)" "unprognostic (2.70e-1)" "unprognostic (2.05e-2)" "unprognostic (5.60e-2)" "unprognostic (5.81e-2)" "unprognostic (7.79e-2)" "unprognostic (2.14e-1)" "unprognostic (8.09e-2)" "unprognostic (1.81e-1)" 9.9 8.9 7.5 12.1 10.1 37.5 9.7 10.7 9.7 8.9 11.4 9.9 8.5 10.5 9.5 11.3 8.0 12.2 13.3 7.8 10.2 8.9 6.8 10.7 12.1 9.9 8.9 10.4 8.7 9.2 6.9 11.3 9.4 9.8 10.8 15.5 8.2 9.8 12.1 9.0 9.2 11.9 9.9 10.8 9.3 13.8 8.8 11.6 9.7 14.0 12.1 10.5 9.3 12.8 18.7 24.0 19.2 15.3 11.0 17.0 15.7 21.7 15.0 20.7 20.1 16.0 30.8 22.2 12.6 16.8 16.8 22.0 23.4 14.2 36.6 24.7 12.9 19.5 26.1 10.1 14.2 13.7 27.6 17.6 12.6 17.8 23.0 16.2 21.9 18.1 20.6 30.6 18.6 30.6 18.3 17.7 24.2 11.1 17.5 20.3 23.2 11.5 14.7 37.0 15.5 19.2 24.5 21.6 12.0 19.7 25.2 21.2 24.0 26.7 15.3 14.9 16.5 30.7 31.3 29.2 21.4 18.4 28.0 5.3 7.3 7.9 3.5 6.6 3.0 6.3 1.9 5.2 7.2 5.3 4.2 3.0 5.6 5.6 4.8 5.6 4.5 3.7 7.5 10.1 10.7 9.7 7.8 10.2 9.9 8.9 9.4 9.9 8.8 12.8 35.3 16.0 18.2 48.0 30.2 23.3 37.4 26.0 22.2 100.0 19.9 21.2 46.3 18.6 25.2 18.4 104.3 16.2 36.8 18.8 3.9 20.0 151.4 28.9 46.2 38.2 47.8 17.1 76.0 13.3 12.7 36.6 21.9 54.5 43.7 48.2 29.3 11.6 25.2 158.2 67.0 19.3 24.4 43.0 48.9 138.9 24.8 43.5 23.2 59.0 47.7 42.3 43.3 82.0 75.0 30.4 29.4 37.6 24.6 56.9 40.2 13.5 24.4 122.7 26.3 55.0 41.7 56.6 27.2 18.7 27.3 17.4 31.2 34.9 20.6 42.6 GPHN KIAA1385 ENSG00000171723 Gephyrin Q9NQX3 14 66507407-67181803 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" "Multifunctional enzyme, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 62.4" "Group enriched" "Detected in many" 4 "Astrocytes: 493.0;Excitatory neurons: 686.5;Inhibitory neurons: 866.7;Oligodendrocyte precursor cells: 576.1;Oligodendrocytes: 597.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003116, CAB004419, HPA024694" Enhanced Approved Vesicles,Cytosol NA NA 6900 "Cluster 16: MAIT-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Cytosol "CAB004419: AB_627670, HPA003116: AB_1078963, HPA024694: AB_1849616" "unprognostic (8.37e-2)" "unprognostic (2.53e-2)" "unprognostic (2.42e-1)" "unprognostic (1.20e-1)" "unprognostic (5.14e-2)" "unprognostic (4.89e-3)" "unprognostic (8.29e-2)" "unprognostic (1.41e-2)" "unprognostic (1.42e-1)" "unprognostic (2.23e-1)" "unprognostic (2.49e-2)" "unprognostic (8.54e-2)" "prognostic favorable (5.25e-12)" "unprognostic (9.81e-2)" "unprognostic (2.27e-1)" "unprognostic (7.50e-2)" "prognostic unfavorable (4.61e-5)" 13.8 11.1 35.5 3.5 36.0 2.6 13.4 48.4 54.1 9.7 20.9 11.8 7.4 9.9 11.6 12.2 11.1 6.2 17.1 36.1 37.6 25.3 62.4 9.3 3.8 32.7 35.3 8.9 23.9 11.7 13.6 3.6 32.3 11.3 10.1 23.1 9.4 6.6 24.5 15.2 9.0 6.2 32.4 6.7 14.7 6.2 34.6 5.8 11.9 13.8 4.3 11.4 10.7 39.5 39.9 8.8 13.7 15.9 14.2 17.5 9.5 11.1 5.7 12.7 12.2 2.8 17.9 0.0 1.8 7.7 5.5 13.1 17.0 19.9 18.9 15.0 14.9 15.8 9.4 22.3 7.8 9.1 15.8 13.3 13.8 2.9 16.0 4.8 11.8 13.8 9.3 14.2 7.1 19.2 11.9 22.2 5.0 28.3 17.0 0.0 32.5 13.2 16.7 7.5 25.8 10.3 10.2 31.6 12.4 3.3 18.5 11.5 6.7 14.1 24.8 11.3 13.0 22.8 9.1 0.3 10.5 0.8 11.2 0.0 0.7 0.3 2.0 1.2 3.2 1.2 2.5 1.7 1.1 1.9 1.7 1.6 0.0 1.3 1.0 1.5 3.0 0.7 35.5 36.0 48.4 54.1 36.1 37.6 32.7 35.3 32.3 32.4 34.6 39.5 11.5 6.4 13.1 493.0 11.8 4.7 9.2 5.8 27.9 34.3 12.4 6.7 12.7 8.6 10.8 1.8 52.1 3.9 3.5 8.6 13.7 4.0 3.8 7.2 13.5 10.7 6.0 7.6 686.5 5.3 2.3 8.7 19.9 13.6 0.0 3.9 15.7 47.6 3.7 43.7 866.7 15.0 8.2 5.8 1.7 5.0 11.1 4.5 1.8 148.0 1.3 8.9 1.0 576.1 597.5 3.1 7.8 5.7 15.1 11.5 7.1 20.1 2.4 34.9 0.0 12.5 11.8 11.8 8.9 26.7 5.8 2.1 7.9 9.0 10.4 6.5 GPM6A GPM6 ENSG00000150625 "Glycoprotein M6A" P51674 4 175632934-176002664 "Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "brain: 577.8;choroid plexus: 249.3;retina: 147.3" "Cell type enhanced" "Detected in many" "Astrocytes: 3712.4;Excitatory neurons: 833.0;Inhibitory neurons: 581.3;Muller glia cells: 459.6;Oligodendrocyte precursor cells: 1341.6" "Cancer enriched" "Detected in many" 107 "glioma: 110.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "memory B-cell: 34.8;naive B-cell: 16.6" "Lineage enriched" "Detected in many" 12 "B-cells: 34.8" "Group enriched" "Detected in some" 10 "AF22: 49.9;Daudi: 43.0;HAP1: 17.4;U-251 MG: 50.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017338 Supported NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA017338: AB_1849933" "unprognostic (1.36e-4)" "unprognostic (3.35e-3)" "unprognostic (2.96e-2)" "unprognostic (1.34e-2)" "unprognostic (9.45e-2)" "unprognostic (1.34e-1)" "unprognostic (3.82e-5)" "unprognostic (2.24e-1)" "unprognostic (9.13e-3)" "unprognostic (1.06e-1)" "unprognostic (3.69e-2)" "unprognostic (7.73e-2)" "unprognostic (2.24e-2)" "unprognostic (3.53e-2)" "unprognostic (1.45e-1)" "unprognostic (1.36e-3)" "unprognostic (2.60e-3)" 3.8 4.2 366.9 1.4 455.6 0.5 2.5 422.6 577.8 6.8 249.3 25.4 1.9 7.7 2.9 1.9 7.5 4.4 2.8 469.8 268.7 7.1 13.4 20.1 2.6 225.0 265.4 12.3 1.8 0.7 7.7 0.3 222.4 5.7 6.0 147.3 0.9 6.9 0.6 0.8 3.4 11.1 257.9 15.8 1.1 1.5 281.9 0.3 11.9 0.6 1.3 2.6 2.9 336.4 0.3 0.7 49.9 0.5 0.0 0.0 0.2 0.1 0.5 0.2 0.4 1.1 0.7 43.0 0.2 0.2 1.8 0.9 17.4 1.5 0.1 0.2 4.0 0.5 3.7 1.4 0.1 0.4 0.7 0.1 0.0 0.1 0.2 2.0 0.0 0.1 0.4 1.7 0.0 1.2 1.6 0.6 1.2 0.0 0.6 0.2 0.2 0.3 0.1 2.1 0.5 0.4 0.2 0.9 0.2 0.3 0.6 0.1 0.2 0.9 0.6 0.6 50.8 1.6 0.1 2.6 1.8 0.4 1.1 0.8 0.1 0.1 0.1 0.1 0.1 34.8 0.1 0.0 0.2 16.6 0.1 0.1 0.4 0.1 0.2 2.9 0.1 0.8 366.9 455.6 422.6 577.8 469.8 268.7 225.0 265.4 222.4 257.9 281.9 336.4 0.6 96.1 8.7 3712.4 9.6 1.8 5.3 0.0 0.0 220.3 0.2 0.1 0.7 1.5 0.6 0.0 14.6 0.0 0.0 0.1 1.9 0.0 11.7 0.4 0.1 29.0 0.0 5.3 833.0 0.2 0.2 2.4 0.0 0.2 0.0 0.2 116.0 2.1 0.3 124.5 581.3 0.0 0.0 4.4 0.4 3.6 3.4 1.6 0.0 208.0 0.0 459.6 0.0 1341.6 37.3 0.0 0.0 1.5 0.1 9.0 0.0 3.4 0.0 30.5 0.0 15.3 3.3 0.5 0.4 0.2 0.9 0.1 1.2 3.0 0.0 6.5 GPN3 "ATPBD1C, MGC14560" ENSG00000111231 "GPN-loop GTPase 3" Q9UHW5 12 110452486-110469268 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 187.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039764, HPA047793" Uncertain Approved "Nuclear speckles,Cytosol" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" Cytosol "HPA039764: AB_2676669, HPA047793: AB_2680157" "unprognostic (1.68e-3)" "unprognostic (1.11e-2)" "unprognostic (9.82e-2)" "unprognostic (4.96e-2)" "unprognostic (2.09e-1)" "unprognostic (3.27e-3)" "prognostic unfavorable (3.98e-5)" "unprognostic (5.50e-2)" "unprognostic (4.45e-2)" "unprognostic (2.70e-1)" "unprognostic (1.24e-1)" "unprognostic (3.56e-2)" "prognostic favorable (2.65e-6)" "unprognostic (5.81e-2)" "unprognostic (2.85e-1)" "unprognostic (1.62e-1)" "unprognostic (2.27e-1)" 25.6 18.9 10.4 16.3 11.7 15.4 24.4 12.9 12.9 15.7 11.6 15.6 8.1 17.8 15.2 16.3 18.5 13.8 34.2 10.0 11.0 31.4 32.1 16.9 22.9 12.2 11.2 23.3 19.9 29.2 11.1 21.3 12.8 22.2 13.1 23.4 24.2 18.0 47.9 11.1 10.6 19.5 13.0 16.2 15.6 41.3 10.9 18.1 21.2 51.1 18.1 17.6 13.8 14.9 42.3 65.8 43.2 42.8 47.5 30.1 57.6 57.1 34.1 62.2 50.3 59.7 24.6 81.5 38.5 31.0 46.0 37.9 54.2 50.5 83.9 46.9 50.6 47.7 33.8 50.5 33.2 75.2 42.2 32.2 31.4 61.1 39.5 34.9 45.6 67.0 82.1 17.9 44.3 28.2 69.8 142.8 53.4 58.6 64.8 23.5 59.9 62.2 39.3 37.8 34.7 34.8 57.7 39.0 49.9 55.0 66.7 87.7 25.4 51.6 38.0 51.3 66.6 24.7 68.0 85.1 38.2 68.5 60.3 41.0 54.4 79.4 30.0 71.9 32.8 46.5 32.0 34.2 51.1 47.9 40.5 26.9 27.4 28.4 75.3 62.5 30.1 41.6 10.4 11.7 12.9 12.9 10.0 11.0 12.2 11.2 12.8 13.0 10.9 14.9 23.8 25.6 34.5 3.3 24.5 29.8 49.3 57.9 15.9 18.8 28.8 32.5 43.8 20.0 36.0 33.1 14.6 62.4 26.6 3.8 107.6 30.4 111.1 24.9 24.6 20.8 8.3 26.9 4.3 21.3 74.0 25.4 8.2 21.5 31.0 18.6 18.2 38.1 94.7 21.9 5.6 9.1 40.7 19.1 17.7 22.6 19.9 33.2 16.0 14.0 39.6 25.7 19.6 3.5 6.4 22.4 11.0 23.7 20.9 55.5 5.3 72.1 34.2 33.0 26.3 31.0 35.3 187.2 77.6 20.8 25.4 46.7 19.2 22.1 13.7 40.2 GPR160 "GPCR1, GPCR150" ENSG00000173890 "G protein-coupled receptor 160" Q9UJ42 3 170037995-170085392 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 107.9;parathyroid gland: 216.6" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 194.8;Proximal enterocytes: 362.1;Proximal tubular cells: 151.4;Rod photoreceptor cells: 153.2;Undifferentiated cells: 199.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 123.9;SK-BR-3: 95.8;THP-1: 197.2;U-266/70: 206.2;U-266/84: 127.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006970 Approved Supported "Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA006970: AB_1849275" "unprognostic (1.70e-1)" "unprognostic (5.08e-3)" "unprognostic (2.96e-2)" "unprognostic (2.39e-3)" "unprognostic (2.20e-1)" "unprognostic (3.01e-1)" "unprognostic (5.21e-2)" "prognostic favorable (1.21e-4)" "unprognostic (5.71e-3)" "unprognostic (1.35e-1)" "unprognostic (4.35e-2)" "unprognostic (1.77e-1)" "prognostic favorable (4.93e-7)" "unprognostic (1.40e-1)" "unprognostic (2.25e-1)" "unprognostic (1.43e-1)" "prognostic favorable (3.61e-4)" 12.2 1.7 0.7 15.9 1.0 107.9 22.5 1.0 1.6 11.2 0.9 72.0 73.8 5.8 57.9 2.9 5.4 18.6 1.0 0.6 0.7 59.8 4.1 15.0 27.9 1.4 0.9 0.6 18.4 216.6 1.4 4.1 1.1 26.7 72.6 104.7 19.3 6.3 1.3 1.2 98.6 4.4 0.8 25.2 43.0 5.2 0.9 9.5 6.7 2.7 30.4 26.8 1.0 1.2 64.2 1.5 0.3 0.5 0.3 0.4 15.6 0.4 0.5 0.4 1.9 11.7 8.1 29.4 12.9 0.6 4.0 0.7 8.8 0.5 1.0 45.9 17.7 19.1 1.0 24.3 0.2 38.2 24.8 0.2 0.9 2.0 2.3 2.8 1.4 13.7 6.4 73.9 0.4 41.5 2.9 8.4 10.3 39.1 2.4 5.3 1.1 123.9 32.3 86.8 6.1 1.8 0.8 95.8 4.5 8.2 55.9 197.2 1.9 0.2 0.4 7.1 4.8 206.2 127.9 51.4 0.8 40.3 2.8 2.9 1.1 9.3 0.5 0.4 1.0 8.0 1.0 0.4 2.4 12.3 3.0 1.1 11.3 0.4 0.2 3.2 0.3 1.2 0.7 1.0 1.0 1.6 0.6 0.7 1.4 0.9 1.1 0.8 0.9 1.2 35.2 9.6 51.1 0.7 25.9 0.4 3.2 4.1 0.0 9.5 48.5 18.3 1.0 28.6 22.7 62.5 39.6 3.1 11.6 88.9 54.8 10.3 33.7 20.6 4.4 8.7 194.8 0.4 1.5 72.0 21.1 1.0 50.0 54.0 1.3 0.1 20.0 0.9 7.4 15.2 0.6 133.9 18.3 11.7 11.2 36.3 0.6 17.0 28.4 7.5 62.3 16.6 0.0 1.0 0.9 60.3 118.6 0.4 56.8 25.4 362.1 151.4 27.9 153.2 0.0 0.8 1.4 7.4 13.1 0.9 0.9 27.2 4.2 1.2 199.7 35.5 GPR171 H963 ENSG00000174946 "G protein-coupled receptor 171" O14626 3 151197832-151203216 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 21.3" "Cell type enriched" "Detected in some" 4 "T-cells: 107.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 110.3" "Lineage enriched" "Detected in many" 15 "T-cells: 110.3" "Cell line enriched" "Detected in some" 25 "U-266/70: 27.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA067323 Supported NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA067323: " "unprognostic (6.82e-6)" "unprognostic (4.90e-3)" "unprognostic (7.10e-2)" "unprognostic (6.85e-4)" "unprognostic (2.80e-3)" "unprognostic (1.04e-3)" "unprognostic (4.19e-4)" "unprognostic (6.09e-2)" "unprognostic (4.93e-3)" "unprognostic (1.01e-3)" "unprognostic (8.84e-2)" "unprognostic (1.08e-1)" "unprognostic (4.72e-6)" "unprognostic (1.31e-1)" "unprognostic (4.17e-2)" "unprognostic (4.58e-2)" "unprognostic (1.02e-2)" 3.7 1.6 0.5 21.3 1.5 1.2 1.9 1.7 3.8 4.3 12.3 4.3 4.5 1.5 0.5 2.5 3.0 6.2 0.9 1.1 0.4 1.3 4.3 6.4 17.4 2.5 0.7 0.8 0.7 0.2 0.5 0.5 0.7 1.9 4.6 0.0 1.7 0.8 0.2 0.9 12.9 1.1 0.1 13.0 5.9 0.3 1.1 13.0 1.8 0.1 11.3 9.3 2.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.2 0.1 0.0 0.0 0.2 0.0 0.2 0.3 3.5 27.9 0.2 110.3 0.0 40.2 53.5 2.3 0.5 24.1 21.1 0.8 7.3 0.5 2.2 21.4 9.4 0.5 1.5 1.7 3.8 1.1 0.4 2.5 0.7 0.7 0.1 1.1 1.2 0.4 0.0 2.2 0.3 2.3 1.1 0.4 0.0 0.6 4.8 0.3 0.3 1.0 0.0 1.3 0.0 2.1 0.4 25.8 0.1 0.0 0.0 0.2 0.1 0.6 0.5 0.0 2.7 0.8 0.0 0.0 2.3 4.6 0.1 2.5 0.0 1.8 1.6 0.1 21.9 0.3 0.5 0.0 2.2 8.1 0.1 0.0 4.8 0.0 0.0 14.0 5.7 6.2 0.5 0.0 0.0 0.0 0.0 14.9 0.2 0.0 0.5 0.0 0.1 0.0 0.5 1.2 0.8 0.7 0.1 0.6 0.7 107.6 0.1 0.0 0.3 GPR3 ACCA ENSG00000181773 "G protein-coupled receptor 3" P46089 1 27392622-27395814 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.8;heart muscle: 5.4" "Cell type enhanced" "Detected in some" "Adipocytes: 5.5;Basal squamous epithelial cells: 2.8;Cardiomyocytes: 2.8;Enteroendocrine cells: 4.8;Horizontal cells: 5.0;Inhibitory neurons: 4.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-2197: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB006254 Uncertain NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "CAB006254: AB_425462" "unprognostic (4.42e-2)" "unprognostic (2.22e-1)" "unprognostic (4.05e-2)" "unprognostic (1.55e-2)" "unprognostic (1.38e-2)" "unprognostic (1.27e-1)" "unprognostic (7.30e-3)" "unprognostic (6.87e-2)" "unprognostic (2.97e-1)" "unprognostic (1.09e-1)" "unprognostic (5.94e-2)" "unprognostic (1.97e-1)" "unprognostic (1.46e-1)" "unprognostic (8.17e-2)" "unprognostic (2.07e-2)" "unprognostic (6.54e-2)" "unprognostic (1.03e-2)" 1.9 0.6 1.5 0.7 1.7 1.0 1.3 4.2 7.8 0.6 0.4 0.7 0.2 0.5 0.0 0.5 0.8 0.7 5.4 2.2 3.1 1.5 0.4 2.2 0.2 4.0 3.1 0.4 0.6 0.5 4.4 0.4 3.9 0.9 0.2 1.5 0.5 0.1 0.5 0.6 0.5 0.6 2.5 0.2 0.8 0.2 2.2 0.2 1.8 1.5 0.1 0.8 0.4 2.5 1.9 1.0 5.3 5.9 0.2 0.6 0.7 3.4 4.0 5.2 3.8 1.6 1.1 0.3 0.8 1.6 5.3 1.3 1.4 4.2 4.0 0.1 0.2 1.5 0.3 3.4 0.6 3.4 4.5 0.7 0.0 7.3 1.6 0.5 1.6 2.3 4.3 5.8 6.4 2.7 0.7 4.8 7.8 2.7 8.4 9.2 4.2 2.5 2.2 0.4 1.0 2.5 1.7 0.7 6.6 2.2 0.1 0.7 1.0 3.9 7.1 23.0 4.2 0.7 4.3 0.5 5.9 1.1 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.7 4.2 7.8 2.2 3.1 4.0 3.1 3.9 2.5 2.2 2.5 5.5 0.0 0.0 0.7 0.1 0.1 2.3 1.0 2.8 1.6 0.7 0.5 2.8 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.1 0.6 0.3 1.4 4.8 0.0 2.6 0.0 0.3 1.4 1.1 0.6 0.0 0.0 0.0 0.0 0.2 5.0 4.6 0.2 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 2.0 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.1 0.0 1.7 1.0 0.0 0.1 0.7 0.0 0.1 0.1 0.1 0.5 0.4 GPR34 ENSG00000171659 "G protein-coupled receptor 34" Q9UPC5 X 41688973-41697275 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 42.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 251.4;Kupffer cells: 173.3;Macrophages: 100.6;Microglial cells: 54.4" "Cancer enhanced" "Detected in all" "glioma: 26.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "basophil: 339.6;eosinophil: 117.9" "Lineage enriched" "Detected in many" 24 "granulocytes: 339.6" "Cell line enhanced" "Detected in single" "HMC-1: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010668, CAB025490" Uncertain Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB025490: , HPA010668: AB_1849294" "unprognostic (1.26e-2)" "unprognostic (1.08e-1)" "unprognostic (1.43e-2)" "unprognostic (1.44e-2)" "unprognostic (1.20e-1)" "unprognostic (3.74e-2)" "unprognostic (5.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.59e-2)" "unprognostic (9.81e-3)" "unprognostic (7.19e-2)" "unprognostic (1.74e-1)" "unprognostic (3.96e-1)" "unprognostic (2.72e-3)" "unprognostic (1.14e-1)" "unprognostic (1.88e-3)" "unprognostic (3.18e-2)" 28.2 17.1 5.2 15.1 5.2 0.9 21.5 6.1 5.8 14.0 5.6 12.0 6.5 6.7 2.7 8.2 7.8 17.0 8.3 5.0 7.6 5.0 8.5 10.9 20.0 10.6 7.9 7.3 5.4 5.3 1.4 42.7 11.4 3.2 13.1 0.6 3.6 8.8 0.8 1.0 14.6 16.3 9.9 15.6 7.8 2.7 9.7 6.9 3.7 4.6 16.7 13.3 1.7 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 339.6 9.7 117.9 0.0 12.9 0.4 1.5 0.4 0.1 2.0 1.2 0.1 0.3 1.1 14.3 7.0 0.3 0.6 2.8 5.2 5.2 6.1 5.8 5.0 7.6 10.6 7.9 11.4 9.9 9.7 18.8 0.9 0.0 2.8 1.0 2.0 0.6 0.2 0.0 0.0 0.0 0.5 2.3 1.2 0.0 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.0 0.6 0.1 0.1 5.0 1.2 0.4 0.7 0.0 1.6 1.0 0.5 0.0 37.3 0.0 2.9 0.8 251.4 0.0 0.9 0.0 0.0 173.3 13.6 1.9 0.9 100.6 1.8 54.4 7.1 0.1 1.0 3.5 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.1 0.0 0.8 19.7 0.6 0.3 0.0 0.2 0.4 1.0 2.5 7.2 0.1 0.1 0.0 GPR37 "EDNRBL, hET(B)R-LP, PAELR" ENSG00000170775 "G protein-coupled receptor 37" O15354 7 124743885-124765792 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 109.5;retina: 39.0" "Group enriched" "Detected in many" 8 "Muller glia cells: 616.6;Oligodendrocytes: 324.9" "Group enriched" "Detected in many" 4 "glioma: 19.2;liver cancer: 5.7;melanoma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 7.5;fHDF/TERT166: 17.7;hTCEpi: 7.7;SK-BR-3: 6.8;SuSa: 8.0;TIME: 12.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042903, HPA068009" Approved Approved "Nuclear membrane,Cytosol" No No 900000 "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "Nuclear membrane, Cytosol" "HPA042903: AB_2678219, HPA068009: AB_2685940" "unprognostic (2.47e-1)" "unprognostic (2.57e-1)" "unprognostic (2.46e-1)" "unprognostic (3.30e-2)" "unprognostic (7.29e-2)" "unprognostic (1.06e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (6.00e-5)" "unprognostic (6.19e-2)" "prognostic favorable (7.26e-4)" "unprognostic (6.54e-2)" "unprognostic (2.58e-1)" "unprognostic (3.16e-2)" "unprognostic (6.12e-3)" "unprognostic (2.10e-1)" "unprognostic (1.88e-1)" "unprognostic (1.71e-4)" 0.5 0.1 28.3 0.1 65.3 0.0 0.5 53.8 43.4 0.3 5.2 0.6 0.0 1.6 0.2 3.7 0.6 0.2 0.1 31.2 40.4 0.3 10.0 0.2 0.1 62.8 56.3 0.0 1.5 0.1 0.2 5.1 62.5 0.5 0.3 39.0 0.9 0.5 0.6 2.3 0.6 1.2 45.2 2.1 1.3 10.6 47.8 0.0 0.0 0.1 0.0 1.4 0.6 109.5 0.1 1.4 7.5 0.0 0.0 0.0 2.1 0.5 1.9 1.9 0.4 0.3 0.7 0.0 0.0 17.7 0.2 0.1 2.2 0.0 0.4 0.3 1.0 0.1 4.4 0.0 2.2 0.0 0.3 0.0 7.7 0.0 0.1 0.0 3.6 0.0 0.0 3.4 0.0 0.4 0.0 0.0 1.1 0.0 3.5 0.0 0.0 0.0 0.0 0.1 1.7 2.7 0.0 6.8 2.6 8.0 1.7 0.0 12.7 1.5 0.6 0.0 0.0 1.1 0.0 0.0 0.7 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.3 65.3 53.8 43.4 31.2 40.4 62.8 56.3 62.5 45.2 47.8 109.5 0.1 0.0 0.0 5.9 0.0 4.6 0.5 4.4 6.8 55.8 4.6 3.0 0.6 7.2 1.8 1.8 6.2 10.1 0.0 0.1 0.0 5.1 0.4 2.0 0.4 0.7 0.0 0.0 6.0 0.6 19.7 1.9 0.0 3.4 0.0 0.3 0.4 22.4 1.2 18.5 1.1 1.1 2.0 0.3 0.7 1.7 2.8 0.2 3.6 1.0 0.6 616.6 0.0 1.5 324.9 0.4 0.2 0.7 0.0 3.2 0.0 0.0 1.4 22.5 0.0 4.8 0.7 0.6 2.2 4.6 10.2 3.0 0.5 0.1 0.0 0.4 GPR4 ENSG00000177464 "G protein-coupled receptor 4" P46093 19 45589764-45602212 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 40.6" "Cell type enhanced" "Detected in some" "Adipocytes: 26.7;Endothelial cells: 26.4;Hepatic stellate cells: 24.7;Sertoli cells: 6.6;Smooth muscle cells: 16.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "HUVEC TERT2: 18.7;TIME: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014278 Uncertain NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "HPA014278: AB_1849300" "unprognostic (2.49e-2)" "unprognostic (6.62e-3)" "unprognostic (1.33e-2)" "unprognostic (2.93e-2)" "unprognostic (2.70e-1)" "unprognostic (1.31e-1)" "unprognostic (4.95e-2)" "prognostic unfavorable (9.19e-4)" "unprognostic (1.29e-1)" "unprognostic (6.23e-2)" "unprognostic (1.70e-1)" "unprognostic (4.66e-2)" "prognostic unfavorable (2.07e-5)" "unprognostic (6.46e-3)" "unprognostic (1.93e-1)" "unprognostic (9.18e-2)" "unprognostic (2.49e-3)" 40.6 6.9 7.0 3.3 6.2 0.5 22.1 6.0 8.8 4.9 6.2 4.2 0.9 7.4 0.7 2.6 6.0 3.3 23.8 5.6 5.9 24.6 3.6 28.6 0.9 8.0 7.5 3.5 3.7 1.4 5.9 4.0 8.6 5.8 0.7 0.9 2.9 0.9 5.7 2.9 5.1 2.5 6.5 4.1 5.6 1.7 10.7 0.5 18.2 2.5 0.6 7.0 4.9 6.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.7 0.7 1.1 0.0 0.1 0.0 2.0 0.1 0.0 0.1 0.0 0.1 1.3 0.2 0.1 0.0 0.1 0.0 0.5 0.0 0.8 0.0 0.0 0.3 0.3 0.0 18.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 31.3 0.1 1.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 6.2 6.0 8.8 5.6 5.9 8.0 7.5 8.6 6.5 10.7 6.3 26.7 0.0 0.5 0.7 0.1 2.4 0.2 0.0 1.2 0.1 0.1 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.1 0.3 26.4 0.0 0.0 0.1 0.0 0.0 1.5 2.0 0.2 0.0 0.0 24.7 0.1 0.3 0.0 0.2 0.0 0.0 1.2 1.6 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.7 6.6 0.6 16.8 0.0 0.2 0.1 1.3 0.0 0.1 0.3 0.0 0.3 GPR82 ENSG00000171657 "G protein-coupled receptor 82" Q96P67 X 41724181-41730130 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.7;lymphoid tissue: 6.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 16.5;Cone photoreceptor cells: 20.9;Kupffer cells: 37.0;Rod photoreceptor cells: 17.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 10 "eosinophil: 40.2;NK-cell: 10.9" "Group enriched" "Detected in many" 10 "granulocytes: 40.2;NK-cells: 10.9" "Cell line enriched" "Detected in single" 30 "HMC-1: 4.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA035914 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA035914: AB_10670671" "unprognostic (5.62e-3)" "unprognostic (1.81e-2)" "unprognostic (4.65e-2)" "unprognostic (3.88e-3)" "unprognostic (1.15e-2)" "unprognostic (3.28e-2)" "unprognostic (4.62e-4)" "unprognostic (1.41e-3)" "unprognostic (2.12e-2)" "unprognostic (5.00e-2)" "unprognostic (1.39e-1)" "unprognostic (3.01e-1)" "unprognostic (7.45e-2)" "unprognostic (2.37e-2)" "unprognostic (2.26e-1)" "unprognostic (8.00e-3)" "unprognostic (1.18e-1)" 0.1 0.9 0.7 2.3 0.5 0.1 0.6 0.8 0.7 0.3 0.4 1.1 1.7 0.3 0.1 0.4 0.3 0.6 0.1 0.5 1.0 0.3 0.7 0.2 3.2 1.4 0.7 0.2 0.1 0.2 0.1 0.0 0.7 0.2 1.1 0.0 0.4 0.4 0.0 0.4 2.7 0.3 0.6 1.1 0.9 0.0 1.3 0.5 0.3 0.0 6.9 0.8 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.4 40.2 0.0 2.5 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.3 10.9 2.4 0.0 0.0 0.2 0.7 0.5 0.8 0.7 0.5 1.0 1.4 0.7 0.7 0.6 1.3 0.8 0.7 0.0 7.2 2.0 5.5 4.7 5.2 2.8 0.6 16.5 1.2 0.3 0.4 4.3 5.9 1.8 20.9 0.9 3.7 3.1 0.0 2.0 0.2 1.0 3.4 3.1 1.2 0.8 1.7 1.1 0.2 2.9 1.5 1.4 0.0 1.4 3.3 1.3 1.3 13.5 2.2 2.0 2.0 37.0 7.7 0.2 4.1 13.9 3.6 0.0 3.4 1.7 12.3 10.6 1.1 2.8 5.1 3.0 1.3 3.6 6.9 0.3 1.1 17.2 0.0 3.4 2.3 1.6 1.1 0.3 2.7 0.7 12.6 3.9 3.4 3.8 GPR85 SREB2 ENSG00000164604 "G protein-coupled receptor 85" P60893 7 113078331-113087778 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 39.1;choroid plexus: 19.8;retina: 12.1;skeletal muscle: 31.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 36.7;Early spermatids: 183.6;Horizontal cells: 84.1;Microglial cells: 40.3" "Cancer enhanced" "Detected in some" "glioma: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "HEL: 107.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 36: HEL - Hemostasis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (3.80e-2)" "unprognostic (1.93e-2)" "unprognostic (6.98e-3)" "unprognostic (3.92e-2)" "unprognostic (2.68e-2)" "unprognostic (2.41e-2)" "unprognostic (9.90e-2)" "unprognostic (1.94e-1)" "unprognostic (6.09e-2)" "unprognostic (1.54e-1)" "unprognostic (1.08e-1)" "unprognostic (1.68e-1)" "unprognostic (1.34e-5)" "unprognostic (5.89e-3)" "unprognostic (9.99e-2)" "unprognostic (1.69e-1)" "unprognostic (1.23e-2)" 1.7 0.7 28.4 0.9 28.7 1.6 0.6 28.0 39.1 0.4 19.8 0.5 0.7 0.7 0.6 0.4 1.4 3.8 2.5 30.5 25.3 0.7 4.2 2.0 1.3 26.6 25.4 0.2 1.3 1.1 2.1 4.7 26.5 0.8 0.3 12.1 2.5 0.5 31.9 0.5 0.7 0.8 25.7 3.6 0.6 3.1 27.6 0.3 0.6 0.2 0.6 1.9 0.3 27.3 0.2 0.2 0.6 0.6 2.1 3.1 0.6 2.8 4.2 5.7 7.4 0.1 0.9 0.3 0.7 2.5 1.8 0.5 0.6 2.5 12.1 0.4 0.3 107.7 1.2 0.3 1.0 19.7 0.7 4.1 0.6 9.9 0.2 0.2 0.3 0.8 0.5 0.9 6.8 0.3 2.0 13.1 1.2 0.1 0.5 0.5 1.3 0.5 0.1 1.3 2.8 2.3 0.2 1.4 1.0 0.6 0.6 4.6 0.3 6.3 0.9 1.7 2.5 2.2 0.3 1.2 7.6 7.5 2.6 0.6 0.2 0.2 0.1 0.4 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.3 0.2 0.4 0.1 0.1 0.1 28.4 28.7 28.0 39.1 30.5 25.3 26.6 25.4 26.5 25.7 27.6 27.3 2.0 0.0 1.5 1.3 0.3 8.8 13.9 0.4 1.8 36.7 3.6 2.5 3.9 0.0 0.7 0.0 0.0 0.2 0.2 0.0 0.0 0.1 183.6 0.9 1.7 14.1 0.0 0.0 9.1 0.2 0.9 3.4 0.0 0.8 1.3 0.6 0.4 0.2 13.2 84.1 6.5 0.2 0.0 7.2 11.3 21.0 1.2 2.8 10.6 40.3 0.3 1.6 1.0 6.6 1.0 0.1 0.0 0.4 0.0 14.8 0.0 0.3 0.6 4.3 0.0 14.4 4.4 5.3 0.5 0.1 10.5 0.4 1.8 0.7 0.0 10.3 GPRASP2 "FLJ37327, GASP2" ENSG00000158301 "G protein-coupled receptor associated sorting protein 2" Q96D09 X 102712176-102717733 "Disease related genes, Predicted intracellular proteins" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 19.6;Cardiomyocytes: 16.4;Horizontal cells: 16.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.4" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017438 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol Nucleoplasm "HPA017438: AB_1849504" "unprognostic (8.74e-3)" "unprognostic (1.99e-1)" "unprognostic (2.47e-2)" "unprognostic (5.14e-3)" "unprognostic (4.60e-2)" "unprognostic (5.06e-2)" "unprognostic (1.12e-1)" "unprognostic (1.89e-2)" "unprognostic (2.99e-1)" "unprognostic (1.06e-1)" "prognostic favorable (5.71e-4)" "unprognostic (1.42e-1)" "prognostic favorable (4.60e-6)" "unprognostic (1.19e-2)" "unprognostic (9.03e-2)" "unprognostic (8.05e-2)" "prognostic unfavorable (6.63e-5)" 5.1 15.0 19.1 2.1 18.9 0.4 7.8 10.6 22.3 13.6 6.7 7.5 1.7 17.7 9.0 4.2 10.7 5.1 14.5 18.6 31.4 10.2 6.8 5.0 1.8 13.8 15.0 30.1 9.3 14.9 20.0 3.7 15.8 12.5 3.1 12.7 9.2 11.8 7.5 5.8 3.2 10.3 12.8 4.2 4.0 4.7 24.8 4.5 15.2 6.5 1.7 6.4 6.5 13.4 0.6 6.8 17.8 13.8 5.5 6.5 1.3 10.3 9.3 8.7 16.9 2.3 3.1 0.0 3.5 10.8 4.3 2.4 21.5 5.6 11.0 0.0 8.3 0.9 2.0 0.5 4.0 1.7 1.2 6.9 5.8 9.7 0.4 10.1 6.2 1.7 2.7 0.7 10.6 3.2 4.9 0.7 8.9 2.2 9.3 6.4 2.9 0.0 5.4 2.5 3.9 12.2 10.4 2.0 1.5 5.4 5.7 3.6 5.6 6.1 12.9 12.5 9.9 0.3 0.4 0.0 8.2 1.1 3.5 0.0 0.1 0.0 0.2 0.2 0.2 0.1 0.3 0.4 0.2 0.1 1.4 0.6 0.0 0.8 0.0 0.5 0.5 0.4 19.1 18.9 10.6 22.3 18.6 31.4 13.8 15.0 15.8 12.8 24.8 13.4 4.3 0.0 1.5 0.0 0.5 2.3 5.1 2.1 4.0 19.6 3.5 4.1 16.4 7.2 3.6 5.5 2.1 6.2 0.3 0.6 9.8 1.6 0.5 0.7 4.1 4.3 3.0 0.0 0.0 0.9 0.5 6.6 0.0 0.6 0.0 13.2 8.2 7.3 0.9 16.8 0.0 1.4 2.0 0.6 0.8 1.1 12.2 0.6 0.0 0.0 0.5 12.2 0.0 0.0 0.0 1.1 1.8 12.4 0.0 3.2 0.3 10.8 0.8 6.8 6.6 8.9 4.9 13.4 9.1 2.4 3.0 2.2 0.7 8.0 1.1 1.5 GPX8 "EPLA847, UNQ847" ENSG00000164294 "Glutathione peroxidase 8 (putative)" Q8TED1 5 55160167-55167297 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 62.7;Extravillous trophoblasts: 218.9;Fibroblasts: 76.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 254.4;fHDF/TERT166: 246.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036720 Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "Actin filaments" "HPA036720: AB_2675269" "unprognostic (4.85e-2)" "unprognostic (1.23e-2)" "unprognostic (6.53e-2)" "unprognostic (1.92e-2)" "unprognostic (2.31e-2)" "unprognostic (9.74e-3)" "unprognostic (1.78e-2)" "unprognostic (1.63e-3)" "unprognostic (2.07e-2)" "unprognostic (4.34e-2)" "unprognostic (4.31e-2)" "unprognostic (8.68e-2)" "prognostic unfavorable (5.13e-9)" "prognostic unfavorable (7.96e-4)" "unprognostic (8.11e-2)" "unprognostic (1.16e-2)" "unprognostic (2.63e-2)" 13.3 6.1 1.2 12.5 1.2 0.1 12.6 1.2 1.6 37.1 6.9 7.3 2.9 21.1 21.9 6.2 14.3 17.0 11.2 1.0 1.7 6.5 2.2 6.9 3.8 1.5 1.1 27.3 4.6 9.3 2.4 39.7 1.4 10.2 8.4 1.3 7.2 15.8 1.5 5.0 4.1 27.2 1.5 4.0 5.6 5.6 1.2 1.3 22.3 6.3 3.0 17.8 9.8 3.6 37.2 39.0 75.3 77.0 180.7 223.9 36.6 179.8 254.4 97.0 192.7 3.2 82.1 0.0 199.0 246.4 86.5 28.2 46.0 51.5 131.5 0.5 17.3 2.1 49.1 6.9 64.4 0.0 0.0 157.5 60.8 68.3 35.5 126.5 122.7 0.0 1.1 0.1 137.4 14.4 0.0 0.0 32.6 1.0 42.8 0.1 40.2 0.0 65.9 1.3 0.1 1.4 56.6 4.6 68.0 80.8 56.6 3.4 102.7 63.6 65.6 84.5 102.3 0.1 0.5 0.5 103.0 0.1 118.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 1.2 1.2 1.6 1.0 1.7 1.5 1.1 1.4 1.5 1.2 3.6 10.9 0.0 1.1 0.3 0.3 7.1 6.0 38.3 9.1 0.2 8.9 6.1 4.3 0.0 33.3 25.8 0.0 49.5 0.2 0.5 5.9 13.7 0.4 6.5 62.7 18.6 0.0 0.0 0.1 38.8 218.9 76.6 2.6 4.9 4.5 30.9 19.2 0.2 10.2 0.0 0.1 4.7 4.1 0.0 6.9 0.6 51.3 1.1 24.9 5.6 1.1 7.9 0.0 0.0 0.1 15.8 0.3 39.9 1.4 2.6 0.1 0.5 36.5 0.3 13.1 20.1 38.2 0.1 0.4 3.1 6.1 13.3 1.8 29.9 0.9 2.4 GRAMD1B "KIAA1201, LINC01059" ENSG00000023171 "GRAM domain containing 1B" Q3KR37 11 123358428-123627774 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 258.8;choroid plexus: 91.8;retina: 96.7" "Cell type enhanced" "Detected in many" "Astrocytes: 94.7;Cone photoreceptor cells: 114.7;Excitatory neurons: 120.7;Inhibitory neurons: 102.8;Oligodendrocyte precursor cells: 95.0;Rod photoreceptor cells: 92.3;Theca cells: 109.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 7.0" "Lineage enriched" "Detected in many" 4 "dendritic cells: 7.0" "Group enriched" "Detected in many" 4 "A549: 62.4;HDLM-2: 168.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008557, HPA075204" Approved Supported "Endoplasmic reticulum,Vesicles,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 58: Brain - Synaptic function" "Cluster 44: HDLM-2 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum, Plasma membrane" Vesicles "HPA008557: AB_1079197, HPA075204: " "unprognostic (1.86e-1)" "unprognostic (7.18e-3)" "unprognostic (2.43e-2)" "unprognostic (2.74e-3)" "unprognostic (8.15e-2)" "unprognostic (4.28e-2)" "unprognostic (2.69e-3)" "unprognostic (4.12e-3)" "unprognostic (1.40e-1)" "unprognostic (2.90e-2)" "unprognostic (9.60e-2)" "unprognostic (8.06e-2)" "prognostic unfavorable (4.30e-7)" "unprognostic (1.39e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (1.69e-1)" 1.8 258.8 22.5 4.3 27.4 18.6 1.1 80.1 52.3 0.9 91.8 1.6 34.6 1.1 9.4 0.6 3.6 12.1 15.0 55.6 19.4 15.5 1.5 2.6 5.4 25.7 20.1 15.2 2.4 0.7 16.6 5.0 24.2 1.1 1.1 96.7 1.9 2.0 3.4 0.5 25.2 1.2 9.4 3.6 11.4 16.8 33.5 6.6 4.9 2.2 3.5 1.2 0.8 26.1 0.1 62.4 3.5 0.1 0.3 0.7 9.5 20.5 14.6 4.1 1.8 2.6 0.4 3.8 10.4 10.1 6.8 0.0 6.2 0.0 4.3 168.5 5.0 0.0 28.3 0.7 0.0 22.1 0.0 1.0 0.1 7.1 0.0 5.2 1.8 1.6 0.0 0.2 3.7 0.5 3.8 7.2 7.6 28.3 23.0 10.8 9.8 6.8 0.2 0.0 20.0 16.3 4.9 0.5 0.1 8.1 0.5 12.0 12.3 23.8 3.2 4.2 1.0 0.0 0.0 0.0 4.6 20.5 1.1 0.0 1.2 0.4 0.4 0.7 0.2 0.0 1.5 1.2 1.7 0.0 0.2 0.2 0.1 1.6 0.7 7.0 0.7 0.5 22.5 27.4 80.1 52.3 55.6 19.4 25.7 20.1 24.2 9.4 33.5 26.1 1.4 0.0 0.5 94.7 0.6 0.0 0.0 0.1 1.2 44.3 1.1 1.0 5.7 21.5 0.2 5.5 114.7 6.9 17.9 0.1 3.9 0.7 9.6 1.6 0.6 1.0 0.0 0.0 120.7 0.4 3.7 1.6 16.3 0.9 0.0 41.9 0.7 0.0 2.6 45.4 102.8 1.8 0.0 3.8 2.6 2.7 0.6 7.5 0.0 37.5 2.5 23.4 0.0 95.0 5.5 3.9 1.3 0.7 2.4 0.1 17.3 8.9 0.4 92.3 0.0 3.0 4.2 3.9 1.9 0.1 0.4 2.5 7.2 109.3 1.5 0.0 GRB14 ENSG00000115290 "Growth factor receptor bound protein 14" Q14449 2 164492417-164621482 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 12.6;tongue: 20.3" "Group enriched" "Detected in many" 4 "Distal tubular cells: 92.0;Granulosa cells: 272.4" "Cancer enhanced" "Detected in many" "liver cancer: 9.5" "Region enhanced" "Detected in single" "hippocampal formation: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 5.5;HUVEC TERT2: 9.6;RPTEC TERT1: 9.1;TIME: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB022294, HPA035052, HPA035053" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" "CAB022294: , HPA035052: , HPA035053: AB_2674432" "unprognostic (2.60e-1)" "unprognostic (6.34e-2)" "unprognostic (1.74e-2)" "unprognostic (6.75e-2)" "unprognostic (7.47e-2)" "unprognostic (8.33e-5)" "unprognostic (5.00e-2)" "unprognostic (3.55e-1)" "unprognostic (2.47e-2)" "unprognostic (2.33e-1)" "unprognostic (5.71e-2)" "unprognostic (8.33e-3)" "unprognostic (2.71e-1)" "unprognostic (1.89e-3)" "unprognostic (7.10e-2)" "unprognostic (5.19e-2)" "unprognostic (9.27e-2)" 0.7 3.0 0.0 0.3 0.4 0.0 0.3 0.0 0.6 0.1 0.1 0.9 0.9 0.2 5.4 1.2 0.1 0.1 2.7 1.3 0.1 6.6 12.6 0.4 0.0 0.3 0.2 2.0 4.7 0.0 0.3 1.7 0.0 0.3 0.3 0.4 0.3 0.3 2.4 0.2 0.2 0.4 0.0 0.2 0.2 2.6 0.3 0.0 0.9 20.3 0.0 0.0 0.1 0.0 0.8 5.5 0.3 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 2.5 0.5 0.0 2.9 0.0 0.9 0.3 0.8 1.2 0.3 0.0 4.1 0.0 0.3 1.3 0.1 0.0 0.0 0.3 0.8 1.8 0.0 1.6 9.6 0.0 0.0 0.0 1.5 2.1 0.0 0.0 1.9 0.2 1.2 0.0 0.0 0.1 9.1 0.4 3.1 0.3 0.0 0.3 0.0 1.1 0.7 0.0 11.8 0.1 1.2 0.0 0.1 0.4 0.1 0.0 2.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.6 1.3 0.1 0.3 0.2 0.0 0.0 0.3 0.0 4.5 0.0 5.4 0.7 0.1 0.1 0.3 0.0 0.0 1.3 1.6 1.4 17.7 22.8 0.0 16.5 0.0 0.2 1.3 0.3 92.0 13.5 1.5 0.6 0.2 3.0 0.0 0.0 24.5 3.3 0.2 2.4 0.0 1.9 0.0 272.4 1.1 40.4 0.0 0.0 6.2 2.6 0.0 1.0 0.3 4.4 9.3 3.2 19.6 1.9 1.0 0.3 0.0 3.5 2.3 4.0 0.0 17.3 0.0 0.8 0.3 14.7 0.0 0.8 13.1 0.8 10.9 0.7 6.4 0.1 0.0 0.1 0.2 30.4 1.6 0.2 GREB1 KIAA0575 ENSG00000196208 "Growth regulating estrogen receptor binding 1" Q4ZG55 2 11482341-11642788 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "ovary: 278.3" "Cell type enriched" "Detected in many" 9 "Granulosa cells: 545.2" "Cancer enhanced" "Detected in many" "prostate cancer: 17.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 40.3;Hep G2: 39.6;MCF7: 61.8;SH-SY5Y: 40.5;SK-MEL-30: 30.4;T-47d: 138.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA024616, HPA027843, HPA028416" Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" "Mitochondria, Cytosol" "HPA024616: AB_10599728, HPA027843: AB_10601103, HPA028416: AB_10601344" "unprognostic (1.52e-2)" "unprognostic (4.63e-1)" "unprognostic (1.46e-1)" "prognostic favorable (1.05e-4)" "unprognostic (1.23e-2)" "unprognostic (1.32e-1)" "unprognostic (6.29e-2)" "unprognostic (1.24e-1)" "unprognostic (6.19e-2)" "unprognostic (1.38e-1)" "unprognostic (3.68e-1)" "unprognostic (3.63e-2)" "unprognostic (7.51e-4)" "unprognostic (2.42e-2)" "unprognostic (3.34e-1)" "unprognostic (2.46e-3)" "unprognostic (4.80e-2)" 1.8 3.4 8.5 0.7 9.6 0.4 13.7 2.1 9.9 60.2 0.8 1.0 0.7 61.3 7.0 0.6 53.4 2.8 4.6 7.8 20.4 1.8 3.1 1.4 0.6 8.7 8.5 278.3 7.6 0.7 8.9 3.0 4.4 63.4 0.2 1.5 1.1 3.8 4.0 2.7 0.9 12.8 3.2 0.2 3.0 14.9 10.7 0.3 0.6 4.8 0.3 1.7 21.5 6.5 0.1 1.0 40.3 0.5 0.2 0.2 1.8 0.0 0.1 0.1 0.3 0.3 0.2 2.5 0.3 0.0 6.9 0.2 3.1 0.2 0.1 5.1 3.6 0.4 0.3 39.6 0.5 0.3 2.1 0.5 2.2 0.6 0.4 0.4 0.0 3.9 0.5 1.0 0.3 61.8 1.2 2.0 13.0 0.1 0.1 29.1 0.0 1.9 0.1 0.0 11.8 40.5 0.9 1.1 30.4 5.2 138.0 0.7 0.0 4.1 2.0 0.4 0.1 6.0 4.4 24.7 6.8 11.9 1.2 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.1 0.1 0.1 0.1 0.0 8.5 9.6 2.1 9.9 7.8 20.4 8.7 8.5 4.4 3.2 10.7 6.5 0.4 0.0 0.5 20.2 0.7 0.8 1.9 0.0 0.6 4.8 24.7 13.7 8.3 5.7 0.6 0.0 2.1 0.2 0.1 0.1 0.0 0.3 0.8 35.7 36.0 1.3 0.0 0.0 15.0 0.2 3.6 16.9 0.0 23.4 3.8 545.2 0.7 8.9 3.2 3.3 46.9 0.0 0.0 0.0 1.2 2.5 20.2 1.4 5.4 1.0 0.0 0.2 0.0 11.6 20.9 0.4 0.0 55.3 5.0 14.3 0.0 2.5 2.9 0.5 0.0 7.2 14.8 1.1 2.9 0.3 0.3 0.3 1.1 33.1 0.0 2.5 GRPEL2 "DKFZp451C205, FLJ23713, Mt-GrpE#2" ENSG00000164284 "GrpE like 2, mitochondrial" Q8TAA5 5 149345430-149354583 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 44.9" "Cell type enhanced" "Detected in many" "Endothelial cells: 36.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018173, HPA023211" Approved Enhanced Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Mitochondria "HPA018173: AB_1850358, HPA023211: AB_1850360" "unprognostic (3.13e-2)" "unprognostic (1.69e-1)" "prognostic favorable (3.87e-5)" "prognostic unfavorable (2.21e-4)" "unprognostic (3.22e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (6.16e-8)" "unprognostic (1.34e-1)" "unprognostic (8.16e-2)" "unprognostic (3.43e-2)" "unprognostic (2.21e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (4.20e-4)" "unprognostic (3.40e-1)" "unprognostic (1.79e-1)" "unprognostic (2.20e-1)" "unprognostic (2.26e-1)" 6.8 4.2 4.6 5.9 5.0 5.0 5.1 8.8 6.2 13.4 2.8 4.1 4.8 4.3 4.1 44.9 3.8 3.5 8.2 4.8 6.1 6.2 4.7 9.3 7.2 6.3 5.5 5.4 3.7 6.5 3.0 7.5 6.6 3.9 3.9 5.6 7.2 4.0 8.8 4.5 5.0 3.6 5.3 4.8 5.5 4.6 6.0 5.3 6.5 5.1 11.0 4.9 11.0 5.9 16.3 9.5 12.5 44.2 7.9 8.1 25.2 14.8 11.9 13.5 19.1 22.7 10.6 17.5 15.0 7.6 18.0 12.4 20.3 20.8 18.8 9.0 18.0 21.1 16.0 11.9 22.1 21.2 11.1 12.4 24.5 16.3 26.8 5.9 9.7 22.1 18.5 39.4 9.9 11.2 13.4 17.1 16.0 9.9 34.5 17.3 17.0 22.0 8.8 15.7 25.3 20.7 14.7 25.9 44.5 9.3 23.0 24.5 11.2 14.6 16.3 10.4 21.3 14.7 21.6 16.6 14.3 28.9 14.5 9.9 2.5 3.6 5.1 2.4 6.1 3.9 7.6 5.6 3.9 1.8 9.9 7.5 2.0 3.8 2.8 1.1 15.1 4.8 4.6 5.0 8.8 6.2 4.8 6.1 6.3 5.5 6.6 5.3 6.0 5.9 20.9 9.6 6.4 2.3 3.3 17.8 5.3 9.9 9.6 6.1 7.0 6.0 8.8 4.3 9.3 9.2 8.4 9.2 3.5 5.1 1.9 5.3 11.6 2.3 4.9 36.0 6.0 11.4 4.3 6.0 18.2 6.0 3.6 5.6 2.5 6.6 20.3 7.1 6.0 3.3 5.1 4.5 10.2 9.7 7.4 5.4 4.1 2.7 7.2 5.6 4.5 5.4 2.1 3.0 4.9 7.5 3.1 5.3 4.4 7.1 6.5 6.2 5.0 6.7 0.0 6.1 6.0 22.6 12.0 10.0 19.6 5.6 9.2 5.2 7.2 8.2 GSAP "LOC54103, PION" ENSG00000186088 "Gamma-secretase activating protein" A4D1B5 7 77310751-77416349 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;NK-cells: 110.2;Oligodendrocyte precursor cells: 72.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 12.5;U-937: 17.0" "Region enhanced" "Detected in all" "cerebellum: 15.5" "Low region specificity" "Detected in all" HPA023994 Approved Vesicles NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 64: Macrophages - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA023994: AB_1855386" "prognostic favorable (3.36e-4)" "unprognostic (3.70e-1)" "unprognostic (8.55e-3)" "unprognostic (4.53e-3)" "unprognostic (6.80e-3)" "unprognostic (3.52e-3)" "unprognostic (4.36e-2)" "unprognostic (7.18e-3)" "unprognostic (1.09e-1)" "unprognostic (9.98e-3)" "unprognostic (2.07e-3)" "unprognostic (2.41e-1)" "prognostic unfavorable (3.51e-4)" "unprognostic (3.61e-1)" "unprognostic (1.82e-2)" "unprognostic (9.49e-2)" "prognostic favorable (4.15e-5)" 5.3 5.3 2.5 10.9 2.2 9.4 5.9 1.8 3.4 3.7 3.2 5.0 2.6 4.0 3.8 3.1 6.4 7.9 4.9 2.4 4.1 6.3 16.4 18.4 13.1 3.6 2.9 3.6 5.4 11.8 7.4 3.8 3.0 5.4 4.7 10.9 4.7 5.1 2.0 4.4 7.5 3.8 2.8 18.7 7.8 1.9 4.2 6.1 8.3 3.9 13.0 5.9 2.3 4.1 3.8 2.0 0.0 0.0 0.5 2.4 0.4 2.3 7.7 1.2 3.2 0.6 5.4 0.8 0.2 0.1 4.3 1.8 0.1 1.9 3.4 2.5 1.6 4.1 0.2 10.7 3.3 0.3 0.0 0.9 7.0 6.2 12.5 9.2 0.5 0.0 0.1 0.3 10.5 2.1 0.0 8.2 0.6 6.0 2.7 0.0 0.2 0.2 6.9 3.2 0.2 5.7 2.5 1.2 6.3 0.5 2.3 3.4 0.0 2.0 1.4 0.2 7.1 1.5 0.1 1.4 8.8 17.0 1.6 0.0 13.3 1.4 8.5 12.7 5.2 18.6 2.8 6.0 16.3 16.4 3.6 6.1 1.7 16.7 9.4 0.4 0.1 8.2 2.5 2.2 1.8 3.4 2.4 4.1 3.6 2.9 3.0 2.8 4.2 4.1 15.2 76.9 60.8 29.0 53.3 5.2 11.6 19.3 13.6 17.0 12.5 9.8 8.5 11.5 22.8 3.7 16.7 3.2 60.5 0.7 25.4 8.5 0.1 10.2 1.6 9.2 5.4 4.4 28.2 6.2 0.7 4.9 9.7 15.8 13.3 9.8 3.3 17.2 9.7 20.2 51.9 6.1 10.2 38.2 23.3 0.2 5.3 46.5 8.8 42.2 30.8 41.6 110.2 72.4 12.7 6.8 4.6 3.8 15.4 20.0 1.4 12.0 9.8 20.9 6.6 9.8 3.2 2.5 1.5 8.6 4.5 1.6 22.8 2.0 4.6 17.2 GSTA4 ENSG00000170899 "Glutathione S-transferase alpha 4" O15217 6 52977948-52995304 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 295.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 280.0;Granulosa cells: 335.6;Syncytiotrophoblasts: 450.3;Theca cells: 415.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "non-classical monocyte: 20.0" "Lineage enriched" "Detected in many" 6 "monocytes: 20.0" "Cell line enhanced" "Detected in many" "AF22: 95.4;ASC TERT1: 93.1" "Low region specificity" "Detected in all" HPA048934 Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "HPA048934: AB_2680563" "unprognostic (5.13e-3)" "unprognostic (2.75e-1)" "unprognostic (5.04e-2)" "unprognostic (1.38e-1)" "unprognostic (5.24e-2)" "unprognostic (3.63e-3)" "unprognostic (1.81e-1)" "unprognostic (1.63e-2)" "unprognostic (5.05e-3)" "unprognostic (9.26e-2)" "unprognostic (3.31e-3)" "unprognostic (2.29e-2)" "unprognostic (1.34e-2)" "unprognostic (2.21e-1)" "unprognostic (4.07e-3)" "unprognostic (1.53e-1)" "unprognostic (1.13e-1)" 19.2 295.7 51.2 6.9 52.6 1.7 36.0 55.6 61.0 37.0 37.7 19.2 20.4 27.5 61.2 53.4 24.7 22.9 20.4 53.8 55.5 32.1 34.8 38.7 7.3 44.1 43.5 51.9 31.3 74.4 43.1 48.0 45.2 40.7 24.5 31.2 32.8 28.5 35.9 136.0 19.0 26.2 43.0 13.6 37.2 37.3 48.7 9.9 25.0 36.7 21.4 15.6 40.3 53.8 1.3 10.3 95.4 80.3 56.1 93.1 8.9 13.6 33.7 9.4 16.0 15.6 0.3 1.0 9.1 25.8 10.1 3.9 69.7 13.5 11.8 2.3 29.2 3.3 8.2 54.4 39.8 0.0 2.3 80.1 20.6 12.0 10.1 28.5 59.1 14.1 12.9 15.0 31.9 0.0 1.2 0.3 36.4 58.5 17.3 2.4 41.2 18.6 34.3 1.7 42.2 62.1 0.4 9.9 24.9 48.9 2.5 2.8 28.5 10.0 22.6 9.3 11.6 18.4 2.5 0.5 15.2 1.5 11.0 0.0 0.0 0.0 2.6 0.9 2.0 0.8 0.7 1.2 0.9 2.9 0.5 0.7 0.0 3.2 20.0 1.7 0.8 0.9 51.2 52.6 55.6 61.0 53.8 55.5 44.1 43.5 45.2 43.0 48.7 53.8 15.4 51.3 84.3 22.9 2.2 44.9 22.0 79.0 35.3 39.7 26.1 31.2 10.0 15.7 44.4 27.6 0.0 280.0 3.6 5.6 54.8 14.0 1.4 3.5 24.1 20.0 23.9 9.5 63.4 9.0 108.8 40.5 23.0 4.1 5.7 335.6 31.4 21.1 69.8 37.0 88.2 41.8 57.0 2.5 14.6 9.6 41.7 3.5 96.0 13.1 2.8 70.1 4.1 75.9 62.7 10.8 9.6 39.1 0.8 25.8 12.7 47.7 15.6 11.3 19.7 28.5 36.3 4.7 10.5 96.3 135.5 450.3 3.9 415.9 18.0 21.1 GUCY1A1 "GC-SA3, GUC1A3, GUCY1A3" ENSG00000164116 "Guanylate cyclase 1 soluble subunit alpha 1" Q02108 4 155666726-155737059 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 38.4;Alveolar cells type 2: 56.1;Breast glandular cells: 37.4;Breast myoepithelial cells: 24.9;Distal tubular cells: 19.6;Ductal cells: 21.8;Smooth muscle cells: 49.4" "Cancer enhanced" "Detected in all" "prostate cancer: 24.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 8.2;non-classical monocyte: 10.1;plasmacytoid DC: 11.5" "Group enriched" "Detected in many" 35 "dendritic cells: 11.5;monocytes: 10.1;NK-cells: 8.2" "Cell line enhanced" "Detected in some" "HAP1: 6.8;HEK 293: 5.5;Karpas-707: 9.7;MOLT-4: 18.5;RPTEC TERT1: 12.1;RT4: 14.2;SH-SY5Y: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010887, HPA056004, HPA058617" Uncertain Supported Nucleoplasm NA NA 7100 "Cluster 40: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "CAB010887: AB_259901, HPA056004: AB_2683007, HPA058617: AB_2732624" "unprognostic (4.81e-3)" "unprognostic (2.60e-1)" "unprognostic (3.03e-1)" "unprognostic (2.15e-1)" "unprognostic (1.99e-2)" "unprognostic (7.77e-3)" "unprognostic (1.07e-1)" "prognostic favorable (2.38e-4)" "unprognostic (1.85e-3)" "unprognostic (6.46e-2)" "unprognostic (3.42e-2)" "unprognostic (7.16e-2)" "prognostic unfavorable (7.59e-4)" "unprognostic (1.60e-2)" "prognostic unfavorable (3.59e-4)" "unprognostic (2.27e-1)" "unprognostic (6.55e-3)" 14.4 7.8 10.1 17.0 24.1 1.2 15.4 2.8 14.0 14.5 0.1 27.1 8.7 16.1 6.2 7.5 9.5 12.6 33.7 12.7 8.0 15.6 8.0 21.0 8.5 5.3 10.0 5.6 13.1 31.4 3.9 25.9 4.5 25.8 10.3 17.0 5.3 13.9 5.1 2.5 9.2 28.9 8.7 14.1 8.6 1.2 10.2 7.5 7.2 18.7 9.2 7.3 6.6 8.5 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 6.8 0.0 0.0 0.0 5.5 1.3 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 3.6 0.0 9.7 0.0 0.0 18.5 0.0 0.0 0.0 0.2 4.1 0.0 3.0 12.1 14.2 2.5 8.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.2 0.0 2.3 0.1 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.1 8.2 10.1 11.5 0.0 1.0 10.1 24.1 2.8 14.0 12.7 8.0 5.3 10.0 4.5 8.7 10.2 8.5 38.4 9.6 56.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 37.4 24.9 0.0 0.0 6.8 11.0 0.0 0.4 1.7 0.0 19.6 21.8 0.0 5.5 9.7 10.9 0.0 0.0 0.0 2.0 0.3 8.3 0.0 15.2 3.8 3.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 12.9 2.2 0.0 0.0 0.0 49.4 0.0 0.0 0.0 0.0 0.3 0.6 0.1 0.0 0.0 GUCY1B1 "GC-S-beta-1, GC-SB3, GUC1B3, GUCY1B3" ENSG00000061918 "Guanylate cyclase 1 soluble subunit beta 1" Q02153 4 155758992-155807811 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 20.2;Ductal cells: 22.9;Glandular and luminal cells: 15.5;Proximal tubular cells: 22.2;Smooth muscle cells: 36.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "intermediate monocyte: 7.2;non-classical monocyte: 23.9" "Lineage enriched" "Detected in many" 13 "monocytes: 23.9" "Cell line enhanced" "Detected in many" "HEL: 46.0;Karpas-707: 23.7;MOLT-4: 29.9;RPTEC TERT1: 42.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010890, HPA020870" Approved Approved Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "CAB010890: AB_259911, HPA020870: AB_1850444" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (3.55e-2)" "unprognostic (9.10e-3)" "unprognostic (4.69e-2)" "unprognostic (1.41e-2)" "unprognostic (6.88e-2)" "unprognostic (6.69e-3)" "unprognostic (3.03e-3)" "unprognostic (1.47e-1)" "unprognostic (8.37e-2)" "unprognostic (2.84e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (7.35e-3)" "prognostic unfavorable (3.23e-4)" "unprognostic (2.14e-1)" "unprognostic (6.36e-3)" 13.8 7.1 23.6 15.6 30.0 2.2 10.0 5.3 36.6 12.6 0.0 28.9 5.8 16.4 6.0 8.1 13.7 13.3 18.7 30.1 28.2 13.2 7.7 16.5 10.4 9.8 13.9 5.8 10.9 50.3 6.0 43.6 22.8 13.6 8.7 34.7 5.5 12.2 5.9 3.5 11.1 25.0 6.4 11.0 13.8 2.4 14.8 7.2 7.3 14.9 7.3 10.0 11.1 17.0 0.0 0.5 6.5 0.0 2.2 11.4 0.0 2.0 3.6 0.2 0.1 0.0 0.0 0.0 3.0 1.1 5.0 0.1 13.6 0.3 0.8 0.0 4.6 46.0 0.0 0.0 1.2 0.0 0.0 5.1 0.4 0.0 0.2 4.2 0.1 10.2 0.0 23.7 3.0 2.1 29.9 0.1 0.4 0.0 3.2 3.5 0.9 0.7 42.9 4.4 0.7 7.8 0.0 0.2 0.0 6.4 0.0 0.0 0.0 7.3 1.6 12.4 9.5 0.3 0.0 0.0 15.6 0.0 0.0 1.4 0.5 0.5 0.0 7.2 0.0 0.1 0.0 0.0 1.8 0.2 0.0 0.0 0.5 1.3 23.9 1.6 0.0 5.8 23.6 30.0 5.3 36.6 30.1 28.2 9.8 13.9 22.8 6.4 14.8 17.0 20.2 6.4 7.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 2.2 0.0 0.0 0.0 9.2 0.0 1.1 1.1 0.0 5.9 22.9 0.0 3.7 4.3 3.4 0.0 0.0 0.0 4.2 0.2 5.4 0.0 15.5 1.3 4.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.0 22.2 0.0 0.0 0.0 0.0 36.1 0.0 0.0 0.0 0.0 0.7 0.4 0.7 0.0 0.0 GVQW3 ENSG00000179240 "GVQW motif containing 3" Q3ZCU0 11 76381303-76414619 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 14.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 3.9;Distal tubular cells: 9.8;granulocytes: 3.8;Granulosa cells: 7.0;Proximal tubular cells: 6.7;Theca cells: 5.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA057405 Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Centrosome" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Centrosome" "Endoplasmic reticulum" "HPA057405: AB_2683429" "unprognostic (8.90e-2)" "unprognostic (1.16e-1)" "unprognostic (8.27e-2)" "unprognostic (1.92e-1)" "unprognostic (9.04e-3)" "unprognostic (8.56e-2)" "unprognostic (8.87e-2)" "unprognostic (2.91e-2)" "unprognostic (7.28e-3)" "unprognostic (2.21e-1)" "unprognostic (1.04e-2)" "unprognostic (1.49e-1)" "unprognostic (4.05e-4)" "unprognostic (7.45e-2)" "unprognostic (1.09e-1)" "unprognostic (9.28e-2)" "unprognostic (2.13e-1)" 1.1 1.5 1.5 1.4 1.6 1.1 1.9 3.2 2.1 1.7 4.4 1.3 1.4 1.8 1.9 0.4 2.0 0.7 1.0 1.4 0.8 1.4 0.7 0.9 1.9 0.5 0.1 2.2 6.5 1.0 2.4 0.8 0.6 1.2 1.5 14.2 1.9 0.8 1.1 1.4 1.3 0.9 0.0 1.7 1.4 3.4 1.2 2.4 1.9 0.6 1.6 0.9 1.3 1.5 1.1 1.2 4.4 3.2 1.2 1.6 1.5 0.6 0.5 1.1 1.1 3.0 2.0 3.6 1.2 0.5 1.3 2.6 1.9 0.8 1.9 2.0 1.2 1.9 5.0 1.3 0.7 2.5 1.2 0.7 1.2 1.4 0.8 1.0 0.9 4.9 1.2 2.3 0.4 1.3 2.4 3.8 0.9 0.9 1.4 3.7 2.9 1.9 0.7 0.8 6.5 2.9 1.2 0.7 0.7 1.7 2.1 0.8 0.6 2.1 2.2 3.2 0.7 2.1 1.6 4.6 0.8 1.7 1.1 1.5 0.3 0.4 0.4 0.2 0.3 0.5 0.6 0.5 0.2 0.6 0.6 0.6 1.0 0.8 0.2 0.3 0.8 0.2 1.5 1.6 3.2 2.1 1.4 0.8 0.5 0.1 0.6 0.0 1.2 1.5 2.1 0.0 3.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.8 2.3 0.0 0.0 2.5 1.8 0.0 1.1 1.7 0.0 9.8 1.2 0.0 2.4 2.5 0.8 0.0 0.0 0.0 0.6 0.6 1.4 0.0 0.6 3.8 7.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 6.7 2.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.7 0.9 5.5 0.0 0.0 GYPC "CD236, CD236R, Ge, GPC, GYPD" ENSG00000136732 "Glycophorin C (Gerbich blood group)" P04921 2 126656133-126696667 "Blood group antigen proteins, CD markers, Predicted membrane proteins" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 441.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 1728.6;Hofbauer cells: 488.7" "Cancer enhanced" "Detected in all" "melanoma: 66.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 433.1;K-562: 362.1;SK-MEL-30: 668.4;U-266/70: 363.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008965, CAB009445" Enhanced Supported "Plasma membrane" NA NA 970000 "Cluster 20: T-cells - T-cell receptor" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane" "CAB009445: AB_2116251, HPA008965: AB_1078455" "unprognostic (1.63e-2)" "unprognostic (7.14e-3)" "unprognostic (8.39e-2)" "unprognostic (3.31e-3)" "unprognostic (4.19e-2)" "unprognostic (1.69e-2)" "unprognostic (8.82e-2)" "unprognostic (3.52e-1)" "unprognostic (1.19e-1)" "unprognostic (2.21e-1)" "unprognostic (1.25e-1)" "unprognostic (1.11e-1)" "unprognostic (2.05e-2)" "unprognostic (2.73e-2)" "unprognostic (1.51e-1)" "unprognostic (2.29e-1)" "unprognostic (8.00e-3)" 172.3 73.0 17.3 51.5 17.6 441.0 109.2 17.5 30.8 75.7 20.2 89.1 18.2 62.3 20.2 42.3 68.4 56.3 161.9 16.5 20.2 58.4 18.5 101.4 110.5 22.2 18.4 91.5 34.8 9.6 16.9 50.3 22.0 46.5 19.3 10.3 26.4 56.1 212.7 37.0 52.9 55.9 20.6 98.5 41.0 7.3 23.6 59.6 33.3 204.1 75.9 73.0 54.4 24.9 1.3 0.0 152.0 0.2 116.1 100.5 0.2 24.0 186.4 28.9 84.9 0.0 0.2 0.6 0.4 69.6 107.6 0.3 85.7 0.1 9.5 79.7 0.0 279.0 0.0 0.0 433.1 99.0 0.7 237.4 0.0 23.1 0.1 2.3 1.0 190.4 362.1 214.6 70.5 0.0 0.1 148.9 46.7 0.0 0.4 18.1 12.1 0.4 11.8 0.0 0.2 0.0 0.3 0.0 668.4 20.7 0.0 258.5 65.7 107.3 1.0 7.3 1.2 363.9 257.4 0.5 51.4 135.8 99.3 0.8 28.6 2.2 153.1 40.3 172.2 95.8 136.7 186.5 50.0 102.6 190.5 188.3 21.9 81.1 24.7 27.1 179.4 119.0 17.3 17.6 17.5 30.8 16.5 20.2 22.2 18.4 22.0 20.6 23.6 24.9 260.7 6.4 7.7 0.7 152.7 38.0 3.4 17.0 43.3 0.6 14.6 110.5 34.9 84.4 6.0 14.7 2.1 4.9 194.0 0.0 135.0 202.9 1.6 3.6 99.8 157.2 0.0 1728.6 0.4 4.9 6.9 170.5 10.2 2.5 22.9 23.3 229.2 6.2 488.7 0.0 0.5 1.1 0.0 118.0 108.5 4.9 87.3 134.9 305.9 15.0 98.0 5.1 204.9 6.0 0.1 6.0 0.4 69.2 250.9 9.4 0.0 8.1 1.7 2.6 59.2 65.8 88.6 0.2 0.7 41.9 26.6 9.0 228.0 31.8 1.6 2.9 GZMB "CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT" ENSG00000100453 "Granzyme B" P10144 14 24630954-24634267 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 68.2;lymphoid tissue: 37.1" "Group enriched" "Detected in many" 5 "dendritic cells: 2050.2;NK-cells: 1704.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "plasmacytoid DC: 6765.2" "Lineage enriched" "Detected in all" 5 "dendritic cells: 6765.2" "Cell line enriched" "Detected in some" 6 "HMC-1: 22.0" "CAB000376, HPA003418" Enhanced "Secreted to blood" NA NA 2170 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB000376: AB_323716, HPA003418: AB_1079020" "prognostic favorable (7.27e-4)" "unprognostic (2.82e-3)" "unprognostic (8.54e-2)" "prognostic favorable (1.58e-5)" "unprognostic (2.07e-3)" "unprognostic (1.48e-3)" "unprognostic (4.43e-2)" "unprognostic (8.25e-2)" "unprognostic (3.70e-2)" "unprognostic (3.05e-3)" "unprognostic (4.26e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (1.10e-7)" "unprognostic (1.24e-1)" "unprognostic (1.48e-1)" "unprognostic (1.29e-1)" "unprognostic (2.71e-3)" 8.2 1.7 1.2 17.8 1.3 68.2 2.1 1.2 3.9 1.2 1.4 2.5 2.3 7.1 1.6 3.8 1.5 6.5 1.8 1.2 7.9 1.5 4.1 15.3 37.1 1.5 1.5 0.3 1.0 0.7 0.7 3.3 1.6 1.4 2.2 0.0 2.3 1.4 2.0 0.4 4.4 4.3 1.4 28.9 3.5 0.5 1.8 9.7 1.9 1.5 34.6 18.5 1.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.0 0.7 2.8 9.9 3.0 5.3 1338.5 4.0 16.0 7.0 95.2 641.6 6.3 3.1 29.1 607.5 43.1 507.8 6.0 6765.2 2.7 1607.1 1.2 1.3 1.2 3.9 1.2 7.9 1.5 1.5 1.6 1.4 1.8 1.3 4.3 6.4 36.0 0.0 15.9 2.8 0.3 0.0 0.0 0.0 0.9 0.8 1.1 4.3 7.4 0.0 0.0 0.4 2050.2 0.6 0.0 1.6 0.0 0.4 0.5 2.7 0.0 11.8 0.0 0.0 0.1 5.1 9.2 0.5 17.7 0.0 4.2 1.2 0.2 0.0 0.0 0.6 0.0 4.8 9.0 0.2 0.0 27.1 42.7 1.0 11.6 0.0 1704.4 0.0 0.1 0.1 2.3 0.0 86.8 0.2 0.6 3.1 4.4 0.0 0.0 1.3 1.3 0.0 0.1 0.4 4.1 0.3 373.8 0.0 0.6 0.1 GZMK "PRSS, TRYP2" ENSG00000113088 "Granzyme K" P49863 5 55024256-55034570 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 99.6" "Group enriched" "Detected in many" 4 "dendritic cells: 136.3;T-cells: 301.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 741.6;NK-cell: 505.5" "Group enriched" "Detected in many" 199 "NK-cells: 505.5;T-cells: 741.6" "Cell line enriched" "Detected in single" 10 "JURKAT: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA063181, HPA065895" Enhanced "Secreted to blood" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA063181: AB_2684955, HPA065895: " "prognostic favorable (8.68e-4)" "unprognostic (3.26e-3)" "unprognostic (2.23e-2)" "unprognostic (1.83e-3)" "unprognostic (2.61e-2)" "unprognostic (1.12e-3)" "unprognostic (1.03e-3)" "unprognostic (8.13e-3)" "unprognostic (3.50e-2)" "unprognostic (4.53e-2)" "unprognostic (9.74e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.06e-4)" "unprognostic (2.04e-1)" "unprognostic (2.42e-1)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" 3.0 3.9 0.1 19.4 0.1 10.5 4.9 0.1 0.4 4.3 0.3 3.4 1.6 4.0 4.5 3.0 2.0 11.6 2.0 0.1 0.2 1.7 10.7 5.9 99.6 0.5 0.2 2.7 1.0 0.8 0.5 0.5 0.3 3.2 4.6 0.0 4.6 1.0 0.2 0.6 7.3 2.2 0.2 30.4 6.5 1.2 0.3 11.9 2.3 0.3 27.8 8.0 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.9 1.1 164.3 1.0 741.6 0.5 100.2 457.3 0.5 0.5 4.9 77.4 3.1 505.5 0.9 0.9 7.0 95.5 0.1 0.1 0.1 0.4 0.1 0.2 0.5 0.2 0.3 0.2 0.3 0.3 3.8 3.2 7.0 0.0 10.7 1.5 0.1 0.0 1.8 0.0 1.5 1.7 0.1 2.8 0.6 0.0 0.0 0.0 136.3 0.1 0.0 0.0 1.3 0.8 0.4 0.8 0.0 4.4 0.0 0.0 0.0 1.2 4.1 0.8 2.5 0.0 8.6 1.5 0.2 0.0 0.0 0.0 0.0 10.3 2.5 1.2 0.0 6.4 1.8 0.0 5.1 0.0 29.9 0.0 0.1 0.0 0.0 0.0 45.1 0.1 0.2 0.8 0.0 0.0 0.0 1.8 1.7 0.0 0.3 0.2 0.6 0.3 301.9 0.0 0.0 0.1 HABP2 "FSAP, HABP, HGFAL, PHBP" ENSG00000148702 "Hyaluronan binding protein 2" Q14520 10 113550837-113589602 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "liver: 437.3" "Group enriched" "Detected in some" 5 "Cholangiocytes: 124.4;Hepatocytes: 221.4" "Cancer enriched" "Detected in many" 5 "liver cancer: 92.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "OE19: 64.7;RPTEC TERT1: 50.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA019518 Uncertain "Secreted to blood" NA NA 20200000000 4400000000 "Cluster 62: Liver - Hemostasis" "Cluster 21: OE19 - Mitochondria" "Cluster 15: Hepatocytes - Hemostasis" "HPA019518: AB_1850467" "unprognostic (3.89e-2)" "unprognostic (6.15e-2)" "unprognostic (1.33e-1)" "unprognostic (1.24e-1)" "unprognostic (1.45e-1)" "unprognostic (6.92e-2)" "unprognostic (1.01e-1)" "unprognostic (5.86e-3)" "unprognostic (1.67e-1)" "unprognostic (9.78e-2)" "unprognostic (5.10e-2)" "unprognostic (4.77e-2)" "unprognostic (9.18e-3)" "unprognostic (2.62e-3)" "unprognostic (2.11e-1)" "unprognostic (3.22e-1)" "unprognostic (9.05e-3)" 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.9 0.9 0.0 0.0 3.1 2.9 1.7 0.0 2.2 36.0 3.8 0.1 0.0 14.2 437.3 0.8 0.0 0.0 0.0 0.0 17.3 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.0 0.5 0.0 0.0 0.1 12.1 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 64.7 0.0 0.0 0.1 0.0 50.9 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 2.3 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 124.4 0.0 1.8 0.0 0.0 0.0 0.0 3.9 31.4 0.5 10.8 0.8 0.4 0.0 5.3 1.0 3.9 0.0 0.0 17.9 6.5 0.0 0.0 5.3 221.4 1.0 0.0 0.0 0.2 0.0 5.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 12.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.1 HACD3 "B-ind1, HSPC121, PTPLAD1" ENSG00000074696 "3-hydroxyacyl-CoA dehydratase 3" Q9P035 15 65530418-65578349 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014837, HPA060347" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum" "HPA014837: AB_1855914, HPA060347: AB_2684260" "unprognostic (1.51e-2)" "unprognostic (2.89e-1)" "unprognostic (2.29e-1)" "unprognostic (2.18e-1)" "unprognostic (3.52e-1)" "unprognostic (1.92e-2)" "unprognostic (1.67e-1)" "unprognostic (2.28e-1)" "unprognostic (3.36e-2)" "unprognostic (1.09e-1)" "unprognostic (1.73e-1)" "unprognostic (2.57e-1)" "prognostic favorable (3.09e-5)" "unprognostic (3.44e-2)" "unprognostic (5.33e-2)" "unprognostic (1.10e-2)" "unprognostic (2.04e-2)" 23.1 84.1 56.1 18.5 57.1 17.3 74.4 64.6 67.5 40.2 73.2 30.0 28.9 29.9 43.0 19.2 32.4 34.1 11.8 54.3 87.8 79.6 119.1 30.3 18.8 68.3 79.6 47.8 29.8 61.5 44.2 37.2 87.2 41.6 34.3 54.0 28.6 34.3 6.9 27.7 29.2 28.1 70.0 21.2 68.7 34.6 88.3 29.0 70.8 7.8 20.3 43.0 17.8 75.8 88.9 194.4 211.3 106.2 130.3 78.0 99.8 95.9 82.4 106.6 119.6 149.9 129.1 110.8 81.8 104.7 132.6 237.9 344.4 80.1 94.8 61.9 191.8 88.1 88.7 165.3 65.9 110.6 64.9 80.3 58.7 73.3 52.5 102.7 105.5 65.1 117.5 40.8 174.3 105.6 82.5 86.0 180.6 235.3 65.4 91.8 178.9 125.0 152.1 151.2 126.8 111.9 103.6 114.9 110.5 197.5 117.1 57.9 84.2 134.4 117.6 66.9 134.9 79.1 251.2 154.5 89.7 105.8 82.6 8.5 7.5 2.5 31.7 11.2 36.1 23.7 28.6 30.2 13.2 22.2 33.0 32.9 1.0 23.2 12.7 17.4 24.6 22.7 56.1 57.1 64.6 67.5 54.3 87.8 68.3 79.6 87.2 70.0 88.3 75.8 63.6 64.1 64.8 84.5 18.7 0.0 60.5 0.0 76.2 121.3 94.8 64.5 9.9 62.9 27.9 176.6 100.1 189.1 23.8 6.1 25.4 71.3 107.2 62.8 76.2 51.8 43.7 67.3 57.5 46.3 124.4 62.7 73.4 39.8 16.4 127.0 42.1 165.2 51.2 139.7 97.1 26.3 0.0 23.1 0.0 32.5 87.3 22.2 0.0 29.0 5.2 89.8 16.5 57.8 66.7 32.1 18.2 88.4 28.9 71.5 28.3 56.2 36.5 83.7 78.9 40.9 41.9 156.9 110.3 54.3 0.0 113.1 22.3 136.2 45.1 78.7 HACL1 "2-HPCL, HPCL, PHYH2" ENSG00000131373 "2-hydroxyacyl-CoA lyase 1" Q9UJ83 3 15560699-15601852 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 117.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 117.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035496, HPA035497, HPA073760" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles Nucleoplasm "HPA035496: AB_10601328, HPA035497: AB_2674653, HPA073760: AB_2686633" "unprognostic (6.64e-3)" "unprognostic (2.82e-2)" "unprognostic (2.24e-3)" "unprognostic (3.82e-1)" "unprognostic (4.08e-2)" "unprognostic (1.77e-1)" "unprognostic (2.96e-2)" "unprognostic (6.31e-2)" "unprognostic (8.27e-3)" "unprognostic (5.23e-2)" "unprognostic (3.30e-2)" "unprognostic (1.44e-1)" "prognostic favorable (2.63e-5)" "unprognostic (6.62e-2)" "unprognostic (2.66e-1)" "unprognostic (3.23e-2)" "unprognostic (9.07e-2)" 14.4 12.0 7.5 8.2 7.8 11.6 14.6 10.4 10.5 9.1 7.9 10.0 56.6 8.3 16.6 7.5 10.8 8.8 11.0 7.6 7.0 26.0 51.8 9.7 14.1 7.4 7.2 7.5 15.2 20.0 7.8 7.8 7.0 10.8 12.0 12.2 9.1 9.1 17.6 10.6 27.7 9.5 7.4 11.4 13.2 26.7 6.8 13.9 20.4 10.6 14.5 10.3 6.4 10.0 15.1 28.6 8.2 30.7 13.4 12.4 82.3 14.2 22.0 26.6 26.3 27.3 14.3 14.6 9.7 18.7 10.5 10.4 18.7 25.3 23.8 13.6 36.4 25.4 17.7 24.7 20.3 30.5 23.1 13.7 16.2 37.9 16.6 8.3 31.4 18.3 24.0 21.2 22.9 28.7 14.0 12.6 19.7 19.7 29.7 14.4 21.5 19.6 26.4 20.2 9.6 12.3 22.4 19.0 25.2 12.8 8.5 25.4 22.5 14.1 14.6 17.4 24.7 27.2 50.9 28.5 27.1 26.4 17.2 117.3 16.0 18.3 14.4 20.1 21.2 15.4 15.5 18.0 16.0 21.2 14.8 16.1 3.4 24.1 24.2 10.2 19.8 13.0 7.5 7.8 10.4 10.5 7.6 7.0 7.4 7.2 7.0 7.4 6.8 10.0 12.4 9.6 17.3 34.9 22.1 10.3 12.0 13.5 20.5 19.3 9.1 10.2 6.4 14.3 15.6 11.0 29.2 27.2 15.7 6.1 13.7 16.0 66.6 12.6 6.0 12.3 9.1 8.2 67.4 25.2 18.0 12.0 11.2 5.4 13.3 12.7 8.9 24.3 13.2 13.5 55.8 7.5 10.2 9.3 8.1 56.8 23.3 8.8 12.4 25.3 19.3 24.8 8.2 40.7 38.8 14.5 11.2 15.4 21.4 9.0 41.9 39.7 29.8 38.3 6.6 9.0 11.2 51.1 24.4 8.6 7.1 18.9 19.4 15.1 10.6 7.9 HADHA "GBP, LCEH, LCHAD, MTPA" ENSG00000084754 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha" P40939 2 26190635-26244672 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 502.5" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 527.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015536, HPA056070" Approved Enhanced Mitochondria NA NA 470000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA015536: AB_1850473, HPA056070: AB_2683026" "unprognostic (2.02e-1)" "unprognostic (1.38e-2)" "unprognostic (2.55e-1)" "unprognostic (3.43e-1)" "unprognostic (2.67e-2)" "unprognostic (3.23e-2)" "unprognostic (1.25e-2)" "unprognostic (2.02e-1)" "unprognostic (5.16e-2)" "unprognostic (3.45e-1)" "unprognostic (3.81e-1)" "unprognostic (1.16e-1)" "prognostic favorable (3.68e-5)" "unprognostic (7.97e-2)" "unprognostic (1.71e-1)" "unprognostic (2.87e-3)" "unprognostic (2.64e-2)" 105.0 125.3 57.7 31.1 60.7 46.3 94.9 65.0 69.6 72.6 59.1 108.4 115.0 61.8 30.7 90.1 60.1 32.4 330.2 52.8 61.9 99.0 156.7 66.9 35.3 64.4 62.2 77.8 101.4 95.0 57.4 39.2 64.2 60.2 76.1 14.9 77.9 33.4 502.5 95.7 106.2 57.4 61.8 68.4 93.8 49.0 62.4 46.7 59.5 300.7 58.5 79.1 73.6 67.2 105.7 88.1 58.4 90.8 221.1 139.9 51.5 80.6 84.7 78.5 67.7 114.7 104.1 71.7 50.2 138.4 78.6 66.8 103.4 152.6 72.5 139.1 103.6 103.3 86.2 197.9 73.3 132.2 69.2 142.7 101.6 112.4 109.3 82.8 127.7 70.4 140.2 133.2 101.1 128.2 63.4 137.7 50.1 77.5 134.1 52.9 128.5 143.7 90.3 125.3 41.9 85.1 94.6 104.6 102.4 44.5 52.2 125.8 127.1 48.8 70.7 69.9 58.0 44.8 86.5 113.4 77.6 150.2 56.2 22.5 84.0 33.5 31.8 92.3 39.1 40.5 36.8 38.7 80.8 31.2 42.6 40.1 20.9 38.8 86.1 31.3 50.9 89.9 57.7 60.7 65.0 69.6 52.8 61.9 64.4 62.2 64.2 61.8 62.4 67.2 122.4 89.8 99.0 47.0 101.2 89.0 137.5 139.9 97.3 35.6 89.7 96.4 349.9 82.9 128.0 77.3 52.1 182.0 95.1 242.1 131.0 120.8 39.2 73.3 121.1 99.1 91.4 155.9 22.8 108.5 94.7 96.1 100.4 85.5 139.9 140.3 84.3 185.1 163.0 20.2 28.2 156.5 89.5 136.8 106.0 74.3 92.6 145.0 81.8 12.2 170.7 65.4 93.7 30.7 37.4 90.0 195.6 84.2 90.4 76.2 527.4 182.5 84.8 62.3 52.6 129.9 109.6 147.9 54.9 136.5 103.3 129.2 100.5 154.7 216.7 104.4 HADHB MTPB ENSG00000138029 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta" P55084 2 26243170-26290465 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 793.3;skeletal muscle: 950.6;tongue: 1097.1" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1167.5;Distal tubular cells: 520.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037539, HPA037540, HPA066099" Enhanced Supported Mitochondria No No 61000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA037539: AB_10671374, HPA037540: AB_2675531, HPA066099: AB_2685618" "unprognostic (5.15e-2)" "unprognostic (8.72e-2)" "unprognostic (8.21e-2)" "unprognostic (8.67e-2)" "unprognostic (7.70e-2)" "unprognostic (2.59e-2)" "unprognostic (7.29e-2)" "unprognostic (9.70e-2)" "unprognostic (2.01e-1)" "unprognostic (2.09e-1)" "unprognostic (2.03e-1)" "unprognostic (8.94e-2)" "prognostic favorable (1.37e-9)" "unprognostic (2.47e-1)" "unprognostic (2.50e-1)" "unprognostic (2.88e-1)" "unprognostic (9.68e-2)" 127.0 224.7 120.6 51.1 135.4 58.8 91.3 146.4 138.1 65.2 128.0 110.7 224.2 55.9 73.7 101.3 68.8 64.3 793.3 109.0 138.1 231.4 324.8 64.7 54.9 135.9 141.6 78.4 83.7 209.5 48.1 65.6 139.6 77.1 113.2 63.0 104.8 75.0 950.6 74.4 184.4 79.0 141.4 75.8 109.0 67.1 143.3 53.1 90.8 1097.1 62.5 89.2 64.1 152.8 108.2 83.2 56.6 102.2 342.1 190.1 57.9 89.0 134.6 89.0 86.8 100.5 101.7 53.9 60.8 145.3 100.1 82.8 95.2 124.8 109.2 121.1 83.1 123.6 44.9 194.2 145.9 100.6 90.0 183.7 201.6 92.7 149.0 151.0 168.2 81.0 105.2 83.9 189.5 78.0 57.1 190.7 39.8 160.2 89.0 61.7 188.3 103.2 183.3 148.9 27.2 93.7 151.7 169.8 239.5 68.5 105.4 177.9 118.0 83.5 86.9 79.3 65.1 62.6 101.1 94.7 95.5 158.4 84.4 95.7 168.1 66.4 45.2 150.3 57.6 65.5 61.3 56.6 154.2 49.7 55.8 51.3 72.7 88.2 123.3 51.8 94.7 135.6 120.6 135.4 146.4 138.1 109.0 138.1 135.9 141.6 139.6 141.4 143.3 152.8 106.5 48.1 36.5 63.0 48.3 62.1 136.5 183.3 49.5 29.3 49.5 52.3 1167.5 104.4 107.7 97.5 56.3 227.9 42.4 129.5 520.4 124.0 93.4 59.5 49.0 75.2 74.9 85.2 32.7 57.2 75.2 79.5 53.0 60.2 62.8 94.2 69.9 277.6 139.6 13.5 33.0 93.4 114.0 98.1 67.4 99.7 56.5 78.1 88.9 27.2 110.2 65.0 32.0 35.2 47.5 58.4 134.8 62.8 37.1 60.5 376.0 321.1 73.5 80.0 72.3 72.9 80.7 120.4 49.4 53.8 54.7 186.6 45.2 194.0 113.5 110.3 HAUS4 "C14orf94, FLJ20424" ENSG00000092036 "HAUS augmin like complex subunit 4" Q9H6D7 14 22946228-22957161 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029803 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "HPA029803: AB_10601428" "unprognostic (8.47e-3)" "unprognostic (3.52e-1)" "unprognostic (6.47e-2)" "unprognostic (7.59e-2)" "unprognostic (3.08e-2)" "unprognostic (1.73e-1)" "unprognostic (7.54e-2)" "unprognostic (4.32e-3)" "unprognostic (2.92e-2)" "unprognostic (2.87e-2)" "unprognostic (7.70e-2)" "unprognostic (8.66e-2)" "unprognostic (3.00e-2)" "unprognostic (6.94e-2)" "unprognostic (3.16e-1)" "unprognostic (1.96e-1)" "prognostic unfavorable (2.24e-4)" 29.3 24.8 12.8 29.2 13.8 63.5 39.7 12.9 15.6 33.7 14.4 32.3 28.1 26.2 22.2 30.5 31.0 26.4 26.5 11.8 13.6 26.0 32.2 31.7 40.7 15.2 14.2 52.8 45.2 27.6 14.5 22.4 15.0 26.1 30.2 10.4 33.2 26.4 19.1 39.3 30.6 24.3 13.9 37.7 32.0 12.9 13.8 30.8 27.7 22.9 36.7 29.0 31.7 15.6 77.0 51.2 55.5 56.9 42.0 50.4 86.6 36.5 48.2 39.3 56.1 37.0 88.5 146.2 17.2 22.3 29.2 75.5 31.2 44.9 34.5 39.8 23.0 48.1 35.8 90.2 37.7 63.3 77.8 35.7 84.7 17.5 50.9 48.2 71.1 82.0 35.8 71.2 41.6 58.1 69.8 56.7 29.9 59.3 50.9 66.3 68.8 57.0 35.2 40.7 22.5 37.1 52.7 54.0 34.0 24.1 47.8 50.2 39.3 36.2 46.3 26.3 33.6 74.6 67.9 67.1 16.7 70.6 20.9 8.7 79.5 17.7 15.7 54.1 20.8 38.2 29.1 22.2 101.3 33.0 40.2 32.0 100.8 23.7 34.7 28.5 43.2 46.0 12.8 13.8 12.9 15.6 11.8 13.6 15.2 14.2 15.0 13.9 13.8 15.6 4.9 22.4 6.8 16.0 13.4 12.4 5.9 8.7 29.6 1.0 13.7 11.0 1.3 11.5 7.5 1.8 0.0 12.4 3.4 9.6 5.9 17.6 0.6 2.3 3.9 7.5 7.8 42.2 3.7 27.3 13.8 8.3 16.3 3.7 3.8 4.9 8.9 4.4 17.3 0.0 6.1 20.9 2.0 29.1 13.0 0.5 5.6 17.3 5.4 15.9 33.4 6.2 3.1 7.5 8.9 18.4 18.7 4.1 21.5 3.4 26.3 8.0 9.6 0.5 0.0 3.3 6.2 3.1 6.1 32.0 11.1 8.2 10.9 1.2 35.2 5.9 HBP1 ENSG00000105856 "HMG-box transcription factor 1" O60381 7 107168961-107202522 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 332.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020225, CAB032824" Approved Supported "Nuclear speckles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear speckles" "CAB032824: AB_2114615, HPA020225: " "unprognostic (9.00e-2)" "unprognostic (1.70e-1)" "unprognostic (1.06e-1)" "unprognostic (4.43e-1)" "unprognostic (4.79e-2)" "unprognostic (7.49e-3)" "unprognostic (1.99e-1)" "unprognostic (2.25e-2)" "unprognostic (3.47e-2)" "unprognostic (2.07e-2)" "unprognostic (2.99e-3)" "unprognostic (1.50e-1)" "prognostic favorable (7.70e-5)" "unprognostic (7.39e-2)" "unprognostic (2.31e-1)" "unprognostic (7.69e-2)" "unprognostic (5.26e-2)" 58.4 49.8 13.2 15.0 18.3 49.0 52.4 17.1 14.8 50.1 15.2 45.9 16.3 53.1 20.0 54.4 40.0 19.9 39.8 13.0 14.7 26.7 37.8 40.1 17.3 19.2 16.1 51.1 34.9 29.0 24.2 24.6 19.2 35.4 17.8 16.5 46.6 22.5 86.4 70.9 34.9 22.1 15.0 34.0 38.0 57.1 14.9 23.6 36.8 39.6 19.9 43.4 51.5 25.7 9.0 10.1 18.8 12.2 38.7 36.1 8.8 15.6 35.1 11.2 19.6 3.6 23.5 8.7 20.4 21.8 23.3 11.4 7.7 9.7 13.9 6.5 7.0 6.0 16.7 6.9 22.1 4.3 17.3 42.3 28.3 10.9 13.3 37.7 37.0 8.8 11.3 21.2 14.5 14.8 7.3 13.6 11.8 12.8 11.5 6.9 13.8 22.4 19.9 11.1 7.3 22.0 18.4 26.7 25.9 25.9 8.3 13.2 35.8 14.7 11.4 22.7 4.7 24.6 31.9 9.0 14.4 9.2 15.3 142.1 59.5 80.0 37.5 61.7 35.8 35.6 39.5 36.5 40.3 34.6 45.2 38.5 146.2 53.8 64.1 20.5 55.6 91.8 13.2 18.3 17.1 14.8 13.0 14.7 19.2 16.1 19.2 15.0 14.9 25.7 67.9 22.4 39.7 37.2 72.9 108.2 77.6 56.2 91.6 29.7 83.1 54.7 22.1 31.5 51.6 33.1 8.4 46.1 95.5 56.1 45.0 50.5 175.9 56.8 45.8 51.8 54.2 59.5 32.6 32.3 26.1 76.8 50.4 93.3 50.7 25.7 35.3 36.8 28.9 42.1 35.2 41.3 85.5 49.8 81.8 332.7 54.0 67.8 74.7 49.6 46.3 33.4 37.0 40.2 91.4 33.7 46.6 57.9 70.2 82.8 55.1 45.3 37.6 29.2 46.0 91.4 70.0 53.0 38.0 55.3 133.0 210.4 94.8 42.6 28.1 89.9 HBS1L "DKFZp434g247, EF-1a, eRF3c, ERFS, HBS1, HSPC276, KIAA1038" ENSG00000112339 "HBS1 like translational GTPase" Q9Y450 6 134960378-135103056 "Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis, Translation regulation" "Elongation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 198.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029728, HPA029729" Approved Approved "Nuclear bodies,Cytosol" NA NA 9200 "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 36: HEL - Hemostasis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear bodies, Cytosol" "HPA029728: AB_10611112, HPA029729: AB_10601228" "unprognostic (3.68e-3)" "unprognostic (6.39e-2)" "prognostic favorable (6.77e-4)" "unprognostic (1.26e-1)" "unprognostic (2.51e-2)" "unprognostic (1.14e-1)" "unprognostic (2.89e-2)" "unprognostic (8.66e-2)" "unprognostic (1.42e-1)" "unprognostic (1.79e-1)" "unprognostic (2.08e-1)" "unprognostic (1.23e-1)" "unprognostic (7.73e-2)" "unprognostic (3.84e-1)" "unprognostic (4.98e-2)" "unprognostic (1.47e-1)" "unprognostic (4.20e-2)" 35.3 32.5 29.7 31.2 51.8 82.5 39.7 37.9 48.1 31.8 23.6 29.9 23.0 31.8 23.0 43.9 29.9 26.6 50.9 28.3 44.6 36.9 63.1 24.5 40.3 41.2 34.7 32.6 39.5 47.1 17.1 35.4 43.0 28.7 29.5 44.8 42.3 29.4 167.2 26.9 26.9 38.5 33.2 23.5 29.6 32.8 39.4 65.5 38.6 123.4 43.4 34.0 20.0 87.1 63.9 41.9 85.7 124.8 76.7 67.9 65.4 125.5 107.7 116.7 143.6 70.7 46.8 109.5 55.3 111.9 84.3 46.6 121.1 92.4 181.2 111.8 82.9 335.3 113.6 95.5 91.9 209.5 87.9 67.8 68.7 111.0 135.0 87.2 98.5 128.2 182.7 89.4 125.1 60.0 129.6 53.0 55.4 75.6 45.3 120.0 95.3 74.9 72.3 59.7 84.2 57.4 85.6 88.7 88.4 67.4 74.1 124.6 93.6 82.4 85.5 103.3 134.8 202.5 158.3 184.8 125.5 106.8 104.9 108.7 47.8 52.0 44.0 44.9 48.9 49.3 51.2 44.2 55.9 42.7 68.9 57.0 22.0 66.4 44.9 44.6 67.5 57.7 29.7 51.8 37.9 48.1 28.3 44.6 41.2 34.7 43.0 33.2 39.4 87.1 25.9 25.6 25.7 27.1 32.0 27.3 26.9 23.2 31.3 42.7 22.1 17.8 56.0 17.2 30.4 11.0 14.6 32.2 36.8 11.1 25.4 25.2 36.3 27.1 28.9 24.4 16.3 58.0 61.4 20.4 33.7 26.2 20.4 27.1 60.0 23.9 18.2 39.3 13.5 21.9 56.2 11.1 16.2 18.0 18.9 12.6 18.6 17.6 30.2 29.0 28.0 26.5 19.6 47.3 198.7 18.7 12.3 22.2 53.7 21.6 13.9 23.5 24.0 26.6 39.5 36.6 25.9 28.3 25.8 24.9 18.6 40.5 34.5 27.5 14.6 25.7 HDAC7 "DKFZP586J0917, HDAC7A" ENSG00000061273 "Histone deacetylase 7" Q8WUI4 12 47782722-47833132 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 101.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 6.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 6.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004775 Supported Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA004775: AB_1850548" "unprognostic (3.83e-1)" "unprognostic (9.49e-3)" "unprognostic (1.37e-2)" "unprognostic (4.46e-2)" "unprognostic (6.56e-3)" "unprognostic (2.22e-2)" "unprognostic (2.50e-3)" "unprognostic (1.26e-1)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.28e-1)" "unprognostic (2.07e-1)" "unprognostic (2.38e-2)" "prognostic unfavorable (8.25e-4)" "unprognostic (6.24e-2)" "unprognostic (4.38e-2)" "unprognostic (9.69e-2)" "prognostic favorable (4.65e-4)" 52.5 41.8 7.7 28.5 8.1 23.6 45.3 3.2 9.7 46.2 24.6 44.2 8.9 51.4 13.6 23.5 50.3 16.8 31.6 4.1 4.8 29.3 6.0 55.0 27.3 17.2 7.1 44.9 14.5 20.1 20.6 19.5 10.2 34.4 4.8 2.8 30.6 17.1 16.2 40.1 28.6 16.9 3.4 38.4 27.2 7.9 10.7 80.0 39.2 9.4 15.2 44.3 38.5 7.6 41.6 28.1 28.6 46.9 21.9 60.2 25.3 39.4 30.7 28.3 18.8 37.4 38.4 80.5 126.8 37.1 13.9 37.8 6.7 31.4 10.5 38.8 13.6 27.6 29.9 8.6 23.6 9.1 1.2 39.4 10.8 28.6 15.4 51.6 58.6 45.9 29.9 33.4 18.6 18.0 83.2 21.8 39.4 9.1 29.1 64.2 14.7 29.6 12.1 26.9 8.1 18.8 30.6 14.1 14.4 18.4 13.4 12.0 66.6 56.9 61.0 47.6 28.9 70.8 58.8 67.4 23.8 41.9 19.1 0.0 1.4 0.0 0.8 0.5 0.9 0.8 0.7 0.7 0.4 0.5 0.8 0.6 6.5 0.9 0.5 0.3 0.3 1.5 7.7 8.1 3.2 9.7 4.1 4.8 17.2 7.1 10.2 3.4 10.7 7.6 80.6 41.7 32.1 34.9 32.7 13.8 26.8 28.7 8.6 20.3 22.5 17.4 13.4 28.6 28.6 36.8 0.0 4.8 18.6 5.3 1.9 31.6 15.5 26.2 39.4 79.3 7.3 40.4 19.9 23.0 3.5 37.8 25.5 58.4 8.8 20.2 101.7 2.0 15.6 28.6 17.5 9.6 24.4 32.7 14.1 6.9 55.0 13.3 14.2 46.9 20.5 11.7 28.8 10.6 13.6 66.8 7.3 33.1 42.9 69.1 0.6 3.8 31.8 4.0 26.3 18.3 26.9 1.1 3.7 10.3 21.6 2.9 28.2 9.3 8.1 46.8 HDGFL3 "Hdgfrp3, HRP-3" ENSG00000166503 "HDGF like 3" Q9Y3E1 15 83112738-83207823 "Predicted intracellular proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 96.9;Breast glandular cells: 34.3;Endometrial ciliated cells: 34.2;Endometrial stromal cells: 48.4;Granulosa cells: 41.4;Theca cells: 48.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 1.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040719 Approved Supported Nucleoplasm NA NA "Cluster 11: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA040719: AB_2677097" "unprognostic (1.28e-3)" "unprognostic (1.13e-1)" "unprognostic (3.52e-2)" "unprognostic (3.38e-2)" "unprognostic (1.53e-1)" "unprognostic (2.55e-2)" "unprognostic (1.91e-2)" "unprognostic (2.95e-2)" "unprognostic (2.99e-2)" "unprognostic (4.68e-2)" "unprognostic (1.93e-3)" "unprognostic (3.39e-2)" "unprognostic (1.73e-1)" "unprognostic (1.06e-2)" "unprognostic (3.55e-1)" "unprognostic (1.25e-1)" "unprognostic (1.85e-1)" 6.3 5.9 11.1 2.9 12.0 2.4 5.6 11.6 14.9 5.0 7.2 7.0 1.2 6.0 8.3 3.6 4.7 4.0 5.7 11.8 11.5 4.8 0.8 5.1 2.9 10.5 10.5 5.0 1.7 17.7 6.8 3.0 10.5 4.9 2.6 8.5 2.4 4.6 2.5 2.0 2.9 5.3 11.1 3.4 2.9 9.7 11.8 4.3 6.5 2.5 2.2 5.6 3.8 10.7 7.2 6.2 17.9 9.3 7.4 10.1 5.9 6.7 11.9 7.0 7.3 0.5 13.2 0.1 8.0 1.8 7.5 2.9 19.9 10.3 10.1 33.5 10.2 11.6 3.0 0.1 10.3 0.4 1.8 6.0 8.4 8.0 13.9 10.8 17.0 12.4 9.0 0.3 13.2 7.4 7.1 0.7 13.3 0.0 3.5 0.1 17.4 0.1 10.5 14.6 22.5 17.1 10.1 2.4 8.9 12.9 2.8 1.3 14.7 14.5 10.8 3.0 20.9 2.1 0.8 8.6 6.7 5.5 10.0 0.7 0.3 1.0 0.5 0.1 0.0 0.1 0.1 0.1 0.2 0.2 0.2 0.2 0.8 1.8 0.1 0.2 0.0 0.1 11.1 12.0 11.6 14.9 11.8 11.5 10.5 10.5 10.5 11.1 11.8 10.7 96.9 12.8 17.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 34.3 27.3 0.0 0.0 10.5 20.2 0.0 0.3 14.1 0.0 15.6 21.1 0.0 34.2 48.4 25.8 0.0 0.0 0.0 22.9 0.6 15.4 0.0 25.6 5.1 41.4 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 23.6 0.0 0.0 3.1 0.0 0.0 0.3 9.5 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.3 3.5 48.1 0.0 0.0 HDHD2 DKFZP564D1378 ENSG00000167220 "Haloacid dehalogenase like hydrolase domain containing 2" Q9H0R4 18 47107408-47150500 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040697, CAB045978, HPA059818" Approved Approved Vesicles NA NA 240000 "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB045978: AB_11124418, HPA040697: AB_2677084, HPA059818: AB_2684132" "unprognostic (3.22e-1)" "unprognostic (6.32e-2)" "unprognostic (9.95e-2)" "unprognostic (7.24e-2)" "unprognostic (1.11e-1)" "unprognostic (1.58e-1)" "unprognostic (3.11e-1)" "unprognostic (1.24e-1)" "unprognostic (2.10e-2)" "unprognostic (5.35e-3)" "unprognostic (1.82e-2)" "unprognostic (8.64e-3)" "prognostic favorable (3.52e-5)" "unprognostic (1.95e-1)" "unprognostic (1.61e-1)" "unprognostic (3.44e-1)" "unprognostic (1.17e-1)" 13.7 26.3 29.1 10.5 31.0 10.5 17.0 37.2 33.4 10.9 27.3 17.2 13.4 11.8 16.0 14.3 16.2 11.9 27.2 28.3 31.5 23.9 30.2 13.5 19.6 34.2 31.8 14.2 17.9 27.0 15.6 11.6 35.2 17.6 16.5 22.1 14.0 17.1 15.5 11.7 13.7 13.5 31.2 13.5 15.8 11.4 31.9 28.1 26.4 24.1 21.2 13.1 10.0 37.5 14.1 9.1 34.5 16.9 20.6 28.4 9.6 15.8 15.3 24.9 25.0 4.7 11.1 23.0 13.4 17.7 11.3 12.2 19.0 21.2 35.3 19.2 17.6 22.1 15.0 23.5 28.2 31.1 19.6 23.4 25.5 14.0 31.3 27.1 21.0 37.2 22.8 26.3 32.6 19.0 29.2 19.6 33.9 11.9 9.3 28.1 22.0 31.2 31.4 21.5 31.2 26.0 15.0 10.6 19.5 23.7 16.0 42.7 15.2 18.9 15.2 5.4 11.5 33.1 16.9 19.9 23.3 32.1 18.8 21.4 24.7 19.7 20.7 22.9 21.8 27.3 21.5 20.5 23.9 26.7 27.1 21.6 2.3 30.5 23.3 15.8 24.2 21.4 29.1 31.0 37.2 33.4 28.3 31.5 34.2 31.8 35.2 31.2 31.9 37.5 8.8 16.0 18.2 21.5 16.9 7.1 11.1 10.7 13.6 22.5 17.7 10.5 13.1 15.7 14.0 11.0 14.6 25.0 9.7 15.6 72.4 18.9 1.9 11.0 8.5 11.5 13.8 13.9 28.9 17.9 15.0 11.0 12.8 6.4 7.6 15.6 13.9 28.1 21.7 45.4 29.2 16.2 14.2 20.3 15.0 2.7 17.7 15.0 16.0 20.6 22.7 53.1 14.4 36.7 45.4 16.4 19.3 23.7 9.7 17.5 16.0 57.7 16.4 27.0 19.7 15.1 19.7 20.2 35.1 13.1 6.0 19.7 12.2 29.8 21.6 13.0 HEATR4 MGC48595 ENSG00000187105 "HEAT repeat containing 4" Q86WZ0 14 73478484-73558947 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.4;testis: 11.5" "Cell type enhanced" "Detected in some" "Astrocytes: 27.4;Early spermatids: 85.5;Excitatory neurons: 19.8;Inhibitory neurons: 16.9;Late spermatids: 29.3;Oligodendrocyte precursor cells: 13.0" "Not detected" "Not detected" "Region enriched" "Detected in some" 6 "cerebellum: 6.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 2.2;SCLC-21H: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003642, HPA079348" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 21: Non-specific - Transcription" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles Cytosol "HPA003642: AB_1079376, HPA079348: " "unprognostic (5.25e-2)" "unprognostic (2.45e-3)" "unprognostic (2.85e-2)" "unprognostic (1.36e-2)" "unprognostic (2.53e-2)" "unprognostic (2.60e-2)" "unprognostic (3.50e-1)" "unprognostic (8.09e-2)" "unprognostic (3.13e-1)" "unprognostic (1.51e-1)" "unprognostic (4.49e-2)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (3.28e-1)" "unprognostic (5.50e-2)" "unprognostic (1.96e-1)" "unprognostic (4.82e-3)" 0.5 0.5 0.2 0.8 0.2 0.9 0.4 6.4 1.0 0.7 0.0 0.4 1.9 1.0 0.3 0.6 0.6 0.8 0.6 0.8 0.0 0.4 0.8 0.5 1.6 0.0 0.0 1.0 0.9 0.2 0.5 0.3 0.1 0.4 0.1 2.9 0.8 0.1 1.9 3.6 0.8 0.1 0.0 1.0 0.7 11.5 0.1 0.0 1.0 0.0 0.0 0.3 0.5 0.8 0.7 0.8 0.3 0.5 0.0 0.0 0.3 0.3 0.0 0.0 0.1 0.2 0.2 0.8 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.2 0.1 0.6 0.1 0.0 0.0 0.5 1.0 0.0 0.0 0.1 0.0 0.5 0.0 0.8 0.2 0.2 0.0 2.2 0.2 0.9 0.3 0.2 0.7 0.4 0.4 0.3 0.0 1.1 2.4 0.3 0.8 1.1 1.2 0.5 1.3 0.1 0.4 0.1 0.9 0.7 0.1 0.6 0.2 0.1 0.5 0.2 0.1 0.2 0.1 0.1 0.4 0.1 0.2 0.5 0.5 0.3 0.0 0.6 0.5 0.5 0.3 0.3 0.0 0.2 0.2 0.1 0.2 0.2 6.4 1.0 0.8 0.0 0.0 0.0 0.1 0.0 0.1 0.8 0.2 0.0 1.5 27.4 0.2 0.3 0.5 0.1 0.0 0.8 0.3 0.3 0.8 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 85.5 0.3 0.3 0.4 0.0 0.0 19.8 0.0 0.2 0.5 0.0 0.9 0.0 0.4 0.0 0.6 0.1 0.0 16.9 0.2 0.0 0.0 1.0 29.3 0.6 0.3 0.0 3.7 0.0 0.6 0.0 13.0 6.8 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.0 0.9 0.7 11.1 1.6 0.0 0.9 0.1 0.4 0.1 0.0 0.1 HEG1 "HEG, KIAA1237" ENSG00000173706 "Heart development protein with EGF like domains 1" Q9ULI3 3 124965710-125055997 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 90.1;Cardiomyocytes: 90.5;Cone photoreceptor cells: 264.8;Endothelial cells: 121.5;Hepatic stellate cells: 130.3;Microglial cells: 92.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 174.1;HHSteC: 241.5;hTERT-RPE1: 351.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010952, HPA011559" Approved Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 510000000 "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Plasma membrane" "HPA010952: AB_2668389, HPA011559: AB_1850580" "unprognostic (1.10e-1)" "unprognostic (2.21e-1)" "unprognostic (6.52e-2)" "unprognostic (2.23e-1)" "unprognostic (1.30e-1)" "unprognostic (5.40e-2)" "unprognostic (6.48e-2)" "unprognostic (2.89e-2)" "unprognostic (2.36e-1)" "unprognostic (9.80e-2)" "unprognostic (1.69e-1)" "unprognostic (8.33e-2)" "prognostic unfavorable (1.93e-5)" "unprognostic (1.11e-2)" "unprognostic (4.99e-2)" "unprognostic (6.20e-3)" "prognostic unfavorable (1.16e-4)" 30.1 9.9 19.3 19.2 23.2 1.9 14.8 27.0 15.0 20.8 28.3 11.9 8.0 19.2 6.2 16.1 13.2 38.9 67.3 14.3 22.7 15.2 7.5 55.1 16.5 32.0 28.1 12.4 31.6 16.1 3.6 33.4 28.6 13.9 12.2 46.8 7.7 14.6 14.3 5.2 9.4 25.4 27.3 17.9 9.8 13.5 30.3 8.6 52.2 24.2 15.7 30.0 10.1 30.6 7.0 7.1 54.7 4.2 73.2 58.7 21.1 64.9 90.1 72.6 83.5 58.5 1.0 2.8 43.8 174.1 52.3 15.3 7.4 31.6 97.9 6.5 3.7 1.3 42.3 8.4 241.5 1.8 80.6 77.8 10.1 87.4 21.5 351.3 69.3 5.0 0.1 1.0 25.7 1.3 2.8 0.1 10.1 0.1 5.5 4.8 41.0 0.2 14.6 1.2 1.0 5.6 134.8 10.6 6.4 55.1 24.2 4.3 93.9 37.7 41.3 150.5 29.1 6.9 19.7 0.4 76.8 6.5 82.4 1.1 0.1 0.0 1.9 1.7 1.1 0.5 0.6 1.7 0.4 0.3 1.2 0.8 0.0 3.9 1.9 0.4 0.2 0.5 19.3 23.2 27.0 15.0 14.3 22.7 32.0 28.1 28.6 27.3 30.3 30.6 90.1 86.6 5.8 28.7 4.9 5.0 8.0 25.4 6.8 6.1 2.4 5.7 90.5 7.2 6.5 27.6 264.8 1.8 19.2 0.5 0.0 32.0 7.0 4.0 20.1 121.5 0.0 6.1 0.9 6.4 65.3 44.8 1.1 2.2 26.6 24.9 130.3 3.5 6.8 1.7 14.9 0.5 4.1 18.4 7.3 9.4 5.0 7.1 7.2 92.8 4.0 6.0 35.0 13.0 57.6 6.4 0.1 13.9 8.6 5.2 0.8 1.3 1.0 66.8 0.0 24.0 28.7 1.0 1.1 2.7 4.4 3.3 14.2 3.1 0.1 1.3 HGSNAT "FLJ32731, HGNAT, TMEM76" ENSG00000165102 "Heparan-alpha-glucosaminide N-acetyltransferase" Q68CP4 8 43140464-43202855 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Disease variant, Mucopolysaccharidosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029578 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "HPA029578: AB_10602423" "unprognostic (5.35e-2)" "unprognostic (4.61e-2)" "unprognostic (4.31e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (5.46e-4)" "unprognostic (3.94e-3)" "unprognostic (1.10e-1)" "unprognostic (6.54e-3)" "unprognostic (5.02e-2)" "prognostic favorable (6.33e-5)" "unprognostic (2.55e-2)" "unprognostic (5.48e-3)" "unprognostic (2.03e-1)" "unprognostic (1.27e-2)" "unprognostic (1.55e-1)" "unprognostic (1.72e-1)" "unprognostic (3.45e-2)" 32.3 20.0 13.1 17.5 13.0 21.7 27.8 10.6 13.5 35.0 13.8 25.4 18.4 30.1 30.6 24.0 29.0 25.9 23.3 13.3 17.6 20.0 26.6 24.5 11.7 13.3 12.0 35.9 29.9 22.7 30.7 28.4 13.2 26.9 17.2 12.5 25.9 23.3 14.4 35.4 20.9 25.1 11.4 17.6 23.2 7.6 15.8 11.3 26.9 17.6 15.7 25.2 28.7 13.0 27.4 36.0 8.9 18.0 71.7 53.8 13.3 30.5 36.2 21.8 19.3 5.1 39.2 14.8 20.5 42.9 15.2 15.5 4.0 18.5 12.7 6.4 6.9 16.3 22.2 8.1 23.0 3.7 2.5 36.2 25.9 11.7 24.9 34.5 39.2 7.0 7.5 22.1 40.4 10.0 14.8 7.2 8.0 16.3 5.4 1.6 16.1 7.7 36.1 22.8 4.7 14.0 39.0 12.6 17.4 19.0 43.7 20.9 46.3 33.2 5.4 20.9 12.7 17.9 18.2 6.1 26.8 6.3 20.8 0.2 8.8 9.4 2.7 5.4 3.0 1.9 2.3 2.8 15.8 2.1 1.7 1.9 3.2 8.8 8.6 2.0 1.7 5.0 13.1 13.0 10.6 13.5 13.3 17.6 13.3 12.0 13.2 11.4 15.8 13.0 39.1 16.0 31.9 48.0 26.7 18.0 19.5 22.6 8.6 50.6 23.9 21.7 10.5 28.6 17.8 51.5 50.1 39.2 30.1 27.2 3.9 26.7 0.5 23.5 42.1 37.8 24.1 15.3 61.8 28.1 39.4 34.3 32.6 36.5 8.2 51.2 49.6 23.5 29.2 25.2 76.3 28.0 18.3 34.3 58.8 3.2 35.1 43.3 19.6 44.0 33.5 13.5 34.0 50.8 43.8 29.9 17.0 31.6 19.8 20.7 31.4 9.9 23.5 39.6 26.3 30.2 28.2 1.1 3.0 22.3 21.2 30.1 25.0 37.4 21.7 17.7 HIBADH NS5ATP1 ENSG00000106049 "3-hydroxyisobutyrate dehydrogenase" P31937 7 27525442-27662883 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Branched-chain amino acid catabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 543.9;Proximal tubular cells: 355.1;Syncytiotrophoblasts: 272.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019522, HPA021002" Enhanced NA NA 820000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA019522: AB_1850690, HPA021002: AB_1850692" "unprognostic (6.76e-2)" "unprognostic (1.09e-1)" "unprognostic (7.50e-2)" "unprognostic (9.79e-2)" "unprognostic (1.72e-1)" "unprognostic (2.28e-3)" "unprognostic (7.22e-3)" "unprognostic (3.14e-2)" "unprognostic (1.10e-1)" "unprognostic (1.06e-1)" "unprognostic (1.73e-1)" "unprognostic (2.05e-2)" "prognostic favorable (5.56e-11)" "unprognostic (2.49e-2)" "unprognostic (5.47e-2)" "unprognostic (3.38e-2)" "unprognostic (3.39e-2)" 62.1 79.0 15.0 11.9 18.0 7.6 56.5 18.8 18.4 37.2 27.6 33.8 35.0 35.3 11.6 20.4 41.6 28.4 66.7 13.2 18.2 160.5 197.9 20.4 15.1 16.1 17.0 33.4 34.2 97.4 14.1 47.4 16.9 44.7 34.5 31.5 45.4 42.4 117.4 13.1 32.0 37.2 15.6 18.0 34.0 26.4 17.4 21.2 54.5 203.2 14.8 33.5 18.0 17.5 74.0 46.8 31.0 50.1 89.1 109.8 29.3 44.8 83.8 46.3 52.8 27.6 85.2 29.9 38.4 81.4 79.4 67.1 34.5 66.5 67.3 20.9 34.6 14.6 73.0 114.3 73.8 22.4 16.1 101.2 54.1 34.8 120.6 112.1 61.7 35.3 59.7 29.2 117.2 31.2 21.4 34.7 30.0 110.4 56.0 21.2 31.2 33.1 106.5 43.6 28.6 31.7 93.8 173.5 77.9 76.4 75.0 48.6 40.3 28.6 49.5 47.1 31.2 51.8 39.7 17.8 41.2 67.8 85.1 5.3 17.3 8.2 16.7 22.8 22.5 18.2 18.4 19.3 19.3 16.4 24.0 19.8 3.0 22.9 22.0 9.1 13.2 17.4 15.0 18.0 18.8 18.4 13.2 18.2 16.1 17.0 16.9 15.6 17.4 17.5 17.3 9.6 6.4 56.2 14.1 21.3 43.6 51.9 17.1 15.8 58.8 28.2 105.8 58.6 37.7 47.8 4.2 181.1 8.1 23.3 543.9 35.8 58.5 22.8 28.5 21.5 15.6 33.2 64.4 29.1 138.9 44.6 43.3 27.3 2.5 12.0 25.4 149.8 53.7 23.5 85.9 28.9 40.7 28.3 10.0 62.3 44.7 18.5 65.8 51.5 11.0 34.1 8.2 147.2 131.6 28.0 24.1 36.9 20.1 46.1 58.4 355.1 50.8 11.9 46.0 31.6 35.4 35.0 44.3 22.4 15.5 272.4 15.2 77.3 38.8 47.3 HINT1 "HINT, PKCI-1, PRKCNH1" ENSG00000169567 "Histidine triad nucleotide binding protein 1" P49773 5 131155383-131224468 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Hydrolase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 3537.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044577 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 2800000 "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 32: Non-specific - Translation" Cytosol "Nucleoplasm, Plasma membrane" "HPA044577: AB_10795618" "unprognostic (2.00e-1)" "unprognostic (9.27e-2)" "unprognostic (2.04e-2)" "unprognostic (1.03e-2)" "unprognostic (1.19e-1)" "unprognostic (1.35e-1)" "unprognostic (8.30e-3)" "unprognostic (2.48e-1)" "unprognostic (1.30e-2)" "unprognostic (6.49e-2)" "unprognostic (6.50e-3)" "unprognostic (4.43e-2)" "unprognostic (4.39e-3)" "unprognostic (2.08e-1)" "unprognostic (1.74e-1)" "unprognostic (1.67e-1)" "unprognostic (3.68e-1)" 132.6 175.0 235.7 139.8 245.1 259.3 172.7 241.6 326.2 117.6 243.8 227.6 176.1 119.6 187.5 181.3 165.6 108.0 167.2 245.9 247.8 256.7 474.2 119.0 206.5 241.6 237.2 121.5 165.5 285.6 152.5 87.5 249.1 155.1 226.5 110.8 172.8 116.4 334.1 170.0 196.3 124.2 242.6 126.9 136.5 80.1 240.8 166.5 177.2 278.4 192.3 152.9 129.7 245.3 437.1 522.7 448.2 877.2 273.1 297.1 441.3 300.3 230.9 235.4 272.1 547.1 516.8 563.3 625.7 329.6 569.1 253.4 315.4 635.3 244.1 500.0 514.6 199.1 814.0 771.9 532.6 349.4 65.4 400.1 618.6 295.8 528.2 533.7 314.1 727.8 313.4 1132.1 338.8 419.9 548.0 945.6 415.6 425.6 362.0 407.9 436.1 988.1 500.6 567.0 563.3 351.9 380.5 243.5 612.0 574.4 291.2 520.8 396.0 351.7 244.0 323.0 684.2 342.3 561.4 578.8 497.8 586.8 346.3 179.8 187.9 85.0 196.3 109.9 298.0 384.9 462.0 294.2 396.9 332.6 416.0 325.5 35.6 269.0 128.0 521.4 362.5 608.6 235.7 245.1 241.6 326.2 245.9 247.8 241.6 237.2 249.1 242.6 240.8 245.3 582.7 282.0 279.1 34.3 718.2 1301.2 1472.2 1928.1 889.5 191.2 1134.3 1831.1 517.0 1028.0 882.2 715.4 45.9 780.9 641.6 1245.1 1663.0 1024.5 783.0 718.9 443.7 501.2 698.1 669.7 53.8 774.3 1632.8 400.2 355.2 753.7 108.2 666.5 436.2 2380.1 887.1 148.0 48.0 947.2 915.5 472.4 906.9 206.3 392.4 447.0 965.8 34.7 1269.4 405.1 488.1 26.7 55.4 894.3 1094.2 418.6 679.7 1998.9 1690.3 3537.5 708.3 194.0 243.3 287.0 730.3 625.5 197.9 1109.1 1146.1 456.8 671.1 464.3 1280.4 1713.2 HK1 ENSG00000156515 "Hexokinase 1" P19367 10 69269984-69401884 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycolysis, Immunity, Inflammatory response, Innate immunity" "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Mental retardation, Neurodegeneration, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 374.0;Horizontal cells: 304.5;Late spermatids: 1034.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007043, HPA007044, CAB010052" Supported Supported Mitochondria NA NA 560000 "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "CAB010052: AB_627721, HPA007043: AB_1850652, HPA007044: AB_1079049" "unprognostic (8.80e-2)" "unprognostic (1.78e-1)" "unprognostic (2.03e-1)" "unprognostic (2.00e-3)" "unprognostic (1.15e-2)" "prognostic unfavorable (3.39e-6)" "unprognostic (1.23e-1)" "unprognostic (1.97e-1)" "unprognostic (4.29e-2)" "unprognostic (1.16e-1)" "unprognostic (3.93e-3)" "unprognostic (1.12e-1)" "unprognostic (1.37e-3)" "unprognostic (7.25e-2)" "unprognostic (1.40e-2)" "unprognostic (2.00e-3)" "unprognostic (3.86e-2)" 47.0 24.4 61.0 45.0 65.7 60.3 40.6 58.0 76.6 54.7 64.2 60.1 13.1 41.3 11.2 129.9 37.0 25.7 150.8 69.1 62.7 49.2 8.5 48.1 34.1 56.7 59.8 19.9 12.3 25.0 44.9 49.3 71.1 52.9 31.9 147.6 67.1 53.1 193.5 102.6 29.2 49.8 40.0 40.3 61.6 77.2 53.5 44.9 71.0 146.7 47.6 74.3 80.9 54.1 101.6 56.6 74.2 71.1 81.0 60.4 47.1 98.3 256.5 128.5 138.0 16.3 11.0 7.3 75.8 165.9 92.9 86.2 69.9 220.0 122.0 67.5 54.5 250.0 58.3 1.1 91.7 5.1 181.2 91.5 125.8 184.5 407.6 160.8 135.4 36.8 424.5 51.3 178.7 167.7 29.7 13.1 113.8 51.7 247.0 44.8 45.0 0.6 88.7 117.4 75.7 88.7 112.6 215.4 65.2 104.3 117.7 16.5 140.4 190.5 86.4 106.5 139.6 61.1 42.8 17.4 247.3 130.4 56.1 68.7 88.8 44.6 41.5 125.2 69.0 33.5 47.9 47.6 81.0 19.9 41.7 33.9 20.9 31.2 135.4 9.1 58.1 110.4 61.0 65.7 58.0 76.6 69.1 62.7 56.7 59.8 71.1 40.0 53.5 54.1 26.1 25.6 32.4 38.2 26.5 48.3 50.5 37.8 43.9 83.9 33.1 21.7 130.6 4.3 34.2 27.6 54.2 70.6 14.6 30.3 13.7 28.6 374.0 32.6 28.0 37.9 18.7 104.8 53.8 30.6 93.3 30.3 41.3 34.5 23.4 72.6 26.7 1.1 49.4 304.5 49.8 28.7 44.7 41.7 21.9 1034.1 15.2 51.3 37.4 29.0 35.3 32.9 20.6 14.1 3.5 54.6 11.1 18.4 19.1 29.1 0.7 1.1 30.7 95.5 19.7 22.2 43.1 5.3 6.2 86.0 51.7 118.9 30.5 28.3 19.3 43.5 HLX "HB24, HLX1" ENSG00000136630 "H2.0 like homeobox" Q14774 1 220879431-220885059 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 86.5" "Cell type enhanced" "Detected in many" "Adipocytes: 35.7;Endothelial cells: 32.5;Hepatic stellate cells: 47.5;Hofbauer cells: 34.1;Kupffer cells: 24.8;Langerhans cells: 23.5;monocytes: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 65.1;neutrophil: 55.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 65.1" "Cell line enhanced" "Detected in many" "SK-MEL-30: 32.4;THP-1: 100.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA005968 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "HPA005968: AB_1079066" "unprognostic (6.18e-2)" "unprognostic (1.38e-1)" "unprognostic (1.88e-3)" "unprognostic (2.57e-2)" "unprognostic (9.19e-3)" "unprognostic (1.76e-1)" "unprognostic (1.40e-1)" "unprognostic (5.14e-3)" "unprognostic (1.06e-1)" "unprognostic (9.73e-2)" "unprognostic (3.19e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (7.28e-6)" "unprognostic (8.44e-3)" "unprognostic (3.68e-2)" "unprognostic (1.15e-1)" "unprognostic (1.36e-1)" 35.2 4.7 1.4 10.3 1.3 86.5 18.6 1.4 2.0 7.5 1.5 44.4 4.8 5.5 0.5 3.9 9.3 9.6 18.9 2.0 1.6 6.8 21.8 23.1 8.5 1.9 1.7 4.2 4.3 1.3 3.0 13.8 2.0 6.3 2.0 0.0 3.5 0.4 9.2 8.7 18.9 5.6 1.9 15.7 5.2 1.8 2.6 2.1 9.5 4.2 2.3 11.0 8.8 1.9 0.0 2.1 0.0 3.2 9.2 14.7 3.0 11.4 18.9 12.8 10.6 0.2 0.3 0.0 0.1 6.8 2.5 0.0 0.5 0.0 5.3 3.0 5.9 0.0 1.1 0.3 15.1 3.9 0.8 15.4 0.2 14.7 0.8 1.1 5.7 0.0 4.0 0.0 1.6 0.0 0.0 10.3 0.3 0.0 5.2 0.3 9.0 0.1 0.8 0.1 0.0 2.4 0.7 0.0 32.4 0.1 0.0 100.4 1.8 8.7 0.0 1.3 9.3 0.0 0.0 0.0 14.1 12.3 3.6 65.1 10.4 22.3 0.0 3.4 0.0 5.7 0.0 0.0 13.0 2.7 0.0 0.0 55.9 0.7 0.7 8.7 0.4 3.3 1.4 1.3 1.4 2.0 2.0 1.6 1.9 1.7 2.0 1.9 2.6 1.9 35.7 9.6 5.3 1.0 4.3 2.8 0.1 0.0 0.6 0.1 0.5 1.3 5.7 0.0 0.0 0.0 0.0 0.6 3.0 0.4 0.0 0.5 0.5 0.2 2.6 32.5 0.0 8.4 0.3 0.4 0.7 8.4 0.5 0.3 3.8 0.1 47.5 10.8 34.1 0.0 0.2 0.3 0.0 24.8 23.5 0.4 2.5 17.8 0.0 4.7 44.2 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.2 0.2 0.0 0.1 0.0 0.0 6.6 7.5 10.6 0.1 2.2 0.3 3.1 0.4 1.1 0.4 0.3 0.4 HMBOX1 "FLJ21616, HNF1LA, HOT1, PBHNF" ENSG00000147421 "Homeobox containing 1" Q6NT76 8 28890395-29064764 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 20.0" "Cell type enhanced" "Detected in all" "Astrocytes: 125.7;Oligodendrocyte precursor cells: 118.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055855, HPA058586, CAB070418" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 14: Monocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "Nuclear bodies, Cytosol" "CAB070418: AB_11154826, HPA055855: AB_2682945, HPA058586: AB_2683764" "unprognostic (2.68e-3)" "unprognostic (2.30e-3)" "unprognostic (4.52e-2)" "unprognostic (1.41e-1)" "unprognostic (1.85e-1)" "unprognostic (1.03e-3)" "unprognostic (1.20e-1)" "unprognostic (2.75e-3)" "unprognostic (1.49e-1)" "unprognostic (4.25e-2)" "unprognostic (1.89e-2)" "unprognostic (1.65e-1)" "unprognostic (1.51e-1)" "unprognostic (3.84e-2)" "unprognostic (2.81e-1)" "unprognostic (1.02e-1)" "unprognostic (1.47e-1)" 4.6 6.7 7.6 5.1 11.9 10.8 4.2 10.6 5.7 3.7 1.7 3.8 3.1 4.4 3.0 3.2 3.7 4.2 4.5 5.3 17.9 4.3 4.2 4.6 5.3 15.0 20.0 6.1 3.3 5.0 1.8 6.8 15.6 2.9 3.9 6.2 3.1 2.5 2.8 4.4 4.3 5.2 10.4 5.7 4.3 7.6 11.6 4.9 6.2 3.7 5.9 3.8 2.4 12.9 6.2 6.8 7.1 8.2 6.5 6.7 6.0 2.6 3.5 4.0 4.3 3.1 3.9 15.1 6.3 4.5 6.0 5.3 14.4 5.3 5.6 5.5 2.4 15.6 13.8 4.2 5.3 5.4 10.2 3.3 7.5 5.3 10.1 4.9 9.1 9.0 22.7 14.4 5.7 3.8 9.9 2.7 5.0 6.6 1.6 8.1 7.1 3.4 2.8 11.5 3.0 9.2 5.1 3.9 5.4 5.9 3.9 4.8 13.0 3.6 16.8 3.9 3.8 4.4 4.8 5.9 4.6 6.5 5.4 3.2 2.4 1.1 1.9 2.6 2.7 3.4 1.9 1.8 2.5 2.6 2.4 2.4 1.4 1.2 4.7 1.9 0.8 1.4 7.6 11.9 10.6 5.7 5.3 17.9 15.0 20.0 15.6 10.4 11.6 12.9 25.5 16.0 18.1 125.7 30.3 16.7 15.8 18.1 15.9 24.4 15.3 10.5 23.6 20.0 14.0 29.5 39.6 12.9 18.7 16.2 15.6 8.3 93.0 15.0 21.2 34.2 17.4 19.6 90.1 14.4 14.1 19.2 11.2 29.4 17.1 36.7 68.6 13.7 10.3 30.3 109.8 12.9 22.4 19.8 36.4 31.5 35.8 20.1 16.0 91.8 21.4 28.3 26.8 118.1 111.8 14.1 11.3 31.6 14.4 21.0 20.4 8.8 14.3 31.6 19.7 34.6 17.3 43.6 15.2 10.1 19.7 19.2 22.8 19.5 14.7 22.6 HMGB1 "DKFZp686A04236, HMG1, HMG3, SBP-1" ENSG00000189403 "High mobility group box 1" P09429 13 30456704-30617597 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Autophagy, Chemotaxis, DNA damage, DNA recombination, DNA repair, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003506, CAB005873, HPA073663" Supported Supported Nucleoplasm "Secreted to blood" NA NA 2800000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB005873: AB_444360, HPA003506: AB_1079070, HPA073663: " "unprognostic (9.56e-2)" "unprognostic (1.34e-1)" "unprognostic (1.97e-2)" "unprognostic (1.07e-1)" "unprognostic (4.44e-2)" "unprognostic (4.29e-2)" "unprognostic (3.16e-2)" "unprognostic (4.33e-2)" "unprognostic (5.73e-2)" "unprognostic (1.73e-1)" "unprognostic (2.64e-2)" "unprognostic (2.30e-2)" "unprognostic (4.28e-3)" "unprognostic (5.22e-3)" "unprognostic (4.67e-1)" "unprognostic (9.13e-3)" "unprognostic (1.97e-2)" 312.0 224.3 266.2 355.1 282.2 1021.3 318.2 267.6 362.4 319.0 227.0 327.8 281.9 363.6 270.1 297.0 265.5 227.0 242.2 250.1 282.9 243.7 360.8 242.2 664.8 281.5 273.3 254.9 189.3 226.1 163.3 252.1 286.2 265.9 381.2 174.8 224.5 280.1 388.5 244.2 309.2 319.5 277.7 284.9 269.0 153.9 269.9 900.3 267.4 364.7 738.9 282.7 274.1 308.2 816.7 617.4 1402.5 1054.0 384.5 380.1 551.4 1012.6 547.9 957.3 643.5 983.6 1328.6 1639.3 515.5 924.0 880.6 886.5 1484.7 817.4 1639.6 869.6 622.4 1727.4 455.4 913.5 210.3 2513.6 1009.8 253.4 426.0 713.3 656.6 497.8 1302.2 1350.8 1167.9 571.7 855.6 1508.3 3224.3 2682.1 1184.3 1424.3 683.7 2673.3 1927.8 965.8 908.1 792.8 1264.0 1139.8 928.6 682.0 541.0 672.3 668.5 1857.9 814.7 637.2 921.8 689.7 1197.1 513.9 714.8 3508.3 261.1 1634.0 1369.3 1036.6 503.7 926.1 467.3 410.9 522.1 582.6 532.3 530.7 520.1 590.7 477.4 459.7 631.7 615.4 411.0 512.5 702.6 1072.0 266.2 282.2 267.6 362.4 250.1 282.9 281.5 273.3 286.2 277.7 269.9 308.2 948.9 458.3 496.6 188.4 920.7 791.1 986.7 942.7 752.4 414.3 471.9 630.0 172.5 561.9 561.3 603.2 131.3 998.9 759.9 408.1 766.9 941.3 113.4 611.2 1040.2 766.0 423.0 1808.9 58.5 967.2 1441.4 676.5 486.3 728.3 546.8 772.2 589.0 749.5 728.8 196.9 47.2 675.6 710.1 549.9 884.4 107.2 720.1 694.2 674.1 81.5 578.7 609.9 879.5 99.5 149.3 1212.3 554.8 666.9 1252.9 811.2 506.7 827.5 418.7 252.8 650.8 588.9 1005.9 549.1 1211.0 1045.8 691.9 465.7 797.9 515.7 839.1 867.9 HMGN3 TRIP7 ENSG00000118418 "High mobility group nucleosomal binding domain 3" Q15651 6 79201245-79234738 "Predicted intracellular proteins" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018370, HPA027971, HPA063572" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm Cytosol "CAB018370: , HPA027971: AB_1850808, HPA063572: AB_2732703" "unprognostic (1.02e-1)" "unprognostic (2.04e-2)" "unprognostic (5.92e-2)" "unprognostic (5.26e-2)" "unprognostic (3.48e-1)" "unprognostic (3.88e-2)" "unprognostic (5.24e-2)" "prognostic favorable (2.76e-4)" "unprognostic (8.78e-2)" "unprognostic (5.31e-3)" "unprognostic (1.47e-3)" "unprognostic (5.81e-2)" "prognostic unfavorable (1.02e-7)" "unprognostic (1.70e-2)" "unprognostic (1.09e-1)" "unprognostic (2.69e-1)" "unprognostic (6.43e-3)" 92.4 174.4 132.9 69.5 136.2 72.8 116.1 141.8 190.4 82.2 153.6 100.6 90.4 93.6 168.6 95.1 209.3 82.8 227.2 132.9 135.8 168.4 147.5 111.5 127.1 139.5 135.2 105.5 90.3 116.7 152.0 114.6 140.8 84.7 73.4 164.6 154.3 68.0 151.4 81.1 74.1 76.1 136.6 91.5 106.9 83.2 133.7 112.7 113.2 130.1 109.9 77.1 81.9 145.6 101.7 90.3 309.7 135.0 121.9 99.6 70.1 69.0 73.7 75.6 110.3 508.3 83.9 1.2 124.2 56.5 101.0 63.4 203.6 78.3 74.2 298.7 170.9 355.9 292.3 268.9 78.0 294.9 52.3 121.5 85.4 50.3 27.7 72.9 170.9 74.3 212.3 275.0 123.8 92.9 136.3 564.7 227.8 87.7 224.5 229.7 472.6 103.8 525.3 145.3 126.0 168.5 131.3 149.4 102.4 271.1 85.1 488.6 75.0 20.9 91.7 73.5 155.3 235.3 375.2 1.9 11.8 1.1 103.0 38.3 147.3 13.6 107.8 148.0 95.9 112.9 75.7 92.8 179.2 99.8 88.7 106.8 7.2 142.3 143.9 208.6 90.4 169.3 132.9 136.2 141.8 190.4 132.9 135.8 139.5 135.2 140.8 136.6 133.7 145.6 140.6 96.1 167.9 129.9 110.1 171.1 193.7 516.8 234.5 261.8 301.4 376.3 424.5 231.6 373.7 242.8 75.0 940.6 169.9 35.3 602.6 229.3 72.5 775.8 108.1 166.0 272.9 95.4 115.8 198.6 823.7 165.3 116.2 199.2 109.6 80.9 261.3 256.3 309.7 195.2 105.3 131.1 435.4 186.0 206.5 60.9 187.0 148.4 257.9 58.1 403.3 320.2 198.8 66.9 159.7 107.2 52.4 167.0 211.3 85.3 36.5 852.5 900.3 134.3 144.7 102.4 233.9 26.8 52.0 260.0 149.9 555.3 109.9 232.4 121.5 173.2 HOMER3 HOMER-3 ENSG00000051128 "Homer scaffold protein 3" Q9NSC5 19 18929201-18941261 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 125.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 76.4;Muller glia cells: 72.6;Proximal tubular cells: 84.2;Theca cells: 322.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 15.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NB-4: 353.6;THP-1: 420.0;U-266/84: 375.4" "Region enriched" "Detected in all" 6 "cerebellum: 189.2" "Low region specificity" "Detected in all" "CAB032656, HPA040999, CAB079015" Enhanced Supported Supported "Plasma membrane,Cytosol,Cytoplasmic bodies" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Cytosol "Plasma membrane, Cytoplasmic bodies" "CAB032656: AB_2120801, CAB079015: , HPA040999: AB_2677242" "unprognostic (3.41e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (4.24e-5)" "unprognostic (1.19e-1)" "unprognostic (2.06e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (4.93e-5)" "unprognostic (1.07e-1)" "unprognostic (8.88e-2)" "unprognostic (5.78e-2)" "unprognostic (1.28e-1)" "unprognostic (2.10e-2)" "unprognostic (5.99e-2)" "unprognostic (3.76e-2)" "unprognostic (2.33e-1)" "unprognostic (1.41e-1)" "unprognostic (4.11e-2)" 33.1 29.6 33.3 9.9 41.9 22.3 26.2 76.9 44.6 31.7 41.1 27.0 7.0 24.6 6.4 15.3 16.7 16.5 25.0 40.4 35.1 52.2 6.1 25.6 7.9 42.3 40.9 20.1 12.4 37.5 8.6 14.7 42.8 21.9 6.0 5.9 27.6 9.4 114.5 35.4 14.4 10.6 39.4 125.1 17.0 9.2 41.6 7.4 49.3 18.6 3.8 29.7 26.0 45.5 112.1 28.5 53.1 44.4 48.3 48.6 26.2 108.1 94.9 106.4 53.4 14.6 41.8 0.9 49.9 122.1 76.1 68.6 18.4 140.4 58.9 4.0 11.0 0.1 9.7 27.5 44.9 21.5 1.7 39.3 89.4 59.0 79.1 113.0 130.3 7.9 3.2 28.6 78.1 30.3 1.9 353.6 27.3 6.1 115.5 55.2 16.2 53.4 38.2 28.3 0.2 44.8 26.6 31.2 78.5 10.2 14.0 420.0 105.3 94.0 42.0 114.5 132.2 274.2 375.4 93.6 148.0 270.6 69.8 0.1 15.0 2.9 0.1 5.3 0.0 2.3 0.8 0.3 1.3 2.7 0.1 0.0 5.8 0.0 1.6 0.2 0.8 4.2 33.3 41.9 76.9 44.6 40.4 35.1 42.3 40.9 42.8 39.4 41.6 45.5 21.7 3.2 0.0 9.4 9.3 11.9 22.4 24.4 6.8 2.2 14.3 22.5 4.1 2.8 8.0 12.9 0.0 1.0 0.6 0.1 11.7 22.9 2.0 4.3 18.7 38.0 1.8 0.4 0.3 13.6 2.4 20.5 0.0 6.3 10.2 34.8 21.8 0.7 76.4 1.7 3.9 0.9 22.4 16.2 7.6 1.7 13.7 32.2 12.4 1.9 8.3 72.6 0.0 1.0 13.4 42.0 0.0 10.9 13.8 25.2 0.0 84.2 3.6 4.1 0.0 14.4 27.8 4.7 6.7 4.2 14.5 1.1 2.5 322.4 0.3 21.4 HOXA5 "HOX1, HOX1C" ENSG00000106004 "Homeobox A5" P20719 7 27141052-27143681 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 80.9;epididymis: 49.0;fallopian tube: 49.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 99.6;Breast myoepithelial cells: 27.2;Proximal tubular cells: 27.1;Squamous epithelial cells: 46.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 51 "medulla oblongata: 38.3;pons: 10.5;spinal cord: 24.6;white matter: 16.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 94.2;HEK 293: 160.4;RPTEC TERT1: 36.2" "Region enriched" "Detected in single" 220 "pons and medulla: 22.0" "Group enriched" "Detected in some" 33 "medulla oblongata: 4.4;spinal cord: 16.3" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (2.43e-1)" "unprognostic (3.98e-3)" "unprognostic (2.99e-1)" "prognostic unfavorable (2.28e-4)" "unprognostic (1.87e-1)" "unprognostic (7.80e-2)" "unprognostic (4.07e-2)" "unprognostic (1.83e-1)" "unprognostic (6.02e-2)" "unprognostic (5.54e-2)" "unprognostic (2.31e-1)" "unprognostic (5.47e-2)" "unprognostic (3.00e-2)" "unprognostic (4.37e-2)" "unprognostic (3.26e-2)" "unprognostic (3.47e-3)" "unprognostic (2.00e-1)" 16.8 80.9 0.2 3.0 0.1 3.1 11.6 0.2 0.4 7.1 0.0 18.7 2.7 12.3 49.0 5.2 49.4 0.9 0.2 0.1 0.1 25.5 0.8 19.9 1.8 38.3 0.4 2.9 1.4 3.3 0.0 0.2 10.5 8.6 6.9 0.0 0.0 9.8 6.7 7.8 13.7 6.2 24.6 3.3 11.7 0.6 0.0 0.5 1.1 0.3 0.1 11.8 4.6 16.6 5.7 2.8 0.0 94.2 0.1 0.0 0.4 1.6 1.2 1.7 1.5 1.7 9.7 3.1 13.5 3.0 2.0 7.6 5.3 0.4 1.7 1.4 160.4 2.2 1.2 5.7 0.9 3.6 2.5 10.3 0.5 3.1 5.4 0.0 20.8 5.5 0.4 0.0 3.2 1.7 0.0 1.1 0.0 2.1 2.9 13.4 0.4 0.0 36.2 7.6 10.9 0.1 7.2 0.0 3.6 0.3 1.1 1.3 8.3 0.3 1.2 5.6 3.9 0.0 0.1 3.3 0.7 10.8 10.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.6 0.1 0.1 0.0 0.0 0.2 0.1 0.2 0.4 0.1 0.1 38.3 0.4 10.5 24.6 0.0 16.6 9.3 0.0 1.1 0.0 0.9 3.4 6.4 0.1 99.6 0.0 17.3 27.2 8.0 0.0 0.0 0.0 0.0 0.0 2.8 17.0 7.9 0.1 0.0 0.9 19.7 8.4 9.0 2.5 0.0 0.0 0.0 11.5 2.6 0.4 0.0 0.0 21.0 0.0 0.6 0.0 0.0 10.8 0.0 2.5 1.5 0.3 0.3 9.2 1.8 0.0 0.7 0.0 0.0 0.0 0.0 0.0 15.5 0.0 1.0 2.2 9.6 27.1 0.1 0.0 0.0 4.5 14.3 0.9 0.7 46.7 2.8 0.1 1.7 0.2 18.8 6.3 HPR ENSG00000261701 "Haptoglobin-related protein" P00739 16 72063148-72077246 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 811.9" "Group enriched" "Detected in some" 14 "Hepatocytes: 503.0;Smooth muscle cells: 128.8" "Cancer enriched" "Detected in some" 53 "liver cancer: 185.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "Hep G2: 50.6" HPA047750 Supported Approved Vesicles "Secreted to blood" NA NA 49000000000 55000000000 "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA047750: AB_2680146" "unprognostic (2.43e-1)" "unprognostic (4.69e-2)" "unprognostic (5.97e-3)" "unprognostic (2.42e-1)" "unprognostic (2.32e-3)" "unprognostic (2.36e-1)" "unprognostic (1.66e-1)" "unprognostic (8.21e-2)" "unprognostic (2.30e-1)" "unprognostic (3.44e-6)" "unprognostic (2.09e-2)" "unprognostic (1.45e-1)" "unprognostic (1.29e-1)" 5.5 0.5 14.1 0.2 15.3 0.1 2.0 13.9 16.7 1.2 11.3 1.2 0.6 0.3 0.4 0.3 1.3 0.7 137.2 13.7 14.3 4.0 811.9 1.5 0.7 14.4 14.3 2.0 0.6 0.0 0.3 0.0 13.6 1.6 0.1 0.8 0.3 0.3 1.7 0.6 1.1 0.1 12.8 0.3 1.7 1.9 15.2 0.2 1.1 0.2 0.1 0.4 1.9 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.6 2.2 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.1 0.1 0.1 0.0 0.2 0.4 0.2 0.0 0.1 0.0 0.6 0.6 0.0 14.1 15.3 13.9 16.7 13.7 14.3 14.4 14.3 13.6 12.8 15.2 13.1 0.0 0.0 7.5 2.3 0.4 0.1 0.0 0.9 0.0 0.1 0.0 0.0 22.4 12.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.8 0.0 5.3 0.2 0.2 0.0 2.6 0.0 0.0 0.0 1.1 10.8 503.0 0.0 0.0 0.2 0.0 2.0 12.8 0.0 2.8 9.9 0.0 0.0 0.0 0.0 4.9 0.0 0.0 1.2 0.0 0.0 5.3 0.0 0.0 0.0 13.0 0.2 0.1 0.0 6.1 128.8 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.2 0.0 HRH1 ENSG00000196639 "Histamine receptor H1" P35367 3 11137093-11263557 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 46.1;Distal enterocytes: 44.9;Glandular and luminal cells: 41.6;Suprabasal keratinocytes: 41.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029740 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Cytosol "HPA029740: AB_10601578" "unprognostic (4.60e-3)" "unprognostic (3.41e-2)" "unprognostic (6.37e-3)" "unprognostic (9.55e-2)" "unprognostic (3.32e-2)" "unprognostic (1.07e-2)" "unprognostic (9.60e-3)" "unprognostic (4.00e-3)" "unprognostic (7.54e-2)" "unprognostic (4.98e-2)" "prognostic unfavorable (1.27e-5)" "unprognostic (1.43e-1)" "unprognostic (1.70e-2)" "unprognostic (1.66e-1)" "unprognostic (3.13e-2)" "unprognostic (7.19e-2)" "unprognostic (1.20e-1)" 5.7 3.0 5.5 3.1 6.2 0.1 3.4 1.7 6.5 5.0 2.1 8.8 2.7 4.3 4.8 3.3 7.4 7.1 1.5 6.1 5.3 4.2 0.7 4.1 1.2 4.6 2.9 5.9 0.6 0.9 0.5 3.9 3.6 2.4 5.1 0.2 1.8 3.5 0.9 5.1 4.3 5.4 3.2 1.0 1.7 0.8 5.8 1.2 1.2 2.2 1.4 14.3 5.0 4.1 2.6 6.1 0.0 0.0 2.7 28.5 4.2 4.6 15.3 13.3 8.8 1.1 21.8 0.0 13.4 10.6 13.5 17.3 0.0 6.3 17.7 10.1 0.0 1.4 9.7 0.0 8.4 4.5 2.4 10.0 3.7 30.4 10.5 18.4 19.1 0.2 0.0 0.1 5.8 0.0 0.0 1.9 0.0 2.6 5.4 0.4 1.6 0.6 23.2 3.6 0.2 0.0 6.6 4.6 0.0 0.2 0.0 3.5 28.8 14.8 9.4 15.3 23.4 0.0 1.7 0.1 22.5 3.9 13.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 5.5 6.2 1.7 6.5 6.1 5.3 4.6 2.9 3.6 3.2 5.8 4.1 11.5 6.4 1.1 33.3 0.1 46.1 8.9 7.4 6.8 0.0 0.5 0.5 0.5 0.0 19.3 1.8 0.0 0.2 0.0 44.9 0.0 0.6 0.3 20.5 6.9 20.2 3.5 0.0 34.6 0.7 1.0 16.7 8.6 41.6 2.5 28.8 2.5 0.0 27.2 0.0 19.1 15.1 4.1 12.5 12.3 0.2 3.7 9.8 0.0 2.8 0.1 0.0 0.0 2.0 1.1 14.0 21.0 0.0 0.0 6.2 29.1 0.7 5.0 0.2 0.0 6.8 2.8 1.8 3.3 2.2 41.5 0.5 1.0 0.2 15.8 19.3 HRH2 ENSG00000113749 "Histamine receptor H2" P25021 5 175658030-175710756 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.0;heart muscle: 26.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 26.2;Excitatory neurons: 62.2;Inhibitory neurons: 19.1;Kupffer cells: 29.4;Macrophages: 36.2;monocytes: 24.3;Smooth muscle cells: 33.6" "Group enriched" "Detected in many" 5 "melanoma: 2.9;renal cancer: 4.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 134.4;neutrophil: 161.7" "Group enriched" "Detected in many" 5 "granulocytes: 161.7;monocytes: 51.6" "Group enriched" "Detected in some" 4 "RPMI-8226: 65.6;SK-MEL-30: 19.2;THP-1: 18.0;U-937: 21.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA013770 Approved NA NA "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA013770: AB_1851086" "unprognostic (8.56e-3)" "unprognostic (1.62e-1)" "unprognostic (6.66e-2)" "unprognostic (5.96e-2)" "unprognostic (3.49e-2)" "unprognostic (1.80e-1)" "unprognostic (1.20e-1)" "unprognostic (4.77e-2)" "unprognostic (9.93e-2)" "unprognostic (5.76e-2)" "unprognostic (1.52e-1)" "unprognostic (2.35e-1)" "unprognostic (3.71e-3)" "unprognostic (2.01e-2)" "unprognostic (1.97e-2)" "unprognostic (1.97e-3)" "unprognostic (1.77e-2)" 7.6 1.5 4.5 12.0 14.4 37.0 3.0 1.1 9.6 5.1 0.5 1.4 6.2 2.2 0.9 1.4 2.9 2.5 26.3 5.3 1.4 2.3 1.0 7.2 3.8 1.2 1.6 1.1 1.5 1.3 0.8 10.2 1.1 4.7 1.1 0.3 1.4 4.6 0.8 2.2 6.4 3.6 1.7 18.0 19.5 0.5 3.9 8.5 1.5 1.5 3.1 4.1 2.0 5.1 0.0 1.5 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.1 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.0 0.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 5.0 2.9 0.0 0.0 7.1 0.0 65.6 0.0 0.3 0.5 0.0 0.0 0.0 19.2 1.7 0.1 18.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 21.6 4.3 134.4 45.8 52.8 0.2 44.9 0.3 0.0 3.8 1.0 23.5 0.1 7.9 4.8 161.7 2.1 51.6 18.3 3.3 15.3 4.5 14.4 1.1 9.6 5.3 1.4 1.2 1.6 1.1 1.7 3.9 5.1 1.1 0.0 2.5 1.0 1.0 0.8 0.1 0.0 0.6 9.3 3.7 0.9 26.2 0.0 2.5 0.0 0.0 0.1 8.4 0.0 0.0 0.0 0.6 0.1 0.8 1.9 0.0 3.0 62.2 2.4 0.2 3.3 7.1 0.1 2.5 3.0 0.0 0.2 11.8 1.7 19.1 0.6 0.0 29.4 8.5 1.0 0.0 36.2 0.0 10.3 24.3 0.1 0.0 1.5 1.7 0.3 0.0 0.4 0.3 0.2 0.6 0.3 0.7 0.2 0.0 0.1 33.6 0.2 0.9 0.1 0.3 0.0 4.7 0.1 0.5 0.0 HSCB "DNAJC20, HSC20, Jac1" ENSG00000100209 "HscB mitochondrial iron-sulfur cluster cochaperone" Q8IWL3 22 28742039-28757515 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018447, HPA031518" Uncertain Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria, Cytosol" "HPA018447: AB_1853867, HPA031518: AB_2673919" "unprognostic (8.19e-3)" "unprognostic (6.48e-2)" "unprognostic (9.62e-3)" "prognostic favorable (3.78e-4)" "unprognostic (3.30e-1)" "unprognostic (7.02e-2)" "unprognostic (1.15e-1)" "unprognostic (2.53e-2)" "unprognostic (5.83e-2)" "unprognostic (7.38e-3)" "unprognostic (4.44e-1)" "unprognostic (2.81e-1)" "unprognostic (1.54e-3)" "unprognostic (2.19e-1)" "unprognostic (3.39e-1)" "unprognostic (2.12e-1)" "prognostic favorable (8.38e-4)" 8.6 15.3 5.1 6.0 4.9 3.2 9.8 5.3 6.9 12.3 4.7 11.1 8.6 8.0 5.1 7.9 9.3 7.1 8.4 4.8 5.1 11.0 22.0 6.2 11.0 5.6 4.8 12.0 12.5 5.3 7.3 4.5 5.7 10.7 4.5 1.0 18.8 6.2 11.6 7.9 7.3 4.6 5.0 9.0 11.5 4.1 5.4 4.3 8.0 8.1 4.9 10.7 9.0 5.8 13.8 8.5 3.4 5.5 6.3 16.0 6.5 9.9 13.8 14.2 8.8 3.8 4.8 15.1 4.6 5.6 3.4 9.5 6.9 6.3 6.9 14.6 27.2 5.3 5.8 10.7 13.4 9.7 7.7 10.9 13.8 8.0 12.6 7.5 11.0 4.2 8.2 13.1 5.7 20.1 4.3 8.9 8.4 15.0 20.9 8.6 10.8 17.2 15.9 3.9 11.8 10.8 5.4 20.5 25.9 2.9 8.6 5.9 6.0 19.3 10.2 18.6 9.2 18.2 15.9 13.5 13.5 7.1 13.2 10.1 7.8 4.1 6.1 15.2 7.3 13.0 6.2 7.2 11.5 9.6 6.6 8.3 0.4 11.1 12.0 6.0 4.9 5.9 5.1 4.9 5.3 6.9 4.8 5.1 5.6 4.8 5.7 5.0 5.4 5.8 21.4 22.4 19.6 14.4 22.8 11.6 22.2 23.3 40.5 5.5 29.4 37.7 7.8 18.6 23.9 20.2 6.2 16.0 16.7 9.0 29.4 25.0 5.5 12.7 23.3 18.4 19.8 12.6 10.0 28.0 13.5 21.4 11.7 21.6 23.4 17.2 20.3 36.3 27.9 5.0 11.2 14.6 16.2 19.0 14.9 4.3 18.6 19.2 14.2 9.4 22.6 17.4 41.2 16.1 14.2 21.2 11.3 11.7 34.1 20.5 20.2 58.1 24.1 8.1 6.6 19.1 21.9 15.1 16.7 19.8 15.6 13.3 15.9 27.1 21.2 17.2 HSD11B2 SDR9C3 ENSG00000176387 "Hydroxysteroid 11-beta dehydrogenase 2" P80365 16 67430652-67437553 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 249.9;kidney: 335.2;salivary gland: 260.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 191.3;Distal enterocytes: 476.1;Intestinal goblet cells: 288.8;Paneth cells: 226.2;Proximal enterocytes: 270.2;Syncytiotrophoblasts: 114.5;Undifferentiated cells: 170.9" "Cancer enhanced" "Detected in all" "renal cancer: 62.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 11.4;OE19: 29.0;RPMI-8226: 13.9;RT4: 13.9;SCLC-21H: 14.9;SK-BR-3: 13.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB032443, HPA042186, HPA056385" Enhanced Approved "Nucleoplasm,Lipid droplets" NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Lipid droplets" Nucleoplasm "CAB032443: AB_2233199, HPA042186: AB_2677888, HPA056385: AB_2683110" "unprognostic (2.87e-3)" "unprognostic (5.24e-2)" "unprognostic (7.10e-2)" "unprognostic (6.55e-2)" "unprognostic (9.29e-3)" "unprognostic (3.14e-1)" "unprognostic (2.68e-2)" "unprognostic (2.07e-1)" "unprognostic (2.21e-3)" "unprognostic (2.25e-3)" "unprognostic (3.27e-2)" "unprognostic (2.34e-1)" "prognostic favorable (9.51e-5)" "unprognostic (7.20e-2)" "unprognostic (3.19e-1)" "unprognostic (1.55e-2)" "unprognostic (1.84e-1)" 2.1 5.4 1.6 13.4 4.6 0.1 14.0 2.8 2.8 15.5 0.7 249.9 40.0 11.8 4.0 10.9 10.4 6.8 1.9 1.6 1.3 335.2 5.5 3.2 1.0 2.7 1.3 9.3 7.4 3.6 0.5 13.0 3.3 12.9 102.2 0.0 260.2 6.2 0.9 66.1 141.8 18.3 1.5 7.0 9.8 2.5 2.0 0.4 11.1 0.2 0.9 5.3 23.6 2.4 3.6 1.1 0.4 1.4 0.1 1.7 3.6 0.0 0.0 0.1 0.1 6.1 1.3 0.0 2.7 0.1 0.1 7.8 5.1 0.5 0.0 0.0 1.8 0.0 0.7 6.6 0.6 0.7 0.0 1.7 3.0 0.3 0.1 0.0 0.0 4.6 0.4 0.0 0.0 3.8 0.2 0.2 11.4 29.0 1.0 0.0 0.2 13.9 0.5 13.9 14.9 1.0 0.8 13.4 0.6 1.3 6.5 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 4.6 2.8 2.8 1.6 1.3 2.7 1.3 3.3 1.5 2.0 2.4 0.7 0.0 0.5 0.0 1.1 1.5 7.2 1.3 1.2 0.0 4.8 2.2 0.5 30.0 2.3 191.3 0.0 1.2 0.3 476.1 45.0 2.1 0.2 17.4 25.2 0.5 26.9 0.0 1.1 3.0 0.7 7.1 7.1 43.5 8.9 43.4 1.1 1.2 1.4 0.0 0.8 288.8 4.1 0.3 0.5 0.5 25.4 0.7 1.8 0.0 0.0 0.0 0.0 0.5 0.3 0.6 226.2 6.8 0.2 13.5 270.2 16.3 0.4 0.0 13.1 0.3 3.9 0.2 1.6 3.5 3.4 114.5 1.2 16.7 170.9 10.5 HSD17B10 "17b-HSD10, ABAD, CAMR, ERAB, HADH2, MHBD, MRPP2, MRXS10, SDR5C1" ENSG00000072506 "Hydroxysteroid 17-beta dehydrogenase 10" Q99714 X 53431258-53434370 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Steroid metabolism, tRNA processing" Oxidoreductase "Disease variant, FDA approved drug targets, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 444.0;Proximal tubular cells: 427.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001432 Approved NA NA 290000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA001432: AB_1078740" "unprognostic (1.27e-1)" "prognostic favorable (2.80e-4)" "unprognostic (2.60e-1)" "unprognostic (2.15e-1)" "unprognostic (2.10e-1)" "unprognostic (1.30e-1)" "unprognostic (8.37e-2)" "unprognostic (5.24e-2)" "unprognostic (1.02e-1)" "unprognostic (8.64e-3)" "unprognostic (4.08e-3)" "unprognostic (2.04e-1)" "unprognostic (1.95e-2)" "unprognostic (8.38e-2)" "unprognostic (3.07e-3)" "unprognostic (2.92e-1)" "unprognostic (9.51e-2)" 71.1 110.7 63.5 52.5 67.5 64.8 62.7 70.0 64.7 58.1 64.6 62.8 58.0 62.0 56.2 111.6 55.4 33.4 103.8 62.0 68.4 99.1 261.3 48.4 59.4 70.4 68.2 67.1 74.8 73.4 66.1 37.2 67.8 50.7 62.9 12.7 55.0 46.0 90.5 90.0 50.3 62.0 66.6 52.0 66.4 21.5 69.1 60.1 66.4 81.6 76.3 56.3 59.8 69.2 121.9 203.1 97.2 181.3 93.4 41.0 146.5 73.7 72.9 192.0 125.3 210.3 101.8 205.8 65.6 84.9 124.2 124.5 316.1 148.7 104.3 164.1 177.7 97.1 283.6 177.0 156.3 185.1 145.5 87.6 138.9 148.7 82.8 41.6 142.2 181.2 141.6 158.1 90.3 426.7 165.3 277.0 269.9 163.0 259.5 166.2 179.2 364.9 149.3 132.2 171.1 225.1 211.7 250.2 138.6 123.0 263.3 169.8 64.2 81.7 129.7 171.9 113.4 128.3 194.1 256.5 113.4 384.9 123.2 54.2 127.8 40.4 84.8 125.1 87.2 98.8 78.0 84.1 176.7 111.4 64.4 67.9 10.5 98.7 94.5 96.5 114.8 126.6 63.5 67.5 70.0 64.7 62.0 68.4 70.4 68.2 67.8 66.6 69.1 69.2 42.8 48.1 37.3 4.9 61.8 86.4 90.2 150.8 44.9 11.8 72.5 74.9 62.0 107.2 70.2 101.2 4.2 173.2 55.0 73.8 283.7 131.5 1.6 26.1 64.7 58.3 104.6 71.3 2.5 135.4 228.1 72.0 28.1 51.9 56.5 75.3 56.4 444.0 136.8 13.5 3.3 78.2 99.7 73.9 98.6 5.7 78.3 65.4 96.0 3.7 118.7 61.3 89.6 6.6 6.2 101.9 54.1 94.8 83.3 74.6 78.5 427.8 31.5 13.2 78.9 63.1 117.9 23.6 56.3 91.3 116.2 151.6 62.4 104.1 103.0 83.7 HSD17B11 "17-BETA-HSD11, 17-BETA-HSDXI, DHRS8, PAN1B, RetSDR2, SDR16C2" ENSG00000198189 "Hydroxysteroid 17-beta dehydrogenase 11" Q8NBQ5 4 87336515-87391188 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 288.6;liver: 241.6" "Cell type enhanced" "Detected in all" "Paneth cells: 498.6;Proximal enterocytes: 1134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 768.7" "Group enriched" "Detected in all" 4 "granulocytes: 768.7;monocytes: 202.0" "Cell line enhanced" "Detected in many" "CAPAN-2: 295.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021608 Enhanced Supported "Lipid droplets" "Intracellular and membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "Lipid droplets" "HPA021608: AB_1847660" "unprognostic (4.53e-2)" "unprognostic (1.61e-1)" "unprognostic (2.35e-2)" "unprognostic (4.14e-2)" "unprognostic (9.68e-2)" "unprognostic (1.92e-1)" "unprognostic (3.35e-1)" "unprognostic (3.70e-2)" "unprognostic (1.78e-1)" "unprognostic (8.53e-2)" "unprognostic (1.24e-3)" "unprognostic (1.83e-1)" "unprognostic (2.65e-3)" "unprognostic (5.53e-2)" "unprognostic (2.13e-2)" "unprognostic (2.44e-2)" "unprognostic (1.04e-2)" 56.0 64.1 15.0 33.0 15.7 109.9 45.5 19.7 18.6 44.0 18.8 139.6 216.7 57.5 28.2 21.5 44.2 107.7 21.0 15.6 18.4 75.9 241.6 104.4 41.5 20.1 17.5 60.6 54.5 10.9 13.1 47.2 18.9 25.5 145.8 8.2 14.8 34.2 12.1 14.5 288.6 49.4 19.3 42.7 36.6 10.1 16.7 36.3 19.3 26.3 34.9 41.8 33.5 22.8 1.0 45.4 22.2 56.1 66.5 92.4 31.2 23.4 39.3 16.1 29.9 38.2 295.2 0.0 45.8 26.2 14.8 0.9 65.6 5.2 18.0 72.1 13.8 63.3 22.9 131.0 37.6 114.8 114.0 65.3 1.7 22.5 7.4 51.3 31.5 27.4 67.9 32.7 30.1 1.8 24.0 144.8 37.8 146.7 7.6 63.2 20.4 77.7 45.5 70.0 7.2 69.3 47.5 1.6 87.0 28.2 0.1 112.7 24.9 11.0 47.9 43.1 13.0 15.0 6.6 7.1 20.1 80.6 77.0 591.1 202.0 442.9 62.5 142.7 74.8 57.1 62.6 64.6 108.2 47.6 55.8 64.2 768.7 82.3 125.8 36.8 77.4 171.6 15.0 15.7 19.7 18.6 15.6 18.4 20.1 17.5 18.9 19.3 16.7 22.8 169.0 314.1 179.5 13.4 89.0 28.0 77.0 16.0 10.8 1.8 5.0 6.2 5.3 368.9 83.7 44.1 2.1 30.6 63.1 356.8 25.4 53.9 1.2 9.0 28.1 101.8 93.7 68.8 16.8 58.6 59.7 77.3 28.1 18.8 100.1 34.1 112.5 337.3 129.1 18.5 14.7 180.8 18.3 220.4 176.2 5.1 104.1 139.1 67.6 43.1 197.3 36.3 113.3 16.6 19.0 65.9 498.6 59.5 60.8 39.5 1134.9 173.6 62.2 3.9 72.3 77.9 43.0 2.7 15.4 10.4 21.5 14.9 93.8 65.4 281.0 93.9 HSD17B12 "KAR, SDR12C1" ENSG00000149084 "Hydroxysteroid 17-beta dehydrogenase 12" Q53GQ0 11 43680680-43856617 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016427 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "HPA016427: AB_1844347" "unprognostic (1.93e-1)" "unprognostic (1.92e-2)" "unprognostic (1.53e-1)" "unprognostic (1.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.14e-3)" "prognostic unfavorable (2.76e-4)" "unprognostic (2.99e-1)" "unprognostic (3.31e-2)" "unprognostic (9.16e-3)" "unprognostic (5.16e-2)" "unprognostic (7.54e-2)" "prognostic favorable (2.10e-8)" "unprognostic (6.87e-2)" "unprognostic (1.49e-1)" "unprognostic (2.43e-1)" "unprognostic (2.28e-2)" 60.9 65.4 42.0 31.4 50.4 25.1 48.8 58.1 63.0 51.3 71.5 65.8 67.3 37.4 50.6 36.3 41.3 35.6 69.5 42.0 54.3 91.3 122.9 51.4 28.5 58.8 52.1 45.3 43.5 134.3 28.5 41.6 58.9 52.8 59.5 47.0 46.9 41.5 27.8 30.0 41.7 48.6 52.8 34.8 56.1 33.5 48.9 22.3 66.8 51.6 32.3 31.4 26.8 61.9 40.2 64.3 68.4 69.6 226.8 211.5 45.0 96.7 97.8 67.3 73.0 75.7 80.7 97.4 69.4 91.5 111.7 151.6 48.7 125.5 82.6 19.0 89.2 46.4 28.3 66.2 114.6 132.3 125.4 131.1 93.6 68.1 193.6 85.9 96.1 60.4 43.9 157.9 59.4 22.9 38.6 63.1 126.0 49.9 45.3 63.9 102.3 110.8 129.5 95.9 24.5 56.5 132.0 110.7 100.2 64.6 80.2 112.5 92.4 73.9 28.3 189.3 117.6 81.6 110.3 58.3 78.5 25.0 55.4 8.8 13.4 7.0 12.1 14.8 13.5 12.7 9.6 10.5 21.3 15.2 15.6 13.9 11.2 16.4 8.2 18.4 6.2 11.6 42.0 50.4 58.1 63.0 42.0 54.3 58.8 52.1 58.9 52.8 48.9 61.9 73.6 64.1 111.1 96.6 45.4 31.7 47.1 92.8 57.5 77.1 46.1 36.4 80.7 74.4 81.4 51.5 77.2 60.4 30.6 82.2 27.4 100.2 61.8 36.9 47.5 70.9 138.2 40.8 126.9 82.3 42.1 59.7 60.6 37.0 155.9 37.3 76.1 214.0 63.5 121.1 155.6 75.5 87.5 50.9 43.7 24.1 34.2 45.3 39.2 59.0 37.2 128.2 30.9 128.7 97.5 71.4 62.5 56.8 61.4 61.3 54.2 50.1 75.8 67.8 78.9 45.4 60.2 17.5 14.5 66.0 45.7 74.8 29.4 95.5 115.5 48.6 HSD17B14 "DHRS10, retSDR3, SDR47C1" ENSG00000087076 "Hydroxysteroid 17-beta dehydrogenase 14" Q9BPX1 19 48813018-48836510 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 78.2;Hofbauer cells: 149.9;Proximal tubular cells: 434.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "B-cells: 3.7;NK-cells: 4.7;T-cells: 3.1" "Cell line enhanced" "Detected in many" "GAMG: 53.9;HHSteC: 49.5;hTERT-RPE1: 37.9;Karpas-707: 50.7;RT4: 40.5" "Not detected" "Not detected" HPA021467 Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA021467: AB_1847652" "unprognostic (2.03e-1)" "unprognostic (7.94e-3)" "prognostic unfavorable (4.39e-5)" "unprognostic (4.32e-2)" "unprognostic (8.03e-2)" "unprognostic (1.47e-1)" "unprognostic (7.54e-2)" "unprognostic (7.76e-3)" "unprognostic (2.71e-1)" "unprognostic (4.04e-1)" "prognostic favorable (2.87e-5)" "unprognostic (4.56e-1)" "unprognostic (5.50e-3)" "unprognostic (9.05e-3)" "unprognostic (1.01e-1)" "unprognostic (5.51e-2)" "unprognostic (1.81e-2)" 9.2 39.5 38.1 3.2 36.3 1.2 11.2 42.8 47.7 34.1 72.5 10.5 3.3 31.6 5.6 4.2 22.7 11.6 8.1 37.2 38.2 58.2 78.8 13.1 8.0 35.6 41.2 56.2 6.2 46.7 24.1 7.3 35.3 15.0 1.9 10.0 6.4 9.2 1.3 7.7 8.2 8.5 35.8 8.7 8.6 4.8 43.6 9.6 25.3 2.2 3.8 15.8 14.6 37.0 0.1 14.0 14.1 2.4 15.8 2.6 0.3 2.6 19.9 1.1 1.2 13.4 0.2 8.0 14.2 0.6 53.9 0.1 1.3 0.1 1.3 0.5 1.0 4.1 0.3 1.8 49.5 0.0 20.9 19.0 0.5 1.2 0.5 37.9 18.1 4.8 0.1 50.7 0.1 0.5 1.1 0.4 1.2 8.2 9.3 7.9 0.1 1.5 0.0 40.5 3.5 9.0 0.0 1.8 10.9 6.0 0.4 0.5 0.0 0.3 5.2 0.5 0.1 8.9 18.9 0.6 11.9 1.2 0.1 0.0 0.0 0.0 0.9 0.0 1.5 3.7 1.5 0.7 0.0 2.5 3.1 2.3 0.0 4.7 0.0 0.5 0.5 0.8 38.1 36.3 42.8 47.7 37.2 38.2 35.6 41.2 35.3 35.8 43.6 37.0 3.3 3.2 11.5 21.5 6.0 2.5 3.6 1.7 0.0 5.5 1.3 5.0 2.0 1.5 4.4 7.3 0.0 1.4 0.3 0.0 78.2 1.9 0.4 0.3 3.5 8.2 13.2 5.3 5.0 1.1 3.0 14.1 2.0 0.7 7.0 7.4 28.5 32.0 149.9 11.8 5.0 0.3 8.2 13.4 9.5 1.4 4.1 17.3 21.4 6.5 8.0 53.5 1.0 4.5 0.8 2.6 0.0 7.2 0.1 3.8 2.2 434.5 0.7 1.6 0.0 2.4 2.9 5.6 15.7 0.3 1.8 2.2 2.8 7.5 0.2 2.9 HSD17B6 "HSE, RODH, SDR9C6" ENSG00000025423 "Hydroxysteroid 17-beta dehydrogenase 6" O14756 12 56752161-56787790 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "liver: 1804.3" "Cell type enriched" "Detected in many" 11 "Hepatocytes: 1969.3" "Cancer enriched" "Detected in many" 5 "liver cancer: 170.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Karpas-707: 13.4;U-266/84: 18.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059141 Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 16: U-266 - Nucleosome" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Vesicles" "HPA059141: AB_2683922" "unprognostic (7.70e-2)" "unprognostic (8.76e-2)" "unprognostic (5.08e-2)" "unprognostic (1.92e-2)" "unprognostic (2.01e-1)" "unprognostic (3.79e-2)" "prognostic favorable (6.32e-4)" "unprognostic (1.06e-2)" "unprognostic (3.21e-1)" "unprognostic (1.44e-1)" "unprognostic (1.35e-1)" "unprognostic (6.74e-2)" "unprognostic (2.50e-10)" "unprognostic (1.26e-1)" "unprognostic (1.79e-1)" "unprognostic (1.08e-1)" "unprognostic (1.05e-1)" 8.5 2.5 13.1 6.9 16.2 0.5 0.7 13.4 18.9 28.0 9.4 24.7 3.2 20.9 1.6 9.9 6.5 9.1 0.8 12.3 12.6 2.5 1804.3 63.2 0.8 12.0 14.6 6.0 0.6 0.5 0.6 5.4 11.5 51.2 7.6 0.8 0.4 69.2 0.4 1.2 4.8 13.1 12.4 47.5 5.7 23.3 13.7 0.9 31.4 0.5 0.9 36.7 14.6 12.8 0.3 0.8 1.9 0.4 1.9 1.4 2.3 4.1 3.5 1.9 1.9 0.4 0.4 12.0 1.7 0.5 0.5 0.3 6.1 1.1 1.1 7.7 2.2 3.7 1.2 0.6 1.2 1.9 6.0 1.0 0.4 1.2 0.6 0.6 0.0 10.3 1.1 13.4 0.9 2.4 5.6 1.3 7.5 0.7 0.7 7.4 0.8 2.9 0.2 1.4 11.0 2.3 2.0 3.6 0.9 0.7 0.6 1.5 0.3 0.9 0.8 4.0 1.0 11.7 18.0 7.8 1.3 6.9 0.6 0.0 0.0 0.0 1.0 0.2 1.2 0.7 0.8 0.8 0.2 0.3 1.1 0.7 0.0 0.0 0.5 0.7 1.0 0.3 13.1 16.2 13.4 18.9 12.3 12.6 12.0 14.6 11.5 12.4 13.7 12.8 0.4 173.1 130.6 21.2 6.1 1.3 3.1 0.6 0.6 0.4 0.7 0.6 0.2 27.1 9.3 0.0 0.0 1.4 0.4 0.0 0.0 0.1 4.6 0.7 3.5 1.3 0.0 29.5 1.4 0.0 2.6 5.0 0.0 0.1 0.0 1.6 26.0 1969.3 0.4 0.0 2.1 0.4 0.0 40.2 0.3 4.5 12.5 0.5 0.0 1.0 1.0 1.3 0.0 3.0 5.5 0.1 0.0 1.5 0.8 16.1 0.0 0.3 1.5 0.6 13.1 0.6 3.5 16.4 11.4 1.2 1.6 0.4 2.2 36.0 0.7 1.1 HSPB2 "Hs.78846, MKBP" ENSG00000170276 "Heat shock protein family B (small) member 2" Q16082 11 111912734-111914093 "Predicted intracellular proteins" "Stress response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 153.2;skeletal muscle: 251.3;tongue: 316.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 115.7;Fibroblasts: 39.1;Leydig cells: 43.5;Melanocytes: 37.4;Smooth muscle cells: 39.8" "Cancer enhanced" "Detected in many" "melanoma: 5.1;renal cancer: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 48.4;ASC TERT1: 23.4;fHDF/TERT166: 59.7;HSkMC: 23.3;LHCN-M2: 35.2;U-138 MG: 31.5" HPA079414 Approved NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA079414: " "unprognostic (5.46e-2)" "unprognostic (1.46e-1)" "unprognostic (2.30e-1)" "unprognostic (7.69e-3)" "unprognostic (6.82e-2)" "unprognostic (1.51e-2)" "unprognostic (4.37e-2)" "unprognostic (3.25e-1)" "unprognostic (2.04e-1)" "unprognostic (1.67e-2)" "unprognostic (3.55e-2)" "unprognostic (2.19e-1)" "unprognostic (1.36e-1)" "unprognostic (1.69e-3)" "unprognostic (2.63e-1)" "unprognostic (1.99e-1)" "unprognostic (1.46e-2)" 39.8 5.3 26.7 4.3 28.9 0.0 21.5 37.4 32.5 30.2 24.4 21.1 3.4 25.0 5.7 15.4 22.2 18.5 153.2 25.8 26.7 13.3 2.3 17.3 5.4 29.0 27.3 14.0 1.4 1.4 3.8 12.2 27.2 13.1 4.0 1.8 7.1 13.0 251.3 14.7 9.1 19.1 27.2 7.3 9.6 2.3 28.9 1.4 9.6 316.8 2.0 16.1 19.0 26.2 0.0 0.0 0.0 7.0 48.4 23.4 0.2 5.6 0.0 0.0 0.3 0.0 0.0 0.0 0.5 59.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.0 0.0 0.0 23.3 0.0 0.0 0.0 4.2 0.0 0.0 0.2 0.0 35.2 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.2 31.5 3.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.7 28.9 37.4 32.5 25.8 26.7 29.0 27.3 27.2 27.2 28.9 26.2 8.5 0.0 0.0 0.0 0.0 7.0 0.3 0.0 1.2 0.4 5.1 16.4 115.7 1.5 0.6 1.8 0.0 0.8 0.1 0.0 1.9 0.4 0.1 0.1 7.9 3.5 0.0 0.0 0.0 0.0 0.7 39.1 0.0 0.2 0.0 0.4 4.6 0.0 1.4 0.0 0.0 0.0 0.0 0.0 10.3 1.1 43.5 0.6 37.4 0.0 0.0 7.6 0.0 0.0 0.0 0.1 0.0 21.8 0.0 0.3 0.0 23.5 0.0 0.5 13.1 22.8 39.8 0.8 0.6 0.6 5.8 1.5 1.0 0.4 0.0 0.0 HSPG2 "perlecan, PRCAN, SJS1" ENSG00000142798 "Heparan sulfate proteoglycan 2" P98160 1 21822244-21937310 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 366.8;Endothelial cells: 322.9;Granulosa cells: 776.0;Hepatic stellate cells: 600.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 293.0;HUVEC TERT2: 620.8;TIME: 504.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009820, HPA018892, CAB020718, HPA072690" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 1400000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "CAB009820: AB_2119229, CAB020718: , HPA018892: AB_1850597, HPA072690: " "unprognostic (1.61e-1)" "unprognostic (1.57e-2)" "unprognostic (4.93e-2)" "unprognostic (9.60e-2)" "unprognostic (2.38e-2)" "unprognostic (8.56e-2)" "unprognostic (4.55e-1)" "unprognostic (1.90e-2)" "unprognostic (9.35e-2)" "unprognostic (2.19e-3)" "unprognostic (5.82e-2)" "unprognostic (2.83e-1)" "unprognostic (1.21e-3)" "unprognostic (1.17e-2)" "unprognostic (4.86e-2)" "unprognostic (1.46e-2)" "prognostic unfavorable (2.82e-4)" 140.7 54.7 3.8 36.1 5.2 1.7 96.2 3.7 4.8 65.9 18.8 153.1 18.3 151.9 6.6 44.1 85.0 53.4 156.6 3.6 2.9 37.6 10.6 49.0 14.2 5.6 4.6 31.3 31.7 13.1 11.8 30.3 5.7 60.3 8.6 0.3 45.0 56.5 65.1 41.0 54.9 96.2 4.0 37.4 76.1 9.0 7.6 6.7 69.1 40.8 3.5 110.2 59.7 4.7 44.0 40.7 13.8 45.9 131.0 99.4 51.5 70.2 17.8 21.1 18.7 50.5 86.7 3.3 293.0 112.9 0.8 26.9 3.1 31.9 5.4 0.6 4.3 15.7 46.0 35.7 27.0 0.0 4.1 61.6 9.4 19.9 6.0 28.1 620.8 0.3 21.4 5.7 32.4 11.8 0.0 20.0 11.7 19.6 17.9 6.3 87.8 6.1 35.1 6.5 1.3 4.1 51.4 20.0 28.7 14.0 8.1 7.2 504.3 41.1 51.8 29.7 2.3 0.5 7.3 2.6 9.7 0.1 54.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 3.8 5.2 3.7 4.8 3.6 2.9 5.6 4.6 5.7 4.0 7.6 4.7 366.8 70.5 28.6 3.6 3.9 26.4 13.5 81.1 21.1 0.6 6.2 21.5 5.8 38.6 30.3 92.0 0.0 11.0 3.4 52.9 0.0 76.1 1.4 24.2 47.7 322.9 2.4 22.9 0.8 25.0 89.0 141.3 62.2 39.8 23.4 776.0 600.4 6.6 6.8 3.3 0.8 12.6 16.2 22.1 19.2 5.8 75.2 4.6 60.5 15.9 1.8 1.6 0.0 2.5 4.3 87.5 29.9 69.2 4.6 19.3 19.2 0.9 28.7 0.6 32.9 82.5 69.8 0.3 4.8 10.0 17.8 9.3 5.0 83.3 20.1 11.8 HYAL1 "HYAL-1, LUCA1" ENSG00000114378 "Hyaluronidase 1" Q12794 3 50299890-50312381 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 201.6;lymphoid tissue: 95.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 30.0;Hepatic stellate cells: 33.2;Hepatocytes: 137.1;Proximal tubular cells: 58.2" "Cancer enhanced" "Detected in all" "liver cancer: 37.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.1" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "Hep G2: 100.9;SK-BR-3: 28.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002112 Uncertain "Secreted to blood" NA NA 590000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA002112: AB_1857412" "unprognostic (1.39e-1)" "unprognostic (8.68e-2)" "prognostic favorable (2.07e-4)" "unprognostic (5.23e-2)" "unprognostic (3.18e-1)" "unprognostic (8.71e-2)" "unprognostic (9.35e-2)" "unprognostic (3.59e-2)" "unprognostic (6.56e-2)" "unprognostic (1.31e-1)" "unprognostic (6.65e-3)" "unprognostic (1.16e-1)" "prognostic favorable (1.56e-11)" "unprognostic (4.51e-2)" "unprognostic (5.89e-2)" "unprognostic (1.95e-1)" "unprognostic (1.90e-2)" 11.4 21.5 5.0 2.8 4.5 0.3 9.2 6.4 6.3 10.8 18.3 6.8 3.4 8.2 0.8 5.5 7.3 13.2 68.2 4.5 4.0 49.4 201.6 30.7 1.8 5.4 4.8 3.0 9.4 19.9 3.3 2.4 5.6 4.6 2.9 3.1 7.3 2.9 15.0 21.1 6.0 5.9 3.5 95.1 19.4 1.7 5.8 0.8 8.3 19.0 1.2 4.8 12.3 4.7 2.9 1.8 0.4 0.9 0.6 0.7 0.5 0.1 0.3 0.1 0.4 11.4 3.1 0.0 0.8 0.6 0.6 6.6 0.2 0.4 0.0 0.1 0.0 0.3 8.6 100.9 4.4 0.7 0.7 3.9 13.8 0.1 0.4 0.8 2.9 0.3 0.3 0.5 0.4 0.6 0.1 0.3 0.6 7.1 0.6 0.0 0.2 0.3 5.9 0.4 0.2 2.1 0.2 28.0 0.3 2.4 2.0 0.3 1.9 0.6 0.6 0.6 0.3 0.2 0.3 0.4 0.4 0.6 0.3 1.3 0.4 1.5 0.3 0.1 0.8 0.4 0.3 0.4 0.2 0.5 0.6 0.4 3.1 0.3 0.3 0.5 0.4 0.1 5.0 4.5 6.4 6.3 4.5 4.0 5.4 4.8 5.6 3.5 5.8 4.7 18.1 19.2 18.5 1.6 0.3 2.9 0.4 3.3 0.0 1.0 0.3 0.1 20.8 30.0 2.0 11.0 4.2 0.1 0.0 2.5 23.5 16.5 8.2 0.2 0.9 25.8 1.8 2.7 3.1 14.4 0.1 3.3 19.4 0.2 0.0 0.6 33.2 137.1 0.1 0.0 3.1 1.4 0.0 4.4 0.9 7.7 2.1 0.9 0.0 7.5 0.0 0.4 0.0 1.5 1.6 12.1 0.3 1.2 0.0 0.2 0.4 58.2 0.9 0.5 6.6 1.2 4.3 0.4 1.1 0.9 3.1 0.7 0.9 7.4 0.9 1.7 HYAL2 "LuCa-2, LUCA2" ENSG00000068001 "Hyaluronidase 2" Q12891 3 50317790-50322782 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 282.8" "Group enriched" "Detected in many" 5 "Adipocytes: 497.6;Endothelial cells: 216.3;Hepatic stellate cells: 253.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 4 "HUVEC TERT2: 363.3;TIME: 502.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036436 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA036436: AB_10670104" "unprognostic (9.97e-3)" "unprognostic (2.60e-1)" "unprognostic (1.44e-1)" "unprognostic (5.10e-3)" "unprognostic (3.44e-1)" "unprognostic (7.41e-2)" "unprognostic (7.93e-2)" "unprognostic (4.70e-1)" "unprognostic (1.44e-1)" "unprognostic (6.76e-2)" "unprognostic (2.36e-1)" "unprognostic (3.01e-1)" "unprognostic (2.63e-3)" "unprognostic (7.36e-2)" "unprognostic (2.72e-1)" "unprognostic (7.02e-3)" "unprognostic (5.62e-2)" 97.4 62.6 24.7 29.1 23.0 3.1 93.9 24.9 28.3 51.6 24.3 34.0 17.9 66.1 10.3 39.7 55.6 47.5 92.2 22.3 24.8 85.1 32.2 186.8 40.0 26.0 24.9 29.1 27.9 25.7 41.6 87.4 27.5 37.2 11.5 3.3 37.5 22.0 30.9 37.1 38.7 37.4 27.1 282.8 38.6 22.0 28.1 9.5 80.9 35.7 14.6 47.0 45.8 24.9 26.8 38.5 63.0 64.1 38.2 32.9 39.6 29.8 41.2 42.0 32.6 44.6 77.3 7.0 102.4 43.6 82.5 27.4 24.6 58.7 12.0 14.2 19.6 9.7 34.9 69.2 33.0 8.1 24.4 51.9 48.8 42.1 13.8 38.1 363.3 18.2 17.6 8.0 35.4 37.0 17.7 16.6 72.0 23.2 55.7 15.5 12.4 26.1 52.4 24.2 16.6 53.3 30.4 31.2 31.8 21.2 34.4 20.3 502.9 50.0 49.7 33.5 47.5 13.9 24.1 21.6 29.4 25.5 73.0 0.0 9.5 10.7 1.4 14.1 3.0 1.1 1.3 3.8 5.3 1.5 0.4 0.7 9.2 2.8 13.6 4.0 1.9 3.3 24.7 23.0 24.9 28.3 22.3 24.8 26.0 24.9 27.5 27.1 28.1 24.9 497.6 19.2 9.9 5.2 3.6 13.0 28.6 45.2 11.4 7.8 17.6 16.6 7.3 32.9 30.9 33.1 6.2 33.6 4.1 13.5 11.7 53.0 4.7 8.5 19.8 216.3 7.3 10.1 1.6 38.7 38.4 26.6 16.8 13.8 0.0 31.5 253.1 9.1 46.2 8.4 1.9 13.0 42.7 12.6 9.3 5.0 24.5 9.4 17.8 15.9 7.6 19.7 5.2 4.0 3.4 45.6 13.5 22.2 4.2 45.3 16.1 11.8 11.0 6.1 39.5 11.2 26.0 11.2 56.0 24.9 12.6 32.7 4.1 50.0 16.6 33.3 IARS2 FLJ10326 ENSG00000067704 "Isoleucyl-tRNA synthetase 2, mitochondrial" Q9NSE4 1 220094132-220148041 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Cataract, Deafness, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024212, HPA024594, HPA024596" Enhanced Enhanced Mitochondria NA NA 35000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA024212: AB_1851363, HPA024594: AB_1851368, HPA024596: AB_1851370" "unprognostic (2.15e-2)" "prognostic unfavorable (1.04e-4)" "unprognostic (2.42e-3)" "unprognostic (3.22e-2)" "unprognostic (2.04e-1)" "unprognostic (1.55e-1)" "unprognostic (1.91e-1)" "unprognostic (7.81e-2)" "unprognostic (1.78e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (9.24e-5)" "unprognostic (9.48e-2)" "unprognostic (2.10e-2)" "unprognostic (3.01e-1)" "unprognostic (2.16e-1)" "unprognostic (8.87e-2)" "unprognostic (6.27e-3)" 55.8 49.8 19.9 33.3 21.1 18.3 41.8 23.5 25.4 35.3 37.8 54.2 43.4 31.8 31.4 47.9 41.4 30.5 60.0 20.0 21.8 65.5 83.8 31.0 38.8 22.7 22.2 39.0 33.6 80.5 16.0 40.7 25.0 36.1 54.8 34.8 40.0 37.5 92.9 40.5 40.4 39.4 21.6 28.4 39.1 30.1 22.3 31.8 39.7 85.7 43.1 35.6 30.0 22.9 137.2 125.6 70.7 69.9 104.2 104.4 169.6 81.4 86.9 87.9 70.7 121.7 138.8 125.6 107.1 101.4 68.0 129.3 99.0 101.5 100.9 87.5 119.3 62.6 94.6 137.8 64.6 100.4 64.9 76.0 101.3 95.4 97.6 84.7 86.9 79.9 156.9 70.7 116.7 75.9 79.8 72.0 92.1 106.2 82.1 69.5 140.7 202.2 126.2 90.4 38.0 106.6 123.2 188.2 130.3 80.6 218.5 111.9 89.8 86.1 71.6 117.0 138.4 60.0 98.9 90.8 91.3 77.3 97.6 33.8 24.6 22.8 23.0 27.7 30.8 23.6 24.9 30.3 29.2 18.3 27.8 25.6 4.7 28.3 22.3 10.6 29.9 26.7 19.9 21.1 23.5 25.4 20.0 21.8 22.7 22.2 25.0 21.6 22.3 22.9 66.4 35.3 38.0 15.7 30.7 20.1 28.6 44.1 34.7 28.6 40.1 39.4 144.3 22.8 42.9 29.5 25.0 79.0 31.5 54.2 11.7 47.7 20.0 63.8 48.3 43.7 36.2 29.6 17.3 65.4 55.5 37.0 32.1 44.3 19.6 41.3 37.5 99.6 45.9 20.2 22.7 55.4 28.5 51.0 11.2 6.8 37.3 35.9 19.6 15.0 46.1 34.6 27.8 16.6 31.5 67.4 44.9 42.5 33.1 34.1 38.4 36.1 62.0 35.5 46.0 46.3 39.0 44.6 44.1 63.5 26.6 71.7 31.0 54.4 69.9 27.6 ICOS "AILIM, CD278" ENSG00000163600 "Inducible T cell costimulator" Q9Y6W8 2 203936763-203961577 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 16.5;lymphoid tissue: 20.2" "Cell type enriched" "Detected in some" 12 "T-cells: 81.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 29.1" "Lineage enriched" "Detected in single" 54 "T-cells: 29.1" "Group enriched" "Detected in some" 8 "HEL: 4.6;MOLT-4: 12.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB032575, HPA034865" Approved Approved "Plasma membrane,Actin filaments" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Actin filaments" "CAB032575: AB_2122593, HPA034865: " "unprognostic (2.66e-2)" "unprognostic (2.13e-3)" "unprognostic (4.19e-4)" "unprognostic (2.35e-5)" "unprognostic (1.07e-1)" "prognostic favorable (1.80e-4)" "unprognostic (9.38e-2)" "unprognostic (2.89e-2)" "unprognostic (1.49e-2)" "unprognostic (3.51e-4)" "unprognostic (7.50e-2)" "unprognostic (2.12e-1)" "unprognostic (2.86e-5)" "unprognostic (7.05e-2)" "unprognostic (2.48e-2)" "unprognostic (1.93e-1)" "unprognostic (8.82e-3)" 0.5 0.1 0.0 7.7 0.0 16.5 0.3 0.0 0.0 0.2 0.0 0.7 0.7 0.2 0.1 0.5 0.3 1.4 0.2 0.0 0.0 0.2 0.4 2.6 14.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 1.3 0.0 0.4 0.0 0.0 0.2 2.3 0.4 0.0 3.3 1.3 0.2 0.0 20.2 0.4 0.0 16.2 2.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 4.2 0.0 15.1 6.8 0.0 0.0 15.7 7.2 0.1 0.5 0.0 0.0 29.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.3 0.0 3.1 2.9 0.0 0.0 0.0 0.0 1.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 1.1 2.0 0.2 6.3 0.0 0.4 0.1 0.1 0.0 0.0 0.2 0.0 0.8 4.7 0.1 0.0 3.1 3.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.3 0.0 1.8 0.1 81.2 0.0 0.0 0.1 IDH1 ENSG00000138413 "Isocitrate dehydrogenase (NADP(+)) 1" O75874 2 208236229-208266074 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 536.3" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 320.2;Granulosa cells: 257.5;Hepatocytes: 328.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 768.1;RT4: 524.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033218, HPA035248, HPA057936, CAB062556" Enhanced Approved "Nuclear bodies,Cytosol" NA NA 16000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" "Nuclear bodies, Cytosol" "CAB033218: AB_2123166, CAB062556: AB_2665593, HPA035248: AB_10600714, HPA057936: AB_2683559" "unprognostic (2.79e-1)" "unprognostic (1.00e-1)" "unprognostic (1.02e-1)" "unprognostic (2.47e-3)" "unprognostic (1.93e-1)" "unprognostic (2.39e-2)" "prognostic unfavorable (6.93e-5)" "unprognostic (3.32e-1)" "unprognostic (2.20e-3)" "unprognostic (8.03e-2)" "unprognostic (5.54e-2)" "unprognostic (4.18e-3)" "prognostic unfavorable (2.45e-5)" "unprognostic (2.09e-1)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (2.69e-2)" 150.8 230.8 24.0 37.5 23.9 10.7 63.0 24.6 30.9 67.9 40.8 124.9 179.4 22.9 164.9 92.2 36.6 69.5 25.3 23.5 26.1 122.0 536.3 49.8 33.3 26.4 25.7 84.4 39.9 42.0 16.7 82.5 25.9 214.6 131.2 35.0 59.3 79.1 25.7 23.6 117.4 43.8 25.5 40.1 113.6 57.0 30.0 21.8 45.5 28.1 29.8 153.1 39.9 30.6 66.5 109.6 152.5 63.3 275.1 191.4 86.7 26.3 122.3 44.2 107.3 176.1 159.1 13.1 168.8 84.4 181.6 101.4 112.4 130.7 43.0 8.8 41.7 56.7 87.3 768.1 367.3 37.0 54.7 169.5 278.0 102.7 74.2 69.8 126.1 37.2 58.1 44.5 68.9 42.8 26.3 66.2 284.5 479.7 43.9 25.2 54.8 37.8 206.3 524.0 25.9 45.2 100.5 99.7 351.7 161.2 37.9 111.0 81.1 45.2 44.1 65.3 29.6 20.8 34.5 16.9 148.2 226.7 37.0 12.4 70.1 11.0 9.1 32.3 10.6 10.6 8.2 10.9 50.9 10.1 6.7 7.8 13.8 17.2 15.5 18.8 15.1 29.9 24.0 23.9 24.6 30.9 23.5 26.1 26.4 25.7 25.9 25.5 30.0 30.6 13.9 12.8 49.5 39.2 20.2 12.4 18.8 60.5 52.3 19.5 61.8 31.5 21.8 45.8 69.1 29.5 25.0 320.2 23.7 106.8 21.5 31.1 13.8 31.0 23.4 22.0 58.4 30.3 16.6 86.5 178.8 29.6 76.0 108.8 14.0 257.5 39.7 328.2 175.3 11.8 16.2 98.4 57.0 130.2 23.8 11.2 24.5 71.7 26.6 19.7 47.8 25.4 18.6 66.4 20.0 44.8 55.5 29.3 13.7 53.2 181.2 108.5 21.9 56.6 13.1 7.8 23.6 8.0 26.2 82.4 14.9 95.6 19.8 127.1 129.3 46.7 IFIT2 "cig42, G10P2, GARG-39, IFI-54, IFI54, ISG-54K" ENSG00000119922 "Interferon induced protein with tetratricopeptide repeats 2" P09913 10 89283694-89309271 "Predicted intracellular proteins" "Antiviral defense, Apoptosis, Immunity, Innate immunity" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 48.4" "Cell type enhanced" "Detected in many" "Adipocytes: 53.5;Glandular and luminal cells: 67.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 420.2" "Lineage enriched" "Detected in all" 5 "granulocytes: 420.2" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 141.0;BJ hTERT+ SV40 Large T+ RasG12V: 113.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003408 Approved Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA003408: AB_1079100" "unprognostic (1.77e-1)" "unprognostic (2.10e-1)" "unprognostic (2.42e-2)" "unprognostic (2.25e-3)" "unprognostic (1.75e-2)" "unprognostic (9.28e-2)" "unprognostic (6.71e-3)" "unprognostic (2.22e-1)" "unprognostic (5.40e-1)" "unprognostic (1.36e-1)" "unprognostic (7.03e-3)" "unprognostic (1.27e-1)" "prognostic unfavorable (6.99e-4)" "unprognostic (2.92e-2)" "unprognostic (1.03e-2)" "unprognostic (5.33e-3)" "unprognostic (6.46e-2)" 7.7 6.7 12.6 13.1 17.3 48.4 5.4 14.7 16.2 6.1 8.2 5.4 6.7 5.0 6.2 2.8 9.3 13.6 7.5 11.7 14.1 10.2 21.8 21.0 7.9 19.5 16.6 9.2 3.1 10.0 2.5 16.4 18.9 4.1 4.5 1.7 8.8 6.5 2.3 3.7 5.7 6.5 30.1 27.5 3.6 2.2 15.9 12.6 3.4 6.8 5.7 6.3 2.9 20.8 29.3 1.1 0.3 14.5 13.0 14.4 5.2 10.7 32.4 141.0 113.0 0.1 20.0 3.2 5.9 7.8 20.6 28.9 0.6 1.5 15.4 11.6 0.1 5.3 14.3 0.0 22.2 0.7 2.3 8.2 0.7 10.7 1.6 8.6 0.7 2.8 0.1 0.5 2.2 0.1 3.4 6.6 3.5 0.0 6.1 2.1 3.7 0.8 4.8 5.6 0.1 0.2 3.8 0.6 24.7 1.8 0.7 1.6 0.9 1.5 0.3 3.9 1.1 1.4 5.1 0.5 2.3 2.4 2.9 97.6 32.6 107.8 9.5 75.9 5.1 19.2 8.0 6.5 10.6 17.7 7.6 6.8 420.2 8.9 92.3 12.7 3.9 17.6 12.6 17.3 14.7 16.2 11.7 14.1 19.5 16.6 18.9 30.1 15.9 20.8 53.5 41.7 6.7 1.6 12.3 1.5 5.3 6.6 1.2 1.3 5.6 9.5 7.4 11.5 9.4 12.9 0.0 2.9 27.6 23.5 9.8 35.0 0.2 34.9 9.1 34.9 3.5 0.8 1.0 4.2 1.6 10.9 2.0 67.0 5.1 3.8 16.4 6.1 26.0 25.2 2.1 5.9 4.1 25.5 3.3 0.2 8.1 29.5 7.2 4.7 20.9 13.3 12.3 2.0 20.3 6.3 11.5 11.7 2.4 19.1 18.9 30.8 4.7 0.9 0.0 8.3 14.3 0.2 0.2 3.2 0.6 1.4 13.1 6.2 2.1 5.8 IGF1R "CD221, IGFIR, IGFR, JTK13, MGC18216" ENSG00000140443 "Insulin like growth factor 1 receptor" P08069 15 98648539-98964530 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 239.4;Inhibitory neurons: 194.6;Microglial cells: 245.4;Oligodendrocyte precursor cells: 237.7;Oligodendrocytes: 261.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.3" "Group enriched" "Detected in many" 6 "granulocytes: 4.3;T-cells: 1.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010268, HPA045563" Approved NA NA 46000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" "CAB010268: AB_671792, HPA045563: AB_2679368" "unprognostic (1.30e-3)" "unprognostic (5.81e-3)" "unprognostic (1.53e-1)" "unprognostic (3.34e-2)" "unprognostic (2.65e-1)" "unprognostic (2.05e-2)" "unprognostic (1.29e-2)" "unprognostic (6.87e-2)" "unprognostic (2.64e-2)" "unprognostic (2.87e-2)" "unprognostic (8.56e-2)" "unprognostic (1.62e-1)" "prognostic favorable (3.75e-7)" "unprognostic (1.57e-1)" "unprognostic (3.59e-1)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" 7.3 11.3 10.1 3.6 11.2 11.0 12.2 12.0 12.0 10.1 35.5 12.5 2.5 11.0 11.1 7.5 13.0 4.5 9.6 9.5 8.2 11.6 0.9 9.5 2.7 12.4 13.4 15.8 15.4 2.1 8.8 12.1 11.2 14.7 4.5 16.0 10.0 9.6 7.0 11.1 6.5 6.1 10.3 5.8 9.6 8.4 13.2 6.1 12.9 11.6 3.4 9.9 10.0 11.1 6.1 34.0 22.6 0.2 11.9 8.3 16.3 8.0 14.5 2.5 2.2 15.6 17.5 1.6 22.1 13.8 14.7 31.6 10.9 25.0 1.9 0.1 11.1 27.5 32.3 31.2 10.4 11.1 2.5 12.1 14.9 4.5 18.6 9.3 8.4 2.8 1.4 5.4 9.9 48.1 5.4 9.8 23.0 11.8 1.3 7.7 19.3 6.7 7.4 37.8 8.1 35.9 56.0 3.3 30.1 50.2 16.7 3.8 24.5 1.5 26.5 6.5 12.0 1.9 9.8 5.9 4.6 10.0 5.9 1.9 0.3 0.9 0.4 0.2 0.2 0.1 0.3 0.1 0.1 0.4 1.4 0.4 4.3 0.5 0.3 0.1 0.0 0.3 10.1 11.2 12.0 12.0 9.5 8.2 12.4 13.4 11.2 10.3 13.2 11.1 30.8 28.9 13.4 157.7 3.5 32.8 28.8 31.1 35.3 51.5 58.3 33.4 30.8 5.7 30.2 22.0 91.8 33.7 8.0 10.7 1.9 16.6 27.6 79.7 39.6 26.1 35.0 7.8 239.4 11.2 20.3 25.2 11.2 91.3 0.0 106.5 52.5 1.5 6.5 75.7 194.6 21.1 20.3 6.6 8.3 53.4 18.0 8.3 21.4 245.4 8.5 45.6 14.4 237.7 261.0 29.1 12.9 13.5 4.3 70.9 5.3 21.8 55.4 36.1 0.0 20.4 27.6 4.0 17.2 17.9 32.0 27.5 6.4 20.9 24.5 51.5 IGF2 "C11orf43, FLJ44734, IGF-II" ENSG00000167244 "Insulin like growth factor 2" P01344 11 2129112-2141238 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Carbohydrate metabolism, Glucose metabolism, Osteogenesis" "Growth factor, Hormone, Mitogen" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "placenta: 2749.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1104.3;Extravillous trophoblasts: 3196.3;Leydig cells: 3007.5;Peritubular cells: 643.9;Syncytiotrophoblasts: 1612.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 86.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 862.0;Hep G2: 600.5;LHCN-M2: 333.7;RH-30: 408.5;SH-SY5Y: 495.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007556, HPA007993" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 609000000 1200000000 "Cluster 28: Placenta - Pregnancy" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "HPA007556: AB_2667860, HPA007993: AB_1851474" "unprognostic (1.54e-1)" "unprognostic (1.65e-2)" "unprognostic (1.31e-1)" "unprognostic (7.08e-2)" "unprognostic (2.30e-3)" "unprognostic (2.59e-1)" "prognostic favorable (7.12e-4)" "unprognostic (7.92e-2)" "unprognostic (2.59e-2)" "unprognostic (1.68e-2)" "unprognostic (3.69e-2)" "unprognostic (1.85e-1)" "unprognostic (1.79e-3)" "unprognostic (2.00e-2)" "unprognostic (8.98e-2)" "unprognostic (8.93e-3)" "unprognostic (5.78e-2)" 99.7 58.4 5.5 9.2 32.6 0.9 41.8 12.6 86.0 75.5 236.8 22.3 4.7 75.2 52.7 18.8 128.4 34.8 91.7 6.5 7.1 31.8 305.9 9.8 3.4 20.2 6.6 117.8 37.5 5.2 25.4 2749.2 10.1 14.5 4.8 0.5 11.6 15.2 82.1 8.4 10.9 14.7 13.0 14.4 11.9 23.7 10.9 3.4 12.4 114.0 4.7 24.2 23.6 9.0 0.0 2.8 0.3 0.6 0.2 0.3 1.8 112.8 1.3 3.6 0.4 862.0 0.4 0.1 8.4 0.0 2.1 0.1 0.9 7.0 7.9 0.1 0.5 0.2 0.2 600.5 143.4 0.7 0.0 174.7 0.5 0.7 0.2 0.1 1.4 0.0 0.3 0.0 333.7 2.2 0.1 0.8 1.2 0.2 1.5 0.1 408.5 0.9 0.0 0.9 32.7 495.6 0.7 0.1 0.0 83.0 4.2 0.0 0.4 0.2 20.1 0.2 0.0 0.1 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 32.6 12.6 86.0 6.5 7.1 20.2 6.6 10.1 13.0 10.9 9.0 40.6 3.2 3.1 0.0 2.6 5.4 0.5 0.5 0.6 0.4 0.0 0.0 6.5 8.6 0.9 3.7 0.0 1104.3 0.0 0.0 0.0 0.0 13.1 0.0 0.0 498.4 0.0 16.0 0.0 0.0 3196.3 334.2 0.0 0.0 0.0 0.0 171.4 494.9 218.2 0.0 0.0 0.0 0.0 11.6 5.5 91.1 3007.5 3.4 3.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 643.9 0.0 1.1 0.0 0.0 0.9 0.5 65.7 33.5 37.5 3.8 6.3 1.5 4.1 1612.9 1.8 0.0 0.0 0.4 IGFBP7 "FSTL2, IGFBP-7, MAC25, PSF" ENSG00000163453 "Insulin like growth factor binding protein 7" Q16270 4 57030773-57110385 "Disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 11440.4;Peritubular cells: 11731.6;Sertoli cells: 8184.6;Smooth muscle cells: 4434.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 21.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 693.6;BJ hTERT+: 643.1;hTERT-RPE1: 1471.3;RPTEC TERT1: 682.7;TIME: 1009.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002196, CAB020668" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 30300000 190000000 "Cluster 52: Eosinophils - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "CAB020668: , HPA002196: AB_1079107" "unprognostic (2.76e-1)" "unprognostic (1.39e-2)" "unprognostic (6.82e-2)" "unprognostic (5.97e-3)" "unprognostic (3.86e-1)" "unprognostic (3.18e-1)" "unprognostic (2.96e-3)" "unprognostic (1.02e-1)" "unprognostic (2.62e-1)" "unprognostic (1.01e-2)" "unprognostic (2.57e-1)" "unprognostic (6.65e-2)" "unprognostic (2.28e-1)" "unprognostic (2.62e-3)" "unprognostic (1.78e-1)" "unprognostic (3.58e-1)" "unprognostic (7.55e-2)" 833.0 374.9 99.4 151.1 124.0 44.2 583.2 112.7 149.7 640.3 1299.1 473.1 105.6 653.2 260.4 115.3 618.1 405.7 1117.2 132.7 143.8 1298.6 283.2 532.4 133.1 185.2 138.7 359.1 270.1 77.2 246.0 66.6 146.4 506.0 83.2 4.7 193.7 659.0 185.6 193.6 259.6 334.9 136.8 436.9 267.4 259.2 187.9 48.9 995.3 91.8 81.9 546.4 494.0 132.6 1.3 4.8 1.1 0.0 134.8 50.4 4.7 693.6 643.1 59.2 19.0 2.8 0.1 0.3 433.7 33.5 35.3 70.2 0.7 111.1 15.7 1.3 5.4 2.5 78.7 0.5 207.7 17.1 17.9 234.7 55.8 96.8 26.2 1471.3 138.2 0.6 0.5 0.9 142.8 0.0 0.5 74.5 5.9 0.0 1.3 13.4 0.4 2.8 682.7 0.0 1.0 1.8 130.2 9.5 0.0 276.3 1.8 64.6 1009.4 60.5 46.4 7.8 114.8 41.1 0.4 1.4 159.2 58.3 1.8 2.0 3.9 21.7 0.1 4.1 0.1 0.0 0.0 0.0 10.7 0.0 0.0 0.1 0.3 10.8 4.5 0.4 0.1 1.7 99.4 124.0 112.7 149.7 132.7 143.8 185.2 138.7 146.4 136.8 187.9 132.6 2254.8 112.2 20.2 164.9 16.2 238.5 127.2 300.5 24.5 5.9 27.7 53.5 148.2 20.0 90.6 2087.4 22.9 6.6 76.9 1.4 516.5 2455.3 75.9 1235.5 702.2 2740.1 1.2 82.7 0.7 15.1 8.3 1435.9 29.0 381.3 15.8 1205.0 3079.4 16.4 26.5 0.0 3.7 1.0 61.1 101.9 375.7 335.4 11440.4 70.4 944.5 151.8 41.8 17.1 345.0 11.6 0.8 84.6 1.5 11731.6 11.0 113.3 0.0 692.2 731.0 12.5 8184.6 155.0 4434.0 36.6 38.6 9.9 179.1 5.7 51.3 759.1 2.5 64.0 IGHD "FLJ00382, FLJ46727, MGC29633" ENSG00000211898 "Immunoglobulin heavy constant delta" P01880 14 105836765-105845678 "Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 330.9" "Group enriched" "Detected in some" 47 "B-cells: 261.8;Plasma cells: 588.1;T-cells: 474.2" "Cancer enhanced" "Detected in many" "lung cancer: 58.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 63 "memory B-cell: 279.1;naive B-cell: 815.9" "Lineage enriched" "Detected in many" 93 "B-cells: 815.9" "Group enriched" "Detected in some" 7 "Daudi: 82.3;U-698: 95.8" CAB012703 Approved "Immunoglobulin genes" NA NA 14000000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" "CAB012703: AB_10554307" "prognostic favorable (1.49e-6)" "unprognostic (1.84e-2)" "unprognostic (3.99e-2)" "unprognostic (9.54e-2)" "unprognostic (3.06e-2)" "unprognostic (2.08e-3)" "unprognostic (4.63e-2)" "unprognostic (3.28e-1)" "unprognostic (8.18e-2)" "unprognostic (6.16e-2)" "unprognostic (1.75e-1)" "unprognostic (1.25e-1)" "unprognostic (2.13e-3)" "unprognostic (5.76e-2)" "unprognostic (2.64e-1)" "unprognostic (3.82e-3)" "unprognostic (4.30e-2)" 2.8 0.4 0.0 35.4 0.0 39.2 9.3 0.0 0.4 0.9 0.0 2.2 3.4 5.0 0.2 2.8 0.6 19.0 5.7 0.0 0.0 2.1 3.5 34.1 111.6 0.2 0.0 0.3 0.4 0.2 0.0 0.3 0.0 6.4 1.9 0.0 67.1 1.2 0.4 1.5 17.6 0.9 0.0 146.7 43.3 0.3 0.1 8.3 1.3 0.0 330.9 20.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 82.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 12.4 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 95.8 0.0 0.0 0.0 2.7 0.5 0.3 0.4 0.3 0.2 279.1 0.3 0.8 0.7 815.9 1.0 0.3 3.3 0.3 0.5 8.7 0.4 39.2 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 0.0 261.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.6 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 9.3 0.0 0.0 0.0 0.1 0.0 0.0 2.5 0.0 1.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.7 0.0 9.2 0.0 0.0 0.0 0.0 0.0 588.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 474.2 0.0 0.0 0.0 IGHJ5 ENSG00000242472 "Immunoglobulin heavy joining 5" 14 105863814-105863862 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adipose tissue: 33.5;breast: 73.2;intestine: 72.3;prostate: 32.7" "Cell type enriched" "Detected in single" 397 "Plasma cells: 39.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 263 "memory B-cell: 1081.0" "Lineage enriched" "Detected in many" 263 "B-cells: 1081.0" "Group enriched" "Detected in some" 11 "HL-60: 10.5;REH: 14.0;RH-30: 18.0" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" 33.5 0.0 0.7 0.0 3.7 0.0 73.2 0.7 2.0 0.0 2.0 72.3 0.0 0.0 0.0 0.2 0.0 0.0 1.6 0.9 4.2 4.5 29.4 17.1 0.0 3.1 1.0 0.0 4.7 0.0 0.0 0.0 1.9 32.7 0.2 0.2 0.0 0.0 0.0 7.9 0.0 0.0 1.6 0.0 0.0 0.4 1.3 0.0 4.8 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.6 2.1 1.2 0.7 1081.0 0.4 0.6 4.1 0.0 2.6 0.9 2.3 0.7 0.6 0.0 1.1 316.0 0.7 3.7 0.7 2.0 0.9 4.2 3.1 1.0 1.9 1.6 1.3 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV1-3 VI-3B ENSG00000211935 "Immunoglobulin heavy variable 1-3" A0A0C4DH29 14 106005095-106005574 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 223.2;lymphoid tissue: 629.4" "Cell type enriched" "Detected in some" 335 "Plasma cells: 13473.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "memory B-cell: 52.8;naive B-cell: 27.8" "Lineage enriched" "Detected in many" 9 "B-cells: 52.8" "Cell line enriched" "Detected in some" 11 "Karpas-707: 148.5" "Immunoglobulin genes" NA NA 2600000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.39e-2)" "unprognostic (3.81e-3)" "unprognostic (2.96e-2)" "unprognostic (4.93e-2)" "unprognostic (7.41e-3)" "unprognostic (2.42e-1)" "unprognostic (7.85e-2)" "unprognostic (5.60e-2)" "unprognostic (3.07e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (5.67e-7)" "unprognostic (7.02e-2)" "unprognostic (4.31e-1)" "unprognostic (1.75e-1)" "unprognostic (3.26e-1)" 10.6 59.3 0.0 207.8 0.0 36.4 46.7 0.0 0.5 41.6 0.3 193.3 218.5 4.8 15.3 45.5 6.5 85.4 3.2 0.0 0.1 8.2 8.9 40.9 171.8 0.2 0.0 8.4 7.0 0.3 0.6 0.1 0.1 6.0 223.2 0.0 120.6 23.5 0.6 0.9 140.9 11.2 0.0 246.6 189.1 0.4 0.1 57.8 24.2 0.0 629.4 92.1 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 14.1 1.0 148.5 0.0 0.0 0.8 1.1 0.1 0.0 0.0 0.0 0.7 0.7 0.0 0.0 10.0 8.9 0.1 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.7 0.0 2.8 1.4 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 52.8 0.6 0.2 0.0 27.8 1.6 0.5 0.0 0.0 0.0 5.8 1.7 6.1 0.0 0.0 0.0 0.5 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 40.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 27.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13473.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 4.5 0.0 0.0 0.0 IGHV1-45 ENSG00000211961 "Immunoglobulin heavy variable 1-45" A0A0A0MS14 14 106506996-106507491 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 18.9;lymphoid tissue: 30.3;stomach 1: 17.5" "Cell type enriched" "Detected in single" 20 "Plasma cells: 2.0" "Cancer enriched" "Detected in many" 7 "lung cancer: 15.4" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "U-266/70: 1.2;U-266/84: 1.3" "Immunoglobulin genes" NA NA 380000000 "Cluster 32: T-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.57e-4)" "unprognostic (5.07e-3)" "unprognostic (2.12e-3)" "unprognostic (1.46e-1)" "unprognostic (7.64e-3)" "unprognostic (2.90e-1)" "unprognostic (3.50e-2)" "unprognostic (3.16e-1)" "unprognostic (1.48e-1)" "unprognostic (1.05e-1)" "unprognostic (4.05e-1)" "unprognostic (1.28e-3)" "unprognostic (2.94e-2)" "unprognostic (2.87e-1)" "unprognostic (2.32e-1)" "unprognostic (3.16e-1)" 0.2 0.1 0.0 3.7 0.0 1.8 18.9 0.0 0.0 0.3 0.0 4.5 1.1 0.5 0.0 6.4 0.2 0.6 0.1 0.0 0.0 0.2 0.2 3.5 7.6 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.3 6.1 0.0 11.5 0.0 0.0 0.1 2.3 0.7 0.0 6.9 17.5 0.1 0.0 2.9 0.3 0.0 30.3 4.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 1.1 0.6 0.3 0.0 1.1 0.7 0.7 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV1-58 ENSG00000211968 "Immunoglobulin heavy variable 1-58" A0A0C4DH39 14 106622357-106622855 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "urinary bladder: 204.7" "Group enriched" "Detected in some" 17 "B-cells: 2.4;Plasma cells: 1.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 49 "memory B-cell: 8.7;naive B-cell: 12.7" "Lineage enriched" "Detected in single" 58 "B-cells: 12.7" "Cell line enhanced" "Detected in single" "MOLT-4: 1.5" "Immunoglobulin genes" NA NA 120000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (9.63e-3)" "unprognostic (6.78e-2)" "unprognostic (5.64e-2)" "unprognostic (4.04e-2)" "prognostic favorable (7.25e-4)" "unprognostic (4.56e-2)" "unprognostic (1.21e-1)" "unprognostic (4.62e-1)" "unprognostic (1.46e-2)" "unprognostic (4.89e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (8.28e-5)" "unprognostic (3.24e-2)" "unprognostic (5.28e-2)" "unprognostic (6.79e-2)" "unprognostic (1.36e-1)" 8.1 3.4 0.0 13.8 0.0 5.9 3.8 0.0 0.0 0.8 0.0 19.5 15.7 0.4 0.0 8.3 1.1 4.7 1.0 0.0 0.0 1.5 1.4 5.4 41.7 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.4 27.8 0.0 23.5 1.9 0.0 0.2 9.8 0.1 0.0 26.2 13.1 0.5 0.0 10.3 1.1 0.0 51.1 204.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV1-69 IGHV1-E ENSG00000211973 "Immunoglobulin heavy variable 1-69" P01742 14 106714684-106715181 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 139.1;lymphoid tissue: 170.2;urinary bladder: 162.6" "Cell type enriched" "Detected in some" 85 "Plasma cells: 231.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 22 "medulla oblongata: 2.5;pons: 3.0" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.5;plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 1.4;HMC-1: 1.0;MOLT-4: 6.2;SCLC-21H: 1.1;U-698: 1.9" "Immunoglobulin genes" NA NA 2700000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.51e-3)" "unprognostic (7.03e-2)" "prognostic favorable (9.56e-5)" "prognostic favorable (8.32e-4)" "unprognostic (1.06e-2)" "unprognostic (1.69e-1)" "unprognostic (1.82e-1)" "unprognostic (3.64e-1)" "unprognostic (1.64e-2)" "unprognostic (1.70e-1)" "unprognostic (3.91e-1)" "prognostic unfavorable (2.77e-7)" "unprognostic (1.28e-1)" "unprognostic (2.95e-1)" "unprognostic (8.20e-2)" "unprognostic (6.82e-2)" 7.7 1.4 0.0 0.0 0.1 0.1 6.5 0.0 0.0 21.4 0.1 56.9 0.0 6.9 0.0 7.0 5.7 77.4 0.7 0.0 0.1 7.0 4.8 18.0 0.0 2.5 0.0 2.0 0.8 1.8 0.5 0.0 3.0 4.6 139.1 0.0 55.9 13.0 0.1 0.5 31.7 6.8 0.0 170.2 31.0 0.1 0.0 0.0 25.2 0.0 0.0 162.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.1 0.1 0.9 0.0 0.0 1.3 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 2.5 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 231.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 IGHV2-70 ENSG00000274576 "Immunoglobulin heavy variable 2-70" P01814 14 106770577-106771020 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "lymphoid tissue: 727.6;stomach 1: 502.1" "Cell type enriched" "Detected in single" 5 "Plasma cells: 2.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 5.2" "Group enriched" "Detected in some" 241 "memory B-cell: 24.6;naive B-cell: 23.5" "Lineage enriched" "Detected in single" 247 "B-cells: 24.6" "Cell line enriched" "Detected in some" 8 "U-698: 12.4" "Immunoglobulin genes" NA NA 170000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (8.01e-3)" "unprognostic (2.93e-2)" "unprognostic (3.56e-3)" "unprognostic (2.38e-2)" "unprognostic (1.12e-2)" "unprognostic (2.30e-1)" "unprognostic (1.76e-1)" "unprognostic (3.14e-1)" "unprognostic (8.29e-2)" "unprognostic (1.49e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (9.44e-6)" "unprognostic (9.10e-2)" "unprognostic (2.50e-1)" "unprognostic (8.93e-2)" "unprognostic (2.91e-1)" 7.3 25.7 0.0 96.2 0.0 69.2 86.1 0.0 5.2 62.3 0.0 86.7 53.2 4.1 0.0 44.3 8.1 37.5 2.5 0.0 1.4 4.8 13.2 69.9 82.7 0.1 1.1 5.0 1.0 0.9 0.3 0.2 0.1 6.8 82.8 0.0 94.5 14.1 0.1 0.9 42.1 2.5 2.2 156.4 502.1 1.2 0.0 59.5 8.5 0.0 727.6 50.4 4.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.4 0.8 0.0 0.0 0.8 0.6 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.1 0.7 0.0 0.1 0.0 12.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.6 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 5.2 0.0 1.4 0.1 1.1 0.1 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV2-70D ENSG00000211974 "Immunoglobulin heavy variable 2-70D" A0A0C4DH43 14 106723574-106724093 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 36.8;lymphoid tissue: 90.8;stomach 1: 47.0" "Cell type enriched" "Detected in single" 10 "B-cells: 1.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 68 "memory B-cell: 9.7;naive B-cell: 3.7" "Lineage enriched" "Detected in single" 97 "B-cells: 9.7" "Cell line enriched" "Detected in single" 7 "MOLT-4: 1.7" "Immunoglobulin genes" NA NA 110000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "unprognostic (5.57e-2)" "unprognostic (9.48e-3)" "prognostic favorable (3.34e-4)" "unprognostic (4.34e-2)" "unprognostic (8.37e-3)" "unprognostic (2.34e-2)" "unprognostic (1.22e-1)" "unprognostic (1.04e-1)" "unprognostic (2.13e-2)" "unprognostic (6.01e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (6.70e-2)" "unprognostic (3.83e-1)" "unprognostic (3.66e-2)" "unprognostic (8.11e-2)" 1.7 0.7 0.0 16.6 0.0 4.1 7.1 0.0 0.0 5.6 0.1 36.8 14.2 1.9 0.0 5.2 4.5 20.9 1.7 0.0 0.0 2.5 2.3 6.2 4.6 0.0 0.0 0.8 0.3 0.1 0.1 0.0 0.0 0.7 33.1 0.0 30.3 0.1 0.0 0.1 21.7 0.6 0.0 41.4 47.0 0.0 0.0 4.5 2.5 0.0 90.8 3.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-20 ENSG00000211946 "Immunoglobulin heavy variable 3-20" A0A0C4DH32 14 106210936-106211453 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 99.2;lymphoid tissue: 216.6;stomach 1: 122.5;urinary bladder: 81.9" "Cell type enriched" "Detected in some" 24 "Plasma cells: 142.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 242 "memory B-cell: 28.5;naive B-cell: 19.8" "Lineage enriched" "Detected in single" 286 "B-cells: 28.5" "Cell line enhanced" "Detected in single" "Daudi: 1.2" "Immunoglobulin genes" NA NA 2200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.56e-5)" "unprognostic (2.30e-1)" "unprognostic (9.51e-2)" "unprognostic (1.45e-2)" "prognostic favorable (2.93e-4)" "unprognostic (1.35e-2)" "unprognostic (2.37e-1)" "unprognostic (2.45e-1)" "unprognostic (2.62e-1)" "unprognostic (2.42e-1)" "unprognostic (2.93e-1)" "prognostic unfavorable (2.10e-4)" "unprognostic (2.09e-1)" "unprognostic (1.87e-1)" "unprognostic (1.19e-1)" "unprognostic (1.76e-1)" 2.8 2.1 0.0 36.3 0.2 22.6 23.7 0.0 0.1 17.4 0.2 64.8 99.2 1.8 0.0 10.1 2.2 20.7 3.1 0.0 0.0 1.5 4.7 10.5 58.0 0.1 0.0 2.7 0.4 0.1 0.2 0.0 0.0 1.2 62.5 0.0 43.1 1.4 0.0 0.3 37.7 2.0 0.0 59.6 122.5 1.1 0.0 16.6 2.8 0.0 216.6 81.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.5 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 142.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 IGHV3-35 ENSG00000211957 "Immunoglobulin heavy variable 3-35 (non-functional)" A0A0C4DH35 14 106389392-106389858 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 14.1;lymphoid tissue: 12.8;salivary gland: 7.6;stomach 1: 16.7;urinary bladder: 20.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "memory B-cell: 3.7" "Lineage enriched" "Detected in single" 35 "B-cells: 3.7" "Cell line enriched" "Detected in single" 6 "MOLT-4: 1.3" "Immunoglobulin genes" NA NA 19000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.39e-3)" "unprognostic (9.98e-2)" "unprognostic (1.16e-2)" "unprognostic (1.60e-2)" "prognostic favorable (2.53e-4)" "unprognostic (1.06e-1)" "unprognostic (4.74e-1)" "unprognostic (3.44e-1)" "unprognostic (2.37e-1)" "unprognostic (3.21e-1)" "unprognostic (4.29e-6)" "unprognostic (4.60e-2)" "unprognostic (1.60e-1)" "unprognostic (1.33e-1)" "unprognostic (8.59e-2)" 0.1 0.1 0.0 12.8 0.0 3.3 1.1 0.0 0.0 2.8 0.0 10.3 14.1 0.4 0.0 0.5 1.1 1.1 0.5 0.0 0.0 0.1 0.7 2.4 1.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 11.1 0.0 7.6 0.5 0.0 0.2 6.0 0.6 0.0 5.3 16.7 0.0 0.0 0.0 0.0 0.0 2.2 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-38 ENSG00000211958 "Immunoglobulin heavy variable 3-38 (non-functional)" A0A0C4DH36 14 106410493-106411021 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 9.9;lymphoid tissue: 10.4;stomach 1: 5.9;urinary bladder: 7.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "memory B-cell: 3.4;naive B-cell: 1.5" "Lineage enriched" "Detected in single" 34 "B-cells: 3.4" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 2900000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "unprognostic (1.03e-5)" "unprognostic (5.11e-2)" "unprognostic (3.29e-3)" "unprognostic (1.02e-1)" "unprognostic (1.31e-3)" "unprognostic (8.40e-2)" "unprognostic (3.54e-2)" "unprognostic (2.05e-1)" "unprognostic (1.98e-1)" "unprognostic (1.75e-8)" "unprognostic (6.25e-2)" "unprognostic (1.92e-1)" "unprognostic (2.99e-1)" "unprognostic (2.52e-1)" 0.3 0.1 0.0 5.9 0.0 1.6 3.3 0.0 0.0 1.4 0.0 7.7 9.9 0.1 0.0 0.9 0.1 0.9 0.2 0.0 0.0 0.1 0.4 1.8 2.2 0.0 0.0 0.6 0.4 0.0 0.0 0.2 0.0 0.2 7.0 0.0 4.1 0.0 0.0 0.2 5.8 0.0 0.0 4.4 5.9 0.7 0.0 0.0 0.0 0.0 10.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-43 ENSG00000232216 "Immunoglobulin heavy variable 3-43" A0A0B4J1X8 14 106470264-106470800 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 211.9;stomach 1: 312.2;urinary bladder: 153.0" "Cell type enriched" "Detected in some" 28 "Plasma cells: 557.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 321 "memory B-cell: 29.4;naive B-cell: 39.0" "Lineage enriched" "Detected in single" 366 "B-cells: 39.0" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.8;SH-SY5Y: 2.3" "Immunoglobulin genes" NA NA 4000000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.31e-4)" "unprognostic (2.22e-2)" "prognostic favorable (1.46e-4)" "unprognostic (4.87e-3)" "prognostic favorable (8.20e-4)" "unprognostic (2.36e-1)" "unprognostic (1.34e-1)" "unprognostic (4.63e-1)" "unprognostic (7.27e-3)" "unprognostic (4.50e-2)" "unprognostic (8.73e-2)" "prognostic unfavorable (2.40e-5)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "unprognostic (1.29e-1)" "unprognostic (1.75e-2)" 9.3 2.3 0.0 23.7 0.3 11.5 43.7 0.0 0.3 46.0 0.0 101.8 102.5 2.0 0.0 10.2 3.5 10.7 0.4 0.0 0.0 2.7 9.8 10.8 4.3 0.7 0.0 4.2 2.2 1.0 0.3 0.1 0.2 2.7 66.1 0.0 58.1 5.4 0.1 1.0 48.3 4.4 0.0 83.7 312.2 0.2 0.1 0.0 3.8 0.0 211.9 153.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.5 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 29.4 0.0 0.0 0.0 39.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.3 0.0 0.3 0.0 0.0 0.7 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 557.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 IGHV3-48 ENSG00000211964 "Immunoglobulin heavy variable 3-48" P01763 14 106537810-106538344 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 516.4;lymphoid tissue: 858.8;stomach 1: 404.9" "Cell type enriched" "Detected in some" 100 "Plasma cells: 5878.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 527 "memory B-cell: 187.1;naive B-cell: 97.5" "Lineage enriched" "Detected in single" 693 "B-cells: 187.1" "Cell line enhanced" "Detected in some" "SCLC-21H: 1.5;SH-SY5Y: 1.6" "Immunoglobulin genes" NA NA 49000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (9.19e-3)" "unprognostic (1.87e-2)" "unprognostic (5.12e-2)" "unprognostic (9.07e-3)" "unprognostic (1.77e-1)" "prognostic favorable (1.56e-5)" "unprognostic (1.23e-1)" "unprognostic (9.59e-2)" "unprognostic (2.65e-1)" "unprognostic (4.02e-2)" "unprognostic (2.64e-1)" "unprognostic (2.44e-1)" "prognostic unfavorable (4.88e-8)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" 8.7 22.9 0.0 232.6 0.0 81.2 56.4 0.0 1.3 25.9 0.2 434.1 516.4 8.1 0.1 33.4 12.1 38.6 6.9 0.0 0.0 10.8 18.6 32.3 125.3 0.3 0.0 12.2 8.8 0.9 0.9 0.1 0.7 6.8 253.2 0.0 164.6 16.0 0.6 1.6 134.4 17.7 0.1 271.1 404.9 27.9 0.0 36.3 16.0 0.0 858.8 248.6 7.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.9 0.4 0.0 0.0 0.0 0.8 0.9 0.0 0.0 1.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 187.1 0.0 0.0 0.1 97.5 0.0 0.1 0.1 0.0 0.0 0.0 0.2 22.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.0 0.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 58.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.7 17.9 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5878.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 IGHV3-64 ENSG00000223648 "Immunoglobulin heavy variable 3-64" A0A075B6Q5 14 106657725-106658258 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 17.9;lymphoid tissue: 32.1;salivary gland: 21.0" "Cell type enriched" "Detected in some" 38 "Plasma cells: 88.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 19 "memory B-cell: 11.1" "Lineage enriched" "Detected in single" 111 "B-cells: 11.1" "Cell line enhanced" "Detected in single" "HL-60: 1.1" "Immunoglobulin genes" NA NA 4300000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.09e-6)" "unprognostic (6.52e-2)" "unprognostic (2.11e-3)" "unprognostic (3.10e-2)" "unprognostic (1.39e-3)" "unprognostic (1.40e-1)" "unprognostic (2.06e-1)" "unprognostic (8.01e-2)" "unprognostic (2.13e-2)" "unprognostic (2.33e-1)" "unprognostic (2.52e-1)" "prognostic unfavorable (3.93e-5)" "unprognostic (1.58e-1)" "unprognostic (1.85e-1)" "unprognostic (3.86e-2)" "unprognostic (1.07e-2)" 1.7 0.1 0.0 2.0 0.0 8.6 7.2 0.0 0.4 0.7 0.0 17.9 6.9 0.9 0.0 1.2 1.9 4.1 1.2 0.0 0.0 0.8 2.2 4.3 0.0 0.1 0.0 3.3 3.6 0.0 0.1 0.0 0.0 0.5 1.2 0.0 21.0 0.4 0.0 0.1 11.3 1.3 0.0 32.1 6.0 0.0 0.0 0.0 1.5 0.0 0.0 3.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 IGHV3-64D ENSG00000282639 "Immunoglobulin heavy variable 3-64D" A0A0J9YX35 14 106088122-106088573 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 145.2;lymphoid tissue: 272.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 301 "memory B-cell: 43.3;naive B-cell: 18.7" "Lineage enriched" "Detected in single" 420 "B-cells: 43.3" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 2500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 7: Non-specific - Mitochondria" 8.3 0.5 0.2 140.3 0.1 10.9 84.2 0.0 0.8 12.9 0.3 130.9 20.4 3.3 1.4 35.4 7.8 46.3 4.8 0.5 0.0 1.5 4.2 36.7 48.8 0.1 0.0 5.1 8.1 0.1 0.1 0.1 0.0 4.1 145.2 0.0 28.9 11.5 0.0 3.8 68.8 3.6 0.1 67.4 74.8 0.5 0.0 16.5 2.9 0.0 272.7 40.5 1.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.3 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.7 0.2 0.1 0.0 0.8 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-72 ENSG00000225698 "Immunoglobulin heavy variable 3-72" A0A0B4J1Y9 14 106790691-106791233 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 75.7;lymphoid tissue: 121.6;urinary bladder: 101.3" "Cell type enriched" "Detected in some" 271 "Plasma cells: 3507.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 5 "memory B-cell: 52.4" "Lineage enriched" "Detected in many" 50 "B-cells: 52.4" "Cell line enhanced" "Detected in some" "NB-4: 1.3;RH-30: 1.3;RPMI-8226: 1.2;TIME: 2.2;U-698: 5.8" "Immunoglobulin genes" NA NA 9600000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (9.10e-6)" "unprognostic (2.18e-2)" "unprognostic (1.32e-2)" "unprognostic (2.93e-2)" "prognostic favorable (8.57e-5)" "unprognostic (9.14e-3)" "unprognostic (3.98e-2)" "unprognostic (1.86e-1)" "unprognostic (9.20e-2)" "unprognostic (1.12e-1)" "unprognostic (6.27e-2)" "prognostic unfavorable (4.40e-4)" "unprognostic (9.29e-2)" "unprognostic (1.29e-1)" "unprognostic (8.81e-2)" "unprognostic (1.32e-1)" 4.8 2.6 0.1 18.4 0.1 15.5 7.0 0.0 0.6 5.2 0.1 75.7 28.4 3.0 2.9 17.4 3.4 0.3 0.3 0.0 0.0 1.9 5.3 8.6 2.7 0.5 0.0 2.3 3.4 0.1 0.2 0.1 0.1 1.9 47.6 0.0 46.6 0.9 0.1 0.3 58.2 5.4 0.1 121.6 29.4 0.0 0.0 2.6 2.2 0.5 12.1 101.3 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 1.3 0.2 0.0 0.0 0.1 1.3 1.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.2 0.1 0.0 0.3 0.0 5.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 52.4 0.1 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.4 0.1 0.1 0.0 0.6 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.1 7.1 0.0 0.0 0.0 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3507.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 IGHV3OR16-13 IGHV3/OR16-13 ENSG00000271178 "Immunoglobulin heavy variable 3/OR16-13 (non-functional)" 16 33827214-33827661 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 32.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "stomach cancer: 4.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 28 "memory B-cell: 18.1" "Lineage enriched" "Detected in single" 181 "B-cells: 18.1" "Cell line enriched" "Detected in some" 818 "Daudi: 1604.0" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (7.59e-4)" "unprognostic (4.14e-2)" "unprognostic (1.47e-2)" "prognostic favorable (3.23e-5)" "unprognostic (1.34e-1)" "unprognostic (2.50e-2)" "unprognostic (2.19e-1)" "unprognostic (2.01e-1)" "unprognostic (3.26e-5)" "unprognostic (6.83e-2)" "unprognostic (1.71e-1)" "unprognostic (3.09e-1)" "unprognostic (3.04e-1)" 0.2 0.0 0.1 5.3 0.0 0.6 0.4 0.0 0.1 1.3 0.0 6.7 6.0 0.0 0.0 0.3 0.2 0.4 0.0 0.0 0.0 0.2 0.3 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.9 0.0 7.0 0.0 0.0 0.0 4.0 0.1 0.0 32.2 4.2 0.0 0.0 1.0 0.3 0.0 10.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1604.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3OR16-9 IGHV3/OR16-9 ENSG00000270472 "Immunoglobulin heavy variable 3/OR16-9 (non-functional)" 16 32066065-32066358 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 73.2;lymphoid tissue: 88.5;stomach 1: 79.0;urinary bladder: 54.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 136 "memory B-cell: 20.0;naive B-cell: 7.1" "Lineage enriched" "Detected in single" 200 "B-cells: 20.0" "Not detected" "Not detected" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "unprognostic (1.32e-3)" "unprognostic (8.31e-2)" "unprognostic (2.49e-3)" "prognostic favorable (1.29e-4)" "unprognostic (2.29e-1)" "unprognostic (5.22e-2)" "unprognostic (1.91e-1)" "unprognostic (1.31e-1)" "unprognostic (1.01e-5)" "unprognostic (1.57e-1)" "unprognostic (1.38e-1)" "unprognostic (2.85e-1)" "unprognostic (1.55e-1)" 11.1 9.8 0.1 32.9 0.0 13.7 17.1 0.3 0.6 8.3 0.0 73.2 45.8 0.9 0.0 26.5 1.5 8.3 2.9 0.0 0.1 0.8 3.7 9.1 13.0 0.6 0.0 6.2 1.3 0.1 0.0 0.0 0.4 1.1 37.7 0.0 49.3 0.0 0.0 0.0 38.6 0.3 0.4 27.0 79.0 0.3 0.1 8.6 0.1 0.0 88.5 54.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.3 0.6 0.0 0.1 0.6 0.0 0.4 0.4 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV4-59 ENSG00000224373 "Immunoglobulin heavy variable 4-59" P01825 14 106627249-106627825 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 525.9;lymphoid tissue: 911.2;urinary bladder: 702.5" "Cell type enriched" "Detected in some" 301 "Plasma cells: 12374.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "spinal cord: 2.0" "Group enriched" "Detected in some" 37 "memory B-cell: 169.0;naive B-cell: 77.2" "Lineage enriched" "Detected in many" 51 "B-cells: 169.0" "Cell line enhanced" "Detected in some" "MOLT-4: 8.1;SCLC-21H: 2.0;SH-SY5Y: 4.2" "Immunoglobulin genes" NA NA 5500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.62e-5)" "unprognostic (3.95e-2)" "unprognostic (7.25e-3)" "unprognostic (9.13e-2)" "unprognostic (1.13e-2)" "prognostic favorable (9.18e-5)" "unprognostic (2.88e-2)" "unprognostic (3.55e-1)" "unprognostic (2.16e-1)" "unprognostic (3.22e-2)" "unprognostic (2.22e-1)" "unprognostic (3.68e-1)" "prognostic unfavorable (1.41e-7)" "unprognostic (6.04e-2)" "unprognostic (2.24e-1)" "unprognostic (1.94e-1)" "unprognostic (1.76e-1)" 23.9 3.2 0.0 260.5 0.3 95.5 89.3 0.0 1.1 40.4 0.8 525.9 301.0 12.1 2.7 89.6 17.9 168.0 27.9 0.0 0.6 13.8 20.6 89.9 148.0 0.3 0.1 23.5 10.3 1.7 1.5 0.3 0.2 12.6 456.0 0.0 225.7 8.8 0.5 3.6 222.6 19.5 2.0 465.3 260.5 15.0 0.2 86.4 44.1 0.0 911.2 702.5 10.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 1.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.8 0.0 0.0 0.0 8.1 1.0 0.3 0.3 0.0 0.8 1.0 0.7 0.0 0.0 2.0 4.2 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.0 0.4 0.4 0.1 1.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 169.0 0.0 0.2 1.4 77.2 0.1 0.0 0.0 0.0 0.1 3.3 0.1 11.9 0.0 0.3 0.0 1.1 0.0 0.6 0.3 0.1 0.2 2.0 0.2 0.3 0.0 0.0 0.6 0.0 41.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 11.2 0.0 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12374.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 3.6 0.0 0.5 0.0 IGKV1D-12 ENSG00000278857 "Immunoglobulin kappa variable 1D-12" P01611 2 90159840-90160335 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.6;lymphoid tissue: 47.5;salivary gland: 34.6" "Cell type enriched" "Detected in some" 178 "Plasma cells: 232.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 34 "memory B-cell: 13.0;naive B-cell: 12.2" "Lineage enriched" "Detected in single" 35 "B-cells: 13.0" "Cell line enhanced" "Detected in single" "RH-30: 2.2" HPA048721 Approved "Immunoglobulin genes" NA NA 12000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (1.94e-4)" "unprognostic (9.04e-4)" "unprognostic (3.42e-2)" "prognostic favorable (3.23e-4)" "unprognostic (3.09e-2)" "unprognostic (4.66e-2)" "unprognostic (1.34e-1)" "unprognostic (1.33e-3)" "unprognostic (1.61e-1)" "unprognostic (1.73e-1)" "unprognostic (1.29e-1)" "unprognostic (1.25e-1)" 1.7 0.3 0.0 9.6 0.0 0.9 7.6 0.0 0.2 3.0 0.0 26.6 1.6 1.3 0.0 2.2 1.8 0.0 0.3 0.0 0.0 1.7 1.0 11.6 12.5 0.1 0.0 0.2 0.4 0.0 0.2 0.1 0.1 1.1 9.1 0.0 34.6 0.3 0.1 0.2 22.7 5.5 0.0 47.5 9.5 0.2 0.0 1.3 4.0 0.0 9.4 2.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.4 0.4 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.1 12.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 232.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-16 ENSG00000241244 "Immunoglobulin kappa variable 1D-16" P01601 2 90100236-90100738 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 79.1;intestine: 92.0;lymphoid tissue: 165.5" "Cell type enriched" "Detected in some" 249 "Plasma cells: 1994.1" "Cancer enhanced" "Detected in many" "lung cancer: 17.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 327 "memory B-cell: 57.6;naive B-cell: 120.1" "Lineage enriched" "Detected in single" 442 "B-cells: 120.1" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 9000000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.41e-4)" "unprognostic (4.41e-3)" "unprognostic (3.96e-3)" "unprognostic (5.39e-2)" "unprognostic (1.35e-3)" "unprognostic (8.61e-2)" "unprognostic (2.92e-1)" "unprognostic (1.27e-1)" "unprognostic (1.54e-2)" "unprognostic (6.61e-3)" "unprognostic (3.25e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (4.37e-1)" "unprognostic (2.38e-1)" "unprognostic (4.66e-2)" "unprognostic (2.84e-1)" 2.4 0.4 0.0 30.2 0.0 15.0 18.9 0.0 0.4 11.0 0.1 92.0 39.0 1.6 0.0 13.8 2.5 79.1 1.3 0.0 0.0 1.7 3.9 10.0 27.5 0.0 0.0 2.5 0.9 0.6 0.1 0.0 0.1 3.6 50.3 0.0 30.3 0.9 0.0 0.2 34.4 1.0 0.3 56.6 26.7 0.4 0.0 9.9 2.7 0.0 165.5 23.5 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 57.6 0.0 0.0 0.1 120.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1994.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 IGKV1D-43 ENSG00000242580 "Immunoglobulin kappa variable 1D-43" A0A0B4J1Z2 2 90209873-90210529 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.9;lymphoid tissue: 4.8;stomach 1: 3.6" "Cell type enriched" "Detected in some" 86 "Plasma cells: 695.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 152 "memory B-cell: 13.3;naive B-cell: 17.0" "Lineage enriched" "Detected in single" 171 "B-cells: 17.0" "Cell line enriched" "Detected in single" 310 "RPMI-8226: 79.1" HPA048721 Approved "Immunoglobulin genes" NA NA 380000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (3.32e-5)" "unprognostic (6.71e-2)" "unprognostic (4.01e-2)" "unprognostic (1.27e-2)" "unprognostic (4.57e-3)" "unprognostic (1.37e-3)" "unprognostic (3.15e-1)" "unprognostic (2.67e-2)" "unprognostic (3.82e-5)" "unprognostic (3.96e-2)" "unprognostic (2.20e-1)" "unprognostic (6.26e-2)" "unprognostic (1.06e-1)" 0.2 0.0 0.0 2.8 0.0 1.3 1.4 0.0 0.0 0.0 0.0 2.7 1.9 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 1.1 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 2.0 0.2 0.0 0.0 2.9 0.0 0.0 1.8 3.6 0.0 0.0 0.5 0.1 0.0 4.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 79.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 695.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGKV1D-8 ENSG00000239819 "Immunoglobulin kappa variable 1D-8" A0A087WSZ0 2 90220727-90221384 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 4.2;lymphoid tissue: 14.2;salivary gland: 5.6" "Cell type enriched" "Detected in some" 29 "Plasma cells: 338.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 323 "memory B-cell: 32.7;naive B-cell: 31.8" "Lineage enriched" "Detected in single" 328 "B-cells: 32.7" "Cell line enriched" "Detected in some" 26 "RPMI-8226: 38.3" HPA048721 Approved "Immunoglobulin genes" NA NA 1900000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.93e-4)" "unprognostic (1.03e-3)" "unprognostic (2.23e-2)" "unprognostic (2.76e-3)" "prognostic favorable (8.80e-5)" "unprognostic (6.07e-2)" "unprognostic (9.76e-3)" "unprognostic (2.67e-1)" "unprognostic (1.61e-1)" "unprognostic (1.63e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.12e-6)" "unprognostic (1.35e-1)" "unprognostic (9.51e-2)" "unprognostic (1.06e-1)" "unprognostic (1.32e-1)" 0.5 0.0 0.0 5.3 0.0 0.7 1.2 0.0 0.0 0.6 0.0 4.2 1.6 0.1 0.0 0.5 0.3 0.0 0.1 0.0 0.0 0.3 0.3 1.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 2.6 0.0 5.6 0.0 0.0 0.0 2.8 0.0 0.0 8.3 1.9 0.0 0.0 1.2 0.6 0.0 14.2 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.3 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.7 0.0 0.0 0.0 31.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 338.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGKV2D-24 ENSG00000241566 "Immunoglobulin kappa variable 2D-24 (non-functional)" A0A075B6R9 2 90004797-90005629 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 19.7;lymphoid tissue: 25.5;urinary bladder: 15.3" "Cell type enriched" "Detected in single" 207 "Plasma cells: 165.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "hippocampal formation: 1.8" "Group enriched" "Detected in some" 48 "memory B-cell: 6.7;naive B-cell: 2.7" "Lineage enriched" "Detected in single" 68 "B-cells: 6.7" "Cell line enriched" "Detected in single" 8 "U-937: 1.0" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.21e-4)" "unprognostic (1.78e-1)" "prognostic favorable (8.07e-4)" "unprognostic (2.09e-2)" "prognostic favorable (2.11e-4)" "unprognostic (2.33e-1)" "unprognostic (2.29e-2)" "unprognostic (4.00e-2)" "unprognostic (1.92e-2)" "unprognostic (3.74e-5)" "unprognostic (7.60e-2)" "unprognostic (1.57e-2)" "unprognostic (3.85e-1)" "unprognostic (3.47e-1)" 0.6 0.8 0.0 4.3 0.0 2.7 6.1 0.0 0.7 0.5 0.0 16.8 19.7 0.1 0.0 1.5 0.4 3.5 0.1 1.8 0.0 0.6 0.5 1.8 6.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.3 7.2 0.0 9.6 0.5 0.0 0.3 7.0 0.1 0.1 25.0 5.2 0.1 0.1 1.7 0.4 0.0 25.5 15.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 1.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 165.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV2D-28 ENSG00000242534 "Immunoglobulin kappa variable 2D-28" P01615 2 89959979-89960754 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 221.6;lymphoid tissue: 462.7;salivary gland: 259.7" "Cell type enriched" "Detected in some" 98 "Plasma cells: 4332.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 224 "memory B-cell: 3054.0;naive B-cell: 2203.9" "Lineage enriched" "Detected in all" 260 "B-cells: 3054.0" "Cell line enhanced" "Detected in some" "HDLM-2: 5.0;RPMI-8226: 2.0;SCLC-21H: 1.9;SH-SY5Y: 4.3;U-698: 4.4" "Immunoglobulin genes" NA NA 3500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.88e-3)" "unprognostic (2.68e-2)" "unprognostic (2.51e-3)" "unprognostic (1.22e-1)" "unprognostic (1.13e-1)" "unprognostic (4.17e-1)" "unprognostic (1.13e-1)" "unprognostic (2.66e-1)" 9.9 4.8 0.1 162.1 0.2 23.3 35.2 0.0 1.5 7.6 0.3 203.7 221.6 8.3 1.2 113.5 14.0 26.1 4.8 0.3 0.4 11.5 13.3 40.6 166.6 0.7 0.2 2.8 1.9 0.1 0.9 0.4 0.4 11.1 65.9 0.0 259.7 19.2 0.3 1.4 143.3 8.7 0.2 462.7 186.4 5.7 0.2 40.9 37.8 0.3 192.0 157.9 8.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 1.1 0.0 0.0 0.0 5.0 0.0 1.4 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.4 0.1 0.0 0.0 0.7 0.0 2.0 0.0 0.0 1.9 4.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.6 1.3 0.0 4.4 0.0 1.1 0.0 11.7 7.8 1.2 1.2 0.5 1.3 3054.0 1.3 0.9 2.0 2203.9 0.2 0.9 2.2 1.0 1.5 1.4 1.3 248.7 0.1 0.2 0.0 1.5 0.3 0.4 0.7 0.2 0.4 0.2 0.2 0.3 0.0 0.0 0.0 0.0 44.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4332.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 31.5 0.0 0.1 0.0 IGKV2D-30 ENSG00000239571 "Immunoglobulin kappa variable 2D-30" A0A075B6S6 2 89936859-89937679 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.3;lymphoid tissue: 33.5;stomach 1: 22.2" "Cell type enriched" "Detected in some" 222 "Plasma cells: 1314.8" "Cancer enhanced" "Detected in some" "stomach cancer: 2.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 379 "memory B-cell: 124.9;naive B-cell: 164.0" "Lineage enriched" "Detected in single" 430 "B-cells: 164.0" "Cell line enriched" "Detected in some" 6 "U-698: 51.7" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.17e-3)" "unprognostic (6.82e-2)" "unprognostic (1.58e-1)" "unprognostic (2.98e-4)" "unprognostic (5.74e-3)" "unprognostic (3.19e-2)" "unprognostic (1.10e-1)" "unprognostic (4.12e-2)" "unprognostic (3.55e-1)" 0.4 0.4 0.0 6.4 0.0 4.3 5.9 0.0 0.1 0.8 0.0 15.3 11.8 0.4 0.0 1.0 0.4 0.8 0.8 0.1 0.1 1.4 0.7 2.8 6.7 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.1 0.5 11.2 0.0 13.0 4.6 0.0 1.2 8.5 2.0 0.0 29.3 22.2 0.1 0.0 1.6 0.8 0.0 33.5 5.6 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 51.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 124.9 0.0 0.1 0.1 164.0 0.0 0.0 0.3 0.1 0.1 0.0 0.1 19.3 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1314.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 IGKV2D-40 ENSG00000251039 "Immunoglobulin kappa variable 2D-40" P01614 2 89851791-89852497 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 123.3" "Cell type enriched" "Detected in some" 489 "Plasma cells: 1517.1" "Cancer enhanced" "Detected in many" "ovarian cancer: 30.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 494 "memory B-cell: 134.9;naive B-cell: 96.8" "Lineage enriched" "Detected in single" 575 "B-cells: 134.9" "Cell line enhanced" "Detected in single" "Daudi: 3.7" "Immunoglobulin genes" NA NA 1900000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.01e-4)" "unprognostic (1.16e-2)" "unprognostic (8.37e-2)" "unprognostic (6.04e-2)" "prognostic favorable (9.78e-7)" "unprognostic (1.87e-1)" "unprognostic (2.29e-1)" "unprognostic (2.32e-2)" "unprognostic (7.79e-2)" "prognostic unfavorable (1.75e-4)" "unprognostic (3.59e-2)" "unprognostic (3.02e-1)" "unprognostic (2.91e-1)" "unprognostic (1.25e-1)" 1.7 1.4 0.0 21.0 0.0 14.8 13.5 0.0 0.1 10.0 0.0 16.6 6.9 3.0 0.0 35.6 14.4 7.7 2.0 0.0 0.0 1.0 2.9 19.5 65.7 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.6 21.8 0.0 32.3 21.7 0.0 0.0 31.2 1.6 0.0 44.8 38.6 0.4 0.0 26.3 5.7 0.0 123.3 34.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 134.9 0.0 0.0 0.0 96.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1517.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGKV3D-7 ENSG00000228325 "Immunoglobulin kappa variable 3D-7" A0A0C4DH55 2 90234812-90235370 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.6;lymphoid tissue: 5.5;stomach 1: 4.4;urinary bladder: 5.5" "Cell type enriched" "Detected in single" 415 "Plasma cells: 207.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 36 "memory B-cell: 2.8;naive B-cell: 4.3" "Lineage enriched" "Detected in single" 44 "B-cells: 4.3" "Cell line enriched" "Detected in some" 12 "RPMI-8226: 48.7" HPA047702 Approved "Immunoglobulin genes" NA NA 3700000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "unprognostic (2.74e-1)" "unprognostic (8.62e-3)" "unprognostic (6.59e-2)" "unprognostic (2.14e-1)" "unprognostic (3.05e-1)" "unprognostic (4.02e-1)" 0.1 0.0 0.0 5.5 0.2 1.3 0.1 0.0 0.1 0.2 0.0 4.0 4.6 0.0 0.0 1.9 0.1 1.5 0.0 0.1 0.1 0.0 0.2 0.5 1.4 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 2.1 0.1 0.0 0.0 4.4 0.0 0.0 3.8 4.4 0.0 0.1 0.2 0.6 0.0 4.3 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 207.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV5-2 "B2, IGKV52" ENSG00000211599 "Immunoglobulin kappa variable 5-2" P06315 2 88897232-88897784 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.9;lymphoid tissue: 83.1" "Cell type enriched" "Detected in some" 193 "Plasma cells: 1664.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "memory B-cell: 21.4;naive B-cell: 17.2" "Lineage enriched" "Detected in many" 21 "B-cells: 21.4" "Group enriched" "Detected in some" 19 "Daudi: 4.2;HDLM-2: 1.8;RPMI-8226: 2.3" "Low region specificity" "Detected in all" "Immunoglobulin genes" NA NA 4700000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.77e-3)" "unprognostic (1.26e-2)" "unprognostic (1.34e-1)" "unprognostic (2.49e-2)" "prognostic favorable (2.12e-4)" "unprognostic (2.37e-1)" "unprognostic (2.26e-1)" "unprognostic (1.29e-1)" "unprognostic (2.55e-1)" "prognostic unfavorable (8.62e-6)" "unprognostic (2.60e-1)" "unprognostic (2.99e-2)" "unprognostic (1.52e-1)" "unprognostic (7.85e-2)" 0.9 0.0 0.0 10.3 0.0 6.4 19.6 0.0 0.0 5.3 0.0 23.3 35.9 0.8 0.0 4.0 0.9 0.9 0.1 0.0 0.0 0.9 1.0 6.3 17.3 0.0 0.0 0.4 0.4 0.5 0.0 0.0 0.0 0.6 11.1 0.0 14.9 1.9 0.0 0.5 14.3 0.2 0.0 23.5 15.3 0.0 0.0 3.0 1.0 0.0 83.1 4.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 0.0 0.0 0.0 17.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1664.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 IGKV6D-21 "A10, IGKV6D21" ENSG00000225523 "Immunoglobulin kappa variable 6D-21 (non-functional)" A0A0A0MT36 2 90021567-90022185 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "intestine: 67.0;lymphoid tissue: 152.7;urinary bladder: 227.3" "Cell type enriched" "Detected in some" 7 "Plasma cells: 234.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 154 "memory B-cell: 14.2;naive B-cell: 16.5" "Lineage enriched" "Detected in single" 166 "B-cells: 16.5" "Not detected" "Not detected" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.95e-4)" "unprognostic (5.47e-3)" "unprognostic (2.85e-3)" "prognostic favorable (5.25e-5)" "unprognostic (1.51e-1)" "unprognostic (1.86e-1)" "unprognostic (2.72e-1)" "unprognostic (3.10e-2)" "prognostic unfavorable (3.45e-7)" "unprognostic (7.23e-2)" "unprognostic (2.00e-1)" "unprognostic (1.24e-1)" "unprognostic (2.07e-1)" 1.1 0.4 0.0 17.2 0.0 17.2 11.8 0.0 0.1 5.4 0.0 67.0 38.8 1.6 0.0 22.1 0.8 2.7 2.1 0.2 0.0 1.6 2.4 6.3 19.8 0.6 0.0 1.1 1.1 0.0 0.0 0.0 0.1 0.8 31.8 0.0 21.1 17.3 0.0 1.2 37.8 1.0 0.0 45.3 13.4 3.4 0.0 9.1 1.4 0.0 152.7 227.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.2 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 234.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGLV10-54 ENSG00000211642 "Immunoglobulin lambda variable 10-54" A0A075B6I4 22 22038643-22215270 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 7 "breast: 121.9;intestine: 324.6;lymphoid tissue: 329.7;salivary gland: 253.6;stomach 1: 194.5" "Cell type enriched" "Detected in some" 17 "Plasma cells: 358.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 2.2" "Group enriched" "Detected in some" 32 "memory B-cell: 60.0;naive B-cell: 35.2" "Lineage enriched" "Detected in many" 41 "B-cells: 60.0" "Cell line enhanced" "Detected in single" "TIME: 2.3" "Immunoglobulin genes" NA NA 54000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (9.35e-5)" "unprognostic (2.65e-2)" "unprognostic (9.06e-2)" "unprognostic (8.71e-3)" "unprognostic (1.29e-1)" "prognostic favorable (8.30e-5)" "unprognostic (1.40e-1)" "unprognostic (1.83e-1)" "unprognostic (5.62e-1)" "unprognostic (1.18e-1)" "unprognostic (3.22e-1)" "unprognostic (2.00e-1)" "prognostic unfavorable (1.48e-5)" "unprognostic (3.33e-1)" "unprognostic (5.57e-2)" "unprognostic (5.17e-2)" "unprognostic (3.86e-1)" 3.6 1.9 0.1 96.4 0.3 33.8 121.9 0.1 2.2 2.0 0.8 324.6 294.8 1.5 0.0 22.5 24.3 21.9 12.0 0.1 0.3 2.5 7.0 22.3 64.7 1.4 0.1 2.6 11.6 0.0 0.4 0.4 0.2 6.4 155.1 0.0 253.6 2.3 0.1 1.0 138.9 12.7 0.2 155.3 194.5 0.4 0.1 22.9 2.5 0.0 329.7 21.8 4.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 60.0 0.0 0.0 0.0 35.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.1 0.3 0.1 2.2 0.1 0.3 1.4 0.1 0.2 0.2 0.1 0.7 0.0 0.0 0.0 0.0 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 358.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGLV3-27 ENSG00000211658 "Immunoglobulin lambda variable 3-27" P01718 22 22668288-22668806 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 401.6" "Cell type enriched" "Detected in some" 135 "Plasma cells: 1406.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 719 "memory B-cell: 194.0;naive B-cell: 367.8" "Lineage enriched" "Detected in single" 941 "B-cells: 367.8" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 720000000 "Cluster 24: B-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.45e-2)" "unprognostic (1.87e-3)" "unprognostic (5.44e-2)" "unprognostic (4.30e-3)" "prognostic favorable (3.60e-7)" "unprognostic (8.55e-2)" "unprognostic (2.16e-1)" "unprognostic (5.91e-2)" "unprognostic (9.56e-2)" "unprognostic (4.55e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (4.95e-9)" "unprognostic (1.82e-2)" "unprognostic (2.09e-1)" "unprognostic (1.90e-1)" "unprognostic (2.07e-1)" 8.8 1.8 0.1 16.4 0.0 29.4 29.7 0.0 0.5 23.7 0.1 56.7 19.3 2.2 0.0 10.3 5.1 10.5 3.1 0.0 0.0 3.7 3.7 29.3 64.3 0.4 0.0 2.9 0.3 0.2 0.4 0.0 0.1 2.4 26.9 0.0 40.6 0.8 0.0 0.5 24.4 0.6 0.0 103.9 59.8 24.2 0.0 47.6 2.8 0.0 401.6 27.4 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.1 0.1 194.0 0.2 0.0 0.3 367.8 0.0 0.0 0.2 0.0 0.1 0.1 0.1 11.8 0.1 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1406.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGLV4-3 ENSG00000211672 "Immunoglobulin lambda variable 4-3" A0A075B6K6 22 22871507-22872035 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "lymphoid tissue: 15.7;stomach 1: 28.9" "Cell type enriched" "Detected in some" 23 "Plasma cells: 50.3" "Cancer enhanced" "Detected in many" "lung cancer: 4.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 98 "memory B-cell: 11.7;naive B-cell: 7.8" "Lineage enriched" "Detected in single" 118 "B-cells: 11.7" "Cell line enriched" "Detected in single" 5 "Daudi: 1.3" "Immunoglobulin genes" NA NA 1600000 "Cluster 37: B-cells - Transcription" "Cluster 4: Stomach - Digestion" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (7.22e-2)" "unprognostic (5.51e-3)" "unprognostic (2.71e-1)" "unprognostic (4.37e-4)" "unprognostic (1.87e-1)" "unprognostic (2.74e-1)" "unprognostic (1.49e-1)" "unprognostic (1.36e-1)" 0.2 0.0 0.0 2.1 0.0 1.4 1.6 0.0 0.0 0.3 0.0 5.1 4.5 0.3 0.0 0.3 0.1 0.4 0.0 0.0 0.0 0.1 0.1 1.0 10.1 0.5 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 3.3 0.0 2.8 0.0 0.0 0.0 3.0 0.0 0.0 5.3 28.9 0.2 0.0 1.4 0.4 0.0 15.7 0.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV4-60 ENSG00000211639 "Immunoglobulin lambda variable 4-60" A0A075B6I1 22 22162199-22162681 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 193.1;lymphoid tissue: 116.3;urinary bladder: 185.2" "Cell type enriched" "Detected in some" 152 "Plasma cells: 1125.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 78 "memory B-cell: 79.4;naive B-cell: 48.9" "Lineage enriched" "Detected in single" 96 "B-cells: 79.4" "Group enriched" "Detected in some" 4 "Daudi: 7.8;HEL: 13.3;U-698: 3.9" "Immunoglobulin genes" NA NA 120000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.57e-4)" "unprognostic (5.46e-3)" "unprognostic (9.43e-3)" "unprognostic (1.26e-2)" "prognostic favorable (1.89e-4)" "unprognostic (3.06e-2)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.81e-1)" "unprognostic (1.29e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (1.87e-6)" "unprognostic (1.78e-1)" "unprognostic (1.08e-1)" "unprognostic (4.19e-1)" "unprognostic (2.60e-1)" 1.8 1.9 0.0 32.9 0.0 18.1 36.6 0.0 0.2 3.3 0.1 70.7 193.1 1.5 0.0 12.3 1.9 3.4 11.4 0.0 0.0 3.1 3.9 43.5 116.3 0.0 0.0 4.6 1.1 0.4 0.2 0.2 0.1 1.1 73.3 0.0 37.9 0.8 0.1 0.1 86.8 2.1 0.0 80.3 37.7 1.7 0.0 18.3 1.7 0.0 112.0 185.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 3.9 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 79.4 0.1 0.0 0.0 48.9 0.0 0.0 0.8 0.0 0.0 0.0 0.4 3.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1125.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGLV5-48 ENSG00000211647 "Immunoglobulin lambda variable 5-48 (non-functional)" A0A075B6I7 22 22352940-22353433 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 3.3;lymphoid tissue: 5.5;urinary bladder: 2.7" "Cell type enriched" "Detected in some" 8 "Plasma cells: 19.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 61 "memory B-cell: 5.4;naive B-cell: 6.7" "Lineage enriched" "Detected in single" 68 "B-cells: 6.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.76e-3)" "unprognostic (1.91e-2)" "unprognostic (9.43e-2)" "unprognostic (3.36e-4)" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" "unprognostic (1.74e-2)" "unprognostic (2.97e-1)" 0.0 0.0 0.0 0.9 0.0 1.3 0.9 0.0 0.6 0.4 0.0 3.3 3.3 0.0 0.0 0.3 0.1 0.3 0.1 0.0 0.0 0.1 0.1 0.3 3.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 1.5 0.0 0.0 0.0 1.3 0.2 0.0 5.5 0.7 0.0 0.0 2.5 0.1 0.0 5.3 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV7-46 ENSG00000211649 "Immunoglobulin lambda variable 7-46" A0A075B6I9 22 22369614-22370087 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 400.6;lymphoid tissue: 459.1;stomach 1: 250.7;urinary bladder: 444.0" "Cell type enriched" "Detected in some" 180 "Plasma cells: 6758.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "hypothalamus: 1.6" "Group enriched" "Detected in some" 377 "memory B-cell: 183.6;naive B-cell: 82.3" "Lineage enriched" "Detected in single" 521 "B-cells: 183.6" "Cell line enhanced" "Detected in some" "Daudi: 8.0;RPMI-8226: 2.8;U-698: 6.6" HPA003182 Approved "Immunoglobulin genes" NA NA 270000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003182: " "prognostic favorable (3.34e-6)" "unprognostic (1.21e-1)" "unprognostic (1.10e-2)" "unprognostic (3.94e-3)" "unprognostic (4.25e-3)" "unprognostic (4.68e-3)" "unprognostic (1.74e-1)" "unprognostic (2.77e-2)" "unprognostic (7.47e-3)" "unprognostic (2.17e-1)" "unprognostic (4.02e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.78e-1)" "unprognostic (1.87e-1)" "unprognostic (2.99e-1)" "unprognostic (2.02e-1)" 15.1 3.8 0.0 59.8 0.3 44.2 171.7 0.1 0.9 4.1 0.1 400.6 162.4 4.4 0.0 43.7 3.0 56.0 5.2 0.0 1.6 5.7 7.7 44.9 82.2 0.4 0.0 9.0 6.2 0.1 0.8 0.1 0.2 2.5 298.6 0.0 107.2 5.2 0.5 0.8 133.1 12.1 0.1 248.1 250.7 0.7 0.2 57.3 8.7 0.0 459.1 444.0 3.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.9 0.3 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.3 0.0 6.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 183.6 0.1 0.0 0.1 82.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 15.2 0.0 0.3 0.1 0.9 0.0 1.6 0.4 0.0 0.2 0.1 0.2 0.4 0.0 0.0 0.0 0.0 37.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 12.8 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6758.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 IGLV9-49 ENSG00000223350 "Immunoglobulin lambda variable 9-49" A0A0B4J1Y8 22 22343187-22343732 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 125.5;lymphoid tissue: 118.0" "Cell type enriched" "Detected in some" 20 "Plasma cells: 46.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 672 "memory B-cell: 70.3;naive B-cell: 88.1" "Lineage enriched" "Detected in single" 747 "B-cells: 88.1" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 43000000 "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.04e-5)" "unprognostic (4.30e-3)" "unprognostic (1.83e-2)" "unprognostic (5.61e-2)" "prognostic favorable (2.00e-5)" "unprognostic (6.29e-2)" "unprognostic (2.69e-2)" "unprognostic (2.01e-1)" "unprognostic (1.27e-2)" "unprognostic (2.81e-1)" "unprognostic (2.13e-1)" "prognostic unfavorable (1.12e-8)" "unprognostic (1.66e-1)" "unprognostic (3.07e-1)" "unprognostic (3.90e-2)" "unprognostic (7.16e-2)" 2.4 125.5 0.0 14.7 0.0 9.8 6.1 0.1 0.5 3.3 0.0 33.6 36.5 2.2 0.0 6.0 3.2 1.1 1.2 0.2 0.0 1.2 4.4 43.8 118.0 0.2 0.0 3.3 1.4 0.0 0.1 0.1 0.2 0.9 15.1 0.0 29.7 1.0 0.1 0.1 28.2 0.4 0.0 65.9 46.3 2.0 0.0 14.0 3.4 0.1 97.9 39.2 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 70.3 0.0 0.0 0.1 88.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.1 0.5 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGSF10 "CMF608, FLJ25972" ENSG00000152580 "Immunoglobulin superfamily member 10" Q6WRI0 3 151425384-151458709 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 17.7" "Cell type enhanced" "Detected in many" "Early spermatids: 170.5;Horizontal cells: 60.6;Late spermatids: 34.1;Microglial cells: 61.8;Syncytiotrophoblasts: 30.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HeLa: 44.1;HL-60: 23.3;REH: 17.2;RPMI-8226: 55.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA012655, HPA012921" Uncertain Approved Vesicles "Secreted - unknown location" NA NA 540000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA012655: , HPA012921: AB_1851526" "unprognostic (1.78e-3)" "unprognostic (2.48e-2)" "unprognostic (1.71e-1)" "unprognostic (3.47e-7)" "unprognostic (1.68e-1)" "unprognostic (2.12e-1)" "unprognostic (9.82e-2)" "unprognostic (8.84e-4)" "unprognostic (9.38e-3)" "unprognostic (1.96e-1)" "unprognostic (5.70e-2)" "unprognostic (2.04e-1)" "unprognostic (7.52e-4)" "unprognostic (6.01e-2)" "unprognostic (8.93e-2)" "unprognostic (4.59e-3)" "unprognostic (7.57e-4)" 3.9 4.0 1.4 0.9 0.7 0.6 6.1 0.3 1.0 0.5 3.2 1.3 0.5 1.4 1.6 2.9 4.3 9.7 4.3 2.8 1.1 0.2 0.3 8.6 1.4 0.1 1.0 17.7 0.7 1.3 1.7 0.7 0.3 0.1 1.3 0.2 5.2 0.2 0.1 1.9 1.2 1.5 0.0 0.9 0.7 0.9 3.6 1.3 1.5 0.5 2.5 2.2 0.3 0.3 0.0 0.1 0.3 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.1 0.0 0.4 0.0 0.0 0.3 0.3 7.5 44.1 0.0 1.6 23.3 0.1 0.4 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 17.2 0.1 55.1 0.1 0.1 1.0 0.0 5.9 0.0 0.0 0.2 0.0 0.2 0.0 0.1 1.1 0.0 0.0 2.4 0.0 0.0 0.2 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.7 0.3 1.0 2.8 1.1 0.1 1.0 0.3 0.0 3.6 0.3 2.0 0.0 0.5 1.0 0.6 2.4 1.2 0.5 2.8 15.8 0.6 0.9 1.6 2.8 6.3 1.8 4.2 21.7 2.7 0.2 0.0 0.1 170.5 11.4 4.0 0.9 6.0 3.4 2.4 1.3 2.9 20.4 0.5 0.5 0.0 0.0 0.0 0.1 1.3 60.6 2.8 0.7 4.1 0.8 3.2 34.1 6.8 2.9 3.6 61.8 1.1 25.6 0.0 0.5 0.7 0.4 0.1 1.2 0.3 0.7 0.0 0.3 12.5 2.4 0.0 0.5 2.2 10.7 7.9 0.8 2.4 30.9 0.6 2.5 0.1 0.2 IL11RA ENSG00000137070 "Interleukin 11 receptor subunit alpha" Q14626 9 34650702-34661902 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Craniosynostosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 57.8;Late spermatids: 97.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 36.8;HSkMC: 38.2" "Low region specificity" "Detected in all" "HPA013162, CAB032830, HPA036652" Supported "Secreted to blood" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB032830: AB_2123745, HPA013162: AB_2668790, HPA036652: AB_2675229" "unprognostic (7.76e-2)" "unprognostic (7.63e-2)" "unprognostic (1.05e-1)" "unprognostic (6.76e-3)" "unprognostic (1.67e-1)" "unprognostic (1.39e-2)" "unprognostic (9.91e-2)" "unprognostic (1.52e-2)" "unprognostic (1.89e-2)" "unprognostic (4.02e-1)" "unprognostic (1.28e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (6.56e-4)" "unprognostic (2.14e-1)" "unprognostic (1.51e-1)" "unprognostic (2.93e-2)" "unprognostic (8.71e-2)" 26.6 14.8 20.0 15.5 22.9 13.7 30.2 23.9 23.8 44.6 17.2 58.0 21.7 32.9 12.2 16.3 36.8 19.5 66.4 20.6 20.4 21.9 50.7 22.6 32.0 21.4 21.5 38.0 12.9 29.2 21.8 10.3 20.4 30.3 11.4 18.7 26.1 15.7 30.0 61.3 37.9 19.6 20.8 33.3 26.0 18.3 21.6 16.9 48.0 28.5 21.1 32.2 34.1 22.9 2.5 5.5 11.7 11.7 16.5 28.9 5.5 13.8 19.1 8.8 11.9 2.0 4.6 2.6 3.7 36.8 3.3 5.0 3.4 5.0 3.5 23.8 9.2 7.9 23.4 1.0 8.4 2.7 4.3 38.2 6.1 4.9 1.7 11.9 5.6 16.4 3.3 5.4 11.3 1.6 3.6 18.6 2.5 2.0 3.7 5.6 2.3 2.7 2.9 2.5 3.4 12.3 1.7 3.7 5.3 6.1 10.1 10.2 5.2 4.1 10.0 3.2 0.0 3.7 2.6 1.0 10.9 3.1 20.1 2.1 1.0 0.0 1.4 1.4 2.1 0.8 2.7 2.2 1.3 1.0 2.5 1.8 0.3 1.0 0.3 0.5 1.7 1.7 20.0 22.9 23.9 23.8 20.6 20.4 21.4 21.5 20.4 20.8 21.6 22.9 15.8 3.2 14.3 26.8 2.6 17.5 5.8 3.6 6.2 19.6 6.4 25.1 37.9 1.5 3.6 3.7 14.6 11.3 5.1 3.7 0.0 1.9 18.3 0.7 4.4 15.2 9.1 0.8 4.3 0.7 4.1 42.7 3.1 1.3 0.0 57.8 17.5 32.1 4.6 23.5 9.0 5.0 0.0 3.5 19.6 97.2 11.1 3.6 32.0 4.7 2.6 15.2 6.2 5.0 7.3 0.3 4.3 5.7 2.4 2.9 7.0 2.4 1.4 9.0 0.0 32.9 8.9 4.6 21.6 1.4 14.1 12.4 6.0 12.2 5.2 1.7 IL13RA1 "CD213a1, IL-13Ra, NR4" ENSG00000131724 "Interleukin 13 receptor subunit alpha 1" P78552 X 118727133-118794535 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 199.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 10.9;eosinophil: 12.2;myeloid DC: 17.2;neutrophil: 29.2" "Group enriched" "Detected in many" 7 "dendritic cells: 17.2;granulocytes: 29.2;monocytes: 10.9" "Cell line enhanced" "Detected in many" "HDLM-2: 181.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001587 Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 17000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Vesicles Nucleoplasm "HPA001587: AB_1079133" "unprognostic (5.14e-3)" "unprognostic (4.72e-2)" "unprognostic (7.12e-2)" "unprognostic (7.75e-2)" "unprognostic (8.81e-3)" "unprognostic (3.82e-2)" "unprognostic (1.11e-1)" "unprognostic (1.89e-1)" "unprognostic (1.51e-1)" "unprognostic (2.44e-1)" "unprognostic (1.90e-1)" "unprognostic (8.21e-2)" "prognostic unfavorable (1.19e-8)" "unprognostic (1.88e-2)" "unprognostic (2.37e-2)" "unprognostic (2.82e-2)" "unprognostic (5.08e-2)" 51.9 34.3 15.9 40.3 16.2 7.1 41.5 18.1 17.3 27.1 20.4 52.1 48.5 31.9 26.2 53.5 35.8 39.3 20.2 14.6 22.3 33.7 120.3 48.9 25.4 26.0 20.3 37.5 22.3 22.2 15.4 32.8 24.6 22.5 61.6 25.6 34.7 27.1 31.4 20.6 60.8 40.6 22.2 29.9 35.8 16.6 19.6 16.0 29.8 55.9 34.5 31.6 27.4 24.6 31.6 37.2 17.4 48.0 39.0 113.5 33.1 63.3 86.2 29.2 37.6 21.8 55.0 0.1 111.4 86.6 84.8 29.1 19.0 26.6 32.3 181.0 16.5 5.1 30.9 55.8 23.4 0.6 13.0 104.1 23.5 40.0 48.8 87.9 61.8 0.0 16.6 3.3 41.9 44.8 0.1 8.5 16.1 57.8 38.6 0.1 43.3 0.2 43.6 32.9 6.5 6.0 102.3 35.5 24.7 22.8 22.8 28.9 79.3 56.7 26.7 99.7 50.5 0.7 16.8 0.3 125.6 16.1 24.6 0.2 10.9 12.2 0.0 2.7 0.1 2.9 0.0 0.0 17.2 2.5 0.0 0.0 29.2 0.1 1.1 2.9 0.1 2.9 15.9 16.2 18.1 17.3 14.6 22.3 26.0 20.3 24.6 22.2 19.6 24.6 36.0 70.5 48.5 1.0 20.2 17.2 37.1 17.2 18.2 2.1 32.4 26.3 11.5 37.1 46.0 29.5 16.7 8.1 2.8 61.9 9.8 36.1 38.1 25.8 34.0 58.8 93.2 4.8 0.3 98.3 31.9 38.7 38.7 27.3 0.0 13.6 78.9 149.0 41.2 0.0 2.0 138.4 16.2 124.8 140.6 7.3 24.2 120.4 21.4 73.1 199.7 43.7 2.1 0.0 6.9 87.9 27.0 18.8 1.3 42.3 70.8 25.2 49.7 11.2 32.9 14.4 26.2 7.5 28.9 37.2 12.1 9.4 2.7 7.1 29.5 30.8 IL18 "IGIF, IL-18, IL-1g, IL1F4" ENSG00000150782 "Interleukin 18" Q14116 11 112143253-112164096 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 124.5;skin 1: 149.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 173.1;Basal respiratory cells: 186.4;Basal squamous epithelial cells: 215.1;Kupffer cells: 241.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 117.9;CAPAN-2: 182.3;HaCaT: 167.0;HBEC3-KT: 125.8;hTCEpi: 188.5;PC-3: 110.2;U-2 OS: 208.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003980, CAB007772" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted to blood" NA Yes 196000 16000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Golgi apparatus" Cytosol "CAB007772: AB_562304, HPA003980: AB_1851670" "unprognostic (2.31e-3)" "unprognostic (3.25e-1)" "prognostic favorable (2.78e-4)" "unprognostic (3.41e-2)" "unprognostic (1.25e-1)" "unprognostic (1.62e-1)" "unprognostic (1.65e-1)" "unprognostic (8.15e-2)" "unprognostic (3.23e-1)" "unprognostic (2.78e-1)" "unprognostic (1.96e-3)" "unprognostic (4.13e-1)" "unprognostic (3.58e-2)" "unprognostic (1.51e-1)" "unprognostic (3.19e-2)" "unprognostic (3.15e-2)" "unprognostic (9.01e-2)" 19.9 6.1 5.3 18.2 5.4 31.6 12.6 5.9 8.6 38.0 7.0 34.1 22.0 2.4 3.3 124.5 8.0 23.0 3.0 5.3 6.0 23.8 9.1 23.0 67.8 7.5 6.2 1.9 17.9 1.3 2.9 6.7 7.4 6.1 29.1 6.9 15.0 3.0 6.0 149.6 22.0 3.6 6.7 29.3 13.4 1.9 5.7 8.0 3.7 2.1 25.7 25.3 77.0 11.3 117.9 40.0 0.0 0.4 0.0 0.0 0.7 2.0 0.0 0.0 0.1 22.4 182.3 0.1 25.7 0.3 3.2 167.0 0.0 125.8 0.0 0.3 1.2 17.5 35.6 9.9 3.9 9.3 32.6 0.2 188.5 0.3 43.5 0.2 0.1 0.1 0.5 0.3 1.6 0.2 0.2 0.9 0.2 31.9 110.2 0.1 0.1 0.4 79.9 24.8 0.1 0.0 78.4 52.1 0.5 1.0 31.0 25.4 0.3 0.4 208.9 1.2 35.9 0.4 0.3 0.6 0.2 67.1 0.2 6.8 8.7 16.0 0.1 10.9 0.0 0.7 0.1 0.0 25.8 0.7 0.0 0.5 9.5 19.6 6.3 5.6 0.0 2.5 5.3 5.4 5.9 8.6 5.3 6.0 7.5 6.2 7.4 6.7 5.7 11.3 1.0 173.1 38.4 0.7 6.0 122.9 33.5 186.4 215.1 2.6 4.6 7.7 1.0 41.5 66.1 9.2 0.0 2.3 10.8 109.9 80.3 24.7 2.4 94.9 1.4 4.6 14.5 26.3 3.8 143.0 3.7 18.8 20.9 32.5 101.2 2.8 8.2 1.9 68.4 0.0 4.6 30.1 57.0 241.0 37.3 1.9 0.0 123.8 3.6 61.8 38.8 2.7 6.2 2.0 1.1 161.4 104.6 4.5 4.6 23.6 67.5 22.3 69.6 39.1 6.6 0.6 3.9 1.5 1.3 152.6 111.2 1.8 9.6 0.3 47.8 90.5 IL18R1 "CD218a, IL-1Rrp, IL1RRP" ENSG00000115604 "Interleukin 18 receptor 1" Q13478 2 102311529-102398777 "CD markers, Enzymes, Plasma proteins, Predicted membrane proteins" "Inflammatory response" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 24.2;lymphoid tissue: 18.5" "Cell type enhanced" "Detected in many" "dendritic cells: 44.7;granulocytes: 111.2;Langerhans cells: 25.4;NK-cells: 42.2;T-cells: 25.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 45.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 27.4;HHSteC: 35.4;U-937: 52.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA007615 Approved Approved Mitochondria Yes No "Cluster 48: NK-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "HPA007615: AB_1851675" "unprognostic (3.60e-3)" "unprognostic (9.75e-3)" "unprognostic (1.12e-3)" "unprognostic (3.01e-2)" "unprognostic (2.34e-3)" "unprognostic (7.11e-2)" "unprognostic (2.95e-2)" "unprognostic (1.74e-2)" "unprognostic (3.59e-1)" "unprognostic (7.86e-2)" "unprognostic (3.40e-2)" "unprognostic (1.70e-1)" "prognostic unfavorable (4.52e-4)" "unprognostic (2.62e-1)" "unprognostic (1.62e-2)" "unprognostic (5.71e-2)" "unprognostic (2.48e-2)" 8.2 2.3 1.3 5.6 1.4 2.4 5.4 1.2 1.9 4.5 1.6 4.0 4.1 3.1 1.6 2.2 3.7 2.9 4.5 1.0 2.4 4.4 6.6 24.2 4.1 1.5 1.3 1.1 1.3 3.2 1.7 6.9 1.8 3.3 1.0 0.2 2.2 5.7 0.9 2.6 8.8 0.7 1.3 18.5 4.3 0.5 2.0 2.0 2.1 1.1 2.2 4.0 2.8 1.3 1.8 0.6 0.0 0.0 1.3 0.8 2.3 0.0 1.1 0.1 0.5 0.0 0.8 0.0 0.1 0.0 3.4 0.9 0.0 2.4 0.0 27.4 1.2 2.1 0.5 0.1 35.4 8.8 10.1 7.8 1.9 3.1 5.4 0.0 7.4 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.1 1.4 1.1 0.0 0.0 0.0 0.3 0.9 0.0 0.0 1.2 0.1 0.3 0.1 0.0 0.0 0.8 0.9 0.5 3.2 0.6 0.0 0.0 0.0 0.1 52.0 3.6 10.0 0.0 4.8 6.2 0.1 16.3 0.1 3.6 4.7 3.6 0.2 0.6 1.4 6.7 45.6 0.0 10.4 4.1 1.9 1.3 1.4 1.2 1.9 1.0 2.4 1.5 1.3 1.8 1.3 2.0 1.3 10.2 0.0 8.5 0.3 2.7 0.8 1.1 1.1 0.6 0.0 0.3 0.3 3.9 0.0 2.3 1.8 0.0 0.0 44.7 0.3 1.9 0.9 0.1 1.0 4.1 7.4 0.0 3.6 0.2 0.6 1.0 3.1 5.1 1.1 111.2 0.0 10.0 7.6 0.1 0.0 1.0 0.1 0.0 2.4 25.4 0.1 0.3 16.5 3.6 12.2 1.0 0.2 42.2 1.5 0.0 1.1 0.4 0.0 10.3 1.0 0.1 0.9 3.8 0.2 6.6 0.9 1.4 0.4 1.3 0.3 1.0 0.0 25.4 0.1 0.4 0.9 IL27 "IL-27, IL-27A, IL27A, IL27p28, IL30, MGC71873, p28" ENSG00000197272 "Interleukin 27" Q8NEV9 16 28499362-28512051 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Antiviral protein, Cytokine" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "liver: 26.7" "Group enriched" "Detected in some" 5 "Hepatocytes: 18.1;Syncytiotrophoblasts: 23.1" "Cancer enriched" "Detected in some" 8 "liver cancer: 4.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.6;intermediate monocyte: 3.8" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 11 "BEWO: 17.9" "Not detected" "Not detected" "Not detected" "Not detected" CAB024722 Approved "Secreted to blood" NA NA 521000 "Cluster 7: Monocytes - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB024722: " "unprognostic (4.79e-3)" "unprognostic (2.66e-3)" "unprognostic (4.72e-2)" "unprognostic (1.52e-1)" "unprognostic (2.09e-1)" "unprognostic (6.55e-3)" "prognostic favorable (1.30e-4)" "unprognostic (3.76e-2)" "unprognostic (8.23e-3)" "unprognostic (1.29e-2)" "unprognostic (6.07e-3)" "unprognostic (4.57e-2)" "unprognostic (2.41e-7)" "unprognostic (6.44e-2)" "unprognostic (1.04e-3)" "unprognostic (2.13e-1)" "unprognostic (2.83e-2)" 0.2 0.2 0.2 1.2 0.1 0.9 0.1 0.3 0.4 0.1 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.2 0.1 26.7 0.5 0.4 0.4 0.4 0.0 0.1 0.0 0.1 0.7 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.3 1.7 0.1 0.6 0.6 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 17.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.4 3.6 0.8 0.0 3.8 0.1 0.2 0.0 0.0 0.7 0.0 0.0 0.0 2.1 1.5 0.1 0.0 0.2 1.0 0.2 0.1 0.3 0.4 0.3 0.2 0.4 0.4 0.2 0.3 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 3.1 0.0 0.0 0.1 0.0 0.0 0.0 18.1 0.9 0.0 0.4 0.0 0.0 3.5 1.2 0.1 0.0 2.3 0.0 0.0 2.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.1 0.1 0.0 0.0 0.0 IL2RG "CD132, CIDX, IMD4, SCIDX1" ENSG00000147168 "Interleukin 2 receptor subunit gamma" P31785 X 71107404-71112108 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 118.0;lymphoid tissue: 346.4" "Cell type enhanced" "Detected in many" "B-cells: 186.1;dendritic cells: 199.0;Distal enterocytes: 202.0;NK-cells: 310.0;Paneth cells: 133.2;Plasma cells: 221.2;T-cells: 289.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 6 "Karpas-707: 2316.2" "HPA046641, HPA049691" Enhanced Approved Vesicles NA NA 13000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" Vesicles "HPA046641: AB_2679733, HPA049691: AB_2680851" "unprognostic (2.97e-3)" "unprognostic (4.24e-2)" "unprognostic (1.23e-1)" "prognostic favorable (1.73e-4)" "unprognostic (8.25e-2)" "unprognostic (1.93e-3)" "unprognostic (1.37e-1)" "unprognostic (1.53e-1)" "unprognostic (1.91e-3)" "unprognostic (1.23e-2)" "unprognostic (4.36e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (2.28e-7)" "unprognostic (1.73e-1)" "unprognostic (4.69e-2)" "unprognostic (4.89e-2)" "unprognostic (9.54e-2)" 12.8 6.2 2.7 132.2 2.4 87.3 14.1 2.5 6.3 10.2 4.0 98.9 50.4 7.5 7.5 15.1 6.8 28.2 4.6 2.3 2.8 7.1 20.6 51.7 235.6 3.6 2.7 4.9 4.1 1.9 1.5 16.9 4.2 7.8 118.0 0.5 19.0 5.9 2.6 15.4 82.8 12.3 3.1 119.4 41.4 2.2 3.0 346.4 5.8 6.3 306.9 46.4 5.5 3.8 1.2 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.2 0.0 4.7 9.1 187.3 13.5 0.0 0.7 1.7 0.4 0.0 0.0 160.3 0.2 23.6 0.3 0.3 0.2 99.3 4.0 0.0 0.0 0.0 0.1 0.1 0.0 220.5 43.3 2316.2 0.0 0.0 356.4 193.7 0.4 0.9 0.1 79.5 0.8 20.0 0.0 0.7 0.2 0.3 2.3 0.1 0.5 0.0 0.0 3.5 0.4 0.0 1.0 0.0 0.5 132.1 242.2 119.6 2.1 397.4 0.9 540.5 102.2 169.7 1204.7 239.5 1179.9 604.7 1086.3 1250.7 243.5 603.0 742.0 943.1 773.0 1190.3 177.0 368.9 1422.2 1494.0 2.7 2.4 2.5 6.3 2.3 2.8 3.6 2.7 4.2 3.1 3.0 3.8 3.3 3.2 11.2 0.0 186.1 8.2 8.1 13.1 1.2 0.0 1.5 1.7 0.9 4.3 4.2 0.0 0.0 0.5 199.0 202.0 0.0 1.2 0.1 0.8 0.7 5.8 77.7 27.1 0.0 2.3 0.3 4.2 13.7 0.7 39.3 0.4 6.1 2.1 31.1 0.0 0.0 24.5 4.1 25.2 116.7 0.0 0.0 45.4 42.7 1.0 91.1 0.1 310.0 0.0 0.1 28.0 133.2 0.4 221.2 4.3 88.8 1.1 2.3 0.4 0.0 1.3 2.6 0.0 0.1 1.8 6.8 0.3 289.5 0.0 18.6 8.9 IL34 "C16orf77, IL-34, MGC34647" ENSG00000157368 "Interleukin 34" Q6ZMJ4 16 70579895-70660682 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 106.3;skin 1: 62.0" "Cell type enhanced" "Detected in many" "Leydig cells: 18.3;Peritubular cells: 40.6;Sertoli cells: 19.7;Suprabasal keratinocytes: 20.5;Theca cells: 18.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 13 "eosinophil: 18.5" "Lineage enriched" "Detected in single" 185 "granulocytes: 18.5" "Cell line enhanced" "Detected in some" "ASC TERT1: 2.1;Hep G2: 2.7;HSkMC: 2.4;NTERA-2: 5.3;U-138 MG: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 57100 "Cluster 52: Eosinophils - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 5: NTERA-2 - Transcription" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (3.76e-3)" "prognostic favorable (7.41e-4)" "unprognostic (5.70e-2)" "unprognostic (1.02e-1)" "unprognostic (2.27e-2)" "prognostic favorable (9.69e-4)" "unprognostic (8.19e-2)" "unprognostic (1.59e-3)" "unprognostic (3.83e-2)" "unprognostic (6.11e-3)" "unprognostic (3.18e-2)" "unprognostic (9.92e-2)" "prognostic unfavorable (3.52e-8)" "unprognostic (6.47e-3)" "unprognostic (4.58e-2)" "unprognostic (5.83e-2)" "unprognostic (4.37e-2)" 4.4 22.9 17.1 3.9 18.1 0.1 8.6 8.5 23.3 9.6 23.1 4.0 5.1 2.9 1.0 25.5 3.2 6.7 4.4 22.5 14.5 5.7 2.5 5.0 9.1 13.0 11.7 1.6 1.9 1.0 12.5 0.5 14.1 6.2 2.2 1.2 16.0 3.8 9.6 62.0 6.4 2.5 10.1 106.3 2.4 3.5 19.0 3.9 5.1 2.5 5.0 4.8 13.4 11.6 0.0 0.6 0.1 0.1 0.2 2.1 0.2 0.1 1.8 0.2 0.2 0.4 0.0 0.0 0.3 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.9 0.0 1.6 2.4 0.1 0.1 0.0 0.2 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 5.3 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.3 0.0 0.0 0.0 3.6 0.1 0.1 0.1 0.2 0.0 0.0 0.3 0.7 0.1 1.4 0.0 18.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 18.1 8.5 23.3 22.5 14.5 13.0 11.7 14.1 10.1 19.0 11.6 2.8 0.0 1.8 2.9 0.1 8.3 1.6 3.4 2.2 1.2 15.7 14.7 0.4 1.5 4.9 0.0 4.2 0.1 0.5 0.0 0.0 7.4 0.2 0.5 0.3 6.1 0.0 0.0 12.7 2.0 0.9 9.0 0.0 0.1 0.0 0.0 3.6 0.1 3.8 5.0 11.4 0.1 2.0 0.0 4.2 0.3 18.3 0.4 12.4 5.6 0.0 15.2 0.0 1.5 1.0 0.8 0.1 40.6 0.1 2.4 0.2 0.3 1.2 0.8 19.7 2.0 8.1 0.1 0.4 7.8 20.5 0.8 0.3 18.8 0.5 1.9 IL3RA CD123 ENSG00000185291 "Interleukin 3 receptor subunit alpha" P26951 X 1336616-1382689 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 79.0;dendritic cells: 137.5;Endothelial cells: 83.2;Langerhans cells: 47.6;monocytes: 72.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 2665.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 2665.0" "Cell line enhanced" "Detected in many" "HDLM-2: 128.8;NB-4: 24.9;RPMI-8226: 54.1" "HPA003539, CAB018374" Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "CAB018374: AB_2233620, HPA003539: AB_1078438" "prognostic favorable (9.78e-4)" "prognostic favorable (4.27e-4)" "unprognostic (8.13e-2)" "unprognostic (9.32e-2)" "unprognostic (2.09e-1)" "unprognostic (1.29e-3)" "unprognostic (1.32e-1)" "unprognostic (1.67e-1)" "unprognostic (1.38e-1)" "unprognostic (3.73e-2)" "unprognostic (5.77e-3)" "unprognostic (1.43e-1)" "unprognostic (1.50e-3)" "unprognostic (9.41e-2)" "unprognostic (2.85e-3)" "unprognostic (2.49e-1)" "unprognostic (1.46e-1)" 25.2 2.9 7.1 15.8 13.6 25.0 20.6 16.1 11.7 6.4 0.2 8.1 5.5 8.7 1.6 5.4 8.0 11.3 13.0 5.9 8.1 9.2 1.8 25.0 25.1 11.7 10.6 8.8 5.4 3.4 2.8 6.2 11.1 7.0 6.6 22.0 9.5 3.2 12.1 12.7 9.2 12.3 7.5 11.1 6.9 3.5 10.1 4.4 10.3 8.6 13.0 12.4 6.3 20.5 0.2 9.4 3.6 1.3 0.1 0.0 1.1 1.2 0.3 0.0 0.1 0.9 1.5 1.2 7.2 0.2 0.6 9.6 0.0 0.0 0.0 128.8 3.9 0.6 2.1 0.4 0.0 0.8 15.6 0.0 0.0 0.0 0.0 4.1 8.2 0.9 0.3 6.1 0.0 1.4 0.7 24.9 3.1 0.8 0.5 1.4 4.2 54.1 0.0 1.4 0.6 0.4 0.6 0.3 2.8 1.8 1.2 17.8 0.4 0.5 1.5 0.5 0.3 12.5 3.9 1.1 9.8 2.8 0.1 2665.0 5.6 83.9 0.6 31.7 1.0 2.5 0.9 0.5 14.9 8.9 0.7 0.7 4.6 14.2 42.5 628.5 0.5 12.0 7.1 13.6 16.1 11.7 5.9 8.1 11.7 10.6 11.1 7.5 10.1 20.5 79.0 3.2 1.8 11.8 6.8 5.9 0.7 0.9 1.2 2.3 0.5 0.9 2.2 1.5 1.0 0.0 10.4 0.1 137.5 4.7 0.0 0.4 0.2 2.7 1.4 83.2 0.0 3.0 7.3 0.2 0.1 4.3 0.5 1.5 11.4 0.4 24.3 0.7 4.6 0.0 14.3 7.3 0.0 2.8 47.6 0.1 0.3 32.9 8.8 13.1 72.6 0.6 1.0 6.0 18.2 0.1 3.4 0.7 4.0 0.7 0.2 0.0 0.4 3.2 0.0 3.6 3.2 0.1 0.7 0.7 5.5 0.3 1.6 1.3 0.6 2.1 INPP4B ENSG00000109452 "Inositol polyphosphate-4-phosphatase type II B" O15327 4 142023160-142847432 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 158.7;Early spermatids: 178.1;Excitatory neurons: 196.8;Inhibitory neurons: 614.4;Late spermatids: 291.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 30.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 150.4;SK-MEL-30: 66.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037681, HPA037682" Approved Approved Centrosome NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 23: Testis - Cell cycle regulation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Centrosome "HPA037681: AB_10670389, HPA037682: AB_10671377" "unprognostic (9.79e-2)" "unprognostic (1.11e-1)" "unprognostic (1.95e-1)" "unprognostic (9.25e-2)" "unprognostic (1.77e-1)" "unprognostic (8.24e-2)" "unprognostic (3.03e-3)" "unprognostic (5.76e-3)" "unprognostic (1.95e-2)" "unprognostic (3.16e-1)" "prognostic unfavorable (1.03e-4)" "unprognostic (8.58e-2)" "unprognostic (1.26e-2)" "unprognostic (2.79e-2)" "unprognostic (1.30e-1)" "unprognostic (4.58e-1)" "unprognostic (1.39e-2)" 9.9 4.0 5.2 6.7 6.7 2.1 18.3 3.2 6.4 13.1 0.3 5.8 4.6 5.4 3.9 7.5 7.3 7.9 17.4 5.5 3.4 5.4 1.8 6.5 10.8 1.3 2.7 5.7 2.5 2.0 1.3 5.7 1.9 4.7 5.1 1.7 2.7 4.7 7.9 3.6 5.5 7.3 0.0 6.8 5.8 18.6 7.3 5.9 4.3 5.2 6.9 14.0 8.7 6.0 27.7 11.4 7.3 3.6 5.5 3.4 1.4 32.5 37.9 8.2 15.3 3.1 150.4 0.8 8.9 29.4 12.6 41.1 0.0 37.9 19.1 0.1 1.1 6.6 4.0 0.1 1.8 1.4 5.0 5.9 5.2 5.8 19.4 24.7 4.8 0.0 0.0 1.5 17.9 49.1 1.1 0.0 0.3 16.8 8.1 0.3 24.7 1.4 11.3 50.3 0.6 0.7 3.7 11.2 66.6 4.3 34.2 4.9 3.1 18.8 22.6 28.0 0.3 0.4 0.1 0.1 4.4 29.7 49.5 6.1 0.2 0.0 5.2 0.0 10.1 0.0 30.4 13.6 0.1 0.1 20.6 8.9 0.5 17.0 0.0 0.1 17.4 5.9 5.2 6.7 3.2 6.4 5.5 3.4 1.3 2.7 1.9 0.0 7.3 6.0 13.4 0.0 0.6 158.7 2.6 6.6 9.5 7.0 4.0 7.5 49.0 15.5 42.2 7.2 20.2 9.2 0.0 1.7 8.7 8.7 5.9 12.2 178.1 19.8 58.2 13.2 8.9 6.1 196.8 30.6 5.1 5.1 19.4 5.4 6.3 0.6 6.4 0.3 8.1 6.7 614.4 3.5 4.1 2.8 4.9 291.9 13.7 3.9 72.9 47.8 1.3 0.9 2.1 79.4 57.6 76.3 0.2 6.4 4.5 20.5 10.1 0.9 35.7 0.8 85.5 5.2 84.7 2.5 1.9 1.9 2.6 1.9 60.4 1.8 4.3 42.9 INS-IGF2 ENSG00000129965 "INS-IGF2 readthrough" F8WCM5 11 2132538-2161209 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 48 "pancreas: 9.1" "Cell type enriched" "Detected in single" 11 "Hepatocytes: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB019430 Enhanced "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 2: Hepatocytes - Metabolism" "CAB019430: AB_10691857" "unprognostic (1.33e-1)" "unprognostic (2.34e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ITCH AIP4 ENSG00000078747 "Itchy E3 ubiquitin protein ligase" Q96J02 20 34363241-34540748 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Apoptosis, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 139.7;Oligodendrocytes: 260.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021126, HPA049032, CAB072824, CAB072825" Supported Enhanced Nucleoplasm,Vesicles No No "Cluster 1: Neutrophils - Mixed function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm Vesicles "CAB072824: , CAB072825: , HPA021126: AB_1851941, HPA049032: AB_2680607" "unprognostic (2.51e-1)" "unprognostic (6.95e-2)" "unprognostic (1.25e-3)" "unprognostic (3.22e-2)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (2.78e-1)" "unprognostic (9.29e-3)" "unprognostic (1.94e-1)" "unprognostic (3.89e-3)" "unprognostic (1.28e-3)" "unprognostic (1.42e-1)" "unprognostic (1.84e-2)" "unprognostic (1.30e-1)" "unprognostic (2.24e-1)" "unprognostic (3.23e-2)" "unprognostic (2.21e-1)" 19.5 16.2 13.7 18.1 27.1 27.3 20.0 19.6 17.7 24.5 17.7 21.6 20.2 19.4 16.6 42.8 15.7 17.0 20.2 14.7 15.9 23.3 55.6 18.7 21.4 19.8 20.0 18.8 16.5 23.1 7.8 25.6 21.0 19.6 23.5 25.6 18.7 19.9 17.2 14.0 20.9 21.5 15.9 20.4 20.9 38.5 20.2 23.2 26.3 21.7 25.7 30.6 14.8 45.7 55.5 34.6 35.2 25.9 38.3 57.4 42.7 43.5 52.0 56.2 54.0 101.5 83.8 26.7 42.1 55.6 73.9 66.2 54.9 92.3 66.2 20.8 17.9 78.3 28.2 59.3 43.9 32.6 34.4 31.7 46.2 44.4 72.2 49.8 41.7 40.6 45.5 45.7 46.2 26.5 49.2 18.8 16.9 35.6 44.2 40.9 76.3 63.6 34.7 91.2 21.4 16.4 82.0 32.7 51.0 33.9 38.3 31.1 39.5 61.5 36.0 42.8 33.3 36.2 40.5 40.0 41.0 21.6 38.0 4.6 6.7 7.0 12.0 7.0 12.5 9.2 4.2 6.1 4.9 7.8 3.7 5.7 20.2 7.6 4.9 14.3 5.8 4.3 13.7 27.1 19.6 17.7 14.7 15.9 19.8 20.0 21.0 15.9 20.2 45.7 26.1 12.8 21.8 56.5 33.1 15.0 23.9 11.7 25.6 19.5 15.1 8.5 25.0 12.8 25.6 31.3 25.0 17.5 46.1 28.8 5.9 12.8 59.0 26.5 34.6 20.7 12.0 26.5 85.0 16.3 21.2 24.2 33.1 36.1 19.0 17.9 18.2 53.0 15.8 15.2 72.3 16.9 10.2 24.3 26.7 139.7 22.4 31.4 26.6 68.4 30.0 38.2 43.3 79.4 260.0 22.6 23.7 15.4 50.3 25.8 21.1 26.8 23.5 26.0 13.1 21.4 22.0 40.6 25.5 30.4 16.2 46.9 30.8 12.3 11.9 40.6 ITFG1 "CDA08, LNKN-1, TIP" ENSG00000129636 "Integrin alpha FG-GAP repeat containing 1" Q8TB96 16 47154387-47464149 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 285.9;Oligodendrocytes: 263.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015590, HPA019728" Approved Approved "Intermediate filaments,Aggresome" "Intracellular and membrane" NA NA 28000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Intermediate filaments" Aggresome "HPA015590: AB_1846347, HPA019728: AB_1846348" "unprognostic (6.53e-3)" "unprognostic (9.26e-3)" "unprognostic (3.13e-2)" "unprognostic (1.35e-1)" "unprognostic (1.27e-1)" "unprognostic (1.39e-3)" "unprognostic (3.70e-2)" "unprognostic (9.32e-2)" "unprognostic (2.47e-1)" "unprognostic (2.11e-1)" "unprognostic (1.62e-1)" "unprognostic (9.54e-2)" "prognostic favorable (1.95e-8)" "unprognostic (1.56e-2)" "unprognostic (1.61e-1)" "unprognostic (3.28e-2)" "unprognostic (4.62e-3)" 25.3 42.2 18.5 16.4 23.8 12.5 25.2 17.1 22.0 28.8 26.0 35.1 30.5 27.8 31.2 19.1 26.3 28.8 44.7 23.7 22.9 47.8 45.4 27.4 13.5 13.6 14.0 28.0 27.3 56.0 15.7 40.7 15.9 29.4 33.1 33.3 21.8 28.9 23.8 12.9 26.7 29.1 16.6 19.3 28.3 36.7 18.5 17.2 43.2 24.6 16.7 24.4 13.8 19.5 22.2 24.8 44.0 31.1 84.1 65.0 54.1 50.7 72.9 45.6 24.3 14.2 51.8 25.9 70.4 63.5 30.9 31.9 21.6 33.0 44.9 11.8 17.0 14.0 22.0 33.2 39.4 32.7 59.6 48.3 55.6 23.3 30.1 96.3 44.4 24.2 40.3 33.5 58.3 21.1 20.2 16.3 14.5 27.4 24.5 31.0 43.4 66.5 60.2 15.9 21.9 30.8 46.0 53.6 24.0 43.7 23.7 29.9 43.0 48.9 23.7 26.3 20.7 47.6 66.7 48.4 48.9 20.6 39.2 17.9 33.9 33.4 16.0 33.0 15.2 16.6 19.0 17.7 25.8 17.2 20.7 17.4 21.2 23.8 33.1 17.5 26.1 29.2 18.5 23.8 17.1 22.0 23.7 22.9 13.6 14.0 15.9 16.6 18.5 19.5 38.9 51.3 28.1 165.9 37.2 38.4 43.4 81.3 27.9 50.8 32.6 23.2 56.8 50.1 62.2 82.8 47.9 100.6 32.3 79.3 9.8 60.5 129.0 33.0 28.7 37.8 61.9 27.8 250.7 52.4 86.4 48.5 41.8 35.0 8.2 54.5 39.3 68.7 50.9 40.4 285.9 43.2 73.2 53.8 30.0 32.0 35.1 41.9 28.4 146.1 45.4 39.4 38.1 214.6 263.5 45.3 37.0 61.3 60.1 35.3 65.2 49.6 54.5 47.4 78.9 30.1 49.8 93.7 98.3 25.5 30.3 114.0 29.9 66.0 38.1 37.4 ITGA5 "CD49e, FNRA" ENSG00000161638 "Integrin subunit alpha 5" P08648 12 54395261-54419266 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 398.8;smooth muscle: 361.9;urinary bladder: 386.5" "Cell type enhanced" "Detected in many" "Endothelial cells: 101.5;Extravillous trophoblasts: 391.9;Hepatic stellate cells: 88.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 89.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 615.4;HUVEC TERT2: 1360.8;TIME: 1277.7;U-87 MG: 623.6" "Region enriched" "Detected in many" 5 "basal ganglia: 10.4" "Low region specificity" "Detected in many" "HPA002642, CAB009008" Enhanced NA NA 26000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB009008: AB_647474, HPA002642: AB_1078469" "unprognostic (7.51e-3)" "prognostic unfavorable (4.07e-6)" "prognostic unfavorable (8.43e-4)" "unprognostic (1.58e-1)" "unprognostic (8.51e-3)" "prognostic unfavorable (2.91e-4)" "prognostic unfavorable (2.23e-5)" "prognostic unfavorable (2.44e-4)" "unprognostic (2.76e-2)" "unprognostic (6.19e-2)" "unprognostic (8.99e-2)" "unprognostic (8.28e-2)" "prognostic unfavorable (1.32e-8)" "unprognostic (2.11e-3)" "unprognostic (3.35e-2)" "prognostic unfavorable (8.89e-4)" "unprognostic (2.18e-3)" 114.4 47.1 8.7 136.2 9.2 46.4 69.1 9.2 13.8 64.0 9.7 398.8 15.3 106.1 5.0 72.3 71.1 50.8 113.9 8.5 9.0 26.6 48.6 121.7 17.5 11.3 9.9 39.3 20.9 14.9 10.5 91.6 11.3 141.9 40.6 1.3 24.5 114.9 29.1 50.5 87.6 361.9 10.6 16.3 90.8 4.0 17.1 13.2 40.5 25.7 12.5 386.5 76.9 9.8 65.4 23.9 43.6 0.6 130.8 278.7 113.5 286.0 308.2 300.9 220.6 17.1 15.3 0.5 206.9 308.5 149.1 10.1 12.5 81.4 197.4 0.4 12.2 28.1 31.3 1.1 179.5 88.7 44.4 206.8 39.2 351.9 258.3 615.4 1360.8 15.6 25.6 0.8 165.4 6.4 13.7 99.2 18.1 4.2 19.1 13.7 29.2 6.2 46.9 1.1 0.1 0.6 57.7 4.3 2.2 93.8 7.1 79.9 1277.7 353.0 62.3 85.9 121.5 0.3 3.6 0.7 623.6 83.0 118.5 16.4 64.9 0.5 14.2 27.3 11.2 0.1 10.9 10.9 62.6 0.3 7.7 6.6 89.1 26.4 24.0 3.4 4.9 42.9 8.7 9.2 9.2 13.8 8.5 9.0 11.3 9.9 11.3 10.6 17.1 9.8 58.3 3.2 4.4 1.6 2.7 14.3 3.4 11.3 4.0 1.1 6.1 2.8 16.3 14.3 4.9 0.0 0.0 5.4 19.6 0.0 0.0 34.0 0.3 1.7 32.1 101.5 0.0 3.4 1.4 3.4 391.9 45.0 0.5 3.0 19.7 5.1 88.9 27.1 28.4 0.0 1.2 0.0 2.0 22.8 58.5 0.5 6.5 38.5 10.6 14.0 24.6 0.0 21.6 0.0 0.2 8.8 0.0 4.5 8.7 3.6 0.0 0.2 1.8 1.1 13.1 11.1 30.7 0.2 0.7 1.3 10.7 34.6 14.3 2.4 0.0 2.0 ITGAL "CD11A, LFA-1" ENSG00000005844 "Integrin subunit alpha L" P20701 16 30472658-30523567 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction, Phagocytosis" "Integrin, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.8;lymphoid tissue: 64.9" "Cell type enhanced" "Detected in many" "dendritic cells: 118.6;monocytes: 36.8;NK-cells: 152.4;Plasma cells: 46.6;T-cells: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 121.7" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 5 "HMC-1: 608.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB025011 Enhanced NA NA 1600000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB025011: " "unprognostic (1.10e-2)" "unprognostic (4.26e-3)" "unprognostic (3.72e-3)" "prognostic favorable (5.63e-5)" "unprognostic (2.88e-1)" "prognostic favorable (3.34e-4)" "unprognostic (1.63e-1)" "unprognostic (5.69e-3)" "prognostic favorable (5.57e-4)" "unprognostic (3.37e-2)" "unprognostic (4.98e-2)" "unprognostic (1.84e-1)" "prognostic unfavorable (2.69e-5)" "unprognostic (2.89e-1)" "unprognostic (3.05e-2)" "unprognostic (1.39e-1)" "unprognostic (1.71e-2)" 4.2 1.4 0.3 36.7 0.5 36.8 2.3 0.3 1.0 2.4 0.5 5.5 6.0 2.3 1.0 2.5 3.0 7.0 1.4 0.3 0.4 2.6 10.6 22.0 62.4 1.6 1.1 1.3 1.0 0.5 1.2 3.0 1.4 2.4 8.6 0.0 5.3 1.4 0.9 1.4 19.7 3.6 0.7 64.9 8.6 1.0 1.6 55.2 3.5 0.9 46.4 6.9 2.3 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.0 1.7 0.0 0.1 0.0 1.1 608.0 0.0 0.0 0.1 0.0 0.0 0.0 5.6 0.0 134.3 0.0 0.0 43.3 3.5 0.0 0.0 0.0 0.1 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.4 26.0 0.0 0.0 0.0 0.0 0.0 36.6 12.5 0.0 0.1 3.8 0.0 5.3 24.4 17.0 56.6 48.0 27.7 4.8 21.4 42.7 22.3 1.7 9.4 29.7 14.3 24.2 121.7 6.0 15.6 43.6 0.3 0.5 0.3 1.0 0.3 0.4 1.6 1.1 1.4 0.7 1.6 2.1 1.2 6.4 10.5 0.7 19.1 0.8 0.3 0.0 0.0 0.4 1.2 1.0 1.9 0.0 1.9 1.8 0.0 0.2 118.6 0.3 0.0 0.1 0.5 4.1 0.6 2.3 0.0 4.8 3.6 0.0 0.6 1.4 1.1 0.9 5.1 0.1 5.3 4.9 19.3 0.0 2.8 0.2 0.0 30.0 3.4 0.7 0.0 31.5 1.8 15.9 36.8 0.1 152.4 0.5 1.6 0.0 0.0 0.0 46.6 0.1 0.9 0.3 6.7 0.9 0.0 1.2 0.7 0.2 0.2 0.1 0.3 0.7 84.9 0.1 0.0 0.2 ITGAX CD11C ENSG00000140678 "Integrin subunit alpha X" P20702 16 31355134-31382999 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 48.1;brain: 33.7;lung: 58.1;lymphoid tissue: 67.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 51.1;granulocytes: 74.0;Hofbauer cells: 45.1;Kupffer cells: 51.5;Langerhans cells: 77.3;Macrophages: 141.7;Microglial cells: 56.2;NK-cells: 68.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 87.5" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 6 "HMC-1: 106.1" "Not detected" "Not detected" "CAB004458, HPA004723, CAB072871" Enhanced NA NA 50000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "CAB004458: AB_626859, CAB072871: AB_2665723, HPA004723: AB_1846231" "unprognostic (9.75e-3)" "unprognostic (2.49e-2)" "unprognostic (1.75e-1)" "unprognostic (1.99e-2)" "unprognostic (1.89e-1)" "unprognostic (2.29e-2)" "unprognostic (1.27e-1)" "unprognostic (9.59e-2)" "unprognostic (8.06e-3)" "unprognostic (3.20e-1)" "unprognostic (7.75e-2)" "unprognostic (3.34e-1)" "prognostic unfavorable (1.37e-4)" "unprognostic (3.92e-2)" "unprognostic (3.04e-2)" "unprognostic (2.82e-1)" "unprognostic (2.95e-2)" 12.9 2.3 6.0 42.7 8.1 48.1 4.3 8.8 33.7 2.2 8.4 2.9 2.3 2.8 0.8 2.0 5.9 10.8 3.5 6.2 9.3 2.9 6.3 58.1 23.2 14.6 11.8 1.0 2.9 1.4 2.9 4.6 14.3 3.2 4.3 0.6 4.5 1.5 1.3 2.1 5.5 4.7 13.0 67.5 4.8 0.6 18.4 4.0 2.8 3.2 12.3 9.2 2.1 24.8 0.1 0.6 0.1 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.4 0.0 9.0 0.0 0.3 0.1 0.0 0.3 0.1 18.6 0.1 0.1 0.3 0.4 0.0 1.1 106.1 0.1 0.1 1.7 0.2 0.7 1.0 0.0 0.1 0.4 0.0 0.0 0.1 8.8 0.4 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 2.7 0.1 0.0 3.3 0.8 0.0 1.6 0.0 0.1 0.1 0.0 0.2 4.9 1.8 0.3 12.8 29.1 27.1 4.8 50.3 0.4 2.1 0.1 0.7 34.7 1.0 0.1 0.7 87.5 41.4 61.0 0.6 0.1 11.5 6.0 8.1 8.8 33.7 6.2 9.3 14.6 11.8 14.3 13.0 18.4 24.8 0.8 12.8 51.1 0.0 9.8 2.8 0.3 0.0 0.0 0.1 0.6 1.3 1.5 0.0 10.5 0.0 0.0 0.4 33.6 0.0 0.0 0.3 0.0 0.4 0.5 4.8 0.0 3.4 0.2 0.0 0.6 4.4 0.0 0.5 74.0 0.0 1.1 0.1 45.1 0.0 0.3 0.0 0.0 51.5 77.3 0.0 0.0 141.7 1.8 56.2 35.3 0.1 68.0 0.5 0.3 0.2 0.0 0.0 5.5 0.2 0.0 0.3 1.5 0.1 0.0 0.6 1.0 0.0 0.2 0.0 1.1 0.4 16.5 0.1 0.0 0.1 ITGB2 "CD18, LFA-1, MAC-1, MFI7" ENSG00000160255 "Integrin subunit beta 2" P05107 21 44885953-44931989 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 376.2;lymphoid tissue: 175.2" "Group enriched" "Detected in many" 6 "dendritic cells: 417.6;Hofbauer cells: 652.4;Kupffer cells: 485.9;Langerhans cells: 259.1;Macrophages: 527.4;monocytes: 463.8;NK-cells: 959.9;T-cells: 254.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "THP-1: 812.4;U-937: 615.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008877, HPA016894" Enhanced Supported "Plasma membrane,Rods & Rings" NA NA 3300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Rods & Rings" "HPA008877: AB_1846256, HPA016894: AB_1846257" "unprognostic (1.94e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (6.21e-3)" "unprognostic (2.95e-2)" "unprognostic (9.73e-3)" "unprognostic (2.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.18e-2)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.87e-3)" "unprognostic (1.42e-1)" "unprognostic (4.42e-2)" "unprognostic (2.65e-2)" "unprognostic (4.83e-2)" 54.5 23.2 8.2 175.2 9.5 376.2 15.4 13.1 9.3 15.5 11.7 25.2 23.8 8.5 2.8 16.2 17.0 36.4 11.8 7.7 14.2 8.4 23.4 78.0 169.1 29.5 19.9 7.2 11.3 5.1 4.6 44.4 28.1 8.8 13.9 1.1 19.5 9.2 6.8 9.3 32.8 46.4 23.9 137.2 29.1 5.9 26.2 87.2 7.3 7.6 68.4 46.3 5.9 50.4 1.9 4.8 0.0 0.0 0.0 0.3 1.7 0.0 2.7 0.1 0.0 0.4 0.4 17.9 128.1 0.2 0.6 0.5 0.0 0.2 0.0 1.5 1.4 18.2 0.0 3.2 0.1 106.6 27.5 1.6 0.1 0.5 0.3 0.1 0.3 58.0 0.7 1.4 7.0 4.0 117.8 126.1 0.4 0.4 2.4 1.5 23.2 64.6 4.7 0.0 0.6 1.3 3.4 2.5 1.7 0.0 0.4 812.4 2.5 0.2 6.6 0.4 3.7 0.8 5.9 2.9 0.1 615.0 0.9 186.6 1848.8 1224.1 726.7 1144.9 326.6 86.1 349.7 506.5 1031.4 115.2 233.1 396.5 1386.1 585.5 1183.5 165.5 288.0 3034.2 8.2 9.5 13.1 9.3 7.7 14.2 29.5 19.9 28.1 23.9 26.2 50.4 7.1 16.0 29.6 0.3 81.7 5.5 0.5 9.6 0.6 0.0 4.1 6.5 4.0 14.3 18.6 5.5 0.0 4.0 417.6 0.3 0.0 3.4 1.0 0.6 0.5 16.8 0.0 19.6 0.5 0.4 4.8 5.3 2.6 0.7 24.1 8.2 9.7 8.6 652.4 0.0 0.3 0.2 2.0 485.9 259.1 2.8 0.6 527.4 5.4 27.2 463.8 0.4 959.9 0.0 0.2 0.6 0.1 1.5 50.5 0.6 1.8 4.2 3.6 0.8 6.6 2.1 3.2 0.2 1.0 0.9 5.1 5.6 254.5 0.0 0.3 0.7 ITGB3 "CD61, GP3A, GPIIIa" ENSG00000259207 "Integrin subunit beta 3" P05106 17 47253827-47313743 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 51.4" "Cell type enhanced" "Detected in some" "Early spermatids: 3.9;Late spermatids: 8.8;Macrophages: 15.8;Proximal tubular cells: 4.6;Sertoli cells: 6.6" "Group enriched" "Detected in many" 6 "melanoma: 7.5;renal cancer: 3.6;thyroid cancer: 11.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 19 "basophil: 5.4;neutrophil: 2.5" "Lineage enriched" "Detected in single" 26 "granulocytes: 5.4" "Cell line enhanced" "Detected in many" "EFO-21: 167.8;HEL: 163.4;RPTEC TERT1: 109.8;U-87 MG: 78.3;WM-115: 255.9" HPA027852 Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA 38000000 "Cluster 34: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" Nucleoplasm "HPA027852: AB_10601760" "unprognostic (1.13e-2)" "unprognostic (1.97e-3)" "unprognostic (2.47e-1)" "unprognostic (3.00e-2)" "unprognostic (1.91e-2)" "unprognostic (6.04e-3)" "unprognostic (3.70e-1)" "unprognostic (3.00e-1)" "unprognostic (1.44e-1)" "unprognostic (3.85e-1)" "unprognostic (6.35e-2)" "unprognostic (7.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.03e-2)" "unprognostic (2.72e-2)" "unprognostic (1.48e-1)" "unprognostic (1.17e-3)" 8.0 0.6 0.3 9.5 0.7 6.2 5.3 0.7 1.0 3.8 1.0 16.9 3.5 13.2 2.6 4.2 7.6 3.5 5.5 0.5 0.8 15.0 3.4 5.6 0.9 2.3 1.0 1.5 0.7 1.2 1.2 4.5 2.0 4.8 7.0 0.9 2.6 16.1 1.5 2.7 5.8 22.9 1.2 2.9 3.8 2.5 1.2 0.3 51.4 2.4 1.2 9.6 2.6 1.1 0.1 1.5 0.7 0.1 8.6 3.8 0.1 4.7 23.1 9.6 8.6 0.3 0.1 0.6 167.8 1.2 13.4 0.0 0.1 0.0 12.6 3.4 0.0 163.4 0.5 0.0 7.8 0.0 0.2 3.4 0.0 54.6 1.4 6.7 43.6 2.5 0.5 0.3 2.1 0.0 1.0 0.1 0.1 0.0 0.8 0.0 4.2 0.0 109.8 0.2 0.0 0.5 5.6 0.0 33.2 8.8 0.1 0.2 47.1 2.1 2.4 1.3 11.7 0.2 0.1 1.1 78.3 0.0 255.9 5.4 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.1 0.1 0.1 0.0 6.8 0.3 0.7 0.7 1.0 0.5 0.8 2.3 1.0 2.0 1.2 1.2 1.1 1.3 0.0 0.0 0.0 0.5 0.1 0.2 0.9 0.0 0.0 0.1 0.3 0.8 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 3.9 0.8 0.9 3.1 0.0 0.0 0.4 0.4 0.0 2.1 0.0 0.9 0.0 0.6 1.8 0.7 0.8 0.0 0.6 0.0 0.0 0.3 0.7 8.8 0.3 15.8 0.0 1.0 0.4 0.0 0.0 0.0 0.4 1.5 0.0 1.2 0.0 0.3 0.0 4.6 0.2 0.0 6.6 0.3 2.1 0.0 2.0 0.1 0.4 1.2 0.3 0.4 0.0 0.2 ITGB8 ENSG00000105855 "Integrin subunit beta 8" P26012 7 20330702-20415754 "Cancer-related genes, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.9;choroid plexus: 39.4" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 376.2;Glandular and luminal cells: 551.9;Oligodendrocyte precursor cells: 192.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 133 "basophil: 16.5" "Lineage enriched" "Detected in single" 133 "granulocytes: 16.5" "Cell line enhanced" "Detected in many" "AF22: 44.3;EFO-21: 54.6;RPTEC TERT1: 88.1;WM-115: 127.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027796, HPA027797" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "HPA027796: AB_10600299, HPA027797: AB_10600879" "unprognostic (8.32e-3)" "unprognostic (1.42e-1)" "unprognostic (1.03e-1)" "unprognostic (3.37e-3)" "unprognostic (5.63e-2)" "unprognostic (3.53e-1)" "unprognostic (1.75e-1)" "unprognostic (1.46e-1)" "unprognostic (4.36e-2)" "unprognostic (1.75e-2)" "unprognostic (2.49e-3)" "unprognostic (8.47e-2)" "prognostic favorable (1.77e-4)" "unprognostic (2.90e-1)" "unprognostic (1.56e-1)" "unprognostic (4.63e-2)" "unprognostic (6.92e-3)" 3.8 2.6 25.7 4.2 41.8 0.3 9.6 53.9 19.2 15.4 39.4 3.7 3.2 7.7 14.0 6.4 7.5 8.7 2.9 19.5 37.5 21.6 0.8 2.4 0.5 38.9 48.4 4.7 13.3 5.1 5.4 5.2 42.7 6.7 2.8 4.6 13.6 9.0 0.2 6.3 4.2 3.0 39.7 0.0 4.2 6.5 35.6 0.8 2.1 0.9 6.9 7.2 9.0 48.6 28.2 1.1 44.3 5.6 3.7 15.2 0.0 0.1 0.5 0.2 1.5 0.3 6.9 0.0 54.6 2.0 1.7 30.1 1.9 4.5 0.5 0.0 0.7 0.0 23.1 0.0 1.8 0.0 0.1 1.8 12.6 0.5 2.4 27.1 2.4 0.0 0.0 8.3 0.8 0.1 0.0 0.0 3.3 0.4 4.8 0.0 3.7 0.0 88.1 2.5 0.7 1.9 8.6 0.2 23.5 0.8 0.7 0.1 3.0 11.2 7.1 3.2 5.8 10.2 0.1 0.0 2.7 0.0 127.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 25.7 41.8 53.9 19.2 19.5 37.5 38.9 48.4 42.7 39.7 35.6 48.6 0.7 12.8 4.8 106.4 2.5 33.1 117.2 39.4 34.7 13.3 26.3 18.7 3.0 38.6 57.9 38.6 0.0 20.0 0.4 5.0 7.9 26.3 3.0 376.2 150.6 5.2 34.0 0.0 28.1 17.4 1.2 15.5 7.7 551.9 1.3 0.9 1.4 0.2 3.3 1.7 8.2 7.4 34.6 1.0 4.7 6.5 44.1 9.8 3.6 4.7 31.6 24.3 0.0 192.0 119.2 35.8 6.1 44.8 2.0 149.7 14.5 76.7 100.1 1.4 0.0 4.8 7.0 1.4 1.1 34.6 12.4 4.9 5.5 1.9 9.6 150.7 ITIH2 H2P ENSG00000151655 "Inter-alpha-trypsin inhibitor heavy chain 2" P19823 10 7703316-7749520 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 668 "liver: 2156.1" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 489.6" "Cancer enriched" "Detected in many" 279 "liver cancer: 626.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 453 "Hep G2: 1103.0" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA059150 Supported Approved "Golgi apparatus" "Secreted to blood" NA NA 32000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Golgi apparatus" "HPA059150: AB_2683930" "unprognostic (4.82e-2)" "unprognostic (6.10e-2)" "unprognostic (2.48e-2)" "unprognostic (1.21e-2)" "unprognostic (2.01e-2)" "unprognostic (2.55e-3)" "prognostic favorable (1.48e-4)" "unprognostic (1.37e-1)" "unprognostic (1.79e-1)" "unprognostic (1.47e-2)" "unprognostic (2.28e-1)" "unprognostic (2.02e-1)" "unprognostic (2.10e-8)" "unprognostic (9.91e-3)" "unprognostic (1.70e-1)" "unprognostic (2.35e-1)" "unprognostic (4.46e-4)" 0.1 0.2 0.3 0.1 1.1 0.1 3.0 1.6 3.2 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.2 0.3 0.1 0.6 1.0 0.8 2156.1 0.6 0.1 0.6 0.5 0.0 0.2 0.0 1.7 0.1 0.6 0.0 0.0 0.3 0.0 0.0 0.8 0.4 0.0 0.0 0.9 0.3 0.5 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.6 1103.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 2.4 0.0 0.1 0.7 0.0 0.4 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 1.1 1.6 3.2 0.6 1.0 0.6 0.5 0.6 0.9 0.9 0.7 0.1 0.0 2.2 0.7 1.0 0.0 0.0 0.0 0.0 0.0 2.8 0.3 0.4 117.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 4.1 0.0 0.0 0.6 0.0 2.7 3.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 8.2 489.6 0.1 0.0 1.4 0.0 0.0 9.4 0.0 2.1 0.0 0.0 0.0 18.7 0.0 0.0 0.0 1.5 1.8 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.5 0.0 0.0 0.0 ITIH4 "H4P, IHRP, ITIHL1" ENSG00000055955 "Inter-alpha-trypsin inhibitor heavy chain 4" Q14624 3 52812962-52830688 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 38 "liver: 1863.4" "Group enriched" "Detected in many" 5 "Early spermatids: 119.2;Hepatocytes: 134.6;Late spermatids: 126.5" "Cancer enriched" "Detected in single" 27 "liver cancer: 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 2.4;JURKAT: 2.0;U-266/70: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001835, HPA003948, CAB072872" Enhanced Approved Vesicles "Secreted to blood" NA NA 3060000 58000000000 "Cluster 15: NK-cells - Transcription" "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB072872: AB_2665724, HPA001835: AB_1079432, HPA003948: AB_1079433" "unprognostic (6.08e-2)" "unprognostic (4.45e-2)" "unprognostic (1.67e-1)" "unprognostic (2.69e-1)" "unprognostic (2.64e-1)" "unprognostic (1.96e-1)" "unprognostic (5.86e-2)" "unprognostic (1.98e-2)" "unprognostic (5.64e-2)" "unprognostic (1.02e-1)" "unprognostic (2.47e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-14)" "unprognostic (1.71e-3)" "unprognostic (2.96e-2)" "unprognostic (1.52e-1)" "unprognostic (4.21e-5)" 4.2 18.5 4.1 1.2 4.2 10.0 3.0 3.7 5.0 4.2 3.5 3.6 1.0 2.9 1.7 1.4 3.8 1.1 3.2 3.9 3.6 5.4 1863.4 4.9 1.7 3.9 3.8 2.4 48.9 0.1 4.3 0.7 3.9 4.0 1.0 3.3 2.1 1.8 40.3 2.5 3.4 1.5 3.6 7.4 3.9 1.8 3.8 2.2 5.2 2.8 1.2 5.3 3.3 3.9 0.0 0.1 0.4 0.9 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.2 0.1 0.4 0.0 0.0 0.2 2.4 0.1 1.0 0.0 1.2 0.4 1.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 2.0 0.3 0.8 0.0 0.1 0.2 0.3 0.4 0.1 0.0 0.8 0.3 0.0 0.2 0.3 0.0 0.4 0.3 0.0 0.1 0.4 0.5 0.3 0.1 0.0 0.4 0.4 0.0 3.0 1.4 0.2 0.0 0.3 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 4.1 4.2 3.7 5.0 3.9 3.6 3.9 3.8 3.9 3.6 3.8 3.9 0.7 0.0 1.1 22.5 0.9 0.8 0.3 0.3 0.0 10.0 0.6 1.3 1.1 2.8 0.8 0.0 12.5 0.0 0.4 0.1 0.0 0.3 119.2 0.7 0.7 0.8 0.0 8.4 11.6 2.6 0.0 0.6 1.1 0.4 0.0 2.7 2.5 134.6 0.5 5.0 8.6 0.2 0.0 2.2 1.0 126.5 1.2 1.3 0.0 5.6 1.9 2.3 2.1 3.0 3.1 2.3 0.5 1.9 0.7 0.2 0.0 0.3 0.3 6.0 6.6 6.2 2.4 1.3 1.5 0.0 0.3 0.3 1.2 3.2 0.1 0.1 ITK "EMT, LYK, PSCTK2" ENSG00000113263 "IL2 inducible T cell kinase" Q08881 5 157142933-157255185 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 57.9" "Group enriched" "Detected in some" 6 "dendritic cells: 51.7;granulocytes: 31.8;NK-cells: 42.2;Plasma cells: 34.0;T-cells: 115.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 23 "gdT-cell: 39.6;MAIT T-cell: 26.4;memory CD4 T-cell: 55.6;memory CD8 T-cell: 54.9;naive CD4 T-cell: 78.2;naive CD8 T-cell: 65.0;NK-cell: 29.3;T-reg: 73.2" "Group enriched" "Detected in many" 23 "NK-cells: 29.3;T-cells: 78.2" "Group enriched" "Detected in some" 10 "JURKAT: 62.2;MOLT-4: 23.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043670 Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA043670: " "unprognostic (2.08e-3)" "unprognostic (6.57e-4)" "unprognostic (5.06e-3)" "unprognostic (4.96e-5)" "unprognostic (1.52e-2)" "unprognostic (1.12e-4)" "unprognostic (8.45e-4)" "unprognostic (1.56e-2)" "unprognostic (1.87e-2)" "unprognostic (5.99e-3)" "unprognostic (1.76e-1)" "unprognostic (2.52e-1)" "unprognostic (4.52e-6)" "unprognostic (3.64e-1)" "unprognostic (4.42e-2)" "unprognostic (1.46e-1)" "unprognostic (3.26e-2)" 1.0 0.3 0.0 15.9 0.0 3.7 0.9 0.0 0.0 1.0 0.0 1.4 0.7 0.4 0.0 1.4 0.4 4.2 0.2 0.0 0.0 0.3 1.6 3.1 29.3 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.4 1.5 0.0 0.3 0.1 0.0 0.2 4.0 0.5 0.0 10.5 3.1 0.5 0.0 57.9 0.5 0.0 24.6 3.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 3.9 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 62.2 0.0 0.0 0.0 0.0 23.7 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 39.6 0.0 26.4 0.0 55.6 54.9 0.1 0.0 78.2 65.0 1.3 29.3 2.3 0.1 73.2 44.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 6.2 0.0 4.0 2.7 0.6 0.0 0.0 0.0 0.4 0.4 0.9 0.0 0.6 1.8 0.0 0.1 51.7 0.1 0.0 0.1 8.5 0.2 0.3 0.8 0.0 1.7 0.2 0.0 0.0 1.1 7.7 0.4 31.8 0.1 1.8 1.0 0.0 0.0 0.2 0.0 0.0 1.6 5.1 6.7 0.0 2.9 1.8 1.0 2.8 0.0 42.2 0.0 0.1 0.0 0.0 0.0 34.0 0.3 0.0 0.4 0.0 0.0 0.0 1.0 1.0 0.0 0.0 0.2 3.4 0.1 115.7 0.0 0.1 0.6 ITPRIPL1 KIAA1754L ENSG00000198885 "ITPRIP like 1" Q6GPH6 2 96325317-96330517 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.8" "Group enriched" "Detected in many" 10 "Early spermatids: 170.7;Late spermatids: 145.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 12.9" "Lineage enriched" "Detected in many" 5 "T-cells: 12.9" "Cell line enhanced" "Detected in many" "HEK 293: 30.9;HEL: 32.0;MOLT-4: 34.5;RPMI-8226: 33.0;U-698: 35.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "unprognostic (1.26e-3)" "unprognostic (3.56e-3)" "unprognostic (4.78e-2)" "unprognostic (9.43e-2)" "unprognostic (2.22e-1)" "unprognostic (6.56e-4)" "unprognostic (3.04e-2)" "unprognostic (2.87e-1)" "unprognostic (6.50e-2)" "unprognostic (5.36e-2)" "unprognostic (8.99e-2)" "unprognostic (1.29e-1)" "unprognostic (2.41e-5)" "unprognostic (4.97e-2)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (6.39e-2)" 3.4 0.4 0.5 2.9 1.0 1.1 3.8 3.2 0.7 0.9 0.3 0.9 1.2 0.5 0.5 1.5 0.8 1.6 1.3 0.5 0.5 0.5 0.5 1.4 3.9 0.9 0.5 0.4 1.4 0.5 0.4 1.2 0.8 2.0 0.9 0.9 7.5 1.5 1.5 0.8 1.7 1.0 0.6 2.6 1.2 27.8 0.6 5.1 0.7 2.0 4.2 1.5 1.2 0.8 0.0 0.0 7.3 0.1 0.8 1.9 8.3 1.6 8.7 7.2 14.1 3.3 0.3 0.0 0.1 3.1 0.1 0.7 25.4 0.0 8.1 15.7 30.9 32.0 0.2 14.4 3.9 0.1 0.0 5.4 0.0 8.3 0.0 0.0 4.7 20.4 0.0 10.6 0.2 0.0 34.5 5.0 10.5 0.0 0.0 22.7 23.1 33.0 0.3 0.0 21.2 14.2 0.0 0.0 0.1 4.4 0.0 5.3 2.4 0.0 0.8 0.1 0.1 15.4 21.4 35.3 4.1 0.0 6.8 0.4 0.2 0.0 10.2 0.2 12.9 1.6 3.3 9.7 1.2 0.4 0.7 4.1 0.1 2.7 0.0 0.5 6.3 2.3 0.5 1.0 3.2 0.7 0.5 0.5 0.9 0.5 0.8 0.6 0.6 0.8 9.4 3.2 0.0 0.0 2.3 0.3 4.8 1.8 2.2 0.7 3.6 2.9 0.7 2.8 3.5 0.0 4.2 0.9 6.9 1.0 0.0 0.1 170.7 0.2 0.6 2.7 0.0 1.7 0.2 0.2 2.3 0.9 0.5 0.1 0.0 0.8 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.3 2.4 145.2 1.2 1.8 1.8 0.0 0.3 4.3 11.3 0.0 0.0 0.3 0.1 0.7 7.6 3.3 0.0 0.3 0.8 1.7 6.6 0.6 2.9 3.6 2.8 1.7 1.0 0.4 14.8 0.3 0.4 1.3 IZUMO1 "IZUMO, MGC34799, OBF" ENSG00000182264 "Izumo sperm-egg fusion 1" Q8IYV9 19 48740852-48746909 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 18.9" "Group enriched" "Detected in some" 44 "Early spermatids: 156.4;Late spermatids: 112.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "hTCEpi: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA038104 Enhanced NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "HPA038104: AB_10670655" "unprognostic (2.03e-1)" "unprognostic (1.86e-3)" "unprognostic (3.73e-2)" "unprognostic (1.37e-2)" "unprognostic (1.17e-2)" "unprognostic (7.92e-2)" "unprognostic (3.49e-2)" "unprognostic (2.53e-4)" "unprognostic (3.61e-2)" "unprognostic (1.69e-2)" "unprognostic (1.45e-1)" "unprognostic (4.83e-2)" "unprognostic (1.32e-2)" "unprognostic (3.68e-1)" "unprognostic (2.92e-1)" "unprognostic (4.31e-3)" "unprognostic (6.92e-2)" 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.7 0.3 0.0 0.0 0.0 0.6 0.1 0.4 0.2 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.9 18.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.1 0.3 0.7 2.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 156.4 0.3 0.2 2.3 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.9 0.0 0.0 2.9 0.0 0.4 0.0 0.3 0.5 2.0 0.0 1.3 112.7 1.2 0.9 1.8 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.2 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.5 3.0 1.2 0.1 0.0 0.0 0.1 0.2 0.0 0.2 JADE3 "JADE-3, KIAA0215, PHF16" ENSG00000102221 "Jade family PHD finger 3" Q92613 X 46912276-47061242 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 37.2;Oligodendrocytes: 36.8;Spermatocytes: 42.7;Spermatogonia: 35.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.8;naive B-cell: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 65.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA006007, HPA064697" Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA006007: AB_1079605, HPA064697: AB_2685326" "unprognostic (1.39e-1)" "unprognostic (2.53e-1)" "unprognostic (2.24e-1)" "unprognostic (1.52e-3)" "unprognostic (1.18e-2)" "unprognostic (3.01e-2)" "unprognostic (1.05e-3)" "unprognostic (1.59e-1)" "unprognostic (6.83e-3)" "unprognostic (4.55e-2)" "unprognostic (8.97e-3)" "unprognostic (2.82e-1)" "unprognostic (4.25e-2)" "unprognostic (4.42e-2)" "unprognostic (2.69e-1)" "unprognostic (8.18e-2)" "unprognostic (9.70e-2)" 3.5 10.7 3.5 3.1 4.9 2.0 6.3 5.1 5.1 5.6 2.7 3.6 2.2 6.0 15.9 3.5 3.9 3.2 3.1 3.2 4.1 3.7 7.6 3.6 4.9 6.6 4.4 7.1 8.3 3.3 1.1 15.4 6.2 4.2 3.4 2.5 3.5 7.2 1.7 3.3 4.6 5.0 5.0 5.0 4.1 12.1 5.2 7.2 4.1 2.6 6.1 4.7 2.6 8.8 12.1 10.6 17.2 11.9 6.2 4.6 65.7 7.1 5.9 7.8 8.7 12.3 10.3 0.1 4.9 5.2 11.6 4.7 21.1 5.7 11.2 32.6 13.8 9.6 11.9 12.0 10.2 7.3 5.0 3.5 7.8 5.5 17.7 4.8 14.9 18.1 6.7 5.6 6.1 12.5 26.5 8.9 13.6 7.8 9.0 27.0 19.4 16.9 6.6 11.0 14.8 13.1 20.4 18.7 11.3 28.3 12.4 7.6 9.3 8.2 14.2 11.7 4.7 4.3 4.0 22.7 2.3 6.1 8.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.1 0.7 0.0 0.2 3.5 4.9 5.1 5.1 3.2 4.1 6.6 4.4 6.2 5.0 5.2 8.8 4.1 0.0 7.8 1.0 14.4 4.2 2.3 1.8 2.2 1.5 9.9 4.2 5.4 1.5 1.6 5.5 0.0 9.6 0.1 2.0 0.0 2.4 1.1 3.9 3.9 5.1 8.4 6.5 5.5 3.6 10.3 2.0 2.6 4.4 0.0 9.7 6.1 13.3 1.8 0.0 12.7 2.6 6.1 1.0 5.7 3.7 4.7 1.4 3.6 14.0 2.8 1.2 1.0 37.2 36.8 3.1 1.1 3.8 1.9 4.1 0.5 2.9 1.2 2.3 6.6 1.9 2.8 42.7 35.3 5.8 8.1 14.2 0.7 3.5 2.4 3.7 JAKMIP1 "FLJ31564, Gababrbp, JAMIP1, MARLIN1" ENSG00000152969 "Janus kinase and microtubule interacting protein 1" Q96N16 4 6026199-6200591 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 31.1;pituitary gland: 10.2;retina: 17.0" "Cell type enhanced" "Detected in some" "Astrocytes: 35.6;dendritic cells: 17.6;Excitatory neurons: 82.9;Inhibitory neurons: 53.6;Muller glia cells: 61.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 17 "gdT-cell: 25.3;MAIT T-cell: 11.2;memory CD4 T-cell: 11.2;memory CD8 T-cell: 22.6;naive CD8 T-cell: 10.1;T-reg: 36.7" "Lineage enriched" "Detected in many" 33 "T-cells: 36.7" "Cell line enhanced" "Detected in some" "Daudi: 15.8;JURKAT: 14.3;MOLT-4: 45.2;SCLC-21H: 18.6;U-266/70: 26.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044570 Uncertain NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 10: Brain - Neuronal signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA044570: AB_2678995" "unprognostic (4.79e-2)" "unprognostic (3.46e-3)" "unprognostic (4.90e-2)" "unprognostic (1.73e-2)" "unprognostic (5.34e-2)" "unprognostic (3.86e-3)" "unprognostic (6.16e-2)" "unprognostic (6.69e-3)" "unprognostic (4.25e-4)" "unprognostic (7.14e-2)" "unprognostic (4.57e-3)" "unprognostic (1.13e-1)" "unprognostic (3.70e-8)" "unprognostic (1.85e-2)" "unprognostic (3.15e-1)" "unprognostic (4.23e-2)" "unprognostic (2.96e-3)" 0.3 4.8 21.4 1.0 31.1 1.3 0.1 5.0 30.4 0.2 0.1 1.0 0.2 0.1 0.1 0.3 0.2 0.5 0.1 21.6 22.0 0.2 0.3 0.9 3.0 9.0 13.5 0.5 0.6 0.0 10.2 0.0 12.8 4.2 0.2 17.0 0.7 0.1 0.1 0.1 1.1 0.2 7.1 2.6 0.6 5.2 16.2 0.3 0.7 0.0 0.6 0.7 0.3 20.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 2.6 0.0 0.0 0.0 0.0 8.7 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.4 45.2 0.0 3.4 0.0 2.6 2.3 0.0 0.7 0.0 0.0 18.6 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.3 4.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 25.3 0.0 11.2 0.3 11.2 22.6 0.0 0.2 0.8 10.1 0.1 1.1 0.0 0.1 36.7 5.4 21.4 31.1 5.0 30.4 21.6 22.0 9.0 13.5 12.8 7.1 16.2 20.3 0.2 0.0 0.0 35.6 0.8 0.0 0.0 0.0 0.0 1.5 0.2 0.1 0.8 0.0 0.0 0.0 2.1 0.0 17.6 0.0 0.0 0.0 1.5 0.1 0.2 0.1 0.0 0.4 82.9 0.0 0.0 0.5 2.6 0.8 0.0 0.2 0.0 0.0 0.1 3.3 53.6 0.0 0.0 1.3 0.5 2.4 0.0 0.5 0.0 7.5 0.3 61.2 12.3 7.1 3.1 0.1 0.0 0.0 2.3 1.3 0.0 0.1 0.0 5.4 0.0 0.0 0.2 0.9 4.6 0.0 0.1 0.0 16.2 0.4 0.0 0.0 JCAD KIAA1462 ENSG00000165757 "Junctional cadherin 5 associated" Q9P266 10 30012803-30115494 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 106.8;Endothelial cells: 30.3;Granulosa cells: 72.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 29.3;HUVEC TERT2: 29.9;LHCN-M2: 24.9;TIME: 67.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017956 Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Cell Junctions" "HPA017956: AB_1852408" "unprognostic (1.78e-1)" "unprognostic (8.33e-2)" "unprognostic (5.37e-2)" "unprognostic (8.07e-2)" "unprognostic (6.32e-2)" "unprognostic (7.09e-2)" "unprognostic (9.36e-2)" "unprognostic (1.28e-1)" "unprognostic (1.16e-1)" "unprognostic (4.93e-2)" "unprognostic (1.33e-1)" "unprognostic (3.08e-2)" "prognostic unfavorable (2.54e-4)" "prognostic unfavorable (2.01e-4)" "unprognostic (1.41e-1)" "unprognostic (1.13e-2)" "unprognostic (1.34e-2)" 31.2 7.5 13.5 5.2 21.2 0.1 13.0 5.1 13.0 6.5 3.1 36.0 1.4 17.3 7.5 5.9 12.5 10.4 18.3 10.8 7.2 6.7 1.8 24.2 3.5 12.5 8.4 10.9 16.9 4.9 4.5 33.6 10.1 7.8 3.9 13.1 2.4 9.5 9.9 3.7 3.7 17.3 7.3 0.9 4.5 14.0 13.3 6.1 13.6 14.8 1.8 18.3 4.4 8.1 15.3 6.7 5.9 0.0 3.7 0.9 8.6 8.1 8.5 1.2 2.0 2.6 0.1 0.0 0.6 29.3 1.7 0.3 1.6 0.5 3.3 1.7 3.6 0.0 0.0 0.1 16.0 0.0 1.0 9.1 0.2 19.9 1.5 0.5 29.9 0.4 0.0 0.0 24.9 0.5 0.0 0.7 1.2 0.9 10.2 0.0 3.3 0.0 1.2 0.3 0.8 0.1 0.3 0.1 0.0 8.4 0.0 1.4 67.8 14.9 3.6 4.7 0.7 6.2 0.8 0.0 3.5 10.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 21.2 5.1 13.0 10.8 7.2 12.5 8.4 10.1 7.3 13.3 8.1 106.8 0.0 3.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 2.7 0.4 0.0 0.0 16.4 0.0 1.3 8.5 30.3 0.0 0.0 0.0 0.4 0.9 2.2 0.0 0.8 1.3 72.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 2.9 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 3.4 0.2 7.1 0.0 0.0 JHY "C11orf63, FLJ23554" ENSG00000109944 "Junctional cadherin complex regulator" Q6NUN7 11 122882683-122963862 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 35.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 12.8;Endometrial ciliated cells: 41.5;Glandular and luminal cells: 8.7;Proximal tubular cells: 12.0;Respiratory ciliated cells: 19.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "GAMG: 13.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA039612, HPA040344, HPA077658, HPA077748" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Golgi apparatus" "HPA039612: AB_10674424, HPA040344: AB_2676931, HPA077658: AB_2732355, HPA077748: AB_2732360" "unprognostic (5.27e-2)" "unprognostic (1.12e-1)" "unprognostic (3.93e-2)" "prognostic favorable (7.94e-5)" "unprognostic (9.97e-5)" "unprognostic (1.64e-1)" "unprognostic (2.02e-3)" "unprognostic (1.94e-3)" "unprognostic (1.77e-1)" "unprognostic (1.49e-1)" "unprognostic (4.13e-2)" "unprognostic (2.97e-1)" "prognostic favorable (8.77e-4)" "unprognostic (6.46e-3)" "unprognostic (2.54e-1)" "prognostic unfavorable (2.58e-4)" "unprognostic (7.79e-2)" 6.0 1.8 1.7 2.2 2.7 1.1 3.6 3.4 2.4 3.1 17.3 3.5 1.5 2.1 2.7 1.8 7.4 2.6 2.2 1.8 3.8 7.8 0.4 4.5 2.2 4.1 5.4 3.2 2.8 5.6 4.8 1.3 3.8 3.5 1.7 1.6 1.4 2.5 0.2 1.9 1.9 2.0 3.8 2.5 2.0 35.7 3.2 3.2 5.1 0.8 2.0 2.6 1.8 3.6 2.8 3.9 2.2 0.1 0.6 0.4 0.7 5.9 6.8 2.5 1.1 0.3 10.3 0.1 1.5 9.1 13.6 2.4 2.7 1.4 1.1 9.5 2.8 0.1 1.8 0.1 0.9 1.7 4.7 2.8 7.4 0.4 0.6 6.3 3.8 4.1 0.0 0.1 2.0 1.8 0.1 0.6 0.3 8.2 3.5 1.0 0.0 1.3 7.0 3.2 5.8 4.2 7.1 3.9 2.6 2.8 4.7 0.6 1.2 7.9 1.0 0.2 4.8 0.1 0.0 0.1 2.1 2.1 5.3 0.5 0.3 0.1 1.3 0.1 1.8 1.1 1.3 1.7 2.4 0.6 0.9 1.0 0.4 2.4 0.1 0.6 0.3 0.5 1.7 2.7 3.4 2.4 1.8 3.8 4.1 5.4 3.8 3.8 3.2 3.6 4.4 12.8 4.4 0.0 1.1 0.0 0.0 0.0 0.0 0.0 3.3 3.2 0.0 0.0 7.4 5.5 0.0 0.2 2.2 0.0 3.9 5.5 0.0 41.5 3.1 1.1 0.0 0.0 0.0 1.4 0.9 2.2 0.0 8.7 0.0 2.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 2.6 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.7 0.0 0.0 12.0 19.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.3 1.8 1.3 0.0 0.0 JUP "CTNNG, DP3, DPIII, PDGB, PKGB" ENSG00000173801 "Junction plakoglobin" P14923 17 41754604-41786931 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cancer-related genes, Cardiomyopathy, Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 952.2;skin 1: 932.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 315.9;Pancreatic endocrine cells: 356.2;Squamous epithelial cells: 318.3;Suprabasal keratinocytes: 383.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 13.1;eosinophil: 28.7;intermediate monocyte: 22.6;memory B-cell: 13.5;myeloid DC: 14.5;naive B-cell: 11.7;non-classical monocyte: 43.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 1090.1;OE19: 3919.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002139, HPA032047" Supported Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 64000000 "Cluster 14: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" Vesicles "CAB002139: AB_563468, HPA032047: AB_2674124" "unprognostic (3.96e-3)" "unprognostic (3.40e-1)" "unprognostic (2.32e-1)" "unprognostic (4.71e-3)" "unprognostic (2.49e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (8.11e-3)" "unprognostic (1.41e-2)" "unprognostic (9.85e-3)" "unprognostic (2.29e-3)" "unprognostic (9.60e-2)" "prognostic favorable (2.06e-10)" "unprognostic (2.50e-1)" "unprognostic (9.49e-2)" "unprognostic (9.05e-2)" "unprognostic (1.51e-2)" 46.5 16.0 13.6 23.6 21.6 20.7 68.6 20.8 18.9 243.7 25.8 94.9 88.1 57.0 15.3 952.2 69.9 39.8 145.1 14.6 14.3 120.7 70.9 57.1 15.7 20.7 16.2 46.2 59.6 19.9 37.3 51.5 19.6 68.0 49.0 4.7 226.4 41.8 110.8 932.4 95.7 23.1 14.8 22.7 86.3 12.5 16.2 29.6 86.4 62.2 92.0 68.7 432.6 33.6 268.8 217.8 21.7 18.5 0.2 0.1 330.6 15.3 89.2 5.9 5.2 332.6 289.0 5.4 157.8 9.7 7.5 1090.1 31.6 242.4 1.0 0.6 74.2 11.6 165.1 74.4 34.7 7.3 113.6 0.5 538.6 0.9 43.9 64.2 96.1 7.0 99.6 94.0 0.0 342.6 1.9 96.5 42.3 3919.9 36.2 313.5 0.2 202.5 165.8 674.0 52.2 38.6 33.8 652.1 1.9 98.6 545.9 8.0 152.4 0.3 14.8 6.8 5.1 8.2 31.2 5.5 1.5 12.7 2.6 3.9 13.1 28.7 0.0 22.6 0.0 13.5 0.0 0.2 14.5 11.7 0.2 0.1 0.6 0.8 43.8 4.5 0.1 5.7 13.6 21.6 20.8 18.9 14.6 14.3 20.7 16.2 19.6 14.8 16.2 33.6 56.9 60.9 36.8 4.6 10.6 196.9 218.5 104.5 100.2 1.9 87.3 77.0 87.8 48.6 80.9 132.4 4.2 98.9 1.1 315.9 27.4 212.2 28.5 112.6 21.1 55.2 66.8 3.4 0.5 135.4 167.3 25.6 136.1 247.0 11.4 16.5 41.4 34.1 14.4 0.0 1.6 125.0 81.4 7.7 32.7 8.3 5.0 10.9 12.4 2.8 6.3 18.2 0.0 7.1 13.6 356.2 223.7 0.0 3.9 220.1 141.1 35.6 45.7 4.3 6.6 37.4 18.8 2.5 4.5 318.3 383.3 185.7 6.1 3.2 129.2 301.6 KAT2B "GCN5, GCN5L, P/CAF, PCAF" ENSG00000114166 "Lysine acetyltransferase 2B" Q92831 3 20040446-20154404 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 165.2;Oligodendrocyte precursor cells: 418.2;Oligodendrocytes: 175.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002470, CAB004526, HPA055839, HPA073897" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm Cytosol "CAB004526: AB_2128417, HPA002470: , HPA055839: AB_2682938, HPA073897: " "unprognostic (2.91e-2)" "unprognostic (6.85e-3)" "unprognostic (9.05e-2)" "unprognostic (2.25e-1)" "unprognostic (2.66e-2)" "unprognostic (3.01e-3)" "unprognostic (2.44e-1)" "unprognostic (3.83e-3)" "unprognostic (2.44e-2)" "unprognostic (1.03e-1)" "unprognostic (5.23e-3)" "unprognostic (7.13e-2)" "unprognostic (7.03e-2)" "unprognostic (2.26e-2)" "unprognostic (1.59e-1)" "unprognostic (5.16e-2)" "unprognostic (4.63e-2)" 17.9 9.9 38.7 15.4 46.5 48.0 10.3 39.1 40.3 14.9 33.8 13.8 17.7 12.3 8.1 27.4 11.7 12.6 35.9 34.4 42.2 16.6 39.3 16.2 22.4 41.7 44.9 27.7 18.7 51.0 10.2 13.7 43.0 14.5 12.5 33.9 37.6 13.0 60.2 14.3 21.5 13.6 37.1 19.8 13.9 2.7 42.2 23.6 14.4 56.1 20.1 11.9 15.1 45.1 2.7 6.9 3.8 6.2 15.1 14.2 8.8 8.8 13.0 9.1 13.3 2.1 4.5 24.0 3.6 16.7 11.5 2.0 9.4 2.8 7.6 21.8 9.0 21.0 10.7 0.7 7.1 3.2 26.2 6.1 5.0 7.9 5.1 16.0 8.8 5.8 13.7 32.9 13.0 3.3 7.0 6.4 1.6 6.7 6.8 9.1 7.1 5.1 12.4 14.2 1.9 4.1 4.9 7.9 30.5 5.9 8.2 14.2 8.5 15.3 6.1 5.8 10.1 12.3 27.6 5.7 13.9 13.8 33.0 0.6 0.4 1.3 1.5 0.7 1.5 0.4 1.3 1.1 0.4 0.8 0.4 0.8 2.4 0.5 0.5 1.2 2.2 0.3 38.7 46.5 39.1 40.3 34.4 42.2 41.7 44.9 43.0 37.1 42.2 45.1 15.5 32.1 20.8 165.2 11.9 8.5 11.3 2.2 3.4 14.6 5.5 5.0 64.1 4.3 10.4 5.5 4.2 7.3 19.5 16.6 11.7 3.8 3.8 6.4 5.7 14.6 11.5 52.2 22.4 4.4 1.1 11.7 3.6 13.1 10.8 12.3 20.7 33.6 7.7 15.2 32.1 7.3 4.1 22.8 23.3 1.8 6.5 16.0 17.8 52.5 11.1 14.8 14.4 418.2 175.4 3.3 2.4 5.3 19.9 7.1 24.7 6.2 12.7 11.9 6.6 25.2 9.0 0.8 1.4 10.0 12.9 9.9 23.5 2.9 3.8 8.0 KCNJ2 "IRK1, Kir2.1, LQT7" ENSG00000123700 "Potassium inwardly rectifying channel subfamily J member 2" P63252 17 70168673-70180044 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Atrial fibrillation, Disease variant, FDA approved drug targets, Long QT syndrome, Short QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 42.9;parathyroid gland: 36.0" "Group enriched" "Detected in many" 4 "Horizontal cells: 240.6;Oligodendrocytes: 164.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 6.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 30.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 30.4" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 8.9;HUVEC TERT2: 6.3;REH: 7.5;RH-30: 29.2;U-138 MG: 10.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029109 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 62: Horizontal cells - Visual perception" "HPA029109: AB_10602913" "unprognostic (1.32e-1)" "unprognostic (1.24e-1)" "unprognostic (1.18e-1)" "unprognostic (6.22e-2)" "unprognostic (3.50e-1)" "unprognostic (6.36e-3)" "unprognostic (1.22e-2)" "unprognostic (3.14e-1)" "unprognostic (1.09e-1)" "unprognostic (1.62e-1)" "unprognostic (3.64e-2)" "unprognostic (1.03e-1)" "unprognostic (1.74e-3)" "unprognostic (6.15e-3)" "unprognostic (9.60e-3)" "unprognostic (4.89e-2)" "unprognostic (5.49e-3)" 1.9 0.8 7.2 5.1 19.5 1.9 4.9 13.4 13.1 0.9 0.0 3.9 0.9 0.9 0.6 2.9 6.6 1.4 9.8 5.9 11.8 1.0 1.3 2.1 1.3 18.6 16.2 0.7 0.4 36.0 0.6 6.3 18.2 1.8 3.2 7.6 1.3 1.8 9.7 4.7 1.4 1.0 10.5 7.3 0.8 0.3 14.5 1.8 1.2 8.4 1.5 1.9 1.8 42.9 0.0 0.9 1.8 0.0 1.9 0.5 0.0 0.6 4.5 0.1 0.1 0.0 0.0 0.0 0.4 0.5 1.2 0.5 0.1 0.3 0.1 0.0 0.2 0.0 0.6 0.0 5.4 0.0 0.0 2.0 0.1 2.8 0.3 8.9 6.3 0.0 0.0 0.0 1.9 0.0 0.7 0.0 0.2 0.8 0.2 7.5 29.2 0.0 0.7 0.0 0.4 0.8 0.5 0.1 0.0 3.5 0.3 0.5 0.1 10.6 0.1 0.1 2.4 0.0 0.0 0.1 2.3 0.0 1.5 4.2 3.5 5.6 0.0 6.9 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 30.4 0.0 7.3 0.2 0.0 0.8 7.2 19.5 13.4 13.1 5.9 11.8 18.6 16.2 18.2 10.5 14.5 42.9 12.0 0.0 3.2 0.0 0.6 8.2 4.1 4.9 16.5 43.5 5.8 9.3 19.3 0.0 1.9 1.8 0.0 0.5 0.1 13.5 0.0 0.1 0.3 2.3 0.2 16.0 10.7 0.4 3.8 0.0 0.4 1.7 4.1 1.6 0.0 0.1 3.3 0.1 6.8 240.6 16.2 2.7 0.0 36.9 7.4 0.0 1.5 7.8 3.6 2.8 8.2 5.8 0.0 1.5 164.7 0.0 12.3 1.2 0.0 2.2 0.9 0.1 4.9 5.2 0.0 3.9 2.6 0.1 0.9 6.9 3.3 1.4 0.8 0.2 8.5 0.3 KCNJ3 "GIRK1, KGA, Kir3.1" ENSG00000162989 "Potassium inwardly rectifying channel subfamily J member 3" P48549 2 154697855-154858354 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.7" "Group enriched" "Detected in many" 5 "Excitatory neurons: 309.6;Horizontal cells: 124.5;Inhibitory neurons: 431.3" "Group enriched" "Detected in many" 5 "breast cancer: 12.2;renal cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 1.5;SH-SY5Y: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024231, HPA064138" Uncertain Approved "Plasma membrane,Mitochondria" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "Plasma membrane" "HPA024231: AB_1855558, HPA064138: " "unprognostic (1.45e-1)" "unprognostic (9.42e-2)" "unprognostic (2.66e-2)" "unprognostic (4.49e-4)" "unprognostic (8.89e-2)" "unprognostic (6.81e-2)" "unprognostic (7.24e-3)" "unprognostic (1.15e-2)" "unprognostic (4.25e-3)" "unprognostic (3.72e-3)" "unprognostic (3.33e-1)" "unprognostic (8.90e-3)" "unprognostic (3.75e-2)" "unprognostic (5.59e-1)" "unprognostic (2.32e-1)" "unprognostic (1.17e-1)" 0.5 1.4 5.7 0.1 8.7 0.1 0.3 32.7 17.0 1.6 4.7 0.8 10.7 0.1 1.1 0.1 0.4 1.3 15.1 14.6 3.7 10.5 3.1 0.2 0.0 2.2 4.3 0.1 2.1 10.4 6.8 0.0 2.4 6.5 0.8 5.0 0.0 11.3 5.3 0.1 9.5 0.2 1.6 0.4 0.7 0.4 4.1 0.0 0.1 0.2 0.0 0.4 0.6 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.4 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.3 0.3 0.2 0.1 0.1 0.1 5.7 8.7 32.7 17.0 14.6 3.7 2.2 4.3 2.4 1.6 4.1 6.4 0.3 0.0 0.0 38.8 0.0 0.8 5.3 0.0 0.0 10.9 3.7 1.7 49.0 5.7 0.0 20.2 14.6 0.0 0.0 0.1 5.9 0.1 0.3 0.0 0.0 1.3 31.1 0.0 309.6 3.2 0.0 5.4 0.0 0.0 0.0 0.0 0.0 1.3 0.1 124.5 431.3 7.0 0.0 0.0 2.1 0.0 6.2 0.6 1.8 5.6 0.0 0.7 0.0 32.6 6.8 0.0 1.2 4.1 0.0 6.1 16.2 8.7 0.0 3.9 0.0 8.0 1.6 0.4 0.3 0.0 1.8 0.0 0.8 1.9 8.4 4.7 KCNK13 "K2p13.1, THIK-1, THIK1" ENSG00000152315 "Potassium two pore domain channel subfamily K member 13" Q9HB14 14 90061994-90185853 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 5.6;parathyroid gland: 6.0;testis: 9.2" "Cell type enriched" "Detected in some" 4 "Microglial cells: 41.2" "Cancer enhanced" "Detected in many" "testis cancer: 5.3" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.2" "Lineage enhanced" "Detected in single" "dendritic cells: 1.2" "Cell line enhanced" "Detected in some" "GAMG: 1.0;RT4: 1.9;SuSa: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA003514 Approved Approved "Nuclear speckles,Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Cell Junctions" "HPA003514: AB_2666978" "unprognostic (1.40e-1)" "unprognostic (1.73e-1)" "unprognostic (6.17e-2)" "unprognostic (6.31e-2)" "unprognostic (2.56e-1)" "unprognostic (5.55e-2)" "unprognostic (3.56e-2)" "unprognostic (3.98e-2)" "unprognostic (2.40e-1)" "unprognostic (2.34e-1)" "unprognostic (1.85e-1)" "unprognostic (3.45e-2)" "unprognostic (1.97e-1)" "unprognostic (2.04e-2)" "unprognostic (6.32e-2)" "unprognostic (1.46e-1)" "unprognostic (5.65e-2)" 0.3 0.8 1.7 1.7 1.5 0.0 0.2 0.9 1.9 0.1 5.6 0.4 0.5 0.2 1.0 0.2 0.3 0.4 1.6 1.6 1.4 3.9 0.5 0.4 0.6 1.6 2.3 0.1 0.3 6.0 0.3 0.2 1.8 0.1 0.5 0.0 0.2 0.4 0.0 0.1 0.5 0.3 1.8 0.6 0.4 9.2 2.2 1.1 1.9 0.0 0.5 0.5 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.4 0.0 0.0 0.3 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.1 1.9 0.7 0.2 0.0 0.7 0.5 2.9 0.0 0.7 0.0 0.0 0.8 0.0 0.3 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 1.7 1.5 0.9 1.9 1.6 1.4 1.6 2.3 1.8 1.8 2.2 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.8 0.4 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 6.3 0.0 0.4 0.0 0.0 6.0 0.0 4.4 0.0 0.0 4.0 8.1 0.6 0.0 3.2 0.0 41.2 9.0 0.0 0.0 3.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.6 0.0 0.3 0.1 0.1 0.4 0.0 0.1 KCNMB4 ENSG00000135643 "Potassium calcium-activated channel subfamily M regulatory beta subunit 4" Q86W47 12 70366290-70434292 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.2;choroid plexus: 18.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 95.7;Hepatic stellate cells: 37.1;Inhibitory neurons: 45.0;Oligodendrocytes: 86.9" "Cancer enhanced" "Detected in many" "glioma: 10.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 7.7;RH-30: 8.2;RT4: 9.3;SuSa: 7.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072287 Enhanced Approved Approved Cytosol NA NA "Cluster 70: Brain - Nervous system development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA072287: AB_2686507" "unprognostic (3.90e-1)" "unprognostic (1.72e-2)" "unprognostic (2.69e-2)" "unprognostic (2.62e-2)" "unprognostic (6.98e-2)" "unprognostic (1.13e-3)" "unprognostic (1.85e-1)" "unprognostic (2.48e-2)" "unprognostic (3.50e-1)" "unprognostic (2.95e-2)" "unprognostic (3.75e-1)" "unprognostic (2.47e-2)" "unprognostic (2.19e-2)" "unprognostic (1.96e-1)" "unprognostic (1.78e-1)" "unprognostic (4.62e-2)" "unprognostic (1.05e-2)" 2.3 14.9 35.3 1.1 39.5 0.2 2.0 29.7 43.5 3.1 18.9 8.6 1.0 1.8 1.1 1.0 1.7 1.4 4.7 36.4 29.7 3.7 0.5 6.1 1.3 38.5 32.2 2.6 0.5 0.2 1.9 2.5 32.1 3.2 1.2 1.9 1.7 2.1 2.4 2.6 3.0 1.2 28.9 1.2 2.1 2.1 38.4 1.3 2.1 1.5 1.0 2.5 2.6 54.2 0.0 0.3 4.9 2.7 0.3 0.2 0.5 0.6 0.9 0.2 0.7 0.2 1.8 2.4 0.3 0.0 1.0 0.0 5.3 0.8 0.2 1.1 3.1 1.3 1.1 2.9 0.0 0.1 0.1 1.4 0.1 0.0 0.0 0.5 0.2 3.5 0.0 0.0 0.9 0.7 1.8 0.4 7.7 0.1 5.6 2.6 8.2 0.2 0.2 9.3 2.4 2.9 0.7 0.9 0.0 7.3 2.7 0.1 0.1 0.3 1.3 0.1 0.3 1.7 0.0 2.5 0.4 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.3 0.4 0.6 0.0 0.0 0.0 0.0 0.1 0.1 35.3 39.5 29.7 43.5 36.4 29.7 38.5 32.2 32.1 28.9 38.4 54.2 8.5 0.0 0.6 2.6 1.1 3.2 0.2 0.4 0.6 23.1 2.8 1.9 4.3 0.0 0.2 23.9 0.0 0.2 2.1 0.1 0.0 0.1 0.9 4.7 1.1 8.7 0.0 3.2 95.7 0.0 0.4 9.6 0.0 3.4 0.0 7.2 37.1 0.7 1.2 0.0 45.0 0.4 0.0 10.8 2.6 2.2 6.5 2.9 1.8 20.6 0.7 1.5 0.0 13.6 86.9 0.0 0.0 18.0 0.2 0.8 0.0 9.7 0.0 3.0 0.0 12.8 5.1 2.2 7.8 0.2 5.5 0.3 1.4 14.0 0.5 0.0 KIAA0408 ENSG00000189367 KIAA0408 Q6ZU52 6 127438406-127459389 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.6;skeletal muscle: 28.3" "Group enriched" "Detected in some" 6 "Alveolar cells type 1: 93.0;Alveolar cells type 2: 27.1;Skeletal myocytes: 34.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 10.4;SCLC-21H: 33.3;SH-SY5Y: 17.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044035, HPA053341" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm Cytosol "HPA044035: AB_10964274, HPA053341: AB_2732578" "unprognostic (1.06e-1)" "unprognostic (4.36e-2)" "unprognostic (3.06e-1)" "unprognostic (1.09e-1)" "unprognostic (8.56e-4)" "unprognostic (1.00e-1)" "unprognostic (4.95e-2)" "unprognostic (6.05e-3)" "unprognostic (2.29e-1)" "unprognostic (5.94e-2)" "unprognostic (3.20e-2)" 16.8 2.3 16.9 0.9 18.4 0.0 3.7 20.1 32.6 4.3 8.0 9.7 0.9 2.9 1.8 6.2 2.0 1.6 2.1 18.2 17.4 1.2 0.7 13.2 0.3 16.7 16.9 2.5 0.8 0.0 13.9 0.3 17.2 4.3 3.6 8.7 1.8 1.1 28.3 1.0 4.3 1.8 18.0 2.0 5.4 4.0 17.7 0.3 0.9 10.4 0.2 6.0 3.6 19.6 0.0 2.1 10.4 0.0 0.8 1.7 0.0 0.2 1.3 1.1 2.7 0.0 0.0 0.0 0.0 0.2 7.0 0.0 1.0 0.0 1.6 0.8 0.2 0.0 0.0 0.0 0.1 0.0 0.0 4.0 0.0 4.3 0.0 0.9 0.0 1.2 0.0 0.0 1.2 0.0 4.7 0.0 4.8 0.0 0.0 0.0 2.6 0.0 0.2 0.0 33.3 17.8 0.0 0.0 0.2 0.0 0.0 1.1 0.0 5.3 0.8 0.0 1.9 0.0 0.0 0.0 4.7 0.3 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 18.4 20.1 32.6 18.2 17.4 16.7 16.9 17.2 18.0 17.7 19.6 0.4 93.0 27.1 0.0 0.0 0.0 0.1 0.0 0.0 3.3 0.0 0.4 0.2 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.1 0.7 0.0 0.3 8.4 0.0 0.0 0.0 0.3 0.3 0.6 0.9 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.1 3.6 1.1 0.0 34.3 0.5 1.0 0.1 0.0 0.0 0.1 0.1 3.4 0.0 0.0 KIAA0753 "MNR, OFIP" ENSG00000198920 KIAA0753 Q2KHM9 17 6578147-6640711 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Ciliopathy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 90.9;Excitatory neurons: 46.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA023057, HPA023494" Enhanced Approved Centrosome,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" "Centrosome, Cytosol" "HPA023057: AB_1852338, HPA023494: AB_1852339" "unprognostic (3.72e-2)" "unprognostic (5.91e-2)" "unprognostic (1.60e-2)" "unprognostic (2.93e-2)" "unprognostic (5.17e-2)" "unprognostic (1.47e-1)" "unprognostic (4.19e-3)" "unprognostic (1.47e-1)" "unprognostic (3.01e-3)" "unprognostic (1.82e-1)" "unprognostic (6.10e-3)" "unprognostic (1.47e-2)" "unprognostic (9.57e-2)" "unprognostic (1.37e-1)" "unprognostic (2.70e-1)" "unprognostic (1.55e-1)" "unprognostic (1.77e-3)" 4.9 5.7 6.8 4.6 6.8 3.5 7.3 3.8 7.3 8.4 10.5 7.1 3.5 8.5 11.0 7.1 10.1 5.2 4.1 7.2 6.6 8.7 3.7 5.3 5.0 4.3 4.9 10.1 5.6 14.0 8.8 5.3 3.6 7.7 6.9 10.8 5.7 8.3 2.1 5.7 5.4 8.4 3.4 7.6 6.5 16.6 6.0 8.5 9.0 2.7 5.1 6.4 6.4 5.5 19.9 16.1 19.4 13.2 7.2 11.9 7.7 10.5 10.0 15.1 14.0 11.1 4.8 7.9 7.1 10.4 9.9 18.4 17.8 10.1 23.9 8.1 15.1 4.3 14.8 8.7 12.0 6.9 9.3 7.1 12.9 13.7 13.0 15.5 11.8 9.1 9.9 1.0 12.3 5.9 7.7 6.2 11.8 9.7 8.1 11.1 6.8 2.5 13.9 12.9 7.3 12.7 13.2 3.9 8.9 12.5 6.5 4.5 11.1 13.1 6.7 7.6 16.8 1.8 2.6 2.8 9.8 4.5 10.6 0.0 0.7 0.6 0.5 0.7 0.6 0.8 0.5 0.5 0.4 0.4 0.3 0.3 1.9 0.4 0.4 0.6 0.4 0.2 6.8 6.8 3.8 7.3 7.2 6.6 4.3 4.9 3.6 3.4 6.0 5.5 5.4 6.4 12.3 25.8 3.4 3.2 2.9 2.6 4.6 3.8 5.9 5.2 3.6 7.2 8.3 0.0 16.7 2.4 2.9 5.2 0.0 4.1 90.9 13.2 9.5 5.7 7.2 3.0 46.6 3.8 1.1 6.3 9.7 5.8 1.3 12.9 3.9 2.1 2.5 10.1 29.2 3.9 4.1 3.1 0.6 15.4 4.4 3.2 0.0 25.3 2.8 2.1 2.1 27.2 14.7 3.9 4.9 3.4 5.6 3.6 2.2 2.9 29.3 12.1 0.0 5.9 5.4 15.1 7.8 5.0 2.4 1.2 3.1 9.3 4.4 2.7 KIAA1614 ENSG00000135835 KIAA1614 Q5VZ46 1 180912897-180951614 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 25.3" "Group enriched" "Detected in many" 13 "Bipolar cells: 95.3;Cone photoreceptor cells: 131.3;Rod photoreceptor cells: 176.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.3" "Cell line enhanced" "Detected in many" "RH-30: 17.8;SH-SY5Y: 44.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028227, HPA061684" Approved Approved "Nuclear membrane,Vesicles" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" "Nuclear membrane, Vesicles" "HPA028227: AB_10601765, HPA061684: AB_2684585" "unprognostic (3.23e-1)" "unprognostic (3.60e-2)" "unprognostic (3.17e-2)" "unprognostic (2.15e-2)" "unprognostic (1.05e-1)" "unprognostic (3.55e-2)" "unprognostic (8.76e-3)" "unprognostic (1.30e-1)" "unprognostic (1.38e-1)" "unprognostic (1.33e-1)" "unprognostic (3.15e-2)" "unprognostic (1.57e-1)" "unprognostic (8.61e-5)" "unprognostic (8.93e-2)" "unprognostic (8.88e-2)" "unprognostic (1.36e-2)" "unprognostic (1.35e-2)" 5.7 1.2 3.8 1.3 3.9 0.4 4.0 15.4 6.1 7.2 4.3 8.4 2.4 8.1 1.3 3.5 6.1 2.5 7.7 4.9 2.4 6.2 0.5 3.6 1.2 3.6 3.2 5.8 1.7 0.3 1.8 2.8 2.9 4.8 0.6 25.3 3.2 2.1 2.0 2.5 2.9 3.1 2.8 2.5 3.2 1.7 4.0 0.3 6.1 0.4 0.4 7.4 4.2 5.3 1.7 0.8 1.4 3.0 4.3 10.5 4.8 3.3 3.8 1.6 0.9 1.6 1.7 0.7 3.0 4.1 0.8 3.2 0.3 0.1 0.5 0.9 1.3 2.4 0.6 2.2 5.9 1.5 1.7 5.0 0.1 0.2 0.1 2.7 2.2 2.5 2.1 1.1 1.4 1.4 2.1 0.6 3.3 0.5 0.4 1.1 17.8 2.5 2.6 1.6 12.2 44.7 1.0 1.1 7.3 1.4 1.3 2.1 5.2 3.4 2.5 4.0 1.3 2.3 3.2 1.6 0.4 1.2 2.3 1.3 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.1 3.8 3.9 15.4 6.1 4.9 2.4 3.6 3.2 2.9 2.8 4.0 5.3 1.0 0.0 1.8 9.8 0.5 0.4 0.8 0.8 0.6 95.3 0.5 0.6 3.5 1.5 1.3 1.8 131.3 0.3 0.5 0.0 1.9 0.4 4.6 0.8 3.6 2.1 0.0 0.0 5.0 0.2 0.4 3.3 0.0 2.2 1.3 1.6 1.8 0.1 1.8 3.3 1.5 0.0 0.0 0.3 0.4 1.8 7.8 0.5 3.6 1.0 1.0 10.0 0.0 4.5 1.4 0.7 0.0 5.7 0.1 0.4 0.2 1.8 0.1 176.0 6.6 8.4 2.4 0.6 0.6 0.2 0.3 0.3 0.4 0.6 0.1 0.0 KIAA2012 ENSG00000182329 KIAA2012 2 202073255-202205188 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 6.9;choroid plexus: 3.1;fallopian tube: 9.2" "Group enriched" "Detected in some" 6 "Early spermatids: 38.9;Endometrial ciliated cells: 12.3;Excitatory neurons: 24.8;Late spermatids: 28.6;Respiratory ciliated cells: 43.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA077834 Enhanced NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 49: Ciliated cells - Cilium organization" "HPA077834: " "unprognostic (1.91e-2)" "unprognostic (3.17e-1)" "unprognostic (2.56e-1)" "unprognostic (5.35e-2)" "unprognostic (2.85e-2)" "unprognostic (3.22e-2)" "unprognostic (1.93e-2)" "unprognostic (1.43e-1)" "unprognostic (3.23e-1)" "unprognostic (7.35e-2)" "unprognostic (6.31e-2)" "unprognostic (7.81e-2)" "unprognostic (6.94e-5)" "unprognostic (1.60e-1)" "unprognostic (9.44e-2)" "unprognostic (3.37e-1)" "unprognostic (9.95e-3)" 0.0 0.0 1.0 0.0 2.0 0.0 0.0 0.1 1.3 0.3 3.1 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 1.9 1.1 0.0 0.9 0.8 0.0 5.6 6.9 0.0 0.0 0.0 0.5 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.7 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 2.0 0.1 1.3 1.9 1.1 5.6 6.9 3.1 4.9 1.9 0.9 0.2 3.2 0.0 1.0 0.1 0.0 0.3 0.0 0.0 2.9 0.4 0.1 1.0 0.0 1.8 0.0 2.1 0.1 0.2 0.0 0.0 0.0 38.9 12.3 0.6 0.4 0.0 0.0 24.8 0.2 0.1 0.6 0.0 0.6 0.0 0.2 1.1 4.8 0.1 3.3 2.8 0.0 0.0 0.0 0.0 28.6 0.0 0.2 0.0 0.0 0.0 0.3 0.0 1.5 0.9 0.0 0.0 0.0 0.0 0.3 0.2 0.0 43.0 2.4 0.0 0.8 0.2 1.5 3.5 0.0 0.0 0.0 0.3 0.1 0.0 0.0 KIF12 ENSG00000136883 "Kinesin family member 12" Q96FN5 9 114086126-114099291 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 162.3;pancreas: 85.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 105.8;Collecting duct cells: 90.1;Distal tubular cells: 80.3;Ductal cells: 43.3;Enteroendocrine cells: 64.1;Proximal enterocytes: 60.3;Proximal tubular cells: 79.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 9.6;OE19: 17.2;RPTEC TERT1: 44.8;SCLC-21H: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA020192, HPA024127" Uncertain Uncertain "Golgi apparatus,Plasma membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus, Plasma membrane" "HPA020192: AB_1852467, HPA024127: AB_1852469" "unprognostic (5.29e-2)" "unprognostic (5.03e-2)" "unprognostic (3.34e-1)" "unprognostic (1.84e-2)" "unprognostic (5.80e-2)" "unprognostic (8.38e-2)" "unprognostic (9.81e-2)" "unprognostic (4.41e-2)" "unprognostic (1.90e-1)" "unprognostic (3.98e-2)" "unprognostic (1.69e-2)" "unprognostic (3.33e-2)" "unprognostic (1.10e-2)" "unprognostic (4.51e-2)" "unprognostic (2.38e-1)" "unprognostic (2.00e-1)" "unprognostic (1.12e-2)" 0.1 0.0 2.2 1.1 2.1 0.0 25.3 0.4 3.6 11.4 2.8 7.8 25.5 4.2 1.0 0.2 8.0 24.7 0.2 2.0 0.9 162.3 27.7 1.6 0.5 0.6 1.1 0.7 85.4 0.8 0.6 1.1 1.0 7.0 4.2 0.1 3.6 4.8 0.0 1.4 16.1 0.4 0.4 0.2 11.0 2.4 1.3 1.3 31.8 0.0 0.1 0.2 0.3 0.8 0.0 4.8 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 9.6 0.2 0.0 5.2 0.0 0.6 0.0 0.2 0.1 0.2 0.0 0.9 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 6.0 0.0 0.4 0.1 17.2 0.6 0.0 0.0 0.1 44.8 0.2 6.6 0.1 0.0 0.9 0.0 0.2 4.5 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.1 0.4 3.6 2.0 0.9 0.6 1.1 1.0 0.4 1.3 0.8 0.1 0.0 4.4 0.0 1.3 0.0 0.9 0.6 0.0 0.0 20.3 10.8 0.4 105.8 0.0 90.1 0.0 0.1 0.0 7.9 80.3 43.3 7.0 8.3 1.5 0.3 64.1 0.0 0.7 11.8 9.3 0.4 14.8 15.6 0.0 0.0 0.0 10.2 0.3 0.0 0.3 22.0 0.0 0.3 0.0 14.7 0.6 0.8 0.0 0.0 1.0 0.0 0.0 0.0 0.1 5.7 21.3 0.0 0.0 2.2 60.3 79.1 0.0 0.0 0.0 0.0 0.3 3.2 7.9 0.0 0.0 0.5 0.9 0.3 28.9 0.5 KIF19 "FLJ37300, KIF19A" ENSG00000196169 "Kinesin family member 19" Q2TAC6 17 74326210-74355820 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 16.7;fallopian tube: 12.0;lymphoid tissue: 13.5" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 44.4;Enteroendocrine cells: 23.8;Hepatic stellate cells: 15.4;Intestinal goblet cells: 14.1;Plasma cells: 15.6;Respiratory ciliated cells: 57.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.1" "Lineage enriched" "Detected in single" 22 "T-cells: 2.1" "Cell line enriched" "Detected in single" 9 "SCLC-21H: 4.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043638, HPA073303" Enhanced Approved "Plasma membrane,Actin filaments,Centrosome" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" "Actin filaments, Centrosome" "HPA043638: AB_10962579, HPA073303: AB_2686593" "unprognostic (1.59e-3)" "unprognostic (1.05e-1)" "unprognostic (1.00e-1)" "unprognostic (5.37e-3)" "unprognostic (9.64e-2)" "unprognostic (1.64e-1)" "unprognostic (2.70e-2)" "unprognostic (2.81e-1)" "unprognostic (1.03e-1)" "unprognostic (9.83e-3)" "unprognostic (1.05e-3)" "unprognostic (1.14e-1)" "unprognostic (1.59e-9)" "unprognostic (5.16e-5)" "unprognostic (2.72e-1)" "unprognostic (1.67e-2)" "unprognostic (1.53e-1)" 1.4 0.1 7.5 0.4 10.3 0.2 1.2 4.0 11.4 2.2 3.5 1.7 3.0 0.3 0.0 0.5 12.0 0.4 0.3 7.2 7.4 0.2 0.9 1.9 0.1 7.5 8.0 0.2 1.1 0.0 0.3 0.0 5.9 0.9 0.6 0.1 1.0 0.2 0.4 0.6 2.3 0.4 6.2 13.5 0.7 0.6 7.7 1.0 1.9 0.6 0.1 1.6 1.5 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.2 0.0 0.3 0.6 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.4 7.5 10.3 4.0 11.4 7.2 7.4 7.5 8.0 5.9 6.2 7.7 16.7 1.3 0.0 0.0 2.0 1.3 0.0 0.4 2.5 0.0 1.1 0.1 0.0 1.6 0.0 6.3 0.0 0.0 0.0 3.5 0.8 0.0 0.0 0.5 44.4 0.2 4.2 23.8 0.4 0.0 0.0 3.1 1.0 1.1 0.7 0.0 0.0 15.4 0.1 0.1 0.0 0.1 14.1 4.1 0.6 1.6 0.3 0.0 0.3 3.6 0.0 0.1 5.7 3.1 4.0 3.7 0.0 0.1 0.0 15.6 0.3 0.2 0.0 57.6 0.3 0.0 1.8 1.3 0.2 1.6 0.0 0.1 0.0 2.5 0.2 1.9 0.2 KITLG "DFNA69, FPH2, Kitl, KL-1, MGF, SCF, SF, SLF" ENSG00000049130 "KIT ligand" P21583 12 88492793-88580851 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Cell adhesion" "Growth factor" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 83.6;Collecting duct cells: 69.9;Excitatory neurons: 46.5;Inhibitory neurons: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 299.8;SK-BR-3: 118.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070395 Approved Approved Vesicles "Intracellular and membrane" NA NA 260000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA070395: AB_2686264" "unprognostic (7.13e-2)" "unprognostic (1.90e-1)" "unprognostic (5.00e-2)" "unprognostic (2.05e-1)" "unprognostic (2.70e-1)" "unprognostic (1.93e-2)" "prognostic unfavorable (4.01e-4)" "unprognostic (2.22e-3)" "unprognostic (5.61e-3)" "unprognostic (7.89e-2)" "unprognostic (5.47e-3)" "unprognostic (5.03e-2)" "prognostic favorable (5.81e-7)" "unprognostic (7.15e-2)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (1.54e-2)" 13.2 3.9 2.3 8.2 3.5 0.3 10.6 0.2 3.1 12.9 1.2 18.7 9.6 15.1 2.8 14.3 4.0 18.5 7.0 2.9 0.3 16.0 2.3 31.6 3.3 0.0 2.5 6.0 3.7 3.7 0.2 15.0 0.0 15.1 22.6 2.3 8.8 14.8 3.1 7.1 11.6 18.8 0.3 3.5 17.4 6.3 5.2 5.1 5.9 14.4 10.4 12.3 1.3 6.2 14.3 7.1 7.1 0.9 29.0 61.5 0.0 77.6 60.1 13.5 6.4 299.8 11.0 0.0 2.2 73.3 14.9 49.5 11.5 20.1 14.2 0.1 9.5 0.0 9.5 2.6 4.4 1.9 0.0 53.5 20.6 41.6 26.8 6.3 17.9 0.0 0.0 0.3 6.8 2.5 0.2 0.0 4.8 17.7 17.9 0.0 12.6 0.0 25.0 6.5 2.3 4.8 18.5 118.9 2.2 6.5 57.2 4.3 10.0 60.7 7.4 69.0 6.8 0.0 0.0 0.0 8.4 0.2 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.5 0.2 3.1 2.9 0.3 0.0 2.5 0.0 0.3 5.2 6.2 42.5 19.2 38.3 9.4 0.5 13.5 11.2 7.5 83.6 2.7 12.2 8.1 4.4 1.5 16.5 69.9 0.0 0.1 0.0 12.0 1.9 4.4 0.4 3.1 6.8 43.1 9.5 0.0 46.5 18.2 0.1 34.5 43.3 3.4 0.0 2.1 5.0 0.4 1.2 21.9 61.4 8.5 18.3 3.2 5.7 0.9 14.0 1.9 12.4 18.7 0.0 0.3 0.0 3.0 0.6 8.7 3.0 3.8 1.4 11.2 2.3 1.4 9.8 1.2 13.1 2.2 27.2 0.2 0.5 18.5 5.3 0.0 1.0 4.4 14.7 3.2 KLB ENSG00000134962 "Klotho beta" Q86Z14 4 39406930-39451533 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adipose tissue: 19.6;liver: 17.7;pancreas: 6.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 19.6;Enteroendocrine cells: 17.4;Hepatocytes: 51.4;Intestinal goblet cells: 12.1;Spermatocytes: 39.5" "Cancer enriched" "Detected in some" 16 "liver cancer: 11.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 24 "ASC diff: 6.7;Hep G2: 25.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA021136 Uncertain NA NA 320000 "Cluster 10: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA021136: AB_1852616" "unprognostic (1.03e-2)" "unprognostic (1.61e-2)" "unprognostic (4.67e-2)" "unprognostic (2.69e-1)" "unprognostic (4.30e-2)" "unprognostic (7.02e-3)" "unprognostic (2.46e-1)" "unprognostic (9.92e-2)" "unprognostic (6.99e-3)" "unprognostic (4.51e-3)" "unprognostic (3.02e-3)" "unprognostic (8.90e-3)" "unprognostic (1.73e-1)" "unprognostic (5.03e-2)" "unprognostic (4.53e-2)" "unprognostic (3.87e-2)" "unprognostic (3.09e-2)" 19.6 0.1 0.2 0.2 0.4 0.3 3.5 0.9 0.6 0.0 0.0 0.6 0.2 0.0 0.0 0.3 0.2 0.1 0.1 0.2 0.2 0.2 17.7 1.6 0.0 0.3 0.0 0.0 6.0 0.1 0.0 0.0 0.2 0.1 0.5 0.0 0.4 0.0 0.0 0.6 0.6 0.0 0.0 0.0 1.3 2.8 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.3 0.0 0.3 0.1 0.0 6.7 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 25.7 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.3 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.6 0.0 0.0 0.2 0.4 0.9 0.6 0.2 0.2 0.3 0.0 0.2 0.0 0.1 0.3 0.6 3.2 19.6 0.0 0.7 0.5 1.1 1.4 0.0 1.6 0.7 1.1 1.2 0.0 1.2 0.0 0.0 0.4 0.5 1.6 0.0 1.1 8.5 4.4 1.5 0.4 17.4 0.0 0.5 4.3 1.5 0.5 2.6 2.2 0.0 0.2 0.4 51.4 0.2 1.7 0.6 12.1 2.0 1.0 0.6 3.2 1.5 0.4 1.8 0.0 0.1 0.4 0.0 0.5 0.2 0.9 4.8 0.7 0.0 1.2 2.1 1.1 0.4 2.3 0.0 1.2 0.5 39.5 0.9 2.0 0.9 1.4 0.8 0.5 1.1 1.1 KLC2 FLJ12387 ENSG00000174996 "Kinesin light chain 2" Q9H0B6 11 66257294-66267860 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 55.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040416, HPA040434" Approved Supported "Nucleoplasm,Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane, Cytosol" "Nucleoplasm, Mitochondria" "HPA040416: AB_10795524, HPA040434: AB_10795367" "unprognostic (1.29e-1)" "unprognostic (4.95e-3)" "unprognostic (2.99e-1)" "unprognostic (3.24e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (3.16e-4)" "unprognostic (2.43e-3)" "unprognostic (2.45e-2)" "unprognostic (6.27e-3)" "unprognostic (1.60e-1)" "unprognostic (3.49e-2)" "unprognostic (1.64e-3)" "unprognostic (4.57e-3)" "unprognostic (1.96e-2)" "unprognostic (1.81e-1)" "unprognostic (1.72e-2)" "unprognostic (8.08e-2)" 15.2 18.0 18.8 9.5 25.4 3.6 15.9 33.0 78.1 27.3 0.0 28.5 9.8 27.1 6.3 18.2 21.6 8.9 32.1 26.6 12.7 22.4 8.2 18.9 9.1 39.8 10.8 24.6 15.5 15.2 48.3 7.2 37.0 28.7 4.7 28.4 15.9 16.0 57.8 18.3 16.3 11.2 5.7 13.7 20.2 32.2 23.1 25.1 17.7 14.2 6.4 27.2 21.7 35.8 49.4 58.2 28.3 16.9 16.9 13.5 21.9 34.1 24.2 34.2 26.1 31.9 14.3 21.3 31.9 25.6 43.9 40.7 29.3 33.2 11.4 35.7 37.2 4.4 48.0 22.4 32.1 9.9 22.7 13.5 42.7 40.1 32.8 22.0 16.1 26.2 24.1 29.0 27.8 69.2 56.8 15.0 27.8 14.2 49.2 21.4 14.6 30.1 27.2 27.4 76.3 37.5 24.6 22.1 41.3 15.7 36.3 6.7 26.8 55.5 49.8 68.2 45.5 30.7 27.4 11.9 39.3 6.7 22.9 0.0 0.2 0.5 2.4 0.1 3.1 1.9 1.1 1.6 0.3 3.2 1.1 1.4 0.3 1.3 0.2 2.1 0.3 1.1 18.8 25.4 33.0 78.1 26.6 12.7 39.8 10.8 37.0 5.7 23.1 35.8 4.0 3.2 1.5 8.8 8.9 8.9 9.2 11.1 7.4 34.4 10.1 7.2 2.4 7.2 5.5 12.9 12.5 9.9 5.1 3.1 13.7 14.8 10.1 7.7 6.2 5.2 37.1 0.8 20.7 8.2 18.2 6.5 13.7 9.7 0.0 8.6 3.9 2.3 3.1 55.5 19.0 7.2 18.3 3.2 4.0 4.6 8.7 2.8 12.4 5.6 6.3 14.6 4.1 4.0 6.2 19.1 4.9 13.9 9.1 18.2 3.9 10.3 7.3 35.2 0.0 9.5 13.3 26.2 29.8 8.9 9.7 12.7 8.2 3.4 4.9 8.5 KLF4 "EZF, GKLF" ENSG00000136826 "Kruppel like factor 4" O43474 9 107484852-107490482 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 254.7" "Cell type enhanced" "Detected in many" "Adipocytes: 1054.7;Basal squamous epithelial cells: 832.1;Distal enterocytes: 789.2;Intestinal goblet cells: 710.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.0;non-classical monocyte: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 39.2;hTCEpi: 84.4;hTERT-HME1: 54.5;OE19: 47.2;U-2197: 111.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002926 Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 18: U-2197 - ECM organization" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "HPA002926: AB_1852541" "unprognostic (2.06e-1)" "unprognostic (1.42e-2)" "unprognostic (1.14e-2)" "unprognostic (2.45e-1)" "unprognostic (1.55e-1)" "unprognostic (6.58e-3)" "unprognostic (3.44e-2)" "unprognostic (6.49e-2)" "unprognostic (3.45e-1)" "unprognostic (1.29e-2)" "unprognostic (1.18e-2)" "unprognostic (1.08e-1)" "prognostic favorable (3.93e-5)" "unprognostic (2.55e-1)" "unprognostic (1.67e-1)" "unprognostic (8.13e-2)" "unprognostic (8.32e-2)" 73.5 23.9 5.1 21.0 4.7 50.5 63.7 4.0 7.8 53.2 4.6 87.3 28.4 16.0 5.6 102.1 43.0 44.3 31.0 3.7 5.1 6.2 12.4 44.8 5.6 5.0 4.7 29.0 7.0 5.7 4.9 32.4 5.0 16.7 96.0 0.8 27.5 7.6 14.2 254.7 40.5 40.6 4.1 24.1 58.0 17.8 6.0 17.0 25.2 23.2 14.5 43.9 58.9 4.0 13.3 3.9 0.6 0.1 16.6 39.2 5.2 4.4 27.6 6.7 8.1 1.0 18.0 0.0 0.6 6.9 23.7 8.7 6.1 3.9 3.0 0.0 2.2 0.0 7.5 0.3 21.6 0.0 0.0 5.0 84.4 14.0 54.5 1.5 0.6 0.2 0.6 0.0 4.1 7.3 0.0 1.4 4.1 47.2 25.2 0.3 1.6 0.2 2.3 3.7 0.4 0.2 4.0 11.8 15.2 12.7 1.3 5.4 3.5 3.6 0.1 111.5 2.1 0.2 0.1 0.0 3.4 2.6 6.8 0.0 0.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 1.0 0.2 0.0 0.1 5.1 4.7 4.0 7.8 3.7 5.1 5.0 4.7 5.0 4.1 6.0 4.0 1054.7 12.8 41.1 0.3 32.2 436.0 284.3 143.0 832.1 0.5 206.7 205.0 70.3 35.8 71.5 1.8 8.4 49.1 15.0 789.2 1.9 24.4 263.1 154.1 216.0 336.6 123.8 4.8 0.0 38.7 75.5 463.2 537.2 297.4 54.7 4.7 216.0 4.6 89.9 0.0 0.2 710.9 83.4 232.9 282.0 163.0 143.8 401.0 206.3 16.9 36.8 2.0 0.0 0.0 0.0 49.3 540.9 60.5 38.3 187.3 198.0 2.1 46.4 2.0 39.5 463.7 130.0 21.6 15.9 639.9 674.0 107.9 26.8 63.5 332.6 236.8 KLHDC10 "KIAA0265, slim" ENSG00000128607 "Kelch domain containing 10" Q6PID8 7 130070534-130135705 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020119 Approved Approved Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "HPA020119: AB_2249467" "unprognostic (2.83e-1)" "unprognostic (6.26e-2)" "unprognostic (1.13e-1)" "unprognostic (8.16e-3)" "unprognostic (3.22e-1)" "unprognostic (1.80e-2)" "unprognostic (5.55e-2)" "unprognostic (8.70e-2)" "unprognostic (7.97e-2)" "unprognostic (1.42e-2)" "unprognostic (8.69e-2)" "unprognostic (2.43e-1)" "unprognostic (1.24e-2)" "unprognostic (8.22e-2)" "unprognostic (2.04e-1)" "unprognostic (2.23e-1)" "unprognostic (1.64e-2)" 12.3 17.3 19.4 9.5 19.8 7.9 14.6 27.0 17.2 12.4 21.6 12.8 11.1 13.0 13.7 12.6 14.9 9.5 13.5 18.5 26.3 21.2 23.2 11.9 8.4 17.4 25.1 14.4 15.4 30.7 14.0 13.9 21.5 12.6 12.7 15.4 10.6 12.2 24.0 13.2 10.4 11.5 16.5 10.8 11.7 38.0 31.1 11.8 18.1 22.0 9.3 8.6 8.9 15.8 24.5 22.5 15.3 83.8 19.9 21.8 7.0 22.9 17.5 17.1 17.7 12.4 18.3 20.7 15.8 21.2 28.4 18.8 24.6 14.6 21.4 16.9 14.8 12.2 24.7 14.6 15.6 22.5 14.4 13.8 24.8 26.2 16.4 21.2 24.4 14.2 59.9 12.7 19.4 20.7 19.5 21.9 2.6 18.0 14.6 15.8 28.6 15.1 23.5 16.7 24.6 19.7 36.8 65.2 18.5 18.5 15.9 16.6 27.7 21.8 9.5 29.5 27.6 16.7 23.6 19.2 45.7 21.4 30.0 0.0 0.4 0.5 0.6 0.6 0.5 0.4 0.4 0.7 0.5 1.1 0.3 0.7 0.4 0.1 0.5 0.4 0.9 0.1 19.4 19.8 27.0 17.2 18.5 26.3 17.4 25.1 21.5 16.5 31.1 15.8 18.6 19.2 20.2 53.8 9.7 23.2 7.8 13.6 14.2 20.1 31.0 20.1 23.1 30.0 19.7 35.0 39.6 11.3 12.6 18.2 3.9 18.3 66.7 31.2 24.9 19.0 19.9 18.7 85.7 23.8 9.6 22.2 13.3 18.4 6.3 19.6 37.9 42.3 12.2 35.3 86.1 15.8 20.3 23.0 12.8 17.4 15.2 11.7 17.8 72.1 15.5 18.4 7.2 82.4 59.9 20.5 9.2 24.5 9.8 13.0 16.2 27.5 27.2 22.1 0.0 30.6 14.7 36.2 6.3 17.5 29.1 11.2 9.6 22.7 20.4 12.2 KLHDC2 "HCLP-1, LCP" ENSG00000165516 "Kelch domain containing 2" Q9Y2U9 14 49768130-49786385 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000628 Approved Supported "Nucleoplasm,Nuclear membrane,Nuclear bodies" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear membrane" "Nuclear bodies" "HPA000628: AB_2666051" "unprognostic (2.65e-1)" "unprognostic (8.29e-2)" "unprognostic (1.30e-2)" "unprognostic (9.01e-2)" "unprognostic (2.57e-2)" "unprognostic (5.52e-3)" "unprognostic (4.54e-2)" "unprognostic (9.72e-3)" "unprognostic (7.43e-2)" "unprognostic (1.24e-1)" "unprognostic (4.81e-3)" "unprognostic (6.77e-3)" "prognostic favorable (2.75e-10)" "unprognostic (2.20e-2)" "unprognostic (2.08e-1)" "unprognostic (1.32e-2)" "unprognostic (9.34e-2)" 21.5 22.3 12.8 8.6 13.3 10.1 19.6 13.7 16.1 18.8 15.0 23.8 18.4 20.7 14.8 15.0 17.0 13.8 38.0 14.4 14.0 34.1 49.1 14.5 10.9 12.4 12.3 25.1 30.3 16.8 17.7 12.7 13.9 18.5 18.0 23.9 20.1 20.1 53.0 18.8 21.6 14.1 13.3 12.3 24.4 23.3 12.6 15.2 28.2 38.2 10.5 22.3 16.2 14.9 14.7 12.2 22.5 11.0 31.7 27.5 23.7 15.0 28.8 18.8 19.0 7.1 19.6 29.1 20.4 27.4 10.8 12.8 13.9 13.9 15.9 20.1 14.7 9.1 8.6 17.0 23.1 19.6 7.8 28.6 23.5 8.6 16.9 23.1 17.4 24.6 11.8 21.5 15.1 17.3 20.1 8.6 16.6 17.0 34.8 15.3 24.0 18.1 8.6 31.2 27.4 22.0 25.1 46.4 17.1 17.2 17.8 7.4 14.9 17.2 13.3 13.7 7.8 29.0 19.7 17.1 9.7 10.0 9.2 12.3 9.1 19.9 11.1 6.1 13.8 18.2 16.8 17.4 9.0 19.0 23.5 15.8 8.4 16.8 5.8 6.8 18.0 12.3 12.8 13.3 13.7 16.1 14.4 14.0 12.4 12.3 13.9 13.3 12.6 14.9 40.6 41.7 52.4 30.3 42.1 48.9 53.5 64.8 53.5 65.1 48.6 40.9 9.3 77.2 53.9 47.8 50.1 102.5 40.7 68.9 107.6 59.8 96.8 44.8 41.9 36.4 57.2 47.8 30.6 85.8 68.6 51.2 67.2 38.7 30.4 62.8 45.3 91.8 33.2 65.6 35.4 75.3 63.1 28.7 33.6 27.1 81.4 26.5 39.2 18.7 36.3 73.9 54.6 28.1 33.1 54.8 78.9 77.5 74.5 53.9 143.9 170.1 27.8 98.1 65.7 46.3 90.5 238.7 93.2 42.7 66.3 82.4 44.9 54.7 78.9 55.5 KLRB1 "CD161, CLEC5B, hNKR-P1A, NKR, NKR-P1, NKR-P1A" ENSG00000111796 "Killer cell lectin like receptor B1" Q12918 12 9594551-9607916 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.4;lymphoid tissue: 36.4" "Group enriched" "Detected in many" 9 "dendritic cells: 642.3;NK-cells: 1855.8;T-cells: 790.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in all" "MAIT T-cell: 2177.1" "Group enriched" "Detected in all" 140 "NK-cells: 756.7;T-cells: 2177.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA039113 Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm Cytosol "HPA039113: AB_10674979" "prognostic favorable (3.51e-5)" "unprognostic (1.23e-3)" "unprognostic (7.03e-3)" "prognostic favorable (1.42e-5)" "unprognostic (1.69e-1)" "prognostic favorable (6.99e-5)" "unprognostic (1.54e-3)" "unprognostic (7.15e-3)" "unprognostic (4.12e-1)" "unprognostic (8.23e-3)" "unprognostic (3.57e-2)" "unprognostic (1.65e-1)" "unprognostic (1.17e-2)" "unprognostic (2.45e-1)" "unprognostic (1.34e-1)" "prognostic favorable (5.61e-4)" "unprognostic (1.17e-2)" 3.1 1.7 0.7 17.8 0.8 47.4 5.1 0.3 0.8 4.2 0.2 7.7 10.7 1.6 1.4 3.2 1.5 10.7 0.7 0.6 0.7 1.4 11.3 6.7 20.1 0.6 0.6 1.0 0.4 0.2 0.3 1.4 0.6 2.1 8.1 0.1 0.8 1.0 0.7 0.8 20.1 1.6 0.6 28.9 10.1 0.6 0.6 5.7 1.3 0.9 36.4 10.6 1.3 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.1 0.3 0.0 0.4 0.2 9.5 2.2 1.1 519.7 2.1 2177.1 1.6 307.4 346.1 1.9 1.5 17.1 98.0 10.5 756.7 3.6 3.9 77.9 285.3 0.7 0.8 0.3 0.8 0.6 0.7 0.6 0.6 0.6 0.6 0.6 0.8 6.1 0.0 8.9 0.0 19.0 9.7 0.9 0.0 1.2 0.0 5.2 2.5 1.0 4.3 1.3 0.0 0.0 0.4 642.3 1.7 0.0 0.6 0.0 1.9 1.5 6.2 0.0 118.1 0.4 0.0 0.1 7.9 12.2 2.4 0.0 0.0 45.3 10.1 0.9 0.0 0.6 1.0 0.0 36.2 15.8 0.0 0.0 13.2 24.9 0.0 28.1 0.0 1855.8 2.5 0.1 0.0 3.3 0.0 23.0 1.1 0.9 2.0 0.0 0.0 0.0 1.6 4.1 0.0 0.1 1.2 8.8 1.0 790.5 0.0 2.0 1.3 KLRC1 "CD159a, NKG2, NKG2-A, NKG2-B" ENSG00000134545 "Killer cell lectin like receptor C1" P26715 12 10442264-10454685 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 6.7" "Group enriched" "Detected in some" 8 "dendritic cells: 104.2;NK-cells: 254.3;T-cells: 100.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "gdT-cell: 229.2;NK-cell: 367.6" "Group enriched" "Detected in many" 46 "NK-cells: 367.6;T-cells: 229.2" "Cell line enhanced" "Detected in some" "HeLa: 5.6;Karpas-707: 1.9" HPA058052 Approved "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA058052: AB_2683589" "unprognostic (8.17e-3)" "unprognostic (2.13e-2)" "unprognostic (1.48e-2)" "unprognostic (4.58e-7)" "unprognostic (3.57e-1)" "unprognostic (1.17e-2)" "unprognostic (1.05e-1)" "unprognostic (3.68e-2)" "unprognostic (3.73e-4)" "unprognostic (4.13e-2)" "unprognostic (6.49e-2)" "unprognostic (2.54e-1)" "unprognostic (1.18e-4)" "unprognostic (1.88e-1)" "unprognostic (3.23e-1)" "unprognostic (2.45e-1)" "unprognostic (1.92e-3)" 0.7 0.5 0.8 2.2 0.8 5.3 2.0 0.6 1.4 0.7 0.4 1.8 1.4 3.1 1.5 1.4 0.9 2.0 0.7 1.0 1.6 0.3 1.8 3.3 3.1 1.4 1.4 0.7 0.8 0.3 0.3 2.2 1.0 0.7 2.0 1.2 1.2 0.4 0.4 1.0 2.6 0.9 1.2 6.7 4.3 0.9 1.8 1.1 0.7 0.0 2.5 1.0 0.6 2.0 0.2 0.8 0.0 0.0 0.2 0.2 0.4 0.0 0.0 0.4 0.8 0.0 0.6 0.1 0.0 0.2 1.6 0.1 0.3 1.4 0.5 0.4 0.2 1.0 5.6 0.0 0.0 0.3 0.1 0.5 0.0 0.1 0.0 0.0 0.4 0.3 0.6 1.9 0.4 0.0 0.1 1.4 0.0 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.2 0.0 0.4 0.0 0.1 1.7 0.1 0.0 1.3 0.2 0.0 0.0 0.1 0.0 0.0 0.3 1.0 0.4 0.0 1.9 0.3 0.2 229.2 0.3 29.1 0.6 0.1 40.1 0.3 0.2 0.3 33.2 6.4 367.6 0.6 0.4 0.1 28.6 0.8 0.8 0.6 1.4 1.0 1.6 1.4 1.4 1.0 1.2 1.8 2.0 1.2 0.0 0.6 0.0 1.3 0.1 0.3 0.0 0.0 0.0 0.9 1.3 0.5 1.5 0.0 0.0 0.0 0.1 104.2 0.8 0.0 0.1 1.3 0.3 0.4 0.4 1.8 11.2 0.2 0.0 0.0 0.6 3.1 0.4 0.0 0.0 3.9 0.9 0.1 1.7 0.1 2.8 0.0 4.0 0.4 0.4 0.6 2.0 5.4 0.0 1.4 0.0 254.3 1.0 0.0 0.0 1.2 1.2 17.6 0.1 0.6 0.6 0.0 2.0 0.0 0.1 0.8 1.1 0.6 0.5 0.1 0.1 100.2 0.0 0.5 0.4 KLRD1 CD94 ENSG00000134539 "Killer cell lectin like receptor D1" Q13241 12 10226058-10329608 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 17.0" "Cell type enhanced" "Detected in many" "dendritic cells: 740.2;NK-cells: 1316.2;T-cells: 324.9" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "gdT-cell: 512.6;memory CD8 T-cell: 217.7;naive CD8 T-cell: 218.7;NK-cell: 737.5" "Group enriched" "Detected in many" 68 "NK-cells: 737.5;T-cells: 512.6" "Low cell line specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" HPA069688 Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" "HPA069688: AB_2686170" "unprognostic (3.75e-2)" "unprognostic (2.15e-3)" "unprognostic (4.95e-2)" "unprognostic (2.48e-3)" "unprognostic (2.13e-2)" "unprognostic (2.60e-3)" "unprognostic (2.26e-2)" "unprognostic (1.13e-1)" "unprognostic (8.94e-3)" "unprognostic (4.53e-3)" "unprognostic (8.78e-2)" "unprognostic (2.97e-2)" "unprognostic (1.47e-3)" "unprognostic (1.78e-1)" "unprognostic (3.07e-1)" "unprognostic (3.06e-1)" "unprognostic (1.37e-2)" 1.6 1.4 1.5 2.8 1.1 8.4 1.8 2.1 2.1 1.2 0.0 1.6 1.8 1.2 1.5 1.3 1.1 1.6 1.1 1.6 0.7 0.8 4.1 4.7 6.8 0.4 0.2 1.1 2.2 0.5 4.6 1.3 0.4 0.6 0.9 1.3 1.3 0.6 1.2 0.9 3.4 0.7 0.1 17.0 2.1 1.2 1.0 0.5 1.2 0.2 4.0 2.1 0.8 3.0 0.2 0.1 0.2 0.4 0.4 0.2 0.2 0.7 0.0 0.0 0.2 0.4 0.3 0.3 0.2 0.3 0.2 0.3 0.0 0.2 0.0 0.5 0.5 0.4 0.7 0.1 0.5 0.3 0.2 0.1 0.5 0.1 0.3 0.3 0.1 0.3 0.3 1.2 0.0 0.5 0.3 0.3 0.3 0.2 0.4 0.1 0.4 0.3 0.2 0.3 0.6 0.2 0.2 0.6 0.1 0.9 0.2 0.6 0.3 0.5 0.9 0.4 0.1 0.5 0.5 0.3 0.7 0.2 0.4 1.7 0.8 1.1 512.6 2.0 58.1 0.8 3.5 217.7 1.6 0.8 1.3 218.7 9.2 737.5 1.5 2.1 1.3 163.0 1.5 1.1 2.1 2.1 1.6 0.7 0.4 0.2 0.4 0.1 1.0 3.0 7.4 0.0 10.5 1.3 5.8 0.5 1.2 0.2 0.6 0.7 1.7 1.0 2.7 7.2 1.9 0.0 6.2 1.8 740.2 0.4 0.0 0.6 9.0 1.1 1.2 7.7 0.0 24.0 3.1 0.0 1.0 4.5 10.7 1.8 2.5 0.4 15.0 4.3 0.7 1.7 2.0 0.2 0.0 18.3 1.2 12.6 0.3 7.0 5.4 4.7 5.1 0.3 1316.2 1.5 1.8 0.0 0.0 0.7 91.0 1.3 0.2 1.1 1.5 1.0 0.0 2.2 1.7 1.9 3.5 0.3 0.6 0.8 324.9 0.0 0.3 1.4 KLRK1 "CD314, D12S2489E, KLR, NKG2-D, NKG2D" ENSG00000213809 "Killer cell lectin like receptor K1" P26718 12 10372353-10391874 "Cancer-related genes, CD markers, Predicted membrane proteins, Transporters" "Adaptive immunity, Differentiation, Immunity, Innate immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.1;lymphoid tissue: 42.9" "Cell type enhanced" "Detected in some" "dendritic cells: 7.2;NK-cells: 6.2;Plasma cells: 4.5;T-cells: 22.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 40 "gdT-cell: 287.4;MAIT T-cell: 111.5;memory CD8 T-cell: 261.2;naive CD8 T-cell: 258.8;NK-cell: 335.8" "Group enriched" "Detected in all" 50 "NK-cells: 335.8;T-cells: 287.4" "Cell line enriched" "Detected in some" 9 "U-698: 64.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB021896, HPA068877" Enhanced Supported "Plasma membrane" NA NA 47000 "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB021896: , HPA068877: AB_2686052" "unprognostic (3.34e-4)" "unprognostic (2.65e-4)" "unprognostic (3.25e-1)" "unprognostic (2.59e-2)" "unprognostic (1.53e-1)" "unprognostic (1.01e-5)" "unprognostic (5.61e-4)" "unprognostic (1.00e-3)" "unprognostic (1.33e-1)" "unprognostic (9.22e-2)" "unprognostic (1.28e-2)" "unprognostic (2.10e-2)" "unprognostic (6.56e-10)" "unprognostic (1.24e-2)" "unprognostic (6.32e-2)" "unprognostic (7.59e-2)" "unprognostic (7.08e-10)" 5.5 2.1 1.7 12.6 1.9 22.1 4.1 1.7 2.8 2.2 1.2 3.9 4.7 2.5 2.3 2.2 2.8 7.3 1.8 1.7 2.0 2.0 5.5 12.1 37.0 2.0 1.7 2.4 1.1 0.5 1.1 1.4 1.8 2.5 4.5 0.4 4.4 0.9 0.8 1.3 12.2 1.8 1.7 42.9 7.2 2.5 1.7 9.9 3.6 1.5 19.0 4.5 3.2 2.4 0.3 0.0 0.7 2.8 0.2 7.1 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 2.6 0.0 0.0 0.2 0.2 0.0 0.7 1.4 0.0 0.3 0.0 0.4 0.2 0.6 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.8 0.3 0.1 0.1 0.0 2.0 0.2 0.3 0.1 0.1 0.8 0.0 0.0 0.0 0.0 64.2 0.2 0.0 0.3 0.4 0.5 0.2 287.4 0.6 111.5 6.2 1.7 261.2 0.6 6.1 2.3 258.8 4.8 335.8 1.3 1.9 0.7 127.9 1.7 1.9 1.7 2.8 1.7 2.0 2.0 1.7 1.8 1.7 1.7 2.4 0.0 0.0 1.3 0.0 2.4 0.0 0.1 0.2 1.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.2 0.0 0.5 1.8 0.0 0.5 0.0 6.2 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 22.2 1.0 0.0 0.0 KNG1 "BDK, BK, KNG" ENSG00000113889 "Kininogen 1" P01042 3 186717348-186744410 "Disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis, Inflammatory response" "Protease inhibitor, Thiol protease inhibitor, Vasoactive, Vasodilator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "liver: 3195.2" "Group enriched" "Detected in some" 25 "Distal tubular cells: 655.4;Hepatocytes: 1816.9" "Cancer enriched" "Detected in some" 126 "liver cancer: 608.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.6;Hep G2: 1.7;RH-30: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001616, HPA001645, CAB009809" Enhanced "Secreted to blood" NA NA 90000000000 47000000000 "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "CAB009809: AB_2134781, HPA001616: AB_1079216, HPA001645: AB_1079215" "unprognostic (3.88e-1)" "unprognostic (1.63e-1)" "unprognostic (2.82e-1)" "unprognostic (3.27e-1)" "unprognostic (8.30e-3)" "unprognostic (2.04e-1)" "prognostic favorable (1.28e-6)" "unprognostic (1.29e-2)" "unprognostic (1.10e-1)" "unprognostic (1.97e-2)" "unprognostic (9.96e-2)" "unprognostic (1.65e-1)" "unprognostic (3.45e-3)" "unprognostic (5.20e-2)" "unprognostic (2.46e-1)" "unprognostic (4.52e-2)" 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 464.1 3195.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.4 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.9 0.1 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.7 5.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 48.6 0.0 33.1 0.0 0.0 0.0 1.8 655.4 0.0 0.4 0.0 0.0 1.5 0.0 40.2 1.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 30.0 1816.9 0.1 0.0 0.8 0.1 0.0 47.2 0.0 0.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.0 0.5 0.1 1.1 0.0 0.0 0.0 0.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 2.7 0.0 0.1 0.1 KSR1 "KSR, RSU2" ENSG00000141068 "Kinase suppressor of ras 1" Q8IVT5 17 27456470-27626438 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 101.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 73.0;Glandular and luminal cells: 50.3;Inhibitory neurons: 50.2;Oligodendrocyte precursor cells: 53.3;Oligodendrocytes: 49.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 393.5;HEL: 140.5;HMC-1: 93.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009623, HPA011215, HPA011878" Uncertain Supported Vesicles,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" Cytosol Vesicles "CAB009623: AB_2265455, HPA011215: AB_1852649, HPA011878: " "unprognostic (2.03e-2)" "unprognostic (2.74e-1)" "unprognostic (2.60e-1)" "unprognostic (3.48e-3)" "unprognostic (2.90e-1)" "unprognostic (6.98e-2)" "unprognostic (1.92e-5)" "unprognostic (8.36e-3)" "unprognostic (1.32e-1)" "unprognostic (3.15e-2)" "unprognostic (1.12e-3)" "unprognostic (1.65e-1)" "prognostic unfavorable (6.54e-4)" "unprognostic (1.00e-1)" "unprognostic (7.55e-2)" "unprognostic (1.74e-2)" "unprognostic (9.61e-2)" 22.6 17.5 19.6 19.9 22.0 16.7 15.6 17.4 35.8 36.9 13.2 13.1 8.1 26.5 9.9 29.8 20.8 21.4 13.6 33.1 19.3 40.7 6.5 26.2 14.3 28.6 20.2 26.4 101.4 7.3 15.1 44.9 23.0 15.6 8.5 19.4 8.4 18.5 30.0 21.6 15.2 20.0 17.5 22.5 9.3 25.3 22.9 11.6 31.0 14.0 14.6 14.6 23.1 26.7 4.6 18.1 11.1 5.8 9.2 6.5 64.7 4.2 9.1 6.2 7.2 55.0 0.8 4.4 9.5 8.0 40.8 2.8 11.0 2.5 3.7 393.5 12.1 140.5 19.3 23.0 16.0 1.8 93.0 8.1 4.0 17.8 0.5 25.3 34.8 6.1 75.0 0.5 3.6 4.4 2.1 5.4 8.3 4.0 3.2 9.1 61.5 3.2 25.1 3.3 17.1 11.3 22.3 5.1 6.0 29.4 0.7 7.5 32.5 1.8 8.2 5.1 3.0 0.5 0.1 0.1 1.8 7.9 10.5 0.0 1.0 3.8 0.3 2.1 0.3 0.4 0.1 0.2 0.5 0.1 0.1 0.1 1.1 0.9 1.1 0.0 0.5 0.4 19.6 22.0 17.4 35.8 33.1 19.3 28.6 20.2 23.0 17.5 22.9 26.7 19.7 6.4 3.4 33.6 4.1 3.1 3.6 3.1 1.8 11.8 1.9 2.3 1.2 1.5 11.9 14.7 73.0 19.2 4.9 7.1 3.9 2.0 33.4 24.0 21.6 9.1 6.6 0.4 26.2 5.3 21.0 8.2 3.6 50.3 0.0 10.8 11.7 1.3 6.7 10.1 50.2 2.2 0.0 8.3 6.9 47.7 1.5 9.0 8.8 27.2 10.4 5.7 4.1 53.3 49.2 2.1 7.1 2.2 2.8 1.6 6.7 3.2 14.9 25.8 0.0 5.3 4.8 2.6 6.1 11.3 6.0 19.4 5.7 8.4 1.2 6.2 KTN1 "CG1, KIAA0004, KNT" ENSG00000126777 "Kinectin 1" Q86UP2 14 55559072-55701526 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003178, CAB015331, HPA017876" Enhanced Enhanced "Endoplasmic reticulum" NA NA 55000 "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Endoplasmic reticulum" "CAB015331: , HPA003178: AB_1079218, HPA017876: AB_1852652" "unprognostic (7.00e-3)" "unprognostic (2.99e-2)" "unprognostic (8.60e-2)" "unprognostic (5.50e-2)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.83e-5)" "prognostic unfavorable (3.76e-4)" "unprognostic (1.75e-1)" "unprognostic (1.21e-2)" "unprognostic (1.01e-1)" "unprognostic (9.08e-2)" "unprognostic (8.72e-2)" "prognostic favorable (1.01e-6)" "unprognostic (1.27e-1)" "unprognostic (2.75e-1)" "unprognostic (1.30e-1)" "unprognostic (1.04e-1)" 81.6 77.7 90.8 52.8 98.9 36.1 81.6 92.8 106.3 61.4 165.0 97.4 43.4 58.1 97.1 72.7 53.2 58.6 134.6 81.0 94.2 104.0 106.6 67.0 61.8 100.2 95.3 63.9 67.2 143.0 67.4 69.4 100.7 77.5 90.8 127.9 73.5 73.5 378.2 137.6 53.2 60.3 95.2 53.4 61.1 145.1 99.4 54.7 107.7 281.6 61.0 113.1 55.2 110.3 200.5 133.4 100.3 106.5 132.8 127.3 140.2 159.7 127.3 97.2 85.2 89.4 233.9 152.8 213.4 166.7 102.7 347.2 122.5 138.2 162.7 251.9 65.2 109.1 223.0 174.4 126.3 160.3 83.3 119.1 124.6 122.1 208.4 208.3 161.9 122.2 107.4 88.1 189.0 154.6 141.3 95.0 76.8 91.1 194.3 109.6 258.2 73.5 244.8 307.0 122.4 100.0 245.8 113.2 143.2 201.7 115.3 101.7 230.0 193.9 250.4 100.0 151.2 38.9 55.9 110.4 229.4 93.4 109.5 117.0 42.7 48.0 56.2 40.3 54.7 95.6 69.4 65.8 44.0 106.6 71.1 62.1 29.6 64.9 52.6 185.8 48.4 16.0 90.8 98.9 92.8 106.3 81.0 94.2 100.2 95.3 100.7 95.2 99.4 110.3 363.1 307.7 239.8 72.5 171.7 654.5 285.8 215.6 270.9 206.5 460.6 348.7 852.7 270.2 214.7 428.6 360.7 155.1 194.9 575.2 31.3 249.7 721.9 351.3 186.6 345.0 224.0 165.3 93.9 304.0 199.1 211.9 95.3 298.1 134.9 384.5 295.9 401.7 116.8 326.4 112.1 226.4 207.5 181.3 261.6 377.9 248.5 168.9 172.5 104.9 194.3 449.2 142.2 90.0 139.8 341.2 325.7 441.6 184.6 283.5 152.6 109.3 319.3 400.9 335.2 333.5 292.1 694.3 386.4 217.8 723.0 164.7 168.3 162.4 282.4 328.0 LAMA4 LAMA3 ENSG00000112769 "Laminin subunit alpha 4" Q16363 6 112107931-112254939 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 115.7;Early spermatids: 114.7;Extravillous trophoblasts: 119.1;Fibroblasts: 149.2;Leydig cells: 166.5;Microglial cells: 124.6;Oligodendrocyte precursor cells: 160.4;Theca cells: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 330.5;ASC TERT1: 512.5;HSkMC: 405.5;hTERT-RPE1: 256.0;HUVEC TERT2: 441.3;TIME: 404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015693, CAB078156" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 320000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "CAB078156: AB_2665814, HPA015693: AB_1852687" "unprognostic (1.87e-2)" "unprognostic (6.48e-2)" "unprognostic (8.37e-2)" "unprognostic (2.39e-2)" "unprognostic (1.04e-1)" "unprognostic (1.15e-1)" "unprognostic (2.52e-2)" "unprognostic (5.07e-2)" "unprognostic (4.59e-2)" "unprognostic (2.93e-2)" "unprognostic (9.06e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (4.40e-3)" "unprognostic (1.85e-1)" "unprognostic (2.80e-2)" "unprognostic (1.15e-2)" 116.2 9.4 17.6 34.0 17.1 0.5 59.9 11.7 12.9 77.0 12.6 82.6 17.2 77.5 18.5 35.6 115.2 37.3 51.2 12.3 17.9 9.9 4.4 80.8 11.5 12.7 16.3 23.2 4.9 8.6 13.6 68.0 14.7 35.4 34.0 1.3 38.4 40.7 10.6 17.7 34.5 107.8 11.4 1.5 36.7 18.7 22.6 5.0 23.2 18.6 8.9 65.1 40.3 11.4 0.3 0.1 18.8 0.6 330.5 512.5 0.3 91.4 55.8 8.9 1.4 0.0 36.1 0.0 58.0 154.9 19.8 0.3 4.0 0.6 1.5 0.3 46.4 0.0 44.4 0.0 69.6 0.1 0.3 405.5 0.1 64.9 0.2 256.0 441.3 0.0 0.4 0.4 1.7 0.0 0.1 0.3 1.1 0.0 15.1 0.2 0.2 0.3 134.0 2.8 0.4 2.1 14.2 0.4 68.5 1.5 0.4 0.2 404.9 145.1 7.6 160.6 29.1 0.0 0.3 0.3 33.5 0.2 191.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 17.1 11.7 12.9 12.3 17.9 12.7 16.3 14.7 11.4 22.6 11.4 115.7 3.2 4.5 45.4 0.1 22.7 1.4 2.9 8.6 1.6 5.4 9.4 53.3 2.8 10.4 3.7 0.0 1.0 0.6 0.0 3.9 0.7 114.7 6.2 24.8 103.5 0.0 2.7 27.4 0.7 119.1 149.2 3.6 10.5 1.3 3.5 36.0 35.3 3.0 0.0 6.3 0.8 20.3 1.6 20.8 47.0 166.5 2.0 56.9 124.6 0.6 0.0 0.0 160.4 2.0 0.7 0.0 81.3 1.5 1.5 0.0 0.1 1.7 0.5 65.7 5.4 98.2 1.3 1.2 5.0 18.6 3.0 2.7 117.4 0.0 12.9 LAMC2 "BM600-100kDa, EBR2, EBR2A, kalinin-105kDa, LAMB2T, LAMNB2, nicein-100kDa" ENSG00000058085 "Laminin subunit gamma 2" Q13753 1 183186238-183245127 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 39.3" "Cell type enriched" "Detected in many" 5 "Pancreatic endocrine cells: 1531.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 231.3" "Region enhanced" "Detected in some" "cerebellum: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 574.7;CAPAN-2: 501.6;HBEC3-KT: 2492.2;hTERT-HME1: 1487.5;RPTEC TERT1: 579.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004257, HPA024638, HPA046539, CAB078165" Enhanced Uncertain "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" No No 130000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum, Golgi apparatus" "CAB004257: AB_627873, CAB078165: AB_2665800, HPA024638: AB_1852689, HPA046539: " "unprognostic (7.27e-3)" "unprognostic (7.21e-3)" "unprognostic (3.24e-1)" "unprognostic (6.20e-3)" "unprognostic (9.43e-2)" "unprognostic (4.94e-3)" "unprognostic (4.12e-2)" "prognostic unfavorable (4.20e-6)" "unprognostic (1.25e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (7.11e-5)" "unprognostic (2.77e-1)" "unprognostic (7.24e-2)" "unprognostic (1.47e-1)" "unprognostic (2.18e-1)" "unprognostic (3.18e-1)" "unprognostic (1.26e-1)" 3.5 0.1 0.2 16.2 1.9 0.1 20.9 2.6 0.6 15.1 0.2 12.1 2.6 12.3 2.1 7.7 34.9 13.0 3.0 0.2 0.2 13.8 0.7 24.9 8.0 0.0 0.1 1.0 3.3 0.0 4.2 10.9 0.1 5.4 12.9 0.1 12.9 6.1 1.7 17.5 15.0 3.3 0.0 0.9 14.9 2.8 0.1 11.3 18.5 2.3 12.3 39.3 6.3 0.2 574.7 25.4 0.0 0.7 4.9 11.9 40.2 4.3 4.7 2.1 0.7 41.4 501.6 0.0 207.9 1.4 16.4 252.4 0.1 2492.2 2.7 0.7 0.2 0.0 0.5 0.1 1.2 0.0 0.2 6.1 189.7 6.0 1487.5 2.3 32.6 0.0 0.0 0.2 2.5 1.1 0.0 0.1 4.5 206.7 35.2 0.1 1.2 0.0 579.4 147.1 30.5 0.1 14.7 0.4 0.9 14.9 2.0 2.7 3.8 2.2 30.2 15.0 7.8 0.9 0.7 0.7 4.1 0.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.9 2.6 0.6 0.2 0.2 0.0 0.1 0.1 0.0 0.1 0.2 0.5 218.0 17.8 0.0 0.2 86.3 227.1 232.7 105.3 0.0 8.2 26.2 2.3 10.0 56.8 23.9 0.0 30.7 0.4 74.4 0.0 183.4 19.6 68.9 3.6 7.8 9.0 0.0 0.4 94.0 11.7 17.2 59.7 97.4 0.0 0.0 0.0 0.0 2.5 0.0 0.3 34.1 14.2 0.0 4.9 11.8 3.4 3.1 8.8 1.0 2.6 0.0 0.0 0.0 0.3 1531.1 91.2 0.4 0.3 302.0 16.7 0.2 69.3 0.0 0.0 3.4 9.6 3.6 1.0 60.3 29.7 83.3 5.3 0.1 15.3 169.9 LBX2 ENSG00000179528 "Ladybird homeobox 2" Q6XYB7 2 74497517-74503316 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 5.3;liver: 8.7;stomach 1: 3.2" "Cell type enhanced" "Detected in some" "Hepatocytes: 3.7;Proximal tubular cells: 7.5;Sertoli cells: 6.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 10.5;Hep G2: 22.1;SK-MEL-30: 10.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cerebellum: 1.9;olfactory bulb: 1.0" HPA044257 Uncertain Approved Nucleoplasm,Midbody Yes No "Cluster 14: Monocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Midbody "HPA044257: AB_2678880" "unprognostic (5.24e-2)" "unprognostic (7.97e-2)" "unprognostic (2.35e-5)" "unprognostic (8.22e-4)" "unprognostic (2.95e-1)" "unprognostic (2.94e-1)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (2.02e-1)" "unprognostic (2.76e-2)" "unprognostic (1.85e-1)" "unprognostic (3.25e-2)" "unprognostic (1.43e-5)" "unprognostic (5.77e-2)" "unprognostic (1.69e-1)" "unprognostic (1.78e-1)" "unprognostic (1.87e-2)" 1.3 0.3 0.3 0.4 0.3 0.4 0.6 0.9 0.4 0.4 0.0 1.1 5.3 0.3 0.2 0.2 0.2 0.4 0.3 0.1 0.2 1.3 8.7 0.5 0.4 0.5 0.2 0.1 0.7 0.1 0.0 0.5 0.5 0.3 0.1 0.1 0.5 0.3 0.4 0.9 4.8 0.2 0.1 1.1 3.2 0.1 0.4 0.0 0.3 0.0 0.1 0.3 0.2 1.3 4.4 1.6 0.0 0.1 2.0 1.5 7.1 0.3 0.2 0.4 0.4 10.5 6.2 0.2 1.7 0.8 0.6 1.7 0.0 0.3 0.0 9.0 1.8 4.7 0.7 22.1 1.4 0.3 3.0 1.9 1.6 1.6 0.3 0.2 1.8 0.1 3.1 2.2 0.3 2.3 0.1 0.7 0.4 1.7 0.2 0.4 0.4 0.2 0.2 1.4 0.2 1.1 2.6 0.4 10.1 0.1 0.2 0.3 4.1 1.5 6.6 8.1 0.2 2.9 2.3 0.2 1.5 0.8 4.8 0.5 1.5 0.1 0.3 0.8 0.2 0.0 0.1 0.4 0.8 0.0 0.1 0.2 0.6 1.1 2.2 0.2 0.0 0.7 0.3 0.3 0.9 0.4 0.1 0.2 0.5 0.2 0.5 0.1 0.4 1.3 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.7 0.5 0.7 1.5 0.5 1.8 0.0 0.3 0.5 0.9 0.0 0.6 0.0 0.4 0.5 1.0 2.4 0.4 0.0 0.6 0.5 1.3 1.1 0.2 0.0 0.0 1.4 3.7 1.1 0.0 0.0 0.2 0.0 0.6 0.3 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 0.0 2.4 7.5 0.7 0.0 6.6 0.0 0.9 0.4 0.1 0.3 0.1 0.5 0.5 0.2 1.0 0.1 LCP2 "SLP-76, SLP76" ENSG00000043462 "Lymphocyte cytosolic protein 2" Q13094 5 170246233-170297815 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 163.9;lymphoid tissue: 115.1" "Cell type enhanced" "Detected in many" "granulocytes: 129.6;Kupffer cells: 154.4;Macrophages: 158.2;NK-cells: 91.6;T-cells: 104.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 147.0;HL-60: 152.5;HMC-1: 375.9;Karpas-707: 80.4;MOLT-4: 91.4;THP-1: 80.8;U-937: 99.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004574, HPA036396, HPA036397" Enhanced NA NA 2900000 "Cluster 52: Eosinophils - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "CAB004574: AB_628259, HPA036396: AB_10671840, HPA036397: AB_10670436" "unprognostic (1.33e-2)" "unprognostic (3.88e-2)" "unprognostic (7.52e-3)" "prognostic favorable (5.08e-4)" "unprognostic (1.43e-1)" "unprognostic (1.30e-2)" "unprognostic (2.03e-1)" "unprognostic (8.84e-2)" "unprognostic (1.44e-1)" "unprognostic (4.87e-2)" "unprognostic (1.37e-1)" "unprognostic (3.10e-1)" "prognostic unfavorable (6.22e-5)" "unprognostic (1.87e-1)" "unprognostic (3.56e-2)" "unprognostic (1.71e-2)" "unprognostic (1.07e-1)" 23.0 14.1 5.0 75.7 5.7 163.9 8.4 5.9 22.9 10.3 6.3 14.6 15.8 8.2 4.9 9.6 6.8 28.6 5.7 5.1 6.9 5.6 26.3 31.5 77.5 12.2 8.4 3.7 7.7 3.3 2.2 21.9 11.6 8.0 16.4 0.8 6.6 6.5 3.2 3.9 24.4 16.6 7.9 81.1 17.6 3.9 10.2 115.1 4.7 6.2 47.3 28.2 3.7 12.7 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 1.4 0.0 147.0 0.0 0.0 0.0 152.5 375.9 0.0 0.0 0.0 0.0 0.0 0.1 49.7 1.1 80.4 0.0 0.0 91.4 53.2 0.5 0.0 0.0 14.0 0.0 45.5 0.0 0.0 0.1 0.1 0.1 0.0 0.4 0.3 0.0 80.8 0.1 0.0 0.1 0.2 0.1 1.4 14.6 0.2 0.3 99.9 1.7 56.8 20.4 76.6 40.5 42.5 40.2 2.7 32.4 38.6 26.6 1.0 29.8 31.0 68.9 41.7 65.8 5.3 39.8 22.9 5.0 5.7 5.9 22.9 5.1 6.9 12.2 8.4 11.6 7.9 10.2 12.7 13.4 16.0 29.2 0.7 12.2 3.2 0.2 0.1 0.0 0.2 0.9 2.8 4.8 1.5 5.6 1.8 0.0 0.5 35.2 0.1 0.0 0.2 1.6 0.4 2.4 14.2 0.0 24.0 2.8 0.0 0.8 9.5 5.1 0.7 129.6 0.0 18.9 2.4 57.9 0.0 7.9 0.7 0.0 154.4 49.4 0.9 2.5 158.2 1.8 31.9 48.2 0.0 91.6 0.5 0.5 0.0 0.0 3.0 12.6 0.4 0.0 0.3 2.9 0.0 26.3 1.3 3.1 0.0 0.2 1.0 1.8 0.8 104.6 0.5 0.0 0.3 LDB2 "CLIM1, LDB1" ENSG00000169744 "LIM domain binding 2" O43679 4 16501541-16898678 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 236.5;Endothelial cells: 194.4;Excitatory neurons: 1314.4;Hepatic stellate cells: 364.8;Inhibitory neurons: 196.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "NK-cell: 2.0" "Lineage enriched" "Detected in single" 13 "NK-cells: 2.0" "Cell line enhanced" "Detected in many" "AF22: 18.3;fHDF/TERT166: 19.0;HAP1: 34.4;HUVEC TERT2: 65.3;TIME: 17.1;U-138 MG: 25.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017544, HPA068634" Supported Supported "Nucleoplasm,Nucleoli,Plasma membrane" No NA "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nucleoli" "Plasma membrane" "CAB017544: AB_2137013, HPA068634: AB_2686012" "unprognostic (3.43e-1)" "unprognostic (2.77e-1)" "unprognostic (9.10e-2)" "unprognostic (4.37e-1)" "unprognostic (7.25e-2)" "unprognostic (4.62e-3)" "unprognostic (2.10e-3)" "unprognostic (1.57e-1)" "unprognostic (2.94e-2)" "unprognostic (2.82e-1)" "unprognostic (2.67e-2)" "unprognostic (1.96e-2)" "unprognostic (2.05e-3)" "unprognostic (1.26e-3)" "unprognostic (1.60e-1)" "unprognostic (9.63e-2)" "unprognostic (7.10e-3)" 58.9 15.5 13.7 8.0 19.8 0.4 52.2 3.3 45.9 43.5 7.6 12.7 6.5 65.5 23.4 15.8 28.0 31.2 33.7 23.3 7.3 28.0 26.0 58.2 11.5 4.4 10.9 18.2 7.6 17.0 9.0 58.8 4.7 18.0 8.5 5.3 10.8 13.7 14.0 9.4 12.8 53.8 7.1 50.4 11.5 5.0 7.9 8.3 31.3 24.3 4.8 22.5 22.8 19.7 0.0 0.0 18.3 0.1 10.5 16.9 0.0 10.2 8.0 1.2 2.7 0.0 0.0 0.0 0.0 19.0 0.0 0.0 34.4 0.0 7.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 9.5 0.0 12.5 0.0 2.7 65.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.7 0.0 0.1 8.8 0.0 0.0 0.8 0.0 0.0 2.3 0.0 0.0 0.0 4.9 0.0 0.0 17.1 25.7 0.1 1.2 0.0 8.3 0.1 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.2 13.7 19.8 3.3 45.9 23.3 7.3 4.4 10.9 4.7 7.1 7.9 19.7 236.5 0.0 5.5 44.7 1.5 8.7 0.3 0.0 2.8 27.1 1.7 2.2 8.7 2.8 0.0 0.0 0.0 0.2 6.8 0.0 0.0 4.4 1.3 1.4 36.5 194.4 0.0 8.0 1314.4 0.2 0.2 44.4 4.1 1.1 5.7 0.1 364.8 3.1 0.4 0.0 196.5 0.0 0.0 16.4 13.2 2.6 38.2 1.4 8.8 117.1 0.0 10.4 3.1 120.6 36.7 0.2 0.0 50.4 0.0 0.3 0.0 0.1 0.7 2.1 6.6 2.8 19.3 0.2 0.7 1.3 6.8 0.1 4.9 39.7 0.0 0.5 LDLRAD2 ENSG00000187942 "Low density lipoprotein receptor class A domain containing 2" Q5SZI1 1 21812265-21825225 "Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 2.2;Granulosa cells: 4.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 1.2;THP-1: 1.0;TIME: 2.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "basal ganglia: 4.0;midbrain: 5.9" HPA030478 Approved "Secreted - unknown location" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "HPA030478: AB_10601541" "unprognostic (4.16e-2)" "unprognostic (1.22e-1)" "unprognostic (4.13e-2)" "unprognostic (4.21e-2)" "unprognostic (1.78e-1)" "unprognostic (6.22e-3)" "unprognostic (1.35e-2)" "unprognostic (4.85e-2)" "unprognostic (7.52e-2)" "unprognostic (3.80e-2)" "unprognostic (5.34e-2)" "unprognostic (5.38e-2)" "unprognostic (1.04e-3)" "unprognostic (7.39e-3)" "unprognostic (3.14e-1)" "unprognostic (1.26e-1)" "unprognostic (6.94e-2)" 3.7 2.8 0.4 0.8 0.3 1.0 3.0 0.2 0.1 2.7 0.4 4.3 1.6 3.5 0.0 1.7 2.7 0.5 6.8 0.7 1.1 2.2 0.7 1.6 0.7 2.4 3.3 1.1 2.0 0.0 1.5 0.1 1.7 3.7 0.1 0.0 7.2 0.0 1.2 1.3 2.4 0.1 1.7 2.7 3.7 1.4 1.4 0.0 2.2 0.0 0.3 3.9 2.4 0.3 0.2 0.2 0.1 0.2 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.5 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.9 0.1 0.1 1.2 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.0 1.0 2.2 0.2 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.4 0.3 0.2 0.1 0.7 1.1 2.4 3.3 1.7 1.7 1.4 0.3 2.2 0.0 0.6 0.0 0.6 0.5 0.1 0.4 0.6 0.0 0.1 0.1 0.7 0.0 0.2 1.8 0.0 0.2 0.3 0.0 0.0 0.2 1.7 0.3 1.2 1.6 0.0 1.3 0.2 0.0 0.6 1.3 0.0 0.9 0.0 4.9 0.7 0.2 0.3 0.0 0.1 0.0 0.0 0.3 0.2 0.4 0.0 0.3 0.0 1.0 0.5 0.0 0.0 0.0 0.2 0.3 0.1 0.0 1.3 0.5 0.0 0.0 0.8 0.0 0.0 1.2 0.7 0.6 1.2 0.1 0.4 0.3 0.4 0.4 0.0 0.0 LDOC1 "BCUR1, Mar7, Mart7, RTL7, SIRH7" ENSG00000182195 "LDOC1 regulator of NFKB signaling" O95751 X 141111605-141177129 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 123.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 43.0;Proximal tubular cells: 43.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 6.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 24.7;MCF7: 31.9;PC-3: 34.3;U-251 MG: 21.9" "Region enriched" "Detected in many" 5 "cerebellum: 19.2" "HPA051768, HPA061842" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Nucleoli" "HPA051768: AB_2681599, HPA061842: AB_2684624" "unprognostic (4.09e-1)" "unprognostic (4.72e-2)" "unprognostic (1.88e-1)" "unprognostic (1.73e-3)" "unprognostic (2.47e-1)" "unprognostic (2.42e-1)" "unprognostic (4.51e-2)" "unprognostic (2.08e-2)" "unprognostic (8.92e-2)" "unprognostic (1.21e-1)" "unprognostic (6.40e-3)" "unprognostic (1.21e-1)" "unprognostic (1.27e-2)" "unprognostic (1.98e-2)" "unprognostic (3.06e-2)" "unprognostic (4.38e-3)" "unprognostic (2.76e-2)" 32.3 34.0 4.7 0.9 5.5 0.1 28.0 2.9 8.5 45.8 0.2 18.8 0.9 53.9 1.8 21.4 48.5 1.6 15.1 6.2 5.8 33.2 4.8 19.6 0.8 5.3 5.0 46.8 19.3 10.5 123.3 0.0 5.0 34.3 0.3 3.4 55.1 5.9 5.5 31.5 12.5 2.0 1.2 14.2 18.4 10.8 5.0 0.9 53.7 0.4 0.7 33.1 30.6 6.0 0.0 24.7 3.0 8.4 5.0 6.2 0.0 5.0 5.8 6.3 8.8 0.0 8.0 0.0 4.2 7.7 6.1 10.4 3.4 7.1 4.5 0.0 6.6 0.0 11.7 0.0 2.0 0.0 1.9 10.9 3.6 5.5 2.9 5.1 5.7 0.0 0.1 0.0 5.7 31.9 0.0 0.0 3.3 0.0 34.3 0.0 2.7 0.0 7.7 4.7 0.0 3.2 0.0 4.0 0.0 1.6 5.1 0.0 11.9 0.0 6.8 0.0 21.9 0.0 0.0 0.0 3.5 0.0 0.0 3.1 0.0 0.0 1.2 0.0 0.8 0.9 2.5 0.8 0.2 2.1 2.2 1.4 0.0 6.4 0.0 1.4 2.6 1.0 4.7 5.5 2.9 8.5 6.2 5.8 5.3 5.0 5.0 1.2 5.0 6.0 8.6 0.0 5.3 4.2 4.9 6.0 16.8 4.6 16.5 29.3 23.8 20.2 2.2 30.0 8.2 23.9 8.4 2.8 5.7 0.1 43.0 13.8 0.7 7.8 13.5 12.8 5.4 0.8 9.4 14.0 1.8 16.1 3.6 6.0 2.5 8.8 12.8 0.1 0.9 20.2 9.9 0.4 8.2 0.3 1.8 1.1 22.1 1.0 3.6 7.5 0.3 21.2 5.2 7.1 15.0 13.7 0.2 38.7 0.9 11.9 0.0 43.8 4.6 13.0 13.1 15.3 26.2 0.9 7.6 16.7 6.8 1.5 5.2 13.5 0.3 15.0 LEF1 "TCF10, TCF1ALPHA, TCF7L3" ENSG00000138795 "Lymphoid enhancer binding factor 1" Q9UJU2 4 108047545-108168956 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "lymphoid tissue: 349.2" "Cell type enhanced" "Detected in many" "Melanocytes: 33.8;Microglial cells: 145.2;T-cells: 70.3" "Cancer enhanced" "Detected in all" "melanoma: 25.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 142.6" "Lineage enriched" "Detected in many" 4 "T-cells: 142.6" "Group enriched" "Detected in many" 5 "JURKAT: 579.6;MOLT-4: 569.0;REH: 454.8" "Region enhanced" "Detected in all" "thalamus: 22.6" "Low region specificity" "Detected in all" "HPA002087, CAB019405" Enhanced Approved Nucleoplasm NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm "CAB019405: AB_823558, HPA002087: AB_1079245" "unprognostic (1.03e-3)" "unprognostic (7.36e-3)" "unprognostic (2.97e-2)" "prognostic favorable (1.37e-5)" "unprognostic (9.08e-2)" "unprognostic (5.24e-2)" "unprognostic (3.81e-2)" "unprognostic (1.10e-2)" "unprognostic (1.77e-1)" "unprognostic (5.21e-2)" "unprognostic (9.99e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.47e-6)" "unprognostic (1.12e-1)" "unprognostic (5.22e-2)" "unprognostic (7.88e-2)" "unprognostic (8.91e-2)" 1.0 12.7 10.7 13.8 7.6 11.6 2.0 6.1 7.9 4.2 14.3 1.5 0.7 8.0 4.8 3.2 5.1 3.9 0.2 5.7 9.9 2.5 0.3 3.3 31.3 8.9 11.2 1.1 0.1 0.3 1.0 11.0 9.4 3.7 1.4 0.5 1.0 1.0 0.1 2.8 4.1 3.9 5.9 9.8 1.5 12.3 18.2 349.2 3.0 0.1 22.8 5.5 3.0 5.5 0.1 0.0 8.0 0.0 0.0 0.0 0.0 0.2 7.2 1.8 4.7 27.1 0.0 0.0 0.1 0.0 2.5 0.2 7.9 0.0 3.7 0.3 17.6 6.9 0.0 0.0 0.0 23.6 2.9 0.4 0.4 0.0 0.7 3.5 0.0 579.6 14.2 0.0 2.6 1.0 569.0 0.0 1.7 6.3 1.4 454.8 9.1 0.2 2.4 1.3 3.0 5.2 0.0 0.5 83.8 6.7 2.4 0.2 0.0 11.9 10.3 0.0 15.3 38.3 17.0 100.9 7.8 0.0 48.4 0.3 0.2 0.0 8.2 0.0 1.6 0.6 68.3 29.9 0.1 0.9 142.6 102.2 1.9 32.9 0.3 0.5 97.7 36.8 10.7 7.6 6.1 7.9 5.7 9.9 8.9 11.2 9.4 5.9 18.2 5.5 1.4 3.2 1.9 2.0 4.4 3.3 1.4 1.0 24.5 0.1 0.4 5.0 1.6 0.0 0.7 0.0 0.0 0.1 6.2 0.0 13.7 0.0 4.2 5.8 22.3 22.0 0.0 9.2 0.2 0.0 0.2 2.1 0.0 4.5 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.2 4.1 0.3 1.4 7.9 0.6 2.0 33.8 145.2 3.5 0.6 10.3 0.5 0.6 0.1 0.0 0.0 5.4 1.8 0.0 0.5 2.3 0.3 0.0 0.6 9.0 16.1 6.6 11.3 1.3 0.4 70.3 0.0 0.9 0.4 LGSN "GLULD1, LGS" ENSG00000146166 "Lengsin, lens protein with glutamine synthetase domain" Q5TDP6 6 63275951-63319983 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 2.0;liver: 3.8;placenta: 1.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 3.5;Inhibitory neurons: 3.7;Late spermatids: 4.4;Oligodendrocytes: 5.9;Proximal tubular cells: 5.6;Respiratory ciliated cells: 3.0" "Cancer enriched" "Detected in some" 4 "lung cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 6.2;BEWO: 3.3;CACO-2: 1.6;HeLa: 1.8;Karpas-707: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA030957, HPA039983" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Vesicles" "HPA030957: AB_10670149, HPA039983: AB_2676784" "unprognostic (1.94e-1)" "unprognostic (1.72e-1)" "unprognostic (1.12e-1)" "unprognostic (9.03e-2)" "unprognostic (2.81e-1)" "unprognostic (1.01e-1)" "unprognostic (5.05e-4)" "unprognostic (1.26e-1)" "unprognostic (1.74e-1)" "unprognostic (1.08e-1)" "unprognostic (2.13e-1)" "unprognostic (2.53e-2)" "unprognostic (4.51e-3)" "unprognostic (1.64e-3)" "unprognostic (1.31e-1)" "unprognostic (2.19e-1)" 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.4 0.2 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 2.0 3.8 0.2 0.0 0.3 0.1 0.0 0.3 0.0 0.0 1.1 0.2 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 6.2 0.0 0.0 0.0 0.0 3.3 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.4 0.2 0.1 0.1 0.3 0.1 0.2 0.1 0.1 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.0 0.0 0.0 2.2 0.0 1.1 1.9 0.1 1.2 2.0 0.0 0.1 0.0 0.0 3.5 0.2 0.5 0.1 0.0 0.0 0.0 0.3 0.0 1.1 0.3 0.0 3.7 0.7 0.0 0.3 0.0 4.4 0.3 0.1 0.0 1.9 0.0 0.0 0.0 1.5 5.9 0.0 0.3 0.0 0.1 0.2 0.1 5.6 3.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 1.4 0.1 0.1 0.8 0.2 LILRA1 "CD85i, LIR-6, LIR6" ENSG00000104974 "Leukocyte immunoglobulin like receptor A1" O75019 19 54593582-54602381 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 11.9" "Group enriched" "Detected in some" 8 "Kupffer cells: 42.3;Macrophages: 38.7;monocytes: 39.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 126.8;non-classical monocyte: 169.2" "Lineage enriched" "Detected in many" 5 "monocytes: 169.2" "Group enriched" "Detected in some" 8 "THP-1: 1.0;U-937: 1.5" NA NA 94000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (4.52e-2)" "unprognostic (1.12e-1)" "unprognostic (6.30e-2)" "unprognostic (1.59e-1)" "unprognostic (2.34e-1)" "unprognostic (9.46e-3)" "unprognostic (1.17e-1)" "unprognostic (4.07e-2)" "unprognostic (1.12e-1)" "unprognostic (4.90e-2)" "unprognostic (8.72e-2)" "unprognostic (1.13e-1)" "unprognostic (8.28e-3)" "unprognostic (8.82e-2)" "unprognostic (3.79e-4)" "unprognostic (2.53e-1)" "unprognostic (9.83e-2)" 0.7 0.5 0.3 8.2 0.3 2.6 0.2 0.4 0.3 0.1 0.2 0.3 0.1 0.1 0.1 0.2 0.3 0.8 0.3 0.2 0.4 0.3 0.9 1.8 1.1 0.9 0.6 0.1 0.2 0.1 0.2 0.4 0.7 0.3 0.6 0.0 0.2 0.2 0.1 0.0 0.5 0.7 0.8 11.9 0.2 0.0 0.7 0.3 0.2 0.6 1.1 2.1 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.2 47.0 36.0 0.0 126.8 0.0 0.0 0.0 0.1 32.6 0.1 0.1 0.1 35.8 0.4 169.2 4.2 0.1 22.7 0.3 0.3 0.4 0.3 0.2 0.4 0.9 0.6 0.7 0.8 0.7 1.1 0.1 0.0 1.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.8 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.4 4.9 0.0 0.0 0.0 0.0 42.3 0.7 0.0 0.0 38.7 0.0 2.8 39.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 LILRA2 "CD85h, ILT1, LIR-7, LIR7" ENSG00000239998 "Leukocyte immunoglobulin like receptor A2" Q8N149 19 54572920-54590287 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.5;lymphoid tissue: 57.4" "Group enriched" "Detected in some" 5 "Hofbauer cells: 22.0;Kupffer cells: 79.9;Macrophages: 39.1;monocytes: 48.7" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 31.6" "Group enriched" "Detected in many" 6 "granulocytes: 31.6;monocytes: 11.6" "Cell line enhanced" "Detected in some" "NB-4: 1.7;REH: 2.0;THP-1: 4.0;U-937: 9.1" "Secreted to blood" NA NA 140000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (2.04e-1)" "unprognostic (7.72e-2)" "unprognostic (6.94e-2)" "unprognostic (1.78e-1)" "unprognostic (1.54e-2)" "unprognostic (2.65e-2)" "unprognostic (8.45e-2)" "unprognostic (3.56e-2)" "unprognostic (1.22e-1)" "unprognostic (3.53e-5)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (5.43e-2)" "unprognostic (5.58e-2)" "unprognostic (3.30e-4)" "unprognostic (4.21e-2)" "unprognostic (6.59e-2)" 5.2 3.2 0.9 2.8 1.0 15.5 1.8 1.0 1.5 0.9 0.9 1.5 0.2 1.0 0.2 0.9 4.0 0.4 1.9 1.0 1.0 1.4 3.4 10.3 0.2 2.0 1.2 0.8 1.4 0.1 0.8 0.1 2.0 1.4 0.2 0.2 1.7 0.1 0.5 0.7 1.7 0.4 1.1 57.4 1.6 0.8 1.6 0.2 0.8 0.2 0.3 2.2 1.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 2.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.1 0.0 5.3 7.6 3.0 0.1 11.6 0.1 0.1 0.1 0.1 3.3 0.3 0.1 0.1 31.6 0.4 11.3 0.7 0.1 6.1 0.9 1.0 1.0 1.5 1.0 1.0 2.0 1.2 2.0 1.1 1.6 1.8 0.2 3.2 3.0 0.0 0.3 0.3 1.6 0.0 0.0 0.9 0.4 0.1 0.5 1.5 1.8 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.8 0.0 0.2 0.2 0.6 0.0 0.1 6.3 0.1 0.4 0.4 22.0 0.0 0.0 0.0 0.0 79.9 5.9 0.6 0.0 39.1 0.0 8.4 48.7 0.0 2.1 0.0 0.1 0.0 0.0 0.0 1.1 1.0 0.0 0.1 1.5 0.6 0.0 2.1 0.3 0.3 0.3 0.0 0.1 0.4 1.4 0.0 0.0 0.6 LILRB1 "CD85, CD85j, ILT2, LIR-1, LIR1, MIR-7, PIR-B, PIRB" ENSG00000104972 "Leukocyte immunoglobulin like receptor B1" 19 54617158-54637528 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 36.1" "Cell type enhanced" "Detected in some" "B-cells: 32.3;dendritic cells: 37.4;Kupffer cells: 87.3;Macrophages: 73.8;Microglial cells: 30.9;monocytes: 39.6;Plasma cells: 34.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 6 "intermediate monocyte: 39.3;non-classical monocyte: 63.7" "Lineage enriched" "Detected in many" 11 "monocytes: 63.7" "Group enriched" "Detected in some" 19 "Daudi: 5.6;THP-1: 2.9" "Intracellular and membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (9.23e-2)" "unprognostic (4.20e-2)" "unprognostic (4.95e-2)" "unprognostic (3.29e-2)" "unprognostic (1.11e-1)" "unprognostic (1.43e-2)" "unprognostic (1.24e-1)" "unprognostic (3.89e-2)" "unprognostic (3.58e-1)" "unprognostic (9.64e-2)" "unprognostic (1.24e-1)" "unprognostic (5.92e-2)" "prognostic unfavorable (3.08e-6)" "unprognostic (6.57e-2)" "unprognostic (1.62e-2)" "unprognostic (7.06e-2)" "unprognostic (8.03e-2)" 2.5 1.6 0.2 7.0 0.2 1.2 1.0 0.2 0.3 0.6 0.2 2.1 0.1 0.4 0.0 0.7 1.5 0.0 0.9 0.2 0.3 1.2 2.2 7.6 5.6 0.6 0.5 0.6 0.7 0.0 0.9 0.1 0.8 1.1 0.4 0.0 1.2 0.2 0.2 0.1 6.0 2.7 0.7 36.1 1.1 0.2 0.7 0.0 0.8 0.0 0.3 2.1 0.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 8.1 0.0 1.4 39.3 0.0 2.3 0.0 1.2 5.6 2.4 0.0 0.8 0.2 0.0 63.7 2.2 0.0 5.5 0.2 0.2 0.2 0.3 0.2 0.3 0.6 0.5 0.8 0.7 0.7 1.4 0.9 0.0 2.2 0.0 32.3 0.3 0.3 0.0 0.0 0.0 0.3 0.8 1.0 1.5 2.5 0.0 0.0 0.0 37.4 0.0 0.0 0.0 0.3 0.0 0.0 2.0 0.0 1.3 0.0 0.0 0.1 0.2 0.5 0.0 2.5 0.0 2.5 0.7 15.9 0.0 0.1 0.0 0.0 87.3 2.2 0.0 0.0 73.8 0.0 30.9 39.6 0.3 9.2 0.0 0.1 0.0 0.0 0.0 34.0 0.3 0.0 0.3 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.3 9.5 0.0 0.1 2.2 LILRB3 "CD85a, HL9, ILT5, LIR-3, LIR3, PIR-B, PIRB" ENSG00000204577 "Leukocyte immunoglobulin like receptor B3" O75022 19 54216278-54223506 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 27.0;lymphoid tissue: 49.9" "Group enriched" "Detected in many" 5 "Hofbauer cells: 63.4;Kupffer cells: 88.6;Macrophages: 88.8;monocytes: 71.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 44.8" "Group enriched" "Detected in many" 4 "granulocytes: 44.8;monocytes: 15.4" "Not detected" "Not detected" HPA026985 Approved "Plasma membrane,Cytosol" NA NA 16000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "HPA026985: " "unprognostic (7.51e-2)" "unprognostic (3.52e-2)" "unprognostic (9.59e-2)" "unprognostic (4.53e-1)" "unprognostic (1.83e-3)" "unprognostic (5.28e-3)" "unprognostic (2.91e-2)" "unprognostic (2.55e-1)" "unprognostic (5.58e-2)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.63e-1)" "unprognostic (1.92e-8)" "unprognostic (2.18e-1)" "unprognostic (2.19e-3)" "unprognostic (1.84e-1)" "unprognostic (1.75e-1)" 9.9 3.4 0.4 8.3 0.4 14.6 2.9 0.4 2.1 1.2 0.9 2.7 0.3 1.2 0.3 1.3 5.4 0.1 3.4 0.4 0.4 2.3 4.1 27.0 0.3 1.2 0.8 1.0 1.9 0.0 1.3 1.2 1.3 1.7 0.0 0.2 2.4 0.0 1.1 0.8 2.6 0.1 0.6 49.9 2.3 0.5 1.8 0.6 1.6 0.0 0.2 3.2 1.6 1.4 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 15.4 0.6 0.1 14.3 0.2 0.1 0.3 0.0 7.2 0.1 0.0 0.1 44.8 0.0 5.6 0.5 0.0 11.6 0.4 0.4 0.4 2.1 0.4 0.4 1.2 0.8 1.3 0.6 1.8 1.4 1.5 9.6 13.0 0.3 2.2 2.4 1.2 6.5 0.0 0.7 1.6 2.2 0.4 4.3 8.3 1.8 0.0 1.5 2.1 0.6 0.0 0.3 1.3 0.8 1.9 3.0 0.0 0.8 0.2 0.6 6.7 2.9 0.0 2.2 7.6 0.5 1.8 3.2 63.4 0.0 0.1 1.9 0.0 88.6 8.4 4.1 0.3 88.8 1.8 1.9 71.2 0.9 3.1 0.0 0.1 0.2 1.3 0.7 2.1 1.6 0.4 0.4 5.2 2.9 6.6 4.3 1.3 0.8 1.5 0.1 3.0 1.2 3.8 2.6 2.0 0.4 LILRB4 "CD85k, HM18, ILT3, LIR-5, LIR5" ENSG00000186818 "Leukocyte immunoglobulin like receptor B4" Q8NHJ6 19 54643889-54670359 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 13.7;lymphoid tissue: 18.8" "Cell type enhanced" "Detected in some" "dendritic cells: 76.9;Hofbauer cells: 127.6;Kupffer cells: 118.9;Macrophages: 104.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 37.3" "Group enriched" "Detected in many" 44 "dendritic cells: 37.3;monocytes: 10.8" "Cell line enriched" "Detected in some" 32 "Karpas-707: 407.8" HPA052807 Approved NA NA 11000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA052807: AB_2681958" "unprognostic (4.09e-2)" "unprognostic (5.75e-3)" "unprognostic (6.06e-2)" "unprognostic (1.91e-2)" "unprognostic (1.82e-1)" "unprognostic (1.55e-1)" "unprognostic (5.03e-2)" "unprognostic (3.53e-1)" "unprognostic (4.13e-2)" "unprognostic (1.52e-1)" "unprognostic (5.43e-1)" "unprognostic (2.79e-1)" "unprognostic (1.91e-2)" "unprognostic (1.08e-1)" "unprognostic (4.42e-2)" "unprognostic (4.51e-2)" "unprognostic (4.52e-2)" 8.6 4.6 2.2 10.9 2.5 2.0 3.6 2.7 4.2 1.1 2.2 4.1 1.6 0.9 0.3 1.0 4.0 1.7 2.3 2.2 2.8 2.2 2.9 13.7 11.4 3.8 3.2 0.7 1.6 0.1 2.2 1.4 3.5 1.9 2.3 0.1 3.6 0.3 0.5 0.5 6.3 0.7 3.2 18.8 1.7 0.3 3.0 0.6 2.4 0.0 2.1 6.1 0.8 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 407.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 1.4 12.8 0.0 0.2 0.0 0.4 0.0 7.8 0.0 0.0 10.8 0.0 0.2 0.0 0.0 11.7 0.5 0.0 0.0 0.1 0.1 8.9 37.3 0.0 3.8 2.2 2.5 2.7 4.2 2.2 2.8 3.8 3.2 3.5 3.2 3.0 3.3 0.6 0.0 4.1 0.0 13.4 0.4 0.0 0.0 0.0 0.2 0.3 1.7 1.0 1.5 1.3 0.0 0.0 0.3 76.9 0.1 0.0 0.0 0.2 0.0 0.0 4.2 0.0 7.8 0.1 0.0 0.9 0.5 0.0 0.0 1.3 0.0 2.2 0.8 127.6 0.0 0.2 0.0 0.0 118.9 12.6 0.6 0.0 104.0 1.8 14.0 29.3 0.2 1.0 0.0 0.0 0.1 0.0 0.0 24.3 0.0 0.0 0.0 0.0 0.2 6.6 0.2 0.1 0.0 0.4 0.1 0.1 0.8 2.2 0.0 0.2 0.1 LILRB5 "CD85c, LIR-8, LIR8" ENSG00000105609 "Leukocyte immunoglobulin like receptor B5" O75023 19 54249421-54257301 "CD markers, Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 17.9;lymphoid tissue: 49.1" "Group enriched" "Detected in some" 6 "Hofbauer cells: 61.1;Kupffer cells: 103.4;Macrophages: 40.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA012069 Approved NA NA 58000000 "Cluster 17: Basophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA012069: AB_1852873" "unprognostic (3.55e-3)" "unprognostic (5.38e-2)" "unprognostic (2.20e-2)" "unprognostic (7.03e-2)" "unprognostic (8.86e-2)" "unprognostic (5.44e-2)" "unprognostic (3.02e-5)" "unprognostic (6.80e-2)" "unprognostic (2.23e-1)" "unprognostic (2.33e-1)" "unprognostic (9.95e-2)" "unprognostic (8.68e-2)" "unprognostic (3.31e-1)" "unprognostic (2.07e-1)" "unprognostic (4.14e-2)" "unprognostic (1.42e-2)" "unprognostic (1.73e-1)" 17.9 10.3 0.2 1.7 0.5 0.9 7.2 0.3 1.0 1.6 1.3 6.1 4.6 1.1 0.8 1.8 4.4 2.8 5.1 0.2 0.2 1.6 7.1 5.3 1.8 0.5 0.3 1.3 0.8 0.3 0.7 4.8 0.4 0.6 4.8 0.1 2.9 0.6 1.8 2.3 6.8 2.4 0.2 49.1 2.5 1.1 1.0 1.0 1.4 1.3 0.7 4.2 1.2 1.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.2 0.5 0.3 1.0 0.2 0.2 0.5 0.3 0.4 0.2 1.0 1.1 0.5 0.0 1.1 0.0 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.5 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 1.7 0.0 0.1 0.2 0.0 2.7 0.0 0.0 0.4 0.7 0.0 0.1 0.0 0.1 8.6 0.9 61.1 0.0 0.0 0.0 0.0 103.4 9.8 1.8 0.0 40.1 1.8 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.5 0.0 0.1 0.3 1.1 0.8 0.4 0.5 0.0 0.0 LIMD2 MGC10986 ENSG00000136490 "LIM domain containing 2" Q9BT23 17 63695888-63701172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 112.1;lymphoid tissue: 222.2" "Cell type enhanced" "Detected in many" "B-cells: 436.9;dendritic cells: 306.6;Kupffer cells: 216.1;monocytes: 188.2;NK-cells: 510.9;T-cells: 264.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 243.0;NB-4: 171.7;SH-SY5Y: 163.3;THP-1: 127.6;U-698: 260.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062432, HPA075172" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm Cytosol "HPA062432: , HPA075172: " "unprognostic (2.90e-3)" "unprognostic (2.89e-3)" "unprognostic (6.34e-2)" "unprognostic (6.53e-2)" "unprognostic (8.72e-2)" "unprognostic (2.00e-3)" "unprognostic (1.81e-1)" "unprognostic (2.67e-2)" "unprognostic (6.68e-2)" "unprognostic (2.01e-2)" "unprognostic (1.20e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (5.36e-11)" "unprognostic (1.21e-1)" "unprognostic (2.21e-1)" "unprognostic (2.26e-2)" "unprognostic (6.08e-2)" 12.5 7.9 26.2 106.9 31.3 112.1 8.2 18.8 35.4 12.1 19.1 11.2 13.6 7.8 2.0 6.4 8.9 17.5 9.8 29.9 22.6 17.3 10.4 24.8 222.2 22.9 22.1 7.1 7.1 3.3 10.7 15.5 22.3 16.3 9.4 1.0 12.9 5.5 3.1 6.7 61.0 9.1 21.8 170.8 20.5 14.0 22.8 111.3 9.3 3.4 149.8 20.3 8.2 23.7 0.8 7.7 92.9 22.9 0.8 2.4 2.3 2.6 1.4 9.4 6.4 4.2 1.9 243.0 20.5 11.6 9.4 3.9 20.4 0.9 2.6 84.3 8.7 72.4 1.8 20.6 17.6 95.2 7.6 22.8 1.0 9.6 0.3 11.0 25.5 16.5 6.7 13.8 10.7 1.3 84.7 171.7 50.3 0.0 4.4 34.6 37.4 43.6 13.1 1.0 111.2 163.3 11.8 0.2 22.2 23.9 0.6 127.6 32.2 12.8 28.1 0.7 3.4 2.9 1.0 260.4 1.4 13.3 22.7 2144.2 601.8 1434.7 368.9 716.3 364.8 688.5 512.2 432.9 609.8 855.0 679.3 496.3 1248.9 553.2 783.9 230.5 664.2 991.4 26.2 31.3 18.8 35.4 29.9 22.6 22.9 22.1 22.3 21.8 22.8 23.7 11.0 0.0 4.6 0.7 436.9 7.5 7.7 20.5 2.2 1.9 5.0 7.2 1.0 4.3 8.6 11.0 4.2 1.6 306.6 1.1 5.9 20.5 18.8 2.3 14.2 23.6 22.2 99.2 18.7 8.9 3.6 10.1 5.6 4.2 53.3 15.7 30.4 2.0 137.6 3.3 2.2 2.1 26.4 216.1 93.9 57.5 3.4 148.0 37.4 12.2 188.2 8.4 510.9 3.5 2.9 19.8 4.7 4.9 154.3 17.7 0.4 3.7 2.4 1.1 6.6 2.9 30.5 7.8 7.5 1.1 6.0 1.5 264.3 4.7 2.5 4.3 LMBRD1 "bA810I22.1, C6orf209, cblF, FLJ11240" ENSG00000168216 "LMBR1 domain containing 1" Q9NUN5 6 69672757-69867236 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Endocytosis, Gastrulation, Host-virus interaction, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 21.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016491, HPA019547" Uncertain Supported Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 25: RPMI-8226 - Immune response" "Cluster 59: Non-specific - Transcription" Vesicles "HPA016491: , HPA019547: AB_2281256" "unprognostic (1.44e-1)" "unprognostic (3.84e-2)" "unprognostic (7.67e-2)" "unprognostic (7.64e-2)" "unprognostic (2.41e-1)" "unprognostic (5.37e-2)" "unprognostic (2.26e-1)" "unprognostic (4.39e-2)" "unprognostic (2.19e-1)" "unprognostic (1.97e-1)" "unprognostic (2.22e-1)" "unprognostic (1.47e-1)" "prognostic favorable (1.07e-7)" "unprognostic (7.99e-2)" "unprognostic (1.67e-1)" "unprognostic (2.60e-2)" "unprognostic (2.68e-2)" 33.3 49.4 10.3 11.5 10.8 4.2 31.4 20.7 17.0 28.9 13.3 26.4 13.5 22.5 27.7 25.7 26.3 16.0 27.7 11.1 11.5 53.0 42.9 27.9 12.1 13.6 11.9 34.5 36.5 31.7 26.5 17.2 12.3 19.1 20.5 10.7 33.2 20.0 28.8 28.1 28.6 12.7 11.4 21.8 29.6 10.4 10.2 9.1 35.1 13.1 16.8 30.1 29.4 16.1 3.8 3.8 6.0 10.2 16.5 23.7 17.9 2.2 7.1 2.6 5.6 4.8 8.2 6.5 9.2 8.8 5.8 7.5 3.8 9.8 2.4 16.3 11.9 6.2 4.9 7.8 13.7 3.4 8.7 7.6 9.6 0.8 5.7 19.1 7.4 5.5 9.4 6.1 6.0 8.1 2.5 4.7 4.6 8.5 4.8 0.3 15.4 37.8 17.0 13.8 5.5 8.5 0.9 7.0 13.3 3.0 4.6 25.3 1.1 3.9 4.6 4.3 2.8 8.8 5.5 2.8 2.3 4.0 12.3 6.5 2.2 3.9 2.0 2.5 2.5 12.1 2.9 1.9 1.7 21.0 3.1 2.3 11.4 2.6 4.8 2.2 3.7 2.1 10.3 10.8 20.7 17.0 11.1 11.5 13.6 11.9 12.3 11.4 10.2 16.1 49.7 64.1 38.3 82.3 93.4 29.1 41.9 45.2 71.2 73.7 39.2 25.4 40.6 50.1 56.0 58.8 110.5 69.6 36.2 79.0 19.6 49.0 28.8 48.3 22.7 41.1 18.7 18.5 119.2 49.6 59.2 56.1 36.7 61.7 40.5 15.7 44.6 60.5 42.1 55.5 144.6 37.6 44.7 66.9 36.3 9.3 35.4 52.0 32.0 79.6 49.3 56.3 28.8 122.2 156.6 42.0 51.0 33.8 82.7 19.6 78.7 64.1 65.5 90.8 26.3 36.4 33.9 22.5 16.9 43.4 38.1 77.4 43.2 26.9 31.7 34.2 LMBRD2 DKFZp434H2226 ENSG00000164187 "LMBR1 domain containing 2" Q68DH5 5 36098407-36151887 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 71.4;Inhibitory neurons: 51.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 10.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 10.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012165 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "HPA012165: AB_2136131" "unprognostic (9.43e-3)" "unprognostic (3.03e-1)" "unprognostic (1.80e-2)" "unprognostic (7.09e-2)" "unprognostic (1.79e-1)" "unprognostic (9.53e-3)" "unprognostic (6.58e-2)" "unprognostic (8.46e-3)" "unprognostic (6.45e-3)" "unprognostic (2.80e-1)" "unprognostic (8.61e-2)" "unprognostic (6.94e-2)" "unprognostic (2.30e-3)" "unprognostic (7.53e-2)" "unprognostic (1.11e-1)" "unprognostic (1.65e-2)" "unprognostic (5.35e-2)" 4.6 6.6 4.8 5.0 7.2 1.7 6.1 3.6 9.5 4.7 2.2 6.3 7.0 3.4 4.9 4.7 3.2 4.1 6.0 9.0 4.1 7.2 10.3 4.1 5.9 2.1 3.8 3.2 5.0 10.7 4.7 6.1 2.6 6.6 6.3 6.9 6.0 4.4 5.5 5.5 7.1 3.8 3.7 5.1 7.3 3.8 4.7 5.9 9.0 8.6 5.4 4.2 2.9 5.2 5.5 4.0 4.8 7.9 9.7 8.5 16.8 11.1 5.8 8.0 8.0 5.0 11.7 9.8 5.5 5.9 8.2 7.3 6.4 3.9 13.1 14.1 3.9 7.6 13.6 0.9 6.2 9.3 9.7 5.1 6.7 6.9 6.8 6.0 4.4 7.4 9.1 10.0 9.8 3.6 8.0 6.1 2.6 8.5 5.0 6.0 11.1 6.0 6.8 4.7 8.9 6.9 16.1 9.4 3.9 4.7 10.7 11.1 5.9 9.5 2.5 12.3 6.0 8.2 12.8 8.5 9.0 10.4 6.7 10.6 0.8 1.4 1.0 0.8 0.7 1.0 0.9 0.9 0.7 0.8 1.2 1.2 0.6 0.7 0.8 0.8 1.6 0.5 4.8 7.2 3.6 9.5 9.0 4.1 2.1 3.8 2.6 3.7 4.7 5.2 8.8 9.6 9.8 33.3 10.2 6.9 4.8 6.3 7.4 11.9 10.8 6.1 24.1 12.8 7.3 12.9 8.4 9.0 7.5 19.4 3.9 5.0 2.1 6.8 6.4 7.3 6.7 9.0 71.4 7.6 6.6 10.3 15.8 6.5 7.0 7.3 9.3 30.2 11.8 15.2 51.1 12.6 8.2 11.0 6.0 1.4 4.7 8.7 7.2 14.0 9.7 14.3 6.2 36.2 37.8 6.0 6.5 7.2 11.9 6.3 13.0 12.3 12.0 11.2 13.1 10.5 9.7 27.5 10.0 9.7 10.1 19.4 10.0 7.2 12.0 4.0 LOXL1 "LOL, LOXL" ENSG00000129038 "Lysyl oxidase like 1" Q08397 15 73925989-73952137 "Disease related genes, Plasma proteins, Predicted secreted proteins" Oxidoreductase Glaucoma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 92.3;Extravillous trophoblasts: 145.8;Fibroblasts: 76.0;Smooth muscle cells: 32.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 3.4" "Lineage enriched" "Detected in single" 34 "T-cells: 3.4" "Cell line enhanced" "Detected in many" "BJ: 66.5;BJ hTERT+: 75.2;hTERT-RPE1: 73.7;U-87 MG: 61.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042111, HPA063583" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" No No 280000 "Cluster 35: T-regs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA042111: AB_10794412, HPA063583: AB_2685050" "unprognostic (6.39e-2)" "unprognostic (1.23e-1)" "unprognostic (3.05e-2)" "unprognostic (3.61e-2)" "prognostic unfavorable (9.52e-5)" "unprognostic (7.95e-2)" "unprognostic (2.49e-1)" "unprognostic (2.44e-1)" "unprognostic (3.10e-1)" "unprognostic (1.57e-1)" "unprognostic (1.63e-1)" "unprognostic (9.83e-2)" "unprognostic (1.14e-3)" "unprognostic (4.51e-2)" "unprognostic (5.81e-2)" "unprognostic (1.41e-2)" "unprognostic (9.76e-2)" 12.4 3.1 1.4 5.4 0.8 0.8 6.8 0.2 1.4 12.7 12.3 10.2 1.9 16.0 1.4 4.7 8.3 5.0 27.9 1.7 1.9 8.7 1.5 10.1 4.4 1.4 1.7 8.0 3.3 2.2 9.2 8.0 1.1 15.3 1.4 0.0 7.6 11.9 3.8 6.4 5.6 4.9 0.8 3.2 7.8 2.4 1.9 0.9 5.2 1.9 2.3 16.6 14.8 0.6 3.3 0.0 0.9 0.0 45.6 54.8 2.2 66.5 75.2 27.6 48.7 1.3 1.7 0.0 12.1 49.1 6.9 19.9 0.3 0.2 6.5 0.0 4.3 0.2 2.0 0.3 6.2 0.0 0.1 45.0 0.0 20.8 0.2 73.7 1.0 1.2 0.0 0.3 33.3 2.4 0.4 1.3 6.3 4.4 45.1 0.0 38.7 0.6 2.5 12.0 5.5 0.0 2.0 0.4 0.0 6.5 0.4 0.0 4.9 53.8 47.0 42.8 25.8 0.2 0.0 0.0 61.9 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.9 0.0 1.3 0.7 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 3.4 0.2 1.4 0.8 0.2 1.4 1.7 1.9 1.4 1.7 1.1 0.8 1.9 0.6 4.1 0.0 0.6 3.3 0.1 5.9 7.6 6.0 4.0 0.9 2.3 4.8 92.3 2.8 0.9 9.2 0.0 2.2 0.6 0.1 3.9 5.2 1.7 9.2 8.0 4.1 3.5 0.0 0.5 1.3 145.8 76.0 8.6 9.3 1.3 5.5 12.1 0.1 6.6 0.0 0.4 0.6 2.0 0.0 6.2 1.3 9.9 0.9 10.6 0.0 0.1 6.4 0.0 1.5 0.3 12.2 0.1 21.1 0.1 4.8 0.4 2.5 1.2 0.4 0.0 6.0 32.7 8.9 4.9 2.4 3.4 5.1 3.4 0.3 1.1 5.0 LPAR5 "GPR92, GPR93, KPG_010, LPA5" ENSG00000184574 "Lysophosphatidic acid receptor 5" Q9H1C0 12 6618835-6635960 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 20.9" "Cell type enhanced" "Detected in many" "B-cells: 26.5;Hofbauer cells: 38.0;Microglial cells: 33.7;Proximal enterocytes: 18.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 18.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 83.8;T-cells: 66.8" "Cell line enhanced" "Detected in many" "CAPAN-2: 10.5;HEL: 19.6;HMC-1: 26.0;K-562: 14.8;OE19: 9.4;U-698: 13.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA013170 Approved NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "HPA013170: AB_1849314" "unprognostic (1.94e-1)" "unprognostic (6.43e-2)" "unprognostic (1.78e-2)" "unprognostic (1.29e-1)" "unprognostic (1.05e-1)" "unprognostic (2.33e-1)" "unprognostic (1.37e-1)" "unprognostic (5.95e-2)" "unprognostic (3.45e-1)" "unprognostic (1.41e-2)" "unprognostic (3.62e-3)" "unprognostic (2.07e-1)" "unprognostic (6.27e-2)" "unprognostic (7.99e-3)" "unprognostic (5.43e-1)" "prognostic favorable (6.56e-5)" "unprognostic (7.43e-2)" 1.9 2.5 6.0 5.3 6.1 1.0 1.3 6.1 5.9 5.8 3.4 8.9 9.7 0.5 2.7 20.9 1.6 1.7 4.1 5.4 6.8 0.7 1.3 1.9 8.9 10.3 8.9 0.7 0.5 0.8 1.0 5.4 9.4 1.0 8.3 0.2 5.5 1.3 0.2 6.9 8.9 1.0 10.2 9.3 7.2 1.6 11.8 2.6 1.6 0.1 12.4 2.1 9.6 14.4 5.8 0.7 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.3 10.5 4.3 1.3 0.0 0.1 7.0 0.0 3.2 0.0 0.0 0.0 19.6 0.6 0.4 0.0 0.0 26.0 0.0 3.5 0.1 1.5 0.0 0.0 4.0 14.8 0.0 0.0 0.5 0.6 6.1 0.1 9.4 1.0 4.8 0.0 0.0 0.0 3.3 0.1 0.1 3.0 0.0 0.0 1.1 0.0 2.2 0.1 0.0 3.9 0.0 0.0 0.0 0.0 13.7 0.0 0.0 0.0 10.4 0.3 0.1 66.8 3.4 51.2 83.8 11.2 40.2 17.3 82.7 10.8 24.6 0.8 4.6 6.1 1.1 18.0 20.1 6.0 6.1 6.1 5.9 5.4 6.8 10.3 8.9 9.4 10.2 11.8 14.4 0.2 0.0 0.0 0.0 26.5 1.5 0.4 3.9 1.8 0.0 0.6 0.5 2.8 1.5 4.4 1.8 0.0 0.3 2.8 16.9 0.0 0.3 4.9 0.4 0.1 1.5 1.2 0.8 0.2 0.9 0.2 0.6 3.6 0.7 16.5 0.0 1.1 0.2 38.0 0.0 0.3 11.1 2.0 15.6 7.0 14.5 0.0 13.9 0.0 33.7 4.6 0.1 17.5 0.5 0.1 9.4 16.8 0.0 2.7 0.7 18.4 0.1 0.6 0.1 0.0 0.1 0.2 0.6 1.4 10.3 1.3 0.5 6.9 0.0 13.0 2.2 LPCAT3 "C3F, MBOAT5, nessy, OACT5" ENSG00000111684 "Lysophosphatidylcholine acyltransferase 3" Q6P1A2 12 6976185-7018477 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 103.5;Proximal enterocytes: 121.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 156.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (1.74e-1)" "unprognostic (3.33e-2)" "unprognostic (1.70e-1)" "unprognostic (1.57e-1)" "unprognostic (6.72e-2)" "unprognostic (3.86e-1)" "unprognostic (2.40e-2)" "unprognostic (6.90e-2)" "unprognostic (1.88e-1)" "unprognostic (5.00e-3)" "unprognostic (2.06e-1)" "unprognostic (2.58e-2)" "prognostic favorable (4.89e-5)" "unprognostic (1.13e-1)" "unprognostic (2.21e-1)" "unprognostic (6.49e-3)" "unprognostic (1.23e-1)" 36.6 52.1 8.4 21.6 9.3 28.4 36.3 11.1 9.5 20.3 10.3 51.4 123.0 18.8 21.5 32.0 21.2 18.6 37.4 8.3 9.0 44.4 109.2 46.0 17.0 11.0 9.7 17.7 50.8 19.6 15.2 38.0 9.2 35.9 47.9 4.0 37.3 16.3 45.6 34.0 99.7 21.7 9.2 20.1 58.7 11.2 9.9 21.5 27.7 57.5 21.2 35.3 21.7 9.3 20.2 34.0 15.8 44.3 109.4 51.2 32.9 11.8 49.5 31.7 53.4 78.6 103.9 21.9 6.5 19.1 65.7 50.8 19.2 43.0 24.3 52.7 21.3 44.7 28.2 71.5 23.6 23.3 45.8 81.2 24.7 30.2 15.1 20.1 30.0 33.0 24.4 15.4 20.9 30.0 29.1 28.7 53.1 73.1 20.2 29.9 21.5 22.4 38.7 156.0 13.6 12.5 68.5 107.3 7.9 49.5 10.9 31.4 12.0 19.2 27.8 34.1 8.3 19.1 14.5 30.9 24.0 23.5 17.0 44.4 55.7 91.0 21.5 80.5 25.4 12.3 22.3 24.8 37.2 12.3 20.1 21.3 53.7 32.3 98.7 21.1 29.7 38.3 8.4 9.3 11.1 9.5 8.3 9.0 11.0 9.7 9.2 9.2 9.9 9.3 17.9 70.5 38.5 15.7 13.1 23.6 39.4 35.8 36.5 5.2 19.8 13.8 0.6 12.8 30.3 20.2 0.0 103.5 11.6 47.0 11.7 29.9 2.5 18.8 21.4 13.1 43.2 57.7 20.7 33.0 51.7 14.3 49.5 26.6 14.0 10.6 15.0 62.9 41.6 11.8 16.7 26.8 26.4 21.9 9.6 1.7 18.3 15.2 7.2 6.5 15.8 12.2 15.5 25.6 22.4 18.1 27.1 6.4 17.5 24.7 121.9 37.2 16.4 4.0 19.7 6.0 18.2 24.3 35.3 17.7 22.3 66.4 18.9 17.0 41.2 25.9 LRATD1 "FAM84A, FLJ35392, NSE1" ENSG00000162981 "LRAT domain containing 1" Q96KN4 2 14632700-14650814 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 32.2;intestine: 41.0" "Group enriched" "Detected in some" 8 "Cytotrophoblasts: 162.2;Syncytiotrophoblasts: 207.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 35.0" "Group enriched" "Detected in many" 7 "amygdala: 19.7;basal ganglia: 10.8;cerebral cortex: 18.1;hippocampal formation: 13.0;white matter: 6.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 9.4;hTCEpi: 18.0;RT4: 49.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047703 Uncertain Approved Nucleoplasm NA NA "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA047703: AB_2680123" "unprognostic (1.05e-2)" "unprognostic (9.22e-2)" "unprognostic (2.24e-3)" "unprognostic (1.13e-1)" "unprognostic (4.28e-2)" "unprognostic (7.38e-2)" "unprognostic (2.62e-2)" "unprognostic (1.23e-1)" "unprognostic (1.48e-1)" "unprognostic (4.44e-2)" "unprognostic (1.20e-1)" "unprognostic (9.27e-2)" "unprognostic (3.52e-2)" "unprognostic (1.13e-1)" "unprognostic (1.58e-1)" "unprognostic (5.57e-3)" "unprognostic (1.36e-1)" 0.5 1.4 19.7 4.9 10.8 0.0 2.4 0.0 18.1 10.6 0.0 41.0 26.3 2.7 32.2 28.6 2.9 3.4 2.1 13.0 2.0 4.0 1.4 3.0 0.2 0.0 0.2 8.2 3.2 5.2 3.3 5.3 0.0 13.6 36.2 0.9 13.9 2.0 0.9 18.5 25.3 2.8 0.0 0.2 3.0 12.3 1.4 1.3 2.2 0.1 1.4 14.8 16.6 6.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.2 2.5 0.6 0.5 0.0 0.3 0.0 0.0 0.3 0.0 9.4 1.0 4.2 1.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.7 18.0 0.0 5.9 0.2 0.0 0.0 0.0 0.0 1.3 7.8 0.0 0.2 0.8 0.0 4.0 0.0 0.0 0.1 6.9 49.3 4.3 2.0 0.0 1.8 0.0 0.3 0.0 0.0 2.9 8.2 0.7 0.0 3.2 0.0 0.0 0.0 2.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.7 10.8 0.0 18.1 13.0 2.0 0.0 0.2 0.0 0.0 1.4 6.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 162.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 22.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 207.8 0.0 0.0 0.0 0.0 LRBA "BGL, CDC4L, LAB300, LBA" ENSG00000198589 "LPS responsive beige-like anchor protein" P50851 4 150264435-151015727 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 213.7;Inhibitory neurons: 192.6;Microglial cells: 161.1;Oligodendrocyte precursor cells: 239.8;Oligodendrocytes: 217.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019366, HPA023597" Approved Approved "Golgi apparatus,Cytosol" NA NA 340000 "Cluster 44: Non-specific - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" "Golgi apparatus" Cytosol "HPA019366: AB_2138441, HPA023597: AB_1853256" "unprognostic (2.60e-1)" "unprognostic (4.70e-2)" "unprognostic (1.64e-3)" "unprognostic (4.49e-3)" "unprognostic (4.38e-1)" "unprognostic (8.65e-2)" "unprognostic (5.88e-2)" "unprognostic (1.16e-1)" "unprognostic (1.09e-2)" "unprognostic (6.92e-2)" "unprognostic (2.29e-2)" "unprognostic (5.88e-2)" "prognostic favorable (2.22e-16)" "unprognostic (7.15e-2)" "unprognostic (2.36e-1)" "unprognostic (4.79e-1)" "unprognostic (3.00e-1)" 7.3 10.7 3.4 9.3 6.9 11.1 22.7 11.1 3.8 13.1 18.6 16.7 13.3 6.9 14.2 13.9 15.2 9.9 8.3 2.9 2.2 23.5 13.4 11.0 15.8 5.1 4.5 8.9 13.5 34.2 6.5 7.0 6.1 20.0 17.4 14.9 13.8 8.9 7.2 19.3 11.5 6.6 3.4 9.6 17.0 9.4 3.7 18.7 19.1 8.9 17.7 12.3 7.0 6.3 27.6 14.3 11.9 11.1 12.2 18.5 17.0 6.0 15.8 10.9 10.2 30.9 35.6 33.7 7.2 8.6 7.5 13.7 22.1 36.6 15.3 25.9 15.8 20.8 19.8 19.0 7.5 29.0 16.2 14.6 21.1 16.0 24.6 23.9 32.9 14.8 22.4 24.3 12.9 21.9 21.9 7.7 10.7 23.7 10.3 18.4 12.0 12.6 42.0 33.7 39.3 13.0 15.1 32.1 7.4 18.1 32.4 6.1 17.2 16.8 12.2 8.7 11.4 20.9 20.5 20.5 26.2 16.0 6.6 5.7 0.6 1.2 5.0 0.2 3.3 4.9 3.3 4.7 1.0 2.1 2.3 4.0 0.1 3.2 2.1 2.1 4.6 1.8 3.4 6.9 11.1 3.8 2.9 2.2 5.1 4.5 6.1 3.4 3.7 6.3 10.4 16.0 14.9 148.5 42.5 17.5 16.4 21.0 28.5 33.5 30.8 18.2 55.9 21.5 21.5 51.5 148.0 23.7 37.7 19.7 9.8 15.2 25.5 51.2 11.0 13.3 42.0 40.2 213.7 13.5 10.6 12.8 56.6 61.8 6.3 22.4 10.0 20.5 6.1 30.3 192.6 23.8 24.4 11.1 12.8 5.5 9.6 17.7 16.0 161.1 8.2 17.7 46.4 239.8 217.4 17.2 20.2 10.1 38.3 22.4 22.0 15.8 36.7 72.6 6.6 13.7 9.8 16.6 22.3 37.3 23.7 24.2 45.6 25.9 27.2 24.0 LRIG3 "FLJ90440, KIAA3016" ENSG00000139263 "Leucine rich repeats and immunoglobulin like domains 3" Q6UXM1 12 58872149-58920504 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 42.8;Basal squamous epithelial cells: 44.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 49.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010773 Approved Approved Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA010773: AB_1853275" "unprognostic (1.79e-1)" "unprognostic (2.71e-1)" "unprognostic (1.01e-2)" "unprognostic (3.88e-2)" "unprognostic (2.53e-1)" "unprognostic (3.46e-2)" "unprognostic (1.83e-2)" "unprognostic (1.34e-3)" "unprognostic (1.21e-1)" "unprognostic (1.92e-1)" "unprognostic (3.04e-2)" "unprognostic (4.25e-2)" "unprognostic (2.74e-3)" "unprognostic (2.47e-2)" "unprognostic (1.10e-1)" "unprognostic (1.28e-2)" "unprognostic (1.46e-2)" 20.8 2.6 3.5 6.7 4.3 0.1 18.8 2.6 3.3 21.0 11.2 18.6 14.2 12.5 10.6 22.3 14.3 17.7 5.3 3.7 3.0 10.3 10.3 10.4 4.3 4.2 5.4 22.4 18.9 9.1 7.1 11.5 3.4 10.5 25.6 1.8 32.9 10.4 4.0 35.9 13.4 15.4 4.5 8.7 17.9 3.3 4.1 12.2 58.2 7.8 9.6 18.6 18.5 7.6 3.9 3.6 13.6 1.0 24.2 28.0 3.1 9.2 26.4 8.7 9.3 10.9 5.0 3.7 18.3 10.3 10.5 17.9 5.1 23.3 6.3 28.1 17.8 0.9 6.3 5.4 4.7 1.6 0.4 27.9 49.8 9.3 19.8 16.9 24.1 4.2 0.2 4.5 5.8 1.8 4.5 0.1 14.4 4.6 5.5 0.0 11.5 9.2 6.7 19.8 13.8 0.0 8.1 5.0 8.6 19.0 9.3 0.2 10.4 11.8 8.1 7.1 12.2 1.9 0.0 0.0 2.5 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 4.3 2.6 3.3 3.7 3.0 4.2 5.4 3.4 4.5 4.1 7.6 17.1 16.0 24.6 17.9 0.1 22.4 8.2 42.8 44.9 3.8 6.3 10.3 3.7 34.3 23.0 1.8 0.0 0.8 0.5 24.5 0.0 11.8 0.3 8.2 37.0 16.2 11.5 0.0 1.8 18.1 0.5 19.6 23.4 4.6 0.0 0.1 12.1 7.3 2.6 3.3 6.0 11.4 16.2 0.3 8.2 1.8 27.1 0.4 3.6 9.4 0.0 3.4 0.0 3.5 22.4 7.4 15.6 29.0 1.8 4.4 8.7 4.9 14.1 0.2 6.6 10.6 11.3 0.5 2.0 25.3 22.4 0.3 1.0 15.0 31.5 4.7 LRMDA "C10orf11, CDA017, OCA7" ENSG00000148655 "Leucine rich melanocyte differentiation associated" Q9H2I8 10 75431624-76560168 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation Albinism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 61.5;epididymis: 59.5" "Cell type enhanced" "Detected in many" "Adipocytes: 42.4;Distal tubular cells: 33.2;Endometrial ciliated cells: 27.8;Hofbauer cells: 56.9;Proximal tubular cells: 113.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 57.6;eosinophil: 22.1;intermediate monocyte: 28.8;myeloid DC: 67.5;non-classical monocyte: 17.1" "Group enriched" "Detected in many" 7 "dendritic cells: 67.5;granulocytes: 22.1;monocytes: 57.6" "Cell line enhanced" "Detected in many" "Hep G2: 46.3;HMC-1: 34.0;NB-4: 65.6;SK-MEL-30: 93.0;THP-1: 48.7;U-937: 43.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047446, HPA050419" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA047446: AB_2680050, HPA050419: AB_2756316" "unprognostic (1.04e-1)" "unprognostic (8.03e-2)" "unprognostic (2.40e-1)" "unprognostic (7.97e-2)" "unprognostic (2.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.31e-1)" "unprognostic (8.57e-3)" "unprognostic (5.86e-2)" "unprognostic (6.80e-2)" "unprognostic (8.34e-2)" "unprognostic (1.26e-1)" "unprognostic (7.34e-3)" "unprognostic (7.26e-2)" "unprognostic (6.50e-2)" "unprognostic (4.98e-3)" "unprognostic (3.64e-2)" 16.1 61.5 8.0 5.4 8.6 27.5 10.3 7.7 7.7 12.0 4.7 8.1 5.8 6.4 59.5 7.5 9.7 10.2 13.3 7.8 8.4 20.6 35.8 12.8 5.2 11.5 9.6 13.0 24.9 20.6 10.1 12.7 11.8 10.7 7.2 2.4 9.2 10.0 2.7 3.1 4.5 9.0 10.2 10.5 16.8 3.7 10.9 4.1 18.6 4.8 5.1 11.4 4.5 11.5 0.3 5.7 0.2 0.1 2.9 3.5 0.1 0.7 0.0 0.3 0.5 7.6 13.4 0.0 25.8 0.0 0.1 0.3 0.0 0.0 0.1 0.5 1.6 1.6 2.9 46.3 1.1 9.4 34.0 1.4 1.0 0.6 0.1 5.5 0.8 0.1 0.0 1.4 0.1 1.0 0.1 65.6 0.3 3.9 2.2 0.1 0.2 0.1 0.6 8.3 0.3 0.4 8.1 0.0 93.0 0.2 0.5 48.7 0.9 0.3 3.1 2.4 5.3 0.4 0.2 0.2 22.6 43.6 11.3 6.4 57.6 22.1 0.1 28.8 0.3 0.1 0.0 0.0 67.5 0.1 0.1 0.1 3.2 7.1 17.1 0.5 0.2 18.9 8.0 8.6 7.7 7.7 7.8 8.4 11.5 9.6 11.8 10.2 10.9 11.5 42.4 22.4 19.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.1 5.7 0.0 0.0 3.7 12.9 0.0 1.1 0.8 0.0 33.2 16.6 0.0 27.8 2.5 13.2 0.0 0.0 0.0 15.8 0.8 4.5 0.0 10.0 7.6 16.1 0.0 0.0 56.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 0.0 0.0 6.7 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.1 0.0 0.0 113.4 6.6 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 1.2 0.6 25.7 0.0 0.0 LRP1 "A2MR, APOER, APR, CD91, IGFBP-3R, IGFBP3R1, LRP, LRP1A" ENSG00000123384 "LDL receptor related protein 1" Q07954 12 57128483-57213361 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Endocytosis "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 109.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 273.4;Hepatocytes: 188.4;Leydig cells: 233.3;Peritubular cells: 184.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "classical monocyte: 4.3;intermediate monocyte: 2.2;myeloid DC: 1.6;non-classical monocyte: 2.4" "Group enriched" "Detected in many" 21 "dendritic cells: 1.6;monocytes: 4.3" "Cell line enhanced" "Detected in many" "ASC diff: 484.8;ASC TERT1: 488.4;fHDF/TERT166: 222.2;HSkMC: 318.5;hTERT-RPE1: 248.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004182, CAB018621, HPA022903" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 180000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Nucleoplasm "CAB018621: AB_627893, HPA004182: AB_2667163, HPA022903: AB_10602426" "unprognostic (1.65e-1)" "unprognostic (1.61e-1)" "unprognostic (1.76e-1)" "unprognostic (2.71e-1)" "unprognostic (5.00e-2)" "unprognostic (4.33e-2)" "unprognostic (3.98e-1)" "unprognostic (8.68e-2)" "unprognostic (1.70e-1)" "unprognostic (3.37e-3)" "unprognostic (1.48e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (2.81e-3)" "unprognostic (6.13e-2)" "unprognostic (2.80e-2)" "prognostic unfavorable (1.29e-5)" 109.2 14.1 21.3 29.0 36.3 8.2 40.0 30.2 19.7 32.3 8.0 24.1 23.2 36.9 6.2 19.3 30.3 31.5 35.5 16.7 21.9 5.7 35.0 34.0 4.9 46.0 31.5 71.0 10.7 7.8 10.2 39.8 27.9 13.8 11.2 9.9 20.3 20.2 13.0 20.4 18.4 28.9 27.1 13.6 15.1 7.3 48.9 5.6 17.6 23.5 2.7 25.5 29.3 27.6 7.7 14.5 30.4 24.2 484.8 488.4 91.2 85.3 109.0 27.5 26.7 26.9 12.4 0.4 10.4 222.2 6.0 33.6 5.3 8.7 9.7 0.7 1.3 0.4 17.9 56.4 66.5 0.5 14.6 318.5 3.1 61.8 7.2 248.7 1.7 1.1 0.4 1.3 87.2 1.7 0.2 0.4 34.8 11.0 8.8 3.2 171.0 1.6 1.9 2.2 1.4 16.4 19.0 0.6 13.2 42.0 2.9 1.2 1.2 96.0 35.0 53.9 5.2 1.1 0.1 0.2 167.4 0.1 18.7 0.0 4.3 0.0 0.0 2.2 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.0 1.6 21.3 36.3 30.2 19.7 16.7 21.9 46.0 31.5 27.9 27.1 48.9 27.6 24.6 12.8 8.4 113.6 3.2 24.0 11.9 28.7 19.9 29.2 4.9 19.3 14.8 15.7 14.7 1.8 0.0 87.5 1.1 81.7 0.0 7.4 1.9 9.7 111.4 13.0 4.2 0.8 39.3 1.8 53.0 273.4 49.5 4.2 6.3 36.9 11.0 188.4 73.8 8.4 41.6 14.1 6.1 145.3 28.6 8.4 233.3 102.9 28.4 89.9 48.8 154.7 1.0 173.4 6.6 14.7 27.2 184.3 4.4 5.5 86.0 2.1 15.1 7.3 39.5 129.7 77.0 1.6 2.4 35.4 16.1 125.9 4.2 11.4 25.0 12.3 LRRC25 "FLJ38116, MAPA" ENSG00000175489 "Leucine rich repeat containing 25" Q8N386 19 18391137-18397622 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 32.4;lymphoid tissue: 61.2" "Group enriched" "Detected in some" 6 "Hofbauer cells: 47.0;Kupffer cells: 123.6;Macrophages: 90.0;monocytes: 74.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 320.6;eosinophil: 356.2;intermediate monocyte: 512.1;myeloid DC: 229.3;neutrophil: 573.0;non-classical monocyte: 706.7" "Group enriched" "Detected in all" 60 "dendritic cells: 229.3;granulocytes: 573.0;monocytes: 706.7" "Cell line enhanced" "Detected in some" "Hep G2: 1.0;HMC-1: 1.8;THP-1: 1.7;U-937: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029459 Approved Approved "Endoplasmic reticulum,Microtubules,Cytosol" NA NA 630000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Endoplasmic reticulum, Microtubules, Cytosol" "HPA029459: AB_10610005" "unprognostic (2.72e-2)" "unprognostic (6.08e-2)" "unprognostic (1.76e-2)" "unprognostic (2.07e-1)" "unprognostic (3.77e-2)" "unprognostic (9.15e-2)" "unprognostic (5.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-2)" "unprognostic (4.63e-2)" "unprognostic (2.02e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-3)" "unprognostic (5.77e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (1.74e-1)" "unprognostic (1.14e-1)" 9.4 9.4 2.4 21.8 2.5 32.4 3.1 3.3 2.9 1.8 3.2 3.3 3.7 1.6 0.7 2.3 3.9 5.3 2.5 2.3 3.1 2.4 5.9 11.5 9.9 4.6 4.0 1.5 2.0 0.7 1.2 5.4 4.2 2.0 2.8 0.3 2.6 1.2 3.7 1.0 4.8 6.7 2.8 61.2 2.3 1.2 5.4 3.0 1.2 8.7 4.0 7.0 1.3 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.3 1.0 0.8 0.4 1.8 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.4 0.2 0.1 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.7 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.2 1.5 0.1 55.4 320.6 356.2 0.9 512.1 1.9 7.3 0.6 0.7 229.3 8.4 0.5 0.6 573.0 4.6 706.7 32.1 1.3 229.2 2.4 2.5 3.3 2.9 2.3 3.1 4.6 4.0 4.2 2.8 5.4 4.7 0.7 0.0 1.3 0.0 5.0 0.0 0.1 0.1 0.0 0.1 0.3 1.0 0.3 0.0 0.7 0.0 0.0 0.1 2.9 0.1 5.9 0.1 1.9 0.2 0.1 0.9 0.0 2.1 0.1 0.0 0.4 0.5 0.0 0.4 10.2 0.0 1.8 0.5 47.0 0.0 0.1 0.0 0.0 123.6 12.5 0.5 0.0 90.0 1.8 1.0 74.9 0.0 6.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 2.4 0.2 0.0 0.2 0.0 0.1 0.4 1.1 0.2 0.1 0.1 LRRC32 "D11S833E, GARP" ENSG00000137507 "Leucine rich repeat containing 32" Q14392 11 76657524-76670747 "Predicted intracellular proteins, Predicted membrane proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 78.0;Endothelial cells: 88.3;Extravillous trophoblasts: 164.2;Hepatic stellate cells: 95.3;Sertoli cells: 39.5;Smooth muscle cells: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 2.2" "Lineage enhanced" "Detected in single" "T-cells: 2.2" "Group enriched" "Detected in some" 6 "ASC diff: 115.0;ASC TERT1: 70.3;HSkMC: 44.0;HUVEC TERT2: 51.4;U-2197: 108.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055775, HPA058434" Enhanced Nucleoplasm "Intracellular and membrane" NA NA 98000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA055775: AB_2732600, HPA058434: AB_2732622" "unprognostic (3.18e-1)" "unprognostic (1.38e-1)" "unprognostic (2.60e-2)" "unprognostic (4.19e-3)" "unprognostic (1.16e-1)" "unprognostic (8.84e-2)" "unprognostic (1.39e-2)" "unprognostic (2.24e-2)" "unprognostic (6.29e-2)" "unprognostic (1.83e-2)" "unprognostic (1.58e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (3.93e-5)" "unprognostic (7.99e-3)" "unprognostic (1.15e-2)" "unprognostic (5.22e-3)" "prognostic unfavorable (2.64e-4)" 104.5 34.3 12.6 10.5 12.6 2.4 63.6 11.2 11.8 56.2 8.4 23.2 8.9 36.4 6.2 10.3 31.6 29.0 55.7 9.6 10.6 64.7 11.3 109.0 4.3 12.2 13.8 13.5 12.0 7.5 16.7 53.0 13.0 24.9 6.1 1.3 12.8 11.0 23.6 26.6 21.4 15.2 10.9 28.9 21.3 3.6 15.0 2.0 42.3 6.2 1.5 36.7 28.8 11.5 0.0 0.0 1.3 0.0 115.0 70.3 1.4 0.4 0.8 0.1 0.1 0.0 0.0 0.2 3.1 1.9 0.0 0.1 0.2 0.0 0.1 0.0 0.0 11.8 0.6 0.0 2.2 0.0 0.1 44.0 0.0 4.1 0.2 0.9 51.4 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 7.6 0.2 0.0 13.8 7.5 0.8 108.3 0.0 0.1 0.0 1.9 5.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.2 4.3 12.6 12.6 11.2 11.8 9.6 10.6 12.2 13.8 13.0 10.9 15.0 11.5 78.0 0.0 4.3 0.0 1.7 14.5 0.3 0.0 1.8 0.0 0.6 0.6 10.4 0.0 1.3 0.0 0.0 1.9 0.1 0.2 0.0 0.3 1.3 0.1 1.9 88.3 0.0 5.3 0.0 0.0 164.2 26.4 0.5 0.3 2.5 0.5 95.3 0.6 3.6 0.0 0.1 0.4 0.0 3.1 19.0 1.9 9.0 2.9 17.8 14.0 0.0 0.4 0.0 0.0 0.1 0.0 2.2 9.1 0.2 1.4 0.0 0.4 0.7 0.1 39.5 2.1 47.6 0.4 4.7 0.6 12.5 8.3 1.6 0.4 0.1 1.2 LRRC7 "densin-180, KIAA1365" ENSG00000033122 "Leucine rich repeat containing 7" 1 69567922-70151945 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 20.2" "Group enriched" "Detected in many" 20 "Excitatory neurons: 1132.4;Inhibitory neurons: 996.9;Oligodendrocyte precursor cells: 1038.0;Oligodendrocytes: 408.2" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "amygdala: 6.9;basal ganglia: 17.0;cerebral cortex: 20.2;hippocampal formation: 17.7;thalamus: 11.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HaCaT: 12.6;HEL: 44.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA005625 Supported "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Nucleoplasm, Centrosome" "HPA005625: AB_1853340" "unprognostic (2.81e-2)" "unprognostic (1.62e-2)" "unprognostic (1.51e-1)" "unprognostic (2.98e-3)" "unprognostic (2.47e-1)" "unprognostic (1.73e-1)" "unprognostic (1.04e-1)" "unprognostic (3.50e-2)" "unprognostic (4.84e-3)" "unprognostic (2.92e-2)" "unprognostic (1.06e-3)" "unprognostic (1.46e-1)" "unprognostic (5.64e-6)" "unprognostic (1.31e-2)" "unprognostic (1.74e-2)" "unprognostic (5.13e-3)" "unprognostic (2.08e-3)" 0.1 0.2 6.9 0.1 17.0 0.2 0.0 0.0 20.2 0.2 0.0 0.4 0.1 0.2 0.1 0.2 0.0 1.0 1.4 17.7 1.7 0.8 0.2 0.0 0.1 0.0 2.2 0.1 0.8 0.1 0.0 0.2 0.0 0.3 0.6 1.5 0.0 0.1 1.0 0.2 0.2 0.2 0.0 0.0 0.2 1.6 11.4 0.0 2.2 0.0 0.0 0.1 0.1 2.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.4 4.4 0.0 0.0 12.6 0.3 0.0 0.0 0.0 0.6 44.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 4.7 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.1 0.0 0.0 0.0 0.0 6.9 17.0 0.0 20.2 17.7 1.7 0.0 2.2 0.0 0.0 11.4 2.9 0.8 0.0 0.0 41.4 2.5 0.8 0.6 0.4 1.8 44.4 0.3 0.3 6.2 2.8 0.2 0.0 2.1 0.4 2.4 0.0 0.0 0.0 29.4 0.5 1.4 1.2 0.0 3.2 1132.4 0.0 0.5 1.8 0.0 1.4 0.0 0.6 2.9 6.5 0.3 6.7 996.9 0.0 0.0 2.8 3.6 6.3 0.6 0.5 5.4 17.8 1.7 1.0 2.1 1038.0 408.2 0.0 0.0 3.0 1.3 0.9 0.0 1.6 0.1 8.3 0.0 1.4 1.5 9.2 3.0 0.5 1.3 0.1 2.3 0.1 0.0 0.1 LRRC75A "C17orf76, FAM211A, FLJ35696" ENSG00000181350 "Leucine rich repeat containing 75A" Q8NAA5 17 16441577-16492193 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 47.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 62.1;SK-MEL-30: 21.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028528, HPA065840" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 36: HEL - Hemostasis" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nucleoli, Cytosol" "HPA028528: AB_10600755, HPA065840: " "unprognostic (1.09e-1)" "unprognostic (5.60e-2)" "unprognostic (5.79e-2)" "unprognostic (3.85e-5)" "unprognostic (3.93e-2)" "unprognostic (3.23e-2)" "unprognostic (3.44e-1)" "unprognostic (7.66e-3)" "unprognostic (7.74e-2)" "unprognostic (2.84e-1)" "prognostic favorable (7.46e-5)" "unprognostic (8.36e-2)" "unprognostic (4.28e-3)" "unprognostic (8.84e-2)" "unprognostic (1.82e-1)" "unprognostic (1.17e-3)" "unprognostic (2.06e-1)" 5.5 21.5 6.8 6.4 5.0 16.1 0.5 1.8 7.7 1.3 0.1 20.2 47.4 4.0 0.2 2.1 1.3 3.1 2.4 6.8 6.5 2.0 0.6 4.6 5.6 4.1 6.7 4.4 7.0 4.7 3.1 3.4 5.1 1.9 9.0 2.3 1.3 1.1 2.9 2.2 44.0 2.3 3.4 21.5 7.4 10.6 5.1 0.5 4.9 0.6 1.6 1.5 0.5 5.3 8.9 6.3 7.6 6.0 0.2 0.2 1.3 2.4 0.4 1.8 1.5 7.9 2.6 0.6 6.6 0.2 3.7 3.7 0.2 0.0 0.0 3.4 6.5 62.1 3.9 0.0 0.3 1.5 7.3 0.0 0.0 0.4 0.0 3.2 2.3 9.4 3.9 1.7 0.1 12.8 15.3 6.7 1.7 20.3 0.7 5.8 5.5 0.8 0.4 1.8 16.6 4.6 0.6 1.8 21.7 3.3 1.4 1.4 0.0 2.2 10.5 6.7 11.9 12.2 2.6 2.0 0.8 5.1 7.0 0.0 0.5 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.7 0.3 0.4 1.0 0.0 0.0 0.4 6.8 5.0 1.8 7.7 6.8 6.5 4.1 6.7 5.1 3.4 5.1 5.3 40.5 41.7 69.7 10.7 21.6 0.0 9.6 0.0 2.2 9.1 24.9 13.3 0.7 14.3 19.8 1.8 6.2 16.1 24.8 52.5 19.6 3.9 7.1 30.0 61.0 14.7 24.7 9.7 5.3 7.1 20.4 30.5 2.0 58.7 29.7 25.0 11.0 10.0 12.0 3.3 3.6 52.2 0.0 13.9 0.0 8.0 16.4 22.9 0.0 1.0 7.7 21.3 2.1 4.0 4.2 6.2 36.0 11.3 12.0 8.7 65.4 19.4 8.7 18.2 13.1 22.9 19.4 8.0 6.5 1.1 0.0 16.7 18.6 66.3 66.0 7.5 LRRC75B "C22orf36, FAM211B, MGC131773" ENSG00000178026 "Leucine rich repeat containing 75B" Q2VPJ9 22 24585620-24593208 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 34.3;Hepatocytes: 25.6;Muller glia cells: 39.9;Proximal enterocytes: 46.7;Proximal tubular cells: 44.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 5.3;MCF7: 5.0;SH-SY5Y: 4.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002540 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "HPA002540: AB_1079263" "unprognostic (1.21e-1)" "unprognostic (2.00e-1)" "unprognostic (2.47e-1)" "unprognostic (2.34e-1)" "unprognostic (2.74e-2)" "unprognostic (5.21e-2)" "unprognostic (4.52e-2)" "unprognostic (2.48e-2)" "unprognostic (2.49e-1)" "unprognostic (2.48e-2)" "unprognostic (2.67e-2)" "unprognostic (1.35e-1)" "unprognostic (1.47e-1)" "unprognostic (1.74e-1)" "unprognostic (1.28e-1)" "unprognostic (7.40e-2)" "unprognostic (9.69e-2)" 1.8 0.7 5.8 0.0 5.5 0.3 1.8 5.7 7.4 1.9 3.6 3.2 0.0 1.0 0.5 2.1 1.5 0.0 2.9 5.2 6.0 5.6 3.6 0.8 0.0 6.0 6.1 3.2 3.5 0.0 1.3 0.1 5.7 2.8 0.1 0.6 2.0 0.4 2.5 1.8 1.6 0.0 5.9 0.5 2.5 7.5 5.9 0.1 1.6 0.0 0.1 3.5 1.9 5.8 0.1 2.8 0.0 1.5 0.3 1.1 0.2 0.4 0.4 0.9 1.0 2.0 0.0 0.0 0.7 0.8 0.8 3.0 0.2 1.5 0.0 0.9 1.8 0.2 0.3 5.3 2.6 0.0 0.0 0.0 1.1 1.0 0.1 0.5 0.7 0.0 0.1 0.0 0.1 5.0 0.0 1.0 1.3 3.4 1.1 0.0 0.1 0.0 1.2 0.3 1.4 4.2 1.4 0.4 0.5 0.3 0.0 0.5 1.5 1.6 0.9 0.6 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 5.8 5.5 5.7 7.4 5.2 6.0 6.0 6.1 5.7 5.9 5.9 5.8 1.6 12.8 5.9 9.4 0.3 0.0 2.5 0.0 2.2 2.8 16.2 18.7 4.4 34.3 0.0 7.3 0.0 2.5 0.9 10.7 11.7 9.8 1.6 2.3 3.6 1.8 1.2 1.3 3.8 8.9 0.4 7.1 14.3 6.1 0.0 7.2 2.9 25.6 1.1 1.7 4.1 8.0 0.0 1.6 0.0 7.9 12.8 1.4 0.0 1.0 0.3 39.9 0.0 7.1 2.2 4.0 6.2 9.8 0.6 8.0 46.7 44.5 0.0 1.8 0.0 4.5 4.2 0.5 1.3 2.5 0.0 1.1 0.8 2.0 6.4 1.3 LRRK2 "DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2" ENSG00000188906 "Leucine rich repeat kinase 2" Q5S007 12 40196744-40369285 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Differentiation" "GTPase activation, Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lung: 52.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 502.2;Excitatory neurons: 92.0;monocytes: 133.1;Oligodendrocyte precursor cells: 256.9" "Cancer enhanced" "Detected in many" "renal cancer: 17.1;thyroid cancer: 22.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 8 "neutrophil: 58.2" "Lineage enriched" "Detected in many" 8 "granulocytes: 58.2" "Cell line enhanced" "Detected in some" "A549: 4.6;ASC TERT1: 5.6;BJ hTERT+: 3.2;RPTEC TERT1: 7.8;T-47d: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014293, CAB037160" Approved Supported Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" Vesicles "CAB037160: AB_1840989, HPA014293: AB_1853353" "unprognostic (2.67e-1)" "unprognostic (1.75e-1)" "unprognostic (6.45e-3)" "unprognostic (1.06e-1)" "unprognostic (3.00e-2)" "unprognostic (6.10e-3)" "unprognostic (2.71e-1)" "unprognostic (3.14e-1)" "unprognostic (2.25e-1)" "unprognostic (9.07e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "prognostic favorable (3.02e-6)" "unprognostic (2.55e-2)" "unprognostic (3.43e-2)" "unprognostic (2.01e-3)" "unprognostic (5.21e-3)" 4.8 3.1 1.1 10.1 1.9 9.0 2.6 0.9 2.1 5.1 1.2 4.3 0.6 4.8 1.9 7.0 4.1 6.2 3.9 1.3 1.1 10.9 5.6 52.4 6.8 1.7 1.1 5.4 3.6 8.4 2.1 1.2 1.4 2.6 1.8 1.5 3.5 2.0 5.5 2.1 3.6 4.0 1.1 10.8 2.1 0.8 1.2 2.5 2.9 7.9 5.4 4.5 5.5 1.9 0.0 4.6 0.0 0.0 2.3 5.6 0.0 1.3 3.2 0.1 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.1 0.0 0.6 0.4 0.0 2.1 0.4 0.0 0.0 2.5 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.3 0.0 0.5 2.7 0.1 3.1 1.5 1.0 0.4 0.5 0.6 0.4 0.0 0.0 0.0 1.3 0.0 1.7 0.0 7.2 2.2 0.0 5.2 0.0 1.8 0.0 0.0 2.1 1.7 0.0 0.0 58.2 0.0 6.9 0.3 0.0 1.3 1.1 1.9 0.9 2.1 1.3 1.1 1.7 1.1 1.4 1.1 1.2 1.9 7.4 32.1 502.2 17.3 29.9 2.4 1.8 0.4 2.8 8.6 1.3 1.4 7.8 5.7 17.3 27.6 0.0 0.0 1.9 0.0 1.9 1.3 0.5 0.4 2.6 7.0 0.0 2.1 92.0 2.7 0.1 16.1 0.5 0.4 13.9 2.7 13.2 8.2 4.6 47.1 28.0 0.0 0.0 55.8 8.7 1.2 19.0 52.2 12.4 73.1 133.1 8.6 3.1 256.9 3.1 0.8 1.1 12.0 2.8 0.6 0.0 22.5 3.4 1.0 0.0 22.5 4.8 0.3 1.0 12.6 3.1 0.4 3.4 11.2 0.0 0.7 LSAMP "IGLON3, LAMP" ENSG00000185565 "Limbic system associated membrane protein" Q13449 3 115802363-117139389 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.9;retina: 41.3" "Group enriched" "Detected in many" 9 "Astrocytes: 3381.0;Excitatory neurons: 1001.8;Inhibitory neurons: 2137.4;Oligodendrocyte precursor cells: 2480.6;Oligodendrocytes: 933.9" "Cancer enhanced" "Detected in many" "glioma: 13.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 11.0;SH-SY5Y: 22.5;WM-115: 55.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054051, HPA076122" Enhanced Cytosol NA NA 150000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 58: Brain - Synaptic function" "Cluster 17: WM-115 - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol "HPA054051: AB_2682358, HPA076122: AB_2686779" "unprognostic (4.18e-2)" "unprognostic (2.54e-1)" "unprognostic (9.97e-3)" "unprognostic (6.03e-2)" "unprognostic (9.63e-2)" "unprognostic (4.15e-3)" "unprognostic (6.81e-2)" "unprognostic (2.70e-2)" "unprognostic (5.71e-2)" "unprognostic (6.82e-3)" "unprognostic (1.26e-1)" "unprognostic (6.03e-2)" "unprognostic (1.92e-2)" "unprognostic (1.28e-2)" "unprognostic (1.06e-1)" "unprognostic (5.23e-5)" "unprognostic (1.31e-2)" 3.1 15.7 47.8 5.6 45.4 1.0 1.7 22.6 73.9 21.8 0.0 9.9 2.0 5.0 3.1 3.9 3.1 13.5 2.3 64.2 36.3 2.6 0.8 10.6 4.9 37.5 32.2 5.5 14.4 8.9 3.8 1.0 37.8 26.1 3.8 41.3 1.2 7.3 0.2 5.1 2.6 3.8 28.5 1.9 3.8 4.6 56.4 1.2 5.0 0.2 6.7 6.5 4.8 31.9 0.2 3.2 11.0 0.3 1.1 3.4 1.1 1.0 0.5 0.4 1.1 0.2 0.7 0.8 0.2 6.0 0.3 0.2 0.2 0.1 0.5 0.5 0.1 0.3 1.0 0.3 0.2 0.8 0.5 2.8 0.0 1.3 0.1 0.2 0.1 1.3 0.4 1.2 0.0 0.3 1.3 0.8 4.1 0.1 0.9 0.2 0.2 0.2 2.8 1.1 2.4 22.5 0.0 0.2 3.5 4.5 0.3 0.8 0.0 2.0 1.5 2.7 0.6 1.3 1.2 0.3 0.4 0.3 55.9 0.9 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.3 0.2 0.1 0.4 0.0 0.1 0.1 0.1 0.0 47.8 45.4 22.6 73.9 64.2 36.3 37.5 32.2 37.8 28.5 56.4 31.9 0.5 0.0 1.1 3381.0 0.6 7.6 0.3 0.0 0.0 54.2 1.2 0.4 25.5 4.3 0.6 0.0 2.1 0.2 0.0 0.0 0.0 0.0 22.5 0.9 26.5 5.8 0.0 0.0 1001.8 3.6 0.0 25.0 2.6 1.1 0.0 20.1 4.2 0.0 0.3 220.4 2137.4 0.0 0.0 0.0 3.2 22.2 126.2 1.9 56.9 111.5 0.0 126.9 0.0 2480.6 933.9 0.4 0.0 91.7 1.0 18.3 0.0 0.2 0.0 11.3 0.0 0.1 4.0 0.9 0.5 0.6 5.1 0.0 0.4 4.9 0.0 0.6 LTB "p33, TNFC, TNFSF3" ENSG00000227507 "Lymphotoxin beta" Q06643 6 31580525-31582522 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 66.7;lymphoid tissue: 229.2" "Cell type enhanced" "Detected in many" "B-cells: 1087.8;dendritic cells: 183.5;Ductal cells: 280.4;Pancreatic endocrine cells: 296.2;T-cells: 554.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "CAPAN-2: 35.6;Daudi: 127.4;HDLM-2: 82.2;HMC-1: 38.1;NB-4: 62.3;REH: 58.6;U-698: 90.8" "Not detected" "Not detected" HPA048884 Approved Approved Centrosome NA NA "Cluster 30: Non-specific - Translation" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Centrosome "HPA048884: AB_2680543" "unprognostic (1.43e-2)" "unprognostic (3.89e-2)" "unprognostic (7.29e-2)" "prognostic favorable (2.36e-6)" "unprognostic (2.91e-3)" "prognostic favorable (1.74e-4)" "unprognostic (1.45e-1)" "unprognostic (9.49e-3)" "unprognostic (1.42e-3)" "unprognostic (4.26e-2)" "unprognostic (4.52e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.31e-7)" "unprognostic (8.91e-2)" "unprognostic (4.92e-2)" "unprognostic (6.56e-3)" "unprognostic (1.99e-1)" 3.5 0.7 0.2 82.6 0.3 19.1 1.3 0.1 0.5 1.3 0.2 6.7 8.2 1.2 0.0 4.3 1.2 4.8 1.1 0.1 0.2 10.3 4.8 8.7 103.9 0.4 0.2 0.4 2.5 0.2 0.7 0.9 0.3 2.4 2.7 0.0 4.2 0.3 1.0 2.2 66.7 1.9 0.2 229.2 13.9 0.2 0.3 83.3 3.8 1.4 47.6 8.7 1.4 0.2 18.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 35.6 127.4 1.8 0.0 0.2 0.0 0.0 0.0 0.0 82.2 0.0 1.4 0.0 0.0 0.0 0.4 38.1 0.0 0.0 0.0 0.3 0.0 0.6 0.8 0.0 0.0 0.0 0.0 18.5 62.3 0.0 0.0 0.0 58.6 0.0 11.4 32.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.7 0.0 0.0 0.5 0.0 0.0 0.0 0.8 90.8 0.0 0.0 0.0 79.2 9.2 542.5 95.7 55.9 646.7 1027.3 924.3 419.4 14.5 1021.9 713.6 317.0 327.8 142.5 94.5 412.0 672.0 308.9 0.2 0.3 0.1 0.5 0.1 0.2 0.4 0.2 0.3 0.2 0.3 0.2 3.0 0.0 9.0 1.3 1087.8 16.3 0.5 45.7 2.2 0.7 2.9 3.7 0.5 2.8 4.7 90.1 0.0 0.9 183.5 0.9 1.9 280.4 3.5 2.2 2.0 8.4 0.0 11.2 0.9 113.1 0.3 6.3 3.1 1.5 14.0 0.1 10.8 3.5 10.1 0.0 0.9 0.4 160.7 31.0 112.1 0.2 0.6 49.8 42.7 0.0 72.3 1.8 99.9 0.0 0.3 296.2 1.6 0.0 13.6 3.0 0.0 11.6 0.9 0.2 6.6 1.3 4.3 0.4 1.2 1.2 12.4 0.3 554.0 0.3 3.6 0.3 LTK TYK1 ENSG00000062524 "Leukocyte receptor tyrosine kinase" P29376 15 41503637-41513887 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.2;lung: 15.1;salivary gland: 11.8" "Cell type enhanced" "Detected in some" "Distal enterocytes: 25.3;Gastric mucus-secreting cells: 18.8;Hepatic stellate cells: 11.4;Intestinal goblet cells: 7.9;Proximal enterocytes: 15.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "MAIT T-cell: 5.7;plasmacytoid DC: 5.0" "Group enriched" "Detected in many" 10 "dendritic cells: 5.0;T-cells: 5.7" "Cell line enhanced" "Detected in some" "HEL: 5.0;NB-4: 9.7;RH-30: 4.6;THP-1: 14.7" "Low region specificity" "Detected in many" HPA059545 Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA059545: AB_2684057" "unprognostic (9.47e-4)" "unprognostic (5.52e-4)" "unprognostic (1.51e-1)" "unprognostic (2.49e-1)" "unprognostic (4.12e-1)" "unprognostic (5.65e-3)" "unprognostic (1.74e-2)" "unprognostic (7.22e-2)" "unprognostic (2.89e-2)" "unprognostic (2.81e-3)" "unprognostic (9.36e-3)" "unprognostic (5.36e-2)" "unprognostic (4.68e-2)" "unprognostic (5.78e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.90e-1)" 0.8 0.6 1.0 1.4 1.6 4.6 0.5 1.2 1.8 0.9 0.6 5.2 12.5 0.2 0.0 0.3 0.4 2.4 1.7 1.3 0.7 4.0 2.9 15.1 1.2 0.6 0.6 0.1 0.3 0.6 0.7 10.4 0.7 0.4 5.7 0.1 11.8 0.3 1.8 1.4 13.2 0.3 0.6 5.5 9.9 2.5 0.8 0.4 0.7 0.0 2.1 0.7 0.7 0.9 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.1 0.6 0.8 1.2 2.2 0.0 0.0 0.0 0.6 0.0 0.0 2.6 0.0 0.4 0.2 1.3 5.0 0.1 0.0 2.0 0.0 0.0 0.3 0.4 0.0 0.1 0.0 0.0 0.0 1.9 0.0 1.8 0.0 0.0 9.7 0.4 1.8 0.2 0.2 4.6 0.1 0.0 0.0 0.4 2.9 0.1 0.2 0.0 2.6 0.2 14.7 0.0 0.0 0.2 0.1 0.0 0.3 0.2 0.2 0.0 0.5 0.8 0.0 0.0 0.0 0.4 0.0 5.7 0.5 0.3 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.1 1.0 1.6 1.2 1.8 1.3 0.7 0.6 0.6 0.7 0.6 0.8 0.9 0.3 0.0 0.0 0.3 1.6 0.1 0.0 0.4 0.0 0.0 0.2 0.1 0.8 2.8 0.9 0.0 0.0 0.3 5.5 25.3 0.0 0.0 2.8 0.1 0.4 1.8 1.8 3.2 2.9 0.2 1.5 0.2 18.8 0.2 0.0 0.3 11.4 0.5 0.1 0.0 0.2 7.9 0.0 1.9 0.6 2.1 0.0 0.4 3.6 0.0 0.4 0.0 1.0 0.5 0.4 0.7 5.5 0.0 2.7 0.0 15.3 0.0 5.6 0.0 0.0 0.3 0.5 2.2 1.2 0.0 0.1 0.4 4.0 0.0 3.8 0.0 LUZP1 LUZP ENSG00000169641 "Leucine zipper protein 1" Q86V48 1 23084023-23177808 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 349.1;Early spermatids: 291.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 39.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 127.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028506, HPA028542" Enhanced Approved "Actin filaments" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" "HPA028506: AB_10600083, HPA028542: AB_10601986" "unprognostic (3.04e-2)" "prognostic unfavorable (5.57e-4)" "unprognostic (7.35e-3)" "unprognostic (7.20e-2)" "unprognostic (3.96e-2)" "unprognostic (8.27e-2)" "unprognostic (8.46e-3)" "unprognostic (9.77e-3)" "unprognostic (7.34e-2)" "unprognostic (2.56e-3)" "unprognostic (1.19e-1)" "unprognostic (3.50e-1)" "prognostic favorable (1.46e-7)" "unprognostic (4.49e-1)" "unprognostic (2.09e-1)" "unprognostic (2.51e-1)" "unprognostic (1.33e-1)" 11.5 14.3 6.0 9.2 8.1 14.2 7.3 6.3 24.6 10.1 4.1 13.1 22.7 11.9 5.4 9.3 6.3 13.0 13.6 7.6 10.9 10.7 3.6 10.4 6.4 13.7 8.1 7.6 6.1 20.1 3.8 12.7 13.9 9.8 13.2 5.4 6.9 9.6 3.3 8.9 24.7 12.8 5.1 10.7 5.2 11.4 12.3 9.8 9.5 6.6 7.1 10.4 7.4 11.0 26.4 17.7 24.5 28.5 24.6 31.3 17.8 25.3 40.1 31.0 32.4 10.1 12.0 0.5 22.6 43.0 19.9 34.8 24.5 68.5 37.6 9.6 16.2 36.6 21.8 9.6 16.2 18.5 22.5 27.7 26.4 45.6 35.6 25.6 70.6 10.0 13.6 2.0 25.2 7.0 12.6 7.9 20.8 8.1 18.9 18.9 36.7 3.1 14.0 17.1 4.5 11.6 60.4 16.8 20.3 48.9 9.6 9.6 127.0 36.2 27.2 27.2 25.4 3.0 7.8 9.8 15.9 29.8 31.8 39.8 7.6 8.4 11.5 5.4 13.1 3.2 8.7 7.5 7.6 5.8 6.9 6.9 4.1 7.1 10.9 15.8 5.1 3.3 6.0 8.1 6.3 24.6 7.6 10.9 13.7 8.1 13.9 5.1 12.3 11.0 103.5 9.6 14.1 58.1 17.1 135.2 349.1 64.7 117.8 23.7 31.3 41.7 54.7 27.1 33.7 20.2 2.1 25.6 34.1 100.3 15.6 58.6 291.4 35.6 83.0 138.2 21.5 9.5 113.2 30.6 53.7 49.4 14.3 54.1 22.8 21.9 68.6 11.5 27.3 21.9 111.3 55.8 61.1 18.0 77.9 52.9 36.4 36.4 33.8 65.6 83.7 17.4 33.0 38.2 7.2 75.9 54.0 43.6 19.5 83.5 117.3 23.3 24.0 8.4 32.9 43.7 67.5 84.6 85.9 72.9 70.8 24.8 46.3 38.4 54.9 183.0 LXN ENSG00000079257 Latexin Q9BS40 3 158645822-158672648 "Predicted intracellular proteins" "Inflammatory response" "Heparin-binding, Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 97.7" "Cell type enhanced" "Detected in many" "granulocytes: 123.0;Respiratory ciliated cells: 120.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 4 "hTERT-RPE1: 1196.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014179, CAB025128" Enhanced Approved Nucleoplasm,Cytosol No NA 4700000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 60: Granulocytes - Receptor signaling" "Nucleoplasm, Cytosol" "CAB025128: , HPA014179: AB_1853404" "unprognostic (4.46e-2)" "unprognostic (2.59e-1)" "unprognostic (1.80e-2)" "unprognostic (2.42e-2)" "unprognostic (1.36e-1)" "unprognostic (3.20e-2)" "unprognostic (3.20e-1)" "unprognostic (5.82e-3)" "unprognostic (4.70e-3)" "unprognostic (1.98e-1)" "unprognostic (7.13e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.86e-5)" "unprognostic (8.45e-2)" "unprognostic (3.48e-2)" "unprognostic (3.18e-1)" "unprognostic (8.84e-2)" 59.0 47.0 3.7 21.5 6.4 27.1 22.4 7.3 4.4 20.3 14.1 42.0 30.3 13.7 23.7 9.9 34.3 40.5 23.1 4.5 5.4 21.6 5.6 26.3 18.6 3.9 4.3 49.7 14.1 14.0 16.0 22.0 4.1 36.9 44.0 3.6 42.4 17.9 5.4 12.4 26.1 22.9 3.6 10.2 15.0 4.5 6.2 13.8 18.3 7.8 14.3 97.7 14.4 4.2 0.1 40.7 3.1 0.5 17.0 58.2 3.4 31.3 80.4 7.6 15.2 0.1 91.3 0.3 28.2 8.7 0.2 14.1 8.1 12.7 11.2 0.1 40.2 19.6 33.0 0.4 19.5 5.0 0.5 131.5 2.3 14.5 2.4 1196.4 296.5 0.1 0.3 0.9 0.0 167.0 2.1 0.0 3.6 7.3 10.5 5.5 0.0 40.0 27.6 113.4 5.1 0.1 0.0 42.5 10.4 9.4 0.3 0.1 42.8 0.3 0.3 42.3 0.1 0.6 0.0 0.2 14.8 1.6 0.5 28.8 5.8 8.6 5.6 5.8 5.8 10.3 11.7 9.3 7.3 6.9 12.9 7.2 36.7 9.8 3.6 7.6 29.8 6.5 3.7 6.4 7.3 4.4 4.5 5.4 3.9 4.3 4.1 3.6 6.2 4.2 71.0 16.0 9.2 0.3 4.4 5.6 84.1 27.0 4.6 0.3 17.3 21.2 3.8 11.5 38.7 16.5 4.2 13.4 5.5 34.1 15.6 18.5 3.9 20.7 16.5 88.5 35.2 86.3 0.5 26.4 16.2 28.8 6.1 7.6 123.0 3.6 77.8 0.8 22.9 0.0 0.3 73.1 22.4 6.3 18.1 7.9 8.4 8.0 19.6 4.7 17.7 8.9 6.2 0.0 0.3 15.1 58.4 2.6 2.8 49.8 48.6 15.5 120.3 1.2 13.1 1.3 29.4 0.9 10.8 8.6 8.2 4.0 6.5 5.9 30.8 77.0 LY86 "dJ80N2.1, MD-1" ENSG00000112799 "Lymphocyte antigen 86" O95711 6 6588108-6654983 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 78.4" "Group enriched" "Detected in many" 9 "B-cells: 124.9;Hofbauer cells: 191.7;Kupffer cells: 199.1;Langerhans cells: 118.6;Macrophages: 149.8;Microglial cells: 105.9;monocytes: 155.6" "Cancer enhanced" "Detected in all" "glioma: 22.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 426.6;myeloid DC: 426.1" "Group enriched" "Detected in all" 43 "B-cells: 335.1;dendritic cells: 426.1;monocytes: 426.6" "Cell line enhanced" "Detected in some" "Daudi: 69.5;NB-4: 44.7;RPMI-8226: 245.0;THP-1: 103.8;U-937: 45.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025000, HPA044895" Approved "Secreted to blood" NA NA 77000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" "CAB025000: , HPA044895: AB_2679138" "unprognostic (1.82e-1)" "unprognostic (2.49e-3)" "unprognostic (2.01e-2)" "unprognostic (7.88e-2)" "unprognostic (2.15e-1)" "unprognostic (1.93e-1)" "unprognostic (2.53e-1)" "unprognostic (1.46e-3)" "unprognostic (3.52e-2)" "unprognostic (3.17e-1)" "unprognostic (1.69e-1)" "unprognostic (1.16e-1)" "unprognostic (5.82e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (5.61e-4)" "unprognostic (1.11e-1)" "unprognostic (4.20e-2)" 9.7 10.3 14.0 30.9 13.5 29.2 7.4 14.7 22.0 8.2 14.2 7.6 4.9 3.8 2.8 3.1 4.3 14.6 2.9 13.5 15.8 3.1 13.3 29.7 72.1 17.8 15.4 3.3 3.0 3.4 2.3 14.5 18.7 3.8 11.1 1.2 5.5 6.2 0.7 3.4 16.8 11.1 17.8 52.7 6.2 1.8 18.0 15.1 1.5 1.1 78.4 15.6 1.1 24.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 44.7 0.0 0.0 0.0 8.0 0.0 245.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 103.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 30.3 0.0 45.8 0.0 4.1 426.6 3.5 1.0 234.9 0.7 335.1 1.1 1.1 426.1 248.8 4.7 2.7 9.1 5.3 88.3 16.3 1.8 221.1 14.0 13.5 14.7 22.0 13.5 15.8 17.8 15.4 18.7 17.8 18.0 24.8 1.2 0.0 15.0 1.6 124.9 2.0 0.0 0.0 0.0 0.0 0.9 3.7 1.5 1.5 1.3 0.0 0.0 1.4 9.8 0.0 0.0 0.0 3.4 0.4 0.1 5.4 0.0 3.8 3.8 0.0 1.8 2.1 0.0 0.0 1.3 0.0 4.2 1.3 191.7 0.0 0.6 0.3 0.0 199.1 118.6 15.4 0.3 149.8 0.0 105.9 155.6 0.0 4.1 0.5 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.7 0.4 6.6 0.4 0.2 5.3 0.2 0.3 2.4 1.9 3.6 0.0 0.2 0.2 LY9 "CD229, hly9, mLY9, SLAMF3" ENSG00000122224 "Lymphocyte antigen 9" Q9HBG7 1 160796074-160828261 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.5;intestine: 12.0;lymphoid tissue: 31.1" "Cell type enhanced" "Detected in some" "B-cells: 244.0;dendritic cells: 36.2;Melanocytes: 71.2;Plasma cells: 102.5;T-cells: 44.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 112.9;MAIT T-cell: 113.5;memory B-cell: 56.1;memory CD4 T-cell: 97.6;memory CD8 T-cell: 109.8;naive B-cell: 52.8;naive CD4 T-cell: 109.6;naive CD8 T-cell: 112.3;plasmacytoid DC: 72.8;T-reg: 80.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 14.3;JURKAT: 14.1;Karpas-707: 28.0;U-266/70: 70.7;U-266/84: 29.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA050917 Approved Approved "Plasma membrane,Centriolar satellite" NA NA 43000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Centriolar satellite" "HPA050917: AB_2681272" "unprognostic (8.04e-4)" "unprognostic (2.31e-5)" "unprognostic (8.08e-3)" "unprognostic (1.20e-3)" "unprognostic (9.83e-3)" "unprognostic (1.87e-5)" "unprognostic (1.16e-2)" "unprognostic (3.84e-3)" "unprognostic (1.23e-2)" "unprognostic (2.89e-3)" "unprognostic (1.64e-1)" "unprognostic (2.30e-1)" "unprognostic (2.70e-3)" "unprognostic (8.69e-2)" "unprognostic (9.47e-2)" "unprognostic (3.49e-2)" "unprognostic (6.88e-2)" 2.4 0.9 0.1 13.7 0.2 11.5 2.0 0.1 0.2 0.8 0.2 3.9 4.0 0.6 0.4 0.9 0.9 2.5 0.5 0.1 0.2 1.1 2.3 3.8 30.2 0.3 0.2 0.6 0.2 0.0 0.2 0.3 0.2 1.1 3.8 0.0 7.1 0.4 0.3 0.8 12.0 0.5 0.3 26.7 6.0 0.2 0.2 25.5 1.4 0.2 31.1 3.5 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 28.0 0.0 0.0 2.3 0.5 0.1 0.8 0.0 1.6 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 70.7 29.3 0.3 0.0 4.0 0.0 1.2 0.8 0.4 112.9 1.1 113.5 56.1 97.6 109.8 5.2 52.8 109.6 112.3 2.4 22.2 0.8 72.8 80.3 53.5 0.1 0.2 0.1 0.2 0.1 0.2 0.3 0.2 0.2 0.3 0.2 0.2 0.4 0.0 1.8 0.3 244.0 1.0 0.5 0.1 0.0 0.0 0.4 0.8 0.9 0.0 0.0 0.0 0.0 0.1 36.2 0.1 0.0 0.0 0.1 0.1 0.1 0.7 1.2 28.0 0.1 0.2 0.0 1.4 0.5 0.1 0.0 0.0 1.8 0.4 1.9 0.0 0.1 0.0 0.0 3.2 31.9 0.0 0.0 6.3 71.2 1.9 2.1 0.0 22.6 0.0 0.1 0.1 0.0 0.0 102.5 0.2 0.0 0.3 0.0 0.0 0.0 0.5 0.6 0.0 0.1 0.5 1.0 0.1 44.8 0.0 0.3 0.3 LYPD5 FLJ30469 ENSG00000159871 "LY6/PLAUR domain containing 5" Q6UWN5 19 43785874-43827206 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 50.6" "Cell type enhanced" "Detected in many" "Early spermatids: 33.0;Late spermatids: 81.8;Melanocytes: 17.8;Syncytiotrophoblasts: 21.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 3.5;BEWO: 5.0;HaCaT: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042511, HPA054670" Approved Approved Nucleoplasm,Cytosol No NA "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA042511: AB_10794279, HPA054670: AB_2682567" "unprognostic (4.27e-3)" "prognostic favorable (5.84e-4)" "unprognostic (4.63e-2)" "unprognostic (8.42e-3)" "unprognostic (4.80e-2)" "unprognostic (2.91e-3)" "unprognostic (3.96e-1)" "unprognostic (7.93e-3)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" "unprognostic (1.40e-3)" "unprognostic (1.19e-1)" "unprognostic (1.83e-3)" "unprognostic (8.30e-2)" "unprognostic (2.02e-1)" "unprognostic (7.53e-3)" "unprognostic (4.08e-2)" 1.1 0.6 2.6 1.4 2.5 0.1 2.9 1.8 6.0 9.3 0.0 2.3 0.1 0.9 1.4 11.4 0.8 1.1 1.5 3.0 2.9 3.0 0.4 4.0 0.7 6.8 3.2 0.4 0.3 0.6 1.6 1.0 6.6 1.3 0.8 2.0 3.1 0.8 0.2 50.6 1.2 1.1 1.7 4.8 1.0 3.8 4.1 0.9 1.4 0.4 1.7 1.9 9.0 4.1 3.5 0.0 0.2 0.0 0.0 0.0 5.0 0.0 0.0 0.5 0.6 0.4 1.2 0.2 0.7 0.4 1.4 5.2 0.0 0.7 0.3 0.6 0.0 0.1 0.4 0.0 1.5 0.1 0.0 1.7 1.5 0.2 0.7 0.0 0.2 0.1 0.1 0.1 0.0 0.2 0.1 0.0 0.3 1.9 1.2 0.0 0.0 0.0 0.3 0.6 0.2 0.1 0.7 0.7 0.0 1.1 0.4 0.1 0.3 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.3 0.0 0.0 0.1 2.6 2.5 1.8 6.0 3.0 2.9 6.8 3.2 6.6 1.7 4.1 4.1 0.5 0.0 0.0 4.6 0.0 3.6 2.6 1.6 4.0 1.4 1.8 1.5 0.7 0.0 0.4 0.0 0.0 1.6 0.1 3.7 3.9 0.6 33.0 0.2 0.1 3.1 0.0 0.0 7.7 0.9 8.4 1.2 0.0 0.2 0.0 0.5 0.7 0.0 2.4 0.0 8.8 1.9 0.0 0.6 0.8 81.8 0.3 0.5 17.8 1.0 0.0 0.9 0.0 9.5 7.8 0.3 2.3 1.2 0.0 1.4 0.2 0.0 1.4 0.9 0.0 1.0 0.2 9.9 2.6 3.7 2.8 21.6 0.1 0.1 0.8 6.2 LYPLAL1 Q96AV0 ENSG00000143353 "Lysophospholipase like 1" Q5VWZ2 1 219173869-219212865 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 209.4;Proximal tubular cells: 349.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045806 Approved Supported Cytosol NA NA 8600 "Cluster 30: Non-specific - Translation" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA045806: AB_10966647" "unprognostic (1.27e-2)" "unprognostic (1.29e-1)" "unprognostic (3.98e-2)" "unprognostic (8.64e-2)" "unprognostic (2.41e-1)" "unprognostic (1.49e-1)" "unprognostic (2.01e-1)" "unprognostic (3.73e-2)" "unprognostic (4.08e-2)" "unprognostic (2.05e-1)" "unprognostic (1.16e-1)" "unprognostic (2.76e-2)" "prognostic favorable (1.31e-4)" "unprognostic (1.68e-1)" "unprognostic (5.87e-2)" "unprognostic (1.73e-1)" "unprognostic (4.65e-2)" 9.3 17.9 7.5 3.8 7.6 1.1 10.0 7.8 11.3 8.5 7.2 5.6 8.6 7.3 3.6 7.9 5.4 8.6 36.5 7.3 8.5 42.3 27.3 7.0 8.6 7.9 7.5 9.8 7.6 11.8 5.8 8.2 7.9 13.2 5.9 6.5 8.5 6.5 7.4 9.6 7.5 7.8 8.0 4.4 6.1 6.5 7.4 5.8 16.2 12.1 7.7 6.0 3.9 8.8 9.1 9.4 4.1 0.0 8.1 16.3 10.3 5.3 5.9 4.8 5.6 4.3 12.9 10.0 13.9 4.5 4.7 4.9 8.6 12.1 7.3 13.7 9.3 5.8 4.9 9.8 32.9 12.6 4.3 19.5 11.1 4.8 12.1 11.3 14.5 9.5 16.8 10.2 11.4 6.1 6.1 10.3 7.8 8.6 15.4 3.3 10.5 17.5 19.9 7.1 10.1 5.6 6.3 16.9 17.7 13.5 16.2 15.6 7.8 4.0 2.0 8.2 6.2 8.7 5.3 6.8 13.5 10.1 9.0 0.9 2.0 1.5 0.8 1.8 1.9 3.3 1.3 1.0 1.8 2.0 2.3 1.8 2.2 1.4 1.8 1.5 1.6 1.3 7.5 7.6 7.8 11.3 7.3 8.5 7.9 7.5 7.9 8.0 7.4 8.8 23.6 25.6 35.5 93.0 37.1 22.2 18.7 75.5 29.0 28.5 23.9 25.4 105.9 31.5 42.0 51.5 8.4 89.5 12.8 10.8 209.4 49.3 40.9 7.7 17.4 16.3 18.6 10.3 50.2 53.2 35.4 29.7 11.7 23.6 17.1 18.5 22.9 39.8 64.8 18.5 51.7 18.0 44.7 26.8 21.2 7.8 27.1 49.3 42.7 79.6 27.1 108.7 20.6 82.9 123.4 37.5 16.9 30.9 15.0 13.0 33.4 349.2 38.2 28.9 13.1 24.8 23.3 36.0 24.8 24.9 29.3 62.5 14.2 26.5 15.8 12.3 LYRM4 "C6orf149, CGI-203, ISD11" ENSG00000214113 "LYR motif containing 4" Q9HD34 6 5103629-5260950 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA030362 Approved Supported "Nuclear bodies" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" "Nuclear bodies" "HPA030362: AB_10601546" "unprognostic (2.41e-2)" "unprognostic (3.72e-2)" "unprognostic (7.68e-2)" "unprognostic (8.58e-2)" "unprognostic (1.30e-1)" "unprognostic (8.73e-2)" "unprognostic (1.85e-3)" "unprognostic (4.58e-2)" "unprognostic (7.83e-2)" "unprognostic (2.11e-1)" "unprognostic (1.03e-1)" "unprognostic (2.26e-1)" "unprognostic (2.79e-3)" "unprognostic (1.43e-1)" "unprognostic (2.76e-1)" "unprognostic (9.80e-2)" "unprognostic (5.23e-1)" 16.9 18.8 22.8 14.6 22.5 19.0 19.0 21.4 31.0 16.2 24.0 14.7 7.7 18.1 18.1 13.4 19.1 11.2 20.5 22.3 22.1 14.5 13.6 12.1 22.9 22.7 21.7 27.1 19.4 15.9 20.4 14.2 22.3 12.3 16.2 15.9 13.0 10.2 14.4 17.1 10.4 16.6 22.3 15.9 14.1 16.0 21.8 20.8 19.5 11.0 21.8 16.9 14.2 24.1 28.9 27.4 41.1 32.0 41.3 60.1 37.1 27.1 44.0 36.9 38.0 57.8 19.2 44.7 51.7 35.8 51.6 25.4 58.9 34.2 41.0 79.4 45.9 19.7 20.9 77.4 25.9 52.2 19.2 47.9 53.1 33.1 43.3 34.9 35.8 42.4 64.3 15.2 32.1 15.6 49.6 70.5 39.6 45.9 42.1 49.2 30.8 82.2 38.6 23.4 55.2 35.6 23.8 14.6 65.5 58.6 39.8 44.7 29.5 39.2 26.3 32.9 44.8 22.4 82.4 42.7 19.0 36.6 54.2 1.9 18.8 2.1 11.7 19.8 15.6 31.3 17.5 13.3 34.4 26.2 26.6 24.6 4.3 23.6 17.5 23.0 19.1 17.6 22.8 22.5 21.4 31.0 22.3 22.1 22.7 21.7 22.3 22.3 21.8 24.1 75.6 25.6 16.2 28.4 45.0 73.5 55.6 80.9 25.0 16.4 51.9 48.4 29.1 28.6 33.9 18.4 8.4 49.5 23.0 12.3 31.3 44.1 38.8 26.0 29.3 40.3 32.3 32.0 103.4 43.8 72.2 37.6 11.2 19.0 41.3 39.6 41.7 35.9 65.2 11.8 57.4 26.5 32.6 46.8 93.0 91.7 46.3 31.7 69.4 32.8 74.2 45.1 23.7 80.4 50.8 34.1 15.3 35.3 32.6 108.9 7.2 90.0 26.6 16.8 32.9 32.2 34.8 79.4 78.7 32.1 82.8 47.2 29.5 43.9 38.6 63.5 MAF1 DKFZp586G1123 ENSG00000179632 "MAF1 homolog, negative regulator of RNA polymerase III" Q9H063 8 144104461-144107611 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024821, HPA058548" Uncertain Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Nucleoli, Vesicles" "HPA024821: AB_2671696, HPA058548: AB_2683751" "unprognostic (2.26e-1)" "unprognostic (3.05e-1)" "unprognostic (2.71e-2)" "unprognostic (2.21e-1)" "unprognostic (8.51e-2)" "unprognostic (9.67e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (6.12e-2)" "unprognostic (4.92e-2)" "unprognostic (5.90e-3)" "unprognostic (9.42e-2)" "unprognostic (6.48e-2)" "unprognostic (9.40e-3)" "unprognostic (9.02e-2)" "unprognostic (2.59e-1)" "unprognostic (2.38e-1)" "unprognostic (3.99e-2)" 96.2 84.4 86.6 61.7 89.7 164.4 92.4 87.3 98.3 97.1 82.5 186.9 62.1 101.9 63.6 81.8 93.3 63.0 193.4 83.5 82.7 89.8 61.1 78.0 78.6 91.2 87.6 110.3 84.6 87.4 71.0 65.1 86.4 103.6 58.3 35.4 77.5 94.6 413.1 69.6 92.2 80.5 85.3 96.5 102.1 76.4 88.7 90.8 78.6 294.7 69.5 130.7 84.1 90.5 119.8 187.1 85.4 86.3 229.0 113.3 68.9 91.8 151.0 140.5 142.1 69.2 129.1 131.0 150.4 154.9 78.1 71.4 117.4 129.9 103.0 115.4 139.5 144.5 127.8 109.6 154.1 62.0 94.4 100.7 150.0 112.8 211.4 156.7 153.6 94.1 112.5 86.9 85.0 281.2 230.9 112.3 64.0 216.3 490.2 90.3 119.7 141.8 89.0 88.8 123.8 102.2 122.0 156.7 152.6 79.5 106.7 93.9 93.0 65.0 146.0 116.1 117.5 102.7 86.0 62.2 107.8 113.7 44.0 50.4 98.0 126.5 72.8 76.1 81.0 110.2 105.0 117.5 107.6 129.9 110.9 105.0 52.9 93.1 78.4 81.0 84.1 111.9 86.6 89.7 87.3 98.3 83.5 82.7 91.2 87.6 86.4 85.3 88.7 90.5 76.8 16.0 15.6 6.8 95.2 92.9 92.4 51.6 53.5 41.4 76.5 77.8 54.2 42.9 24.8 44.1 14.6 106.4 113.9 82.6 105.7 101.1 86.1 30.0 39.3 69.7 93.3 129.0 5.0 107.9 103.6 66.3 28.5 43.6 32.5 77.3 67.5 29.3 97.6 37.0 5.5 89.7 32.6 72.3 85.6 41.0 88.3 84.9 78.2 6.5 138.0 82.0 138.0 7.1 10.7 106.0 97.4 93.3 60.3 170.3 155.0 110.2 12.9 37.6 98.6 65.5 84.8 96.1 43.3 54.0 89.8 144.3 87.6 72.4 88.5 122.4 MAGI3 MAGI-3 ENSG00000081026 "Membrane associated guanylate kinase, WW and PDZ domain containing 3" Q5TCQ9 1 113390515-113685923 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 34.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 266.0;Excitatory neurons: 206.7;Oligodendrocyte precursor cells: 128.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008444 Supported "Cell Junctions" NA NA "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions" "HPA008444: AB_2668069" "unprognostic (4.07e-1)" "unprognostic (3.59e-2)" "unprognostic (1.54e-3)" "unprognostic (2.32e-2)" "unprognostic (2.31e-2)" "unprognostic (5.21e-3)" "unprognostic (2.23e-1)" "unprognostic (7.06e-2)" "unprognostic (2.80e-2)" "prognostic favorable (4.29e-4)" "unprognostic (1.09e-2)" "unprognostic (1.03e-1)" "prognostic favorable (2.60e-8)" "unprognostic (1.71e-2)" "unprognostic (7.85e-2)" "unprognostic (2.65e-1)" "unprognostic (1.50e-2)" 2.8 3.3 5.4 2.3 7.1 0.2 7.6 2.8 8.6 3.5 2.8 9.2 5.9 4.9 6.5 7.6 3.7 3.8 3.2 5.4 5.4 7.1 6.2 13.2 1.2 4.0 7.4 6.0 10.7 3.9 4.7 7.4 6.6 4.2 8.2 34.8 4.3 2.6 1.5 1.9 7.5 4.6 2.0 2.3 11.6 4.1 5.2 2.4 10.9 2.4 3.8 2.7 4.0 5.9 8.8 10.8 10.0 4.5 4.4 6.4 2.7 6.1 3.0 4.8 5.3 9.5 2.6 0.4 4.5 5.7 4.1 3.9 9.1 4.7 5.9 9.5 8.6 4.0 9.6 4.3 1.0 3.3 5.6 3.4 2.3 5.1 11.0 5.7 6.7 4.2 4.7 8.4 6.6 5.9 5.2 0.9 3.5 15.3 6.3 7.3 16.1 1.0 5.5 4.0 8.9 9.0 7.4 12.1 2.2 12.3 6.3 1.7 11.6 7.8 9.8 7.1 8.7 3.1 2.8 0.0 4.1 1.5 6.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 5.4 7.1 2.8 8.6 5.4 5.4 4.0 7.4 6.6 2.0 5.2 5.9 14.0 266.0 103.2 106.7 1.3 10.8 9.1 9.2 21.1 97.1 27.1 16.0 9.2 14.3 60.7 12.9 50.1 16.0 1.0 51.8 7.9 10.9 39.4 11.2 19.7 11.9 13.8 3.2 206.7 10.7 2.4 14.9 37.8 15.9 6.3 12.1 12.1 14.4 4.1 40.4 100.1 23.6 4.1 2.2 6.9 28.4 10.2 2.6 12.4 92.8 0.5 35.6 0.0 128.7 17.7 13.5 40.2 11.3 8.8 9.5 32.6 5.3 17.5 45.6 13.1 13.4 10.7 23.8 9.6 23.4 7.5 5.5 4.1 8.7 28.9 10.5 MAGT1 "DKFZp564K142, IAP, MRX95, OST3B, SLC58A1" ENSG00000102158 "Magnesium transporter 1" Q9H0U3 X 77825747-77895593 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 145.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049851 Approved "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA049851: AB_2680913" "prognostic unfavorable (1.30e-4)" "unprognostic (3.32e-1)" "unprognostic (6.47e-2)" "unprognostic (1.16e-1)" "unprognostic (2.39e-1)" "unprognostic (3.81e-3)" "unprognostic (1.07e-1)" "unprognostic (2.47e-2)" "prognostic unfavorable (8.98e-4)" "unprognostic (2.03e-2)" "prognostic unfavorable (3.55e-4)" "unprognostic (1.03e-1)" "unprognostic (1.60e-2)" "unprognostic (5.56e-3)" "unprognostic (1.14e-1)" "unprognostic (6.25e-3)" "unprognostic (1.66e-1)" 25.3 22.6 12.9 24.2 19.4 20.8 36.5 17.2 17.4 39.4 14.4 28.3 25.7 27.5 53.7 25.6 25.9 25.1 37.5 13.0 16.4 41.9 71.2 26.8 22.5 20.9 18.5 23.6 31.9 38.4 18.5 36.4 21.9 33.5 27.0 5.2 34.6 28.0 17.1 18.3 26.2 24.3 16.6 23.5 29.4 11.3 17.9 21.0 78.0 21.9 23.5 29.1 18.2 27.0 62.5 34.1 41.7 48.8 75.0 49.3 64.8 66.9 67.4 51.7 56.5 45.6 99.5 45.6 90.9 71.7 53.3 56.4 88.4 50.8 80.0 32.3 55.4 30.6 46.2 42.5 66.6 64.9 31.1 45.3 43.5 64.6 56.7 55.1 74.0 31.2 36.5 123.2 64.7 40.4 36.2 23.9 56.1 64.6 41.3 43.3 72.5 84.7 61.9 45.8 14.1 26.3 91.6 64.8 58.0 43.6 43.8 35.3 75.2 45.6 51.1 71.7 33.2 44.8 103.1 58.1 49.7 60.5 61.0 15.3 12.9 13.7 17.2 19.7 18.4 12.5 15.6 16.6 11.1 10.7 14.9 17.7 11.0 18.6 21.0 22.2 12.8 15.7 12.9 19.4 17.2 17.4 13.0 16.4 20.9 18.5 21.9 16.6 17.9 27.0 50.2 41.7 53.6 9.8 37.3 33.0 55.3 51.6 24.5 5.2 39.1 25.1 53.4 42.9 51.6 40.5 4.2 33.3 43.4 44.8 3.9 35.3 2.2 23.7 38.9 40.7 22.7 33.0 6.1 34.9 59.3 43.7 33.1 58.0 30.4 24.5 43.2 145.6 42.3 1.7 6.3 39.6 32.6 49.8 46.1 2.5 30.7 45.1 33.8 15.9 33.9 17.1 18.6 13.6 28.0 36.2 37.2 27.1 87.4 65.4 31.2 32.0 20.7 5.2 19.7 38.7 31.2 6.6 16.7 36.5 45.6 81.3 36.0 31.2 26.0 69.4 MAIP1 "C2orf47, DKFZp666A212, FLJ22555" ENSG00000162972 "Matrix AAA peptidase interacting protein 1" Q8WWC4 2 199955317-200008540 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 30.0;Distal tubular cells: 37.2;Ductal cells: 31.4;Exocrine glandular cells: 28.0;Extravillous trophoblasts: 33.8;Proximal tubular cells: 84.2;Syncytiotrophoblasts: 32.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064013, HPA072231" Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA064013: AB_2685175, HPA072231: AB_2732196" "unprognostic (4.89e-2)" "unprognostic (7.36e-2)" "unprognostic (7.40e-3)" "prognostic unfavorable (2.14e-4)" "unprognostic (2.74e-1)" "prognostic unfavorable (3.81e-4)" "unprognostic (4.86e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.87e-4)" "unprognostic (1.02e-3)" "unprognostic (7.03e-2)" "unprognostic (2.00e-2)" "unprognostic (5.21e-3)" "unprognostic (1.45e-1)" "unprognostic (1.94e-1)" "unprognostic (1.63e-1)" "unprognostic (2.70e-2)" 11.1 16.1 7.0 8.3 7.2 18.7 11.3 10.1 8.4 7.3 6.5 14.4 21.1 7.8 7.4 11.7 9.0 8.1 16.6 7.5 6.5 31.1 46.2 7.4 8.8 6.7 6.5 7.5 10.3 12.2 5.8 9.3 7.3 9.1 13.1 7.2 9.6 9.0 22.2 9.7 16.8 7.5 7.1 8.5 12.6 4.9 6.8 9.3 9.7 16.8 10.4 9.2 8.2 8.6 23.9 21.8 19.3 15.2 16.8 16.9 44.5 21.1 20.2 30.7 29.3 59.5 21.0 15.7 29.6 14.6 25.4 25.8 28.7 22.7 28.8 24.7 32.9 26.4 18.5 54.7 22.6 36.7 18.0 18.1 18.3 20.3 21.9 17.6 19.7 29.9 35.2 19.8 20.2 31.4 27.8 34.0 24.7 25.2 51.6 26.4 22.9 31.6 36.6 30.5 21.8 15.1 21.7 24.4 40.1 24.3 21.6 22.1 17.6 17.9 25.6 15.6 23.7 18.8 23.6 33.7 27.0 21.1 18.7 9.9 12.9 9.4 10.8 12.8 13.3 13.8 10.6 7.7 16.8 14.1 10.0 8.6 2.0 8.9 12.6 13.5 13.9 8.2 7.0 7.2 10.1 8.4 7.5 6.5 6.7 6.5 7.3 7.1 6.8 8.6 11.7 9.6 14.9 0.0 2.1 0.0 0.0 0.0 0.0 0.0 10.8 14.1 0.0 0.0 5.0 3.7 0.0 30.0 7.0 0.0 37.2 31.4 0.0 10.0 10.2 6.1 0.0 0.0 0.0 28.0 33.8 6.2 0.0 11.9 3.8 12.2 0.0 0.0 23.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 6.7 0.0 0.0 0.0 0.0 21.2 0.0 0.0 1.3 0.0 0.0 84.2 5.8 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 32.0 4.0 18.3 0.0 0.0 MAJIN C11orf85 ENSG00000168070 "Membrane anchored junction protein" Q3KP22 11 64937517-64972108 "Predicted intracellular proteins" Meiosis DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 22.5" "Group enriched" "Detected in some" 8 "Distal tubular cells: 3.9;Proximal tubular cells: 9.5" "Cancer enhanced" "Detected in some" "cervical cancer: 1.0" "Region enriched" "Detected in single" 4 "cerebellum: 2.6" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.3" "Lineage enriched" "Detected in single" 5 "B-cells: 1.3" "Group enriched" "Detected in some" 10 "CAPAN-2: 7.5;SiHa: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (3.37e-1)" "unprognostic (6.43e-3)" "unprognostic (3.69e-2)" "unprognostic (7.05e-2)" "unprognostic (9.64e-3)" "unprognostic (2.92e-2)" "unprognostic (4.46e-2)" "unprognostic (1.06e-1)" "unprognostic (9.11e-2)" "unprognostic (4.11e-2)" "unprognostic (1.61e-2)" "unprognostic (2.58e-1)" "unprognostic (1.48e-2)" "unprognostic (2.43e-1)" "unprognostic (2.79e-1)" "unprognostic (4.18e-3)" "unprognostic (1.76e-2)" 0.0 0.2 0.2 0.2 0.6 0.1 0.2 2.6 0.6 0.1 0.0 0.1 0.0 0.0 2.0 0.1 1.1 2.9 0.0 0.1 0.1 1.4 1.2 0.2 1.4 0.5 0.2 0.0 0.3 0.0 0.0 0.1 0.3 0.3 0.2 0.2 0.1 0.6 0.0 1.2 0.4 0.0 0.2 0.6 0.2 22.5 0.1 0.1 0.9 0.0 1.3 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 2.6 0.6 0.1 0.1 0.5 0.2 0.3 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.3 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 MAN1A2 MAN1B ENSG00000198162 "Mannosidase alpha class 1A member 2" O60476 1 117367449-117528872 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 236.1;Inhibitory neurons: 238.0;Syncytiotrophoblasts: 380.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034559, HPA057364" Enhanced Enhanced "Golgi apparatus" NA NA 2000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA034559: AB_10671229, HPA057364: AB_2683419" "unprognostic (2.24e-1)" "unprognostic (1.20e-1)" "unprognostic (2.92e-3)" "unprognostic (2.15e-1)" "unprognostic (3.11e-2)" "unprognostic (9.70e-2)" "unprognostic (1.95e-2)" "unprognostic (8.01e-2)" "unprognostic (8.19e-3)" "prognostic favorable (4.08e-4)" "unprognostic (1.41e-1)" "unprognostic (4.38e-2)" "unprognostic (6.84e-2)" "unprognostic (1.45e-1)" "unprognostic (7.39e-2)" "unprognostic (1.17e-1)" "unprognostic (5.08e-2)" 15.6 11.7 6.7 13.0 12.0 6.3 12.9 8.8 11.6 17.5 7.7 12.5 11.1 16.4 13.7 15.2 14.2 12.3 11.0 7.2 8.5 15.3 21.1 10.8 14.1 1.6 5.0 14.3 36.2 32.9 6.7 21.7 1.6 14.4 12.5 18.2 14.0 13.1 8.4 10.3 11.6 18.0 1.0 12.2 14.2 10.8 6.2 14.7 25.4 10.1 13.8 17.8 7.7 9.8 32.4 13.8 23.2 20.1 29.8 35.7 74.2 26.3 40.9 11.6 10.9 10.7 18.2 24.2 47.4 33.9 10.8 18.7 11.0 22.3 26.0 30.3 16.4 14.4 18.5 11.8 18.1 22.7 31.6 24.2 23.5 17.8 15.5 21.3 35.0 16.7 23.5 36.1 24.5 62.6 14.0 7.2 11.9 16.4 14.4 12.5 50.5 16.7 15.9 43.3 12.6 18.4 26.2 27.6 21.1 30.1 13.8 14.2 33.6 26.0 21.4 18.6 27.2 24.4 18.0 15.9 34.4 17.8 63.1 0.9 1.5 2.6 3.0 1.2 3.6 1.9 2.4 2.5 1.4 1.9 2.0 2.9 1.2 3.8 1.1 2.7 6.3 1.5 6.7 12.0 8.8 11.6 7.2 8.5 1.6 5.0 1.6 1.0 6.2 9.8 40.3 38.5 33.4 71.5 45.1 31.0 34.8 26.7 39.3 63.5 43.3 46.0 101.8 35.8 39.1 44.1 22.9 55.1 52.6 24.7 17.6 32.3 33.1 43.2 52.0 40.6 21.7 43.8 188.5 60.4 236.1 50.7 28.5 54.7 16.4 32.3 42.1 88.7 29.4 43.7 238.0 37.1 20.3 36.2 22.0 22.5 53.7 37.2 40.9 101.2 39.2 51.3 55.6 136.7 149.1 37.5 25.1 65.5 120.2 43.0 28.6 22.1 40.9 42.2 39.5 69.1 53.5 72.9 56.2 53.0 34.5 380.5 45.8 68.3 30.8 47.3 MAN2A1 "GOLIM7, MANA2" ENSG00000112893 "Mannosidase alpha class 2A member 1" Q16706 5 109689927-109869625 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 107.8" "Cell type enriched" "Detected in many" 9 "Oligodendrocytes: 2117.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022377, HPA026896" Enhanced Supported "Golgi apparatus" NA NA 110000000 "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "CAB022377: , HPA026896: AB_1853512" "unprognostic (1.62e-2)" "unprognostic (4.06e-2)" "unprognostic (1.25e-2)" "unprognostic (6.96e-2)" "unprognostic (2.52e-1)" "unprognostic (1.08e-1)" "unprognostic (5.80e-2)" "unprognostic (4.20e-2)" "unprognostic (3.91e-1)" "unprognostic (2.90e-2)" "unprognostic (4.73e-2)" "unprognostic (1.23e-1)" "unprognostic (6.77e-3)" "unprognostic (2.03e-2)" "unprognostic (1.20e-2)" "unprognostic (1.11e-3)" "unprognostic (5.31e-3)" 11.2 17.0 28.0 13.9 66.1 12.7 11.3 41.4 29.6 13.8 3.8 20.7 30.1 12.0 4.2 8.5 9.0 18.1 3.7 21.7 31.5 17.4 42.4 10.1 15.8 64.5 49.9 9.8 22.2 20.7 0.9 15.3 62.1 9.1 20.8 1.7 6.5 10.2 6.0 7.4 25.7 18.3 39.4 14.1 15.7 9.5 42.8 22.7 14.7 11.5 14.7 16.1 2.7 107.8 23.1 18.6 26.5 11.0 56.2 42.2 97.5 49.3 78.0 26.1 46.7 23.2 37.0 17.4 30.7 63.3 18.5 26.5 14.5 56.0 59.7 16.3 9.7 32.6 13.5 30.7 34.6 15.9 15.5 39.7 25.0 43.4 61.4 37.3 54.5 16.9 8.8 87.0 70.5 13.8 27.6 9.1 20.4 17.9 7.3 10.8 40.0 78.5 34.1 32.8 3.7 3.3 22.6 24.9 16.1 29.1 20.5 17.1 56.4 53.7 21.3 30.1 32.9 48.7 58.7 13.6 41.8 22.4 30.3 4.1 2.0 0.6 1.6 2.8 1.3 1.9 2.8 2.8 1.8 1.6 3.3 2.7 1.6 0.5 4.4 2.0 2.8 1.1 28.0 66.1 41.4 29.6 21.7 31.5 64.5 49.9 62.1 39.4 42.8 107.8 20.9 6.4 8.4 100.9 41.1 17.8 15.8 12.7 29.6 0.6 20.0 9.5 7.6 34.3 14.7 31.3 0.0 19.4 28.9 65.8 1.9 27.1 13.7 10.2 35.8 21.6 24.7 29.2 220.8 35.3 98.0 32.3 45.3 33.3 15.2 19.2 36.8 130.3 18.0 0.0 115.2 35.2 22.4 74.8 24.6 8.3 9.9 47.4 26.6 102.1 39.6 5.9 13.4 46.8 2117.7 28.8 28.4 6.8 84.0 39.8 60.6 24.7 12.1 0.2 19.7 52.6 16.5 16.5 19.9 33.6 23.7 23.7 34.7 14.2 49.6 24.2 MANEA "FLJ12838, mandaselin" ENSG00000172469 "Mannosidase endo-alpha" Q5SRI9 6 95577535-95609452 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 59.8;Plasma cells: 113.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011046, HPA011069" Enhanced Supported "Golgi apparatus" NA NA 140000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA011046: AB_1079303, HPA011069: AB_1079304" "unprognostic (6.00e-2)" "unprognostic (7.81e-2)" "prognostic favorable (3.04e-4)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" "unprognostic (5.03e-2)" "unprognostic (2.98e-3)" "unprognostic (2.74e-1)" "unprognostic (5.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.44e-1)" "unprognostic (9.07e-2)" "unprognostic (2.86e-3)" "unprognostic (5.18e-2)" "unprognostic (3.08e-1)" "unprognostic (9.68e-2)" "unprognostic (7.47e-2)" 11.9 6.9 3.1 7.9 3.6 3.3 8.9 3.7 3.7 8.4 4.2 8.1 8.8 6.8 6.3 8.0 6.4 7.9 5.6 2.5 3.7 12.0 24.0 7.3 9.2 4.3 3.3 9.7 8.4 11.1 2.1 6.3 4.4 7.0 8.7 6.1 5.6 7.9 1.4 6.8 8.8 6.7 3.6 9.6 12.1 6.1 3.7 9.1 11.6 3.4 11.2 9.0 3.5 5.6 6.5 5.3 20.4 16.6 33.1 38.5 7.7 17.7 16.2 10.1 14.8 6.1 16.0 12.3 21.7 11.7 14.9 10.4 14.1 12.0 23.2 20.9 12.6 16.6 4.7 10.2 11.5 22.3 14.4 38.4 13.7 12.0 8.5 14.6 24.3 12.1 26.2 28.1 22.0 4.5 13.1 9.5 3.0 17.1 5.5 15.4 19.9 18.8 15.5 11.2 16.3 8.8 10.0 7.2 6.5 14.3 11.4 20.7 22.0 10.1 7.1 18.4 17.8 20.9 12.9 15.2 18.2 19.1 23.6 8.5 2.3 1.3 3.2 4.1 4.6 4.5 3.9 3.8 2.5 2.3 4.5 3.1 0.5 2.9 3.7 1.0 7.7 2.4 3.1 3.6 3.7 3.7 2.5 3.7 4.3 3.3 4.4 3.6 3.7 5.6 11.6 12.8 8.4 7.8 15.5 7.4 4.4 6.4 8.6 8.1 8.4 7.4 4.5 10.0 7.4 12.9 4.2 5.4 5.4 1.8 5.9 4.1 16.7 7.3 14.4 10.7 1.8 8.2 6.0 7.3 5.6 12.0 8.2 8.1 2.5 17.8 28.2 59.8 11.0 11.8 7.3 4.6 0.0 12.0 5.8 11.7 5.9 7.9 8.8 8.4 6.8 10.5 3.1 16.1 18.7 3.4 2.8 15.8 113.4 3.4 4.8 8.5 8.5 5.3 13.1 9.8 17.1 7.1 12.1 11.8 7.0 1.4 9.2 13.5 5.0 3.5 MAP3K6 "ASK2, MAPKKK6, MEKK6" ENSG00000142733 "Mitogen-activated protein kinase kinase kinase 6" O95382 1 27354067-27366961 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 45.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA051192 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Plasma membrane, Actin filaments, Cytosol" "HPA051192: AB_2681380" "unprognostic (1.19e-2)" "unprognostic (2.77e-3)" "unprognostic (2.62e-2)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.13e-4)" "prognostic favorable (7.26e-4)" "prognostic unfavorable (8.76e-4)" "unprognostic (9.10e-2)" "unprognostic (2.79e-1)" "unprognostic (6.91e-2)" "unprognostic (6.56e-2)" "unprognostic (1.25e-1)" "unprognostic (4.65e-3)" "unprognostic (4.95e-2)" "unprognostic (2.79e-1)" "unprognostic (7.07e-3)" "unprognostic (1.50e-1)" 42.9 17.8 17.2 5.5 17.0 0.6 42.6 17.4 20.7 50.2 16.8 25.4 1.8 30.9 4.1 70.0 38.8 4.7 61.8 16.6 17.4 37.3 10.4 54.2 4.7 18.4 17.5 15.6 15.2 5.2 18.0 5.1 17.6 41.3 4.5 1.4 30.3 7.3 15.2 65.7 17.7 12.1 17.3 22.3 23.6 8.3 18.4 2.8 30.3 11.3 7.9 39.8 53.4 16.6 7.2 7.2 6.9 4.4 9.9 12.5 1.4 9.0 5.3 7.2 4.4 2.0 9.4 0.1 8.4 16.4 3.2 10.1 2.0 6.4 3.6 6.5 7.1 0.3 16.0 4.7 2.7 0.5 0.4 10.2 17.6 7.8 2.3 8.8 4.0 0.7 2.0 2.7 10.2 25.1 0.2 9.0 2.2 8.7 8.1 2.3 3.2 1.7 12.9 9.1 2.0 3.0 8.5 7.1 6.3 3.1 4.4 5.0 11.6 13.2 7.2 16.6 5.2 3.5 4.1 0.0 12.1 5.8 4.3 0.9 0.6 3.3 2.8 2.0 3.7 1.5 2.5 3.1 1.3 2.0 1.8 1.6 1.2 0.7 4.5 0.0 3.0 1.2 17.2 17.0 17.4 20.7 16.6 17.4 18.4 17.5 17.6 17.3 18.4 16.6 45.8 19.2 17.8 6.2 3.9 12.5 11.9 8.8 17.1 1.1 8.1 8.9 12.2 5.7 10.3 3.7 0.0 1.2 4.3 8.4 3.9 2.8 0.4 2.3 6.0 27.7 0.0 0.8 1.5 4.4 2.5 10.3 8.6 5.2 2.5 1.2 28.9 0.9 2.8 5.0 1.7 6.1 4.1 8.5 7.1 1.2 16.1 6.4 5.4 5.6 9.3 5.4 8.2 0.0 0.2 12.8 1.9 15.1 3.1 9.5 1.1 1.7 6.2 0.8 6.6 10.8 11.1 13.5 7.7 14.7 14.8 0.1 8.2 0.3 8.8 14.9 MAP3K8 "c-COT, COT, EST, ESTF, MEKK8, Tpl-2" ENSG00000107968 "Mitogen-activated protein kinase kinase kinase 8" P41279 10 30434021-30461833 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 332.1" "Cell type enhanced" "Detected in many" "Macrophages: 225.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 44.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB005120, HPA017962" Supported Supported Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 41: Macrophages - Immune response" Cytosol "CAB005120: AB_2140669, HPA017962: AB_1853776" "unprognostic (1.91e-2)" "unprognostic (2.94e-1)" "unprognostic (3.07e-1)" "unprognostic (9.29e-2)" "unprognostic (6.73e-2)" "unprognostic (1.00e-2)" "unprognostic (1.44e-1)" "unprognostic (3.36e-2)" "unprognostic (1.41e-2)" "unprognostic (8.04e-3)" "unprognostic (8.23e-2)" "unprognostic (2.96e-1)" "prognostic unfavorable (8.76e-7)" "unprognostic (1.88e-1)" "unprognostic (1.49e-1)" "unprognostic (1.63e-2)" "unprognostic (5.98e-3)" 69.1 18.8 7.2 39.9 5.8 332.1 31.8 5.9 8.0 15.1 22.1 19.6 8.3 18.3 5.9 23.2 38.0 37.4 18.5 6.7 13.5 12.7 16.2 64.5 33.7 10.7 8.1 12.0 7.4 6.9 8.4 46.5 8.8 11.1 16.4 10.9 12.5 11.2 6.6 36.0 21.1 35.6 9.3 41.7 20.3 3.0 15.9 9.3 14.7 6.1 28.8 49.4 20.4 7.9 15.5 13.7 3.6 7.7 18.3 15.4 17.3 3.8 20.3 8.2 9.6 9.4 34.2 10.3 9.2 8.1 8.1 28.2 8.4 3.7 3.0 23.3 4.4 19.2 25.6 30.8 16.0 6.0 44.2 19.5 2.1 7.4 1.6 7.7 3.6 0.2 8.8 14.7 1.4 8.8 0.2 22.3 1.4 8.3 4.9 1.3 3.0 5.8 7.9 30.8 0.3 1.6 13.7 11.3 1.9 10.0 3.7 12.7 0.1 4.8 4.3 18.0 0.6 22.4 22.7 3.2 6.9 25.3 0.2 45.8 14.7 53.1 15.7 26.4 8.7 20.8 3.3 10.3 14.5 38.0 0.2 6.0 35.5 28.3 38.7 30.0 1.0 10.3 7.2 5.8 5.9 8.0 6.7 13.5 10.7 8.1 8.8 9.3 15.9 7.9 51.0 38.5 49.6 11.8 147.3 116.9 50.0 91.1 109.8 19.0 51.7 24.3 10.1 11.5 67.5 3.7 0.0 29.3 203.6 13.6 1.9 31.4 0.5 149.3 51.4 55.7 12.0 21.2 7.7 11.3 86.8 66.2 33.1 205.6 71.1 1.1 25.0 3.1 128.2 0.0 7.1 6.3 83.4 113.8 205.5 1.1 8.4 225.1 42.7 30.9 64.7 6.1 36.0 2.0 0.7 23.4 20.7 4.1 107.8 46.8 3.9 3.5 78.8 1.6 6.6 23.6 62.3 0.3 0.8 129.1 84.8 159.4 97.8 1.5 6.5 195.6 MAP6 "FLJ41346, KIAA1878, MAP6-N, STOP" ENSG00000171533 "Microtubule associated protein 6" Q96JE9 11 75586918-75669038 "Predicted intracellular proteins" Transport Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 76.8;retina: 96.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 81.2;Cone photoreceptor cells: 158.4;Excitatory neurons: 75.8;Horizontal cells: 50.5;Inhibitory neurons: 43.3;Late spermatids: 41.9" "Cancer enhanced" "Detected in many" "glioma: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AF22: 37.8;CACO-2: 38.1;HDLM-2: 21.5;SCLC-21H: 62.4;SH-SY5Y: 31.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015442, CAB022600, HPA039061, HPA039062" Enhanced Uncertain "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "CAB015442: AB_2140997, CAB022600: , HPA039061: AB_2676325, HPA039062: AB_2676326" "unprognostic (3.04e-2)" "unprognostic (6.18e-2)" "unprognostic (3.15e-2)" "unprognostic (9.07e-2)" "unprognostic (7.54e-2)" "unprognostic (4.49e-2)" "unprognostic (8.29e-2)" "unprognostic (2.51e-2)" "unprognostic (5.99e-2)" "unprognostic (7.99e-2)" "prognostic favorable (3.41e-4)" "prognostic favorable (9.15e-4)" "unprognostic (2.43e-2)" "unprognostic (3.96e-3)" "unprognostic (8.09e-3)" "unprognostic (1.77e-1)" "unprognostic (2.03e-1)" 4.8 19.0 68.3 2.0 68.0 0.0 3.5 50.7 70.6 10.6 64.4 23.0 1.7 18.1 21.0 4.2 40.7 6.4 8.6 67.7 71.5 17.0 1.2 7.8 0.7 70.2 64.6 8.0 3.6 22.0 76.8 1.5 70.8 17.8 3.5 96.1 3.6 21.1 1.0 8.1 4.8 13.1 52.9 2.4 10.7 18.6 68.5 0.8 7.9 1.3 0.5 7.1 8.4 59.7 0.2 0.7 37.8 0.1 0.1 0.0 0.0 3.8 0.2 0.3 0.0 38.1 0.1 0.6 1.4 6.3 1.3 0.0 3.4 0.5 0.0 21.5 0.5 0.0 0.0 0.0 1.0 0.0 0.0 2.1 0.5 0.1 0.2 5.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 5.9 0.0 2.9 0.0 0.0 0.1 0.1 0.5 62.4 31.7 4.6 0.0 0.0 0.8 0.0 0.0 0.9 0.0 0.1 0.1 0.5 0.0 0.0 0.0 6.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.3 68.0 50.7 70.6 67.7 71.5 70.2 64.6 70.8 52.9 68.5 59.7 1.2 3.2 3.7 25.8 0.1 0.8 1.7 0.7 0.0 81.2 0.8 1.8 8.4 1.5 3.1 11.0 158.4 0.2 0.2 0.0 1.9 0.1 27.7 28.2 4.6 1.6 13.1 0.0 75.8 0.2 0.0 2.9 0.0 0.8 0.0 0.8 2.2 0.3 0.1 50.5 43.3 0.0 6.1 0.0 1.1 41.9 7.5 0.3 5.4 1.9 0.0 18.7 0.0 13.0 13.3 0.2 0.0 18.4 0.1 1.4 0.0 1.2 25.4 10.2 0.0 1.9 5.7 23.5 4.3 0.1 0.4 0.0 0.3 0.1 0.0 0.4 MAP7 E-MAP-115 ENSG00000135525 "Microtubule associated protein 7" Q14244 6 136342281-136550819 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 130.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1501.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 12.2" "Group enriched" "Detected in many" 4 "dendritic cells: 5.7;granulocytes: 12.2;monocytes: 3.1" "Cell line enhanced" "Detected in many" "CACO-2: 59.8;HeLa: 69.2;MCF7: 88.5;OE19: 55.3;RT4: 68.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029712, HPA029713" Enhanced Supported Microtubules,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 45: Intestine - Brush border" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol Microtubules "HPA029712: AB_10600303, HPA029713: AB_10601339" "unprognostic (8.68e-3)" "prognostic unfavorable (9.70e-5)" "unprognostic (2.33e-3)" "unprognostic (4.35e-3)" "unprognostic (6.95e-2)" "unprognostic (3.35e-1)" "prognostic favorable (9.22e-4)" "unprognostic (1.24e-1)" "unprognostic (1.71e-1)" "unprognostic (1.72e-1)" "unprognostic (4.61e-2)" "unprognostic (3.33e-1)" "prognostic favorable (5.07e-7)" "unprognostic (1.62e-3)" "unprognostic (7.84e-2)" "unprognostic (3.62e-1)" "unprognostic (6.51e-2)" 2.7 8.4 36.6 4.9 81.2 4.8 13.1 53.0 49.8 6.1 0.6 24.6 29.0 2.4 19.5 15.8 10.0 8.2 1.4 40.2 59.8 32.6 17.2 7.0 1.5 78.0 67.2 1.5 25.1 24.9 12.0 6.8 75.8 20.0 23.2 57.3 20.3 6.4 0.8 17.1 26.6 2.4 43.3 1.8 18.7 27.4 63.0 5.1 16.1 0.2 5.1 12.0 9.6 130.4 25.6 39.2 0.3 0.1 0.2 0.2 40.4 0.7 1.2 0.4 0.7 59.8 26.3 0.1 5.3 0.8 6.7 38.2 11.1 34.6 0.7 0.2 24.6 26.6 69.2 0.5 0.3 26.1 3.0 0.1 31.5 0.2 2.4 1.0 0.2 2.0 18.4 0.6 0.1 88.5 0.2 2.6 5.2 55.3 5.7 0.1 1.0 4.8 23.6 68.4 24.4 5.2 27.4 51.7 0.6 9.1 20.5 2.6 0.5 0.1 1.9 0.4 1.7 4.6 6.4 0.2 0.5 10.1 0.7 2.8 2.3 0.0 0.0 1.6 0.3 1.4 0.5 0.0 5.7 1.6 0.1 0.0 12.2 0.7 3.1 0.0 0.2 0.7 36.6 81.2 53.0 49.8 40.2 59.8 78.0 67.2 75.8 43.3 63.0 130.4 4.0 57.7 51.4 117.2 1.9 28.2 48.7 21.7 33.6 367.0 29.5 18.4 3.0 28.6 42.9 18.4 146.0 33.1 0.7 67.9 31.3 35.8 293.9 30.4 5.9 4.9 117.7 35.1 217.1 49.0 23.1 4.4 42.8 60.8 0.0 1.2 0.7 37.0 16.3 304.5 258.6 81.5 22.4 3.2 8.5 53.1 6.8 6.2 17.8 15.0 3.2 50.9 0.0 26.2 1501.2 37.2 51.9 3.4 4.4 56.6 60.7 81.8 56.0 104.7 19.7 2.0 5.2 37.5 23.4 49.0 30.4 76.2 3.4 2.8 64.2 62.8 MAPK11 "p38-2, p38Beta, PRKM11, SAPK2" ENSG00000185386 "Mitogen-activated protein kinase 11" Q15759 22 50263713-50270767 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 70.9" "Cell type enhanced" "Detected in many" "Adipocytes: 29.5;Astrocytes: 16.6;Endothelial cells: 21.1;Excitatory neurons: 15.8;Hepatic stellate cells: 20.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012961, HPA045069" Approved Approved Mitochondria NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Mitochondria "CAB012961: AB_2533144, HPA045069: AB_2679207" "unprognostic (1.11e-1)" "unprognostic (1.28e-1)" "unprognostic (1.49e-2)" "unprognostic (1.92e-1)" "unprognostic (1.18e-2)" "unprognostic (1.64e-3)" "unprognostic (1.02e-1)" "unprognostic (5.84e-2)" "unprognostic (5.89e-2)" "unprognostic (2.46e-1)" "unprognostic (4.96e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (6.02e-6)" "unprognostic (9.84e-2)" "unprognostic (4.25e-2)" "unprognostic (9.16e-2)" "unprognostic (2.10e-2)" 27.5 6.8 52.3 7.9 56.0 1.1 24.0 48.2 70.9 15.1 40.6 7.3 1.9 15.5 5.8 9.4 16.7 8.7 18.9 55.2 49.6 18.6 4.8 16.8 9.4 48.2 47.2 12.5 5.7 5.4 28.4 8.3 48.2 18.2 2.6 8.6 7.2 7.2 6.4 7.5 8.3 9.4 47.4 16.3 10.9 6.1 50.2 3.5 11.0 5.8 6.1 11.6 12.3 51.0 2.8 6.8 7.4 27.8 9.5 14.3 0.2 10.2 7.4 6.8 2.7 2.8 5.2 0.0 8.7 9.9 11.3 6.9 4.9 4.2 0.5 13.9 3.4 10.1 10.4 0.6 10.9 2.5 15.0 19.9 12.3 1.9 0.8 7.7 15.2 10.6 8.1 26.8 6.9 12.4 0.5 9.4 0.6 8.4 7.7 26.7 0.1 9.9 10.3 0.0 6.8 18.4 9.0 3.7 7.7 0.9 12.2 7.9 24.0 20.4 16.5 1.5 3.7 1.2 3.2 11.8 10.4 2.9 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 52.3 56.0 48.2 70.9 55.2 49.6 48.2 47.2 48.2 47.4 50.2 51.0 29.5 0.0 1.1 16.6 2.2 1.9 1.8 3.2 8.0 3.3 1.1 1.5 6.6 1.5 1.7 0.0 6.2 0.0 1.8 0.1 1.9 1.0 4.7 0.6 1.8 21.1 0.0 0.4 15.8 0.2 0.4 2.7 0.5 1.7 0.0 0.1 20.0 2.1 0.3 0.0 3.6 0.2 2.0 1.3 2.1 9.7 3.1 0.5 5.4 13.1 0.1 5.9 0.0 1.0 0.9 0.7 0.0 2.2 1.6 2.9 0.0 1.9 1.3 11.4 0.0 0.6 1.8 1.3 3.2 1.8 1.3 0.0 3.3 0.7 0.1 1.1 MAPK12 "ERK6, p38gamma, PRKM12, SAPK-3, SAPK3" ENSG00000188130 "Mitogen-activated protein kinase 12" P53778 22 50245450-50261716 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "skeletal muscle: 279.7;tongue: 120.9" "Cell type enhanced" "Detected in many" "Adipocytes: 23.1;Astrocytes: 22.9;Endothelial cells: 15.8;Hepatic stellate cells: 20.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 31.6" "Low region specificity" "Detected in all" "CAB025483, HPA054562" Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" Cytosol "CAB025483: , HPA054562: AB_2682524" "unprognostic (3.68e-2)" "unprognostic (1.72e-1)" "unprognostic (4.53e-3)" "unprognostic (1.54e-1)" "unprognostic (3.22e-2)" "unprognostic (6.35e-3)" "unprognostic (3.90e-3)" "unprognostic (3.16e-2)" "unprognostic (6.02e-2)" "unprognostic (5.70e-2)" "unprognostic (3.48e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.00e-6)" "unprognostic (2.57e-1)" "unprognostic (8.88e-2)" "unprognostic (1.11e-2)" "unprognostic (4.28e-3)" 11.0 2.3 15.6 3.8 16.5 1.3 7.9 15.5 21.2 11.4 9.2 4.7 3.5 19.0 9.8 6.3 11.2 4.4 15.7 15.1 16.5 10.7 1.4 6.8 4.1 17.1 14.9 10.6 1.8 4.3 25.1 4.1 14.6 10.0 1.1 1.4 4.3 6.9 279.7 1.5 4.4 8.6 14.6 4.3 5.0 4.6 15.2 0.9 3.2 120.9 1.4 6.0 5.9 13.9 23.2 13.9 5.3 16.3 12.4 13.5 7.5 17.5 15.1 28.2 18.3 19.6 7.2 45.1 23.4 19.6 16.8 15.4 24.3 3.4 5.5 12.8 34.0 29.2 46.7 24.9 37.7 28.4 54.5 29.8 6.0 7.2 0.0 16.8 33.2 4.0 26.3 38.5 13.4 12.8 0.0 35.4 15.9 7.6 22.5 41.4 14.2 43.9 17.5 3.0 18.0 6.5 13.3 0.5 22.1 4.2 7.1 29.6 18.7 28.5 26.1 6.6 11.2 9.3 7.3 24.5 7.2 24.7 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 15.6 16.5 15.5 21.2 15.1 16.5 17.1 14.9 14.6 14.6 15.2 13.9 23.1 0.0 3.2 22.9 1.6 0.8 0.7 3.3 1.2 5.5 1.2 1.3 8.8 4.3 0.8 0.0 0.0 0.3 0.9 0.3 1.9 0.5 0.3 0.6 10.0 15.8 1.8 1.7 9.8 0.0 2.8 5.3 2.6 0.7 10.8 0.6 20.7 0.9 6.3 1.7 6.5 0.2 8.2 2.2 0.8 1.9 6.5 2.2 0.0 6.5 0.6 8.1 0.0 5.0 0.9 0.5 0.0 3.8 2.8 3.6 0.4 8.0 0.9 2.2 6.6 3.3 3.0 0.7 12.1 0.8 0.6 0.4 2.2 3.2 0.3 0.2 MARCHF8 "c-MIR, CMIR, MARCH-VIII, MARCH8, MIR, RNF178" ENSG00000165406 "Membrane associated ring-CH-type finger 8" Q5T0T0 10 45454585-45594906 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 26.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014597 Approved NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA014597: AB_1853580" "unprognostic (1.38e-1)" "unprognostic (3.69e-2)" "unprognostic (1.74e-1)" "unprognostic (1.68e-3)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "unprognostic (3.51e-1)" "unprognostic (2.58e-1)" "unprognostic (1.56e-2)" "unprognostic (2.04e-1)" "prognostic favorable (2.71e-4)" "unprognostic (1.28e-1)" "prognostic favorable (6.64e-4)" "unprognostic (1.01e-1)" "unprognostic (1.24e-1)" "unprognostic (1.85e-1)" "unprognostic (3.12e-2)" 14.3 19.2 11.8 12.4 18.5 49.1 16.8 19.3 13.1 13.8 11.7 21.3 14.2 14.4 10.4 10.6 15.3 13.4 20.5 11.1 13.1 15.5 16.9 15.0 16.9 18.8 14.2 19.5 26.5 19.8 16.0 12.2 17.3 11.5 18.3 18.2 14.8 15.2 14.7 10.5 22.4 13.8 14.7 18.7 14.4 57.1 16.1 17.8 16.3 15.4 20.3 11.4 9.0 26.7 16.6 16.4 13.7 12.4 19.4 24.2 10.1 7.5 35.0 13.6 14.8 4.2 16.8 23.8 12.6 21.9 12.3 3.0 15.2 12.4 12.6 36.3 16.7 9.2 7.4 10.0 13.6 11.3 39.1 19.8 16.3 6.8 17.9 13.4 22.5 22.4 26.5 23.2 10.5 5.8 11.5 7.1 4.5 2.4 5.3 12.7 13.7 7.0 10.2 9.5 12.2 17.0 14.7 3.5 14.0 13.3 21.2 5.2 15.1 10.6 13.6 15.6 12.0 39.8 34.2 10.5 21.0 15.5 2.9 13.9 1.1 10.8 3.0 1.9 4.5 3.5 3.4 3.3 1.6 5.4 2.5 3.2 14.1 8.5 0.9 1.6 3.6 2.5 11.8 18.5 19.3 13.1 11.1 13.1 18.8 14.2 17.3 14.7 16.1 26.7 6.1 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.0 0.0 2.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 1.7 2.8 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 1.6 1.3 0.0 0.0 0.0 MARCKSL1 "F52, MacMARCKS, MLP, MLP1" ENSG00000175130 "MARCKS like 1" P49006 1 32333839-32336233 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 712.7" "Cell type enhanced" "Detected in many" "monocytes: 941.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 8 "eosinophil: 252.7" "Lineage enriched" "Detected in all" 8 "granulocytes: 252.7" "Cell line enhanced" "Detected in many" "AF22: 1016.3;NTERA-2: 984.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020787, HPA030528" Enhanced Supported "Nucleoplasm,Actin filaments,Cytosol" NA Yes 170000 "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 5: NTERA-2 - Transcription" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "Nucleoplasm, Actin filaments" "CAB020787: , HPA030528: AB_2673514" "unprognostic (8.08e-2)" "unprognostic (1.28e-1)" "unprognostic (1.11e-1)" "unprognostic (1.04e-2)" "unprognostic (1.38e-1)" "unprognostic (3.16e-3)" "prognostic unfavorable (1.78e-6)" "unprognostic (3.65e-1)" "unprognostic (1.72e-1)" "unprognostic (8.41e-3)" "unprognostic (2.91e-1)" "unprognostic (1.76e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (1.50e-1)" "unprognostic (8.16e-3)" "unprognostic (1.08e-1)" "unprognostic (3.22e-2)" 63.4 59.9 363.5 82.1 510.3 50.1 102.9 540.1 438.2 81.2 206.4 108.1 61.8 93.4 155.8 15.1 72.2 97.2 55.0 343.0 408.0 51.1 38.7 40.0 176.0 631.5 504.7 358.0 23.7 6.5 22.9 42.9 534.9 84.7 116.5 37.9 75.9 49.9 8.7 28.3 56.1 42.7 467.9 63.1 132.8 139.2 466.4 166.0 110.3 11.0 199.5 77.8 27.1 712.7 82.9 73.3 1016.3 418.6 22.5 8.3 181.0 34.0 21.2 99.9 66.0 176.0 59.9 185.7 124.4 23.2 0.3 43.0 333.1 3.8 73.3 4.5 246.5 10.0 27.0 392.4 68.7 48.8 0.9 114.8 13.7 75.0 2.1 154.2 295.0 312.6 291.5 2.2 135.7 197.5 613.5 205.9 984.3 267.4 168.1 754.8 109.4 87.7 152.1 163.1 629.0 597.8 178.8 194.2 587.8 411.9 135.4 85.8 87.8 41.8 241.3 3.9 66.1 27.8 2.3 489.8 4.7 73.6 225.7 3.1 4.0 252.7 3.8 23.1 1.4 20.0 7.4 4.9 6.6 27.7 15.3 6.4 18.2 1.1 30.3 9.0 4.8 4.9 363.5 510.3 540.1 438.2 343.0 408.0 631.5 504.7 534.9 467.9 466.4 712.7 242.5 0.0 1.3 27.1 191.1 93.7 114.7 43.5 40.5 27.7 465.7 385.8 8.5 178.7 68.8 60.7 6.2 16.1 110.1 194.1 82.2 389.7 37.4 68.7 190.3 326.9 746.2 74.4 4.2 307.2 116.4 124.3 246.2 115.2 22.3 378.6 462.3 5.3 21.2 10.1 21.9 514.2 236.0 61.0 365.3 66.7 613.3 82.0 300.6 9.4 941.4 464.3 46.4 93.0 428.3 751.6 292.8 641.3 39.5 418.8 30.2 9.8 15.6 14.8 131.5 40.3 210.0 14.8 102.7 22.5 83.1 13.4 89.8 172.0 447.1 586.9 MARK2 "EMK1, PAR-1, PAR-1B, Par1b" ENSG00000072518 "Microtubule affinity regulating kinase 2" Q7KZI7 11 63838928-63911020 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038790, HPA074905" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "HPA038790: AB_10674840, HPA074905: AB_2686722" "unprognostic (1.33e-2)" "unprognostic (2.45e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.21e-4)" "unprognostic (7.13e-2)" "unprognostic (3.82e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (2.73e-3)" "unprognostic (4.41e-1)" "unprognostic (5.79e-2)" "unprognostic (3.94e-3)" "unprognostic (3.77e-1)" "unprognostic (5.20e-3)" "unprognostic (5.15e-3)" "unprognostic (6.78e-2)" "unprognostic (1.03e-1)" "unprognostic (2.40e-1)" 11.3 13.8 12.6 21.1 16.1 24.0 16.8 8.1 16.3 18.5 10.8 25.9 26.1 14.6 7.7 51.8 16.6 14.1 20.9 14.9 9.3 13.9 13.1 17.0 21.5 11.8 9.3 12.0 22.4 19.4 19.8 14.9 11.5 20.5 22.4 8.8 27.0 13.1 20.8 40.9 25.1 16.3 7.3 24.1 20.9 10.6 9.5 23.2 19.5 13.7 24.0 19.3 25.0 17.9 52.0 34.1 26.6 28.6 14.6 18.6 35.2 20.8 20.0 29.5 22.3 34.1 49.5 37.8 35.6 20.8 32.0 57.5 26.9 28.7 24.6 26.7 20.9 40.7 23.9 20.3 17.0 45.9 51.4 10.9 36.8 27.0 21.4 13.5 24.7 33.6 35.7 36.5 19.5 64.4 49.3 29.9 31.7 36.0 24.2 39.9 20.4 39.7 19.1 39.8 37.9 25.4 34.7 90.2 24.3 28.9 65.1 26.4 22.7 30.3 19.1 39.6 23.4 24.5 28.8 36.7 20.1 23.2 25.3 1.4 0.7 2.1 1.3 0.7 2.1 0.9 1.0 1.3 1.0 1.6 0.8 0.9 3.6 1.6 1.1 0.9 0.6 0.7 12.6 16.1 8.1 16.3 14.9 9.3 11.8 9.3 11.5 7.3 9.5 17.9 17.3 6.4 6.8 29.7 18.5 25.2 21.1 9.1 19.4 26.8 30.0 18.2 12.8 27.1 11.9 20.2 8.4 26.0 33.4 90.3 1.9 20.2 0.6 29.5 15.8 14.7 29.9 14.7 43.6 21.4 20.6 11.7 27.0 41.0 17.2 21.1 13.6 13.0 17.9 20.2 30.3 39.9 10.2 26.7 18.5 0.9 12.8 25.0 3.6 29.0 17.0 18.8 36.0 31.7 51.8 27.3 39.4 10.9 15.6 30.4 33.4 8.1 14.5 18.1 19.7 19.6 13.1 9.1 18.4 39.9 34.4 65.0 23.6 16.0 33.6 44.3 MARVELD2 "DFNB49, FLJ30532, MRVLDC2, TRIC" ENSG00000152939 "MARVEL domain containing 2" Q8N4S9 5 69415065-69444330 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 15.7" "Cell type enhanced" "Detected in many" "Urothelial cells: 46.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 29.5;CAPAN-2: 24.1;HaCaT: 18.9;RT4: 21.1;SCLC-21H: 26.7;T-47d: 18.3" "Region enriched" "Detected in some" 8 "cerebellum: 7.9" "Low region specificity" "Detected in all" "HPA018119, HPA061726" Uncertain Supported "Cell Junctions" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "HPA018119: AB_2669771, HPA061726: AB_2684595" "unprognostic (4.11e-2)" "unprognostic (3.05e-1)" "unprognostic (1.22e-2)" "unprognostic (2.44e-3)" "unprognostic (1.68e-1)" "unprognostic (1.17e-1)" "unprognostic (2.49e-1)" "unprognostic (8.84e-2)" "unprognostic (2.43e-1)" "unprognostic (3.47e-2)" "unprognostic (2.60e-2)" "unprognostic (1.75e-1)" "prognostic favorable (2.84e-13)" "unprognostic (1.78e-1)" "unprognostic (1.19e-1)" "unprognostic (3.67e-2)" "unprognostic (1.82e-1)" 0.3 0.2 0.5 0.9 0.5 0.2 4.0 0.5 0.6 2.1 3.2 5.7 7.7 1.1 1.3 6.9 3.9 2.9 0.4 0.5 0.5 8.0 10.7 5.6 0.1 0.7 0.7 0.1 9.3 4.6 2.9 1.8 0.7 3.0 6.2 0.3 4.6 2.6 0.0 4.3 7.7 0.4 0.4 0.2 8.1 1.5 0.7 1.0 15.7 0.0 1.3 3.0 3.4 0.7 10.8 3.5 0.1 0.0 0.0 0.0 29.5 0.2 0.2 0.2 0.7 14.1 24.1 0.1 2.0 1.8 0.0 18.9 0.0 14.0 0.5 0.2 5.8 0.0 1.1 7.8 1.7 0.0 0.1 0.4 15.3 0.1 1.9 0.7 0.9 0.1 0.0 0.1 0.0 9.8 0.0 0.0 1.8 6.3 0.3 0.0 0.1 0.5 10.0 21.1 26.7 0.0 2.3 2.0 0.3 4.3 18.3 0.0 1.5 0.0 0.1 0.0 0.0 0.1 3.5 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.5 0.5 0.5 0.6 0.5 0.5 0.7 0.7 0.7 0.4 0.7 0.7 1.0 22.4 26.5 0.7 1.0 5.0 22.2 14.8 10.2 0.3 15.5 8.5 2.8 35.8 23.1 16.5 2.1 22.9 0.2 31.4 17.6 25.1 5.8 33.5 3.4 4.1 16.8 3.4 0.5 25.8 8.2 1.1 17.9 30.4 1.3 3.7 5.0 37.9 1.9 0.0 0.4 23.1 18.3 0.6 0.9 3.2 0.0 0.6 1.8 1.0 7.8 0.5 0.0 0.5 0.6 25.0 29.7 0.0 0.6 25.5 33.5 6.1 38.4 0.6 0.0 0.8 1.5 4.1 2.4 19.4 6.5 12.0 0.9 2.9 25.6 46.9 MARVELD3 MRVLDC3 ENSG00000140832 "MARVEL domain containing 3" Q96A59 16 71626161-71642114 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 150.1;Intestinal goblet cells: 68.2;Paneth cells: 102.9;Proximal enterocytes: 199.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "basophil: 1.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 21.7;BEWO: 30.9;CACO-2: 23.6;CAPAN-2: 22.5;HaCaT: 21.4;MCF7: 40.8;RT4: 18.8;SK-BR-3: 18.5;T-47d: 26.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043514, HPA045471" Approved "Vesicles,Intermediate filaments" No NA "Cluster 17: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 45: Enterocytes - Digestion" Vesicles "Intermediate filaments" "HPA043514: AB_10959475, HPA045471: " "unprognostic (1.18e-1)" "unprognostic (3.92e-1)" "unprognostic (9.92e-2)" "unprognostic (5.56e-2)" "unprognostic (1.03e-1)" "unprognostic (6.16e-3)" "unprognostic (2.04e-1)" "unprognostic (3.22e-2)" "unprognostic (2.54e-1)" "unprognostic (8.75e-3)" "unprognostic (3.29e-1)" "unprognostic (5.16e-2)" "prognostic favorable (6.80e-10)" "unprognostic (2.63e-3)" "unprognostic (4.76e-1)" "unprognostic (3.59e-2)" "unprognostic (2.43e-1)" 0.2 0.3 0.5 3.1 0.6 0.6 6.2 1.8 0.9 4.0 6.5 23.6 31.1 1.8 7.3 4.2 4.2 4.8 0.3 1.1 0.5 12.9 5.3 2.4 0.5 0.4 0.5 0.5 17.1 12.5 1.0 5.7 0.5 6.0 18.7 2.1 11.6 2.5 0.8 3.3 33.1 0.6 0.1 0.4 2.8 0.9 0.5 0.9 3.9 0.0 1.7 3.8 2.5 0.9 21.7 0.7 0.5 0.9 0.0 0.1 30.9 0.0 0.0 0.0 0.0 23.6 22.5 0.2 2.3 0.0 0.1 21.4 1.9 10.3 0.1 0.0 12.1 0.0 0.4 6.2 0.0 0.1 0.2 0.9 12.5 0.1 0.2 0.1 0.0 0.1 0.3 0.1 0.0 40.8 0.2 0.3 3.5 13.4 0.2 0.0 0.1 8.8 0.3 18.8 3.7 0.2 0.4 18.5 0.0 2.4 26.3 0.3 0.0 0.0 0.4 0.4 0.2 0.2 0.3 0.1 0.2 0.2 0.2 1.8 0.2 0.2 0.2 0.1 0.1 0.2 0.2 0.2 0.1 0.4 0.2 0.2 1.2 0.4 0.1 0.3 0.2 0.1 0.5 0.6 1.8 0.9 1.1 0.5 0.4 0.5 0.5 0.1 0.5 0.9 0.3 9.6 8.4 0.3 0.8 7.9 28.7 9.6 22.8 7.0 25.4 10.7 0.6 40.0 17.9 9.2 0.0 36.5 1.5 150.1 1.9 29.8 4.4 14.2 1.5 1.0 61.5 0.0 0.6 33.7 2.5 1.5 6.1 19.4 0.0 3.8 0.4 9.1 3.1 0.0 0.6 68.2 14.2 1.0 1.0 3.3 0.3 1.2 0.0 0.0 0.8 1.0 0.0 0.0 0.6 26.3 102.9 0.7 0.0 38.4 199.3 27.6 17.4 19.6 0.0 4.1 1.6 9.6 5.0 19.6 3.7 4.8 1.4 0.0 61.3 44.3 MBD1 "CXXC3, PCM1" ENSG00000141644 "Methyl-CpG binding domain protein 1" Q9UIS9 18 50266882-50281774 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 97.4;Spermatocytes: 136.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009017, CAB036003, HPA068850" Approved Enhanced Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Vesicles" "CAB009017: AB_2095559, CAB036003: , HPA068850: AB_2732121" "unprognostic (2.12e-2)" "unprognostic (5.05e-2)" "unprognostic (6.88e-2)" "unprognostic (5.01e-3)" "unprognostic (9.20e-2)" "unprognostic (6.85e-2)" "prognostic unfavorable (5.08e-6)" "unprognostic (5.91e-2)" "unprognostic (2.61e-2)" "unprognostic (4.65e-2)" "unprognostic (1.96e-3)" "prognostic unfavorable (1.70e-6)" "unprognostic (7.06e-3)" "unprognostic (7.70e-2)" "unprognostic (7.05e-2)" "unprognostic (4.61e-2)" "unprognostic (1.31e-1)" 28.5 39.8 23.9 26.2 25.9 44.2 29.1 24.8 28.2 32.3 19.3 35.7 24.8 32.1 20.5 39.2 31.6 19.6 35.7 26.7 22.2 32.5 35.7 29.9 30.2 23.1 22.0 34.8 34.5 32.4 42.8 24.6 21.1 33.0 17.7 24.0 30.5 23.5 51.0 43.4 33.7 20.4 19.5 41.0 33.6 88.1 23.1 29.6 35.4 28.6 24.2 35.3 32.2 25.6 30.9 28.6 31.5 35.9 33.2 26.9 33.9 36.2 41.4 49.2 37.7 21.6 23.9 48.5 25.8 35.3 28.8 54.4 36.3 63.4 28.4 54.7 23.2 30.6 43.8 23.1 63.9 74.8 62.1 31.5 100.4 56.2 127.2 31.1 40.9 47.4 39.3 73.8 38.3 28.5 63.3 38.9 29.8 16.1 22.7 57.8 23.3 53.2 24.4 13.8 41.5 39.5 27.0 25.5 33.2 25.4 32.4 67.4 44.7 53.0 24.1 17.3 37.2 135.8 62.2 51.6 34.3 56.8 49.0 16.0 11.2 22.7 15.3 9.7 14.6 11.6 13.5 12.9 11.2 11.4 13.8 11.4 14.5 14.3 7.8 10.2 13.8 12.6 23.9 25.9 24.8 28.2 26.7 22.2 23.1 22.0 21.1 19.5 23.1 25.6 17.7 9.6 24.6 19.6 20.1 22.7 13.9 18.2 23.3 15.1 16.5 14.5 28.1 14.3 20.5 16.5 18.8 31.1 25.0 24.5 13.7 15.7 85.1 17.1 16.1 17.6 13.1 9.7 20.4 13.8 24.2 16.5 28.1 17.3 8.8 17.7 13.9 18.1 18.7 15.2 17.3 19.5 24.4 15.8 11.1 97.4 15.5 17.5 16.0 9.4 15.7 17.4 14.4 12.1 16.4 21.1 24.5 19.2 34.6 14.4 21.3 9.7 16.9 20.3 13.1 14.8 18.9 136.0 32.5 21.6 29.3 51.4 20.0 28.1 18.6 17.0 MBD5 "FLJ11113, KIAA1461" ENSG00000204406 "Methyl-CpG binding domain protein 5" Q9P267 2 148021011-148516971 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 317.4;Excitatory neurons: 510.1;Inhibitory neurons: 456.0;Microglial cells: 288.6;Oligodendrocyte precursor cells: 604.2;Oligodendrocytes: 438.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035964 Supported Nucleoplasm,Midbody Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Midbody" "HPA035964: AB_2674891" "unprognostic (1.10e-2)" "unprognostic (1.02e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (3.72e-4)" "unprognostic (5.81e-2)" "unprognostic (2.12e-1)" "unprognostic (2.22e-2)" "unprognostic (1.65e-1)" "unprognostic (9.86e-2)" "unprognostic (7.72e-2)" "unprognostic (2.00e-1)" "unprognostic (1.94e-1)" "unprognostic (2.39e-2)" "unprognostic (9.12e-2)" "unprognostic (1.12e-1)" "unprognostic (6.59e-2)" "unprognostic (1.82e-1)" 2.5 3.2 3.7 2.2 4.3 2.0 2.3 7.2 5.1 3.1 0.5 5.2 1.8 3.2 1.6 2.6 2.2 3.2 2.8 3.9 3.1 3.4 2.0 2.3 2.4 2.2 2.2 3.7 1.7 4.1 3.8 3.0 2.1 3.0 1.9 5.7 1.8 2.5 2.8 1.9 2.3 2.7 2.0 2.6 2.7 3.1 3.3 4.2 3.4 3.0 2.2 3.7 2.2 4.1 1.1 1.1 4.4 4.1 3.5 3.6 2.9 4.0 3.9 3.1 2.3 2.8 2.9 1.9 0.9 3.4 1.7 0.8 3.1 5.1 4.1 1.6 1.6 3.5 2.8 1.5 2.0 0.6 0.6 2.9 4.1 4.5 3.3 5.0 4.1 2.7 1.9 3.6 4.8 2.7 1.5 2.7 2.2 2.5 1.7 1.6 1.2 0.8 3.2 3.8 2.9 3.5 3.2 1.6 3.0 3.2 2.3 3.4 2.8 3.7 1.8 0.6 1.9 2.4 1.1 1.5 4.8 1.6 3.6 0.8 0.1 0.5 0.3 0.1 0.2 0.2 0.3 0.3 0.2 0.2 0.3 0.4 0.2 0.2 0.3 0.3 0.1 0.1 3.7 4.3 7.2 5.1 3.9 3.1 2.2 2.2 2.1 2.0 3.3 4.1 27.3 16.0 13.7 317.4 23.4 3.8 11.9 4.1 10.8 24.7 16.5 15.0 10.5 11.5 14.8 12.9 37.5 7.3 23.8 5.0 3.9 18.6 94.5 14.8 25.8 15.2 11.5 36.6 510.1 15.7 9.8 15.5 12.2 18.0 3.8 35.9 15.0 8.4 7.0 13.5 456.0 4.9 6.1 16.9 3.3 37.6 18.0 15.1 0.0 288.6 13.6 8.1 24.7 604.2 438.3 20.4 4.6 10.5 22.8 7.8 9.4 14.0 8.5 17.4 6.6 16.5 16.8 15.7 9.4 10.4 3.3 8.5 27.7 23.7 5.8 12.6 MBL2 "COLEC1, MBL" ENSG00000165471 "Mannose binding lectin 2" P11226 10 52765380-52772784 "Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement activation lectin pathway, Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2810 "liver: 280.9" "Cell type enriched" "Detected in some" 66 "Hepatocytes: 238.5" "Cancer enriched" "Detected in single" 275 "liver cancer: 22.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "Hep G2: 2.2" "Not detected" "Not detected" "Region enriched" "Detected in single" 11 "basal ganglia: 1.1" "HPA002027, CAB016782" Enhanced "Secreted to blood" NA NA 1220000000 1900000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB016782: , HPA002027: AB_1079324" "unprognostic (1.72e-2)" "unprognostic (3.03e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 280.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 238.5 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 MBNL3 "CHCR, FLJ11316, MBLX39, MBXL" ENSG00000076770 "Muscleblind like splicing regulator 3" Q9NUK0 X 132369317-132489968 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 59.3;placenta: 170.8" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 328.3;Hepatocytes: 119.6;Syncytiotrophoblasts: 344.1" "Cancer enhanced" "Detected in all" "liver cancer: 13.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 123.8;Hep G2: 171.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001584 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 28: Placenta - Pregnancy" "Cluster 39: CACO-2 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "Golgi apparatus" "HPA001584: AB_1079326" "unprognostic (3.38e-2)" "unprognostic (1.40e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (1.57e-4)" "unprognostic (1.87e-1)" "unprognostic (2.67e-3)" "unprognostic (8.74e-2)" "unprognostic (3.46e-2)" "unprognostic (2.19e-2)" "unprognostic (5.77e-3)" "unprognostic (4.36e-3)" "unprognostic (1.65e-1)" "unprognostic (1.07e-1)" "unprognostic (1.67e-1)" "unprognostic (2.43e-1)" "unprognostic (8.28e-2)" "unprognostic (2.37e-1)" 6.8 11.6 1.3 8.7 1.9 14.8 4.7 1.7 1.0 3.7 2.4 11.7 9.9 4.9 24.3 10.9 9.4 5.7 9.7 1.1 4.4 8.0 59.3 5.9 13.8 3.6 3.1 4.8 10.0 4.2 1.6 170.8 3.2 4.0 11.5 0.1 6.6 11.1 0.6 12.6 9.8 4.0 2.0 11.3 13.0 42.8 1.6 14.3 8.2 3.4 15.1 8.5 2.8 3.7 7.2 0.0 8.6 1.4 1.6 3.6 15.7 0.5 3.2 1.1 0.0 123.8 22.7 32.6 0.7 1.3 1.1 7.7 19.8 8.2 0.8 3.3 7.6 29.1 25.9 171.5 1.5 32.9 10.2 1.5 7.1 0.0 3.6 0.1 1.1 20.4 2.6 9.2 1.6 19.2 56.3 12.5 1.3 27.5 1.6 53.2 10.7 18.6 5.7 18.6 3.1 10.5 14.8 8.6 4.3 15.1 3.1 8.4 3.9 6.3 1.2 8.2 6.7 18.2 13.0 47.0 1.2 21.8 20.2 11.9 7.9 5.5 16.6 9.9 14.4 20.6 9.8 11.6 8.8 25.5 10.0 11.2 1.2 18.7 21.7 17.0 2.2 9.1 1.3 1.9 1.7 1.0 1.1 4.4 3.6 3.1 3.2 2.0 1.6 3.7 4.1 3.2 6.8 16.0 16.9 8.8 2.2 2.1 5.2 0.7 3.5 3.6 14.7 41.5 5.0 11.0 0.0 328.3 9.5 12.8 3.9 1.5 5.8 12.6 1.3 3.6 6.7 55.8 0.9 5.4 56.6 7.5 15.3 6.6 8.8 6.8 6.4 119.6 29.3 0.0 0.9 9.8 0.0 27.2 6.5 9.4 23.0 9.6 7.2 30.0 10.6 0.2 9.2 0.0 20.6 1.3 3.6 50.8 12.2 1.4 6.4 9.7 4.5 1.9 0.0 3.1 2.7 2.1 1.7 13.6 8.5 344.1 10.3 5.7 10.3 3.3 MBTPS2 "KFSD, S2P" ENSG00000012174 "Membrane bound transcription factor peptidase, site 2" O43462 X 21839617-21885423 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Metalloprotease, Protease" "Disease variant, Ichthyosis, Osteogenesis imperfecta, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005494, CAB009486" Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Mitochondria, Cytosol" "CAB009486: AB_2140370, HPA005494: AB_1079329" "unprognostic (7.97e-3)" "unprognostic (9.12e-2)" "unprognostic (5.38e-2)" "unprognostic (1.18e-2)" "unprognostic (2.65e-1)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (7.22e-2)" "unprognostic (3.32e-1)" "unprognostic (9.30e-2)" "unprognostic (1.99e-1)" "unprognostic (1.77e-1)" "unprognostic (8.38e-2)" "unprognostic (7.76e-2)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" "unprognostic (3.05e-2)" 8.6 10.6 3.5 5.2 4.0 1.7 8.8 7.8 4.9 7.5 4.5 5.1 5.2 9.7 6.0 5.8 7.3 6.7 7.7 3.7 4.1 9.4 18.7 5.5 5.0 4.4 4.1 12.5 7.3 11.0 3.8 11.6 4.9 10.5 6.0 8.8 6.6 8.5 7.1 3.7 4.2 10.1 4.1 4.8 5.8 4.1 4.2 4.9 9.0 9.1 4.7 6.8 4.0 6.1 16.9 34.5 16.1 16.5 19.8 24.4 7.7 24.4 24.7 22.7 19.7 13.8 22.5 14.6 12.4 26.2 44.4 15.4 22.4 14.0 27.9 10.9 17.8 7.2 19.7 11.4 27.1 15.6 6.8 23.2 14.8 34.3 25.1 23.0 17.8 8.4 20.3 15.8 26.1 10.5 6.4 8.1 15.0 8.8 25.1 7.9 29.8 16.4 15.7 8.4 3.9 32.8 34.3 21.5 30.5 21.3 28.9 13.2 21.2 28.4 6.6 41.9 18.5 19.1 26.0 6.9 31.6 6.4 28.0 0.0 2.2 0.8 2.2 2.5 2.0 1.9 1.6 2.0 3.6 1.7 2.2 2.6 0.2 2.6 2.6 2.4 3.2 1.7 3.5 4.0 7.8 4.9 3.7 4.1 4.4 4.1 4.9 4.1 4.2 6.1 5.5 9.6 11.5 16.6 5.8 5.5 4.8 7.0 8.0 11.8 7.5 5.1 13.3 8.6 7.1 7.3 18.8 7.0 2.2 3.8 0.0 5.9 0.3 4.0 11.5 5.6 2.4 2.1 16.8 8.9 7.1 10.8 6.1 3.7 10.8 14.5 7.5 18.7 9.4 30.3 25.0 3.4 12.2 9.2 4.0 1.9 10.5 4.8 10.6 11.2 5.0 7.3 3.1 21.6 22.2 6.1 2.4 13.2 9.1 7.4 4.9 7.2 10.7 14.5 0.0 8.6 8.3 2.7 1.5 6.5 2.7 4.8 5.1 12.3 4.3 4.9 MCAM "CD146, HEMCAM, MelCAM, METCAM, MUC18" ENSG00000076706 "Melanoma cell adhesion molecule" P43121 11 119308529-119321521 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 128.5;Endothelial cells: 153.5;Muller glia cells: 89.8;Sertoli cells: 322.1;Smooth muscle cells: 384.6" "Cancer enhanced" "Detected in all" "melanoma: 83.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HUVEC TERT2: 1121.0;TIME: 1107.4;WM-115: 869.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002147, HPA008848" Enhanced Approved "Plasma membrane" NA NA 1900000000 "Cluster 13: T-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "CAB002147: AB_563499, HPA008848: AB_1078445" "unprognostic (6.45e-2)" "prognostic unfavorable (7.61e-4)" "unprognostic (7.03e-2)" "unprognostic (1.22e-2)" "unprognostic (6.67e-2)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (8.42e-2)" "unprognostic (2.09e-2)" "unprognostic (1.45e-1)" "unprognostic (1.58e-1)" "unprognostic (9.39e-2)" "prognostic unfavorable (5.14e-4)" "unprognostic (8.75e-3)" "unprognostic (7.84e-2)" "unprognostic (2.31e-1)" "unprognostic (2.79e-3)" 332.7 30.0 36.6 68.4 46.1 1.2 180.6 45.7 45.3 96.6 25.3 166.3 29.2 175.8 47.0 89.2 136.4 66.8 118.0 35.3 44.7 42.0 10.5 116.4 19.6 59.4 43.1 60.9 22.0 93.9 17.8 168.0 52.2 78.1 32.2 12.2 39.5 148.0 40.7 50.9 73.0 160.9 36.2 35.4 97.7 9.7 50.2 15.5 58.7 37.4 15.4 174.5 79.8 44.8 0.7 5.1 4.7 0.3 21.5 0.3 23.2 3.2 0.3 29.9 13.3 17.9 0.9 1.2 94.5 10.7 44.7 3.2 38.3 8.1 15.0 56.9 14.5 1.2 102.4 19.8 51.0 0.1 0.4 15.2 0.3 40.8 18.7 1.1 1121.0 7.1 38.7 1.5 6.1 0.0 1.2 9.3 19.9 0.2 4.4 0.9 147.8 32.9 27.1 0.0 12.5 3.9 87.1 2.1 249.2 46.2 4.3 0.9 1107.4 3.1 156.7 0.2 89.1 2.4 2.3 0.6 43.1 0.1 869.3 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 36.6 46.1 45.7 45.3 35.3 44.7 59.4 43.1 52.2 36.2 50.2 44.8 128.5 0.0 2.3 1.3 1.4 4.7 0.6 11.1 8.0 1.2 9.9 19.7 65.8 18.6 1.1 0.0 22.9 0.5 2.5 0.1 0.0 17.3 1.7 7.8 14.0 153.5 0.0 0.0 1.4 0.4 38.7 14.1 1.5 10.3 0.0 18.2 60.0 0.6 0.8 0.0 3.5 0.0 0.0 1.3 7.0 0.7 0.9 2.4 21.4 14.0 0.6 89.8 1.0 18.6 45.2 1.6 0.0 25.2 3.1 1.7 0.0 0.9 1.3 4.0 322.1 9.9 384.6 2.1 1.6 1.7 3.3 0.4 9.3 4.9 0.1 1.8 MCCC1 MCCA ENSG00000078070 "Methylcrotonoyl-CoA carboxylase 1" Q96RQ3 3 183015218-183116075 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "T-47d: 153.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008310 Approved Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA008310: AB_1853620" "unprognostic (4.01e-2)" "unprognostic (1.83e-3)" "unprognostic (2.05e-2)" "unprognostic (2.59e-3)" "unprognostic (3.46e-2)" "unprognostic (4.16e-2)" "unprognostic (1.69e-1)" "unprognostic (1.10e-3)" "unprognostic (2.57e-3)" "unprognostic (9.82e-2)" "unprognostic (9.74e-2)" "unprognostic (7.65e-2)" "prognostic favorable (3.68e-4)" "unprognostic (4.73e-1)" "unprognostic (2.21e-1)" "unprognostic (2.95e-1)" "unprognostic (1.36e-1)" 37.9 22.6 9.5 9.5 10.9 13.9 33.2 9.9 13.4 12.3 13.8 17.4 16.1 10.1 14.6 17.6 12.2 11.9 34.2 9.2 9.3 58.8 59.3 17.9 11.7 9.5 9.1 17.2 31.2 18.7 8.4 6.3 10.6 15.1 18.6 10.8 18.0 13.4 21.9 12.2 13.8 10.6 9.3 11.8 21.7 9.1 11.1 16.0 18.9 26.3 15.5 26.5 9.4 13.3 43.1 16.5 10.3 10.6 42.6 19.1 20.4 19.5 26.4 21.1 23.5 22.9 17.1 47.6 31.0 17.2 35.8 22.0 15.4 12.9 26.4 16.6 17.0 40.0 18.3 23.9 28.7 27.5 22.0 21.6 14.5 10.0 23.3 14.0 28.6 40.7 22.7 24.7 23.6 35.4 27.1 15.9 11.2 66.3 17.9 22.4 22.6 60.1 32.2 67.2 22.0 16.4 75.3 100.1 21.1 10.7 153.9 37.8 14.0 15.8 12.5 12.8 28.6 24.3 48.8 48.2 16.8 38.4 15.2 14.4 13.3 25.0 10.7 15.6 12.3 17.9 14.1 11.8 26.6 15.4 14.7 13.1 2.1 25.4 16.8 17.3 9.6 10.7 9.5 10.9 9.9 13.4 9.2 9.3 9.5 9.1 10.6 9.3 11.1 13.3 6.2 9.6 53.9 44.7 14.6 7.0 20.1 17.9 15.9 13.0 10.6 9.5 32.8 31.5 20.2 27.6 10.4 35.4 6.3 7.2 33.2 25.3 5.4 11.0 10.2 6.6 6.0 10.9 66.6 17.2 5.4 10.3 21.4 21.9 7.6 19.0 6.1 36.5 16.5 8.4 56.9 13.6 16.2 11.1 8.6 5.5 8.7 10.5 7.2 44.0 10.5 12.0 4.1 47.7 61.6 13.4 15.8 10.5 12.5 10.4 13.5 40.6 21.4 11.2 6.6 11.6 9.6 8.1 4.4 22.3 5.8 28.3 10.1 24.3 20.5 21.7 MEF2A "RSRFC4, RSRFC9" ENSG00000068305 "Myocyte enhancer factor 2A" Q02078 15 99565417-99716466 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 262.8;Microglial cells: 708.3;Oligodendrocytes: 264.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004499, HPA046597" Approved Supported Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB004499: AB_627921, HPA046597: AB_2679714" "unprognostic (1.89e-1)" "unprognostic (8.82e-2)" "unprognostic (5.91e-2)" "unprognostic (8.04e-2)" "unprognostic (8.68e-2)" "unprognostic (2.05e-1)" "unprognostic (2.25e-1)" "unprognostic (6.26e-2)" "unprognostic (1.93e-2)" "unprognostic (1.91e-2)" "unprognostic (7.08e-3)" "unprognostic (1.46e-1)" "prognostic favorable (6.93e-4)" "prognostic unfavorable (7.96e-4)" "unprognostic (4.69e-2)" "unprognostic (1.32e-1)" "unprognostic (1.69e-3)" 32.8 22.9 18.7 20.3 25.4 18.3 22.1 16.4 27.6 27.7 12.9 23.5 12.8 34.5 23.8 21.7 21.8 22.6 89.7 21.9 12.1 24.8 24.5 30.4 25.0 17.4 20.7 30.1 12.8 37.6 9.8 26.4 15.4 23.0 15.0 24.2 19.5 23.7 61.5 54.8 17.6 35.7 18.4 27.2 17.8 15.0 28.4 23.3 19.7 81.9 22.9 22.5 16.6 25.7 17.9 10.1 16.7 8.5 20.7 26.3 8.2 17.8 40.8 14.4 19.5 10.4 24.4 22.3 24.5 38.6 22.1 19.3 17.1 14.1 18.6 15.3 24.8 45.2 22.3 9.4 35.4 18.1 21.3 17.6 23.2 19.3 39.7 59.6 26.5 18.3 16.3 41.6 27.0 7.4 29.7 26.3 8.9 11.9 14.6 43.3 36.1 18.5 29.5 24.9 10.7 14.8 27.2 11.6 51.0 17.6 11.0 16.4 43.7 39.8 21.9 19.9 21.7 22.6 27.8 48.5 27.8 19.6 38.7 7.7 12.1 14.3 3.9 15.6 3.3 15.8 3.6 3.6 13.3 12.1 5.0 3.9 10.8 6.5 19.3 7.8 2.6 5.6 18.7 25.4 16.4 27.6 21.9 12.1 17.4 20.7 15.4 18.4 28.4 25.7 152.7 80.1 43.9 113.9 87.2 88.6 31.7 26.9 62.0 52.0 31.6 37.0 175.8 20.0 40.7 29.5 50.1 7.7 32.9 26.5 25.4 18.0 10.4 80.3 60.6 100.6 12.7 24.8 262.8 18.8 3.4 61.5 34.7 130.7 31.0 30.5 50.3 41.0 39.5 30.3 174.9 17.2 12.2 107.5 63.1 7.8 55.9 104.1 35.6 708.3 65.8 25.2 23.7 157.3 264.4 26.8 22.6 64.7 55.6 27.0 18.9 19.7 51.7 44.9 72.3 62.4 69.4 29.9 29.6 29.4 50.4 9.2 27.8 28.8 17.9 26.8 MEGF9 EGFL5 ENSG00000106780 "Multiple EGF like domains 9" Q9H1U4 9 120600811-120714470 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 68.2" "Cell type enhanced" "Detected in many" "Astrocytes: 143.0;Cone photoreceptor cells: 212.7;Oligodendrocytes: 240.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 25.2" "Group enriched" "Detected in many" 5 "granulocytes: 25.2;monocytes: 7.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014319, HPA050238" Approved Approved Nucleoplasm,Cytosol NA NA 96000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm Cytosol "HPA014319: AB_1848035, HPA050238: AB_2681060" "unprognostic (1.18e-1)" "unprognostic (5.33e-2)" "unprognostic (1.84e-1)" "unprognostic (1.75e-2)" "unprognostic (3.30e-1)" "unprognostic (3.68e-1)" "unprognostic (2.31e-1)" "unprognostic (2.29e-2)" "unprognostic (3.63e-2)" "unprognostic (1.13e-2)" "unprognostic (5.92e-2)" "unprognostic (4.97e-2)" "prognostic favorable (5.48e-11)" "unprognostic (1.90e-2)" "unprognostic (1.50e-1)" "unprognostic (6.78e-2)" "unprognostic (1.41e-1)" 18.1 10.1 24.1 11.5 28.7 18.8 13.6 28.7 26.1 12.0 4.8 7.2 7.0 6.3 5.6 14.0 14.0 8.5 6.4 26.0 34.4 13.5 38.7 20.3 6.5 37.2 33.6 9.7 5.6 11.5 5.3 5.1 27.3 8.7 6.0 68.2 7.7 6.6 7.3 21.5 7.2 8.9 28.2 15.2 8.0 3.3 34.0 5.6 28.4 8.5 6.2 9.7 7.4 37.3 5.0 19.4 16.7 5.2 22.6 13.9 5.3 5.0 4.4 1.3 1.8 1.1 2.9 18.6 7.4 4.8 6.0 21.2 24.1 8.7 3.6 15.2 6.9 2.5 34.1 8.1 9.6 7.5 15.3 6.5 26.1 8.2 6.6 46.0 11.8 9.9 6.0 8.6 13.9 14.4 14.8 2.7 0.7 11.1 5.2 11.2 18.6 7.9 34.0 16.1 16.4 13.9 6.0 4.8 14.7 2.7 14.5 7.5 13.9 5.0 2.8 18.4 7.7 15.5 19.5 6.0 7.0 8.7 28.8 0.6 7.4 5.1 0.8 2.5 0.3 0.4 0.7 0.6 3.0 0.4 0.6 0.5 25.2 0.5 4.5 0.2 0.7 1.9 24.1 28.7 28.7 26.1 26.0 34.4 37.2 33.6 27.3 28.2 34.0 37.3 6.5 86.6 65.0 143.0 8.4 27.4 5.6 8.4 25.0 31.5 30.3 12.8 28.2 14.3 15.6 23.9 212.7 0.5 10.8 7.5 0.0 4.0 0.9 11.8 5.8 7.6 6.6 18.9 85.9 5.4 1.9 10.3 14.3 19.3 7.0 8.4 10.0 48.0 5.8 13.5 63.8 4.7 16.2 45.2 13.9 2.7 11.5 41.3 26.6 22.5 107.2 30.9 13.4 93.0 240.7 13.8 8.6 11.7 11.5 8.3 7.4 6.6 6.1 75.4 13.1 26.5 9.3 14.8 7.3 41.3 43.9 1.2 11.4 4.8 5.5 6.2 MEIS2 "HsT18361, MRG1" ENSG00000134138 "Meis homeobox 2" O14770 15 36889204-37101299 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 522.3;Cone photoreceptor cells: 254.4;Excitatory neurons: 164.7;Hepatic stellate cells: 207.4;Oligodendrocyte precursor cells: 262.4;Oligodendrocytes: 219.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "basophil: 2.9;eosinophil: 2.4" "Lineage enriched" "Detected in single" 29 "granulocytes: 2.9" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 114.0;SH-SY5Y: 104.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 68.4;olfactory bulb: 177.4" "HPA003256, CAB004999" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Cytosol "CAB004999: AB_425545, HPA003256: AB_1079356" "unprognostic (4.33e-2)" "unprognostic (1.94e-2)" "unprognostic (6.71e-4)" "unprognostic (2.47e-3)" "unprognostic (1.65e-1)" "unprognostic (2.24e-1)" "unprognostic (5.23e-2)" "unprognostic (1.23e-1)" "unprognostic (3.66e-1)" "unprognostic (4.73e-2)" "unprognostic (7.97e-2)" "unprognostic (1.11e-1)" "prognostic unfavorable (2.64e-7)" "unprognostic (6.47e-2)" "unprognostic (8.15e-2)" "unprognostic (8.79e-5)" "unprognostic (1.15e-1)" 11.1 21.9 14.4 5.3 50.4 0.0 7.4 11.7 24.9 20.9 0.6 33.2 20.6 37.0 4.1 14.2 23.3 17.8 15.7 16.0 14.7 11.1 6.9 8.4 3.4 19.2 25.7 21.1 13.4 3.5 16.4 8.6 20.0 37.7 6.4 18.8 56.8 21.6 0.7 4.4 8.3 36.3 18.0 7.6 14.1 1.6 11.8 11.1 5.4 9.5 3.4 25.6 13.5 20.3 13.3 12.0 15.3 43.6 16.7 20.6 3.6 28.3 15.6 32.9 18.4 17.2 10.8 7.6 0.7 114.0 20.8 22.4 26.9 7.2 18.1 10.9 17.3 58.8 15.8 13.9 28.6 17.5 57.2 27.3 6.3 22.3 6.6 43.2 19.1 2.8 20.1 0.1 6.4 14.3 0.1 6.7 0.2 15.8 3.9 0.0 11.1 4.1 0.0 25.7 11.9 104.0 10.8 7.1 8.0 16.5 3.4 13.3 27.3 37.6 4.6 10.1 12.1 7.5 8.1 14.6 44.3 9.7 9.6 2.9 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 50.4 11.7 24.9 16.0 14.7 19.2 25.7 20.0 18.0 11.8 20.3 6.5 0.0 7.3 522.3 3.4 17.5 97.3 14.1 79.1 43.8 21.0 16.3 23.9 77.2 11.4 1.8 254.4 23.3 1.0 1.0 0.0 58.4 15.2 10.5 17.1 67.2 1.8 5.3 164.7 27.1 10.0 61.7 25.5 0.8 63.3 14.9 207.4 9.6 3.4 3.3 5.0 0.4 30.5 6.5 6.1 7.4 47.8 1.1 8.8 21.5 0.6 10.7 0.0 262.4 219.7 25.7 0.3 41.3 1.8 38.3 1.4 0.1 26.5 135.9 32.9 14.7 46.4 3.6 3.1 23.8 6.1 4.5 2.3 31.2 1.0 54.1 METTL24 "C6orf186, dJ71D21.2" ENSG00000053328 "Methyltransferase like 24" Q5JXM2 6 110245928-110358272 "Predicted secreted proteins" "Methyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "smooth muscle: 14.2" "Group enriched" "Detected in some" 4 "Astrocytes: 30.0;Excitatory neurons: 23.8;Inhibitory neurons: 28.7;Late spermatids: 8.6;Oligodendrocyte precursor cells: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 3.5" "Lineage enriched" "Detected in single" 29 "T-cells: 3.5" "Cell line enhanced" "Detected in some" "HHSteC: 1.0;SCLC-21H: 1.6;SuSa: 1.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA037441, HPA037442" Uncertain "Secreted - unknown location" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA037441: AB_10670933, HPA037442: AB_10696931" "unprognostic (6.62e-2)" "unprognostic (1.15e-1)" "unprognostic (9.31e-3)" "unprognostic (5.02e-2)" "unprognostic (5.21e-3)" "unprognostic (1.46e-1)" "unprognostic (6.12e-2)" "unprognostic (2.06e-1)" "unprognostic (3.98e-1)" "unprognostic (1.42e-1)" "unprognostic (8.45e-2)" "unprognostic (5.96e-2)" "unprognostic (1.54e-4)" "unprognostic (4.08e-2)" "unprognostic (1.23e-2)" "unprognostic (1.63e-2)" "unprognostic (4.78e-3)" 1.8 1.6 1.4 1.6 2.3 0.0 1.7 2.1 1.9 3.9 8.1 5.9 1.4 7.5 2.2 4.0 6.0 5.8 3.0 1.7 1.8 3.9 0.9 1.6 0.1 1.6 2.2 5.6 1.3 2.5 2.1 0.4 1.4 4.9 4.2 1.4 0.4 7.1 0.0 0.5 2.1 14.2 2.0 0.7 2.4 2.1 1.8 1.0 1.3 1.1 0.6 4.7 1.6 1.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.9 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 2.3 2.1 1.9 1.7 1.8 1.6 2.2 1.4 2.0 1.8 1.2 0.0 0.0 0.0 30.0 0.3 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.9 0.4 1.5 0.1 0.0 0.0 23.8 0.0 0.0 0.8 0.0 0.4 0.0 0.5 0.0 0.0 0.0 1.7 28.7 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 3.7 0.0 0.6 0.0 31.7 5.4 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.3 2.1 0.0 1.0 0.0 0.0 0.3 0.1 0.0 0.0 MFAP2 "MAGP, MAGP-1" ENSG00000117122 "Microfibril associated protein 2" P55001 1 16974502-16980632 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 81.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 197.8;Fibroblasts: 75.8;Granulosa cells: 93.3;Leydig cells: 53.7;Peritubular cells: 63.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 249.4;ASC TERT1: 249.6;HUVEC TERT2: 263.1;SH-SY5Y: 212.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA007354 Enhanced "Secreted to extracellular matrix" NA NA 210000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA007354: AB_1079365" "unprognostic (5.10e-2)" "unprognostic (3.81e-2)" "unprognostic (2.62e-1)" "unprognostic (2.92e-2)" "unprognostic (4.86e-1)" "unprognostic (1.53e-3)" "unprognostic (3.72e-3)" "unprognostic (2.21e-1)" "unprognostic (1.85e-2)" "unprognostic (1.98e-1)" "unprognostic (9.45e-3)" "unprognostic (9.12e-2)" "prognostic unfavorable (2.52e-8)" "unprognostic (2.18e-3)" "unprognostic (1.34e-1)" "unprognostic (1.93e-1)" "unprognostic (5.66e-3)" 36.6 4.2 0.4 13.3 0.6 0.1 22.7 0.5 1.1 81.8 1.6 15.0 5.0 61.4 22.1 6.1 19.0 73.2 13.8 0.5 0.6 9.4 1.6 20.1 4.2 0.7 0.9 35.8 18.8 4.5 13.2 42.4 0.7 22.1 4.8 4.9 16.5 12.1 2.6 27.6 12.1 30.6 0.5 2.7 8.3 11.2 0.7 1.6 9.5 3.0 2.3 22.5 36.7 0.6 0.0 0.2 93.2 0.3 249.4 249.6 6.2 26.3 102.5 39.7 73.7 24.1 1.1 0.0 82.6 89.7 0.1 0.1 7.2 7.7 15.9 0.1 78.0 0.0 37.1 2.1 23.4 0.1 0.1 104.4 18.8 109.4 42.7 113.1 263.1 0.0 0.2 16.2 19.2 12.5 0.1 0.1 108.8 0.5 0.8 1.5 0.0 4.0 0.9 0.3 5.0 212.1 9.0 36.6 9.6 71.1 11.9 13.0 75.6 65.6 128.4 51.7 2.8 0.1 0.3 0.2 53.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.5 1.1 0.5 0.6 0.7 0.9 0.7 0.5 0.7 0.6 5.5 0.0 1.7 0.0 0.1 6.6 7.8 28.7 8.0 0.2 2.1 3.9 0.9 2.8 10.7 3.7 0.0 4.5 0.0 0.1 0.0 1.3 12.9 5.6 28.7 7.1 10.1 0.0 0.0 0.8 197.8 75.8 2.0 8.3 0.0 93.3 1.4 0.0 7.4 0.0 0.0 0.4 12.2 0.0 7.7 7.6 53.7 0.6 17.8 2.8 0.0 27.7 0.0 0.0 0.0 1.9 0.0 63.9 0.5 1.5 0.0 0.0 1.9 0.8 0.0 3.3 14.7 3.2 8.7 0.6 6.3 29.0 0.9 0.5 0.2 1.2 MFAP3L "KIAA0626, NYD-sp9" ENSG00000198948 "Microfibril associated protein 3 like" O75121 4 169986597-170033031 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.5;choroid plexus: 88.8" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1840.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 5.7;eosinophil: 1.8;neutrophil: 3.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 5.7" "Cell line enhanced" "Detected in many" "HMC-1: 22.5;RT4: 38.0;SK-BR-3: 34.3;SuSa: 19.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017986, HPA062306, HPA077490" Enhanced Supported "Nucleoplasm,Cell Junctions" "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Cell Junctions" "HPA017986: AB_1853842, HPA062306: , HPA077490: AB_2686842" "unprognostic (8.04e-3)" "unprognostic (8.67e-3)" "unprognostic (3.74e-1)" "unprognostic (1.28e-2)" "unprognostic (4.51e-2)" "unprognostic (7.92e-2)" "unprognostic (3.50e-2)" "unprognostic (3.14e-2)" "unprognostic (2.67e-1)" "unprognostic (2.33e-1)" "unprognostic (3.96e-1)" "unprognostic (7.58e-2)" "prognostic favorable (1.42e-8)" "unprognostic (6.59e-3)" "unprognostic (2.12e-1)" "unprognostic (1.62e-4)" "unprognostic (2.40e-3)" 2.0 3.4 32.9 0.9 61.0 3.2 12.0 49.1 34.4 13.0 88.8 2.7 0.6 5.1 38.9 0.8 4.2 2.6 1.7 35.2 40.1 30.0 37.4 2.7 0.9 46.3 58.3 0.6 1.5 6.5 4.1 3.0 48.5 2.8 2.0 25.0 2.1 12.8 5.1 24.5 1.0 4.1 38.8 1.5 1.3 46.3 54.9 0.6 2.8 2.3 0.5 10.1 1.8 65.5 0.4 5.7 3.0 3.1 2.6 1.3 1.1 6.2 0.9 2.8 2.5 1.9 0.4 0.0 0.2 9.6 5.4 2.9 10.9 1.4 1.2 0.0 4.7 0.0 6.7 2.4 1.4 0.0 22.5 1.8 3.4 0.3 1.0 1.5 0.3 3.5 0.9 1.1 5.8 3.4 1.0 0.8 3.1 0.7 4.7 0.0 1.8 0.0 8.1 38.0 2.5 5.5 5.1 34.3 11.6 19.1 1.9 0.0 0.2 2.9 11.2 5.5 11.9 0.6 0.0 0.0 7.5 1.2 11.4 5.7 0.1 1.8 0.6 0.7 0.3 0.0 0.5 0.1 0.2 0.0 0.2 0.1 3.5 0.0 0.0 0.5 0.1 4.6 32.9 61.0 49.1 34.4 35.2 40.1 46.3 58.3 48.5 38.8 54.9 65.5 1.0 0.0 5.6 112.6 0.6 2.5 0.4 0.1 2.8 12.2 8.5 9.7 3.4 0.0 0.2 36.8 20.9 3.1 0.2 0.6 5.9 0.5 417.5 8.5 1.1 2.0 2.4 11.2 36.3 1.1 1.0 0.6 0.0 12.4 4.5 11.0 3.3 49.1 1.2 3.3 25.0 0.3 0.0 1.0 0.7 1840.0 5.3 13.5 7.2 3.7 1.5 2.9 2.1 53.8 127.6 1.4 0.3 9.1 0.5 0.9 0.3 24.0 0.3 15.8 19.7 1.7 4.2 17.6 13.2 0.3 8.4 9.4 0.6 1.4 0.8 2.2 MFNG ENSG00000100060 "MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" O00587 22 37469063-37486393 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 69.1" "Cell type enhanced" "Detected in many" "Adipocytes: 51.4;dendritic cells: 54.6;Endothelial cells: 37.1;Hepatic stellate cells: 53.2;Kupffer cells: 45.8;monocytes: 40.6;NK-cells: 72.1;T-cells: 51.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 174.6;HEL: 143.4;HL-60: 220.9;HMC-1: 266.9;HUVEC TERT2: 232.9;TIME: 134.7;U-698: 166.8;U-937: 201.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA048936, HPA056479" Approved Approved Vesicles "Intracellular and membrane" NA NA 74000 "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA048936: AB_2680564, HPA056479: " "unprognostic (1.21e-1)" "unprognostic (4.17e-3)" "prognostic unfavorable (5.12e-4)" "prognostic favorable (1.65e-4)" "unprognostic (6.41e-3)" "unprognostic (1.00e-2)" "unprognostic (2.64e-1)" "unprognostic (2.36e-2)" "unprognostic (4.64e-2)" "unprognostic (2.91e-2)" "unprognostic (5.44e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (2.67e-1)" "unprognostic (4.03e-2)" "unprognostic (3.86e-2)" "unprognostic (1.43e-1)" 22.2 7.1 8.9 37.0 8.9 40.3 14.8 8.4 10.8 8.9 6.4 10.5 8.6 9.7 2.4 7.5 11.0 14.5 14.6 7.9 9.2 9.5 7.1 26.3 69.1 18.1 10.8 3.1 3.9 2.6 3.1 30.3 20.5 6.6 7.8 0.7 5.4 5.7 7.5 5.0 24.0 11.5 10.2 58.9 8.6 2.9 11.0 50.5 9.6 8.8 42.5 13.9 6.2 10.3 6.0 2.2 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.2 7.1 3.0 174.6 0.7 0.0 0.8 10.8 45.1 8.7 0.2 81.6 1.0 143.4 0.6 1.5 0.6 220.9 266.9 0.0 2.6 1.7 3.2 0.9 232.9 69.0 0.7 73.8 0.0 1.5 27.8 3.0 0.4 6.1 1.0 67.0 1.8 128.7 0.4 0.1 94.1 0.9 0.5 0.3 0.3 0.8 1.3 14.1 134.7 0.0 5.8 22.8 0.6 0.4 0.4 166.8 1.1 201.1 2.7 210.3 198.9 386.5 196.1 196.1 214.5 103.0 222.7 206.1 204.1 113.5 243.4 209.9 127.9 217.1 218.7 51.7 284.3 314.0 8.9 8.9 8.4 10.8 7.9 9.2 18.1 10.8 20.5 10.2 11.0 10.3 51.4 0.0 3.8 0.0 35.4 3.7 0.4 0.2 0.0 6.3 1.0 1.3 1.6 5.7 3.1 0.0 0.0 0.3 54.6 1.1 0.0 2.9 0.2 0.4 0.2 37.1 1.2 30.1 0.1 0.9 0.3 1.1 2.0 1.0 31.6 0.1 53.2 1.5 31.9 0.0 0.1 2.1 0.0 45.8 20.2 0.3 0.0 33.5 3.6 6.5 40.6 0.1 72.1 0.0 0.0 3.7 4.0 0.0 35.0 0.5 2.3 0.3 0.1 0.6 0.0 1.6 1.0 0.1 0.7 0.3 2.4 0.7 51.0 0.1 0.8 0.4 MFSD10 "IT10C3, TETRAN" ENSG00000109736 "Major facilitator superfamily domain containing 10" Q14728 4 2930561-2934834 "Predicted membrane proteins" "Apoptosis, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 251.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 275.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043209 Uncertain Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear membrane" Nucleoplasm "HPA043209: AB_2678364" "unprognostic (1.44e-1)" "unprognostic (2.26e-2)" "unprognostic (7.06e-2)" "unprognostic (2.11e-3)" "unprognostic (7.76e-2)" "unprognostic (9.43e-2)" "prognostic unfavorable (4.49e-4)" "unprognostic (6.82e-3)" "unprognostic (4.70e-3)" "unprognostic (3.21e-1)" "unprognostic (1.91e-2)" "unprognostic (5.42e-3)" "prognostic unfavorable (5.68e-5)" "unprognostic (8.32e-2)" "unprognostic (2.30e-1)" "unprognostic (8.03e-2)" "unprognostic (1.00e-2)" 35.2 20.2 15.8 9.9 16.4 66.1 30.5 13.6 24.1 43.1 19.3 30.3 12.3 34.7 3.3 27.6 36.9 12.5 26.5 16.1 14.4 33.6 10.8 36.9 13.2 16.9 14.7 41.6 29.0 3.6 28.7 11.5 14.7 34.3 3.8 1.1 30.4 11.3 14.0 22.0 31.0 7.6 13.2 36.1 31.6 15.6 17.6 6.3 37.6 3.4 6.3 34.6 32.8 14.3 50.4 46.2 13.3 33.7 21.7 15.5 36.0 45.1 21.9 21.5 24.6 24.7 117.3 8.8 23.7 28.4 40.0 45.9 12.1 65.6 5.8 56.9 40.7 19.1 39.2 25.9 36.5 59.9 27.1 23.5 37.5 24.5 15.4 33.4 24.7 20.0 26.4 18.0 16.5 53.8 16.9 275.6 43.0 38.9 54.5 20.7 6.4 41.8 32.9 30.6 34.2 40.7 10.8 31.5 49.1 13.5 82.9 112.9 37.1 17.7 30.4 22.2 36.6 12.2 5.8 13.8 50.0 153.3 27.8 64.7 55.0 117.4 73.0 71.2 62.6 45.1 46.8 82.1 57.4 35.2 23.3 41.1 44.2 45.9 95.8 45.7 34.4 42.6 15.8 16.4 13.6 24.1 16.1 14.4 16.9 14.7 14.7 13.2 17.6 14.3 64.6 38.5 29.1 17.6 41.3 31.4 78.8 251.5 28.5 9.2 56.3 68.1 5.0 28.6 123.2 46.0 8.4 67.4 71.0 37.8 3.9 96.0 11.7 41.5 33.4 41.1 28.2 13.3 21.5 45.9 93.0 42.9 33.6 44.3 32.4 50.7 45.7 3.1 69.6 15.2 14.8 37.2 93.6 49.3 36.7 18.8 36.4 45.6 42.7 9.4 62.1 11.0 64.9 9.5 8.8 86.0 51.5 22.6 28.1 92.1 60.0 17.9 104.9 10.0 92.1 27.0 56.6 15.5 16.1 26.9 26.9 83.7 62.4 44.7 49.4 100.5 MIER2 KIAA1193 ENSG00000105556 "MIER family member 2" Q8N344 19 301444-344815 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041439 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "HPA041439: AB_2677481" "unprognostic (1.48e-1)" "unprognostic (1.45e-3)" "prognostic unfavorable (2.89e-4)" "prognostic favorable (1.72e-5)" "unprognostic (6.71e-2)" "unprognostic (2.96e-1)" "unprognostic (6.95e-3)" "unprognostic (1.96e-2)" "unprognostic (1.43e-1)" "unprognostic (4.24e-1)" "unprognostic (1.18e-2)" "unprognostic (7.24e-2)" "prognostic unfavorable (7.22e-6)" "unprognostic (8.05e-2)" "unprognostic (4.28e-2)" "unprognostic (4.94e-3)" "unprognostic (1.68e-2)" 25.0 13.1 14.0 4.5 12.7 2.1 21.2 10.9 18.8 21.6 7.9 17.3 4.5 22.9 2.9 19.7 16.6 3.2 34.3 12.1 11.6 17.7 8.4 28.1 3.8 13.7 13.0 15.3 11.5 2.3 15.7 6.3 12.6 23.1 1.2 2.0 12.9 4.6 18.1 25.5 14.2 2.8 11.1 33.4 13.4 29.4 12.6 3.4 17.1 7.8 1.8 19.7 19.8 11.6 12.8 7.9 7.0 8.1 2.5 3.7 15.1 10.3 4.8 7.6 7.9 12.3 4.0 6.6 5.4 5.4 3.0 10.7 4.5 6.0 2.3 16.0 21.8 3.9 6.9 9.5 7.5 0.0 30.1 4.8 4.6 6.2 2.2 5.1 8.6 8.8 11.3 0.1 4.3 13.5 10.5 14.3 18.1 3.8 0.0 9.1 2.3 1.8 3.7 7.2 11.2 10.1 6.0 4.5 10.7 4.2 5.1 7.1 9.3 10.3 7.2 15.8 11.6 18.5 9.9 5.5 9.7 5.7 10.4 3.7 3.6 2.5 1.1 3.1 0.9 0.5 1.4 1.6 3.9 1.0 1.8 1.2 0.2 0.9 3.5 2.1 0.7 2.3 14.0 12.7 10.9 18.8 12.1 11.6 13.7 13.0 12.6 11.1 12.6 11.6 28.7 0.0 5.4 4.2 5.0 11.2 11.2 8.8 7.4 7.6 7.7 6.9 1.3 7.2 6.0 3.7 16.7 22.3 3.7 4.4 1.9 9.2 6.4 3.4 6.3 24.1 10.7 6.1 4.9 5.4 19.2 6.9 10.2 4.8 0.0 6.9 7.9 2.3 10.2 3.3 4.4 4.6 4.1 8.5 6.3 19.0 6.2 8.7 5.4 13.1 6.7 7.4 5.2 3.0 6.7 8.5 5.9 5.7 4.5 11.9 3.8 0.9 5.7 12.8 6.6 4.1 5.7 18.4 25.1 6.3 10.7 29.4 5.5 6.5 4.9 12.7 MINDY1 "FAM63A, FLJ11280, MINDY-1" ENSG00000143409 "MINDY lysine 48 deubiquitinase 1" Q8N5J2 1 150996086-151008375 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Distal tubular cells: 39.2;Ductal cells: 11.6;Proximal tubular cells: 12.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 98.4;eosinophil: 56.2;neutrophil: 85.4" "Lineage enriched" "Detected in all" 9 "granulocytes: 98.4" "Cell line enhanced" "Detected in many" "T-47d: 49.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028351, HPA028358, HPA061086" Approved Enhanced Nucleoplasm NA NA 220000 "Cluster 2: Granulocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA028351: AB_10611110, HPA028358: AB_10601102, HPA061086: AB_2684425" "unprognostic (5.73e-2)" "unprognostic (2.86e-1)" "unprognostic (5.47e-2)" "unprognostic (3.14e-1)" "unprognostic (3.39e-2)" "unprognostic (6.90e-2)" "unprognostic (1.47e-2)" "unprognostic (1.64e-1)" "unprognostic (1.02e-1)" "unprognostic (1.88e-1)" "unprognostic (9.22e-3)" "unprognostic (1.06e-1)" "prognostic favorable (3.43e-8)" "unprognostic (2.30e-1)" "unprognostic (7.95e-2)" "unprognostic (2.50e-2)" "unprognostic (6.06e-2)" 13.8 13.0 24.9 8.2 49.9 7.2 15.0 42.7 33.7 19.0 30.9 18.4 16.8 18.1 7.0 37.1 17.4 14.0 33.5 22.2 30.7 30.4 19.0 12.9 6.4 58.7 43.9 21.7 47.6 30.1 15.1 6.8 53.4 14.3 17.2 13.3 29.6 13.7 16.7 20.6 14.8 15.6 33.3 15.1 25.9 23.6 43.1 3.6 47.3 18.0 8.7 15.0 20.1 75.6 11.3 7.3 7.7 10.8 13.4 11.1 6.4 3.6 9.1 5.0 7.9 15.6 26.3 0.7 8.4 4.7 1.5 5.5 6.1 6.8 2.2 8.6 9.2 11.0 13.8 13.5 3.0 3.3 4.3 9.1 5.9 9.0 2.5 16.8 12.9 3.8 7.0 27.5 5.3 17.4 0.6 7.4 3.5 3.5 2.5 8.3 1.4 34.8 23.4 22.1 13.1 9.7 6.9 12.4 7.4 3.6 49.5 11.1 12.0 4.3 5.5 2.2 3.1 10.1 9.9 37.5 10.2 7.2 20.4 98.4 9.3 56.2 0.4 4.1 0.3 0.8 3.5 1.0 11.5 1.5 5.8 2.0 85.4 4.7 2.8 1.7 4.8 9.9 24.9 49.9 42.7 33.7 22.2 30.7 58.7 43.9 53.4 33.3 43.1 75.6 4.5 9.6 5.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 8.8 5.8 0.0 0.0 3.7 3.7 0.0 3.8 1.4 0.0 39.2 11.6 0.0 3.4 3.7 3.7 0.0 0.0 0.0 7.0 0.8 2.9 0.0 4.5 3.8 6.4 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 3.1 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.1 0.0 0.0 12.0 2.2 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 2.6 0.8 5.0 0.0 0.0 MIPEP MIP ENSG00000027001 "Mitochondrial intermediate peptidase" Q99797 13 23730189-23889400 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 108.0;Oligodendrocytes: 62.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 64.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030676, HPA031669, HPA031670" Approved Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA030676: AB_10598907, HPA031669: AB_10600986, HPA031670: AB_10602198" "unprognostic (2.05e-1)" "unprognostic (3.17e-2)" "unprognostic (3.75e-3)" "unprognostic (3.72e-2)" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.21e-1)" "unprognostic (4.69e-2)" "unprognostic (1.12e-1)" "unprognostic (7.54e-2)" "unprognostic (4.76e-1)" "prognostic favorable (7.66e-12)" "unprognostic (1.62e-2)" "unprognostic (4.95e-2)" "unprognostic (2.79e-1)" "unprognostic (6.90e-3)" 6.3 9.6 3.7 6.2 4.3 5.3 11.1 3.2 5.0 7.5 13.4 12.9 8.8 7.2 12.4 11.5 17.3 7.7 18.4 14.4 4.0 25.4 12.0 7.1 5.1 4.0 5.0 5.4 8.2 14.6 5.4 4.7 4.6 10.9 13.1 6.1 9.7 8.7 13.9 21.4 7.6 7.8 4.0 4.3 8.6 9.8 3.7 6.0 11.1 16.9 7.8 7.7 6.4 4.9 14.6 16.1 7.8 18.4 17.4 23.4 16.6 10.3 16.0 15.1 12.7 21.7 28.1 17.0 10.2 8.4 13.3 35.8 18.1 21.6 18.8 9.9 11.5 7.4 7.0 18.8 14.3 17.5 3.9 11.6 26.4 15.7 13.9 12.7 19.2 12.7 14.5 2.7 24.0 10.8 12.6 9.8 10.8 64.8 16.1 13.8 21.0 14.8 33.7 9.6 18.2 6.1 11.0 17.8 21.8 9.8 18.3 9.7 10.7 9.2 7.6 15.3 11.2 2.6 4.0 9.1 15.9 8.8 11.7 0.0 3.0 1.3 7.4 3.7 9.3 8.7 7.1 6.8 6.5 7.2 6.7 6.7 0.0 10.3 12.0 5.5 5.2 4.0 3.7 4.3 3.2 5.0 14.4 4.0 4.0 5.0 4.6 4.0 3.7 4.9 2.5 16.0 8.6 18.9 5.9 39.9 7.7 13.8 6.2 3.6 6.2 5.8 108.0 11.5 12.6 9.2 6.2 9.8 2.4 8.2 29.4 23.4 8.2 26.0 8.5 5.4 6.0 4.6 43.8 10.6 9.3 8.0 7.1 8.5 2.5 4.2 3.6 5.9 9.7 15.2 47.5 7.1 14.2 3.5 5.0 7.4 6.8 4.3 5.4 12.2 3.4 5.5 5.2 18.1 62.8 8.6 7.0 8.6 4.9 7.5 6.6 25.6 46.3 11.4 0.0 7.3 5.7 9.7 19.0 10.1 42.3 5.1 4.0 8.9 13.6 5.6 MMAA cblA ENSG00000151611 "Metabolism of cobalamin associated A" Q8IVH4 4 145599042-145660033 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Chaperone, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 24.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037361, HPA058187" Supported Supported Cytosol No No "Cluster 27: Non-specific - Gene expression" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA037361: AB_10672107, HPA058187: " "unprognostic (1.20e-1)" "unprognostic (5.07e-2)" "prognostic favorable (3.38e-4)" "unprognostic (1.97e-3)" "unprognostic (1.44e-1)" "unprognostic (4.83e-3)" "unprognostic (1.31e-3)" "unprognostic (3.98e-1)" "unprognostic (7.03e-2)" "unprognostic (7.26e-2)" "unprognostic (3.19e-3)" "unprognostic (1.46e-1)" "prognostic favorable (2.23e-5)" "unprognostic (3.40e-2)" "unprognostic (1.45e-1)" "unprognostic (1.14e-1)" "prognostic favorable (3.21e-4)" 4.1 3.2 1.4 3.0 1.9 1.7 4.2 2.7 2.3 3.0 1.3 5.8 7.4 2.4 4.0 4.1 2.7 3.8 3.3 1.5 1.4 7.3 24.5 3.7 3.1 1.3 1.5 2.3 2.0 4.2 0.7 2.8 1.3 2.3 5.3 1.9 3.5 2.8 4.7 3.8 6.2 2.6 1.2 3.5 3.6 4.5 1.3 5.2 3.1 6.0 3.7 4.7 0.8 1.6 2.5 1.4 4.0 2.1 8.4 9.8 1.1 7.1 4.0 2.3 1.4 1.7 4.3 12.1 2.1 4.4 1.1 2.2 2.0 4.4 1.7 7.5 0.8 4.0 1.3 1.5 6.5 5.6 3.3 5.5 6.1 2.6 5.8 3.7 7.2 8.1 1.1 4.6 5.1 3.4 7.2 1.4 1.5 6.2 2.7 3.7 2.2 1.4 13.3 1.3 1.9 1.4 3.5 6.0 3.3 2.4 3.9 1.5 7.0 2.8 1.4 5.0 1.6 2.2 2.0 3.3 4.4 5.5 2.8 3.9 3.1 3.0 4.5 6.1 4.0 3.1 5.3 4.6 3.2 2.6 4.0 5.3 0.5 4.8 7.4 3.3 5.2 2.3 1.4 1.9 2.7 2.3 1.5 1.4 1.3 1.5 1.3 1.2 1.3 1.6 3.6 12.8 5.6 5.5 3.6 2.9 10.4 7.7 5.7 3.4 3.0 2.4 7.6 14.3 13.0 11.0 2.1 7.9 6.5 7.7 15.6 11.1 10.5 5.0 4.5 4.1 2.4 1.7 5.7 12.5 2.8 4.8 7.1 5.7 8.2 3.4 7.9 31.8 4.9 0.0 5.7 6.5 8.2 4.1 1.6 6.3 4.7 3.6 1.8 3.7 5.6 2.3 9.2 8.0 7.4 8.4 7.3 3.0 2.8 6.5 10.9 21.1 6.8 1.6 0.0 4.2 3.8 8.7 5.2 4.4 1.1 7.7 4.5 5.7 6.7 12.2 MMADHC "C2orf25, cblD, CL25022" ENSG00000168288 "Metabolism of cobalamin associated D" Q9H3L0 2 149569637-149587778 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037531, HPA037532" Supported NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA037531: AB_10671628, HPA037532: AB_2675526" "unprognostic (5.67e-2)" "unprognostic (8.86e-2)" "unprognostic (1.98e-2)" "unprognostic (1.80e-3)" "unprognostic (1.15e-1)" "unprognostic (2.07e-3)" "unprognostic (8.17e-2)" "unprognostic (4.18e-3)" "unprognostic (1.05e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.73e-4)" "unprognostic (3.14e-2)" "unprognostic (5.64e-2)" "unprognostic (2.14e-1)" "unprognostic (1.96e-1)" "unprognostic (3.54e-1)" "unprognostic (1.16e-1)" 64.9 62.5 32.0 53.0 33.3 144.3 96.7 36.1 40.7 71.0 38.9 78.0 66.4 68.3 55.5 88.7 64.6 58.0 113.9 32.9 34.7 97.1 195.1 53.7 75.3 33.8 33.0 67.6 86.9 91.7 38.6 76.5 34.5 76.7 90.1 37.8 86.0 69.5 201.2 85.5 62.1 79.0 35.5 56.2 68.7 70.4 34.3 88.8 65.8 187.8 93.3 85.7 57.6 36.9 124.8 90.8 113.9 282.4 134.4 222.9 173.9 198.7 262.0 204.8 175.1 174.8 135.3 199.0 109.5 214.0 121.1 156.7 160.8 203.2 257.5 134.9 130.4 159.0 111.0 193.4 218.0 241.0 145.6 180.2 204.4 265.7 273.1 190.3 233.8 130.5 216.2 205.3 245.0 134.7 106.3 151.8 163.6 168.5 182.9 129.2 130.5 170.9 219.4 209.6 144.0 80.4 148.4 135.4 196.7 122.7 139.6 133.4 160.1 162.5 153.4 120.8 155.2 130.1 177.2 213.9 159.5 143.9 220.6 183.5 77.1 129.6 75.0 87.4 88.3 103.2 94.0 83.4 113.8 85.2 98.4 81.5 150.0 119.7 106.0 96.3 124.0 119.8 32.0 33.3 36.1 40.7 32.9 34.7 33.8 33.0 34.5 35.5 34.3 36.9 50.3 48.1 57.4 12.1 78.3 131.7 183.9 262.2 106.4 24.7 64.2 70.0 162.8 80.1 147.3 49.7 12.5 150.4 63.2 76.7 201.5 148.8 179.9 68.6 48.0 77.5 97.4 156.5 14.7 186.0 178.7 86.5 82.6 53.5 66.0 47.5 79.9 135.6 129.5 20.2 21.1 128.2 166.8 101.9 69.3 46.4 66.5 67.2 78.2 11.2 93.8 55.9 87.6 18.1 19.1 154.5 80.1 78.2 125.8 177.3 95.9 215.0 143.2 19.2 98.6 74.3 89.7 223.0 53.6 114.2 141.5 245.0 68.1 90.3 87.1 237.0 MMP2 "CLG4, CLG4A, TBE-1" ENSG00000087245 "Matrix metallopeptidase 2" P08253 16 55389700-55506691 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 1062.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 222.4;Extravillous trophoblasts: 467.9;Fibroblasts: 815.9;Leydig cells: 340.2;Peritubular cells: 419.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 5619.3;ASC TERT1: 1623.2;hTERT-RPE1: 6400.4;U-87 MG: 1812.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001939, CAB002788" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 1600000000 220000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB002788: , HPA001939: AB_1079395" "unprognostic (7.26e-2)" "unprognostic (1.36e-3)" "unprognostic (1.66e-1)" "unprognostic (2.14e-3)" "unprognostic (5.03e-2)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (9.36e-3)" "unprognostic (4.81e-3)" "unprognostic (3.79e-2)" "unprognostic (4.59e-3)" "unprognostic (6.12e-2)" "unprognostic (1.28e-3)" "unprognostic (1.59e-2)" "unprognostic (8.00e-2)" "unprognostic (8.98e-2)" "unprognostic (4.63e-2)" 518.9 68.3 3.9 135.1 4.0 1.2 328.9 4.9 7.8 514.1 9.4 173.8 57.4 453.6 192.6 121.5 190.6 1062.9 212.8 3.6 5.3 43.7 15.6 279.7 28.1 7.6 4.9 271.1 42.8 13.8 14.7 225.0 5.4 116.8 171.3 11.4 124.1 137.5 60.8 455.6 177.3 468.5 6.7 58.3 134.0 49.6 8.6 19.8 113.5 66.1 30.3 660.8 238.1 10.0 6.5 3.9 192.0 2.4 5619.3 1623.2 312.7 501.4 1146.1 99.4 79.0 0.2 2.1 0.5 391.7 891.0 37.0 54.2 1.2 4.6 57.0 0.7 0.9 0.7 12.9 3.0 530.6 0.4 14.8 1396.8 1.7 512.4 4.4 6400.4 651.1 0.5 0.7 2.4 334.7 0.0 0.4 8.2 152.4 0.5 1.6 0.4 46.1 0.9 16.1 7.6 3.2 345.0 93.3 0.8 2.1 849.0 1.6 36.0 924.6 1546.0 144.9 300.5 66.9 1.0 0.6 2.2 1812.3 28.3 289.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.0 4.9 7.8 3.6 5.3 7.6 4.9 5.4 6.7 8.6 10.0 38.4 0.0 0.5 0.0 0.0 122.1 14.1 48.8 9.1 30.5 3.1 16.8 4.4 0.0 3.1 11.0 0.0 5.6 0.5 0.1 0.0 2.5 12.5 7.7 222.4 46.9 28.2 0.0 0.0 0.4 467.9 815.9 12.2 5.4 0.0 0.0 13.2 0.1 28.2 1.7 0.2 0.1 2.0 1.6 180.7 40.2 340.2 11.8 128.1 27.2 0.0 7.7 0.0 5.0 0.0 9.3 0.0 419.0 2.8 5.6 0.0 0.2 1.1 2.5 13.1 80.0 65.3 1.2 2.8 6.6 102.3 17.2 10.3 35.2 0.0 4.4 MMP7 "MPSL1, PUMP-1" ENSG00000137673 "Matrix metallopeptidase 7" P09237 11 102520508-102530750 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 509.9;salivary gland: 267.9;urinary bladder: 211.2" "Cell type enriched" "Detected in many" 8 "Ductal cells: 8176.2" "Cancer enhanced" "Detected in all" "pancreatic cancer: 352.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 145.9;CAPAN-2: 815.9;EFO-21: 189.8;RPTEC TERT1: 350.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025869, HPA051358" Supported Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" NA NA 2810000 35000 "Cluster 5: Breast - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Vesicles" "CAB025869: , HPA051358: AB_2681452" "unprognostic (1.06e-3)" "unprognostic (9.51e-2)" "unprognostic (4.15e-2)" "unprognostic (1.38e-1)" "unprognostic (7.70e-3)" "unprognostic (7.28e-2)" "prognostic unfavorable (2.53e-4)" "prognostic unfavorable (3.38e-4)" "unprognostic (3.96e-2)" "unprognostic (5.63e-2)" "unprognostic (6.59e-3)" "unprognostic (1.51e-1)" "unprognostic (6.36e-3)" "unprognostic (1.42e-2)" "unprognostic (5.54e-2)" "unprognostic (1.48e-1)" "unprognostic (1.46e-1)" 3.8 0.1 0.0 2.0 0.0 0.3 168.7 0.0 0.3 13.3 0.0 1.6 0.6 97.4 27.9 21.3 91.2 509.9 0.2 0.0 0.0 140.2 3.4 31.6 1.9 0.0 0.0 0.7 85.2 0.0 0.3 0.8 0.0 54.0 1.0 0.0 267.9 34.9 0.1 32.4 0.6 4.8 0.0 0.2 7.3 0.6 0.4 3.3 0.4 0.0 29.3 211.2 1.7 0.0 0.2 145.9 0.0 0.4 0.0 0.0 0.2 0.0 2.1 0.1 0.1 1.9 815.9 0.0 189.8 0.0 0.0 1.1 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.6 1.0 0.1 0.2 0.7 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.5 11.8 0.0 0.0 0.0 0.0 350.1 1.0 0.0 0.0 0.0 0.0 0.0 3.9 0.3 0.1 0.0 0.7 3.0 0.0 1.6 0.1 0.6 0.4 1.0 5.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 86.6 43.3 0.0 1.5 1.0 382.2 135.4 1.2 0.0 124.2 93.7 0.7 100.1 401.2 1017.0 0.0 0.7 2.9 1.2 0.0 8176.2 6.1 62.1 3.3 8.8 0.0 0.0 0.0 209.4 0.3 3.4 0.0 124.6 2.5 0.0 0.0 0.0 98.0 0.0 0.0 0.0 38.7 0.6 0.3 10.3 11.8 12.6 0.0 0.0 65.2 0.0 0.0 0.0 0.0 850.9 0.0 0.0 0.1 603.3 0.0 33.9 72.6 0.0 0.0 0.0 31.4 0.1 0.2 17.0 2.4 0.8 3.6 0.0 2.3 840.8 MMRN1 "ECM, EMILIN4, GPIa*, MMRN" ENSG00000138722 "Multimerin 1" Q13201 4 89879532-89954629 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Endothelial cells: 158.0;Hepatic stellate cells: 146.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 9 "NK-cell: 6.3;plasmacytoid DC: 2.2" "Group enriched" "Detected in many" 9 "dendritic cells: 2.2;NK-cells: 6.3" "Cell line enriched" "Detected in some" 13 "HUVEC TERT2: 1242.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA035769 Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 200000000 "Cluster 48: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA035769: AB_10696511" "unprognostic (1.15e-1)" "unprognostic (1.81e-2)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.11e-1)" "unprognostic (7.05e-3)" "unprognostic (1.62e-3)" "unprognostic (1.91e-1)" "unprognostic (1.88e-1)" "unprognostic (2.12e-1)" "unprognostic (9.71e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.77e-4)" "prognostic unfavorable (5.46e-4)" "unprognostic (2.14e-1)" "unprognostic (1.36e-1)" "unprognostic (2.23e-2)" 22.6 3.8 0.8 10.9 0.8 1.8 27.3 0.8 1.1 28.5 1.4 9.9 5.4 15.0 2.8 14.5 23.1 21.1 3.6 0.6 0.9 1.1 8.7 16.1 14.0 1.4 1.4 4.9 3.4 0.5 0.7 40.1 1.2 3.8 14.9 0.5 2.7 4.6 1.1 8.2 13.5 16.8 1.1 0.6 5.2 12.7 1.5 3.7 23.1 6.6 7.6 19.6 9.8 1.1 0.0 0.0 94.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 1242.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 43.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 6.3 0.0 2.2 0.2 1.2 0.8 0.8 0.8 1.1 0.6 0.9 1.4 1.4 1.2 1.1 1.5 1.1 15.4 0.0 12.0 0.3 2.3 4.2 0.1 0.0 0.0 0.0 0.7 0.1 2.2 0.0 0.6 0.0 0.0 0.0 3.9 0.0 1.9 0.0 17.7 0.3 0.7 158.0 0.0 25.9 0.2 0.0 0.0 1.9 0.0 0.4 2.5 0.1 146.3 2.4 0.6 0.0 0.1 0.0 0.0 5.7 5.9 7.7 0.3 9.1 1.8 21.5 0.7 0.8 2.1 0.0 0.4 0.0 0.0 0.0 5.0 0.4 0.0 0.0 1.5 0.4 0.0 0.3 0.9 15.4 0.0 0.8 4.5 0.0 1.6 0.0 0.0 0.1 MMRN2 "EMILIN3, EndoGlyx-1, FLJ13465" ENSG00000173269 "Multimerin 2" Q9H8L6 10 86935540-86969481 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 11 "Adipocytes: 229.3;Endothelial cells: 127.1;Hepatic stellate cells: 182.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 89.2;HUVEC TERT2: 196.6;TIME: 237.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020741 Approved Vesicles "Secreted to extracellular matrix" NA NA 84000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA020741: AB_1848154" "unprognostic (4.17e-1)" "unprognostic (7.87e-2)" "unprognostic (6.67e-3)" "unprognostic (3.30e-1)" "unprognostic (1.73e-1)" "unprognostic (2.08e-2)" "unprognostic (1.75e-3)" "unprognostic (1.43e-1)" "unprognostic (2.09e-2)" "unprognostic (3.11e-2)" "unprognostic (1.81e-2)" "unprognostic (1.34e-1)" "unprognostic (6.17e-3)" "unprognostic (1.54e-3)" "unprognostic (1.25e-1)" "unprognostic (6.44e-2)" "unprognostic (1.66e-1)" 63.2 13.9 14.0 10.1 12.7 1.5 54.5 11.5 12.5 20.6 11.0 14.2 10.5 28.1 13.8 16.9 22.7 16.6 38.8 11.4 11.9 22.0 8.6 32.1 9.7 13.6 12.4 23.1 10.5 10.6 7.6 73.8 13.7 14.1 8.9 3.0 26.6 28.7 26.8 38.9 13.8 27.3 13.2 34.6 11.9 15.3 15.8 6.5 25.8 32.5 13.3 32.3 19.1 12.0 11.4 2.9 0.4 0.2 1.2 6.3 7.1 4.1 11.1 4.8 6.8 6.4 89.2 0.1 39.5 7.6 11.6 21.9 0.0 5.2 6.4 8.1 0.0 2.3 10.2 0.2 0.9 0.0 4.6 1.5 26.4 5.7 38.6 13.0 196.6 2.4 2.1 35.0 1.8 7.1 0.4 4.4 2.0 0.4 4.9 0.2 0.1 0.1 2.0 17.5 4.8 0.0 3.1 3.7 1.4 0.9 14.9 1.2 237.1 1.9 11.0 1.9 0.1 2.6 4.0 0.1 5.8 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 14.0 12.7 11.5 12.5 11.4 11.9 13.6 12.4 13.7 13.2 15.8 12.0 229.3 0.0 5.8 1.6 0.3 9.4 0.9 0.0 4.6 0.2 1.4 2.0 13.2 5.7 0.7 1.8 0.0 0.7 0.4 0.0 0.0 0.1 1.0 0.3 0.4 127.1 0.0 2.7 0.9 0.0 0.1 8.1 0.0 0.5 0.0 0.2 182.0 4.1 1.7 0.0 1.2 0.0 0.0 6.5 4.4 2.8 2.5 0.7 3.6 15.9 0.0 0.7 0.0 1.0 0.1 0.0 0.0 3.0 0.1 0.6 0.5 0.2 0.0 0.6 6.6 3.9 9.4 1.8 2.3 2.2 7.7 0.3 0.8 3.6 0.2 1.0 MMS19 "CIAO4, hMMS19, MET18, MMS19L" ENSG00000155229 "MMS19 homolog, cytosolic iron-sulfur assembly component" Q96T76 10 97458324-97498794 "Predicted intracellular proteins" "Chromosome partition, DNA damage, DNA repair, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051936, HPA056299" Approved Enhanced Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "HPA051936: AB_2681668, HPA056299: AB_2683091" "unprognostic (8.57e-2)" "unprognostic (2.38e-3)" "unprognostic (9.34e-3)" "unprognostic (1.84e-1)" "unprognostic (2.04e-1)" "unprognostic (1.29e-2)" "prognostic unfavorable (6.88e-4)" "unprognostic (4.40e-1)" "unprognostic (1.99e-2)" "unprognostic (4.90e-2)" "unprognostic (1.17e-1)" "unprognostic (9.06e-3)" "unprognostic (6.79e-2)" "unprognostic (6.49e-2)" "unprognostic (4.06e-1)" "unprognostic (3.51e-2)" "prognostic unfavorable (3.39e-4)" 25.9 23.3 45.1 14.9 47.1 16.4 27.0 45.7 66.4 27.7 45.3 26.1 14.2 24.6 18.3 32.8 24.8 13.1 39.3 47.6 44.0 37.3 24.0 25.1 22.3 44.7 44.2 30.3 30.6 17.1 35.7 20.6 45.2 23.5 17.5 28.8 26.7 15.8 38.0 44.4 28.4 17.8 43.4 33.4 27.9 47.2 45.8 25.8 23.5 29.2 22.7 25.6 30.3 44.9 39.1 36.5 43.3 61.1 41.4 49.9 26.3 30.7 61.6 45.8 53.5 48.9 49.7 59.9 32.5 42.1 30.4 43.5 71.5 82.7 43.1 26.3 54.5 32.0 30.5 51.8 31.3 42.7 29.9 41.5 35.7 40.7 86.3 88.8 78.2 44.7 45.5 32.8 45.1 35.1 40.5 77.3 24.6 39.0 29.8 32.1 33.0 27.1 55.0 27.9 17.8 29.5 17.8 23.4 48.3 53.7 47.9 37.8 45.0 21.1 26.0 14.2 35.6 29.5 35.0 34.6 31.5 62.3 17.3 10.5 6.1 4.6 5.4 6.6 9.3 6.0 7.2 6.8 8.5 5.0 8.7 7.1 1.2 5.7 5.2 6.3 7.2 6.3 45.1 47.1 45.7 66.4 47.6 44.0 44.7 44.2 45.2 43.4 45.8 44.9 9.4 22.4 16.0 21.2 10.0 10.5 6.2 11.3 12.5 10.6 9.2 11.2 18.0 12.8 8.2 5.5 18.8 13.7 13.4 8.7 11.7 11.1 9.6 5.6 12.1 13.0 10.2 11.6 32.8 8.1 18.8 9.9 16.8 9.0 3.8 12.8 15.4 14.4 12.4 10.1 29.7 14.6 4.1 12.6 9.6 7.4 15.5 9.0 14.2 7.5 15.6 6.4 6.2 27.6 38.6 9.7 4.1 11.3 10.7 6.1 9.1 6.7 7.6 22.2 13.1 9.1 8.8 22.2 28.5 12.7 11.5 8.8 9.7 9.7 13.1 4.9 MOCS1 MOCOD ENSG00000124615 "Molybdenum cofactor synthesis 1" Q9NZB8 6 39899578-39934551 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 33.7;Hepatocytes: 36.2;Sertoli cells: 78.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 40.4;JURKAT: 51.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045783, HPA058177, HPA075505" Uncertain Enhanced Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA045783: AB_10960058, HPA058177: AB_2683629, HPA075505: AB_2686751" "unprognostic (1.22e-1)" "prognostic unfavorable (1.07e-5)" "unprognostic (3.26e-2)" "unprognostic (1.44e-1)" "unprognostic (9.03e-2)" "unprognostic (1.99e-1)" "unprognostic (2.61e-2)" "unprognostic (4.85e-2)" "unprognostic (3.14e-2)" "unprognostic (1.08e-1)" "prognostic favorable (6.07e-5)" "unprognostic (5.34e-3)" "unprognostic (1.21e-1)" "unprognostic (3.97e-3)" "unprognostic (2.78e-1)" "unprognostic (2.93e-1)" "unprognostic (6.21e-2)" 33.7 9.5 14.6 3.2 17.9 0.0 26.8 16.8 14.7 8.8 11.2 11.7 16.2 10.0 10.1 6.7 10.3 5.5 22.0 12.7 16.0 20.4 40.3 22.9 4.5 17.4 18.8 9.0 11.9 9.6 5.3 35.6 16.2 5.3 5.6 3.0 6.1 7.5 25.7 7.3 12.7 9.2 15.6 2.6 7.6 3.2 17.3 3.3 16.0 45.0 3.4 10.0 6.6 16.4 0.0 2.1 7.0 11.4 19.3 7.2 15.2 8.7 15.0 12.1 10.0 40.4 0.1 0.0 8.4 7.4 7.0 0.4 8.2 9.8 8.7 0.0 8.6 0.0 0.0 13.7 12.2 0.0 3.1 12.0 3.7 7.9 4.2 7.2 10.1 51.1 8.4 0.7 11.7 5.0 16.0 0.0 7.9 0.1 4.6 0.0 6.3 1.1 7.6 8.2 6.1 8.5 0.0 4.2 7.0 6.3 5.2 1.4 16.2 12.2 9.8 7.7 4.1 0.0 1.7 0.0 1.3 0.0 4.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.5 0.0 0.3 0.0 0.0 0.0 0.2 14.6 17.9 16.8 14.7 12.7 16.0 17.4 18.8 16.2 15.6 17.3 16.4 5.7 6.4 1.5 6.2 0.1 0.6 0.6 0.7 1.2 1.6 9.3 6.5 11.6 8.6 0.3 9.2 12.5 33.7 0.5 3.6 5.9 4.4 0.8 0.9 1.6 3.3 0.0 0.0 3.2 4.1 2.3 4.3 1.1 1.4 1.3 6.3 3.3 36.2 2.9 3.3 2.6 3.5 0.0 2.8 1.0 1.8 3.7 0.4 1.8 2.8 0.0 4.6 0.0 1.0 4.4 1.0 9.1 3.0 1.3 0.2 13.2 17.8 0.0 2.2 78.9 3.9 20.3 1.6 1.9 1.2 1.1 6.2 0.3 0.8 5.5 0.6 MOCS2 "MOCO1, MOCS2A, MOCS2B" ENSG00000164172 "Molybdenum cofactor synthesis 2" "O96007, O96033" 5 53095679-53110063 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 573.2;Proximal tubular cells: 281.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037679, HPA037680" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Nucleoplasm, Nuclear speckles" "HPA037679: AB_2675604, HPA037680: AB_10673635" "unprognostic (3.27e-1)" "unprognostic (3.11e-2)" "unprognostic (2.82e-1)" "unprognostic (8.37e-3)" "unprognostic (2.12e-1)" "unprognostic (3.48e-2)" "unprognostic (1.60e-2)" "unprognostic (1.33e-1)" "unprognostic (6.66e-2)" "unprognostic (7.59e-2)" "unprognostic (2.41e-3)" "unprognostic (1.85e-1)" "prognostic favorable (3.68e-6)" "unprognostic (1.04e-1)" "unprognostic (1.04e-2)" "unprognostic (2.04e-1)" "unprognostic (5.86e-2)" 48.7 79.4 79.1 24.9 84.9 9.1 42.1 80.3 107.6 34.7 74.4 41.9 40.8 30.0 45.9 35.2 26.5 31.3 87.0 84.3 86.3 114.8 126.2 28.2 26.1 79.2 80.5 43.5 42.4 89.6 30.5 35.9 82.4 36.8 32.3 59.3 48.9 44.9 109.3 16.6 40.2 34.4 85.6 23.6 37.2 26.0 88.0 28.3 55.4 111.8 25.2 30.8 24.6 87.4 79.4 62.7 42.9 109.9 85.0 83.2 51.6 99.5 91.9 74.4 89.8 79.7 56.5 76.7 143.5 69.9 127.1 45.0 91.7 96.7 117.2 19.6 84.8 61.7 58.2 75.9 94.4 65.0 43.0 65.1 41.7 91.7 83.5 81.0 85.1 101.4 58.7 44.2 129.5 115.5 72.7 31.8 37.0 34.2 130.1 36.0 93.0 67.0 144.1 56.6 29.4 33.7 69.4 57.3 72.9 56.9 107.2 15.4 55.6 76.9 81.0 69.1 120.5 49.4 84.8 91.5 106.7 16.8 125.1 14.5 21.8 15.6 36.9 26.9 46.2 37.5 42.7 42.8 29.8 40.5 55.3 49.2 3.8 43.5 25.4 27.8 44.9 28.9 79.1 84.9 80.3 107.6 84.3 86.3 79.2 80.5 82.4 85.6 88.0 87.4 51.7 54.5 29.7 14.4 23.5 13.4 40.1 48.5 19.9 30.2 55.7 50.5 122.9 62.9 37.9 69.9 27.1 95.4 19.4 18.2 573.2 43.7 7.3 22.6 29.0 37.6 26.4 18.7 19.1 43.7 37.3 55.7 19.9 26.8 10.1 38.8 26.0 132.6 41.3 6.7 18.4 22.7 44.7 31.2 20.1 14.6 50.7 28.7 23.2 6.5 12.2 67.5 29.9 4.5 11.9 22.1 18.2 68.8 26.7 34.5 65.7 281.7 32.9 21.7 32.9 73.8 49.4 46.7 62.9 37.5 15.6 32.3 25.8 64.2 30.9 34.5 MPC1 "BRP44L, CGI-129, dJ68L15.3, SLC54A1" ENSG00000060762 "Mitochondrial pyruvate carrier 1" Q9Y5U8 6 166364919-166383013 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 739.7;tongue: 559.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 950.0;Distal tubular cells: 1721.8;Proximal tubular cells: 573.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045119, HPA055790" Enhanced Enhanced Mitochondria NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA045119: AB_10960421, HPA055790: AB_2682923" "unprognostic (3.30e-2)" "prognostic favorable (1.45e-4)" "unprognostic (5.24e-3)" "unprognostic (1.68e-1)" "unprognostic (3.17e-2)" "unprognostic (2.85e-2)" "unprognostic (7.61e-2)" "prognostic favorable (1.29e-4)" "unprognostic (3.27e-1)" "unprognostic (1.19e-1)" "unprognostic (1.11e-3)" "unprognostic (5.64e-2)" "prognostic favorable (4.79e-11)" "unprognostic (4.13e-2)" "unprognostic (1.03e-1)" "unprognostic (7.48e-2)" "unprognostic (8.45e-2)" 61.7 39.6 105.9 33.4 119.5 57.0 52.8 129.7 153.1 52.4 108.0 97.7 84.8 35.7 44.8 71.5 34.7 41.7 739.7 101.2 127.8 259.9 411.2 44.6 44.3 119.2 123.9 43.4 66.0 141.8 38.1 23.7 119.5 43.5 89.9 57.3 87.7 42.3 319.4 40.9 63.8 38.5 117.1 35.0 96.1 22.2 121.5 48.6 82.9 559.2 44.2 47.4 34.9 132.4 25.6 7.5 31.3 107.7 88.4 49.8 45.2 29.1 47.1 45.1 43.9 38.8 17.9 53.6 50.9 45.4 36.1 24.5 47.0 36.7 31.9 36.1 79.0 27.5 35.4 132.6 36.6 104.9 34.1 40.0 51.0 36.8 26.7 13.7 36.9 80.8 94.2 84.1 28.6 40.5 73.1 193.7 16.1 148.0 35.5 39.1 51.7 134.9 85.4 20.5 96.7 85.7 33.6 145.8 34.0 25.9 34.5 154.3 25.3 25.7 26.8 91.6 30.0 55.8 42.2 46.3 23.5 127.0 42.1 60.7 60.0 90.1 41.7 98.3 39.4 33.1 48.5 45.1 72.2 25.4 44.7 43.3 54.6 40.5 128.5 43.0 69.1 49.8 105.9 119.5 129.7 153.1 101.2 127.8 119.2 123.9 119.5 117.1 121.5 132.4 56.1 118.6 48.0 64.6 51.7 45.6 44.2 83.6 29.0 61.1 74.2 79.1 950.0 187.3 67.6 106.7 10.4 22.0 54.2 219.1 1721.8 89.3 66.8 73.7 50.7 51.7 37.2 72.6 49.0 140.3 78.3 74.1 63.7 93.2 71.0 28.0 47.5 391.0 121.4 48.8 74.7 122.1 166.8 89.6 81.7 10.2 66.5 80.3 129.9 20.6 104.7 199.9 58.7 32.2 108.0 65.2 125.0 89.9 114.5 32.0 162.0 573.6 46.3 66.7 92.1 76.9 80.4 163.2 79.6 67.3 55.8 24.4 58.4 39.9 146.7 53.6 MPC2 "BRP44, DKFZP564B167, SLC54A2" ENSG00000143158 "Mitochondrial pyruvate carrier 2" O95563 1 167916675-167937072 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 2288.1;Late spermatids: 5134.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056091 Uncertain NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 25: Spermatids - Spermatogenesis" "HPA056091: AB_2683035" "unprognostic (3.25e-1)" "unprognostic (6.82e-2)" "unprognostic (8.79e-3)" "unprognostic (4.15e-2)" "unprognostic (3.47e-1)" "unprognostic (1.02e-1)" "unprognostic (6.01e-2)" "unprognostic (1.53e-1)" "unprognostic (7.93e-2)" "unprognostic (3.36e-3)" "unprognostic (1.44e-3)" "unprognostic (1.08e-2)" "unprognostic (9.13e-2)" "unprognostic (2.39e-1)" "unprognostic (6.95e-2)" "unprognostic (5.43e-2)" "unprognostic (1.67e-1)" 53.6 89.9 32.3 15.8 37.1 63.3 50.7 34.2 39.0 34.3 35.0 80.3 47.8 30.6 15.8 38.8 34.5 19.6 174.0 36.8 35.6 148.1 266.6 35.1 14.0 31.8 33.4 35.3 52.4 35.6 73.5 13.8 31.6 89.3 33.7 28.4 55.3 16.0 162.1 42.5 65.8 14.8 31.5 28.9 140.4 240.4 34.9 20.1 32.3 66.3 15.0 43.0 35.4 34.4 40.7 43.2 14.6 32.3 31.5 26.2 4.1 70.2 26.9 23.7 27.2 92.3 19.6 75.0 49.4 29.1 21.4 31.4 17.0 28.1 20.3 98.3 34.5 33.2 34.1 60.7 22.4 38.1 21.9 19.6 23.6 41.8 21.8 20.0 20.3 52.5 39.6 34.9 38.7 18.1 52.4 31.4 26.2 73.7 45.2 27.8 31.3 54.7 155.0 30.5 25.8 28.4 41.6 39.1 34.3 29.2 73.9 38.9 30.4 27.8 24.8 45.3 29.9 61.2 65.9 74.5 73.5 28.6 14.6 95.0 33.1 92.5 44.1 30.5 45.7 50.2 51.6 45.8 58.7 41.3 48.6 46.7 61.4 55.6 38.5 40.2 81.3 84.2 32.3 37.1 34.2 39.0 36.8 35.6 31.8 33.4 31.6 31.5 34.9 34.4 81.6 35.3 43.7 14.4 75.0 126.1 157.7 213.8 52.9 54.5 167.2 166.9 428.0 513.3 119.2 130.6 22.9 468.6 78.2 267.5 1025.2 206.1 2288.1 153.3 38.5 75.0 331.5 388.3 23.5 145.5 55.3 119.3 112.1 98.3 88.2 332.1 55.3 679.5 159.6 45.4 19.9 326.4 146.5 77.1 113.3 5134.8 106.2 93.9 120.9 15.9 272.9 123.8 76.2 13.0 16.8 100.5 237.2 112.8 84.7 245.6 516.2 974.3 175.3 69.7 65.7 90.3 147.1 788.0 170.5 75.3 114.4 343.1 94.9 705.0 415.5 173.9 MPEG1 MPG1 ENSG00000197629 "Macrophage expressed 1" Q2M385 11 59208510-59212927 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 207.4" "Group enriched" "Detected in some" 4 "dendritic cells: 156.0;Kupffer cells: 409.8;Macrophages: 174.6;monocytes: 218.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 290.5;intermediate monocyte: 209.9;myeloid DC: 144.7;non-classical monocyte: 245.2;plasmacytoid DC: 204.9" "Group enriched" "Detected in many" 6 "dendritic cells: 204.9;monocytes: 290.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA046801 Approved "Secreted to blood" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA046801: AB_2679814" "unprognostic (1.24e-1)" "unprognostic (2.17e-3)" "unprognostic (1.05e-2)" "unprognostic (2.00e-2)" "unprognostic (3.38e-2)" "unprognostic (2.79e-3)" "unprognostic (7.82e-2)" "unprognostic (1.41e-2)" "unprognostic (6.23e-2)" "unprognostic (2.76e-1)" "unprognostic (5.48e-2)" "unprognostic (3.51e-1)" "unprognostic (1.48e-1)" "unprognostic (9.38e-2)" "unprognostic (2.48e-2)" "unprognostic (1.76e-1)" "unprognostic (5.86e-2)" 29.2 15.8 1.5 112.4 1.6 21.3 13.5 1.7 2.4 11.6 3.2 32.9 40.9 10.9 3.7 12.6 6.9 36.2 10.3 1.4 2.1 6.0 41.1 35.4 96.3 3.3 1.9 4.9 4.6 4.6 1.6 35.8 2.5 8.0 43.4 0.3 7.3 9.3 3.9 7.1 52.8 28.2 2.9 207.4 19.2 4.5 4.0 42.8 5.9 8.3 75.2 42.7 2.1 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 290.5 8.4 0.5 209.9 0.5 12.6 0.3 0.2 144.7 14.0 0.2 0.1 38.5 1.2 245.2 204.9 0.6 214.5 1.5 1.6 1.7 2.4 1.4 2.1 3.3 1.9 2.5 2.9 4.0 4.0 0.7 0.0 7.9 0.0 33.8 1.1 0.0 0.0 1.2 0.0 0.3 0.9 1.7 1.5 0.6 0.0 0.0 0.3 156.0 0.1 0.0 0.0 0.2 0.0 0.1 1.7 0.0 4.4 0.0 0.0 0.6 0.8 0.5 0.1 2.5 0.0 4.6 3.7 52.4 0.0 0.0 0.0 0.0 409.8 48.0 0.6 0.0 174.6 1.8 10.3 218.2 0.2 7.2 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.7 0.7 0.1 6.6 0.7 0.4 0.0 0.0 0.3 1.6 0.3 2.7 0.0 0.0 0.1 MPLKIP "C7orf11, ORF20, TTDN1" ENSG00000168303 "M-phase specific PLK1 interacting protein" Q8TAP9 7 40126027-40134622 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058457, HPA065463" Uncertain Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Golgi apparatus, Vesicles" "HPA058457: AB_2683724, HPA065463: AB_2685493" "unprognostic (5.59e-2)" "unprognostic (1.74e-1)" "unprognostic (9.40e-2)" "unprognostic (2.39e-2)" "unprognostic (5.55e-2)" "unprognostic (1.34e-3)" "unprognostic (2.73e-1)" "unprognostic (3.40e-2)" "unprognostic (3.94e-2)" "unprognostic (1.65e-1)" "unprognostic (3.16e-3)" "unprognostic (8.89e-2)" "unprognostic (1.61e-2)" "unprognostic (8.44e-2)" "unprognostic (2.91e-2)" "unprognostic (1.91e-2)" "unprognostic (6.08e-2)" 2.9 3.8 2.6 2.0 2.6 2.4 2.8 4.7 3.0 2.8 3.0 2.8 2.2 2.6 2.0 3.1 2.5 1.2 2.1 2.6 2.3 4.2 8.0 2.1 2.6 2.4 2.3 2.8 2.9 2.5 3.0 1.8 2.6 2.5 1.8 3.1 2.7 1.5 2.4 3.0 2.6 1.1 2.0 3.1 2.4 2.3 2.5 3.3 3.0 1.4 2.0 2.5 2.7 4.0 8.2 2.5 4.8 6.6 4.3 4.9 4.9 3.1 3.3 4.4 4.3 3.1 4.0 6.8 4.2 3.0 8.7 10.3 3.0 5.3 5.6 5.2 9.2 5.4 3.7 6.9 4.9 6.7 5.2 4.8 6.7 3.4 4.1 4.5 5.1 7.5 13.1 5.5 4.4 4.1 6.8 20.4 6.7 6.7 7.4 9.6 3.3 8.9 5.0 2.1 7.1 8.4 5.0 4.8 7.7 6.2 6.1 9.3 5.5 2.8 7.5 3.6 4.7 8.6 9.6 10.9 4.4 10.5 7.6 20.6 11.2 16.8 8.0 10.8 9.0 16.9 10.1 9.4 11.8 15.3 11.3 9.9 9.2 10.6 10.4 13.1 14.2 13.1 2.6 2.6 4.7 3.0 2.6 2.3 2.4 2.3 2.6 2.0 2.5 4.0 49.8 51.3 34.5 6.5 53.3 110.1 96.2 151.8 58.6 43.5 53.8 66.2 18.0 67.2 79.6 58.8 25.0 110.8 41.3 60.3 117.4 66.6 118.4 73.6 62.3 58.0 48.6 52.2 7.4 54.6 79.7 51.1 35.7 56.6 51.3 63.6 47.2 133.4 69.0 53.8 8.1 63.4 85.5 59.3 62.6 38.6 75.8 50.4 58.7 7.5 74.6 52.9 66.9 12.1 12.5 59.9 97.2 55.3 36.3 76.2 61.6 190.5 91.1 50.1 52.6 57.1 58.4 66.6 53.9 67.1 134.1 95.6 46.8 125.7 82.3 105.7 MPZ "CMT1, CMT1B, CMT2I, CMT2J, HMSNIB, P0" ENSG00000158887 "Myelin protein zero" P25189 1 161304735-161309968 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Charcot-Marie-Tooth disease, Deafness, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 6.6;Skeletal myocytes: 9.3" "Cancer enriched" "Detected in many" 11 "melanoma: 83.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "WM-115: 139.3" "Group enriched" "Detected in some" 4 "olfactory bulb: 2.9;pons and medulla: 1.3" "Region enriched" "Detected in some" 10 "spinal cord: 2142.4" HPA068925 Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 46: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "HPA068925: AB_2732123" "unprognostic (6.77e-2)" "unprognostic (2.98e-1)" "unprognostic (9.27e-2)" "unprognostic (1.46e-1)" "unprognostic (3.35e-2)" "unprognostic (1.78e-1)" "unprognostic (1.49e-2)" "unprognostic (2.36e-1)" "unprognostic (2.95e-1)" "unprognostic (1.33e-1)" "unprognostic (7.88e-3)" "unprognostic (1.51e-1)" "unprognostic (6.62e-8)" "unprognostic (6.75e-2)" "unprognostic (1.24e-1)" "unprognostic (1.66e-1)" "unprognostic (8.32e-2)" 19.1 6.9 2.1 2.1 3.0 1.1 12.6 2.5 2.7 8.3 1.4 22.3 1.6 2.0 2.0 4.4 5.3 2.4 15.2 1.9 3.9 6.3 5.4 2.9 1.1 3.0 2.2 3.1 2.3 0.6 6.2 0.6 9.9 12.2 2.7 1.2 15.8 8.0 5.1 9.1 8.5 0.8 3.3 4.4 7.6 2.4 2.0 1.4 3.7 18.4 0.9 9.5 15.9 2.2 0.4 0.0 0.3 0.1 2.7 1.3 0.3 0.3 0.5 0.1 1.6 0.0 0.1 2.3 1.5 0.4 0.5 0.1 1.8 0.6 0.1 1.1 0.0 1.0 0.4 31.0 1.2 4.7 3.7 4.2 0.0 6.2 0.3 0.0 2.8 1.9 9.9 0.0 4.3 0.0 0.7 7.6 1.4 0.0 0.0 0.3 0.2 1.4 0.3 0.1 2.0 0.3 0.0 0.0 14.0 0.8 0.1 9.5 2.7 0.3 0.4 2.7 0.2 0.9 0.9 1.2 4.8 17.5 139.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 3.0 2.5 2.7 1.9 3.9 3.0 2.2 9.9 3.3 2.0 2.2 1.7 3.2 0.6 1.0 2.1 0.5 3.1 0.4 4.0 2.5 0.4 1.3 0.7 0.0 0.5 3.7 2.1 0.5 1.6 0.1 0.0 0.2 5.5 0.3 0.2 1.5 1.8 1.3 1.7 1.2 0.7 2.5 0.0 0.1 0.0 0.8 1.8 1.0 1.6 1.7 2.2 0.7 2.0 1.9 0.8 1.8 1.5 2.0 3.6 1.0 3.8 0.5 0.0 0.5 1.6 0.1 0.1 0.4 1.4 0.9 0.3 1.0 0.6 1.1 6.6 9.3 3.9 0.4 0.6 1.1 0.4 0.3 1.6 0.4 0.4 2.0 MROH7 "C1orf175, FLJ46354, HEATR8" ENSG00000184313 "Maestro heat like repeat family member 7" Q68CQ1 1 54641754-54710266 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "testis: 55.5" "Group enriched" "Detected in some" 57 "Early spermatids: 179.0;Late spermatids: 546.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA071840 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 25: Spermatids - Spermatogenesis" "HPA071840: AB_2732187" "unprognostic (1.52e-3)" "unprognostic (1.51e-3)" "unprognostic (1.65e-2)" "unprognostic (2.77e-4)" "unprognostic (1.81e-1)" "unprognostic (9.88e-4)" "unprognostic (1.09e-1)" "unprognostic (2.84e-1)" "unprognostic (1.84e-1)" "unprognostic (2.11e-1)" "unprognostic (4.16e-2)" "unprognostic (1.79e-2)" "unprognostic (7.93e-2)" "unprognostic (7.40e-3)" "unprognostic (2.38e-1)" "unprognostic (5.83e-2)" "unprognostic (4.15e-2)" 0.2 0.6 2.2 0.0 2.5 0.7 0.2 2.9 2.8 0.7 7.0 3.1 0.1 1.1 1.0 0.6 1.3 0.2 2.7 2.3 2.4 2.3 1.1 0.4 0.1 2.9 3.1 2.9 0.3 0.5 4.3 0.0 2.6 2.3 0.3 0.5 1.8 0.7 0.7 1.0 1.4 0.1 2.5 0.2 1.7 55.5 3.2 0.0 5.3 0.2 0.0 1.8 0.8 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.5 2.9 2.8 2.3 2.4 2.9 3.1 2.6 2.5 3.2 2.5 0.0 0.0 1.3 0.0 0.2 0.9 0.9 0.1 0.0 1.7 0.3 0.5 4.0 0.0 1.4 0.0 0.0 0.0 0.0 4.0 0.0 0.1 179.0 1.1 0.2 0.3 2.4 0.0 0.0 0.4 0.0 0.2 0.0 1.2 5.1 0.3 0.4 0.3 0.4 0.0 0.0 3.0 0.0 1.0 0.7 546.1 4.4 0.5 0.0 0.0 0.7 2.5 0.0 0.0 0.0 0.1 6.1 4.5 0.0 0.3 5.0 0.2 1.0 0.4 0.0 1.9 0.2 6.3 2.8 0.0 0.4 0.1 0.2 0.5 2.2 1.1 MRPL19 "KIAA0104, MRP-L15, RLX1, RPML15" ENSG00000115364 "Mitochondrial ribosomal protein L19" P49406 2 75646783-75690851 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 167.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046805, HPA056622" Approved Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA046805: AB_2679816, HPA056622: AB_2683195" "unprognostic (9.24e-2)" "unprognostic (3.84e-2)" "prognostic favorable (7.39e-4)" "unprognostic (8.40e-2)" "unprognostic (1.59e-2)" "unprognostic (7.52e-3)" "unprognostic (5.75e-2)" "unprognostic (9.86e-2)" "unprognostic (6.21e-3)" "unprognostic (9.71e-3)" "prognostic unfavorable (1.97e-5)" "unprognostic (2.42e-1)" "unprognostic (3.67e-2)" "unprognostic (1.55e-1)" "unprognostic (3.30e-1)" "unprognostic (1.12e-1)" "unprognostic (1.20e-1)" 31.3 30.1 21.8 18.9 27.4 13.9 28.6 26.5 23.5 29.1 14.8 27.8 23.7 21.7 25.2 25.0 18.1 20.7 35.0 18.8 26.7 56.0 63.7 17.8 20.3 23.4 24.4 17.4 23.6 45.2 12.2 25.7 25.4 21.6 30.9 19.3 24.1 25.1 66.4 23.9 19.9 29.0 26.8 16.9 18.4 16.5 24.9 24.3 36.9 44.8 25.1 24.5 15.1 32.5 100.7 57.5 53.3 48.3 57.0 68.1 75.6 63.4 57.0 78.5 62.2 88.5 40.6 56.5 62.1 69.2 73.8 69.5 83.7 95.8 117.8 63.2 72.4 77.4 44.4 114.3 61.0 82.9 44.5 45.6 72.4 79.7 72.3 49.6 84.1 60.8 86.4 32.3 78.5 61.9 76.1 64.9 69.9 102.9 65.2 94.5 116.5 74.5 134.1 61.9 58.8 50.2 62.2 71.2 72.4 53.3 61.1 32.8 57.0 68.3 75.4 61.2 94.6 33.3 53.8 47.1 53.9 81.0 61.1 17.7 20.2 14.2 22.1 26.8 25.1 26.8 22.7 23.8 29.7 22.7 19.9 24.6 1.4 24.4 24.9 35.0 26.5 17.2 21.8 27.4 26.5 23.5 18.8 26.7 23.4 24.4 25.4 26.8 24.9 32.5 31.8 19.2 29.6 10.7 27.4 29.1 28.6 77.8 21.1 38.3 32.4 29.5 40.2 25.8 49.4 49.7 52.1 90.3 26.3 24.0 125.2 88.7 27.6 42.7 48.4 27.7 27.6 32.8 13.9 61.1 87.3 33.7 36.7 50.3 19.0 35.8 27.1 67.6 47.3 48.8 14.3 36.5 44.7 14.6 17.0 11.2 35.4 23.7 33.8 12.2 35.0 39.6 34.0 15.1 20.0 53.6 27.7 36.5 36.5 36.1 36.5 167.7 32.8 50.9 19.7 31.4 38.1 55.5 17.6 44.3 28.3 57.7 25.3 62.2 50.7 35.6 MRPL37 "MRP-L2, RPML2" ENSG00000116221 "Mitochondrial ribosomal protein L37" Q9BZE1 1 54184041-54225464 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025767, HPA025826, HPA025951" Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "HPA025767: AB_1854105, HPA025826: AB_1854106, HPA025951: AB_1854107" "unprognostic (2.00e-1)" "unprognostic (6.81e-2)" "prognostic favorable (6.99e-4)" "unprognostic (1.71e-3)" "unprognostic (8.24e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (6.45e-5)" "unprognostic (2.49e-2)" "unprognostic (1.56e-1)" "unprognostic (1.64e-1)" "unprognostic (1.92e-2)" "unprognostic (1.84e-1)" "unprognostic (3.07e-1)" "prognostic favorable (9.25e-4)" "unprognostic (2.43e-1)" "unprognostic (2.62e-1)" "unprognostic (7.67e-3)" 44.7 73.8 28.6 32.4 30.6 67.4 41.5 35.5 37.2 36.1 42.7 50.7 51.5 34.7 26.9 65.8 38.2 25.5 86.3 31.5 29.8 55.4 108.1 30.2 41.1 32.5 30.3 41.0 67.7 47.2 20.8 31.5 33.2 33.8 53.5 21.8 41.3 29.8 167.9 56.2 41.0 41.6 27.4 34.6 49.2 31.4 30.8 41.2 28.5 154.2 51.3 37.9 40.5 28.7 168.3 94.9 84.6 114.5 83.4 110.9 150.5 111.2 103.5 194.0 167.7 190.7 75.4 226.1 98.2 125.3 184.8 131.6 168.2 164.6 150.6 111.1 211.7 194.8 186.9 194.8 142.9 233.3 87.1 123.2 138.7 201.8 156.5 108.7 176.1 174.2 219.2 66.1 140.2 123.3 161.7 226.4 173.5 134.4 208.2 175.3 171.7 191.6 110.8 123.4 166.3 77.6 153.8 261.4 214.0 110.6 113.2 260.7 88.5 123.6 112.2 157.7 227.1 83.1 126.0 175.5 161.1 234.2 119.9 53.0 103.4 45.4 67.5 91.8 79.1 120.4 81.9 76.1 120.4 105.1 82.0 72.8 5.6 94.0 88.7 101.5 116.4 126.6 28.6 30.6 35.5 37.2 31.5 29.8 32.5 30.3 33.2 27.4 30.8 28.7 24.0 22.4 18.7 3.9 33.4 34.7 43.8 84.6 45.5 8.9 46.3 57.0 71.3 55.8 43.1 18.4 2.1 118.0 15.5 36.6 80.3 81.2 31.0 25.7 23.2 30.3 33.1 103.3 7.5 96.3 145.8 37.3 41.8 33.1 14.5 40.6 37.5 156.5 87.0 6.7 8.4 53.0 52.9 43.6 25.6 57.5 26.1 30.9 23.2 4.7 53.1 9.2 24.7 4.5 5.4 69.0 41.1 28.6 72.2 54.2 73.8 105.2 29.4 8.7 13.1 28.8 34.3 23.6 50.4 79.6 37.4 73.9 24.5 57.2 86.0 55.2 MRPL45 MGC11321 ENSG00000278845 "Mitochondrial ribosomal protein L45" 17 38297023-38323217 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebral cortex: 8.4" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "AF22: 35.7;Daudi: 80.9;K-562: 57.0;REH: 43.2;RPMI-8226: 34.4;RT4: 33.9;U-266/84: 52.1;U-698: 56.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023373, HPA023385" Enhanced Enhanced Mitochondria NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 32: Non-specific - Translation" Mitochondria "HPA023373: AB_1854114, HPA023385: AB_1854115" "unprognostic (8.56e-3)" "unprognostic (4.09e-2)" "unprognostic (1.11e-2)" "unprognostic (3.08e-1)" "unprognostic (9.50e-2)" "unprognostic (2.22e-3)" "unprognostic (1.11e-2)" "unprognostic (1.60e-1)" "unprognostic (7.21e-2)" "unprognostic (1.37e-2)" "unprognostic (3.65e-1)" "unprognostic (1.35e-1)" "unprognostic (6.01e-3)" "unprognostic (3.07e-1)" "unprognostic (1.00e-1)" "unprognostic (2.40e-1)" "unprognostic (8.13e-2)" 24.0 26.7 1.5 2.2 1.9 1.9 24.1 1.6 8.4 21.1 2.2 24.6 0.0 21.4 0.0 25.3 19.8 4.0 32.1 1.6 1.6 26.0 30.7 15.2 8.0 1.7 1.6 28.3 36.8 9.0 13.1 1.7 1.7 18.0 5.7 1.3 22.4 0.0 61.8 26.5 19.6 0.7 1.5 16.3 30.0 9.5 1.6 2.6 18.2 0.0 6.9 22.1 20.1 1.6 0.0 0.5 35.7 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 26.8 80.9 0.2 0.0 24.2 0.5 0.2 0.0 0.1 0.0 0.3 31.1 0.0 2.1 12.7 0.0 0.2 0.0 0.3 0.1 0.0 0.1 0.0 0.0 57.0 0.0 0.2 0.0 23.1 0.0 0.3 0.1 0.0 43.2 0.2 34.4 0.0 33.9 0.1 0.2 0.2 0.6 0.2 0.1 0.1 0.2 0.5 15.1 0.1 0.0 0.3 23.2 52.1 56.9 0.1 0.0 0.4 0.6 6.7 2.2 5.3 8.2 6.4 7.6 7.7 4.1 11.3 6.8 9.8 6.6 0.2 9.8 2.3 4.8 6.6 6.3 1.5 1.9 1.6 8.4 1.6 1.6 1.7 1.6 1.7 1.5 1.6 1.6 20.4 12.8 12.1 6.8 23.8 30.2 39.3 54.6 42.7 10.9 41.3 37.7 46.5 32.9 23.9 25.8 8.4 69.3 16.3 11.3 60.7 41.5 18.3 21.6 25.6 26.9 16.3 45.9 10.4 37.5 67.7 25.1 24.5 21.1 23.5 31.4 22.5 30.4 42.6 16.8 12.0 27.4 34.6 39.1 21.1 15.0 20.8 22.2 19.6 1.9 43.8 13.0 22.6 7.5 9.2 29.6 15.5 16.6 23.7 28.8 32.0 64.0 21.6 11.1 6.6 28.4 25.2 30.6 18.0 31.9 32.4 71.1 19.3 42.6 41.8 33.3 MRPL46 "C15orf4, LIECG2, P2ECSL" ENSG00000259494 "Mitochondrial ribosomal protein L46" Q9H2W6 15 88459477-88467390 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Proximal tubular cells: 133.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050166, HPA076046" Approved Supported "Nucleoplasm,Cell Junctions,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Cell Junctions" "HPA050166: AB_2681039, HPA076046: " "unprognostic (1.42e-1)" "unprognostic (6.94e-3)" "unprognostic (1.02e-1)" "unprognostic (1.21e-2)" "unprognostic (3.28e-2)" "unprognostic (5.16e-2)" "unprognostic (6.22e-2)" "unprognostic (1.84e-1)" "unprognostic (1.79e-1)" "unprognostic (4.64e-3)" "unprognostic (7.78e-2)" "unprognostic (5.65e-2)" "prognostic favorable (2.09e-6)" "unprognostic (7.73e-2)" "unprognostic (9.18e-2)" "unprognostic (6.96e-3)" "unprognostic (1.63e-1)" 25.1 51.5 20.3 12.9 21.7 11.3 22.7 23.7 25.4 14.6 22.0 24.2 20.0 17.1 18.2 26.4 17.1 13.0 76.1 20.8 23.6 34.7 70.9 12.7 20.9 23.1 22.1 17.2 16.2 24.6 16.2 19.6 23.6 14.9 23.6 16.8 17.1 15.2 73.3 17.9 19.7 18.4 21.7 19.1 24.8 28.1 22.7 18.9 17.2 84.6 20.3 20.7 16.2 22.6 27.8 87.2 27.2 29.8 38.0 28.6 51.5 38.6 35.5 56.9 50.4 108.6 59.3 64.9 38.6 34.9 51.0 65.9 107.4 47.4 44.8 26.3 86.4 53.6 61.5 114.3 24.6 54.2 40.4 32.7 56.6 42.8 28.7 29.0 50.2 63.2 60.7 26.6 42.7 59.6 44.2 68.4 43.5 50.5 52.9 51.9 37.9 49.2 44.5 88.2 42.1 26.5 36.6 57.7 81.8 44.6 64.8 65.7 31.3 44.0 41.9 23.3 56.4 24.2 55.7 53.0 48.5 58.1 34.2 27.1 45.5 33.7 60.0 60.5 69.6 78.8 63.3 58.7 58.7 69.5 69.5 61.6 7.9 62.9 45.0 50.5 68.0 61.5 20.3 21.7 23.7 25.4 20.8 23.6 23.1 22.1 23.6 21.7 22.7 22.6 18.9 0.0 10.3 5.2 21.0 13.8 22.4 59.8 9.6 21.2 17.3 21.3 70.4 37.1 32.3 36.8 27.1 94.3 10.7 20.4 119.3 35.0 67.1 20.0 16.6 18.4 28.3 17.7 4.2 38.0 42.1 19.2 19.9 19.5 22.2 25.8 17.2 105.0 35.6 15.2 5.9 20.6 44.7 13.4 5.5 16.3 14.3 10.8 7.2 3.7 42.1 25.1 20.6 4.5 6.1 31.7 18.4 18.8 17.3 21.9 32.1 133.6 26.2 28.4 26.3 19.5 25.5 55.3 27.4 27.1 23.3 80.7 18.5 66.9 36.1 29.4 MRPS18B "C6orf14, HSPC183, MRPS18-2, PTD017" ENSG00000204568 "Mitochondrial ribosomal protein S18B" Q9Y676 6 30617840-30626395 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043485, HPA050334" Supported Supported "Cell Junctions,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Cell Junctions" "HPA043485: AB_2678506, HPA050334: AB_2681091" "unprognostic (8.18e-3)" "unprognostic (1.14e-1)" "unprognostic (8.96e-2)" "unprognostic (2.51e-2)" "unprognostic (4.20e-2)" "unprognostic (7.40e-2)" "unprognostic (9.45e-2)" "unprognostic (1.32e-1)" "unprognostic (1.89e-1)" "unprognostic (2.98e-2)" "unprognostic (1.76e-1)" "unprognostic (1.40e-2)" "prognostic favorable (3.99e-5)" "unprognostic (1.89e-1)" "unprognostic (1.64e-1)" "unprognostic (5.14e-2)" "unprognostic (5.39e-2)" 37.2 52.0 43.6 27.6 45.7 20.3 61.0 46.8 44.3 41.1 43.2 52.3 49.8 31.3 57.6 39.3 62.5 27.4 108.1 40.5 44.1 77.9 99.8 39.4 43.6 46.0 45.2 63.0 47.0 74.0 29.2 38.4 46.2 32.0 62.3 41.6 58.0 42.4 180.2 45.1 39.4 38.1 45.2 39.3 44.4 22.0 46.1 43.7 54.1 229.0 63.6 33.0 29.4 48.2 112.7 68.3 51.1 73.5 72.9 101.8 92.6 39.8 92.6 122.8 75.5 117.7 51.8 112.6 91.5 61.7 91.3 86.1 115.0 109.9 122.0 68.7 122.9 107.9 45.1 124.2 67.2 105.7 45.4 88.8 139.4 99.5 273.8 82.7 72.4 104.7 171.3 107.7 112.2 83.1 70.6 111.4 40.6 86.1 81.8 91.2 69.8 220.7 114.8 49.5 111.3 38.4 34.7 147.1 163.0 46.0 190.6 58.4 39.6 79.2 80.8 47.3 70.8 89.5 114.1 99.2 38.3 154.6 121.7 79.2 72.4 42.5 77.0 94.4 104.7 153.5 104.3 86.3 79.8 140.3 129.6 103.5 7.2 120.3 101.4 74.3 108.1 108.4 43.6 45.7 46.8 44.3 40.5 44.1 46.0 45.2 46.2 45.2 46.1 48.2 59.4 60.9 56.1 7.2 58.4 36.8 65.9 114.0 58.6 47.4 56.6 73.0 175.5 117.2 75.0 47.8 64.6 121.2 43.7 39.1 193.7 103.8 54.2 37.5 42.8 59.4 31.3 45.4 6.0 92.1 124.9 47.4 39.3 30.8 37.4 53.1 61.8 121.6 81.4 43.7 7.9 59.5 75.3 53.2 30.4 37.4 70.2 39.7 60.5 1.9 80.0 46.9 70.0 4.5 14.4 69.5 49.9 44.8 56.8 53.2 89.6 201.6 60.4 69.4 52.6 50.0 53.0 29.6 57.4 61.7 44.9 96.5 43.9 144.4 85.3 50.1 MSR1 "CD204, SCARA1, SR-A, SR-AI, SR-AII, SR-AIII" ENSG00000038945 "Macrophage scavenger receptor 1" P21757 8 16107878-16567490 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lung: 120.1" "Group enriched" "Detected in many" 5 "Hofbauer cells: 137.3;Kupffer cells: 322.8;Langerhans cells: 86.0;Macrophages: 172.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 16.9" "Lineage enriched" "Detected in many" 5 "monocytes: 16.9" "Group enriched" "Detected in many" 7 "BJ hTERT+: 105.2;REH: 40.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000272, CAB032491" Enhanced NA NA 67000 "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032491: AB_672722, HPA000272: AB_1846269" "unprognostic (8.19e-3)" "unprognostic (4.87e-2)" "unprognostic (1.93e-2)" "unprognostic (2.10e-1)" "unprognostic (9.24e-2)" "unprognostic (1.32e-2)" "unprognostic (5.85e-3)" "unprognostic (2.89e-1)" "unprognostic (9.70e-2)" "unprognostic (1.62e-2)" "unprognostic (7.19e-2)" "unprognostic (8.82e-2)" "unprognostic (2.76e-2)" "unprognostic (9.16e-2)" "unprognostic (7.39e-2)" "unprognostic (6.85e-2)" "unprognostic (4.69e-2)" 25.9 18.4 4.2 17.5 5.4 13.0 9.7 5.5 10.6 11.6 13.6 8.5 6.6 8.0 6.3 6.2 5.6 29.8 8.7 3.8 6.5 6.7 24.9 120.1 7.0 15.0 7.5 6.1 11.4 6.3 2.6 27.4 10.8 3.6 10.6 5.9 6.3 6.4 2.3 3.5 9.4 17.9 6.9 16.0 6.2 6.2 16.9 4.4 5.2 1.4 2.9 17.4 1.9 22.9 1.5 2.1 3.0 1.5 1.4 1.3 1.4 0.7 105.2 0.3 0.6 3.7 0.4 3.4 5.1 1.0 0.7 0.7 0.7 1.0 2.0 0.4 4.3 4.6 5.1 4.2 0.9 2.4 2.5 0.7 0.8 0.8 1.5 1.8 0.2 1.9 1.7 2.9 1.9 4.3 1.4 1.4 0.5 1.6 1.3 40.7 2.3 1.0 2.0 5.8 2.8 1.2 1.0 2.8 0.2 5.0 0.4 1.2 2.4 2.8 0.9 10.8 2.8 9.5 8.6 7.4 1.1 1.5 2.2 1.7 3.3 0.6 1.0 16.9 0.4 1.1 0.7 0.7 1.1 1.5 1.3 0.9 3.2 0.4 8.8 0.5 0.7 0.8 4.2 5.4 5.5 10.6 3.8 6.5 15.0 7.5 10.8 6.9 16.9 22.9 2.0 22.4 35.9 0.0 2.7 2.7 0.0 0.0 0.0 1.6 0.5 1.4 2.0 2.8 8.1 3.7 25.0 0.5 0.1 0.0 1.9 0.0 2.9 0.0 0.0 6.3 0.0 2.7 0.3 0.0 1.0 2.1 0.0 0.0 17.7 0.1 4.6 1.7 137.3 0.0 3.0 0.1 0.0 322.8 86.0 3.6 1.8 172.5 0.0 28.1 3.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.4 6.6 0.7 19.7 1.0 0.7 4.2 1.3 0.1 2.0 0.8 2.6 0.2 0.0 0.3 MSRA ENSG00000175806 "Methionine sulfoxide reductase A" Q9UJ68 8 10054292-10428891 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 86.0;liver: 64.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 625.8;Inhibitory neurons: 318.6;Oligodendrocyte precursor cells: 268.9;Proximal tubular cells: 666.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebellum: 28.4" "Immune cell enhanced" "Detected in some" "eosinophil: 5.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 12.3" "Low region specificity" "Detected in all" "HPA023804, HPA075766" Approved Supported "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" No No 55000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "Plasma membrane, Actin filaments" "HPA023804: AB_1853826, HPA075766: " "unprognostic (1.55e-1)" "unprognostic (4.30e-3)" "unprognostic (1.45e-3)" "unprognostic (1.00e-2)" "unprognostic (4.21e-2)" "unprognostic (1.62e-2)" "unprognostic (1.49e-2)" "unprognostic (6.40e-2)" "unprognostic (9.69e-2)" "unprognostic (1.08e-1)" "unprognostic (1.80e-1)" "unprognostic (4.58e-2)" "unprognostic (1.07e-3)" "unprognostic (6.43e-3)" "unprognostic (4.02e-1)" "unprognostic (6.36e-3)" "unprognostic (3.07e-1)" 17.0 20.4 2.2 1.1 3.0 13.5 16.1 28.4 5.4 9.1 0.0 13.9 1.1 10.7 0.1 11.6 7.4 0.4 29.0 3.8 0.0 86.0 64.0 12.2 0.6 0.0 0.4 6.4 14.5 0.7 9.2 0.8 1.8 9.2 0.6 0.6 10.5 1.0 14.5 9.5 20.1 0.8 0.0 18.6 14.2 15.2 0.3 1.5 9.6 1.3 0.6 11.6 8.2 2.8 0.1 0.9 1.3 4.3 1.2 1.4 0.5 2.5 0.2 0.3 1.7 0.6 2.1 0.0 0.6 2.5 5.8 2.3 0.4 0.1 1.3 0.2 0.0 0.3 1.5 2.2 4.3 0.8 12.3 0.4 3.2 0.3 0.0 1.4 0.6 0.3 0.4 0.2 4.9 0.1 0.0 0.3 0.6 3.3 0.8 1.6 1.3 2.0 1.1 1.1 2.5 1.5 4.6 0.2 0.5 0.4 2.3 2.8 2.6 1.7 2.0 0.4 1.2 0.2 0.1 0.7 4.8 0.8 3.1 0.5 1.9 5.6 0.4 1.2 0.3 0.6 0.4 0.3 1.2 0.1 0.3 0.2 2.2 0.7 0.9 0.2 0.3 0.2 2.2 3.0 28.4 5.4 3.8 0.0 0.0 0.4 1.8 0.0 0.3 2.8 44.1 0.0 7.4 152.8 21.4 16.4 29.3 10.8 14.2 10.1 21.2 21.8 21.6 25.8 7.2 25.8 31.3 7.7 12.4 26.4 92.0 32.3 80.6 13.6 8.7 30.3 9.6 3.4 625.8 47.1 4.6 13.1 14.8 11.8 80.7 13.7 19.6 97.2 47.0 16.8 318.6 20.8 4.1 33.6 48.3 167.9 9.3 38.0 30.2 85.3 22.3 14.6 11.3 268.9 60.7 51.1 37.8 9.8 16.2 33.8 195.5 666.1 5.6 6.2 13.1 11.3 16.9 39.3 26.5 20.1 14.1 8.3 18.0 14.1 24.5 31.1 MSRB3 "DFNB74, DKFZp686C1178, FLJ36866" ENSG00000174099 "Methionine sulfoxide reductase B3" Q8IXL7 12 65278643-65491430 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 12 "Cardiomyocytes: 2801.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 41.6" "Lineage enhanced" "Detected in many" "granulocytes: 41.6" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 126.1;hTERT-RPE1: 110.6;U-937: 106.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014432 Enhanced "Intracellular and membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 32: U-937 - Innate immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA014432: AB_1854146" "unprognostic (1.40e-2)" "prognostic unfavorable (3.84e-4)" "unprognostic (2.86e-3)" "unprognostic (1.94e-1)" "unprognostic (2.74e-2)" "unprognostic (1.74e-2)" "unprognostic (2.63e-2)" "unprognostic (1.23e-1)" "unprognostic (1.84e-2)" "unprognostic (5.33e-2)" "unprognostic (8.28e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (8.85e-8)" "unprognostic (3.29e-3)" "unprognostic (7.80e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (2.17e-4)" 44.9 10.7 12.9 20.9 13.6 21.2 26.3 12.5 12.8 29.5 18.8 108.0 11.9 85.8 20.1 63.0 41.4 33.2 90.8 11.9 18.3 10.1 3.8 30.6 5.7 15.9 15.2 16.9 5.8 3.2 6.8 25.2 13.8 52.7 27.8 12.5 10.8 103.0 104.0 9.7 25.6 123.9 14.6 13.6 36.2 5.8 18.2 4.1 14.5 69.2 3.9 60.9 23.7 11.8 8.8 19.2 16.4 75.9 71.6 63.0 0.5 87.0 92.9 33.2 19.8 0.7 1.0 0.0 18.3 126.1 10.5 1.9 7.7 22.1 30.0 0.2 15.9 0.0 16.7 0.9 46.6 47.1 0.3 33.4 11.9 28.1 39.0 110.6 68.2 0.1 0.3 0.3 76.8 2.9 0.0 11.0 5.4 0.2 10.4 0.2 22.0 0.5 7.5 1.0 0.4 7.9 30.0 1.8 21.9 16.8 14.1 44.5 78.9 42.3 22.8 19.5 34.2 8.0 6.7 0.2 11.5 106.7 26.9 15.0 0.6 41.6 0.2 0.9 0.1 0.1 0.1 0.1 0.2 0.3 0.2 0.2 6.8 8.3 0.4 10.8 0.1 1.4 12.9 13.6 12.5 12.8 11.9 18.3 15.9 15.2 13.8 14.6 18.2 11.8 55.3 12.8 3.4 76.7 0.8 6.4 16.4 11.4 4.0 22.7 2.2 45.3 2801.7 4.3 1.2 3.7 0.0 0.4 8.3 0.0 0.0 9.3 5.7 0.9 16.7 154.2 0.0 17.4 37.1 1.0 0.4 108.8 1.1 0.4 2.5 7.4 28.2 0.2 0.5 21.9 56.6 0.0 0.0 0.0 13.7 2.2 12.5 4.0 10.6 62.8 1.6 44.4 2.1 37.7 1.4 1.6 0.0 116.6 0.3 14.8 0.0 0.4 6.8 10.6 105.2 37.7 218.7 4.2 4.7 0.8 4.5 0.7 2.4 10.3 0.0 2.9 MTCH2 SLC25A50 ENSG00000109919 "Mitochondrial carrier 2" Q9Y6C9 11 47617315-47642607 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 569.2;Proximal tubular cells: 508.1;Spermatocytes: 435.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038390 Approved Approved Mitochondria NA NA 14000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA038390: AB_10669723" "unprognostic (4.94e-2)" "unprognostic (3.29e-1)" "unprognostic (1.93e-2)" "unprognostic (1.43e-1)" "unprognostic (4.27e-1)" "unprognostic (7.63e-3)" "unprognostic (1.80e-1)" "unprognostic (7.03e-2)" "unprognostic (1.51e-1)" "unprognostic (1.53e-2)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "prognostic favorable (9.05e-6)" "unprognostic (1.12e-2)" "unprognostic (8.75e-2)" "unprognostic (2.25e-1)" "unprognostic (1.77e-1)" 28.8 40.3 13.2 14.1 14.1 12.6 25.3 14.3 15.7 20.5 12.7 41.7 38.9 26.8 19.4 50.3 18.9 11.9 41.0 13.8 15.1 57.3 115.3 20.0 14.7 13.3 14.0 13.6 22.6 21.2 18.5 9.9 13.7 18.3 32.7 16.2 29.8 11.9 81.8 28.7 37.6 21.4 12.8 19.6 22.6 69.8 14.7 14.6 21.6 47.5 23.0 23.2 26.1 14.9 47.8 51.2 42.9 57.9 49.7 45.8 31.6 50.5 46.1 66.7 62.6 40.9 47.2 65.4 26.8 62.3 71.7 58.5 77.7 66.4 80.9 33.0 73.4 37.5 69.3 82.5 68.2 79.1 36.1 52.1 51.5 44.3 65.8 38.6 61.1 55.1 70.9 38.0 82.9 69.3 61.1 59.5 46.4 92.4 77.0 56.1 65.4 47.0 78.5 60.6 51.0 35.7 69.1 68.8 37.1 40.3 99.2 36.4 51.2 60.9 52.9 102.4 65.8 40.5 49.3 73.2 50.4 67.7 55.7 13.3 33.8 14.1 20.3 37.6 19.6 25.1 17.7 19.2 44.0 19.5 15.1 17.6 3.2 22.2 31.5 28.9 24.0 34.1 13.2 14.1 14.3 15.7 13.8 15.1 13.3 14.0 13.7 12.8 14.7 14.9 28.4 22.4 35.9 54.9 39.2 47.0 56.0 169.3 44.9 0.0 50.7 41.3 67.8 71.4 84.0 53.3 0.0 82.8 41.2 98.1 181.9 153.3 569.2 48.8 37.5 31.6 79.8 74.6 47.0 109.4 119.1 40.0 46.4 40.1 37.3 29.3 33.2 289.4 164.2 0.0 50.9 97.0 150.5 65.7 40.3 166.5 28.9 67.5 81.8 22.5 103.9 0.0 30.9 58.8 58.6 93.0 69.7 58.3 70.9 84.9 213.3 508.1 79.0 0.0 32.9 30.0 141.3 435.4 104.4 129.8 54.1 127.8 34.5 74.4 165.5 65.2 MTHFD1 "MTHFC, MTHFD" ENSG00000100714 "Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1" 14 64388031-64463457 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 356.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 142.9;Proximal tubular cells: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000704, HPA001290, HPA015006, HPA050052" Approved Enhanced Cytosol NA Yes "Cluster 43: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA000704: AB_1079424, HPA001290: AB_1854177, HPA015006: AB_1854178, HPA050052: AB_2680998" "unprognostic (3.58e-2)" "unprognostic (5.50e-3)" "unprognostic (1.24e-1)" "unprognostic (2.46e-2)" "unprognostic (1.37e-1)" "unprognostic (7.01e-2)" "unprognostic (8.85e-3)" "unprognostic (7.62e-3)" "unprognostic (1.28e-1)" "unprognostic (2.29e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.84e-1)" "prognostic favorable (5.93e-5)" "unprognostic (2.45e-2)" "unprognostic (1.75e-1)" "unprognostic (7.30e-2)" "unprognostic (2.29e-2)" 56.4 18.0 8.6 20.0 17.4 27.0 29.8 8.3 12.3 16.9 15.0 23.3 19.7 16.1 9.9 25.1 16.0 13.1 28.1 12.9 8.1 55.3 356.9 15.4 23.6 7.5 7.8 24.9 23.8 27.5 9.2 13.3 7.0 12.9 27.5 3.6 15.6 13.8 64.1 17.1 18.9 20.0 7.2 14.5 17.9 4.7 8.9 30.2 20.5 61.9 27.7 18.6 16.6 8.3 294.1 164.9 58.5 143.6 70.5 53.4 95.7 106.4 83.3 148.1 147.4 161.2 144.2 103.3 49.6 67.1 68.3 146.0 177.6 111.2 160.4 107.3 117.9 122.2 143.5 131.8 50.6 104.5 81.2 43.0 37.3 124.3 66.4 57.5 93.1 98.1 108.5 98.7 114.7 270.1 179.9 62.3 118.0 186.5 160.4 138.3 201.2 114.4 110.5 160.9 128.7 49.0 183.7 111.4 58.3 54.0 164.4 58.6 51.5 115.1 184.1 102.2 134.2 58.8 65.6 177.9 107.4 125.2 134.8 0.4 11.7 0.1 9.7 19.5 13.0 27.0 10.1 12.3 17.7 15.3 7.8 10.7 0.9 17.8 16.7 4.0 19.5 12.2 8.6 17.4 8.3 12.3 12.9 8.1 7.5 7.8 7.0 7.2 8.9 8.3 8.1 19.2 23.5 15.0 16.2 13.8 14.2 14.7 13.6 0.0 9.8 8.1 43.9 15.7 19.5 16.5 0.0 30.6 10.8 7.9 41.1 16.9 1.4 6.8 11.7 12.3 3.0 42.3 19.5 10.3 30.9 14.9 15.3 8.7 50.7 27.2 12.8 142.9 25.3 0.0 15.6 14.3 2.0 13.0 11.0 1.5 13.1 12.3 14.2 8.4 13.3 0.0 8.2 14.1 10.9 11.7 6.3 13.2 24.1 10.2 8.2 75.3 11.5 0.0 19.7 13.1 19.3 0.9 8.9 19.5 10.7 9.9 16.6 21.4 24.6 12.7 MTHFS HsT19268 ENSG00000136371 "Methenyltetrahydrofolate synthetase" P49914 15 79833585-79897379 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 253.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 205.5;monocytes: 150.8;Proximal tubular cells: 201.6;Syncytiotrophoblasts: 253.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 134.1" "Group enriched" "Detected in all" 5 "granulocytes: 134.1;monocytes: 49.1" "Low cell line specificity" "Detected in many" "HPA008067, HPA054177" Approved Supported Cytosol NA NA 13000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA008067: AB_1078882, HPA054177: AB_2682405" "unprognostic (4.57e-2)" "unprognostic (9.76e-2)" "unprognostic (6.11e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (8.52e-4)" "unprognostic (9.13e-3)" "prognostic favorable (1.29e-6)" "unprognostic (1.34e-2)" "unprognostic (1.03e-1)" "unprognostic (6.18e-3)" "unprognostic (2.91e-2)" "unprognostic (2.76e-1)" "prognostic favorable (2.04e-4)" "unprognostic (1.36e-1)" "unprognostic (2.85e-1)" "unprognostic (7.60e-2)" "unprognostic (2.90e-1)" 21.9 19.8 8.0 4.6 8.2 5.0 19.0 9.6 12.7 9.9 6.9 12.0 13.7 9.0 10.3 10.1 9.4 7.0 19.0 8.0 9.2 53.1 253.4 17.8 6.4 8.7 9.3 8.6 32.8 26.3 21.5 8.3 9.1 19.5 6.4 5.9 13.6 5.5 20.2 6.2 14.5 6.2 8.8 14.9 19.5 12.1 8.7 10.6 15.9 11.1 10.8 12.4 9.9 9.1 12.6 35.8 5.0 2.6 15.8 12.0 11.9 8.8 13.0 16.4 10.5 34.5 22.4 15.1 25.1 15.5 15.0 19.5 31.9 10.7 15.4 14.7 28.4 14.8 22.9 39.8 25.3 7.8 0.8 17.5 27.8 8.1 23.0 19.6 7.4 16.0 28.8 12.0 17.4 36.0 10.2 36.1 15.6 51.4 17.0 10.8 17.2 25.8 35.1 34.3 8.9 4.8 25.1 14.2 43.8 20.0 17.3 13.0 3.3 5.7 11.1 3.6 7.1 6.8 20.2 17.8 3.3 25.9 6.2 17.5 25.7 73.5 9.4 35.3 12.4 13.5 13.7 12.9 12.3 11.1 16.5 12.6 134.1 17.8 49.1 13.3 15.7 19.1 8.0 8.2 9.6 12.7 8.0 9.2 8.7 9.3 9.1 8.8 8.7 9.1 11.3 19.2 44.0 0.0 20.7 10.7 9.9 63.0 35.9 0.0 25.5 32.5 0.7 58.6 34.3 22.0 0.0 68.1 10.1 10.0 64.6 55.8 2.2 11.9 7.8 10.5 17.6 36.6 0.0 75.7 37.1 13.5 39.8 11.0 8.8 7.2 21.8 205.5 45.7 0.0 0.0 18.7 24.4 22.1 34.8 3.8 13.7 29.3 21.4 0.0 150.8 0.0 35.0 0.0 0.0 75.3 35.9 15.8 13.3 13.3 101.7 201.6 29.9 0.0 13.1 8.4 10.5 6.7 8.5 21.1 8.1 253.8 22.2 9.2 24.9 7.7 MYCT1 "FLJ21269, MTLC" ENSG00000120279 "MYC target 1" Q8N699 6 152697895-152724567 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 49.6" "Group enriched" "Detected in some" 5 "Adipocytes: 123.0;Endothelial cells: 141.3;Hepatic stellate cells: 230.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 33 "eosinophil: 30.7" "Lineage enriched" "Detected in single" 248 "granulocytes: 30.7" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 124.6;TIME: 104.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047992 Approved Nucleoplasm,Vesicles NA NA 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Vesicles "HPA047992: " "unprognostic (2.92e-1)" "unprognostic (1.82e-1)" "unprognostic (5.95e-2)" "unprognostic (2.06e-1)" "unprognostic (6.73e-2)" "unprognostic (6.80e-2)" "unprognostic (4.64e-3)" "unprognostic (6.78e-2)" "unprognostic (9.90e-2)" "unprognostic (2.10e-1)" "unprognostic (2.66e-2)" "unprognostic (2.18e-2)" "prognostic unfavorable (4.73e-4)" "unprognostic (1.26e-3)" "unprognostic (1.08e-1)" "unprognostic (1.25e-1)" "unprognostic (3.36e-2)" 26.6 3.2 6.8 5.2 6.9 1.2 21.4 6.9 10.2 9.0 5.2 6.1 3.5 10.1 4.5 4.6 9.2 10.5 17.1 6.3 7.1 6.6 13.1 15.6 6.2 7.7 6.9 3.6 2.7 4.3 2.2 20.7 8.6 4.4 5.8 1.0 3.7 3.8 12.8 4.7 5.6 12.4 6.8 49.6 4.5 1.8 10.0 2.5 12.2 20.5 3.0 8.1 7.3 7.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 17.7 0.1 0.0 0.2 0.0 0.1 0.0 23.0 0.3 0.0 0.7 0.1 0.1 0.0 0.2 0.2 0.3 0.0 124.6 0.0 0.3 0.3 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 2.1 0.0 0.0 104.4 0.5 0.8 1.5 0.0 1.1 0.0 15.6 0.0 0.0 0.0 0.9 0.0 30.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.6 6.8 6.9 6.9 10.2 6.3 7.1 7.7 6.9 8.6 6.8 10.0 7.5 123.0 0.0 5.2 0.7 0.8 7.1 0.2 0.1 2.8 0.2 0.4 0.9 3.1 2.8 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 10.2 1.3 0.2 141.3 0.0 13.7 0.1 0.2 0.0 4.0 0.0 0.1 1.3 0.0 230.6 2.1 0.1 0.0 0.1 0.0 0.0 7.3 7.3 3.7 0.3 13.3 14.2 30.9 0.1 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.6 0.5 0.0 0.0 17.7 0.0 0.0 1.5 2.2 0.1 0.1 0.5 5.5 0.0 0.9 0.5 0.0 0.7 MYH10 NMMHCB ENSG00000133026 "Myosin heavy chain 10" P35580 17 8474207-8630761 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 171.9;Excitatory neurons: 221.3;Inhibitory neurons: 151.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 216.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017180, HPA047541, HPA057198" Enhanced Supported "Actin filaments,Mitochondria,Cytosol" NA NA 28000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" "Actin filaments" "Mitochondria, Cytosol" "CAB017180: , HPA047541: AB_2680081, HPA057198: AB_2683364" "unprognostic (4.67e-2)" "unprognostic (9.64e-3)" "unprognostic (1.13e-1)" "unprognostic (2.52e-3)" "unprognostic (2.40e-1)" "unprognostic (2.33e-2)" "unprognostic (2.75e-1)" "unprognostic (6.45e-2)" "unprognostic (4.77e-2)" "unprognostic (1.11e-1)" "unprognostic (1.39e-3)" "unprognostic (1.69e-2)" "prognostic favorable (1.38e-4)" "unprognostic (2.02e-2)" "unprognostic (2.73e-1)" "unprognostic (5.58e-2)" "prognostic unfavorable (6.42e-4)" 27.3 16.9 12.6 6.1 18.9 13.4 14.7 7.0 29.0 19.6 12.6 12.2 2.3 27.8 16.8 6.6 25.2 26.1 38.9 17.9 8.0 32.5 18.9 66.9 6.5 9.6 7.3 25.9 9.8 13.8 17.7 53.4 9.6 17.7 3.8 22.5 6.6 26.6 4.9 7.9 5.8 22.1 0.5 4.6 9.5 7.4 11.0 5.8 13.6 8.2 4.0 10.5 10.3 13.2 54.1 35.1 216.3 72.7 27.7 33.1 97.1 44.2 39.7 52.2 55.8 94.5 8.0 0.5 28.6 43.9 28.4 5.2 108.7 53.0 58.1 1.2 88.3 62.3 21.7 83.0 64.7 5.4 4.2 47.3 18.9 67.7 26.1 32.1 85.3 70.9 88.1 0.2 32.9 21.6 67.2 1.7 102.1 3.6 7.7 105.9 64.2 0.2 59.1 22.3 17.7 96.8 69.2 3.4 68.1 165.0 18.3 3.6 2.8 48.7 35.6 0.3 38.5 8.3 10.8 13.4 0.3 5.0 111.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 12.6 18.9 7.0 29.0 17.9 8.0 9.6 7.3 9.6 0.5 11.0 13.2 43.0 22.4 14.1 43.1 1.1 4.7 9.5 11.2 9.6 37.1 18.7 16.4 33.5 12.8 11.5 101.2 50.1 171.9 1.0 0.8 17.6 13.7 49.1 28.1 37.6 30.6 2.4 43.5 221.3 1.7 88.6 58.0 3.1 28.5 1.3 41.6 55.6 15.3 15.8 35.3 151.1 1.9 6.1 2.7 3.7 28.6 3.7 1.3 1.8 15.9 0.7 25.9 2.1 96.5 15.5 1.9 0.7 39.9 0.6 7.6 0.0 14.0 21.7 39.4 0.0 12.4 23.6 15.6 27.8 9.5 4.0 76.5 2.0 28.0 2.2 4.4 MYH14 "DFNA4, FLJ13881, KIAA2034, MHC16, MYH17" ENSG00000105357 "Myosin heavy chain 14" Q7Z406 19 50188186-50310542 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Deafness, Disease variant, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 191.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 487.2;Paneth cells: 306.4;Proximal enterocytes: 376.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 48.6;CAPAN-2: 59.4;HaCaT: 119.0;MCF7: 59.0;OE19: 61.7;RT4: 147.8;SK-BR-3: 51.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062391, HPA067889, HPA070260" Enhanced Approved Nucleoplasm NA NA 9600000 "Cluster 80: Striated muscle - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA062391: AB_2684748, HPA067889: AB_2685917, HPA070260: AB_2686243" "unprognostic (2.52e-1)" "unprognostic (5.81e-2)" "unprognostic (9.63e-2)" "unprognostic (3.73e-3)" "unprognostic (1.44e-1)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (1.79e-1)" "unprognostic (1.71e-1)" "unprognostic (3.48e-2)" "unprognostic (1.93e-2)" "unprognostic (1.01e-1)" "prognostic favorable (3.97e-8)" "prognostic favorable (7.83e-4)" "unprognostic (8.50e-2)" "unprognostic (3.12e-1)" "unprognostic (2.77e-1)" 12.6 1.0 24.1 7.0 35.0 0.0 8.8 38.2 23.3 13.3 22.0 64.5 83.8 1.5 0.2 63.7 15.4 3.6 41.3 20.0 30.9 10.2 25.4 24.4 0.1 38.7 35.6 0.4 17.3 16.7 18.5 0.4 35.7 8.8 19.5 5.1 44.0 5.7 191.3 87.7 76.7 1.3 29.5 0.1 45.5 2.6 34.4 1.5 33.2 35.1 6.1 11.0 31.8 37.4 48.6 5.0 0.0 25.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 33.1 59.4 0.2 30.1 0.0 3.7 119.0 0.1 0.0 0.0 0.1 8.7 0.0 0.0 25.7 0.0 0.0 17.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.4 0.2 0.0 59.0 0.0 0.3 0.8 61.7 0.7 0.1 29.4 0.7 0.0 147.8 0.1 0.2 2.9 51.8 0.0 0.2 9.7 1.9 0.0 0.1 11.7 0.2 0.1 0.9 11.2 0.3 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.1 35.0 38.2 23.3 20.0 30.9 38.7 35.6 35.7 29.5 34.4 37.4 0.1 80.1 36.5 23.5 2.8 3.3 18.7 29.3 0.0 3.7 17.9 9.3 21.8 44.3 50.9 57.0 2.1 0.1 0.3 487.2 0.0 53.2 0.9 58.1 6.0 1.2 51.6 0.0 10.9 27.2 0.1 1.1 85.1 70.7 14.7 0.0 2.9 45.8 0.1 16.8 21.7 109.4 22.4 0.8 1.6 0.8 0.3 1.3 5.4 2.8 0.0 19.7 0.0 23.6 27.5 67.5 306.4 0.0 0.3 30.8 376.1 7.6 80.6 11.5 0.0 17.7 3.5 0.5 4.6 30.8 21.0 0.0 2.0 0.0 122.8 86.2 MYH7B "dJ756N5.1, KIAA1512, MHC14, MYH14" ENSG00000078814 "Myosin heavy chain 7B" A7E2Y1 20 34955810-35002437 "Predicted intracellular proteins" "Actin-binding, Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "heart muscle: 352.2;skeletal muscle: 157.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 86.6;Early spermatids: 34.0;Late spermatids: 67.9" "Cancer enhanced" "Detected in many" "endometrial cancer: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.6;U-138 MG: 1.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (4.05e-4)" "unprognostic (1.64e-1)" "unprognostic (1.66e-2)" "unprognostic (2.71e-1)" "unprognostic (5.36e-2)" "unprognostic (1.46e-2)" "unprognostic (3.89e-2)" "unprognostic (5.44e-2)" "unprognostic (4.87e-1)" "unprognostic (4.72e-2)" "unprognostic (4.41e-3)" "unprognostic (1.92e-1)" "unprognostic (1.02e-4)" "unprognostic (8.31e-3)" "unprognostic (1.70e-1)" "unprognostic (2.66e-1)" "prognostic favorable (8.44e-5)" 1.3 1.0 13.4 0.3 17.4 0.5 1.4 11.0 15.7 3.5 5.9 1.8 1.2 1.9 1.3 1.7 2.5 0.6 352.2 10.5 13.1 2.8 2.3 1.4 0.5 14.8 14.2 4.5 1.1 0.0 3.5 0.2 18.5 4.9 0.1 2.2 2.8 0.4 157.2 1.1 1.4 0.2 10.9 1.4 0.9 29.0 21.1 0.2 3.4 26.7 0.1 1.2 1.7 24.0 0.9 0.3 0.2 0.3 0.0 0.2 0.6 0.0 0.0 0.0 0.0 1.6 0.5 0.2 0.6 0.0 0.2 0.5 0.0 0.0 0.1 0.1 0.2 0.5 0.6 0.7 0.1 0.2 0.3 0.2 0.1 0.0 0.0 0.6 0.0 0.7 0.2 0.5 0.1 0.4 0.1 0.9 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.3 0.4 0.1 0.2 0.2 0.2 1.3 0.3 0.4 1.5 0.7 0.2 0.2 0.9 0.1 0.3 0.4 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 13.4 17.4 11.0 15.7 10.5 13.1 14.8 14.2 18.5 10.9 21.1 24.0 0.6 0.0 5.6 7.5 1.1 3.6 1.6 0.1 1.2 16.5 1.2 1.0 86.6 1.5 0.7 5.5 8.4 1.3 0.3 0.5 0.0 0.5 34.0 0.7 1.0 2.1 0.0 0.0 3.4 0.6 0.6 2.2 0.0 1.0 1.3 2.0 1.8 0.2 0.4 10.1 3.8 0.5 0.0 1.6 2.1 67.9 2.1 1.2 0.0 2.8 0.5 4.3 0.0 1.5 17.3 0.6 0.1 3.4 0.6 1.1 0.6 0.6 0.3 14.1 6.6 9.4 2.5 11.0 6.3 0.3 5.4 0.8 0.9 1.5 1.0 0.9 MYO7B ENSG00000169994 "Myosin VIIB" Q6PIF6 2 127535802-127637729 "Predicted intracellular proteins" Differentiation "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 113.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 127.7;Intestinal goblet cells: 48.3;Paneth cells: 74.9;Proximal enterocytes: 151.4;Undifferentiated cells: 45.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 17.2" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.7;naive B-cell: 5.9" "Group enriched" "Detected in many" 22 "B-cells: 5.9;dendritic cells: 2.6;monocytes: 5.7" "Cell line enriched" "Detected in some" 10 "MOLT-4: 286.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA039131 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" "HPA039131: AB_10672771" "unprognostic (4.10e-3)" "unprognostic (3.81e-2)" "unprognostic (3.80e-2)" "unprognostic (2.23e-4)" "unprognostic (1.14e-2)" "unprognostic (2.23e-1)" "unprognostic (2.07e-1)" "unprognostic (8.51e-2)" "unprognostic (3.76e-1)" "unprognostic (3.86e-2)" "unprognostic (2.32e-1)" "unprognostic (1.03e-1)" "prognostic favorable (1.25e-4)" "unprognostic (2.80e-2)" "unprognostic (8.76e-2)" "unprognostic (1.57e-1)" "unprognostic (2.88e-1)" 0.1 0.0 0.2 4.9 0.2 6.5 0.1 0.2 0.3 0.0 0.0 35.9 113.2 0.0 6.7 0.3 0.4 13.0 0.2 0.7 1.8 8.5 0.3 1.0 4.0 0.5 1.1 0.0 0.2 0.0 0.0 1.7 1.1 0.1 25.3 0.0 0.1 0.2 0.8 0.3 84.4 1.2 0.5 11.3 0.4 1.4 0.3 9.0 0.2 0.0 1.6 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.0 14.5 5.1 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.2 0.0 28.1 0.0 0.0 0.2 0.0 286.1 0.8 0.0 0.5 1.7 0.5 1.9 0.3 0.5 0.0 0.1 0.1 0.0 2.4 0.0 0.0 0.1 0.5 0.1 0.6 8.6 0.4 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.7 0.1 0.0 2.2 0.0 0.8 0.0 0.0 2.6 5.9 0.0 0.2 0.1 0.0 1.4 0.7 0.0 2.4 0.2 0.2 0.2 0.3 0.7 1.8 0.5 1.1 1.1 0.5 0.3 0.8 2.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 12.8 0.0 5.5 0.0 0.1 1.5 127.7 1.9 0.2 0.1 0.0 0.0 1.0 25.8 0.0 0.2 0.2 2.0 0.1 1.5 0.0 0.0 0.1 2.9 0.2 0.1 0.0 0.4 48.3 0.0 0.0 0.3 0.4 0.0 1.0 0.0 0.0 0.8 0.0 0.0 0.5 0.1 1.6 74.9 0.0 0.0 0.0 151.4 9.9 0.0 0.0 0.0 2.8 0.1 0.6 1.1 0.0 0.1 0.3 0.6 0.0 45.7 0.1 NAALAD2 "GCPIII, NAALADASE2" ENSG00000077616 "N-acetylated alpha-linked acidic dipeptidase 2" Q9Y3Q0 11 90131515-90192894 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Dipeptidase, Hydrolase, Metalloprotease, Multifunctional enzyme, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 19.9;testis: 13.9" "Group enriched" "Detected in many" 4 "Early spermatids: 39.7;Excitatory neurons: 109.3;Horizontal cells: 70.7;Inhibitory neurons: 110.2;Oligodendrocyte precursor cells: 153.8;Oligodendrocytes: 83.7" "Cancer enhanced" "Detected in some" "testis cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 19.2;SH-SY5Y: 6.1;SuSa: 4.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA060820, HPA065419" Approved Approved Nucleoplasm NA NA "Cluster 43: Testis - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA060820: AB_2684373, HPA065419: AB_2685487" "unprognostic (1.68e-1)" "unprognostic (2.66e-3)" "unprognostic (1.49e-1)" "unprognostic (4.52e-3)" "unprognostic (4.73e-3)" "unprognostic (2.97e-1)" "unprognostic (3.82e-3)" "unprognostic (1.77e-2)" "unprognostic (2.44e-1)" "unprognostic (2.30e-1)" "unprognostic (3.30e-2)" "unprognostic (8.00e-2)" "unprognostic (9.97e-4)" "unprognostic (1.52e-2)" "unprognostic (2.54e-1)" "unprognostic (1.63e-2)" "unprognostic (2.93e-1)" 3.8 10.0 2.3 0.4 3.3 0.1 3.3 1.5 5.3 10.3 0.0 1.9 0.2 4.1 1.9 0.8 3.4 1.2 2.1 2.4 2.8 1.5 0.9 2.1 0.4 3.6 3.5 7.4 0.7 0.1 19.9 3.5 3.4 3.2 0.6 3.5 1.1 1.2 1.1 0.7 1.3 1.1 2.0 2.6 1.2 13.9 3.0 0.1 1.4 0.7 0.1 2.2 4.0 4.2 0.1 0.2 1.8 0.1 0.5 0.1 2.2 0.1 0.1 0.1 0.0 19.2 0.7 0.3 0.2 0.0 0.3 0.3 1.3 0.0 0.0 0.0 0.3 1.9 0.4 1.7 0.2 0.1 0.1 1.9 0.0 0.0 0.0 0.5 0.4 0.2 0.1 0.0 0.0 0.0 0.3 0.3 1.8 0.5 0.2 0.3 0.0 0.2 0.0 0.0 0.2 6.1 0.0 0.2 0.0 4.3 0.2 0.4 2.4 0.1 1.4 0.3 0.3 1.0 0.3 0.3 0.6 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.3 3.3 1.5 5.3 2.4 2.8 3.6 3.5 3.4 2.0 3.0 4.2 2.6 0.0 0.0 3.3 0.1 0.3 0.1 0.0 0.0 17.3 0.0 0.0 2.4 1.5 0.6 0.0 0.0 1.2 0.1 0.0 0.0 0.1 39.7 0.8 13.7 1.2 0.0 0.0 109.3 0.0 0.6 7.5 1.1 0.6 0.0 1.7 0.7 0.2 0.3 70.7 110.2 0.0 0.0 7.2 0.4 17.7 11.1 0.5 0.0 12.2 0.0 8.4 0.0 153.8 83.7 0.0 0.0 14.7 0.4 0.4 0.0 0.1 0.0 2.4 0.0 6.4 4.6 0.6 11.3 0.4 0.0 0.8 0.2 19.4 0.2 0.1 NAALADL1 ENSG00000168060 "N-acetylated alpha-linked acidic dipeptidase like 1" Q9UQQ1 11 65044818-65058553 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "intestine: 99.3" "Cell type enriched" "Detected in many" 11 "Proximal enterocytes: 588.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 182.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.8;fHDF/TERT166: 7.8;HHSteC: 20.2;HSkMC: 13.5;SCLC-21H: 10.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA047123 Enhanced Uncertain Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 9: Intestine - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Cytosol "HPA047123: AB_2679942" "unprognostic (2.98e-2)" "unprognostic (2.06e-1)" "unprognostic (1.58e-1)" "unprognostic (8.76e-2)" "unprognostic (1.70e-1)" "unprognostic (1.28e-3)" "unprognostic (1.36e-1)" "unprognostic (1.40e-1)" "unprognostic (1.89e-2)" "unprognostic (1.38e-1)" "unprognostic (3.03e-1)" "unprognostic (2.18e-1)" "unprognostic (1.75e-4)" "unprognostic (2.10e-3)" "unprognostic (3.22e-2)" "unprognostic (1.45e-1)" "unprognostic (4.80e-2)" 13.9 3.2 4.4 6.6 4.1 21.1 12.1 4.7 6.0 23.5 7.0 18.4 19.8 18.8 4.6 7.3 15.2 9.4 10.5 3.9 4.1 7.4 2.6 10.9 10.9 4.7 4.3 16.6 2.3 2.0 6.0 2.3 4.6 13.8 7.1 1.9 4.9 11.5 2.7 5.4 99.3 10.5 4.6 15.3 8.2 8.7 4.4 3.4 5.7 4.1 6.9 12.7 14.5 4.0 0.0 0.0 0.1 0.2 0.5 5.8 1.0 2.3 0.0 2.8 1.3 0.0 0.0 0.1 0.0 7.8 0.0 0.0 0.0 0.2 0.1 0.9 0.4 0.0 0.2 3.5 20.2 0.0 0.0 13.5 0.0 2.7 0.0 0.1 3.6 0.1 0.0 0.3 0.0 0.2 0.2 0.7 0.0 0.1 0.1 0.1 0.0 1.0 0.2 0.0 10.5 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.8 0.0 0.1 0.1 182.0 21.2 35.9 29.6 14.6 15.8 25.7 23.8 14.8 16.3 29.8 27.0 15.0 3.7 80.2 8.8 0.7 45.2 24.6 4.4 4.1 4.7 6.0 3.9 4.1 4.7 4.3 4.6 4.6 4.4 4.0 19.1 0.0 0.0 0.0 8.0 3.6 3.4 5.6 6.2 2.0 0.8 9.1 1.8 1.5 0.4 0.0 0.0 0.2 9.8 31.3 3.9 0.1 0.8 0.4 5.8 11.1 1.2 2.5 0.3 0.8 0.3 11.4 1.1 0.2 19.7 4.3 16.8 0.4 2.8 10.1 0.4 21.0 2.0 5.6 5.7 2.6 11.8 5.2 16.0 1.0 17.3 12.2 41.2 1.0 0.1 0.2 50.0 18.0 1.1 0.5 588.6 0.5 0.5 0.9 0.0 8.3 11.1 1.6 3.5 1.3 3.3 0.4 11.1 3.9 11.8 0.4 NALCN "bA430M15.1, CanIon, VGCNL1" ENSG00000102452 "Sodium leak channel, non-selective" Q8IZF0 13 101053776-101416508 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.1" "Group enriched" "Detected in some" 10 "Astrocytes: 125.4;Excitatory neurons: 265.8;Inhibitory neurons: 277.4;Oligodendrocyte precursor cells: 324.7;Oligodendrocytes: 477.4" "Cancer enhanced" "Detected in some" "glioma: 1.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 2.6" "Lineage enriched" "Detected in single" 7 "granulocytes: 2.6" "Cell line enhanced" "Detected in many" "HaCaT: 14.2;HHSteC: 14.4;hTERT-RPE1: 11.0;TIME: 19.8;U-87 MG: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031889, HPA031890, HPA031958" Approved NA NA "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA031889: AB_10669638, HPA031890: AB_10696056, HPA031958: AB_10601039" "unprognostic (4.66e-1)" "unprognostic (6.55e-3)" "unprognostic (1.86e-3)" "unprognostic (6.78e-3)" "unprognostic (1.16e-1)" "unprognostic (1.37e-3)" "unprognostic (8.11e-2)" "unprognostic (2.60e-1)" "unprognostic (7.72e-2)" "unprognostic (5.92e-2)" "unprognostic (1.25e-1)" "unprognostic (2.18e-1)" "unprognostic (1.58e-5)" "unprognostic (1.77e-3)" "unprognostic (5.44e-2)" "unprognostic (4.56e-2)" "unprognostic (1.92e-2)" 0.5 4.3 7.5 0.4 9.8 0.6 2.7 6.4 10.3 1.5 0.0 0.4 0.6 0.5 1.5 0.2 1.0 2.3 3.3 8.6 10.2 0.3 1.2 1.1 0.3 8.2 5.8 2.8 1.3 2.9 6.8 3.0 7.0 0.3 0.6 6.1 0.8 1.0 0.3 0.5 0.5 0.5 6.8 0.4 0.7 0.6 8.3 0.0 2.4 0.2 0.1 0.5 0.2 13.1 0.1 7.8 1.4 0.2 0.7 0.3 0.1 0.8 0.8 1.8 0.4 0.2 8.9 0.0 0.3 3.6 0.8 14.2 0.0 2.2 5.5 0.0 1.2 0.4 3.8 0.1 14.4 0.2 0.3 0.4 0.5 1.7 4.6 11.0 8.2 0.1 0.1 0.4 5.9 0.0 0.1 0.0 0.4 1.3 1.8 0.0 0.0 0.0 4.6 1.9 1.2 0.6 0.1 0.0 0.8 0.9 0.2 0.1 19.8 0.4 0.1 0.3 1.8 0.1 0.1 0.1 11.4 0.1 0.3 2.6 0.1 0.2 0.3 0.0 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.1 0.5 0.2 0.1 0.2 0.1 0.1 7.5 9.8 6.4 10.3 8.6 10.2 8.2 5.8 7.0 6.8 8.3 13.1 0.1 0.0 0.0 125.4 0.0 0.3 0.0 0.3 0.6 15.4 3.5 4.6 6.2 0.0 0.1 0.0 6.2 1.0 0.0 0.0 0.0 0.8 4.5 0.1 0.2 0.6 0.0 0.0 265.8 0.2 0.2 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 26.9 277.4 0.0 0.0 0.0 0.0 0.9 0.3 0.1 0.0 23.4 0.0 2.0 0.0 324.7 477.4 0.3 0.0 1.9 0.0 0.0 0.0 0.1 0.0 2.6 0.0 3.6 0.5 0.2 0.8 0.0 0.1 0.5 0.0 0.1 0.0 0.0 NAPEPLD "C7orf18, FMP30, NAPE-PLD" ENSG00000161048 "N-acyl phosphatidylethanolamine phospholipase D" Q6IQ20 7 103099776-103149560 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Early spermatids: 128.0;Excitatory neurons: 99.2;Oligodendrocyte precursor cells: 126.7;Oligodendrocytes: 193.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019832, HPA024338" Approved Approved Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 18: U-2197 - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA019832: AB_1844422, HPA024338: AB_2671533" "unprognostic (3.62e-1)" "unprognostic (1.86e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-1)" "unprognostic (7.58e-2)" "unprognostic (1.05e-3)" "unprognostic (1.02e-2)" "unprognostic (6.39e-3)" "unprognostic (2.70e-2)" "unprognostic (1.20e-1)" "unprognostic (2.81e-2)" "unprognostic (3.21e-1)" "prognostic favorable (7.32e-6)" "unprognostic (8.83e-2)" "unprognostic (1.19e-1)" "unprognostic (1.42e-1)" "unprognostic (2.41e-2)" 2.0 4.6 1.6 3.6 3.7 2.0 1.7 1.5 4.2 3.6 0.0 7.7 14.5 3.6 2.2 1.9 5.3 5.9 4.0 1.7 0.0 14.9 7.4 3.0 3.3 0.4 1.1 8.6 3.5 6.0 1.5 2.2 0.8 4.5 7.5 4.8 1.7 3.4 2.4 3.1 9.7 3.0 0.5 6.4 9.9 6.7 2.5 3.0 8.2 2.4 2.7 3.5 1.8 9.2 6.9 7.4 5.1 4.3 4.9 4.9 0.9 5.4 3.1 1.6 3.3 2.7 6.3 5.2 7.7 1.7 6.3 5.6 3.3 0.5 3.8 6.9 6.0 1.9 4.1 1.5 1.1 3.3 2.2 2.8 0.9 1.6 0.0 12.5 3.5 3.5 2.0 4.8 5.0 2.2 5.1 2.4 4.7 9.4 9.7 3.6 2.8 1.9 10.5 2.9 3.8 4.6 10.7 3.7 2.7 3.1 2.4 4.4 4.6 7.7 4.0 17.8 4.9 6.8 8.6 3.7 7.6 2.9 14.8 0.1 1.9 3.7 2.7 2.9 2.3 4.6 3.1 3.4 2.1 4.5 4.4 3.2 0.2 1.5 1.9 1.7 2.9 1.4 1.6 3.7 1.5 4.2 1.7 0.0 0.4 1.1 0.8 0.5 2.5 9.2 4.6 19.2 10.0 38.8 13.2 6.6 5.5 5.3 9.6 78.1 5.7 5.0 12.3 17.2 6.8 53.3 52.1 8.1 5.6 37.5 9.8 5.3 128.0 27.5 10.7 5.2 13.8 36.6 99.2 2.6 4.0 7.3 41.3 42.9 4.5 12.0 4.6 19.1 3.9 50.5 56.7 27.0 4.1 5.5 1.8 43.8 31.7 4.4 14.2 21.5 7.2 16.1 18.6 126.7 193.3 5.0 28.7 33.4 10.6 6.5 46.5 32.6 3.0 35.4 6.6 7.8 6.3 21.1 12.2 3.1 2.8 2.9 8.1 18.9 26.8 7.8 NARS2 "DFNB94, FLJ23441, SLM5" ENSG00000137513 "Asparaginyl-tRNA synthetase 2, mitochondrial" Q96I59 11 78435968-78574874 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease variant, Leigh syndrome, Non-syndromic deafness, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026793 Supported Approved Nucleoplasm,Mitochondria,Cytosol No No "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Mitochondria" Cytosol "HPA026793: AB_1848833" "unprognostic (1.80e-1)" "unprognostic (1.95e-1)" "unprognostic (5.73e-3)" "unprognostic (1.79e-3)" "unprognostic (1.40e-2)" "unprognostic (2.05e-1)" "unprognostic (1.28e-1)" "unprognostic (5.62e-2)" "unprognostic (4.62e-3)" "prognostic favorable (1.39e-5)" "unprognostic (1.96e-1)" "unprognostic (1.56e-1)" "prognostic favorable (1.22e-6)" "unprognostic (8.57e-2)" "unprognostic (1.45e-1)" "unprognostic (2.93e-1)" "unprognostic (1.60e-1)" 7.3 11.9 10.7 6.8 12.3 6.2 11.1 12.4 13.3 9.6 19.8 11.3 10.3 9.1 11.2 8.1 9.9 7.0 11.7 10.4 11.7 19.0 23.5 7.6 9.6 11.7 13.9 11.4 10.6 11.4 7.6 8.0 13.1 10.8 10.9 13.4 10.7 7.3 23.5 7.2 9.7 7.4 11.3 7.4 9.9 7.5 11.4 11.7 11.5 19.6 9.7 8.7 8.1 12.3 16.7 22.8 23.5 15.4 16.1 13.5 19.5 13.5 13.1 20.6 16.9 39.4 17.4 40.9 34.1 8.7 19.8 21.5 39.9 26.3 28.3 27.0 21.3 28.9 17.3 33.7 13.3 31.3 10.1 9.4 16.8 18.1 32.0 18.3 17.9 33.7 44.5 11.0 23.1 19.4 32.7 50.3 25.6 67.3 27.3 33.6 38.2 55.5 27.2 23.0 27.8 17.5 20.1 25.4 35.5 25.1 24.1 12.3 10.9 27.7 32.8 32.0 23.1 18.1 33.1 91.1 5.4 27.7 19.2 9.5 9.3 4.4 11.1 10.4 13.8 17.6 12.8 12.5 16.6 15.0 18.5 16.7 2.0 20.3 12.8 12.7 10.5 10.3 10.7 12.3 12.4 13.3 10.4 11.7 11.7 13.9 13.1 11.3 11.4 12.3 5.8 19.2 26.4 27.7 14.5 13.5 14.2 12.0 12.5 5.2 9.4 6.5 8.8 5.7 10.3 5.5 2.1 20.0 4.4 4.0 29.4 9.5 13.1 10.1 7.4 6.6 12.0 9.2 34.7 7.3 23.6 9.0 10.2 9.0 8.2 14.0 2.5 19.8 12.4 0.0 45.1 8.3 22.4 6.3 11.6 5.4 7.8 6.3 17.8 45.0 2.9 6.3 4.1 42.7 47.7 7.5 9.9 4.9 14.6 17.5 7.0 28.9 10.2 9.0 6.6 7.5 8.8 8.6 19.5 12.0 13.8 15.3 7.8 9.0 14.6 10.7 NAV3 "KIAA0938, POMFIL1" ENSG00000067798 "Neuron navigator 3" Q8IVL0 12 77324641-78213010 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.3;ovary: 18.3" "Group enriched" "Detected in many" 6 "Astrocytes: 882.1;Excitatory neurons: 1473.6;Inhibitory neurons: 753.8;Microglial cells: 534.0;Oligodendrocyte precursor cells: 786.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "amygdala: 9.7;basal ganglia: 15.0;cerebral cortex: 17.3;hippocampal formation: 13.6;white matter: 10.3" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 1.0" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 47.0;THP-1: 41.8;U-138 MG: 30.8;WM-115: 38.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032111, HPA061392" Approved Approved "Nuclear membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear membrane" Cytosol "HPA032111: AB_10603881, HPA061392: " "unprognostic (3.51e-1)" "unprognostic (6.72e-2)" "unprognostic (1.09e-2)" "unprognostic (1.79e-1)" "unprognostic (8.98e-2)" "unprognostic (2.14e-1)" "unprognostic (2.78e-1)" "unprognostic (3.25e-2)" "unprognostic (3.03e-2)" "unprognostic (2.06e-2)" "unprognostic (2.99e-1)" "unprognostic (1.90e-1)" "unprognostic (5.68e-7)" "unprognostic (6.86e-3)" "unprognostic (1.23e-1)" "unprognostic (1.58e-2)" "unprognostic (2.29e-3)" 3.8 4.8 9.7 1.0 15.0 0.5 4.0 0.9 17.3 1.2 0.0 1.7 0.3 2.0 2.9 1.9 2.2 5.1 1.9 13.6 0.0 0.4 1.0 3.3 0.6 0.7 0.4 18.3 0.5 0.4 3.1 2.2 0.0 2.1 0.8 5.2 0.9 2.5 1.3 2.6 0.6 2.5 1.4 8.0 0.8 2.8 1.6 1.9 1.2 3.4 0.4 3.3 1.7 10.3 3.5 8.7 0.6 0.2 8.5 18.1 0.3 26.5 20.9 10.7 5.3 1.7 0.6 0.2 1.9 22.0 7.2 2.5 7.8 4.0 19.3 0.1 0.2 0.2 3.9 0.2 6.7 0.1 0.2 6.2 0.2 47.0 11.1 9.3 16.4 0.1 0.0 0.1 26.2 0.5 0.2 12.0 2.7 0.3 2.1 1.0 2.1 0.0 1.7 0.1 0.6 0.0 1.6 0.3 3.5 0.8 0.1 41.8 14.1 30.8 8.1 12.0 18.2 1.2 0.0 0.7 8.8 0.5 38.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 9.7 15.0 0.9 17.3 13.6 0.0 0.7 0.4 0.0 1.4 1.6 10.3 11.1 19.2 10.0 882.1 0.0 3.6 8.4 0.2 0.0 5.0 3.8 3.8 3.4 0.0 7.5 0.0 0.0 0.1 0.0 0.2 0.0 4.2 10.4 4.2 8.2 5.6 16.4 0.0 1473.6 1.6 0.1 18.7 0.5 10.3 11.4 0.8 3.9 0.0 7.3 50.5 753.8 0.0 0.0 0.0 3.7 4.7 23.9 1.4 12.4 534.0 0.1 18.3 0.0 786.1 144.1 19.2 0.0 7.5 1.2 18.0 0.0 0.3 8.7 2.0 0.0 28.8 5.3 0.3 0.8 0.2 1.4 0.3 1.3 73.7 0.0 2.9 NBEA "BCL8B, FLJ10197, KIAA1544, LYST2" ENSG00000172915 Neurobeachin Q8NFP9 13 34942270-35673022 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 23.5;retina: 65.7" "Group enriched" "Detected in many" 4 "Excitatory neurons: 1016.1;Inhibitory neurons: 953.0;Oligodendrocyte precursor cells: 466.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 33.1;SH-SY5Y: 80.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039730, HPA040385" Enhanced Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "Nucleoplasm, Nucleoli, Cytosol" "HPA039730: AB_10794202, HPA040385: AB_10795523" "unprognostic (1.80e-2)" "unprognostic (2.90e-1)" "unprognostic (4.99e-2)" "unprognostic (3.89e-4)" "unprognostic (3.59e-1)" "unprognostic (2.04e-1)" "unprognostic (8.75e-2)" "unprognostic (6.95e-3)" "unprognostic (5.01e-1)" "unprognostic (7.43e-2)" "unprognostic (1.03e-3)" "unprognostic (2.45e-1)" "prognostic favorable (7.86e-8)" "unprognostic (2.28e-2)" "unprognostic (9.35e-2)" "unprognostic (1.17e-1)" "unprognostic (6.46e-2)" 2.4 7.2 7.7 1.5 10.7 0.3 4.9 19.0 23.5 3.5 2.8 5.8 1.4 6.1 2.2 3.3 5.5 3.4 6.9 17.4 2.8 4.1 0.6 2.0 1.6 4.1 0.1 6.2 3.1 7.1 8.3 0.6 4.8 6.6 2.5 65.7 4.7 8.4 5.6 1.5 2.5 6.5 0.4 3.2 2.7 3.5 0.0 5.6 6.3 5.7 1.2 3.6 2.8 4.5 0.0 4.5 10.9 6.1 0.7 0.1 0.3 7.0 10.8 7.9 6.6 0.1 1.0 3.0 0.0 12.9 4.7 0.3 3.7 1.5 16.3 1.4 3.6 0.0 3.4 1.2 0.5 1.9 4.7 2.1 1.2 0.1 0.7 33.1 1.8 1.2 0.1 17.6 1.1 1.9 1.1 0.0 4.6 6.2 2.0 1.1 4.7 0.9 9.3 2.1 6.2 80.1 5.4 0.1 3.6 8.1 2.0 0.4 0.1 2.0 1.2 0.0 1.6 1.9 0.5 1.3 5.4 0.6 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 7.7 10.7 19.0 23.5 17.4 2.8 4.1 0.1 4.8 0.4 0.0 4.5 19.7 28.9 9.2 132.9 5.2 1.0 5.3 2.7 1.2 124.8 5.0 6.5 51.8 11.5 14.1 9.2 146.0 0.1 4.4 0.3 1.9 9.2 19.3 5.6 18.4 10.1 22.9 0.8 1016.1 1.8 0.1 12.3 2.0 0.6 25.2 20.7 11.0 0.3 0.9 47.1 953.0 2.1 6.1 3.5 3.9 13.6 17.7 3.5 7.2 150.9 1.2 69.1 0.0 466.9 163.7 2.3 0.1 19.2 5.8 8.5 0.2 7.6 56.5 87.0 6.6 22.2 13.1 8.5 8.0 0.3 0.9 0.0 1.2 11.9 1.1 13.5 NCF2 "NOXA2, p67phox" ENSG00000116701 "Neutrophil cytosolic factor 2" P19878 1 183555562-183590876 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 191.9;lung: 74.6;lymphoid tissue: 78.8" "Group enriched" "Detected in many" 5 "Ductal cells: 68.6;Hofbauer cells: 212.0;Kupffer cells: 137.9;Langerhans cells: 129.5;Macrophages: 194.4;monocytes: 223.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1313.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 26.4;HMC-1: 21.4;hTERT-HME1: 51.6;RPMI-8226: 20.0;U-2 OS: 50.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002327, HPA006040, CAB022160" Enhanced Supported Cytosol NA NA 12000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "CAB022160: , HPA002327: AB_1079550, HPA006040: AB_1854906" "unprognostic (4.97e-2)" "unprognostic (3.48e-2)" "unprognostic (2.40e-2)" "unprognostic (1.22e-3)" "unprognostic (5.83e-3)" "unprognostic (4.04e-2)" "prognostic unfavorable (7.91e-6)" "unprognostic (1.29e-1)" "unprognostic (2.45e-1)" "unprognostic (2.33e-1)" "unprognostic (5.70e-2)" "unprognostic (2.01e-1)" "unprognostic (1.57e-2)" "unprognostic (1.61e-1)" "unprognostic (1.41e-2)" "unprognostic (8.24e-2)" "unprognostic (2.36e-2)" 29.9 5.8 2.7 76.9 3.0 191.9 7.0 3.2 14.6 9.5 4.5 10.4 8.5 4.1 1.6 7.6 8.0 23.8 5.6 2.3 3.9 3.7 12.7 74.6 17.3 6.2 4.2 2.1 4.6 2.8 2.7 39.7 6.8 2.9 12.5 0.8 6.6 3.5 3.7 15.9 12.4 20.4 4.5 78.8 5.8 2.1 12.0 11.3 3.0 11.5 16.9 24.2 5.9 7.8 26.4 0.8 0.0 0.0 0.0 0.0 0.3 1.9 2.4 3.4 1.6 0.2 0.8 3.2 4.3 0.8 0.6 14.3 0.1 19.0 3.1 16.2 0.0 0.0 7.3 6.0 0.0 2.0 21.4 0.0 4.1 3.4 51.6 2.2 0.0 0.1 0.0 5.6 5.8 0.2 0.2 1.1 0.4 1.5 1.5 7.0 2.2 20.0 0.8 0.2 0.0 0.1 0.3 0.1 0.9 1.7 2.8 9.1 1.2 0.1 50.2 0.0 4.9 0.9 1.4 0.6 0.4 10.3 0.0 199.5 489.2 1313.6 1.0 348.8 1.6 14.1 4.0 1.6 246.0 10.8 2.2 1.3 799.7 2.1 326.1 13.5 11.1 298.9 2.7 3.0 3.2 14.6 2.3 3.9 6.2 4.2 6.8 4.5 12.0 7.8 0.7 9.6 15.7 0.0 8.4 5.5 0.2 13.7 1.8 0.3 0.1 0.3 1.3 7.2 17.3 0.0 0.0 1.0 9.6 0.1 3.9 68.6 1.1 1.9 0.5 3.5 0.0 1.7 0.3 3.9 1.1 2.0 0.5 1.3 7.6 0.0 3.3 1.0 212.0 0.0 0.3 0.2 26.4 137.9 129.5 2.9 0.6 194.4 7.2 3.7 223.6 0.0 6.2 0.0 0.2 27.3 2.6 0.0 3.2 0.6 0.0 0.3 32.0 0.7 13.1 0.7 6.8 0.1 0.6 0.6 4.3 1.9 3.7 0.2 0.0 1.2 NCKAP1L HEM1 ENSG00000123338 "NCK associated protein 1 like" P55160 12 54497752-54548243 "Plasma proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 44.9" "Cell type enhanced" "Detected in many" "B-cells: 66.2;dendritic cells: 92.3;Hofbauer cells: 115.5;Kupffer cells: 175.1;Macrophages: 108.1;monocytes: 153.2;NK-cells: 113.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HL-60: 112.4;HMC-1: 112.4;NB-4: 82.6;REH: 59.1;THP-1: 121.3;U-937: 70.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039490, HPA040772" Approved Uncertain "Plasma membrane,Cytosol" NA NA 33000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "Plasma membrane" "HPA039490: AB_2676540, HPA040772: AB_2677129" "unprognostic (4.54e-2)" "unprognostic (5.20e-3)" "unprognostic (1.61e-2)" "unprognostic (1.22e-3)" "unprognostic (9.29e-2)" "unprognostic (1.01e-2)" "unprognostic (3.69e-1)" "unprognostic (2.95e-2)" "unprognostic (6.53e-3)" "unprognostic (4.80e-1)" "unprognostic (1.76e-1)" "unprognostic (2.08e-1)" "unprognostic (1.54e-3)" "unprognostic (2.57e-1)" "unprognostic (2.76e-2)" "unprognostic (3.63e-2)" "unprognostic (4.74e-2)" 9.7 4.6 3.3 34.8 4.0 28.4 4.7 3.6 3.7 4.0 4.0 19.7 5.8 2.5 1.3 6.1 3.4 7.3 2.6 2.9 3.7 2.3 7.1 20.2 42.5 6.9 4.8 1.8 1.6 4.0 1.5 11.0 6.5 4.7 9.7 0.4 3.5 5.2 1.2 2.3 18.1 10.3 5.4 44.9 6.7 1.2 6.8 37.4 2.2 2.0 43.4 27.9 2.8 8.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 47.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 40.4 0.3 47.9 0.0 0.0 0.0 112.4 112.4 0.0 0.0 0.0 0.0 0.0 0.7 40.1 7.7 43.7 0.0 0.0 47.9 82.6 0.1 0.0 0.0 59.1 0.2 47.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 121.3 0.0 0.2 0.0 0.1 0.1 2.4 2.9 38.4 0.2 70.4 0.0 31.7 68.6 55.0 31.7 103.9 26.2 30.2 28.3 32.7 72.0 28.8 17.9 26.4 16.9 36.1 121.3 40.8 45.1 65.1 3.3 4.0 3.6 3.7 2.9 3.7 6.9 4.8 6.5 5.4 6.8 8.4 1.0 0.0 11.6 0.3 66.2 1.3 0.3 0.0 0.0 1.3 0.6 2.2 1.5 4.3 1.8 0.0 0.0 0.7 92.3 0.2 0.0 0.1 0.9 0.2 0.3 3.6 0.0 22.1 0.8 0.4 1.0 2.7 2.0 0.3 56.3 0.1 7.5 1.4 115.5 0.0 0.5 0.0 0.0 175.1 28.5 2.3 1.2 108.1 5.4 42.2 153.2 0.4 113.3 0.5 0.0 0.0 0.1 0.0 40.0 0.1 0.0 0.3 0.7 0.9 0.0 0.8 1.3 0.9 1.6 0.1 0.6 1.4 59.7 0.2 0.0 0.2 NCOA4 "ARA70, DKFZp762E1112, ELE1, PTC3, RFG" ENSG00000266412 "Nuclear receptor coactivator 4" Q13772 10 46005088-46030623 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 476.2;Macrophages: 316.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 251.9;granulocytes: 839.6;monocytes: 363.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051260, HPA065208" Uncertain Approved "Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" Nucleoli "Golgi apparatus, Cytosol" "HPA051260: AB_2681412, HPA065208: AB_2685432" "unprognostic (4.23e-2)" "unprognostic (1.50e-1)" "unprognostic (2.44e-2)" "unprognostic (1.82e-1)" "prognostic favorable (3.26e-4)" "unprognostic (1.34e-1)" "unprognostic (1.80e-1)" "unprognostic (9.34e-2)" "unprognostic (4.67e-2)" "unprognostic (5.22e-2)" "unprognostic (9.16e-2)" "unprognostic (2.04e-2)" "prognostic favorable (8.04e-6)" "unprognostic (1.35e-1)" "unprognostic (4.71e-3)" "unprognostic (1.14e-1)" "unprognostic (2.78e-1)" 117.1 67.8 45.6 91.5 52.5 189.5 96.9 56.1 50.9 85.1 50.7 110.3 249.7 70.2 74.6 110.3 62.6 87.8 156.8 40.6 55.8 159.7 372.9 108.3 102.6 52.4 53.5 65.5 64.6 97.9 25.2 131.3 53.6 132.2 115.7 33.7 79.2 78.7 163.5 71.1 155.9 98.3 52.6 148.1 90.3 43.6 51.6 124.4 87.0 193.6 150.3 104.6 46.8 60.0 142.7 58.5 68.0 70.4 176.9 159.4 170.3 128.3 204.8 122.1 119.6 91.0 102.3 161.2 149.2 211.2 69.1 141.8 72.6 142.3 137.1 114.4 74.1 108.4 74.3 263.5 124.0 279.9 229.7 156.1 139.2 104.2 175.7 131.6 185.5 79.5 119.7 93.5 171.9 64.0 136.1 104.3 41.4 110.2 34.8 79.5 99.3 96.7 148.9 119.4 68.2 46.1 128.9 146.2 131.5 133.5 105.7 135.3 171.6 75.8 89.9 81.3 87.5 69.3 79.1 156.9 94.6 231.2 41.2 692.1 363.6 611.8 78.9 223.6 86.2 57.6 73.3 74.9 251.9 53.8 78.2 66.4 839.6 119.0 275.3 77.4 92.8 559.4 45.6 52.5 56.1 50.9 40.6 55.8 52.4 53.5 53.6 52.6 51.6 60.0 44.5 51.3 95.2 13.4 44.6 49.5 39.3 126.2 50.7 14.3 49.6 38.5 161.3 45.8 96.2 44.1 29.2 104.7 58.2 108.8 80.3 45.3 105.4 45.1 37.7 52.9 26.9 476.2 17.4 51.8 107.2 45.3 42.3 56.9 195.2 28.2 55.3 166.7 181.4 20.2 20.5 45.4 59.0 254.5 74.2 72.4 37.3 316.1 51.6 16.9 158.4 38.2 44.3 18.6 22.9 47.8 63.9 47.4 37.6 62.0 162.5 128.8 59.7 13.0 13.1 36.7 46.7 24.5 16.5 71.9 56.7 158.2 41.3 60.7 71.3 52.0 NCOR1 "hCIT529I10, hN-CoR, KIAA1047, MGC104216, N-CoR, PPP1R109, TRAC1" ENSG00000141027 "Nuclear receptor corepressor 1" O75376 17 16029157-16218185 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043246, HPA050288, HPA051168, CAB072830" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "CAB072830: , HPA043246: AB_2678386, HPA050288: AB_2681073, HPA051168: AB_2681370" "unprognostic (1.83e-1)" "unprognostic (3.05e-1)" "unprognostic (9.17e-2)" "unprognostic (1.10e-1)" "unprognostic (7.38e-2)" "unprognostic (3.59e-2)" "unprognostic (2.55e-2)" "unprognostic (4.27e-2)" "unprognostic (4.87e-2)" "unprognostic (4.06e-2)" "unprognostic (7.07e-2)" "unprognostic (1.52e-2)" "prognostic favorable (7.92e-5)" "unprognostic (4.40e-2)" "unprognostic (2.52e-1)" "unprognostic (1.33e-1)" "unprognostic (5.42e-2)" 22.1 18.3 37.8 28.1 39.7 42.8 29.0 60.8 84.7 27.3 41.0 44.0 47.1 30.7 20.3 30.6 25.1 26.4 23.4 39.3 34.7 33.6 46.2 26.9 29.9 32.7 35.7 33.5 34.2 42.3 17.1 28.3 31.0 27.6 40.6 41.4 22.4 31.4 42.0 31.6 38.2 29.7 28.2 29.3 42.7 32.4 35.4 51.9 34.8 39.9 34.7 28.8 18.3 43.4 68.0 110.6 77.7 65.1 62.4 47.1 38.6 48.9 54.8 52.4 47.1 59.8 30.3 70.9 33.6 85.9 39.3 50.4 96.4 59.2 77.3 95.6 71.1 70.7 96.3 71.1 60.8 45.3 80.7 48.5 60.6 81.2 94.4 45.2 73.9 98.0 63.0 28.8 52.3 44.3 79.3 29.1 38.6 118.6 29.9 78.1 78.5 33.5 54.9 76.0 26.5 43.8 80.7 34.7 37.7 197.5 33.5 50.3 65.5 53.7 32.6 39.9 68.3 19.7 25.0 40.4 51.0 52.4 47.0 408.4 104.8 240.4 126.9 86.0 106.7 188.4 144.0 141.0 76.3 191.4 139.8 139.0 205.2 139.9 112.3 130.3 144.7 98.8 37.8 39.7 60.8 84.7 39.3 34.7 32.7 35.7 31.0 28.2 35.4 43.4 90.9 80.1 113.2 116.2 130.0 67.8 106.2 91.3 86.0 150.3 76.8 60.8 91.5 82.9 86.9 53.3 158.4 102.1 121.7 198.1 35.2 95.5 69.7 75.7 109.5 88.4 87.9 132.1 127.0 96.5 101.7 77.1 149.4 103.7 87.3 88.9 67.5 126.4 76.1 129.5 122.2 118.8 81.4 81.9 76.7 43.6 101.5 96.7 37.4 107.7 172.8 83.1 197.8 123.1 151.4 111.7 148.3 121.5 88.5 95.6 194.4 46.7 63.8 167.1 92.1 106.0 106.2 98.7 90.2 78.0 68.2 87.6 142.1 89.5 153.0 122.9 NDE1 "FLJ20101, NDE, nudE" ENSG00000072864 "NudE neurodevelopment protein 1" Q9NXR1 16 15643267-15734691 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis" "Developmental protein" Lissencephaly "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 105.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "granulocytes: 21.8;monocytes: 11.7;NK-cells: 8.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024075 Approved NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" "HPA024075: AB_1854336" "unprognostic (1.09e-1)" "unprognostic (1.66e-1)" "unprognostic (3.26e-1)" "unprognostic (1.47e-1)" "unprognostic (3.84e-1)" "unprognostic (4.11e-2)" "prognostic unfavorable (9.92e-4)" "unprognostic (1.43e-2)" "unprognostic (1.59e-1)" "unprognostic (4.55e-2)" "unprognostic (3.70e-3)" "unprognostic (1.16e-1)" "prognostic unfavorable (8.19e-4)" "unprognostic (1.29e-1)" "unprognostic (3.28e-2)" "unprognostic (2.22e-1)" "unprognostic (2.93e-2)" 9.2 5.8 12.1 13.0 23.6 25.6 9.4 22.5 15.6 14.6 6.9 25.0 7.5 11.6 2.6 17.7 11.1 9.8 10.6 11.2 16.1 6.3 4.2 11.1 20.4 30.0 24.5 7.5 4.0 4.0 3.1 10.0 26.5 14.2 7.3 2.0 12.2 5.1 7.3 27.6 12.9 10.7 17.0 12.5 10.1 11.1 21.3 23.4 6.3 7.9 20.9 15.3 19.8 43.2 37.0 33.0 34.2 39.9 11.4 18.6 10.4 15.4 21.0 30.4 34.5 18.3 58.3 21.9 24.0 23.2 16.7 34.5 25.3 47.3 20.8 33.7 16.0 24.6 35.3 51.7 16.3 33.3 37.2 6.6 28.9 28.8 52.0 16.9 40.6 27.9 20.5 80.5 26.6 43.9 43.0 30.5 30.5 26.5 14.3 64.8 32.3 34.8 11.6 24.1 17.0 21.0 27.5 40.7 27.6 25.9 42.8 34.3 12.5 26.9 17.6 43.2 36.1 17.4 13.1 38.1 27.5 43.0 55.0 5.1 4.7 15.0 3.0 3.8 1.7 3.3 3.0 1.3 3.4 1.9 1.8 2.0 21.8 8.5 11.7 3.1 3.3 3.9 12.1 23.6 22.5 15.6 11.2 16.1 30.0 24.5 26.5 17.0 21.3 43.2 11.7 3.2 4.4 11.1 36.1 26.0 32.7 19.0 24.5 7.0 9.5 10.4 2.0 4.3 8.9 5.5 6.2 3.9 25.0 9.6 0.0 4.5 46.9 17.1 23.1 11.6 4.2 49.0 2.1 5.3 5.3 11.8 19.4 15.0 10.8 15.5 8.6 1.7 10.1 3.3 2.4 7.4 2.0 15.8 11.0 58.5 15.8 19.3 12.4 22.5 53.0 7.4 50.4 9.5 105.5 7.1 4.2 6.0 16.6 26.3 4.6 1.9 13.3 6.5 6.6 6.9 9.5 13.8 10.0 18.8 30.7 2.5 28.3 9.8 10.2 21.6 NDFIP1 "MGC10924, N4WBP5" ENSG00000131507 "Nedd4 family interacting protein 1" Q9BT67 5 142108779-142154440 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Theca cells: 678.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009682 Approved "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA009682: AB_1079455" "unprognostic (2.78e-2)" "unprognostic (1.62e-1)" "unprognostic (9.26e-2)" "unprognostic (5.66e-3)" "unprognostic (4.74e-2)" "prognostic unfavorable (2.33e-7)" "unprognostic (6.95e-2)" "unprognostic (4.96e-2)" "unprognostic (5.97e-2)" "unprognostic (1.74e-2)" "unprognostic (3.28e-1)" "unprognostic (4.46e-2)" "prognostic favorable (2.39e-7)" "unprognostic (9.18e-2)" "unprognostic (2.06e-1)" "unprognostic (6.23e-2)" "unprognostic (8.76e-2)" 62.1 81.6 87.4 33.8 93.8 26.2 56.3 63.1 100.7 54.7 70.8 40.3 49.3 45.2 135.9 30.2 46.4 45.4 55.1 94.2 96.8 94.8 120.2 49.7 39.0 70.7 73.6 61.5 64.5 152.6 51.7 45.2 77.2 67.7 38.4 164.1 99.5 63.5 45.7 26.6 47.6 40.9 75.3 56.4 50.4 40.8 90.8 41.9 103.4 40.9 34.8 48.3 31.1 73.9 53.3 35.2 61.8 83.6 128.2 72.5 41.4 56.6 59.1 48.0 54.6 39.5 87.3 4.8 115.0 62.2 66.4 51.9 39.6 59.6 56.2 61.2 48.8 69.2 30.8 28.7 55.8 38.3 23.9 55.8 55.3 33.8 43.6 68.4 55.9 54.0 23.4 83.3 60.1 27.4 42.9 12.0 33.2 52.0 33.4 16.1 34.2 122.1 119.1 56.0 65.0 67.3 61.9 91.7 88.3 46.0 64.7 37.6 64.5 58.7 22.1 48.0 56.8 53.6 65.8 22.0 62.1 24.9 45.6 70.4 32.1 26.4 22.9 39.9 29.2 12.8 40.6 28.2 37.0 10.4 80.9 63.9 19.5 23.5 40.1 11.2 50.6 62.4 87.4 93.8 63.1 100.7 94.2 96.8 70.7 73.6 77.2 75.3 90.8 73.9 100.3 57.7 62.6 74.7 76.4 111.5 176.4 133.4 82.0 196.4 134.3 68.5 70.0 143.0 101.4 154.5 141.8 146.9 94.0 98.0 140.8 207.4 20.2 69.5 91.5 103.7 137.6 184.9 189.5 145.3 263.8 164.1 62.7 118.2 60.2 365.2 116.0 169.8 154.1 318.0 184.9 81.9 177.0 205.9 154.9 15.4 116.5 137.0 170.7 69.3 176.1 300.6 87.6 114.1 125.4 179.8 100.5 156.9 107.6 262.6 198.5 173.0 67.7 322.9 131.5 74.3 149.3 26.6 33.2 71.1 101.3 191.5 156.4 678.1 83.3 256.2 NDN "HsT16328, PWCR" ENSG00000182636 "Necdin, MAGE family member" Q99608 15 23685400-23687305 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Growth regulation, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 236.4;Peritubular cells: 207.6;Theca cells: 121.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.5" "Cell line enhanced" "Detected in many" "AF22: 55.0;ASC diff: 52.9;HSkMC: 71.3;NTERA-2: 44.0;SuSa: 57.4;U-2 OS: 80.4;U-266/70: 51.7;U-266/84: 51.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074457 Approved Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA074457: AB_2686691" "unprognostic (3.49e-1)" "unprognostic (1.65e-1)" "unprognostic (4.20e-1)" "unprognostic (2.19e-2)" "unprognostic (2.71e-1)" "unprognostic (9.04e-2)" "unprognostic (6.79e-2)" "unprognostic (3.51e-1)" "unprognostic (3.11e-2)" "unprognostic (1.57e-1)" "unprognostic (1.03e-2)" "unprognostic (4.05e-2)" "prognostic unfavorable (4.52e-4)" "unprognostic (1.89e-2)" "unprognostic (8.10e-2)" "unprognostic (1.96e-1)" "unprognostic (6.81e-2)" 46.8 49.4 43.3 11.1 40.5 1.2 35.1 26.0 39.7 70.5 30.4 35.9 11.1 63.7 24.0 16.8 47.2 23.8 34.6 36.7 89.6 13.0 4.5 19.6 10.9 36.0 41.3 69.8 11.8 8.7 56.3 32.6 46.2 27.3 10.7 20.8 12.7 39.3 14.7 11.9 20.8 33.5 36.7 19.1 20.3 18.5 69.6 6.8 17.4 22.4 6.6 31.4 40.4 32.3 0.1 0.0 55.0 0.0 52.9 20.1 0.1 35.4 0.0 0.8 9.6 0.0 0.0 0.0 0.1 10.6 8.2 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 13.3 0.0 31.8 71.3 0.0 10.2 0.0 0.0 0.0 21.7 1.2 0.0 18.0 0.0 27.6 0.1 44.0 0.0 0.0 0.0 0.0 0.1 3.8 0.0 0.1 0.4 0.0 0.4 0.0 57.4 9.4 0.0 0.0 2.6 80.4 0.0 0.1 51.7 51.7 0.0 5.5 0.0 0.4 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.2 1.5 0.0 0.0 43.3 40.5 26.0 39.7 36.7 89.6 36.0 41.3 46.2 36.7 69.6 32.3 24.1 25.6 11.0 6.8 0.3 13.0 13.8 0.3 27.9 66.0 2.3 19.8 36.8 15.7 1.4 12.9 20.9 1.9 2.9 18.5 23.5 17.9 2.5 1.4 60.8 18.7 6.7 4.2 7.8 10.7 1.4 103.1 4.1 1.1 0.0 83.9 38.9 0.2 7.3 50.5 21.8 4.3 0.0 7.6 13.3 8.6 236.4 2.8 39.2 9.4 0.7 88.7 0.0 9.5 16.4 4.5 2.6 207.6 0.0 6.9 8.1 1.1 4.1 51.0 98.6 91.4 94.0 28.5 21.8 13.4 8.2 2.5 1.4 121.8 7.1 4.1 NDNF "C4orf31, FLJ23191" ENSG00000173376 "Neuron derived neurotrophic factor" Q8TB73 4 121035613-121073021 "Disease related genes, Predicted secreted proteins" Neurogenesis "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 106.5;placenta: 60.1;retina: 57.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 246.8;Bipolar cells: 69.8;Early spermatids: 217.1;Late spermatids: 221.7" "Cancer enriched" "Detected in many" 4 "lung cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 48.5;U-266/70: 20.8;U-266/84: 85.8" "Group enriched" "Detected in all" 4 "basal ganglia: 11.1;olfactory bulb: 34.0" "Low region specificity" "Detected in all" HPA048881 Supported Vesicles "Secreted in other tissues" NA NA "Cluster 19: Lung - Lung function" "Cluster 16: U-266 - Nucleosome" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA048881: " "unprognostic (2.84e-1)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (1.04e-1)" "unprognostic (3.94e-1)" "unprognostic (6.26e-2)" "unprognostic (2.22e-1)" "unprognostic (2.93e-2)" "unprognostic (6.65e-4)" "unprognostic (2.18e-3)" "unprognostic (6.27e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (3.26e-4)" "unprognostic (2.38e-3)" "unprognostic (1.20e-1)" "unprognostic (1.18e-4)" "unprognostic (1.74e-1)" 4.8 2.6 1.1 0.9 1.7 0.0 3.2 4.7 1.2 14.2 9.3 6.5 2.9 6.0 4.3 7.7 20.4 9.4 5.2 1.8 2.6 27.1 0.4 106.5 0.3 8.8 12.9 42.5 0.5 0.7 5.3 60.1 15.2 16.7 8.3 57.4 2.2 4.4 4.3 1.7 4.7 3.5 7.6 0.3 4.1 10.4 3.7 2.4 1.3 14.0 0.2 9.0 1.9 5.4 0.2 0.0 10.6 0.0 13.9 11.3 0.2 0.2 0.5 0.2 0.5 1.6 0.0 0.0 0.0 48.5 0.8 0.0 0.0 0.0 1.1 0.9 1.7 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.2 0.6 0.0 0.0 0.0 14.3 1.0 0.0 0.2 0.1 0.9 7.4 2.1 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.0 2.6 0.2 0.0 0.0 11.5 0.0 0.2 0.5 20.8 85.8 0.0 3.9 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.7 4.7 1.2 1.8 2.6 8.8 12.9 15.2 7.6 3.7 5.4 10.9 246.8 48.3 1.6 0.0 1.1 0.0 0.0 0.0 69.8 0.2 0.1 1.6 8.6 28.6 12.9 18.8 0.3 0.0 5.3 0.0 0.0 217.1 0.9 4.7 11.7 1.8 0.0 0.0 0.2 0.0 14.9 0.0 0.1 2.5 0.1 2.9 0.0 0.1 1.7 8.0 0.8 0.0 0.0 0.8 221.7 3.4 0.4 5.4 6.5 0.0 12.2 0.0 0.0 0.0 0.1 0.5 0.7 0.0 0.0 0.0 0.0 12.5 20.0 0.0 1.2 3.6 6.4 5.0 0.3 0.9 0.5 0.3 13.0 1.2 0.1 NDUFB11 "ESSS, Np15, NP17.3" ENSG00000147123 "NADH:ubiquinone oxidoreductase subunit B11" Q9NX14 X 47142216-47145038 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Cardiomyopathy, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 717.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030367 Supported Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA030367: AB_10603882" "unprognostic (2.20e-1)" "unprognostic (6.77e-3)" "unprognostic (1.39e-1)" "unprognostic (1.33e-1)" "unprognostic (9.80e-2)" "unprognostic (8.84e-2)" "unprognostic (3.31e-2)" "unprognostic (2.05e-1)" "unprognostic (5.18e-2)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "unprognostic (2.19e-1)" "unprognostic (6.58e-2)" "unprognostic (3.27e-1)" "unprognostic (2.34e-1)" "unprognostic (1.69e-1)" "unprognostic (8.46e-3)" 71.1 133.8 136.0 73.2 141.2 133.2 89.8 147.7 170.6 74.6 158.5 112.5 96.7 54.4 104.6 95.2 84.1 46.2 251.4 140.3 142.3 108.9 164.4 62.2 90.3 144.7 139.0 58.5 158.2 122.9 92.7 62.4 142.0 73.9 98.2 59.2 128.2 79.2 717.0 76.1 96.1 72.2 138.3 74.5 97.8 26.8 146.3 97.8 95.6 378.4 106.3 68.0 66.5 139.3 173.5 297.9 198.7 242.4 173.6 166.1 221.1 125.2 180.5 231.5 224.4 292.6 224.2 218.5 101.8 163.4 222.3 216.2 267.0 157.3 162.0 212.4 663.1 129.5 371.2 271.3 184.7 203.2 188.2 176.9 140.0 191.2 126.8 137.8 193.9 286.8 158.6 282.6 139.3 437.2 269.1 622.5 308.5 219.2 517.2 259.7 210.9 513.6 254.0 210.1 391.2 283.1 231.9 289.2 198.8 259.8 418.2 279.7 130.3 152.7 190.5 239.1 149.0 244.0 270.0 258.5 155.0 138.4 204.2 255.4 410.3 188.6 294.2 306.5 362.1 541.7 408.9 342.6 491.6 470.0 454.3 359.3 84.9 279.7 233.8 636.5 476.3 626.1 136.0 141.2 147.7 170.6 140.3 142.3 144.7 139.0 142.0 138.3 146.3 139.3 154.0 105.8 132.5 16.6 270.9 259.5 252.1 514.5 267.5 89.2 343.7 520.1 236.6 265.9 284.7 290.6 37.5 456.9 227.6 400.0 583.0 314.9 5.2 193.4 229.7 165.6 330.7 246.3 10.2 369.1 429.2 192.1 200.8 267.1 194.1 219.2 203.8 657.2 391.0 55.5 16.7 495.1 333.7 321.7 290.9 16.3 181.7 229.1 265.1 12.2 336.9 238.9 183.4 14.1 25.3 291.8 391.2 176.4 445.1 258.6 360.1 756.8 180.9 109.8 164.3 157.6 248.9 16.8 36.9 358.0 290.5 450.9 228.9 342.6 447.4 334.9 NDUFC2 "B14.5b, HLC-1" ENSG00000151366 "NADH:ubiquinone oxidoreductase subunit C2" O95298 11 78068297-78079862 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA038873, HPA056195" Approved Supported Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA038873: AB_10673480, HPA056195: AB_2683063" "unprognostic (7.32e-2)" "unprognostic (5.91e-3)" "unprognostic (4.00e-2)" "unprognostic (6.14e-2)" "unprognostic (1.94e-1)" "unprognostic (8.97e-2)" "unprognostic (1.60e-1)" "unprognostic (4.23e-3)" "unprognostic (4.75e-3)" "unprognostic (3.32e-3)" "unprognostic (1.34e-1)" "unprognostic (2.11e-1)" "prognostic favorable (5.00e-5)" "unprognostic (6.32e-2)" "unprognostic (3.01e-1)" "unprognostic (4.18e-2)" "unprognostic (3.61e-3)" 202.3 278.0 118.8 84.5 126.1 126.1 143.0 128.7 150.7 103.0 125.6 143.6 218.4 125.3 68.4 142.6 120.2 108.6 240.7 129.0 145.8 151.1 286.8 100.0 109.1 121.6 117.1 96.2 168.8 186.1 133.5 74.8 124.2 88.7 66.1 59.8 275.1 83.2 487.6 121.9 194.3 63.6 136.8 96.2 130.0 103.0 126.1 73.5 207.0 254.0 62.8 97.1 100.1 136.3 287.6 342.2 183.3 118.8 168.3 105.6 227.2 335.7 190.9 252.4 179.9 910.4 311.8 166.3 583.3 155.8 210.2 293.1 136.1 190.9 99.5 318.8 386.7 183.8 337.4 727.9 270.9 409.7 164.2 147.9 177.8 195.6 75.2 156.0 172.9 158.8 365.3 278.4 137.9 478.7 254.5 722.4 212.4 670.4 415.6 224.5 352.5 570.5 196.4 420.7 261.2 229.0 235.0 499.5 182.3 158.8 391.4 328.2 241.0 256.4 314.9 611.8 297.9 251.5 541.9 400.4 146.4 236.6 251.0 374.5 337.6 354.0 150.1 293.0 138.3 230.8 172.4 163.4 363.5 212.1 144.5 159.8 102.2 225.4 243.0 290.4 202.7 410.9 118.8 126.1 128.7 150.7 129.0 145.8 121.6 117.1 124.2 136.8 126.1 136.3 256.6 166.7 194.7 0.0 106.4 95.5 166.1 443.7 40.5 145.8 346.2 414.0 240.9 243.1 288.2 391.8 66.7 408.8 166.4 206.3 305.2 395.6 311.8 413.8 129.3 183.7 167.9 106.5 0.0 431.5 392.8 165.7 43.3 241.7 153.2 158.1 184.9 856.9 346.2 90.9 0.0 317.9 429.3 174.5 110.7 84.7 215.6 129.4 245.5 0.0 246.7 310.0 175.1 0.0 0.0 456.5 329.1 201.6 102.5 239.0 461.8 454.6 300.0 131.6 236.7 154.5 222.7 384.4 162.1 67.5 114.4 387.1 109.9 226.3 373.2 215.6 NDUFS1 CI-75k ENSG00000023228 "NADH:ubiquinone oxidoreductase core subunit S1" P28331 2 206114817-206159509 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 181.7;skeletal muscle: 221.6;tongue: 225.2" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 582.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064605, CAB070844" Enhanced Supported Mitochondria NA NA 48000 "Cluster 14: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB070844: , HPA064605: AB_2685297" "prognostic unfavorable (3.85e-4)" "unprognostic (1.76e-1)" "unprognostic (9.22e-3)" "unprognostic (5.01e-2)" "unprognostic (8.63e-3)" "unprognostic (3.75e-1)" "unprognostic (3.72e-2)" "unprognostic (6.18e-2)" "unprognostic (2.30e-2)" "unprognostic (3.28e-1)" "unprognostic (2.00e-2)" "unprognostic (1.28e-1)" "prognostic favorable (1.47e-12)" "unprognostic (1.17e-1)" "unprognostic (1.29e-1)" "unprognostic (4.76e-2)" "unprognostic (4.73e-2)" 27.1 61.6 8.3 13.3 10.8 13.2 23.8 14.9 16.1 19.5 39.7 35.3 29.9 19.3 10.8 36.2 16.3 10.5 181.7 10.7 13.7 48.0 51.8 18.3 12.6 10.1 10.1 14.6 19.2 47.2 20.2 14.4 11.7 15.8 30.0 24.4 27.7 15.6 221.6 26.6 26.1 16.4 9.2 16.8 37.1 20.8 14.2 15.6 17.9 225.2 16.9 22.4 22.4 12.5 28.3 27.6 39.2 28.6 35.8 28.9 45.4 40.4 43.4 66.0 47.6 72.0 32.1 31.7 34.8 50.8 65.5 38.5 52.9 39.2 58.2 14.6 24.9 63.5 65.1 64.9 37.0 46.2 27.5 35.3 22.5 51.9 40.4 29.6 52.3 39.3 69.8 31.1 43.6 35.2 38.5 30.7 36.5 47.2 48.6 38.3 54.7 55.1 54.7 50.7 38.1 29.8 46.7 45.1 67.1 53.3 39.8 44.2 40.1 36.2 32.0 35.8 39.1 29.8 38.4 46.9 36.3 37.5 37.8 14.1 12.9 15.7 12.4 15.2 9.6 9.6 10.8 11.8 14.7 9.0 9.6 11.1 9.2 12.5 22.5 7.8 15.9 9.5 8.3 10.8 14.9 16.1 10.7 13.7 10.1 10.1 11.7 9.2 14.2 12.5 32.4 60.9 33.0 45.1 23.8 16.2 21.7 40.8 30.1 97.1 19.3 14.0 582.5 48.6 42.8 38.6 120.9 48.4 18.8 74.5 93.9 44.2 14.5 49.8 49.8 36.6 51.0 42.0 67.8 28.2 33.7 42.3 48.4 54.5 37.3 42.3 29.3 94.5 34.0 117.8 72.8 47.9 54.9 31.2 10.7 7.0 33.5 27.7 30.2 28.1 37.2 62.7 27.8 45.2 41.6 32.1 46.4 44.8 31.0 19.9 77.8 102.3 53.5 81.5 32.9 55.2 60.8 58.2 49.5 40.8 16.6 52.5 23.7 71.5 69.9 26.6 NDUFS2 CI-49 ENSG00000158864 "NADH:ubiquinone oxidoreductase core subunit S2" O75306 1 161197104-161214723 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 464.8;tongue: 633.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055140, HPA061953" Enhanced Supported Mitochondria NA NA 25000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA055140: AB_2682713, HPA061953: AB_2684646" "unprognostic (2.13e-2)" "unprognostic (2.24e-2)" "unprognostic (8.47e-2)" "unprognostic (7.78e-2)" "unprognostic (9.81e-2)" "unprognostic (2.70e-1)" "unprognostic (1.10e-2)" "unprognostic (1.51e-1)" "unprognostic (3.10e-1)" "unprognostic (1.57e-2)" "unprognostic (3.17e-2)" "unprognostic (1.11e-1)" "prognostic favorable (2.32e-4)" "unprognostic (2.35e-1)" "unprognostic (2.80e-1)" "unprognostic (1.13e-1)" "unprognostic (1.82e-1)" 60.2 98.2 38.7 37.4 41.6 39.5 49.6 46.4 48.8 40.2 76.6 96.5 102.4 41.4 33.4 62.0 52.5 36.8 273.7 40.5 47.5 137.0 177.4 48.5 42.4 49.5 40.7 51.6 47.7 156.5 35.8 41.6 53.1 45.7 101.8 36.2 53.5 49.0 464.8 51.4 81.5 58.6 41.6 43.6 73.3 29.5 47.9 48.3 45.0 633.7 60.1 57.5 40.0 49.2 101.8 129.4 95.2 104.0 115.1 102.8 77.0 85.7 105.8 139.6 107.5 143.9 98.5 108.4 168.1 113.0 81.3 135.9 129.1 131.8 122.1 84.2 108.0 105.9 109.5 136.5 117.7 116.0 105.3 147.2 112.3 121.1 137.2 96.8 160.5 115.4 139.9 72.7 132.5 93.5 81.7 58.4 175.3 288.5 116.5 72.0 83.3 172.0 157.8 109.4 97.2 152.0 93.0 237.0 151.5 116.4 221.7 342.2 108.6 84.5 66.3 65.5 123.7 125.2 172.0 95.1 123.6 109.3 105.4 150.0 159.3 85.7 82.0 193.2 82.6 81.4 86.6 86.3 217.8 68.4 86.6 88.1 86.7 93.5 190.7 128.7 130.8 167.5 38.7 41.6 46.4 48.8 40.5 47.5 49.5 40.7 53.1 41.6 47.9 49.2 70.5 35.3 45.7 30.7 47.1 38.9 52.4 277.8 52.9 74.6 58.9 50.7 232.6 74.4 148.4 77.3 31.3 146.8 47.6 187.5 332.6 184.3 11.3 43.5 57.0 67.5 72.0 78.9 28.0 143.2 111.3 69.7 80.5 41.3 69.7 99.7 65.7 206.5 150.5 92.5 30.1 122.6 242.1 87.8 42.0 7.8 43.5 66.5 83.6 14.0 97.9 57.0 35.0 18.1 48.3 147.7 105.1 33.4 49.5 25.6 221.9 345.5 103.0 57.3 46.0 41.9 176.6 42.0 27.5 68.8 43.3 158.4 50.0 192.0 172.5 57.5 NDUFS4 "AQDQ, CI-18" ENSG00000164258 "NADH:ubiquinone oxidoreductase subunit S4" O43181 5 53560633-53683338 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 397.4" "Cell type enhanced" "Detected in all" "Distal tubular cells: 553.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003884 Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA003884: AB_1079465" "unprognostic (1.25e-1)" "unprognostic (3.61e-3)" "unprognostic (3.44e-2)" "unprognostic (8.11e-2)" "unprognostic (1.46e-1)" "unprognostic (6.73e-3)" "unprognostic (6.93e-2)" "unprognostic (1.11e-1)" "unprognostic (3.93e-1)" "unprognostic (4.38e-1)" "unprognostic (1.72e-2)" "unprognostic (3.11e-1)" "prognostic favorable (3.85e-6)" "unprognostic (9.19e-2)" "unprognostic (1.24e-1)" "unprognostic (1.65e-1)" "unprognostic (1.81e-1)" 94.2 80.6 71.3 37.0 71.8 50.9 99.9 75.1 101.8 82.0 70.6 93.2 83.6 65.0 68.6 80.6 69.5 50.2 190.5 70.3 78.3 137.2 147.9 55.7 45.7 72.3 70.4 101.7 45.4 125.8 58.2 63.0 73.8 65.9 89.6 59.1 63.6 73.6 346.2 76.7 71.9 72.2 75.3 42.9 80.7 37.9 75.1 59.8 74.0 397.4 60.7 71.3 73.0 77.7 118.8 102.9 200.5 119.1 133.9 192.7 167.9 140.7 136.6 153.0 185.8 126.7 151.4 83.9 180.2 121.1 146.3 85.3 72.0 167.9 175.4 77.4 137.2 57.8 97.1 115.6 142.4 141.0 95.8 161.2 190.2 105.8 184.8 167.7 135.1 93.4 50.2 88.5 141.9 110.5 106.7 116.9 60.9 45.3 115.1 126.4 113.1 166.2 165.1 113.0 92.7 99.5 96.4 92.5 175.2 106.8 148.2 145.2 104.4 93.6 98.9 68.7 186.9 67.6 91.5 102.1 99.7 202.7 137.3 19.4 83.9 7.9 49.1 101.8 55.3 72.7 61.9 58.0 121.6 50.3 68.2 70.0 6.8 79.4 108.3 93.8 72.4 68.2 71.3 71.8 75.1 101.8 70.3 78.3 72.3 70.4 73.8 75.3 75.1 77.7 62.1 38.5 56.6 49.0 52.6 125.8 150.4 382.0 56.3 44.8 100.0 119.1 328.4 82.9 170.6 84.6 41.7 168.4 43.2 124.5 553.7 174.1 61.5 65.5 87.7 84.6 90.4 47.1 55.9 167.3 163.3 113.1 47.9 68.7 76.0 146.9 99.2 137.8 144.3 30.3 73.2 135.3 215.7 76.4 127.3 61.5 157.5 70.4 117.4 38.4 161.4 113.6 63.8 52.8 68.4 179.4 153.4 152.7 38.4 95.3 188.7 425.9 112.2 76.0 124.9 145.1 173.4 76.8 75.0 79.3 101.4 179.9 50.0 96.4 171.2 158.2 NDUFV1 CI-51K ENSG00000167792 "NADH:ubiquinone oxidoreductase core subunit V1" P49821 11 67605653-67612554 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 526.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 482.4;Proximal tubular cells: 499.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045211, HPA075051" Enhanced Supported Mitochondria,Cytosol No No 37000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA045211: AB_10962830, HPA075051: AB_2686732" "unprognostic (4.57e-2)" "unprognostic (2.17e-2)" "unprognostic (2.84e-1)" "unprognostic (7.07e-2)" "unprognostic (1.54e-1)" "unprognostic (4.54e-3)" "unprognostic (1.19e-1)" "unprognostic (3.31e-2)" "unprognostic (2.19e-1)" "unprognostic (4.95e-2)" "unprognostic (4.02e-2)" "unprognostic (3.03e-2)" "prognostic favorable (7.49e-10)" "unprognostic (1.12e-2)" "unprognostic (1.80e-1)" "unprognostic (2.12e-1)" "unprognostic (1.16e-1)" 95.0 126.5 87.6 52.5 93.7 72.5 90.9 105.6 107.1 93.9 104.8 142.3 124.5 85.2 33.8 114.0 84.6 47.1 400.2 91.6 97.0 188.4 187.0 77.1 66.7 103.3 91.5 101.9 117.2 169.8 84.5 46.7 110.4 77.4 73.7 81.6 90.2 73.2 526.2 117.7 96.6 51.1 86.9 98.8 132.0 76.0 104.9 51.6 107.6 440.5 62.8 88.1 88.6 99.9 132.9 133.6 68.8 141.3 85.6 83.4 130.6 84.1 76.4 122.2 82.6 256.8 155.3 241.9 167.3 69.2 99.7 176.8 146.1 126.4 38.4 125.2 114.9 100.0 189.1 127.9 119.0 136.9 106.9 126.7 119.0 100.4 88.0 76.9 109.3 173.9 180.9 192.6 75.8 190.2 163.1 268.0 68.5 295.3 168.8 184.5 135.8 399.1 99.3 95.3 109.9 104.6 104.3 347.4 275.3 46.0 177.4 138.0 90.7 118.9 88.8 172.3 87.5 187.7 116.8 122.6 138.0 144.6 117.7 39.0 72.8 38.1 65.1 83.4 71.6 59.8 55.0 63.2 110.7 60.1 50.2 63.7 13.1 104.0 51.2 73.0 78.1 77.0 87.6 93.7 105.6 107.1 91.6 97.0 103.3 91.5 110.4 86.9 104.9 99.9 54.6 60.9 75.0 33.3 76.2 80.3 95.9 187.6 77.4 68.7 82.1 94.4 482.4 61.5 120.7 86.5 50.1 203.5 72.8 235.7 397.2 114.9 74.0 43.1 47.5 56.7 98.5 85.0 32.9 112.1 158.8 82.4 137.1 55.2 61.4 99.6 56.4 136.2 136.5 63.9 36.5 155.9 152.5 68.8 81.4 222.7 65.6 68.4 113.8 13.1 81.0 89.3 60.8 19.1 34.6 70.1 122.8 59.0 146.6 55.0 199.4 499.2 80.3 78.5 46.0 90.8 136.9 100.7 83.3 127.0 80.6 189.1 79.3 145.9 274.8 111.7 NECAB2 EFCBP2 ENSG00000103154 "N-terminal EF-hand calcium binding protein 2" Q7Z6G3 16 83968244-84002776 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 106.4" "Cell type enhanced" "Detected in some" "Early spermatids: 16.6;Hepatocytes: 10.7;Inhibitory neurons: 22.2;Late spermatids: 49.2;Muller glia cells: 17.8;Proximal tubular cells: 27.8" "Cancer enhanced" "Detected in many" "liver cancer: 7.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 66 "neutrophil: 55.4" "Lineage enriched" "Detected in single" 66 "granulocytes: 55.4" "Cell line enhanced" "Detected in some" "AF22: 10.1;MCF7: 6.8;SCLC-21H: 37.6;U-87 MG: 12.2" "Low region specificity" "Detected in all" "HPA013998, HPA014144, CAB068211" Enhanced Supported NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB068211: AB_2665678, HPA013998: AB_1848016, HPA014144: AB_1848017" "unprognostic (5.27e-2)" "unprognostic (1.14e-1)" "unprognostic (5.50e-2)" "unprognostic (3.48e-5)" "unprognostic (3.45e-2)" "unprognostic (4.20e-2)" "unprognostic (6.74e-2)" "unprognostic (8.79e-2)" "unprognostic (4.15e-1)" "unprognostic (2.59e-1)" "unprognostic (5.75e-3)" "unprognostic (2.14e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (8.89e-3)" "unprognostic (3.48e-1)" "unprognostic (8.61e-3)" "unprognostic (3.75e-2)" 0.9 0.5 67.8 0.6 73.0 0.5 0.7 20.3 106.4 2.0 24.9 1.3 1.2 1.2 0.3 0.1 0.4 0.5 1.2 80.5 62.0 11.1 26.0 0.5 0.2 32.1 50.7 0.5 1.9 6.7 16.2 0.3 80.2 0.3 0.2 3.1 0.1 0.1 0.2 0.2 1.2 0.4 24.9 1.6 1.8 10.5 59.4 0.2 0.5 0.2 0.0 0.3 0.2 31.4 0.2 4.4 10.1 0.0 0.0 1.4 0.1 0.1 0.2 0.1 0.1 0.3 0.2 0.0 1.6 0.2 0.8 0.0 1.9 0.0 0.0 0.1 2.9 0.0 0.0 0.5 0.1 0.0 1.7 0.5 0.2 0.3 0.1 0.2 0.1 0.0 0.2 0.1 0.0 6.8 0.0 0.0 5.0 0.4 0.6 0.1 0.0 0.6 0.0 0.0 37.6 1.5 0.0 0.2 3.1 1.4 5.2 1.4 0.3 0.2 2.8 0.4 0.0 0.1 0.0 0.0 12.2 0.5 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.4 0.0 0.0 0.0 0.0 0.1 67.8 73.0 20.3 106.4 80.5 62.0 32.1 50.7 80.2 24.9 59.4 31.4 0.1 0.0 0.0 4.6 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.0 16.6 0.0 0.1 0.1 7.2 0.0 2.2 0.0 0.0 0.3 0.0 0.1 0.0 0.6 0.0 10.7 3.4 0.0 22.2 0.0 0.0 0.0 0.0 49.2 0.3 0.3 0.0 3.7 0.2 17.8 0.0 4.0 0.6 0.0 0.0 0.7 0.0 0.0 0.3 27.8 0.0 0.3 0.0 0.1 0.0 2.1 3.3 0.0 0.0 0.0 0.1 0.3 0.0 0.0 NETO2 "FLJ10430, NEOT2" ENSG00000171208 "Neuropilin and tolloid like 2" Q8NC67 16 47077703-47143945 "Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.8;lymphoid tissue: 22.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 96.5;Inhibitory neurons: 176.6;Oligodendrocyte precursor cells: 79.4;Theca cells: 98.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013180 Uncertain Approved "Golgi apparatus" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA013180: AB_1854383" "unprognostic (2.67e-2)" "unprognostic (3.46e-2)" "unprognostic (3.90e-1)" "unprognostic (1.51e-3)" "unprognostic (2.25e-1)" "unprognostic (5.26e-3)" "unprognostic (1.10e-2)" "unprognostic (5.73e-2)" "unprognostic (1.92e-2)" "unprognostic (2.32e-1)" "unprognostic (1.26e-1)" "unprognostic (3.98e-1)" "prognostic unfavorable (5.53e-6)" "unprognostic (3.48e-2)" "unprognostic (1.66e-1)" "unprognostic (6.79e-2)" "unprognostic (1.32e-1)" 2.7 7.2 6.1 6.4 19.8 2.4 2.8 3.6 9.3 1.6 1.0 8.5 1.6 2.2 0.6 6.1 0.8 4.8 2.6 4.1 8.3 2.7 0.7 5.9 6.3 6.9 0.8 1.6 2.5 10.7 1.2 3.4 6.4 1.1 2.4 7.5 2.7 1.2 4.4 1.8 2.8 1.6 1.7 22.7 2.2 8.0 3.5 5.4 8.8 2.2 6.2 4.9 2.9 4.2 86.8 94.4 133.9 0.3 19.3 111.6 22.2 84.0 13.2 72.9 39.3 19.9 54.0 21.3 50.4 18.0 70.2 37.9 86.4 83.6 89.0 0.3 55.7 17.2 32.8 21.3 23.9 55.8 43.7 67.9 54.7 29.5 41.2 70.5 49.2 50.5 25.9 25.7 47.4 23.5 31.9 30.4 64.7 25.8 68.8 0.1 26.2 43.0 51.4 18.3 87.8 63.5 110.9 8.6 12.5 21.8 1.7 40.3 24.1 0.1 0.3 0.1 0.5 27.5 24.7 47.6 58.9 38.9 59.6 0.3 0.9 0.0 0.0 0.5 0.3 0.2 0.3 0.0 0.6 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.5 0.1 6.1 19.8 3.6 9.3 4.1 8.3 6.9 0.8 6.4 1.7 3.5 4.2 4.9 0.0 4.5 4.6 6.5 7.8 0.6 10.4 13.1 2.2 5.2 8.9 1.3 0.0 3.6 0.0 0.0 1.4 2.1 15.9 0.0 0.4 3.1 2.1 4.0 10.6 10.8 0.4 96.5 3.1 0.5 4.9 1.5 0.9 2.5 18.0 2.9 0.4 6.6 0.0 176.6 2.6 6.1 11.4 14.6 5.7 0.6 16.6 3.6 8.4 7.3 39.9 1.0 79.4 3.1 1.3 1.5 0.0 13.7 4.9 2.9 0.1 2.4 1.6 6.6 5.3 3.6 17.9 22.2 18.8 3.3 0.8 5.2 98.7 2.8 1.4 NEXN "NELIN, nexilin" ENSG00000162614 "Nexilin F-actin binding protein" Q0ZGT2 1 77888513-77943895 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 404.8;skeletal muscle: 676.9;tongue: 548.9" "Cell type enriched" "Detected in many" 6 "Cardiomyocytes: 2329.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 152.2;LHCN-M2: 135.1;RH-30: 108.5" "Region enhanced" "Detected in all" "basal ganglia: 40.4" "Group enriched" "Detected in all" 4 "basal ganglia: 9.0;midbrain: 13.4;pons: 10.0;thalamus: 25.2" "HPA011185, HPA011904" Approved Supported "Plasma membrane,Actin filaments" NA NA 2900000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Actin filaments" "HPA011185: AB_1854409, HPA011904: " "unprognostic (9.73e-2)" "unprognostic (6.72e-2)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.72e-2)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (1.62e-2)" "unprognostic (1.09e-1)" "unprognostic (3.03e-2)" "unprognostic (2.22e-1)" "unprognostic (1.46e-1)" "unprognostic (3.25e-1)" "unprognostic (5.41e-2)" "unprognostic (5.60e-2)" "unprognostic (2.48e-1)" "unprognostic (9.65e-3)" "unprognostic (3.68e-2)" 42.8 22.3 2.3 24.5 3.1 0.6 16.2 1.7 1.6 21.9 2.5 89.2 10.2 79.0 10.7 49.4 47.5 28.7 404.8 1.3 1.8 8.0 5.6 25.2 5.6 1.4 3.3 15.2 10.0 1.5 1.4 10.6 1.5 62.5 15.7 0.6 11.5 69.8 676.9 6.8 26.7 70.6 1.2 8.6 44.1 5.7 4.7 2.1 10.3 548.9 1.8 49.7 19.5 1.7 26.0 1.5 4.5 0.2 79.5 75.3 12.3 152.2 65.5 29.8 20.2 4.6 0.2 0.0 8.6 54.7 34.4 3.4 3.3 14.3 53.3 0.7 3.4 6.2 7.5 1.5 59.3 1.3 0.2 56.6 3.3 40.7 23.8 65.2 22.8 6.0 0.3 0.0 135.1 0.0 29.9 1.8 23.8 0.0 18.6 24.3 108.5 0.2 35.5 1.2 0.1 1.1 13.3 0.0 1.0 29.9 0.0 3.5 23.4 71.7 53.6 31.2 76.1 0.2 0.2 0.1 4.0 2.8 0.2 0.0 1.7 0.0 0.2 1.0 0.0 0.7 0.1 0.2 0.9 0.5 0.3 0.1 1.4 0.3 0.8 0.6 0.0 3.6 2.3 3.1 1.7 1.6 1.3 1.8 1.4 3.3 1.5 1.2 4.7 1.7 8.3 105.8 4.9 11.4 2.1 1.8 0.9 4.6 1.2 2.7 1.4 33.1 2329.6 0.0 5.4 0.0 4.2 0.8 4.1 0.4 1.9 15.3 24.0 2.6 24.2 17.4 0.0 1.7 26.6 32.4 4.0 93.2 1.1 3.2 1.3 29.7 38.6 1.5 1.2 1.7 27.6 0.5 0.0 4.4 2.2 9.0 73.3 44.9 0.0 16.9 5.8 0.7 0.0 24.6 27.3 21.8 0.1 346.1 0.3 1.3 5.3 0.7 0.4 3.8 216.9 70.4 177.2 0.7 3.6 0.8 0.9 0.3 2.3 13.0 2.1 0.4 NFAM1 CNAIP ENSG00000235568 "NFAT activating protein with ITAM motif 1" Q8NET5 22 42380407-42432403 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 30.9;lymphoid tissue: 19.9" "Cell type enhanced" "Detected in some" "granulocytes: 11.4;Hofbauer cells: 17.0;Kupffer cells: 53.9;Macrophages: 27.2;monocytes: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 90.4" "Group enriched" "Detected in many" 4 "granulocytes: 90.4;monocytes: 48.2" "Cell line enriched" "Detected in some" 4 "THP-1: 37.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA031812 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA031812: AB_10603121" "unprognostic (9.77e-3)" "unprognostic (2.77e-3)" "unprognostic (8.21e-2)" "prognostic favorable (6.16e-4)" "unprognostic (4.83e-2)" "unprognostic (8.76e-3)" "unprognostic (2.34e-1)" "unprognostic (1.08e-1)" "unprognostic (9.12e-3)" "unprognostic (9.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.00e-1)" "unprognostic (8.12e-3)" "unprognostic (1.75e-1)" "unprognostic (4.42e-2)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" 6.3 1.9 1.5 12.4 1.9 30.9 1.1 1.5 2.2 1.8 2.0 1.5 1.3 0.6 0.6 1.3 2.0 2.3 1.3 1.8 2.4 1.2 2.3 7.5 5.5 3.1 2.2 0.3 0.8 0.3 0.6 2.9 2.9 0.9 1.2 0.1 0.8 1.4 0.4 1.4 2.3 2.9 2.3 19.9 1.1 0.7 2.9 2.1 0.7 1.5 2.1 3.1 0.7 3.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.6 0.0 0.0 0.1 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 8.8 0.2 0.0 0.0 0.2 0.0 0.0 0.4 0.1 5.8 0.0 0.0 0.1 0.0 0.4 0.0 37.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.3 48.2 2.8 0.1 32.5 0.2 0.0 0.1 0.0 16.5 0.1 0.0 0.0 90.4 0.0 31.1 0.3 0.0 25.4 1.5 1.9 1.5 2.2 1.8 2.4 3.1 2.2 2.9 2.3 2.9 3.0 0.4 0.0 3.7 0.0 0.5 0.9 0.7 0.9 0.6 0.2 0.4 0.0 0.6 1.5 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 2.8 0.4 0.2 0.5 1.2 0.0 0.7 0.2 0.1 0.5 0.0 0.3 11.4 0.0 0.7 0.6 17.0 0.0 0.6 0.0 0.0 53.9 8.2 5.6 0.3 27.2 0.0 8.4 44.6 0.0 0.0 2.0 0.5 0.0 0.0 0.4 0.1 0.1 0.0 0.1 0.1 0.5 0.0 0.5 0.5 0.8 0.7 0.0 1.0 0.3 1.3 0.4 0.0 0.5 NFASC "FLJ46866, KIAA0756, NF, NRCAML" ENSG00000163531 Neurofascin O94856 1 204828651-205022822 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 151.0;Excitatory neurons: 148.4;Horizontal cells: 220.4;Inhibitory neurons: 139.0;Oligodendrocyte precursor cells: 87.9;Oligodendrocytes: 226.6;Rod photoreceptor cells: 195.5" "Cancer enriched" "Detected in many" 5 "glioma: 8.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 27.6;fHDF/TERT166: 50.3;hTERT-RPE1: 24.0;SCLC-21H: 22.8;U-138 MG: 62.7;U-87 MG: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008832 Enhanced NA NA 2200000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "HPA008832: AB_1854411" "unprognostic (1.71e-1)" "unprognostic (1.07e-1)" "unprognostic (2.62e-1)" "unprognostic (3.39e-2)" "unprognostic (6.65e-2)" "unprognostic (1.18e-2)" "unprognostic (3.71e-3)" "unprognostic (3.37e-1)" "unprognostic (6.34e-3)" "unprognostic (2.79e-1)" "prognostic favorable (3.21e-5)" "unprognostic (3.76e-1)" "prognostic unfavorable (2.93e-5)" "unprognostic (1.56e-3)" "unprognostic (1.91e-1)" "unprognostic (6.90e-2)" "unprognostic (5.26e-3)" 5.2 7.5 7.8 3.7 31.5 0.1 3.2 8.4 15.2 5.0 0.0 8.6 4.5 8.3 9.0 10.0 12.1 5.9 15.3 10.7 5.6 9.8 1.9 5.0 2.3 13.1 14.1 10.1 5.9 1.0 5.6 10.6 7.8 7.5 5.9 22.6 2.1 16.3 3.0 4.3 5.0 14.2 3.9 6.5 4.4 1.5 35.6 0.6 2.9 3.8 2.9 9.4 7.7 50.1 0.0 0.1 3.1 0.1 0.4 1.0 0.1 27.6 0.0 19.9 5.9 0.2 0.1 0.0 0.1 50.3 18.5 13.4 0.6 0.8 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.1 12.7 0.7 24.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 7.0 0.9 0.3 0.0 2.3 0.0 0.0 0.0 22.8 1.3 0.0 1.5 0.0 2.0 0.3 0.0 0.0 62.7 13.5 0.1 0.0 0.0 0.0 0.0 31.3 0.0 16.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 31.5 8.4 15.2 10.7 5.6 13.1 14.1 7.8 3.9 35.6 50.1 2.5 0.0 0.6 64.3 0.0 2.2 1.5 1.9 0.6 151.0 1.7 10.5 23.9 1.5 1.5 0.0 12.5 0.5 0.0 0.3 0.0 0.2 7.3 0.5 0.4 7.6 37.8 0.0 148.4 0.0 0.5 14.2 1.1 0.1 0.0 0.1 3.3 1.7 0.4 220.4 139.0 6.0 0.0 0.6 1.9 17.9 6.5 0.4 1.8 15.0 0.0 14.2 0.0 87.9 226.6 0.5 0.5 5.7 0.0 1.1 0.0 1.5 5.9 195.5 52.6 2.3 49.9 1.7 3.9 5.5 4.7 0.7 0.3 0.7 1.0 0.8 NFATC2IP "ESC2, FLJ14639, NIP45, RAD60" ENSG00000176953 "Nuclear factor of activated T cells 2 interacting protein" Q8NCF5 16 28950807-28967097 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053587 Approved Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA053587: AB_2682202" "unprognostic (6.01e-2)" "unprognostic (1.41e-2)" "unprognostic (8.48e-2)" "unprognostic (1.33e-1)" "unprognostic (4.90e-1)" "unprognostic (7.09e-2)" "unprognostic (8.82e-3)" "unprognostic (1.15e-2)" "unprognostic (8.95e-2)" "unprognostic (5.80e-2)" "unprognostic (5.32e-2)" "prognostic unfavorable (5.23e-4)" "prognostic unfavorable (1.03e-5)" "unprognostic (8.00e-2)" "unprognostic (3.85e-2)" "unprognostic (3.25e-1)" "unprognostic (5.94e-2)" 20.9 16.6 10.4 27.6 10.5 48.6 21.7 15.6 11.0 25.2 9.9 30.6 21.1 23.3 14.4 29.0 24.5 14.3 20.9 11.0 9.1 26.0 27.9 25.8 36.6 11.1 10.6 24.1 22.7 20.0 15.0 15.5 11.1 23.9 32.2 26.6 24.3 15.5 25.7 32.5 36.9 22.8 9.8 45.4 25.9 30.3 12.1 34.3 22.0 15.8 38.5 26.0 23.5 11.7 38.6 27.2 36.5 36.7 21.7 22.8 46.0 36.7 27.6 42.1 53.7 32.0 47.0 41.1 27.0 26.4 25.6 44.8 44.3 40.3 56.9 35.0 32.4 37.5 81.2 39.8 13.9 34.1 55.0 16.1 32.1 45.9 27.6 20.8 34.3 40.9 34.4 49.5 37.8 47.9 44.9 60.2 35.9 30.9 32.0 77.0 32.4 37.5 30.2 34.2 28.0 20.0 24.7 37.7 14.4 29.6 39.1 25.2 38.1 46.3 26.1 36.5 28.1 36.5 51.5 49.7 25.6 55.5 27.8 5.0 1.5 1.8 1.9 2.0 1.8 1.5 1.4 2.3 0.9 1.5 2.3 2.0 1.1 2.8 1.2 3.2 2.4 0.7 10.4 10.5 15.6 11.0 11.0 9.1 11.1 10.6 11.1 9.8 12.1 11.7 40.9 35.3 52.2 15.7 43.1 31.7 23.0 19.1 33.0 63.1 29.4 25.7 17.4 21.5 29.8 29.5 100.1 30.1 69.8 51.3 19.6 21.9 6.3 28.3 43.6 35.1 40.9 77.2 21.3 22.9 30.5 23.3 50.0 37.6 36.7 69.5 38.9 26.0 23.2 43.7 27.0 63.1 18.3 38.8 32.2 7.6 29.5 37.8 23.2 26.2 56.7 15.3 57.7 19.6 18.2 44.6 31.6 20.3 55.4 40.4 40.7 17.8 21.7 84.5 39.5 26.7 26.6 95.0 92.2 35.7 30.3 26.1 51.4 38.3 53.0 42.1 NHSL2 ENSG00000204131 "NHS like 2" Q5HYW2 X 71910818-72161750 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 101.2;monocytes: 57.7;Prostatic glandular cells: 90.5;Urothelial cells: 80.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 14.3;neutrophil: 15.6" "Group enriched" "Detected in many" 4 "dendritic cells: 4.1;granulocytes: 15.6;monocytes: 7.1" "Cell line enhanced" "Detected in some" "AF22: 25.2;EFO-21: 29.5;HUVEC TERT2: 27.8;TIME: 16.3;U-937: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049771, HPA075115" Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA049771: AB_2680872, HPA075115: " "unprognostic (9.71e-3)" "unprognostic (1.96e-1)" "unprognostic (1.92e-1)" "unprognostic (4.56e-2)" "unprognostic (1.40e-1)" "unprognostic (5.50e-2)" "unprognostic (2.88e-2)" "unprognostic (5.72e-4)" "unprognostic (5.46e-2)" "unprognostic (3.36e-2)" "unprognostic (1.50e-2)" "unprognostic (1.91e-1)" "unprognostic (1.61e-2)" "unprognostic (4.27e-3)" "unprognostic (9.99e-2)" "unprognostic (7.76e-2)" "unprognostic (4.37e-4)" 4.7 1.3 8.1 3.0 9.6 2.2 3.2 11.8 6.6 3.2 12.3 4.9 0.8 3.2 1.4 3.1 2.3 4.3 2.2 6.6 5.9 1.1 0.9 3.4 0.8 1.5 9.1 1.6 0.6 1.6 2.6 2.2 4.6 3.5 1.9 0.3 1.5 4.8 0.8 1.4 1.7 6.9 0.8 2.8 1.9 2.4 6.9 1.0 2.7 2.4 0.9 3.7 2.3 0.0 0.4 0.6 25.2 0.1 0.3 1.0 0.2 0.9 4.7 0.1 0.4 0.1 0.0 0.2 29.5 2.6 0.1 0.0 1.6 0.0 0.6 0.1 0.6 0.1 0.1 0.0 0.1 0.1 1.4 0.5 0.0 0.9 0.0 0.1 27.8 0.1 0.0 4.1 0.2 0.2 0.1 2.1 4.8 0.0 0.0 0.1 1.4 0.0 0.1 2.9 0.6 5.7 0.0 0.0 0.0 7.1 0.1 1.7 16.3 0.0 1.6 2.0 0.0 0.1 0.0 0.1 1.1 20.5 0.0 5.0 7.1 14.3 2.0 4.7 1.9 0.0 1.0 1.7 4.1 0.0 0.1 0.2 15.6 1.0 3.7 0.0 0.1 2.3 8.1 9.6 11.8 6.6 6.6 5.9 1.5 9.1 4.6 0.8 6.9 0.0 29.2 0.0 1.9 1.0 7.3 0.5 101.2 0.0 0.6 0.9 5.0 3.7 19.6 21.5 0.0 1.8 0.0 17.9 10.1 2.0 0.0 0.2 4.7 3.3 2.8 32.9 1.2 17.3 7.8 0.7 24.3 15.2 0.5 9.0 7.6 0.9 51.0 19.0 19.1 0.0 5.8 3.7 0.0 49.0 0.5 7.4 31.7 19.7 1.8 19.7 57.7 1.5 32.0 5.5 1.1 0.6 3.1 21.4 2.8 90.5 7.8 2.9 0.0 0.5 26.3 39.7 12.6 2.7 3.7 0.3 0.3 24.9 17.0 2.9 3.8 80.7 NIBAN2 "bA356B19.6, C9orf88, DKFZP434H0820, FAM129B, FLJ13518, FLJ22151, FLJ22298, MINERVA" ENSG00000136830 "Niban apoptosis regulator 2" Q96TA1 9 127505339-127578989 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 606.7" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 73.6;Extravillous trophoblasts: 40.5;Hofbauer cells: 23.0;Syncytiotrophoblasts: 120.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021284, HPA021417, HPA023261, HPA024312" Enhanced Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA 1500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" Nucleoplasm "HPA021284: AB_1848373, HPA021417: AB_1848374, HPA023261: AB_1848375, HPA024312: AB_1848376" "unprognostic (3.05e-3)" "unprognostic (9.47e-2)" "unprognostic (1.14e-3)" "unprognostic (4.07e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-1)" "unprognostic (3.14e-2)" "unprognostic (2.57e-3)" "unprognostic (1.40e-1)" "unprognostic (1.68e-2)" "unprognostic (1.17e-3)" "unprognostic (6.45e-2)" "unprognostic (3.75e-2)" "unprognostic (1.24e-2)" "unprognostic (1.31e-1)" "unprognostic (8.40e-2)" "unprognostic (8.20e-3)" 48.7 107.5 26.7 36.6 24.7 27.3 42.0 25.2 24.5 96.0 45.3 74.6 50.8 38.9 12.6 606.7 39.4 39.6 39.4 22.7 35.0 72.3 16.7 121.9 6.6 48.9 34.3 31.6 142.6 26.2 34.0 84.8 36.3 66.5 30.3 2.7 142.1 32.2 13.6 111.3 53.9 22.0 39.7 32.2 83.3 11.0 34.7 5.6 110.6 11.3 53.6 68.4 189.6 31.9 134.0 149.8 29.9 39.3 87.9 170.1 138.2 259.1 238.5 140.1 86.4 48.2 143.7 0.4 100.4 295.5 172.9 217.5 25.9 192.2 45.9 25.2 27.5 22.8 218.9 50.4 173.1 1.0 62.0 187.3 118.3 231.4 80.8 256.8 213.6 8.4 43.5 1.2 269.8 157.3 1.6 37.6 30.9 228.0 194.4 16.0 99.9 70.1 120.5 105.6 47.4 22.1 212.3 149.0 93.4 42.1 98.2 7.5 279.9 143.1 62.4 182.2 218.0 2.5 5.1 0.6 403.3 21.6 271.1 0.2 1.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 26.7 24.7 25.2 24.5 22.7 35.0 48.9 34.3 36.3 39.7 34.7 31.9 12.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 73.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 40.5 4.2 0.0 0.0 0.0 0.0 0.0 0.0 23.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 120.9 0.1 0.0 0.0 0.0 NICN1 MGC12936 ENSG00000145029 "Nicolin 1" Q9BSH3 3 49422333-49429326 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 24.3;Late spermatids: 52.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058014 Supported Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA058014: AB_2683579" "unprognostic (4.10e-2)" "unprognostic (1.08e-2)" "unprognostic (7.31e-2)" "unprognostic (1.33e-3)" "unprognostic (1.14e-1)" "unprognostic (1.31e-2)" "unprognostic (1.31e-2)" "unprognostic (4.50e-3)" "unprognostic (1.04e-2)" "unprognostic (2.88e-2)" "prognostic favorable (1.11e-4)" "unprognostic (2.46e-1)" "prognostic favorable (8.81e-7)" "unprognostic (3.11e-2)" "unprognostic (2.37e-1)" "unprognostic (1.03e-2)" "unprognostic (2.96e-2)" 7.8 11.2 20.1 4.6 22.5 2.6 7.8 16.9 24.0 9.7 15.6 11.7 4.3 10.5 8.1 5.8 10.2 5.5 11.5 21.8 18.0 16.9 10.5 8.3 6.9 18.8 18.2 11.1 7.6 9.9 11.6 4.5 20.4 11.5 4.0 9.0 9.1 6.8 12.5 6.7 7.9 6.6 17.8 9.9 9.7 11.8 20.0 10.6 13.6 9.9 6.5 9.1 8.1 21.6 3.7 10.9 11.8 9.6 5.1 6.1 3.8 4.6 4.0 3.8 5.2 2.6 10.9 10.8 4.0 9.1 8.0 3.1 6.4 5.6 4.3 18.2 4.2 10.6 12.2 13.0 9.5 4.2 6.6 13.0 7.2 8.7 3.1 19.8 5.8 22.6 6.5 0.2 4.2 3.5 6.7 6.3 3.5 4.1 3.4 5.9 3.8 13.5 7.0 2.1 1.9 4.6 3.8 3.1 8.0 22.1 5.9 2.1 12.2 3.1 3.2 3.0 1.7 13.7 4.1 3.7 9.3 11.6 5.1 5.3 3.7 3.1 4.1 3.1 2.7 5.0 2.4 5.0 3.3 2.1 3.1 3.7 0.8 4.1 5.2 4.2 6.2 3.8 20.1 22.5 16.9 24.0 21.8 18.0 18.8 18.2 20.4 17.8 20.0 21.6 0.0 0.0 1.1 4.9 3.7 4.1 5.6 7.6 1.8 6.8 0.0 0.0 14.3 5.7 3.3 0.0 10.4 6.2 4.0 2.3 0.0 0.0 24.3 0.0 0.0 2.9 12.1 6.5 4.4 0.0 2.2 3.3 8.6 0.0 1.3 0.0 3.9 5.5 5.8 3.3 4.9 4.2 0.0 5.2 3.0 52.7 9.6 1.7 3.6 1.9 1.0 6.2 9.2 3.0 2.9 0.0 1.6 6.0 3.5 2.2 5.4 0.0 3.0 6.8 6.6 4.7 2.8 11.0 2.3 3.3 3.3 3.3 3.8 0.1 3.4 4.6 NIPSNAP1 ENSG00000184117 "Nipsnap homolog 1" Q9BPW8 22 29554808-29581327 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 291.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 116.7;Proximal tubular cells: 134.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA059227 Uncertain NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA059227: AB_2683951" "unprognostic (7.45e-2)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (2.15e-2)" "unprognostic (7.25e-2)" "unprognostic (6.91e-2)" "unprognostic (3.20e-1)" "unprognostic (1.22e-1)" "unprognostic (1.35e-1)" "unprognostic (1.43e-2)" "unprognostic (1.23e-2)" "unprognostic (1.78e-1)" "prognostic favorable (8.82e-6)" "unprognostic (2.81e-2)" "unprognostic (8.69e-2)" "unprognostic (9.03e-2)" "unprognostic (1.72e-1)" 10.7 43.9 35.4 17.5 37.8 15.5 31.5 31.8 38.5 21.5 33.4 37.4 67.0 19.4 24.9 25.8 26.8 19.8 21.8 37.6 41.7 117.8 291.8 17.8 23.3 37.1 36.5 32.3 24.4 68.0 36.5 17.3 39.3 23.9 38.5 46.2 26.0 27.2 4.4 20.6 49.2 17.8 30.7 19.1 29.3 11.9 36.7 36.7 32.9 5.4 28.3 20.1 18.3 31.7 69.1 81.1 165.3 206.9 29.2 59.4 30.7 39.5 70.7 53.2 68.7 55.5 90.6 48.8 76.8 56.9 56.0 68.2 87.7 100.7 65.1 98.8 90.5 16.8 37.0 173.5 44.1 36.5 23.0 59.5 50.8 44.1 55.0 129.0 73.4 105.3 31.8 78.9 49.2 156.4 59.3 50.1 140.0 106.2 67.5 115.9 51.7 142.6 128.3 59.1 203.9 179.5 46.1 83.2 92.1 79.5 137.1 57.7 34.7 23.2 79.6 28.6 31.9 106.4 56.5 45.6 62.1 57.3 39.4 10.8 9.4 15.9 34.2 17.4 41.2 29.0 34.4 36.2 21.6 27.3 32.6 39.5 13.8 39.5 10.7 11.0 44.9 22.1 35.4 37.8 31.8 38.5 37.6 41.7 37.1 36.5 39.3 30.7 36.7 31.7 7.4 25.6 15.7 6.8 16.3 4.8 12.6 15.8 18.8 22.6 25.5 18.5 22.9 28.6 18.6 42.3 10.4 44.4 9.2 14.4 68.4 45.8 2.1 6.2 13.7 10.1 41.9 24.6 16.9 18.5 14.6 14.2 25.5 12.0 26.0 33.5 11.7 116.7 14.4 10.1 19.9 31.5 26.4 8.7 4.3 6.1 11.1 8.1 5.4 3.7 21.3 38.7 28.8 6.6 10.3 17.8 20.2 14.3 7.3 6.8 35.2 134.7 9.8 24.4 13.1 7.2 12.3 1.4 8.3 20.5 8.1 14.8 20.5 48.1 47.4 8.8 NKG7 "GIG1, GMP-17" ENSG00000105374 "Natural killer cell granule protein 7" Q16617 19 51371606-51372701 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 602.6;lymphoid tissue: 154.6" "Group enriched" "Detected in many" 4 "dendritic cells: 3163.4;NK-cells: 7721.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 6827.0;MAIT T-cell: 2871.2;memory CD8 T-cell: 4295.0;naive CD8 T-cell: 3114.2;NK-cell: 4796.8" "Group enriched" "Detected in all" 44 "NK-cells: 4796.8;T-cells: 6827.0" "Group enriched" "Detected in some" 5 "NB-4: 180.8;THP-1: 54.5;U-937: 46.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071454 Approved Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA071454: AB_2686399" "unprognostic (1.56e-2)" "unprognostic (1.05e-2)" "unprognostic (6.54e-2)" "prognostic favorable (7.42e-6)" "unprognostic (1.27e-2)" "unprognostic (3.25e-3)" "unprognostic (2.96e-3)" "unprognostic (2.14e-1)" "unprognostic (3.22e-3)" "unprognostic (3.89e-3)" "unprognostic (3.39e-1)" "unprognostic (9.93e-2)" "prognostic unfavorable (3.32e-6)" "unprognostic (7.62e-3)" "unprognostic (2.61e-1)" "unprognostic (1.30e-2)" "unprognostic (6.44e-3)" 12.5 7.9 3.7 23.2 3.6 602.6 7.7 3.6 6.3 5.9 4.2 9.5 11.0 12.5 6.1 7.2 7.9 21.4 6.7 3.5 3.6 6.5 23.5 49.2 136.4 4.9 3.9 4.2 2.2 2.2 3.2 7.9 4.2 4.9 7.3 0.4 9.6 4.5 6.5 2.7 14.6 7.7 4.1 154.6 10.6 3.3 4.3 9.4 6.6 3.3 21.9 16.7 4.4 4.2 0.1 0.3 0.2 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.9 7.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 7.6 0.6 2.0 0.8 0.2 0.0 20.1 3.6 0.0 0.0 0.3 0.0 0.2 0.0 2.5 0.5 0.8 0.0 0.0 2.4 180.8 0.0 0.2 0.3 4.4 9.4 0.4 0.0 0.0 0.1 0.2 0.4 0.1 0.1 0.3 0.0 54.5 0.4 0.1 0.2 0.6 0.1 2.6 0.9 0.9 0.1 46.6 0.0 76.9 34.1 15.2 6827.0 131.7 2871.2 37.9 811.1 4295.0 87.1 15.4 261.0 3114.2 111.7 4796.8 104.8 67.1 17.5 4929.2 3.7 3.6 3.6 6.3 3.5 3.6 4.9 3.9 4.2 4.1 4.3 4.2 17.2 3.2 8.0 0.0 24.5 5.0 0.1 0.0 0.0 0.0 5.7 3.7 0.7 28.6 1.3 5.5 0.0 1.0 3163.4 1.9 3.9 1.0 0.2 2.7 3.6 7.1 0.0 186.5 0.0 0.0 0.8 5.2 17.3 4.2 24.1 0.2 55.3 9.9 15.0 0.0 0.0 0.5 0.0 132.9 10.2 0.3 0.0 55.5 17.8 1.0 49.4 0.0 7721.0 0.0 0.2 0.0 1.2 0.0 120.4 0.0 0.6 9.2 0.7 0.0 0.0 6.4 4.7 0.0 0.5 1.1 6.5 1.1 1321.5 0.0 1.1 0.1 NLGN2 KIAA1366 ENSG00000169992 "Neuroligin 2" Q8NFZ4 17 7404874-7419860 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 32.7;Horizontal cells: 57.2;Oligodendrocyte precursor cells: 45.8;Sertoli cells: 32.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 42.2" "Low region specificity" "Detected in all" "HPA055321, HPA069278" Enhanced Approved Mitochondria NA NA 14000 "Cluster 72: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Mitochondria "HPA055321: AB_2682783, HPA069278: AB_2686105" "unprognostic (1.31e-1)" "unprognostic (1.87e-2)" "unprognostic (4.35e-3)" "unprognostic (2.58e-1)" "unprognostic (1.12e-1)" "unprognostic (9.79e-3)" "unprognostic (2.92e-1)" "unprognostic (1.56e-1)" "unprognostic (6.50e-2)" "unprognostic (2.24e-2)" "unprognostic (5.58e-3)" "unprognostic (1.23e-2)" "prognostic unfavorable (3.44e-4)" "unprognostic (1.69e-1)" "unprognostic (2.85e-1)" "unprognostic (5.50e-3)" "unprognostic (1.81e-2)" 25.0 18.1 25.6 4.8 26.0 0.4 21.2 13.5 25.3 61.9 0.0 36.4 1.5 57.9 7.5 10.2 46.1 7.7 18.2 23.7 18.6 16.6 9.3 16.7 2.7 18.1 15.2 66.6 9.4 7.6 23.7 3.8 13.9 29.7 2.2 15.5 13.6 9.0 11.7 14.8 16.6 12.3 12.1 16.9 16.3 6.7 20.9 0.8 14.2 2.4 1.8 31.2 32.4 19.0 7.1 9.8 42.2 24.4 12.6 18.0 1.0 11.6 18.2 19.4 17.9 2.2 2.4 0.1 5.5 16.4 11.4 3.9 7.9 4.9 10.0 10.8 7.9 3.1 9.6 1.6 6.3 3.1 10.4 14.1 3.8 15.9 2.4 29.1 6.5 3.9 2.9 5.6 7.9 6.6 1.4 3.1 7.2 0.4 4.7 12.9 5.0 1.4 5.6 1.5 0.6 17.0 5.3 2.5 3.0 8.3 6.9 0.4 9.0 16.6 20.6 10.5 5.7 6.4 2.2 1.2 17.3 2.8 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.6 26.0 13.5 25.3 23.7 18.6 18.1 15.2 13.9 12.1 20.9 19.0 5.4 0.0 2.6 25.8 0.5 4.7 3.1 3.3 7.4 32.7 5.6 5.2 11.0 5.7 1.0 0.0 8.4 0.4 3.4 0.1 0.0 2.7 2.0 1.5 25.3 6.8 0.0 0.0 23.5 0.4 6.3 11.5 0.5 2.3 0.0 5.8 6.1 3.2 1.0 57.2 24.8 0.3 0.0 0.8 1.8 2.9 17.1 0.7 1.8 5.6 0.6 22.3 0.0 45.8 13.6 1.6 0.0 22.2 0.3 3.0 0.1 1.3 0.8 16.8 32.9 10.8 10.7 0.5 1.1 1.2 3.8 0.8 1.7 4.3 0.3 1.2 NLGN4X "HLNX, KIAA1260, NLGN, NLGN4" ENSG00000146938 "Neuroligin 4 X-linked" Q8N0W4 X 5840637-6228867 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Asperger syndrome, Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.5;lymphoid tissue: 14.3" "Cell type enhanced" "Detected in many" "Astrocytes: 113.9;Excitatory neurons: 162.2;Inhibitory neurons: 236.8;Oligodendrocyte precursor cells: 702.7" "Group enriched" "Detected in many" 4 "endometrial cancer: 2.7;glioma: 8.5;testis cancer: 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 55.6;NTERA-2: 44.1;SuSa: 42.7" HPA001651 Approved NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "HPA001651: AB_1079470" "unprognostic (2.21e-1)" "unprognostic (4.01e-2)" "unprognostic (1.11e-1)" "unprognostic (8.57e-2)" "unprognostic (1.28e-1)" "unprognostic (1.52e-1)" "unprognostic (1.36e-1)" "unprognostic (1.04e-1)" "unprognostic (1.67e-1)" "unprognostic (9.49e-2)" "unprognostic (1.48e-2)" "unprognostic (9.32e-2)" "unprognostic (5.10e-3)" "unprognostic (7.16e-4)" "unprognostic (6.70e-2)" "unprognostic (2.98e-2)" "unprognostic (1.10e-2)" 3.4 1.3 8.8 1.8 10.1 0.0 2.2 9.8 12.7 5.1 0.0 3.4 1.3 2.3 0.4 0.7 2.0 2.5 4.5 14.8 28.5 0.3 1.3 1.1 0.8 6.5 5.6 11.6 0.4 5.2 1.7 3.6 4.4 1.1 1.9 9.2 0.8 1.9 0.3 0.6 2.6 3.7 1.6 2.2 1.1 2.6 8.9 14.3 0.7 0.2 0.5 2.1 1.4 4.2 0.0 0.0 55.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 7.4 0.0 44.1 0.0 0.1 0.0 0.0 0.1 4.1 11.5 2.7 3.5 0.0 0.1 0.0 42.7 5.7 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 10.1 9.8 12.7 14.8 28.5 6.5 5.6 4.4 1.6 8.9 4.2 12.1 0.0 0.5 113.9 0.3 0.3 0.1 0.2 0.0 15.0 5.2 3.4 2.8 0.0 0.1 0.0 25.0 3.7 0.1 0.0 0.0 0.0 0.1 19.7 69.5 2.5 0.0 0.0 162.2 0.0 2.4 9.6 0.0 33.2 0.0 2.2 1.8 0.0 0.6 0.0 236.8 0.0 0.0 0.3 0.5 0.7 18.0 0.3 14.2 4.7 0.0 12.5 0.0 702.7 68.3 0.0 0.0 29.7 0.1 0.0 0.0 0.1 0.7 3.3 13.1 18.4 5.0 2.0 5.5 0.2 0.6 3.6 0.5 8.8 0.0 0.3 NLN "AGTBP, KIAA1226" ENSG00000123213 Neurolysin Q9BYT8 5 65722205-65871725 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 52.8;Excitatory neurons: 58.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.6;intermediate monocyte: 3.4;myeloid DC: 2.2;non-classical monocyte: 2.3" "Group enriched" "Detected in many" 5 "dendritic cells: 2.2;monocytes: 3.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031862 Approved Approved Mitochondria Yes No 64000 "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA031862: AB_10600827" "unprognostic (5.91e-3)" "unprognostic (4.52e-2)" "unprognostic (1.34e-3)" "unprognostic (4.37e-2)" "unprognostic (3.85e-1)" "unprognostic (1.45e-2)" "unprognostic (7.29e-3)" "unprognostic (3.24e-2)" "unprognostic (3.19e-1)" "unprognostic (3.58e-1)" "prognostic unfavorable (7.51e-4)" "unprognostic (1.27e-1)" "prognostic favorable (5.58e-7)" "unprognostic (1.52e-2)" "unprognostic (1.98e-1)" "unprognostic (1.29e-1)" "unprognostic (6.18e-3)" 2.2 1.0 3.8 2.4 3.9 1.5 3.7 2.9 5.3 1.8 1.6 3.6 1.1 2.7 2.4 2.5 1.5 1.2 2.6 3.8 3.6 3.9 9.9 1.7 1.7 3.9 3.4 1.8 2.5 1.5 0.9 2.4 4.0 2.6 3.2 2.5 1.9 1.1 8.9 2.8 2.7 2.7 3.3 1.3 4.0 1.1 3.9 0.9 2.7 6.5 2.0 2.7 1.5 4.8 13.3 12.5 7.2 12.0 9.0 15.3 14.5 13.1 5.5 7.6 8.2 7.2 7.7 18.8 16.1 15.8 15.1 10.3 9.5 20.2 13.1 5.6 6.4 5.2 8.7 18.5 7.7 12.0 3.0 11.7 10.8 10.5 12.4 6.3 21.7 8.3 11.4 3.9 16.5 10.2 8.3 10.8 22.2 6.7 3.6 9.6 15.3 29.9 12.6 5.9 22.3 11.5 10.6 10.7 11.0 19.4 12.9 14.1 12.5 5.0 5.9 7.4 10.0 3.3 7.1 8.2 7.7 23.2 7.7 0.1 2.6 0.1 0.1 3.4 0.1 0.4 0.2 0.1 2.2 0.4 0.3 0.2 0.3 0.5 2.3 0.1 0.0 1.0 3.8 3.9 2.9 5.3 3.8 3.6 3.9 3.4 4.0 3.3 3.9 4.8 5.9 6.4 2.8 19.6 4.0 5.7 9.0 6.2 8.6 2.4 10.1 8.9 14.5 7.2 8.5 12.9 4.2 5.3 0.6 52.8 5.9 17.8 0.3 7.4 12.9 8.3 1.8 9.0 58.9 14.5 14.0 7.1 20.4 20.9 15.2 16.2 4.6 32.4 28.8 5.0 32.2 5.8 6.1 22.9 8.9 0.4 4.4 13.5 1.8 5.6 17.9 13.1 2.1 22.6 44.5 30.2 35.9 2.2 4.9 16.5 32.3 22.4 3.1 4.7 0.0 19.7 8.1 2.1 5.2 15.3 5.3 2.9 2.3 15.8 8.2 6.1 NLRC3 "CLR16.2, FLJ00348, NOD3" ENSG00000167984 "NLR family CARD domain containing 3" Q7RTR2 16 3539033-3577403 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 6.5;lymphoid tissue: 13.6" "Cell type enhanced" "Detected in many" "B-cells: 10.3;dendritic cells: 18.8;NK-cells: 37.0;T-cells: 23.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 8.8;HEL: 8.7;HL-60: 18.6;HMC-1: 9.0;JURKAT: 9.2;NB-4: 19.7;U-698: 28.9;U-937: 13.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA048062 Supported "Vesicles,Centriolar satellite,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Vesicles, Centriolar satellite" "HPA048062: AB_2680242" "unprognostic (4.93e-3)" "unprognostic (3.84e-4)" "unprognostic (7.61e-4)" "unprognostic (4.94e-7)" "unprognostic (9.56e-2)" "unprognostic (3.76e-5)" "unprognostic (1.86e-3)" "unprognostic (6.70e-3)" "unprognostic (2.66e-2)" "unprognostic (7.02e-2)" "unprognostic (3.40e-2)" "unprognostic (5.20e-2)" "unprognostic (1.40e-2)" "unprognostic (5.13e-2)" "unprognostic (7.15e-3)" "unprognostic (4.54e-2)" "unprognostic (2.08e-2)" 1.0 0.8 0.3 7.8 0.4 4.1 0.7 0.8 0.7 0.9 1.0 1.5 1.7 0.9 0.4 0.8 1.2 1.4 1.5 0.3 0.0 1.3 1.1 2.4 13.6 0.3 0.3 0.7 0.5 0.2 0.9 0.9 0.1 1.1 1.2 1.1 1.1 0.3 1.1 0.5 6.5 0.5 0.0 11.8 2.1 0.9 0.3 11.3 1.5 0.9 11.1 1.5 0.8 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 8.8 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.2 8.7 0.1 0.0 0.0 18.6 9.0 0.0 0.0 0.0 0.0 0.5 0.2 9.2 0.2 0.0 0.0 0.4 7.7 19.7 0.0 0.0 0.1 5.1 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.3 0.1 0.1 4.9 0.5 0.3 0.1 0.2 0.1 0.4 0.2 28.9 0.2 13.6 0.1 2.9 0.0 0.0 2.3 0.0 2.1 0.8 1.7 2.2 0.0 0.6 1.4 1.5 0.0 2.6 0.0 0.0 2.0 2.1 0.3 0.4 0.8 0.7 0.3 0.0 0.3 0.3 0.1 0.0 0.3 0.1 1.7 3.2 0.0 1.0 10.3 0.0 0.3 0.0 0.0 1.6 0.4 0.3 4.6 1.5 0.6 1.8 4.2 0.0 18.8 0.0 0.0 0.0 4.0 1.3 0.8 2.3 0.0 6.5 3.8 0.0 0.0 0.5 1.5 0.7 2.5 0.2 3.9 0.1 0.1 0.0 3.7 0.0 0.0 1.0 0.0 1.3 0.0 1.1 0.0 1.9 1.3 0.3 37.0 1.0 0.6 0.0 0.0 0.0 6.2 0.1 0.0 0.1 0.7 5.1 0.0 0.9 0.7 0.5 0.3 0.0 0.0 0.0 23.8 0.1 0.0 0.3 NLRP12 "CLR19.3, Monarch1, NALP12, PAN6, PYPAF7, RNO2" ENSG00000142405 "NLR family pyrin domain containing 12" P59046 19 53793741-53824394 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;lymphoid tissue: 4.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 7.4;granulocytes: 7.6;Kupffer cells: 11.2;Macrophages: 7.8;monocytes: 20.5" "Cancer enriched" "Detected in single" 5 "testis cancer: 2.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "basophil: 56.9;classical monocyte: 18.1;eosinophil: 23.2;neutrophil: 29.8" "Group enriched" "Detected in many" 5 "granulocytes: 56.9;monocytes: 18.1" "Group enriched" "Detected in some" 4 "HMC-1: 4.6;THP-1: 4.1;U-87 MG: 4.3;U-937: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA042981 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA042981: AB_10795712" "unprognostic (6.92e-2)" "unprognostic (3.11e-1)" "unprognostic (6.66e-3)" "unprognostic (9.82e-2)" "unprognostic (1.81e-4)" "unprognostic (3.90e-2)" "unprognostic (5.79e-2)" "unprognostic (6.26e-2)" "unprognostic (1.29e-1)" "unprognostic (1.60e-5)" "unprognostic (1.63e-1)" "unprognostic (1.68e-1)" "unprognostic (3.35e-2)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (1.46e-2)" "unprognostic (4.48e-1)" 0.9 0.0 0.1 2.2 0.1 6.0 0.1 0.0 0.2 0.1 0.1 0.1 0.2 0.0 0.0 0.1 0.3 0.3 0.2 0.0 0.0 0.0 0.2 1.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.7 0.1 4.3 0.1 0.1 0.3 0.1 0.0 0.4 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 4.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 4.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.3 3.8 0.0 56.9 18.1 23.2 0.0 5.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 29.8 0.0 3.0 0.1 0.0 5.1 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.3 6.4 7.4 0.0 0.5 0.4 1.0 0.1 0.0 0.7 0.2 0.1 0.5 0.0 3.7 0.0 0.0 0.2 1.4 0.2 0.0 0.0 0.2 0.1 0.1 1.9 0.0 0.0 0.7 0.0 0.2 1.5 0.0 0.3 7.6 0.2 0.7 0.0 2.4 0.0 0.8 0.0 0.0 11.2 1.6 0.2 0.3 7.8 1.8 0.0 20.5 0.2 2.1 0.0 0.5 0.1 0.0 0.0 0.3 0.8 0.0 0.1 2.2 0.7 0.0 0.7 0.2 0.1 0.1 0.0 0.1 0.1 1.1 0.1 0.0 0.7 NLRP7 "CLR19.4, NALP7, NOD12, PAN7, PYPAF3" ENSG00000167634 "NLR family pyrin domain containing 7" Q8WX94 19 54923509-54966312 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 3.9" "Cell type enhanced" "Detected in some" "dendritic cells: 8.2;Early spermatids: 8.3;Extravillous trophoblasts: 5.7;Late spermatids: 14.8;Plasma cells: 5.2;Spermatocytes: 6.4;Spermatogonia: 5.6" "Cancer enriched" "Detected in many" 30 "testis cancer: 146.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "plasmacytoid DC: 3.9" "Lineage enriched" "Detected in single" 6 "dendritic cells: 3.9" "Cell line enhanced" "Detected in some" "BEWO: 1.9;RT4: 1.0;SuSa: 1.5;U-266/84: 5.0" HPA051382 Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 83: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 65: Plasmacytoid DCs - Unknown function" "Golgi apparatus" "HPA051382: AB_2681461" "unprognostic (2.15e-2)" "unprognostic (2.40e-2)" "unprognostic (1.68e-3)" "unprognostic (1.24e-2)" "unprognostic (5.29e-3)" "unprognostic (5.46e-2)" "unprognostic (1.13e-1)" "unprognostic (1.15e-1)" "unprognostic (5.01e-1)" "unprognostic (5.81e-2)" "unprognostic (1.27e-1)" "unprognostic (1.34e-1)" "unprognostic (3.25e-8)" "unprognostic (1.84e-1)" "unprognostic (1.18e-1)" "unprognostic (7.31e-3)" "unprognostic (4.45e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 2.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 8.2 0.0 0.0 0.0 8.3 0.3 0.0 0.0 0.0 0.0 0.9 0.0 5.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 14.8 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.4 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 5.6 0.0 0.0 1.9 0.3 0.0 0.0 0.6 NMRK1 "bA235O14.2, C9orf95, FLJ20559, NRK1" ENSG00000106733 "Nicotinamide riboside kinase 1" Q9NWW6 9 75060573-75088217 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 68.6;Karpas-707: 79.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049795 Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" Centrosome "HPA049795: AB_2680886" "unprognostic (1.12e-1)" "unprognostic (4.13e-2)" "unprognostic (3.58e-2)" "prognostic favorable (3.70e-6)" "unprognostic (3.56e-2)" "unprognostic (2.35e-1)" "unprognostic (5.20e-3)" "unprognostic (2.21e-2)" "unprognostic (3.27e-2)" "unprognostic (2.43e-1)" "unprognostic (2.06e-2)" "unprognostic (1.78e-1)" "prognostic favorable (5.60e-4)" "unprognostic (9.25e-2)" "unprognostic (1.76e-1)" "unprognostic (5.28e-2)" "unprognostic (5.64e-2)" 22.1 11.5 14.6 14.3 15.0 12.6 20.2 17.0 18.9 21.8 15.4 15.3 17.8 11.2 18.5 39.5 16.4 14.1 15.5 15.2 15.4 32.5 53.7 21.7 17.5 14.9 14.8 22.7 45.1 64.1 19.8 14.8 15.2 23.7 13.0 8.8 31.2 13.6 27.2 23.2 22.4 8.8 14.8 31.1 26.0 9.7 14.4 17.3 25.6 13.4 20.0 18.8 25.6 15.2 11.7 2.7 3.2 7.9 21.4 28.0 18.1 17.0 22.4 3.5 5.8 0.1 29.8 6.8 10.0 13.8 7.2 18.5 3.8 9.4 10.0 68.6 3.5 5.1 5.6 5.7 20.3 4.8 0.8 22.5 23.5 6.3 11.8 20.8 25.1 10.8 0.5 79.0 24.6 8.4 4.3 4.3 3.9 40.2 10.0 1.6 29.7 42.1 28.9 19.5 2.2 0.5 7.3 6.4 9.0 19.2 18.4 4.5 20.6 13.5 2.9 12.9 4.6 37.5 31.4 4.1 23.1 4.9 13.8 16.4 5.4 9.3 25.1 5.1 30.5 13.4 43.7 29.2 6.1 9.1 39.4 30.2 9.8 17.2 14.5 17.2 31.6 18.1 14.6 15.0 17.0 18.9 15.2 15.4 14.9 14.8 15.2 14.8 14.4 15.2 42.2 38.5 21.7 11.8 22.6 21.0 36.4 38.2 38.7 8.4 33.4 37.5 15.5 21.5 27.9 23.9 8.4 53.3 43.7 32.8 52.8 30.5 17.8 42.4 16.8 33.4 4.2 10.3 26.2 35.5 75.7 22.7 49.5 37.4 1.3 8.3 55.3 45.2 62.4 11.8 20.6 34.8 22.4 32.5 9.6 30.8 23.6 22.9 26.6 14.0 67.6 15.2 43.3 13.6 23.9 21.5 26.1 12.4 68.8 23.4 83.8 92.1 30.5 8.3 13.1 24.5 15.0 10.7 8.3 50.9 27.0 45.6 48.8 22.2 25.0 32.6 NNT ENSG00000112992 "Nicotinamide nucleotide transhydrogenase" Q13423 5 43602692-43707405 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Translocase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 239.1;tongue: 384.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 344.3;Hepatocytes: 314.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004829, CAB004975" Enhanced Approved Mitochondria,Cytosol NA NA 110000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria Cytosol "CAB004975: AB_425908, HPA004829: AB_1079495" "unprognostic (1.51e-1)" "unprognostic (1.07e-1)" "unprognostic (3.33e-2)" "unprognostic (4.81e-2)" "unprognostic (5.02e-2)" "unprognostic (1.81e-1)" "unprognostic (4.04e-2)" "unprognostic (1.96e-3)" "unprognostic (2.20e-2)" "unprognostic (3.98e-2)" "unprognostic (1.65e-1)" "unprognostic (8.33e-2)" "prognostic favorable (1.22e-15)" "unprognostic (8.24e-2)" "unprognostic (1.11e-1)" "unprognostic (2.76e-2)" "unprognostic (2.58e-1)" 26.0 16.5 12.8 11.8 16.0 15.0 13.7 11.2 21.7 16.4 34.9 25.9 17.2 11.0 16.7 16.8 10.7 15.0 137.7 16.1 11.5 57.0 116.4 13.2 16.5 10.3 12.0 10.1 17.8 55.6 9.6 12.7 9.5 18.3 27.8 12.9 26.6 18.2 239.1 10.4 16.1 20.6 9.3 11.5 31.2 6.2 15.8 26.8 31.1 384.0 17.2 17.3 9.3 15.1 15.4 12.6 30.5 59.6 44.0 50.3 9.9 17.5 39.8 24.8 20.8 19.0 30.4 18.5 21.5 43.9 22.3 16.6 120.5 5.4 27.4 31.1 33.6 24.0 70.7 23.8 27.5 50.2 43.1 37.9 17.5 16.3 18.6 42.6 56.3 22.7 21.4 81.3 60.0 15.1 55.8 35.8 6.4 0.1 15.2 54.7 73.8 70.8 58.0 15.5 44.2 37.7 62.9 1.4 46.7 6.9 47.7 58.3 23.2 29.5 28.3 12.0 8.3 36.1 45.1 26.5 7.1 68.8 22.1 12.5 18.2 16.0 16.7 23.0 17.1 12.0 17.1 15.5 32.0 12.0 15.5 14.7 2.9 23.2 24.7 9.1 22.2 19.3 12.8 16.0 11.2 21.7 16.1 11.5 10.3 12.0 9.5 9.3 15.8 15.1 12.0 54.5 37.8 60.7 19.6 11.5 9.5 19.0 13.1 17.9 9.6 6.3 344.3 38.6 27.0 27.6 35.5 8.7 20.4 34.4 27.4 14.4 16.7 18.5 16.6 19.2 19.9 34.9 124.8 10.7 2.3 27.2 23.9 25.1 25.2 26.8 21.0 314.3 25.0 6.7 110.6 22.6 20.3 40.6 11.9 4.6 14.9 19.8 14.2 45.9 25.9 12.5 35.0 77.9 63.4 9.5 16.7 19.2 20.0 11.7 23.6 21.7 18.1 12.8 0.0 14.0 20.1 4.0 1.4 17.6 8.1 2.1 20.9 18.8 28.9 9.9 NOD1 "CARD4, CLR7.1, NLRC1" ENSG00000106100 "Nucleotide binding oligomerization domain containing 1" Q9Y239 7 30424527-30478784 "Human disease related genes, Predicted intracellular proteins" "Apoptosis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 19.3;Microglial cells: 26.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 11.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA074367 Approved Mitochondria NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Mitochondria "HPA074367: AB_2686683" "unprognostic (2.58e-1)" "unprognostic (1.56e-2)" "unprognostic (9.73e-2)" "unprognostic (8.09e-3)" "unprognostic (2.07e-2)" "unprognostic (1.70e-1)" "unprognostic (1.01e-3)" "unprognostic (6.63e-2)" "unprognostic (2.26e-1)" "unprognostic (2.74e-1)" "unprognostic (8.78e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (6.68e-4)" "unprognostic (6.62e-2)" "unprognostic (1.46e-1)" "prognostic favorable (1.95e-4)" "unprognostic (2.64e-1)" 10.6 2.9 3.0 8.8 3.2 6.8 9.5 2.5 2.6 5.3 4.6 5.3 2.2 6.1 2.6 4.7 6.5 5.4 7.3 2.4 3.2 3.9 2.2 11.9 6.1 7.6 4.9 10.3 1.8 2.7 2.9 12.2 4.7 4.0 4.3 0.6 6.2 3.2 4.0 5.9 5.4 7.3 3.6 11.1 4.8 1.9 5.6 3.5 10.8 4.0 5.0 7.3 5.0 2.8 4.8 2.5 3.5 10.5 2.2 10.3 5.3 3.3 2.3 5.5 7.0 2.2 5.7 6.9 3.8 4.2 6.1 11.2 3.5 5.8 3.7 3.6 3.0 9.7 7.7 2.2 2.8 4.3 7.0 9.6 2.5 3.5 3.0 4.9 18.3 10.1 5.2 2.4 5.0 2.8 6.2 7.7 4.1 5.3 4.5 7.4 4.0 6.3 1.8 3.8 0.6 12.4 4.2 10.7 3.7 4.8 3.6 9.6 7.7 4.8 7.6 6.0 4.5 2.2 8.0 0.3 3.5 15.1 5.1 13.7 3.7 13.5 8.1 5.0 8.9 7.5 5.5 5.3 3.3 10.9 4.9 4.0 2.8 8.5 6.6 8.0 4.8 2.6 3.0 3.2 2.5 2.6 2.4 3.2 7.6 4.9 4.7 3.6 5.6 2.8 19.3 3.2 15.1 7.2 6.6 0.8 0.5 1.0 5.2 2.4 2.9 2.9 4.9 1.5 5.0 5.5 0.0 5.0 6.7 4.5 0.0 1.3 0.2 4.4 1.7 12.0 0.0 3.4 5.3 2.1 2.3 8.2 1.1 4.6 2.5 7.8 13.6 1.3 4.6 0.0 1.4 5.5 2.0 3.1 3.7 0.0 0.6 4.3 5.4 26.2 4.0 0.6 6.2 2.5 1.1 1.7 1.7 1.9 3.1 0.2 1.6 0.5 2.9 0.2 0.0 2.5 5.6 0.0 0.6 5.4 1.8 1.5 5.3 1.0 5.6 0.8 NOSIP CGI-25 ENSG00000142546 "Nitric oxide synthase interacting protein" Q9Y314 19 49555468-49590262 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 364.8;Late spermatids: 844.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043464, HPA062132" Approved Enhanced Nucleoplasm NA NA "Cluster 32: T-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA043464: AB_10794284, HPA062132: AB_2684693" "unprognostic (2.27e-1)" "unprognostic (4.69e-2)" "unprognostic (1.39e-1)" "unprognostic (4.17e-2)" "unprognostic (1.59e-2)" "unprognostic (9.46e-2)" "unprognostic (1.47e-2)" "unprognostic (9.42e-2)" "unprognostic (3.79e-1)" "unprognostic (1.25e-1)" "unprognostic (2.27e-2)" "unprognostic (9.73e-2)" "unprognostic (3.97e-2)" "unprognostic (2.15e-1)" "unprognostic (9.76e-2)" "unprognostic (1.02e-1)" "unprognostic (2.95e-3)" 42.4 48.0 33.2 27.1 37.0 31.7 42.8 37.2 45.1 50.0 29.4 49.0 29.1 49.3 10.0 47.8 45.1 15.4 60.9 31.9 35.0 48.1 48.6 39.5 51.8 36.2 34.9 44.5 125.1 24.0 40.8 21.6 36.9 44.0 14.6 10.1 38.3 20.6 134.7 46.7 50.8 16.2 34.7 63.2 44.8 143.5 36.0 40.0 40.9 65.2 26.5 41.3 41.7 38.0 239.7 114.5 49.6 113.1 43.5 32.7 44.5 54.8 50.0 90.9 85.3 84.9 43.1 63.4 93.5 48.2 37.0 51.0 47.8 98.4 40.3 74.1 126.0 81.3 67.9 96.6 66.6 67.8 64.6 43.4 66.5 71.4 37.7 38.0 54.4 101.8 90.7 46.0 50.3 59.7 66.2 127.0 65.9 89.3 100.4 89.3 74.0 58.3 43.5 70.6 57.4 71.2 74.9 59.1 50.2 21.8 53.9 72.6 83.5 83.6 64.4 27.0 99.3 87.8 186.7 86.6 31.2 90.7 65.2 261.9 129.1 192.3 257.3 126.1 328.8 161.8 519.8 294.6 127.8 157.2 841.3 466.7 244.1 244.5 117.6 168.8 303.6 579.4 33.2 37.0 37.2 45.1 31.9 35.0 36.2 34.9 36.9 34.7 36.0 38.0 78.3 19.2 34.9 13.1 67.3 72.8 54.8 109.8 40.9 25.4 45.5 49.5 38.4 62.9 59.3 51.5 22.9 94.2 74.7 171.6 86.1 84.5 364.8 56.3 44.9 73.0 58.7 58.5 9.2 283.6 85.0 51.7 57.6 68.6 68.4 57.0 93.9 49.5 72.2 11.8 9.1 108.9 91.6 63.8 67.0 844.8 71.7 55.5 62.2 13.1 100.5 45.5 120.5 9.0 12.3 219.2 138.2 72.2 55.4 43.2 129.6 133.8 58.4 37.2 59.2 85.1 66.1 268.7 50.9 39.6 76.3 136.3 154.2 73.1 108.5 54.4 NOSTRIN MGC20702 ENSG00000163072 "Nitric oxide synthase trafficking" Q8IVI9 2 168786539-168865514 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 167.0;Endothelial cells: 129.6;Hepatic stellate cells: 172.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 10.1;HEL: 41.9;K-562: 31.8;OE19: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044384, HPA076885" Approved Approved Vesicles,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol Vesicles "HPA044384: AB_2678922, HPA076885: " "unprognostic (4.74e-2)" "unprognostic (2.42e-1)" "unprognostic (8.73e-2)" "unprognostic (2.27e-1)" "unprognostic (3.15e-3)" "unprognostic (3.02e-6)" "unprognostic (4.89e-3)" "unprognostic (3.15e-1)" "unprognostic (3.14e-4)" "unprognostic (5.47e-3)" "unprognostic (1.19e-1)" "unprognostic (2.51e-1)" "unprognostic (1.63e-1)" "unprognostic (1.75e-1)" "unprognostic (2.33e-1)" "unprognostic (6.47e-2)" "unprognostic (4.98e-2)" 32.6 20.4 6.1 4.6 5.8 0.3 31.4 5.0 7.6 17.5 4.2 15.3 14.0 14.9 4.3 5.1 16.4 14.0 16.1 4.9 5.6 32.6 7.3 30.8 4.6 6.6 6.0 10.6 22.6 3.8 3.8 25.4 6.5 13.3 16.4 0.8 48.9 6.8 5.1 7.3 14.3 12.8 5.5 5.5 23.0 14.4 6.6 1.9 13.5 3.6 3.0 8.1 11.3 5.0 0.0 3.6 1.1 0.0 0.0 0.0 10.1 0.4 0.0 0.0 0.0 6.3 6.5 0.1 4.3 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.0 41.9 1.8 0.0 0.2 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 31.8 0.0 0.0 0.1 0.1 0.1 0.1 20.5 0.3 0.4 1.9 0.0 3.4 1.6 0.0 0.1 0.2 1.9 0.0 0.2 0.5 0.0 0.0 0.0 0.7 0.2 0.6 0.6 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 5.8 5.0 7.6 4.9 5.6 6.6 6.0 6.5 5.5 6.6 5.0 167.0 9.6 10.3 2.0 1.6 1.0 0.6 0.3 0.6 0.1 20.0 11.0 7.1 15.7 3.3 3.7 0.0 18.9 0.4 57.3 13.7 8.0 26.6 16.3 3.3 129.6 11.4 2.7 0.4 21.8 7.0 6.1 41.3 23.2 0.0 72.4 172.5 1.0 1.6 0.0 0.5 35.9 0.0 6.3 0.9 60.9 8.7 1.2 24.9 55.3 0.7 1.6 0.0 2.0 0.0 17.7 53.4 5.7 0.2 3.3 43.1 59.0 1.5 0.3 72.3 1.3 11.3 13.7 1.8 0.4 0.4 26.3 0.9 71.9 20.7 1.2 NOVA1 NOVA-1 ENSG00000139910 "NOVA alternative splicing regulator 1" P51513 14 26443090-26598033 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 222.9;Excitatory neurons: 414.9;Oligodendrocyte precursor cells: 1269.7;Oligodendrocytes: 319.5" "Cancer enriched" "Detected in many" 5 "glioma: 14.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 53.3;ASC diff: 25.6;HAP1: 23.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004155 Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoli Nucleoplasm "HPA004155: AB_1079497" "unprognostic (1.46e-1)" "unprognostic (4.43e-3)" "unprognostic (6.55e-3)" "unprognostic (4.00e-2)" "unprognostic (6.69e-3)" "unprognostic (4.29e-2)" "unprognostic (3.74e-3)" "unprognostic (2.41e-1)" "unprognostic (5.21e-1)" "unprognostic (4.32e-2)" "unprognostic (5.04e-4)" "unprognostic (2.40e-1)" "unprognostic (1.93e-3)" "unprognostic (9.27e-4)" "unprognostic (9.20e-2)" "unprognostic (5.62e-2)" "unprognostic (1.31e-4)" 23.4 5.4 44.0 2.4 39.7 0.1 28.9 85.4 56.3 12.1 18.9 11.6 1.4 8.5 4.9 2.9 6.7 4.8 3.3 38.8 65.3 6.1 0.9 1.4 3.4 50.3 51.2 5.0 1.2 2.4 19.3 0.1 48.5 5.6 5.1 13.4 2.7 15.9 4.3 4.7 3.6 9.5 49.2 0.9 3.3 8.8 71.1 1.2 3.4 8.7 4.5 5.9 8.4 45.5 0.0 11.6 53.3 0.0 25.6 14.6 0.1 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.7 0.7 7.1 0.1 23.7 0.2 0.0 0.0 1.8 0.0 0.1 0.3 8.5 0.0 2.1 16.8 0.0 3.6 2.9 17.8 10.3 8.7 0.0 0.1 8.4 0.0 9.8 0.1 13.5 0.0 10.9 1.3 14.8 0.2 6.8 9.1 15.5 9.4 0.0 0.0 0.0 4.2 1.1 0.0 0.0 6.5 7.7 5.2 1.4 0.0 0.0 0.0 8.8 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 44.0 39.7 85.4 56.3 38.8 65.3 50.3 51.2 48.5 49.2 71.1 45.5 24.8 0.0 1.5 141.0 0.2 5.2 5.9 0.0 4.6 222.9 51.5 29.6 1.1 5.7 0.0 14.7 4.2 0.1 1.4 6.6 9.8 0.4 20.1 0.6 15.0 9.4 65.9 0.0 414.9 0.4 0.0 188.8 0.5 0.2 0.0 18.2 38.6 0.5 0.2 136.3 203.5 7.1 0.0 0.6 10.5 16.5 150.4 2.1 3.6 93.7 0.0 32.3 0.0 1269.7 319.5 2.0 11.7 65.8 1.9 6.7 0.3 30.3 4.4 12.0 6.6 28.6 17.7 163.1 64.3 0.7 3.1 0.0 1.5 30.0 8.4 0.6 NPNT "EGFL6L, POEM" ENSG00000168743 Nephronectin Q6UXI9 4 105894775-106004027 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 137.0;thyroid gland: 234.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 185.9;Alveolar cells type 2: 103.7;Club cells: 56.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 104.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 30.9;CAPAN-2: 19.1;HeLa: 32.3;Hep G2: 27.1;MCF7: 24.3;RPTEC TERT1: 37.7;T-47d: 51.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003711, HPA050203" Supported Approved "Nucleoplasm,Cell Junctions,Cytosol" "Secreted to extracellular matrix" NA NA 120000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Cell Junctions, Cytosol" "HPA003711: AB_1854591, HPA050203: AB_2681050" "unprognostic (1.24e-1)" "unprognostic (7.93e-2)" "unprognostic (1.59e-1)" "unprognostic (2.43e-2)" "unprognostic (3.92e-1)" "unprognostic (2.49e-1)" "unprognostic (1.87e-1)" "unprognostic (7.85e-3)" "unprognostic (4.78e-4)" "unprognostic (1.19e-2)" "unprognostic (1.57e-1)" "unprognostic (1.68e-1)" "prognostic favorable (8.28e-8)" "unprognostic (4.81e-2)" "unprognostic (1.21e-1)" "unprognostic (1.77e-1)" "unprognostic (2.31e-2)" 22.8 6.3 9.7 5.6 7.9 0.2 27.0 4.7 8.0 32.4 5.7 24.5 56.1 20.9 22.2 10.9 22.4 30.5 5.2 7.5 14.6 105.0 4.0 137.0 4.5 6.1 31.8 10.9 40.1 1.0 47.4 3.4 9.2 82.9 25.2 2.4 8.9 18.7 4.9 8.2 74.1 14.1 4.4 14.8 14.9 3.1 10.5 14.2 234.5 11.5 5.4 9.7 22.1 6.6 0.0 0.2 0.3 0.6 0.0 0.0 30.9 0.2 0.1 0.0 0.0 14.9 19.1 0.2 0.8 0.2 0.0 1.7 7.4 0.0 0.0 0.0 8.4 0.8 32.3 27.1 0.1 0.0 0.2 3.2 2.4 0.0 0.0 0.3 0.0 0.4 0.1 0.4 0.0 24.3 0.4 1.5 0.3 0.1 12.0 0.0 0.1 0.3 37.7 1.6 1.7 0.6 1.8 14.1 0.0 4.1 51.2 1.3 0.0 0.6 0.4 0.5 1.1 0.3 1.1 0.0 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 7.9 4.7 8.0 7.5 14.6 6.1 31.8 9.2 4.4 10.5 6.6 5.2 185.9 103.7 15.3 0.0 1.9 5.2 13.1 1.8 1.1 22.2 7.0 2.5 27.1 56.4 33.1 0.0 2.4 0.7 5.9 1.9 24.7 11.0 1.0 1.5 18.4 15.6 0.0 1.0 2.5 0.2 8.3 1.1 1.9 0.0 3.3 2.9 0.3 0.3 0.0 10.0 10.6 4.1 0.0 1.5 15.4 2.5 0.6 5.4 14.0 0.0 0.0 0.0 2.0 0.3 7.5 3.4 0.0 0.0 28.4 19.6 4.3 6.4 0.2 0.0 1.9 26.4 2.4 2.0 3.6 1.1 1.5 0.3 1.5 11.0 5.7 NPR1 "ANPa, ANPRA, GUCY2A, NPRA" ENSG00000169418 "Natriuretic peptide receptor 1" P16066 1 153678688-153693992 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis" "Lyase, Receptor, Vasoactive" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 67.1" "Group enriched" "Detected in many" 6 "Adipocytes: 99.6;Endothelial cells: 52.5;Hepatic stellate cells: 132.8" "Group enriched" "Detected in all" 4 "ovarian cancer: 39.2;renal cancer: 12.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "ASC diff: 158.5" "Region enriched" "Detected in all" 5 "olfactory bulb: 18.7" "Low region specificity" "Detected in many" HPA031087 Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoli "Nucleoplasm, Plasma membrane" "HPA031087: AB_10601975" "unprognostic (2.54e-1)" "unprognostic (3.03e-3)" "unprognostic (6.31e-2)" "prognostic unfavorable (3.97e-4)" "unprognostic (1.55e-1)" "unprognostic (6.60e-2)" "unprognostic (1.54e-2)" "unprognostic (2.03e-1)" "unprognostic (2.46e-1)" "unprognostic (3.27e-2)" "prognostic favorable (2.49e-4)" "unprognostic (1.27e-1)" "unprognostic (6.69e-2)" "unprognostic (1.16e-2)" "unprognostic (1.09e-1)" "unprognostic (4.06e-1)" "unprognostic (1.74e-2)" 67.1 8.7 1.7 3.4 1.5 0.0 44.3 1.4 1.4 8.8 1.5 10.1 1.5 31.0 5.5 4.3 36.4 5.9 15.8 1.3 1.4 28.8 4.3 24.2 2.3 1.5 1.5 27.7 3.9 8.4 3.8 17.7 1.5 4.4 2.0 0.1 3.7 12.1 7.2 6.6 9.3 9.7 1.8 2.2 8.8 1.3 2.4 1.9 14.0 11.1 1.3 12.8 9.7 1.4 0.0 1.3 0.1 0.0 158.5 0.6 0.1 0.0 0.0 0.1 0.1 0.1 0.6 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 28.0 0.0 19.0 0.0 0.0 0.3 0.0 0.3 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 15.9 0.0 0.0 2.1 0.0 0.1 0.0 1.9 0.0 5.7 1.0 0.1 0.0 0.2 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.5 1.4 1.4 1.3 1.4 1.5 1.5 1.5 1.8 2.4 1.4 99.6 0.0 6.9 0.0 0.2 1.5 0.5 0.0 0.6 0.0 0.5 0.5 4.5 2.8 0.0 14.7 0.0 0.2 0.1 0.0 0.0 0.7 9.1 6.2 8.8 52.5 0.0 0.0 0.0 0.0 1.3 15.2 0.0 15.4 0.0 0.0 132.8 2.4 0.3 0.0 0.0 0.0 0.0 4.7 4.0 11.5 10.2 0.5 0.0 0.0 5.2 0.0 0.0 0.0 0.0 1.0 0.0 4.1 0.0 0.5 0.0 4.0 0.0 0.0 0.0 1.4 2.2 0.5 0.1 0.2 1.0 0.7 0.3 1.4 0.2 0.0 NR2F2 "ARP1, COUP-TFII, COUPTF2, COUPTFB, NF-E3, SVP40, TFCOUP2" ENSG00000185551 "Nuclear receptor subfamily 2 group F member 2" P24468 15 96325938-96340263 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 292.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 542.2;Hepatic stellate cells: 395.5;Leydig cells: 510.4;Peritubular cells: 610.5;Sertoli cells: 486.4;Smooth muscle cells: 385.7;Theca cells: 572.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058974 Approved Nucleoplasm,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "HPA058974: AB_2732629" "unprognostic (9.28e-2)" "unprognostic (2.52e-2)" "unprognostic (2.34e-1)" "unprognostic (1.42e-2)" "unprognostic (8.96e-2)" "unprognostic (5.44e-2)" "unprognostic (3.38e-1)" "unprognostic (1.14e-1)" "unprognostic (2.61e-1)" "unprognostic (1.87e-1)" "unprognostic (1.89e-1)" "unprognostic (9.19e-2)" "unprognostic (5.14e-2)" "unprognostic (5.96e-2)" "unprognostic (1.72e-2)" "unprognostic (7.47e-2)" "unprognostic (1.28e-2)" 95.5 43.1 32.7 18.8 19.2 0.1 59.7 15.0 19.6 128.6 23.5 52.6 21.5 120.9 61.8 22.1 101.5 65.7 44.4 20.0 24.8 79.8 32.1 56.8 42.4 16.2 21.9 292.4 20.0 30.7 20.3 74.7 18.2 60.6 26.7 2.5 22.9 126.4 33.1 24.1 32.1 81.8 12.5 106.2 82.3 26.7 49.3 7.8 46.2 31.5 15.1 46.3 74.5 10.7 154.7 39.1 125.6 78.5 249.1 85.5 41.9 109.1 83.2 111.1 94.3 134.8 153.4 0.1 86.8 55.2 44.1 90.4 22.3 78.3 138.8 0.5 86.5 49.9 48.7 24.6 69.5 38.7 18.0 61.3 26.5 92.5 19.8 130.5 207.3 0.1 135.3 0.4 71.2 105.5 0.1 27.6 1.2 59.6 52.7 0.1 30.9 0.2 244.7 165.7 15.8 0.2 12.3 3.7 17.5 55.0 61.1 2.8 215.3 119.9 39.7 28.3 38.8 0.1 0.4 0.4 67.0 18.9 85.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.7 19.2 15.0 19.6 20.0 24.8 16.2 21.9 18.2 12.5 49.3 10.7 133.4 28.9 18.1 0.7 1.1 14.4 24.9 71.7 39.3 7.5 51.9 50.8 46.4 203.0 34.6 62.5 25.0 126.2 2.0 35.7 46.9 22.0 3.2 70.9 542.2 166.1 26.4 5.3 0.1 10.9 50.3 125.8 80.0 68.9 0.0 41.5 395.5 51.6 10.3 3.3 24.8 35.5 32.6 12.2 20.1 22.9 510.4 5.0 26.6 36.5 0.6 30.2 0.0 0.0 0.5 15.6 23.9 610.5 2.8 22.3 14.3 65.5 37.3 13.8 486.4 27.8 385.7 6.4 7.9 20.5 10.4 35.3 5.8 572.5 27.1 21.3 NREP "C5orf13, D4S114, P311, PRO1873, PTZ17, SEZ17" ENSG00000134986 "Neuronal regeneration related protein" Q16612 5 111662621-111997464 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 118.3;Excitatory neurons: 116.1;Theca cells: 150.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "myeloid DC: 24.6;NK-cell: 6.9;plasmacytoid DC: 25.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 425.3;SH-SY5Y: 461.8" "Region enriched" "Detected in all" 5 "cerebellum: 1766.0" "Region enhanced" "Detected in all" "cerebellum: 219.5" HPA000545 Approved Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA000545: AB_1845721" "unprognostic (2.85e-2)" "unprognostic (1.00e-2)" "unprognostic (2.30e-1)" "unprognostic (1.48e-3)" "unprognostic (4.37e-1)" "unprognostic (2.26e-1)" "unprognostic (8.16e-3)" "unprognostic (1.58e-1)" "unprognostic (6.45e-3)" "unprognostic (1.32e-1)" "unprognostic (3.76e-2)" "unprognostic (2.02e-1)" "unprognostic (4.44e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (2.84e-2)" "unprognostic (3.47e-3)" "unprognostic (5.76e-3)" 18.9 56.5 50.1 19.4 52.6 36.7 29.3 141.8 71.6 32.3 56.9 28.6 16.9 84.8 17.9 23.0 18.2 65.4 70.9 52.5 44.0 49.5 50.7 27.7 17.3 47.8 52.1 41.8 9.8 8.4 13.3 119.8 50.8 52.7 25.2 107.4 36.1 72.2 179.9 22.1 16.7 54.6 44.6 36.9 25.7 12.7 46.4 168.1 18.6 118.2 18.4 27.5 16.8 54.7 0.6 7.1 425.3 91.5 20.2 46.6 20.3 140.9 83.9 135.7 221.0 0.8 2.8 73.1 44.6 71.3 18.9 0.3 91.0 5.2 69.4 29.5 13.0 57.5 35.2 77.6 28.1 77.0 0.8 45.6 22.5 129.5 44.5 318.6 154.2 81.4 0.6 7.4 143.4 1.6 308.3 53.7 244.1 0.2 33.3 326.3 173.4 19.9 52.2 1.6 96.9 461.8 31.6 2.2 2.9 224.2 17.7 210.6 31.1 163.7 54.1 80.8 15.8 34.6 29.3 92.3 35.6 159.8 32.8 0.0 4.0 0.0 0.0 2.2 0.0 1.6 0.1 0.2 24.6 1.1 1.2 1.6 0.1 6.9 1.0 25.1 0.0 2.2 50.1 52.6 141.8 71.6 52.5 44.0 47.8 52.1 50.8 44.6 46.4 54.7 20.8 6.4 30.8 43.1 3.6 18.1 1.6 4.5 14.2 66.9 12.4 22.6 33.4 8.6 5.7 12.9 87.6 118.3 12.9 2.5 33.2 14.4 2.5 5.4 69.1 38.9 21.6 52.2 116.1 5.5 18.6 31.7 31.1 7.4 5.1 69.9 27.5 10.1 35.5 20.2 51.4 9.3 42.7 10.0 19.0 1.0 8.4 14.9 14.2 17.8 11.5 14.9 5.2 37.2 4.6 8.2 2.0 23.3 0.9 0.7 1.2 61.0 0.5 29.0 13.1 25.4 51.8 0.8 12.6 11.9 12.6 31.5 3.2 150.8 11.3 0.2 NRP2 VEGF165R2 ENSG00000118257 "Neuropilin 2" O60462 2 205681990-205798133 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 78.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 134.4;Hepatic stellate cells: 137.8;Hofbauer cells: 141.3;Langerhans cells: 129.8;monocytes: 224.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 123.6;HUVEC TERT2: 105.7;TIME: 106.3;U-251 MG: 217.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039980, HPA054974" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted in other tissues" NA NA 29000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA039980: AB_10795517, HPA054974: AB_2682657" "unprognostic (4.28e-2)" "unprognostic (1.17e-1)" "unprognostic (8.12e-3)" "unprognostic (3.38e-1)" "unprognostic (1.62e-1)" "unprognostic (1.57e-2)" "unprognostic (9.36e-2)" "unprognostic (3.70e-1)" "unprognostic (2.15e-3)" "unprognostic (2.90e-2)" "unprognostic (2.56e-3)" "unprognostic (4.17e-1)" "prognostic unfavorable (7.68e-7)" "unprognostic (2.22e-3)" "unprognostic (5.45e-2)" "unprognostic (6.41e-3)" "prognostic unfavorable (7.80e-5)" 18.8 22.2 18.0 17.8 13.8 4.6 12.6 9.3 11.7 18.8 7.0 78.7 5.3 51.8 3.7 13.3 21.1 31.1 6.3 21.7 42.5 4.9 9.6 24.3 8.2 30.4 23.9 46.8 1.9 2.5 9.6 47.0 19.6 13.0 10.5 3.6 3.3 30.9 2.3 4.8 14.9 54.8 13.2 7.5 25.9 1.4 33.9 6.1 10.8 3.4 4.5 38.3 15.9 12.4 2.5 50.4 32.2 0.2 30.1 9.6 9.3 8.5 14.8 10.0 9.5 48.0 123.6 0.0 11.9 25.3 20.5 19.2 1.5 15.9 16.8 0.1 6.8 0.5 2.4 0.4 80.7 0.0 2.1 68.5 12.2 14.4 12.3 64.5 105.7 0.2 0.2 0.1 6.8 0.2 0.0 0.0 41.5 0.1 9.2 0.2 2.0 12.0 21.7 0.0 29.0 1.0 1.1 0.3 75.4 84.9 0.1 0.8 106.3 43.1 0.4 11.3 217.0 0.0 0.2 3.2 96.9 0.3 88.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.0 13.8 9.3 11.7 21.7 42.5 30.4 23.9 19.6 13.2 33.9 12.4 88.7 89.8 57.5 2.0 3.8 19.4 19.5 30.8 97.9 36.5 1.3 11.3 4.5 5.7 53.2 1.8 0.0 89.7 0.1 0.6 0.0 6.4 6.3 8.8 8.1 134.4 1.2 2.7 4.1 3.8 8.7 47.0 1.5 13.2 3.8 2.7 137.8 1.8 141.3 0.0 9.4 1.1 4.1 28.0 129.8 18.9 2.8 53.7 19.6 53.4 224.8 4.8 0.0 4.0 8.1 53.2 0.0 4.9 0.2 9.1 0.0 0.6 48.1 2.7 0.0 4.6 32.2 1.4 1.4 17.8 12.6 25.7 2.4 48.1 0.4 51.5 NT5DC2 FLJ12442 ENSG00000168268 "5'-nucleotidase domain containing 2" Q9H857 3 52524385-52535054 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 69.2;Peritubular cells: 135.4;Sertoli cells: 111.7;Smooth muscle cells: 83.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050683 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 48: Smooth muscle cells - ECM organization" "HPA050683: AB_2681215" "unprognostic (1.40e-1)" "unprognostic (1.43e-1)" "unprognostic (1.92e-1)" "unprognostic (2.99e-2)" "unprognostic (7.82e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (6.14e-2)" "unprognostic (1.35e-1)" "unprognostic (5.15e-2)" "unprognostic (1.05e-1)" "unprognostic (1.11e-1)" "unprognostic (2.99e-3)" "unprognostic (1.44e-1)" "unprognostic (2.30e-1)" "unprognostic (1.50e-1)" "unprognostic (2.07e-2)" 30.3 73.2 26.0 18.6 25.2 15.5 27.9 38.6 29.8 48.0 43.2 18.3 13.7 36.3 27.5 69.4 29.5 12.1 117.5 26.0 30.2 30.6 7.8 33.6 16.3 41.8 46.6 45.3 15.6 16.5 50.8 32.7 64.0 74.9 12.7 8.5 43.5 39.3 10.3 49.0 16.2 20.8 26.8 18.6 16.4 49.7 27.6 9.9 26.3 10.9 22.9 40.7 38.7 25.9 138.8 73.7 238.9 128.4 186.2 252.3 188.3 139.6 121.2 95.4 78.0 216.5 66.8 174.4 15.1 177.9 76.0 47.3 194.9 179.8 90.0 71.0 123.8 104.1 122.1 337.4 274.9 0.1 88.8 333.0 40.9 162.9 49.4 175.4 203.0 125.2 194.9 57.5 112.0 145.5 72.7 179.2 318.1 125.6 234.6 104.6 100.3 168.8 52.7 35.5 111.1 323.3 54.7 101.2 71.8 178.6 96.0 98.5 95.1 123.7 153.8 123.8 298.9 25.9 47.3 129.4 369.4 0.7 152.1 0.0 0.3 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.1 0.0 1.1 0.0 0.1 26.0 25.2 38.6 29.8 26.0 30.2 41.8 46.6 64.0 26.8 27.6 25.9 20.9 9.6 11.5 2.6 12.9 7.8 26.6 15.2 30.1 18.4 54.6 69.2 14.0 5.7 13.0 12.9 0.0 3.4 3.3 3.1 17.6 10.1 6.9 5.3 20.0 12.6 12.6 8.0 0.9 2.3 24.8 24.8 8.6 10.8 18.4 36.4 11.0 1.2 10.4 1.7 1.2 6.0 10.2 10.1 8.8 19.7 49.7 7.8 16.0 1.9 2.8 36.6 1.0 5.0 1.5 7.0 0.6 135.4 21.4 23.4 0.6 9.3 2.7 4.7 111.7 18.6 83.4 6.2 37.9 23.5 13.8 2.3 2.8 15.8 7.2 12.7 NUBPL "C14orf127, FLJ12660, huInd1, IND1" ENSG00000151413 "Nucleotide binding protein like" Q8TB37 14 31489956-31861224 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 68.2;Inhibitory neurons: 74.8;Oligodendrocyte precursor cells: 87.9;Oligodendrocytes: 99.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029203 Approved Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA029203: AB_10602810" "unprognostic (1.49e-1)" "unprognostic (1.71e-2)" "unprognostic (5.21e-3)" "unprognostic (8.28e-2)" "unprognostic (8.25e-2)" "unprognostic (1.94e-3)" "unprognostic (1.67e-1)" "unprognostic (1.93e-2)" "unprognostic (1.15e-1)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" "unprognostic (2.80e-1)" "prognostic favorable (3.64e-8)" "unprognostic (2.82e-2)" "unprognostic (6.60e-2)" "unprognostic (3.67e-3)" "unprognostic (1.56e-2)" 9.7 6.4 4.2 3.9 4.6 1.8 8.9 4.5 4.8 4.9 4.2 7.6 4.9 5.8 7.6 4.6 6.4 5.3 17.0 4.0 5.0 12.2 12.3 4.1 5.7 4.9 4.7 6.8 5.5 7.9 3.8 5.5 4.5 6.3 7.8 5.2 11.9 6.1 11.9 4.7 5.8 5.4 4.3 6.6 4.7 3.5 5.0 5.5 8.0 17.4 5.4 4.2 3.2 5.8 13.6 8.5 6.4 3.3 8.9 16.4 11.5 7.3 8.2 8.9 10.2 5.9 15.3 9.8 9.2 9.1 7.5 11.7 8.6 15.5 15.3 7.1 11.1 3.5 6.3 30.4 8.8 10.4 3.0 10.7 17.0 6.0 12.8 7.3 5.0 7.0 6.4 4.9 9.8 7.4 7.7 7.1 5.4 10.8 13.1 8.6 13.4 5.3 10.2 10.0 6.0 6.2 12.2 10.8 14.5 7.2 21.1 5.4 4.9 8.6 5.9 5.6 6.8 8.1 9.7 9.3 5.5 7.3 7.9 0.0 1.1 0.4 2.1 1.2 1.7 2.6 2.7 2.3 4.4 1.7 3.0 2.4 0.4 2.5 0.7 2.2 1.8 0.9 4.2 4.6 4.5 4.8 4.0 5.0 4.9 4.7 4.5 4.3 5.0 5.8 6.9 12.8 9.8 68.2 10.1 9.6 8.6 5.4 9.1 15.3 10.2 7.1 36.9 15.7 10.6 9.2 20.9 11.2 7.5 6.3 7.9 6.8 24.1 12.6 10.8 6.3 7.2 6.7 48.2 5.7 10.2 12.0 7.1 5.4 14.5 16.4 4.6 15.3 4.9 10.1 74.8 12.0 2.0 4.1 16.1 7.4 6.5 6.1 12.4 54.4 2.8 16.2 5.2 87.9 99.6 5.2 5.8 11.7 8.0 4.4 5.1 19.1 18.7 28.4 13.1 11.8 9.8 15.7 5.2 7.3 11.6 5.7 6.4 23.1 18.2 5.9 NUCKS1 NUCKS ENSG00000069275 "Nuclear casein kinase and cyclin dependent kinase substrate 1" Q9H1E3 1 205712822-205750182 "Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062351, HPA063843" Supported Supported Nucleoplasm,Nucleoli No No 13000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm Nucleoli "HPA062351: AB_2684745, HPA063843: AB_2685134" "unprognostic (1.68e-1)" "unprognostic (3.92e-1)" "unprognostic (3.38e-1)" "prognostic unfavorable (1.41e-4)" "unprognostic (1.87e-1)" "unprognostic (2.93e-1)" "unprognostic (9.20e-2)" "unprognostic (1.79e-1)" "unprognostic (1.47e-2)" "unprognostic (5.16e-3)" "unprognostic (1.18e-3)" "unprognostic (1.37e-1)" "unprognostic (5.82e-3)" "unprognostic (7.45e-3)" "unprognostic (1.44e-1)" "unprognostic (2.25e-2)" "unprognostic (7.57e-2)" 63.3 57.2 88.6 43.3 98.3 33.4 72.8 86.2 102.7 70.8 53.7 52.5 29.5 83.4 62.0 54.4 71.8 46.7 98.3 80.7 88.8 70.4 104.2 48.7 61.2 93.8 87.8 108.9 41.2 96.1 39.0 49.6 94.1 71.7 48.1 81.4 46.8 71.1 113.7 51.4 33.2 69.8 94.6 56.5 43.0 25.8 87.9 97.4 98.1 101.6 60.7 47.8 45.2 115.8 223.5 134.6 354.2 140.8 96.0 131.7 166.1 157.3 161.3 215.6 172.6 74.4 250.0 246.1 89.0 154.2 68.2 160.0 272.6 131.9 245.7 118.6 135.8 160.3 113.2 81.8 70.6 255.0 54.9 105.1 116.9 128.6 221.7 115.6 171.4 156.3 261.9 76.7 170.7 258.1 233.2 128.0 363.0 88.9 99.4 239.1 436.4 141.1 121.4 135.4 146.9 270.9 232.2 183.3 127.5 272.4 280.3 189.9 172.8 164.5 144.8 190.0 282.8 69.9 88.0 192.6 112.8 140.5 226.2 5.6 3.2 3.9 9.1 4.9 8.8 5.6 8.3 8.0 4.6 6.9 10.1 10.7 0.6 10.7 4.2 7.3 5.5 3.8 88.6 98.3 86.2 102.7 80.7 88.8 93.8 87.8 94.1 94.6 87.9 115.8 258.4 214.7 283.4 73.4 179.5 258.1 277.4 212.9 282.9 356.2 221.2 229.7 412.4 318.8 241.8 303.5 73.0 301.5 174.5 125.5 385.4 202.5 61.3 227.0 410.3 254.5 179.0 324.2 85.9 171.5 381.3 356.5 131.0 299.5 215.4 329.0 258.5 668.2 264.1 316.3 88.7 219.2 116.0 216.8 266.4 52.6 512.0 164.0 174.3 71.2 162.1 546.9 195.7 56.8 126.2 117.2 113.2 485.2 128.2 295.3 49.4 384.5 187.8 200.2 315.5 458.0 358.1 70.0 104.1 321.4 243.9 177.2 190.5 443.9 265.1 220.8 NUDCD2 "DKFZp686E10109, NudCL2" ENSG00000170584 "NudC domain containing 2" Q8WVJ2 5 163446526-163460102 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037384, HPA037385" Uncertain Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA 18000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Microtubules "Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA037384: AB_2675447, HPA037385: AB_10673630" "unprognostic (3.96e-1)" "unprognostic (3.69e-2)" "prognostic favorable (2.80e-4)" "unprognostic (1.46e-1)" "unprognostic (9.12e-2)" "unprognostic (3.75e-3)" "unprognostic (1.84e-1)" "unprognostic (4.74e-1)" "unprognostic (3.47e-2)" "unprognostic (7.63e-3)" "unprognostic (1.81e-1)" "unprognostic (2.45e-1)" "unprognostic (3.91e-2)" "unprognostic (1.34e-2)" "unprognostic (6.86e-2)" "unprognostic (3.40e-2)" "unprognostic (7.85e-2)" 13.9 11.8 11.1 13.2 13.2 11.7 11.2 13.2 14.0 8.1 10.2 11.2 14.5 10.2 6.4 12.8 9.7 5.7 8.3 11.0 11.4 11.7 15.3 8.7 15.1 12.8 12.6 8.9 15.4 6.8 9.3 10.3 13.7 8.9 6.1 7.3 14.0 3.6 20.9 10.7 13.3 6.3 12.8 12.8 11.8 10.4 12.5 8.1 9.4 5.0 9.8 9.2 10.3 17.7 62.3 32.3 23.5 37.1 14.1 10.4 31.3 24.6 7.0 8.7 13.9 28.6 46.3 35.5 57.5 4.0 39.8 30.6 12.6 13.9 10.7 70.6 36.6 32.4 42.0 26.4 15.3 37.3 35.3 3.8 7.7 8.4 12.1 12.3 9.8 39.1 35.1 42.6 8.9 25.2 55.1 80.9 25.8 18.4 35.2 45.7 39.2 63.0 8.0 14.3 59.6 33.6 38.7 24.7 66.3 13.8 47.2 37.8 21.9 29.4 43.8 32.6 56.7 35.0 63.8 61.5 34.2 63.2 31.4 49.9 48.3 32.5 60.2 59.8 76.5 91.7 84.0 71.8 68.0 68.0 88.7 79.0 6.2 83.8 51.5 81.1 83.5 69.1 11.1 13.2 13.2 14.0 11.0 11.4 12.8 12.6 13.7 12.8 12.5 17.7 58.0 28.9 23.8 9.1 47.5 59.4 54.9 92.6 42.7 30.7 70.4 88.6 43.1 35.8 53.1 38.6 22.9 118.7 43.8 25.4 148.7 63.6 95.1 57.6 44.1 47.4 43.8 78.4 18.8 64.0 55.8 48.6 32.1 38.3 31.6 35.7 36.0 55.1 69.8 10.1 14.0 45.3 87.5 41.8 42.7 24.5 51.6 35.7 49.8 11.2 46.4 51.4 52.5 11.1 36.0 59.9 33.6 51.1 55.5 95.2 31.5 112.5 65.1 38.2 39.5 51.3 46.5 87.6 44.2 56.0 67.6 56.8 48.3 64.8 68.6 59.3 NUDT6 "FGF-AS, FGF2AS, gfg, gfg-1" ENSG00000170917 "Nudix hydrolase 6" P53370 4 122888697-122922968 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 27.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 37.2;Early spermatids: 36.7;Proximal tubular cells: 46.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039202, HPA066115" Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA039202: AB_10795032, HPA066115: AB_2685620" "unprognostic (7.51e-2)" "unprognostic (1.59e-1)" "unprognostic (1.46e-3)" "unprognostic (1.97e-2)" "unprognostic (3.11e-1)" "unprognostic (3.84e-2)" "unprognostic (4.23e-2)" "unprognostic (2.36e-1)" "unprognostic (3.79e-1)" "unprognostic (1.07e-1)" "unprognostic (6.29e-2)" "unprognostic (6.91e-6)" "unprognostic (1.13e-5)" "unprognostic (2.32e-1)" "unprognostic (7.60e-2)" "unprognostic (7.98e-2)" "unprognostic (2.16e-1)" 4.9 10.7 8.2 2.8 9.4 2.2 5.3 5.8 10.6 4.2 6.6 7.7 4.4 4.1 7.1 3.3 6.7 3.6 13.0 8.4 8.2 19.4 27.3 3.2 3.9 6.0 7.3 4.2 4.0 7.4 6.4 3.2 6.1 3.7 6.2 8.3 5.2 4.3 10.0 4.2 3.7 3.5 5.9 4.5 3.3 7.1 9.0 4.8 7.3 10.9 2.3 3.2 3.2 7.8 5.4 7.9 11.5 10.3 10.3 10.7 4.1 6.1 8.1 5.3 7.3 3.4 12.1 5.6 4.5 3.3 11.7 2.7 5.1 4.8 5.4 13.5 3.4 5.0 7.6 9.2 3.8 10.4 3.0 6.6 2.1 4.6 4.0 9.8 7.0 9.7 12.8 13.8 9.0 6.3 14.5 11.2 4.3 20.8 9.9 4.9 14.6 6.4 12.7 3.2 6.1 7.6 6.3 8.5 12.5 13.3 5.6 8.3 4.4 12.8 6.7 11.2 5.6 15.4 12.9 10.7 7.7 15.4 5.8 0.0 2.0 0.0 1.5 2.8 1.9 4.0 2.0 2.6 4.4 1.2 1.5 1.7 0.3 1.3 2.5 1.7 2.3 1.8 8.2 9.4 5.8 10.6 8.4 8.2 6.0 7.3 6.1 5.9 9.0 7.8 7.0 16.0 7.8 10.7 2.0 0.9 3.1 9.3 4.6 12.5 4.7 6.9 5.3 4.3 5.4 5.5 0.0 16.4 1.3 4.1 37.2 6.2 36.7 8.9 7.4 5.4 7.2 3.0 8.9 5.6 3.7 5.3 5.6 3.4 1.3 12.8 4.6 21.3 8.7 15.2 9.6 6.0 6.1 4.6 2.0 6.1 6.2 5.0 5.4 4.7 1.5 14.0 0.0 13.6 10.8 4.7 5.2 9.1 3.8 1.2 2.5 46.2 10.4 11.9 0.0 6.3 5.0 28.5 3.7 3.9 1.8 4.0 3.3 20.8 10.1 2.1 NUDT7 ENSG00000140876 "Nudix hydrolase 7" P0C024 16 77722492-77742260 "Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 70.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 58.7;Proximal tubular cells: 42.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 49.7;U-698: 40.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042042 Supported Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus" Nucleoplasm "HPA042042: AB_10806232" "unprognostic (1.92e-1)" "unprognostic (1.17e-2)" "unprognostic (6.64e-2)" "unprognostic (5.95e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.84e-4)" "unprognostic (2.48e-1)" "unprognostic (4.05e-2)" "unprognostic (2.11e-1)" "unprognostic (2.46e-2)" "unprognostic (4.74e-2)" "unprognostic (4.52e-1)" "prognostic favorable (5.36e-11)" "unprognostic (1.19e-1)" "unprognostic (8.96e-2)" "unprognostic (1.32e-1)" "unprognostic (3.42e-2)" 14.4 23.6 5.9 5.2 6.0 2.2 9.2 6.4 7.4 5.8 15.6 12.0 10.8 7.8 17.5 6.6 10.2 6.8 37.6 5.6 7.8 22.1 70.1 6.1 8.9 5.5 5.4 7.3 9.5 16.3 6.0 4.5 6.0 6.6 12.3 9.7 9.0 7.2 8.1 9.0 8.7 7.4 5.3 7.0 7.5 8.7 6.8 6.4 11.8 12.1 9.1 8.2 5.8 6.1 2.1 7.0 6.2 3.5 28.4 7.2 5.8 1.8 9.1 2.7 3.5 2.0 8.8 10.3 6.6 6.9 6.5 6.9 4.7 7.6 1.6 3.3 6.4 0.1 0.4 9.6 3.1 7.1 1.4 12.2 9.4 1.5 5.3 1.2 4.8 14.7 7.6 4.4 1.1 19.1 3.7 16.8 6.6 12.4 1.7 7.8 0.8 3.1 14.1 0.0 5.1 5.0 6.5 2.6 5.7 10.6 18.6 49.7 3.7 3.1 0.4 1.4 0.3 0.0 0.0 40.6 12.1 8.8 0.0 3.8 12.4 1.7 12.6 17.5 14.4 14.2 14.8 15.1 10.2 19.8 19.5 13.5 2.0 3.5 17.5 11.7 31.5 8.8 5.9 6.0 6.4 7.4 5.6 7.8 5.5 5.4 6.0 5.3 6.8 6.1 8.3 16.0 8.7 12.7 4.1 9.7 6.5 14.6 14.2 2.5 10.9 14.5 17.9 18.6 7.9 14.7 0.0 20.3 7.9 12.1 58.7 8.0 11.6 19.5 4.7 8.2 6.7 3.6 4.3 9.5 9.1 8.5 3.6 6.6 1.3 7.0 5.3 41.2 5.9 6.7 5.6 6.6 10.2 9.2 4.4 4.6 5.6 4.1 8.8 1.9 2.1 25.0 10.3 3.5 2.7 4.0 10.4 4.9 1.1 2.0 22.6 42.2 21.0 7.3 6.6 7.1 8.9 14.2 20.0 12.2 13.9 6.7 6.9 10.7 14.8 4.5 OBSCN "ARHGEF30, KIAA1556, KIAA1639, UNC89" ENSG00000154358 "Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF" Q5VST9 1 228208044-228378876 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Calmodulin-binding, Developmental protein, Kinase, Muscle protein, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skeletal muscle: 481.3" "Cell type enriched" "Detected in many" 6 "Cardiomyocytes: 155.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 10.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA021186, HPA065801" Enhanced Approved "Plasma membrane,Cytosol" NA NA 4500000 "Cluster 7: Monocytes - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA021186: AB_1854761, HPA065801: " "unprognostic (8.47e-3)" "unprognostic (1.56e-1)" "unprognostic (9.99e-2)" "prognostic unfavorable (1.64e-4)" "unprognostic (5.30e-3)" "unprognostic (6.36e-2)" "unprognostic (4.54e-3)" "unprognostic (1.82e-1)" "unprognostic (8.81e-2)" "unprognostic (1.93e-2)" "unprognostic (3.38e-1)" "unprognostic (1.45e-1)" "unprognostic (1.57e-3)" "unprognostic (1.34e-1)" "unprognostic (1.77e-1)" "unprognostic (3.53e-1)" "unprognostic (1.16e-2)" 3.5 2.5 2.4 1.4 18.4 1.6 3.7 10.4 4.4 8.1 18.1 5.2 0.7 3.7 1.8 4.6 5.1 1.1 78.5 0.9 2.7 6.6 1.3 8.9 2.1 4.3 2.7 8.6 5.4 1.1 13.6 0.9 2.4 9.9 0.5 0.8 9.4 1.7 481.3 4.7 5.4 0.5 1.0 9.3 5.2 1.9 6.3 4.9 7.5 112.8 1.3 3.2 7.4 0.1 1.7 2.8 3.6 3.7 0.2 0.2 4.6 1.6 0.7 1.7 1.4 2.1 1.3 3.2 5.4 0.7 0.7 2.1 1.3 2.2 0.3 2.0 3.4 1.7 10.5 0.1 1.2 2.4 2.2 1.4 0.6 0.4 0.5 5.1 0.5 7.0 3.2 0.0 0.3 1.8 3.3 3.5 4.9 0.6 2.1 4.4 0.0 1.9 1.8 1.4 1.7 6.3 0.6 3.9 1.0 0.8 3.4 4.0 1.0 0.0 5.1 0.3 0.5 2.5 0.5 4.7 0.0 0.8 2.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.1 2.4 18.4 10.4 4.4 0.9 2.7 4.3 2.7 2.4 1.0 6.3 0.1 1.5 0.0 5.5 1.6 2.4 2.2 6.6 7.7 23.9 4.2 7.3 11.9 155.8 4.3 4.5 5.5 10.4 0.1 1.9 0.7 11.7 3.6 4.9 3.9 3.7 3.1 0.0 3.0 3.9 0.5 0.5 5.7 3.1 11.3 7.0 1.8 1.4 0.5 0.1 0.0 5.3 2.7 4.1 0.3 1.0 4.5 3.1 1.1 1.8 5.6 0.5 7.9 4.1 1.5 1.7 0.8 1.1 4.5 1.5 3.8 0.6 4.1 1.3 3.2 0.0 22.9 6.1 1.0 4.1 9.4 1.7 1.2 5.4 6.2 1.2 3.6 OCIAD2 MGC45416 ENSG00000145247 "OCIA domain containing 2" Q56VL3 4 48885019-48906937 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 155.4" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 1277.4;Proximal enterocytes: 702.0;Proximal tubular cells: 1384.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 325.2;U-251 MG: 399.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040979, HPA041090" Enhanced Enhanced Mitochondria No No "Cluster 20: T-cells - T-cell receptor" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "HPA040979: AB_10795497, HPA041090: AB_10796236" "unprognostic (4.29e-1)" "unprognostic (2.69e-1)" "unprognostic (3.76e-2)" "prognostic favorable (7.37e-4)" "unprognostic (3.49e-2)" "unprognostic (1.66e-2)" "unprognostic (9.05e-2)" "unprognostic (1.23e-1)" "unprognostic (2.00e-1)" "prognostic favorable (6.56e-4)" "prognostic unfavorable (6.89e-4)" "unprognostic (1.38e-1)" "prognostic favorable (2.67e-5)" "unprognostic (1.10e-1)" "unprognostic (8.54e-2)" "unprognostic (8.24e-3)" "prognostic favorable (2.34e-4)" 9.2 20.4 14.1 22.1 13.1 16.3 23.4 10.3 15.3 19.8 14.1 54.7 122.3 20.7 46.9 25.8 22.4 32.4 14.3 17.8 15.6 155.4 129.5 19.0 34.6 13.1 13.2 8.7 26.9 44.4 33.6 8.6 11.7 23.8 49.9 26.9 40.2 29.2 4.4 20.0 88.4 15.0 11.6 12.6 85.0 6.3 13.7 53.6 37.4 3.9 40.3 28.1 12.0 12.7 208.9 108.5 1.6 0.0 0.0 0.0 2.7 53.3 23.9 28.4 26.9 0.0 249.4 35.7 230.1 30.5 248.0 65.5 29.7 325.2 29.1 83.8 22.6 0.1 78.6 0.1 25.6 101.7 0.3 14.7 150.8 0.1 61.1 81.4 115.5 140.2 0.1 17.6 30.3 78.3 172.2 70.2 102.5 234.2 145.2 38.5 0.1 59.4 288.7 135.0 230.3 69.5 75.4 25.5 5.4 0.8 26.2 25.2 195.6 0.2 215.1 1.2 399.5 49.5 59.6 113.3 163.0 0.3 0.4 208.4 3.5 69.1 101.6 1.5 136.9 168.0 191.0 147.3 18.1 156.7 247.2 165.0 11.2 156.0 1.3 122.4 338.7 137.7 14.1 13.1 10.3 15.3 17.8 15.6 13.1 13.2 11.7 11.6 13.7 12.7 135.9 28.9 70.6 2.0 102.5 109.0 146.6 401.4 81.4 17.6 152.7 190.6 39.2 194.5 224.2 176.6 29.2 46.2 66.3 359.7 217.2 510.5 1.4 197.5 22.9 103.3 306.4 38.9 10.1 570.2 11.4 14.9 157.5 190.8 36.8 75.3 31.1 193.9 44.3 1.7 11.6 301.3 341.8 6.4 27.0 2.5 5.0 21.7 65.8 5.6 15.9 49.9 82.4 2.5 1.8 1277.4 311.6 21.4 53.5 180.1 702.0 1384.9 171.4 77.6 0.0 3.7 41.8 2.6 3.2 105.2 131.4 15.3 129.8 52.1 188.6 239.2 OCLN PPP1R115 ENSG00000197822 Occludin Q16625 5 69492292-69558104 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 31.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 109.0;Glandular and luminal cells: 119.7;Urothelial cells: 224.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.7" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.7" "Cell line enhanced" "Detected in many" "A-431: 23.3;CAPAN-2: 39.8;HaCaT: 33.4;RPTEC TERT1: 25.7;SK-BR-3: 27.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005933, CAB013075, CAB068212, CAB068213, CAB068214" Enhanced Supported "Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" "CAB013075: AB_2533101, CAB068212: AB_2665711, CAB068213: AB_2665712, CAB068214: AB_2665713, HPA005933: AB_1079520" "unprognostic (2.28e-1)" "unprognostic (1.88e-1)" "unprognostic (2.50e-2)" "unprognostic (9.94e-2)" "unprognostic (3.65e-1)" "unprognostic (1.39e-1)" "unprognostic (2.24e-1)" "unprognostic (1.08e-2)" "unprognostic (8.25e-2)" "unprognostic (8.20e-2)" "unprognostic (2.58e-2)" "unprognostic (3.48e-1)" "prognostic favorable (6.59e-11)" "unprognostic (2.83e-1)" "unprognostic (4.01e-1)" "unprognostic (1.33e-1)" "unprognostic (3.35e-1)" 1.2 0.7 6.2 1.6 6.5 1.8 7.8 7.2 6.7 6.8 22.2 11.0 10.3 2.1 4.0 11.6 7.5 8.5 1.5 5.9 5.4 11.0 18.8 15.1 0.6 9.3 7.7 2.3 20.2 8.3 3.4 3.9 8.3 3.5 11.2 2.3 6.7 4.6 0.6 11.3 10.0 0.6 5.4 2.1 15.2 2.4 6.5 0.9 31.4 0.6 2.8 5.0 7.9 7.4 23.3 4.5 0.6 0.9 0.6 0.9 15.1 0.3 1.6 2.5 3.3 20.7 39.8 0.5 5.9 1.1 8.3 33.4 7.2 4.3 7.8 0.3 12.2 2.4 1.1 9.8 0.3 1.2 2.5 0.1 6.4 4.1 1.0 1.6 1.4 3.1 0.1 0.4 0.1 22.4 1.5 1.2 3.1 8.0 2.1 0.2 6.0 1.1 25.7 22.2 2.7 2.8 0.3 27.2 0.9 5.0 14.7 4.0 1.2 0.4 7.7 1.8 2.7 0.5 0.4 0.3 0.3 0.3 0.6 1.0 0.2 0.5 0.2 0.1 0.2 0.3 0.2 0.1 0.1 0.4 0.2 0.2 2.7 0.5 0.1 0.4 0.1 0.1 6.2 6.5 7.2 6.7 5.9 5.4 9.3 7.7 8.3 5.4 6.5 7.4 4.8 109.0 67.3 1.6 3.2 3.7 60.8 7.6 1.8 5.7 49.7 16.9 1.4 64.3 51.0 25.8 14.6 30.3 3.6 94.1 9.8 65.6 1.9 78.5 12.1 10.7 26.3 2.5 1.3 61.6 2.5 5.8 46.4 119.7 2.5 6.5 18.2 48.3 3.0 6.7 1.1 45.1 16.2 12.9 1.2 1.6 3.1 2.4 1.8 16.9 3.9 2.8 1.0 0.5 1.5 64.6 61.8 1.5 1.1 101.5 42.3 10.5 63.0 6.3 13.1 3.3 4.4 4.7 8.2 29.5 15.5 16.4 4.3 0.7 47.9 224.0 ODF2L KIAA1229 ENSG00000122417 "Outer dense fiber of sperm tails 2 like" Q9ULJ1 1 86346824-86396342 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 335.7;Respiratory ciliated cells: 361.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028020, HPA028095, HPA028333" Uncertain NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" "HPA028020: AB_10601670, HPA028095: AB_10611385, HPA028333: AB_10601007" "unprognostic (4.81e-2)" "unprognostic (3.11e-1)" "unprognostic (1.03e-1)" "unprognostic (4.72e-2)" "unprognostic (2.92e-2)" "unprognostic (3.80e-3)" "unprognostic (5.61e-3)" "unprognostic (2.25e-1)" "unprognostic (2.08e-3)" "unprognostic (1.07e-1)" "unprognostic (6.27e-2)" "unprognostic (5.25e-2)" "prognostic unfavorable (4.69e-7)" "unprognostic (2.40e-1)" "unprognostic (5.86e-2)" "unprognostic (2.40e-1)" "unprognostic (5.04e-3)" 22.6 20.2 14.0 14.0 15.8 17.1 23.0 16.8 20.0 21.7 14.3 18.4 8.3 18.1 23.3 17.6 23.7 15.2 13.4 14.2 12.7 24.5 7.1 22.9 16.6 13.2 14.8 18.8 11.4 7.2 28.1 10.1 8.1 20.0 14.8 41.2 15.5 10.5 5.2 11.9 22.8 9.7 9.0 36.5 8.7 13.3 15.2 21.9 22.1 3.7 13.2 15.3 17.6 16.8 30.0 7.9 19.7 15.1 21.0 35.8 20.6 28.6 17.4 27.6 32.0 6.2 16.3 0.7 26.3 15.3 35.2 15.3 8.1 16.7 23.6 14.1 12.8 7.3 24.5 0.6 15.9 13.1 9.3 16.5 20.2 41.7 11.4 19.9 45.3 19.8 10.2 6.8 16.4 4.0 15.7 13.8 24.1 6.5 14.5 21.0 14.8 3.2 27.7 40.0 19.5 14.1 25.8 26.2 54.9 30.7 8.5 12.6 41.7 23.0 21.4 31.8 29.4 1.9 1.0 12.3 5.4 6.7 26.5 5.6 2.2 13.6 26.1 3.4 51.5 20.9 30.2 21.0 2.4 21.2 19.3 18.8 6.3 14.8 4.1 12.7 31.8 4.9 14.0 15.8 16.8 20.0 14.2 12.7 13.2 14.8 8.1 9.0 15.2 16.8 72.9 93.0 76.2 22.5 54.0 25.0 54.6 49.0 15.4 139.3 67.0 49.3 12.0 21.5 133.2 80.9 141.8 7.3 73.9 23.1 23.5 61.9 48.5 335.7 57.3 78.7 41.3 16.6 119.1 27.1 35.1 52.5 13.3 70.6 36.7 55.9 72.8 3.9 15.5 57.2 107.2 68.5 42.7 21.2 19.7 10.3 24.8 18.6 56.9 38.4 21.8 28.8 80.3 29.1 49.9 55.9 28.1 28.6 38.9 16.5 9.3 23.1 361.9 120.3 19.7 24.3 32.1 64.0 27.4 19.2 17.3 2.9 106.4 60.6 28.2 67.3 OGN "mimecan, OIF, SLRR3A" ENSG00000106809 Osteoglycin P20774 9 92383268-92404696 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.0" "Group enriched" "Detected in many" 8 "Endometrial stromal cells: 104.1;Fibroblasts: 326.2;Leydig cells: 166.2;Peritubular cells: 212.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "T-reg: 1.7" "Lineage enriched" "Detected in single" 9 "T-cells: 1.7" "Group enriched" "Detected in some" 4 "ASC TERT1: 22.2;HSkMC: 9.7;JURKAT: 15.7;MOLT-4: 32.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013132 Approved Supported "Endoplasmic reticulum" "Secreted in other tissues" NA NA 170000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA013132: AB_1854825" "unprognostic (2.31e-1)" "unprognostic (3.94e-3)" "unprognostic (1.74e-1)" "unprognostic (2.08e-2)" "unprognostic (2.60e-1)" "unprognostic (2.70e-1)" "unprognostic (1.44e-4)" "unprognostic (4.42e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (4.04e-4)" "unprognostic (2.47e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.92e-4)" "unprognostic (3.37e-3)" "unprognostic (3.86e-2)" "unprognostic (2.20e-3)" "prognostic unfavorable (2.03e-4)" 100.1 22.5 1.4 6.0 3.0 0.2 53.8 4.7 6.8 216.0 11.0 43.0 10.6 130.5 44.9 30.8 67.1 164.7 79.8 1.7 2.3 6.4 4.1 18.6 2.1 1.8 1.8 91.8 11.1 117.3 19.1 22.7 2.0 57.9 32.2 0.0 3.2 19.3 2.6 3.8 23.6 118.0 2.3 2.4 22.0 13.3 2.2 4.5 14.7 22.0 5.6 54.0 23.3 2.1 0.0 0.0 0.0 0.0 4.4 22.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 9.7 0.0 0.0 0.0 0.0 0.0 15.7 0.0 0.0 0.0 0.1 32.2 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 1.4 3.0 4.7 6.8 1.7 2.3 1.8 1.8 2.0 2.3 2.2 2.1 10.3 6.4 1.5 1.0 0.4 4.2 0.1 0.0 1.2 0.6 0.7 0.4 2.6 10.0 7.4 3.7 0.0 2.0 0.6 0.1 0.0 0.0 1.2 2.9 104.1 5.2 0.0 0.0 1.9 0.0 1.7 326.2 7.7 1.7 1.3 0.0 20.0 0.1 4.6 0.0 1.8 0.0 0.0 0.3 11.1 4.2 166.2 2.3 1.8 16.9 0.2 0.1 0.0 2.0 1.6 0.0 0.0 212.1 0.7 0.4 0.0 0.0 2.9 0.2 6.6 4.7 22.7 0.6 0.6 0.7 4.5 5.7 2.1 1.6 0.0 0.2 OLFML2A FLJ00237 ENSG00000185585 "Olfactomedin like 2A" Q68BL7 9 124777133-124814885 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 40.1;Endothelial cells: 21.2;Fibroblasts: 29.0;Skeletal myocytes: 63.0;Smooth muscle cells: 36.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 160.0;GAMG: 34.0;HeLa: 39.8;hTERT-RPE1: 38.0;WM-115: 64.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021180, HPA022254" Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" NA NA 240000 "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA021180: AB_1854790, HPA022254: AB_1854791" "unprognostic (1.12e-1)" "unprognostic (3.07e-2)" "unprognostic (3.16e-1)" "unprognostic (2.45e-1)" "unprognostic (4.01e-2)" "unprognostic (1.27e-1)" "unprognostic (1.15e-1)" "unprognostic (3.00e-1)" "unprognostic (1.26e-3)" "unprognostic (7.53e-2)" "unprognostic (2.49e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (3.73e-5)" "unprognostic (5.72e-3)" "unprognostic (3.30e-2)" "unprognostic (7.91e-2)" "unprognostic (1.05e-2)" 15.4 2.9 2.6 2.7 3.1 0.3 11.1 2.2 4.6 25.0 3.3 29.9 3.3 25.3 2.8 8.2 6.4 4.8 16.4 2.2 2.4 4.3 0.7 10.5 2.4 2.8 2.1 12.0 4.8 4.6 2.8 7.0 2.8 7.4 6.2 2.2 7.0 12.2 10.8 16.0 6.9 16.0 2.1 32.8 5.5 1.1 2.6 3.1 19.1 10.0 3.7 17.6 14.6 2.1 0.8 14.6 1.2 0.4 16.8 160.0 0.1 1.8 8.2 3.5 3.5 0.2 2.2 0.0 3.4 0.1 34.0 25.5 0.4 0.8 4.0 0.0 0.1 0.0 39.8 0.1 0.9 0.0 0.1 11.3 2.7 10.2 1.4 38.0 0.0 0.0 0.0 0.2 1.8 0.4 0.0 0.3 3.4 0.0 0.9 0.0 9.5 0.0 0.0 1.2 0.0 0.1 2.9 0.2 4.3 28.6 3.9 0.5 0.1 5.2 4.6 5.5 0.7 1.9 0.0 0.1 15.2 0.8 64.1 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.1 2.6 3.1 2.2 4.6 2.2 2.4 2.8 2.1 2.8 2.1 2.6 2.1 40.1 0.0 1.3 0.7 0.4 12.0 5.9 17.5 6.2 0.6 2.9 8.3 13.8 1.5 5.5 0.0 2.1 0.3 0.5 0.0 0.0 0.1 0.7 0.2 1.5 21.2 0.0 0.0 0.4 0.6 0.3 29.0 0.5 0.2 0.0 0.9 3.6 0.1 0.1 0.0 0.6 0.0 4.1 1.5 7.9 1.4 2.8 0.9 10.6 8.4 0.1 0.3 0.0 0.0 0.1 0.0 0.0 1.5 0.1 4.0 0.0 0.1 11.5 4.0 13.1 63.0 36.4 0.4 0.7 4.5 8.4 0.0 0.6 4.2 0.0 3.5 ORM1 ENSG00000229314 "Orosomucoid 1" P02763 9 114323056-114326475 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Acute phase, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 193 "liver: 42973.6" "Cell type enriched" "Detected in some" 46 "Hepatocytes: 58657.7" "Cancer enriched" "Detected in many" 16 "liver cancer: 2506.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 47 "neutrophil: 193.9" "Lineage enriched" "Detected in many" 47 "granulocytes: 193.9" "Cell line enriched" "Detected in some" 12 "Hep G2: 1182.7" "CAB006265, HPA046438, HPA047725, HPA057726" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 945000000000 61000000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "Golgi apparatus" "CAB006265: AB_425575, HPA046438: AB_2679666, HPA047725: AB_2680133, HPA057726: AB_2683512" "unprognostic (3.85e-1)" "unprognostic (2.12e-1)" "unprognostic (1.09e-2)" "unprognostic (2.16e-2)" "unprognostic (3.22e-2)" "unprognostic (1.47e-1)" "unprognostic (2.29e-1)" "unprognostic (2.26e-1)" "unprognostic (1.16e-1)" "unprognostic (4.85e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (2.35e-4)" "unprognostic (2.10e-1)" "unprognostic (4.38e-2)" "unprognostic (9.32e-3)" "unprognostic (4.51e-2)" 13.4 10.3 0.1 12.7 0.3 223.1 6.6 0.0 0.4 2.7 0.2 1.5 0.1 2.7 0.3 1.9 1.9 1.0 3.4 0.2 0.2 4.9 42973.6 24.4 0.7 0.4 0.2 1.6 8.1 0.0 1.4 1.3 0.1 57.6 0.0 1.1 1.4 0.0 2.0 1.7 2.3 0.3 0.2 51.3 19.2 2.7 0.1 1.2 2.8 0.3 0.1 1.6 2.2 0.2 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 2.1 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 3.4 0.6 1182.7 0.1 5.3 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.5 0.0 0.2 0.0 0.2 1.0 0.1 0.0 0.7 7.1 0.0 0.0 0.4 0.0 0.0 5.7 5.5 0.0 0.0 0.4 102.0 1.2 0.0 0.5 0.0 0.0 1.2 0.6 3.5 0.0 4.3 0.1 0.0 4.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 193.9 0.0 1.0 0.0 0.0 1.8 0.1 0.3 0.0 0.4 0.2 0.2 0.4 0.2 0.1 0.2 0.1 0.2 0.0 3.2 18.1 0.0 81.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1166.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 23.6 0.0 1.3 0.2 34.4 0.0 890.4 0.0 4.9 0.3 0.2 0.0 2.5 0.0 0.0 930.9 58657.7 0.1 0.0 0.0 0.0 0.0 1260.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.0 29.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 78.6 0.0 0.0 0.3 ORM2 "AGP-B, AGP-B', AGP2" ENSG00000228278 "Orosomucoid 2" P19652 9 114329869-114333251 "Plasma proteins, Predicted secreted proteins" "Acute phase, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 327 "liver: 8873.2" "Cell type enriched" "Detected in some" 41 "Hepatocytes: 10792.5" "Cancer enriched" "Detected in many" 34 "liver cancer: 873.1" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 40 "neutrophil: 12.0" "Lineage enriched" "Detected in single" 40 "granulocytes: 12.0" "Cell line enriched" "Detected in some" 232 "Hep G2: 831.1" "HPA046438, HPA047725, HPA057726" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 422000000 41000000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Golgi apparatus" "HPA046438: AB_2679666, HPA047725: AB_2680133, HPA057726: AB_2683512" "unprognostic (6.77e-2)" "unprognostic (8.00e-2)" "unprognostic (1.19e-1)" "unprognostic (4.44e-3)" "unprognostic (1.18e-1)" "unprognostic (5.61e-2)" "unprognostic (5.66e-2)" "unprognostic (9.70e-2)" "unprognostic (3.05e-1)" "unprognostic (1.48e-1)" "unprognostic (1.99e-2)" "unprognostic (5.76e-2)" "prognostic unfavorable (1.23e-9)" "unprognostic (3.23e-1)" "unprognostic (6.80e-2)" "unprognostic (7.62e-2)" "unprognostic (9.15e-4)" 4.0 4.0 0.2 3.2 0.4 27.1 3.0 0.0 0.2 1.3 0.2 0.3 0.2 2.1 0.1 0.4 0.4 0.6 0.8 0.1 0.1 1.7 8873.2 5.8 1.1 0.2 0.3 0.3 2.1 0.0 0.2 0.2 0.1 23.6 0.1 3.6 0.3 0.0 0.4 0.4 0.4 0.1 0.2 7.3 21.9 1.4 0.1 0.5 0.3 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.2 0.0 831.1 0.0 3.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.2 0.0 0.0 0.1 1.1 0.4 2.5 0.0 0.3 1.9 0.1 0.0 0.3 0.1 0.0 2.6 2.0 0.2 0.1 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.7 0.6 2.2 0.0 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.1 0.0 0.0 0.1 0.2 0.4 0.0 0.2 0.1 0.1 0.2 0.3 0.1 0.2 0.1 0.2 0.0 0.0 10.5 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 263.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 6.6 1.1 0.1 7.0 0.0 141.7 0.0 6.0 0.0 0.0 15.8 1.3 0.0 0.0 162.8 10792.5 0.0 0.0 0.0 0.0 0.0 236.1 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.2 P2RX6 "MGC129625, P2RXL1, P2X6, P2XM" ENSG00000099957 "Purinergic receptor P2X 6" O15547 22 21009808-21028830 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 3.4;skeletal muscle: 12.4;tongue: 7.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.6;Excitatory neurons: 8.9;Inhibitory neurons: 7.9;Ionocytes: 8.2;Skeletal myocytes: 20.8" "Group enriched" "Detected in some" 5 "glioma: 1.0;melanoma: 2.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 9.7;LHCN-M2: 6.7;RH-30: 4.2;U-87 MG: 11.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028776, HPA028777" Approved Approved Nucleoli,Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Nucleoli, Cytosol" "HPA028776: AB_2672771, HPA028777: AB_2672772" "unprognostic (1.81e-2)" "unprognostic (5.15e-3)" "unprognostic (2.11e-2)" "unprognostic (1.12e-1)" "unprognostic (4.28e-2)" "unprognostic (1.79e-5)" "unprognostic (1.70e-2)" "unprognostic (6.20e-2)" "unprognostic (1.49e-1)" "unprognostic (2.59e-2)" "unprognostic (1.89e-2)" "unprognostic (2.45e-2)" "unprognostic (2.88e-10)" "unprognostic (2.81e-1)" "unprognostic (1.38e-1)" "unprognostic (7.33e-2)" "unprognostic (2.39e-3)" 0.3 1.1 0.0 0.3 0.2 0.0 0.1 1.0 2.6 0.1 0.4 0.1 0.0 0.2 0.0 0.2 0.3 0.8 1.3 1.0 1.5 0.2 0.1 0.3 0.2 3.4 0.4 0.3 0.1 0.0 1.3 0.8 3.4 0.3 0.0 0.3 0.2 0.7 12.4 0.1 0.1 0.1 0.1 1.6 0.2 1.1 0.6 0.0 0.0 7.7 0.0 0.2 0.1 1.2 0.0 0.4 0.7 0.2 0.1 0.0 0.8 0.1 1.7 0.7 1.2 0.0 0.0 0.0 1.1 0.4 2.9 1.3 0.0 0.1 0.1 0.2 0.0 1.9 0.9 0.0 2.8 0.0 2.4 0.3 0.0 1.2 0.0 9.7 0.0 0.0 2.1 0.6 6.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 4.2 0.2 0.0 0.0 0.2 3.1 1.2 0.1 0.5 0.1 0.0 0.0 0.0 2.1 0.3 0.0 0.0 0.2 0.0 0.0 11.7 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 2.6 1.0 1.5 3.4 0.4 3.4 0.1 0.6 1.2 0.2 0.0 0.6 0.3 0.1 0.1 0.8 0.8 0.6 7.6 0.0 0.4 2.4 0.0 0.2 1.8 0.0 0.5 0.0 0.1 0.0 0.0 2.2 1.8 0.5 0.2 3.5 2.7 8.9 0.0 0.4 1.4 0.0 0.7 2.5 0.1 1.8 0.1 0.1 1.7 7.9 0.7 8.2 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 1.1 0.0 5.0 3.3 0.0 0.0 0.4 0.1 0.2 0.0 0.3 3.2 1.1 0.0 20.8 0.4 1.6 0.4 0.3 0.1 0.4 0.5 0.1 0.1 0.2 P2RY13 "FKSG77, GPR86, GPR94, P2Y13" ENSG00000181631 "Purinergic receptor P2Y13" Q9BPV8 3 151326312-151329549 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.1;lymphoid tissue: 36.9" "Group enriched" "Detected in some" 9 "Kupffer cells: 124.4;Macrophages: 53.2;Microglial cells: 66.5;monocytes: 63.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 581.5" "Group enriched" "Detected in many" 6 "granulocytes: 581.5;monocytes: 185.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049047 Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA049047: AB_2680611" "unprognostic (1.09e-3)" "unprognostic (7.51e-4)" "unprognostic (1.68e-2)" "unprognostic (2.37e-3)" "unprognostic (3.95e-2)" "unprognostic (8.66e-3)" "unprognostic (7.66e-2)" "unprognostic (5.48e-3)" "unprognostic (2.84e-3)" "unprognostic (1.83e-1)" "unprognostic (4.97e-2)" "unprognostic (1.17e-1)" "unprognostic (4.05e-1)" "unprognostic (4.46e-1)" "unprognostic (5.95e-2)" "unprognostic (2.21e-3)" "unprognostic (3.78e-1)" 4.8 3.8 1.6 20.6 1.6 25.1 4.2 1.6 2.2 2.6 2.7 4.5 4.6 1.9 0.8 3.2 3.1 3.9 1.4 1.9 2.0 1.6 8.2 7.6 18.2 3.1 2.4 1.6 1.2 1.6 0.5 3.3 2.8 1.4 6.2 0.1 2.9 3.2 0.7 2.1 11.0 5.3 3.7 36.9 3.1 0.7 4.2 4.5 1.3 3.8 8.4 4.1 0.3 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 152.5 137.2 0.3 155.4 0.3 1.5 0.2 0.2 66.4 0.6 0.2 0.3 581.5 0.1 185.6 1.1 0.2 77.6 1.6 1.6 1.6 2.2 1.9 2.0 3.1 2.4 2.8 3.7 4.2 4.0 0.9 0.0 6.1 0.0 1.3 0.0 0.1 0.0 0.0 0.8 0.6 0.6 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 3.6 0.3 0.0 0.2 0.6 0.5 0.0 2.5 0.0 0.7 0.4 7.7 1.7 0.2 0.0 0.0 124.4 4.5 0.0 0.0 53.2 0.0 66.5 63.3 1.1 2.1 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.2 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.1 0.9 0.0 0.0 0.0 PABPC5 PABP5 ENSG00000174740 "Poly(A) binding protein cytoplasmic 5" Q96DU9 X 91434595-91438584 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 7.4;ovary: 11.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 12.8;Endometrial stromal cells: 8.3;Horizontal cells: 8.4;Oligodendrocyte precursor cells: 7.5;Peritubular cells: 11.7;Sertoli cells: 13.1;Skeletal myocytes: 11.2;Theca cells: 12.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.0;HSkMC: 2.8;LHCN-M2: 1.9;RH-30: 8.4;U-2 OS: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA000164, HPA000165" Approved NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "HPA000164: AB_1079551, HPA000165: AB_1079552" "unprognostic (1.05e-1)" "unprognostic (2.98e-1)" "unprognostic (3.68e-2)" "unprognostic (2.92e-1)" "unprognostic (1.37e-1)" "unprognostic (1.56e-2)" "unprognostic (1.23e-1)" "unprognostic (3.52e-1)" "unprognostic (2.89e-2)" "unprognostic (1.01e-1)" "unprognostic (2.93e-2)" "unprognostic (2.46e-1)" "unprognostic (1.26e-1)" "unprognostic (6.87e-3)" "unprognostic (1.27e-1)" "unprognostic (4.55e-2)" "unprognostic (8.07e-2)" 2.1 7.4 1.1 0.7 1.3 0.0 0.9 1.1 1.5 2.3 0.5 1.5 0.4 3.1 2.5 1.2 1.8 1.3 1.6 1.0 1.4 0.8 0.3 0.9 0.8 1.5 1.3 11.1 0.4 1.2 1.3 0.7 1.4 2.3 0.7 1.2 0.8 2.0 0.5 0.4 0.7 2.9 1.4 1.8 0.7 1.6 1.4 0.2 2.0 0.9 0.5 1.3 1.0 1.7 0.0 0.0 7.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.9 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.3 1.1 1.5 1.0 1.4 1.5 1.3 1.4 1.4 1.4 1.7 1.3 0.0 0.0 0.3 0.0 0.1 0.3 0.0 0.0 12.8 0.1 1.1 0.7 0.0 0.0 1.8 2.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 8.3 1.3 0.0 0.0 1.7 0.0 0.0 5.0 0.0 0.1 0.0 6.6 1.1 0.0 0.1 8.4 1.8 0.0 0.0 0.0 0.4 0.7 5.9 0.1 3.6 1.0 0.0 4.1 0.0 7.5 3.6 0.0 0.0 11.7 0.0 0.3 0.0 0.1 0.0 3.4 13.1 11.2 4.4 0.2 0.3 0.1 0.3 0.0 0.1 12.0 0.0 0.0 PAFAH2 HSD-PLA2 ENSG00000158006 "Platelet activating factor acetylhydrolase 2" Q99487 1 25959767-25998117 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 48.7" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 52.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018157 Approved NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA018157: AB_1854928" "unprognostic (9.89e-2)" "unprognostic (2.60e-1)" "unprognostic (3.63e-3)" "prognostic favorable (3.28e-6)" "unprognostic (5.19e-2)" "unprognostic (2.12e-1)" "unprognostic (1.05e-1)" "unprognostic (1.78e-1)" "unprognostic (2.43e-1)" "unprognostic (1.04e-1)" "unprognostic (4.46e-2)" "unprognostic (2.62e-1)" "prognostic favorable (0.00e+0)" "unprognostic (8.15e-2)" "unprognostic (8.17e-2)" "unprognostic (1.59e-2)" "unprognostic (7.27e-2)" 4.6 7.3 4.7 6.5 6.5 6.8 9.2 6.3 6.0 8.8 6.7 16.3 17.4 4.9 9.9 7.8 8.3 10.4 9.7 4.5 5.8 19.3 18.3 8.6 8.4 6.4 6.5 4.7 31.2 22.9 5.9 9.2 6.5 8.8 16.6 14.1 10.0 6.3 18.0 11.4 19.0 6.9 5.5 7.6 15.6 7.7 6.5 48.7 16.4 10.7 7.4 7.0 5.5 8.2 8.6 10.7 6.7 7.6 13.9 10.9 13.7 9.6 5.0 8.6 5.7 4.4 18.1 3.8 11.7 5.7 8.1 7.5 10.1 9.3 11.0 7.8 6.1 6.3 4.6 8.8 8.4 3.3 52.5 7.2 21.2 13.2 8.7 4.7 8.3 8.9 8.9 7.1 11.7 3.8 10.3 3.3 13.4 29.9 5.9 8.4 6.3 8.7 13.9 3.0 8.0 6.8 5.7 7.7 18.2 11.0 12.7 6.0 7.8 5.9 7.4 12.5 7.7 13.0 18.1 4.8 12.5 13.2 20.0 36.2 6.7 60.2 23.7 6.4 15.3 3.5 8.3 15.4 5.0 4.4 10.6 14.9 5.8 17.4 2.4 39.0 9.0 8.7 4.7 6.5 6.3 6.0 4.5 5.8 6.4 6.5 6.5 5.5 6.5 8.2 4.6 16.0 12.8 9.8 3.2 1.5 2.1 5.3 1.8 9.5 9.4 4.8 6.8 11.5 11.9 18.4 27.1 11.2 37.7 34.9 3.9 11.1 1.1 8.6 4.5 5.6 7.8 3.2 4.0 7.3 9.5 3.5 12.2 13.2 27.8 7.3 5.7 21.4 11.2 5.0 3.6 18.2 4.1 11.6 1.6 1.0 2.5 7.1 8.8 5.6 7.3 6.3 23.7 4.0 10.0 10.6 15.8 2.6 6.5 4.2 43.1 18.3 8.9 8.8 6.6 5.3 4.1 19.9 8.9 4.5 3.8 10.0 9.0 4.4 19.4 4.9 PAICS "ADE2H1, AIRC, PAIS" ENSG00000128050 "Phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase" P22234 4 56435741-56464578 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Decarboxylase, Ligase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 157.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035895, HPA041538" Approved Approved Cytosol Yes No 490000 "Cluster 30: Non-specific - Translation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA035895: AB_10669660, HPA041538: AB_2677540" "unprognostic (2.59e-3)" "unprognostic (7.90e-3)" "unprognostic (3.84e-3)" "unprognostic (2.88e-2)" "unprognostic (9.85e-2)" "unprognostic (2.82e-3)" "prognostic unfavorable (1.50e-4)" "unprognostic (8.07e-3)" "unprognostic (1.23e-2)" "prognostic favorable (8.44e-4)" "unprognostic (1.48e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (5.85e-5)" "unprognostic (7.11e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (2.41e-4)" "unprognostic (2.16e-1)" 24.5 40.2 22.7 40.1 26.7 46.8 54.6 28.3 25.0 29.3 21.6 42.8 32.1 29.7 22.1 36.3 35.4 17.8 19.7 20.3 27.8 42.7 109.7 14.1 51.3 26.0 30.1 30.7 21.7 39.5 17.7 45.9 26.1 31.0 54.7 30.4 26.4 25.8 32.4 37.6 30.8 35.7 25.6 18.3 20.7 29.5 26.8 56.4 32.4 24.1 64.5 37.4 25.4 27.2 239.3 175.3 354.3 220.6 74.3 166.1 304.0 201.7 145.1 282.5 276.0 280.5 275.7 548.0 228.3 136.0 154.1 143.6 565.5 293.0 480.8 110.4 198.8 298.7 259.5 313.4 141.8 537.1 127.6 141.9 207.9 301.0 225.0 155.7 235.4 308.6 524.7 198.5 246.8 159.3 621.5 267.2 407.5 454.8 216.5 496.2 151.7 361.5 268.4 164.5 378.8 226.4 198.6 273.7 124.3 287.2 181.2 169.8 127.7 222.6 290.1 221.8 419.0 139.1 128.2 571.1 234.8 385.2 251.0 6.0 5.2 0.4 5.2 8.7 15.0 17.8 14.4 9.2 15.3 11.0 17.4 15.5 1.1 15.9 6.9 17.0 11.2 8.7 22.7 26.7 28.3 25.0 20.3 27.8 26.0 30.1 26.1 25.6 26.8 27.2 16.4 22.4 22.9 17.0 35.7 56.6 71.9 66.0 54.1 27.4 35.8 37.5 23.3 50.1 32.3 33.1 6.2 134.4 15.3 20.5 37.2 45.0 69.4 15.2 49.1 25.1 24.7 80.8 9.1 26.3 157.5 34.2 15.3 23.3 21.0 69.1 13.2 78.7 51.5 28.6 14.6 41.0 34.6 16.1 17.2 10.6 29.8 16.1 17.8 6.5 20.2 14.0 6.2 13.0 12.2 27.4 18.6 23.3 48.1 81.7 15.9 47.7 17.9 24.6 0.0 31.3 29.2 40.0 50.3 53.1 50.4 54.6 16.8 66.4 69.7 48.9 PALD1 "KIAA1274, PALD" ENSG00000107719 "Phosphatase domain containing paladin 1" Q9ULE6 10 70478767-70568450 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Microglial cells: 129.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "plasmacytoid DC: 5.0" "Lineage enriched" "Detected in single" 27 "dendritic cells: 5.0" "Cell line enhanced" "Detected in many" "AN3-CA: 21.5;Daudi: 26.7;NB-4: 25.7;RPMI-8226: 32.8;U-698: 26.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015696, HPA017343" Uncertain NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA015696: AB_1852399, HPA017343: AB_1852397" "unprognostic (1.11e-1)" "unprognostic (1.68e-1)" "unprognostic (2.64e-1)" "unprognostic (1.51e-1)" "unprognostic (7.94e-2)" "unprognostic (2.52e-3)" "unprognostic (4.52e-3)" "unprognostic (3.55e-2)" "unprognostic (4.96e-2)" "unprognostic (3.34e-2)" "unprognostic (6.56e-2)" "unprognostic (2.48e-1)" "unprognostic (8.20e-3)" "unprognostic (2.73e-2)" "unprognostic (9.27e-2)" "unprognostic (2.46e-1)" "unprognostic (8.81e-3)" 6.9 4.5 16.3 5.1 15.0 2.5 5.3 16.1 18.1 5.5 10.6 14.3 2.7 4.8 1.2 4.7 5.8 4.6 7.4 15.4 16.4 5.3 1.6 19.9 9.2 23.6 17.5 5.5 7.2 1.6 5.4 7.6 20.7 6.0 2.2 1.0 4.0 2.1 5.6 5.5 8.1 4.8 22.1 14.7 7.5 3.6 21.4 4.6 8.2 3.0 8.0 5.2 3.7 19.9 0.0 6.4 7.2 21.5 0.0 0.0 0.0 0.0 0.0 1.8 0.4 2.7 0.2 26.7 5.5 0.0 0.3 0.1 11.9 0.0 0.5 0.1 13.6 0.0 0.9 0.5 2.2 9.0 0.0 0.0 0.0 0.7 0.0 1.9 3.1 8.2 1.4 3.6 0.2 2.2 4.6 25.7 7.6 0.0 0.0 13.5 0.1 32.8 1.9 0.0 7.1 5.3 0.3 0.1 0.6 0.9 0.0 1.9 0.6 0.0 9.7 0.0 0.8 0.3 0.0 26.3 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 5.0 0.0 0.0 16.3 15.0 16.1 18.1 15.4 16.4 23.6 17.5 20.7 22.1 21.4 19.9 15.0 0.0 1.1 4.6 3.2 1.3 0.1 0.1 4.0 0.5 1.3 2.2 3.6 1.5 0.0 1.8 0.0 0.0 11.4 0.0 0.0 1.7 0.9 1.1 0.6 20.3 0.0 0.0 4.9 0.2 0.1 3.5 0.0 1.8 1.3 0.7 12.5 0.2 7.4 0.0 2.2 0.0 0.0 10.8 3.3 0.5 1.8 12.2 1.8 129.3 0.3 3.0 0.0 6.6 0.9 0.1 0.0 0.7 5.1 0.3 0.0 0.1 0.0 0.4 0.0 3.0 5.1 0.2 2.7 0.5 1.3 0.0 0.6 1.2 0.0 0.0 PAPLN MGC50452 ENSG00000100767 "Papilin, proteoglycan like sulfated glycoprotein" O95428 14 73237497-73274640 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 119.8;Endometrial stromal cells: 37.9;Leydig cells: 34.5;Peritubular cells: 44.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "neutrophil: 2.5;plasmacytoid DC: 5.4" "Group enriched" "Detected in many" 7 "dendritic cells: 5.4;granulocytes: 2.5" "Cell line enhanced" "Detected in many" "HHSteC: 16.1;HSkMC: 30.6;hTCEpi: 11.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA048682, HPA053453" Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA 76000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA048682: AB_2680492, HPA053453: AB_2682155" "unprognostic (1.97e-3)" "unprognostic (3.27e-2)" "unprognostic (1.88e-1)" "unprognostic (3.56e-3)" "unprognostic (7.42e-2)" "unprognostic (7.91e-3)" "unprognostic (2.01e-2)" "unprognostic (2.46e-3)" "unprognostic (9.13e-3)" "unprognostic (3.69e-2)" "unprognostic (1.41e-1)" "unprognostic (4.87e-2)" "unprognostic (1.89e-2)" "unprognostic (2.14e-2)" "unprognostic (3.05e-3)" "unprognostic (2.69e-2)" "unprognostic (5.58e-2)" 16.1 6.6 15.7 8.4 17.0 2.3 10.7 12.1 23.5 30.3 15.7 13.4 3.0 20.4 14.9 7.1 23.0 5.6 8.0 14.4 13.3 42.6 3.2 13.4 15.2 14.1 14.6 16.8 4.0 0.4 16.4 4.0 13.1 13.6 4.5 9.5 7.5 7.5 2.1 15.7 17.8 6.3 12.3 29.1 11.3 6.4 14.4 5.1 24.8 1.8 13.6 5.1 9.1 12.3 2.7 2.6 1.0 0.4 1.9 2.3 5.8 0.5 0.0 0.1 0.2 3.4 0.8 0.5 2.7 0.0 0.1 4.3 2.7 2.0 0.3 3.0 3.9 1.2 4.7 0.3 16.1 0.4 2.1 30.6 11.4 0.5 1.7 0.2 0.6 2.5 0.8 0.3 0.0 1.4 0.3 3.0 0.6 0.3 0.8 0.4 0.3 2.8 2.3 0.6 0.3 0.5 6.2 7.0 1.3 7.9 0.2 4.8 0.5 0.7 2.3 0.2 0.3 1.3 0.1 0.3 1.4 1.4 0.6 0.8 0.5 0.3 0.2 0.3 0.1 0.4 0.1 0.2 0.1 0.5 0.2 0.2 2.5 0.3 0.2 5.4 0.3 0.1 15.7 17.0 12.1 23.5 14.4 13.3 14.1 14.6 13.1 12.3 14.4 12.3 0.4 0.0 2.6 119.8 0.3 2.0 0.7 5.1 0.6 1.2 1.8 1.4 1.9 7.2 4.8 5.5 8.4 0.5 5.7 0.4 0.0 4.0 0.3 11.8 37.9 3.4 0.0 0.0 0.3 0.0 1.1 8.3 0.5 16.1 0.0 0.2 3.3 0.1 1.2 0.0 0.9 0.4 2.0 0.3 1.6 1.7 34.5 1.8 1.8 10.3 1.6 15.7 0.0 3.0 0.3 0.4 0.0 44.0 0.2 1.4 0.2 10.2 3.7 3.0 6.6 1.4 1.8 0.6 0.1 0.8 3.0 0.4 0.7 0.1 1.0 0.4 PAPSS2 ATPSK2 ENSG00000198682 "3'-phosphoadenosine 5'-phosphosulfate synthase 2" O95340 10 87659613-87747705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 135.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 240.4;Distal enterocytes: 202.4;Hepatocytes: 111.5;Proximal enterocytes: 181.3;Theca cells: 96.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.0;myeloid DC: 2.1;non-classical monocyte: 7.7" "Group enriched" "Detected in many" 7 "dendritic cells: 2.1;monocytes: 7.7" "Cell line enhanced" "Detected in many" "BJ: 189.8;fHDF/TERT166: 473.2;HHSteC: 196.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071224, HPA075267" Enhanced Approved Mitochondria No No 16000 "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA071224: AB_2686366, HPA075267: " "unprognostic (3.98e-3)" "unprognostic (7.06e-2)" "unprognostic (4.95e-3)" "unprognostic (1.02e-1)" "unprognostic (2.67e-1)" "unprognostic (1.61e-2)" "unprognostic (4.96e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.33e-6)" "unprognostic (3.50e-2)" "prognostic favorable (6.58e-4)" "unprognostic (1.14e-1)" "unprognostic (4.90e-2)" "unprognostic (6.72e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.21e-5)" "unprognostic (3.46e-3)" 33.3 135.2 6.3 26.6 7.0 2.0 20.9 6.2 9.5 17.8 6.2 79.9 29.5 8.5 3.1 10.2 12.4 20.7 11.6 5.8 6.2 23.8 77.0 70.4 11.0 6.9 6.6 27.5 26.1 2.1 3.0 58.5 7.5 6.7 64.3 2.3 16.4 3.4 4.7 3.5 61.8 16.7 6.8 8.5 9.2 11.7 8.0 3.0 21.3 8.7 14.8 16.6 11.5 7.2 19.9 20.0 6.4 0.3 129.4 164.8 0.3 189.8 157.7 110.4 79.9 1.0 4.1 0.1 9.8 473.2 3.5 8.5 13.9 13.3 125.2 0.2 10.0 8.8 13.4 0.1 196.5 0.2 3.8 58.7 0.3 63.7 5.2 135.6 94.2 1.4 0.0 89.4 79.2 74.1 0.1 0.7 7.4 4.8 24.1 0.4 0.1 0.4 117.5 8.7 0.9 1.6 92.5 3.3 1.1 12.6 13.5 5.3 120.0 38.2 22.5 131.5 13.9 0.3 1.0 0.3 18.3 0.2 0.2 0.0 1.1 0.0 0.0 4.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.6 0.0 7.7 0.0 0.0 0.8 6.3 7.0 6.2 9.5 5.8 6.2 6.9 6.6 7.5 6.8 8.0 7.2 49.5 240.4 38.2 3.6 2.6 2.3 0.9 18.0 1.8 0.2 11.5 4.7 4.4 8.6 13.8 9.2 0.0 0.5 0.8 202.4 13.7 6.4 1.2 2.6 18.7 23.2 12.6 5.2 22.2 30.2 0.8 36.1 15.3 11.6 0.0 20.3 36.0 111.5 11.5 0.0 27.6 26.5 4.1 29.8 50.7 0.8 17.4 51.0 1.8 30.0 5.2 1.3 0.0 21.6 1.0 19.4 46.1 5.3 3.1 2.1 181.3 9.8 3.4 0.0 13.1 1.0 20.4 1.2 0.7 1.1 1.3 1.4 1.7 96.4 74.3 1.1 PAQR5 "FLJ20190, MPRG" ENSG00000137819 "Progestin and adipoQ receptor family member 5" Q9NXK6 15 69298912-69407780 "Predicted membrane proteins" "Differentiation, Oogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 52.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 32.9;Distal tubular cells: 46.9;Early spermatids: 38.2;granulocytes: 67.2;Late spermatids: 123.0;Proximal tubular cells: 42.3" "Cancer enhanced" "Detected in many" "renal cancer: 8.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "basophil: 1.1" "Lineage enriched" "Detected in single" 7 "granulocytes: 1.1" "Cell line enhanced" "Detected in many" "A549: 38.1;CAPAN-2: 46.4;fHDF/TERT166: 33.1;HMC-1: 79.8;U-87 MG: 33.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076729 Approved Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA076729: AB_2686813" "unprognostic (4.47e-2)" "unprognostic (3.11e-2)" "unprognostic (1.46e-1)" "unprognostic (4.05e-4)" "unprognostic (1.53e-1)" "unprognostic (8.28e-2)" "unprognostic (3.58e-3)" "unprognostic (6.12e-3)" "unprognostic (1.47e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (2.00e-1)" "prognostic favorable (1.47e-14)" "unprognostic (5.64e-2)" "unprognostic (1.73e-1)" "unprognostic (4.16e-4)" "unprognostic (4.94e-2)" 0.6 16.0 3.5 2.6 2.8 1.2 1.2 2.7 3.0 1.7 12.0 19.0 2.3 1.0 0.2 12.4 0.9 2.0 0.8 3.1 2.8 52.9 1.1 9.1 0.3 3.4 3.1 0.6 5.1 11.3 0.8 1.6 4.0 0.6 16.2 1.9 1.8 3.7 0.2 4.9 8.0 0.9 2.8 0.4 7.7 2.4 4.4 0.2 0.8 0.2 2.1 3.6 2.9 2.9 11.7 38.1 0.8 0.8 1.6 4.2 0.3 3.7 22.2 4.3 9.1 2.2 46.4 0.1 5.9 33.1 3.7 0.7 10.9 0.6 7.4 0.1 1.7 6.9 5.6 0.8 2.9 0.2 79.8 2.2 1.7 19.4 20.7 5.5 0.0 0.2 0.1 0.7 18.4 1.6 0.2 0.2 2.6 6.1 3.2 0.1 0.6 2.2 16.6 0.9 3.3 0.7 6.0 2.3 3.1 2.1 1.0 2.8 0.6 13.1 4.2 1.1 0.4 0.2 0.3 0.1 33.1 0.1 3.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 3.5 2.8 2.7 3.0 3.1 2.8 3.4 3.1 4.0 2.8 4.4 2.9 0.1 12.8 21.0 1.0 0.5 0.9 1.3 0.4 1.2 0.7 1.3 0.8 0.7 32.9 0.9 20.2 0.0 0.0 0.0 31.1 46.9 19.0 38.2 0.7 0.1 1.9 0.0 0.0 0.5 0.4 0.0 2.8 2.0 1.5 67.2 2.2 0.0 0.0 3.7 0.0 0.7 4.8 0.0 0.3 0.7 123.0 0.9 1.8 0.0 20.6 0.0 5.9 0.0 1.0 0.5 2.6 6.9 1.2 0.0 1.4 26.8 42.3 0.8 0.1 6.6 0.1 0.6 0.5 0.5 15.1 1.8 0.1 0.4 19.6 13.7 0.8 PATL2 Pat1a ENSG00000229474 "PAT1 homolog 2" C9JE40 15 44665732-44711316 "Disease related genes, Human disease related genes, Predicted intracellular proteins" RNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.7;lymphoid tissue: 17.2" "Cell type enhanced" "Detected in many" "B-cells: 29.2;dendritic cells: 19.1;NK-cells: 51.5;Plasma cells: 15.7;T-cells: 29.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 21.6;memory CD4 T-cell: 6.0;memory CD8 T-cell: 17.7;naive CD8 T-cell: 12.8" "Lineage enriched" "Detected in many" 6 "T-cells: 21.6" "Cell line enriched" "Detected in some" 28 "U-266/70: 124.9" "Not detected" "Not detected" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (1.28e-2)" "unprognostic (8.59e-3)" "unprognostic (3.30e-3)" "unprognostic (5.55e-2)" "unprognostic (7.28e-2)" "unprognostic (1.11e-2)" "unprognostic (3.00e-3)" "unprognostic (7.82e-2)" "unprognostic (3.69e-1)" "unprognostic (1.75e-2)" "unprognostic (1.44e-2)" "unprognostic (9.48e-2)" "unprognostic (1.35e-3)" "unprognostic (2.27e-1)" "unprognostic (1.51e-1)" "unprognostic (1.20e-1)" "unprognostic (9.69e-4)" 0.9 1.1 0.8 7.7 1.1 7.7 1.3 0.6 0.8 0.3 1.5 2.1 2.4 1.1 1.7 0.6 1.4 2.3 0.7 0.7 0.8 0.5 1.7 3.9 17.2 1.8 1.1 0.9 0.6 0.4 0.2 1.0 1.1 0.8 2.5 0.1 2.5 0.6 0.3 2.7 3.2 0.8 0.9 13.9 3.2 0.5 1.2 3.6 0.7 0.0 10.8 2.1 0.2 1.4 0.2 0.0 0.0 0.1 0.0 1.1 2.8 0.1 0.4 0.9 0.9 0.6 1.2 0.9 0.1 0.3 1.8 1.3 0.1 0.2 0.5 2.1 0.0 1.2 0.0 0.1 0.5 0.5 0.7 1.2 0.1 0.5 0.3 0.2 0.0 1.4 0.2 4.5 0.3 0.3 0.1 1.4 0.4 0.1 0.1 1.8 0.0 0.5 0.1 0.4 0.1 0.0 0.0 1.3 0.1 0.2 0.1 0.9 0.6 0.3 0.0 0.8 0.0 124.9 4.3 0.4 1.2 3.1 0.4 1.5 0.3 2.6 21.6 0.7 3.2 3.3 6.0 17.7 0.7 3.5 3.6 12.8 1.6 2.7 0.5 0.6 0.9 3.7 0.8 1.1 0.6 0.8 0.7 0.8 1.8 1.1 1.1 0.9 1.2 1.4 1.4 3.2 1.7 1.6 29.2 0.9 0.6 0.5 0.6 0.0 0.6 0.6 11.7 0.0 0.4 0.0 0.0 0.2 19.1 2.0 0.0 0.4 0.3 2.4 1.0 1.8 0.0 3.0 0.3 0.6 0.5 1.9 8.2 0.8 0.0 1.2 1.4 1.0 2.0 0.0 0.4 1.4 0.0 4.8 2.3 0.0 0.3 5.6 0.0 3.7 5.2 0.0 51.5 0.5 1.3 0.4 0.3 0.0 15.7 0.6 2.2 0.4 8.5 0.0 0.0 1.0 2.6 0.1 0.4 1.4 0.9 0.3 29.8 1.8 0.9 1.3 PC PCB ENSG00000173599 "Pyruvate carboxylase" P11498 11 66848417-66958386 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Lipid biosynthesis, Lipid metabolism" "Ligase, Multifunctional enzyme" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 148.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 201.9;Late spermatids: 53.2" "Cancer enhanced" "Detected in all" "liver cancer: 37.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 57.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033742, HPA043922, HPA058765" Enhanced Enhanced Mitochondria Yes No 200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 15: Hepatocytes - Hemostasis" Mitochondria "CAB033742: AB_2283532, HPA043922: AB_2678732, HPA058765: AB_2683812" "unprognostic (2.10e-1)" "unprognostic (1.51e-1)" "unprognostic (1.36e-2)" "unprognostic (8.24e-3)" "unprognostic (3.67e-1)" "unprognostic (3.18e-2)" "unprognostic (2.97e-1)" "unprognostic (3.00e-1)" "unprognostic (3.63e-1)" "prognostic unfavorable (7.86e-5)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "prognostic favorable (8.22e-5)" "unprognostic (8.58e-3)" "unprognostic (5.67e-2)" "unprognostic (9.15e-3)" "unprognostic (1.05e-1)" 60.9 23.7 35.7 2.9 35.5 3.5 28.4 36.6 35.8 3.7 17.5 4.7 6.5 3.8 1.8 9.3 3.2 2.8 4.3 32.4 41.0 23.3 148.0 2.6 1.3 43.4 40.1 5.1 4.9 18.2 8.6 4.4 37.6 7.2 2.8 2.4 35.3 9.3 12.1 4.7 7.7 1.4 37.8 1.5 9.1 10.7 49.0 2.0 4.6 6.6 2.0 2.9 4.4 37.0 6.1 19.3 6.5 17.2 25.4 8.9 6.6 3.4 15.5 6.9 7.5 8.8 6.0 0.0 7.4 6.0 9.6 6.8 7.7 39.5 1.5 2.8 11.0 10.3 57.4 41.2 21.0 0.1 10.8 40.2 10.1 5.8 12.4 4.4 5.7 14.3 17.4 0.0 2.1 44.6 9.2 4.6 12.0 15.1 16.2 8.3 13.0 3.2 5.7 1.9 15.2 21.0 33.6 18.0 15.5 4.8 14.6 2.7 6.3 7.8 6.6 8.8 4.7 3.5 4.8 0.1 7.7 5.7 6.7 0.0 1.3 0.0 0.5 0.3 0.5 0.0 0.1 0.5 0.9 0.2 0.9 0.5 0.1 0.1 0.1 0.3 0.5 0.7 35.7 35.5 36.6 35.8 32.4 41.0 43.4 40.1 37.6 37.8 49.0 37.0 0.9 0.0 3.0 26.4 1.4 1.3 1.6 9.1 2.8 5.6 4.8 5.8 4.4 11.5 3.0 3.7 2.1 17.4 0.6 27.6 1.9 3.1 18.4 2.3 7.1 1.5 9.0 28.0 18.5 1.8 4.2 3.2 5.6 3.0 8.9 16.0 4.6 201.9 12.3 0.0 18.6 5.0 0.0 7.0 1.8 53.2 0.6 1.8 5.4 7.5 18.9 9.4 2.1 10.1 16.7 2.3 8.5 4.1 0.1 3.1 23.6 39.0 1.5 4.8 0.0 2.2 2.2 11.2 4.7 4.1 0.6 25.4 1.2 6.0 6.4 1.3 PCBD1 "DCOH, PCBD, PCD" ENSG00000166228 "Pterin-4 alpha-carbinolamine dehydratase 1" P61457 10 70882280-70888565 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis, Transcription, Transcription regulation" "Activator, Lyase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 429.5" "Cell type enhanced" "Detected in all" "Distal tubular cells: 453.9;Hepatocytes: 603.7;Proximal tubular cells: 877.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 527.8;Hep G2: 527.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037575, HPA061723" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 170000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 15: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Cytosol "HPA037575: AB_10671761, HPA061723: AB_2684594" "unprognostic (1.02e-1)" "unprognostic (5.05e-2)" "unprognostic (7.43e-2)" "unprognostic (3.69e-1)" "unprognostic (5.39e-2)" "unprognostic (4.80e-3)" "unprognostic (1.81e-1)" "unprognostic (1.47e-1)" "unprognostic (2.35e-1)" "unprognostic (2.40e-2)" "unprognostic (2.95e-1)" "unprognostic (5.63e-2)" "unprognostic (3.38e-2)" "unprognostic (9.26e-2)" "unprognostic (1.74e-1)" "unprognostic (5.76e-2)" "unprognostic (7.43e-3)" 77.3 102.9 115.0 31.0 111.8 21.8 67.9 111.9 140.7 58.0 114.1 83.9 54.4 48.2 91.2 54.3 111.5 47.4 152.3 109.3 136.9 165.1 429.5 57.9 31.1 125.4 138.5 64.2 174.9 135.1 61.5 33.4 139.4 73.8 88.3 48.6 49.9 78.4 109.7 25.7 64.0 75.6 119.7 25.6 84.8 20.0 131.8 25.8 86.3 109.1 35.8 69.3 39.2 118.9 158.3 374.3 21.4 223.8 80.9 76.0 29.4 50.0 84.5 77.7 61.6 527.8 270.3 32.2 141.4 56.3 57.9 101.7 138.9 81.3 53.2 86.2 251.9 28.6 57.5 527.1 84.9 28.5 99.2 74.1 88.5 76.5 35.8 114.1 212.3 19.9 57.1 2.8 55.2 270.2 3.5 94.7 30.1 420.5 346.0 15.1 29.7 103.6 328.6 164.7 94.0 158.8 41.5 277.1 111.5 59.9 81.1 53.8 86.2 12.7 102.9 18.9 123.8 1.1 6.7 1.1 68.3 93.1 19.5 0.2 24.8 8.7 19.6 47.1 15.3 25.7 25.8 28.3 49.6 10.9 8.4 17.1 1.6 19.6 34.4 35.8 41.1 18.7 115.0 111.8 111.9 140.7 109.3 136.9 125.4 138.5 139.4 119.7 131.8 118.9 25.5 41.7 91.5 8.5 25.9 49.8 169.1 88.2 103.0 39.0 197.9 249.6 151.5 138.7 86.0 187.6 6.2 124.6 18.5 113.8 453.9 185.0 2.3 138.7 49.3 40.8 176.4 36.2 4.9 169.9 81.6 82.2 86.6 175.3 31.1 64.6 37.9 603.7 180.3 35.3 8.5 313.3 65.1 79.9 55.7 11.2 67.4 73.1 78.2 5.6 68.0 153.0 22.6 9.0 4.6 154.8 164.7 95.5 35.1 212.7 232.1 877.7 78.4 33.2 85.5 57.2 63.3 4.4 12.3 147.8 45.7 77.6 32.6 95.9 230.2 187.5 PCCB ENSG00000114054 "Propionyl-CoA carboxylase subunit beta" P05166 3 136250340-136337896 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 202.1" "Cell type enhanced" "Detected in all" "Early spermatids: 316.7;Late spermatids: 159.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036939, HPA036940" Enhanced "Intracellular and membrane" NA NA 120000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "HPA036939: AB_10671366, HPA036940: AB_10669779" "unprognostic (2.74e-1)" "unprognostic (7.88e-3)" "unprognostic (3.99e-2)" "unprognostic (2.89e-2)" "unprognostic (2.75e-2)" "unprognostic (1.11e-1)" "unprognostic (1.05e-2)" "unprognostic (1.50e-1)" "unprognostic (2.31e-2)" "unprognostic (2.47e-2)" "unprognostic (1.74e-1)" "unprognostic (1.05e-1)" "prognostic favorable (6.47e-7)" "unprognostic (2.43e-2)" "unprognostic (2.64e-1)" "unprognostic (3.50e-1)" "unprognostic (4.13e-1)" 34.4 75.1 23.3 15.2 33.6 37.9 27.5 31.4 29.3 17.5 35.5 43.6 38.1 13.8 13.9 26.3 19.2 17.0 94.6 23.6 28.5 88.9 202.1 14.8 16.2 31.1 29.4 12.1 32.0 57.0 15.6 19.6 30.4 23.7 41.9 17.2 23.6 21.7 83.8 15.1 27.5 22.6 27.1 12.7 26.1 38.8 29.8 21.1 37.9 91.4 20.7 20.5 11.4 47.8 64.8 45.8 42.4 64.4 30.2 34.5 75.4 33.0 35.5 49.1 69.6 67.9 44.7 80.3 89.4 46.6 44.0 35.1 50.3 44.0 69.4 47.8 43.0 140.8 49.5 101.4 66.4 107.3 60.2 40.8 41.4 31.0 69.4 30.5 56.1 131.6 104.5 41.0 38.0 123.1 109.3 63.1 36.0 96.8 40.9 29.3 34.6 116.6 89.9 69.4 84.0 62.9 84.4 48.9 77.5 35.2 98.3 62.9 42.0 24.5 26.0 69.2 29.6 78.3 70.0 66.9 34.9 41.7 29.9 7.3 29.5 7.5 22.6 30.8 25.4 21.7 14.7 23.2 44.6 19.8 15.1 18.7 2.7 25.9 28.7 38.5 14.8 22.6 23.3 33.6 31.4 29.3 23.6 28.5 31.1 29.4 30.4 27.1 29.8 47.8 5.6 9.6 14.0 16.0 9.2 4.1 9.4 37.9 3.4 16.0 12.5 5.3 51.1 8.6 28.4 20.2 10.4 57.1 8.0 15.1 39.2 24.6 316.7 14.1 9.5 8.1 9.1 53.2 16.5 14.0 27.1 13.6 14.8 14.1 29.2 18.1 9.3 76.3 35.1 11.8 22.7 15.1 24.4 11.7 5.2 159.0 13.7 11.4 19.6 16.9 16.5 11.8 10.3 22.1 50.9 14.4 16.7 10.9 22.6 10.4 19.2 97.3 23.6 13.2 13.1 13.6 13.1 11.3 29.0 16.2 3.3 50.9 9.9 52.8 25.1 12.2 PCDH12 VE-cadherin-2 ENSG00000113555 "Protocadherin 12" Q9NPG4 5 141943581-141969741 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Epilepsy, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 30.2" "Group enriched" "Detected in some" 4 "Adipocytes: 38.5;Endothelial cells: 40.0;Hepatic stellate cells: 41.0;Hofbauer cells: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 4.6" "Lineage enriched" "Detected in single" 41 "monocytes: 4.6" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 25.9;Karpas-707: 66.5;U-937: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051242 Uncertain "Secreted to blood" NA NA 14000000 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA051242: AB_2681402" "unprognostic (6.62e-2)" "unprognostic (6.94e-2)" "unprognostic (4.74e-3)" "unprognostic (4.12e-2)" "unprognostic (3.99e-1)" "unprognostic (3.25e-1)" "unprognostic (4.35e-1)" "unprognostic (1.88e-2)" "unprognostic (4.29e-2)" "unprognostic (2.76e-1)" "unprognostic (9.99e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.11e-2)" "unprognostic (5.21e-2)" "unprognostic (9.37e-2)" "unprognostic (9.33e-2)" 13.4 5.0 0.8 2.5 0.9 0.5 4.9 2.5 1.7 2.7 1.2 2.0 2.0 2.8 0.4 2.1 2.1 4.0 10.8 0.6 0.8 6.0 4.0 15.5 2.6 0.5 0.3 1.7 1.4 2.9 3.6 30.2 0.6 1.9 1.3 1.6 1.4 2.3 4.0 1.7 2.1 5.2 0.3 18.6 2.0 1.1 1.4 0.8 6.5 5.1 1.0 3.2 1.9 0.3 0.1 0.1 1.9 0.5 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.1 5.0 0.1 0.6 0.1 0.0 0.0 0.0 0.4 0.6 1.4 0.2 0.1 0.2 0.5 0.2 0.0 0.0 0.4 0.0 0.4 25.9 0.3 0.0 66.5 0.0 0.4 0.1 0.3 0.5 0.0 0.3 0.5 0.2 3.0 0.0 0.1 0.3 0.7 0.1 0.1 0.3 0.2 0.0 1.8 1.8 0.6 0.1 0.9 0.1 0.4 0.4 0.1 0.4 11.7 2.2 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.8 0.9 2.5 1.7 0.6 0.8 0.5 0.3 0.6 0.3 1.4 0.3 38.5 0.0 1.1 0.0 0.5 0.6 0.0 0.0 1.2 1.3 0.1 0.1 4.0 0.0 0.0 0.0 2.1 0.3 0.3 0.0 3.9 0.1 1.7 0.1 0.1 40.0 0.0 0.0 0.2 0.0 0.3 0.9 0.0 0.1 1.3 0.0 41.0 0.5 34.6 0.0 0.2 0.0 0.0 8.5 0.3 2.5 0.0 1.5 1.8 6.5 0.3 0.5 0.0 1.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.4 0.0 0.4 0.0 0.7 1.0 0.0 0.2 0.2 0.3 0.5 0.2 1.4 0.0 0.2 PDCD1 "CD279, hSLE1, PD-1, PD1, SLEB2" ENSG00000188389 "Programmed cell death 1" Q15116 2 241849884-241858894 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Apoptosis, Immunity" "FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 6.7;lymphoid tissue: 16.1" "Group enriched" "Detected in some" 4 "Plasma cells: 9.5;T-cells: 34.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "midbrain: 1.4" "Group enriched" "Detected in many" 5 "gdT-cell: 4.4;MAIT T-cell: 4.8;memory CD4 T-cell: 8.7;memory CD8 T-cell: 12.4;T-reg: 4.3" "Lineage enriched" "Detected in single" 55 "T-cells: 12.4" "Cell line enhanced" "Detected in some" "JURKAT: 1.5;MOLT-4: 2.4;RPMI-8226: 6.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035981, CAB038418, CAB076386" Enhanced NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB038418: AB_1160824, CAB076386: AB_881954, HPA035981: AB_10669664" "unprognostic (2.90e-3)" "unprognostic (4.50e-3)" "unprognostic (7.78e-2)" "prognostic favorable (9.44e-5)" "unprognostic (7.18e-3)" "unprognostic (1.31e-3)" "unprognostic (3.83e-2)" "unprognostic (7.33e-2)" "unprognostic (5.82e-3)" "unprognostic (3.75e-2)" "unprognostic (6.57e-2)" "unprognostic (3.94e-1)" "prognostic unfavorable (3.48e-7)" "unprognostic (1.20e-2)" "unprognostic (3.10e-1)" "unprognostic (5.35e-2)" "unprognostic (5.06e-3)" 1.2 0.3 0.0 3.2 0.2 0.9 0.4 0.0 0.1 0.6 0.2 0.8 0.3 0.4 0.0 0.8 0.6 0.3 6.7 0.1 0.1 0.7 0.4 1.8 16.1 0.1 1.4 0.2 0.3 0.0 1.5 0.0 0.2 0.7 0.1 0.0 1.0 0.2 0.1 0.3 3.8 0.2 0.1 7.0 1.8 0.3 0.4 3.1 1.5 0.0 4.0 1.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 0.3 2.4 0.0 0.0 0.0 0.0 0.0 0.1 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 4.8 0.2 8.7 12.4 0.0 0.0 0.8 1.2 0.0 0.0 0.0 0.0 4.3 2.1 0.0 0.2 0.0 0.1 0.1 0.1 0.1 1.4 0.2 0.1 0.4 0.2 0.4 0.0 0.6 0.0 3.6 0.4 0.3 0.0 0.0 0.0 0.3 0.5 0.6 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 5.3 0.0 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.3 1.4 0.0 0.0 1.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.6 0.0 34.7 0.0 0.0 0.1 PDE10A ENSG00000112541 "Phosphodiesterase 10A" Q9Y233 6 165327287-165988078 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 67.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 204.7;Inhibitory neurons: 209.6;Microglial cells: 89.0;Oligodendrocyte precursor cells: 48.7;Oligodendrocytes: 51.8" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "basal ganglia: 67.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 9.0;LHCN-M2: 12.5;RT4: 6.9;SH-SY5Y: 8.1;TIME: 11.3;U-2 OS: 7.0" "Region enriched" "Detected in all" 11 "basal ganglia: 350.1" "Region enriched" "Detected in all" 5 "basal ganglia: 194.1" "CAB045998, HPA047200" Supported NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB045998: AB_2162589, HPA047200: AB_2679981" "unprognostic (1.02e-1)" "unprognostic (3.63e-2)" "unprognostic (3.58e-2)" "unprognostic (2.91e-1)" "unprognostic (1.20e-1)" "unprognostic (1.25e-1)" "unprognostic (1.76e-1)" "unprognostic (1.23e-1)" "unprognostic (9.36e-2)" "unprognostic (6.03e-2)" "unprognostic (3.79e-2)" "unprognostic (9.24e-2)" "prognostic unfavorable (4.44e-7)" "unprognostic (3.59e-3)" "unprognostic (2.37e-2)" "unprognostic (3.44e-2)" "unprognostic (5.90e-3)" 2.6 1.3 3.1 0.8 67.2 0.0 2.3 5.5 10.7 1.3 0.0 1.0 0.2 2.0 2.4 0.4 2.4 1.5 3.6 2.1 2.5 3.8 0.3 1.0 0.5 1.6 2.3 2.3 0.5 0.5 2.7 2.5 0.9 1.7 0.2 1.9 0.4 1.7 0.4 0.3 0.7 2.1 0.5 1.4 1.1 3.4 9.6 0.3 6.0 0.5 0.4 3.2 0.9 0.1 0.0 2.4 5.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.3 0.8 0.0 0.0 0.0 3.8 0.1 2.2 0.0 0.0 0.1 3.9 0.0 9.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 5.5 0.0 0.0 0.0 12.5 0.3 0.9 0.0 1.1 0.0 4.7 1.5 5.8 0.0 5.9 6.9 1.8 8.1 0.0 0.0 0.4 0.7 0.0 0.0 11.3 0.1 7.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 67.2 5.5 10.7 2.1 2.5 1.6 2.3 0.9 0.5 9.6 0.1 13.8 0.0 0.0 10.4 0.1 0.4 3.3 0.4 0.0 7.2 0.3 0.3 7.3 0.0 1.2 5.5 2.1 7.8 0.0 0.0 3.9 2.0 14.3 0.2 1.7 13.4 0.0 0.0 204.7 0.0 6.1 6.6 1.1 0.4 1.3 0.1 7.9 0.0 0.8 16.8 209.6 0.0 0.0 0.0 0.0 14.9 0.0 0.2 1.8 89.0 0.0 12.6 0.0 48.7 51.8 0.1 0.0 0.4 0.0 17.9 0.0 7.2 0.9 1.1 0.0 12.4 5.0 8.8 2.1 0.1 0.3 2.9 0.1 1.6 0.1 6.9 PDE2A ENSG00000186642 "Phosphodiesterase 2A" O00408 11 72576141-72674591 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 197.0" "Group enriched" "Detected in many" 6 "Adipocytes: 114.9;Endothelial cells: 58.5;Enteroendocrine cells: 34.4;Excitatory neurons: 70.1;Hepatic stellate cells: 118.2;Inhibitory neurons: 35.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 75.1;basal ganglia: 84.7;cerebral cortex: 102.1;hippocampal formation: 84.4;white matter: 48.3" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.8;T-cells: 7.3" "Cell line enriched" "Detected in some" 8 "HeLa: 513.6" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 5 "amygdala: 83.5;basal ganglia: 146.9;cerebral cortex: 90.5;hippocampal formation: 94.0" "CAB009752, HPA031192" Enhanced Supported Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB009752: AB_2268159, HPA031192: AB_2673781" "unprognostic (1.92e-1)" "unprognostic (1.52e-3)" "unprognostic (4.58e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-1)" "unprognostic (2.50e-1)" "prognostic favorable (1.76e-6)" "unprognostic (3.06e-2)" "unprognostic (1.35e-1)" "unprognostic (3.01e-3)" "unprognostic (3.13e-3)" "unprognostic (1.50e-2)" "unprognostic (1.77e-2)" "unprognostic (2.85e-3)" "unprognostic (6.31e-2)" "unprognostic (7.72e-2)" "unprognostic (7.96e-4)" 89.2 44.1 75.1 5.1 84.7 4.7 83.6 0.0 102.1 38.1 0.0 34.6 6.0 27.2 8.3 18.6 39.3 22.7 41.1 84.4 7.0 32.5 19.4 12.6 6.7 6.4 5.1 11.6 6.9 5.5 11.8 12.0 10.1 20.7 8.9 3.0 9.2 10.7 16.8 18.1 18.7 18.5 0.0 197.0 17.1 7.4 17.9 3.8 24.1 28.9 3.5 28.8 27.1 48.3 0.3 0.2 0.7 0.2 0.2 0.1 0.3 0.1 0.2 0.2 0.4 0.4 2.5 0.8 12.2 0.2 1.9 0.2 0.9 0.1 0.1 0.1 0.1 0.0 513.6 0.8 0.9 0.0 7.8 0.1 1.1 2.7 20.5 1.1 11.3 0.5 0.8 0.9 0.1 0.0 0.2 0.2 7.4 0.2 14.0 0.0 0.2 1.4 0.1 0.3 44.5 2.4 0.4 0.2 2.2 0.7 0.3 0.1 65.2 0.1 9.4 3.5 0.4 0.4 0.2 0.1 3.9 0.1 0.6 0.0 0.6 0.0 7.3 0.8 4.2 2.8 4.3 4.3 1.0 1.8 2.7 2.3 0.1 0.0 0.4 0.0 1.8 1.5 75.1 84.7 0.0 102.1 84.4 7.0 6.4 5.1 10.1 0.0 17.9 48.3 114.9 0.0 0.5 2.0 0.7 2.5 0.1 0.0 0.0 4.9 0.6 1.0 7.8 0.0 0.0 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.6 0.0 0.1 58.5 34.4 5.3 70.1 0.0 0.3 2.1 0.0 0.1 1.3 0.1 118.2 2.1 0.5 1.7 35.6 1.2 0.0 9.4 8.2 2.5 0.3 4.9 1.8 11.2 0.0 0.0 0.0 9.0 5.7 0.1 0.0 0.4 1.5 0.1 0.0 0.1 0.0 0.4 0.0 1.8 6.6 4.8 2.5 0.5 2.8 0.0 0.6 0.2 0.1 0.3 PDE5A ENSG00000138735 "Phosphodiesterase 5A" O76074 4 119494397-119628804 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 66.1;Inhibitory neurons: 58.3;Oligodendrocyte precursor cells: 56.8;Peritubular cells: 104.9;Smooth muscle cells: 80.9" "Group enriched" "Detected in all" 4 "prostate cancer: 7.0;thyroid cancer: 27.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 47.5;HHSteC: 65.9;hTERT-RPE1: 24.6" "Region enhanced" "Detected in all" "cerebellum: 18.2" "Low region specificity" "Detected in all" "HPA004729, HPA012873" Approved Approved Cytosol NA NA 850000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA004729: AB_1079588, HPA012873: AB_1855124" "unprognostic (6.95e-2)" "prognostic favorable (5.20e-4)" "unprognostic (1.28e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (7.36e-2)" "unprognostic (2.58e-2)" "unprognostic (2.29e-2)" "unprognostic (6.97e-2)" "unprognostic (2.05e-2)" "unprognostic (2.54e-1)" "unprognostic (2.16e-2)" "unprognostic (1.52e-2)" "unprognostic (8.98e-2)" "unprognostic (8.71e-3)" "prognostic unfavorable (1.17e-4)" 15.4 11.3 0.9 10.9 3.5 2.1 9.6 4.9 3.7 32.7 12.6 37.0 15.5 14.4 41.5 41.3 22.9 10.4 12.8 1.4 3.6 5.9 1.5 22.1 6.4 4.9 8.2 5.4 12.4 8.3 3.5 13.2 5.2 59.8 25.9 9.6 9.8 49.8 6.9 5.0 18.9 11.4 0.0 5.8 9.6 9.4 3.4 3.7 16.8 5.6 3.5 14.6 15.8 1.9 16.7 0.8 11.0 1.2 3.7 5.5 1.9 10.7 47.5 0.5 1.0 1.0 1.3 1.6 0.5 13.4 3.0 5.8 3.5 1.7 1.3 0.4 7.4 18.5 2.6 0.9 65.9 3.9 1.7 6.1 3.3 1.1 0.1 24.6 1.4 3.7 2.0 2.9 1.6 0.9 5.0 0.6 2.3 1.8 2.8 0.7 5.9 4.3 4.1 4.9 4.3 8.8 13.0 15.3 1.3 8.1 2.7 2.1 2.5 6.2 5.2 3.4 1.5 4.1 2.0 1.5 5.9 1.0 0.9 0.0 0.0 0.0 0.1 0.0 0.5 0.4 0.3 0.1 0.0 0.3 0.1 0.2 0.4 0.2 0.1 0.1 0.1 1.2 0.9 3.5 4.9 3.7 1.4 3.6 4.9 8.2 5.2 0.0 3.4 1.9 7.8 6.4 3.9 19.9 1.3 3.4 2.8 1.1 5.7 8.1 11.0 8.4 5.5 14.3 3.7 1.8 14.6 0.4 0.9 15.5 0.0 15.8 30.6 5.0 12.6 7.8 2.4 0.0 66.1 2.9 0.3 28.1 1.1 3.9 1.3 1.6 0.7 0.9 0.3 5.0 58.3 9.5 2.0 0.0 3.5 11.5 20.8 11.3 5.4 40.3 1.3 28.5 2.1 56.8 41.1 3.9 10.3 104.9 1.4 3.6 7.9 0.5 0.8 5.8 19.7 5.5 80.9 5.4 6.3 3.5 2.4 0.3 1.7 7.0 11.1 2.6 PDIA5 "FLJ30401, PDIR" ENSG00000065485 "Protein disulfide isomerase family A member 5" Q14554 3 123067025-123225227 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 80.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 133.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 12.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030353, HPA030355" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" "Intracellular and membrane" NA NA 4700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Golgi apparatus" "Nucleoli fibrillar center" "HPA030353: AB_10599734, HPA030355: AB_10602200" "unprognostic (8.81e-2)" "unprognostic (2.25e-2)" "unprognostic (8.93e-2)" "prognostic favorable (4.55e-4)" "unprognostic (4.34e-2)" "unprognostic (2.10e-2)" "unprognostic (7.38e-2)" "unprognostic (2.41e-1)" "unprognostic (3.21e-2)" "unprognostic (4.02e-2)" "unprognostic (1.55e-1)" "unprognostic (2.26e-3)" "prognostic unfavorable (8.09e-11)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (1.06e-2)" "unprognostic (4.06e-3)" 17.9 23.6 0.3 15.2 0.3 17.9 13.8 0.2 1.4 14.5 2.7 20.1 13.9 12.4 30.2 6.1 14.0 19.6 9.9 0.6 0.8 14.5 80.2 17.7 11.1 0.5 0.6 11.5 26.6 10.7 12.7 47.4 0.4 32.3 25.0 4.2 13.7 7.9 4.2 8.8 12.8 17.0 0.3 10.1 33.4 15.3 0.9 4.5 30.8 4.3 12.0 17.9 9.5 0.7 24.0 14.6 17.7 21.5 80.3 71.9 95.0 44.9 74.5 24.5 66.9 47.8 21.6 0.0 57.6 69.9 15.7 12.5 7.8 27.4 25.7 1.1 8.8 10.4 3.9 56.7 33.2 26.5 1.4 62.3 40.2 16.6 34.5 26.1 84.0 10.1 13.6 60.4 16.9 29.6 7.2 31.3 13.1 54.5 15.6 6.7 13.0 67.5 20.7 13.9 19.3 11.4 22.0 24.0 40.4 28.7 21.4 32.3 47.2 6.2 19.5 29.4 12.3 18.1 5.0 10.8 20.2 21.0 21.5 0.0 9.3 0.3 1.4 2.4 2.3 3.5 1.0 0.8 5.5 1.1 0.6 0.6 0.2 0.5 0.5 12.8 0.0 2.3 0.3 0.3 0.2 1.4 0.6 0.8 0.5 0.6 0.4 0.3 0.9 0.7 17.2 19.2 30.7 2.6 5.6 5.0 6.0 6.4 3.4 13.1 6.9 4.7 2.7 35.8 11.3 5.5 39.6 41.8 3.1 5.4 0.0 32.2 1.6 5.4 13.1 24.3 8.4 5.5 9.6 28.6 133.6 20.7 30.5 21.1 3.8 7.3 37.5 50.1 12.1 0.0 7.1 36.9 0.0 7.8 5.5 2.0 24.2 4.4 8.8 5.6 5.0 2.3 0.0 1.0 2.5 11.9 7.6 22.2 40.1 18.1 3.5 5.3 6.4 28.4 13.1 3.6 17.6 1.3 1.5 3.4 4.1 50.2 3.1 23.3 15.1 4.5 PDIK1L CLIK1L ENSG00000175087 "PDLIM1 interacting kinase 1 like" Q8N165 1 26111165-26125555 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064157 Supported Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA064157: " "unprognostic (1.09e-1)" "unprognostic (1.81e-3)" "unprognostic (2.99e-3)" "unprognostic (2.52e-2)" "unprognostic (2.54e-1)" "unprognostic (1.34e-3)" "unprognostic (3.93e-2)" "unprognostic (1.72e-3)" "unprognostic (7.29e-3)" "unprognostic (1.08e-1)" "unprognostic (2.42e-2)" "unprognostic (3.59e-1)" "unprognostic (1.34e-2)" "unprognostic (4.24e-3)" "unprognostic (2.94e-1)" "unprognostic (4.47e-1)" "unprognostic (1.78e-2)" 3.2 3.4 4.4 4.5 4.0 16.6 8.2 6.6 5.1 5.9 2.7 6.9 7.1 4.4 4.6 4.9 5.4 3.9 3.3 4.1 5.2 6.0 8.1 4.6 6.5 3.9 4.0 6.5 7.8 7.0 2.6 3.4 4.8 4.7 7.3 8.3 6.3 5.0 4.8 5.5 5.6 3.6 3.8 4.6 7.3 5.0 4.9 8.6 15.4 5.2 6.3 4.6 3.2 4.9 7.9 2.9 7.5 9.8 2.7 3.8 2.6 2.3 2.7 5.2 3.3 2.0 11.2 17.8 6.3 2.6 4.0 5.6 11.2 4.0 4.4 6.1 7.7 15.3 4.3 2.2 4.7 15.6 9.0 2.2 5.9 4.6 8.5 3.5 4.8 15.3 18.0 16.8 1.8 4.8 23.5 7.4 3.5 9.5 4.7 12.7 7.3 19.2 3.7 6.1 13.3 10.8 8.2 10.0 10.5 2.0 5.4 5.4 4.4 5.5 5.2 7.0 6.9 23.8 26.5 12.0 5.9 19.2 5.0 10.5 3.8 3.3 4.8 3.6 4.5 4.9 6.6 5.3 7.3 4.2 7.0 5.6 0.3 4.4 5.1 2.8 7.9 4.0 4.4 4.0 6.6 5.1 4.1 5.2 3.9 4.0 4.8 3.8 4.9 4.9 6.4 9.6 4.2 5.9 6.2 3.2 1.7 3.5 7.4 18.6 8.6 3.9 2.3 7.2 7.0 1.8 0.0 3.9 2.7 6.5 0.0 3.7 1.3 3.2 5.7 5.0 13.1 6.3 13.7 4.0 0.7 3.8 7.1 4.9 7.0 6.3 5.0 11.1 4.1 23.5 15.4 8.0 4.1 6.3 5.9 0.5 2.5 4.6 3.6 5.6 3.1 11.0 0.0 10.1 12.1 2.9 3.3 3.0 14.0 3.5 4.5 7.5 8.4 11.7 0.0 2.9 3.6 14.0 11.7 14.5 7.4 1.6 5.4 3.0 8.7 3.0 PDK2 PDHK2 ENSG00000005882 "Pyruvate dehydrogenase kinase 2" Q15119 17 50094737-50112152 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 216.2;tongue: 285.0" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 123.0;Proximal tubular cells: 131.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008287 Supported Approved Nucleoplasm,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Mitochondria" "HPA008287: AB_1079589" "unprognostic (2.74e-2)" "prognostic favorable (5.87e-4)" "unprognostic (1.16e-1)" "unprognostic (2.43e-3)" "unprognostic (1.22e-1)" "unprognostic (9.63e-3)" "unprognostic (9.80e-3)" "unprognostic (8.39e-3)" "unprognostic (3.19e-2)" "unprognostic (1.25e-1)" "unprognostic (1.17e-2)" "unprognostic (2.21e-1)" "prognostic favorable (9.59e-5)" "unprognostic (3.81e-1)" "unprognostic (2.54e-1)" "unprognostic (5.33e-1)" "unprognostic (1.55e-1)" 40.8 63.8 49.9 8.7 51.2 5.0 26.4 65.7 58.2 30.5 37.1 42.7 28.1 29.4 124.4 21.8 24.3 18.0 116.6 50.6 41.8 62.7 50.8 15.3 10.1 40.8 44.0 48.2 44.3 40.7 17.0 14.7 41.8 23.5 21.5 14.7 25.7 27.4 216.2 26.0 32.5 25.7 40.8 18.4 33.7 13.7 44.6 12.6 27.3 285.0 9.2 30.9 22.2 44.6 12.4 17.5 20.6 18.5 21.2 16.5 2.2 13.2 19.3 19.3 18.5 1.7 13.2 15.5 21.7 37.0 13.0 6.4 13.7 5.3 18.8 30.6 19.3 14.0 17.1 13.2 11.3 0.0 15.0 33.6 19.6 12.5 0.9 33.7 17.2 20.0 5.7 15.0 11.0 15.8 11.8 0.0 4.5 37.2 17.1 17.5 45.8 21.1 10.4 10.4 13.8 20.7 18.7 5.9 9.0 25.0 35.0 13.7 8.8 22.5 18.4 16.0 10.1 29.4 29.9 8.2 33.3 4.9 15.4 14.3 16.2 8.9 16.2 12.9 12.8 12.9 14.8 18.0 18.4 13.8 17.2 18.0 2.6 22.9 14.1 25.8 22.4 17.4 49.9 51.2 65.7 58.2 50.6 41.8 40.8 44.0 41.8 40.8 44.6 44.6 17.9 9.6 10.3 18.3 12.1 15.2 12.3 12.4 17.6 19.0 16.0 26.8 5.4 12.8 11.7 20.2 6.2 19.6 16.7 38.6 58.7 11.7 8.8 6.5 12.1 11.8 13.8 10.8 18.6 9.1 3.6 17.7 13.7 7.8 1.3 19.0 18.2 52.0 19.9 43.7 15.6 50.2 16.2 13.6 9.1 18.9 24.2 12.0 24.9 8.4 14.5 37.3 7.2 6.0 11.3 6.2 55.2 52.6 25.9 6.7 123.0 131.9 6.5 11.0 19.7 15.0 20.5 3.3 11.7 14.6 18.8 7.9 12.9 29.0 36.9 11.3 PDP1 "PDH, PDP, PPM2A, PPM2C" ENSG00000164951 "Pyruvate dehyrogenase phosphatase catalytic subunit 1" Q9P0J1 8 93857807-93926068 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 80.0;Early spermatids: 144.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 8 "amygdala: 14.2;basal ganglia: 20.1;cerebral cortex: 41.7;hippocampal formation: 23.4;white matter: 18.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 117.8;hTERT-RPE1: 117.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018483, HPA019081, HPA021152" Uncertain Approved Nucleoplasm,Mitochondria,Cytosol Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria, Cytosol" "HPA018483: AB_1855634, HPA019081: AB_1855633, HPA021152: AB_1855635" "prognostic unfavorable (8.61e-5)" "unprognostic (4.62e-1)" "unprognostic (8.79e-2)" "unprognostic (1.09e-1)" "unprognostic (9.46e-2)" "unprognostic (1.38e-1)" "unprognostic (1.59e-1)" "unprognostic (1.18e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.71e-2)" "unprognostic (3.25e-1)" "prognostic favorable (8.42e-9)" "unprognostic (1.85e-1)" "unprognostic (1.84e-1)" "unprognostic (5.04e-2)" "unprognostic (1.67e-1)" 10.6 62.6 14.2 10.5 20.1 14.4 16.1 0.0 41.7 14.2 1.2 8.9 7.2 15.5 17.0 14.2 12.2 19.4 49.2 23.4 0.0 12.8 4.2 12.6 12.9 0.0 2.3 19.3 19.9 29.9 5.4 13.8 0.0 10.3 12.4 14.1 11.7 9.4 72.9 4.3 7.6 11.2 0.0 13.2 11.7 26.7 3.0 11.6 18.8 16.9 12.4 14.0 6.8 18.5 25.7 12.0 25.9 10.9 21.0 37.9 8.6 19.3 21.7 22.1 25.8 12.7 90.3 13.9 63.8 30.8 117.8 54.4 11.0 16.1 32.8 1.5 5.6 6.6 15.7 4.5 23.9 3.3 9.0 24.5 31.5 37.7 59.8 117.1 50.9 12.4 2.4 22.8 27.6 6.0 20.3 10.3 12.1 26.8 15.4 4.8 15.5 2.6 15.3 17.0 2.4 11.4 12.7 1.4 61.8 20.9 4.0 3.9 90.9 27.5 17.2 63.8 23.3 12.6 5.8 12.1 34.2 11.7 25.1 6.4 27.9 14.5 9.2 25.3 8.9 15.6 15.1 12.0 22.5 17.9 8.9 7.8 3.1 5.4 41.1 3.7 34.9 18.0 14.2 20.1 0.0 41.7 23.4 0.0 0.0 2.3 0.0 0.0 3.0 18.5 10.7 12.8 7.8 15.0 18.0 13.0 12.7 36.3 68.9 38.3 11.6 7.0 80.0 14.3 35.6 16.5 8.4 4.3 13.7 27.5 5.9 33.3 144.2 33.3 14.9 15.0 10.2 1.3 73.6 14.0 3.9 20.8 16.3 70.2 6.3 3.7 12.5 3.3 6.3 10.1 23.4 5.5 10.2 19.2 19.1 28.1 11.5 19.9 10.6 19.7 22.4 18.8 10.3 13.0 8.5 24.5 9.6 13.5 8.1 15.6 4.9 11.4 30.5 11.5 6.6 35.4 13.1 10.1 11.4 26.5 10.9 4.4 19.3 7.1 10.7 23.9 PDZK1 "NHERF3, PDZD1" ENSG00000174827 "PDZ domain containing 1" Q5T2W1 1 145670852-145708148 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 595.8" "Group enriched" "Detected in many" 5 "Proximal enterocytes: 280.0;Proximal tubular cells: 1113.8" "Group enriched" "Detected in many" 4 "liver cancer: 27.6;renal cancer: 44.3" "Region enriched" "Detected in many" 7 "cerebellum: 14.7" "Immune cell enriched" "Detected in single" 5 "NK-cell: 4.2" "Lineage enriched" "Detected in single" 5 "NK-cells: 4.2" "Group enriched" "Detected in many" 4 "RPTEC TERT1: 250.0;T-47d: 653.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA005755, HPA006155, CAB008971" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Vesicles" Cytosol "CAB008971: , HPA005755: AB_1855164, HPA006155: AB_1855163" "unprognostic (4.56e-3)" "unprognostic (3.07e-1)" "unprognostic (8.79e-2)" "unprognostic (4.41e-2)" "unprognostic (9.15e-2)" "unprognostic (2.09e-1)" "unprognostic (2.18e-1)" "unprognostic (3.42e-1)" "unprognostic (2.08e-1)" "unprognostic (3.27e-1)" "unprognostic (2.34e-2)" "unprognostic (9.87e-3)" "prognostic favorable (2.54e-7)" "unprognostic (9.90e-2)" "unprognostic (3.02e-1)" "unprognostic (1.00e-3)" "unprognostic (8.87e-2)" 0.6 3.5 0.7 0.5 0.9 0.6 19.6 14.7 2.0 2.4 1.9 4.7 74.8 0.7 15.8 0.2 1.0 22.0 0.4 1.0 0.5 595.8 128.1 0.3 0.7 1.4 0.8 0.3 16.6 0.0 0.6 0.5 1.8 0.3 8.2 3.0 0.4 0.8 0.3 2.6 124.9 0.8 0.4 0.7 2.8 0.6 0.8 0.3 0.3 0.1 0.2 0.2 0.3 1.5 7.6 1.2 0.8 0.8 0.3 0.4 3.0 1.2 0.3 0.2 1.0 106.6 1.0 0.7 1.3 5.9 0.5 3.4 0.2 0.6 0.6 10.3 2.0 0.9 2.8 45.7 0.0 1.1 0.9 0.3 0.7 0.4 0.2 0.8 0.0 0.4 0.8 1.6 0.8 6.0 0.7 1.4 1.2 1.5 3.6 0.4 7.3 1.6 250.0 0.3 0.6 6.7 1.7 1.8 0.2 6.4 653.8 0.9 0.5 1.3 1.3 0.9 1.1 8.8 1.2 0.6 1.0 0.6 0.5 0.1 0.1 0.0 0.7 0.1 0.2 0.6 0.2 0.8 0.0 0.4 0.2 0.3 0.1 4.2 0.0 0.5 0.0 0.3 0.7 0.9 14.7 2.0 1.0 0.5 1.4 0.8 1.8 0.4 0.8 1.5 0.2 0.0 0.0 2.0 4.1 0.1 0.0 0.1 0.0 0.4 20.2 3.3 0.5 72.9 0.0 57.0 0.0 0.0 0.9 27.4 138.9 1.2 8.6 1.1 0.5 0.4 6.6 0.0 2.8 2.0 0.1 0.5 0.5 4.9 0.0 0.2 1.1 47.9 0.2 0.0 1.9 7.8 0.0 0.9 0.3 9.0 0.0 4.9 0.0 1.9 0.0 0.3 2.1 3.0 0.7 1.5 7.4 0.0 0.0 0.1 280.0 1113.8 0.1 0.5 0.0 0.1 0.3 0.2 0.3 0.0 0.0 0.1 4.1 4.3 6.5 0.1 PEA15 "HMAT1, HUMMAT1H, MAT1, MAT1H, PEA-15, PED, PED-PEA15, PED/PEA15" ENSG00000162734 "Proliferation and apoptosis adaptor protein 15" Q15121 1 160205380-160215376 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1106.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 246.3;monocytes: 267.6;Muller glia cells: 315.8" "Cancer enhanced" "Detected in all" "glioma: 466.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 78.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028356, HPA070820" Enhanced Supported Nucleoplasm,Cytosol NA NA 300000 "Cluster 7: Monocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" Cytosol Nucleoplasm "HPA028356: AB_10602814, HPA070820: AB_2732166" "unprognostic (1.29e-1)" "unprognostic (4.78e-2)" "unprognostic (1.05e-1)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (1.64e-2)" "unprognostic (1.99e-3)" "unprognostic (6.10e-2)" "unprognostic (4.57e-1)" "unprognostic (1.25e-1)" "unprognostic (6.31e-2)" "unprognostic (4.07e-2)" "prognostic unfavorable (6.53e-7)" "unprognostic (2.60e-2)" "unprognostic (1.39e-1)" "unprognostic (2.82e-3)" "unprognostic (1.24e-1)" 190.2 82.2 863.3 121.7 900.6 16.6 142.7 908.1 949.4 110.1 612.5 146.5 31.7 124.5 83.4 119.2 104.2 88.2 241.9 884.6 939.2 112.0 41.2 147.9 75.5 1028.2 1010.2 80.4 39.6 85.4 80.0 102.3 981.5 112.2 58.5 461.4 80.8 119.4 61.1 105.6 64.8 194.6 933.0 103.2 75.8 80.5 915.2 40.7 83.5 84.5 96.9 133.4 110.2 1106.4 139.2 46.8 190.5 82.5 344.5 191.5 63.6 593.2 503.3 471.6 328.5 103.7 72.3 63.4 210.9 729.4 226.6 146.4 71.5 181.7 365.3 34.4 40.2 52.4 32.5 26.7 423.9 17.8 62.0 161.8 100.7 260.2 328.5 259.6 360.7 45.7 55.1 111.8 640.6 68.3 21.0 41.1 127.0 160.9 134.3 34.4 200.6 43.8 173.0 71.0 38.0 100.0 310.4 207.6 179.9 409.4 128.1 122.6 487.7 311.3 246.4 234.4 254.5 88.1 59.5 118.7 287.1 33.2 450.8 1.3 39.3 5.2 8.4 78.2 6.5 18.9 6.2 6.9 56.7 13.5 3.8 4.2 1.8 7.9 38.7 25.0 7.9 14.9 863.3 900.6 908.1 949.4 884.6 939.2 1028.2 1010.2 981.5 933.0 915.2 1106.4 137.8 16.0 29.9 40.5 38.6 80.2 124.2 21.8 33.6 172.1 76.9 60.2 246.3 11.5 24.7 5.5 73.0 21.8 13.7 12.7 29.4 74.7 65.4 36.4 33.7 125.1 12.0 7.4 24.8 46.3 61.1 81.5 17.9 85.9 31.1 17.2 89.3 6.5 63.3 92.5 19.1 12.0 8.2 42.6 234.6 55.4 66.8 68.9 74.7 14.0 267.6 315.8 8.2 12.1 48.3 102.5 4.7 109.9 14.8 119.4 5.4 18.3 13.8 129.2 46.0 69.4 78.3 16.5 4.1 42.7 73.3 45.3 19.4 18.5 12.8 178.8 PECAM1 CD31 ENSG00000261371 "Platelet and endothelial cell adhesion molecule 1" P16284 17 64319415-64413776 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 455.1" "Cell type enhanced" "Detected in many" "Adipocytes: 672.9;Endothelial cells: 468.2;Hepatic stellate cells: 275.3;Macrophages: 143.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 702.3" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "HUVEC TERT2: 773.0;TIME: 537.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004690, HPA004871" Enhanced Approved "Nucleoli,Plasma membrane" NA NA 110000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoli "HPA004690: AB_1078462, HPA004871: " "unprognostic (2.79e-1)" "unprognostic (2.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.76e-1)" "unprognostic (1.34e-1)" "unprognostic (4.42e-3)" "unprognostic (2.84e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-1)" "unprognostic (7.25e-2)" "unprognostic (4.53e-2)" "unprognostic (9.68e-2)" "prognostic unfavorable (8.98e-5)" "unprognostic (9.72e-3)" "unprognostic (9.57e-2)" "unprognostic (1.56e-1)" "unprognostic (4.16e-2)" 195.6 21.4 20.3 78.9 21.4 35.5 128.5 21.9 25.3 54.9 21.7 37.9 29.7 51.1 9.2 54.3 45.1 88.6 70.3 18.0 22.2 43.6 22.4 204.9 68.0 24.7 23.1 10.7 21.3 29.9 9.7 455.1 24.1 23.5 37.7 4.0 33.4 24.5 35.7 36.2 39.4 83.5 26.3 94.9 30.9 5.0 28.1 62.4 69.8 97.0 60.4 84.0 35.7 22.2 0.1 0.3 1.3 0.1 1.1 1.5 0.4 0.2 0.3 0.0 0.1 4.7 0.1 4.2 121.1 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 95.0 1.8 2.2 3.7 0.5 0.3 0.3 0.0 0.8 0.2 1.6 773.0 34.1 2.3 57.8 0.1 0.4 33.3 8.1 0.1 0.0 9.1 1.4 15.3 3.8 0.0 0.1 0.4 0.3 1.8 0.0 0.1 0.2 0.0 48.5 537.8 0.8 0.5 0.9 0.2 3.4 6.3 6.8 1.6 6.7 0.1 54.8 263.9 219.2 19.8 419.6 18.9 26.7 2.2 46.6 154.0 32.7 36.3 68.6 392.0 40.3 702.3 88.6 2.1 224.2 20.3 21.4 21.9 25.3 18.0 22.2 24.7 23.1 24.1 26.3 28.1 22.2 672.9 16.0 37.9 0.7 24.4 0.0 0.5 0.0 4.0 0.0 4.8 4.6 23.3 1.5 3.1 9.2 0.0 0.5 50.1 0.0 0.0 0.8 0.9 1.1 1.1 468.2 0.0 17.9 1.2 0.2 4.0 22.0 0.0 1.6 8.8 0.0 275.3 3.0 45.8 0.0 1.2 0.0 0.0 110.4 0.0 1.1 2.5 143.9 0.0 47.8 93.8 0.3 26.8 0.5 1.3 0.1 0.0 1.9 109.1 1.3 0.0 0.5 7.3 1.2 0.0 6.9 15.8 0.1 0.5 1.6 0.0 0.8 21.2 4.3 0.1 1.0 PEX12 ENSG00000108733 "Peroxisomal biogenesis factor 12" O00623 17 35574795-35578863 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 17.2;Spermatocytes: 21.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069386 Enhanced NA NA "Cluster 46: Basophils - DNA binding" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA069386: AB_2686135" "unprognostic (1.45e-1)" "unprognostic (6.06e-2)" "unprognostic (1.59e-1)" "unprognostic (2.49e-1)" "unprognostic (1.72e-1)" "unprognostic (1.17e-1)" "unprognostic (1.98e-1)" "unprognostic (9.04e-2)" "unprognostic (2.59e-1)" "unprognostic (1.69e-1)" "unprognostic (5.55e-2)" "unprognostic (2.64e-2)" "prognostic favorable (3.58e-5)" "unprognostic (2.60e-1)" "unprognostic (1.41e-1)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" 3.9 6.8 6.7 3.6 7.2 1.5 5.5 7.9 9.1 5.3 6.7 3.4 3.6 4.3 10.7 3.4 5.6 3.2 9.1 6.8 7.1 8.2 9.0 3.4 4.8 6.8 6.9 8.2 4.0 7.8 4.7 4.7 6.8 5.7 2.9 4.6 5.5 6.9 10.3 4.2 3.5 3.5 7.3 3.9 3.9 6.8 7.0 3.2 7.7 10.8 4.5 3.7 2.7 8.4 2.8 3.7 5.4 4.4 11.0 9.9 3.9 7.3 8.3 6.0 6.3 3.2 3.0 6.4 11.6 4.1 4.9 7.3 6.6 4.8 5.2 2.3 8.7 4.7 3.8 5.9 12.8 6.7 1.2 9.2 9.2 3.7 10.9 7.7 4.6 5.2 7.5 6.6 7.2 2.9 7.9 3.8 2.2 6.3 5.8 3.8 9.3 6.4 7.1 4.2 4.0 4.0 4.6 3.0 9.6 6.5 7.4 3.7 3.7 5.6 3.5 6.3 4.9 13.3 9.9 7.5 6.0 5.1 5.2 2.2 1.5 3.0 1.8 1.1 3.2 2.3 3.0 1.8 1.7 2.6 4.1 3.5 1.0 2.0 1.2 1.7 2.4 1.4 6.7 7.2 7.9 9.1 6.8 7.1 6.8 6.9 6.8 7.3 7.0 8.4 2.7 3.2 0.5 6.5 3.3 0.6 1.9 1.3 1.8 2.1 2.4 2.2 6.3 0.0 2.7 3.7 0.0 6.7 1.4 1.3 3.9 3.5 17.2 1.9 2.3 3.9 1.2 0.8 1.3 1.1 4.1 2.6 2.6 1.5 2.5 2.0 3.3 5.4 2.9 1.7 1.9 1.7 2.0 2.6 0.6 3.0 3.1 1.5 1.8 1.0 0.9 8.3 1.0 4.5 2.8 2.2 1.0 1.5 0.5 2.4 2.7 3.3 1.8 2.2 0.0 2.6 3.7 21.0 10.2 1.4 1.3 5.2 2.8 3.0 2.2 1.3 PEX19 "D1S2223E, HK33, PMP1, PMPI, PXF, PXMP1" ENSG00000162735 "Peroxisomal biogenesis factor 19" P40855 1 160276807-160286348 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Peroxisome biogenesis" "Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044837, HPA051966" Supported Supported Peroxisomes NA NA 7900 "Cluster 34: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Peroxisomes "HPA044837: AB_10962496, HPA051966: AB_2681677" "unprognostic (1.49e-2)" "unprognostic (2.26e-1)" "unprognostic (3.42e-1)" "unprognostic (4.80e-3)" "unprognostic (3.89e-2)" "unprognostic (3.88e-2)" "unprognostic (3.79e-1)" "unprognostic (1.51e-1)" "unprognostic (2.32e-1)" "unprognostic (1.53e-2)" "unprognostic (8.06e-2)" "unprognostic (1.00e-1)" "prognostic favorable (2.92e-5)" "unprognostic (3.46e-2)" "unprognostic (2.25e-1)" "unprognostic (2.19e-2)" "unprognostic (1.24e-2)" 79.3 25.7 21.1 14.5 22.5 12.3 36.5 22.2 23.5 20.3 15.6 22.6 19.4 18.2 25.0 24.9 22.9 19.6 39.4 21.5 22.7 33.1 109.1 21.6 16.6 22.3 23.5 23.6 17.2 40.4 15.0 21.9 23.5 28.0 23.2 30.9 21.3 26.6 66.2 18.2 18.8 16.7 22.1 16.7 20.0 16.8 22.7 21.0 34.3 84.8 20.5 23.9 15.2 24.5 31.2 18.9 69.8 22.4 59.8 57.8 53.0 25.3 51.3 44.6 35.3 35.1 37.2 37.8 40.9 37.3 26.3 29.7 34.2 44.0 35.3 32.3 17.3 26.6 26.5 36.3 46.9 48.6 32.6 84.7 51.0 60.0 38.6 35.8 32.2 51.4 40.8 27.9 50.0 17.8 37.0 15.8 50.3 38.6 48.2 45.7 34.4 45.5 45.8 61.8 23.2 38.3 98.3 49.5 37.4 71.3 48.1 48.2 24.8 26.5 31.1 29.9 30.1 42.5 57.9 68.6 43.1 20.9 38.9 9.1 5.5 5.0 5.8 8.9 4.2 5.0 2.8 3.5 5.5 1.9 4.0 3.7 2.2 4.7 6.6 3.4 4.2 2.3 21.1 22.5 22.2 23.5 21.5 22.7 22.3 23.5 23.5 22.1 22.7 24.5 16.4 9.6 20.6 9.1 12.7 9.9 21.0 15.4 13.1 18.8 18.9 16.4 45.6 20.0 11.3 16.5 10.4 30.0 6.9 25.4 49.0 22.6 6.6 12.0 13.7 13.6 11.4 15.6 8.6 14.8 51.2 18.4 13.3 12.0 16.5 15.6 20.0 60.1 30.1 25.2 9.0 11.5 0.0 15.7 7.0 3.1 21.8 15.0 21.4 6.5 24.9 39.0 12.3 6.0 11.5 20.2 17.2 29.3 9.5 18.5 29.8 40.7 11.8 12.7 32.9 14.6 16.2 17.8 25.3 15.0 9.9 38.7 12.5 18.2 15.7 25.2 PEX3 ENSG00000034693 "Peroxisomal biogenesis factor 3" P56589 6 143450805-143490616 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Peroxisome biogenesis" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 80.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042830, HPA058006" Supported Approved Nucleoplasm,Peroxisomes NA NA "Cluster 44: Non-specific - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Peroxisomes" "HPA042830: AB_10794918, HPA058006: AB_2683576" "unprognostic (3.52e-3)" "unprognostic (6.28e-2)" "unprognostic (1.81e-2)" "unprognostic (1.51e-2)" "unprognostic (1.21e-1)" "unprognostic (4.16e-1)" "unprognostic (8.45e-2)" "unprognostic (1.19e-1)" "unprognostic (1.09e-1)" "unprognostic (1.56e-2)" "unprognostic (2.50e-2)" "unprognostic (2.16e-1)" "prognostic favorable (3.80e-4)" "unprognostic (1.87e-1)" "unprognostic (7.30e-2)" "unprognostic (3.80e-2)" "unprognostic (2.12e-1)" 8.7 38.4 4.4 7.6 4.8 3.2 11.8 4.5 5.6 11.7 7.3 7.5 6.0 9.8 12.5 17.8 9.6 7.3 12.6 4.2 5.3 18.3 24.4 7.9 8.8 3.6 3.4 10.7 6.7 24.4 9.0 9.4 3.9 11.7 6.2 10.0 10.6 11.2 11.6 12.8 7.4 8.9 3.9 7.2 9.7 12.2 3.6 8.3 15.5 9.6 9.5 8.9 13.4 7.5 21.4 4.6 11.0 21.1 17.8 15.6 12.2 17.8 13.8 23.7 28.3 31.5 12.8 31.7 21.1 17.4 27.8 17.3 14.4 23.9 30.8 19.4 16.5 22.8 10.2 20.0 15.0 38.7 9.6 18.1 16.6 22.4 17.2 10.3 13.0 18.5 21.1 15.7 24.0 14.1 20.2 15.3 6.1 12.6 18.2 15.3 22.2 14.0 28.0 9.2 15.3 5.3 23.0 19.3 14.7 9.5 10.2 12.7 10.3 16.7 15.9 26.9 20.9 10.7 16.4 36.1 21.1 26.0 13.3 12.9 6.3 6.4 15.5 10.1 17.2 23.2 16.3 15.5 9.9 18.6 21.1 20.7 1.0 15.6 13.4 10.6 21.2 9.8 4.4 4.8 4.5 5.6 4.2 5.3 3.6 3.4 3.9 3.9 3.6 7.5 13.1 16.0 14.4 23.8 19.7 26.6 12.7 19.2 14.8 14.5 9.9 11.8 14.8 5.7 19.0 9.2 4.2 41.7 9.0 4.1 19.6 12.3 12.6 15.2 10.4 12.0 6.0 5.9 61.0 9.5 11.6 13.5 10.2 13.1 25.3 9.6 13.6 20.5 11.5 16.8 67.4 5.4 16.2 7.6 6.6 4.9 13.7 6.0 8.8 28.1 8.0 15.4 10.3 40.7 59.6 9.6 2.3 11.3 18.1 6.6 8.2 28.8 27.2 12.1 6.6 12.2 13.6 80.0 18.5 20.2 34.8 58.7 13.7 20.9 7.6 8.5 PGAP3 "CAB2, MGC9753, PER1, PERLD1, PP1498" ENSG00000161395 "Post-GPI attachment to proteins phospholipase 3" Q96FM1 17 39671122-39696797 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 6 "OE19: 800.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016591 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "HPA016591: AB_1855203" "unprognostic (1.29e-1)" "unprognostic (8.64e-2)" "unprognostic (1.65e-1)" "unprognostic (6.53e-3)" "unprognostic (9.19e-2)" "unprognostic (1.68e-2)" "prognostic favorable (3.94e-4)" "unprognostic (1.61e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (6.82e-4)" "unprognostic (1.57e-2)" "unprognostic (7.79e-2)" "prognostic favorable (3.89e-4)" "unprognostic (5.16e-2)" "unprognostic (1.31e-1)" "unprognostic (9.05e-2)" "unprognostic (1.94e-2)" 10.5 11.9 17.0 5.6 17.2 5.0 12.9 14.0 19.6 14.6 16.2 18.6 14.9 11.3 18.3 25.8 15.9 13.4 14.8 17.5 16.7 20.6 35.6 12.1 7.4 14.9 15.4 13.5 27.1 22.7 14.9 11.8 14.6 18.5 13.7 7.1 25.1 11.7 8.3 21.0 17.1 6.1 14.7 12.3 16.6 9.1 16.5 4.8 27.1 4.5 7.5 12.2 13.7 15.5 3.7 9.6 7.7 7.0 7.9 8.1 7.9 4.3 10.1 6.7 6.1 5.4 23.8 4.2 19.7 8.3 2.2 12.6 2.4 2.9 3.1 8.6 7.7 5.2 6.0 9.3 10.6 12.9 12.8 14.9 15.0 3.1 6.8 7.6 2.2 1.9 4.9 9.6 6.1 8.7 2.9 11.7 7.6 800.4 2.1 3.2 4.7 12.1 10.7 12.0 7.1 4.7 11.9 134.0 6.9 0.8 11.4 12.4 3.4 7.2 7.6 3.5 3.3 8.5 2.0 1.4 8.1 4.9 8.1 2.6 7.2 4.6 15.2 11.6 8.3 8.1 10.6 12.5 5.7 7.7 10.1 10.1 2.0 10.4 4.3 3.9 5.4 7.3 17.0 17.2 14.0 19.6 17.5 16.7 14.9 15.4 14.6 14.7 16.5 15.5 6.5 3.2 14.9 7.8 3.7 3.8 3.3 5.6 3.4 12.6 9.1 7.0 7.7 14.3 10.1 14.7 8.4 8.1 5.3 20.3 1.9 7.6 0.1 3.5 4.5 5.0 8.4 3.0 9.0 11.1 6.5 5.1 9.2 5.7 8.9 6.8 4.6 9.0 4.4 13.5 6.3 15.3 8.2 5.1 2.8 0.1 3.1 3.7 1.8 2.8 1.9 7.5 4.1 9.0 6.1 6.3 13.9 1.5 2.8 3.7 22.9 3.4 4.9 22.1 0.0 5.0 3.3 0.7 2.4 8.1 2.8 10.4 4.9 5.8 13.3 3.1 PGM2L1 "BM32A, FLJ32029" ENSG00000165434 "Phosphoglucomutase 2 like 1" Q6PCE3 11 74330316-74398433 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Isomerase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 90.1;Exocrine glandular cells: 124.5;Pancreatic endocrine cells: 140.1;Respiratory ciliated cells: 95.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 16.6;LHCN-M2: 19.9;RH-30: 18.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056995, HPA060948" Enhanced Approved Mitochondria No No 140000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 1: Pancreatic cells - Digestion" Mitochondria "HPA056995: AB_2683305, HPA060948: AB_2684394" "unprognostic (7.44e-3)" "unprognostic (1.33e-1)" "unprognostic (7.28e-3)" "unprognostic (8.91e-2)" "unprognostic (6.16e-2)" "unprognostic (1.55e-1)" "unprognostic (7.16e-6)" "unprognostic (1.43e-1)" "unprognostic (1.95e-1)" "unprognostic (5.97e-3)" "unprognostic (1.70e-2)" "unprognostic (2.98e-1)" "unprognostic (9.33e-3)" "unprognostic (3.71e-1)" "unprognostic (1.97e-1)" "unprognostic (3.04e-1)" "unprognostic (1.03e-2)" 1.9 2.6 17.6 3.7 22.1 3.2 1.9 0.0 21.5 4.9 0.0 3.2 1.3 4.4 0.8 1.0 3.2 3.3 1.1 23.1 16.2 1.6 1.0 1.8 3.0 1.9 4.5 0.9 3.1 0.7 3.9 1.1 2.2 2.9 3.5 2.6 2.6 1.3 5.9 0.7 1.5 4.0 0.3 1.5 2.1 1.3 5.7 8.1 2.7 11.1 2.7 6.4 1.9 7.8 2.7 3.8 14.5 2.7 4.3 1.9 0.4 3.5 2.6 3.0 3.3 1.4 6.8 0.3 8.5 2.3 5.3 1.3 2.9 0.7 2.8 1.1 1.5 2.1 2.0 1.1 0.5 2.4 3.2 1.0 0.7 6.8 1.2 3.2 16.6 5.0 2.8 1.8 19.9 0.3 9.9 2.1 2.9 2.0 3.3 3.1 18.9 0.1 7.8 0.5 0.7 2.9 5.7 1.3 2.6 3.9 0.2 0.4 14.0 6.6 6.0 2.7 3.7 2.4 3.8 0.3 0.6 3.4 1.6 1.2 0.3 0.5 0.9 0.3 1.3 1.1 1.6 1.1 0.2 0.8 1.5 0.8 0.3 1.4 0.2 0.8 3.9 0.5 17.6 22.1 0.0 21.5 23.1 16.2 1.9 4.5 2.2 0.3 5.7 7.8 19.6 6.4 6.4 8.5 20.9 7.6 41.2 14.3 10.8 23.9 26.5 19.4 7.3 17.2 30.2 9.2 16.7 0.6 17.6 13.8 5.9 37.4 14.1 28.1 23.5 32.1 11.9 47.5 90.1 124.5 5.3 21.0 7.1 25.5 8.2 16.1 29.3 1.0 5.4 8.4 64.8 16.2 18.3 23.0 21.6 3.6 2.5 9.9 16.0 20.6 4.6 4.4 12.3 14.6 7.1 140.1 9.3 3.8 13.4 50.4 4.2 5.3 95.4 11.0 26.3 21.3 16.7 34.2 21.2 9.0 5.3 0.1 25.0 8.8 20.9 55.6 PGM5 PGMRP ENSG00000154330 "Phosphoglucomutase 5" Q15124 9 68328308-68531061 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Cell adhesion, Glucose metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 269.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 107.2;Endothelial cells: 36.6;Hepatic stellate cells: 39.3;Microglial cells: 124.6;Sertoli cells: 52.6;Smooth muscle cells: 35.9" "Cancer enhanced" "Detected in many" "prostate cancer: 16.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 48 "neutrophil: 4.8" "Lineage enriched" "Detected in single" 48 "granulocytes: 4.8" "Group enriched" "Detected in some" 5 "hTERT-RPE1: 28.7;PC-3: 56.5;RH-30: 38.8;SK-BR-3: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034397, HPA046329, HPA067102" Enhanced Uncertain Cytosol NA NA 450000 "Cluster 1: Neutrophils - Mixed function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB034397: AB_1118633, HPA046329: AB_2679625, HPA067102: AB_2732758" "unprognostic (3.43e-1)" "unprognostic (2.17e-2)" "unprognostic (3.98e-3)" "unprognostic (5.75e-2)" "unprognostic (1.10e-1)" "unprognostic (1.09e-1)" "unprognostic (3.15e-4)" "unprognostic (1.22e-3)" "unprognostic (2.79e-1)" "unprognostic (5.28e-3)" "unprognostic (4.78e-2)" "unprognostic (2.28e-2)" "prognostic favorable (1.83e-5)" "unprognostic (3.04e-2)" "unprognostic (2.91e-1)" "unprognostic (2.48e-1)" "unprognostic (4.73e-2)" 28.9 61.0 3.7 12.6 4.1 0.0 21.0 5.8 3.8 51.7 3.3 269.4 15.4 154.0 40.8 98.6 96.5 19.6 126.1 3.1 4.1 11.5 5.1 14.6 5.8 4.6 4.0 19.8 2.7 5.0 4.3 5.8 4.3 159.0 34.2 8.0 6.7 214.0 37.5 11.1 72.0 132.5 4.7 10.8 65.2 3.0 4.6 2.9 13.1 30.5 2.9 216.7 40.6 4.6 0.2 0.2 0.0 0.0 0.7 0.0 0.3 8.2 6.3 3.8 1.7 0.0 0.0 0.2 0.0 0.0 0.1 0.1 9.2 0.0 9.4 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.0 28.7 0.0 0.0 0.0 0.1 0.0 4.1 0.1 0.7 0.0 0.0 56.5 0.0 38.8 1.8 1.5 0.0 0.0 0.2 0.1 47.8 2.8 1.2 0.0 0.0 0.1 0.0 5.7 0.3 0.3 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 3.7 4.1 5.8 3.8 3.1 4.1 4.6 4.0 4.3 4.7 4.6 4.6 21.6 0.0 1.7 0.7 0.2 2.3 5.6 0.0 0.6 25.3 0.2 1.5 107.2 2.8 1.8 12.9 4.2 0.0 0.1 0.1 1.9 0.1 1.8 3.7 2.8 36.6 0.0 4.0 1.4 0.0 0.2 12.4 0.0 1.1 0.0 18.7 39.3 0.1 0.1 0.0 1.7 2.7 0.0 4.0 2.8 0.5 8.1 2.1 3.6 124.6 1.0 8.3 0.0 1.0 2.3 0.1 0.1 4.9 0.0 2.1 0.8 1.2 0.8 1.9 52.6 1.7 35.9 0.1 0.2 0.4 2.4 0.0 0.6 30.0 1.6 1.5 PGRMC1 HPR6.6 ENSG00000101856 "Progesterone receptor membrane component 1" O00264 X 119236245-119244466 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 677.4" "Cell type enhanced" "Detected in all" "Hepatocytes: 520.4;Theca cells: 907.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002877, HPA064724" Enhanced Supported "Nucleoli,Endoplasmic reticulum" NA NA 1200000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 5: NTERA-2 - Transcription" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum" Nucleoli "HPA002877: AB_1079602, HPA064724: " "unprognostic (6.97e-2)" "unprognostic (1.99e-1)" "unprognostic (1.72e-1)" "unprognostic (4.35e-1)" "unprognostic (6.51e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (1.58e-3)" "unprognostic (9.28e-2)" "unprognostic (4.66e-2)" "unprognostic (6.20e-2)" "unprognostic (3.08e-2)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (3.06e-3)" "unprognostic (2.08e-1)" "unprognostic (1.01e-1)" "unprognostic (1.11e-1)" 108.0 171.3 97.9 37.5 102.5 25.1 106.0 83.8 115.5 135.4 96.3 98.2 109.3 154.5 273.3 57.0 149.0 56.9 38.6 102.3 127.0 235.4 677.4 62.1 27.6 97.2 109.3 93.3 40.2 113.9 59.1 44.9 126.1 127.6 87.3 80.5 71.4 200.4 15.7 53.2 131.9 85.2 106.1 41.4 77.1 46.5 112.8 33.4 89.0 27.0 29.3 77.3 65.0 116.9 165.6 102.4 196.3 227.7 414.2 196.9 127.1 243.0 281.0 126.1 155.7 124.5 196.6 47.3 259.5 253.8 147.3 128.3 216.5 102.1 168.8 50.8 248.7 53.7 88.5 141.0 69.0 88.4 27.5 204.7 56.5 153.8 79.2 93.5 82.6 55.7 57.2 28.8 150.3 176.5 66.9 64.7 515.8 179.4 170.3 78.5 123.1 68.5 168.7 123.9 182.9 81.7 178.1 291.7 98.9 188.2 67.4 56.2 64.2 87.6 127.7 312.6 233.6 29.9 59.2 51.0 238.8 138.6 170.6 21.0 20.1 20.4 8.7 19.9 11.8 5.8 12.0 12.9 17.0 5.5 12.0 10.1 9.1 8.8 18.4 12.0 13.4 50.2 97.9 102.5 83.8 115.5 102.3 127.0 97.2 109.3 126.1 106.1 112.8 116.9 109.1 125.0 91.4 16.0 19.0 94.1 131.3 67.4 81.4 199.1 110.8 95.1 17.1 120.1 76.7 73.5 68.8 88.2 25.8 170.5 68.4 93.0 4.2 119.7 264.2 81.9 57.7 37.6 36.5 73.0 138.6 153.1 50.4 122.4 40.5 197.0 66.4 520.4 51.8 65.6 58.5 85.0 81.4 35.0 51.2 9.0 172.1 111.1 103.2 15.0 26.5 109.8 18.6 108.6 91.3 68.9 144.7 181.7 22.6 118.8 375.5 295.1 105.4 92.4 105.2 99.2 111.1 68.2 77.2 69.3 87.7 62.1 32.1 907.9 137.6 127.9 PHACTR3 "C20orf101, PPP1R123" ENSG00000087495 "Phosphatase and actin regulator 3" Q96KR7 20 59577509-59847711 "Predicted intracellular proteins" "Actin-binding, Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 104.4;choroid plexus: 36.5" "Cell type enhanced" "Detected in many" "Astrocytes: 205.7;Excitatory neurons: 100.4;Inhibitory neurons: 88.7;Oligodendrocyte precursor cells: 218.1;Oligodendrocytes: 241.1" "Group enriched" "Detected in some" 5 "glioma: 3.8;lung cancer: 1.6;pancreatic cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 85.4;HBEC3-KT: 64.6;PC-3: 113.2;THP-1: 131.3;U-937: 32.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051834, HPA054847" Enhanced Nucleoplasm NA NA "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA051834: AB_2681629, HPA054847: " "unprognostic (7.14e-2)" "unprognostic (1.22e-1)" "unprognostic (3.72e-2)" "unprognostic (1.43e-7)" "unprognostic (1.99e-1)" "unprognostic (2.87e-2)" "unprognostic (5.83e-3)" "unprognostic (8.92e-2)" "unprognostic (5.02e-2)" "unprognostic (2.30e-2)" "unprognostic (7.71e-2)" "unprognostic (7.22e-2)" "unprognostic (1.74e-2)" "unprognostic (1.66e-1)" "unprognostic (5.43e-2)" "unprognostic (2.53e-3)" "unprognostic (1.32e-1)" 0.9 1.2 90.4 0.5 92.4 0.5 0.4 82.0 93.4 0.3 36.5 0.8 0.7 1.0 0.7 1.1 8.6 1.9 4.0 82.3 75.4 2.2 0.6 5.9 0.1 78.5 82.4 6.2 0.2 0.0 1.7 0.6 76.1 0.1 0.8 3.3 0.1 0.0 0.2 1.1 1.0 0.3 74.7 5.5 0.5 0.5 93.7 1.9 0.1 1.0 0.1 0.5 0.1 104.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 85.4 0.0 6.2 1.3 0.0 0.2 0.3 64.6 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 1.4 0.1 10.5 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 17.9 0.3 0.4 113.2 0.0 0.0 0.7 25.1 1.4 2.1 6.5 0.5 0.0 0.1 0.0 0.5 131.3 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 90.4 92.4 82.0 93.4 82.3 75.4 78.5 82.4 76.1 74.7 93.7 104.4 0.3 12.8 0.5 205.7 0.3 0.6 1.3 2.1 0.0 13.8 0.2 0.0 8.9 10.0 8.4 3.7 0.0 0.0 0.0 0.0 1.9 1.1 1.0 7.1 3.7 0.3 1.2 0.0 100.4 0.0 0.0 4.2 0.0 2.1 0.0 0.5 3.3 0.0 0.2 5.0 88.7 0.9 44.7 0.3 1.1 0.9 0.0 3.7 0.0 7.5 0.0 0.8 0.0 218.1 241.1 2.9 0.1 0.0 0.9 2.9 4.3 0.1 1.3 1.9 0.0 2.9 0.9 0.3 1.0 0.1 0.4 0.0 0.1 0.9 4.5 3.2 PHETA2 "DKFZp686J07229, FAM109B, IPIP27B, SES2" ENSG00000177096 "PH domain containing endocytic trafficking adaptor 2" Q6ICB4 22 42074248-42079438 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 14.1;Endometrial stromal cells: 10.3;Extravillous trophoblasts: 27.4;Syncytiotrophoblasts: 22.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 20.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 36.8;fHDF/TERT166: 33.7;HSkMC: 32.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA000647 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA000647: AB_1078800" "unprognostic (4.96e-2)" "unprognostic (3.28e-2)" "unprognostic (5.90e-2)" "unprognostic (6.66e-3)" "unprognostic (1.56e-2)" "unprognostic (9.61e-3)" "unprognostic (2.40e-1)" "unprognostic (1.19e-1)" "unprognostic (2.31e-1)" "unprognostic (2.84e-1)" "unprognostic (1.07e-1)" "unprognostic (8.80e-2)" "unprognostic (7.52e-2)" "unprognostic (1.78e-1)" "unprognostic (1.15e-2)" "unprognostic (2.81e-2)" "unprognostic (4.03e-2)" 11.1 4.3 2.8 6.6 2.7 4.6 9.7 2.5 2.8 12.2 4.3 11.4 6.0 15.4 2.8 9.6 9.8 8.2 8.5 2.5 2.8 7.1 1.9 9.7 4.1 3.1 2.7 5.2 18.2 4.8 5.8 15.6 2.8 9.9 8.5 0.4 12.7 7.6 2.5 8.3 9.4 12.9 3.1 7.8 13.4 2.5 2.8 2.4 5.8 3.1 4.2 11.3 9.1 2.8 0.1 0.0 0.0 0.2 30.9 36.8 0.2 21.4 17.5 13.0 12.9 22.6 20.5 0.1 13.1 33.7 0.0 3.7 0.1 0.2 6.9 0.0 0.0 0.0 29.1 0.2 17.6 0.0 17.1 32.3 9.5 20.1 2.5 0.0 29.3 0.3 0.2 0.0 14.1 0.4 0.1 0.2 2.4 1.1 0.0 0.2 0.1 0.3 5.9 0.0 0.2 0.2 9.2 0.1 0.1 0.2 14.1 0.0 30.0 0.2 13.8 31.5 0.1 0.5 0.5 0.3 0.0 0.4 24.0 20.0 4.3 1.7 1.3 4.9 0.2 0.5 0.8 1.0 8.4 0.2 0.6 1.2 0.3 0.7 2.8 3.9 0.6 3.2 2.8 2.7 2.5 2.8 2.5 2.8 3.1 2.7 2.8 3.1 2.8 2.8 4.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.8 2.4 0.0 0.0 0.0 0.0 0.0 14.1 0.2 0.0 3.9 5.7 0.0 1.1 10.3 3.0 0.0 0.0 0.0 7.0 27.4 6.6 0.0 2.8 0.0 3.8 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 2.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 22.2 0.2 3.6 0.0 0.0 PIGP "DCRC, DSCR5, DSRC" ENSG00000185808 "Phosphatidylinositol glycan anchor biosynthesis class P" P57054 21 37062846-37073170 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 350.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026921 Uncertain Approved Vesicles Yes No "Cluster 30: Non-specific - Translation" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "HPA026921: AB_1847874" "unprognostic (4.47e-3)" "unprognostic (9.45e-2)" "unprognostic (3.03e-1)" "unprognostic (2.40e-1)" "unprognostic (2.85e-2)" "unprognostic (1.92e-2)" "unprognostic (1.92e-2)" "unprognostic (5.54e-2)" "unprognostic (1.55e-1)" "unprognostic (1.22e-2)" "unprognostic (4.21e-3)" "unprognostic (1.12e-2)" "unprognostic (1.96e-2)" "unprognostic (1.93e-1)" "unprognostic (5.48e-2)" "unprognostic (1.02e-1)" "unprognostic (6.55e-2)" 33.9 41.3 18.7 12.5 20.2 9.1 35.4 22.4 24.7 22.9 24.8 24.2 19.0 18.3 107.2 16.8 25.7 22.5 40.1 18.1 22.8 35.9 54.7 21.6 16.6 22.8 21.6 27.9 41.4 51.9 38.0 20.9 22.6 33.7 27.4 28.6 32.2 26.7 44.0 12.4 15.5 17.1 22.1 14.9 22.8 36.5 20.0 22.0 36.3 42.8 19.7 26.2 13.2 25.4 25.9 11.5 23.7 14.8 41.5 28.6 16.9 21.9 38.7 18.6 21.1 15.4 53.7 37.1 45.7 32.0 81.4 19.4 22.7 25.5 18.5 37.4 36.1 86.2 13.8 21.3 26.3 26.9 16.6 26.5 47.2 33.4 43.0 42.2 35.1 80.5 50.7 61.8 38.5 16.5 32.9 25.5 19.6 76.8 27.9 31.0 12.1 37.0 48.2 13.3 49.2 29.8 61.4 43.0 81.8 33.6 35.2 53.2 18.3 12.9 6.6 14.8 19.3 81.1 96.5 42.0 38.1 30.5 43.4 0.4 13.5 3.7 19.6 20.3 24.8 34.2 25.1 21.6 20.9 28.1 33.3 29.0 1.9 16.8 22.6 30.9 20.6 15.6 18.7 20.2 22.4 24.7 18.1 22.8 22.8 21.6 22.6 22.1 20.0 25.4 37.4 28.9 41.8 9.8 37.0 33.0 58.9 88.9 35.3 21.2 74.1 86.4 82.4 42.9 65.1 44.1 10.4 60.7 29.4 21.6 90.1 61.8 79.3 67.0 35.9 31.3 44.9 25.7 6.9 71.3 52.4 48.9 30.1 49.3 15.9 32.2 35.3 79.8 66.7 16.8 8.7 63.9 65.1 57.6 39.9 75.6 69.0 44.1 37.4 2.8 50.2 37.0 23.7 7.5 18.2 57.7 50.3 35.0 54.3 45.6 52.3 97.1 86.9 33.6 65.7 32.7 44.6 350.8 177.5 44.2 26.3 52.3 31.7 62.6 53.1 63.7 PIGV FLJ20477 ENSG00000060642 "Phosphatidylinositol glycan anchor biosynthesis class V" Q9NUD9 1 26787054-26800659 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 50.8;Late spermatids: 96.0;Spermatocytes: 80.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 43.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054181 Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "Endoplasmic reticulum" "HPA054181: " "unprognostic (2.08e-1)" "unprognostic (6.53e-2)" "unprognostic (1.32e-3)" "unprognostic (1.96e-2)" "unprognostic (2.02e-2)" "unprognostic (5.76e-2)" "unprognostic (2.00e-1)" "unprognostic (1.61e-1)" "unprognostic (1.72e-1)" "unprognostic (1.56e-1)" "unprognostic (8.40e-2)" "unprognostic (4.44e-2)" "prognostic favorable (7.60e-7)" "unprognostic (1.71e-1)" "unprognostic (4.24e-1)" "unprognostic (8.92e-2)" "unprognostic (5.96e-3)" 6.6 13.9 4.6 3.4 5.3 3.0 7.6 5.1 4.8 9.5 4.1 8.1 6.5 8.1 13.8 9.0 10.2 6.2 4.4 4.2 4.7 10.9 24.1 6.2 4.2 6.1 5.2 7.9 10.3 13.9 10.0 6.2 5.5 8.4 8.4 3.7 10.0 8.0 4.4 11.3 7.3 6.7 5.2 6.9 8.9 30.0 5.1 6.7 10.6 4.8 6.4 8.5 8.3 5.4 10.6 4.4 4.1 4.7 7.3 10.8 5.8 6.7 14.0 7.6 7.9 2.3 25.9 6.7 7.3 7.7 8.2 20.3 4.2 8.6 8.6 11.5 2.5 5.6 5.1 5.1 10.3 7.7 10.0 11.8 43.8 9.8 12.2 12.0 5.1 9.4 10.0 12.2 14.0 3.9 3.7 3.0 9.9 20.9 3.0 3.8 6.2 15.0 11.0 1.0 7.6 3.9 9.2 4.3 8.7 9.8 14.1 6.5 8.1 10.8 6.5 6.0 1.8 3.8 2.2 2.9 10.7 10.0 8.2 33.1 14.1 11.0 14.0 13.0 21.1 8.8 9.9 14.4 12.5 8.8 10.2 12.4 14.2 21.5 18.5 4.5 9.7 10.8 4.6 5.3 5.1 4.8 4.2 4.7 6.1 5.2 5.5 5.2 5.1 5.4 5.2 3.2 6.0 7.5 6.0 4.2 11.0 27.5 6.2 3.3 10.0 7.6 1.9 4.3 12.7 7.3 8.4 27.4 10.6 5.0 7.9 7.2 50.8 6.7 4.7 4.6 3.5 13.5 2.8 4.6 14.8 8.8 6.1 6.4 0.0 6.8 6.4 16.6 9.2 8.4 3.2 6.5 12.2 5.2 3.2 96.0 7.2 4.2 7.2 2.8 8.2 11.1 7.2 0.0 5.5 4.9 4.8 9.8 6.5 7.6 12.1 10.2 16.3 2.7 0.0 5.7 4.9 80.8 15.1 7.3 4.1 14.1 8.2 12.1 9.2 8.4 PIK3C2G ENSG00000139144 "Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma" O75747 12 18242961-18648416 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Chemotaxis "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 16.7;stomach 1: 21.7" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 44.9;Breast glandular cells: 30.4;Breast myoepithelial cells: 37.6;Collecting duct cells: 40.5;Gastric mucus-secreting cells: 140.6" "Cancer enhanced" "Detected in some" "stomach cancer: 2.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BEWO: 1.2;HaCaT: 2.1;hTERT-HME1: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (1.29e-1)" "unprognostic (1.61e-1)" "unprognostic (6.21e-2)" "unprognostic (1.47e-2)" "unprognostic (9.46e-2)" "unprognostic (8.27e-2)" "unprognostic (2.85e-1)" "unprognostic (6.52e-2)" "unprognostic (1.81e-3)" "prognostic unfavorable (3.50e-4)" "unprognostic (6.05e-2)" "unprognostic (1.81e-1)" "unprognostic (2.74e-1)" "unprognostic (1.98e-1)" "unprognostic (2.37e-2)" 0.0 0.6 0.4 0.0 0.1 0.1 9.7 0.3 0.4 0.2 0.1 0.1 0.5 0.1 16.7 2.4 1.2 6.3 0.0 0.1 0.7 4.6 12.0 0.3 0.1 0.1 0.2 0.0 1.4 4.8 0.0 0.0 0.1 0.9 0.2 0.1 3.7 9.4 0.0 9.7 3.3 0.0 0.3 0.1 21.7 0.4 0.4 0.1 0.0 0.1 0.1 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 3.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.3 0.4 0.1 0.7 0.1 0.2 0.1 0.3 0.4 0.3 1.1 0.0 0.0 1.3 0.7 17.5 8.5 0.3 44.9 0.0 30.4 37.6 0.3 27.1 0.8 40.5 0.0 1.2 0.4 0.2 1.9 2.0 9.0 4.5 1.5 1.2 0.0 2.7 2.9 0.0 4.8 0.4 140.6 10.1 0.0 0.0 0.7 27.4 0.2 0.0 1.8 2.3 0.0 0.8 1.1 1.8 0.0 0.5 1.8 7.5 0.0 0.0 0.0 1.5 1.4 0.8 5.1 0.0 1.3 0.8 18.4 1.3 0.1 0.0 0.0 0.1 0.5 2.4 3.0 27.3 21.5 0.8 1.0 0.0 3.0 1.6 PINK1 "BRPK, PARK6" ENSG00000158828 "PTEN induced kinase 1" Q9BXM7 1 20633458-20651511 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Autophagy "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 384.4;tongue: 392.3" "Cell type enhanced" "Detected in many" "Late spermatids: 151.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 8.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001931, CAB026191" Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB026191: , HPA001931: AB_1079620" "unprognostic (3.73e-3)" "unprognostic (2.29e-2)" "unprognostic (3.22e-1)" "unprognostic (4.33e-2)" "unprognostic (4.91e-2)" "unprognostic (2.93e-2)" "unprognostic (1.56e-2)" "unprognostic (3.36e-2)" "unprognostic (3.51e-2)" "unprognostic (4.06e-3)" "unprognostic (3.34e-2)" "unprognostic (2.54e-1)" "prognostic favorable (1.11e-16)" "unprognostic (2.68e-1)" "unprognostic (1.62e-1)" "unprognostic (6.57e-2)" "unprognostic (1.08e-1)" 50.7 127.2 119.3 13.7 103.4 13.0 41.9 104.6 110.9 37.9 73.0 62.3 32.3 43.9 18.8 48.8 34.4 23.5 153.4 106.6 107.0 56.8 76.8 30.1 10.8 118.5 127.8 30.1 52.7 66.5 33.4 21.3 118.3 37.1 15.0 29.4 55.0 29.7 384.4 55.3 35.2 20.0 124.9 27.9 46.7 94.8 132.1 12.3 41.6 392.3 8.3 47.4 42.7 95.0 49.9 22.2 10.3 29.6 34.6 32.8 10.7 68.2 67.9 32.4 56.1 7.7 39.3 11.7 52.6 69.9 75.4 22.5 15.0 36.2 16.0 14.0 56.8 5.9 60.3 12.1 26.8 6.3 17.7 30.8 38.5 40.6 13.9 36.2 21.3 10.7 14.5 14.5 23.6 21.2 9.2 14.1 4.6 12.9 72.2 7.9 18.0 9.4 20.1 11.5 37.8 14.8 74.4 24.2 20.8 12.3 8.0 21.6 32.6 29.1 14.9 49.2 9.7 16.7 3.6 5.4 63.1 17.9 14.0 3.6 1.6 3.7 0.8 1.1 1.0 0.2 0.7 1.1 0.5 1.4 0.5 0.8 8.1 0.6 3.9 1.0 1.5 0.6 119.3 103.4 104.6 110.9 106.6 107.0 118.5 127.8 118.3 124.9 132.1 95.0 38.7 22.4 19.2 16.3 9.1 15.7 36.0 7.9 10.8 50.1 31.5 24.4 1.1 37.1 9.2 44.1 37.5 26.3 9.2 107.4 80.3 24.0 77.7 22.3 16.1 48.5 20.0 56.0 27.2 28.0 31.8 27.4 12.2 26.4 0.0 36.7 84.3 110.5 23.7 28.6 24.4 30.2 12.2 27.1 16.3 151.4 35.4 22.7 21.4 25.3 10.1 69.7 12.3 8.5 14.3 56.6 67.9 56.8 27.0 67.5 66.9 109.2 7.6 69.0 85.5 30.9 32.2 120.8 24.6 19.3 24.0 34.2 10.6 34.2 24.4 47.9 PIP5K1C "KIAA0589, LCCS3, PIP5Kgamma" ENSG00000186111 "Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma" O60331 19 3630183-3700468 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell adhesion, Chemotaxis, Endocytosis, Exocytosis, Phagocytosis" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Bipolar cells: 56.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "U-2197: 75.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017168 Approved Approved Nucleoplasm,Cytosol No No "Cluster 10: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Cytosol" "HPA017168: AB_1855395" "unprognostic (1.20e-1)" "prognostic favorable (1.79e-4)" "unprognostic (1.36e-3)" "prognostic favorable (7.28e-5)" "unprognostic (7.03e-2)" "unprognostic (4.02e-3)" "unprognostic (5.80e-3)" "unprognostic (8.50e-2)" "unprognostic (1.31e-1)" "unprognostic (2.57e-3)" "prognostic favorable (2.32e-4)" "unprognostic (1.51e-1)" "prognostic favorable (3.00e-4)" "unprognostic (2.25e-1)" "unprognostic (1.84e-1)" "unprognostic (2.30e-1)" "unprognostic (2.70e-1)" 22.1 15.6 30.7 11.5 36.6 3.4 19.2 19.4 66.4 24.0 0.0 62.2 8.6 44.9 7.6 20.3 29.8 8.2 32.2 40.2 5.0 15.8 8.7 22.6 6.5 13.3 7.7 22.2 18.0 10.7 20.6 11.2 12.9 33.9 4.5 13.2 18.1 25.1 17.7 16.0 24.1 16.0 0.0 22.4 29.7 61.4 19.5 5.3 21.1 4.8 4.2 39.4 24.7 33.2 18.9 18.0 13.4 18.0 25.5 21.0 20.3 36.1 22.4 15.2 12.3 16.1 5.2 7.8 13.6 39.0 16.5 16.4 6.5 11.7 6.2 28.7 11.9 9.0 15.0 13.1 22.0 9.4 26.7 23.7 9.9 12.4 4.1 9.9 25.6 11.5 14.1 13.5 14.4 15.7 11.2 6.6 14.4 6.8 24.6 21.4 7.2 11.2 11.5 15.9 13.7 12.0 18.7 10.1 11.1 16.6 7.9 14.1 57.3 21.3 11.8 75.1 17.0 16.0 14.3 3.5 27.6 19.2 15.0 1.0 0.7 0.0 0.7 0.5 0.2 0.6 0.5 0.4 0.8 0.3 0.2 0.4 0.5 0.5 0.8 0.5 0.4 0.6 30.7 36.6 19.4 66.4 40.2 5.0 13.3 7.7 12.9 0.0 19.5 33.2 20.3 6.4 5.0 8.8 6.2 5.4 3.0 6.1 7.4 56.8 9.6 6.6 7.5 7.2 3.0 16.5 37.5 7.8 10.6 12.2 1.9 7.9 11.6 6.4 29.0 22.1 8.4 2.1 30.6 7.1 7.4 10.7 7.1 11.6 1.3 10.7 16.1 4.0 15.7 30.3 17.9 9.7 6.1 19.6 13.2 24.0 14.9 15.5 5.4 22.5 15.0 14.3 11.3 9.0 6.8 12.1 13.2 24.0 5.7 4.4 7.2 6.4 4.1 26.8 13.1 8.4 10.4 18.6 11.8 7.8 6.8 16.4 8.0 11.9 7.2 5.3 PITPNM3 "ACKR6, CORD5, NIR1, RDGBA3" ENSG00000091622 "PITPNM family member 3" Q9BZ71 17 6451263-6556555 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 60.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 20.5;Hepatic stellate cells: 27.8;Inhibitory neurons: 24.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 23 "neutrophil: 2.2" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.2" "Cell line enhanced" "Detected in some" "HaCaT: 17.7;HeLa: 14.8;hTCEpi: 50.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022432, HPA059005" Enhanced Approved "Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 64: Macrophages - Immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA022432: AB_2670936, HPA059005: AB_2683876" "unprognostic (2.97e-2)" "unprognostic (8.60e-3)" "unprognostic (1.45e-2)" "unprognostic (1.52e-1)" "unprognostic (2.69e-2)" "prognostic favorable (3.67e-6)" "unprognostic (1.25e-2)" "unprognostic (6.86e-2)" "unprognostic (3.66e-2)" "unprognostic (3.01e-2)" "unprognostic (2.99e-3)" "unprognostic (3.58e-2)" "unprognostic (2.41e-1)" "unprognostic (9.60e-2)" "unprognostic (1.61e-1)" "unprognostic (3.55e-1)" "unprognostic (2.63e-1)" 1.3 3.1 23.6 1.1 20.7 0.1 1.4 7.3 23.7 3.1 0.0 7.5 1.3 1.9 3.4 17.8 4.3 1.8 1.3 19.1 1.6 2.8 1.4 3.1 0.2 0.0 0.8 26.6 1.7 0.9 2.0 0.1 0.0 4.5 3.7 7.9 4.7 8.9 0.9 17.0 2.7 4.0 0.5 60.8 6.8 4.2 4.6 0.4 2.7 0.9 1.1 1.7 6.4 13.0 9.0 0.9 0.7 0.3 0.1 0.2 0.7 0.6 0.2 0.8 0.6 0.6 6.3 0.2 3.3 0.2 2.4 17.7 0.3 3.7 0.3 0.3 0.6 0.1 14.8 0.2 0.9 0.4 0.6 0.2 50.4 1.0 2.8 4.1 0.4 0.7 0.1 0.0 0.6 0.8 0.1 0.2 1.0 4.5 2.5 0.3 1.9 0.1 1.2 0.1 0.4 0.5 8.1 3.8 0.2 0.3 1.3 0.0 0.3 0.4 3.2 0.6 2.1 0.5 0.2 0.0 0.6 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 23.6 20.7 7.3 23.7 19.1 1.6 0.0 0.8 0.0 0.5 4.6 13.0 1.5 3.2 16.5 3.6 0.2 5.1 2.2 9.6 2.2 13.5 1.3 1.8 2.0 4.3 11.4 1.8 4.2 0.1 0.2 11.1 0.0 2.2 4.1 10.1 1.0 7.8 1.2 0.0 20.5 0.5 0.0 1.6 4.6 10.3 5.7 1.6 27.8 1.6 0.1 5.0 24.2 3.7 4.1 4.1 0.4 1.8 0.6 0.3 0.0 2.8 0.1 0.6 0.0 0.5 1.6 10.0 5.7 0.0 0.2 2.4 0.6 0.3 7.8 11.9 0.0 12.0 1.9 3.4 1.7 11.5 5.8 0.1 0.7 7.1 6.5 5.2 PKD1L1 PRO19563 ENSG00000158683 "Polycystin 1 like 1, transient receptor potential channel interacting" Q8TDX9 7 47740202-47948466 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" Heterotaxy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Adipocytes: 9.1;Astrocytes: 13.4;Early spermatids: 11.8;Excitatory neurons: 25.7;Inhibitory neurons: 37.9;Microglial cells: 15.0;Oligodendrocyte precursor cells: 11.6;Oligodendrocytes: 17.1" "Cancer enhanced" "Detected in single" "testis cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "T-47d: 5.9;U-266/70: 14.7;U-266/84: 5.7" "Not detected" "Not detected" "HPA020422, HPA022424" Uncertain NA NA "Cluster 11: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA020422: AB_1855434, HPA022424: AB_1855435" "unprognostic (5.47e-2)" "unprognostic (5.33e-3)" "unprognostic (1.49e-2)" "unprognostic (9.74e-2)" "unprognostic (4.03e-2)" "unprognostic (6.31e-2)" "unprognostic (2.52e-2)" "unprognostic (1.11e-1)" "unprognostic (9.63e-3)" "unprognostic (7.96e-2)" "unprognostic (1.78e-2)" "unprognostic (2.21e-1)" "unprognostic (1.88e-4)" "unprognostic (1.88e-3)" "unprognostic (2.56e-1)" "unprognostic (2.50e-1)" "unprognostic (1.90e-1)" 1.7 0.1 1.1 0.4 0.9 1.1 0.5 2.1 1.9 0.2 0.0 0.4 0.9 0.3 0.6 0.4 0.3 0.4 2.6 0.4 1.3 0.3 0.8 0.4 0.9 0.5 0.7 0.3 0.3 0.1 0.4 0.6 0.7 0.3 0.5 1.7 0.4 0.1 2.8 0.5 0.4 0.4 0.1 0.3 0.4 1.5 0.8 1.5 0.4 3.3 0.6 0.6 0.1 1.1 0.4 0.7 0.6 0.8 0.1 0.0 1.2 0.3 0.2 0.2 0.4 0.8 0.4 0.3 0.3 0.4 0.4 0.8 0.5 0.6 0.6 0.2 0.4 0.3 0.3 0.8 0.0 0.5 0.3 0.2 0.1 0.3 0.2 0.2 1.1 0.4 0.4 1.1 0.5 0.2 0.3 0.3 0.4 0.0 0.2 0.2 0.3 0.3 0.1 0.7 0.5 0.4 0.5 0.3 0.4 0.5 5.9 0.1 0.1 0.5 1.1 0.2 0.3 14.7 5.7 0.5 0.2 0.2 0.3 0.9 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.1 0.2 0.1 0.1 1.1 0.9 2.1 1.9 0.4 1.3 0.5 0.7 0.7 0.1 0.8 1.1 9.1 0.0 0.0 13.4 0.3 0.1 0.0 0.0 0.0 3.1 0.1 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 11.8 0.5 0.1 3.7 0.0 0.0 25.7 0.2 0.2 1.7 0.0 0.3 0.0 0.2 2.2 0.1 1.4 1.7 37.9 0.7 0.0 0.3 0.0 5.3 0.3 0.2 0.0 15.0 0.0 0.5 0.0 11.6 17.1 0.0 0.0 0.0 0.4 0.1 0.3 0.0 0.0 1.5 0.0 0.4 0.2 1.4 0.6 0.0 0.0 0.0 0.1 0.3 0.8 0.0 PKHD1 "ARPKD, FCYT, FPC, TIGM1" ENSG00000170927 "PKHD1 ciliary IPT domain containing fibrocystin/polyductin" P08F94 6 51615299-52087613 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "epididymis: 4.7;kidney: 13.6;pancreas: 9.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 60.1;Collecting duct cells: 46.0;Early spermatids: 293.6;Late spermatids: 83.1" "Group enriched" "Detected in some" 5 "pancreatic cancer: 1.4;renal cancer: 5.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "RPTEC TERT1: 10.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA031227 Enhanced "Intracellular and membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 29: Early spermatids - Spermatogenesis" "HPA031227: AB_10602068" "unprognostic (6.34e-3)" "unprognostic (5.51e-2)" "unprognostic (8.80e-3)" "unprognostic (1.35e-1)" "unprognostic (3.80e-2)" "unprognostic (1.29e-2)" "unprognostic (4.03e-2)" "unprognostic (6.42e-2)" "unprognostic (7.08e-2)" "unprognostic (2.44e-2)" "unprognostic (1.02e-2)" "unprognostic (2.62e-2)" "prognostic favorable (9.74e-8)" "unprognostic (2.33e-2)" "unprognostic (1.09e-1)" "unprognostic (1.12e-1)" "unprognostic (1.48e-2)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.7 0.0 0.1 1.1 0.0 0.0 0.0 13.6 1.5 0.0 0.0 0.1 0.1 0.0 9.4 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 1.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.3 10.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.3 1.4 60.1 0.0 46.0 0.0 0.1 0.0 0.1 1.9 18.2 293.6 0.2 0.0 0.3 0.0 0.0 3.2 0.9 0.1 0.1 2.6 0.4 0.0 0.0 0.0 3.7 0.1 0.0 2.8 0.0 0.0 0.0 0.0 83.1 2.1 0.5 5.4 0.0 0.0 3.1 0.0 0.5 0.7 2.6 0.0 0.4 0.0 0.4 0.0 23.3 0.0 0.1 0.0 0.0 0.1 15.0 1.7 0.0 0.0 0.0 0.3 0.0 0.1 0.8 PKNOX2 ENSG00000165495 "PBX/knotted 1 homeobox 2" Q96KN3 11 125164687-125433389 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 36.3" "Cell type enhanced" "Detected in many" "Astrocytes: 31.3;Early spermatids: 46.8;Excitatory neurons: 132.9;Inhibitory neurons: 137.4;Oligodendrocyte precursor cells: 85.5" "Cancer enhanced" "Detected in many" "melanoma: 8.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 39.1;AN3-CA: 9.6;hTEC/SVTERT24-B: 7.8;LHCN-M2: 11.6;SK-MEL-30: 7.8;WM-115: 21.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028867, CAB034342, HPA055368, HPA066962" Supported Enhanced "Nucleoplasm,Cytokinetic bridge" Yes NA "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Cytokinetic bridge" "CAB034342: AB_2164138, HPA028867: AB_2672802, HPA055368: AB_2682796, HPA066962: AB_2685757" "unprognostic (2.91e-2)" "unprognostic (1.62e-1)" "unprognostic (2.10e-2)" "unprognostic (7.26e-2)" "unprognostic (9.46e-2)" "unprognostic (3.97e-2)" "unprognostic (2.41e-1)" "unprognostic (2.12e-2)" "unprognostic (1.56e-1)" "unprognostic (2.44e-2)" "unprognostic (7.66e-2)" "unprognostic (3.70e-1)" "unprognostic (4.10e-6)" "unprognostic (1.76e-3)" "unprognostic (7.11e-2)" "unprognostic (1.71e-2)" "unprognostic (6.48e-3)" 3.6 3.3 2.6 2.0 5.8 0.0 1.2 1.4 12.7 3.2 8.1 2.8 0.9 3.3 2.7 1.4 6.1 1.8 7.3 4.8 0.6 3.0 0.5 10.0 1.4 3.0 0.3 14.9 3.9 0.9 5.6 8.4 1.3 6.3 1.4 2.8 2.5 5.1 15.0 2.4 1.7 2.6 2.6 2.3 2.3 4.8 0.8 3.1 12.1 36.3 1.1 3.1 2.7 3.1 0.0 0.0 39.1 9.6 0.7 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 4.8 0.0 0.0 0.2 0.2 0.0 0.0 0.0 1.2 0.0 0.0 2.0 0.0 7.8 0.1 0.0 0.0 0.0 0.0 0.0 11.6 0.3 0.0 0.0 3.9 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.8 6.1 0.0 0.2 0.0 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 21.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 5.8 1.4 12.7 4.8 0.6 3.0 0.3 1.3 2.6 0.8 3.1 0.6 0.0 0.0 31.3 0.0 0.9 0.0 0.0 0.0 0.9 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 1.4 46.8 0.0 1.1 0.5 0.0 0.0 132.9 0.2 0.0 3.1 0.0 0.0 0.0 12.2 1.8 0.0 0.3 8.4 137.4 0.0 0.0 0.0 0.3 9.6 5.0 0.0 8.8 22.5 0.0 2.9 0.0 85.5 3.8 0.1 0.0 17.7 0.0 1.9 0.0 0.1 0.0 0.3 6.6 8.8 2.9 1.2 0.4 0.0 0.4 0.1 0.0 6.9 0.0 0.0 PLA1A ps-PLA1 ENSG00000144837 "Phospholipase A1 member A" Q53H76 3 119597875-119629811 "Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 138.4;parathyroid gland: 65.8;seminal vesicle: 67.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 14.7;Endothelial cells: 14.3;Hepatocytes: 26.0;Langerhans cells: 15.6;Peritubular cells: 14.3" "Group enriched" "Detected in many" 5 "liver cancer: 14.8;melanoma: 55.4;prostate cancer: 24.2;renal cancer: 21.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "SK-MEL-30: 25.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059740 Approved "Nucleoplasm,Nuclear speckles,Cytoplasmic bodies" "Secreted in other tissues" NA NA 420000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Cytoplasmic bodies" Nucleoplasm "HPA059740: AB_2684118" "unprognostic (1.35e-1)" "prognostic favorable (2.81e-7)" "unprognostic (2.24e-2)" "unprognostic (3.46e-2)" "unprognostic (3.18e-2)" "unprognostic (1.94e-2)" "unprognostic (1.11e-2)" "unprognostic (2.43e-1)" "unprognostic (3.87e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" "unprognostic (9.09e-2)" "unprognostic (1.55e-3)" "unprognostic (9.53e-3)" "unprognostic (3.94e-2)" "unprognostic (1.67e-1)" "unprognostic (2.67e-1)" 4.9 0.7 12.1 3.5 11.3 0.3 3.4 11.6 16.3 4.7 26.8 2.7 1.1 4.7 138.4 1.5 5.7 2.8 4.9 12.5 12.0 7.7 39.6 21.2 15.6 13.2 12.3 1.1 3.7 65.8 1.7 9.8 13.2 9.1 2.5 1.0 3.5 67.2 16.2 0.8 3.5 8.8 13.4 1.0 4.4 3.7 14.7 1.6 6.9 3.1 8.7 3.9 1.9 12.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.8 0.3 0.5 0.1 0.0 0.2 0.0 0.0 25.0 0.0 0.0 0.0 1.3 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 12.1 11.3 11.6 16.3 12.5 12.0 13.2 12.3 13.2 13.4 14.7 12.4 6.5 0.0 1.7 0.0 0.0 0.6 0.5 0.4 0.6 0.0 0.1 0.1 2.8 2.8 1.0 14.7 0.0 0.2 0.1 0.0 1.9 4.7 6.6 0.1 0.1 14.3 1.8 0.0 0.2 2.2 0.0 1.6 0.0 0.9 1.3 0.7 7.9 26.0 1.6 0.0 0.1 0.1 0.0 1.0 15.6 3.2 0.3 5.4 1.8 4.7 4.2 0.0 0.0 0.0 0.0 1.3 0.6 14.3 0.0 0.5 0.0 5.1 7.5 0.1 0.0 0.9 5.9 0.0 0.2 0.0 0.6 1.9 0.1 0.0 0.1 0.2 PLA2G12A PLA2G12 ENSG00000123739 "Phospholipase A2 group XIIA" Q9BZM1 4 109709989-109730070 "Enzymes, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 147.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035908, HPA035909" Approved "Secreted to blood" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 22: Non-specific - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 51: Myeloid cells - Hemostasis" "HPA035908: AB_2674856, HPA035909: AB_10672074" "unprognostic (8.40e-2)" "unprognostic (3.87e-1)" "unprognostic (3.81e-3)" "unprognostic (3.09e-2)" "unprognostic (2.10e-1)" "unprognostic (1.35e-1)" "unprognostic (4.26e-2)" "unprognostic (1.77e-1)" "unprognostic (1.90e-1)" "unprognostic (2.71e-3)" "unprognostic (1.02e-1)" "unprognostic (8.42e-2)" "prognostic favorable (2.54e-9)" "unprognostic (3.10e-1)" "unprognostic (1.39e-1)" "unprognostic (9.16e-3)" "unprognostic (3.64e-2)" 10.0 9.0 11.4 3.4 12.7 6.2 12.0 12.6 13.8 8.4 11.9 11.5 10.5 8.1 7.3 11.4 8.4 7.3 16.0 10.4 12.2 14.7 21.2 7.4 4.0 13.9 14.4 10.5 34.5 23.0 12.5 3.7 13.1 15.1 10.8 15.5 11.8 7.1 22.1 9.3 10.6 7.0 14.2 5.2 9.8 5.0 12.7 4.9 17.8 19.3 4.6 7.0 7.6 15.1 17.2 6.2 4.8 7.4 15.0 14.9 9.4 14.9 11.0 8.5 8.9 15.6 29.1 24.5 11.6 11.1 14.0 9.3 14.9 20.1 13.0 8.3 22.8 8.7 17.5 11.5 14.2 19.2 5.9 15.1 22.9 8.6 21.3 14.3 7.7 22.5 48.8 10.7 14.7 30.3 15.7 8.6 8.6 39.0 24.1 9.3 14.3 19.5 16.2 25.0 30.8 10.1 13.7 35.5 11.9 12.3 21.3 4.0 10.4 12.4 10.1 12.9 10.8 18.5 36.0 17.8 13.5 11.0 15.5 5.4 4.1 2.7 6.2 2.7 5.7 3.7 7.8 6.0 8.2 4.3 8.7 8.0 1.8 5.0 4.5 7.0 8.3 12.1 11.4 12.7 12.6 13.8 10.4 12.2 13.9 14.4 13.1 14.2 12.7 15.1 11.7 25.6 21.8 14.4 11.7 36.7 36.3 39.7 25.0 52.5 27.5 18.3 56.8 30.0 24.9 22.0 50.1 42.7 8.3 31.5 27.4 15.0 26.7 15.1 9.5 17.1 107.7 48.4 24.1 25.9 53.4 29.3 32.6 14.0 14.0 147.4 23.9 103.1 19.4 26.9 28.6 52.8 34.6 22.4 17.1 8.7 33.2 64.6 30.2 18.7 6.1 47.7 13.4 16.6 20.1 13.9 38.9 34.6 20.6 67.8 78.9 19.2 16.4 42.3 19.7 38.2 21.1 62.7 47.5 39.0 42.6 34.5 14.3 28.6 58.9 44.9 PLA2G12B PLA2G13 ENSG00000138308 "Phospholipase A2 group XIIB" Q9BX93 10 72934762-72954806 "Metabolic proteins, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 33.1;kidney: 14.4;liver: 71.0" "Group enriched" "Detected in some" 4 "Hepatocytes: 52.2;Proximal enterocytes: 70.0" "Cancer enriched" "Detected in many" 8 "liver cancer: 35.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "CACO-2: 9.1;Hep G2: 15.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA057745, HPA059562" Approved "Secreted to blood" NA NA 2300000 "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "HPA057745: AB_2683514, HPA059562: AB_2684064" "unprognostic (1.11e-2)" "unprognostic (2.66e-2)" "unprognostic (2.02e-3)" "unprognostic (3.41e-1)" "unprognostic (1.68e-1)" "unprognostic (1.89e-1)" "unprognostic (1.26e-1)" "unprognostic (3.14e-2)" 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.3 0.0 0.0 2.2 27.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.0 14.4 71.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.1 0.0 0.0 0.0 0.0 33.1 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.1 0.3 0.6 0.0 0.0 0.0 0.0 1.3 0.0 0.0 3.1 1.5 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 1.8 52.2 0.0 0.0 0.3 2.4 0.0 0.8 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 6.3 0.0 0.0 0.0 70.0 13.4 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 6.3 0.0 PLAAT3 "AdPLA, H-REV107-1, HRASLS3, HREV107, HREV107-3, MGC118754., PLA2G16, PLAAT-3" ENSG00000176485 "Phospholipase A and acyltransferase 3" P53816 11 63573195-63616883 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction, Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 318.7;brain: 394.8" "Cell type enhanced" "Detected in some" "Adipocytes: 80.5;Cardiomyocytes: 151.9;Cytotrophoblasts: 137.4;Extravillous trophoblasts: 365.5;Hofbauer cells: 71.0;Syncytiotrophoblasts: 290.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 187.8" "Group enriched" "Detected in all" 6 "dendritic cells: 187.8;T-cells: 55.0" "Cell line enhanced" "Detected in many" "A549: 135.1;ASC diff: 148.2;CAPAN-2: 247.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011749, HPA058997" Approved Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" Mitochondria "HPA011749: , HPA058997: AB_2683874" "unprognostic (5.18e-2)" "unprognostic (3.67e-2)" "unprognostic (7.92e-2)" "unprognostic (3.89e-2)" "unprognostic (1.94e-1)" "unprognostic (1.78e-1)" "unprognostic (1.13e-1)" "unprognostic (3.06e-2)" "unprognostic (6.97e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (5.58e-6)" "unprognostic (6.38e-2)" "unprognostic (1.93e-3)" "unprognostic (1.62e-1)" "unprognostic (1.75e-1)" "prognostic favorable (2.54e-5)" "unprognostic (2.35e-1)" 318.7 36.2 208.5 10.2 287.0 3.1 166.8 234.7 261.6 13.3 142.8 32.8 8.7 17.6 26.6 13.2 33.0 29.1 103.0 197.7 215.3 65.0 76.5 37.6 11.6 283.0 250.7 73.4 32.4 28.6 33.4 40.3 279.8 16.4 7.6 26.6 28.9 29.9 108.9 10.7 21.8 15.8 241.2 15.9 31.9 54.7 237.1 7.1 41.2 118.7 4.4 26.7 9.6 394.8 87.7 135.1 3.7 0.2 148.2 25.1 24.1 3.2 26.9 22.3 11.2 30.8 247.1 0.0 55.3 6.9 72.4 4.4 127.4 6.8 16.9 108.0 5.0 1.3 33.3 5.4 87.8 0.0 1.3 15.2 0.7 55.4 2.2 88.1 35.4 0.0 1.6 9.6 24.0 15.3 0.2 0.6 10.8 55.0 43.0 0.0 0.0 8.7 71.2 12.3 1.7 9.7 18.0 51.5 28.7 54.6 111.6 4.5 52.2 10.0 0.7 34.0 7.7 39.6 28.0 0.3 40.1 0.0 1.0 0.1 21.1 0.1 55.0 9.1 30.3 7.4 12.1 40.5 6.4 1.2 3.9 30.0 1.3 21.0 0.6 187.8 9.3 27.2 208.5 287.0 234.7 261.6 197.7 215.3 283.0 250.7 279.8 241.2 237.1 394.8 80.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 151.9 0.0 0.0 0.0 0.0 137.4 18.6 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 365.5 14.7 0.0 0.0 0.0 0.0 0.0 0.0 71.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 290.6 2.0 0.0 0.0 0.0 PLAC9 ENSG00000189129 "Placenta associated 9" Q5JTB6 10 80131682-80145359 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 124.3" "Cell type enhanced" "Detected in many" "Fibroblasts: 926.5;Leydig cells: 873.5;Peritubular cells: 659.7;Sertoli cells: 295.9;Smooth muscle cells: 446.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.0" "Cell line enhanced" "Detected in many" "ASC diff: 98.5;ASC TERT1: 85.3;BEWO: 32.1;HSkMC: 28.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 37.9" HPA043469 Uncertain "Secreted - unknown location" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA043469: AB_10795770" "unprognostic (1.72e-1)" "unprognostic (4.22e-2)" "unprognostic (5.01e-3)" "unprognostic (1.78e-2)" "unprognostic (2.76e-1)" "unprognostic (3.93e-1)" "unprognostic (5.57e-3)" "unprognostic (5.88e-3)" "unprognostic (8.45e-2)" "prognostic unfavorable (6.60e-4)" "unprognostic (1.30e-2)" "unprognostic (1.09e-1)" "unprognostic (4.23e-3)" "unprognostic (4.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.14e-1)" "unprognostic (2.82e-3)" 112.3 18.4 10.2 6.6 9.2 1.2 85.7 10.3 15.5 77.3 53.3 22.1 4.0 26.9 5.0 21.4 30.4 9.0 124.3 14.3 5.9 17.9 6.4 56.1 2.7 5.9 5.8 11.5 5.7 4.1 4.9 12.5 6.4 35.9 4.6 0.6 20.1 7.6 16.9 47.8 19.7 6.5 6.5 5.0 21.4 14.9 6.9 2.2 44.6 19.2 1.9 54.0 75.7 8.5 0.2 0.0 0.8 0.0 98.5 85.3 32.1 10.3 8.7 0.9 1.2 0.0 0.7 0.0 0.2 6.0 0.1 0.8 0.1 0.0 0.0 0.8 0.3 0.0 0.5 0.0 16.4 0.0 2.3 28.7 0.0 2.1 1.2 10.6 3.4 0.4 0.0 0.4 0.0 0.3 0.1 0.6 1.9 0.4 1.5 0.0 0.1 1.5 0.0 0.6 0.0 1.8 0.0 1.2 0.7 0.2 0.1 0.2 3.6 6.6 3.6 21.0 0.2 0.7 0.9 0.1 1.9 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 10.2 9.2 10.3 15.5 14.3 5.9 5.9 5.8 6.4 6.5 6.9 8.5 246.2 3.2 1.8 0.0 1.6 126.4 0.7 1.1 8.0 0.4 7.4 14.0 24.4 0.0 0.3 0.0 0.0 7.0 3.6 0.1 0.0 0.3 4.6 3.1 75.7 102.5 1.8 0.0 0.5 0.2 17.7 926.5 5.6 4.4 1.3 0.1 115.6 0.3 14.1 0.0 0.5 0.0 0.0 0.0 191.3 26.7 873.5 7.9 136.9 7.5 0.0 50.2 0.0 0.0 0.2 0.7 0.0 659.7 2.1 1.0 0.0 0.2 0.9 1.7 295.9 89.7 446.6 2.6 2.9 4.6 126.3 11.5 14.1 1.1 0.0 1.8 PLCB4 ENSG00000101333 "Phospholipase C beta 4" Q15147 20 9068763-9481242 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 55.6;salivary gland: 57.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 105.9;Horizontal cells: 164.9;Inhibitory neurons: 113.8;Microglial cells: 183.6;Oligodendrocyte precursor cells: 168.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.5" "Region enhanced" "Detected in all" "cerebellum: 55.6" "Immune cell enriched" "Detected in single" 18 "plasmacytoid DC: 3.0" "Lineage enriched" "Detected in single" 18 "dendritic cells: 3.0" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 91.4;hTERT-HME1: 45.9;LHCN-M2: 77.6;OE19: 48.2;RPTEC TERT1: 96.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007951 Approved Approved Nucleoplasm,Microtubules NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 21: Non-specific - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Microtubules Nucleoplasm "HPA007951: AB_2667944" "unprognostic (3.88e-2)" "unprognostic (3.62e-1)" "unprognostic (1.19e-2)" "prognostic favorable (2.11e-4)" "unprognostic (1.44e-2)" "unprognostic (9.72e-3)" "unprognostic (3.32e-3)" "unprognostic (2.57e-2)" "unprognostic (7.75e-2)" "unprognostic (4.23e-2)" "unprognostic (5.21e-3)" "unprognostic (1.35e-1)" "unprognostic (4.64e-3)" "unprognostic (7.12e-2)" "unprognostic (1.37e-1)" "unprognostic (2.22e-1)" "unprognostic (4.45e-2)" 6.3 7.2 8.6 3.4 3.7 0.5 7.0 55.6 6.3 4.6 31.0 20.5 2.6 8.2 24.4 9.0 15.0 5.9 17.9 2.5 10.8 3.0 0.3 5.4 1.7 13.4 17.8 2.1 2.1 0.7 8.2 6.5 12.0 9.7 17.9 15.1 57.4 6.1 2.7 4.6 4.2 9.1 5.3 1.3 14.4 2.4 23.3 4.5 32.7 6.8 2.3 8.2 5.3 6.5 0.0 15.1 7.9 0.0 0.0 0.4 0.1 35.8 9.5 10.9 6.1 3.4 2.6 0.0 0.6 91.4 39.0 0.1 2.3 7.6 14.7 0.0 5.3 3.8 5.7 0.0 1.6 0.0 0.0 2.3 3.0 12.7 45.9 18.7 0.1 0.0 4.3 0.4 77.6 5.0 0.0 0.0 8.8 48.2 10.4 0.0 0.0 0.7 96.9 5.8 25.5 18.4 0.0 23.8 15.1 10.5 19.2 0.2 0.5 11.2 0.9 1.2 14.2 0.0 0.0 0.0 1.7 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.0 0.0 0.0 8.6 3.7 55.6 6.3 2.5 10.8 13.4 17.8 12.0 5.3 23.3 6.5 37.8 6.4 0.5 60.1 0.3 2.4 3.8 1.5 2.2 82.9 5.7 5.3 72.6 0.0 8.9 5.5 0.0 0.0 4.5 17.9 0.0 0.7 1.4 46.2 4.6 40.4 42.0 0.0 105.9 0.2 0.0 9.0 18.8 53.5 0.0 36.6 1.8 0.0 0.1 164.9 113.8 36.4 14.2 0.0 2.1 1.2 1.5 0.8 7.2 183.6 0.6 2.9 0.0 168.9 2.9 7.1 9.7 20.7 0.2 8.5 2.1 1.2 39.5 6.6 13.1 10.5 36.0 1.5 2.0 0.5 1.0 0.1 1.4 4.8 40.4 2.5 PLCG2 ENSG00000197943 "Phospholipase C gamma 2" P16885 16 81739097-81962685 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 706.3;choroid plexus: 347.5" "Cell type enhanced" "Detected in many" "Adipocytes: 187.0;Bipolar cells: 224.8;Muller glia cells: 221.7;Rod photoreceptor cells: 196.2" "Cancer enhanced" "Detected in all" "renal cancer: 9.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 183.3;HMC-1: 84.2;REH: 75.1;U-698: 403.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004280, HPA020099, HPA020100" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 8200 "Cluster 5: Granulocytes - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Cytosol" Nucleoplasm "CAB004280: AB_628120, HPA020099: AB_1855324, HPA020100: AB_1855325" "unprognostic (2.86e-2)" "unprognostic (1.34e-1)" "unprognostic (1.09e-3)" "unprognostic (1.10e-1)" "unprognostic (1.58e-1)" "prognostic favorable (6.71e-4)" "unprognostic (6.23e-2)" "unprognostic (5.01e-2)" "unprognostic (2.22e-1)" "unprognostic (4.58e-2)" "unprognostic (4.66e-2)" "unprognostic (1.71e-2)" "prognostic favorable (4.88e-4)" "unprognostic (1.52e-2)" "unprognostic (1.21e-1)" "unprognostic (2.89e-1)" "unprognostic (3.40e-3)" 9.0 4.2 69.4 33.0 141.3 30.3 8.5 706.3 105.2 5.0 347.5 8.6 17.3 8.6 22.5 4.6 5.5 13.4 4.3 40.1 122.6 23.4 14.3 9.4 66.8 301.3 122.7 1.6 3.9 2.8 1.2 8.2 207.3 2.8 7.0 0.5 7.1 3.4 1.9 4.0 19.4 8.8 241.5 34.8 8.7 2.0 283.3 10.0 6.9 3.6 72.0 10.1 3.9 437.2 1.4 3.2 0.6 2.9 0.2 0.2 4.0 0.3 0.4 2.3 0.8 0.9 8.1 183.3 30.1 0.2 7.4 4.2 4.0 0.5 1.4 1.4 2.1 22.1 0.4 0.3 1.2 22.3 84.2 0.3 1.8 1.3 1.0 0.3 4.2 8.1 2.5 15.0 0.4 5.7 2.6 55.5 3.1 2.3 1.3 75.1 0.1 23.7 0.5 3.9 1.4 0.4 5.0 1.6 1.5 3.9 3.3 67.7 1.1 0.4 3.2 0.4 0.6 35.2 61.4 403.4 0.3 30.0 1.6 9.4 12.1 76.2 1.9 16.1 0.9 51.1 0.6 2.9 10.7 49.6 0.8 1.9 65.7 41.3 36.8 7.0 0.5 6.9 69.4 141.3 706.3 105.2 40.1 122.6 301.3 122.7 207.3 241.5 283.3 437.2 187.0 12.8 54.0 0.0 138.3 2.9 1.6 2.3 1.8 224.8 139.5 113.0 7.2 28.6 13.1 16.5 104.3 13.6 94.0 0.4 13.7 2.6 20.5 65.5 88.0 61.7 21.5 23.2 0.7 0.0 2.2 30.6 16.8 86.6 40.4 29.0 37.1 43.2 27.7 101.0 0.8 2.7 65.1 47.4 9.4 30.7 11.1 46.7 8.8 95.5 21.8 221.7 47.4 2.0 1.3 0.1 9.8 4.9 138.6 3.5 5.5 5.9 6.9 196.2 6.6 28.0 51.9 4.8 2.9 3.0 2.3 11.1 48.2 8.7 1.9 6.5 PLCL1 "PLC-L, PLCE, PLCL, PPP1R127, PRIP" ENSG00000115896 "Phospholipase C like 1 (inactive)" Q15111 2 197804593-198572581 "Metabolic proteins, Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.3;tongue: 40.8" "Cell type enriched" "Detected in many" 10 "Oligodendrocytes: 2062.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.4" "Lineage enriched" "Detected in single" 6 "T-cells: 1.4" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 8.7;K-562: 15.6;Karpas-707: 10.7;MOLT-4: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031849 Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA031849: AB_10602192" "unprognostic (7.77e-3)" "unprognostic (2.57e-1)" "unprognostic (2.09e-1)" "unprognostic (5.18e-3)" "unprognostic (4.40e-2)" "unprognostic (7.14e-2)" "unprognostic (2.05e-1)" "unprognostic (4.42e-3)" "unprognostic (1.07e-1)" "unprognostic (1.32e-1)" "unprognostic (3.02e-2)" "unprognostic (7.42e-2)" "prognostic favorable (3.91e-7)" "unprognostic (1.07e-4)" "unprognostic (6.74e-2)" "unprognostic (1.68e-1)" "unprognostic (3.20e-2)" 4.0 4.1 15.6 2.7 40.5 1.6 2.4 32.5 21.4 4.5 9.5 4.0 0.6 14.8 3.1 3.6 3.3 3.0 32.4 13.8 30.8 31.5 0.5 3.2 3.4 42.6 37.4 7.0 1.6 14.8 2.1 7.9 39.2 10.5 1.3 4.0 2.3 7.1 30.8 0.9 1.8 6.0 22.6 1.9 2.2 1.7 27.7 17.2 3.3 40.8 2.6 4.1 1.9 65.3 0.0 0.0 0.1 0.0 1.6 0.4 0.0 0.4 0.2 0.1 0.1 0.0 0.1 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 1.5 0.0 0.2 0.0 1.8 4.2 0.0 0.0 0.0 0.0 8.7 2.9 15.6 10.7 0.1 0.4 11.4 0.0 0.1 0.0 0.0 0.0 0.0 4.7 0.2 0.0 1.6 0.9 1.8 0.0 2.5 0.8 0.2 0.0 0.7 0.2 0.0 0.0 0.1 4.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.6 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.0 1.4 0.0 15.6 40.5 32.5 21.4 13.8 30.8 42.6 37.4 39.2 22.6 27.7 65.3 7.0 19.2 4.4 44.4 0.9 1.3 0.8 0.0 0.6 14.8 2.0 1.8 159.0 1.5 1.9 14.7 0.0 0.1 0.8 1.8 58.7 0.9 15.5 2.0 102.7 5.4 1.8 0.0 201.0 0.4 0.0 6.0 1.1 1.9 6.3 3.8 0.4 0.0 3.1 15.2 160.9 0.0 2.0 4.1 2.0 3.8 1.8 4.6 0.0 49.6 2.9 2.7 0.0 181.5 2062.6 0.2 0.0 7.9 3.8 0.6 0.6 52.4 2.2 1.2 32.9 5.4 31.8 1.0 1.8 0.2 1.3 0.1 8.2 1.6 0.1 0.3 PLEK P47 ENSG00000115956 Pleckstrin P08567 2 68365282-68397453 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 604.8" "Cell type enhanced" "Detected in many" "dendritic cells: 310.7;Hofbauer cells: 220.3;Kupffer cells: 213.9;Langerhans cells: 456.5;Macrophages: 412.7;monocytes: 178.3;NK-cells: 355.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 552.9;HL-60: 126.7;HMC-1: 202.5;NB-4: 187.5;THP-1: 215.6;U-266/84: 147.8;U-698: 147.1;U-937: 342.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031838, HPA057341" Enhanced Approved Nucleoli NA NA 380000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoli "HPA031838: AB_10602146, HPA057341: AB_2732609" "unprognostic (2.57e-2)" "unprognostic (5.18e-2)" "unprognostic (1.87e-3)" "unprognostic (4.52e-3)" "unprognostic (3.52e-1)" "unprognostic (3.08e-2)" "unprognostic (4.67e-2)" "unprognostic (3.40e-2)" "unprognostic (4.00e-2)" "unprognostic (1.24e-1)" "unprognostic (1.07e-1)" "unprognostic (1.22e-1)" "prognostic unfavorable (1.95e-4)" "unprognostic (3.57e-1)" "unprognostic (4.42e-2)" "unprognostic (2.03e-1)" "unprognostic (1.56e-1)" 36.4 9.8 4.9 99.4 7.1 604.8 8.2 6.0 10.0 6.9 6.5 13.2 10.4 4.7 3.3 6.0 7.2 21.0 5.4 4.9 5.3 4.0 27.5 35.6 129.9 8.0 6.1 2.6 2.7 2.7 1.9 29.2 8.1 4.2 18.8 0.5 5.7 3.1 1.7 3.4 13.0 22.2 7.3 93.5 11.3 3.2 7.2 33.7 3.8 5.2 118.2 52.3 2.5 12.3 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 93.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 552.9 0.0 0.0 0.0 126.7 202.5 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.3 58.9 0.0 0.0 0.2 187.5 0.0 0.0 0.0 1.5 0.1 27.3 0.0 0.0 0.0 0.1 0.4 0.0 0.4 0.0 0.0 215.6 0.1 0.0 0.4 0.1 0.5 7.9 147.8 147.1 0.2 342.5 0.1 231.9 297.5 429.2 298.5 351.6 157.6 157.7 52.2 218.7 229.6 103.6 14.5 161.8 573.9 249.5 390.8 474.8 5.7 606.9 4.9 7.1 6.0 10.0 4.9 5.3 8.0 6.1 8.1 7.3 7.2 12.3 3.4 19.2 24.6 0.0 77.0 6.5 0.3 0.0 0.0 0.0 1.4 3.7 2.3 1.5 15.5 1.8 0.0 1.2 310.7 0.0 0.0 0.2 1.5 0.2 0.3 6.3 0.0 21.9 0.6 0.6 1.8 10.2 1.5 0.3 62.0 0.0 5.7 1.5 220.3 0.0 0.2 0.0 0.0 213.9 456.5 5.1 0.6 412.7 17.8 20.6 178.3 0.0 355.3 0.0 0.1 0.1 0.1 0.4 48.4 0.0 0.0 0.7 13.1 0.1 13.1 1.1 1.8 0.8 0.9 0.6 6.7 2.6 78.3 0.4 0.0 0.3 PLEKHG1 "ARHGEF41, KIAA1209" ENSG00000120278 "Pleckstrin homology and RhoGEF domain containing G1" Q9ULL1 6 150599883-150843665 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 31.2" "Cell type enhanced" "Detected in many" "Adipocytes: 91.2;Astrocytes: 98.6;Endothelial cells: 58.4;Microglial cells: 131.2;Oligodendrocytes: 168.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 31 "memory B-cell: 23.9;naive B-cell: 22.9" "Lineage enriched" "Detected in single" 31 "B-cells: 23.9" "Cell line enhanced" "Detected in many" "AF22: 17.6;HAP1: 26.4;Karpas-707: 23.4;U-698: 16.6" "Region enhanced" "Detected in all" "thalamus: 51.3" "Low region specificity" "Detected in all" "HPA027128, HPA027319, HPA028270" Approved Enhanced Nucleoplasm Yes No "Cluster 37: B-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA027128: AB_2672124, HPA027319: AB_10600306, HPA028270: AB_10611388" "unprognostic (2.93e-1)" "unprognostic (3.44e-1)" "unprognostic (3.04e-3)" "unprognostic (2.34e-1)" "unprognostic (1.05e-1)" "unprognostic (2.80e-3)" "unprognostic (1.85e-1)" "unprognostic (4.82e-2)" "unprognostic (2.10e-1)" "unprognostic (1.60e-1)" "unprognostic (3.47e-2)" "unprognostic (1.50e-1)" "unprognostic (4.62e-3)" "unprognostic (3.63e-1)" "unprognostic (4.30e-2)" "unprognostic (3.83e-1)" "unprognostic (2.15e-2)" 15.1 1.6 9.8 9.4 12.3 2.4 13.7 15.5 8.9 7.5 3.9 5.9 4.9 5.6 10.8 9.4 8.7 7.9 6.9 5.8 8.7 7.7 4.9 10.4 14.7 19.5 16.2 3.1 2.7 6.7 3.6 14.2 18.3 2.7 5.9 4.7 3.5 4.9 3.5 7.4 6.6 5.6 18.2 31.2 4.5 6.3 19.1 22.4 5.7 5.0 13.9 9.1 5.3 21.5 0.0 0.2 17.6 0.1 0.0 0.0 12.6 0.0 0.0 0.0 0.0 10.1 4.4 7.2 6.8 0.0 1.6 2.5 26.4 2.4 0.0 11.4 2.9 0.4 1.4 0.0 0.0 0.0 1.9 1.1 6.7 0.0 0.2 0.0 11.0 5.9 0.0 23.4 0.0 0.3 2.3 0.1 1.3 7.0 0.7 1.2 0.0 0.0 5.1 11.9 0.5 0.1 0.1 3.1 2.2 1.9 0.0 0.1 11.2 0.1 2.4 0.0 4.9 0.0 0.0 16.6 0.0 0.0 3.6 0.0 0.0 0.0 0.1 0.0 0.7 23.9 0.4 0.6 0.0 22.9 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.7 9.8 12.3 15.5 8.9 5.8 8.7 19.5 16.2 18.3 18.2 19.1 21.5 91.2 0.0 6.2 98.6 50.3 4.2 0.5 5.5 2.8 0.9 2.0 3.3 2.1 1.5 6.8 7.3 0.0 5.5 0.7 7.2 3.9 2.6 3.8 20.7 6.2 58.4 5.4 5.0 12.8 1.1 1.6 11.8 7.1 19.2 0.0 7.9 35.0 4.3 0.6 0.0 5.8 8.2 8.2 5.9 3.8 1.6 0.3 2.0 5.4 131.2 4.7 11.3 0.0 14.1 168.5 9.4 12.4 0.4 5.2 1.1 3.9 3.6 9.6 0.7 0.0 2.0 3.0 0.7 1.5 6.2 3.7 2.9 5.1 1.1 5.5 3.6 PLEKHM3 "DAPR, PLEKHM1L" ENSG00000178385 "Pleckstrin homology domain containing M3" Q6ZWE6 2 207821288-208025527 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 99.1;Inhibitory neurons: 70.5;Microglial cells: 36.5;Oligodendrocyte precursor cells: 45.2;Oligodendrocytes: 86.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035046 Uncertain Approved Vesicles,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 23: Testis - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol Vesicles "HPA035046: AB_10603128" "unprognostic (3.62e-1)" "unprognostic (1.58e-2)" "unprognostic (8.27e-2)" "unprognostic (3.18e-2)" "unprognostic (5.66e-2)" "unprognostic (4.77e-2)" "unprognostic (6.06e-2)" "unprognostic (8.20e-2)" "unprognostic (4.13e-2)" "unprognostic (2.92e-3)" "unprognostic (2.17e-1)" "unprognostic (1.09e-1)" "unprognostic (4.86e-4)" "unprognostic (2.42e-1)" "unprognostic (3.12e-1)" "unprognostic (5.72e-2)" "unprognostic (1.33e-2)" 2.9 4.1 2.3 1.3 2.6 4.3 2.4 0.4 2.9 2.7 0.0 3.1 0.9 2.5 0.9 1.6 2.0 1.4 2.9 2.8 2.1 1.9 3.1 2.9 1.5 2.0 2.6 3.1 2.2 4.0 2.5 1.4 2.2 2.5 1.5 8.3 2.2 1.4 2.4 2.6 1.9 1.9 0.2 1.9 2.2 1.7 1.3 2.2 3.6 1.6 1.4 1.9 2.5 2.0 0.7 0.7 1.6 0.9 2.7 2.7 2.5 1.5 1.6 1.2 1.1 0.9 0.7 0.6 1.5 1.8 1.2 0.8 1.7 2.2 1.6 1.2 2.6 1.3 2.2 1.3 1.6 1.4 0.7 2.2 2.6 1.3 1.6 1.9 1.3 2.1 0.8 1.7 1.5 0.4 1.7 0.9 1.6 0.5 0.8 1.3 1.4 1.3 0.6 0.9 3.5 1.8 1.4 0.1 1.5 2.7 0.4 1.1 1.8 1.9 1.1 1.1 1.0 2.0 2.4 0.6 2.2 0.8 1.4 1.3 0.8 0.4 0.9 0.3 0.3 0.9 0.8 0.8 0.7 0.6 1.0 0.8 2.6 0.9 0.7 0.7 0.5 0.2 2.3 2.6 0.4 2.9 2.8 2.1 2.0 2.6 2.2 0.2 1.3 2.0 6.3 19.2 21.7 29.0 2.7 0.0 0.2 0.1 0.6 3.1 4.1 3.7 1.2 1.5 5.6 1.8 12.5 0.3 4.1 1.2 0.0 3.1 2.5 4.1 6.3 2.3 0.0 4.0 99.1 3.4 0.5 3.0 2.0 4.7 0.0 25.0 0.4 0.6 0.6 6.7 70.5 0.1 0.0 1.0 2.4 5.2 0.3 3.8 0.0 36.5 4.6 2.3 0.0 45.2 86.9 3.5 1.6 0.0 2.0 0.2 1.1 4.9 0.8 9.6 0.0 1.7 3.8 0.4 0.7 1.1 0.1 0.1 2.5 6.9 0.5 0.1 PLEKHO1 "CKIP-1, OC120" ENSG00000023902 "Pleckstrin homology domain containing O1" Q53GL0 1 150149183-150164720 "Predicted intracellular proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 202.3" "Cell type enhanced" "Detected in many" "Early spermatids: 245.9;Langerhans cells: 159.2;Late spermatids: 390.5;Macrophages: 147.9;monocytes: 151.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061018 Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA061018: AB_2684416" "unprognostic (1.41e-2)" "unprognostic (7.04e-3)" "unprognostic (2.01e-2)" "unprognostic (1.78e-2)" "unprognostic (3.23e-2)" "unprognostic (4.77e-2)" "unprognostic (1.62e-2)" "unprognostic (8.33e-2)" "unprognostic (3.84e-2)" "unprognostic (3.18e-2)" "unprognostic (8.71e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (6.47e-11)" "unprognostic (9.30e-2)" "unprognostic (1.72e-1)" "unprognostic (1.87e-1)" "unprognostic (6.52e-2)" 27.7 43.2 49.9 53.9 50.1 17.9 22.6 52.8 61.6 32.3 45.5 202.3 17.8 50.7 5.2 17.5 43.5 20.6 59.3 49.5 47.9 15.9 8.7 34.9 49.5 49.8 48.1 28.1 5.1 4.1 14.9 15.1 48.0 45.5 11.5 4.2 11.0 16.2 39.6 11.2 58.4 40.4 48.9 59.9 55.8 83.2 48.0 33.9 13.0 15.2 26.0 97.5 23.6 48.9 14.3 3.4 46.3 36.0 14.4 12.7 3.8 24.8 32.9 31.8 28.1 1.0 0.4 0.4 4.7 28.5 23.9 1.2 23.3 1.1 10.3 86.7 12.1 2.8 1.9 8.9 27.1 20.0 77.7 18.5 1.0 39.8 6.2 30.6 30.6 38.5 5.4 35.9 43.9 6.7 76.0 40.0 43.7 0.0 6.4 68.1 25.2 16.2 5.6 4.1 28.8 46.9 2.0 0.2 18.7 22.1 2.4 19.4 43.4 20.8 24.1 21.9 30.1 14.0 0.4 9.2 83.4 0.2 8.2 2.6 25.9 0.5 5.6 24.8 6.0 20.0 8.2 5.9 20.1 17.2 5.6 4.7 30.9 4.1 23.4 27.3 6.7 9.2 49.9 50.1 52.8 61.6 49.5 47.9 49.8 48.1 48.0 48.9 48.0 48.9 23.5 35.3 8.9 32.3 65.1 21.5 92.7 2.9 4.6 7.9 11.8 17.9 36.4 2.8 2.9 0.0 0.0 1.7 97.5 0.5 1.9 8.8 245.9 17.9 50.2 58.9 17.8 4.2 13.5 7.8 3.3 29.4 4.6 22.0 5.7 24.5 42.5 1.8 107.1 8.4 24.3 0.9 10.2 85.5 159.2 390.5 17.4 147.9 24.9 21.5 151.1 34.0 23.7 9.0 1.6 10.7 0.0 24.5 23.7 50.1 0.2 0.5 1.3 6.2 72.3 7.5 105.0 122.5 17.5 2.9 14.2 1.5 45.6 8.6 0.4 23.0 PLPBP PROSC ENSG00000147471 "Pyridoxal phosphate binding protein" O94903 8 37762595-37779768 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 101.8;Exocrine glandular cells: 49.8;Hofbauer cells: 47.3;Proximal tubular cells: 82.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017033, HPA023646, HPA023733" Approved Enhanced Cytosol NA NA 34000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Cytosol "CAB017033: , HPA023646: AB_1855741, HPA023733: AB_1855742" "unprognostic (1.55e-2)" "unprognostic (2.17e-2)" "unprognostic (2.14e-2)" "unprognostic (2.95e-2)" "unprognostic (1.34e-1)" "unprognostic (2.35e-2)" "unprognostic (2.36e-1)" "unprognostic (7.78e-3)" "unprognostic (1.80e-1)" "unprognostic (4.28e-2)" "unprognostic (2.83e-2)" "unprognostic (2.59e-2)" "unprognostic (9.41e-3)" "unprognostic (3.16e-2)" "unprognostic (3.99e-2)" "unprognostic (2.90e-1)" "unprognostic (7.85e-2)" 34.2 23.1 22.2 21.2 24.3 14.6 23.3 25.3 27.1 22.1 26.8 47.2 34.5 19.2 23.3 20.2 27.5 19.1 39.2 24.0 25.0 58.5 78.2 25.7 25.0 22.8 24.9 24.7 40.3 37.4 16.2 20.1 23.7 20.2 37.9 10.9 28.3 27.8 46.4 17.0 37.3 25.9 23.7 25.0 33.5 8.4 24.5 27.4 31.8 42.1 29.0 22.9 16.1 28.6 50.3 45.4 35.1 32.0 25.9 31.1 31.6 55.2 45.8 34.7 38.9 51.6 24.3 58.4 61.9 39.9 55.5 41.4 65.4 52.5 56.6 49.9 34.3 79.4 16.4 51.7 51.6 36.8 52.5 22.9 49.8 33.0 52.0 37.6 52.3 78.3 42.8 42.1 28.7 34.8 116.4 32.4 43.0 92.8 41.9 73.6 46.6 34.8 56.5 60.0 21.5 25.1 45.4 20.0 56.8 25.4 44.2 48.6 52.1 19.1 60.7 69.8 38.1 43.3 90.9 43.0 27.4 51.8 35.0 164.3 109.6 136.1 85.6 130.0 90.0 77.8 87.8 83.6 115.2 61.9 77.0 74.3 46.9 75.9 147.4 66.5 116.7 110.2 22.2 24.3 25.3 27.1 24.0 25.0 22.8 24.9 23.7 23.7 24.5 28.6 35.9 9.6 26.5 0.0 6.7 0.0 0.0 0.0 0.0 0.0 27.8 23.0 0.0 0.0 8.1 31.3 0.0 21.2 20.0 0.0 101.8 38.2 0.0 12.8 20.7 13.5 0.0 0.0 0.0 49.8 31.6 13.9 0.0 19.6 12.6 14.8 0.0 0.0 47.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.9 0.0 0.0 11.9 0.0 0.0 0.0 0.0 33.2 0.0 0.0 1.8 0.0 0.0 82.2 13.8 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 12.9 9.8 17.1 0.0 0.0 PLPP2 "LPP2, PAP-2c, PPAP2C" ENSG00000141934 "Phospholipid phosphatase 2" O43688 19 281040-291403 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 204.5;Ductal cells: 352.1;Proximal enterocytes: 209.8;Rod photoreceptor cells: 234.9;Urothelial cells: 205.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.2;MAIT T-cell: 6.6" "Lineage enriched" "Detected in single" 41 "T-cells: 6.6" "Cell line enhanced" "Detected in many" "A549: 144.1;CAPAN-2: 154.6;OE19: 255.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055540, HPA058428" Uncertain Supported "Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "HPA055540: AB_2682839, HPA058428: " "prognostic unfavorable (4.55e-4)" "unprognostic (8.91e-3)" "unprognostic (1.06e-1)" "prognostic favorable (3.21e-8)" "unprognostic (2.95e-1)" "unprognostic (1.36e-1)" "unprognostic (3.83e-3)" "unprognostic (5.48e-2)" "unprognostic (1.59e-1)" "unprognostic (5.67e-2)" "unprognostic (1.18e-3)" "unprognostic (3.85e-1)" "unprognostic (3.53e-3)" "unprognostic (1.06e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-3)" "unprognostic (1.36e-3)" 4.8 13.2 37.7 8.5 61.6 0.0 36.9 57.1 50.0 63.4 26.2 40.5 62.7 16.8 8.4 27.2 81.8 52.4 1.7 38.8 43.5 11.5 3.7 8.3 1.4 57.3 53.6 2.7 37.3 19.5 11.8 3.6 56.2 31.7 32.1 29.6 105.7 32.9 0.6 53.2 51.0 6.4 44.8 4.7 50.3 7.6 49.2 5.2 5.7 0.5 6.0 36.5 14.2 83.9 85.5 144.1 2.1 0.1 0.0 0.3 0.2 8.2 0.0 25.3 18.9 41.7 154.6 0.0 88.3 11.9 0.1 45.3 0.0 17.6 11.1 0.8 2.6 0.0 55.9 0.0 28.6 0.0 5.5 5.2 7.6 12.7 16.7 53.4 4.2 0.0 0.7 0.1 0.0 98.5 0.4 0.1 61.5 255.8 0.0 0.0 0.0 2.4 62.1 13.7 17.4 40.9 23.3 38.3 60.3 5.8 50.0 2.5 4.5 55.7 36.5 0.5 61.9 0.8 101.7 70.4 15.5 0.0 46.9 0.0 0.0 0.0 3.2 0.0 6.6 0.0 1.3 1.6 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 37.7 61.6 57.1 50.0 38.8 43.5 57.3 53.6 56.2 44.8 49.2 83.9 17.0 6.4 7.5 0.0 1.5 0.0 134.2 0.0 8.0 19.7 137.1 149.9 0.0 204.5 35.3 22.0 10.4 0.5 2.7 77.0 3.9 352.1 0.3 115.2 9.2 15.2 8.5 0.0 0.0 139.5 15.1 3.0 91.3 90.1 1.3 0.0 0.0 0.5 0.9 16.8 0.0 38.8 0.0 1.0 0.0 1.6 0.0 1.9 0.0 0.0 2.6 21.7 0.0 0.0 0.0 128.8 85.2 0.0 1.6 97.4 209.8 1.4 91.1 234.9 0.0 0.8 2.7 0.6 35.1 20.3 0.0 0.8 3.5 0.1 87.2 205.8 PLPP4 "DPPL2, PPAPDC1, PPAPDC1A" ENSG00000203805 "Phospholipid phosphatase 4" Q5VZY2 10 120457227-120592065 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "brain: 12.2" "Cell type enhanced" "Detected in some" "Cholangiocytes: 11.5;Distal tubular cells: 7.9;Early spermatids: 10.9;Erythroid cells: 9.7;Late spermatids: 10.7;Leydig cells: 19.3;Peritubular cells: 7.9;Proximal tubular cells: 9.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "hTERT-RPE1: 14.2;U-251 MG: 10.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045188 Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA045188: AB_2679246" "unprognostic (8.19e-2)" "unprognostic (2.94e-2)" "unprognostic (8.86e-2)" "unprognostic (1.90e-3)" "unprognostic (3.45e-1)" "unprognostic (2.92e-2)" "unprognostic (2.69e-1)" "unprognostic (2.26e-3)" "unprognostic (1.55e-1)" "unprognostic (8.62e-3)" "unprognostic (2.70e-3)" "unprognostic (1.89e-1)" "unprognostic (2.40e-3)" "unprognostic (3.49e-2)" "unprognostic (3.75e-2)" "unprognostic (1.11e-1)" "unprognostic (1.21e-3)" 0.0 0.0 2.9 0.1 3.5 0.4 0.1 6.4 2.8 0.2 0.5 0.3 0.0 0.1 0.0 0.0 0.0 0.6 0.0 5.3 8.9 0.8 0.1 0.0 0.0 11.0 5.3 0.0 0.0 0.0 0.0 0.0 12.2 0.2 0.0 0.1 0.0 0.2 0.1 0.2 0.1 0.1 4.3 0.0 0.0 0.9 3.7 0.1 0.0 0.0 0.0 0.0 0.1 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.3 0.2 0.0 0.3 0.1 0.0 1.7 1.4 0.0 0.1 0.1 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 14.2 1.3 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.1 0.0 0.1 0.9 0.2 0.0 2.8 1.7 1.2 0.1 10.4 0.0 0.0 0.0 2.3 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 2.9 3.5 6.4 2.8 5.3 8.9 11.0 5.3 12.2 4.3 3.7 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 11.5 0.0 3.7 0.0 0.0 0.0 0.0 7.9 0.3 10.9 0.1 2.5 0.0 0.0 9.7 0.0 0.2 0.1 0.3 0.0 0.1 0.0 0.2 1.8 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 10.7 19.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 7.9 0.0 0.5 0.0 9.0 0.0 0.0 0.0 0.0 4.9 1.5 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 PLPPR1 "FLJ20300, LPPR1, MGC26189, PRG-3" ENSG00000148123 "Phospholipid phosphatase related 1" Q8TBJ4 9 101028727-101325135 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.8;kidney: 15.6" "Group enriched" "Detected in some" 4 "Distal tubular cells: 37.2;Early spermatids: 12.3;Proximal tubular cells: 39.0" "Group enriched" "Detected in some" 5 "glioma: 11.1;liver cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Hep G2: 3.7;SCLC-21H: 9.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014760, HPA014968, HPA014979" Supported Supported Nucleoplasm NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA014760: AB_2669084, HPA014968: AB_1855702, HPA014979: AB_2669130" "unprognostic (1.08e-2)" "unprognostic (2.79e-1)" "unprognostic (2.98e-2)" "unprognostic (2.54e-1)" "unprognostic (1.14e-1)" "unprognostic (7.33e-2)" "unprognostic (3.41e-1)" "prognostic favorable (1.37e-4)" "unprognostic (2.09e-1)" "unprognostic (1.14e-1)" "unprognostic (9.86e-4)" "unprognostic (1.44e-1)" "unprognostic (1.65e-6)" "unprognostic (3.68e-2)" "unprognostic (1.46e-1)" "unprognostic (2.85e-1)" "unprognostic (4.83e-2)" 0.0 0.1 9.7 0.0 12.8 0.0 0.7 7.1 12.7 0.1 5.2 0.2 0.0 0.0 2.8 0.0 0.2 0.0 0.0 10.4 9.3 15.6 3.6 1.4 0.0 10.2 9.1 0.0 0.3 0.0 0.1 0.0 9.8 0.2 0.1 1.5 0.3 0.0 0.0 0.1 0.0 0.0 9.6 0.0 0.1 0.6 10.9 0.4 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.7 9.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 12.8 7.1 12.7 10.4 9.3 10.2 9.1 9.8 9.6 10.9 11.5 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.3 2.3 0.0 1.5 0.6 0.0 0.0 0.0 0.1 0.0 37.2 0.0 12.3 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 4.3 0.0 0.1 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.2 0.0 39.0 0.0 1.0 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.2 0.0 0.2 0.0 PLS1 "I-plastin, Plastin-1" ENSG00000120756 "Plastin 1" Q14651 3 142596393-142713664 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 315.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 471.4;Intestinal goblet cells: 147.9;Paneth cells: 200.5;Proximal enterocytes: 335.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 36.0" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 2.6;NK-cells: 3.2;T-cells: 2.6" "Cell line enhanced" "Detected in many" "A-431: 90.0;BEWO: 112.3;OE19: 166.4;RPTEC TERT1: 143.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055744, HPA061936" Enhanced NA NA 56000000 "Cluster 15: NK-cells - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA055744: AB_2682903, HPA061936: " "unprognostic (1.29e-1)" "unprognostic (2.61e-1)" "unprognostic (3.15e-3)" "unprognostic (2.22e-2)" "unprognostic (1.20e-1)" "unprognostic (1.41e-2)" "unprognostic (1.13e-1)" "unprognostic (6.82e-2)" "unprognostic (2.33e-1)" "unprognostic (7.78e-2)" "prognostic unfavorable (4.84e-4)" "unprognostic (3.14e-2)" "prognostic favorable (8.76e-6)" "unprognostic (1.99e-2)" "unprognostic (8.64e-2)" "unprognostic (7.22e-2)" "unprognostic (3.82e-2)" 1.6 3.9 0.8 18.8 1.3 7.4 5.7 2.7 2.2 10.1 11.7 144.2 191.6 3.3 3.1 9.6 7.7 27.7 1.2 1.1 1.4 26.7 27.5 14.8 1.7 3.3 0.3 0.9 12.2 15.7 6.2 1.5 3.2 3.1 139.1 24.9 9.1 1.9 0.9 3.6 315.6 4.3 0.3 0.9 45.8 7.5 0.4 5.9 7.7 0.9 2.9 19.6 3.7 1.4 90.0 69.2 4.8 10.4 0.7 0.0 112.3 1.7 2.3 9.4 20.1 31.7 68.8 15.2 35.8 0.1 31.9 18.9 18.8 28.7 20.0 5.5 27.0 27.2 10.2 11.4 0.9 13.0 1.7 0.1 4.7 17.8 11.4 14.8 4.5 16.4 11.8 1.7 1.1 21.0 21.4 7.0 18.9 166.4 25.9 8.7 20.3 12.7 143.6 81.7 24.1 9.7 10.0 7.0 7.8 13.3 55.6 2.2 1.2 1.1 11.3 3.5 21.3 12.7 12.6 18.1 3.2 12.8 3.5 1.9 0.2 2.6 1.5 0.2 2.0 0.3 1.8 2.0 0.4 0.3 2.2 2.6 1.8 3.2 0.2 0.5 1.3 1.0 0.8 1.3 2.7 2.2 1.1 1.4 3.3 0.3 3.2 0.3 0.4 1.4 0.6 54.5 38.0 1.3 1.6 2.9 4.1 23.2 2.8 3.4 9.7 4.2 3.1 54.3 46.8 44.1 16.7 5.8 0.7 471.4 21.5 21.8 64.3 22.2 1.8 0.7 53.9 5.9 18.7 34.0 1.9 1.1 50.0 26.8 8.9 32.3 1.1 31.5 0.6 5.0 25.2 147.9 24.4 1.6 1.0 20.5 1.2 1.4 1.8 5.6 0.8 2.8 0.0 4.0 3.1 70.2 200.5 0.0 2.8 6.8 335.1 40.6 42.2 13.4 0.0 1.2 1.9 4.6 4.1 7.6 3.3 1.4 1.8 1.3 85.2 20.7 PLSCR3 ENSG00000187838 "Phospholipid scramblase 3" Q9NRY6 17 7389727-7394842 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 3.0;Ductal cells: 5.8;Exocrine glandular cells: 3.6;monocytes: 2.0;Pancreatic endocrine cells: 8.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048387, HPA068609" Supported Supported Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "HPA048387: AB_2680381, HPA068609: AB_2686011" "unprognostic (1.86e-2)" "unprognostic (5.29e-2)" "unprognostic (2.29e-2)" "unprognostic (1.56e-2)" "unprognostic (4.36e-2)" "unprognostic (5.02e-2)" "unprognostic (2.27e-2)" "unprognostic (9.71e-2)" "unprognostic (1.75e-3)" "unprognostic (1.91e-1)" "unprognostic (1.11e-2)" "unprognostic (1.77e-2)" "unprognostic (2.11e-5)" "unprognostic (1.24e-2)" "unprognostic (1.48e-1)" "unprognostic (1.97e-1)" "unprognostic (2.55e-2)" 39.5 21.1 7.4 11.0 7.5 3.3 35.0 7.0 8.5 46.2 7.2 27.1 3.1 44.5 5.9 37.4 29.4 6.5 32.0 6.8 7.4 23.5 14.4 32.8 10.5 8.5 7.3 30.5 16.7 5.6 16.4 7.0 7.6 24.7 3.4 1.2 22.9 8.0 21.2 35.2 21.9 12.3 7.4 40.7 21.9 6.1 8.1 6.4 22.8 11.1 10.5 34.8 38.1 7.7 26.7 6.6 5.7 17.2 19.4 32.8 6.8 24.1 22.1 21.3 19.3 9.8 6.6 7.3 19.4 35.1 9.0 37.6 7.0 41.4 10.9 19.0 4.0 6.7 9.2 6.0 23.6 2.5 8.2 22.6 25.4 20.7 30.1 32.0 32.3 14.5 4.1 5.6 27.1 14.3 7.7 2.0 5.1 7.1 18.3 15.1 4.3 8.3 20.1 17.7 4.7 15.6 13.9 8.8 5.9 5.0 16.0 1.3 53.2 13.9 14.5 15.7 10.3 6.2 7.4 3.0 22.4 8.4 15.9 7.0 24.5 2.8 39.5 34.1 40.8 32.2 72.8 40.7 24.1 32.5 59.2 36.1 2.6 18.0 30.2 2.8 83.5 33.3 7.4 7.5 7.0 8.5 6.8 7.4 8.5 7.3 7.6 7.4 8.1 7.7 1.0 3.2 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 5.8 0.0 0.1 1.0 1.0 0.0 0.0 0.0 3.6 0.3 1.0 0.0 0.1 1.3 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.6 0.1 0.0 0.0 PLVAP "FELS, gp68, PV-1, PV1" ENSG00000130300 "Plasmalemma vesicle associated protein" Q9BX97 19 17351450-17377342 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 436.2" "Group enriched" "Detected in many" 4 "Adipocytes: 439.2;Endothelial cells: 344.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 35.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 35.2" "Cell line enriched" "Detected in some" 27 "EFO-21: 549.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002279 Supported Approved "Plasma membrane,Centrosome,Cytosol" NA NA 53000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Plasma membrane, Centrosome" "HPA002279: AB_1079636" "unprognostic (3.19e-1)" "unprognostic (8.22e-2)" "unprognostic (7.87e-2)" "unprognostic (2.38e-2)" "unprognostic (1.93e-2)" "unprognostic (2.49e-3)" "unprognostic (4.17e-3)" "unprognostic (1.01e-1)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.53e-2)" "unprognostic (8.96e-2)" "unprognostic (4.24e-3)" "unprognostic (4.70e-3)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (8.17e-2)" 283.0 51.1 2.7 54.6 3.1 1.7 210.5 2.9 4.2 102.7 18.2 95.7 86.7 90.0 5.1 48.9 83.3 139.2 92.5 3.3 3.1 153.0 6.9 31.0 50.5 3.7 3.5 16.7 96.1 98.6 64.3 48.8 3.6 68.4 22.3 0.0 77.9 38.0 32.7 58.9 103.3 50.5 3.6 166.7 116.6 4.4 3.5 18.9 436.2 12.9 16.2 104.4 80.8 4.1 0.3 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 549.1 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 9.5 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 1.1 20.0 0.0 2.3 0.1 0.3 0.5 2.2 2.5 0.0 0.2 0.0 0.0 0.2 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.7 35.2 0.0 0.6 2.7 3.1 2.9 4.2 3.3 3.1 3.7 3.5 3.6 3.6 3.5 4.1 439.2 6.4 0.0 0.3 0.7 22.9 1.0 0.0 8.0 0.0 2.7 3.3 3.7 0.0 0.0 0.0 0.0 0.1 5.1 0.0 0.0 1.7 3.6 0.4 0.3 344.9 0.0 0.4 0.4 2.5 0.1 48.9 0.0 0.3 0.0 0.4 79.6 0.2 1.8 0.0 0.3 0.0 0.0 3.5 28.8 0.8 0.0 5.5 23.2 6.5 0.0 0.5 0.0 0.0 0.3 0.1 0.0 0.0 7.6 1.5 0.0 0.0 0.0 0.1 0.0 1.4 6.1 0.5 0.7 2.9 16.8 0.1 1.4 0.7 0.0 2.3 PLXNA2 "FLJ11751, FLJ30634, KIAA0463, OCT, PLXN2" ENSG00000076356 "Plexin A2" O75051 1 208022242-208244384 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 35.1" "Cell type enhanced" "Detected in many" "Astrocytes: 100.6;Excitatory neurons: 134.7;Horizontal cells: 249.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 52.8;HaCaT: 55.4;HUVEC TERT2: 70.3;TIME: 162.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009763 Approved NA NA 1400000 "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB009763: AB_2166388" "unprognostic (8.25e-2)" "unprognostic (3.91e-2)" "unprognostic (8.85e-2)" "unprognostic (2.77e-2)" "unprognostic (8.66e-2)" "unprognostic (2.07e-1)" "unprognostic (1.97e-2)" "unprognostic (4.84e-2)" "unprognostic (6.88e-3)" "unprognostic (7.06e-2)" "unprognostic (2.61e-1)" "unprognostic (8.41e-2)" "unprognostic (4.49e-3)" "unprognostic (1.26e-1)" "unprognostic (5.40e-2)" "unprognostic (1.27e-2)" "unprognostic (2.40e-1)" 7.9 1.4 6.6 2.1 9.1 0.4 4.9 10.5 11.2 3.9 19.0 9.0 6.8 6.0 2.0 15.4 5.2 4.0 8.8 10.0 1.6 3.4 2.4 14.3 1.0 2.2 7.8 13.8 35.1 1.3 3.0 8.5 3.2 4.1 7.2 3.7 4.1 3.1 9.6 9.5 7.7 5.9 4.5 1.3 9.0 0.6 2.7 4.3 6.8 9.4 2.4 9.4 6.3 7.7 6.4 3.7 6.9 1.0 7.6 14.7 52.8 5.0 3.1 3.0 0.5 0.2 0.1 0.0 9.8 3.9 1.3 55.4 0.1 31.4 0.9 1.9 1.1 0.0 6.9 3.7 3.2 0.0 0.2 3.9 10.0 2.4 14.2 2.0 70.3 0.0 0.0 0.0 30.7 0.7 0.1 0.1 1.1 11.2 9.4 0.0 7.0 4.7 5.7 4.0 2.0 12.5 5.9 4.5 5.5 13.3 0.5 0.0 162.9 1.1 1.7 5.9 10.4 0.3 0.0 0.0 6.5 0.0 2.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.6 9.1 10.5 11.2 10.0 1.6 2.2 7.8 3.2 4.5 2.7 7.7 50.7 28.9 28.6 100.6 1.7 4.8 16.2 12.9 30.1 12.7 2.9 2.2 5.8 7.2 25.6 0.0 2.1 5.3 0.8 64.6 1.9 4.2 0.9 13.8 0.9 48.1 9.1 0.0 134.7 15.3 2.5 9.6 44.4 9.5 6.3 1.1 36.8 5.9 3.3 249.0 62.9 29.0 8.2 5.5 6.0 0.6 9.9 4.4 5.4 54.4 1.4 0.4 1.0 44.7 3.1 23.3 52.2 6.8 1.7 8.2 33.6 2.2 8.5 2.7 6.6 26.3 8.1 1.9 1.0 41.1 10.5 1.9 1.1 1.4 26.5 22.7 PLXND1 KIAA0620 ENSG00000004399 "Plexin D1" Q9Y4D7 3 129555214-129606676 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 107.3;Endothelial cells: 102.1;Hepatic stellate cells: 132.1;Hofbauer cells: 81.5;Kupffer cells: 75.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 10.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 392.3;HSkMC: 286.1;HUVEC TERT2: 346.1;TIME: 414.4" "Group enriched" "Detected in all" 4 "amygdala: 36.6;basal ganglia: 33.1;cerebral cortex: 27.4;hippocampal formation: 26.3" "Low region specificity" "Detected in all" CAB020819 Approved NA NA 120000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "CAB020819: " "unprognostic (8.97e-3)" "unprognostic (1.95e-1)" "unprognostic (6.30e-2)" "unprognostic (8.35e-2)" "unprognostic (1.28e-2)" "unprognostic (3.00e-3)" "unprognostic (6.35e-2)" "unprognostic (4.51e-2)" "unprognostic (3.69e-1)" "unprognostic (3.02e-3)" "unprognostic (3.78e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (5.93e-7)" "unprognostic (1.30e-1)" "unprognostic (3.21e-2)" "unprognostic (3.17e-2)" "unprognostic (1.00e-2)" 72.6 22.1 32.0 37.4 38.1 26.5 47.4 36.2 35.6 58.4 26.1 19.5 6.0 33.5 17.6 21.5 35.0 39.4 39.8 29.3 34.2 24.7 18.3 67.5 34.7 48.7 43.5 16.3 13.9 18.0 11.1 112.4 43.8 19.0 16.9 3.5 13.3 27.0 12.9 19.5 20.9 52.6 38.8 33.6 15.8 10.8 49.0 62.7 29.5 39.8 23.2 37.1 26.8 43.2 10.0 57.7 47.4 16.3 392.3 167.9 98.4 42.8 123.1 25.5 29.5 13.4 8.1 2.1 179.9 152.9 13.2 0.6 25.9 0.6 7.5 1.9 3.2 40.7 30.2 61.4 44.8 13.5 11.0 286.1 1.7 26.4 2.8 36.6 346.1 2.1 14.5 1.5 34.8 31.0 2.4 44.2 11.8 2.4 8.0 47.4 32.0 51.8 10.2 2.3 27.6 1.1 11.0 3.5 15.9 107.6 15.5 59.7 414.4 21.5 28.5 0.6 32.4 1.9 2.2 19.9 7.5 29.2 19.0 0.0 10.7 0.0 1.7 5.1 6.8 0.0 1.2 1.4 2.9 0.0 0.0 0.1 0.2 3.1 5.2 3.6 0.0 1.7 32.0 38.1 36.2 35.6 29.3 34.2 48.7 43.5 43.8 38.8 49.0 43.2 107.3 3.2 27.2 12.4 3.6 8.0 0.4 2.1 0.6 0.1 7.6 3.4 10.6 5.7 3.1 0.0 0.0 7.1 16.9 0.2 0.0 1.4 1.4 3.7 52.5 102.1 13.1 12.6 10.4 3.5 16.4 19.5 5.6 6.2 22.2 1.3 132.1 7.7 81.5 0.0 0.6 3.2 6.1 75.6 31.8 1.8 38.8 41.7 8.8 27.2 29.4 6.5 10.3 0.5 27.7 2.7 0.1 13.9 12.9 0.5 0.0 0.3 1.2 0.3 32.9 14.4 37.1 0.6 4.0 1.5 4.4 5.3 14.4 49.5 0.5 0.6 PMM1 Sec53 ENSG00000100417 "Phosphomannomutase 1" Q92871 22 41576900-41589871 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 176.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030712, HPA074950" Uncertain Supported Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 45: Enterocytes - Digestion" Cytosol "HPA030712: AB_10669600, HPA074950: " "unprognostic (2.66e-1)" "prognostic favorable (5.92e-4)" "unprognostic (3.25e-2)" "prognostic favorable (6.09e-6)" "unprognostic (1.25e-1)" "unprognostic (2.85e-2)" "unprognostic (1.01e-2)" "unprognostic (1.95e-2)" "unprognostic (2.24e-3)" "unprognostic (1.78e-1)" "prognostic favorable (2.05e-4)" "unprognostic (6.56e-3)" "unprognostic (5.76e-3)" "unprognostic (2.78e-2)" "unprognostic (1.72e-1)" "unprognostic (1.40e-2)" "unprognostic (2.70e-1)" 47.0 51.7 49.0 12.0 50.4 26.2 39.0 47.0 65.0 34.4 41.2 33.6 37.7 26.9 19.2 73.7 34.7 18.8 26.5 49.5 52.1 59.4 64.2 33.8 17.5 46.9 47.2 48.1 45.0 15.4 19.5 14.2 51.2 26.5 20.3 13.6 23.3 20.2 16.2 33.2 33.8 19.9 47.8 13.7 65.7 32.6 49.8 14.3 13.8 11.4 16.8 31.7 28.0 49.7 16.0 29.0 19.6 42.5 54.3 84.0 23.0 61.7 69.8 56.0 61.0 23.0 15.3 14.9 20.3 74.4 40.0 23.4 25.8 40.0 31.1 31.2 38.6 3.8 34.8 49.2 85.8 22.6 23.8 70.4 38.2 58.3 24.2 61.9 9.3 23.8 16.9 51.9 76.5 42.0 17.1 32.5 6.2 75.1 38.2 13.1 20.7 30.7 24.0 17.1 5.8 11.2 50.5 18.1 75.2 15.2 20.3 24.4 7.5 63.2 34.3 59.4 32.8 33.2 34.0 24.3 70.3 18.8 38.7 21.0 22.0 44.8 27.7 18.5 22.3 17.8 27.6 22.8 23.2 20.5 29.4 21.1 28.8 13.4 22.9 9.2 49.4 18.8 49.0 50.4 47.0 65.0 49.5 52.1 46.9 47.2 51.2 47.8 49.8 49.7 7.8 35.3 106.4 16.3 15.0 14.8 10.2 22.5 20.5 16.7 22.8 29.3 12.4 82.9 25.8 35.0 6.2 57.1 10.0 104.8 107.6 31.8 17.1 77.7 34.2 6.9 48.7 19.3 14.9 11.0 91.1 33.3 36.2 51.4 3.8 60.9 8.9 83.5 34.5 28.6 10.9 58.1 14.2 14.4 13.5 15.3 28.0 16.3 44.4 3.7 21.9 67.1 16.5 4.0 7.1 10.8 117.0 30.5 17.7 8.5 176.1 138.5 34.8 22.6 39.5 18.9 36.9 72.6 10.9 23.1 14.1 65.3 21.0 37.9 55.3 8.2 PMPCB "MPPB, MPPP52" ENSG00000105819 "Peptidase, mitochondrial processing subunit beta" O75439 7 103297435-103329511 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040674, HPA074168" Approved Enhanced Mitochondria No No 19000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA040674: AB_10961998, HPA074168: AB_2686671" "prognostic favorable (2.79e-4)" "unprognostic (3.11e-1)" "unprognostic (7.18e-3)" "unprognostic (3.03e-1)" "unprognostic (3.65e-2)" "unprognostic (1.72e-1)" "unprognostic (1.06e-1)" "unprognostic (7.67e-2)" "unprognostic (7.74e-2)" "unprognostic (1.21e-1)" "unprognostic (1.38e-1)" "unprognostic (1.42e-3)" "prognostic favorable (2.95e-8)" "unprognostic (2.59e-2)" "unprognostic (9.79e-2)" "unprognostic (2.40e-1)" "unprognostic (4.39e-2)" 30.8 42.0 16.9 22.3 18.2 53.5 32.5 18.9 22.1 33.3 24.7 33.4 38.0 29.9 26.2 27.7 29.3 25.1 44.9 18.8 18.1 47.4 46.1 22.6 36.4 16.5 16.6 35.4 41.1 39.7 22.4 25.8 17.6 31.5 33.2 25.4 30.6 28.1 34.8 33.2 32.4 26.3 17.2 28.2 35.8 26.7 17.4 30.2 33.4 38.2 33.9 29.3 28.4 19.9 30.2 42.8 49.9 69.4 28.5 57.1 38.0 26.7 45.6 54.3 62.8 47.7 33.7 76.9 41.7 47.9 58.0 37.5 59.7 43.2 49.2 26.4 69.4 26.4 74.0 61.6 35.0 35.0 30.6 53.4 40.5 41.8 39.6 51.3 28.8 55.9 52.5 77.9 48.5 71.1 59.2 82.0 59.2 60.4 52.4 42.7 34.3 79.4 50.3 54.2 62.2 76.5 37.3 108.6 55.8 49.5 45.3 49.1 24.9 48.3 57.9 85.1 52.3 57.4 79.9 61.8 35.7 59.3 38.2 16.7 19.3 13.2 18.3 21.4 20.1 25.9 21.1 18.5 24.7 19.3 26.1 21.7 5.7 17.9 19.7 12.6 30.2 22.3 16.9 18.2 18.9 22.1 18.8 18.1 16.5 16.6 17.6 17.2 17.4 19.9 32.0 32.1 36.9 27.1 54.5 36.7 68.2 123.2 51.8 31.6 41.3 37.3 70.4 41.5 70.7 27.6 22.9 125.6 55.9 35.8 72.4 75.6 106.3 38.4 37.0 37.1 27.1 65.8 36.8 73.2 61.3 42.5 35.7 35.0 60.2 49.9 31.1 53.7 54.6 23.5 33.9 48.1 75.3 49.4 30.7 24.0 51.9 42.4 26.6 18.7 92.5 35.8 58.7 35.7 44.4 59.7 45.4 49.7 56.1 35.2 60.4 127.5 58.2 37.9 65.7 48.6 73.5 125.4 56.4 47.1 37.5 124.9 55.9 63.3 59.1 62.2 PNMA8B "KIAA1183, PNMAL2" ENSG00000204851 "PNMA family member 8B" Q9ULN7 19 46486906-46495879 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 14.7;brain: 41.6" "Group enriched" "Detected in some" 4 "Adipocytes: 8.3;Granulosa cells: 5.3;Theca cells: 12.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.4;AN3-CA: 1.8;SH-SY5Y: 1.4" "Low region specificity" "Detected in all" HPA054810 Enhanced NA NA "Cluster 65: Brain - Ion transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 52: Non-specific - Transcription" "HPA054810: AB_2682609" "unprognostic (1.31e-2)" "unprognostic (2.81e-2)" "unprognostic (3.27e-2)" "unprognostic (1.34e-1)" "unprognostic (5.97e-2)" "unprognostic (3.38e-3)" "unprognostic (2.90e-1)" "unprognostic (1.35e-1)" "unprognostic (4.15e-1)" "unprognostic (4.19e-3)" "unprognostic (4.26e-4)" "unprognostic (7.30e-2)" "unprognostic (5.57e-3)" "unprognostic (1.84e-2)" "unprognostic (1.07e-1)" "unprognostic (3.38e-1)" "unprognostic (1.32e-2)" 2.7 14.7 32.8 0.3 31.1 0.0 2.4 0.0 41.6 1.9 0.0 1.5 0.3 1.7 0.5 0.5 1.6 1.0 1.9 20.1 25.3 0.7 0.4 0.7 0.4 22.5 15.0 3.9 0.9 0.2 7.3 0.3 27.3 1.6 0.1 2.1 1.5 1.0 0.5 2.3 0.9 0.6 2.1 1.9 0.9 0.8 18.5 3.5 0.8 0.4 0.1 1.1 1.6 19.0 0.0 0.0 1.4 1.8 0.4 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 31.1 0.0 41.6 20.1 25.3 22.5 15.0 27.3 2.1 18.5 19.0 8.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.9 0.3 0.0 0.5 0.9 0.8 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.1 0.0 5.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 12.4 0.0 0.0 PNOC "N/OFQ, NOP, PPNOC" ENSG00000168081 Prepronociceptin Q13519 8 28316986-28343355 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Neuropeptide, Neurotransmitter, Opioid peptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.3;fallopian tube: 18.2;lymphoid tissue: 25.1" "Cell type enhanced" "Detected in some" "B-cells: 61.5;dendritic cells: 12.6;Inhibitory neurons: 23.3;Melanocytes: 14.2;Plasma cells: 80.4" "Cancer enriched" "Detected in many" 8 "ovarian cancer: 32.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 20 "memory B-cell: 231.2;naive B-cell: 260.3;plasmacytoid DC: 194.0" "Group enriched" "Detected in many" 20 "B-cells: 260.3;dendritic cells: 194.0" "Group enriched" "Detected in some" 6 "Daudi: 38.3;Karpas-707: 29.2;RPMI-8226: 11.2;U-698: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA044507, HPA056724" Enhanced "Secreted to blood" NA NA 12300 "Cluster 19: B-cells - Humoral immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA044507: AB_10795043, HPA056724: AB_2683216" "unprognostic (1.11e-1)" "unprognostic (1.77e-3)" "unprognostic (3.53e-2)" "prognostic unfavorable (2.94e-6)" "unprognostic (3.71e-2)" "unprognostic (5.16e-5)" "unprognostic (1.03e-1)" "unprognostic (1.50e-1)" "unprognostic (7.81e-4)" "unprognostic (1.48e-1)" "unprognostic (1.66e-1)" "unprognostic (9.99e-3)" "unprognostic (7.57e-9)" "unprognostic (2.19e-2)" "unprognostic (5.45e-1)" "unprognostic (3.44e-1)" "unprognostic (1.40e-1)" 0.2 0.8 5.4 9.9 5.1 2.7 0.6 1.3 10.8 0.2 1.3 2.9 4.3 0.1 0.0 0.6 18.2 1.1 0.1 2.9 9.9 0.7 0.2 1.0 25.1 10.4 6.3 0.4 0.0 0.0 0.0 0.0 9.9 0.2 1.5 0.0 1.6 0.1 0.0 0.1 5.8 0.5 14.3 14.4 3.2 0.6 4.3 2.7 0.4 0.0 23.6 3.7 0.2 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 29.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 4.0 4.4 23.0 0.1 0.1 0.0 0.2 11.5 2.3 0.2 7.7 0.1 231.2 0.2 0.1 1.1 260.3 0.1 0.1 1.3 1.2 3.2 194.0 0.5 11.1 5.4 5.1 1.3 10.8 2.9 9.9 10.4 6.3 9.9 14.3 4.3 3.0 0.1 0.0 1.9 1.3 61.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 3.9 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.5 0.0 0.0 0.0 1.4 0.4 0.2 0.0 23.3 0.1 0.0 0.0 0.3 2.8 0.3 1.7 14.2 1.0 3.0 0.0 1.0 0.0 0.9 0.1 0.0 0.0 80.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.8 0.0 0.0 0.0 1.1 0.0 0.3 0.5 PNPLA7 "C9orf111, FLJ31318, FLJ43070, FLJ44279, NTE-R1, NTEL1, RP11-48C7.2" ENSG00000130653 "Patatin like phospholipase domain containing 7" Q6ZV29 9 137459952-137550402 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 56.2;Excitatory neurons: 23.6;Inhibitory neurons: 21.5;Oligodendrocytes: 21.0" "Cancer enhanced" "Detected in many" "prostate cancer: 9.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.0;T-reg: 1.2" "Group enriched" "Detected in many" 4 "B-cells: 1.0;T-cells: 1.2" "Cell line enriched" "Detected in some" 22 "HMC-1: 83.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009130 Uncertain Uncertain "Centriolar satellite,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 50: Non-specific - Ribosome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol "Centriolar satellite" "HPA009130: AB_2268411" "unprognostic (1.49e-1)" "unprognostic (1.40e-2)" "unprognostic (3.61e-3)" "unprognostic (2.38e-2)" "unprognostic (3.68e-2)" "unprognostic (6.69e-3)" "unprognostic (2.72e-3)" "unprognostic (5.14e-4)" "unprognostic (3.24e-1)" "unprognostic (1.40e-2)" "prognostic favorable (2.24e-5)" "unprognostic (1.09e-1)" "unprognostic (2.23e-3)" "unprognostic (2.42e-1)" "unprognostic (6.80e-2)" "unprognostic (8.81e-2)" "unprognostic (3.45e-3)" 9.6 7.0 5.2 2.2 5.3 2.1 11.3 1.9 8.6 17.6 1.2 10.8 2.2 12.3 1.0 2.7 13.0 3.7 6.9 6.6 2.6 6.3 14.0 4.7 4.4 4.6 2.6 21.5 17.9 2.0 8.9 0.6 3.6 22.5 1.4 1.3 15.9 2.7 17.3 14.3 8.4 1.6 2.2 7.0 16.3 2.6 4.2 1.4 17.3 3.4 1.4 10.5 7.6 5.9 0.1 1.0 0.2 0.3 0.8 0.5 0.4 0.8 0.8 0.2 0.2 0.1 0.5 0.6 0.8 0.4 0.4 0.3 0.1 0.0 0.0 1.6 0.9 0.8 1.0 0.3 0.5 0.4 83.7 1.2 0.1 0.3 0.0 1.4 0.1 0.1 0.1 2.3 0.1 1.6 0.2 1.6 0.0 1.2 0.9 2.0 1.3 2.8 0.1 0.3 1.6 0.4 0.1 0.6 0.3 0.2 3.7 1.2 0.6 0.0 0.1 0.4 0.1 0.8 0.2 0.2 1.2 0.8 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.1 0.1 0.2 1.0 0.3 0.2 0.0 0.0 0.0 0.1 1.2 0.2 5.2 5.3 1.9 8.6 6.6 2.6 4.6 2.6 3.6 2.2 4.2 5.9 3.0 9.6 5.9 56.2 4.8 1.5 1.1 0.9 2.2 2.5 6.5 8.3 3.9 4.3 2.6 1.8 6.2 0.2 2.1 6.6 0.0 0.7 0.5 1.7 4.8 1.2 17.3 0.8 23.6 0.0 0.3 3.6 12.2 3.8 7.0 1.2 2.5 10.2 2.6 5.0 21.5 9.2 0.0 4.5 1.0 0.6 4.4 1.2 0.0 9.4 1.3 2.5 1.0 11.6 21.0 0.6 7.1 1.9 1.6 2.5 3.8 1.0 1.6 9.6 0.0 2.3 2.1 3.1 4.0 0.9 3.3 0.0 2.3 0.6 2.0 0.7 PNPO PDXPO ENSG00000108439 "Pyridoxamine 5'-phosphate oxidase" Q9NVS9 17 47941506-47949308 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Pyridoxine biosynthesis" Oxidoreductase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 88.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 62.6;Hepatocytes: 53.4;Proximal tubular cells: 86.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023204, HPA027776" Enhanced Approved Nucleoplasm,Cytosol NA NA 450000 "Cluster 39: Non-specific - mRNA processing" "Cluster 15: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "HPA023204: AB_1855506, HPA027776: AB_10601246" "unprognostic (1.88e-2)" "unprognostic (1.17e-1)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "unprognostic (9.25e-2)" "unprognostic (2.39e-2)" "unprognostic (1.23e-2)" "unprognostic (1.41e-1)" "unprognostic (2.62e-1)" "unprognostic (1.97e-2)" "unprognostic (6.65e-2)" "unprognostic (8.34e-2)" "unprognostic (2.02e-3)" "unprognostic (7.47e-3)" "unprognostic (8.75e-2)" "unprognostic (3.34e-2)" "unprognostic (2.74e-1)" 7.3 15.8 16.5 6.2 15.9 3.5 10.6 16.7 22.0 7.0 12.9 8.8 10.2 5.0 11.6 10.7 10.1 6.6 13.2 16.0 21.9 35.1 88.8 6.4 6.9 19.1 21.2 5.8 10.9 26.6 9.2 7.0 20.6 8.0 8.6 5.4 10.4 7.8 21.1 6.7 9.6 6.1 16.5 7.2 8.6 6.6 20.6 5.8 17.8 19.6 7.7 6.7 7.3 14.3 37.9 30.9 2.4 5.8 15.3 11.7 0.0 12.2 7.7 14.0 11.9 51.1 27.6 35.2 57.4 12.7 5.5 22.0 19.4 34.7 20.3 43.4 16.4 24.6 13.9 53.6 16.3 22.6 16.6 15.4 26.9 25.8 32.7 13.1 18.0 26.1 24.4 12.2 16.5 28.3 25.3 7.8 4.5 37.4 37.1 18.8 10.4 26.2 40.2 19.5 12.1 9.5 11.2 18.6 10.7 8.5 32.4 9.1 19.1 22.6 12.8 22.2 26.2 27.8 34.0 19.0 18.4 19.2 11.7 2.5 12.3 2.8 7.2 17.7 8.2 6.7 6.3 7.6 13.5 5.3 8.2 8.1 1.1 7.9 11.9 9.8 7.0 10.3 16.5 15.9 16.7 22.0 16.0 21.9 19.1 21.2 20.6 16.5 20.6 14.3 7.6 12.8 13.9 7.5 3.9 1.5 6.7 5.0 5.7 1.1 16.2 14.4 1.9 18.6 6.8 12.9 4.2 8.4 7.8 7.3 62.6 18.2 0.8 11.2 6.4 5.9 3.6 7.4 4.2 15.6 1.9 5.3 4.6 13.3 12.7 8.8 6.4 53.4 17.2 3.3 6.2 11.6 2.0 11.4 2.4 0.9 9.9 10.6 1.8 2.8 8.6 7.1 3.1 2.5 3.2 15.0 8.9 6.0 4.9 9.0 20.2 86.3 5.9 1.9 0.0 4.1 3.8 0.7 1.3 7.2 2.3 6.3 4.7 19.5 15.4 5.0 PODN "MGC24995, PCAN, PODOCAN, SLRR5A" ENSG00000174348 Podocan Q7Z5L7 1 53062052-53085501 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 13 "Fibroblasts: 123.5;Leydig cells: 268.7;Peritubular cells: 261.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "gdT-cell: 5.1;memory CD8 T-cell: 1.4;naive CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 52 "T-cells: 5.1" "Cell line enhanced" "Detected in some" "ASC diff: 23.0;BJ: 39.2;fHDF/TERT166: 23.9;HHSteC: 94.1;U-2197: 46.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 910000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (8.69e-2)" "unprognostic (4.73e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (2.31e-1)" "unprognostic (1.88e-1)" "unprognostic (3.65e-1)" "unprognostic (1.90e-3)" "unprognostic (1.71e-1)" "unprognostic (3.53e-2)" "prognostic unfavorable (2.02e-5)" "unprognostic (5.91e-3)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (5.02e-2)" 191.0 14.3 9.1 13.3 8.2 0.2 116.3 6.4 8.7 106.1 7.1 76.1 11.6 105.1 19.7 36.1 127.5 103.8 87.1 6.8 8.1 5.2 12.5 66.3 3.8 7.3 10.3 178.0 20.8 2.9 19.5 18.1 8.2 69.8 8.2 0.6 48.8 34.4 20.2 45.4 26.1 44.7 6.7 3.3 75.5 26.9 10.3 10.8 71.5 30.5 2.7 101.3 87.9 6.7 0.0 0.0 0.0 0.0 23.0 3.1 0.1 39.2 5.3 0.4 0.3 0.0 0.0 0.0 0.6 23.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.1 0.0 0.0 14.9 0.0 0.9 0.0 1.0 1.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.1 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.0 0.0 46.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.3 1.4 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.8 9.1 8.2 6.4 8.7 6.8 8.1 7.3 10.3 8.2 6.7 10.3 6.7 8.5 0.0 3.3 0.0 0.0 6.4 0.4 0.0 0.6 0.5 0.8 0.9 1.7 1.5 0.6 0.0 0.0 0.4 1.3 0.0 0.0 0.0 1.6 0.3 11.2 3.8 0.0 0.0 0.0 0.0 0.4 123.5 2.6 0.3 0.0 0.7 4.2 0.1 0.6 0.0 1.9 0.0 0.0 0.3 8.8 9.2 268.7 1.3 5.4 6.5 0.0 0.3 3.1 5.5 0.2 0.0 0.0 261.1 1.6 0.5 0.1 0.0 0.0 0.5 0.0 4.4 16.0 0.7 0.6 0.7 6.0 0.5 1.6 0.0 0.0 0.2 PODXL "Gp200, PC, PCLP" ENSG00000128567 "Podocalyxin like" O00592 7 131500262-131558217 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 96.2" "Cell type enhanced" "Detected in many" "Adipocytes: 165.8;Cone photoreceptor cells: 87.6;Endothelial cells: 181.1;Glandular and luminal cells: 121.3;Microglial cells: 92.8;Rod photoreceptor cells: 188.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 295.8;NTERA-2: 509.7;SuSa: 640.8;TIME: 474.0;U-251 MG: 226.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002110, CAB016169, HPA045507, CAB062558, CAB068219, CAB068220" Enhanced Supported "Vesicles,Plasma membrane,Centriolar satellite" NA NA 33000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Centriolar satellite" Vesicles "CAB016169: AB_628165, CAB062558: AB_2665627, CAB068219: AB_2665618, CAB068220: AB_2665619, HPA002110: AB_1855512, HPA045507: AB_2679356" "unprognostic (1.26e-1)" "unprognostic (7.68e-2)" "unprognostic (8.28e-3)" "unprognostic (6.46e-3)" "unprognostic (5.16e-3)" "unprognostic (5.85e-2)" "unprognostic (1.63e-2)" "unprognostic (1.05e-1)" "unprognostic (7.95e-3)" "unprognostic (3.52e-1)" "unprognostic (9.20e-3)" "unprognostic (3.40e-1)" "prognostic favorable (2.89e-4)" "unprognostic (2.56e-1)" "unprognostic (8.78e-3)" "unprognostic (3.55e-2)" "unprognostic (1.03e-1)" 20.8 6.8 27.7 8.9 26.5 0.3 21.9 25.2 34.4 26.0 19.0 8.4 5.1 27.5 5.6 8.1 49.0 14.5 29.1 25.2 25.3 96.2 3.0 31.8 5.6 29.2 28.1 6.1 26.0 18.9 1.1 29.3 29.5 8.7 8.6 67.8 16.1 18.9 15.3 4.8 6.2 28.9 22.0 5.6 5.6 2.4 42.0 3.7 28.5 26.1 6.1 9.6 1.0 22.0 50.9 18.9 42.6 16.3 0.5 0.0 2.6 5.4 4.2 16.9 6.1 121.4 83.1 0.3 109.7 295.8 57.1 34.9 34.3 0.7 15.3 5.4 17.3 0.2 115.0 2.7 1.1 4.2 4.0 0.2 0.4 50.5 0.8 9.4 146.3 1.5 10.5 1.8 16.9 18.0 0.5 1.3 509.7 10.0 43.6 16.2 73.1 15.8 1.6 16.6 34.3 8.9 34.7 7.0 0.2 640.8 4.1 2.2 474.0 6.8 26.6 72.5 226.1 2.5 4.5 1.2 27.1 20.1 48.4 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.7 26.5 25.2 34.4 25.2 25.3 29.2 28.1 29.5 22.0 42.0 22.0 165.8 6.4 9.9 3.6 2.4 5.2 0.9 14.0 0.6 9.7 33.3 20.7 22.9 4.3 25.4 27.6 87.6 0.8 1.0 1.0 0.0 4.6 0.8 44.8 13.0 181.1 2.4 2.7 9.4 18.3 0.4 9.2 1.1 121.3 2.5 2.2 65.0 1.0 0.4 5.0 3.3 12.9 4.1 0.9 9.6 1.3 4.7 2.6 5.4 92.8 0.7 10.6 0.0 7.1 3.1 42.7 0.8 0.4 4.3 3.6 0.7 0.8 10.3 188.4 0.0 6.3 8.4 0.3 1.1 1.3 3.1 0.7 3.3 1.9 2.7 5.8 POF1B "FLJ22792, POF" ENSG00000124429 "POF1B actin binding protein" Q8WVV4 X 85277396-85379717 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 54.2;skin 1: 123.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 129.8;Gastric mucus-secreting cells: 48.9;Intestinal goblet cells: 61.1;Paneth cells: 62.5;Proximal enterocytes: 73.6;Squamous epithelial cells: 39.2;Undifferentiated cells: 51.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 44.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "memory B-cell: 2.9;naive B-cell: 2.1" "Lineage enriched" "Detected in single" 7 "B-cells: 2.9" "Group enriched" "Detected in some" 5 "OE19: 179.0;RT4: 78.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA002033, HPA050027" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA 200000 "Cluster 19: B-cells - Humoral immune response" "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Nucleoplasm "HPA002033: AB_1079650, HPA050027: " "unprognostic (2.23e-1)" "unprognostic (1.05e-1)" "unprognostic (2.54e-3)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.97e-1)" "unprognostic (3.39e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (1.86e-1)" "unprognostic (1.72e-1)" "unprognostic (1.30e-1)" "unprognostic (1.17e-2)" "unprognostic (2.50e-1)" "unprognostic (4.42e-2)" "unprognostic (1.07e-2)" "unprognostic (1.81e-1)" "unprognostic (5.57e-4)" "unprognostic (1.01e-2)" 0.7 0.3 0.1 6.1 0.1 0.2 11.0 0.8 0.3 6.4 0.0 54.2 34.4 0.2 0.5 33.1 6.2 9.0 10.6 0.1 0.0 1.4 0.4 1.8 0.5 0.0 0.0 0.1 6.9 0.0 0.3 1.0 0.0 2.9 50.9 0.4 8.5 1.3 0.8 123.9 43.4 2.0 0.0 3.5 23.7 0.2 0.0 0.5 0.5 0.0 12.0 14.3 14.7 0.0 3.7 22.9 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 12.5 23.9 12.0 3.3 0.0 0.1 23.7 5.1 0.4 0.0 2.4 0.1 4.4 0.1 0.1 0.0 0.1 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.3 0.7 3.9 0.0 9.6 0.1 0.2 0.0 179.0 0.0 0.2 1.0 0.1 0.0 78.2 0.1 0.1 0.0 6.0 0.0 1.8 2.4 1.0 0.2 0.1 0.1 0.2 0.3 2.0 4.8 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.2 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.8 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.7 1.2 9.1 4.9 7.9 12.0 0.0 2.5 0.8 24.2 8.6 10.2 5.5 0.0 3.2 0.0 129.8 0.0 13.8 0.0 0.3 0.0 1.7 22.8 0.0 0.4 15.6 0.6 3.4 48.9 0.2 0.0 0.0 0.4 0.2 0.3 0.0 0.4 61.1 6.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 0.4 24.8 62.5 0.0 0.2 3.9 73.6 0.1 9.5 0.0 0.0 0.1 0.9 0.0 0.1 39.2 28.6 5.3 0.3 0.0 51.1 17.1 POLR2H RPB8 ENSG00000163882 "RNA polymerase II, I and III subunit H" P52434 3 184361718-184368596 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037745, HPA055813" Supported Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA037745: AB_10672914, HPA055813: AB_2797254" "unprognostic (3.21e-1)" "unprognostic (4.96e-3)" "unprognostic (3.61e-3)" "unprognostic (7.15e-2)" "unprognostic (1.17e-2)" "unprognostic (6.72e-2)" "prognostic unfavorable (2.01e-4)" "unprognostic (8.82e-3)" "unprognostic (2.84e-1)" "unprognostic (4.02e-3)" "unprognostic (4.24e-2)" "unprognostic (1.27e-3)" "prognostic unfavorable (1.65e-10)" "unprognostic (1.34e-1)" "unprognostic (4.01e-1)" "unprognostic (1.71e-1)" "unprognostic (2.93e-3)" 41.6 60.6 50.4 32.5 51.0 31.1 42.2 53.5 60.1 48.8 51.8 54.4 57.6 36.3 39.7 52.1 39.8 30.0 34.8 50.7 49.9 77.5 63.8 37.6 41.1 50.8 50.6 40.2 52.1 35.5 32.9 34.9 50.9 42.9 57.8 14.6 44.2 26.3 37.3 37.8 55.5 35.0 49.8 41.9 51.2 32.3 51.3 39.8 48.3 30.0 40.8 43.4 41.5 52.9 225.2 77.3 81.7 121.4 89.0 62.8 101.2 82.8 86.3 110.8 141.6 199.6 104.6 126.0 201.7 65.0 168.4 88.8 147.4 148.7 98.1 124.4 194.7 121.4 89.8 126.2 80.1 129.3 67.9 81.6 83.3 72.6 129.8 99.4 116.3 124.6 95.3 81.0 89.0 265.6 128.7 172.3 89.0 279.0 159.3 74.3 74.9 171.2 133.9 100.3 122.8 87.3 69.7 214.0 126.9 78.6 267.9 102.4 61.5 52.5 82.9 70.9 224.3 161.7 181.3 237.3 83.4 136.2 71.5 8.3 17.6 15.9 26.8 30.7 32.9 32.9 31.6 29.1 34.0 33.9 45.8 34.8 1.3 29.8 19.2 34.7 36.7 21.6 50.4 51.0 53.5 60.1 50.7 49.9 50.8 50.6 50.9 49.8 51.3 52.9 45.1 38.5 43.8 23.8 39.4 113.4 74.1 113.7 61.5 22.0 70.1 77.0 17.4 47.1 70.2 44.1 16.7 103.2 45.8 132.8 140.8 73.0 21.0 62.3 62.3 57.9 55.7 53.8 12.9 91.2 146.0 52.8 53.5 83.7 31.1 50.4 43.2 58.5 61.4 25.2 15.8 80.2 93.6 21.4 57.5 14.3 46.0 29.9 51.6 9.4 29.0 26.7 32.0 8.5 11.5 97.6 90.9 27.8 52.1 139.7 94.5 150.5 55.1 24.9 39.5 48.0 69.6 92.9 111.0 66.0 74.2 122.3 38.0 71.6 83.1 92.5 POLR3B "C128, FLJ10388, RPC2" ENSG00000013503 "RNA polymerase III subunit B" Q9NW08 12 106357748-106510198 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Nucleotidyltransferase, Transferase" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 24.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036466 Supported Approved "Nuclear speckles" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA036466: AB_10671842" "unprognostic (1.17e-1)" "unprognostic (1.52e-1)" "unprognostic (4.80e-2)" "unprognostic (1.37e-2)" "unprognostic (1.13e-1)" "unprognostic (2.73e-1)" "unprognostic (4.21e-2)" "unprognostic (1.12e-1)" "unprognostic (1.33e-1)" "unprognostic (3.36e-2)" "unprognostic (6.11e-2)" "unprognostic (5.09e-2)" "prognostic favorable (1.21e-4)" "unprognostic (1.54e-1)" "unprognostic (1.46e-1)" "unprognostic (8.73e-2)" "unprognostic (9.24e-2)" 4.5 8.7 3.1 4.8 4.4 5.2 5.0 4.3 4.6 4.7 3.7 5.3 4.2 4.6 5.2 8.6 5.1 3.6 5.8 3.4 2.9 6.8 9.0 4.7 4.1 2.2 2.3 7.5 4.9 11.1 2.4 6.7 2.3 5.6 5.7 6.2 4.7 4.0 6.5 11.0 3.4 5.4 2.7 3.3 5.4 6.1 3.2 4.7 6.0 8.3 5.6 4.9 4.3 3.6 16.2 7.6 16.4 7.8 13.9 13.1 22.9 21.9 13.0 15.2 11.6 14.0 4.4 20.6 7.7 14.2 5.6 14.8 19.5 19.2 18.5 16.6 13.1 15.7 10.1 12.0 9.2 26.1 17.0 11.7 13.4 15.1 17.3 10.3 11.5 9.8 24.5 6.5 11.2 12.0 19.1 8.7 17.8 11.9 28.5 11.6 9.8 13.5 8.6 21.8 17.3 9.6 13.6 18.2 13.4 10.8 17.0 7.9 11.0 8.3 10.0 13.6 13.1 8.1 22.4 30.3 3.8 15.9 9.2 5.6 2.0 1.5 2.0 2.2 2.7 2.1 2.2 2.2 2.6 1.3 3.0 1.9 1.3 2.1 2.2 0.9 2.7 1.7 3.1 4.4 4.3 4.6 3.4 2.9 2.2 2.3 2.3 2.7 3.2 3.6 2.4 0.0 9.2 14.4 4.7 1.8 1.7 4.5 4.6 6.0 3.4 3.7 10.3 2.8 7.0 5.5 6.2 11.0 3.8 3.8 1.9 5.1 7.1 3.9 7.0 3.3 4.2 3.8 22.3 4.6 9.3 4.4 9.2 3.9 5.1 4.8 3.6 11.0 3.1 3.3 24.1 5.6 2.0 1.6 0.3 5.2 3.7 2.4 3.6 9.4 1.0 2.4 2.1 17.1 22.4 3.8 1.1 4.9 4.9 1.5 1.7 3.4 7.2 7.2 6.6 6.9 4.1 16.5 10.9 8.9 3.0 7.4 4.1 7.2 5.1 1.2 POU6F2 RPF-1 ENSG00000106536 "POU class 6 homeobox 2" P78424 7 38977909-39493095 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.0" "Group enriched" "Detected in some" 5 "Astrocytes: 129.3;Excitatory neurons: 471.3;Oligodendrocyte precursor cells: 286.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.2;Karpas-707: 1.3;NTERA-2: 2.6;SK-BR-3: 1.1;SuSa: 1.5;T-47d: 2.9;U-266/70: 2.2;U-266/84: 1.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" NA NA "Cluster 65: Brain - Ion transport" "Cluster 6: T47d - Mammary gland" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (6.89e-2)" "unprognostic (1.04e-1)" "unprognostic (2.48e-1)" "unprognostic (1.80e-4)" "unprognostic (1.26e-1)" "unprognostic (1.16e-1)" "unprognostic (8.68e-2)" "unprognostic (3.36e-1)" "unprognostic (1.01e-1)" "unprognostic (1.96e-1)" "unprognostic (7.22e-3)" "unprognostic (2.32e-1)" "unprognostic (1.60e-2)" "unprognostic (5.00e-3)" "unprognostic (4.46e-2)" "unprognostic (1.03e-1)" "unprognostic (1.99e-1)" 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.1 1.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.9 0.5 0.0 0.4 0.0 0.0 0.2 0.6 0.1 0.8 0.0 0.1 0.6 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.7 0.1 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.3 0.0 0.0 0.0 0.0 2.6 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.1 0.0 1.5 2.9 0.0 0.0 0.0 0.2 0.0 0.0 2.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.1 1.4 0.9 0.5 0.2 0.6 0.3 0.1 0.3 2.0 0.0 0.0 1.7 129.3 0.0 0.0 0.3 0.0 0.0 4.9 0.0 0.0 2.1 8.6 0.0 0.0 8.4 0.3 0.0 0.2 0.0 1.5 4.1 0.0 0.0 0.4 0.0 0.0 471.3 0.0 0.3 0.7 0.0 0.0 1.3 0.0 0.0 3.5 0.1 0.0 50.3 0.1 0.0 0.0 0.2 4.1 0.0 0.0 0.0 26.2 0.0 0.1 0.0 286.5 5.9 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.4 0.3 2.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 PPA2 FLJ20459 ENSG00000138777 "Inorganic pyrophosphatase 2" Q9H2U2 4 105369077-105474067 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030888, HPA031671, HPA031672" Supported Approved Mitochondria NA NA 150000 "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA030888: AB_2673646, HPA031671: AB_10603986, HPA031672: AB_2673988" "prognostic unfavorable (2.98e-4)" "unprognostic (5.64e-2)" "prognostic favorable (6.60e-4)" "unprognostic (9.26e-3)" "unprognostic (2.93e-2)" "unprognostic (5.10e-2)" "unprognostic (1.15e-1)" "unprognostic (2.44e-1)" "unprognostic (1.50e-1)" "unprognostic (1.20e-1)" "unprognostic (7.05e-2)" "unprognostic (9.54e-2)" "prognostic favorable (1.27e-11)" "unprognostic (3.69e-1)" "unprognostic (1.94e-1)" "unprognostic (2.00e-1)" "unprognostic (1.10e-1)" 7.4 12.8 23.8 9.0 24.6 22.0 12.0 24.3 53.7 7.4 29.5 17.4 14.2 7.4 12.5 10.8 8.4 8.0 27.5 23.7 26.3 20.7 14.8 7.5 8.3 24.4 24.3 5.8 11.8 11.7 7.7 7.4 24.5 13.3 14.0 13.6 13.8 5.7 27.6 12.2 13.8 6.8 24.0 9.9 12.6 6.3 25.4 7.0 11.5 35.5 8.7 8.1 6.7 26.6 20.6 8.5 18.5 32.3 11.3 9.1 12.9 10.2 15.7 14.6 9.9 22.2 30.4 15.6 14.5 9.7 11.3 9.5 39.2 18.7 17.0 23.6 11.8 13.5 13.7 19.9 9.3 36.7 13.6 9.7 19.6 9.9 7.9 15.4 14.6 28.4 22.3 22.0 12.5 26.2 32.5 26.6 13.9 42.4 28.3 28.2 10.9 17.9 49.7 14.7 17.8 10.7 7.8 48.9 19.0 10.7 24.8 32.1 6.9 9.2 19.2 8.9 20.0 19.0 27.3 18.4 17.5 18.6 14.1 27.0 20.9 15.4 21.0 30.1 18.6 28.5 21.7 23.7 49.9 22.6 21.1 23.9 9.5 36.4 26.4 25.9 23.4 23.5 23.8 24.6 24.3 53.7 23.7 26.3 24.4 24.3 24.5 24.0 25.4 26.6 26.7 9.6 67.3 86.2 37.6 50.0 82.4 205.0 38.1 29.7 64.8 40.9 63.3 45.8 126.2 33.1 16.7 119.0 25.9 73.3 264.1 114.0 113.7 42.3 35.3 36.3 65.7 70.2 138.2 120.1 98.5 31.1 37.2 42.3 45.6 26.4 24.3 64.2 83.5 21.9 134.6 104.6 142.4 42.9 86.1 126.4 27.7 47.1 76.5 74.9 50.5 39.2 30.9 169.9 145.7 65.0 90.4 32.4 41.9 68.1 112.2 285.4 90.7 22.6 39.5 46.3 43.6 50.8 10.8 59.1 57.7 84.7 34.3 72.1 138.0 94.6 PPID CYP-40 ENSG00000171497 "Peptidylprolyl isomerase D" Q08752 4 158709127-158723396 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Protein transport, Transport" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019520, HPA019692" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA 480000 "Cluster 2: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 10: Non-specific - Unknown function" Cytosol "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA019520: AB_1847400, HPA019692: AB_1847401" "unprognostic (4.26e-2)" "unprognostic (2.03e-2)" "unprognostic (8.91e-3)" "unprognostic (8.17e-3)" "unprognostic (1.50e-1)" "unprognostic (2.04e-3)" "unprognostic (4.72e-2)" "unprognostic (1.62e-2)" "unprognostic (4.72e-2)" "unprognostic (5.92e-2)" "unprognostic (4.54e-2)" "unprognostic (1.46e-2)" "unprognostic (2.66e-3)" "unprognostic (8.78e-2)" "unprognostic (1.74e-1)" "unprognostic (1.64e-1)" "unprognostic (1.09e-1)" 26.8 38.3 38.0 24.4 40.2 25.1 22.8 40.4 77.6 25.4 46.4 33.9 50.6 24.2 19.0 27.7 24.1 18.8 49.6 40.1 44.2 39.5 87.6 19.8 28.6 39.0 39.4 24.2 31.7 17.0 28.6 21.6 40.2 23.5 20.3 36.2 23.3 18.7 88.9 36.1 45.3 18.9 39.6 29.1 29.0 24.1 42.2 24.3 23.9 45.5 25.8 27.4 24.0 46.9 46.7 42.3 41.8 57.7 60.7 45.2 63.1 44.9 24.3 40.3 30.4 55.4 30.9 48.9 19.7 42.0 63.4 35.1 127.9 51.5 48.8 162.9 44.4 87.5 36.5 76.9 46.8 55.6 63.0 28.9 41.2 34.6 51.5 52.0 44.6 81.9 111.0 84.4 45.5 44.6 80.0 49.9 57.9 75.5 55.8 35.9 20.7 41.7 44.6 23.0 70.2 47.1 33.8 69.2 65.6 60.0 31.9 52.2 43.7 40.1 45.3 44.7 60.2 48.3 107.2 62.0 51.1 59.4 41.1 68.8 23.9 55.2 31.1 35.4 36.0 22.3 30.2 29.1 26.4 25.4 30.9 32.0 32.9 40.5 37.7 26.9 37.0 28.0 38.0 40.2 40.4 77.6 40.1 44.2 39.0 39.4 40.2 39.6 42.2 46.9 29.2 6.4 13.4 13.1 24.8 10.1 29.7 17.5 9.1 30.2 19.1 20.8 59.7 25.8 27.9 27.6 22.9 41.5 38.7 17.1 37.2 39.2 39.0 66.1 39.9 25.1 19.6 17.4 24.3 23.0 49.5 24.3 14.3 28.5 32.3 24.4 17.2 18.5 41.9 75.7 28.6 28.3 22.4 17.0 14.7 23.1 20.5 26.0 14.2 9.4 51.6 23.3 48.4 15.1 28.3 29.5 27.4 22.6 22.3 31.6 39.7 33.7 62.3 32.3 6.6 17.7 58.2 96.0 77.5 16.9 11.8 47.6 33.7 33.7 32.0 20.2 PPM1F "CAMKP, CaMKPase, FEM-2, KIAA0015, POPX2" ENSG00000100034 "Protein phosphatase, Mg2+/Mn2+ dependent 1F" P49593 22 21919425-21952848 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endothelial cells: 42.2;Hepatic stellate cells: 56.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 28.6" "Group enriched" "Detected in all" 7 "dendritic cells: 8.9;granulocytes: 28.6;monocytes: 24.4" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 109.1;K-562: 173.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030989, HPA030990" Approved Approved "Nucleoplasm,Plasma membrane" NA NA 510000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Plasma membrane" "HPA030989: AB_10669549, HPA030990: AB_10601249" "unprognostic (6.26e-2)" "unprognostic (2.50e-1)" "unprognostic (1.82e-1)" "unprognostic (2.11e-1)" "unprognostic (2.51e-1)" "unprognostic (4.77e-3)" "unprognostic (4.88e-3)" "unprognostic (1.94e-1)" "unprognostic (1.70e-1)" "unprognostic (1.65e-2)" "unprognostic (1.45e-2)" "unprognostic (4.81e-2)" "prognostic unfavorable (6.03e-5)" "unprognostic (6.44e-2)" "unprognostic (3.02e-2)" "unprognostic (3.30e-1)" "unprognostic (4.11e-2)" 24.1 18.1 14.9 21.6 13.9 26.8 17.6 11.6 15.7 18.5 11.8 17.1 8.9 19.9 3.8 22.1 15.0 12.2 16.8 14.5 19.4 18.4 8.0 26.1 15.2 16.8 16.4 12.5 12.3 6.4 8.5 26.6 17.3 15.8 4.2 3.7 10.9 14.3 17.0 14.8 13.8 12.1 15.3 35.8 12.0 6.3 17.1 7.8 12.4 10.5 7.8 22.0 15.9 15.4 28.9 30.1 19.0 18.6 10.4 18.1 23.9 32.1 18.9 27.7 19.0 13.8 11.3 17.3 39.0 22.7 11.8 33.9 8.3 19.9 9.8 24.7 27.1 66.8 14.5 13.2 17.1 25.0 17.4 17.1 5.9 27.1 12.6 19.6 109.1 16.9 173.4 7.2 35.9 26.2 15.0 19.3 8.0 9.2 32.7 21.9 49.0 5.2 9.4 12.1 7.7 29.6 30.4 10.0 25.7 7.4 12.5 17.2 93.1 33.1 33.4 30.5 31.1 14.1 12.2 19.6 33.5 46.7 64.7 0.0 12.8 5.9 1.7 21.0 1.0 1.1 1.1 0.9 8.9 0.9 1.0 1.3 28.6 3.1 24.4 2.2 2.4 5.4 14.9 13.9 11.6 15.7 14.5 19.4 16.8 16.4 17.3 15.3 17.1 15.4 32.1 6.4 6.0 11.8 5.5 8.2 5.2 4.9 8.6 8.3 7.4 9.9 11.9 8.6 4.1 1.8 2.1 16.6 5.1 1.4 3.9 5.2 2.0 3.0 9.4 42.2 6.0 5.5 11.6 5.1 10.0 8.4 3.1 3.8 3.8 10.4 56.4 6.5 20.6 8.4 12.7 4.2 6.1 37.0 22.0 1.5 7.2 23.4 7.2 18.7 30.9 4.1 6.2 12.5 6.8 7.4 1.1 6.8 5.0 7.4 2.6 4.4 4.0 6.5 6.6 17.2 8.2 14.2 13.1 8.5 5.7 3.0 6.4 7.1 4.5 6.6 PPP1R12B "MGC131980, MGC87886, MYPT2, PP1bp55" ENSG00000077157 "Protein phosphatase 1 regulatory subunit 12B" O60237 1 202348699-202592706 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 356.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 836.8;Excitatory neurons: 225.7;Granulosa cells: 438.3;Oligodendrocytes: 647.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 16.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 16.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024171, HPA024640" Enhanced Approved "Plasma membrane,Actin filaments" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Actin filaments" "HPA024171: AB_1854266, HPA024640: AB_1854265" "unprognostic (5.24e-2)" "unprognostic (8.59e-2)" "unprognostic (1.38e-1)" "unprognostic (2.75e-2)" "unprognostic (3.04e-1)" "unprognostic (5.45e-3)" "unprognostic (3.12e-2)" "unprognostic (9.13e-3)" "unprognostic (4.05e-2)" "unprognostic (3.74e-2)" "unprognostic (2.79e-2)" "unprognostic (1.80e-1)" "unprognostic (3.60e-3)" "unprognostic (6.98e-3)" "unprognostic (1.27e-1)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" 40.0 11.1 5.1 36.0 12.6 8.3 17.8 8.9 9.9 51.8 15.5 151.0 24.1 222.0 30.5 150.1 52.6 72.5 356.9 5.5 6.5 14.3 8.4 24.8 18.6 17.2 15.3 38.3 7.2 6.2 5.0 34.4 18.0 142.8 64.8 7.6 20.0 198.6 84.1 11.0 30.9 246.4 16.2 30.8 41.5 7.1 9.2 7.7 10.9 80.5 15.1 86.7 23.0 27.3 2.2 4.4 3.3 3.2 4.6 3.3 5.4 1.7 1.7 1.8 1.7 1.9 3.9 2.5 0.8 3.2 4.3 7.0 5.0 2.7 1.9 3.3 3.1 2.5 7.1 1.2 1.1 5.4 2.8 2.6 3.0 2.5 2.6 9.1 1.5 2.8 3.9 2.9 3.1 1.7 4.1 3.4 2.3 2.4 0.9 2.6 8.5 3.7 1.4 8.1 4.0 3.1 3.3 3.9 1.9 4.4 3.4 2.4 1.9 2.5 1.5 1.9 1.5 4.2 4.3 2.7 2.4 4.4 10.2 2.4 1.7 1.5 1.6 1.0 1.4 2.0 1.1 1.0 1.5 2.1 1.3 1.0 16.2 0.7 1.5 1.7 1.7 0.5 5.1 12.6 8.9 9.9 5.5 6.5 17.2 15.3 18.0 16.2 9.2 27.3 12.5 12.8 19.8 181.5 6.0 17.3 49.0 35.6 8.6 59.3 11.1 20.6 836.8 11.5 23.0 12.9 75.0 18.1 8.6 52.9 11.7 10.1 39.2 19.3 16.1 15.2 24.0 5.2 225.7 12.9 8.4 51.4 17.3 7.6 18.9 438.3 16.4 9.6 9.4 26.9 205.0 17.2 63.1 23.5 10.9 13.1 12.2 8.2 8.8 102.1 7.8 10.2 5.2 102.5 647.4 6.3 21.1 51.1 9.6 24.3 12.8 7.1 27.4 30.4 32.9 38.6 162.7 19.3 13.9 7.1 10.9 25.4 10.7 14.2 33.9 28.4 PPP1R1A ENSG00000135447 "Protein phosphatase 1 regulatory inhibitor subunit 1A" Q13522 12 54575387-54588659 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 259.7;skeletal muscle: 831.6;tongue: 271.1" "Cell type enriched" "Detected in many" 4 "Distal tubular cells: 1348.0" "Cancer enhanced" "Detected in many" "liver cancer: 17.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 8.8;NTERA-2: 29.4;RPTEC TERT1: 32.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007811, HPA041542" Approved NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "CAB007811: AB_598171, HPA041542: AB_2677542" "unprognostic (6.39e-3)" "unprognostic (2.61e-1)" "unprognostic (4.61e-3)" "prognostic unfavorable (2.36e-5)" "unprognostic (1.55e-1)" "unprognostic (1.85e-1)" "unprognostic (8.19e-3)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (7.04e-2)" "unprognostic (2.71e-3)" "unprognostic (1.76e-3)" "unprognostic (2.88e-3)" "unprognostic (7.68e-3)" "unprognostic (2.17e-1)" "unprognostic (8.49e-3)" "unprognostic (7.49e-2)" 241.3 2.6 37.1 1.1 73.6 0.3 169.8 26.1 45.7 1.6 20.4 29.6 3.0 2.2 0.7 10.3 3.8 1.5 110.9 38.9 36.9 259.7 138.1 1.0 0.5 29.0 32.0 7.7 14.2 20.8 1.8 0.0 26.0 7.9 1.8 14.6 9.7 3.2 831.6 7.6 13.2 3.3 25.5 0.5 27.8 2.2 31.6 0.2 2.6 271.1 0.5 5.4 1.5 34.1 0.0 0.0 3.9 0.0 8.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 5.4 0.0 0.0 0.1 2.1 0.1 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 29.4 0.0 0.0 0.0 0.0 0.2 32.6 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.3 0.0 0.0 1.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.1 73.6 26.1 45.7 38.9 36.9 29.0 32.0 26.0 25.5 31.6 34.1 7.9 0.0 0.0 3.3 3.4 0.1 0.0 0.0 0.0 2.2 23.7 40.6 300.7 5.7 0.0 18.4 0.0 0.0 0.5 0.0 1348.0 3.5 1.6 10.4 0.5 4.6 2.4 2.7 3.1 0.4 0.1 24.5 0.0 13.8 0.0 21.0 6.4 218.4 0.6 112.7 1.8 2.1 0.0 3.8 0.0 1.9 1.2 1.6 0.0 0.0 0.0 3.7 0.0 0.0 0.5 2.5 0.1 1.2 0.0 0.3 0.5 156.8 0.0 2.8 0.0 19.2 21.6 0.2 5.9 0.0 0.3 0.0 0.9 4.2 2.0 0.2 PPP1R9B "PPP1R6, PPP1R9, SPINO, Spn" ENSG00000108819 "Protein phosphatase 1 regulatory subunit 9B" Q96SB3 17 50133737-50150677 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 96.7" "Cell type enhanced" "Detected in many" "Kupffer cells: 48.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022461 Approved NA NA 420000000 "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" "CAB022461: " "unprognostic (4.71e-1)" "unprognostic (3.77e-2)" "unprognostic (3.82e-2)" "unprognostic (1.23e-1)" "unprognostic (2.02e-1)" "unprognostic (2.17e-1)" "unprognostic (1.74e-3)" "unprognostic (1.99e-1)" "unprognostic (4.09e-2)" "unprognostic (2.80e-1)" "prognostic favorable (3.11e-4)" "unprognostic (8.50e-2)" "unprognostic (1.57e-2)" "unprognostic (1.49e-2)" "unprognostic (4.17e-2)" "unprognostic (1.71e-2)" "unprognostic (4.29e-1)" 23.5 30.0 61.4 28.6 58.6 33.7 20.2 39.3 96.7 25.4 4.6 17.6 14.9 22.0 8.4 28.9 19.6 15.5 24.3 90.2 30.3 23.3 11.9 39.9 36.8 25.7 40.1 27.8 18.3 15.2 20.6 14.6 24.0 21.5 8.9 7.9 17.6 10.6 11.8 24.2 30.2 11.8 22.2 52.4 17.8 24.0 47.7 22.5 22.0 14.8 28.0 20.4 22.6 48.9 25.9 45.2 24.0 60.5 31.2 19.8 56.9 36.4 33.1 31.5 22.9 38.3 19.9 48.6 57.8 42.2 30.7 25.2 24.9 25.8 19.6 125.7 37.2 79.9 35.4 26.2 30.3 35.1 121.2 22.2 44.4 34.6 21.7 60.5 31.2 15.4 43.0 35.7 21.0 47.7 13.0 50.2 9.4 33.0 40.9 26.5 32.5 34.6 21.6 15.0 15.1 44.5 23.0 35.6 29.5 19.3 47.7 68.8 25.5 66.4 48.7 46.0 48.8 65.4 16.2 35.2 30.5 34.8 32.4 4.2 1.8 2.9 1.3 1.6 1.1 1.6 1.0 0.9 1.4 2.0 0.4 0.9 4.1 2.2 2.0 2.0 0.5 0.8 61.4 58.6 39.3 96.7 90.2 30.3 25.7 40.1 24.0 22.2 47.7 48.9 18.1 0.0 2.2 6.2 23.6 23.6 3.6 5.8 13.6 18.8 7.8 5.3 7.7 4.3 3.2 16.5 2.1 2.3 29.0 10.9 5.9 9.7 2.6 4.0 9.5 20.9 12.0 20.2 6.6 9.1 3.5 10.5 5.6 6.3 2.5 9.6 18.2 8.7 27.7 16.8 6.5 10.8 10.2 48.6 34.6 5.1 20.2 30.2 12.4 2.8 42.1 3.2 34.0 2.5 2.7 9.1 10.2 15.4 15.4 7.8 18.1 9.8 3.4 2.6 13.1 7.0 9.1 5.5 5.7 16.9 22.4 1.0 14.9 10.0 10.7 5.4 PPP2R5A "B56A, B56alpha, PR61A" ENSG00000066027 "Protein phosphatase 2 regulatory subunit B'alpha" Q15172 1 212285410-212361853 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 252.7;Late spermatids: 547.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059288, HPA078841" Approved Supported Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA059288: AB_2683966, HPA078841: " "unprognostic (3.56e-1)" "unprognostic (2.71e-1)" "unprognostic (8.48e-2)" "unprognostic (2.54e-1)" "unprognostic (9.21e-2)" "unprognostic (1.01e-1)" "unprognostic (5.01e-2)" "unprognostic (1.12e-2)" "unprognostic (8.07e-2)" "unprognostic (1.84e-2)" "unprognostic (3.04e-1)" "unprognostic (5.63e-2)" "unprognostic (1.40e-3)" "unprognostic (8.33e-2)" "unprognostic (1.42e-1)" "unprognostic (2.17e-1)" "unprognostic (1.39e-1)" 60.2 12.0 35.5 20.0 40.6 86.5 38.3 34.4 34.9 24.7 27.4 34.2 25.7 20.1 18.4 51.3 19.2 27.7 50.4 31.0 35.6 35.6 51.6 57.7 31.0 36.3 40.8 15.3 36.9 23.5 13.2 35.9 36.1 22.6 37.0 23.9 36.3 22.2 36.7 30.8 33.4 22.2 35.0 49.5 44.5 17.4 42.6 36.3 41.8 56.6 31.3 34.7 30.2 39.6 45.4 19.1 9.5 19.1 102.5 62.2 76.1 19.6 38.3 21.9 20.6 57.1 45.7 31.9 14.5 31.5 22.9 32.0 18.3 27.9 22.8 27.5 23.1 20.7 19.9 20.8 33.1 43.3 30.7 25.7 36.4 20.1 29.0 27.7 53.3 28.0 29.6 33.4 12.1 19.7 17.1 28.5 16.0 40.6 39.5 22.0 15.2 40.6 38.5 20.9 13.6 9.1 27.3 84.7 65.0 40.0 52.7 38.0 11.4 15.3 15.6 24.2 21.2 50.9 42.7 42.1 18.4 32.6 11.5 18.0 2.0 10.1 4.4 2.3 3.0 1.4 3.4 4.0 1.4 2.2 2.0 4.0 9.8 3.3 3.3 1.5 5.2 1.4 35.5 40.6 34.4 34.9 31.0 35.6 36.3 40.8 36.1 35.0 42.6 39.6 66.7 99.3 104.4 71.5 34.2 68.6 22.1 9.0 40.9 24.6 30.1 18.5 65.8 47.1 17.4 14.7 2.1 10.9 56.2 51.2 97.8 25.9 252.7 25.5 17.7 53.3 16.2 22.9 21.3 34.8 26.9 18.7 43.8 53.5 40.0 6.6 38.6 52.2 22.1 52.2 13.8 33.9 8.2 34.8 20.6 547.2 19.3 34.1 17.8 45.0 35.1 37.4 53.5 32.6 115.2 27.8 32.5 14.3 29.6 31.0 30.8 20.9 21.3 11.1 32.9 14.8 36.5 18.4 10.9 66.2 81.3 8.2 54.1 58.3 30.8 45.7 PPP4R3B "FLFL2, FLJ31474, KIAA1387, PSY2, SMEK2" ENSG00000275052 "Protein phosphatase 4 regulatory subunit 3B" Q5MIZ7 2 55547292-55618880 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001233, CAB017185" Approved Supported "Nucleoplasm,Nuclear speckles,Centrosome" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" Centrosome "CAB017185: , HPA001233: AB_1080033" "unprognostic (9.60e-2)" "unprognostic (2.47e-2)" "unprognostic (5.77e-2)" "unprognostic (1.87e-2)" "unprognostic (6.34e-2)" "unprognostic (3.56e-1)" "unprognostic (2.66e-2)" "unprognostic (3.27e-2)" "unprognostic (8.27e-3)" "unprognostic (7.62e-2)" "unprognostic (1.07e-2)" "unprognostic (3.69e-1)" "prognostic unfavorable (6.03e-4)" "unprognostic (9.73e-2)" "unprognostic (1.45e-1)" "unprognostic (6.28e-2)" "unprognostic (2.77e-1)" 29.0 27.4 14.8 28.2 15.1 25.8 29.1 20.9 16.9 26.8 20.0 28.1 31.6 23.7 19.3 31.7 32.3 24.7 14.3 13.8 16.9 33.4 48.0 23.4 38.1 15.0 16.3 25.7 32.1 27.4 12.5 24.5 16.2 24.9 27.7 35.3 28.1 23.2 14.7 29.6 32.1 21.8 15.9 28.7 30.8 23.7 15.1 42.2 33.0 20.3 38.7 26.7 16.9 18.7 42.8 33.0 35.6 30.0 37.2 38.9 49.1 34.0 35.9 28.2 24.0 39.5 40.9 57.7 67.5 32.7 44.8 36.4 39.9 27.5 41.4 84.6 16.7 56.7 30.0 52.9 60.3 66.0 45.6 29.8 64.9 34.1 60.1 36.9 45.0 31.6 55.2 57.4 37.7 50.9 42.8 43.7 35.1 55.9 25.3 40.1 53.6 44.6 39.3 43.8 43.4 26.9 36.8 49.9 54.8 23.5 31.6 52.0 36.3 43.3 56.8 21.6 47.2 59.1 47.3 22.3 40.8 61.3 47.2 25.6 16.5 26.9 20.4 20.9 23.2 18.1 21.2 21.6 18.4 18.6 24.5 21.5 19.6 22.5 23.0 9.9 24.0 23.9 14.8 15.1 20.9 16.9 13.8 16.9 15.0 16.3 16.2 15.9 15.1 18.7 46.8 44.8 41.3 0.0 61.8 0.0 48.9 0.0 44.3 44.1 42.7 27.9 0.0 31.5 29.1 16.5 33.3 30.6 51.4 25.3 39.2 32.4 9.5 85.1 43.2 32.9 18.2 46.7 0.0 41.0 28.5 33.9 43.8 39.6 30.3 39.0 26.0 52.5 26.2 53.8 0.0 29.4 0.0 37.7 0.0 7.6 28.0 44.9 0.0 0.0 47.9 53.1 49.4 0.0 0.0 35.4 24.1 36.1 57.2 57.4 46.1 52.9 62.7 38.5 6.6 54.9 28.4 39.1 25.7 53.3 0.0 47.7 56.3 44.6 29.0 57.2 PRDX2 "MGC4104, NKEFB, PRP, PRX2, PRXII, TDPX1, TSA" ENSG00000167815 "Peroxiredoxin 2" P32119 19 12796820-12801800 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1316.7;Erythroid cells: 3153.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB008713 Approved NA NA 800000000 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 6: Erythroid cells - Oxygen transport" "CAB008713: AB_1620974" "unprognostic (1.12e-1)" "unprognostic (1.98e-3)" "unprognostic (8.58e-2)" "unprognostic (4.40e-2)" "unprognostic (4.56e-2)" "unprognostic (1.92e-2)" "unprognostic (2.44e-1)" "unprognostic (2.59e-2)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (3.26e-2)" "unprognostic (9.18e-2)" "prognostic favorable (5.66e-11)" "unprognostic (7.01e-3)" "unprognostic (2.15e-1)" "unprognostic (3.51e-2)" "unprognostic (1.41e-1)" 199.0 622.0 350.8 88.3 366.6 686.7 159.7 408.2 461.5 167.8 365.6 208.1 251.7 178.8 144.5 271.8 153.5 133.9 704.0 369.6 400.0 287.7 310.2 109.1 118.3 407.5 380.4 218.2 201.7 454.5 314.6 87.8 408.2 175.3 141.5 207.1 200.1 124.4 722.9 260.7 201.1 127.0 357.0 118.1 226.6 32.8 399.1 181.3 156.3 847.9 129.2 163.6 171.6 355.5 420.4 1.1 553.9 721.3 79.5 54.2 408.4 189.0 188.0 253.9 143.4 438.1 102.8 122.7 430.9 185.0 30.2 389.5 354.7 309.7 72.9 528.5 561.4 222.6 537.4 665.1 212.4 0.7 1.4 233.6 140.5 191.1 93.0 327.6 238.8 255.3 485.7 187.0 98.7 763.3 500.1 190.2 409.1 289.6 789.4 485.8 0.7 593.0 343.1 450.0 683.8 538.5 449.5 454.9 153.7 100.7 408.0 318.0 105.7 188.2 156.9 526.7 417.7 226.3 242.1 573.5 178.9 75.5 43.8 35.4 170.0 85.6 436.1 129.4 460.6 375.2 589.8 446.2 211.6 288.5 594.7 460.9 22.4 213.2 148.0 124.5 697.4 686.6 350.8 366.6 408.2 461.5 369.6 400.0 407.5 380.4 408.2 357.0 399.1 355.5 192.2 22.4 36.7 39.5 117.5 221.3 255.6 877.7 187.2 317.9 271.2 322.2 37.1 265.9 347.7 279.6 100.1 692.8 83.5 367.4 1316.7 329.5 3.1 138.6 218.5 130.3 333.7 3153.4 31.8 167.2 558.8 204.3 214.6 197.7 47.0 466.0 137.8 489.7 234.0 215.4 50.8 360.7 754.8 63.8 128.8 13.0 293.9 58.7 281.1 23.4 61.4 531.2 56.7 41.7 29.1 179.6 250.6 321.2 263.4 169.3 765.6 1097.9 152.7 373.2 157.8 142.4 273.2 4.8 7.7 368.5 229.4 508.4 144.4 816.6 475.7 243.1 PRDX3 "AOP-1, AOP1, MER5, SP-22" ENSG00000165672 "Peroxiredoxin 3" P30048 10 119167720-119178812 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1060.4;Proximal tubular cells: 937.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008656, HPA041488, CAB079909" Enhanced Supported Mitochondria NA NA 1600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB008656: AB_1620979, CAB079909: AB_2809998, HPA041488: AB_2677508" "unprognostic (8.29e-2)" "unprognostic (1.02e-1)" "unprognostic (1.26e-2)" "unprognostic (1.68e-1)" "unprognostic (1.17e-1)" "unprognostic (1.72e-3)" "unprognostic (4.62e-3)" "unprognostic (2.40e-1)" "unprognostic (2.06e-1)" "unprognostic (3.65e-2)" "unprognostic (1.29e-2)" "unprognostic (9.48e-2)" "unprognostic (6.03e-3)" "unprognostic (2.77e-1)" "unprognostic (2.77e-1)" "unprognostic (2.27e-1)" "unprognostic (1.21e-1)" 165.7 335.3 92.4 96.0 92.6 82.3 138.3 101.3 116.0 103.4 139.2 133.3 137.8 87.0 120.8 83.3 116.7 88.0 278.2 95.2 104.5 385.7 571.2 74.9 108.4 97.2 97.1 74.9 96.2 223.8 60.0 126.3 99.0 126.7 139.8 52.5 132.1 131.7 376.0 38.0 132.1 130.0 100.4 76.3 97.5 48.3 98.6 98.3 176.7 402.7 104.0 112.8 65.1 102.7 350.6 392.2 234.1 267.3 241.7 259.8 145.9 244.8 414.8 364.5 380.7 303.4 339.9 407.2 208.8 290.8 173.4 155.5 391.5 296.1 408.8 401.5 411.4 183.7 149.7 542.4 252.5 347.8 212.7 306.8 186.4 292.1 269.7 261.2 268.6 245.2 230.0 82.5 338.7 140.2 265.1 292.7 218.9 264.0 229.3 276.5 339.7 281.5 623.8 164.6 103.0 149.2 259.8 346.1 332.2 201.0 179.6 411.5 190.5 118.3 178.1 170.9 323.1 128.0 200.7 327.0 185.7 507.4 107.3 144.4 429.1 246.9 110.5 369.5 142.7 179.9 145.6 134.6 382.1 149.8 149.5 134.0 239.9 132.8 333.9 214.8 205.7 510.2 92.4 92.6 101.3 116.0 95.2 104.5 97.2 97.1 99.0 100.4 98.6 102.7 61.4 48.1 74.5 14.4 65.1 69.8 117.8 274.0 81.4 27.5 145.2 105.2 236.5 131.5 119.0 147.1 10.4 328.4 50.6 84.5 1060.4 124.5 5.0 105.1 76.0 78.3 110.9 132.8 15.4 75.1 212.0 100.8 116.7 77.3 52.6 131.0 73.2 390.0 247.6 40.4 15.4 132.5 221.8 164.2 96.0 10.5 77.3 127.9 133.4 10.3 158.4 76.9 39.1 12.5 18.8 63.8 99.3 101.2 153.7 95.1 176.1 937.8 163.4 24.8 72.3 63.1 105.3 11.2 23.2 146.4 52.6 155.0 56.1 440.0 207.0 119.6 PRDX4 AOE37-2 ENSG00000123131 "Peroxiredoxin 4" Q13162 X 23664262-23686397 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "pancreas: 1212.0" "Cell type enhanced" "Detected in all" "Late spermatids: 1007.4;Plasma cells: 810.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008659, CAB027389, CAB047362, HPA067039" Enhanced Supported "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 4400000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" Cytosol "CAB008659: AB_1620984, CAB027389: , CAB047362: , HPA067039: " "unprognostic (3.82e-2)" "unprognostic (6.05e-2)" "unprognostic (1.09e-1)" "unprognostic (6.06e-3)" "unprognostic (1.64e-1)" "unprognostic (1.65e-2)" "unprognostic (1.29e-3)" "unprognostic (1.08e-1)" "unprognostic (8.32e-2)" "unprognostic (3.75e-2)" "unprognostic (2.97e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (1.33e-6)" "unprognostic (7.44e-2)" "unprognostic (1.29e-1)" "unprognostic (3.56e-1)" "unprognostic (4.10e-2)" 85.7 84.6 25.2 53.9 27.4 34.3 74.9 28.7 36.6 82.3 40.2 72.7 64.0 68.1 19.5 62.5 66.1 64.7 108.6 24.7 28.7 41.8 277.2 47.1 58.7 30.6 26.8 81.2 1212.0 69.2 93.8 96.2 29.6 59.9 78.8 30.2 124.9 63.2 43.7 47.8 51.3 62.9 29.7 71.9 93.5 121.4 27.5 26.5 49.5 25.4 67.1 68.9 55.7 36.8 176.4 238.2 94.5 191.1 523.9 266.6 138.0 229.6 249.2 204.9 297.5 251.4 214.3 150.0 106.1 299.0 233.6 206.5 279.8 142.6 193.8 92.5 551.5 105.8 187.8 322.1 215.9 138.4 96.9 283.6 182.6 197.7 193.5 213.8 262.0 48.4 209.7 535.4 192.8 262.3 70.3 214.5 339.8 329.5 344.9 97.2 244.3 861.2 181.0 60.5 143.8 121.7 212.6 248.6 174.9 504.1 263.1 174.4 172.7 145.1 95.1 378.4 176.1 173.8 228.6 161.5 259.9 177.0 211.9 5.9 65.6 6.9 53.8 107.8 67.4 89.9 68.1 57.1 101.6 56.0 48.4 49.7 4.8 83.8 137.8 71.3 74.6 69.8 25.2 27.4 28.7 36.6 24.7 28.7 30.6 26.8 29.6 29.7 27.5 36.8 143.8 57.7 68.2 5.5 132.8 59.8 88.6 277.2 62.0 16.7 98.8 119.0 50.7 107.2 124.0 49.7 8.4 328.7 17.9 34.0 9.8 270.4 402.0 66.5 117.4 96.2 58.7 60.6 2.4 358.8 531.6 162.1 65.2 117.6 43.1 206.7 92.1 539.5 173.4 11.8 3.3 151.6 187.2 54.2 55.1 1007.4 252.5 47.1 199.3 1.9 75.2 55.0 27.8 8.5 7.3 241.4 44.1 144.0 810.1 174.6 61.2 54.2 89.9 21.7 144.7 79.2 185.3 258.2 251.7 83.3 52.1 258.6 42.0 311.8 115.7 73.1 PRELP "prolargin, SLRR2A" ENSG00000188783 "Proline and arginine rich end leucine rich repeat protein" P51888 1 203475806-203491352 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Fibroblasts: 206.6;Leydig cells: 100.6;Melanocytes: 192.1;Muller glia cells: 152.4;Peritubular cells: 199.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.1" "Group enriched" "Detected in some" 5 "ASC diff: 18.0;BJ: 7.7;fHDF/TERT166: 11.7;SuSa: 5.2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 82.4" HPA059225 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 450000 "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA059225: " "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "prognostic unfavorable (9.70e-5)" "unprognostic (2.83e-2)" "unprognostic (6.56e-2)" "unprognostic (2.75e-2)" "unprognostic (1.61e-1)" "unprognostic (2.84e-2)" "unprognostic (3.98e-2)" "unprognostic (2.04e-1)" "unprognostic (2.80e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (5.62e-6)" "unprognostic (2.81e-2)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.02e-4)" 114.8 23.4 12.6 4.2 14.2 0.5 77.5 7.7 20.2 126.7 20.0 136.4 6.6 147.7 7.6 41.3 108.6 40.4 212.0 11.6 10.0 25.3 15.6 124.7 8.0 10.2 8.2 128.2 13.1 2.5 22.6 12.0 9.4 73.6 8.9 21.5 32.7 77.1 35.6 56.4 61.0 51.4 8.3 44.2 41.3 7.2 10.3 3.2 60.4 36.9 15.9 147.8 92.9 9.4 0.2 0.2 0.5 0.1 18.0 0.5 0.4 7.7 1.0 0.2 0.2 0.0 0.1 1.2 0.6 11.7 0.1 0.6 0.2 0.3 0.3 0.0 0.1 0.2 0.5 0.2 0.0 0.3 0.1 0.0 0.0 0.1 0.2 2.1 0.0 0.4 0.2 0.4 1.3 0.1 0.1 0.5 0.4 0.3 0.1 0.4 0.2 0.4 0.0 0.3 1.0 0.2 0.2 0.2 0.8 5.2 0.2 0.1 0.6 0.5 0.2 0.3 0.1 0.2 0.3 1.2 0.1 0.2 0.5 1.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.1 0.1 0.1 0.0 12.6 14.2 7.7 20.2 11.6 10.0 10.2 8.2 9.4 8.3 10.3 9.4 8.8 0.0 5.8 5.2 0.9 18.2 1.0 0.0 2.2 3.6 4.2 5.1 7.4 1.5 0.6 0.0 2.1 0.1 0.3 0.1 0.0 0.0 1.1 0.6 1.7 15.6 0.0 2.7 1.6 0.0 0.1 206.6 4.6 1.6 5.1 0.2 22.9 0.3 0.3 1.7 0.2 0.0 0.0 0.3 19.2 5.3 100.6 0.9 192.1 22.5 0.0 152.4 0.0 7.5 0.5 0.0 0.0 199.7 0.4 0.6 0.0 0.1 1.5 8.9 26.3 9.6 38.3 3.1 2.4 1.6 9.9 0.3 1.6 0.1 0.0 1.3 PREX2 "DEP.2, DEPDC2, FLJ12987, P-REX2, PPP1R129" ENSG00000046889 "Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2" Q70Z35 8 67952046-68237032 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.1" "Cell type enhanced" "Detected in many" "Astrocytes: 717.6;Microglial cells: 120.9;Oligodendrocyte precursor cells: 422.2;Oligodendrocytes: 222.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.0;HUVEC TERT2: 19.2;JURKAT: 8.3;NTERA-2: 12.1;RH-30: 5.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015234, HPA075956" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "HPA015234: AB_1847604, HPA075956: AB_2686769" "unprognostic (2.25e-1)" "unprognostic (3.32e-2)" "unprognostic (1.30e-2)" "unprognostic (3.39e-2)" "unprognostic (1.79e-1)" "unprognostic (2.37e-2)" "unprognostic (4.19e-1)" "unprognostic (8.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.98e-2)" "unprognostic (2.53e-2)" "unprognostic (8.77e-2)" "prognostic unfavorable (1.61e-7)" "unprognostic (8.30e-3)" "unprognostic (2.79e-1)" "unprognostic (3.67e-2)" "unprognostic (6.64e-2)" 9.3 1.0 11.5 1.2 15.2 0.1 5.5 15.8 9.4 4.4 0.1 2.6 1.7 2.5 1.7 1.7 5.5 3.2 3.8 12.5 10.1 1.6 1.2 4.4 0.8 16.1 13.5 1.9 1.1 1.1 1.9 8.1 13.2 2.5 1.7 3.6 1.3 2.2 2.2 1.7 1.8 2.5 12.6 1.3 1.6 0.9 13.4 0.9 7.3 5.0 1.0 2.7 2.6 14.1 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 8.3 0.0 0.0 0.0 0.0 3.0 0.0 12.1 0.0 0.0 0.0 5.5 0.0 0.7 0.0 3.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.3 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 15.2 15.8 9.4 12.5 10.1 16.1 13.5 13.2 12.6 13.4 14.1 103.3 3.2 5.0 717.6 0.3 4.0 3.6 0.0 0.0 21.8 0.6 0.8 6.1 1.5 3.1 1.8 2.1 0.0 0.6 0.0 0.0 0.2 52.7 15.2 3.2 57.0 0.0 0.0 2.2 0.0 0.0 19.7 0.0 26.2 1.3 0.0 56.4 0.7 0.1 5.0 81.3 0.0 0.0 2.7 5.1 9.6 11.1 0.8 8.8 120.9 0.0 65.8 0.0 422.2 222.1 0.0 0.0 10.5 1.3 0.8 0.0 0.0 0.7 4.1 26.3 3.9 13.8 0.9 1.2 0.5 2.6 0.0 1.1 0.2 0.0 1.6 PRG4 "bG174L6.2, CACP, FLJ32635, HAPO, JCAP, MSF, SZP" ENSG00000116690 "Proteoglycan 4" Q92954 1 186296279-186314567 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 93.2;liver: 185.7" "Group enriched" "Detected in some" 15 "Fibroblasts: 320.6;Hepatocytes: 364.7" "Cancer enriched" "Detected in many" 10 "liver cancer: 28.4" "Region enriched" "Detected in single" 33 "hypothalamus: 30.8" "Immune cell enriched" "Detected in single" 5 "T-reg: 1.2" "Lineage enriched" "Detected in single" 12 "T-cells: 1.2" "Cell line enriched" "Detected in some" 6 "ASC diff: 284.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" CAB054258 Supported "Secreted to extracellular matrix" NA NA 4300000000 "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB054258: " "unprognostic (8.67e-2)" "unprognostic (2.28e-1)" "unprognostic (1.82e-3)" "unprognostic (1.98e-1)" "unprognostic (1.77e-1)" "unprognostic (7.87e-2)" "unprognostic (7.33e-2)" "unprognostic (1.78e-1)" "unprognostic (1.28e-1)" "unprognostic (1.53e-1)" "unprognostic (5.03e-2)" "unprognostic (4.11e-1)" "unprognostic (1.91e-13)" "unprognostic (1.40e-2)" "unprognostic (2.60e-1)" "unprognostic (1.60e-3)" "unprognostic (7.05e-3)" 93.2 2.3 0.0 2.3 0.0 0.3 15.1 0.4 0.9 0.6 3.9 1.2 0.0 0.6 0.9 0.3 20.0 0.4 31.7 0.0 30.8 0.2 185.7 26.4 0.4 0.0 0.0 2.1 1.5 0.0 2.1 0.0 0.1 0.6 0.1 0.1 3.9 0.1 9.5 7.7 0.4 0.3 0.2 0.7 1.4 0.2 0.2 0.3 1.7 8.1 0.3 2.6 0.5 0.0 0.0 0.1 0.0 0.0 284.6 11.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 1.1 0.1 0.2 0.2 0.0 26.2 0.0 44.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.7 1.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 32.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.4 0.9 0.0 30.8 0.0 0.0 0.1 0.2 0.2 0.0 5.1 22.4 16.2 0.0 1.3 0.6 0.0 0.0 0.0 0.0 0.1 0.0 2.7 10.0 21.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.2 3.7 4.1 0.0 2.7 0.0 0.0 0.0 320.6 0.0 0.8 16.4 0.0 6.4 364.7 0.1 0.0 0.1 0.0 0.0 9.4 1.9 0.8 0.0 2.8 1.8 0.0 0.1 0.0 0.0 0.0 0.1 2.6 0.0 0.0 0.1 0.1 0.0 0.0 10.9 0.0 0.0 3.5 1.5 0.0 0.3 0.0 1.1 0.0 2.3 0.1 0.0 0.1 PRICKLE2 DKFZp686D143 ENSG00000163637 "Prickle planar cell polarity protein 2" Q7Z3G6 3 64092236-64445476 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Epilepsy, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 114.3;Excitatory neurons: 185.5;Inhibitory neurons: 232.4;Microglial cells: 112.4;Oligodendrocyte precursor cells: 103.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 24.1;ASC TERT1: 14.9;HSkMC: 22.1;U-87 MG: 15.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035493 Approved "Golgi apparatus,Vesicles" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Vesicles "HPA035493: AB_10696504" "unprognostic (2.87e-1)" "unprognostic (4.31e-1)" "unprognostic (4.45e-2)" "unprognostic (1.25e-1)" "unprognostic (3.40e-1)" "unprognostic (3.53e-3)" "unprognostic (2.92e-2)" "unprognostic (1.56e-2)" "unprognostic (1.92e-1)" "unprognostic (3.83e-2)" "unprognostic (3.03e-2)" "unprognostic (6.35e-2)" "unprognostic (1.32e-3)" "unprognostic (1.10e-2)" "unprognostic (1.91e-1)" "unprognostic (9.04e-3)" "unprognostic (1.77e-1)" 20.8 3.0 14.1 3.9 14.9 0.3 8.0 3.4 15.8 16.4 9.1 18.4 2.3 17.3 6.8 7.7 11.7 8.8 5.6 28.5 10.0 3.8 3.1 10.6 0.8 4.4 8.9 8.4 3.8 5.4 5.6 5.6 6.2 7.3 4.6 10.1 4.9 13.8 1.9 4.3 5.9 16.6 6.3 1.4 8.1 1.7 11.7 1.0 6.9 3.9 1.0 12.4 8.8 9.3 0.0 4.7 1.3 0.1 24.1 14.9 0.0 3.5 4.5 2.8 4.2 8.3 0.1 0.0 0.5 3.4 7.6 0.1 0.0 3.2 2.8 3.3 0.1 0.0 0.5 0.1 6.7 0.0 0.0 22.1 4.0 8.2 3.5 8.4 1.7 0.0 0.0 1.8 3.9 4.6 0.0 0.1 3.0 0.0 0.1 0.0 0.2 0.1 4.5 11.7 1.2 0.2 0.0 0.9 0.1 7.7 1.6 0.1 0.1 11.9 5.4 2.9 6.9 3.7 0.0 0.7 15.5 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 14.1 14.9 3.4 15.8 28.5 10.0 4.4 8.9 6.2 6.3 11.7 9.3 12.4 0.0 10.9 114.3 1.5 6.2 4.1 7.3 7.4 25.6 4.3 8.4 6.2 1.5 7.3 3.7 64.6 1.4 0.3 1.6 0.0 2.7 15.1 24.7 47.5 9.5 0.0 0.0 185.5 0.4 0.4 20.3 0.0 8.7 0.0 5.2 33.5 1.7 4.1 16.8 232.4 0.6 4.1 1.2 1.8 3.5 9.9 0.6 5.4 112.4 0.0 7.5 1.0 103.5 26.4 0.7 0.3 23.0 0.2 0.9 0.0 6.2 7.6 4.4 13.1 14.6 14.3 2.0 1.0 6.2 3.0 4.9 0.6 6.6 1.1 2.7 PRKCB "PKCβ, PKCB, PRKCB1, PRKCB2" ENSG00000166501 "Protein kinase C beta" P05771 16 23835983-24220611 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transporters" "Adaptive immunity, Apoptosis, Immunity, Transcription, Transcription regulation" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.0;lymphoid tissue: 47.2" "Cell type enhanced" "Detected in many" "B-cells: 185.1;Bipolar cells: 208.6;Excitatory neurons: 877.7;Inhibitory neurons: 320.2;Kupffer cells: 221.9" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 95 "amygdala: 28.9;basal ganglia: 53.9;cerebral cortex: 84.0;hippocampal formation: 35.3;white matter: 36.6" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 161.8;HMC-1: 154.8;K-562: 234.9;THP-1: 72.7;U-937: 64.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003843, HPA048321, HPA054203" Approved Supported Nucleoplasm,Cytosol NA NA 380000 "Cluster 6: Non-specific - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Cytosol "CAB003843: AB_562197, HPA048321: AB_2680357, HPA054203: AB_2682416" "unprognostic (1.53e-3)" "unprognostic (4.53e-4)" "unprognostic (2.52e-3)" "unprognostic (3.07e-2)" "unprognostic (1.72e-1)" "unprognostic (7.13e-3)" "unprognostic (2.06e-1)" "unprognostic (1.67e-3)" "unprognostic (3.19e-2)" "unprognostic (1.79e-1)" "unprognostic (7.38e-2)" "unprognostic (1.06e-1)" "unprognostic (3.17e-3)" "unprognostic (2.08e-1)" "unprognostic (2.12e-2)" "unprognostic (3.28e-1)" "unprognostic (4.95e-2)" 4.4 1.6 28.9 30.8 53.9 32.1 1.5 0.5 84.0 4.2 0.0 9.7 5.9 3.8 0.6 3.5 3.8 4.4 1.1 35.3 0.0 2.8 4.2 7.8 47.1 0.0 0.0 0.6 1.0 0.2 1.4 2.7 0.0 7.3 5.1 18.2 1.5 10.2 0.8 5.5 19.4 7.2 0.0 46.2 5.7 8.4 0.0 47.2 4.5 1.0 40.0 8.7 1.7 36.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.5 1.0 0.0 0.3 0.5 0.5 0.0 0.0 0.0 3.2 161.8 7.5 0.0 0.0 23.6 154.8 0.0 0.7 0.0 0.0 0.0 0.0 27.3 234.9 0.6 0.0 0.0 52.1 51.4 1.5 0.0 0.0 49.0 0.4 9.5 0.5 14.1 27.2 0.0 0.2 0.2 2.4 0.8 0.0 72.7 1.1 0.0 0.3 0.1 0.0 4.1 0.0 1.4 0.2 64.4 0.3 39.3 13.3 27.8 24.8 20.0 11.5 44.2 15.9 29.9 11.3 40.0 13.0 32.0 39.1 39.9 28.6 33.8 12.7 15.5 28.9 53.9 0.5 84.0 35.3 0.0 0.0 0.0 0.0 0.0 0.0 36.6 1.1 3.2 4.9 21.5 185.1 6.0 4.1 0.1 0.6 208.6 0.9 0.8 2.0 2.8 1.8 1.8 2.1 0.2 166.3 1.4 0.0 0.0 26.5 0.1 0.1 4.1 0.0 26.3 877.7 0.2 0.3 1.7 1.5 0.1 71.5 1.9 11.4 3.1 50.5 79.1 320.2 1.5 0.0 221.9 20.5 11.7 0.0 100.9 3.6 110.5 154.4 10.8 120.5 102.1 132.5 0.0 9.6 0.4 61.8 1.0 6.7 0.8 1.6 9.9 0.0 4.4 1.6 3.4 3.6 0.5 14.3 0.8 68.1 0.2 3.8 4.5 PRKCQ ENSG00000065675 "Protein kinase C theta" Q04759 10 6427143-6580301 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 33.6;skeletal muscle: 124.5;tongue: 112.6" "Cell type enhanced" "Detected in many" "Astrocytes: 22.9;dendritic cells: 22.4;NK-cells: 32.0;Oligodendrocyte precursor cells: 24.6;Oligodendrocytes: 75.2;T-cells: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "gdT-cell: 23.0;MAIT T-cell: 18.0;memory CD4 T-cell: 24.5;memory CD8 T-cell: 24.5;naive CD4 T-cell: 19.1;naive CD8 T-cell: 17.9;NK-cell: 13.3;T-reg: 39.7" "Group enriched" "Detected in many" 11 "NK-cells: 13.3;T-cells: 39.7" "Cell line enhanced" "Detected in many" "HEL: 57.8;JURKAT: 40.0;MOLT-4: 43.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065279, HPA073098" Enhanced "Centriolar satellite" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Centriolar satellite" "HPA065279: AB_2685453, HPA073098: AB_2686571" "unprognostic (6.61e-3)" "unprognostic (2.12e-1)" "unprognostic (1.87e-1)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (2.69e-3)" "unprognostic (2.46e-1)" "unprognostic (8.40e-2)" "unprognostic (2.66e-1)" "unprognostic (1.17e-1)" "unprognostic (3.22e-1)" "unprognostic (5.26e-2)" "unprognostic (7.74e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (5.27e-4)" "unprognostic (3.51e-2)" 0.8 0.7 5.3 5.2 8.5 5.7 0.9 6.1 6.3 1.6 12.1 1.4 1.5 2.5 8.3 2.2 3.9 1.5 0.3 5.5 8.2 10.9 1.0 5.3 12.3 6.5 8.6 1.3 3.4 0.7 0.8 0.2 6.4 1.8 1.7 1.5 1.4 1.1 124.5 0.3 3.3 0.7 5.5 5.0 2.1 1.1 7.2 33.6 14.9 112.6 9.4 2.2 0.6 9.8 0.1 5.3 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.2 0.4 3.4 0.3 0.0 0.0 0.0 0.0 3.3 6.0 0.0 0.0 3.9 57.8 0.0 0.4 0.7 2.8 0.6 0.3 3.5 0.1 0.2 0.0 0.5 40.0 12.8 0.1 0.0 0.0 43.9 8.0 5.8 0.5 0.0 8.5 1.3 0.0 11.6 2.9 0.4 2.1 0.0 0.0 0.0 3.4 0.0 5.8 0.0 0.0 5.6 0.0 0.0 0.1 0.0 0.0 0.0 7.1 0.0 2.4 0.1 0.3 23.0 0.4 18.0 0.1 24.5 24.5 0.2 0.0 19.1 17.9 1.6 13.3 0.0 0.0 39.7 10.5 5.3 8.5 6.1 6.3 5.5 8.2 6.5 8.6 6.4 5.5 7.2 9.8 0.2 3.2 7.0 22.9 0.8 0.0 0.3 0.3 0.6 1.6 0.3 0.3 0.4 0.0 0.7 1.8 0.0 0.0 22.4 0.0 7.9 0.3 2.1 0.5 1.2 0.2 1.8 8.0 13.7 0.8 0.1 0.7 1.5 3.0 1.3 8.2 1.1 0.0 0.5 0.0 14.7 0.5 0.0 1.3 0.5 5.6 0.0 1.7 0.0 7.5 0.8 1.2 32.0 24.6 75.2 0.1 0.1 0.0 10.2 0.2 0.0 0.3 0.9 0.4 0.0 4.2 0.4 1.0 2.2 0.5 0.0 0.0 31.7 0.3 0.4 0.1 PRKD2 "DKFZP586E0820, HSPC187, PKD2" ENSG00000105287 "Protein kinase D2" Q9BZL6 19 46674275-46717127 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Cell adhesion, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-266/84: 149.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021490, HPA056727" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 57: B-cells - Immune response" Nucleoplasm Cytosol "HPA021490: AB_1855708, HPA056727: AB_2683217" "unprognostic (3.01e-2)" "unprognostic (1.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.06e-2)" "unprognostic (8.91e-2)" "unprognostic (1.99e-2)" "unprognostic (8.79e-3)" "unprognostic (2.61e-1)" "unprognostic (6.22e-2)" "unprognostic (4.21e-3)" "unprognostic (8.89e-2)" "unprognostic (2.74e-1)" "unprognostic (3.45e-3)" "unprognostic (1.04e-2)" "unprognostic (7.19e-2)" "unprognostic (4.34e-2)" "prognostic favorable (9.15e-4)" 29.0 11.5 7.2 23.6 7.3 29.4 29.3 5.4 7.7 26.6 12.5 20.3 17.1 21.8 4.7 27.5 24.1 11.2 13.8 6.1 6.0 19.2 13.8 34.3 31.1 10.0 6.3 21.8 19.1 8.3 24.0 11.1 6.8 23.9 7.1 4.4 24.7 10.0 8.0 46.8 29.9 6.0 6.0 54.3 20.3 6.6 7.7 25.6 28.9 4.8 21.2 19.5 26.9 6.6 19.6 34.5 12.8 16.6 7.3 6.4 15.1 11.5 13.2 19.6 19.7 19.7 21.0 22.3 16.3 13.2 13.2 27.5 9.5 26.0 5.9 19.8 17.5 25.9 11.5 10.2 12.8 21.2 34.7 11.0 15.8 12.7 9.8 12.8 30.1 21.5 14.6 35.4 7.0 23.8 32.7 53.1 9.7 27.4 17.4 25.8 5.8 37.5 11.4 32.7 7.7 22.4 18.8 18.8 4.6 10.6 11.6 7.5 17.6 8.7 18.8 7.1 10.0 31.8 149.1 13.5 8.5 17.7 11.0 0.6 0.7 2.6 3.9 0.7 3.3 4.3 3.9 4.3 0.3 4.1 3.3 3.3 5.3 2.2 0.5 0.0 2.9 1.5 7.2 7.3 5.4 7.7 6.1 6.0 10.0 6.3 6.8 6.0 7.7 6.6 37.8 9.6 9.9 5.9 46.5 22.0 32.0 13.2 22.8 6.4 13.9 11.3 17.2 12.8 13.0 9.2 0.0 13.8 17.5 43.6 7.9 18.6 1.2 15.3 6.7 37.2 21.6 4.0 6.5 28.2 13.8 9.6 23.4 15.0 14.5 14.1 37.1 8.5 9.0 1.7 2.8 21.7 4.1 12.3 11.4 3.1 11.8 8.3 12.4 11.2 9.3 6.5 42.2 4.0 3.1 29.5 35.1 6.8 47.0 22.9 34.1 9.3 15.6 4.4 13.1 6.1 7.6 2.9 17.9 21.2 26.7 29.7 31.9 6.6 15.3 30.2 PROB1 C5orf65 ENSG00000228672 "Proline rich basic protein 1" E7EW31 5 139390592-139395104 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 23.3;skeletal muscle: 81.0" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 7 "HDLM-2: 104.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA053354, HPA060103" Enhanced Enhanced Nucleoplasm NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA053354: , HPA060103: AB_2684205" "unprognostic (4.14e-2)" "prognostic favorable (9.26e-4)" "unprognostic (2.60e-1)" "unprognostic (1.72e-1)" "unprognostic (3.53e-2)" "unprognostic (9.27e-3)" "unprognostic (4.72e-2)" "unprognostic (1.40e-1)" "unprognostic (8.28e-3)" "unprognostic (3.21e-2)" "unprognostic (4.84e-4)" "unprognostic (7.10e-2)" "unprognostic (1.75e-2)" "unprognostic (9.05e-2)" "unprognostic (3.62e-2)" "unprognostic (5.89e-2)" "unprognostic (8.24e-2)" 1.4 4.8 4.2 0.9 3.3 0.4 1.5 3.5 2.5 1.4 2.2 1.9 1.2 1.7 0.4 1.0 2.1 0.4 23.3 3.3 4.5 1.7 0.6 0.9 1.0 6.4 7.8 0.6 0.4 2.3 2.9 0.6 4.9 3.3 0.1 0.3 2.4 1.3 81.0 0.7 1.6 0.5 6.1 1.6 1.2 0.8 5.0 0.7 1.0 18.4 0.6 1.6 1.0 2.9 1.5 0.6 0.3 0.3 0.1 0.3 0.5 1.2 0.3 1.3 1.1 4.3 2.6 5.7 1.1 3.9 0.1 0.7 0.5 0.1 0.3 104.7 1.4 1.4 2.7 0.5 3.0 0.0 3.2 0.9 0.7 2.8 0.6 0.7 0.1 3.7 0.5 5.7 4.1 1.2 4.9 2.6 1.4 0.6 2.7 15.4 0.4 12.5 0.2 0.1 1.3 0.7 6.0 4.5 0.2 1.3 2.1 3.0 0.4 0.1 0.4 0.2 0.4 1.0 1.8 9.2 0.1 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.2 3.3 3.5 2.5 3.3 4.5 6.4 7.8 4.9 6.1 5.0 2.9 2.4 0.0 0.0 0.0 0.7 0.0 0.3 0.0 1.2 0.0 0.4 0.1 29.7 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.1 0.2 2.4 1.5 2.5 0.0 0.4 0.0 0.0 0.3 1.2 1.1 0.9 0.0 0.7 2.9 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.3 0.1 1.2 3.0 0.3 0.0 2.4 0.0 0.2 6.6 5.6 2.9 0.4 0.8 0.3 0.0 2.6 0.4 2.4 0.6 0.3 PROSER3 "C19orf55, FLJ30657" ENSG00000167595 "Proline and serine rich 3" Q2NL68 19 35758143-35771028 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 89.6;Rod photoreceptor cells: 39.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 10.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058492 Approved Approved "Golgi apparatus" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus" "HPA058492: AB_2683733" "unprognostic (1.35e-2)" "unprognostic (1.29e-2)" "unprognostic (6.74e-3)" "unprognostic (3.81e-2)" "unprognostic (1.75e-1)" "unprognostic (9.29e-3)" "unprognostic (1.25e-3)" "unprognostic (5.13e-2)" "unprognostic (2.52e-1)" "unprognostic (1.28e-1)" "unprognostic (2.52e-2)" "unprognostic (8.13e-2)" "prognostic unfavorable (3.74e-7)" "unprognostic (8.60e-2)" "unprognostic (2.41e-1)" "unprognostic (2.87e-2)" "unprognostic (9.54e-2)" 2.3 2.4 3.4 4.3 3.7 5.2 2.3 2.3 5.2 3.4 6.7 2.9 1.8 3.8 2.8 2.5 4.3 3.3 2.5 2.8 0.6 1.9 1.3 2.7 3.0 3.6 2.7 4.1 5.1 3.1 3.8 2.8 1.6 2.4 1.9 3.6 2.6 3.1 1.7 5.8 2.6 3.3 0.0 2.9 4.0 8.8 2.6 4.6 3.8 1.4 2.6 3.1 2.9 2.5 9.3 26.7 9.4 9.3 3.7 3.8 3.1 6.7 7.6 7.3 7.7 8.2 6.3 5.2 7.3 6.4 3.5 5.5 4.0 11.8 4.9 12.5 6.8 7.5 12.2 3.4 3.2 6.0 15.6 4.6 6.5 10.2 9.0 5.7 3.2 6.7 6.6 9.3 6.4 4.6 10.7 2.5 2.6 5.4 3.9 8.2 2.3 3.9 4.7 9.8 9.2 8.1 7.4 5.4 1.0 3.5 8.7 5.1 8.2 7.7 8.1 8.0 7.2 11.9 8.6 4.2 8.0 3.8 6.1 5.7 1.7 4.0 1.1 1.0 1.9 2.4 1.7 1.0 0.4 2.6 1.4 0.5 10.3 0.8 1.0 1.5 1.6 0.2 3.4 3.7 2.3 5.2 2.8 0.6 3.6 2.7 1.6 0.0 2.6 2.5 2.6 9.6 1.5 1.6 7.4 0.0 12.8 0.0 6.2 10.8 3.1 2.9 1.4 8.6 1.8 11.0 89.6 8.2 9.4 5.3 0.0 5.9 30.0 8.9 6.3 3.4 9.5 9.5 3.7 1.9 5.4 5.6 10.2 3.6 2.5 4.4 7.5 2.6 2.8 6.7 2.1 3.9 0.0 2.8 0.0 21.2 14.3 3.3 0.0 1.0 7.0 6.0 13.4 1.0 2.1 5.3 3.4 4.1 3.4 9.2 5.3 1.8 14.6 39.5 6.6 7.9 5.0 27.2 6.5 4.0 0.0 7.3 6.6 15.4 4.7 5.7 PRPSAP1 PAP39 ENSG00000161542 "Phosphoribosyl pyrophosphate synthetase associated protein 1" Q14558 17 76309478-76384521 "Predicted intracellular proteins" "Nucleotide biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062396 Approved Cytosol NA NA 24000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 5: Muller glia cells - Visual perception" Cytosol "HPA062396: AB_2684750" "unprognostic (1.12e-1)" "unprognostic (3.37e-2)" "prognostic favorable (1.39e-5)" "unprognostic (3.31e-2)" "unprognostic (3.11e-2)" "unprognostic (8.45e-3)" "unprognostic (1.09e-1)" "unprognostic (7.19e-2)" "unprognostic (2.66e-2)" "unprognostic (2.37e-2)" "unprognostic (6.51e-2)" "unprognostic (4.10e-3)" "unprognostic (1.29e-1)" "unprognostic (1.22e-1)" "unprognostic (5.72e-2)" "unprognostic (8.20e-2)" "unprognostic (5.37e-2)" 26.4 26.2 24.2 13.7 24.3 22.2 27.6 25.1 29.3 29.1 24.0 22.7 16.6 22.6 28.0 34.9 21.8 18.9 21.5 22.4 26.6 26.4 69.9 27.5 18.5 29.2 26.2 21.1 25.1 43.9 21.9 20.9 29.9 20.7 25.5 29.4 65.8 19.0 16.6 24.7 19.4 23.1 23.5 15.9 23.2 35.6 27.3 18.1 49.3 13.9 26.0 19.0 27.2 26.3 38.6 46.4 54.7 26.9 36.3 32.2 21.5 33.9 46.9 55.7 45.9 33.8 32.4 44.2 18.2 50.9 44.4 22.3 49.8 40.5 55.3 17.4 44.7 32.6 36.0 149.2 45.0 28.0 24.8 35.3 32.4 40.1 34.9 54.1 110.4 44.2 40.1 40.3 37.2 41.2 50.9 25.8 13.8 65.7 41.2 41.0 70.9 32.8 42.7 43.8 31.1 51.0 37.4 37.4 77.8 60.9 61.3 32.5 42.3 63.9 46.8 38.2 42.4 27.0 18.2 31.2 28.4 25.5 27.7 18.3 16.4 22.1 16.4 14.5 17.3 17.2 16.4 15.7 14.2 13.6 13.8 13.4 5.3 19.1 14.1 14.1 24.6 13.4 24.2 24.3 25.1 29.3 22.4 26.6 29.2 26.2 29.9 23.5 27.3 26.3 37.7 0.0 14.2 25.5 18.2 13.0 33.3 42.6 16.5 33.9 34.7 40.6 17.3 38.6 25.0 14.7 35.5 49.4 23.5 21.2 49.0 60.6 32.3 26.2 25.8 43.6 15.7 13.2 29.5 29.6 65.0 21.3 23.9 40.9 20.3 70.3 20.7 38.5 29.9 60.6 52.9 26.0 44.7 18.9 21.3 27.5 29.2 21.9 32.0 15.9 64.2 129.4 18.6 24.6 27.7 38.8 18.7 46.3 16.8 25.1 26.3 27.9 32.5 40.4 59.2 25.7 30.8 118.0 97.7 24.8 14.6 30.6 24.2 19.2 34.3 22.3 PRR29 "C17orf72, DKFZp761M2312, FLJ11724" ENSG00000224383 "Proline rich 29" P0C7W0 17 63998351-64004305 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "fallopian tube: 58.2" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 57.4;Respiratory ciliated cells: 89.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 4.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.5;REH: 3.7;TIME: 2.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA051264 Uncertain Nucleoli NA NA "Cluster 46: Basophils - DNA binding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" Nucleoli "HPA051264: " "unprognostic (2.05e-2)" "unprognostic (6.46e-2)" "unprognostic (2.87e-2)" "unprognostic (2.92e-3)" "unprognostic (4.71e-3)" "unprognostic (3.22e-2)" "unprognostic (3.84e-1)" "unprognostic (3.95e-2)" "unprognostic (1.04e-2)" "unprognostic (1.44e-1)" "unprognostic (2.63e-3)" "unprognostic (5.76e-2)" "unprognostic (1.30e-3)" "unprognostic (6.48e-2)" "unprognostic (1.80e-1)" "unprognostic (1.32e-1)" "unprognostic (9.98e-3)" 2.0 0.3 3.2 0.5 2.5 0.3 2.2 1.8 1.2 6.1 12.7 0.4 0.2 0.6 0.3 0.2 58.2 0.7 1.5 4.1 4.2 1.9 0.2 10.4 0.4 12.7 16.0 0.6 0.3 0.9 10.7 0.3 7.3 0.7 0.0 0.0 0.5 0.6 0.6 0.4 0.7 0.2 9.0 5.7 0.3 13.9 4.0 0.2 4.7 0.0 0.3 0.8 0.6 3.9 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.2 0.0 3.5 0.0 0.3 0.0 0.7 0.0 0.0 0.2 0.1 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 1.0 0.5 0.0 0.0 0.0 1.3 0.0 0.1 0.7 0.1 3.7 0.0 1.5 0.3 0.0 0.2 1.0 0.0 0.1 0.2 0.5 0.5 0.0 2.8 0.1 1.1 0.4 0.1 0.4 0.1 0.2 0.4 0.1 0.0 0.9 0.2 0.0 0.4 0.5 0.1 0.1 0.4 0.2 0.1 0.2 0.7 0.4 0.2 0.2 0.4 0.0 0.2 0.3 3.2 2.5 1.8 1.2 4.1 4.2 12.7 16.0 7.3 9.0 4.0 3.9 3.3 0.0 2.8 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.5 0.6 0.2 1.5 9.9 3.7 0.0 0.0 0.7 0.0 0.0 0.1 12.4 57.4 0.5 2.1 0.0 0.0 0.5 0.0 0.1 0.6 0.0 1.1 0.0 1.6 1.8 0.5 0.3 0.0 0.4 0.0 0.0 0.0 0.0 10.5 0.0 0.9 0.0 1.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.7 2.0 0.0 0.0 0.1 89.6 0.0 0.0 0.3 0.3 18.1 1.4 0.0 0.0 0.3 0.7 3.5 0.0 0.1 PRSS22 "BSSP-4, hBSSP-4, SP001LA" ENSG00000005001 "Serine protease 22" Q9GZN4 16 2852730-2858170 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 79.6;salivary gland: 26.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 221.0;Club cells: 343.9;Ionocytes: 207.5;Pancreatic endocrine cells: 380.6;Urothelial cells: 479.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CAPAN-2: 17.3;MCF7: 14.6;RT4: 10.4;SK-BR-3: 22.9" "Region enhanced" "Detected in some" "cerebral cortex: 2.6" "Low region specificity" "Detected in all" HPA049161 Approved Approved Nucleoplasm "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA049161: AB_2680660" "unprognostic (1.45e-1)" "unprognostic (9.80e-2)" "unprognostic (3.50e-2)" "unprognostic (4.48e-1)" "unprognostic (2.29e-4)" "unprognostic (2.58e-1)" "unprognostic (4.42e-2)" "unprognostic (1.52e-2)" "unprognostic (5.06e-1)" "unprognostic (7.52e-2)" "unprognostic (3.74e-3)" "unprognostic (4.12e-1)" "unprognostic (2.32e-4)" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (2.75e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 23.4 0.0 0.5 0.3 0.7 0.4 79.6 1.3 0.8 0.0 0.0 0.0 16.7 0.5 2.9 0.0 0.0 0.0 0.0 5.8 1.5 2.4 1.1 0.0 6.0 0.5 0.0 26.9 0.3 0.0 3.2 0.2 0.0 0.0 0.0 5.4 0.0 0.0 0.0 1.3 0.0 2.2 2.5 23.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.3 17.3 0.0 0.0 0.0 0.0 1.8 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 22.9 0.0 0.0 2.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.2 4.2 0.0 0.2 23.2 221.0 128.8 28.5 0.0 42.8 23.7 0.3 38.6 343.9 16.5 0.0 36.7 1.9 18.5 1.9 113.1 0.0 28.4 4.6 1.8 3.6 0.0 0.0 98.3 37.1 1.3 52.5 56.6 0.0 0.0 0.0 0.1 2.3 0.0 0.0 7.5 207.5 0.0 1.4 0.0 0.0 0.9 7.2 0.0 1.0 0.0 0.0 0.0 0.0 380.6 32.3 0.0 0.3 75.4 0.6 0.2 108.0 0.0 0.0 0.0 13.7 0.1 0.2 22.7 27.6 10.5 2.7 0.0 6.9 479.5 PRSS23 "SIG13, SPUVE" ENSG00000150687 "Serine protease 23" O95084 11 86791059-86952910 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 249.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 367.1;Endothelial cells: 502.1;Granulosa cells: 347.3;Hepatic stellate cells: 591.8;Theca cells: 445.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 104.6" "Group enriched" "Detected in many" 25 "NK-cells: 34.2;T-cells: 104.6" "Cell line enhanced" "Detected in many" "GAMG: 1093.7;hTERT-RPE1: 1296.9;TIME: 1138.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030591 Uncertain "Secreted to blood" NA NA 440000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA030591: AB_10602067" "unprognostic (2.68e-2)" "unprognostic (1.20e-2)" "unprognostic (1.90e-1)" "unprognostic (2.04e-1)" "unprognostic (2.40e-3)" "prognostic unfavorable (2.12e-4)" "unprognostic (1.89e-2)" "unprognostic (4.30e-2)" "unprognostic (2.08e-1)" "unprognostic (2.09e-1)" "prognostic unfavorable (5.56e-4)" "unprognostic (5.35e-2)" "prognostic unfavorable (3.06e-4)" "unprognostic (5.13e-3)" "unprognostic (9.44e-2)" "unprognostic (1.99e-3)" "unprognostic (8.01e-2)" 55.0 21.4 7.8 35.3 7.8 2.1 43.2 7.1 8.7 249.1 12.9 103.6 19.2 103.4 13.4 22.1 24.9 83.8 28.3 7.9 8.0 42.4 15.0 63.3 21.8 14.0 13.9 26.8 29.8 36.0 16.4 61.7 8.8 61.3 50.3 2.7 52.4 128.2 79.6 19.4 29.0 115.5 7.1 18.0 54.2 31.8 14.1 17.5 40.9 18.7 10.2 99.6 79.1 7.4 62.7 153.3 161.1 1.0 70.4 172.3 0.7 269.0 244.4 293.2 232.6 368.1 484.7 0.2 208.2 414.7 1093.7 126.2 2.6 205.0 70.9 0.7 13.0 21.1 74.7 1.4 36.3 0.1 0.9 137.4 26.8 143.2 162.1 1296.9 604.8 0.9 1.3 0.3 223.4 87.7 0.2 0.3 9.8 211.7 16.8 0.0 0.0 0.7 111.5 82.3 1.5 1.0 59.9 4.5 18.7 397.6 6.0 0.6 1138.2 174.0 2.3 351.7 154.5 1.3 1.3 0.8 124.2 0.5 176.3 0.2 0.2 0.1 104.6 0.1 0.2 0.2 17.8 60.0 0.2 0.0 4.7 50.4 1.6 34.2 2.7 0.2 0.0 39.9 7.8 7.8 7.1 8.7 7.9 8.0 14.0 13.9 8.8 7.1 14.1 7.4 95.8 28.9 14.5 14.0 3.2 15.4 96.2 367.1 2.8 1.6 44.7 78.0 4.3 37.1 231.3 53.3 2.1 18.4 53.4 154.8 7.9 162.6 3.1 10.3 130.3 502.1 13.8 20.4 26.3 83.5 15.7 117.1 22.4 7.0 2.5 347.3 591.8 5.2 5.0 0.0 16.5 30.6 85.5 36.6 18.2 6.6 14.3 5.4 72.9 39.4 1.5 0.8 180.2 11.6 2.3 257.7 80.1 7.5 5.8 100.1 5.2 5.7 90.1 0.9 39.5 14.4 105.9 3.0 7.3 1.7 9.8 4.5 24.0 445.1 11.1 60.2 PRSS35 "C6orf158, dJ223E3.1, MGC46520" ENSG00000146250 "Serine protease 35" Q8N3Z0 6 83512534-83525704 "Enzymes, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 50.5" "Cell type enriched" "Detected in some" 36 "Muller glia cells: 410.9" "Group enriched" "Detected in some" 4 "glioma: 2.8;testis cancer: 4.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "MAIT T-cell: 19.5" "Lineage enriched" "Detected in single" 195 "T-cells: 19.5" "Cell line enhanced" "Detected in some" "BJ hTERT+: 10.4;CACO-2: 86.3;HAP1: 12.8;RPTEC TERT1: 24.6;SuSa: 17.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 2.9;cerebellum: 3.6;cerebral cortex: 5.8;hippocampal formation: 5.3;olfactory bulb: 2.7" "HPA038787, HPA038788" Uncertain "Secreted in female reproductive system" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 5: Muller glia cells - Visual perception" "HPA038787: AB_10675951, HPA038788: AB_2676208" "unprognostic (6.17e-2)" "unprognostic (8.75e-2)" "unprognostic (1.19e-2)" "unprognostic (2.63e-2)" "unprognostic (1.16e-1)" "unprognostic (4.03e-2)" "unprognostic (3.70e-4)" "unprognostic (6.08e-2)" "unprognostic (1.18e-3)" "unprognostic (2.33e-2)" "unprognostic (7.01e-2)" "unprognostic (9.07e-2)" "unprognostic (3.88e-6)" "unprognostic (7.15e-3)" "unprognostic (5.81e-2)" "unprognostic (2.82e-2)" "unprognostic (3.54e-4)" 1.3 2.4 2.9 0.1 3.8 0.0 0.3 1.7 6.8 2.9 1.5 0.1 0.3 1.3 1.1 0.3 1.4 4.2 4.4 3.2 2.1 3.1 0.4 1.3 0.7 1.8 1.9 10.2 0.3 0.3 1.1 3.6 1.8 1.1 0.3 50.5 0.3 0.4 0.1 0.2 0.1 1.5 1.8 0.7 0.3 3.1 2.6 0.1 0.4 0.1 0.1 1.3 0.5 2.2 0.0 0.5 1.9 0.0 0.1 0.0 0.0 0.3 10.4 1.0 2.0 86.3 0.0 0.0 0.1 0.4 0.0 0.0 12.8 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 3.1 0.0 1.2 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.1 1.6 0.4 8.2 0.0 0.0 0.0 24.6 0.0 0.0 1.0 0.0 0.0 0.0 17.9 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 19.5 0.0 0.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 3.8 1.7 6.8 3.2 2.1 1.8 1.9 1.8 1.8 2.6 2.2 0.3 3.2 0.5 8.1 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.1 1.5 0.0 0.0 1.8 0.0 0.3 0.0 0.1 9.8 0.1 0.1 0.0 0.3 0.8 1.8 0.0 0.2 0.0 0.0 4.4 0.0 0.0 0.0 0.9 0.0 0.3 0.4 6.7 0.2 0.0 0.0 0.0 0.0 0.2 1.2 0.1 0.0 1.0 0.0 410.9 0.0 1.0 0.1 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 11.4 6.6 0.1 3.7 0.1 0.5 0.0 0.0 0.1 0.7 5.1 0.0 0.0 PSTPIP1 "CD2BP1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PSTPIP" ENSG00000140368 "Proline-serine-threonine phosphatase interacting protein 1" O43586 15 76993359-77037475 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion, Endocytosis, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 56.6;lymphoid tissue: 33.9" "Cell type enhanced" "Detected in many" "dendritic cells: 60.0;Enteroendocrine cells: 60.0;Hofbauer cells: 42.5;Kupffer cells: 41.8;Macrophages: 41.8;monocytes: 51.1;NK-cells: 91.6;T-cells: 68.4;Theca cells: 78.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 55.1;HL-60: 14.4;NB-4: 20.9;THP-1: 14.7;U-937: 59.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA010116, HPA010600, HPA072744" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA010116: , HPA010600: AB_1855870, HPA072744: " "unprognostic (4.42e-3)" "unprognostic (1.31e-3)" "unprognostic (3.56e-2)" "prognostic favorable (4.74e-5)" "unprognostic (3.79e-2)" "unprognostic (1.12e-3)" "unprognostic (2.16e-2)" "unprognostic (1.23e-2)" "unprognostic (1.16e-1)" "unprognostic (9.85e-2)" "unprognostic (2.96e-2)" "unprognostic (3.18e-1)" "prognostic unfavorable (7.36e-9)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (1.91e-1)" "unprognostic (5.42e-2)" 6.0 2.6 2.8 11.7 2.7 56.6 2.3 2.7 3.1 2.0 3.4 3.3 2.5 1.6 0.1 2.0 3.1 2.9 2.4 2.7 2.8 3.4 3.4 10.4 13.5 3.1 3.1 1.0 1.3 0.2 1.6 1.8 3.0 2.9 0.8 0.1 2.4 1.0 1.5 1.8 9.4 1.4 3.1 33.9 2.9 0.7 3.6 4.2 2.9 1.0 5.5 4.3 2.7 3.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.1 0.0 55.1 0.0 0.0 0.0 3.3 0.0 14.4 0.1 0.2 0.1 0.0 0.1 0.0 0.0 3.0 0.0 0.0 0.0 0.0 2.4 20.9 0.1 0.0 0.0 0.8 0.0 0.1 0.0 0.1 4.0 0.6 0.0 0.1 0.0 0.0 0.0 14.7 0.0 0.0 0.1 0.1 0.0 0.0 1.3 2.4 0.1 59.8 0.0 4.8 71.5 71.4 39.9 33.5 30.8 13.3 27.2 32.7 59.0 18.5 14.3 22.3 85.3 41.6 38.3 5.2 27.0 42.2 2.8 2.7 2.7 3.1 2.7 2.8 3.1 3.1 3.0 3.1 3.6 3.1 1.1 0.0 5.1 1.0 19.2 9.3 1.2 0.4 0.0 1.1 0.9 1.1 1.9 0.0 2.5 0.0 0.0 0.3 60.0 3.1 0.0 0.0 9.6 0.3 0.3 0.8 60.0 4.8 0.4 0.2 0.7 1.9 0.0 0.3 2.5 0.1 2.2 0.9 42.5 0.0 0.1 6.1 2.0 41.8 36.5 18.6 0.9 41.8 7.2 0.0 51.1 0.2 91.6 5.5 1.0 0.1 2.5 2.6 8.5 0.3 0.3 0.4 0.0 0.4 0.0 0.8 3.1 0.2 1.2 0.2 4.8 0.5 68.4 78.1 0.3 1.2 PTAFR ENSG00000169403 "Platelet activating factor receptor" P25105 1 28147166-28193936 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.1;lymphoid tissue: 30.8" "Cell type enhanced" "Detected in many" "granulocytes: 75.4;Hofbauer cells: 71.7;Kupffer cells: 93.0;Langerhans cells: 67.8;Macrophages: 64.5;monocytes: 52.8;Pancreatic endocrine cells: 89.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 256.7;eosinophil: 906.5;neutrophil: 747.1" "Group enriched" "Detected in many" 5 "granulocytes: 906.5;monocytes: 256.7" "Group enriched" "Detected in some" 4 "HBEC3-KT: 36.6;HMC-1: 131.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027543 Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" "Plasma membrane" "HPA027543: AB_10610287" "unprognostic (2.22e-2)" "unprognostic (2.59e-2)" "unprognostic (6.73e-2)" "unprognostic (1.24e-1)" "unprognostic (2.75e-1)" "unprognostic (3.74e-2)" "unprognostic (1.07e-1)" "unprognostic (1.72e-1)" "unprognostic (3.35e-1)" "unprognostic (1.23e-1)" "unprognostic (2.39e-1)" "unprognostic (1.60e-1)" "unprognostic (2.79e-2)" "unprognostic (3.52e-1)" "unprognostic (2.59e-2)" "unprognostic (5.48e-2)" "unprognostic (1.38e-2)" 10.4 2.4 4.3 30.8 4.7 41.1 3.4 4.7 5.6 3.4 4.1 5.5 4.1 1.7 1.2 7.2 2.6 7.2 2.0 3.8 5.1 2.7 4.1 17.8 13.5 8.9 6.6 1.3 2.0 1.6 0.6 7.3 7.7 1.5 6.7 0.5 2.3 1.5 0.7 5.4 6.3 7.9 8.1 14.4 3.8 1.3 7.2 3.6 1.9 2.6 18.0 14.4 1.9 11.8 20.1 0.2 0.1 0.4 0.2 0.0 0.5 0.0 0.0 0.7 0.2 0.2 5.7 1.3 0.1 0.1 0.3 13.5 0.5 36.6 0.8 0.4 0.6 7.7 0.2 0.9 0.1 1.9 131.3 0.0 6.0 0.4 0.4 0.0 0.2 0.1 0.5 0.4 0.0 1.3 0.2 19.3 0.6 0.5 0.2 0.3 0.1 0.1 8.7 2.1 0.3 0.1 0.1 18.1 0.2 0.4 0.4 5.4 0.1 0.2 0.7 0.0 0.2 1.2 1.1 5.6 0.1 2.4 0.6 61.7 256.7 906.5 0.6 77.9 1.2 12.5 0.4 0.4 116.1 6.7 0.5 0.7 747.1 0.7 34.1 1.3 1.2 112.4 4.3 4.7 4.7 5.6 3.8 5.1 8.9 6.6 7.7 8.1 7.2 11.8 2.1 6.4 6.7 0.0 4.1 6.5 2.0 37.9 5.2 1.5 0.8 0.5 2.2 1.5 20.9 1.8 2.1 0.6 2.9 0.4 0.0 18.1 0.4 0.5 0.2 7.3 0.0 4.0 0.9 5.1 0.5 1.3 1.1 0.5 75.4 2.0 2.9 1.0 71.7 0.0 0.7 0.0 18.3 93.0 67.8 0.2 0.6 64.5 0.0 15.0 52.8 0.2 0.0 1.5 6.6 89.8 0.6 0.0 0.5 0.6 0.3 0.2 20.2 0.9 0.0 0.6 1.0 2.3 0.7 3.2 2.8 1.5 2.0 0.0 0.4 9.4 PTDSS1 "KIAA0024, PSS1, PSSA" ENSG00000156471 "Phosphatidylserine synthase 1" P48651 8 96261902-96336995 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 10.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016852 Uncertain Approved "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" "Endoplasmic reticulum" Nucleoplasm "HPA016852: AB_1855878" "unprognostic (1.44e-1)" "unprognostic (1.71e-1)" "unprognostic (1.08e-1)" "unprognostic (7.89e-3)" "unprognostic (7.48e-2)" "unprognostic (5.68e-3)" "prognostic unfavorable (1.08e-5)" "prognostic unfavorable (9.83e-4)" "unprognostic (2.79e-1)" "unprognostic (1.71e-2)" "unprognostic (2.36e-2)" "unprognostic (1.19e-1)" "unprognostic (2.29e-3)" "unprognostic (4.78e-2)" "unprognostic (1.79e-1)" "unprognostic (4.08e-2)" "unprognostic (3.55e-2)" 1.6 2.2 1.6 3.4 2.0 4.9 3.1 1.2 2.6 3.5 0.8 3.4 4.1 2.1 2.8 3.7 2.5 3.1 7.2 1.8 1.0 3.7 4.6 2.6 5.6 0.5 0.6 3.6 2.7 8.0 0.6 4.6 1.3 1.9 2.9 0.9 2.0 3.5 2.9 3.2 3.2 3.6 0.2 2.6 1.4 1.9 2.0 3.6 4.5 3.0 5.2 2.6 1.1 1.4 14.9 11.6 2.0 5.5 4.2 8.5 3.4 10.6 15.5 10.6 7.5 4.6 4.2 24.9 9.5 10.5 2.1 6.0 14.1 11.1 16.1 12.5 10.3 24.5 19.8 2.5 4.3 17.8 8.1 7.2 10.9 14.4 10.2 2.7 7.0 7.6 12.5 12.3 9.7 4.4 14.0 3.0 3.1 5.1 11.1 10.9 10.1 18.8 5.7 12.5 8.6 3.5 3.9 3.4 1.4 2.3 8.2 6.3 11.8 9.1 5.5 6.3 12.3 2.5 13.3 11.8 5.7 19.3 7.5 10.5 2.6 1.5 1.7 1.6 2.5 1.7 2.8 2.2 4.0 2.2 2.5 1.8 0.9 3.2 1.7 1.2 1.7 6.7 1.6 2.0 1.2 2.6 1.8 1.0 0.5 0.6 1.3 0.2 2.0 1.4 12.4 19.2 9.1 8.8 50.5 31.6 18.9 22.6 42.7 10.2 22.9 18.4 94.5 14.3 15.6 11.0 10.4 78.4 23.6 11.9 1.9 20.5 60.1 6.6 9.1 22.9 5.4 38.3 29.3 44.9 54.1 18.0 14.8 9.3 32.4 17.6 34.2 32.1 45.9 5.0 29.2 17.1 10.2 45.3 31.5 52.2 23.3 36.0 19.6 15.9 39.3 4.7 29.9 21.1 8.7 23.9 11.9 25.9 45.5 21.4 16.6 19.0 5.2 4.7 0.0 13.8 15.8 12.1 18.8 33.1 33.5 80.9 34.3 14.6 34.8 16.3 PTDSS2 PSS2 ENSG00000174915 "Phosphatidylserine synthase 2" Q9BVG9 11 448268-491399 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Early spermatids: 144.6;Late spermatids: 347.6;Spermatocytes: 98.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HEK 293: 67.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038928, HPA038929" Approved NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "HPA038928: AB_10672832, HPA038929: AB_2676274" "unprognostic (3.41e-1)" "unprognostic (2.52e-1)" "unprognostic (2.07e-1)" "unprognostic (5.75e-3)" "unprognostic (3.19e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (5.12e-9)" "unprognostic (6.18e-2)" "unprognostic (1.09e-1)" "unprognostic (1.89e-2)" "unprognostic (1.41e-3)" "unprognostic (6.41e-2)" "unprognostic (1.11e-2)" "unprognostic (3.39e-2)" "unprognostic (2.48e-1)" "unprognostic (2.25e-1)" "unprognostic (1.09e-1)" 13.8 21.3 6.2 2.2 9.6 2.2 12.5 8.6 8.6 16.3 8.4 15.4 1.5 15.4 3.7 12.0 14.7 3.9 25.2 6.3 6.1 21.0 13.5 12.8 2.3 10.6 9.1 21.9 18.9 13.6 13.7 5.8 8.1 17.0 2.2 3.1 11.4 5.2 17.7 11.9 10.4 4.9 6.7 12.6 15.5 47.2 8.4 3.3 17.4 5.5 2.0 14.2 12.0 12.6 15.7 15.6 12.8 18.5 11.0 18.2 15.9 13.1 15.5 16.7 14.7 4.1 10.5 8.3 11.0 17.0 15.1 25.4 15.7 20.8 8.0 13.9 67.2 10.5 11.9 9.6 21.3 13.9 8.8 20.8 15.2 5.8 10.1 14.6 13.2 9.8 30.9 2.5 13.3 2.2 13.9 13.3 18.1 12.4 36.8 14.7 14.4 4.1 11.9 3.1 19.3 10.6 18.4 11.9 15.2 13.9 4.3 8.1 16.1 7.7 5.1 3.9 8.5 10.3 4.8 3.6 13.5 6.4 5.6 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.1 0.0 0.2 0.0 0.0 6.2 9.6 8.6 8.6 6.3 6.1 10.6 9.1 8.1 6.7 8.4 12.6 10.3 0.0 6.1 18.6 6.2 4.8 8.3 6.1 6.2 36.9 11.1 11.0 20.1 5.7 6.7 7.3 29.2 19.6 3.0 12.5 5.9 13.3 144.6 7.1 11.1 11.4 16.1 8.2 21.1 13.1 21.3 12.9 9.7 7.5 0.0 30.1 9.3 6.0 17.2 21.9 17.8 7.6 8.2 4.7 4.2 347.6 17.1 6.9 5.4 5.6 5.8 22.7 2.1 18.6 26.8 11.7 6.9 15.4 9.5 10.5 7.0 17.7 4.9 29.8 6.6 11.3 12.9 98.2 24.7 8.2 5.1 17.4 4.9 34.1 9.0 6.1 PTGDR "DP, DP1, PTGDR1" ENSG00000168229 "Prostaglandin D2 receptor" Q13258 14 52267698-52276724 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "Mast cell degranulation" "G-protein coupled receptor, Receptor, Transducer" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 7.9;lymphoid tissue: 6.3" "Cell type enhanced" "Detected in some" "dendritic cells: 50.6;NK-cells: 187.4;T-cells: 31.4" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.0" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "gdT-cell: 68.0;NK-cell: 90.3" "Group enriched" "Detected in many" 33 "NK-cells: 90.3;T-cells: 68.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA049668 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA049668: " "unprognostic (9.32e-3)" "unprognostic (3.31e-2)" "unprognostic (1.00e-2)" "unprognostic (2.04e-3)" "unprognostic (4.80e-2)" "unprognostic (2.70e-2)" "unprognostic (3.11e-3)" "unprognostic (5.00e-2)" "unprognostic (9.38e-3)" "unprognostic (4.94e-2)" "unprognostic (1.81e-2)" "unprognostic (1.54e-1)" "unprognostic (5.60e-8)" "unprognostic (1.14e-2)" "unprognostic (2.32e-1)" "unprognostic (4.02e-2)" "unprognostic (5.89e-2)" 2.0 0.5 0.2 2.1 1.7 1.4 1.2 0.8 0.7 2.1 2.6 5.6 0.7 1.5 1.0 0.4 1.3 1.6 1.9 0.1 0.3 0.5 1.1 1.7 3.2 2.4 0.6 0.8 0.3 0.4 2.1 0.2 0.4 0.8 7.9 0.0 1.1 0.4 0.6 0.6 1.4 0.8 1.5 6.3 1.3 0.2 0.4 0.9 1.1 0.4 1.1 0.9 1.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 68.0 0.0 33.5 0.1 9.0 40.9 0.1 0.0 1.4 22.5 2.3 90.3 0.4 0.2 0.2 12.9 0.2 1.7 0.8 0.7 0.1 0.3 2.4 0.6 0.4 1.5 0.4 0.1 2.9 3.2 0.0 0.0 0.9 0.5 0.0 0.0 0.6 0.0 0.3 0.3 0.4 0.0 0.0 0.0 0.0 0.0 50.6 3.2 0.0 0.0 0.0 0.2 0.1 2.0 1.2 2.7 0.2 0.0 0.0 1.5 1.1 0.1 1.3 0.2 2.2 0.5 0.1 0.0 0.2 7.5 0.0 1.9 0.4 0.0 0.0 4.6 1.8 1.0 0.4 0.0 187.4 0.0 0.1 0.0 2.8 0.0 4.0 0.0 0.2 0.1 0.0 0.0 0.0 0.8 5.5 0.0 0.0 0.1 0.1 0.0 31.4 2.2 14.6 0.0 PTGDS "L-PGDS, PGDS" ENSG00000107317 "Prostaglandin D2 synthase" P41222 9 136975092-136981742 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Mast cell degranulation, Prostaglandin biosynthesis, Prostaglandin metabolism, Transport" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 4898.3;testis: 3242.2" "Group enriched" "Detected in many" 11 "Leydig cells: 38051.3;Peritubular cells: 65156.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 27 "plasmacytoid DC: 1386.8" "Lineage enriched" "Detected in many" 27 "dendritic cells: 1386.8" "Group enriched" "Detected in some" 6 "HHSteC: 518.7;HSkMC: 252.0" "HPA004938, CAB009916, HPA067456" Uncertain "Secreted to blood" NA NA 2500000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "CAB009916: AB_2174617, HPA004938: AB_1855745, HPA067456: " "unprognostic (2.79e-2)" "unprognostic (3.96e-3)" "unprognostic (9.70e-2)" "unprognostic (5.71e-3)" "unprognostic (6.50e-2)" "unprognostic (1.43e-3)" "unprognostic (2.85e-1)" "unprognostic (2.01e-2)" "unprognostic (6.50e-2)" "unprognostic (1.31e-2)" "unprognostic (1.95e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (1.19e-7)" "unprognostic (8.49e-3)" "unprognostic (1.18e-1)" "unprognostic (2.44e-1)" "unprognostic (3.21e-2)" 391.1 297.1 1849.2 247.1 2423.8 9.9 121.1 2440.1 2559.6 1675.5 1508.4 84.8 31.5 320.4 735.9 172.5 492.1 396.7 4898.3 1760.9 2034.8 466.5 80.2 607.8 824.1 2339.4 2228.2 66.8 113.2 9.1 398.4 227.8 2318.0 727.0 17.7 146.1 97.8 813.1 108.3 164.9 205.9 99.7 1999.6 317.5 93.0 3242.2 2264.9 127.4 55.1 60.0 306.0 230.3 1181.0 2580.3 0.1 0.0 0.1 0.0 5.4 16.7 8.8 0.3 0.0 0.0 0.0 0.0 0.2 0.6 4.0 24.0 0.0 0.8 0.6 0.2 0.0 0.0 0.0 0.0 1.4 0.3 518.7 0.3 1.3 252.0 0.1 0.0 0.0 1.8 0.0 0.0 0.6 1.0 0.2 0.0 0.0 6.6 0.9 8.2 0.0 0.1 0.2 1.6 0.0 0.0 1.6 2.0 0.0 0.6 0.0 0.1 0.6 68.3 0.7 0.2 0.2 2.1 0.1 0.3 0.0 0.1 3.9 0.0 0.9 0.0 0.3 0.4 50.5 1.0 3.4 0.3 4.3 6.3 1.8 0.2 0.9 9.9 2.3 3.8 0.2 1386.8 1.4 11.2 1849.2 2423.8 2440.1 2559.6 1760.9 2034.8 2339.4 2228.2 2318.0 1999.6 2264.9 2580.3 29.3 0.0 0.6 665.0 1.5 70.4 3.2 0.1 5.7 46.8 6.6 14.7 333.6 8.6 0.1 138.0 52.1 14.4 1863.6 0.2 68.4 0.3 215.9 29.7 1156.5 167.8 0.0 13.5 4.0 0.0 55.0 1584.0 1.1 20.1 1.3 0.3 46.1 1.6 57.3 21.9 12.8 0.0 0.0 3.4 161.8 1230.9 38051.3 57.0 209.9 176.1 4.6 4625.8 583.9 63.3 850.4 1.7 0.0 65156.8 6.0 20.7 0.0 1.1 0.0 130.3 164.3 787.4 124.8 130.7 111.1 12.0 80.1 35.4 61.3 0.1 0.0 14.5 PTPN13 "PTP-BAS, PTP-BL, PTP1E, PTPL1" ENSG00000163629 "Protein tyrosine phosphatase non-receptor type 13" Q12923 4 86594315-86815171 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 124.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 223.1;Astrocytes: 165.2;Oligodendrocytes: 200.2;Rod photoreceptor cells: 179.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 117.6;RT4: 57.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002213, HPA063119" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "CAB002213: AB_564089, HPA063119: " "unprognostic (5.36e-2)" "unprognostic (4.46e-1)" "unprognostic (1.11e-1)" "unprognostic (2.54e-3)" "unprognostic (4.02e-1)" "unprognostic (9.03e-3)" "unprognostic (4.43e-2)" "unprognostic (4.38e-2)" "unprognostic (2.46e-1)" "unprognostic (7.05e-2)" "unprognostic (3.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.28e-3)" "unprognostic (3.95e-3)" "unprognostic (2.26e-1)" "unprognostic (2.66e-1)" "unprognostic (2.85e-2)" 14.0 6.7 9.9 3.0 16.6 0.3 11.7 8.1 10.8 18.8 22.4 5.2 0.8 13.1 25.5 22.2 13.0 7.7 6.1 14.2 10.6 26.6 1.4 22.9 5.2 16.7 13.1 28.7 4.9 17.5 16.8 3.3 10.5 11.0 2.4 124.3 6.6 10.6 1.0 55.9 2.6 7.9 8.2 4.0 4.1 15.8 13.8 7.6 20.8 5.0 11.5 20.7 22.7 20.4 13.8 6.8 117.6 11.5 48.2 41.9 0.0 25.0 51.0 9.4 11.7 0.1 6.8 0.0 5.3 28.0 3.3 44.4 20.6 37.9 18.0 0.3 15.1 11.4 14.6 0.0 5.9 20.5 0.1 27.2 11.8 6.8 22.4 19.7 0.0 0.0 0.0 19.2 0.0 6.2 1.8 7.4 26.5 0.0 5.1 4.1 0.0 0.0 35.6 57.2 6.8 9.8 7.4 16.4 13.3 18.8 9.6 0.7 0.0 9.1 6.9 0.2 3.3 19.8 0.0 0.0 9.5 0.0 4.0 0.0 0.1 0.0 0.1 1.3 0.9 0.0 0.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 9.9 16.6 8.1 10.8 14.2 10.6 16.7 13.1 10.5 8.2 13.8 20.4 5.3 48.1 223.1 165.2 0.6 109.4 25.6 26.3 79.1 11.6 11.2 8.9 1.8 11.5 52.0 47.8 91.8 0.2 0.3 0.1 3.9 5.0 23.2 16.9 49.4 3.7 4.8 0.8 67.0 3.7 0.1 28.8 4.1 7.7 5.1 7.5 3.6 0.1 0.3 1.7 39.3 1.1 8.2 1.4 10.6 20.8 45.7 4.5 19.6 51.5 0.5 20.3 0.0 75.4 200.2 6.2 2.7 32.7 3.0 16.0 0.1 10.9 27.3 179.0 13.1 10.1 20.8 25.4 20.5 97.8 99.4 0.3 6.6 14.0 0.7 52.5 PTPN22 "Lyp, Lyp1, Lyp2, PTPN8" ENSG00000134242 "Protein tyrosine phosphatase non-receptor type 22" Q9Y2R2 1 113813811-113871753 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Immunity" "Hydrolase, Protein phosphatase" "Diabetes mellitus, Disease variant, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.0;lymphoid tissue: 20.3" "Group enriched" "Detected in many" 4 "B-cells: 67.4;dendritic cells: 176.0;NK-cells: 108.1;Plasma cells: 79.6;T-cells: 151.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 69.3;HL-60: 27.7;U-266/70: 29.2;U-698: 37.5;U-937: 28.4" "Region enriched" "Detected in single" 11 "cerebellum: 5.3" "Not detected" "Not detected" "HPA004912, CAB012209, HPA013350" Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Vesicles, Plasma membrane" "CAB012209: , HPA004912: AB_10602069, HPA013350: AB_10601570" "unprognostic (2.25e-2)" "unprognostic (5.31e-3)" "unprognostic (3.48e-1)" "unprognostic (3.33e-4)" "unprognostic (9.14e-2)" "unprognostic (2.47e-3)" "unprognostic (9.60e-2)" "unprognostic (8.14e-2)" "unprognostic (3.71e-1)" "unprognostic (1.82e-1)" "unprognostic (1.62e-1)" "unprognostic (3.02e-1)" "unprognostic (2.75e-6)" "unprognostic (3.19e-1)" "unprognostic (1.10e-1)" "unprognostic (1.61e-1)" "unprognostic (3.22e-2)" 2.0 1.5 0.2 11.5 0.2 38.0 2.3 0.4 0.5 1.8 0.6 4.0 6.4 1.0 1.1 1.7 0.9 4.8 0.6 0.1 0.2 0.6 2.0 7.5 20.3 0.5 0.2 0.6 1.3 0.3 0.3 0.8 0.4 1.0 4.3 0.4 1.3 0.6 0.3 0.9 8.6 1.6 0.2 13.2 5.2 1.4 0.6 20.0 0.7 0.2 13.5 4.2 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.9 0.4 0.0 0.7 0.0 0.4 69.3 0.1 0.2 0.0 0.0 0.0 0.1 0.5 6.5 0.0 10.0 0.0 0.0 0.2 27.7 21.1 5.7 0.0 2.8 0.2 5.1 10.6 17.2 0.1 15.7 10.3 0.2 20.1 15.7 0.0 0.1 0.0 1.2 6.7 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.0 5.0 16.0 0.3 0.4 0.5 29.2 6.6 37.5 11.1 28.4 0.1 15.8 4.8 25.0 17.0 1.3 20.1 9.9 8.4 13.6 8.7 7.4 5.0 12.1 2.4 11.0 0.6 5.2 14.5 7.3 0.2 0.2 0.4 0.5 0.1 0.2 0.5 0.2 0.4 0.2 0.6 0.8 2.2 0.0 6.5 0.7 67.4 2.5 0.2 0.0 1.2 0.7 2.2 2.4 0.8 0.0 0.2 1.8 2.1 0.1 176.0 2.2 0.0 0.1 0.4 0.7 0.5 1.7 0.0 16.6 3.2 0.6 0.3 2.2 12.8 1.0 27.8 0.0 0.4 0.5 7.1 0.0 2.5 1.2 0.0 17.3 26.8 1.0 0.0 26.4 3.6 2.8 14.4 0.0 108.1 0.0 1.7 0.5 0.8 0.0 79.6 0.3 4.3 0.1 2.2 0.5 13.1 0.6 1.4 0.4 0.6 0.3 2.7 0.1 151.2 0.0 2.2 0.3 PTPN7 "HEPTP, LC-PTP" ENSG00000143851 "Protein tyrosine phosphatase non-receptor type 7" P35236 1 202147013-202161588 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.7;lymphoid tissue: 31.1" "Cell type enhanced" "Detected in many" "B-cells: 46.8;dendritic cells: 112.7;granulocytes: 140.7;NK-cells: 99.9;Plasma cells: 63.9;T-cells: 127.2;Theca cells: 54.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 9.8" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "granulocytes: 24.9;NK-cells: 14.9;T-cells: 14.0" "Cell line enhanced" "Detected in some" "HEL: 54.1;HL-60: 118.6;HMC-1: 150.8;NB-4: 51.4;THP-1: 53.7;U-937: 84.0" "Region enriched" "Detected in single" 9 "basal ganglia: 6.1" "Region enriched" "Detected in many" 8 "basal ganglia: 13.3" "CAB009530, HPA019118" Approved Supported "Microtubules,Mitotic spindle,Cytosol" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Microtubules, Mitotic spindle" "CAB009530: AB_2173845, HPA019118: AB_1855755" "unprognostic (4.19e-3)" "unprognostic (1.08e-3)" "unprognostic (3.09e-2)" "prognostic favorable (1.52e-4)" "unprognostic (2.91e-2)" "prognostic favorable (1.84e-4)" "unprognostic (3.01e-2)" "unprognostic (3.16e-2)" "unprognostic (1.43e-2)" "unprognostic (4.84e-2)" "unprognostic (1.14e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (2.42e-8)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (2.70e-1)" "unprognostic (2.39e-2)" 1.3 4.2 0.6 10.2 9.8 39.7 0.7 1.0 1.8 0.8 0.5 2.2 4.5 1.1 0.0 1.5 0.6 3.2 0.5 0.6 1.2 1.3 1.1 2.5 20.8 2.3 1.5 0.3 0.4 0.1 0.3 0.5 1.8 0.8 2.7 0.0 1.3 0.6 0.1 1.2 5.6 1.5 1.4 9.9 2.4 8.3 2.9 31.1 0.8 0.5 20.8 3.2 0.6 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 12.6 0.0 54.1 0.0 0.0 0.0 118.6 150.8 0.0 0.0 0.0 0.0 0.0 0.1 40.0 2.3 5.0 0.0 0.0 16.3 51.4 0.0 0.0 0.0 2.4 0.0 39.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 53.7 0.3 0.0 0.5 0.0 0.1 22.8 6.3 33.7 0.1 84.0 0.1 17.9 1.5 24.9 13.7 1.5 12.5 2.6 9.2 14.0 2.9 3.2 6.7 8.2 9.9 14.9 0.6 3.8 12.8 4.5 0.6 9.8 1.0 1.8 0.6 1.2 2.3 1.5 1.8 1.4 2.9 2.5 3.2 3.2 5.1 3.3 46.8 2.3 1.3 0.1 0.0 2.7 1.5 1.8 0.7 1.5 0.7 0.0 0.0 0.5 112.7 0.5 0.0 0.5 0.6 0.9 0.8 5.6 0.0 35.5 0.7 0.0 0.2 2.2 1.5 0.7 140.7 6.7 3.6 0.4 15.4 0.0 0.7 0.1 0.0 11.2 31.2 2.4 5.3 21.3 8.8 1.0 10.4 3.8 99.9 1.0 4.6 0.1 0.1 2.2 63.9 0.6 0.2 0.7 0.1 3.7 0.0 0.9 1.1 0.8 0.7 0.5 2.4 0.8 127.2 54.6 0.5 0.6 PTPRB PTPB ENSG00000127329 "Protein tyrosine phosphatase receptor type B" P23467 12 70515870-70637440 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 215.9;Endothelial cells: 211.5;Hepatic stellate cells: 504.0;Microglial cells: 164.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 24.3;hTERT-RPE1: 19.7;HUVEC TERT2: 61.4;TIME: 90.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004782, HPA067868" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA 14000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cell Junctions" "CAB004782: , HPA067868: AB_2685911" "unprognostic (3.18e-1)" "unprognostic (2.99e-6)" "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (3.55e-2)" "unprognostic (1.77e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.91e-2)" "unprognostic (7.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" 26.7 9.4 16.0 4.7 14.1 0.1 18.8 12.3 12.1 12.8 7.1 10.9 7.5 12.3 4.4 6.8 10.8 14.7 23.2 10.1 12.4 22.5 16.7 35.7 3.2 15.9 14.2 4.0 6.2 7.8 4.7 32.6 18.1 6.3 11.1 1.4 3.3 8.0 17.1 4.1 9.3 18.1 12.4 30.0 6.2 2.5 19.0 3.0 14.8 38.8 3.4 7.7 5.3 11.9 4.4 0.3 1.9 0.2 0.0 0.1 0.9 0.9 4.2 2.2 5.2 0.1 3.4 1.7 24.3 0.6 0.4 15.2 0.2 0.7 7.8 1.3 0.7 0.4 1.7 1.1 0.2 0.7 0.0 0.1 0.7 6.1 0.0 19.7 61.4 0.0 3.6 1.0 1.3 0.0 0.1 0.0 2.3 4.4 0.9 0.1 1.6 0.9 11.3 1.8 0.0 0.8 1.6 0.0 3.5 0.4 0.0 1.5 90.3 0.9 0.9 0.4 5.4 1.1 0.9 0.8 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.0 14.1 12.3 12.1 10.1 12.4 15.9 14.2 18.1 12.4 19.0 11.9 215.9 0.0 13.2 2.0 3.1 3.7 0.8 1.0 0.0 7.1 0.9 0.9 12.3 11.5 1.3 3.7 0.0 0.0 2.0 12.8 0.0 1.5 4.6 2.2 0.7 211.5 0.0 16.0 52.5 0.9 0.0 7.3 1.5 4.0 25.2 0.5 504.0 4.7 0.4 5.0 68.8 6.4 0.0 20.0 4.6 3.0 1.2 1.2 5.4 164.9 0.0 0.4 0.0 2.5 2.9 12.2 11.1 0.0 0.1 0.8 3.2 0.1 0.2 0.9 0.0 6.4 5.2 0.7 0.7 0.9 1.6 0.0 1.0 1.8 6.8 0.7 PTPRF LAR ENSG00000142949 "Protein tyrosine phosphatase receptor type F" P10586 1 43525187-43623666 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Heparin-binding, Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 259.9;Extravillous trophoblasts: 290.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-BR-3: 314.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012710 Uncertain Approved "Golgi apparatus" "Intracellular and membrane" NA NA 160000000 "Cluster 37: Intestine - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "HPA012710: AB_1855933" "unprognostic (8.20e-2)" "unprognostic (2.41e-2)" "unprognostic (3.01e-2)" "unprognostic (9.17e-2)" "unprognostic (8.34e-2)" "unprognostic (1.11e-1)" "prognostic unfavorable (3.47e-4)" "unprognostic (4.59e-1)" "unprognostic (1.51e-1)" "unprognostic (4.97e-2)" "unprognostic (4.68e-2)" "unprognostic (7.07e-2)" "unprognostic (1.99e-2)" "prognostic favorable (7.03e-4)" "unprognostic (2.33e-1)" "unprognostic (3.19e-2)" "unprognostic (2.58e-1)" 91.7 11.9 47.1 14.0 48.4 1.8 57.4 22.3 45.6 36.3 4.7 79.5 70.5 28.0 71.9 101.7 70.5 30.4 7.6 45.3 39.9 27.7 107.2 35.4 4.7 33.1 43.6 22.1 56.8 31.1 23.5 55.7 33.1 67.3 51.4 24.7 101.7 43.1 2.7 107.9 78.5 35.0 30.4 4.0 49.7 9.4 45.6 29.6 23.8 3.4 26.2 40.0 51.2 37.4 165.6 76.5 49.0 58.0 11.2 0.6 274.3 92.1 36.1 73.9 62.6 82.0 214.9 0.4 25.6 40.2 59.2 124.7 57.5 200.7 89.1 2.0 72.1 1.0 48.7 75.3 33.8 1.2 1.3 11.3 113.2 106.4 174.9 92.6 111.5 7.7 25.4 7.1 27.5 94.0 1.2 1.3 75.9 89.8 21.0 57.2 86.9 3.7 28.3 241.5 73.3 28.0 90.8 314.0 11.8 128.8 91.5 17.3 88.2 1.6 116.5 7.5 126.1 3.1 2.7 0.4 7.4 3.9 233.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.1 48.4 22.3 45.6 45.3 39.9 33.1 43.6 33.1 30.4 45.6 37.4 2.3 157.0 101.1 39.2 2.3 62.8 51.3 67.4 52.9 33.5 146.3 102.9 7.6 130.1 74.9 86.5 43.8 64.3 1.4 259.9 0.0 147.4 4.9 80.6 17.2 7.7 100.9 8.0 40.6 120.8 290.1 19.8 93.8 70.6 5.1 72.8 10.4 159.6 14.1 185.1 16.1 171.7 50.8 4.9 5.8 8.5 6.8 3.4 12.4 7.5 2.9 27.2 2.1 16.6 68.1 165.0 124.7 7.2 1.8 68.0 208.1 13.9 128.3 31.0 0.0 15.8 18.5 9.0 37.5 107.5 91.4 66.2 3.9 9.6 142.5 78.7 PTPRK R-PTP-kappa ENSG00000152894 "Protein tyrosine phosphatase receptor type K" Q15262 6 127968785-128520616 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 889.9;Oligodendrocyte precursor cells: 313.1;Oligodendrocytes: 1278.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 1.6;naive B-cell: 2.9" "Lineage enriched" "Detected in single" 7 "B-cells: 2.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054056, HPA054822" Uncertain Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 13000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions" "Vesicles, Plasma membrane" "HPA054056: AB_2682359, HPA054822: AB_2682614" "unprognostic (3.15e-2)" "unprognostic (1.07e-2)" "unprognostic (5.79e-3)" "unprognostic (4.95e-3)" "unprognostic (1.89e-2)" "unprognostic (7.26e-2)" "unprognostic (3.27e-1)" "unprognostic (6.06e-2)" "unprognostic (2.04e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (1.46e-1)" "prognostic favorable (9.33e-5)" "unprognostic (2.10e-1)" "unprognostic (1.55e-1)" "unprognostic (2.59e-1)" "unprognostic (9.32e-2)" 10.7 4.2 13.4 9.7 20.6 0.2 25.6 16.7 18.6 13.5 8.6 27.3 32.8 12.1 8.2 9.7 14.9 32.5 12.4 15.9 14.5 14.9 29.6 19.4 6.9 16.8 16.7 15.1 26.2 10.2 7.0 21.8 17.8 18.9 27.6 4.6 15.3 19.0 5.9 12.2 28.5 15.9 14.5 7.9 30.5 2.2 16.4 10.2 11.7 9.9 8.7 20.9 12.3 29.8 17.3 16.7 10.9 1.0 24.9 31.9 11.0 43.6 86.3 18.4 16.6 28.8 15.0 0.1 13.4 40.7 50.8 49.0 10.2 35.9 26.7 50.3 19.4 0.3 23.6 45.7 29.7 0.0 1.7 23.9 35.4 35.9 49.6 50.8 54.0 14.7 0.0 1.1 49.3 33.6 26.6 0.1 11.9 34.5 22.6 94.8 21.7 3.1 51.1 33.4 43.8 0.1 45.2 55.6 2.7 12.4 14.6 1.1 86.9 30.0 18.4 54.8 42.2 0.7 6.0 0.0 38.1 0.0 31.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 2.9 0.1 0.3 0.0 0.2 0.0 0.0 0.1 0.1 13.4 20.6 16.7 18.6 15.9 14.5 16.8 16.7 17.8 14.5 16.4 29.8 39.2 25.6 33.5 155.7 17.5 63.5 88.1 45.2 60.3 7.3 56.6 26.5 22.2 101.5 44.1 18.4 4.2 24.8 0.8 75.2 0.0 63.2 4.6 30.6 11.5 46.6 43.9 0.0 889.9 61.3 4.1 28.6 77.5 77.5 1.3 13.4 11.4 40.9 6.4 10.1 55.3 44.2 8.2 1.6 8.8 2.7 17.1 2.2 17.8 200.5 1.7 5.1 0.0 313.1 1278.1 124.2 53.8 18.0 1.0 115.8 68.7 13.4 25.9 0.7 59.2 20.1 41.5 11.3 8.9 27.0 38.1 26.8 3.4 14.1 56.6 157.0 PTPRO "GLEPP1, NPHS6, PTP-oc, PTP-U2, PTPU2" ENSG00000151490 "Protein tyrosine phosphatase receptor type O" Q16827 12 15322257-15602175 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.8;kidney: 36.3" "Group enriched" "Detected in many" 7 "Excitatory neurons: 193.6;Inhibitory neurons: 231.1;Oligodendrocyte precursor cells: 126.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 8.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "GAMG: 9.9;NTERA-2: 5.8;SH-SY5Y: 6.1;THP-1: 2.7" "Region enhanced" "Detected in all" "olfactory bulb: 175.9" "Low region specificity" "Detected in all" HPA034525 Enhanced "Intracellular and membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA034525: AB_10669785" "unprognostic (3.68e-2)" "unprognostic (3.49e-1)" "unprognostic (9.64e-2)" "unprognostic (1.25e-2)" "unprognostic (7.87e-2)" "unprognostic (2.08e-1)" "unprognostic (5.93e-3)" "unprognostic (5.37e-2)" "unprognostic (2.03e-1)" "unprognostic (3.72e-2)" "unprognostic (2.00e-1)" "unprognostic (5.43e-2)" "unprognostic (4.89e-2)" "unprognostic (2.12e-1)" "unprognostic (1.99e-2)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" 1.8 0.8 8.7 3.0 9.4 0.2 0.8 0.0 10.3 1.3 0.1 10.4 1.7 4.8 1.4 0.4 1.0 1.2 0.5 9.8 8.9 36.3 1.3 6.8 3.1 2.2 3.3 0.4 0.4 0.3 2.4 4.4 5.3 0.5 26.8 7.5 0.5 0.8 0.3 0.4 2.0 6.6 0.9 3.4 0.8 0.5 9.5 1.2 0.3 0.5 3.2 1.5 0.4 2.9 0.0 0.1 0.3 0.1 0.2 0.0 0.2 0.0 0.0 0.5 1.3 0.0 0.0 0.1 0.1 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 5.8 1.2 0.0 0.0 0.0 0.0 0.1 0.2 1.5 6.1 0.9 0.0 0.1 0.1 0.1 2.7 0.0 0.0 0.3 0.0 0.2 0.4 0.0 0.3 0.0 0.1 1.2 0.0 6.0 0.0 0.0 12.3 0.0 8.9 1.7 0.4 8.5 8.6 2.8 1.2 0.1 0.1 12.7 10.9 1.4 3.2 8.7 9.4 0.0 10.3 9.8 8.9 2.2 3.3 5.3 0.9 9.5 2.9 0.2 0.0 0.5 7.5 7.0 0.3 1.3 0.5 0.0 25.2 0.0 0.1 0.7 0.0 1.8 16.5 0.0 0.2 4.0 3.9 0.0 0.4 0.0 0.8 0.2 1.1 3.6 0.0 193.6 0.0 0.2 0.9 0.0 0.6 0.0 0.0 1.1 0.2 26.1 25.2 231.1 8.3 0.0 21.1 10.6 0.6 0.6 10.5 0.0 17.8 13.8 0.6 1.0 126.7 6.3 0.1 9.8 0.4 1.0 0.1 0.1 0.2 0.0 4.8 0.0 2.1 0.7 0.6 1.1 0.1 0.4 0.3 1.0 0.1 22.4 0.8 PXN ENSG00000089159 Paxillin P49023 12 120210439-120265771 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 152.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 169.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003841, HPA051309" Supported Enhanced "Focal adhesion sites,Centrosome,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Focal adhesion sites" "Centrosome, Cytosol" "CAB003841: AB_562188, HPA051309: AB_2681436" "unprognostic (4.00e-2)" "unprognostic (1.94e-2)" "unprognostic (3.51e-2)" "unprognostic (3.55e-3)" "prognostic unfavorable (1.09e-4)" "prognostic unfavorable (3.72e-5)" "prognostic unfavorable (7.12e-5)" "prognostic unfavorable (1.73e-4)" "unprognostic (3.12e-2)" "unprognostic (9.19e-3)" "unprognostic (2.66e-2)" "unprognostic (1.73e-1)" "unprognostic (2.12e-2)" "unprognostic (3.35e-2)" "unprognostic (2.09e-1)" "unprognostic (1.98e-1)" "unprognostic (2.75e-2)" 83.1 60.9 28.7 49.1 30.8 81.4 74.4 27.6 30.5 64.5 33.7 69.0 55.7 56.3 18.7 30.9 72.3 38.2 84.2 28.0 28.5 70.2 29.5 84.6 29.3 37.1 30.8 28.5 34.5 27.8 29.5 73.3 30.3 58.9 49.9 61.8 49.4 40.6 119.2 45.6 61.1 44.5 31.8 72.5 47.5 26.5 36.6 25.9 58.1 46.1 18.4 75.8 53.2 29.2 182.4 87.5 31.3 30.1 60.4 158.1 206.1 151.8 128.6 118.9 61.5 102.5 108.9 12.2 94.6 154.9 115.1 126.0 21.7 272.0 93.0 9.9 18.6 2.3 63.8 37.9 86.8 2.7 3.6 76.5 176.2 125.3 143.9 139.7 211.6 32.2 32.4 19.5 239.3 119.6 11.1 4.1 43.5 77.1 300.8 26.2 51.0 10.8 121.4 171.9 48.7 14.5 133.2 40.3 81.7 72.1 96.1 14.8 289.9 78.9 86.7 103.6 183.9 20.4 12.3 4.6 228.9 27.0 159.2 40.8 44.2 49.2 84.5 15.7 45.3 1.7 38.4 56.0 26.2 1.1 29.5 40.3 169.6 51.8 0.8 4.1 31.4 60.6 28.7 30.8 27.6 30.5 28.0 28.5 37.1 30.8 30.3 31.8 36.6 29.2 93.6 57.7 27.9 11.8 3.0 42.3 40.6 32.8 15.4 7.8 20.3 22.9 14.7 22.8 33.3 42.3 33.3 40.8 61.6 83.1 19.6 31.6 2.1 26.0 16.7 71.0 54.6 6.1 5.1 40.2 152.4 29.7 37.2 28.8 18.3 6.2 62.2 17.2 34.2 11.8 7.7 52.7 24.4 42.3 23.7 2.8 24.2 23.5 26.6 19.7 36.8 9.1 99.9 13.0 9.2 84.8 51.6 18.8 14.5 41.7 56.6 14.6 40.0 33.6 6.6 16.7 12.1 3.5 9.1 8.1 19.5 25.0 34.4 11.3 35.8 42.6 PXYLP1 "ACPL2, FLJ23751" ENSG00000155893 "2-phosphoxylose phosphatase 1" Q8TE99 3 141228726-141367753 "Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 148.2" "Cell type enhanced" "Detected in many" "Early spermatids: 196.8;Late spermatids: 131.1;Spermatocytes: 95.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017243 Uncertain "Intracellular and membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA017243: AB_1844509" "unprognostic (9.55e-2)" "unprognostic (3.48e-3)" "unprognostic (1.81e-1)" "unprognostic (2.06e-1)" "unprognostic (8.45e-2)" "unprognostic (8.04e-3)" "unprognostic (4.05e-3)" "unprognostic (5.43e-2)" "unprognostic (1.27e-1)" "unprognostic (6.95e-2)" "unprognostic (5.07e-3)" "unprognostic (4.67e-2)" "unprognostic (1.29e-2)" "unprognostic (5.20e-2)" "unprognostic (1.37e-1)" "unprognostic (8.56e-2)" "unprognostic (8.17e-3)" 4.2 6.3 5.6 4.3 6.4 5.0 8.3 1.7 13.5 7.3 0.3 5.4 5.5 8.8 148.2 2.6 6.4 8.2 13.8 6.3 6.5 7.5 5.1 4.9 9.1 1.0 3.0 8.6 9.2 16.2 7.4 18.2 1.1 10.1 5.6 18.3 6.6 28.9 2.9 4.6 6.4 7.2 3.4 5.3 5.0 8.9 3.4 53.3 5.9 2.0 9.9 7.0 4.7 6.6 5.3 5.5 23.3 18.5 9.0 7.7 5.6 3.6 9.0 9.1 12.5 9.2 1.8 0.3 4.9 8.2 1.9 1.2 24.7 2.3 8.7 17.4 16.3 1.9 7.5 7.4 19.2 4.8 1.0 7.3 10.4 2.8 1.0 11.3 0.6 17.8 0.9 2.1 4.1 4.5 25.8 6.0 9.7 13.2 3.1 3.5 13.6 3.2 6.5 22.8 10.1 17.8 9.3 2.9 7.6 4.2 9.7 2.8 1.1 11.6 6.9 8.0 3.5 4.9 0.4 0.7 10.7 6.5 10.4 15.2 6.0 9.4 13.4 4.0 8.6 0.7 7.5 8.9 5.3 0.5 21.6 17.6 3.8 19.3 2.0 1.9 4.3 8.9 5.6 6.4 1.7 13.5 6.3 6.5 1.0 3.0 1.1 3.4 3.4 6.6 1.1 9.6 8.7 14.0 2.2 0.0 4.6 0.0 6.2 3.3 9.5 6.7 7.6 2.8 1.8 46.0 6.2 2.1 3.4 2.1 0.0 3.2 196.8 1.0 9.3 1.4 4.2 4.4 41.3 3.7 8.2 7.9 1.1 1.8 2.5 5.4 1.4 3.8 0.7 6.7 31.8 3.9 0.0 1.8 0.0 131.1 20.2 2.0 0.0 1.0 3.5 8.0 3.1 32.6 6.5 3.0 8.6 15.1 2.7 7.6 4.2 11.7 2.9 5.2 13.1 6.6 4.2 95.9 13.8 2.2 0.0 1.1 4.9 0.9 4.7 6.6 PYGO1 ENSG00000171016 "Pygopus family PHD finger 1" Q9Y3Y4 15 55538884-55588947 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 23.5;Endometrial stromal cells: 18.2;Inhibitory neurons: 30.4;Oligodendrocyte precursor cells: 59.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-698: 33.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042248 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm Cytosol "HPA042248: AB_10794272" "unprognostic (5.55e-2)" "unprognostic (9.82e-2)" "unprognostic (2.61e-2)" "unprognostic (4.54e-2)" "unprognostic (7.20e-2)" "unprognostic (1.61e-1)" "unprognostic (1.31e-1)" "unprognostic (8.23e-2)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" "unprognostic (2.68e-1)" "unprognostic (2.29e-1)" "unprognostic (6.72e-6)" "unprognostic (3.36e-4)" "unprognostic (4.84e-2)" "unprognostic (2.30e-2)" "unprognostic (1.80e-2)" 1.8 2.3 2.6 0.9 3.0 0.2 1.7 7.3 2.3 3.7 2.9 3.2 0.4 5.6 2.0 1.8 2.5 2.3 1.3 2.6 4.6 0.9 0.1 1.9 0.5 3.3 4.5 6.1 1.4 13.2 3.0 2.0 3.1 4.5 1.0 4.5 0.9 4.8 11.7 0.7 0.9 4.7 3.3 0.3 1.4 3.2 4.9 0.4 6.8 9.1 0.4 2.2 1.7 2.4 3.7 6.3 12.2 6.2 4.4 10.0 4.6 7.8 8.9 6.2 7.1 4.5 0.0 0.0 2.4 5.3 8.9 0.0 12.4 0.1 8.3 0.0 3.9 1.8 1.8 0.4 5.9 6.6 0.0 5.5 6.2 5.5 0.9 6.9 3.2 1.0 0.1 0.0 10.3 0.1 0.3 0.0 3.3 0.9 3.4 0.0 14.8 0.0 2.1 2.7 6.5 7.3 7.6 0.0 5.6 1.7 2.3 2.1 0.0 15.8 6.9 0.3 9.5 0.2 0.2 33.6 4.9 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.0 7.3 2.3 2.6 4.6 3.3 4.5 3.1 3.3 4.9 2.4 0.6 9.6 6.3 23.5 0.0 1.7 5.9 0.1 4.6 5.6 2.4 3.6 6.1 0.0 1.9 9.2 0.0 1.5 0.1 0.0 0.0 0.5 2.9 1.6 18.2 1.1 0.0 0.0 1.8 0.0 0.2 9.3 0.0 1.9 0.0 7.1 1.1 0.0 0.5 0.0 30.4 0.0 0.0 0.6 1.4 2.6 9.9 0.3 7.2 4.7 0.0 7.0 0.0 59.8 1.9 0.5 0.0 12.0 0.0 5.7 0.0 0.2 1.8 4.5 0.0 12.7 6.1 11.6 2.8 1.4 0.9 0.3 0.6 2.0 0.0 0.7 RAB39A RAB39 ENSG00000179331 "RAB39A, member RAS oncogene family" Q14964 11 107928448-107963482 "Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.9;lymphoid tissue: 3.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 4.2;Excitatory neurons: 5.2;Inhibitory neurons: 8.8;Microglial cells: 20.6;Spermatocytes: 6.4" "Cancer enhanced" "Detected in some" "testis cancer: 1.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "GAMG: 11.6;NTERA-2: 8.6;RPMI-8226: 15.5;SCLC-21H: 27.8;SH-SY5Y: 17.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042505 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA042505: AB_2678030" "unprognostic (1.45e-1)" "unprognostic (1.48e-2)" "unprognostic (1.83e-1)" "unprognostic (3.40e-2)" "unprognostic (4.99e-1)" "unprognostic (4.30e-2)" "unprognostic (4.26e-3)" "unprognostic (1.20e-1)" "unprognostic (5.55e-2)" "unprognostic (7.36e-2)" "unprognostic (4.22e-3)" "unprognostic (2.24e-2)" "unprognostic (1.41e-3)" "unprognostic (1.11e-1)" "unprognostic (1.36e-1)" "unprognostic (5.02e-2)" "unprognostic (2.43e-1)" 0.7 0.9 1.7 2.9 1.4 0.6 0.3 3.1 3.2 0.2 0.2 0.5 0.5 0.2 0.0 0.3 0.2 0.8 0.2 3.2 3.9 0.6 0.6 0.9 2.1 3.1 2.6 0.2 0.3 0.2 0.4 1.2 3.5 0.2 0.8 1.1 0.2 0.1 0.0 0.3 0.7 0.7 2.6 3.0 0.6 0.8 2.2 2.6 0.3 0.1 1.4 0.9 0.0 2.3 0.0 1.8 7.3 0.1 0.0 0.0 0.9 0.1 0.0 0.8 0.6 0.0 0.0 0.4 0.1 0.0 11.6 0.0 7.4 0.0 0.1 0.0 0.9 0.1 0.1 0.0 0.0 0.5 6.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 8.6 0.0 0.2 0.0 4.0 15.5 0.1 0.0 27.8 17.1 0.0 0.0 0.4 1.6 0.4 3.0 0.0 0.1 1.9 0.0 1.3 0.1 4.3 0.0 0.4 1.7 4.1 0.1 1.4 0.0 0.0 2.2 0.0 0.8 0.0 0.0 1.0 0.5 0.0 0.0 0.1 0.0 1.6 0.1 0.0 0.4 1.7 1.4 3.1 3.2 3.2 3.9 3.1 2.6 3.5 2.6 2.2 2.3 0.0 0.0 1.1 0.7 0.8 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.1 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 1.8 0.0 5.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 8.8 0.0 0.0 4.1 3.7 0.8 0.0 4.1 0.0 20.6 1.8 0.0 0.0 4.0 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.1 6.4 2.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 RAB4A "HRES-1/RAB4, RAB4" ENSG00000168118 "RAB4A, member RAS oncogene family" P20338 1 229271062-229305894 "Enzymes, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 32.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 32.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 32: Non-specific - Translation" "unprognostic (9.21e-2)" "unprognostic (7.58e-2)" "unprognostic (1.81e-2)" "unprognostic (2.09e-1)" "unprognostic (2.09e-2)" "unprognostic (1.21e-1)" "unprognostic (2.83e-1)" "unprognostic (8.53e-2)" "unprognostic (6.41e-2)" "unprognostic (3.85e-2)" "unprognostic (2.99e-2)" "unprognostic (2.47e-1)" "unprognostic (1.67e-2)" "unprognostic (1.45e-1)" "unprognostic (2.11e-1)" "unprognostic (4.26e-2)" "unprognostic (1.72e-2)" 12.1 12.9 29.7 7.6 27.4 7.2 19.4 27.9 35.7 19.4 24.0 17.9 17.0 12.5 13.4 17.7 15.2 15.0 38.5 24.5 27.3 15.8 30.8 10.9 10.9 25.7 31.4 15.6 24.7 14.3 9.1 11.3 26.0 34.3 19.1 17.3 38.8 20.9 34.2 16.9 13.4 13.4 25.7 7.8 26.7 11.4 34.3 12.4 19.8 35.0 11.8 15.4 13.9 27.7 10.3 13.8 22.6 15.7 31.7 35.1 18.9 15.4 18.3 9.2 8.8 25.6 16.8 0.0 25.1 20.7 7.7 11.1 15.2 21.6 12.9 13.1 30.7 13.9 11.8 40.2 20.5 28.2 10.9 27.1 30.4 6.4 8.9 27.1 20.8 14.9 14.8 0.0 16.1 13.3 14.4 18.8 20.4 63.1 19.1 4.6 3.6 7.2 48.6 24.4 19.4 25.3 12.7 19.1 27.6 11.9 18.1 49.5 14.6 0.0 7.3 14.6 21.4 11.9 11.8 0.1 6.4 23.9 21.8 21.4 5.5 32.7 2.2 6.5 2.2 3.0 2.9 2.9 6.8 3.7 1.8 2.4 1.2 2.2 4.2 3.8 3.7 3.5 29.7 27.4 27.9 35.7 24.5 27.3 25.7 31.4 26.0 25.7 34.3 27.7 43.9 16.0 22.1 37.5 48.4 137.0 155.0 135.3 153.1 29.4 82.3 88.8 91.7 154.4 60.5 44.1 47.9 77.7 61.1 81.9 113.5 89.0 158.0 81.7 45.7 45.3 48.6 52.0 23.6 115.4 88.5 47.2 68.3 47.1 24.8 41.5 52.5 119.2 67.8 30.3 24.2 82.6 79.3 78.4 96.3 169.4 46.6 76.0 64.0 16.9 80.4 33.2 50.4 23.6 38.0 84.9 105.7 83.8 47.6 145.2 73.0 128.1 63.2 58.4 46.0 41.6 46.0 92.6 35.2 83.8 122.6 58.0 50.5 39.5 110.5 161.9 RAB5B ENSG00000111540 "RAB5B, member RAS oncogene family" P61020 12 55973913-55996683 "Predicted intracellular proteins, RAS pathway related proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010224, HPA068337" Approved Supported Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "CAB010224: AB_2175453, HPA068337: AB_2685974" "prognostic unfavorable (2.24e-5)" "unprognostic (1.86e-1)" "unprognostic (1.91e-1)" "unprognostic (7.66e-3)" "unprognostic (2.09e-1)" "unprognostic (8.42e-2)" "unprognostic (9.16e-3)" "unprognostic (3.09e-1)" "unprognostic (3.13e-1)" "unprognostic (8.31e-3)" "unprognostic (8.64e-2)" "unprognostic (2.26e-1)" "unprognostic (2.27e-2)" "unprognostic (2.46e-2)" "unprognostic (2.74e-1)" "unprognostic (2.85e-1)" "unprognostic (2.49e-1)" 50.9 54.4 95.4 39.4 102.3 35.0 68.2 106.2 96.8 76.8 76.5 72.2 52.4 73.8 92.4 99.8 75.7 55.8 87.2 93.1 99.5 70.1 68.8 72.9 44.5 103.5 105.6 85.4 47.9 112.1 31.4 63.4 106.0 74.6 80.6 72.9 61.7 94.6 100.6 92.4 50.4 79.9 103.6 48.1 67.0 57.1 99.9 64.0 64.6 127.6 76.0 65.6 69.6 112.9 62.3 39.1 80.2 59.4 128.5 115.9 72.1 56.1 102.3 68.3 57.5 67.5 76.7 34.7 65.5 107.6 50.3 44.8 51.4 77.8 63.3 44.1 39.5 39.3 53.1 38.6 94.5 33.2 61.6 94.9 142.7 64.2 54.2 153.0 87.0 42.2 36.2 99.3 87.3 42.3 42.6 51.9 35.8 51.5 35.2 36.5 49.9 45.1 128.2 100.7 40.0 35.6 73.1 72.4 89.0 88.3 104.6 102.5 72.3 44.5 32.5 32.8 22.2 56.4 46.9 21.8 71.5 30.7 38.4 18.5 10.1 32.6 11.1 9.3 10.3 8.9 9.0 9.9 8.0 6.9 10.2 8.0 27.4 7.6 10.6 8.0 7.6 8.9 95.4 102.3 106.2 96.8 93.1 99.5 103.5 105.6 106.0 103.6 99.9 112.9 24.4 57.7 37.1 13.1 26.7 51.7 26.5 34.0 35.3 33.3 54.4 38.2 53.2 55.8 34.0 42.3 52.1 44.0 29.1 88.1 35.2 49.4 11.1 24.1 22.8 30.8 38.9 29.8 21.4 37.1 42.8 33.1 37.2 33.9 19.7 34.1 42.1 86.0 31.1 16.8 23.4 51.1 16.2 46.4 52.3 27.7 53.4 25.4 35.6 11.2 64.7 41.6 32.0 11.1 26.3 71.3 44.4 59.5 27.1 57.0 44.7 35.9 23.9 31.6 59.2 31.9 33.2 36.8 25.6 64.7 89.2 88.0 25.0 23.4 42.7 65.8 RABL6 "bA216L13.9, C9orf86, FLJ10101, FLJ13045, Parf, pp8875, RBEL1" ENSG00000196642 "RAB, member RAS oncogene family like 6" Q3YEC7 9 136807943-136841187 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 172.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044037 Uncertain Approved Centrosome,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Centrosome "HPA044037: AB_10966437" "unprognostic (3.10e-3)" "unprognostic (8.52e-3)" "unprognostic (1.20e-1)" "prognostic favorable (4.00e-4)" "unprognostic (9.23e-2)" "unprognostic (2.44e-2)" "unprognostic (1.90e-3)" "unprognostic (7.55e-3)" "unprognostic (1.65e-1)" "unprognostic (4.92e-2)" "prognostic favorable (1.46e-4)" "unprognostic (5.23e-2)" "unprognostic (1.03e-3)" "prognostic favorable (9.14e-4)" "unprognostic (4.08e-1)" "unprognostic (3.03e-2)" "unprognostic (2.15e-1)" 37.5 45.5 49.9 29.8 67.2 51.9 35.9 43.7 69.2 33.5 30.2 59.9 39.8 38.5 10.7 57.4 36.4 15.3 86.3 47.6 35.6 55.3 24.3 41.7 26.9 47.8 41.0 39.5 101.5 22.7 69.9 21.0 41.8 67.4 21.2 15.3 42.8 20.1 154.5 45.7 51.6 16.2 35.6 50.3 61.7 50.0 47.2 28.2 42.1 60.9 18.2 43.7 35.0 45.9 75.2 97.9 68.4 80.3 27.5 30.7 178.5 65.8 42.2 63.1 45.9 109.7 77.2 104.7 40.5 52.0 66.4 159.9 76.8 58.6 21.5 110.1 97.5 64.5 127.2 129.9 49.4 120.6 79.4 34.2 59.6 39.0 42.8 38.3 66.4 88.8 142.0 50.0 43.9 149.5 130.2 82.9 128.0 91.3 82.4 167.4 81.6 103.1 41.5 65.7 223.5 92.5 117.2 135.6 83.5 36.1 116.8 120.1 81.1 80.9 69.8 86.5 109.1 42.3 51.8 85.5 68.2 57.8 77.5 0.5 1.8 1.2 1.4 2.4 1.5 2.2 1.5 1.4 1.3 2.0 1.2 1.5 0.9 2.3 0.8 1.7 2.3 0.6 49.9 67.2 43.7 69.2 47.6 35.6 47.8 41.0 41.8 35.6 47.2 45.9 36.2 28.9 41.2 24.5 25.5 18.0 17.7 12.6 38.7 39.5 38.7 33.4 35.3 0.0 13.8 25.8 20.9 25.2 35.3 172.7 31.3 34.9 13.4 42.6 40.6 25.7 52.0 25.6 37.7 58.2 33.2 28.1 43.3 43.8 15.2 85.2 0.0 0.0 31.0 38.7 34.3 78.5 20.3 0.0 26.5 18.5 19.6 37.0 40.9 8.4 27.5 22.2 24.7 18.1 26.9 62.5 80.9 26.7 67.7 36.6 59.4 55.8 18.3 38.3 0.0 19.0 33.3 18.1 28.0 55.3 19.5 28.3 29.6 41.0 94.9 26.5 RAD23B "HHR23B, HR23B, P58" ENSG00000119318 "RAD23 homolog B, nucleotide excision repair protein" P54727 9 107283137-107332192 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 420.5;Late spermatids: 1201.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029718, HPA029720, CAB033868" Enhanced Supported Nucleoplasm,Cytosol No No 5900000 "Cluster 1: Neutrophils - Mixed function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "CAB033868: AB_1128418, HPA029718: AB_10600116, HPA029720: AB_10601008" "unprognostic (3.95e-3)" "unprognostic (1.01e-2)" "unprognostic (2.28e-2)" "unprognostic (8.14e-2)" "unprognostic (4.71e-2)" "prognostic unfavorable (2.58e-4)" "unprognostic (2.94e-1)" "prognostic unfavorable (6.71e-4)" "unprognostic (1.34e-1)" "unprognostic (3.72e-1)" "unprognostic (3.31e-2)" "unprognostic (1.20e-1)" "unprognostic (2.94e-3)" "unprognostic (2.69e-2)" "unprognostic (2.43e-1)" "unprognostic (7.49e-3)" "unprognostic (1.04e-1)" 73.8 47.8 26.6 44.4 27.0 82.8 48.5 40.4 37.4 42.8 22.0 47.7 41.9 41.9 68.8 63.6 40.9 34.1 48.7 29.0 29.2 44.4 140.8 39.3 39.4 26.9 27.0 37.8 64.5 50.4 30.5 77.7 26.3 48.2 47.7 42.1 38.4 43.5 153.0 64.7 40.6 55.0 22.5 36.2 41.5 59.4 27.7 58.4 42.6 123.5 49.9 67.5 42.8 30.7 132.9 114.9 158.6 102.9 107.5 166.6 179.9 200.6 162.3 172.8 116.9 190.1 140.5 184.8 79.3 218.6 156.4 181.2 221.0 175.9 172.9 126.4 73.0 96.2 112.0 147.6 140.3 174.2 79.3 141.1 161.3 165.3 248.0 136.0 124.3 79.6 158.3 133.6 159.5 215.0 169.6 88.3 170.5 231.2 133.0 125.3 209.6 87.8 149.8 122.1 144.9 98.2 138.8 193.1 125.8 237.5 197.7 70.5 114.3 129.0 127.0 161.6 152.5 91.9 181.2 98.5 138.0 101.7 138.0 0.9 1.1 1.1 1.9 1.2 2.1 1.8 1.1 1.6 1.0 2.1 1.7 1.5 2.9 2.3 0.8 1.1 2.2 0.6 26.6 27.0 40.4 37.4 29.0 29.2 26.9 27.0 26.3 22.5 27.7 30.7 49.7 44.8 40.4 32.3 54.7 195.5 148.1 40.5 79.1 40.5 65.3 36.6 117.4 68.6 42.2 35.0 27.1 269.7 37.1 82.9 50.9 89.2 420.5 69.8 80.8 68.7 101.0 76.1 54.9 77.4 259.7 79.3 60.6 90.8 36.2 83.0 55.6 209.9 99.5 50.5 47.2 83.8 38.7 65.6 131.1 1201.4 75.5 70.7 74.7 38.4 83.7 40.4 39.1 50.3 54.1 81.0 50.5 87.3 89.3 146.0 51.2 95.9 47.6 43.9 78.9 71.6 88.5 45.3 74.7 126.9 240.9 291.8 50.5 91.1 74.9 141.2 RAMP2 ENSG00000131477 "Receptor activity modifying protein 2" O60895 17 42758447-42763041 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 1066.8;Endothelial cells: 562.9;Hepatic stellate cells: 344.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 21 "plasmacytoid DC: 2.9" "Lineage enriched" "Detected in single" 21 "dendritic cells: 2.9" "Cell line enhanced" "Detected in many" "ASC diff: 120.4;EFO-21: 80.5;HUVEC TERT2: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052020 Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA052020: AB_2681697" "unprognostic (8.64e-2)" "unprognostic (2.12e-2)" "unprognostic (8.03e-2)" "unprognostic (1.16e-2)" "unprognostic (5.24e-2)" "unprognostic (4.13e-3)" "unprognostic (2.68e-2)" "unprognostic (1.04e-1)" "unprognostic (4.50e-2)" "unprognostic (5.18e-2)" "unprognostic (1.02e-2)" "unprognostic (6.79e-2)" "unprognostic (1.28e-2)" "unprognostic (6.96e-3)" "unprognostic (4.42e-2)" "unprognostic (2.20e-1)" "unprognostic (1.25e-1)" 190.0 29.0 60.4 19.2 61.8 0.1 168.9 61.7 72.3 100.7 67.7 35.7 12.5 63.1 27.8 25.1 51.7 39.6 123.2 59.3 65.8 70.5 16.7 163.3 26.2 65.7 68.1 33.0 17.1 23.8 20.8 97.0 72.7 42.1 21.1 4.1 45.9 27.5 43.3 55.9 44.1 72.6 62.7 40.2 33.9 11.9 66.6 11.4 71.7 98.7 24.5 45.9 49.6 62.4 0.1 1.1 4.9 0.1 120.4 6.2 4.0 0.9 2.1 10.2 4.9 11.5 0.1 0.0 80.5 3.0 0.5 0.0 4.6 0.1 8.9 0.0 0.2 0.0 0.7 3.7 3.0 0.0 0.0 4.2 0.1 1.8 0.4 3.5 37.6 1.5 0.1 0.2 0.6 0.0 0.6 0.8 23.3 0.0 0.0 0.1 0.1 0.0 0.6 0.6 4.8 9.8 2.9 0.0 17.3 4.8 1.2 3.2 6.7 19.3 7.1 0.4 2.4 0.0 0.1 0.3 0.0 0.1 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 60.4 61.8 61.7 72.3 59.3 65.8 65.7 68.1 72.7 62.7 66.6 62.4 1066.8 0.0 5.7 1.6 6.2 34.4 5.4 0.9 9.6 0.6 24.0 24.8 2.2 0.0 1.0 3.7 0.0 1.1 3.7 0.1 3.9 0.6 1.6 22.2 52.8 562.9 4.2 0.0 0.2 0.7 1.7 126.9 3.1 38.5 0.0 1.4 344.8 1.3 3.4 0.0 1.0 0.2 20.3 8.4 40.5 3.6 38.8 4.1 23.2 45.0 2.6 15.5 0.0 1.5 0.3 0.0 0.0 21.8 5.2 4.8 0.0 1.0 0.1 1.8 6.6 10.5 26.3 26.6 59.1 2.6 27.6 1.5 4.0 14.0 0.1 4.3 RAPGEF3 "bcm910, cAMP-GEFI, EPAC" ENSG00000079337 "Rap guanine nucleotide exchange factor 3" O95398 12 47734363-47771040 "Predicted intracellular proteins" Angiogenesis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 130.6;Astrocytes: 143.0;Collecting duct cells: 69.9;Endothelial cells: 53.0;Oligodendrocytes: 45.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 13.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 26.9;HUVEC TERT2: 12.1;NB-4: 14.3;RPTEC TERT1: 13.3;TIME: 12.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004386, HPA040365, HPA043518" Approved Uncertain "Endoplasmic reticulum,Cytosol" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Endoplasmic reticulum" "CAB004386: AB_627521, HPA040365: AB_2676941, HPA043518: AB_2678524" "unprognostic (2.12e-1)" "unprognostic (2.88e-2)" "unprognostic (2.99e-2)" "unprognostic (1.81e-2)" "unprognostic (1.88e-1)" "unprognostic (1.82e-2)" "unprognostic (1.23e-4)" "unprognostic (9.35e-2)" "unprognostic (1.25e-2)" "unprognostic (5.32e-3)" "unprognostic (4.67e-2)" "unprognostic (4.37e-2)" "prognostic favorable (6.67e-7)" "unprognostic (9.16e-2)" "unprognostic (2.92e-1)" "unprognostic (2.61e-3)" "unprognostic (3.38e-2)" 44.6 2.8 29.2 2.6 35.0 1.4 44.0 30.3 29.2 26.0 12.5 9.9 4.0 16.4 6.9 13.2 24.1 13.2 21.1 31.4 21.3 40.0 1.9 11.9 4.4 33.6 29.6 38.2 4.7 5.8 6.4 8.9 28.0 13.5 2.4 0.9 21.2 11.0 11.4 9.8 8.8 5.1 22.4 16.2 11.5 3.5 28.9 1.6 32.4 9.0 2.1 14.9 21.3 39.7 2.3 0.6 0.7 2.4 0.3 2.3 0.9 1.7 1.5 0.7 0.4 0.3 6.1 0.1 26.9 3.0 1.1 2.4 0.8 4.5 0.3 3.0 0.4 0.2 2.6 0.2 0.2 0.4 0.3 0.9 0.3 1.3 0.8 3.4 12.1 0.6 0.1 2.9 0.5 1.5 0.0 14.3 0.6 1.0 3.7 0.4 0.1 1.0 13.3 2.5 0.2 0.3 0.2 1.7 0.4 0.8 6.7 0.6 12.0 6.6 1.1 1.5 0.6 1.0 0.4 0.2 4.1 3.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.2 35.0 30.3 29.2 31.4 21.3 33.6 29.6 28.0 22.4 28.9 39.7 130.6 0.0 11.7 143.0 0.7 2.7 5.8 2.6 13.1 0.5 4.5 4.8 15.7 2.8 3.6 69.9 0.0 0.2 1.4 1.7 7.9 1.1 1.6 11.8 2.4 53.0 0.0 0.0 1.5 0.7 0.4 6.3 18.3 21.2 3.8 1.5 20.7 0.2 0.9 0.0 2.9 6.6 4.1 0.6 2.6 3.7 24.2 1.5 5.4 12.2 0.0 1.5 2.1 10.6 45.7 5.8 6.3 8.6 4.4 11.6 0.8 41.3 1.9 0.5 6.6 2.7 5.1 1.2 1.6 1.4 3.3 0.3 1.3 6.6 0.8 17.2 RAPGEF4 "cAMP-GEFII, CGEF2" ENSG00000091428 "Rap guanine nucleotide exchange factor 4" Q8WZA2 2 172735274-173052893 "Predicted intracellular proteins" Exocytosis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 142.3" "Group enriched" "Detected in many" 7 "Excitatory neurons: 441.1;Inhibitory neurons: 416.6;Microglial cells: 142.4;Oligodendrocyte precursor cells: 303.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 21.5;SCLC-21H: 8.3;U-266/70: 11.0;U-266/84: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004388, HPA028968" Approved Approved "Focal adhesion sites" NA NA "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Focal adhesion sites" "CAB004388: AB_670916, HPA028968: AB_2672846" "unprognostic (1.87e-1)" "unprognostic (4.22e-2)" "unprognostic (1.31e-1)" "unprognostic (2.98e-3)" "unprognostic (4.53e-2)" "unprognostic (1.20e-2)" "unprognostic (4.45e-2)" "unprognostic (1.80e-1)" "unprognostic (1.16e-1)" "unprognostic (3.23e-1)" "prognostic favorable (1.32e-4)" "unprognostic (6.32e-2)" "unprognostic (1.46e-3)" "unprognostic (1.97e-2)" "unprognostic (6.18e-2)" "unprognostic (5.70e-2)" "unprognostic (2.93e-1)" 5.3 45.6 105.0 1.8 113.1 0.2 6.8 69.8 141.6 6.1 49.1 2.1 2.4 5.6 3.1 2.6 3.4 4.7 7.5 142.3 77.7 5.3 34.6 11.4 2.0 61.2 75.0 13.1 4.5 4.0 6.2 2.6 60.8 4.1 1.6 18.8 2.4 3.3 1.5 14.9 2.3 5.4 55.7 0.6 7.7 4.7 128.3 2.2 5.5 1.7 2.0 5.3 3.2 121.9 0.1 0.2 3.2 0.5 0.1 0.3 0.1 1.1 0.7 0.1 0.3 0.0 3.7 0.0 0.2 0.0 0.2 0.7 2.8 0.7 0.3 0.2 5.9 0.6 2.8 0.0 0.0 3.2 0.9 0.1 0.9 0.0 0.0 3.2 3.5 1.6 0.0 21.5 0.1 0.1 0.2 0.2 0.4 1.8 0.4 0.1 0.7 0.0 0.0 6.6 8.3 3.0 0.1 0.1 1.1 1.6 0.1 0.1 1.0 0.1 0.3 0.0 0.3 11.0 23.0 0.0 0.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 105.0 113.1 69.8 141.6 142.3 77.7 61.2 75.0 60.8 55.7 128.3 121.9 14.7 3.2 2.8 23.2 1.9 6.1 1.1 0.1 2.8 3.5 5.5 3.9 6.9 0.0 0.0 0.0 45.9 0.1 0.1 0.0 0.0 1.7 2.5 1.2 0.2 32.4 7.8 0.0 441.1 2.7 0.1 4.8 3.1 0.9 0.0 3.3 23.9 11.8 0.1 1.7 416.6 0.5 0.0 1.2 2.1 1.4 4.4 0.2 3.6 142.4 0.0 1.3 0.0 303.1 28.4 1.5 0.1 1.5 1.6 0.5 0.0 0.0 0.0 9.2 0.0 0.4 1.2 0.7 4.1 1.6 3.8 0.1 0.6 4.2 0.1 0.7 RASAL1 RASAL ENSG00000111344 "RAS protein activator like 1" O95294 12 113098819-113136239 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Differentiation "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 59.8;salivary gland: 28.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 36.8;Excitatory neurons: 14.0;Gastric mucus-secreting cells: 57.1;Oligodendrocytes: 46.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 15.3;EFO-21: 19.3;REH: 22.3;RPMI-8226: 50.0;RPTEC TERT1: 19.0;U-698: 42.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041650 Enhanced Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 25: RPMI-8226 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" "Cell Junctions" "HPA041650: AB_2677598" "unprognostic (9.95e-2)" "unprognostic (1.11e-2)" "unprognostic (5.44e-3)" "prognostic unfavorable (3.26e-5)" "unprognostic (1.27e-2)" "unprognostic (7.73e-3)" "unprognostic (1.57e-2)" "unprognostic (1.43e-2)" "unprognostic (2.65e-1)" "unprognostic (3.02e-3)" "unprognostic (3.16e-2)" "unprognostic (2.53e-1)" "unprognostic (1.74e-2)" "unprognostic (2.85e-3)" "unprognostic (1.15e-1)" "unprognostic (3.34e-2)" "unprognostic (2.64e-1)" 0.0 15.4 10.9 1.2 13.8 0.5 1.0 0.5 19.1 3.5 1.1 1.7 0.4 0.1 0.1 22.6 1.6 0.3 0.0 23.6 4.0 17.2 0.1 0.2 1.1 1.7 4.3 0.0 1.1 59.8 5.0 0.2 1.8 0.2 1.1 0.5 28.5 3.9 0.0 11.4 0.5 0.0 0.6 0.2 10.6 0.7 7.7 0.2 10.1 0.0 2.7 0.2 5.3 12.1 0.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 3.9 15.3 19.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.3 0.0 4.3 0.0 0.0 0.6 5.5 0.0 22.3 0.0 50.0 19.0 0.0 0.5 0.0 0.0 7.2 0.0 0.1 2.9 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 42.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 13.8 0.5 19.1 23.6 4.0 1.7 4.3 1.8 0.6 7.7 12.1 0.0 0.0 0.0 1.3 0.8 0.5 0.0 0.4 0.0 0.5 2.4 2.0 4.3 2.8 1.0 36.8 0.0 1.1 0.0 1.9 0.0 1.4 0.1 1.8 0.6 0.3 1.2 0.0 14.0 0.0 0.2 0.3 57.1 4.6 2.5 0.0 0.0 0.0 0.4 0.0 1.0 4.8 0.0 0.0 5.5 0.2 0.0 1.2 1.8 0.0 1.0 2.7 0.0 0.0 46.5 5.2 3.3 0.0 0.6 0.0 0.1 5.2 0.5 0.0 0.0 0.0 0.2 0.1 0.7 4.6 1.1 1.2 0.4 0.1 3.3 0.6 RASEF "FLJ31614, RAB45" ENSG00000165105 "RAS and EF-hand domain containing" Q8IZ41 9 82979590-83063177 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 41.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 101.7;Gastric mucus-secreting cells: 356.8;Prostatic glandular cells: 106.4;Respiratory ciliated cells: 100.6;Urothelial cells: 107.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 53.2;RT4: 38.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021431, HPA078596" Approved Uncertain Microtubules NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" Microtubules "HPA021431: AB_1856087, HPA078596: " "unprognostic (1.22e-1)" "unprognostic (1.20e-1)" "unprognostic (1.73e-2)" "unprognostic (1.26e-1)" "unprognostic (2.59e-1)" "unprognostic (2.40e-2)" "unprognostic (9.91e-3)" "unprognostic (1.61e-1)" "unprognostic (1.20e-1)" "unprognostic (8.60e-2)" "unprognostic (1.66e-3)" "unprognostic (3.67e-1)" "unprognostic (1.41e-3)" "unprognostic (5.07e-2)" "unprognostic (6.05e-3)" "unprognostic (1.28e-1)" "unprognostic (3.61e-2)" 1.1 1.6 16.2 2.8 15.4 3.6 17.6 21.2 21.9 2.9 18.0 15.2 6.3 2.7 10.2 7.1 6.3 12.6 1.1 13.9 9.2 5.3 2.4 8.2 1.5 10.0 6.3 1.5 23.1 5.3 3.9 3.4 9.8 15.2 15.2 5.1 15.3 3.8 1.9 3.8 8.6 1.1 1.0 1.5 41.0 4.0 9.8 3.4 25.9 0.0 3.5 13.8 2.3 24.7 14.0 15.5 1.8 1.5 0.3 0.5 5.6 1.0 0.2 1.6 3.9 8.7 16.9 2.3 13.7 0.4 11.0 16.3 0.3 0.4 1.9 1.4 17.3 1.9 11.9 2.2 0.2 1.7 1.6 0.3 6.7 7.6 0.2 2.1 0.1 2.4 2.5 16.8 0.2 27.2 2.3 1.8 10.5 53.2 6.1 2.5 4.8 6.0 18.0 38.5 5.6 8.3 2.8 26.8 1.1 6.7 22.9 2.0 2.6 2.6 14.6 2.1 1.7 11.3 10.1 1.4 5.8 1.0 3.0 6.5 2.0 1.9 3.7 1.4 3.5 3.9 3.5 2.9 1.1 5.3 3.8 3.3 9.8 3.6 1.6 3.8 2.9 0.7 16.2 15.4 21.2 21.9 13.9 9.2 10.0 6.3 9.8 1.0 9.8 24.7 0.7 76.9 101.7 0.3 1.1 0.8 5.4 7.9 4.0 1.1 61.3 21.1 0.6 42.9 59.7 9.2 4.2 5.5 0.5 61.8 7.9 35.4 0.6 39.7 7.9 4.5 3.6 0.8 1.0 37.4 10.3 5.7 356.8 88.2 22.1 0.4 0.7 1.7 0.8 0.0 0.6 85.7 48.8 0.0 0.4 2.1 0.3 4.2 1.8 4.7 1.6 0.1 0.0 0.0 0.2 46.2 40.0 0.0 1.5 106.4 10.4 8.3 100.6 1.3 0.0 0.7 2.8 0.5 4.8 28.2 0.9 7.5 3.1 1.2 35.7 107.7 RBM19 "DKFZp586F1023, KIAA0682, Mrd1" ENSG00000122965 "RNA binding motif protein 19" Q9Y4C8 12 113816738-113966325 "Plasma proteins, Predicted intracellular proteins" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038860, HPA058732" Supported Supported Nucleoli NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 72: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 59: Non-specific - Transcription" Nucleoli "HPA038860: AB_10697400, HPA058732: AB_2683801" "unprognostic (2.10e-1)" "unprognostic (1.54e-1)" "unprognostic (3.61e-2)" "unprognostic (4.83e-3)" "unprognostic (1.50e-1)" "unprognostic (9.14e-2)" "prognostic unfavorable (5.87e-7)" "unprognostic (9.32e-3)" "unprognostic (2.61e-1)" "unprognostic (5.14e-2)" "unprognostic (4.43e-2)" "unprognostic (3.53e-3)" "unprognostic (8.37e-2)" "unprognostic (3.18e-2)" "unprognostic (2.22e-1)" "unprognostic (1.28e-1)" "unprognostic (2.06e-2)" 11.5 14.1 7.4 12.5 8.5 16.4 13.5 5.7 8.8 13.8 7.9 13.8 8.7 13.1 8.3 12.5 12.9 6.4 11.6 6.5 7.1 13.4 12.3 12.2 14.0 8.7 7.9 18.9 14.2 10.1 12.7 9.9 8.8 15.1 8.9 7.7 12.6 8.4 16.7 12.5 13.5 9.0 5.1 13.3 13.3 11.9 10.3 10.4 20.8 9.3 12.9 14.4 12.4 11.1 13.0 25.6 15.0 29.3 14.7 11.7 22.7 22.9 17.9 25.3 18.5 34.4 17.7 23.1 13.9 19.5 18.5 18.1 35.4 22.1 19.8 42.0 20.8 49.6 28.0 33.4 11.1 37.9 22.7 14.6 14.3 31.0 11.2 16.2 18.6 17.8 54.3 9.3 15.9 19.4 21.4 28.6 32.8 12.9 21.6 28.2 14.4 20.1 17.3 24.9 17.9 14.4 20.5 29.3 14.2 12.4 32.3 10.9 21.3 16.6 20.3 14.4 14.3 16.7 13.5 22.7 22.3 26.7 21.5 0.1 4.4 1.3 7.7 7.7 6.0 7.3 5.5 6.4 6.1 5.9 4.4 6.0 0.2 7.6 12.4 4.2 5.4 4.8 7.4 8.5 5.7 8.8 6.5 7.1 8.7 7.9 8.8 5.1 10.3 11.1 8.1 16.0 9.6 18.9 15.6 13.8 14.6 5.1 10.8 11.8 10.3 8.3 20.4 7.2 9.2 11.0 8.4 10.6 13.2 6.5 1.9 11.7 7.2 9.1 11.7 11.2 9.0 12.4 13.8 13.3 9.2 13.6 10.2 9.8 15.2 15.5 4.6 6.9 12.3 6.7 13.1 8.4 6.1 7.6 8.7 9.5 10.8 9.8 3.6 24.4 16.8 5.4 8.2 11.1 15.5 14.5 5.6 7.2 15.1 15.3 6.4 9.8 12.8 13.5 0.0 14.1 12.9 16.6 15.1 11.8 11.5 11.4 15.1 10.4 7.8 11.4 RBMS3 ENSG00000144642 "RNA binding motif single stranded interacting protein 3" Q6XE24 3 28574791-30010391 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 331.1;Inhibitory neurons: 655.9;Microglial cells: 1013.7;Oligodendrocyte precursor cells: 229.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 5.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "plasmacytoid DC: 3.9" "Lineage enriched" "Detected in single" 9 "dendritic cells: 3.9" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 20.7;WM-115: 24.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034719 Uncertain Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA034719: AB_10670172" "unprognostic (8.39e-2)" "unprognostic (2.54e-2)" "unprognostic (1.02e-1)" "unprognostic (7.08e-2)" "unprognostic (2.29e-1)" "unprognostic (1.33e-1)" "unprognostic (3.13e-2)" "unprognostic (4.95e-2)" "unprognostic (1.08e-1)" "unprognostic (3.90e-2)" "unprognostic (1.90e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (1.85e-4)" "unprognostic (2.25e-3)" "unprognostic (3.81e-2)" "unprognostic (8.48e-2)" "unprognostic (3.24e-4)" 15.8 8.6 6.5 2.1 7.2 0.1 12.2 9.5 5.8 9.9 12.0 8.1 1.4 6.2 6.7 3.1 9.8 6.7 14.3 2.1 21.4 5.1 3.7 12.6 2.7 12.6 15.7 11.6 2.0 4.9 3.2 10.4 9.0 6.4 2.6 0.4 4.7 8.7 6.4 3.8 4.0 4.5 6.3 6.6 4.3 2.2 11.1 5.5 15.3 10.8 1.7 8.1 7.3 2.6 2.2 0.2 10.2 0.1 19.6 12.5 0.0 5.7 3.6 5.9 6.8 0.0 0.4 0.0 6.1 20.7 1.8 0.2 0.5 3.8 10.9 0.0 1.1 5.9 8.7 0.0 19.9 0.1 0.0 11.8 2.6 10.5 12.3 8.4 7.9 0.0 0.0 0.0 7.4 0.0 0.1 0.0 0.3 0.0 0.4 0.4 7.5 0.0 2.2 0.0 0.0 19.4 13.7 0.0 0.7 4.6 0.0 0.0 17.1 11.1 11.6 13.5 11.7 0.0 0.0 0.8 1.5 0.0 24.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 3.9 0.3 0.0 6.5 7.2 9.5 5.8 2.1 21.4 12.6 15.7 9.0 6.3 11.1 2.6 100.9 118.6 18.8 331.1 0.6 8.3 25.5 23.0 2.2 0.4 2.7 19.8 16.2 31.5 21.3 9.2 0.0 16.4 5.9 0.0 0.0 5.3 35.1 2.8 7.0 54.4 0.0 0.0 20.7 1.2 3.0 96.8 2.0 4.6 5.1 19.8 129.9 1.9 2.8 0.0 655.9 0.0 6.1 30.3 14.1 18.8 159.7 2.7 7.2 1013.7 0.6 0.0 0.0 229.2 8.9 0.4 0.0 110.6 0.1 24.3 0.0 2.9 10.5 0.0 111.7 154.6 73.5 1.2 1.5 2.4 7.2 9.6 2.9 22.4 0.0 4.7 RBP1 "CRABP-I, CRBP, CRBP1, CRBPI, RBPC" ENSG00000114115 "Retinol binding protein 1" P09455 3 139517434-139539829 "Metabolic proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 1366.7;pancreas: 632.7" "Group enriched" "Detected in many" 4 "Granulosa cells: 5988.6;Theca cells: 3228.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "SH-SY5Y: 835.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 64.4" "HPA007338, CAB018603, CAB019276" Enhanced Approved Nucleoplasm,Cytosol NA NA 41000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Cytosol Nucleoplasm "CAB018603: AB_2060572, CAB019276: , HPA007338: AB_2667814" "unprognostic (9.62e-3)" "unprognostic (7.67e-2)" "unprognostic (9.53e-3)" "unprognostic (5.17e-1)" "unprognostic (7.48e-3)" "unprognostic (2.27e-2)" "unprognostic (6.29e-2)" "unprognostic (1.16e-1)" "unprognostic (7.12e-2)" "unprognostic (3.91e-3)" "unprognostic (2.74e-2)" "unprognostic (8.86e-2)" "unprognostic (1.11e-3)" "unprognostic (2.60e-2)" "unprognostic (1.71e-1)" "unprognostic (4.50e-2)" "unprognostic (1.28e-3)" 23.7 377.1 64.6 18.4 65.2 1.3 49.5 64.9 72.7 53.8 251.4 30.3 32.3 180.2 64.2 35.4 390.2 182.9 60.1 65.5 67.8 46.9 140.8 26.8 18.6 83.1 69.0 1366.7 632.7 46.8 257.8 63.6 64.7 44.8 14.2 23.2 50.2 41.3 15.2 31.3 26.2 119.3 68.2 47.0 29.3 56.1 75.2 9.4 23.0 15.5 12.0 65.7 24.3 67.5 7.8 2.9 7.4 164.2 0.3 0.0 0.9 0.1 0.0 0.0 0.1 0.4 76.1 0.0 53.8 0.1 2.6 0.1 38.2 0.5 0.0 0.1 5.3 0.1 2.7 75.5 155.1 0.2 0.1 3.0 0.0 0.1 0.0 160.9 0.0 0.0 0.2 29.9 0.2 0.0 0.2 0.5 18.4 0.2 0.0 0.1 32.0 0.5 0.1 0.1 19.6 835.4 35.3 0.1 0.1 13.9 3.2 1.1 0.0 0.3 120.0 0.2 0.3 0.6 0.5 0.5 1.3 0.0 2.3 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 64.6 65.2 64.9 72.7 65.5 67.8 83.1 69.0 64.7 68.2 75.2 67.5 24.8 32.1 5.9 8.8 3.5 17.6 53.5 91.9 2.8 26.3 70.4 47.8 21.4 77.2 30.3 23.9 2.1 3.2 1.0 0.1 13.7 1013.0 4.8 199.6 961.4 103.8 43.1 13.5 0.5 1042.7 6.2 158.8 19.9 58.1 0.0 5988.6 343.7 6.9 16.5 3.3 0.3 2.3 42.7 10.6 3.4 16.2 27.1 25.1 8.8 5.6 13.5 159.9 0.0 4.0 16.0 563.0 0.0 4.5 2.9 56.6 2.6 4.7 10.3 7.2 26.3 220.9 534.7 11.6 4.9 6.2 34.9 3.8 10.2 3228.5 2.7 32.7 RDH11 "ARSDR1, MDT1, SDR7C1" ENSG00000072042 "Retinol dehydrogenase 11" Q8TC12 14 67676800-67695793 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Cataract, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 582.0" "Cell type enhanced" "Detected in all" "Hepatocytes: 241.8;Muller glia cells: 299.7;Prostatic glandular cells: 285.7" "Cancer enriched" "Detected in all" 13 "prostate cancer: 286.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB046011 Enhanced "Intracellular and membrane" NA NA 340000 "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 5: Muller glia cells - Visual perception" "CAB046011: AB_11129613" "unprognostic (1.38e-1)" "unprognostic (6.86e-3)" "unprognostic (1.77e-1)" "prognostic favorable (2.62e-4)" "unprognostic (6.06e-2)" "prognostic unfavorable (2.89e-5)" "unprognostic (9.29e-2)" "unprognostic (1.98e-1)" "unprognostic (1.05e-1)" "unprognostic (3.58e-2)" "unprognostic (2.91e-2)" "unprognostic (1.27e-1)" "prognostic favorable (1.30e-7)" "unprognostic (1.65e-1)" "unprognostic (1.68e-1)" "unprognostic (2.18e-1)" "unprognostic (4.74e-2)" 23.6 59.5 39.3 24.5 43.2 13.9 28.7 50.2 54.4 32.6 35.9 29.2 34.1 33.2 86.0 34.6 23.5 42.7 17.6 40.4 47.2 106.0 153.1 34.9 20.4 49.2 47.7 28.9 42.6 79.8 23.4 21.9 49.3 582.0 31.4 73.9 44.2 34.4 8.3 31.4 23.9 43.6 49.8 22.2 31.9 28.4 46.1 30.7 61.7 13.5 26.2 34.3 30.3 58.4 183.7 81.9 71.3 82.0 111.5 100.4 59.3 68.0 134.2 83.7 150.9 68.6 216.7 31.7 51.2 64.6 104.8 142.5 104.0 150.8 113.7 63.0 42.6 65.1 40.7 69.0 106.9 24.3 46.0 94.4 98.0 109.3 92.0 63.9 97.4 87.0 52.1 101.1 77.2 97.5 72.2 38.8 40.4 49.7 92.8 53.6 87.4 45.8 194.1 93.0 73.8 62.0 71.2 89.7 99.1 58.2 100.7 38.3 74.2 89.5 101.1 38.9 49.5 47.5 40.0 40.7 115.8 66.0 74.3 282.4 71.1 104.0 62.3 57.7 68.2 39.0 67.7 61.5 51.3 45.5 67.3 64.8 11.0 56.3 65.4 59.1 65.1 115.8 39.3 43.2 50.2 54.4 40.4 47.2 49.2 47.7 49.3 49.8 46.1 58.4 27.0 25.6 66.0 38.2 29.2 11.5 40.0 77.9 16.5 53.5 45.4 24.5 20.4 68.6 59.9 47.8 50.1 24.9 32.4 26.8 7.9 92.5 2.5 21.9 50.9 39.3 43.3 29.2 33.3 84.0 38.1 37.5 19.9 38.2 29.2 46.3 47.8 241.8 35.8 79.1 37.6 28.9 89.5 42.4 15.4 6.1 43.2 35.9 35.6 17.8 39.8 299.7 37.0 70.4 43.4 61.2 36.7 56.1 27.3 285.7 17.5 56.0 23.9 97.0 46.0 29.7 38.7 25.8 24.0 20.2 19.2 63.5 29.8 66.7 25.3 46.1 REEP1 "C2orf23, FLJ13110, SPG31, Yip2a" ENSG00000068615 "Receptor accessory protein 1" Q9H902 2 86213993-86338083 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 86.2;Inhibitory neurons: 95.5;Oligodendrocyte precursor cells: 39.2" "Cancer enhanced" "Detected in many" "glioma: 7.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 68.1;HAP1: 15.0;RPMI-8226: 16.0;SCLC-21H: 32.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058061 Enhanced NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA058061: AB_2683591" "unprognostic (1.94e-2)" "unprognostic (1.61e-3)" "unprognostic (2.03e-2)" "unprognostic (2.60e-1)" "unprognostic (2.29e-2)" "unprognostic (5.10e-2)" "unprognostic (6.63e-2)" "unprognostic (9.07e-2)" "unprognostic (1.53e-1)" "unprognostic (1.21e-1)" "unprognostic (6.15e-2)" "unprognostic (2.35e-1)" "unprognostic (2.56e-2)" "unprognostic (6.77e-2)" "unprognostic (2.94e-2)" "unprognostic (1.19e-1)" "unprognostic (1.07e-3)" 4.7 6.2 17.0 1.8 15.8 0.0 4.9 4.1 30.4 3.9 11.5 42.4 4.4 18.9 3.7 6.2 13.6 3.8 16.6 15.4 44.0 2.0 1.1 3.6 0.5 24.6 38.1 1.9 9.9 7.9 13.9 2.2 50.0 7.3 5.0 12.9 1.6 12.9 19.8 2.0 9.3 20.7 4.4 2.0 8.8 44.5 18.7 0.3 2.0 14.3 0.6 21.7 5.8 14.3 0.0 0.0 2.2 2.9 0.1 0.0 68.1 0.0 0.0 4.5 0.5 2.5 0.0 0.0 3.2 0.0 3.4 4.9 15.0 0.1 3.9 0.0 8.1 0.0 5.0 0.4 0.0 0.3 0.4 0.7 0.1 0.1 0.0 0.0 0.0 3.0 0.0 0.0 0.1 2.7 0.1 0.0 2.6 0.1 0.0 0.1 6.5 16.0 0.3 0.3 32.0 3.1 3.5 1.6 0.2 1.3 5.1 0.9 0.0 0.0 2.3 1.3 6.3 7.2 5.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 15.8 4.1 30.4 15.4 44.0 24.6 38.1 50.0 4.4 18.7 14.3 1.7 9.6 0.5 14.7 0.2 2.0 0.3 0.3 0.0 10.0 3.6 1.1 23.0 2.8 2.8 0.0 2.1 2.4 0.0 0.4 1.9 3.5 18.0 17.1 0.3 5.7 4.8 0.0 86.2 6.2 26.6 2.4 0.0 0.7 0.0 0.8 12.5 0.2 0.9 3.3 95.5 0.2 8.2 0.8 1.6 14.4 2.5 0.4 1.8 6.5 0.6 13.4 0.0 39.2 6.0 6.5 0.0 3.4 0.0 1.6 0.0 5.1 16.6 15.8 19.7 4.2 13.5 4.0 2.7 0.5 1.1 6.6 0.2 0.0 0.5 0.4 REEP5 "C5orf18, D5S346, DP1, POB16, TB2, Yip2e" ENSG00000129625 "Receptor accessory protein 5" Q00765 5 112876385-112922289 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003895, HPA069960" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 6: T47d - Mammary gland" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" "HPA003895: AB_1845723, HPA069960: AB_2686221" "unprognostic (3.26e-3)" "unprognostic (2.60e-1)" "unprognostic (2.71e-1)" "prognostic favorable (5.23e-6)" "unprognostic (8.29e-2)" "unprognostic (1.44e-2)" "unprognostic (1.13e-1)" "unprognostic (8.41e-2)" "unprognostic (2.85e-1)" "unprognostic (3.75e-2)" "unprognostic (7.75e-2)" "unprognostic (5.90e-2)" "prognostic favorable (2.05e-5)" "unprognostic (2.88e-2)" "unprognostic (4.14e-2)" "unprognostic (1.83e-1)" "unprognostic (3.24e-2)" 76.9 105.4 97.1 50.5 100.2 27.3 130.6 92.7 120.7 87.1 76.8 66.6 56.8 58.4 120.0 52.1 64.7 60.8 133.2 107.3 110.5 148.0 124.3 80.4 48.2 112.2 104.8 72.2 123.0 140.7 41.5 66.6 115.2 98.9 58.1 81.5 147.7 84.2 114.3 59.1 58.1 55.0 96.4 54.3 70.2 28.3 120.0 32.1 239.4 99.6 56.7 73.2 49.1 98.3 101.7 90.9 29.7 72.5 136.0 115.9 104.7 102.2 92.6 96.4 103.4 74.9 138.1 42.5 179.6 105.1 112.5 107.5 66.8 138.9 88.5 190.6 116.4 42.8 56.3 63.5 126.8 36.9 77.4 81.3 136.0 82.2 78.0 94.5 113.7 38.7 26.0 84.5 121.3 100.0 15.7 60.7 43.4 73.5 75.3 22.4 84.3 116.6 229.1 108.4 56.9 43.1 148.5 244.6 99.8 75.5 287.3 58.9 142.4 83.4 32.0 126.5 126.4 97.6 126.2 33.8 142.6 65.4 47.8 224.4 222.9 234.3 140.1 249.5 149.4 175.7 112.7 133.9 189.0 149.2 52.5 94.6 253.0 112.7 316.2 133.6 177.9 236.4 97.1 100.2 92.7 120.7 107.3 110.5 112.2 104.8 115.2 96.4 120.0 98.3 141.2 166.7 102.3 30.0 131.1 93.0 177.7 291.6 89.4 83.5 225.3 188.1 217.3 145.8 213.7 195.0 89.6 296.0 138.4 77.0 82.2 275.1 231.5 111.8 97.0 130.5 118.0 34.9 78.6 414.1 352.8 182.3 65.7 141.6 108.9 76.0 118.2 197.0 267.1 87.5 95.0 127.5 256.3 135.0 159.9 42.0 116.2 168.8 206.3 36.5 188.6 97.2 101.0 44.7 71.5 316.5 141.1 133.9 271.6 225.3 134.1 146.1 170.6 80.0 111.7 92.6 253.0 162.8 63.9 118.1 101.6 489.8 123.7 100.3 104.5 214.8 REPS2 POB1 ENSG00000169891 "RALBP1 associated Eps domain containing 2" Q8NFH8 X 16946658-17153272 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 117.9;Inhibitory neurons: 142.7;Oligodendrocyte precursor cells: 84.9;Oligodendrocytes: 204.0" "Cancer enhanced" "Detected in all" "prostate cancer: 13.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 16 "basophil: 5.8;eosinophil: 4.5;neutrophil: 14.3" "Lineage enriched" "Detected in single" 28 "granulocytes: 14.3" "Cell line enhanced" "Detected in some" "HDLM-2: 30.2;Karpas-707: 11.7;RH-30: 8.4;RPMI-8226: 9.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000565, HPA026073" Uncertain "Intracellular and membrane" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 68: Epididymis - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA000565: AB_1079800, HPA026073: AB_1856176" "unprognostic (6.58e-2)" "unprognostic (2.14e-1)" "unprognostic (3.35e-2)" "unprognostic (7.83e-2)" "unprognostic (4.23e-2)" "unprognostic (3.70e-3)" "prognostic favorable (5.36e-4)" "unprognostic (4.85e-2)" "unprognostic (2.87e-2)" "unprognostic (5.53e-2)" "prognostic unfavorable (3.24e-4)" "unprognostic (1.83e-1)" "prognostic favorable (4.08e-4)" "unprognostic (5.89e-2)" "unprognostic (1.03e-1)" "unprognostic (2.43e-2)" "prognostic favorable (4.56e-4)" 2.4 11.1 7.6 1.2 9.4 3.0 3.3 2.4 29.1 15.9 1.6 4.3 2.1 4.2 12.6 1.3 2.1 2.1 1.6 11.2 9.2 11.0 7.6 4.6 0.5 2.4 4.4 4.0 10.3 9.4 6.0 2.6 3.4 8.2 4.6 9.3 5.1 7.8 0.9 0.9 2.0 4.2 0.9 1.2 6.3 2.1 9.3 0.7 2.0 1.3 0.6 1.8 0.9 12.5 1.4 0.6 0.0 0.1 0.8 0.5 0.1 0.0 0.0 0.1 0.2 0.1 5.2 0.0 0.6 0.0 3.9 0.2 1.1 2.8 0.5 30.2 0.6 0.0 0.7 0.0 0.7 0.0 0.1 5.3 0.9 0.0 4.7 4.9 1.6 0.0 0.0 11.7 0.3 1.4 0.0 0.4 0.2 4.3 0.9 0.0 8.4 9.4 0.3 2.8 4.2 0.3 2.2 2.1 1.7 1.7 3.9 0.2 0.2 0.0 0.2 0.1 0.4 0.5 0.0 0.4 0.0 0.4 0.2 5.8 0.3 4.5 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 14.3 0.0 0.2 0.3 0.0 0.1 7.6 9.4 2.4 29.1 11.2 9.2 2.4 4.4 3.4 0.9 9.3 12.5 11.7 32.1 13.5 6.5 0.9 0.6 9.6 4.4 1.2 49.5 7.9 5.5 6.6 4.3 8.8 14.7 0.0 0.2 1.5 10.4 1.9 3.0 0.2 7.1 4.0 2.3 9.5 4.4 117.9 14.6 9.1 4.1 9.7 9.6 0.0 7.9 4.2 15.1 4.2 38.7 142.7 7.8 0.0 5.7 6.4 0.9 9.3 6.6 1.8 21.5 4.9 0.9 0.0 84.9 204.0 7.9 5.1 12.8 1.3 10.6 2.3 11.6 2.7 2.6 0.0 0.8 2.0 0.7 2.6 0.9 1.3 0.7 0.5 16.3 10.2 6.5 RERG MGC15754 ENSG00000134533 "RAS like estrogen regulated growth inhibitor" Q96A58 12 15107783-15348675 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 104.7" "Cell type enhanced" "Detected in many" "Astrocytes: 202.7;Breast glandular cells: 80.1;Inhibitory neurons: 94.3;Sertoli cells: 92.1;Smooth muscle cells: 80.2" "Cancer enhanced" "Detected in all" "breast cancer: 19.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 15.2;BEWO: 34.1;T-47d: 66.0;U-2 OS: 21.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041387 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center" "HPA041387: AB_10796669" "unprognostic (5.33e-2)" "unprognostic (1.05e-1)" "unprognostic (7.72e-2)" "prognostic unfavorable (7.56e-4)" "unprognostic (8.72e-2)" "unprognostic (9.42e-3)" "unprognostic (2.47e-1)" "unprognostic (2.38e-2)" "unprognostic (1.85e-3)" "unprognostic (2.76e-2)" "unprognostic (5.07e-2)" "unprognostic (2.69e-1)" "unprognostic (7.16e-3)" "unprognostic (2.61e-3)" "unprognostic (3.30e-2)" "unprognostic (3.50e-1)" "unprognostic (2.58e-2)" 30.7 45.4 8.9 6.8 21.0 0.0 42.5 5.9 16.3 32.0 3.5 37.0 4.1 104.7 50.3 15.1 72.7 11.2 14.0 10.2 12.3 37.0 2.5 16.5 4.3 20.7 12.8 29.0 9.8 4.8 1.4 33.3 21.2 17.0 9.3 0.8 10.2 77.5 5.4 10.2 18.0 83.9 7.7 31.4 20.1 9.0 12.8 2.6 5.8 5.8 2.7 17.4 20.0 9.0 0.0 1.6 0.3 15.2 6.0 0.3 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 6.9 0.0 0.1 0.0 0.2 0.2 0.0 0.0 4.3 0.1 5.9 0.0 4.7 0.0 1.9 0.8 1.0 0.0 2.3 0.0 0.0 0.0 0.6 0.0 1.4 0.7 0.2 0.3 1.7 0.0 0.9 0.1 0.0 0.2 5.8 0.3 0.1 2.2 2.5 2.6 0.0 1.0 66.0 0.0 0.0 0.9 21.5 0.4 0.0 0.1 5.7 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 21.0 5.9 16.3 10.2 12.3 20.7 12.8 21.2 7.7 12.8 9.0 10.7 0.0 2.2 202.7 0.4 3.8 8.6 0.9 6.2 1.3 80.1 36.2 1.0 5.7 4.0 7.3 0.0 12.0 0.7 0.0 15.6 9.8 20.9 6.5 9.8 6.0 1.8 0.0 20.2 9.8 14.6 28.7 2.6 1.0 0.0 0.1 2.2 0.0 2.1 3.3 94.3 0.0 18.3 0.0 2.3 16.1 22.1 1.1 7.2 41.2 0.0 5.0 0.0 3.0 1.1 2.2 0.0 32.0 0.0 3.5 0.0 33.7 0.1 0.5 92.1 8.2 80.2 8.3 15.0 12.6 5.5 14.0 1.2 16.1 0.0 5.8 RETN "ADSF, FIZZ3, RETN1" ENSG00000104918 Resistin Q9HD89 19 7669049-7670455 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Hormone "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 247.2" "Group enriched" "Detected in some" 6 "Hofbauer cells: 118.2;Kupffer cells: 47.0;Macrophages: 90.4;monocytes: 58.2" "Group enriched" "Detected in many" 4 "lung cancer: 2.6;pancreatic cancer: 4.8;thyroid cancer: 1.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "classical monocyte: 170.4;intermediate monocyte: 91.7;myeloid DC: 118.7;non-classical monocyte: 47.4" "Group enriched" "Detected in many" 11 "dendritic cells: 118.7;monocytes: 170.4" "Group enriched" "Detected in some" 11 "NB-4: 524.3;U-937: 243.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted to blood" NA NA 5120000 1200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (5.61e-2)" "unprognostic (6.20e-3)" "unprognostic (1.32e-2)" "unprognostic (3.04e-1)" "unprognostic (5.19e-4)" "unprognostic (1.53e-4)" "unprognostic (7.34e-2)" "unprognostic (3.35e-2)" "unprognostic (9.30e-2)" "unprognostic (1.35e-2)" "unprognostic (1.20e-1)" "unprognostic (4.02e-1)" "unprognostic (7.16e-5)" "unprognostic (4.23e-2)" "unprognostic (2.26e-1)" "unprognostic (8.91e-2)" "unprognostic (1.20e-1)" 3.4 1.0 0.1 5.2 0.1 247.2 1.4 0.0 0.9 0.6 0.0 0.8 6.1 0.7 0.0 0.5 2.4 0.3 2.3 0.4 0.1 1.7 3.3 34.0 0.1 0.1 0.1 0.4 0.9 0.1 0.5 1.1 0.1 1.0 0.2 0.0 1.1 0.0 0.6 0.7 0.7 4.3 0.0 53.3 1.0 0.2 0.0 4.0 0.8 0.0 0.0 0.6 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.7 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.9 524.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 243.2 0.0 0.1 170.4 0.1 0.4 91.7 1.2 0.0 1.9 1.5 118.7 0.1 4.4 9.0 13.6 0.3 47.4 4.5 0.0 64.3 0.1 0.1 0.0 0.9 0.4 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 12.8 9.9 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.0 0.0 1.1 0.6 0.0 0.0 3.8 0.0 0.4 0.1 118.2 0.0 0.0 0.0 0.0 47.0 8.7 0.2 0.0 90.4 0.0 0.0 58.2 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.1 0.0 0.5 1.5 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.1 2.2 0.0 0.0 0.1 RFTN2 "C2orf11, FLJ30574, Raftlin-2" ENSG00000162944 "Raftlin family member 2" Q52LD8 2 197568224-197676045 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 70.9" "Group enriched" "Detected in many" 7 "Astrocytes: 152.8;Early spermatids: 125.0;Late spermatids: 351.7;Oligodendrocyte precursor cells: 198.5;Oligodendrocytes: 320.6" "Cancer enriched" "Detected in many" 5 "glioma: 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 19.8;ASC diff: 15.5;ASC TERT1: 8.7;HSkMC: 10.7;TIME: 6.4;WM-115: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035232, HPA043190" Approved Approved "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA035232: AB_10601495, HPA043190: " "unprognostic (1.15e-1)" "unprognostic (3.52e-1)" "unprognostic (2.07e-2)" "unprognostic (1.00e-1)" "prognostic favorable (8.05e-4)" "unprognostic (1.89e-2)" "unprognostic (1.81e-1)" "unprognostic (3.09e-2)" "unprognostic (2.16e-2)" "unprognostic (6.04e-2)" "unprognostic (1.39e-1)" "unprognostic (1.05e-1)" "unprognostic (8.44e-3)" "unprognostic (2.56e-2)" "unprognostic (1.01e-1)" "unprognostic (1.62e-1)" "unprognostic (6.77e-2)" 10.8 4.7 30.0 1.9 48.9 0.3 3.2 39.2 32.6 4.4 3.7 1.8 0.7 4.6 1.2 2.5 2.2 4.4 3.4 28.3 29.4 2.0 1.0 2.4 2.5 42.5 36.6 9.9 1.9 0.6 0.7 6.2 49.5 1.7 1.9 4.3 3.3 1.6 1.5 2.3 1.3 3.3 40.2 1.9 1.5 3.0 33.7 0.8 1.9 5.8 1.5 2.7 2.4 70.9 0.2 0.0 19.8 0.4 15.5 8.7 0.7 0.2 1.3 0.0 1.1 0.3 0.4 0.4 0.5 1.8 0.4 0.6 0.0 0.0 0.0 0.8 0.1 0.1 1.0 0.0 2.2 0.3 0.3 10.7 0.4 0.1 0.0 0.1 2.3 0.6 0.0 0.2 0.4 0.9 0.1 0.1 0.8 0.8 0.6 0.1 0.5 0.2 0.0 0.2 0.5 0.2 0.0 0.0 3.0 3.4 0.1 0.0 6.4 1.7 0.3 0.1 0.3 0.5 1.1 0.2 1.6 0.0 9.6 0.2 0.0 0.0 0.2 0.0 0.4 0.1 0.2 0.1 0.0 0.1 0.2 0.4 0.4 0.0 0.0 0.1 0.1 0.0 30.0 48.9 39.2 32.6 28.3 29.4 42.5 36.6 49.5 40.2 33.7 70.9 14.8 0.0 0.6 152.8 0.2 2.4 0.2 0.1 0.0 1.3 1.3 1.4 2.2 2.8 0.1 0.0 0.0 0.2 0.5 0.1 0.0 1.0 125.0 0.9 9.7 13.0 0.0 0.0 1.2 0.0 0.1 16.3 0.0 0.4 0.0 8.6 19.6 0.3 0.4 3.3 1.5 0.0 0.0 0.6 3.3 351.7 15.8 0.7 16.0 32.8 0.0 23.5 0.0 198.5 320.6 0.1 0.0 22.2 1.6 0.3 0.0 0.1 0.2 1.5 6.6 16.2 8.3 4.5 2.8 0.5 2.3 0.0 0.6 3.3 0.0 0.1 RGPD3 RGP3 ENSG00000153165 "RANBP2 like and GRIP domain containing 3" A6NKT7 2 106391290-106468413 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 6.9" "Cell type enriched" "Detected in some" 4 "Early spermatids: 19.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HEL: 1.5;MOLT-4: 4.6;RPMI-8226: 1.4" "HPA049497, HPA051675, HPA067564" Uncertain Approved "Nuclear membrane,Vesicles" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nuclear membrane, Vesicles" "HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (2.91e-1)" "unprognostic (1.62e-1)" "unprognostic (5.51e-2)" "unprognostic (6.61e-2)" "unprognostic (2.53e-1)" "unprognostic (1.33e-1)" "unprognostic (1.26e-1)" "unprognostic (6.86e-2)" "unprognostic (3.10e-1)" "unprognostic (2.49e-2)" "unprognostic (3.70e-1)" "unprognostic (3.44e-1)" "unprognostic (4.74e-3)" "unprognostic (5.05e-2)" "unprognostic (3.70e-1)" "unprognostic (3.42e-1)" "unprognostic (1.34e-1)" 0.2 0.1 0.4 0.1 0.4 0.4 0.2 0.4 0.5 0.1 0.9 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.4 0.4 0.7 0.7 0.2 0.1 1.0 0.6 0.2 0.2 0.2 0.5 0.2 1.1 0.2 0.1 0.9 0.2 0.2 0.2 0.3 0.1 0.1 0.4 0.6 0.1 6.9 0.7 1.9 0.1 0.1 0.2 0.3 0.1 0.5 0.1 0.2 0.2 0.2 0.1 0.2 0.1 0.2 0.2 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.5 0.1 0.6 0.1 0.2 0.1 0.0 1.5 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.5 0.1 0.1 0.1 0.4 0.3 0.0 0.2 0.1 4.6 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.1 0.3 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.4 0.4 0.5 0.4 0.4 1.0 0.6 1.1 0.4 0.7 0.5 0.0 0.0 1.1 1.6 0.1 0.1 0.1 0.0 0.0 1.6 0.0 0.0 2.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.1 0.1 0.5 0.0 0.0 2.4 0.2 0.0 0.4 0.0 0.1 1.3 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.3 4.4 0.0 0.1 0.0 1.9 0.0 0.0 0.0 2.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.7 0.2 0.0 0.0 0.4 3.2 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 RHOH "ARHH, TTF" ENSG00000168421 "Ras homolog family member H" Q15669 4 40191053-40246967 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 62.9;lymphoid tissue: 98.2" "Cell type enhanced" "Detected in many" "B-cells: 273.0;dendritic cells: 90.5;granulocytes: 141.8;NK-cells: 64.9;Plasma cells: 183.1;T-cells: 223.6" "Cancer enhanced" "Detected in many" "breast cancer: 4.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 126.3;HMC-1: 92.5;JURKAT: 123.7;MOLT-4: 179.4;U-266/70: 65.5;U-266/84: 56.8;U-698: 116.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA030345, HPA061314" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus, Vesicles" "HPA030345: AB_10601607, HPA061314: " "unprognostic (4.00e-2)" "unprognostic (1.83e-4)" "unprognostic (1.24e-2)" "unprognostic (2.22e-5)" "unprognostic (1.35e-1)" "unprognostic (1.32e-3)" "unprognostic (1.16e-1)" "unprognostic (2.73e-2)" "unprognostic (2.30e-2)" "unprognostic (4.30e-2)" "unprognostic (9.07e-2)" "unprognostic (1.38e-1)" "unprognostic (3.31e-6)" "unprognostic (2.96e-1)" "unprognostic (3.91e-2)" "unprognostic (4.46e-2)" "unprognostic (2.44e-2)" 2.2 0.9 0.7 36.4 0.6 62.9 13.2 0.5 0.8 2.9 0.6 6.3 4.8 1.6 0.9 2.9 1.5 6.4 0.7 0.6 0.8 1.2 2.7 5.7 86.0 1.1 1.3 0.9 1.4 0.4 0.7 0.9 0.9 2.7 5.6 0.0 3.9 0.9 0.6 1.2 20.6 1.5 1.0 42.6 8.2 0.7 0.8 98.2 1.8 0.3 85.2 10.6 1.6 1.0 0.2 0.4 0.5 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 126.3 0.1 0.0 0.1 0.1 0.1 0.0 0.0 2.6 0.0 18.8 0.1 0.0 0.0 21.1 92.5 1.5 0.0 0.0 0.0 0.1 0.1 123.7 1.4 1.2 0.0 0.0 179.4 13.3 2.3 0.0 0.4 19.1 0.3 4.3 0.0 0.0 0.1 0.1 0.3 0.8 0.2 0.1 5.7 0.5 0.5 0.0 0.5 0.1 0.2 65.5 56.8 116.3 0.1 4.4 0.1 210.3 1.1 168.7 112.2 0.8 99.3 164.3 176.9 151.1 1.9 212.1 274.3 220.5 8.4 74.2 1.2 26.1 268.4 124.1 0.7 0.6 0.5 0.8 0.6 0.8 1.1 1.3 0.9 1.0 0.8 1.0 2.9 3.2 9.9 0.3 273.0 7.1 1.4 0.3 1.8 0.0 11.1 6.7 1.1 1.5 2.9 0.0 0.0 0.1 90.5 0.3 0.0 0.1 0.6 0.6 0.5 2.3 0.0 23.4 0.3 0.0 0.2 3.6 9.7 1.0 141.8 0.0 1.8 0.2 2.2 0.0 0.3 0.4 0.0 4.4 16.2 0.7 0.0 28.4 56.9 8.4 11.3 0.0 64.9 0.5 0.1 0.0 0.1 0.0 183.1 1.4 0.0 0.4 1.0 0.0 0.0 2.0 2.0 0.3 0.2 0.3 7.0 0.3 223.6 0.1 0.3 2.0 RHPN1 "KIAA1929, ODF5, RHPN" ENSG00000158106 "Rhophilin Rho GTPase binding protein 1" Q8TCX5 8 143368876-143384221 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 20.1;thyroid gland: 20.4" "Cell type enhanced" "Detected in many" "Astrocytes: 47.0;Collecting duct cells: 38.6;Cone photoreceptor cells: 31.3;Respiratory ciliated cells: 38.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 28.3;MOLT-4: 25.8;RPMI-8226: 19.0;T-47d: 44.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA024288, HPA024671" Approved Approved Nucleoplasm NA NA "Cluster 43: Testis - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "HPA024288: AB_1856274, HPA024671: AB_1856275" "unprognostic (2.04e-1)" "unprognostic (3.71e-1)" "unprognostic (1.54e-2)" "unprognostic (2.20e-1)" "unprognostic (5.82e-2)" "unprognostic (6.38e-2)" "unprognostic (2.07e-3)" "unprognostic (3.12e-1)" "unprognostic (3.57e-1)" "unprognostic (1.02e-1)" "unprognostic (8.27e-3)" "unprognostic (1.23e-1)" "unprognostic (1.16e-2)" "unprognostic (1.24e-3)" "unprognostic (9.92e-2)" "unprognostic (1.43e-1)" "unprognostic (1.77e-2)" 2.6 1.6 11.8 0.9 9.1 2.1 4.7 6.7 12.9 3.3 8.5 2.0 0.1 1.3 1.3 2.4 5.0 0.7 1.1 13.5 8.2 13.6 1.3 3.5 1.1 7.5 9.3 0.7 4.2 2.9 20.1 0.1 7.2 4.0 0.1 0.6 3.6 1.9 0.3 2.7 3.0 0.3 5.9 5.3 3.0 4.0 9.9 8.8 20.4 0.0 0.5 2.6 1.9 7.1 2.9 4.9 1.2 3.8 0.0 0.0 2.3 0.0 0.0 0.1 0.0 0.7 1.9 0.2 9.8 0.0 0.2 1.3 0.0 0.0 0.0 0.6 4.4 0.0 3.5 0.3 0.4 0.3 3.1 0.0 0.8 0.0 0.0 0.9 1.0 11.5 1.1 5.8 0.0 28.3 25.8 2.6 1.7 5.9 13.4 7.0 0.0 19.0 3.9 4.6 7.2 2.7 1.5 8.1 1.8 0.0 44.2 0.0 0.0 0.0 5.1 0.1 0.2 1.0 0.6 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 9.1 6.7 12.9 13.5 8.2 7.5 9.3 7.2 5.9 9.9 7.1 6.7 6.4 7.5 47.0 2.0 2.5 2.7 3.9 3.4 3.4 13.4 8.9 1.0 2.8 5.9 38.6 31.3 1.6 3.3 2.4 11.7 8.7 5.1 21.9 1.2 5.7 22.7 1.7 20.2 2.8 0.2 1.1 11.7 4.1 0.0 6.6 5.3 1.4 3.2 6.7 10.2 3.1 6.1 1.3 6.0 11.2 0.3 1.6 7.2 3.7 1.4 11.5 0.0 15.1 3.6 3.3 1.2 1.5 1.4 3.2 0.0 15.8 38.6 25.2 0.0 0.7 1.5 7.6 7.2 2.5 1.4 1.9 5.5 1.1 4.3 3.7 RILPL1 FLJ39378 ENSG00000188026 "Rab interacting lysosomal protein like 1" Q5EBL4 12 123470054-123533719 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 62.4;skeletal muscle: 88.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Oligodendrocytes: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041314 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" Nucleoplasm "HPA041314: AB_10795587" "unprognostic (2.21e-1)" "unprognostic (1.26e-1)" "unprognostic (3.71e-2)" "unprognostic (5.36e-2)" "unprognostic (3.12e-2)" "unprognostic (2.99e-3)" "unprognostic (1.94e-2)" "unprognostic (1.61e-1)" "unprognostic (2.65e-1)" "unprognostic (1.75e-1)" "unprognostic (2.30e-2)" "unprognostic (8.30e-2)" "unprognostic (4.25e-2)" "unprognostic (2.98e-1)" "unprognostic (2.32e-1)" "unprognostic (6.07e-3)" "unprognostic (2.81e-1)" 7.8 9.0 17.1 3.1 21.1 2.6 7.5 18.6 18.3 10.7 17.9 10.5 1.3 12.0 4.1 5.1 9.5 3.4 62.4 15.2 16.7 6.8 4.2 6.8 1.8 19.0 19.7 8.5 3.7 6.6 6.4 7.3 18.6 9.1 1.4 3.0 6.8 7.4 88.9 6.8 4.2 6.3 15.9 4.4 5.5 4.1 18.0 1.5 13.3 41.1 1.0 9.5 7.5 27.1 8.3 11.4 10.1 7.9 11.1 10.4 10.6 14.6 8.1 7.8 6.9 7.1 1.9 0.3 7.1 14.3 5.6 8.9 7.5 7.0 3.1 8.4 13.8 1.1 8.1 10.6 19.4 0.4 3.0 11.9 13.6 8.7 12.5 19.5 8.0 1.5 6.6 0.4 8.0 13.8 0.9 2.7 7.4 2.4 11.9 1.3 5.5 0.4 5.6 8.5 1.6 9.3 7.8 6.7 17.9 5.5 9.0 0.2 16.0 10.2 5.1 14.8 9.4 1.7 0.9 0.2 10.4 0.0 6.5 0.4 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.4 0.5 0.4 1.1 0.3 0.3 0.3 0.2 0.2 17.1 21.1 18.6 18.3 15.2 16.7 19.0 19.7 18.6 15.9 18.0 27.1 13.0 38.5 11.7 32.3 0.7 4.6 5.1 3.4 6.2 14.1 4.6 14.7 9.8 4.3 7.2 11.0 6.2 9.1 0.7 0.2 1.9 2.2 1.8 6.3 18.0 8.5 0.0 0.0 28.8 2.2 6.2 9.4 1.1 7.4 1.3 18.9 9.7 1.6 5.7 23.5 16.4 1.3 0.0 1.3 2.4 1.6 15.5 3.3 5.4 18.7 0.9 21.4 0.0 13.6 64.9 2.2 0.5 8.2 0.3 5.1 0.1 2.6 4.1 6.4 6.6 14.4 9.9 0.9 2.9 2.3 3.8 9.3 2.0 21.5 0.7 3.3 RIN1 ENSG00000174791 "Ras and Rab interactor 1" Q13671 11 66330241-66336840 "Predicted intracellular proteins, RAS pathway related proteins" Endocytosis "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 26.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 25.7;Basal squamous epithelial cells: 23.3;Squamous epithelial cells: 18.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 9.7" "Lineage enriched" "Detected in many" 6 "monocytes: 9.7" "Cell line enhanced" "Detected in many" "hTCEpi: 44.3;U-2197: 40.7" "Low region specificity" "Detected in many" HPA035491 Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear membrane" Nucleoplasm "HPA035491: AB_10601608" "unprognostic (1.25e-2)" "unprognostic (1.04e-1)" "unprognostic (4.69e-2)" "prognostic favorable (2.21e-4)" "unprognostic (1.11e-2)" "unprognostic (2.57e-1)" "unprognostic (6.82e-3)" "unprognostic (3.84e-2)" "unprognostic (1.11e-2)" "unprognostic (2.52e-3)" "unprognostic (8.32e-2)" "unprognostic (2.99e-1)" "prognostic unfavorable (9.34e-7)" "unprognostic (2.42e-2)" "unprognostic (1.14e-1)" "unprognostic (7.82e-3)" "unprognostic (2.46e-1)" 4.8 4.3 3.7 2.3 4.9 1.1 4.4 3.3 5.7 8.3 1.5 5.2 2.7 4.4 0.2 20.4 5.6 1.4 3.4 6.3 1.6 4.3 1.3 4.9 0.5 1.0 1.2 3.7 5.2 0.4 7.2 1.4 1.1 7.1 1.0 0.2 5.1 0.8 7.5 26.6 4.3 0.6 0.8 6.1 6.8 3.7 2.0 0.5 2.4 0.5 0.4 5.4 11.3 2.6 2.3 5.7 2.3 5.3 2.8 14.5 1.2 13.7 18.0 14.4 6.8 3.3 9.3 0.5 5.0 13.6 5.2 12.9 0.0 24.3 1.8 1.1 0.0 0.8 4.4 4.1 5.5 0.1 4.2 15.9 44.3 12.4 8.0 17.1 2.8 0.6 0.3 0.1 6.1 0.5 0.3 11.0 0.6 3.9 12.6 0.1 5.4 0.1 3.9 3.0 10.9 2.3 3.2 2.5 20.5 0.6 1.8 1.3 6.5 18.7 7.9 40.7 3.3 0.3 0.9 0.0 26.9 3.5 6.3 0.1 2.7 0.0 0.2 4.7 0.6 0.1 0.4 0.2 1.7 0.0 0.5 0.2 0.0 0.1 9.7 0.0 0.1 1.8 3.7 4.9 3.3 5.7 6.3 1.6 1.0 1.2 1.1 0.8 2.0 2.6 3.9 0.0 0.5 1.3 0.8 13.4 9.3 25.7 23.3 3.8 3.5 4.3 0.8 4.3 4.8 0.0 0.0 0.8 0.5 9.6 0.0 4.1 0.5 2.4 5.1 5.3 3.0 0.0 6.0 6.9 4.8 5.6 5.6 1.8 4.5 0.1 7.9 0.2 4.7 0.0 2.3 4.5 2.0 8.7 6.5 2.0 4.4 6.4 1.8 1.0 8.1 0.7 1.0 0.5 0.5 8.9 7.8 1.9 1.4 4.0 9.1 0.1 3.4 1.2 0.0 4.2 3.4 1.2 0.9 18.6 15.2 0.3 2.2 1.6 9.2 5.8 RIN2 RASSF4 ENSG00000132669 "Ras and Rab interactor 2" Q8WYP3 20 19757606-20002457 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Endocytosis "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 198.5;Microglial cells: 191.1;Oligodendrocyte precursor cells: 296.6;Oligodendrocytes: 202.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "PC-3: 47.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034641 Approved Approved "Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "Nucleoli, Golgi apparatus" "HPA034641: AB_10671230" "unprognostic (8.23e-3)" "unprognostic (8.09e-3)" "unprognostic (3.71e-2)" "unprognostic (1.97e-1)" "unprognostic (3.12e-2)" "unprognostic (3.86e-2)" "unprognostic (1.61e-2)" "unprognostic (3.69e-2)" "unprognostic (2.69e-2)" "unprognostic (1.78e-3)" "unprognostic (2.49e-1)" "unprognostic (6.27e-2)" "prognostic favorable (8.34e-6)" "unprognostic (3.10e-1)" "unprognostic (2.08e-2)" "unprognostic (8.02e-3)" "unprognostic (3.63e-2)" 14.2 6.4 8.7 8.6 13.5 6.1 9.5 9.4 7.1 14.4 14.4 12.5 13.3 14.1 3.9 13.6 11.7 17.8 18.7 9.5 10.8 12.1 5.3 18.3 4.7 14.6 13.2 15.0 6.5 4.6 1.4 19.8 12.8 9.4 12.7 5.5 15.6 13.5 9.4 8.2 14.7 16.2 9.5 16.8 8.8 1.8 12.7 3.0 13.7 13.2 5.3 8.1 3.8 14.0 6.7 22.4 4.1 13.7 23.3 14.2 13.1 5.9 22.8 5.7 3.0 10.0 5.8 0.0 24.0 14.6 10.6 24.7 0.1 33.5 6.3 2.7 0.1 0.0 3.5 0.8 5.4 0.0 0.1 21.7 6.1 10.7 11.9 13.4 30.6 0.0 0.1 0.4 17.0 5.3 0.1 0.4 0.7 3.2 47.1 0.1 13.8 3.4 7.2 9.2 3.5 0.9 5.3 23.7 0.1 4.1 2.0 1.4 33.7 11.4 2.9 8.1 9.2 0.1 0.1 0.0 8.0 0.0 2.0 0.2 1.6 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 1.0 0.1 0.0 0.4 8.7 13.5 9.4 7.1 9.5 10.8 14.6 13.2 12.8 9.5 12.7 14.0 52.3 64.1 17.5 198.5 1.4 41.9 18.5 30.9 24.5 6.1 25.6 18.4 34.3 14.3 23.7 31.3 8.4 6.8 0.2 30.4 43.0 17.5 1.0 50.0 47.3 52.7 14.4 0.4 5.9 34.5 7.4 33.2 10.7 87.3 0.0 32.4 105.3 4.2 100.2 6.7 82.8 17.2 26.4 60.3 40.3 0.8 19.3 37.7 21.4 191.1 21.4 33.2 1.0 296.6 202.4 26.2 10.5 15.4 0.8 22.3 23.0 50.1 27.1 1.9 0.0 25.4 22.6 0.5 0.8 33.6 54.0 7.1 2.9 43.1 21.9 32.2 RNASE13 RAL1 ENSG00000206150 "Ribonuclease A family member 13 (inactive)" Q5GAN3 14 21032818-21034807 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "epididymis: 306.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (2.54e-1)" "unprognostic (2.52e-1)" "unprognostic (2.86e-1)" "unprognostic (8.40e-2)" "unprognostic (1.93e-1)" "unprognostic (7.15e-2)" "unprognostic (1.63e-3)" "unprognostic (5.20e-4)" "unprognostic (1.47e-2)" 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.1 306.9 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.9 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.0 0.1 0.3 0.3 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RNASE6 "RAD1, RNaseK6, RNS6" ENSG00000169413 "Ribonuclease A family member k6" Q93091 14 20781268-20782467 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 110.5" "Cell type enhanced" "Detected in many" "B-cells: 108.0;dendritic cells: 221.7;Hofbauer cells: 207.9;Kupffer cells: 551.2;Langerhans cells: 198.4;Macrophages: 270.3;monocytes: 115.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 1238.8" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 7 "RPMI-8226: 65.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA000698 Approved "Secreted to blood" NA NA 2600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA000698: AB_2181340" "unprognostic (5.04e-2)" "unprognostic (5.21e-3)" "unprognostic (3.59e-2)" "unprognostic (4.05e-2)" "unprognostic (1.74e-1)" "unprognostic (7.31e-2)" "unprognostic (7.91e-2)" "unprognostic (2.29e-1)" "unprognostic (4.45e-1)" "unprognostic (1.65e-1)" "unprognostic (2.04e-1)" "unprognostic (2.73e-1)" "unprognostic (2.85e-3)" "unprognostic (9.62e-2)" "unprognostic (5.60e-3)" "unprognostic (3.46e-2)" "unprognostic (5.54e-2)" 25.2 29.5 8.0 59.6 7.5 27.5 24.0 7.8 13.6 31.6 10.0 27.7 17.3 10.6 78.4 16.0 11.3 47.7 11.7 7.3 10.9 12.2 21.1 29.6 110.5 13.6 10.1 9.9 8.4 9.0 4.3 44.8 11.9 7.9 34.0 1.8 11.2 17.2 2.0 8.6 33.4 23.6 10.8 62.1 14.9 4.5 12.6 43.8 5.5 6.0 84.5 43.3 5.1 19.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 2.1 2.1 0.0 0.0 0.0 0.0 0.0 1.7 4.7 0.6 0.2 0.0 0.0 1.9 4.6 0.0 0.0 0.0 0.2 0.0 65.6 1.1 0.7 0.0 0.1 0.0 0.0 0.1 0.1 0.0 8.1 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.7 0.0 441.1 537.3 12.8 5.3 124.8 12.0 324.7 13.6 5.6 513.3 410.3 6.4 1.0 199.0 36.7 2.0 1238.8 1.1 329.8 8.0 7.5 7.8 13.6 7.3 10.9 13.6 10.1 11.9 10.8 12.6 19.5 1.6 6.4 7.5 0.0 108.0 4.5 0.2 0.0 1.8 0.0 1.4 2.8 0.6 14.3 1.2 0.0 0.0 1.1 221.7 2.6 0.0 0.0 0.8 0.1 0.0 3.8 0.0 12.0 0.0 0.0 1.6 1.4 1.1 0.2 0.0 0.0 8.6 3.3 207.9 0.0 0.0 0.5 2.0 551.2 198.4 4.8 2.8 270.3 21.4 1.9 115.8 0.0 9.2 0.0 0.0 0.0 12.6 0.7 52.4 0.2 0.4 0.5 0.2 0.4 13.1 0.6 0.6 0.1 0.7 0.6 3.8 2.2 7.8 0.0 3.4 1.2 RNF130 "G1RZFP, GOLIATH, GP" ENSG00000113269 "Ring finger protein 130" Q86XS8 5 179911651-180072113 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 295.7;Kupffer cells: 393.7;Macrophages: 283.0;monocytes: 276.4;Oligodendrocytes: 514.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 261.6;classical monocyte: 513.2;eosinophil: 331.3;intermediate monocyte: 355.0;myeloid DC: 407.4;neutrophil: 890.5;non-classical monocyte: 328.7;plasmacytoid DC: 317.2" "Group enriched" "Detected in all" 11 "dendritic cells: 407.4;granulocytes: 890.5;monocytes: 513.2" "Cell line enhanced" "Detected in many" "HMC-1: 179.3" "Low region specificity" "Detected in all" HPA014499 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "HPA014499: AB_1856328" "unprognostic (2.01e-1)" "prognostic favorable (6.32e-4)" "unprognostic (2.43e-1)" "unprognostic (1.37e-1)" "unprognostic (2.24e-1)" "unprognostic (1.62e-2)" "unprognostic (2.83e-1)" "unprognostic (2.02e-3)" "unprognostic (2.93e-2)" "unprognostic (1.78e-1)" "unprognostic (4.00e-2)" "unprognostic (2.81e-1)" "unprognostic (1.14e-1)" "unprognostic (8.41e-2)" "unprognostic (4.17e-2)" "unprognostic (4.32e-1)" "unprognostic (1.38e-2)" 94.2 43.4 79.7 47.7 103.2 94.0 50.2 102.3 114.1 55.5 75.5 40.1 28.1 42.1 35.6 26.4 46.8 55.9 36.2 81.4 85.8 49.4 167.1 62.6 39.2 112.8 94.6 52.2 64.2 28.0 16.6 48.4 110.6 35.1 41.9 14.3 84.6 60.2 33.2 14.6 32.6 52.6 98.4 51.8 34.7 17.5 92.3 17.7 32.3 53.7 25.8 51.6 19.3 138.2 32.7 26.8 125.5 110.9 117.4 54.5 21.9 20.9 29.1 24.1 25.3 8.4 31.8 0.1 69.6 47.5 47.7 3.0 81.5 49.7 26.0 0.3 54.6 57.7 11.8 25.4 27.3 14.9 179.3 52.2 25.9 2.3 15.3 65.6 42.3 57.3 9.7 0.4 27.0 71.0 28.7 68.8 32.7 6.7 33.8 65.9 27.9 0.1 38.7 7.4 68.4 28.8 43.2 34.4 126.5 45.7 40.8 38.6 36.6 50.6 18.9 38.8 27.1 0.4 24.1 6.2 7.7 132.0 41.2 261.6 513.2 331.3 25.4 355.0 21.7 15.8 10.9 12.3 407.4 15.8 12.4 13.6 890.5 53.6 328.7 317.2 1.6 323.8 79.7 103.2 102.3 114.1 81.4 85.8 112.8 94.6 110.6 98.4 92.3 138.2 75.0 19.2 21.4 119.1 22.4 14.1 22.6 27.0 12.5 26.9 55.0 45.5 35.1 81.5 34.7 42.3 52.1 11.2 123.7 26.9 23.5 56.8 11.8 49.0 38.8 48.3 16.3 69.2 119.0 76.5 16.6 57.9 25.5 38.3 82.9 28.9 47.5 147.0 295.7 6.7 144.0 36.1 36.7 393.7 170.7 24.2 36.7 283.0 32.0 141.5 276.4 21.8 28.8 242.8 514.2 41.6 32.1 48.2 11.7 27.2 32.6 52.0 56.3 20.3 46.0 32.4 48.5 13.2 32.9 10.9 12.9 8.8 26.2 33.7 52.9 23.3 RNF145 FLJ31951 ENSG00000145860 "Ring finger protein 145" Q96MT1 5 159157409-159210053 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "B-cells: 11.4;granulocytes: 16.0;T-cells: 6.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036562 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Plasma membrane, Cytosol" "HPA036562: AB_10696657" "unprognostic (1.57e-1)" "unprognostic (9.02e-3)" "unprognostic (4.11e-2)" "unprognostic (3.88e-2)" "unprognostic (3.24e-2)" "unprognostic (2.93e-2)" "prognostic unfavorable (1.64e-6)" "unprognostic (1.35e-1)" "unprognostic (1.02e-2)" "unprognostic (1.54e-1)" "unprognostic (3.53e-1)" "unprognostic (1.67e-1)" "unprognostic (8.92e-3)" "unprognostic (1.49e-1)" "unprognostic (1.00e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-1)" 27.4 39.3 13.7 39.4 15.9 20.4 28.2 16.2 16.1 24.7 18.6 26.4 12.2 21.0 30.9 53.1 16.9 48.3 18.8 15.6 19.8 19.5 15.3 73.6 38.7 11.1 13.1 29.0 12.3 47.7 19.4 52.4 11.6 25.9 29.3 33.8 25.6 32.7 9.0 22.3 16.6 27.4 14.3 29.2 26.7 12.1 20.3 26.5 33.8 13.7 48.4 68.1 24.4 14.7 65.5 63.5 95.2 115.1 98.5 43.6 18.6 51.3 88.9 46.3 74.6 22.2 52.9 22.4 89.7 45.3 87.9 83.1 75.9 67.3 80.9 92.7 27.2 47.2 68.5 18.4 42.1 31.4 43.2 27.0 118.8 43.2 63.0 64.7 46.2 53.6 47.7 83.6 44.1 1.9 36.1 9.8 41.3 20.5 32.0 47.3 41.6 44.8 61.4 22.3 34.5 63.9 51.8 54.7 86.5 64.7 38.5 28.4 49.7 51.6 47.0 41.9 92.1 18.4 27.6 20.6 60.3 38.4 113.1 3.5 2.5 16.0 3.0 2.6 3.5 11.4 4.4 3.6 1.9 5.1 5.8 4.0 9.5 2.3 2.3 2.7 6.3 1.3 13.7 15.9 16.2 16.1 15.6 19.8 11.1 13.1 11.6 14.3 20.3 14.7 34.1 112.2 244.1 25.1 62.9 122.7 102.0 90.0 73.4 106.7 97.2 77.3 12.7 65.8 114.0 36.8 58.4 2.8 55.1 98.4 19.6 75.0 28.9 27.5 37.1 75.7 54.1 67.5 89.2 114.4 24.3 45.7 52.0 36.7 69.1 30.2 127.8 19.5 45.5 114.4 74.2 41.8 32.6 115.0 240.8 39.5 46.3 69.4 65.8 52.5 153.9 56.1 47.4 40.2 38.9 108.6 53.7 51.9 38.1 123.8 16.9 10.6 65.6 53.4 46.0 25.4 46.5 19.2 34.8 81.9 99.4 10.9 69.3 19.0 72.0 163.1 RNF170 "ADSA, DKFZP564A022, SNAX1" ENSG00000120925 "Ring finger protein 170" Q96K19 8 42849637-42897290 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 89.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050931, HPA054621" Uncertain NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" "HPA050931: AB_2681279, HPA054621: AB_2682545" "unprognostic (3.06e-2)" "unprognostic (4.20e-1)" "unprognostic (9.54e-2)" "unprognostic (6.37e-2)" "unprognostic (4.59e-2)" "unprognostic (2.84e-2)" "unprognostic (1.04e-1)" "unprognostic (1.32e-1)" "unprognostic (3.23e-2)" "unprognostic (1.17e-1)" "unprognostic (2.59e-1)" "unprognostic (3.03e-2)" "unprognostic (1.61e-3)" "unprognostic (4.13e-3)" "unprognostic (2.00e-1)" "unprognostic (1.49e-1)" "unprognostic (2.13e-1)" 9.3 11.7 14.5 7.5 15.6 2.4 12.7 16.3 16.8 7.9 11.5 11.1 10.3 9.5 14.9 14.2 9.3 9.2 7.7 14.1 15.8 16.4 19.7 9.3 9.4 15.9 15.5 12.3 8.1 13.5 9.5 19.2 16.2 11.0 11.3 35.6 11.0 10.6 11.9 15.1 11.4 7.6 15.0 9.1 10.7 5.9 15.6 6.1 28.8 9.2 9.9 7.6 8.5 18.3 11.4 18.1 18.2 9.2 29.4 29.7 10.8 13.3 18.1 12.3 13.2 8.5 36.0 13.6 15.7 12.8 22.1 9.6 9.6 13.2 10.8 9.4 10.4 15.9 8.5 9.3 16.1 2.0 10.9 26.0 20.4 9.3 18.8 16.0 13.3 15.0 14.6 15.8 19.9 3.4 17.0 9.5 8.6 24.1 6.5 8.7 24.2 7.7 19.6 10.8 4.7 14.3 12.8 8.9 23.0 17.7 23.1 9.5 19.5 13.2 5.8 17.8 4.3 25.2 26.4 15.7 18.2 6.7 13.6 1.4 5.7 2.1 2.9 5.7 4.2 6.6 4.8 5.3 8.8 3.9 5.6 4.1 0.6 4.9 5.5 8.9 6.7 4.5 14.5 15.6 16.3 16.8 14.1 15.8 15.9 15.5 16.2 15.0 15.6 18.3 13.5 48.1 20.5 41.1 16.1 7.6 13.1 22.3 5.7 44.8 14.9 9.5 11.5 15.7 29.2 23.9 89.6 41.6 9.8 22.1 17.6 21.6 1.7 16.0 14.5 15.2 13.1 5.5 36.7 27.8 19.4 20.0 11.2 13.3 9.5 25.5 21.8 21.7 22.9 21.9 43.7 15.3 20.3 18.5 9.2 2.4 15.2 15.4 8.8 15.9 21.9 31.8 30.9 36.2 75.9 32.2 18.4 20.7 10.7 9.6 34.5 22.1 33.3 72.1 13.1 23.9 12.1 14.9 19.3 12.5 11.5 31.2 12.8 25.7 16.6 12.2 RNF175 FLJ34190 ENSG00000145428 "Ring finger protein 175" Q8N4F7 4 153710160-153760024 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.6;choroid plexus: 10.8" "Group enriched" "Detected in some" 5 "Early spermatids: 72.8;Excitatory neurons: 91.4;Inhibitory neurons: 95.7;Oligodendrocyte precursor cells: 38.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 8.8;HSkMC: 5.8;REH: 6.7;SH-SY5Y: 7.6;THP-1: 17.5;U-87 MG: 4.5" HPA035837 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 65: Brain - Ion transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA035837: AB_10601609" "unprognostic (3.23e-2)" "unprognostic (4.12e-2)" "unprognostic (3.34e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (3.11e-4)" "unprognostic (9.00e-2)" "unprognostic (2.65e-1)" "unprognostic (7.15e-4)" "unprognostic (1.17e-1)" "unprognostic (2.96e-3)" "unprognostic (6.30e-3)" "unprognostic (1.42e-1)" "unprognostic (3.63e-4)" "unprognostic (7.25e-3)" "unprognostic (3.27e-1)" "unprognostic (1.28e-1)" "unprognostic (7.66e-2)" 1.5 2.5 18.8 2.9 19.2 6.1 0.8 15.0 27.6 3.0 10.8 0.6 0.1 0.2 0.9 0.6 0.5 1.0 4.0 18.3 21.8 0.2 0.4 1.4 1.2 17.7 15.3 0.1 0.3 0.0 4.0 0.1 17.6 2.4 0.1 3.5 1.4 3.4 0.1 0.7 0.5 0.1 14.1 2.5 0.3 1.6 18.0 0.1 0.2 0.5 0.6 0.5 1.5 17.5 0.2 0.0 8.8 0.0 0.0 0.6 0.0 0.0 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 5.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 3.0 0.0 0.0 6.7 0.0 0.3 0.0 0.1 0.0 7.6 0.0 0.0 0.2 0.1 0.0 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.9 0.0 0.0 1.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.9 0.0 2.2 0.0 2.4 0.0 2.1 0.0 0.6 0.6 18.8 19.2 15.0 27.6 18.3 21.8 17.7 15.3 17.6 14.1 18.0 17.5 0.1 0.0 0.5 6.8 0.0 0.4 0.1 0.6 0.6 0.7 0.1 0.6 4.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 72.8 0.0 0.1 0.2 0.0 0.4 91.4 0.0 0.0 2.9 0.0 0.2 0.0 0.4 0.0 0.0 0.5 0.0 95.7 0.0 0.0 5.9 2.9 14.6 0.0 1.5 1.8 2.8 0.7 0.8 0.0 38.7 2.8 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.7 1.6 0.0 0.0 0.3 1.5 1.3 0.0 0.3 0.0 0.6 0.0 0.0 0.2 RNF5 "G16, NG2, RING5, RMA1" ENSG00000204308 "Ring finger protein 5" Q99942 6 32178405-32180793 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 371.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034107, HPA065032" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Endoplasmic reticulum" "CAB034107: AB_2238618, HPA065032: AB_2685408" "unprognostic (1.94e-1)" "unprognostic (1.31e-1)" "unprognostic (1.49e-1)" "unprognostic (4.45e-3)" "unprognostic (1.35e-2)" "unprognostic (1.23e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-2)" "unprognostic (4.07e-1)" "prognostic favorable (2.44e-4)" "unprognostic (1.95e-1)" "unprognostic (8.93e-3)" "unprognostic (2.91e-3)" "unprognostic (8.84e-2)" "unprognostic (9.17e-2)" "unprognostic (2.72e-1)" "unprognostic (2.99e-2)" 38.2 75.9 60.4 29.2 63.4 40.4 44.5 64.6 66.0 44.9 59.4 59.5 61.6 44.8 45.8 37.5 54.1 46.1 81.7 59.2 60.6 115.6 126.2 38.7 43.1 65.0 60.6 60.4 41.6 55.5 17.2 30.1 62.6 44.0 62.4 42.9 43.9 31.7 89.6 44.6 76.5 30.5 62.8 38.8 55.3 29.5 61.8 60.7 48.6 76.5 43.4 45.1 38.8 67.0 51.2 66.1 43.7 167.5 46.9 31.3 34.0 20.6 26.5 44.4 48.7 89.1 42.1 65.2 70.8 47.9 62.5 41.7 80.3 45.1 45.2 41.8 107.5 53.9 69.5 184.4 55.0 0.2 101.2 32.3 60.3 73.3 53.6 77.2 89.1 115.0 136.6 67.8 63.8 71.9 66.5 151.5 0.3 71.8 28.7 44.4 48.2 88.2 124.0 32.6 44.8 92.1 39.9 42.4 46.7 39.9 87.0 183.0 40.3 48.1 44.7 0.5 79.1 38.6 63.5 79.3 33.2 116.4 29.6 64.8 45.7 75.8 64.8 65.9 55.6 64.6 52.5 57.6 64.7 56.2 57.5 58.3 22.1 79.6 46.7 264.6 58.2 75.0 60.4 63.4 64.6 66.0 59.2 60.6 65.0 60.6 62.6 62.8 61.8 67.0 38.3 19.2 41.1 2.9 52.7 95.7 70.0 146.6 52.3 23.6 61.8 56.5 62.9 87.2 79.5 92.0 0.0 78.1 70.3 151.9 283.7 110.8 21.6 47.2 31.7 50.9 73.2 126.3 3.4 91.3 101.7 44.6 28.5 31.7 56.3 41.5 47.8 131.5 68.9 33.7 3.5 83.0 132.2 51.1 171.7 22.6 59.4 43.3 85.4 1.0 69.5 91.3 65.9 1.5 10.0 78.5 173.0 72.6 45.5 58.4 270.6 371.6 73.4 27.6 65.7 50.6 63.0 55.7 37.7 44.4 84.4 84.1 53.8 42.8 100.3 56.5 RNLS "C10orf59, FLJ11218, renalase" ENSG00000184719 "Renalase, FAD dependent amine oxidase" Q5VYX0 10 88273864-88584530 "Enzymes, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 103.0;Inhibitory neurons: 101.1;Oligodendrocyte precursor cells: 51.8;Oligodendrocytes: 61.8;Proximal tubular cells: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 18.3;fHDF/TERT166: 17.1;HSkMC: 19.5" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 10500000000 "Cluster 7: Monocytes - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.27e-2)" "unprognostic (9.16e-2)" "unprognostic (1.27e-1)" "unprognostic (2.58e-1)" "unprognostic (1.46e-3)" "unprognostic (1.99e-1)" "unprognostic (2.01e-1)" "unprognostic (2.29e-1)" "unprognostic (1.32e-1)" "unprognostic (1.59e-1)" "unprognostic (3.98e-1)" "unprognostic (1.14e-1)" "unprognostic (1.75e-2)" "unprognostic (7.74e-3)" "unprognostic (1.37e-2)" "unprognostic (9.80e-2)" "unprognostic (1.71e-1)" 7.1 13.4 2.0 2.8 2.4 2.2 6.7 6.1 3.5 7.4 7.2 7.6 5.5 5.0 5.3 4.9 6.1 5.5 11.8 2.0 2.9 16.6 8.7 3.0 3.8 5.0 6.6 5.8 8.2 9.0 5.3 2.0 5.2 7.0 8.3 4.8 6.0 3.9 11.8 4.3 5.6 3.5 3.4 2.8 6.7 5.3 2.7 2.5 9.1 9.8 4.0 4.7 4.4 3.2 18.3 8.2 0.3 0.1 2.4 2.8 0.0 5.1 0.5 2.7 2.3 1.0 5.2 0.0 8.0 17.1 0.0 2.4 0.0 0.9 2.2 3.8 0.1 2.9 5.1 0.2 11.2 0.0 0.5 19.5 1.4 10.2 0.1 0.3 5.7 0.1 1.4 9.2 0.1 6.3 0.0 3.5 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.1 4.3 0.1 0.1 4.0 12.4 4.9 2.2 8.9 1.3 2.5 4.1 6.3 3.9 5.3 8.4 0.2 0.0 9.8 0.0 0.0 2.1 1.2 2.3 3.6 1.7 2.4 1.7 1.6 3.1 2.2 1.8 1.4 0.1 2.7 2.3 2.7 0.9 1.8 2.0 2.4 6.1 3.5 2.0 2.9 5.0 6.6 5.2 3.4 2.7 3.2 1.2 3.2 1.5 32.0 5.5 3.2 6.8 5.7 4.0 6.5 5.5 3.9 16.7 4.3 5.8 1.8 2.1 2.0 3.2 6.2 23.5 6.4 8.9 3.8 3.1 1.3 5.4 4.6 103.0 9.6 0.5 6.2 7.1 3.2 1.3 2.2 2.5 10.1 6.5 5.0 101.1 5.5 2.0 4.7 3.8 4.3 1.5 3.8 3.6 40.3 3.7 6.8 3.1 51.8 61.8 4.2 8.9 6.4 3.9 4.4 8.5 43.1 1.6 5.7 0.0 4.6 4.6 4.7 8.2 10.4 5.5 1.6 3.0 2.9 7.2 6.9 ROBO4 "ECSM4, FLJ20798, MRB" ENSG00000154133 "Roundabout guidance receptor 4" Q8WZ75 11 124883691-124898500 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Adipocytes: 181.5;Endothelial cells: 119.7;Hepatic stellate cells: 148.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 247.6;TIME: 224.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065212 Approved "Plasma membrane" NA NA 380000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA065212: AB_2685434" "unprognostic (2.86e-1)" "unprognostic (9.35e-2)" "unprognostic (2.67e-1)" "unprognostic (1.07e-1)" "unprognostic (3.82e-2)" "unprognostic (6.97e-2)" "prognostic favorable (4.85e-4)" "unprognostic (7.94e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (1.73e-3)" "unprognostic (2.17e-1)" "unprognostic (1.17e-2)" "prognostic unfavorable (8.73e-4)" "unprognostic (1.55e-1)" "unprognostic (4.63e-1)" "unprognostic (5.15e-2)" 41.4 7.2 11.4 6.6 9.6 0.2 31.8 9.0 9.4 10.0 5.8 6.5 2.9 10.9 2.1 5.5 10.3 9.7 25.8 7.9 9.2 18.5 5.3 34.8 7.8 11.3 10.7 4.1 4.3 4.7 4.6 28.6 11.2 7.0 1.7 0.2 4.1 4.6 13.9 6.9 7.3 9.9 9.5 43.5 6.3 1.4 13.2 1.8 16.7 11.9 2.0 9.4 7.0 8.6 0.4 0.0 0.4 0.0 0.0 1.1 0.1 0.2 3.1 0.7 1.5 0.0 0.0 0.0 23.6 0.1 1.0 0.0 0.0 0.4 1.2 0.0 0.0 0.9 0.0 0.1 0.6 0.0 0.0 0.1 0.0 8.9 3.0 0.4 247.6 0.0 0.0 0.0 8.6 0.0 0.0 0.2 0.0 0.0 3.4 0.0 8.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 224.8 1.2 0.6 0.3 1.1 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 9.6 9.0 9.4 7.9 9.2 11.3 10.7 11.2 9.5 13.2 8.6 181.5 0.0 4.2 2.3 1.6 2.2 1.0 0.2 0.6 0.2 0.6 1.0 3.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.5 0.5 0.2 0.3 119.7 0.0 4.0 0.0 0.2 0.0 5.2 0.0 0.3 2.5 0.6 148.9 1.5 0.1 0.0 0.0 0.0 0.0 8.1 3.7 1.7 4.4 2.8 1.8 20.6 0.1 1.1 0.0 0.5 0.1 0.1 0.0 1.2 2.6 0.3 0.0 0.0 0.0 5.2 0.0 4.5 2.1 0.0 0.1 0.6 1.3 0.0 0.9 2.0 0.1 0.2 RORC "NR1F3, RORG, RZRG, TOR" ENSG00000143365 "RAR related orphan receptor C" P51449 1 151806071-151831845 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 86.2;skeletal muscle: 128.0" "Cell type enhanced" "Detected in many" "Distal tubular cells: 35.2;Hepatocytes: 47.8;Proximal enterocytes: 32.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 4.1" "Immune cell enriched" "Detected in many" 6 "MAIT T-cell: 50.3" "Lineage enriched" "Detected in many" 44 "T-cells: 50.3" "Cell line enhanced" "Detected in some" "HDLM-2: 23.8;Karpas-707: 11.5;MOLT-4: 6.3;RPMI-8226: 6.0;SK-BR-3: 5.7;T-47d: 9.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA065620 Supported "Nuclear bodies" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 44: HDLM-2 - Immune response" "Cluster 30: Mammary glandular cells - Lactation" "Nuclear bodies" "HPA065620: AB_2685521" "unprognostic (6.51e-2)" "unprognostic (7.78e-2)" "prognostic favorable (1.83e-4)" "unprognostic (9.20e-2)" "unprognostic (3.05e-4)" "unprognostic (6.29e-5)" "unprognostic (1.13e-3)" "unprognostic (8.94e-2)" "unprognostic (1.67e-1)" "unprognostic (7.88e-2)" "unprognostic (3.78e-2)" "unprognostic (2.42e-1)" "prognostic favorable (2.94e-5)" "unprognostic (2.13e-1)" "unprognostic (3.22e-1)" "unprognostic (1.82e-2)" "unprognostic (1.80e-2)" 2.9 4.9 0.2 1.8 0.1 0.4 7.5 4.1 0.3 6.5 5.2 9.3 11.6 1.9 4.6 5.4 21.2 3.7 11.6 0.2 0.4 18.8 86.2 12.7 0.9 0.9 1.6 0.3 59.2 33.5 18.3 0.0 0.7 15.8 9.2 0.0 41.0 11.0 128.0 24.7 13.9 0.3 0.8 1.3 19.8 10.7 0.4 52.7 26.4 58.8 2.4 3.0 3.4 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.1 0.0 0.0 0.0 23.8 0.0 0.0 2.5 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 11.5 0.0 0.3 6.3 0.0 0.0 0.0 0.0 0.0 0.1 6.0 0.1 0.0 0.0 0.2 0.1 5.7 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 50.3 0.0 8.0 7.5 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.4 5.8 1.2 0.2 0.1 4.1 0.3 0.2 0.4 0.9 1.6 0.7 0.8 0.4 0.4 0.1 6.4 6.0 0.3 0.8 2.0 4.4 3.1 3.4 0.0 18.4 9.8 5.9 21.5 5.3 16.5 0.0 0.0 1.8 12.0 35.2 8.3 0.4 15.3 2.6 0.7 9.6 5.3 0.1 7.0 0.0 0.3 17.3 18.9 0.0 0.3 1.8 47.8 0.1 0.0 0.0 20.0 16.2 2.7 0.3 0.9 0.6 0.6 3.6 0.0 0.2 0.0 0.0 0.0 0.0 3.2 16.0 0.4 0.3 5.0 32.9 17.1 10.5 0.0 0.0 4.2 0.5 0.2 0.0 5.0 3.0 0.0 6.8 0.1 15.3 3.5 RTL8B "CXX1c, FAM127C, MAR8B, SIRH4" ENSG00000212747 "Retrotransposon Gag like 8B" Q17RB0 X 135020513-135022542 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 103.8;Distal tubular cells: 29.4;Extravillous trophoblasts: 31.2;Syncytiotrophoblasts: 30.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "EFO-21: 52.9;U-2197: 67.7" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" "prognostic unfavorable (2.41e-5)" "unprognostic (1.13e-2)" "unprognostic (8.78e-3)" "unprognostic (1.08e-3)" "unprognostic (1.76e-1)" "unprognostic (2.86e-2)" "unprognostic (3.32e-3)" "unprognostic (4.34e-1)" "unprognostic (5.25e-2)" "unprognostic (1.62e-3)" "unprognostic (1.50e-2)" "unprognostic (2.33e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.72e-4)" "unprognostic (2.56e-1)" "unprognostic (2.02e-1)" "unprognostic (1.80e-2)" 15.9 22.2 6.7 4.3 7.7 0.2 14.4 7.2 7.9 18.4 4.1 18.3 2.4 21.4 6.3 19.8 15.6 6.8 19.2 6.0 7.8 12.4 2.5 12.4 2.1 7.8 7.1 14.6 6.6 8.2 13.4 9.2 7.4 15.3 3.2 15.0 13.7 12.3 8.6 14.4 7.5 12.1 7.3 7.6 11.7 5.2 7.3 1.5 10.7 7.5 2.9 18.7 17.2 7.3 0.0 6.0 19.6 16.0 14.4 9.3 0.1 21.8 30.1 17.2 18.3 10.7 0.8 0.0 52.9 32.0 5.3 0.9 3.8 2.8 12.8 0.1 10.7 2.7 19.1 0.0 23.6 0.0 0.0 40.7 2.4 13.1 0.0 0.6 12.5 0.0 0.0 0.0 29.4 26.2 0.0 1.6 5.6 0.0 25.1 0.0 22.4 0.1 20.1 4.9 13.3 31.9 16.9 10.6 9.0 5.2 8.9 11.6 16.9 0.1 9.3 67.7 0.6 0.0 0.0 0.1 26.0 0.0 10.9 0.0 1.6 0.0 0.0 1.0 0.0 0.0 0.1 0.2 0.9 0.0 0.5 0.3 0.2 0.0 1.6 0.6 0.0 0.8 6.7 7.7 7.2 7.9 6.0 7.8 7.8 7.1 7.4 7.3 7.3 7.3 14.4 12.8 7.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 13.5 14.0 0.0 0.0 3.7 11.0 0.0 103.8 0.4 0.0 29.4 12.6 0.0 8.2 16.1 9.7 0.0 0.0 0.0 9.6 31.2 6.9 0.0 14.3 0.0 4.8 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 3.1 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 17.0 0.7 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 30.9 0.4 8.9 0.0 0.0 RTP3 "LTM1, TMEM7, Z3CXXC3" ENSG00000163825 "Receptor transporter protein 3" Q9BQQ7 3 46497976-46500950 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 130 "liver: 119.5" "Cell type enriched" "Detected in some" 40 "Hepatocytes: 89.6" "Cancer enriched" "Detected in some" 5 "liver cancer: 22.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "SiHa: 12.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA075932 Uncertain Mitochondria NA NA "Cluster 62: Liver - Hemostasis" "Cluster 20: HeLa - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA075932: " "unprognostic (2.09e-1)" "unprognostic (1.64e-1)" "prognostic favorable (3.11e-6)" "unprognostic (1.08e-1)" "unprognostic (1.58e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.6 119.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 12.5 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.2 89.6 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.4 1.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 RUNX1T1 "AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2" ENSG00000079102 "RUNX1 partner transcriptional co-repressor 1" Q06455 8 91954967-92103286 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 93.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 142.1;Excitatory neurons: 196.9;Hepatic stellate cells: 124.2;Inhibitory neurons: 326.3;Oligodendrocyte precursor cells: 262.4" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in all" 7 "cerebellum: 93.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 19.6;fHDF/TERT166: 16.5;HEL: 35.9;HSkMC: 13.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049852, HPA070951" Approved Supported Nucleoplasm NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA049852: AB_2680914, HPA070951: AB_2686326" "unprognostic (2.37e-1)" "unprognostic (1.90e-1)" "unprognostic (1.90e-1)" "unprognostic (2.35e-1)" "unprognostic (1.62e-1)" "unprognostic (3.37e-4)" "unprognostic (2.29e-4)" "unprognostic (5.56e-3)" "unprognostic (1.24e-2)" "unprognostic (1.62e-2)" "unprognostic (2.11e-2)" "unprognostic (2.37e-1)" "unprognostic (5.70e-4)" "unprognostic (8.98e-3)" "unprognostic (6.78e-2)" "unprognostic (1.51e-1)" "unprognostic (7.80e-3)" 7.0 2.8 9.4 2.1 13.2 0.2 5.1 93.1 8.7 8.4 0.0 6.5 1.2 7.4 3.6 2.5 4.7 5.0 8.2 13.1 2.3 1.4 0.6 3.8 1.3 1.4 12.8 4.7 1.0 1.0 3.0 5.8 4.6 2.5 2.4 5.2 3.1 2.4 3.9 2.4 2.5 6.5 4.2 1.9 2.7 3.6 3.6 0.5 3.7 4.8 1.1 3.8 3.9 1.2 0.0 0.0 0.4 1.9 5.0 7.2 0.0 7.6 11.6 5.0 7.6 0.0 0.0 19.6 0.0 16.5 0.0 0.0 4.0 0.5 3.3 0.0 3.2 35.9 0.0 0.0 1.9 0.0 0.0 13.6 0.0 8.4 0.4 0.0 10.8 0.0 0.1 0.0 1.3 0.0 0.0 0.0 2.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 11.1 6.0 0.0 0.0 0.0 7.8 0.0 0.0 1.2 0.4 0.0 0.9 0.0 3.8 0.0 6.3 0.7 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 13.2 93.1 8.7 13.1 2.3 1.4 12.8 4.6 4.2 3.6 1.2 44.9 0.0 1.1 90.8 0.1 6.2 0.2 0.0 0.6 142.1 1.2 5.1 46.0 0.0 0.6 0.0 16.7 1.1 0.5 0.2 1.9 0.0 2.6 1.1 65.8 64.3 47.7 2.7 196.9 0.2 0.3 77.7 0.5 1.1 1.3 2.1 124.2 1.5 1.9 35.3 326.3 0.6 0.0 4.1 9.4 7.5 96.3 1.2 10.6 103.0 0.0 3.9 0.0 262.4 17.3 0.2 0.0 98.9 0.0 0.3 0.0 0.1 0.0 7.2 65.7 24.4 43.1 3.3 16.8 0.9 4.8 1.1 1.1 20.7 0.0 0.1 RWDD2B "C21orf6, GL011" ENSG00000156253 "RWD domain containing 2B" P57060 21 29004384-29019360 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Spermatocytes: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "basophil: 3.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA018316 Uncertain NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "HPA018316: AB_1845702" "unprognostic (1.96e-1)" "unprognostic (1.89e-2)" "unprognostic (1.42e-1)" "unprognostic (6.14e-2)" "unprognostic (6.67e-2)" "unprognostic (5.02e-2)" "unprognostic (1.75e-1)" "unprognostic (2.52e-2)" "unprognostic (1.80e-2)" "unprognostic (3.92e-2)" "unprognostic (2.07e-1)" "unprognostic (2.15e-1)" "unprognostic (1.16e-1)" "unprognostic (6.77e-2)" "unprognostic (2.38e-1)" "unprognostic (1.98e-1)" "unprognostic (2.75e-2)" 0.6 0.9 0.6 0.5 0.5 0.3 0.7 0.9 1.0 0.7 0.2 0.6 0.3 0.6 1.0 0.7 0.6 0.7 1.4 0.7 0.4 0.9 1.2 0.5 1.0 0.8 0.4 0.5 0.8 1.0 0.7 0.6 0.7 0.7 0.7 1.1 0.9 0.7 3.5 1.2 0.4 0.8 0.2 0.6 0.6 0.9 0.6 0.6 1.0 2.9 0.8 0.6 0.4 1.1 1.2 0.6 1.0 1.6 4.6 1.9 0.2 1.2 1.9 1.6 1.9 1.4 1.0 2.1 1.3 2.1 1.0 0.7 1.4 1.4 1.4 1.3 1.0 3.0 0.7 1.0 2.4 0.3 0.1 2.1 1.3 1.8 2.5 1.7 2.0 0.9 1.2 2.0 2.2 2.4 0.6 1.2 1.4 3.4 1.1 0.4 1.2 2.8 1.7 1.4 1.8 2.6 3.0 1.6 3.2 0.7 2.8 1.7 1.5 2.1 1.2 1.5 0.5 2.7 2.7 1.2 1.7 1.9 1.9 3.0 0.4 0.3 0.6 0.3 0.4 0.8 0.3 0.5 0.3 0.6 0.2 0.4 1.1 0.4 0.7 0.5 0.1 0.3 0.6 0.5 0.9 1.0 0.7 0.4 0.8 0.4 0.7 0.2 0.6 1.1 9.0 16.0 14.3 2.6 5.3 3.3 3.2 12.0 7.4 2.4 11.0 11.6 29.9 21.5 7.7 12.9 0.0 12.6 8.7 3.2 29.4 9.0 14.7 6.4 12.9 8.3 12.0 6.5 5.2 9.2 11.2 10.7 7.1 6.1 1.3 5.0 5.7 23.1 8.2 0.0 4.7 7.0 10.2 6.0 3.9 12.5 11.1 4.6 8.8 1.9 12.9 6.9 16.5 5.5 2.9 8.0 8.3 13.5 5.3 4.9 6.7 27.4 4.5 1.3 6.6 10.3 9.6 41.5 17.7 13.2 4.7 6.4 6.2 22.9 6.1 3.3 SAA4 "C-SAA, CSAA" ENSG00000148965 "Serum amyloid A4, constitutive" P35542 11 18231355-18236802 "Plasma proteins, Predicted secreted proteins" "Acute phase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 124 "liver: 1943.5" "Group enriched" "Detected in some" 7 "Hepatocytes: 2132.8;Respiratory ciliated cells: 706.8" "Cancer enriched" "Detected in many" 141 "liver cancer: 118.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 22 "Hep G2: 28.8" "Not detected" "Not detected" "CAB026061, HPA060139" Supported "Secreted to blood" NA NA 65000000000 33000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB026061: , HPA060139: AB_2684210" "unprognostic (4.70e-4)" "unprognostic (1.17e-1)" "unprognostic (1.17e-1)" "unprognostic (4.83e-1)" "unprognostic (4.15e-2)" "unprognostic (6.05e-2)" "unprognostic (3.63e-3)" "unprognostic (5.94e-2)" "unprognostic (2.40e-2)" "unprognostic (1.41e-1)" "unprognostic (7.35e-2)" "unprognostic (2.54e-8)" "unprognostic (2.49e-1)" "unprognostic (6.46e-2)" 7.4 0.5 0.3 0.4 0.3 0.0 6.7 0.3 0.6 15.6 0.3 0.2 0.0 0.0 0.2 0.5 0.5 1.0 0.1 0.3 0.3 0.4 1943.5 0.7 0.0 0.4 0.4 0.0 0.1 0.0 0.8 0.0 0.3 1.2 0.0 0.1 11.4 0.1 3.4 0.5 0.1 0.1 0.3 1.2 0.1 1.3 0.4 0.9 0.0 0.0 0.2 0.1 0.1 0.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.5 0.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.3 0.1 28.8 0.3 0.2 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.6 0.3 0.3 0.4 0.4 0.3 0.3 0.4 0.5 0.1 0.0 0.0 0.0 2.5 0.0 0.0 184.7 0.0 0.0 2.1 1.4 0.0 18.6 172.6 0.0 0.0 0.0 0.0 3.5 0.0 4.0 0.6 0.4 0.0 1.6 0.0 21.5 0.0 1.2 0.1 0.0 0.0 0.3 0.0 0.0 27.5 2132.8 0.1 0.0 0.0 0.0 71.2 38.0 0.0 0.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.3 0.0 0.0 706.8 0.0 0.0 0.0 23.6 0.1 0.0 0.0 0.1 0.0 1.9 0.0 0.2 0.5 SAMD3 "bA73O6.2, FLJ34032" ENSG00000164483 "Sterile alpha motif domain containing 3" Q8N6K7 6 130144315-130365425 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.4" "Cell type enhanced" "Detected in many" "dendritic cells: 157.0;NK-cells: 271.9;Plasma cells: 43.7;T-cells: 84.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 47 "NK-cells: 128.4;T-cells: 113.8" "Cell line enhanced" "Detected in some" "HBF TERT88: 1.8;HDLM-2: 3.4;hTEC/SVTERT24-B: 2.2;hTERT-RPE1: 1.9;NTERA-2: 1.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 2.1" "HPA028992, HPA028993" Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA028992: AB_10598914, HPA028993: AB_10601891" "unprognostic (2.91e-3)" "unprognostic (5.35e-3)" "unprognostic (4.15e-2)" "unprognostic (2.70e-2)" "unprognostic (1.50e-2)" "unprognostic (2.48e-4)" "unprognostic (1.20e-2)" "unprognostic (2.42e-3)" "unprognostic (2.39e-2)" "unprognostic (2.46e-2)" "unprognostic (5.61e-2)" "unprognostic (1.98e-1)" "unprognostic (5.07e-6)" "unprognostic (7.09e-2)" "unprognostic (1.14e-1)" "unprognostic (6.62e-2)" "unprognostic (3.45e-2)" 1.1 2.3 1.4 4.0 2.0 4.2 0.9 0.6 1.6 2.9 0.6 1.2 0.7 4.4 1.9 0.7 1.5 2.3 0.5 2.9 1.2 1.1 1.7 3.3 10.4 0.8 2.0 1.8 1.2 0.1 4.8 0.7 0.9 0.7 2.3 1.4 0.7 0.4 0.8 0.5 1.4 1.7 0.4 9.3 1.6 3.2 1.9 6.3 0.8 0.7 4.2 1.3 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.1 0.3 0.5 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 1.8 3.4 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.3 0.0 2.2 0.1 1.9 0.2 0.4 0.1 0.0 0.2 0.0 0.1 0.0 1.7 0.0 1.1 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.5 113.8 0.4 90.0 2.5 39.8 102.1 0.6 0.3 28.8 68.9 2.3 128.4 0.6 0.6 41.7 41.4 1.4 2.0 0.6 1.6 2.9 1.2 0.8 2.0 0.9 0.4 1.9 0.4 1.1 0.0 2.3 1.3 2.3 0.4 0.0 0.0 0.6 3.0 0.6 0.5 0.8 0.0 0.0 0.0 0.0 0.0 157.0 1.6 0.0 0.2 25.4 1.0 2.1 0.8 3.6 6.6 12.1 0.0 0.0 0.7 0.0 0.5 1.3 14.8 2.9 0.4 0.0 0.0 5.7 0.3 0.0 3.4 1.4 6.7 0.6 1.8 5.4 12.2 2.3 0.0 271.9 1.5 0.6 0.0 1.5 1.9 43.7 0.0 0.1 0.6 0.7 0.4 0.0 0.3 1.4 2.3 1.6 0.2 0.4 0.0 84.3 2.0 0.5 0.1 SAR1B SARA2 ENSG00000152700 "Secretion associated Ras related GTPase 1B" Q9Y6B6 5 134601149-134649271 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 413.3;Hepatocytes: 267.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006923, HPA048368" Supported Approved "Endoplasmic reticulum" NA NA 430000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 16: U-266 - Nucleosome" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Endoplasmic reticulum" "HPA006923: AB_1856577, HPA048368: AB_2680373" "unprognostic (6.14e-2)" "unprognostic (7.33e-2)" "unprognostic (5.32e-2)" "prognostic favorable (7.11e-4)" "unprognostic (1.23e-1)" "unprognostic (5.92e-2)" "prognostic favorable (6.59e-4)" "unprognostic (1.88e-2)" "unprognostic (1.69e-1)" "unprognostic (2.69e-1)" "unprognostic (7.32e-2)" "unprognostic (6.87e-2)" "unprognostic (2.45e-1)" "unprognostic (5.69e-2)" "unprognostic (4.66e-2)" "unprognostic (7.50e-3)" "unprognostic (1.87e-2)" 30.9 46.4 27.5 24.2 40.6 26.0 35.8 40.8 41.7 27.3 40.6 40.9 68.5 14.9 34.9 36.0 17.7 28.2 46.8 31.0 37.5 57.1 163.9 19.7 24.4 43.9 40.5 13.5 32.8 64.9 24.7 20.7 44.7 38.7 36.5 20.3 36.3 29.7 147.5 16.8 69.7 26.7 40.3 20.0 43.4 66.0 35.9 22.7 29.7 140.6 33.6 36.2 20.3 53.9 57.8 49.6 36.0 81.3 111.6 53.4 48.3 95.4 80.0 84.1 127.9 84.3 79.7 31.9 78.3 98.6 116.6 52.1 62.8 92.5 108.0 73.6 37.0 33.6 78.0 81.5 91.7 29.1 44.7 60.4 57.8 97.7 82.7 42.3 64.1 40.9 44.3 71.9 87.0 85.3 38.6 43.6 12.7 70.7 34.4 33.7 62.7 70.2 61.7 91.2 36.8 16.0 67.2 36.1 71.4 47.2 74.2 35.5 51.7 72.8 44.0 66.7 72.3 90.0 215.4 58.7 56.2 55.7 81.6 22.2 70.5 55.0 42.3 71.2 52.9 52.7 48.2 49.7 64.0 34.7 42.9 41.6 25.5 35.8 80.5 43.6 77.1 71.3 27.5 40.6 40.8 41.7 31.0 37.5 43.9 40.5 44.7 40.3 35.9 53.9 49.3 32.1 36.9 21.5 45.6 37.6 44.0 112.9 22.2 30.4 56.0 35.7 86.7 61.5 102.6 57.0 41.7 33.1 44.5 77.0 56.7 47.6 413.3 43.0 51.3 35.3 27.6 44.2 31.6 83.9 43.5 46.1 68.3 45.8 26.6 28.3 38.9 267.7 52.8 33.7 32.8 55.2 89.5 52.9 56.6 76.9 36.7 47.1 64.0 20.6 38.3 41.8 20.6 29.7 66.5 60.4 36.2 44.8 165.8 75.1 210.7 121.4 99.8 40.3 19.7 41.2 47.7 106.8 47.3 51.1 51.1 115.2 47.0 43.0 46.3 96.5 SBNO2 "FLJ00173, KIAA0963, Sno, Stno" ENSG00000064932 "Strawberry notch homolog 2" Q9Y2G9 19 1107637-1174268 "Predicted intracellular proteins" "Differentiation, Osteogenesis, Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "neutrophil: 2.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 2.5" "Cell line enhanced" "Detected in many" "A-431: 45.3;HDLM-2: 65.2;U-266/70: 49.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041867 Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 72: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" "HPA041867: AB_2677715" "unprognostic (1.62e-1)" "unprognostic (1.18e-1)" "unprognostic (1.85e-1)" "unprognostic (6.20e-3)" "unprognostic (4.68e-2)" "unprognostic (8.48e-3)" "unprognostic (1.19e-2)" "unprognostic (1.64e-2)" "unprognostic (1.70e-1)" "unprognostic (1.58e-3)" "unprognostic (3.22e-2)" "unprognostic (2.47e-1)" "prognostic unfavorable (7.98e-8)" "unprognostic (1.34e-2)" "unprognostic (5.67e-2)" "unprognostic (1.35e-1)" "unprognostic (1.88e-1)" 61.3 42.8 2.8 8.5 2.9 11.4 40.2 1.8 5.0 35.7 4.6 31.8 1.9 28.0 0.2 51.8 33.8 3.0 27.1 0.9 3.2 57.8 41.5 68.4 2.7 12.0 5.4 30.9 21.4 0.2 37.8 2.4 5.4 42.7 0.3 0.1 42.9 0.7 38.6 43.0 30.8 2.1 3.5 60.0 30.0 19.3 8.6 1.5 34.2 0.5 2.5 32.1 35.7 5.5 45.3 5.7 0.8 0.5 0.1 2.8 16.1 13.0 1.4 2.9 1.6 0.3 7.3 9.0 18.2 2.2 2.3 14.6 0.0 2.0 1.0 65.2 9.8 9.9 18.3 0.1 2.4 5.8 28.7 6.8 1.8 4.3 1.7 2.2 2.8 3.9 15.3 12.4 1.1 5.5 5.7 7.4 12.3 0.9 19.1 13.1 7.9 11.0 4.0 2.1 10.3 16.1 7.9 14.2 15.8 1.1 5.0 4.6 15.0 7.9 6.2 23.6 22.1 49.0 24.8 7.8 15.7 5.3 9.0 0.0 0.3 0.1 0.1 0.2 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 2.5 0.1 0.1 0.1 0.0 0.1 2.8 2.9 1.8 5.0 0.9 3.2 12.0 5.4 5.4 3.5 8.6 5.5 28.8 9.6 22.8 4.6 8.8 14.9 13.2 10.7 11.4 5.7 39.7 23.9 5.4 5.7 18.8 3.7 2.1 4.7 13.2 22.3 3.9 9.4 2.8 19.3 21.9 25.3 3.0 0.4 4.4 6.8 5.7 13.1 33.6 39.1 3.8 10.4 13.9 10.8 10.3 6.7 3.4 10.2 14.2 15.9 20.7 1.6 9.3 20.2 8.8 5.6 13.0 3.3 5.2 3.5 5.8 17.9 15.1 4.1 16.2 20.8 7.9 1.8 14.5 4.9 6.6 12.0 12.9 7.7 9.0 10.6 18.8 10.9 14.4 9.5 12.3 22.1 SCAI "C9orf126, FLJ36664, NET40" ENSG00000173611 "Suppressor of cancer cell invasion" Q8N9R8 9 124942608-125143528 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Repressor, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 11.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 200.1;Excitatory neurons: 327.4;Inhibitory neurons: 171.6;Rod photoreceptor cells: 136.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020632 Approved Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nuclear membrane" "HPA020632: AB_1845804" "unprognostic (1.93e-1)" "unprognostic (1.88e-2)" "unprognostic (1.42e-1)" "unprognostic (2.93e-2)" "unprognostic (6.90e-2)" "unprognostic (3.34e-3)" "unprognostic (7.75e-2)" "unprognostic (4.54e-3)" "unprognostic (5.69e-2)" "unprognostic (2.78e-1)" "unprognostic (4.72e-3)" "unprognostic (1.47e-1)" "unprognostic (1.87e-2)" "unprognostic (3.57e-2)" "unprognostic (6.40e-2)" "unprognostic (1.96e-1)" "unprognostic (1.26e-3)" 1.7 2.5 3.3 1.8 3.7 2.9 1.9 0.3 4.2 2.1 5.2 1.9 1.1 2.1 1.5 1.4 2.1 1.2 1.3 2.4 0.3 1.5 1.5 3.2 2.9 0.0 0.4 2.7 1.7 1.5 1.7 0.9 0.0 1.9 1.7 7.5 1.4 1.0 1.7 2.4 1.5 1.3 0.0 1.9 1.5 1.9 0.9 11.2 1.9 1.0 2.3 1.5 1.7 0.9 3.2 2.4 3.2 3.1 1.7 4.2 5.4 2.0 4.1 2.1 2.9 3.1 3.0 5.7 1.5 2.0 2.4 5.3 4.2 2.2 4.2 4.1 1.5 3.8 4.4 2.8 2.4 4.0 2.8 1.6 1.8 3.2 2.1 3.5 3.0 10.2 5.4 6.6 3.2 3.5 13.0 2.8 3.2 6.1 2.6 8.1 5.1 5.0 1.4 4.3 3.3 2.1 4.7 2.5 2.4 3.5 6.3 1.8 3.1 1.9 3.5 3.2 3.5 3.6 7.3 5.5 2.2 3.3 2.8 0.2 0.3 0.0 0.2 0.4 0.3 0.5 0.4 0.3 0.2 0.6 0.6 0.4 0.2 0.6 0.1 0.8 0.7 0.3 3.3 3.7 0.3 4.2 2.4 0.3 0.0 0.4 0.0 0.0 0.9 0.9 7.3 70.5 28.2 49.0 19.7 2.8 7.9 6.0 10.2 46.4 8.7 5.6 4.8 14.3 9.4 18.4 200.1 6.6 14.6 6.3 1.9 4.1 14.5 9.4 8.5 8.0 13.1 23.3 327.4 2.0 4.7 7.5 8.2 14.2 5.1 74.5 12.5 8.7 4.2 16.8 171.6 8.4 16.2 6.6 5.5 5.9 9.6 5.4 3.6 55.3 5.4 25.8 22.6 72.9 61.0 2.9 7.3 6.0 14.3 9.6 8.3 3.1 10.3 136.5 0.0 11.3 8.3 34.7 21.5 12.4 4.3 2.6 14.8 28.9 11.2 4.4 SCARB2 "CD36L2, HLGP85, LIMP-2, LIMPII, SR-BII" ENSG00000138760 "Scavenger receptor class B member 2" Q14108 4 76158737-76234536 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 12.5;classical monocyte: 14.1;intermediate monocyte: 26.0;myeloid DC: 8.2;non-classical monocyte: 24.9;plasmacytoid DC: 28.9" "Group enriched" "Detected in all" 5 "dendritic cells: 28.9;granulocytes: 12.5;monocytes: 26.0" "Cell line enhanced" "Detected in many" "ASC diff: 499.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015415, HPA018014" Supported Approved Cytosol NA NA 9200 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 35: Glandular cells - Unknown function" Cytosol "CAB015415: AB_831511, HPA018014: AB_1852881" "prognostic unfavorable (2.82e-5)" "unprognostic (2.73e-2)" "unprognostic (4.09e-2)" "unprognostic (4.96e-2)" "unprognostic (4.17e-3)" "unprognostic (1.12e-3)" "unprognostic (2.08e-1)" "unprognostic (5.48e-2)" "unprognostic (4.06e-1)" "unprognostic (1.25e-2)" "unprognostic (4.11e-2)" "unprognostic (1.67e-1)" "unprognostic (1.91e-2)" "unprognostic (1.17e-1)" "unprognostic (6.88e-2)" "unprognostic (5.06e-2)" "unprognostic (3.89e-2)" 60.6 24.0 33.5 27.7 63.5 7.3 56.7 58.9 38.9 60.8 18.9 61.6 39.2 44.1 58.4 33.9 45.4 60.0 61.6 29.6 48.6 46.8 89.9 77.1 20.2 62.2 49.6 58.9 58.9 63.6 11.1 80.2 62.5 72.3 64.0 53.2 80.5 55.4 89.8 26.0 49.1 57.8 60.1 47.0 60.7 19.4 50.7 21.3 65.9 81.3 20.6 65.3 25.1 92.9 39.8 38.4 48.9 97.1 499.7 242.0 35.8 131.5 250.2 114.0 178.2 72.5 112.3 0.0 85.1 262.3 109.6 28.3 28.3 78.9 96.0 138.8 30.1 3.2 32.9 25.3 129.9 19.0 12.1 186.9 72.3 117.3 54.5 268.9 200.6 10.0 15.6 188.6 159.2 58.2 1.6 4.0 9.7 120.3 23.6 23.3 82.7 42.0 64.4 43.6 101.3 110.2 104.7 61.3 115.5 49.3 34.6 17.1 131.3 125.9 48.5 104.7 47.5 167.6 98.8 0.2 158.1 22.2 170.9 12.5 14.1 3.1 2.8 26.0 2.6 3.8 1.9 1.5 8.2 3.0 2.6 4.3 1.9 1.1 24.9 28.9 3.0 6.1 33.5 63.5 58.9 38.9 29.6 48.6 62.2 49.6 62.5 60.1 50.7 92.9 89.0 176.3 52.4 47.3 20.1 24.0 90.5 64.8 34.1 109.6 69.7 36.4 53.0 87.2 52.1 99.3 60.5 35.3 43.6 109.0 7.9 119.9 7.1 50.3 74.0 69.9 102.4 28.6 57.4 72.9 47.5 108.3 40.8 88.8 3.8 84.8 79.6 108.7 143.4 60.6 55.4 77.1 44.7 165.7 27.5 5.6 45.4 76.2 67.6 38.4 43.5 87.2 6.2 106.1 201.1 78.0 68.3 66.5 82.2 133.5 103.2 27.6 54.4 81.7 92.1 91.0 68.1 18.2 16.5 34.8 33.8 59.4 16.3 56.5 55.3 93.4 SCIMP "C17orf87, DTFT5783, FLJ32580, MGC163426, MGC163428, UNQ5783" ENSG00000161929 "SLP adaptor and CSK interacting membrane protein" Q6UWF3 17 5208920-5234860 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 49.2" "Cell type enhanced" "Detected in many" "B-cells: 66.4;Hofbauer cells: 26.2;Kupffer cells: 120.3;Macrophages: 66.3;monocytes: 60.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 2.7" "Group enriched" "Detected in many" 8 "classical monocyte: 110.6;intermediate monocyte: 239.0;memory B-cell: 145.8;myeloid DC: 84.2;naive B-cell: 124.5;non-classical monocyte: 265.5" "Group enriched" "Detected in all" 9 "B-cells: 145.8;dendritic cells: 84.2;monocytes: 265.5" "Cell line enhanced" "Detected in many" "HeLa: 6.8;U-698: 10.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006117 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA006117: AB_1858633" "unprognostic (2.53e-2)" "unprognostic (7.88e-3)" "unprognostic (1.26e-2)" "unprognostic (5.79e-3)" "unprognostic (1.10e-1)" "unprognostic (3.87e-2)" "unprognostic (7.96e-2)" "unprognostic (1.73e-2)" "unprognostic (4.93e-2)" "unprognostic (2.99e-1)" "unprognostic (1.35e-1)" "unprognostic (8.05e-2)" "unprognostic (3.33e-2)" "unprognostic (2.07e-1)" "unprognostic (4.42e-2)" "unprognostic (1.77e-1)" "unprognostic (9.95e-2)" 5.9 4.1 0.0 30.4 0.1 5.1 1.4 2.7 1.3 1.5 3.6 4.5 5.4 2.9 1.1 1.9 3.1 7.3 1.7 0.3 0.0 2.3 10.6 16.2 39.4 0.6 0.1 3.6 3.9 0.8 0.7 3.9 0.1 3.1 4.6 7.5 4.0 1.4 4.3 3.2 10.2 6.1 0.0 49.2 5.0 2.8 0.0 5.1 3.4 0.8 44.9 6.0 0.6 0.4 1.0 1.5 2.5 3.3 0.0 0.0 2.5 1.1 0.0 0.0 0.0 0.7 2.1 4.8 0.9 0.0 1.8 1.0 0.0 0.0 0.0 0.8 2.1 2.0 6.8 0.7 0.0 0.2 0.7 0.0 0.1 0.0 0.2 1.2 0.0 4.2 0.1 1.2 0.0 1.6 2.4 0.7 1.1 0.3 1.4 2.2 0.5 0.5 0.0 0.6 1.8 0.8 1.8 0.6 1.3 0.7 2.6 2.4 0.3 0.3 1.1 1.4 0.6 0.7 0.3 10.8 1.2 0.3 0.7 16.8 110.6 3.0 1.3 239.0 1.5 145.8 0.8 1.2 84.2 124.5 1.7 1.2 19.0 5.3 265.5 3.2 1.4 68.0 0.0 0.1 2.7 1.3 0.3 0.0 0.6 0.1 0.1 0.0 0.0 0.4 0.5 0.0 4.4 2.6 66.4 0.4 0.4 0.0 0.0 2.5 0.4 0.5 0.4 1.5 0.6 0.0 12.5 0.3 1.5 0.0 0.0 0.7 1.4 0.4 0.3 2.0 0.0 0.4 6.5 0.9 0.3 0.6 0.0 0.1 1.3 0.4 3.3 1.9 26.2 1.7 4.9 0.0 0.0 120.3 4.2 0.7 0.3 66.3 0.0 8.4 60.3 0.4 10.3 4.0 2.3 0.4 0.0 0.4 1.7 0.3 0.0 1.0 1.6 4.1 0.0 0.7 0.3 0.5 0.8 0.0 0.4 0.1 3.2 0.2 0.0 0.4 SCNN1D "dNaCh, ENaCdelta" ENSG00000162572 "Sodium channel epithelial 1 subunit delta" P51172 1 1280436-1292029 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 35.5" "Cell type enhanced" "Detected in many" "Astrocytes: 10.7;Early spermatids: 10.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/70: 9.3" "Low region specificity" "Detected in all" HPA026884 Enhanced Supported "Plasma membrane,Actin filaments" NA NA "Cluster 43: Testis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Actin filaments" "HPA026884: AB_10601501" "unprognostic (2.08e-2)" "unprognostic (2.08e-1)" "unprognostic (7.39e-4)" "unprognostic (1.06e-2)" "unprognostic (2.74e-1)" "prognostic favorable (1.60e-4)" "unprognostic (1.44e-2)" "unprognostic (1.81e-1)" "unprognostic (2.08e-2)" "unprognostic (1.14e-1)" "prognostic favorable (1.32e-4)" "unprognostic (5.27e-2)" "prognostic unfavorable (6.67e-5)" "unprognostic (3.13e-1)" "unprognostic (4.18e-2)" "unprognostic (2.13e-1)" "unprognostic (7.06e-2)" 5.6 7.1 10.3 1.7 10.4 3.2 6.0 11.7 18.1 11.1 5.9 9.4 5.2 8.0 0.9 4.0 14.0 1.2 6.2 9.7 7.5 7.7 13.7 3.7 2.3 10.7 8.5 14.7 4.8 0.7 18.5 1.1 10.9 9.7 0.3 1.7 5.8 1.7 3.4 4.7 7.6 0.8 6.9 8.0 6.3 35.5 9.9 0.9 6.3 1.4 0.7 5.1 7.6 11.7 0.5 4.2 1.6 4.3 1.1 0.6 0.7 2.8 0.8 1.3 1.5 0.8 2.4 3.0 1.5 1.2 2.2 0.7 0.7 0.6 0.2 5.8 2.5 0.4 5.9 1.1 1.1 0.1 2.9 1.8 0.9 2.3 0.0 1.8 0.4 5.5 2.1 7.0 0.3 1.5 1.2 2.0 0.8 0.5 3.0 8.1 0.3 0.7 0.6 0.2 2.2 3.1 1.2 1.2 1.9 0.6 5.4 1.6 1.2 2.6 2.1 4.1 0.9 9.3 0.6 2.5 2.3 5.2 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 10.4 11.7 18.1 9.7 7.5 10.7 8.5 10.9 6.9 9.9 11.7 1.7 3.2 2.3 10.7 1.0 0.8 0.2 1.2 1.2 3.7 2.2 3.4 4.0 0.0 1.7 0.0 4.2 0.1 0.6 1.0 0.0 0.5 10.5 0.6 2.1 0.6 1.2 2.7 5.2 0.5 0.4 1.7 4.1 1.3 2.5 3.2 0.7 3.5 0.4 5.0 6.0 0.4 0.0 0.8 0.5 4.0 0.9 1.1 0.0 1.0 0.1 1.4 0.0 4.5 5.4 2.0 3.8 1.9 0.7 0.1 3.9 0.7 1.9 2.8 0.0 1.8 1.5 2.8 2.2 0.8 1.6 0.0 1.0 0.5 0.9 0.3 SCYL3 "PACE-1, PACE1" ENSG00000000457 "SCY1 like pseudokinase 3" Q8IZE3 1 169849631-169894267 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005624 Approved Uncertain "Nuclear bodies,Microtubules" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 52: Non-specific - Transcription" Microtubules "Nuclear bodies" "HPA005624: AB_1854916" "unprognostic (2.35e-1)" "unprognostic (1.25e-1)" "unprognostic (7.53e-2)" "unprognostic (8.36e-2)" "unprognostic (7.13e-2)" "unprognostic (2.72e-3)" "unprognostic (1.31e-1)" "unprognostic (2.12e-2)" "unprognostic (2.85e-2)" "unprognostic (7.17e-2)" "unprognostic (8.80e-2)" "unprognostic (9.88e-2)" "unprognostic (1.20e-3)" "unprognostic (3.54e-1)" "unprognostic (1.75e-1)" "unprognostic (4.60e-2)" "prognostic favorable (8.85e-4)" 5.6 5.8 2.7 7.4 3.0 4.0 10.9 4.0 3.5 6.7 5.0 7.8 7.7 7.0 8.3 7.3 6.3 7.6 5.2 3.0 3.0 7.5 11.3 6.2 10.5 2.9 2.8 7.6 6.1 12.0 4.1 8.1 3.1 7.6 9.6 11.4 8.2 6.7 7.9 7.7 6.8 6.2 2.9 7.5 7.7 6.6 3.0 9.7 7.6 9.1 9.8 7.3 6.5 3.9 4.1 5.2 7.9 5.5 9.9 7.2 9.1 6.3 8.1 7.2 6.7 4.8 7.7 8.4 4.5 6.5 4.0 9.4 4.7 5.5 6.4 15.5 4.4 5.8 6.1 3.1 7.0 8.5 7.3 7.0 5.4 5.0 6.8 6.7 6.9 9.2 9.4 10.8 6.9 3.2 6.9 6.5 6.4 27.5 2.5 6.3 4.3 10.1 7.6 7.3 5.9 8.6 5.0 16.3 10.1 11.2 9.1 7.8 5.2 5.1 3.4 6.2 5.1 14.4 13.7 9.9 3.9 6.3 5.7 13.5 3.2 8.6 6.3 3.4 8.5 6.7 8.3 7.0 5.1 6.2 7.0 5.8 6.7 10.7 3.8 11.5 8.1 4.8 2.7 3.0 4.0 3.5 3.0 3.0 2.9 2.8 3.1 2.9 3.0 3.9 5.9 6.4 14.4 11.8 9.6 2.4 2.5 3.6 6.2 10.2 9.6 8.3 4.2 22.8 7.8 1.8 10.4 17.6 19.0 14.0 9.8 7.4 5.1 11.1 8.2 6.6 9.1 4.2 15.8 9.1 5.1 5.1 7.1 5.8 5.7 7.2 11.0 13.2 6.5 10.1 12.5 10.4 8.2 11.4 3.5 2.6 4.4 5.3 1.8 9.4 8.4 10.0 16.5 17.6 14.1 6.2 10.2 5.7 10.5 4.7 13.3 6.4 9.0 19.9 6.6 5.5 5.4 10.9 6.8 8.3 1.8 11.6 11.0 6.3 10.3 3.3 SDC3 "N-syndecan, SYND3" ENSG00000162512 "Syndecan 3" O75056 1 30869466-30908758 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 140.3" "Cell type enhanced" "Detected in many" "Astrocytes: 64.6;Endometrial stromal cells: 59.8;Kupffer cells: 174.8;Late spermatids: 82.4;Oligodendrocyte precursor cells: 108.6" "Group enriched" "Detected in all" 5 "glioma: 115.2;melanoma: 102.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SK-MEL-30: 249.5;WM-115: 342.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017087, CAB025786, HPA048085" Approved Approved Nucleoplasm,Mitochondria Yes No "Cluster 42: Non-specific - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria Nucleoplasm "CAB025786: , HPA017087: AB_1857706, HPA048085: AB_2680256" "unprognostic (1.42e-3)" "unprognostic (5.52e-2)" "unprognostic (1.20e-1)" "unprognostic (4.55e-2)" "unprognostic (1.79e-2)" "unprognostic (1.87e-1)" "unprognostic (1.79e-3)" "unprognostic (2.83e-1)" "prognostic favorable (2.36e-4)" "unprognostic (9.77e-2)" "unprognostic (5.14e-2)" "unprognostic (1.65e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (6.45e-2)" "unprognostic (2.74e-1)" "unprognostic (9.80e-3)" "unprognostic (1.46e-1)" 33.9 99.1 103.9 22.9 123.9 3.0 17.9 97.0 105.4 36.5 38.1 57.3 12.3 62.3 12.3 17.6 29.8 30.0 22.7 91.6 111.1 10.4 22.3 22.5 36.4 140.3 121.2 9.3 7.5 13.2 11.8 18.1 107.9 26.9 14.6 27.2 15.9 52.7 27.1 10.1 16.5 66.2 112.4 91.0 19.7 3.3 124.4 6.4 9.8 9.1 7.6 32.7 13.4 91.9 12.9 10.4 80.4 36.5 60.6 14.8 13.8 31.4 48.0 15.0 9.5 2.0 12.3 0.9 68.6 95.3 21.8 16.3 8.7 7.6 10.0 5.7 6.3 0.0 4.1 1.8 56.9 0.3 8.2 35.4 35.9 1.0 15.4 86.6 20.1 3.6 6.2 0.5 30.6 15.0 0.3 0.2 36.4 10.2 9.4 0.8 75.2 2.8 19.7 14.9 28.9 17.5 40.3 5.7 249.5 50.8 5.7 6.1 19.3 18.6 28.2 2.0 7.5 0.1 0.5 0.9 1.9 0.2 342.9 1.1 0.3 0.2 0.1 0.6 0.2 0.1 0.1 0.2 0.2 0.2 0.2 0.2 0.5 0.4 0.4 0.2 0.2 0.2 103.9 123.9 97.0 105.4 91.6 111.1 140.3 121.2 107.9 112.4 124.4 91.9 37.3 0.0 2.2 64.6 0.5 2.5 3.4 4.7 4.0 9.6 14.9 25.5 4.9 14.3 2.6 47.8 0.0 2.1 0.2 0.8 0.0 10.7 17.7 14.1 59.8 17.9 3.0 0.0 14.7 3.1 3.4 16.6 3.1 28.6 0.0 17.5 20.3 1.0 14.3 0.0 13.9 1.1 6.1 174.8 3.1 82.4 2.1 24.4 19.6 18.7 4.0 2.5 1.0 108.6 6.8 6.0 1.3 7.9 1.5 8.5 0.0 0.6 0.4 27.8 0.0 1.1 9.1 0.7 0.4 1.3 2.3 3.6 2.3 15.4 1.6 5.7 SDHA "FP, SDH2, SDHF" ENSG00000073578 "Succinate dehydrogenase complex flavoprotein subunit A" P31040 5 218241-257082 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Cardiomyopathy, Disease variant, FDA approved drug targets, Leigh syndrome, Primary mitochondrial disease, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 601.0;skeletal muscle: 479.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB034929, HPA041981, HPA064582" Enhanced Supported Nucleoli,Mitochondria No No 360000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoli "CAB034929: AB_2183443, HPA041981: AB_2677779, HPA064582: AB_2685293" "prognostic unfavorable (6.00e-4)" "unprognostic (1.93e-1)" "unprognostic (5.97e-2)" "unprognostic (1.36e-1)" "unprognostic (1.89e-1)" "unprognostic (1.62e-1)" "unprognostic (2.80e-1)" "unprognostic (3.14e-2)" "unprognostic (2.88e-1)" "unprognostic (1.67e-2)" "unprognostic (1.97e-1)" "unprognostic (1.24e-1)" "prognostic favorable (9.53e-8)" "unprognostic (1.11e-2)" "unprognostic (2.62e-1)" "unprognostic (3.57e-1)" "unprognostic (1.79e-1)" 70.6 148.0 60.5 29.6 62.7 38.4 65.8 78.7 71.3 50.2 63.2 131.9 148.9 53.2 27.3 67.1 50.3 33.9 601.0 60.8 73.4 139.1 276.8 54.3 43.1 74.1 62.7 65.8 71.5 122.9 44.8 28.8 75.7 46.3 82.1 42.7 66.8 35.6 479.0 58.9 116.8 36.1 61.7 66.4 115.6 56.4 71.7 41.8 49.6 224.8 36.5 63.2 56.3 63.7 88.4 154.2 54.8 95.0 96.9 68.5 154.1 63.3 81.8 107.2 108.4 163.9 115.9 108.3 218.6 70.2 92.1 111.8 102.4 129.7 66.3 241.9 98.9 50.1 390.8 224.1 60.0 69.5 70.7 70.6 84.3 83.6 33.7 93.6 123.9 83.5 84.6 83.1 48.7 155.8 93.9 206.9 19.3 101.4 193.5 119.0 84.6 223.2 245.4 122.7 62.3 35.4 332.5 205.5 90.7 36.1 115.0 93.2 91.1 80.3 82.1 48.2 52.5 93.0 40.9 79.8 81.6 99.9 52.5 66.6 70.8 88.1 95.2 85.7 86.8 79.5 92.5 94.5 93.3 73.3 89.2 85.0 14.1 85.5 74.7 59.5 149.3 111.3 60.5 62.7 78.7 71.3 60.8 73.4 74.1 62.7 75.7 61.7 71.7 63.7 29.4 35.3 71.1 20.2 50.9 61.2 81.4 105.8 31.3 51.0 24.6 17.0 272.6 64.3 78.5 75.4 102.2 109.6 39.3 169.7 142.8 94.7 58.7 39.1 30.1 39.1 47.5 56.8 34.4 44.9 102.8 49.4 47.9 48.5 43.7 64.8 47.5 167.0 67.5 101.0 39.9 96.3 105.8 41.0 55.0 28.8 68.3 38.8 90.7 12.2 60.2 50.7 52.5 19.1 37.9 54.2 100.1 55.7 67.5 37.0 274.4 190.7 75.2 87.2 78.9 33.2 51.7 96.9 54.3 40.9 35.9 154.7 56.7 85.0 160.1 88.2 SDHAF3 "ACN9, DC11, LYRM10, Sdh7" ENSG00000196636 "Succinate dehydrogenase complex assembly factor 3" Q9NRP4 7 97117698-97181763 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 148.7;Early spermatids: 136.0;Proximal tubular cells: 150.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA020515, HPA020523" Approved Approved Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA020515: , HPA020523: AB_2670464" "unprognostic (3.94e-2)" "unprognostic (9.11e-2)" "unprognostic (6.51e-2)" "unprognostic (2.51e-2)" "unprognostic (1.39e-1)" "unprognostic (1.61e-2)" "unprognostic (9.60e-3)" "unprognostic (3.21e-2)" "unprognostic (3.74e-2)" "unprognostic (3.07e-3)" "unprognostic (4.27e-2)" "unprognostic (1.10e-1)" "unprognostic (7.67e-3)" "unprognostic (2.82e-1)" "unprognostic (3.79e-3)" "unprognostic (2.34e-1)" "unprognostic (8.45e-2)" 12.4 17.5 9.3 12.4 9.8 16.7 18.7 10.5 13.3 15.0 13.5 20.7 19.9 12.4 22.2 15.0 14.6 13.0 27.0 9.4 11.2 33.5 32.1 8.4 18.5 10.6 10.4 10.7 18.4 12.2 3.6 9.6 11.0 14.8 20.3 16.4 22.0 12.0 29.0 14.1 17.4 12.2 11.6 11.2 18.3 14.5 10.2 24.5 19.0 25.6 14.5 12.8 3.7 12.1 36.6 27.6 24.5 82.3 15.8 12.8 14.8 15.8 7.6 15.6 22.8 5.0 30.7 57.4 40.1 14.1 20.7 13.4 49.6 38.8 33.7 44.2 59.6 34.6 24.8 54.8 23.8 89.4 16.0 24.3 30.3 25.7 32.0 11.6 14.5 57.2 99.5 1.6 34.8 0.0 94.5 126.7 37.3 74.1 34.6 21.0 14.0 83.7 26.0 24.9 63.8 40.7 38.5 47.9 55.5 33.9 0.4 31.6 16.0 4.2 53.2 88.6 10.7 41.4 87.0 139.5 14.6 144.7 51.9 30.0 21.4 8.0 26.5 26.3 36.3 36.3 33.3 39.1 27.9 32.1 45.9 44.4 20.2 23.9 26.7 82.6 33.2 37.9 9.3 9.8 10.5 13.3 9.4 11.2 10.6 10.4 11.0 11.6 10.2 12.1 24.4 19.2 12.5 8.5 34.4 0.0 23.1 0.0 29.0 13.8 38.6 44.4 37.9 18.6 6.8 25.8 4.2 35.2 31.3 7.2 148.7 30.6 136.0 31.3 20.6 17.3 13.3 32.6 16.6 39.1 30.0 20.1 29.0 21.4 5.1 22.2 16.4 55.9 31.1 10.1 14.3 24.2 0.0 20.1 0.0 20.7 22.7 20.2 0.0 9.4 13.9 44.8 36.0 14.6 18.5 24.0 29.1 24.8 30.9 17.0 35.1 150.9 16.0 19.5 32.9 19.5 20.4 32.7 49.3 53.5 0.0 9.6 26.3 45.6 39.8 25.0 SDHB "SDH, SDH1" ENSG00000117118 "Succinate dehydrogenase complex iron sulfur subunit B" P21912 1 17018722-17054032 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 491.5;tongue: 580.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 405.5;Proximal tubular cells: 449.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002868, CAB009822, CAB068233, CAB068234, CAB068235" Enhanced Supported "Nucleoplasm,Plasma membrane,Mitochondria" "Intracellular and membrane" NA NA 7900 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Plasma membrane" "CAB009822: AB_2183458, CAB068233: AB_2665638, CAB068234: AB_2665639, CAB068235: AB_2665640, HPA002868: AB_1079889" "unprognostic (1.06e-1)" "unprognostic (2.86e-2)" "unprognostic (2.19e-2)" "unprognostic (2.93e-2)" "unprognostic (1.88e-1)" "unprognostic (2.79e-3)" "unprognostic (1.58e-1)" "unprognostic (3.02e-1)" "unprognostic (1.19e-1)" "unprognostic (8.45e-2)" "unprognostic (5.51e-2)" "unprognostic (3.93e-2)" "prognostic favorable (2.93e-7)" "unprognostic (1.46e-1)" "unprognostic (2.75e-1)" "unprognostic (7.82e-2)" "unprognostic (3.82e-2)" 85.8 95.7 68.0 59.0 72.2 94.6 68.7 80.6 84.3 56.8 81.1 134.3 163.0 56.0 71.0 77.4 59.8 48.0 302.8 69.9 76.9 228.0 336.1 56.1 75.3 74.8 71.4 44.4 80.3 144.3 42.8 57.6 73.8 55.7 132.4 62.9 74.0 60.5 491.5 55.6 121.9 70.4 73.9 60.5 92.8 64.4 74.9 62.7 64.3 580.6 84.2 71.3 52.0 78.9 157.3 152.7 72.2 107.8 141.6 135.2 95.9 122.4 145.2 254.3 227.7 216.8 183.1 206.8 159.3 156.4 176.1 180.1 290.7 226.8 284.8 128.7 280.6 183.4 149.2 168.2 172.8 276.0 135.6 140.4 154.9 224.5 370.1 138.7 183.6 176.5 165.2 236.9 179.6 129.5 182.4 175.1 70.4 224.6 302.6 146.1 142.5 265.4 252.4 88.7 157.5 86.0 172.3 216.3 392.3 76.4 131.1 169.1 94.9 115.8 131.0 206.4 176.0 98.9 133.3 198.6 170.4 438.5 128.3 68.7 149.8 149.5 71.4 206.5 70.7 89.9 81.0 77.5 186.8 81.1 73.5 74.8 174.3 85.3 185.7 89.3 113.8 116.1 68.0 72.2 80.6 84.3 69.9 76.9 74.8 71.4 73.8 73.9 74.9 78.9 48.2 64.1 47.4 20.9 57.4 52.1 93.3 199.8 40.5 31.5 45.2 49.4 405.5 101.5 97.0 47.8 14.6 107.1 48.3 176.1 354.1 134.3 220.3 48.7 38.2 54.7 48.6 77.3 27.7 149.2 142.2 62.0 46.9 45.5 66.6 39.9 46.8 226.0 177.4 37.0 32.1 103.1 116.0 88.7 67.9 30.5 57.8 78.4 64.0 29.0 123.1 78.3 48.4 15.6 24.6 111.5 218.3 67.7 62.2 74.4 300.5 449.0 79.8 53.8 39.5 57.1 191.6 148.9 71.5 72.9 54.6 121.8 46.8 69.3 162.0 110.9 SEC11C "SEC11L3, SPC21, SPCS4C" ENSG00000166562 "SEC11 homolog C, signal peptidase complex subunit" Q9BY50 18 59139866-59158832 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ionocytes: 685.6;Muller glia cells: 544.7;Plasma cells: 1164.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 523.5;Karpas-707: 546.2;RPMI-8226: 1150.0;U-266/70: 587.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026816, HPA047533" Approved Approved "Nuclear membrane,Golgi apparatus" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 22: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear membrane" "Golgi apparatus" "HPA026816: AB_10602089, HPA047533: AB_2680078" "unprognostic (1.47e-2)" "unprognostic (2.20e-2)" "unprognostic (1.26e-1)" "unprognostic (2.44e-2)" "unprognostic (3.13e-3)" "unprognostic (4.48e-3)" "unprognostic (2.95e-1)" "unprognostic (2.32e-2)" "unprognostic (1.15e-1)" "unprognostic (4.33e-2)" "unprognostic (1.80e-2)" "unprognostic (1.72e-1)" "unprognostic (6.25e-2)" "unprognostic (3.83e-2)" "unprognostic (4.63e-2)" "unprognostic (2.58e-1)" "unprognostic (1.15e-1)" 24.6 76.7 110.0 86.5 117.5 63.1 81.8 122.9 140.5 57.8 94.4 92.3 126.7 40.1 284.6 42.5 41.4 47.3 30.0 112.9 146.4 70.2 219.0 62.7 104.2 137.3 130.2 29.9 374.0 153.9 155.2 28.4 136.8 225.7 78.2 108.1 397.3 62.3 15.7 29.7 97.8 30.1 123.7 81.4 138.5 28.1 113.5 53.0 163.7 20.0 117.8 59.4 21.2 135.8 82.4 100.0 52.9 74.1 31.9 6.8 64.7 72.4 62.9 89.9 55.2 78.3 42.5 176.8 109.9 46.6 67.6 82.8 84.7 59.0 58.4 523.5 113.8 58.5 69.3 242.3 99.3 199.4 87.6 20.4 140.7 56.2 161.1 20.2 33.7 78.4 67.4 546.2 34.6 100.0 79.0 79.2 48.1 140.4 60.5 72.8 50.0 1150.0 67.5 76.1 223.2 90.5 43.1 162.5 252.8 29.9 76.0 148.5 24.7 98.5 45.4 36.5 86.9 587.3 434.4 176.0 99.4 131.8 124.5 76.4 70.7 57.9 146.1 97.6 187.6 197.8 150.4 142.5 78.8 127.9 77.7 105.4 12.2 108.3 108.8 299.6 223.7 222.1 110.0 117.5 122.9 140.5 112.9 146.4 137.3 130.2 136.8 123.7 113.5 135.8 64.8 28.9 120.7 19.2 295.9 32.6 49.3 92.4 12.5 63.6 120.0 128.3 59.3 144.4 102.5 60.7 50.1 70.8 148.7 76.3 88.0 164.4 45.4 58.7 34.2 60.3 339.3 43.8 12.2 263.1 109.1 29.2 60.6 147.1 47.5 21.5 56.4 224.7 112.9 50.5 13.3 223.1 685.6 37.1 56.9 18.8 12.5 63.9 256.1 10.3 46.4 544.7 96.8 17.1 31.2 148.9 78.4 23.0 1164.8 380.9 99.3 118.8 81.3 89.3 6.6 23.1 70.6 110.2 81.5 35.5 45.5 149.7 92.3 40.1 88.3 79.2 SEC14L1 "PRELID4A, SEC14L" ENSG00000129657 "SEC14 like lipid binding 1" Q92503 17 77088749-77217101 "Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 430.3;Hepatic stellate cells: 286.3;Late spermatids: 740.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 355.0" "Lineage enriched" "Detected in all" 11 "granulocytes: 355.0" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 398.1;TIME: 251.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021463, HPA028703" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA021463: AB_2670712, HPA028703: AB_10602300" "unprognostic (1.19e-1)" "unprognostic (8.61e-2)" "unprognostic (1.51e-2)" "unprognostic (4.64e-3)" "unprognostic (1.26e-1)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "unprognostic (1.61e-1)" "unprognostic (7.37e-2)" "unprognostic (1.21e-1)" "unprognostic (7.40e-3)" "unprognostic (1.39e-1)" "unprognostic (1.32e-1)" "unprognostic (1.37e-1)" "unprognostic (1.33e-3)" "unprognostic (3.09e-1)" "unprognostic (4.30e-2)" 66.7 54.2 42.6 44.6 63.3 65.5 57.6 75.4 60.7 39.5 36.3 19.5 21.8 24.6 28.2 31.5 27.3 34.3 50.2 49.5 57.5 42.0 25.3 66.9 49.7 64.0 63.0 20.7 30.8 25.1 27.9 76.7 54.6 18.3 19.8 19.0 35.0 16.8 94.1 20.5 21.7 27.1 46.2 49.9 31.7 51.9 63.6 24.1 41.6 54.7 46.2 26.0 20.6 50.9 55.0 45.4 65.6 105.0 27.4 36.3 24.1 47.4 42.0 57.8 49.5 55.7 39.6 143.1 93.3 65.0 71.1 26.3 36.0 47.8 72.6 27.3 50.1 81.1 42.4 75.9 44.4 26.8 39.8 46.6 20.7 47.8 47.8 69.1 398.1 24.3 55.8 136.0 79.2 36.2 28.5 22.4 25.0 25.7 43.7 20.3 104.2 112.2 91.2 26.2 59.5 44.8 51.1 31.3 32.1 58.3 27.9 20.7 251.1 65.4 60.6 35.0 37.7 71.1 64.8 79.9 27.9 22.1 21.6 33.8 19.4 48.9 7.1 28.3 8.9 14.6 6.9 5.3 12.7 10.8 10.9 5.9 355.0 10.0 33.3 18.9 12.5 11.5 42.6 63.3 75.4 60.7 49.5 57.5 64.0 63.0 54.6 46.2 63.6 50.9 430.3 41.7 18.6 55.8 69.4 29.3 23.5 22.5 37.0 31.5 86.5 37.8 17.6 15.7 28.9 27.6 18.8 10.8 77.5 20.3 99.7 18.0 242.6 114.8 46.7 205.9 19.7 86.5 33.0 20.7 10.8 34.0 35.2 240.5 34.7 104.3 286.3 11.1 51.6 37.0 54.6 14.0 61.1 127.2 48.1 740.3 26.4 115.1 35.6 62.8 76.1 31.4 34.0 23.1 44.4 41.8 15.2 17.3 269.1 39.5 9.6 24.8 69.5 17.2 39.5 36.4 36.3 45.1 42.5 25.1 30.4 13.3 51.6 64.3 11.5 39.1 SEC14L3 TAP2 ENSG00000100012 "SEC14 like lipid binding 3" Q9UDX4 22 30447959-30472017 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.8;liver: 2.9;retina: 9.0" "Group enriched" "Detected in some" 8 "Muller glia cells: 27.6;Respiratory ciliated cells: 22.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA059450 Uncertain NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: Muller glia cells - Visual perception" "HPA059450: AB_2684024" "unprognostic (2.42e-1)" "unprognostic (2.56e-1)" "unprognostic (1.42e-1)" "unprognostic (5.35e-2)" "unprognostic (2.00e-4)" "unprognostic (3.62e-3)" "unprognostic (6.68e-2)" "unprognostic (3.19e-1)" "unprognostic (2.41e-10)" "unprognostic (1.27e-1)" "unprognostic (2.09e-1)" "unprognostic (4.10e-1)" 0.0 0.1 0.2 0.1 0.1 3.8 0.0 0.3 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.2 0.0 0.0 2.9 1.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 9.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 1.7 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.3 0.2 0.0 0.2 0.0 0.2 0.0 0.1 0.4 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 2.7 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 27.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SEC31B "DKFZP434M183, SEC31B-1, SEC31L2" ENSG00000075826 "SEC31 homolog B, COPII coat complex component" Q9NQW1 10 100486646-100519864 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 28.7;Bipolar cells: 32.2;Cone photoreceptor cells: 39.6;Excitatory neurons: 38.1;Horizontal cells: 40.4;Inhibitory neurons: 40.7;Oligodendrocyte precursor cells: 32.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 9.1;JURKAT: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035882, HPA040819, HPA060052" Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 59: Non-specific - Translation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Vesicles, Cytosol" "HPA035882: AB_10795246, HPA040819: AB_10794151, HPA060052: " "unprognostic (1.23e-1)" "unprognostic (3.13e-3)" "unprognostic (3.39e-3)" "unprognostic (1.03e-2)" "unprognostic (4.85e-2)" "unprognostic (1.42e-3)" "unprognostic (1.97e-3)" "unprognostic (6.63e-2)" "unprognostic (2.22e-1)" "unprognostic (2.25e-2)" "unprognostic (1.10e-4)" "unprognostic (8.23e-3)" "prognostic unfavorable (6.41e-7)" "unprognostic (2.31e-2)" "unprognostic (2.54e-1)" "unprognostic (1.79e-1)" "unprognostic (1.01e-4)" 2.2 1.5 2.0 1.1 2.0 2.5 2.0 2.3 2.9 2.6 1.2 2.5 0.3 2.1 1.0 0.8 2.6 0.8 2.8 1.8 1.9 2.2 2.0 1.7 1.6 1.9 1.7 2.8 0.6 1.7 3.7 0.7 1.8 2.3 0.8 1.5 1.6 0.8 5.9 1.3 2.3 0.8 1.5 3.0 1.7 2.7 1.9 2.9 2.0 8.3 1.3 1.8 1.5 2.2 0.1 0.0 2.0 0.5 0.6 1.0 0.1 0.4 0.9 0.2 0.6 0.1 0.0 0.4 0.6 0.0 0.1 0.0 1.1 0.2 0.5 2.5 0.5 1.0 1.5 0.2 0.9 0.8 0.8 1.8 1.0 0.1 1.2 9.1 0.3 8.9 0.1 1.3 0.0 0.0 1.4 2.3 0.0 0.2 0.4 2.0 0.0 0.9 0.6 0.0 0.1 0.7 0.2 0.0 0.4 1.5 0.4 0.2 0.0 0.1 0.2 0.1 0.1 0.9 0.5 0.6 0.0 2.3 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.0 2.3 2.9 1.8 1.9 1.9 1.7 1.8 1.5 1.9 2.2 2.5 6.4 4.5 28.7 2.4 1.1 0.9 1.7 1.2 32.2 2.9 2.0 8.0 4.3 2.3 11.0 39.6 1.2 4.5 3.8 0.0 0.4 2.3 1.3 3.4 2.6 5.4 0.4 38.1 0.2 0.3 2.4 3.1 1.6 1.3 7.7 2.9 6.1 2.2 40.4 40.7 3.3 0.0 4.8 1.7 1.7 3.4 3.5 1.8 7.5 5.2 3.6 1.0 32.6 21.5 0.2 2.0 4.1 2.5 1.2 2.4 1.0 2.2 5.8 0.0 1.9 2.2 7.7 3.2 1.8 1.1 0.8 4.6 4.7 4.0 1.1 SEC63 "DNAJC23, ERdj2, PRO2507, SEC63L" ENSG00000025796 "SEC63 homolog, protein translocation regulator" Q9UGP8 6 107867756-107958208 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Protein transport, Transport" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Theca cells: 354.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053295, HPA060535" Supported Supported "Endoplasmic reticulum" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum" "HPA053295: AB_2682105, HPA060535: AB_2684312" "prognostic unfavorable (3.32e-4)" "prognostic unfavorable (4.01e-4)" "unprognostic (4.08e-1)" "unprognostic (1.56e-1)" "unprognostic (4.36e-3)" "unprognostic (1.51e-2)" "unprognostic (8.33e-3)" "unprognostic (1.24e-1)" "unprognostic (1.80e-1)" "unprognostic (1.04e-1)" "unprognostic (3.27e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (6.16e-4)" "unprognostic (2.35e-1)" "unprognostic (1.93e-1)" "unprognostic (1.56e-1)" "unprognostic (4.41e-2)" 27.5 33.0 11.6 22.0 14.3 32.9 23.3 14.4 12.9 30.2 25.7 19.2 16.8 25.2 29.6 19.5 21.8 22.0 19.0 12.4 15.3 20.0 46.6 21.7 16.7 13.3 12.0 40.4 61.2 31.7 14.4 20.9 14.2 27.7 18.6 21.2 77.8 23.3 14.3 15.5 18.0 22.2 12.3 16.1 23.1 33.0 12.1 22.6 52.1 14.1 17.3 21.8 14.0 17.7 28.5 17.1 46.0 57.6 47.1 55.2 41.4 59.2 65.0 27.8 39.2 30.8 34.6 52.8 49.4 53.7 34.4 40.9 32.3 38.3 42.5 63.8 35.7 57.2 25.2 31.6 73.2 65.9 32.5 43.5 61.4 44.5 97.6 50.0 39.3 31.7 48.5 82.8 57.7 22.7 20.6 29.5 36.4 30.0 18.1 65.2 54.4 43.7 33.5 37.1 40.3 45.7 32.9 48.8 59.1 31.2 34.9 95.8 42.5 41.6 25.8 42.2 46.6 31.4 25.0 52.9 45.9 56.4 48.7 5.6 5.2 5.0 4.8 4.7 7.5 4.4 3.9 3.9 5.4 4.0 4.3 3.4 1.7 7.1 9.8 6.9 2.2 3.5 11.6 14.3 14.4 12.9 12.4 15.3 13.3 12.0 14.2 12.3 12.1 17.7 55.6 118.6 143.3 38.2 64.4 85.0 70.5 90.9 42.7 57.7 67.8 54.2 78.8 81.5 125.5 53.3 39.6 80.8 71.6 39.2 11.7 86.0 40.3 48.7 102.8 61.6 53.5 31.5 52.5 125.4 96.4 107.1 46.9 54.8 68.9 84.8 59.6 126.7 62.7 47.1 50.8 80.0 83.4 56.7 78.9 23.9 106.2 54.8 80.0 42.2 54.3 61.0 59.8 60.3 64.8 81.9 53.5 118.8 144.6 91.1 37.2 38.4 116.7 49.9 46.0 108.2 77.2 143.1 75.0 44.7 80.0 91.0 52.3 354.8 60.8 73.8 SELENOP "SELP, SeP, SEPP, SEPP1" ENSG00000250722 "Selenoprotein P" P49908 5 42799880-42887392 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "intestine: 2087.6;liver: 6268.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 448.7;Alveolar cells type 2: 529.3;Granulosa cells: 458.1;Hofbauer cells: 858.5;Macrophages: 373.3;Proximal tubular cells: 1044.7" "Cancer enriched" "Detected in all" 4 "liver cancer: 116.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Hep G2: 567.4;HSkMC: 451.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036287 Approved Uncertain "Nucleoplasm,Golgi apparatus" "Secreted to blood" NA NA 2220000000 1800000000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA036287: AB_10794618" "unprognostic (7.96e-2)" "unprognostic (2.10e-1)" "unprognostic (4.28e-3)" "unprognostic (1.19e-3)" "unprognostic (6.67e-2)" "unprognostic (6.37e-2)" "unprognostic (9.22e-2)" "unprognostic (2.19e-2)" "unprognostic (1.44e-2)" "unprognostic (2.88e-1)" "unprognostic (2.07e-2)" "unprognostic (1.05e-1)" "prognostic favorable (6.97e-6)" "unprognostic (1.35e-2)" "unprognostic (4.19e-2)" "unprognostic (2.89e-1)" "unprognostic (1.42e-1)" 719.1 424.3 164.8 179.9 345.6 40.1 617.5 386.0 290.0 460.0 145.5 644.0 620.0 335.8 459.7 240.7 376.5 670.5 237.2 156.3 231.3 853.7 6268.1 512.0 552.4 519.4 316.4 701.2 229.0 246.0 108.3 973.0 490.3 214.2 714.2 59.2 170.8 374.1 156.4 171.8 2087.6 233.2 310.3 948.8 257.0 87.8 284.7 170.4 147.0 265.6 177.4 414.3 213.1 524.3 0.7 1.7 7.7 1.0 43.6 12.2 7.3 4.1 10.9 0.0 0.0 12.5 65.3 2.0 36.3 1.5 1.4 1.7 0.2 0.1 0.0 2.4 52.7 3.1 0.2 567.4 25.9 3.2 0.4 451.1 0.7 0.0 0.1 1.9 0.1 1.5 6.4 12.9 23.5 1.3 1.1 6.4 30.6 17.0 0.9 1.3 2.0 100.8 12.5 8.0 2.2 2.7 2.7 16.7 1.6 54.6 125.4 0.7 0.7 3.2 1.7 5.2 1.0 8.4 1.5 2.0 1.7 5.9 1.5 0.1 0.1 0.5 0.5 0.1 0.6 0.4 0.3 0.3 0.3 0.5 0.4 0.4 0.5 0.6 0.2 0.9 0.3 0.3 164.8 345.6 386.0 290.0 156.3 231.3 519.4 316.4 490.3 310.3 284.7 524.3 312.7 448.7 529.3 0.0 15.2 0.0 0.0 0.0 0.0 0.0 312.0 271.1 0.0 0.0 102.1 125.0 0.0 223.4 9.4 0.0 197.6 73.4 0.0 83.8 231.0 75.8 0.0 0.0 0.0 52.8 17.5 358.7 0.0 116.1 26.5 458.1 0.0 0.0 858.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 373.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 33.2 0.0 0.0 4.9 0.0 0.0 1044.7 52.5 0.0 0.0 0.0 133.1 0.0 0.0 0.0 0.0 112.9 10.0 361.8 0.0 0.0 SELL "CD62L, hLHRc, LAM-1, LAM1, Leu-8, LNHR, LSEL, Lyam-1, LYAM1, PLNHR" ENSG00000188404 "Selectin L" P14151 1 169690665-169711702 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 150.4;lymphoid tissue: 231.4" "Group enriched" "Detected in many" 5 "B-cells: 221.4;dendritic cells: 206.0;Kupffer cells: 68.9;Macrophages: 86.3;monocytes: 208.7;NK-cells: 110.2;T-cells: 104.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 11.2;JURKAT: 29.4;MOLT-4: 21.2;U-266/70: 38.8;U-698: 19.4;U-937: 11.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002144, HPA051972" Enhanced Uncertain Cytosol NA NA 4700000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "CAB002144: AB_563862, HPA051972: AB_2797242" "prognostic favorable (3.76e-4)" "prognostic favorable (2.25e-4)" "unprognostic (1.52e-2)" "unprognostic (2.89e-2)" "unprognostic (7.87e-3)" "prognostic favorable (6.43e-4)" "unprognostic (1.39e-3)" "unprognostic (3.43e-1)" "unprognostic (2.70e-3)" "prognostic favorable (3.14e-4)" "unprognostic (1.42e-1)" "unprognostic (4.21e-2)" "prognostic unfavorable (4.96e-5)" "unprognostic (4.76e-2)" "unprognostic (8.71e-3)" "unprognostic (9.57e-2)" "unprognostic (1.01e-1)" 29.3 2.3 2.8 118.8 4.5 150.4 2.6 8.4 6.2 3.7 2.7 6.8 3.2 2.6 1.7 5.5 4.7 24.1 3.1 3.2 4.0 3.0 12.1 19.4 231.4 7.4 4.5 1.0 3.7 28.0 13.9 11.2 6.1 3.7 7.1 1.0 3.8 1.9 3.4 0.6 17.0 14.5 6.4 166.8 5.6 1.1 3.9 132.2 2.8 13.6 202.0 37.9 1.4 8.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.2 0.2 0.7 0.0 0.3 11.2 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 7.7 1.3 0.5 0.0 0.0 0.0 0.0 1.8 29.4 0.1 1.4 0.0 1.8 21.2 0.3 0.1 0.4 0.3 7.8 0.2 0.7 6.1 0.3 0.0 0.0 0.0 1.4 0.0 0.8 0.0 0.0 0.0 0.6 0.2 0.0 0.0 38.8 0.0 19.4 2.0 11.1 0.3 3688.4 992.6 1696.7 284.3 211.6 78.1 613.0 528.9 294.2 756.3 734.4 1169.2 683.6 4201.4 2551.1 93.1 622.9 1011.2 2052.5 2.8 4.5 8.4 6.2 3.2 4.0 7.4 4.5 6.1 6.4 3.9 8.0 1.8 9.6 13.7 0.7 221.4 0.4 0.3 0.0 0.6 0.1 0.5 0.3 0.6 2.8 1.8 11.0 0.0 13.9 206.0 0.1 0.0 0.2 0.0 0.1 0.0 3.4 0.0 25.2 0.2 0.0 0.6 3.3 2.6 0.1 10.1 0.5 3.9 1.1 5.6 0.0 0.1 0.1 0.0 68.9 2.7 0.2 0.6 86.3 1.8 1.0 208.7 2.5 110.2 0.0 0.8 0.1 0.0 0.0 25.8 0.0 0.0 0.9 1.5 0.0 0.0 0.2 0.6 0.0 0.1 0.3 0.1 28.5 104.9 0.5 0.0 0.6 SELPLG "CD162, PSGL-1" ENSG00000110876 "Selectin P ligand" Q14242 12 108621895-108633894 "Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 86.6" "Cell type enhanced" "Detected in many" "dendritic cells: 159.7;Kupffer cells: 84.9;Macrophages: 64.8;monocytes: 123.8;NK-cells: 154.5;Plasma cells: 65.1;T-cells: 65.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 136.2;HMC-1: 130.0;JURKAT: 102.2;Karpas-707: 195.1;RPMI-8226: 286.7;U-266/70: 326.8;U-266/84: 214.5" "Low region specificity" "Detected in all" "CAB002431, HPA011256, HPA069062" Enhanced Approved Vesicles NA NA 2700000 "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "CAB002431: AB_563509, HPA011256: , HPA069062: " "unprognostic (2.32e-2)" "prognostic favorable (1.46e-4)" "unprognostic (3.64e-3)" "unprognostic (1.02e-2)" "unprognostic (6.32e-2)" "prognostic favorable (6.94e-4)" "unprognostic (2.52e-1)" "unprognostic (1.29e-1)" "prognostic favorable (2.92e-4)" "unprognostic (2.26e-1)" "unprognostic (2.12e-2)" "unprognostic (3.24e-1)" "prognostic unfavorable (5.86e-4)" "unprognostic (5.88e-2)" "unprognostic (2.37e-2)" "prognostic favorable (2.74e-4)" "unprognostic (5.44e-2)" 17.5 9.1 12.1 47.4 10.5 21.1 6.9 11.7 12.1 9.2 8.2 9.6 8.6 3.7 2.1 8.6 7.8 17.0 5.0 12.0 14.1 4.0 6.5 40.8 62.2 17.8 13.5 2.8 3.4 4.4 3.0 13.0 16.4 3.3 8.4 0.7 7.0 3.9 2.2 4.7 15.5 11.5 17.0 86.6 11.3 2.2 17.2 52.1 3.4 7.3 30.6 21.5 3.3 24.5 0.5 0.4 1.4 0.8 0.7 1.5 0.8 4.9 4.8 1.8 1.4 0.3 1.9 0.5 1.7 7.4 2.0 0.3 0.1 0.1 1.3 136.2 0.0 45.7 0.2 0.2 0.4 35.1 130.0 1.8 0.5 2.5 0.6 5.0 0.4 102.2 0.8 195.1 6.0 0.0 28.3 18.9 0.2 0.1 1.6 0.3 0.5 286.7 2.9 0.0 0.3 0.0 0.6 0.2 2.2 3.3 0.1 42.6 1.7 2.6 0.8 3.5 1.4 326.8 214.5 6.4 1.5 74.2 1.9 1543.6 297.6 940.2 419.2 509.2 344.3 22.0 396.6 362.9 299.9 22.3 300.3 323.7 1257.2 309.2 762.7 518.3 662.2 1035.5 12.1 10.5 11.7 12.1 12.0 14.1 17.8 13.5 16.4 17.0 17.2 24.5 1.2 3.2 12.4 0.0 11.6 3.4 0.1 0.2 0.0 0.2 0.6 1.4 2.2 4.3 2.7 0.0 0.0 0.5 159.7 0.2 0.0 0.3 8.2 1.8 0.6 2.6 0.0 10.9 0.2 0.2 2.3 2.4 2.6 0.9 29.7 0.4 3.6 2.2 40.1 0.0 0.3 0.0 0.0 84.9 49.6 12.2 0.3 64.8 7.2 15.9 123.8 0.0 154.5 0.0 0.1 0.5 0.0 0.0 65.1 0.1 0.0 0.5 6.4 0.2 0.0 1.2 0.9 0.8 0.5 0.5 1.8 1.0 65.9 0.1 0.0 0.0 SEMA3E "coll-5, KIAA0331, M-SemaK, SEMAH" ENSG00000170381 "Semaphorin 3E" O15041 7 83363238-83649139 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 176.3;Alveolar cells type 2: 110.2;Bipolar cells: 75.7;Excitatory neurons: 84.9;Oligodendrocyte precursor cells: 250.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 3.9;SK-BR-3: 19.9;U-2 OS: 6.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029419, HPA063804" Uncertain Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles Nucleoplasm "HPA029419: AB_10602090, HPA063804: AB_2685127" "unprognostic (4.42e-2)" "unprognostic (1.48e-2)" "unprognostic (7.82e-2)" "unprognostic (4.42e-2)" "unprognostic (2.60e-1)" "unprognostic (4.27e-2)" "unprognostic (9.36e-2)" "unprognostic (4.09e-2)" "unprognostic (3.25e-1)" "unprognostic (1.42e-1)" "unprognostic (9.09e-2)" "unprognostic (2.60e-1)" "unprognostic (1.46e-6)" "unprognostic (1.32e-2)" "unprognostic (1.14e-1)" "unprognostic (7.17e-3)" "unprognostic (2.62e-1)" 1.2 0.1 3.1 0.2 2.8 0.0 2.8 0.6 2.3 1.8 0.1 2.1 0.6 1.9 0.3 1.2 0.6 2.3 0.1 5.0 5.3 0.1 0.1 2.2 0.0 1.6 4.3 0.1 0.4 0.0 0.2 0.2 1.3 4.3 1.7 3.9 2.2 3.3 0.2 0.5 1.2 1.1 3.2 0.0 1.3 0.0 4.3 1.7 0.6 1.0 0.1 3.2 0.7 3.7 0.2 1.1 0.2 0.0 0.5 3.1 0.0 0.0 0.2 0.2 0.3 0.0 0.3 0.0 0.0 0.0 0.5 0.0 3.4 0.0 1.3 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.9 0.0 0.0 0.5 0.4 1.1 0.0 2.0 0.0 0.0 0.8 0.1 0.0 0.0 19.9 0.0 3.2 1.6 0.0 0.0 0.7 6.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 2.8 0.6 2.3 5.0 5.3 1.6 4.3 1.3 3.2 4.3 3.7 10.5 176.3 110.2 2.9 0.2 1.1 1.3 1.6 0.0 75.7 19.0 7.5 1.7 18.6 43.2 1.8 0.0 0.8 0.2 0.1 0.0 3.9 1.1 3.8 1.2 10.7 0.0 0.0 84.9 1.1 0.4 21.3 3.1 9.3 24.0 0.2 0.0 0.3 0.1 0.0 12.3 0.0 4.1 1.0 2.1 0.0 0.9 3.6 1.8 1.0 1.0 29.6 0.0 250.3 6.0 6.2 0.0 0.0 0.3 2.6 0.1 0.5 35.7 3.6 0.0 0.8 1.0 0.3 0.6 0.3 0.4 0.3 2.8 0.0 0.0 2.5 SEMA5B "FLJ10372, KIAA1445, SEMAG, SemG" ENSG00000082684 "Semaphorin 5B" Q9P283 3 122909082-123028605 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.2" "Cell type enhanced" "Detected in some" "Astrocytes: 9.4;Excitatory neurons: 30.8;Muller glia cells: 7.3;Oligodendrocyte precursor cells: 45.2;Smooth muscle cells: 14.3" "Cancer enhanced" "Detected in many" "renal cancer: 18.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 79.7;NTERA-2: 15.7;SH-SY5Y: 21.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066548 Enhanced Supported Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA066548: AB_2685689" "unprognostic (7.34e-2)" "unprognostic (1.84e-3)" "unprognostic (1.92e-4)" "unprognostic (3.01e-2)" "unprognostic (1.04e-1)" "unprognostic (2.28e-1)" "unprognostic (4.72e-2)" "unprognostic (1.58e-2)" "unprognostic (7.66e-3)" "unprognostic (2.87e-2)" "unprognostic (4.71e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (7.57e-4)" "unprognostic (1.31e-3)" "unprognostic (5.96e-2)" "unprognostic (6.12e-2)" "unprognostic (2.12e-1)" 1.7 1.5 12.1 0.4 11.8 0.0 1.3 7.3 15.9 1.8 6.7 1.3 0.9 1.4 2.8 0.7 3.5 2.5 9.5 16.2 8.0 9.1 0.9 1.2 0.6 8.4 8.5 1.4 1.7 0.6 2.7 2.6 9.7 1.4 0.8 7.1 0.4 1.4 0.9 1.5 1.5 1.9 7.7 0.2 0.6 0.7 7.8 0.2 2.6 0.5 0.6 1.6 1.6 10.9 0.0 0.0 79.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.3 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 15.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 21.3 0.0 0.2 0.0 3.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 11.8 7.3 15.9 16.2 8.0 8.4 8.5 9.7 7.7 7.8 10.9 1.2 0.0 1.1 9.4 0.0 0.0 0.0 0.1 0.0 7.2 0.1 0.0 3.5 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.8 0.0 0.0 30.8 0.0 0.3 0.7 0.0 0.0 0.0 0.1 1.8 0.0 0.1 0.0 6.6 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.9 0.6 7.3 0.0 45.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.1 14.3 0.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 SEMA6A "HT018, KIAA1368, SEMA, SEMA6A1, SEMAQ" ENSG00000092421 "Semaphorin 6A" Q9H2E6 5 116443555-116574823 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 60.1;brain: 75.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 128.9;Hepatic stellate cells: 145.6;Horizontal cells: 138.0;Oligodendrocyte precursor cells: 138.7;Oligodendrocytes: 311.3;Syncytiotrophoblasts: 348.1" "Cancer enhanced" "Detected in all" "testis cancer: 20.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 44.3;HAP1: 52.0;NTERA-2: 115.2;SuSa: 221.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031264, HPA031265, HPA031267" Approved Approved "Nucleoplasm,Nuclear bodies,Intermediate filaments" NA NA 620000 "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Nuclear bodies, Intermediate filaments" "HPA031264: , HPA031265: AB_10610423, HPA031267: " "unprognostic (3.79e-2)" "unprognostic (3.91e-1)" "unprognostic (1.82e-2)" "unprognostic (6.81e-2)" "unprognostic (2.69e-2)" "unprognostic (3.77e-1)" "prognostic unfavorable (4.39e-4)" "unprognostic (1.64e-1)" "unprognostic (4.71e-2)" "unprognostic (5.82e-2)" "unprognostic (1.92e-2)" "unprognostic (1.13e-1)" "unprognostic (2.24e-1)" "unprognostic (3.62e-3)" "unprognostic (1.92e-1)" "unprognostic (6.21e-3)" "unprognostic (7.32e-3)" 13.4 60.1 24.1 4.9 48.6 3.5 13.1 39.9 31.9 10.0 0.3 20.6 19.9 6.0 2.8 4.4 8.2 12.9 7.1 24.5 40.3 8.6 5.6 17.9 4.5 51.9 41.0 18.1 11.2 2.0 5.8 31.9 50.0 6.0 17.5 10.4 16.6 2.5 8.2 6.9 25.5 5.8 32.9 11.2 7.0 7.5 44.1 3.6 9.1 6.5 2.2 5.6 8.1 75.2 0.3 0.1 36.9 44.3 0.2 0.0 38.2 0.7 0.4 0.2 0.2 2.2 1.5 1.6 1.7 0.6 0.7 0.4 52.0 0.0 0.1 1.6 7.7 0.7 0.7 13.1 0.5 0.5 2.6 0.7 0.0 0.0 0.0 0.5 0.2 0.3 0.3 0.4 0.2 0.8 0.7 3.9 115.2 0.2 0.3 6.9 24.2 1.8 19.0 33.7 10.3 3.7 0.2 0.7 19.7 221.1 14.4 2.6 0.9 3.6 3.1 0.4 1.5 0.6 0.7 0.8 0.6 1.8 13.8 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 24.1 48.6 39.9 31.9 24.5 40.3 51.9 41.0 50.0 32.9 44.1 75.2 64.7 0.0 0.6 71.8 1.1 6.5 0.7 13.1 34.7 17.9 17.0 8.3 8.6 61.5 3.1 14.7 2.1 128.9 0.3 73.3 0.0 42.9 13.6 12.2 4.8 60.9 28.1 2.7 26.9 1.3 8.1 15.4 1.1 10.6 0.0 9.7 145.6 0.9 12.5 138.0 62.2 30.7 0.0 14.8 4.6 2.4 6.5 1.1 24.9 54.4 0.1 5.8 0.0 138.7 311.3 2.0 46.7 1.9 2.6 1.5 40.7 4.4 0.6 3.5 0.0 36.1 8.1 0.9 1.5 11.3 4.1 348.1 0.8 3.5 40.3 2.2 SEMA6B "SEM-SEMA-Y, SEMA-VIB, SEMAN, semaZ" ENSG00000167680 "Semaphorin 6B" Q9H3T3 19 4542593-4581776 "Disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.3" "Cell type enhanced" "Detected in many" "Adipocytes: 43.6;Alveolar cells type 1: 28.9;Alveolar cells type 2: 44.6;Endothelial cells: 40.1;Excitatory neurons: 30.6;granulocytes: 29.7;Hepatic stellate cells: 37.5;Inhibitory neurons: 30.3;Macrophages: 35.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 124.5;HMC-1: 198.1;HUVEC TERT2: 83.8;TIME: 107.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025157, HPA055778, HPA058523" Enhanced NA NA 1100000 "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "CAB025157: , HPA055778: AB_2682916, HPA058523: AB_2683741" "unprognostic (4.03e-1)" "unprognostic (9.69e-3)" "unprognostic (6.38e-3)" "unprognostic (2.15e-1)" "unprognostic (1.15e-1)" "unprognostic (7.94e-2)" "unprognostic (2.10e-1)" "unprognostic (4.34e-3)" "unprognostic (6.61e-2)" "unprognostic (1.90e-1)" "unprognostic (4.21e-2)" "unprognostic (2.82e-1)" "prognostic unfavorable (3.29e-5)" "unprognostic (1.26e-1)" "unprognostic (1.81e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (9.55e-2)" 25.6 19.7 44.0 11.0 30.7 7.8 17.1 0.6 72.3 8.7 0.0 6.6 4.0 10.6 0.4 3.6 8.8 5.8 20.2 65.2 12.4 13.3 2.9 10.7 1.2 13.5 11.0 3.3 4.1 9.2 7.2 8.9 1.8 7.0 1.0 1.4 3.9 1.3 6.0 4.6 7.3 6.9 0.5 31.9 6.1 1.9 30.2 0.7 9.1 4.3 0.7 10.0 6.7 17.4 7.2 25.0 2.3 21.4 0.1 1.2 0.2 0.0 0.7 2.4 0.6 0.2 2.0 0.0 23.7 0.0 3.8 4.4 6.5 0.0 0.9 0.1 1.0 0.0 0.4 124.5 0.4 0.0 198.1 7.5 0.1 0.2 0.2 24.9 83.8 0.1 1.6 0.3 0.7 6.5 0.0 0.0 26.8 1.7 0.3 0.4 46.8 0.6 1.7 0.1 17.7 1.7 0.1 1.7 11.5 1.8 2.7 1.1 107.8 3.1 34.7 0.5 18.6 1.3 0.0 0.4 0.8 1.3 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.0 30.7 0.6 72.3 65.2 12.4 13.5 11.0 1.8 0.5 30.2 17.4 43.6 28.9 44.6 2.6 2.3 4.7 1.5 0.5 0.0 9.0 2.1 1.9 1.9 1.5 19.3 1.8 4.2 0.6 2.3 0.2 0.0 1.1 1.1 1.1 2.5 40.1 0.0 8.4 30.6 0.2 0.6 8.2 0.0 2.0 29.7 0.5 37.5 6.0 3.3 18.5 30.3 0.1 0.0 6.1 18.1 0.4 0.6 35.2 7.2 7.5 1.4 2.0 1.0 19.1 1.4 0.2 0.1 0.7 1.1 1.2 0.0 0.4 17.7 4.1 0.0 8.8 1.8 2.0 2.2 0.0 5.1 0.3 5.4 1.6 0.1 0.9 SEMA6C KIAA1869 ENSG00000143434 "Semaphorin 6C" Q9H3T2 1 151131685-151146664 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 322.9;tongue: 96.9" "Cell type enhanced" "Detected in many" "Adipocytes: 12.9;Cardiomyocytes: 19.1;Cone photoreceptor cells: 20.9;Inhibitory neurons: 13.7;Skeletal myocytes: 12.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 14.1;HUVEC TERT2: 24.8;TIME: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA076150, HPA077625" Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 1500000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Plasma membrane" "Nucleoli fibrillar center, Cytosol" "HPA076150: , HPA077625: " "unprognostic (6.97e-2)" "unprognostic (8.40e-2)" "unprognostic (1.56e-3)" "prognostic unfavorable (3.27e-4)" "unprognostic (2.79e-1)" "unprognostic (2.88e-2)" "unprognostic (3.00e-2)" "unprognostic (1.24e-2)" "unprognostic (5.66e-3)" "unprognostic (4.25e-2)" "prognostic favorable (3.06e-5)" "unprognostic (3.72e-2)" "unprognostic (1.67e-2)" "unprognostic (6.12e-2)" "unprognostic (9.49e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" 8.8 2.8 7.7 1.8 6.7 1.2 7.9 21.9 9.4 12.0 1.0 7.6 13.7 10.5 1.4 5.5 10.7 3.7 38.8 7.9 5.4 12.1 12.4 5.1 1.7 5.0 5.0 14.8 3.6 2.1 13.4 1.9 4.9 8.3 1.8 5.2 8.5 2.3 322.9 8.9 10.8 6.2 2.2 3.0 5.4 32.2 7.3 2.2 4.7 96.9 0.9 8.4 8.8 5.3 0.9 1.0 14.1 5.4 5.8 1.9 1.3 1.0 0.5 0.9 1.3 0.3 0.6 0.7 4.0 3.3 2.0 1.4 1.3 0.5 0.8 1.3 4.2 7.7 0.7 1.2 0.8 0.1 2.7 3.3 1.7 1.2 0.6 2.8 24.8 4.1 0.7 0.7 2.3 0.5 1.3 1.0 6.3 0.2 1.7 9.0 3.1 0.3 0.5 0.4 7.1 9.3 1.3 0.6 1.2 3.5 1.6 1.3 11.8 2.3 3.3 3.5 0.6 5.9 1.2 6.1 0.6 0.3 0.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 6.7 21.9 9.4 7.9 5.4 5.0 5.0 4.9 2.2 7.3 5.3 12.9 0.0 2.8 3.9 1.0 1.7 0.8 0.3 0.6 5.7 1.9 3.0 19.1 1.5 0.8 0.0 20.9 0.2 0.6 0.1 0.0 0.3 0.6 0.4 2.8 10.2 0.0 0.8 6.7 0.4 0.6 4.4 0.5 0.4 0.0 9.9 6.8 5.3 0.4 6.7 13.7 0.3 0.0 2.5 0.7 3.1 5.6 0.5 1.8 4.7 0.4 1.9 1.0 5.5 1.5 0.4 0.0 2.6 1.9 0.5 3.3 2.9 0.3 7.5 0.0 12.0 2.9 3.3 1.2 0.5 1.0 0.1 0.8 0.5 0.8 0.5 SEMA6D "FLJ11598, KIAA1479" ENSG00000137872 "Semaphorin 6D" Q8NFY4 15 47184101-47774228 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.5;placenta: 43.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 114.7;Excitatory neurons: 120.7;Horizontal cells: 79.1;Inhibitory neurons: 319.5;Oligodendrocytes: 140.1" "Cancer enriched" "Detected in many" 4 "glioma: 8.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 14.9;SCLC-21H: 13.3;SH-SY5Y: 12.1;SuSa: 14.2;U-266/70: 10.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043109 Approved "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA 1100000 "Cluster 45: Intestine - Brush border" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Golgi apparatus" "HPA043109: AB_10793941" "unprognostic (2.00e-1)" "unprognostic (4.62e-2)" "unprognostic (3.10e-2)" "unprognostic (3.83e-3)" "unprognostic (1.38e-1)" "unprognostic (3.85e-2)" "unprognostic (1.98e-1)" "unprognostic (2.17e-3)" "unprognostic (1.24e-1)" "unprognostic (5.36e-2)" "unprognostic (7.96e-4)" "unprognostic (1.42e-1)" "prognostic favorable (5.96e-5)" "unprognostic (3.74e-2)" "unprognostic (8.56e-2)" "unprognostic (3.30e-3)" "unprognostic (2.39e-4)" 5.5 1.5 11.3 3.9 27.9 0.4 5.0 11.1 21.3 5.8 0.0 10.6 21.8 1.6 2.5 1.7 4.9 4.0 9.4 9.8 16.3 15.1 3.1 8.9 2.1 17.2 31.1 26.7 16.1 10.6 5.5 43.1 23.1 4.5 12.7 15.8 4.5 8.4 20.9 3.0 38.5 3.3 12.0 2.5 3.0 2.6 20.5 2.7 5.8 6.0 0.6 3.1 10.0 28.8 0.0 0.0 2.5 0.0 1.5 1.2 0.2 0.6 14.9 0.4 0.0 0.3 0.1 2.2 0.0 4.0 0.0 7.6 3.4 1.1 0.1 1.1 1.7 0.0 5.0 0.0 4.0 0.0 0.2 1.1 8.3 0.0 0.5 0.0 1.0 5.7 0.1 3.4 0.4 0.8 2.8 0.7 4.6 0.0 0.0 1.6 0.1 2.4 1.1 1.1 13.3 12.1 0.1 1.0 4.3 14.2 0.5 0.0 0.0 6.9 0.3 0.2 0.0 10.0 0.0 2.3 1.8 0.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 11.3 27.9 11.1 21.3 9.8 16.3 17.2 31.1 23.1 12.0 20.5 28.8 13.9 51.3 1.5 72.8 0.2 2.0 4.0 1.4 1.2 6.2 0.5 10.7 10.0 4.3 2.1 11.0 114.7 19.7 0.1 40.6 5.9 1.0 0.2 0.5 2.3 10.1 17.4 0.0 120.7 0.2 1.8 10.8 0.0 0.3 3.8 71.0 5.0 0.9 2.6 79.1 319.5 5.4 0.0 0.0 1.9 1.2 23.3 1.0 8.8 15.9 0.0 9.3 0.0 43.2 140.1 0.3 8.5 13.5 0.0 1.2 53.5 0.2 0.1 2.3 0.0 9.3 13.9 0.8 6.3 0.3 1.1 4.7 0.2 3.4 15.1 1.6 SEPHS1 "SPS, SPS1" ENSG00000086475 "Selenophosphate synthetase 1" P49903 10 13317428-13348298 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037645, HPA062118" Enhanced Uncertain Nucleoplasm NA NA 21000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA037645: AB_10671631, HPA062118: AB_2732676" "unprognostic (8.18e-3)" "unprognostic (1.79e-1)" "unprognostic (1.06e-3)" "unprognostic (2.07e-1)" "unprognostic (3.50e-2)" "unprognostic (2.99e-2)" "prognostic unfavorable (2.16e-7)" "unprognostic (2.66e-2)" "unprognostic (1.43e-1)" "unprognostic (2.61e-2)" "prognostic favorable (3.12e-4)" "unprognostic (1.09e-1)" "unprognostic (1.38e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" "unprognostic (1.66e-1)" "unprognostic (5.11e-2)" 27.8 28.6 23.2 23.6 23.9 25.3 33.5 25.3 22.3 25.6 28.1 31.2 23.2 32.3 35.9 24.6 35.3 23.8 30.8 21.7 24.1 56.5 48.6 24.3 29.3 26.7 28.4 35.7 33.6 48.1 23.5 27.8 23.1 26.4 32.7 25.0 26.9 24.7 33.3 20.9 24.6 33.2 25.9 21.8 25.6 22.1 24.6 64.3 55.4 36.6 34.3 24.8 17.4 24.4 127.7 90.8 182.4 176.3 59.4 45.1 85.8 55.4 42.6 115.6 97.9 103.5 116.4 123.1 67.2 65.0 55.9 79.6 195.2 91.4 120.5 186.7 80.9 67.4 66.8 132.9 61.4 92.0 41.4 39.6 64.6 67.7 39.5 53.9 95.0 255.9 90.7 97.5 83.2 168.1 228.8 39.3 301.8 119.8 40.9 176.3 88.8 73.7 62.2 51.0 64.5 119.5 169.6 74.1 75.7 157.7 93.8 96.1 64.1 51.1 96.3 67.6 117.6 71.3 143.4 228.1 41.2 67.6 41.9 10.2 11.6 8.8 7.7 17.1 9.5 9.5 7.8 8.9 13.6 6.4 10.0 9.4 1.7 15.4 24.8 15.4 13.3 8.3 23.2 23.9 25.3 22.3 21.7 24.1 26.7 28.4 23.1 25.9 24.6 24.4 24.1 12.8 13.1 8.1 12.3 17.2 16.5 19.3 9.6 17.1 23.8 19.4 14.1 20.0 18.0 22.0 0.0 31.6 27.1 17.6 33.2 26.4 13.5 16.9 15.4 26.1 16.7 19.3 8.2 30.1 45.2 18.0 11.7 16.1 15.8 27.7 19.6 32.7 21.1 21.9 8.3 13.7 20.3 10.1 11.7 14.1 14.9 13.1 16.0 4.7 8.0 35.2 9.2 4.0 12.9 34.1 15.3 18.4 18.7 17.5 16.4 44.6 13.4 15.6 6.6 14.2 26.1 17.6 21.2 15.0 16.9 25.6 13.2 25.9 18.0 15.1 SERINC1 "KIAA1253, TDE1L, TDE2, TMS-2" ENSG00000111897 "Serine incorporator 1" Q9NRX5 6 122443351-122471807 "Plasma proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035738, HPA035739" Uncertain Approved Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA035738: AB_10672990, HPA035739: AB_10669536" "unprognostic (2.83e-3)" "unprognostic (2.68e-3)" "unprognostic (1.59e-1)" "unprognostic (7.67e-2)" "unprognostic (2.65e-1)" "unprognostic (2.84e-2)" "unprognostic (2.04e-1)" "unprognostic (7.45e-2)" "unprognostic (9.84e-2)" "unprognostic (8.27e-2)" "unprognostic (9.07e-3)" "unprognostic (2.84e-1)" "unprognostic (5.50e-3)" "unprognostic (1.80e-3)" "unprognostic (9.22e-2)" "unprognostic (3.58e-1)" "unprognostic (1.00e-2)" 213.6 242.8 220.4 93.2 248.8 148.2 157.8 237.5 334.0 151.4 178.5 104.6 99.4 146.6 108.1 94.9 104.4 128.0 163.7 248.3 257.3 194.1 241.3 160.5 96.8 258.9 243.3 164.4 100.4 243.3 71.7 195.1 282.9 139.6 100.1 225.5 97.1 143.3 152.6 79.0 114.3 141.7 268.4 123.6 96.5 65.6 241.3 89.7 203.1 194.8 79.5 121.7 84.8 306.8 40.5 49.1 121.7 111.8 450.2 245.1 64.5 208.4 259.8 111.6 171.6 57.8 106.9 27.1 159.7 236.5 127.9 78.7 72.6 90.2 166.1 87.1 86.0 76.9 79.0 105.9 201.3 77.5 146.3 256.7 173.0 139.0 190.8 256.4 98.1 69.9 77.4 149.3 233.8 46.8 35.1 51.4 39.7 63.5 61.9 42.5 60.0 66.5 240.3 70.1 63.6 114.5 92.3 101.2 146.8 107.4 70.0 107.1 201.3 133.7 57.9 110.8 109.9 112.4 134.4 35.9 176.8 62.1 159.5 158.3 43.0 92.6 44.7 53.2 48.1 27.7 45.9 43.3 35.9 23.7 53.2 46.9 108.7 51.7 62.0 28.0 54.2 56.0 220.4 248.8 237.5 334.0 248.3 257.3 258.9 243.3 282.9 268.4 241.3 306.8 167.8 150.6 99.2 44.4 73.9 66.2 81.1 55.7 61.5 114.4 71.7 57.1 156.2 87.2 58.9 77.3 70.9 53.8 80.9 88.8 9.8 63.0 3.2 54.9 103.3 130.0 84.5 81.5 92.5 48.7 57.7 131.4 39.8 106.8 124.0 58.1 127.8 132.1 73.1 138.0 145.7 41.8 36.7 158.2 86.4 10.0 126.8 107.4 94.3 65.6 58.1 97.2 58.7 48.2 134.0 78.4 43.6 131.3 80.0 86.1 80.1 44.0 56.1 70.6 59.2 105.1 110.6 25.7 17.0 39.0 74.9 119.7 100.7 99.8 32.7 97.1 SERPINA1 "A1A, A1AT, AAT, alpha-1-antitrypsin, alpha1AT, PI, PI1" ENSG00000197249 "Serpin family A member 1" P01009 14 94376747-94390693 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 45 "liver: 34022.4" "Cell type enriched" "Detected in many" 8 "Hepatocytes: 42919.3" "Cancer enriched" "Detected in all" 10 "liver cancer: 3850.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 2482.1;intermediate monocyte: 3411.9;neutrophil: 2823.2;non-classical monocyte: 4518.8" "Group enriched" "Detected in all" 5 "granulocytes: 2823.2;monocytes: 4518.8" "Cell line enriched" "Detected in many" 10 "Hep G2: 4769.1" "Not detected" "Not detected" "Region enriched" "Detected in many" 6 "cerebellum: 130.6" "HPA000927, HPA001292, CAB013211, CAB016648, CAB073396" Enhanced Enhanced Vesicles "Secreted to blood" NA NA 2070000000000 140000000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB013211: , CAB016648: AB_1611888, CAB073396: , HPA000927: AB_1844761, HPA001292: AB_1844762" "prognostic favorable (1.61e-5)" "unprognostic (3.37e-1)" "prognostic favorable (5.86e-4)" "unprognostic (1.38e-2)" "unprognostic (1.98e-2)" "unprognostic (5.50e-3)" "unprognostic (3.81e-2)" "unprognostic (6.78e-2)" "unprognostic (2.54e-2)" "unprognostic (7.96e-2)" "unprognostic (1.08e-1)" "unprognostic (4.54e-1)" "unprognostic (1.23e-2)" "unprognostic (1.89e-1)" "unprognostic (1.30e-2)" "unprognostic (1.17e-2)" "unprognostic (1.96e-1)" 49.1 9.7 7.3 225.0 7.1 157.1 100.6 9.1 21.3 105.7 11.1 151.0 278.6 42.3 5.3 10.1 22.4 352.3 12.5 7.3 11.1 621.2 34022.4 570.7 37.0 20.9 14.4 5.4 201.0 5.2 9.1 26.6 15.8 12.6 178.8 2.6 33.6 140.5 3.7 8.2 760.9 75.7 12.2 313.6 282.5 3.0 16.2 15.0 23.0 11.9 25.2 55.8 9.1 16.9 25.9 0.3 0.0 0.5 1.0 0.0 1.5 0.6 1.7 0.6 1.1 187.8 500.8 2.6 15.6 0.0 1.4 1.9 0.0 10.9 1.2 70.1 0.0 4.3 2.0 4769.1 0.3 16.8 2.3 4.1 5.4 0.3 18.5 1.9 0.0 0.0 3.2 0.4 0.0 0.8 1.1 12.1 2.0 5.5 8.0 1.9 16.7 2.4 300.8 3.0 0.6 1.3 6.4 1.6 1.4 0.4 262.1 2.7 1.6 2.1 59.4 1.9 7.1 3.3 1.8 7.0 4.4 41.8 0.6 10.6 2482.1 634.3 5.5 3411.9 6.8 7.7 3.6 4.1 683.6 3.6 4.3 3.6 2823.2 5.3 4518.8 14.9 4.5 2770.7 7.3 7.1 9.1 21.3 7.3 11.1 20.9 14.4 15.8 12.2 16.2 16.9 2.2 35.3 285.9 0.0 137.4 2.3 1.0 36.3 0.0 0.2 100.8 31.5 5.3 4520.9 165.5 150.8 0.0 1.6 3.9 52.0 68.4 3787.9 0.2 70.0 2.8 57.0 12.1 1227.4 0.0 225.8 4.5 3.6 36.2 51.3 1.3 0.1 938.8 42919.3 167.6 0.0 0.0 742.4 30.5 1454.0 74.1 1.1 0.0 413.3 1.8 1.0 291.7 0.3 9.2 0.0 0.0 2161.6 137.0 0.0 1.5 6.8 5270.0 745.9 108.3 0.2 0.0 0.6 17.4 0.0 0.2 0.6 1.7 6.4 75.5 0.0 83.2 6.7 SERPINA10 "PZI, ZPI" ENSG00000140093 "Serpin family A member 10" Q9UK55 14 94280460-94293268 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 104 "liver: 346.9" "Cell type enriched" "Detected in some" 17 "Hepatocytes: 259.1" "Cancer enriched" "Detected in some" 51 "liver cancer: 40.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "Hep G2: 21.2" "Not detected" "Not detected" HPA048739 Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 3960000000 4700000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Nucleoplasm Cytosol "HPA048739: AB_2797237" "unprognostic (7.14e-2)" "unprognostic (2.03e-1)" "unprognostic (2.69e-2)" "unprognostic (2.01e-1)" "unprognostic (1.21e-1)" "unprognostic (1.45e-1)" "prognostic favorable (9.00e-4)" "unprognostic (6.11e-2)" "unprognostic (2.81e-4)" "unprognostic (2.31e-4)" "unprognostic (2.77e-2)" "unprognostic (2.91e-3)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (1.11e-1)" "unprognostic (7.93e-3)" 0.4 0.4 0.4 0.6 0.7 3.3 0.6 3.2 1.4 0.6 0.4 0.7 0.7 0.7 0.5 0.4 0.3 0.5 0.6 0.4 0.4 0.5 346.9 0.4 0.8 1.5 0.5 0.9 0.5 0.2 0.2 0.5 0.8 0.4 0.7 3.1 0.4 0.4 0.5 1.7 0.7 0.6 0.4 0.7 0.7 0.6 0.7 1.3 0.7 0.4 0.4 0.2 0.1 2.5 0.6 0.2 1.8 0.7 0.7 0.6 0.4 0.5 0.5 0.9 0.8 2.7 0.6 2.1 0.3 0.4 0.2 0.4 2.2 0.5 1.3 0.8 1.4 2.0 0.8 21.2 0.4 1.6 1.1 0.6 0.5 0.3 0.7 1.1 1.0 1.1 0.5 1.3 1.0 0.3 1.4 0.8 0.8 0.2 0.6 0.9 1.2 0.9 0.5 0.7 0.9 0.8 0.4 0.4 0.2 1.0 0.9 0.9 0.6 0.7 0.4 0.7 0.6 1.1 0.5 0.9 0.9 1.9 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 3.2 1.4 0.4 0.4 1.5 0.5 0.8 0.4 0.7 2.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.8 2.8 0.0 0.0 14.6 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.1 6.6 8.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 3.3 259.1 0.0 0.0 0.0 0.4 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 SERPINB6 "CAP, DFNB91, PI6, PTI" ENSG00000124570 "Serpin family B member 6" P35237 6 2948159-2972165 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 563.0;Late spermatids: 1154.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA009668, HPA012736" Enhanced Approved Centrosome NA NA 4800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" Centrosome "HPA009668: AB_1079919, HPA012736: AB_1856729" "unprognostic (3.44e-1)" "unprognostic (1.03e-1)" "unprognostic (8.72e-2)" "unprognostic (1.96e-3)" "unprognostic (2.72e-2)" "unprognostic (1.56e-2)" "unprognostic (1.66e-3)" "unprognostic (1.96e-2)" "unprognostic (7.63e-2)" "prognostic favorable (4.81e-4)" "unprognostic (3.51e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (1.59e-1)" "unprognostic (5.08e-2)" "unprognostic (1.80e-1)" "unprognostic (1.10e-2)" 122.7 170.7 101.1 66.9 108.4 66.6 107.9 103.6 134.3 135.9 103.8 133.7 191.2 95.9 82.2 131.5 118.9 77.7 243.9 98.6 104.2 136.7 63.3 151.7 52.7 111.7 107.1 169.7 282.5 94.4 92.0 133.5 110.6 160.4 103.3 56.4 92.5 95.6 232.0 50.9 210.3 89.4 105.8 164.5 115.0 203.8 106.7 26.7 101.3 266.8 47.2 107.7 95.5 115.4 156.2 99.6 32.2 134.3 85.6 189.2 99.2 142.1 170.7 109.9 127.3 35.0 108.5 0.8 161.6 161.7 124.8 228.8 90.3 144.1 102.2 204.9 41.2 90.7 111.8 60.0 148.5 1.1 53.0 109.4 98.5 104.8 26.9 191.1 263.7 0.5 118.7 2.0 198.0 110.7 0.5 1.5 19.1 175.5 188.8 10.1 59.3 130.7 138.7 37.1 1.5 82.5 116.9 17.3 162.4 118.6 75.3 73.8 188.7 111.1 41.4 252.0 97.1 3.0 0.6 2.7 85.4 90.8 117.8 60.6 104.9 121.2 51.5 107.6 25.7 27.3 28.9 35.5 103.6 22.9 33.7 56.1 8.6 86.0 90.7 10.3 5.0 91.1 101.1 108.4 103.6 134.3 98.6 104.2 111.7 107.1 110.6 105.8 106.7 115.4 127.8 51.3 69.6 34.3 33.0 20.5 68.4 141.8 23.9 28.4 62.4 63.0 142.6 42.9 141.6 75.4 20.9 146.4 56.8 237.9 99.7 194.6 563.0 89.4 91.4 137.5 73.0 29.9 14.2 338.3 346.6 84.9 108.6 47.8 104.5 83.5 232.7 31.9 182.3 30.3 21.5 169.7 114.0 181.9 70.2 1154.3 83.3 124.2 64.0 92.8 151.8 172.4 46.4 31.7 56.2 318.5 237.0 85.0 17.4 99.3 418.3 216.4 174.2 50.4 78.9 119.7 104.6 233.2 33.1 34.0 26.3 161.4 42.2 65.0 206.5 94.9 SERPING1 "C1-INH, C1IN, C1INH, C1NH, HAE1, HAE2" ENSG00000149131 "Serpin family G member 1" P05155 11 57597387-57619171 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Complement pathway, Fibrinolysis, Hemostasis, Immunity, Innate immunity" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 2622.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 726.4;Ductal cells: 604.0;Fibroblasts: 793.6;Hepatocytes: 2530.0;Leydig cells: 735.3" "Cancer enhanced" "Detected in all" "liver cancer: 609.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 65.2;plasmacytoid DC: 60.6" "Group enriched" "Detected in many" 243 "dendritic cells: 60.6;granulocytes: 65.2;monocytes: 25.7" "Group enriched" "Detected in many" 6 "ASC diff: 1372.2;ASC TERT1: 694.9;HSkMC: 1159.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 194.1" "CAB026161, HPA048738" Supported "Secreted to blood" NA NA 28000000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "CAB026161: , HPA048738: AB_2680505" "unprognostic (1.35e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (9.96e-4)" "unprognostic (4.26e-2)" "unprognostic (4.38e-2)" "unprognostic (2.32e-1)" "unprognostic (4.12e-3)" "unprognostic (2.13e-1)" "unprognostic (8.95e-2)" "prognostic favorable (8.03e-4)" "unprognostic (5.92e-3)" "unprognostic (3.76e-2)" "prognostic unfavorable (1.55e-4)" "unprognostic (2.60e-2)" "unprognostic (4.14e-2)" "unprognostic (2.56e-1)" "unprognostic (1.17e-1)" 971.5 144.2 27.4 90.0 27.5 10.9 733.0 27.1 36.0 629.4 53.4 358.7 52.0 616.7 163.3 162.0 793.2 533.0 547.1 26.2 34.8 337.3 2622.4 785.0 147.6 67.4 34.7 918.3 267.5 55.2 138.2 198.9 34.2 329.3 97.0 34.5 250.5 258.1 151.8 293.5 283.5 226.8 42.3 240.7 344.8 50.6 37.2 36.1 338.2 173.4 64.4 555.9 519.8 35.1 0.0 0.0 48.2 0.0 1372.2 694.9 7.3 74.2 57.0 16.8 30.7 2.5 0.0 0.0 96.7 42.1 0.0 0.0 0.4 4.7 9.4 0.0 0.1 33.7 0.0 1.7 170.3 0.9 5.4 1159.0 15.5 5.7 0.2 6.0 0.0 0.0 1.0 0.0 1.0 0.0 0.0 1.3 46.6 0.0 0.0 4.3 4.0 0.7 7.4 0.0 0.2 14.4 0.3 0.0 0.9 41.8 0.2 3.3 0.0 0.8 21.2 0.7 0.0 0.2 0.4 0.6 0.2 0.5 0.0 0.0 18.3 0.3 0.0 25.7 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 65.2 0.2 11.5 60.6 0.0 5.7 27.4 27.5 27.1 36.0 26.2 34.8 67.4 34.7 34.2 42.3 37.2 35.1 162.1 118.6 110.8 5.5 8.0 75.8 61.2 7.1 24.5 0.8 24.2 57.7 28.7 726.4 57.5 158.2 0.0 37.1 15.3 0.0 43.0 604.0 4.8 76.0 297.4 150.5 0.0 69.2 3.6 44.0 93.4 793.6 8.6 69.6 7.6 8.3 260.5 2530.0 43.6 0.0 6.2 0.1 2.0 118.9 94.2 25.6 735.3 46.9 90.7 15.9 10.4 57.2 0.0 3.5 0.5 41.4 0.0 228.7 4.5 32.4 0.0 53.5 23.1 4.5 269.5 143.6 259.6 2.5 10.4 9.0 59.5 25.2 16.8 3.4 0.0 37.4 SEZ6L2 "FLJ90517, PSK-1" ENSG00000174938 "Seizure related 6 homolog like 2" Q6UXD5 16 29871159-29899547 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 101.6;pituitary gland: 91.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 236.6;Cone photoreceptor cells: 185.6;Enteroendocrine cells: 132.5;Horizontal cells: 188.4;Rod photoreceptor cells: 230.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 76.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064471 Enhanced NA NA 5600000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" "HPA064471: AB_2685271" "unprognostic (2.56e-2)" "prognostic unfavorable (7.46e-4)" "prognostic unfavorable (1.31e-4)" "unprognostic (2.11e-1)" "prognostic unfavorable (5.24e-4)" "unprognostic (1.27e-1)" "unprognostic (1.67e-2)" "unprognostic (2.71e-2)" "unprognostic (8.22e-2)" "unprognostic (1.85e-1)" "unprognostic (1.43e-3)" "unprognostic (8.31e-2)" "unprognostic (1.04e-1)" "unprognostic (8.22e-2)" "unprognostic (2.30e-1)" "unprognostic (2.12e-1)" "unprognostic (1.08e-1)" 4.6 23.2 47.3 1.4 43.6 0.1 4.5 37.0 101.6 11.8 0.0 4.5 10.3 9.0 0.7 1.1 4.0 9.6 2.3 43.7 93.1 7.8 0.6 4.5 0.9 69.2 29.2 5.4 41.2 21.3 91.9 3.0 62.5 14.4 3.4 25.8 22.1 4.3 1.0 2.4 5.8 4.1 21.1 1.9 16.6 11.2 46.4 0.4 1.0 0.0 1.4 3.1 1.8 57.3 1.4 11.6 0.9 11.0 0.1 0.5 7.7 14.4 6.7 13.3 7.3 17.2 53.8 5.8 76.7 17.5 11.1 4.9 4.4 3.4 4.0 0.1 9.6 0.9 9.2 35.7 28.7 0.0 33.9 32.3 6.5 15.8 4.3 48.1 1.0 5.1 1.8 34.5 6.7 59.4 0.2 0.1 17.2 19.6 19.8 0.0 0.0 1.6 12.1 5.1 51.3 41.2 4.9 36.5 2.3 9.1 34.3 51.3 0.6 44.3 21.6 0.3 0.9 3.9 3.6 0.3 53.8 9.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.3 43.6 37.0 101.6 43.7 93.1 69.2 29.2 62.5 21.1 46.4 57.3 3.2 3.2 16.4 4.2 0.8 2.9 9.4 6.2 2.8 236.6 49.6 30.6 8.6 77.2 5.5 3.7 185.6 0.3 0.5 19.9 0.0 61.7 2.8 25.1 48.2 4.9 132.5 0.0 28.6 39.4 2.7 12.2 34.7 33.4 1.3 3.5 2.5 0.2 1.3 188.4 46.3 32.9 10.2 0.3 0.0 5.4 1.2 1.0 12.4 3.7 0.6 20.8 0.0 5.5 13.1 45.2 22.1 1.9 1.4 23.5 15.3 5.0 3.4 230.3 13.1 0.9 15.2 8.2 4.7 1.0 1.4 1.4 0.7 26.8 29.0 9.1 SFRP5 SARP3 ENSG00000120057 "Secreted frizzled related protein 5" Q5T4F7 10 97766751-97771999 "Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "choroid plexus: 98.7;heart muscle: 78.7;intestine: 36.4;pancreas: 143.2" "Cell type enriched" "Detected in some" 7 "Cholangiocytes: 273.1" "Cancer enriched" "Detected in many" 4 "pancreatic cancer: 30.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 4 "naive CD8 T-cell: 3.6" "Lineage enriched" "Detected in single" 4 "T-cells: 3.6" "Cell line enhanced" "Detected in some" "A549: 2.5;CACO-2: 12.4;RPMI-8226: 4.5;SCLC-21H: 2.0" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 8 "spinal cord: 120.7" "Secreted in other tissues" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 39: CACO-2 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "unprognostic (2.63e-4)" "unprognostic (3.03e-3)" "unprognostic (6.74e-2)" "unprognostic (3.43e-2)" "unprognostic (9.85e-2)" "unprognostic (1.03e-1)" "unprognostic (1.25e-1)" "unprognostic (3.19e-1)" "unprognostic (2.85e-1)" "unprognostic (8.83e-2)" "unprognostic (1.11e-1)" "unprognostic (1.78e-1)" "unprognostic (4.51e-9)" "unprognostic (1.67e-2)" "unprognostic (1.57e-1)" "unprognostic (9.17e-2)" "unprognostic (1.62e-1)" 2.9 9.6 2.8 0.3 3.9 0.3 2.4 1.6 0.6 3.5 98.7 36.4 29.8 1.8 2.2 2.0 2.2 4.1 78.7 5.6 7.5 0.4 8.8 3.4 0.3 3.6 8.3 0.6 143.2 0.0 0.9 0.0 3.6 6.8 0.5 0.2 2.8 4.0 1.3 3.1 26.3 0.4 1.6 0.1 10.5 0.8 14.7 0.1 1.0 2.9 0.1 3.2 4.9 0.2 0.0 2.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.0 0.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 4.5 0.0 0.0 2.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 3.6 0.0 0.0 0.0 0.8 0.0 0.2 2.8 3.9 1.6 0.6 5.6 7.5 3.6 8.3 3.6 1.6 14.7 0.2 0.0 3.2 3.6 0.3 0.3 0.0 0.1 0.0 0.0 0.4 0.0 0.0 7.8 273.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 18.2 0.0 0.0 0.1 0.6 0.0 0.0 0.2 16.8 0.0 3.2 0.0 0.0 0.0 0.0 2.2 0.7 0.0 0.0 0.3 1.3 0.0 0.6 0.0 0.0 1.8 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.2 3.3 2.5 0.0 0.0 0.0 37.8 0.0 0.0 0.2 0.0 1.2 0.4 0.1 5.9 0.0 0.0 0.0 0.1 0.0 0.5 0.0 SFXN2 SLC56A2 ENSG00000156398 "Sideroflexin 2" Q96NB2 10 102714538-102743492 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 17.9;parathyroid gland: 12.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 33.3;Hepatocytes: 21.2;Proximal tubular cells: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "T-47d: 38.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018150, HPA026834" Enhanced Approved Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA018150: AB_1856790, HPA026834: AB_1856791" "unprognostic (1.70e-2)" "prognostic favorable (2.28e-4)" "unprognostic (3.30e-2)" "unprognostic (2.95e-1)" "unprognostic (6.10e-2)" "unprognostic (1.44e-2)" "prognostic favorable (9.95e-4)" "unprognostic (4.24e-2)" "unprognostic (9.69e-2)" "unprognostic (3.98e-2)" "unprognostic (1.32e-1)" "unprognostic (8.98e-3)" "prognostic favorable (2.28e-5)" "unprognostic (1.20e-1)" "unprognostic (2.14e-1)" "unprognostic (3.77e-2)" "prognostic favorable (6.52e-4)" 1.5 1.1 1.2 1.9 2.8 3.0 2.8 3.9 1.7 1.6 3.6 1.9 2.5 2.7 3.6 1.4 3.6 1.1 0.6 1.8 0.8 17.9 4.2 1.6 2.6 1.0 0.5 3.4 3.1 12.7 2.7 3.4 1.2 2.2 3.0 2.7 4.9 1.3 0.7 1.9 1.9 1.1 0.2 2.1 3.3 1.2 1.8 3.2 3.8 0.2 1.9 0.9 0.7 2.1 4.2 2.3 3.5 3.7 1.3 0.9 5.1 1.4 0.6 1.8 0.9 7.2 1.9 9.1 2.7 1.2 1.0 3.0 0.7 4.8 1.0 1.6 2.8 13.1 4.4 4.5 0.6 7.5 1.1 1.0 0.7 1.8 1.8 1.1 1.7 7.7 6.0 4.2 1.1 4.0 11.5 2.5 2.3 4.0 0.8 5.5 4.3 1.3 1.7 3.5 2.6 2.5 1.2 3.1 0.6 1.4 38.4 1.6 1.2 1.4 4.4 1.8 3.1 4.6 6.5 7.9 1.7 9.0 1.2 1.6 0.5 0.2 1.9 0.2 1.7 0.8 1.9 2.0 0.7 2.5 3.0 2.5 0.9 1.9 0.3 1.7 2.0 0.7 1.2 2.8 3.9 1.7 1.8 0.8 1.0 0.5 1.2 0.2 1.8 2.1 1.0 0.0 10.1 5.2 3.8 0.9 3.0 0.8 4.0 6.1 7.3 5.2 2.5 4.3 2.0 1.8 33.3 9.1 2.4 2.5 9.8 1.9 0.8 7.3 4.2 2.2 3.6 4.2 5.4 2.8 4.4 3.2 8.2 10.0 0.0 9.2 5.0 21.2 9.6 0.0 5.5 5.0 0.0 7.5 0.6 0.5 2.1 2.4 0.0 8.4 0.8 1.1 4.1 7.1 2.9 1.4 0.8 1.5 6.7 4.4 2.4 43.1 0.4 15.1 0.0 2.7 1.7 1.2 1.3 3.3 1.3 4.5 2.8 2.6 7.3 2.9 SGMS1 "MGC17342, MOB, SMS1, TMEM23" ENSG00000198964 "Sphingomyelin synthase 1" Q86VZ5 10 50305586-50625163 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 153.1;Microglial cells: 229.5;Oligodendrocyte precursor cells: 313.1;Oligodendrocytes: 422.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 62.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045191 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Nucleoli fibrillar center, Golgi apparatus, Cytosol" "HPA045191: AB_10959605" "unprognostic (1.13e-1)" "unprognostic (5.75e-2)" "unprognostic (1.87e-1)" "unprognostic (9.08e-2)" "unprognostic (8.69e-3)" "unprognostic (8.34e-2)" "unprognostic (7.98e-2)" "unprognostic (2.29e-1)" "unprognostic (1.30e-2)" "unprognostic (5.75e-2)" "unprognostic (9.20e-2)" "unprognostic (2.05e-1)" "prognostic favorable (1.95e-7)" "unprognostic (8.38e-2)" "unprognostic (1.95e-1)" "unprognostic (3.31e-1)" "unprognostic (3.05e-1)" 15.8 19.3 19.8 10.7 27.4 24.0 14.5 21.5 20.3 16.9 33.9 10.1 13.5 11.9 19.9 15.3 16.6 15.4 13.2 17.2 23.0 20.2 27.9 21.9 14.9 29.5 24.1 18.6 13.3 52.9 6.4 24.6 28.5 19.5 11.7 20.2 18.0 16.8 9.9 25.3 16.0 15.8 23.6 11.7 14.3 11.3 23.4 12.0 24.7 10.5 14.5 20.9 13.1 41.3 30.2 14.0 4.0 9.0 14.2 18.6 18.8 19.6 19.7 13.5 12.6 11.7 30.3 22.1 11.3 25.9 12.2 18.7 9.5 20.6 14.0 19.4 10.2 32.7 17.9 9.0 16.5 7.5 7.6 12.1 23.6 18.0 21.7 8.7 19.3 7.9 62.6 32.2 14.6 12.7 3.3 4.2 9.2 13.7 13.7 5.5 18.4 8.8 19.7 31.2 6.2 4.9 14.4 14.2 7.5 11.3 21.4 2.7 27.1 14.6 17.8 14.1 14.6 11.0 9.5 6.3 18.2 12.0 12.1 3.4 9.3 28.4 4.6 4.9 10.3 7.0 6.2 6.8 5.2 6.5 8.2 5.4 16.7 10.1 4.0 3.2 15.6 6.3 19.8 27.4 21.5 20.3 17.2 23.0 29.5 24.1 28.5 23.6 23.4 41.3 17.1 44.8 40.0 106.7 19.9 54.4 28.9 15.6 23.9 20.1 15.8 8.9 26.3 10.0 30.0 29.5 4.2 10.9 15.6 6.2 15.6 17.6 17.0 20.9 10.5 19.6 14.9 32.0 153.1 21.6 7.7 19.8 30.5 32.4 20.8 12.1 17.9 16.0 29.0 5.0 117.2 11.1 4.1 46.5 17.6 30.6 16.1 34.5 12.4 229.5 12.4 17.4 10.3 313.1 422.0 10.7 6.4 10.5 13.7 32.3 18.4 9.3 25.1 36.4 0.0 20.5 27.1 12.8 2.3 18.7 83.4 4.9 20.0 11.8 12.4 25.4 SH2D3C NSP3 ENSG00000095370 "SH2 domain containing 3C" Q8N5H7 9 127738317-127778710 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 52.6;dendritic cells: 29.7;Endothelial cells: 52.2;Hepatic stellate cells: 41.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 53.3;HUVEC TERT2: 60.0;REH: 60.7;RPMI-8226: 46.1;TIME: 50.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047586 Enhanced Supported Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA047586: AB_2680093" "unprognostic (8.33e-2)" "unprognostic (4.77e-3)" "unprognostic (3.28e-2)" "prognostic favorable (9.47e-4)" "unprognostic (5.23e-2)" "prognostic favorable (1.98e-4)" "unprognostic (3.75e-2)" "unprognostic (2.22e-1)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (2.58e-3)" "unprognostic (1.61e-1)" "unprognostic (1.88e-3)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (1.18e-1)" "unprognostic (5.28e-2)" 27.3 7.6 11.2 15.9 10.5 11.2 24.9 11.7 13.2 12.2 2.8 7.6 4.5 15.8 1.2 5.8 12.6 9.2 44.7 10.7 9.6 19.9 4.7 52.2 25.8 8.6 7.5 5.0 4.8 3.9 7.1 15.8 8.4 8.5 1.8 0.8 6.8 3.5 14.6 7.4 15.1 7.3 8.1 47.2 7.3 5.1 8.9 27.8 22.9 11.4 10.5 10.9 9.4 8.0 0.1 0.2 0.9 0.2 0.8 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 19.5 1.1 0.0 1.1 0.7 0.0 0.0 0.0 15.6 0.3 7.3 0.1 0.0 0.3 5.6 53.3 0.3 0.2 0.3 0.1 0.0 60.0 11.6 0.2 20.6 0.0 0.1 5.1 16.8 0.8 0.0 0.0 60.7 0.9 46.1 0.0 0.0 14.5 4.4 0.3 0.1 0.0 1.4 0.1 9.6 50.1 0.0 1.2 0.1 0.1 20.3 22.2 20.3 0.4 4.8 0.0 34.0 29.9 37.8 32.3 94.7 26.4 26.2 18.8 30.4 32.8 29.5 16.6 17.5 82.2 34.6 124.8 59.8 21.6 34.2 11.2 10.5 11.7 13.2 10.7 9.6 8.6 7.5 8.4 8.1 8.9 8.0 52.6 3.2 5.8 0.7 15.9 1.3 0.3 1.9 0.6 3.2 1.1 1.7 10.5 2.8 0.9 0.0 0.0 0.3 29.7 0.0 0.0 0.5 13.8 2.2 2.8 52.2 4.2 3.6 10.8 0.0 0.2 3.1 2.0 0.8 11.4 0.0 41.7 0.7 6.0 3.3 10.7 0.3 0.0 6.0 3.7 16.3 1.2 10.7 1.8 23.4 13.4 3.6 21.6 3.0 0.7 0.1 0.0 0.7 7.6 0.1 0.0 0.1 0.8 2.4 6.6 1.2 12.5 1.8 1.5 0.9 0.4 0.7 15.5 2.0 0.1 0.2 SH3BGRL2 ENSG00000198478 "SH3 domain binding glutamate rich protein like 2" Q9UJC5 6 79631329-79703655 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 161.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 156.3;Excitatory neurons: 86.5;Intestinal goblet cells: 87.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 50.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 11.1" "Lineage enriched" "Detected in many" 10 "granulocytes: 11.1" "Cell line enhanced" "Detected in many" "CACO-2: 81.6;HEL: 41.8;OE19: 99.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047486 Approved Supported Nucleoplasm NA NA 2000000 "Cluster 34: Basophils - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA047486: AB_2680065" "unprognostic (3.48e-2)" "unprognostic (1.95e-1)" "unprognostic (1.75e-2)" "unprognostic (2.28e-2)" "unprognostic (4.21e-1)" "unprognostic (7.77e-2)" "unprognostic (1.07e-1)" "unprognostic (1.60e-2)" "unprognostic (6.92e-2)" "unprognostic (6.53e-3)" "unprognostic (2.78e-1)" "unprognostic (7.94e-2)" "prognostic favorable (2.24e-4)" "unprognostic (1.60e-1)" "unprognostic (1.51e-1)" "unprognostic (2.11e-2)" "unprognostic (1.33e-1)" 26.4 6.9 18.8 7.5 18.6 1.7 21.6 15.6 27.5 22.3 15.1 50.5 35.2 9.9 24.7 55.1 17.8 23.2 6.8 21.4 21.8 15.7 53.1 12.7 5.5 26.7 22.0 4.1 23.3 31.5 16.6 24.0 28.1 26.2 47.9 26.0 161.7 11.4 4.8 11.3 35.6 15.8 24.1 6.6 68.9 2.1 24.2 4.8 59.1 10.1 10.7 12.7 19.7 22.5 8.5 1.5 7.6 1.6 6.7 5.6 18.0 0.5 5.6 1.9 4.0 81.6 16.3 0.1 11.4 0.5 1.6 3.9 7.0 9.2 6.7 0.0 10.2 41.8 1.8 15.8 2.8 1.7 1.1 3.1 7.3 5.8 3.3 2.7 23.8 0.0 16.8 0.0 0.7 1.3 0.0 0.2 6.5 99.7 2.8 0.0 2.2 0.2 2.0 27.3 20.3 22.3 0.5 2.4 0.6 10.3 0.4 3.5 13.6 5.2 3.4 0.1 4.9 12.0 6.0 0.0 0.9 0.0 1.6 11.1 0.2 0.4 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 1.0 2.2 0.0 0.0 0.1 0.0 8.8 18.8 18.6 15.6 27.5 21.4 21.8 26.7 22.0 28.1 24.1 24.2 22.5 83.2 6.4 24.8 20.9 0.9 2.2 4.6 3.3 2.2 13.5 14.8 9.9 6.1 52.9 21.4 22.0 8.4 40.4 1.7 156.3 0.0 14.8 18.1 14.3 3.7 33.8 12.6 7.4 86.5 13.0 3.7 4.6 81.1 21.0 0.0 2.0 44.6 69.6 4.1 13.5 38.1 87.8 4.1 2.9 2.1 20.3 0.6 21.6 16.0 11.2 4.6 8.6 0.0 33.7 24.9 15.0 76.0 4.5 1.3 19.7 48.7 11.3 24.6 12.2 0.0 3.7 4.7 2.5 1.2 21.5 0.9 52.7 1.0 1.8 67.2 29.9 SH3D19 "DKFZp434D0215, EBP, Eve-1, EVE1, Kryn, SH3P19" ENSG00000109686 "SH3 domain containing 19" Q5HYK7 4 151102751-151325605 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 263.9;Oligodendrocytes: 360.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 190.3;ASC TERT1: 161.0;HSkMC: 129.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016424, HPA058562" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA016424: AB_1856814, HPA058562: AB_2683758" "unprognostic (1.09e-1)" "unprognostic (6.14e-2)" "unprognostic (1.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.67e-1)" "unprognostic (2.84e-2)" "unprognostic (1.30e-2)" "unprognostic (5.09e-1)" "unprognostic (7.37e-2)" "unprognostic (1.48e-1)" "unprognostic (6.40e-3)" "unprognostic (1.86e-1)" "prognostic favorable (1.38e-5)" "unprognostic (7.90e-2)" "unprognostic (1.07e-1)" "unprognostic (1.62e-1)" "unprognostic (1.64e-2)" 70.8 15.7 9.8 12.8 14.9 0.2 31.5 6.0 9.6 22.5 104.9 44.2 44.4 23.2 10.7 40.8 23.7 63.7 64.1 6.8 11.6 27.2 49.9 36.2 5.1 8.8 10.3 42.9 15.2 19.9 5.0 27.9 8.8 27.1 48.3 12.8 17.3 40.5 17.7 30.0 49.0 41.4 5.1 7.4 22.6 12.4 11.5 3.9 25.1 33.8 7.9 33.3 20.6 18.6 26.3 19.2 12.1 9.5 190.3 161.0 26.0 31.8 34.0 13.9 14.4 24.9 31.6 0.0 12.5 29.9 22.7 19.2 12.8 36.6 13.5 0.1 10.1 0.0 22.2 26.7 46.0 0.1 0.1 129.1 27.6 20.9 32.0 23.9 81.9 0.0 0.0 0.1 36.9 10.9 0.0 0.4 24.3 40.3 27.6 0.0 0.9 0.4 17.3 18.3 0.9 16.3 22.7 23.0 18.5 24.7 7.5 0.1 59.9 43.6 15.6 19.5 12.9 0.1 0.0 0.1 22.6 0.1 54.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 9.8 14.9 6.0 9.6 6.8 11.6 8.8 10.3 8.8 5.1 11.5 18.6 36.7 22.4 32.5 8.1 2.9 28.6 14.1 12.3 18.8 6.6 20.5 25.0 88.5 34.3 29.2 16.5 14.6 25.9 5.0 103.5 5.9 11.9 4.4 17.6 38.1 29.1 18.6 7.0 55.8 15.4 20.7 77.9 38.7 13.7 21.5 37.5 21.8 46.4 7.4 6.7 30.0 35.6 10.2 4.6 20.2 6.7 62.1 4.8 26.6 74.0 1.2 20.8 5.2 263.9 360.1 21.3 55.9 48.2 3.2 41.5 88.2 27.2 52.4 11.0 13.1 46.0 26.3 2.9 6.0 16.7 38.5 27.2 5.5 20.3 54.0 41.2 SHANK3 "KIAA1650, prosap2, PSAP2, SPANK-2" ENSG00000251322 "SH3 and multiple ankyrin repeat domains 3" 22 50674415-50733298 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.5" "Cell type enhanced" "Detected in many" "Adipocytes: 195.3;Endothelial cells: 65.0;Hepatic stellate cells: 70.3;Microglial cells: 44.0;Oligodendrocytes: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 33.3;TIME: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003446 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA003446: AB_1079958" "unprognostic (3.62e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.40e-4)" "unprognostic (6.02e-2)" "unprognostic (4.17e-1)" "unprognostic (1.72e-3)" "unprognostic (3.41e-2)" "unprognostic (3.13e-1)" "unprognostic (9.67e-2)" "unprognostic (5.62e-2)" "unprognostic (2.09e-2)" "unprognostic (7.52e-2)" "unprognostic (2.47e-2)" "unprognostic (7.81e-2)" "unprognostic (1.19e-1)" "unprognostic (4.89e-2)" "unprognostic (1.41e-1)" 34.9 4.0 38.9 4.9 21.6 1.1 33.5 73.5 54.7 12.8 0.0 7.5 3.4 13.4 2.0 5.2 12.4 5.8 26.2 44.7 14.9 11.9 4.4 20.3 4.2 10.0 15.3 4.3 4.0 3.5 5.2 13.7 2.6 8.3 1.2 0.7 8.2 4.2 23.3 7.1 6.4 5.1 0.0 50.4 5.7 2.2 38.6 1.7 14.8 8.9 1.4 10.7 10.1 16.2 6.6 2.6 6.2 4.8 0.5 1.6 3.2 1.3 0.0 0.4 0.5 1.6 2.4 0.0 4.0 1.0 3.1 1.2 0.9 2.3 0.0 0.0 10.4 8.0 1.8 7.1 1.9 1.8 0.4 2.2 1.8 0.1 0.3 0.1 33.3 1.9 0.2 0.2 0.5 2.6 1.4 0.5 3.2 0.6 2.2 7.5 0.0 1.7 0.4 1.3 2.3 3.0 2.7 0.0 3.1 0.7 0.3 0.7 37.6 0.4 9.3 2.0 0.7 0.3 0.4 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.9 21.6 73.5 54.7 44.7 14.9 10.0 15.3 2.6 0.0 38.6 16.2 195.3 0.0 1.1 4.6 0.5 0.3 0.1 0.5 4.0 1.2 1.3 2.4 27.6 0.0 0.8 0.0 0.0 0.0 0.8 0.1 0.0 0.0 2.9 3.9 2.4 65.0 2.4 0.0 28.3 0.0 0.0 3.3 0.0 1.5 0.0 0.3 70.3 6.5 0.4 0.0 21.7 0.0 2.0 3.1 0.0 0.4 0.0 0.3 0.0 44.0 0.0 1.4 0.0 25.1 31.3 0.1 0.0 0.4 0.0 0.2 0.0 0.9 0.9 0.0 0.0 1.0 3.8 0.2 0.8 1.0 0.3 0.0 0.6 0.7 0.1 0.3 SHISAL2A "FAM159A, MGC52498" ENSG00000182183 "Shisa like 2A" Q6UWV7 1 52633168-52669683 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.7;intestine: 3.7;lymphoid tissue: 5.6" "Cell type enhanced" "Detected in some" "B-cells: 4.3;dendritic cells: 9.8;Endometrial stromal cells: 2.6;Hofbauer cells: 1.8;Macrophages: 2.2;T-cells: 6.4" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "hypothalamus: 8.7" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 10.1;NK-cells: 5.9;T-cells: 7.0" "Cell line enhanced" "Detected in some" "Daudi: 4.1;Karpas-707: 9.4;NB-4: 2.9;RPMI-8226: 13.0" "Region enhanced" "Detected in some" "hypothalamus: 4.0" "Low region specificity" "Detected in some" HPA030744 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 7: Non-specific - Mitochondria" "HPA030744: AB_10963060" "unprognostic (7.94e-6)" "unprognostic (8.50e-3)" "unprognostic (8.29e-3)" "unprognostic (2.69e-3)" "unprognostic (2.54e-1)" "unprognostic (9.67e-4)" "unprognostic (1.98e-1)" "unprognostic (1.18e-2)" "unprognostic (2.22e-2)" "unprognostic (4.45e-2)" "unprognostic (2.98e-2)" "unprognostic (1.20e-1)" "unprognostic (1.31e-3)" "unprognostic (7.27e-2)" "unprognostic (2.79e-1)" "unprognostic (6.50e-2)" "unprognostic (2.64e-2)" 0.4 0.2 0.8 2.3 0.7 1.7 0.2 0.8 1.0 1.0 0.4 0.4 0.3 0.4 0.7 0.2 0.6 0.3 0.1 0.5 8.7 0.3 0.2 0.7 5.6 1.0 1.6 0.0 0.2 0.0 2.0 0.1 1.1 0.4 0.3 0.1 0.3 0.3 0.3 0.0 3.7 0.0 0.9 5.4 0.5 0.8 2.5 1.0 0.7 0.2 5.2 0.3 0.2 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 2.9 1.6 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 7.0 0.0 3.9 10.1 6.2 5.6 0.0 9.8 4.3 2.6 0.0 5.9 0.0 0.0 2.1 1.6 0.8 0.7 0.8 1.0 0.5 8.7 1.0 1.6 1.1 0.9 2.5 1.2 0.6 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 9.8 0.0 0.0 0.0 0.0 0.6 2.6 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.4 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 6.4 0.5 0.0 0.0 SHMT1 "CSHMT, MGC15229, MGC24556, SHMT" ENSG00000176974 "Serine hydroxymethyltransferase 1" P34896 17 18327860-18363563 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 168.5;liver: 398.7" "Group enriched" "Detected in many" 4 "Hepatocytes: 307.7;Proximal tubular cells: 435.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023314, HPA078682" Enhanced Supported Nucleoplasm,Cytosol NA NA 1500000 "Cluster 44: Non-specific - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA023314: AB_1856830, HPA078682: " "unprognostic (4.76e-2)" "unprognostic (1.98e-2)" "unprognostic (5.46e-2)" "unprognostic (3.76e-1)" "unprognostic (2.45e-1)" "unprognostic (8.44e-3)" "prognostic favorable (2.52e-4)" "unprognostic (7.55e-3)" "unprognostic (4.50e-1)" "unprognostic (2.42e-1)" "unprognostic (2.14e-1)" "unprognostic (1.70e-1)" "prognostic favorable (8.54e-6)" "unprognostic (1.70e-2)" "unprognostic (2.66e-1)" "unprognostic (2.57e-3)" "unprognostic (4.04e-2)" 37.5 9.4 8.1 4.0 9.4 9.5 36.3 12.6 9.5 13.6 7.1 17.5 13.8 7.6 4.9 59.2 13.1 7.7 5.7 8.8 8.5 168.5 398.7 10.3 9.0 10.8 9.3 11.7 8.8 85.7 4.1 7.7 10.7 10.1 6.1 3.1 30.0 10.0 18.8 22.6 24.4 3.7 8.0 21.7 13.3 12.8 9.4 21.1 23.5 18.6 17.6 11.5 19.3 16.0 39.6 28.9 5.5 34.5 29.9 15.8 63.0 11.3 10.3 30.8 31.2 22.1 22.5 26.8 27.8 3.6 16.4 18.8 32.4 39.7 24.3 17.3 30.6 13.0 39.9 21.6 7.2 4.4 11.0 21.1 13.6 23.1 7.2 10.9 9.7 32.3 10.0 10.9 11.3 12.4 46.0 13.9 17.4 43.6 5.1 29.7 48.5 34.7 69.3 17.0 24.0 5.3 82.7 14.9 21.4 50.2 64.5 19.4 2.6 5.7 14.0 71.4 17.6 10.7 20.5 7.1 10.3 12.7 16.5 10.2 4.7 5.2 5.3 5.9 8.1 4.4 6.6 5.5 3.5 3.7 6.8 6.4 0.2 8.5 5.2 1.1 11.2 4.3 8.1 9.4 12.6 9.5 8.8 8.5 10.8 9.3 10.7 8.0 9.4 16.0 11.2 12.8 31.0 3.3 10.4 10.3 21.7 16.5 18.8 3.1 22.7 13.8 2.7 42.9 11.2 36.8 4.2 23.7 5.2 8.9 82.2 13.7 10.9 6.2 1.9 7.4 1.2 28.0 5.2 7.7 76.1 8.0 9.2 10.1 8.2 9.9 13.6 307.7 39.6 0.0 4.8 12.9 4.1 36.8 3.5 5.5 5.9 17.2 12.4 9.4 4.4 33.8 5.2 2.0 11.4 5.3 9.7 3.0 20.3 5.9 53.7 435.7 3.5 4.2 19.7 8.1 4.4 30.0 21.4 35.4 10.5 8.5 10.1 4.9 32.2 10.9 SIAE "CSE-C, LSE, MGC87009, YSG2" ENSG00000110013 "Sialic acid acetylesterase" Q9HAT2 11 124633113-124695707 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 104.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 58.0;Cardiomyocytes: 59.5;Distal enterocytes: 102.4;Paneth cells: 53.0;Proximal enterocytes: 51.6;Undifferentiated cells: 63.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 7.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 88.6;ASC TERT1: 91.3;HSkMC: 98.9;OE19: 97.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038052, HPA038053" Approved "Intracellular and membrane" NA NA 2200000 "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA038052: AB_10671518, HPA038053: AB_10673039" "unprognostic (9.97e-2)" "unprognostic (1.28e-2)" "unprognostic (2.48e-3)" "prognostic favorable (4.66e-5)" "unprognostic (3.30e-2)" "unprognostic (5.20e-2)" "unprognostic (4.90e-2)" "unprognostic (4.32e-2)" "unprognostic (1.18e-1)" "unprognostic (2.26e-1)" "unprognostic (2.45e-1)" "unprognostic (9.19e-2)" "prognostic favorable (4.42e-11)" "unprognostic (7.24e-2)" "unprognostic (3.22e-1)" "unprognostic (4.49e-2)" "unprognostic (1.92e-2)" 18.7 17.3 16.8 11.8 21.6 3.7 15.9 26.9 19.8 13.0 38.9 97.8 34.3 7.1 34.3 13.6 19.3 16.7 43.8 16.1 27.1 62.1 43.4 20.6 5.8 25.3 23.7 5.7 17.3 45.3 14.4 11.8 24.7 20.4 104.4 6.2 18.4 15.3 26.7 13.0 35.8 10.4 23.0 9.1 19.0 10.3 24.9 3.7 54.0 33.3 6.7 16.8 7.8 26.3 8.9 14.0 8.0 34.6 88.6 91.3 20.9 16.8 24.0 4.3 2.6 10.9 61.4 5.5 24.2 21.5 9.4 17.3 12.8 18.7 4.2 26.0 3.9 8.6 3.7 11.1 41.8 0.7 7.2 98.9 24.9 11.4 17.3 58.5 30.6 11.0 7.1 37.5 14.8 16.5 0.2 0.6 5.0 97.7 28.5 3.2 0.2 8.4 51.4 12.1 2.4 5.1 46.5 18.6 8.0 24.0 36.8 3.2 34.1 23.6 4.3 26.5 4.0 9.4 7.5 0.7 8.3 4.6 9.8 7.6 2.9 0.1 0.4 2.1 0.3 0.5 1.3 0.6 1.9 0.7 1.7 1.1 0.5 0.2 3.7 0.5 0.6 1.8 16.8 21.6 26.9 19.8 16.1 27.1 25.3 23.7 24.7 23.0 24.9 26.3 4.2 19.2 58.0 11.8 2.4 3.2 6.3 6.7 7.4 6.5 10.1 4.3 59.5 12.8 9.4 36.8 0.0 7.6 0.6 102.4 9.8 15.2 14.0 9.1 9.3 6.9 14.5 5.2 15.0 3.8 8.8 7.5 12.8 14.0 1.3 3.9 8.9 30.0 4.5 5.0 9.1 31.0 4.1 3.5 1.6 12.0 3.1 4.3 3.6 6.5 4.5 1.9 1.0 8.0 6.7 5.2 53.0 1.2 3.9 7.4 51.6 26.2 11.9 1.8 0.0 4.9 7.9 14.8 9.6 12.2 5.3 6.7 2.0 8.9 63.6 7.1 SIGIRR "IL-1R8, TIR8" ENSG00000185187 "Single Ig and TIR domain containing" Q6IA17 11 405716-417455 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 401.9;Proximal tubular cells: 627.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 136.0;MCF7: 74.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA023188 Approved Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoli fibrillar center, Cytosol" "HPA023188: AB_1856856" "unprognostic (6.21e-3)" "prognostic favorable (7.44e-5)" "unprognostic (7.30e-2)" "prognostic favorable (1.34e-5)" "unprognostic (6.85e-2)" "prognostic favorable (9.08e-4)" "unprognostic (4.03e-1)" "unprognostic (1.39e-2)" "unprognostic (8.44e-2)" "unprognostic (1.67e-1)" "unprognostic (2.32e-2)" "unprognostic (1.31e-1)" "prognostic favorable (7.61e-6)" "unprognostic (1.00e-3)" "unprognostic (1.76e-1)" "unprognostic (7.63e-2)" "prognostic favorable (1.54e-5)" 21.3 6.8 47.5 32.4 46.6 33.2 22.3 47.3 58.7 21.5 42.5 45.0 28.9 20.5 19.1 19.1 29.9 19.9 36.0 46.1 47.4 68.4 87.7 33.9 45.8 52.4 47.6 12.9 47.6 16.3 15.8 9.5 51.8 32.8 13.7 5.6 33.4 17.4 6.7 9.7 46.4 10.3 48.0 68.3 42.0 7.8 48.9 18.5 31.0 10.0 18.0 23.1 17.9 49.9 22.2 59.6 3.7 20.7 3.2 16.9 42.7 3.3 5.1 10.0 8.8 27.7 136.0 6.2 16.2 19.1 1.1 31.4 9.7 11.2 1.6 19.0 35.9 12.7 11.8 0.7 10.6 11.0 20.4 9.2 2.3 1.6 1.3 5.6 29.0 24.0 12.7 0.4 2.8 74.4 31.4 35.6 21.3 44.9 32.6 38.3 0.0 21.6 7.1 14.8 35.9 17.6 0.4 20.1 26.4 9.0 25.4 8.6 34.4 3.0 3.9 5.0 0.0 7.4 13.5 16.2 13.3 24.0 11.6 77.8 42.3 39.0 123.6 48.4 98.7 37.6 101.8 108.3 43.0 28.7 91.7 90.1 22.0 102.4 61.8 16.3 106.1 82.6 47.5 46.6 47.3 58.7 46.1 47.4 52.4 47.6 51.8 48.0 48.9 49.9 83.1 28.9 34.4 16.6 46.5 16.3 34.1 33.2 43.9 8.6 44.3 40.0 21.3 72.9 35.0 55.2 12.5 17.7 105.6 163.9 62.6 54.1 1.0 47.9 15.0 62.7 78.9 14.7 2.6 73.3 11.4 37.0 80.0 40.7 40.6 15.4 79.6 401.9 51.2 26.9 2.5 106.1 63.1 52.7 31.9 5.1 31.4 61.7 85.4 4.7 46.9 109.2 218.3 1.5 10.4 79.6 153.7 29.7 37.9 24.6 105.3 627.4 75.8 19.2 26.3 21.2 34.7 6.0 69.8 21.1 12.8 10.1 117.3 10.2 93.6 43.6 SIGLEC11 ENSG00000161640 "Sialic acid binding Ig like lectin 11" Q96RL6 19 49948985-49961172 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 23.1;ovary: 65.5" "Group enriched" "Detected in some" 7 "Granulosa cells: 196.9;Theca cells: 192.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 1.4;non-classical monocyte: 1.3" "Group enriched" "Detected in many" 6 "granulocytes: 1.4;monocytes: 1.3" "Cell line enriched" "Detected in single" 16 "HEL: 10.1" "HPA052132, HPA060278" Approved Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" Nucleoplasm "HPA052132: , HPA060278: AB_2684240" "unprognostic (1.07e-1)" "unprognostic (2.85e-3)" "unprognostic (1.56e-1)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (3.35e-2)" "unprognostic (9.93e-2)" "unprognostic (8.88e-2)" "unprognostic (1.27e-1)" "unprognostic (2.06e-1)" "unprognostic (3.63e-1)" "unprognostic (1.20e-1)" "unprognostic (8.79e-4)" "unprognostic (2.11e-1)" "unprognostic (1.41e-1)" "unprognostic (9.95e-3)" "unprognostic (5.38e-2)" 1.1 7.3 0.5 1.8 0.8 0.4 0.4 0.4 0.7 0.3 0.6 0.5 0.8 0.3 0.2 0.1 0.9 0.3 0.4 0.6 0.6 0.4 1.7 1.7 0.6 1.4 1.0 65.5 2.7 0.1 0.2 1.8 1.3 0.2 0.4 0.2 0.3 0.2 0.2 0.2 1.0 1.2 0.8 23.1 4.7 1.5 1.6 0.1 0.2 0.1 0.0 0.6 0.2 1.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 10.1 0.1 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.3 1.4 0.0 1.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.2 1.3 0.1 0.0 0.1 0.5 0.8 0.4 0.7 0.6 0.6 1.4 1.0 1.3 0.8 1.6 1.4 0.1 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 19.6 0.0 0.6 0.2 0.3 1.0 0.0 0.0 0.0 1.1 0.1 4.3 0.0 0.3 0.0 196.9 5.3 0.6 7.9 0.0 0.0 0.0 0.0 26.8 0.2 0.1 0.0 6.1 0.0 5.6 1.3 0.0 0.0 0.0 0.0 2.7 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.2 7.5 1.7 0.7 0.0 0.1 0.1 0.2 192.3 0.0 0.0 SIGLEC5 "CD170, CD33L2, OB-BP2, SIGLEC-5" ENSG00000105501 "Sialic acid binding Ig like lectin 5" O15389 19 51611927-51645545 "CD markers, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 14.7;lymphoid tissue: 12.4" "Cell type enhanced" "Detected in some" "granulocytes: 8.2;Hofbauer cells: 5.6;Kupffer cells: 10.4;Macrophages: 4.4;monocytes: 3.0" "Cancer enriched" "Detected in single" 5 "urothelial cancer: 1.7" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 4 "neutrophil: 152.5;non-classical monocyte: 49.3" "Group enriched" "Detected in many" 6 "granulocytes: 152.5;monocytes: 49.3" "Group enriched" "Detected in some" 5 "HMC-1: 59.2;U-937: 25.6" "HPA009085, CAB024900" Supported NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB024900: , HPA009085: AB_1079965" "unprognostic (1.83e-1)" "unprognostic (1.94e-1)" "unprognostic (2.02e-2)" "unprognostic (1.03e-2)" "unprognostic (4.39e-2)" "unprognostic (1.62e-2)" "unprognostic (1.73e-1)" "unprognostic (1.01e-1)" "unprognostic (3.28e-1)" "unprognostic (7.44e-2)" "unprognostic (1.01e-1)" "unprognostic (4.05e-1)" "unprognostic (3.71e-4)" "unprognostic (4.37e-2)" "unprognostic (3.55e-3)" "unprognostic (4.02e-1)" "unprognostic (1.95e-1)" 1.4 0.4 0.3 6.6 0.6 14.7 0.2 0.3 1.2 0.2 0.0 0.7 0.1 0.3 0.0 0.3 0.7 0.7 0.4 0.3 0.3 0.3 1.5 3.4 3.1 0.4 0.3 0.1 0.2 0.3 0.1 0.8 0.5 0.3 0.7 0.2 0.3 0.1 0.0 0.0 2.0 0.9 0.4 12.4 0.6 0.8 0.4 0.7 0.2 0.4 2.2 1.5 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 59.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.6 0.0 15.5 22.2 0.5 0.0 24.2 0.0 2.5 0.0 0.0 15.6 2.0 0.0 0.0 152.5 0.7 49.3 5.0 0.0 8.4 0.3 0.6 0.3 1.2 0.3 0.3 0.4 0.3 0.5 0.4 0.4 0.6 0.0 0.0 0.0 0.3 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.3 0.0 0.0 8.2 0.0 0.0 0.0 5.6 0.0 0.2 0.0 0.0 10.4 1.2 0.5 0.3 4.4 0.0 1.0 3.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 SIGLEC9 CD329 ENSG00000129450 "Sialic acid binding Ig like lectin 9" Q9Y336 19 51124906-51136651 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.7" "Cell type enhanced" "Detected in some" "Hofbauer cells: 42.1;Kupffer cells: 39.8;Langerhans cells: 13.4;Macrophages: 26.8;monocytes: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 198.9;intermediate monocyte: 182.5;myeloid DC: 169.1;neutrophil: 212.0;non-classical monocyte: 121.9" "Group enriched" "Detected in many" 13 "dendritic cells: 169.1;granulocytes: 212.0;monocytes: 198.9" "Group enriched" "Detected in some" 10 "Karpas-707: 23.4;RPMI-8226: 16.5" HPA010682 Uncertain NA NA 270000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA010682: AB_1079968" "unprognostic (2.31e-1)" "unprognostic (3.99e-2)" "unprognostic (1.03e-2)" "unprognostic (1.36e-1)" "unprognostic (4.69e-2)" "unprognostic (6.86e-2)" "unprognostic (5.10e-2)" "unprognostic (2.10e-1)" "unprognostic (1.31e-1)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (7.03e-3)" "prognostic unfavorable (6.17e-5)" "unprognostic (6.56e-2)" "unprognostic (7.38e-3)" "unprognostic (2.95e-1)" "unprognostic (1.73e-1)" 8.0 5.4 2.0 17.9 2.1 9.0 1.9 2.2 4.3 1.4 2.8 2.1 1.7 0.9 0.2 0.9 2.5 5.0 2.1 1.9 3.4 1.4 5.5 8.3 5.0 5.4 4.0 3.2 1.2 4.1 0.9 7.9 5.0 1.1 2.4 0.3 1.5 0.9 0.4 0.5 2.2 6.4 4.0 20.7 1.4 1.7 6.2 1.4 0.9 1.3 2.5 5.4 0.8 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 23.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 2.0 1.5 0.0 17.3 198.9 1.6 15.2 182.5 8.6 0.2 2.5 5.8 169.1 0.1 0.6 2.7 212.0 3.1 121.9 9.2 0.9 84.9 2.0 2.1 2.2 4.3 1.9 3.4 5.4 4.0 5.0 4.0 6.2 5.9 0.1 0.0 0.5 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 1.3 0.0 0.0 0.2 2.7 0.0 0.0 0.0 1.8 0.0 0.1 1.1 0.0 0.0 0.2 0.0 0.4 0.5 0.0 0.0 0.0 0.1 5.3 0.8 42.1 0.0 0.2 0.0 0.0 39.8 13.4 0.4 5.0 26.8 0.0 5.6 10.4 0.0 7.2 0.0 0.1 0.0 0.0 2.2 0.4 0.0 0.0 0.1 0.0 0.0 6.6 0.0 0.1 0.0 0.1 0.0 0.1 0.3 1.3 2.8 0.0 0.0 SIPA1 SPA1 ENSG00000213445 "Signal-induced proliferation-associated 1" Q96FS4 11 65638101-65650918 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 95.6" "Cell type enhanced" "Detected in many" "dendritic cells: 82.5;NK-cells: 88.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020833, HPA039867" Enhanced Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoli "Nucleoplasm, Golgi apparatus, Plasma membrane" "CAB020833: , HPA039867: AB_2676716" "unprognostic (6.10e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.42e-4)" "unprognostic (1.35e-2)" "unprognostic (2.93e-1)" "unprognostic (2.32e-2)" "unprognostic (3.35e-2)" "unprognostic (1.09e-1)" "unprognostic (3.30e-2)" "unprognostic (6.44e-2)" "unprognostic (5.85e-2)" "unprognostic (4.86e-2)" "prognostic unfavorable (3.52e-6)" "unprognostic (1.60e-1)" "unprognostic (2.78e-2)" "unprognostic (1.14e-2)" "unprognostic (1.49e-1)" 21.6 17.2 16.4 48.7 15.5 53.8 16.2 14.1 16.8 20.6 10.3 24.0 12.5 20.9 3.4 14.3 19.5 16.0 25.7 15.8 13.2 17.0 15.0 37.0 60.7 22.3 16.0 13.1 8.4 3.5 7.5 19.4 19.5 17.1 6.0 0.9 14.1 10.0 10.0 8.1 37.8 12.0 19.5 95.6 15.9 4.7 24.5 21.3 14.9 6.4 32.5 18.8 15.3 21.0 1.6 13.3 9.1 20.1 5.4 11.1 21.7 14.9 12.7 11.7 11.3 3.9 14.5 21.3 33.2 7.6 0.4 7.8 3.4 5.1 3.9 22.7 8.1 52.6 20.7 7.4 9.6 21.5 21.5 11.4 2.3 16.2 2.1 11.5 34.4 21.8 30.3 9.2 5.8 5.8 8.6 36.1 6.4 5.4 12.3 38.8 5.1 19.3 4.4 0.8 3.4 20.9 7.5 12.6 31.7 8.5 9.6 32.5 49.2 14.2 28.7 15.2 3.0 14.1 12.2 48.4 19.5 33.0 42.0 3.2 3.3 9.3 5.8 3.9 4.1 4.1 2.8 3.7 2.3 4.7 2.0 3.1 11.1 4.7 4.8 2.1 3.0 3.0 16.4 15.5 14.1 16.8 15.8 13.2 22.3 16.0 19.5 19.5 24.5 21.0 22.5 6.4 5.2 7.5 59.0 6.8 24.7 23.2 17.6 2.1 24.8 26.5 7.2 21.5 19.2 23.9 0.0 10.1 82.5 16.5 37.2 19.8 3.0 8.3 6.8 26.8 21.0 31.6 0.1 14.5 19.6 12.2 11.2 14.9 7.0 37.1 42.8 22.0 38.4 5.0 0.2 12.8 30.5 44.4 11.4 9.8 8.1 40.2 10.6 14.0 23.7 7.6 88.6 0.5 4.0 27.2 12.7 13.2 29.6 29.0 39.0 20.7 6.0 1.8 13.1 7.4 20.9 0.8 13.8 14.4 11.1 13.5 50.4 30.9 14.3 31.9 SIRPB1 "CD172b, SIRP-BETA-1" ENSG00000101307 "Signal regulatory protein beta 1" "O00241, Q5TFQ8" 20 1561385-1620061 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 52.2;lung: 19.4;lymphoid tissue: 28.6" "Cell type enhanced" "Detected in some" "dendritic cells: 10.9;Hofbauer cells: 14.7;Kupffer cells: 29.4;Macrophages: 30.9;monocytes: 26.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "neutrophil: 1594.8" "Group enriched" "Detected in all" 6 "granulocytes: 1594.8;monocytes: 502.2" "Group enriched" "Detected in some" 4 "HMC-1: 54.0;NB-4: 76.2;THP-1: 58.9" HPA047463 Uncertain Uncertain Vesicles,Centrosome NA NA 44000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles Centrosome "HPA047463: AB_2680057" "unprognostic (1.88e-2)" "unprognostic (6.19e-2)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (5.38e-2)" "unprognostic (1.60e-1)" "unprognostic (4.40e-2)" "unprognostic (7.18e-2)" "unprognostic (4.11e-3)" "unprognostic (9.12e-2)" "unprognostic (6.31e-2)" "unprognostic (4.57e-2)" "unprognostic (2.65e-3)" "unprognostic (5.76e-2)" "unprognostic (2.39e-3)" "unprognostic (5.00e-3)" "unprognostic (1.19e-2)" 5.4 1.6 1.3 28.6 1.3 52.2 1.9 1.2 4.2 1.2 0.1 2.1 1.5 0.8 0.8 1.3 2.2 11.2 1.6 1.4 0.8 1.2 3.1 19.4 11.0 0.7 0.8 0.7 1.3 0.3 0.6 2.8 1.3 0.8 1.8 1.2 1.7 0.9 0.8 0.8 2.8 3.2 0.9 24.5 1.5 0.6 2.1 4.5 0.9 1.5 4.3 8.1 0.8 1.9 0.2 0.0 0.2 0.1 0.3 0.5 0.2 0.4 0.1 0.2 0.0 0.2 0.1 0.1 0.8 0.4 7.1 0.3 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.2 14.9 54.0 0.1 0.2 0.3 0.0 8.0 0.5 1.1 0.0 0.2 0.4 0.1 0.0 76.2 0.2 0.0 3.3 0.2 0.0 0.1 10.8 0.3 0.1 0.2 0.2 0.0 0.5 0.0 0.0 58.9 1.6 0.7 0.1 0.4 0.3 0.1 0.1 0.1 1.1 13.4 0.2 6.1 502.2 868.9 7.3 419.7 10.3 2.8 6.5 5.7 175.2 3.4 8.8 5.5 1594.8 8.2 357.6 165.7 11.8 287.0 1.3 1.3 1.2 4.2 1.4 0.8 0.7 0.8 1.3 0.9 2.1 1.9 0.6 3.2 5.2 0.3 1.2 0.0 0.1 0.2 0.6 0.2 0.1 0.0 0.5 0.0 1.6 0.0 0.0 0.2 10.9 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 1.3 0.3 0.0 0.1 0.7 0.0 0.2 7.0 0.0 1.8 0.2 14.7 0.0 0.1 0.0 0.0 29.4 0.0 0.0 0.0 30.9 0.0 0.0 26.7 0.1 0.0 0.5 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 1.8 0.0 0.0 0.0 SIRPG "bA77C3.1, CD172g, SIRP-B2, SIRPB2, SIRPgamma" ENSG00000089012 "Signal regulatory protein gamma" Q9P1W8 20 1629152-1657779 "CD markers, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 39.1" "Group enriched" "Detected in some" 8 "Early spermatids: 48.9;Late spermatids: 14.1;T-cells: 41.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 369.4" "Lineage enriched" "Detected in many" 6 "T-cells: 369.4" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 4.8;JURKAT: 10.7;NB-4: 13.8;RT4: 3.6;THP-1: 2.3" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 24: NB-4 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (3.35e-3)" "unprognostic (4.09e-3)" "unprognostic (7.32e-3)" "prognostic favorable (1.05e-6)" "unprognostic (4.23e-3)" "prognostic favorable (2.24e-4)" "unprognostic (4.49e-2)" "unprognostic (1.30e-2)" "prognostic favorable (7.36e-7)" "unprognostic (1.62e-2)" "unprognostic (6.90e-2)" "unprognostic (2.52e-1)" "prognostic unfavorable (1.47e-6)" "unprognostic (1.03e-1)" "unprognostic (2.18e-1)" "unprognostic (1.40e-2)" "unprognostic (2.95e-3)" 0.4 0.7 0.0 12.9 0.0 2.9 0.9 0.0 0.2 1.0 0.0 2.5 1.8 0.4 0.2 1.1 0.4 2.3 0.6 0.0 0.0 0.3 1.0 1.5 34.3 0.2 0.0 0.3 0.2 0.0 0.1 0.2 0.1 0.7 3.0 0.0 1.2 0.6 0.0 0.3 5.8 0.7 0.1 9.4 3.0 0.3 0.0 39.1 0.7 0.1 28.1 3.3 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 0.0 0.0 0.0 0.0 4.8 0.0 10.7 0.0 0.0 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.1 0.4 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.9 1.5 1.2 67.6 0.7 186.4 0.7 207.6 157.7 0.9 0.7 215.8 176.2 6.0 59.1 1.1 6.7 369.4 101.6 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.2 0.3 0.0 0.0 1.3 1.4 0.3 0.0 0.0 0.0 0.0 0.3 0.4 0.4 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 48.9 0.0 0.0 0.3 0.0 0.0 2.8 0.0 0.0 0.2 0.5 0.1 1.3 0.0 0.4 0.2 0.0 0.0 0.4 0.2 0.0 1.0 0.4 14.1 0.3 0.7 0.0 1.0 1.4 0.0 2.1 0.0 0.3 0.0 0.0 0.0 1.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.0 0.0 0.0 41.3 0.0 0.0 0.0 SLAMF1 "CD150, SLAM" ENSG00000117090 "Signaling lymphocytic activation molecule family member 1" Q13291 1 160608106-160647295 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Cell adhesion, Host-virus interaction, Immunity, Innate immunity, Phagocytosis" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 76.6" "Cell type enhanced" "Detected in some" "B-cells: 29.8;Melanocytes: 14.2;monocytes: 22.9;Plasma cells: 49.2;T-cells: 35.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 66.3" "Group enriched" "Detected in many" 10 "B-cells: 22.7;T-cells: 66.3" "Cell line enriched" "Detected in some" 104 "HDLM-2: 195.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002438, HPA069319" Enhanced "Secreted to blood" NA NA 350000 "Cluster 13: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB002438: AB_564011, HPA069319: AB_2732129" "unprognostic (2.99e-3)" "unprognostic (3.33e-4)" "unprognostic (2.93e-4)" "unprognostic (1.38e-4)" "unprognostic (5.87e-2)" "unprognostic (6.06e-5)" "unprognostic (1.64e-2)" "unprognostic (1.70e-3)" "unprognostic (1.69e-2)" "unprognostic (2.74e-4)" "unprognostic (6.12e-2)" "unprognostic (3.58e-1)" "unprognostic (1.24e-7)" "unprognostic (2.46e-1)" "unprognostic (8.46e-2)" "unprognostic (1.22e-1)" "unprognostic (2.18e-2)" 1.1 0.5 0.0 13.6 0.0 6.6 1.6 0.0 0.1 1.1 0.3 2.6 3.7 0.4 0.1 1.4 0.4 2.3 1.1 0.0 0.0 0.9 0.9 2.1 21.6 0.3 0.0 0.4 0.3 0.1 0.1 3.0 0.1 0.6 3.0 0.0 1.7 0.3 0.3 0.7 3.9 0.9 0.1 6.7 3.9 0.2 0.1 76.6 0.6 0.0 19.1 8.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 195.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.4 0.0 1.8 0.0 0.1 0.2 0.0 10.7 0.0 66.3 16.5 46.3 33.0 0.3 22.7 17.5 4.4 0.6 0.0 0.1 4.4 61.7 9.5 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.1 1.4 0.0 5.2 0.0 29.8 2.0 0.1 0.0 0.0 0.0 0.7 0.3 0.3 0.0 0.6 1.8 0.0 0.0 4.8 0.0 0.0 0.0 4.1 0.1 0.1 2.0 0.0 0.0 0.0 0.0 0.0 1.2 0.5 0.0 1.3 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.8 10.7 8.5 0.0 5.2 14.2 1.0 22.9 0.0 0.0 0.5 0.1 0.0 0.0 0.0 49.2 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.8 0.1 0.1 0.0 1.7 0.1 35.6 0.0 0.1 0.1 SLAMF6 "CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000" ENSG00000162739 "SLAM family member 6" Q96DU3 1 160485030-160523262 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 61.7" "Cell type enhanced" "Detected in some" "B-cells: 23.6;dendritic cells: 19.7;Late spermatids: 22.1;NK-cells: 45.3;Plasma cells: 21.4;T-cells: 26.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Daudi: 88.2;U-698: 127.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA051363, HPA051903" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA051363: AB_2681454, HPA051903: AB_2681658" "prognostic favorable (9.42e-4)" "prognostic favorable (2.78e-4)" "unprognostic (8.65e-2)" "prognostic favorable (9.53e-4)" "unprognostic (5.85e-2)" "prognostic favorable (7.34e-5)" "unprognostic (3.16e-3)" "unprognostic (9.78e-2)" "prognostic favorable (1.25e-4)" "unprognostic (2.31e-3)" "unprognostic (2.09e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.78e-1)" "unprognostic (1.01e-1)" "unprognostic (2.33e-2)" "unprognostic (8.21e-3)" 1.7 1.1 0.2 20.6 0.2 3.2 2.2 0.8 0.4 2.0 0.3 3.8 2.7 1.3 1.4 2.1 1.3 4.6 1.0 0.2 0.1 0.9 4.0 4.4 61.7 0.3 0.1 1.2 0.9 0.2 0.2 1.8 0.3 1.3 3.5 0.1 2.2 0.5 0.4 0.6 13.8 1.4 0.1 32.2 5.5 1.2 0.4 19.3 1.7 0.5 48.6 5.7 1.2 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 6.7 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.6 0.8 0.1 0.0 0.0 21.8 1.3 0.1 0.7 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.2 0.0 0.0 0.1 14.2 127.4 0.0 0.6 0.0 11.2 0.3 23.1 56.1 1.0 38.9 36.2 35.6 71.4 0.3 35.4 19.5 39.5 2.5 41.3 3.1 1.0 45.6 22.2 0.2 0.2 0.8 0.4 0.2 0.1 0.3 0.1 0.3 0.1 0.4 0.3 0.1 0.0 1.3 0.0 23.6 0.4 0.2 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 19.7 0.1 0.0 0.1 9.4 0.1 0.1 0.3 0.0 3.2 0.0 0.2 0.0 0.4 0.5 0.1 1.3 0.0 3.3 1.1 1.1 0.0 0.0 0.0 0.0 4.3 0.8 22.1 0.0 1.1 0.0 0.0 1.6 0.0 45.3 0.0 0.0 0.1 0.1 0.0 21.4 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.2 0.1 0.3 0.0 26.1 0.0 0.0 0.0 SLAMF7 "19A, CD319, CRACC, CS1" ENSG00000026751 "SLAM family member 7" Q9NQ25 1 160739057-160754821 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.6;lymphoid tissue: 62.0;stomach 1: 34.2" "Cell type enhanced" "Detected in many" "dendritic cells: 58.3;monocytes: 120.2;NK-cells: 76.2;Plasma cells: 240.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 5 "U-266/70: 283.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015445, HPA055945, HPA061654" Enhanced Approved Vesicles NA NA 1200000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "CAB015445: AB_1121905, HPA055945: AB_2682980, HPA061654: AB_2684576" "unprognostic (5.82e-3)" "unprognostic (1.81e-2)" "unprognostic (1.84e-3)" "unprognostic (2.12e-3)" "unprognostic (2.75e-1)" "unprognostic (1.07e-2)" "unprognostic (7.87e-2)" "unprognostic (7.19e-2)" "unprognostic (2.46e-2)" "prognostic favorable (3.93e-4)" "unprognostic (1.08e-1)" "unprognostic (8.13e-2)" "prognostic unfavorable (8.57e-5)" "unprognostic (1.35e-1)" "unprognostic (3.91e-2)" "unprognostic (1.02e-1)" "unprognostic (1.50e-2)" 2.2 3.0 0.2 34.6 0.2 9.7 11.3 0.2 0.6 3.4 0.7 32.6 32.2 2.2 1.7 5.9 2.1 8.7 1.6 0.2 0.2 1.4 7.9 14.5 50.8 0.4 0.2 2.3 1.1 0.4 0.3 1.4 0.6 2.6 28.6 0.0 13.7 2.4 0.5 1.7 25.5 3.7 0.4 42.3 34.2 1.4 0.3 14.7 1.6 0.2 62.0 22.2 2.1 0.5 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 1.0 0.8 0.0 2.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 10.2 0.0 7.6 0.0 2.5 0.7 0.0 0.2 0.0 7.2 0.0 0.0 0.1 0.0 0.2 1.4 0.0 0.1 0.1 10.0 0.0 0.8 0.0 0.1 0.0 0.0 59.5 0.0 0.0 0.1 0.2 0.0 3.8 0.0 0.2 283.7 26.4 0.2 7.9 0.2 0.0 0.2 5.1 1.4 100.5 34.8 77.3 11.0 10.2 69.0 23.6 2.3 3.0 40.1 3.5 55.5 53.1 89.7 0.0 33.6 0.2 0.2 0.2 0.6 0.2 0.2 0.4 0.2 0.6 0.4 0.3 0.5 0.4 9.6 6.0 0.0 37.4 0.8 1.6 0.3 0.0 0.0 0.2 0.6 1.3 1.5 1.0 0.0 0.0 0.1 58.3 0.2 0.0 0.7 0.0 0.2 0.2 1.4 0.0 3.6 0.0 2.7 0.1 1.7 1.5 0.4 8.8 0.0 0.7 0.6 8.4 0.0 0.0 0.0 0.0 7.3 9.2 0.1 0.0 28.2 19.6 1.0 120.2 0.0 76.2 0.0 0.0 8.6 0.0 0.0 240.9 2.5 0.0 0.2 1.7 0.0 0.0 4.8 1.3 0.0 0.1 0.7 0.4 0.3 37.1 0.0 0.4 3.7 SLC11A2 "DCT1, DMT1, NRAMP2" ENSG00000110911 "Solute carrier family 11 member 2" P49281 12 50979401-51028566 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Respiratory ciliated cells: 109.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032139, HPA032140" Uncertain Supported Mitochondria No No "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "HPA032139: AB_10964213, HPA032140: AB_10962932" "unprognostic (4.40e-3)" "unprognostic (1.41e-2)" "unprognostic (1.50e-1)" "unprognostic (2.07e-3)" "unprognostic (2.35e-1)" "unprognostic (1.92e-1)" "unprognostic (2.09e-1)" "prognostic favorable (3.07e-6)" "unprognostic (1.06e-2)" "unprognostic (1.99e-2)" "unprognostic (1.15e-1)" "unprognostic (7.28e-2)" "unprognostic (2.29e-1)" "unprognostic (3.20e-2)" "unprognostic (2.61e-1)" "unprognostic (2.32e-2)" "unprognostic (2.24e-1)" 12.1 17.0 12.8 14.0 21.6 15.9 30.3 19.6 18.1 29.3 12.7 16.4 53.8 15.7 17.6 23.9 21.4 17.7 14.7 13.2 16.5 22.5 25.6 23.2 10.3 22.8 18.3 12.8 22.6 42.5 10.9 23.7 22.9 24.4 16.2 23.1 31.2 19.3 18.4 20.3 13.8 15.3 19.1 8.7 17.8 13.3 18.5 19.2 41.6 20.3 17.2 20.4 13.9 31.1 19.0 22.4 31.4 28.7 33.5 28.6 106.3 19.7 73.9 19.0 21.8 30.6 35.3 11.8 38.8 22.8 35.7 25.3 26.6 19.2 21.9 17.1 17.4 27.4 29.2 35.5 35.7 19.0 54.5 31.6 24.3 32.7 35.1 45.6 22.8 23.6 24.4 5.6 22.4 21.7 21.8 12.9 46.6 19.8 15.5 14.7 28.6 21.1 23.4 27.7 21.6 19.0 16.3 47.1 20.9 36.2 50.8 12.6 26.8 19.2 15.8 21.5 10.9 14.1 20.4 4.7 54.1 10.2 8.3 0.6 4.7 1.9 4.2 6.8 3.7 2.6 3.3 4.3 7.0 3.3 4.6 4.3 2.3 6.0 4.8 2.9 2.9 3.4 12.8 21.6 19.6 18.1 13.2 16.5 22.8 18.3 22.9 19.1 18.5 31.1 9.8 38.5 46.1 32.7 6.9 15.4 24.8 84.0 22.2 26.6 37.6 18.5 15.5 25.8 69.4 57.0 18.8 27.0 11.9 14.0 3.9 30.6 1.5 31.7 11.6 13.1 16.4 64.8 33.6 28.3 22.5 17.3 15.3 43.6 71.4 20.1 11.4 41.3 35.2 28.6 38.1 14.3 42.7 16.9 25.4 1.7 9.6 30.1 26.6 26.2 15.7 26.5 6.2 51.8 94.5 20.6 15.0 8.6 8.2 47.8 13.2 9.0 109.6 17.8 6.6 14.2 13.2 9.0 12.2 14.3 13.4 19.4 10.7 10.4 15.0 23.1 SLC16A5 "MCT5, MCT6" ENSG00000170190 "Solute carrier family 16 member 5" O15375 17 75087727-75106162 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 92.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Collecting duct cells: 88.3;Early spermatids: 42.2;Proximal enterocytes: 40.9;Respiratory ciliated cells: 45.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 13.2;neutrophil: 34.9" "Group enriched" "Detected in all" 6 "granulocytes: 34.9;monocytes: 13.2" "Cell line enhanced" "Detected in many" "A549: 65.9;OE19: 71.5;RPTEC TERT1: 68.8;RT4: 139.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 15: RT4 - Unknown function" "Cluster 45: Enterocytes - Digestion" "unprognostic (1.86e-2)" "unprognostic (1.18e-1)" "unprognostic (1.98e-1)" "unprognostic (2.51e-2)" "unprognostic (2.90e-2)" "unprognostic (2.72e-1)" "unprognostic (6.30e-2)" "unprognostic (2.55e-1)" "unprognostic (1.61e-1)" "unprognostic (5.26e-2)" "unprognostic (8.43e-3)" "unprognostic (8.07e-2)" "unprognostic (9.63e-2)" "unprognostic (3.53e-3)" "unprognostic (5.44e-2)" "unprognostic (1.07e-2)" "unprognostic (1.80e-1)" 6.5 1.4 1.1 4.8 1.1 8.7 7.2 1.2 1.2 9.4 5.0 15.2 34.0 8.5 4.4 11.2 16.1 8.2 13.9 1.0 1.7 92.8 3.3 24.6 3.4 2.2 2.2 8.1 4.7 4.6 2.7 10.8 1.7 15.0 10.3 0.1 7.9 12.5 9.4 15.9 24.9 4.2 1.9 10.6 26.0 6.5 2.4 1.9 14.3 4.6 3.9 18.5 11.1 1.8 14.2 65.9 1.2 0.1 3.2 4.2 22.0 7.7 19.8 7.7 5.4 16.9 39.6 0.0 9.2 24.1 1.0 39.7 3.2 10.8 2.9 0.0 0.2 5.1 33.5 8.9 14.9 0.0 0.2 10.1 12.8 7.8 0.1 0.1 15.8 0.7 1.1 0.2 0.5 2.3 0.5 7.1 5.0 71.5 0.2 1.6 0.0 0.5 68.8 139.8 0.0 0.4 19.4 4.5 9.7 11.0 32.0 7.1 5.7 0.1 0.1 0.5 0.1 0.2 0.0 0.0 0.3 4.3 4.3 4.1 13.2 3.5 0.5 5.0 0.3 1.4 0.6 0.1 3.9 0.3 1.4 0.6 34.9 1.0 2.6 0.1 0.8 4.4 1.1 1.1 1.2 1.2 1.0 1.7 2.2 2.2 1.7 1.9 2.4 1.8 4.4 38.5 34.5 0.0 0.9 2.5 7.7 10.1 6.2 0.0 5.6 6.1 5.5 7.2 23.5 88.3 0.0 18.5 0.5 17.1 5.9 6.4 42.2 9.7 1.5 5.0 6.7 0.4 0.2 1.3 3.7 3.7 11.7 6.1 7.0 3.9 12.8 0.4 6.5 0.0 0.3 13.2 4.1 8.5 1.8 31.8 0.6 5.5 7.2 3.7 7.9 0.2 3.1 0.0 0.1 1.0 23.8 0.0 0.2 11.3 40.9 1.9 45.4 0.0 0.0 0.8 2.1 0.3 1.5 3.6 1.3 19.6 1.4 1.1 11.8 25.5 SLC17A2 NPT3 ENSG00000112337 "Solute carrier family 17 member 2" O00624 6 25912754-25930691 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 165 "liver: 79.5" "Cell type enriched" "Detected in some" 20 "Hepatocytes: 30.9" "Cancer enriched" "Detected in some" 8 "liver cancer: 14.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 21 "Hep G2: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA038270 Uncertain NA NA "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA038270: AB_10672511" "prognostic favorable (8.54e-4)" "unprognostic (1.90e-2)" "unprognostic (4.14e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 79.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 30.9 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLC1A1 "EAAC1, EAAT3" ENSG00000106688 "Solute carrier family 1 member 1" P43005 9 4490468-4587469 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 45.0;intestine: 64.7;kidney: 51.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 163.5;Glandular and luminal cells: 98.7;Hepatocytes: 68.4;Microglial cells: 67.5;Oligodendrocyte precursor cells: 161.4;Proximal enterocytes: 110.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 29.1;HDLM-2: 70.9;HUVEC TERT2: 32.5;RPTEC TERT1: 66.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062356 Enhanced NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "HPA062356: " "unprognostic (1.28e-2)" "unprognostic (2.37e-2)" "unprognostic (6.83e-3)" "unprognostic (3.07e-3)" "unprognostic (2.04e-2)" "unprognostic (1.51e-1)" "unprognostic (1.07e-1)" "unprognostic (4.28e-2)" "unprognostic (1.58e-1)" "unprognostic (2.71e-1)" "unprognostic (1.35e-2)" "unprognostic (1.25e-2)" "prognostic favorable (2.86e-8)" "unprognostic (2.68e-1)" "unprognostic (9.49e-2)" "unprognostic (7.78e-2)" "unprognostic (2.64e-1)" 4.6 1.7 13.2 2.3 15.4 0.1 4.1 9.5 14.8 5.8 12.9 12.4 34.8 3.7 45.0 2.3 2.6 25.5 2.8 16.5 12.6 51.0 41.2 20.9 2.6 10.8 13.0 0.6 2.1 0.3 6.8 8.1 13.6 6.3 10.2 6.0 4.8 3.2 1.4 1.5 64.7 3.2 10.9 0.4 5.2 0.8 13.9 0.4 29.5 1.3 8.2 5.6 1.5 10.1 0.1 2.0 1.6 9.5 24.3 29.1 8.3 10.4 21.4 3.2 3.1 17.2 0.5 13.7 0.6 5.4 3.9 0.0 3.6 5.7 2.9 70.9 4.5 0.0 13.6 0.1 0.8 0.9 0.0 2.0 0.2 12.1 0.0 1.6 32.5 0.2 0.0 0.0 2.2 0.3 0.0 0.3 4.2 10.5 1.8 0.0 0.0 0.2 66.4 6.1 2.2 2.0 0.8 3.8 0.0 7.7 1.4 0.5 17.6 4.9 0.4 9.5 3.0 0.1 0.1 0.0 23.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 13.2 15.4 9.5 14.8 16.5 12.6 10.8 13.0 13.6 10.9 13.9 10.1 12.2 163.5 3.2 4.2 0.4 0.0 1.1 0.6 4.6 3.9 2.0 0.8 2.3 28.6 6.1 0.0 0.0 0.1 0.0 52.4 3.9 8.1 4.3 10.7 13.3 10.6 0.0 0.0 48.4 0.8 0.0 1.8 2.0 98.7 0.0 0.6 2.5 68.4 0.1 0.0 50.3 10.1 0.0 1.3 0.3 11.2 0.3 1.1 0.0 67.5 0.0 0.8 0.0 161.4 3.5 9.3 10.6 0.0 0.0 2.4 110.6 43.1 3.3 1.1 0.0 0.5 3.1 0.1 0.2 1.0 0.6 0.1 1.4 0.4 8.5 1.8 SLC22A24 "MGC34821, NET46" ENSG00000197658 "Solute carrier family 22 member 24" Q8N4F4 11 63079940-63144221 "Predicted membrane proteins" "Ion transport, Lipid metabolism, Steroid metabolism, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 1.1;kidney: 4.4" "Group enriched" "Detected in some" 5 "Excitatory neurons: 5.9;Proximal tubular cells: 11.8" "Cancer enriched" "Detected in single" 11 "renal cancer: 0.5" "Region enhanced" "Detected in single" "cerebral cortex: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045015 Uncertain NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA045015: AB_2679183" "unprognostic (5.72e-3)" "unprognostic (1.80e-7)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 4.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 1.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLC31A1 "COPT1, CTR1, hCTR1" ENSG00000136868 "Solute carrier family 31 member 1" O15431 9 113221544-113264492 "Metabolic proteins, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 107.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 97.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 20.9;intermediate monocyte: 26.8;myeloid DC: 16.3;neutrophil: 8.2;non-classical monocyte: 31.0" "Group enriched" "Detected in all" 4 "dendritic cells: 16.3;granulocytes: 8.2;monocytes: 31.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013810 Approved NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "HPA013810: AB_1857095" "unprognostic (1.22e-2)" "unprognostic (1.74e-1)" "unprognostic (4.29e-2)" "unprognostic (5.48e-3)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" "unprognostic (6.99e-3)" "unprognostic (7.58e-2)" "unprognostic (2.30e-1)" "unprognostic (2.51e-1)" "unprognostic (7.18e-2)" "unprognostic (3.61e-1)" "prognostic favorable (2.20e-6)" "unprognostic (1.22e-2)" "unprognostic (2.18e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (2.51e-2)" 11.5 23.9 5.7 11.1 5.8 11.7 12.7 6.6 6.5 20.7 26.3 16.3 45.1 7.2 13.7 12.0 6.5 9.6 7.4 6.9 6.6 28.7 107.6 17.7 6.3 7.2 6.9 4.9 19.1 15.2 5.8 13.5 11.7 21.3 17.0 7.1 66.5 12.8 3.5 18.5 37.4 10.0 6.8 7.6 19.4 6.4 7.0 5.5 10.9 5.8 12.4 14.3 6.5 6.5 22.1 23.4 18.7 41.4 42.0 29.8 68.8 38.3 58.0 26.0 30.1 33.5 18.8 17.2 15.2 33.0 32.9 53.3 35.8 21.8 29.0 15.2 19.9 14.2 18.7 37.6 102.3 26.1 20.6 36.1 48.3 33.6 54.6 17.4 24.0 19.6 32.8 30.9 24.8 23.6 17.9 13.2 30.4 84.2 26.0 18.3 49.1 17.2 23.6 27.2 17.7 23.1 37.0 73.0 101.5 26.2 37.2 22.0 22.3 19.3 11.9 39.1 23.2 18.5 40.5 23.6 31.9 24.2 23.1 3.0 20.9 2.5 2.3 26.8 3.2 1.7 1.6 2.4 16.3 1.5 1.8 1.7 8.2 4.4 31.0 2.3 1.8 7.6 5.7 5.8 6.6 6.5 6.9 6.6 7.2 6.9 11.7 6.8 7.0 6.5 8.0 35.3 33.5 7.5 6.6 15.2 10.6 27.4 10.2 12.6 21.4 14.9 7.4 21.5 50.8 5.5 33.3 16.5 6.9 40.2 9.8 18.3 0.3 16.2 15.6 11.6 9.0 25.4 16.8 27.2 24.1 16.0 15.3 14.5 5.1 11.4 11.4 97.1 43.4 6.7 17.0 18.9 42.7 39.4 19.9 0.9 6.2 40.3 12.4 20.6 21.8 12.2 4.1 16.1 12.3 22.3 11.1 7.2 16.1 28.9 61.7 24.7 30.1 11.2 6.6 8.4 15.2 24.4 30.7 15.1 15.8 22.4 5.5 15.2 19.9 22.6 SLC35D1 "KIAA0260, UGTREL7" ENSG00000116704 "Solute carrier family 35 member D1" Q9NTN3 1 66999350-67054148 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" Dwarfism "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 74.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 75.6;Early spermatids: 73.5;Hepatocytes: 114.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (6.91e-2)" "unprognostic (3.69e-2)" "unprognostic (1.20e-3)" "prognostic unfavorable (7.47e-4)" "unprognostic (2.63e-1)" "unprognostic (6.53e-2)" "unprognostic (2.49e-2)" "prognostic unfavorable (6.55e-4)" "unprognostic (2.12e-3)" "unprognostic (6.39e-2)" "unprognostic (6.75e-2)" "unprognostic (2.07e-1)" "unprognostic (7.65e-2)" "unprognostic (1.55e-1)" "unprognostic (2.43e-1)" "unprognostic (4.08e-3)" "unprognostic (3.20e-1)" 4.9 6.6 4.0 7.8 4.6 8.9 5.2 4.1 4.2 7.6 9.9 26.0 15.9 5.7 4.9 5.3 5.0 6.4 3.7 3.8 4.2 12.5 74.7 3.7 7.5 4.7 6.1 7.8 7.5 8.1 5.6 9.5 4.8 7.2 26.8 12.3 4.4 5.7 7.5 9.8 16.3 6.9 4.0 4.2 12.9 6.2 5.8 10.1 6.4 5.0 8.6 7.3 6.8 7.0 8.3 4.7 14.2 12.0 14.4 16.6 16.8 18.4 24.1 13.1 9.1 10.2 2.0 25.7 7.9 14.6 15.4 12.5 9.9 11.6 16.4 25.8 4.6 19.2 9.8 20.2 12.1 22.0 12.2 16.3 25.4 15.4 10.9 21.0 5.1 10.6 11.8 13.3 32.0 2.8 13.6 6.8 5.9 22.5 6.4 10.4 29.3 2.9 6.0 15.6 1.7 6.3 27.8 8.5 11.9 7.9 7.0 16.2 5.6 24.2 5.7 15.0 17.9 27.6 15.4 14.1 17.2 3.3 10.4 8.5 0.9 2.6 2.0 0.7 2.4 1.3 1.5 1.6 1.1 0.9 2.1 2.0 0.2 3.5 1.7 0.6 2.8 0.9 4.0 4.6 4.1 4.2 3.8 4.2 4.7 6.1 4.8 4.0 5.8 7.0 4.9 6.4 2.2 34.6 12.8 5.5 5.9 9.4 13.1 6.9 7.5 4.8 3.1 20.0 4.6 5.5 12.5 40.5 18.3 75.6 0.0 3.1 73.5 6.3 10.9 4.3 15.0 9.1 22.8 9.6 5.7 8.3 14.8 8.7 4.5 13.2 7.5 114.3 6.9 6.7 28.2 18.9 2.0 8.8 4.6 13.7 6.2 5.5 1.8 23.4 3.1 17.8 9.2 37.7 51.2 8.3 20.8 4.5 9.3 5.8 24.9 10.6 7.5 9.4 0.0 8.6 7.5 7.7 6.4 8.2 7.7 16.3 12.8 11.3 21.7 8.8 SLC35E4 ENSG00000100036 "Solute carrier family 35 member E4" Q6ICL7 22 30635781-30669016 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.9" "Group enriched" "Detected in many" 4 "Early spermatids: 122.2;Late spermatids: 108.6;Spermatocytes: 55.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HDLM-2: 22.8;U-2197: 21.0;U-87 MG: 22.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049558 Approved Approved Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA049558: AB_2680817" "unprognostic (2.09e-1)" "unprognostic (1.88e-1)" "unprognostic (2.05e-1)" "unprognostic (1.01e-2)" "unprognostic (4.99e-2)" "unprognostic (2.04e-1)" "unprognostic (3.03e-4)" "unprognostic (5.71e-2)" "unprognostic (7.85e-2)" "unprognostic (1.76e-1)" "unprognostic (1.05e-2)" "unprognostic (2.39e-2)" "unprognostic (3.45e-7)" "unprognostic (2.77e-3)" "unprognostic (1.77e-1)" "unprognostic (2.24e-2)" "unprognostic (8.05e-3)" 2.6 1.8 3.5 1.4 5.0 1.5 2.2 2.9 6.7 2.6 0.4 3.2 1.0 3.5 1.3 2.8 2.5 1.1 3.4 4.1 3.5 2.4 0.5 2.0 0.8 4.7 4.5 1.9 1.7 1.7 2.3 0.4 4.7 2.3 1.7 1.5 2.1 1.3 11.1 5.3 1.8 1.4 1.9 1.9 3.4 22.9 4.5 0.3 1.6 2.8 0.5 3.1 2.8 7.3 10.0 4.3 1.6 3.2 4.3 10.9 0.9 6.4 5.6 4.3 4.0 0.3 2.6 0.7 3.4 6.6 6.1 6.2 2.8 3.7 2.2 22.8 3.1 0.1 3.3 0.3 6.1 0.4 2.7 3.5 1.6 17.3 5.4 6.8 14.9 0.8 0.9 2.8 6.8 2.8 0.4 1.9 1.9 2.9 16.2 1.8 3.2 0.3 2.0 0.8 8.7 3.4 6.6 2.8 3.2 0.7 2.0 0.7 20.0 18.2 5.8 21.0 6.2 0.8 0.9 0.3 22.3 0.3 4.9 0.6 0.6 0.1 0.2 0.8 0.4 0.0 0.6 0.9 1.1 0.1 0.5 0.5 0.2 0.6 0.7 0.3 0.7 0.3 3.5 5.0 2.9 6.7 4.1 3.5 4.7 4.5 4.7 1.9 4.5 7.3 5.7 0.0 1.5 2.6 2.7 14.5 2.5 1.9 8.0 10.6 2.0 3.7 1.9 0.0 1.2 1.8 22.9 0.1 4.8 5.4 0.0 3.4 122.2 6.0 4.9 9.1 2.4 0.8 4.2 2.3 0.5 3.7 2.6 2.0 1.3 4.1 4.2 0.3 1.8 11.8 4.9 4.4 2.0 1.2 7.7 108.6 3.4 8.0 3.6 4.7 2.5 17.2 1.0 2.5 9.2 2.5 11.1 3.8 3.1 1.7 1.2 0.4 5.7 10.5 0.0 3.9 5.0 55.1 3.8 4.2 19.0 0.1 4.9 2.4 5.0 2.1 SLC37A2 FLJ00171 ENSG00000134955 "Solute carrier family 37 member 2" Q8TED4 11 125063302-125090516 "Predicted membrane proteins, Transporters" "Antiport, Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 78.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 13.4;Hofbauer cells: 36.5;Kupffer cells: 22.0;Macrophages: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 12.3;intermediate monocyte: 14.1;myeloid DC: 5.5;non-classical monocyte: 19.2" "Group enriched" "Detected in many" 9 "dendritic cells: 5.5;monocytes: 19.2" "Cell line enhanced" "Detected in many" "A-431: 33.8;CAPAN-2: 70.3;hTCEpi: 34.9;hTERT-HME1: 64.8;U-138 MG: 47.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014948 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "HPA014948: AB_2190374" "unprognostic (8.47e-2)" "unprognostic (4.85e-1)" "unprognostic (9.64e-2)" "unprognostic (2.91e-2)" "unprognostic (7.88e-2)" "unprognostic (2.84e-1)" "unprognostic (5.47e-2)" "unprognostic (1.68e-1)" "unprognostic (2.06e-2)" "unprognostic (1.30e-1)" "unprognostic (2.15e-2)" "unprognostic (3.11e-1)" "unprognostic (6.61e-2)" "unprognostic (1.94e-3)" "unprognostic (1.66e-3)" "unprognostic (7.01e-2)" "unprognostic (3.24e-2)" 4.2 24.2 1.7 16.9 2.6 1.4 4.6 2.4 3.7 2.3 2.1 8.0 9.1 1.0 1.3 13.4 1.2 5.1 1.5 1.9 2.3 0.7 5.9 5.9 5.7 4.3 2.7 1.0 1.2 1.1 0.2 7.4 3.8 2.6 10.2 0.5 78.8 1.4 0.6 20.9 7.7 3.1 3.2 15.8 2.1 1.6 5.2 2.1 0.6 0.9 5.1 11.9 7.7 7.3 33.8 0.1 1.0 0.4 0.6 0.8 0.6 1.6 2.8 1.0 2.5 0.2 70.3 0.4 9.4 0.4 2.5 21.0 0.4 20.9 3.8 0.9 0.6 6.6 1.6 2.4 0.1 0.3 0.9 0.7 34.9 2.6 64.8 2.7 1.7 1.3 0.5 2.2 3.1 0.3 0.3 4.6 1.9 0.2 1.0 0.4 2.7 0.8 1.0 17.6 0.3 0.3 4.8 2.9 2.6 0.5 0.3 1.8 3.7 47.2 1.9 0.7 1.6 1.8 1.5 1.1 1.7 2.4 4.1 0.2 12.3 0.0 0.0 14.1 0.0 0.4 0.0 0.1 5.5 0.1 0.1 0.1 1.3 0.0 19.2 0.2 0.0 5.4 1.7 2.6 2.4 3.7 1.9 2.3 4.3 2.7 3.8 3.2 5.2 7.3 0.7 0.0 0.6 0.3 3.8 0.3 1.4 0.5 1.2 1.5 1.4 1.1 1.1 1.5 1.6 0.0 2.1 0.6 0.7 13.4 0.0 0.1 1.6 1.9 1.4 1.3 0.0 2.7 0.3 0.0 0.8 0.5 0.0 4.9 2.5 0.4 1.8 0.3 36.5 0.0 0.3 0.1 0.0 22.0 1.4 2.2 0.9 22.7 0.0 8.4 7.3 0.3 3.1 1.0 0.2 0.1 3.3 1.2 1.7 1.0 0.0 0.1 0.2 0.8 0.0 0.8 0.6 2.7 1.1 5.7 0.9 3.4 1.2 0.4 0.1 3.2 SLC38A4 "ATA3, NAT3, PAAT" ENSG00000139209 "Solute carrier family 38 member 4" Q969I6 12 46764761-46832408 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 60 "liver: 609.9" "Cell type enriched" "Detected in some" 25 "Hepatocytes: 289.5" "Cancer enriched" "Detected in many" 14 "liver cancer: 61.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 17.7;LHCN-M2: 43.2;RH-30: 14.6;RT4: 86.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 62: Liver - Hemostasis" "Cluster 15: RT4 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (3.81e-2)" "unprognostic (7.46e-3)" "unprognostic (5.22e-3)" "unprognostic (1.75e-2)" "unprognostic (3.12e-1)" "unprognostic (1.11e-1)" "prognostic favorable (5.37e-4)" "unprognostic (3.06e-2)" "unprognostic (2.57e-3)" "unprognostic (1.75e-2)" "unprognostic (1.95e-1)" "unprognostic (6.06e-2)" "unprognostic (2.84e-2)" "unprognostic (1.89e-2)" "unprognostic (8.28e-2)" "unprognostic (6.31e-3)" "unprognostic (2.21e-2)" 0.8 1.1 0.2 0.3 0.2 0.0 1.2 0.1 0.4 0.5 0.5 5.1 0.4 2.2 0.2 1.7 0.9 0.3 0.3 0.1 0.6 4.4 609.9 0.3 0.2 0.2 0.3 0.2 6.6 0.2 0.1 2.2 0.1 1.3 1.3 0.1 0.8 0.5 10.2 2.6 0.5 5.4 0.2 1.2 0.2 0.3 0.7 1.4 0.3 2.6 0.8 2.0 0.2 0.3 0.0 0.0 0.1 0.0 17.7 2.2 3.4 2.3 5.6 2.0 1.8 1.1 4.3 0.0 3.5 7.8 0.0 1.0 0.0 0.6 1.7 0.0 0.0 0.1 0.0 0.2 0.7 0.5 0.0 4.2 0.1 0.1 1.4 0.1 0.0 0.0 0.2 0.0 43.2 0.0 0.1 0.0 1.3 0.0 0.0 0.0 14.6 0.0 0.0 86.0 0.3 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.2 0.5 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.4 0.1 0.6 0.2 0.3 0.1 0.2 0.7 0.3 0.1 0.0 0.0 2.6 0.5 0.8 0.0 2.2 3.4 0.0 0.1 0.0 1.5 11.5 0.2 1.8 0.0 2.5 0.0 1.9 0.0 0.0 0.2 0.4 0.2 1.2 0.0 5.3 0.6 0.0 0.7 1.2 0.0 0.2 0.0 1.6 3.9 289.5 0.5 0.0 2.2 0.4 2.0 6.7 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.2 1.2 0.0 0.0 0.7 0.3 0.4 0.2 0.0 0.0 0.3 0.2 0.0 0.1 2.8 0.6 0.8 0.4 2.7 1.3 0.1 SLC39A13 FLJ25785 ENSG00000165915 "Solute carrier family 39 member 13" Q96H72 11 47407132-47416496 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 13 "Early spermatids: 298.2;Late spermatids: 905.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043971 Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "HPA043971: AB_10959744" "unprognostic (7.84e-2)" "unprognostic (1.02e-2)" "prognostic unfavorable (2.60e-4)" "unprognostic (1.18e-1)" "unprognostic (8.56e-3)" "unprognostic (3.81e-2)" "unprognostic (7.44e-3)" "unprognostic (1.36e-1)" "unprognostic (5.40e-2)" "prognostic unfavorable (2.73e-5)" "unprognostic (1.39e-2)" "unprognostic (2.04e-2)" "prognostic favorable (1.96e-4)" "unprognostic (3.16e-1)" "unprognostic (1.73e-1)" "unprognostic (8.61e-2)" "unprognostic (4.12e-1)" 40.9 42.4 28.3 24.2 31.4 8.3 37.5 30.6 36.3 51.1 30.4 53.4 14.0 77.9 8.8 21.8 48.1 20.2 59.5 26.0 27.3 80.4 26.7 61.4 18.2 33.0 29.7 50.9 42.3 27.2 51.3 40.6 30.4 52.7 6.8 11.0 31.3 26.2 31.4 32.4 31.8 26.6 26.8 36.5 41.2 73.4 35.0 12.3 46.8 12.6 8.7 45.6 37.4 28.5 23.3 20.4 23.5 26.7 56.3 78.2 6.8 89.7 66.2 50.4 57.0 8.1 15.7 8.8 22.9 69.6 49.6 38.3 7.1 61.7 13.9 25.7 25.9 4.7 52.7 16.7 84.3 8.1 11.0 65.4 43.4 31.9 26.1 62.9 53.4 16.9 4.5 19.6 54.8 20.7 17.4 11.5 11.0 19.8 28.2 20.6 33.6 8.9 86.1 11.1 19.9 37.0 26.9 49.1 26.2 8.7 32.8 11.7 76.0 76.6 34.6 88.1 42.7 14.9 5.2 4.1 85.2 11.2 57.3 2.1 3.6 3.2 12.4 13.3 8.5 4.1 8.2 8.9 4.6 5.1 7.5 6.4 6.6 7.4 15.3 4.9 4.5 5.9 28.3 31.4 30.6 36.3 26.0 27.3 33.0 29.7 30.4 26.8 35.0 28.5 20.0 9.6 6.4 18.6 6.7 18.2 18.3 23.0 17.1 24.0 11.5 15.6 18.3 15.7 8.0 29.5 12.5 11.1 11.6 3.4 9.8 32.9 298.2 6.5 20.3 20.9 9.6 4.4 9.6 20.7 16.4 37.8 6.6 13.1 5.7 15.4 21.8 6.2 18.9 32.0 11.7 7.9 14.2 5.3 12.2 905.5 32.9 9.3 19.6 4.7 26.6 16.7 11.3 8.0 10.1 35.5 8.3 40.3 8.1 23.5 8.2 8.8 4.5 17.0 46.0 16.1 36.2 12.7 6.4 2.4 4.1 19.6 9.6 36.7 5.7 8.3 SLC39A9 FLJ11274 ENSG00000029364 "Solute carrier family 39 member 9" Q9NUM3 14 69398015-69462390 "Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007921, HPA075390" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 27: Mucus-secreting cells - Mucin production" "Endoplasmic reticulum" "HPA007921: AB_1080007, HPA075390: AB_2686748" "unprognostic (2.37e-1)" "unprognostic (9.29e-2)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (4.35e-2)" "unprognostic (1.10e-1)" "unprognostic (5.50e-2)" "unprognostic (1.71e-1)" "unprognostic (2.49e-1)" "unprognostic (2.75e-1)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "prognostic favorable (1.05e-6)" "unprognostic (1.20e-1)" "unprognostic (1.83e-1)" "unprognostic (1.09e-2)" "unprognostic (2.16e-2)" 15.2 21.6 17.3 12.1 17.5 10.7 24.4 17.7 24.6 18.2 20.9 20.3 21.5 14.8 25.6 23.1 15.6 14.3 12.2 17.4 18.9 29.8 43.0 15.6 12.7 17.0 17.3 13.7 28.5 26.4 22.8 17.7 17.0 19.0 21.5 12.7 33.8 15.1 7.9 18.3 19.4 15.5 18.7 16.0 21.8 8.9 18.3 18.0 22.2 11.6 17.8 15.3 15.3 20.1 55.0 46.3 26.9 28.7 46.2 34.6 25.1 31.9 40.2 30.7 34.8 35.4 49.7 49.3 23.8 39.8 14.2 45.3 30.9 30.5 37.4 31.9 17.0 28.9 23.0 24.8 36.0 20.9 38.1 30.3 50.3 27.1 40.5 30.6 30.8 38.1 22.2 44.2 32.5 33.6 33.0 26.1 20.9 47.7 31.2 32.8 37.6 30.3 40.9 56.1 28.3 46.1 32.2 55.1 22.2 20.2 76.9 37.8 30.4 50.8 36.2 22.1 24.6 48.8 27.4 36.6 47.1 25.4 42.0 11.2 10.3 9.4 7.9 9.7 8.1 6.9 6.8 7.7 11.3 4.8 6.7 7.0 8.7 6.8 9.4 5.9 5.5 6.8 17.3 17.5 17.7 24.6 17.4 18.9 17.0 17.3 17.0 18.7 18.3 20.1 13.3 19.2 12.6 37.9 13.4 12.1 8.0 19.2 17.1 8.4 27.7 14.1 7.9 18.6 18.0 16.5 6.2 14.1 7.3 42.8 5.9 15.0 16.2 16.0 16.1 17.0 29.4 15.4 31.0 25.1 17.3 14.3 22.4 17.8 12.0 13.8 22.1 67.7 15.9 10.1 30.9 30.3 14.2 24.5 8.7 22.4 13.1 13.8 7.2 24.4 16.4 9.5 12.3 30.2 37.0 28.6 22.4 12.8 18.6 18.7 34.6 15.8 24.6 11.2 6.6 12.6 12.0 13.9 9.2 18.3 12.5 17.8 9.2 14.2 25.7 20.2 SLC44A1 "CD92, CDW92, CHTL1, CTL1" ENSG00000070214 "Solute carrier family 44 member 1" Q8WWI5 9 105244622-105439171 "CD markers, Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 284.9" "Cell type enriched" "Detected in all" 8 "Oligodendrocytes: 2444.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "ASC diff: 285.9;ASC TERT1: 224.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064714, HPA074007" Enhanced Supported Nucleoplasm,Mitochondria NA NA 99000 "Cluster 24: B-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria Nucleoplasm "HPA064714: AB_2685334, HPA074007: " "unprognostic (3.49e-1)" "unprognostic (2.25e-1)" "unprognostic (1.27e-1)" "unprognostic (6.54e-3)" "unprognostic (4.77e-2)" "unprognostic (1.74e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (4.49e-4)" "unprognostic (2.48e-1)" "unprognostic (1.95e-1)" "unprognostic (1.64e-3)" "unprognostic (6.20e-2)" "prognostic favorable (1.85e-4)" "unprognostic (2.13e-1)" "unprognostic (2.07e-1)" "unprognostic (1.33e-1)" "unprognostic (2.07e-2)" 16.9 13.3 112.9 12.9 204.4 11.4 26.2 166.7 138.7 16.7 79.4 50.2 22.6 15.9 32.4 18.4 15.2 20.2 12.7 116.2 136.1 21.8 38.0 18.4 9.7 204.3 167.7 14.1 15.1 23.2 5.3 23.3 205.5 11.8 49.0 14.1 9.6 25.0 9.4 21.5 27.0 17.3 161.1 9.5 35.2 3.5 150.8 13.6 43.6 20.2 15.5 21.8 15.6 284.9 29.0 23.8 6.4 7.9 285.9 224.1 20.3 23.9 61.7 15.1 20.2 25.6 74.8 38.4 12.0 90.2 17.1 56.1 19.3 34.4 25.7 34.0 15.7 47.8 15.8 32.0 19.3 9.6 23.7 125.3 27.6 29.0 26.1 38.8 48.6 19.7 1.4 77.1 17.3 40.8 38.8 10.9 35.9 51.1 22.9 8.0 24.7 29.3 20.9 66.6 30.6 12.0 33.4 36.5 33.3 37.8 36.2 28.7 41.9 15.1 13.5 16.5 17.7 59.1 41.7 28.4 29.2 20.6 20.2 1.7 3.3 0.7 0.7 1.2 0.4 1.1 0.7 0.4 2.2 2.0 0.8 0.3 0.5 5.3 0.7 0.8 0.8 0.9 112.9 204.4 166.7 138.7 116.2 136.1 204.3 167.7 205.5 161.1 150.8 284.9 48.6 35.3 26.5 83.2 22.2 70.6 36.0 28.3 75.1 10.3 76.9 27.2 10.1 67.2 19.9 106.7 235.6 53.3 7.6 296.5 3.9 17.5 2.9 59.2 40.3 45.2 157.2 20.4 174.2 36.5 12.1 64.0 84.1 175.2 100.1 16.7 48.9 170.0 21.3 6.7 108.1 160.0 14.2 46.5 46.5 6.1 110.0 48.6 74.7 81.5 91.0 9.0 13.4 257.3 2444.2 36.9 161.2 79.7 162.9 23.8 95.4 27.1 31.4 53.3 39.5 43.8 34.9 2.3 4.4 86.9 74.3 70.6 20.3 12.1 199.1 34.8 SLC4A11 "BTR1, CDPD1, CHED2, dJ794I6.2, FECD4, NaBC1" ENSG00000088836 "Solute carrier family 4 member 11" Q8NBS3 20 3227417-3239559 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Symport, Transport" "Corneal dystrophy, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 51.3;salivary gland: 54.0;thyroid gland: 60.9" "Cell type enhanced" "Detected in many" "Club cells: 25.5;Collecting duct cells: 112.2;Ionocytes: 79.3;Respiratory ciliated cells: 48.1;Sertoli cells: 26.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 70.6;Hep G2: 43.0;RT4: 30.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA018120, HPA058377" Uncertain Uncertain Nucleoplasm,Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm Vesicles "HPA018120: AB_1857186, HPA058377: " "unprognostic (2.33e-1)" "prognostic favorable (9.03e-4)" "unprognostic (1.18e-2)" "unprognostic (3.05e-2)" "unprognostic (1.00e-1)" "unprognostic (6.52e-2)" "unprognostic (9.66e-3)" "unprognostic (3.73e-2)" "unprognostic (3.10e-3)" "unprognostic (1.52e-3)" "unprognostic (2.94e-1)" "unprognostic (2.64e-1)" "prognostic favorable (6.21e-6)" "unprognostic (7.37e-2)" "unprognostic (4.30e-1)" "unprognostic (2.33e-1)" "unprognostic (6.89e-3)" 2.4 6.9 4.5 0.7 3.5 0.4 3.4 2.3 3.1 10.9 5.6 0.4 0.1 0.5 2.6 16.5 1.7 1.1 0.8 2.9 1.4 51.3 0.2 2.0 1.4 2.0 2.3 0.2 0.5 0.6 4.3 0.2 2.6 5.4 0.3 0.4 54.0 7.0 5.2 12.8 0.6 0.3 0.8 0.7 2.5 5.9 4.3 1.0 60.9 0.1 1.8 3.4 5.8 1.9 11.0 15.5 1.8 7.9 5.1 1.3 21.1 5.4 3.4 2.8 1.6 1.1 14.1 0.0 6.1 1.9 6.6 70.6 8.3 16.8 0.5 0.1 3.2 0.7 7.5 43.0 3.2 4.0 13.6 0.7 6.8 3.4 3.2 2.3 7.0 9.8 1.6 9.7 2.9 7.2 0.5 0.4 12.1 13.6 20.7 2.6 10.3 3.5 16.9 30.7 0.9 4.9 2.7 17.5 0.3 5.4 6.7 7.0 12.1 2.1 7.0 0.5 2.7 0.4 0.6 0.1 0.1 2.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 4.5 3.5 2.3 3.1 2.9 1.4 2.0 2.3 2.6 0.8 4.3 1.9 0.8 0.0 0.0 1.6 0.0 0.8 2.2 16.3 8.0 0.2 4.9 4.4 1.1 0.0 25.5 112.2 0.0 0.1 0.6 0.8 0.0 0.7 5.8 2.3 0.6 0.7 0.0 0.0 0.3 0.5 0.1 0.3 5.1 4.2 0.0 0.2 1.1 0.0 0.4 0.0 0.1 0.2 79.3 0.3 0.0 2.2 0.0 0.5 0.0 0.0 0.6 0.1 0.0 0.0 0.3 3.0 1.3 0.4 0.0 3.7 0.0 0.5 48.1 0.2 26.3 0.6 5.8 3.0 4.7 3.3 0.4 0.0 0.2 0.1 0.2 5.7 SLC7A11 xCT ENSG00000151012 "Solute carrier family 7 member 11" Q9UPY5 4 138164097-138242349 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.5" "Cell type enhanced" "Detected in many" "Astrocytes: 368.6;Microglial cells: 148.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "hTCEpi: 84.2;TIME: 95.2;WM-115: 138.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064215 Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "HPA064215: AB_2685213" "unprognostic (3.55e-3)" "unprognostic (4.64e-3)" "unprognostic (2.43e-2)" "unprognostic (7.18e-3)" "unprognostic (2.59e-1)" "unprognostic (8.80e-3)" "unprognostic (2.07e-8)" "unprognostic (1.98e-2)" "unprognostic (1.09e-2)" "prognostic favorable (1.77e-4)" "unprognostic (1.90e-2)" "unprognostic (4.07e-2)" "unprognostic (2.22e-8)" "unprognostic (3.81e-2)" "unprognostic (3.76e-2)" "unprognostic (2.29e-2)" "unprognostic (1.54e-2)" 0.2 0.1 18.8 2.2 17.5 1.0 0.4 16.5 16.5 0.9 7.2 0.7 0.4 0.3 6.7 2.6 4.5 1.6 1.7 16.2 26.5 0.1 0.2 1.7 0.4 24.3 22.8 0.5 2.7 0.3 0.8 0.7 19.0 0.6 1.0 4.2 0.7 0.1 0.0 0.6 0.4 0.1 19.8 0.4 4.9 0.8 20.1 0.3 4.6 0.0 0.8 2.7 0.5 20.1 5.2 42.1 18.4 14.5 3.9 5.0 5.1 23.2 15.9 5.2 11.8 4.7 17.7 9.7 29.5 80.8 27.6 6.7 10.0 19.8 21.7 18.5 2.1 6.9 37.7 10.7 59.6 18.1 6.3 11.9 84.2 14.6 64.6 7.6 65.1 9.6 9.5 24.4 27.3 3.7 2.5 1.7 3.6 25.1 11.9 2.8 6.1 11.5 3.1 20.1 7.6 1.5 10.1 2.9 35.4 3.9 4.4 38.1 95.2 6.7 18.8 10.2 18.3 20.5 10.3 9.7 11.4 9.7 138.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 18.8 17.5 16.5 16.5 16.2 26.5 24.3 22.8 19.0 19.8 20.1 20.1 0.5 0.0 8.4 368.6 2.5 4.6 7.5 8.8 1.8 7.3 2.2 1.3 5.4 1.5 8.1 0.0 2.1 3.6 28.5 7.9 0.0 4.4 3.2 3.2 2.3 27.8 27.0 0.8 12.5 25.1 0.7 5.7 65.2 18.3 4.5 1.0 2.9 0.4 0.6 1.7 7.3 19.8 22.4 0.3 63.5 0.8 2.5 18.3 5.4 148.9 51.7 47.9 0.0 12.1 8.6 30.4 1.5 2.2 4.1 58.5 0.4 0.1 7.3 2.0 0.0 2.1 4.0 1.1 0.7 1.9 3.1 1.1 0.9 7.0 4.2 37.6 SLC7A4 "CAT-4, HCAT3, VH" ENSG00000099960 "Solute carrier family 7 member 4" O43246 22 21028718-21032840 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 15.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 21.2;Endometrial ciliated cells: 16.4;Glandular and luminal cells: 32.0;Intestinal goblet cells: 8.9;Ionocytes: 12.2;Syncytiotrophoblasts: 10.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 21 "BEWO: 140.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA031023 Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" "HPA031023: AB_10669669" "unprognostic (1.02e-3)" "unprognostic (4.34e-2)" "unprognostic (6.75e-2)" "unprognostic (1.27e-1)" "unprognostic (3.82e-2)" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (3.91e-2)" "unprognostic (3.68e-2)" "unprognostic (2.51e-2)" "unprognostic (2.58e-2)" "unprognostic (1.21e-3)" "unprognostic (9.69e-2)" "unprognostic (2.87e-1)" "unprognostic (1.62e-1)" "unprognostic (1.32e-2)" "unprognostic (4.00e-3)" 2.7 2.6 3.1 0.2 2.6 0.0 1.0 3.8 2.8 1.5 4.5 1.1 1.0 1.0 0.3 5.6 1.1 1.3 1.1 2.3 3.8 0.4 0.3 0.8 0.3 1.8 2.6 0.3 0.2 0.5 4.7 3.3 4.5 2.5 0.9 0.3 2.2 3.2 0.4 1.6 1.2 0.3 0.3 0.5 1.4 15.4 4.8 0.3 0.0 0.0 0.5 1.1 0.6 0.7 0.0 0.0 0.0 0.1 0.0 0.0 140.5 0.0 0.0 0.3 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.5 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 1.6 0.0 0.0 0.0 1.3 0.5 0.3 0.0 0.1 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.2 3.1 2.6 3.8 2.8 2.3 3.8 1.8 2.6 4.5 0.3 4.8 0.7 0.0 6.4 1.9 0.3 0.0 0.0 0.3 7.4 0.6 0.5 0.7 0.6 0.3 1.5 3.1 0.0 0.0 21.2 0.0 0.5 0.0 0.0 0.3 16.4 2.1 0.3 1.2 0.0 1.4 0.4 7.7 2.0 1.1 32.0 4.5 0.7 1.1 0.0 1.4 0.0 0.8 8.9 12.2 0.0 0.0 1.8 1.8 0.1 0.0 1.0 0.0 2.0 0.0 0.0 0.1 0.8 0.3 0.7 0.0 0.5 0.3 0.0 2.6 0.1 0.0 0.3 0.4 0.3 1.5 1.8 0.0 10.1 0.7 0.0 0.6 0.6 SLC9B2 "FLJ23984, NHA2, NHEDC2" ENSG00000164038 "Solute carrier family 9 member B2" Q86UD5 4 103019868-103085829 "Predicted membrane proteins, Transporters" "Antiport, Hydrogen ion transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 38.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 57.9;Exocrine glandular cells: 68.5;Inhibitory neurons: 57.2;Pancreatic endocrine cells: 94.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 11.8" "Group enriched" "Detected in many" 5 "B-cells: 5.1;NK-cells: 11.8;T-cells: 6.4" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047008 Uncertain Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Cell Junctions" "HPA047008: AB_2679901" "unprognostic (1.85e-1)" "unprognostic (5.43e-2)" "unprognostic (2.68e-1)" "unprognostic (1.11e-1)" "unprognostic (8.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.43e-2)" "unprognostic (3.78e-2)" "unprognostic (3.26e-1)" "unprognostic (2.53e-2)" "unprognostic (3.53e-2)" "unprognostic (1.67e-1)" "unprognostic (2.51e-5)" "unprognostic (2.23e-1)" "unprognostic (1.28e-1)" "unprognostic (1.90e-2)" "unprognostic (2.35e-5)" 7.8 6.0 11.2 5.2 11.7 4.6 5.7 10.9 12.8 6.2 3.2 6.2 1.1 6.8 2.3 3.4 5.6 7.6 6.2 12.5 11.1 2.5 38.7 3.6 5.9 11.4 9.1 6.7 2.4 0.3 8.5 3.9 12.7 4.1 2.7 12.8 2.4 5.0 3.0 3.0 3.7 7.7 7.0 3.6 4.9 3.6 10.0 3.6 2.9 3.5 5.6 6.5 4.9 11.2 4.9 2.1 5.2 10.5 26.0 20.7 0.0 22.0 7.8 3.2 3.0 2.5 3.0 29.3 3.7 24.3 5.1 1.4 12.2 9.3 4.8 24.7 7.5 30.2 7.5 21.8 13.5 22.5 8.8 18.7 10.8 7.7 27.3 11.1 15.3 8.3 10.1 22.1 10.7 1.7 15.3 10.8 4.4 0.1 6.4 0.0 6.0 12.2 9.0 2.4 17.5 14.9 10.0 2.3 6.0 1.4 2.6 13.4 17.6 7.5 4.3 11.6 6.9 16.8 14.2 21.7 8.7 17.5 3.0 0.0 0.1 0.0 4.9 0.0 6.4 5.1 5.1 4.1 0.9 3.0 3.1 3.8 0.0 11.8 0.1 1.6 2.4 1.8 11.2 11.7 10.9 12.8 12.5 11.1 11.4 9.1 12.7 7.0 10.0 11.2 13.9 0.0 0.5 15.0 15.6 4.8 3.4 2.0 6.2 9.7 3.1 2.8 2.5 8.6 1.1 0.0 27.1 0.5 6.5 0.2 0.0 14.1 12.1 1.1 8.6 17.8 3.0 17.2 57.9 68.5 2.3 13.2 22.4 0.9 1.3 10.3 6.1 39.5 1.4 8.4 57.2 1.1 4.1 1.3 5.3 6.9 5.6 3.4 10.6 5.6 3.9 0.7 0.0 32.6 17.6 94.7 0.3 5.3 12.0 4.9 0.0 1.4 1.1 2.3 6.6 16.5 11.5 5.8 4.2 5.6 3.8 0.3 7.9 4.8 0.3 1.3 SLCO2A1 "MATR1, OATP2A1, PGT, SLC21A2" ENSG00000174640 "Solute carrier organic anion transporter family member 2A1" Q92959 3 133932701-134052184 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 123.7" "Group enriched" "Detected in many" 4 "Distal enterocytes: 47.1;Endothelial cells: 65.2;Hepatic stellate cells: 146.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "EFO-21: 90.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA013742 Enhanced NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA013742: AB_2668877" "unprognostic (4.39e-3)" "unprognostic (2.84e-1)" "unprognostic (1.33e-1)" "prognostic favorable (9.69e-4)" "unprognostic (8.53e-2)" "unprognostic (2.32e-3)" "prognostic favorable (9.24e-5)" "unprognostic (1.92e-1)" "unprognostic (1.29e-1)" "unprognostic (7.60e-2)" "unprognostic (2.04e-2)" "unprognostic (6.87e-2)" "unprognostic (5.63e-3)" "prognostic unfavorable (3.25e-4)" "unprognostic (2.78e-1)" "unprognostic (1.45e-1)" "unprognostic (3.07e-2)" 30.4 42.5 1.6 16.8 1.6 0.0 18.1 1.3 2.7 30.9 9.1 24.7 10.2 46.3 6.1 18.8 28.3 18.8 26.4 1.5 1.6 52.8 2.4 123.7 9.2 2.0 1.6 5.2 20.8 28.7 15.8 23.4 2.2 36.5 18.0 0.0 20.8 84.7 2.1 13.5 29.3 33.5 1.9 24.2 23.6 1.3 2.3 8.4 89.3 3.4 9.6 21.3 20.3 1.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.5 4.3 0.5 0.0 0.1 0.1 0.0 90.6 0.9 0.0 11.2 0.1 0.0 0.1 0.1 0.1 0.0 5.8 0.0 2.4 0.0 0.0 3.4 0.2 0.0 0.2 0.0 1.5 0.0 0.0 0.0 0.0 0.5 0.0 0.7 0.6 6.0 0.0 0.0 0.0 0.0 8.7 0.0 0.1 0.0 4.6 1.5 0.0 3.7 0.1 0.0 22.1 0.0 4.5 0.1 0.4 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 1.6 1.3 2.7 1.5 1.6 2.0 1.6 2.2 1.9 2.3 1.7 19.8 0.0 2.5 0.0 2.1 5.1 9.1 0.5 8.6 0.0 0.8 3.9 4.6 1.5 1.6 3.7 0.0 1.5 0.0 47.1 0.0 2.8 1.0 0.9 0.2 65.2 1.2 0.0 8.1 3.3 4.0 8.7 18.8 1.6 1.3 0.1 146.7 0.6 0.2 0.0 1.7 4.1 0.0 2.2 0.4 0.8 0.3 0.7 0.0 2.8 0.0 0.0 0.0 0.0 0.1 14.0 15.8 0.0 0.0 1.5 3.2 2.1 0.8 0.0 0.0 0.4 1.1 0.4 0.2 2.0 1.7 0.8 1.1 0.1 0.6 2.2 SLIT2 "SLIL3, Slit-2" ENSG00000145147 "Slit guidance ligand 2" O94813 4 20251905-20620561 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Excitatory neurons: 256.7;Inhibitory neurons: 544.9;Oligodendrocytes: 157.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 98.0;BJ hTERT+: 200.8;BJ hTERT+ SV40 Large T+: 97.8;fHDF/TERT166: 117.8;HBF TERT88: 112.0;HEK 293: 88.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007590, HPA019511, HPA023088" Uncertain "Secreted in other tissues" NA NA 77000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB007590: , HPA019511: AB_1857226, HPA023088: AB_1857227" "unprognostic (1.44e-1)" "unprognostic (4.54e-2)" "unprognostic (3.26e-2)" "unprognostic (6.13e-2)" "unprognostic (9.01e-3)" "unprognostic (6.49e-2)" "unprognostic (1.71e-1)" "unprognostic (4.78e-2)" "unprognostic (1.73e-1)" "unprognostic (6.16e-3)" "unprognostic (5.32e-2)" "unprognostic (4.30e-2)" "prognostic favorable (6.51e-4)" "unprognostic (4.93e-3)" "unprognostic (6.80e-3)" "unprognostic (1.74e-1)" "unprognostic (7.16e-4)" 8.0 24.9 3.2 3.3 6.4 0.0 9.4 0.0 14.0 24.0 11.7 11.5 2.4 16.4 9.9 5.8 13.1 9.4 7.8 6.6 20.5 12.3 2.0 34.9 1.8 7.9 3.1 4.3 2.8 1.5 8.8 25.2 4.5 12.6 5.4 13.2 6.1 15.7 2.9 3.8 4.8 24.9 0.4 14.2 9.0 1.3 17.6 2.4 9.2 5.1 1.2 13.1 13.9 2.4 0.1 0.0 54.6 0.0 37.8 34.8 1.7 98.0 200.8 97.8 36.9 0.4 0.1 0.0 3.4 117.8 0.2 1.2 15.7 7.9 112.0 0.2 88.3 0.0 0.4 0.0 7.2 0.9 0.0 8.5 0.0 63.6 18.6 2.1 35.0 0.0 0.0 0.0 4.6 0.0 0.0 0.4 1.7 0.0 6.3 61.2 0.5 0.0 1.0 0.1 3.5 0.8 0.0 0.2 0.4 1.9 0.2 0.2 2.0 34.9 5.0 35.0 54.2 0.0 0.1 0.0 0.9 0.0 19.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 6.4 0.0 14.0 6.6 20.5 7.9 3.1 4.5 0.4 17.6 2.4 1.6 0.0 9.0 10.1 0.0 8.0 2.0 0.1 0.6 47.6 1.0 0.6 5.2 1.5 1.3 0.0 0.0 1.1 0.0 0.6 1.9 1.7 0.6 6.4 1.9 2.0 1.2 0.0 256.7 0.5 1.2 58.8 0.0 7.1 2.5 1.3 4.2 0.2 1.9 0.0 544.9 0.0 0.0 1.0 9.7 1.7 26.4 0.7 8.8 31.9 0.0 1.3 0.0 43.7 157.9 0.2 0.0 26.7 0.1 3.7 0.0 11.5 7.4 2.1 6.6 3.2 6.4 0.2 1.7 1.2 6.7 2.1 1.1 20.3 0.1 1.9 SLIT3 "MEGF5, SLIL2, Slit-3, SLIT1, slit2" ENSG00000184347 "Slit guidance ligand 3" O75094 5 168661733-169301139 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 202.3;Fibroblasts: 112.7;Sertoli cells: 85.5;Smooth muscle cells: 99.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 12.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Cell line enhanced" "Detected in many" "ASC diff: 310.3;fHDF/TERT166: 116.0;RT4: 101.1;SH-SY5Y: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051630 Approved Supported "Cell Junctions" "Secreted in other tissues" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Cell Junctions" "HPA051630: AB_2681557" "unprognostic (2.86e-2)" "unprognostic (2.64e-1)" "unprognostic (4.43e-2)" "unprognostic (2.92e-2)" "unprognostic (2.50e-2)" "unprognostic (3.53e-2)" "unprognostic (9.21e-3)" "unprognostic (3.06e-2)" "unprognostic (1.71e-1)" "unprognostic (9.50e-3)" "unprognostic (1.57e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.45e-5)" "unprognostic (5.90e-3)" "unprognostic (8.56e-2)" "unprognostic (4.27e-1)" "unprognostic (3.53e-1)" 61.9 20.7 10.0 11.9 10.6 0.1 32.7 11.9 7.5 36.4 0.3 20.0 5.4 23.9 8.8 21.4 22.2 43.5 39.7 12.3 4.3 16.7 1.5 38.1 6.2 12.9 0.7 17.0 7.8 44.9 4.4 21.7 11.6 10.3 9.7 3.1 16.8 15.4 4.4 25.8 10.4 27.1 0.3 14.3 10.1 2.7 6.9 20.0 23.3 6.5 4.2 55.5 24.3 2.2 0.0 11.0 0.1 0.0 310.3 5.7 0.0 18.1 3.1 4.0 8.4 0.1 0.0 0.0 4.2 116.0 13.1 0.0 2.9 1.2 0.3 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 1.8 4.2 0.5 3.9 44.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 101.1 1.1 73.3 0.0 0.0 0.0 12.5 0.0 0.0 0.0 3.0 1.9 25.5 0.1 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 10.0 10.6 11.9 7.5 12.3 4.3 12.9 0.7 11.6 0.3 6.9 2.2 11.7 0.0 2.3 4.2 0.5 26.6 1.8 5.5 3.4 8.6 1.1 3.8 25.9 0.0 0.4 0.0 0.0 2.3 0.5 0.0 0.0 0.2 11.9 1.3 35.7 5.4 0.0 0.0 202.3 0.0 0.5 112.7 4.6 3.6 1.3 0.5 1.8 0.0 1.2 0.0 20.2 0.0 0.0 0.0 32.5 8.2 0.9 1.1 35.6 14.0 0.0 13.7 0.0 8.0 2.9 0.0 0.0 0.4 0.8 1.1 0.1 1.9 0.2 0.9 85.5 1.8 99.3 1.2 2.2 1.1 17.6 1.1 1.8 0.3 0.0 0.8 SMAD1 "JV4-1, MADH1, MADR1" ENSG00000170365 "SMAD family member 1" Q15797 4 145481194-145559176 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 195.9;Endothelial cells: 76.3;Late spermatids: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 46.2;non-classical monocyte: 22.2" "Group enriched" "Detected in many" 5 "granulocytes: 46.2;monocytes: 22.2" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 110.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005389 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "CAB005389: AB_656608" "unprognostic (8.20e-2)" "unprognostic (1.63e-1)" "unprognostic (2.76e-2)" "unprognostic (1.11e-1)" "unprognostic (3.74e-1)" "unprognostic (6.85e-2)" "unprognostic (1.70e-1)" "unprognostic (6.02e-2)" "unprognostic (2.30e-1)" "unprognostic (8.24e-2)" "unprognostic (5.31e-2)" "unprognostic (4.68e-2)" "unprognostic (1.73e-3)" "unprognostic (1.48e-1)" "unprognostic (5.88e-2)" "unprognostic (1.14e-3)" "unprognostic (3.15e-2)" 19.6 5.3 16.7 10.9 21.9 5.8 15.9 15.3 18.2 20.4 6.9 20.4 15.4 29.0 32.7 16.3 24.4 17.1 13.1 13.2 16.6 12.6 20.2 12.3 17.6 14.6 18.3 11.7 13.3 29.1 6.0 11.4 14.5 12.5 20.8 6.5 12.9 17.2 20.7 24.4 15.7 30.4 13.6 14.0 10.6 13.9 16.4 18.3 17.4 17.8 13.7 17.9 8.9 13.6 9.6 12.6 23.5 27.3 8.7 12.8 11.5 13.9 32.6 22.0 16.4 6.2 34.0 9.8 8.0 31.8 9.7 14.1 26.6 30.2 12.8 0.0 13.5 0.0 10.0 13.1 23.2 15.8 2.4 17.6 35.2 11.8 22.9 17.9 110.7 20.7 11.1 0.4 27.0 9.6 24.4 0.3 21.8 15.3 14.6 47.0 21.1 28.5 25.9 17.1 35.3 17.6 18.8 40.3 9.6 14.1 14.0 0.2 32.4 10.5 14.5 11.3 8.6 31.1 0.0 56.1 16.7 0.3 11.1 46.2 3.6 1.5 0.0 9.4 0.0 0.0 0.6 0.0 6.8 0.1 0.3 0.0 0.0 2.4 22.2 0.0 1.3 1.3 16.7 21.9 15.3 18.2 13.2 16.6 14.6 18.3 14.5 13.6 16.4 13.6 62.9 9.6 10.9 54.9 0.1 11.5 17.5 22.0 45.5 6.6 8.6 9.3 3.6 12.8 16.3 14.7 14.6 5.2 0.8 13.2 7.9 12.6 195.9 19.5 12.1 76.3 9.1 8.4 47.7 18.5 2.7 11.5 12.2 24.8 0.0 10.0 10.4 12.0 2.5 10.1 43.2 10.4 28.5 6.5 2.7 80.7 4.4 4.5 1.8 26.2 3.2 5.3 0.0 66.9 22.0 12.0 10.2 5.7 0.3 17.5 6.6 11.5 12.7 5.9 0.0 19.0 10.6 8.3 16.8 19.9 12.6 2.2 1.2 6.9 8.8 17.2 SMAD6 "HsT17432, MADH6, MADH7" ENSG00000137834 "SMAD family member 6" O43541 15 66702236-66782849 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 30.1;lung: 27.9" "Cell type enhanced" "Detected in many" "Endothelial cells: 25.1;Hepatic stellate cells: 91.4;Microglial cells: 57.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 29.8;HaCaT: 18.2;HeLa: 28.6;U-2197: 17.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA061917 Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Nuclear bodies, Golgi apparatus" "HPA061917: AB_2684637" "unprognostic (1.20e-1)" "unprognostic (7.43e-3)" "unprognostic (5.62e-2)" "unprognostic (1.26e-1)" "unprognostic (3.02e-1)" "unprognostic (3.50e-3)" "unprognostic (9.59e-2)" "unprognostic (4.50e-1)" "unprognostic (3.47e-2)" "unprognostic (1.50e-1)" "unprognostic (1.10e-3)" "unprognostic (1.68e-1)" "unprognostic (1.67e-2)" "unprognostic (1.55e-3)" "unprognostic (4.30e-2)" "unprognostic (1.33e-1)" "prognostic favorable (5.45e-5)" 9.5 2.6 5.2 1.6 4.9 0.1 7.6 4.9 4.3 6.8 8.6 3.7 1.9 6.2 0.6 2.1 5.4 1.4 30.1 3.4 4.1 8.9 6.7 27.9 0.5 7.6 5.4 5.9 2.7 1.1 3.4 7.4 5.8 7.0 1.1 0.9 2.1 3.5 1.6 2.4 3.9 0.9 4.4 2.6 5.5 1.8 6.8 0.4 15.5 1.5 0.2 8.0 5.7 4.6 1.3 10.2 1.6 3.5 6.0 1.6 9.4 7.2 0.1 1.1 0.1 2.0 4.6 0.7 29.8 6.1 0.9 18.2 2.2 0.0 0.2 2.3 8.4 16.1 28.6 1.7 0.7 0.1 1.2 2.0 0.0 0.1 0.0 3.4 1.3 5.1 1.4 1.0 0.5 2.0 0.1 4.4 3.0 10.5 3.8 0.0 1.8 2.2 3.4 8.1 3.6 1.6 3.9 4.3 0.8 5.9 1.4 2.9 6.2 4.3 5.5 17.6 1.4 0.5 1.8 0.3 3.1 5.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 4.9 4.9 4.3 3.4 4.1 7.6 5.4 5.8 4.4 6.8 4.6 19.8 12.8 6.0 5.2 0.9 0.8 1.2 2.1 0.6 0.6 0.9 1.1 4.9 4.3 3.0 1.8 2.1 0.8 0.1 4.3 3.9 4.7 3.4 8.3 5.5 25.1 0.0 0.0 0.3 5.8 0.9 4.9 5.1 6.5 4.5 5.9 91.4 4.0 1.7 0.0 0.3 2.1 0.0 10.0 0.3 1.4 2.8 1.2 0.0 57.1 0.7 10.2 0.0 0.5 0.4 8.4 1.5 8.2 0.0 1.3 2.1 1.9 0.1 0.6 0.0 0.9 1.5 0.2 3.2 0.4 0.1 0.8 0.4 0.1 5.5 0.4 SMCO3 "C12orf69, LOC440087" ENSG00000179256 "Single-pass membrane protein with coiled-coil domains 3" A2RU48 12 14804650-14814182 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 3.4;kidney: 3.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 2.8;Collecting duct cells: 1.8;Distal tubular cells: 5.9;Erythroid cells: 2.7;Hepatic stellate cells: 4.6;Proximal tubular cells: 7.3" "Cancer enhanced" "Detected in some" "prostate cancer: 3.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "AN3-CA: 1.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in single" 7 "spinal cord: 3.6" "HPA040574, HPA047804" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cytosol" "HPA040574: AB_2677026, HPA047804: AB_2680160" "unprognostic (1.16e-1)" "unprognostic (2.09e-4)" "unprognostic (2.40e-4)" "unprognostic (5.10e-2)" "unprognostic (3.88e-2)" "unprognostic (6.45e-2)" "unprognostic (4.43e-2)" "unprognostic (2.86e-2)" "unprognostic (1.52e-1)" "unprognostic (1.32e-1)" "unprognostic (7.31e-2)" "unprognostic (3.66e-2)" "unprognostic (1.48e-8)" "unprognostic (2.85e-1)" "unprognostic (7.53e-3)" "unprognostic (2.05e-1)" "unprognostic (1.38e-1)" 0.5 0.4 0.0 0.1 0.2 0.3 0.2 0.1 0.1 3.4 0.3 0.2 0.0 0.3 0.1 0.0 0.3 1.8 0.9 0.1 0.2 3.0 1.5 1.1 0.5 0.1 0.2 0.2 0.2 0.5 0.2 1.1 0.1 0.8 0.1 1.3 0.1 1.6 0.1 0.1 0.1 0.1 0.1 1.8 0.1 0.2 0.1 0.0 0.8 0.0 0.1 0.1 0.6 0.3 0.0 0.0 0.1 1.9 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.4 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.5 2.8 0.0 1.8 0.0 0.1 0.0 0.0 5.9 0.2 0.0 0.0 0.2 0.3 0.0 2.7 0.1 0.2 0.3 0.2 0.0 0.0 0.0 0.0 4.6 0.2 0.1 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 7.3 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 SMDT1 "C22orf32, DDDD, dJ186O1.1, EMRE" ENSG00000183172 "Single-pass membrane protein with aspartate rich tail 1" Q9H4I9 22 42079691-42084284 "Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032117, HPA060340" Uncertain Supported Nucleoplasm,Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA032117: AB_10601093, HPA060340: AB_2684257" "unprognostic (1.11e-2)" "unprognostic (1.46e-3)" "unprognostic (5.77e-2)" "prognostic favorable (5.32e-8)" "unprognostic (1.25e-1)" "unprognostic (2.40e-1)" "unprognostic (1.03e-1)" "unprognostic (2.07e-2)" "unprognostic (2.55e-1)" "unprognostic (4.84e-2)" "prognostic favorable (5.87e-4)" "unprognostic (2.96e-1)" "prognostic favorable (2.36e-9)" "unprognostic (1.91e-1)" "unprognostic (2.65e-1)" "unprognostic (1.45e-1)" "unprognostic (9.72e-3)" 12.2 13.9 21.6 6.1 22.2 17.6 19.5 25.7 27.7 14.6 21.2 14.7 10.3 12.3 19.5 12.6 15.2 7.4 20.0 22.1 22.0 18.2 15.1 9.7 16.1 21.6 21.4 22.5 21.5 18.0 14.9 7.3 22.2 16.1 11.2 16.0 22.7 13.4 35.6 14.8 13.5 8.4 21.3 12.6 17.7 6.9 21.3 12.4 18.6 37.9 12.2 12.4 11.9 22.4 5.7 3.7 7.4 8.9 13.1 9.5 5.8 2.0 10.0 12.1 10.5 7.1 5.3 7.8 2.4 10.3 3.4 6.1 9.8 10.4 7.7 3.8 15.7 4.7 8.1 10.3 16.5 8.6 5.9 7.4 17.3 4.8 9.9 6.9 12.2 5.1 7.9 12.3 8.4 11.2 12.1 13.0 2.8 14.1 2.7 10.8 6.5 20.8 15.5 6.4 9.2 6.0 5.0 11.1 12.8 3.7 9.3 9.3 4.8 5.1 5.3 4.5 3.9 8.2 9.8 16.9 7.9 8.5 4.1 4.0 5.8 2.9 3.1 3.1 5.9 5.9 8.6 4.5 8.4 7.2 9.3 6.0 0.5 5.5 4.5 6.4 5.4 5.4 21.6 22.2 25.7 27.7 22.1 22.0 21.6 21.4 22.2 21.3 21.3 22.4 161.1 83.3 109.3 11.8 295.0 166.7 202.2 157.3 191.2 71.6 400.9 477.3 350.9 237.4 160.3 204.1 20.9 308.7 127.8 285.6 573.2 160.0 114.0 156.8 81.1 138.2 345.2 135.7 10.5 199.6 190.6 127.8 150.3 127.2 91.4 55.4 161.3 380.1 256.1 55.5 12.8 356.5 262.4 164.5 200.6 131.9 189.2 187.7 211.7 5.6 125.8 196.4 124.6 7.5 13.8 193.7 314.0 149.0 275.8 238.2 486.7 623.4 223.7 109.5 124.9 133.6 202.7 256.0 55.5 271.5 274.1 308.8 186.3 151.7 308.8 272.2 SMIM1 Vel ENSG00000235169 "Small integral membrane protein 1 (Vel blood group)" B2RUZ4 1 3772749-3775982 "Blood group antigen proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 40.3;testis: 42.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 84.1;Erythroid cells: 404.4;Granulosa cells: 81.5;Proximal tubular cells: 247.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "eosinophil: 48.5" "Lineage enriched" "Detected in many" 12 "granulocytes: 48.5" "Group enriched" "Detected in many" 4 "HEL: 68.0;Hep G2: 32.5;K-562: 33.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA069088 Enhanced NA NA 340000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "HPA069088: AB_2686080" "unprognostic (9.50e-3)" "unprognostic (7.19e-4)" "unprognostic (5.40e-2)" "unprognostic (2.10e-2)" "unprognostic (2.50e-3)" "unprognostic (3.25e-1)" "unprognostic (2.63e-3)" "unprognostic (2.13e-2)" "unprognostic (2.31e-2)" "unprognostic (9.85e-2)" "unprognostic (2.90e-1)" "unprognostic (1.87e-1)" "unprognostic (2.25e-2)" "unprognostic (7.10e-2)" "unprognostic (2.91e-2)" "unprognostic (5.56e-2)" "unprognostic (1.32e-2)" 2.6 2.7 1.8 0.4 2.6 32.1 3.2 3.8 3.0 5.8 6.2 2.9 0.7 2.8 1.1 1.4 3.4 1.3 40.3 1.4 3.9 16.9 13.1 3.7 1.0 8.7 5.3 8.7 9.4 4.3 16.0 2.1 9.0 6.9 0.1 0.4 17.3 5.5 1.1 2.1 2.1 0.2 5.5 4.0 6.6 42.2 3.6 0.4 9.3 0.2 0.5 3.4 3.6 6.2 0.3 1.4 1.4 3.0 0.0 0.0 5.0 0.9 1.2 0.0 0.0 3.5 3.9 0.1 6.3 0.0 0.2 1.3 0.4 1.5 0.0 6.1 3.6 68.0 0.0 32.5 2.4 0.0 1.2 2.1 0.8 0.3 0.5 2.9 0.0 0.3 33.9 1.2 0.0 7.8 0.0 2.1 0.3 3.4 6.0 0.0 0.0 9.9 3.8 1.0 1.6 6.3 0.2 6.8 4.8 0.5 7.0 3.7 0.4 0.0 0.8 0.0 0.0 2.8 0.8 0.2 0.0 0.0 0.2 4.4 2.0 48.5 1.1 1.0 0.4 2.5 1.6 0.6 0.6 3.7 4.0 1.9 3.2 0.2 0.4 0.6 1.2 2.2 1.8 2.6 3.8 3.0 1.4 3.9 8.7 5.3 9.0 5.5 3.6 6.2 1.1 6.4 20.1 0.7 5.9 1.7 13.1 4.4 10.2 0.4 31.1 35.9 57.0 8.6 8.1 16.5 0.0 23.4 1.4 1.6 84.1 17.2 10.8 3.7 1.2 3.9 5.4 404.4 0.1 14.5 18.8 10.1 6.6 3.5 1.3 81.5 3.9 50.2 10.4 1.7 0.1 3.9 8.2 8.9 1.0 27.8 9.9 8.5 42.7 0.0 4.3 47.0 2.1 0.0 1.6 13.7 1.7 9.8 11.1 10.2 1.9 247.9 2.2 1.5 0.0 3.6 4.3 8.7 20.4 1.7 1.1 6.7 4.6 3.0 4.3 9.1 SMPDL3A "ASM3A, ASML3a, FLJ20177, yR36GH4.1" ENSG00000172594 "Sphingomyelin phosphodiesterase acid like 3A" Q92484 6 122789049-122809720 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 156.3;Distal enterocytes: 291.5;Paneth cells: 157.5;Proximal enterocytes: 383.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "basophil: 80.9" "Lineage enriched" "Detected in many" 11 "granulocytes: 80.9" "Cell line enhanced" "Detected in many" "ASC diff: 44.2;hTCEpi: 36.9;OE19: 58.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030148 Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria "Secreted to blood" No No 26000000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Nucleoli, Mitochondria" "HPA030148: AB_10601591" "unprognostic (2.60e-1)" "unprognostic (1.22e-1)" "prognostic favorable (6.11e-4)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (8.30e-3)" "unprognostic (3.37e-1)" "unprognostic (1.46e-1)" "unprognostic (1.83e-1)" "unprognostic (1.53e-1)" "unprognostic (1.39e-1)" "unprognostic (7.72e-2)" "unprognostic (2.27e-2)" "unprognostic (3.44e-2)" "unprognostic (8.46e-2)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" 15.0 23.3 4.6 18.7 5.1 22.9 23.7 8.2 9.4 72.8 8.9 60.7 45.5 13.3 6.5 13.6 7.9 17.2 5.6 5.3 5.7 47.4 80.0 14.1 21.4 5.9 5.4 9.1 20.8 32.4 7.5 44.0 5.9 21.8 65.7 6.0 13.7 16.6 39.8 64.5 77.3 8.5 5.7 27.0 30.5 2.9 5.4 5.1 9.1 55.8 16.2 35.5 30.9 7.7 0.3 2.6 6.1 2.8 44.2 19.9 19.5 10.4 27.8 3.1 6.6 3.3 2.7 0.0 1.4 6.6 8.2 4.9 1.7 5.3 2.6 0.0 5.4 2.5 9.8 9.0 28.3 0.0 0.1 24.4 36.9 3.0 5.3 12.0 5.5 0.0 3.8 0.0 12.7 9.3 0.0 0.2 1.1 58.8 8.0 0.0 10.8 0.4 15.1 4.2 4.4 0.1 1.5 18.5 27.9 3.9 3.1 1.4 11.0 5.9 3.5 0.6 6.8 0.0 0.0 0.0 8.7 4.9 13.7 80.9 4.0 1.1 0.0 4.3 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 1.3 0.0 7.5 0.0 0.0 1.4 4.6 5.1 8.2 9.4 5.3 5.7 5.9 5.4 5.9 5.7 5.4 7.7 11.8 3.2 17.8 5.2 2.4 53.7 24.5 13.7 15.9 3.0 12.2 6.6 4.0 25.8 9.7 5.5 4.2 156.3 0.4 291.5 56.7 24.6 0.2 4.2 12.6 7.1 48.7 5.7 7.4 25.7 40.4 46.3 34.7 5.2 10.1 0.8 18.9 77.8 62.7 3.3 10.5 61.7 59.0 126.3 10.0 1.2 15.5 33.4 35.6 11.2 9.9 11.5 2.1 11.1 11.0 19.5 157.5 14.3 0.9 16.7 383.1 129.3 7.5 6.2 13.1 12.8 9.9 1.1 3.7 15.5 76.0 115.1 2.0 11.4 38.9 16.6 SMYD4 "KIAA1936, ZMYND21" ENSG00000186532 "SET and MYND domain containing 4" Q8IYR2 17 1779485-1830634 "Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030059 Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "Nucleoplasm, Cytosol" "HPA030059: AB_2191728" "unprognostic (1.45e-1)" "unprognostic (2.48e-1)" "unprognostic (2.47e-1)" "unprognostic (4.23e-2)" "unprognostic (1.13e-2)" "unprognostic (3.66e-2)" "unprognostic (4.03e-2)" "unprognostic (1.04e-1)" "unprognostic (1.79e-2)" "unprognostic (4.95e-2)" "unprognostic (1.83e-3)" "unprognostic (9.26e-3)" "unprognostic (3.63e-2)" "unprognostic (1.33e-2)" "unprognostic (7.35e-2)" "unprognostic (1.52e-1)" "unprognostic (1.18e-1)" 7.4 6.6 4.1 6.0 3.6 3.4 7.3 8.0 4.5 7.9 3.7 7.5 7.0 6.5 5.0 3.9 7.3 3.6 7.0 3.5 3.5 3.7 4.9 5.6 6.8 3.7 3.2 9.5 6.7 3.6 6.6 4.7 4.0 6.5 4.8 7.6 7.3 5.6 13.7 6.6 7.4 5.9 2.2 6.3 4.9 5.8 4.3 6.2 5.7 10.2 6.5 7.2 6.2 5.6 7.4 13.7 13.5 9.6 9.0 6.1 15.7 11.9 6.7 12.3 12.5 22.0 6.2 19.7 7.8 4.8 8.3 14.2 12.9 7.7 15.3 5.7 13.1 7.2 15.9 6.0 4.5 7.4 6.8 4.4 6.8 12.7 11.1 6.3 6.2 16.6 7.6 7.5 9.7 4.6 13.6 5.3 6.2 8.7 6.6 16.7 6.9 5.0 4.9 8.8 5.5 7.6 11.0 4.5 11.1 10.9 6.7 4.5 5.9 12.0 6.1 10.0 10.4 5.2 7.5 7.1 6.8 6.4 11.9 12.0 2.4 2.3 5.1 3.0 4.3 4.0 3.0 3.3 1.5 2.7 3.4 5.0 1.3 3.1 2.4 4.5 3.5 2.1 4.1 3.6 8.0 4.5 3.5 3.5 3.7 3.2 4.0 2.2 4.3 5.6 22.9 6.4 27.8 6.5 12.9 5.0 9.3 11.9 14.8 19.3 6.9 8.4 6.3 14.3 14.0 7.3 33.3 9.7 16.5 6.9 1.9 5.7 20.2 3.7 8.9 10.9 3.6 9.7 11.7 3.3 10.9 14.2 4.1 3.5 7.6 14.7 17.2 6.7 12.9 26.9 12.1 5.2 12.2 23.3 9.2 5.9 27.1 17.4 5.4 13.1 16.4 7.9 43.3 4.5 7.1 4.2 2.0 24.8 10.1 7.2 23.3 2.9 17.8 19.9 46.0 43.6 23.9 12.6 14.8 5.1 6.7 8.1 12.1 6.1 6.4 3.5 SNCG "BCSG1, persyn, SR" ENSG00000173267 "Synuclein gamma" O76070 10 86958599-86963258 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 268.3;brain: 411.2" "Cell type enhanced" "Detected in many" "Adipocytes: 164.9;Breast myoepithelial cells: 156.1;Endothelial cells: 143.3;Hepatic stellate cells: 206.0;Smooth muscle cells: 234.3;Urothelial cells: 358.3" "Group enriched" "Detected in all" 8 "ovarian cancer: 84.1;urothelial cancer: 301.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 748.2;RT4: 483.5;T-47d: 151.7;TIME: 160.9" "Region enhanced" "Detected in all" "pons and medulla: 279.9" "Low region specificity" "Detected in many" "CAB001452, HPA014404, CAB040581, CAB080022" Enhanced Supported NA NA 23000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "CAB001452: AB_564020, CAB040581: , CAB080022: , HPA014404: AB_1857715" "unprognostic (2.06e-1)" "unprognostic (2.58e-1)" "unprognostic (6.87e-3)" "unprognostic (1.45e-2)" "unprognostic (1.10e-1)" "unprognostic (1.91e-1)" "unprognostic (4.76e-3)" "unprognostic (8.99e-2)" "unprognostic (1.27e-1)" "unprognostic (1.44e-1)" "unprognostic (3.85e-3)" "unprognostic (3.75e-1)" "prognostic unfavorable (2.29e-8)" "prognostic unfavorable (7.15e-4)" "unprognostic (2.35e-1)" "unprognostic (2.36e-2)" "unprognostic (3.77e-3)" 208.2 268.3 215.6 11.9 150.8 0.0 98.1 199.9 313.3 33.3 44.0 27.0 9.2 22.9 15.1 25.4 64.5 12.7 31.7 190.2 387.7 22.3 4.3 13.9 11.6 411.2 276.4 42.1 5.3 3.3 11.1 11.9 357.8 36.6 4.9 52.7 22.9 101.6 14.6 28.6 18.8 10.1 155.3 64.2 16.4 5.4 304.7 9.0 20.3 13.7 25.6 204.8 38.9 148.8 2.6 6.8 0.7 1.1 0.3 3.9 0.7 0.8 0.0 0.0 0.0 1.1 748.2 0.0 22.6 1.4 0.0 71.0 0.0 3.4 0.0 0.1 1.4 3.6 109.6 2.0 1.4 0.0 1.8 2.8 55.5 0.0 0.6 0.2 49.8 0.0 5.3 0.0 0.0 0.6 0.2 0.4 11.3 0.0 0.4 0.0 0.4 0.3 0.2 483.5 0.1 0.0 6.5 8.7 0.9 1.0 151.7 0.3 160.9 1.1 3.7 0.3 0.0 0.2 0.0 0.0 0.8 3.6 0.5 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.1 215.6 150.8 199.9 313.3 190.2 387.7 411.2 276.4 357.8 155.3 304.7 148.8 164.9 0.0 0.0 7.5 1.5 28.8 65.9 16.3 11.4 32.2 61.1 156.1 1.9 8.6 14.6 55.2 6.2 19.4 2.8 0.1 125.2 3.6 0.6 0.4 0.8 143.3 0.0 2.7 9.9 1.1 0.6 14.2 0.5 0.6 0.0 0.1 206.0 0.8 5.5 87.5 28.0 0.0 20.3 1.8 27.3 3.7 59.0 2.2 23.2 6.5 0.9 66.4 0.0 4.5 7.5 4.7 2.2 9.8 0.0 14.2 0.3 1.3 2.4 109.3 92.1 2.5 234.3 0.6 0.7 2.6 19.7 6.2 2.7 16.9 0.0 358.3 SNORC "ASCL830, C2orf82, UNQ830" ENSG00000182600 "Secondary ossification center associated regulator of chondrocyte maturation" Q6UX34 2 232857270-232878708 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 55.0;breast: 14.2;skin 1: 32.2" "Group enriched" "Detected in some" 22 "Breast glandular cells: 367.0;Breast myoepithelial cells: 324.9" "Cancer enhanced" "Detected in many" "liver cancer: 7.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 20 "basophil: 2.8" "Lineage enriched" "Detected in single" 20 "granulocytes: 2.8" "Cell line enriched" "Detected in some" 13 "Hep G2: 59.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052824 Approved Approved Nucleoplasm,Nucleoli "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 35: Glandular cells - Unknown function" "Nucleoplasm, Nucleoli" "HPA052824: AB_2681964" "unprognostic (4.58e-3)" "unprognostic (1.31e-1)" "unprognostic (2.47e-2)" "prognostic unfavorable (3.56e-4)" "unprognostic (1.27e-1)" "unprognostic (2.11e-1)" "unprognostic (3.06e-1)" "unprognostic (4.71e-1)" "unprognostic (1.23e-3)" "unprognostic (3.52e-1)" "unprognostic (1.79e-1)" "unprognostic (2.00e-1)" "unprognostic (4.30e-7)" "unprognostic (1.83e-3)" "unprognostic (8.15e-2)" "unprognostic (1.58e-2)" "unprognostic (1.33e-2)" 1.3 0.9 6.7 0.2 14.1 0.5 14.2 21.2 8.5 0.7 0.2 3.3 0.9 0.7 0.5 1.0 1.2 0.0 0.8 11.9 23.5 1.3 7.4 0.8 0.6 37.8 14.8 0.7 1.7 0.3 1.6 0.2 28.3 1.5 0.3 0.6 4.7 0.1 1.0 32.2 1.7 0.1 38.2 1.1 0.8 8.1 14.2 0.1 0.6 0.0 0.0 0.9 0.8 55.0 0.9 0.0 0.3 1.4 1.0 1.6 2.4 0.3 0.0 0.3 0.7 0.0 0.2 0.0 0.7 0.1 0.5 0.5 0.0 0.0 0.0 0.6 2.1 0.5 0.4 59.6 0.8 0.1 1.7 0.0 1.3 0.4 0.8 0.7 1.6 0.6 0.1 0.2 0.2 0.2 0.2 0.5 0.0 0.0 2.2 0.4 0.6 0.4 0.1 0.9 0.2 0.8 0.4 0.0 2.2 1.0 0.1 2.6 0.9 0.2 0.8 0.8 0.8 3.8 4.7 0.2 0.1 1.4 0.4 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 14.1 21.2 8.5 11.9 23.5 37.8 14.8 28.3 38.2 14.2 55.0 3.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 367.0 324.9 0.0 0.0 0.0 1.8 0.0 0.1 10.1 0.0 5.9 0.5 0.0 3.8 0.4 6.3 0.0 0.0 0.0 0.8 0.1 2.9 0.0 2.3 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.0 2.3 0.9 0.0 0.0 SNTB1 "59-DAP, A1B, BSYN2, SNT2, SNT2B1, TIP-43" ENSG00000172164 "Syntrophin beta 1" Q13884 8 120535745-120813273 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 89.3" "Cell type enhanced" "Detected in many" "Astrocytes: 70.2;Hepatocytes: 66.8;Microglial cells: 45.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 84.9;OE19: 78.5;U-266/70: 77.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA024659 Uncertain "Intracellular and membrane" NA NA 25000 "Cluster 2: Granulocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA024659: AB_1857713" "unprognostic (1.32e-1)" "unprognostic (2.77e-2)" "unprognostic (6.12e-2)" "unprognostic (1.42e-1)" "unprognostic (6.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.76e-2)" "unprognostic (6.41e-3)" "unprognostic (2.07e-1)" "unprognostic (3.88e-1)" "unprognostic (1.31e-1)" "unprognostic (4.72e-1)" "unprognostic (2.00e-2)" "unprognostic (5.08e-2)" "unprognostic (5.88e-2)" "unprognostic (1.03e-1)" "unprognostic (1.71e-1)" 7.9 66.4 7.5 5.5 6.5 18.9 8.0 5.8 5.9 5.6 42.9 6.2 5.7 4.4 2.7 8.4 6.0 4.3 4.9 6.1 11.8 12.6 89.3 15.4 7.3 7.2 11.4 2.5 45.0 1.4 2.6 8.6 7.8 4.8 6.4 4.8 34.8 3.4 28.2 9.8 6.3 3.1 6.0 11.9 24.1 9.8 9.1 3.4 61.4 32.4 3.5 3.9 3.6 6.5 0.1 1.8 0.7 0.0 11.3 22.9 0.1 6.0 36.7 1.8 2.7 12.0 1.6 0.0 10.7 6.8 0.0 0.1 2.0 0.0 1.3 5.6 6.5 0.0 0.3 84.9 1.2 16.9 0.0 11.4 0.0 10.1 0.0 14.9 0.4 10.4 0.0 32.3 5.9 3.3 0.0 13.7 2.1 78.5 8.7 0.0 43.8 0.1 34.4 2.0 0.1 0.4 2.4 12.5 30.2 0.7 1.5 30.5 0.0 23.7 1.4 0.0 2.0 77.2 33.0 34.8 18.4 49.0 26.7 1.8 0.8 2.7 2.2 0.4 0.5 0.5 0.4 1.1 0.6 0.2 1.1 1.1 0.1 1.6 0.3 0.0 0.0 0.6 7.5 6.5 5.8 5.9 6.1 11.8 7.2 11.4 7.8 6.0 9.1 6.5 1.9 12.8 27.2 70.2 4.7 0.4 0.7 0.9 1.8 2.4 8.5 6.0 2.0 2.8 9.0 5.5 2.1 0.8 8.4 1.3 9.8 1.5 9.3 2.4 5.8 4.2 0.0 14.1 2.4 10.9 2.2 9.8 11.2 6.2 1.3 8.8 13.2 66.8 11.3 0.0 3.1 3.9 16.2 29.9 4.3 4.2 4.7 18.1 1.8 45.9 12.1 16.0 18.6 2.5 12.2 4.3 1.9 13.2 2.8 1.1 0.1 3.3 13.8 0.7 13.1 3.9 14.3 1.1 0.2 10.1 1.0 0.3 12.0 11.0 4.1 0.6 SNTB2 "D16S2531E, EST25263, SNT2B2, SNT3, SNTL" ENSG00000168807 "Syntrophin beta 2" Q13425 16 69187129-69309052 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 151.4;Muller glia cells: 214.1;Rod photoreceptor cells: 136.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SiHa: 42.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001394 Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus, Plasma membrane" Nucleoplasm "HPA001394: AB_1080170" "unprognostic (4.86e-1)" "unprognostic (3.26e-2)" "unprognostic (2.77e-2)" "unprognostic (8.07e-3)" "unprognostic (6.46e-2)" "unprognostic (9.68e-2)" "unprognostic (1.89e-2)" "unprognostic (5.50e-2)" "unprognostic (1.22e-2)" "unprognostic (1.63e-2)" "unprognostic (1.65e-2)" "unprognostic (3.64e-2)" "unprognostic (5.77e-3)" "unprognostic (1.71e-2)" "unprognostic (7.43e-2)" "unprognostic (1.73e-2)" "unprognostic (1.88e-1)" 11.0 5.0 3.3 5.2 3.9 2.7 8.8 1.0 6.7 11.0 10.1 6.7 3.7 10.4 5.1 7.0 8.7 7.1 5.3 4.6 0.8 6.7 3.8 8.6 5.6 2.5 0.9 6.2 4.1 12.4 4.0 5.2 0.9 8.2 5.3 21.6 5.2 5.5 5.7 8.5 6.0 8.7 0.6 5.7 6.1 7.1 1.5 5.8 10.5 3.8 4.9 8.7 8.7 3.7 7.2 10.9 7.4 5.8 26.6 35.6 9.1 13.9 19.3 10.7 11.8 10.7 6.5 9.0 8.3 16.2 5.6 12.9 10.0 6.8 13.9 4.0 5.5 4.0 11.1 9.2 8.8 0.3 5.9 25.6 4.9 17.6 7.1 11.1 32.4 2.5 2.3 13.8 13.1 8.2 3.0 1.4 5.0 4.2 8.6 18.1 6.5 16.8 5.7 10.9 2.8 6.1 42.6 6.0 4.4 5.5 7.1 0.5 25.4 20.0 9.6 14.2 13.0 3.1 5.2 10.0 12.8 1.4 9.3 0.4 0.2 0.3 0.9 0.3 0.9 0.2 0.4 0.5 0.2 0.2 0.2 1.1 0.9 0.7 0.3 0.1 0.5 0.3 3.3 3.9 1.0 6.7 4.6 0.8 2.5 0.9 0.9 0.6 1.5 3.7 55.9 19.2 11.7 36.6 9.0 38.0 28.0 17.1 70.0 33.2 19.0 25.0 9.2 10.0 10.4 27.6 41.7 9.5 33.7 29.0 3.9 9.7 25.9 20.6 61.3 81.4 10.3 4.8 151.4 24.1 7.9 53.1 20.9 28.7 1.3 15.8 126.7 11.1 6.9 5.0 62.6 16.6 8.2 33.1 29.3 27.5 59.0 12.9 30.2 33.7 8.6 214.1 47.4 30.7 27.9 16.3 32.8 65.1 20.7 40.9 12.7 34.5 10.0 136.7 6.6 26.0 35.6 27.9 15.4 30.7 38.8 3.7 32.8 20.2 19.6 28.7 SNX4 ATG24B ENSG00000114520 "Sorting nexin 4" O95219 3 125446650-125520202 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 163.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005709 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA005709: AB_1080049" "unprognostic (1.11e-1)" "unprognostic (2.08e-1)" "unprognostic (1.91e-2)" "prognostic unfavorable (6.10e-4)" "unprognostic (1.97e-2)" "unprognostic (1.80e-1)" "unprognostic (1.19e-2)" "unprognostic (6.33e-2)" "unprognostic (4.93e-2)" "unprognostic (4.06e-1)" "unprognostic (3.42e-1)" "unprognostic (6.99e-2)" "prognostic favorable (5.01e-5)" "unprognostic (2.40e-1)" "unprognostic (1.03e-1)" "unprognostic (7.13e-3)" "unprognostic (1.05e-1)" 16.7 22.1 11.0 12.7 11.2 16.3 25.3 11.5 16.7 19.9 12.4 24.9 35.8 14.1 13.7 14.9 14.2 19.8 16.5 11.1 12.3 53.8 56.5 18.1 16.3 11.9 11.1 14.9 19.5 18.0 14.4 31.7 12.0 22.7 27.7 9.1 22.4 11.4 18.9 10.2 34.2 13.4 11.8 13.0 21.6 16.1 10.8 21.1 44.9 23.3 17.1 16.8 11.3 14.0 34.8 10.9 34.5 21.8 20.9 17.4 39.1 18.5 17.5 35.9 32.1 23.7 15.5 22.0 21.4 22.5 15.5 18.0 32.4 15.6 42.9 20.6 23.8 35.6 14.5 36.0 24.5 37.8 22.1 22.7 17.0 18.2 14.5 20.0 34.1 31.8 38.6 10.9 27.6 26.2 41.8 25.4 20.2 37.6 13.0 38.2 42.0 40.3 33.0 30.6 36.1 50.9 29.8 38.3 47.4 32.0 37.7 61.3 22.3 18.0 22.9 23.4 21.9 22.1 20.1 60.2 22.0 23.8 27.8 12.4 14.0 25.8 9.7 18.8 13.0 13.8 12.4 11.2 18.3 10.3 15.8 13.8 2.6 17.4 19.1 16.1 15.1 12.0 11.0 11.2 11.5 16.7 11.1 12.3 11.9 11.1 12.0 11.8 10.8 14.0 27.1 28.9 39.4 33.6 24.5 12.1 17.9 21.3 12.5 13.4 27.2 17.1 17.7 37.1 34.1 22.0 0.0 87.2 20.6 39.9 60.7 45.4 21.6 23.8 22.1 24.7 30.0 22.7 46.7 36.6 57.8 26.9 26.0 20.9 31.0 30.9 24.7 75.8 50.9 18.5 44.9 37.0 46.8 27.0 22.6 31.5 22.1 28.3 30.2 31.9 45.7 21.3 34.0 37.7 47.8 42.9 37.9 18.0 26.2 22.5 48.8 163.4 37.1 12.0 13.1 27.8 30.3 33.0 29.8 23.0 11.8 41.2 22.9 27.2 29.6 15.7 SOD1 "ALS, ALS1, IPOA" ENSG00000142168 "Superoxide dismutase 1" P00441 21 31659666-31668931 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antioxidant, Oxidoreductase" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1645.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 3357.9;Proximal tubular cells: 3285.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001401, CAB008670" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 44900000 50000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 15: Liver - Metabolism" "Cluster 16: U-266 - Nucleosome" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Plasma membrane, Cytosol" "CAB008670: AB_1623312, HPA001401: AB_1080132" "unprognostic (1.73e-1)" "unprognostic (1.18e-2)" "unprognostic (4.43e-1)" "unprognostic (6.19e-2)" "unprognostic (1.39e-1)" "unprognostic (9.59e-3)" "unprognostic (8.34e-2)" "unprognostic (2.30e-1)" "unprognostic (3.47e-1)" "unprognostic (5.28e-2)" "unprognostic (9.33e-2)" "unprognostic (1.96e-1)" "unprognostic (1.03e-2)" "unprognostic (1.66e-1)" "unprognostic (1.74e-2)" "unprognostic (1.57e-1)" "unprognostic (3.26e-2)" 257.6 597.1 558.0 118.4 577.4 166.4 233.5 605.2 805.1 206.6 586.6 251.0 360.3 179.5 228.4 221.1 197.1 206.0 477.3 575.1 619.9 483.2 1645.6 153.9 169.6 619.8 604.6 302.1 117.1 210.6 236.7 155.8 653.1 203.9 180.5 248.6 160.5 204.2 428.0 152.1 266.7 136.6 588.1 147.5 210.4 132.1 585.8 165.7 197.4 355.9 151.7 232.1 220.6 634.7 526.8 451.4 309.2 312.8 407.3 282.1 257.8 430.2 258.0 291.3 217.4 593.6 326.0 628.2 441.2 405.8 517.7 186.1 453.3 320.6 239.9 463.3 540.0 1008.2 579.5 866.3 267.4 451.7 363.1 294.8 240.6 406.5 225.2 327.9 331.2 469.0 704.4 773.2 357.4 860.0 489.0 454.5 466.1 830.0 475.4 413.0 622.0 981.4 579.4 320.5 335.9 281.4 805.1 419.4 438.3 279.2 484.3 393.4 387.4 222.9 489.2 304.7 322.0 583.4 1374.2 741.8 455.7 654.3 301.9 204.2 159.7 194.0 313.4 234.0 365.3 427.1 509.2 402.4 212.8 310.1 521.8 412.1 37.8 241.4 465.4 240.6 746.0 474.5 558.0 577.4 605.2 805.1 575.1 619.9 619.8 604.6 653.1 588.1 585.8 634.7 319.8 294.9 175.1 38.2 248.1 491.4 672.7 479.2 319.8 226.6 264.1 352.9 721.0 527.6 294.7 391.8 47.9 703.4 250.2 703.5 1631.7 426.3 277.0 410.7 241.2 261.0 288.4 898.8 39.7 807.3 574.9 365.8 198.8 216.3 220.0 278.9 318.1 3357.9 363.3 282.7 45.5 402.7 366.2 220.0 318.5 952.2 521.9 224.2 419.8 29.0 313.1 598.5 239.0 28.6 68.7 322.8 600.9 528.1 178.2 567.0 1158.3 3285.9 638.3 216.5 440.4 313.6 404.5 211.7 506.3 379.9 349.8 725.9 423.1 470.3 593.6 497.7 SORBS2 "ARGBP2, KIAA0777" ENSG00000154556 "Sorbin and SH3 domain containing 2" O94875 4 185585444-185956652 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 575.3;thyroid gland: 277.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 557.8;Cone photoreceptor cells: 771.5;Excitatory neurons: 397.4;Rod photoreceptor cells: 815.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 241.1;TIME: 133.1;WM-115: 76.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "unprognostic (3.30e-2)" "unprognostic (5.09e-2)" "unprognostic (1.20e-1)" "prognostic favorable (6.07e-5)" "unprognostic (1.61e-2)" "unprognostic (1.09e-1)" "prognostic favorable (1.47e-5)" "unprognostic (1.28e-1)" "unprognostic (1.37e-1)" "unprognostic (1.20e-1)" "unprognostic (8.30e-2)" "unprognostic (1.72e-1)" "prognostic favorable (3.10e-6)" "unprognostic (1.26e-1)" "unprognostic (2.42e-1)" "unprognostic (2.79e-3)" "unprognostic (2.51e-2)" 27.4 166.6 32.3 11.5 62.5 0.1 38.9 0.0 40.3 31.8 14.1 85.9 10.5 17.6 34.3 36.5 37.0 29.0 575.3 38.0 2.1 32.4 126.5 19.2 5.3 16.1 0.9 17.6 117.3 100.5 29.1 69.0 18.2 56.1 25.9 156.1 74.4 62.3 6.9 8.1 16.1 31.6 1.9 26.2 40.5 3.0 2.8 31.1 277.6 12.8 11.3 50.1 16.3 26.7 0.4 0.5 241.1 0.2 33.6 59.4 12.0 0.5 0.2 0.0 0.6 6.8 19.4 0.0 25.8 2.2 1.6 0.0 0.0 9.1 0.2 0.1 3.6 3.8 18.4 16.0 0.0 0.0 0.2 22.0 2.7 37.1 2.9 31.7 44.8 6.7 0.1 0.2 2.7 0.0 0.0 0.7 23.4 0.0 0.0 23.9 0.0 0.2 32.8 5.9 30.2 9.0 0.0 0.1 14.9 23.3 7.3 0.0 133.1 18.2 2.4 0.3 9.4 0.3 0.4 0.3 39.3 0.0 76.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 32.3 62.5 0.0 40.3 38.0 2.1 16.1 0.9 18.2 1.9 2.8 26.7 71.1 22.4 41.4 18.9 2.4 6.5 18.5 44.1 21.6 99.7 81.4 45.6 557.8 228.8 85.5 64.4 771.5 12.8 1.9 8.5 5.9 166.1 3.2 80.8 4.0 69.6 41.9 5.3 397.4 110.1 2.6 30.7 30.1 75.3 2.5 102.4 26.7 206.6 1.6 5.0 247.3 14.0 61.1 4.1 8.0 6.9 5.6 2.5 19.6 150.9 3.1 265.7 12.3 204.1 7.2 57.7 27.1 3.8 5.3 25.8 15.8 25.8 149.3 815.8 118.3 4.4 297.8 0.3 1.4 12.4 5.5 10.9 1.8 13.2 26.8 19.3 SOWAHB ANKRD56 ENSG00000186212 "Sosondowah ankyrin repeat domain family member B" A6NEL2 4 76894152-76898144 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 19.1" "Cell type enhanced" "Detected in some" "Distal tubular cells: 1.9;Gastric mucus-secreting cells: 4.6;Squamous epithelial cells: 2.7;Urothelial cells: 6.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 3.9;BEWO: 8.3;CACO-2: 3.9;OE19: 7.4;RT4: 19.4;T-47d: 5.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA036809, HPA036810" Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli fibrillar center" "HPA036809: AB_10672479, HPA036810: AB_2675327" "unprognostic (2.05e-1)" "unprognostic (2.41e-1)" "unprognostic (1.17e-1)" "unprognostic (1.87e-2)" "unprognostic (1.02e-2)" "unprognostic (1.02e-2)" "unprognostic (3.28e-2)" "unprognostic (2.21e-1)" "unprognostic (1.51e-2)" "unprognostic (3.06e-1)" "unprognostic (2.85e-2)" "unprognostic (1.46e-1)" "prognostic favorable (1.22e-15)" "unprognostic (1.36e-1)" "unprognostic (1.80e-1)" "unprognostic (2.03e-2)" "unprognostic (3.73e-3)" 0.0 0.3 1.2 0.7 1.4 0.0 1.3 0.0 2.8 1.0 0.7 7.7 5.5 0.3 0.8 6.2 1.1 1.3 0.0 1.8 0.1 7.7 19.1 1.6 0.0 0.5 0.0 0.0 5.8 6.9 0.4 0.6 0.6 0.8 6.3 0.2 2.4 2.7 0.0 1.5 8.1 0.2 0.0 0.0 4.6 0.0 0.0 0.2 2.4 0.0 2.3 6.0 2.2 1.1 3.9 0.1 0.3 0.2 0.0 0.0 8.3 0.0 0.0 0.0 0.0 3.9 2.6 0.0 0.1 0.0 0.0 0.2 0.3 0.7 0.0 0.0 0.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.2 7.4 0.0 0.0 0.0 0.0 0.5 19.4 0.1 0.0 0.0 1.7 0.0 0.6 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.4 0.0 2.8 1.8 0.1 0.5 0.0 0.6 0.0 0.0 1.1 0.0 0.0 0.5 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.2 0.0 0.8 0.0 0.2 0.0 0.0 0.2 0.0 1.5 1.9 0.1 0.0 1.0 0.1 0.0 0.0 0.0 0.1 0.5 0.0 0.0 4.6 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.4 0.0 0.0 1.1 1.1 0.9 1.0 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.1 0.0 0.5 6.1 SOX18 ENSG00000203883 "SRY-box transcription factor 18" P35713 20 64047582-64049639 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 78.4" "Group enriched" "Detected in many" 9 "Adipocytes: 370.9;Endothelial cells: 212.4;Hepatic stellate cells: 306.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 20.8;NB-4: 35.8;REH: 8.5;TIME: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073703 Approved Nucleoplasm NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 24: NB-4 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA073703: AB_2686628" "unprognostic (2.51e-1)" "unprognostic (3.23e-1)" "unprognostic (9.98e-3)" "unprognostic (6.30e-2)" "unprognostic (1.07e-1)" "unprognostic (2.88e-2)" "unprognostic (2.71e-2)" "unprognostic (4.35e-3)" "unprognostic (1.62e-1)" "unprognostic (3.45e-2)" "unprognostic (1.33e-3)" "unprognostic (1.76e-1)" "unprognostic (1.13e-3)" "unprognostic (9.63e-3)" "unprognostic (1.41e-1)" "unprognostic (2.46e-1)" "unprognostic (5.40e-2)" 51.8 14.3 8.9 3.1 6.4 0.0 43.1 6.5 6.3 19.5 1.7 16.3 3.1 38.4 0.3 12.0 29.2 3.7 78.4 4.4 5.5 21.4 5.2 29.1 3.1 10.1 8.0 8.0 8.2 1.3 6.6 5.5 9.5 17.6 0.4 0.0 12.6 1.3 13.9 12.2 17.0 1.5 6.7 22.5 15.6 5.6 9.9 0.8 29.0 3.8 0.5 19.7 21.9 5.4 0.0 0.3 0.0 5.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 5.0 0.0 0.0 0.2 0.3 0.0 0.0 0.5 1.0 0.0 3.0 5.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 20.8 0.0 3.7 0.0 0.0 0.7 0.0 35.8 0.1 0.0 0.3 8.5 0.0 0.6 0.0 1.4 0.6 0.6 0.3 0.0 0.5 0.0 0.5 1.8 9.6 0.1 2.6 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 6.4 6.5 6.3 4.4 5.5 10.1 8.0 9.5 6.7 9.9 5.4 370.9 0.0 0.6 0.3 3.7 1.0 0.2 0.0 2.2 0.9 1.9 3.0 8.8 1.5 0.0 1.8 0.0 0.0 1.6 0.1 0.0 0.3 22.1 1.0 11.9 212.4 0.0 2.7 0.0 0.0 0.0 2.5 0.0 0.7 4.5 0.0 306.6 0.6 0.1 0.0 0.0 0.0 0.0 6.0 2.2 4.8 1.2 1.3 1.8 15.9 0.1 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 1.2 0.0 3.6 6.5 32.4 2.5 0.9 1.1 0.3 0.7 2.3 0.0 0.3 SOX9 "CMD1, CMPD1, SRA1" ENSG00000125398 "SRY-box transcription factor 9" P48436 17 72121020-72126416 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.7;salivary gland: 80.1" "Cell type enhanced" "Detected in many" "Astrocytes: 160.0;Basal squamous epithelial cells: 166.8;Breast glandular cells: 141.0;Cholangiocytes: 190.1;Gastric mucus-secreting cells: 144.8;Muller glia cells: 141.3;Squamous epithelial cells: 273.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 78.1;Hep G2: 97.0;OE19: 74.3;U-251 MG: 66.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001758, CAB022456, CAB068240" Enhanced Enhanced Nucleoplasm NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB022456: , CAB068240: AB_2665670, HPA001758: AB_1080067" "unprognostic (6.92e-2)" "unprognostic (1.73e-2)" "unprognostic (4.47e-3)" "unprognostic (4.43e-2)" "unprognostic (2.55e-2)" "unprognostic (7.96e-3)" "unprognostic (4.32e-3)" "prognostic unfavorable (2.07e-4)" "unprognostic (4.87e-2)" "unprognostic (3.31e-1)" "unprognostic (8.92e-3)" "unprognostic (1.21e-1)" "unprognostic (3.26e-3)" "unprognostic (2.77e-3)" "unprognostic (1.15e-1)" "unprognostic (8.88e-2)" "unprognostic (1.21e-2)" 3.1 2.2 54.7 4.4 50.4 0.1 28.0 42.3 58.5 7.4 46.8 17.1 19.7 2.9 0.9 13.7 7.5 13.0 15.8 50.6 49.3 12.7 3.5 3.1 1.1 73.7 72.2 0.3 38.4 0.1 10.3 0.3 48.8 24.8 17.8 15.0 80.1 10.9 2.7 23.3 15.1 1.2 56.9 0.2 40.5 30.7 51.4 0.5 20.2 1.2 4.4 1.9 6.4 49.0 31.1 19.2 38.9 78.1 3.9 1.1 0.1 4.8 4.2 8.2 4.4 27.0 40.8 0.0 2.9 1.1 43.8 31.3 0.0 18.6 7.5 0.0 2.5 0.0 4.2 97.0 0.3 0.0 0.1 0.7 1.6 9.5 9.0 47.0 0.0 0.0 0.0 0.1 11.7 0.4 0.0 0.1 1.5 74.3 29.1 0.0 31.4 0.4 35.2 2.0 1.9 1.9 4.0 4.7 0.1 21.0 16.7 0.2 0.0 15.8 42.0 8.5 66.5 0.0 0.0 0.1 11.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.7 50.4 42.3 58.5 50.6 49.3 73.7 72.2 48.8 56.9 51.4 49.0 1.1 12.8 5.6 160.0 1.9 55.4 88.2 28.9 166.8 3.0 141.0 108.2 13.6 190.1 21.1 36.8 0.0 0.3 2.8 52.1 7.9 55.3 5.1 18.4 0.9 3.2 59.7 0.0 3.1 46.7 0.0 26.0 144.8 21.7 4.5 1.9 0.0 3.4 0.2 0.0 1.5 99.0 24.4 0.0 3.4 14.5 4.4 2.3 12.4 9.4 1.0 141.3 0.0 4.5 11.1 40.8 39.1 0.4 2.8 81.1 17.7 61.0 36.4 6.8 6.6 59.9 14.5 10.2 3.1 273.5 17.8 0.1 2.8 0.1 103.8 77.2 SP140 "LYSP100-A, LYSP100-B" ENSG00000079263 "SP140 nuclear body protein" Q13342 2 230203110-230313215 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 15.6;lymphoid tissue: 55.8" "Cell type enhanced" "Detected in many" "B-cells: 149.9;dendritic cells: 37.4;NK-cells: 50.4;Plasma cells: 77.2;T-cells: 62.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 97.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 31.1;HDLM-2: 52.4;Karpas-707: 25.2;RPMI-8226: 16.3" "Low region specificity" "Detected in all" "HPA006162, HPA067493" Enhanced Approved "Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" "Nucleoli fibrillar center" Mitochondria "HPA006162: AB_1857403, HPA067493: AB_2685851" "unprognostic (8.15e-3)" "unprognostic (2.25e-3)" "unprognostic (3.90e-3)" "unprognostic (5.72e-4)" "unprognostic (5.66e-2)" "unprognostic (3.33e-4)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (6.05e-2)" "unprognostic (1.12e-3)" "unprognostic (3.89e-2)" "unprognostic (2.88e-1)" "unprognostic (1.20e-9)" "unprognostic (9.12e-2)" "unprognostic (8.50e-2)" "unprognostic (3.66e-1)" "unprognostic (9.30e-3)" 1.7 0.8 0.7 25.0 0.8 6.6 1.2 0.8 1.6 0.6 1.0 3.5 2.9 0.9 0.8 0.9 0.7 2.9 0.6 0.8 1.1 0.9 1.6 4.4 54.6 1.8 1.2 0.4 0.3 0.2 0.6 1.2 1.5 0.9 3.9 1.0 2.6 0.5 0.2 1.6 15.6 1.0 1.3 27.8 5.1 1.5 2.1 6.8 1.3 0.1 55.8 4.3 0.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 2.4 0.0 0.3 31.1 0.0 0.0 5.2 0.0 0.0 0.1 1.8 52.4 0.0 0.0 0.0 0.6 0.2 4.4 0.1 0.5 0.0 0.5 0.6 0.4 0.0 0.3 0.0 25.2 0.6 0.0 0.0 1.5 1.3 0.0 0.0 0.1 2.8 16.3 8.8 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.6 0.1 0.3 1.3 0.0 0.0 9.2 4.0 1.1 2.2 0.7 0.0 0.1 3.5 12.0 23.1 7.3 25.6 97.5 22.8 25.3 8.3 71.0 11.5 15.0 33.4 15.1 10.6 0.5 22.5 10.6 0.7 0.8 0.8 1.6 0.8 1.1 1.8 1.2 1.5 1.3 2.1 1.5 1.6 0.0 2.3 3.9 149.9 0.9 0.0 0.2 0.0 0.7 0.3 0.5 0.5 0.0 0.8 0.0 8.4 0.1 37.4 0.1 0.0 0.0 17.2 0.5 0.2 1.1 0.0 9.7 5.0 0.0 0.2 0.8 1.5 0.1 0.0 0.2 2.2 0.9 11.4 0.0 5.0 0.1 0.0 8.4 8.6 4.8 0.0 13.2 7.2 26.2 13.7 0.5 50.4 2.5 2.8 0.1 0.1 1.2 77.2 0.1 0.0 0.4 2.4 1.7 0.0 0.2 1.0 1.2 0.4 0.7 1.1 0.3 62.1 0.3 0.2 0.2 SP5 ENSG00000204335 "Sp5 transcription factor" Q6BEB4 2 170715337-170718078 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 8.8" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 2.8;Cardiomyocytes: 3.1;Distal tubular cells: 3.9;Endometrial stromal cells: 7.1;Fibroblasts: 4.4;Intestinal goblet cells: 4.3;Spermatogonia: 3.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "Hep G2: 122.1" "Region enhanced" "Detected in single" "cerebellum: 1.1" "Low region specificity" "Detected in some" HPA074123 Approved Nucleoplasm,Nucleoli NA NA "Cluster 31: Skin - Epidermis development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" Nucleoli Nucleoplasm "HPA074123: AB_2686664" "unprognostic (1.16e-2)" "unprognostic (6.99e-2)" "unprognostic (3.41e-2)" "unprognostic (2.10e-2)" "unprognostic (1.14e-1)" "unprognostic (9.52e-3)" "unprognostic (1.45e-1)" "unprognostic (4.60e-2)" "unprognostic (4.77e-1)" "unprognostic (8.97e-3)" "unprognostic (1.79e-2)" "unprognostic (3.09e-2)" "unprognostic (2.06e-8)" "unprognostic (8.05e-3)" "unprognostic (2.49e-1)" "unprognostic (2.41e-2)" "unprognostic (2.17e-1)" 2.5 1.2 0.5 0.2 0.5 0.0 1.4 2.2 0.3 8.8 0.5 1.5 1.0 3.7 0.4 1.2 1.2 0.2 0.2 0.2 1.4 0.2 2.1 0.5 0.2 0.3 1.4 0.4 0.4 0.3 0.1 0.2 0.2 1.7 0.2 0.0 1.5 0.2 0.2 4.6 1.4 0.1 0.0 0.0 3.1 0.8 1.8 0.1 0.1 0.0 0.8 1.5 2.2 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 27.7 0.1 0.0 0.5 0.0 0.5 1.5 0.3 0.0 0.0 3.5 0.3 0.4 0.1 122.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 2.0 2.3 0.0 0.0 0.0 0.1 0.0 0.1 0.3 4.2 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 2.2 0.3 0.2 1.4 0.3 1.4 0.2 0.0 1.8 0.2 0.2 0.0 0.0 0.3 0.0 0.8 0.1 0.0 2.8 0.0 0.2 0.3 3.1 0.0 0.0 1.8 0.0 1.5 0.1 0.3 3.9 0.0 0.2 2.3 7.1 0.5 0.0 0.0 0.0 0.0 0.0 4.4 0.0 1.3 0.0 0.0 0.0 2.5 0.2 0.0 0.4 4.3 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.4 0.4 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.3 3.7 0.2 0.1 0.3 0.2 0.0 1.6 0.0 SPAAR "LINC00961, SPAR" ENSG00000235387 "Small regulatory polypeptide of amino acid response" A0A1B0GVQ0 9 35909490-35937153 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 12.4;breast: 10.8" "Cell type enriched" "Detected in some" 7 "Adipocytes: 42.3" "Cancer enhanced" "Detected in many" "renal cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "HUVEC TERT2: 34.0;TIME: 40.1" "Not detected" "Not detected" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (3.17e-1)" "unprognostic (2.19e-2)" "unprognostic (1.91e-2)" "unprognostic (7.00e-3)" "unprognostic (4.23e-2)" "unprognostic (2.61e-3)" "unprognostic (6.95e-2)" "unprognostic (1.00e-1)" "unprognostic (3.40e-3)" "unprognostic (3.17e-1)" "unprognostic (1.01e-1)" "unprognostic (7.72e-2)" "unprognostic (7.12e-3)" "unprognostic (1.67e-2)" "unprognostic (3.04e-1)" "unprognostic (1.27e-1)" "unprognostic (3.22e-1)" 12.4 1.2 2.9 0.6 2.5 0.0 10.8 2.2 3.3 0.7 1.1 1.2 0.3 1.2 0.1 0.5 1.2 0.6 8.9 2.3 2.2 4.2 0.8 3.2 0.4 3.0 2.6 0.7 0.5 0.5 0.6 4.7 3.1 1.0 0.4 1.4 0.7 0.5 3.1 0.9 0.9 0.6 2.3 0.7 0.9 7.5 3.3 0.2 1.9 1.8 0.0 1.5 0.8 2.4 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.6 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.4 0.0 0.0 0.4 0.1 0.2 0.0 0.0 34.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 40.1 0.0 0.8 2.7 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.5 2.2 3.3 2.3 2.2 3.0 2.6 3.1 2.3 3.3 2.4 42.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 5.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 SPCS1 "HSPC033, SPC1, SPC12, YJR010C-A" ENSG00000114902 "Signal peptidase complex subunit 1" Q9Y6A9 3 52704955-52711148 "Metabolic proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1177.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046091, HPA055273" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 16: U-266 - Nucleosome" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "HPA046091: AB_10959614, HPA055273: AB_2682768" "unprognostic (5.47e-2)" "unprognostic (4.04e-1)" "prognostic favorable (9.28e-4)" "unprognostic (5.93e-2)" "unprognostic (6.88e-2)" "unprognostic (1.10e-2)" "unprognostic (3.22e-1)" "unprognostic (1.60e-1)" "unprognostic (1.91e-1)" "unprognostic (5.56e-2)" "unprognostic (3.89e-1)" "unprognostic (1.15e-1)" "prognostic favorable (2.90e-4)" "unprognostic (5.96e-2)" "unprognostic (1.80e-1)" "unprognostic (3.58e-1)" "unprognostic (3.09e-2)" 95.3 154.7 75.1 64.1 76.6 61.3 100.5 80.7 101.1 97.4 88.7 110.1 94.8 101.0 110.8 117.0 92.1 48.4 119.7 75.4 83.9 137.3 172.8 87.8 71.2 82.3 80.5 91.1 231.2 89.5 141.1 59.4 82.1 96.3 84.7 124.6 145.2 79.1 142.2 109.0 103.9 53.0 81.7 105.6 151.1 153.2 81.4 66.6 113.2 49.7 87.1 103.0 94.7 84.9 114.6 102.2 113.4 139.3 164.9 134.4 157.2 157.6 144.5 139.4 128.4 108.1 171.0 114.6 65.7 145.4 142.5 110.2 109.9 142.5 149.1 154.3 115.8 138.6 169.2 164.6 175.1 213.3 229.1 104.7 190.5 148.5 174.4 130.5 117.4 147.5 118.8 418.0 151.8 105.5 168.8 207.2 195.8 317.2 203.9 67.9 95.7 608.6 232.7 148.3 73.6 157.4 148.7 178.1 224.2 102.4 188.1 248.1 106.2 127.3 119.1 226.3 192.1 406.2 654.1 169.8 196.5 209.4 169.8 292.7 129.9 258.2 131.1 137.0 155.1 202.0 158.5 144.2 143.9 149.3 146.8 152.1 100.1 119.6 152.5 620.5 177.1 253.8 75.1 76.6 80.7 101.1 75.4 83.9 82.3 80.5 82.1 81.7 81.4 84.9 172.5 64.1 104.2 23.8 282.3 156.5 227.9 470.7 136.1 465.4 289.0 351.0 148.7 221.6 283.6 310.8 118.9 373.5 488.1 195.2 361.9 353.8 597.8 286.4 180.8 157.6 167.7 143.9 27.1 339.4 399.8 181.9 119.8 181.5 211.6 138.7 131.4 301.8 311.0 102.6 34.4 291.3 325.5 202.9 189.9 1177.6 216.3 192.5 380.6 13.1 321.9 296.9 213.1 21.1 53.2 274.8 274.1 191.8 888.8 295.0 405.5 665.1 374.1 251.3 164.3 152.6 335.5 746.4 504.5 195.8 184.4 351.2 220.8 283.6 267.7 285.3 SPIC "MGC40611, SPI-C" ENSG00000166211 "Spi-C transcription factor" Q8N5J4 12 101475336-101486997 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 30.8" "Group enriched" "Detected in some" 8 "Kupffer cells: 16.7;Macrophages: 11.0" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 1.1" "Lineage enriched" "Detected in single" 8 "monocytes: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (9.82e-2)" "unprognostic (2.43e-2)" "unprognostic (9.03e-3)" "unprognostic (2.51e-1)" "unprognostic (4.85e-2)" "unprognostic (5.78e-2)" "unprognostic (5.30e-2)" "unprognostic (1.77e-1)" 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 30.8 0.1 0.1 0.0 1.2 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.3 0.0 0.2 0.0 0.0 16.7 0.0 0.0 0.0 11.0 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 SPICE1 "CCDC52, SPICE" ENSG00000163611 "Spindle and centriole associated protein 1" Q8N0Z3 3 113442718-113515187 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA064843 Approved Supported Centrosome NA NA "Cluster 46: Basophils - DNA binding" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Centrosome "HPA064843: AB_2685367" "unprognostic (2.66e-1)" "unprognostic (1.27e-2)" "unprognostic (1.12e-1)" "unprognostic (4.95e-3)" "unprognostic (2.69e-1)" "unprognostic (1.01e-1)" "unprognostic (4.99e-3)" "unprognostic (1.17e-1)" "unprognostic (6.30e-2)" "unprognostic (2.24e-1)" "unprognostic (1.17e-3)" "unprognostic (1.89e-2)" "unprognostic (4.75e-3)" "unprognostic (6.53e-2)" "unprognostic (4.47e-1)" "unprognostic (3.64e-3)" "unprognostic (2.95e-2)" 4.4 3.8 2.1 4.6 2.3 4.1 7.4 3.2 2.9 8.5 3.4 6.7 4.1 8.6 4.9 6.9 8.0 7.7 4.3 2.4 2.4 4.6 4.1 4.7 4.1 2.2 2.1 7.8 6.3 6.4 8.9 5.5 2.1 6.4 6.6 7.7 8.6 4.9 2.6 6.0 5.3 6.7 1.4 4.2 6.8 7.1 1.9 8.3 6.8 2.3 5.5 6.1 7.2 3.1 17.0 10.4 12.1 10.6 7.5 9.2 7.6 8.2 6.3 10.9 13.6 9.2 9.4 9.9 11.6 7.2 10.7 16.0 6.3 8.0 14.7 5.9 2.8 9.0 9.3 6.1 4.5 18.0 6.8 7.5 7.9 11.3 4.6 9.6 8.0 18.0 5.8 8.2 3.8 17.7 15.6 7.0 13.0 13.4 11.5 10.8 10.3 8.8 4.0 10.7 6.2 10.8 8.7 10.3 4.8 13.4 10.2 7.2 8.0 5.5 8.8 5.1 7.5 7.9 5.8 16.7 11.0 10.5 8.2 3.6 4.1 1.5 3.2 3.0 5.2 5.6 5.0 4.0 3.1 6.1 7.0 5.2 2.1 2.7 2.9 9.7 2.6 2.0 2.1 2.3 3.2 2.9 2.4 2.4 2.2 2.1 2.1 1.4 1.9 3.1 6.7 0.0 4.2 14.4 12.0 6.8 7.9 5.4 9.1 6.4 9.4 5.8 2.5 5.7 5.6 5.5 8.4 4.7 3.5 8.0 0.0 5.4 6.5 22.8 11.9 4.7 3.6 9.9 20.2 4.5 5.9 7.4 16.3 12.7 1.3 10.1 3.3 5.2 4.4 3.3 6.8 10.6 6.1 2.5 3.9 3.5 9.9 4.1 0.0 15.9 2.3 7.9 1.0 16.1 14.4 5.6 3.6 3.4 13.9 4.1 3.9 4.2 15.3 25.0 6.6 6.2 5.4 20.9 16.9 7.7 7.7 3.4 7.5 6.2 7.4 8.5 SPNS3 "MGC29671, SLC62A3" ENSG00000182557 "Sphingolipid transporter 3 (putative)" Q6ZMD2 17 4433940-4488208 "Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "bone marrow: 31.2" "Cell type enhanced" "Detected in many" "dendritic cells: 30.9;Langerhans cells: 16.4;Proximal tubular cells: 51.8;T-cells: 23.7" "Cancer enhanced" "Detected in many" "renal cancer: 2.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "eosinophil: 354.8;plasmacytoid DC: 127.7" "Group enriched" "Detected in many" 37 "dendritic cells: 127.7;granulocytes: 354.8" "Group enriched" "Detected in some" 4 "JURKAT: 29.5;NB-4: 46.8;THP-1: 35.5;U-937: 22.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA023928 Uncertain NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA023928: AB_1844393" "unprognostic (4.39e-2)" "unprognostic (8.10e-5)" "unprognostic (2.37e-1)" "unprognostic (1.27e-1)" "unprognostic (1.51e-1)" "unprognostic (1.94e-4)" "unprognostic (2.86e-2)" "unprognostic (1.96e-2)" "unprognostic (1.81e-2)" "unprognostic (6.46e-2)" "unprognostic (1.37e-1)" "unprognostic (3.96e-2)" "prognostic unfavorable (8.09e-4)" "unprognostic (6.18e-2)" "unprognostic (6.57e-2)" "unprognostic (4.13e-2)" "unprognostic (9.69e-2)" 0.1 0.1 0.3 1.4 0.2 31.2 0.3 0.4 0.4 0.2 0.0 0.2 0.4 0.0 0.0 0.1 0.7 0.7 0.2 0.2 0.7 0.2 0.1 0.2 2.0 0.8 0.4 0.0 0.3 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.9 0.3 0.0 0.3 0.7 0.1 0.6 2.1 0.3 0.0 0.5 3.6 0.0 0.0 1.1 0.3 0.0 0.7 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.5 0.0 2.4 0.0 0.0 8.1 46.8 0.0 0.2 0.0 0.1 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.1 0.0 0.1 0.0 0.1 6.6 0.0 22.1 0.0 0.3 6.5 354.8 1.1 1.3 0.7 0.2 0.0 1.5 47.6 0.3 0.4 1.7 1.0 0.2 0.1 127.7 0.0 6.2 0.3 0.2 0.4 0.4 0.2 0.7 0.8 0.4 0.5 0.6 0.5 0.7 0.5 3.2 1.1 0.0 4.3 1.3 0.1 0.4 0.0 0.0 1.0 0.8 0.8 1.5 1.6 0.0 0.0 0.3 30.9 0.5 3.9 2.0 1.1 0.8 0.0 0.6 0.0 4.8 0.9 0.0 6.1 0.3 2.0 0.1 0.0 0.0 0.7 0.3 1.4 0.0 0.8 2.1 6.1 5.5 16.4 2.6 0.0 9.8 1.8 3.7 6.7 0.0 11.3 0.0 0.1 1.1 1.4 0.0 0.6 0.5 10.9 51.8 5.0 0.0 0.0 0.3 0.6 0.0 0.3 0.2 0.4 0.3 23.7 0.0 2.5 2.1 SPOCK2 "KIAA0275, testican-2" ENSG00000107742 "SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2" Q92563 10 72059034-72089032 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 220.1;lymphoid tissue: 114.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 288.4;Bipolar cells: 116.5;dendritic cells: 86.4;Inhibitory neurons: 81.1;Microglial cells: 75.9;NK-cells: 90.6;T-cells: 195.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 117.5;MAIT T-cell: 198.8;memory CD4 T-cell: 115.9;memory CD8 T-cell: 93.5;naive CD4 T-cell: 87.8;naive CD8 T-cell: 89.4;T-reg: 174.3" "Lineage enriched" "Detected in all" 8 "T-cells: 198.8" "Group enriched" "Detected in some" 7 "Hep G2: 50.2;SCLC-21H: 68.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044605 Enhanced "Secreted to blood" NA NA 34000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 24: Non-specific - Transcription regulation" "HPA044605: AB_10965991" "prognostic favorable (4.05e-4)" "unprognostic (3.11e-3)" "unprognostic (2.92e-2)" "unprognostic (2.29e-1)" "unprognostic (2.77e-2)" "prognostic favorable (1.95e-5)" "unprognostic (4.18e-2)" "unprognostic (9.04e-2)" "prognostic favorable (4.72e-4)" "prognostic unfavorable (7.19e-4)" "unprognostic (4.53e-3)" "unprognostic (2.29e-1)" "unprognostic (1.46e-3)" "unprognostic (5.59e-2)" "unprognostic (5.49e-2)" "unprognostic (3.19e-3)" "unprognostic (2.24e-2)" 9.4 46.6 152.6 44.5 108.0 58.1 3.8 160.4 143.2 4.2 2.8 7.6 9.2 4.0 3.1 3.3 6.2 15.3 10.0 117.4 150.1 68.0 2.7 86.5 67.3 212.1 157.7 7.1 1.6 2.0 44.0 3.4 220.1 4.7 5.4 33.4 3.3 5.6 5.1 1.8 32.3 4.4 127.9 29.1 13.6 25.1 207.3 114.4 10.4 6.7 45.3 9.9 3.8 95.6 0.2 0.4 0.3 0.6 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 8.2 0.3 1.4 0.0 0.0 0.9 0.0 0.0 0.0 0.5 0.8 0.2 1.4 50.2 1.6 0.4 1.2 0.1 0.4 0.0 0.0 0.2 0.1 2.7 0.1 0.8 0.0 0.3 0.9 0.3 0.1 0.0 0.2 0.2 0.3 0.1 0.0 0.3 68.2 4.1 0.1 1.5 0.4 0.3 0.0 1.9 0.2 0.0 0.3 0.3 0.1 0.7 1.7 7.3 0.3 0.1 0.2 0.6 0.4 0.2 117.5 1.2 198.8 23.6 115.9 93.5 0.3 18.3 87.8 89.4 13.5 14.4 0.4 3.5 174.3 48.4 152.6 108.0 160.4 143.2 117.4 150.1 212.1 157.7 220.1 127.9 207.3 95.6 17.3 288.4 10.0 51.9 54.6 3.8 0.4 2.1 0.0 116.5 1.9 2.0 3.1 1.5 4.1 14.7 6.2 0.1 86.4 2.4 0.0 3.6 8.1 2.5 1.0 29.9 4.9 3.6 39.6 0.8 0.1 8.4 3.6 1.0 3.8 0.2 7.9 0.4 0.2 3.3 81.1 1.3 2.0 1.6 7.9 10.5 5.3 5.5 5.4 75.9 4.1 5.0 90.6 28.6 8.3 0.0 4.4 6.0 34.2 0.5 0.1 0.5 2.4 17.6 0.0 17.9 2.4 6.3 1.1 0.5 4.4 0.4 195.1 0.8 0.7 0.3 SPRED1 "FLJ33903, PPP1R147" ENSG00000166068 "Sprouty related EVH1 domain containing 1" Q7Z699 15 38252836-38357249 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 173.7;Excitatory neurons: 163.4;Microglial cells: 199.5;Oligodendrocyte precursor cells: 277.9;Oligodendrocytes: 146.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.4" "Lineage enriched" "Detected in single" 4 "monocytes: 1.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042193, HPA061805" Approved Supported Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA042193: AB_10794079, HPA061805: AB_2684617" "unprognostic (1.30e-1)" "unprognostic (1.28e-2)" "unprognostic (2.46e-1)" "prognostic favorable (7.08e-4)" "unprognostic (1.20e-1)" "unprognostic (2.38e-1)" "unprognostic (1.21e-3)" "unprognostic (5.71e-2)" "unprognostic (3.84e-2)" "unprognostic (2.81e-3)" "unprognostic (9.27e-3)" "unprognostic (3.33e-1)" "prognostic unfavorable (7.37e-5)" "prognostic unfavorable (8.29e-5)" "unprognostic (6.04e-2)" "unprognostic (5.77e-2)" "unprognostic (1.01e-1)" 12.7 8.2 16.0 8.8 20.3 0.7 10.9 14.7 20.6 11.5 7.1 11.4 8.2 10.9 5.7 6.1 6.9 12.8 7.3 16.5 16.3 9.1 5.6 17.4 7.1 18.9 19.6 7.9 4.5 6.8 4.0 14.0 16.2 7.2 10.9 7.5 5.6 8.6 2.6 6.1 8.4 9.5 15.6 9.0 10.3 8.2 17.9 4.4 31.1 8.0 4.9 13.2 6.8 18.3 11.0 8.2 59.0 11.3 21.4 39.0 4.8 25.1 24.7 13.1 16.2 7.6 8.7 0.1 9.0 21.7 9.5 8.6 6.2 17.3 26.2 1.5 2.0 13.0 5.2 7.3 26.3 7.1 34.6 25.5 8.5 25.5 23.4 33.6 10.7 6.5 11.7 12.1 32.2 2.9 2.6 5.2 12.0 37.6 22.0 0.0 13.3 7.3 21.2 16.9 2.9 13.0 7.2 3.5 26.7 9.3 2.8 1.7 18.2 32.0 15.7 19.7 15.4 10.1 7.1 16.7 22.5 2.8 52.1 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 16.0 20.3 14.7 20.6 16.5 16.3 18.9 19.6 16.2 15.6 17.9 18.3 26.4 99.3 26.9 173.7 2.5 28.3 24.6 9.4 45.5 12.6 17.2 20.8 7.2 28.6 12.6 1.8 6.2 1.3 1.5 15.7 1.9 9.5 40.3 12.0 29.4 28.2 6.7 4.6 163.4 4.9 0.9 33.0 17.3 14.8 41.8 5.4 26.7 4.1 57.8 5.0 100.0 21.2 6.1 48.2 24.6 9.6 21.8 38.7 28.4 199.5 7.3 25.4 0.0 277.9 146.9 15.1 7.8 30.5 1.6 12.7 6.6 12.8 11.4 5.2 6.6 44.4 44.1 8.0 5.0 18.1 9.7 1.4 2.4 21.4 15.3 14.7 SPRY1 hSPRY1 ENSG00000164056 "Sprouty RTK signaling antagonist 1" O43609 4 123396795-123403760 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 238.1" "Cell type enhanced" "Detected in many" "Adipocytes: 771.3;Endothelial cells: 352.8;Fibroblasts: 222.3;Leydig cells: 448.0;Skeletal myocytes: 245.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 61.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 95.4;AN3-CA: 194.1;ASC diff: 76.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013538, HPA051369, HPA070554" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Cytosol" Nucleoplasm "CAB013538: AB_2533452, HPA051369: AB_2681457, HPA070554: AB_2686280" "unprognostic (1.27e-1)" "unprognostic (9.08e-2)" "unprognostic (2.06e-1)" "unprognostic (7.15e-2)" "unprognostic (5.33e-2)" "unprognostic (2.19e-2)" "unprognostic (1.36e-1)" "unprognostic (9.43e-2)" "unprognostic (6.99e-2)" "unprognostic (4.32e-1)" "unprognostic (4.06e-1)" "unprognostic (3.11e-2)" "unprognostic (8.77e-3)" "unprognostic (1.21e-3)" "unprognostic (4.48e-2)" "unprognostic (1.54e-2)" "unprognostic (1.27e-1)" 238.1 38.4 6.5 22.3 7.9 22.7 154.3 7.6 9.0 71.9 26.6 46.6 15.7 40.9 24.1 42.5 81.2 83.8 73.1 7.5 8.4 35.6 21.5 58.3 13.0 5.5 5.4 30.0 31.8 37.4 27.3 49.6 5.8 52.0 27.5 19.0 45.2 24.7 49.9 79.8 25.2 57.7 5.6 17.0 35.1 10.2 7.6 29.2 92.7 49.9 10.1 74.4 71.0 6.0 6.3 1.8 95.4 194.1 76.5 51.6 6.4 0.4 4.9 0.3 2.0 5.8 10.3 0.0 42.4 2.9 0.4 1.2 2.6 4.6 0.7 0.1 10.0 2.2 0.0 31.0 21.7 14.2 0.1 21.1 2.5 0.7 2.1 10.5 8.1 2.2 1.7 1.9 4.7 0.7 16.4 34.8 22.8 22.6 32.0 7.1 10.3 0.2 13.2 14.5 14.5 12.3 0.1 19.4 19.6 10.1 1.9 0.0 20.2 1.2 0.2 0.4 2.9 1.0 0.1 0.2 1.4 2.6 3.2 0.1 0.4 6.5 1.1 0.2 33.1 29.8 4.0 9.2 0.1 61.2 5.7 6.4 0.4 14.2 0.1 1.7 0.0 2.0 6.5 7.9 7.6 9.0 7.5 8.4 5.5 5.4 5.8 5.6 7.6 6.0 771.3 28.9 28.3 14.4 16.2 49.6 17.3 37.3 68.9 86.2 22.8 69.6 16.9 32.9 20.6 27.6 33.3 12.7 21.6 10.4 80.3 5.0 2.5 45.9 41.9 352.8 26.5 5.7 5.0 10.9 1.7 222.3 8.2 67.4 9.5 0.2 166.3 5.9 10.1 6.7 2.2 15.0 14.2 15.3 37.9 10.5 448.0 17.1 46.2 5.6 0.7 158.3 0.0 7.5 0.3 7.0 6.3 57.9 6.1 16.8 8.1 38.7 11.7 84.5 151.2 245.0 81.6 6.2 9.6 37.0 43.3 3.1 57.3 1.8 17.9 13.5 SPRYD4 DKFZp686N0877 ENSG00000176422 "SPRY domain containing 4" Q8WW59 12 56468578-56479708 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 20.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 147.2;Proximal tubular cells: 101.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053469 Uncertain Approved Nucleoplasm NA NA 7500 "Cluster 11: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA053469: AB_2682162" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (8.00e-2)" "prognostic unfavorable (8.85e-5)" "unprognostic (7.76e-2)" "unprognostic (1.20e-1)" "unprognostic (3.06e-3)" "prognostic favorable (4.52e-4)" "unprognostic (5.59e-3)" "unprognostic (1.19e-2)" "unprognostic (3.14e-2)" "unprognostic (9.98e-2)" "unprognostic (1.27e-3)" "unprognostic (1.81e-1)" "unprognostic (1.69e-1)" "unprognostic (3.44e-1)" "unprognostic (1.14e-1)" 1.5 3.7 1.6 1.6 1.4 2.8 3.1 3.2 1.9 2.0 0.7 2.5 2.0 2.0 3.0 3.1 2.0 1.5 3.3 1.4 1.6 3.7 20.5 1.4 1.8 0.8 0.8 2.4 6.0 2.5 3.7 1.2 1.0 2.6 3.2 3.4 2.7 1.7 4.1 2.4 2.2 1.7 0.5 2.3 2.5 1.5 1.3 1.4 2.7 5.1 1.7 2.3 2.1 1.2 2.1 2.7 2.3 1.8 2.0 1.3 3.1 1.7 1.7 3.5 2.1 2.5 3.6 2.6 2.2 2.2 2.4 3.5 2.0 2.9 2.2 1.3 4.1 3.8 3.1 3.8 1.9 2.6 3.7 2.9 1.9 2.5 2.1 1.9 3.6 1.8 2.1 11.0 3.0 3.4 1.3 1.9 1.5 2.4 3.1 1.6 1.7 5.4 3.8 2.6 2.3 1.1 3.3 3.9 2.6 1.4 6.6 0.8 1.7 1.5 2.8 2.2 1.4 1.8 1.1 0.9 1.2 2.2 1.9 1.0 1.0 0.5 0.7 0.7 0.8 1.0 0.7 0.7 0.9 1.0 0.7 0.7 0.7 1.2 0.9 1.3 0.3 0.7 1.6 1.4 3.2 1.9 1.4 1.6 0.8 0.8 1.0 0.5 1.3 1.2 4.4 0.0 7.4 2.0 7.9 4.8 16.2 24.8 10.2 13.2 14.1 12.7 17.7 18.6 16.2 22.0 16.7 38.3 5.8 17.3 54.8 26.6 1.4 4.0 7.5 8.9 17.5 19.1 0.9 21.4 24.3 8.1 14.8 9.8 10.2 10.7 10.0 147.2 20.8 16.8 1.6 14.6 28.5 12.2 2.3 1.1 9.0 6.4 5.4 1.9 11.1 10.2 8.2 2.0 2.2 18.5 10.1 10.5 6.3 10.8 19.5 101.5 5.9 17.8 0.0 8.1 8.6 5.1 10.2 22.2 5.3 36.0 4.4 30.2 16.4 19.8 SPSB4 SSB-4 ENSG00000175093 "SplA/ryanodine receptor domain and SOCS box containing 4" Q96A44 3 141051347-141148611 "Predicted intracellular proteins" "Biological rhythms, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 2.9;pancreas: 7.0;pituitary gland: 3.0;testis: 2.9" "Group enriched" "Detected in some" 4 "Early spermatids: 23.6;Late spermatids: 11.7;Oligodendrocyte precursor cells: 41.7;Spermatocytes: 22.1" "Group enriched" "Detected in some" 5 "glioma: 4.6;testis cancer: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 12.5;NTERA-2: 3.5;RH-30: 4.2;SH-SY5Y: 3.6;U-2 OS: 2.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA062793 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Golgi apparatus" "HPA062793: AB_2732689" "unprognostic (5.07e-1)" "unprognostic (1.54e-1)" "unprognostic (1.12e-1)" "unprognostic (1.23e-3)" "prognostic favorable (3.72e-4)" "unprognostic (7.49e-2)" "unprognostic (6.58e-2)" "unprognostic (1.76e-1)" "unprognostic (8.48e-2)" "unprognostic (2.47e-1)" "unprognostic (1.15e-1)" "unprognostic (2.36e-1)" "unprognostic (1.06e-2)" "unprognostic (1.47e-3)" "unprognostic (2.30e-2)" "unprognostic (2.46e-4)" "unprognostic (9.80e-3)" 0.3 0.3 0.5 0.0 0.9 0.0 0.1 0.8 1.2 0.0 2.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.3 2.0 0.3 0.0 0.4 0.0 2.8 2.1 0.0 7.0 0.2 3.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.0 1.5 1.1 0.0 2.9 1.1 0.2 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.0 12.5 0.2 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.4 0.9 0.0 3.5 0.0 0.0 0.0 4.2 0.6 0.0 0.0 1.1 3.6 0.0 0.0 0.0 2.0 0.2 0.3 0.0 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.9 0.8 1.2 0.3 2.0 2.8 2.1 1.6 1.5 1.1 0.9 0.4 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.9 0.0 0.1 4.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 23.6 0.0 0.1 0.1 0.0 0.0 2.8 0.5 0.0 3.2 0.0 0.0 0.0 0.4 0.4 0.1 0.2 0.0 5.6 0.0 0.0 5.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.7 0.3 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.4 22.1 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 SPTBN2 SCA5 ENSG00000173898 "Spectrin beta, non-erythrocytic 2" O15020 11 66682497-66729226 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.6;skin 1: 85.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 86.5;Cone photoreceptor cells: 104.3;Early spermatids: 30.9;Late spermatids: 77.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 45.6;NTERA-2: 49.1;SCLC-21H: 49.9;SK-BR-3: 52.3;T-47d: 67.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009844, HPA039293, HPA043529" Enhanced Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" Vesicles "CAB009844: AB_2194521, HPA039293: AB_2676430, HPA043529: AB_2678531" "unprognostic (9.34e-2)" "unprognostic (5.71e-2)" "unprognostic (4.89e-2)" "unprognostic (3.41e-3)" "unprognostic (4.91e-1)" "unprognostic (6.05e-3)" "unprognostic (4.45e-2)" "unprognostic (1.38e-2)" "unprognostic (7.25e-2)" "unprognostic (1.67e-2)" "prognostic unfavorable (3.14e-5)" "unprognostic (1.64e-1)" "unprognostic (1.05e-3)" "unprognostic (1.34e-1)" "unprognostic (1.84e-1)" "unprognostic (3.99e-2)" "unprognostic (1.00e-3)" 1.3 14.4 26.8 1.0 32.6 2.3 7.7 29.7 73.6 14.3 0.0 0.9 0.9 1.7 1.2 39.8 3.7 1.7 1.4 38.8 0.3 37.5 23.3 1.1 0.2 4.8 0.9 0.9 16.7 13.1 16.4 0.4 3.2 12.4 0.7 14.7 29.6 4.7 0.5 85.5 1.0 1.1 0.0 0.9 2.9 52.8 4.6 1.0 0.3 0.1 6.7 1.6 16.5 24.2 20.5 7.4 3.4 0.3 0.1 0.0 0.6 0.3 0.1 0.1 0.0 4.8 28.2 0.2 3.7 0.0 0.7 16.9 25.2 2.4 0.0 0.1 10.4 0.1 45.6 3.0 0.8 7.3 0.6 0.2 11.5 0.0 7.4 4.2 6.3 5.2 7.3 0.1 0.1 35.2 6.3 3.5 49.1 28.7 21.1 23.8 2.8 14.7 9.6 4.8 49.9 29.4 14.0 52.3 3.2 2.7 67.2 2.4 1.4 0.1 8.6 1.3 11.5 0.7 3.0 14.7 0.1 0.1 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 26.8 32.6 29.7 73.6 38.8 0.3 4.8 0.9 3.2 0.0 4.6 24.2 0.7 3.2 1.1 4.9 0.3 3.7 2.7 3.2 2.8 11.0 4.7 4.6 1.8 1.5 4.6 86.5 104.3 0.9 0.0 0.6 0.0 2.6 30.9 3.6 1.8 1.1 3.0 7.2 29.3 10.0 0.3 0.8 1.5 3.6 0.0 1.4 1.4 24.7 0.1 0.0 20.7 1.6 0.0 0.3 0.7 77.6 1.8 0.1 0.0 2.8 0.6 1.6 0.0 7.5 4.6 7.5 0.2 1.5 0.8 3.2 0.2 1.3 3.5 21.3 0.0 0.2 0.5 8.5 9.4 14.6 12.5 0.3 0.2 0.1 0.8 1.7 SRGN "PPG, PRG, PRG1" ENSG00000122862 Serglycin P10124 10 69088103-69104805 "Plasma proteins, Predicted secreted proteins" "Apoptosis, Biomineralization" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "bone marrow: 8096.7" "Cell type enhanced" "Detected in many" "dendritic cells: 2922.2;granulocytes: 2343.1;Kupffer cells: 1789.9;Langerhans cells: 6618.2;Macrophages: 3639.1;monocytes: 3188.2;Plasma cells: 1740.9;T-cells: 2235.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 5714.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 5714.1" "Cell line enhanced" "Detected in many" "HL-60: 4442.1;NB-4: 2549.7;THP-1: 4346.8;TIME: 2609.1;U-937: 3546.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000759 Enhanced Supported "Golgi apparatus" "Secreted to blood" NA NA 100000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" "HPA000759: AB_1079675" "unprognostic (3.61e-2)" "unprognostic (1.62e-2)" "unprognostic (2.78e-2)" "unprognostic (1.28e-1)" "unprognostic (1.37e-1)" "unprognostic (4.50e-2)" "unprognostic (1.30e-1)" "unprognostic (1.70e-2)" "unprognostic (1.63e-1)" "unprognostic (8.22e-2)" "unprognostic (5.80e-2)" "unprognostic (9.82e-2)" "prognostic unfavorable (3.18e-5)" "unprognostic (1.65e-1)" "unprognostic (2.32e-2)" "unprognostic (4.07e-2)" "unprognostic (4.08e-2)" 404.6 114.9 48.8 799.8 50.5 8096.7 136.4 55.5 99.6 93.2 70.1 101.8 77.9 63.5 25.9 91.0 96.8 316.4 111.9 48.2 67.8 98.3 239.4 347.3 437.2 82.4 59.3 30.7 68.4 131.6 62.1 355.6 67.8 58.9 118.9 15.5 40.1 57.4 37.5 18.9 111.4 219.4 65.5 362.8 95.0 18.3 64.7 228.9 72.7 117.1 314.6 508.3 46.1 71.0 5.3 43.0 0.2 0.4 768.1 749.7 1.2 94.9 63.9 235.1 283.5 0.1 18.2 9.1 117.4 4.1 134.4 1.1 0.0 20.6 799.9 535.7 0.4 87.1 29.8 0.3 312.7 4442.1 914.9 306.8 1.1 641.5 39.2 223.8 1227.8 13.3 82.5 419.9 1239.9 0.2 18.7 2549.7 0.7 0.1 84.6 2.4 2.3 446.7 0.6 6.0 0.3 0.8 2.3 0.6 16.0 0.0 2.2 4346.8 2609.1 187.9 12.9 3.8 20.1 486.4 508.4 57.3 112.2 3546.9 1.2 2349.8 1105.3 2730.6 474.9 774.6 313.4 73.5 228.5 362.8 583.0 39.0 125.5 268.4 5714.1 962.8 693.6 631.9 392.6 1590.5 48.8 50.5 55.5 99.6 48.2 67.8 82.4 59.3 67.8 65.5 64.7 71.0 1081.4 112.2 198.1 0.7 592.0 175.9 12.5 38.3 8.6 1.1 16.0 28.2 21.2 21.5 57.5 33.1 0.0 10.2 2922.2 2.9 0.0 4.2 4.1 4.6 15.0 566.8 1.8 277.8 0.2 9.8 10.2 87.9 70.3 6.6 2343.1 0.4 636.1 22.1 847.1 0.0 0.5 1.7 0.0 1789.9 6618.2 8.4 7.5 3639.1 556.7 80.6 3188.2 1.4 1292.5 0.0 0.2 1.3 1.2 18.0 1740.9 12.2 0.3 4.7 45.6 5.0 72.3 22.8 97.5 0.9 2.2 8.7 141.8 14.2 2235.9 1.2 5.5 18.1 ST6GALNAC3 SIAT7C ENSG00000184005 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3" Q8NDV1 1 76074746-76634603 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.0" "Group enriched" "Detected in many" 4 "Microglial cells: 912.5;Oligodendrocytes: 698.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 35.8;HUVEC TERT2: 45.9;SK-MEL-30: 62.3;TIME: 20.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054566, HPA055399" Uncertain Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA054566: AB_2682526, HPA055399: AB_2682806" "unprognostic (7.85e-2)" "unprognostic (1.78e-1)" "unprognostic (2.99e-2)" "unprognostic (2.70e-4)" "unprognostic (2.76e-2)" "unprognostic (2.21e-2)" "unprognostic (6.55e-3)" "unprognostic (7.31e-2)" "unprognostic (2.14e-1)" "unprognostic (4.57e-1)" "unprognostic (1.50e-1)" "unprognostic (5.95e-2)" "unprognostic (9.97e-4)" "unprognostic (3.33e-4)" "unprognostic (5.44e-2)" "unprognostic (1.92e-1)" "unprognostic (3.44e-4)" 8.8 1.4 5.8 1.8 13.3 3.1 6.4 14.3 8.4 1.9 10.4 2.0 0.7 5.9 0.5 1.9 2.7 2.5 4.4 6.9 9.0 8.7 2.0 5.2 2.0 15.2 10.6 2.3 0.9 4.4 2.1 3.1 17.2 1.1 2.4 3.9 1.1 1.6 1.6 0.8 1.4 4.5 13.3 1.4 1.5 0.3 11.3 0.9 13.3 6.5 0.7 2.6 1.6 21.0 0.2 0.0 35.8 0.0 0.6 0.0 0.0 0.0 4.2 0.6 0.4 11.9 0.1 0.6 2.4 0.3 2.3 0.1 0.0 0.4 0.3 0.0 2.5 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.6 0.0 0.0 1.1 45.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 2.9 0.0 1.8 1.7 0.0 0.0 0.0 2.7 8.8 0.0 0.0 62.3 8.3 0.0 0.2 20.6 0.3 2.8 0.1 3.3 0.0 0.0 0.0 0.0 8.4 5.5 0.0 6.3 2.8 0.0 2.2 0.0 2.6 0.3 0.5 2.3 3.8 1.3 1.4 3.9 0.3 4.3 0.0 0.0 1.9 5.8 13.3 14.3 8.4 6.9 9.0 15.2 10.6 17.2 13.3 11.3 21.0 59.8 3.2 1.5 174.3 5.6 0.3 0.2 0.0 0.6 3.2 0.6 1.0 1.2 0.0 0.0 3.7 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.1 4.5 23.2 0.0 0.4 107.0 0.0 0.1 2.5 3.6 0.1 0.0 0.8 66.0 0.8 1.1 0.0 101.4 0.5 0.0 9.8 0.7 0.8 0.0 3.7 5.4 912.5 3.0 12.3 1.0 23.1 698.3 0.2 3.4 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 1.1 1.3 0.2 0.7 0.1 0.4 0.1 2.0 6.9 0.3 0.1 ST7 "ETS7q, FAM4A, FAM4A1, HELG, RAY1, SEN4, TSG7" ENSG00000004866 "Suppression of tumorigenicity 7" Q9NRC1 7 116953238-117230176 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 184.1;Early spermatids: 131.4;Excitatory neurons: 191.5;Inhibitory neurons: 176.0;Oligodendrocyte precursor cells: 111.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-BR-3: 115.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038325, HPA038326" Approved Supported Nucleoplasm,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm Cytosol "HPA038325: AB_10671740, HPA038326: AB_10672644" "unprognostic (3.40e-2)" "unprognostic (1.04e-1)" "unprognostic (1.33e-1)" "unprognostic (4.70e-2)" "unprognostic (1.09e-1)" "unprognostic (8.18e-2)" "unprognostic (3.32e-2)" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (4.45e-3)" "unprognostic (1.46e-1)" "unprognostic (2.48e-2)" "prognostic favorable (3.39e-5)" "unprognostic (1.80e-1)" "unprognostic (1.96e-1)" "unprognostic (8.41e-2)" "unprognostic (3.40e-2)" 13.5 21.7 22.6 6.7 22.0 17.8 15.2 50.6 24.7 19.9 11.1 13.6 12.1 14.5 35.8 9.7 18.6 12.3 22.4 21.8 22.6 29.4 41.3 26.1 7.6 15.0 17.4 17.4 32.9 19.0 24.5 20.9 15.9 13.8 12.4 12.6 21.7 21.2 12.5 11.5 11.0 12.6 14.6 10.4 17.3 8.7 22.5 8.6 28.4 11.2 8.6 12.6 11.1 19.7 29.4 17.2 28.2 24.4 31.0 20.5 12.3 23.0 30.2 24.4 35.2 24.0 32.8 7.7 25.5 21.4 34.7 24.6 24.2 24.5 31.3 11.1 33.9 23.4 26.5 20.2 21.8 27.4 39.4 16.1 24.3 30.7 21.8 21.6 24.9 5.2 36.0 54.6 22.3 18.1 0.2 21.0 26.9 40.1 19.3 6.7 18.8 33.6 25.5 16.2 42.2 33.8 27.8 115.5 32.0 20.6 10.1 23.3 19.1 27.6 11.0 30.5 23.3 34.7 28.2 29.6 22.9 24.0 28.6 1.5 3.1 0.4 7.3 1.2 5.1 2.2 4.4 6.2 5.7 1.0 2.9 3.0 0.0 7.0 1.1 5.6 10.3 3.0 22.6 22.0 50.6 24.7 21.8 22.6 15.0 17.4 15.9 14.6 22.5 19.7 6.3 22.4 38.1 184.1 5.0 7.5 8.6 8.8 10.8 12.2 9.0 7.4 13.5 12.8 12.9 5.5 0.0 21.1 6.4 3.1 5.9 6.0 131.4 7.1 5.9 9.5 3.6 15.8 191.5 13.4 22.8 10.6 12.8 14.2 19.6 3.5 8.6 24.5 8.7 3.3 176.0 6.8 8.2 14.4 6.0 53.5 11.1 7.9 7.2 44.0 7.5 12.8 4.1 111.1 46.9 8.8 3.6 6.0 10.3 6.7 3.6 17.3 6.3 1.3 0.0 9.9 12.1 12.8 5.8 7.4 5.5 21.2 4.6 4.6 5.3 8.8 ST8SIA6 SIAT8F ENSG00000148488 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6" P61647 10 17315421-17454595 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.5;lung: 5.9" "Cell type enriched" "Detected in some" 5 "Microglial cells: 137.7" "Cancer enhanced" "Detected in some" "breast cancer: 5.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 8 "HMC-1: 208.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011635, HPA072708" Uncertain Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA011635: AB_2194921, HPA072708: " "unprognostic (4.86e-3)" "unprognostic (7.01e-2)" "unprognostic (5.85e-3)" "unprognostic (2.21e-2)" "unprognostic (3.43e-2)" "unprognostic (2.21e-2)" "unprognostic (1.11e-2)" "unprognostic (6.81e-2)" "unprognostic (2.32e-1)" "unprognostic (3.23e-2)" "unprognostic (7.53e-2)" "unprognostic (1.25e-1)" "unprognostic (2.48e-2)" "unprognostic (3.26e-4)" "unprognostic (2.43e-1)" "unprognostic (2.22e-1)" "unprognostic (1.07e-3)" 0.7 0.3 5.8 0.4 4.1 1.8 5.2 3.2 3.6 0.3 2.4 0.6 0.3 0.4 4.6 0.5 0.3 0.5 3.4 2.9 3.3 0.8 1.0 5.9 0.2 5.4 10.5 0.4 0.2 0.0 0.3 1.1 4.6 1.5 0.4 0.4 0.6 0.2 0.2 1.0 0.4 0.3 3.6 0.6 0.3 0.3 8.0 0.3 0.4 0.8 0.4 0.2 0.4 4.3 0.2 0.2 0.1 1.7 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.6 0.6 0.0 0.1 0.3 0.3 0.5 0.1 0.0 0.0 0.4 0.2 25.9 0.4 0.5 0.0 0.0 208.0 0.1 0.0 0.2 0.1 1.8 0.0 0.3 4.6 0.4 2.5 1.9 1.1 0.4 2.1 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 9.3 0.2 1.1 0.0 3.6 0.1 0.3 0.0 0.1 0.1 0.2 0.1 0.1 0.4 0.1 1.7 0.5 0.5 0.5 0.1 0.2 0.1 0.3 0.3 0.2 0.3 0.3 0.4 1.0 0.7 0.3 0.2 0.8 0.2 5.8 4.1 3.2 3.6 2.9 3.3 5.4 10.5 4.6 3.6 8.0 4.3 0.6 0.0 0.0 2.6 0.1 0.6 0.1 0.2 0.0 0.0 10.0 3.9 0.8 0.0 0.2 0.0 0.0 0.0 5.5 1.2 0.0 0.0 0.5 0.1 0.0 10.9 0.0 25.5 3.0 0.0 0.0 0.3 0.0 0.8 10.2 2.8 26.7 0.0 0.1 0.0 4.4 0.0 0.0 0.9 0.0 0.6 0.0 0.2 8.8 137.7 0.2 0.0 8.2 1.5 1.1 0.1 0.1 0.0 1.8 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.8 0.3 0.0 0.0 0.0 2.4 0.1 0.0 0.1 STAB2 "DKFZP434E0321, FEEL-2, FELL, HARE, SCARH1, STAB-2" ENSG00000136011 "Stabilin 2" Q8WWQ8 12 103587273-103766719 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 65.9" "Cell type enriched" "Detected in some" 11 "Hepatic stellate cells: 145.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BEWO: 11.5;HaCaT: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA026871, HPA072699" Enhanced Supported Cytosol NA NA 1200000 "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA026871: AB_1857536, HPA072699: " "unprognostic (5.66e-3)" "unprognostic (7.51e-2)" "unprognostic (3.31e-1)" "unprognostic (3.84e-2)" "unprognostic (8.47e-2)" "unprognostic (2.15e-2)" "unprognostic (1.23e-1)" "unprognostic (2.81e-1)" "unprognostic (5.72e-2)" "unprognostic (1.92e-1)" "unprognostic (4.24e-2)" "unprognostic (1.05e-1)" "unprognostic (9.72e-4)" "unprognostic (1.37e-2)" "unprognostic (5.00e-1)" "unprognostic (1.26e-1)" "unprognostic (2.06e-1)" 0.9 0.2 0.8 0.9 0.5 0.7 0.9 0.1 0.6 1.0 0.0 2.8 0.3 0.9 1.5 0.8 1.3 1.0 0.4 1.3 0.1 0.4 14.7 0.5 3.9 0.4 0.0 0.5 0.3 0.0 0.3 0.3 0.3 0.3 0.4 0.3 0.4 0.0 0.2 0.3 0.6 0.2 0.1 65.9 0.4 2.2 0.3 0.0 1.1 0.0 0.4 0.7 0.5 0.1 0.2 0.5 0.5 0.1 0.0 0.0 11.5 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 3.2 0.0 0.0 0.0 0.0 0.8 0.3 0.7 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.4 0.1 1.8 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.6 0.2 0.0 0.4 0.6 0.3 0.0 0.8 0.1 0.1 0.0 0.2 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.5 0.1 0.6 1.3 0.1 0.4 0.0 0.3 0.1 0.3 0.1 0.2 0.0 0.0 0.7 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.8 4.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.1 0.0 0.0 4.0 0.0 0.0 2.7 0.0 0.6 0.2 0.0 0.0 0.0 0.0 145.6 4.1 0.1 0.0 1.9 0.0 0.0 11.6 0.7 12.2 0.3 0.0 0.0 1.0 0.0 0.0 0.0 2.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.0 STAC STAC1 ENSG00000144681 "SH3 and cysteine rich domain" Q99469 3 36380503-36548007 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 13.8" "Cell type enhanced" "Detected in some" "Distal tubular cells: 5.9;Early spermatids: 5.2;granulocytes: 6.3;Granulosa cells: 12.5;Late spermatids: 5.3;Muller glia cells: 21.6;Smooth muscle cells: 5.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 1.5;NK-cell: 1.3;T-reg: 1.5" "Group enriched" "Detected in many" 5 "granulocytes: 1.5;NK-cells: 1.3;T-cells: 1.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 46.8;HaCaT: 34.1;SH-SY5Y: 49.1;U-251 MG: 30.3;U-87 MG: 48.1" "Low region specificity" "Detected in many" HPA035143 Uncertain Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA035143: AB_10603892" "unprognostic (5.29e-2)" "unprognostic (7.61e-2)" "unprognostic (2.58e-1)" "unprognostic (1.44e-6)" "unprognostic (4.24e-2)" "unprognostic (1.83e-2)" "unprognostic (3.06e-2)" "unprognostic (3.89e-1)" "unprognostic (2.02e-1)" "unprognostic (3.31e-3)" "unprognostic (1.77e-3)" "unprognostic (5.82e-2)" "unprognostic (8.07e-2)" "unprognostic (1.73e-4)" "unprognostic (8.93e-2)" "unprognostic (1.95e-1)" "unprognostic (7.94e-3)" 2.8 5.1 1.4 0.6 1.9 0.4 1.9 3.6 3.9 7.0 5.0 3.6 0.1 1.4 0.3 2.1 3.2 2.7 0.7 0.8 4.3 2.5 0.9 11.1 0.4 2.3 2.5 2.5 0.1 10.1 1.1 0.3 6.9 13.8 0.7 5.8 1.3 4.4 1.6 1.2 0.4 3.4 1.9 0.6 0.9 1.9 2.1 0.7 0.5 5.3 0.2 3.7 2.2 0.5 7.7 3.3 1.6 0.0 6.5 2.1 0.1 19.9 0.4 4.0 4.6 0.0 0.0 0.0 7.8 46.8 13.0 34.1 2.4 8.2 4.1 0.0 7.2 1.1 10.0 0.2 0.0 20.3 0.4 2.4 0.2 0.1 0.7 27.6 0.0 1.8 0.0 0.4 0.5 0.0 4.1 0.2 13.8 0.0 3.0 0.0 0.0 0.0 10.8 0.0 6.2 49.1 7.9 5.2 0.1 13.6 0.0 2.0 8.5 0.5 19.1 0.6 30.3 0.0 0.0 0.0 48.1 7.9 8.3 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1.5 0.0 1.4 1.9 3.6 3.9 0.8 4.3 2.3 2.5 6.9 1.9 2.1 0.5 0.9 0.0 0.5 0.3 0.0 0.0 0.0 0.5 0.0 0.7 2.3 0.8 0.9 0.0 1.3 0.0 0.0 0.0 0.1 0.0 5.9 0.2 5.2 0.9 0.5 0.4 0.0 2.1 0.6 0.0 0.1 1.5 0.0 2.1 6.3 12.5 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 2.2 5.3 0.0 4.8 0.0 0.0 0.0 21.6 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.4 5.0 1.8 0.1 0.0 0.3 0.0 0.4 0.0 0.0 0.0 STARD3 "es64, MLN64" ENSG00000131748 "StAR related lipid transfer domain containing 3" Q14849 17 39637090-39664201 "Cancer-related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "SK-BR-3: 260.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017021, HPA024307, HPA073948" Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Vesicles" "Endoplasmic reticulum" "CAB017021: , HPA024307: , HPA073948: " "unprognostic (1.11e-1)" "unprognostic (2.14e-2)" "unprognostic (6.35e-2)" "unprognostic (8.92e-3)" "unprognostic (2.09e-2)" "unprognostic (2.94e-1)" "prognostic unfavorable (3.60e-5)" "unprognostic (2.26e-1)" "unprognostic (1.77e-1)" "unprognostic (1.48e-1)" "unprognostic (6.25e-3)" "unprognostic (5.88e-2)" "prognostic unfavorable (7.70e-4)" "unprognostic (1.33e-1)" "unprognostic (5.22e-2)" "unprognostic (8.51e-3)" "unprognostic (3.00e-2)" 24.8 33.4 18.3 18.8 29.1 25.4 23.4 21.6 18.9 22.3 14.9 21.5 24.1 20.4 2.7 24.1 21.5 17.2 16.3 17.9 15.4 18.9 25.8 28.8 22.3 21.1 21.3 21.3 26.5 15.2 24.0 17.1 19.0 20.1 5.2 3.2 21.2 11.3 23.9 27.0 26.7 9.2 18.7 33.1 26.5 26.2 22.5 14.8 21.4 9.5 8.8 21.0 20.1 18.5 29.3 47.6 18.6 33.5 19.9 22.9 31.2 23.1 24.9 27.1 24.3 24.0 47.6 25.2 47.7 17.8 30.8 55.4 11.3 21.0 6.3 36.2 34.5 15.2 18.8 30.1 25.9 29.6 35.5 24.5 19.0 29.8 12.6 19.0 23.4 36.4 41.0 27.4 23.5 24.7 32.2 25.6 22.2 15.3 20.6 28.5 31.4 40.1 15.0 35.7 24.9 29.1 16.1 260.8 64.0 10.8 34.1 41.7 26.3 43.2 29.5 46.5 43.6 27.5 37.8 18.7 36.2 36.8 45.1 23.7 36.3 54.4 42.7 35.5 30.7 20.8 29.6 32.7 38.3 26.1 29.1 27.8 63.6 39.6 29.3 18.7 38.5 33.8 18.3 29.1 21.6 18.9 17.9 15.4 21.1 21.3 19.0 18.7 22.5 18.5 45.8 3.2 7.5 31.0 23.2 16.6 13.0 23.4 14.2 12.6 19.9 14.6 3.4 18.6 14.8 11.0 37.5 28.5 32.9 21.0 9.8 26.5 2.7 9.7 11.7 35.8 27.5 11.1 17.3 35.4 37.2 16.2 29.6 11.0 19.0 22.2 45.0 11.9 49.8 18.5 14.8 11.6 14.2 49.0 18.5 5.3 17.1 27.7 5.4 9.4 18.5 15.8 29.9 12.1 30.2 35.9 22.9 13.2 24.3 20.2 41.5 10.3 8.3 13.2 13.1 21.8 14.4 9.3 16.2 15.9 16.9 40.0 35.2 18.6 15.1 20.1 STARD5 MGC10327 ENSG00000172345 "StAR related lipid transfer domain containing 5" Q9NSY2 15 81309053-81324183 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 28.0;Plasma cells: 31.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 5.8;RPMI-8226: 6.2;U-266/70: 7.1;U-937: 6.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA040662 Approved Approved Vesicles,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles Cytosol "HPA040662: AB_10959593" "unprognostic (5.35e-4)" "unprognostic (1.55e-1)" "unprognostic (2.58e-2)" "unprognostic (2.76e-1)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (2.22e-4)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.10e-2)" "unprognostic (2.08e-2)" "unprognostic (8.08e-2)" "unprognostic (6.81e-2)" "unprognostic (2.08e-2)" "unprognostic (1.46e-2)" "unprognostic (4.84e-3)" "unprognostic (7.55e-3)" 1.0 0.6 0.6 6.0 0.8 4.3 0.7 3.4 1.3 7.2 1.9 2.8 2.2 4.6 5.0 3.4 1.8 1.3 0.8 0.6 0.7 0.7 5.1 1.1 7.7 0.9 1.0 1.2 0.6 0.6 0.4 1.6 1.2 3.6 3.7 0.4 1.6 2.1 0.6 7.9 4.2 1.8 0.9 6.2 2.1 0.7 0.7 0.5 0.8 0.3 1.5 2.5 5.5 1.4 0.3 0.0 0.0 0.9 2.3 2.3 0.1 0.3 0.3 0.8 1.2 0.1 0.1 4.8 0.0 1.5 0.2 4.0 1.1 1.0 0.6 0.1 0.4 1.8 0.3 0.4 0.5 2.8 5.8 2.0 2.0 0.3 0.6 1.5 0.1 1.9 0.6 1.3 0.5 0.1 0.5 4.0 0.3 0.2 0.0 0.1 0.7 6.2 0.3 1.4 0.3 0.1 0.1 0.5 0.6 0.3 0.6 0.6 0.2 1.3 0.6 1.3 0.1 7.1 1.5 1.8 0.9 6.8 0.4 5.0 1.8 2.3 3.0 2.4 2.5 1.0 2.7 3.2 2.6 0.7 3.9 3.9 1.3 2.6 2.3 1.4 3.6 3.7 0.6 0.8 3.4 1.3 0.6 0.7 0.9 1.0 1.2 0.9 0.7 1.4 3.8 0.0 1.1 0.0 11.4 13.3 12.0 28.0 10.8 1.8 2.7 4.2 0.3 0.0 4.9 0.0 6.2 2.5 4.2 22.1 3.9 1.3 15.2 2.5 14.4 2.5 11.4 2.5 2.2 1.4 4.0 8.5 15.8 2.3 10.2 1.0 3.6 25.4 5.2 1.7 2.0 24.3 2.0 7.9 10.9 1.5 5.0 8.0 1.8 1.9 0.7 1.2 2.1 0.0 0.4 1.8 14.4 9.8 31.5 3.3 23.9 0.7 4.0 0.9 0.0 3.8 2.8 0.9 0.7 19.6 16.3 4.9 4.2 6.3 19.9 9.6 STEAP3 "dudlin-2, STMP3, TSAP6" ENSG00000115107 "STEAP3 metalloreductase" Q658P3 2 119223831-119265652 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, Cell cycle, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 189.5;parathyroid gland: 78.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 33.3;Exocrine glandular cells: 36.2;Hepatocytes: 91.6;Respiratory ciliated cells: 36.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.4;intermediate monocyte: 2.7;myeloid DC: 4.1;NK-cell: 1.3" "Group enriched" "Detected in many" 6 "dendritic cells: 4.1;monocytes: 2.7;NK-cells: 1.3" "Cell line enhanced" "Detected in many" "U-87 MG: 149.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA050510 Approved Approved Nucleoli,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 15: Hepatocytes - Hemostasis" Cytosol Nucleoli "HPA050510: AB_2681151" "unprognostic (6.51e-2)" "unprognostic (6.48e-2)" "unprognostic (4.89e-2)" "unprognostic (3.45e-2)" "unprognostic (1.94e-3)" "unprognostic (9.07e-2)" "unprognostic (1.99e-2)" "unprognostic (3.04e-1)" "unprognostic (9.75e-2)" "unprognostic (1.58e-3)" "unprognostic (5.08e-3)" "unprognostic (6.95e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.82e-1)" "unprognostic (4.45e-1)" "unprognostic (9.37e-2)" "unprognostic (6.82e-2)" 9.1 6.3 4.3 3.9 3.7 16.9 14.5 7.1 4.6 16.7 10.6 9.5 22.1 3.6 5.3 15.8 7.7 2.3 9.5 7.0 7.5 6.9 189.5 9.1 0.9 14.4 9.4 4.4 27.1 78.9 13.8 11.3 12.8 11.8 6.9 0.7 34.3 7.5 29.9 9.0 10.9 3.1 7.6 1.8 22.5 1.9 7.2 2.2 5.4 12.5 3.1 7.0 7.2 12.7 21.8 25.6 0.0 8.7 12.1 112.9 22.1 6.8 7.4 13.1 11.8 19.5 29.0 0.1 49.9 38.5 94.1 35.9 11.1 22.4 14.9 0.1 35.9 42.1 22.2 38.8 30.0 10.5 7.7 67.3 38.7 78.0 27.7 89.8 11.4 0.0 20.9 4.2 37.6 20.6 0.1 6.2 34.2 33.3 52.7 0.2 14.7 18.5 16.2 54.1 41.9 7.7 18.8 64.1 4.9 4.9 12.7 13.7 49.6 81.2 46.8 17.4 37.4 0.1 0.1 0.2 149.1 26.2 17.2 0.0 2.4 0.4 0.1 2.7 0.0 0.4 0.0 0.0 4.1 0.1 0.0 0.0 0.0 1.3 0.4 0.2 0.0 1.0 4.3 3.7 7.1 4.6 7.0 7.5 14.4 9.4 12.8 7.6 7.2 12.7 9.1 0.0 7.9 2.3 1.0 2.0 7.4 11.9 8.0 0.6 15.5 10.7 6.2 2.8 16.2 0.0 0.0 33.3 0.2 12.2 0.0 8.1 0.2 8.1 1.9 6.2 1.8 29.5 1.3 36.2 4.1 3.6 23.4 5.7 3.8 3.5 1.4 91.6 10.9 0.0 1.0 6.0 8.2 5.9 3.8 0.7 1.8 6.1 0.0 1.9 1.4 0.1 0.0 0.5 0.0 20.8 7.7 7.5 0.1 8.3 11.8 1.5 36.1 0.1 6.6 4.1 3.3 0.6 0.2 19.5 1.4 23.7 0.4 13.1 11.6 8.9 STK32A "MGC22688, YANK1" ENSG00000169302 "Serine/threonine kinase 32A" Q8WU08 5 147234963-147387855 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 11.2;brain: 24.4" "Cell type enriched" "Detected in many" 19 "Oligodendrocyte precursor cells: 306.6" "Group enriched" "Detected in many" 5 "glioma: 4.3;melanoma: 11.9;thyroid cancer: 9.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "RT4: 13.6;SK-MEL-30: 48.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040236 Approved Centrosome NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" Centrosome "HPA040236: AB_10795416" "unprognostic (1.90e-1)" "unprognostic (4.71e-4)" "unprognostic (5.32e-2)" "unprognostic (3.49e-2)" "unprognostic (7.62e-2)" "unprognostic (6.82e-2)" "unprognostic (2.66e-2)" "unprognostic (2.96e-3)" "unprognostic (4.85e-2)" "unprognostic (2.36e-2)" "unprognostic (3.87e-1)" "unprognostic (8.38e-2)" "unprognostic (2.50e-3)" "unprognostic (5.53e-5)" "unprognostic (2.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.67e-3)" 1.3 11.2 5.9 0.6 9.5 0.0 1.2 13.2 3.1 1.0 1.0 2.3 0.5 0.5 2.6 0.3 0.8 1.5 1.0 3.5 14.4 3.4 0.1 1.2 0.0 11.7 24.4 2.5 2.6 0.1 8.1 0.1 17.0 1.0 0.3 2.6 0.9 0.8 0.2 3.7 0.7 0.4 10.4 0.3 1.2 1.0 14.0 0.1 8.7 0.5 0.0 1.7 1.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.5 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.5 0.0 1.1 0.0 0.0 0.2 4.4 13.6 1.2 0.5 0.0 0.0 48.6 0.2 0.0 0.0 0.1 0.0 0.5 0.7 0.4 1.0 0.2 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 9.5 13.2 3.1 3.5 14.4 11.7 24.4 17.0 10.4 14.0 10.1 0.2 0.0 2.6 8.5 0.0 1.5 0.2 1.4 0.0 1.8 1.3 0.5 0.5 0.0 1.0 1.8 0.0 0.0 0.0 0.1 1.9 1.8 6.9 0.2 0.5 0.1 0.0 0.0 4.6 2.7 0.0 2.7 0.0 0.7 0.0 4.2 0.0 0.0 0.1 0.0 5.2 0.0 2.0 0.0 1.0 10.5 0.9 0.2 16.0 0.0 0.0 4.0 0.0 306.6 0.7 5.5 0.0 4.1 0.0 0.3 0.0 4.1 0.2 1.0 0.0 5.4 0.5 0.0 0.1 0.0 0.3 0.1 0.1 1.4 0.0 0.6 STON1 "SBLF, stoned-b1" ENSG00000243244 "Stonin 1" Q9Y6Q2 2 48529383-48598513 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.0;Muller glia cells: 33.4;Sertoli cells: 26.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 1.9;neutrophil: 1.0" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "ASC diff: 23.7;ASC TERT1: 28.6;HSkMC: 36.1;hTERT-RPE1: 17.0;SuSa: 19.6" "Low region specificity" "Detected in all" HPA005715 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "HPA005715: AB_1080113" "unprognostic (1.61e-1)" "unprognostic (4.44e-1)" "unprognostic (7.97e-2)" "unprognostic (1.02e-4)" "unprognostic (1.54e-1)" "unprognostic (2.11e-1)" "unprognostic (1.35e-1)" "unprognostic (3.01e-2)" "unprognostic (8.99e-3)" "unprognostic (1.09e-1)" "unprognostic (1.76e-1)" "unprognostic (2.10e-2)" "prognostic unfavorable (4.69e-4)" "unprognostic (1.06e-2)" "unprognostic (2.50e-1)" "unprognostic (8.68e-2)" "unprognostic (2.49e-3)" 20.8 5.2 2.3 5.7 2.8 0.5 10.9 10.5 2.0 10.5 10.7 34.5 3.6 27.4 4.6 16.0 17.2 15.6 6.4 1.9 7.1 9.3 2.1 10.9 2.8 33.2 12.5 24.5 1.9 2.1 2.8 18.4 25.9 21.7 8.4 18.1 2.5 19.3 2.2 4.1 7.9 25.1 25.6 7.4 13.0 1.1 4.1 2.5 4.6 6.3 1.4 22.2 10.5 29.2 0.1 0.0 8.6 0.1 23.7 28.6 4.9 1.0 9.2 0.9 2.1 0.1 0.0 0.0 0.3 12.0 4.6 9.0 8.3 0.3 1.7 0.1 2.3 1.4 0.6 0.0 13.5 0.0 0.4 36.1 1.7 2.5 1.0 17.0 16.4 0.8 0.2 0.2 5.7 0.5 0.7 0.3 8.0 0.0 0.1 1.3 1.7 0.0 0.9 6.6 0.3 1.9 0.7 1.5 4.0 19.6 0.7 0.3 8.8 3.0 2.3 0.0 0.7 0.5 0.1 0.0 1.6 0.1 1.9 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.3 2.8 10.5 2.0 1.9 7.1 33.2 12.5 25.9 25.6 4.1 29.2 16.4 0.0 0.5 0.0 1.1 2.4 15.4 1.1 16.5 3.8 0.8 1.8 2.3 0.0 0.8 5.5 2.1 15.1 0.5 0.6 3.9 0.8 0.4 1.9 42.0 7.7 2.4 0.0 0.0 0.4 1.0 9.9 0.5 2.6 0.0 3.9 11.4 0.2 2.7 13.5 0.0 0.3 0.0 1.3 2.8 0.9 12.2 1.6 0.0 0.0 1.2 33.4 1.0 0.0 0.0 0.4 0.3 10.1 0.2 13.8 0.4 2.0 0.6 2.3 26.3 1.9 15.1 0.3 1.7 1.9 2.4 12.6 1.5 2.6 0.9 14.3 STRADB "ALS2CR2, CALS-21, ILPIP, ILPIPA, PAPK" ENSG00000082146 "STE20 related adaptor beta" Q9C0K7 2 201387858-201480846 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 412.8;Proximal enterocytes: 124.0;Proximal tubular cells: 217.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "LHCN-M2: 188.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026549, HPA028520" Approved Uncertain Aggresome,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol Aggresome "HPA026549: AB_1844779, HPA028520: AB_10604100" "unprognostic (6.34e-2)" "unprognostic (2.48e-1)" "unprognostic (2.63e-1)" "unprognostic (3.56e-3)" "unprognostic (4.04e-2)" "unprognostic (7.64e-2)" "unprognostic (1.35e-1)" "unprognostic (1.58e-1)" "unprognostic (2.63e-3)" "unprognostic (2.65e-2)" "unprognostic (6.21e-2)" "unprognostic (2.74e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.08e-1)" "unprognostic (7.83e-2)" "prognostic favorable (4.45e-4)" "unprognostic (4.93e-2)" 29.9 53.2 24.1 8.9 26.3 80.9 16.8 26.2 30.8 10.6 22.4 27.6 37.0 13.2 17.4 17.0 10.4 14.3 38.0 25.3 26.2 73.3 104.9 10.6 14.5 27.7 25.9 14.1 17.6 6.2 17.4 19.7 27.3 11.1 30.3 40.5 13.9 7.7 109.0 8.4 42.9 10.2 26.7 13.7 9.1 15.8 25.6 11.4 17.9 69.5 11.6 9.7 9.3 30.2 12.6 21.5 36.2 47.0 58.5 73.8 25.6 25.6 43.4 34.9 51.6 29.6 11.9 0.1 16.0 40.7 42.4 12.6 35.8 23.9 62.7 14.9 30.1 15.2 9.6 62.9 43.9 18.4 16.7 62.5 21.6 43.7 39.0 63.5 26.5 28.5 33.4 5.3 188.5 6.8 17.2 31.1 49.2 11.7 22.6 22.8 14.5 9.6 29.2 9.9 6.0 29.3 17.6 13.1 76.8 66.0 6.7 34.4 25.7 20.6 16.1 26.6 19.3 21.1 39.0 5.8 35.8 8.2 20.5 5.5 12.9 16.3 9.2 14.4 8.3 28.8 12.2 13.4 17.2 35.8 15.5 15.6 2.6 29.0 13.1 7.7 16.4 15.8 24.1 26.3 26.2 30.8 25.3 26.2 27.7 25.9 27.3 26.7 25.6 30.2 5.0 9.6 4.2 17.0 20.2 2.2 6.8 6.5 11.4 13.8 24.9 10.8 27.8 28.6 6.1 14.7 83.4 51.0 6.3 40.9 39.2 12.4 3.9 7.5 7.4 5.6 16.9 412.8 20.8 15.4 27.6 13.6 6.6 10.2 5.7 12.0 7.9 94.6 19.2 11.8 19.8 22.6 8.2 16.9 5.2 8.1 10.8 13.5 16.0 15.0 14.8 19.6 7.2 26.7 26.0 9.0 35.2 3.8 10.9 10.2 124.0 217.8 5.3 19.1 6.6 21.7 6.6 45.0 46.7 15.2 1.4 27.9 8.9 26.8 25.0 9.1 STX11 ENSG00000135604 "Syntaxin 11" O75558 6 144150517-144191939 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Familial hemophagocytic lymphohistiocytosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 25.1;bone marrow: 56.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 85.0;granulocytes: 90.3;Langerhans cells: 271.6;Macrophages: 158.0;monocytes: 85.5;Suprabasal keratinocytes: 154.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 7 "basophil: 22.6;classical monocyte: 68.4;eosinophil: 43.5;intermediate monocyte: 81.1;myeloid DC: 25.4;neutrophil: 81.7;non-classical monocyte: 87.0" "Group enriched" "Detected in all" 8 "dendritic cells: 25.4;granulocytes: 81.7;monocytes: 87.0" "Cell line enhanced" "Detected in some" "HDLM-2: 17.2;Karpas-707: 10.1;RH-30: 6.9;TIME: 8.3;U-266/70: 11.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA007992 Approved NA NA 1100000 "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA007992: AB_1857620" "unprognostic (1.30e-3)" "unprognostic (1.19e-1)" "unprognostic (1.68e-1)" "unprognostic (2.62e-2)" "unprognostic (3.73e-2)" "unprognostic (8.96e-2)" "unprognostic (3.04e-2)" "unprognostic (1.74e-1)" "unprognostic (2.85e-1)" "unprognostic (1.03e-2)" "unprognostic (8.65e-2)" "unprognostic (1.36e-1)" "unprognostic (4.47e-3)" "unprognostic (7.07e-2)" "unprognostic (3.91e-2)" "unprognostic (8.50e-3)" "unprognostic (1.07e-1)" 25.1 4.4 0.6 5.8 0.6 56.5 14.5 0.6 1.1 1.9 0.7 2.8 1.0 1.4 0.3 5.1 2.6 2.1 7.3 0.7 0.8 3.6 3.1 21.3 5.5 1.0 0.7 0.9 1.1 0.6 2.1 2.4 0.9 1.3 0.9 0.2 2.1 0.3 2.5 8.2 3.3 1.9 0.8 14.1 2.0 1.1 0.9 1.8 7.5 0.9 3.5 4.0 3.2 1.1 0.4 0.1 0.1 3.9 0.2 0.3 0.6 0.4 0.3 0.4 0.7 0.1 0.4 0.1 0.4 0.6 0.7 0.6 0.0 0.1 0.2 17.2 0.6 3.0 0.6 0.1 1.0 0.9 0.5 0.0 0.0 0.2 0.1 0.2 4.3 0.8 0.1 10.1 0.5 0.2 0.4 0.9 0.0 0.0 0.3 0.1 6.9 0.6 0.0 1.9 0.2 0.1 1.2 0.1 1.7 0.3 0.1 3.8 8.3 0.2 1.0 0.4 0.3 11.6 4.6 0.1 0.2 2.1 0.4 22.6 68.4 43.5 6.0 81.1 3.8 1.4 2.7 5.1 25.4 2.4 1.0 3.0 81.7 3.2 87.0 2.7 8.3 43.9 0.6 0.6 0.6 1.1 0.7 0.8 1.0 0.7 0.9 0.8 0.9 1.1 41.9 54.5 10.7 0.0 16.6 85.0 11.3 6.3 3.4 0.0 11.1 4.6 4.5 4.3 6.6 1.8 0.0 0.9 38.1 0.1 0.0 6.4 0.4 3.7 0.7 23.7 3.5 6.1 0.1 2.6 5.7 11.2 0.5 5.0 90.3 0.2 8.2 1.4 30.1 0.0 0.1 0.4 2.0 73.7 271.6 1.2 0.6 158.0 44.4 2.8 85.5 0.0 21.6 0.0 0.1 6.1 3.3 0.0 63.1 14.4 0.0 0.1 10.7 0.1 0.0 46.6 9.7 3.0 3.8 11.2 154.6 28.0 36.6 3.2 0.6 33.3 SUMF2 DKFZp566I1024 ENSG00000129103 "Sulfatase modifying factor 2" Q8NBJ7 7 56064002-56080670 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA024040, CAB025743, HPA074892" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" Yes No 750000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "CAB025743: , HPA024040: AB_1857651, HPA074892: " "unprognostic (2.93e-1)" "prognostic unfavorable (6.58e-6)" "unprognostic (2.42e-2)" "prognostic favorable (3.96e-4)" "unprognostic (3.87e-2)" "unprognostic (9.11e-3)" "unprognostic (1.69e-2)" "unprognostic (1.19e-1)" "unprognostic (1.41e-1)" "unprognostic (7.20e-2)" "unprognostic (1.92e-1)" "unprognostic (7.26e-2)" "unprognostic (1.74e-1)" "unprognostic (1.74e-2)" "unprognostic (2.64e-1)" "unprognostic (1.99e-3)" "prognostic unfavorable (7.71e-4)" 64.1 64.6 26.1 43.0 29.7 51.5 57.5 29.3 27.1 91.3 45.0 67.4 89.2 57.5 64.8 46.8 102.6 70.6 30.8 25.1 27.8 93.4 94.8 71.6 50.2 35.2 29.6 59.7 91.8 115.8 31.8 45.5 33.4 79.3 69.1 11.0 69.5 77.1 22.4 47.5 74.4 57.7 29.9 57.0 92.7 23.7 30.8 57.6 91.2 21.4 51.3 57.2 43.6 35.9 352.3 102.9 46.0 211.8 214.4 147.5 68.9 114.5 156.1 92.6 114.5 57.2 278.0 57.1 96.5 162.4 90.4 172.3 27.4 131.3 61.1 90.6 42.9 36.4 63.5 54.2 138.4 89.7 108.7 116.8 124.5 83.7 143.3 186.9 137.7 101.4 116.4 236.6 151.3 76.8 77.2 115.7 63.5 272.0 52.2 61.5 45.4 359.0 127.7 39.1 54.0 65.6 142.4 294.2 140.9 98.9 294.5 144.5 115.2 85.6 121.1 211.1 98.6 160.8 130.8 84.0 139.7 165.7 283.2 58.1 60.3 22.0 71.1 80.5 90.9 59.8 70.9 71.8 72.3 49.1 75.3 75.2 4.4 49.0 90.3 132.6 82.7 90.2 26.1 29.7 29.3 27.1 25.1 27.8 35.2 29.6 33.4 29.9 30.8 35.9 44.0 57.7 30.5 20.5 47.3 33.8 44.1 46.1 39.9 25.7 57.9 25.4 10.4 87.2 31.0 90.1 14.6 44.5 85.3 45.1 19.6 95.3 3.8 93.1 70.2 43.7 59.3 41.7 21.2 55.7 96.7 54.7 55.5 78.9 54.5 47.0 51.0 91.3 68.1 43.7 24.4 61.8 22.4 79.8 38.7 8.0 69.6 50.4 53.4 14.0 73.0 23.8 70.0 10.6 24.2 48.4 64.6 47.4 65.0 50.7 91.8 45.6 34.5 13.5 52.6 41.6 44.1 31.6 28.6 52.8 41.9 46.7 52.7 58.7 85.8 42.7 SUMO1 "GMP1, OFC10, PIC1, SMT3C, SMT3H3, SUMO-1, UBL1" ENSG00000116030 "Small ubiquitin like modifier 1" P63165 2 202206182-202238599 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "cerebellum: 7.6" "CAB004269, HPA056956" Supported Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Nuclear bodies" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear membrane" "Nucleoli, Nuclear bodies" "CAB004269: AB_628300, HPA056956: AB_2683285" "unprognostic (7.15e-2)" "unprognostic (2.34e-2)" "unprognostic (1.49e-1)" "unprognostic (2.52e-3)" "unprognostic (2.89e-1)" "unprognostic (9.56e-3)" "unprognostic (1.76e-2)" "unprognostic (8.08e-2)" "unprognostic (1.78e-3)" "prognostic favorable (7.93e-4)" "unprognostic (7.06e-3)" "unprognostic (1.16e-1)" "unprognostic (4.64e-3)" "unprognostic (1.31e-2)" "unprognostic (7.58e-2)" "unprognostic (2.82e-2)" "unprognostic (2.19e-1)" 77.5 99.1 79.4 62.7 84.9 133.7 83.6 89.0 99.9 68.9 84.4 82.7 72.0 65.1 86.3 71.6 65.7 71.7 79.8 85.6 85.3 118.1 174.1 66.5 86.4 79.9 80.1 54.5 55.8 91.6 56.7 75.6 81.1 75.3 82.8 80.2 66.8 61.9 107.5 57.1 80.5 71.5 78.9 68.1 73.8 54.7 81.4 112.1 102.3 103.3 95.4 77.9 54.9 86.6 164.1 82.4 291.4 155.8 159.3 168.5 129.7 171.0 214.6 209.0 274.6 178.1 203.7 111.6 153.5 199.0 193.5 117.1 242.2 237.9 325.0 104.8 185.7 207.6 159.0 211.2 114.9 237.2 188.5 130.9 225.2 164.0 123.9 195.1 197.3 219.0 194.2 176.0 226.4 141.1 298.3 391.6 351.7 168.5 172.2 190.9 163.2 197.9 255.5 134.3 201.7 219.3 140.3 133.6 236.4 313.9 120.0 223.2 139.9 152.5 153.0 141.4 152.8 151.7 322.9 285.8 170.2 165.4 137.2 242.2 220.0 284.2 169.2 226.5 179.6 276.3 206.8 200.0 223.6 231.6 193.8 202.3 256.5 246.5 239.7 187.8 329.0 394.7 79.4 84.9 89.0 99.9 85.6 85.3 79.9 80.1 81.1 78.9 81.4 86.6 182.7 112.2 61.1 10.7 143.1 422.1 204.4 448.6 177.6 99.6 196.8 170.2 58.1 130.1 215.3 189.4 64.6 259.4 162.3 136.6 481.3 250.4 91.3 148.3 115.1 170.7 142.4 140.1 31.4 173.3 297.8 161.8 89.7 115.2 92.6 114.7 142.8 202.1 205.3 87.5 27.8 156.4 319.4 140.7 330.2 28.0 129.8 137.7 211.7 15.9 241.3 182.3 176.1 16.6 21.2 208.1 191.1 127.9 130.5 258.5 272.2 534.4 185.5 87.8 111.7 92.5 221.9 212.0 141.5 183.9 424.5 209.7 174.5 134.9 157.5 254.1 SUSD2 "BK65A6.2, FLJ22778, W5C5" ENSG00000099994 "Sushi domain containing 2" Q9UGT4 22 24181487-24189106 "Predicted membrane proteins" Receptor "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 99.8" "Group enriched" "Detected in many" 6 "Alveolar cells type 1: 250.0;Alveolar cells type 2: 151.5;Proximal enterocytes: 154.9" "Cancer enhanced" "Detected in all" "testis cancer: 64.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 29 "SK-BR-3: 898.7" "Low region specificity" "Detected in all" HPA004117 Enhanced Approved "Plasma membrane" NA NA 6800000 "Cluster 19: Lung - Lung function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "HPA004117: AB_1857674" "unprognostic (5.24e-3)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "unprognostic (7.30e-2)" "unprognostic (1.27e-2)" "unprognostic (5.40e-2)" "unprognostic (5.20e-2)" "unprognostic (1.89e-2)" "unprognostic (5.87e-2)" "unprognostic (1.20e-2)" "unprognostic (9.74e-3)" "unprognostic (8.97e-2)" "prognostic unfavorable (3.29e-5)" "unprognostic (2.72e-2)" "unprognostic (2.82e-2)" "unprognostic (1.88e-2)" "unprognostic (3.33e-3)" 12.1 9.6 4.9 1.9 2.8 0.2 9.5 1.7 5.8 13.6 2.2 4.8 12.8 9.8 0.5 2.8 15.0 1.8 12.5 1.6 5.3 32.6 2.9 99.8 2.2 22.9 6.9 5.4 4.3 1.5 7.1 3.6 26.5 5.6 1.0 0.1 4.7 5.6 2.2 28.2 34.6 3.4 6.8 3.6 6.3 3.2 13.2 0.8 17.8 1.4 1.3 5.4 11.0 10.0 5.1 10.4 0.1 0.0 18.8 24.3 0.8 2.4 0.1 0.1 0.0 7.8 0.6 1.4 21.5 0.5 0.4 1.4 0.1 0.5 0.0 0.6 0.3 0.0 0.4 30.6 8.0 0.0 0.3 21.5 0.4 0.1 6.2 0.0 0.1 0.0 0.5 0.3 0.0 9.1 0.3 0.4 0.7 2.5 0.3 0.3 0.0 2.5 0.1 0.2 1.7 13.5 0.7 898.7 0.2 3.6 3.0 0.0 0.0 0.1 0.9 0.7 0.1 1.1 1.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 2.8 1.7 5.8 1.6 5.3 22.9 6.9 26.5 6.8 13.2 10.0 1.7 250.0 151.5 0.3 0.6 0.3 0.3 2.6 0.0 0.0 3.4 3.4 6.8 0.0 20.9 1.8 0.0 13.8 0.3 0.7 5.9 0.1 0.0 1.3 0.7 1.1 1.8 0.0 0.2 0.0 0.7 6.7 0.5 1.3 3.8 0.1 2.9 0.5 1.1 0.0 0.1 5.5 2.0 0.0 0.3 0.4 0.6 0.8 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.4 154.9 27.8 3.6 0.0 0.0 0.6 22.1 1.7 1.3 0.7 2.7 26.4 1.1 0.0 1.6 0.6 SYDE1 "7h3, FLJ13511, SYD1" ENSG00000105137 "Synapse defective Rho GTPase homolog 1" Q6ZW31 19 15107401-15114985 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 140.3;Peritubular cells: 42.2;Sertoli cells: 85.5;Syncytiotrophoblasts: 134.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-138 MG: 107.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013328 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Golgi apparatus, Cytosol" "HPA013328: AB_1848705" "unprognostic (9.99e-2)" "unprognostic (3.73e-2)" "unprognostic (8.17e-3)" "unprognostic (1.65e-2)" "unprognostic (6.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.07e-2)" "unprognostic (2.46e-2)" "unprognostic (2.96e-1)" "unprognostic (5.01e-3)" "unprognostic (1.43e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (5.63e-7)" "unprognostic (1.82e-2)" "unprognostic (7.57e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (8.27e-4)" 23.3 12.6 7.8 5.7 8.0 0.0 17.6 7.4 7.8 27.6 15.7 28.6 3.8 32.9 4.6 6.6 23.2 5.7 20.8 6.9 7.2 16.3 4.9 18.1 3.5 9.7 8.0 23.5 6.0 2.5 6.7 15.4 7.9 18.2 2.5 1.4 6.1 11.5 5.4 8.6 11.7 10.8 7.8 12.9 13.5 4.7 8.5 0.9 12.4 3.8 1.4 23.9 18.8 7.3 11.2 17.4 9.0 23.9 19.9 18.2 7.1 46.9 33.7 44.4 37.5 4.1 7.0 0.0 30.3 46.5 15.2 7.0 7.0 8.1 24.6 0.3 8.0 1.6 34.2 7.6 37.7 0.1 0.1 32.1 5.9 26.6 12.0 26.8 8.2 0.0 0.0 0.1 33.6 5.9 0.0 0.0 14.7 0.3 17.3 0.0 22.4 0.2 11.1 1.8 0.3 17.8 25.9 15.9 31.6 8.7 1.9 1.2 17.5 107.3 32.8 49.6 50.4 0.1 0.3 0.2 29.3 0.1 46.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 8.0 7.4 7.8 6.9 7.2 9.7 8.0 7.9 7.8 8.5 7.3 18.6 3.2 1.1 3.6 0.2 2.4 0.8 1.2 1.8 0.3 0.9 3.2 4.1 1.5 0.8 1.8 0.0 7.6 0.0 0.0 0.0 4.7 10.0 0.7 13.6 15.2 0.0 0.0 0.0 0.4 140.3 16.2 0.0 0.5 0.0 12.8 20.0 0.3 3.4 1.7 0.0 0.0 0.0 1.0 2.7 19.3 29.5 0.6 14.2 6.5 0.0 20.0 0.0 1.0 0.2 1.7 0.0 42.2 0.0 0.5 0.0 6.1 0.1 0.8 85.5 10.7 30.8 3.1 0.6 0.3 2.6 134.5 0.4 7.5 0.0 0.2 SYNE3 "C14orf139, C14orf49, FLJ25605, LINC00341, NCRNA00341, Nesp3, Nesprin-3, NET53" ENSG00000176438 "Spectrin repeat containing nuclear envelope family member 3" Q6ZMZ3 14 95407266-95475836 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 19.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 70.2;Cone photoreceptor cells: 62.6;Rod photoreceptor cells: 103.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 46.5;ASC TERT1: 36.2;Karpas-707: 42.3;REH: 34.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA055227, HPA077140" Approved Supported "Nuclear membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" "Nuclear membrane" "HPA055227: AB_2682747, HPA077140: AB_2686826" "unprognostic (4.63e-2)" "unprognostic (6.99e-3)" "unprognostic (3.79e-1)" "unprognostic (1.48e-3)" "unprognostic (7.15e-2)" "unprognostic (2.12e-3)" "unprognostic (2.45e-1)" "unprognostic (2.61e-2)" "unprognostic (4.92e-1)" "unprognostic (2.87e-1)" "unprognostic (8.50e-2)" "unprognostic (3.32e-1)" "unprognostic (7.41e-6)" "unprognostic (1.31e-1)" "unprognostic (1.42e-1)" "unprognostic (6.95e-2)" "unprognostic (7.19e-2)" 19.1 3.4 5.1 4.3 9.5 13.7 12.6 5.8 6.7 4.0 8.7 2.8 1.5 2.3 1.4 2.0 4.5 2.1 4.3 4.5 5.5 1.1 3.0 4.4 6.0 10.0 8.0 4.0 0.9 0.4 1.7 3.4 7.4 1.6 2.6 11.9 3.2 1.1 2.2 4.3 3.8 2.2 5.6 5.0 2.1 2.7 8.3 2.4 2.9 3.3 6.0 3.2 4.1 12.3 1.2 0.1 0.7 1.1 46.5 36.2 14.3 5.4 9.4 5.1 4.0 7.8 1.3 6.3 0.9 2.6 1.6 0.3 1.1 4.0 2.3 20.9 0.9 4.3 0.9 2.1 6.0 6.6 10.4 10.2 1.4 6.4 3.7 0.4 9.0 1.9 0.3 42.3 3.9 1.5 3.9 7.3 0.1 0.2 2.6 34.8 23.2 13.5 0.6 0.7 1.0 5.1 0.2 0.1 2.5 0.6 2.0 9.6 8.2 3.7 2.2 5.0 0.7 5.0 11.1 5.9 7.4 14.6 28.2 2.2 1.9 0.1 0.7 1.5 0.9 1.2 1.0 0.8 0.8 1.0 1.2 1.0 0.9 0.3 1.6 1.0 0.9 1.0 5.1 9.5 5.8 6.7 4.5 5.5 10.0 8.0 7.4 5.6 8.3 12.3 12.4 9.6 18.3 3.3 19.7 2.3 0.4 0.1 0.6 5.1 1.0 1.3 70.2 0.0 0.7 0.0 62.6 2.2 16.1 4.9 0.0 0.0 3.9 6.5 5.1 14.7 1.2 4.0 2.5 0.4 15.0 22.3 1.1 1.4 12.0 0.2 5.0 6.8 4.3 6.7 3.3 5.0 0.0 17.6 14.8 2.4 13.1 20.3 5.4 3.7 27.8 5.3 9.2 14.1 20.8 0.5 6.2 0.4 20.6 1.9 2.9 0.4 6.6 103.7 6.6 19.1 12.1 0.6 1.1 0.3 1.0 1.9 14.0 0.0 1.9 0.5 SYNE4 "C19orf46, DFNB76, FLJ36445, Nesp4, Nesprin-4" ENSG00000181392 "Spectrin repeat containing nuclear envelope family member 4" Q8N205 19 36003307-36008813 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 32.0;Breast myoepithelial cells: 35.9;Cytotrophoblasts: 32.6;Syncytiotrophoblasts: 33.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "CACO-2: 32.5;Hep G2: 29.1;MCF7: 34.2;SK-BR-3: 40.1;T-47d: 31.0" "Region enriched" "Detected in single" 15 "cerebellum: 6.8" "Not detected" "Not detected" HPA060253 Uncertain NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "HPA060253: AB_2684233" "unprognostic (8.54e-2)" "unprognostic (6.48e-2)" "unprognostic (1.32e-2)" "unprognostic (1.24e-1)" "unprognostic (5.54e-2)" "unprognostic (2.42e-3)" "unprognostic (3.76e-2)" "unprognostic (2.03e-2)" "unprognostic (1.93e-1)" "unprognostic (3.15e-2)" "unprognostic (3.36e-3)" "unprognostic (6.02e-2)" "prognostic favorable (8.64e-9)" "unprognostic (1.25e-1)" "unprognostic (2.54e-2)" "unprognostic (4.50e-1)" "unprognostic (1.97e-2)" 0.2 0.2 1.2 0.2 1.0 0.2 5.2 6.7 1.5 2.6 2.5 1.9 3.2 0.7 7.7 1.2 3.9 1.6 0.2 0.7 2.9 8.4 12.0 3.1 0.2 3.7 3.0 0.3 5.4 12.1 12.7 1.6 3.6 10.9 1.4 0.2 9.2 4.0 0.3 1.1 1.3 0.2 1.3 0.3 3.4 0.2 2.5 1.7 8.6 0.0 0.3 0.8 1.3 1.2 0.3 0.3 0.2 0.4 0.1 0.2 4.3 0.0 0.0 0.0 0.1 32.5 3.8 0.3 0.4 0.0 0.2 0.0 0.3 0.4 0.0 1.1 0.5 0.1 0.8 29.1 0.5 0.0 0.2 0.2 0.2 1.1 0.0 0.0 0.2 1.6 0.4 0.4 0.0 34.2 0.5 0.1 0.2 0.3 0.2 0.9 0.0 0.4 2.2 1.0 5.0 0.0 0.0 40.1 0.2 0.2 31.0 0.3 0.0 0.3 0.6 0.5 0.2 0.5 0.7 0.6 0.3 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.0 6.7 1.5 0.7 2.9 3.7 3.0 3.6 1.3 2.5 1.2 0.3 6.4 17.5 0.3 0.7 0.5 14.9 19.9 5.2 0.9 32.0 35.9 0.4 24.3 20.2 29.5 4.2 32.6 0.8 5.4 25.4 21.2 0.0 9.1 1.0 0.8 29.8 0.0 0.6 8.6 24.7 0.7 8.2 10.7 1.3 0.5 0.7 12.5 2.6 0.0 0.9 10.6 26.4 0.6 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.9 11.7 16.9 0.0 0.0 23.9 4.5 24.2 17.3 0.4 0.0 0.3 1.6 0.1 0.4 2.1 0.4 33.9 1.2 0.1 8.8 9.2 SYNJ2BP Arip2 ENSG00000213463 "Synaptojanin 2 binding protein" P57105 14 70366499-70417090 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 140.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA000866 Approved Supported Approved Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 8: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA000866: AB_2276678" "unprognostic (2.68e-1)" "unprognostic (1.76e-1)" "unprognostic (2.67e-1)" "unprognostic (3.31e-1)" "unprognostic (1.28e-1)" "unprognostic (1.04e-1)" "unprognostic (1.65e-1)" "unprognostic (1.60e-2)" "unprognostic (5.70e-2)" "unprognostic (6.14e-2)" "unprognostic (6.35e-3)" "unprognostic (1.44e-2)" "prognostic favorable (1.11e-16)" "unprognostic (2.81e-1)" "unprognostic (1.38e-1)" "unprognostic (5.35e-3)" "unprognostic (1.14e-2)" 10.2 10.1 10.3 7.3 10.1 1.3 9.9 9.3 10.0 8.1 13.3 13.7 19.6 9.0 7.9 8.2 7.2 8.4 14.9 8.4 9.3 21.7 20.3 9.5 6.6 10.0 9.8 7.2 7.4 24.9 6.6 9.3 9.8 12.9 15.1 16.4 9.5 11.9 28.7 5.7 16.0 10.7 10.8 9.1 15.5 3.9 10.6 5.1 11.2 29.3 6.4 8.6 6.1 9.7 14.0 9.1 15.3 10.3 11.7 13.4 10.6 10.8 11.1 7.4 8.3 8.7 12.8 0.0 10.0 12.7 7.5 11.6 15.7 11.6 17.5 1.9 8.0 5.2 13.9 11.4 10.3 0.0 1.7 10.5 9.2 9.4 5.3 13.1 16.6 5.8 3.1 2.7 13.4 10.2 7.2 2.1 11.1 13.9 10.9 9.0 22.4 3.9 16.0 20.7 11.1 19.4 14.6 12.0 8.8 9.9 22.7 3.6 18.5 17.7 12.1 6.9 8.7 3.7 15.0 0.0 15.6 1.8 14.9 0.3 3.0 0.1 2.3 3.1 2.7 2.5 2.8 2.7 3.0 2.0 3.8 3.1 0.3 2.3 2.1 1.9 2.3 1.1 10.3 10.1 9.3 10.0 8.4 9.3 10.0 9.8 9.8 10.8 10.6 9.7 36.6 38.5 46.6 0.0 17.8 6.0 28.7 49.4 9.1 44.9 25.9 15.4 89.4 48.6 43.3 75.4 81.3 38.3 13.1 50.1 140.8 49.0 36.9 56.0 26.5 38.4 19.8 5.7 0.0 39.2 31.5 21.7 21.9 85.7 9.5 33.5 37.1 50.4 24.7 30.3 0.0 41.2 44.7 23.6 9.1 9.8 30.4 16.9 14.2 0.0 28.8 37.1 28.8 0.0 0.0 35.7 43.5 41.3 4.2 25.8 87.3 77.0 31.5 88.0 26.3 37.6 27.8 68.9 12.9 12.5 4.8 10.9 17.4 25.0 62.6 30.3 SYT8 DKFZp434K0322 ENSG00000149043 "Synaptotagmin 8" Q8NBV8 11 1828307-1837521 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 29.2;skin 1: 65.5;urinary bladder: 40.5" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 184.7;Basal squamous epithelial cells: 520.2;Breast myoepithelial cells: 192.9;Cholangiocytes: 183.0;Extravillous trophoblasts: 201.8;Respiratory ciliated cells: 163.8;Squamous epithelial cells: 132.5" "Group enriched" "Detected in many" 5 "cervical cancer: 10.5;pancreatic cancer: 21.7;urothelial cancer: 33.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CAPAN-2: 32.2;hTCEpi: 50.2;T-47d: 13.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047239, HPA052700" Uncertain Approved "Nucleoli fibrillar center,Endoplasmic reticulum" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoli fibrillar center, Endoplasmic reticulum" "HPA047239: , HPA052700: AB_2681920" "unprognostic (1.66e-3)" "unprognostic (2.42e-1)" "unprognostic (1.12e-2)" "unprognostic (2.14e-1)" "unprognostic (6.31e-2)" "unprognostic (2.06e-1)" "unprognostic (3.10e-2)" "unprognostic (1.36e-2)" "unprognostic (1.02e-1)" "unprognostic (8.25e-2)" "unprognostic (7.09e-2)" "unprognostic (2.48e-1)" "unprognostic (2.33e-6)" "unprognostic (2.87e-2)" "unprognostic (1.75e-1)" "unprognostic (5.52e-2)" "unprognostic (2.77e-2)" 0.1 0.2 0.0 0.0 0.0 0.0 5.1 0.0 0.0 1.3 0.1 0.4 0.5 0.0 0.5 29.2 1.0 8.6 0.0 0.0 0.0 0.3 0.6 4.7 0.0 0.0 0.0 0.0 14.9 0.0 0.2 1.6 0.0 2.5 0.0 0.0 20.9 2.9 0.0 65.5 2.5 0.0 0.0 0.1 2.3 0.2 0.0 0.0 0.0 0.0 0.1 40.5 3.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 32.2 0.0 0.0 0.0 0.6 0.6 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 50.2 0.0 5.8 0.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 5.7 0.0 0.0 0.3 0.0 0.1 1.0 0.0 0.3 0.0 2.7 0.0 0.0 13.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 16.0 3.9 0.0 0.3 184.7 5.6 24.9 520.2 0.0 3.2 192.9 0.6 183.0 39.1 5.5 0.0 28.7 0.7 3.4 0.0 31.1 0.0 15.6 0.1 1.7 0.0 0.0 0.0 9.7 201.8 1.6 12.2 0.6 1.3 0.0 0.0 0.1 7.1 0.0 0.0 1.3 16.2 0.0 14.7 0.0 0.0 1.3 10.6 0.0 0.0 0.0 0.0 0.0 0.0 28.3 3.5 0.0 6.2 1.3 18.3 0.0 163.8 0.0 0.0 0.0 7.0 0.0 0.0 132.5 47.2 36.8 0.6 0.1 1.7 31.5 SYTL1 "exophilin-7, FLJ14996, JFC1, SLP1" ENSG00000142765 "Synaptotagmin like 1" Q8IYJ3 1 27342020-27353937 "Plasma proteins, Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 103.9;pancreas: 106.3;skin 1: 87.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 158.8;NK-cells: 208.1;Squamous epithelial cells: 179.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 4.3;cerebellum: 8.8" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 47.8;CAPAN-2: 55.8;NB-4: 81.8;U-266/70: 44.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA037825 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 24: NB-4 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA037825: AB_10671635" "unprognostic (4.23e-2)" "unprognostic (8.23e-2)" "unprognostic (2.40e-1)" "prognostic favorable (6.83e-7)" "unprognostic (7.81e-3)" "unprognostic (5.81e-2)" "unprognostic (1.05e-1)" "unprognostic (7.18e-3)" "unprognostic (4.41e-1)" "unprognostic (1.14e-2)" "unprognostic (2.07e-1)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (1.45e-1)" "unprognostic (3.02e-1)" "unprognostic (1.72e-2)" "unprognostic (5.88e-3)" 2.0 0.6 4.3 19.1 0.7 46.7 7.7 8.8 1.4 22.6 6.1 6.7 7.8 1.3 1.2 103.9 15.5 8.6 0.9 1.0 1.0 2.8 2.1 13.1 32.9 0.7 0.8 0.6 106.3 4.2 15.6 2.9 0.8 63.6 3.3 0.0 47.6 12.7 0.5 87.2 17.6 0.4 0.5 42.0 41.8 0.9 1.2 21.4 9.8 0.5 20.0 21.6 50.9 0.6 11.3 0.2 0.0 0.4 0.0 0.0 47.8 0.0 0.0 0.0 0.0 1.2 55.8 8.5 10.9 0.0 0.3 34.7 0.0 21.0 0.0 0.0 2.1 1.0 0.9 15.3 0.8 21.9 0.0 0.0 37.8 0.0 7.8 0.2 0.0 28.2 0.7 9.5 0.0 15.5 12.9 81.8 0.5 19.1 5.7 14.9 0.1 40.2 8.6 9.6 15.9 0.9 0.0 15.9 0.6 0.5 40.4 23.3 0.2 0.1 5.1 0.0 0.0 44.3 11.7 8.0 1.6 27.7 0.0 47.0 18.9 176.5 65.0 49.1 58.4 42.8 51.5 53.2 51.0 32.3 30.6 37.3 34.1 49.0 100.8 3.0 63.4 40.0 4.3 0.7 8.8 1.4 1.0 1.0 0.7 0.8 0.8 0.5 1.2 0.6 1.9 22.4 13.6 0.0 68.6 41.2 78.2 84.4 158.8 0.6 33.6 49.8 3.9 8.6 69.2 0.0 0.0 37.4 92.3 4.8 7.9 3.7 0.8 67.8 2.4 2.3 11.4 15.8 0.3 25.5 10.1 3.1 100.9 18.3 1.3 0.2 2.2 1.1 3.2 0.0 0.3 47.6 32.6 6.7 12.7 0.7 0.3 15.7 10.6 0.0 18.8 2.0 208.1 0.0 0.1 12.1 3.7 0.7 52.3 46.8 3.1 6.4 62.8 0.8 0.0 1.3 5.6 30.3 23.1 179.1 55.3 14.1 74.9 0.2 9.4 95.3 TACO1 CCDC44 ENSG00000136463 "Translational activator of cytochrome c oxidase I" Q9BSH4 17 63600882-63608365 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Translation regulation" Activator "Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 87.9;Proximal enterocytes: 81.2;Proximal tubular cells: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021626, HPA021643, HPA024294" Enhanced Enhanced Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA021626: AB_1846148, HPA021643: AB_1846149, HPA024294: AB_1846150" "unprognostic (1.26e-1)" "unprognostic (2.92e-2)" "unprognostic (4.55e-3)" "unprognostic (9.82e-2)" "unprognostic (1.30e-1)" "unprognostic (9.30e-3)" "unprognostic (2.83e-1)" "unprognostic (8.09e-2)" "unprognostic (2.09e-1)" "unprognostic (7.38e-2)" "prognostic favorable (3.73e-4)" "unprognostic (1.35e-1)" "unprognostic (4.12e-3)" "unprognostic (5.21e-3)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (1.60e-2)" 12.8 18.6 16.6 8.2 17.4 8.3 10.9 18.9 18.4 8.8 17.7 17.8 18.9 11.1 9.7 13.4 9.3 5.5 42.3 16.5 17.5 30.1 69.2 7.7 10.4 17.4 17.4 8.3 12.0 18.2 9.5 8.3 17.3 9.5 16.1 9.4 11.4 9.2 61.5 11.3 16.7 9.7 16.9 11.5 15.1 12.1 17.6 9.9 9.4 55.9 12.2 11.8 9.2 16.7 39.6 61.2 19.4 20.2 16.5 23.5 25.7 28.5 26.8 56.2 44.4 40.5 23.2 32.6 21.2 33.1 38.9 35.8 43.0 41.5 52.6 17.3 58.1 32.0 29.8 72.3 45.5 38.3 21.7 29.0 28.6 48.5 51.1 20.9 29.6 24.2 44.4 24.1 26.6 71.6 44.7 28.7 16.8 42.5 62.9 28.1 47.7 40.8 33.2 27.6 29.5 32.4 19.6 64.0 55.3 25.3 53.3 29.1 26.4 39.9 29.9 27.5 50.7 25.9 27.2 38.7 30.4 26.0 29.6 2.2 9.4 9.0 9.8 8.5 10.7 7.5 13.7 9.7 10.6 9.9 12.4 10.3 1.4 17.8 7.4 7.0 10.2 9.4 16.6 17.4 18.9 18.4 16.5 17.5 17.4 17.4 17.3 16.9 17.6 16.7 9.8 3.2 6.3 2.6 12.0 2.5 8.0 21.1 8.6 8.2 7.8 10.9 54.0 17.2 11.5 14.7 2.1 32.1 8.2 32.9 54.8 29.1 15.3 8.0 11.4 14.2 13.8 17.4 4.0 27.4 28.9 14.1 16.8 6.4 9.5 16.2 8.6 87.9 26.3 6.7 3.9 21.7 12.2 10.7 3.9 46.0 11.8 9.2 10.6 2.8 22.0 15.5 14.4 1.5 3.2 30.0 25.8 11.3 10.7 11.6 81.2 109.7 9.1 13.4 19.7 10.7 14.6 26.8 13.9 18.6 4.3 19.8 10.1 40.7 32.8 7.1 TAF1C "MGC:39976, SL1, TAFI110, TAFI95" ENSG00000103168 "TATA-box binding protein associated factor, RNA polymerase I subunit C" Q15572 16 84177847-84187070 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072229 Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nucleoli fibrillar center" "HPA072229: AB_2686499" "unprognostic (9.39e-2)" "unprognostic (1.13e-1)" "unprognostic (6.86e-3)" "unprognostic (8.20e-3)" "unprognostic (4.45e-2)" "unprognostic (3.47e-2)" "unprognostic (6.21e-2)" "unprognostic (1.26e-1)" "unprognostic (2.52e-1)" "unprognostic (3.53e-1)" "prognostic favorable (1.76e-4)" "unprognostic (1.06e-2)" "prognostic unfavorable (8.08e-6)" "unprognostic (5.60e-2)" "unprognostic (2.22e-1)" "unprognostic (1.82e-1)" "prognostic favorable (3.22e-4)" 19.4 15.8 9.8 7.2 9.9 13.5 20.6 8.1 12.9 25.9 5.4 16.0 7.9 23.5 2.2 15.9 21.4 10.1 18.3 10.9 7.7 20.6 14.8 17.0 11.1 10.5 8.7 31.7 17.9 4.2 20.6 6.2 8.6 21.7 2.9 1.8 15.3 8.3 12.3 17.8 19.3 5.3 7.3 32.2 18.7 13.8 8.9 7.4 23.7 6.7 3.6 18.5 19.1 8.9 11.8 12.7 7.5 23.6 5.7 5.9 34.3 13.8 5.3 11.5 3.7 15.0 8.3 12.7 17.3 5.0 6.1 21.2 4.3 5.4 2.6 11.4 18.2 6.8 21.0 9.7 4.8 7.6 21.8 8.9 6.9 9.1 3.7 5.0 20.4 20.7 17.9 4.1 5.6 25.4 11.3 24.9 27.8 5.1 12.2 29.2 6.1 10.5 4.7 9.5 34.0 16.8 26.3 7.8 43.0 4.6 28.9 8.1 8.9 19.2 16.5 19.2 12.0 19.6 16.9 26.7 9.8 9.2 12.4 0.0 1.3 0.4 1.5 1.3 1.8 0.9 0.6 0.9 1.5 1.1 0.7 1.3 0.0 1.5 0.5 0.6 0.9 1.2 9.8 9.9 8.1 12.9 10.9 7.7 10.5 8.7 8.6 7.3 8.9 8.9 24.9 19.2 15.8 22.5 9.2 6.5 5.1 5.2 5.2 9.3 10.2 10.2 3.0 2.8 8.2 3.7 20.9 9.4 6.5 9.9 5.9 5.1 0.5 6.9 7.4 18.7 7.2 7.4 16.5 7.1 6.7 8.4 20.9 8.8 6.3 24.6 22.9 12.9 6.6 1.7 13.0 8.2 0.0 9.8 6.3 2.5 11.8 7.3 7.2 15.9 6.3 7.8 5.2 13.6 12.5 5.2 5.1 9.1 12.1 3.9 7.6 4.0 6.1 10.4 6.6 8.3 7.8 9.9 10.6 8.7 5.3 7.4 8.0 16.8 10.2 4.4 TAF4B "TAF2C2, TAFII105" ENSG00000141384 "TATA-box binding protein associated factor 4b" Q92750 18 26226445-26391685 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Oogenesis, Spermatogenesis, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 80.3;Plasma cells: 52.3;Suprabasal keratinocytes: 78.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 65.0;U-266/70: 26.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028937 Uncertain Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 30: Non-specific - Translation" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nucleoli fibrillar center" "HPA028937: AB_10603034" "unprognostic (2.46e-2)" "unprognostic (1.03e-1)" "unprognostic (1.38e-1)" "unprognostic (1.19e-3)" "unprognostic (1.74e-1)" "unprognostic (2.13e-1)" "unprognostic (5.01e-2)" "unprognostic (2.67e-1)" "unprognostic (3.29e-2)" "unprognostic (2.21e-1)" "unprognostic (4.66e-3)" "unprognostic (3.14e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (7.38e-2)" "unprognostic (9.56e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (1.72e-4)" 1.5 2.0 0.4 2.8 0.4 2.8 2.7 0.3 1.9 1.2 0.0 1.6 0.4 1.4 0.3 1.0 1.3 0.7 0.4 0.3 0.2 1.5 0.1 1.0 3.1 0.9 0.1 3.1 1.2 0.6 0.2 1.7 1.1 0.8 1.4 0.3 1.1 0.8 1.3 1.5 0.8 1.2 0.0 2.5 1.8 4.6 0.2 1.8 1.7 0.7 3.2 1.5 0.6 0.8 4.3 0.7 0.3 1.1 1.6 2.6 2.1 1.3 1.5 0.7 1.3 1.1 2.3 65.0 5.0 0.3 2.5 4.8 3.7 4.0 3.4 15.5 9.9 7.5 1.9 1.0 2.3 20.5 4.4 4.3 1.5 0.5 11.6 0.6 1.4 8.1 10.2 7.9 0.3 4.2 10.7 4.1 3.5 2.5 5.1 0.0 8.1 17.3 1.0 0.3 6.1 2.8 3.9 5.7 2.7 1.6 2.0 3.6 0.9 2.7 1.6 3.7 4.8 26.2 18.0 21.8 1.3 12.8 2.4 0.0 0.3 0.0 0.1 0.5 1.0 2.3 0.7 1.0 1.0 2.0 2.0 1.6 0.0 0.6 0.2 0.3 0.1 0.6 0.4 0.4 0.3 1.9 0.3 0.2 0.9 0.1 1.1 0.0 0.2 0.8 7.2 6.4 7.2 6.2 34.0 80.3 9.5 1.7 49.5 1.5 15.0 17.9 2.8 0.0 2.5 0.0 0.0 18.6 4.1 5.8 17.6 1.2 0.7 28.9 9.7 9.0 0.0 21.7 44.8 2.0 4.3 15.5 36.7 45.0 1.3 5.4 1.1 0.0 2.4 5.0 28.3 7.0 2.0 1.6 17.9 1.6 3.4 5.9 23.2 4.7 2.6 0.2 1.0 7.5 11.7 2.2 2.5 4.1 52.3 13.9 0.8 4.0 1.0 1.2 0.0 17.6 12.1 25.4 24.8 40.8 78.8 9.7 14.5 14.5 6.2 6.7 TAL1 "bHLHa17, SCL, TCL5" ENSG00000162367 "TAL bHLH transcription factor 1, erythroid differentiation factor" P17542 1 47216290-47232220 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.4" "Cell type enriched" "Detected in some" 4 "Erythroid cells: 151.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 153.7;HMC-1: 70.6;HUVEC TERT2: 31.2;JURKAT: 60.0;K-562: 48.9;MOLT-4: 26.3;TIME: 34.4" "Region enriched" "Detected in many" 5 "midbrain: 14.3" "Low region specificity" "Detected in many" "CAB017805, HPA047866, HPA073983" Approved Enhanced Nucleoplasm Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "CAB017805: , HPA047866: AB_2680192, HPA073983: AB_2732246" "unprognostic (2.63e-1)" "unprognostic (2.62e-2)" "unprognostic (1.22e-1)" "unprognostic (2.40e-2)" "unprognostic (1.59e-1)" "unprognostic (8.80e-3)" "unprognostic (3.95e-3)" "unprognostic (1.33e-1)" "unprognostic (4.15e-2)" "unprognostic (1.99e-2)" "unprognostic (5.42e-3)" "unprognostic (3.68e-1)" "unprognostic (1.02e-2)" "unprognostic (2.76e-2)" "unprognostic (2.19e-1)" "unprognostic (1.51e-1)" "unprognostic (1.18e-2)" 7.5 2.5 4.9 1.0 4.5 29.4 6.3 4.7 4.4 2.9 3.0 2.1 0.8 2.9 0.6 1.8 3.5 2.3 5.9 4.6 4.6 4.4 1.5 13.0 1.4 6.5 7.1 1.2 0.9 0.9 1.7 6.9 6.8 2.1 1.3 0.2 1.1 0.8 2.1 1.7 3.1 2.7 6.9 7.1 1.8 0.9 6.4 0.4 5.4 2.5 0.7 2.4 2.5 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.2 0.1 153.7 0.0 0.0 0.0 0.0 70.6 0.0 0.0 0.0 0.0 0.0 31.2 60.0 48.9 0.1 0.0 0.0 26.3 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.1 34.4 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.5 4.9 4.5 4.7 4.4 4.6 4.6 6.5 7.1 6.8 6.9 6.4 6.8 23.9 0.0 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.1 0.1 3.7 1.5 1.3 1.8 0.0 0.1 0.0 0.0 0.0 0.1 5.3 0.0 0.1 18.1 0.0 151.5 0.0 0.0 0.3 0.6 0.0 0.0 36.8 0.0 26.7 0.1 10.6 0.0 0.1 0.0 0.0 1.6 1.5 18.2 0.0 4.8 1.8 29.0 0.8 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.4 1.3 0.4 0.1 1.0 0.0 2.0 0.0 0.0 0.0 TAMALIN GRASP ENSG00000161835 "Trafficking regulator and scaffold protein tamalin" Q7Z6J2 12 52006946-52015889 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 243.8;B-cells: 60.6;dendritic cells: 114.1;Macrophages: 60.6;Plasma cells: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 37.4;TIME: 27.4;WM-115: 50.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040664, HPA062028" Approved Approved "Nuclear bodies,Vesicles" No NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "Nuclear bodies" "HPA040664: AB_10794066, HPA062028: AB_2684664" "unprognostic (1.90e-1)" "unprognostic (1.29e-2)" "unprognostic (2.48e-2)" "unprognostic (2.39e-2)" "unprognostic (2.00e-2)" "unprognostic (2.38e-2)" "unprognostic (2.23e-2)" "unprognostic (1.93e-1)" "unprognostic (2.86e-1)" "unprognostic (8.71e-2)" "unprognostic (3.16e-3)" "unprognostic (7.20e-2)" "unprognostic (3.90e-3)" "unprognostic (1.99e-3)" "unprognostic (1.44e-1)" "unprognostic (3.53e-2)" "unprognostic (2.77e-2)" 31.9 6.3 9.8 4.1 14.9 23.8 26.9 3.2 21.5 17.6 0.4 9.4 2.2 22.0 1.6 7.1 22.2 9.6 24.2 10.5 3.7 12.2 4.2 46.8 3.8 5.0 4.9 14.9 5.7 2.8 6.2 8.9 4.8 13.0 1.9 0.1 6.5 3.1 10.6 10.7 9.8 6.0 4.1 18.2 8.6 2.6 7.6 3.7 16.3 8.4 2.3 12.5 17.1 7.1 0.0 0.0 4.4 0.2 1.9 3.6 1.0 0.2 1.1 0.0 1.1 0.0 0.0 0.0 10.0 0.0 0.4 0.1 1.3 0.0 0.4 0.2 1.3 0.3 0.0 6.2 7.4 0.3 3.3 7.2 0.0 0.3 0.0 0.0 37.4 1.0 1.6 0.0 0.9 0.2 3.1 10.5 4.0 0.0 0.2 0.1 0.8 0.0 0.0 0.0 1.1 1.6 0.0 0.2 7.5 2.7 0.0 0.3 27.4 0.0 2.5 0.2 0.0 0.2 0.0 0.1 0.6 0.0 50.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 9.8 14.9 3.2 21.5 10.5 3.7 5.0 4.9 4.8 4.1 7.6 7.1 243.8 0.0 0.0 0.0 60.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.2 114.1 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.2 5.8 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 60.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.3 5.4 0.0 0.0 0.0 TAPT1 FLJ90013 ENSG00000169762 "Transmembrane anterior posterior transformation 1" Q6NXT6 4 16160505-16227410 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Chondrogenesis, Cilium biogenesis/degradation, Differentiation, Host-virus interaction, Osteogenesis" "Developmental protein, Receptor" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 114.7;Late spermatids: 163.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "REH: 45.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042567 Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" Centrosome "Nucleoplasm, Cytosol" "HPA042567: AB_2678055" "unprognostic (2.34e-1)" "unprognostic (5.84e-2)" "unprognostic (1.41e-2)" "prognostic favorable (9.75e-4)" "unprognostic (2.43e-1)" "unprognostic (2.56e-2)" "unprognostic (2.32e-3)" "unprognostic (3.15e-3)" "unprognostic (1.54e-1)" "unprognostic (6.30e-2)" "prognostic favorable (5.34e-4)" "unprognostic (7.07e-2)" "prognostic favorable (8.52e-4)" "unprognostic (9.00e-2)" "unprognostic (8.52e-2)" "unprognostic (7.25e-3)" "prognostic favorable (4.18e-4)" 7.4 15.1 17.5 6.0 18.6 25.7 10.0 17.3 22.3 8.2 15.1 8.9 6.4 10.0 9.2 6.1 9.5 6.7 9.1 17.1 17.0 12.4 30.5 11.9 9.6 18.6 17.4 8.1 8.1 13.0 8.5 6.8 18.4 7.4 8.2 24.7 7.6 6.4 35.5 7.7 7.5 9.3 17.4 8.5 7.9 11.1 17.5 12.2 11.5 19.9 8.1 7.6 6.9 19.5 4.9 3.6 6.0 7.0 8.9 6.8 2.5 7.8 6.0 7.4 8.1 4.9 8.5 31.7 8.3 5.0 10.8 4.0 5.2 4.0 9.3 2.9 6.3 6.2 5.0 5.2 8.4 12.6 6.2 4.2 7.7 7.3 5.3 9.1 3.8 19.3 9.7 14.5 7.2 3.5 18.7 10.1 4.0 9.3 8.4 45.0 8.4 5.8 12.0 5.1 10.0 8.0 7.4 6.2 9.5 4.1 11.5 12.3 7.1 6.2 4.1 4.2 10.3 13.9 12.2 24.2 12.4 30.9 7.3 1.1 0.3 0.0 0.2 0.2 0.0 1.0 0.7 0.4 0.5 2.5 0.9 0.7 0.6 0.3 0.3 0.8 0.5 0.3 17.5 18.6 17.3 22.3 17.1 17.0 18.6 17.4 18.4 17.4 17.5 19.5 12.0 32.1 62.6 47.3 20.2 9.1 6.3 4.2 4.0 24.5 15.0 9.9 14.3 10.0 8.7 7.3 114.7 4.2 16.2 11.1 3.9 6.7 79.0 14.2 12.6 12.8 14.4 16.6 42.6 8.2 3.1 10.2 8.6 12.0 2.5 17.5 8.6 46.0 4.2 70.7 43.6 9.8 4.1 10.3 18.9 163.1 9.9 11.1 16.0 45.0 6.5 33.1 8.2 60.8 68.2 9.5 9.4 15.1 8.9 7.1 10.7 8.7 14.4 62.4 6.6 17.0 11.5 33.3 5.7 7.1 8.0 7.0 10.8 16.5 9.0 6.6 TASL "CXorf21, FLJ11577" ENSG00000120280 "TLR adaptor interacting with endolysosomal SLC15A4" Q9HAI6 X 30558809-30577766 "Disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.5;lymphoid tissue: 10.9" "Cell type enriched" "Detected in some" 5 "Hofbauer cells: 22.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 7 "THP-1: 166.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001185 Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Vesicles "HPA001185: AB_1078591" "unprognostic (1.37e-1)" "unprognostic (2.52e-2)" "unprognostic (4.37e-2)" "unprognostic (2.27e-2)" "unprognostic (3.47e-2)" "unprognostic (5.25e-3)" "unprognostic (9.07e-3)" "unprognostic (5.94e-3)" "unprognostic (1.15e-1)" "unprognostic (1.40e-1)" "unprognostic (3.43e-1)" "unprognostic (3.60e-1)" "unprognostic (1.66e-3)" "unprognostic (8.99e-2)" "unprognostic (1.98e-2)" "unprognostic (3.45e-2)" "unprognostic (3.23e-2)" 1.8 1.8 0.6 10.9 0.6 19.5 2.1 0.7 1.0 1.1 1.1 3.5 4.7 0.6 0.4 1.6 0.8 3.9 0.6 0.7 0.6 1.1 2.4 4.7 10.5 1.3 1.1 0.3 0.3 0.7 0.3 2.9 1.3 1.0 3.4 0.2 1.0 0.6 0.1 0.7 3.0 2.2 0.9 9.8 3.6 0.3 1.5 5.8 0.6 0.4 10.2 4.1 0.3 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.2 0.0 0.0 13.8 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 21.5 0.0 0.0 0.0 20.5 0.0 21.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 166.0 0.0 0.0 0.0 0.0 0.1 15.0 1.6 7.5 0.0 23.9 0.0 8.6 21.9 24.1 1.6 19.8 0.3 23.0 2.0 1.1 25.3 23.6 1.8 1.3 30.6 7.1 44.4 45.9 3.4 8.0 0.6 0.6 0.7 1.0 0.7 0.6 1.3 1.1 1.3 0.9 1.5 2.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 TBCEL "LRRC35, MGC10233" ENSG00000154114 "Tubulin folding cofactor E like" Q5QJ74 11 121024072-121090775 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 104.0;Oligodendrocytes: 39.4;Plasma cells: 42.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "HPA038593, HPA038594" Approved Uncertain Cytosol NA NA 22000 "Cluster 48: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol "HPA038593: AB_10669647, HPA038594: AB_2676103" "unprognostic (9.06e-3)" "unprognostic (3.42e-2)" "unprognostic (2.65e-1)" "unprognostic (2.29e-1)" "unprognostic (5.80e-2)" "unprognostic (3.13e-1)" "unprognostic (1.22e-1)" "unprognostic (2.55e-2)" "unprognostic (1.27e-2)" "unprognostic (1.06e-2)" "unprognostic (4.20e-2)" "unprognostic (3.14e-1)" "unprognostic (8.55e-2)" "unprognostic (3.07e-3)" "unprognostic (1.86e-1)" "unprognostic (1.66e-2)" "unprognostic (1.02e-1)" 7.4 7.6 10.7 5.9 14.2 5.6 9.0 14.4 11.5 7.2 15.0 7.4 5.4 8.5 9.6 5.7 6.2 7.7 9.8 8.5 11.0 8.3 15.1 9.6 7.5 10.5 10.5 9.2 6.3 16.5 7.9 10.8 9.8 9.0 5.9 8.3 7.2 12.3 6.1 5.1 5.8 9.6 10.2 8.4 6.0 14.8 14.2 7.2 10.3 8.2 7.4 6.6 4.7 13.6 6.2 5.8 9.8 8.5 17.5 16.5 7.5 11.5 14.2 8.7 12.7 6.0 9.7 7.6 17.3 14.3 8.4 1.6 10.8 3.8 11.4 9.1 8.0 13.2 4.5 6.0 21.6 9.4 8.8 18.2 12.8 8.4 9.1 8.8 14.4 4.3 3.9 14.3 12.3 4.2 3.9 7.8 5.8 0.2 5.6 3.3 14.3 3.5 11.7 3.8 5.2 12.0 11.3 11.7 7.9 8.3 11.3 7.9 18.9 19.2 4.2 7.8 6.4 5.5 4.3 4.0 2.7 0.1 7.3 0.0 0.2 0.1 0.3 0.3 0.4 0.1 0.4 0.4 0.2 0.2 0.4 0.3 0.1 0.6 0.2 0.4 0.2 0.2 10.7 14.2 14.4 11.5 8.5 11.0 10.5 10.5 9.8 10.2 14.2 13.6 9.4 6.4 11.3 15.7 7.8 2.9 1.8 2.0 2.8 9.0 4.4 2.9 10.3 7.2 1.7 7.3 14.6 1.7 3.4 2.0 1.9 4.7 11.3 9.3 8.2 8.0 3.6 104.0 34.1 2.6 1.9 7.0 1.5 3.7 1.3 6.7 13.2 20.7 3.1 8.4 32.9 2.5 4.1 6.7 2.8 5.8 9.3 4.3 10.6 20.6 10.1 5.5 6.2 36.2 39.4 3.3 1.0 9.8 42.7 2.7 2.0 4.3 8.4 9.2 0.0 14.8 6.0 14.9 6.0 3.7 1.7 1.4 3.7 6.8 2.3 1.2 TBKBP1 "KIAA0775, ProSAPiP2" ENSG00000198933 "TBK1 binding protein 1" A7MCY6 17 47694081-47712050 "Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 62.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062347, HPA064856" Approved Approved Nucleoplasm NA Yes "Cluster 1: Neutrophils - Mixed function" "Cluster 47: Non-specific - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA062347: AB_2684744, HPA064856: AB_2685371" "unprognostic (2.14e-3)" "unprognostic (1.15e-1)" "unprognostic (2.42e-2)" "unprognostic (1.92e-2)" "unprognostic (2.39e-1)" "unprognostic (3.09e-2)" "unprognostic (3.72e-1)" "unprognostic (1.05e-1)" "unprognostic (1.51e-1)" "unprognostic (3.24e-1)" "prognostic favorable (8.14e-6)" "unprognostic (5.83e-2)" "unprognostic (1.14e-1)" "unprognostic (3.03e-1)" "unprognostic (4.22e-1)" "unprognostic (1.56e-1)" "prognostic favorable (1.59e-5)" 13.9 10.9 25.2 8.5 22.3 6.7 12.0 11.4 29.9 17.1 6.3 15.3 3.1 14.0 2.1 11.3 14.2 8.1 16.4 27.3 19.3 12.9 3.4 12.3 6.0 18.4 19.8 21.4 9.6 10.1 11.6 9.5 18.2 13.4 2.2 10.4 15.9 9.3 35.5 7.4 7.8 7.9 11.6 18.4 10.5 14.2 24.4 3.2 11.7 22.3 3.4 14.9 12.3 18.5 0.5 10.0 18.3 19.4 9.2 9.3 11.9 10.1 10.6 4.9 5.8 62.8 1.5 0.3 9.9 12.6 8.7 1.1 14.4 2.6 2.9 12.3 32.6 26.8 9.8 10.7 21.2 5.1 5.7 18.8 6.5 1.1 1.8 15.2 17.4 7.3 23.5 0.0 2.8 2.8 3.3 25.2 25.5 0.5 7.0 12.0 5.7 10.5 6.1 0.8 15.8 29.5 4.8 1.2 5.2 17.2 11.0 11.4 20.2 15.1 17.8 18.4 1.2 6.8 0.7 12.4 8.8 9.6 3.9 0.0 0.2 0.4 1.0 0.1 0.5 0.0 0.3 0.8 0.2 0.2 0.1 0.3 2.2 0.9 0.0 0.2 0.2 0.1 25.2 22.3 11.4 29.9 27.3 19.3 18.4 19.8 18.2 11.6 24.4 18.5 15.5 0.0 1.1 13.4 2.4 4.0 3.2 0.9 1.8 13.7 2.8 3.4 3.7 1.5 1.1 3.7 2.1 0.1 6.3 0.0 1.9 1.1 6.9 0.7 3.5 9.7 5.3 3.2 6.9 1.8 0.2 3.9 2.6 1.2 0.0 4.2 10.4 1.1 3.2 28.6 12.1 0.5 4.1 2.9 4.0 6.6 8.7 2.2 1.8 5.6 1.1 4.7 5.2 9.5 1.2 0.9 0.0 8.6 2.2 5.5 0.0 5.0 0.8 3.7 0.0 1.5 2.7 3.8 5.3 2.0 3.0 0.3 3.9 1.3 0.1 2.2 TBL1X "EBI, TBL1" ENSG00000101849 "Transducin beta like 1 X-linked" O60907 X 9463295-9741037 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Activator "Congenital hypothyroidism, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 103.8;Oligodendrocytes: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 18.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "CAB005363, HPA067703" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm Nucleoli "CAB005363: AB_2240272, HPA067703: AB_2685892" "prognostic unfavorable (8.50e-4)" "unprognostic (2.03e-1)" "unprognostic (2.12e-1)" "unprognostic (2.89e-2)" "unprognostic (2.44e-1)" "unprognostic (1.40e-2)" "unprognostic (2.21e-3)" "unprognostic (3.09e-1)" "unprognostic (2.70e-1)" "unprognostic (3.27e-1)" "prognostic favorable (1.32e-4)" "unprognostic (2.66e-1)" "prognostic favorable (4.58e-4)" "unprognostic (6.71e-2)" "unprognostic (6.38e-2)" "unprognostic (3.40e-3)" "unprognostic (1.53e-1)" 9.3 9.1 20.0 8.7 21.3 7.2 9.7 17.4 16.7 18.1 14.2 9.4 2.8 38.4 35.3 10.2 16.6 7.1 7.3 16.7 21.1 16.6 13.6 5.8 9.0 23.8 20.2 18.0 9.2 23.9 18.7 20.7 19.7 25.4 5.3 16.5 7.3 43.2 4.6 7.5 5.0 26.6 18.6 8.4 8.1 9.7 26.7 18.4 12.0 5.2 10.2 13.5 12.7 20.0 0.1 29.6 18.5 49.2 16.8 17.4 18.4 11.3 25.0 21.3 22.2 22.4 20.2 31.6 0.8 22.7 9.1 6.7 40.7 8.9 30.9 13.0 19.6 20.0 35.6 26.5 23.7 7.2 68.6 15.6 10.1 22.3 11.8 11.7 19.9 17.2 35.8 53.5 12.5 25.6 17.8 27.2 36.7 14.2 31.5 39.3 14.5 39.3 28.9 16.9 23.4 10.6 27.2 6.8 16.9 48.2 13.3 15.6 29.1 7.5 18.3 0.8 4.6 32.6 27.8 25.1 27.2 17.4 7.1 6.3 4.7 5.7 2.2 2.9 1.8 2.2 1.7 2.0 3.5 3.6 3.1 2.9 18.7 0.3 2.0 0.3 2.9 2.1 20.0 21.3 17.4 16.7 16.7 21.1 23.8 20.2 19.7 18.6 26.7 20.0 12.6 0.0 4.5 103.8 17.3 6.5 13.2 3.8 9.1 11.8 19.1 18.0 10.1 20.0 6.8 31.3 22.9 78.1 20.4 7.9 13.7 10.7 1.0 34.4 80.7 10.3 22.8 3.8 12.5 7.8 6.0 13.1 9.7 51.1 11.4 32.5 11.4 64.3 11.3 6.7 17.1 5.4 2.0 33.0 22.8 3.2 14.3 19.7 5.4 61.8 37.5 46.6 19.6 46.3 109.7 7.5 7.9 28.6 9.5 24.1 0.2 21.8 10.0 24.5 0.0 9.4 27.9 1.4 18.0 16.5 12.4 45.0 18.8 22.3 4.9 23.7 TCAF1 "FAM115A, KIAA0738" ENSG00000198420 "TRPM8 channel associated factor 1" Q9Y4C2 7 143851375-143902198 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 251.7;Syncytiotrophoblasts: 521.5;Theca cells: 377.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011732 Approved Approved "Nuclear bodies,Vesicles,Cell Junctions" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 28: Placenta - Pregnancy" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 52: Non-specific - Transcription" "Cell Junctions" "Nuclear bodies, Vesicles" "HPA011732: AB_2668526" "unprognostic (1.57e-1)" "unprognostic (7.28e-2)" "unprognostic (2.61e-1)" "unprognostic (3.11e-1)" "unprognostic (2.73e-1)" "unprognostic (7.00e-2)" "unprognostic (5.70e-3)" "unprognostic (3.07e-2)" "unprognostic (4.93e-2)" "prognostic favorable (5.93e-4)" "unprognostic (1.43e-1)" "unprognostic (2.69e-1)" "unprognostic (3.95e-3)" "unprognostic (6.45e-2)" "unprognostic (1.34e-1)" "unprognostic (1.55e-2)" "unprognostic (1.89e-1)" 29.0 46.5 22.7 12.9 51.4 4.7 21.7 15.1 30.3 27.5 2.7 18.8 12.2 32.2 15.2 15.1 22.2 19.3 23.7 29.4 42.7 14.8 29.3 19.0 8.4 15.4 13.4 39.9 19.4 35.1 27.2 81.1 19.8 36.2 20.3 28.0 15.8 19.8 17.5 16.9 15.8 30.6 11.5 11.7 21.7 9.4 31.0 17.1 26.8 55.7 9.0 14.8 13.4 20.1 47.2 29.0 90.1 93.7 57.9 55.7 55.1 54.3 64.9 42.4 56.3 60.5 33.0 0.2 25.2 63.3 54.5 29.7 34.8 35.7 46.5 25.7 26.0 25.7 15.7 54.0 39.7 0.3 16.2 58.2 31.5 50.0 18.4 66.8 53.4 32.2 43.2 4.5 83.2 70.7 42.3 15.9 27.6 52.0 17.4 26.0 60.7 6.2 33.7 37.5 25.6 153.1 55.5 34.2 25.7 63.7 51.5 4.0 48.8 44.6 28.5 42.2 32.7 14.0 19.2 0.4 81.9 7.6 62.3 0.4 1.5 0.9 4.7 1.8 3.3 1.6 2.8 3.1 2.9 1.6 2.4 3.0 0.4 4.4 3.1 1.4 2.3 2.5 22.7 51.4 15.1 30.3 29.4 42.7 15.4 13.4 19.8 11.5 31.0 20.1 36.3 44.8 37.1 30.3 7.3 0.0 15.0 0.0 16.5 47.7 29.4 38.6 43.0 31.5 14.9 3.7 25.0 251.7 15.2 18.7 0.0 30.9 2.4 27.6 62.7 35.1 19.4 22.1 71.2 35.6 43.7 54.6 20.9 40.5 7.6 167.5 34.6 83.6 32.9 30.3 63.1 29.3 0.0 10.5 0.0 3.5 53.1 12.2 0.0 29.0 10.8 27.5 20.6 57.3 43.7 49.9 15.4 56.4 8.4 27.3 20.1 8.9 8.0 26.7 13.1 72.1 53.3 13.3 11.7 14.1 0.0 521.5 10.4 377.5 23.5 24.3 TCAIM "C3orf23, DKFZp313N0621, TOAG-1" ENSG00000179152 "T cell activation inhibitor, mitochondrial" Q8N3R3 3 44338119-44409451 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 42.9" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 90.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.50e-1)" "unprognostic (1.61e-1)" "unprognostic (1.31e-3)" "unprognostic (1.15e-1)" "unprognostic (9.21e-2)" "unprognostic (1.98e-1)" "unprognostic (4.24e-1)" "unprognostic (1.82e-1)" "unprognostic (8.55e-2)" "unprognostic (1.93e-3)" "unprognostic (5.07e-3)" "unprognostic (5.60e-2)" "prognostic favorable (2.19e-7)" "unprognostic (4.03e-1)" "unprognostic (1.49e-1)" "unprognostic (4.65e-2)" "prognostic favorable (2.81e-4)" 8.6 8.5 7.9 6.7 8.6 4.8 6.6 12.0 10.5 5.9 8.7 9.6 8.2 6.7 8.4 10.1 6.4 9.7 19.4 7.0 8.8 24.2 42.9 9.3 6.9 9.8 9.1 8.1 5.7 11.4 3.5 9.2 9.8 9.9 9.8 10.3 4.7 5.9 22.0 7.7 9.2 8.7 8.7 7.2 9.4 5.6 9.1 8.4 7.4 18.9 7.9 9.9 4.2 10.9 15.5 7.5 8.3 10.6 13.5 10.8 17.3 14.8 17.4 15.7 16.5 7.0 35.6 22.0 10.8 10.0 11.4 7.1 8.0 16.5 17.4 9.2 8.8 15.5 10.4 16.5 23.5 25.9 14.4 12.7 33.0 15.9 17.9 14.9 21.3 22.1 19.2 12.5 16.2 10.8 25.2 13.2 7.8 17.4 17.5 5.0 9.1 16.8 36.6 24.2 8.3 20.3 16.5 22.6 24.1 14.4 17.1 15.3 18.1 9.4 11.2 24.7 22.4 8.4 16.5 16.1 21.2 20.9 16.1 14.8 7.9 10.6 3.6 10.0 4.2 2.3 4.7 3.6 10.3 3.7 3.8 5.5 3.6 3.6 10.1 5.5 9.4 4.0 7.9 8.6 12.0 10.5 7.0 8.8 9.8 9.1 9.8 8.7 9.1 10.9 12.5 9.6 16.1 38.5 7.4 10.3 9.3 12.2 12.0 18.9 11.1 8.3 30.1 24.3 10.5 14.7 12.5 13.6 14.5 12.0 60.7 23.6 3.3 10.3 7.8 11.6 6.0 7.2 55.8 20.9 21.0 7.5 12.2 17.7 21.0 15.1 15.0 47.7 20.0 25.2 90.4 17.1 12.2 18.8 10.1 2.0 8.7 17.6 7.2 20.6 16.0 17.1 9.2 42.7 47.1 25.6 14.7 4.9 7.4 10.8 11.7 46.2 11.4 13.1 13.1 8.1 12.8 6.2 11.0 16.8 9.5 13.4 8.2 14.6 17.3 13.4 TCEA2 TFIIS ENSG00000171703 "Transcription elongation factor A2" Q15560 20 64049836-64072347 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 173.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043836 Approved Supported Nucleoplasm,Centrosome NA NA "Cluster 37: B-cells - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Centrosome "HPA043836: AB_2678694" "unprognostic (6.51e-2)" "unprognostic (2.02e-1)" "unprognostic (3.91e-2)" "unprognostic (2.16e-2)" "unprognostic (2.80e-1)" "unprognostic (4.91e-3)" "unprognostic (2.38e-1)" "unprognostic (2.91e-1)" "unprognostic (1.65e-3)" "unprognostic (9.03e-3)" "unprognostic (2.49e-2)" "unprognostic (9.67e-2)" "unprognostic (1.17e-1)" "unprognostic (3.81e-3)" "unprognostic (2.70e-1)" "unprognostic (2.28e-1)" "unprognostic (3.79e-1)" 32.9 31.0 63.0 9.7 62.9 8.5 32.1 58.0 105.9 45.8 32.9 43.7 6.2 42.7 13.2 14.2 42.0 16.7 40.1 63.4 61.6 39.7 56.9 23.9 12.8 70.5 61.8 55.8 19.3 31.0 57.7 17.5 71.8 39.2 3.2 12.1 22.2 25.3 41.6 24.7 21.6 14.0 54.2 30.7 25.8 91.9 62.5 15.4 38.5 14.0 6.0 38.2 31.6 62.8 17.1 18.7 29.7 50.2 26.5 15.8 11.5 16.8 20.0 31.4 15.0 11.4 30.5 19.4 38.6 21.8 18.0 45.8 12.3 15.5 6.1 12.0 21.8 7.2 37.3 29.1 38.8 8.3 9.9 24.9 13.4 8.1 10.3 43.9 21.6 24.4 12.8 35.5 9.7 41.5 34.4 41.5 18.4 22.8 44.7 32.1 21.7 51.0 17.1 12.2 28.5 48.4 18.0 12.0 46.3 9.8 34.0 21.3 30.7 56.2 28.3 31.5 10.2 40.2 28.4 10.7 50.1 9.4 11.5 1.6 1.0 3.2 2.2 1.2 0.9 7.5 1.9 1.6 1.3 2.8 3.3 2.1 0.5 2.6 1.9 2.1 3.9 1.0 63.0 62.9 58.0 105.9 63.4 61.6 70.5 61.8 71.8 54.2 62.5 62.8 43.3 0.0 3.1 20.5 34.5 22.6 38.3 17.6 38.7 54.1 44.9 64.0 31.0 30.0 11.5 71.7 27.1 27.6 13.6 0.6 107.6 35.6 123.6 30.8 44.3 40.7 19.1 5.7 21.9 16.0 13.4 43.9 13.7 21.0 2.5 62.8 47.5 47.6 17.4 65.6 19.0 2.8 16.2 16.8 23.7 173.1 51.9 20.5 62.2 7.5 18.4 123.3 10.3 8.5 17.0 24.3 2.1 49.2 14.7 31.2 11.6 115.6 16.1 37.1 26.3 43.2 48.9 126.1 39.0 13.2 20.2 20.8 18.7 42.3 3.6 25.9 TCF15 "bHLHa40, EC2, PARAXIS" ENSG00000125878 "Transcription factor 15" Q12870 20 603797-610398 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "heart muscle: 27.8;skeletal muscle: 13.2;tongue: 9.1" "Cell type enriched" "Detected in some" 6 "Adipocytes: 260.0" "Cancer enhanced" "Detected in many" "testis cancer: 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HEL: 10.6;HMC-1: 16.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA050998, HPA060221" Approved Supported "Nuclear speckles" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" "HPA050998: AB_2681302, HPA060221: AB_2684225" "unprognostic (2.12e-2)" "unprognostic (1.96e-2)" "unprognostic (1.58e-2)" "unprognostic (3.55e-2)" "unprognostic (1.29e-1)" "unprognostic (4.62e-2)" "unprognostic (5.57e-2)" "unprognostic (2.33e-1)" "unprognostic (2.81e-1)" "prognostic unfavorable (3.25e-4)" "unprognostic (1.52e-1)" "unprognostic (9.43e-2)" "unprognostic (1.27e-3)" "unprognostic (7.21e-2)" "unprognostic (8.56e-2)" "unprognostic (5.11e-1)" "unprognostic (6.99e-2)" 7.0 0.6 1.3 0.1 1.2 0.0 4.6 1.2 1.4 0.2 0.9 1.6 0.1 0.8 0.0 0.3 0.4 0.1 27.8 1.1 1.2 1.5 0.2 0.6 0.1 1.3 1.3 0.2 0.3 0.1 0.4 3.3 1.4 0.3 0.0 0.0 0.6 0.0 13.2 0.2 0.5 0.2 1.3 0.0 0.6 2.0 1.3 0.0 0.5 9.1 0.0 0.9 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 2.9 10.6 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 1.5 0.0 1.3 0.0 3.0 0.0 1.4 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 1.2 1.4 1.1 1.2 1.3 1.3 1.4 1.3 1.3 1.2 260.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.6 0.5 0.6 1.0 15.6 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.7 0.2 0.2 41.2 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.6 0.0 0.1 7.1 0.0 0.1 1.7 0.5 0.0 0.0 0.0 0.4 0.2 0.0 0.5 0.0 2.8 0.0 0.1 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 13.1 3.7 23.3 2.3 0.6 0.0 0.0 0.0 0.2 0.5 0.0 0.0 TCF3 "bHLHb21, E2A, E47, ITF1, MGC129647, MGC129648, p75, VDIR" ENSG00000071564 "Transcription factor 3" P15923 19 1609290-1652615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "REH: 467.3;U-698: 597.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018351, HPA049808, HPA062476" Approved Enhanced Nucleoplasm No No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "CAB018351: AB_675504, HPA049808: AB_2680892, HPA062476: AB_2684775" "unprognostic (8.82e-2)" "unprognostic (4.74e-2)" "unprognostic (1.26e-2)" "unprognostic (1.25e-1)" "unprognostic (1.91e-2)" "unprognostic (8.25e-3)" "prognostic unfavorable (2.46e-4)" "unprognostic (2.07e-2)" "unprognostic (7.99e-2)" "unprognostic (2.35e-1)" "unprognostic (2.42e-1)" "unprognostic (9.29e-3)" "prognostic unfavorable (1.53e-4)" "unprognostic (4.87e-3)" "unprognostic (1.88e-1)" "unprognostic (3.07e-1)" "unprognostic (8.05e-2)" 23.8 17.9 20.7 49.2 20.0 72.8 26.1 18.1 22.7 33.4 21.9 32.3 35.5 29.6 16.2 28.2 25.5 19.8 22.8 19.1 17.8 27.2 18.9 25.9 86.6 22.0 19.3 35.1 28.4 10.2 26.2 17.9 20.4 27.3 18.7 11.0 26.4 12.0 19.5 32.9 48.0 14.4 18.3 62.5 27.3 74.8 20.3 68.4 31.6 12.5 61.0 27.4 27.4 21.8 83.6 48.6 146.4 139.8 18.6 49.6 50.4 51.9 48.0 67.8 60.6 89.8 68.7 421.7 53.5 50.1 12.7 98.4 87.9 69.2 42.8 253.7 52.4 43.2 71.2 115.2 44.8 105.7 56.8 34.0 75.1 52.4 39.2 64.0 82.5 176.1 163.8 146.6 46.0 158.2 301.1 107.8 187.1 65.1 49.2 467.3 61.7 104.3 46.5 78.5 119.3 175.7 50.1 55.9 70.8 53.0 63.8 191.7 103.2 87.1 90.5 116.0 94.1 353.5 173.5 597.2 63.1 140.3 80.1 3.3 1.2 1.0 3.6 1.5 3.6 10.0 2.1 3.1 2.8 10.6 2.8 4.3 0.4 2.8 3.2 12.9 2.2 1.7 20.7 20.0 18.1 22.7 19.1 17.8 22.0 19.3 20.4 18.3 20.3 21.8 17.3 6.4 9.1 14.7 33.9 13.9 5.3 10.0 4.6 12.3 16.6 16.1 10.7 4.3 10.8 1.8 27.1 4.3 26.5 14.7 1.9 11.4 8.6 9.9 20.4 13.5 16.2 32.2 3.9 6.9 8.9 12.3 14.8 16.6 7.0 27.8 9.7 4.8 7.7 5.0 5.6 16.5 16.2 8.9 12.3 5.2 13.7 9.4 10.6 6.5 8.1 9.2 10.3 3.0 7.3 17.6 13.3 10.1 31.1 13.0 16.4 6.3 2.9 13.8 19.7 8.2 16.9 5.5 46.2 9.0 13.2 2.9 12.5 10.4 20.1 8.5 TCTEX1D1 FLJ40873 ENSG00000152760 "Tctex1 domain containing 1" Q8N7M0 1 66752459-66779047 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 8.9;liver: 7.1" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 55.7;granulocytes: 25.9;Inhibitory neurons: 21.6;Respiratory ciliated cells: 104.2" "Cancer enriched" "Detected in single" 10 "glioma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HEL: 14.6;HUVEC TERT2: 13.4;THP-1: 16.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA028420 Uncertain NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 36: HEL - Hemostasis" "Cluster 49: Ciliated cells - Cilium organization" "HPA028420: AB_10603995" "unprognostic (3.54e-2)" "unprognostic (2.32e-2)" "unprognostic (3.72e-4)" "unprognostic (1.22e-1)" "unprognostic (9.65e-3)" "unprognostic (1.81e-2)" "unprognostic (1.40e-1)" "unprognostic (3.60e-2)" "unprognostic (1.01e-1)" "unprognostic (2.15e-1)" "unprognostic (2.09e-2)" "unprognostic (1.97e-1)" "unprognostic (3.53e-6)" "unprognostic (9.28e-4)" "unprognostic (2.78e-2)" "unprognostic (6.13e-3)" "unprognostic (3.65e-2)" 1.1 0.3 2.5 0.4 2.2 4.4 1.0 2.8 2.2 1.1 6.6 0.8 0.2 0.4 0.1 0.3 8.9 0.3 3.0 2.3 2.7 3.3 7.1 2.5 0.0 6.3 5.5 0.0 0.2 0.0 0.7 5.7 5.0 0.6 0.3 0.9 0.5 0.6 0.7 0.5 0.5 0.4 4.6 0.2 0.4 0.0 3.5 0.1 0.5 0.2 0.1 0.7 0.7 4.9 0.0 0.0 0.2 0.0 0.2 2.3 0.0 0.3 0.7 0.3 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.5 0.0 0.0 13.4 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.2 2.8 2.2 2.3 2.7 6.3 5.5 5.0 4.6 3.5 4.9 7.5 0.0 3.2 2.9 0.3 1.3 0.0 4.5 0.0 0.3 0.1 0.0 0.6 0.0 11.7 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.3 55.7 0.5 12.5 0.0 0.8 13.2 0.0 0.0 0.5 0.0 0.5 25.9 0.0 0.7 3.5 2.7 0.0 21.6 0.0 0.0 0.6 0.8 0.1 0.0 3.0 0.0 1.9 0.3 6.1 0.0 0.5 0.5 0.0 0.0 0.4 1.2 0.5 0.0 0.0 104.2 0.6 0.0 0.4 1.3 0.0 0.1 0.0 0.6 0.0 3.1 0.1 0.0 0.1 TECR "GPSN2, MRT14, SC2, TER" ENSG00000099797 "Trans-2,3-enoyl-CoA reductase" Q9NZ01 19 14517085-14565980 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1013.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029780, HPA056488" Supported Supported "Endoplasmic reticulum" NA NA 10000 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" "HPA029780: AB_10603348, HPA056488: AB_2683149" "unprognostic (9.73e-2)" "unprognostic (3.69e-3)" "unprognostic (1.55e-1)" "unprognostic (8.08e-3)" "unprognostic (1.20e-1)" "unprognostic (3.96e-2)" "unprognostic (3.68e-2)" "unprognostic (1.24e-1)" "unprognostic (1.36e-1)" "unprognostic (9.16e-2)" "unprognostic (1.29e-1)" "unprognostic (5.05e-2)" "unprognostic (3.65e-3)" "unprognostic (2.53e-3)" "unprognostic (2.34e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (2.60e-4)" 102.7 162.6 189.0 43.1 201.7 74.2 100.4 220.8 237.5 156.8 216.5 78.5 106.1 53.2 103.2 373.2 87.1 49.7 78.4 180.1 200.0 112.2 133.9 67.8 55.7 209.6 191.2 80.9 105.5 306.1 78.7 68.0 212.2 85.7 59.3 82.8 222.3 83.5 366.3 263.5 95.9 36.7 207.6 75.4 81.7 182.7 199.9 65.8 92.7 209.6 85.3 51.6 185.9 230.2 220.5 162.1 149.5 169.6 214.7 97.2 156.9 62.8 175.2 196.3 242.9 225.3 246.2 113.8 127.4 134.2 152.4 328.8 158.1 254.3 84.0 192.3 165.9 193.7 225.4 254.6 129.7 139.5 143.7 144.9 201.8 174.3 96.1 98.4 93.7 169.2 128.9 391.5 104.0 289.3 170.1 248.3 155.6 556.1 227.6 154.4 96.1 521.1 275.1 115.8 183.2 113.0 103.1 278.4 139.6 77.2 151.3 274.4 55.2 160.5 66.8 141.0 212.6 118.4 119.8 122.7 163.8 212.6 162.2 55.6 72.7 52.5 137.8 106.4 148.8 100.1 180.1 159.1 124.2 99.1 207.1 164.5 32.7 183.7 83.9 137.1 290.1 170.9 189.0 201.7 220.8 237.5 180.1 200.0 209.6 191.2 212.2 207.6 199.9 230.2 60.4 73.7 71.1 47.7 87.6 169.5 227.5 297.9 125.7 90.8 161.1 155.6 52.9 120.1 221.5 165.5 123.0 509.5 88.1 159.2 56.7 166.2 443.9 102.2 40.1 64.7 100.0 80.1 15.3 225.1 525.5 81.8 89.7 64.2 36.1 90.1 73.2 143.1 188.0 112.7 19.2 144.0 199.4 113.8 99.3 1013.1 72.7 77.8 163.7 18.7 61.6 577.9 103.0 12.5 46.5 104.8 128.2 60.2 206.1 110.2 343.2 202.9 213.1 177.5 65.7 68.4 286.7 215.0 134.2 255.3 239.7 486.2 117.7 116.0 216.2 196.5 TEK "CD202b, TIE-2, TIE2, VMCM, VMCM1" ENSG00000120156 "TEK receptor tyrosine kinase" Q02763 9 27109141-27230174 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 46.3" "Group enriched" "Detected in many" 10 "Adipocytes: 70.8;Endothelial cells: 73.9;Hepatic stellate cells: 122.0;Microglial cells: 38.4;Oligodendrocyte precursor cells: 137.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 90.9;NTERA-2: 45.2;TIME: 99.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010359, HPA073265" Approved Supported "Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 7750000 13000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Centriolar satellite" "CAB010359: AB_2203226, HPA073265: AB_2686592" "unprognostic (2.24e-1)" "unprognostic (1.74e-1)" "unprognostic (5.55e-2)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" "prognostic favorable (2.31e-5)" "unprognostic (7.48e-2)" "unprognostic (1.72e-2)" "unprognostic (1.41e-1)" "unprognostic (5.58e-2)" "unprognostic (2.72e-1)" "prognostic favorable (7.81e-4)" "unprognostic (7.50e-3)" "unprognostic (6.87e-3)" "unprognostic (1.83e-1)" "unprognostic (5.24e-3)" 20.1 9.1 8.1 5.8 7.0 0.2 14.0 6.1 8.4 9.3 4.3 5.0 3.7 12.4 2.3 5.3 6.7 11.2 16.8 7.1 6.8 23.0 10.5 28.8 3.7 7.2 6.6 3.5 3.5 4.4 3.0 46.3 7.6 3.8 5.4 0.7 3.1 6.2 10.5 2.8 5.5 12.7 6.8 28.8 4.0 1.4 9.4 1.8 9.1 22.9 2.8 6.9 3.9 6.8 0.3 0.0 3.5 0.0 0.4 5.6 0.1 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 2.4 0.0 1.6 0.0 0.0 1.8 0.0 2.2 0.8 0.1 90.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 45.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 18.3 0.0 0.0 99.1 0.0 0.5 9.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.1 8.4 7.1 6.8 7.2 6.6 7.6 6.8 9.4 6.8 70.8 3.2 1.3 1.3 0.4 1.5 0.0 0.0 0.0 0.0 0.3 0.5 8.6 0.0 0.6 1.8 0.0 0.4 0.4 0.0 0.0 0.0 0.6 0.6 0.8 73.9 0.0 2.7 4.3 0.0 2.8 4.2 0.0 0.7 0.0 0.3 122.0 1.3 0.3 0.0 5.0 0.0 0.0 6.7 2.2 0.9 0.6 0.4 0.0 38.4 0.0 0.1 0.0 137.7 2.1 1.3 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.2 0.0 1.6 1.9 0.1 0.4 0.3 1.3 1.4 0.5 1.8 0.0 0.0 TERB2 "C15orf43, MGC33951" ENSG00000167014 "Telomere repeat binding bouquet formation protein 2" Q8NHR7 15 44956687-44979229 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 22.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA041780 Uncertain Nucleoplasm,Nucleoli No NA "Cluster 83: Testis - Spermatogenesis" Nucleoli Nucleoplasm "HPA041780: AB_10796460" "unprognostic (1.42e-3)" "unprognostic (4.19e-2)" "unprognostic (1.29e-1)" "unprognostic (3.62e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TEX10 "bA208F1.2, FLJ20287, Ipi1" ENSG00000136891 "Testis expressed 10" Q9NXF1 9 100302077-100352942 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 53.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045434 Approved Nucleoplasm,Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm Mitochondria "HPA045434: AB_10965650" "unprognostic (2.88e-2)" "unprognostic (1.73e-2)" "unprognostic (2.80e-1)" "unprognostic (1.21e-1)" "unprognostic (8.28e-2)" "unprognostic (5.26e-2)" "prognostic unfavorable (4.46e-5)" "unprognostic (2.43e-2)" "unprognostic (3.74e-2)" "unprognostic (7.73e-2)" "unprognostic (1.43e-2)" "unprognostic (3.25e-2)" "unprognostic (2.07e-1)" "unprognostic (7.39e-2)" "unprognostic (3.27e-1)" "unprognostic (2.66e-3)" "unprognostic (9.63e-3)" 9.3 7.0 4.0 8.7 4.3 12.2 9.9 7.2 4.8 9.7 5.2 7.4 5.3 11.2 8.2 9.1 10.2 8.6 6.5 4.3 4.4 6.3 6.9 6.4 14.3 3.9 4.1 11.4 5.7 8.1 5.4 18.8 4.1 7.5 6.8 5.5 6.9 7.4 16.0 12.2 6.5 8.8 4.1 7.9 6.5 22.3 4.9 22.3 8.4 11.6 13.6 10.8 8.7 5.5 26.5 28.5 36.6 41.3 13.2 23.1 56.6 32.7 33.7 41.8 38.7 29.5 30.4 74.6 17.2 21.4 38.3 35.2 52.9 42.1 48.6 30.2 23.3 40.6 17.5 25.8 28.2 59.6 29.1 20.3 23.3 42.5 44.6 20.3 23.1 26.0 46.3 23.8 54.5 41.5 44.0 38.1 75.4 51.1 33.9 42.1 62.2 22.8 30.8 17.0 32.3 27.4 17.9 29.3 29.4 22.4 12.2 17.3 23.6 27.5 24.5 37.3 30.9 16.7 30.6 29.9 28.1 26.3 29.4 18.1 7.4 2.6 9.1 8.9 9.7 12.2 9.0 9.1 9.1 12.9 9.7 11.5 1.8 10.7 6.9 5.3 11.4 7.0 4.0 4.3 7.2 4.8 4.3 4.4 3.9 4.1 4.1 4.1 4.9 5.5 8.6 3.2 9.3 10.7 14.7 22.2 10.6 8.4 20.5 7.8 10.8 8.1 15.4 0.0 13.0 9.2 12.5 53.5 9.6 3.8 3.9 7.7 13.9 11.0 15.8 10.9 5.3 11.1 24.1 8.8 15.7 14.7 5.1 21.9 17.1 13.9 5.0 7.9 9.8 8.4 23.3 5.7 2.0 4.1 8.1 11.4 8.7 8.1 17.8 18.7 7.8 3.4 7.2 21.1 23.9 7.5 5.6 7.9 7.1 9.7 3.0 4.5 5.6 6.5 0.0 14.5 14.7 33.0 33.4 12.9 22.6 46.1 10.3 12.0 6.9 9.5 TEX2 "HT008, KIAA1738, TMEM96" ENSG00000136478 "Testis expressed 2" Q8IWB9 17 64147227-64263260 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 53.5;Late spermatids: 52.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "plasmacytoid DC: 20.6" "Lineage enriched" "Detected in many" 6 "dendritic cells: 20.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020648, HPA057116" Approved Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA020648: AB_1857908, HPA057116: AB_2683341" "unprognostic (6.13e-2)" "unprognostic (1.35e-1)" "prognostic favorable (3.90e-6)" "unprognostic (1.69e-2)" "unprognostic (3.84e-2)" "unprognostic (8.34e-2)" "unprognostic (6.97e-2)" "unprognostic (1.59e-1)" "unprognostic (1.24e-1)" "unprognostic (2.53e-1)" "unprognostic (8.39e-2)" "unprognostic (1.11e-1)" "unprognostic (7.97e-2)" "unprognostic (7.00e-2)" "unprognostic (1.87e-1)" "unprognostic (4.53e-3)" "unprognostic (5.59e-3)" 16.6 24.2 38.4 7.3 46.9 18.7 19.6 38.3 39.3 17.8 31.1 13.6 10.2 14.7 11.4 17.3 13.4 16.7 27.2 37.6 46.2 18.5 33.2 14.9 6.3 43.5 46.4 15.7 29.4 31.5 11.2 9.9 43.3 16.3 13.5 23.0 19.4 17.0 45.0 15.5 10.2 14.6 40.4 12.7 13.2 53.5 44.9 8.9 40.2 41.9 6.8 10.5 11.1 44.2 32.6 15.2 9.5 19.5 44.7 26.3 11.5 44.1 49.7 39.2 27.0 14.2 7.8 11.3 11.0 55.9 24.3 15.5 17.0 53.3 44.7 16.6 11.6 76.3 9.9 27.0 16.7 22.5 12.2 19.3 29.0 26.7 54.3 27.5 19.1 18.8 21.3 13.6 29.8 36.1 20.5 10.4 5.4 25.3 26.9 12.6 85.8 16.1 22.7 14.9 14.4 24.0 21.9 55.9 24.3 52.2 26.4 19.0 22.6 36.5 21.1 28.5 25.8 14.0 20.1 7.2 14.5 21.0 33.6 0.0 3.1 0.9 1.5 1.0 1.7 0.3 1.7 1.8 2.9 0.6 1.7 1.7 0.3 3.3 2.0 20.6 1.3 1.8 38.4 46.9 38.3 39.3 37.6 46.2 43.5 46.4 43.3 40.4 44.9 44.2 8.1 3.2 8.1 27.4 3.4 8.8 6.8 5.1 16.5 4.2 17.6 13.7 33.3 8.6 6.2 12.9 6.2 2.5 14.7 10.7 1.9 4.7 53.5 6.0 10.5 8.8 12.1 15.4 41.6 8.3 2.0 7.4 16.3 4.2 3.8 12.2 8.6 30.4 12.0 10.1 35.6 11.3 6.1 11.5 3.7 52.9 6.5 9.2 7.2 17.8 2.9 7.2 1.0 33.2 39.3 6.5 4.6 12.8 10.1 7.1 7.1 8.3 8.2 17.3 0.0 12.6 7.4 22.5 8.8 14.6 8.9 1.4 3.6 9.4 10.9 5.4 TFB2M "FLJ22661, FLJ23182, Hkp1" ENSG00000162851 "Transcription factor B2, mitochondrial" Q9H5Q4 1 246540561-246566261 "Metabolic proteins, Predicted intracellular proteins" "rRNA processing, Transcription, Transcription regulation" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028482, HPA028554, HPA030265" Approved Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA028482: AB_2672633, HPA028554: AB_2732441, HPA030265: AB_10696209" "unprognostic (4.38e-2)" "unprognostic (2.45e-2)" "unprognostic (3.79e-3)" "unprognostic (5.63e-2)" "unprognostic (1.10e-1)" "unprognostic (8.13e-2)" "unprognostic (8.76e-2)" "unprognostic (1.41e-1)" "unprognostic (2.51e-2)" "unprognostic (1.68e-2)" "unprognostic (2.46e-1)" "unprognostic (6.81e-2)" "unprognostic (5.26e-2)" "unprognostic (2.27e-1)" "unprognostic (9.44e-2)" "unprognostic (6.41e-2)" "unprognostic (3.53e-2)" 11.6 23.5 3.6 9.4 3.7 24.2 12.1 6.2 5.0 8.5 6.3 12.6 11.4 7.2 9.5 10.9 8.6 7.1 14.0 3.4 3.9 21.2 37.8 6.3 13.3 3.4 3.5 6.9 15.6 10.8 6.3 9.1 3.5 8.8 12.9 5.0 11.3 7.5 22.7 9.3 9.1 8.0 3.8 7.0 10.1 8.7 3.9 9.3 13.6 24.3 13.2 13.3 6.1 4.1 33.9 31.9 12.1 21.5 14.8 21.1 42.2 24.2 24.8 26.9 24.6 39.0 31.6 59.8 36.9 24.7 17.4 28.5 29.3 25.7 36.8 23.4 11.3 30.3 18.1 34.5 24.2 54.1 26.3 21.0 30.2 23.1 25.8 14.8 21.2 20.9 89.2 19.8 23.4 15.7 27.5 24.1 53.8 58.6 32.1 27.2 23.9 72.9 24.5 36.7 26.7 53.8 23.4 41.9 82.2 13.3 30.6 51.3 15.6 18.7 22.7 26.6 63.8 57.1 102.9 47.6 23.0 52.6 23.9 0.3 5.4 1.5 9.1 5.7 11.5 11.9 8.0 9.7 12.9 12.0 10.3 8.9 1.2 14.8 9.8 11.1 12.3 5.3 3.6 3.7 6.2 5.0 3.4 3.9 3.4 3.5 3.5 3.8 3.9 4.1 11.9 6.4 9.4 4.2 17.2 53.3 13.7 27.9 31.9 3.2 12.4 11.9 16.5 14.3 18.4 16.5 10.4 24.4 13.1 7.6 29.4 13.8 1.5 17.6 12.9 13.2 11.4 8.6 8.1 15.5 28.1 10.2 18.8 22.4 14.0 7.5 5.7 33.9 11.9 0.0 7.2 14.3 6.1 9.3 7.7 3.4 6.5 7.3 5.4 1.9 6.9 6.6 7.2 6.0 5.5 11.0 10.3 4.5 12.7 17.2 7.8 39.2 15.4 3.4 13.1 14.4 12.2 13.2 21.6 21.3 44.9 21.1 10.9 17.7 19.8 10.4 TFEC "bHLHe34, TCFEC, TFECL" ENSG00000105967 "Transcription factor EC" O14948 7 115935148-116159896 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.2;kidney: 20.5;lymphoid tissue: 22.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 45.5;Kupffer cells: 56.3;Macrophages: 61.6;Microglial cells: 60.0;monocytes: 44.1;Proximal tubular cells: 77.8" "Cancer enhanced" "Detected in many" "renal cancer: 5.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "classical monocyte: 7.1;intermediate monocyte: 2.8;memory B-cell: 3.8;myeloid DC: 6.3;naive B-cell: 2.5;plasmacytoid DC: 3.3" "Group enriched" "Detected in many" 29 "B-cells: 3.8;dendritic cells: 6.3;monocytes: 7.1" "Cell line enhanced" "Detected in some" "HEL: 15.9;HUVEC TERT2: 11.0;THP-1: 21.5;TIME: 12.5;U-937: 24.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB032260, HPA063577" Approved Supported Nucleoplasm NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "CAB032260: AB_2202845, HPA063577: AB_2685047" "unprognostic (1.36e-1)" "unprognostic (1.08e-2)" "unprognostic (8.70e-2)" "unprognostic (1.91e-2)" "unprognostic (1.44e-1)" "unprognostic (2.79e-2)" "unprognostic (1.13e-1)" "unprognostic (8.26e-2)" "unprognostic (2.15e-1)" "unprognostic (6.54e-2)" "unprognostic (2.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.05e-3)" "unprognostic (2.92e-1)" "unprognostic (4.14e-2)" "unprognostic (1.51e-1)" "unprognostic (3.60e-2)" 3.5 2.4 1.3 19.2 1.2 17.2 2.6 1.5 1.6 1.9 2.1 2.7 4.2 1.4 0.6 1.0 1.0 4.9 1.0 0.8 1.7 20.5 3.1 9.9 22.1 3.3 1.9 1.3 1.0 0.4 0.6 4.7 2.7 1.0 4.2 0.1 1.3 0.9 0.3 0.4 9.7 3.1 2.7 14.6 3.0 1.6 3.7 2.8 0.9 0.4 12.6 4.0 0.6 4.8 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 3.7 0.0 1.7 0.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 11.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 21.5 12.5 2.1 0.2 1.3 0.0 5.5 0.0 0.0 0.1 24.4 1.1 0.0 7.1 0.0 0.0 2.8 0.0 3.8 0.0 0.0 6.3 2.5 0.0 0.0 0.1 0.0 0.4 3.3 0.0 1.5 1.3 1.2 1.5 1.6 0.8 1.7 3.3 1.9 2.7 2.7 3.7 4.8 0.5 0.0 2.2 0.3 18.1 0.5 0.0 0.0 0.0 0.0 0.3 0.8 0.8 1.5 0.0 3.7 0.0 0.2 8.3 0.0 0.0 0.0 2.4 0.0 0.0 1.7 0.0 7.2 0.6 0.0 0.3 0.4 0.0 0.0 2.5 0.0 0.0 0.0 45.5 0.0 0.5 0.4 0.0 56.3 17.8 3.8 0.0 61.6 0.0 60.0 44.1 0.0 1.0 1.0 0.1 0.1 0.0 0.0 1.3 0.1 15.6 77.8 0.0 0.0 0.0 0.3 0.1 0.3 2.5 0.1 0.4 0.8 0.8 0.1 0.7 0.1 TFPI2 "PP5, REF1, TFPI-2" ENSG00000105825 "Tissue factor pathway inhibitor 2" P48307 7 93885396-93890753 "Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "placenta: 954.6" "Cell type enhanced" "Detected in many" "Ductal cells: 1476.3;Glandular and luminal cells: 575.6;Prostatic glandular cells: 412.6;Syncytiotrophoblasts: 2184.1" "Cancer enhanced" "Detected in all" "renal cancer: 65.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 3001.0;hTEC/SVTERT24-B: 1373.4;U-138 MG: 1245.9;U-2197: 1050.8;U-87 MG: 2051.0" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 29.7" "CAB010142, HPA049158, HPA070525" Enhanced "Secreted to extracellular matrix" NA NA 51000 "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB010142: AB_628166, HPA049158: AB_2680659, HPA070525: " "prognostic favorable (8.33e-7)" "unprognostic (2.20e-2)" "unprognostic (2.10e-2)" "prognostic favorable (5.42e-4)" "unprognostic (5.19e-3)" "unprognostic (3.98e-2)" "unprognostic (1.38e-1)" "unprognostic (2.72e-2)" "unprognostic (1.15e-2)" "unprognostic (6.86e-2)" "unprognostic (7.54e-3)" "unprognostic (7.01e-2)" "prognostic unfavorable (8.53e-4)" "unprognostic (3.38e-3)" "unprognostic (3.65e-2)" "unprognostic (1.97e-1)" "unprognostic (7.91e-2)" 51.3 28.3 0.6 36.5 0.7 0.3 30.0 0.5 1.6 2.7 1.2 3.5 1.3 32.1 5.5 2.2 19.1 15.6 7.8 0.6 4.0 20.5 21.2 11.3 3.0 5.0 0.7 46.7 76.6 0.1 9.7 954.6 0.7 7.1 2.0 51.7 4.0 5.5 2.6 1.0 1.4 9.6 0.6 4.1 5.1 0.7 1.4 6.9 0.8 1.4 1.2 26.6 1.0 0.9 1.4 179.6 42.0 1.9 99.8 15.4 0.5 178.3 33.5 20.6 15.0 0.3 1.6 0.0 3001.0 47.0 43.9 18.6 1.1 216.1 24.6 2.8 1.3 0.1 10.2 0.7 545.7 0.0 0.9 9.1 10.7 1373.4 90.1 200.0 449.0 0.0 0.4 2.2 210.1 0.3 0.4 0.7 10.8 0.0 45.7 0.5 0.0 0.2 52.1 5.4 1.6 110.2 0.0 12.7 1.2 29.9 1.5 2.9 680.3 1245.9 13.2 1050.8 1.8 0.1 4.4 14.6 2051.0 0.3 140.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.7 0.5 1.6 0.6 4.0 5.0 0.7 0.7 0.6 1.4 0.9 141.3 3.2 3.9 0.0 1.2 0.6 311.3 77.9 0.6 17.5 37.2 7.9 0.5 21.5 122.9 318.2 39.6 16.1 0.6 0.0 0.0 1476.3 0.0 280.3 38.3 122.3 0.0 2.7 0.0 41.9 214.2 137.2 0.0 575.6 0.0 0.1 108.1 1.4 16.2 3.3 0.0 0.5 12.2 4.1 4.0 0.1 1.5 5.2 3.6 2.8 17.1 22.4 0.0 0.0 0.0 39.4 0.0 0.0 0.2 412.6 0.0 1.7 27.4 161.3 0.0 7.0 35.5 0.4 3.6 1.1 1.4 2184.1 4.9 0.7 0.0 35.0 TFPT "amida, FB1, INO80F" ENSG00000105619 "TCF3 fusion partner" P0C1Z6 19 54107020-54115657 "Disease related genes, Predicted intracellular proteins" "Apoptosis, DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 135.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034958, HPA058534" Approved Supported Nucleoplasm NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "HPA034958: AB_10603036, HPA058534: AB_2683745" "unprognostic (1.76e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (5.13e-4)" "unprognostic (6.56e-2)" "unprognostic (2.13e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (5.25e-4)" "unprognostic (3.85e-1)" "unprognostic (2.85e-1)" "unprognostic (2.71e-1)" "prognostic favorable (3.13e-4)" "unprognostic (1.80e-2)" "unprognostic (1.15e-1)" "unprognostic (2.00e-2)" "unprognostic (2.61e-1)" "unprognostic (3.43e-1)" "unprognostic (3.66e-2)" 12.1 15.8 27.4 8.9 25.2 10.4 12.8 23.1 41.3 11.7 18.6 15.7 9.7 11.7 4.3 10.0 9.9 7.2 16.1 26.5 24.7 12.0 10.5 12.3 10.7 24.1 25.0 9.5 8.7 9.2 10.9 8.4 24.3 22.2 4.1 5.0 13.1 5.4 19.4 13.2 12.2 6.1 20.9 19.1 14.1 9.1 24.0 13.5 11.2 10.6 6.4 12.3 9.4 28.0 23.5 28.5 18.2 12.9 6.7 9.5 11.8 25.1 15.5 23.9 24.5 17.8 23.6 20.5 20.2 12.8 12.5 11.2 10.8 19.6 7.8 43.5 52.2 30.7 27.5 20.8 39.6 16.1 34.7 11.2 9.5 18.8 15.7 11.5 18.7 30.8 19.3 45.8 9.2 30.2 34.3 47.2 11.0 34.1 19.8 30.6 10.0 15.4 10.0 35.9 19.2 17.4 9.2 38.4 45.1 5.6 14.0 48.9 37.8 52.4 19.3 7.5 36.9 33.8 48.2 18.5 20.7 40.4 34.4 10.5 9.2 6.4 15.4 10.7 14.6 9.4 19.4 20.1 19.0 9.3 16.2 17.2 6.5 21.4 3.9 43.3 26.0 11.2 27.4 25.2 23.1 41.3 26.5 24.7 24.1 25.0 24.3 20.9 24.0 28.0 25.3 16.0 7.2 5.2 12.2 17.0 9.8 25.5 12.0 10.9 31.4 32.3 2.5 12.8 28.6 22.0 2.1 22.4 30.3 22.5 15.6 21.0 9.6 27.1 8.2 29.5 15.6 7.8 5.0 27.6 29.1 11.3 11.2 13.3 15.2 20.8 37.9 9.6 135.7 0.0 4.1 35.7 32.6 28.1 41.0 5.5 12.2 43.5 39.2 1.0 49.7 17.8 25.7 2.5 3.6 55.9 18.4 17.0 13.1 31.9 23.0 24.8 46.4 12.4 6.6 7.8 16.5 11.0 16.0 5.8 17.3 26.1 22.8 41.1 16.1 13.0 THEMIS "bA325O24.3, bA325O24.4, C6orf190, C6orf207, FLJ40584, TSEPA" ENSG00000172673 "Thymocyte selection associated" Q8N1K5 6 127708072-127918631 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 32.9" "Group enriched" "Detected in some" 4 "Excitatory neurons: 47.1;Microglial cells: 15.0;T-cells: 59.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 22 "gdT-cell: 26.7;MAIT T-cell: 34.0;memory CD4 T-cell: 33.5;memory CD8 T-cell: 48.9;naive CD4 T-cell: 30.0;naive CD8 T-cell: 58.3" "Lineage enriched" "Detected in single" 88 "T-cells: 58.3" "Group enriched" "Detected in some" 4 "HDLM-2: 32.6;JURKAT: 54.1;MOLT-4: 51.6;RPMI-8226: 21.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031422, HPA031425" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" Cytosol Nucleoplasm "HPA031422: AB_2673874, HPA031425: AB_10670129" "unprognostic (1.47e-4)" "unprognostic (2.50e-3)" "unprognostic (1.31e-2)" "unprognostic (1.41e-4)" "unprognostic (1.41e-1)" "unprognostic (5.20e-3)" "unprognostic (7.48e-3)" "unprognostic (9.01e-3)" "unprognostic (1.47e-1)" "unprognostic (7.41e-3)" "unprognostic (1.24e-1)" "unprognostic (1.28e-1)" "unprognostic (2.65e-4)" "unprognostic (2.04e-1)" "unprognostic (3.91e-2)" "unprognostic (4.98e-2)" "unprognostic (1.60e-2)" 0.4 0.5 0.5 3.3 3.2 1.7 0.6 0.1 2.3 0.4 0.3 0.7 1.6 0.2 0.4 0.6 0.2 1.4 0.1 0.9 0.1 0.2 0.7 1.4 7.5 0.6 0.3 0.1 0.3 0.0 0.0 0.1 0.4 0.4 0.9 0.0 0.9 0.1 0.1 0.2 2.3 0.3 0.3 3.2 1.5 0.1 0.3 32.9 0.4 0.1 4.0 1.1 0.3 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.1 0.0 0.0 0.0 0.0 51.6 0.0 0.0 0.0 0.0 0.0 0.0 21.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 26.7 0.1 34.0 0.1 33.5 48.9 0.2 0.2 30.0 58.3 0.6 0.1 0.2 0.2 1.7 20.3 0.5 3.2 0.1 2.3 0.9 0.1 0.6 0.3 0.4 0.3 0.3 1.9 0.5 0.0 3.0 2.9 2.0 0.5 0.0 0.0 0.0 0.0 0.4 0.3 0.4 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.9 0.1 0.2 0.4 0.0 1.7 47.1 0.0 0.0 0.7 5.1 0.1 1.3 0.0 1.1 0.1 0.1 0.0 0.9 0.0 0.0 0.8 0.8 0.2 0.0 1.5 7.2 15.0 1.4 0.0 0.0 0.0 9.7 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.5 0.1 0.0 0.1 1.4 0.0 59.9 0.0 0.0 0.1 THRB "ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB1, THRB2" ENSG00000151090 "Thyroid hormone receptor beta" P10828 3 24117153-24495756 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, Deafness, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 199.2;Cone photoreceptor cells: 164.7;Excitatory neurons: 688.0;Inhibitory neurons: 631.3;Oligodendrocyte precursor cells: 329.2" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "amygdala: 7.7;basal ganglia: 15.1;cerebral cortex: 17.6;hippocampal formation: 18.5;white matter: 6.7" "Group enriched" "Detected in some" 5 "basophil: 7.2;naive B-cell: 2.2" "Group enriched" "Detected in many" 15 "B-cells: 2.2;granulocytes: 7.2" "Cell line enhanced" "Detected in many" "K-562: 45.6;RT4: 32.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002008, CAB002009, HPA061035" Approved Supported "Nuclear bodies" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear bodies" "CAB002008: , CAB002009: , HPA061035: AB_2684422" "unprognostic (1.82e-1)" "unprognostic (4.22e-1)" "unprognostic (2.83e-1)" "unprognostic (2.20e-6)" "unprognostic (3.37e-1)" "unprognostic (2.66e-2)" "unprognostic (1.93e-2)" "unprognostic (1.73e-1)" "unprognostic (5.78e-3)" "unprognostic (2.95e-2)" "unprognostic (4.43e-1)" "unprognostic (2.01e-2)" "prognostic favorable (9.46e-8)" "unprognostic (1.32e-3)" "unprognostic (6.75e-2)" "unprognostic (2.73e-2)" "unprognostic (3.34e-2)" 11.1 4.9 7.7 1.7 15.1 1.0 10.0 0.0 17.6 2.8 0.0 11.7 2.5 7.0 1.8 6.4 3.8 2.2 7.7 18.5 2.0 12.1 20.1 5.0 1.5 0.0 0.0 2.3 9.0 7.3 15.7 4.4 0.0 7.5 8.4 20.1 6.2 7.7 23.6 6.8 3.9 7.0 0.0 5.7 8.3 0.7 1.4 3.6 4.4 27.0 1.4 8.9 4.2 6.7 10.3 3.1 0.6 0.1 17.4 8.8 6.7 0.5 2.1 1.5 3.2 6.7 9.7 0.1 2.5 6.8 1.1 15.4 10.8 3.9 1.0 0.0 6.4 0.0 2.5 8.9 0.5 0.0 0.0 16.0 7.3 0.2 1.2 3.5 0.0 0.0 45.6 0.0 1.5 0.6 0.0 0.0 6.5 0.6 3.4 0.0 0.0 0.0 10.0 32.7 1.7 0.6 16.5 8.9 0.2 4.6 9.7 0.0 0.9 3.9 3.0 0.0 1.9 0.1 0.5 0.0 2.7 0.1 0.3 7.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 2.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 2.2 7.7 15.1 0.0 17.6 18.5 2.0 0.0 0.0 0.0 0.0 1.4 6.7 3.0 3.2 11.4 199.2 3.3 9.9 29.5 13.2 1.8 17.9 24.5 18.7 11.6 8.6 14.1 23.9 164.7 12.4 0.0 39.9 1.9 2.4 2.3 3.4 0.5 6.0 25.2 3.8 688.0 12.5 23.2 13.7 16.3 5.7 0.0 0.3 7.5 37.7 1.7 0.0 631.3 8.1 10.2 11.3 11.7 2.4 0.6 4.6 1.8 97.4 0.2 11.7 0.0 329.2 32.4 10.3 17.5 2.2 0.1 40.1 4.8 8.1 10.3 21.8 6.6 12.0 7.5 0.3 0.7 5.1 23.9 5.5 1.0 0.4 9.8 81.3 THSD1 TMTSP ENSG00000136114 "Thrombospondin type 1 domain containing 1" Q9NS62 13 52377167-52416373 "Disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 22.0;Astrocytes: 25.5;Basal respiratory cells: 16.5;Endothelial cells: 29.9;Hepatic stellate cells: 17.2;Microglial cells: 17.8;Spermatocytes: 18.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 19.9;HBEC3-KT: 19.9;hTCEpi: 19.0;hTERT-HME1: 19.5;HUVEC TERT2: 40.6;LHCN-M2: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012611, CAB020796" Uncertain Supported Cytosol "Intracellular and membrane" No No 1400000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB020796: , HPA012611: AB_1857990" "unprognostic (1.21e-1)" "unprognostic (7.54e-3)" "unprognostic (3.49e-2)" "unprognostic (6.39e-2)" "unprognostic (1.31e-1)" "unprognostic (1.54e-2)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (8.87e-2)" "unprognostic (3.35e-1)" "unprognostic (6.10e-3)" "unprognostic (1.55e-1)" "unprognostic (3.05e-3)" "unprognostic (8.44e-2)" "unprognostic (1.31e-1)" "unprognostic (3.35e-2)" "unprognostic (4.90e-2)" 10.0 2.0 7.9 1.0 7.4 0.2 8.7 5.5 8.5 5.3 4.5 2.8 0.7 5.2 2.8 3.1 5.1 3.3 9.0 8.2 5.5 3.0 2.2 11.5 2.1 6.0 5.4 2.1 1.4 1.4 3.4 11.3 5.8 4.1 1.4 6.8 3.9 1.9 4.5 6.3 2.7 4.7 5.6 5.9 2.1 2.1 6.4 1.4 5.0 10.4 1.6 3.8 4.5 5.9 0.9 3.9 0.5 3.5 3.1 10.3 0.8 8.4 4.1 3.2 5.1 0.1 0.7 0.3 1.0 19.9 3.1 4.4 0.0 19.9 4.9 9.3 2.9 0.5 0.0 0.0 1.9 2.1 0.6 4.1 19.0 15.4 19.5 1.8 40.6 1.2 0.0 0.3 18.6 0.0 0.7 0.4 0.3 0.2 0.9 0.6 4.3 0.0 4.5 0.2 0.1 0.7 0.2 0.1 0.8 0.2 0.4 0.3 9.6 1.0 1.7 0.0 6.3 0.6 0.1 0.1 1.8 0.6 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 7.4 5.5 8.5 8.2 5.5 6.0 5.4 5.8 5.6 6.4 5.9 22.0 0.0 1.1 25.5 0.9 1.5 1.1 16.5 0.6 8.0 1.5 3.0 3.1 0.0 1.8 1.8 2.1 5.4 3.6 0.3 3.9 0.3 1.4 0.8 1.0 29.9 0.0 0.0 3.5 0.6 1.8 6.4 1.1 0.7 0.0 1.5 17.2 2.0 3.1 0.0 3.1 0.3 0.0 1.6 1.6 0.6 3.4 0.6 5.4 17.8 0.4 1.2 1.0 3.0 0.9 0.4 0.2 3.8 0.6 1.8 0.4 0.8 1.3 3.2 6.6 4.4 2.3 18.5 10.1 1.0 1.6 3.4 0.9 0.6 0.3 0.4 THY1 CD90 ENSG00000154096 "Thy-1 cell surface antigen" P04216 11 119415476-119424985 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 286.8;smooth muscle: 304.7;urinary bladder: 216.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 141.6;Excitatory neurons: 116.0;Fibroblasts: 201.9;Inhibitory neurons: 104.1;Muller glia cells: 108.1;Proximal tubular cells: 199.9;Smooth muscle cells: 226.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 461.3;BJ: 738.4;BJ hTERT+: 832.5;fHDF/TERT166: 1330.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003733, CAB068243, CAB068244" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 14000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane" "CAB068243: AB_2665687, CAB068244: AB_2665688, HPA003733: AB_1846340" "unprognostic (9.98e-2)" "unprognostic (2.71e-1)" "unprognostic (5.13e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (6.87e-4)" "unprognostic (7.43e-2)" "unprognostic (1.43e-3)" "unprognostic (2.38e-2)" "unprognostic (1.29e-1)" "unprognostic (2.90e-3)" "unprognostic (3.38e-2)" "unprognostic (3.52e-1)" "prognostic unfavorable (2.40e-6)" "unprognostic (1.75e-2)" "unprognostic (1.90e-2)" "unprognostic (3.03e-2)" "unprognostic (1.14e-2)" 90.6 16.4 97.9 78.6 114.8 0.2 25.6 12.9 286.8 78.9 0.0 35.4 10.2 58.6 27.8 29.4 23.1 101.0 12.9 135.4 73.3 142.2 7.4 21.6 40.4 83.6 37.0 9.2 14.8 39.4 18.1 62.0 60.8 15.5 41.8 25.3 8.5 47.0 3.4 13.9 14.5 304.7 35.4 21.9 17.4 11.4 43.6 73.2 37.9 8.3 35.6 216.7 21.7 108.7 0.7 3.9 108.5 0.1 461.3 331.5 0.3 738.4 832.5 263.6 289.3 0.2 0.2 0.4 0.1 1330.6 121.9 0.9 4.3 1.1 200.7 65.1 0.0 41.5 14.4 0.0 142.7 0.0 0.2 247.5 0.0 335.6 11.6 355.2 0.3 22.6 0.0 0.6 206.5 0.1 0.6 0.1 173.9 0.0 1.4 0.5 50.7 0.3 0.1 0.2 18.1 47.9 0.1 0.4 0.2 32.9 1.0 2.1 0.0 368.6 120.9 107.3 110.1 0.3 19.7 0.4 1.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 97.9 114.8 12.9 286.8 135.4 73.3 83.6 37.0 60.8 35.4 43.6 108.7 68.2 0.0 1.8 17.3 2.1 17.7 0.3 1.7 0.0 27.2 1.6 40.0 0.9 0.0 0.0 9.2 0.0 1.9 0.2 0.0 21.5 0.9 1.0 5.1 141.6 69.2 0.0 0.0 116.0 0.0 2.6 201.9 1.5 3.2 1.3 0.0 17.5 0.1 4.0 32.0 104.1 0.0 0.0 0.0 25.0 2.7 96.3 2.7 17.8 21.5 0.0 108.1 0.0 64.3 22.7 0.4 0.0 77.5 0.1 0.3 0.0 199.9 0.0 27.5 32.9 9.3 226.6 0.3 0.6 0.2 17.6 4.0 4.5 6.2 0.0 0.6 TIE1 "JTK14, TIE" ENSG00000066056 "Tyrosine kinase with immunoglobulin like and EGF like domains 1" P35590 1 43300982-43323108 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 130.8;Endothelial cells: 108.8;Hepatic stellate cells: 128.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 2.1;NK-cell: 2.5" "Group enriched" "Detected in many" 24 "granulocytes: 2.1;NK-cells: 2.5" "Group enriched" "Detected in some" 4 "EFO-21: 106.3;HUVEC TERT2: 238.4;TIME: 210.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 87000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (7.60e-3)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "unprognostic (1.53e-3)" "unprognostic (1.19e-2)" "unprognostic (7.83e-2)" "unprognostic (2.02e-1)" "unprognostic (9.34e-2)" "unprognostic (1.91e-2)" "unprognostic (2.25e-1)" "unprognostic (1.17e-3)" "unprognostic (2.16e-2)" "unprognostic (1.89e-1)" "unprognostic (1.29e-2)" "unprognostic (2.35e-2)" 47.0 10.1 16.6 8.1 14.8 0.9 37.8 14.6 16.9 14.0 10.1 11.2 5.2 20.4 5.3 6.5 16.0 13.3 34.2 13.1 14.2 19.8 6.7 35.3 10.1 16.4 16.5 7.5 4.2 3.2 8.0 48.6 16.8 10.8 3.1 0.4 7.4 6.5 14.0 7.9 11.0 14.1 13.9 19.9 8.8 3.0 21.1 2.1 24.2 20.7 2.9 15.1 11.8 14.8 0.0 0.0 3.6 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 106.3 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 41.9 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.2 0.0 1.7 238.4 0.0 0.0 0.0 0.0 0.0 0.0 20.4 1.3 0.0 0.1 8.1 16.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.1 210.0 1.2 0.4 0.0 0.2 0.0 0.2 0.4 0.0 0.0 3.9 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 16.6 14.8 14.6 16.9 13.1 14.2 16.4 16.5 16.8 13.9 21.1 14.8 130.8 0.0 4.2 0.0 0.4 2.2 0.6 0.0 1.2 0.3 1.0 0.9 4.9 1.5 1.8 0.0 0.0 0.3 0.7 0.9 0.0 0.0 2.0 0.1 0.4 108.8 0.0 2.5 0.4 0.2 0.1 3.1 0.0 0.4 20.3 0.1 128.8 1.3 0.5 0.0 0.2 0.1 0.0 5.6 3.1 2.5 2.1 1.1 1.8 29.0 0.1 0.1 1.0 1.0 1.1 0.0 0.0 0.7 0.1 0.7 0.1 0.9 3.6 0.9 0.0 2.2 2.2 0.9 0.7 0.5 1.4 0.3 2.3 0.5 0.2 0.7 TIMD4 TIM4 ENSG00000145850 "T cell immunoglobulin and mucin domain containing 4" Q96H15 5 156919292-156963226 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 55.3;testis: 144.0" "Group enriched" "Detected in some" 23 "Early spermatids: 1336.2;Late spermatids: 1946.7" "Cancer enriched" "Detected in some" 10 "renal cancer: 6.2" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.4;naive CD4 T-cell: 1.6;naive CD8 T-cell: 1.6;T-reg: 4.0" "Lineage enriched" "Detected in single" 18 "T-cells: 4.0" "Group enriched" "Detected in some" 18 "U-266/70: 96.7;U-266/84: 28.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015625, CAB026027" Approved Approved "Plasma membrane" NA NA 32000000 "Cluster 35: T-regs - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" "CAB026027: , HPA015625: AB_1858018" "unprognostic (2.92e-1)" "unprognostic (1.06e-2)" "unprognostic (1.73e-1)" "unprognostic (2.31e-1)" "unprognostic (1.80e-1)" "unprognostic (3.01e-2)" "unprognostic (1.10e-1)" "unprognostic (3.11e-1)" "unprognostic (3.42e-1)" "unprognostic (8.42e-2)" "unprognostic (1.10e-1)" "unprognostic (6.90e-2)" "prognostic favorable (3.37e-4)" "unprognostic (1.31e-2)" "unprognostic (4.07e-1)" "unprognostic (3.27e-2)" "unprognostic (2.08e-2)" 14.9 0.4 0.4 6.9 0.3 16.1 0.4 0.3 1.4 0.1 1.8 1.1 0.4 0.0 1.3 0.1 0.1 1.3 0.7 0.5 0.4 3.4 16.3 1.6 55.3 0.5 0.4 0.0 0.2 0.1 0.0 5.0 0.5 0.3 0.8 0.0 0.2 0.0 0.1 0.3 1.7 1.0 0.3 8.0 0.2 144.0 0.5 22.4 1.1 0.0 17.4 4.8 0.1 0.5 0.1 3.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 96.7 28.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 1.3 2.4 0.0 0.0 1.6 1.6 0.0 0.0 0.0 0.0 4.0 0.7 0.4 0.3 0.3 1.4 0.5 0.4 0.5 0.4 0.5 0.3 0.5 0.5 0.1 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.4 0.4 5.9 0.1 1336.2 0.3 0.0 0.5 0.0 0.0 0.4 0.0 0.7 0.1 0.5 0.0 0.0 0.0 0.7 0.3 46.4 0.0 0.3 0.0 0.0 69.4 1.9 1946.7 14.9 1.9 0.0 2.8 0.0 0.0 1.0 0.0 0.3 0.0 0.0 10.9 6.5 0.0 0.0 0.8 0.0 0.0 13.1 0.0 0.1 16.6 8.1 0.0 0.0 0.3 1.7 0.1 0.1 0.0 TIMP1 "CLGI, EPO, TIMP" ENSG00000102265 "TIMP metallopeptidase inhibitor 1" P01033 X 47582408-47586789 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor, Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 2277.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 2325.3;Hepatic stellate cells: 2681.5;Langerhans cells: 2307.7;Leydig cells: 1776.0;Macrophages: 1705.0;Peritubular cells: 1561.7;Smooth muscle cells: 2043.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 3225.4;ASC TERT1: 4323.2;fHDF/TERT166: 2762.5;HSkMC: 2960.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB022360, HPA053417" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 127000000 520000000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "CAB022360: , HPA053417: AB_2682142" "unprognostic (5.86e-3)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.09e-4)" "unprognostic (4.68e-2)" "unprognostic (1.81e-2)" "unprognostic (1.07e-3)" "unprognostic (4.99e-2)" "unprognostic (8.24e-3)" "unprognostic (9.12e-3)" "unprognostic (9.69e-2)" "unprognostic (9.10e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (2.90e-11)" "unprognostic (1.88e-2)" "unprognostic (1.61e-1)" "unprognostic (1.92e-2)" "unprognostic (2.66e-1)" 1043.9 895.8 110.6 1713.4 110.5 122.2 253.0 114.1 329.6 630.5 160.0 228.0 68.3 342.1 237.4 130.8 570.2 1220.1 995.3 113.5 119.9 469.6 458.6 1221.2 150.4 132.9 125.2 820.8 170.1 224.1 510.7 589.3 130.1 749.1 204.0 25.9 518.6 412.7 61.8 132.4 180.0 741.1 118.9 239.9 208.9 267.7 286.5 80.3 340.0 78.9 119.7 2277.2 303.3 115.6 194.7 295.9 150.4 1850.9 3225.4 4323.2 36.4 2079.0 1728.4 632.5 514.0 118.9 360.1 1.8 269.6 2762.5 355.3 187.2 82.9 896.0 394.8 387.0 193.8 204.1 191.7 174.9 2097.2 136.6 2440.9 2960.8 227.7 1951.9 410.1 743.6 292.1 0.7 315.8 142.9 1088.6 343.1 2.5 518.0 166.8 229.8 647.9 2.5 318.3 173.8 1038.8 120.4 2.5 8.6 1243.6 8.2 276.9 277.6 15.3 257.6 284.8 943.7 1012.1 1108.3 206.3 58.8 135.0 7.4 2688.9 322.6 634.2 331.9 488.4 8.3 139.4 853.2 137.8 21.9 224.6 122.9 511.4 10.1 73.0 65.4 504.5 88.4 817.9 15.0 104.0 431.4 110.6 110.5 114.1 329.6 113.5 119.9 132.9 125.2 130.1 118.9 286.5 115.6 145.9 109.0 170.1 6.2 57.5 231.2 591.5 937.3 132.6 25.4 147.8 133.2 22.5 374.6 355.5 132.4 0.0 25.2 59.3 53.6 0.0 538.6 21.6 34.7 511.9 772.1 277.2 102.7 0.4 411.3 280.1 2325.3 53.5 66.7 491.4 163.7 2681.5 345.1 329.7 0.0 0.4 73.0 297.0 741.4 2307.7 86.9 1776.0 1705.0 512.3 6.5 289.0 141.7 73.2 8.5 0.6 802.1 42.4 1561.7 257.4 741.4 1.1 12.9 109.1 8.4 690.2 304.1 2043.5 52.8 10.6 25.8 174.7 45.0 126.5 231.9 50.5 513.7 TIMP2 CSC-21K ENSG00000035862 "TIMP metallopeptidase inhibitor 2" P16035 17 78852977-78925387 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 941.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 475.9;Late spermatids: 491.0;Leydig cells: 353.6;Peritubular cells: 770.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.6" "Group enriched" "Detected in many" 4 "granulocytes: 13.6;monocytes: 5.0" "Cell line enhanced" "Detected in many" "ASC diff: 1327.4;ASC TERT1: 1618.4;BJ hTERT+: 960.2;fHDF/TERT166: 1070.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010203 Approved "Secreted to extracellular matrix" NA NA 110000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB010203: AB_2204966" "unprognostic (1.03e-1)" "unprognostic (1.71e-2)" "unprognostic (9.81e-2)" "unprognostic (1.76e-3)" "unprognostic (3.24e-2)" "unprognostic (3.05e-1)" "unprognostic (4.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (4.73e-2)" "unprognostic (3.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.38e-3)" "unprognostic (4.62e-2)" "unprognostic (2.05e-1)" "unprognostic (2.77e-3)" 461.0 185.1 171.5 92.3 140.8 20.1 290.6 110.6 122.1 576.3 117.9 280.5 71.0 525.4 116.8 176.0 272.7 397.9 244.8 128.6 157.0 120.7 62.8 231.7 77.7 157.4 161.5 941.0 79.1 64.0 103.6 218.1 156.2 196.2 107.6 43.5 107.2 267.5 56.6 245.2 149.5 381.6 141.5 172.0 140.9 150.4 178.0 80.0 155.6 119.8 38.7 261.2 331.0 168.1 170.0 84.0 93.0 178.8 1327.4 1618.4 50.2 585.0 960.2 280.1 221.1 30.8 288.6 0.2 200.8 1070.2 307.4 32.9 29.1 25.2 291.4 3.4 16.6 0.1 156.0 48.1 392.7 2.6 1.2 641.1 12.0 276.8 44.3 722.5 375.9 54.4 0.2 0.5 292.5 19.5 176.8 29.7 16.6 34.2 122.8 118.0 213.2 73.4 178.7 2.3 47.6 290.3 366.6 170.8 776.3 111.6 86.8 42.2 450.3 744.2 140.5 438.0 102.8 84.1 74.9 1.5 171.0 32.0 367.6 0.0 5.0 7.4 0.0 3.4 0.0 0.1 0.1 0.0 2.2 0.2 0.2 0.3 13.6 0.2 4.3 1.4 0.1 0.9 171.5 140.8 110.6 122.1 128.6 157.0 157.4 161.5 156.2 141.5 178.0 168.1 147.9 112.2 34.3 24.2 18.7 98.9 9.0 5.7 9.1 37.5 9.7 37.6 41.9 52.9 20.8 25.8 8.4 4.3 6.1 46.0 0.0 78.0 143.7 17.0 190.3 115.0 7.8 12.4 9.8 22.0 87.7 475.9 17.9 24.4 7.0 97.5 259.5 7.9 208.8 3.3 107.7 14.3 12.2 177.4 171.4 491.0 353.6 184.8 275.7 96.5 87.3 39.9 5.2 60.8 143.5 83.3 6.0 770.7 33.1 10.1 12.8 0.8 5.4 12.7 92.1 111.8 171.9 8.5 7.7 5.6 75.9 14.8 17.5 96.0 2.3 6.9 TINAGL1 "ARG1, LCN7, LIECG3, P3ECSL, TINAGRP" ENSG00000142910 "Tubulointerstitial nephritis antigen like 1" Q9GZM7 1 31576485-31587686 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1235.1;Sertoli cells: 427.3;Syncytiotrophoblasts: 1946.1" "Cancer enhanced" "Detected in all" "urothelial cancer: 87.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.0" "Cell line enhanced" "Detected in many" "BEWO: 322.7;CAPAN-2: 178.9;EFO-21: 403.6;HaCaT: 181.4;HBEC3-KT: 211.9;HUVEC TERT2: 173.4;TIME: 376.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048695 Approved "Secreted to extracellular matrix" NA NA 370000 "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA048695: AB_2680497" "unprognostic (1.27e-1)" "unprognostic (2.94e-2)" "unprognostic (7.53e-2)" "unprognostic (1.80e-3)" "unprognostic (2.74e-1)" "unprognostic (1.72e-3)" "unprognostic (8.29e-3)" "unprognostic (6.02e-3)" "unprognostic (4.18e-1)" "unprognostic (6.96e-2)" "unprognostic (7.02e-3)" "unprognostic (1.22e-1)" "prognostic favorable (3.65e-6)" "unprognostic (7.42e-2)" "unprognostic (6.64e-2)" "prognostic favorable (9.64e-4)" "unprognostic (3.43e-2)" 173.7 40.8 19.0 18.5 17.7 0.9 150.5 17.9 19.9 86.8 16.4 83.2 26.7 101.8 10.7 31.0 82.4 23.9 230.7 15.2 17.9 177.7 22.7 85.7 8.5 19.6 18.3 38.8 31.0 13.2 25.3 183.6 19.8 71.2 16.5 1.0 63.8 40.6 46.6 37.0 51.6 36.5 16.4 119.6 66.4 6.2 21.2 3.8 115.1 30.6 5.3 88.4 70.2 17.1 96.6 0.2 0.0 0.5 0.8 0.2 322.7 14.9 1.9 0.7 0.4 44.5 178.9 0.2 403.6 13.4 7.0 181.4 0.2 211.9 0.1 0.7 0.1 0.1 7.3 11.5 4.5 0.1 0.5 0.2 37.9 0.0 7.6 0.1 173.4 0.1 2.4 0.4 0.0 0.0 0.7 0.6 0.9 52.6 6.1 0.4 0.1 0.4 57.0 72.6 0.4 0.5 38.0 125.6 4.2 18.8 7.5 0.3 376.6 0.3 91.6 0.7 2.8 0.4 0.5 1.6 0.2 0.2 3.3 2.0 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.2 0.2 0.8 0.4 0.1 0.1 0.1 0.0 19.0 17.7 17.9 19.9 15.2 17.9 19.6 18.3 19.8 16.4 21.2 17.1 345.4 9.6 5.8 0.7 2.7 11.0 121.5 244.1 8.0 0.0 32.0 73.0 46.7 37.1 28.6 132.4 0.0 1235.1 2.6 158.9 1.9 378.7 1.4 8.4 3.2 161.4 11.4 13.5 0.1 92.2 223.5 35.0 50.0 14.4 14.7 49.7 306.6 4.4 89.3 0.0 1.1 35.5 14.2 8.8 10.3 0.7 7.5 4.2 23.2 13.1 2.0 0.2 0.0 0.5 0.0 344.6 115.3 4.1 0.2 131.4 45.2 80.9 9.1 0.4 427.3 9.5 357.4 0.3 0.8 4.9 6.5 1946.1 3.8 2.7 59.7 219.4 TLR2 "CD282, TIL4" ENSG00000137462 "Toll like receptor 2" O60603 4 153684070-153706260 "CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 69.9;lymphoid tissue: 51.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 77.3;Kupffer cells: 117.2;Langerhans cells: 35.7;Macrophages: 101.8;Microglial cells: 33.7;monocytes: 68.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 199.6;intermediate monocyte: 178.9;myeloid DC: 121.3;neutrophil: 457.8;non-classical monocyte: 121.5" "Group enriched" "Detected in all" 49 "dendritic cells: 121.3;granulocytes: 457.8;monocytes: 199.6" "Cell line enhanced" "Detected in some" "HL-60: 11.6;HSkMC: 12.5;hTCEpi: 12.7;NB-4: 11.4;RPTEC TERT1: 13.3;RT4: 16.3;THP-1: 62.0;U-937: 11.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA060231, HPA071546" Supported Nucleoplasm,Mitochondria No NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Mitochondria" "HPA060231: , HPA071546: " "unprognostic (4.15e-1)" "unprognostic (3.29e-2)" "unprognostic (5.32e-2)" "unprognostic (1.52e-2)" "unprognostic (3.46e-2)" "unprognostic (4.88e-2)" "unprognostic (1.39e-2)" "unprognostic (4.24e-2)" "unprognostic (2.48e-1)" "unprognostic (2.02e-2)" "unprognostic (2.04e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.11e-4)" "unprognostic (7.87e-2)" "unprognostic (3.80e-3)" "unprognostic (1.42e-1)" "unprognostic (5.93e-3)" 26.8 11.8 4.3 51.7 4.4 69.9 12.5 4.6 7.5 7.9 7.6 4.6 3.9 3.3 11.8 5.4 8.2 16.3 6.1 4.0 5.3 5.1 11.3 39.9 8.8 9.5 5.9 2.5 8.8 3.4 4.0 11.4 7.9 4.7 3.3 1.5 17.2 12.3 1.7 3.5 4.9 11.7 7.1 35.9 5.2 1.9 7.4 3.6 3.4 3.7 15.4 23.6 4.0 10.1 7.1 0.1 0.3 0.0 1.0 2.9 0.0 0.0 0.5 0.5 0.8 3.3 0.4 0.0 0.8 0.0 0.0 6.4 0.6 0.4 0.3 0.1 0.1 0.2 0.0 0.8 0.1 11.6 0.9 12.5 12.7 0.0 0.1 0.8 0.0 0.0 0.0 0.1 0.1 0.1 0.0 11.4 0.7 0.0 2.7 0.3 0.0 0.0 13.3 16.3 0.0 0.3 0.7 0.1 3.3 0.4 0.0 62.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.7 11.3 1.7 48.4 199.6 1.8 0.3 178.9 0.5 0.4 1.1 0.3 121.3 1.2 1.3 0.2 457.8 5.3 121.5 1.1 0.2 76.2 4.3 4.4 4.6 7.5 4.0 5.3 9.5 5.9 7.9 7.1 7.4 10.1 1.7 6.4 77.3 0.7 1.1 1.1 1.2 18.4 1.2 0.0 9.7 2.2 1.3 2.8 19.5 3.7 0.0 0.2 0.6 0.2 0.0 5.0 0.3 1.6 0.5 2.6 0.0 3.6 0.1 3.8 0.2 1.9 2.6 4.9 3.8 0.5 1.4 1.8 17.4 0.0 0.5 0.3 0.0 117.2 35.7 1.3 0.6 101.8 1.8 33.7 68.4 0.4 1.0 1.0 0.1 3.1 0.0 0.4 1.4 3.4 1.5 1.0 7.5 0.3 13.1 0.6 5.1 0.2 1.0 1.9 1.1 0.1 2.3 0.5 0.5 2.0 TM4SF18 L6D ENSG00000163762 "Transmembrane 4 L six family member 18" Q96CE8 3 149318498-149334414 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 33.9" "Group enriched" "Detected in many" 4 "Adipocytes: 226.1;Endothelial cells: 188.9;Hepatic stellate cells: 151.0" "Cancer enhanced" "Detected in all" "renal cancer: 17.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 94.8;EFO-21: 194.9;GAMG: 38.7;HUVEC TERT2: 65.9;NTERA-2: 47.2" "Low region specificity" "Detected in many" "HPA053639, HPA069378" Approved Supported Vesicles,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles Cytosol "HPA053639: , HPA069378: AB_2686133" "unprognostic (2.25e-1)" "unprognostic (3.68e-1)" "unprognostic (4.76e-2)" "unprognostic (1.08e-1)" "unprognostic (9.11e-3)" "unprognostic (1.05e-2)" "prognostic favorable (8.63e-4)" "unprognostic (2.84e-1)" "unprognostic (6.13e-3)" "unprognostic (1.64e-1)" "unprognostic (7.90e-3)" "unprognostic (1.75e-1)" "unprognostic (5.71e-2)" "unprognostic (3.56e-3)" "unprognostic (1.65e-1)" "unprognostic (3.01e-1)" "unprognostic (1.97e-1)" 21.3 5.2 9.4 4.9 9.6 0.1 16.3 9.2 11.5 8.3 10.4 3.4 3.9 7.6 4.7 3.4 6.4 10.6 8.4 9.1 10.3 19.1 7.9 9.2 6.6 12.2 9.6 3.2 9.8 6.8 3.1 17.4 11.5 4.0 3.3 1.1 4.0 6.5 5.9 2.4 3.6 14.9 10.0 33.9 3.4 1.9 12.1 2.1 12.7 5.7 5.0 6.7 2.5 10.4 0.1 94.8 3.5 0.2 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.2 1.2 0.0 194.9 0.0 38.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.3 0.0 0.3 0.1 0.7 0.0 0.0 0.0 24.7 65.9 0.0 0.0 0.0 6.2 0.7 0.0 0.2 47.2 0.0 0.0 0.1 2.6 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.5 1.5 0.1 0.1 8.4 0.1 1.2 0.0 0.5 0.1 0.1 0.5 0.0 0.1 15.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 9.4 9.6 9.2 11.5 9.1 10.3 12.2 9.6 11.5 10.0 12.1 10.4 226.1 0.0 4.4 0.3 1.6 3.2 0.2 0.0 0.6 0.2 41.4 23.9 2.8 4.3 0.0 1.8 0.0 0.0 1.0 0.0 9.8 35.2 0.4 0.7 1.1 188.9 0.0 0.0 0.0 0.2 0.0 6.2 0.0 0.9 1.3 0.3 151.0 1.1 0.1 0.0 0.1 0.0 0.0 9.1 3.0 1.8 2.1 1.2 1.8 33.7 0.6 0.4 0.0 0.5 0.6 0.9 0.0 6.8 2.5 1.3 0.0 35.8 0.7 0.0 0.0 1.5 2.5 0.2 0.5 0.2 2.8 0.0 1.1 5.2 0.0 0.6 TM4SF4 il-TMP ENSG00000169903 "Transmembrane 4 L six family member 4" P48230 3 149474697-149503394 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "gallbladder: 945.8;intestine: 650.8;liver: 703.8" "Group enriched" "Detected in some" 17 "Cholangiocytes: 2070.3;Hepatocytes: 578.1" "Group enriched" "Detected in many" 10 "liver cancer: 249.4;pancreatic cancer: 130.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A549: 22.7;OE19: 20.3;RPTEC TERT1: 36.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA046430 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" Cytosol "HPA046430: AB_2679662" "unprognostic (1.91e-2)" "unprognostic (1.71e-1)" "unprognostic (2.15e-1)" "unprognostic (1.66e-1)" "unprognostic (2.27e-1)" "unprognostic (1.67e-1)" "unprognostic (1.33e-1)" "unprognostic (4.96e-2)" "unprognostic (2.73e-1)" "unprognostic (1.98e-1)" "unprognostic (7.60e-2)" "unprognostic (1.83e-1)" "unprognostic (4.66e-2)" "unprognostic (1.91e-2)" "unprognostic (4.97e-1)" 0.3 1.2 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 2.0 650.8 0.6 2.3 0.7 0.5 945.8 0.3 0.0 0.0 0.8 703.8 0.3 0.8 0.0 0.0 0.0 72.5 0.0 0.1 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 514.8 0.9 0.0 0.1 21.3 0.6 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 22.7 0.0 0.0 0.0 0.0 1.5 1.1 0.0 0.0 0.0 0.6 0.3 0.2 4.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.7 0.0 0.1 0.8 0.1 20.3 0.0 0.0 0.5 1.4 36.5 0.0 0.6 1.2 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.1 0.1 0.5 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.2 0.5 0.0 1.0 0.1 0.1 0.0 0.0 0.0 0.2 0.1 4.1 2070.3 0.6 0.0 0.0 0.0 0.0 0.8 0.0 25.9 1.1 3.1 0.3 0.6 3.0 13.5 0.1 2.0 0.2 0.1 10.7 3.3 0.0 0.0 7.1 578.1 0.1 0.0 0.1 41.6 0.0 11.6 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 8.2 17.5 0.0 0.3 0.0 76.6 4.8 0.1 0.0 0.0 0.0 0.7 4.1 0.3 0.0 0.0 0.1 0.5 5.6 2.0 0.2 TM7SF2 "ANG1, DHCR14A, NET47" ENSG00000149809 "Transmembrane 7 superfamily member 2" O76062 11 65111845-65116384 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 246.0" "Cell type enhanced" "Detected in all" "Granulosa cells: 482.7;Hepatocytes: 220.6;Muller glia cells: 204.7;Theca cells: 204.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 38.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 69.2;RPTEC TERT1: 86.2;T-47d: 143.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030691, HPA072704" Enhanced Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" "Endoplasmic reticulum" Vesicles "HPA030691: AB_10602480, HPA072704: AB_2686551" "unprognostic (1.62e-1)" "unprognostic (5.23e-2)" "unprognostic (1.70e-2)" "unprognostic (1.78e-1)" "unprognostic (5.74e-2)" "unprognostic (1.10e-1)" "unprognostic (5.98e-2)" "unprognostic (6.06e-2)" "unprognostic (5.72e-2)" "unprognostic (1.74e-2)" "unprognostic (7.06e-2)" "unprognostic (1.69e-1)" "prognostic favorable (8.49e-8)" "unprognostic (8.77e-2)" "unprognostic (1.90e-1)" "unprognostic (1.35e-1)" "unprognostic (3.44e-2)" 63.4 246.0 27.8 2.6 28.5 4.1 29.1 32.8 33.9 17.4 64.1 7.8 9.4 3.4 17.0 39.6 12.8 7.0 47.3 30.0 29.7 18.9 86.4 10.1 3.4 34.0 32.0 36.5 69.9 36.3 19.5 3.9 32.5 41.1 3.9 6.0 46.9 6.0 7.1 68.2 8.3 1.9 30.1 5.1 35.6 11.5 32.6 5.6 15.5 3.7 8.4 5.5 22.1 35.1 7.7 10.9 27.3 35.1 8.1 1.3 15.4 1.8 4.5 2.7 3.0 26.0 35.8 16.3 26.9 2.2 1.0 13.3 11.6 21.2 1.9 16.7 5.0 10.2 2.7 54.5 18.8 4.2 10.6 3.7 5.0 14.6 3.9 12.6 3.9 28.7 5.8 13.9 0.8 69.2 8.3 18.6 12.6 18.4 11.2 22.4 1.2 39.9 86.2 12.6 27.2 30.5 1.2 28.2 6.1 19.5 143.9 11.4 3.1 0.4 3.4 3.8 2.3 27.1 18.1 8.4 2.5 5.9 1.0 1.1 1.6 3.4 9.1 1.5 7.0 12.4 5.6 7.8 1.5 11.9 11.8 9.0 1.1 12.5 0.9 38.1 5.6 4.9 27.8 28.5 32.8 33.9 30.0 29.7 34.0 32.0 32.5 30.1 32.6 35.1 4.0 9.6 43.7 23.5 12.7 1.9 6.2 33.6 5.7 19.2 52.2 38.5 99.4 52.9 36.6 44.1 10.4 72.9 16.3 23.3 17.6 27.1 28.8 17.9 2.6 5.7 59.4 13.7 11.6 27.7 4.6 4.3 31.1 16.5 7.0 482.7 5.0 220.6 15.6 25.2 15.3 21.8 52.9 6.3 2.7 59.3 9.9 5.8 12.4 2.8 9.4 204.7 7.2 17.1 36.5 21.7 23.7 2.2 12.9 31.3 29.0 77.5 37.9 23.6 13.1 1.6 21.8 13.3 17.9 18.0 7.0 82.1 8.3 204.8 19.0 10.4 TM9SF2 P76 ENSG00000125304 "Transmembrane 9 superfamily member 2" Q99805 13 99446311-99564048 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005657 Supported NA NA 2100000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA005657: AB_1080303" "unprognostic (9.77e-3)" "unprognostic (3.51e-2)" "unprognostic (2.85e-2)" "unprognostic (1.09e-2)" "unprognostic (3.76e-1)" "prognostic unfavorable (6.40e-4)" "unprognostic (5.96e-2)" "unprognostic (1.54e-1)" "unprognostic (1.97e-1)" "unprognostic (2.99e-2)" "unprognostic (1.66e-1)" "unprognostic (5.19e-2)" "prognostic favorable (5.21e-7)" "unprognostic (6.49e-2)" "unprognostic (8.55e-2)" "unprognostic (2.20e-2)" "unprognostic (2.21e-1)" 66.6 67.2 34.4 66.7 37.4 64.6 90.6 35.9 41.4 100.2 62.5 115.8 119.4 63.6 119.0 56.1 76.6 73.6 51.0 35.8 40.3 108.4 169.4 78.6 62.1 35.9 35.1 53.2 90.2 126.8 41.5 98.2 36.6 97.8 123.7 41.9 109.6 73.2 36.3 56.6 119.3 65.7 39.8 62.4 104.1 59.6 36.9 49.7 121.2 48.3 71.3 90.0 44.4 44.9 187.3 56.7 75.8 107.8 223.2 134.8 108.2 124.1 154.5 86.6 134.8 93.1 234.7 72.1 100.0 150.1 88.4 183.1 81.1 108.7 117.8 80.8 57.8 89.6 90.9 100.2 118.0 235.8 100.0 106.2 132.4 75.1 76.8 133.2 110.4 72.8 90.7 70.0 103.0 62.8 59.1 91.9 66.3 335.7 70.0 49.3 61.0 78.7 178.9 137.3 71.7 87.5 71.7 285.6 94.8 145.5 174.0 280.5 109.1 69.6 50.7 70.5 77.8 96.6 120.8 29.0 163.8 120.0 103.0 192.4 156.4 174.9 57.7 180.5 72.8 86.9 68.4 65.3 139.6 60.1 62.8 58.4 251.3 76.0 182.1 159.6 109.6 178.1 34.4 37.4 35.9 41.4 35.8 40.3 35.9 35.1 36.6 39.8 36.9 44.9 68.9 83.3 76.3 29.0 72.5 40.9 57.3 132.8 48.9 20.6 82.9 40.5 44.0 70.1 170.7 86.5 18.8 99.3 94.5 141.1 11.7 98.6 149.2 101.0 75.6 65.4 83.0 47.9 36.6 102.7 122.8 74.6 89.2 93.9 54.5 35.2 87.4 172.9 116.0 21.9 44.4 167.9 128.1 137.6 57.2 41.8 50.1 100.7 72.9 44.0 97.4 42.7 42.2 34.2 44.8 83.4 116.7 52.3 143.1 69.0 123.5 70.8 187.7 25.3 19.7 44.1 104.1 109.7 56.3 69.8 52.1 171.4 53.2 43.2 119.4 104.0 TMBIM4 "CGI-119, GAAP, LFG4, S1R, ZPRO" ENSG00000155957 "Transmembrane BAX inhibitor motif containing 4" Q9HC24 12 66135846-66170072 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA077642 Supported "Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Golgi apparatus" "HPA077642: AB_2686849" "unprognostic (5.41e-2)" "unprognostic (1.27e-1)" "unprognostic (3.19e-1)" "unprognostic (8.14e-2)" "unprognostic (2.69e-2)" "unprognostic (5.62e-2)" "unprognostic (7.18e-3)" "unprognostic (8.51e-2)" "unprognostic (2.49e-1)" "unprognostic (1.33e-2)" "unprognostic (3.36e-1)" "unprognostic (9.93e-2)" "unprognostic (2.49e-2)" "unprognostic (3.70e-1)" "unprognostic (3.68e-2)" "unprognostic (3.75e-2)" "unprognostic (2.20e-3)" 79.7 88.6 28.0 75.3 34.3 61.5 81.4 34.0 29.7 67.3 47.6 90.5 59.5 61.0 68.6 62.6 65.8 70.1 70.8 27.1 35.6 94.0 109.6 76.7 74.5 38.5 32.1 56.7 103.5 104.7 40.1 74.2 39.1 72.8 70.2 39.7 89.3 73.7 46.7 52.2 69.8 58.5 34.7 74.4 93.3 85.1 31.0 63.1 97.9 61.5 56.0 80.0 42.9 41.5 49.1 62.4 39.7 72.8 131.4 122.7 41.9 74.4 129.1 56.7 45.8 32.8 78.7 45.6 86.3 105.2 42.6 78.9 20.1 65.7 36.6 74.5 27.3 87.7 30.0 38.6 66.6 106.9 109.2 86.9 92.8 27.7 31.1 79.0 87.2 51.8 65.9 160.3 94.3 79.5 41.1 37.5 47.4 76.1 63.3 21.5 26.5 50.8 126.8 80.3 20.1 47.6 84.5 154.5 102.3 34.2 146.3 146.7 106.0 69.1 25.9 50.5 44.8 82.7 48.5 32.2 94.8 103.7 84.1 420.7 372.7 371.6 136.0 381.4 137.9 205.9 139.7 139.4 256.2 196.6 157.9 139.1 662.3 135.3 434.3 171.7 159.8 483.9 28.0 34.3 34.0 29.7 27.1 35.6 38.5 32.1 39.1 34.7 31.0 41.5 232.8 150.6 147.2 34.0 131.3 0.0 64.1 0.0 84.2 47.8 202.2 152.1 37.0 0.0 66.2 244.6 45.9 137.0 128.2 191.4 103.7 213.8 330.6 116.2 96.4 114.5 74.7 32.0 15.8 338.1 116.9 140.7 85.1 105.8 179.0 72.7 0.0 0.0 210.7 45.4 25.2 172.4 0.0 0.0 0.0 143.8 104.4 193.2 0.0 62.8 205.5 114.1 123.6 42.7 77.0 202.9 176.9 91.0 126.8 87.9 128.9 214.5 99.1 65.9 59.2 67.8 75.7 391.0 40.8 112.5 0.0 130.8 99.3 142.7 182.2 62.8 TMBIM6 "BAXI1, BI-1, TEGT" ENSG00000139644 "Transmembrane BAX inhibitor motif containing 6" P55061 12 49707725-49764934 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy, Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1803.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 2394.6;Late spermatids: 2375.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017378 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 2: Hepatocytes - Metabolism" "HPA017378: AB_2669604" "prognostic unfavorable (3.54e-4)" "unprognostic (6.25e-2)" "unprognostic (1.90e-2)" "unprognostic (6.52e-2)" "unprognostic (8.46e-3)" "prognostic unfavorable (1.91e-4)" "unprognostic (1.37e-1)" "unprognostic (2.19e-2)" "unprognostic (1.22e-2)" "unprognostic (6.25e-2)" "unprognostic (5.91e-2)" "unprognostic (3.80e-1)" "prognostic favorable (1.00e-5)" "unprognostic (1.95e-1)" "unprognostic (9.27e-2)" "unprognostic (1.28e-1)" "unprognostic (1.54e-2)" 333.4 364.8 332.1 276.3 361.6 315.4 416.8 347.5 376.4 413.7 528.2 493.6 475.8 252.3 640.9 406.3 431.1 360.3 215.5 301.1 358.3 1144.5 1803.2 423.3 292.3 374.4 346.9 281.2 574.2 577.5 133.7 303.1 378.7 383.2 494.4 305.0 479.8 409.3 232.1 231.4 536.1 294.7 351.9 267.8 549.8 247.9 366.9 313.0 596.4 232.3 332.3 406.2 216.5 395.2 609.6 516.6 413.3 381.1 1169.3 645.1 513.6 450.2 854.0 572.0 519.7 837.6 1703.8 380.3 746.9 882.6 598.6 648.1 363.7 659.4 619.2 551.7 390.3 606.2 367.8 414.0 707.7 701.9 959.4 657.5 1511.3 640.9 925.8 809.3 481.6 461.0 556.2 1526.5 662.5 589.5 362.1 424.2 432.1 730.6 392.2 302.8 413.0 651.0 871.5 909.9 319.0 208.7 603.5 786.1 511.2 530.7 989.4 731.6 456.8 522.6 393.9 355.8 396.9 654.2 717.8 326.8 730.9 324.3 260.8 896.4 749.8 795.5 559.9 721.8 587.8 403.6 501.1 558.5 585.5 356.6 438.9 501.8 1242.0 463.8 769.5 587.0 544.8 1813.1 332.1 361.6 347.5 376.4 301.1 358.3 374.4 346.9 378.7 351.9 366.9 395.2 428.2 477.5 455.5 80.6 314.2 261.0 535.0 836.9 222.5 245.8 526.8 337.6 221.0 571.9 766.5 544.4 114.7 406.9 366.7 995.8 131.0 927.3 1504.8 340.5 240.0 321.9 294.9 232.7 43.9 816.9 913.0 336.0 325.7 501.9 257.7 194.5 358.7 2394.6 618.9 180.0 57.3 612.6 598.1 570.6 292.8 2375.1 288.6 458.2 247.3 58.1 540.3 467.7 285.3 94.5 115.5 846.7 651.3 287.3 589.8 550.0 1585.8 809.6 874.1 154.8 170.9 191.7 361.1 458.1 214.7 272.7 235.0 891.0 315.9 372.8 552.2 654.4 TMC6 "EVER1, EVIN1, LAK-4P, TNRC6C-AS1" ENSG00000141524 "Transmembrane channel like 6" Q7Z403 17 78107397-78132407 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 110.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "K-562: 108.7;SK-BR-3: 121.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051430 Uncertain NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA051430: AB_2681483" "unprognostic (6.34e-2)" "unprognostic (5.14e-2)" "unprognostic (5.55e-2)" "unprognostic (2.81e-3)" "unprognostic (3.99e-2)" "unprognostic (1.06e-2)" "unprognostic (5.36e-2)" "unprognostic (6.27e-2)" "unprognostic (1.47e-1)" "unprognostic (9.94e-2)" "unprognostic (1.74e-1)" "unprognostic (6.61e-2)" "unprognostic (1.16e-2)" "prognostic favorable (1.82e-4)" "unprognostic (2.70e-2)" "unprognostic (1.10e-2)" "prognostic favorable (3.20e-4)" 29.5 6.8 19.2 45.4 50.5 72.7 25.2 43.4 33.5 11.3 5.2 23.5 21.7 7.6 1.0 25.4 14.1 9.7 35.9 19.3 26.4 20.6 9.1 40.3 69.7 59.3 49.7 3.8 14.6 3.1 5.6 8.8 55.9 20.2 6.6 0.6 29.3 7.9 3.5 17.9 50.6 3.5 35.8 110.5 14.6 2.6 48.4 26.3 12.9 1.8 32.4 14.6 18.4 81.9 17.9 14.0 7.5 6.0 0.0 0.0 15.2 0.0 0.0 0.2 0.2 25.2 19.2 19.7 23.7 0.0 6.3 31.0 1.0 5.9 0.0 2.0 11.3 41.3 4.2 31.0 1.9 38.3 67.0 1.1 16.2 0.0 1.3 0.2 14.7 9.2 108.7 73.3 0.0 36.1 18.9 65.4 5.9 32.9 4.9 8.4 0.6 58.9 11.4 65.1 1.9 4.9 5.7 121.0 33.2 9.7 68.7 57.6 5.2 0.0 8.7 0.1 0.3 57.6 27.3 13.2 0.0 60.4 1.0 17.7 11.6 23.2 56.2 38.3 49.0 28.5 41.7 46.2 18.6 21.7 36.5 39.6 15.3 35.8 63.5 5.7 38.0 33.5 19.2 50.5 43.4 33.5 19.3 26.4 59.3 49.7 55.9 35.8 48.4 81.9 43.8 41.7 29.6 8.1 69.5 11.1 21.0 22.3 7.4 3.2 17.4 6.5 14.7 10.0 41.5 16.5 0.0 1.2 79.8 25.0 0.0 41.2 0.3 5.1 1.6 19.7 9.1 28.4 0.2 23.1 26.4 4.6 10.2 8.0 40.5 0.7 23.6 2.2 67.0 1.7 0.2 14.0 40.7 66.2 29.9 1.2 9.6 44.7 14.2 20.6 62.0 7.5 85.5 1.5 50.8 40.5 53.7 1.2 62.6 31.5 20.3 2.0 20.3 1.8 13.1 4.6 13.5 0.5 2.2 8.4 10.2 3.7 83.7 2.5 30.3 37.4 TMC8 "EVER2, EVIN2" ENSG00000167895 "Transmembrane channel like 8" Q8IU68 17 78130770-78142968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 91.8;intestine: 54.6;lymphoid tissue: 117.0" "Cell type enhanced" "Detected in many" "B-cells: 44.9;dendritic cells: 52.3;granulocytes: 41.2;Langerhans cells: 44.6;NK-cells: 85.5;T-cells: 68.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 46.3;HL-60: 63.0;HMC-1: 119.9;Karpas-707: 103.9;RPMI-8226: 66.6;U-266/70: 49.3;U-937: 51.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047387, HPA054429" Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus" "HPA047387: , HPA054429: AB_2682485" "unprognostic (8.54e-3)" "prognostic favorable (8.45e-6)" "unprognostic (1.32e-1)" "unprognostic (2.33e-3)" "unprognostic (3.59e-1)" "prognostic favorable (4.19e-5)" "unprognostic (6.38e-3)" "unprognostic (6.47e-2)" "unprognostic (2.13e-1)" "unprognostic (1.39e-1)" "unprognostic (6.06e-2)" "unprognostic (4.27e-1)" "prognostic unfavorable (1.96e-7)" "unprognostic (6.24e-2)" "unprognostic (1.01e-2)" "unprognostic (1.25e-1)" "unprognostic (2.89e-2)" 7.8 3.0 3.6 56.0 4.4 91.8 3.7 3.7 5.1 3.7 3.5 8.2 10.3 2.5 0.7 4.8 4.0 7.4 2.7 3.6 4.8 5.2 7.1 18.4 100.5 5.8 4.7 1.3 2.0 0.5 2.2 3.9 5.6 4.9 4.5 0.1 5.8 1.3 1.8 3.6 54.6 2.4 5.0 117.0 10.4 1.2 7.8 60.1 6.4 0.9 46.7 6.4 5.0 7.2 0.5 0.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.3 46.3 2.0 0.0 0.1 3.4 0.0 0.1 0.0 0.0 0.1 16.4 0.1 0.8 0.0 63.0 119.9 0.0 0.0 0.0 0.0 0.0 0.0 22.1 4.0 103.9 0.0 1.3 20.9 2.8 0.2 3.5 0.5 1.4 0.3 66.6 0.0 0.2 0.0 0.1 0.0 2.2 0.6 0.1 6.9 12.7 0.1 0.0 0.1 0.1 0.0 49.3 2.0 4.6 0.1 51.9 0.1 2.6 2.0 6.6 13.4 3.4 9.7 5.5 10.8 13.3 2.3 4.8 9.4 8.6 3.3 7.5 7.9 2.1 6.5 5.5 3.6 4.4 3.7 5.1 3.6 4.8 5.8 4.7 5.6 5.0 7.8 7.2 3.6 3.2 10.2 1.0 44.9 5.4 10.4 4.9 4.6 0.2 1.2 1.5 1.9 1.5 6.5 0.0 0.0 0.4 52.3 3.7 0.0 1.0 0.7 1.0 0.6 3.2 1.2 17.1 0.4 1.3 1.4 2.3 2.0 1.8 41.2 0.1 5.7 0.5 30.5 0.0 0.4 1.4 14.2 28.2 44.6 0.5 0.0 22.0 7.2 24.4 30.2 0.2 85.5 1.0 2.7 0.6 3.6 0.4 20.2 2.9 0.9 0.4 2.1 0.2 0.0 0.3 2.0 0.4 0.6 8.4 4.5 0.5 68.6 2.7 7.0 10.7 TMED10 "p23, P24(DELTA), p24d1, p24delta1, TMP21" ENSG00000170348 "Transmembrane p24 trafficking protein 10" P49755 14 75131469-75176612 "Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034442, CAB037251, HPA047139, HPA050539" Enhanced Supported "Golgi apparatus" NA NA 220000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "CAB034442: AB_2204336, CAB037251: AB_1841216, HPA047139: AB_2679951, HPA050539: AB_2681163" "unprognostic (2.00e-1)" "unprognostic (1.73e-2)" "unprognostic (2.02e-1)" "unprognostic (2.51e-3)" "unprognostic (4.06e-1)" "unprognostic (1.17e-3)" "unprognostic (5.88e-2)" "unprognostic (1.21e-1)" "unprognostic (3.68e-2)" "unprognostic (6.46e-3)" "unprognostic (1.01e-2)" "unprognostic (1.27e-2)" "unprognostic (1.36e-2)" "unprognostic (1.43e-1)" "unprognostic (2.82e-1)" "prognostic unfavorable (8.67e-4)" "unprognostic (2.06e-2)" 68.0 70.3 51.8 55.2 55.8 18.0 93.2 52.6 60.7 137.9 61.2 77.0 62.3 92.6 133.1 59.9 100.6 69.2 82.3 49.5 66.1 62.7 126.9 68.0 61.0 65.8 54.3 99.7 131.9 91.4 53.6 76.3 63.2 91.0 82.3 48.8 130.7 85.9 73.7 56.0 58.8 78.9 57.5 54.6 78.3 40.0 58.2 73.7 146.0 61.0 65.9 66.9 59.7 69.6 93.3 52.2 85.5 142.5 197.5 183.7 110.9 96.5 159.5 99.5 111.2 51.8 161.2 82.5 80.6 167.5 56.8 90.8 80.4 140.6 160.5 43.7 36.2 50.5 31.1 79.2 167.1 101.7 50.2 135.1 221.5 77.0 220.1 196.0 176.9 91.7 44.6 177.8 145.0 104.6 71.0 80.7 51.9 145.2 55.8 70.6 55.3 116.6 119.7 94.8 82.9 87.1 89.0 147.0 175.9 81.0 138.3 163.3 122.3 97.0 62.9 65.9 50.7 98.9 99.3 91.3 177.0 88.3 95.8 107.4 46.4 28.9 60.8 39.4 93.8 39.7 58.7 59.3 62.9 30.3 51.9 55.9 20.4 101.8 42.6 70.9 38.2 91.4 51.8 55.8 52.6 60.7 49.5 66.1 65.8 54.3 63.2 57.5 58.2 69.6 80.8 64.1 106.3 32.0 141.8 114.2 180.4 488.1 107.0 55.6 182.5 130.6 155.3 187.3 279.9 200.5 27.1 181.0 186.7 186.2 62.6 319.1 14.5 147.7 177.5 107.3 140.7 75.5 26.9 385.7 609.9 164.4 145.8 172.0 100.1 170.9 123.1 339.7 255.0 77.4 30.0 276.2 272.6 159.4 166.3 31.5 179.3 151.6 297.1 38.4 129.5 137.9 130.7 50.8 84.2 225.8 148.9 209.9 538.8 218.7 120.3 138.9 304.8 63.1 78.9 112.7 132.2 317.7 116.5 151.7 135.1 309.2 122.1 145.8 161.9 207.7 TMEM192 FLJ38482 ENSG00000170088 "Transmembrane protein 192" Q8IY95 4 165070608-165208549 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014717, HPA024110" Enhanced Supported Nucleoplasm,Endosomes,Lysosomes NA NA "Cluster 37: B-cells - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Endosomes, Lysosomes" Nucleoplasm "HPA014717: AB_1844373, HPA024110: AB_2204898" "prognostic unfavorable (9.52e-4)" "unprognostic (5.38e-3)" "unprognostic (9.16e-2)" "unprognostic (4.39e-2)" "unprognostic (2.60e-2)" "unprognostic (1.55e-2)" "unprognostic (2.91e-3)" "unprognostic (8.43e-2)" "unprognostic (2.83e-2)" "unprognostic (3.10e-1)" "unprognostic (3.27e-2)" "unprognostic (5.06e-2)" "prognostic favorable (2.33e-14)" "unprognostic (2.09e-2)" "unprognostic (1.37e-1)" "unprognostic (2.76e-2)" "unprognostic (9.30e-2)" 12.0 15.2 4.9 7.2 5.9 6.6 13.2 7.5 7.0 9.9 7.1 11.5 9.7 10.5 9.0 8.8 11.2 10.3 12.6 4.8 5.2 48.3 45.2 10.6 8.9 4.7 5.5 24.5 22.3 24.6 5.1 10.8 5.0 22.1 13.3 10.7 14.5 8.4 15.0 5.4 9.3 8.6 4.6 9.1 10.5 9.8 4.8 6.6 26.8 17.0 7.7 8.5 5.4 6.2 13.5 19.9 7.1 18.0 18.1 6.4 16.5 20.1 29.4 20.5 22.8 11.7 21.6 29.5 11.7 13.0 33.4 11.8 26.8 20.6 23.6 19.2 13.8 16.4 14.1 13.4 46.1 41.0 21.2 23.3 42.8 18.4 37.4 17.8 17.0 15.6 28.4 48.1 25.4 29.4 7.1 12.0 14.8 28.1 16.9 16.0 6.2 27.1 16.4 19.6 15.2 15.9 31.4 49.1 31.9 10.4 23.9 18.5 12.6 9.0 11.1 28.6 23.0 46.9 67.0 40.8 21.6 22.2 36.6 2.9 16.6 4.8 12.1 14.9 16.3 26.7 9.4 12.6 15.7 20.2 10.4 12.6 1.7 18.7 8.3 16.3 8.5 10.7 4.9 5.9 7.5 7.0 4.8 5.2 4.7 5.5 5.0 4.6 4.8 6.2 12.3 32.1 36.2 18.9 24.0 9.7 18.4 10.5 10.2 33.0 21.5 15.7 35.0 42.9 19.1 55.2 16.7 31.4 15.4 17.0 11.7 21.0 26.4 11.2 17.0 19.0 21.7 10.1 16.4 25.8 20.5 18.9 7.7 15.5 40.4 26.1 27.8 77.7 38.2 37.0 16.5 18.2 6.1 27.4 17.7 11.1 39.7 22.3 28.4 11.2 21.3 35.8 28.8 14.6 20.9 11.5 14.3 33.4 11.8 33.7 26.3 63.4 10.9 27.1 6.6 30.7 20.7 17.8 18.3 12.0 12.9 33.7 15.9 27.1 24.0 14.2 TMEM200B TTMB ENSG00000253304 "Transmembrane protein 200B" Q69YZ2 1 29119429-29123903 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 60.6" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 8.8;Fibroblasts: 6.1;Leydig cells: 12.8;Melanocytes: 8.8;Peritubular cells: 15.1;Sertoli cells: 6.6;Smooth muscle cells: 9.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 28.2;BJ hTERT+ SV40 Large T+: 26.7;BJ hTERT+ SV40 Large T+ RasG12V: 29.5;fHDF/TERT166: 29.0;HBF TERT88: 25.3" "Low region specificity" "Detected in all" HPA055254 Uncertain NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA055254: AB_2682760" "unprognostic (2.55e-1)" "unprognostic (2.12e-2)" "unprognostic (8.25e-3)" "unprognostic (1.39e-1)" "unprognostic (4.71e-3)" "unprognostic (6.84e-2)" "unprognostic (1.91e-1)" "unprognostic (1.52e-2)" "unprognostic (6.25e-2)" "unprognostic (1.33e-1)" "unprognostic (6.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.24e-2)" "unprognostic (1.81e-2)" "unprognostic (2.70e-1)" "unprognostic (1.12e-1)" "unprognostic (7.16e-3)" 16.8 4.4 2.0 4.0 6.3 0.0 11.8 6.9 3.3 47.2 6.6 29.5 2.3 60.6 7.8 5.6 21.5 7.3 7.0 1.9 2.4 9.4 8.4 10.5 1.2 2.2 2.1 33.3 2.5 26.1 3.6 6.5 2.2 24.6 4.1 0.3 4.1 39.7 2.2 5.8 9.2 35.1 2.0 6.4 6.4 13.3 2.6 1.0 5.0 2.6 1.3 20.9 24.3 2.1 21.0 0.0 3.4 0.0 28.2 23.4 1.1 14.4 22.6 26.7 29.5 1.1 2.3 0.0 3.5 29.0 9.8 0.4 2.3 0.0 25.3 0.1 0.9 0.1 5.7 1.8 19.6 0.0 0.1 12.5 2.7 20.1 3.9 1.1 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.3 1.9 0.0 5.8 0.0 0.0 0.0 0.3 0.1 0.0 1.7 20.7 0.0 0.1 9.5 0.0 0.0 0.0 9.4 0.4 19.9 0.4 0.0 0.0 0.0 11.6 0.0 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 6.3 6.9 3.3 1.9 2.4 2.2 2.1 2.2 2.0 2.6 2.1 2.0 3.2 0.6 0.7 0.2 1.9 0.4 0.2 2.8 0.8 0.6 1.8 1.0 1.5 0.7 0.0 2.1 0.1 0.2 0.1 0.0 0.0 0.1 1.0 8.8 1.3 0.0 0.0 0.3 0.0 0.5 6.1 0.0 0.6 0.0 0.0 1.1 1.2 0.1 0.0 0.1 0.0 0.0 0.0 1.2 2.4 12.8 0.1 8.8 1.9 0.1 0.1 0.0 0.0 0.1 0.0 0.1 15.1 0.0 0.3 0.0 5.9 0.4 1.9 6.6 1.1 9.5 0.3 0.6 0.2 0.6 0.5 0.4 0.0 0.0 0.3 TMEM205 "MBC3205, UNQ501" ENSG00000105518 "Transmembrane protein 205" Q6UW68 19 11342776-11346518 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 405.8;Hepatocytes: 520.1;Late spermatids: 662.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041504 Approved Approved "Nucleoplasm,Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "Nucleoplasm, Nuclear membrane" "HPA041504: AB_10795595" "unprognostic (2.54e-2)" "unprognostic (2.60e-2)" "unprognostic (7.19e-2)" "unprognostic (1.57e-2)" "unprognostic (6.83e-2)" "unprognostic (1.80e-1)" "unprognostic (5.04e-3)" "unprognostic (3.77e-2)" "unprognostic (1.01e-2)" "unprognostic (5.56e-3)" "unprognostic (2.70e-2)" "unprognostic (1.19e-1)" "unprognostic (8.10e-2)" "unprognostic (5.78e-2)" "unprognostic (8.18e-2)" "unprognostic (1.20e-1)" "unprognostic (1.45e-1)" 70.3 177.5 111.5 36.8 113.2 55.2 76.0 110.7 142.9 92.8 135.4 73.8 62.3 69.5 92.6 53.7 85.2 61.1 119.7 117.2 122.4 139.2 276.9 73.9 38.9 112.8 113.1 86.8 155.0 210.0 97.4 53.6 114.0 93.2 36.4 25.9 92.4 78.7 122.2 74.3 57.2 42.2 113.6 62.6 86.3 78.8 113.6 39.3 132.1 66.0 34.1 92.4 64.0 122.7 95.5 229.7 28.5 96.2 54.1 64.5 52.6 35.2 80.9 75.9 59.4 70.0 29.5 84.7 209.3 71.6 74.5 95.6 40.5 106.6 50.5 100.7 39.2 23.0 76.5 117.7 135.9 38.9 69.8 61.3 106.7 48.7 81.0 78.5 92.3 79.9 70.4 349.8 47.0 238.8 58.6 108.9 49.9 123.0 174.5 54.3 43.4 225.9 186.9 169.0 50.2 76.7 37.3 151.1 88.1 33.1 132.2 111.3 54.0 94.3 36.2 104.4 80.2 207.0 225.3 51.5 90.4 172.2 74.0 31.8 336.5 36.7 67.2 150.0 67.9 112.7 54.7 58.5 208.2 95.8 43.9 52.2 52.6 55.8 91.0 150.9 73.7 175.8 111.5 113.2 110.7 142.9 117.2 122.4 112.8 113.1 114.0 113.6 113.6 122.7 80.5 67.3 70.5 40.1 44.1 51.5 135.9 281.3 62.0 32.5 113.3 134.4 68.5 175.8 202.3 152.6 12.5 123.7 27.7 53.7 60.7 159.2 405.8 63.2 65.8 72.4 117.6 14.5 30.8 162.7 83.0 76.4 26.0 97.0 29.2 45.4 69.3 520.1 94.4 26.9 27.3 81.4 136.3 67.5 50.0 662.3 80.8 61.2 96.0 5.6 62.1 91.9 19.6 17.6 22.2 97.7 68.6 68.1 70.7 136.7 104.1 224.6 69.3 33.1 46.0 76.3 70.9 38.1 15.6 46.4 54.0 96.7 29.8 101.6 79.3 130.9 TMEM230 "C20orf30, HSPC274" ENSG00000089063 "Transmembrane protein 230" Q96A57 20 5068232-5113103 "Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 502.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009078, HPA061421" Uncertain Enhanced "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" "Endoplasmic reticulum" "HPA009078: AB_1078345, HPA061421: AB_2684513" "unprognostic (1.39e-1)" "unprognostic (3.61e-1)" "unprognostic (3.73e-1)" "unprognostic (1.28e-1)" "unprognostic (3.71e-2)" "unprognostic (9.67e-3)" "unprognostic (5.85e-3)" "unprognostic (4.34e-3)" "unprognostic (4.18e-2)" "unprognostic (1.65e-1)" "unprognostic (2.74e-1)" "unprognostic (4.07e-2)" "unprognostic (9.70e-2)" "unprognostic (2.31e-1)" "unprognostic (2.09e-1)" "unprognostic (2.84e-2)" "unprognostic (1.55e-2)" 140.5 120.1 89.7 60.4 98.6 60.4 88.4 101.9 110.7 108.3 113.6 83.9 62.3 88.9 120.4 57.3 87.1 97.7 101.4 88.2 100.2 145.7 197.8 75.8 81.0 98.9 95.1 97.4 95.1 99.3 89.5 72.5 99.1 105.5 88.7 107.4 78.9 83.1 107.1 34.4 70.2 88.9 95.3 71.8 87.6 49.7 96.0 85.6 135.5 148.3 76.6 93.3 56.6 111.8 157.2 108.1 139.1 105.2 307.1 271.6 105.6 124.0 185.4 119.9 131.4 86.0 152.4 74.8 99.5 180.7 136.6 127.1 104.5 185.2 172.3 83.6 119.6 132.6 31.5 266.3 196.3 154.9 52.8 189.3 202.4 92.2 183.3 167.0 160.1 163.6 126.1 200.3 199.2 44.7 156.9 143.8 106.3 298.8 152.4 100.4 93.2 161.5 182.5 79.4 116.8 141.7 74.6 154.8 270.0 149.0 123.9 145.6 135.7 154.7 90.5 150.1 135.2 133.2 284.3 147.5 62.5 132.2 166.3 128.9 175.4 116.7 136.5 187.1 166.3 170.7 145.8 145.3 163.8 153.1 150.8 148.6 55.7 153.9 180.6 161.2 147.6 349.2 89.7 98.6 101.9 110.7 88.2 100.2 98.9 95.1 99.1 95.3 96.0 111.8 126.6 57.7 64.6 15.3 123.4 70.4 126.7 148.7 65.4 89.6 151.7 133.7 51.3 111.5 95.1 154.5 64.6 173.4 127.8 55.0 502.9 146.6 200.3 77.1 103.2 109.5 95.8 103.7 20.2 111.2 208.8 141.6 59.1 64.1 114.1 82.8 126.7 147.5 212.8 62.2 27.7 123.1 126.1 162.9 172.9 89.5 212.2 121.9 199.3 14.0 215.6 113.9 151.4 13.0 49.6 100.2 130.0 220.4 161.7 129.6 102.0 363.2 81.9 113.3 85.5 100.4 128.0 99.4 97.5 68.1 60.5 148.0 118.2 184.2 125.6 152.1 TMEM245 "C9orf5, CG-2" ENSG00000106771 "Transmembrane protein 245" Q9H330 9 109015135-109119947 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023892 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 39: CACO-2 - Unknown function" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" "HPA023892: AB_1845828" "unprognostic (1.56e-2)" "unprognostic (1.65e-1)" "unprognostic (1.29e-1)" "unprognostic (9.58e-2)" "unprognostic (1.63e-1)" "unprognostic (6.43e-2)" "unprognostic (1.66e-1)" "unprognostic (5.96e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (2.05e-1)" "unprognostic (1.85e-1)" "prognostic favorable (4.46e-9)" "unprognostic (6.11e-2)" "unprognostic (2.44e-1)" "unprognostic (2.41e-1)" "unprognostic (2.24e-2)" 29.2 47.6 18.1 12.4 19.4 7.3 20.2 16.8 19.4 21.0 32.6 22.9 12.6 27.3 26.1 23.1 29.2 19.2 43.1 19.6 21.4 45.9 25.2 28.7 15.1 17.3 19.6 45.3 24.6 65.1 11.3 29.1 17.8 25.5 16.9 27.7 26.2 33.9 35.4 14.2 15.9 34.2 20.6 17.9 17.8 16.8 22.0 17.0 74.2 39.2 11.6 18.9 11.9 18.4 32.3 42.2 30.5 10.3 69.9 39.9 67.0 45.4 35.0 47.9 37.6 56.9 62.9 28.9 45.3 34.7 46.4 49.5 39.1 29.2 56.2 37.8 16.8 36.0 32.2 33.7 30.5 27.5 27.2 42.9 29.2 46.7 42.8 51.5 40.7 31.5 24.4 31.2 55.1 21.2 36.8 12.6 33.9 43.2 37.5 20.8 60.3 18.0 50.8 31.0 16.8 16.4 30.0 29.6 30.2 44.9 39.6 15.4 44.9 37.0 27.7 34.9 52.4 20.6 56.9 9.2 51.5 14.5 54.9 4.4 1.6 1.5 2.4 1.1 2.9 1.5 4.0 3.4 1.6 2.1 5.2 3.6 0.6 3.3 2.4 2.2 4.3 1.8 18.1 19.4 16.8 19.4 19.6 21.4 17.3 19.6 17.8 20.6 22.0 18.4 55.0 115.4 93.1 36.6 22.4 25.2 18.8 27.4 27.3 43.8 34.4 23.0 135.6 74.4 33.8 86.5 106.3 50.7 20.1 27.0 3.9 22.7 6.7 31.6 24.8 51.8 31.2 70.5 71.4 31.1 17.7 31.3 25.5 56.4 31.6 62.8 74.3 98.3 18.0 63.9 62.0 31.1 10.2 28.4 14.3 7.8 41.0 18.9 23.2 46.9 18.3 52.6 16.5 60.8 75.8 30.0 35.6 51.1 19.7 23.1 55.3 33.7 45.6 32.4 46.0 40.7 37.9 27.4 43.8 21.0 28.4 15.1 28.2 81.4 35.6 21.7 TMEM254 "bA369J21.6, C10orf57, FLJ13263" ENSG00000133678 "Transmembrane protein 254" Q8TBM7 10 80078646-80092557 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029105, HPA072613" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Nucleoplasm "HPA029105: AB_2672909, HPA072613: AB_2732205" "unprognostic (9.40e-2)" "unprognostic (1.76e-1)" "unprognostic (9.52e-2)" "unprognostic (5.74e-3)" "unprognostic (5.39e-2)" "unprognostic (6.04e-2)" "unprognostic (3.66e-1)" "unprognostic (3.90e-1)" "unprognostic (1.64e-2)" "unprognostic (1.87e-3)" "unprognostic (3.68e-2)" "unprognostic (1.46e-1)" "unprognostic (7.65e-2)" "unprognostic (2.46e-1)" "unprognostic (1.21e-1)" "unprognostic (3.45e-3)" "unprognostic (5.96e-2)" 15.2 11.9 7.9 11.1 8.3 9.4 26.5 7.3 8.3 16.0 7.0 22.6 16.3 10.7 62.1 39.5 28.0 14.0 5.7 8.0 7.0 14.8 52.8 9.4 10.4 8.0 8.7 13.0 19.0 16.5 4.4 15.6 8.5 43.1 22.3 11.2 16.6 14.2 4.4 72.3 15.4 10.4 8.3 7.8 15.0 15.5 7.5 15.4 14.8 2.9 14.6 12.4 22.7 9.3 14.4 13.8 20.0 17.2 27.1 29.7 33.4 13.5 9.3 9.0 9.7 10.6 43.5 11.0 22.1 16.9 9.3 15.2 8.9 11.5 10.0 17.5 16.5 3.0 3.8 14.3 11.2 12.8 13.0 20.3 48.6 8.9 7.3 20.6 7.7 9.1 7.9 22.9 9.4 29.8 10.7 9.9 11.0 12.6 43.2 13.2 2.8 9.7 13.5 11.9 8.0 12.1 12.6 31.4 13.3 14.8 45.1 9.1 12.1 7.8 12.8 12.0 8.0 15.8 24.7 0.8 17.8 13.6 6.6 57.3 25.0 13.0 18.1 28.6 22.3 21.3 20.2 18.8 20.7 14.3 33.8 22.6 2.8 17.5 31.5 23.1 27.2 20.5 7.9 8.3 7.3 8.3 8.0 7.0 8.0 8.7 8.5 8.3 7.5 9.3 4.6 9.6 9.6 17.6 7.3 8.2 5.9 9.7 5.2 7.9 22.6 17.5 4.4 12.8 13.7 9.2 16.7 40.9 3.8 9.0 21.5 15.7 10.5 37.6 10.0 5.4 8.4 5.9 17.2 8.7 37.2 7.6 11.2 10.5 5.7 12.9 5.7 33.4 19.4 16.8 16.4 23.7 8.2 10.3 5.8 7.5 9.3 8.5 3.6 4.7 15.2 15.7 12.3 8.5 14.8 10.3 15.3 11.7 5.2 15.6 19.6 23.1 40.2 13.3 13.1 2.6 7.1 36.8 8.7 20.9 24.0 22.7 6.9 11.2 18.1 8.4 TMEM255B "FAM70B, MGC20579" ENSG00000184497 "Transmembrane protein 255B" Q8WV15 13 113759226-113816995 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 65.0;Endothelial cells: 81.5;granulocytes: 39.3;Hepatic stellate cells: 105.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 31.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 31.2" "Cell line enhanced" "Detected in many" "HMC-1: 28.6;HUVEC TERT2: 38.8;PC-3: 39.3;RPMI-8226: 25.1;TIME: 35.9;U-87 MG: 40.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA043334 Approved Approved Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA043334: AB_10795982" "unprognostic (2.20e-1)" "unprognostic (2.57e-3)" "unprognostic (2.05e-2)" "unprognostic (1.36e-1)" "unprognostic (4.90e-2)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "unprognostic (1.13e-1)" "unprognostic (1.99e-1)" "unprognostic (4.49e-3)" "unprognostic (3.00e-2)" "unprognostic (9.39e-2)" "prognostic unfavorable (4.12e-5)" "unprognostic (4.65e-2)" "unprognostic (1.84e-1)" "unprognostic (4.00e-1)" "unprognostic (2.83e-1)" 14.2 6.1 1.3 3.7 1.3 0.7 10.6 1.1 2.2 10.1 2.1 4.0 1.6 8.4 0.3 3.9 8.1 3.6 6.6 1.6 3.7 10.1 3.4 13.2 2.4 2.1 1.3 4.3 3.1 1.6 3.5 1.0 1.7 7.0 1.4 0.4 4.2 2.2 2.9 4.2 4.8 5.0 1.4 8.2 4.3 3.3 1.9 0.8 11.2 3.9 1.8 7.5 7.1 1.5 10.3 0.0 0.6 0.0 2.8 0.0 0.1 4.8 10.7 5.5 3.5 0.4 0.2 0.2 0.1 7.7 12.5 1.5 1.1 0.7 2.3 0.1 0.9 0.3 0.4 0.0 1.4 2.9 28.6 1.8 2.3 11.7 4.6 15.7 38.8 0.6 0.1 0.2 12.0 0.2 1.5 0.9 1.0 1.6 39.3 1.8 0.8 25.1 5.4 0.5 2.2 5.1 0.2 1.5 0.1 1.0 0.6 8.2 35.9 1.6 10.3 0.6 1.7 0.0 0.0 1.9 40.6 2.7 0.3 31.2 5.4 0.7 0.0 5.5 0.0 0.9 0.0 0.0 1.5 2.8 0.0 0.0 2.7 0.0 4.0 0.0 0.0 1.4 1.3 1.3 1.1 2.2 1.6 3.7 2.1 1.3 1.7 1.4 1.9 1.5 65.0 6.4 4.8 2.3 1.9 5.9 1.2 0.9 1.2 0.9 1.1 1.7 9.1 0.0 0.2 1.8 0.0 0.1 0.3 0.0 1.9 8.2 0.8 0.3 0.8 81.5 1.2 3.2 2.7 1.7 0.1 4.7 0.0 0.2 39.3 2.3 105.0 0.7 12.9 0.0 0.1 0.2 0.0 17.4 14.6 1.1 7.8 16.3 8.8 7.5 3.4 0.5 0.0 0.0 0.6 1.3 0.1 3.0 1.4 1.7 0.0 0.1 0.5 0.8 6.6 0.9 3.6 5.1 19.1 0.2 4.7 0.0 1.8 2.1 0.3 1.0 TMEM256 "C17orf61, MGC40107" ENSG00000205544 "Transmembrane protein 256" Q8N2U0 17 7402975-7404097 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 573.1;Proximal enterocytes: 972.0;Proximal tubular cells: 801.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062732 Approved Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA062732: AB_2684852" "unprognostic (3.82e-2)" "unprognostic (1.93e-1)" "unprognostic (2.91e-1)" "unprognostic (2.77e-2)" "unprognostic (1.05e-1)" "unprognostic (1.74e-3)" "unprognostic (3.69e-2)" "unprognostic (5.73e-2)" "unprognostic (7.45e-2)" "unprognostic (2.12e-2)" "unprognostic (3.22e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (9.36e-4)" "unprognostic (1.12e-2)" "unprognostic (1.60e-1)" "unprognostic (1.03e-1)" "unprognostic (1.19e-2)" 92.2 84.3 63.9 22.2 66.4 36.7 86.7 67.7 73.0 85.6 63.5 72.6 76.3 63.5 48.2 74.7 77.6 24.0 99.8 62.1 65.2 122.4 173.9 51.8 34.5 67.3 64.2 75.4 113.8 42.6 45.9 14.3 67.1 81.5 25.2 15.1 60.3 24.4 67.4 64.3 90.0 17.6 67.6 67.9 91.7 12.4 64.5 30.8 51.5 41.6 28.5 69.7 67.6 72.4 67.0 89.3 47.3 64.3 78.6 99.0 43.0 30.7 43.9 49.4 46.3 36.1 38.0 59.0 54.0 31.2 39.4 56.4 29.9 93.6 35.7 30.5 99.4 37.5 32.0 95.1 54.0 13.0 49.0 87.1 44.2 64.1 53.0 66.4 73.1 63.8 28.9 39.1 64.1 36.5 44.1 42.5 21.4 29.4 58.6 69.9 41.5 68.8 121.2 28.8 5.5 37.9 47.6 36.7 51.2 46.0 66.6 23.4 43.7 22.8 42.7 46.5 39.3 32.6 45.2 31.2 60.2 18.0 44.4 12.9 63.1 14.8 35.7 48.5 44.5 77.4 42.3 41.3 59.7 69.0 48.5 45.2 3.9 39.3 36.3 82.3 46.0 77.8 63.9 66.4 67.7 73.0 62.1 65.2 67.3 64.2 67.1 67.6 64.5 72.4 103.1 44.8 55.8 0.0 134.5 87.4 93.3 100.1 94.4 24.0 212.4 216.9 62.5 131.5 76.9 132.4 8.4 77.2 78.4 162.9 297.4 132.8 6.0 80.2 84.6 85.1 125.3 100.5 0.0 190.8 223.6 83.3 88.7 84.5 68.4 50.3 114.5 573.1 205.5 20.2 0.0 186.6 81.4 164.7 128.2 6.8 137.3 108.4 144.1 0.0 166.7 134.0 88.6 0.0 0.0 171.3 214.0 71.1 173.1 87.3 972.0 801.9 96.3 42.0 59.2 80.2 160.2 10.1 39.1 179.5 134.0 46.7 91.7 64.5 210.0 90.9 TMEM26 "Em:AC068892.1, MGC35010" ENSG00000196932 "Transmembrane protein 26" Q6ZUK4 10 61406642-61453381 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.8" "Cell type enhanced" "Detected in some" "Breast glandular cells: 8.2;Endometrial stromal cells: 5.4;Excitatory neurons: 5.3;Hepatic stellate cells: 4.6;Inhibitory neurons: 4.8;Kupffer cells: 12.2;Late spermatids: 5.6;Theca cells: 15.0" "Group enriched" "Detected in some" 4 "breast cancer: 2.5;endometrial cancer: 1.0;prostate cancer: 1.8;renal cancer: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 4.7;fHDF/TERT166: 1.1;HSkMC: 2.0;HUVEC TERT2: 1.5;MOLT-4: 2.3" "Region enhanced" "Detected in some" "hypothalamus: 2.3" "Low region specificity" "Detected in all" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 35: Glandular cells - Unknown function" "unprognostic (1.21e-3)" "unprognostic (2.84e-1)" "unprognostic (7.34e-2)" "unprognostic (7.83e-2)" "unprognostic (1.38e-3)" "unprognostic (1.30e-1)" "unprognostic (7.56e-2)" "unprognostic (3.69e-2)" "unprognostic (3.13e-1)" "unprognostic (9.41e-2)" "unprognostic (5.38e-2)" "unprognostic (5.24e-2)" "unprognostic (2.29e-5)" "unprognostic (2.55e-2)" "unprognostic (1.51e-2)" "unprognostic (8.53e-2)" "unprognostic (1.95e-1)" 0.5 0.5 1.3 0.9 1.4 0.1 5.2 0.3 1.1 2.3 0.2 0.7 1.4 4.0 0.1 0.5 0.4 1.0 0.2 1.1 0.8 2.2 2.5 1.4 0.7 0.8 1.0 0.5 0.0 1.4 0.2 1.5 0.4 2.6 0.9 0.0 0.0 2.4 0.8 0.0 0.8 2.0 0.5 8.8 0.2 3.6 1.5 2.1 0.4 0.2 0.2 0.7 0.5 0.7 0.0 0.0 0.1 0.0 0.1 0.8 0.1 0.0 4.7 0.4 0.6 0.0 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.0 0.0 0.5 0.0 0.5 1.5 0.5 0.0 0.0 0.1 0.0 2.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.4 0.3 1.1 1.1 0.8 0.8 1.0 0.4 0.5 1.5 0.7 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.2 2.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.8 0.7 5.4 1.7 0.0 0.0 5.3 0.0 0.0 1.4 0.0 1.6 0.0 0.1 4.6 0.2 0.3 0.0 4.8 0.0 0.0 12.2 0.0 5.6 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.2 0.0 1.7 0.0 0.0 0.0 0.1 1.2 0.5 0.2 0.0 0.1 0.0 0.1 15.0 0.0 0.0 TMEM59 "C1orf8, HSPC001" ENSG00000116209 "Transmembrane protein 59" Q9BXS4 1 54026681-54053504 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075447 Approved NA NA 27000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA075447: " "unprognostic (2.63e-1)" "unprognostic (9.88e-2)" "unprognostic (2.63e-2)" "unprognostic (2.86e-2)" "unprognostic (1.19e-1)" "unprognostic (1.41e-1)" "unprognostic (1.63e-2)" "unprognostic (8.28e-2)" "unprognostic (4.10e-1)" "unprognostic (6.57e-2)" "unprognostic (1.19e-1)" "unprognostic (4.49e-2)" "unprognostic (6.34e-3)" "unprognostic (9.84e-2)" "unprognostic (1.70e-1)" "unprognostic (6.83e-3)" "unprognostic (7.38e-2)" 257.6 359.7 181.9 164.6 220.8 259.7 341.4 240.3 253.8 343.6 379.5 488.3 364.1 208.7 415.5 241.8 403.2 299.3 275.7 178.4 202.0 473.7 505.7 264.0 162.6 240.6 205.0 225.4 586.1 532.5 170.2 325.8 239.1 350.2 485.3 254.2 550.3 279.9 194.5 194.7 369.1 219.8 235.7 188.7 433.0 174.9 204.6 186.9 341.3 247.6 189.2 289.2 202.6 286.8 188.9 122.3 142.8 185.2 844.1 371.1 182.8 347.9 499.1 211.5 276.0 99.1 391.9 96.7 322.6 595.6 257.7 281.1 166.2 237.5 221.9 237.7 177.4 133.5 266.6 166.1 317.8 165.7 268.7 408.3 411.2 207.5 219.2 566.9 246.6 127.8 158.9 326.3 245.1 91.6 97.9 137.3 201.0 528.3 226.3 94.0 251.6 403.2 257.6 248.0 208.2 173.3 381.5 386.0 398.3 266.2 184.9 348.4 259.3 259.8 90.7 193.3 187.8 289.0 338.7 114.5 349.4 275.4 222.3 1183.5 654.6 831.5 439.7 532.9 461.8 449.3 465.9 480.4 520.9 405.2 430.3 426.4 1196.5 430.4 595.9 527.1 576.1 1153.8 181.9 220.8 240.3 253.8 178.4 202.0 240.6 205.0 239.1 235.7 204.6 286.8 355.3 233.9 181.3 49.6 221.3 404.2 637.0 1214.2 237.3 150.2 409.0 325.1 155.1 479.0 991.8 437.7 118.9 477.7 244.5 905.2 160.4 527.8 357.1 348.5 201.9 279.5 408.2 277.0 44.3 352.5 528.7 410.6 226.8 217.2 155.2 89.5 334.4 413.2 320.2 132.9 42.1 672.8 1131.1 302.9 290.3 183.1 432.7 225.4 690.1 27.2 209.3 473.5 190.5 60.3 176.6 329.3 1064.8 354.0 692.8 583.2 1015.8 468.8 977.4 183.6 368.1 198.6 350.4 488.9 210.1 245.5 414.3 687.1 227.2 185.8 534.9 750.4 TMEM63C "C14orf171, CSC1, DKFZp434P0111, hsCSC1" ENSG00000165548 "Transmembrane protein 63C" Q9P1W3 14 77116568-77259495 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.7;pituitary gland: 41.9" "Cell type enhanced" "Detected in some" "Early spermatids: 9.5;Enteroendocrine cells: 19.2;Excitatory neurons: 25.8;Inhibitory neurons: 22.2;Oligodendrocyte precursor cells: 16.1" "Cancer enhanced" "Detected in many" "breast cancer: 5.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 18.5;Karpas-707: 24.1;RPMI-8226: 12.7;SCLC-21H: 32.5;SK-BR-3: 29.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030657 Uncertain Approved Centrosome NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Centrosome "HPA030657: AB_10601699" "unprognostic (2.74e-1)" "unprognostic (1.79e-2)" "unprognostic (2.30e-1)" "unprognostic (4.30e-8)" "unprognostic (2.85e-1)" "unprognostic (5.26e-2)" "unprognostic (2.68e-3)" "unprognostic (1.61e-3)" "unprognostic (2.51e-1)" "unprognostic (1.71e-1)" "unprognostic (1.21e-2)" "unprognostic (1.14e-1)" "unprognostic (2.90e-2)" "unprognostic (1.35e-3)" "unprognostic (3.72e-2)" "unprognostic (1.34e-7)" "unprognostic (5.90e-3)" 0.2 9.6 9.2 0.6 5.9 0.8 3.3 28.7 10.5 2.6 0.0 4.5 1.2 0.1 4.5 6.4 0.2 0.2 0.9 5.6 24.6 0.5 0.1 0.5 0.3 4.5 8.3 0.1 4.8 1.5 41.9 0.7 16.9 0.2 3.0 2.4 2.7 0.0 0.5 9.7 2.7 0.6 4.2 3.3 1.9 11.3 18.2 0.1 2.2 0.4 0.3 0.0 7.1 4.3 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.3 18.5 3.4 0.0 3.0 2.5 3.8 1.5 0.0 1.2 1.4 0.3 1.8 0.0 0.0 3.2 0.1 0.0 7.5 0.0 0.2 0.0 0.0 8.7 0.0 24.1 0.0 9.3 2.6 0.1 0.8 0.0 0.0 0.0 1.2 12.7 0.3 0.0 32.5 4.9 0.4 29.1 0.0 0.6 2.8 1.6 0.0 0.0 5.9 0.0 0.0 1.9 0.1 0.7 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.3 0.3 0.0 0.0 0.1 9.2 5.9 28.7 10.5 5.6 24.6 4.5 8.3 16.9 4.2 18.2 4.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.0 3.3 2.2 0.8 0.7 0.0 1.7 0.0 2.1 0.0 1.5 3.8 1.9 0.0 9.5 0.3 0.4 0.1 19.2 0.0 25.8 0.2 0.1 0.3 0.0 2.4 0.0 0.2 0.0 0.0 2.7 3.3 22.2 3.0 4.1 0.0 0.0 6.2 0.0 0.2 0.0 3.7 0.6 0.3 0.0 16.1 1.1 0.2 7.0 0.4 0.1 0.0 0.5 0.2 0.1 0.6 0.0 0.0 0.3 0.6 0.1 2.4 0.0 0.0 0.2 0.7 0.7 0.1 TMEM67 "JBTS6, MGC26979, MKS3, NPHP11" ENSG00000164953 "Transmembrane protein 67" Q5HYA8 8 93754844-93819234 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Deafness, Disease variant, Joubert syndrome, Meckel syndrome, Mental retardation, Nephronophthisis, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 66.7;Excitatory neurons: 59.8;Respiratory ciliated cells: 95.8;Rod photoreceptor cells: 83.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (1.57e-3)" "unprognostic (1.22e-1)" "unprognostic (2.45e-2)" "unprognostic (1.73e-1)" "unprognostic (5.07e-2)" "unprognostic (3.08e-1)" "unprognostic (2.25e-5)" "unprognostic (2.61e-1)" "unprognostic (1.05e-1)" "unprognostic (1.22e-2)" "unprognostic (2.51e-1)" "unprognostic (4.43e-2)" "prognostic unfavorable (7.62e-4)" "unprognostic (8.41e-2)" "unprognostic (2.21e-1)" "unprognostic (1.68e-2)" "unprognostic (2.01e-1)" 2.4 2.5 1.7 1.3 2.7 1.4 3.5 2.8 2.7 3.6 10.3 2.1 1.4 4.2 6.3 1.8 13.3 2.8 5.0 2.5 3.0 3.1 1.2 3.6 1.4 6.5 6.8 4.2 2.6 4.7 5.8 2.1 3.1 2.8 2.2 6.1 1.9 3.2 1.2 3.7 1.3 2.4 3.5 1.9 2.0 6.8 3.1 1.4 6.0 0.6 1.7 2.5 2.2 3.9 5.8 3.7 5.2 4.1 4.4 9.8 3.1 3.3 5.4 3.8 7.5 2.1 13.0 1.5 6.9 3.6 6.9 5.9 1.9 3.3 5.6 1.1 4.3 3.6 4.8 1.8 4.0 2.7 1.5 4.2 3.0 6.8 3.0 7.1 4.0 6.1 2.5 0.9 4.0 1.4 4.5 2.0 4.3 2.3 3.4 1.6 1.7 0.0 4.7 2.5 3.4 5.7 3.3 0.9 5.6 4.6 6.8 1.4 2.1 4.1 1.7 5.7 3.0 1.8 5.5 1.6 7.4 0.8 3.9 1.7 0.5 0.2 1.5 0.2 1.2 0.7 1.3 1.3 1.0 1.5 1.5 1.5 0.5 1.8 0.2 1.1 0.3 0.5 1.7 2.7 2.8 2.7 2.5 3.0 6.5 6.8 3.1 3.5 3.1 3.9 5.0 12.8 8.7 27.4 6.3 2.8 5.6 12.2 2.2 14.6 6.0 5.6 31.9 5.7 12.5 20.2 66.7 3.4 5.6 1.2 0.0 6.4 24.5 50.9 15.1 6.8 9.0 4.6 59.8 2.7 5.6 9.8 4.1 4.9 5.1 16.1 10.0 1.6 2.2 23.5 34.2 2.4 8.2 2.9 2.6 7.7 16.1 1.8 1.8 13.1 1.5 9.3 3.1 17.6 3.4 2.1 0.5 10.5 2.7 2.1 0.4 3.9 95.8 83.2 6.6 18.9 6.9 47.6 16.5 2.6 1.4 2.3 5.6 13.7 2.8 1.6 TMIGD2 "CD28H, IGPR-1, MGC23244" ENSG00000167664 "Transmembrane and immunoglobulin domain containing 2" Q96BF3 19 4292232-4302431 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 35.3" "Group enriched" "Detected in some" 4 "dendritic cells: 49.9;NK-cells: 104.0;T-cells: 45.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 114.3" "Group enriched" "Detected in many" 38 "dendritic cells: 109.4;NK-cells: 89.8;T-cells: 114.3" "Group enriched" "Detected in some" 4 "BEWO: 12.4;HEL: 30.0;MOLT-4: 27.2" "Low region specificity" "Detected in single" HPA011081 Approved NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA011081: AB_1079372" "unprognostic (1.08e-3)" "unprognostic (6.55e-2)" "unprognostic (1.89e-1)" "unprognostic (1.23e-4)" "unprognostic (4.31e-2)" "unprognostic (8.68e-3)" "unprognostic (7.78e-3)" "unprognostic (2.87e-2)" "unprognostic (1.86e-1)" "unprognostic (2.28e-1)" "unprognostic (2.12e-1)" "unprognostic (3.26e-1)" "unprognostic (7.10e-5)" "unprognostic (2.62e-2)" "unprognostic (4.54e-1)" "unprognostic (5.12e-4)" "unprognostic (8.89e-4)" 0.3 0.2 1.5 4.2 1.5 4.8 0.2 1.4 1.7 0.2 0.7 1.4 1.4 0.5 0.0 0.5 0.4 0.7 0.1 1.5 1.8 0.2 0.8 0.9 6.4 1.9 1.7 0.0 0.1 0.0 0.1 0.4 1.7 0.3 0.5 0.1 0.2 0.1 0.1 0.1 4.1 0.1 1.5 6.4 0.7 0.6 1.8 35.3 0.2 0.1 3.4 0.6 0.3 1.7 0.0 0.1 0.3 0.3 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 30.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 27.2 0.0 0.1 0.0 0.0 5.2 1.4 0.0 0.0 0.2 0.1 3.3 0.0 0.0 0.0 0.2 0.3 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.2 0.8 9.0 0.1 114.3 0.2 15.0 22.5 0.4 0.3 82.9 43.2 2.7 89.8 0.5 109.4 1.3 23.3 1.5 1.5 1.4 1.7 1.5 1.8 1.9 1.7 1.7 1.5 1.8 1.7 0.3 0.0 0.6 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.2 1.5 0.0 0.0 0.0 1.8 49.9 0.1 0.0 0.1 0.0 0.2 0.3 0.2 0.0 14.9 0.2 0.0 0.5 1.2 7.1 0.2 1.3 0.4 1.4 0.6 0.3 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 1.7 1.8 3.7 1.6 0.0 104.0 0.0 0.1 0.0 0.0 0.4 3.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 1.0 0.0 0.1 0.8 45.4 0.0 0.0 0.2 TMIGD3 AD026 ENSG00000121933 "Transmembrane and immunoglobulin domain containing 3" P0DMS9 1 111483348-111563962 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 55.1" "Cell type enhanced" "Detected in some" "Early spermatids: 272.5;Hofbauer cells: 236.3;Kupffer cells: 161.3;Late spermatids: 118.9;Spermatocytes: 198.3" "Cancer enriched" "Detected in all" 5 "glioma: 16.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 44 "eosinophil: 62.8" "Lineage enriched" "Detected in many" 44 "granulocytes: 62.8" "Cell line enhanced" "Detected in some" "HDLM-2: 7.0;HMC-1: 2.5;Karpas-707: 1.2;NB-4: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "prognostic unfavorable (3.58e-4)" "unprognostic (7.64e-3)" "unprognostic (7.47e-3)" "unprognostic (2.11e-2)" "unprognostic (6.74e-2)" "unprognostic (9.79e-2)" "unprognostic (9.48e-2)" "unprognostic (5.70e-2)" "unprognostic (1.01e-1)" "unprognostic (2.07e-3)" "unprognostic (4.46e-2)" "unprognostic (9.50e-2)" "unprognostic (4.48e-2)" "unprognostic (5.69e-3)" "unprognostic (3.30e-1)" "unprognostic (1.44e-5)" "unprognostic (9.22e-2)" 0.8 3.3 1.7 1.3 3.0 2.0 0.8 2.2 3.2 0.6 1.2 0.8 0.3 0.2 0.0 0.7 0.4 0.7 0.4 2.3 2.6 0.2 2.6 0.7 0.9 4.4 4.5 0.2 0.2 0.4 0.2 4.6 4.8 0.3 0.5 0.3 0.3 1.3 0.1 0.1 1.5 0.8 3.0 1.4 0.6 55.1 3.9 0.6 0.2 0.5 0.4 0.4 0.2 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 7.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 3.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 62.8 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.4 0.3 0.3 0.6 0.0 0.6 1.7 3.0 2.2 3.2 2.3 2.6 4.4 4.5 4.8 3.0 3.9 6.1 1.0 0.0 2.3 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 272.5 0.0 0.0 5.1 0.0 2.7 0.7 0.2 1.9 0.3 0.0 0.0 0.0 0.0 5.3 1.2 236.3 0.0 0.7 0.0 0.0 161.3 0.0 118.9 3.7 59.5 0.0 29.0 1.3 0.5 0.0 0.5 4.4 0.0 0.0 1.2 0.0 0.1 0.0 0.5 0.0 0.3 13.1 0.0 0.1 198.3 2.6 0.1 0.0 2.9 0.7 0.2 0.0 0.1 TMLHE "BBOX2, FLJ10727, TMLH, XAP130" ENSG00000185973 "Trimethyllysine hydroxylase, epsilon" Q9NVH6 X 155489011-155719098 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carnitine biosynthesis" "Dioxygenase, Oxidoreductase" "Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 51.5;Oligodendrocyte precursor cells: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034589, HPA040331" Approved Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 38: EFO-21 - Unknown function" "Cluster 68: Oligodendrocytes - Mixed function" Mitochondria "HPA034589: AB_10670571, HPA040331: AB_2676929" "unprognostic (1.98e-1)" "unprognostic (9.15e-2)" "unprognostic (3.04e-1)" "unprognostic (5.41e-2)" "unprognostic (6.66e-3)" "unprognostic (1.10e-3)" "unprognostic (6.50e-2)" "unprognostic (1.00e-1)" "unprognostic (3.27e-1)" "unprognostic (4.08e-2)" "unprognostic (1.20e-3)" "unprognostic (6.97e-2)" "prognostic favorable (3.68e-6)" "unprognostic (1.69e-1)" "unprognostic (5.74e-2)" "unprognostic (2.73e-1)" "unprognostic (7.75e-2)" 11.7 10.2 7.1 6.6 7.4 8.4 11.3 9.0 8.0 11.3 8.1 11.6 11.8 9.4 10.4 10.3 9.9 8.0 25.3 6.7 7.7 16.7 18.8 5.6 7.0 8.5 8.2 12.0 9.5 18.9 5.4 8.4 8.5 6.6 12.5 10.9 12.7 9.7 32.0 5.9 11.2 12.3 8.3 8.7 9.1 2.9 7.3 8.9 10.5 33.4 7.6 8.2 6.6 9.8 25.0 11.9 9.8 28.6 11.8 18.1 0.0 9.9 14.6 12.3 32.4 8.7 13.9 0.0 38.9 17.6 28.2 13.4 21.2 9.7 13.9 10.3 14.3 11.3 19.5 10.2 16.4 10.5 7.6 19.5 20.0 13.6 20.8 18.2 19.5 15.5 15.8 9.0 20.5 9.3 12.8 11.8 3.0 21.6 0.1 12.7 15.5 9.4 15.0 8.5 9.2 13.7 9.3 0.5 11.2 10.5 10.6 11.9 16.5 10.3 9.7 20.4 12.4 11.0 12.6 9.6 12.4 16.4 9.6 3.4 12.6 14.7 4.6 14.9 3.5 8.1 5.0 3.9 13.1 10.6 6.5 5.7 18.2 6.2 21.5 6.1 5.5 5.8 7.1 7.4 9.0 8.0 6.7 7.7 8.5 8.2 8.5 8.3 7.3 9.8 6.7 0.0 2.3 27.1 10.1 5.2 12.1 14.4 9.6 4.0 5.2 7.5 7.2 7.2 9.7 9.2 0.0 8.8 6.5 7.9 23.5 10.7 0.0 6.8 7.4 6.2 6.1 14.3 22.2 7.6 6.8 10.2 9.2 7.3 10.1 8.1 4.2 12.0 12.4 0.0 29.5 7.3 4.1 16.1 10.4 0.5 8.4 12.1 12.4 51.5 13.1 7.6 10.3 47.7 25.5 8.5 7.3 5.7 5.6 4.3 17.4 17.0 9.5 5.4 0.0 5.9 9.5 0.3 2.5 7.6 4.1 6.7 8.0 10.5 6.5 11.0 TNFAIP8L2 FLJ23467 ENSG00000163154 "TNF alpha induced protein 8 like 2" Q6P589 1 151156649-151159749 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 70.4;Kupffer cells: 65.4;Macrophages: 35.8;monocytes: 34.7;NK-cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 29.8;HL-60: 17.6;HMC-1: 44.1;NB-4: 25.2;THP-1: 95.2;U-937: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062742 Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA062742: " "unprognostic (3.19e-3)" "unprognostic (1.02e-2)" "unprognostic (6.63e-3)" "unprognostic (2.27e-2)" "unprognostic (1.29e-1)" "unprognostic (6.49e-3)" "unprognostic (1.05e-1)" "unprognostic (9.15e-3)" "prognostic favorable (3.64e-4)" "unprognostic (9.54e-2)" "unprognostic (3.32e-2)" "unprognostic (9.03e-2)" "prognostic unfavorable (3.53e-7)" "unprognostic (1.78e-1)" "unprognostic (3.91e-2)" "unprognostic (4.87e-2)" "unprognostic (2.23e-1)" 4.7 4.3 4.9 19.6 5.4 6.1 3.4 5.1 7.5 2.3 5.7 4.5 5.3 1.5 1.4 2.5 2.2 5.5 2.3 4.7 5.2 2.0 5.6 10.8 32.0 6.5 5.7 1.0 1.4 1.2 1.2 6.9 7.0 2.1 6.1 0.9 2.6 1.8 0.8 3.8 7.6 5.4 6.4 39.2 3.4 0.8 6.3 19.2 1.3 2.2 17.7 7.8 1.4 8.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 29.8 0.4 0.0 0.0 17.6 44.1 0.0 0.0 0.0 0.0 0.0 0.4 2.5 0.1 0.1 0.0 0.1 0.4 25.2 0.0 0.0 0.1 5.3 0.1 4.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 95.2 2.5 0.2 0.1 0.1 0.2 0.3 0.0 1.9 0.1 37.8 0.1 317.0 238.8 246.7 103.2 220.2 101.9 78.3 125.7 105.2 265.4 83.2 189.5 137.3 292.3 232.9 210.6 63.0 155.7 249.5 4.9 5.4 5.1 7.5 4.7 5.2 6.5 5.7 7.0 6.4 6.3 8.1 0.3 0.0 1.7 0.0 6.9 0.3 0.0 0.0 0.0 0.8 0.8 0.3 0.1 2.8 1.3 0.0 0.0 0.3 11.1 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 8.8 0.0 0.0 0.5 0.2 0.0 0.0 5.1 0.0 0.7 0.3 70.4 0.0 0.0 0.0 0.0 65.4 12.8 0.4 0.3 35.8 0.0 0.0 34.7 0.0 48.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 1.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.4 10.6 0.0 0.0 0.0 TNFRSF17 "BCM, BCMA, CD269, TNFRSF13A" ENSG00000048462 "TNF receptor superfamily member 17" Q02223 16 11965210-11968068 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 29.0;lymphoid tissue: 47.9;stomach 1: 24.4" "Cell type enriched" "Detected in some" 4 "Plasma cells: 449.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 62 "memory B-cell: 124.9;naive B-cell: 108.5;plasmacytoid DC: 103.3" "Group enriched" "Detected in many" 63 "B-cells: 124.9;dendritic cells: 103.3" "Cell line enhanced" "Detected in some" "Karpas-707: 179.6;RPMI-8226: 296.0;U-266/70: 829.4;U-266/84: 453.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA 2000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.35e-5)" "unprognostic (3.41e-2)" "unprognostic (4.00e-3)" "unprognostic (1.41e-2)" "unprognostic (6.47e-2)" "prognostic favorable (1.58e-6)" "unprognostic (9.75e-3)" "unprognostic (5.93e-2)" "unprognostic (2.13e-2)" "unprognostic (7.96e-3)" "unprognostic (2.46e-1)" "unprognostic (2.58e-1)" "unprognostic (2.85e-6)" "unprognostic (2.06e-1)" "unprognostic (2.48e-1)" "unprognostic (3.54e-2)" "unprognostic (1.10e-1)" 0.4 1.1 0.0 14.9 0.3 1.9 14.1 0.4 0.4 1.4 0.0 28.9 29.0 0.5 0.2 1.9 0.6 3.1 0.4 0.2 0.3 0.3 1.0 2.0 31.9 0.3 0.0 0.8 0.5 0.1 0.1 0.1 0.3 0.4 22.1 0.1 15.4 0.9 0.0 0.3 15.2 0.6 0.0 20.3 24.4 2.2 0.3 14.8 0.7 0.1 47.9 9.9 0.3 0.6 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.8 0.3 0.1 0.0 0.0 49.2 0.1 0.3 0.1 0.3 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 179.6 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.6 0.0 296.0 0.0 0.1 0.0 0.2 0.0 0.2 0.3 0.1 0.0 0.6 0.0 0.5 0.5 0.0 0.5 829.4 453.4 68.1 0.7 0.2 0.0 1.2 0.4 0.2 0.3 0.1 0.4 124.9 0.2 0.2 0.2 108.5 0.1 0.2 1.8 0.7 0.1 103.3 0.1 12.6 0.0 0.3 0.4 0.4 0.2 0.3 0.3 0.0 0.3 0.0 0.3 0.6 0.0 0.0 0.0 0.0 91.7 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 10.9 0.0 0.0 0.7 0.0 5.3 0.1 0.0 0.0 0.4 2.0 0.0 0.0 0.4 1.8 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 5.0 0.0 0.3 106.7 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 449.5 0.2 0.0 0.1 0.0 0.0 6.6 0.0 0.1 0.7 0.6 0.0 0.6 0.0 6.0 0.0 1.0 0.0 TNN TNW ENSG00000120332 "Tenascin N" Q9UQP3 1 175067833-175148075 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 12.0;breast: 4.9" "Cell type enhanced" "Detected in some" "Adipocytes: 6.1;Fibroblasts: 7.5;Hepatic stellate cells: 2.5;Langerhans cells: 2.5;Smooth muscle cells: 10.4" "Cancer enhanced" "Detected in some" "breast cancer: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 5.6;NB-4: 3.6;THP-1: 11.1;U-266/70: 2.7;U-937: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB010907, HPA026726, HPA026764" Uncertain "Secreted to extracellular matrix" NA NA 34000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "CAB010907: AB_477565, HPA026726: AB_10601771, HPA026764: AB_10601859" "unprognostic (1.16e-3)" "unprognostic (2.23e-2)" "unprognostic (1.35e-1)" "unprognostic (2.21e-2)" "unprognostic (1.34e-1)" "unprognostic (1.48e-1)" "unprognostic (1.48e-1)" "unprognostic (3.55e-1)" "unprognostic (5.25e-3)" "unprognostic (1.01e-2)" "unprognostic (4.69e-1)" "unprognostic (5.07e-1)" "unprognostic (1.08e-3)" "unprognostic (1.76e-2)" "unprognostic (9.38e-3)" "unprognostic (1.89e-2)" "unprognostic (1.02e-2)" 12.0 0.2 0.0 0.1 0.1 0.0 4.9 0.0 0.1 0.1 0.1 0.3 0.8 0.0 0.0 0.1 0.0 1.7 0.3 0.2 0.0 0.4 1.3 0.4 0.1 0.0 0.1 0.0 0.3 0.8 2.0 0.1 0.0 0.0 0.1 0.0 3.2 0.0 0.0 3.1 0.4 0.4 0.1 0.4 0.4 0.1 0.1 0.1 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 11.1 0.0 0.0 0.0 0.0 0.0 2.7 0.4 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.1 6.1 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.7 0.0 0.1 7.5 0.0 0.1 0.0 0.0 2.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 2.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 10.4 0.4 1.4 0.0 1.8 0.1 0.1 0.0 0.0 0.1 TOM1L1 SRCASM ENSG00000141198 "Target of myb1 like 1 membrane trafficking protein" O75674 17 54899387-54961956 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 103.7;Late spermatids: 184.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022916 Uncertain NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" "HPA022916: AB_1858181" "unprognostic (1.50e-1)" "unprognostic (7.70e-3)" "prognostic favorable (1.61e-4)" "unprognostic (9.59e-2)" "unprognostic (1.59e-3)" "unprognostic (6.26e-3)" "unprognostic (1.18e-2)" "unprognostic (1.32e-1)" "unprognostic (2.49e-3)" "unprognostic (2.00e-2)" "unprognostic (2.14e-1)" "unprognostic (3.87e-2)" "prognostic favorable (3.81e-6)" "unprognostic (7.47e-2)" "unprognostic (1.12e-1)" "unprognostic (1.24e-1)" "unprognostic (3.62e-2)" 7.8 16.5 5.7 7.1 6.8 1.4 32.9 7.7 6.9 36.5 19.8 33.6 106.9 12.6 45.1 21.1 35.0 19.0 8.0 4.9 6.2 78.7 108.2 17.1 5.2 4.8 5.9 4.8 42.4 64.9 12.9 6.8 4.1 32.9 36.4 19.1 32.8 20.1 2.7 20.6 60.9 8.5 6.4 4.2 54.7 15.4 6.2 7.9 57.5 3.4 12.0 12.1 12.1 6.0 48.6 50.3 8.8 59.6 0.2 0.5 0.6 25.2 39.9 24.0 33.8 33.1 48.3 0.2 62.2 22.7 36.5 31.4 47.9 52.6 36.0 1.2 59.7 72.3 43.5 52.4 50.2 0.4 0.2 21.3 83.8 22.5 124.2 44.0 14.5 14.3 30.9 0.4 23.7 45.1 2.1 0.7 21.1 90.1 36.1 0.6 39.2 29.2 108.5 61.2 42.2 48.5 24.8 41.5 60.1 41.9 102.7 7.0 17.8 13.3 1.9 31.7 45.3 0.9 37.1 1.1 22.4 0.2 28.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.1 5.7 6.8 7.7 6.9 4.9 6.2 4.8 5.9 4.1 6.4 6.2 6.0 1.1 22.4 21.6 15.3 1.9 15.8 17.2 21.3 19.4 14.3 30.4 26.7 4.9 27.1 20.6 36.8 22.9 8.9 0.8 37.4 103.7 60.8 82.5 29.4 6.0 0.9 18.7 3.8 57.0 44.9 3.7 4.2 36.7 29.7 1.3 16.4 1.8 43.2 3.1 15.2 28.6 55.2 8.2 1.3 1.2 184.0 2.8 3.1 12.4 7.5 3.2 12.7 0.0 40.7 20.2 52.0 30.4 3.0 0.7 26.0 86.1 93.2 20.1 19.0 6.6 4.9 6.5 2.5 6.6 28.0 17.8 3.1 1.2 21.5 42.8 18.5 TPD52L1 "D53, hD53, TPD53" ENSG00000111907 "TPD52 like 1" Q16890 6 125119049-125264407 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 258.3;salivary gland: 298.3" "Cell type enhanced" "Detected in many" "Astrocytes: 390.1;Squamous epithelial cells: 272.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 269.1;hTCEpi: 234.3;MCF7: 365.5;RPTEC TERT1: 271.4;SK-BR-3: 189.4;T-47d: 162.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027915, HPA027916" Enhanced Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cell Junctions, Cytosol" "HPA027915: AB_10602074, HPA027916: AB_10601860" "unprognostic (1.44e-1)" "unprognostic (2.01e-2)" "unprognostic (2.76e-2)" "unprognostic (1.26e-1)" "unprognostic (1.39e-1)" "unprognostic (2.87e-2)" "unprognostic (1.38e-2)" "unprognostic (2.14e-1)" "unprognostic (7.85e-2)" "unprognostic (7.80e-2)" "unprognostic (9.42e-3)" "unprognostic (1.76e-1)" "prognostic favorable (3.26e-4)" "unprognostic (1.06e-1)" "unprognostic (6.83e-2)" "prognostic favorable (3.97e-4)" "prognostic unfavorable (5.34e-4)" 44.7 258.3 83.9 10.1 96.2 0.8 67.0 72.6 97.4 35.8 103.4 36.2 9.7 15.2 68.8 152.4 34.6 27.3 71.4 78.4 81.3 40.6 58.4 10.9 6.6 81.4 76.8 20.7 47.1 67.3 24.8 8.9 78.8 41.0 13.0 1.9 298.3 79.1 111.9 47.9 10.6 12.3 68.5 2.0 43.1 5.1 81.5 3.4 60.7 126.2 12.3 59.6 60.8 76.6 37.7 42.0 0.5 269.1 2.4 0.6 63.3 6.2 5.9 0.0 0.7 67.3 46.9 0.1 136.2 31.2 9.1 83.8 8.4 58.2 0.2 0.8 58.0 0.8 58.0 0.5 5.7 0.2 0.1 7.4 234.3 0.1 30.7 82.5 0.0 0.0 30.5 0.6 4.7 365.5 0.0 0.7 4.4 36.8 22.7 0.4 0.1 0.0 271.4 9.8 9.1 0.2 70.5 189.4 4.6 9.6 162.3 0.8 0.2 1.8 5.9 0.5 2.0 0.1 0.1 0.2 1.0 0.3 0.7 1.8 0.5 0.3 0.3 0.2 0.3 0.3 0.6 0.2 0.2 0.4 0.7 0.5 2.7 2.6 0.1 0.4 0.2 0.4 83.9 96.2 72.6 97.4 78.4 81.3 81.4 76.8 78.8 68.5 81.5 76.6 141.6 0.0 28.3 390.1 2.2 19.6 44.6 70.2 128.1 3.8 164.4 154.9 45.8 25.8 51.7 125.0 4.2 32.7 3.2 3.9 176.1 30.7 6.9 71.7 21.1 87.2 16.2 0.0 16.4 110.8 140.2 18.8 13.7 184.5 2.5 29.5 15.4 59.9 10.9 0.0 48.2 11.3 83.4 2.1 5.2 4.9 17.4 3.4 131.6 28.1 0.6 3.9 1.0 11.6 2.9 35.3 2.3 36.5 2.6 37.1 10.9 45.4 15.7 1.3 0.0 177.1 10.1 5.7 9.2 272.2 37.2 14.4 3.5 53.8 17.8 19.2 TPPP2 "C14orf8, CT152, p18, p25beta" ENSG00000179636 "Tubulin polymerization promoting protein family member 2" P59282 14 21024109-21036276 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "testis: 254.8" "Cell type enriched" "Detected in some" 4 "Late spermatids: 9161.6" "Cancer enhanced" "Detected in single" "liver cancer: 0.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA004120 Enhanced NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "HPA004120: AB_2303582" "unprognostic (2.91e-2)" "unprognostic (2.49e-3)" "unprognostic (2.54e-1)" "unprognostic (1.66e-2)" "unprognostic (2.14e-2)" "unprognostic (2.57e-3)" "unprognostic (4.63e-4)" "unprognostic (3.83e-1)" "unprognostic (3.16e-1)" "unprognostic (1.09e-1)" "unprognostic (4.64e-4)" "unprognostic (2.51e-4)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (3.21e-1)" 0.1 0.4 0.8 0.1 0.9 0.0 0.5 0.8 1.1 0.2 1.3 0.1 0.1 0.2 3.4 0.0 0.2 0.3 0.6 0.8 0.8 0.9 13.3 0.1 0.0 0.9 0.8 0.8 0.2 0.2 0.1 0.0 0.9 0.4 0.3 0.3 1.4 0.2 3.2 0.1 0.3 0.0 0.9 0.1 0.1 254.8 0.9 0.0 0.1 4.7 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.8 1.1 0.8 0.8 0.9 0.8 0.9 0.9 0.9 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.3 1.9 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.1 1897.4 0.1 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 5.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 9161.6 47.5 2.7 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 35.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 52.0 30.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 TPST2 TANGO13B ENSG00000128294 "Tyrosylprotein sulfotransferase 2" O60704 22 26521996-26596717 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 398.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 171.0;NK-cells: 263.7;Plasma cells: 183.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 158.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021054 Enhanced "Intracellular and membrane" NA NA 88000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA021054: AB_1858221" "unprognostic (2.24e-1)" "unprognostic (1.70e-1)" "unprognostic (1.74e-2)" "prognostic favorable (8.08e-5)" "unprognostic (8.88e-2)" "unprognostic (1.06e-1)" "unprognostic (1.19e-2)" "unprognostic (9.70e-2)" "unprognostic (3.18e-2)" "unprognostic (3.38e-1)" "unprognostic (2.70e-1)" "unprognostic (5.54e-2)" "prognostic unfavorable (2.34e-6)" "unprognostic (9.68e-2)" "unprognostic (9.21e-3)" "unprognostic (5.62e-2)" "unprognostic (2.01e-1)" 24.4 31.0 24.4 15.2 20.8 23.1 21.8 19.1 29.9 17.4 26.9 11.5 13.6 18.0 111.6 18.7 17.0 12.2 27.5 23.4 22.9 24.9 74.9 45.7 19.1 22.0 24.2 9.2 398.8 5.3 9.9 41.8 20.8 16.0 8.8 3.3 10.9 17.8 38.5 18.4 13.4 12.1 23.1 36.4 11.7 20.6 34.2 10.7 38.8 22.6 17.0 17.1 17.3 20.7 12.8 9.1 11.7 6.0 24.4 18.7 16.4 27.9 49.9 22.2 20.3 6.2 6.5 21.4 7.3 50.4 11.6 19.5 8.8 19.2 12.7 8.8 16.9 51.8 5.6 13.1 10.2 6.0 158.7 20.1 30.3 22.5 7.7 22.5 41.6 9.6 52.6 65.2 17.2 14.3 24.3 40.7 15.4 10.0 9.1 22.5 15.8 60.2 6.7 14.3 8.8 6.1 12.9 11.2 16.0 17.0 5.2 24.7 33.2 27.3 61.2 22.5 27.3 20.9 31.5 20.6 20.7 23.1 25.3 490.4 77.0 111.9 249.2 86.3 70.5 23.6 57.0 187.2 48.3 25.6 27.8 163.6 163.0 354.9 94.3 115.3 71.9 240.7 24.4 20.8 19.1 29.9 23.4 22.9 22.0 24.2 20.8 23.1 34.2 20.7 37.3 16.0 12.6 13.7 30.8 38.1 82.5 29.9 14.2 9.0 10.8 13.1 15.5 47.1 14.4 22.0 6.2 171.0 120.8 6.7 27.4 12.9 15.2 31.1 14.8 66.1 0.0 64.6 23.4 65.1 49.8 10.7 5.1 39.5 53.7 13.9 113.6 79.3 123.9 6.7 20.3 9.3 12.2 55.9 48.6 4.5 5.3 70.1 28.4 47.8 32.4 1.9 263.7 5.0 1.9 53.1 8.7 4.1 183.7 36.4 16.5 7.6 18.6 5.3 6.6 9.9 15.3 2.9 13.2 15.1 35.9 143.0 64.4 42.0 11.8 83.7 TRAPPC8 "GSG1, HsT2706, KIAA1012, TRS85" ENSG00000153339 "Trafficking protein particle complex 8" Q9Y2L5 18 31829197-31953136 "Predicted intracellular proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 8.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041107 Approved Approved Microtubules,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol Microtubules "HPA041107: AB_10793869" "unprognostic (4.04e-1)" "unprognostic (4.35e-2)" "unprognostic (2.62e-3)" "unprognostic (9.80e-2)" "unprognostic (8.18e-2)" "unprognostic (4.06e-2)" "unprognostic (9.68e-2)" "unprognostic (1.37e-1)" "unprognostic (7.67e-3)" "unprognostic (4.42e-2)" "unprognostic (3.00e-1)" "unprognostic (6.35e-3)" "prognostic favorable (1.85e-9)" "unprognostic (3.55e-2)" "unprognostic (7.03e-2)" "unprognostic (4.26e-1)" "unprognostic (2.92e-1)" 10.5 9.9 5.4 10.1 6.1 10.2 9.8 8.5 6.7 9.3 11.3 9.9 10.2 8.5 5.9 11.5 9.6 7.6 10.5 5.8 5.6 12.7 18.1 8.9 13.0 6.3 5.2 9.0 9.8 14.6 7.1 9.7 5.8 8.3 10.9 20.9 10.4 8.7 16.9 13.6 11.9 9.4 5.0 10.7 10.0 30.2 5.5 16.3 12.4 12.4 13.4 9.2 9.7 8.7 12.3 10.2 11.9 9.0 17.3 16.3 13.0 16.0 16.9 14.7 14.4 7.0 9.1 17.6 12.6 15.5 13.4 18.4 17.2 9.1 20.2 19.8 8.0 14.4 9.5 8.7 13.5 42.4 16.1 14.9 12.1 13.8 19.6 16.4 17.0 14.6 21.2 15.7 15.0 8.4 18.2 14.5 11.9 36.1 8.7 19.0 14.1 18.5 14.4 19.1 9.0 10.6 20.5 12.2 14.3 18.7 13.5 18.3 20.8 15.5 7.8 5.7 9.9 19.6 23.5 25.9 15.0 18.2 16.3 8.7 1.6 1.7 1.0 1.5 2.2 1.3 1.4 1.2 1.6 1.4 1.2 1.3 2.3 1.9 1.5 1.2 1.7 0.7 5.4 6.1 8.5 6.7 5.8 5.6 6.3 5.2 5.8 5.0 5.5 8.7 16.9 28.9 15.1 44.1 26.3 18.0 8.7 10.0 31.9 12.2 14.3 9.7 21.6 21.5 14.6 11.0 29.2 11.2 19.9 27.3 1.9 11.0 35.3 23.4 14.9 16.1 12.6 20.0 68.1 9.4 9.6 14.8 32.6 17.4 3.8 11.1 19.6 34.2 16.6 11.8 71.6 14.7 8.2 24.0 13.3 42.4 15.5 22.3 10.6 43.1 23.4 11.0 23.7 55.3 82.8 14.2 10.1 9.4 18.7 16.1 26.2 15.5 25.8 24.7 13.1 14.8 14.3 88.8 47.4 21.8 27.1 20.5 16.6 11.6 13.7 15.5 TRAT1 "HSPC062, TCRIM, TRIM" ENSG00000163519 "T cell receptor associated transmembrane adaptor 1" Q6PIZ9 3 108822770-108855005 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "lymphoid tissue: 79.8" "Cell type enriched" "Detected in some" 10 "T-cells: 129.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 395.1" "Group enriched" "Detected in many" 155 "granulocytes: 395.1;T-cells: 313.1" "Group enriched" "Detected in some" 25 "JURKAT: 29.9;MOLT-4: 76.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA002356, CAB026130, HPA072760" Enhanced Enhanced "Plasma membrane,Mitotic spindle,Centriolar satellite" Yes NA "Cluster 32: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Mitotic spindle, Centriolar satellite" "CAB026130: , HPA002356: AB_1080375, HPA072760: " "unprognostic (1.54e-4)" "unprognostic (1.41e-3)" "unprognostic (6.82e-2)" "unprognostic (4.95e-3)" "unprognostic (2.84e-2)" "unprognostic (2.19e-3)" "unprognostic (1.87e-3)" "unprognostic (2.02e-2)" "unprognostic (7.21e-3)" "unprognostic (8.96e-3)" "unprognostic (8.03e-2)" "unprognostic (4.32e-1)" "unprognostic (2.86e-5)" "unprognostic (3.12e-1)" "unprognostic (3.01e-2)" "unprognostic (2.90e-4)" "unprognostic (4.36e-2)" 1.1 0.6 0.0 11.0 0.0 2.7 0.8 0.0 0.0 0.4 0.0 1.3 1.4 0.4 0.4 1.0 0.3 2.5 0.4 0.1 0.0 0.3 1.3 2.1 23.9 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.8 1.5 0.0 0.6 0.1 0.1 0.6 3.0 0.5 0.0 8.5 2.4 0.4 0.0 79.8 0.4 0.4 12.4 2.9 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.9 0.0 2.1 0.0 0.0 76.0 0.0 0.0 0.0 0.0 0.6 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 395.1 0.6 0.2 57.0 0.2 116.4 1.0 229.5 119.6 0.3 0.4 313.1 77.7 3.5 2.2 0.7 0.8 111.1 139.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 3.2 0.0 3.3 8.4 0.1 0.0 0.0 0.0 0.4 0.3 0.3 0.0 0.0 1.8 0.0 0.0 8.9 0.1 0.0 0.0 2.3 0.1 0.1 1.1 0.0 2.7 0.1 0.0 0.0 1.7 7.7 0.1 2.5 0.0 1.8 0.6 0.2 0.0 0.2 0.0 0.0 1.0 12.2 2.2 0.0 1.8 3.6 0.0 3.2 0.0 3.1 0.0 0.2 0.0 0.0 0.0 5.1 0.2 0.0 0.5 0.0 0.0 0.0 0.3 0.8 0.0 0.1 0.0 8.0 0.1 129.3 0.6 0.0 0.2 TRBC1 "BV05S1J2.2, TCRBC1" ENSG00000211751 "T cell receptor beta constant 1" 7 142791694-142793368 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 28 "lymphoid tissue: 1520.1" "Group enriched" "Detected in many" 10 "dendritic cells: 338.0;NK-cells: 580.9;T-cells: 399.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 3232.4" "Lineage enriched" "Detected in all" 9 "T-cells: 3232.4" "Cell line enriched" "Detected in some" 5 "JURKAT: 1467.5" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (1.08e-4)" "unprognostic (7.96e-4)" "unprognostic (6.02e-2)" "unprognostic (1.26e-4)" "unprognostic (1.81e-2)" "unprognostic (5.42e-5)" "unprognostic (1.76e-2)" "unprognostic (6.94e-3)" "unprognostic (2.36e-3)" "unprognostic (1.29e-2)" "unprognostic (1.67e-2)" "unprognostic (3.56e-1)" "unprognostic (3.18e-6)" "unprognostic (3.98e-1)" "unprognostic (8.83e-3)" "unprognostic (1.02e-1)" "unprognostic (4.19e-3)" 9.2 5.1 1.3 140.0 1.5 53.5 9.5 1.1 2.1 7.7 1.5 18.5 26.8 6.4 5.7 12.0 7.0 26.7 5.0 1.0 1.1 5.4 11.4 31.5 322.2 2.0 1.2 6.4 2.7 0.9 2.0 2.3 1.7 9.0 19.4 0.0 19.0 4.6 1.0 9.9 49.7 4.2 1.7 92.5 27.1 2.7 1.6 1520.1 8.4 2.1 227.0 33.2 6.2 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.6 0.0 1467.5 2.0 0.0 0.0 0.0 0.0 1.7 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.3 296.5 2.0 0.0 1.9 0.0 45.6 7.2 4.7 869.6 3.5 693.8 17.1 1893.1 1259.3 5.8 15.7 1989.8 1450.7 37.3 359.8 8.3 9.7 3232.4 1917.5 1.3 1.5 1.1 2.1 1.0 1.1 2.0 1.2 1.7 1.7 1.6 1.9 7.3 19.2 40.8 0.0 11.7 0.0 0.3 0.0 0.0 0.0 5.9 5.5 0.0 0.0 3.1 1.8 0.0 0.2 338.0 0.0 0.0 0.5 0.6 1.1 0.7 1.5 0.0 10.7 0.0 0.0 0.1 3.2 4.6 0.8 20.2 0.0 5.3 1.5 0.3 0.0 0.0 0.1 0.0 8.4 0.0 1.9 17.4 13.9 0.0 0.0 17.3 0.0 580.9 0.0 0.0 0.0 0.1 8.2 23.6 0.3 0.0 2.4 0.7 0.0 0.0 1.1 3.5 0.0 0.1 0.5 0.0 0.1 399.0 0.1 0.1 0.4 TRBV27 "TCRBV14S1, TCRBV27S1" ENSG00000211752 "T cell receptor beta variable 27" A0A0K0K1C4 7 142715346-142715861 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 81.6" "Cell type enriched" "Detected in some" 4 "T-cells: 6.1" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "memory CD4 T-cell: 61.1;memory CD8 T-cell: 112.2;naive CD4 T-cell: 48.2;naive CD8 T-cell: 75.8;T-reg: 94.7" "Lineage enriched" "Detected in single" 137 "T-cells: 112.2" "Group enriched" "Detected in some" 4 "HAP1: 2.9;JURKAT: 3.3;U-937: 3.6" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (3.08e-2)" "unprognostic (2.10e-2)" "unprognostic (5.66e-2)" "unprognostic (5.85e-4)" "unprognostic (8.84e-2)" "unprognostic (7.89e-2)" "unprognostic (1.91e-2)" "unprognostic (1.28e-4)" "unprognostic (1.49e-1)" "unprognostic (4.36e-2)" "unprognostic (1.91e-7)" "unprognostic (4.03e-1)" "unprognostic (3.91e-2)" "unprognostic (8.10e-2)" "unprognostic (6.43e-2)" 0.6 0.5 0.0 3.5 0.6 1.9 0.8 0.0 0.3 0.7 0.0 1.2 1.0 0.9 0.1 0.8 0.2 1.8 0.2 0.0 0.0 0.4 0.5 1.7 19.7 0.0 0.3 0.5 0.2 0.0 0.1 0.1 0.0 0.5 1.7 0.0 1.7 0.0 0.3 0.2 2.8 0.2 0.0 4.8 1.9 5.7 0.2 81.6 0.6 0.8 10.6 1.6 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.4 0.1 0.6 3.3 0.0 10.4 0.1 61.1 112.2 0.1 0.1 48.2 75.8 0.8 0.1 0.2 0.1 94.7 27.3 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 TRGC2 "TCRGC2, TRGC2(2X), TRGC2(3X)" ENSG00000227191 "T cell receptor gamma constant 2" 7 38239580-38249572 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "bone marrow: 30.5;lymphoid tissue: 34.6;prostate: 23.7" "Group enriched" "Detected in some" 7 "dendritic cells: 149.1;NK-cells: 90.6;T-cells: 122.0" "Cancer enriched" "Detected in many" 18 "prostate cancer: 26.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 720.5" "Lineage enriched" "Detected in many" 5 "T-cells: 720.5" "Cell line enhanced" "Detected in some" "HL-60: 11.4;JURKAT: 36.6;NB-4: 29.9;SK-BR-3: 9.8;U-937: 53.9" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (2.79e-3)" "prognostic favorable (1.06e-5)" "unprognostic (1.62e-4)" "unprognostic (3.52e-5)" "unprognostic (3.34e-1)" "unprognostic (1.46e-3)" "unprognostic (8.79e-4)" "unprognostic (4.60e-2)" "unprognostic (1.10e-2)" "unprognostic (1.91e-3)" "unprognostic (1.12e-1)" "unprognostic (3.90e-1)" "unprognostic (2.48e-2)" "unprognostic (1.98e-1)" "unprognostic (2.92e-1)" "unprognostic (1.77e-1)" "unprognostic (5.91e-3)" 3.6 1.1 8.8 5.1 9.0 30.5 1.8 8.6 19.6 1.5 7.1 3.5 4.5 1.3 3.2 1.1 2.2 3.9 0.9 8.4 8.5 1.6 3.6 9.7 17.5 9.6 8.9 0.5 0.8 0.2 1.0 0.5 9.2 23.7 4.0 0.1 1.8 0.8 0.4 0.6 8.0 1.0 9.3 29.7 3.8 2.2 10.2 34.6 2.1 0.1 7.0 3.4 2.3 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 11.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 36.6 0.0 0.0 0.0 3.7 1.2 29.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 53.9 0.0 1.1 1.3 1.4 720.5 1.2 287.4 0.6 64.8 341.6 1.0 0.3 13.5 212.9 4.9 149.7 1.0 1.2 1.3 167.5 8.8 9.0 8.6 19.6 8.4 8.5 9.6 8.9 9.2 9.3 10.2 9.5 1.2 0.0 2.4 0.0 2.4 0.0 0.2 0.0 0.0 0.0 1.0 1.3 0.7 1.5 0.6 0.0 0.0 0.0 149.1 0.3 0.0 0.2 15.5 0.2 0.1 0.8 0.0 6.6 0.0 0.0 0.0 0.4 2.6 0.2 0.0 0.2 3.9 1.0 0.0 0.0 0.0 0.5 0.0 3.5 0.0 6.7 0.0 2.8 0.0 0.0 10.6 0.0 90.6 0.0 0.0 0.0 0.0 0.4 14.2 2.8 0.0 0.5 0.0 0.0 0.0 0.2 1.3 0.8 0.2 0.3 0.0 0.3 122.0 0.0 0.2 0.3 TRGV9 "TCRGV9, V2" ENSG00000211695 "T cell receptor gamma variable 9" Q99603 7 38317017-38318861 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 1.9;prostate: 5.5" "Group enriched" "Detected in some" 4 "dendritic cells: 14.6;NK-cells: 22.6;T-cells: 37.7" "Cancer enriched" "Detected in single" 126 "prostate cancer: 13.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 13 "gdT-cell: 426.5" "Lineage enriched" "Detected in many" 13 "T-cells: 426.5" "Group enriched" "Detected in some" 6 "MCF7: 7.7;NB-4: 2.4;U-937: 8.6" "Not detected" "Not detected" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 19: Lung - Lung function" "Cluster 32: U-937 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.07e-1)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "unprognostic (3.98e-3)" "unprognostic (4.43e-2)" "unprognostic (4.13e-2)" "unprognostic (1.29e-2)" "unprognostic (2.06e-1)" "unprognostic (1.83e-1)" "unprognostic (1.47e-1)" "unprognostic (1.51e-3)" "unprognostic (2.41e-1)" "unprognostic (6.60e-4)" "unprognostic (1.29e-1)" "unprognostic (4.95e-1)" 0.4 0.0 0.4 0.5 0.7 1.1 0.1 0.4 0.5 0.1 0.2 0.2 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.5 0.5 0.0 0.2 0.4 0.5 0.7 0.5 0.0 0.1 0.0 0.0 1.9 0.7 5.5 0.2 0.8 0.1 0.0 0.0 0.0 0.2 0.0 0.4 1.6 0.3 0.1 0.5 1.5 0.0 0.0 0.4 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 7.7 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.6 0.0 0.0 0.3 0.1 426.5 0.6 29.0 0.1 1.6 19.7 0.4 0.0 0.7 8.4 1.4 33.2 0.1 0.5 0.1 38.8 0.4 0.7 0.4 0.5 0.5 0.5 0.7 0.5 0.7 0.4 0.5 0.8 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 4.6 0.0 0.0 0.1 1.1 0.1 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 22.6 0.0 0.0 0.0 0.0 0.0 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.7 0.0 0.0 0.0 TRIB2 "GS3955, TRB2" ENSG00000071575 "Tribbles pseudokinase 2" Q92519 2 12716889-12742734 "Enzymes, Predicted membrane proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 104.3;Muller glia cells: 100.3" "Cancer enhanced" "Detected in all" "melanoma: 74.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 48.8" "Group enriched" "Detected in many" 8 "B-cells: 12.2;NK-cells: 19.3;T-cells: 48.8" "Cell line enhanced" "Detected in many" "AN3-CA: 183.5;HEL: 185.7;K-562: 258.0;SK-MEL-30: 189.3;WM-115: 246.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001305 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 34: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm Cytosol "HPA001305: AB_1080371" "unprognostic (1.84e-1)" "unprognostic (2.49e-2)" "unprognostic (4.31e-3)" "unprognostic (1.86e-3)" "unprognostic (6.68e-3)" "unprognostic (3.93e-2)" "unprognostic (4.10e-1)" "unprognostic (1.53e-1)" "unprognostic (2.80e-2)" "unprognostic (3.32e-2)" "unprognostic (2.52e-3)" "unprognostic (1.67e-2)" "unprognostic (1.08e-3)" "unprognostic (1.30e-1)" "unprognostic (8.71e-2)" "unprognostic (9.59e-2)" "unprognostic (2.13e-2)" 43.3 63.1 29.1 38.9 29.9 16.8 38.3 36.1 35.2 21.7 30.5 27.0 17.8 44.4 43.4 15.5 23.4 28.8 51.0 31.6 37.7 92.3 21.0 39.8 72.7 31.4 30.8 97.8 26.2 18.0 20.0 46.6 29.7 33.0 13.4 137.8 20.4 25.6 14.3 16.9 25.2 34.2 29.7 79.7 41.8 28.5 32.4 39.3 23.9 19.5 69.6 48.4 19.5 28.0 0.2 0.4 138.8 183.5 48.9 44.7 0.2 7.9 7.5 4.9 7.9 0.9 15.3 16.3 5.5 16.9 0.8 2.3 10.3 16.1 4.2 18.3 28.9 185.7 0.4 2.7 60.7 10.7 68.0 41.7 16.0 20.3 5.6 48.9 22.1 23.8 258.0 0.3 7.9 1.7 24.4 44.8 66.1 7.0 18.0 0.0 46.2 6.7 31.9 23.4 118.9 56.6 1.1 7.4 189.3 41.4 0.2 1.1 13.9 65.3 32.0 0.6 17.8 0.1 0.2 22.9 35.2 36.3 246.7 1.7 0.2 3.2 12.7 0.0 15.8 9.6 26.1 13.8 1.2 12.2 15.0 9.2 0.5 19.3 0.2 0.1 48.8 8.9 29.1 29.9 36.1 35.2 31.6 37.7 31.4 30.8 29.7 29.7 32.4 28.0 52.2 3.2 8.3 25.5 12.5 6.1 9.1 26.9 19.4 55.0 7.9 8.6 17.1 12.8 15.6 16.5 31.3 2.6 17.5 0.7 7.9 17.2 4.3 9.7 11.6 43.9 0.0 22.1 13.5 104.3 0.2 11.3 20.9 15.9 34.2 77.3 59.6 6.7 5.8 20.2 6.9 0.4 28.5 5.1 8.2 14.3 77.3 3.8 30.2 13.1 3.0 100.3 26.8 59.8 2.7 45.3 0.2 74.4 21.0 11.6 0.3 1.0 17.9 66.7 52.6 9.9 41.2 1.0 6.0 5.7 5.4 0.8 27.1 30.5 0.8 32.5 TRIP10 "CIP4, HSTP, STOT, STP" ENSG00000125733 "Thyroid hormone receptor interactor 10" Q15642 19 6737925-6751530 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 362.8" "Cell type enhanced" "Detected in many" "monocytes: 196.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 26.4" "Lineage enriched" "Detected in many" 10 "dendritic cells: 26.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041934, HPA072625, HPA073886" Approved Supported Nucleoplasm,Vesicles NA NA 24000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 59: Non-specific - Translation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 3: Monocytes - Immune response regulation" Vesicles Nucleoplasm "HPA041934: AB_2677754, HPA072625: AB_2732206, HPA073886: AB_2732244" "unprognostic (5.75e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (3.61e-4)" "unprognostic (2.19e-2)" "unprognostic (6.57e-2)" "prognostic favorable (1.76e-4)" "unprognostic (6.73e-3)" "unprognostic (1.10e-3)" "unprognostic (1.51e-1)" "unprognostic (3.41e-1)" "unprognostic (7.87e-3)" "unprognostic (3.28e-1)" "prognostic unfavorable (4.66e-4)" "unprognostic (1.14e-2)" "unprognostic (1.42e-1)" "unprognostic (8.93e-2)" "unprognostic (8.83e-2)" 110.7 60.3 15.5 25.5 15.6 8.6 92.3 15.3 17.8 123.9 18.6 112.1 30.5 66.5 17.5 253.3 80.1 27.6 125.7 14.6 16.7 81.7 27.0 115.4 14.5 17.5 16.5 99.4 44.7 18.6 22.4 48.6 16.0 80.4 19.9 16.9 85.4 45.0 362.8 57.8 56.0 26.4 15.8 40.0 58.6 29.9 17.5 9.6 75.5 177.3 21.9 86.7 147.4 14.8 83.5 49.7 17.1 25.8 64.7 67.9 61.1 52.5 60.0 58.8 51.1 67.8 46.7 1.8 69.2 44.6 47.6 60.2 38.8 76.5 34.7 52.5 15.5 27.0 48.4 52.3 53.4 1.4 8.3 79.0 50.9 52.5 39.8 77.2 61.2 3.7 40.2 22.1 43.7 28.3 7.5 18.7 36.3 51.9 41.7 12.2 35.1 24.5 50.0 40.9 0.1 19.6 69.1 30.7 20.0 39.4 32.2 14.7 120.5 39.3 70.4 103.8 56.4 23.1 13.4 8.4 63.6 7.9 26.2 0.0 0.8 0.0 0.6 0.1 0.9 1.5 0.3 1.1 5.2 1.7 0.3 0.2 0.1 2.5 0.1 26.4 0.0 0.5 15.5 15.6 15.3 17.8 14.6 16.7 17.5 16.5 16.0 15.8 17.5 14.8 43.0 28.9 19.8 6.5 5.6 85.4 104.9 76.9 43.9 14.7 28.3 16.6 8.7 20.0 66.9 16.5 37.5 9.9 16.5 39.1 5.9 45.0 16.4 30.3 32.1 43.1 7.7 4.4 0.1 38.0 37.9 66.3 10.7 55.7 29.7 8.8 38.9 3.7 9.6 0.0 0.2 16.3 24.4 6.7 90.4 13.6 55.9 19.6 37.4 3.7 196.9 12.5 0.0 5.5 0.4 91.5 24.7 36.1 9.0 116.6 25.8 23.8 24.8 18.5 32.9 26.4 46.4 5.7 6.9 51.3 83.3 14.2 7.4 24.5 25.9 120.7 TRIQK "C8orf83, DKFZp779L1068, LOC286144, PRO0845" ENSG00000205133 "Triple QxxK/R motif containing" Q629K1 8 92883532-93017673 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 32.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.47e-3)" "unprognostic (3.09e-1)" "unprognostic (6.03e-3)" "unprognostic (4.32e-2)" "unprognostic (1.47e-1)" "unprognostic (1.21e-1)" "unprognostic (5.13e-2)" "unprognostic (7.78e-2)" "unprognostic (2.50e-1)" "unprognostic (2.31e-1)" "unprognostic (1.56e-1)" "unprognostic (2.52e-1)" "unprognostic (1.79e-1)" "unprognostic (5.11e-3)" "unprognostic (9.23e-2)" "unprognostic (7.15e-2)" "unprognostic (2.79e-2)" 12.8 21.9 12.3 7.7 15.7 14.5 14.5 18.6 14.9 19.4 10.5 20.7 12.4 12.5 9.7 9.8 15.7 22.9 20.1 13.7 13.5 19.4 31.3 17.0 5.3 13.4 12.6 19.6 18.0 20.6 10.7 19.6 14.0 18.1 21.0 12.4 11.1 10.2 2.4 5.7 12.1 11.4 14.2 13.2 17.5 6.5 13.5 7.3 23.4 5.6 5.2 15.5 7.9 17.0 7.4 9.2 19.8 7.0 27.1 42.8 6.6 26.4 28.4 14.7 20.9 1.3 22.9 0.0 31.6 24.9 9.8 11.9 16.1 15.9 23.7 0.0 7.6 28.9 10.1 15.6 22.9 8.1 24.0 32.0 35.4 8.0 27.1 33.3 15.7 16.3 5.6 16.7 21.3 19.7 13.1 6.3 6.8 31.3 33.8 0.0 20.5 9.6 27.8 9.1 11.4 16.0 10.0 3.9 25.6 16.3 27.2 7.1 20.5 21.8 6.7 38.3 8.3 5.8 0.0 0.0 33.8 0.1 22.5 0.9 17.0 15.9 0.1 18.8 8.1 2.8 0.9 0.7 9.4 1.9 0.0 0.0 14.6 2.0 32.9 2.5 0.2 4.7 12.3 15.7 18.6 14.9 13.7 13.5 13.4 12.6 14.0 14.2 13.5 17.0 19.0 19.2 17.9 21.9 4.0 15.0 21.4 17.1 22.8 18.9 17.7 12.4 13.8 25.8 14.1 16.5 6.2 7.3 2.1 16.2 50.9 14.8 7.0 21.3 27.7 17.8 19.2 6.7 36.8 16.4 23.8 23.5 20.9 24.5 2.5 11.7 17.2 18.3 11.9 6.7 43.6 35.6 12.2 20.0 13.6 8.0 16.4 18.5 23.2 31.9 24.3 22.8 3.1 34.7 56.3 12.5 14.0 21.8 1.0 22.2 17.0 39.1 29.5 6.3 32.9 18.4 18.2 12.1 5.3 12.3 8.4 3.7 3.3 21.6 20.0 22.6 TRPC1 HTRP-1 ENSG00000144935 "Transient receptor potential cation channel subfamily C member 1" P48995 3 142724034-142807888 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Astrocytes: 93.7;Excitatory neurons: 144.6;Granulosa cells: 91.8;Inhibitory neurons: 184.4;Microglial cells: 49.6;Oligodendrocyte precursor cells: 154.8;Oligodendrocytes: 164.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 23.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009387, HPA021130" Supported Approved Vesicles NA NA "Cluster 21: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Vesicles "CAB009387: AB_2240941, HPA021130: AB_1858361" "unprognostic (1.66e-1)" "unprognostic (7.38e-2)" "unprognostic (1.56e-2)" "unprognostic (4.37e-5)" "unprognostic (5.53e-1)" "unprognostic (1.40e-2)" "unprognostic (5.90e-3)" "unprognostic (1.59e-2)" "unprognostic (1.36e-1)" "unprognostic (2.17e-1)" "unprognostic (8.46e-3)" "unprognostic (6.25e-2)" "prognostic unfavorable (2.72e-5)" "unprognostic (1.44e-3)" "unprognostic (1.57e-1)" "unprognostic (1.61e-1)" "unprognostic (2.49e-2)" 5.2 4.7 7.3 1.9 7.9 0.3 4.7 10.9 7.5 9.1 5.8 7.6 1.2 11.1 5.2 3.6 8.6 5.4 10.1 7.9 7.0 3.2 0.8 3.3 1.9 7.1 5.6 14.2 1.4 6.5 10.3 3.5 7.7 7.0 2.5 22.8 2.9 7.8 1.2 3.6 3.9 10.6 6.1 2.8 3.2 4.8 6.1 1.5 5.1 3.6 1.0 6.3 6.9 7.9 4.2 5.7 10.8 1.2 9.7 23.9 4.8 6.8 10.5 8.4 12.2 1.7 1.1 0.0 2.1 7.0 14.2 0.3 3.0 3.2 12.2 1.0 4.1 6.8 2.6 2.9 4.0 0.4 0.0 11.4 3.2 7.9 9.4 14.2 4.9 0.0 0.2 0.0 12.1 2.6 0.4 0.5 6.0 0.1 3.1 0.0 5.0 0.0 5.9 0.1 6.7 4.8 8.1 0.0 1.5 9.9 3.3 0.1 4.3 10.1 1.6 14.0 9.1 3.9 1.8 2.1 7.7 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 7.3 7.9 10.9 7.5 7.9 7.0 7.1 5.6 7.7 6.1 6.1 7.9 6.2 3.2 0.5 93.7 2.9 2.9 1.6 1.2 7.4 17.9 0.9 1.8 12.0 1.5 0.6 5.5 16.7 0.2 0.3 0.0 0.0 0.3 3.6 0.5 10.8 4.6 1.8 0.4 144.6 0.2 0.2 13.2 0.0 0.9 0.0 91.8 3.6 0.0 0.1 13.5 184.4 0.0 0.0 0.0 1.6 2.9 8.4 0.5 1.8 49.6 0.1 7.7 0.0 154.8 164.8 0.1 0.0 10.9 1.5 0.9 0.0 0.7 3.0 16.0 0.0 10.4 12.0 9.8 2.8 0.7 1.1 0.3 2.2 1.7 0.0 0.3 TRPC5 PPP1R159 ENSG00000072315 "Transient receptor potential cation channel subfamily C member 5" Q9UL62 X 111768011-112082776 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "brain: 3.7" "Group enriched" "Detected in some" 11 "Excitatory neurons: 46.3;Inhibitory neurons: 78.5;Oligodendrocytes: 38.3" "Group enriched" "Detected in some" 23 "testis cancer: 0.8;thyroid cancer: 2.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "NTERA-2: 1.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (3.29e-2)" "unprognostic (6.15e-2)" "unprognostic (7.32e-2)" "unprognostic (2.60e-3)" "unprognostic (3.68e-2)" "unprognostic (5.69e-2)" "unprognostic (5.09e-2)" "unprognostic (2.78e-2)" 0.0 0.1 0.6 0.0 2.7 0.1 0.0 0.9 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.1 0.0 0.8 0.0 0.0 1.9 3.7 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.7 0.9 1.7 1.3 2.1 1.9 3.7 2.2 0.3 0.6 0.8 0.0 0.0 0.0 4.9 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 78.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.5 38.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 TRUB2 CLONE24922 ENSG00000167112 "TruB pseudouridine synthase family member 2" O95900 9 128305159-128322447 "Predicted intracellular proteins" "mRNA processing" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021211 Uncertain NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA021211: AB_1858375" "unprognostic (2.40e-1)" "unprognostic (2.02e-2)" "unprognostic (1.31e-1)" "unprognostic (3.72e-2)" "unprognostic (7.38e-2)" "unprognostic (2.47e-1)" "unprognostic (1.13e-1)" "unprognostic (4.52e-2)" "unprognostic (1.22e-1)" "unprognostic (7.49e-2)" "unprognostic (3.04e-2)" "unprognostic (4.81e-3)" "prognostic favorable (5.57e-10)" "unprognostic (8.74e-3)" "unprognostic (8.81e-2)" "unprognostic (1.75e-1)" "unprognostic (1.08e-1)" 3.7 8.5 8.7 3.6 9.0 4.2 4.7 8.9 9.3 3.3 8.7 4.5 5.0 3.3 2.9 6.3 4.1 2.7 8.7 8.5 8.1 6.5 12.9 2.4 4.5 9.3 9.3 3.8 5.2 7.2 6.8 2.7 9.8 3.6 4.2 3.6 4.8 3.4 7.2 5.4 4.3 3.2 7.7 3.6 4.6 3.1 9.5 3.5 4.7 9.8 4.3 4.0 3.5 9.9 6.6 14.9 6.7 9.2 10.7 7.9 7.1 7.1 8.5 11.6 9.5 11.1 8.3 14.7 6.0 9.7 11.0 17.5 15.4 12.4 7.8 7.1 10.2 6.9 12.8 10.4 8.2 12.7 8.9 10.0 13.7 11.4 10.7 7.2 12.0 12.8 26.2 6.4 9.3 19.7 17.1 14.7 9.2 22.2 19.0 13.3 10.9 21.0 10.7 5.9 14.4 10.6 13.2 14.6 9.5 5.2 19.1 8.7 8.1 9.4 7.5 11.2 8.6 7.5 16.4 11.9 9.9 9.9 10.5 3.6 3.6 1.1 5.0 3.8 5.7 6.3 4.8 5.7 5.5 5.3 5.5 5.7 1.8 6.5 2.0 3.8 6.2 3.8 8.7 9.0 8.9 9.3 8.5 8.1 9.3 9.3 9.8 7.7 9.5 9.9 10.9 25.6 10.3 1.6 17.1 9.6 13.7 43.0 15.4 21.3 14.6 15.7 49.9 24.3 27.0 35.0 16.7 51.6 10.9 19.8 64.6 39.0 12.9 15.1 20.7 16.4 19.1 16.2 5.0 35.4 45.9 15.4 27.0 15.9 8.2 22.0 17.2 50.7 31.0 3.3 5.2 26.4 34.6 9.0 4.1 16.4 20.8 12.4 12.4 3.7 16.8 15.4 18.6 3.0 10.5 27.2 19.1 18.0 17.8 14.9 34.0 78.6 16.9 16.7 0.0 17.2 16.3 15.8 19.2 22.1 10.5 28.0 13.9 46.1 35.3 11.1 TSPAN18 TSPAN ENSG00000157570 "Tetraspanin 18" Q96SJ8 11 44726465-44932423 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 83.5" "Group enriched" "Detected in many" 6 "Adipocytes: 72.2;Cardiomyocytes: 22.3;Early spermatids: 29.7;Endothelial cells: 51.8;Hepatic stellate cells: 70.3;Proximal tubular cells: 20.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 36.7;CAPAN-2: 61.5;GAMG: 35.2;HDLM-2: 48.7;NTERA-2: 33.0;RH-30: 38.4;SCLC-21H: 31.9;SH-SY5Y: 36.2;SuSa: 99.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.09e-1)" "unprognostic (1.97e-1)" "unprognostic (8.53e-3)" "unprognostic (3.48e-2)" "unprognostic (6.30e-2)" "unprognostic (8.64e-2)" "unprognostic (7.17e-2)" "unprognostic (2.91e-2)" "unprognostic (8.75e-2)" "unprognostic (1.07e-1)" "unprognostic (1.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.04e-3)" "unprognostic (6.78e-3)" "unprognostic (3.22e-1)" "unprognostic (2.19e-1)" "unprognostic (5.59e-2)" 22.2 46.1 5.8 10.4 4.3 1.2 10.0 30.5 8.2 14.4 3.6 47.9 6.7 46.7 3.6 21.0 20.8 13.3 83.5 26.1 4.6 14.5 4.9 22.4 7.7 5.1 10.4 7.4 1.6 3.9 5.4 30.2 4.9 15.8 9.9 1.0 3.3 41.4 14.7 6.3 16.4 46.6 8.9 14.1 16.6 4.0 10.8 4.0 14.8 19.9 4.2 23.1 10.2 2.3 0.0 0.6 36.7 0.5 0.0 0.0 0.0 0.6 0.5 2.3 0.1 7.3 61.5 0.0 16.4 1.0 35.2 0.0 6.6 0.2 0.6 48.7 2.4 0.2 5.0 0.0 0.0 0.2 0.1 0.7 0.0 0.1 0.0 0.0 14.3 0.2 1.1 0.0 0.1 0.0 0.0 0.1 33.0 0.1 1.0 0.1 38.4 0.2 0.0 0.0 31.9 36.2 0.4 0.1 0.1 99.8 0.2 0.1 1.4 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 1.6 1.0 0.0 0.0 1.6 0.1 0.0 0.8 0.2 1.1 0.5 0.0 0.0 1.3 0.2 0.3 0.5 0.0 0.0 0.3 1.7 5.8 4.3 30.5 8.2 26.1 4.6 5.1 10.4 4.9 8.9 10.8 2.3 72.2 0.0 3.7 5.5 1.5 1.7 0.1 0.0 0.6 1.8 1.0 0.3 22.3 0.0 0.0 7.3 0.0 0.1 1.1 0.0 0.0 0.4 29.7 0.7 0.9 51.8 0.0 3.6 2.7 0.2 0.2 6.8 0.5 1.4 1.3 0.0 70.3 1.0 0.4 1.7 4.1 0.0 0.0 2.5 2.6 5.6 2.8 3.4 7.2 2.8 0.2 0.1 0.0 4.0 1.3 0.7 0.0 1.5 0.6 0.2 0.0 20.2 0.0 0.5 0.0 4.9 2.0 0.6 1.0 0.0 1.1 0.3 3.0 3.2 0.0 0.1 TSPAN7 "A15, CD231, DXS1692E, MRX58, MXS1, TALLA-1, TM4SF2" ENSG00000156298 "Tetraspanin 7" P41732 X 38561542-38688920 "CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 542.1" "Cell type enhanced" "Detected in many" "Astrocytes: 274.9;Excitatory neurons: 215.6;Hepatic stellate cells: 407.3;Inhibitory neurons: 249.8;Oligodendrocyte precursor cells: 353.4" "Cancer enhanced" "Detected in all" "glioma: 71.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 109.5;JURKAT: 380.9;MOLT-4: 239.7;SCLC-21H: 129.0;U-266/70: 163.2" "Low region specificity" "Detected in all" "HPA003140, CAB062566, CAB068245" Enhanced NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB062566: AB_2665608, CAB068245: AB_2665609, HPA003140: AB_1078454" "unprognostic (1.12e-2)" "unprognostic (1.42e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.40e-4)" "unprognostic (5.06e-2)" "unprognostic (3.90e-3)" "unprognostic (3.88e-3)" "unprognostic (1.37e-2)" "unprognostic (1.14e-1)" "unprognostic (2.01e-2)" "prognostic favorable (1.70e-4)" "unprognostic (1.54e-1)" "prognostic favorable (5.48e-7)" "unprognostic (5.65e-3)" "unprognostic (9.53e-2)" "unprognostic (1.48e-1)" "unprognostic (1.03e-3)" 56.1 125.6 355.5 17.2 433.8 1.3 33.5 369.5 542.1 42.6 271.3 68.1 36.3 43.8 37.6 33.6 36.5 25.8 70.3 413.7 334.3 56.2 45.0 67.4 41.1 290.3 298.8 19.6 19.8 13.9 28.0 25.1 283.6 18.8 64.6 286.9 12.5 26.8 153.9 19.4 34.0 51.1 291.7 96.3 14.5 4.8 331.7 15.7 51.3 232.3 28.9 29.7 16.9 384.6 0.1 0.0 2.9 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 3.8 1.6 0.0 109.5 14.9 0.5 0.0 67.2 0.0 0.1 1.2 1.5 0.0 0.0 0.0 0.0 0.0 380.9 0.0 0.4 1.7 0.4 239.7 0.0 11.2 0.1 0.0 14.6 4.6 0.0 11.0 1.4 129.0 14.4 0.0 0.0 4.3 6.5 0.0 0.3 0.0 0.1 3.1 0.1 1.0 163.2 54.8 0.0 5.4 0.4 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 355.5 433.8 369.5 542.1 413.7 334.3 290.3 298.8 283.6 291.7 331.7 384.6 116.1 12.8 23.8 274.9 1.1 10.6 2.7 6.3 6.2 92.0 1.0 3.8 34.1 1.5 4.6 11.0 43.8 0.4 0.2 69.1 23.5 0.4 0.0 2.1 1.6 153.3 18.7 5.3 215.6 0.6 0.4 14.0 4.6 5.6 10.1 108.1 407.3 4.8 45.1 97.6 249.8 23.5 0.0 15.0 10.0 1.9 0.6 1.5 14.2 46.9 0.0 102.3 0.0 353.4 50.6 0.9 21.9 3.0 1.5 2.4 40.3 9.8 1.2 107.4 59.2 26.5 11.7 0.6 3.3 9.9 6.5 0.8 2.6 27.0 35.7 0.9 TST RDS ENSG00000128311 "Thiosulfate sulfurtransferase" Q16762 22 37010859-37020183 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 561.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 565.8;Hepatocytes: 414.9;Paneth cells: 463.4;Proximal enterocytes: 278.5;Proximal tubular cells: 254.5;Undifferentiated cells: 217.4" "Cancer enhanced" "Detected in all" "liver cancer: 177.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.0" "Group enriched" "Detected in all" 6 "dendritic cells: 25.0;granulocytes: 21.8;monocytes: 17.7" "Cell line enhanced" "Detected in many" "OE19: 264.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003044, HPA003643, CAB009546" Enhanced Supported Mitochondria NA NA 560000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "CAB009546: AB_2211220, HPA003044: AB_1858417, HPA003643: AB_1080411" "unprognostic (3.09e-2)" "unprognostic (2.70e-1)" "unprognostic (2.07e-1)" "unprognostic (1.21e-2)" "unprognostic (2.36e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-2)" "unprognostic (2.38e-2)" "unprognostic (2.32e-1)" "unprognostic (7.96e-3)" "unprognostic (4.38e-2)" "unprognostic (1.78e-1)" "prognostic favorable (7.59e-6)" "unprognostic (6.08e-3)" "unprognostic (3.46e-1)" "unprognostic (1.16e-1)" "prognostic favorable (1.04e-4)" 51.4 154.1 31.3 20.9 40.5 27.1 37.3 38.2 36.0 34.1 31.3 190.7 147.7 18.9 2.9 96.7 25.7 75.9 69.9 29.1 33.1 100.8 561.2 22.7 8.1 34.4 35.2 26.9 63.6 9.4 12.4 7.9 34.4 26.4 80.3 1.3 39.8 18.2 52.9 33.8 114.2 13.2 35.4 16.9 88.4 8.1 35.8 4.3 17.1 34.9 16.2 30.0 56.7 39.0 42.6 86.1 10.8 36.8 25.9 10.6 21.4 23.0 18.6 12.6 18.3 25.4 25.7 11.1 18.8 17.0 11.9 35.1 7.9 22.3 2.7 33.6 50.0 11.5 15.5 49.7 64.9 16.4 26.4 20.1 23.9 9.1 7.6 17.5 31.1 5.9 14.2 18.2 6.0 90.8 0.5 49.9 18.7 264.4 39.3 37.0 11.7 19.7 35.9 36.7 6.4 17.1 24.2 41.4 31.7 10.2 43.4 39.3 25.1 14.0 27.2 24.2 7.4 14.0 15.4 3.4 5.3 46.4 8.5 10.9 17.7 8.0 0.8 4.7 1.7 2.8 0.8 0.6 25.0 1.7 0.4 0.2 21.8 3.7 1.5 1.7 2.1 8.1 31.3 40.5 38.2 36.0 29.1 33.1 34.4 35.2 34.4 35.4 35.8 39.0 13.9 28.9 74.8 10.1 7.8 1.3 9.5 20.4 12.0 1.3 32.7 16.6 39.2 170.1 23.7 20.2 0.0 11.6 2.5 565.8 46.9 45.3 1.9 53.3 30.2 13.4 34.3 35.3 0.3 44.0 6.4 14.6 126.9 74.3 14.0 60.9 39.3 414.9 15.1 1.7 0.5 162.8 8.2 28.9 6.8 3.5 13.1 23.2 1.8 1.0 18.6 27.3 3.1 3.5 7.4 36.8 463.4 7.9 24.5 10.5 278.5 254.5 19.2 0.8 0.0 10.7 11.5 2.4 0.5 39.8 2.4 11.4 5.0 57.5 217.4 17.3 TTC16 FLJ32780 ENSG00000167094 "Tetratricopeptide repeat domain 16" Q8NEE8 9 127716079-127731590 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "fallopian tube: 6.9;testis: 16.0" "Group enriched" "Detected in some" 4 "Early spermatids: 103.1;Late spermatids: 258.3" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.6;naive CD8 T-cell: 1.5" "Lineage enriched" "Detected in single" 16 "T-cells: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (3.10e-3)" "unprognostic (1.63e-3)" "unprognostic (3.86e-3)" "unprognostic (2.02e-4)" "unprognostic (4.08e-3)" "unprognostic (2.25e-3)" "unprognostic (8.87e-4)" "unprognostic (2.91e-2)" "unprognostic (2.25e-2)" "unprognostic (2.36e-1)" "unprognostic (1.96e-3)" "unprognostic (7.32e-2)" "unprognostic (9.14e-3)" "unprognostic (6.35e-3)" "unprognostic (5.29e-2)" "unprognostic (1.17e-1)" "unprognostic (5.54e-3)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.2 0.0 6.9 0.1 0.0 0.1 0.1 0.1 0.0 0.7 0.4 0.3 0.6 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 16.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 1.0 0.0 0.5 1.1 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.6 0.2 0.2 0.1 0.1 0.1 0.0 0.6 0.0 0.4 0.1 0.1 1.0 0.0 0.0 0.2 0.1 0.8 1.5 5.7 0.0 0.0 0.0 13.7 0.0 0.0 0.0 103.1 6.0 0.1 0.5 1.2 0.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 2.0 0.3 0.0 258.3 1.2 0.3 1.8 0.0 0.3 0.2 9.2 4.5 0.1 0.0 0.0 3.8 2.6 0.0 0.0 0.4 41.8 0.5 0.0 0.1 0.4 17.9 1.6 0.0 0.0 0.0 7.4 3.8 0.0 0.1 TTPA AVED ENSG00000137561 "Alpha tocopherol transfer protein" P49638 8 63048553-63086053 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "liver: 165.0" "Group enriched" "Detected in some" 4 "Astrocytes: 37.9;Hepatocytes: 72.0" "Cancer enriched" "Detected in some" 9 "liver cancer: 21.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 2.0;SK-BR-3: 6.0;T-47d: 2.1;U-2 OS: 2.9;U-2197: 3.7" "Low region specificity" "Detected in all" NA NA 10000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.48e-1)" "unprognostic (3.42e-1)" "unprognostic (7.82e-3)" "unprognostic (1.30e-7)" "unprognostic (1.78e-1)" "unprognostic (8.44e-2)" "unprognostic (1.25e-2)" "unprognostic (7.84e-2)" "unprognostic (4.04e-2)" "unprognostic (3.50e-1)" "unprognostic (5.40e-2)" "unprognostic (3.28e-1)" "unprognostic (1.14e-2)" "unprognostic (1.49e-2)" "unprognostic (3.57e-2)" "unprognostic (5.46e-3)" "unprognostic (6.16e-3)" 1.6 0.2 2.7 0.4 2.7 0.2 0.5 3.0 2.3 0.1 0.7 3.1 0.3 0.0 0.0 0.1 0.1 0.3 0.0 2.5 2.5 2.4 165.0 0.7 0.2 2.5 3.2 0.0 1.2 3.6 0.1 1.7 2.4 0.1 4.3 0.9 0.1 0.1 0.2 0.2 0.3 0.2 2.1 0.0 0.3 0.3 3.0 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.8 0.5 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.4 0.0 0.0 0.0 2.0 0.0 1.5 0.1 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.7 0.0 0.1 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.5 6.0 0.6 0.0 2.1 0.2 0.1 0.0 2.9 3.7 0.6 0.2 0.0 0.0 1.3 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.7 2.7 3.0 2.3 2.5 2.5 2.5 3.2 2.4 2.1 3.0 2.3 0.0 3.2 1.1 37.9 0.2 0.0 0.0 0.0 0.0 0.1 0.6 0.4 0.1 7.2 1.3 0.0 0.0 11.2 0.0 2.1 1.9 1.1 0.0 0.0 0.1 0.2 2.4 0.0 1.0 0.2 0.0 0.3 0.0 0.0 0.0 0.3 1.8 72.0 0.6 0.0 2.7 2.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 12.9 0.0 10.6 0.1 0.1 1.2 0.0 0.0 0.1 0.0 5.5 0.0 0.2 0.0 0.7 0.1 0.0 1.0 0.0 0.1 9.9 0.1 0.0 4.9 0.1 TUFM "EF-TuMT, EFTu" ENSG00000178952 "Tu translation elongation factor, mitochondrial" P49411 16 28842411-28846348 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Elongation factor" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018991, HPA024087, CAB075730, CAB075731, CAB075732" Enhanced Enhanced Mitochondria NA NA 610000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB075730: AB_2665736, CAB075731: AB_2665737, CAB075732: AB_2665738, HPA018991: AB_1858458, HPA024087: AB_1858459" "unprognostic (1.40e-1)" "unprognostic (7.56e-2)" "unprognostic (1.29e-1)" "unprognostic (1.73e-2)" "unprognostic (2.36e-1)" "unprognostic (2.55e-2)" "unprognostic (3.39e-1)" "unprognostic (1.23e-3)" "unprognostic (8.05e-2)" "unprognostic (8.47e-2)" "unprognostic (1.80e-1)" "unprognostic (1.33e-1)" "prognostic favorable (2.69e-6)" "unprognostic (5.26e-2)" "unprognostic (1.09e-1)" "unprognostic (6.22e-2)" "unprognostic (7.36e-2)" 69.7 114.6 69.6 67.1 74.2 75.1 65.8 78.9 78.1 59.4 93.3 101.5 104.4 64.9 34.7 105.2 73.6 46.6 177.8 68.1 75.3 107.3 145.1 58.3 69.2 73.1 77.4 61.4 114.2 117.1 55.4 47.6 74.1 57.7 86.1 35.8 88.9 59.7 224.4 76.0 83.9 53.6 72.9 66.2 106.1 73.3 77.0 59.9 62.7 221.5 79.3 67.1 62.9 74.3 176.2 323.1 102.4 216.2 144.9 131.4 208.7 125.8 144.4 194.9 183.0 351.3 189.4 390.5 228.5 126.4 112.4 337.6 244.2 242.9 116.2 155.4 370.8 151.7 254.8 433.6 171.7 273.8 134.8 169.9 188.1 211.9 208.7 126.8 235.2 213.0 339.0 150.3 144.4 355.0 262.3 266.3 231.8 213.9 196.9 361.8 187.3 569.6 169.3 168.4 178.8 219.6 110.0 388.5 180.2 84.6 231.5 217.6 150.1 115.9 136.4 146.7 196.6 229.8 253.6 172.2 148.6 336.8 157.1 94.6 155.8 72.3 103.1 153.6 115.3 100.6 97.2 108.7 199.3 98.8 91.7 95.3 32.4 97.2 119.2 123.1 140.1 185.6 69.6 74.2 78.9 78.1 68.1 75.3 73.1 77.4 74.1 72.9 77.0 74.3 108.2 70.5 76.7 29.4 144.6 168.1 262.5 322.0 158.2 102.4 165.1 139.2 134.4 190.1 182.6 176.6 87.6 333.1 113.2 260.0 334.6 230.2 381.8 116.1 92.5 111.3 148.5 148.1 17.5 289.8 299.2 111.2 153.4 79.6 105.9 170.6 108.5 247.1 253.8 74.0 19.9 230.5 217.7 167.5 146.4 669.0 109.3 128.6 138.7 14.0 167.5 140.6 88.6 28.6 30.3 199.7 215.3 111.7 264.9 245.3 330.7 451.9 237.3 116.3 85.5 105.5 129.1 205.7 177.4 230.1 156.0 287.0 120.2 288.2 418.7 277.6 TULP3 TUBL3 ENSG00000078246 "TUB like protein 3" O75386 12 2877223-2941138 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015285, HPA018496" Uncertain Supported "Nucleoplasm,Nucleoli,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nucleoli" "Plasma membrane" "HPA015285: AB_1858460, HPA018496: AB_2669889" "unprognostic (5.33e-2)" "unprognostic (1.57e-1)" "unprognostic (4.80e-2)" "prognostic favorable (2.99e-4)" "unprognostic (2.45e-1)" "unprognostic (1.78e-2)" "prognostic unfavorable (7.97e-5)" "unprognostic (2.44e-1)" "unprognostic (4.09e-2)" "unprognostic (1.73e-1)" "unprognostic (1.50e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (7.18e-4)" "unprognostic (7.52e-2)" "unprognostic (1.94e-1)" "unprognostic (2.36e-2)" "unprognostic (3.19e-2)" 21.0 17.1 13.6 7.5 14.2 2.6 18.3 19.2 16.1 33.3 15.8 21.6 5.4 23.2 11.7 17.8 24.3 12.1 17.7 13.8 13.2 17.3 9.0 13.5 6.1 16.3 14.8 37.7 9.6 13.3 12.3 13.7 13.8 15.4 8.2 12.7 13.0 13.9 10.4 25.7 10.5 18.2 14.5 9.4 15.5 13.0 14.4 9.4 15.5 9.7 8.1 16.7 24.1 17.1 22.6 18.8 35.0 29.1 34.3 51.0 32.9 34.5 57.5 36.4 40.2 24.0 20.4 16.7 5.1 51.2 31.2 18.5 21.1 22.2 42.0 21.7 15.4 10.0 23.4 15.5 44.3 10.8 11.1 30.1 25.7 55.3 74.9 44.6 28.6 20.8 9.7 15.1 31.0 20.3 16.1 9.4 47.4 17.8 13.7 16.8 34.2 6.3 22.9 18.7 8.8 23.4 30.1 17.8 19.9 63.4 22.2 10.5 23.0 26.6 32.0 54.7 33.9 4.7 6.0 14.3 26.9 5.9 41.5 0.0 0.9 0.3 2.1 0.8 3.5 1.6 1.7 2.2 0.7 1.8 2.0 2.8 0.4 2.7 0.5 1.6 3.3 1.0 13.6 14.2 19.2 16.1 13.8 13.2 16.3 14.8 13.8 14.5 14.4 17.1 12.9 6.4 10.5 70.5 6.2 20.3 16.9 14.8 26.2 6.1 9.9 12.2 8.0 18.6 15.9 1.8 2.1 9.4 6.0 4.6 23.5 17.3 5.8 35.1 33.5 15.2 3.6 6.1 6.0 7.3 10.6 31.7 6.6 14.6 0.0 11.5 24.3 5.5 5.3 40.4 10.8 4.0 14.2 2.5 8.6 3.6 40.7 5.4 19.6 14.0 6.7 50.7 12.3 10.1 34.9 11.1 2.4 24.8 8.3 23.3 3.2 21.9 47.4 10.0 39.5 22.3 26.3 38.0 50.8 22.2 20.2 11.6 6.5 13.3 6.4 13.2 TXNRD2 "SELZ, TR, TR3, TRXR2" ENSG00000184470 "Thioredoxin reductase 2" Q9NNW7 22 19875517-19941820 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2 OS: 139.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002007, HPA003323" Supported Approved Mitochondria,Cytosol NA NA 2800000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 47: Cytotrophoblasts - Unknown function" "Mitochondria, Cytosol" "CAB002007: , HPA003323: AB_1080396" "unprognostic (3.17e-2)" "unprognostic (8.72e-2)" "unprognostic (4.30e-1)" "unprognostic (9.71e-3)" "unprognostic (7.25e-2)" "unprognostic (6.35e-2)" "unprognostic (3.21e-1)" "unprognostic (1.12e-1)" "unprognostic (2.78e-1)" "unprognostic (2.83e-1)" "unprognostic (4.94e-3)" "unprognostic (2.49e-1)" "prognostic favorable (1.10e-7)" "unprognostic (2.47e-1)" "unprognostic (5.99e-2)" "unprognostic (1.69e-1)" "unprognostic (1.10e-1)" 10.5 44.4 11.9 8.9 12.0 14.5 12.3 18.1 19.3 11.7 21.2 14.9 10.3 10.6 6.2 10.2 10.6 6.2 30.0 12.9 11.9 24.8 65.4 13.6 9.1 11.8 12.1 16.5 15.9 13.5 14.4 9.8 11.5 26.8 4.6 4.4 15.4 8.2 23.0 10.9 12.0 5.1 11.3 16.9 26.4 14.6 12.4 4.9 15.2 16.1 6.1 11.8 10.4 11.8 19.4 39.2 3.5 14.9 6.9 9.6 8.8 18.8 21.1 31.8 23.4 36.7 19.4 10.9 43.2 19.0 32.7 33.2 17.8 25.2 12.1 21.6 46.5 18.8 34.4 22.4 12.9 21.1 8.4 9.2 18.5 16.2 13.8 12.9 91.3 2.2 106.4 17.4 24.8 47.1 7.2 30.1 17.7 46.9 27.6 10.5 85.2 10.0 19.3 21.0 19.1 16.4 32.0 39.9 21.8 5.8 33.7 27.6 52.2 23.0 139.5 19.8 38.4 17.6 14.0 6.9 22.4 15.5 30.3 2.7 10.5 5.8 3.5 8.2 2.6 3.9 3.0 3.2 7.8 2.6 3.9 3.2 0.9 3.8 7.9 2.9 2.1 4.6 11.9 12.0 18.1 19.3 12.9 11.9 11.8 12.1 11.5 11.3 12.4 11.8 5.6 16.0 23.6 11.1 10.3 4.2 23.1 15.1 3.4 22.1 11.4 9.1 16.7 15.7 15.7 20.2 10.4 60.7 8.8 14.7 58.7 22.0 26.4 9.8 8.4 14.4 1.2 33.1 9.2 32.0 24.3 12.4 23.4 10.0 1.3 27.6 8.9 49.5 25.9 10.1 8.5 16.9 20.3 22.0 7.8 18.2 15.5 14.6 5.4 10.3 27.2 18.7 10.3 8.5 7.2 22.3 13.9 9.1 12.2 17.8 15.6 52.0 16.6 11.0 6.6 11.3 13.3 10.9 14.0 6.4 5.3 42.0 11.4 36.4 16.4 15.7 TXNRD3 "TGR, TR2, TR2IT1, TRXR3, TXNRD3IT1, TXNRD3NB, TXNRD3NT1" ENSG00000197763 "Thioredoxin reductase 3" Q86VQ6 3 126571779-126655124 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Electron transport, Spermatogenesis, Transport" "Developmental protein, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 20.4" "Cell type enhanced" "Detected in many" "Spermatocytes: 71.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020802, HPA036109" Uncertain Enhanced Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm Cytosol "CAB020802: , HPA036109: AB_2674945" "unprognostic (1.41e-1)" "unprognostic (1.55e-2)" "unprognostic (3.92e-1)" "prognostic unfavorable (3.35e-4)" "unprognostic (3.90e-1)" "unprognostic (2.96e-1)" "unprognostic (3.01e-1)" "unprognostic (3.39e-2)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (2.86e-4)" "unprognostic (3.14e-1)" "prognostic favorable (2.72e-4)" "unprognostic (5.94e-2)" "unprognostic (1.74e-1)" "unprognostic (1.03e-2)" "unprognostic (2.51e-1)" 4.9 4.0 2.4 2.2 2.4 1.1 6.1 3.4 1.9 4.7 3.1 2.4 1.3 5.1 5.9 4.8 3.6 3.6 3.1 1.8 3.3 5.7 8.7 4.2 1.1 2.8 3.0 6.7 6.3 8.2 1.7 2.9 2.8 3.8 3.0 1.9 3.7 4.1 5.6 3.2 1.4 4.9 3.0 2.6 3.6 20.4 3.0 4.6 6.1 5.8 1.4 3.2 1.9 2.8 16.0 3.8 4.9 8.3 8.7 13.1 2.7 6.7 5.8 5.4 7.4 7.6 8.7 0.0 8.5 9.7 3.4 6.4 6.3 7.1 6.4 0.0 5.1 1.5 3.7 5.9 7.8 6.4 0.6 13.1 5.9 1.8 12.1 7.0 3.8 5.2 3.7 0.0 9.0 12.2 1.4 3.4 7.3 4.3 3.4 0.5 4.2 2.6 6.0 8.0 8.9 5.1 19.9 5.7 10.3 3.7 8.0 2.6 6.9 6.8 1.8 9.3 3.3 4.0 1.9 0.0 3.5 2.2 5.6 0.0 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.2 0.0 1.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 2.4 2.4 3.4 1.9 1.8 3.3 2.8 3.0 2.8 3.0 3.0 2.8 1.3 3.2 7.2 14.4 0.4 1.0 5.7 1.6 6.2 2.0 2.9 2.4 4.1 4.3 3.0 3.7 2.1 9.4 0.1 0.5 3.9 5.1 18.2 1.5 4.0 1.7 4.2 3.0 7.5 3.8 5.4 5.3 4.1 1.0 5.7 6.1 2.9 8.0 2.9 0.0 5.8 2.4 0.0 0.8 0.7 4.0 4.7 1.0 0.0 3.7 0.0 3.2 0.0 11.1 4.7 3.8 0.3 8.6 0.1 5.5 0.1 4.5 3.3 0.9 0.0 5.7 2.8 71.5 18.2 6.1 0.6 7.3 0.6 6.6 1.5 3.2 TYROBP "DAP12, KARAP, PLO-SL, PLOSL" ENSG00000011600 "Transmembrane immune signaling adaptor TYROBP" O43914 19 35904401-35908295 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 596.8;lymphoid tissue: 423.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3777.1;Kupffer cells: 3698.1;Langerhans cells: 1990.8;Macrophages: 2837.1;monocytes: 3371.2;NK-cells: 1772.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 6415.4" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "HMC-1: 678.1;THP-1: 390.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009493, HPA041899" Enhanced Supported "Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB009493: AB_638987, HPA041899: AB_10795266" "unprognostic (7.09e-2)" "unprognostic (8.38e-3)" "unprognostic (7.87e-2)" "unprognostic (4.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.39e-1)" "unprognostic (5.27e-2)" "unprognostic (8.04e-2)" "unprognostic (2.07e-2)" "unprognostic (2.47e-1)" "unprognostic (2.91e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.47e-2)" "unprognostic (1.72e-2)" "unprognostic (4.27e-2)" "unprognostic (4.39e-2)" 126.3 76.1 55.8 234.3 54.3 596.8 59.1 58.6 116.8 44.3 61.4 62.0 70.6 25.9 15.0 28.1 43.7 105.0 39.7 53.0 66.4 34.4 85.5 261.5 161.0 81.7 64.0 18.3 24.7 22.0 27.0 124.7 74.8 31.7 49.8 3.9 38.3 26.7 10.6 21.5 78.8 68.0 74.1 423.3 43.1 15.0 74.0 52.5 21.9 31.6 36.6 131.7 21.5 114.4 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 56.7 0.0 0.0 0.5 33.2 678.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 49.1 0.3 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.3 0.5 0.0 0.0 0.2 0.9 0.0 390.6 0.0 0.0 0.3 0.8 0.1 0.4 0.1 1.0 0.1 10.8 0.1 974.2 4983.5 2573.9 468.0 3367.8 246.5 22.4 9.5 64.2 1912.0 8.4 11.7 51.2 6415.4 1664.1 3413.8 1653.1 9.5 5260.2 55.8 54.3 58.6 116.8 53.0 66.4 81.7 64.0 74.8 74.1 74.0 114.4 24.5 57.7 168.4 0.0 50.9 55.2 2.0 0.0 1.2 0.1 11.5 43.3 6.8 34.3 43.4 20.2 0.0 19.8 987.6 1.7 1.9 2.1 3.9 1.3 1.4 47.1 0.0 87.8 0.1 5.8 28.0 24.9 5.6 1.5 753.7 0.3 73.2 25.0 3777.1 0.0 0.1 0.2 0.0 3698.1 1990.8 11.6 9.3 2837.1 56.9 18.7 3371.2 0.6 1772.4 0.0 0.1 1.3 2.3 1.2 19.4 1.5 0.5 8.9 20.5 1.8 78.9 5.3 10.0 0.9 3.0 4.9 44.6 38.9 236.5 0.1 0.5 1.8 UBB "FLJ25987, MGC8385" ENSG00000170315 "Ubiquitin B" P0CG47 17 16380798-16382745 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013048, HPA041344, HPA049132" Supported NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" "CAB013048: AB_2533002, HPA041344: AB_2677422, HPA049132: AB_2680646" "unprognostic (1.16e-1)" "unprognostic (2.98e-1)" "unprognostic (2.55e-1)" "unprognostic (7.34e-2)" "unprognostic (3.86e-1)" "unprognostic (9.32e-2)" "unprognostic (1.29e-3)" "unprognostic (2.48e-2)" "unprognostic (5.81e-2)" "unprognostic (2.15e-3)" "unprognostic (2.88e-2)" "unprognostic (1.45e-2)" "prognostic favorable (1.07e-4)" "unprognostic (1.02e-1)" "unprognostic (1.02e-1)" "unprognostic (1.18e-1)" "unprognostic (1.69e-1)" 942.4 1676.7 1564.8 674.6 1589.2 2376.9 770.4 1662.2 2231.7 812.8 1565.4 1065.5 1179.6 788.9 1367.0 656.3 656.8 813.0 1668.3 1644.2 1719.8 1593.6 2982.1 1046.3 1002.7 1672.3 1765.4 726.2 1305.1 1677.7 1373.8 1012.3 1713.9 808.0 1097.8 566.0 1294.6 861.8 2656.6 692.3 1134.0 932.4 1670.6 1078.8 1245.6 1591.8 1597.4 1226.8 1181.5 2162.1 993.0 974.7 689.1 1980.8 1646.5 3022.4 1559.8 1912.1 1530.0 963.9 1131.3 1609.5 2166.2 2855.8 2453.4 2916.5 1270.4 1662.3 2631.3 1916.6 1678.5 1295.4 0.8 1054.2 3076.0 2126.4 2231.3 1649.8 1653.1 2183.7 1022.3 6.6 2162.4 1468.9 1010.2 2183.4 848.2 1486.0 1582.3 1562.2 1888.9 1530.9 1743.0 3858.5 2354.7 2086.6 1288.4 4642.0 1177.2 2185.1 1984.7 1484.1 2312.8 1911.4 1179.0 1757.0 2109.6 1239.7 1454.4 3025.5 1392.6 1936.0 1152.7 1417.8 867.8 1087.6 2507.7 845.7 1238.7 1366.4 1688.3 1757.9 1356.3 5348.4 1684.4 3262.9 2632.2 2121.6 2131.1 3065.4 2048.1 2372.7 1501.1 2872.4 1787.4 2146.5 981.5 3290.2 1875.7 2799.7 2592.8 7841.1 1564.8 1589.2 1662.2 2231.7 1644.2 1719.8 1672.3 1765.4 1713.9 1670.6 1597.4 1980.8 1607.0 1003.2 1168.4 46.7 786.3 979.5 1548.2 1890.9 796.2 426.2 763.6 1161.1 370.3 948.0 1262.5 551.8 120.9 1661.1 1082.7 1377.9 1829.3 1114.8 3648.2 961.6 510.0 870.9 922.4 4506.0 29.1 880.2 996.8 1202.3 1270.6 799.9 1800.7 412.4 669.3 1509.8 1168.9 233.9 37.3 1351.2 1310.2 589.0 1180.7 2126.9 592.4 826.6 1812.5 50.6 1001.9 912.0 1051.5 30.7 133.6 751.3 1879.5 775.2 700.4 974.6 1970.0 3101.7 2080.6 506.8 880.9 714.4 3554.9 3297.7 1090.7 739.1 1112.3 1815.4 1231.6 935.0 993.8 1036.2 UBE2G1 "UBC7, UBE2G" ENSG00000132388 "Ubiquitin conjugating enzyme E2 G1" P62253 17 4269259-4366628 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 210.2" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 286.0;Late spermatids: 248.3;Suprabasal keratinocytes: 239.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045681, HPA050551" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 13: T-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 28: Keratinocytes - Keratinization" "Nucleoplasm, Cytosol" "HPA045681: AB_2679417, HPA050551: AB_2681171" "unprognostic (1.57e-3)" "unprognostic (1.94e-1)" "unprognostic (2.34e-2)" "unprognostic (1.80e-2)" "unprognostic (5.16e-2)" "unprognostic (5.84e-2)" "unprognostic (1.87e-1)" "unprognostic (2.64e-2)" "unprognostic (5.13e-2)" "unprognostic (1.86e-1)" "unprognostic (2.80e-1)" "unprognostic (1.67e-2)" "unprognostic (9.99e-2)" "unprognostic (2.16e-1)" "unprognostic (4.58e-2)" "unprognostic (3.97e-2)" "unprognostic (6.50e-2)" 21.0 19.1 15.8 25.4 21.4 31.5 20.1 21.0 24.3 25.2 11.6 39.7 22.5 22.7 14.7 52.2 16.3 16.0 37.9 16.1 18.7 27.0 30.3 15.6 38.8 21.5 19.2 15.6 18.4 21.5 9.7 18.9 21.7 22.6 24.2 17.5 21.0 20.8 210.2 28.0 23.6 27.2 20.3 20.7 21.8 23.2 21.0 24.9 16.1 84.1 46.4 24.5 32.1 26.5 54.5 57.8 52.7 38.9 42.2 44.3 74.9 51.7 41.4 48.2 42.1 40.0 27.0 84.5 52.8 51.2 39.4 57.2 66.3 48.1 77.2 44.8 53.9 31.7 28.6 45.9 41.3 46.5 57.4 38.0 70.3 45.8 66.1 33.8 65.6 55.8 56.5 88.9 40.1 24.3 59.4 42.5 58.2 40.1 29.6 76.1 27.9 78.1 56.4 35.1 22.7 42.3 48.9 41.8 41.6 77.4 41.1 29.9 49.6 48.1 36.8 57.0 58.7 34.3 43.8 118.9 36.9 42.8 37.7 13.3 15.8 39.0 22.2 16.8 29.9 34.1 28.3 29.1 20.2 24.4 28.3 28.9 28.1 32.5 18.6 14.8 28.9 21.8 15.8 21.4 21.0 24.3 16.1 18.7 21.5 19.2 21.7 20.3 21.0 26.5 28.3 22.4 14.4 31.3 70.6 286.0 36.5 47.8 111.5 18.8 47.0 31.0 67.6 27.1 32.2 25.8 6.2 47.0 47.8 41.4 82.2 30.9 139.5 36.7 25.7 35.5 38.4 26.5 47.9 26.7 59.6 31.1 32.6 39.9 21.0 13.9 31.1 62.3 48.1 15.2 46.3 38.3 44.7 36.5 81.1 248.3 19.6 35.7 67.6 30.9 43.1 28.7 36.0 36.2 84.4 43.0 30.4 21.1 154.3 65.7 40.4 75.6 35.4 17.1 6.6 25.9 43.5 70.8 50.8 85.3 239.7 66.8 58.2 13.8 30.1 54.0 UBR3 "DKFZp434P117, FLJ37422, KIAA2024, ZNF650" ENSG00000144357 "Ubiquitin protein ligase E3 component n-recognin 3" Q6ZT12 2 169827454-170084131 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 71.2;tongue: 87.1" "Cell type enhanced" "Detected in all" "Astrocytes: 162.6;Excitatory neurons: 305.1;Inhibitory neurons: 302.0;Oligodendrocyte precursor cells: 232.2;Oligodendrocytes: 288.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035390 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nucleoli" "HPA035390: AB_10670699" "unprognostic (1.35e-2)" "unprognostic (1.24e-1)" "unprognostic (1.59e-2)" "unprognostic (1.27e-1)" "unprognostic (2.07e-2)" "unprognostic (1.24e-1)" "unprognostic (1.00e-1)" "unprognostic (3.91e-2)" "unprognostic (1.05e-1)" "unprognostic (1.24e-1)" "unprognostic (1.76e-1)" "unprognostic (1.26e-1)" "unprognostic (3.19e-2)" "unprognostic (5.56e-2)" "unprognostic (2.01e-1)" "unprognostic (3.38e-1)" "unprognostic (2.18e-1)" 14.2 12.4 4.4 7.7 5.8 7.4 9.2 5.9 8.5 10.9 2.8 8.8 8.1 10.1 6.9 12.8 8.4 9.3 29.4 8.0 3.3 15.2 21.0 8.8 7.2 2.4 2.7 10.2 11.9 21.5 2.1 8.7 3.3 13.1 8.5 21.2 11.5 10.3 71.2 9.2 7.5 11.1 3.2 8.8 9.3 9.7 3.4 9.5 17.9 87.1 7.3 11.0 2.3 8.4 14.8 12.4 12.9 17.1 25.0 19.7 10.8 26.1 15.0 14.7 11.8 19.1 9.1 16.7 22.2 20.5 12.0 19.0 15.5 13.2 18.2 17.4 13.4 61.1 12.6 20.3 12.4 20.4 18.9 11.9 12.1 19.3 12.9 11.7 14.8 8.3 32.4 17.6 25.6 14.0 13.3 10.0 10.1 14.9 10.2 12.6 21.1 17.8 10.5 20.5 25.1 13.7 18.4 16.7 10.6 10.2 10.9 11.4 18.9 22.1 9.0 17.5 16.7 14.2 11.9 15.1 18.2 11.8 12.5 0.0 0.6 0.5 0.9 0.6 1.3 0.6 0.5 0.8 0.9 0.3 0.9 1.2 0.6 0.8 0.5 0.7 1.0 0.4 4.4 5.8 5.9 8.5 8.0 3.3 2.4 2.7 3.3 3.2 3.4 8.4 19.0 44.8 26.9 162.6 16.3 25.9 12.4 14.8 20.5 46.3 15.8 8.9 109.7 17.2 20.0 12.9 81.3 19.7 22.9 17.1 3.9 8.7 7.6 16.8 21.9 26.4 16.7 24.4 305.1 11.0 8.4 22.2 23.4 22.0 16.5 22.7 30.4 39.0 10.2 63.9 302.0 11.3 22.4 20.9 18.7 10.2 25.7 18.7 16.0 110.5 18.7 61.7 14.4 232.2 288.0 10.7 15.0 19.2 21.3 20.9 15.3 10.0 13.4 51.5 26.3 29.0 21.8 12.4 8.6 22.9 29.0 23.0 18.1 17.3 13.2 17.2 UGP2 "SVUGP2, UGP1, UGPP1" ENSG00000169764 "UDP-glucose pyrophosphorylase 2" Q16851 2 63840952-63891562 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 858.6;tongue: 756.1" "Cell type enhanced" "Detected in all" "Distal enterocytes: 849.9;Hepatocytes: 559.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 417.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034696, HPA034697, HPA064836" Enhanced Approved Nucleoplasm,Centrosome,Mitochondria NA NA 13000000 "Cluster 38: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 30: Mammary glandular cells - Lactation" "Centrosome, Mitochondria" Nucleoplasm "HPA034696: AB_10670171, HPA034697: AB_2674287, HPA064836: AB_2685365" "unprognostic (1.00e-2)" "unprognostic (6.93e-2)" "unprognostic (5.12e-2)" "unprognostic (1.06e-1)" "unprognostic (2.65e-2)" "unprognostic (1.91e-1)" "prognostic favorable (2.50e-5)" "unprognostic (2.20e-1)" "unprognostic (3.01e-1)" "unprognostic (1.84e-1)" "unprognostic (1.57e-2)" "unprognostic (8.31e-2)" "unprognostic (1.03e-1)" "unprognostic (1.25e-2)" "unprognostic (3.93e-2)" "unprognostic (3.81e-1)" "unprognostic (8.44e-2)" 267.3 72.0 79.8 65.8 89.3 40.1 119.7 72.7 109.8 65.9 78.8 177.9 66.0 75.2 50.6 97.5 68.9 60.7 232.5 87.9 81.4 105.4 858.6 65.4 65.7 77.7 77.0 47.0 74.4 113.3 49.8 137.8 77.6 57.4 159.3 36.8 92.9 66.2 498.0 59.1 67.6 78.5 73.2 50.8 69.5 38.3 83.3 106.2 64.5 756.1 73.7 88.4 63.7 91.8 122.3 77.6 63.1 42.0 176.1 222.4 220.6 129.1 116.1 82.7 89.4 170.0 104.5 149.5 48.3 165.6 79.9 57.4 73.4 102.6 137.0 99.2 35.7 86.5 50.4 117.9 87.0 79.1 73.9 148.1 175.8 76.1 80.3 108.4 119.4 38.9 48.2 58.1 327.8 56.7 104.6 75.2 122.9 207.7 50.1 80.4 117.9 84.5 147.4 77.7 36.5 29.6 103.3 149.8 64.3 162.6 51.7 59.2 144.3 84.4 125.9 113.8 90.5 101.3 51.4 174.9 99.2 122.7 225.7 417.1 33.0 53.1 48.0 40.7 51.8 33.0 53.6 50.1 27.9 31.8 57.6 53.6 45.4 70.0 39.5 29.7 127.2 62.0 79.8 89.3 72.7 109.8 87.9 81.4 77.7 77.0 77.6 73.2 83.3 91.8 73.4 28.9 54.0 107.4 65.3 75.8 87.8 245.9 34.7 49.6 360.6 87.1 264.3 104.4 171.6 47.8 64.6 414.3 81.1 849.9 242.6 140.6 91.5 53.0 106.3 69.8 44.5 56.0 86.1 103.6 445.5 159.3 79.0 49.5 67.8 42.4 63.5 559.4 120.9 87.5 78.4 179.8 144.5 102.4 90.2 86.1 79.2 89.1 96.0 62.8 139.7 58.8 154.5 37.2 79.3 91.6 313.9 77.5 60.7 81.2 176.2 284.4 139.3 57.3 72.3 50.5 129.2 84.9 54.9 50.9 57.8 472.8 143.1 90.6 189.5 109.1 UGT1A1 "GNT1, UGT1, UGT1A" ENSG00000241635 "UDP glucuronosyltransferase family 1 member A1" P22309 2 233760270-233773300 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 26 "intestine: 201.2;liver: 322.4" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 105.0" "Cancer enriched" "Detected in some" 19 "liver cancer: 16.4" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.4" "Cell line enhanced" "Detected in some" "HaCaT: 14.0;OE19: 64.5;RT4: 34.7" "Not detected" "Not detected" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (7.28e-2)" "unprognostic (2.49e-2)" "unprognostic (3.60e-1)" "unprognostic (5.69e-2)" "unprognostic (4.17e-3)" "unprognostic (6.31e-3)" "unprognostic (1.94e-5)" "unprognostic (2.78e-3)" "unprognostic (2.99e-4)" 0.1 0.1 0.6 0.2 0.5 0.5 0.2 1.5 0.8 0.1 0.2 3.0 201.2 0.2 0.4 3.5 0.1 1.0 0.2 0.4 0.8 4.0 322.4 0.2 0.3 0.2 0.2 0.2 0.1 0.1 0.0 0.1 0.2 0.2 2.4 0.9 0.5 0.3 0.1 1.8 79.2 0.1 0.0 0.2 2.4 0.6 0.3 0.1 0.2 0.1 0.3 10.0 0.9 0.6 0.3 1.1 0.2 0.2 0.1 0.1 0.6 0.0 0.0 0.0 0.1 5.4 0.3 0.2 2.5 0.1 0.1 14.0 0.0 0.2 0.0 0.2 0.1 0.1 0.6 1.6 0.0 0.5 0.2 0.2 0.6 0.0 0.0 0.1 0.0 0.3 0.2 0.6 0.0 0.8 0.1 0.3 0.5 64.5 6.5 0.1 0.1 0.6 0.0 34.7 0.2 0.4 2.6 0.4 0.0 0.2 0.2 0.0 0.1 0.2 0.1 0.3 0.0 0.2 0.2 0.1 0.7 0.4 0.2 0.9 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.1 1.4 0.3 0.1 0.1 0.1 0.0 0.6 0.5 1.5 0.8 0.4 0.8 0.2 0.2 0.2 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.6 0.0 0.0 0.0 0.0 0.0 3.7 1.8 0.0 0.0 0.0 1.8 0.0 0.1 2.9 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.1 105.0 0.0 0.0 0.0 0.4 0.0 2.4 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.6 0.0 0.1 6.9 14.6 2.2 1.5 0.0 0.0 0.4 0.1 0.2 0.1 1.5 0.0 0.0 0.1 0.0 0.7 7.3 UGT1A3 UGT1C ENSG00000243135 "UDP glucuronosyltransferase family 1 member A3" P35503 2 233729108-233773299 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "liver: 73.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "liver cancer: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HaCaT: 11.4" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (5.15e-2)" "unprognostic (9.93e-2)" "unprognostic (2.97e-1)" "unprognostic (4.59e-2)" "unprognostic (1.04e-4)" "unprognostic (8.22e-2)" "unprognostic (2.08e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 73.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 5.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT1A4 "HUG-BR2, UGT1D" ENSG00000244474 "UDP glucuronosyltransferase family 1 member A4" P22310 2 233718736-233773300 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "liver: 391.7" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 15.1" "Cancer enriched" "Detected in single" 487 "liver cancer: 24.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (9.89e-3)" "unprognostic (6.77e-5)" "unprognostic (2.59e-1)" "unprognostic (3.50e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 391.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT2B11 ENSG00000213759 "UDP glucuronosyltransferase family 2 member B11" O75310 4 69199951-69214748 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "breast: 239.4" "Group enriched" "Detected in some" 4 "Breast glandular cells: 13.7;Cholangiocytes: 7.2" "Group enriched" "Detected in some" 17 "breast cancer: 17.4;liver cancer: 13.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 42 "basophil: 4.7;eosinophil: 3.5" "Lineage enriched" "Detected in single" 47 "granulocytes: 4.7" "Not detected" "Not detected" HPA045108 Uncertain NA NA "Cluster 46: Basophils - DNA binding" "Cluster 5: Breast - Unknown function" "Cluster 35: Glandular cells - Unknown function" "HPA045108: AB_2679218" "unprognostic (1.12e-1)" "unprognostic (1.18e-3)" "unprognostic (1.49e-1)" "unprognostic (6.53e-2)" "unprognostic (2.26e-2)" "unprognostic (1.65e-1)" "unprognostic (7.84e-3)" "unprognostic (5.47e-1)" "unprognostic (1.32e-1)" "unprognostic (1.51e-3)" 0.1 0.0 0.0 0.1 0.0 0.1 239.4 0.0 0.0 0.1 0.0 0.1 0.7 0.0 0.9 0.0 0.5 11.4 0.0 0.0 0.0 3.6 9.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.7 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.5 0.0 7.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 UGT2B4 UGT2B11 ENSG00000156096 "UDP glucuronosyltransferase family 2 member B4" P06133 4 69480165-69526014 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 107 "liver: 1273.7" "Cell type enriched" "Detected in some" 22 "Hepatocytes: 883.5" "Cancer enriched" "Detected in some" 96 "liver cancer: 351.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "RH-30: 4.6" "CAB033260, HPA045108" Enhanced "Intracellular and membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 2: Hepatocytes - Metabolism" "CAB033260: AB_2241496, HPA045108: AB_2679218" "unprognostic (7.46e-2)" "unprognostic (1.50e-1)" "unprognostic (9.37e-2)" "unprognostic (1.51e-1)" "unprognostic (2.47e-2)" "unprognostic (1.47e-1)" "unprognostic (9.43e-3)" "unprognostic (3.52e-1)" 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 11.9 0.0 0.0 1.3 1273.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.4 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 10.7 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 11.7 883.5 0.1 0.0 0.1 0.0 0.0 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 UHRF1BP1L KIAA0701 ENSG00000111647 "UHRF1 binding protein 1 like" A0JNW5 12 100028455-100142874 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 75.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039671, HPA075150" Uncertain Uncertain Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Vesicles, Cytosol" "HPA039671: AB_10794201, HPA075150: " "unprognostic (4.80e-2)" "unprognostic (3.17e-1)" "unprognostic (2.34e-2)" "unprognostic (1.14e-1)" "unprognostic (8.96e-2)" "unprognostic (7.36e-2)" "unprognostic (8.10e-2)" "unprognostic (5.75e-3)" "unprognostic (2.06e-1)" "unprognostic (5.43e-2)" "unprognostic (1.88e-2)" "unprognostic (2.53e-1)" "unprognostic (2.94e-3)" "unprognostic (6.84e-2)" "unprognostic (1.25e-1)" "unprognostic (3.81e-2)" "unprognostic (1.28e-2)" 8.7 10.9 6.2 10.2 7.7 32.9 8.8 11.0 11.5 7.2 9.9 8.3 8.4 7.5 7.0 7.0 6.3 8.9 7.9 13.2 6.2 12.3 24.6 7.7 9.2 4.9 5.4 7.5 3.8 13.6 5.2 9.0 4.8 9.0 7.9 14.6 6.4 8.0 19.8 5.9 7.1 8.8 4.6 9.2 6.0 14.0 3.7 8.4 10.9 14.6 7.0 10.1 5.2 9.2 18.6 19.7 10.8 11.2 16.4 23.1 21.6 28.3 28.4 22.4 16.3 14.8 6.2 16.0 7.2 29.1 13.1 6.9 20.4 9.7 21.5 42.7 10.0 10.7 14.1 17.3 15.1 20.4 16.8 13.1 8.0 27.0 18.6 20.7 16.0 11.0 8.6 16.2 22.1 10.3 13.1 17.5 18.7 6.3 17.7 14.7 19.2 15.7 11.4 32.2 18.3 11.4 21.4 24.5 8.5 9.2 21.9 23.0 12.7 24.6 13.2 21.5 20.1 19.1 35.2 22.3 12.4 15.1 15.2 21.6 11.4 7.8 3.6 12.3 5.3 5.5 4.0 4.1 12.8 4.5 3.4 4.2 33.9 5.9 10.9 7.6 5.2 5.4 6.2 7.7 11.0 11.5 13.2 6.2 4.9 5.4 4.8 4.6 3.7 9.2 10.6 28.9 8.7 27.1 18.2 12.7 17.2 5.0 19.9 11.9 9.3 7.5 15.7 1.5 12.6 9.2 4.2 4.7 15.0 10.9 5.9 6.0 35.1 15.7 23.7 8.6 5.4 9.4 75.2 5.9 8.9 24.7 7.7 9.9 24.1 6.3 5.3 18.5 11.2 15.2 54.2 2.1 4.1 23.3 21.4 5.3 7.2 29.5 10.6 45.0 25.7 8.3 8.2 37.2 29.5 5.9 7.4 7.9 12.5 18.5 8.9 14.9 21.8 12.0 0.0 23.3 15.1 24.1 19.1 14.9 11.6 10.9 15.7 8.3 5.7 11.9 ULBP2 RAET1H ENSG00000131015 "UL16 binding protein 2" Q9BZM5 6 149942014-149949235 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 6.1" "Cell type enhanced" "Detected in many" "Adipocytes: 28.9;Basal respiratory cells: 17.9;dendritic cells: 12.1" "Cancer enhanced" "Detected in all" "head and neck cancer: 12.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.7" "Lineage enriched" "Detected in single" 6 "T-cells: 2.7" "Cell line enhanced" "Detected in many" "SiHa: 66.7;U-2197: 47.4" "CAB018974, HPA066741" Approved Supported "Vesicles,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 27: Brain & Skin - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Plasma membrane" "CAB018974: , HPA066741: " "unprognostic (2.09e-5)" "prognostic unfavorable (8.07e-4)" "unprognostic (2.38e-3)" "unprognostic (3.90e-1)" "prognostic unfavorable (2.44e-4)" "unprognostic (1.26e-2)" "unprognostic (2.38e-3)" "unprognostic (1.47e-1)" "unprognostic (1.02e-1)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (1.75e-2)" "unprognostic (1.42e-4)" "unprognostic (1.68e-1)" "unprognostic (2.06e-1)" "unprognostic (2.14e-1)" "unprognostic (4.86e-1)" 1.5 0.7 1.3 0.6 1.6 1.8 0.7 1.6 2.6 0.9 0.7 0.2 0.2 0.1 0.1 6.1 0.2 0.5 2.0 3.0 1.0 2.1 0.5 3.4 0.3 1.8 1.2 0.0 0.4 0.6 0.5 1.6 1.8 0.2 0.1 0.2 0.7 0.1 0.3 0.5 0.2 0.7 0.8 0.2 0.3 1.5 1.1 0.7 1.2 0.7 0.8 1.4 1.6 1.7 19.9 1.8 0.5 6.1 1.1 5.6 3.3 20.1 11.8 20.6 16.8 7.4 11.0 0.0 29.9 23.0 29.6 13.9 7.6 18.4 11.8 9.1 3.9 1.1 2.8 0.0 7.1 0.0 1.5 2.7 13.9 18.3 8.0 16.7 11.9 16.6 2.5 0.0 15.4 13.9 1.8 0.0 0.0 3.6 10.2 3.0 4.5 0.0 29.0 5.7 0.6 0.0 66.7 1.4 1.9 3.2 1.8 8.5 18.8 13.5 17.1 47.4 23.5 0.0 0.1 0.9 19.2 10.7 9.9 0.0 0.0 0.0 2.7 0.0 0.3 0.0 0.8 1.5 0.0 0.0 0.3 1.8 0.0 0.4 0.0 0.0 1.7 0.5 1.3 1.6 1.6 2.6 3.0 1.0 1.8 1.2 1.8 0.8 1.1 1.7 28.9 0.0 1.3 0.0 1.2 3.7 6.5 17.9 7.4 0.0 1.3 4.4 0.3 0.0 9.4 1.8 0.0 0.0 12.1 0.5 0.0 7.5 7.0 0.3 0.5 9.1 0.0 0.0 3.0 8.8 0.5 3.0 1.1 0.2 0.0 0.1 7.1 0.2 2.2 0.0 0.7 0.3 2.0 0.8 2.1 8.0 0.0 3.1 1.8 0.0 0.0 0.4 4.1 0.5 0.3 4.5 0.0 0.0 1.4 1.4 0.0 0.1 1.4 0.0 0.0 1.0 4.2 3.1 7.0 11.8 2.8 0.0 11.0 0.6 0.4 5.2 UMAD1 "RPA3-AS1, RPA3OS" ENSG00000219545 "UBAP1-MVB12-associated (UMA) domain containing 1" C9J7I0 7 7640711-7968020 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 96.7;Inhibitory neurons: 114.3;Microglial cells: 79.6;Oligodendrocyte precursor cells: 80.9;Oligodendrocytes: 119.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044806 Approved Approved Nucleoplasm NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA044806: AB_10961141" "unprognostic (4.86e-2)" "unprognostic (1.48e-1)" "unprognostic (1.68e-1)" "unprognostic (1.23e-1)" "unprognostic (9.08e-3)" "unprognostic (9.24e-2)" "unprognostic (6.86e-3)" "unprognostic (4.87e-1)" "unprognostic (2.56e-1)" "unprognostic (6.57e-2)" "unprognostic (1.19e-1)" "unprognostic (2.43e-1)" "prognostic favorable (1.73e-8)" "unprognostic (6.66e-3)" "unprognostic (8.34e-2)" "unprognostic (7.69e-2)" "unprognostic (3.58e-1)" 9.2 16.5 5.5 11.2 5.8 9.5 10.3 5.6 6.2 10.1 7.0 12.8 15.4 10.3 11.4 8.9 10.2 10.7 13.7 4.9 8.3 17.2 14.3 12.0 15.7 6.9 7.3 13.6 36.1 29.7 10.3 9.2 7.5 18.9 11.6 11.5 20.6 11.7 11.3 7.0 16.6 9.8 6.1 10.3 23.0 5.8 7.0 18.4 24.6 10.5 13.4 12.3 8.4 7.1 24.7 17.9 9.0 10.5 12.7 14.9 10.3 14.9 17.2 11.5 17.4 7.6 17.9 13.4 15.4 9.4 46.3 15.7 10.4 15.0 14.3 10.1 8.1 7.3 12.4 8.9 14.2 13.6 16.3 14.2 18.6 16.6 12.7 13.5 7.1 17.2 15.1 40.0 15.4 19.9 12.4 7.4 16.2 16.5 14.8 13.6 21.3 21.3 20.9 11.1 3.6 14.8 21.0 26.7 21.6 26.5 20.8 16.3 7.8 11.7 27.2 23.3 15.2 28.6 34.2 15.5 26.4 19.2 36.8 51.8 16.0 43.5 19.3 21.5 23.9 28.8 27.2 24.2 13.8 26.0 31.8 23.8 46.1 18.5 24.1 16.3 38.7 17.9 5.5 5.8 5.6 6.2 4.9 8.3 6.9 7.3 7.5 6.1 7.0 7.1 12.1 25.6 11.9 58.8 22.8 0.0 27.7 0.0 12.0 6.5 13.8 12.3 10.9 11.5 9.9 14.7 14.6 16.7 7.7 7.6 39.2 8.4 7.1 9.7 7.6 7.1 6.1 6.7 96.7 14.5 23.6 11.4 33.1 10.6 15.2 3.8 6.4 9.5 16.8 15.2 114.3 13.3 0.0 13.2 0.0 3.7 13.4 12.9 0.0 79.6 8.9 11.4 16.5 80.9 119.3 10.4 9.0 7.9 28.4 19.3 16.8 34.2 9.5 9.8 26.3 12.0 9.6 4.8 5.0 12.6 0.0 21.2 17.0 7.6 7.7 21.2 UQCRC1 "D3S3191, QCR1, UQCR1" ENSG00000010256 "Ubiquinol-cytochrome c reductase core protein 1" P31930 3 48599002-48610976 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 766.7;tongue: 882.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 662.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002815, HPA003525, CAB033782" Enhanced Supported Mitochondria NA NA 250000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB033782: AB_2213631, HPA002815: AB_1080486, HPA003525: AB_1080484" "unprognostic (1.29e-1)" "unprognostic (3.15e-3)" "unprognostic (6.91e-3)" "unprognostic (1.06e-1)" "unprognostic (1.66e-1)" "unprognostic (9.91e-2)" "unprognostic (8.53e-2)" "unprognostic (1.99e-1)" "unprognostic (3.11e-2)" "unprognostic (9.14e-2)" "unprognostic (3.37e-1)" "unprognostic (7.20e-2)" "prognostic favorable (2.35e-10)" "unprognostic (5.37e-2)" "unprognostic (2.35e-1)" "unprognostic (1.02e-1)" "unprognostic (6.72e-2)" 66.0 58.2 93.7 46.9 97.1 62.4 55.0 117.3 110.1 50.7 127.2 156.9 156.3 35.5 50.4 78.9 66.2 33.9 387.7 96.7 115.0 131.3 149.0 42.1 42.8 111.0 101.7 36.1 87.4 192.2 30.6 56.0 114.6 51.8 129.6 52.9 105.9 77.5 766.7 78.6 125.4 62.8 99.3 41.0 103.3 52.1 111.6 72.7 48.4 882.7 58.0 63.5 40.0 101.4 118.2 169.6 136.7 145.0 147.5 117.0 225.2 129.4 206.1 196.5 178.9 272.8 107.1 193.4 94.4 143.2 274.1 123.6 171.6 280.9 91.7 138.3 173.8 214.7 186.7 317.1 186.9 164.4 152.2 150.9 293.6 183.2 274.6 167.5 172.5 173.7 110.5 107.1 152.5 192.0 156.7 241.6 157.6 229.6 324.2 103.4 138.1 273.5 235.8 178.7 84.4 107.5 182.8 218.7 211.8 92.0 163.1 178.0 112.5 107.7 153.7 179.5 272.4 124.8 121.4 136.5 192.7 233.9 319.0 251.3 643.7 325.4 204.7 665.7 193.7 260.0 203.5 206.1 593.3 227.7 177.1 175.2 158.2 194.4 608.0 235.0 258.1 988.2 93.7 97.1 117.3 110.1 96.7 115.0 111.0 101.7 114.6 99.3 111.6 101.4 31.5 57.7 50.4 17.3 59.0 117.6 164.6 339.4 103.6 41.9 59.3 46.1 662.2 140.2 139.2 121.4 29.2 334.4 28.0 550.2 365.9 163.7 155.0 64.0 41.6 53.4 144.5 80.6 16.9 166.3 311.1 78.2 167.7 61.5 82.4 72.5 49.6 188.0 238.2 40.4 22.0 319.6 223.8 118.1 85.4 331.9 58.4 107.7 119.2 12.2 129.1 67.1 51.5 14.6 12.5 163.5 333.3 70.7 117.6 78.4 553.4 398.4 104.7 65.0 59.2 61.2 153.0 110.3 74.7 173.0 105.4 336.7 50.8 172.1 416.8 153.4 UQCRC2 "QCR2, UQCR2" ENSG00000140740 "Ubiquinol-cytochrome c reductase core protein 2" P22695 16 21953288-21983660 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 722.2;tongue: 933.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 556.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007998, HPA019146" Enhanced Enhanced Mitochondria NA NA 180000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA007998: AB_1858648, HPA019146: AB_1858649" "unprognostic (1.33e-1)" "unprognostic (1.32e-1)" "unprognostic (1.49e-3)" "unprognostic (3.35e-1)" "unprognostic (1.26e-2)" "unprognostic (6.91e-2)" "unprognostic (2.71e-2)" "unprognostic (1.32e-1)" "unprognostic (1.72e-1)" "unprognostic (8.87e-2)" "unprognostic (1.67e-2)" "unprognostic (2.43e-2)" "prognostic favorable (6.58e-9)" "unprognostic (2.33e-1)" "unprognostic (9.78e-3)" "unprognostic (4.67e-3)" "unprognostic (7.36e-2)" 158.8 117.7 69.0 103.1 71.2 127.7 108.4 75.5 90.0 90.8 113.9 259.8 292.5 98.2 72.7 157.4 109.7 99.5 559.4 72.4 73.7 240.0 245.1 75.4 120.0 74.1 69.5 114.5 89.7 257.2 39.8 96.5 72.7 95.6 262.8 142.3 133.8 104.3 722.2 85.4 233.6 121.2 65.8 80.9 153.2 55.8 76.5 131.3 107.9 933.2 149.3 153.6 59.8 73.3 173.9 193.1 116.5 66.4 154.3 186.8 169.1 163.8 160.6 177.5 174.5 347.9 177.7 338.9 144.3 170.4 129.8 324.6 222.3 212.7 193.7 151.4 178.4 185.9 166.1 494.3 164.6 249.1 501.2 232.3 229.4 130.3 186.2 169.4 248.1 224.1 217.9 159.1 177.2 230.6 288.6 175.0 124.6 261.1 148.8 310.9 263.6 390.0 285.8 214.6 154.4 114.9 237.2 318.6 190.3 151.6 354.4 264.1 179.3 103.3 98.1 104.0 148.0 126.3 87.2 302.7 188.7 239.8 126.4 80.1 128.7 71.4 80.0 147.8 103.3 96.0 98.3 89.3 153.9 77.9 106.8 97.6 45.9 101.8 148.1 67.6 134.8 157.3 69.0 71.2 75.5 90.0 72.4 73.7 74.1 69.5 72.7 65.8 76.5 73.3 105.5 64.1 52.5 81.9 81.1 90.6 190.8 444.0 74.6 109.1 91.7 79.6 556.2 84.4 194.9 71.7 87.6 238.3 82.6 233.4 455.9 124.5 88.0 72.0 55.7 91.3 113.8 92.4 65.0 109.6 157.6 89.0 144.3 65.8 92.6 99.6 84.3 122.3 195.5 69.0 74.0 224.4 238.0 145.1 100.6 89.9 68.3 104.6 131.6 27.2 162.1 108.0 91.6 60.3 50.7 97.2 214.0 97.0 72.9 114.4 378.0 306.9 110.2 152.6 78.9 94.1 109.5 68.9 56.7 132.0 88.4 278.3 91.3 170.2 358.7 204.3 URI1 "C19orf2, FLJ10575, NNX3, PPP1R19, RMP, URI" ENSG00000105176 "URI1 prefoldin like chaperone" O94763 19 29923644-30016612 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Protein phosphatase inhibitor, Repressor" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 499.7;Late spermatids: 514.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071709 Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 24: B-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm Cytosol "HPA071709: AB_2686434" "unprognostic (4.22e-2)" "unprognostic (2.75e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (2.96e-2)" "unprognostic (2.98e-1)" "unprognostic (1.40e-3)" "unprognostic (8.12e-2)" "unprognostic (1.26e-2)" "unprognostic (4.42e-3)" "unprognostic (1.57e-1)" "unprognostic (3.71e-1)" "unprognostic (1.33e-1)" "unprognostic (6.14e-2)" "unprognostic (1.23e-2)" "unprognostic (1.42e-1)" "unprognostic (4.47e-2)" 25.0 30.6 29.7 24.8 39.6 36.4 36.7 57.8 40.7 27.9 21.0 26.1 23.5 34.2 32.3 28.5 30.2 25.1 28.1 25.0 36.8 25.6 30.5 22.9 39.9 35.9 32.3 44.1 21.9 31.4 11.0 24.1 34.5 37.7 32.1 32.4 27.2 30.4 52.8 44.9 23.4 22.8 28.4 30.0 25.0 51.6 30.9 31.7 55.4 36.2 37.3 24.8 10.7 45.6 64.8 85.9 39.5 61.7 27.5 39.8 66.5 41.3 34.4 29.5 33.7 45.4 41.5 99.7 79.4 48.2 23.4 44.6 84.8 52.7 66.5 69.7 48.5 90.8 44.3 59.7 39.7 88.5 37.3 35.1 70.6 25.7 95.7 31.7 22.1 58.2 109.7 27.2 37.4 55.3 58.0 37.1 37.1 83.4 26.2 56.7 73.2 40.5 19.4 75.3 63.4 49.7 47.1 56.3 62.2 41.7 23.5 54.8 29.1 72.1 63.9 35.6 63.3 74.4 86.2 67.7 35.5 76.5 44.4 3.4 1.3 1.8 2.9 1.4 2.5 1.9 2.6 3.0 1.1 4.5 3.1 3.1 0.1 2.2 1.4 1.6 2.2 0.8 29.7 39.6 57.8 40.7 25.0 36.8 35.9 32.3 34.5 28.4 30.9 45.6 51.6 44.8 38.8 59.1 48.6 57.0 95.3 19.4 40.5 60.6 67.6 68.1 52.8 48.6 28.2 40.5 25.0 19.2 84.4 21.7 105.7 16.9 499.7 48.5 82.8 32.5 28.9 38.5 79.9 27.8 28.7 45.6 41.3 41.8 30.9 54.5 31.8 50.9 15.4 52.2 122.3 36.5 18.3 33.6 24.0 514.0 43.8 32.9 32.0 74.9 25.0 58.5 70.0 137.7 178.4 19.4 23.7 41.3 53.3 123.9 19.4 85.2 38.8 59.8 13.1 82.3 48.5 72.2 52.2 44.8 73.6 13.1 74.2 91.6 37.0 94.3 USF3 KIAA2018 ENSG00000176542 "Upstream transcription factor family member 3" Q68DE3 3 113648385-113696646 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029243, HPA029245" Uncertain Uncertain Nucleoplasm,Nucleoli,Centrosome NA NA "Cluster 46: Basophils - DNA binding" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nucleoli" Centrosome "HPA029243: AB_10611114, HPA029245: AB_10600443" "unprognostic (2.80e-2)" "unprognostic (2.80e-1)" "unprognostic (4.21e-2)" "unprognostic (7.80e-2)" "unprognostic (2.25e-2)" "unprognostic (1.96e-2)" "unprognostic (3.53e-1)" "unprognostic (2.62e-2)" "unprognostic (2.93e-1)" "unprognostic (1.53e-2)" "unprognostic (8.74e-2)" "unprognostic (1.30e-1)" "prognostic favorable (1.74e-6)" "unprognostic (1.23e-1)" "unprognostic (1.97e-1)" "unprognostic (3.28e-1)" "unprognostic (5.55e-2)" 7.1 4.9 5.6 3.0 5.9 10.2 6.7 8.8 8.0 5.5 7.5 7.5 2.8 5.3 7.8 6.8 6.2 2.4 7.0 6.2 5.3 8.2 16.4 5.9 5.3 5.4 5.4 5.8 8.5 6.0 6.7 2.8 5.6 5.9 3.9 5.6 6.4 2.7 18.7 7.4 8.3 2.4 5.2 8.7 7.5 4.8 5.3 6.7 6.2 8.5 4.6 6.0 6.1 6.8 4.6 3.4 4.1 3.9 9.8 3.7 2.8 1.8 2.9 1.7 1.6 3.2 1.9 8.0 3.2 4.6 2.8 2.8 4.5 3.6 3.3 2.7 1.9 5.7 2.2 5.3 2.9 10.5 6.2 5.5 6.4 3.2 3.6 2.6 4.2 5.9 2.7 4.1 3.7 6.4 5.9 5.8 3.0 6.1 3.4 2.5 3.2 3.2 6.3 6.3 1.9 3.0 4.3 2.4 5.5 2.8 3.3 7.7 5.7 2.7 6.0 1.5 2.6 4.8 2.9 9.2 3.1 4.3 2.0 2.2 1.0 1.7 1.3 1.3 1.0 1.0 0.9 1.0 0.8 2.3 1.1 1.2 3.2 1.2 1.8 2.3 0.5 0.7 5.6 5.9 8.8 8.0 6.2 5.3 5.4 5.4 5.6 5.2 5.3 6.8 27.1 22.4 15.1 0.0 30.1 0.0 11.2 0.0 15.9 19.5 19.7 12.6 0.0 14.3 6.2 25.8 14.6 8.1 42.7 13.1 25.4 8.4 6.7 28.3 18.6 15.6 6.1 17.0 0.0 11.8 4.2 13.3 18.3 22.8 5.1 6.7 20.3 46.3 7.8 13.5 0.0 10.2 0.0 22.6 0.0 10.9 13.1 17.0 0.0 0.0 16.4 12.4 29.9 0.0 0.0 12.5 12.4 13.9 17.5 18.4 23.6 29.2 12.4 18.8 6.6 27.6 13.8 13.1 6.0 15.8 0.0 14.5 20.0 12.2 10.9 19.5 USH1C "AIE-75, DFNB18, harmonin, NY-CO-37, NY-CO-38, PDZ-73, PDZ73, PDZD7C" ENSG00000006611 "USH1 protein network component harmonin" Q9Y6N9 11 17493895-17544416 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Hearing" "Cancer-related genes, Deafness, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 97.8;kidney: 54.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 190.0;Muller glia cells: 163.6;Paneth cells: 203.0;Proximal enterocytes: 430.7;Proximal tubular cells: 190.3;Undifferentiated cells: 115.7" "Group enriched" "Detected in many" 7 "colorectal cancer: 34.5;pancreatic cancer: 18.8;renal cancer: 29.4;stomach cancer: 15.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CACO-2: 60.6;HeLa: 21.8;OE19: 57.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB013690, HPA027398, HPA027492, HPA028033" Enhanced Enhanced Cytosol No NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol "CAB013690: , HPA027398: AB_10601775, HPA027492: AB_10601898, HPA028033: AB_10601782" "unprognostic (3.60e-2)" "unprognostic (6.19e-2)" "unprognostic (2.36e-1)" "unprognostic (3.83e-2)" "unprognostic (1.98e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (2.22e-1)" "unprognostic (2.78e-1)" "unprognostic (1.51e-2)" "unprognostic (9.65e-2)" "prognostic favorable (9.41e-4)" "unprognostic (1.29e-2)" "unprognostic (1.88e-1)" "unprognostic (1.62e-1)" "unprognostic (2.61e-1)" 0.4 0.3 2.8 5.9 6.8 0.0 0.2 2.8 3.9 0.1 1.5 51.5 97.8 0.1 0.3 0.0 2.9 25.9 0.1 9.0 4.7 54.0 0.6 0.1 0.1 6.1 5.7 0.0 3.9 0.0 6.7 0.0 7.0 0.0 48.3 19.0 0.0 0.3 0.0 0.0 96.5 2.1 4.1 0.0 26.7 0.2 5.9 0.1 1.1 0.0 0.0 0.6 0.1 8.3 0.0 1.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 60.6 8.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 21.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 57.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 6.8 2.8 3.9 9.0 4.7 6.1 5.7 7.0 4.1 5.9 8.3 0.0 0.0 0.0 18.3 1.6 0.0 0.1 0.0 0.0 0.7 0.0 1.3 0.6 52.9 0.7 5.5 2.1 0.0 0.0 190.0 21.5 20.5 1.0 1.7 0.0 0.4 64.0 0.0 0.6 27.5 0.0 0.3 53.5 0.0 4.5 0.0 0.0 0.0 0.0 1.7 0.2 92.9 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 163.6 0.0 0.5 36.4 56.0 203.0 0.0 0.2 0.0 430.7 190.3 1.0 4.9 0.0 0.0 0.1 0.1 1.3 0.0 0.0 0.0 0.8 0.1 115.7 0.1 USP9X "DFFRX, FAF, MRX99" ENSG00000124486 "Ubiquitin specific peptidase 9 X-linked" Q93008 X 41085445-41236579 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Cell division, Chromosome partition, Mitosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011618, HPA047417, CAB070164" Approved Uncertain Vesicles NA NA 24000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Vesicles "CAB011618: AB_470860, CAB070164: AB_10011071, HPA047417: " "unprognostic (5.42e-3)" "unprognostic (6.42e-2)" "unprognostic (3.19e-3)" "unprognostic (2.94e-2)" "unprognostic (5.99e-2)" "unprognostic (4.76e-1)" "unprognostic (1.82e-2)" "unprognostic (4.07e-1)" "unprognostic (1.90e-1)" "unprognostic (1.72e-1)" "unprognostic (7.07e-2)" "unprognostic (1.09e-1)" "unprognostic (5.82e-2)" "unprognostic (1.59e-1)" "unprognostic (4.19e-2)" "unprognostic (2.78e-1)" "unprognostic (1.33e-1)" 16.4 16.8 11.9 14.3 13.9 18.2 14.2 12.7 12.8 15.3 14.3 14.8 13.6 15.4 14.9 14.1 16.0 13.0 15.3 14.3 13.2 17.8 33.9 14.4 15.8 12.2 13.1 13.4 16.0 30.0 10.2 18.4 13.8 12.3 13.7 22.0 11.5 15.3 39.1 13.8 14.3 16.3 12.5 13.3 13.8 17.5 12.8 18.8 19.5 28.4 16.2 15.0 12.6 16.4 38.6 44.2 39.1 40.2 33.0 32.7 8.8 21.5 28.8 23.8 27.5 21.1 16.9 25.7 11.5 48.5 71.3 25.3 67.1 39.7 39.7 32.0 50.5 29.3 41.3 19.9 27.6 26.4 21.0 29.3 17.9 56.4 53.4 35.5 37.2 17.1 36.0 20.3 38.6 29.1 18.8 12.7 42.6 14.1 24.7 20.3 51.8 16.9 24.7 30.7 22.2 20.8 89.0 26.7 26.0 69.8 24.3 16.2 40.2 36.6 27.6 34.6 24.0 19.1 22.3 30.9 26.4 12.1 18.5 1.7 2.3 3.0 2.5 1.9 3.6 2.8 3.0 2.7 2.6 2.1 3.0 2.8 6.4 2.5 2.5 2.1 2.8 1.5 11.9 13.9 12.7 12.8 14.3 13.2 12.2 13.1 13.8 12.5 12.8 16.4 38.1 41.7 35.1 48.0 42.6 48.3 30.8 29.6 55.2 38.1 41.3 29.5 83.5 54.3 37.9 27.6 37.5 39.6 46.3 58.5 7.9 28.4 14.9 85.5 56.9 43.6 26.9 41.0 84.9 26.5 25.4 41.4 41.8 136.9 25.9 58.3 45.7 62.8 32.6 37.0 86.0 39.1 18.3 47.8 42.1 15.4 33.2 55.5 33.8 67.5 44.6 31.3 30.9 74.9 108.0 32.6 40.1 49.2 38.8 35.6 47.7 21.5 35.8 31.2 32.9 70.6 48.3 86.4 82.9 55.2 55.3 46.7 42.4 45.8 38.0 40.2 UTP14C "2700066J21Rik, KIAA0266" ENSG00000253797 "UTP14C small subunit processome component" Q5TAP6 13 52024691-52033600 "Predicted intracellular proteins" "Differentiation, Meiosis, Ribosome biogenesis, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.2;JURKAT: 2.2;MOLT-4: 1.3;NB-4: 5.7;RPTEC TERT1: 2.1;THP-1: 2.9" "HPA047217, HPA054023" Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoli Cytosol "HPA047217: AB_2679987, HPA054023: AB_2682346" "unprognostic (7.89e-2)" "unprognostic (5.98e-2)" "unprognostic (4.47e-1)" "unprognostic (1.25e-1)" "unprognostic (2.33e-3)" "unprognostic (2.51e-1)" "unprognostic (2.02e-1)" "unprognostic (3.30e-1)" "unprognostic (7.16e-2)" "prognostic unfavorable (7.52e-4)" "unprognostic (7.35e-2)" "unprognostic (1.23e-1)" "prognostic favorable (1.46e-5)" "unprognostic (2.44e-2)" "unprognostic (3.43e-1)" "unprognostic (1.74e-1)" "unprognostic (3.04e-2)" 5.7 5.2 3.8 0.0 3.5 0.0 5.2 3.6 4.4 5.9 4.0 6.1 0.3 7.1 0.0 4.4 5.9 0.0 6.2 3.4 3.5 5.9 7.7 4.7 0.6 3.3 3.9 5.5 6.8 1.2 5.5 0.0 3.3 5.3 0.0 2.2 6.6 0.0 6.7 3.7 5.6 0.2 3.3 5.1 5.9 3.2 3.7 1.8 6.1 2.4 0.0 5.5 5.1 3.8 0.0 0.0 1.2 1.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.2 0.0 0.0 0.0 0.2 1.3 5.7 0.0 0.0 0.0 0.5 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 3.5 3.6 4.4 3.4 3.5 3.3 3.9 3.3 3.3 3.7 3.8 9.9 6.4 17.5 8.5 8.2 5.9 5.6 10.8 9.6 13.9 13.7 7.9 23.8 12.8 15.8 16.5 4.2 10.1 5.1 21.2 0.0 7.3 0.4 9.1 13.9 13.9 18.6 19.9 8.9 7.6 9.6 13.9 5.1 12.4 11.4 14.4 14.6 33.6 9.3 25.2 9.0 14.7 8.2 13.5 3.9 0.8 10.5 8.1 8.8 5.6 8.2 14.1 10.3 6.6 10.7 7.7 11.3 14.3 8.4 12.7 9.9 6.4 14.8 11.6 6.6 20.2 12.6 7.2 13.3 14.0 8.4 7.0 7.2 9.4 14.1 6.7 VAV1 VAV ENSG00000141968 "Vav guanine nucleotide exchange factor 1" P15498 19 6772708-6857366 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 54.1;lymphoid tissue: 46.4" "Cell type enhanced" "Detected in many" "B-cells: 30.7;dendritic cells: 31.3;granulocytes: 34.9;Hofbauer cells: 50.6;Kupffer cells: 29.4;Macrophages: 33.9;Microglial cells: 30.9;T-cells: 26.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 100.7;Karpas-707: 114.7;MOLT-4: 115.8;REH: 76.1;THP-1: 88.9;U-266/84: 89.5;U-937: 95.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001864, HPA005925" Enhanced Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" Cytosol "HPA001864: AB_1858722, HPA005925: " "unprognostic (2.93e-1)" "unprognostic (1.96e-1)" "unprognostic (1.80e-1)" "unprognostic (1.01e-1)" "unprognostic (6.82e-2)" "unprognostic (1.13e-2)" "unprognostic (5.62e-1)" "unprognostic (1.97e-1)" "unprognostic (1.30e-2)" "unprognostic (1.90e-2)" "unprognostic (3.56e-2)" "unprognostic (8.58e-2)" "prognostic unfavorable (1.48e-4)" "unprognostic (9.55e-2)" "unprognostic (1.78e-1)" "unprognostic (6.57e-2)" "unprognostic (3.28e-1)" 6.6 3.8 3.3 36.3 3.3 54.1 2.7 3.6 4.6 2.6 4.5 6.5 5.8 1.8 1.4 3.7 2.4 6.3 1.9 3.3 4.4 2.1 5.0 11.5 46.4 6.2 4.9 1.1 1.3 4.2 1.6 8.7 5.6 2.8 7.1 0.2 6.1 2.3 1.0 1.7 14.1 5.3 5.0 44.9 5.5 1.8 5.7 45.7 2.0 2.1 39.1 13.0 1.7 7.6 1.6 2.2 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 12.7 51.0 16.5 0.0 0.0 0.2 0.0 0.0 0.0 22.0 1.8 61.8 0.0 0.0 0.0 60.7 100.7 0.0 0.0 0.0 0.0 0.0 0.0 63.9 2.3 114.7 0.0 9.6 115.8 36.6 0.0 0.0 0.0 76.1 0.0 41.0 2.2 0.0 0.0 0.0 0.0 18.3 0.1 0.0 8.0 88.9 0.2 0.0 1.6 0.1 0.1 69.9 89.5 57.9 0.1 95.3 0.0 1.6 18.3 20.0 22.0 30.3 15.7 14.3 16.1 19.3 16.6 13.6 17.2 15.6 40.6 19.2 39.8 14.4 14.5 18.2 3.3 3.3 3.6 4.6 3.3 4.4 6.2 4.9 5.6 5.0 5.7 7.6 0.5 3.2 3.0 0.0 30.7 1.3 0.8 3.7 0.0 0.5 0.4 0.4 1.1 0.0 6.9 0.0 0.0 0.8 31.3 1.5 0.0 4.2 5.4 5.3 0.3 1.5 1.2 9.9 1.9 0.4 0.7 1.2 1.1 1.1 34.9 0.0 1.8 0.3 50.6 0.0 1.5 1.0 8.2 29.4 19.6 2.2 0.0 33.9 1.8 30.9 18.8 0.0 22.6 0.5 1.2 9.9 6.1 0.0 21.6 0.3 0.0 0.2 11.9 0.0 0.0 0.3 1.2 1.7 1.4 0.3 0.9 1.4 26.5 0.3 2.4 0.6 VIP ENSG00000146469 "Vasoactive intestinal peptide" P01282 6 152750797-152759765 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 72.2;lymphoid tissue: 155.5" "Group enriched" "Detected in some" 5 "Inhibitory neurons: 80.6;Melanocytes: 28.4" "Group enriched" "Detected in some" 6 "colorectal cancer: 3.7;pancreatic cancer: 4.3;stomach cancer: 2.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SH-SY5Y: 2.7;TIME: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA017324, CAB018649, HPA072701, CAB079780" Supported Supported Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 122000 "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "CAB018649: AB_2304501, CAB079780: , HPA017324: AB_1858754, HPA072701: AB_2686550" "unprognostic (9.58e-2)" "unprognostic (2.29e-2)" "unprognostic (2.60e-2)" "unprognostic (1.13e-1)" "unprognostic (3.34e-2)" "unprognostic (3.33e-2)" "unprognostic (2.48e-2)" "unprognostic (7.21e-2)" "unprognostic (2.22e-2)" "unprognostic (2.89e-2)" "unprognostic (2.36e-1)" "unprognostic (3.62e-1)" "unprognostic (2.92e-3)" "unprognostic (7.47e-2)" "unprognostic (1.94e-1)" "unprognostic (1.30e-1)" "unprognostic (5.90e-2)" 2.7 12.2 5.5 155.5 7.9 0.1 1.9 4.9 10.9 1.8 4.6 72.2 16.6 1.2 0.4 4.3 1.5 3.7 4.3 7.3 28.7 2.5 1.1 3.4 0.4 6.9 40.0 0.8 8.3 0.3 0.8 0.6 7.7 2.7 61.4 1.0 0.5 0.5 1.4 0.4 45.8 41.6 4.8 9.7 22.2 1.0 11.9 0.1 2.3 1.7 0.1 1.6 9.4 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 7.9 4.9 10.9 7.3 28.7 6.9 40.0 7.7 4.8 11.9 5.9 2.5 0.0 0.0 3.3 0.2 0.4 0.0 0.0 0.0 1.3 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 2.8 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 80.6 0.0 0.0 0.3 0.0 6.5 0.0 0.0 28.4 4.7 0.0 0.0 0.0 2.5 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 VKORC1L1 ENSG00000196715 "Vitamin K epoxide reductase complex subunit 1 like 1" Q8N0U8 7 65873074-65959563 "Enzymes, FDA approved drug targets, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053954 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum" "HPA053954: AB_2682319" "unprognostic (3.01e-1)" "unprognostic (1.76e-3)" "unprognostic (4.64e-2)" "unprognostic (4.65e-2)" "unprognostic (3.00e-3)" "unprognostic (7.15e-3)" "unprognostic (1.30e-3)" "unprognostic (8.84e-3)" "unprognostic (5.12e-2)" "unprognostic (5.59e-2)" "unprognostic (9.23e-3)" "unprognostic (1.07e-1)" "unprognostic (1.59e-2)" "unprognostic (1.17e-1)" "unprognostic (7.03e-3)" "unprognostic (4.30e-1)" "unprognostic (5.06e-2)" 54.0 11.1 8.1 11.2 9.0 4.3 23.7 8.3 12.1 12.0 3.7 12.4 11.1 12.3 10.6 12.5 10.0 10.0 12.1 10.1 9.2 10.0 22.9 18.4 8.7 18.1 10.5 17.3 9.7 33.6 6.7 12.0 10.5 12.0 12.5 11.5 10.9 12.4 21.6 12.8 11.6 11.6 8.9 7.4 12.8 9.1 8.5 9.7 13.9 15.3 8.7 11.9 9.6 9.6 46.8 29.5 23.4 29.5 72.6 28.6 42.3 49.5 31.8 29.0 29.1 28.7 44.9 40.4 39.0 35.7 43.9 31.2 33.6 20.1 47.9 25.5 33.1 27.6 25.4 24.7 35.4 38.7 20.3 23.2 25.3 29.5 40.7 22.5 29.2 22.6 59.0 30.0 34.9 18.3 31.8 44.8 56.1 43.8 22.0 34.5 34.0 50.5 28.0 18.5 28.0 39.8 38.3 68.5 21.8 32.8 34.5 29.5 33.3 46.6 32.0 29.5 51.0 26.9 47.1 46.1 28.6 43.0 41.6 2.0 1.1 2.7 1.2 1.1 1.0 1.3 1.5 1.4 1.3 1.1 0.9 0.9 1.3 2.9 2.2 3.5 1.5 0.7 8.1 9.0 8.3 12.1 10.1 9.2 18.1 10.5 10.5 8.9 8.5 9.6 19.5 73.7 41.7 16.6 5.5 24.9 18.6 16.2 9.6 21.8 18.6 15.9 21.5 27.1 24.2 16.5 12.5 12.5 10.0 27.1 5.9 18.1 39.0 13.7 23.8 17.1 13.8 26.1 42.7 24.8 21.2 22.6 19.4 25.3 5.1 24.1 10.8 46.9 16.0 30.3 36.6 26.4 20.3 6.6 10.2 9.1 17.7 12.9 7.2 28.1 10.0 11.6 7.2 26.7 34.6 31.6 8.2 18.4 15.6 36.3 14.4 11.4 11.7 20.2 6.6 24.9 26.4 18.5 7.2 17.9 32.0 8.8 6.6 10.8 20.3 22.6 VNN2 "FOAP-4, GPI-80" ENSG00000112303 "Vanin 2" O95498 6 132743870-132763459 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.6;lymphoid tissue: 56.6" "Cell type enhanced" "Detected in many" "Ductal cells: 63.6;Ionocytes: 22.4;Macrophages: 41.1;monocytes: 57.5;Respiratory ciliated cells: 25.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 7 "neutrophil: 477.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 477.4" "Cell line enriched" "Detected in some" 7 "Daudi: 59.7" "Low region specificity" "Detected in some" NA NA 240000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (2.13e-1)" "unprognostic (1.15e-1)" "unprognostic (9.60e-3)" "unprognostic (5.71e-2)" "unprognostic (2.14e-1)" "unprognostic (5.61e-3)" "unprognostic (1.98e-3)" "unprognostic (4.38e-1)" "unprognostic (3.07e-1)" "unprognostic (3.46e-1)" "unprognostic (2.84e-1)" "unprognostic (8.30e-2)" "prognostic unfavorable (2.72e-7)" "unprognostic (1.62e-1)" "unprognostic (8.17e-2)" "unprognostic (2.01e-1)" "unprognostic (5.45e-2)" 21.7 2.7 0.6 23.9 0.9 31.6 1.3 0.7 2.8 4.3 1.4 3.8 2.4 1.3 0.4 4.1 5.3 22.5 2.3 0.5 0.7 2.4 10.1 22.5 39.0 1.5 1.0 1.5 4.3 0.7 0.9 20.7 1.7 1.8 3.0 0.1 1.5 0.9 0.6 0.3 4.6 6.3 0.8 56.6 7.3 0.6 1.0 11.7 1.2 7.9 42.0 17.8 1.2 1.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 59.7 1.1 0.0 1.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.9 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 1.1 1.4 0.0 0.0 11.6 65.2 0.3 24.6 14.5 10.3 40.3 8.4 29.0 14.1 32.2 27.0 39.4 477.4 36.1 9.9 2.6 6.1 40.4 0.6 0.9 0.7 2.8 0.5 0.7 1.5 1.0 1.7 0.8 1.0 1.0 0.2 0.0 6.7 0.0 11.0 0.0 0.5 4.3 0.0 0.0 0.2 0.0 1.5 7.2 11.8 0.0 0.0 0.8 10.9 0.1 0.0 63.6 0.0 0.3 0.0 1.4 0.0 1.3 0.2 0.4 0.2 1.9 13.3 0.2 5.1 0.1 3.3 1.0 13.9 0.0 0.0 0.0 22.4 18.6 1.0 0.0 0.0 41.1 0.0 1.9 57.5 0.3 20.6 0.0 0.1 3.6 0.0 0.0 2.7 8.0 0.0 0.6 25.4 0.1 6.6 2.5 1.2 0.1 0.0 0.1 0.0 1.4 10.9 6.5 0.2 14.5 VPS37D "MGC35352, WBSCR24" ENSG00000176428 "VPS37D subunit of ESCRT-I" Q86XT2 7 73667831-73672112 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 13.0;Collecting duct cells: 11.0;Distal tubular cells: 9.8;Muller glia cells: 13.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SH-SY5Y: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040978 Uncertain Approved Vesicles NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA040978: AB_10805833" "unprognostic (2.98e-2)" "unprognostic (2.17e-1)" "unprognostic (1.13e-2)" "unprognostic (7.85e-2)" "unprognostic (1.93e-1)" "unprognostic (3.85e-2)" "unprognostic (2.54e-1)" "unprognostic (3.94e-1)" "unprognostic (8.80e-2)" "unprognostic (1.97e-1)" "prognostic favorable (2.07e-5)" "unprognostic (4.19e-2)" "prognostic favorable (5.80e-9)" "unprognostic (9.63e-2)" "unprognostic (1.67e-1)" "unprognostic (1.25e-2)" "unprognostic (1.43e-1)" 1.8 1.3 8.4 0.3 8.7 0.2 2.4 7.9 12.1 6.1 3.5 3.1 1.8 3.7 2.8 0.8 3.6 1.4 2.3 8.9 7.9 11.3 9.6 1.0 0.2 7.9 7.3 4.2 4.0 2.7 3.3 0.3 8.0 3.7 0.2 1.6 3.2 2.0 1.3 2.5 1.9 0.7 6.3 0.9 2.1 7.1 8.6 0.3 3.4 0.5 0.1 2.2 2.8 7.0 0.5 2.3 1.8 3.8 1.2 2.4 1.1 1.0 1.5 0.8 1.0 0.2 0.7 0.8 0.9 1.3 2.1 0.3 1.9 0.9 0.2 0.3 2.0 0.0 0.2 2.6 3.2 0.0 1.1 1.9 0.5 1.1 0.3 3.5 0.9 3.2 1.1 0.2 1.1 2.8 0.6 0.0 1.2 0.7 3.3 0.1 0.0 0.1 3.0 0.2 3.7 11.8 0.0 1.6 2.3 0.3 3.8 0.1 1.3 2.2 3.0 1.3 0.8 1.4 0.1 1.1 5.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 8.7 7.9 12.1 8.9 7.9 7.9 7.3 8.0 6.3 8.6 7.0 2.4 0.0 0.0 1.3 0.2 1.0 0.8 0.3 0.6 13.0 3.4 3.8 1.8 1.5 0.1 11.0 0.0 0.2 0.1 0.2 9.8 4.0 1.1 3.6 3.1 1.1 4.9 0.0 1.6 0.8 0.4 1.6 0.0 5.1 0.0 5.9 1.8 5.3 0.1 0.0 2.7 0.4 2.0 0.0 0.4 0.9 1.8 0.2 5.4 1.0 0.6 13.9 0.0 1.0 0.9 1.8 1.4 2.6 0.3 1.0 2.0 8.3 0.2 5.3 0.0 0.9 2.7 0.6 8.3 0.1 1.1 0.3 0.2 0.9 0.7 0.4 VSIG2 "CTH, CTXL" ENSG00000019102 "V-set and immunoglobulin domain containing 2" Q96IQ7 11 124747474-124752255 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "stomach 1: 619.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 514.3;Gastric mucus-secreting cells: 623.4;Intestinal goblet cells: 285.6;Pancreatic endocrine cells: 260.2;Paneth cells: 509.9;Undifferentiated cells: 207.0;Urothelial cells: 285.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 87.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 6 "OE19: 429.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035919, HPA050147" Enhanced Approved Nucleoplasm NA NA 78000 "Cluster 39: Non-specific - mRNA processing" "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA035919: AB_10669981, HPA050147: AB_2681032" "unprognostic (1.64e-3)" "unprognostic (1.21e-1)" "unprognostic (1.10e-2)" "unprognostic (1.90e-1)" "unprognostic (2.00e-1)" "unprognostic (2.18e-3)" "unprognostic (2.16e-1)" "unprognostic (2.22e-2)" "unprognostic (3.47e-3)" "unprognostic (2.02e-1)" "unprognostic (6.01e-2)" "unprognostic (2.78e-2)" "unprognostic (2.99e-2)" "unprognostic (2.61e-1)" "unprognostic (1.95e-1)" "unprognostic (1.87e-1)" "unprognostic (1.36e-2)" 6.5 0.8 3.1 7.0 6.4 3.4 9.5 0.8 7.1 29.7 0.2 136.2 6.2 4.9 0.4 26.4 17.5 26.5 5.3 2.8 1.5 6.3 3.0 45.7 0.9 1.7 3.6 1.1 2.0 1.9 1.7 6.0 2.0 58.2 137.8 0.6 31.8 4.3 2.3 1.5 2.8 4.7 1.1 1.6 619.2 0.9 3.1 0.2 43.7 2.5 2.5 84.5 9.3 3.6 0.4 0.1 4.8 3.4 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.9 1.5 2.4 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.3 16.6 0.0 7.9 0.7 0.5 3.0 0.1 0.0 0.0 0.0 0.3 2.8 0.3 0.3 0.6 0.0 1.6 0.1 0.1 0.6 429.0 3.7 0.4 3.6 0.1 0.1 69.2 0.3 0.9 0.1 4.6 0.0 0.7 0.4 2.4 4.1 1.8 1.1 0.3 0.8 0.3 0.0 0.0 0.6 1.7 0.9 0.0 1.2 0.0 0.0 0.1 0.5 0.0 0.5 0.1 0.4 0.0 0.6 0.4 0.1 0.3 0.2 0.0 0.7 0.9 3.1 6.4 0.8 7.1 2.8 1.5 1.7 3.6 2.0 1.1 3.1 3.6 4.6 125.0 51.6 0.0 1.5 0.8 19.2 25.3 2.8 1.5 31.5 18.4 0.7 82.9 99.3 3.7 0.0 0.0 0.6 514.3 1.9 14.6 0.0 12.1 1.8 5.0 66.8 0.0 0.2 90.9 0.1 0.9 623.4 18.3 1.3 0.1 3.9 0.2 0.1 0.0 0.1 285.6 20.3 0.3 2.7 0.0 1.5 2.4 3.6 1.0 0.0 0.0 0.0 0.0 0.1 260.2 509.9 0.0 0.7 61.6 1.3 0.1 36.7 0.0 0.0 0.3 6.2 0.2 0.7 0.7 0.4 0.0 2.2 0.3 207.0 285.3 VSIG4 "CRIg, Z39IG" ENSG00000155659 "V-set and immunoglobulin domain containing 4" Q9Y279 X 66021738-66040125 "Plasma proteins, Predicted membrane proteins" "Complement alternate pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 166.0" "Group enriched" "Detected in many" 5 "Hofbauer cells: 989.8;Kupffer cells: 590.9;Macrophages: 328.4" "Cancer enriched" "Detected in all" 5 "glioma: 88.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "classical monocyte: 18.7;intermediate monocyte: 11.1;myeloid DC: 17.8" "Group enriched" "Detected in many" 31 "dendritic cells: 17.8;monocytes: 18.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003903, CAB026000" Enhanced Uncertain "Nucleoli,Plasma membrane,Cytosol" NA NA 59000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" Nucleoli "CAB026000: , HPA003903: AB_1858776" "unprognostic (6.87e-3)" "unprognostic (4.79e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (3.19e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-2)" "unprognostic (9.37e-3)" "unprognostic (1.24e-1)" "unprognostic (3.10e-1)" "unprognostic (1.37e-3)" "unprognostic (1.06e-1)" "unprognostic (2.77e-1)" "prognostic unfavorable (1.95e-6)" "unprognostic (3.70e-2)" "unprognostic (5.45e-2)" "unprognostic (3.37e-2)" "unprognostic (3.47e-2)" 137.1 68.8 17.9 44.2 18.8 7.8 44.2 17.0 36.6 14.1 21.5 40.9 22.5 15.5 5.3 15.4 66.8 39.6 30.0 18.2 18.3 17.9 51.0 166.0 27.8 25.1 23.6 12.9 14.3 6.8 7.0 139.6 25.8 10.6 31.7 2.2 24.5 9.3 8.2 10.8 43.9 108.3 18.9 69.3 22.9 7.3 37.6 5.4 12.3 12.5 1.8 61.5 11.6 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 18.7 0.1 0.0 11.1 0.0 0.0 0.0 0.2 17.8 0.1 0.0 0.0 0.5 0.0 0.4 0.1 0.0 5.6 17.9 18.8 17.0 36.6 18.2 18.3 25.1 23.6 25.8 18.9 37.6 26.7 1.3 3.2 16.1 0.0 1.2 2.3 0.3 0.0 0.0 0.0 2.6 0.5 1.8 7.2 3.1 0.0 0.0 5.3 0.3 0.0 0.0 0.1 7.9 0.0 0.0 10.4 0.0 0.0 0.0 0.0 4.9 2.7 0.0 0.0 3.8 0.0 5.0 3.2 989.8 0.0 0.0 0.0 0.0 590.9 111.8 16.6 1.5 328.4 3.6 12.2 1.5 0.5 0.0 0.5 0.0 0.0 0.1 0.4 0.3 0.3 0.0 0.1 4.4 0.0 6.6 0.6 2.0 0.3 0.9 0.5 1.7 12.3 1.5 0.0 0.0 0.2 WDR47 KIAA0893 ENSG00000085433 "WD repeat domain 47" O94967 1 108970214-109042113 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 93.6;Suprabasal keratinocytes: 104.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027287, HPA027289" Approved Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 58: Brain - Synaptic function" "Cluster 18: U-2197 - ECM organization" "Cluster 28: Keratinocytes - Keratinization" "Actin filaments" Nucleoplasm "HPA027287: AB_10599416, HPA027289: AB_10601862" "unprognostic (8.55e-2)" "unprognostic (3.36e-2)" "unprognostic (7.51e-2)" "unprognostic (2.44e-1)" "unprognostic (4.90e-1)" "prognostic favorable (9.86e-4)" "unprognostic (4.05e-3)" "unprognostic (2.83e-2)" "unprognostic (2.87e-1)" "unprognostic (3.67e-2)" "unprognostic (2.71e-2)" "unprognostic (1.93e-1)" "unprognostic (8.39e-3)" "unprognostic (7.90e-3)" "unprognostic (9.23e-2)" "unprognostic (2.73e-2)" "unprognostic (8.09e-2)" 7.8 7.1 22.6 5.5 26.6 12.2 6.3 14.1 27.3 8.8 1.5 8.0 3.7 9.3 5.7 14.4 8.5 7.3 8.1 27.7 17.9 7.6 3.5 7.0 5.6 13.4 11.0 7.5 5.9 9.2 5.3 6.5 14.6 7.3 5.3 37.0 5.8 7.0 17.0 22.9 4.5 10.2 10.9 5.7 6.0 22.7 16.7 7.7 6.2 15.3 7.5 7.5 8.9 19.5 15.6 4.7 8.8 10.9 17.0 14.8 4.7 17.4 10.7 11.4 12.7 4.6 2.3 7.0 9.0 16.7 8.4 17.1 12.5 7.6 15.0 13.1 7.0 5.8 9.9 5.3 9.7 9.2 8.3 9.2 12.4 17.9 8.5 13.8 13.7 8.1 3.5 9.5 19.4 9.3 8.9 7.2 3.7 5.0 9.1 12.5 22.3 3.9 19.0 13.3 15.3 14.0 15.2 8.1 12.5 9.4 3.7 9.3 23.5 15.1 7.0 26.7 14.5 6.1 5.4 5.5 17.6 9.0 23.0 18.0 5.4 7.1 3.3 5.7 3.1 2.4 3.1 3.5 5.8 3.4 2.8 2.5 22.0 2.7 5.9 6.3 5.5 2.6 22.6 26.6 14.1 27.3 27.7 17.9 13.4 11.0 14.6 10.9 16.7 19.5 16.5 12.8 6.5 33.3 13.8 93.6 5.1 7.7 62.0 15.3 11.1 12.6 18.9 10.0 8.0 7.3 45.9 2.4 25.1 2.7 5.9 3.5 33.2 20.5 9.3 12.1 3.0 1.7 46.2 0.9 2.1 10.7 8.2 10.4 2.5 5.6 7.1 2.0 4.4 11.8 39.1 1.0 4.1 5.5 28.4 41.4 8.4 13.9 24.9 19.7 6.3 13.2 8.2 15.1 26.5 3.9 0.9 15.1 14.9 2.4 2.4 5.5 18.9 32.3 6.6 13.5 16.5 32.2 28.9 52.1 104.4 4.9 18.9 3.3 2.1 4.1 WDR54 FLJ12953 ENSG00000005448 "WD repeat domain 54" Q9H977 2 74421678-74425755 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 70.2" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 207.0;Late spermatids: 124.6;Respiratory ciliated cells: 395.9;Spermatocytes: 147.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043257, HPA053558" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" "Vesicles, Cytosol" "HPA043257: AB_10795981, HPA053558: AB_2682189" "unprognostic (1.12e-1)" "unprognostic (3.68e-1)" "unprognostic (1.45e-1)" "unprognostic (2.37e-2)" "unprognostic (2.62e-1)" "unprognostic (3.06e-3)" "unprognostic (4.10e-3)" "unprognostic (1.96e-1)" "unprognostic (2.68e-2)" "unprognostic (1.51e-1)" "unprognostic (7.25e-3)" "unprognostic (3.89e-2)" "unprognostic (3.07e-1)" "unprognostic (1.19e-1)" "unprognostic (1.61e-1)" "unprognostic (8.96e-2)" "unprognostic (4.85e-2)" 8.2 8.5 11.0 6.5 11.7 6.7 7.7 8.5 11.2 11.8 17.6 6.7 3.2 10.4 5.6 3.4 70.2 8.4 4.3 11.8 14.2 12.1 1.9 10.7 11.6 10.3 12.5 10.8 6.3 30.0 24.4 6.3 11.2 7.4 4.0 28.0 5.2 9.9 1.3 4.9 7.0 7.7 10.8 12.2 7.0 38.0 11.7 18.5 7.8 1.7 11.2 8.6 6.3 9.9 44.9 78.3 37.9 32.5 14.0 25.7 11.8 22.5 45.8 56.8 52.8 6.9 34.4 39.3 22.5 25.1 34.5 37.6 27.8 100.6 49.8 30.3 16.8 19.4 42.4 4.7 14.3 30.6 15.3 11.6 27.6 58.1 30.3 67.5 30.6 61.6 7.7 45.8 32.4 69.8 48.6 32.3 30.3 10.9 29.8 41.2 44.1 84.4 51.3 22.4 66.4 52.1 17.6 15.9 27.0 11.2 25.6 14.7 15.3 29.2 50.9 32.1 50.7 49.2 26.7 10.1 86.5 18.8 21.6 6.6 8.5 0.6 31.1 11.5 31.4 24.2 35.5 33.7 28.6 22.0 25.1 23.8 0.7 29.1 10.1 46.7 36.8 21.6 11.0 11.7 8.5 11.2 11.8 14.2 10.3 12.5 11.2 10.8 11.7 9.9 20.0 3.2 12.8 1.3 23.1 7.0 20.1 64.1 10.2 48.3 9.4 10.9 1.7 20.0 39.4 23.9 83.4 9.8 30.1 1.5 19.6 28.5 77.8 207.0 18.5 25.1 28.9 5.5 5.6 6.0 14.6 14.3 7.1 9.2 12.7 23.8 30.0 1.9 8.6 32.0 4.1 6.0 38.7 6.9 17.4 124.6 17.1 7.4 12.4 0.0 29.8 51.9 26.8 3.0 2.4 13.6 4.4 22.2 17.5 9.4 0.8 28.4 395.9 112.5 0.0 8.4 30.6 147.9 19.3 1.7 4.8 2.9 30.5 37.2 3.8 13.3 WDR7 "KIAA0541, TRAG" ENSG00000091157 "WD repeat domain 7" Q9Y4E6 18 56651343-57029811 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Astrocytes: 99.6;Excitatory neurons: 268.8;Inhibitory neurons: 223.0;Microglial cells: 111.5;Oligodendrocyte precursor cells: 146.3;Oligodendrocytes: 244.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042074, HPA051057" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Cytosol "HPA042074: AB_2677833, HPA051057: AB_2732563" "unprognostic (1.03e-1)" "unprognostic (1.32e-2)" "unprognostic (1.65e-2)" "unprognostic (1.40e-1)" "unprognostic (3.71e-2)" "unprognostic (3.66e-2)" "unprognostic (1.97e-1)" "unprognostic (3.58e-1)" "unprognostic (7.70e-2)" "unprognostic (9.21e-2)" "unprognostic (2.00e-2)" "unprognostic (5.05e-2)" "prognostic favorable (1.13e-5)" "unprognostic (4.80e-2)" "unprognostic (4.52e-3)" "unprognostic (7.76e-2)" "unprognostic (2.23e-2)" 5.9 7.6 13.2 5.9 14.2 7.2 4.9 7.0 19.8 4.8 3.1 5.4 4.1 4.8 5.3 4.4 4.2 5.3 5.9 16.2 11.1 5.3 7.4 5.0 7.4 14.6 8.8 4.2 4.2 9.2 8.4 4.7 14.7 7.5 4.9 18.8 4.2 5.7 8.2 4.3 4.3 5.6 7.8 6.2 4.9 4.6 9.6 10.3 9.1 9.6 5.8 5.0 4.5 16.0 4.7 7.7 8.7 4.9 13.5 7.8 2.2 9.2 7.8 7.4 8.8 3.1 2.9 13.0 3.6 8.3 6.3 4.9 8.8 7.2 9.2 15.1 5.4 12.3 5.8 2.8 8.1 18.7 15.0 6.7 5.9 9.9 6.6 6.1 9.3 6.1 6.0 17.5 9.3 4.6 13.0 5.5 3.7 2.4 5.1 5.8 6.7 6.3 5.7 8.4 11.3 5.6 6.5 3.1 4.3 7.4 4.9 5.2 8.3 10.5 5.3 3.2 5.0 17.4 14.2 13.9 8.6 9.3 7.2 4.0 3.0 5.5 3.6 4.4 4.5 2.4 4.0 3.7 3.6 2.2 4.2 3.8 2.6 4.6 5.5 1.7 5.2 2.0 13.2 14.2 7.0 19.8 16.2 11.1 14.6 8.8 14.7 7.8 9.6 16.0 8.7 3.2 4.8 99.6 7.5 2.9 1.9 2.3 2.8 24.5 3.4 2.4 12.5 5.7 6.8 0.0 31.3 2.0 7.7 5.8 3.9 3.2 21.0 4.4 6.0 6.6 8.4 8.2 268.8 3.6 1.2 6.3 7.7 3.9 10.8 9.0 9.3 8.9 5.8 26.9 223.0 2.7 0.0 16.2 2.8 7.0 5.6 11.3 0.0 111.5 8.8 7.1 10.3 146.3 244.7 2.6 2.6 8.2 10.1 2.6 4.5 3.2 5.7 26.3 6.6 10.7 5.8 2.0 1.7 5.8 2.4 0.7 9.9 9.3 4.1 1.6 WWC2 "BOMB, FLJ22029" ENSG00000151718 "WW and C2 domain containing 2" Q6AWC2 4 183099257-183320777 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 262.8;Microglial cells: 129.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SiHa: 84.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044005 Uncertain Approved Microtubules NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 39: CACO-2 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Microtubules "HPA044005: AB_10960552" "unprognostic (1.07e-1)" "prognostic unfavorable (8.61e-4)" "unprognostic (7.16e-4)" "unprognostic (1.70e-1)" "unprognostic (2.00e-2)" "unprognostic (4.48e-3)" "unprognostic (2.05e-1)" "unprognostic (3.93e-2)" "unprognostic (4.42e-2)" "unprognostic (1.97e-1)" "unprognostic (9.52e-3)" "unprognostic (2.22e-1)" "prognostic favorable (9.29e-4)" "unprognostic (3.27e-2)" "unprognostic (3.44e-1)" "unprognostic (3.23e-1)" "unprognostic (2.52e-2)" 9.0 5.5 4.7 4.6 5.9 0.6 7.8 5.5 4.4 7.7 10.0 5.0 2.0 8.9 3.3 5.2 6.9 6.9 12.1 4.4 4.4 18.8 19.2 28.2 2.3 7.3 5.8 11.5 12.6 9.7 1.8 14.5 6.3 7.9 2.9 21.3 6.1 8.8 4.2 4.1 2.1 9.9 6.6 6.3 6.8 15.5 5.4 1.0 15.9 5.5 2.2 6.2 3.8 7.7 26.0 10.9 23.1 20.7 16.9 18.8 26.7 34.5 27.1 37.2 26.6 48.2 24.7 0.0 16.9 55.7 13.0 9.2 35.7 14.3 46.9 0.0 11.0 26.3 25.4 24.9 17.5 12.5 27.6 14.3 10.7 24.6 22.9 30.8 25.1 3.7 18.9 1.4 28.6 7.5 0.0 8.3 22.0 0.7 9.3 0.0 21.1 14.0 52.7 6.9 1.5 11.7 84.2 72.7 11.1 36.5 17.6 4.2 37.8 13.8 38.2 8.2 25.1 0.0 0.0 0.3 13.5 5.7 24.7 0.0 0.3 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.4 0.0 0.0 0.0 4.7 5.9 5.5 4.4 4.4 4.4 7.3 5.8 6.3 6.6 5.4 7.7 27.8 262.8 65.4 23.2 0.4 24.0 9.3 6.3 8.6 5.4 15.0 11.4 30.0 37.1 24.0 7.3 64.6 15.4 1.4 0.7 27.4 16.3 36.9 26.7 26.6 27.4 1.2 3.6 62.1 14.6 9.8 25.0 9.2 35.4 19.0 39.5 17.2 39.0 10.5 0.0 98.1 0.2 4.1 15.6 7.7 26.9 17.7 9.0 12.4 129.3 7.6 11.7 0.0 52.3 44.0 30.3 0.1 21.1 0.8 29.3 0.0 24.7 11.5 58.6 26.3 34.2 24.2 41.8 19.7 7.7 15.3 6.6 3.2 19.9 0.4 12.2 WWOX "FOR, SDR41C1, WOX1" ENSG00000186153 "WW domain containing oxidoreductase" Q9NZC7 16 78099430-79212667 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" Oxidoreductase "Disease variant, Epilepsy, Neurodegeneration, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 14 "Astrocytes: 927.8;Excitatory neurons: 270.5;Inhibitory neurons: 540.9;Microglial cells: 471.2;Oligodendrocyte precursor cells: 914.9;Oligodendrocytes: 793.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 85.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050992 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" Cytosol "HPA050992: AB_2681299" "prognostic unfavorable (9.07e-5)" "unprognostic (1.14e-2)" "unprognostic (1.92e-1)" "unprognostic (9.27e-2)" "unprognostic (2.32e-1)" "unprognostic (1.81e-1)" "unprognostic (6.24e-2)" "unprognostic (1.69e-1)" "unprognostic (1.65e-1)" "unprognostic (3.61e-3)" "unprognostic (4.33e-2)" "unprognostic (3.50e-2)" "prognostic favorable (4.49e-5)" "unprognostic (3.75e-1)" "unprognostic (1.78e-1)" "unprognostic (2.36e-2)" "unprognostic (1.77e-1)" 8.6 6.3 18.6 4.0 23.9 4.2 7.4 24.0 20.3 8.6 21.2 5.2 5.3 8.2 10.1 7.7 9.0 7.4 5.2 18.8 22.5 12.7 12.0 5.3 4.6 24.0 22.4 7.6 8.3 12.1 9.8 5.3 25.3 7.7 3.2 6.9 8.5 6.4 3.3 7.1 4.5 5.1 22.0 4.7 6.0 9.3 21.0 9.0 21.8 2.1 6.0 6.7 7.1 30.0 11.1 9.5 9.2 7.7 11.0 5.3 11.1 1.6 3.2 3.7 3.2 7.0 9.6 19.5 8.6 1.5 5.2 10.0 5.1 1.3 2.6 11.0 26.8 6.0 1.9 15.7 7.5 16.7 3.4 5.9 3.8 2.3 2.4 0.9 4.4 25.9 9.2 4.2 2.6 85.7 27.7 21.9 8.6 5.9 5.7 32.2 3.9 19.1 5.3 3.9 17.6 10.0 7.1 11.9 4.0 9.3 12.8 12.0 1.6 2.7 10.4 2.2 6.4 0.0 18.3 41.2 10.4 8.4 4.6 7.0 9.1 2.1 11.4 7.9 13.4 9.3 8.2 9.1 7.7 6.6 8.4 8.3 0.7 9.1 5.8 14.5 13.5 6.0 18.6 23.9 24.0 20.3 18.8 22.5 24.0 22.4 25.3 22.0 21.0 30.0 12.0 6.4 6.9 927.8 9.0 9.2 21.2 8.0 19.4 7.4 12.1 16.1 8.8 17.2 13.3 14.7 4.2 25.7 10.9 4.5 33.2 12.4 43.1 18.2 13.9 9.5 9.6 13.3 270.5 10.3 11.9 12.0 9.2 7.6 12.7 18.7 13.2 18.9 9.2 5.0 540.9 5.1 0.0 5.6 5.7 38.2 14.0 7.7 5.4 471.2 5.9 46.3 9.2 914.9 793.5 4.5 5.9 17.7 18.4 11.5 8.7 28.3 18.7 12.2 6.6 10.3 11.8 19.7 17.9 13.3 6.8 17.4 9.9 12.1 6.8 13.0 WWP1 "AIP5, DKFZP434D2111" ENSG00000123124 "WW domain containing E3 ubiquitin protein ligase 1" Q9H0M0 8 86342547-86478420 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 171.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023180 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Golgi apparatus, Plasma membrane" "HPA023180: AB_10602587" "unprognostic (3.89e-1)" "unprognostic (6.63e-2)" "unprognostic (3.81e-2)" "unprognostic (7.91e-2)" "unprognostic (3.70e-1)" "unprognostic (1.02e-1)" "unprognostic (1.93e-1)" "unprognostic (4.24e-2)" "unprognostic (1.83e-1)" "unprognostic (9.43e-3)" "unprognostic (3.09e-3)" "unprognostic (1.48e-1)" "prognostic favorable (5.45e-5)" "unprognostic (2.35e-1)" "unprognostic (4.63e-1)" "unprognostic (3.19e-3)" "unprognostic (1.01e-1)" 33.6 22.1 16.3 25.8 21.5 18.2 40.6 19.6 16.3 23.6 24.3 26.9 26.3 23.0 24.6 33.1 18.5 45.3 50.8 14.3 20.7 40.9 111.7 27.2 39.0 18.3 19.0 24.7 28.0 116.3 9.8 36.9 19.7 33.4 33.1 43.2 25.9 25.6 171.4 40.8 28.1 24.6 18.1 45.7 34.3 29.5 19.5 22.7 32.6 122.2 30.6 33.7 15.8 23.1 59.8 27.1 18.3 13.1 23.0 22.4 16.3 21.0 22.5 16.5 19.5 18.9 35.3 24.9 14.0 36.5 22.9 49.3 26.4 34.1 28.5 31.6 21.0 28.7 24.4 44.7 16.8 11.7 14.0 20.5 42.5 18.2 33.3 25.3 74.1 29.0 14.3 28.7 28.4 29.6 27.7 8.1 11.2 82.6 30.0 18.0 21.4 22.5 37.3 44.5 5.5 12.9 21.2 104.7 23.0 39.8 31.3 10.8 84.4 23.9 28.7 26.3 10.7 33.9 22.0 25.7 29.9 1.6 19.0 6.2 2.1 3.9 5.2 1.9 4.6 2.7 6.4 5.3 1.5 2.4 7.5 4.7 1.3 2.4 2.2 1.9 6.5 2.0 16.3 21.5 19.6 16.3 14.3 20.7 18.3 19.0 19.7 18.1 19.5 23.1 51.2 25.6 22.6 29.0 13.0 35.8 26.9 15.4 26.7 28.8 41.7 23.5 82.7 44.3 19.2 29.5 58.4 28.3 19.5 23.7 43.0 20.5 42.1 22.6 20.1 32.3 23.6 3.0 55.3 37.6 3.3 27.6 35.2 35.5 3.8 18.0 62.4 88.8 55.9 40.4 134.6 25.3 14.2 95.2 28.1 12.7 32.3 43.0 30.2 61.8 18.6 23.3 18.6 60.3 103.8 45.1 16.0 36.5 18.5 45.1 15.8 45.7 17.2 52.6 6.6 18.8 16.6 12.4 21.2 28.8 39.5 23.0 32.0 25.1 19.7 38.3 XBP1 XBP2 ENSG00000100219 "X-box binding protein 1" P17861 22 28794555-28800597 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Angiogenesis, Apoptosis, Autophagy, Differentiation, Lipid biosynthesis, Lipid metabolism, Myogenesis, Protein transport, Stress response, Transcription, Transcription regulation, Transport, Unfolded protein response" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 1159.0" "Cell type enhanced" "Detected in all" "Breast glandular cells: 1756.7;Plasma cells: 2344.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 960.5;SK-BR-3: 870.0;T-47d: 1012.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" 100.3 103.7 23.8 150.1 25.9 247.2 720.6 26.8 27.7 369.7 46.8 203.6 163.7 94.2 150.5 85.2 126.5 120.2 75.8 22.5 32.2 87.7 687.3 151.8 138.3 33.3 33.2 67.5 1159.0 195.1 87.7 107.9 29.0 228.8 196.5 21.1 849.4 152.1 90.1 72.2 140.3 105.5 30.8 213.2 259.9 22.2 33.0 148.2 168.9 48.7 307.8 250.4 52.2 30.8 77.1 50.8 71.4 111.0 132.2 144.2 181.1 130.9 223.2 128.4 168.8 82.5 104.4 290.2 63.0 121.8 75.3 104.5 134.2 64.4 110.4 130.0 84.9 88.3 42.6 356.2 285.9 166.1 80.8 90.7 378.2 85.2 363.7 115.9 104.1 35.0 79.5 355.0 78.6 960.5 23.3 157.0 49.7 594.6 79.0 168.6 78.5 401.5 118.4 105.4 94.7 90.7 79.0 870.0 358.6 94.8 1012.9 188.5 59.8 73.3 69.8 78.5 47.3 598.8 456.8 174.8 98.0 210.0 112.3 185.0 27.1 23.5 73.3 14.1 95.2 38.0 52.4 76.5 23.5 43.8 52.9 43.2 2.1 88.5 10.1 75.0 20.5 38.5 23.8 25.9 26.8 27.7 22.5 32.2 33.3 33.2 29.0 30.8 33.0 30.8 116.4 86.6 195.6 3.6 379.0 210.6 410.2 192.2 47.3 25.4 1756.7 829.4 46.2 205.9 390.1 138.0 131.3 112.8 298.6 171.2 80.3 240.6 30.2 160.1 147.8 107.0 189.7 68.6 8.5 633.3 335.4 220.0 208.0 293.6 99.7 55.1 93.1 654.5 267.9 15.2 11.4 633.0 225.9 130.0 281.5 22.7 95.7 172.3 355.8 18.7 95.0 18.6 385.2 8.0 7.3 328.4 190.5 64.7 2344.9 381.9 247.0 73.2 168.9 53.2 13.1 144.4 179.3 36.8 32.5 86.2 202.0 349.7 206.1 34.8 260.0 355.3 XCL1 "ATAC, LPTN, LTN, SCM-1, SCM-1a, SCYC1" ENSG00000143184 "X-C motif chemokine ligand 1" P47992 1 168576605-168582069 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4.6" "Group enriched" "Detected in many" 4 "dendritic cells: 185.3;T-cells: 213.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 14 "NK-cell: 88.5" "Lineage enriched" "Detected in many" 14 "NK-cells: 88.5" "Cell line enhanced" "Detected in some" "CACO-2: 2.8;Hep G2: 4.1;SCLC-21H: 3.3;SuSa: 6.1;U-266/70: 5.0;U-266/84: 1.9" "Not detected" "Not detected" HPA057725 Approved "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 63: NK-cells & T-cells - Immune response" "HPA057725: AB_2683511" "unprognostic (5.38e-3)" "unprognostic (5.72e-2)" "unprognostic (8.23e-3)" "unprognostic (4.19e-3)" "unprognostic (1.43e-1)" "unprognostic (6.10e-2)" "unprognostic (2.96e-1)" "unprognostic (4.27e-2)" "unprognostic (1.25e-2)" "unprognostic (2.34e-2)" "unprognostic (4.61e-1)" "unprognostic (8.85e-2)" "unprognostic (5.34e-10)" "unprognostic (1.96e-1)" "unprognostic (1.32e-1)" "unprognostic (5.47e-2)" "unprognostic (2.15e-2)" 0.5 0.1 0.1 1.0 0.1 3.5 1.0 0.0 0.2 1.0 0.0 0.7 1.0 2.2 0.8 0.2 0.6 1.1 0.5 0.1 0.2 0.5 2.6 1.8 2.3 0.1 0.1 0.2 0.5 0.0 0.1 2.2 0.2 0.4 1.0 0.0 1.5 0.3 0.1 0.1 1.5 0.3 0.1 4.6 1.2 0.2 0.6 4.1 0.3 0.0 1.6 0.9 0.4 0.1 0.9 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 3.3 0.0 0.3 0.0 0.0 6.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 5.0 1.9 0.0 0.0 0.0 0.0 3.2 0.0 0.0 6.2 0.0 0.2 0.0 1.0 5.9 0.0 0.0 0.3 4.0 0.3 88.5 0.0 0.0 0.0 1.7 0.1 0.1 0.0 0.2 0.1 0.2 0.1 0.1 0.2 0.1 0.6 0.1 2.3 3.2 5.5 0.0 1.5 4.0 0.5 0.0 2.2 0.0 1.3 1.5 2.0 1.5 0.0 0.0 0.0 1.4 185.3 0.7 0.0 0.0 1.3 2.0 1.9 1.9 0.0 8.4 0.0 0.2 1.2 1.9 8.2 2.9 2.5 0.0 1.4 0.9 0.4 0.0 0.1 0.8 0.0 1.9 10.6 0.0 0.0 3.1 39.2 0.0 0.1 0.0 42.2 0.0 0.0 0.0 0.0 0.0 7.6 0.1 0.0 0.1 0.0 0.0 0.0 0.3 1.7 0.2 0.2 1.8 4.3 0.8 213.4 0.0 0.4 0.1 XYLB "FLJ10343, FLJ12539" ENSG00000093217 Xylulokinase O75191 3 38346760-38421348 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Xylose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 33.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 39.3;Hepatocytes: 49.3;Inhibitory neurons: 35.9;Proximal tubular cells: 31.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 5.4" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA037863, HPA038415" Uncertain Approved "Nuclear speckles" NA NA 12000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA037863: AB_10672729, HPA038415: AB_10672592" "unprognostic (2.48e-1)" "unprognostic (9.72e-2)" "unprognostic (3.42e-2)" "unprognostic (6.25e-2)" "unprognostic (7.52e-2)" "unprognostic (5.19e-2)" "unprognostic (5.82e-2)" "unprognostic (1.26e-3)" "unprognostic (6.55e-2)" "unprognostic (2.22e-1)" "unprognostic (6.91e-3)" "unprognostic (4.63e-2)" "prognostic favorable (8.57e-4)" "unprognostic (3.26e-1)" "unprognostic (2.06e-1)" "unprognostic (5.78e-2)" "unprognostic (3.37e-2)" 1.4 2.3 1.3 1.5 1.0 2.2 3.0 5.4 2.0 1.6 0.0 4.1 5.8 1.9 0.8 1.9 1.1 1.6 0.5 0.9 0.7 11.4 33.4 0.7 1.0 0.9 0.2 2.2 2.5 1.1 0.8 0.9 1.1 1.6 4.6 2.1 5.3 0.9 0.6 1.5 6.4 1.4 0.0 1.0 3.5 1.0 0.9 1.6 0.7 0.5 0.8 1.2 1.3 0.6 3.5 6.4 2.8 6.7 4.2 4.3 6.3 5.9 2.0 4.5 4.4 8.2 3.6 3.7 1.4 7.6 5.4 2.5 8.1 2.5 5.6 5.0 6.2 7.5 5.0 24.1 2.2 10.1 7.7 3.0 5.2 5.8 2.7 1.9 4.7 8.5 18.0 6.2 5.0 2.4 8.3 1.4 3.8 8.9 7.9 4.2 5.5 5.0 0.6 6.3 3.6 3.2 3.7 16.0 12.7 2.4 7.2 6.1 2.6 9.0 7.3 15.6 2.5 3.5 6.6 8.5 5.4 9.1 7.2 1.4 0.9 2.0 0.6 1.6 0.5 0.2 0.5 0.3 1.7 0.3 0.6 0.6 1.9 0.5 1.4 0.6 1.5 0.4 1.3 1.0 5.4 2.0 0.9 0.7 0.9 0.2 1.1 0.0 0.9 0.6 1.0 0.0 1.3 14.0 0.9 0.9 2.1 1.8 6.8 3.2 3.0 3.4 1.1 2.8 1.5 0.0 0.0 4.3 1.7 3.8 1.9 1.0 0.5 0.4 3.5 1.8 0.0 3.4 39.3 3.0 3.8 2.3 8.6 1.0 0.0 1.3 1.1 49.3 4.0 0.0 35.9 5.7 2.0 1.0 3.7 1.0 1.5 2.0 0.0 17.8 1.0 0.4 0.0 17.1 17.7 1.3 5.8 1.9 1.6 1.7 13.0 31.7 1.3 5.1 0.0 2.4 1.4 0.5 2.7 4.1 0.9 1.4 0.8 1.8 5.1 2.1 YEATS2 "FLJ10201, FLJ12841, FLJ13308, KIAA1197" ENSG00000163872 "YEATS domain containing 2" Q9ULM3 3 183697797-183812624 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Epilepsy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 95.6;Inhibitory neurons: 62.1;Oligodendrocyte precursor cells: 71.9;Oligodendrocytes: 80.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045891 Uncertain Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA045891: AB_10961271" "unprognostic (1.57e-2)" "unprognostic (1.10e-1)" "unprognostic (3.56e-2)" "unprognostic (3.40e-3)" "unprognostic (1.14e-1)" "unprognostic (7.49e-2)" "prognostic unfavorable (4.82e-6)" "unprognostic (2.44e-1)" "unprognostic (3.91e-2)" "unprognostic (1.32e-1)" "unprognostic (8.33e-3)" "unprognostic (1.65e-3)" "prognostic unfavorable (6.90e-9)" "unprognostic (1.66e-1)" "unprognostic (1.53e-1)" "unprognostic (1.21e-1)" "unprognostic (2.08e-2)" 7.4 4.8 5.4 8.9 7.4 14.5 7.9 8.1 8.8 8.5 0.0 9.1 5.4 9.0 4.7 8.2 10.3 6.5 6.6 6.4 5.2 6.1 3.4 10.0 12.9 2.4 3.7 15.1 5.4 9.9 8.6 11.2 3.0 8.2 6.8 15.6 8.0 7.3 5.5 8.5 7.0 11.9 1.9 8.9 5.8 8.0 4.2 16.9 9.7 4.8 11.8 8.7 8.4 7.0 38.1 11.3 32.4 14.5 15.5 22.8 35.8 22.1 17.0 32.1 37.5 27.8 13.3 34.7 39.8 19.5 49.9 23.9 31.8 21.2 32.7 28.5 18.8 35.0 12.2 13.7 23.9 26.3 19.4 15.6 16.3 23.1 27.8 32.1 33.1 35.2 14.0 28.3 24.5 10.2 38.3 20.2 29.3 13.8 22.0 53.5 30.5 42.0 12.9 16.6 31.3 22.3 16.4 55.4 29.2 27.1 27.5 17.8 28.2 29.5 21.3 15.1 25.0 26.9 22.6 57.6 22.9 25.8 21.3 0.1 4.6 1.2 1.9 2.0 1.3 1.9 1.7 1.4 1.6 1.3 1.3 1.5 8.5 1.3 7.1 2.1 0.7 1.8 5.4 7.4 8.1 8.8 6.4 5.2 2.4 3.7 3.0 1.9 4.2 7.0 13.8 35.3 2.3 41.4 7.0 2.0 3.3 7.0 8.6 19.5 5.6 7.5 10.1 5.7 5.9 5.5 10.4 4.8 7.4 4.4 0.0 5.7 2.4 10.5 18.3 15.3 8.5 6.3 95.6 4.0 9.7 9.2 7.1 9.8 7.0 42.1 7.5 3.0 7.1 13.5 62.1 6.0 6.1 8.7 6.7 3.3 9.9 10.1 1.8 40.3 6.6 5.8 5.2 71.9 80.0 7.1 3.1 9.4 9.5 5.3 4.7 1.0 11.2 15.8 0.0 10.1 10.4 3.1 12.3 8.7 3.4 2.1 8.8 9.7 4.8 2.8 ZBTB40 "KIAA0478, ZNF923" ENSG00000184677 "Zinc finger and BTB domain containing 40" Q9NUA8 1 22428838-22531157 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042386 Approved Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA042386: AB_10794649" "unprognostic (2.78e-1)" "unprognostic (3.39e-1)" "unprognostic (2.29e-1)" "unprognostic (5.17e-2)" "unprognostic (6.91e-2)" "prognostic favorable (2.01e-4)" "prognostic unfavorable (7.78e-8)" "unprognostic (8.11e-2)" "unprognostic (1.64e-2)" "unprognostic (2.44e-2)" "prognostic favorable (4.12e-5)" "unprognostic (1.52e-1)" "unprognostic (6.74e-2)" "unprognostic (1.98e-2)" "unprognostic (9.51e-2)" "unprognostic (6.66e-2)" "unprognostic (3.34e-2)" 9.1 15.2 6.7 10.9 8.1 8.9 8.1 7.6 7.0 9.7 10.0 10.0 7.8 9.7 7.1 6.4 10.0 8.5 7.5 6.8 7.2 7.4 6.3 8.6 14.2 8.1 8.4 10.7 12.3 8.8 10.6 5.9 7.8 10.1 8.3 12.5 8.2 7.0 10.4 8.3 14.5 7.0 9.9 17.4 9.9 7.3 7.7 9.9 9.5 7.8 15.0 9.6 6.7 9.9 8.6 10.0 15.7 16.6 11.1 9.7 15.2 7.1 8.2 11.4 12.6 8.9 10.8 10.3 8.9 8.6 8.9 10.6 15.6 7.7 13.5 13.3 13.1 22.1 20.0 10.3 9.6 12.4 20.5 7.9 11.1 14.5 10.9 8.5 9.6 13.7 23.5 0.1 9.0 6.4 8.4 16.1 9.7 7.0 8.0 14.7 11.9 11.5 5.4 9.2 12.7 10.8 14.4 10.4 6.1 10.1 19.1 10.2 12.0 13.3 11.2 14.6 7.3 6.5 9.7 9.8 8.0 15.1 9.6 1.0 0.5 0.3 1.0 1.2 1.3 0.8 0.8 0.8 0.8 1.1 0.8 1.0 0.1 2.9 0.5 0.5 1.4 0.4 6.7 8.1 7.6 7.0 6.8 7.2 8.1 8.4 7.8 9.9 7.7 9.9 7.6 12.8 16.7 12.1 12.2 5.7 3.1 4.2 8.0 15.0 7.0 5.0 11.8 8.6 11.7 1.8 31.3 4.6 11.0 3.6 1.9 5.2 4.6 8.9 10.8 8.0 16.2 3.4 15.0 7.4 4.5 7.0 6.6 6.0 16.4 21.1 4.2 3.4 4.8 11.8 20.1 5.1 8.2 5.7 5.7 6.7 5.9 8.1 14.2 25.3 4.1 5.6 13.4 18.6 24.1 6.4 8.2 6.8 12.4 4.8 4.7 2.6 8.8 22.7 13.1 11.9 9.6 7.2 8.2 6.9 4.1 2.9 13.3 13.5 5.8 3.5 ZC3HAV1L "C7orf39, MGC14289" ENSG00000146858 "Zinc finger CCCH-type containing, antiviral 1 like" Q96H79 7 139025706-139036042 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 5.6;Gastric mucus-secreting cells: 4.6;Microglial cells: 9.4;Oligodendrocyte precursor cells: 5.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 11 "basophil: 10.2" "Lineage enriched" "Detected in single" 11 "granulocytes: 10.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA020386, HPA050741" Uncertain Enhanced Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "HPA020386: AB_2257412, HPA050741: AB_2681224" "unprognostic (1.12e-1)" "prognostic unfavorable (7.35e-4)" "unprognostic (3.07e-2)" "unprognostic (1.50e-1)" "unprognostic (6.99e-2)" "unprognostic (1.31e-1)" "unprognostic (1.62e-2)" "unprognostic (8.51e-2)" "unprognostic (3.34e-3)" "unprognostic (2.07e-1)" "unprognostic (3.44e-2)" "unprognostic (2.00e-2)" "unprognostic (1.49e-3)" "unprognostic (5.04e-2)" "unprognostic (2.88e-1)" "unprognostic (1.84e-2)" "unprognostic (3.08e-3)" 3.1 3.7 2.2 2.6 2.8 1.3 3.4 0.0 2.1 3.3 9.9 2.3 3.2 6.7 2.2 4.3 4.9 3.2 2.6 3.3 3.8 2.8 0.8 2.5 2.5 1.4 1.2 9.3 1.8 2.3 1.6 9.5 0.9 3.9 3.2 0.5 2.6 4.3 1.7 8.7 2.6 5.2 0.6 4.6 2.8 2.0 4.4 2.9 8.3 1.6 3.0 2.7 2.8 1.0 14.9 11.9 8.6 28.8 7.1 10.8 0.4 7.2 3.2 5.3 7.3 19.9 8.4 0.4 10.1 7.8 0.0 10.5 12.1 3.0 16.0 8.8 0.1 19.0 12.6 6.8 5.7 0.1 6.6 8.3 4.6 7.9 3.7 0.3 9.1 9.3 8.3 0.5 10.9 0.1 20.4 11.4 1.5 2.0 7.4 21.1 29.2 0.2 4.9 7.9 5.8 26.1 17.7 2.5 10.6 1.7 10.9 7.7 12.7 9.5 8.5 3.2 0.1 0.5 0.1 0.3 5.3 0.1 9.0 10.2 0.1 0.9 0.1 0.1 0.2 0.4 0.3 0.2 0.1 0.9 0.2 0.2 0.4 0.2 0.1 0.2 0.2 0.2 2.2 2.8 0.0 2.1 3.3 3.8 1.4 1.2 0.9 0.6 4.4 1.0 2.4 0.0 0.0 1.6 0.1 0.4 0.9 0.2 2.8 0.3 0.8 1.7 0.5 0.0 0.1 0.0 0.0 1.2 0.1 0.2 0.0 0.2 0.0 1.4 4.4 1.6 0.0 3.8 5.6 0.0 1.6 2.0 4.6 0.8 4.5 3.0 1.1 0.0 0.9 0.0 2.3 0.0 0.0 0.3 0.3 0.0 1.8 0.5 0.0 9.4 0.0 0.6 0.0 5.5 0.2 0.2 0.0 1.5 1.5 0.6 0.0 0.3 0.1 0.0 0.0 0.9 2.3 0.0 0.6 2.9 1.0 0.7 0.2 3.8 0.2 0.5 ZDHHC13 "FLJ10852, FLJ10941, HIP14L" ENSG00000177054 "Zinc finger DHHC-type palmitoyltransferase 13" Q8IUH4 11 19117099-19176422 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 120.5;Urothelial cells: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 136.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016759, HPA018791" Uncertain Supported "Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "Golgi apparatus" "HPA016759: AB_1858993, HPA018791: AB_1858992" "unprognostic (1.43e-2)" "unprognostic (4.00e-3)" "unprognostic (1.08e-1)" "unprognostic (1.11e-3)" "unprognostic (2.95e-2)" "unprognostic (1.34e-2)" "unprognostic (1.55e-2)" "unprognostic (1.57e-1)" "unprognostic (3.57e-3)" "unprognostic (3.03e-2)" "unprognostic (1.63e-1)" "unprognostic (2.16e-1)" "unprognostic (6.95e-3)" "unprognostic (1.15e-1)" "unprognostic (7.93e-2)" "unprognostic (2.17e-1)" "unprognostic (2.76e-2)" 4.8 5.7 5.2 7.8 5.2 9.7 8.9 6.6 7.1 9.3 6.6 16.9 11.2 6.7 5.1 37.2 12.9 8.7 9.1 5.4 5.7 9.2 2.2 6.1 9.6 5.5 5.0 5.3 11.2 14.9 11.7 6.2 5.8 8.2 18.2 16.1 10.2 5.4 1.6 18.8 11.3 6.1 5.3 5.7 18.5 14.4 5.0 11.7 8.7 2.9 22.4 22.4 15.4 5.2 41.6 19.3 18.0 15.5 6.3 7.2 17.3 19.4 17.8 21.3 24.4 11.7 9.7 21.1 13.1 16.3 47.9 61.3 26.0 12.8 23.3 26.4 22.6 11.1 12.6 9.7 14.6 15.2 18.5 8.3 14.7 9.0 12.5 19.9 136.8 28.9 10.7 10.3 22.1 13.5 19.6 12.2 15.1 38.7 17.6 21.3 25.0 5.0 21.9 27.0 31.3 23.0 23.2 28.0 10.7 17.3 13.2 17.6 39.6 18.9 13.2 29.2 15.8 8.7 28.5 19.2 22.6 15.5 33.6 11.6 4.7 32.7 8.5 7.9 7.8 8.7 6.6 9.6 5.9 5.5 6.2 8.3 6.0 6.3 6.4 5.6 9.4 4.6 5.2 5.2 6.6 7.1 5.4 5.7 5.5 5.0 5.8 5.3 5.0 5.2 8.1 9.6 10.7 28.7 9.6 24.2 22.3 27.2 14.2 12.0 7.5 4.8 34.1 12.8 41.3 16.5 10.4 8.7 10.6 20.1 5.9 25.1 120.5 21.5 6.6 11.3 15.6 11.6 27.2 19.2 18.8 9.2 24.5 30.8 12.0 16.2 12.8 0.9 6.1 16.8 34.9 24.7 36.7 6.8 8.3 46.6 7.8 6.2 3.6 9.4 20.8 52.8 18.6 19.6 20.9 20.4 16.4 2.2 10.4 47.4 15.5 3.5 57.0 8.8 0.0 5.4 7.4 58.1 31.7 21.3 36.2 6.3 11.4 7.7 21.4 103.0 ZDHHC15 "DHHC15, FLJ31812, MRX91" ENSG00000102383 "Zinc finger DHHC-type palmitoyltransferase 15" Q96MV8 X 75368427-75523502 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Acyltransferase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.2;Inhibitory neurons: 17.7;Oligodendrocyte precursor cells: 17.1" "Cancer enhanced" "Detected in some" "glioma: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 3.2;K-562: 2.1;LHCN-M2: 2.2;MOLT-4: 2.4;NTERA-2: 2.0;RH-30: 3.1;RPTEC TERT1: 1.7;SH-SY5Y: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003618, HPA064901" Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" Cytosol "HPA003618: AB_2217686, HPA064901: " "unprognostic (8.28e-2)" "unprognostic (1.73e-1)" "unprognostic (8.05e-2)" "unprognostic (1.62e-5)" "unprognostic (1.64e-2)" "unprognostic (1.00e-1)" "unprognostic (4.00e-4)" "unprognostic (1.96e-2)" "unprognostic (3.19e-1)" "unprognostic (8.70e-2)" "unprognostic (3.77e-3)" "unprognostic (1.40e-1)" "unprognostic (4.78e-13)" "unprognostic (2.60e-3)" "unprognostic (1.17e-2)" "unprognostic (1.09e-1)" "unprognostic (9.67e-4)" 0.8 1.5 1.7 0.3 1.7 0.1 1.6 1.8 1.5 1.6 1.3 1.0 0.2 1.9 1.0 0.8 1.2 0.8 1.7 1.5 2.5 1.5 0.2 1.2 0.3 2.2 2.2 2.5 1.1 1.1 1.1 0.0 2.0 1.1 0.5 1.9 4.5 1.1 0.3 0.7 0.3 1.5 1.8 0.8 0.4 0.6 3.0 0.8 2.0 0.5 0.2 0.7 0.8 2.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 2.1 0.0 2.2 0.0 2.4 0.0 2.0 0.0 0.0 0.0 3.1 0.0 1.7 0.0 0.8 2.6 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.5 0.0 0.4 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.7 1.8 1.5 1.5 2.5 2.2 2.2 2.0 1.8 3.0 2.0 2.9 6.4 3.1 8.5 0.1 4.0 1.6 0.0 3.4 4.2 2.0 1.5 9.5 1.5 1.3 5.5 4.2 0.0 0.3 0.0 0.0 0.7 0.0 0.2 2.9 3.5 1.8 0.4 18.2 0.7 0.0 3.5 0.0 0.3 1.3 2.5 2.2 0.1 0.1 0.0 17.7 0.0 0.0 0.0 4.4 0.2 0.9 0.1 0.0 5.6 0.0 2.2 1.0 17.1 9.1 0.2 0.0 3.8 0.0 0.7 0.0 1.0 0.0 2.3 6.6 5.4 2.5 0.2 0.7 2.2 3.7 0.0 0.5 2.3 0.0 0.6 ZDHHC4 "FLJ10479, ZNF374" ENSG00000136247 "Zinc finger DHHC-type palmitoyltransferase 4" Q9NPG8 7 6577434-6589374 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032124 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA032124: AB_10610699" "unprognostic (1.07e-1)" "prognostic unfavorable (9.35e-4)" "unprognostic (6.82e-2)" "unprognostic (8.36e-2)" "unprognostic (3.66e-1)" "prognostic unfavorable (3.95e-6)" "unprognostic (9.80e-2)" "unprognostic (1.40e-1)" "unprognostic (2.37e-1)" "unprognostic (4.60e-2)" "unprognostic (1.52e-1)" "unprognostic (1.43e-1)" "prognostic favorable (1.18e-7)" "unprognostic (8.75e-2)" "unprognostic (9.41e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (8.94e-4)" 25.9 31.0 17.5 16.2 19.4 18.8 24.3 19.4 18.8 24.4 21.1 38.2 19.1 28.0 34.2 19.5 31.0 23.3 26.5 17.8 21.1 33.6 35.7 21.9 20.6 19.5 20.9 27.6 37.9 33.0 23.9 18.5 20.5 25.3 20.8 19.3 32.2 25.5 54.5 13.5 22.5 24.6 19.1 17.9 32.9 33.8 20.9 18.6 36.8 43.7 19.4 29.2 18.7 19.6 50.7 35.0 11.7 68.8 60.8 41.4 52.4 26.2 6.5 31.2 44.3 44.3 69.7 29.9 40.1 51.3 66.2 44.2 40.8 25.7 33.2 16.8 24.0 31.4 37.8 48.6 47.8 39.8 36.6 45.2 37.6 24.1 0.0 40.8 27.9 51.8 72.4 40.3 43.5 59.2 22.1 39.6 59.4 45.0 28.1 29.4 57.5 40.3 25.9 43.7 26.9 68.7 35.5 11.8 51.7 60.4 43.1 45.8 18.7 40.6 54.9 39.2 39.3 62.1 58.7 66.7 21.6 50.0 56.5 56.3 25.0 44.8 24.1 31.9 24.8 38.8 25.1 27.3 28.1 36.0 31.4 31.1 2.9 28.7 26.5 113.9 24.5 29.3 17.5 19.4 19.4 18.8 17.8 21.1 19.5 20.9 20.5 19.1 20.9 19.6 11.7 38.5 20.1 2.9 23.3 11.3 46.5 63.4 24.5 30.2 42.1 34.7 4.4 57.2 42.4 35.0 10.4 69.0 46.1 12.1 86.1 60.5 3.0 24.1 22.1 14.3 32.4 26.5 4.6 66.4 69.4 26.0 20.9 20.3 10.2 25.9 25.0 47.3 55.3 21.9 5.4 21.2 42.7 36.5 18.2 3.5 18.0 24.8 21.4 2.8 35.3 71.8 28.8 5.0 6.7 54.6 21.4 32.7 34.2 39.5 27.2 71.9 32.5 24.6 13.1 20.9 25.6 70.2 69.7 19.2 9.2 48.8 19.0 40.6 27.5 39.5 ZEB1 "AREB6, BZP, FECD6, NIL-2-A, PPCD3, TCF8, ZEB, Zfhep, Zfhx1a" ENSG00000148516 "Zinc finger E-box binding homeobox 1" P37275 10 31318495-31529814 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 287.8;Excitatory neurons: 276.1;Inhibitory neurons: 261.9;Microglial cells: 479.7;Oligodendrocyte precursor cells: 968.6" "Cancer enhanced" "Detected in all" "glioma: 15.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 113.1;TIME: 87.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027524, CAB058686, CAB079943" Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm Nucleoli "CAB058686: AB_2665569, CAB079943: , HPA027524: AB_1844977" "unprognostic (1.54e-1)" "unprognostic (3.08e-1)" "unprognostic (3.42e-2)" "unprognostic (1.04e-1)" "unprognostic (4.85e-2)" "unprognostic (7.40e-2)" "unprognostic (1.34e-2)" "unprognostic (5.59e-2)" "unprognostic (1.30e-1)" "unprognostic (2.96e-2)" "unprognostic (3.48e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (7.34e-6)" "unprognostic (5.59e-3)" "unprognostic (1.19e-1)" "unprognostic (1.62e-2)" "unprognostic (1.66e-2)" 26.6 8.6 16.4 12.9 16.2 8.6 16.8 14.0 20.1 33.2 9.9 49.2 6.0 38.7 13.4 11.7 18.6 20.0 34.8 15.2 22.8 7.5 10.4 16.0 9.6 21.1 19.2 9.3 3.8 3.4 7.9 17.5 21.2 14.5 12.3 14.8 8.0 26.9 54.4 7.0 11.8 39.9 16.8 8.1 18.1 10.1 18.2 29.9 11.2 60.5 9.7 24.4 16.4 18.5 0.1 11.1 35.1 43.9 58.4 113.1 0.0 32.7 44.9 6.6 9.3 0.2 0.1 11.3 15.6 39.6 9.3 0.0 14.9 0.0 11.8 19.1 7.9 0.0 7.0 6.3 44.4 9.8 0.3 53.4 0.1 19.6 17.6 21.4 54.9 9.5 7.5 14.4 42.7 0.1 33.7 6.2 2.3 0.0 6.6 11.6 66.0 5.1 12.9 0.0 0.9 15.6 11.1 0.0 0.0 7.2 0.0 6.7 87.7 40.8 9.4 10.0 16.7 9.1 6.3 12.8 10.9 0.0 4.2 4.9 0.0 5.4 2.4 0.0 3.2 4.1 3.2 1.7 1.3 3.1 6.8 3.5 8.5 6.6 0.0 3.1 5.0 1.6 16.4 16.2 14.0 20.1 15.2 22.8 21.1 19.2 21.2 16.8 18.2 18.5 104.4 0.0 7.7 212.9 34.6 11.2 3.0 2.0 0.6 42.7 1.4 2.8 106.3 1.5 3.6 1.8 45.9 0.3 22.0 0.0 0.0 2.1 110.1 7.2 287.8 110.6 0.0 12.2 276.1 2.7 0.5 66.1 2.0 6.5 1.3 17.0 49.6 13.4 1.2 10.1 261.9 0.0 0.0 3.8 25.6 141.8 30.7 6.3 26.6 479.7 10.7 7.2 7.2 968.6 7.3 2.5 0.0 102.0 33.2 3.7 0.0 1.6 1.5 43.4 78.9 99.2 74.2 17.4 15.7 1.1 8.7 0.7 36.2 12.0 0.0 3.8 ZEB2 "KIAA0569, SIP-1, SIP1, ZFHX1B" ENSG00000169554 "Zinc finger E-box binding homeobox 2" O60315 2 144364364-144521057 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant, Epilepsy, Hirschsprung disease, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 363.7" "Cell type enhanced" "Detected in many" "Horizontal cells: 662.9;Inhibitory neurons: 539.3;Oligodendrocytes: 1489.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 154.0;THP-1: 181.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003456 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" Nucleoli "Nucleoplasm, Cytosol" "HPA003456: AB_10603840" "unprognostic (1.02e-1)" "unprognostic (2.08e-1)" "unprognostic (1.12e-1)" "unprognostic (2.42e-1)" "unprognostic (4.12e-1)" "unprognostic (4.17e-2)" "unprognostic (3.69e-1)" "unprognostic (3.77e-2)" "unprognostic (5.83e-2)" "unprognostic (7.90e-2)" "unprognostic (1.33e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (6.04e-5)" "unprognostic (1.11e-2)" "unprognostic (1.73e-2)" "unprognostic (7.45e-2)" "unprognostic (1.32e-2)" 61.3 45.2 185.6 56.8 258.3 127.5 29.5 138.3 165.5 52.4 3.0 24.5 21.9 29.6 9.6 27.9 20.3 43.9 45.7 132.5 155.4 18.2 23.3 41.2 43.2 238.3 214.5 70.5 5.7 6.7 3.3 62.1 222.8 18.5 29.9 35.5 9.6 22.7 20.8 12.8 25.9 33.3 183.2 69.4 18.0 16.2 249.6 10.6 13.3 18.8 24.2 46.6 24.1 363.7 1.6 2.0 83.4 0.1 98.9 49.7 0.3 35.1 35.1 38.5 37.1 0.0 0.8 6.6 0.1 37.4 10.6 0.4 14.5 0.1 47.6 37.6 11.2 154.0 6.3 0.2 23.0 26.4 113.2 42.1 0.9 48.9 22.9 33.7 29.4 0.0 43.0 4.1 45.2 0.2 0.4 79.9 12.3 0.0 1.9 44.1 63.5 0.2 0.4 0.6 0.7 22.1 4.2 0.2 97.3 27.5 0.2 181.4 45.9 42.9 0.7 87.5 11.0 47.1 0.3 7.5 66.7 78.4 122.6 27.8 47.7 12.2 21.0 42.6 1.9 9.2 2.7 10.7 27.0 9.4 1.9 7.7 15.2 7.3 43.9 21.5 0.6 19.0 185.6 258.3 138.3 165.5 132.5 155.4 238.3 214.5 222.8 183.2 249.6 363.7 32.6 6.4 19.2 121.8 92.4 24.9 1.2 0.6 3.4 158.6 2.2 4.3 71.0 1.5 10.1 5.5 4.2 1.7 426.2 0.1 1.9 0.7 2.2 2.1 84.7 29.2 0.0 127.0 228.2 0.8 2.0 123.0 13.3 2.5 157.5 99.3 79.2 4.6 144.5 662.9 539.3 0.0 0.0 435.0 276.3 7.2 120.5 435.0 103.2 343.8 233.6 69.3 223.5 381.0 1489.6 0.2 1.1 66.5 132.3 1.8 0.0 10.3 4.0 11.9 184.1 185.0 198.7 2.9 11.3 3.4 19.6 4.7 136.7 108.8 0.4 2.2 ZFYVE9 "MADHIP, PPP1R173, SARA, SMADIP" ENSG00000157077 "Zinc finger FYVE-type containing 9" O95405 1 52142089-52348671 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 131.0;Inhibitory neurons: 162.6;Oligodendrocyte precursor cells: 80.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017702, HPA065852, HPA065862" Approved Enhanced Vesicles,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Cytosol" "CAB017702: AB_1128462, HPA065852: AB_2685568, HPA065862: AB_2685570" "unprognostic (5.05e-2)" "unprognostic (4.78e-2)" "unprognostic (2.58e-2)" "unprognostic (1.51e-1)" "unprognostic (7.15e-2)" "unprognostic (3.87e-1)" "unprognostic (2.87e-3)" "unprognostic (6.11e-2)" "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "unprognostic (2.47e-2)" "unprognostic (5.36e-2)" "unprognostic (1.17e-3)" "unprognostic (2.14e-1)" "unprognostic (3.69e-1)" "unprognostic (1.99e-3)" "unprognostic (1.73e-2)" 9.3 8.2 13.7 3.3 14.5 1.1 11.2 20.5 16.6 12.4 31.1 8.3 5.7 12.0 7.3 9.1 10.0 6.9 7.2 15.5 13.2 12.9 9.2 9.8 2.2 13.0 13.2 16.3 15.0 25.7 8.9 6.3 14.2 11.1 8.2 13.7 9.2 11.1 25.7 10.7 5.5 11.2 10.9 3.6 7.4 13.8 13.5 5.3 16.9 20.2 3.4 8.9 8.6 13.5 17.9 8.3 11.7 15.1 27.5 25.0 19.2 14.2 18.8 16.5 18.8 9.6 1.4 0.0 8.7 20.0 22.7 6.5 20.8 22.5 25.1 0.1 14.6 5.1 9.3 11.4 18.0 4.5 2.9 16.7 24.9 14.2 31.9 20.1 24.0 11.8 8.0 3.2 22.2 3.9 6.5 3.3 15.4 4.7 14.8 5.7 20.1 1.7 9.4 38.5 9.9 10.2 15.9 13.4 18.4 23.2 6.2 5.9 22.3 16.6 6.7 12.8 8.6 4.5 2.9 2.2 11.8 5.4 6.8 1.3 0.0 0.1 0.2 0.0 0.4 0.2 0.3 0.1 0.0 0.1 0.3 0.2 0.2 0.1 0.0 0.1 0.0 0.1 13.7 14.5 20.5 16.6 15.5 13.2 13.0 13.2 14.2 10.9 13.5 13.5 11.5 9.6 5.9 61.7 0.7 5.1 10.0 4.0 10.8 19.9 6.6 5.7 13.6 7.2 9.4 1.8 4.2 5.5 1.1 8.8 7.9 6.4 12.6 6.3 19.1 9.3 17.5 0.0 131.0 7.4 5.3 11.0 23.4 7.9 1.3 16.0 5.0 8.5 0.5 23.5 162.6 8.1 2.0 0.6 1.3 17.3 15.2 0.5 7.2 45.9 0.2 10.0 1.0 80.9 37.5 4.1 7.9 16.6 3.5 7.8 8.2 10.2 2.5 14.3 13.1 20.9 8.3 45.5 46.8 11.7 7.4 2.9 3.8 15.0 6.3 6.4 ZHX1 ENSG00000165156 "Zinc fingers and homeoboxes 1" Q9UKY1 8 123248451-123275541 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 146.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055357 Supported Nucleoplasm No No "Cluster 27: Non-specific - Gene expression" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA055357: AB_2682793" "unprognostic (4.36e-3)" "unprognostic (6.73e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (6.09e-4)" "unprognostic (8.73e-3)" "unprognostic (5.61e-2)" "unprognostic (9.22e-2)" "unprognostic (1.51e-1)" "unprognostic (2.01e-1)" "unprognostic (6.00e-2)" "unprognostic (7.97e-2)" "unprognostic (1.44e-1)" "unprognostic (2.07e-2)" "unprognostic (6.63e-2)" "unprognostic (1.51e-1)" "unprognostic (1.30e-2)" "unprognostic (1.76e-2)" 28.2 14.8 24.5 12.1 24.3 13.5 18.7 27.0 28.1 20.8 21.3 15.6 18.4 17.4 15.2 37.0 18.5 15.1 15.2 23.3 31.9 22.9 39.5 14.4 12.6 25.4 27.7 20.8 17.2 22.8 12.7 14.3 26.5 17.9 14.8 35.0 17.4 18.6 15.5 27.8 19.3 19.2 23.1 15.8 14.8 10.1 24.1 19.8 37.7 19.4 15.0 19.8 17.9 29.4 29.7 13.2 18.0 21.3 34.3 28.3 11.6 35.3 19.6 25.6 29.6 23.5 12.4 44.7 46.1 42.8 11.4 19.6 51.3 32.5 32.4 89.5 26.5 72.6 29.1 14.2 23.3 26.9 33.3 21.4 36.9 35.1 30.0 21.9 20.5 21.2 86.0 34.1 38.3 89.7 62.0 12.1 4.8 62.1 27.7 31.3 16.2 32.0 22.9 66.0 86.3 32.1 40.3 113.6 14.1 10.5 45.4 30.6 19.3 40.1 53.4 32.6 23.8 32.1 95.1 49.6 27.2 49.7 11.2 1.5 3.6 3.6 3.8 6.4 4.8 3.3 4.8 3.5 4.9 3.9 4.5 4.8 1.3 6.5 14.0 2.7 5.7 2.9 24.5 24.3 27.0 28.1 23.3 31.9 25.4 27.7 26.5 23.1 24.1 29.4 35.0 25.6 25.7 0.0 15.7 37.1 28.0 19.7 47.3 46.3 28.8 27.1 30.7 25.8 26.8 20.2 47.9 10.4 22.8 33.5 31.3 16.6 10.9 13.0 52.5 30.8 43.3 19.8 0.0 22.3 6.6 33.0 19.4 13.8 28.5 19.1 28.9 71.5 15.0 146.4 0.0 23.1 14.2 24.2 19.0 21.7 46.6 19.4 26.6 0.0 20.5 46.3 27.8 0.0 0.0 16.7 25.8 64.3 15.3 21.2 35.8 33.2 21.4 34.3 39.5 34.4 38.0 38.5 27.6 84.4 62.5 9.6 20.0 27.0 22.8 29.2 ZNF143 "pHZ-1, SBF, STAF" ENSG00000166478 "Zinc finger protein 143" P52747 11 9460319-9528524 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 59.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003263, HPA003264, HPA074818" Supported Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Nuclear bodies, Golgi apparatus, Vesicles" "HPA003263: AB_1080672, HPA003264: , HPA074818: AB_2686715" "unprognostic (2.30e-2)" "unprognostic (2.12e-2)" "unprognostic (5.51e-2)" "unprognostic (9.72e-2)" "unprognostic (5.09e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.76e-5)" "unprognostic (4.87e-3)" "unprognostic (2.57e-3)" "unprognostic (9.56e-2)" "unprognostic (1.26e-3)" "unprognostic (1.06e-1)" "prognostic unfavorable (6.78e-4)" "unprognostic (1.20e-3)" "unprognostic (1.92e-2)" "unprognostic (1.06e-2)" "unprognostic (7.55e-2)" 9.0 6.1 8.6 11.4 10.1 18.6 9.6 17.3 9.9 10.0 10.8 9.7 9.5 10.5 14.4 9.8 10.1 8.4 9.3 7.9 9.3 8.6 9.6 9.1 15.7 9.9 8.8 13.7 7.7 7.9 7.1 10.4 11.2 8.7 9.9 16.1 8.9 8.0 17.3 10.2 8.2 9.5 9.8 11.1 7.7 16.9 9.0 18.9 14.6 11.5 14.1 11.2 8.4 14.9 20.0 18.8 23.4 15.2 18.9 17.4 21.5 21.8 17.3 16.4 17.9 26.7 24.3 19.6 9.7 17.7 14.0 22.5 23.1 17.3 24.5 20.0 27.7 18.5 27.7 18.7 15.6 25.9 17.8 15.3 20.4 22.2 19.4 21.4 16.3 17.9 20.5 23.3 18.3 17.1 24.1 10.6 26.3 23.0 19.9 21.4 21.2 12.3 14.7 24.0 16.1 15.8 24.0 16.0 14.3 20.6 14.9 14.6 15.6 21.4 15.3 15.1 19.6 11.5 21.6 33.4 13.8 14.8 12.5 39.1 24.6 57.3 28.0 24.9 25.0 23.0 24.6 22.9 20.9 18.2 22.8 19.6 45.1 19.4 28.2 10.1 29.7 19.6 8.6 10.1 17.3 9.9 7.9 9.3 9.9 8.8 11.2 9.8 9.0 14.9 17.9 6.4 12.1 6.2 14.7 26.6 34.1 12.1 17.6 9.3 8.7 13.2 15.5 7.2 10.3 5.5 8.4 10.0 17.1 10.1 3.9 12.5 20.3 18.7 14.9 13.0 6.6 25.4 8.1 11.5 16.2 14.5 9.7 16.3 14.0 7.7 6.8 7.6 9.9 5.0 7.4 6.9 14.2 8.3 22.0 10.0 11.8 15.8 10.6 12.2 16.3 15.5 17.5 7.5 9.8 14.1 7.7 6.8 15.4 20.1 6.3 7.7 15.0 14.3 59.2 18.3 16.7 50.5 21.3 12.8 23.4 18.3 18.1 7.3 7.9 26.9 ZNF407 "FLJ13839, FLJ20307, KIAA1703" ENSG00000215421 "Zinc finger protein 407" Q9C0G0 18 74597870-75065671 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Astrocytes: 96.9;Excitatory neurons: 111.0;Inhibitory neurons: 100.2;Microglial cells: 113.4;Oligodendrocyte precursor cells: 122.6;Oligodendrocytes: 130.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028255, HPA041673" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Plasma membrane" "HPA028255: AB_10603466, HPA041673: AB_2677610" "unprognostic (3.96e-1)" "unprognostic (1.95e-1)" "unprognostic (2.48e-1)" "unprognostic (8.62e-2)" "unprognostic (4.61e-2)" "unprognostic (2.09e-2)" "unprognostic (1.76e-2)" "unprognostic (4.31e-1)" "unprognostic (1.19e-3)" "unprognostic (4.04e-4)" "unprognostic (3.47e-2)" "unprognostic (2.22e-1)" "prognostic favorable (9.79e-5)" "unprognostic (8.87e-2)" "unprognostic (3.07e-1)" "unprognostic (1.24e-1)" "unprognostic (3.11e-2)" 2.4 1.9 2.9 3.1 3.5 5.3 2.9 8.0 2.8 2.7 8.6 2.8 2.2 3.7 1.9 2.5 2.7 2.1 3.2 2.3 2.9 2.4 2.2 2.4 3.3 3.6 3.0 4.8 2.2 3.9 1.5 2.7 4.1 2.8 2.2 2.9 2.4 2.8 3.9 2.3 2.4 3.1 2.9 3.4 2.3 4.0 3.2 5.5 3.6 3.6 3.0 2.4 2.0 4.1 3.9 4.0 4.4 4.1 3.2 4.7 3.2 5.1 4.4 3.7 4.0 1.7 2.2 5.6 1.5 7.1 2.5 4.5 4.2 5.5 5.4 9.3 2.6 7.1 5.5 3.2 2.9 10.9 6.0 4.3 2.4 5.9 5.1 3.5 5.6 3.9 4.1 8.0 5.7 3.1 5.3 1.5 2.6 1.4 3.6 5.4 5.8 4.4 2.6 7.2 4.2 4.0 4.7 2.9 3.6 3.2 3.4 4.6 7.9 8.3 3.5 2.3 4.1 2.8 6.2 5.7 3.0 4.6 5.0 1.6 0.7 0.9 1.0 0.9 1.0 0.8 0.8 0.6 0.3 0.8 0.9 1.1 2.2 1.1 0.6 1.3 0.2 0.4 2.9 3.5 8.0 2.8 2.3 2.9 3.6 3.0 4.1 2.9 3.2 4.1 16.5 6.4 6.3 96.9 10.6 3.2 5.0 3.0 2.8 11.2 6.3 6.0 19.4 2.8 4.9 5.5 6.2 4.2 11.4 6.9 0.0 4.3 4.6 8.6 15.3 10.0 4.2 3.4 111.0 2.9 2.7 7.6 17.3 14.4 1.3 10.2 3.3 5.5 3.2 5.0 100.2 5.7 2.0 5.3 2.8 3.3 5.3 7.6 5.4 113.4 6.1 6.2 8.2 122.6 130.5 4.8 6.0 4.5 11.1 4.4 4.3 2.6 6.2 13.2 6.6 10.8 8.1 9.0 12.8 5.6 4.1 5.2 10.1 12.1 6.0 3.9 ZNF429 ENSG00000197013 "Zinc finger protein 429" Q86V71 19 21496682-21556270 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA004139 Approved Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA004139: AB_2667147" "unprognostic (1.06e-1)" "unprognostic (1.88e-1)" "unprognostic (2.77e-1)" "unprognostic (1.75e-2)" "unprognostic (1.45e-2)" "unprognostic (3.13e-1)" "unprognostic (3.39e-2)" "unprognostic (1.95e-2)" "unprognostic (2.19e-1)" "prognostic favorable (1.96e-8)" "prognostic favorable (7.30e-4)" "unprognostic (5.85e-2)" "unprognostic (1.08e-2)" "unprognostic (2.91e-2)" "unprognostic (2.94e-2)" "unprognostic (2.19e-1)" "unprognostic (1.48e-1)" 2.8 4.7 5.1 2.8 4.7 2.4 5.2 7.4 6.1 4.2 6.4 3.2 2.6 3.3 6.1 2.1 4.9 2.8 2.1 4.5 3.3 5.4 5.6 3.3 4.9 4.2 3.1 6.8 5.1 5.4 3.5 3.6 4.4 4.3 4.1 5.4 3.6 2.9 2.2 6.8 3.1 2.2 2.1 5.9 4.4 4.5 4.4 5.7 7.8 2.2 3.5 2.2 2.6 7.3 0.3 0.6 3.7 5.2 2.7 2.4 4.0 2.0 1.5 2.7 3.6 0.4 2.7 3.5 5.6 1.3 2.4 1.3 2.1 0.9 4.9 0.9 2.7 0.8 0.9 1.3 1.5 3.6 1.4 2.5 1.2 1.7 0.6 2.5 0.2 4.9 5.5 0.9 4.4 2.4 8.5 3.4 4.1 0.1 1.3 4.1 2.1 1.8 3.2 4.2 6.5 2.9 0.3 0.2 1.6 7.1 4.9 3.2 0.6 0.4 0.9 3.5 1.7 0.7 3.0 4.4 0.2 0.4 1.4 8.9 1.3 6.7 3.5 1.7 3.8 5.5 4.8 4.7 1.2 4.9 6.7 6.2 6.9 7.1 2.2 1.9 3.2 1.9 5.1 4.7 7.4 6.1 4.5 3.3 4.2 3.1 4.4 2.1 4.4 7.3 6.1 28.9 13.6 14.7 13.6 2.8 6.5 3.8 8.6 15.9 8.6 8.0 6.0 18.6 10.8 7.3 6.2 9.1 5.1 3.8 21.5 8.7 39.2 9.6 8.7 7.7 6.7 10.1 17.5 4.9 6.9 9.5 9.2 7.8 3.8 19.0 7.1 8.5 3.4 3.3 20.8 5.1 8.2 3.1 4.0 7.6 11.5 5.4 5.4 12.2 4.5 11.4 23.7 20.6 20.4 4.4 6.1 6.0 3.7 5.0 10.9 13.6 12.2 8.1 19.7 6.0 7.5 14.0 17.3 9.4 2.0 6.8 10.3 37.2 5.8 4.6 ZNF519 "FLJ36809, HsT2362" ENSG00000175322 "Zinc finger protein 519" Q8TB69 18 14057457-14132490 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Excitatory neurons: 83.3;Inhibitory neurons: 64.3;Oligodendrocyte precursor cells: 30.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HL-60: 5.5;SCLC-21H: 6.6" HPA028982 Uncertain Approved Nucleoli NA NA "Cluster 72: Non-specific - Transcription" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoli "HPA028982: AB_10610705" "unprognostic (1.85e-2)" "unprognostic (4.22e-2)" "unprognostic (2.16e-1)" "unprognostic (1.15e-3)" "unprognostic (1.90e-1)" "unprognostic (2.53e-2)" "unprognostic (6.70e-2)" "unprognostic (3.43e-1)" "unprognostic (2.31e-2)" "unprognostic (1.18e-1)" "unprognostic (6.47e-2)" "unprognostic (1.50e-2)" "unprognostic (1.16e-5)" "unprognostic (1.40e-2)" "unprognostic (1.58e-1)" "unprognostic (2.38e-1)" "unprognostic (3.65e-4)" 0.9 0.5 0.3 0.3 0.3 0.3 0.9 1.3 1.0 2.4 0.0 2.4 0.1 1.9 0.3 1.7 1.5 0.4 0.8 0.3 0.2 0.3 0.4 0.5 0.6 0.2 0.2 2.0 0.6 0.2 0.8 0.2 0.3 1.2 0.5 0.4 0.8 0.4 0.4 0.9 1.0 0.7 0.2 0.9 0.7 0.8 0.2 0.6 0.9 0.3 0.4 1.6 1.7 0.4 0.6 0.0 2.3 2.2 0.0 0.5 0.9 0.4 0.3 1.7 1.6 0.7 0.6 1.2 0.8 0.2 0.5 0.6 2.3 0.3 2.5 1.0 1.4 2.7 1.3 0.4 0.0 5.5 0.8 0.1 0.6 1.2 0.3 0.3 0.2 1.9 0.9 1.8 0.7 0.3 3.7 0.8 0.9 1.2 0.7 3.3 2.9 1.6 0.3 0.4 6.6 1.2 1.2 0.1 0.8 1.8 0.4 0.8 0.2 2.7 2.5 1.1 0.9 0.3 0.6 1.3 0.7 1.8 1.8 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.2 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.3 1.3 1.0 0.3 0.2 0.2 0.2 0.3 0.2 0.2 0.4 4.6 6.4 9.5 17.6 7.6 2.0 2.4 2.5 11.4 15.0 2.8 3.8 4.9 1.5 1.3 0.0 2.1 3.2 3.3 0.6 1.9 2.5 1.1 0.6 11.2 3.2 1.2 8.0 83.3 2.0 4.2 7.6 3.1 1.1 3.8 18.2 2.9 0.7 1.7 3.3 64.3 1.9 4.1 3.1 1.9 1.8 6.5 2.3 1.8 23.4 1.6 5.9 6.2 30.2 15.9 1.0 0.4 9.1 6.0 1.2 0.3 0.7 2.0 7.4 0.0 8.4 4.2 10.7 12.2 18.3 1.3 0.8 6.4 3.6 2.4 1.4 ZNF532 FLJ10697 ENSG00000074657 "Zinc finger protein 532" Q9HCE3 18 58862600-58986480 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 90.1;Excitatory neurons: 86.9;Inhibitory neurons: 90.9;Oligodendrocyte precursor cells: 130.2;Oligodendrocytes: 178.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 3.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 118.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015322 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 37: B-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "Golgi apparatus" "HPA015322: AB_2304947" "unprognostic (3.43e-1)" "unprognostic (4.36e-2)" "unprognostic (1.41e-3)" "prognostic unfavorable (6.46e-5)" "unprognostic (4.24e-1)" "unprognostic (5.84e-2)" "unprognostic (1.50e-3)" "unprognostic (7.40e-2)" "unprognostic (5.33e-2)" "unprognostic (1.42e-1)" "unprognostic (2.09e-3)" "unprognostic (1.90e-1)" "unprognostic (7.60e-3)" "unprognostic (1.06e-2)" "unprognostic (1.85e-1)" "unprognostic (5.53e-2)" "prognostic unfavorable (5.76e-4)" 24.0 12.5 33.5 15.7 53.1 1.4 17.9 73.9 39.8 30.3 12.4 25.9 7.2 65.1 20.1 22.3 26.2 24.5 36.0 34.3 45.0 14.1 4.2 19.9 14.2 55.2 44.2 52.8 6.8 16.3 15.7 26.4 56.6 48.0 13.3 25.7 15.8 34.1 61.1 16.5 12.0 41.4 33.8 17.0 12.8 24.2 46.1 11.9 24.7 49.8 17.4 23.0 21.3 84.8 21.3 30.0 118.8 63.4 18.5 42.2 5.8 37.6 35.2 26.0 23.4 10.2 23.0 26.5 28.3 47.2 12.9 34.1 1.0 29.7 26.7 19.5 25.0 0.0 51.8 0.6 24.5 0.2 0.2 33.1 54.5 27.2 49.5 34.4 28.8 0.0 0.3 31.9 30.8 0.0 0.2 0.3 63.0 1.0 19.9 0.6 31.6 4.2 18.1 2.8 27.1 70.3 24.2 2.6 40.8 78.8 30.3 17.3 22.0 70.7 50.1 0.5 30.7 0.4 21.7 7.3 24.0 0.0 55.2 0.0 0.3 0.0 0.4 1.1 0.1 3.7 0.2 0.2 0.7 1.6 0.0 0.1 0.0 0.2 0.2 0.1 0.0 0.4 33.5 53.1 73.9 39.8 34.3 45.0 55.2 44.2 56.6 33.8 46.1 84.8 16.6 12.8 12.2 90.1 13.2 10.6 12.5 8.0 12.0 28.8 9.3 8.8 17.0 5.7 10.1 1.8 27.1 2.0 1.4 0.3 0.0 4.9 4.9 8.3 48.3 24.2 4.2 0.0 86.9 0.5 2.7 17.9 3.1 10.0 0.0 15.8 14.6 0.1 4.4 35.3 90.9 0.2 4.1 9.1 14.3 3.5 11.5 9.2 8.8 53.4 5.2 22.1 0.0 130.2 178.2 6.0 1.4 18.0 8.6 33.5 0.0 1.6 8.8 9.7 13.1 15.5 24.2 5.5 17.2 8.9 9.2 3.4 4.3 5.0 0.3 11.9 ZNF680 FLJ90430 ENSG00000173041 "Zinc finger protein 680" Q8NEM1 7 64519878-64563075 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 116.9;Oligodendrocytes: 89.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA003173 Approved Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA003173: AB_1080744" "unprognostic (1.65e-1)" "unprognostic (3.21e-2)" "unprognostic (6.88e-2)" "unprognostic (7.41e-2)" "unprognostic (1.52e-3)" "unprognostic (3.62e-2)" "unprognostic (1.79e-1)" "unprognostic (2.07e-1)" "unprognostic (1.07e-2)" "unprognostic (1.20e-1)" "unprognostic (2.46e-1)" "unprognostic (5.72e-2)" "unprognostic (1.35e-1)" "unprognostic (8.66e-2)" "unprognostic (2.21e-1)" "unprognostic (2.26e-1)" "unprognostic (8.05e-3)" 5.9 13.7 8.8 3.8 10.6 2.4 13.1 15.0 15.5 6.1 3.3 3.8 2.8 4.9 5.7 3.6 5.0 5.3 11.3 8.5 9.4 8.4 20.1 4.9 6.5 9.3 10.4 10.9 4.8 3.7 4.0 4.6 9.7 10.1 5.1 4.8 4.2 5.4 11.6 5.8 3.3 4.5 9.6 6.7 6.3 4.2 10.1 6.6 24.9 15.2 5.4 4.5 4.1 12.4 5.6 3.2 12.8 15.3 6.2 6.9 8.0 4.4 3.6 7.9 9.8 4.4 10.6 10.6 10.7 4.2 9.0 3.8 10.5 4.9 12.9 2.0 7.4 8.1 6.7 4.0 2.6 10.8 7.1 4.6 5.8 7.0 7.9 9.9 7.5 14.6 14.8 0.0 11.1 4.4 16.8 17.1 15.0 5.0 3.9 13.0 12.7 32.1 10.8 17.6 10.1 13.8 13.5 12.7 4.9 23.5 12.7 4.6 4.0 9.6 4.8 4.5 7.8 9.1 12.3 29.9 0.5 9.8 8.6 2.8 0.5 0.6 1.5 0.7 1.2 2.2 2.1 1.8 0.9 1.5 2.2 2.1 0.2 4.6 0.6 0.7 0.6 0.8 8.8 10.6 15.0 15.5 8.5 9.4 9.3 10.4 9.7 9.6 10.1 12.4 10.2 12.8 5.1 116.9 15.4 4.2 10.7 9.4 19.9 12.5 17.5 9.5 13.3 14.3 11.6 25.8 4.2 12.0 11.5 2.8 9.8 8.9 0.9 8.9 9.1 11.0 0.0 7.2 57.7 9.1 10.7 13.4 11.7 6.4 7.0 34.0 23.9 21.5 5.3 1.7 60.5 4.4 16.2 10.1 6.4 2.4 27.7 6.2 7.2 41.2 7.3 23.8 23.7 59.8 89.2 5.8 3.1 22.2 6.3 9.5 3.1 7.1 6.8 9.3 19.7 15.2 9.7 13.7 15.1 6.5 5.3 7.1 11.2 16.5 5.3 9.4 ZNF71 "Cos26, EZFIT" ENSG00000197951 "Zinc finger protein 71" Q9NQZ8 19 56595300-56626481 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 20.6" HPA018124 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoli Nucleoplasm "HPA018124: AB_1848339" "unprognostic (1.93e-2)" "unprognostic (7.95e-2)" "unprognostic (1.32e-1)" "unprognostic (1.96e-2)" "unprognostic (7.72e-2)" "unprognostic (5.03e-2)" "unprognostic (5.06e-3)" "unprognostic (1.27e-1)" "unprognostic (2.09e-1)" "unprognostic (1.39e-1)" "unprognostic (1.12e-3)" "unprognostic (1.90e-3)" "unprognostic (3.91e-2)" "unprognostic (4.34e-2)" "unprognostic (1.08e-1)" "unprognostic (2.05e-1)" "unprognostic (6.97e-3)" 3.3 2.1 3.1 2.0 2.9 1.1 3.1 2.4 4.8 3.3 0.0 3.9 1.3 4.3 1.3 2.5 3.1 1.9 3.9 4.9 2.0 2.4 0.9 2.4 3.0 1.9 2.5 3.6 2.5 2.4 2.9 2.1 1.7 3.1 1.1 3.3 2.5 2.7 3.5 2.8 2.2 2.5 1.0 2.7 2.5 3.2 2.0 3.2 2.3 2.7 1.5 3.5 2.7 2.3 3.1 7.9 9.1 8.7 3.1 3.3 5.7 3.2 3.9 3.6 4.0 1.5 1.4 3.3 3.2 3.5 3.3 1.1 2.0 3.5 2.1 0.0 20.6 5.4 0.9 3.0 3.7 6.4 4.3 4.7 3.4 3.1 2.6 4.0 4.6 7.2 2.3 0.0 3.4 0.0 12.5 2.3 9.0 0.0 7.9 4.8 6.9 3.0 2.1 5.8 9.0 10.5 2.9 4.5 4.4 3.7 3.4 6.3 5.3 10.5 5.1 2.6 6.4 2.2 3.0 5.0 3.0 3.8 3.1 2.9 1.7 3.5 4.3 1.4 4.5 3.2 3.3 3.6 2.8 3.5 3.4 3.6 0.6 6.1 2.6 2.3 3.7 2.6 3.1 2.9 2.4 4.8 4.9 2.0 1.9 2.5 1.7 1.0 2.0 2.3 8.9 3.2 1.7 3.9 4.5 2.9 2.8 3.8 2.8 9.3 4.8 4.3 3.9 4.3 2.0 7.3 4.2 4.9 5.5 0.6 3.9 10.1 2.7 2.5 3.5 9.8 2.4 2.5 7.4 4.9 6.8 4.6 1.5 2.1 0.0 7.8 3.6 1.0 5.7 11.8 6.6 2.1 4.1 2.4 5.2 3.6 6.2 3.5 3.6 1.9 4.2 3.4 12.3 5.0 4.8 6.3 1.9 5.7 1.4 2.4 1.0 5.8 0.9 8.1 0.0 5.1 6.3 7.4 10.7 2.3 4.3 1.5 5.5 5.5 2.3 1.4 ZNF738 ENSG00000172687 "Zinc finger protein 738" Q8NE65 19 21358930-21379302 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 38.6;Sertoli cells: 32.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 49.5;NTERA-2: 51.6" HPA059135 Uncertain NA NA "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "HPA059135: AB_2683918" "unprognostic (1.00e-1)" "unprognostic (1.59e-1)" "unprognostic (4.48e-2)" "unprognostic (4.35e-3)" "unprognostic (4.47e-2)" "unprognostic (1.37e-1)" "unprognostic (1.55e-2)" "unprognostic (6.22e-2)" "unprognostic (4.27e-3)" "prognostic favorable (2.27e-4)" "unprognostic (2.10e-1)" "unprognostic (3.51e-2)" "unprognostic (7.39e-5)" "unprognostic (2.34e-2)" "unprognostic (2.40e-1)" "unprognostic (1.29e-1)" "unprognostic (4.20e-2)" 3.4 2.7 4.7 3.6 6.8 13.3 3.7 7.0 7.0 4.8 3.5 3.0 3.2 5.8 4.1 3.7 3.9 2.9 2.7 4.6 5.3 3.6 0.7 3.3 6.9 6.5 6.2 9.3 2.8 2.3 2.6 7.0 6.2 3.8 4.1 5.5 3.7 3.1 1.6 3.5 3.5 4.1 5.3 4.1 3.3 5.0 6.2 6.9 3.9 1.4 6.6 3.5 4.0 9.0 3.2 1.7 49.5 18.7 5.9 4.7 33.2 11.8 4.8 23.1 23.7 3.8 14.7 10.6 12.1 4.5 13.8 8.5 17.8 5.8 31.4 14.0 13.2 7.9 3.6 3.1 3.3 0.2 2.8 4.2 3.4 13.2 7.1 8.0 10.2 29.0 0.1 0.4 14.2 3.3 41.4 14.4 51.6 0.0 8.5 42.4 19.3 6.4 5.9 7.6 22.0 10.9 4.1 0.2 6.4 34.7 5.3 30.5 6.4 2.6 2.8 14.3 10.7 1.1 17.7 28.4 0.2 0.2 5.0 5.6 3.4 4.7 2.0 3.8 1.8 4.0 2.5 2.5 3.0 4.4 2.4 2.4 5.2 4.5 4.8 3.0 4.3 1.7 4.7 6.8 7.0 7.0 4.6 5.3 6.5 6.2 6.2 5.3 6.2 9.0 5.3 9.6 1.1 5.2 8.9 3.4 6.2 7.8 4.0 10.4 7.1 6.7 1.6 4.3 4.6 14.7 14.6 24.2 8.7 1.4 7.9 6.1 2.3 5.3 7.6 7.9 4.2 10.1 5.7 7.6 24.3 8.4 4.6 5.2 2.5 38.6 5.7 0.1 11.1 0.0 8.8 2.5 6.1 10.6 5.1 2.2 5.3 8.1 5.4 5.6 2.0 4.2 6.2 13.6 23.7 6.5 0.6 4.1 6.3 3.8 1.4 1.5 3.5 15.1 32.9 3.7 8.5 17.2 20.0 7.7 1.8 15.6 5.5 19.7 4.8 5.7 ZNF761 "FLJ16231, FLJ35333, KIAA2033" ENSG00000160336 "Zinc finger protein 761" Q86XN6 19 53431984-53461862 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "prostate: 73.9" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 45.3" "Cancer enriched" "Detected in all" 5 "prostate cancer: 31.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (8.10e-2)" "unprognostic (1.64e-1)" "unprognostic (2.89e-2)" "unprognostic (1.39e-1)" "unprognostic (7.03e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (4.68e-2)" "unprognostic (3.74e-3)" "unprognostic (1.12e-1)" "unprognostic (2.19e-3)" "unprognostic (1.59e-1)" "unprognostic (2.33e-3)" "unprognostic (1.19e-1)" "unprognostic (4.13e-1)" "unprognostic (8.71e-2)" "unprognostic (1.38e-3)" 8.3 9.8 8.7 6.4 10.0 10.6 10.6 15.8 10.5 7.3 9.4 7.1 6.6 6.2 11.0 5.7 9.1 6.5 5.3 9.6 10.3 7.9 6.1 7.1 8.7 9.5 9.0 12.2 11.8 11.9 7.3 17.0 10.2 73.9 8.7 7.2 8.7 6.2 4.7 11.1 6.8 6.6 7.4 8.1 9.2 6.1 9.9 8.2 8.2 4.7 8.4 8.3 7.7 12.7 17.3 9.6 6.9 14.4 21.0 17.2 25.1 11.0 9.9 7.9 12.0 11.9 6.9 16.2 6.1 10.7 11.4 11.8 18.2 11.9 12.5 2.2 25.9 15.5 12.7 15.4 12.9 1.5 18.4 17.1 13.5 9.5 16.8 11.1 8.9 15.7 16.4 10.7 14.5 10.6 19.0 15.3 12.0 17.1 14.5 15.2 15.2 17.2 8.7 48.9 8.9 6.8 13.2 18.6 8.0 22.4 10.1 14.4 7.6 12.3 9.5 1.7 13.0 13.0 27.6 26.6 0.5 8.8 10.8 7.2 4.4 5.8 5.1 4.8 6.3 6.6 5.9 6.4 4.8 6.4 6.4 6.8 3.8 12.8 4.7 5.2 8.4 4.5 8.7 10.0 15.8 10.5 9.6 10.3 9.5 9.0 10.2 7.4 9.9 12.7 6.7 3.2 7.3 3.6 6.4 0.0 12.0 0.0 2.8 1.1 7.5 6.1 6.6 12.8 4.3 3.7 0.0 17.3 4.9 4.9 23.5 4.3 0.5 6.2 4.9 5.3 2.4 7.8 2.5 2.9 14.3 7.5 6.1 6.3 9.5 12.0 9.7 10.0 8.6 5.0 5.0 11.5 0.0 7.1 0.0 1.3 12.5 5.0 0.0 3.7 3.5 1.8 5.2 1.5 7.0 5.4 6.1 7.9 9.2 19.6 5.2 11.5 2.2 0.9 19.7 3.7 5.0 1.5 5.6 5.7 0.0 45.3 4.7 5.1 6.7 12.1 ZNF770 "FLJ20582, PRO1914" ENSG00000198146 "Zinc finger protein 770" Q6IQ21 15 34978341-34988287 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024518 Approved NA NA "Cluster 32: T-cells - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 30: Epithelial cell lines - Translation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA024518: AB_1859449" "unprognostic (1.04e-1)" "unprognostic (1.60e-2)" "unprognostic (1.75e-2)" "unprognostic (2.79e-1)" "unprognostic (2.32e-2)" "unprognostic (1.17e-1)" "unprognostic (3.11e-1)" "unprognostic (6.67e-2)" "unprognostic (1.05e-1)" "unprognostic (1.28e-1)" "unprognostic (2.67e-3)" "unprognostic (4.24e-2)" "unprognostic (2.09e-3)" "unprognostic (1.20e-1)" "unprognostic (1.41e-1)" "unprognostic (5.06e-2)" "unprognostic (2.10e-3)" 12.7 12.9 12.2 12.7 16.7 8.9 18.6 16.9 16.3 13.2 12.2 9.7 12.2 15.1 44.9 28.9 17.7 9.0 14.8 14.1 11.4 21.6 29.4 9.8 17.6 9.5 12.3 17.8 10.7 22.2 5.4 22.5 10.0 13.2 9.9 19.7 15.0 12.0 18.6 35.3 11.6 10.7 11.3 15.4 11.7 13.6 12.4 16.6 44.2 19.8 21.9 12.2 12.8 11.5 18.9 23.1 31.8 40.5 25.1 23.9 17.9 22.0 21.0 21.1 23.1 20.5 12.7 18.0 29.6 21.8 20.8 44.7 37.9 30.1 29.5 23.1 16.1 41.9 33.2 23.5 50.7 44.1 26.7 16.3 74.1 19.0 52.8 28.0 24.7 13.4 48.0 26.5 29.0 11.1 30.6 21.9 26.2 29.2 23.6 35.1 29.9 24.8 28.2 34.4 45.3 26.1 32.9 37.3 19.9 25.4 26.8 26.3 21.6 37.1 15.6 21.1 21.3 16.6 28.2 28.7 30.6 32.2 27.5 2.1 3.8 1.3 3.9 3.2 5.5 4.9 4.1 3.4 3.2 4.9 6.0 4.9 4.5 4.2 3.6 3.3 4.8 2.6 12.2 16.7 16.9 16.3 14.1 11.4 9.5 12.3 10.0 11.3 12.4 11.5 20.5 16.0 29.3 26.8 40.3 64.6 40.1 25.4 39.9 25.6 27.5 25.8 13.4 20.0 28.8 33.1 22.9 17.5 32.8 9.8 31.3 21.1 15.8 29.2 30.5 24.9 27.1 13.5 21.6 24.0 14.2 24.2 20.9 26.3 22.1 26.6 27.5 68.1 13.9 25.2 24.8 24.4 14.2 22.9 18.8 8.7 25.4 18.6 39.2 12.2 38.9 29.4 32.0 22.1 19.8 25.3 11.1 23.0 19.8 42.1 12.1 54.3 19.8 21.1 0.0 32.3 18.3 63.8 52.5 64.1 91.1 19.8 26.4 33.3 23.5 39.8 ZNF813 FLJ16542 ENSG00000198346 "Zinc finger protein 813" Q6ZN06 19 53467733-53496255 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 13.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RT4: 18.1" HPA056406 Uncertain Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 68: Epididymis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA056406: AB_2683119" "unprognostic (1.20e-1)" "unprognostic (3.43e-2)" "unprognostic (1.17e-1)" "unprognostic (3.98e-3)" "unprognostic (2.28e-1)" "unprognostic (3.61e-3)" "unprognostic (1.48e-2)" "unprognostic (1.84e-3)" "unprognostic (3.39e-3)" "unprognostic (1.74e-1)" "unprognostic (3.75e-2)" "unprognostic (3.61e-2)" "unprognostic (1.25e-3)" "unprognostic (8.18e-2)" "unprognostic (1.97e-1)" "unprognostic (1.77e-2)" "unprognostic (6.56e-2)" 1.2 1.1 0.9 1.5 1.3 1.4 2.2 1.1 1.1 1.1 1.4 1.8 1.8 1.3 3.9 1.2 1.8 1.4 0.7 1.0 1.2 1.3 0.7 1.4 2.2 1.4 1.4 1.8 1.3 2.4 0.6 3.6 1.3 4.9 1.7 0.6 1.2 1.1 0.4 2.0 1.7 1.0 1.0 1.9 1.9 1.6 1.3 2.2 1.9 0.5 2.1 1.4 1.2 1.8 0.9 0.8 2.6 4.3 2.2 2.6 6.0 2.4 2.4 1.6 2.3 4.6 2.7 6.9 2.3 2.3 3.0 1.4 6.3 2.7 3.0 0.0 9.9 6.9 1.8 5.2 1.1 0.0 7.1 2.2 2.2 1.8 1.3 0.9 1.4 4.9 3.8 0.1 2.6 1.3 9.2 3.8 3.3 0.8 2.4 5.6 5.7 3.4 1.5 18.1 1.1 2.5 0.0 4.5 1.6 5.6 1.8 3.4 2.3 0.9 3.1 0.1 2.3 3.6 5.5 7.5 0.0 0.0 4.7 1.8 1.1 0.8 1.7 1.6 1.7 1.6 1.6 1.9 1.2 2.4 3.0 2.3 0.5 3.6 3.0 1.1 1.3 1.4 0.9 1.3 1.1 1.1 1.0 1.2 1.4 1.4 1.3 1.0 1.3 1.8 3.4 6.4 1.8 0.3 4.4 1.8 3.1 1.4 4.6 0.7 1.9 1.8 1.9 5.7 2.6 0.0 0.0 5.0 4.3 2.5 1.9 2.2 1.7 2.6 3.2 4.0 0.0 3.4 0.3 1.2 10.1 4.1 3.6 2.6 0.0 7.0 13.6 1.2 2.8 3.3 1.0 3.2 2.0 3.0 1.7 0.9 2.5 2.6 3.6 1.0 3.7 1.1 3.1 2.0 2.8 1.5 3.4 2.2 1.5 5.0 1.2 0.8 2.0 0.6 0.0 4.0 3.4 0.9 4.1 2.2 1.6 8.9 2.8 2.6 3.9 2.3 ZNF831 "C20orf174, dJ492J12.1" ENSG00000124203 "Zinc finger protein 831" Q5JPB2 20 59123381-59259113 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.4;lymphoid tissue: 6.2" "Group enriched" "Detected in some" 4 "dendritic cells: 20.5;Excitatory neurons: 19.5;NK-cells: 17.5;Plasma cells: 9.5;T-cells: 31.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "NK-cells: 1.2;T-cells: 2.1" "Group enriched" "Detected in some" 6 "Daudi: 4.0;HMC-1: 1.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 25 "amygdala: 4.6;basal ganglia: 4.1;cerebral cortex: 3.4;hippocampal formation: 5.0;olfactory bulb: 5.4" HPA016839 Uncertain NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA016839: AB_1859466" "unprognostic (2.90e-3)" "unprognostic (7.70e-6)" "unprognostic (9.71e-4)" "unprognostic (1.31e-3)" "unprognostic (7.00e-2)" "unprognostic (3.00e-5)" "unprognostic (3.08e-3)" "unprognostic (2.23e-2)" "unprognostic (2.89e-3)" "unprognostic (2.21e-3)" "unprognostic (2.80e-3)" "unprognostic (4.31e-1)" "unprognostic (3.40e-3)" "unprognostic (2.39e-1)" "unprognostic (3.42e-2)" "unprognostic (2.21e-1)" "unprognostic (1.93e-2)" 0.3 0.1 2.2 2.3 1.6 0.9 0.3 0.0 2.7 0.1 0.0 0.3 0.2 0.1 0.2 0.2 0.2 0.5 0.0 3.4 0.3 0.1 0.2 0.6 6.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.1 1.9 0.0 0.0 2.6 0.6 0.2 0.9 1.5 0.3 0.0 3.8 0.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.8 0.0 1.4 0.2 1.0 1.5 0.0 0.1 0.8 1.0 0.1 1.2 0.0 0.0 2.1 0.4 2.2 1.6 0.0 2.7 3.4 0.3 0.0 0.0 0.0 0.0 0.9 0.2 0.3 0.0 0.6 0.7 4.8 0.3 0.0 0.0 0.0 0.0 0.2 0.4 0.7 0.0 0.0 1.8 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 19.5 0.0 0.0 0.1 0.5 0.1 2.5 0.0 0.7 0.0 0.0 0.0 2.0 0.0 0.0 0.6 0.0 0.1 0.0 1.0 0.0 0.0 0.1 0.0 17.5 0.5 0.9 0.0 0.0 0.0 9.5 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.3 0.5 0.5 0.0 0.0 0.0 31.2 0.0 0.0 0.0 ZNRF2 RNF202 ENSG00000180233 "Zinc and ring finger 2" Q8NHG8 7 30284597-30367689 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 119.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072244 Approved Uncertain "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" "Nucleoli fibrillar center" "HPA072244: AB_2732197" "unprognostic (9.44e-2)" "unprognostic (2.38e-2)" "unprognostic (8.64e-2)" "prognostic unfavorable (7.68e-4)" "unprognostic (4.46e-2)" "unprognostic (1.24e-1)" "unprognostic (3.06e-1)" "unprognostic (6.10e-2)" "unprognostic (1.26e-1)" "unprognostic (1.67e-1)" "unprognostic (1.71e-1)" "unprognostic (5.93e-2)" "prognostic favorable (2.29e-4)" "unprognostic (1.51e-1)" "unprognostic (2.71e-1)" "prognostic favorable (8.71e-4)" "unprognostic (8.67e-2)" 7.4 6.5 4.8 11.5 5.3 13.0 9.6 5.5 4.2 5.1 14.5 18.9 13.2 8.4 10.7 10.4 4.4 9.4 5.1 4.3 4.0 22.0 21.5 7.4 15.3 7.4 6.6 3.7 10.3 9.1 5.0 9.3 6.0 5.7 16.2 4.7 9.2 5.3 5.7 10.0 15.2 9.5 7.5 10.8 15.0 24.0 7.9 8.9 11.7 6.2 13.2 11.2 4.2 8.4 13.2 4.7 3.8 3.4 4.4 3.0 19.8 4.9 5.1 5.4 7.2 2.4 21.5 13.8 12.6 4.1 14.0 12.5 12.7 8.5 5.7 13.4 11.5 8.6 9.7 6.4 2.3 6.7 15.6 4.6 14.0 3.7 9.1 5.6 4.6 10.5 10.7 26.6 5.9 5.1 13.6 17.5 8.9 13.2 5.9 11.7 8.2 23.8 16.4 28.0 13.0 12.3 9.9 41.2 8.5 22.2 11.1 26.5 5.1 5.2 8.9 5.0 10.5 44.9 41.5 18.1 5.7 14.3 7.8 0.2 0.3 0.4 0.3 0.3 0.5 0.4 0.4 0.5 0.3 0.2 0.2 0.4 0.5 0.3 0.4 2.2 1.0 0.2 4.8 5.3 5.5 4.2 4.3 4.0 7.4 6.6 6.0 7.5 7.9 8.4 11.3 9.6 8.4 19.9 13.9 15.9 7.4 4.8 8.6 11.3 26.5 10.4 3.6 14.3 5.0 16.5 41.7 10.1 40.8 60.0 7.9 4.9 5.2 32.7 7.6 6.6 31.3 6.1 54.4 10.3 11.4 5.1 14.3 43.7 3.8 4.7 8.2 41.6 10.7 1.7 32.3 14.0 0.0 23.3 16.2 10.1 2.8 23.1 12.4 119.9 13.1 5.1 4.1 41.7 39.7 7.4 19.5 2.2 11.5 8.5 22.6 32.3 5.8 5.8 6.6 7.7 9.8 18.3 7.0 7.9 18.9 11.5 17.6 7.6 23.4 14.3