Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABHD12 "ABHD12A, BEM46L2, C20orf22, dJ965G21.2, DKFZP434P106" ENSG00000100997 "Abhydrolase domain containing 12, lysophospholipase" Q8N2K0 20 25294742-25390835 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Cataract, Deafness, Disease variant, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 315.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026866 Uncertain NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA026866: AB_1844446" "prognostic unfavorable (3.81e-5)" "prognostic favorable (1.30e-5)" "unprognostic (1.32e-1)" "unprognostic (8.74e-2)" "unprognostic (3.67e-2)" "unprognostic (6.56e-2)" "prognostic unfavorable (7.18e-4)" "unprognostic (8.51e-2)" "unprognostic (7.91e-3)" "unprognostic (2.08e-1)" "unprognostic (4.08e-2)" "unprognostic (8.46e-2)" "unprognostic (1.36e-3)" "unprognostic (2.45e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-1)" "unprognostic (8.11e-3)" 29.5 33.0 55.7 27.4 67.3 26.5 26.9 70.0 64.7 32.1 35.9 37.0 47.0 25.3 133.1 50.0 24.8 33.4 30.5 77.3 58.2 45.5 29.8 32.6 30.8 70.9 64.6 30.6 117.8 55.3 42.1 29.6 73.3 35.5 36.4 30.8 36.9 39.9 13.3 52.4 52.8 23.6 66.0 22.0 55.0 19.2 71.8 23.4 80.8 14.8 41.5 37.2 35.1 96.9 67.2 148.3 41.6 50.9 79.6 47.1 93.3 97.0 84.5 73.7 84.6 90.1 93.0 21.8 53.3 77.0 155.1 116.5 44.4 56.8 62.8 22.7 41.9 33.3 46.8 128.4 59.3 33.3 71.6 58.7 42.0 85.4 44.1 95.7 33.2 37.8 25.8 315.3 72.8 142.5 51.8 31.0 29.4 77.8 96.8 39.2 95.3 195.0 43.4 145.7 46.6 39.7 75.4 198.9 133.8 72.3 67.4 47.6 44.6 98.3 63.0 57.1 54.0 38.8 36.1 33.4 61.8 38.7 57.3 15.8 18.8 17.3 9.9 17.0 7.5 3.8 10.2 13.7 17.9 5.1 8.9 8.9 3.6 15.4 17.7 17.0 10.4 8.6 55.7 67.3 70.0 64.7 77.3 58.2 70.9 64.6 73.3 66.0 71.8 96.9 20.7 6.4 6.5 19.2 13.8 17.7 32.0 9.8 19.4 34.5 19.6 19.7 16.6 30.0 13.7 27.6 10.4 91.6 22.2 97.0 27.4 33.7 53.0 24.9 18.1 17.5 34.0 14.5 37.7 34.3 95.2 22.9 35.2 28.3 10.2 26.9 15.0 19.5 114.1 42.1 46.0 28.9 20.3 37.8 43.8 107.1 16.1 62.4 33.8 42.2 58.7 44.1 23.7 50.8 67.5 22.9 77.7 20.7 39.3 31.6 126.7 24.6 13.1 23.3 26.3 13.8 19.5 19.9 37.7 27.2 18.3 130.8 18.0 19.6 33.3 35.2 ACOT4 "FLJ31235, PTE-Ib, PTE2B" ENSG00000177465 "Acyl-CoA thioesterase 4" Q8N9L9 14 73591873-73595766 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 15.0;liver: 16.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 26.4;Proximal tubular cells: 59.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 17.6;MCF7: 14.1;SK-BR-3: 27.9;T-47d: 69.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA000779 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA000779: AB_1078093" "unprognostic (2.29e-3)" "unprognostic (2.53e-3)" "unprognostic (2.30e-1)" "unprognostic (2.29e-3)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "unprognostic (2.25e-2)" "unprognostic (3.10e-2)" "unprognostic (1.72e-2)" "unprognostic (9.56e-2)" "prognostic unfavorable (1.77e-4)" "unprognostic (3.95e-1)" "prognostic favorable (8.43e-5)" "unprognostic (2.47e-1)" "unprognostic (1.92e-1)" "unprognostic (7.31e-2)" "unprognostic (1.73e-1)" 4.9 1.4 3.7 1.1 3.7 0.6 4.6 4.2 4.3 3.9 2.4 3.0 4.3 0.8 2.6 1.5 0.9 0.9 0.9 3.6 2.9 15.0 16.8 3.6 1.3 3.1 2.7 0.9 1.5 1.0 0.4 1.8 3.3 1.4 3.4 0.8 1.7 1.8 0.6 0.6 3.3 1.5 2.5 1.5 2.0 2.2 2.9 1.0 1.3 0.6 1.3 1.2 0.9 3.2 10.7 2.9 0.3 0.1 1.3 0.6 0.0 0.6 0.0 0.7 1.2 0.3 17.6 0.0 0.6 1.0 0.0 1.1 0.0 0.1 0.1 5.8 0.1 0.0 3.5 0.0 2.0 0.0 9.5 0.8 1.3 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.6 14.1 0.3 1.9 0.9 3.7 2.8 0.0 0.0 0.0 0.4 5.2 1.5 0.3 6.9 27.9 2.1 0.1 69.7 10.5 0.2 0.0 6.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 11.5 0.0 1.4 14.7 0.6 7.3 2.1 6.9 8.4 0.4 3.3 4.0 8.5 0.0 7.2 0.2 0.9 7.2 5.3 3.7 3.7 4.2 4.3 3.6 2.9 3.1 2.7 3.3 2.5 2.9 3.2 0.4 0.0 2.7 1.0 1.0 0.3 1.1 3.8 1.2 0.2 5.5 4.2 1.7 7.2 2.8 11.0 0.0 15.9 3.6 8.3 15.6 4.2 1.8 4.1 1.1 0.5 0.0 0.0 1.4 9.2 13.8 1.5 3.1 5.6 5.7 4.1 0.0 26.4 11.2 1.7 0.8 3.2 8.2 3.0 0.3 5.3 0.3 2.1 0.0 1.9 1.0 0.7 11.3 0.5 0.3 6.2 2.6 0.4 1.5 1.1 15.7 59.8 2.9 0.5 0.0 1.5 1.1 3.2 15.8 2.6 0.3 4.5 5.1 0.4 2.6 1.3 APOC1 ENSG00000130208 "Apolipoprotein C1" P02654 19 44914247-44919349 "Cancer-related genes, Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "liver: 16232.1" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 33405.9" "Cancer enriched" "Detected in all" 21 "liver cancer: 3253.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "myeloid DC: 5.6" "Lineage enriched" "Detected in single" 12 "dendritic cells: 5.6" "Cell line enhanced" "Detected in many" "Hep G2: 576.4;HSkMC: 332.9;K-562: 151.6;SK-MEL-30: 268.0" "Low region specificity" "Detected in all" HPA051518 Supported "Secreted to blood" NA NA 20300000000 15000000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA051518: AB_2681519" "unprognostic (3.51e-2)" "unprognostic (3.31e-3)" "unprognostic (1.14e-1)" "unprognostic (2.59e-2)" "unprognostic (2.06e-1)" "unprognostic (1.47e-1)" "prognostic favorable (1.15e-7)" "unprognostic (9.51e-3)" "unprognostic (1.30e-1)" "unprognostic (4.18e-2)" "unprognostic (1.11e-1)" "unprognostic (2.52e-1)" "unprognostic (7.13e-3)" "unprognostic (3.48e-3)" "unprognostic (1.65e-1)" "unprognostic (2.01e-3)" "unprognostic (1.65e-1)" 59.2 1998.1 90.3 28.1 133.0 52.2 87.1 83.3 338.1 29.0 73.6 29.1 13.1 11.0 42.0 5.9 21.2 31.0 10.9 75.3 109.8 14.6 16232.1 289.9 140.1 133.2 152.8 56.4 21.4 16.3 23.6 41.7 121.9 14.4 16.7 15.1 35.5 2.2 22.2 73.1 49.1 4.0 92.7 254.9 22.7 18.7 139.2 37.4 36.3 6.1 33.9 23.5 11.3 169.4 2.7 26.5 12.0 5.0 37.1 38.2 111.5 1.3 1.7 4.8 7.3 55.6 49.9 8.4 9.4 1.0 3.2 1.8 15.6 1.9 2.3 0.4 63.5 36.8 4.2 576.4 32.9 27.5 18.1 332.9 2.8 4.8 1.8 9.2 1.3 1.8 151.6 0.8 1.7 3.6 1.5 2.0 112.4 10.4 5.6 6.2 16.0 0.8 7.3 2.0 5.3 3.3 18.9 0.3 268.0 37.7 2.2 98.4 4.2 0.4 1.7 0.2 1.7 4.5 5.4 8.2 0.7 7.4 2.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 5.6 0.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.3 90.3 133.0 83.3 338.1 75.3 109.8 133.2 152.8 121.9 92.7 139.2 169.4 22.9 115.4 214.4 2.3 40.6 17.0 4.1 5.8 6.2 2.5 49.8 92.8 0.8 453.2 55.8 1.8 0.0 31.7 1.6 2.4 49.0 4.6 1.2 6.6 128.4 68.9 2.4 768.8 0.3 4.0 341.3 93.0 19.4 5.0 142.6 30.6 432.6 33405.9 4789.8 0.0 0.5 3.2 4.1 867.7 27.3 22.8 270.9 620.5 30.2 3.7 124.5 276.0 0.0 0.0 0.0 3.2 0.3 259.5 1.3 4.2 0.6 16.6 24.4 9.9 19.7 1628.8 24.4 2.0 3.2 3.7 17.8 71.6 46.7 1226.7 2.1 5.0 APOE AD2 ENSG00000130203 "Apolipoprotein E" P02649 19 44905791-44909393 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Hyperlipidemia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adrenal gland: 3453.9;liver: 6592.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 9363.4;Hofbauer cells: 6072.6;Muller glia cells: 9454.8;Peritubular cells: 4958.2;Proximal tubular cells: 8155.9;Theca cells: 7201.0" "Cancer enhanced" "Detected in all" "liver cancer: 3183.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1867.0;CACO-2: 466.1;Hep G2: 935.3;HSkMC: 1374.2;SK-MEL-30: 1956.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008363, HPA065539, HPA068768, CAB069921" Enhanced Approved Vesicles "Secreted to blood" NA NA 51800000000 29000000000 "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB008363: AB_590560, CAB069921: AB_920623, HPA065539: AB_2685509, HPA068768: AB_2686029" "unprognostic (8.98e-2)" "unprognostic (2.32e-2)" "unprognostic (2.49e-2)" "unprognostic (5.28e-2)" "unprognostic (3.77e-2)" "unprognostic (7.25e-2)" "unprognostic (5.22e-3)" "unprognostic (6.13e-2)" "unprognostic (5.06e-2)" "unprognostic (4.13e-1)" "unprognostic (5.78e-2)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (7.76e-2)" "unprognostic (1.64e-1)" "unprognostic (1.12e-3)" "unprognostic (4.13e-2)" 522.1 3453.9 813.4 92.8 1164.2 66.5 325.1 775.0 943.2 271.2 329.2 130.9 40.3 81.5 20.0 37.2 72.2 100.2 176.3 606.1 841.6 1066.0 6592.5 258.8 352.2 1016.0 1037.0 508.2 41.9 34.5 110.9 102.2 1106.9 45.4 22.9 87.6 80.5 10.8 31.1 381.2 165.9 12.6 823.2 620.3 83.3 140.5 962.6 57.8 146.4 10.4 46.1 93.4 135.5 964.4 3.2 5.2 9.5 2.6 1867.0 76.3 69.4 1.5 4.3 8.4 1.4 466.1 2.8 2.0 9.9 0.3 9.1 6.4 12.6 2.1 0.7 1.7 4.0 3.3 1.7 935.3 192.4 6.8 2.3 1374.2 2.5 14.8 1.3 15.6 1.0 0.7 124.9 2.8 1.2 3.3 1.9 2.5 243.2 3.0 1.3 2.6 8.0 1.8 2.8 0.9 5.6 2.4 4.5 1.4 1956.0 131.6 165.3 52.8 3.3 13.2 3.1 1.4 1.6 5.9 8.6 3.8 5.9 4.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 813.4 1164.2 775.0 943.2 606.1 841.6 1016.0 1037.0 1106.9 823.2 962.6 964.4 136.7 0.0 8.2 444.0 66.1 935.2 12.3 18.3 67.7 81.7 86.7 565.8 2.2 450.4 5.2 228.1 41.7 46.3 6.0 2.2 682.9 1.8 73.6 33.8 936.6 140.2 0.0 331.6 1.1 0.7 43.8 860.7 3.6 22.9 174.4 103.6 208.9 9363.4 6072.6 38.7 2.1 0.6 4.1 718.0 292.6 355.3 2629.4 940.6 2481.3 60.9 70.3 9454.8 0.0 12.1 2.2 0.6 0.3 4958.2 7.2 15.0 0.2 8155.9 1.0 311.4 223.5 2958.4 345.5 14.8 12.8 15.1 1684.9 74.3 60.6 7201.0 1.7 4.7 C1QA ENSG00000173372 "Complement C1q A chain" P02745 1 22636628-22639678 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 1092.6" "Group enriched" "Detected in many" 9 "Hofbauer cells: 1663.2;Kupffer cells: 5007.4;Macrophages: 1874.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39 "intermediate monocyte: 226.1;non-classical monocyte: 181.7" "Lineage enriched" "Detected in many" 60 "monocytes: 226.1" "Cell line enhanced" "Detected in some" "HMC-1: 2.3;NB-4: 1.4;RPMI-8226: 7.1;SCLC-21H: 3.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002350, CAB009823" Supported "Secreted to blood" NA NA 2700000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009823: AB_2228238, HPA002350: AB_1078552" "unprognostic (1.97e-1)" "unprognostic (1.14e-2)" "unprognostic (1.98e-3)" "unprognostic (3.07e-2)" "unprognostic (6.10e-2)" "unprognostic (2.60e-1)" "unprognostic (1.16e-1)" "unprognostic (2.13e-1)" "unprognostic (1.67e-2)" "unprognostic (1.99e-1)" "unprognostic (4.42e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (1.58e-6)" "unprognostic (1.54e-1)" "unprognostic (2.11e-3)" "unprognostic (2.75e-2)" "unprognostic (7.30e-2)" 375.1 235.6 86.6 134.0 85.6 53.9 95.9 85.8 135.3 75.8 120.0 142.8 172.3 43.1 26.0 58.3 75.6 172.4 74.8 82.9 93.7 56.2 208.8 404.3 532.3 126.7 110.1 37.5 34.3 26.2 46.3 256.3 110.3 47.1 120.2 4.1 48.1 54.6 14.8 21.8 190.1 195.0 107.5 1092.6 90.8 38.2 109.4 100.3 36.5 49.3 68.0 257.5 30.4 131.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.4 0.3 0.0 0.0 0.5 0.2 7.1 0.0 0.0 3.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.4 0.1 0.8 0.0 0.0 0.1 0.1 0.0 0.1 5.2 0.1 0.1 226.1 0.0 0.0 0.1 0.1 3.7 0.0 0.0 0.0 0.5 0.3 181.7 0.0 0.0 9.7 86.6 85.6 85.8 135.3 82.9 93.7 126.7 110.1 110.3 107.5 109.4 131.6 17.4 35.3 55.8 0.0 19.0 18.4 2.3 0.0 2.2 0.4 5.1 24.6 8.9 37.1 18.0 0.0 0.0 8.7 2.7 0.5 0.0 0.0 4.5 0.2 0.5 46.0 1.8 41.0 0.0 0.2 11.3 9.6 0.0 0.2 21.5 0.2 76.1 26.2 1663.2 0.0 0.0 0.1 0.0 5007.4 291.4 9.9 13.1 1874.2 26.6 20.6 16.7 0.3 0.0 0.0 0.1 0.0 0.1 0.4 2.8 1.3 0.1 1.1 15.3 0.8 78.9 7.4 4.6 0.7 2.1 4.2 16.8 18.2 11.8 0.0 0.2 1.3 C1QB ENSG00000173369 "Complement C1q B chain" 1 22652762-22661637 "Human disease related genes, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "lung: 546.4;lymphoid tissue: 990.2" "Group enriched" "Detected in many" 28 "Hofbauer cells: 1451.0;Kupffer cells: 4559.7;Macrophages: 1747.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 71 "intermediate monocyte: 140.6;non-classical monocyte: 101.2" "Lineage enriched" "Detected in many" 85 "monocytes: 140.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052116 Approved "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA052116: AB_2681735" "unprognostic (1.42e-1)" "unprognostic (3.36e-2)" "unprognostic (5.61e-3)" "unprognostic (8.20e-2)" "unprognostic (5.93e-2)" "unprognostic (4.09e-1)" "unprognostic (1.25e-1)" "unprognostic (2.35e-1)" "unprognostic (2.87e-2)" "unprognostic (2.21e-1)" "unprognostic (2.63e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (9.58e-6)" "unprognostic (4.14e-2)" "unprognostic (7.76e-3)" "unprognostic (4.83e-2)" "unprognostic (2.35e-2)" 439.2 229.0 95.8 149.4 94.2 53.5 87.1 97.2 148.7 65.4 132.6 162.0 186.0 27.7 26.4 63.0 50.5 194.9 62.6 89.8 107.7 18.3 243.4 546.4 514.6 161.0 143.3 39.6 40.0 28.5 1.8 249.2 138.4 28.0 146.0 7.8 44.9 51.2 5.3 6.1 186.1 261.4 138.2 990.2 88.0 39.9 142.2 72.0 23.6 38.6 58.4 255.8 1.1 185.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.8 0.4 0.0 0.0 0.5 0.3 0.6 0.0 0.0 0.5 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.8 0.0 0.1 0.1 0.0 0.2 0.0 1.7 0.0 0.0 140.6 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.4 0.8 101.2 0.0 0.0 5.3 95.8 94.2 97.2 148.7 89.8 107.7 161.0 143.3 138.4 138.2 142.2 185.8 13.8 12.8 22.1 0.0 17.1 6.2 2.1 0.0 1.8 1.2 4.9 23.1 5.5 24.3 10.5 3.7 0.0 6.6 2.7 0.6 0.0 0.0 3.3 0.1 0.2 65.9 0.0 32.8 0.1 0.0 9.6 5.9 0.0 0.1 11.4 0.1 52.1 26.0 1451.0 0.0 0.1 0.0 0.0 4559.7 92.1 7.8 8.4 1747.2 0.0 34.7 5.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 2.3 1.0 0.3 1.1 3.6 3.9 59.2 4.0 3.2 0.4 0.9 5.7 4.5 9.6 6.1 0.2 0.0 1.5 C1QC C1QG ENSG00000159189 "Complement C1q C chain" P02747 1 22643633-22648110 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 950.7" "Group enriched" "Detected in many" 7 "Hofbauer cells: 1356.5;Kupffer cells: 2134.6;Macrophages: 1040.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "intermediate monocyte: 57.2" "Lineage enriched" "Detected in single" 541 "monocytes: 57.2" "Cell line enhanced" "Detected in some" "NB-4: 1.0;RPMI-8226: 2.6;U-266/70: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001471, CAB009828" Supported "Secreted to blood" NA NA 513000000 2100000000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009828: AB_2067541, HPA001471: AB_1078553" "unprognostic (2.97e-1)" "unprognostic (6.80e-2)" "unprognostic (2.40e-2)" "unprognostic (1.84e-1)" "unprognostic (7.40e-2)" "unprognostic (2.38e-1)" "unprognostic (1.98e-1)" "unprognostic (1.40e-1)" "unprognostic (1.66e-2)" "unprognostic (7.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (1.06e-1)" "unprognostic (1.63e-3)" "unprognostic (2.21e-2)" "unprognostic (3.73e-2)" 285.2 196.0 60.1 159.7 58.6 43.5 70.5 64.8 97.1 51.9 90.6 133.2 179.9 36.3 13.5 55.3 67.4 155.4 58.6 54.9 75.5 41.2 169.6 290.8 370.2 124.7 105.4 32.1 37.5 22.1 39.6 204.9 105.0 37.8 91.3 3.9 51.6 44.5 12.9 18.3 195.7 164.7 100.4 950.7 94.8 33.9 106.0 75.7 29.2 31.8 50.7 191.8 24.6 159.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 1.0 0.2 0.0 0.0 0.6 0.2 2.6 0.0 0.0 0.4 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 1.0 0.0 0.1 0.1 0.1 0.0 0.0 1.3 0.0 0.0 57.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.4 0.0 0.0 1.2 60.1 58.6 64.8 97.1 54.9 75.5 124.7 105.4 105.0 100.4 106.0 159.3 13.4 6.4 5.2 0.3 13.7 8.9 1.1 0.0 2.8 0.6 4.9 24.5 1.6 15.7 3.1 0.0 0.0 5.8 2.3 0.4 0.0 0.0 3.2 0.0 0.1 34.5 0.0 27.2 0.0 0.2 9.5 4.4 0.0 0.1 5.1 0.1 25.4 6.6 1356.5 0.0 0.1 0.1 0.0 2134.6 202.4 3.6 6.2 1040.7 7.2 29.0 23.6 0.4 0.0 0.0 0.0 0.0 1.1 1.2 0.9 0.4 0.0 0.4 0.7 0.6 46.0 2.5 1.8 0.4 0.8 3.3 6.5 9.9 3.5 0.0 0.0 0.7 CAPG "AFCP, MCP" ENSG00000042493 "Capping actin protein, gelsolin like" P40121 2 85394753-85418432 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 548.8;Hofbauer cells: 1107.4;Macrophages: 432.1;monocytes: 432.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 1136.5;classical monocyte: 1139.3;eosinophil: 712.7;intermediate monocyte: 431.6;memory B-cell: 575.6;myeloid DC: 1363.2;naive B-cell: 516.8;NK-cell: 605.5;plasmacytoid DC: 959.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 563.6;HMC-1: 972.7;SK-MEL-30: 722.2;THP-1: 513.5;U-937: 569.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018843, HPA019080, HPA019092" Enhanced Enhanced Nucleoplasm Yes No 5400000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "HPA018843: AB_2669948, HPA019080: AB_1845979, HPA019092: AB_1845980" "unprognostic (2.82e-2)" "unprognostic (1.37e-1)" "unprognostic (8.80e-2)" "unprognostic (1.28e-2)" "unprognostic (4.37e-2)" "unprognostic (7.52e-2)" "prognostic unfavorable (3.22e-5)" "unprognostic (8.83e-2)" "unprognostic (3.22e-2)" "unprognostic (1.54e-1)" "unprognostic (5.70e-3)" "unprognostic (1.75e-1)" "prognostic favorable (2.96e-4)" "unprognostic (1.45e-1)" "unprognostic (7.68e-2)" "unprognostic (5.30e-3)" "unprognostic (7.89e-3)" 92.4 26.3 42.8 82.4 44.2 159.3 94.9 46.3 79.6 119.1 37.5 56.9 30.3 50.0 46.2 289.5 48.7 44.4 19.2 41.7 51.1 201.1 8.9 175.7 117.9 60.2 46.3 19.7 44.9 151.7 27.2 26.1 57.2 76.5 42.9 4.2 111.8 38.0 16.5 219.9 54.2 24.5 57.5 46.2 94.4 26.0 66.1 58.0 162.3 5.8 109.5 97.1 174.8 79.4 165.5 75.9 0.7 6.9 50.2 102.8 83.7 59.6 6.1 51.2 49.8 9.4 563.6 28.1 96.6 116.0 64.0 181.1 0.2 113.7 23.0 142.0 4.4 74.3 128.0 29.3 40.6 44.8 972.7 93.8 80.5 53.8 70.3 3.6 37.5 143.8 8.2 60.1 38.1 150.1 101.3 414.8 23.2 166.5 112.8 87.3 13.3 11.8 220.6 77.7 0.8 1.4 86.9 128.4 722.2 44.2 40.0 513.5 148.7 111.6 26.8 4.6 2.4 1.4 6.2 10.3 259.5 569.5 1.5 1136.5 1139.3 712.7 12.2 431.6 39.2 575.6 107.8 41.1 1363.2 516.8 30.5 13.9 162.9 605.5 131.3 959.7 122.1 977.9 42.8 44.2 46.3 79.6 41.7 51.1 60.2 46.3 57.2 57.5 66.1 79.4 6.6 19.2 24.5 3.3 84.7 121.2 167.5 265.0 60.9 0.8 86.8 70.4 1.3 51.5 119.6 316.3 0.0 34.3 91.5 211.0 211.3 113.8 4.1 33.0 10.3 16.2 28.8 16.0 0.2 91.5 324.0 34.7 124.9 63.9 548.8 1.2 3.6 1.1 1107.4 1.7 0.2 55.9 50.8 141.6 337.2 15.2 46.9 432.1 147.7 1.0 432.4 43.6 11.3 0.5 0.1 405.8 205.4 22.6 17.2 106.0 74.1 168.5 48.8 1.7 13.1 2.0 54.0 9.6 33.1 167.4 169.5 35.7 101.9 0.9 83.9 253.1 CD300LF "CD300f, CLM1, IGSF13, IREM1, NKIR" ENSG00000186074 "CD300 molecule like family member f" Q8TDQ1 17 74694311-74712978 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.0;lung: 17.7;lymphoid tissue: 28.9" "Group enriched" "Detected in some" 5 "granulocytes: 22.8;Hofbauer cells: 20.6;Kupffer cells: 33.2;Macrophages: 47.0;monocytes: 39.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 234.2" "Group enriched" "Detected in many" 43 "dendritic cells: 63.8;granulocytes: 234.2;monocytes: 193.0" "Group enriched" "Detected in some" 6 "THP-1: 25.6;U-937: 48.6" "Low region specificity" "Detected in some" HPA013712 Supported NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA013712: AB_2668874" "unprognostic (6.51e-2)" "unprognostic (1.49e-3)" "unprognostic (3.81e-2)" "unprognostic (4.00e-2)" "unprognostic (8.51e-2)" "unprognostic (6.74e-2)" "unprognostic (1.79e-1)" "unprognostic (3.17e-3)" "unprognostic (1.53e-2)" "unprognostic (1.77e-1)" "unprognostic (9.81e-2)" "unprognostic (2.41e-1)" "unprognostic (1.95e-1)" "unprognostic (9.60e-2)" "unprognostic (4.14e-2)" "unprognostic (7.75e-2)" "unprognostic (4.79e-2)" 1.9 0.6 0.9 13.5 1.1 27.0 0.8 6.2 4.2 1.3 0.7 3.4 3.8 0.6 0.2 0.5 0.7 2.7 0.5 1.0 1.3 0.6 2.2 17.7 8.8 2.6 1.8 0.2 0.5 0.4 0.4 1.7 2.4 0.7 3.5 0.2 0.8 0.5 0.3 0.1 3.6 3.3 1.7 28.9 1.6 0.4 2.8 2.0 0.4 0.8 5.4 3.0 0.4 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.9 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 2.2 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.6 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 48.6 0.0 48.4 96.3 234.2 0.3 165.3 0.5 0.2 0.1 0.2 63.8 0.2 0.2 0.1 74.7 3.7 193.0 6.7 0.4 44.8 0.9 1.1 6.2 4.2 1.0 1.3 2.6 1.8 2.4 1.7 2.8 3.2 0.1 0.0 6.4 0.0 1.3 0.1 0.0 0.1 0.0 0.4 0.1 0.4 0.2 1.5 3.3 0.0 2.1 0.1 2.7 0.1 0.0 0.0 0.3 0.0 0.0 0.8 0.0 1.7 2.7 0.0 0.2 0.3 0.0 0.0 22.8 0.0 1.1 0.3 20.6 0.0 2.1 0.1 0.0 33.2 0.7 0.2 0.0 47.0 0.0 3.7 39.9 0.0 1.0 0.5 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 CD33 "FLJ00391, p67, SIGLEC-3, SIGLEC3" ENSG00000105383 "CD33 molecule" P20138 19 51225064-51243860 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.4;lymphoid tissue: 23.9" "Group enriched" "Detected in some" 6 "granulocytes: 76.0;Hofbauer cells: 78.8;Kupffer cells: 131.2;Langerhans cells: 41.4;Macrophages: 53.5;monocytes: 65.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 166.5;intermediate monocyte: 122.0;myeloid DC: 213.5;non-classical monocyte: 57.8" "Group enriched" "Detected in many" 9 "dendritic cells: 213.5;monocytes: 166.5" "Cell line enhanced" "Detected in some" "HEL: 86.1;HL-60: 115.6;HMC-1: 82.4;NB-4: 55.2;RPMI-8226: 62.5;THP-1: 67.0;U-937: 84.1" "CAB011442, HPA035832, HPA064807, CAB079996" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 3400000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Plasma membrane" "CAB011442: , CAB079996: , HPA035832: AB_2674808, HPA064807: AB_2685356" "unprognostic (1.18e-2)" "unprognostic (1.45e-2)" "unprognostic (2.80e-2)" "unprognostic (7.14e-2)" "unprognostic (3.71e-1)" "unprognostic (9.43e-2)" "unprognostic (2.59e-1)" "unprognostic (5.90e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-1)" "unprognostic (2.53e-1)" "unprognostic (6.28e-2)" "unprognostic (6.88e-4)" "unprognostic (7.79e-2)" "unprognostic (3.35e-2)" "unprognostic (6.49e-2)" "unprognostic (1.67e-1)" 7.9 3.4 1.1 11.2 1.2 32.4 2.5 1.5 1.6 3.0 2.5 3.2 3.3 1.7 1.3 2.0 2.5 6.6 2.0 1.1 1.8 1.4 5.5 12.6 10.1 2.5 1.6 1.4 1.4 1.2 0.9 6.9 2.4 1.4 4.2 0.2 1.8 2.6 0.9 2.7 4.4 7.1 1.9 23.9 2.3 1.0 2.3 3.5 0.9 0.8 3.5 6.2 1.3 3.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.2 0.0 5.5 0.4 0.0 1.3 0.3 0.0 0.2 0.0 0.1 0.1 86.1 0.3 0.0 0.0 115.6 82.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 16.2 21.2 0.2 0.0 0.0 55.2 0.2 0.0 25.9 0.0 4.4 62.5 0.4 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 67.0 0.7 14.0 1.1 1.8 0.1 0.3 7.6 0.2 9.6 84.1 0.4 17.9 166.5 11.0 0.3 122.0 0.4 0.1 0.2 0.5 213.5 0.4 0.3 0.2 20.5 15.5 57.8 6.3 1.1 77.8 1.1 1.2 1.5 1.6 1.1 1.8 2.5 1.6 2.4 1.9 2.3 3.6 0.7 0.0 6.7 0.0 1.0 1.8 0.5 0.0 0.0 0.2 1.4 0.4 0.8 0.0 0.6 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.7 0.1 0.1 3.0 0.0 4.2 0.0 0.0 0.5 1.1 0.0 0.1 76.0 0.1 5.3 0.7 78.8 0.0 0.0 0.0 0.0 131.2 41.4 1.7 0.3 53.5 1.8 11.2 65.0 0.2 1.0 0.5 0.2 0.0 0.0 0.0 0.3 0.4 0.0 0.2 0.7 0.6 0.0 1.1 0.3 0.7 0.5 0.0 1.0 0.8 2.5 0.1 0.0 0.4 CD68 "DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1" ENSG00000129226 "CD68 molecule" P34810 17 7579491-7582111 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 358.0;lymphoid tissue: 370.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1820.4;Kupffer cells: 701.2;Langerhans cells: 341.5;Macrophages: 791.2;Proximal enterocytes: 335.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3255.5;intermediate monocyte: 3655.9;non-classical monocyte: 3740.6" "Group enriched" "Detected in all" 11 "dendritic cells: 1378.6;monocytes: 3740.6" "Cell line enhanced" "Detected in all" "ASC diff: 472.0;U-87 MG: 751.0" "Low region specificity" "Detected in all" "CAB000051, CAB000066, HPA048982, CAB072861, CAB072862" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "CAB000051: AB_2314148, CAB000066: AB_2074844, CAB072861: AB_2665705, CAB072862: AB_2665706, HPA048982: AB_2680587" "unprognostic (2.16e-2)" "unprognostic (1.47e-2)" "unprognostic (6.46e-2)" "unprognostic (1.49e-3)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (4.75e-4)" "unprognostic (2.83e-2)" "unprognostic (1.31e-1)" "unprognostic (6.85e-2)" "unprognostic (1.04e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (1.14e-5)" "unprognostic (1.58e-1)" "unprognostic (8.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.65e-2)" 139.6 78.3 10.4 236.1 9.8 266.2 72.6 11.2 33.4 77.8 14.6 88.8 279.5 26.7 9.0 126.4 43.1 161.1 38.9 8.2 26.7 50.6 156.7 358.0 217.3 45.5 31.2 19.4 22.1 14.2 8.9 173.1 36.0 13.1 91.9 4.8 52.6 19.8 23.0 24.8 240.2 79.0 16.1 370.7 87.5 15.2 58.5 44.2 22.7 21.3 84.2 149.3 50.6 31.6 243.4 48.6 3.2 3.5 472.0 177.6 2.1 75.6 203.9 97.8 113.4 10.1 71.3 2.9 84.2 220.8 174.6 10.6 1.2 47.6 65.9 2.2 9.0 38.8 13.2 59.0 42.0 19.2 207.8 57.1 9.8 205.4 150.4 162.6 26.3 4.3 15.7 24.2 95.5 2.2 1.7 17.2 2.8 63.1 36.0 3.3 4.5 144.4 20.9 10.9 1.6 3.0 63.2 31.3 72.1 2.2 1.6 146.1 82.4 123.7 8.0 125.7 100.1 1.4 2.1 1.9 751.0 46.4 64.0 243.5 3255.5 21.4 9.1 3655.9 11.1 80.2 4.1 6.2 817.3 59.0 5.8 5.1 219.4 18.7 3740.6 1378.6 6.5 3324.3 10.4 9.8 11.2 33.4 8.2 26.7 45.5 31.2 36.0 16.1 58.5 31.6 10.4 0.0 19.7 1.3 20.5 15.7 39.0 58.8 3.4 0.2 7.2 9.8 0.0 12.8 53.2 5.5 0.0 8.9 110.3 22.5 5.9 82.1 0.8 8.3 11.3 15.9 4.9 6.6 0.3 156.8 58.1 45.6 29.6 18.7 43.6 0.9 16.4 23.9 1820.4 0.0 0.4 15.8 16.2 701.2 341.5 2.1 6.5 791.2 39.2 5.6 179.2 0.3 7.2 0.0 0.1 121.0 86.1 1.9 8.5 33.3 335.3 50.2 20.6 1.0 26.3 8.7 11.7 0.5 1.2 12.4 14.3 33.4 10.8 0.5 28.9 99.9 COMMD9 "FLJ31106, HSPC166" ENSG00000110442 "COMM domain containing 9" Q9P000 11 36269284-36289449 "Predicted intracellular proteins" "Ion transport, Sodium transport, Transcription, Transcription regulation, Transport, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009142 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 18: U-2197 - ECM organization" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "Golgi apparatus, Cytosol" "HPA009142: AB_1847105" "unprognostic (1.56e-2)" "unprognostic (4.75e-3)" "unprognostic (7.57e-2)" "unprognostic (4.40e-3)" "unprognostic (1.91e-1)" "unprognostic (2.12e-1)" "unprognostic (1.16e-3)" "unprognostic (2.62e-1)" "unprognostic (6.15e-2)" "prognostic favorable (8.54e-4)" "unprognostic (4.94e-2)" "unprognostic (2.40e-1)" "unprognostic (6.08e-3)" "unprognostic (7.24e-2)" "unprognostic (1.71e-1)" "unprognostic (7.31e-3)" "unprognostic (1.88e-1)" 26.8 32.1 33.8 21.8 34.1 50.8 24.3 35.1 36.7 17.2 29.6 19.6 21.1 14.1 25.1 24.9 20.3 20.5 31.1 33.8 33.8 38.7 36.6 26.8 26.0 34.2 34.4 19.4 26.4 27.4 23.2 24.8 33.9 14.0 24.2 20.3 21.9 13.3 64.2 27.1 20.2 21.9 36.9 26.8 19.7 14.9 36.0 30.6 25.1 61.7 32.0 20.6 16.6 39.1 28.8 33.4 36.1 38.2 54.5 37.8 20.0 33.6 42.6 74.7 69.8 27.3 23.9 33.0 32.5 67.1 57.5 41.4 64.0 45.2 69.6 39.9 75.2 18.2 57.6 48.0 51.0 71.6 52.3 48.0 49.5 40.9 25.0 38.5 62.2 43.3 45.7 34.7 59.4 36.9 47.9 49.6 38.5 55.6 70.3 52.1 81.7 38.9 78.6 26.6 44.1 49.2 47.9 47.1 43.6 29.2 102.7 27.0 41.9 45.0 34.4 107.9 49.8 24.3 53.2 37.2 51.8 66.4 44.0 85.6 376.6 173.7 91.4 359.0 86.8 130.7 87.5 88.4 383.6 138.3 99.8 83.4 42.7 94.8 300.9 145.8 114.5 315.2 33.8 34.1 35.1 36.7 33.8 33.8 34.2 34.4 33.9 36.9 36.0 39.1 26.9 22.4 29.4 2.6 27.0 15.3 12.7 37.4 13.1 16.6 25.6 38.7 29.9 12.8 20.2 18.4 10.4 43.2 28.3 16.9 78.2 70.1 9.5 13.2 20.3 22.8 25.7 23.1 9.4 46.4 52.9 21.2 11.7 17.0 19.0 25.6 15.4 17.1 105.1 5.0 8.7 20.4 34.6 59.5 35.6 28.9 17.7 57.5 24.9 1.9 61.3 36.3 33.0 4.5 8.8 46.5 17.7 11.7 10.4 4.9 30.3 62.5 8.5 22.9 13.1 12.3 22.8 32.8 33.3 19.6 21.6 24.9 19.2 28.4 24.6 12.0 CREG1 CREG ENSG00000143162 "Cellular repressor of E1A stimulated genes 1" O75629 1 167529117-167553805 "Predicted secreted proteins" "Growth regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 545.7;Kupffer cells: 559.7;monocytes: 322.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 55.4;classical monocyte: 128.4;eosinophil: 75.7;intermediate monocyte: 75.7;myeloid DC: 89.9;neutrophil: 43.7;non-classical monocyte: 72.3" "Group enriched" "Detected in all" 6 "dendritic cells: 89.9;granulocytes: 75.7;monocytes: 128.4" "Cell line enhanced" "Detected in all" "RPMI-8226: 1237.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056390 Approved Vesicles,Microtubules "Secreted to blood" NA NA 520000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Microtubules Vesicles "HPA056390: AB_2683113" "unprognostic (3.25e-1)" "unprognostic (2.00e-1)" "unprognostic (1.91e-1)" "unprognostic (9.65e-3)" "unprognostic (4.64e-2)" "unprognostic (2.35e-2)" "unprognostic (1.55e-1)" "unprognostic (5.02e-2)" "unprognostic (2.07e-3)" "unprognostic (8.54e-2)" "unprognostic (8.65e-2)" "unprognostic (1.21e-1)" "unprognostic (8.24e-3)" "unprognostic (2.99e-1)" "unprognostic (4.63e-2)" "unprognostic (3.78e-3)" "unprognostic (3.16e-1)" 130.5 127.7 37.5 79.0 41.1 125.9 109.7 39.0 45.9 76.8 47.8 77.1 60.3 61.8 109.7 91.7 70.9 128.2 82.2 36.5 40.4 132.1 295.2 99.1 98.9 46.0 39.1 84.2 70.7 75.4 64.8 110.8 44.4 62.9 82.7 80.0 104.5 74.6 71.4 109.8 63.0 77.9 45.7 136.9 61.4 50.1 49.3 35.5 125.8 78.2 63.5 116.3 63.3 61.2 93.5 41.5 21.1 43.5 325.8 89.8 53.0 39.2 17.8 30.7 39.8 67.8 104.4 101.7 112.2 43.6 57.2 143.3 24.3 84.9 20.9 140.3 82.3 41.5 31.1 37.9 111.5 93.6 295.2 94.5 250.5 35.6 38.7 42.7 10.3 35.9 218.5 405.0 42.6 39.2 19.6 95.9 22.8 214.0 63.9 32.5 58.8 1237.2 54.7 64.9 14.0 25.7 98.1 132.8 112.8 70.1 175.5 252.7 19.1 8.0 39.6 126.2 25.9 79.4 168.4 67.7 131.6 96.0 16.3 55.4 128.4 75.7 5.1 75.7 8.0 4.3 7.5 6.5 89.9 2.1 16.6 8.8 43.7 11.0 72.3 6.2 3.9 57.6 37.5 41.1 39.0 45.9 36.5 40.4 46.0 39.1 44.4 45.7 49.3 61.2 44.7 35.3 90.1 5.9 15.3 44.1 49.1 23.1 56.9 17.9 61.7 63.8 55.7 65.8 32.2 55.2 89.6 91.5 18.3 15.6 23.5 36.0 27.6 33.9 19.3 34.2 29.3 124.8 24.7 39.7 41.7 78.4 21.9 64.1 29.9 62.0 48.2 90.3 545.7 15.2 22.1 44.5 14.2 559.7 57.6 27.4 43.5 213.8 24.9 26.2 322.8 30.5 6.2 10.1 14.6 21.0 31.5 28.6 27.8 34.0 46.3 60.6 18.5 31.5 13.1 43.2 40.8 65.5 42.0 86.3 51.1 126.7 17.3 38.9 50.4 44.0 CSTB "CST6, EPM1, PME, STFB" ENSG00000160213 "Cystatin B" P04080 21 43772511-43776330 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "esophagus: 11304.7" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 5910.7;Club cells: 4352.8;Hofbauer cells: 2827.7;Squamous epithelial cells: 4910.2;Urothelial cells: 3198.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 2798.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017380, CAB047320, HPA058557" Enhanced Supported Nucleoli,Cytosol NA NA 8700000 "Cluster 51: Monocytes - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol Nucleoli "CAB047320: , HPA017380: AB_1847414, HPA058557: AB_2683755" "unprognostic (1.69e-1)" "unprognostic (3.35e-1)" "unprognostic (2.09e-1)" "unprognostic (3.05e-2)" "unprognostic (3.05e-2)" "unprognostic (5.92e-2)" "prognostic unfavorable (6.66e-5)" "unprognostic (1.90e-1)" "unprognostic (1.32e-1)" "unprognostic (2.14e-1)" "unprognostic (1.27e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (2.10e-4)" "unprognostic (3.63e-1)" "unprognostic (4.88e-1)" "unprognostic (4.24e-2)" "unprognostic (1.24e-1)" 224.3 165.6 254.1 141.6 253.6 73.8 161.9 255.4 314.6 585.8 275.2 243.8 122.9 90.1 175.0 11304.7 154.1 150.7 192.2 252.8 263.0 144.7 189.4 290.1 176.4 258.4 257.8 136.1 116.2 154.4 70.1 132.1 259.6 137.3 194.7 78.9 738.3 138.6 100.1 256.9 135.6 110.4 257.5 125.8 249.9 71.7 262.8 268.2 147.9 197.4 1484.9 611.8 1001.9 262.9 1573.6 495.5 146.3 188.1 874.5 742.6 379.6 310.1 431.0 230.7 230.6 401.6 868.6 123.0 245.8 570.1 1814.0 260.5 384.4 405.7 153.5 529.0 388.4 332.4 385.3 473.8 753.0 85.5 267.1 754.5 439.6 621.2 314.7 389.3 331.2 111.8 276.9 681.1 359.7 431.4 100.1 267.6 336.0 1052.6 791.5 169.7 80.5 1472.0 669.1 2798.2 141.8 121.6 420.2 229.2 928.8 75.7 210.4 214.0 426.3 347.7 162.7 305.5 211.8 148.5 347.4 251.1 1432.5 430.2 242.3 390.1 505.5 313.1 242.9 840.3 224.5 198.5 315.4 255.4 766.1 172.7 221.0 217.6 445.6 152.4 1322.9 93.4 406.9 475.2 254.1 253.6 255.4 314.6 252.8 263.0 258.4 257.8 259.6 257.5 262.8 262.9 210.1 176.3 298.4 43.4 140.5 385.3 460.6 5910.7 191.2 69.8 317.8 345.1 105.7 268.8 4352.8 415.6 35.5 310.4 126.5 803.9 538.1 588.4 10.4 388.8 205.1 307.8 239.3 61.4 17.0 488.2 1199.4 238.6 297.7 458.8 228.2 131.5 250.6 464.5 2827.7 67.3 18.4 308.6 1462.8 483.4 1256.2 40.8 381.1 806.9 471.4 24.4 915.9 160.6 255.4 11.1 32.4 810.9 735.6 330.2 167.7 674.3 524.9 469.9 1997.3 72.9 118.3 86.5 320.0 33.7 111.7 4910.2 596.0 402.5 202.8 170.9 367.2 3198.3 CTSB ENSG00000164733 "Cathepsin B" P07858 8 11842524-11869533 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2744.5;Kupffer cells: 1774.9;Macrophages: 1224.3" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 1446.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 390.6;classical monocyte: 610.1;intermediate monocyte: 467.3;myeloid DC: 287.4;non-classical monocyte: 307.6;plasmacytoid DC: 410.1" "Group enriched" "Detected in all" 6 "dendritic cells: 410.1;granulocytes: 390.6;monocytes: 610.1" "Cell line enhanced" "Detected in all" "BJ hTERT+: 1607.5;fHDF/TERT166: 1436.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000457, HPA018156, HPA048998" Enhanced Supported Nucleoli,Vesicles "Secreted to blood" NA NA 100000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoli "CAB000457: , HPA018156: AB_1846069, HPA048998: " "unprognostic (5.74e-2)" "unprognostic (4.32e-2)" "unprognostic (1.38e-2)" "unprognostic (2.17e-2)" "unprognostic (2.98e-3)" "unprognostic (5.96e-2)" "unprognostic (1.36e-2)" "unprognostic (1.07e-1)" "unprognostic (2.82e-2)" "unprognostic (1.06e-1)" "unprognostic (7.61e-2)" "unprognostic (8.30e-2)" "unprognostic (2.85e-1)" "unprognostic (7.39e-2)" "unprognostic (4.12e-2)" "prognostic favorable (5.76e-4)" "prognostic unfavorable (9.02e-4)" 443.9 304.5 65.6 399.7 71.2 87.0 249.0 65.9 77.2 583.2 101.0 312.4 120.8 379.2 116.9 421.6 368.4 230.6 447.0 64.7 95.5 420.6 497.2 428.9 289.6 100.4 90.8 169.1 135.4 79.6 156.8 253.2 107.4 255.5 159.3 33.6 437.3 156.6 237.4 184.7 260.2 316.1 91.9 521.1 194.3 33.2 204.5 60.9 1150.7 99.3 104.0 431.9 477.8 159.2 66.6 283.4 4.0 94.9 657.3 754.5 128.3 885.0 1607.5 258.4 299.5 10.3 294.4 1.5 32.2 1436.1 419.3 279.5 65.3 157.1 195.6 25.9 52.6 58.8 10.0 397.1 479.2 7.7 73.7 296.4 532.2 327.2 427.3 611.5 33.4 20.2 81.7 260.7 194.6 62.5 6.5 23.1 16.3 839.7 91.3 33.6 39.3 202.7 2.6 121.1 4.9 68.6 165.1 68.6 514.6 110.1 97.8 68.7 922.4 766.5 111.9 129.9 259.3 182.7 178.5 4.8 432.5 22.9 249.4 390.6 610.1 90.6 26.3 467.3 35.4 44.1 79.0 31.5 287.4 38.8 48.3 21.5 97.8 31.3 307.6 410.1 78.7 703.7 65.6 71.2 65.9 77.2 64.7 95.5 100.4 90.8 107.4 91.9 204.5 159.2 87.7 109.0 171.4 17.6 54.8 54.7 441.6 563.2 54.7 55.2 94.1 74.5 320.1 165.8 331.7 114.0 41.7 279.4 122.4 147.9 27.4 294.6 15.6 105.8 240.1 163.0 154.7 210.2 36.2 238.2 341.7 155.0 44.4 183.5 179.4 105.9 204.2 239.5 2744.5 58.9 42.8 94.2 158.7 1774.9 436.5 18.5 76.4 1224.3 161.9 70.3 373.1 117.4 24.7 19.1 12.9 363.9 154.0 92.9 47.3 295.5 198.6 351.8 180.8 40.0 39.5 39.4 149.9 10.8 21.0 160.3 40.5 649.6 56.0 32.1 139.6 321.4 CTSD "CLN10, CPSD" ENSG00000117984 "Cathepsin D" P07339 11 1752752-1764573 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Alzheimer disease, Cancer-related genes, Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1475.9;Hofbauer cells: 3763.5;Macrophages: 1512.6;Proximal enterocytes: 1699.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CAPAN-2: 2596.6;hTERT-RPE1: 2780.1;SK-BR-3: 2488.5" "CAB000109, HPA003001" Supported "Secreted to blood" NA NA 370000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "CAB000109: , HPA003001: AB_1078404" "unprognostic (9.95e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.46e-4)" "unprognostic (1.09e-1)" "unprognostic (1.71e-3)" "unprognostic (2.65e-2)" "unprognostic (9.40e-3)" "unprognostic (1.11e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-3)" "unprognostic (1.59e-1)" "unprognostic (1.86e-2)" "prognostic favorable (4.93e-5)" "unprognostic (8.98e-2)" "unprognostic (3.39e-2)" "unprognostic (2.13e-2)" "unprognostic (1.60e-1)" 318.6 734.6 147.0 204.9 181.9 499.0 244.0 186.0 156.5 270.8 672.7 298.0 387.6 170.7 82.8 319.4 171.6 438.4 444.1 187.8 223.6 691.6 464.8 539.6 241.0 247.6 206.6 130.7 284.8 137.3 131.5 180.7 228.6 138.2 153.4 48.3 422.1 231.7 590.3 340.9 398.3 105.0 188.9 442.0 287.2 88.9 334.4 78.1 182.1 178.2 123.1 296.4 307.5 367.1 204.6 578.9 51.4 246.2 586.5 206.3 112.1 149.4 362.2 161.8 182.8 147.5 2596.6 49.2 376.8 285.8 1265.6 1072.2 63.7 142.6 35.8 206.7 222.9 70.4 92.5 196.5 736.2 171.4 787.7 350.9 621.6 82.5 136.9 2780.1 128.2 62.1 89.2 267.6 263.3 832.6 47.0 110.9 153.1 719.7 247.9 62.5 72.5 191.2 586.6 610.8 84.2 94.8 173.3 2488.5 535.0 68.6 1022.8 232.6 170.3 556.8 92.9 79.0 216.7 432.0 382.3 26.8 867.7 468.6 509.6 211.2 578.7 170.1 156.5 309.9 90.6 28.8 72.1 110.3 144.5 18.8 82.5 107.4 319.5 192.3 265.2 120.3 89.2 489.1 147.0 181.9 186.0 156.5 187.8 223.6 247.6 206.6 228.6 188.9 334.4 367.1 139.3 112.2 228.6 48.3 62.8 72.0 223.5 473.2 71.7 168.6 108.9 113.8 251.9 314.5 459.5 548.1 110.5 211.7 156.1 1475.9 109.5 911.4 3.3 118.1 67.4 128.3 159.6 132.6 18.3 370.1 165.0 157.0 237.5 203.4 474.3 119.4 695.7 678.9 3763.5 264.2 25.2 418.2 498.5 1187.8 67.5 14.6 108.4 1512.6 227.7 20.6 382.6 179.0 256.4 27.2 42.2 392.3 832.5 128.2 122.5 111.7 1699.4 311.8 270.3 102.1 111.7 70.7 135.2 26.6 63.5 141.2 82.1 471.3 155.0 96.0 399.1 357.8 CTSZ CTSX ENSG00000101160 "Cathepsin Z" Q9UBR2 20 58985686-59008238 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1078.9;Langerhans cells: 983.5;Macrophages: 652.3;monocytes: 723.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 542.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025114, HPA049876, HPA053504" Supported Supported Vesicles "Intracellular and membrane" NA NA 88000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Vesicles "CAB025114: , HPA049876: AB_2680927, HPA053504: AB_2682172" "unprognostic (7.30e-2)" "unprognostic (3.98e-2)" "unprognostic (4.07e-2)" "unprognostic (1.11e-3)" "unprognostic (8.25e-3)" "unprognostic (1.15e-1)" "unprognostic (4.12e-2)" "unprognostic (6.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.22e-1)" "unprognostic (1.33e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (5.72e-5)" "unprognostic (1.96e-1)" "unprognostic (6.92e-2)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" 178.1 117.8 18.9 208.8 21.8 99.8 137.0 20.5 32.0 92.1 59.6 173.8 215.4 87.3 13.4 53.1 88.9 89.4 152.6 15.3 33.9 125.6 356.4 233.3 271.5 31.6 23.5 71.0 89.4 91.8 112.5 118.7 27.9 87.8 77.1 4.1 181.0 66.3 58.7 58.5 226.0 97.9 26.2 234.4 88.2 24.6 47.2 57.1 122.3 54.6 91.3 146.3 69.0 45.4 205.4 139.8 1.1 1.1 114.2 124.2 106.5 291.0 225.4 187.4 152.3 231.6 324.6 96.5 213.9 542.1 0.5 160.1 51.4 257.5 30.2 362.1 13.6 80.3 169.0 0.8 137.3 9.0 331.0 130.9 127.8 83.1 62.4 34.8 281.3 1.1 74.0 48.7 90.0 1.1 1.3 70.6 11.5 43.5 158.2 2.9 0.4 135.7 86.3 25.5 2.7 1.7 222.4 258.4 0.8 19.5 131.9 148.4 420.5 1.4 161.8 209.0 2.0 253.7 172.0 18.2 2.8 207.9 0.4 1.2 1.5 1.6 0.6 1.4 0.4 1.1 0.6 0.4 1.1 1.4 0.7 0.8 1.6 0.5 2.9 1.8 0.3 0.7 18.9 21.8 20.5 32.0 15.3 33.9 31.6 23.5 27.9 26.2 47.2 45.4 132.1 16.0 5.3 5.9 119.8 50.3 64.5 33.8 24.5 6.7 67.4 99.6 21.7 62.9 14.1 71.7 0.0 38.2 104.8 303.6 23.5 176.0 3.5 52.9 47.7 82.2 27.1 63.3 5.3 42.4 104.8 71.5 19.4 71.3 10.8 68.4 62.8 363.0 1078.9 11.8 3.0 56.6 26.4 334.0 983.5 6.0 13.1 652.3 101.4 23.4 723.6 58.6 21.6 2.5 2.5 82.6 217.5 13.9 96.3 50.6 339.8 90.0 18.8 5.0 46.0 67.5 74.5 3.7 4.8 14.5 41.5 41.3 33.4 3.3 99.7 52.7 CYP27A1 "CP27, CTX, CYP27" ENSG00000135929 "Cytochrome P450 family 27 subfamily A member 1" Q02318 2 218781749-218815293 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "liver: 594.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 404.3;Hofbauer cells: 148.9;Proximal enterocytes: 206.3" "Group enriched" "Detected in all" 4 "liver cancer: 176.9;melanoma: 85.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 151.5;neutrophil: 126.3" "Group enriched" "Detected in many" 21 "granulocytes: 126.3;monocytes: 151.5" "Cell line enhanced" "Detected in many" "Hep G2: 299.6;HSkMC: 54.7;RPTEC TERT1: 78.5;SK-MEL-30: 103.6;WM-115: 42.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059155 Enhanced Approved Mitochondria,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Mitochondria Cytosol "HPA059155: AB_2683933" "prognostic favorable (1.05e-4)" "unprognostic (4.21e-2)" "unprognostic (2.34e-1)" "unprognostic (1.83e-3)" "unprognostic (3.71e-3)" "unprognostic (1.31e-2)" "prognostic favorable (8.62e-6)" "unprognostic (6.04e-2)" "unprognostic (1.73e-1)" "unprognostic (4.04e-1)" "unprognostic (1.25e-3)" "unprognostic (8.76e-3)" "unprognostic (1.09e-3)" "unprognostic (1.08e-1)" "unprognostic (7.51e-2)" "unprognostic (1.64e-1)" "unprognostic (1.36e-1)" 23.1 50.3 45.2 15.7 59.0 1.3 21.8 57.0 59.3 27.6 75.6 27.6 77.8 19.8 11.6 11.9 34.0 19.1 30.7 42.2 49.3 46.4 594.4 71.7 24.6 63.0 56.1 32.6 8.3 18.5 29.6 6.2 62.7 41.8 20.7 22.5 40.4 29.5 37.9 17.5 81.9 13.2 50.6 13.0 13.8 12.6 58.8 23.6 12.6 49.2 28.0 24.3 23.2 69.2 0.2 0.0 2.7 0.2 4.6 3.3 0.4 1.9 11.7 3.9 7.8 13.7 0.8 0.0 4.3 7.6 0.2 0.1 0.0 0.0 1.7 1.4 1.0 0.0 0.4 299.6 16.2 0.4 0.3 54.7 0.5 0.1 0.0 12.8 5.9 0.0 0.3 0.1 8.3 0.0 0.0 0.2 2.3 0.3 0.5 0.1 2.4 0.5 78.5 0.2 0.2 0.2 0.1 0.0 103.6 2.4 1.6 2.2 5.9 0.0 0.2 0.1 6.0 0.0 0.0 0.1 0.1 0.3 42.9 0.0 151.5 0.4 0.2 17.1 0.3 0.7 0.2 0.5 6.5 0.0 0.1 0.0 126.3 0.0 1.2 0.8 0.0 44.1 45.2 59.0 57.0 59.3 42.2 49.3 63.0 56.1 62.7 50.6 58.8 69.2 10.6 3.2 28.9 33.6 0.9 5.2 52.4 8.5 21.6 15.3 12.7 18.8 5.1 17.2 11.3 3.7 27.1 0.7 0.5 37.0 9.8 12.1 1.0 12.6 4.3 10.3 24.5 8.4 2.2 12.0 0.7 35.4 2.6 14.8 2.5 1.9 19.6 404.3 148.9 10.1 3.9 20.0 4.1 18.2 5.1 1.0 47.5 104.3 49.8 15.0 92.4 28.7 0.0 26.7 108.5 9.7 44.0 26.7 0.0 43.3 206.3 76.9 21.4 14.1 0.0 12.8 7.2 0.7 0.1 3.2 3.1 1.2 2.3 1.2 30.3 20.4 DLEU7 FLJ44882 ENSG00000186047 "Deleted in lymphocytic leukemia 7" Q6UYE1 13 50519364-50843939 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "brain: 5.0;choroid plexus: 2.3" "Group enriched" "Detected in some" 4 "Bipolar cells: 25.9;Excitatory neurons: 26.8;Inhibitory neurons: 44.9;Kupffer cells: 35.6;Microglial cells: 35.6;Oligodendrocyte precursor cells: 21.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "NTERA-2: 10.4;U-698: 4.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA053750 Uncertain NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA053750: AB_2682249" "unprognostic (3.97e-2)" "unprognostic (2.53e-1)" "unprognostic (7.03e-2)" "unprognostic (9.31e-2)" "unprognostic (3.08e-1)" "unprognostic (1.08e-1)" "unprognostic (4.47e-3)" "unprognostic (1.09e-1)" "unprognostic (1.24e-1)" "unprognostic (8.75e-3)" "unprognostic (1.23e-1)" "unprognostic (1.69e-1)" "unprognostic (5.88e-2)" "unprognostic (1.59e-1)" "unprognostic (4.52e-2)" "unprognostic (1.03e-1)" "unprognostic (1.51e-1)" 0.0 0.1 4.3 0.0 4.3 0.0 0.0 3.5 4.8 0.1 2.3 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.4 3.7 0.1 0.0 0.0 0.0 4.2 4.4 0.0 0.0 0.0 0.1 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 3.9 0.1 0.0 0.4 5.0 0.6 0.3 0.1 0.0 0.0 0.1 4.8 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 10.4 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.2 4.3 4.3 3.5 4.8 4.4 3.7 4.2 4.4 4.0 3.9 5.0 4.8 0.1 0.0 0.5 1.0 0.0 0.0 0.0 0.0 0.0 25.9 0.1 0.3 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.4 0.0 0.0 26.8 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.3 6.8 0.0 44.9 0.0 0.0 35.6 1.4 0.0 0.0 7.1 0.0 35.6 7.6 0.2 0.0 21.1 1.9 0.0 0.0 1.5 0.3 0.0 0.0 0.9 0.0 1.8 0.0 0.5 0.1 0.0 0.4 0.0 0.0 0.3 0.1 0.0 0.1 0.0 DNAJC5B "CSP-beta, MGC26226" ENSG00000147570 "DnaJ heat shock protein family (Hsp40) member C5 beta" Q9UF47 8 66021553-66101245 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 65.4" "Group enriched" "Detected in some" 71 "Early spermatids: 1010.5;Late spermatids: 2756.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 5.7" "Lineage enriched" "Detected in many" 5 "B-cells: 5.7" "Group enriched" "Detected in some" 5 "HDLM-2: 13.9;RPTEC TERT1: 20.4;THP-1: 12.9;U-266/70: 11.3;U-937: 11.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (1.01e-1)" "unprognostic (7.29e-3)" "unprognostic (7.13e-2)" "unprognostic (2.05e-2)" "unprognostic (1.76e-2)" "unprognostic (4.92e-2)" "unprognostic (7.85e-2)" "unprognostic (7.78e-2)" "unprognostic (2.53e-3)" "unprognostic (4.06e-2)" "unprognostic (9.38e-2)" "unprognostic (8.38e-2)" "unprognostic (1.65e-2)" "unprognostic (2.80e-1)" "unprognostic (4.42e-2)" "unprognostic (1.88e-1)" "unprognostic (8.84e-2)" 0.3 0.0 0.1 3.0 0.1 0.4 0.6 0.0 0.7 0.3 0.1 1.1 1.1 0.2 0.2 0.3 0.4 0.6 0.4 0.1 0.0 0.3 1.7 6.1 7.7 0.4 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.3 1.3 0.0 0.3 0.3 0.7 0.0 1.5 0.1 0.1 1.5 0.7 65.4 0.3 1.1 0.1 3.2 3.8 1.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 12.9 0.0 0.5 0.0 0.0 0.0 11.3 0.0 0.4 0.2 11.1 0.0 0.0 0.6 0.0 0.0 0.5 0.0 5.7 0.0 0.0 1.2 1.9 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.1 0.0 0.7 0.1 0.0 0.4 0.1 0.2 0.1 0.3 0.6 0.2 0.0 0.0 0.7 7.5 0.1 1.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1010.5 0.0 0.0 1.3 0.0 2.7 0.3 0.0 0.1 0.4 0.5 0.2 1.3 0.0 0.4 0.3 6.8 0.0 1.0 0.0 2.0 10.1 1.0 2756.7 13.4 6.3 1.8 1.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 12.8 1.1 0.3 0.0 0.0 2.3 0.0 26.3 0.4 0.2 18.4 7.2 0.0 0.1 0.0 0.3 0.0 0.0 0.7 FCGR3A "CD16, CD16a, FCG3, FCGR3" ENSG00000203747 "Fc fragment of IgG receptor IIIa" P08637 1 161541759-161550737 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 206.3;lymphoid tissue: 306.8" "Cell type enhanced" "Detected in many" "dendritic cells: 333.4;Hofbauer cells: 193.1;Kupffer cells: 807.9;Macrophages: 300.0;NK-cells: 579.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "intermediate monocyte: 1763.5;neutrophil: 1169.8;non-classical monocyte: 3948.7" "Group enriched" "Detected in all" 5 "granulocytes: 1169.8;monocytes: 3948.7" "Not detected" "Not detected" "CAB032435, HPA055431" Supported "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB032435: AB_626925, HPA055431: AB_2682815" "unprognostic (5.27e-2)" "unprognostic (9.95e-2)" "unprognostic (2.37e-2)" "unprognostic (1.66e-1)" "unprognostic (1.39e-1)" "unprognostic (1.82e-1)" "unprognostic (2.24e-2)" "unprognostic (6.06e-2)" "unprognostic (2.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.98e-2)" "unprognostic (7.52e-2)" "prognostic unfavorable (3.22e-6)" "unprognostic (1.14e-1)" "unprognostic (4.66e-2)" "unprognostic (1.03e-2)" "unprognostic (7.51e-2)" 52.9 41.9 18.4 99.8 20.4 27.3 14.7 19.3 27.2 8.2 26.5 12.5 5.8 5.9 5.9 4.9 9.1 24.5 22.3 16.9 22.0 7.9 111.5 206.3 37.1 37.7 27.9 6.6 7.8 13.6 11.3 71.0 30.6 6.9 12.6 6.9 14.7 7.6 3.3 2.2 5.7 68.4 31.7 306.8 6.8 7.7 28.8 9.3 7.0 4.3 3.9 32.5 3.5 39.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.5 26.2 9.6 513.6 1763.5 4.9 3.7 4.7 205.9 175.8 1.4 3.0 184.0 1169.8 136.2 3948.7 4.6 2.6 734.1 18.4 20.4 19.3 27.2 16.9 22.0 37.7 27.9 30.6 31.7 28.8 39.8 2.7 22.4 24.6 0.7 6.5 0.5 0.1 0.0 0.0 0.2 1.4 3.4 0.7 8.6 10.5 3.7 2.1 1.2 333.4 0.0 0.0 0.2 1.4 0.1 0.0 18.9 0.0 16.4 0.0 0.0 1.4 3.9 0.0 0.1 18.9 0.1 8.6 5.3 193.1 0.0 0.1 0.1 0.0 807.9 7.4 3.7 0.3 300.0 0.0 20.6 77.2 0.1 579.9 0.0 0.1 0.0 0.0 0.0 22.1 0.0 0.0 0.8 5.8 1.5 19.7 1.1 0.4 0.0 0.5 0.2 0.0 2.1 88.0 0.0 0.0 0.3 GAA ENSG00000171298 "Glucosidase alpha, acid" P10253 17 80101556-80119881 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, FDA approved drug targets, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 156.2;Extravillous trophoblasts: 143.9;Kupffer cells: 122.7;Syncytiotrophoblasts: 166.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 66.6;eosinophil: 22.8;intermediate monocyte: 50.3;myeloid DC: 39.7;neutrophil: 27.0;non-classical monocyte: 68.5" "Group enriched" "Detected in all" 10 "dendritic cells: 39.7;granulocytes: 27.0;monocytes: 68.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026970, HPA029126" Enhanced Approved Vesicles NA NA 3800000 "Cluster 14: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA026970: AB_2672065, HPA029126: AB_2672918" "unprognostic (1.13e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (7.66e-4)" "unprognostic (2.94e-2)" "unprognostic (1.14e-2)" "unprognostic (7.96e-2)" "unprognostic (2.05e-2)" "unprognostic (1.19e-1)" "unprognostic (2.90e-1)" "unprognostic (1.43e-1)" "unprognostic (1.29e-2)" "unprognostic (2.76e-1)" "unprognostic (1.46e-1)" "unprognostic (7.02e-2)" "unprognostic (2.38e-1)" "unprognostic (1.78e-2)" "unprognostic (1.18e-1)" 31.7 29.9 16.9 22.6 20.8 16.7 30.1 19.2 26.5 25.8 17.1 29.2 24.7 31.2 35.2 15.8 29.1 29.9 35.1 18.3 24.7 37.6 47.3 44.4 22.5 28.2 21.6 18.8 37.2 33.3 38.8 48.5 26.6 33.2 8.7 6.6 37.7 23.6 47.0 25.5 26.9 14.6 21.0 54.3 26.9 56.0 26.0 20.4 32.6 25.1 7.0 31.5 22.0 31.4 35.6 67.8 13.2 43.2 40.4 40.2 85.1 21.8 39.6 16.2 13.2 20.3 56.3 12.7 56.5 17.3 13.8 14.8 4.1 25.2 3.8 16.5 49.9 0.2 12.8 73.3 69.7 1.7 40.4 86.7 35.4 30.6 10.5 32.8 28.9 33.5 12.9 51.5 12.4 81.3 6.0 8.4 27.3 8.7 46.8 30.9 44.8 22.2 13.1 36.5 15.1 43.4 28.5 31.3 39.0 8.1 89.5 50.1 18.8 59.7 31.5 43.6 8.1 121.4 36.5 3.8 19.1 32.8 38.4 0.6 66.6 22.8 3.7 50.3 4.4 3.1 2.8 3.8 39.7 3.0 3.2 2.3 27.0 3.0 68.5 9.5 2.1 32.9 16.9 20.8 19.2 26.5 18.3 24.7 28.2 21.6 26.6 21.0 26.0 31.4 21.9 19.2 41.3 31.6 9.3 11.2 19.6 38.7 8.0 16.1 24.1 28.2 19.9 24.3 24.7 14.7 8.4 156.2 11.8 11.5 5.9 25.2 55.7 14.3 16.7 21.6 6.1 4.8 16.2 15.8 143.9 33.0 20.4 27.8 8.8 28.5 23.6 26.4 99.8 11.8 18.9 10.9 12.2 122.7 29.6 29.3 23.9 83.9 24.9 20.6 39.1 32.1 8.2 11.6 12.5 9.4 13.5 19.2 12.9 20.2 31.4 21.5 9.3 18.5 6.6 15.0 13.9 66.0 29.4 10.3 8.4 166.2 8.2 30.2 14.4 14.8 GPNMB "HGFIN, NMB" ENSG00000136235 "Glycoprotein nmb" Q14956 7 23235967-23275108 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 581.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 327.1;Fibroblasts: 285.8;Hofbauer cells: 814.1;Macrophages: 328.9;Melanocytes: 597.7;Suprabasal keratinocytes: 359.7" "Cancer enhanced" "Detected in all" "melanoma: 354.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.1;intermediate monocyte: 3.9" "Lineage enriched" "Detected in single" 6 "monocytes: 3.9" "Cell line enriched" "Detected in many" 6 "ASC diff: 5015.0" "Region enhanced" "Detected in many" "olfactory bulb: 9.7" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 33000000 "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.37e-2)" "unprognostic (1.18e-1)" "unprognostic (6.65e-2)" "unprognostic (1.82e-1)" "unprognostic (5.14e-2)" "unprognostic (4.16e-1)" "unprognostic (1.39e-1)" "unprognostic (3.89e-2)" "unprognostic (7.13e-2)" "unprognostic (2.79e-1)" "unprognostic (2.83e-1)" "unprognostic (6.40e-2)" "unprognostic (2.08e-3)" "unprognostic (1.24e-2)" "unprognostic (3.46e-2)" "unprognostic (4.82e-1)" "unprognostic (6.95e-2)" 152.9 25.9 20.9 41.7 20.9 6.6 135.6 19.0 70.9 303.9 77.6 78.8 22.5 180.9 43.8 111.8 72.8 270.7 323.5 21.2 23.1 32.7 52.5 215.8 169.0 32.2 21.5 77.7 20.6 15.3 12.8 148.6 31.0 30.4 92.9 2.9 66.1 55.8 15.4 581.2 48.5 151.5 27.3 31.9 37.1 26.2 34.6 89.5 51.5 72.4 103.4 190.9 151.0 66.5 19.2 0.8 0.1 0.6 5015.0 908.0 0.4 33.6 564.1 27.9 116.2 0.2 0.8 0.7 1.4 109.5 49.1 118.3 0.7 0.7 14.2 1.3 1.3 0.1 0.9 2.5 61.5 1.5 0.6 630.3 134.8 46.3 4.7 734.9 0.3 1.4 0.3 0.6 150.2 3.5 0.7 0.7 0.6 0.5 0.5 0.4 1.4 7.6 71.2 443.4 2.4 0.6 0.1 175.6 841.5 1.3 2.3 2.8 0.1 163.0 17.8 297.8 5.5 5.1 8.6 1.2 56.3 2.6 166.1 0.6 2.1 0.1 0.0 3.9 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.5 0.1 0.1 0.4 0.0 0.5 20.9 20.9 19.0 70.9 21.2 23.1 32.2 21.5 31.0 27.3 34.6 66.5 18.0 19.2 24.3 0.3 3.2 327.1 7.1 58.5 150.2 0.4 6.6 24.5 204.2 2.8 16.0 75.4 0.0 7.2 2.2 0.1 3.9 0.6 3.0 2.5 44.0 15.0 0.0 0.0 0.5 0.8 4.6 285.8 12.2 2.5 22.7 0.1 4.6 5.1 814.1 1.7 1.2 0.0 12.2 188.4 100.7 5.5 129.8 328.9 597.7 12.2 3.2 0.2 1.0 55.8 0.1 0.6 0.0 108.0 10.2 1.9 0.0 1.2 3.4 0.6 0.0 20.6 53.4 3.9 1.4 65.3 359.7 28.9 5.7 0.1 0.0 11.9 GPR150 PGR11 ENSG00000178015 "G protein-coupled receptor 150" Q8NGU9 5 95620087-95622142 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.7;pancreas: 6.9" "Cell type enhanced" "Detected in some" "Early spermatids: 4.0;Extravillous trophoblasts: 5.3;granulocytes: 5.7;Hofbauer cells: 3.5;NK-cells: 2.1;Spermatocytes: 2.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.4;SiHa: 1.2;TIME: 2.7" "Low region specificity" "Detected in some" HPA026635 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 22: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA026635: AB_1849266" "unprognostic (3.03e-2)" "unprognostic (6.88e-3)" "unprognostic (1.01e-1)" "unprognostic (1.01e-2)" "unprognostic (5.95e-2)" "unprognostic (5.34e-4)" "unprognostic (1.98e-2)" "unprognostic (6.36e-2)" "unprognostic (3.13e-1)" "unprognostic (1.17e-2)" "unprognostic (1.94e-3)" "unprognostic (1.88e-2)" "unprognostic (1.76e-1)" "unprognostic (3.23e-2)" "unprognostic (4.42e-2)" "unprognostic (3.55e-2)" "unprognostic (1.26e-1)" 0.9 0.1 1.9 0.0 2.7 0.0 0.7 0.0 2.6 0.3 0.0 0.3 0.1 0.2 0.1 0.1 0.3 0.1 0.1 2.5 0.8 0.0 0.1 0.3 0.3 0.0 0.0 0.0 6.9 1.2 0.6 0.1 0.0 0.4 0.1 0.0 0.2 0.2 0.2 0.6 0.3 0.0 0.0 0.4 1.6 0.2 2.2 0.1 0.1 0.0 0.1 0.3 0.2 1.8 0.0 0.0 0.0 0.0 1.4 0.6 0.0 0.5 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.8 0.5 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.5 1.2 0.0 0.3 0.0 0.0 0.4 2.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.9 2.7 0.0 2.6 2.5 0.8 0.0 0.0 0.0 0.0 2.2 1.8 0.5 0.0 0.6 0.0 0.9 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 4.0 0.1 0.1 0.2 0.0 0.4 0.0 0.2 5.3 0.9 0.0 0.0 5.7 0.0 0.4 0.5 3.5 0.0 0.0 0.3 0.0 0.3 0.3 1.1 0.0 0.9 0.0 0.0 0.7 0.0 2.1 0.0 0.0 0.2 0.7 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 1.8 0.3 2.5 0.5 0.1 0.3 0.0 1.4 0.0 0.8 0.1 GPR34 ENSG00000171659 "G protein-coupled receptor 34" Q9UPC5 X 41688973-41697275 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 42.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 251.4;Kupffer cells: 173.3;Macrophages: 100.6;Microglial cells: 54.4" "Cancer enhanced" "Detected in all" "glioma: 26.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "basophil: 339.6;eosinophil: 117.9" "Lineage enriched" "Detected in many" 24 "granulocytes: 339.6" "Cell line enhanced" "Detected in single" "HMC-1: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010668, CAB025490" Uncertain Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB025490: , HPA010668: AB_1849294" "unprognostic (1.26e-2)" "unprognostic (1.08e-1)" "unprognostic (1.43e-2)" "unprognostic (1.44e-2)" "unprognostic (1.20e-1)" "unprognostic (3.74e-2)" "unprognostic (5.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.59e-2)" "unprognostic (9.81e-3)" "unprognostic (7.19e-2)" "unprognostic (1.74e-1)" "unprognostic (3.96e-1)" "unprognostic (2.72e-3)" "unprognostic (1.14e-1)" "unprognostic (1.88e-3)" "unprognostic (3.18e-2)" 28.2 17.1 5.2 15.1 5.2 0.9 21.5 6.1 5.8 14.0 5.6 12.0 6.5 6.7 2.7 8.2 7.8 17.0 8.3 5.0 7.6 5.0 8.5 10.9 20.0 10.6 7.9 7.3 5.4 5.3 1.4 42.7 11.4 3.2 13.1 0.6 3.6 8.8 0.8 1.0 14.6 16.3 9.9 15.6 7.8 2.7 9.7 6.9 3.7 4.6 16.7 13.3 1.7 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 339.6 9.7 117.9 0.0 12.9 0.4 1.5 0.4 0.1 2.0 1.2 0.1 0.3 1.1 14.3 7.0 0.3 0.6 2.8 5.2 5.2 6.1 5.8 5.0 7.6 10.6 7.9 11.4 9.9 9.7 18.8 0.9 0.0 2.8 1.0 2.0 0.6 0.2 0.0 0.0 0.0 0.5 2.3 1.2 0.0 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.0 0.6 0.1 0.1 5.0 1.2 0.4 0.7 0.0 1.6 1.0 0.5 0.0 37.3 0.0 2.9 0.8 251.4 0.0 0.9 0.0 0.0 173.3 13.6 1.9 0.9 100.6 1.8 54.4 7.1 0.1 1.0 3.5 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.1 0.0 0.8 19.7 0.6 0.3 0.0 0.2 0.4 1.0 2.5 7.2 0.1 0.1 0.0 GPX1 ENSG00000233276 "Glutathione peroxidase 1" P07203 3 49357176-49358353 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3273.8;Kupffer cells: 3971.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 1534.3;granulocytes: 1010.7;monocytes: 1337.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011582, HPA044758" Approved Supported Cytosol NA NA 3100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "CAB011582: AB_2112120, HPA044758: AB_2679076" "unprognostic (1.50e-2)" "unprognostic (4.34e-3)" "unprognostic (1.25e-1)" "prognostic favorable (7.78e-4)" "unprognostic (1.26e-1)" "unprognostic (1.83e-1)" "unprognostic (6.73e-3)" "unprognostic (5.03e-2)" "unprognostic (3.40e-2)" "unprognostic (2.48e-1)" "unprognostic (5.46e-2)" "unprognostic (1.53e-1)" "unprognostic (7.64e-3)" "unprognostic (9.14e-3)" "unprognostic (3.16e-2)" "unprognostic (5.72e-3)" "unprognostic (7.64e-3)" 321.4 200.0 178.3 151.9 186.6 246.7 151.5 190.2 298.9 90.9 247.3 86.9 122.2 82.2 17.8 134.3 86.5 91.1 95.5 173.1 198.9 152.9 281.6 168.3 174.3 234.0 213.0 61.9 74.4 35.2 85.7 121.2 208.3 107.0 42.7 8.3 113.1 53.9 157.1 70.4 113.6 70.4 218.0 195.9 92.9 31.5 217.6 75.3 82.1 61.7 86.6 116.8 94.9 256.3 322.8 189.2 72.6 95.4 113.5 205.9 225.9 217.7 114.7 151.5 80.1 157.8 229.7 0.6 301.6 139.8 181.7 93.2 98.8 660.3 31.6 200.2 271.6 224.8 190.2 397.4 575.6 161.0 594.4 455.9 267.6 292.4 221.5 190.0 341.5 78.6 0.5 179.3 125.9 0.8 51.2 407.0 441.3 147.4 510.5 190.8 93.8 120.3 258.2 385.6 87.7 178.5 249.5 1.5 287.3 75.7 1.5 559.5 546.5 209.7 236.0 385.8 453.6 1.1 127.9 116.3 390.5 436.3 507.8 1010.7 1337.0 707.6 69.8 483.7 100.9 314.2 127.7 83.7 1093.1 276.8 118.4 116.2 136.4 107.4 275.8 1534.3 233.3 1401.2 178.3 186.6 190.2 298.9 173.1 198.9 234.0 213.0 208.3 218.0 217.6 256.3 0.0 109.0 323.5 6.2 148.1 249.7 432.8 985.0 92.2 32.1 0.0 0.0 0.0 220.2 616.7 0.0 10.4 499.9 491.5 229.5 0.0 0.0 300.7 0.0 0.0 227.8 251.3 364.1 12.8 0.0 830.3 131.0 73.4 0.0 480.6 0.0 585.7 888.1 3273.8 1.7 17.9 285.0 386.6 3971.6 965.7 1102.9 134.5 1305.5 273.9 41.2 828.6 63.4 138.0 8.0 7.6 0.0 179.0 67.0 82.4 481.0 349.9 0.0 490.0 14.6 210.4 150.6 151.8 12.7 169.4 112.1 154.1 278.8 112.2 0.0 367.3 517.0 GRN "CLN11, PCDGF, PGRN" ENSG00000030582 "Granulin precursor" P28799 17 44345246-44353106 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 1420.7;Kupffer cells: 892.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 2057.5;intermediate monocyte: 1122.4;myeloid DC: 1534.2;neutrophil: 851.2;non-classical monocyte: 548.1;plasmacytoid DC: 1331.9" "Group enriched" "Detected in all" 9 "dendritic cells: 1534.2;granulocytes: 851.2;monocytes: 2057.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008763, CAB019394, HPA028747" Uncertain Enhanced Endosomes,Lysosomes "Secreted to blood" NA NA 138000000 110000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 18: U-2197 - ECM organization" "Cluster 4: Macrophages - Innate immune response" Lysosomes Endosomes "CAB019394: , HPA008763: AB_1850339, HPA028747: AB_10603767" "unprognostic (1.84e-1)" "unprognostic (2.34e-1)" "unprognostic (8.38e-3)" "unprognostic (2.82e-1)" "prognostic unfavorable (8.78e-4)" "unprognostic (7.41e-2)" "unprognostic (3.53e-3)" "unprognostic (3.57e-1)" "unprognostic (1.63e-1)" "unprognostic (2.40e-1)" "unprognostic (2.24e-2)" "unprognostic (1.52e-1)" "unprognostic (6.34e-2)" "unprognostic (2.54e-1)" "unprognostic (1.43e-1)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" 158.9 123.2 61.5 160.4 67.2 478.5 120.7 67.7 97.3 156.7 73.9 189.8 130.9 108.3 134.0 534.0 87.1 157.3 153.0 61.0 69.7 167.4 118.9 309.5 183.2 81.0 71.5 73.8 108.9 87.8 84.4 183.2 87.6 111.7 110.3 12.5 262.9 100.6 60.6 189.7 179.0 91.9 71.8 349.8 127.9 59.4 94.3 67.8 127.7 45.9 107.8 150.0 198.3 97.3 119.3 197.5 52.7 159.5 443.2 231.8 181.2 147.3 447.5 231.6 309.8 86.3 294.0 364.0 299.4 217.6 312.9 185.3 68.6 334.5 75.8 55.8 186.8 38.4 93.8 175.2 245.5 61.6 493.6 332.4 450.5 188.1 106.0 391.2 269.8 64.3 75.1 51.3 148.8 183.1 32.8 172.8 44.3 110.5 334.0 97.7 180.8 433.0 248.2 145.9 54.7 74.7 201.0 92.7 360.9 138.0 209.4 229.0 340.7 437.6 104.6 300.5 97.8 116.3 313.9 122.3 268.1 149.6 124.2 215.1 2057.5 176.5 35.1 1122.4 27.8 174.0 37.1 31.1 1534.2 112.2 27.8 26.5 851.2 30.6 548.1 1331.9 55.4 1613.4 61.5 67.2 67.7 97.3 61.0 69.7 81.0 71.5 87.6 71.8 94.3 97.3 113.0 86.6 83.3 12.7 82.8 112.7 151.1 574.2 97.9 23.6 85.7 69.7 90.7 133.0 332.7 218.8 18.8 429.1 195.7 494.8 9.8 447.7 2.1 103.8 83.8 170.9 124.3 38.7 6.8 307.3 324.1 149.4 83.6 372.5 75.5 90.0 207.8 84.7 1420.7 47.1 6.6 214.6 146.5 892.0 360.8 6.8 60.9 699.2 208.1 20.6 501.6 58.9 20.6 11.1 11.8 285.3 581.7 57.2 65.8 70.7 312.1 120.5 70.0 11.8 85.5 45.4 83.3 25.1 72.2 255.5 96.5 640.0 30.8 89.6 274.5 175.6 HEXB ENSG00000049860 "Hexosaminidase subunit beta" P07686 5 74640023-74722647 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 466.5;Hofbauer cells: 340.2;Syncytiotrophoblasts: 493.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 746.0;GAMG: 646.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055409, HPA056010" Enhanced "Intracellular and membrane" NA NA 40000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA055409: AB_2682808, HPA056010: AB_2683008" "unprognostic (3.45e-1)" "unprognostic (5.84e-2)" "unprognostic (1.85e-2)" "unprognostic (8.72e-2)" "unprognostic (1.12e-2)" "unprognostic (6.44e-3)" "prognostic unfavorable (3.36e-8)" "unprognostic (2.21e-1)" "unprognostic (5.01e-2)" "unprognostic (1.58e-3)" "unprognostic (6.45e-2)" "unprognostic (2.27e-1)" "unprognostic (1.07e-1)" "unprognostic (1.58e-1)" "unprognostic (1.31e-2)" "unprognostic (9.67e-2)" "unprognostic (1.64e-2)" 92.2 72.0 22.1 59.7 25.3 59.9 83.0 22.3 32.5 97.6 39.4 105.0 99.0 71.5 321.4 38.5 66.7 99.0 84.3 23.1 26.2 81.6 137.5 111.3 47.0 23.8 22.9 62.4 103.6 94.2 46.6 319.4 24.7 98.7 116.9 33.6 123.4 54.0 43.3 54.3 75.4 76.1 23.2 64.7 88.4 19.6 28.2 29.1 89.6 38.4 40.4 94.6 64.1 30.4 147.3 111.0 39.4 131.8 746.0 232.3 122.3 173.5 590.4 175.0 375.2 130.6 194.5 0.0 133.0 152.2 646.3 115.2 43.2 185.2 228.7 79.2 72.6 19.1 101.4 101.5 216.5 16.2 152.3 206.7 108.0 180.7 121.3 275.9 204.5 47.3 54.3 236.9 194.9 145.7 19.8 36.6 36.8 142.7 47.8 43.9 56.2 191.8 119.8 130.4 24.5 30.4 134.2 92.6 180.0 68.8 99.1 108.6 118.5 112.1 26.6 207.8 165.6 102.6 191.3 0.9 257.9 143.6 209.8 86.2 343.2 99.1 69.3 129.9 80.7 45.2 56.1 64.0 310.8 28.1 52.6 51.3 125.2 42.4 82.5 93.4 73.2 269.0 22.1 25.3 22.3 32.5 23.1 26.2 23.8 22.9 24.7 23.2 28.2 30.4 49.6 41.7 38.4 5.9 31.5 44.0 82.8 103.2 21.6 10.2 26.3 27.6 19.8 82.9 63.8 29.5 8.4 466.5 32.8 68.2 19.6 151.3 1.3 21.0 21.4 56.2 22.8 23.1 32.2 125.6 175.4 107.2 33.6 26.9 69.8 19.8 74.3 70.1 340.2 10.1 24.3 56.7 107.8 127.3 134.3 3.4 85.1 168.8 72.9 17.8 114.2 35.4 29.9 22.6 13.3 65.8 54.8 72.2 71.5 74.2 99.5 79.6 36.3 16.3 46.0 32.6 49.5 0.3 1.4 23.8 32.5 493.6 35.3 31.4 81.8 71.0 IFI30 "GILT, IFI-30, IP-30, IP30, MGC32056" ENSG00000216490 "IFI30 lysosomal thiol reductase" P13284 19 18173162-18178117 "Predicted intracellular proteins, Predicted membrane proteins" Immunity Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 572.7;lymphoid tissue: 708.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 155.9;Kupffer cells: 205.4;Langerhans cells: 139.3;Macrophages: 426.2;monocytes: 144.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 9509.8;eosinophil: 3890.4;intermediate monocyte: 14243.6;myeloid DC: 5699.9;non-classical monocyte: 9865.9" "Group enriched" "Detected in all" 8 "dendritic cells: 5699.9;granulocytes: 3890.4;monocytes: 14243.6" "Cell line enhanced" "Detected in many" "Daudi: 655.7;RPMI-8226: 717.7;SK-BR-3: 457.4;U-266/84: 794.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026650 Enhanced Supported Vesicles,Cytosol "Intracellular and membrane" NA NA 110000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Vesicles, Cytosol" "HPA026650: AB_10602237" "unprognostic (4.66e-2)" "unprognostic (1.25e-4)" "unprognostic (2.35e-3)" "unprognostic (7.40e-2)" "unprognostic (1.76e-2)" "unprognostic (3.11e-2)" "unprognostic (8.10e-3)" "unprognostic (2.40e-1)" "unprognostic (4.01e-2)" "unprognostic (9.19e-3)" "unprognostic (3.04e-1)" "unprognostic (1.19e-1)" "unprognostic (7.29e-11)" "unprognostic (3.50e-1)" "unprognostic (1.62e-2)" "unprognostic (3.39e-2)" "unprognostic (9.59e-3)" 132.4 121.0 18.4 708.3 20.8 283.8 58.6 20.3 104.5 40.8 48.7 129.0 197.3 22.2 26.9 38.7 57.3 109.6 31.2 18.0 23.3 80.3 148.2 572.7 370.7 32.0 24.9 14.8 61.3 75.0 27.9 128.8 40.5 31.6 148.0 2.6 66.3 22.0 12.6 55.0 153.6 165.0 26.8 385.3 112.2 16.0 69.4 91.9 54.2 9.0 221.0 215.7 19.6 49.8 115.5 59.2 0.4 37.9 11.2 19.9 102.6 11.8 17.2 34.6 91.8 132.3 193.1 655.7 96.6 39.7 175.2 85.1 69.9 30.1 3.7 182.5 55.2 8.1 98.1 188.9 111.8 20.1 46.9 70.4 60.4 59.8 19.7 4.4 2.0 23.8 96.8 394.8 16.6 217.3 9.9 2.5 21.2 380.6 68.7 65.8 4.5 717.7 101.1 3.7 5.3 8.0 200.5 457.4 11.3 7.4 31.6 8.8 4.2 55.2 34.2 120.7 12.0 14.6 794.7 368.5 154.1 133.5 8.5 106.9 9509.8 3890.4 40.8 14243.6 38.8 952.6 28.5 31.1 5699.9 708.1 19.7 24.3 2102.8 70.2 9865.9 173.2 41.5 11082.7 18.4 20.8 20.3 104.5 18.0 23.3 32.0 24.9 40.5 26.8 69.4 49.8 6.4 9.6 38.8 0.0 54.2 3.6 2.5 2.1 2.2 0.4 8.6 13.2 1.1 4.3 18.3 12.9 0.0 5.6 4.0 8.3 1.9 1.8 0.3 2.5 1.7 8.4 0.0 4.6 0.1 1.1 14.8 8.1 6.6 4.1 13.9 0.2 3.6 1.3 155.9 0.0 0.1 14.9 2.0 205.4 139.3 0.2 0.3 426.2 5.4 1.0 144.1 0.7 5.2 0.0 0.1 1.2 3.4 0.0 47.7 4.6 5.9 5.4 8.9 0.7 0.0 2.6 1.8 0.2 0.7 3.7 3.3 12.0 9.6 1.5 9.6 1.2 KCNAB2 "AKR6A5, HKvbeta2.1, HKvbeta2.2, KCNA2B" ENSG00000069424 "Potassium voltage-gated channel subfamily A regulatory beta subunit 2" Q13303 1 5990927-6101193 "Plasma proteins, Predicted intracellular proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 188.3" "Cell type enhanced" "Detected in many" "dendritic cells: 50.3;Excitatory neurons: 67.8;Hofbauer cells: 63.6;Inhibitory neurons: 49.2;Kupffer cells: 86.2;Macrophages: 51.3;Melanocytes: 64.0;NK-cells: 51.5" "Cancer enriched" "Detected in all" 7 "melanoma: 29.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 278.8;JURKAT: 142.7;U-937: 289.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB001975 Enhanced NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 10: Brain - Neuronal signaling" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB001975: " "unprognostic (6.60e-2)" "unprognostic (2.33e-2)" "unprognostic (3.97e-3)" "unprognostic (2.30e-2)" "unprognostic (1.76e-2)" "unprognostic (8.18e-3)" "unprognostic (4.30e-2)" "unprognostic (1.05e-1)" "unprognostic (4.85e-2)" "unprognostic (1.58e-2)" "unprognostic (7.71e-3)" "unprognostic (8.83e-3)" "prognostic unfavorable (3.50e-5)" "unprognostic (2.88e-2)" "unprognostic (3.10e-2)" "unprognostic (2.35e-1)" "unprognostic (5.24e-2)" 12.8 7.7 69.2 28.6 94.1 63.8 8.0 7.4 188.3 5.6 0.0 8.8 5.4 7.2 2.3 5.0 8.6 11.2 22.1 141.6 12.8 26.0 10.1 31.1 43.6 78.7 5.3 5.6 4.0 1.5 20.3 5.9 77.5 6.2 4.6 17.8 6.4 3.4 12.6 12.3 23.9 6.3 1.5 65.8 6.5 5.6 18.9 27.0 6.2 15.8 24.7 8.8 5.1 89.7 11.3 27.0 2.5 4.5 1.5 5.0 10.3 6.3 40.0 6.3 7.8 10.6 4.1 62.0 23.3 6.1 7.7 5.4 2.7 1.0 3.2 84.6 9.6 71.1 25.3 21.1 6.0 278.8 1.9 6.5 1.3 3.4 7.5 6.3 3.6 142.7 2.7 114.2 3.1 9.8 61.9 115.9 1.1 3.9 15.4 13.8 9.7 78.9 0.1 0.2 20.6 6.2 5.3 6.4 101.0 2.7 5.4 117.3 1.1 1.3 9.4 14.4 7.5 84.4 122.4 100.4 12.7 289.2 1.9 4.4 34.3 18.6 29.8 27.2 26.8 7.5 18.2 28.0 31.0 8.7 18.7 20.6 14.4 19.4 25.0 12.7 19.1 43.2 69.2 94.1 7.4 188.3 141.6 12.8 78.7 5.3 77.5 1.5 18.9 89.7 3.0 0.0 6.6 7.5 23.0 4.8 1.7 1.8 1.8 24.0 1.2 2.3 15.7 7.2 1.5 1.8 6.2 0.5 50.3 0.3 0.0 0.3 5.8 3.4 1.9 3.1 0.0 11.1 67.8 1.4 2.3 3.5 2.0 0.6 8.8 2.9 3.9 1.0 63.6 6.7 49.2 0.5 2.0 86.2 19.0 5.2 3.7 51.3 64.0 5.6 26.6 4.9 51.5 8.5 6.1 0.6 0.1 2.6 23.4 0.4 0.1 40.8 8.7 11.8 0.0 2.1 3.1 3.2 2.9 0.7 2.8 0.8 44.3 2.5 0.3 0.6 LAIR1 CD305 ENSG00000167613 "Leukocyte associated immunoglobulin like receptor 1" Q6GTX8 19 54351384-54370558 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 28.1;lymphoid tissue: 46.3" "Cell type enhanced" "Detected in many" "dendritic cells: 106.6;granulocytes: 109.3;Hofbauer cells: 190.9;Kupffer cells: 100.9;Macrophages: 128.9;NK-cells: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "HMC-1: 7.5;Karpas-707: 19.4;THP-1: 22.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011155 Enhanced Supported "Plasma membrane" NA NA 350000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "HPA011155: AB_1852685" "unprognostic (1.91e-1)" "unprognostic (1.12e-2)" "unprognostic (2.81e-2)" "unprognostic (1.25e-2)" "unprognostic (2.03e-2)" "unprognostic (4.38e-2)" "unprognostic (2.16e-2)" "unprognostic (1.74e-1)" "unprognostic (5.00e-2)" "unprognostic (2.24e-1)" "unprognostic (2.21e-1)" "unprognostic (7.11e-2)" "prognostic unfavorable (5.01e-5)" "unprognostic (1.72e-1)" "unprognostic (2.72e-3)" "unprognostic (3.52e-2)" "unprognostic (5.22e-2)" 23.3 11.6 0.5 3.0 0.3 4.4 12.3 1.6 1.3 4.1 0.5 6.9 0.4 3.8 0.2 2.6 5.5 0.9 3.8 0.4 0.6 4.6 3.5 28.1 5.8 1.0 0.8 2.2 3.8 0.1 4.4 1.0 1.0 5.4 0.2 0.1 5.8 0.2 1.3 2.1 14.3 2.0 0.4 46.3 5.0 1.7 1.1 3.9 3.3 0.1 0.9 6.3 3.0 0.9 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 3.3 7.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 19.4 0.0 0.0 2.6 1.8 0.0 0.0 0.0 2.6 0.2 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 22.9 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 3.2 0.3 13.1 4.2 11.7 7.7 9.8 4.8 2.1 2.3 4.1 0.1 5.8 3.4 4.4 0.7 6.3 11.0 11.2 1.7 3.8 0.5 0.3 1.6 1.3 0.4 0.6 1.0 0.8 1.0 0.4 1.1 0.9 1.9 16.0 25.6 0.3 26.1 0.6 0.6 0.2 0.0 5.6 1.1 2.9 1.5 1.5 11.2 0.0 37.5 5.3 106.6 0.2 0.0 0.1 32.2 0.6 0.7 5.0 0.0 10.9 0.4 0.0 5.2 2.5 0.0 0.7 109.3 0.6 3.6 1.2 190.9 1.7 0.5 0.0 0.0 100.9 17.7 26.1 0.3 128.9 0.0 13.1 22.5 0.9 98.9 0.0 0.6 0.1 0.0 0.0 5.1 0.7 0.3 0.3 11.0 15.4 0.0 0.9 1.3 2.9 1.0 0.4 1.1 10.0 32.1 0.2 0.2 0.9 LIPA "CESD, LAL" ENSG00000107798 "Lipase A, lysosomal acid type" P38571 10 89213569-89414557 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 398.4" "Cell type enhanced" "Detected in many" "Hofbauer cells: 515.0;Kupffer cells: 714.8;Macrophages: 303.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 167.3;intermediate monocyte: 355.1;myeloid DC: 123.6;non-classical monocyte: 198.5" "Group enriched" "Detected in all" 6 "dendritic cells: 123.6;monocytes: 355.1" "Cell line enhanced" "Detected in many" "A-431: 354.4;AN3-CA: 367.8;ASC TERT1: 450.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034892, HPA057052" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" "Intracellular and membrane" NA NA 280000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Cytosol" "Nucleoplasm, Nucleoli fibrillar center" "CAB034892: AB_784329, HPA057052: AB_2683322" "unprognostic (1.27e-1)" "unprognostic (3.23e-1)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" "unprognostic (7.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (4.28e-2)" "unprognostic (1.08e-1)" "unprognostic (7.30e-3)" "unprognostic (1.39e-2)" "unprognostic (1.40e-1)" "unprognostic (4.42e-2)" "unprognostic (3.42e-2)" "unprognostic (5.71e-2)" 76.0 46.3 43.5 66.7 65.2 39.8 47.8 64.1 74.4 54.0 39.0 67.7 167.6 38.8 21.7 28.6 37.8 83.5 24.2 43.5 53.1 44.9 218.9 169.5 159.3 74.7 55.5 32.7 21.4 68.9 12.7 79.1 82.2 30.7 72.0 12.6 22.5 33.8 11.8 18.7 227.5 47.7 65.4 398.4 34.3 13.4 57.0 44.5 31.6 22.5 45.5 58.4 19.3 115.5 354.4 49.4 30.7 367.8 343.5 450.8 10.0 171.4 194.8 65.5 121.5 18.6 176.6 63.9 34.0 264.4 73.7 338.7 13.8 92.8 53.6 86.1 34.7 25.1 19.1 81.5 87.6 48.8 48.9 190.4 69.2 72.9 40.6 88.2 14.9 45.4 0.3 108.5 58.3 28.2 45.7 34.6 22.7 62.4 60.0 26.4 39.0 60.5 69.2 50.9 10.5 21.8 41.4 49.9 133.9 20.4 64.4 65.8 26.2 58.8 15.5 132.1 44.6 60.0 65.7 25.8 71.4 112.9 82.1 4.2 167.3 16.9 40.0 355.1 40.6 31.9 35.8 38.8 123.6 33.4 36.7 40.4 7.1 29.8 198.5 25.0 38.2 159.6 43.5 65.2 64.1 74.4 43.5 53.1 74.7 55.5 82.2 65.4 57.0 115.5 75.5 41.7 33.8 11.1 35.9 17.7 30.3 58.1 25.6 5.4 16.1 14.1 9.6 45.8 31.9 33.1 0.0 34.8 31.4 2.8 21.5 35.1 6.8 11.4 20.4 56.7 21.8 27.4 34.4 36.2 32.9 34.6 21.4 15.5 28.5 10.8 54.7 66.7 515.0 16.8 15.1 8.9 40.7 714.8 69.0 2.7 11.5 303.1 48.0 30.0 71.7 33.1 29.9 15.1 143.0 19.3 12.0 21.8 15.4 11.3 161.0 14.0 28.8 2.2 6.6 19.7 21.0 5.1 13.8 31.9 12.5 20.0 33.1 17.6 9.1 24.0 LRPAP1 "A2MRAP, HBP44, RAP" ENSG00000163956 "LDL receptor related protein associated protein 1" P30533 4 3503612-3532446 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Heparin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 584.3;Syncytiotrophoblasts: 693.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008001, CAB025518" Enhanced Supported Supported "Endoplasmic reticulum" NA NA 810000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "CAB025518: , HPA008001: AB_1853292" "unprognostic (3.20e-3)" "unprognostic (7.01e-2)" "unprognostic (2.30e-1)" "unprognostic (2.22e-2)" "unprognostic (1.37e-2)" "unprognostic (9.61e-2)" "unprognostic (1.01e-2)" "unprognostic (3.89e-3)" "unprognostic (8.58e-2)" "unprognostic (6.12e-2)" "unprognostic (2.14e-3)" "unprognostic (2.19e-1)" "prognostic favorable (4.67e-11)" "unprognostic (6.25e-2)" "unprognostic (1.56e-1)" "unprognostic (2.58e-1)" "unprognostic (5.61e-2)" 6.6 9.0 6.6 2.6 10.3 6.0 6.4 8.6 7.6 8.9 10.7 7.6 3.3 8.6 3.2 5.8 7.5 1.9 19.3 5.8 8.1 12.7 9.6 8.5 2.1 8.0 6.9 9.5 14.4 7.7 14.4 6.3 7.9 8.2 1.7 2.8 10.1 4.1 8.9 6.3 6.7 1.9 5.2 8.6 9.2 9.2 7.5 1.6 8.9 2.4 1.4 7.3 6.3 6.3 3.7 7.4 5.7 8.2 5.5 2.9 12.5 5.9 4.8 4.3 3.1 14.9 7.0 2.1 6.0 4.2 7.0 6.2 3.4 5.8 2.4 1.6 7.9 2.9 7.8 10.4 4.2 4.7 12.5 4.0 4.3 3.9 1.9 4.7 5.2 3.9 5.1 7.0 3.6 5.9 3.1 18.4 4.9 5.1 7.8 4.3 4.2 7.1 4.8 8.6 5.6 4.6 7.4 3.0 8.1 3.4 6.7 8.6 5.6 5.1 4.7 4.1 8.2 4.2 2.9 2.8 5.9 13.3 7.2 21.9 23.2 60.1 9.3 19.7 8.1 9.9 8.6 8.8 13.3 10.0 9.4 8.6 20.5 11.7 19.1 10.2 11.5 27.3 6.6 10.3 8.6 7.6 5.8 8.1 8.0 6.9 7.9 5.2 7.5 6.3 95.0 109.0 90.9 21.2 78.0 67.8 174.6 267.7 52.9 70.6 75.3 84.2 165.9 108.7 158.7 195.0 45.9 584.3 75.8 147.7 50.9 159.3 40.4 85.5 229.6 88.2 82.6 35.7 22.5 107.9 184.0 152.5 79.0 71.2 81.1 102.3 62.4 92.6 243.1 38.7 20.6 121.6 164.8 100.5 80.2 60.0 126.2 154.2 147.7 16.9 107.1 140.0 91.6 28.1 16.7 95.4 153.4 151.6 205.2 124.5 204.6 273.7 144.8 86.2 78.9 82.8 108.1 272.5 161.4 40.7 61.4 693.5 86.0 99.9 109.9 140.5 LY86 "dJ80N2.1, MD-1" ENSG00000112799 "Lymphocyte antigen 86" O95711 6 6588108-6654983 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 78.4" "Group enriched" "Detected in many" 9 "B-cells: 124.9;Hofbauer cells: 191.7;Kupffer cells: 199.1;Langerhans cells: 118.6;Macrophages: 149.8;Microglial cells: 105.9;monocytes: 155.6" "Cancer enhanced" "Detected in all" "glioma: 22.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 426.6;myeloid DC: 426.1" "Group enriched" "Detected in all" 43 "B-cells: 335.1;dendritic cells: 426.1;monocytes: 426.6" "Cell line enhanced" "Detected in some" "Daudi: 69.5;NB-4: 44.7;RPMI-8226: 245.0;THP-1: 103.8;U-937: 45.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025000, HPA044895" Approved "Secreted to blood" NA NA 77000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" "CAB025000: , HPA044895: AB_2679138" "unprognostic (1.82e-1)" "unprognostic (2.49e-3)" "unprognostic (2.01e-2)" "unprognostic (7.88e-2)" "unprognostic (2.15e-1)" "unprognostic (1.93e-1)" "unprognostic (2.53e-1)" "unprognostic (1.46e-3)" "unprognostic (3.52e-2)" "unprognostic (3.17e-1)" "unprognostic (1.69e-1)" "unprognostic (1.16e-1)" "unprognostic (5.82e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (5.61e-4)" "unprognostic (1.11e-1)" "unprognostic (4.20e-2)" 9.7 10.3 14.0 30.9 13.5 29.2 7.4 14.7 22.0 8.2 14.2 7.6 4.9 3.8 2.8 3.1 4.3 14.6 2.9 13.5 15.8 3.1 13.3 29.7 72.1 17.8 15.4 3.3 3.0 3.4 2.3 14.5 18.7 3.8 11.1 1.2 5.5 6.2 0.7 3.4 16.8 11.1 17.8 52.7 6.2 1.8 18.0 15.1 1.5 1.1 78.4 15.6 1.1 24.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 44.7 0.0 0.0 0.0 8.0 0.0 245.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 103.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 30.3 0.0 45.8 0.0 4.1 426.6 3.5 1.0 234.9 0.7 335.1 1.1 1.1 426.1 248.8 4.7 2.7 9.1 5.3 88.3 16.3 1.8 221.1 14.0 13.5 14.7 22.0 13.5 15.8 17.8 15.4 18.7 17.8 18.0 24.8 1.2 0.0 15.0 1.6 124.9 2.0 0.0 0.0 0.0 0.0 0.9 3.7 1.5 1.5 1.3 0.0 0.0 1.4 9.8 0.0 0.0 0.0 3.4 0.4 0.1 5.4 0.0 3.8 3.8 0.0 1.8 2.1 0.0 0.0 1.3 0.0 4.2 1.3 191.7 0.0 0.6 0.3 0.0 199.1 118.6 15.4 0.3 149.8 0.0 105.9 155.6 0.0 4.1 0.5 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.7 0.4 6.6 0.4 0.2 5.3 0.2 0.3 2.4 1.9 3.6 0.0 0.2 0.2 MAFB KRML ENSG00000204103 "MAF bZIP transcription factor B" Q9Y5Q3 20 40685848-40689236 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 273.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 264.0;Hofbauer cells: 377.6;Kupffer cells: 672.8;Macrophages: 456.7;Squamous epithelial cells: 361.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 88.3;non-classical monocyte: 121.4" "Lineage enriched" "Detected in many" 15 "monocytes: 121.4" "Cell line enhanced" "Detected in some" "HSkMC: 28.6;hTCEpi: 61.2;SCLC-21H: 16.7;SiHa: 15.6;U-138 MG: 16.4;U-2197: 24.4;U-87 MG: 16.0" "Low region specificity" "Detected in many" HPA005653 Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" Yes NA "Cluster 51: Monocytes - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "Nucleoli, Golgi apparatus, Cytosol" "HPA005653: AB_1079293" "unprognostic (1.55e-1)" "unprognostic (1.17e-2)" "unprognostic (1.16e-3)" "prognostic unfavorable (5.64e-4)" "unprognostic (9.16e-2)" "unprognostic (3.92e-2)" "unprognostic (1.10e-1)" "unprognostic (2.10e-1)" "unprognostic (2.57e-2)" "unprognostic (6.09e-2)" "unprognostic (5.45e-3)" "unprognostic (9.92e-2)" "unprognostic (3.95e-2)" "unprognostic (1.05e-1)" "unprognostic (3.21e-3)" "unprognostic (3.49e-2)" "unprognostic (2.30e-2)" 35.3 13.8 4.8 37.3 4.9 59.2 27.3 4.4 10.5 16.5 6.9 9.5 7.8 9.3 5.4 33.0 11.3 24.4 10.7 3.7 5.7 17.5 29.3 20.9 27.8 14.3 6.3 6.8 15.8 273.1 3.1 13.2 7.2 8.3 7.2 0.6 18.3 4.7 15.8 85.3 13.2 14.2 9.0 96.3 11.0 3.9 13.1 6.7 50.1 16.7 12.7 13.9 21.9 15.8 0.0 0.0 0.0 2.6 1.5 0.2 0.4 0.3 0.1 0.3 0.1 0.4 0.2 0.0 1.9 0.4 0.0 3.8 0.0 0.0 0.0 0.0 1.4 0.0 1.2 0.2 0.9 0.0 0.1 28.6 61.2 0.2 2.1 0.0 0.4 0.0 0.0 0.0 0.1 0.9 0.3 7.4 2.6 6.2 0.0 0.0 0.0 0.0 0.5 0.4 16.7 1.4 15.6 1.5 3.9 5.4 1.5 0.3 0.5 16.4 0.3 24.4 0.0 0.0 0.0 0.0 16.0 0.6 0.0 0.4 24.3 0.0 0.0 88.3 0.0 0.0 0.0 0.1 7.9 0.1 0.0 0.0 2.1 0.0 121.4 0.1 0.0 10.6 4.8 4.9 4.4 10.5 3.7 5.7 14.3 6.3 7.2 9.0 13.1 15.8 70.0 22.4 37.9 1.6 7.8 68.6 50.5 17.1 264.0 12.0 112.2 217.8 208.9 7.2 16.8 51.5 25.0 9.8 7.6 117.1 1.9 2.3 0.8 15.7 64.4 39.1 57.7 4.0 0.8 3.4 2.8 172.7 49.5 27.6 10.8 0.9 34.6 36.1 377.6 3.3 25.4 50.7 6.1 672.8 91.7 2.8 29.5 456.7 21.4 6.5 65.3 21.9 3.1 2.0 1.3 4.9 30.9 24.5 5.6 29.7 89.5 1.3 2.4 8.3 13.1 160.6 102.4 0.8 1.7 361.5 88.2 12.4 9.5 114.6 39.0 19.2 MAN2B1 "LAMAN, MANB" ENSG00000104774 "Mannosidase alpha class 2B member 1" O00754 19 12646511-12666742 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 32.8;Plasma cells: 78.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 201.8;intermediate monocyte: 178.8;myeloid DC: 158.8;non-classical monocyte: 138.4;plasmacytoid DC: 187.5" "Group enriched" "Detected in all" 5 "dendritic cells: 187.5;monocytes: 201.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041530, HPA053404" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 3200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Vesicles" "HPA041530: AB_10795639, HPA053404: " "unprognostic (6.63e-2)" "unprognostic (3.61e-1)" "unprognostic (2.20e-2)" "unprognostic (5.48e-2)" "unprognostic (3.81e-1)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (1.84e-2)" "unprognostic (9.55e-2)" "unprognostic (1.95e-1)" "unprognostic (2.79e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.94e-5)" "unprognostic (4.00e-1)" "unprognostic (4.17e-2)" "unprognostic (2.22e-1)" "unprognostic (1.51e-1)" 35.8 21.4 5.3 54.6 6.4 83.6 24.8 6.6 5.9 19.6 18.5 30.3 31.0 21.8 9.0 19.8 19.9 28.4 16.0 4.9 7.4 17.3 23.7 46.8 52.1 10.3 6.7 16.7 39.7 16.6 9.9 24.6 9.5 20.5 22.6 1.6 35.2 14.9 12.1 28.9 33.6 20.2 8.9 70.1 32.7 6.4 9.7 23.1 16.3 9.4 39.3 35.6 16.7 12.4 52.4 26.3 26.4 31.3 85.8 57.3 74.0 37.9 79.2 33.1 32.4 21.3 21.4 56.9 44.9 30.4 9.4 40.1 13.6 25.6 15.7 28.5 41.6 19.8 13.6 34.9 43.5 131.6 130.2 68.5 49.2 18.5 23.3 35.6 31.7 21.1 25.6 41.9 17.8 40.9 17.9 74.2 21.9 26.2 32.8 40.8 36.1 28.8 38.9 59.8 8.2 25.5 37.7 32.0 63.0 15.8 49.4 80.0 42.0 44.8 18.4 44.0 36.2 55.4 65.5 28.0 30.4 127.5 51.2 12.2 201.8 29.7 31.9 178.8 35.4 32.9 28.9 29.0 158.8 26.4 15.4 15.9 29.4 13.2 138.4 187.5 30.7 150.3 5.3 6.4 6.6 5.9 4.9 7.4 10.3 6.7 9.5 8.9 9.7 12.4 1.6 6.4 7.5 8.5 25.1 3.6 2.0 2.7 14.2 2.6 1.9 1.0 0.9 2.8 2.0 1.8 0.0 2.5 20.5 2.0 1.9 1.7 3.7 1.4 2.5 3.1 1.8 9.4 7.8 2.3 2.8 7.2 20.9 1.3 1.3 3.4 1.8 0.8 8.4 0.0 6.4 0.9 0.0 15.4 24.7 11.1 3.7 32.8 1.8 17.8 11.0 1.5 9.2 3.5 13.4 1.5 2.5 4.5 78.1 2.5 3.8 1.5 3.9 4.0 13.1 2.3 2.0 0.6 1.6 11.5 3.3 2.7 9.4 2.7 2.0 2.0 MFSD1 "FLJ14153, Minerva, UG0581B09" ENSG00000118855 "Major facilitator superfamily domain containing 1" Q9H3U5 3 158732198-158829719 "Predicted intracellular proteins, Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 214.4;Kupffer cells: 289.7;Macrophages: 212.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 254.5;granulocytes: 246.0;monocytes: 288.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065858 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" Cytosol "HPA065858: AB_2685569" "unprognostic (9.94e-2)" "unprognostic (3.12e-3)" "unprognostic (3.54e-2)" "unprognostic (1.00e-1)" "unprognostic (2.16e-2)" "unprognostic (7.37e-2)" "unprognostic (1.28e-2)" "unprognostic (2.61e-2)" "unprognostic (2.52e-1)" "unprognostic (1.15e-1)" "unprognostic (6.48e-2)" "unprognostic (2.92e-1)" "prognostic favorable (5.60e-5)" "unprognostic (1.62e-1)" "unprognostic (6.33e-3)" "unprognostic (4.66e-2)" "unprognostic (2.57e-1)" 39.7 27.4 11.0 38.1 12.9 35.9 26.9 20.2 15.8 22.5 23.8 31.1 25.7 16.1 19.4 35.0 21.4 32.3 17.2 15.7 14.5 30.3 39.5 40.5 34.5 15.8 12.2 17.9 31.5 36.0 7.5 30.7 16.4 26.8 22.2 8.4 48.4 23.4 11.1 23.4 23.2 26.2 11.5 42.0 36.1 18.0 16.1 16.1 27.9 16.9 21.5 40.0 19.6 17.3 83.3 28.9 9.1 26.3 51.0 45.0 35.9 109.7 61.8 46.5 45.9 10.3 82.8 19.7 73.5 81.9 24.1 37.0 22.0 26.7 40.9 68.2 33.7 57.2 24.0 6.7 52.1 206.0 135.7 59.3 38.5 39.7 9.5 15.9 38.0 14.0 39.9 32.9 85.1 19.2 11.3 83.2 8.5 29.9 50.9 19.8 11.3 170.9 18.1 16.3 18.2 29.8 76.7 70.0 25.0 8.3 56.9 100.1 102.8 58.6 23.2 87.3 60.5 98.3 94.4 9.6 74.1 162.0 39.7 102.4 288.8 246.0 36.6 223.4 35.3 54.2 30.3 33.9 254.5 44.5 32.2 35.5 97.1 32.9 187.8 81.8 38.9 252.1 11.0 12.9 20.2 15.8 15.7 14.5 15.8 12.2 16.4 11.5 16.1 17.3 28.5 19.2 34.0 12.1 39.6 21.4 46.2 38.4 33.0 11.8 33.3 19.7 22.2 20.0 51.6 22.0 6.2 27.5 24.1 33.3 19.6 34.0 5.3 13.6 22.7 28.2 22.8 56.0 14.6 28.5 33.6 33.7 23.9 17.2 48.8 8.9 37.1 34.4 214.4 18.5 15.2 28.6 34.6 289.7 90.7 6.7 12.2 212.3 32.0 16.9 88.7 26.0 25.7 15.1 29.4 29.0 29.9 11.3 32.9 30.0 27.1 31.8 59.3 10.5 13.1 11.8 23.8 11.6 8.7 61.2 26.0 56.0 22.3 19.4 28.3 58.4 MS4A7 "CD20L4, CFFM4, MS4A8" ENSG00000166927 "Membrane spanning 4-domains A7" Q9GZW8 11 60378485-60395951 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 196.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 311.4;Kupffer cells: 1060.3;Macrophages: 567.5;monocytes: 184.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "intermediate monocyte: 747.4;non-classical monocyte: 1486.0" "Lineage enriched" "Detected in many" 12 "monocytes: 1486.0" "Cell line enriched" "Detected in some" 25 "THP-1: 114.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA017418, CAB026387" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB026387: , HPA017418: AB_1854137" "unprognostic (1.43e-1)" "unprognostic (2.60e-3)" "unprognostic (3.24e-2)" "unprognostic (9.67e-2)" "unprognostic (2.04e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-1)" "unprognostic (9.51e-2)" "unprognostic (3.02e-2)" "unprognostic (4.85e-2)" "unprognostic (5.79e-2)" "unprognostic (1.90e-1)" "unprognostic (1.43e-2)" "unprognostic (4.59e-2)" "unprognostic (3.90e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" 46.9 37.6 6.3 50.9 5.0 10.7 30.7 4.5 13.7 18.2 13.9 21.4 17.6 7.6 4.1 12.7 6.6 46.8 9.9 4.2 8.7 8.0 66.5 75.7 23.2 12.8 10.4 6.0 6.0 9.0 4.7 43.9 11.4 4.9 23.3 1.2 6.7 9.0 1.9 2.3 25.1 15.9 7.4 196.6 14.8 4.7 17.1 18.2 7.3 4.1 18.6 41.2 3.9 18.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 2.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.5 0.1 0.0 0.1 1.1 0.1 0.1 0.0 2.8 0.0 0.1 0.1 0.8 0.5 0.0 0.0 114.2 0.0 0.1 0.1 0.1 0.1 0.2 0.2 3.0 0.0 3.1 0.0 8.3 188.0 2.5 0.8 747.4 1.1 22.3 0.6 0.5 120.9 19.7 0.8 0.4 9.3 0.8 1486.0 3.2 0.9 137.8 6.3 5.0 4.5 13.7 4.2 8.7 12.8 10.4 11.4 7.4 17.1 18.3 5.0 12.8 31.4 0.0 30.6 2.7 0.8 0.0 0.6 3.6 14.7 9.9 2.1 0.0 3.7 9.2 0.0 1.0 1.4 0.3 0.0 0.0 2.4 0.1 0.0 12.2 0.0 10.1 0.1 0.2 1.7 3.9 1.5 0.1 13.9 0.1 11.0 4.7 311.4 0.0 0.2 0.0 0.0 1060.3 93.4 1.2 1.2 567.5 1.8 59.0 184.8 0.4 4.1 0.0 0.3 0.1 1.1 0.0 1.8 1.1 0.0 0.7 7.3 0.5 19.7 2.2 1.2 0.0 0.4 0.9 1.8 1.9 5.3 0.3 0.1 1.0 PSAP "GLBA, SAP1, SAP2" ENSG00000197746 Prosaposin P07602 10 71816298-71851325 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Lipid metabolism, Sphingolipid metabolism" "Disease variant, Gangliosidosis, Gaucher disease, Leukodystrophy, Metachromatic leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2792.8;Kupffer cells: 2427.0;Macrophages: 1916.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 11615.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 5104.0;hTERT-RPE1: 6978.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004426, CAB004647" Supported Supported Vesicles "Intracellular and membrane" NA NA 88000000 "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Vesicles "CAB004647: AB_425625, HPA004426: AB_1079701" "unprognostic (4.43e-3)" "unprognostic (2.69e-1)" "unprognostic (1.64e-2)" "unprognostic (8.00e-2)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" "unprognostic (8.36e-3)" "unprognostic (2.79e-1)" "unprognostic (3.31e-2)" "unprognostic (3.25e-2)" "unprognostic (2.30e-3)" "unprognostic (2.00e-2)" "unprognostic (3.62e-3)" "unprognostic (6.47e-2)" "unprognostic (4.42e-2)" "unprognostic (2.34e-1)" "unprognostic (2.06e-1)" 1068.6 1192.2 831.4 874.2 946.7 834.2 683.8 873.7 831.7 1073.9 1023.0 667.1 475.6 879.3 951.2 605.5 724.7 1115.6 1413.3 830.5 1081.8 860.4 906.4 1118.6 956.1 957.6 894.0 1106.9 544.7 1167.5 563.5 869.3 885.3 773.9 625.5 665.2 580.9 936.8 1409.5 544.4 487.7 1138.6 1025.9 1045.9 664.0 489.1 1048.8 672.3 875.9 987.5 560.4 941.2 578.3 1325.1 455.9 847.4 540.4 1121.0 5104.0 2910.1 1900.2 799.9 2368.3 620.8 735.9 795.4 1131.9 245.6 1608.1 1321.6 1038.9 964.1 207.5 659.1 434.8 481.4 381.8 288.9 352.3 459.6 1970.7 188.8 1596.0 1871.8 1479.1 625.7 1177.6 6978.9 1128.1 345.8 420.5 1158.1 777.0 294.9 843.8 290.1 249.5 575.4 404.0 172.9 301.3 696.7 730.3 764.4 584.4 515.8 751.1 2248.3 3122.2 700.4 454.4 431.1 1467.0 861.8 610.0 587.1 670.5 1289.0 1038.7 435.4 1375.5 374.4 650.0 863.2 10095.9 1127.5 424.2 11615.6 349.8 466.7 342.9 368.8 3481.1 425.5 370.1 350.6 2890.4 365.8 10148.2 1758.2 422.8 15009.0 831.4 946.7 873.7 831.7 830.5 1081.8 957.6 894.0 885.3 1025.9 1048.8 1325.1 263.2 253.2 339.0 136.8 173.9 228.3 253.4 487.0 108.1 193.8 254.6 158.7 664.1 253.1 318.9 476.3 127.2 891.6 260.2 434.8 70.5 1043.6 19.3 147.0 246.6 311.4 261.9 160.5 86.1 456.1 872.6 623.8 187.6 195.2 398.1 210.8 426.9 509.2 2792.8 333.1 93.7 242.2 343.8 2427.0 779.7 54.1 458.6 1916.9 663.5 105.9 1528.9 495.6 182.3 92.5 117.6 357.7 298.3 551.8 503.0 244.8 370.6 311.6 297.2 164.3 276.1 273.6 263.8 55.2 126.3 137.2 198.0 1073.2 138.9 624.1 228.3 223.9 RENBP "RBP, RNBP" ENSG00000102032 "Renin binding protein" P51606 X 153935269-153944687 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 43.0;lymphoid tissue: 67.0" "Cell type enhanced" "Detected in many" "granulocytes: 127.7;Hofbauer cells: 183.4;Kupffer cells: 70.7;Proximal tubular cells: 204.2" "Cancer enhanced" "Detected in all" "melanoma: 57.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 4 "granulocytes: 2.7;monocytes: 1.6" "Cell line enhanced" "Detected in many" "EFO-21: 35.5;HMC-1: 121.4;SK-MEL-30: 86.4;U-266/84: 74.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000428, HPA000522" Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA000428: AB_1079799, HPA000522: AB_1079798" "unprognostic (3.08e-1)" "prognostic favorable (3.95e-4)" "unprognostic (1.12e-2)" "unprognostic (3.29e-1)" "unprognostic (8.83e-3)" "unprognostic (1.85e-1)" "unprognostic (5.22e-2)" "unprognostic (1.02e-2)" "unprognostic (2.18e-2)" "unprognostic (1.15e-1)" "unprognostic (6.47e-3)" "unprognostic (1.99e-1)" "prognostic favorable (3.08e-5)" "unprognostic (2.39e-2)" "unprognostic (6.57e-2)" "unprognostic (4.25e-2)" "unprognostic (8.51e-2)" 22.2 19.2 14.6 13.5 18.2 10.9 11.1 16.0 20.6 5.0 12.3 13.8 8.4 3.9 2.5 2.9 5.6 6.2 11.5 14.6 18.8 43.0 5.3 24.6 16.5 18.4 19.8 1.7 1.8 2.1 6.0 10.3 18.0 3.8 4.2 2.2 5.8 2.0 2.2 9.7 13.9 4.7 15.2 67.0 5.9 1.2 19.4 6.2 5.4 0.1 6.3 6.2 4.5 19.6 0.0 0.0 3.3 0.1 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 35.5 0.0 0.1 0.0 7.1 0.0 0.0 0.0 1.5 28.2 0.0 2.3 20.4 0.0 121.4 0.8 0.0 0.0 0.0 0.0 0.0 1.0 8.2 10.3 0.0 0.6 7.5 0.3 0.4 0.3 0.0 13.6 0.0 0.1 0.0 0.0 0.1 2.0 0.0 0.0 86.4 3.0 0.3 9.9 1.3 0.0 0.8 0.0 0.1 12.5 74.8 5.0 2.5 13.3 9.8 1.7 0.9 2.7 0.1 0.7 0.1 0.4 0.0 0.0 0.1 0.2 0.4 0.2 2.0 0.1 1.6 0.3 0.0 0.5 14.6 18.2 16.0 20.6 14.6 18.8 18.4 19.8 18.0 15.2 19.4 19.6 1.9 0.0 2.2 7.2 8.0 4.7 1.3 0.3 0.6 2.4 0.4 0.6 1.0 2.8 0.4 9.2 0.0 1.3 2.6 0.4 37.2 1.4 0.1 0.1 0.5 10.7 1.8 3.0 0.2 0.4 6.0 4.5 0.0 0.3 127.7 1.3 52.1 0.8 183.4 15.2 1.7 1.0 0.0 70.7 13.3 0.4 0.3 49.2 28.4 6.5 40.7 10.7 8.2 0.5 6.2 0.5 5.3 0.4 4.0 1.4 12.3 204.2 0.2 0.8 13.1 2.2 4.9 0.1 1.4 0.4 2.0 2.9 7.5 0.7 0.7 0.6 RNASE6 "RAD1, RNaseK6, RNS6" ENSG00000169413 "Ribonuclease A family member k6" Q93091 14 20781268-20782467 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 110.5" "Cell type enhanced" "Detected in many" "B-cells: 108.0;dendritic cells: 221.7;Hofbauer cells: 207.9;Kupffer cells: 551.2;Langerhans cells: 198.4;Macrophages: 270.3;monocytes: 115.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 1238.8" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 7 "RPMI-8226: 65.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA000698 Approved "Secreted to blood" NA NA 2600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA000698: AB_2181340" "unprognostic (5.04e-2)" "unprognostic (5.21e-3)" "unprognostic (3.59e-2)" "unprognostic (4.05e-2)" "unprognostic (1.74e-1)" "unprognostic (7.31e-2)" "unprognostic (7.91e-2)" "unprognostic (2.29e-1)" "unprognostic (4.45e-1)" "unprognostic (1.65e-1)" "unprognostic (2.04e-1)" "unprognostic (2.73e-1)" "unprognostic (2.85e-3)" "unprognostic (9.62e-2)" "unprognostic (5.60e-3)" "unprognostic (3.46e-2)" "unprognostic (5.54e-2)" 25.2 29.5 8.0 59.6 7.5 27.5 24.0 7.8 13.6 31.6 10.0 27.7 17.3 10.6 78.4 16.0 11.3 47.7 11.7 7.3 10.9 12.2 21.1 29.6 110.5 13.6 10.1 9.9 8.4 9.0 4.3 44.8 11.9 7.9 34.0 1.8 11.2 17.2 2.0 8.6 33.4 23.6 10.8 62.1 14.9 4.5 12.6 43.8 5.5 6.0 84.5 43.3 5.1 19.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 2.1 2.1 0.0 0.0 0.0 0.0 0.0 1.7 4.7 0.6 0.2 0.0 0.0 1.9 4.6 0.0 0.0 0.0 0.2 0.0 65.6 1.1 0.7 0.0 0.1 0.0 0.0 0.1 0.1 0.0 8.1 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.7 0.0 441.1 537.3 12.8 5.3 124.8 12.0 324.7 13.6 5.6 513.3 410.3 6.4 1.0 199.0 36.7 2.0 1238.8 1.1 329.8 8.0 7.5 7.8 13.6 7.3 10.9 13.6 10.1 11.9 10.8 12.6 19.5 1.6 6.4 7.5 0.0 108.0 4.5 0.2 0.0 1.8 0.0 1.4 2.8 0.6 14.3 1.2 0.0 0.0 1.1 221.7 2.6 0.0 0.0 0.8 0.1 0.0 3.8 0.0 12.0 0.0 0.0 1.6 1.4 1.1 0.2 0.0 0.0 8.6 3.3 207.9 0.0 0.0 0.5 2.0 551.2 198.4 4.8 2.8 270.3 21.4 1.9 115.8 0.0 9.2 0.0 0.0 0.0 12.6 0.7 52.4 0.2 0.4 0.5 0.2 0.4 13.1 0.6 0.6 0.1 0.7 0.6 3.8 2.2 7.8 0.0 3.4 1.2 SCIMP "C17orf87, DTFT5783, FLJ32580, MGC163426, MGC163428, UNQ5783" ENSG00000161929 "SLP adaptor and CSK interacting membrane protein" Q6UWF3 17 5208920-5234860 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 49.2" "Cell type enhanced" "Detected in many" "B-cells: 66.4;Hofbauer cells: 26.2;Kupffer cells: 120.3;Macrophages: 66.3;monocytes: 60.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 2.7" "Group enriched" "Detected in many" 8 "classical monocyte: 110.6;intermediate monocyte: 239.0;memory B-cell: 145.8;myeloid DC: 84.2;naive B-cell: 124.5;non-classical monocyte: 265.5" "Group enriched" "Detected in all" 9 "B-cells: 145.8;dendritic cells: 84.2;monocytes: 265.5" "Cell line enhanced" "Detected in many" "HeLa: 6.8;U-698: 10.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006117 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA006117: AB_1858633" "unprognostic (2.53e-2)" "unprognostic (7.88e-3)" "unprognostic (1.26e-2)" "unprognostic (5.79e-3)" "unprognostic (1.10e-1)" "unprognostic (3.87e-2)" "unprognostic (7.96e-2)" "unprognostic (1.73e-2)" "unprognostic (4.93e-2)" "unprognostic (2.99e-1)" "unprognostic (1.35e-1)" "unprognostic (8.05e-2)" "unprognostic (3.33e-2)" "unprognostic (2.07e-1)" "unprognostic (4.42e-2)" "unprognostic (1.77e-1)" "unprognostic (9.95e-2)" 5.9 4.1 0.0 30.4 0.1 5.1 1.4 2.7 1.3 1.5 3.6 4.5 5.4 2.9 1.1 1.9 3.1 7.3 1.7 0.3 0.0 2.3 10.6 16.2 39.4 0.6 0.1 3.6 3.9 0.8 0.7 3.9 0.1 3.1 4.6 7.5 4.0 1.4 4.3 3.2 10.2 6.1 0.0 49.2 5.0 2.8 0.0 5.1 3.4 0.8 44.9 6.0 0.6 0.4 1.0 1.5 2.5 3.3 0.0 0.0 2.5 1.1 0.0 0.0 0.0 0.7 2.1 4.8 0.9 0.0 1.8 1.0 0.0 0.0 0.0 0.8 2.1 2.0 6.8 0.7 0.0 0.2 0.7 0.0 0.1 0.0 0.2 1.2 0.0 4.2 0.1 1.2 0.0 1.6 2.4 0.7 1.1 0.3 1.4 2.2 0.5 0.5 0.0 0.6 1.8 0.8 1.8 0.6 1.3 0.7 2.6 2.4 0.3 0.3 1.1 1.4 0.6 0.7 0.3 10.8 1.2 0.3 0.7 16.8 110.6 3.0 1.3 239.0 1.5 145.8 0.8 1.2 84.2 124.5 1.7 1.2 19.0 5.3 265.5 3.2 1.4 68.0 0.0 0.1 2.7 1.3 0.3 0.0 0.6 0.1 0.1 0.0 0.0 0.4 0.5 0.0 4.4 2.6 66.4 0.4 0.4 0.0 0.0 2.5 0.4 0.5 0.4 1.5 0.6 0.0 12.5 0.3 1.5 0.0 0.0 0.7 1.4 0.4 0.3 2.0 0.0 0.4 6.5 0.9 0.3 0.6 0.0 0.1 1.3 0.4 3.3 1.9 26.2 1.7 4.9 0.0 0.0 120.3 4.2 0.7 0.3 66.3 0.0 8.4 60.3 0.4 10.3 4.0 2.3 0.4 0.0 0.4 1.7 0.3 0.0 1.0 1.6 4.1 0.0 0.7 0.3 0.5 0.8 0.0 0.4 0.1 3.2 0.2 0.0 0.4 SIGLEC7 "CD328, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2" ENSG00000168995 "Sialic acid binding Ig like lectin 7" Q9Y286 19 51142299-51153526 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 31.3;Kupffer cells: 57.4;Macrophages: 33.1;monocytes: 15.5;NK-cells: 69.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 242.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Karpas-707: 55.4;RPMI-8226: 33.7;U-937: 35.0" HPA075513 Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 2600000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" Vesicles "HPA075513: " "unprognostic (3.14e-1)" "unprognostic (5.87e-2)" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (3.90e-2)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (2.78e-1)" "unprognostic (1.69e-1)" "unprognostic (4.95e-2)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.27e-2)" "unprognostic (6.61e-2)" "unprognostic (1.14e-3)" "unprognostic (2.58e-1)" "unprognostic (2.26e-2)" 3.7 2.9 0.9 10.6 1.0 4.6 1.0 1.0 1.9 0.6 1.2 1.9 1.6 0.5 0.4 0.4 1.2 2.6 1.3 0.8 1.3 1.6 7.4 5.0 7.7 2.1 1.5 0.4 0.5 0.7 0.6 6.2 1.9 0.7 2.4 0.2 0.7 0.4 0.2 0.2 2.2 3.8 1.4 19.2 0.9 0.9 2.2 1.5 0.5 0.3 2.4 3.1 0.5 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.4 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.1 33.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.1 0.0 1.2 1.1 0.0 0.2 35.0 0.0 3.2 140.2 242.1 10.6 105.8 18.9 3.8 0.2 4.8 65.5 0.2 0.3 4.4 116.7 96.8 44.0 2.9 0.0 80.9 0.9 1.0 1.0 1.9 0.8 1.3 2.1 1.5 1.9 1.4 2.2 2.4 0.4 0.0 2.2 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 1.8 0.0 0.2 8.3 0.1 0.0 0.0 0.4 0.0 0.2 0.6 0.0 8.8 0.0 0.0 0.2 0.3 0.0 0.0 1.3 0.0 6.1 0.8 31.3 0.0 0.0 0.0 0.0 57.4 3.5 0.0 1.5 33.1 0.0 0.0 15.5 0.0 69.0 0.0 0.0 0.1 0.0 1.2 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 3.5 0.4 0.0 0.0 SLAMF8 "BLAME, CD353, SBBI42" ENSG00000158714 "SLAM family member 8" Q9P0V8 1 159826811-159837492 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 32.9" "Group enriched" "Detected in some" 9 "Hofbauer cells: 36.9;Kupffer cells: 19.8;Langerhans cells: 61.8;Macrophages: 41.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 14.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC TERT1: 1.7;HL-60: 1.4;U-138 MG: 1.9;U-87 MG: 1.0;U-937: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA067601 Enhanced NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA067601: AB_2685870" "unprognostic (1.04e-1)" "unprognostic (8.80e-3)" "unprognostic (5.12e-2)" "unprognostic (2.14e-3)" "unprognostic (3.07e-2)" "unprognostic (3.22e-2)" "unprognostic (7.87e-2)" "unprognostic (4.29e-1)" "unprognostic (2.20e-2)" "unprognostic (4.56e-2)" "unprognostic (6.47e-2)" "unprognostic (1.77e-1)" "prognostic unfavorable (5.42e-5)" "unprognostic (3.50e-1)" "unprognostic (4.42e-2)" "unprognostic (2.01e-1)" "unprognostic (1.04e-1)" 6.9 3.7 1.7 29.8 1.8 0.9 3.0 1.8 3.6 3.8 2.9 7.6 6.6 1.5 0.7 4.2 2.8 8.0 2.6 1.4 2.3 3.9 3.3 16.1 32.9 4.9 3.9 2.8 2.1 0.6 3.5 5.5 5.3 2.5 9.5 0.3 3.4 1.4 0.9 2.8 9.3 7.6 2.5 11.7 4.9 0.8 9.2 10.5 3.0 0.6 17.7 10.3 2.1 4.9 0.0 0.0 0.0 0.0 0.2 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 1.4 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 1.9 0.0 0.0 0.3 0.0 0.0 0.0 1.0 1.2 0.0 0.0 5.8 0.0 3.5 8.0 0.2 0.0 1.2 4.6 14.3 0.0 0.2 2.7 0.5 8.8 0.5 0.1 0.0 3.1 1.7 1.8 1.8 3.6 1.4 2.3 4.9 3.9 5.3 2.5 9.2 4.9 0.3 0.0 2.3 0.0 1.0 1.8 0.0 0.0 0.0 0.4 0.1 0.4 0.3 0.0 0.6 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.3 0.1 0.8 0.0 0.4 0.1 0.2 0.3 0.3 0.0 0.1 0.0 0.1 0.0 0.2 36.9 0.0 0.1 0.0 0.0 19.8 61.8 0.0 0.3 41.1 0.0 1.0 1.3 0.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 2.9 0.1 0.0 0.0 1.0 0.5 1.3 0.0 0.0 0.0 SLC7A7 "LPI, y+LAT-1" ENSG00000155465 "Solute carrier family 7 member 7" Q9UM01 14 22773222-22829820 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 131.6;kidney: 300.6" "Group enriched" "Detected in many" 4 "Hofbauer cells: 216.5;Kupffer cells: 410.6;Macrophages: 146.2;monocytes: 164.0;Proximal enterocytes: 423.1;Proximal tubular cells: 327.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 299.9;intermediate monocyte: 410.0;non-classical monocyte: 457.1" "Lineage enriched" "Detected in many" 5 "monocytes: 457.1" "Group enriched" "Detected in many" 4 "BEWO: 217.2;CACO-2: 385.7;OE19: 329.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036227 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036227: AB_10696653" "unprognostic (1.34e-1)" "unprognostic (7.65e-2)" "unprognostic (4.25e-2)" "unprognostic (2.52e-1)" "unprognostic (6.12e-2)" "unprognostic (3.69e-2)" "unprognostic (7.84e-3)" "unprognostic (1.47e-1)" "unprognostic (2.88e-2)" "unprognostic (1.73e-2)" "unprognostic (2.60e-3)" "unprognostic (7.15e-2)" "prognostic unfavorable (6.28e-6)" "unprognostic (2.68e-3)" "unprognostic (1.86e-2)" "unprognostic (2.61e-1)" "unprognostic (1.12e-1)" 15.1 9.0 3.1 37.4 3.2 19.7 6.8 3.8 7.5 7.3 4.3 13.8 107.0 5.3 2.0 3.7 7.8 17.0 5.1 2.8 3.8 300.6 16.4 54.1 29.1 6.9 4.7 2.1 5.2 78.4 1.4 18.2 6.4 3.5 15.0 1.0 5.4 2.8 2.0 3.2 131.6 15.6 5.1 56.8 8.6 32.8 7.1 9.6 4.6 2.8 25.2 14.7 4.1 8.1 0.2 11.2 1.2 0.5 1.9 3.7 217.2 2.2 16.3 0.4 1.4 385.7 34.4 17.0 72.2 1.4 1.2 13.3 0.1 0.0 0.6 0.6 0.2 0.9 0.4 3.7 9.1 1.9 1.6 7.1 1.0 1.0 0.5 1.8 25.3 1.5 0.1 12.8 2.9 0.6 0.4 1.7 3.6 329.0 0.1 2.9 35.5 9.8 0.8 1.3 0.4 0.8 0.6 0.5 2.5 9.4 0.4 8.3 1.3 0.8 1.7 0.6 0.5 2.7 0.9 8.9 0.9 0.8 0.2 0.2 299.9 1.1 0.5 410.0 0.4 19.1 0.2 0.2 99.5 13.8 0.7 0.4 36.5 0.3 457.1 3.4 0.9 155.1 3.1 3.2 3.8 7.5 2.8 3.8 6.9 4.7 6.4 5.1 7.1 8.1 5.3 12.8 7.1 2.0 14.3 1.0 0.2 6.7 1.8 0.2 0.5 1.7 0.9 67.2 5.6 3.7 0.0 1.2 5.7 3.0 11.7 8.2 61.1 1.7 1.2 5.0 1.2 0.0 0.6 6.4 5.2 4.4 2.6 0.4 1.3 0.7 16.1 3.0 216.5 0.0 1.4 7.2 2.0 410.6 16.8 11.8 3.7 146.2 5.4 20.6 164.0 0.4 4.1 0.0 0.8 8.9 12.5 0.0 20.1 0.1 423.1 327.6 9.2 1.3 6.6 0.8 1.4 17.8 2.2 0.4 0.4 1.8 2.7 38.8 6.4 0.1 SLCO2B1 "OATP-B, OATP2B1, SLC21A9" ENSG00000137491 "Solute carrier organic anion transporter family member 2B1" O94956 11 75100563-75206549 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 229.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 204.5;Hofbauer cells: 122.2;Kupffer cells: 155.8;Macrophages: 92.4;Microglial cells: 232.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 90.3;GAMG: 21.2;Hep G2: 20.4;HMC-1: 25.8;OE19: 111.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020659 Uncertain NA NA "Cluster 15: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 4: Macrophages - Innate immune response" "HPA020659: AB_1857219" "unprognostic (8.25e-2)" "unprognostic (5.30e-2)" "unprognostic (2.02e-2)" "unprognostic (3.57e-1)" "unprognostic (3.40e-1)" "unprognostic (1.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.09e-1)" "unprognostic (2.61e-1)" "unprognostic (2.00e-3)" "unprognostic (1.99e-1)" "unprognostic (2.09e-1)" "unprognostic (9.75e-3)" "unprognostic (2.54e-2)" "unprognostic (4.57e-3)" "unprognostic (1.04e-1)" "unprognostic (3.87e-2)" 39.9 31.5 40.1 34.0 35.9 2.9 12.1 34.0 37.4 18.1 21.3 30.9 42.1 9.5 3.6 19.7 13.2 28.4 15.6 31.9 47.2 21.0 229.6 60.7 60.1 75.7 53.4 9.4 22.1 7.9 5.1 43.9 63.0 6.1 23.6 1.5 8.4 9.6 5.6 4.3 51.3 26.3 49.7 46.4 15.0 6.0 80.4 16.7 10.1 8.0 28.5 26.3 6.2 55.1 0.0 0.7 2.8 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 90.3 0.0 0.1 0.1 0.0 21.2 0.2 0.0 0.0 0.0 1.1 0.0 15.0 1.0 20.4 0.0 1.1 25.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.3 8.7 0.0 0.1 0.0 0.1 0.1 111.1 0.0 0.0 2.4 9.6 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.8 0.0 0.0 1.9 0.0 0.1 0.3 0.0 1.5 1.8 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.1 35.9 34.0 37.4 31.9 47.2 75.7 53.4 63.0 49.7 80.4 55.1 4.7 0.0 8.9 1.3 0.7 1.9 0.0 0.0 1.8 3.4 0.9 1.4 2.8 11.5 1.8 0.0 0.0 0.9 0.1 14.7 1.9 0.0 2.8 0.0 0.1 28.8 0.0 2.7 0.5 0.2 2.3 3.6 0.5 0.0 22.9 6.1 3.6 204.5 122.2 0.0 0.5 6.6 0.0 155.8 8.9 1.7 10.8 92.4 0.0 232.3 2.0 0.2 0.0 1.5 0.6 0.1 14.6 10.5 1.4 0.0 46.7 8.2 0.7 0.7 0.0 3.0 1.1 0.4 0.2 4.5 0.4 2.5 0.7 0.4 13.3 0.1 SOWAHD ANKRD58 ENSG00000187808 "Sosondowah ankyrin repeat domain family member D" A6NJG2 X 119758588-119760202 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.1;lymphoid tissue: 7.1;testis: 5.0" "Cell type enhanced" "Detected in some" "B-cells: 12.2;Extravillous trophoblasts: 38.3;Hofbauer cells: 17.5;Proximal enterocytes: 9.1;Rod photoreceptor cells: 8.2;Syncytiotrophoblasts: 9.4" "Cancer enriched" "Detected in many" 6 "testis cancer: 8.5" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive B-cell: 11.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 4.3;NB-4: 2.9;SK-BR-3: 3.2;THP-1: 8.3;U-937: 7.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA065955 Uncertain NA NA "Cluster 24: B-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA065955: AB_2685586" "unprognostic (1.78e-2)" "unprognostic (9.37e-2)" "unprognostic (3.10e-2)" "unprognostic (8.88e-2)" "unprognostic (1.67e-1)" "unprognostic (4.38e-2)" "unprognostic (2.03e-1)" "unprognostic (7.20e-2)" "unprognostic (3.45e-2)" "unprognostic (6.07e-2)" "unprognostic (5.80e-2)" "unprognostic (2.41e-2)" "unprognostic (1.04e-5)" "unprognostic (5.82e-2)" "unprognostic (3.14e-2)" "unprognostic (9.22e-2)" "unprognostic (3.74e-3)" 0.3 0.4 0.7 1.8 0.6 2.1 0.2 0.6 0.9 0.2 0.3 1.2 2.1 0.1 0.0 0.2 0.3 0.2 0.2 0.6 0.6 1.1 0.3 1.6 2.5 1.1 0.6 0.3 0.3 0.7 0.1 1.1 0.9 0.2 0.5 0.7 1.7 0.1 0.0 0.3 4.1 0.1 1.0 7.1 1.2 5.0 1.1 0.6 0.1 0.2 1.5 0.3 0.1 1.5 0.4 0.0 0.1 0.1 0.0 0.0 4.3 0.0 0.0 0.4 0.6 0.8 0.1 0.2 0.6 0.0 0.5 0.0 0.0 0.0 0.1 0.7 0.5 0.0 0.0 1.2 0.2 0.8 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.4 0.0 2.9 0.9 0.8 0.3 2.5 0.1 0.1 0.0 0.1 0.2 0.1 0.9 3.2 0.1 0.3 0.5 8.3 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.1 0.0 7.4 0.0 0.0 3.1 1.9 0.0 3.3 0.0 9.1 0.4 0.3 2.0 11.7 1.7 0.9 3.3 0.3 2.9 1.0 0.0 0.7 0.7 0.6 0.6 0.9 0.6 0.6 1.1 0.6 0.9 1.0 1.1 1.5 0.2 0.0 0.0 0.0 12.2 0.0 0.1 0.0 0.0 0.8 0.3 0.5 0.5 1.5 0.0 3.7 0.0 6.1 2.7 3.7 0.0 0.4 0.6 0.1 0.0 0.4 0.0 0.0 0.0 0.4 38.3 0.1 0.5 0.2 0.0 0.2 0.0 0.0 17.5 1.7 0.0 0.9 0.0 5.4 0.6 1.2 0.0 6.5 0.0 0.0 3.4 0.6 1.0 0.0 0.0 0.0 0.5 0.0 1.1 0.0 9.1 0.2 0.0 8.2 0.0 0.0 0.2 0.1 0.9 0.1 0.1 9.4 0.5 0.1 2.3 0.0 TMEM150B "DRAM3, TMEM224, TTN2" ENSG00000180061 "Transmembrane protein 150B" A6NC51 19 55312801-55334048 "Predicted membrane proteins, Transporters" Autophagy "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "intestine: 64.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 18.1;Kupffer cells: 11.8;monocytes: 8.0;Proximal enterocytes: 68.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.7" "Group enriched" "Detected in many" 7 "granulocytes: 1.9;monocytes: 5.7" "Cell line enhanced" "Detected in some" "CACO-2: 8.3;HMC-1: 3.8;THP-1: 2.9;U-937: 18.1" "Not detected" "Not detected" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 32: U-937 - Innate immune response" "Cluster 45: Enterocytes - Digestion" "unprognostic (3.19e-2)" "unprognostic (1.00e-1)" "unprognostic (5.76e-2)" "unprognostic (4.94e-2)" "unprognostic (5.33e-2)" "unprognostic (6.70e-2)" "unprognostic (5.51e-2)" "unprognostic (1.35e-1)" "unprognostic (5.35e-2)" "unprognostic (4.00e-2)" "unprognostic (4.74e-2)" "unprognostic (3.06e-1)" "prognostic unfavorable (6.14e-6)" "unprognostic (1.48e-1)" "unprognostic (1.63e-3)" "unprognostic (2.45e-1)" "unprognostic (1.18e-2)" 3.7 1.8 0.5 5.8 0.8 0.7 1.1 0.4 1.0 0.3 1.2 10.2 64.1 0.4 0.1 0.6 0.8 2.9 0.8 0.4 0.7 3.2 2.2 11.9 3.5 1.3 0.7 0.3 0.9 0.1 0.2 5.6 1.6 0.3 7.3 0.0 0.6 0.4 0.2 0.2 57.0 4.1 0.5 5.7 1.4 0.5 3.4 0.7 0.3 0.2 1.6 2.0 0.3 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 1.6 0.0 1.1 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.9 0.0 0.0 0.1 0.1 0.1 1.8 0.0 0.2 0.0 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 2.9 0.1 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 18.1 0.1 1.9 5.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.5 0.8 0.4 1.0 0.4 0.7 1.3 0.7 1.6 0.5 3.4 1.3 0.0 0.0 0.0 0.0 0.6 0.1 1.3 0.0 0.0 0.0 0.1 0.0 0.5 1.5 0.0 1.8 0.0 0.0 0.0 18.1 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.8 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.1 6.7 0.0 0.7 3.5 0.0 11.8 1.3 0.0 0.0 3.2 0.0 0.0 8.0 0.0 0.0 0.0 0.9 0.3 1.4 0.0 0.9 0.6 68.9 0.6 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 3.7 0.3 TNFAIP8L2 FLJ23467 ENSG00000163154 "TNF alpha induced protein 8 like 2" Q6P589 1 151156649-151159749 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 70.4;Kupffer cells: 65.4;Macrophages: 35.8;monocytes: 34.7;NK-cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 29.8;HL-60: 17.6;HMC-1: 44.1;NB-4: 25.2;THP-1: 95.2;U-937: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062742 Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA062742: " "unprognostic (3.19e-3)" "unprognostic (1.02e-2)" "unprognostic (6.63e-3)" "unprognostic (2.27e-2)" "unprognostic (1.29e-1)" "unprognostic (6.49e-3)" "unprognostic (1.05e-1)" "unprognostic (9.15e-3)" "prognostic favorable (3.64e-4)" "unprognostic (9.54e-2)" "unprognostic (3.32e-2)" "unprognostic (9.03e-2)" "prognostic unfavorable (3.53e-7)" "unprognostic (1.78e-1)" "unprognostic (3.91e-2)" "unprognostic (4.87e-2)" "unprognostic (2.23e-1)" 4.7 4.3 4.9 19.6 5.4 6.1 3.4 5.1 7.5 2.3 5.7 4.5 5.3 1.5 1.4 2.5 2.2 5.5 2.3 4.7 5.2 2.0 5.6 10.8 32.0 6.5 5.7 1.0 1.4 1.2 1.2 6.9 7.0 2.1 6.1 0.9 2.6 1.8 0.8 3.8 7.6 5.4 6.4 39.2 3.4 0.8 6.3 19.2 1.3 2.2 17.7 7.8 1.4 8.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 29.8 0.4 0.0 0.0 17.6 44.1 0.0 0.0 0.0 0.0 0.0 0.4 2.5 0.1 0.1 0.0 0.1 0.4 25.2 0.0 0.0 0.1 5.3 0.1 4.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 95.2 2.5 0.2 0.1 0.1 0.2 0.3 0.0 1.9 0.1 37.8 0.1 317.0 238.8 246.7 103.2 220.2 101.9 78.3 125.7 105.2 265.4 83.2 189.5 137.3 292.3 232.9 210.6 63.0 155.7 249.5 4.9 5.4 5.1 7.5 4.7 5.2 6.5 5.7 7.0 6.4 6.3 8.1 0.3 0.0 1.7 0.0 6.9 0.3 0.0 0.0 0.0 0.8 0.8 0.3 0.1 2.8 1.3 0.0 0.0 0.3 11.1 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 8.8 0.0 0.0 0.5 0.2 0.0 0.0 5.1 0.0 0.7 0.3 70.4 0.0 0.0 0.0 0.0 65.4 12.8 0.4 0.3 35.8 0.0 0.0 34.7 0.0 48.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 1.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.4 10.6 0.0 0.0 0.0 TREM2 "TREM-2, Trem2a, Trem2b, Trem2c" ENSG00000095970 "Triggering receptor expressed on myeloid cells 2" Q9NZC2 6 41158506-41163186 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.8;lung: 30.1" "Cell type enriched" "Detected in many" 8 "Hofbauer cells: 1014.1" "Cancer enhanced" "Detected in all" "glioma: 93.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.0" "Lineage enhanced" "Detected in single" "dendritic cells: 2.0" "Group enriched" "Detected in some" 4 "hTCEpi: 74.6;THP-1: 42.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010917, HPA012571" Approved "Secreted in brain" NA NA 50000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "HPA010917: AB_1080365, HPA012571: AB_1858260" "unprognostic (3.89e-1)" "unprognostic (4.44e-3)" "unprognostic (2.77e-2)" "unprognostic (1.80e-2)" "unprognostic (1.29e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (4.83e-2)" "unprognostic (1.07e-1)" "unprognostic (8.57e-3)" "unprognostic (1.33e-1)" "unprognostic (2.09e-1)" "unprognostic (3.58e-3)" "unprognostic (8.04e-2)" "unprognostic (1.04e-2)" "unprognostic (3.16e-3)" "unprognostic (1.85e-2)" 10.7 13.2 28.1 3.5 31.1 0.2 9.8 33.7 61.5 6.5 29.1 3.5 0.9 1.6 2.3 0.6 7.4 9.7 2.1 27.5 32.3 1.3 2.3 30.1 2.6 44.5 34.4 2.4 3.9 7.4 3.9 10.7 42.7 2.0 4.3 1.9 6.0 3.1 0.4 0.5 1.4 4.5 46.7 0.5 2.5 0.7 43.5 1.8 1.7 0.0 0.4 4.5 0.6 69.8 0.0 0.3 0.0 0.0 0.1 0.3 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 1.2 74.6 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 42.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 28.1 31.1 33.7 61.5 27.5 32.3 44.5 34.4 42.7 46.7 43.5 69.8 1.8 6.4 7.5 0.0 0.7 0.8 0.2 79.8 0.0 0.3 1.8 58.8 0.1 1.5 9.6 0.0 0.0 5.0 0.4 0.0 0.0 0.0 0.6 0.0 0.1 10.4 0.0 0.0 0.0 0.0 4.9 1.2 0.0 0.0 2.5 0.0 2.2 0.2 1014.1 0.0 0.0 0.0 2.0 34.7 5.2 1.0 0.6 120.5 0.0 12.2 8.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 3.3 1.0 6.6 0.1 1.0 0.0 0.0 0.0 0.1 7.3 0.8 0.0 0.0 0.1 VSIG4 "CRIg, Z39IG" ENSG00000155659 "V-set and immunoglobulin domain containing 4" Q9Y279 X 66021738-66040125 "Plasma proteins, Predicted membrane proteins" "Complement alternate pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 166.0" "Group enriched" "Detected in many" 5 "Hofbauer cells: 989.8;Kupffer cells: 590.9;Macrophages: 328.4" "Cancer enriched" "Detected in all" 5 "glioma: 88.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "classical monocyte: 18.7;intermediate monocyte: 11.1;myeloid DC: 17.8" "Group enriched" "Detected in many" 31 "dendritic cells: 17.8;monocytes: 18.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003903, CAB026000" Enhanced Uncertain "Nucleoli,Plasma membrane,Cytosol" NA NA 59000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" Nucleoli "CAB026000: , HPA003903: AB_1858776" "unprognostic (6.87e-3)" "unprognostic (4.79e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (3.19e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-2)" "unprognostic (9.37e-3)" "unprognostic (1.24e-1)" "unprognostic (3.10e-1)" "unprognostic (1.37e-3)" "unprognostic (1.06e-1)" "unprognostic (2.77e-1)" "prognostic unfavorable (1.95e-6)" "unprognostic (3.70e-2)" "unprognostic (5.45e-2)" "unprognostic (3.37e-2)" "unprognostic (3.47e-2)" 137.1 68.8 17.9 44.2 18.8 7.8 44.2 17.0 36.6 14.1 21.5 40.9 22.5 15.5 5.3 15.4 66.8 39.6 30.0 18.2 18.3 17.9 51.0 166.0 27.8 25.1 23.6 12.9 14.3 6.8 7.0 139.6 25.8 10.6 31.7 2.2 24.5 9.3 8.2 10.8 43.9 108.3 18.9 69.3 22.9 7.3 37.6 5.4 12.3 12.5 1.8 61.5 11.6 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 18.7 0.1 0.0 11.1 0.0 0.0 0.0 0.2 17.8 0.1 0.0 0.0 0.5 0.0 0.4 0.1 0.0 5.6 17.9 18.8 17.0 36.6 18.2 18.3 25.1 23.6 25.8 18.9 37.6 26.7 1.3 3.2 16.1 0.0 1.2 2.3 0.3 0.0 0.0 0.0 2.6 0.5 1.8 7.2 3.1 0.0 0.0 5.3 0.3 0.0 0.0 0.1 7.9 0.0 0.0 10.4 0.0 0.0 0.0 0.0 4.9 2.7 0.0 0.0 3.8 0.0 5.0 3.2 989.8 0.0 0.0 0.0 0.0 590.9 111.8 16.6 1.5 328.4 3.6 12.2 1.5 0.5 0.0 0.5 0.0 0.0 0.1 0.4 0.3 0.3 0.0 0.1 4.4 0.0 6.6 0.6 2.0 0.3 0.9 0.5 1.7 12.3 1.5 0.0 0.0 0.2