Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ACAA2 DSAEC ENSG00000167315 "Acetyl-CoA acyltransferase 2" P42765 18 49782164-49813953 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1011.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 331.1;Hepatocytes: 810.5;Proximal tubular cells: 708.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042303 Approved Supported Mitochondria NA NA 3800000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA042303: AB_10794046" "unprognostic (7.94e-2)" "unprognostic (3.14e-2)" "unprognostic (2.20e-3)" "prognostic unfavorable (8.53e-4)" "unprognostic (2.92e-2)" "unprognostic (2.28e-2)" "unprognostic (7.63e-2)" "unprognostic (1.70e-1)" "unprognostic (7.97e-2)" "unprognostic (8.03e-3)" "unprognostic (1.72e-1)" "unprognostic (3.84e-1)" "prognostic favorable (1.36e-10)" "unprognostic (1.39e-1)" "unprognostic (2.24e-1)" "unprognostic (8.26e-3)" "unprognostic (3.41e-1)" 126.3 74.2 56.9 44.4 64.9 32.5 79.1 63.7 63.9 24.9 68.4 168.7 170.0 29.0 29.8 30.3 24.4 46.9 223.7 53.2 59.8 378.2 1011.9 48.9 36.6 65.1 61.4 34.8 54.1 35.1 34.9 29.6 64.0 26.4 109.6 31.9 20.3 34.0 165.3 28.0 165.2 44.5 62.8 33.6 37.4 37.7 64.3 39.9 55.8 236.6 31.9 41.6 28.6 64.2 3.9 70.5 110.0 97.5 129.9 69.5 57.4 35.2 52.4 53.6 41.2 146.3 58.9 61.1 73.5 117.5 56.7 4.8 176.8 21.0 51.4 190.5 50.4 45.5 79.0 171.4 62.5 0.7 78.3 91.7 6.7 84.8 26.2 44.6 90.0 87.7 42.5 54.7 147.5 81.8 2.7 89.7 101.5 24.8 26.7 150.8 233.0 217.6 177.7 2.8 163.4 130.9 2.7 76.2 5.6 82.1 45.7 60.0 48.1 49.8 60.5 67.8 36.4 112.3 139.7 157.3 35.0 85.7 47.1 53.0 87.4 96.1 99.2 106.5 123.0 43.2 58.3 88.7 103.2 36.3 50.2 73.2 8.3 120.0 108.1 50.1 76.4 112.7 56.9 64.9 63.7 63.9 53.2 59.8 65.1 61.4 64.0 62.8 64.3 64.2 28.4 38.5 47.3 11.8 31.4 3.6 14.2 15.5 11.4 6.7 25.0 25.5 189.9 234.4 23.7 55.2 4.2 36.5 48.2 331.1 295.4 148.5 71.2 7.9 33.9 30.0 40.1 53.6 1.7 45.7 56.0 47.3 23.9 7.7 45.1 63.3 41.4 810.5 109.6 1.7 4.6 73.0 24.4 64.8 18.5 153.9 48.1 50.6 19.6 13.1 57.2 62.2 106.1 4.5 8.7 101.8 161.2 37.2 41.2 9.8 226.6 708.0 26.4 29.5 19.7 42.1 34.9 51.1 42.7 11.1 4.8 27.0 52.2 93.0 144.8 9.6 AIF1 "AIF-1, Em:AF129756.17, IBA1, IRT-1" ENSG00000204472 "Allograft inflammatory factor 1" P55008 6 31615217-31617021 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 235.0;lymphoid tissue: 346.6" "Group enriched" "Detected in many" 22 "Hofbauer cells: 1777.1;Kupffer cells: 2140.2;Langerhans cells: 1359.1;Macrophages: 1494.0;monocytes: 1022.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 26 "classical monocyte: 3823.3;intermediate monocyte: 6550.1;myeloid DC: 2043.3;neutrophil: 2943.0;non-classical monocyte: 7744.5" "Group enriched" "Detected in all" 74 "dendritic cells: 2043.3;granulocytes: 2943.0;monocytes: 7744.5" "Group enriched" "Detected in some" 4 "HEL: 204.6;HMC-1: 329.6;NB-4: 264.7;THP-1: 184.2;U-937: 114.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049234, HPA062949" Enhanced Uncertain Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "HPA049234: AB_2680685, HPA062949: AB_2732694" "unprognostic (3.20e-2)" "unprognostic (7.21e-3)" "unprognostic (6.11e-2)" "unprognostic (2.33e-2)" "unprognostic (2.46e-1)" "unprognostic (1.13e-1)" "unprognostic (6.98e-2)" "unprognostic (4.83e-2)" "unprognostic (2.72e-2)" "unprognostic (7.56e-2)" "unprognostic (1.41e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.29e-1)" "unprognostic (1.02e-2)" "unprognostic (9.59e-2)" "unprognostic (4.89e-2)" 79.6 46.6 24.9 182.3 25.5 235.0 47.2 26.6 33.0 29.3 32.2 48.3 36.4 17.1 12.1 18.7 19.7 61.3 21.1 25.0 31.3 74.3 81.2 99.3 116.8 45.1 36.4 14.4 12.4 12.9 17.3 109.5 36.8 22.3 57.2 3.9 20.3 24.0 6.1 11.7 44.5 74.7 34.3 346.6 22.2 8.7 32.1 69.1 13.8 16.6 57.1 95.3 13.5 42.7 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 204.6 0.0 0.0 0.0 30.0 329.6 0.0 0.0 0.0 0.0 0.0 0.0 51.6 0.9 0.2 0.0 0.0 2.3 264.7 0.4 0.0 0.0 35.9 0.4 8.9 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 184.2 0.1 0.0 0.2 0.1 0.3 0.2 0.0 1.3 0.2 114.6 0.0 33.1 3823.3 177.9 10.2 6550.1 12.7 57.5 10.8 9.3 2043.3 6.3 33.1 26.2 2943.0 14.5 7744.5 144.2 10.7 4449.8 24.9 25.5 26.6 33.0 25.0 31.3 45.1 36.4 36.8 34.3 32.1 42.7 12.0 25.6 59.6 0.0 39.2 32.5 0.7 0.0 0.6 0.1 5.3 24.3 7.5 18.6 19.2 42.3 0.0 11.1 31.2 1.0 0.0 0.3 1.9 0.6 0.7 28.7 1.2 65.0 0.0 0.4 15.4 20.6 0.5 0.4 68.3 0.4 35.3 13.4 1777.1 0.0 0.0 0.1 0.0 2140.2 1359.1 4.9 7.5 1494.0 39.2 10.3 1022.6 0.0 32.0 0.5 0.1 0.2 11.1 0.7 7.2 0.4 0.3 4.2 10.2 0.1 52.6 4.7 6.5 0.5 1.5 2.1 28.3 22.7 46.1 1.9 0.6 0.3 AIFM1 "AIF, AUNX1, CMTX4, DFNX5, NAMSD, PDCD8" ENSG00000156709 "Apoptosis inducing factor mitochondria associated 1" O95831 X 130124666-130165879 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "DNA-binding, Oxidoreductase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Dwarfism, Mental retardation, Neurodegeneration, Neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 165.4;Proximal tubular cells: 326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003764, HPA030611" Enhanced Supported Mitochondria NA NA 230000 "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB003764: AB_289587, HPA030611: AB_2673549" "unprognostic (3.00e-3)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.22e-1)" "unprognostic (2.10e-2)" "unprognostic (3.15e-3)" "unprognostic (1.46e-1)" "unprognostic (1.14e-2)" "unprognostic (1.43e-1)" "unprognostic (3.11e-2)" "unprognostic (2.54e-3)" "unprognostic (2.81e-3)" "prognostic favorable (4.42e-10)" "unprognostic (1.76e-2)" "unprognostic (1.14e-1)" "unprognostic (5.04e-2)" "unprognostic (2.11e-2)" 21.0 65.2 10.5 17.6 11.2 11.8 17.8 11.9 12.8 15.7 24.7 34.3 52.9 15.3 8.9 20.8 22.1 10.1 107.7 10.9 11.6 97.3 110.6 13.9 16.2 11.3 11.0 11.9 27.8 29.7 16.2 10.3 11.4 14.8 15.9 8.5 18.6 7.6 68.9 15.2 29.9 10.1 11.2 20.3 41.2 30.3 12.1 18.5 14.7 25.2 11.0 18.4 13.4 11.6 52.8 95.4 22.6 85.2 24.1 14.6 50.0 28.6 19.0 33.5 25.2 55.8 36.4 105.0 113.3 17.5 39.3 47.2 61.3 33.3 12.7 48.2 73.4 61.6 59.1 68.9 34.0 51.5 63.5 26.1 21.7 34.5 22.0 12.1 27.2 83.4 62.6 50.7 13.1 96.7 57.6 74.5 24.4 53.6 65.1 55.6 31.7 132.7 60.8 36.6 46.0 28.2 35.5 68.0 67.5 13.2 46.0 40.8 31.7 20.5 20.4 63.9 58.7 24.2 45.0 47.5 25.3 86.4 33.4 4.1 21.0 14.1 11.8 26.6 13.1 14.6 12.8 14.6 31.7 10.3 12.7 12.6 2.4 20.7 24.8 14.7 17.9 12.4 10.5 11.2 11.9 12.8 10.9 11.6 11.3 11.0 11.4 11.2 12.1 11.6 12.6 16.0 20.1 17.0 17.1 8.7 8.2 25.0 9.1 19.3 13.0 8.3 165.4 22.8 21.2 40.5 22.9 58.0 14.2 31.6 92.0 24.9 1.8 36.7 17.3 11.5 9.6 26.3 10.8 20.5 29.0 16.4 27.0 50.4 10.8 33.1 14.3 92.3 38.0 15.2 12.1 24.0 34.6 14.4 7.4 4.9 17.4 16.8 10.6 8.4 16.6 17.2 20.6 8.0 19.6 18.0 18.9 17.3 19.2 7.9 45.6 326.1 21.3 48.1 6.6 11.3 39.3 10.2 32.0 17.1 6.8 39.7 15.8 45.9 37.2 9.8 ALOX15B 15-LOX-2 ENSG00000179593 "Arachidonate 15-lipoxygenase type B" O15296 17 8039034-8049134 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 111.7;prostate: 73.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 75.8;Basal respiratory cells: 22.0;Kupffer cells: 42.2;monocytes: 87.9;Prostatic glandular cells: 25.6;Squamous epithelial cells: 44.4" "Cancer enriched" "Detected in all" 5 "prostate cancer: 91.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 8 "classical monocyte: 3.9;myeloid DC: 4.3" "Group enriched" "Detected in many" 8 "dendritic cells: 4.3;monocytes: 3.9" "Cell line enhanced" "Detected in some" "HHSteC: 7.7;HSkMC: 16.6;hTCEpi: 35.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010562 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane, Cytosol" "HPA010562: AB_2668305" "unprognostic (1.76e-2)" "unprognostic (6.47e-2)" "unprognostic (2.56e-1)" "unprognostic (2.28e-3)" "unprognostic (1.67e-2)" "unprognostic (1.52e-1)" "unprognostic (1.34e-1)" "unprognostic (1.52e-1)" "unprognostic (2.28e-1)" "unprognostic (1.85e-1)" "unprognostic (1.44e-2)" "unprognostic (4.59e-1)" "unprognostic (1.59e-2)" "unprognostic (9.37e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (9.49e-2)" 2.2 1.7 0.7 1.3 0.7 0.4 111.7 0.6 2.5 12.0 0.5 2.3 0.1 1.1 0.9 39.1 1.6 0.7 0.7 0.7 0.8 0.5 0.4 24.5 2.9 1.8 0.9 0.7 1.4 0.2 0.5 1.2 1.6 73.1 0.3 0.3 3.7 0.1 0.3 36.9 3.7 0.1 0.9 3.8 4.4 0.5 0.9 0.7 1.9 0.1 7.6 1.7 33.4 1.9 0.1 0.0 0.0 0.1 0.5 0.7 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 16.6 35.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.9 0.7 0.7 0.6 2.5 0.7 0.8 1.8 0.9 1.6 0.9 0.9 1.9 1.4 0.0 75.8 0.0 0.3 3.1 0.6 22.0 7.4 0.0 19.8 12.3 0.3 1.5 8.2 0.0 0.0 0.2 0.2 0.2 0.0 0.1 1.3 0.0 0.8 0.4 0.0 0.0 0.2 0.4 0.0 0.2 0.0 0.2 1.3 0.0 0.7 0.3 4.2 0.0 0.0 0.0 2.0 42.2 1.1 0.8 0.0 15.4 5.4 0.0 87.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.4 25.6 0.0 0.0 2.2 0.0 0.0 0.1 1.3 0.6 0.8 44.4 1.1 0.8 0.0 0.0 0.0 2.2 ALOX5AP FLAP ENSG00000132965 "Arachidonate 5-lipoxygenase activating protein" P20292 13 30713478-30764426 "Disease related genes, Predicted membrane proteins" "Leukotriene biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 487.2;lung: 183.3;lymphoid tissue: 138.5" "Cell type enhanced" "Detected in many" "dendritic cells: 691.3;granulocytes: 609.1;Hofbauer cells: 492.2;Langerhans cells: 335.4;Macrophages: 637.0;NK-cells: 280.2;T-cells: 368.6" "Cancer enhanced" "Detected in all" "glioma: 49.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 9703.9;eosinophil: 4033.4;neutrophil: 4968.7;plasmacytoid DC: 3555.3" "Group enriched" "Detected in all" 8 "dendritic cells: 3555.3;granulocytes: 9703.9" "Cell line enhanced" "Detected in many" "HDLM-2: 658.4;HL-60: 352.3;HMC-1: 1072.9;THP-1: 434.2;U-937: 321.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026592 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA026592: AB_10601115" "unprognostic (1.17e-2)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (4.64e-3)" "unprognostic (7.18e-2)" "unprognostic (7.10e-2)" "unprognostic (7.79e-2)" "unprognostic (1.04e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (6.44e-4)" "unprognostic (7.83e-2)" "unprognostic (6.63e-2)" "prognostic unfavorable (5.68e-4)" "unprognostic (1.33e-1)" "unprognostic (3.19e-2)" "unprognostic (2.72e-2)" "unprognostic (2.59e-1)" 51.6 36.1 10.8 100.6 11.6 487.2 25.7 12.5 18.1 18.8 13.4 22.8 21.6 17.4 7.1 21.8 24.5 40.0 12.4 10.2 15.7 13.3 19.7 183.3 77.2 21.0 15.6 10.6 14.1 9.6 6.1 37.2 21.1 13.2 21.4 3.7 19.9 15.5 3.8 7.4 28.3 42.6 16.6 138.5 20.0 4.3 17.7 93.2 9.1 24.7 108.2 65.6 11.9 31.3 0.6 0.8 1.2 0.0 0.6 0.0 0.1 0.0 0.4 0.0 0.0 1.3 7.1 156.3 2.2 0.0 5.2 1.2 0.0 4.6 0.1 658.4 0.0 18.7 0.3 1.0 0.7 352.3 1072.9 0.8 0.2 0.1 37.9 8.1 1.4 33.3 0.1 3.2 1.9 0.1 19.8 12.7 0.0 0.0 0.2 3.2 3.9 12.4 1.4 0.3 10.2 0.1 0.2 0.3 0.9 2.3 0.0 434.2 1.1 0.0 3.2 0.3 2.6 66.2 0.5 103.8 1.0 321.1 1.4 9703.9 322.4 4033.4 546.0 17.2 808.3 477.9 536.4 449.0 198.5 489.2 271.6 260.7 4968.7 98.0 12.4 3555.3 843.9 775.2 10.8 11.6 12.5 18.1 10.2 15.7 21.0 15.6 21.1 16.6 17.7 31.3 3.5 41.7 102.0 0.0 117.6 23.7 2.6 1.8 1.2 0.0 3.3 9.1 4.1 10.0 23.7 0.0 0.0 3.1 691.3 4.0 15.6 2.3 5.6 14.3 0.7 17.2 26.4 27.1 0.4 1.0 4.0 11.2 21.4 0.7 609.1 1.9 7.1 1.8 492.2 0.0 0.4 2.0 4.1 144.3 335.4 4.5 4.7 637.0 42.7 13.1 217.1 0.1 280.2 0.5 0.3 6.4 3.1 4.1 31.1 1.5 7.3 2.0 11.1 0.1 32.9 4.4 4.0 0.4 1.1 1.7 24.7 4.9 368.6 0.0 2.0 1.4 APOC2 ENSG00000234906 "Apolipoprotein C2" P02655 19 44946035-44949565 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Lipid transport, Transport" "Disease variant, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 83 "liver: 9641.4" "Cell type enriched" "Detected in some" 34 "Hepatocytes: 1170.2" "Cancer enriched" "Detected in some" 17 "liver cancer: 49.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 30 "NK-cell: 3.2" "Lineage enriched" "Detected in single" 30 "NK-cells: 3.2" "Group enriched" "Detected in many" 4 "Hep G2: 713.0;THP-1: 1354.4" HPA055877 Supported "Secreted to blood" NA NA 43000000000 49000000000 "Cluster 48: NK-cells - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" "HPA055877: AB_2682953" "unprognostic (4.28e-2)" "unprognostic (7.73e-3)" "unprognostic (1.33e-1)" "unprognostic (3.66e-2)" "unprognostic (8.91e-2)" "unprognostic (1.90e-1)" "unprognostic (2.07e-1)" "unprognostic (5.41e-2)" "unprognostic (2.56e-1)" "unprognostic (1.96e-2)" "unprognostic (2.86e-1)" "unprognostic (1.15e-2)" "unprognostic (5.14e-8)" "unprognostic (1.32e-1)" "unprognostic (1.45e-1)" "unprognostic (1.77e-2)" "unprognostic (9.80e-3)" 1.2 5.4 49.5 1.7 55.2 1.1 5.3 55.1 116.2 4.5 44.7 4.3 41.4 1.2 4.8 2.4 4.3 3.7 0.8 50.7 69.2 16.3 9641.4 34.9 15.8 65.3 64.9 0.4 2.2 6.6 3.0 2.9 74.3 1.3 4.4 2.8 2.4 2.1 1.9 4.3 65.6 0.7 63.3 3.9 2.7 1.1 59.9 3.2 0.9 0.7 9.9 2.2 0.8 75.0 2.9 0.6 0.3 0.4 0.5 0.6 1.3 0.1 0.0 0.0 0.1 2.0 2.8 0.7 0.3 0.0 0.0 2.6 0.0 0.1 0.0 0.7 0.1 123.0 2.7 713.0 0.2 15.4 237.5 0.2 0.3 0.0 0.0 0.3 0.0 0.1 1.7 2.9 0.1 0.8 0.9 126.3 0.5 3.2 0.4 0.8 5.2 1.1 0.0 1.5 0.1 0.1 1.9 0.2 7.7 0.0 0.7 1354.4 0.0 0.3 0.6 0.8 0.8 2.3 0.9 2.2 0.2 3.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 49.5 55.2 55.1 116.2 50.7 69.2 65.3 64.9 74.3 63.3 59.9 75.0 0.1 0.0 2.3 0.0 1.2 0.6 0.0 0.0 0.0 0.0 0.1 0.3 0.1 11.5 0.0 3.7 0.0 0.1 0.1 0.0 3.9 0.0 0.0 0.0 0.1 0.3 0.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 26.0 0.0 13.6 1170.2 33.8 0.0 0.0 0.4 0.0 15.5 1.2 0.0 0.0 24.0 7.2 0.0 2.0 0.0 0.0 0.0 0.0 0.0 10.0 0.7 0.0 0.1 17.7 32.3 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.4 0.3 1.8 0.0 1.3 0.0 APOE AD2 ENSG00000130203 "Apolipoprotein E" P02649 19 44905791-44909393 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Hyperlipidemia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adrenal gland: 3453.9;liver: 6592.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 9363.4;Hofbauer cells: 6072.6;Muller glia cells: 9454.8;Peritubular cells: 4958.2;Proximal tubular cells: 8155.9;Theca cells: 7201.0" "Cancer enhanced" "Detected in all" "liver cancer: 3183.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1867.0;CACO-2: 466.1;Hep G2: 935.3;HSkMC: 1374.2;SK-MEL-30: 1956.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008363, HPA065539, HPA068768, CAB069921" Enhanced Approved Vesicles "Secreted to blood" NA NA 51800000000 29000000000 "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB008363: AB_590560, CAB069921: AB_920623, HPA065539: AB_2685509, HPA068768: AB_2686029" "unprognostic (8.98e-2)" "unprognostic (2.32e-2)" "unprognostic (2.49e-2)" "unprognostic (5.28e-2)" "unprognostic (3.77e-2)" "unprognostic (7.25e-2)" "unprognostic (5.22e-3)" "unprognostic (6.13e-2)" "unprognostic (5.06e-2)" "unprognostic (4.13e-1)" "unprognostic (5.78e-2)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (7.76e-2)" "unprognostic (1.64e-1)" "unprognostic (1.12e-3)" "unprognostic (4.13e-2)" 522.1 3453.9 813.4 92.8 1164.2 66.5 325.1 775.0 943.2 271.2 329.2 130.9 40.3 81.5 20.0 37.2 72.2 100.2 176.3 606.1 841.6 1066.0 6592.5 258.8 352.2 1016.0 1037.0 508.2 41.9 34.5 110.9 102.2 1106.9 45.4 22.9 87.6 80.5 10.8 31.1 381.2 165.9 12.6 823.2 620.3 83.3 140.5 962.6 57.8 146.4 10.4 46.1 93.4 135.5 964.4 3.2 5.2 9.5 2.6 1867.0 76.3 69.4 1.5 4.3 8.4 1.4 466.1 2.8 2.0 9.9 0.3 9.1 6.4 12.6 2.1 0.7 1.7 4.0 3.3 1.7 935.3 192.4 6.8 2.3 1374.2 2.5 14.8 1.3 15.6 1.0 0.7 124.9 2.8 1.2 3.3 1.9 2.5 243.2 3.0 1.3 2.6 8.0 1.8 2.8 0.9 5.6 2.4 4.5 1.4 1956.0 131.6 165.3 52.8 3.3 13.2 3.1 1.4 1.6 5.9 8.6 3.8 5.9 4.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 813.4 1164.2 775.0 943.2 606.1 841.6 1016.0 1037.0 1106.9 823.2 962.6 964.4 136.7 0.0 8.2 444.0 66.1 935.2 12.3 18.3 67.7 81.7 86.7 565.8 2.2 450.4 5.2 228.1 41.7 46.3 6.0 2.2 682.9 1.8 73.6 33.8 936.6 140.2 0.0 331.6 1.1 0.7 43.8 860.7 3.6 22.9 174.4 103.6 208.9 9363.4 6072.6 38.7 2.1 0.6 4.1 718.0 292.6 355.3 2629.4 940.6 2481.3 60.9 70.3 9454.8 0.0 12.1 2.2 0.6 0.3 4958.2 7.2 15.0 0.2 8155.9 1.0 311.4 223.5 2958.4 345.5 14.8 12.8 15.1 1684.9 74.3 60.6 7201.0 1.7 4.7 BLM "BS, RECQ2, RECQL3" ENSG00000197299 "BLM RecQ like helicase" P54132 15 90717346-90816166 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.7;lymphoid tissue: 7.9;salivary gland: 7.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 18.3;Oligodendrocyte precursor cells: 58.3;Plasma cells: 20.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005689 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA005689: AB_1845372" "unprognostic (2.77e-1)" "unprognostic (3.82e-3)" "unprognostic (4.03e-2)" "unprognostic (2.98e-2)" "unprognostic (4.75e-2)" "unprognostic (9.89e-2)" "unprognostic (6.12e-5)" "unprognostic (2.82e-2)" "unprognostic (4.55e-3)" "unprognostic (5.24e-3)" "unprognostic (1.80e-3)" "unprognostic (9.12e-2)" "unprognostic (1.55e-15)" "unprognostic (6.53e-3)" "unprognostic (6.55e-2)" "unprognostic (2.43e-1)" "unprognostic (1.83e-2)" 0.3 0.2 0.9 3.6 1.1 5.7 0.5 2.3 0.9 0.1 0.3 1.4 1.0 0.4 0.4 0.6 0.3 0.3 0.3 0.8 1.1 0.1 0.1 0.4 6.4 1.2 1.4 0.1 0.2 0.0 0.6 1.2 1.1 0.1 1.7 2.4 7.8 0.0 0.5 0.4 1.6 0.4 1.0 1.6 1.1 2.2 0.9 7.9 0.3 0.1 6.2 1.0 0.2 1.0 13.0 14.4 20.4 12.6 0.1 0.9 14.6 9.4 3.2 11.1 13.4 11.7 10.1 35.1 5.9 2.6 14.1 20.4 25.7 7.1 15.1 19.1 20.5 36.4 14.8 3.9 0.0 33.7 17.3 0.3 0.1 10.6 4.7 1.3 7.9 16.9 32.7 9.9 11.0 7.4 28.3 14.5 22.2 24.9 4.2 25.4 39.1 14.7 2.3 18.9 14.6 14.7 8.5 11.5 4.8 18.1 7.2 23.4 3.7 8.6 13.6 9.6 21.0 6.4 30.4 39.5 5.6 25.8 15.7 1.7 0.6 2.6 1.6 0.8 2.6 4.6 1.4 2.1 0.7 2.3 1.0 1.1 0.7 3.1 1.0 0.7 3.2 0.9 0.9 1.1 2.3 0.9 0.8 1.1 1.2 1.4 1.1 1.0 0.9 1.0 0.9 3.2 8.9 1.0 12.9 0.3 0.5 0.5 0.6 3.6 1.3 1.0 7.9 0.0 4.2 0.0 2.1 5.5 6.9 2.2 1.9 1.0 2.7 1.3 1.3 2.0 0.0 18.3 0.7 0.7 6.8 1.8 3.6 1.7 13.3 8.1 2.2 0.6 5.7 0.0 8.6 1.3 0.0 7.7 1.3 1.6 0.0 7.7 0.0 7.5 2.7 1.7 10.3 58.3 2.6 1.2 0.3 0.4 20.6 0.7 0.2 0.0 5.4 7.1 0.0 0.9 1.7 17.1 12.9 2.2 0.6 1.0 10.2 0.7 4.0 0.4 CD14 ENSG00000170458 "CD14 molecule" P08571 5 140631728-140633701 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 403.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 2809.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3697.0" "Group enriched" "Detected in all" 5 "granulocytes: 942.3;monocytes: 3697.0" "Cell line enhanced" "Detected in many" "A549: 10.1;CACO-2: 17.0;SiHa: 21.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001887, HPA002127, CAB033631, CAB072865, CAB072866" Enhanced Approved Vesicles "Secreted to blood" NA NA 2750000000 10000000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" Vesicles "CAB033631: AB_781932, CAB072865: AB_2665714, CAB072866: AB_2665715, HPA001887: AB_1078442, HPA002127: AB_1078440" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (3.42e-3)" "unprognostic (3.89e-2)" "unprognostic (3.29e-2)" "unprognostic (1.54e-1)" "unprognostic (4.71e-3)" "unprognostic (4.88e-2)" "unprognostic (2.16e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.80e-5)" "unprognostic (1.20e-2)" "unprognostic (6.87e-3)" "unprognostic (8.12e-2)" "unprognostic (6.92e-2)" 134.5 151.3 15.9 236.1 16.0 68.8 50.5 14.7 33.1 27.9 26.8 55.9 31.4 23.5 21.0 23.9 40.5 79.8 35.6 14.5 23.2 41.6 403.4 91.6 107.9 33.6 26.4 21.4 27.0 16.7 35.5 183.0 29.6 18.3 47.6 4.0 121.8 30.4 10.6 13.5 38.0 111.7 25.4 87.6 33.9 26.6 30.3 20.9 23.0 17.5 23.0 102.5 12.6 42.1 0.1 10.1 0.1 0.8 1.3 0.3 0.5 0.9 4.7 1.9 2.1 17.0 3.1 0.4 1.0 5.9 1.4 4.9 0.0 2.6 0.5 0.1 1.4 0.3 1.1 2.0 5.1 1.1 0.3 4.8 0.3 0.3 1.5 0.4 0.0 0.3 0.3 0.3 1.7 0.3 0.1 1.2 0.4 0.3 0.3 0.4 0.6 1.8 0.2 0.1 3.6 1.3 21.1 0.5 0.5 0.2 0.3 2.1 0.6 0.4 0.4 1.9 2.1 0.8 1.6 0.8 0.4 0.5 0.1 13.5 3697.0 21.7 6.8 677.3 8.7 12.1 3.7 3.9 440.4 1.9 5.2 3.6 942.3 3.8 95.1 25.2 3.7 3034.0 15.9 16.0 14.7 33.1 14.5 23.2 33.6 26.4 29.6 25.4 30.3 42.1 17.9 9.6 27.6 0.7 9.0 5.1 3.4 5.2 6.2 7.2 164.9 23.4 2.6 22.8 18.3 1.8 0.0 18.1 5.3 77.2 1.9 5.1 2.3 0.6 1.7 46.5 7.2 29.5 0.7 1.8 16.3 19.7 1.1 1.0 8.8 0.6 340.2 348.0 2809.2 33.7 0.9 5.9 4.1 668.4 75.9 6.1 5.0 652.8 8.8 23.4 285.3 30.0 11.3 0.5 0.4 1.8 35.3 5.3 1.8 1.7 5.0 7.0 9.8 5.1 32.9 25.8 9.7 1.5 2.0 4.4 4.3 46.1 5.5 2.1 7.4 4.9 CD33 "FLJ00391, p67, SIGLEC-3, SIGLEC3" ENSG00000105383 "CD33 molecule" P20138 19 51225064-51243860 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.4;lymphoid tissue: 23.9" "Group enriched" "Detected in some" 6 "granulocytes: 76.0;Hofbauer cells: 78.8;Kupffer cells: 131.2;Langerhans cells: 41.4;Macrophages: 53.5;monocytes: 65.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 166.5;intermediate monocyte: 122.0;myeloid DC: 213.5;non-classical monocyte: 57.8" "Group enriched" "Detected in many" 9 "dendritic cells: 213.5;monocytes: 166.5" "Cell line enhanced" "Detected in some" "HEL: 86.1;HL-60: 115.6;HMC-1: 82.4;NB-4: 55.2;RPMI-8226: 62.5;THP-1: 67.0;U-937: 84.1" "CAB011442, HPA035832, HPA064807, CAB079996" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 3400000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Plasma membrane" "CAB011442: , CAB079996: , HPA035832: AB_2674808, HPA064807: AB_2685356" "unprognostic (1.18e-2)" "unprognostic (1.45e-2)" "unprognostic (2.80e-2)" "unprognostic (7.14e-2)" "unprognostic (3.71e-1)" "unprognostic (9.43e-2)" "unprognostic (2.59e-1)" "unprognostic (5.90e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-1)" "unprognostic (2.53e-1)" "unprognostic (6.28e-2)" "unprognostic (6.88e-4)" "unprognostic (7.79e-2)" "unprognostic (3.35e-2)" "unprognostic (6.49e-2)" "unprognostic (1.67e-1)" 7.9 3.4 1.1 11.2 1.2 32.4 2.5 1.5 1.6 3.0 2.5 3.2 3.3 1.7 1.3 2.0 2.5 6.6 2.0 1.1 1.8 1.4 5.5 12.6 10.1 2.5 1.6 1.4 1.4 1.2 0.9 6.9 2.4 1.4 4.2 0.2 1.8 2.6 0.9 2.7 4.4 7.1 1.9 23.9 2.3 1.0 2.3 3.5 0.9 0.8 3.5 6.2 1.3 3.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.2 0.0 5.5 0.4 0.0 1.3 0.3 0.0 0.2 0.0 0.1 0.1 86.1 0.3 0.0 0.0 115.6 82.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 16.2 21.2 0.2 0.0 0.0 55.2 0.2 0.0 25.9 0.0 4.4 62.5 0.4 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 67.0 0.7 14.0 1.1 1.8 0.1 0.3 7.6 0.2 9.6 84.1 0.4 17.9 166.5 11.0 0.3 122.0 0.4 0.1 0.2 0.5 213.5 0.4 0.3 0.2 20.5 15.5 57.8 6.3 1.1 77.8 1.1 1.2 1.5 1.6 1.1 1.8 2.5 1.6 2.4 1.9 2.3 3.6 0.7 0.0 6.7 0.0 1.0 1.8 0.5 0.0 0.0 0.2 1.4 0.4 0.8 0.0 0.6 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.7 0.1 0.1 3.0 0.0 4.2 0.0 0.0 0.5 1.1 0.0 0.1 76.0 0.1 5.3 0.7 78.8 0.0 0.0 0.0 0.0 131.2 41.4 1.7 0.3 53.5 1.8 11.2 65.0 0.2 1.0 0.5 0.2 0.0 0.0 0.0 0.3 0.4 0.0 0.2 0.7 0.6 0.0 1.1 0.3 0.7 0.5 0.0 1.0 0.8 2.5 0.1 0.0 0.4 CD53 "MOX44, TSPAN25" ENSG00000143119 "CD53 molecule" P19397 1 110871188-110899922 "CD markers, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 448.3" "Cell type enhanced" "Detected in many" "B-cells: 310.0;dendritic cells: 375.0;Hofbauer cells: 365.7;Kupffer cells: 324.3;Macrophages: 294.8;NK-cells: 383.1;T-cells: 297.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 473.5;HDLM-2: 214.8;HMC-1: 298.4;Karpas-707: 188.1;U-266/70: 251.2;U-698: 149.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047216 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "HPA047216: AB_2679986" "unprognostic (2.93e-2)" "unprognostic (1.25e-2)" "unprognostic (7.45e-3)" "unprognostic (1.02e-3)" "unprognostic (8.88e-2)" "unprognostic (3.78e-2)" "unprognostic (2.96e-1)" "unprognostic (6.07e-2)" "unprognostic (2.83e-2)" "unprognostic (2.03e-1)" "unprognostic (5.09e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.60e-4)" "unprognostic (9.58e-2)" "unprognostic (4.95e-2)" "unprognostic (1.33e-1)" "unprognostic (7.72e-2)" 63.4 30.8 10.1 284.4 11.1 126.6 27.0 12.6 16.3 20.8 12.3 41.5 37.9 17.3 10.5 20.0 22.8 58.5 12.2 9.7 13.4 15.1 46.8 114.9 397.9 18.9 16.0 9.2 11.9 6.6 6.2 58.5 18.9 12.8 54.8 2.0 19.3 12.8 4.5 6.7 103.4 55.8 18.3 269.4 44.3 5.7 17.5 144.9 11.3 10.6 448.3 85.1 9.0 31.9 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 473.5 0.2 0.0 0.2 0.5 0.0 0.0 0.0 214.8 0.0 26.4 0.1 0.0 0.0 60.4 298.4 0.0 0.0 0.0 0.0 0.0 0.0 139.2 11.2 188.1 0.0 0.0 103.1 71.1 0.4 0.0 0.0 98.0 0.7 104.2 0.0 0.0 0.0 0.1 0.0 0.2 0.2 1.5 0.0 88.4 17.2 0.2 0.4 0.1 0.5 251.2 123.2 149.2 1.5 68.7 3.4 1483.0 779.5 479.0 732.4 808.6 658.1 794.0 527.8 649.2 631.9 745.1 377.9 552.5 1144.2 526.6 882.9 517.5 740.3 1621.0 10.1 11.1 12.6 16.3 9.7 13.4 18.9 16.0 18.9 18.3 17.5 31.9 4.2 16.0 24.4 0.7 310.0 7.0 0.6 0.0 0.6 0.0 2.3 5.1 1.0 5.7 8.6 1.8 0.0 2.1 375.0 0.2 0.0 0.5 0.4 0.4 0.5 13.0 0.0 42.9 5.8 0.2 5.4 6.7 7.1 0.6 162.2 0.0 16.4 6.7 365.7 0.0 1.4 0.3 0.0 324.3 161.5 1.9 2.1 294.8 39.2 69.3 156.3 0.1 383.1 1.0 0.6 0.3 0.1 0.4 134.0 0.3 0.0 1.6 4.4 0.6 6.6 1.9 1.8 0.1 0.6 1.1 5.5 4.1 297.0 0.0 0.2 0.3 CD86 "B7-2, B7.2, CD28LG2" ENSG00000114013 "CD86 molecule" P42081 3 122055362-122121139 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 34.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 121.3;Kupffer cells: 107.8;Langerhans cells: 148.3;Macrophages: 151.8;Microglial cells: 78.7;monocytes: 489.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 79.9;intermediate monocyte: 79.0;memory B-cell: 41.0;myeloid DC: 78.8;naive B-cell: 28.5;non-classical monocyte: 85.2" "Group enriched" "Detected in many" 18 "B-cells: 41.0;dendritic cells: 78.8;monocytes: 85.2" "Cell line enriched" "Detected in some" 7 "HDLM-2: 296.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004319, HPA026802" Approved Supported "Plasma membrane,Centriolar satellite" NA NA 160000 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "Centriolar satellite" "CAB004319: AB_627200, HPA026802: " "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (3.04e-2)" "unprognostic (3.52e-2)" "unprognostic (1.36e-1)" "unprognostic (2.79e-1)" "unprognostic (1.15e-1)" "unprognostic (8.56e-2)" "unprognostic (7.72e-3)" "unprognostic (1.21e-1)" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (9.72e-2)" "unprognostic (1.70e-2)" "unprognostic (9.78e-2)" "unprognostic (8.67e-2)" 7.8 5.3 3.5 34.5 3.4 10.3 4.4 4.0 3.6 3.5 4.8 6.3 3.7 2.4 1.0 4.0 2.1 14.3 2.7 3.2 6.1 1.9 11.2 18.6 28.8 7.2 5.5 2.1 2.6 2.9 1.1 15.0 7.0 2.4 7.7 0.9 2.3 2.5 0.8 2.0 6.8 7.4 5.3 23.4 5.2 3.1 5.0 10.6 1.3 0.8 22.0 14.9 1.0 10.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 40.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 296.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.5 0.2 0.0 0.0 0.2 0.0 32.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.4 0.0 0.1 0.0 0.1 15.1 0.6 35.1 0.0 0.9 0.0 0.1 79.9 0.8 0.0 79.0 0.0 41.0 0.2 0.3 78.8 28.5 0.2 0.1 0.9 3.7 85.2 8.3 1.6 33.4 3.5 3.4 4.0 3.6 3.2 6.1 7.2 5.5 7.0 5.3 5.0 10.2 0.9 0.0 7.7 0.3 36.5 3.6 0.1 1.3 0.0 0.0 0.4 1.3 0.3 1.5 3.2 1.8 0.0 1.8 3.3 0.0 0.0 0.2 3.7 0.1 0.0 2.6 0.0 1.3 0.2 3.5 0.8 0.8 0.5 0.0 2.5 0.1 1.8 0.8 121.3 0.0 0.3 0.0 0.0 107.8 148.3 2.7 0.0 151.8 7.2 78.7 489.4 0.0 0.0 0.5 0.1 0.3 0.0 0.0 20.6 0.3 0.0 0.1 0.1 0.4 0.0 0.3 0.7 0.2 0.3 0.2 4.0 1.9 2.1 0.1 0.0 0.3 CEACAM4 CGM7 ENSG00000105352 "CEA cell adhesion molecule 4" O75871 19 41618971-41627074 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 21.3;lymphoid tissue: 32.6" "Cell type enhanced" "Detected in some" "Kupffer cells: 41.1;Macrophages: 20.9;monocytes: 9.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "neutrophil: 122.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 122.7" "Cell line enriched" "Detected in single" 6 "U-937: 4.1" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (1.10e-2)" "unprognostic (1.52e-2)" "unprognostic (1.24e-1)" "unprognostic (4.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.83e-2)" "unprognostic (9.11e-2)" "unprognostic (5.59e-2)" "unprognostic (1.79e-2)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (2.17e-1)" "unprognostic (2.09e-9)" "unprognostic (3.65e-2)" "unprognostic (2.95e-2)" "unprognostic (1.47e-1)" "unprognostic (4.34e-1)" 2.1 0.5 0.1 4.8 0.1 21.3 0.5 0.1 0.2 0.4 0.2 0.7 0.3 0.3 0.8 1.0 1.0 1.0 0.8 0.1 0.1 0.8 1.0 5.7 0.9 0.2 0.2 0.2 1.2 0.0 0.3 0.3 0.2 1.1 0.2 0.0 0.8 0.0 0.2 0.3 1.8 1.0 0.1 32.6 0.8 0.1 0.2 0.3 0.4 0.6 0.6 0.7 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 30.1 5.6 0.0 23.1 0.1 0.7 1.2 0.0 23.3 0.0 0.7 0.0 122.7 0.0 9.9 0.2 11.3 12.1 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.2 0.1 0.2 0.2 0.1 0.0 3.9 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 3.1 0.0 0.0 0.0 0.0 41.1 1.6 0.2 0.0 20.9 1.8 1.9 9.2 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 CLEC4E "CLECSF9, mincle" ENSG00000166523 "C-type lectin domain family 4 member E" Q9ULY5 12 8533305-8540905 "Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 75.7;lymphoid tissue: 52.3" "Cell type enhanced" "Detected in some" "Glandular and luminal cells: 31.9;Kupffer cells: 158.0;Macrophages: 115.2;monocytes: 109.5" "Cancer enhanced" "Detected in many" "testis cancer: 6.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 16 "classical monocyte: 128.8;neutrophil: 448.8" "Group enriched" "Detected in many" 17 "granulocytes: 448.8;monocytes: 128.8" "Group enriched" "Detected in some" 4 "NB-4: 4.3;RPTEC TERT1: 12.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA004935 Uncertain Uncertain Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 41: Macrophages - Immune response" Cytosol "HPA004935: AB_2667299" "unprognostic (3.05e-2)" "unprognostic (2.01e-2)" "unprognostic (8.91e-2)" "unprognostic (3.76e-1)" "unprognostic (1.76e-1)" "unprognostic (9.71e-3)" "unprognostic (1.77e-1)" "unprognostic (1.24e-1)" "unprognostic (9.29e-2)" "unprognostic (1.83e-1)" "unprognostic (1.16e-1)" "unprognostic (2.11e-2)" "unprognostic (7.65e-3)" "unprognostic (1.62e-1)" "unprognostic (1.51e-1)" "unprognostic (8.44e-2)" "unprognostic (2.29e-1)" 13.3 5.4 2.3 37.5 2.1 75.7 4.5 1.8 4.4 5.8 2.2 2.2 0.4 2.3 0.4 3.2 5.5 11.8 2.5 2.3 2.9 3.6 6.6 22.4 7.6 1.3 1.3 1.7 6.2 1.7 1.9 2.1 1.2 2.3 1.0 1.3 1.4 1.2 0.7 0.9 3.1 5.7 0.7 52.3 2.5 1.1 2.0 2.2 10.5 5.0 2.3 9.6 1.7 2.9 0.1 0.4 0.4 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.1 1.5 0.1 0.1 2.0 0.0 0.1 0.1 0.2 0.2 0.1 0.3 0.2 0.2 0.1 0.5 0.1 0.0 1.5 0.0 0.5 0.2 0.2 0.2 0.2 0.0 0.1 0.0 4.3 0.3 0.0 0.0 0.0 0.2 0.1 12.4 0.1 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.4 1.0 0.5 0.1 1.0 0.1 0.2 0.1 0.1 1.3 0.4 0.1 0.2 128.8 0.5 0.1 18.1 0.3 0.1 0.1 0.1 16.9 0.1 0.0 0.1 448.8 0.0 0.7 0.7 0.0 30.3 2.3 2.1 1.8 4.4 2.3 2.9 1.3 1.3 1.2 0.7 2.0 2.9 6.2 0.0 4.7 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 5.7 1.8 1.8 0.0 0.0 0.3 0.0 0.0 9.0 0.3 2.1 4.4 3.5 0.0 0.0 0.0 0.0 0.1 1.4 0.0 31.9 0.0 0.0 7.1 2.1 5.6 0.0 0.0 0.0 0.0 158.0 9.0 2.9 0.9 115.2 0.0 0.0 109.5 0.0 4.1 0.0 0.0 0.4 0.0 0.4 1.3 0.0 0.0 0.2 0.7 0.0 13.1 0.2 0.4 0.2 0.5 0.1 0.0 0.1 1.1 0.0 0.0 0.1 CLEC7A "CD369, CLECSF12, dectin-1, hDectin-1, SCARE2" ENSG00000172243 "C-type lectin domain containing 7A" Q9BXN2 12 10116777-10130258 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 84.0;lung: 30.9;lymphoid tissue: 44.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 87.2;Kupffer cells: 415.2;Langerhans cells: 291.5;Macrophages: 255.5;monocytes: 186.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 249.6" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 16 "Karpas-707: 192.2;U-266/84: 168.1" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (1.79e-1)" "unprognostic (1.88e-2)" "unprognostic (2.98e-2)" "unprognostic (3.64e-1)" "unprognostic (3.03e-2)" "unprognostic (5.49e-2)" "unprognostic (5.19e-2)" "unprognostic (5.88e-3)" "unprognostic (2.10e-1)" "unprognostic (9.87e-2)" "unprognostic (7.46e-2)" "unprognostic (4.40e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (1.83e-2)" "unprognostic (3.89e-2)" "unprognostic (5.13e-2)" "unprognostic (1.14e-1)" 9.9 5.9 2.2 44.5 2.0 84.0 4.5 2.6 3.7 3.5 3.3 7.5 5.6 3.2 3.7 9.7 5.8 11.1 5.7 1.9 3.3 3.5 11.0 30.9 14.4 5.0 2.7 2.4 2.9 2.0 2.7 7.3 4.0 3.3 7.3 1.7 7.3 3.2 1.3 3.8 8.6 8.7 3.6 34.2 4.6 1.5 3.8 10.0 2.6 2.0 11.9 9.1 4.8 6.1 0.3 0.4 0.1 0.2 0.0 0.0 1.1 0.0 0.5 0.2 0.1 0.1 0.4 0.1 0.1 0.0 1.1 0.6 0.0 0.0 0.0 0.1 0.0 0.4 0.5 0.0 0.0 0.9 0.7 0.1 0.8 0.1 0.0 0.2 0.1 0.2 0.0 192.2 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.1 4.3 0.0 5.2 0.3 0.2 0.3 0.6 0.0 1.4 0.4 0.1 0.3 0.1 0.2 0.2 0.2 11.4 168.1 0.1 0.3 1.0 0.2 1.4 122.9 2.2 0.3 137.2 0.5 0.3 0.3 0.2 60.6 0.3 0.3 0.2 249.6 0.4 148.1 1.0 0.4 40.4 2.2 2.0 2.6 3.7 1.9 3.3 5.0 2.7 4.0 3.6 3.8 6.1 2.0 12.8 15.1 0.3 5.9 3.7 0.2 0.9 8.6 0.0 3.1 2.8 0.9 0.0 9.7 0.0 0.0 1.5 2.1 0.2 0.0 0.1 1.7 0.2 0.1 9.3 0.0 0.0 0.1 0.0 14.1 2.4 0.0 0.1 6.3 0.0 6.1 2.1 87.2 0.0 0.1 0.0 4.1 415.2 291.5 2.2 0.3 255.5 3.6 27.2 186.1 0.0 8.2 0.0 0.0 0.0 1.1 0.0 1.1 0.1 0.0 1.3 2.4 0.4 13.1 1.1 1.0 0.1 0.5 13.2 3.0 5.3 4.1 0.0 0.0 0.5 CPM ENSG00000135678 "Carboxypeptidase M" P14384 12 68842197-68971570 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 156.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 359.0;Alveolar cells type 2: 362.2;Kupffer cells: 368.5;Sertoli cells: 762.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 21.0;intermediate monocyte: 14.5;myeloid DC: 16.6;non-classical monocyte: 7.4" "Group enriched" "Detected in many" 5 "dendritic cells: 16.6;monocytes: 21.0" "Group enriched" "Detected in many" 4 "ASC diff: 71.1;ASC TERT1: 50.0;HSkMC: 91.2;SiHa: 68.9;THP-1: 26.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002657, HPA077243" Enhanced Uncertain Vesicles NA NA 7100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA002657: AB_1078398, HPA077243: " "unprognostic (1.74e-1)" "unprognostic (3.11e-1)" "unprognostic (2.88e-3)" "prognostic favorable (1.00e-4)" "unprognostic (4.58e-2)" "unprognostic (8.61e-2)" "unprognostic (1.57e-2)" "unprognostic (2.01e-1)" "unprognostic (8.42e-2)" "unprognostic (1.40e-1)" "unprognostic (1.35e-1)" "unprognostic (1.42e-1)" "unprognostic (1.47e-3)" "unprognostic (8.58e-2)" "unprognostic (6.85e-2)" "unprognostic (2.59e-2)" "unprognostic (1.06e-1)" 156.1 11.5 6.4 14.4 13.3 3.5 40.2 10.1 10.5 14.4 3.8 33.5 4.4 23.9 0.9 10.1 16.2 16.1 4.6 7.6 10.2 41.3 26.5 59.3 16.1 19.3 11.5 18.0 13.0 12.0 1.0 70.1 11.9 14.7 26.6 6.7 4.1 2.8 5.8 21.7 5.9 6.4 7.5 19.4 15.3 5.4 28.0 4.3 7.5 9.7 10.5 9.3 5.7 23.5 0.1 4.0 0.1 0.0 71.1 50.0 0.7 9.8 1.1 1.7 2.3 3.2 4.1 0.5 9.6 1.4 4.1 0.0 1.4 2.7 4.1 0.1 2.7 0.0 15.1 0.3 0.4 1.2 1.9 91.2 0.6 1.0 2.0 8.6 0.0 0.3 0.0 0.1 7.3 1.7 0.0 0.7 1.7 0.0 5.2 3.1 0.6 0.0 7.2 5.9 0.4 0.2 68.9 10.7 7.9 5.5 1.2 26.5 0.2 1.2 7.5 0.5 0.2 0.4 0.5 13.1 4.3 13.1 5.9 0.6 21.0 0.1 0.2 14.5 0.0 1.8 1.5 0.1 16.6 3.5 0.9 0.2 1.6 0.5 7.4 1.1 1.9 7.3 6.4 13.3 10.1 10.5 7.6 10.2 19.3 11.5 11.9 7.5 28.0 23.5 83.3 359.0 362.2 34.6 4.9 12.4 3.5 6.1 0.6 3.3 7.8 8.9 2.6 135.8 70.1 51.5 0.0 32.3 1.1 97.5 29.4 57.9 16.6 100.9 8.3 29.0 10.8 3.6 1.2 212.5 59.9 14.1 4.6 237.1 112.5 6.7 73.9 36.6 134.6 0.0 1.3 28.7 0.0 368.5 36.3 17.5 105.0 202.2 10.6 19.7 23.3 68.9 1.0 23.1 161.8 68.0 65.9 79.0 2.4 38.7 1.9 63.7 16.4 5.7 762.6 7.2 126.9 0.6 3.9 2.4 9.9 172.4 14.5 46.3 32.7 2.8 CSF1R "C-FMS, CD115, CSFR, FMS" ENSG00000182578 "Colony stimulating factor 1 receptor" P07333 5 150053291-150113372 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 113.3;placenta: 103.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 103.2;Hofbauer cells: 340.4;Kupffer cells: 291.2;Langerhans cells: 73.4;Macrophages: 196.3;Microglial cells: 134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 444.6;non-classical monocyte: 646.9" "Lineage enriched" "Detected in many" 5 "monocytes: 646.9" "Group enriched" "Detected in some" 4 "BEWO: 123.0;SK-BR-3: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008970, HPA012323" Uncertain Supported "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 1600000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Plasma membrane" "CAB008970: , HPA012323: AB_1848977" "unprognostic (3.82e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-3)" "unprognostic (9.83e-2)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (9.37e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (3.67e-2)" "prognostic unfavorable (4.92e-4)" "unprognostic (1.72e-2)" "unprognostic (4.61e-2)" 51.3 31.0 19.6 75.1 17.1 5.6 19.3 20.2 21.4 21.6 19.3 21.9 24.3 12.1 5.8 21.0 17.2 40.6 16.6 19.8 33.8 7.1 27.5 36.6 54.4 41.4 35.5 12.7 9.9 11.8 5.7 103.3 40.1 9.1 21.5 1.5 10.1 20.8 3.2 13.4 37.3 41.9 36.6 113.3 21.0 7.0 40.6 14.3 6.0 11.8 21.7 42.6 3.8 67.6 4.5 0.2 0.0 0.0 1.9 0.4 123.0 0.2 0.2 0.0 0.0 3.8 0.0 5.9 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.2 1.1 3.0 0.0 6.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 6.1 0.1 0.0 0.0 0.0 1.9 0.6 0.0 0.0 0.2 0.2 0.0 47.8 0.0 1.9 0.0 20.7 0.0 0.8 0.2 0.1 3.3 0.0 0.3 0.1 6.6 2.6 0.0 3.0 138.4 4.0 0.6 444.6 0.6 0.3 0.2 0.4 139.0 0.2 0.3 0.2 21.6 0.2 646.9 11.1 0.5 132.7 19.6 17.1 20.2 21.4 19.8 33.8 41.4 35.5 40.1 36.6 40.6 67.6 2.0 0.0 3.8 0.0 4.3 2.8 0.0 0.0 1.2 0.0 0.5 2.3 3.1 4.3 0.0 0.0 0.0 6.2 2.8 0.0 0.0 0.0 4.8 0.0 0.1 10.5 0.0 2.5 0.4 0.0 103.2 2.2 1.5 0.2 2.5 8.3 2.9 1.5 340.4 0.0 0.5 0.3 0.0 291.2 73.4 5.4 1.8 196.3 3.6 134.9 39.4 0.0 1.0 1.5 0.3 0.1 1.7 0.0 1.0 0.0 0.0 0.1 0.7 0.5 13.1 1.2 2.0 2.2 0.2 0.4 1.3 26.4 1.3 2.2 0.2 0.0 CSF2RA "alphaGMR, CD116, CSF2R" ENSG00000198223 "Colony stimulating factor 2 receptor subunit alpha" P15509 X 1268800-1310381 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 64.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 248.5;Extravillous trophoblasts: 124.6;Langerhans cells: 365.1;Macrophages: 114.5;monocytes: 575.2;Syncytiotrophoblasts: 312.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 320.2" "Group enriched" "Detected in all" 30 "dendritic cells: 170.7;granulocytes: 320.2;monocytes: 161.1" "Group enriched" "Detected in some" 7 "BEWO: 194.0;HMC-1: 58.3;SK-MEL-30: 142.0" "Low region specificity" "Detected in single" CAB016148 Uncertain "Secreted to blood" NA NA 13000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 3: Monocytes - Immune response regulation" "CAB016148: AB_626868" "unprognostic (4.19e-2)" "prognostic favorable (2.38e-5)" "unprognostic (5.47e-2)" "unprognostic (4.33e-2)" "unprognostic (4.88e-2)" "prognostic favorable (2.81e-4)" "unprognostic (8.24e-2)" "unprognostic (2.17e-1)" "unprognostic (5.55e-2)" "unprognostic (8.48e-2)" "unprognostic (8.89e-2)" "unprognostic (3.80e-1)" "unprognostic (2.89e-2)" "unprognostic (8.91e-3)" "prognostic unfavorable (5.53e-4)" "unprognostic (3.60e-1)" "unprognostic (9.44e-2)" 10.0 5.5 4.2 25.4 4.4 21.7 6.8 5.2 4.8 5.1 5.4 5.8 5.8 2.5 1.7 5.3 4.1 12.6 2.5 4.0 5.4 2.3 4.6 14.2 20.9 8.5 6.6 1.8 3.3 3.1 1.4 64.4 8.3 2.5 7.4 0.7 3.0 3.0 0.6 4.0 6.6 7.1 7.2 14.9 5.0 1.1 9.0 9.4 1.6 2.0 23.5 12.7 1.5 11.9 0.3 11.5 0.5 0.0 0.0 0.0 194.0 0.3 0.5 0.4 0.1 4.2 1.0 0.2 12.6 0.0 10.3 0.2 0.1 0.0 0.0 3.9 0.1 0.2 8.0 0.1 0.0 4.6 58.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.0 0.2 0.4 18.8 1.6 1.8 0.4 0.2 0.5 0.3 0.0 0.5 0.1 0.3 3.7 0.1 142.0 15.1 9.4 16.8 0.0 0.2 5.5 0.1 0.0 0.1 0.1 0.6 0.0 18.5 0.1 17.4 161.1 200.3 0.4 94.9 1.0 2.3 0.3 0.3 170.7 0.6 0.4 0.3 320.2 7.3 48.7 164.0 1.1 65.5 4.2 4.4 5.2 4.8 4.0 5.4 8.5 6.6 8.3 7.2 9.0 11.9 1.2 0.0 7.3 1.3 5.5 7.8 0.9 0.1 0.6 0.6 6.3 2.5 1.2 2.8 3.6 1.8 0.0 248.5 38.3 0.0 0.0 0.3 0.6 7.8 1.2 5.3 0.0 1.3 1.4 1.8 124.6 3.4 0.0 14.7 10.1 0.5 0.7 0.1 75.5 0.0 1.7 0.0 2.0 74.8 365.1 0.3 0.9 114.5 8.8 66.5 575.2 0.3 0.0 1.5 0.9 0.2 0.0 0.4 1.0 0.5 0.0 0.1 2.7 1.5 6.6 1.8 1.4 0.2 0.4 0.0 5.3 312.5 3.3 0.1 0.0 2.5 CTSL "CTSL1, FLJ31037" ENSG00000135047 "Cathepsin L" P07711 9 87724051-87731469 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 563.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1081.6;Extravillous trophoblasts: 1012.3;Hepatic stellate cells: 580.4;Hofbauer cells: 1105.7;Macrophages: 537.2;Syncytiotrophoblasts: 1543.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 128.1;non-classical monocyte: 195.2" "Lineage enriched" "Detected in many" 12 "monocytes: 195.2" "Cell line enhanced" "Detected in many" "ASC TERT1: 2305.0;HSkMC: 1061.0" "Low region specificity" "Detected in all" "CAB000459, HPA070413" Enhanced Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 17000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "CAB000459: AB_2292484, HPA070413: " "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" "unprognostic (1.24e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.73e-4)" "unprognostic (1.19e-3)" "unprognostic (8.12e-3)" "prognostic unfavorable (5.15e-5)" "unprognostic (2.09e-1)" "unprognostic (3.15e-1)" "unprognostic (6.80e-2)" "unprognostic (3.21e-1)" "prognostic favorable (4.34e-4)" "unprognostic (5.64e-3)" "unprognostic (2.26e-2)" "unprognostic (1.72e-1)" "unprognostic (7.11e-3)" 232.4 86.6 49.2 136.0 55.4 84.8 110.0 52.9 67.5 69.5 67.9 110.3 39.7 108.1 81.6 33.3 108.4 85.0 112.5 47.0 52.3 207.3 333.5 154.9 101.1 54.4 54.0 96.4 61.9 151.1 69.5 563.6 57.5 68.2 58.8 32.3 77.6 91.7 71.9 39.8 57.1 125.2 52.4 124.4 71.4 80.1 112.2 33.0 76.1 79.8 49.4 209.8 48.0 59.6 88.1 423.0 32.6 55.3 514.0 2305.0 198.4 267.2 781.8 232.2 300.6 43.0 86.3 0.0 128.9 355.4 754.0 67.5 49.8 86.0 198.4 1.9 37.8 18.1 111.2 105.1 352.6 0.1 51.4 1061.0 138.9 373.7 134.9 186.6 194.9 0.0 162.5 0.7 326.6 115.6 0.5 9.9 67.7 128.6 77.5 21.6 21.5 0.6 158.6 39.0 42.8 50.6 62.1 133.5 312.3 177.9 14.5 97.9 296.9 190.8 104.7 750.6 125.9 18.5 84.1 0.9 692.6 0.2 67.9 0.3 13.5 0.6 0.3 128.1 0.0 0.0 6.6 0.1 7.9 0.1 16.7 1.3 0.5 0.2 195.2 0.3 1.7 10.1 49.2 55.4 52.9 67.5 47.0 52.3 54.4 54.0 57.5 52.4 112.2 59.6 86.1 41.7 52.9 15.3 11.2 37.7 82.1 58.0 15.4 43.8 12.2 33.4 96.8 87.2 46.4 75.4 18.8 1081.6 0.3 16.3 27.4 91.8 5.3 48.1 119.9 110.0 11.5 251.2 18.6 93.4 1012.3 261.7 10.2 27.6 29.7 63.6 580.4 122.6 1105.7 13.5 24.0 8.5 20.3 206.9 105.4 17.4 156.9 537.2 64.0 14.0 16.2 79.5 0.0 17.6 31.7 67.2 5.6 187.3 1.9 34.5 8.0 138.3 67.3 45.4 92.1 176.9 136.3 207.4 60.5 6.8 34.0 1543.6 10.8 30.8 11.7 44.8 CYBB "CGD, GP91-PHOX, NOX2" ENSG00000165168 "Cytochrome b-245 beta chain" P04839 X 37780059-37813461 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 160.9;lymphoid tissue: 158.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 157.2;Kupffer cells: 456.0;Macrophages: 469.3;monocytes: 396.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 276.3;intermediate monocyte: 261.6" "Group enriched" "Detected in many" 4 "dendritic cells: 90.9;granulocytes: 110.5;monocytes: 276.3" "Group enriched" "Detected in some" 5 "Daudi: 52.8;NB-4: 64.2;REH: 54.6;RPMI-8226: 210.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051227 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA051227: AB_2681395" "unprognostic (5.83e-2)" "unprognostic (1.77e-2)" "unprognostic (2.15e-3)" "unprognostic (1.48e-2)" "unprognostic (1.27e-1)" "unprognostic (5.65e-2)" "unprognostic (2.29e-2)" "unprognostic (4.45e-2)" "unprognostic (9.14e-2)" "unprognostic (2.32e-2)" "unprognostic (5.73e-2)" "unprognostic (5.18e-2)" "unprognostic (5.92e-2)" "unprognostic (3.02e-1)" "unprognostic (2.48e-2)" "unprognostic (1.32e-1)" "unprognostic (9.72e-2)" 40.5 28.4 5.5 158.9 5.3 160.9 15.2 6.5 5.5 12.3 12.4 22.3 19.3 9.3 4.3 8.9 9.9 26.2 8.0 4.7 9.1 8.0 27.5 91.5 97.1 15.1 9.6 6.9 4.0 4.4 2.5 54.6 13.3 6.7 30.6 1.7 7.0 9.7 3.7 2.2 22.3 55.5 12.5 89.0 17.2 4.7 11.1 18.3 5.3 5.5 73.2 46.8 2.3 24.0 1.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 52.8 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.4 3.6 0.6 0.0 0.0 3.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.5 0.0 0.0 0.1 64.2 0.2 0.0 0.3 54.6 0.0 210.4 0.0 0.1 0.4 0.1 0.0 0.4 0.0 0.0 0.1 20.0 0.0 0.0 0.1 0.1 0.2 0.6 1.6 3.4 0.0 8.9 0.0 2.2 276.3 110.5 0.4 261.6 0.5 39.6 0.3 0.4 62.8 32.8 0.3 0.2 19.2 0.6 237.1 90.9 0.9 162.5 5.5 5.3 6.5 5.5 4.7 9.1 15.1 9.6 13.3 12.5 11.1 24.0 2.4 25.6 25.4 0.7 99.9 1.0 0.1 0.0 0.6 0.1 1.0 3.0 11.0 2.8 13.0 1.8 0.0 0.9 82.7 2.0 0.0 0.0 0.6 0.2 0.1 8.1 0.0 5.2 1.6 0.4 1.1 4.4 4.1 0.1 7.6 0.1 5.0 3.2 157.2 1.7 1.6 0.7 0.0 456.0 25.0 0.7 0.6 469.3 1.8 76.8 396.6 0.1 14.4 0.0 0.1 0.1 0.5 0.0 13.6 0.0 0.6 0.5 7.3 0.7 13.1 1.6 1.2 0.0 0.6 1.9 1.3 1.8 7.5 0.0 1.3 0.1 DHRS7 "retDSR4, SDR34C1" ENSG00000100612 "Dehydrogenase/reductase 7" Q9Y394 14 60144119-60169856 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 615.8" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 840.4" "Cancer enriched" "Detected in all" 5 "prostate cancer: 199.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031121, HPA078401" Enhanced Approved Nucleoplasm,Mitochondria No No "Cluster 5: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Mitochondria" "HPA031121: AB_10600803, HPA078401: " "prognostic favorable (6.42e-4)" "unprognostic (5.20e-2)" "unprognostic (6.70e-3)" "unprognostic (1.67e-1)" "unprognostic (2.69e-1)" "prognostic unfavorable (2.51e-4)" "unprognostic (4.65e-2)" "unprognostic (4.31e-2)" "unprognostic (2.62e-1)" "prognostic unfavorable (7.99e-4)" "unprognostic (1.73e-1)" "unprognostic (1.59e-1)" "prognostic favorable (1.92e-10)" "unprognostic (8.35e-3)" "unprognostic (1.48e-1)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" 62.1 103.4 50.8 43.8 53.9 61.0 58.5 59.2 75.4 48.9 50.2 73.0 108.9 49.8 96.5 44.3 45.9 59.1 47.1 49.9 55.1 100.5 146.4 64.2 45.5 62.3 54.9 64.9 76.8 226.8 54.7 29.6 63.3 409.9 69.5 111.1 317.5 134.6 615.8 46.6 181.0 51.0 57.8 45.4 182.3 9.8 52.0 39.2 120.3 136.0 49.4 51.7 41.1 65.6 221.3 52.9 41.8 89.3 219.6 74.4 42.8 74.3 186.4 26.5 59.0 37.3 149.8 21.5 41.7 76.8 78.0 92.7 57.2 108.3 34.5 156.1 36.0 53.7 28.7 60.9 110.1 71.8 1.7 63.3 116.7 47.6 153.0 50.8 52.5 66.2 18.2 52.6 61.4 59.2 40.9 67.2 18.6 151.2 55.4 42.7 50.8 24.4 118.3 70.5 83.4 99.8 72.6 118.0 168.2 52.7 72.7 32.5 35.8 126.6 38.7 36.9 44.2 18.3 7.9 45.0 62.6 64.8 93.5 743.5 213.1 519.6 335.7 159.1 340.6 184.4 238.9 298.5 185.0 167.0 134.6 258.5 835.4 294.7 224.0 388.8 215.5 450.2 50.8 53.9 59.2 75.4 49.9 55.1 62.3 54.9 63.3 57.8 52.0 65.6 109.6 54.5 102.5 16.0 72.2 34.0 70.3 233.2 52.3 25.7 81.2 57.4 27.6 160.2 138.4 86.5 83.4 29.6 210.4 101.3 19.6 222.5 2.1 56.2 55.5 89.7 46.5 20.4 12.2 165.9 88.7 87.9 120.8 120.0 178.5 22.9 48.5 166.4 94.4 42.1 19.0 102.2 386.6 54.5 70.6 3.5 82.3 98.7 108.5 16.9 172.5 94.4 299.7 26.2 20.1 210.6 114.5 84.2 99.0 263.4 840.4 44.1 57.0 70.7 85.5 66.4 73.7 1.6 2.9 47.0 25.4 20.8 152.1 19.7 79.2 47.1 DOK2 "Dok-2, p56dok-2" ENSG00000147443 "Docking protein 2" O60496 8 21908873-21913690 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 25.6;lymphoid tissue: 40.9" "Cell type enhanced" "Detected in many" "dendritic cells: 130.6;Hofbauer cells: 131.8;Kupffer cells: 171.8;Langerhans cells: 288.4;Macrophages: 181.5;NK-cells: 344.0;T-cells: 147.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1565.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 25.3;HEL: 54.3;HMC-1: 119.8;JURKAT: 22.3;THP-1: 43.1;U-937: 42.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB004379, HPA005507, HPA066571" Enhanced Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus,Cytosol" NA NA 220000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Nucleoplasm, Nuclear bodies, Golgi apparatus" "CAB004379: AB_627449, HPA005507: , HPA066571: AB_2732749" "unprognostic (5.39e-2)" "unprognostic (8.84e-3)" "unprognostic (8.72e-3)" "unprognostic (1.74e-3)" "unprognostic (2.14e-2)" "unprognostic (2.30e-3)" "unprognostic (1.34e-1)" "unprognostic (7.22e-2)" "prognostic favorable (4.31e-4)" "unprognostic (2.22e-1)" "unprognostic (4.19e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (1.88e-1)" "unprognostic (1.24e-2)" "unprognostic (3.19e-1)" "unprognostic (2.80e-1)" 9.5 5.0 1.1 26.5 1.2 19.5 5.0 1.2 2.3 1.9 2.5 5.5 7.0 2.2 0.5 2.3 3.5 6.5 3.5 1.3 1.3 3.0 6.1 25.6 26.3 1.4 1.5 1.4 1.9 0.5 1.1 7.9 1.5 2.3 3.6 0.0 3.4 1.5 2.0 2.3 9.5 6.9 1.2 40.9 6.8 1.6 4.5 16.4 2.4 1.6 7.8 8.4 2.3 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.3 0.0 54.3 0.0 0.1 0.0 0.4 119.8 0.0 0.0 0.0 0.0 0.0 0.0 22.3 0.8 5.0 0.0 0.0 0.9 8.7 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.3 0.0 0.1 0.2 0.1 0.2 0.1 0.3 1.4 42.0 0.2 577.6 484.3 1565.6 398.3 624.0 184.5 14.5 274.3 304.8 421.9 6.6 151.0 185.9 37.2 307.6 580.7 7.6 597.2 810.3 1.1 1.2 1.2 2.3 1.3 1.3 1.4 1.5 1.5 1.2 4.5 1.5 2.0 3.2 18.1 0.0 13.2 11.5 0.6 0.0 0.0 0.0 1.2 1.8 2.1 0.0 1.3 3.7 0.0 0.7 130.6 0.3 0.0 0.1 0.2 0.2 0.5 2.8 0.0 10.5 0.1 0.0 1.0 2.6 3.1 0.4 36.3 0.1 5.7 1.1 131.8 0.0 0.0 0.2 0.0 171.8 288.4 0.6 0.3 181.5 19.6 0.0 74.8 0.0 344.0 0.0 0.0 0.0 0.0 0.0 15.4 0.2 0.0 0.7 1.5 0.0 0.0 0.6 2.5 0.2 4.3 0.7 8.5 1.0 147.4 0.0 0.2 0.8 EBI3 "IL27B, IL35B" ENSG00000105246 "Epstein-Barr virus induced 3" Q14213 19 4229523-4237528 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "placenta: 147.6" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 485.6;monocytes: 505.7;Syncytiotrophoblasts: 336.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "intermediate monocyte: 4.8;memory B-cell: 18.7;naive B-cell: 14.7;non-classical monocyte: 6.3" "Group enriched" "Detected in many" 14 "B-cells: 18.7;monocytes: 6.3" "Cell line enriched" "Detected in some" 13 "HDLM-2: 218.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA046635 Enhanced "Secreted to blood" NA NA 203000 1400000 "Cluster 19: B-cells - Humoral immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 44: HDLM-2 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA046635: AB_2679729" "unprognostic (7.26e-2)" "unprognostic (1.49e-2)" "unprognostic (9.44e-2)" "unprognostic (1.31e-1)" "unprognostic (2.59e-1)" "unprognostic (2.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.10e-2)" "unprognostic (7.78e-2)" "unprognostic (4.87e-2)" "unprognostic (4.25e-3)" "unprognostic (8.27e-2)" "prognostic unfavorable (1.04e-8)" "unprognostic (1.97e-1)" "unprognostic (2.78e-2)" "unprognostic (9.29e-2)" "unprognostic (4.67e-2)" 4.7 4.7 3.8 14.6 3.3 1.2 1.7 3.4 5.3 1.5 3.2 3.0 4.3 1.1 0.1 1.0 2.4 5.4 1.4 3.8 3.7 2.1 3.3 2.9 20.2 5.7 4.2 1.3 2.5 0.4 1.7 147.6 5.2 1.8 1.6 0.1 1.8 1.4 0.2 0.6 8.4 2.1 4.5 34.0 3.7 0.9 5.8 9.4 0.9 0.4 7.3 4.8 1.0 6.1 0.1 1.7 0.1 0.0 0.0 0.0 7.3 0.7 4.2 0.4 0.2 1.3 1.2 4.2 16.4 0.0 2.0 0.1 0.0 0.0 0.0 218.8 0.0 0.0 0.1 0.2 0.3 0.0 7.7 0.4 0.0 2.1 0.6 1.6 0.1 0.0 0.4 0.5 0.1 0.1 0.0 3.0 0.4 0.0 0.0 0.0 0.6 0.3 2.6 0.0 0.2 0.4 0.0 0.0 0.0 2.7 0.2 0.2 0.9 0.3 5.1 0.0 0.2 0.4 0.0 0.2 0.3 0.0 0.6 0.0 0.1 0.0 0.0 4.8 0.0 18.7 0.0 0.0 0.8 14.7 0.0 0.0 0.2 0.0 6.3 0.0 0.0 0.6 3.8 3.3 3.4 5.3 3.8 3.7 5.7 4.2 5.2 4.5 5.8 6.1 0.5 0.0 0.5 0.3 8.4 0.4 0.0 13.3 0.0 0.0 0.2 0.6 0.1 1.5 10.7 0.0 0.0 10.6 0.5 0.0 0.0 2.8 0.0 0.3 0.4 1.3 0.0 0.0 0.6 0.9 485.6 0.7 0.0 0.3 11.4 0.0 1.1 0.1 9.6 0.0 0.4 0.0 6.1 102.6 11.3 0.0 0.0 19.0 0.0 5.6 505.7 0.1 0.0 0.0 0.1 0.6 0.0 0.0 2.6 0.1 0.0 0.6 1.5 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.1 336.4 1.0 0.1 0.0 0.1 FCER1G ENSG00000158869 "Fc fragment of IgE receptor Ig" P30273 1 161215234-161220699 "FDA approved drug targets, Predicted membrane proteins" "Immunity, Innate immunity" "IgE-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 441.6;lymphoid tissue: 470.1" "Group enriched" "Detected in many" 9 "dendritic cells: 726.6;granulocytes: 705.6;Hofbauer cells: 2318.6;Kupffer cells: 1950.8;Langerhans cells: 1526.3;Macrophages: 1971.3;monocytes: 808.9;NK-cells: 1037.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 11 "basophil: 1987.3;classical monocyte: 3240.2;intermediate monocyte: 5333.6;myeloid DC: 2386.3;neutrophil: 1831.0;NK-cell: 1750.9;non-classical monocyte: 6984.5;plasmacytoid DC: 3315.6" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "HEL: 77.8;HMC-1: 301.7;THP-1: 276.1;U-266/84: 90.1;U-937: 87.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022108, HPA026872" Supported NA NA 270000 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB022108: , HPA026872: AB_1848473" "unprognostic (3.71e-2)" "unprognostic (2.52e-2)" "unprognostic (2.40e-2)" "unprognostic (8.73e-3)" "unprognostic (1.46e-1)" "unprognostic (4.28e-2)" "unprognostic (3.10e-3)" "unprognostic (1.84e-1)" "unprognostic (3.25e-1)" "unprognostic (9.63e-2)" "unprognostic (2.28e-2)" "unprognostic (5.67e-2)" "prognostic unfavorable (1.83e-6)" "unprognostic (1.99e-1)" "unprognostic (6.28e-2)" "unprognostic (2.04e-2)" "unprognostic (7.87e-2)" 251.7 86.5 34.0 275.6 33.8 441.6 62.9 35.5 66.0 52.5 47.5 82.7 44.9 30.7 38.7 30.6 72.0 101.5 53.1 33.7 42.0 40.3 177.3 286.6 160.9 53.4 48.7 19.9 22.3 26.8 26.9 211.0 50.1 31.0 113.2 8.3 42.9 38.8 11.9 21.0 60.6 160.3 41.5 470.1 39.4 14.5 49.9 62.7 25.5 34.6 82.5 254.6 21.7 65.4 0.2 0.0 0.7 1.3 1.8 0.7 0.4 0.5 0.2 0.5 0.8 2.2 0.1 0.5 0.7 0.0 0.3 0.2 0.5 0.0 0.4 0.3 1.5 77.8 0.6 14.0 0.3 16.1 301.7 6.0 3.3 2.3 0.2 0.7 0.4 1.8 0.1 7.3 2.4 0.5 1.4 37.9 1.6 0.0 0.0 0.1 6.7 0.2 0.5 0.4 0.3 1.0 0.6 0.1 2.7 1.4 0.2 276.1 0.4 1.8 0.4 0.9 1.1 3.0 90.1 0.9 1.7 87.1 0.5 1987.3 3240.2 307.3 13.6 5333.6 15.9 28.2 10.6 10.6 2386.3 9.0 17.3 45.0 1831.0 1750.9 6984.5 3315.6 21.8 4265.5 34.0 33.8 35.5 66.0 33.7 42.0 53.4 48.7 50.1 41.5 49.9 65.4 12.8 86.6 147.7 0.7 35.9 39.6 1.5 0.2 1.8 0.1 5.2 22.1 6.8 15.7 27.3 18.4 0.0 14.5 726.6 1.0 0.0 1.9 3.0 1.0 0.9 38.6 1.8 79.3 0.1 1.0 18.8 18.3 1.1 1.0 705.6 0.5 41.0 13.6 2318.6 0.0 0.2 0.5 0.0 1950.8 1526.3 9.4 5.3 1971.3 80.0 12.2 808.9 0.2 1037.1 0.0 0.1 1.0 1.4 1.2 10.1 1.3 0.4 5.4 15.3 2.3 72.3 3.8 11.2 1.0 2.5 1.4 35.9 23.7 133.3 0.4 0.6 1.8 FCGBP FC(GAMMA)BP ENSG00000275395 "Fc fragment of IgG binding protein" 19 39863323-39934626 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 206.9;salivary gland: 85.4;stomach 1: 85.5;thyroid gland: 99.9" "Cell type enriched" "Detected in many" 9 "Intestinal goblet cells: 6081.9" "Cancer enhanced" "Detected in all" "colorectal cancer: 63.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.6;Daudi: 1.8;JURKAT: 1.7;MOLT-4: 1.8;RH-30: 7.1" "HPA003517, HPA003564" Enhanced Approved "Golgi apparatus,Plasma membrane,Cytokinetic bridge" "Secreted in other tissues" Yes NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "Golgi apparatus, Cytokinetic bridge" "HPA003517: AB_1078838, HPA003564: AB_2231648" "unprognostic (1.65e-2)" "unprognostic (1.92e-2)" "unprognostic (1.62e-3)" "unprognostic (1.77e-2)" "unprognostic (2.04e-2)" "prognostic favorable (1.28e-5)" "prognostic unfavorable (4.74e-5)" "unprognostic (1.36e-2)" "unprognostic (1.83e-1)" "prognostic unfavorable (9.70e-6)" "unprognostic (9.44e-2)" "unprognostic (3.03e-2)" "unprognostic (5.92e-3)" "unprognostic (8.60e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (4.27e-4)" "unprognostic (2.08e-1)" 5.9 10.0 5.1 14.0 7.2 0.4 3.2 4.0 8.4 56.4 15.0 206.9 68.7 1.2 0.6 4.6 9.8 49.2 2.9 5.6 6.8 11.3 1.0 1.9 0.9 20.1 10.6 3.7 4.9 0.5 3.4 2.9 11.1 3.8 67.7 0.6 85.4 1.4 0.4 14.8 148.7 2.6 5.9 1.5 85.5 2.9 14.0 1.5 99.9 0.0 0.7 3.4 1.6 12.0 0.0 4.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.2 0.0 0.1 1.8 0.6 0.1 1.5 0.3 0.1 7.1 1.6 0.1 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.2 0.4 0.1 0.1 0.5 0.0 0.3 0.1 0.0 0.0 0.1 5.1 7.2 4.0 8.4 5.6 6.8 20.1 10.6 11.1 5.9 14.0 12.0 0.6 3.2 5.1 2.6 4.6 3.7 1.9 15.8 1.2 1.1 1.3 3.4 2.8 70.1 60.0 25.8 0.0 0.7 1.8 622.2 0.0 5.2 7.2 4.2 0.3 26.7 81.1 0.0 0.6 0.9 0.4 1.9 552.0 4.0 15.9 0.4 0.7 1.3 44.0 0.0 0.4 6081.9 2.0 30.2 12.6 9.2 0.9 21.6 8.8 15.9 0.9 0.4 1.0 0.5 0.2 3.9 253.6 0.0 2.1 13.8 413.5 1.2 11.0 2.0 59.2 0.5 1.1 0.5 2.4 0.4 6.8 0.4 5.6 0.9 191.4 164.1 FCGR2A "CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, IGFR2" ENSG00000143226 "Fc fragment of IgG receptor IIa" P12318 1 161505430-161524013 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 101.7;placenta: 107.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 178.2;Kupffer cells: 159.1;Langerhans cells: 336.6;Macrophages: 305.0;monocytes: 97.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 2322.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 2322.4" "Cell line enhanced" "Detected in some" "HEL: 29.4;HMC-1: 56.2;K-562: 17.9;NB-4: 15.8;THP-1: 61.9;U-937: 26.7" "HPA010718, HPA010776, HPA014730" Enhanced Supported "Golgi apparatus,Plasma membrane" NA NA 46000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Golgi apparatus" "HPA010718: AB_1078463, HPA010776: , HPA014730: AB_2669074" "unprognostic (2.57e-2)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (4.12e-2)" "unprognostic (5.89e-2)" "unprognostic (6.17e-2)" "unprognostic (1.24e-2)" "unprognostic (1.17e-1)" "unprognostic (7.63e-2)" "unprognostic (1.17e-3)" "unprognostic (2.43e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (6.49e-7)" "unprognostic (8.85e-3)" "unprognostic (6.47e-3)" "unprognostic (1.54e-1)" "unprognostic (3.42e-2)" 68.0 24.8 7.3 101.7 6.6 48.6 13.3 8.0 12.1 18.1 13.9 16.0 8.1 7.3 4.3 11.7 14.6 36.8 11.5 6.5 11.5 12.7 12.3 77.5 16.1 15.1 11.4 7.2 12.7 8.5 7.6 107.3 13.3 6.1 21.0 2.3 9.9 9.6 2.6 3.5 10.8 40.9 11.9 61.8 10.1 4.4 13.8 9.8 6.4 10.2 7.7 68.3 5.2 21.8 0.0 0.0 0.0 2.4 0.0 0.3 0.0 0.0 0.5 0.0 0.1 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 29.4 0.3 0.0 0.7 8.6 56.2 0.5 0.0 0.0 0.0 0.7 0.1 0.0 17.9 0.5 0.0 0.0 0.4 15.8 0.0 0.0 1.1 0.2 1.2 8.1 0.0 0.0 0.1 0.0 0.0 0.0 4.6 0.0 0.0 61.9 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.7 0.4 26.7 6.6 2.4 358.3 421.8 0.7 268.4 1.0 3.2 0.5 0.4 89.9 1.7 0.4 0.7 2322.4 0.4 232.7 3.8 0.9 170.3 7.3 6.6 8.0 12.1 6.5 11.5 15.1 11.4 13.3 11.9 13.8 21.8 2.3 22.4 49.1 0.0 8.6 8.7 0.9 0.3 1.2 0.4 1.1 3.8 1.8 2.8 12.1 0.0 0.0 1.0 3.4 0.1 9.8 0.2 38.2 0.1 0.8 15.6 0.0 3.0 0.1 0.6 1.6 8.9 1.1 0.1 30.4 0.1 3.9 2.1 178.2 0.0 0.1 0.0 0.0 159.1 336.6 66.5 1.5 305.0 17.8 12.2 97.3 0.5 7.2 1.0 0.6 0.5 0.0 0.0 4.6 0.3 0.0 9.6 3.7 0.2 6.6 1.5 6.0 0.4 0.6 0.8 7.7 1.6 4.8 0.2 0.1 0.4 FCGR3A "CD16, CD16a, FCG3, FCGR3" ENSG00000203747 "Fc fragment of IgG receptor IIIa" P08637 1 161541759-161550737 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 206.3;lymphoid tissue: 306.8" "Cell type enhanced" "Detected in many" "dendritic cells: 333.4;Hofbauer cells: 193.1;Kupffer cells: 807.9;Macrophages: 300.0;NK-cells: 579.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "intermediate monocyte: 1763.5;neutrophil: 1169.8;non-classical monocyte: 3948.7" "Group enriched" "Detected in all" 5 "granulocytes: 1169.8;monocytes: 3948.7" "Not detected" "Not detected" "CAB032435, HPA055431" Supported "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB032435: AB_626925, HPA055431: AB_2682815" "unprognostic (5.27e-2)" "unprognostic (9.95e-2)" "unprognostic (2.37e-2)" "unprognostic (1.66e-1)" "unprognostic (1.39e-1)" "unprognostic (1.82e-1)" "unprognostic (2.24e-2)" "unprognostic (6.06e-2)" "unprognostic (2.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.98e-2)" "unprognostic (7.52e-2)" "prognostic unfavorable (3.22e-6)" "unprognostic (1.14e-1)" "unprognostic (4.66e-2)" "unprognostic (1.03e-2)" "unprognostic (7.51e-2)" 52.9 41.9 18.4 99.8 20.4 27.3 14.7 19.3 27.2 8.2 26.5 12.5 5.8 5.9 5.9 4.9 9.1 24.5 22.3 16.9 22.0 7.9 111.5 206.3 37.1 37.7 27.9 6.6 7.8 13.6 11.3 71.0 30.6 6.9 12.6 6.9 14.7 7.6 3.3 2.2 5.7 68.4 31.7 306.8 6.8 7.7 28.8 9.3 7.0 4.3 3.9 32.5 3.5 39.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.5 26.2 9.6 513.6 1763.5 4.9 3.7 4.7 205.9 175.8 1.4 3.0 184.0 1169.8 136.2 3948.7 4.6 2.6 734.1 18.4 20.4 19.3 27.2 16.9 22.0 37.7 27.9 30.6 31.7 28.8 39.8 2.7 22.4 24.6 0.7 6.5 0.5 0.1 0.0 0.0 0.2 1.4 3.4 0.7 8.6 10.5 3.7 2.1 1.2 333.4 0.0 0.0 0.2 1.4 0.1 0.0 18.9 0.0 16.4 0.0 0.0 1.4 3.9 0.0 0.1 18.9 0.1 8.6 5.3 193.1 0.0 0.1 0.1 0.0 807.9 7.4 3.7 0.3 300.0 0.0 20.6 77.2 0.1 579.9 0.0 0.1 0.0 0.0 0.0 22.1 0.0 0.0 0.8 5.8 1.5 19.7 1.1 0.4 0.0 0.5 0.2 0.0 2.1 88.0 0.0 0.0 0.3 FGD2 ZFYVE4 ENSG00000146192 "FYVE, RhoGEF and PH domain containing 2" Q7Z6J4 6 37005646-37029069 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.7" "Cell type enhanced" "Detected in many" "B-cells: 53.7;dendritic cells: 29.7;Kupffer cells: 118.2;Langerhans cells: 49.3;Macrophages: 52.0;Microglial cells: 43.1;monocytes: 51.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 22.3;intermediate monocyte: 64.8;memory B-cell: 23.2;myeloid DC: 35.0;naive B-cell: 18.6;non-classical monocyte: 70.5;plasmacytoid DC: 27.4" "Group enriched" "Detected in many" 18 "B-cells: 23.2;dendritic cells: 35.0;monocytes: 70.5" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.7;Daudi: 11.5;HDLM-2: 11.3;U-698: 9.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029145, HPA049692" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA029145: AB_10601321, HPA049692: AB_2680852" "unprognostic (3.54e-2)" "unprognostic (1.40e-4)" "unprognostic (5.69e-3)" "unprognostic (2.29e-1)" "unprognostic (1.27e-1)" "unprognostic (1.67e-4)" "unprognostic (7.97e-2)" "unprognostic (1.58e-2)" "unprognostic (2.47e-2)" "unprognostic (2.78e-1)" "unprognostic (3.39e-2)" "unprognostic (2.82e-1)" "unprognostic (1.15e-2)" "unprognostic (3.91e-1)" "unprognostic (1.02e-2)" "unprognostic (3.88e-1)" "unprognostic (7.10e-2)" 6.1 3.3 1.0 14.8 1.3 6.0 2.6 1.2 1.3 1.5 2.3 3.4 3.7 1.3 1.5 2.4 2.8 4.1 1.6 1.0 1.6 1.4 2.5 8.0 22.5 3.2 1.7 1.0 1.3 0.3 1.1 2.7 1.9 1.5 2.7 0.1 2.3 1.8 0.6 2.1 11.1 4.7 2.1 39.7 3.8 0.6 2.1 5.5 2.7 0.9 9.8 4.5 1.6 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 11.5 0.0 0.0 0.0 0.4 0.0 0.0 0.3 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 1.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.1 22.3 2.3 0.1 64.8 0.1 23.2 0.0 0.0 35.0 18.6 0.0 0.0 0.3 0.4 70.5 27.4 0.1 7.5 1.0 1.3 1.2 1.3 1.0 1.6 3.2 1.7 1.9 2.1 2.1 2.0 0.3 6.4 7.4 0.0 53.7 2.0 3.0 1.0 0.6 0.3 0.7 0.6 3.2 2.8 0.5 0.0 0.0 0.3 29.7 0.3 0.0 2.8 11.9 0.5 0.2 1.2 0.0 1.3 0.1 0.9 0.4 1.0 1.5 1.2 7.6 0.0 2.5 0.6 17.7 0.0 0.2 0.1 4.1 118.2 49.3 2.1 1.5 52.0 1.8 43.1 51.8 0.4 2.1 0.5 0.2 1.0 3.9 0.0 14.2 1.6 0.1 0.2 3.2 0.2 0.0 2.3 0.5 0.0 0.1 3.3 2.3 0.4 3.0 0.1 0.4 5.6 FOLR2 FRβ ENSG00000165457 "Folate receptor beta" P14207 11 72216601-72221950 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Transport Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 168.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 1114.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 64.2;intermediate monocyte: 50.6" "Group enriched" "Detected in many" 4 "dendritic cells: 18.7;monocytes: 64.2" "Cell line enriched" "Detected in some" 5 "U-698: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 15000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (2.03e-1)" "unprognostic (6.58e-3)" "prognostic unfavorable (8.42e-4)" "unprognostic (1.47e-1)" "unprognostic (2.76e-1)" "unprognostic (2.83e-1)" "unprognostic (1.39e-1)" "unprognostic (3.36e-1)" "unprognostic (3.38e-1)" "unprognostic (2.51e-1)" "unprognostic (8.11e-2)" "unprognostic (1.16e-1)" "unprognostic (3.91e-3)" "unprognostic (6.16e-3)" "unprognostic (1.14e-1)" "prognostic favorable (8.41e-4)" "unprognostic (7.98e-3)" 119.1 55.0 10.7 28.2 11.0 10.8 31.7 8.2 18.6 27.9 13.8 36.0 19.5 13.5 12.4 31.6 16.8 80.1 38.6 10.9 9.5 10.8 44.8 39.7 78.5 9.3 10.7 16.0 7.1 7.9 6.1 168.4 11.4 6.1 46.7 0.2 12.8 16.7 5.9 9.8 29.6 46.3 9.3 27.7 21.0 13.0 16.2 28.7 9.1 26.3 29.0 81.3 6.3 16.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.7 0.2 0.2 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.2 0.0 0.2 0.0 18.6 0.5 0.8 0.0 0.0 64.2 0.0 0.3 50.6 0.0 9.5 0.0 0.0 18.7 4.0 0.0 0.0 1.1 1.8 13.7 0.2 0.0 20.4 10.7 11.0 8.2 18.6 10.9 9.5 9.3 10.7 11.4 9.3 16.2 16.1 3.4 0.0 0.6 0.0 8.0 7.9 0.1 0.0 1.2 0.0 0.1 1.1 2.2 1.5 0.0 0.0 0.0 7.6 0.6 0.0 0.0 0.0 0.9 0.3 0.1 2.3 0.0 0.0 0.0 0.0 6.0 2.4 0.0 0.5 2.5 0.0 2.2 1.7 1114.8 0.0 0.0 0.0 0.0 229.3 98.8 2.5 1.5 199.4 0.0 15.9 5.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 2.1 0.1 0.0 0.2 0.0 0.3 0.0 2.5 1.2 0.6 0.7 1.3 5.1 16.0 1.2 0.1 0.0 0.1 FPR3 "FMLPY, FPRH1, FPRL2, RMLP-R-I" ENSG00000187474 "Formyl peptide receptor 3" P25089 19 51795157-51826190 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 28.2" "Group enriched" "Detected in some" 15 "Hofbauer cells: 56.5;Kupffer cells: 97.4;Langerhans cells: 223.6;Macrophages: 66.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 20 "classical monocyte: 2.3;intermediate monocyte: 6.7;myeloid DC: 2.4" "Group enriched" "Detected in many" 44 "dendritic cells: 2.4;monocytes: 6.7" "Group enriched" "Detected in some" 5 "HEL: 10.0;hTERT-RPE1: 2.7" "Not detected" "Not detected" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.77e-2)" "unprognostic (1.54e-1)" "unprognostic (1.79e-2)" "unprognostic (1.29e-1)" "unprognostic (1.15e-1)" "unprognostic (1.84e-1)" "unprognostic (8.41e-2)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" "unprognostic (7.14e-2)" "unprognostic (3.17e-1)" "unprognostic (9.37e-2)" "unprognostic (1.02e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (9.13e-4)" "unprognostic (1.96e-1)" "unprognostic (4.28e-2)" 10.6 12.1 0.6 23.9 1.1 0.4 5.3 0.5 2.4 5.5 2.2 12.6 11.2 3.7 1.5 5.7 2.0 18.8 3.8 0.6 0.7 3.2 21.3 28.2 13.9 3.1 1.0 1.7 2.3 2.2 0.9 5.6 2.8 2.5 18.2 0.3 2.4 2.9 0.9 2.7 14.4 8.9 1.2 16.3 7.1 2.7 6.0 8.1 2.2 2.0 11.0 17.4 1.2 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.3 0.0 0.0 6.7 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.6 1.1 0.5 2.4 0.6 0.7 3.1 1.0 2.8 1.2 6.0 3.9 0.5 0.0 1.7 0.3 2.7 5.6 0.0 0.0 0.0 0.1 0.1 0.5 0.2 0.0 2.5 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.4 0.8 0.0 0.0 0.0 0.0 1.1 1.5 56.5 0.0 0.2 0.0 0.0 97.4 223.6 0.2 0.3 66.6 7.2 1.0 3.7 0.0 0.0 0.0 0.7 0.0 0.0 1.2 0.4 0.1 0.0 0.0 1.5 0.1 0.0 0.3 0.5 0.0 0.1 0.4 4.5 0.8 0.6 0.0 0.0 0.1 FUCA1 ENSG00000179163 "Alpha-L-fucosidase 1" P04066 1 23845077-23868290 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 181.7;Distal enterocytes: 226.6;Paneth cells: 221.0;Proximal enterocytes: 210.9;Syncytiotrophoblasts: 200.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 165.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046542, HPA056371" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 60000000 "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA046542: AB_2679691, HPA056371: AB_2683108" "unprognostic (6.94e-3)" "unprognostic (6.53e-2)" "unprognostic (2.68e-3)" "prognostic favorable (2.45e-4)" "unprognostic (5.64e-3)" "unprognostic (2.59e-3)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (4.99e-1)" "unprognostic (2.18e-2)" "unprognostic (2.05e-1)" "unprognostic (4.23e-2)" "prognostic favorable (5.70e-13)" "unprognostic (3.75e-2)" "unprognostic (4.35e-2)" "unprognostic (1.54e-2)" "unprognostic (2.13e-3)" 34.2 34.4 8.3 49.8 8.2 7.7 26.3 8.3 11.2 54.5 23.8 124.2 90.3 20.7 113.0 17.0 51.1 46.6 20.6 8.3 10.5 78.2 104.8 55.1 168.2 9.5 8.8 23.8 23.9 56.9 17.6 72.6 9.6 50.2 140.7 5.7 40.8 60.4 15.8 14.9 81.3 26.7 9.3 71.8 63.9 27.7 10.8 26.8 70.6 17.7 94.1 74.9 13.2 12.8 15.9 10.6 2.2 31.9 4.2 0.3 11.0 16.6 34.4 17.1 31.6 14.5 165.1 23.9 40.9 21.3 18.8 9.4 15.3 35.4 22.4 16.9 25.6 19.7 9.2 32.7 14.2 2.0 62.7 15.3 19.7 6.2 8.1 55.2 6.9 13.3 9.3 0.5 20.6 17.5 5.0 17.7 5.4 48.1 16.9 26.9 0.2 26.2 63.5 40.5 10.9 10.6 47.9 18.5 26.2 17.9 13.6 7.8 1.8 5.8 9.0 38.9 5.6 28.5 31.0 8.5 14.5 58.9 9.5 54.8 100.4 51.9 27.2 99.9 23.1 23.8 19.5 22.9 44.0 14.1 18.9 22.0 12.8 44.6 91.1 25.4 21.4 64.8 8.3 8.2 8.3 11.2 8.3 10.5 9.5 8.8 9.6 9.3 10.8 12.8 12.9 25.6 28.6 4.2 10.5 3.6 27.4 99.3 6.8 4.4 22.2 10.4 5.6 40.0 77.8 84.6 0.0 181.7 13.9 226.6 15.6 64.1 61.0 31.5 2.8 11.6 10.8 20.6 5.8 50.3 24.2 16.7 33.1 13.3 8.2 11.1 25.7 42.7 156.4 0.0 6.3 44.4 44.7 121.0 13.5 24.4 23.3 85.4 8.8 2.8 29.6 13.0 10.3 4.0 4.7 34.9 221.0 19.5 8.7 23.6 210.9 40.2 53.7 5.0 6.6 16.7 13.2 109.0 24.8 8.5 2.8 200.6 11.2 34.6 79.5 40.3 GBA "GBA1, GLUC" ENSG00000177628 "Glucosylceramidase beta" P04062 1 155234452-155244699 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Sphingolipid metabolism, Steroid metabolism, Sterol metabolism" "Glycosidase, Glycosyltransferase, Hydrolase, Transferase" "Disease variant, Gaucher disease, Ichthyosis, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 65.2;Syncytiotrophoblasts: 59.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006667, CAB037171, CAB037289" Supported "Intracellular and membrane" NA NA 470000 "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" "CAB037171: AB_1078958, CAB037289: AB_1078957, HPA006667: AB_1078979" "unprognostic (6.03e-2)" "unprognostic (6.02e-2)" "unprognostic (3.41e-1)" "unprognostic (2.42e-1)" "unprognostic (6.00e-3)" "unprognostic (2.97e-1)" "unprognostic (1.04e-3)" "unprognostic (4.76e-2)" "unprognostic (1.22e-1)" "unprognostic (6.02e-2)" "unprognostic (1.73e-1)" "unprognostic (1.33e-1)" "unprognostic (1.47e-1)" "unprognostic (1.76e-1)" "unprognostic (3.04e-2)" "unprognostic (3.15e-1)" "unprognostic (2.94e-2)" 23.9 37.9 22.5 24.8 24.4 41.7 25.1 25.9 24.3 26.7 27.4 35.1 23.9 22.9 50.2 27.6 20.5 28.3 19.1 26.1 27.7 33.6 33.7 28.3 19.9 27.3 28.0 16.9 33.4 103.1 43.8 39.2 36.2 23.3 39.8 12.4 26.8 33.6 9.1 33.4 22.5 29.7 25.0 29.0 22.7 8.8 29.2 19.7 37.7 13.6 28.0 27.1 21.9 29.5 38.0 72.2 25.1 34.2 254.8 55.8 29.3 65.4 230.4 95.3 119.0 43.2 135.7 26.3 70.4 153.7 152.0 76.2 35.9 46.4 50.3 55.5 25.1 21.8 45.1 23.2 73.6 25.8 87.0 73.4 38.2 199.7 30.2 100.2 85.6 22.2 23.4 42.9 113.5 82.6 32.5 11.9 16.3 61.9 51.2 26.8 41.9 108.1 63.9 29.0 23.9 33.5 57.4 136.4 145.3 45.6 102.6 63.3 65.7 71.7 31.7 91.9 53.7 86.2 78.6 20.4 126.6 23.4 56.4 21.4 36.0 15.3 20.8 35.8 13.2 11.1 15.7 13.8 22.4 7.8 11.0 11.7 28.9 11.6 37.2 12.5 23.4 23.3 22.5 24.4 25.9 24.3 26.1 27.7 27.3 28.0 36.2 25.0 29.2 29.5 6.8 3.2 5.1 3.3 8.8 6.0 5.8 9.5 4.6 4.0 12.7 6.5 8.8 17.2 8.1 12.9 2.1 30.7 6.2 36.1 3.9 30.5 1.4 12.3 9.7 12.2 14.6 7.4 3.4 32.4 27.9 18.6 20.9 17.9 7.0 7.9 17.2 23.2 65.2 5.0 2.7 11.6 4.1 33.3 9.9 2.8 9.9 26.8 26.6 1.0 22.8 11.7 12.3 0.5 3.3 29.5 15.8 9.1 19.8 6.7 28.6 20.6 8.5 6.0 0.0 9.4 21.6 22.5 12.5 8.6 4.4 59.4 8.5 6.0 10.4 6.5 GMPR ENSG00000137198 "Guanosine monophosphate reductase" P36959 6 16238587-16295549 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 358.6;tongue: 205.0" "Cell type enhanced" "Detected in many" "Distal tubular cells: 86.1;Endometrial ciliated cells: 118.2;Erythroid cells: 367.1;Melanocytes: 92.5" "Cancer enhanced" "Detected in all" "melanoma: 95.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 14.9" "Group enriched" "Detected in all" 6 "granulocytes: 14.9;monocytes: 5.0;NK-cells: 9.6" "Cell line enhanced" "Detected in many" "HEL: 193.1;HMC-1: 314.7;SK-MEL-30: 74.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000904, HPA021476" Uncertain NA NA 950000 "Cluster 34: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" "HPA000904: AB_1078998, HPA021476: AB_1849858" "unprognostic (2.74e-1)" "unprognostic (1.05e-1)" "unprognostic (2.14e-1)" "unprognostic (4.97e-3)" "unprognostic (3.52e-2)" "unprognostic (1.05e-1)" "unprognostic (3.06e-1)" "prognostic favorable (8.07e-4)" "unprognostic (4.12e-1)" "prognostic favorable (2.06e-4)" "unprognostic (3.15e-1)" "unprognostic (2.86e-1)" "prognostic favorable (2.94e-5)" "unprognostic (3.01e-1)" "unprognostic (1.81e-1)" "unprognostic (7.31e-2)" "unprognostic (2.17e-1)" 10.0 23.3 28.5 2.8 31.9 29.7 6.5 32.4 21.6 6.6 35.7 15.5 2.7 13.3 16.5 5.3 56.9 3.7 101.7 19.6 38.2 25.5 5.9 9.1 2.5 36.8 45.6 38.0 18.3 14.2 24.9 7.8 35.0 63.1 3.4 2.2 21.5 9.0 358.6 12.4 6.0 9.9 39.7 12.5 36.5 52.3 41.3 6.5 4.4 205.0 1.6 5.2 3.7 33.2 0.0 0.0 0.3 0.0 2.7 2.1 0.1 3.9 15.7 27.2 55.2 1.6 0.4 0.0 8.8 6.0 19.1 0.1 6.7 0.8 4.5 0.0 5.0 193.1 0.1 0.0 11.8 0.8 314.7 3.7 2.8 8.5 0.0 22.2 49.5 0.7 43.9 0.3 4.8 3.8 0.2 4.1 2.0 0.2 7.5 0.0 41.9 0.0 36.1 5.4 9.4 1.2 1.9 3.2 74.4 12.1 3.0 1.4 12.5 0.4 0.2 1.3 7.5 2.3 0.0 0.0 0.9 20.3 21.8 14.9 3.3 0.4 0.7 5.0 1.2 0.2 0.1 0.5 1.5 1.5 0.0 0.2 3.3 9.6 1.7 1.5 0.0 16.0 28.5 31.9 32.4 21.6 19.6 38.2 36.8 45.6 35.0 39.7 41.3 33.2 4.6 0.0 0.0 8.8 1.3 5.1 30.2 0.7 0.6 0.7 5.3 3.8 52.8 35.8 2.7 20.2 0.0 25.3 0.6 1.4 86.1 12.4 16.0 118.2 8.7 6.8 7.8 367.1 3.8 4.9 2.8 10.2 9.2 78.9 55.3 38.9 17.9 5.0 8.9 0.0 11.5 3.2 4.1 6.4 2.1 16.3 34.5 47.4 92.5 2.8 9.2 9.8 2.1 3.0 1.7 3.0 1.2 80.9 1.4 69.9 2.2 15.5 6.4 0.8 0.0 12.6 7.4 6.5 17.2 1.3 1.8 6.8 3.5 19.4 3.8 8.3 GPR82 ENSG00000171657 "G protein-coupled receptor 82" Q96P67 X 41724181-41730130 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.7;lymphoid tissue: 6.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 16.5;Cone photoreceptor cells: 20.9;Kupffer cells: 37.0;Rod photoreceptor cells: 17.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 10 "eosinophil: 40.2;NK-cell: 10.9" "Group enriched" "Detected in many" 10 "granulocytes: 40.2;NK-cells: 10.9" "Cell line enriched" "Detected in single" 30 "HMC-1: 4.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA035914 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA035914: AB_10670671" "unprognostic (5.62e-3)" "unprognostic (1.81e-2)" "unprognostic (4.65e-2)" "unprognostic (3.88e-3)" "unprognostic (1.15e-2)" "unprognostic (3.28e-2)" "unprognostic (4.62e-4)" "unprognostic (1.41e-3)" "unprognostic (2.12e-2)" "unprognostic (5.00e-2)" "unprognostic (1.39e-1)" "unprognostic (3.01e-1)" "unprognostic (7.45e-2)" "unprognostic (2.37e-2)" "unprognostic (2.26e-1)" "unprognostic (8.00e-3)" "unprognostic (1.18e-1)" 0.1 0.9 0.7 2.3 0.5 0.1 0.6 0.8 0.7 0.3 0.4 1.1 1.7 0.3 0.1 0.4 0.3 0.6 0.1 0.5 1.0 0.3 0.7 0.2 3.2 1.4 0.7 0.2 0.1 0.2 0.1 0.0 0.7 0.2 1.1 0.0 0.4 0.4 0.0 0.4 2.7 0.3 0.6 1.1 0.9 0.0 1.3 0.5 0.3 0.0 6.9 0.8 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.4 40.2 0.0 2.5 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.3 10.9 2.4 0.0 0.0 0.2 0.7 0.5 0.8 0.7 0.5 1.0 1.4 0.7 0.7 0.6 1.3 0.8 0.7 0.0 7.2 2.0 5.5 4.7 5.2 2.8 0.6 16.5 1.2 0.3 0.4 4.3 5.9 1.8 20.9 0.9 3.7 3.1 0.0 2.0 0.2 1.0 3.4 3.1 1.2 0.8 1.7 1.1 0.2 2.9 1.5 1.4 0.0 1.4 3.3 1.3 1.3 13.5 2.2 2.0 2.0 37.0 7.7 0.2 4.1 13.9 3.6 0.0 3.4 1.7 12.3 10.6 1.1 2.8 5.1 3.0 1.3 3.6 6.9 0.3 1.1 17.2 0.0 3.4 2.3 1.6 1.1 0.3 2.7 0.7 12.6 3.9 3.4 3.8 GSDMA "FLJ39120, GSDM, GSDM1" ENSG00000167914 "Gasdermin A" Q96QA5 17 39953263-39977768 "Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skin 1: 58.9" "Group enriched" "Detected in some" 5 "Collecting duct cells: 3.7;Hofbauer cells: 5.0;Kupffer cells: 5.6;Macrophages: 2.6;Suprabasal keratinocytes: 2.7;Theca cells: 2.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 7.6" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HBEC3-KT: 4.1;hTCEpi: 2.7;hTERT-HME1: 5.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023313, HPA064826" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA 44000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA023313: AB_1850378, HPA064826: AB_2685361" "unprognostic (1.32e-2)" "unprognostic (2.01e-1)" "unprognostic (2.95e-2)" "unprognostic (1.06e-1)" "unprognostic (3.62e-1)" "unprognostic (1.97e-1)" "unprognostic (7.77e-2)" "unprognostic (1.39e-1)" "unprognostic (3.24e-1)" "unprognostic (3.52e-2)" "unprognostic (2.71e-1)" "unprognostic (2.90e-2)" "unprognostic (1.06e-2)" "unprognostic (9.86e-2)" "unprognostic (7.45e-2)" "unprognostic (3.63e-2)" "unprognostic (3.79e-2)" 3.4 0.7 0.2 0.9 0.2 0.4 3.5 0.4 0.4 0.8 0.2 0.7 0.6 0.4 6.6 3.2 0.3 0.8 0.3 0.3 0.2 0.3 0.3 0.4 0.7 0.4 0.0 0.1 0.3 1.3 0.1 1.6 0.4 0.1 1.2 0.0 0.8 0.0 0.4 58.9 0.5 0.6 0.0 0.2 0.3 0.3 0.4 0.5 0.1 0.1 3.4 1.1 1.5 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.2 0.5 0.4 0.2 0.0 0.1 0.8 0.0 2.7 0.5 5.4 0.0 0.0 0.0 0.1 1.3 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.9 0.1 0.1 2.2 0.0 2.6 0.0 1.3 0.8 0.1 0.1 0.6 0.9 0.7 0.1 0.1 0.2 0.5 0.5 0.2 0.2 0.4 0.4 0.3 0.2 0.4 0.0 0.4 0.0 0.4 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 3.7 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.7 0.0 5.0 0.0 0.1 0.7 0.0 5.6 0.6 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.7 0.0 0.2 2.8 0.0 0.0 HCLS1 "CTTNL, HS1" ENSG00000180353 "Hematopoietic cell-specific Lyn substrate 1" P14317 3 121631399-121660927 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 153.6;lymphoid tissue: 300.3" "Cell type enhanced" "Detected in many" "B-cells: 175.7;Kupffer cells: 666.3;Macrophages: 269.0;monocytes: 245.7;NK-cells: 216.3;T-cells: 181.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 265.6;HMC-1: 362.3;RPMI-8226: 256.5;THP-1: 262.8;U-266/70: 361.6;U-698: 371.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019143 Enhanced Supported "Plasma membrane,Cytosol" NA NA 870000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA019143: AB_1850532" "unprognostic (2.27e-2)" "unprognostic (1.79e-3)" "unprognostic (5.38e-3)" "unprognostic (6.29e-2)" "unprognostic (1.01e-2)" "unprognostic (4.02e-3)" "unprognostic (2.35e-1)" "unprognostic (4.88e-3)" "unprognostic (1.70e-2)" "unprognostic (1.19e-1)" "unprognostic (6.76e-2)" "unprognostic (2.28e-1)" "unprognostic (1.03e-3)" "unprognostic (2.93e-1)" "unprognostic (3.46e-2)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" 67.0 32.9 14.6 147.2 14.7 153.6 25.5 15.4 18.7 20.7 15.8 29.2 21.2 13.7 6.4 15.7 21.5 37.8 18.4 14.3 17.0 21.5 39.1 52.7 207.6 21.6 17.5 9.4 11.9 7.7 14.6 51.4 20.8 15.8 31.4 2.3 16.0 11.1 7.3 11.1 68.7 34.6 18.5 300.3 27.1 4.5 18.2 140.3 15.4 18.8 242.8 53.0 13.7 23.0 0.8 0.0 0.2 0.1 20.9 11.5 5.7 4.1 4.0 0.8 1.6 0.1 0.0 265.6 124.6 0.0 0.2 0.3 6.9 9.9 1.1 120.6 0.0 172.6 0.0 0.0 11.6 192.4 362.3 2.2 0.5 0.0 1.5 0.0 153.4 106.2 35.1 235.9 0.0 0.0 137.9 162.9 0.3 0.2 4.5 137.1 0.2 256.5 0.0 68.0 0.3 0.2 0.2 0.4 0.6 0.6 0.1 262.8 203.5 0.0 2.0 0.3 0.9 361.6 118.1 371.5 1.9 181.5 0.2 357.3 713.1 1180.9 405.3 870.4 333.0 345.7 334.2 376.8 636.2 313.1 279.3 326.2 1619.2 280.0 997.1 197.4 494.2 1427.9 14.6 14.7 15.4 18.7 14.3 17.0 21.6 17.5 20.8 18.5 18.2 23.0 23.0 9.6 31.8 1.0 175.7 3.2 1.0 7.8 0.6 0.5 2.7 5.1 2.3 4.3 13.1 0.0 0.0 122.4 139.5 0.8 0.0 0.3 1.1 8.8 1.6 23.3 0.0 50.5 1.4 0.2 60.0 7.0 8.6 3.1 73.4 0.7 27.8 7.7 126.9 0.0 0.7 0.4 4.1 666.3 105.8 1.5 3.4 269.0 19.6 26.2 245.7 0.4 216.3 0.5 0.3 0.2 0.2 1.2 148.6 0.4 0.1 0.9 24.7 0.8 13.1 3.7 6.7 0.6 0.6 1.3 4.4 145.4 181.4 2.4 0.5 2.2 IGSF21 "MGC15730, RP11-121A23.1" ENSG00000117154 "Immunoglobin superfamily member 21" Q96ID5 1 18107798-18378483 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 51.7" "Group enriched" "Detected in some" 4 "Bipolar cells: 177.8;Excitatory neurons: 82.2;Microglial cells: 74.9;Oligodendrocyte precursor cells: 141.3" "Group enriched" "Detected in many" 5 "breast cancer: 4.1;glioma: 8.6;prostate cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 19.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 23000 "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.87e-1)" "unprognostic (1.73e-1)" "unprognostic (1.50e-3)" "unprognostic (7.06e-2)" "unprognostic (3.29e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "unprognostic (1.66e-2)" "unprognostic (7.87e-2)" "unprognostic (2.77e-3)" "unprognostic (4.34e-2)" "unprognostic (2.33e-1)" "unprognostic (7.85e-4)" "unprognostic (3.76e-5)" "unprognostic (2.10e-1)" "unprognostic (1.23e-2)" "unprognostic (2.63e-2)" 2.2 4.8 29.6 0.4 35.8 0.4 3.0 41.4 51.7 1.7 9.2 1.0 0.0 1.0 0.4 0.9 1.0 0.8 1.0 37.4 17.6 1.1 0.4 1.5 0.2 26.9 23.4 0.6 1.9 10.4 1.6 1.4 27.0 3.8 0.3 9.4 1.1 1.1 0.3 0.8 0.4 0.3 21.6 13.0 0.6 0.8 24.5 0.8 0.6 0.4 0.7 3.9 1.1 33.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.6 35.8 41.4 51.7 37.4 17.6 26.9 23.4 27.0 21.6 24.5 33.5 0.1 0.0 0.0 3.6 0.6 0.3 0.2 0.0 0.0 177.8 9.2 2.7 0.6 1.5 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 5.9 0.0 0.0 1.8 3.0 0.0 82.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.7 28.9 0.1 0.0 23.6 4.0 12.8 0.6 12.8 0.0 74.9 0.0 6.3 0.0 141.3 2.4 0.1 1.3 0.0 0.0 0.9 0.0 0.0 0.0 13.0 6.6 4.5 0.2 0.4 0.6 0.0 0.1 0.0 0.0 0.0 0.2 0.2 ITGB2 "CD18, LFA-1, MAC-1, MFI7" ENSG00000160255 "Integrin subunit beta 2" P05107 21 44885953-44931989 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 376.2;lymphoid tissue: 175.2" "Group enriched" "Detected in many" 6 "dendritic cells: 417.6;Hofbauer cells: 652.4;Kupffer cells: 485.9;Langerhans cells: 259.1;Macrophages: 527.4;monocytes: 463.8;NK-cells: 959.9;T-cells: 254.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "THP-1: 812.4;U-937: 615.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008877, HPA016894" Enhanced Supported "Plasma membrane,Rods & Rings" NA NA 3300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Rods & Rings" "HPA008877: AB_1846256, HPA016894: AB_1846257" "unprognostic (1.94e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (6.21e-3)" "unprognostic (2.95e-2)" "unprognostic (9.73e-3)" "unprognostic (2.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.18e-2)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.87e-3)" "unprognostic (1.42e-1)" "unprognostic (4.42e-2)" "unprognostic (2.65e-2)" "unprognostic (4.83e-2)" 54.5 23.2 8.2 175.2 9.5 376.2 15.4 13.1 9.3 15.5 11.7 25.2 23.8 8.5 2.8 16.2 17.0 36.4 11.8 7.7 14.2 8.4 23.4 78.0 169.1 29.5 19.9 7.2 11.3 5.1 4.6 44.4 28.1 8.8 13.9 1.1 19.5 9.2 6.8 9.3 32.8 46.4 23.9 137.2 29.1 5.9 26.2 87.2 7.3 7.6 68.4 46.3 5.9 50.4 1.9 4.8 0.0 0.0 0.0 0.3 1.7 0.0 2.7 0.1 0.0 0.4 0.4 17.9 128.1 0.2 0.6 0.5 0.0 0.2 0.0 1.5 1.4 18.2 0.0 3.2 0.1 106.6 27.5 1.6 0.1 0.5 0.3 0.1 0.3 58.0 0.7 1.4 7.0 4.0 117.8 126.1 0.4 0.4 2.4 1.5 23.2 64.6 4.7 0.0 0.6 1.3 3.4 2.5 1.7 0.0 0.4 812.4 2.5 0.2 6.6 0.4 3.7 0.8 5.9 2.9 0.1 615.0 0.9 186.6 1848.8 1224.1 726.7 1144.9 326.6 86.1 349.7 506.5 1031.4 115.2 233.1 396.5 1386.1 585.5 1183.5 165.5 288.0 3034.2 8.2 9.5 13.1 9.3 7.7 14.2 29.5 19.9 28.1 23.9 26.2 50.4 7.1 16.0 29.6 0.3 81.7 5.5 0.5 9.6 0.6 0.0 4.1 6.5 4.0 14.3 18.6 5.5 0.0 4.0 417.6 0.3 0.0 3.4 1.0 0.6 0.5 16.8 0.0 19.6 0.5 0.4 4.8 5.3 2.6 0.7 24.1 8.2 9.7 8.6 652.4 0.0 0.3 0.2 2.0 485.9 259.1 2.8 0.6 527.4 5.4 27.2 463.8 0.4 959.9 0.0 0.2 0.6 0.1 1.5 50.5 0.6 1.8 4.2 3.6 0.8 6.6 2.1 3.2 0.2 1.0 0.9 5.1 5.6 254.5 0.0 0.3 0.7 LAPTM5 ENSG00000162511 "Lysosomal protein transmembrane 5" Q13571 1 30732469-30757774 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1285.7;lymphoid tissue: 672.2" "Group enriched" "Detected in many" 4 "B-cells: 872.9;dendritic cells: 340.2;granulocytes: 639.8;Hofbauer cells: 1150.4;Kupffer cells: 942.2;Langerhans cells: 489.6;Macrophages: 925.0;monocytes: 446.1;NK-cells: 562.3;T-cells: 432.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 554.0;HEL: 1053.2;HL-60: 676.4;HMC-1: 2382.4;REH: 785.2;U-698: 898.1;U-937: 542.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051293 Approved Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Cytosol "HPA051293: AB_2681424" "unprognostic (3.12e-2)" "prognostic favorable (3.40e-4)" "unprognostic (6.86e-2)" "unprognostic (4.05e-3)" "unprognostic (1.63e-1)" "unprognostic (8.45e-2)" "unprognostic (1.43e-1)" "unprognostic (3.76e-1)" "unprognostic (1.22e-3)" "unprognostic (2.30e-1)" "unprognostic (6.75e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (5.89e-5)" "unprognostic (9.47e-2)" "unprognostic (8.18e-3)" "unprognostic (5.98e-2)" "unprognostic (3.94e-2)" 144.7 82.1 47.6 443.0 49.7 1285.7 60.4 49.7 90.4 53.1 55.7 82.2 68.1 27.3 16.7 49.5 46.8 137.9 31.6 45.2 62.7 30.5 98.6 284.9 672.2 82.4 67.3 16.4 30.2 21.8 22.6 145.2 75.8 31.5 90.6 5.9 38.5 30.9 9.2 24.0 155.9 93.5 69.2 491.1 72.9 10.9 81.1 298.3 38.5 20.9 636.5 161.1 22.8 114.9 1.2 0.0 1.7 0.0 0.1 0.1 0.6 0.9 0.3 0.5 0.1 0.7 1.2 554.0 56.0 1.7 1.9 2.2 0.0 0.8 0.5 62.3 0.0 1053.2 0.0 1.6 0.9 676.4 2382.4 0.6 1.2 0.6 4.1 0.3 124.2 70.7 13.8 34.0 8.8 0.0 117.5 142.2 0.7 0.0 0.0 785.2 99.6 391.6 0.8 0.1 0.6 0.4 1.3 1.3 1.1 1.0 0.5 422.2 145.3 0.6 3.0 0.6 3.4 2.7 0.7 898.1 3.1 542.8 1.8 1094.2 1522.8 1446.7 538.5 1046.1 616.3 823.6 485.5 502.8 825.7 1089.4 481.2 481.2 1709.5 327.0 1075.7 392.7 656.9 2740.4 47.6 49.7 49.7 90.4 45.2 62.7 82.4 67.3 75.8 69.2 81.1 114.9 62.9 25.6 100.4 0.0 872.9 23.8 1.1 1.3 4.0 0.0 6.2 10.4 5.5 14.3 13.9 3.7 0.0 5.8 340.2 0.8 0.0 1.2 2.0 1.4 0.9 60.2 1.2 78.2 0.2 0.7 8.4 12.3 10.2 1.1 639.8 0.2 47.2 9.4 1150.4 0.0 0.8 0.9 0.0 942.2 489.6 4.9 1.5 925.0 49.8 43.1 446.1 0.3 562.3 0.5 0.5 1.4 0.2 0.4 144.8 0.9 0.5 3.0 11.4 1.3 0.0 4.1 5.6 0.3 1.1 1.8 20.0 8.9 432.7 18.2 2.4 1.9 LILRA2 "CD85h, ILT1, LIR-7, LIR7" ENSG00000239998 "Leukocyte immunoglobulin like receptor A2" Q8N149 19 54572920-54590287 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.5;lymphoid tissue: 57.4" "Group enriched" "Detected in some" 5 "Hofbauer cells: 22.0;Kupffer cells: 79.9;Macrophages: 39.1;monocytes: 48.7" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 31.6" "Group enriched" "Detected in many" 6 "granulocytes: 31.6;monocytes: 11.6" "Cell line enhanced" "Detected in some" "NB-4: 1.7;REH: 2.0;THP-1: 4.0;U-937: 9.1" "Secreted to blood" NA NA 140000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (2.04e-1)" "unprognostic (7.72e-2)" "unprognostic (6.94e-2)" "unprognostic (1.78e-1)" "unprognostic (1.54e-2)" "unprognostic (2.65e-2)" "unprognostic (8.45e-2)" "unprognostic (3.56e-2)" "unprognostic (1.22e-1)" "unprognostic (3.53e-5)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (5.43e-2)" "unprognostic (5.58e-2)" "unprognostic (3.30e-4)" "unprognostic (4.21e-2)" "unprognostic (6.59e-2)" 5.2 3.2 0.9 2.8 1.0 15.5 1.8 1.0 1.5 0.9 0.9 1.5 0.2 1.0 0.2 0.9 4.0 0.4 1.9 1.0 1.0 1.4 3.4 10.3 0.2 2.0 1.2 0.8 1.4 0.1 0.8 0.1 2.0 1.4 0.2 0.2 1.7 0.1 0.5 0.7 1.7 0.4 1.1 57.4 1.6 0.8 1.6 0.2 0.8 0.2 0.3 2.2 1.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 2.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.1 0.0 5.3 7.6 3.0 0.1 11.6 0.1 0.1 0.1 0.1 3.3 0.3 0.1 0.1 31.6 0.4 11.3 0.7 0.1 6.1 0.9 1.0 1.0 1.5 1.0 1.0 2.0 1.2 2.0 1.1 1.6 1.8 0.2 3.2 3.0 0.0 0.3 0.3 1.6 0.0 0.0 0.9 0.4 0.1 0.5 1.5 1.8 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.8 0.0 0.2 0.2 0.6 0.0 0.1 6.3 0.1 0.4 0.4 22.0 0.0 0.0 0.0 0.0 79.9 5.9 0.6 0.0 39.1 0.0 8.4 48.7 0.0 2.1 0.0 0.1 0.0 0.0 0.0 1.1 1.0 0.0 0.1 1.5 0.6 0.0 2.1 0.3 0.3 0.3 0.0 0.1 0.4 1.4 0.0 0.0 0.6 LILRB4 "CD85k, HM18, ILT3, LIR-5, LIR5" ENSG00000186818 "Leukocyte immunoglobulin like receptor B4" Q8NHJ6 19 54643889-54670359 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 13.7;lymphoid tissue: 18.8" "Cell type enhanced" "Detected in some" "dendritic cells: 76.9;Hofbauer cells: 127.6;Kupffer cells: 118.9;Macrophages: 104.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 37.3" "Group enriched" "Detected in many" 44 "dendritic cells: 37.3;monocytes: 10.8" "Cell line enriched" "Detected in some" 32 "Karpas-707: 407.8" HPA052807 Approved NA NA 11000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA052807: AB_2681958" "unprognostic (4.09e-2)" "unprognostic (5.75e-3)" "unprognostic (6.06e-2)" "unprognostic (1.91e-2)" "unprognostic (1.82e-1)" "unprognostic (1.55e-1)" "unprognostic (5.03e-2)" "unprognostic (3.53e-1)" "unprognostic (4.13e-2)" "unprognostic (1.52e-1)" "unprognostic (5.43e-1)" "unprognostic (2.79e-1)" "unprognostic (1.91e-2)" "unprognostic (1.08e-1)" "unprognostic (4.42e-2)" "unprognostic (4.51e-2)" "unprognostic (4.52e-2)" 8.6 4.6 2.2 10.9 2.5 2.0 3.6 2.7 4.2 1.1 2.2 4.1 1.6 0.9 0.3 1.0 4.0 1.7 2.3 2.2 2.8 2.2 2.9 13.7 11.4 3.8 3.2 0.7 1.6 0.1 2.2 1.4 3.5 1.9 2.3 0.1 3.6 0.3 0.5 0.5 6.3 0.7 3.2 18.8 1.7 0.3 3.0 0.6 2.4 0.0 2.1 6.1 0.8 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 407.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 1.4 12.8 0.0 0.2 0.0 0.4 0.0 7.8 0.0 0.0 10.8 0.0 0.2 0.0 0.0 11.7 0.5 0.0 0.0 0.1 0.1 8.9 37.3 0.0 3.8 2.2 2.5 2.7 4.2 2.2 2.8 3.8 3.2 3.5 3.2 3.0 3.3 0.6 0.0 4.1 0.0 13.4 0.4 0.0 0.0 0.0 0.2 0.3 1.7 1.0 1.5 1.3 0.0 0.0 0.3 76.9 0.1 0.0 0.0 0.2 0.0 0.0 4.2 0.0 7.8 0.1 0.0 0.9 0.5 0.0 0.0 1.3 0.0 2.2 0.8 127.6 0.0 0.2 0.0 0.0 118.9 12.6 0.6 0.0 104.0 1.8 14.0 29.3 0.2 1.0 0.0 0.0 0.1 0.0 0.0 24.3 0.0 0.0 0.0 0.0 0.2 6.6 0.2 0.1 0.0 0.4 0.1 0.1 0.8 2.2 0.0 0.2 0.1 LRRC25 "FLJ38116, MAPA" ENSG00000175489 "Leucine rich repeat containing 25" Q8N386 19 18391137-18397622 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 32.4;lymphoid tissue: 61.2" "Group enriched" "Detected in some" 6 "Hofbauer cells: 47.0;Kupffer cells: 123.6;Macrophages: 90.0;monocytes: 74.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 320.6;eosinophil: 356.2;intermediate monocyte: 512.1;myeloid DC: 229.3;neutrophil: 573.0;non-classical monocyte: 706.7" "Group enriched" "Detected in all" 60 "dendritic cells: 229.3;granulocytes: 573.0;monocytes: 706.7" "Cell line enhanced" "Detected in some" "Hep G2: 1.0;HMC-1: 1.8;THP-1: 1.7;U-937: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029459 Approved Approved "Endoplasmic reticulum,Microtubules,Cytosol" NA NA 630000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Endoplasmic reticulum, Microtubules, Cytosol" "HPA029459: AB_10610005" "unprognostic (2.72e-2)" "unprognostic (6.08e-2)" "unprognostic (1.76e-2)" "unprognostic (2.07e-1)" "unprognostic (3.77e-2)" "unprognostic (9.15e-2)" "unprognostic (5.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-2)" "unprognostic (4.63e-2)" "unprognostic (2.02e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-3)" "unprognostic (5.77e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (1.74e-1)" "unprognostic (1.14e-1)" 9.4 9.4 2.4 21.8 2.5 32.4 3.1 3.3 2.9 1.8 3.2 3.3 3.7 1.6 0.7 2.3 3.9 5.3 2.5 2.3 3.1 2.4 5.9 11.5 9.9 4.6 4.0 1.5 2.0 0.7 1.2 5.4 4.2 2.0 2.8 0.3 2.6 1.2 3.7 1.0 4.8 6.7 2.8 61.2 2.3 1.2 5.4 3.0 1.2 8.7 4.0 7.0 1.3 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.3 1.0 0.8 0.4 1.8 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.4 0.2 0.1 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.7 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.2 1.5 0.1 55.4 320.6 356.2 0.9 512.1 1.9 7.3 0.6 0.7 229.3 8.4 0.5 0.6 573.0 4.6 706.7 32.1 1.3 229.2 2.4 2.5 3.3 2.9 2.3 3.1 4.6 4.0 4.2 2.8 5.4 4.7 0.7 0.0 1.3 0.0 5.0 0.0 0.1 0.1 0.0 0.1 0.3 1.0 0.3 0.0 0.7 0.0 0.0 0.1 2.9 0.1 5.9 0.1 1.9 0.2 0.1 0.9 0.0 2.1 0.1 0.0 0.4 0.5 0.0 0.4 10.2 0.0 1.8 0.5 47.0 0.0 0.1 0.0 0.0 123.6 12.5 0.5 0.0 90.0 1.8 1.0 74.9 0.0 6.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 2.4 0.2 0.0 0.2 0.0 0.1 0.4 1.1 0.2 0.1 0.1 LY86 "dJ80N2.1, MD-1" ENSG00000112799 "Lymphocyte antigen 86" O95711 6 6588108-6654983 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 78.4" "Group enriched" "Detected in many" 9 "B-cells: 124.9;Hofbauer cells: 191.7;Kupffer cells: 199.1;Langerhans cells: 118.6;Macrophages: 149.8;Microglial cells: 105.9;monocytes: 155.6" "Cancer enhanced" "Detected in all" "glioma: 22.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 426.6;myeloid DC: 426.1" "Group enriched" "Detected in all" 43 "B-cells: 335.1;dendritic cells: 426.1;monocytes: 426.6" "Cell line enhanced" "Detected in some" "Daudi: 69.5;NB-4: 44.7;RPMI-8226: 245.0;THP-1: 103.8;U-937: 45.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025000, HPA044895" Approved "Secreted to blood" NA NA 77000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" "CAB025000: , HPA044895: AB_2679138" "unprognostic (1.82e-1)" "unprognostic (2.49e-3)" "unprognostic (2.01e-2)" "unprognostic (7.88e-2)" "unprognostic (2.15e-1)" "unprognostic (1.93e-1)" "unprognostic (2.53e-1)" "unprognostic (1.46e-3)" "unprognostic (3.52e-2)" "unprognostic (3.17e-1)" "unprognostic (1.69e-1)" "unprognostic (1.16e-1)" "unprognostic (5.82e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (5.61e-4)" "unprognostic (1.11e-1)" "unprognostic (4.20e-2)" 9.7 10.3 14.0 30.9 13.5 29.2 7.4 14.7 22.0 8.2 14.2 7.6 4.9 3.8 2.8 3.1 4.3 14.6 2.9 13.5 15.8 3.1 13.3 29.7 72.1 17.8 15.4 3.3 3.0 3.4 2.3 14.5 18.7 3.8 11.1 1.2 5.5 6.2 0.7 3.4 16.8 11.1 17.8 52.7 6.2 1.8 18.0 15.1 1.5 1.1 78.4 15.6 1.1 24.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 44.7 0.0 0.0 0.0 8.0 0.0 245.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 103.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 30.3 0.0 45.8 0.0 4.1 426.6 3.5 1.0 234.9 0.7 335.1 1.1 1.1 426.1 248.8 4.7 2.7 9.1 5.3 88.3 16.3 1.8 221.1 14.0 13.5 14.7 22.0 13.5 15.8 17.8 15.4 18.7 17.8 18.0 24.8 1.2 0.0 15.0 1.6 124.9 2.0 0.0 0.0 0.0 0.0 0.9 3.7 1.5 1.5 1.3 0.0 0.0 1.4 9.8 0.0 0.0 0.0 3.4 0.4 0.1 5.4 0.0 3.8 3.8 0.0 1.8 2.1 0.0 0.0 1.3 0.0 4.2 1.3 191.7 0.0 0.6 0.3 0.0 199.1 118.6 15.4 0.3 149.8 0.0 105.9 155.6 0.0 4.1 0.5 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.7 0.4 6.6 0.4 0.2 5.3 0.2 0.3 2.4 1.9 3.6 0.0 0.2 0.2 MFSD1 "FLJ14153, Minerva, UG0581B09" ENSG00000118855 "Major facilitator superfamily domain containing 1" Q9H3U5 3 158732198-158829719 "Predicted intracellular proteins, Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 214.4;Kupffer cells: 289.7;Macrophages: 212.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 254.5;granulocytes: 246.0;monocytes: 288.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065858 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" Cytosol "HPA065858: AB_2685569" "unprognostic (9.94e-2)" "unprognostic (3.12e-3)" "unprognostic (3.54e-2)" "unprognostic (1.00e-1)" "unprognostic (2.16e-2)" "unprognostic (7.37e-2)" "unprognostic (1.28e-2)" "unprognostic (2.61e-2)" "unprognostic (2.52e-1)" "unprognostic (1.15e-1)" "unprognostic (6.48e-2)" "unprognostic (2.92e-1)" "prognostic favorable (5.60e-5)" "unprognostic (1.62e-1)" "unprognostic (6.33e-3)" "unprognostic (4.66e-2)" "unprognostic (2.57e-1)" 39.7 27.4 11.0 38.1 12.9 35.9 26.9 20.2 15.8 22.5 23.8 31.1 25.7 16.1 19.4 35.0 21.4 32.3 17.2 15.7 14.5 30.3 39.5 40.5 34.5 15.8 12.2 17.9 31.5 36.0 7.5 30.7 16.4 26.8 22.2 8.4 48.4 23.4 11.1 23.4 23.2 26.2 11.5 42.0 36.1 18.0 16.1 16.1 27.9 16.9 21.5 40.0 19.6 17.3 83.3 28.9 9.1 26.3 51.0 45.0 35.9 109.7 61.8 46.5 45.9 10.3 82.8 19.7 73.5 81.9 24.1 37.0 22.0 26.7 40.9 68.2 33.7 57.2 24.0 6.7 52.1 206.0 135.7 59.3 38.5 39.7 9.5 15.9 38.0 14.0 39.9 32.9 85.1 19.2 11.3 83.2 8.5 29.9 50.9 19.8 11.3 170.9 18.1 16.3 18.2 29.8 76.7 70.0 25.0 8.3 56.9 100.1 102.8 58.6 23.2 87.3 60.5 98.3 94.4 9.6 74.1 162.0 39.7 102.4 288.8 246.0 36.6 223.4 35.3 54.2 30.3 33.9 254.5 44.5 32.2 35.5 97.1 32.9 187.8 81.8 38.9 252.1 11.0 12.9 20.2 15.8 15.7 14.5 15.8 12.2 16.4 11.5 16.1 17.3 28.5 19.2 34.0 12.1 39.6 21.4 46.2 38.4 33.0 11.8 33.3 19.7 22.2 20.0 51.6 22.0 6.2 27.5 24.1 33.3 19.6 34.0 5.3 13.6 22.7 28.2 22.8 56.0 14.6 28.5 33.6 33.7 23.9 17.2 48.8 8.9 37.1 34.4 214.4 18.5 15.2 28.6 34.6 289.7 90.7 6.7 12.2 212.3 32.0 16.9 88.7 26.0 25.7 15.1 29.4 29.0 29.9 11.3 32.9 30.0 27.1 31.8 59.3 10.5 13.1 11.8 23.8 11.6 8.7 61.2 26.0 56.0 22.3 19.4 28.3 58.4 MPEG1 MPG1 ENSG00000197629 "Macrophage expressed 1" Q2M385 11 59208510-59212927 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 207.4" "Group enriched" "Detected in some" 4 "dendritic cells: 156.0;Kupffer cells: 409.8;Macrophages: 174.6;monocytes: 218.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 290.5;intermediate monocyte: 209.9;myeloid DC: 144.7;non-classical monocyte: 245.2;plasmacytoid DC: 204.9" "Group enriched" "Detected in many" 6 "dendritic cells: 204.9;monocytes: 290.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA046801 Approved "Secreted to blood" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA046801: AB_2679814" "unprognostic (1.24e-1)" "unprognostic (2.17e-3)" "unprognostic (1.05e-2)" "unprognostic (2.00e-2)" "unprognostic (3.38e-2)" "unprognostic (2.79e-3)" "unprognostic (7.82e-2)" "unprognostic (1.41e-2)" "unprognostic (6.23e-2)" "unprognostic (2.76e-1)" "unprognostic (5.48e-2)" "unprognostic (3.51e-1)" "unprognostic (1.48e-1)" "unprognostic (9.38e-2)" "unprognostic (2.48e-2)" "unprognostic (1.76e-1)" "unprognostic (5.86e-2)" 29.2 15.8 1.5 112.4 1.6 21.3 13.5 1.7 2.4 11.6 3.2 32.9 40.9 10.9 3.7 12.6 6.9 36.2 10.3 1.4 2.1 6.0 41.1 35.4 96.3 3.3 1.9 4.9 4.6 4.6 1.6 35.8 2.5 8.0 43.4 0.3 7.3 9.3 3.9 7.1 52.8 28.2 2.9 207.4 19.2 4.5 4.0 42.8 5.9 8.3 75.2 42.7 2.1 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 290.5 8.4 0.5 209.9 0.5 12.6 0.3 0.2 144.7 14.0 0.2 0.1 38.5 1.2 245.2 204.9 0.6 214.5 1.5 1.6 1.7 2.4 1.4 2.1 3.3 1.9 2.5 2.9 4.0 4.0 0.7 0.0 7.9 0.0 33.8 1.1 0.0 0.0 1.2 0.0 0.3 0.9 1.7 1.5 0.6 0.0 0.0 0.3 156.0 0.1 0.0 0.0 0.2 0.0 0.1 1.7 0.0 4.4 0.0 0.0 0.6 0.8 0.5 0.1 2.5 0.0 4.6 3.7 52.4 0.0 0.0 0.0 0.0 409.8 48.0 0.6 0.0 174.6 1.8 10.3 218.2 0.2 7.2 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.7 0.7 0.1 6.6 0.7 0.4 0.0 0.0 0.3 1.6 0.3 2.7 0.0 0.0 0.1 MRC1 "bA541I19.1, CD206, CLEC13D, CLEC13DL, MRC1L1" ENSG00000260314 "Mannose receptor C-type 1" P22897 10 17809348-17911164 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Endocytosis, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 122.3" "Group enriched" "Detected in many" 4 "Breast glandular cells: 128.9;Hepatic stellate cells: 397.7;Hofbauer cells: 176.1;Kupffer cells: 361.4;Macrophages: 316.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 16 "myeloid DC: 4.8" "Lineage enriched" "Detected in single" 16 "dendritic cells: 4.8" "Group enriched" "Detected in some" 19 "MOLT-4: 19.3;TIME: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004114, HPA045134, CAB068203" Enhanced NA NA 170000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "CAB068203: AB_2665652, HPA004114: AB_1846270, HPA045134: AB_2679228" "unprognostic (2.20e-1)" "unprognostic (2.07e-1)" "unprognostic (1.03e-2)" "unprognostic (2.58e-1)" "unprognostic (5.62e-2)" "unprognostic (4.30e-1)" "unprognostic (6.36e-3)" "unprognostic (1.35e-1)" "unprognostic (1.05e-2)" "unprognostic (6.05e-2)" "unprognostic (5.61e-2)" "unprognostic (4.12e-1)" "unprognostic (2.94e-2)" "unprognostic (4.97e-2)" "unprognostic (3.05e-2)" "unprognostic (1.74e-2)" "unprognostic (7.02e-2)" 54.4 28.7 0.8 24.0 1.7 0.7 16.3 0.3 3.5 17.2 9.2 16.1 9.9 7.2 1.7 13.1 11.9 27.7 10.2 1.1 0.7 7.6 40.9 122.3 15.2 1.4 0.9 6.2 8.1 4.6 1.5 54.3 1.1 2.2 18.5 0.1 4.9 8.0 1.8 2.8 17.5 30.3 0.7 50.6 9.7 7.5 2.8 8.0 5.5 8.7 3.0 29.0 2.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 19.3 0.0 0.2 0.0 0.0 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 17.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.8 1.7 0.3 3.5 1.1 0.7 1.4 0.9 1.1 0.7 2.8 1.3 4.0 32.1 43.5 1.3 3.5 0.4 0.0 0.0 0.0 0.0 128.9 1.7 3.6 11.5 7.4 0.0 0.0 0.9 1.0 1.4 0.0 0.1 27.3 0.0 0.1 39.0 0.0 3.2 0.8 0.4 1.4 2.5 0.0 0.1 13.9 0.1 397.7 13.1 176.1 0.0 1.3 0.9 0.0 361.4 46.8 19.4 1.5 316.5 0.0 60.9 0.5 0.0 0.0 0.5 0.5 0.1 1.5 0.0 1.0 0.0 2.2 0.1 5.8 0.0 32.9 3.0 2.2 0.4 2.3 1.2 0.4 2.1 4.7 1.7 0.8 0.1 MS4A4E ENSG00000214787 "Membrane spanning 4-domains A4E" Q96PG1 11 60200270-60243137 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "dendritic cells: 1.4;Erythroid cells: 1.3;Kupffer cells: 3.4;Macrophages: 5.4;Microglial cells: 1.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 17.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 17.8" "Cell line enhanced" "Detected in many" "HMC-1: 8.1" HPA040075 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA040075: AB_10793915" "unprognostic (1.90e-1)" "unprognostic (2.64e-2)" "unprognostic (7.05e-2)" "unprognostic (9.42e-2)" "unprognostic (5.99e-2)" "unprognostic (1.45e-2)" "unprognostic (8.97e-2)" "unprognostic (1.23e-3)" "unprognostic (3.33e-2)" "unprognostic (1.74e-1)" "unprognostic (1.28e-3)" "unprognostic (4.16e-2)" "unprognostic (9.88e-3)" "unprognostic (4.97e-2)" "unprognostic (4.38e-2)" "unprognostic (1.07e-2)" "unprognostic (4.05e-2)" 5.9 4.0 5.4 3.5 5.1 7.7 3.7 8.1 6.7 1.1 6.5 2.8 3.3 1.8 2.8 1.6 1.5 3.0 1.3 6.0 4.7 1.8 5.5 2.9 2.8 5.4 4.1 1.6 1.5 1.3 0.0 1.8 4.6 2.0 2.7 4.5 1.7 1.2 4.4 4.2 4.5 2.9 2.6 4.7 2.7 2.9 5.3 1.1 1.2 0.8 1.9 1.5 0.0 5.8 4.2 1.7 0.9 2.2 0.7 0.4 3.2 1.7 0.2 0.2 0.3 1.2 1.8 1.3 1.7 0.1 1.2 3.4 0.3 0.2 0.3 5.0 1.1 2.3 3.5 2.0 0.6 1.3 8.1 0.5 1.5 0.5 0.7 0.9 0.2 1.8 2.4 4.2 0.2 1.6 1.9 2.6 1.8 2.0 1.3 1.6 1.7 1.8 0.5 2.1 1.3 2.2 4.9 1.8 2.4 2.0 2.4 2.4 1.1 1.7 7.8 4.8 1.6 5.6 4.7 1.9 0.9 2.8 1.5 17.8 1.4 0.2 0.4 1.6 0.3 0.5 0.3 0.2 2.5 0.7 0.3 0.4 2.7 0.9 1.4 1.4 0.2 0.3 5.4 5.1 8.1 6.7 6.0 4.7 5.4 4.1 4.6 2.6 5.3 5.8 0.1 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.6 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.2 0.0 0.0 3.4 0.0 0.0 0.0 5.4 0.0 1.9 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MS4A6A "CD20L3, MS4A6" ENSG00000110077 "Membrane spanning 4-domains A6A" Q9H2W1 11 60172014-60184666 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 580.8;Hofbauer cells: 376.8;Kupffer cells: 1649.6;Langerhans cells: 470.0;Macrophages: 675.9;monocytes: 429.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 406.4;classical monocyte: 1095.3;intermediate monocyte: 345.6;myeloid DC: 638.8;plasmacytoid DC: 454.4" "Group enriched" "Detected in all" 74 "dendritic cells: 638.8;granulocytes: 406.4;monocytes: 1095.3" "Cell line enriched" "Detected in some" 8 "THP-1: 47.9" "HPA011391, HPA076623" Approved Approved Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA011391: AB_10603876, HPA076623: AB_2686809" "unprognostic (1.17e-1)" "prognostic favorable (6.33e-4)" "unprognostic (2.35e-2)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" "unprognostic (8.51e-2)" "unprognostic (2.33e-1)" "unprognostic (3.75e-2)" "unprognostic (3.61e-1)" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (3.20e-1)" "unprognostic (4.75e-3)" "unprognostic (1.06e-1)" "unprognostic (4.66e-2)" "unprognostic (3.94e-2)" "unprognostic (2.97e-2)" 72.6 42.3 10.7 57.5 10.9 33.5 40.0 10.8 22.5 28.1 14.7 41.0 27.8 14.3 9.6 25.7 16.8 61.4 22.8 10.0 11.8 11.5 108.6 56.4 109.1 15.8 13.7 12.3 7.8 8.7 9.8 65.2 14.8 12.4 54.9 1.4 16.0 18.3 5.3 7.3 45.1 52.6 12.4 121.5 24.5 7.8 13.6 32.2 10.0 17.7 47.6 59.9 8.6 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 4.1 0.0 5.7 0.0 0.0 0.0 0.0 4.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 47.9 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 4.1 0.0 406.4 1095.3 8.2 1.6 345.6 3.4 9.6 2.2 1.4 638.8 1.5 1.0 1.0 72.8 2.1 24.4 454.4 1.9 752.8 10.7 10.9 10.8 22.5 10.0 11.8 15.8 13.7 14.8 12.4 13.6 17.6 5.3 6.4 22.9 0.0 16.1 9.3 0.6 0.0 1.2 0.3 2.2 8.0 3.3 17.2 2.5 3.7 0.0 2.0 220.6 0.3 0.0 0.0 2.2 0.4 0.2 12.8 0.0 43.9 0.1 0.0 2.7 4.3 2.6 0.2 13.9 0.1 580.8 20.5 376.8 0.0 0.1 0.1 0.0 1649.6 470.0 5.1 1.5 675.9 14.2 40.3 429.2 0.0 11.3 0.5 0.1 0.0 1.2 0.0 2.0 0.2 0.0 0.5 1.5 0.6 46.0 3.0 4.4 0.5 1.1 2.4 8.0 2.1 10.4 0.1 0.2 0.3 MS4A7 "CD20L4, CFFM4, MS4A8" ENSG00000166927 "Membrane spanning 4-domains A7" Q9GZW8 11 60378485-60395951 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 196.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 311.4;Kupffer cells: 1060.3;Macrophages: 567.5;monocytes: 184.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "intermediate monocyte: 747.4;non-classical monocyte: 1486.0" "Lineage enriched" "Detected in many" 12 "monocytes: 1486.0" "Cell line enriched" "Detected in some" 25 "THP-1: 114.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA017418, CAB026387" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB026387: , HPA017418: AB_1854137" "unprognostic (1.43e-1)" "unprognostic (2.60e-3)" "unprognostic (3.24e-2)" "unprognostic (9.67e-2)" "unprognostic (2.04e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-1)" "unprognostic (9.51e-2)" "unprognostic (3.02e-2)" "unprognostic (4.85e-2)" "unprognostic (5.79e-2)" "unprognostic (1.90e-1)" "unprognostic (1.43e-2)" "unprognostic (4.59e-2)" "unprognostic (3.90e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" 46.9 37.6 6.3 50.9 5.0 10.7 30.7 4.5 13.7 18.2 13.9 21.4 17.6 7.6 4.1 12.7 6.6 46.8 9.9 4.2 8.7 8.0 66.5 75.7 23.2 12.8 10.4 6.0 6.0 9.0 4.7 43.9 11.4 4.9 23.3 1.2 6.7 9.0 1.9 2.3 25.1 15.9 7.4 196.6 14.8 4.7 17.1 18.2 7.3 4.1 18.6 41.2 3.9 18.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 2.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.5 0.1 0.0 0.1 1.1 0.1 0.1 0.0 2.8 0.0 0.1 0.1 0.8 0.5 0.0 0.0 114.2 0.0 0.1 0.1 0.1 0.1 0.2 0.2 3.0 0.0 3.1 0.0 8.3 188.0 2.5 0.8 747.4 1.1 22.3 0.6 0.5 120.9 19.7 0.8 0.4 9.3 0.8 1486.0 3.2 0.9 137.8 6.3 5.0 4.5 13.7 4.2 8.7 12.8 10.4 11.4 7.4 17.1 18.3 5.0 12.8 31.4 0.0 30.6 2.7 0.8 0.0 0.6 3.6 14.7 9.9 2.1 0.0 3.7 9.2 0.0 1.0 1.4 0.3 0.0 0.0 2.4 0.1 0.0 12.2 0.0 10.1 0.1 0.2 1.7 3.9 1.5 0.1 13.9 0.1 11.0 4.7 311.4 0.0 0.2 0.0 0.0 1060.3 93.4 1.2 1.2 567.5 1.8 59.0 184.8 0.4 4.1 0.0 0.3 0.1 1.1 0.0 1.8 1.1 0.0 0.7 7.3 0.5 19.7 2.2 1.2 0.0 0.4 0.9 1.8 1.9 5.3 0.3 0.1 1.0 MSR1 "CD204, SCARA1, SR-A, SR-AI, SR-AII, SR-AIII" ENSG00000038945 "Macrophage scavenger receptor 1" P21757 8 16107878-16567490 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lung: 120.1" "Group enriched" "Detected in many" 5 "Hofbauer cells: 137.3;Kupffer cells: 322.8;Langerhans cells: 86.0;Macrophages: 172.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 16.9" "Lineage enriched" "Detected in many" 5 "monocytes: 16.9" "Group enriched" "Detected in many" 7 "BJ hTERT+: 105.2;REH: 40.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000272, CAB032491" Enhanced NA NA 67000 "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032491: AB_672722, HPA000272: AB_1846269" "unprognostic (8.19e-3)" "unprognostic (4.87e-2)" "unprognostic (1.93e-2)" "unprognostic (2.10e-1)" "unprognostic (9.24e-2)" "unprognostic (1.32e-2)" "unprognostic (5.85e-3)" "unprognostic (2.89e-1)" "unprognostic (9.70e-2)" "unprognostic (1.62e-2)" "unprognostic (7.19e-2)" "unprognostic (8.82e-2)" "unprognostic (2.76e-2)" "unprognostic (9.16e-2)" "unprognostic (7.39e-2)" "unprognostic (6.85e-2)" "unprognostic (4.69e-2)" 25.9 18.4 4.2 17.5 5.4 13.0 9.7 5.5 10.6 11.6 13.6 8.5 6.6 8.0 6.3 6.2 5.6 29.8 8.7 3.8 6.5 6.7 24.9 120.1 7.0 15.0 7.5 6.1 11.4 6.3 2.6 27.4 10.8 3.6 10.6 5.9 6.3 6.4 2.3 3.5 9.4 17.9 6.9 16.0 6.2 6.2 16.9 4.4 5.2 1.4 2.9 17.4 1.9 22.9 1.5 2.1 3.0 1.5 1.4 1.3 1.4 0.7 105.2 0.3 0.6 3.7 0.4 3.4 5.1 1.0 0.7 0.7 0.7 1.0 2.0 0.4 4.3 4.6 5.1 4.2 0.9 2.4 2.5 0.7 0.8 0.8 1.5 1.8 0.2 1.9 1.7 2.9 1.9 4.3 1.4 1.4 0.5 1.6 1.3 40.7 2.3 1.0 2.0 5.8 2.8 1.2 1.0 2.8 0.2 5.0 0.4 1.2 2.4 2.8 0.9 10.8 2.8 9.5 8.6 7.4 1.1 1.5 2.2 1.7 3.3 0.6 1.0 16.9 0.4 1.1 0.7 0.7 1.1 1.5 1.3 0.9 3.2 0.4 8.8 0.5 0.7 0.8 4.2 5.4 5.5 10.6 3.8 6.5 15.0 7.5 10.8 6.9 16.9 22.9 2.0 22.4 35.9 0.0 2.7 2.7 0.0 0.0 0.0 1.6 0.5 1.4 2.0 2.8 8.1 3.7 25.0 0.5 0.1 0.0 1.9 0.0 2.9 0.0 0.0 6.3 0.0 2.7 0.3 0.0 1.0 2.1 0.0 0.0 17.7 0.1 4.6 1.7 137.3 0.0 3.0 0.1 0.0 322.8 86.0 3.6 1.8 172.5 0.0 28.1 3.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.4 6.6 0.7 19.7 1.0 0.7 4.2 1.3 0.1 2.0 0.8 2.6 0.2 0.0 0.3 NCKAP1L HEM1 ENSG00000123338 "NCK associated protein 1 like" P55160 12 54497752-54548243 "Plasma proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 44.9" "Cell type enhanced" "Detected in many" "B-cells: 66.2;dendritic cells: 92.3;Hofbauer cells: 115.5;Kupffer cells: 175.1;Macrophages: 108.1;monocytes: 153.2;NK-cells: 113.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HL-60: 112.4;HMC-1: 112.4;NB-4: 82.6;REH: 59.1;THP-1: 121.3;U-937: 70.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039490, HPA040772" Approved Uncertain "Plasma membrane,Cytosol" NA NA 33000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "Plasma membrane" "HPA039490: AB_2676540, HPA040772: AB_2677129" "unprognostic (4.54e-2)" "unprognostic (5.20e-3)" "unprognostic (1.61e-2)" "unprognostic (1.22e-3)" "unprognostic (9.29e-2)" "unprognostic (1.01e-2)" "unprognostic (3.69e-1)" "unprognostic (2.95e-2)" "unprognostic (6.53e-3)" "unprognostic (4.80e-1)" "unprognostic (1.76e-1)" "unprognostic (2.08e-1)" "unprognostic (1.54e-3)" "unprognostic (2.57e-1)" "unprognostic (2.76e-2)" "unprognostic (3.63e-2)" "unprognostic (4.74e-2)" 9.7 4.6 3.3 34.8 4.0 28.4 4.7 3.6 3.7 4.0 4.0 19.7 5.8 2.5 1.3 6.1 3.4 7.3 2.6 2.9 3.7 2.3 7.1 20.2 42.5 6.9 4.8 1.8 1.6 4.0 1.5 11.0 6.5 4.7 9.7 0.4 3.5 5.2 1.2 2.3 18.1 10.3 5.4 44.9 6.7 1.2 6.8 37.4 2.2 2.0 43.4 27.9 2.8 8.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 47.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 40.4 0.3 47.9 0.0 0.0 0.0 112.4 112.4 0.0 0.0 0.0 0.0 0.0 0.7 40.1 7.7 43.7 0.0 0.0 47.9 82.6 0.1 0.0 0.0 59.1 0.2 47.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 121.3 0.0 0.2 0.0 0.1 0.1 2.4 2.9 38.4 0.2 70.4 0.0 31.7 68.6 55.0 31.7 103.9 26.2 30.2 28.3 32.7 72.0 28.8 17.9 26.4 16.9 36.1 121.3 40.8 45.1 65.1 3.3 4.0 3.6 3.7 2.9 3.7 6.9 4.8 6.5 5.4 6.8 8.4 1.0 0.0 11.6 0.3 66.2 1.3 0.3 0.0 0.0 1.3 0.6 2.2 1.5 4.3 1.8 0.0 0.0 0.7 92.3 0.2 0.0 0.1 0.9 0.2 0.3 3.6 0.0 22.1 0.8 0.4 1.0 2.7 2.0 0.3 56.3 0.1 7.5 1.4 115.5 0.0 0.5 0.0 0.0 175.1 28.5 2.3 1.2 108.1 5.4 42.2 153.2 0.4 113.3 0.5 0.0 0.0 0.1 0.0 40.0 0.1 0.0 0.3 0.7 0.9 0.0 0.8 1.3 0.9 1.6 0.1 0.6 1.4 59.7 0.2 0.0 0.2 P2RY12 "HORK3, P2Y12, SP1999" ENSG00000169313 "Purinergic receptor P2Y12" Q9H244 3 151336843-151384753 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.8;lymphoid tissue: 9.8" "Cell type enriched" "Detected in some" 27 "Microglial cells: 421.6" "Cancer enriched" "Detected in many" 14 "glioma: 17.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 8.3" "Group enriched" "Detected in many" 11 "dendritic cells: 3.2;monocytes: 8.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013796, HPA014518" Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 68: Oligodendrocytes - Mixed function" "HPA013796: AB_1854884, HPA014518: AB_2669027" "unprognostic (2.39e-2)" "unprognostic (1.60e-3)" "unprognostic (5.93e-2)" "unprognostic (1.77e-1)" "unprognostic (2.41e-2)" "unprognostic (2.52e-2)" "unprognostic (8.09e-2)" "unprognostic (1.72e-3)" "unprognostic (6.46e-2)" "unprognostic (8.64e-4)" "unprognostic (4.84e-2)" "unprognostic (5.96e-2)" "unprognostic (2.03e-1)" "unprognostic (8.92e-2)" "unprognostic (1.65e-1)" "unprognostic (3.52e-2)" "unprognostic (4.04e-1)" 8.6 4.0 4.8 1.9 5.1 0.5 3.7 5.1 6.1 1.3 2.4 1.6 1.2 0.7 0.6 1.2 2.5 2.2 1.3 5.7 6.9 0.6 2.5 2.5 9.8 10.2 8.1 1.6 0.8 1.6 0.3 2.3 11.8 0.9 1.4 0.3 2.9 2.0 0.1 0.4 2.8 1.6 11.5 5.5 1.1 0.2 8.5 0.9 0.5 0.6 8.7 1.1 0.4 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 8.3 0.0 0.3 0.0 0.0 3.2 0.5 0.0 0.0 0.3 0.0 2.2 0.3 0.0 1.3 4.8 5.1 5.1 6.1 5.7 6.9 10.2 8.1 11.8 11.5 8.5 13.8 0.2 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.5 0.0 0.0 0.3 0.0 0.0 1.3 0.0 0.0 0.0 0.2 0.0 2.1 0.0 0.0 2.6 0.0 0.0 0.0 3.1 0.0 421.6 0.7 0.4 0.0 15.6 4.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 PEAK3 "C19orf35, FLJ45778" ENSG00000188305 "PEAK family member 3" Q6ZS72 19 2274631-2282175 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.3;lymphoid tissue: 4.1" "Cell type enhanced" "Detected in some" "dendritic cells: 1.5;Hofbauer cells: 1.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 41.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 41.0" "Cell line enriched" "Detected in some" 9 "HMC-1: 12.2" "Group enriched" "Detected in some" 5 "basal ganglia: 6.7;cerebellum: 3.1" HPA057806 Uncertain Uncertain Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "HPA057806: AB_2683534" "unprognostic (9.42e-2)" "unprognostic (3.26e-2)" "unprognostic (7.27e-2)" "unprognostic (6.23e-2)" "unprognostic (2.65e-2)" "unprognostic (8.40e-3)" "unprognostic (3.67e-1)" "unprognostic (3.08e-1)" "unprognostic (1.81e-1)" "unprognostic (2.08e-1)" "unprognostic (6.89e-2)" "unprognostic (1.43e-1)" "unprognostic (2.19e-2)" "unprognostic (2.01e-1)" "unprognostic (3.57e-2)" "unprognostic (3.20e-2)" "unprognostic (1.90e-1)" 0.5 0.4 0.5 1.3 0.9 2.3 0.3 0.5 1.6 0.2 0.1 0.4 0.2 0.2 0.0 0.2 0.5 0.2 0.7 0.4 0.5 0.3 0.2 1.1 0.4 1.4 1.0 0.1 0.2 0.0 0.2 0.1 1.0 0.3 0.2 0.0 0.2 0.0 0.3 0.3 0.8 0.1 0.9 4.1 0.3 0.1 0.8 0.1 0.2 0.0 0.3 0.3 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.4 0.0 12.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 10.5 4.4 11.7 1.6 5.7 0.2 0.2 0.1 0.2 1.8 0.4 0.1 0.3 41.0 4.5 1.9 0.2 0.0 1.1 0.5 0.9 0.5 1.6 0.4 0.5 1.4 1.0 1.0 0.9 0.8 0.6 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 PIK3R5 "p101, P101-PI3K" ENSG00000141506 "Phosphoinositide-3-kinase regulatory subunit 5" Q8WYR1 17 8878911-8965712 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 87.4" "Cell type enhanced" "Detected in some" "dendritic cells: 29.9;Kupffer cells: 35.7;Langerhans cells: 40.5;Macrophages: 36.8;Microglial cells: 79.6;NK-cells: 32.0;Plasma cells: 24.7;T-cells: 25.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 39.2;HMC-1: 5.7;JURKAT: 13.7;U-937: 11.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA044505, HPA052247, HPA052412" Uncertain Supported "Centriolar satellite,Cytosol" No NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Centriolar satellite" "HPA044505: AB_2678964, HPA052247: AB_2681772, HPA052412: AB_2681823" "unprognostic (2.81e-1)" "unprognostic (1.31e-2)" "unprognostic (3.10e-2)" "unprognostic (2.37e-2)" "unprognostic (3.44e-2)" "unprognostic (9.89e-3)" "unprognostic (1.42e-1)" "unprognostic (5.70e-2)" "unprognostic (1.38e-1)" "unprognostic (7.95e-2)" "unprognostic (1.33e-2)" "unprognostic (2.66e-1)" "unprognostic (7.59e-3)" "unprognostic (6.89e-2)" "unprognostic (1.09e-1)" "unprognostic (1.94e-1)" "unprognostic (1.24e-1)" 6.5 3.6 1.4 19.7 1.3 87.4 2.7 1.3 7.5 2.1 1.6 3.3 3.3 1.4 0.8 2.5 3.0 6.6 1.8 1.3 1.7 1.4 2.9 14.1 13.7 4.0 2.7 0.8 1.3 0.8 0.8 3.1 3.6 1.5 2.6 0.0 2.1 1.0 0.7 1.5 9.5 3.9 2.8 22.4 3.6 2.2 6.8 12.3 1.7 0.9 8.9 6.5 1.4 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.2 0.4 1.5 0.0 0.0 0.0 0.5 5.7 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 0.0 0.3 1.5 2.5 0.6 0.0 0.0 4.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 9.5 16.1 5.7 18.1 14.3 11.8 4.3 10.1 15.6 11.5 5.7 7.5 12.0 34.4 8.6 19.0 9.0 13.2 16.2 1.4 1.3 1.3 7.5 1.3 1.7 4.0 2.7 3.6 2.8 6.8 5.4 0.2 0.0 6.1 0.7 11.7 1.0 0.0 0.0 0.0 0.0 0.2 0.3 2.1 1.5 0.0 0.0 0.0 0.1 29.9 0.0 0.0 0.1 4.5 0.1 0.1 0.7 0.0 4.0 0.3 0.0 0.3 0.5 1.5 0.1 5.1 0.0 1.4 0.4 18.3 0.0 0.5 0.0 0.0 35.7 40.5 12.2 0.3 36.8 1.8 79.6 19.8 0.0 32.0 1.0 0.3 0.0 0.0 0.0 24.7 0.1 0.0 0.2 0.0 0.0 0.0 0.4 1.4 0.6 0.4 0.1 0.9 0.4 25.7 0.0 0.0 0.0 SCIMP "C17orf87, DTFT5783, FLJ32580, MGC163426, MGC163428, UNQ5783" ENSG00000161929 "SLP adaptor and CSK interacting membrane protein" Q6UWF3 17 5208920-5234860 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 49.2" "Cell type enhanced" "Detected in many" "B-cells: 66.4;Hofbauer cells: 26.2;Kupffer cells: 120.3;Macrophages: 66.3;monocytes: 60.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 2.7" "Group enriched" "Detected in many" 8 "classical monocyte: 110.6;intermediate monocyte: 239.0;memory B-cell: 145.8;myeloid DC: 84.2;naive B-cell: 124.5;non-classical monocyte: 265.5" "Group enriched" "Detected in all" 9 "B-cells: 145.8;dendritic cells: 84.2;monocytes: 265.5" "Cell line enhanced" "Detected in many" "HeLa: 6.8;U-698: 10.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006117 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA006117: AB_1858633" "unprognostic (2.53e-2)" "unprognostic (7.88e-3)" "unprognostic (1.26e-2)" "unprognostic (5.79e-3)" "unprognostic (1.10e-1)" "unprognostic (3.87e-2)" "unprognostic (7.96e-2)" "unprognostic (1.73e-2)" "unprognostic (4.93e-2)" "unprognostic (2.99e-1)" "unprognostic (1.35e-1)" "unprognostic (8.05e-2)" "unprognostic (3.33e-2)" "unprognostic (2.07e-1)" "unprognostic (4.42e-2)" "unprognostic (1.77e-1)" "unprognostic (9.95e-2)" 5.9 4.1 0.0 30.4 0.1 5.1 1.4 2.7 1.3 1.5 3.6 4.5 5.4 2.9 1.1 1.9 3.1 7.3 1.7 0.3 0.0 2.3 10.6 16.2 39.4 0.6 0.1 3.6 3.9 0.8 0.7 3.9 0.1 3.1 4.6 7.5 4.0 1.4 4.3 3.2 10.2 6.1 0.0 49.2 5.0 2.8 0.0 5.1 3.4 0.8 44.9 6.0 0.6 0.4 1.0 1.5 2.5 3.3 0.0 0.0 2.5 1.1 0.0 0.0 0.0 0.7 2.1 4.8 0.9 0.0 1.8 1.0 0.0 0.0 0.0 0.8 2.1 2.0 6.8 0.7 0.0 0.2 0.7 0.0 0.1 0.0 0.2 1.2 0.0 4.2 0.1 1.2 0.0 1.6 2.4 0.7 1.1 0.3 1.4 2.2 0.5 0.5 0.0 0.6 1.8 0.8 1.8 0.6 1.3 0.7 2.6 2.4 0.3 0.3 1.1 1.4 0.6 0.7 0.3 10.8 1.2 0.3 0.7 16.8 110.6 3.0 1.3 239.0 1.5 145.8 0.8 1.2 84.2 124.5 1.7 1.2 19.0 5.3 265.5 3.2 1.4 68.0 0.0 0.1 2.7 1.3 0.3 0.0 0.6 0.1 0.1 0.0 0.0 0.4 0.5 0.0 4.4 2.6 66.4 0.4 0.4 0.0 0.0 2.5 0.4 0.5 0.4 1.5 0.6 0.0 12.5 0.3 1.5 0.0 0.0 0.7 1.4 0.4 0.3 2.0 0.0 0.4 6.5 0.9 0.3 0.6 0.0 0.1 1.3 0.4 3.3 1.9 26.2 1.7 4.9 0.0 0.0 120.3 4.2 0.7 0.3 66.3 0.0 8.4 60.3 0.4 10.3 4.0 2.3 0.4 0.0 0.4 1.7 0.3 0.0 1.0 1.6 4.1 0.0 0.7 0.3 0.5 0.8 0.0 0.4 0.1 3.2 0.2 0.0 0.4 SELPLG "CD162, PSGL-1" ENSG00000110876 "Selectin P ligand" Q14242 12 108621895-108633894 "Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 86.6" "Cell type enhanced" "Detected in many" "dendritic cells: 159.7;Kupffer cells: 84.9;Macrophages: 64.8;monocytes: 123.8;NK-cells: 154.5;Plasma cells: 65.1;T-cells: 65.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 136.2;HMC-1: 130.0;JURKAT: 102.2;Karpas-707: 195.1;RPMI-8226: 286.7;U-266/70: 326.8;U-266/84: 214.5" "Low region specificity" "Detected in all" "CAB002431, HPA011256, HPA069062" Enhanced Approved Vesicles NA NA 2700000 "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "CAB002431: AB_563509, HPA011256: , HPA069062: " "unprognostic (2.32e-2)" "prognostic favorable (1.46e-4)" "unprognostic (3.64e-3)" "unprognostic (1.02e-2)" "unprognostic (6.32e-2)" "prognostic favorable (6.94e-4)" "unprognostic (2.52e-1)" "unprognostic (1.29e-1)" "prognostic favorable (2.92e-4)" "unprognostic (2.26e-1)" "unprognostic (2.12e-2)" "unprognostic (3.24e-1)" "prognostic unfavorable (5.86e-4)" "unprognostic (5.88e-2)" "unprognostic (2.37e-2)" "prognostic favorable (2.74e-4)" "unprognostic (5.44e-2)" 17.5 9.1 12.1 47.4 10.5 21.1 6.9 11.7 12.1 9.2 8.2 9.6 8.6 3.7 2.1 8.6 7.8 17.0 5.0 12.0 14.1 4.0 6.5 40.8 62.2 17.8 13.5 2.8 3.4 4.4 3.0 13.0 16.4 3.3 8.4 0.7 7.0 3.9 2.2 4.7 15.5 11.5 17.0 86.6 11.3 2.2 17.2 52.1 3.4 7.3 30.6 21.5 3.3 24.5 0.5 0.4 1.4 0.8 0.7 1.5 0.8 4.9 4.8 1.8 1.4 0.3 1.9 0.5 1.7 7.4 2.0 0.3 0.1 0.1 1.3 136.2 0.0 45.7 0.2 0.2 0.4 35.1 130.0 1.8 0.5 2.5 0.6 5.0 0.4 102.2 0.8 195.1 6.0 0.0 28.3 18.9 0.2 0.1 1.6 0.3 0.5 286.7 2.9 0.0 0.3 0.0 0.6 0.2 2.2 3.3 0.1 42.6 1.7 2.6 0.8 3.5 1.4 326.8 214.5 6.4 1.5 74.2 1.9 1543.6 297.6 940.2 419.2 509.2 344.3 22.0 396.6 362.9 299.9 22.3 300.3 323.7 1257.2 309.2 762.7 518.3 662.2 1035.5 12.1 10.5 11.7 12.1 12.0 14.1 17.8 13.5 16.4 17.0 17.2 24.5 1.2 3.2 12.4 0.0 11.6 3.4 0.1 0.2 0.0 0.2 0.6 1.4 2.2 4.3 2.7 0.0 0.0 0.5 159.7 0.2 0.0 0.3 8.2 1.8 0.6 2.6 0.0 10.9 0.2 0.2 2.3 2.4 2.6 0.9 29.7 0.4 3.6 2.2 40.1 0.0 0.3 0.0 0.0 84.9 49.6 12.2 0.3 64.8 7.2 15.9 123.8 0.0 154.5 0.0 0.1 0.5 0.0 0.0 65.1 0.1 0.0 0.5 6.4 0.2 0.0 1.2 0.9 0.8 0.5 0.5 1.8 1.0 65.9 0.1 0.0 0.0 SERPINA5 "PAI3, PCI, PLANH3, PROCI" ENSG00000188488 "Serpin family A member 5" P05154 14 94561442-94593118 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Fertilization, Lipid transport, Transport" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 484.5;liver: 785.6;testis: 432.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 400.4;Endometrial ciliated cells: 175.2;Glandular and luminal cells: 345.3;Hepatocytes: 198.2;Late spermatids: 277.8;Peritubular cells: 144.4" "Cancer enhanced" "Detected in many" "liver cancer: 121.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "Hep G2: 261.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA078846 Enhanced "Secreted to blood" NA NA 2100000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 44: Endometrium - Transcription" "HPA078846: " "unprognostic (5.94e-3)" "unprognostic (2.64e-4)" "unprognostic (1.13e-1)" "prognostic favorable (7.72e-4)" "unprognostic (3.34e-3)" "unprognostic (6.10e-3)" "unprognostic (3.94e-2)" "unprognostic (1.39e-3)" "unprognostic (5.36e-1)" "unprognostic (1.50e-1)" "unprognostic (6.16e-2)" "unprognostic (1.87e-2)" "unprognostic (8.39e-3)" "unprognostic (3.38e-3)" "unprognostic (9.92e-2)" "unprognostic (8.08e-2)" "unprognostic (3.23e-1)" 5.1 484.5 1.8 3.3 2.4 0.0 19.6 2.2 1.7 29.6 3.0 5.3 5.5 31.8 1.2 0.8 26.3 160.5 19.0 1.6 7.2 151.4 785.6 1.0 3.6 3.5 3.8 30.1 173.9 0.2 3.2 0.1 5.3 6.8 1.9 14.0 9.4 153.3 46.4 3.3 3.6 2.1 1.7 112.2 12.1 432.4 2.8 0.9 4.1 152.6 4.7 2.3 4.0 3.7 0.8 0.1 2.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 12.0 12.2 0.0 8.3 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 261.3 0.3 0.4 0.0 1.7 0.3 0.1 0.0 2.3 4.9 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.7 0.2 0.0 0.1 0.5 0.2 3.9 0.1 0.4 17.4 0.2 0.1 7.9 0.9 0.1 0.0 0.5 0.0 0.6 0.4 1.5 0.2 0.1 0.2 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.4 2.2 1.7 1.6 7.2 3.5 3.8 5.3 1.7 2.8 3.7 0.9 0.0 0.0 0.0 0.1 0.8 0.0 0.1 0.0 0.2 18.9 14.1 0.8 400.4 0.1 33.1 2.1 0.0 0.1 0.0 64.6 103.2 78.7 175.2 19.7 40.3 0.0 2.7 0.0 122.2 0.0 18.2 0.5 345.3 0.0 78.2 2.5 198.2 0.0 8.4 0.0 0.0 0.0 3.2 0.7 277.8 57.2 1.9 0.0 0.0 0.6 5.4 0.0 0.0 0.2 18.3 0.0 144.4 0.0 0.1 0.0 7.5 0.0 1.4 6.6 11.6 1.5 11.1 2.9 0.0 0.6 0.3 1.8 58.7 0.0 0.1 SIGLEC1 "CD169, dJ1009E24.1, FLJ00051, FLJ00055, FLJ00073, FLJ32150, sialoadhesin, SIGLEC-1, SN" ENSG00000088827 "Sialic acid binding Ig like lectin 1" Q9BZZ2 20 3686970-3712600 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Endocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 11 "Hofbauer cells: 78.6;Kupffer cells: 93.4;Macrophages: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.5" "Lineage enhanced" "Detected in single" "monocytes: 1.5" "Cell line enriched" "Detected in single" 19 "THP-1: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA053457 Supported "Intracellular and membrane" NA NA 260000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA053457: AB_2682158" "unprognostic (2.05e-1)" "unprognostic (9.27e-3)" "unprognostic (3.83e-4)" "unprognostic (4.87e-3)" "unprognostic (3.40e-2)" "unprognostic (1.06e-1)" "unprognostic (2.15e-1)" "unprognostic (6.98e-2)" "unprognostic (2.27e-2)" "unprognostic (1.68e-1)" "unprognostic (1.40e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (8.69e-5)" "unprognostic (8.71e-2)" "prognostic unfavorable (4.36e-4)" "unprognostic (1.11e-2)" "unprognostic (9.31e-2)" 23.0 13.7 2.0 7.7 2.9 12.3 8.6 1.9 6.5 1.8 7.5 10.2 5.1 2.0 1.8 2.2 7.0 8.5 6.4 1.8 2.2 3.9 8.4 16.7 12.7 10.2 3.3 2.7 1.6 0.5 2.3 18.8 10.9 1.9 6.6 0.3 5.4 1.2 3.7 3.0 11.2 7.7 5.0 18.9 5.1 2.5 10.9 3.6 3.7 2.6 1.9 7.6 3.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 2.0 2.9 1.9 6.5 1.8 2.2 10.2 3.3 10.9 5.0 10.9 3.9 0.5 3.2 4.4 0.0 0.1 0.4 0.0 0.0 0.0 0.4 0.0 0.3 2.4 0.0 0.6 0.0 2.1 0.9 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.2 0.2 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 78.6 0.0 0.3 0.0 0.0 93.4 6.3 0.1 0.0 42.6 0.0 3.7 2.1 0.2 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 1.4 1.0 0.0 0.1 0.6 0.6 1.9 0.4 0.0 0.0 0.0 SIGLEC14 ENSG00000254415 "Sialic acid binding Ig like lectin 14" Q08ET2 19 51642553-51646801 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 28.3;lymphoid tissue: 40.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 18.5;Kupffer cells: 41.5;Macrophages: 13.5;monocytes: 24.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 109.1;intermediate monocyte: 125.1;myeloid DC: 65.4;neutrophil: 200.1;non-classical monocyte: 93.3" "Group enriched" "Detected in many" 7 "dendritic cells: 65.4;granulocytes: 200.1;monocytes: 125.1" "Group enriched" "Detected in some" 11 "HMC-1: 98.7;U-937: 24.7" "HPA014377, HPA014428" Uncertain Uncertain "Vesicles,Plasma membrane" NA NA 24000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane" "HPA014377: AB_2189277, HPA014428: " "unprognostic (3.05e-1)" "unprognostic (1.75e-1)" "unprognostic (6.47e-3)" "unprognostic (1.60e-1)" "unprognostic (3.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (9.77e-3)" "unprognostic (9.28e-2)" "unprognostic (6.73e-2)" "unprognostic (1.02e-1)" "unprognostic (4.28e-3)" "unprognostic (8.38e-2)" "unprognostic (4.17e-2)" "unprognostic (1.34e-1)" "unprognostic (1.89e-1)" 3.4 2.4 1.4 25.2 1.5 28.3 1.0 1.6 3.2 1.8 1.3 1.8 0.7 0.9 0.3 1.1 2.3 2.6 1.3 1.4 2.4 0.7 3.5 7.3 13.3 4.7 3.0 0.4 1.1 0.4 0.5 2.5 3.9 0.9 1.6 0.1 1.1 0.9 0.4 0.3 6.1 2.5 2.7 40.3 1.6 2.4 3.9 1.9 0.6 0.0 14.2 4.1 0.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 1.6 98.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 24.7 0.0 16.6 109.1 1.8 0.3 125.1 0.1 19.3 0.2 0.3 65.4 18.2 0.1 0.1 200.1 0.7 93.3 12.0 0.2 40.3 1.4 1.5 1.6 3.2 1.4 2.4 4.7 3.0 3.9 2.7 3.9 4.1 0.0 0.0 1.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.4 18.5 0.0 0.0 0.0 0.0 41.5 6.0 0.8 0.3 13.5 0.0 1.0 24.1 0.0 2.1 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 SIGLEC7 "CD328, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2" ENSG00000168995 "Sialic acid binding Ig like lectin 7" Q9Y286 19 51142299-51153526 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 31.3;Kupffer cells: 57.4;Macrophages: 33.1;monocytes: 15.5;NK-cells: 69.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 242.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Karpas-707: 55.4;RPMI-8226: 33.7;U-937: 35.0" HPA075513 Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 2600000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" Vesicles "HPA075513: " "unprognostic (3.14e-1)" "unprognostic (5.87e-2)" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (3.90e-2)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (2.78e-1)" "unprognostic (1.69e-1)" "unprognostic (4.95e-2)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.27e-2)" "unprognostic (6.61e-2)" "unprognostic (1.14e-3)" "unprognostic (2.58e-1)" "unprognostic (2.26e-2)" 3.7 2.9 0.9 10.6 1.0 4.6 1.0 1.0 1.9 0.6 1.2 1.9 1.6 0.5 0.4 0.4 1.2 2.6 1.3 0.8 1.3 1.6 7.4 5.0 7.7 2.1 1.5 0.4 0.5 0.7 0.6 6.2 1.9 0.7 2.4 0.2 0.7 0.4 0.2 0.2 2.2 3.8 1.4 19.2 0.9 0.9 2.2 1.5 0.5 0.3 2.4 3.1 0.5 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.4 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.1 33.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.1 0.0 1.2 1.1 0.0 0.2 35.0 0.0 3.2 140.2 242.1 10.6 105.8 18.9 3.8 0.2 4.8 65.5 0.2 0.3 4.4 116.7 96.8 44.0 2.9 0.0 80.9 0.9 1.0 1.0 1.9 0.8 1.3 2.1 1.5 1.9 1.4 2.2 2.4 0.4 0.0 2.2 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 1.8 0.0 0.2 8.3 0.1 0.0 0.0 0.4 0.0 0.2 0.6 0.0 8.8 0.0 0.0 0.2 0.3 0.0 0.0 1.3 0.0 6.1 0.8 31.3 0.0 0.0 0.0 0.0 57.4 3.5 0.0 1.5 33.1 0.0 0.0 15.5 0.0 69.0 0.0 0.0 0.1 0.0 1.2 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 3.5 0.4 0.0 0.0 SIGLEC8 "MGC59785, SAF2, SIGLEC-8, SIGLEC8L" ENSG00000105366 "Sialic acid binding Ig like lectin 8" Q9NYZ4 19 51450847-51458456 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.9;lymphoid tissue: 6.8" "Cell type enhanced" "Detected in some" "granulocytes: 44.9;Kupffer cells: 17.7;Microglial cells: 11.2" "Group enriched" "Detected in many" 4 "glioma: 7.2;renal cancer: 2.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 38 "eosinophil: 290.2" "Lineage enriched" "Detected in single" 719 "granulocytes: 290.2" "Cell line enriched" "Detected in some" 44 "HMC-1: 147.5" HPA012556 Uncertain Uncertain Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" Cytosol "HPA012556: AB_1856869" "unprognostic (1.27e-1)" "unprognostic (1.88e-4)" "unprognostic (1.28e-1)" "unprognostic (6.70e-2)" "unprognostic (2.97e-1)" "unprognostic (1.30e-2)" "unprognostic (7.84e-2)" "unprognostic (2.51e-2)" "unprognostic (2.72e-2)" "unprognostic (2.17e-1)" "unprognostic (1.10e-1)" "unprognostic (4.19e-1)" "unprognostic (8.62e-3)" "unprognostic (7.18e-2)" "unprognostic (6.02e-2)" "unprognostic (4.28e-3)" "unprognostic (3.29e-1)" 0.3 4.0 4.9 1.6 5.2 0.5 1.4 5.3 6.1 0.9 1.7 1.8 1.8 0.6 0.7 0.7 0.7 1.4 0.2 4.5 6.2 0.1 0.8 2.5 6.8 13.3 6.6 0.2 0.5 1.0 0.4 0.1 10.1 0.6 1.6 0.7 0.6 0.5 0.1 0.5 2.8 0.9 7.3 6.3 1.4 0.3 11.6 2.1 0.4 0.2 2.5 1.0 0.3 14.9 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 2.3 0.1 0.1 0.0 0.0 147.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.3 0.0 0.0 0.2 3.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.2 1.1 0.1 7.6 0.4 290.2 0.2 0.3 0.1 0.2 0.2 0.1 0.1 0.3 0.1 0.2 2.5 0.3 0.4 0.2 0.1 0.2 4.9 5.2 5.3 6.1 4.5 6.2 13.3 6.6 10.1 7.3 11.6 14.9 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 44.9 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 17.7 0.0 0.0 0.0 2.5 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 SIRPB2 "dJ776F14.2, PTPN1L, PTPNS1L3" ENSG00000196209 "Signal regulatory protein beta 2" Q5JXA9 20 1470741-1491587 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 5.1;Kupffer cells: 20.0;Macrophages: 9.5;Microglial cells: 14.0;monocytes: 8.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "classical monocyte: 51.1;eosinophil: 31.7;intermediate monocyte: 30.4;myeloid DC: 21.1;neutrophil: 69.5;non-classical monocyte: 24.4" "Group enriched" "Detected in many" 329 "dendritic cells: 21.1;granulocytes: 69.5;monocytes: 51.1" "Cell line enhanced" "Detected in some" "A-431: 4.7;HBEC3-KT: 4.0;HMC-1: 7.8;hTCEpi: 8.5;HUVEC TERT2: 4.3;THP-1: 7.7;TIME: 3.7;U-937: 8.3" "Low region specificity" "Detected in all" "HPA011548, HPA048032" Uncertain Approved "Nuclear bodies" NA NA 250000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nuclear bodies" "HPA011548: AB_2668514, HPA048032: AB_2680236" "unprognostic (3.22e-2)" "unprognostic (5.57e-2)" "unprognostic (2.29e-2)" "unprognostic (2.04e-1)" "unprognostic (1.45e-1)" "unprognostic (2.21e-2)" "unprognostic (2.07e-2)" "unprognostic (3.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.75e-1)" "unprognostic (2.38e-1)" "unprognostic (2.43e-1)" "unprognostic (3.50e-5)" "unprognostic (3.59e-3)" "unprognostic (9.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.06e-1)" 5.6 2.4 1.1 12.0 1.2 6.5 1.6 1.3 1.6 1.8 1.8 1.5 0.9 0.9 0.1 1.8 1.6 3.7 1.4 1.1 1.5 1.1 1.8 7.2 7.0 2.7 2.1 0.5 0.7 0.6 0.6 7.5 2.4 0.9 1.7 0.2 1.3 0.6 0.5 0.9 2.0 4.1 1.6 13.1 1.2 0.5 2.7 1.4 0.7 1.8 3.2 3.9 0.9 2.6 4.7 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 1.1 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 7.8 0.0 8.5 0.0 0.2 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 7.7 3.7 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 8.3 0.0 3.0 51.1 31.7 0.1 30.4 0.0 0.0 0.0 0.0 21.1 0.1 0.0 0.0 69.5 0.0 24.4 0.6 0.0 18.9 1.1 1.2 1.3 1.6 1.1 1.5 2.7 2.1 2.4 1.6 2.7 2.6 0.0 0.0 1.1 0.0 0.5 0.3 0.9 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.4 0.0 0.0 0.6 0.6 0.0 0.1 1.3 0.0 1.4 0.2 5.1 0.0 0.1 0.0 0.0 20.0 3.3 0.0 0.0 9.5 0.0 14.0 8.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.3 0.1 0.7 0.3 0.1 0.0 0.6 SLA "hSLAP, SLA1, SLAP, SLAP-1" ENSG00000155926 "Src like adaptor" Q13239 8 133036728-133102912 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 97.4;lymphoid tissue: 156.6" "Cell type enhanced" "Detected in many" "dendritic cells: 224.2;Hofbauer cells: 67.4;Kupffer cells: 199.4;Macrophages: 154.2;NK-cells: 109.2;Plasma cells: 83.0;T-cells: 160.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HMC-1: 47.9;JURKAT: 201.5;Karpas-707: 129.2;MOLT-4: 35.8;U-266/84: 76.1;U-937: 55.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012296, HPA074192" Enhanced Approved "Nuclear membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear membrane, Cytosol" "HPA012296: AB_1856946, HPA074192: AB_2686673" "unprognostic (1.19e-2)" "unprognostic (6.29e-3)" "unprognostic (2.73e-3)" "unprognostic (6.07e-3)" "unprognostic (1.66e-2)" "unprognostic (1.10e-2)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.67e-1)" "unprognostic (9.25e-2)" "unprognostic (3.03e-2)" "unprognostic (2.73e-1)" "unprognostic (2.80e-3)" "unprognostic (2.66e-1)" "unprognostic (3.05e-2)" "unprognostic (8.60e-2)" "unprognostic (1.65e-1)" 25.2 13.1 9.5 82.9 6.4 97.4 9.5 6.1 11.5 11.1 8.2 10.8 7.9 5.2 2.9 9.4 7.0 20.9 5.2 8.2 9.1 6.4 16.9 25.9 78.6 12.0 8.4 3.0 5.8 3.1 3.1 15.2 10.3 5.2 8.4 1.3 4.6 3.6 1.5 4.0 20.7 12.5 9.7 70.3 12.5 1.4 16.9 156.6 27.6 4.4 71.0 22.0 4.2 14.6 0.3 0.0 0.0 0.0 0.0 0.1 0.6 0.0 1.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.9 0.1 2.3 0.0 0.0 0.0 6.3 47.9 0.8 0.0 0.6 0.0 0.2 0.0 201.5 0.1 129.2 0.0 0.0 35.8 9.3 0.0 0.0 0.0 0.2 0.3 7.8 0.0 0.0 0.0 1.0 0.0 0.1 0.1 3.1 0.0 15.3 0.0 0.1 0.3 0.2 0.1 6.9 76.1 0.0 0.6 55.6 0.0 0.7 110.2 203.6 87.6 123.1 110.1 41.0 79.7 88.2 79.8 48.3 75.3 77.4 262.3 132.6 148.4 6.3 124.4 158.9 9.5 6.4 6.1 11.5 8.2 9.1 12.0 8.4 10.3 9.7 16.9 14.6 2.4 9.6 19.1 0.7 36.6 2.2 0.3 0.0 0.0 9.7 0.9 1.3 3.3 1.5 10.5 0.0 0.0 0.4 224.2 0.2 0.0 0.2 0.2 0.7 0.7 5.9 0.0 13.2 1.0 0.0 1.2 4.5 3.6 0.5 37.2 1.7 8.9 2.9 67.4 0.0 1.3 0.5 0.0 199.4 15.0 1.0 0.3 154.2 5.4 14.0 36.7 0.1 109.2 0.0 0.1 0.0 0.0 0.0 83.0 0.1 0.0 0.3 5.1 0.3 6.6 1.4 1.9 0.0 0.1 0.3 2.7 0.1 160.0 0.1 0.1 0.2 SLC37A2 FLJ00171 ENSG00000134955 "Solute carrier family 37 member 2" Q8TED4 11 125063302-125090516 "Predicted membrane proteins, Transporters" "Antiport, Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 78.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 13.4;Hofbauer cells: 36.5;Kupffer cells: 22.0;Macrophages: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 12.3;intermediate monocyte: 14.1;myeloid DC: 5.5;non-classical monocyte: 19.2" "Group enriched" "Detected in many" 9 "dendritic cells: 5.5;monocytes: 19.2" "Cell line enhanced" "Detected in many" "A-431: 33.8;CAPAN-2: 70.3;hTCEpi: 34.9;hTERT-HME1: 64.8;U-138 MG: 47.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014948 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "HPA014948: AB_2190374" "unprognostic (8.47e-2)" "unprognostic (4.85e-1)" "unprognostic (9.64e-2)" "unprognostic (2.91e-2)" "unprognostic (7.88e-2)" "unprognostic (2.84e-1)" "unprognostic (5.47e-2)" "unprognostic (1.68e-1)" "unprognostic (2.06e-2)" "unprognostic (1.30e-1)" "unprognostic (2.15e-2)" "unprognostic (3.11e-1)" "unprognostic (6.61e-2)" "unprognostic (1.94e-3)" "unprognostic (1.66e-3)" "unprognostic (7.01e-2)" "unprognostic (3.24e-2)" 4.2 24.2 1.7 16.9 2.6 1.4 4.6 2.4 3.7 2.3 2.1 8.0 9.1 1.0 1.3 13.4 1.2 5.1 1.5 1.9 2.3 0.7 5.9 5.9 5.7 4.3 2.7 1.0 1.2 1.1 0.2 7.4 3.8 2.6 10.2 0.5 78.8 1.4 0.6 20.9 7.7 3.1 3.2 15.8 2.1 1.6 5.2 2.1 0.6 0.9 5.1 11.9 7.7 7.3 33.8 0.1 1.0 0.4 0.6 0.8 0.6 1.6 2.8 1.0 2.5 0.2 70.3 0.4 9.4 0.4 2.5 21.0 0.4 20.9 3.8 0.9 0.6 6.6 1.6 2.4 0.1 0.3 0.9 0.7 34.9 2.6 64.8 2.7 1.7 1.3 0.5 2.2 3.1 0.3 0.3 4.6 1.9 0.2 1.0 0.4 2.7 0.8 1.0 17.6 0.3 0.3 4.8 2.9 2.6 0.5 0.3 1.8 3.7 47.2 1.9 0.7 1.6 1.8 1.5 1.1 1.7 2.4 4.1 0.2 12.3 0.0 0.0 14.1 0.0 0.4 0.0 0.1 5.5 0.1 0.1 0.1 1.3 0.0 19.2 0.2 0.0 5.4 1.7 2.6 2.4 3.7 1.9 2.3 4.3 2.7 3.8 3.2 5.2 7.3 0.7 0.0 0.6 0.3 3.8 0.3 1.4 0.5 1.2 1.5 1.4 1.1 1.1 1.5 1.6 0.0 2.1 0.6 0.7 13.4 0.0 0.1 1.6 1.9 1.4 1.3 0.0 2.7 0.3 0.0 0.8 0.5 0.0 4.9 2.5 0.4 1.8 0.3 36.5 0.0 0.3 0.1 0.0 22.0 1.4 2.2 0.9 22.7 0.0 8.4 7.3 0.3 3.1 1.0 0.2 0.1 3.3 1.2 1.7 1.0 0.0 0.1 0.2 0.8 0.0 0.8 0.6 2.7 1.1 5.7 0.9 3.4 1.2 0.4 0.1 3.2 STAB1 "CLEVER-1, FEEL-1, FELE-1, FEX1, KIAA0246, SCARH2, STAB-1" ENSG00000010327 "Stabilin 1" Q9NY15 3 52495338-52524495 "Predicted membrane proteins, Transporters" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 439.5" "Cell type enriched" "Detected in many" 4 "Hepatic stellate cells: 745.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 59 "classical monocyte: 9.4;intermediate monocyte: 5.7;myeloid DC: 2.5" "Group enriched" "Detected in many" 60 "dendritic cells: 2.5;monocytes: 9.4" "Group enriched" "Detected in some" 46 "HUVEC TERT2: 103.1;NB-4: 146.9;TIME: 128.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005434 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 96000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Cytosol "Nucleoplasm, Plasma membrane" "HPA005434: AB_1080097" "unprognostic (1.18e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (7.59e-4)" "unprognostic (3.63e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-2)" "unprognostic (1.08e-2)" "unprognostic (2.23e-1)" "unprognostic (2.38e-1)" "unprognostic (4.00e-3)" "unprognostic (2.66e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (3.88e-7)" "unprognostic (3.16e-2)" "unprognostic (9.40e-2)" "unprognostic (4.70e-2)" "unprognostic (1.08e-1)" 194.2 160.4 41.0 50.4 42.9 13.8 84.5 41.4 58.3 54.4 62.8 87.7 29.6 45.3 8.5 29.2 79.3 25.8 74.6 41.9 44.4 85.6 102.1 104.7 12.9 50.0 48.4 32.2 32.2 5.0 52.0 55.4 53.7 57.6 31.0 0.6 45.7 16.0 25.9 24.0 95.1 33.8 43.0 439.5 53.2 21.0 65.3 6.8 55.1 4.6 8.2 105.7 48.6 47.8 0.1 0.0 0.1 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.7 0.2 0.2 0.6 0.0 0.0 1.8 0.1 0.0 0.1 0.0 103.1 0.1 0.3 0.1 0.0 0.0 0.0 146.9 0.0 0.2 0.2 0.1 0.1 0.3 0.0 0.0 0.4 0.4 0.0 0.3 0.0 0.1 0.0 0.0 128.8 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.0 9.4 0.0 0.0 5.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 41.0 42.9 41.4 58.3 41.9 44.4 50.0 48.4 53.7 43.0 65.3 47.8 31.3 0.0 3.8 0.0 5.5 6.0 0.6 0.0 1.8 1.0 1.5 2.7 2.4 11.5 0.0 3.7 0.0 1.7 1.9 0.0 0.0 0.0 0.5 0.4 0.5 43.0 1.2 21.5 0.3 0.0 2.0 3.3 0.5 0.3 18.3 0.0 745.0 19.7 130.7 0.0 0.3 0.0 0.0 185.4 30.3 2.9 4.4 147.0 12.4 30.0 21.9 0.5 2.1 0.5 0.1 0.0 0.0 20.3 2.0 0.2 0.0 0.8 0.0 0.1 19.7 2.0 1.4 0.9 2.2 1.5 4.8 2.2 2.3 0.5 0.0 0.2 TBXAS1 "CYP5, CYP5A1, THAS, TS, TXAS, TXS" ENSG00000059377 "Thromboxane A synthase 1" P24557 7 139777051-140020325 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 57.8" "Group enriched" "Detected in many" 4 "granulocytes: 71.0;Hofbauer cells: 88.8;Kupffer cells: 193.6;Macrophages: 132.9;Microglial cells: 191.1;monocytes: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 14 "basophil: 324.3;classical monocyte: 322.4;eosinophil: 333.6;intermediate monocyte: 466.0;myeloid DC: 129.0;neutrophil: 271.1;non-classical monocyte: 423.1" "Group enriched" "Detected in all" 22 "dendritic cells: 129.0;granulocytes: 333.6;monocytes: 466.0" "Cell line enhanced" "Detected in many" "NB-4: 76.7;PC-3: 23.7;RPTEC TERT1: 21.0;U-937: 60.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA031257, HPA031258, HPA031259" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 890000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 4: Macrophages - Innate immune response" "Endoplasmic reticulum, Cytosol" "HPA031257: AB_2673812, HPA031258: AB_2673813, HPA031259: AB_2673814" "unprognostic (4.46e-2)" "unprognostic (3.07e-1)" "unprognostic (8.80e-2)" "unprognostic (1.12e-1)" "unprognostic (2.72e-1)" "unprognostic (9.41e-2)" "unprognostic (5.10e-2)" "unprognostic (3.12e-1)" "unprognostic (2.38e-1)" "unprognostic (3.07e-2)" "unprognostic (1.11e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.52e-1)" "unprognostic (5.00e-3)" "unprognostic (8.53e-2)" "unprognostic (5.34e-2)" 13.2 10.8 5.3 28.1 5.1 24.8 8.2 5.4 5.9 5.4 5.8 10.1 10.3 3.2 2.0 5.4 4.9 21.2 3.3 4.5 6.8 5.8 12.8 23.9 12.4 10.0 6.6 2.9 3.6 2.9 2.3 14.2 8.8 6.4 13.0 1.6 9.0 4.0 1.0 1.3 11.9 12.6 8.9 57.8 11.2 1.4 9.7 15.1 1.8 3.3 8.3 13.9 2.1 14.7 0.2 5.4 0.3 0.1 1.2 3.9 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 12.1 0.0 0.3 0.0 0.0 0.0 0.0 9.4 0.7 17.8 0.0 0.0 1.6 6.2 15.3 2.1 0.0 0.0 0.9 1.1 2.3 0.1 0.6 2.2 0.6 0.2 2.4 76.7 0.2 18.0 23.7 2.6 0.0 1.2 21.0 0.0 0.2 1.1 0.2 0.0 0.8 0.0 0.0 14.4 2.0 0.6 0.2 1.4 1.0 4.6 0.9 0.3 0.4 60.8 1.7 324.3 322.4 333.6 7.3 466.0 11.9 8.3 13.5 3.7 129.0 4.5 2.3 1.3 271.1 11.9 423.1 22.6 13.9 216.7 5.3 5.1 5.4 5.9 4.5 6.8 10.0 6.6 8.8 8.9 9.7 14.7 3.9 3.2 10.8 8.1 9.9 0.4 1.2 0.5 2.8 1.0 3.0 3.0 1.1 5.7 1.7 1.8 6.2 0.6 16.4 0.8 9.8 5.2 0.4 1.0 0.6 5.0 1.8 12.8 1.2 9.5 0.5 2.9 7.1 3.8 71.0 0.5 16.8 8.6 88.8 3.3 1.8 1.9 12.2 193.6 19.5 0.7 0.3 132.9 3.6 191.1 63.7 4.9 26.8 3.0 5.9 4.4 7.9 0.0 16.4 5.8 0.2 6.3 1.0 4.1 19.7 1.3 1.7 0.5 0.7 26.2 0.6 0.5 13.4 0.3 2.7 1.2 TFEC "bHLHe34, TCFEC, TFECL" ENSG00000105967 "Transcription factor EC" O14948 7 115935148-116159896 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.2;kidney: 20.5;lymphoid tissue: 22.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 45.5;Kupffer cells: 56.3;Macrophages: 61.6;Microglial cells: 60.0;monocytes: 44.1;Proximal tubular cells: 77.8" "Cancer enhanced" "Detected in many" "renal cancer: 5.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "classical monocyte: 7.1;intermediate monocyte: 2.8;memory B-cell: 3.8;myeloid DC: 6.3;naive B-cell: 2.5;plasmacytoid DC: 3.3" "Group enriched" "Detected in many" 29 "B-cells: 3.8;dendritic cells: 6.3;monocytes: 7.1" "Cell line enhanced" "Detected in some" "HEL: 15.9;HUVEC TERT2: 11.0;THP-1: 21.5;TIME: 12.5;U-937: 24.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB032260, HPA063577" Approved Supported Nucleoplasm NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "CAB032260: AB_2202845, HPA063577: AB_2685047" "unprognostic (1.36e-1)" "unprognostic (1.08e-2)" "unprognostic (8.70e-2)" "unprognostic (1.91e-2)" "unprognostic (1.44e-1)" "unprognostic (2.79e-2)" "unprognostic (1.13e-1)" "unprognostic (8.26e-2)" "unprognostic (2.15e-1)" "unprognostic (6.54e-2)" "unprognostic (2.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.05e-3)" "unprognostic (2.92e-1)" "unprognostic (4.14e-2)" "unprognostic (1.51e-1)" "unprognostic (3.60e-2)" 3.5 2.4 1.3 19.2 1.2 17.2 2.6 1.5 1.6 1.9 2.1 2.7 4.2 1.4 0.6 1.0 1.0 4.9 1.0 0.8 1.7 20.5 3.1 9.9 22.1 3.3 1.9 1.3 1.0 0.4 0.6 4.7 2.7 1.0 4.2 0.1 1.3 0.9 0.3 0.4 9.7 3.1 2.7 14.6 3.0 1.6 3.7 2.8 0.9 0.4 12.6 4.0 0.6 4.8 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 3.7 0.0 1.7 0.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 11.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 21.5 12.5 2.1 0.2 1.3 0.0 5.5 0.0 0.0 0.1 24.4 1.1 0.0 7.1 0.0 0.0 2.8 0.0 3.8 0.0 0.0 6.3 2.5 0.0 0.0 0.1 0.0 0.4 3.3 0.0 1.5 1.3 1.2 1.5 1.6 0.8 1.7 3.3 1.9 2.7 2.7 3.7 4.8 0.5 0.0 2.2 0.3 18.1 0.5 0.0 0.0 0.0 0.0 0.3 0.8 0.8 1.5 0.0 3.7 0.0 0.2 8.3 0.0 0.0 0.0 2.4 0.0 0.0 1.7 0.0 7.2 0.6 0.0 0.3 0.4 0.0 0.0 2.5 0.0 0.0 0.0 45.5 0.0 0.5 0.4 0.0 56.3 17.8 3.8 0.0 61.6 0.0 60.0 44.1 0.0 1.0 1.0 0.1 0.1 0.0 0.0 1.3 0.1 15.6 77.8 0.0 0.0 0.0 0.3 0.1 0.3 2.5 0.1 0.4 0.8 0.8 0.1 0.7 0.1 TLR8 CD288 ENSG00000101916 "Toll like receptor 8" Q9NR97 X 12906620-12923169 "CD markers, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 10.7;lymphoid tissue: 16.8" "Group enriched" "Detected in some" 6 "Kupffer cells: 49.8;Macrophages: 21.1;monocytes: 39.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 74 "classical monocyte: 16.7;intermediate monocyte: 14.9;myeloid DC: 8.4;neutrophil: 27.6;non-classical monocyte: 15.6" "Group enriched" "Detected in many" 78 "dendritic cells: 8.4;granulocytes: 27.6;monocytes: 16.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA001608 Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA001608: AB_1080295" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (3.96e-3)" "unprognostic (4.43e-2)" "unprognostic (9.63e-2)" "unprognostic (2.48e-2)" "unprognostic (2.59e-1)" "unprognostic (6.61e-2)" "unprognostic (1.93e-1)" "unprognostic (2.23e-1)" "unprognostic (3.72e-2)" "unprognostic (2.73e-1)" "unprognostic (1.74e-2)" "unprognostic (1.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.52e-1)" "unprognostic (5.66e-2)" 3.6 0.5 0.2 16.8 0.2 5.7 0.9 0.2 0.3 0.7 0.5 1.7 0.8 0.4 0.1 0.9 0.6 2.5 0.8 0.1 0.3 0.5 2.2 10.7 6.1 1.1 0.7 0.4 0.6 0.3 0.1 4.3 0.8 0.3 1.8 0.0 0.3 0.2 0.2 0.2 1.5 3.8 0.5 13.3 0.8 0.4 0.4 1.7 0.4 1.3 1.9 3.7 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.0 14.9 0.0 0.2 0.0 0.0 8.4 0.0 0.0 0.0 27.6 0.0 15.6 0.0 0.0 3.8 0.2 0.2 0.2 0.3 0.1 0.3 1.1 0.7 0.8 0.5 0.4 0.9 0.0 0.0 3.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 2.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.7 5.3 0.0 0.0 0.0 0.0 49.8 5.1 0.0 0.0 21.1 0.0 0.0 39.7 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 TM6SF1 ENSG00000136404 "Transmembrane 6 superfamily member 1" Q9BZW5 15 83107572-83144854 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 47.3" "Cell type enhanced" "Detected in many" "Adipocytes: 30.5;granulocytes: 44.4;Hofbauer cells: 50.9;Kupffer cells: 37.8;Langerhans cells: 46.4;Macrophages: 45.9;Microglial cells: 46.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 76.6;eosinophil: 195.8;neutrophil: 118.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 195.8" "Cell line enhanced" "Detected in some" "HEL: 23.2;HHSteC: 49.6;HUVEC TERT2: 27.7;JURKAT: 36.4;TIME: 68.3;U-698: 17.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016051, HPA056857" Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "HPA016051: AB_2203924, HPA056857: AB_2683259" "unprognostic (8.09e-2)" "unprognostic (1.31e-1)" "unprognostic (2.87e-2)" "unprognostic (4.67e-1)" "unprognostic (1.96e-1)" "unprognostic (1.43e-1)" "unprognostic (6.46e-2)" "unprognostic (3.52e-3)" "unprognostic (1.73e-1)" "unprognostic (1.70e-2)" "unprognostic (2.80e-1)" "unprognostic (2.55e-1)" "prognostic favorable (6.79e-4)" "unprognostic (1.15e-2)" "unprognostic (4.65e-3)" "unprognostic (2.60e-2)" "unprognostic (1.70e-1)" 6.5 3.9 5.4 5.2 6.0 5.3 4.6 7.7 8.8 3.3 6.3 2.6 2.0 2.8 2.1 3.1 2.8 3.7 9.6 5.2 5.6 1.9 2.3 10.7 5.7 6.8 6.0 1.7 1.2 1.8 0.9 7.8 6.6 2.1 2.6 2.8 2.9 1.3 47.3 1.8 2.6 3.9 6.9 6.2 2.1 3.6 5.4 2.2 10.4 21.8 3.0 3.8 1.5 7.6 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.3 5.6 0.0 0.2 0.0 0.3 0.1 1.0 0.0 0.3 0.0 3.7 0.0 0.0 0.0 0.3 23.2 0.0 0.0 49.6 1.6 0.1 0.2 0.0 0.0 0.1 0.3 27.7 36.4 0.9 0.0 0.4 0.0 0.0 3.0 0.6 0.0 0.0 0.0 4.2 0.0 0.1 0.4 1.2 0.3 0.2 0.0 1.9 0.5 0.0 14.9 68.3 0.6 0.9 0.1 0.3 2.1 0.0 17.0 0.1 3.4 0.1 76.6 31.7 195.8 5.0 13.4 0.0 0.3 0.5 0.8 18.9 0.9 0.1 0.8 118.1 5.0 6.4 2.6 0.0 11.8 5.4 6.0 7.7 8.8 5.2 5.6 6.8 6.0 6.6 6.9 5.4 7.6 30.5 0.0 6.0 2.9 0.9 2.4 0.1 0.4 0.6 1.6 0.5 1.8 1.2 1.5 0.8 0.0 0.0 0.3 7.5 0.0 0.0 0.2 13.1 0.6 0.2 16.7 0.0 4.4 18.7 2.0 0.4 1.5 0.0 0.3 44.4 0.0 7.9 0.1 50.9 0.0 22.4 0.0 0.0 37.8 46.4 7.4 0.9 45.9 3.6 46.9 19.4 0.5 16.5 2.0 1.9 0.4 0.0 0.0 0.7 0.1 0.0 0.0 1.4 1.3 0.0 1.4 0.6 13.1 7.5 0.1 1.7 0.3 4.2 0.1 0.0 0.1 TMEM86A FLJ90119 ENSG00000151117 "Transmembrane protein 86A" Q8N2M4 11 18693122-18704785 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 17.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 40.6;Theca cells: 17.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057119 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA057119: AB_2683342" "unprognostic (1.25e-1)" "unprognostic (1.09e-3)" "unprognostic (8.08e-3)" "unprognostic (1.89e-1)" "unprognostic (2.53e-1)" "unprognostic (1.10e-1)" "unprognostic (4.05e-2)" "unprognostic (2.94e-1)" "unprognostic (3.73e-1)" "unprognostic (1.74e-1)" "unprognostic (8.14e-2)" "unprognostic (2.67e-1)" "unprognostic (2.36e-1)" "unprognostic (1.50e-2)" "unprognostic (7.92e-2)" "unprognostic (4.20e-1)" "unprognostic (3.24e-1)" 2.8 2.7 2.6 2.2 2.2 0.3 3.2 2.1 2.8 2.3 3.8 1.5 1.4 2.2 1.0 2.3 2.6 4.0 2.9 2.1 2.6 9.5 2.6 3.5 4.7 3.1 2.7 7.1 3.4 5.4 2.2 4.3 2.5 1.6 1.8 5.7 2.7 1.4 2.9 17.6 2.0 1.9 2.7 4.9 2.1 2.3 4.0 1.6 2.1 2.5 2.5 2.3 3.6 4.5 0.0 0.2 0.6 3.1 2.7 0.0 0.1 0.6 0.5 0.5 0.5 0.0 0.4 0.0 1.2 0.6 3.0 0.3 0.2 0.1 0.3 0.2 1.9 0.2 0.1 0.0 2.1 0.0 2.8 3.8 1.2 0.1 0.2 0.7 1.7 1.8 0.6 0.0 1.3 1.7 0.0 0.0 0.2 0.5 1.6 0.0 5.1 0.0 17.5 3.8 1.0 1.3 1.0 3.2 1.4 1.1 3.9 0.4 1.9 0.5 0.2 0.1 0.1 3.2 2.7 0.0 1.1 0.0 1.1 0.0 1.9 0.1 0.2 1.4 0.5 0.0 0.2 0.4 3.4 0.1 0.4 0.8 0.0 0.1 0.5 2.0 0.5 0.8 2.6 2.2 2.1 2.8 2.1 2.6 3.1 2.7 2.5 2.7 4.0 4.5 1.9 0.0 0.0 0.3 0.0 0.1 0.8 0.4 0.0 5.2 3.5 1.8 2.2 0.0 0.7 11.0 8.4 0.5 1.4 0.6 7.9 7.8 12.2 1.1 1.9 2.1 3.5 0.0 0.5 8.0 0.3 1.7 1.1 1.0 0.0 3.0 3.9 1.6 40.6 0.0 0.8 0.8 0.0 12.7 0.8 12.1 2.1 8.3 0.0 3.7 2.3 2.6 0.0 2.0 0.1 7.4 0.1 1.9 0.4 0.6 0.0 8.3 0.4 4.8 6.6 0.4 1.2 7.8 2.6 0.2 0.3 2.3 0.7 17.4 0.2 0.4 TNFAIP8L2 FLJ23467 ENSG00000163154 "TNF alpha induced protein 8 like 2" Q6P589 1 151156649-151159749 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 70.4;Kupffer cells: 65.4;Macrophages: 35.8;monocytes: 34.7;NK-cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 29.8;HL-60: 17.6;HMC-1: 44.1;NB-4: 25.2;THP-1: 95.2;U-937: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062742 Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA062742: " "unprognostic (3.19e-3)" "unprognostic (1.02e-2)" "unprognostic (6.63e-3)" "unprognostic (2.27e-2)" "unprognostic (1.29e-1)" "unprognostic (6.49e-3)" "unprognostic (1.05e-1)" "unprognostic (9.15e-3)" "prognostic favorable (3.64e-4)" "unprognostic (9.54e-2)" "unprognostic (3.32e-2)" "unprognostic (9.03e-2)" "prognostic unfavorable (3.53e-7)" "unprognostic (1.78e-1)" "unprognostic (3.91e-2)" "unprognostic (4.87e-2)" "unprognostic (2.23e-1)" 4.7 4.3 4.9 19.6 5.4 6.1 3.4 5.1 7.5 2.3 5.7 4.5 5.3 1.5 1.4 2.5 2.2 5.5 2.3 4.7 5.2 2.0 5.6 10.8 32.0 6.5 5.7 1.0 1.4 1.2 1.2 6.9 7.0 2.1 6.1 0.9 2.6 1.8 0.8 3.8 7.6 5.4 6.4 39.2 3.4 0.8 6.3 19.2 1.3 2.2 17.7 7.8 1.4 8.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 29.8 0.4 0.0 0.0 17.6 44.1 0.0 0.0 0.0 0.0 0.0 0.4 2.5 0.1 0.1 0.0 0.1 0.4 25.2 0.0 0.0 0.1 5.3 0.1 4.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 95.2 2.5 0.2 0.1 0.1 0.2 0.3 0.0 1.9 0.1 37.8 0.1 317.0 238.8 246.7 103.2 220.2 101.9 78.3 125.7 105.2 265.4 83.2 189.5 137.3 292.3 232.9 210.6 63.0 155.7 249.5 4.9 5.4 5.1 7.5 4.7 5.2 6.5 5.7 7.0 6.4 6.3 8.1 0.3 0.0 1.7 0.0 6.9 0.3 0.0 0.0 0.0 0.8 0.8 0.3 0.1 2.8 1.3 0.0 0.0 0.3 11.1 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 8.8 0.0 0.0 0.5 0.2 0.0 0.0 5.1 0.0 0.7 0.3 70.4 0.0 0.0 0.0 0.0 65.4 12.8 0.4 0.3 35.8 0.0 0.0 34.7 0.0 48.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 1.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.4 10.6 0.0 0.0 0.0 TREM2 "TREM-2, Trem2a, Trem2b, Trem2c" ENSG00000095970 "Triggering receptor expressed on myeloid cells 2" Q9NZC2 6 41158506-41163186 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.8;lung: 30.1" "Cell type enriched" "Detected in many" 8 "Hofbauer cells: 1014.1" "Cancer enhanced" "Detected in all" "glioma: 93.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.0" "Lineage enhanced" "Detected in single" "dendritic cells: 2.0" "Group enriched" "Detected in some" 4 "hTCEpi: 74.6;THP-1: 42.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010917, HPA012571" Approved "Secreted in brain" NA NA 50000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "HPA010917: AB_1080365, HPA012571: AB_1858260" "unprognostic (3.89e-1)" "unprognostic (4.44e-3)" "unprognostic (2.77e-2)" "unprognostic (1.80e-2)" "unprognostic (1.29e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (4.83e-2)" "unprognostic (1.07e-1)" "unprognostic (8.57e-3)" "unprognostic (1.33e-1)" "unprognostic (2.09e-1)" "unprognostic (3.58e-3)" "unprognostic (8.04e-2)" "unprognostic (1.04e-2)" "unprognostic (3.16e-3)" "unprognostic (1.85e-2)" 10.7 13.2 28.1 3.5 31.1 0.2 9.8 33.7 61.5 6.5 29.1 3.5 0.9 1.6 2.3 0.6 7.4 9.7 2.1 27.5 32.3 1.3 2.3 30.1 2.6 44.5 34.4 2.4 3.9 7.4 3.9 10.7 42.7 2.0 4.3 1.9 6.0 3.1 0.4 0.5 1.4 4.5 46.7 0.5 2.5 0.7 43.5 1.8 1.7 0.0 0.4 4.5 0.6 69.8 0.0 0.3 0.0 0.0 0.1 0.3 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 1.2 74.6 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 42.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 28.1 31.1 33.7 61.5 27.5 32.3 44.5 34.4 42.7 46.7 43.5 69.8 1.8 6.4 7.5 0.0 0.7 0.8 0.2 79.8 0.0 0.3 1.8 58.8 0.1 1.5 9.6 0.0 0.0 5.0 0.4 0.0 0.0 0.0 0.6 0.0 0.1 10.4 0.0 0.0 0.0 0.0 4.9 1.2 0.0 0.0 2.5 0.0 2.2 0.2 1014.1 0.0 0.0 0.0 2.0 34.7 5.2 1.0 0.6 120.5 0.0 12.2 8.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 3.3 1.0 6.6 0.1 1.0 0.0 0.0 0.0 0.1 7.3 0.8 0.0 0.0 0.1 TYROBP "DAP12, KARAP, PLO-SL, PLOSL" ENSG00000011600 "Transmembrane immune signaling adaptor TYROBP" O43914 19 35904401-35908295 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 596.8;lymphoid tissue: 423.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3777.1;Kupffer cells: 3698.1;Langerhans cells: 1990.8;Macrophages: 2837.1;monocytes: 3371.2;NK-cells: 1772.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 6415.4" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "HMC-1: 678.1;THP-1: 390.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009493, HPA041899" Enhanced Supported "Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB009493: AB_638987, HPA041899: AB_10795266" "unprognostic (7.09e-2)" "unprognostic (8.38e-3)" "unprognostic (7.87e-2)" "unprognostic (4.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.39e-1)" "unprognostic (5.27e-2)" "unprognostic (8.04e-2)" "unprognostic (2.07e-2)" "unprognostic (2.47e-1)" "unprognostic (2.91e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.47e-2)" "unprognostic (1.72e-2)" "unprognostic (4.27e-2)" "unprognostic (4.39e-2)" 126.3 76.1 55.8 234.3 54.3 596.8 59.1 58.6 116.8 44.3 61.4 62.0 70.6 25.9 15.0 28.1 43.7 105.0 39.7 53.0 66.4 34.4 85.5 261.5 161.0 81.7 64.0 18.3 24.7 22.0 27.0 124.7 74.8 31.7 49.8 3.9 38.3 26.7 10.6 21.5 78.8 68.0 74.1 423.3 43.1 15.0 74.0 52.5 21.9 31.6 36.6 131.7 21.5 114.4 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 56.7 0.0 0.0 0.5 33.2 678.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 49.1 0.3 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.3 0.5 0.0 0.0 0.2 0.9 0.0 390.6 0.0 0.0 0.3 0.8 0.1 0.4 0.1 1.0 0.1 10.8 0.1 974.2 4983.5 2573.9 468.0 3367.8 246.5 22.4 9.5 64.2 1912.0 8.4 11.7 51.2 6415.4 1664.1 3413.8 1653.1 9.5 5260.2 55.8 54.3 58.6 116.8 53.0 66.4 81.7 64.0 74.8 74.1 74.0 114.4 24.5 57.7 168.4 0.0 50.9 55.2 2.0 0.0 1.2 0.1 11.5 43.3 6.8 34.3 43.4 20.2 0.0 19.8 987.6 1.7 1.9 2.1 3.9 1.3 1.4 47.1 0.0 87.8 0.1 5.8 28.0 24.9 5.6 1.5 753.7 0.3 73.2 25.0 3777.1 0.0 0.1 0.2 0.0 3698.1 1990.8 11.6 9.3 2837.1 56.9 18.7 3371.2 0.6 1772.4 0.0 0.1 1.3 2.3 1.2 19.4 1.5 0.5 8.9 20.5 1.8 78.9 5.3 10.0 0.9 3.0 4.9 44.6 38.9 236.5 0.1 0.5 1.8 VENTX "HPX42B, VENTX2" ENSG00000151650 "VENT homeobox" O95231 10 133237855-133241928 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Kupffer cells: 6.2;Langerhans cells: 7.9;Macrophages: 7.8;monocytes: 5.0" "Cancer enriched" "Detected in some" 15 "testis cancer: 30.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 7 "dendritic cells: 1.8;granulocytes: 1.9;monocytes: 3.2" "Group enriched" "Detected in some" 10 "NB-4: 18.2;NTERA-2: 10.9" HPA050955 Uncertain Uncertain "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 41: Macrophages - Immune response" "Nucleoli fibrillar center" Cytosol "HPA050955: AB_2681288" "unprognostic (9.41e-2)" "unprognostic (8.89e-2)" "unprognostic (2.34e-1)" "unprognostic (4.26e-1)" "unprognostic (3.22e-2)" "unprognostic (2.01e-1)" "unprognostic (2.54e-1)" "unprognostic (9.62e-3)" "unprognostic (2.22e-1)" "unprognostic (3.00e-3)" "unprognostic (3.70e-4)" "unprognostic (4.22e-1)" "unprognostic (2.51e-3)" "unprognostic (3.43e-2)" "unprognostic (3.48e-1)" "unprognostic (7.54e-2)" "unprognostic (3.14e-1)" 4.8 2.3 1.6 3.6 1.1 2.8 1.9 1.6 1.5 1.5 1.9 1.9 0.4 1.6 0.5 0.5 1.8 1.5 1.5 1.5 1.5 1.7 0.5 3.8 0.5 1.9 1.7 1.5 1.2 0.5 1.4 0.5 1.5 1.3 0.4 0.2 1.3 0.8 0.9 1.2 1.0 1.2 0.9 5.7 0.9 1.0 2.5 0.2 0.8 0.1 0.4 1.4 1.0 1.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 18.2 10.9 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 1.9 2.6 0.3 0.1 3.2 0.0 0.3 0.1 0.0 1.8 0.2 0.1 0.1 0.9 0.3 2.4 0.1 0.0 0.7 1.6 1.1 1.6 1.5 1.5 1.5 1.9 1.7 1.5 0.9 2.5 1.8 0.0 0.0 1.1 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 6.2 7.9 0.2 0.0 7.8 0.0 0.0 5.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0