Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ACTN1 ENSG00000072110 "Actinin alpha 1" P12814 14 68874128-68979440 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "smooth muscle: 524.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 351.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 364.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004303, HPA006035" Approved Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 210000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Actin filaments, Focal adhesion sites" "CAB004303: AB_626633, HPA006035: AB_1078095" "unprognostic (4.40e-2)" "unprognostic (1.03e-3)" "unprognostic (2.49e-2)" "unprognostic (1.96e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (6.19e-3)" "prognostic unfavorable (7.63e-5)" "unprognostic (3.62e-1)" "unprognostic (3.23e-2)" "unprognostic (3.16e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (9.08e-10)" "unprognostic (2.87e-2)" "unprognostic (2.00e-1)" "unprognostic (6.05e-3)" "prognostic unfavorable (8.00e-4)" 117.4 40.7 27.3 149.5 55.8 149.3 103.5 0.1 32.0 118.4 20.1 449.8 49.8 313.1 60.3 154.4 152.1 143.9 121.4 29.7 14.7 46.7 61.8 100.0 47.5 24.5 11.0 61.8 46.8 9.1 27.3 96.1 7.3 174.3 109.0 28.2 116.4 295.1 21.7 59.3 106.9 524.5 4.2 55.9 171.7 21.2 32.9 32.6 35.0 13.3 50.7 305.9 83.3 28.8 871.9 262.3 158.6 121.4 275.2 180.5 592.4 749.3 712.0 770.0 571.1 211.8 196.6 0.7 256.5 744.7 310.4 370.9 126.8 790.3 965.2 4.6 38.5 118.2 133.5 179.0 494.0 85.4 14.3 231.7 152.1 479.8 540.3 551.6 428.6 48.2 56.9 1.4 612.0 246.9 10.1 181.1 124.7 217.9 198.1 59.3 294.1 32.6 292.0 225.6 57.0 68.7 649.9 96.8 177.1 474.8 146.0 170.9 546.0 1085.2 432.8 126.9 662.5 113.8 47.8 3.9 314.4 115.7 584.4 64.6 67.5 137.1 5.7 28.8 7.1 0.1 22.7 12.4 45.5 0.2 103.9 92.2 364.2 4.5 8.9 2.0 9.6 89.2 27.3 55.8 0.1 32.0 29.7 14.7 24.5 11.0 7.3 4.2 32.9 28.8 44.7 38.5 25.1 19.6 4.0 119.3 154.9 137.4 82.0 74.7 88.6 157.6 60.3 51.5 36.0 42.3 246.0 155.3 3.0 17.2 3.9 186.8 34.0 65.8 112.8 135.5 38.5 21.9 102.7 144.9 351.8 88.9 34.1 90.2 7.6 15.9 129.5 96.6 79.5 18.5 29.7 57.3 59.0 100.9 82.1 10.7 35.8 96.4 30.2 34.7 105.1 6.0 4.1 9.0 4.3 203.7 28.0 245.6 0.6 132.6 2.4 15.3 47.8 80.8 177.5 30.0 270.6 19.4 18.4 51.8 59.8 66.9 22.7 20.9 47.0 67.1 ASB2 ASB-2 ENSG00000100628 "Ankyrin repeat and SOCS box containing 2" Q96Q27 14 93934166-93976739 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 522.2;tongue: 157.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 51.1;Early spermatids: 26.4;Late spermatids: 29.9;Skeletal myocytes: 27.6;T-cells: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 7 "eosinophil: 50.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 50.8" "Cell line enhanced" "Detected in some" "Karpas-707: 12.8;RPMI-8226: 12.4;SK-MEL-30: 5.9;U-266/70: 42.1;U-266/84: 8.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001546 Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA001546: AB_1078224" "unprognostic (5.65e-4)" "unprognostic (8.19e-2)" "unprognostic (1.31e-1)" "prognostic favorable (3.62e-6)" "unprognostic (4.11e-2)" "unprognostic (1.61e-1)" "unprognostic (5.29e-2)" "unprognostic (1.05e-3)" "unprognostic (4.25e-2)" "unprognostic (1.48e-2)" "unprognostic (2.51e-2)" "unprognostic (1.89e-1)" "unprognostic (2.49e-7)" "unprognostic (2.51e-3)" "unprognostic (2.12e-1)" "unprognostic (2.01e-2)" "unprognostic (2.27e-1)" 2.9 0.8 0.8 5.6 2.1 0.5 1.5 0.0 1.9 12.0 0.0 66.5 4.0 31.6 0.3 4.0 26.6 0.5 78.5 0.6 0.0 0.5 0.5 3.0 7.4 0.1 0.0 2.9 0.3 0.2 0.2 0.2 0.3 14.4 0.4 0.0 6.6 0.9 522.2 2.3 18.3 1.6 0.0 4.2 17.2 0.4 0.3 0.4 1.2 157.6 3.2 30.4 8.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 1.3 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 0.0 0.4 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.1 0.0 12.4 0.0 0.2 0.1 0.0 0.0 0.0 5.9 0.0 0.0 2.9 0.0 0.0 0.0 0.2 0.0 42.1 8.6 1.7 0.5 2.6 0.5 0.0 0.2 50.8 1.9 2.7 0.3 1.9 1.7 3.8 4.2 0.4 0.2 0.5 0.1 0.0 7.8 0.4 2.3 1.3 0.8 2.1 0.0 1.9 0.6 0.0 0.1 0.0 0.3 0.0 0.3 0.1 0.2 0.0 0.0 0.3 3.3 0.4 0.1 8.4 0.0 0.2 0.2 0.9 51.1 0.0 2.9 0.0 0.0 0.1 3.0 0.0 0.0 1.4 26.4 1.7 0.3 0.5 0.0 2.7 4.7 0.0 0.5 1.9 1.1 2.5 0.0 0.0 0.0 0.0 0.6 0.0 1.9 0.0 0.0 0.0 0.3 29.9 0.3 5.3 1.8 1.9 5.8 0.8 2.1 0.0 0.7 0.2 0.0 0.4 10.7 0.1 0.0 0.0 0.4 1.1 0.0 27.6 5.0 0.8 8.4 0.1 0.1 2.9 14.5 0.1 0.1 0.3 BRSK1 KIAA1811 ENSG00000160469 "BR serine/threonine kinase 1" Q8TDC3 19 55282072-55312562 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 141.8;pituitary gland: 53.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 34.8;Excitatory neurons: 30.1;Horizontal cells: 38.7;Inhibitory neurons: 27.6;Oligodendrocyte precursor cells: 17.1;Oligodendrocytes: 29.4;Proximal enterocytes: 23.6" "Cancer enhanced" "Detected in all" "glioma: 12.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 56.4;SH-SY5Y: 51.8;WM-115: 46.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021212, HPA061719" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 65: Brain - Ion transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Cell Junctions" "HPA021212: AB_1845455, HPA061719: AB_2684593" "unprognostic (1.42e-3)" "unprognostic (2.92e-2)" "unprognostic (1.20e-1)" "unprognostic (6.69e-3)" "unprognostic (2.71e-1)" "unprognostic (4.21e-2)" "unprognostic (3.06e-6)" "unprognostic (4.24e-1)" "unprognostic (2.06e-2)" "unprognostic (3.04e-1)" "prognostic favorable (1.02e-4)" "unprognostic (3.00e-1)" "prognostic unfavorable (7.98e-6)" "unprognostic (1.16e-1)" "unprognostic (6.61e-3)" "unprognostic (1.34e-1)" "unprognostic (2.09e-1)" 1.5 12.0 75.0 3.7 90.1 0.5 2.6 47.5 141.8 5.9 0.0 11.8 3.8 8.3 4.0 3.2 5.4 4.4 12.8 103.2 66.1 2.4 0.7 1.9 2.7 70.4 54.8 5.5 2.8 16.9 53.0 1.1 66.8 8.3 1.6 20.4 2.3 5.0 0.7 1.5 4.7 5.6 32.9 1.8 4.9 11.4 74.1 2.3 3.1 1.4 1.4 6.3 4.6 105.5 0.8 2.8 33.2 17.6 0.1 1.4 0.3 5.9 7.7 7.1 10.3 13.1 5.9 7.0 3.7 6.2 6.6 0.3 7.0 0.3 6.6 33.3 28.0 4.6 4.0 1.4 7.0 1.5 12.8 4.6 0.6 7.3 0.0 27.4 0.3 17.9 6.6 40.8 6.5 1.9 9.0 1.7 24.9 0.7 2.3 20.4 8.5 1.1 0.5 0.0 56.4 51.8 0.1 1.0 12.8 9.2 2.9 3.8 0.0 13.7 15.2 7.7 10.8 37.9 28.0 16.6 13.8 3.1 46.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 75.0 90.1 47.5 141.8 103.2 66.1 70.4 54.8 66.8 32.9 74.1 105.5 0.3 0.0 1.3 9.4 5.2 0.1 1.0 0.1 1.2 34.8 0.9 2.2 1.2 0.0 0.6 1.8 2.1 0.0 1.2 10.4 0.0 0.4 1.2 0.3 3.8 0.9 3.5 0.0 30.1 0.0 0.0 1.2 0.5 0.3 0.0 2.3 0.0 0.0 1.6 38.7 27.6 1.6 0.0 6.6 0.4 0.3 0.6 1.0 0.0 1.0 2.3 4.1 3.1 17.1 29.4 0.5 0.1 4.9 9.8 1.0 23.6 0.9 0.2 10.1 0.0 0.6 2.1 3.9 7.0 0.0 0.0 0.0 1.1 2.8 1.9 0.2 CALD1 "CDM, H-CAD, L-CAD" ENSG00000122786 "Caldesmon 1" Q05682 7 134744252-134970729 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 916.1" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1190.3;Leydig cells: 1745.0;Peritubular cells: 2005.6;Sertoli cells: 2294.3;Smooth muscle cells: 2549.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "neutrophil: 1.9" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "BJ hTERT+: 736.3;fHDF/TERT166: 1202.8;U-138 MG: 733.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000006, HPA008066, HPA017330" Enhanced Enhanced "Plasma membrane,Actin filaments" Yes No 39000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Actin filaments" "CAB000006: AB_2065456, HPA008066: AB_1078378, HPA017330: AB_1845917" "unprognostic (2.16e-2)" "unprognostic (1.19e-2)" "unprognostic (2.80e-3)" "unprognostic (3.05e-2)" "unprognostic (4.51e-2)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (1.22e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (2.07e-1)" "unprognostic (1.27e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (6.52e-3)" "unprognostic (1.14e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-3)" 225.8 119.2 27.3 164.9 35.0 1.3 161.1 28.1 47.6 241.6 37.2 916.1 80.3 523.3 150.7 275.6 304.4 203.2 115.0 26.9 29.1 134.7 224.4 155.5 75.4 32.3 30.4 326.2 52.5 32.7 53.3 430.0 30.9 348.9 149.8 13.1 70.3 781.7 46.5 76.0 233.1 688.4 27.9 129.2 324.2 52.7 33.4 28.5 114.1 75.2 34.4 505.3 208.0 28.8 115.9 75.3 163.3 146.1 572.7 464.8 161.6 661.6 736.3 227.2 246.6 138.3 3.5 0.7 153.3 1202.8 148.1 26.9 106.0 202.3 308.4 1.5 38.9 4.0 87.8 94.7 375.6 1.5 0.8 360.9 153.6 252.8 147.4 343.6 193.0 0.0 0.6 1.6 338.7 0.3 0.6 3.2 197.7 0.1 25.6 1.4 146.6 2.3 46.9 32.2 29.0 72.1 235.3 31.7 90.0 491.0 7.2 1.4 508.5 733.2 130.0 143.8 230.3 0.9 1.1 1.3 259.0 0.8 573.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.9 0.2 0.0 0.0 0.0 2.9 27.3 35.0 28.1 47.6 26.9 29.1 32.3 30.4 30.9 27.9 33.4 28.8 400.6 22.4 17.6 43.1 7.3 420.4 379.6 218.8 164.4 172.0 115.5 466.1 456.5 228.8 33.5 44.1 6.2 202.7 5.0 0.3 23.5 392.6 61.0 89.4 1190.3 432.9 3.6 16.0 95.4 23.6 903.9 886.9 16.3 206.2 5.1 251.0 422.0 638.4 43.5 92.5 58.3 1.2 28.5 21.0 112.8 83.6 1745.0 38.8 336.2 94.6 8.4 140.6 6.2 98.5 158.8 146.0 0.2 2005.6 4.2 456.9 0.1 332.1 11.3 21.2 2294.3 326.1 2549.3 12.1 12.2 70.1 171.8 276.6 27.5 414.1 0.8 36.7 CAP2 ENSG00000112186 "Cyclase associated actin cytoskeleton regulatory protein 2" P40123 6 17393505-17557790 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 577.1;tongue: 313.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 126.5;Excitatory neurons: 158.1;Inhibitory neurons: 137.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 26.1;basal ganglia: 40.9;cerebral cortex: 87.2;hippocampal formation: 50.2;white matter: 32.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 101.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050530, HPA054147" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA050530: AB_2681159, HPA054147: AB_2682400" "unprognostic (7.27e-2)" "unprognostic (5.71e-3)" "unprognostic (1.63e-2)" "unprognostic (1.55e-1)" "unprognostic (4.86e-1)" "unprognostic (2.23e-2)" "unprognostic (9.94e-2)" "unprognostic (3.58e-2)" "unprognostic (7.72e-2)" "unprognostic (1.65e-1)" "unprognostic (6.43e-2)" "unprognostic (2.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.06e-2)" "unprognostic (1.47e-1)" "unprognostic (8.05e-2)" "unprognostic (1.75e-3)" 17.8 11.6 26.1 7.6 40.9 0.0 10.7 0.9 87.2 15.4 2.9 32.6 4.1 28.5 17.8 21.7 16.8 11.4 113.6 50.2 11.1 8.7 4.5 4.7 1.7 3.2 3.8 4.5 4.2 7.5 5.1 8.8 2.7 25.1 9.6 9.1 7.7 30.7 577.1 2.6 8.9 42.7 0.0 3.1 9.8 1.5 9.1 3.1 5.5 313.0 2.3 14.5 6.4 32.3 15.5 24.6 44.4 55.1 0.3 0.1 10.4 52.3 42.7 46.6 43.0 8.1 6.9 0.0 48.9 62.1 60.5 8.2 21.3 20.9 66.8 0.1 7.9 0.0 15.4 26.5 4.3 0.0 0.0 3.5 9.9 23.1 10.3 72.3 2.2 0.0 0.0 0.1 101.6 25.2 0.0 0.0 17.0 0.8 15.6 5.2 59.1 1.1 23.6 6.4 6.1 10.9 19.0 59.2 31.3 82.8 65.0 11.2 0.2 36.6 31.6 1.0 47.6 0.0 0.0 0.2 11.7 0.1 48.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.1 40.9 0.9 87.2 50.2 11.1 3.2 3.8 2.7 0.0 9.1 32.3 2.0 3.2 1.5 9.8 0.0 1.9 4.3 6.2 5.7 16.4 10.2 8.4 126.5 4.3 5.4 1.8 4.2 16.5 0.0 1.9 3.9 2.7 0.1 13.9 13.7 2.7 6.0 0.0 158.1 0.7 12.2 7.9 0.0 5.8 0.0 22.8 3.9 2.4 2.2 8.4 137.2 1.3 2.0 0.0 2.2 0.0 0.6 0.3 0.0 10.3 0.0 6.3 0.0 16.6 7.2 3.7 1.9 4.9 0.0 1.9 0.0 16.7 33.9 2.2 32.9 25.5 43.4 0.1 3.2 2.1 0.9 37.5 0.3 0.3 1.6 0.6 CASQ2 PDIB2 ENSG00000118729 "Calsequestrin 2" O14958 1 115700021-115768714 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1056.7" "Cell type enriched" "Detected in some" 8 "Cardiomyocytes: 777.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 19 "HSkMC: 13.6" "Region enriched" "Detected in all" 6 "cerebellum: 43.1" "Low region specificity" "Detected in all" "HPA027285, HPA055298" Enhanced "Intracellular and membrane" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA027285: AB_1845933, HPA055298: AB_2682777" "unprognostic (1.13e-1)" "unprognostic (1.52e-1)" "unprognostic (9.70e-3)" "unprognostic (1.28e-1)" "unprognostic (3.41e-2)" "prognostic unfavorable (2.30e-4)" "unprognostic (1.03e-4)" "unprognostic (1.78e-1)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (7.20e-3)" "unprognostic (1.82e-2)" "unprognostic (1.80e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.25e-5)" 31.9 3.0 3.5 6.4 2.3 0.0 8.9 2.8 4.0 8.0 2.0 59.8 3.3 17.2 6.5 38.5 14.7 6.6 1056.7 1.8 3.6 3.5 0.6 5.3 0.8 1.9 4.8 5.3 1.2 1.6 0.9 1.6 2.1 13.8 17.0 0.3 7.6 20.2 182.1 4.9 9.1 39.1 1.9 0.8 14.2 1.5 6.4 1.6 4.1 165.0 1.3 43.9 6.9 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 2.3 2.8 4.0 1.8 3.6 1.9 4.8 2.1 1.9 6.4 1.9 2.7 0.0 0.0 0.3 0.0 0.6 0.3 0.0 0.6 0.2 0.1 0.4 777.8 0.0 0.0 1.8 0.0 0.4 0.1 0.0 0.0 0.0 15.5 0.3 0.0 4.8 0.0 0.0 0.7 0.0 0.3 17.5 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 20.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.0 1.3 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 92.1 11.0 73.4 0.1 0.4 0.2 0.3 0.0 0.1 0.0 0.0 0.0 CCDC3 DKFZp761F241 ENSG00000151468 "Coiled-coil domain containing 3" Q9BQI4 10 12896625-13099652 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 132.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 50.1;Excitatory neurons: 100.2;Inhibitory neurons: 41.3;Peritubular cells: 60.5;Smooth muscle cells: 119.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 10.4;HAP1: 19.1;HDLM-2: 32.4;hTERT-RPE1: 14.8;U-2 OS: 20.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 20.8" HPA062425 Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "HPA062425: AB_2684759" "unprognostic (2.26e-1)" "unprognostic (6.65e-3)" "unprognostic (1.70e-1)" "unprognostic (4.30e-3)" "unprognostic (1.72e-1)" "unprognostic (5.08e-2)" "unprognostic (3.11e-2)" "unprognostic (2.99e-2)" "unprognostic (5.56e-3)" "unprognostic (5.41e-2)" "unprognostic (4.25e-3)" "unprognostic (2.22e-2)" "prognostic unfavorable (1.38e-5)" "unprognostic (1.54e-2)" "unprognostic (1.49e-1)" "unprognostic (2.29e-1)" "unprognostic (3.88e-2)" 91.8 11.0 32.9 5.9 35.2 0.1 37.2 17.9 40.2 48.1 17.8 10.1 6.6 25.0 41.3 60.4 56.7 70.7 21.9 37.1 20.1 19.0 20.6 21.0 12.4 18.6 19.1 86.2 6.5 4.9 10.2 22.2 19.6 35.2 7.4 1.6 7.1 22.0 30.7 132.2 14.3 24.2 19.8 24.7 13.1 11.6 21.7 42.0 20.0 13.3 4.2 23.2 27.4 30.5 0.0 0.2 1.7 9.4 0.0 0.0 0.1 0.0 0.0 0.7 0.0 2.5 0.0 0.0 0.7 0.0 10.4 1.9 19.1 3.6 0.6 32.4 8.1 0.0 0.2 0.0 0.7 0.0 0.0 2.3 2.3 0.4 0.0 14.8 0.9 0.8 0.0 0.2 1.0 0.2 0.0 5.4 1.5 0.0 0.1 0.0 4.1 0.3 0.0 0.0 3.6 1.6 7.0 1.0 0.0 4.4 0.0 0.0 0.0 0.0 20.0 1.2 0.3 0.0 0.0 0.0 0.1 0.0 6.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 32.9 35.2 17.9 40.2 37.1 20.1 18.6 19.1 19.6 19.8 21.7 30.5 12.4 0.0 0.0 10.1 0.1 50.1 6.4 26.3 13.6 1.2 0.9 4.7 7.9 1.5 2.1 0.0 0.0 0.3 1.3 0.1 1.9 0.0 0.2 0.1 0.7 27.2 0.0 0.0 100.2 0.0 0.2 16.0 0.5 0.4 0.0 16.4 8.2 0.2 0.3 0.0 41.3 0.1 0.0 0.0 6.4 1.5 22.4 0.6 14.2 3.7 0.0 0.3 0.0 22.6 23.2 0.1 2.5 60.5 0.0 3.0 0.3 0.4 1.1 2.1 32.9 7.9 119.4 0.0 5.7 2.1 37.2 0.3 1.0 6.0 0.3 1.3 CCN3 "IGFBP9, NOV" ENSG00000136999 "Cellular communication network factor 3" P48745 8 119416446-119424434 "Plasma proteins, Predicted secreted proteins, Transporters" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 44 "adrenal gland: 1105.4" "Cell type enhanced" "Detected in some" "Adipocytes: 25.2;Endothelial cells: 2.7;Fibroblasts: 9.8;Smooth muscle cells: 4.6" "Cancer enriched" "Detected in all" 4 "melanoma: 62.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 116 "eosinophil: 64.8;neutrophil: 30.8" "Lineage enriched" "Detected in single" 157 "granulocytes: 64.8" "Cell line enhanced" "Detected in many" "BJ hTERT+: 125.0;hTERT-RPE1: 38.1;U-2197: 128.2" "Group enriched" "Detected in all" 6 "amygdala: 129.2;basal ganglia: 51.5;cerebral cortex: 99.5;hippocampal formation: 152.5;white matter: 85.0" "Region enriched" "Detected in all" 6 "spinal cord: 114.6" "HPA018449, HPA019684, CAB034423" Enhanced Enhanced Vesicles "Secreted to blood" NA NA 269000000 2800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB034423: AB_2151387, HPA018449: AB_1846189, HPA019684: AB_1846190" "unprognostic (5.04e-2)" "unprognostic (1.01e-1)" "unprognostic (7.36e-3)" "unprognostic (1.30e-3)" "unprognostic (9.35e-3)" "unprognostic (4.92e-1)" "unprognostic (8.10e-2)" "unprognostic (6.04e-2)" "unprognostic (1.79e-2)" "unprognostic (9.17e-2)" "unprognostic (1.67e-1)" "unprognostic (3.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.74e-3)" "unprognostic (1.51e-1)" "unprognostic (1.98e-1)" "unprognostic (2.72e-2)" 23.7 1105.4 7.6 3.6 11.5 1.7 8.1 6.7 12.2 11.2 5.9 6.9 3.9 8.6 6.3 5.5 9.0 6.3 18.1 16.2 9.7 6.9 1.1 6.8 2.2 5.6 6.5 3.1 6.8 9.4 21.8 0.6 4.9 22.8 7.0 1.2 2.7 20.0 4.7 13.8 4.4 8.4 8.7 1.5 4.9 3.6 6.3 1.0 25.3 7.2 1.9 4.4 8.0 6.2 0.1 3.1 1.7 0.0 11.1 2.9 0.1 16.9 125.0 14.9 8.6 0.0 0.3 0.0 12.9 21.2 11.6 10.5 0.6 0.0 5.1 0.0 0.3 0.0 9.1 0.0 0.4 0.0 0.0 0.6 0.1 5.7 0.6 38.1 0.4 0.0 0.0 0.0 0.8 0.7 0.0 0.1 0.2 1.2 24.9 0.1 0.0 0.0 15.8 0.1 3.9 0.1 6.3 0.1 24.2 0.0 0.0 0.0 0.0 10.6 15.8 128.2 3.5 0.0 0.0 0.0 16.7 5.4 12.5 0.0 0.3 64.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 30.8 0.0 0.0 0.0 0.0 0.1 7.6 11.5 6.7 12.2 16.2 9.7 5.6 6.5 4.9 8.7 6.3 6.2 25.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 CSDC2 PIPPin ENSG00000172346 "Cold shock domain containing C2" Q9Y534 22 41561010-41577741 "Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 143.8;heart muscle: 288.2;ovary: 133.6" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 75.0;Distal tubular cells: 19.6;Granulosa cells: 30.7;Muller glia cells: 51.7;Proximal tubular cells: 42.5;Sertoli cells: 72.3;Smooth muscle cells: 19.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HeLa: 12.4;U-2 OS: 41.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003073, HPA076549" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 9: U-2 OS - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm Cytosol "HPA003073: AB_1078578, HPA076549: AB_2686807" "unprognostic (9.42e-2)" "unprognostic (5.52e-2)" "unprognostic (3.66e-3)" "unprognostic (1.36e-1)" "unprognostic (2.06e-1)" "unprognostic (3.52e-1)" "unprognostic (3.93e-2)" "unprognostic (1.60e-1)" "unprognostic (2.70e-3)" "unprognostic (2.35e-2)" "unprognostic (1.93e-1)" "unprognostic (3.72e-1)" "prognostic favorable (6.42e-4)" "unprognostic (8.86e-3)" "unprognostic (6.08e-2)" "unprognostic (1.02e-1)" "unprognostic (9.09e-3)" 6.8 143.8 29.4 1.6 21.8 0.1 3.2 64.5 32.1 69.9 4.1 16.5 0.8 83.5 1.4 3.2 24.1 2.3 288.2 30.5 35.3 40.4 2.6 11.5 0.2 44.4 41.0 133.6 51.1 0.0 20.5 0.4 36.9 26.2 0.5 5.2 1.0 10.4 2.7 2.1 3.2 10.9 26.1 1.1 4.5 31.3 44.9 0.0 2.5 2.7 0.0 27.4 29.0 22.7 0.0 0.2 1.5 0.2 0.0 0.0 0.1 3.4 0.2 0.1 0.1 0.9 0.0 0.0 0.5 4.7 0.5 0.1 0.0 0.0 0.0 0.0 2.9 0.0 12.4 1.5 3.5 0.0 0.0 1.9 0.1 0.0 0.0 3.5 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.1 0.6 0.0 0.3 0.1 1.1 0.2 0.0 0.1 0.1 1.0 0.0 0.1 0.0 4.4 0.0 0.0 0.0 0.1 41.8 0.3 0.1 0.2 0.2 0.0 0.8 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 29.4 21.8 64.5 32.1 30.5 35.3 44.4 41.0 36.9 26.1 44.9 22.7 0.1 0.0 0.0 4.6 0.5 0.3 0.2 0.3 0.6 9.9 0.1 0.6 75.0 0.0 0.0 7.3 2.1 0.1 0.0 0.0 19.6 0.3 1.5 0.2 6.0 0.9 0.0 0.0 6.8 10.4 0.1 5.1 0.0 0.1 0.0 30.7 0.4 0.2 0.2 6.7 11.0 0.0 0.0 0.0 0.0 5.1 5.3 0.3 1.8 0.0 0.0 51.7 0.0 1.0 0.6 2.4 0.0 2.6 0.0 0.2 0.0 42.5 0.7 3.2 72.3 0.4 19.9 2.1 0.3 0.0 0.1 0.3 0.2 0.3 0.0 0.0 CSPG4 "CSPG4A, HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2" ENSG00000173546 "Chondroitin sulfate proteoglycan 4" Q6UVK1 15 75674322-75712848 "Predicted membrane proteins" "Angiogenesis, Differentiation, Tissue remodeling" "Developmental protein, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 55.4" "Group enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 57.3;Sertoli cells: 118.3;Smooth muscle cells: 47.1" "Cancer enhanced" "Detected in all" "melanoma: 74.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 64.7;SK-MEL-30: 146.1;U-138 MG: 92.1;WM-115: 138.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001933, HPA002951, CAB016189, HPA042785, HPA050008" Approved Enhanced "Nucleoplasm,Plasma membrane" NA NA 48000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Nucleoplasm "CAB016189: AB_784821, HPA001933: , HPA002951: AB_1854449, HPA042785: AB_10964270, HPA050008: AB_2680991" "unprognostic (5.21e-2)" "unprognostic (2.17e-3)" "unprognostic (3.55e-2)" "unprognostic (1.01e-2)" "unprognostic (3.56e-2)" "unprognostic (3.58e-1)" "unprognostic (1.09e-2)" "unprognostic (2.11e-2)" "unprognostic (1.07e-1)" "unprognostic (5.00e-2)" "unprognostic (1.63e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (7.60e-6)" "unprognostic (1.23e-2)" "unprognostic (2.04e-2)" "unprognostic (3.21e-2)" "prognostic unfavorable (4.93e-5)" 29.6 1.8 9.0 7.3 7.1 0.0 18.5 6.6 9.3 16.0 1.8 55.4 2.8 34.5 1.4 8.3 15.0 5.6 14.6 7.5 8.2 4.9 0.9 19.4 0.4 11.7 7.8 8.9 2.1 1.2 2.2 15.5 9.7 14.4 2.2 0.1 4.7 11.2 39.6 7.8 15.3 22.7 6.7 5.6 19.1 1.3 7.7 0.6 5.6 10.0 0.3 30.3 12.6 9.8 11.9 0.1 1.0 7.1 1.6 9.8 0.1 64.7 28.6 44.4 28.8 0.1 45.0 0.0 1.5 45.4 6.2 0.6 0.1 0.3 13.6 0.6 0.2 0.0 19.2 0.0 10.0 0.0 0.1 4.8 0.1 13.5 1.5 16.5 0.0 0.0 0.1 0.1 7.6 0.1 0.0 0.2 1.2 0.0 0.3 0.1 4.0 0.1 0.0 0.0 0.1 0.2 1.7 0.1 146.1 1.2 0.9 1.2 0.1 92.1 17.9 3.6 0.8 0.0 0.2 0.0 20.3 0.5 138.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.0 7.1 6.6 9.3 7.5 8.2 11.7 7.8 9.7 6.7 7.7 9.8 4.9 0.0 0.0 1.0 0.0 2.8 0.7 4.7 0.0 1.4 0.1 0.8 11.4 0.0 0.8 1.8 0.0 0.2 0.5 0.1 0.0 0.0 0.6 0.7 0.7 2.7 0.0 0.0 0.4 0.0 0.6 5.9 1.5 0.4 0.0 1.8 1.1 0.2 1.1 0.0 0.2 0.0 0.0 0.0 3.2 0.0 0.3 0.3 12.4 3.7 0.0 0.0 0.0 57.3 0.1 0.0 0.0 0.4 0.0 4.3 0.0 0.1 1.0 0.2 118.3 3.1 47.1 0.0 1.3 0.1 1.8 0.3 0.3 0.1 0.0 0.4 DNAJB5 Hsc40 ENSG00000137094 "DnaJ heat shock protein family (Hsp40) member B5" O75953 9 34989641-34998900 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 164.5;tongue: 218.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 42.9;Smooth muscle cells: 16.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "myeloid DC: 5.5;neutrophil: 5.2" "Group enriched" "Detected in many" 5 "dendritic cells: 5.5;granulocytes: 5.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023818, HPA050794" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm Cytosol "HPA023818: AB_1847793, HPA050794: AB_2681241" "unprognostic (1.41e-2)" "unprognostic (3.87e-1)" "unprognostic (2.53e-3)" "unprognostic (5.21e-2)" "unprognostic (1.86e-1)" "unprognostic (3.54e-2)" "unprognostic (7.31e-2)" "unprognostic (2.79e-1)" "unprognostic (2.57e-1)" "unprognostic (1.00e-2)" "unprognostic (1.31e-2)" "unprognostic (1.89e-1)" "unprognostic (1.17e-1)" "unprognostic (4.34e-3)" "unprognostic (2.44e-1)" "unprognostic (1.44e-1)" "unprognostic (1.00e-3)" 14.7 12.5 18.5 11.0 18.7 1.5 8.7 23.0 27.7 14.0 14.8 63.0 7.7 56.0 11.8 32.5 29.6 12.7 64.8 24.0 20.1 8.5 4.4 12.3 4.6 20.3 21.0 8.6 6.1 4.0 25.3 2.4 19.4 27.5 12.2 10.1 6.3 52.1 164.5 5.1 17.9 64.3 18.1 12.2 26.8 16.0 19.3 5.8 10.9 218.5 5.0 33.7 11.5 18.8 4.7 3.8 23.7 12.7 13.6 10.4 2.6 20.1 14.5 30.3 26.8 2.8 1.0 4.5 4.9 22.2 31.7 0.6 9.1 15.8 25.5 6.4 2.9 1.6 5.6 1.3 15.6 0.5 14.2 15.2 1.1 18.0 8.9 13.4 19.6 8.3 0.4 9.3 24.7 3.3 7.8 6.7 11.2 2.1 8.1 6.0 24.4 2.5 4.4 0.4 10.1 16.4 10.8 0.6 2.4 20.2 3.8 1.4 8.8 14.4 31.4 7.6 6.3 3.4 2.5 3.3 16.6 1.8 15.9 0.0 1.0 0.0 0.2 0.3 0.9 0.4 0.2 0.0 5.5 0.2 0.3 0.7 5.2 0.4 0.1 0.1 1.0 0.5 18.5 18.7 23.0 27.7 24.0 20.1 20.3 21.0 19.4 18.1 19.3 18.8 1.9 6.4 1.5 8.5 0.9 2.0 2.3 4.7 1.8 6.0 1.7 1.4 42.9 1.5 1.8 0.0 6.2 0.1 0.5 0.5 0.0 2.8 8.0 1.7 4.8 4.5 0.0 0.0 4.9 3.4 0.7 6.7 2.0 2.2 0.0 1.7 3.6 1.2 4.7 1.7 3.3 0.3 2.0 1.9 11.1 6.7 1.5 3.6 5.4 1.9 1.2 12.0 2.1 6.6 3.2 4.3 0.0 7.9 0.7 1.5 1.6 4.4 1.0 2.7 6.6 14.7 16.8 6.3 1.3 1.8 3.0 0.8 1.4 1.5 0.3 0.7 FBLIM1 "CAL, FBLP-1, migfilin" ENSG00000162458 "Filamin binding LIM protein 1" Q8WUP2 1 15756607-15786594 "Predicted intracellular proteins" "Cell adhesion, Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 207.3;Paneth cells: 153.6;Peritubular cells: 191.5;Proximal enterocytes: 145.9;Sertoli cells: 144.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 255.9;TIME: 420.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA025287, HPA072750" Approved Enhanced "Nucleoli fibrillar center,Cell Junctions,Focal adhesion sites" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions, Focal adhesion sites" "Nucleoli fibrillar center" "HPA025287: AB_1848443, HPA072750: AB_2686554" "unprognostic (4.10e-2)" "prognostic unfavorable (4.07e-4)" "unprognostic (2.26e-1)" "unprognostic (5.33e-2)" "unprognostic (2.46e-2)" "unprognostic (1.52e-1)" "unprognostic (9.33e-2)" "unprognostic (8.77e-3)" "prognostic unfavorable (6.15e-4)" "unprognostic (2.02e-1)" "unprognostic (1.67e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (8.64e-4)" "unprognostic (8.33e-2)" "unprognostic (3.01e-1)" "unprognostic (1.08e-1)" "unprognostic (8.21e-2)" 32.4 17.9 2.7 21.5 3.3 0.8 28.1 3.2 4.8 43.2 5.2 75.6 82.2 75.7 15.6 24.1 43.5 69.8 45.6 2.5 2.4 26.7 7.1 39.3 9.6 2.6 3.2 39.1 27.5 36.2 11.0 29.4 2.9 47.0 53.2 1.8 31.7 63.1 5.4 16.8 86.1 47.1 2.5 27.6 64.0 12.8 3.8 2.8 17.6 5.6 6.8 44.6 29.3 2.6 34.2 17.2 15.9 0.6 3.7 8.1 21.6 55.2 84.3 38.4 30.4 6.0 48.8 0.3 114.5 87.8 67.3 62.5 11.3 121.0 19.2 0.3 6.6 0.2 4.7 31.7 98.5 0.2 0.6 39.7 81.7 31.9 75.1 82.7 255.9 2.0 1.2 7.6 13.2 0.8 0.6 1.1 16.5 50.9 25.0 0.1 0.4 1.0 51.4 22.1 0.2 38.9 29.0 3.4 6.0 33.9 6.8 0.6 420.4 50.7 7.1 0.8 25.7 0.4 1.0 0.5 8.0 0.2 0.5 1.7 0.3 0.3 0.2 0.1 0.2 0.3 0.2 0.2 0.1 0.5 0.3 0.3 0.8 0.4 0.2 0.4 0.1 0.1 2.7 3.3 3.2 4.8 2.5 2.4 2.6 3.2 2.9 2.5 3.8 2.6 10.8 12.8 18.1 0.0 3.1 86.3 82.7 41.4 20.5 3.7 28.6 23.9 37.1 47.1 30.6 16.5 6.2 8.9 4.8 207.3 0.0 99.1 3.4 13.6 75.9 19.2 46.0 0.0 0.7 53.5 114.2 29.3 133.5 20.5 18.9 9.4 55.0 2.5 5.6 1.7 5.5 54.8 26.4 1.9 23.5 4.0 80.2 5.8 14.2 2.8 2.7 9.1 1.0 1.0 1.2 113.0 153.6 191.5 1.2 29.8 145.9 2.5 11.6 6.4 144.7 11.9 64.8 2.8 1.9 17.4 62.8 19.4 6.0 6.6 53.8 62.6 HSPB6 "FLJ32389, Hsp20, PPP1R91" ENSG00000004776 "Heat shock protein family B (small) member 6" O14558 19 35754566-35758079 "Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 2969.8;tongue: 1759.1" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 165.7;Fibroblasts: 125.2;Leydig cells: 271.8;Peritubular cells: 220.4;Smooth muscle cells: 102.6;Theca cells: 311.0" "Cancer enhanced" "Detected in all" "stomach cancer: 93.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1774.3;ASC TERT1: 742.0;HHSteC: 599.9;HSkMC: 700.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001974, HPA044153, HPA054811" Enhanced Supported "Nucleoli,Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 310000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "Nucleoli, Golgi apparatus" "CAB001974: , HPA044153: AB_2678836, HPA054811: AB_2682610" "unprognostic (3.19e-2)" "unprognostic (8.07e-2)" "unprognostic (1.41e-2)" "unprognostic (1.01e-1)" "unprognostic (5.21e-3)" "unprognostic (7.02e-2)" "unprognostic (9.67e-2)" "unprognostic (7.57e-2)" "unprognostic (1.18e-1)" "unprognostic (7.23e-2)" "unprognostic (1.20e-1)" "unprognostic (7.02e-2)" "prognostic unfavorable (1.93e-5)" "unprognostic (3.32e-2)" "unprognostic (6.65e-2)" "unprognostic (5.61e-2)" "prognostic unfavorable (1.43e-6)" 650.0 414.0 37.3 45.4 40.6 0.4 394.9 32.5 49.2 581.9 26.1 699.9 28.1 565.1 101.6 112.3 495.1 97.9 1463.9 30.0 43.6 69.0 42.3 126.6 5.7 76.7 48.5 455.2 50.5 4.2 17.5 40.2 73.7 271.2 44.0 21.1 115.9 194.7 2969.8 39.1 180.0 278.2 50.8 15.7 362.1 60.6 53.8 6.2 99.5 1759.1 2.7 537.3 290.6 49.3 0.6 0.7 2.1 2.5 1774.3 742.0 1.2 83.0 1.3 4.9 9.3 1.1 0.4 0.7 0.6 252.4 0.0 0.2 0.4 0.7 3.9 0.9 0.5 0.4 1.3 0.5 599.9 0.2 0.9 700.3 0.0 19.1 0.9 2.2 5.4 0.3 0.5 1.0 0.2 0.3 0.4 1.9 1.2 2.3 0.6 1.5 0.5 0.7 0.0 0.1 0.8 0.7 0.1 0.2 0.7 0.3 0.3 0.5 0.1 153.2 0.9 17.3 0.6 1.0 2.8 0.3 20.5 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.3 40.6 32.5 49.2 30.0 43.6 76.7 48.5 73.7 50.8 53.8 49.3 11.1 3.2 0.6 1.6 0.1 1.8 0.4 0.0 3.4 7.8 0.5 0.5 29.7 0.0 0.0 0.0 0.0 2.5 0.1 0.1 0.0 0.1 27.0 4.9 165.7 3.6 0.0 5.2 0.2 0.0 2.5 125.2 4.1 3.5 0.0 3.6 17.5 0.3 5.0 0.0 0.5 0.0 0.0 0.3 3.6 18.9 271.8 2.7 1.8 0.0 0.6 44.5 0.0 0.0 0.1 0.2 0.0 220.4 0.1 0.4 0.0 0.4 0.0 2.8 26.3 38.0 102.6 2.3 1.4 1.9 2.0 4.8 1.8 311.0 0.0 0.5 HTR1B "5-HT1B, 5-HT1DB, HTR1D2, S12" ENSG00000135312 "5-hydroxytryptamine receptor 1B" P28222 6 77460924-77463491 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 9.6;placenta: 6.7;stomach 1: 5.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "pancreatic cancer: 0.7;stomach cancer: 0.8;testis cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "HUVEC TERT2: 79.4;TIME: 35.1" "Region enriched" "Detected in all" 4 "basal ganglia: 38.6" "Region enhanced" "Detected in many" "basal ganglia: 11.7" HPA028808 Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Plasma membrane" "Endoplasmic reticulum" "HPA028808: AB_2672782" "unprognostic (3.86e-2)" "unprognostic (3.56e-1)" "unprognostic (7.68e-2)" "unprognostic (2.58e-1)" "unprognostic (1.88e-1)" "unprognostic (1.18e-2)" "unprognostic (2.67e-1)" "unprognostic (2.11e-1)" "unprognostic (8.96e-2)" "unprognostic (4.03e-1)" "unprognostic (1.77e-2)" "unprognostic (1.24e-1)" "unprognostic (1.10e-3)" "unprognostic (3.08e-2)" "unprognostic (2.81e-2)" "unprognostic (1.34e-1)" "unprognostic (1.02e-1)" 0.8 0.6 2.1 0.4 6.0 0.0 0.2 0.0 3.8 0.8 0.0 0.1 0.1 0.5 0.0 0.0 0.5 0.5 0.0 1.2 2.1 0.5 0.0 0.4 0.0 0.6 4.3 0.3 0.1 0.0 0.2 6.7 1.2 0.2 0.1 0.3 0.2 0.5 0.1 0.2 0.1 0.1 0.1 0.0 5.0 0.5 9.6 0.0 0.2 0.3 0.0 1.3 0.5 1.4 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.4 3.5 1.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.4 0.2 0.6 2.2 1.4 79.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 35.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 6.0 0.0 3.8 1.2 2.1 0.6 4.3 1.2 0.1 9.6 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ITIH3 H3P ENSG00000162267 "Inter-alpha-trypsin inhibitor heavy chain 3" Q06033 3 52794768-52809009 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 97 "liver: 792.7" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 1183.8" "Cancer enriched" "Detected in some" 247 "liver cancer: 273.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "Hep G2: 17.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA017373 Approved "Secreted to blood" NA NA 9100000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA017373: AB_1851954" "unprognostic (2.07e-2)" "unprognostic (5.79e-2)" "unprognostic (1.89e-1)" "unprognostic (3.30e-4)" "unprognostic (4.28e-2)" "unprognostic (3.26e-2)" "unprognostic (5.97e-2)" "unprognostic (6.07e-2)" "unprognostic (1.49e-1)" "unprognostic (7.05e-2)" "unprognostic (1.04e-1)" "unprognostic (3.19e-1)" "prognostic unfavorable (4.49e-8)" "unprognostic (2.09e-4)" "unprognostic (1.70e-1)" "unprognostic (2.55e-2)" "unprognostic (9.31e-2)" 5.0 0.7 0.5 0.9 0.7 0.0 2.1 0.5 0.8 5.3 0.4 1.1 0.3 3.5 1.7 1.3 3.4 1.2 0.7 0.5 0.4 0.7 792.7 3.0 2.5 0.4 0.4 2.8 0.3 0.1 0.3 1.7 0.5 1.1 1.0 0.1 0.4 2.4 0.6 1.3 1.2 1.2 0.4 8.1 1.2 3.5 0.4 0.2 1.2 0.4 1.7 1.4 2.3 0.5 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.5 0.8 0.5 0.4 0.4 0.4 0.5 0.4 0.4 0.5 0.1 0.0 0.0 0.0 21.6 0.1 0.0 0.0 0.0 0.5 0.1 1.4 0.8 78.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.2 0.1 0.1 3.5 0.0 90.9 0.0 0.0 0.1 2.1 0.0 0.0 0.0 12.3 66.4 1183.8 0.0 0.0 0.0 0.0 0.0 85.1 0.3 132.0 1.2 0.1 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 9.1 0.4 0.3 0.0 0.1 0.3 3.6 19.2 0.0 0.1 KLHL30 FLJ43374 ENSG00000168427 "Kelch like family member 30" Q0D2K2 2 238138668-238152947 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "skeletal muscle: 149.1" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 13.5;Skeletal myocytes: 9.8;Smooth muscle cells: 3.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.1;CAPAN-2: 1.6;EFO-21: 1.5;REH: 1.4;RH-30: 4.5;THP-1: 2.3" "Region enriched" "Detected in single" 35 "olfactory bulb: 9.4" "Not detected" "Not detected" HPA062095 Approved "Centriolar satellite" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "Centriolar satellite" "HPA062095: AB_2684680" "unprognostic (3.42e-2)" "unprognostic (1.04e-1)" "unprognostic (2.07e-4)" "unprognostic (6.02e-5)" "unprognostic (1.29e-1)" "unprognostic (1.22e-2)" "unprognostic (1.31e-1)" "unprognostic (4.54e-3)" "unprognostic (1.07e-1)" "unprognostic (1.63e-1)" "unprognostic (5.57e-3)" "unprognostic (2.24e-1)" "unprognostic (1.93e-1)" "unprognostic (8.17e-4)" "unprognostic (2.75e-2)" "unprognostic (2.30e-1)" "unprognostic (2.06e-1)" 3.8 0.1 0.2 0.1 0.2 0.0 1.4 0.5 0.2 2.2 0.2 1.0 0.2 1.2 0.0 1.0 1.3 0.5 14.3 0.1 0.4 1.0 0.1 0.9 0.0 0.9 0.8 0.4 0.1 0.0 0.1 0.3 0.3 1.0 0.1 0.1 1.0 0.8 149.1 0.8 0.7 0.7 0.1 0.2 0.5 0.1 0.2 0.0 0.6 15.2 0.0 1.6 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.1 0.1 0.0 0.0 1.4 4.5 0.7 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 2.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.2 0.1 0.4 0.9 0.8 0.3 0.1 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.4 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 9.8 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LDB3 "CMD1C, KIAA0613, PDLIM6, ZASP" ENSG00000122367 "LIM domain binding 3" O75112 10 86668507-86736072 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cardiomyopathy, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 26 "heart muscle: 1423.0;skeletal muscle: 2945.6;tongue: 1809.4" "Cell type enriched" "Detected in many" 7 "Cardiomyocytes: 1825.0" "Group enriched" "Detected in some" 4 "head and neck cancer: 1.7;melanoma: 2.5;prostate cancer: 3.6;stomach cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 3.0;hTERT-RPE1: 3.3;SCLC-21H: 4.9;SK-MEL-30: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048955 Enhanced Supported "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA 750000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 54: Cardiomyocytes - Muscle contraction" "Focal adhesion sites, Cytosol" Nucleoplasm "HPA048955: AB_2680568" "unprognostic (1.60e-1)" "unprognostic (9.01e-2)" "unprognostic (4.87e-2)" "unprognostic (6.92e-2)" "unprognostic (5.55e-2)" "unprognostic (1.50e-2)" "unprognostic (2.57e-2)" "unprognostic (1.36e-1)" "unprognostic (2.79e-2)" "unprognostic (7.61e-2)" "unprognostic (2.54e-3)" "unprognostic (3.55e-2)" "unprognostic (4.72e-4)" "unprognostic (3.07e-2)" "unprognostic (1.60e-1)" "unprognostic (1.62e-2)" "unprognostic (3.16e-1)" 11.1 1.4 12.8 2.8 39.6 0.4 6.5 29.8 29.0 10.1 0.1 36.2 2.4 15.1 4.9 54.5 17.3 3.1 1423.0 14.7 23.3 2.0 0.8 5.1 0.5 55.5 36.9 6.4 1.3 0.5 2.4 2.7 46.2 38.1 5.3 0.7 20.8 25.2 2945.6 4.8 8.8 23.7 26.4 0.6 9.0 4.7 38.4 0.7 5.2 1809.4 0.3 7.0 10.3 78.4 0.1 0.1 0.2 1.7 0.2 0.0 0.2 0.2 0.1 0.0 0.1 0.1 0.2 0.1 0.3 0.0 0.3 0.2 0.0 0.0 0.0 0.5 0.4 0.4 0.7 0.0 0.0 0.0 0.9 3.0 0.2 0.0 0.0 3.3 0.0 0.3 0.1 1.0 0.0 0.8 0.2 0.1 0.2 0.2 0.2 0.0 1.1 0.0 0.0 0.6 4.9 0.9 0.2 0.1 2.4 0.7 0.2 0.1 0.0 0.1 0.2 0.2 0.0 0.1 0.3 0.2 0.4 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.8 39.6 29.8 29.0 14.7 23.3 55.5 36.9 46.2 26.4 38.4 78.4 1.5 0.0 0.0 1.0 0.0 1.0 0.5 0.2 0.0 1.5 0.2 0.3 1825.0 0.0 0.2 1.8 0.0 0.1 0.0 0.0 0.0 0.0 23.4 0.1 0.4 15.5 0.0 0.0 4.5 1.1 0.0 31.5 0.0 0.2 0.0 0.9 0.0 0.0 0.1 0.0 2.6 0.0 4.1 0.0 1.2 19.6 11.1 0.5 1.8 1.9 0.0 0.7 0.0 1.5 245.1 0.1 0.0 6.8 0.0 0.3 0.0 0.1 0.1 4.1 39.5 48.0 54.9 1.0 1.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 MARK1 "MARK, PAR-1C" ENSG00000116141 "Microtubule affinity regulating kinase 1" Q9P0L2 1 220528136-220664461 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 73.8;Excitatory neurons: 171.3;Inhibitory neurons: 170.1;Oligodendrocyte precursor cells: 167.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 11.3;RT4: 33.7;SuSa: 12.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007421, HPA008061" Uncertain NA NA "Cluster 77: Retina - Visual perception" "Cluster 15: RT4 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA007421: AB_1079311, HPA008061: AB_1079310" "unprognostic (1.51e-1)" "unprognostic (6.27e-2)" "unprognostic (6.72e-2)" "unprognostic (3.63e-2)" "unprognostic (2.23e-1)" "unprognostic (1.01e-1)" "unprognostic (1.54e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (2.63e-4)" "unprognostic (4.59e-2)" "prognostic favorable (2.23e-5)" "unprognostic (6.62e-2)" "unprognostic (4.27e-2)" "unprognostic (9.56e-3)" "unprognostic (3.35e-2)" "unprognostic (1.72e-1)" "unprognostic (3.74e-2)" 6.3 1.8 6.9 1.4 7.1 0.0 4.9 6.4 10.0 4.6 8.4 5.4 0.4 4.2 9.7 4.8 3.3 1.7 8.0 7.4 6.7 2.3 0.3 3.1 0.5 6.4 6.8 1.7 0.9 2.4 6.9 1.1 7.4 3.0 1.2 9.3 3.7 4.0 2.2 2.5 2.5 3.9 5.7 1.3 2.8 6.9 6.5 1.4 4.3 3.5 1.9 5.3 5.1 6.4 0.4 0.0 5.4 1.1 0.0 0.0 1.8 1.6 2.2 1.8 2.5 0.0 0.0 0.0 0.0 0.0 2.5 2.5 11.3 6.0 1.0 0.0 8.4 0.0 2.3 0.0 0.0 0.7 0.8 0.9 4.7 0.0 3.0 0.8 0.2 2.7 0.0 0.0 0.0 0.0 0.0 0.0 8.1 5.5 1.8 0.0 7.4 0.0 0.0 33.7 6.4 6.2 0.3 0.3 0.5 12.2 0.5 0.0 0.0 0.0 2.4 4.0 7.1 0.0 0.0 0.0 1.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 7.1 6.4 10.0 7.4 6.7 6.4 6.8 7.4 5.7 6.5 6.4 3.2 0.0 0.5 73.8 0.5 3.4 2.6 10.0 13.1 28.6 1.6 3.8 21.9 0.0 4.7 3.7 31.3 2.1 0.0 0.7 0.0 1.6 7.3 19.3 6.4 3.4 9.0 0.0 171.3 0.0 2.3 6.3 2.6 35.5 0.0 13.6 3.3 0.0 0.3 10.1 170.1 0.4 4.1 0.3 1.5 3.6 2.1 0.2 0.0 15.0 0.0 12.3 0.0 167.9 45.9 0.1 0.0 6.4 0.6 4.8 1.5 0.2 4.1 11.9 0.0 6.9 17.5 17.4 5.1 13.1 3.3 1.0 0.4 1.1 0.9 4.8 MUSTN1 Mustang ENSG00000272573 "Musculoskeletal, embryonic nuclear protein 1" Q8IVN3 3 52833114-52835019 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "skeletal muscle: 1689.2" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 1.3;Skeletal myocytes: 1.0;Smooth muscle cells: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 4.7;Hep G2: 8.0;HSkMC: 4.8;RH-30: 4.4" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 80: Striated muscle - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (2.79e-2)" "unprognostic (3.73e-2)" "unprognostic (4.11e-1)" "unprognostic (2.60e-2)" "unprognostic (2.34e-2)" "unprognostic (6.21e-3)" "unprognostic (2.78e-1)" "unprognostic (1.13e-2)" "unprognostic (1.66e-2)" "unprognostic (1.04e-1)" "unprognostic (1.65e-3)" "unprognostic (6.00e-2)" "unprognostic (1.79e-1)" "unprognostic (8.11e-2)" "unprognostic (1.88e-2)" 86.1 10.1 107.0 9.3 118.7 6.5 46.4 106.9 177.9 89.1 105.7 27.2 8.4 44.6 49.0 44.9 52.1 42.5 142.5 104.2 105.8 17.5 12.5 31.0 5.4 107.2 107.4 37.6 6.6 1.6 12.1 4.5 110.3 43.8 21.2 0.8 26.3 59.3 1689.2 28.7 26.7 30.6 99.9 10.9 22.1 4.3 118.5 5.7 31.1 305.6 3.9 54.5 65.7 105.1 0.0 0.0 4.7 0.0 0.5 2.1 1.9 0.0 0.5 0.2 0.5 0.0 0.5 0.0 0.0 1.4 0.2 0.4 0.6 1.3 0.4 0.1 0.5 0.0 1.4 8.0 0.3 1.0 0.4 4.8 1.0 0.6 0.7 0.9 1.2 0.9 0.0 0.0 0.3 0.1 0.4 1.6 0.1 0.6 1.0 0.3 4.4 0.0 0.9 0.0 0.2 0.3 0.3 0.4 0.4 2.0 0.1 2.6 0.0 0.6 0.2 1.0 0.2 0.0 0.0 0.3 0.5 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 107.0 118.7 106.9 177.9 104.2 105.8 107.2 107.4 110.3 99.9 118.5 105.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MYL6 "ESMLC, MLC1SM, MLC3NM" ENSG00000092841 "Myosin light chain 6" P60660 12 56158346-56163496 "Plasma proteins, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046859, HPA063034" Approved NA NA 60000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA046859: AB_2679842, HPA063034: AB_2684927" "unprognostic (1.10e-1)" "unprognostic (4.99e-2)" "unprognostic (1.89e-1)" "unprognostic (3.86e-2)" "unprognostic (1.43e-1)" "unprognostic (1.89e-1)" "unprognostic (3.73e-2)" "unprognostic (3.53e-1)" "unprognostic (2.00e-1)" "unprognostic (3.51e-3)" "unprognostic (4.11e-2)" "unprognostic (2.04e-1)" "unprognostic (2.86e-2)" "unprognostic (8.33e-3)" "unprognostic (1.71e-1)" "unprognostic (7.90e-2)" "unprognostic (2.01e-1)" 2247.0 1427.5 830.7 1207.0 830.7 1756.5 1977.9 864.2 962.6 1767.3 901.0 5900.2 1027.9 2971.8 1635.0 1777.8 2197.9 905.8 1153.9 809.9 863.8 1915.8 1172.0 1946.7 882.9 900.5 874.9 1155.2 1032.8 1466.7 747.7 1441.7 869.2 2037.5 2360.3 927.1 1167.6 2912.2 411.1 1090.1 1867.5 4209.9 858.5 1547.8 2128.0 494.6 899.3 1151.3 1316.7 578.7 1404.7 3041.7 1685.0 869.9 1924.9 1739.1 3199.3 958.8 2063.5 2065.5 1755.8 4056.4 4162.8 5469.7 3191.3 2738.5 1720.0 735.0 2274.3 5778.4 1417.7 1222.8 1995.9 2846.0 3556.8 1423.1 666.5 1311.5 2481.7 1536.9 1512.2 913.8 2304.1 2389.9 2013.5 3242.3 1263.1 4706.8 4854.4 867.2 708.1 2121.5 4585.6 2052.1 1291.6 1402.8 1629.5 1071.6 1746.1 1027.3 1265.3 932.9 5125.1 2361.7 1169.2 862.9 4456.0 1380.0 760.4 2312.4 2148.7 2383.0 5212.3 1486.3 1011.6 2077.3 2746.8 635.3 1150.3 867.7 1953.3 1168.9 1578.1 11449.4 4509.8 13302.4 3191.2 5016.0 2404.9 2844.7 2828.6 2994.0 4747.3 2558.5 2020.7 2528.3 8440.7 2233.9 6531.2 5167.0 4209.8 14776.8 830.7 830.7 864.2 962.6 809.9 863.8 900.5 874.9 869.2 858.5 899.3 869.9 2044.5 1733.9 1161.8 16.0 704.4 2114.0 2470.4 2988.3 746.1 278.4 896.3 1394.8 672.8 946.5 2016.5 1475.0 316.9 1704.4 1144.5 2568.2 2406.5 4126.7 292.4 1134.2 1714.2 1628.1 1017.3 857.4 15.6 4820.4 2604.5 1264.0 871.6 1676.6 994.3 1307.8 1328.6 887.8 3370.3 80.8 19.8 1572.3 1845.3 1148.3 2472.8 910.7 1064.0 1872.2 1469.2 39.4 4426.3 820.8 1195.7 17.6 31.3 6222.1 2715.8 2775.1 892.8 1762.1 3007.9 2956.9 1870.9 763.7 1735.5 685.8 3305.2 76.2 115.0 1139.6 2066.1 1929.9 1191.9 1039.1 1406.1 2558.6 MYOCD MYCD ENSG00000141052 Myocardin Q8IZQ8 17 12665890-12768949 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.2" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 47.3;Endometrial stromal cells: 48.5;Peritubular cells: 100.8;Sertoli cells: 26.3;Smooth muscle cells: 32.9" "Cancer enhanced" "Detected in some" "stomach cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 6.5;BJ hTERT+: 6.4;HBF TERT88: 10.4;hTEC/SVTERT24-B: 11.7;REH: 8.4;SuSa: 12.8" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 4.1" "CAB046485, HPA071528, HPA072582" Approved Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "CAB046485: AB_10600720, HPA071528: , HPA072582: " "unprognostic (2.82e-1)" "unprognostic (1.69e-1)" "unprognostic (2.36e-2)" "unprognostic (1.90e-1)" "unprognostic (3.79e-2)" "unprognostic (5.33e-2)" "unprognostic (2.15e-4)" "unprognostic (2.71e-2)" "unprognostic (1.61e-2)" "unprognostic (2.31e-1)" "unprognostic (1.76e-1)" "unprognostic (4.83e-2)" "unprognostic (1.01e-4)" "unprognostic (2.88e-2)" "unprognostic (1.07e-1)" "unprognostic (5.45e-2)" "unprognostic (1.91e-2)" 3.2 1.0 0.4 4.3 0.7 0.0 1.2 0.3 0.8 9.4 1.6 24.2 2.6 13.0 2.4 13.1 8.5 4.6 14.2 0.4 0.4 0.7 0.2 2.7 0.1 0.5 0.5 4.4 0.3 0.1 0.2 3.4 0.8 8.8 4.9 0.0 0.2 20.7 0.5 1.3 5.1 15.8 0.5 0.6 6.1 2.1 0.8 0.1 0.7 0.8 0.1 17.2 4.4 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.5 6.4 2.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.3 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 8.4 1.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 12.8 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.3 0.8 0.4 0.4 0.5 0.5 0.8 0.5 0.8 0.4 0.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 47.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 2.0 48.5 1.2 7.8 0.0 1.2 0.2 0.1 3.6 0.0 1.0 0.0 8.4 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 1.0 0.5 0.6 0.2 0.0 9.4 0.0 0.0 0.0 1.0 0.3 0.0 0.0 100.8 0.0 0.1 0.0 0.1 0.0 0.0 26.3 0.2 32.9 0.3 0.8 0.1 0.9 0.5 0.4 6.0 0.0 0.1 NOTCH3 "CADASIL, CASIL" ENSG00000074181 "Notch receptor 3" Q9UM47 19 15159038-15200995 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 414.2;Skeletal myocytes: 131.6;Smooth muscle cells: 317.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 66.3;MCF7: 66.9;RT4: 41.2;U-87 MG: 45.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005393, HPA044392" Approved Supported "Nucleoplasm,Actin filaments,Cytosol" NA NA 46000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "Actin filaments" "CAB005393: AB_2151246, HPA044392: AB_2678926" "unprognostic (4.97e-2)" "unprognostic (3.89e-2)" "unprognostic (7.06e-3)" "prognostic unfavorable (5.92e-4)" "unprognostic (9.20e-2)" "unprognostic (1.73e-2)" "unprognostic (2.72e-1)" "unprognostic (9.04e-2)" "unprognostic (3.90e-3)" "unprognostic (1.23e-1)" "unprognostic (1.19e-1)" "unprognostic (3.13e-1)" "prognostic unfavorable (2.53e-7)" "unprognostic (3.35e-2)" "unprognostic (8.34e-3)" "unprognostic (4.40e-2)" "unprognostic (2.00e-3)" 85.7 5.3 14.8 10.4 12.4 0.2 50.5 11.0 21.3 49.4 7.1 14.8 5.5 39.9 16.9 74.3 35.8 23.5 43.6 9.5 11.3 26.0 3.2 38.3 9.2 12.0 15.2 18.9 10.7 12.6 10.3 59.8 14.3 22.0 4.2 0.5 24.4 16.5 29.7 82.1 14.3 16.9 8.2 15.0 11.6 3.8 15.8 34.1 32.3 25.1 10.4 26.3 55.1 10.0 13.0 8.1 66.3 30.3 9.2 7.3 29.8 10.2 0.4 0.4 0.3 15.6 13.4 0.4 7.7 18.9 0.1 15.1 12.1 0.2 0.6 0.1 3.1 0.4 12.4 3.5 4.5 0.0 1.2 8.4 7.3 15.5 1.6 0.6 0.8 4.6 0.5 0.6 1.2 66.9 15.9 0.1 38.8 11.2 0.0 0.1 3.7 0.3 0.0 41.2 1.9 21.4 0.1 37.8 0.0 19.6 40.3 0.1 0.0 1.9 21.0 0.3 0.1 0.1 0.7 0.0 45.7 0.4 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 14.8 12.4 11.0 21.3 9.5 11.3 12.0 15.2 14.3 8.2 15.8 10.0 39.6 9.6 1.5 5.9 0.4 24.1 7.8 17.8 4.6 0.4 41.5 30.7 60.7 0.0 28.5 16.5 0.0 20.2 1.0 0.0 5.9 14.8 0.5 4.8 13.5 32.0 0.0 0.0 0.6 0.0 3.9 24.2 2.0 11.8 0.0 5.9 4.2 0.0 2.8 0.0 0.3 0.3 6.1 10.4 12.3 0.1 9.0 4.1 17.8 13.1 0.7 0.8 0.0 0.0 0.2 0.9 0.1 11.7 0.0 13.0 0.1 0.0 4.2 0.8 414.2 131.6 317.0 0.9 1.2 72.1 72.2 31.5 2.0 1.2 0.2 36.0 PDLIM3 ALP ENSG00000154553 "PDZ and LIM domain 3" Q53GG5 4 185500660-185535507 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "skeletal muscle: 4781.7;tongue: 1519.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 228.9;Ductal cells: 332.7;Melanocytes: 124.5;Peritubular cells: 196.0;Skeletal myocytes: 428.3;Smooth muscle cells: 131.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 115.6;RH-30: 26.9;U-266/70: 111.2;U-266/84: 34.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004749 Enhanced Supported Cytosol NA NA 240000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 37: Myocytes - Muscle contraction" Cytosol "HPA004749: AB_1855150" "unprognostic (2.75e-1)" "unprognostic (3.85e-2)" "unprognostic (3.20e-2)" "unprognostic (2.49e-1)" "unprognostic (1.08e-2)" "unprognostic (1.11e-2)" "prognostic unfavorable (7.22e-4)" "unprognostic (3.15e-2)" "unprognostic (3.64e-1)" "unprognostic (1.62e-1)" "unprognostic (9.46e-2)" "unprognostic (3.77e-1)" "prognostic unfavorable (4.97e-7)" "unprognostic (1.64e-3)" "unprognostic (7.77e-2)" "prognostic unfavorable (2.13e-6)" "unprognostic (2.78e-3)" 36.3 11.5 12.7 25.7 13.3 0.0 34.5 16.8 14.8 22.7 10.9 201.2 20.8 235.3 59.1 216.2 97.5 40.1 314.0 12.0 15.7 13.9 7.7 55.2 10.7 19.9 14.2 38.1 18.7 0.8 20.7 18.8 13.8 87.0 32.5 11.2 56.3 148.1 4781.7 12.1 69.0 127.6 17.9 24.5 95.8 8.2 14.6 4.1 32.7 1519.6 26.2 141.1 40.8 14.2 0.0 0.0 0.9 0.0 0.3 0.0 0.8 0.0 0.0 0.3 1.0 1.2 0.4 0.0 0.0 0.0 6.0 0.0 0.0 0.2 0.0 0.0 15.1 0.0 0.8 4.7 13.5 0.0 0.0 8.7 0.0 2.6 0.0 12.3 9.1 0.0 0.0 0.0 115.6 0.0 0.0 0.1 2.4 0.0 1.0 0.0 26.9 0.3 0.0 0.0 17.6 13.3 0.0 0.0 7.3 2.8 0.6 0.0 7.9 0.0 7.6 0.1 7.1 111.2 34.8 0.0 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 13.3 16.8 14.8 12.0 15.7 19.9 14.2 13.8 17.9 14.6 14.2 22.4 9.6 6.0 37.2 2.6 8.9 11.4 0.7 12.5 12.1 72.8 105.7 228.9 5.7 2.2 0.0 12.5 2.5 0.6 0.2 0.0 332.7 0.4 1.4 0.8 39.0 3.5 0.0 2.5 16.7 2.7 82.9 1.1 1.1 0.0 1.3 67.5 0.9 1.6 5.0 0.5 0.5 2.0 1.8 11.7 2.6 19.6 2.3 124.5 1.0 3.2 36.4 0.0 6.6 2.6 31.2 0.0 196.0 7.3 12.2 0.0 0.2 3.2 44.3 105.2 428.3 131.4 4.0 12.6 2.4 7.1 12.2 2.5 2.4 0.3 3.9 PPP1R14A "CPI-17, PPP1INL" ENSG00000167641 "Protein phosphatase 1 regulatory inhibitor subunit 14A" Q96A00 19 38251237-38256532 "Plasma proteins, Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 492.0;intestine: 450.3" "Cell type enhanced" "Detected in many" "Adipocytes: 332.5;Granulosa cells: 435.0;Leydig cells: 341.1;Peritubular cells: 656.0;Sertoli cells: 979.5;Smooth muscle cells: 465.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory B-cell: 299.4;naive B-cell: 283.9;plasmacytoid DC: 246.9" "Group enriched" "Detected in many" 24 "B-cells: 299.4;dendritic cells: 246.9" "Group enriched" "Detected in some" 4 "A549: 164.1;EFO-21: 112.2;K-562: 64.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005044, CAB009803, HPA042097, HPA054534" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA 880000 "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "Nuclear bodies" "CAB005044: AB_562091, CAB009803: AB_2168720, HPA042097: AB_2677846, HPA054534: AB_2682518" "unprognostic (5.40e-2)" "unprognostic (4.00e-3)" "unprognostic (4.02e-2)" "unprognostic (2.53e-1)" "unprognostic (1.74e-1)" "unprognostic (8.92e-3)" "unprognostic (2.18e-3)" "unprognostic (1.30e-1)" "unprognostic (2.28e-2)" "unprognostic (1.96e-1)" "unprognostic (1.27e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (1.25e-5)" "prognostic unfavorable (7.12e-4)" "unprognostic (4.13e-1)" "unprognostic (5.81e-2)" "unprognostic (2.22e-2)" 134.0 144.2 175.2 22.1 347.5 2.9 111.9 321.5 226.5 149.7 63.2 450.3 18.6 273.5 5.2 47.6 153.7 14.8 94.6 175.2 219.6 53.3 17.9 163.1 2.6 402.3 322.9 125.1 31.1 2.8 12.6 34.1 336.3 142.0 12.6 0.3 19.0 86.1 27.5 28.6 82.1 57.2 222.0 101.2 140.3 77.6 365.3 1.7 25.8 12.3 1.4 301.6 106.1 492.0 0.0 164.1 0.4 0.0 1.0 0.0 6.1 10.8 0.0 0.1 0.0 12.8 0.2 0.0 112.2 1.0 0.0 0.5 13.6 0.2 0.0 1.4 0.0 25.5 0.0 0.0 4.6 0.0 0.0 0.3 0.0 1.4 0.0 0.0 0.1 0.0 64.5 0.3 0.0 0.8 0.0 0.3 4.9 0.0 0.0 0.2 2.4 0.4 0.4 0.0 3.5 0.2 0.0 0.0 0.1 9.2 0.0 0.4 0.4 0.0 0.8 0.4 0.0 0.4 0.0 0.5 0.2 0.0 0.1 11.3 0.6 1.2 0.1 0.7 0.2 299.4 0.2 0.4 44.3 283.9 0.6 0.1 1.7 8.7 0.2 246.9 0.2 21.6 175.2 347.5 321.5 226.5 175.2 219.6 402.3 322.9 336.3 222.0 365.3 492.0 332.5 0.0 1.1 1.3 29.9 9.6 3.0 1.2 3.4 0.4 8.8 209.8 19.6 2.8 0.7 0.0 0.0 48.3 48.7 32.7 0.0 0.7 14.1 15.4 239.5 108.5 1.8 34.7 0.5 10.9 7.4 66.8 2.0 10.8 3.8 435.0 224.5 2.3 9.5 0.0 0.6 0.4 0.0 5.6 24.6 42.1 341.1 41.4 8.8 14.0 66.1 0.5 4.1 3.5 155.6 2.2 2.6 656.0 4.8 2.4 3.8 0.3 0.0 1.6 979.5 8.7 465.2 9.9 46.2 0.6 8.0 26.4 3.7 66.0 0.4 1.2 RAMP1 ENSG00000132329 "Receptor activity modifying protein 1" O60894 2 237858893-237912106 "FDA approved drug targets, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 706.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 190.0;Endometrial stromal cells: 546.4;Exocrine glandular cells: 278.2;monocytes: 433.5" "Cancer enhanced" "Detected in all" "prostate cancer: 152.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 18 "NK-cell: 70.1" "Lineage enriched" "Detected in many" 18 "NK-cells: 70.1" "Cell line enhanced" "Detected in many" "CAPAN-2: 47.4;HDLM-2: 146.0;PC-3: 173.8;SH-SY5Y: 201.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057814 Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Nuclear membrane" "HPA057814: AB_2683536" "unprognostic (1.13e-2)" "unprognostic (5.96e-2)" "unprognostic (3.03e-3)" "unprognostic (3.69e-1)" "unprognostic (4.29e-1)" "unprognostic (1.75e-1)" "prognostic favorable (7.61e-4)" "unprognostic (2.54e-1)" "unprognostic (3.49e-1)" "unprognostic (5.45e-3)" "unprognostic (2.32e-1)" "unprognostic (1.43e-1)" "unprognostic (2.46e-3)" "prognostic unfavorable (1.68e-4)" "unprognostic (1.74e-1)" "unprognostic (3.98e-2)" "unprognostic (2.08e-3)" 18.7 29.2 170.9 21.0 171.2 0.9 7.4 168.7 253.4 362.4 153.7 349.6 57.5 706.0 25.0 9.4 256.6 28.5 287.6 176.0 181.8 26.0 82.7 32.5 6.6 198.8 164.5 45.2 225.0 1.4 15.2 8.6 163.0 142.2 6.4 0.8 10.0 54.6 212.3 11.6 73.5 125.4 171.7 12.3 103.4 5.1 183.5 2.9 6.8 68.8 2.9 171.4 75.1 173.2 29.8 0.0 0.5 0.0 12.4 17.9 1.1 2.1 3.6 1.7 1.5 0.0 47.4 0.3 0.4 0.9 0.1 0.2 7.6 0.1 0.2 146.0 4.0 0.1 0.0 1.2 40.6 0.0 0.2 15.6 22.3 0.1 0.3 0.2 0.0 0.0 0.0 0.3 3.7 2.7 0.1 1.3 0.4 0.1 173.8 0.0 1.5 0.8 0.0 0.0 1.5 201.7 3.5 0.0 0.1 1.8 1.3 0.1 0.0 0.8 0.6 0.4 0.5 0.3 0.3 0.0 0.6 0.1 2.7 0.0 0.0 0.0 3.8 0.0 0.0 0.3 0.6 0.1 1.0 0.0 0.5 0.2 0.4 70.1 0.0 0.2 0.0 3.4 170.9 171.2 168.7 253.4 176.0 181.8 198.8 164.5 163.0 171.7 183.5 173.2 1.0 0.0 1.5 64.9 3.1 11.6 13.2 26.9 10.2 2.0 4.4 4.4 190.0 78.6 43.8 11.0 0.0 3.0 44.0 2.1 0.0 62.7 0.2 26.5 546.4 6.2 115.4 4.4 14.2 278.2 5.5 41.7 31.1 11.3 1.3 0.6 30.7 104.0 22.7 1.7 19.2 73.7 10.2 3.1 50.3 0.6 8.4 20.3 64.0 13.1 433.5 6.9 61.8 71.9 11.5 63.5 87.7 11.3 1.9 66.1 96.8 0.2 97.0 2.7 6.6 16.6 78.6 0.3 5.8 2.6 5.8 2.3 7.3 0.5 105.8 28.5 RCAN2 "DSCR1L1, ZAKI-4" ENSG00000172348 "Regulator of calcineurin 2" Q14206 6 46220736-46491972 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 199.5;tongue: 180.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 255.4;Excitatory neurons: 261.4;Inhibitory neurons: 254.4;Muller glia cells: 183.1;Oligodendrocytes: 294.6;Smooth muscle cells: 138.4" "Cancer enhanced" "Detected in all" "renal cancer: 25.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 17 "gdT-cell: 1.8;memory CD4 T-cell: 1.1;memory CD8 T-cell: 2.2;naive CD8 T-cell: 1.5" "Lineage enriched" "Detected in single" 23 "T-cells: 2.2" "Group enriched" "Detected in some" 6 "fHDF/TERT166: 63.3;HDLM-2: 129.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053880 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria Nucleoplasm "HPA053880: AB_2682290" "unprognostic (2.82e-1)" "unprognostic (7.76e-2)" "unprognostic (4.13e-2)" "unprognostic (1.14e-1)" "unprognostic (5.55e-3)" "unprognostic (4.52e-2)" "unprognostic (1.29e-3)" "unprognostic (1.86e-3)" "unprognostic (2.26e-1)" "unprognostic (4.33e-1)" "prognostic favorable (2.48e-4)" "unprognostic (1.37e-1)" "prognostic favorable (1.12e-6)" "unprognostic (3.83e-2)" "unprognostic (1.98e-1)" "unprognostic (1.02e-1)" "unprognostic (2.11e-2)" 38.1 12.6 35.7 7.7 41.2 0.0 17.1 31.7 106.3 20.3 0.0 20.1 9.8 17.5 51.5 25.9 17.0 35.1 199.5 34.0 65.0 32.4 4.9 16.3 4.1 69.6 76.0 24.0 11.1 85.5 17.5 0.6 68.8 25.3 22.6 61.6 9.6 27.0 73.3 17.2 19.1 14.0 20.6 7.1 36.5 5.7 65.5 4.7 20.1 180.1 7.0 44.0 21.4 62.3 0.0 0.0 1.6 0.0 0.7 0.2 0.1 1.1 15.1 1.1 0.1 0.0 0.0 0.0 0.8 63.3 0.0 0.1 0.0 0.0 0.3 129.7 0.8 0.0 0.0 0.0 1.0 0.0 0.0 1.2 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.1 5.1 0.0 0.0 0.2 2.7 0.4 0.4 0.4 13.6 0.1 0.2 0.3 4.9 0.0 0.0 0.0 0.0 3.0 0.0 0.1 0.0 0.1 1.8 0.1 0.2 6.8 0.1 0.0 0.2 0.0 0.4 0.0 0.0 0.0 1.8 0.0 0.0 0.0 1.1 2.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 35.7 41.2 31.7 106.3 34.0 65.0 69.6 76.0 68.8 20.6 65.5 62.3 7.6 6.4 5.8 13.7 0.6 6.2 4.6 0.0 0.0 24.8 1.8 1.4 255.4 8.6 0.0 3.7 4.2 0.1 0.8 1.0 70.5 5.5 40.2 0.8 0.4 17.1 25.1 0.0 261.4 2.5 0.0 22.2 1.5 0.8 0.0 0.3 0.4 1.2 0.1 30.3 254.4 1.5 34.6 0.3 8.0 14.2 29.2 0.9 32.0 46.9 0.0 183.1 0.0 76.9 294.6 2.9 0.3 50.4 0.4 3.3 0.0 1.9 0.0 9.7 98.6 16.4 138.4 1.5 1.4 0.5 7.4 0.0 4.0 0.8 0.3 1.4 SCUBE3 "CEGF3, FLJ34743" ENSG00000146197 "Signal peptide, CUB domain and EGF like domain containing 3" Q8IX30 6 35213956-35253079 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "thyroid gland: 28.9" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 10.8;Horizontal cells: 10.1;Rod photoreceptor cells: 7.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 26.0;ASC diff: 76.7;ASC TERT1: 102.2;HSkMC: 48.1;hTEC/SVTERT24-B: 30.1;U-138 MG: 29.1;WM-115: 25.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040606 Uncertain Approved "Plasma membrane" "Secreted to blood" NA NA 1890000 490000 "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "HPA040606: AB_10795383" "unprognostic (1.45e-1)" "unprognostic (1.79e-2)" "unprognostic (2.22e-1)" "unprognostic (2.41e-3)" "unprognostic (1.52e-1)" "unprognostic (1.27e-1)" "unprognostic (4.43e-2)" "unprognostic (5.01e-2)" "unprognostic (2.00e-2)" "unprognostic (7.41e-2)" "unprognostic (1.57e-1)" "unprognostic (2.64e-2)" "unprognostic (4.83e-8)" "unprognostic (1.54e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (1.38e-4)" "unprognostic (3.06e-3)" 1.7 2.4 0.7 0.9 1.1 0.1 0.4 2.0 1.0 0.5 2.9 4.2 0.1 0.6 0.9 0.7 0.8 0.5 3.4 0.5 0.6 2.9 0.1 0.7 0.1 0.8 1.0 0.5 0.1 0.1 1.7 0.7 0.3 2.2 0.9 1.4 0.2 4.5 0.3 0.8 0.7 0.9 0.1 0.2 1.4 1.1 0.7 0.1 28.9 0.0 0.2 5.1 0.9 0.8 0.0 0.1 26.0 0.2 76.7 102.2 0.3 6.7 3.3 0.1 0.1 0.5 0.1 0.0 0.9 15.5 0.0 0.0 5.3 0.0 0.4 0.0 0.1 0.0 0.7 0.1 0.1 0.0 0.0 48.1 0.0 30.1 0.0 0.5 0.0 0.0 0.1 0.2 0.2 0.3 0.0 0.0 1.2 0.0 0.4 0.1 0.0 0.0 0.1 2.9 0.5 0.0 0.1 0.7 1.9 10.2 0.7 0.1 1.5 29.1 1.3 0.0 0.2 0.1 0.0 0.0 4.6 0.0 25.2 0.3 0.1 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.1 0.2 0.1 0.0 0.7 1.1 2.0 1.0 0.5 0.6 0.8 1.0 0.3 0.1 0.7 0.8 0.2 0.0 0.6 0.7 0.5 0.0 0.2 0.4 0.0 2.6 0.3 0.0 3.5 0.0 2.0 1.8 2.1 1.2 0.5 0.0 0.0 0.0 2.1 1.2 0.4 0.6 10.8 0.0 2.2 0.0 2.1 1.3 0.0 0.4 1.3 0.5 0.0 0.1 0.3 10.1 3.2 0.1 0.0 0.6 0.4 3.3 0.9 0.2 1.8 0.0 0.1 3.0 0.0 4.0 3.5 0.1 0.0 3.8 0.4 0.1 0.0 0.1 0.9 7.1 0.0 0.6 3.2 0.5 2.1 0.0 0.0 0.7 0.2 0.1 0.0 0.2 SELENOM "SELM, SEPM" ENSG00000198832 "Selenoprotein M" Q8WWX9 22 31104772-31120069 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 373.6;Breast myoepithelial cells: 436.2;Collecting duct cells: 309.0;Distal tubular cells: 309.1;Endometrial stromal cells: 349.5;Exocrine glandular cells: 586.6;Smooth muscle cells: 225.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "B-cells: 154.8;T-cells: 233.0" "Cell line enhanced" "Detected in many" "BJ: 152.2;BJ hTERT+: 143.8;HHSteC: 183.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008667, HPA019601" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA 170000 "Cluster 20: T-cells - T-cell receptor" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" "CAB008667: AB_1622762, HPA019601: AB_1856666" "unprognostic (5.29e-3)" "unprognostic (1.68e-1)" "unprognostic (7.61e-2)" "unprognostic (1.32e-1)" "unprognostic (2.93e-2)" "unprognostic (1.02e-1)" "unprognostic (2.59e-3)" "unprognostic (1.45e-1)" "unprognostic (1.60e-2)" "unprognostic (1.60e-1)" "unprognostic (3.51e-3)" "unprognostic (8.31e-2)" "prognostic unfavorable (2.55e-6)" "unprognostic (1.32e-2)" "unprognostic (3.80e-1)" "unprognostic (5.20e-2)" "unprognostic (3.19e-2)" 241.8 95.4 126.7 55.7 126.7 2.9 239.8 127.3 170.7 458.8 189.9 575.4 37.2 600.2 14.8 86.1 437.8 28.6 227.2 130.0 149.3 162.5 36.7 157.5 25.9 137.1 138.6 262.4 154.3 94.7 241.1 32.2 131.0 339.6 16.4 8.1 198.8 140.1 109.9 114.8 193.9 85.3 139.6 97.6 285.6 42.1 142.1 10.2 225.8 18.6 15.3 462.3 290.7 132.3 12.8 25.7 7.4 42.7 68.8 80.5 82.2 152.2 143.8 69.2 50.0 0.8 2.0 1.6 30.9 89.9 31.2 1.2 6.9 9.2 4.7 7.0 25.6 2.7 7.8 13.3 183.7 0.0 13.1 78.5 27.1 33.1 12.6 33.1 9.0 2.2 2.4 14.7 17.9 6.6 0.5 1.4 9.6 11.8 27.3 0.1 0.1 18.1 11.1 0.1 16.2 35.7 47.3 41.6 0.7 2.5 57.5 0.9 30.9 20.8 59.0 77.8 0.1 13.2 6.5 1.0 83.1 0.2 13.8 18.3 10.5 5.1 105.3 19.9 137.9 154.8 174.5 127.0 6.4 129.5 233.0 137.8 8.2 39.1 40.1 2.5 179.0 102.6 126.7 126.7 127.3 170.7 130.0 149.3 137.1 138.6 131.0 139.6 142.1 132.3 168.6 54.5 126.5 0.0 38.8 0.0 0.0 0.0 0.0 0.0 373.6 436.2 0.0 0.0 32.2 309.0 0.0 11.7 23.2 0.0 309.1 101.2 0.0 22.8 349.5 61.8 0.0 0.0 0.0 586.6 149.5 161.3 0.0 18.1 30.3 30.8 0.0 0.0 22.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 42.9 0.0 0.0 0.0 0.0 166.2 0.0 0.0 22.3 0.0 0.0 152.5 20.4 0.0 0.0 0.0 225.6 0.0 0.0 0.0 0.0 23.4 24.8 30.5 0.0 0.0 SEPTIN5 "H5, HCDCREL-1, PNUTL1, SEPT5" ENSG00000184702 "Septin 5" Q99719 22 19714503-19724224 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 321.9" "Group enriched" "Detected in some" 9 "Cardiomyocytes: 3.4;Smooth muscle cells: 2.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 32 "eosinophil: 15.4;neutrophil: 5.8" "Lineage enriched" "Detected in single" 47 "granulocytes: 15.4" "Cell line enhanced" "Detected in many" "K-562: 281.6;THP-1: 75.9" "CAB016120, HPA029095, HPA063885" Enhanced Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA 860000 "Cluster 49: Eosinophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nucleoplasm, Actin filaments, Cytosol" "CAB016120: AB_628240, HPA029095: AB_2672904, HPA063885: AB_2685141" "unprognostic (4.07e-2)" "unprognostic (1.47e-1)" "unprognostic (6.78e-3)" "unprognostic (1.39e-2)" "unprognostic (3.92e-1)" "unprognostic (1.86e-1)" "unprognostic (2.50e-2)" "unprognostic (3.77e-1)" "unprognostic (5.66e-2)" "unprognostic (6.19e-2)" "unprognostic (1.88e-3)" "unprognostic (4.34e-1)" "prognostic unfavorable (6.87e-6)" "unprognostic (3.39e-2)" "unprognostic (2.93e-1)" "unprognostic (1.53e-2)" "unprognostic (3.30e-2)" 17.7 17.7 152.8 5.7 215.6 41.0 16.4 49.2 321.9 54.1 61.9 19.8 5.2 28.1 46.2 62.1 38.8 14.7 165.4 233.6 49.3 12.7 5.2 17.4 8.4 40.9 45.2 29.3 17.0 127.3 82.7 12.0 39.4 20.1 6.3 30.3 15.9 9.9 10.8 126.5 8.8 17.3 24.7 14.3 16.3 29.1 73.1 15.9 33.4 16.2 8.1 13.5 42.8 168.6 0.4 10.6 42.0 64.0 3.9 13.1 0.3 15.8 20.1 17.9 10.5 0.7 5.6 1.5 6.1 35.8 26.0 6.0 30.2 6.0 8.8 9.6 3.4 0.7 2.4 0.2 16.2 0.8 47.2 17.4 7.4 6.0 2.5 5.1 7.5 23.1 281.6 0.6 28.2 4.2 4.6 31.2 5.4 1.0 10.4 41.4 1.3 7.2 1.3 1.4 62.3 49.2 2.4 3.5 2.8 10.2 17.3 75.9 3.0 46.4 55.6 2.0 3.2 4.5 0.0 0.4 5.8 2.2 15.2 0.0 0.1 15.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 5.8 0.0 0.0 0.3 0.0 6.0 152.8 215.6 49.2 321.9 233.6 49.3 40.9 45.2 39.4 24.7 73.1 168.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SH3BGR 21-GARP ENSG00000185437 "SH3 domain binding glutamate rich protein" P55822 21 39445855-39515506 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "skeletal muscle: 1268.3;tongue: 578.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 180.2;Distal tubular cells: 46.9;Early spermatids: 151.2" "Cancer enhanced" "Detected in all" "glioma: 21.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 101.0" "Low region specificity" "Detected in all" CAB003685 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "CAB003685: AB_425682" "unprognostic (3.41e-2)" "unprognostic (1.26e-1)" "unprognostic (5.84e-3)" "unprognostic (1.68e-3)" "unprognostic (6.05e-2)" "unprognostic (6.12e-3)" "unprognostic (3.89e-2)" "unprognostic (9.78e-2)" "unprognostic (2.06e-1)" "unprognostic (6.97e-3)" "unprognostic (3.59e-2)" "unprognostic (4.75e-1)" "unprognostic (5.98e-3)" "unprognostic (7.16e-2)" "unprognostic (4.60e-2)" "unprognostic (1.68e-2)" "unprognostic (2.06e-2)" 8.9 24.0 41.8 3.6 44.9 2.0 11.2 42.0 72.4 10.8 37.3 39.4 6.6 12.3 28.5 20.3 8.1 9.5 154.1 43.7 43.0 13.2 11.8 5.4 2.0 43.8 40.8 6.0 11.0 10.7 25.6 2.1 44.4 25.1 7.0 14.7 14.2 21.2 1268.3 4.8 8.5 11.0 41.0 3.3 16.9 20.1 42.4 3.2 16.3 578.1 2.1 20.8 8.1 50.5 2.0 2.9 3.7 4.2 5.5 9.2 1.0 2.7 0.6 1.9 1.5 1.6 3.9 6.6 8.9 10.9 14.5 0.3 1.2 3.1 2.9 3.9 7.6 7.6 0.9 3.1 15.1 2.8 1.3 7.6 13.5 7.0 12.1 3.4 1.8 13.9 5.0 7.7 7.8 9.4 3.7 4.2 3.2 6.2 6.2 6.5 13.1 4.5 8.3 1.8 10.0 4.0 5.8 4.9 5.4 2.3 19.8 0.5 1.6 5.0 0.6 3.1 7.9 26.3 5.7 6.7 101.0 5.0 6.9 0.0 0.2 0.0 0.2 0.9 0.9 1.4 0.4 0.9 0.9 0.6 1.6 1.2 0.2 1.2 0.9 3.7 0.1 0.4 41.8 44.9 42.0 72.4 43.7 43.0 43.8 40.8 44.4 41.0 42.4 50.5 2.4 3.2 3.9 15.3 1.4 2.7 12.8 5.9 1.8 2.1 11.4 25.0 180.2 5.7 4.4 5.5 4.2 3.7 3.2 2.3 46.9 5.1 151.2 11.3 5.0 3.1 1.2 0.8 6.4 21.3 1.7 5.6 3.6 10.6 4.5 5.3 2.2 9.2 2.4 5.0 6.5 1.7 4.1 1.6 2.0 35.4 2.1 1.5 12.4 5.6 1.2 21.2 0.0 3.0 14.6 4.8 3.2 5.7 1.0 3.3 2.3 14.4 6.7 6.2 6.6 22.7 16.9 32.4 23.6 1.1 1.7 1.9 1.4 4.7 2.7 4.6 SLC6A8 "CRTR, CT1" ENSG00000130821 "Solute carrier family 6 member 8" P48029 X 153687926-153696588 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 142.0;Distal enterocytes: 382.0;Proximal enterocytes: 235.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 155.8;AN3-CA: 151.3;SK-BR-3: 156.8" "Low region specificity" "Detected in all" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (5.80e-2)" "unprognostic (1.24e-1)" "unprognostic (2.39e-2)" "unprognostic (9.98e-2)" "unprognostic (1.47e-1)" "unprognostic (7.16e-2)" "unprognostic (1.59e-2)" "unprognostic (1.59e-2)" "unprognostic (2.08e-1)" "unprognostic (2.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (7.39e-4)" "unprognostic (2.87e-1)" 31.6 66.6 77.2 9.0 99.4 34.5 23.9 77.8 80.0 17.5 39.9 73.5 51.3 32.4 13.0 54.6 17.3 31.3 130.4 76.8 82.1 81.4 4.5 9.2 1.9 89.0 90.5 12.4 20.0 45.6 21.4 36.2 76.9 31.3 30.5 34.7 52.3 35.9 166.6 45.9 75.9 20.7 71.3 13.1 30.8 38.5 87.6 11.9 8.2 75.5 3.0 41.2 36.5 116.6 155.8 6.7 39.5 151.3 14.7 9.9 10.2 22.2 37.7 28.7 35.5 20.1 2.1 0.2 17.0 27.9 33.6 54.3 85.3 78.0 17.0 2.7 83.3 0.6 50.6 59.7 50.0 1.2 10.1 20.9 16.5 27.3 103.3 50.7 14.9 0.9 37.3 2.4 15.7 9.3 0.8 3.6 47.0 30.9 67.0 7.6 5.2 2.1 30.8 29.5 56.0 64.2 33.8 156.8 107.9 9.8 30.9 23.9 14.1 45.2 73.1 58.2 66.5 5.2 3.0 1.8 105.5 4.5 47.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 77.2 99.4 77.8 80.0 76.8 82.1 89.0 90.5 76.9 71.3 87.6 116.6 5.9 0.0 1.9 14.0 2.7 23.2 14.3 91.1 13.1 142.0 19.6 18.4 106.9 21.5 55.6 5.5 110.5 15.3 2.8 382.0 3.9 4.6 1.5 21.4 38.9 6.5 25.9 23.4 8.2 22.2 37.7 8.8 6.1 16.1 4.5 14.4 3.9 0.9 4.9 119.5 9.9 44.2 38.7 1.9 5.7 3.7 9.0 4.1 24.9 2.8 3.2 19.0 0.0 9.0 23.7 47.5 101.1 8.2 0.8 28.3 235.8 53.3 31.3 49.3 32.9 15.6 19.0 2.9 3.9 16.9 15.6 90.8 2.9 1.5 20.7 18.6 SMTN ENSG00000183963 Smoothelin P53814 22 31064105-31104757 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 887.2;urinary bladder: 450.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 283.5;Hepatic stellate cells: 121.3;Sertoli cells: 184.1;Smooth muscle cells: 116.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "WM-115: 200.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001721, HPA051778, HPA058590" Enhanced Supported "Nucleoplasm,Actin filaments" No Yes 140000 "Cluster 30: Non-specific - Translation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "Actin filaments" "CAB001721: , HPA051778: AB_2681607, HPA058590: AB_2683765" "unprognostic (1.36e-2)" "unprognostic (4.84e-3)" "unprognostic (5.59e-2)" "unprognostic (1.96e-1)" "unprognostic (1.04e-1)" "unprognostic (1.41e-1)" "unprognostic (2.38e-3)" "unprognostic (1.08e-3)" "unprognostic (2.05e-2)" "unprognostic (4.56e-1)" "unprognostic (2.15e-1)" "unprognostic (7.22e-2)" "prognostic unfavorable (2.73e-5)" "unprognostic (2.75e-2)" "unprognostic (1.84e-1)" "unprognostic (8.41e-3)" "unprognostic (6.34e-2)" 54.7 19.2 10.8 25.3 12.5 4.7 42.2 10.3 13.1 100.2 7.6 887.2 30.0 251.0 7.0 65.1 132.4 20.8 152.0 9.0 9.3 35.6 15.3 38.2 5.6 11.7 12.5 34.0 25.2 3.3 9.8 17.4 11.0 150.9 29.2 15.2 16.3 177.9 95.7 38.7 151.5 127.2 10.5 54.5 231.2 12.5 12.4 2.9 26.4 26.2 2.5 450.6 91.5 10.0 73.0 21.2 7.2 27.0 11.0 17.2 58.0 106.8 49.1 85.7 58.4 29.9 22.4 32.1 9.3 59.3 17.3 10.6 7.2 62.8 40.4 10.6 58.2 33.9 18.3 36.1 9.7 51.5 57.4 14.2 5.8 114.0 18.7 29.2 74.7 12.3 37.3 25.9 59.6 64.5 5.9 11.4 8.2 36.1 90.0 20.3 20.5 34.6 34.5 23.2 11.5 12.7 33.4 15.9 15.7 7.4 18.8 8.2 118.7 62.1 58.4 59.4 79.8 24.6 32.5 18.8 91.0 19.7 200.5 0.0 1.0 0.0 0.1 0.2 0.0 1.3 0.1 0.3 0.4 0.0 1.0 0.5 0.1 0.1 0.2 0.2 0.0 0.6 10.8 12.5 10.3 13.1 9.0 9.3 11.7 12.5 11.0 10.5 12.4 10.0 94.5 6.4 3.3 23.8 2.0 65.1 33.5 16.1 19.4 46.6 18.6 26.7 39.5 5.7 6.1 9.2 283.5 13.4 2.7 12.8 9.8 14.8 1.2 4.0 52.1 62.8 29.2 0.0 0.2 20.1 68.8 35.9 18.3 7.3 0.0 11.0 121.3 2.6 6.0 5.0 1.9 29.9 14.2 6.8 14.6 1.9 22.4 4.7 14.2 7.5 1.0 31.2 1.0 4.5 2.0 73.2 11.4 48.5 2.1 21.7 5.6 18.4 2.2 54.0 184.1 18.4 116.4 5.7 7.9 9.7 69.3 21.9 3.7 16.3 27.0 14.9 SORBS1 "CAP, FLJ12406, KIAA1296, ponsin, SH3D5, sh3p12" ENSG00000095637 "Sorbin and SH3 domain containing 1" Q9BX66 10 95311771-95561414 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 800.2;Cardiomyocytes: 612.3;Excitatory neurons: 401.1;Inhibitory neurons: 295.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 6.1" "Lineage enriched" "Detected in single" 10 "granulocytes: 6.1" "Cell line enhanced" "Detected in many" "CACO-2: 28.0;Hep G2: 19.5;HMC-1: 48.3;SK-MEL-30: 45.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027559, CAB032850, HPA043084" Enhanced Supported "Plasma membrane,Focal adhesion sites,Centrosome" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Focal adhesion sites" "Plasma membrane, Centrosome" "CAB032850: AB_2286335, HPA027559: AB_10600812, HPA043084: AB_2678307" "prognostic favorable (2.84e-4)" "unprognostic (3.53e-1)" "unprognostic (1.89e-1)" "unprognostic (7.85e-2)" "unprognostic (3.43e-1)" "unprognostic (1.41e-1)" "unprognostic (2.98e-2)" "unprognostic (5.30e-2)" "unprognostic (1.95e-2)" "unprognostic (1.65e-2)" "unprognostic (3.17e-2)" "unprognostic (1.27e-1)" "unprognostic (3.40e-2)" "unprognostic (3.13e-2)" "unprognostic (1.80e-1)" "unprognostic (2.55e-2)" "unprognostic (5.01e-3)" 370.8 21.6 128.5 53.3 153.3 4.7 78.3 101.7 144.1 46.0 42.6 312.8 25.6 169.4 32.1 155.5 99.2 81.3 351.6 127.0 165.4 17.6 49.3 34.4 3.1 164.0 161.5 19.0 22.0 26.4 11.5 30.3 126.7 140.6 67.0 39.0 24.5 217.4 190.5 24.5 62.7 151.0 138.9 8.1 143.1 14.4 127.0 3.7 14.8 155.9 1.5 235.3 47.1 139.9 1.6 1.2 12.4 3.1 4.2 0.2 2.4 0.4 0.1 0.4 0.1 28.0 10.9 0.0 2.2 0.2 4.2 0.6 2.4 0.6 0.4 3.2 4.5 7.2 0.4 19.5 1.5 0.0 48.3 0.9 0.4 0.5 0.3 0.2 4.9 1.9 11.7 2.3 1.3 0.8 0.1 0.8 5.7 6.2 2.6 1.0 4.0 0.4 15.1 18.3 4.9 3.7 1.8 0.6 45.2 8.9 2.1 0.4 0.3 0.1 4.0 0.1 2.4 1.8 0.5 0.2 4.8 0.5 11.7 6.1 0.1 1.2 0.4 0.6 0.5 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.3 0.1 128.5 153.3 101.7 144.1 127.0 165.4 164.0 161.5 126.7 138.9 127.0 139.9 42.2 22.4 20.9 800.2 0.8 11.6 8.7 0.0 5.2 7.5 6.5 19.3 612.3 12.8 1.3 1.8 2.1 20.2 1.0 4.0 3.9 7.2 70.4 1.4 15.8 25.7 6.0 16.0 401.1 3.1 2.4 21.4 8.6 1.6 16.4 8.2 30.4 50.5 3.1 6.7 295.1 10.9 0.0 3.8 12.0 48.6 7.5 1.1 14.2 163.9 0.7 22.1 1.0 155.3 22.6 2.3 2.8 76.8 1.1 4.7 1.2 6.1 0.1 5.5 0.0 11.8 51.6 3.4 3.7 1.9 12.5 29.6 1.6 0.1 5.1 5.9 SYNPO2 MYOPODIN ENSG00000172403 "Synaptopodin 2" Q9UMS6 4 118850688-119061247 "Predicted intracellular proteins" "Actin-binding, Muscle protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 991.6;tongue: 493.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 135.4;Endometrial stromal cells: 130.0;Excitatory neurons: 149.6;Peritubular cells: 101.5;Sertoli cells: 131.5;Skeletal myocytes: 93.4;Smooth muscle cells: 206.1" "Group enriched" "Detected in all" 5 "prostate cancer: 25.7;stomach cancer: 27.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 57.8;LHCN-M2: 18.5;SH-SY5Y: 83.2" "Region enriched" "Detected in all" 4 "thalamus: 27.1" "Low region specificity" "Detected in all" "HPA030665, CAB037231, HPA049707, HPA068563" Enhanced Enhanced "Vesicles,Actin filaments" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Vesicles, Actin filaments" "CAB037231: AB_262098, HPA030665: AB_10696210, HPA049707: AB_2680857, HPA068563: AB_2686006" "unprognostic (1.50e-2)" "unprognostic (1.73e-2)" "unprognostic (5.32e-2)" "unprognostic (1.50e-2)" "unprognostic (1.81e-1)" "unprognostic (2.39e-1)" "unprognostic (5.71e-4)" "unprognostic (2.18e-1)" "unprognostic (3.07e-1)" "unprognostic (3.52e-1)" "unprognostic (1.39e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (5.67e-5)" "unprognostic (1.82e-2)" "unprognostic (1.35e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.91e-4)" 57.5 10.8 6.1 47.4 7.9 0.3 35.9 4.1 5.7 55.0 2.2 346.4 34.3 137.1 33.4 197.1 89.5 50.0 66.8 10.7 13.3 8.7 7.0 16.2 10.5 5.4 7.5 39.0 3.8 3.6 7.5 20.8 6.1 180.5 58.0 1.2 16.0 267.4 991.6 17.9 75.5 244.4 9.2 10.2 126.2 6.7 5.8 14.3 16.0 493.5 6.5 226.5 54.0 12.0 0.2 4.2 0.2 0.0 10.5 3.5 0.7 13.4 14.1 0.4 0.5 0.0 0.7 1.5 0.1 57.8 0.9 0.2 0.4 0.3 0.7 5.9 0.1 0.8 1.3 0.0 2.4 0.1 0.2 14.5 0.3 4.0 0.2 3.7 0.2 0.2 0.0 0.7 18.5 0.3 0.7 7.2 1.4 0.0 0.0 0.5 1.5 0.4 0.2 0.3 0.4 83.2 0.4 0.3 0.1 3.3 0.0 7.0 0.4 0.6 0.1 0.2 0.1 0.1 0.3 0.1 1.1 0.6 0.2 0.8 0.1 0.5 0.2 0.0 0.4 0.3 0.4 0.2 0.0 0.4 0.4 0.3 0.2 0.3 0.1 0.0 0.5 0.1 6.1 7.9 4.1 5.7 10.7 13.3 5.4 7.5 6.1 9.2 5.8 12.0 25.5 3.2 1.1 42.7 1.1 13.5 17.9 3.7 46.1 2.5 6.3 30.7 135.4 0.0 0.3 1.8 0.0 1.4 0.5 0.1 0.0 0.1 2.2 6.9 130.0 11.3 0.0 1.7 149.6 1.8 0.5 41.5 0.5 10.6 0.0 16.1 13.9 0.4 1.4 0.0 31.5 0.2 0.0 0.9 11.4 7.0 27.1 3.8 5.4 76.8 12.9 0.0 0.0 6.0 3.0 0.2 0.4 101.5 0.8 24.9 0.1 0.3 2.5 0.5 131.5 93.4 206.1 1.3 0.5 5.3 8.1 0.8 2.6 33.4 0.2 4.0 TINAGL1 "ARG1, LCN7, LIECG3, P3ECSL, TINAGRP" ENSG00000142910 "Tubulointerstitial nephritis antigen like 1" Q9GZM7 1 31576485-31587686 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1235.1;Sertoli cells: 427.3;Syncytiotrophoblasts: 1946.1" "Cancer enhanced" "Detected in all" "urothelial cancer: 87.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.0" "Cell line enhanced" "Detected in many" "BEWO: 322.7;CAPAN-2: 178.9;EFO-21: 403.6;HaCaT: 181.4;HBEC3-KT: 211.9;HUVEC TERT2: 173.4;TIME: 376.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048695 Approved "Secreted to extracellular matrix" NA NA 370000 "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA048695: AB_2680497" "unprognostic (1.27e-1)" "unprognostic (2.94e-2)" "unprognostic (7.53e-2)" "unprognostic (1.80e-3)" "unprognostic (2.74e-1)" "unprognostic (1.72e-3)" "unprognostic (8.29e-3)" "unprognostic (6.02e-3)" "unprognostic (4.18e-1)" "unprognostic (6.96e-2)" "unprognostic (7.02e-3)" "unprognostic (1.22e-1)" "prognostic favorable (3.65e-6)" "unprognostic (7.42e-2)" "unprognostic (6.64e-2)" "prognostic favorable (9.64e-4)" "unprognostic (3.43e-2)" 173.7 40.8 19.0 18.5 17.7 0.9 150.5 17.9 19.9 86.8 16.4 83.2 26.7 101.8 10.7 31.0 82.4 23.9 230.7 15.2 17.9 177.7 22.7 85.7 8.5 19.6 18.3 38.8 31.0 13.2 25.3 183.6 19.8 71.2 16.5 1.0 63.8 40.6 46.6 37.0 51.6 36.5 16.4 119.6 66.4 6.2 21.2 3.8 115.1 30.6 5.3 88.4 70.2 17.1 96.6 0.2 0.0 0.5 0.8 0.2 322.7 14.9 1.9 0.7 0.4 44.5 178.9 0.2 403.6 13.4 7.0 181.4 0.2 211.9 0.1 0.7 0.1 0.1 7.3 11.5 4.5 0.1 0.5 0.2 37.9 0.0 7.6 0.1 173.4 0.1 2.4 0.4 0.0 0.0 0.7 0.6 0.9 52.6 6.1 0.4 0.1 0.4 57.0 72.6 0.4 0.5 38.0 125.6 4.2 18.8 7.5 0.3 376.6 0.3 91.6 0.7 2.8 0.4 0.5 1.6 0.2 0.2 3.3 2.0 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.2 0.2 0.8 0.4 0.1 0.1 0.1 0.0 19.0 17.7 17.9 19.9 15.2 17.9 19.6 18.3 19.8 16.4 21.2 17.1 345.4 9.6 5.8 0.7 2.7 11.0 121.5 244.1 8.0 0.0 32.0 73.0 46.7 37.1 28.6 132.4 0.0 1235.1 2.6 158.9 1.9 378.7 1.4 8.4 3.2 161.4 11.4 13.5 0.1 92.2 223.5 35.0 50.0 14.4 14.7 49.7 306.6 4.4 89.3 0.0 1.1 35.5 14.2 8.8 10.3 0.7 7.5 4.2 23.2 13.1 2.0 0.2 0.0 0.5 0.0 344.6 115.3 4.1 0.2 131.4 45.2 80.9 9.1 0.4 427.3 9.5 357.4 0.3 0.8 4.9 6.5 1946.1 3.8 2.7 59.7 219.4 WFDC1 PS20 ENSG00000103175 "WAP four-disulfide core domain 1" Q9HC57 16 84294846-84329844 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 99.8;seminal vesicle: 115.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 111.1;Fibroblasts: 72.6;Peritubular cells: 257.3;Smooth muscle cells: 95.8;Theca cells: 325.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 29.8;BJ: 20.5;HEL: 18.2;HeLa: 27.6;THP-1: 9.9;U-937: 10.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031411 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "HPA031411: AB_10600921" "unprognostic (6.53e-2)" "unprognostic (1.27e-1)" "unprognostic (1.61e-2)" "unprognostic (8.66e-4)" "unprognostic (1.41e-2)" "unprognostic (1.50e-3)" "unprognostic (1.47e-2)" "unprognostic (3.11e-2)" "unprognostic (1.60e-1)" "unprognostic (2.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (3.78e-2)" "unprognostic (5.49e-2)" "unprognostic (1.71e-1)" "unprognostic (6.74e-2)" "unprognostic (3.04e-1)" 8.1 26.9 16.5 10.5 16.5 1.9 4.3 19.1 21.2 21.5 12.9 79.3 8.9 17.3 18.8 24.5 7.9 35.1 4.4 16.1 15.5 16.7 5.5 29.5 0.6 17.0 16.2 3.7 1.0 0.4 5.7 99.8 15.3 69.0 17.4 8.4 6.2 115.1 1.2 3.2 14.6 32.2 14.9 3.5 20.8 12.5 16.3 0.3 4.8 1.6 0.8 54.2 13.5 14.9 0.0 0.0 4.4 29.8 0.0 0.1 0.2 20.5 2.5 0.0 0.0 0.0 0.0 0.0 5.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 27.6 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.5 0.0 0.4 0.0 0.0 2.3 0.0 0.0 5.3 0.1 0.0 0.5 3.2 0.1 0.1 9.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.5 16.5 19.1 21.2 16.1 15.5 17.0 16.2 15.3 14.9 16.3 14.9 3.4 3.2 0.5 9.1 0.0 1.8 0.9 0.1 0.0 111.1 2.0 0.9 1.4 0.0 0.1 1.8 0.0 2.1 0.1 0.9 11.7 0.0 27.8 0.6 10.6 3.9 4.2 0.0 4.1 0.0 2.0 72.6 7.7 0.5 0.0 0.2 12.5 0.0 6.6 5.0 0.9 4.7 0.0 0.0 3.0 41.1 15.8 2.3 0.0 2.8 0.0 1.4 0.0 29.1 0.6 0.1 0.6 257.3 0.3 1.3 0.4 1.3 0.7 4.2 0.0 1.0 95.8 5.5 0.9 0.1 0.4 3.8 0.5 325.9 3.1 1.0